BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1247 (napA-3) DE:Na+/H+ antiporter (napA-3)
         (380 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||C75016 na+/h+ antiporter (napa-3) PAB1247 - Pyrococcus abys...   717  0.0
pir||H71455 probable Na+/H+-exchanging protein - Pyrococcus hori...   631  e-180
pir||F71234 probable Na+/H+-exchanging protein - Pyrococcus hori...   318  7e-86
pir||C75201 na+/h+ antiporter (napa-1) PAB0084 - Pyrococcus abys...   312  6e-84
gb|AAB40041.1| (U17283) putative spore germination apparatus pro...   277  2e-73
gb|AAF91326.1|AF246294_2 (AF246294) GerN [Bacillus cereus]            269  3e-71
sp|P26235|NAPA_ENTHR NA(+)/H(+) ANTIPORTER >gi|282287|pir||A4211...   236  3e-61
emb|CAA51756.1| (X73329) Na/H antiporter homolog [Lactococcus la...   234  1e-60
pir||B71038 probable Na+/H+-exchanging protein - Pyrococcus hori...   234  2e-60
pir||C75176 na+/h+ antiporter (napa-2) PAB0390 - Pyrococcus abys...   230  2e-59
pir||S74414 Na+/H+-exchanging protein sll0689 - Synechocystis sp...   218  8e-56
pir||E70380 Na+/H+-exchanging protein - Aquifex aeolicus >gi|298...   213  3e-54
pir||C75103 na+/h+ antiporter (napa-4) PAB0809 - Pyrococcus abys...   172  5e-42
pir||H71083 probable Na+/H+-exchanging protein - Pyrococcus hori...   172  7e-42
pir||F70155 Na+/H+ antiporter (napA) homolog - Lyme disease spir...   170  2e-41
pir||B64459 Na+/H+-exchanging protein - Methanococcus jannaschii...   169  6e-41
pir||C82955 probable sodium/proton antiporter PA5529 [imported] ...   166  3e-40
dbj|BAB11467.1| (AB005233) Na+/H+ antiporter-like protein [Arabi...   145  6e-34
emb|CAB45049.1| (AL078635) putative integral membrane ion antipo...   142  6e-33
gb|AAK41390.1| Na(+)/H(+) antiporter [Sulfolobus solfataricus]        141  1e-32
pir||T05602 hypothetical protein F9D16.170 - Arabidopsis thalian...   141  1e-32
dbj|BAB02053.1| (AB022219) Na+/H+ exchangeing protein-like [Arab...   140  2e-32
gb|AAF26906.1|AF210843_3 (AF210843) unknown [Sorangium cellulosum]    134  2e-30
pir||S74951 Na+/H+-exchanging protein slr1595 - Synechocystis sp...   134  2e-30
pir||T45912 hypothetical protein F5K20.20 - Arabidopsis thaliana...   132  5e-30
gi|6322367 Yjl094cp [Saccharomyces cerevisiae] >gi|731972|sp|P40...   131  1e-29
gb|AAF24561.1|AC007764_3 (AC007764) F22C12.7 [Arabidopsis thaliana]   131  2e-29
pir||S76532 hypothetical protein - Synechocystis sp. (strain PCC...   127  3e-28
gb|AAD22684.1|AC007063_10 (AC007063) putative Na+/H+ antiporter ...   125  6e-28
dbj|BAB06563.1| (AP001516) Na+/H+ antiporter [Bacillus halodurans]    125  8e-28
pir||T50062 Probable K+/H+-antiporter [imported] - fission yeast...   121  1e-26
gi|11497833 Na+/H+ antiporter (napA-1) [Archaeoglobus fulgidus] ...   120  2e-26
gb|AAF69026.1| (AF182516) unknown [Pseudomonas putida]                114  2e-24
pir||C83496 glutathione-regulated potassium-efflux system protei...   112  6e-24
pir||A69845 Na+/H+ antiporter homolog yjbQ - Bacillus subtilis >...   111  2e-23
pir||D71642 glutathione-regulated potassium-efflux system protei...   111  2e-23
sp|P39830|YBAL_ECOLI HYPOTHETICAL 59.4 KD PROTEIN IN GSK-FSR INT...   106  3e-22
gb|AAK40705.1| Na(+)/H(+) antiporter [Sulfolobus solfataricus]        104  1e-21
pir||C70474 Na+/H+-exchanging protein - Aquifex aeolicus >gi|298...   104  2e-21
pir||B69146 gluthatione-regulated K+/H+ antiporter - Methanobact...   103  4e-21
pir||G75282 probable glutathione-regulated potassium-efflux syst...   102  9e-21
pir||G75431 probable Na+/H+ antiporter - Deinococcus radiodurans...   101  1e-20
pir||G70337 Na+/H+-exchanging protein - Aquifex aeolicus >gi|298...   101  2e-20
sp|P44933|KEFX_HAEIN GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYST...   100  3e-20
dbj|BAA06982.1| (D32253) MagA [Magnetospirillum sp.]                   99  6e-20
pir||A81330 probable glutathione-regulated potassium-efflux syst...    99  8e-20
gb|AAD01191.1| (AF003382) KEA1 [Arabidopsis thaliana]                  99  1e-19
gb|AAF78418.1|AC009273_24 (AC009273) Identical to K efflux antip...    98  2e-19
pir||E82956 probable potassium efflux transporter PA5518 [import...    97  3e-19
gb|AAC60780.1| (U46859) RosB [Yersinia enterocolitica (type 0:8)]      97  4e-19
pir||G69819 Na+/H+ antiporter homolog yhaU - Bacillus subtilis >...    97  4e-19
pir||B82056 glutathione-regulated potassium-efflux system protei...    96  7e-19
dbj|BAB11240.1| (AB010074) potassium/proton antiporter-like prot...    95  1e-18
sp|P03819|KEFC_ECOLI GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYST...    94  2e-18
pir||G64578 glutathione-regulated potassium-efflux system protei...    94  3e-18
pir||T35370 probable transmembrane transport protein - Streptomy...    93  6e-18
pir||C71934 glutathione-regulated potassium-efflux system protei...    92  8e-18
pir||F82595 glutathione-regulated potassium efflux system protei...    92  8e-18
pir||A72473 probable Na+/H+ antiporter APE2426 - Aeropyrum perni...    92  1e-17
sp|P45522|KEFB_ECOLI GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYST...    90  4e-17
pir||C81997 probable glutathione-regulated potassium-efflux syst...    90  4e-17
pir||B81225 glutathione-regulated potassium-efflux system protei...    90  5e-17
pir||T36239 probable integral membrane efflux protein - Streptom...    89  1e-16
gb|AAA84962.1| (U37008) KefC [Myxococcus xanthus]                      88  2e-16
pir||T01227 glutathione-regulated potassium-efflux system protei...    87  3e-16
gb|AAD10158.1| (AC005917) putative potassium/proton antiporter [...    87  3e-16
gb|AAD32281.1|AC006533_5 (AC006533) putative Na+/H+ antiporter [...    87  3e-16
pir||F69201 conserved hypothetical protein MTH760 - Methanobacte...    85  1e-15
pir||T35102 probable transmembrane transport protein - Streptomy...    85  2e-15
gb|AAD30610.1|AC007153_2 (AC007153) similar to Na/H antiporter p...    85  2e-15
pir||F70591 probable kefB protein - Mycobacterium tuberculosis (...    84  3e-15
emb|CAB44437.1| (AJ242913) glutathione-gated K efflux system [Kl...    82  1e-14
emb|CAB76285.1| (AL158057) putative transmembrane transport prot...    82  1e-14
emb|CAC12310.1| (AL445066) Na+/H+ antiporter related protein [Th...    81  2e-14
dbj|BAB10612.1| (AB005243) Na+/H+ antiporter-like protein [Arabi...    80  3e-14
gi|11498844 Na+/H+ antiporter (napA-2) [Archaeoglobus fulgidus] ...    79  1e-13
pir||JC5342 Na+/H+ antiporter cdu2 - Clostridium difficile >gi|1...    76  8e-13
pir||H81265 probable transmembrane transport protein Cj1684c [im...    76  8e-13
pir||H71848 probable na+/h+ antiporter - Helicobacter pylori (st...    75  1e-12
gb|AAK43070.1| Na(+)/H(+) antiporter, putative [Sulfolobus solfa...    74  3e-12
sp|P52071|YPH1_METEX HYPOTHETICAL PROTEIN IN PHAC 3'REGION (ORF1...    73  4e-12
pir||G64667 NA+/H+ antiporter - Helicobacter pylori (strain 2669...    73  4e-12
pir||T51790 hypothetical protein F28D10_120 - Arabidopsis thalia...    73  4e-12

>pir||C75016 na+/h+ antiporter (napa-3) PAB1247 - Pyrococcus abyssi  (strain
           Orsay) >gi|5459083|emb|CAB50569.1| (AJ248288) Na+/H+
           antiporter (napA-3) [Pyrococcus abyssi]
           Length = 380
           
 Score =  717 bits (1831), Expect = 0.0
 Identities = 380/380 (100%), Positives = 380/380 (100%)

Query: 1   MEVFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELG 60
           MEVFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELG
Sbjct: 1   MEVFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELG 60

Query: 61  VVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVL 120
           VVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVL
Sbjct: 61  VVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVL 120

Query: 121 TATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEI 180
           TATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEI
Sbjct: 121 TATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEI 180

Query: 181 ILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGIT 240
           ILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGIT
Sbjct: 181 ILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGIT 240

Query: 241 GAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLI 300
           GAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLI
Sbjct: 241 GAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLI 300

Query: 301 AVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVT 360
           AVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVT
Sbjct: 301 AVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVT 360

Query: 361 MVVITTLITPFLLKWAFSKG 380
           MVVITTLITPFLLKWAFSKG
Sbjct: 361 MVVITTLITPFLLKWAFSKG 380


>pir||H71455 probable Na+/H+-exchanging protein - Pyrococcus horikoshii
           >gi|3256692|dbj|BAA29375.1| (AP000001) 380aa long
           hypothetical Na(+)/H(+) antiporter [Pyrococcus
           horikoshii]
           Length = 380
           
 Score =  631 bits (1611), Expect = e-180
 Identities = 319/380 (83%), Positives = 358/380 (93%)

Query: 1   MEVFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELG 60
           M V LELAIILV+AK+FGYL V+LGFPAALGQL+GG+IIGPSLL++VEY  EVR L+ELG
Sbjct: 1   MNVLLELAIILVVAKLFGYLMVKLGFPAALGQLIGGIIIGPSLLNIVEYSQEVRFLAELG 60

Query: 61  VVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVL 120
           V++LLFLAGLETDVEEFKHVGLSAFIVA MGVFVPFLLGYL+++++GY SL ALF GG+L
Sbjct: 61  VIILLFLAGLETDVEEFKHVGLSAFIVATMGVFVPFLLGYLIAIVYGYRSLAALFLGGIL 120

Query: 121 TATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEI 180
           TATSVGLTTSILM+MKKLRTKVGTTILAAAIVDDVLGI+ILT+LVAMSSRG+VE+ DIEI
Sbjct: 121 TATSVGLTTSILMEMKKLRTKVGTTILAAAIVDDVLGIIILTILVAMSSRGRVEIFDIEI 180

Query: 181 ILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGIT 240
           IL EV IFF+LGI IGHP+VKEVL LSE+ITLPETVTTFAIVIML+FAYLAEKFQLAGIT
Sbjct: 181 ILAEVIIFFLLGIFIGHPIVKEVLMLSEKITLPETVTTFAIVIMLLFAYLAEKFQLAGIT 240

Query: 241 GAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLI 300
           GAYLAGLLVSM+EGS+K+TDK+MTIGYSLFIPIFLVSIGIETDI+VL  AGVFA+VYSLI
Sbjct: 241 GAYLAGLLVSMSEGSKKVTDKMMTIGYSLFIPIFLVSIGIETDIKVLATAGVFAIVYSLI 300

Query: 301 AVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVT 360
           A++GKI GCGFGALV +FKP EA+QVGIGMIPRMEVALIIANVGLKEGILTRG LA+PVT
Sbjct: 301 AIIGKIQGCGFGALVTKFKPAEALQVGIGMIPRMEVALIIANVGLKEGILTRGTLAIPVT 360

Query: 361 MVVITTLITPFLLKWAFSKG 380
           MVV+TTL+TPFLLK AFS+G
Sbjct: 361 MVVVTTLVTPFLLKLAFSRG 380


>pir||F71234 probable Na+/H+-exchanging protein - Pyrococcus horikoshii
           >gi|3256522|dbj|BAA29205.1| (AP000001) 375aa long
           hypothetical Na(+)/H(+) antiporter [Pyrococcus
           horikoshii]
           Length = 375
           
 Score =  318 bits (806), Expect = 7e-86
 Identities = 168/375 (44%), Positives = 245/375 (64%), Gaps = 7/375 (1%)

Query: 1   MEVFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELG 60
           ME  L LAI+L +AK  G++  +   P  LGQ+L G+++G     ++E    +   + LG
Sbjct: 1   METLLLLAILLAVAKFSGWIFEKFNQPIVLGQILAGILMGL----IIERNEIIIEFANLG 56

Query: 61  VVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSV-LHGYGSLKALFFGGV 119
           V+MLLFLAG+E+D+EEFK VG    +VA +GV   F+ G++V+     +G+  A+ +G V
Sbjct: 57  VLMLLFLAGIESDLEEFKKVGKPGILVAGVGVLFAFIFGFIVAYPFFDFGT--AMLYGAV 114

Query: 120 LTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIE 179
           +T TSV +T  +LM++ KLRT+ GTTILAAA++DDVLGI++LT++++    G V  + I 
Sbjct: 115 MTPTSVSITVKVLMELGKLRTREGTTILAAAVIDDVLGILVLTIVISTLREGSVHYDIIL 174

Query: 180 IILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGI 239
            ILLEVA F  + + IG   +++      +I LPE  TTFA+V +++FAYLAE   LA I
Sbjct: 175 KILLEVAGFLAVFLYIGPVFMEDAFRRLSKIDLPEATTTFAVVFLVLFAYLAEHLNLASI 234

Query: 240 TGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSL 299
            GAYL GL +  T   ++I D + T+GYS+FIP+F V +G+  D R L  A VFAL+Y+L
Sbjct: 235 LGAYLIGLSIGQTSYKKRIEDHMNTLGYSIFIPLFFVDVGMRIDPRFLLQAKVFALLYAL 294

Query: 300 IAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPV 359
           IA++ K+IGCG GA +A F    ++++GIGMIPR+ V L +    +  GI     L V +
Sbjct: 295 IAMLSKVIGCGLGAYLANFDWKSSLKIGIGMIPRLGVELAMITTAMASGIAGSDVLTVAM 354

Query: 360 TMVVITTLITPFLLK 374
           TMV +TTL+TP LLK
Sbjct: 355 TMVFLTTLVTPLLLK 369


>pir||C75201 na+/h+ antiporter (napa-1) PAB0084 - Pyrococcus abyssi  (strain
           Orsay) >gi|5457567|emb|CAB49058.1| (AJ248283) Na+/H+
           antiporter (napA-1) [Pyrococcus abyssi]
           Length = 375
           
 Score =  312 bits (790), Expect = 6e-84
 Identities = 165/375 (44%), Positives = 245/375 (65%), Gaps = 7/375 (1%)

Query: 1   MEVFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELG 60
           ME  L LA++L +AK+ G++  R   P  LGQ++ GVI+G     ++E    +   + LG
Sbjct: 1   METLLMLALMLAVAKLSGWVFERFNQPIVLGQIIAGVIMGL----LIERNEIIVEFANLG 56

Query: 61  VVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSV-LHGYGSLKALFFGGV 119
           V+MLLFLAGLE+D EEFK VG  + +VA +GV   FL G+L++     +G+  AL +G +
Sbjct: 57  VLMLLFLAGLESDFEEFKRVGRPSILVASVGVLFAFLFGFLIAYPFFDFGT--ALLYGAI 114

Query: 120 LTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIE 179
           +T TSV +T  +LM++ KLRTK G TILAAA+VDDVLGI+ILT++++M   G V  + I 
Sbjct: 115 MTPTSVSITVKVLMELGKLRTKEGATILAAAVVDDVLGILILTIVISMLREGSVHYDVIV 174

Query: 180 IILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGI 239
            +LLEVA F  + + +G  +++ V     ++ LPE+ T+FAIV +++FAYLAE   LA I
Sbjct: 175 EVLLEVAGFLAVFLYLGPVVMENVFRRLSKVDLPESTTSFAIVFLVLFAYLAEHLNLASI 234

Query: 240 TGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSL 299
            GAYL GL +  T   ++I   +  IGYS+FIP+F V +G+  D R L  A  FA +Y++
Sbjct: 235 LGAYLIGLSIGQTSYKKRIEGPMNVIGYSIFIPVFFVEVGMRIDPRFLFEAKTFAFLYAV 294

Query: 300 IAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPV 359
            A++ K+IGCG GA +++F    +I++GIGMIPR+ V L + +  +  G+     L V +
Sbjct: 295 FAMISKVIGCGLGAYLSKFDWRTSIKIGIGMIPRLGVELAMISTAMAAGVAGSDVLTVAM 354

Query: 360 TMVVITTLITPFLLK 374
           TMV +TTLITP +L+
Sbjct: 355 TMVFLTTLITPIMLR 369


>gb|AAB40041.1| (U17283) putative spore germination apparatus protein [Bacillus
           megaterium] >gi|1589214|prf||2210362A grmA gene
           [Bacillus megaterium]
           Length = 386
           
 Score =  277 bits (700), Expect = 2e-73
 Identities = 152/375 (40%), Positives = 231/375 (61%), Gaps = 2/375 (0%)

Query: 1   MEVFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELG 60
           ME  L LA+IL   KI G+LSVRLG P+ LG+LL G+I+GP++L  +     V   SE+G
Sbjct: 1   MEFVLSLALILFATKIAGHLSVRLGQPSVLGKLLIGIILGPAVLGWIHNDQFVHYFSEIG 60

Query: 61  VVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVL 120
           V++L+FLAGLETD+E+ K    +AF VAV+G+ +PF+ G+ V  L G G+  +LF G +L
Sbjct: 61  VLLLMFLAGLETDLEQLKRNWKAAFAVAVLGIILPFIGGFGVGELFGLGATYSLFIGVLL 120

Query: 121 TATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEI 180
            ATSV +T  +L DM +L ++ G+TIL AA+VDDVL +V+L ++++    G  E   + +
Sbjct: 121 CATSVSITVQVLKDMNRLNSREGSTILGAAVVDDVLVVVLLAIMISFLGTG--EEVSLGL 178

Query: 181 ILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGIT 240
           ++ +  IFFI  +L G  +V +VL     + + E V +  + I   + Y A+   +AGI 
Sbjct: 179 LVGKKLIFFIGAVLAGWLVVPKVLDWLTNLKVTEPVVSIGLAICFGYVYFADLMGMAGII 238

Query: 241 GAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLI 300
           GA+ AG+ +S T     I  K+  I Y++F+P+F VSIG+      +     F L+ S+I
Sbjct: 239 GAFAAGIAISQTSYRHTIESKVEPIAYAVFVPVFFVSIGLNVSFEGVGDQIGFILLLSVI 298

Query: 301 AVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVT 360
           AV+ K++G   GA V  F    ++ +G GM+ R EVALIIA  GL+E +L        V 
Sbjct: 299 AVITKLVGGALGAKVTGFSTRSSLLIGSGMVSRGEVALIIAATGLQESLLLPEYFTSAVI 358

Query: 361 MVVITTLITPFLLKW 375
           +++ITTL+ P L+K+
Sbjct: 359 VIIITTLVAPPLIKY 373


>gb|AAF91326.1|AF246294_2 (AF246294) GerN [Bacillus cereus]
           Length = 387
           
 Score =  269 bits (681), Expect = 3e-71
 Identities = 146/376 (38%), Positives = 234/376 (61%), Gaps = 3/376 (0%)

Query: 2   EVFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGV 61
           E F ++A+IL+  K+ G LSVRLG P+ LG+L+ G++IGP++L  +E    +  LS +GV
Sbjct: 4   EFFFQIALILLSTKLAGDLSVRLGQPSVLGKLIVGIVIGPAVLGWIENSELLTQLSNVGV 63

Query: 62  VMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLT 121
           ++L+F+AGLETD+EE      S+  VA+ G+ +PF+ GY+  ++ G     A+F G +L 
Sbjct: 64  ILLMFMAGLETDLEELNANRNSSLAVALGGIILPFVGGYVSGLVMGMEQGNAVFLGLLLC 123

Query: 122 ATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEII 181
           ATSV ++   L D+ K++T+  TT+L AA+ DD+L  V++ L  AMS  G  +V ++ ++
Sbjct: 124 ATSVSISVQTLRDLGKMKTRESTTMLGAAVFDDIL--VVILLAFAMSFLGTDDV-NLTMV 180

Query: 182 LLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGITG 241
           +L+  +FF   ILIG   V  ++     + + E++ + A++I   FAY  E   +AGI G
Sbjct: 181 ILKKVVFFASIILIGWKGVPAIMRWLSPLRVSESIVSAALIICFSFAYFGELLGIAGIIG 240

Query: 242 AYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLIA 301
           A+ AG+ +S T    ++  K+  I Y++F+P+F VSIG+      + +   F L  ++IA
Sbjct: 241 AFAAGIAISQTNYKHEVEKKVEPIAYAMFVPVFFVSIGMNITFDGIGNQIWFILALTVIA 300

Query: 302 VVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVTM 361
           V+ K+IGCGFGA +  F    +  +G GM+ R EVALIIA  GL  G+L +      V +
Sbjct: 301 VLTKLIGCGFGARMTGFDAKSSAIIGAGMVSRGEVALIIAGTGLSSGLLAQDYFTAIVIV 360

Query: 362 VVITTLITPFLLKWAF 377
           V++TT+ITP +LK+ F
Sbjct: 361 VILTTMITPPMLKYTF 376


>sp|P26235|NAPA_ENTHR NA(+)/H(+) ANTIPORTER >gi|282287|pir||A42111 Na+/H+-exchanging
           protein NapA - Enterococcus hirae
           >gi|148316|gb|AAA24781.1| (M81961) NaH-antiporter
           protein [Enterococcus hirae]
           Length = 383
           
 Score =  236 bits (596), Expect = 3e-61
 Identities = 128/379 (33%), Positives = 221/379 (57%)

Query: 1   MEVFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELG 60
           ME    L +ILV   I  ++S R G PA +GQLL GV++G + L  V     V   SE+G
Sbjct: 1   MEFIGILCLILVATTIGSHISRRFGIPAVIGQLLVGVLLGQAGLGWVHPNILVHDFSEIG 60

Query: 61  VVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVL 120
           V++L+FLAGLE+D+   K        VA++G+  P   G+L        + +A+FFG +L
Sbjct: 61  VILLMFLAGLESDLSLLKKYFKPGMFVALLGILFPVFFGWLTGEAFQVANNEAIFFGIIL 120

Query: 121 TATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEI 180
            ATSV ++  +L ++  + TK G+TIL A++VDD+L +++L+  ++  +        + +
Sbjct: 121 AATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLVLSFSLSFLTGKSTSNLPLPL 180

Query: 181 ILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGIT 240
           +LLE   +F+   L+   +   +++L+E+I     +   ++VI L  +YLA+   L+ + 
Sbjct: 181 LLLEQLFYFLFIFLLVKWIAPFLMSLAEKIYANSAIIIMSLVICLGMSYLADLIGLSSVI 240

Query: 241 GAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLI 300
           GA+ AG+ VS T+   ++ + +  +GY++FIP+F VS+G+E D    +   +F L+ +L+
Sbjct: 241 GAFFAGIAVSQTKVKHEVYNNVEALGYAVFIPVFFVSVGLEVDFSKFSEQILFILILTLV 300

Query: 301 AVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVT 360
           A++ K+IG   GA  + F    A+ VG GMI R E+ALII  +G +  ++     +  V 
Sbjct: 301 AILTKLIGGYIGAKFSSFSSNSALMVGAGMISRGEMALIILQIGQQSNLIENHYYSPLVI 360

Query: 361 MVVITTLITPFLLKWAFSK 379
           +V+++TLI+P +LK+   K
Sbjct: 361 VVLLSTLISPLILKYFTKK 379


>emb|CAA51756.1| (X73329) Na/H antiporter homolog [Lactococcus lactis]
           Length = 379
           
 Score =  234 bits (591), Expect = 1e-60
 Identities = 129/379 (34%), Positives = 215/379 (56%), Gaps = 3/379 (0%)

Query: 1   MEVFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELG 60
           M   L+L I+L+ + I    S RL  PA +GQ+L G++I PS+L +V  G  + ++SE+G
Sbjct: 1   MNDILQLTIVLIASLIATLASRRLKIPAVIGQMLVGILIAPSVLGLVHSGHVLEVMSEIG 60

Query: 61  VVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVL 120
           V++L+FLAGLE+D+   K    ++ +VA+ GV VP ++  LV+   GYG   + F+G V 
Sbjct: 61  VILLMFLAGLESDLTVLKKNFKASMLVAIGGVIVPLIVFGLVAFSFGYGMSTSFFYGIVF 120

Query: 121 TATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEI 180
            ATSV +T  +L +  KL T+ G+ IL AA+VDD+L ++IL++  +  + G       + 
Sbjct: 121 AATSVSITVEVLQEYGKLSTRAGSIILGAAVVDDILAVLILSIFTSFKNGGSGTHLFFQF 180

Query: 181 ILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGIT 240
           +L    + F   + + H L+       +++ +    T  A++I L  + LA+   ++ + 
Sbjct: 181 LL---ELLFFAFLFVVHKLIPRFWKFVQKLPIANKNTIVALIICLGLSLLADSVGMSAVI 237

Query: 241 GAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLI 300
           G++ AGL +S TE S KI +    IGY +FIP+F V I I      L H     L+++L+
Sbjct: 238 GSFFAGLAISQTEVSHKIEEYTSAIGYVIFIPVFFVLIAISVQFDSLIHHPWIILLFTLL 297

Query: 301 AVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVT 360
           A++ K I   F     +    E++ +G GMI R E+ALI+A +GL   I+T    +  V 
Sbjct: 298 AILTKFIPAYFVGKSNKLSTGESMLIGTGMISRGEMALIVAQIGLTSAIITDEVYSELVI 357

Query: 361 MVVITTLITPFLLKWAFSK 379
           ++++ T++ PFL+K    K
Sbjct: 358 VIILATVLAPFLIKLVLKK 376


>pir||B71038 probable Na+/H+-exchanging protein - Pyrococcus horikoshii
           >gi|3258023|dbj|BAA30706.1| (AP000006) 425aa long
           hypothetical Na(+)/H(+) antiporter [Pyrococcus
           horikoshii]
           Length = 425
           
 Score =  234 bits (590), Expect = 2e-60
 Identities = 143/404 (35%), Positives = 228/404 (56%), Gaps = 35/404 (8%)

Query: 3   VFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIG---------PSLLDVVEYGSEV 53
           +   +   ++IAKI   +  R   P  LG+LL G+ +G            L +    SEV
Sbjct: 6   ILFTIGTAIIIAKIGDSIVERFELPGVLGELLMGMALGNLVYFGLIKSEYLPITMGSSEV 65

Query: 54  -RLLSELGVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLK 112
              L++LG+++LLFL  L+TD+E+ K  G++A +  +MGVFVP  LGY    + GYG  +
Sbjct: 66  IDFLAKLGIILLLFLGALDTDIEKLKRTGVTAVVSTIMGVFVPLALGYYALRVMGYGYRE 125

Query: 113 ALFFGGVLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGK 172
           A   G +LTATS+GLT  I+MD+  LR++VG   L+A+++DD LGI +  ++ A+ S   
Sbjct: 126 AFAGGVLLTATSIGLTVRIMMDLGALRSEVGAASLSASVIDDFLGIAL--IIFAVGSGSL 183

Query: 173 VEVEDIEIILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAE 232
           +E+        ++ +FFI+  ++G  LV   +  +E++ + + V    I +M IFA LAE
Sbjct: 184 LELS------AKIIVFFIITGVLGWYLVDHYIKFAEKLHVEKGVLGLVIGLMFIFAALAE 237

Query: 233 KFQLAGITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGV 292
            +  A I G+++AGL++S     ++I +++ +IGY   IP+F V  G   ++ V  +   
Sbjct: 238 DWFAAAIEGSFMAGLILSKLPEGKRIMEEVRSIGYGFLIPLFFVHTGAMLNLTVFKNIEA 297

Query: 293 FALVYSL--IAVVGKIIGCGFGA-----------LVARFKPIEAIQVGIGMIPRMEVALI 339
           F L + L  IAVVGK+IG GFGA           L  +     ++Q+GIG IPR EVAL+
Sbjct: 298 FKLAFVLTTIAVVGKVIGRGFGAWLTAWGRGRGFLFTKQNFRMSLQMGIGSIPRTEVALV 357

Query: 340 IANVGLKEGILTRGD----LAVPVTMVVITTLITPFLLKWAFSK 379
              V +  G ++ G+    +A  +  + ++ LITP LLKWAF +
Sbjct: 358 DLMVAIHGGAISSGNVPKFIAATLIFITVSVLITPPLLKWAFKE 401


>pir||C75176 na+/h+ antiporter (napa-2) PAB0390 - Pyrococcus abyssi  (strain
           Orsay) >gi|5458000|emb|CAB49490.1| (AJ248284) Na+/H+
           antiporter (napA-2) [Pyrococcus abyssi]
           Length = 426
           
 Score =  230 bits (580), Expect = 2e-59
 Identities = 140/402 (34%), Positives = 224/402 (54%), Gaps = 35/402 (8%)

Query: 3   VFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIG---------PSLLDVVEYGSEV 53
           +   + + L++AKI   +  R   P  LG+L+ G+++G            L +    SEV
Sbjct: 7   ILFTIGVALILAKIGDAIIERFELPGVLGELIMGMLLGNLVYFGIVSKDYLPITMGSSEV 66

Query: 54  -RLLSELGVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLK 112
              L++LG++ LLFL  L+TDVE+ K  GL+A I  +MGVFVP +LGY      GY   +
Sbjct: 67  IDFLAKLGIIFLLFLGALDTDVEQLKKTGLTATISTLMGVFVPLILGYFALRYMGYSHRE 126

Query: 113 ALFFGGVLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGK 172
           A   G +LTATS+GLT  ++MD+  LR++VG   L+A+++DD LGI ++   V   S   
Sbjct: 127 AFAGGVLLTATSIGLTVRVMMDLGVLRSEVGAASLSASVMDDFLGIALIIFAVGSGS--- 183

Query: 173 VEVEDIEIILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAE 232
                +  + +++  FFI+  ++G   + + +  +ER+ + + +   A+ +M +FA LAE
Sbjct: 184 -----LLGLSMKIIAFFIITGILGWYSIDKYIRFAERLHVEKGILGMAVGMMFLFAALAE 238

Query: 233 KFQLAGITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGV 292
            +  A I G+++ GL++S     ++I +++ +IGY L IPIF +  G   ++ V  +A  
Sbjct: 239 GWFAAAIEGSFMMGLILSKLPEGKRIMEEVRSIGYGLLIPIFFIHTGAMLNLTVFRNADA 298

Query: 293 --FALVYSLIAVVGKIIGCGFGA-----------LVARFKPIEAIQVGIGMIPRMEVALI 339
              ALV S IAV+GK+ G GFGA           L  R     ++Q+GIG IPR EVAL+
Sbjct: 299 IKLALVLSTIAVIGKVAGRGFGAWITAWGRGRDFLFTRENFKMSLQMGIGSIPRTEVALV 358

Query: 340 IANVGLKEGILTRGD----LAVPVTMVVITTLITPFLLKWAF 377
              V +  G ++  D    +A  +  + ++ LITP LLKWAF
Sbjct: 359 DLMVAIHGGAISPDDVPKFIAATLIFITVSVLITPPLLKWAF 400


>pir||S74414 Na+/H+-exchanging protein sll0689 - Synechocystis sp.  (strain PCC
           6803) >gi|1001188|dbj|BAA10332.1| (D64001)
           NaH-antiporter protein [Synechocystis sp.]
           Length = 461
           
 Score =  218 bits (550), Expect = 8e-56
 Identities = 129/417 (30%), Positives = 223/417 (52%), Gaps = 46/417 (11%)

Query: 3   VFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEY------------- 49
           V L L +I   +K+ G + +RL  P  LG+L+GGV++G S L ++ +             
Sbjct: 32  VLLSLVVIYFASKLGGEVCLRLNLPPVLGELVGGVLVGVSALKLLLFPEGGLAPEDSLVI 91

Query: 50  ---------------------GSEVRLLSELGVVMLLFLAGLETDVEEFKHVGLSAFIVA 88
                                   + ++SELGV++LLF  GLE++++E   VG  A IVA
Sbjct: 92  QLLMGSADLSPEAAQSVFSAQSEVISVISELGVIILLFEIGLESNLKELIRVGPQAAIVA 151

Query: 89  VMGVFVPFLLGYL-VSVLHGYGSLKALFFGGVLTATSVGLTTSILMDMKKLRTKVGTTIL 147
           V+GV  PF LG + +  + G  ++ A+F G  LTATS+G+T  +L ++ +L +  G  I+
Sbjct: 152 VVGVVTPFSLGTIGLMTIFGVAAIPAIFAGAALTATSIGITAKVLAEINRLSSNEGQIII 211

Query: 148 AAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIILLEVAIFFILGILIGHPLVKEVLTLS 207
            AA++DD+LGI++L ++ ++   G++++ +I  ++L    F +  ILIG  L    ++L 
Sbjct: 212 GAAVLDDILGIIVLAVVGSLVKTGEIQISNIIYLILSATGFVVGSILIGRLLSPFYVSLV 271

Query: 208 ERITLPETVTTFAIVIMLIFAYLAEKFQLAGITGAYLAGLLVSMTEGSRKITDKIMTIGY 267
            R+     +   +I +  + +Y+A+  QL  I G++ AGL+++ TE    + ++I+ +  
Sbjct: 272 NRMKTRGQLLLVSICVAFVLSYIAQIVQLEAILGSFAAGLILAETEKREDLEEQILPLA- 330

Query: 268 SLFIPIFLVSIGIETDIRVLTHAG-------VFALVYSLIAVVGKIIGCGFGALVARFKP 320
             F+P+F V +G +TD+ VL  A        + A    L+A+VGK++    G  +     
Sbjct: 331 DFFVPVFFVCVGAKTDVSVLNPAVPANREGLIIAAFLILVAIVGKVV---TGFTLFGKSE 387

Query: 321 IEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVTMVVITTLITPFLLKWAF 377
           +  + +G+GMIPR EV L+ A VG   G L     A  + MV++TT + P  L+  F
Sbjct: 388 LNKLAIGVGMIPRGEVGLVFAGVGAASGALDPATDAAIIVMVIVTTFVAPPWLRAVF 444


>pir||E70380 Na+/H+-exchanging protein - Aquifex aeolicus
           >gi|2983453|gb|AAC07034.1| (AE000714) Na(+)/H(+)
           antiporter [Aquifex aeolicus]
           Length = 408
           
 Score =  213 bits (537), Expect = 3e-54
 Identities = 125/385 (32%), Positives = 207/385 (53%), Gaps = 13/385 (3%)

Query: 3   VFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVV 62
           +FL LAI+L  AK+FG +  +LG P  LG++  GVI+G S+L ++     +++L+ELGV+
Sbjct: 18  LFLHLAILLFSAKLFGSIFRKLGIPPVLGEVTAGVILGQSVLGLIPLSEAIKVLAELGVI 77

Query: 63  MLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVS-VLHGYGSLKALFFGGVLT 121
           +LLF  GLE D+     VGL + +VA++G  +PF  G++VS    G   + +LF GG LT
Sbjct: 78  LLLFEVGLEADINMLMRVGLWSTLVAIVGAALPFAGGFIVSYYFFGLDLVASLFMGGALT 137

Query: 122 ATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEII 181
           ATS+G+T  +L D+ K + +    +L AA++DD++G++IL  L   S    V  +    +
Sbjct: 138 ATSIGITVRVLTDLNKHKERFAQIVLGAAVLDDIMGVIILAALYEFSKTKAVHFDTTVNL 197

Query: 182 LLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGITG 241
           ++ + +FF++   + + L K +   + +    + +    + ++L+ AY A KF    I G
Sbjct: 198 IIHILMFFLIAPFVANVLAKLLSIAARKTQDMDLIPASIMALILLAAYSAHKFGSPSILG 257

Query: 242 AYLAGLLVS---------MTEGSRKITDKI---MTIGYSLFIPIFLVSIGIETDIRVLTH 289
           ++ AGL +S         M     K+  K+   +T    +  PIF VS+G+  +++ +  
Sbjct: 258 SFTAGLALSRRFVIPFAAMLRLDEKLLHKVEESITPLVWVMAPIFFVSVGLALNLKAIDF 317

Query: 290 AGVFALVYSLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGI 349
           +      +S   +V  IIG      VA     E   +G  M+PR EV LI A  G     
Sbjct: 318 SSPEFWTFSSALIVVAIIGKVLAGFVAPGSLKEKASIGFSMLPRGEVGLIFAEFGRSFKA 377

Query: 350 LTRGDLAVPVTMVVITTLITPFLLK 374
           +   + AV V +V +TTLI P +LK
Sbjct: 378 INEVEYAVIVFVVAVTTLIAPIVLK 402


>pir||C75103 na+/h+ antiporter (napa-4) PAB0809 - Pyrococcus abyssi  (strain
           Orsay) >gi|5458640|emb|CAB50128.1| (AJ248286) Na+/H+
           antiporter (napA-4) [Pyrococcus abyssi]
           Length = 390
           
 Score =  172 bits (432), Expect = 5e-42
 Identities = 106/392 (27%), Positives = 205/392 (52%), Gaps = 17/392 (4%)

Query: 1   MEVFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELG 60
           M    +L+I+LV+AK   +L  + G    +  +L G+I+GP  L +V+   E+++L E G
Sbjct: 1   MNYIFDLSILLVVAKSLEWLLKKRGVHPIIAHILTGIILGPFGLAIVKPSEELKVLGEFG 60

Query: 61  VVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVL 120
           ++M++   GL ++        + A IVA +GV   F+LG+          + ALF G  L
Sbjct: 61  LIMMMLYMGLTSNFSAISRNKVKATIVATLGVAFSFILGFSTVYFIERNMIAALFVGITL 120

Query: 121 TATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEI 180
             T++ +T+ +L+  ++++ ++ + ++ AA  DD++ + ++ LL  + ++G   +  + +
Sbjct: 121 GNTAIEVTSGVLV-RERVKKEISSVLMGAAFADDIIAVYLIGLLTGI-TQGSFSLYPMVV 178

Query: 181 ILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGIT 240
           + +++ +F +  +LI   + K        +       TF I++  + A+LAE   L  I 
Sbjct: 179 LTIKIVVFIVATLLISEFVFKRSARFYNVVKDLHVFFTFTIILTFMLAFLAEDIGLNQII 238

Query: 241 GAYLAGLLVSMTEGSR-----------KITDKIMTIGYSLFIPIFLVSIGI--ETDIRVL 287
           GAYLAGL +S     +           ++  ++  +    FIP+F + +G+  + ++R +
Sbjct: 239 GAYLAGLTISRLRERKDPMVITRIKLNELISELEVVLLEFFIPLFFIYVGLMFQPNVREI 298

Query: 288 THAGVFALVYSLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKE 347
           +   + AL+Y L A++GK+IGCG G L+      +AI VG+GM  R  + L I  +GL++
Sbjct: 299 S-VLMIALLY-LAAILGKLIGCGLGMLLFGSSLRDAIIVGVGMGGRGSLELAILKLGLEK 356

Query: 348 GILTRGDLAVPVTMVVITTLITPFLLKWAFSK 379
           G++     A  V + ++T L TP   +    K
Sbjct: 357 GLINESLFATIVIVSMLTALSTPIFFRGVIRK 388


>pir||H71083 probable Na+/H+-exchanging protein - Pyrococcus horikoshii
           >gi|3257347|dbj|BAA30030.1| (AP000004) 390aa long
           hypothetical Na(+)/H(+) antiporter [Pyrococcus
           horikoshii]
           Length = 390
           
 Score =  172 bits (431), Expect = 7e-42
 Identities = 112/392 (28%), Positives = 201/392 (50%), Gaps = 17/392 (4%)

Query: 1   MEVFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELG 60
           M    +L+I+LV+AK   +L  + G    +  +L G+I+GP  L +V   SE+++L E G
Sbjct: 1   MSYIFDLSILLVVAKSLEWLLKKKGIHPIIAHILTGIILGPFGLSIVLPTSELKVLGEFG 60

Query: 61  VVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVL 120
           ++M++   GL ++        + A +VA+ GV   F+LG+L         + ALF G  L
Sbjct: 61  LIMMMLYMGLTSNFSAISRNKVKASVVAMFGVAFSFILGFLTVYFLEKSLIAALFVGITL 120

Query: 121 TATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEI 180
             T++ +T+ +L+  ++++  + + ++ AA  DD++ + ++ +L  ++  G   +  + +
Sbjct: 121 GNTAIEVTSGVLV-RERVKKDISSVLMGAAFADDIIAVYLIGILTGITQGG---ISGLSL 176

Query: 181 ILLEVAI-FFILGILIGHPLV-KEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAG 238
           + L + I  FILG+L+    V K        I       TF IV+    A++A+   L  
Sbjct: 177 VFLTIKIVIFILGVLMLSEFVFKRSTRFYNIIRDLHIFFTFTIVLTFTLAFIAQDIGLNQ 236

Query: 239 ITGAYLAGLLVSMTEGSR-----------KITDKIMTIGYSLFIPIFLVSIGIETDIRVL 287
           I GAYLAGL +S     +           ++ +++  +    FIP+F V +G+  +  V 
Sbjct: 237 IIGAYLAGLTISRLRERKDPMVITRIKLNELIEELEIVLVEFFIPLFFVYVGLMFNPNVR 296

Query: 288 THAGVFALVYSLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKE 347
             + +  L+    AV+GK+IGCG G  +      +AI VGIGM  R  + L I  +GL++
Sbjct: 297 DISILLILLLYASAVLGKLIGCGLGMKIFGSSIRDAIIVGIGMGGRGSLELAILKLGLEK 356

Query: 348 GILTRGDLAVPVTMVVITTLITPFLLKWAFSK 379
           G++  G  A  V + ++T L TP L ++   K
Sbjct: 357 GLIDEGIFATVVIVSMLTALSTPVLFRYTVRK 388


>pir||F70155 Na+/H+ antiporter (napA) homolog - Lyme disease spirochete
           >gi|2688368|gb|AAC66821.1| (AE001150) Na+/H+ antiporter
           (napA) [Borrelia burgdorferi]
           Length = 701
           
 Score =  170 bits (427), Expect = 2e-41
 Identities = 124/402 (30%), Positives = 208/402 (50%), Gaps = 36/402 (8%)

Query: 5   LELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSL-----------LDVVEYGS-- 51
           + LAII++ +   G L  ++G P  +GQ+  G+I+ P+            L + + G   
Sbjct: 36  MSLAIIVISSISIGNLVAKIGIPKVIGQITAGIILSPNAFGKIQIPLLFPLGITQIGENY 95

Query: 52  ----EVRLLSELGVVMLLFLAGLETDVE---EFKHVGLSAFIVAVMGVFVPFLLGYLVSV 104
               ++  +S +  ++LLF AGLETD++   +F   G    I  V+G F  F+L  + S+
Sbjct: 96  LINEKIFAISTIASIILLFTAGLETDLKLFIKFLPRGGIIGITEVVGTFTSFVL--MASI 153

Query: 105 LHGYGSLK--ALFFGGVLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILT 162
           +     +   +LF G + T TS G+  SIL   KK+ T  G TI++ +I+DDVL +++LT
Sbjct: 154 IFNVPLISPTSLFIGIIGTPTSAGIAASILSAKKKMSTSEGVTIISTSIIDDVLSMLMLT 213

Query: 163 LLVAMSSRGKVEVEDIEIILLEVAIF--FILGILIGHPLVKEVLTLSERITLPETVTTFA 220
            ++ +S      + D++I     AI    ++ + +   L+    TLS  +    +VT   
Sbjct: 214 SVITISR----SISDLDIASSIKAIVQNIVIWLCLTFSLIYISETLSRLLKKLNSVTLAT 269

Query: 221 IVIMLIFAYLAEKFQLAG---ITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVS 277
           ++ + +   +A  FQ  G   + GAY+ GL +S T+    I DK+ TI    FIPIF  S
Sbjct: 270 VITLSLALTIASIFQNLGMSFVVGAYVFGLAMSKTDIVYVIQDKL-TIFERFFIPIFFTS 328

Query: 278 IGIETDIRVLTHAGVF--ALVYSLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRME 335
           IG+ +DI  +    V    L  S IA++ K I C   AL   F  + A+++  GM+PR E
Sbjct: 329 IGLMSDINEILSKEVLILGLAISAIAIITKSIFCFIPALFLGFNKLGALKIATGMVPRGE 388

Query: 336 VALIIANVGLKEGILTRGDLAVPVTMVVITTLITPFLLKWAF 377
           V+LI+ANV L  G +++    + + MV + T+I   ++ + F
Sbjct: 389 VSLIMANVALSSGFISQKIFGIIIIMVFLPTIIATPIINFLF 430


>pir||B64459 Na+/H+-exchanging protein - Methanococcus jannaschii
           >gi|1591911|gb|AAB99281.1| (U67568) NA(+)/H(+)
           antiporter (napA) [Methanococcus jannaschii]
           Length = 388
           
 Score =  169 bits (423), Expect = 6e-41
 Identities = 108/375 (28%), Positives = 203/375 (53%), Gaps = 12/375 (3%)

Query: 9   IILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVMLLFLA 68
           IIL I  I   L  +   PA    ++ G+IIGP  L++++    +++L++ G +ML+FLA
Sbjct: 10  IILSIIFIVPNLLKKFNIPAITSIMIAGIIIGPYGLNILQVDETLKILADFGAIMLMFLA 69

Query: 69  GLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTATSVGLT 128
           GLE D E  K    ++ I+++  + +P + GYL+    G G + +L +  +  + SV + 
Sbjct: 70  GLEVDNETLKQEFKNSLILSLFSLLIPGVGGYLIGQYLGLGFIGSLLYAVIFASHSVAIV 129

Query: 129 TSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIILLEVAIF 188
            +IL ++K ++T++GT IL+A I+ D+  +++L++++ +   G    E++   LLE  ++
Sbjct: 130 YAILEELKMVKTRLGTIILSATIIVDLFTLLLLSVVIKLGIGG----ENVGTFLLETVLY 185

Query: 189 FILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGITGAYLAGLL 248
             + +L    L K +L + E++        + + I+ I   + E   +  I GA++ G+ 
Sbjct: 186 IGVLLLAIPSLSKNILGVFEKLHAQR--IHYVLFIIFIAIIVGEVIGIHPIVGAFICGVA 243

Query: 249 VS----MTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTH-AGVFALVYSLIAVV 303
           VS      E    +   +  IGY  FIPIF + +G+ET+IRV+ + + +  L+ +LI+ V
Sbjct: 244 VSEALTKEEHDELLNKNLNAIGYGFFIPIFFLVLGMETNIRVIFNLSNLELLLITLISAV 303

Query: 304 GKIIGCGFGAL-VARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVTMV 362
                 GF AL +  F  I+    G+  +P++  +L+ A++G + G++        V + 
Sbjct: 304 ALKFISGFIALRILGFDRIKNTIGGLLTVPKISASLVAASIGRELGLIGNEIFVTIVALS 363

Query: 363 VITTLITPFLLKWAF 377
           VIT  ITP ++K  F
Sbjct: 364 VITATITPIVVKHIF 378


>pir||C82955 probable sodium/proton antiporter PA5529 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9951867|gb|AAG08914.1|AE004965_6 (AE004965) probable
           sodium/proton antiporter [Pseudomonas aeruginosa]
           Length = 585
           
 Score =  166 bits (417), Expect = 3e-40
 Identities = 102/373 (27%), Positives = 195/373 (51%), Gaps = 3/373 (0%)

Query: 6   ELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSL--LDVVEYGSEVRLLSELGVVM 63
           +LA+I+++A +   L  RL  P  LG ++ G IIGP      ++     ++ L+ELGV+ 
Sbjct: 9   DLAVIMLVAGVVTILFHRLRQPVVLGYIVAGFIIGPHTPPFGLIHDEDTIKTLAELGVIF 68

Query: 64  LLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTAT 123
           L+F  GLE  + +   VG +AFI A + + +   +G+ +     + ++ +LF G +L  +
Sbjct: 69  LMFCLGLEFSLRKLFQVGATAFIAAFLEIVLMIWIGFEIGRFFEWSTMDSLFLGAILAIS 128

Query: 124 SVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIILL 183
           S  +    L D+K    +    I    IV+D+LGI I+ LL  ++  G VE  ++   + 
Sbjct: 129 STTIIVKALGDLKMKNERFAQLIFGVLIVEDILGIGIIALLSGIAVSGSVETGEVFSTVG 188

Query: 184 EVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGITGAY 243
           ++++F I+ +++G  LV  +L    +    E +    + +   F  L  K + + + GA+
Sbjct: 189 KLSLFMIVALVVGILLVPRLLAYVAKFESNEMLLVTVLGLCFGFCLLVVKLEYSMVLGAF 248

Query: 244 LAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLIAVV 303
           L G +++ +    +I ++++     +F  IF V+IG+  D ++L        + ++  V+
Sbjct: 249 LIGAIMAESRQLVQI-ERLIEPVRDMFSAIFFVAIGLLIDPKILVEYAWPIALITVAVVL 307

Query: 304 GKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVTMVV 363
           GK+  CG GA +A      +++VG+G+    E + IIA +G+   + +     V V +  
Sbjct: 308 GKMFSCGMGAFIAGNDGRTSLRVGMGLSQIGEFSFIIAALGMTLKVTSDFLYPVAVAVSA 367

Query: 364 ITTLITPFLLKWA 376
           ITTL+TP+L++ A
Sbjct: 368 ITTLLTPYLIRAA 380


>dbj|BAB11467.1| (AB005233) Na+/H+ antiporter-like protein [Arabidopsis thaliana]
           Length = 810
           
 Score =  145 bits (363), Expect = 6e-34
 Identities = 108/389 (27%), Positives = 198/389 (50%), Gaps = 28/389 (7%)

Query: 5   LELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLL-------DVV---EYGSEVR 54
           L++ I++V+ ++  YL   L  P  + +++GG+++GPSLL       D V   +  + + 
Sbjct: 36  LQIVIVIVLTRVLAYLLRPLRQPRVIAEVIGGIMLGPSLLGRSKAFLDAVFPKKSLTVLE 95

Query: 55  LLSELGVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLG------YLVSVLHGY 108
            L+ LG++  LFLAGLE D +  +  G  A  +A+ G+ +PF LG         ++  G 
Sbjct: 96  TLANLGLLFFLFLAGLEIDTKALRRTGKKALGIALAGITLPFALGIGSSFVLKATISKGV 155

Query: 109 GSLKALFFGGV-LTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAM 167
            S   L F GV L+ T+  +   IL ++K L T++G   ++AA V+DV   ++L L +A+
Sbjct: 156 NSTAFLVFMGVALSITAFPVLARILAELKLLTTEIGRLAMSAAAVNDVAAWILLALAIAL 215

Query: 168 SSRGKVEVEDIEIILLEVAIFFILGILIGHPLVKEVLT--LSERITLPETVTTFAIVIML 225
           S      +  + + L   A  F++G     P +   ++    E   + ET     + ++L
Sbjct: 216 SGSNTSPLVSLWVFLSGCA--FVIGASFIIPPIFRWISRRCHEGEPIEETYICATLAVVL 273

Query: 226 IFAYLAEKFQLAGITGAYLAGLLVSMTEG--SRKITDKIMTIGYSLFIPIFLVSIGIETD 283
           +  ++ +   +  + GA++ G+L+   EG  +  + +K+  +   LF+P++ V+ G++T+
Sbjct: 274 VCGFITDAIGIHSMFGAFVVGVLIP-KEGPFAGALVEKVEDLVSGLFLPLYFVASGLKTN 332

Query: 284 IRVLTHA---GVFALVYSLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALII 340
           +  +  A   G+  LV +  A  GKI+G    +L  +    EAI +G  M  +  V LI+
Sbjct: 333 VATIQGAQSWGLLVLV-TATACFGKILGTLGVSLAFKIPMREAITLGFLMNTKGLVELIV 391

Query: 341 ANVGLKEGILTRGDLAVPVTMVVITTLIT 369
            N+G    +L     A+ V M + TT IT
Sbjct: 392 LNIGKDRKVLNDQTFAIMVLMALFTTFIT 420


>emb|CAB45049.1| (AL078635) putative integral membrane ion antiporter [Amycolatopsis
           orientalis]
           Length = 409
           
 Score =  142 bits (355), Expect = 6e-33
 Identities = 121/394 (30%), Positives = 199/394 (49%), Gaps = 34/394 (8%)

Query: 3   VFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLD----VVEYGSEVR---- 54
           + L+LA+I+V+A++ G ++ RL  P  +G+LL G+++GP+L         + ++VR    
Sbjct: 9   LLLDLAVIVVLARLLGAVARRLDQPPVIGELLAGILLGPTLFGEGFAAALFPTDVRPFLA 68

Query: 55  LLSELGVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLG-----YLV---SVLH 106
            L+ +GV M +F+ GLE +    +  G  A  V+V  + +PF LG     YL     V H
Sbjct: 69  ALANVGVAMFMFMVGLELEQTLLRGRGKLALTVSVSSIVLPFTLGVGLAFYLAMNRPVEH 128

Query: 107 GYGSLKALFFGGVLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVA 166
             G L  LF G  ++ T+  +   IL D   LRT +G   L  A + DVL   +L ++V 
Sbjct: 129 RLGFL--LFIGAAMSVTAFPVLARILQDRGMLRTMLGGLALTCAAIGDVLAWCLLAVVVI 186

Query: 167 MSSRGKVEVEDIEIILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLI 226
           +S  G    E   I+L  + +  +L ++   PL++++ T      LP TV   A    LI
Sbjct: 187 VSG-GASGTEQWLIVLGPIYVALMLWVV--RPLLRKLFTAGVTGALP-TVLAGA----LI 238

Query: 227 FAYLAEKFQLAGITGAYLAGLLVSMTEGS----RKITDKIMTIGYSLFIPIFLVSIGIET 282
              + E   L  I GA+L G++V   EG+     +I D++     +L +P+F +  G++ 
Sbjct: 239 SGAVTELIGLHFIFGAFLFGVIVP-REGTDTLRHRIIDRVEEFNSALLLPVFFIVSGLKV 297

Query: 283 DIRVLTHAGV--FALVYSLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALII 340
           ++  L+  G+  F LV  L+A+ GK  G   GA +      ++  +   M  R    LII
Sbjct: 298 NLSTLSATGLVEFGLVL-LVAIAGKFGGAFVGARLHGLPARKSAALATLMNTRGLTELII 356

Query: 341 ANVGLKEGILTRGDLAVPVTMVVITTLITPFLLK 374
             VGL+ G+L +   ++ V M VITT +   LL+
Sbjct: 357 LTVGLQLGVLDQSLYSIMVAMAVITTAMAGPLLR 390


>gb|AAK41390.1| Na(+)/H(+) antiporter [Sulfolobus solfataricus]
           Length = 391
           
 Score =  141 bits (353), Expect = 1e-32
 Identities = 103/380 (27%), Positives = 195/380 (51%), Gaps = 18/380 (4%)

Query: 6   ELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGP----SLLD------VVEYGSEVRL 55
           +++I +++A+I   L  + G P  +G+LL G+IIGP    SLL+      ++   S +  
Sbjct: 10  DVSIFILLAEILSSLVQKYGLPKLIGELLAGMIIGPYALGSLLNQLLGFPLIGINSYIEF 69

Query: 56  LSELGVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALF 115
           L+E  V++L+F +GLE  +   K  G+  F+ A  G  +PF   Y    +  +G   AL 
Sbjct: 70  LAEFSVILLIFASGLEHGIAPIKSSGILGFLGATFGALLPFFAAYYF-YISSFGLDSALI 128

Query: 116 FGGVLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEV 175
            G  + ATS+    SI+ +  KL+ K    ++++A  DDV+ +++L++++A+       V
Sbjct: 129 LGTAMGATSLAAVASII-EEGKLKGKGINFMVSSAAADDVVDLLLLSVVIAILQGESTSV 187

Query: 176 EDIEIILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQ 235
             I + ++ + + +++ +++   L+ ++   ++RI+  + +  F + ++     L     
Sbjct: 188 TSISLKIIALVVIWVVILVVSIILIPKI---TDRIS-DKYIEEFPLAVLFGLTLLMVSLG 243

Query: 236 LAGITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLT-HAGVFA 294
            + I  A++AG+  + +  + KI +   T+  S+F P+F V IG E +   L  +  + +
Sbjct: 244 YSPIISAFVAGVAFANSVKNSKIKEISSTL-LSVFGPLFFVYIGAEVNFLTLNLNTVILS 302

Query: 295 LVYSLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGD 354
           L  + IA + K +G    AL        A  V +GM+PR E  L+IA++GL    L + +
Sbjct: 303 LELTAIATIFKWLGIFPFALAYLRNAKAANTVALGMVPRGETGLVIASLGLSYNALNQEE 362

Query: 355 LAVPVTMVVITTLITPFLLK 374
               V M + TTLI   L K
Sbjct: 363 FEGIVFMSIFTTLIGSALFK 382


>pir||T05602 hypothetical protein F9D16.170 - Arabidopsis thaliana
           >gi|4454039|emb|CAA23036.1| (AL035394) putative
           Na+/H+-exchanging protein [Arabidopsis thaliana]
           >gi|7269218|emb|CAB79325.1| (AL161559) putative
           Na+/H+-exchanging protein [Arabidopsis thaliana]
           Length = 820
           
 Score =  141 bits (353), Expect = 1e-32
 Identities = 105/400 (26%), Positives = 199/400 (49%), Gaps = 24/400 (6%)

Query: 3   VFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVV----------EYGSE 52
           + L++ I+L++ ++  +L   L  P  + +++GG+++GPS L             +  + 
Sbjct: 33  LILQICIVLLLTRLLAFLLRPLRQPRVIAEIVGGILLGPSALGKSTKFINTVFPPKSLTV 92

Query: 53  VRLLSELGVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLG----YLVSVLHGY 108
           +  L+ LG++  LFL GLE D +  K  G  A  +A+ G+ +PF+LG    + +      
Sbjct: 93  LDTLANLGLIFFLFLVGLELDPKSLKRTGKRALSIALAGITLPFVLGIGTSFALRSSIAD 152

Query: 109 GSLKA---LFFGGVLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLV 165
           G+ KA   +F G  L+ T+  +   IL ++K L T +G   L+AA V+DV   ++L L V
Sbjct: 153 GASKAPFLVFMGVALSITAFPVLARILAEIKLLTTDIGKIALSAAAVNDVAAWILLALAV 212

Query: 166 AMSSRGKVEVEDIEIILLEVAIFFILGILIGHPLVKEVL-TLSERITLPETVTTFAIVIM 224
           A+S  G   +  + + L     F +  I +  P +K +     E   + E      + I+
Sbjct: 213 ALSGEGSSPLTSLWVFLSGCG-FVLFCIFVVQPGIKLIAKRCPEGEPVNELYVCCTLGIV 271

Query: 225 LIFAYLAEKFQLAGITGAYLAGLLVSMTEG--SRKITDKIMTIGYSLFIPIFLVSIGIET 282
           L  +++ +   +  + GA++ G++    EG  +  + +K+  +   LF+P++ VS G++T
Sbjct: 272 LAASFVTDFIGIHALFGAFVIGVIFP-KEGNFANALVEKVEDLVSGLFLPLYFVSSGLKT 330

Query: 283 DIRVLTHAGVFALVYSLI--AVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALII 340
           ++  +  A  + L+  +I  A  GKIIG    +L  +    +++ +G  M  +  V LI+
Sbjct: 331 NVATIQGAQSWGLLVLVIFNACFGKIIGTVLVSLYCKVPLDQSLALGFLMNTKGLVELIV 390

Query: 341 ANVGLKEGILTRGDLAVPVTMVVITTLITPFLLKWAFSKG 380
            N+G   G+L     A+ V M + TT +T  L+   +  G
Sbjct: 391 LNIGKDRGVLNDQIFAIMVLMAIFTTFMTTPLVLAVYKPG 430


>dbj|BAB02053.1| (AB022219) Na+/H+ exchangeing protein-like [Arabidopsis thaliana]
           Length = 800
           
 Score =  140 bits (350), Expect = 2e-32
 Identities = 98/388 (25%), Positives = 187/388 (47%), Gaps = 22/388 (5%)

Query: 3   VFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLL-------DVVEYGSEVRL 55
           + L++ +++V  ++  Y    L  P  + +++GG+++GPS L       D +     + +
Sbjct: 35  IILQIVLVVVFTRLLAYFLKPLKQPRVIAEIIGGILLGPSALGRSKAYLDTIFPKKSLTV 94

Query: 56  LSEL---GVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVS------VLH 106
           L  L   G++  LFL GLE D    K  G  + ++A+ G+ +PF++G   S      +  
Sbjct: 95  LDTLANIGLLFFLFLVGLELDFAAIKKTGKKSLLIAIAGISLPFIVGVGTSFVLSATISK 154

Query: 107 GYGSLKALFFGGV-LTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLV 165
           G   L  + F GV L+ T+  +   IL ++K L T +G   ++AA V+DV   ++L L +
Sbjct: 155 GVDQLPFIVFMGVALSITAFPVLARILAELKLLTTDIGRMAMSAAGVNDVAAWILLALAI 214

Query: 166 AMSSRGKVEVEDIEIILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIML 225
           A+S  G   +  + ++L          + I   L        E   + E      + ++L
Sbjct: 215 ALSGDGTSPLVSVWVLLCGTGFVIFAVVAIKPLLAYMARRCPEGEPVKELYVCVTLTVVL 274

Query: 226 IFAYLAEKFQLAGITGAYLAGLLVSMTEG--SRKITDKIMTIGYSLFIPIFLVSIGIETD 283
             +++ +   +  + GA++ G +V+  EG   R +T+KI  +   L +P++  + G++TD
Sbjct: 275 AASFVTDTIGIHALFGAFVVG-IVAPKEGPFCRILTEKIEDLVSGLLLPLYFAASGLKTD 333

Query: 284 IRVLTHAGVFALVYSLIAVV--GKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIA 341
           +  +  A  + L+  +I     GKI+G    +++ +    EA+ +G  M  +  V LI+ 
Sbjct: 334 VTTIRGAQSWGLLVLVILTTCFGKIVGTVGSSMLCKVPFREAVTLGFLMNTKGLVELIVL 393

Query: 342 NVGLKEGILTRGDLAVPVTMVVITTLIT 369
           N+G    +L     A+ V M + TT IT
Sbjct: 394 NIGKDRKVLNDQAFAILVLMALFTTFIT 421


>gb|AAF26906.1|AF210843_3 (AF210843) unknown [Sorangium cellulosum]
           Length = 713
           
 Score =  134 bits (334), Expect = 2e-30
 Identities = 102/386 (26%), Positives = 180/386 (46%), Gaps = 19/386 (4%)

Query: 7   LAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSE-------- 58
           LA+ILV A+  G L+ RL  P  LG+L GGV++GPS++  +  G    L  E        
Sbjct: 16  LALILVTARASGELARRLRQPEVLGELFGGVVLGPSVVGALAPGFHRALFQEPAVGVVLS 75

Query: 59  ----LGVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSL-KA 113
               +G ++LL +AG+E DV   +       + A+  +  P   G   S L     L   
Sbjct: 76  GISWIGALLLLLMAGIEVDVGILRKEARPGALSALGAIAPPLAAGAAFSALVLDRPLPSG 135

Query: 114 LFFGGVLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKV 173
           LF G VL+ T+V +   +L++ + +R       LAA +V +V   V++ +    SS G  
Sbjct: 136 LFLGIVLSVTAVSVIAKVLIERESMRRSYAQVTLAAGVVSEVAAWVLVAM--TSSSYGAS 193

Query: 174 EVEDIEIILLEVAIFFILGILIGHPLVKEVLT-LSERITLPETVTTFAIVIMLIFAYLAE 232
               +    L  + F +  +L+G  L    +  +++   + +   +  +V+  + A L +
Sbjct: 194 PALAVARSALLASGFLLFMVLVGRRLTHLAMRWVADATRVSKGQVSLVLVLTFLAAALTQ 253

Query: 233 KFQLAGITGAYLAGLLV-SMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAG 291
           +  L  + GA+  G+L+ S    +R + D + T+   LF P+F V  G+  D+  L    
Sbjct: 254 RLGLHPLLGAFALGVLLNSAPRTNRPLLDGVQTLVAGLFAPVFFVLAGMRVDVSQLRTPA 313

Query: 292 VFALVYSLI--AVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGI 349
            +  V  L+  A   K++    GA +   +  EA  V +G+  +    LI+A VG++ G+
Sbjct: 314 AWGTVALLLATATAAKVVPAALGARLGGLRGSEAALVAVGLNMKGGTDLIVAIVGVELGL 373

Query: 350 LTRGDLAVPVTMVVITTLITPFLLKW 375
           L+     +   + ++T   +P LL W
Sbjct: 374 LSNEAYTMYAVVALVTVTASPALLIW 399


>pir||S74951 Na+/H+-exchanging protein slr1595 - Synechocystis sp.  (strain PCC
           6803) >gi|1652066|dbj|BAA16991.1| (D90902) Na/H
           antiporter [Synechocystis sp.]
           Length = 410
           
 Score =  134 bits (333), Expect = 2e-30
 Identities = 103/397 (25%), Positives = 191/397 (47%), Gaps = 27/397 (6%)

Query: 3   VFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSE---------- 52
           +   + +I+ +A++ G L  R   P  +G+++ G+++GPSLL ++    E          
Sbjct: 9   ILANIIVIIGLARLIGLLFARFQQPPVIGEIIAGIMLGPSLLGLLSPALEKSFFPATTQP 68

Query: 53  -VRLLSELGVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSL 111
            + LLSE+G++  +FL GLE + +  +     A + + + +F PF+LG ++S    Y   
Sbjct: 69  FLYLLSEIGLIFYMFLVGLELNPQYLRQKLKVAILTSNVSIFFPFVLGIVLSFFVLYSLN 128

Query: 112 K---------ALFFGGVLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILT 162
           +         ALF G  ++ T+  +   IL D    +T +GT  L  A VDD+    +L 
Sbjct: 129 QPNKTSFIPFALFIGAAMSITAFPVLARILKDTGLDKTPLGTLGLTCASVDDISAWCLLA 188

Query: 163 LLVAMSSRGKVEVEDIEIILLEVAIFFILGILIGHPLVKEVL-TLSERITLPETVTTFAI 221
           + +A++      +      LL + ++ +  + +G    K +L    ++  L + + TF  
Sbjct: 189 IAIAVTRTD--NIFGAFPTLLGIIVYTVFMVTLGRKFFKYILRNYGQKNYLSQGLLTFIY 246

Query: 222 VIMLIFAYLAEKFQLAGITGAYLAG-LLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGI 280
           +++++ A L E   +  I G ++ G +L   T  S ++  K      +  +PIF    G+
Sbjct: 247 IMVILSAMLTEWIGIDVIFGGFILGAILPKNTNLSTELATKTEDFVSTFLLPIFFAYSGL 306

Query: 281 ETDIRVLTHAGVFALVYSLI--AVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVAL 338
            TD+ +L    ++A+   ++  A+ GK  G          +  EA  +G  M  R    L
Sbjct: 307 STDLGLLNKPYLWAVCALVVAAAIAGKYCGVYVTTRALGVEKQEAKALGWLMNTRGLTEL 366

Query: 339 IIANVGLKEGILTRGDLAVPVTMVVITTLIT-PFLLK 374
           II NVGLK G+++     + V M +ITT+IT P ++K
Sbjct: 367 IILNVGLKLGVISPVIFTMFVIMAIITTIITSPLVVK 403


>pir||T45912 hypothetical protein F5K20.20 - Arabidopsis thaliana
           >gi|7629992|emb|CAB88334.1| (AL132960) putative protein
           [Arabidopsis thaliana]
           Length = 842
           
 Score =  132 bits (330), Expect = 5e-30
 Identities = 102/400 (25%), Positives = 192/400 (47%), Gaps = 35/400 (8%)

Query: 3   VFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDV-VEYGSEV-------- 53
           + ++ A+I+ +++    L   L  P  + +++GG+++GPS L   + Y   +        
Sbjct: 29  LIVQTALIIAVSRFLAVLFKPLRQPKVIAEIVGGILLGPSALGRNMAYMDRIFPKWSMPI 88

Query: 54  -RLLSELGVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLG-----------YL 101
              ++ +G++  LFL GLE D+   +  G  AF +AV G+ +PF+ G           Y 
Sbjct: 89  LESVASIGLLFFLFLVGLELDLSSIRRSGKRAFGIAVAGITLPFIAGVGVAFVIRNTLYT 148

Query: 102 VSVLHGYGSLKALFFGGVLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVIL 161
            +   GY     +F G  L+ T+  +   IL ++K L T++G T +AAA  +DV   ++L
Sbjct: 149 AADKPGYAEF-LVFMGVALSITAFPVLARILAELKLLTTQIGETAMAAAAFNDVAAWILL 207

Query: 162 TLLVAMSSRG------KVEVEDIEIILLEVAIFFILGILIGHPLVKEVLTLS--ERITLP 213
            L VA++  G      K        +LL  A F +  +++  P +K V      E   + 
Sbjct: 208 ALAVALAGNGGEGGGEKKSPLVSLWVLLSGAGFVVFMLVVIRPGMKWVAKRGSPENDVVR 267

Query: 214 ETVTTFAIVIMLIFAYLAEKFQLAGITGAYLAGLLVSMT-EGSRKITDKIMTIGYSLFIP 272
           E+     +  +++  +  +   +  I GA++ GL +    E  +++ ++I      L +P
Sbjct: 268 ESYVCLTLAGVMVSGFATDLIGIHSIFGAFVFGLTIPKDGEFGQRLIERIEDFVSGLLLP 327

Query: 273 IFLVSIGIETDIRVLTHA---GVFALVYSLIAVVGKIIGCGFGALVARFKPIEAIQVGIG 329
           ++  + G++TD+  +  A   G+  LV  + A  GKI+G    A++ +    EA+ +G  
Sbjct: 328 LYFATSGLKTDVAKIRGAESWGMLGLVV-VTACAGKIVGTFVVAVMVKVPAREALTLGFL 386

Query: 330 MIPRMEVALIIANVGLKEGILTRGDLAVPVTMVVITTLIT 369
           M  +  V LI+ N+G ++ +L     A+ V M + TT IT
Sbjct: 387 MNTKGLVELIVLNIGKEKKVLNDETFAILVLMALFTTFIT 426


>gi|6322367 Yjl094cp [Saccharomyces cerevisiae] >gi|731972|sp|P40309|YJJ4_YEAST
           HYPOTHETICAL 97.1 KD PROTEIN IN BCK1-TOK1 INTERGENIC
           REGION >gi|630170|pir||S46584 probable membrane protein
           YJL094c - yeast (Saccharomyces cerevisiae)
           >gi|521094|emb|CAA54359.1| (X77087) 12 transmembrane
           domains; J0909 ORF [Saccharomyces cerevisiae]
           >gi|1008268|emb|CAA89387.1| (Z49369) ORF YJL094c
           [Saccharomyces cerevisiae]
           Length = 873
           
 Score =  131 bits (326), Expect = 1e-29
 Identities = 100/396 (25%), Positives = 197/396 (49%), Gaps = 36/396 (9%)

Query: 6   ELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLL-DVVEYGSEV---------RL 55
           +  +IL++  +       +  P  + +++ GVI+GP++   +  Y + +          L
Sbjct: 29  QACLILLVCNLIHIPFSMMRQPKVISEVISGVILGPTIFGQIPNYTNTIFPTSSIPGLNL 88

Query: 56  LSELGVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSV--LHGYG---- 109
           ++ LG+++ +F  GLE D+   K     A ++ ++ + VPF  G L+++   H Y     
Sbjct: 89  VANLGIILFMFFLGLEVDIAFIKKHLKKALVIGIVTLAVPFGFGCLLAIPLFHTYANKTE 148

Query: 110 -------SLKALFFGGVLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILT 162
                  S+  +F    ++ T+  +   IL +++ ++ + G  +LAA I++D++G ++L 
Sbjct: 149 GERHIKFSVFMVFIAVSISVTAFPVLCRILNELRLIKDRAGIVVLAAGIINDIMGWILLA 208

Query: 163 LLVAMSSRGKVEVEDIEIILLEVAIFFILGILIGHPLVKEVLTLSERI--TLPETVTTFA 220
           L + +SS     V  + I+L+  A F I    + + L++ VL  +  +  + P  + T  
Sbjct: 209 LSIILSSAEGSPVNTVYILLITFAWFLIYFFPLKY-LLRWVLIRTHELDRSKPSPLATMC 267

Query: 221 IV-IMLIFAYLAEKFQLAGITGAYLAGLLVSMTEG-SRKITDKIMTIGYSLFIPIFLVSI 278
           I+ IM I AY  +   +  I GA++AGL+V   +    K+T+++  I   +FIPI+    
Sbjct: 268 ILFIMFISAYFTDIIGVHPIFGAFIAGLVVPRDDHYVVKLTERMEDIPNIVFIPIYFAVA 327

Query: 279 GIETDIRVLTHAGVFALVYSL--IAVVGKIIGCGFGALVARFKPI---EAIQVGIGMIPR 333
           G+  D+ +L     +  V++   IA+  KII    G L A+   +   EA   G+ M  +
Sbjct: 328 GLNVDLTLLNEGRDWGYVFATIGIAIFTKIIS---GTLTAKLTGLFWREATAAGVLMSCK 384

Query: 334 MEVALIIANVGLKEGILTRGDLAVPVTMVVITTLIT 369
             V +++  VGL  GI++R    + V M +++T +T
Sbjct: 385 GIVEIVVLTVGLNAGIISRKIFGMFVLMALVSTFVT 420


>gb|AAF24561.1|AC007764_3 (AC007764) F22C12.7 [Arabidopsis thaliana]
           Length = 868
           
 Score =  131 bits (325), Expect = 2e-29
 Identities = 97/359 (27%), Positives = 173/359 (48%), Gaps = 27/359 (7%)

Query: 35  GGVIIGPSLLD-VVEYGSEV---------RLLSELGVVMLLFLAGLETDVEEFKHVGLSA 84
           GG+++GPS L  +  Y + +           L+ LG+++ LFL GLE D+   +  G  A
Sbjct: 131 GGILLGPSALGRITSYKNSIFPARSLTVLDTLANLGLLLFLFLVGLEIDLTSLRRTGKKA 190

Query: 85  FIVAVMGVFVPFLLGYLVSVLHGYGSLKA---------LFFGGVLTATSVGLTTSILMDM 135
             +A  G+ +PF +G + S      S            +F G  L+ T+ G+   IL ++
Sbjct: 191 ISIAAAGMLLPFGMGIVTSFAFPEASSSGDNSKVLPFIIFMGVALSITAFGVLARILAEL 250

Query: 136 KKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIILLEVAIFFILGILI 195
           K L T +G   + AA ++DV   V+L L V++S      +  + ++L  +A  F++   +
Sbjct: 251 KLLTTDLGRISMNAAAINDVAAWVLLALAVSLSGDRNSPLVPLWVLLSGIA--FVIACFL 308

Query: 196 GHPLVKEVLT--LSERITLPETVTTFAIVIMLIFAYLAEKFQLAGITGAYLAGLLVSMTE 253
             P + + ++    E   + E     A+  +L+  +  +   +  I GA++ G+L     
Sbjct: 309 IVPRIFKFISRRCPEGEPIGEMYVCVALCAVLLAGFATDAIGIHAIFGAFVMGVLFPKGH 368

Query: 254 GSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHA---GVFALVYSLIAVVGKIIGCG 310
            S  I +KI  +   L +P++ V  G++TDI  +      G  ALV  + A  GKI+G  
Sbjct: 369 FSDAIVEKIEDLVMGLLLPLYFVMSGLKTDITTIQGVKSWGRLALVI-VTACFGKIVGTV 427

Query: 311 FGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVTMVVITTLIT 369
             AL+ + +  E++ +G+ M  +  V LI+ N+G    +L+    A+ V M + TT IT
Sbjct: 428 SVALLCKVRLRESVVLGVLMNTKGLVELIVLNIGKDRKVLSDQTFAIMVLMAIFTTFIT 486


>pir||S76532 hypothetical protein - Synechocystis sp. (strain PCC 6803)
           >gi|1001647|dbj|BAA10378.1| (D64002) Na(+)/H(+)
           antiporter [Synechocystis sp.]
           Length = 698
           
 Score =  127 bits (315), Expect = 3e-28
 Identities = 102/384 (26%), Positives = 191/384 (49%), Gaps = 25/384 (6%)

Query: 5   LELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSE-VRLLSELGVVM 63
           ++  I+L++  I   +  RL  P  +G L  G+++G S L V+   SE ++L +++G + 
Sbjct: 14  IDFTILLLVTLILPPIFERLKLPGLVGLLFAGIVLGKSGLGVLNEDSESIKLFTDIGKIY 73

Query: 64  LLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTAT 123
           L+F+AGLE D+ +F+     + +   +   VP L G  V +  GY S  A    G L A+
Sbjct: 74  LMFVAGLEIDMVDFRRTRNRSLLYGSLTFAVPLLTGLAVGLTFGY-SFNASVLLGSLFAS 132

Query: 124 SVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIILL 183
              L   I+  +  +R +     + A I  D+  +++L + +++ S G      + + L+
Sbjct: 133 HTLLGYPIVQRLGIVRNQAVMVTIGATIFTDIAALLVLAICISIHS-GSFSPAGLVVQLV 191

Query: 184 EVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIF--AYLAEKFQLAGITG 241
            +A++  L +LIG            R T  E    F  V++ +F  +  +E   +  I G
Sbjct: 192 AIAVYSAL-VLIGFDWAGREYF---RRTGDEQSNQFLFVLLAVFLASVGSELINVDKIVG 247

Query: 242 AYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIR--VLTHAGVFALVYSL 299
           A+LAGL V+   G+  + +K+  +G +LFIP F + IG+  D+   ++T   +F LV ++
Sbjct: 248 AFLAGLAVNDVLGNSPVKEKVEFLGTTLFIPFFFIGIGLLLDLPAFLVTLTTLFPLVVAI 307

Query: 300 IAVVGKIIGCGFGALVARFKP----IEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDL 355
             VVG I+  G  A++A++K     +E + +    IP++   L  A  G  + +   GD 
Sbjct: 308 --VVGLILSKGVAAILAQWKLGYTWVEGLTMWSLSIPQVAATLAAAVAGY-QAVNAAGDR 364

Query: 356 AVP-------VTMVVITTLITPFL 372
            V        + +++IT+++ P +
Sbjct: 365 LVSETVLNTIIVLMLITSIVGPLM 388


>gb|AAD22684.1|AC007063_10 (AC007063) putative Na+/H+ antiporter [Arabidopsis thaliana]
           Length = 821
           
 Score =  125 bits (312), Expect = 6e-28
 Identities = 93/392 (23%), Positives = 193/392 (48%), Gaps = 29/392 (7%)

Query: 5   LELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLD--------VVEYGSEVRL- 55
           L+L +++V+ + F ++      P  + ++LGG+++GPS+L         +    S + L 
Sbjct: 42  LQLTLVVVVTRFFVFILKPFRQPRVISEILGGIVLGPSVLGRSTKFAHTIFPQRSVMVLE 101

Query: 56  -LSELGVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSV-LH------G 107
            ++ +G++  LFL G+E D+   +  G  A  +A+ G+ +PFL+G   S  +H      G
Sbjct: 102 TMANVGLLYFLFLVGVEMDIMVVRKTGKRALTIAIGGMVLPFLIGAAFSFSMHRSEDHLG 161

Query: 108 YGSLKALFFGGVLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAM 167
            G+   LF G  L+ T+  +   IL ++K + T++G   ++AA+V+D+   ++L L +A+
Sbjct: 162 QGTY-ILFLGVALSVTAFPVLARILAELKLINTEIGRISMSAALVNDMFAWILLALAIAL 220

Query: 168 SSRGKVEVEDIEIILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIML-- 225
           +   K     +  +++  A+F  + + +  P +  ++    +    E  + F I ++L  
Sbjct: 221 AESDKTSFASL-WVMISSAVFIAVCVFVVRPGIAWII---RKTPEGENFSEFHICLILTG 276

Query: 226 --IFAYLAEKFQLAGITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETD 283
             I  ++ +      + GA++ GL++        + +K+      L +P+F    G++T+
Sbjct: 277 VMISGFITDAIGTHSVFGAFVFGLVIPNGPLGLTLIEKLEDFVSGLLLPLFFAISGLKTN 336

Query: 284 IRVLTHAGVFALVYSLI--AVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIA 341
           I  +     +  ++ +I  A  GK+IG    A        E I +G+ +  +  V +I+ 
Sbjct: 337 IAAIQGPATWLTLFLVIFLACAGKVIGTVIVAFFHGMPVREGITLGLLLNTKGLVEMIVL 396

Query: 342 NVGLKEGILTRGDLAVPVTM-VVITTLITPFL 372
           NVG  + +L     A  V + +V+T +ITP +
Sbjct: 397 NVGKDQKVLDDETFATMVLVALVMTGVITPIV 428


>dbj|BAB06563.1| (AP001516) Na+/H+ antiporter [Bacillus halodurans]
           Length = 686
           
 Score =  125 bits (311), Expect = 8e-28
 Identities = 96/377 (25%), Positives = 190/377 (49%), Gaps = 14/377 (3%)

Query: 5   LELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVML 64
           L  AI +V+  +   L  RL  P  +G +L GV+IGP+   +++    + LL  +G++ +
Sbjct: 11  LIFAIAMVVFFVAPLLMSRLRIPGIIGLILAGVVIGPNGFALLDRDPTIVLLGTVGLLYI 70

Query: 65  LFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTATS 124
           +F+AGLE D+E FK     + +   +   +PFL G + + + G+ +  A+    +L + +
Sbjct: 71  IFIAGLEIDLEGFKKYRNRSVLFGTLSFTIPFLFGLVFTFILGFSTPAAILLASILGSHT 130

Query: 125 VGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIILLE 184
           + L   I   +   + +  TT +   I+ D L +++L  +VA S +G++       I + 
Sbjct: 131 L-LAYPIASRLGISKDRGVTTAVGGTIMTDTLALLVLA-IVAGSMQGELNSTFWFTIAVS 188

Query: 185 VAIFFILGILIGHPLVKEVL-TLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGITGAY 243
           + ++  + +++   L K    T+S    L      F + I+ + AY A    L  I GA+
Sbjct: 189 LVLYVAITLILIPILAKSFFRTMSSEGALE---FIFVMSILFVTAYGATLAGLEPIIGAF 245

Query: 244 LAGLLVS--MTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVL---THAGVFALVYS 298
           LAGL ++  + E S  + ++I  +G +LFIP FL+S+G+  DIRVL     A + A +  
Sbjct: 246 LAGLALNRFILEHS-PLMNRIKFVGNALFIPFFLLSVGMLMDIRVLLGDPSAWLLAALVV 304

Query: 299 LIAVVGKIIGCGFGALVARFKPIEAIQVGIGM-IPRMEVALIIANVGLKEGILTRGDLAV 357
           +   +GK +       +  +  ++ I++  G+ +P+    L    VG   G+     +  
Sbjct: 305 IFVQLGKFLAAFISGKLYNYS-MDQIKLMFGLSVPQAAATLAATLVGFDLGLFDSAVVNA 363

Query: 358 PVTMVVITTLITPFLLK 374
            + M+++T ++ P++++
Sbjct: 364 VIVMILVTCMVGPYVVE 380


>pir||T50062 Probable K+/H+-antiporter [imported] - fission yeast
           (Schizosaccharomyces pombe) >gi|7160220|emb|CAB76234.1|
           (AL157994) Probable K+/H+-antiporter
           [Schizosaccharomyces pombe]
           Length = 898
           
 Score =  121 bits (301), Expect = 1e-26
 Identities = 103/393 (26%), Positives = 191/393 (48%), Gaps = 24/393 (6%)

Query: 5   LELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSL-------LDVVEYGSEV---R 54
           ++  II+ + ++       L  P  + +++GG+++GP++       LD +   S +    
Sbjct: 35  VQAIIIIALCRLIHIPLSFLQQPRVIAEIIGGIVLGPTVMGRIPKFLDYIFPTSSMGPLN 94

Query: 55  LLSELGVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSV-LHGYGSLK- 112
           L+S LG+V+ LF+ G+E D+           +V V  + +PF  G  +S  L+ + + + 
Sbjct: 95  LVSNLGLVLFLFVIGMEVDLRVLVLNYKVTLLVTVFSIVIPFGAGAGISAGLYKFTTREF 154

Query: 113 -----ALFFGGVLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAM 167
                 LF    ++ T+  +   IL ++  L  +VG  +L+A I +DV+G ++L L V +
Sbjct: 155 EFGKFLLFISTAMSITAFPVLARILSELHLLHKRVGVIVLSAGIGNDVIGWILLALSVTL 214

Query: 168 SSRGKVEVEDIEIILLEVAIFFILGILIGHPLV--KEVLTLSERITLPETVTTFAIVIML 225
            + G   V  + I+LL +     L I I  PLV    V T S +    E+     + ++L
Sbjct: 215 VNSGS-GVRAVYILLLALGWCLFLFIAI-KPLVYLLAVKTRSLKDKPSESFICIVLSMVL 272

Query: 226 IFAYLAEKFQLAGITGAYLAGLLV-SMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDI 284
           + A+  +   +  I G +L G ++    + + KIT+KI  +   LF+P++  S G++T+I
Sbjct: 273 VSAFFTDIIGIHPIFGGFLVGTIIPHENDLTVKITEKIEDLVNCLFLPLYFASSGLKTNI 332

Query: 285 RVLTHAGVFALVYSLI--AVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIAN 342
             L    ++      I  A+  K+      A + +    +++ VG  M  +  V LI+ N
Sbjct: 333 STLNTGKIWGYTIGTICVAIASKMGSSMLAARILKMPWSDSLVVGSLMSCKGLVELIVLN 392

Query: 343 VGLKEGILTRGDLAVPVTMVVITTLITPFLLKW 375
           +GL  GIL     ++ V M VITT +T  + K+
Sbjct: 393 IGLSTGILNETIFSMFVFMAVITTFVTTPMTKF 425


>gi|11497833 Na+/H+ antiporter (napA-1) [Archaeoglobus fulgidus]
           >gi|7451786|pir||A69277 Na+/H+ antiporter (napA-1)
           homolog - Archaeoglobus fulgidus
           >gi|2650426|gb|AAB91016.1| (AE001091) Na+/H+ antiporter
           (napA-1) [Archaeoglobus fulgidus]
           Length = 377
           
 Score =  120 bits (299), Expect = 2e-26
 Identities = 98/382 (25%), Positives = 185/382 (47%), Gaps = 17/382 (4%)

Query: 1   MEVFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELG 60
           +E F  +A+I + A I   ++ +L  P  + +++ G+I G S L+V+     +  LS  G
Sbjct: 4   VEQFATIALISLTAFISPLIADKLRVPVVVLEIVLGMIFGVSFLNVIYASEWLSFLSLFG 63

Query: 61  VVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVL 120
           ++ L+FLAGLE D +     G    +VA     +   L   ++ L G      LF+  +L
Sbjct: 64  LIFLMFLAGLEIDADVVLKSGHLKRVVAFFA--LSLALSVALTALMGLN----LFYAIIL 117

Query: 121 TATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEI 180
           T  +VG+  S+L ++   +   G   +  A+V D   + +L++       G ++V    +
Sbjct: 118 TNVAVGVVVSVLREIGLEKEDFGQLNIVTALVSDFSTMFLLSIYFI---TGYLQVAFAFL 174

Query: 181 ILLEVAIFFILG-ILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGI 239
           I+L     +  G ++I H    + ++        E     ++ IM++F  L+    +  I
Sbjct: 175 IILVFLAAYRFGKLVIWH--FPDFISRWFSDEPSEIGVRGSLAIMILFVGLSSLLGVEAI 232

Query: 240 TGAYLAGLLVSMT-EGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGV-FALVY 297
            GA+LAG+L+S+T  G +K+ DK+  +G+  FIPIF +  G E +I   T AG     + 
Sbjct: 233 LGAFLAGVLLSITFRGGKKLYDKLYGMGFGFFIPIFFIKTGSELNI---TQAGEGIGFIL 289

Query: 298 SLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAV 357
            L+AV   + G       + F    AI +G+    ++ + +    +G+  G++T  +   
Sbjct: 290 LLLAVSVAVKGIPSLIFASNFGLRRAISMGMLQSTKLSLTIAGVAIGVSSGVITEFESTA 349

Query: 358 PVTMVVITTLITPFLLKWAFSK 379
            VT  +I+ L++P L ++ + +
Sbjct: 350 LVTFTIISCLLSPTLFRFLYPR 371


>gb|AAF69026.1| (AF182516) unknown [Pseudomonas putida]
           Length = 390
           
 Score =  114 bits (282), Expect = 2e-24
 Identities = 99/374 (26%), Positives = 178/374 (47%), Gaps = 12/374 (3%)

Query: 3   VFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVV 62
           VFL LA++L++      L+ RL   A  G LL G++IGPS+  ++     V  LSE+GVV
Sbjct: 5   VFL-LAVVLLVP-----LAQRLKMGAVPGYLLAGILIGPSVFGLLGNPDNVARLSEMGVV 58

Query: 63  MLLFLAGLETDVEEFKHVGLSAFIVAVMGV-FVPFLLGYLVSVLHGYGSLKALFFGGVLT 121
           MLLF+ GLE   +    +  + F V  + V     LLG L   L       A+  G  L 
Sbjct: 59  MLLFVIGLELSPKRLWTMRRALFGVGSLQVGLTAVLLGLLAFWLFDQSKPAAIVLGLGLA 118

Query: 122 ATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEI- 180
            +S      +L + K L    G   +A  +  D+  I ++ ++  +   G V   D    
Sbjct: 119 LSSTAFGLQVLAERKDLGKPHGRMAVAILLFQDIAAIPLIAVVPLLG--GDVSTADEGAW 176

Query: 181 ILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGIT 240
            LL V +   + I+ G  L+  +   +    LPE  T  A++++L  A+L E   ++   
Sbjct: 177 PLLAVVVGIGVLIVFGRYLLTPIFKWTVGSGLPELSTATALLVVLGTAWLMEHVGVSMAL 236

Query: 241 GAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLI 300
           GA+LAG+L++ +    ++  +I  I   LF+ +F V +G+  D+R+L    +  L  +L+
Sbjct: 237 GAFLAGVLMAESPFRHELETQIEPI-KGLFLGLFFVGVGMSADLRLLFGMPLMVLGLTLL 295

Query: 301 AVVGKI-IGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPV 359
            V  K+ +  G G  +      +A+ +G+ +    E   ++  + L+  +LT+    + V
Sbjct: 296 LVAIKLPLLYGLGRTMGGLNKSQALCLGVVLASGGEFXFVVFKLALEHQVLTQAVHDLLV 355

Query: 360 TMVVITTLITPFLL 373
             + ++  + P ++
Sbjct: 356 LAITLSMAVVPLVM 369


>pir||C83496 glutathione-regulated potassium-efflux system protein KefB PA1207
           [imported] - Pseudomonas aeruginosa (strain PAO1)
           >gi|9947134|gb|AAG04596.1|AE004550_12 (AE004550)
           glutathione-regulated potassium-efflux system protein
           KefB [Pseudomonas aeruginosa]
           Length = 613
           
 Score =  112 bits (278), Expect = 6e-24
 Identities = 97/381 (25%), Positives = 186/381 (48%), Gaps = 20/381 (5%)

Query: 4   FLELAIILVIAKIFGY-LSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVV 62
           FL+  ++ +IA +F   L+ RL   A LG LL GV+IGPS+L +V+    V  +SE+GVV
Sbjct: 7   FLQSGVVFLIAAVFMVPLAKRLQLGAVLGYLLAGVLIGPSVLGLVDNPESVAQISEMGVV 66

Query: 63  MLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVL---HGYGSLKALFFGGV 119
           +LLF+ GLE        +  S F V ++ V +  L+   V+++       S   L  G  
Sbjct: 67  LLLFIIGLELSPRRLWVMRKSVFGVGLLQVLLTGLVIGTVALVGFDQPVNSAVVLGLGLA 126

Query: 120 LTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMS-----SRGKVE 174
           L++T+ GL   IL + K+L    G    A  +  D+  I ++ ++  +S     + G   
Sbjct: 127 LSSTAFGL--QILAERKELTQPHGRLAFAILLFQDIAAIPLIAMIPLLSGAHSDAGGSEL 184

Query: 175 VEDIEIILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKF 234
            + ++++    A+     ++ G  L++ V  +  +  L +  T  A+++++  A L E  
Sbjct: 185 TQTLKVVGSIAAV-----VVGGRYLLRPVFRIVAQTKLQDMSTATALLVVMGTALLMELA 239

Query: 235 QLAGITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAG--V 292
            ++   GA+LAGLL++ +E   ++  +I      L + +F +S+G+  DI +L  +   V
Sbjct: 240 GVSMALGAFLAGLLLADSEYRHELEAQIEPF-KGLLLGLFFISVGMSADISLLLKSPWMV 298

Query: 293 FALVYSLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTR 352
             L   LIA+   ++    G +        A+++G+ +    E A ++  +   +G+   
Sbjct: 299 LGLTVLLIALKAPVL-YFVGRISGGLDKASALRLGVVLAAGGEFAFVVFKMARDQGLFQN 357

Query: 353 GDLAVPVTMVVITTLITPFLL 373
               + V  + ++  +TP L+
Sbjct: 358 DLHNLLVLSITLSMALTPLLV 378


>pir||A69845 Na+/H+ antiporter homolog yjbQ - Bacillus subtilis
           >gi|2633518|emb|CAB13021.1| (Z99110) similar to Na+/H+
           antiporter [Bacillus subtilis]
           Length = 614
           
 Score =  111 bits (274), Expect = 2e-23
 Identities = 91/392 (23%), Positives = 183/392 (46%), Gaps = 25/392 (6%)

Query: 7   LAIILVIAKIFGYLSVR--LGFPAALGQLLGGVIIGPSLLD-VVEYGSEVRLLSELGVVM 63
           L ++L++A +   L  R  L  P  + +++ G+IIG S L+ VVE  + ++ LS LG + 
Sbjct: 9   LVVVLIVAFLTPILLHRFKLSIPVVVAEIIMGLIIGKSGLNLVVEGDTWLQTLSMLGFIF 68

Query: 64  LLFLAGLETDVEEFKHVGLSAFIV-------AVMGVFVPFLLGYLVSVLHGYGSLKALFF 116
           L+FL+GLE D   F+      F+              V F+  +++S+L  YG + A F 
Sbjct: 69  LMFLSGLEIDFSSFEKGKKKQFLPNGKEAPNTFAAASVIFVGIFILSLLLSYGFVLAGFI 128

Query: 117 GG------VLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSR 170
                   +++  S+G+    L + + + + +G  IL  A++ D+  +++L +  ++   
Sbjct: 129 QNAFLMTLIISTISLGVVVPTLKEERIMNSNIGQIILLVAVIADLATMILLAVFSSLYGE 188

Query: 171 GKVEVEDIEIILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYL 230
               +  + I+     + +  G +  H     V ++S+      T   F ++I+L+   L
Sbjct: 189 DSGNMWLLMILFAAGVVLYFFGRVFKHRSF--VQSMSKGTIQIGTRAIFTLIIVLVA--L 244

Query: 231 AEKFQLAGITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHA 290
           +E      I GA+LAG+LVS+   ++++  ++ + GY   IPIF V +G++ DI  L   
Sbjct: 245 SESLGAENILGAFLAGVLVSLLSPNKELVQQLDSFGYGFLIPIFFVMVGVKLDIWTLFQD 304

Query: 291 GVFALVYSLI---AVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKE 347
               ++  L+    +V KII   +  L   +        G  +   + + +  A +G + 
Sbjct: 305 KTILIMIPLLLLALLVSKIIPVMY--LKKWYDNRTIFASGFLLTSTLSLVIAAATIGQQL 362

Query: 348 GILTRGDLAVPVTMVVITTLITPFLLKWAFSK 379
            +++       + + VI ++ TP   K  + +
Sbjct: 363 HVISTNMSGALILVAVIASIFTPICFKKLYKR 394


>pir||D71642 glutathione-regulated potassium-efflux system protein kefb  (kefB)
           RP810 - Rickettsia prowazekii
           >gi|3861337|emb|CAA15236.1| (AJ235273)
           GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYSTEM PROTEIN
           KEFB (kefB) [Rickettsia prowazekii]
           Length = 575
           
 Score =  111 bits (274), Expect = 2e-23
 Identities = 92/373 (24%), Positives = 166/373 (43%), Gaps = 5/373 (1%)

Query: 3   VFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVV 62
           + + + I+L  A     +  R      LG L+ G  IG   L +V Y  + +LL ELGVV
Sbjct: 5   ILINVIILLGTAVFIVAILKRFRLSPVLGYLIAGAAIGDHGLKIVTY-DQTKLLGELGVV 63

Query: 63  MLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTA 122
            LLF  GLE   E  K +    F +  + V    ++     VL    S  A+  GG L  
Sbjct: 64  FLLFAIGLELSFERLKAMRRYVFGLGSLQVLTTAIVIAGAMVLIDGNSSAAIITGGGLAL 123

Query: 123 TSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVE-DIEII 181
           +S  L   ++ + +   T++G   LA  ++ D+  + +L ++  ++S  K  +   + I 
Sbjct: 124 SSTALVMQVIDENRSQSTQIGRISLAILLLQDLAVVPLLVIVPLLASNNKASLAVALGIA 183

Query: 182 LLEVAIFFILGILIGHPLVKEVLTL--SERITLPETVTTFAIVIMLIFAYLAEKFQLAGI 239
            L+     +   ++G  L++ V +   SE     E   +  ++I+L  A+  E F L+  
Sbjct: 184 FLKAVTALLTIFIVGRVLLRPVFSFISSESNNTSELPISMTLLIVLSAAWATETFGLSLA 243

Query: 240 TGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSL 299
            GA++AG+LV+ TE   +  + I     SLF+ +F +++G+  D   +       L  S+
Sbjct: 244 LGAFVAGVLVAETEFRLQAEESIYPF-KSLFLGLFFMTVGMNIDALEMYEKISHILTLSI 302

Query: 300 IAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPV 359
             +  K +      ++  F    A   G+ +    E   I+ ++G   G+L      + +
Sbjct: 303 ALICIKTLIITAFCILFGFNKGVAFYSGLLLSQGGEFGFILFSLGKDSGVLEESTADILL 362

Query: 360 TMVVITTLITPFL 372
            +V  T  +TP L
Sbjct: 363 LVVTFTMALTPLL 375


>sp|P39830|YBAL_ECOLI HYPOTHETICAL 59.4 KD PROTEIN IN GSK-FSR INTERGENIC REGION
           >gi|7444646|pir||E64778 probable membrane protein ybaL -
           Escherichia coli >gi|1773160|gb|AAB40232.1| (U82664)
           similar to Y. enterocolitica RosB [Escherichia coli]
           >gi|1786685|gb|AAC73580.1| (AE000154) putative transport
           protein [Escherichia coli K12]
           Length = 558
           
 Score =  106 bits (263), Expect = 3e-22
 Identities = 92/370 (24%), Positives = 169/370 (44%), Gaps = 9/370 (2%)

Query: 11  LVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVMLLFLAGL 70
           LV+A I G L+ +L     +G LL GV+ GP     V        L+ELGV++L+F  GL
Sbjct: 15  LVLAFILGMLANKLRISPLVGYLLAGVLAGPFTPGFVADTKLAPELAELGVILLMFGVGL 74

Query: 71  ETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTATSVGLTTS 130
              +++   V   A   A+  + V  LLG  +S + G+  +  + FG  L+  S  +   
Sbjct: 75  HFSLKDLMAVKAIAIPGAIAQIAVATLLGMALSAVLGWSLMTGIVFGLCLSTASTVVLLR 134

Query: 131 ILMDMKKLRTKVGTTILAAAIVDD---VLGIVILTLLVAMSSRGKVE----VEDIEIILL 183
            L + + + ++ G   +   IV+D   VL +V+L  +  M  +G V       D+ I + 
Sbjct: 135 ALEERQLIDSQRGQIAIGWLIVEDLVMVLTLVLLPAVAGMMEQGDVGFATLAVDMGITIG 194

Query: 184 EVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLA-EKFQLAGITGA 242
           +V  F  + +L+G  LV  ++  S      E  T   + + L  A+ A E F ++   GA
Sbjct: 195 KVIAFIAIMMLVGRRLVPWIMARSAATGSRELFTLSVLALALGVAFGAVELFDVSFALGA 254

Query: 243 YLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLIAV 302
           + AG++++ +E S +     + +    F  +F VS+G+  D  +L    +  L    I +
Sbjct: 255 FFAGMVLNESELSHRAAHDTLPL-RDAFAVLFFVSVGMLFDPLILIQQPLAVLATLAIIL 313

Query: 303 VGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVTMV 362
            GK +   F   +       A+ +   +    E A I+A +G+   +L +    + +   
Sbjct: 314 FGKSLAAFFLVRLFGHSQRTALTIAASLAQIGEFAFILAGLGMALNLLPQAGQNLVLAGA 373

Query: 363 VITTLITPFL 372
           +++ ++ P L
Sbjct: 374 ILSIMLNPVL 383


>gb|AAK40705.1| Na(+)/H(+) antiporter [Sulfolobus solfataricus]
           Length = 505
           
 Score =  104 bits (258), Expect = 1e-21
 Identities = 81/374 (21%), Positives = 168/374 (44%), Gaps = 16/374 (4%)

Query: 5   LELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVML 64
           L L I+L+ AKI   +  R+G    +G +L G+++G  +  V++    +  ++ LG+V L
Sbjct: 10  LYLGIMLIAAKISEEIFRRIGLVTFVGPILMGILLGNGVFGVIQINEIISFITSLGIVFL 69

Query: 65  LFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTATS 124
           LFLAG E +         + F+  ++   +PF +  +   + G+ +   L     L  +S
Sbjct: 70  LFLAGAE-EFNVENRPNANVFLAVILESIIPFSVILVAIYIIGFKNYLILIV--PLAMSS 126

Query: 125 VGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIILLE 184
            G  + +LMD+K    ++   I    I+ +++ +++  +L+  S        +I I ++E
Sbjct: 127 AGPLSRMLMDVKISDNRISNLIFQQVILIEIIFVILFAILLKTS--------EILITIIE 178

Query: 185 VAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGITGAYL 244
           + + F   I+ G  L K +  +       E      I I+LI  YLAE ++      A+ 
Sbjct: 179 IFLVFAFTIMFGRTLAKILEKIEYYFKAREIEFASLIAIILIIGYLAELYKFNSAISAFF 238

Query: 245 AGLLV-SMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLIAVV 303
            G+L+    +   ++ +++    Y  F P+F + IG+    ++     +F+L++  + + 
Sbjct: 239 LGILLKDYLKDRPELLERLHAFTYGFFEPLFFLGIGLYV-TKINASIILFSLLFFSLIIA 297

Query: 304 GKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVTMVV 363
            K +    G + ++   I+    G     +  V   +   GL  G +     +  +  + 
Sbjct: 298 SKFLA---GFISSKILNIKGKINGFATSVKGGVDSSLLLTGLTLGYINEFMYSFSILAIS 354

Query: 364 ITTLITPFLLKWAF 377
           ++ LI P L +  F
Sbjct: 355 LSALIVPLLFQINF 368


>pir||C70474 Na+/H+-exchanging protein - Aquifex aeolicus
           >gi|2984253|gb|AAC07780.1| (AE000768) Na(+)/H(+)
           antiporter [Aquifex aeolicus]
           Length = 422
           
 Score =  104 bits (256), Expect = 2e-21
 Identities = 68/334 (20%), Positives = 156/334 (46%), Gaps = 5/334 (1%)

Query: 9   IILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVMLLFLA 68
           ++L+   IFGY   ++  P+ +  ++ G +  P  L   E   +  +    G+++L F  
Sbjct: 16  LVLLFMFIFGYTFQKVNIPSIIAFMIIGFLAQP--LVPPEKIKDFEIFKHAGIILLFFFI 73

Query: 69  GLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTATSVGLT 128
           GLE   E  + + L A+    +     F+  ++++   G+  + AL    V   +S  + 
Sbjct: 74  GLEYSFERLRTM-LGAWKTGSIDFVFNFIPPFIIAYAFGFDLITALILAAVFYPSSTSII 132

Query: 129 TSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIILLEVAIF 188
             +LMD K++ +     ++   I +D++ I++LT+++ +   G +E   I + L+++ + 
Sbjct: 133 AKLLMDYKRIASPEAELLIGILIFEDLVAILLLTIIIPLKEAGSIEFTTIPVSLVKLGVA 192

Query: 189 FILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGITGAYLAGLL 248
           F+L  LI   L+ ++    +R++  +    F + ++L    +     ++   GA+L G++
Sbjct: 193 FLLFWLIYKYLIPKINAWLDRVSEEDIFIFFTLGLVLSIGTIFHSLGISEALGAFLLGVI 252

Query: 249 VSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLIAVVGKIIG 308
           V  T+    I  ++  +   L + +F      ET +    + G+  L+  ++ ++ KII 
Sbjct: 253 VPETKVLENIEKQLSDL-KELSMGLFFFFFAYETQLTKPENLGLLILLI-VLGIILKIIS 310

Query: 309 CGFGALVARFKPIEAIQVGIGMIPRMEVALIIAN 342
                 V   K    ++  +  +PR E ++I+ +
Sbjct: 311 TYLAGYVFGLKKKSRLRASLSFVPRGEFSVIMTS 344


>pir||B69146 gluthatione-regulated K+/H+ antiporter - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2621417|gb|AAB84864.1| (AE000821)
           gluthatione-regulated K+/H+ antiporter [Methanobacterium
           thermoautotrophicum]
           Length = 512
           
 Score =  103 bits (254), Expect = 4e-21
 Identities = 87/342 (25%), Positives = 159/342 (46%), Gaps = 11/342 (3%)

Query: 36  GVIIGPSLLDVVEYGSEVRLLSELGVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVP 95
           GVI GPS+L  V  GS +  L+ELGV++LLF  GLE   E F     +A I   + + + 
Sbjct: 3   GVIAGPSVLGAVSSGS-IESLAELGVILLLFTIGLEMSAERFGEFRRTALIGGTLQICLT 61

Query: 96  FLLGYLVSVLHGYGSLKALFFGGVLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDV 155
             +  +++++ G    KA+F G +++ +S  +   +L D  +     G   LA  I  DV
Sbjct: 62  VSVVTILTMVLGLSPGKAVFLGFLISLSSTAVVLKVLQDFHETEAPHGQASLAILIFQDV 121

Query: 156 LGIVILTLLVAMSSRGKVEVEDIEII--LLEVAIFFILGILIGHPLVKEVLTLSERITLP 213
             +    +++ +   G V  +    +  LL           IG  LV  +  +       
Sbjct: 122 AAV---PMILTVPFLGGVVGDPSSALGTLLTAGAVLPWEPCIGKVLVPRLFDVVAATGSR 178

Query: 214 ETVTTFAIVIMLIFAYLAEKFQLAGITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPI 273
           E      I++     +L  +  L+   GA+L G +V+ TE + +    I+     +F+  
Sbjct: 179 EIFLLTVILVCASVTWLTGEVGLSPALGAFLVGSIVANTEYAHRAQGTILPF-QEVFLSF 237

Query: 274 FLVSIGIETDIR-VLTHAGVFALVYSLIAVVG-KIIGCGFGALVARFKPIEAIQVGIGMI 331
           F VS+G+  D+R  L H  ++ +V ++I V+  K++       V  +     + +G+ + 
Sbjct: 238 FFVSLGMLLDLRFFLDH--IYLIVLAVIGVLMIKVVMNSLVGFVMGYSARVVVLLGLVLA 295

Query: 332 PRMEVALIIANVGLKEGILTRGDLAVPVTMVVITTLITPFLL 373
              E + I++  GL+ G++ R      +++ +IT  ITPFL+
Sbjct: 296 QIGEFSFILSETGLRYGLMDRLTFQAFLSVSLITMAITPFLI 337


>pir||G75282 probable glutathione-regulated potassium-efflux system protein KefB
           - Deinococcus radiodurans (strain R1)
           >gi|6460182|gb|AAF11914.1|AE002067_6 (AE002067)
           glutathione-regulated potassium-efflux system protein
           KefB, putative [Deinococcus radiodurans]
           Length = 575
           
 Score =  102 bits (251), Expect = 9e-21
 Identities = 80/306 (26%), Positives = 145/306 (47%), Gaps = 10/306 (3%)

Query: 6   ELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVMLL 65
           +L ++L++A    + S RLG    +G L  GV+ GPS L +++  + +   SE+GV++LL
Sbjct: 38  QLTLLLLVAGATAFASFRLGLVPIIGFLFAGVLAGPSALGIIDDPALIGAASEIGVMLLL 97

Query: 66  FLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTATSV 125
           F  G+E  +++   +    F+   + V +       V +  G     A+F G +L+ +S 
Sbjct: 98  FTIGIEFSLDKLARIFRLIFVGGGLQVLLTVAAVTGVLLAFGVSLPNAVFTGFLLSLSST 157

Query: 126 GLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIILLEV 185
            + T IL     + +  G   L   I  D L +V++ LLV M +        + + LL+ 
Sbjct: 158 AIVTKILESRGGVGSPTGQASLGILIFQD-LAVVVMVLLVPMLAGQGGGAGGLVVALLKA 216

Query: 186 AIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGITGAYLA 245
                  +L+   +V ++L +  R    E      + +    AYL     ++   GA+LA
Sbjct: 217 GGIVAAVLLLARRVVPKLLEVVARTCSQEIFLLSTLSLCFATAYLTSLAGVSLALGAFLA 276

Query: 246 GLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVL-TH-------AGVFALVY 297
           GLLVS +   ++   +I+ +   LF   F +S+G++ D+  L TH         VFA++ 
Sbjct: 277 GLLVSESRFGQQAFGEILPL-QILFSAAFFLSVGLQLDLGFLWTHLPLVLGAVAVFAVLK 335

Query: 298 SLIAVV 303
           +L A +
Sbjct: 336 ALAAAL 341


>pir||G75431 probable Na+/H+ antiporter - Deinococcus radiodurans (strain R1)
           >gi|6458886|gb|AAF10721.1|AE001964_5 (AE001964) Na+/H+
           antiporter, putative [Deinococcus radiodurans]
           Length = 383
           
 Score =  101 bits (250), Expect = 1e-20
 Identities = 92/378 (24%), Positives = 180/378 (47%), Gaps = 18/378 (4%)

Query: 3   VFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGP--SLLDVVEYGSEVRLLSELG 60
           +FLEL  +++   + G  + RLG       L+ G+ +G    L D  E    +   +E+G
Sbjct: 5   LFLELGTVILALALVGRAAGRLGITPIPLYLMAGIGLGTFMHLDDTAE--KFIHTGAEIG 62

Query: 61  VVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVL 120
            ++LLF+ GLE   +E +    +   + ++ + + F  G +   L G   L  +  GG+ 
Sbjct: 63  AILLLFILGLEYTSDELRTNLKANRQIGLIDLALNFTPGVVAGALLGLPPLAWVLLGGIT 122

Query: 121 TATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEI 180
             TS G+ + IL D+ +L  +    ILA  +++DV+    L ++ A+   G +    + +
Sbjct: 123 FLTSSGIASKILSDLGRLGNRETPIILAVCVIEDVVMAFYLPVVAALLIGGSLLSVGVNL 182

Query: 181 ILLEVA--IFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAG 238
            L   A  + F L +  GH     VL+    +   ET+    + ++L+ A  A+  +++ 
Sbjct: 183 ALALTAFGVTFFLAMRYGH-----VLSRVLNVPSDETLLLGVLGLVLVVAGAADLLKVSA 237

Query: 239 ITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYS 298
             GA+L G+ +S  E + +   +I  +   LF  +F +  G++ D+  +    + A + +
Sbjct: 238 AIGAFLVGIALS-GEVAHRARQQIEPL-RDLFAAVFFLFFGLQLDLAEVPEVLLPAALLA 295

Query: 299 LIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGIL-TRGDLAV 357
           ++  + K +   +GA  A  +     + G  +I R E +++IA +GL  G+    G LA 
Sbjct: 296 VVTSITKFLVGWYGARRAGVQSRGRYRAGTTLIARGEFSILIAGLGL--GLAPVLGPLA- 352

Query: 358 PVTMVVITTLITPFLLKW 375
               V++T +I P L ++
Sbjct: 353 -AVYVLLTAIIGPVLARF 369


>pir||G70337 Na+/H+-exchanging protein - Aquifex aeolicus
           >gi|2983090|gb|AAC06696.1| (AE000689) NA(+)/H(+)
           antiporter [Aquifex aeolicus]
           Length = 387
           
 Score =  101 bits (248), Expect = 2e-20
 Identities = 92/382 (24%), Positives = 175/382 (45%), Gaps = 13/382 (3%)

Query: 5   LELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVML 64
           L L I+ + A +    S  L  P  +G+L+ G++IG   + + +    +  LS+ G ++L
Sbjct: 11  LFLIIVFLSAFLAPLFSRILRMPVPVGELIFGILIGNFFVGI-QVPEILNFLSDFGFLLL 69

Query: 65  LFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTATS 124
           +FLAGLE D    +        V +  V + FL  ++  +L G G+  A+    +L+  S
Sbjct: 70  MFLAGLELDFNLIEKADKKQNAVYISYVLLIFLSAFVFGILLGIGTAPAI----ILSLIS 125

Query: 125 VGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLL-VAMSSRGKVE-VEDIEIIL 182
           +GL  + L DM  L       +L   +  +++ ++ LTL+   +   G V  ++++ +I 
Sbjct: 126 LGLMVATLKDMSVLEEPFAKKVLLIGVFGEIISLLALTLMEKLLHFHGFVSLIKELGVIF 185

Query: 183 LEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKF-QLAGI-- 239
           +    FF LG  +   LV     +  R+T  E  +   I + L   + +  F +LAGI  
Sbjct: 186 VFFFSFF-LGFYLTRLLVWWYPEIVNRLTYEEDPSALGIRLSLFLMFTSSIFAKLAGIES 244

Query: 240 -TGAYLAGLLVSMTEGSRK-ITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVY 297
             GA++AG++ S     +K + +K+ +IGY   IPIF +  G+  ++  L  A +F +  
Sbjct: 245 VLGAFMAGVVFSYFIREKKDLEEKLSSIGYGFLIPIFFIKTGMGMEVAGLNLAILFKVFI 304

Query: 298 SLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAV 357
            L  ++   +   F  L+A F   ++   G+ +     + +    +  + G L       
Sbjct: 305 FLAFMLFVRLIPSFVLLLAGFSLKDSFTAGLLLSYPFTLMVAGIEIARRGGALDEETALA 364

Query: 358 PVTMVVITTLITPFLLKWAFSK 379
                  ++L+ P+  K   S+
Sbjct: 365 LFLTAAFSSLVFPWSAKIILSR 386


>sp|P44933|KEFX_HAEIN GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYSTEM PROTEIN (K(+)/H(+)
           ANTIPORTER) >gi|1075164|pir||A64102
           glutathione-regulated potassium efflux system protein
           kefC homolog - Haemophilus influenzae (strain Rd KW20)
           >gi|1573928|gb|AAC22568.1| (U32772)
           glutathione-regulated potassium efflux system protein
           (kefC) [Haemophilus influenzae Rd]
           Length = 618
           
 Score =  100 bits (247), Expect = 3e-20
 Identities = 87/382 (22%), Positives = 174/382 (44%), Gaps = 15/382 (3%)

Query: 1   MEVFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELG 60
           M+V + LA  + I  +F     RLG  + LG L+ G +IGPS+  +V+  + V  L+ELG
Sbjct: 10  MKVVILLASSVTIVPLFK----RLGLGSVLGYLVAGCLIGPSVFGIVQEPTAVVHLAELG 65

Query: 61  VVMLLFLAGLETDVEEFKHV-----GLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALF 115
           VVM LF+ GLE   E    +     G     V + G  + F   YL+ +      +  + 
Sbjct: 66  VVMFLFIIGLEMYPERLWAMRKAIFGRGLLQVGLCGCLLTFSGIYLLGLTKEVSFIAGMG 125

Query: 116 FGGVLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEV 175
           F    T +S  +    L +     T  G  +++  I +D+  + +L  +  ++   K   
Sbjct: 126 F----TLSSTAIVMQSLEERGLTSTSKGQRVISTLIFEDIAIVPLLASVAFLAPHSKEAT 181

Query: 176 EDIEIILLEVAIFFILGILI-GHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKF 234
              + + + +A+  ++G+++ G  L+  +  L  +  + E +T  A++++L  A   E  
Sbjct: 182 PHTDWVSIGIALSAVVGLIVTGKWLMNPLFRLISKARIREMMTAGALLVVLGAALAMEIG 241

Query: 235 QLAGITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFA 294
            L+   GA++AG+++S +    ++   I      L + +F + +G+  D+ ++ +  +  
Sbjct: 242 GLSMAMGAFVAGVMMSESAFRHQLEADIEPF-RGLLLGLFFMGVGMSLDLHLVFNHWILL 300

Query: 295 LVYSLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGD 354
           L    + ++GK       A + R    EAI     M    E A ++ +      +++  +
Sbjct: 301 LGIVFLYILGKASAVYIIARITRLDHREAIGRMSLMAHGGEFAFVLFSAAATAEVISNEE 360

Query: 355 LAVPVTMVVITTLITPFLLKWA 376
            A     V+I+ L +P + + A
Sbjct: 361 QATFTAAVIISMLFSPIIAQIA 382


>dbj|BAA06982.1| (D32253) MagA [Magnetospirillum sp.]
           Length = 434
           
 Score = 99.5 bits (244), Expect = 6e-20
 Identities = 83/375 (22%), Positives = 177/375 (47%), Gaps = 14/375 (3%)

Query: 8   AIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVMLLFL 67
           AI+ + A + G +  RL  PA +G +L GV++GPS   +V     V  L+E GV+MLLF+
Sbjct: 12  AIVALAAVLCGGMMTRLKQPAVVGYILAGVVLGPSGFGLVSNRDAVATLAEFGVLMLLFV 71

Query: 68  AGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYG-SL-KALFFGGVLTATSV 125
            G++ D+  F  V  +A    V+   +   +G  + + HG G SL  A+  G  +  +S 
Sbjct: 72  IGMKLDIIRFLEVWKTAIFTTVLQ--IAGSVGTALLLRHGLGWSLGLAVVLGCAVAVSST 129

Query: 126 GLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIILLEV 185
            +   +L    +L T VG T L   I  D+  + ++ +L +  ++  +  +   ++L   
Sbjct: 130 AVVIKVLESSDELDTPVGRTTLGILIAQDMAVVPMMLVLESFETKALLPADMARVVL--- 186

Query: 186 AIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLI-FAYLAEKFQLAGITGAYL 244
           ++ F++ +       +  L ++ R++    + T + +      A ++    L+   GA+L
Sbjct: 187 SVLFLVLLFWWLSKRRIDLPITARLSRDSDLATLSTLAWCFGTAAISGVLDLSPAYGAFL 246

Query: 245 AGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIR-VLTHAGVFALVYSLIAVV 303
            G+++  +     +  +   IG S+ + +F +SIG+  D + +  + G    + +++ + 
Sbjct: 247 GGVVLGNSAQRDMLLKRAQPIG-SVLLMVFFLSIGLLLDFKFIWKNLGTVLTLLAMVTLF 305

Query: 304 GKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVTMVV 363
              +      L  +  P  A   G+ +    E + ++A  G    +++  +  + V + V
Sbjct: 306 KTALNVTALRLARQDWP-SAFLAGVALAQIGEFSFLLAETGKAVKLISAQETKLVVAVTV 364

Query: 364 ITTLITPFLLKWAFS 378
           ++ +++PF   W F+
Sbjct: 365 LSLVLSPF---WLFT 376


>pir||A81330 probable glutathione-regulated potassium-efflux system protein
           Cj1231 [imported] - Campylobacter jejuni (strain NCTC
           11168) >gi|6968664|emb|CAB73485.1| (AL139077) putative
           glutathione-regulated potassium-efflux system protein
           [Campylobacter jejuni]
           Length = 541
           
 Score = 99.1 bits (243), Expect = 8e-20
 Identities = 91/378 (24%), Positives = 167/378 (44%), Gaps = 12/378 (3%)

Query: 1   MEVFLELAIILV-IAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSEL 59
           M+ FLE+ +I V IA +   +  +   P  +G +  G II  S +  +    E+  ++E 
Sbjct: 1   MDNFLEIFLITVAIAIVLNVIFKKFEIPTIIGYIAAGEII--SEIYHLSGKGEITHIAEF 58

Query: 60  GVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLH----GYGSLKALF 115
           G+V L+F  GLE     FKH+      V + G       G++  +L     G G   A  
Sbjct: 59  GIVFLMFTIGLEFS---FKHLMAMKQEVFLNGSLQMLTCGFVFMLLAIGILGLGDKSATI 115

Query: 116 FGGVLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEV 175
            G  L  +S  +   IL D   +  + G   L   +  D+  I +L L+   SS  +   
Sbjct: 116 VGFALALSSTAVVLKILNDNGDINEQYGRKALGILLFQDIAVIPLLLLVDIFSSNNQNIE 175

Query: 176 EDIEIILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQ 235
           + +   L+   I   L   IG  LV  +  L    +  E   +  + +++  ++LA  F 
Sbjct: 176 KLLFTSLISALILITLLFFIGKYLVDRIFRLIIHTSSQEIFISTVLFMVIGASFLANYFG 235

Query: 236 LAGITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFAL 295
            +   GA++AG L++ T+   KI   ++     L + +F +++G++  + V+       +
Sbjct: 236 FSYSLGAFIAGALIAETKYKHKIEADLIPF-RDLLLGLFFITVGMQIQLDVVAQNWFLII 294

Query: 296 VYSLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDL 355
           V +L+ +  K  G  FG L    K   A++    +    E AL I ++   + +L     
Sbjct: 295 VLTLLVMALK-FGIVFGFLFLYTKKRVALKTAFAIAQIGEFALAIFSLLQAKNMLDIKTS 353

Query: 356 AVPVTMVVITTLITPFLL 373
            + + + ++T +ITPF+L
Sbjct: 354 QILIVVSILTMIITPFIL 371


>gb|AAD01191.1| (AF003382) KEA1 [Arabidopsis thaliana]
           Length = 618
           
 Score = 98.7 bits (242), Expect = 1e-19
 Identities = 97/386 (25%), Positives = 177/386 (45%), Gaps = 38/386 (9%)

Query: 10  ILVIAKIFGYLSVRL-GFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVMLLFLA 68
           +L+ + IF  L  ++ G    LG L  G++IGP  L ++      R ++E GVV+LLF  
Sbjct: 20  LLLASVIFVPLFQKIPGGSPVLGYLAAGILIGPYGLSIIRNVHGTRAIAEFGVVLLLFNI 79

Query: 69  GLETDVEEFKHVGLSAFIVAVMGVFV-PFLLGYLVSVLHGYGSLKALFFGGVLTATSVGL 127
           GLE  VE    +    F +    V V   ++G L   + G     A+  G  L  +S  +
Sbjct: 80  GLELSVERLSSMKKYVFGLGSAQVLVTAAVVGLLAHYVAGQAGPAAIVIGNGLALSSTAV 139

Query: 128 TTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAM----SSRGKV------EVED 177
              +L +  +  ++ G    +  +  D L +V+L +L+ +    SS+G +      E   
Sbjct: 140 VLQVLQERGESTSRHGRASFSVLLFQD-LAVVVLLILIPLISPNSSKGGIGFQAIAEALG 198

Query: 178 IEIILLEVAIFFIL--GILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQ 235
           +  +   VAI  I+  G L+  P+ K++          E  +   ++++L  + L  +  
Sbjct: 199 LAAVKAAVAITAIIAGGRLLLRPIYKQIAENRN----AEIFSANTLLVILGTSLLTARAG 254

Query: 236 LAGITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTH-----A 290
           L+   GA+LAGLL++ TE S ++   I      L + +F +++G+  D ++L        
Sbjct: 255 LSMALGAFLAGLLLAETEFSLQVESDIAPY-RGLLLGLFFMTVGMSIDPKLLLSNFPVIV 313

Query: 291 GVFALVY----SLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLK 346
           G   L+      L+ ++GK+ G            I AI+VG+ + P  E A +     + 
Sbjct: 314 GTLGLLIVGKTMLVVIMGKLFGISI---------ISAIRVGLLLAPGGEFAFVAFGEAVN 364

Query: 347 EGILTRGDLAVPVTMVVITTLITPFL 372
           +GI++    ++   +V I+  ITP+L
Sbjct: 365 QGIMSPQLSSLLFLVVGISMAITPWL 390


>gb|AAF78418.1|AC009273_24 (AC009273) Identical to K efflux antiporter mRNA from Arabidopsis
           thaliana gb|AF003382. It contains a TrkA potassium
           uptake protein PF|02080 domain.  ESTs gb|T44799,
           gb|AA395270 and gb|AI997899 come from this gene
           Length = 618
           
 Score = 97.9 bits (240), Expect = 2e-19
 Identities = 97/386 (25%), Positives = 176/386 (45%), Gaps = 38/386 (9%)

Query: 10  ILVIAKIFGYLSVRL-GFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVMLLFLA 68
           +L+ + IF  L  ++ G    LG L  G++IGP  L ++      R ++E GVV LLF  
Sbjct: 20  LLLASVIFVPLFQKIPGGSPVLGYLAAGILIGPYGLSIIRNVHGTRAIAEFGVVFLLFNI 79

Query: 69  GLETDVEEFKHVGLSAFIVAVMGVFV-PFLLGYLVSVLHGYGSLKALFFGGVLTATSVGL 127
           GLE  VE    +    F +    V V   ++G L   + G     A+  G  L  +S  +
Sbjct: 80  GLELSVERLSSMKKYVFGLGSAQVLVTAAVVGLLAHYVAGQAGPAAIVIGNGLALSSTAV 139

Query: 128 TTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAM----SSRGKV------EVED 177
              +L +  +  ++ G    +  +  D L +V+L +L+ +    SS+G +      E   
Sbjct: 140 VLQVLQERGESTSRHGRASFSVLLFQD-LAVVVLLILIPLISPNSSKGGIGFQAIAEALG 198

Query: 178 IEIILLEVAIFFIL--GILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQ 235
           +  +   VAI  I+  G L+  P+ K++          E  +   ++++L  + L  +  
Sbjct: 199 LAAVKAAVAITAIIAGGRLLLRPIYKQIAENRN----AEIFSANTLLVILGTSLLTARAG 254

Query: 236 LAGITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTH-----A 290
           L+   GA+LAGLL++ TE S ++   I      L + +F +++G+  D ++L        
Sbjct: 255 LSMALGAFLAGLLLAETEFSLQVESDIAPY-RGLLLGLFFMTVGMSIDPKLLLSNFPVIV 313

Query: 291 GVFALVY----SLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLK 346
           G   L+      L+ ++GK+ G            I AI+VG+ + P  E A +     + 
Sbjct: 314 GTLGLLIVGKTMLVVIMGKLFGISI---------ISAIRVGLLLAPGGEFAFVAFGEAVN 364

Query: 347 EGILTRGDLAVPVTMVVITTLITPFL 372
           +GI++    ++   +V I+  ITP+L
Sbjct: 365 QGIMSPQLSSLLFLVVGISMAITPWL 390


>pir||E82956 probable potassium efflux transporter PA5518 [imported] -
           Pseudomonas aeruginosa (strain PAO1)
           >gi|9951855|gb|AAG08903.1|AE004964_6 (AE004964) probable
           potassium efflux transporter [Pseudomonas aeruginosa]
           Length = 567
           
 Score = 97.1 bits (238), Expect = 3e-19
 Identities = 97/375 (25%), Positives = 168/375 (43%), Gaps = 10/375 (2%)

Query: 7   LAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVMLLF 66
           LA   V+A +FG L+ RL     +G LL GV+ GP     V   +  + ++ELGV++L+F
Sbjct: 10  LAAGFVLAFLFGALANRLRISPLVGYLLAGVLAGPFTPGYVADQALSQEIAELGVILLMF 69

Query: 67  LAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTATSVG 126
             GL   +++   V   A   A++ + V  LLG  ++ L G+     L FG  L+  S  
Sbjct: 70  GVGLHFSLKDLLSVKAIAIPGALVQIGVATLLGIGLAKLLGWSFGGGLVFGLSLSVASTV 129

Query: 127 LTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSR--GKVEVED------I 178
           +    L   + L TK G   +   IV+D+  ++ L LL A++    GK +  D      +
Sbjct: 130 VLLRALEQRQLLDTKRGRIAIGWLIVEDLAMVLTLVLLPALAGTLGGKTDGGDAGLLWPL 189

Query: 179 EIILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAY-LAEKFQLA 237
            I L +VA F  L I  G  +V  VL         E  T   + I L  AY  A  F ++
Sbjct: 190 LITLGKVAAFVALMIFGGRRVVPWVLERIAASGSRELFTLAVLAIALGIAYGSAVLFGVS 249

Query: 238 GITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVY 297
              GA+ AG++++ +E S +  +  + +    F  +F VS+G+  +  +L    +  L  
Sbjct: 250 FALGAFFAGMILNESELSHEAAENSLPL-RDAFAVLFFVSVGMLFNPMILLQEPLTVLAT 308

Query: 298 SLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAV 357
            L+ V GK +               A+ +   +    E + I+  +G+   ++      +
Sbjct: 309 FLVIVFGKSVAAYLIVRAFGHPNSTALVIAASLAQIGEFSFILIGLGIGLELVPEQSRDL 368

Query: 358 PVTMVVITTLITPFL 372
            +   +++ L+ P L
Sbjct: 369 VLAGAILSILVNPLL 383


>gb|AAC60780.1| (U46859) RosB [Yersinia enterocolitica (type 0:8)]
           Length = 563
           
 Score = 96.7 bits (237), Expect = 4e-19
 Identities = 89/370 (24%), Positives = 164/370 (44%), Gaps = 9/370 (2%)

Query: 11  LVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVMLLFLAGL 70
           LV+A + G L+ RL     +G L  GV+ GP     V   S    L+E+GV++L+F  GL
Sbjct: 15  LVLAFLLGSLAHRLRSSPLVGYLAAGVLAGPFTPGFVADTSLAPELAEIGVILLMFGVGL 74

Query: 71  ETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTATSVGLTTS 130
              +++   V   A   AV  + V  LLG  +S L G+  +    FG  L+  S  +   
Sbjct: 75  HFSLKDLLAVKAIAIPGAVAQIAVATLLGMGLSHLLGWDLMTGFVFGLCLSTASTVVLLR 134

Query: 131 ILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIILLEVAI--- 187
            L + + + ++ G   +  +IV+D+  ++ L LL A +     E   +  +  E+AI   
Sbjct: 135 ALEERQLIDSQRGQIAIGRSIVEDLAMVLTLVLLPAFAGVMGNETTSLSQLFTELAITIG 194

Query: 188 ----FFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLA-EKFQLAGITGA 242
               F  L I++G  LV  +L  +      E  T   +V+ L  AY A   F ++   GA
Sbjct: 195 KVIAFITLMIVVGRRLVPWILAKTASTGSRELFTLAVLVLALGIAYGAVGLFDVSFALGA 254

Query: 243 YLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLIAV 302
           + AG++++ +E S +     + +    F  +F VS+G+  D  +L    +  L    I +
Sbjct: 255 FFAGMVLNESELSHRAAQDTLPL-RDAFAVLFFVSVGMLFDPMILLREPLAVLASLAIII 313

Query: 303 VGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVTMV 362
            GK         +     + +          + +  I+A +G+  G+++     + +   
Sbjct: 314 FGKSAAAFILVRMFGHSNVYSTHHFCPWRKSVNLPFILAGLGISLGLMSEHGRNLVLAGA 373

Query: 363 VITTLITPFL 372
           +++ ++ P L
Sbjct: 374 ILSIMLNPLL 383


>pir||G69819 Na+/H+ antiporter homolog yhaU - Bacillus subtilis
           >gi|2226151|emb|CAA74453.1| (Y14080) hypothetical
           protein [Bacillus subtilis] >gi|2633321|emb|CAB12825.1|
           (Z99109) similar to Na+/H+ antiporter [Bacillus
           subtilis]
           Length = 408
           
 Score = 96.7 bits (237), Expect = 4e-19
 Identities = 80/351 (22%), Positives = 149/351 (41%), Gaps = 9/351 (2%)

Query: 6   ELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSL-------LDVVEYGSEVRLLSE 58
           E+   LV+  I   ++ ++ F      ++ G+++GP         L  ++    +     
Sbjct: 10  EVGTALVLVAIASVIANKIKFSIIPFLIVLGMLVGPHAPKMGIIDLTFIQSSEIIEFFGR 69

Query: 59  LGVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGG 118
           +GV+ LLF  GLE  V +    G S  +   + + + F LG L   + G+  L+ L   G
Sbjct: 70  MGVLFLLFYLGLEFSVGKLIKSGKSIAVGGTIYILINFSLGLLYGFITGFSFLEVLILAG 129

Query: 119 VLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDI 178
           V+T +S  +   +L+D+K+        IL   + +D+   V L+++  +       V   
Sbjct: 130 VITISSSAIVAKVLVDLKRTANPETELILGIIMFEDIFLAVYLSVVSGLILGDATSVGSA 189

Query: 179 EIILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAG 238
            + +L +A  ++L   I    +  +L     I   E         +   A  +E   +A 
Sbjct: 190 LLSIL-IAFGYMLLFFIAARKLPPLLNKLLDIRSNEVFIIVIFAALFFIAGFSETIHVAE 248

Query: 239 ITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYS 298
             GA L GL+ S TE S +I   ++      F  +F  S G+  D   L  A   AL   
Sbjct: 249 AIGALLLGLVFSETEHSDRIEHLVVPF-RDFFGAMFFFSFGLSIDPFSLGEAVWLALGAV 307

Query: 299 LIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGI 349
           ++ ++G  I        A      +  +G+ ++ R E ++I+AN+G+  G+
Sbjct: 308 ILTILGNFIAGMVAGRRAGLSHKASSNIGLTIVSRGEFSIIVANLGIAGGL 358


>pir||B82056 glutathione-regulated potassium-efflux system protein KefB VC2606
           [imported] - Vibrio cholerae (group O1 strain N16961)
           >gi|9657194|gb|AAF95747.1| (AE004327)
           glutathione-regulated potassium-efflux system protein
           KefB [Vibrio cholerae]
           Length = 656
           
 Score = 96.0 bits (235), Expect = 7e-19
 Identities = 95/377 (25%), Positives = 174/377 (45%), Gaps = 18/377 (4%)

Query: 4   FLELAIILVIAKIFGY-LSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVV 62
           FL  +++ + A +    L+ R G  + LG LL G+ IGP  L ++     +   +E GVV
Sbjct: 64  FLSSSVVFLSAAVIAVPLAQRAGLGSVLGYLLAGIAIGPWGLGLIRDVQAIMHFAEFGVV 123

Query: 63  MLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSV--LHGYGSLKALFFGGVL 120
           +LLFL GLE + +  K   L   I+ + G  V      L SV  L G     AL  G  L
Sbjct: 124 LLLFLIGLELNPK--KLWNLRGPILGLGGAQVVVTTAVLSSVAYLLGVSWQSALVIGMAL 181

Query: 121 TATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEI 180
             +S  +   ++ +    RT+ G +  A  +  D+  I +L LL  ++     +  +   
Sbjct: 182 ALSSTAIALRVIEEHGLTRTEAGQSGFAVLLFQDIAVIPMLALLPILAGNSSGDWLNALW 241

Query: 181 ILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGIT 240
           +   +A   + G  + +PL + +     R    E  T  A+++++  A L +K  L+   
Sbjct: 242 MTGGIAALLLGGHFLLNPLFRYIALSGVR----ELFTVAALLLVVGIALLMQKVGLSMAL 297

Query: 241 GAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLI 300
           G +LAG++++ +E   ++   I      L + +F +S+G+  D+ +L    +   +  ++
Sbjct: 298 GTFLAGVILAESEFRHELEIAIDPF-KGLLLGLFFISVGMAVDVGLL----LVKPLQIML 352

Query: 301 AVVGKIIGCGFGA-LVARFKPIEA---IQVGIGMIPRMEVALIIANVGLKEGILTRGDLA 356
           AV+G +I  G    L+AR     A    ++   +    E A +I      EG+LT   ++
Sbjct: 353 AVLGLVIVKGLVLYLLARLSGTVAKARSKMAAILSQGGEFAFVIFTAASAEGLLTASQVS 412

Query: 357 VPVTMVVITTLITPFLL 373
             + +V ++ + TP LL
Sbjct: 413 FLLVVVSLSMVTTPLLL 429


>dbj|BAB11240.1| (AB010074) potassium/proton antiporter-like protein [Arabidopsis
           thaliana]
           Length = 562
           
 Score = 94.8 bits (232), Expect = 1e-18
 Identities = 88/381 (23%), Positives = 178/381 (46%), Gaps = 11/381 (2%)

Query: 1   MEVFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELG 60
           + +  +L +I+V A I G +   LG P  +G LL G IIGP  L  +    +V  +++ G
Sbjct: 152 LRLISDLVVIIVFAAIGGIVFSCLGQPVIVGYLLAGSIIGPGGLKFISEMVQVETVAQFG 211

Query: 61  VVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVL 120
           VV LLF  GLE  + + K VG  A +  ++ + +   L  + ++L G    + +F G  L
Sbjct: 212 VVFLLFALGLEFSMTKLKVVGPVAVLGGLLQIVLLMFLCGVTALLCGARLSEGIFVGAFL 271

Query: 121 TATSVGLTTSILMDMKKLRTKVGTTILAAAIVDD-VLGIVILTLLVAMSSRGKVE-VEDI 178
           + +S  +    L++     +  G   +   I  D V+G++   L V   + G ++ +  +
Sbjct: 272 SMSSTAVVVKFLVERNSTSSLHGQVTIGILIFQDCVVGLLFALLPVLGGNSGLLQGIISM 331

Query: 179 EIILLEVAIFFILGILIGHPLVKEVLTLSERIT--LPETVTTFAIVIMLIFAYLAEKFQL 236
             +LL ++I+  +  L+    V   L L  +++    E     A+   L+ A+ ++K  L
Sbjct: 332 GKLLLILSIYLTVASLLTWSFVPRFLKLMIQLSSQTNELYQLAAVAFCLLSAWCSDKLGL 391

Query: 237 AGITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALV 296
           +   G+++AG+++S TE ++   ++++ +    F       IG+  ++  L +  V  L+
Sbjct: 392 SLELGSFVAGVMLSTTEFAQHTLEQVLILNSGRFC-FASTCIGMLINVHFLWN-HVDILL 449

Query: 297 YSLIAVVGKIIGCGFGALVA---RFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRG 353
            S+I V+  +I     A+V    R+    +  VG+ +    E A ++ +      ++   
Sbjct: 450 ASVILVI--VIKTAIAAVVVKAFRYNMRISFHVGVLLAQIGEFAFVLLSRASNLHVIEGK 507

Query: 354 DLAVPVTMVVITTLITPFLLK 374
              + +    ++ + TP L K
Sbjct: 508 MYLLLLGTTALSLVTTPLLFK 528


>sp|P03819|KEFC_ECOLI GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYSTEM PROTEIN KEFC
           (K(+)/H(+) ANTIPORTER) >gi|2145008|pir||QQECRD
           glutathione-regulated potassium efflux system protein
           kefC [validated] - Escherichia coli
           >gi|41875|emb|CAA40066.1| (X56742) KefC potassium efflux
            system [Escherichia coli] >gi|216472|dbj|BAA01323.1|
           (D10483) kefc potassium efflux system [Escherichia coli]
           >gi|1786232|gb|AAC73158.1| (AE000115) K+ efflux
           antiporter, glutathione-regulated [Escherichia coli K12]
           Length = 620
           
 Score = 94.4 bits (231), Expect = 2e-18
 Identities = 74/285 (25%), Positives = 134/285 (46%), Gaps = 4/285 (1%)

Query: 5   LELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVML 64
           ++  I L  A +   ++VRLG  + LG L+ G IIGP  L +V     +   +E+GVV++
Sbjct: 7   IQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLM 66

Query: 65  LFLAGLETDVEEFKHVGLSAF-IVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTAT 123
           LF+ GLE D +    +  + F   A+  V    LLG L  +L G     A   G  L  +
Sbjct: 67  LFIIGLELDPQRLWKLRAAVFGCGALQMVICGGLLG-LFCMLLGLRWQVAELIGMTLALS 125

Query: 124 SVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLL-VAMSSRGKVEVEDIEIIL 182
           S  +    + +   + T++G +  A  +  D+  I ++ ++ +  +S     +    +  
Sbjct: 126 STAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAIPLVAMIPLLATSSASTTMGAFALSA 185

Query: 183 LEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGITGA 242
           L+VA   +L +L+G  + +  L    R  L E  +  A+ ++  F  L E+  L+   GA
Sbjct: 186 LKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGA 245

Query: 243 YLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVL 287
           +LAG+L++ +E    +   I      L + +F + +G+  D   L
Sbjct: 246 FLAGVLLASSEYRHALESDIEPF-KGLLLGLFFIGVGMSIDFGTL 289


>pir||G64578 glutathione-regulated potassium-efflux system protein -
           Helicobacter pylori (strain 26695)
           >gi|2313582|gb|AAD07539.1| (AE000562)
           glutathione-regulated potassium-efflux system protein
           (kefB) [Helicobacter pylori 26695]
           Length = 416
           
 Score = 93.6 bits (229), Expect = 3e-18
 Identities = 90/396 (22%), Positives = 182/396 (45%), Gaps = 44/396 (11%)

Query: 11  LVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSL-LDVVEYGSEVRLLSELGVVMLLFLAG 69
           L +A  FG    +L  P  +G +  G ++     ++  +  S++    E G+V L+F+ G
Sbjct: 13  LWLAVGFGIFLKKLDMPVIIGYICTGTVLAAFFKINDFDLLSDI---GEFGIVFLMFMIG 69

Query: 70  LETDVEEFKHVGLSAFIVAVMGV----FVPFLLGYLVSVLHGYGSLKALFFGGVLTATSV 125
           +E + ++ K +     +  ++ V     + FLLGY V    G   + +L  G  L+ +S 
Sbjct: 70  IEFNFDKLKSIKQEVLVFGLLQVVLCALIAFLLGYFVL---GLSPIFSLVLGMGLSLSST 126

Query: 126 GLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIILLE- 184
            +      D K+L T +G + +   I  D+  I +L +L  + S+      ++ +++L+ 
Sbjct: 127 AIVLKFFEDSKQLSTPMGKSAVGILIFQDIAAIPMLLILTILGSKD----SNVNLLILKT 182

Query: 185 ---VAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGITG 241
                I  +L +L G      +L  ++   LPE      +VI+   A L+  F  +   G
Sbjct: 183 FISAGIILVLLLLPGKKGANLILEQAKDTRLPEIFIGTILVIVCSAAGLSHFFGFSMSLG 242

Query: 242 AYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLIA 301
           A++ G+ +S +     + ++   +  +LF+ +F ++IG++ ++        F +++ LI 
Sbjct: 243 AFIVGMAISKSRYKINVQEEFAQL-KNLFLALFFITIGMQINVSFFMEK-FFVVIFLLIL 300

Query: 302 VVGKIIGCGFGALVARFKPIE-AIQVGIGMIPRMEVALII---------ANVGLKEGIL- 350
           V+G      + AL+  F+  + AI+  + +    E + +I          N+  K+GIL 
Sbjct: 301 VMGFKTAIIY-ALLRFFRDAKTAIKTALSLAQIGEFSFVIFLNSGSHQLFNLQEKKGILG 359

Query: 351 ----------TRGDL-AVPVTMVVITTLITPFLLKW 375
                      + D+  + + MVV + L TPF+LK+
Sbjct: 360 FLHQKNILNIAQNDIHQLLILMVVFSMLATPFILKY 395


>pir||T35370 probable transmembrane transport protein - Streptomyces coelicolor
           >gi|5123877|emb|CAB45469.1| (AL079348) putative
           transmembrane transport protein [Streptomyces coelicolor
           A3(2)]
           Length = 403
           
 Score = 92.8 bits (227), Expect = 6e-18
 Identities = 82/366 (22%), Positives = 171/366 (46%), Gaps = 13/366 (3%)

Query: 3   VFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLL-SELGV 61
           V +EL  I++   + G ++ R+GF      LL G+  G   +  ++   E     +E+GV
Sbjct: 7   VLIELGAIILALGLLGRIAGRVGFSPIPLYLLAGLAFGHGGMLPMQASEEFTATGAEIGV 66

Query: 62  VMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLT 121
           ++LL L GLE    E      + +    +   +  + G + +++ G+G + A+   GV  
Sbjct: 67  ILLLLLLGLEYSASELVTNLKTQYPSGAVDFVLNAVPGAVAALVLGWGPVAAVALAGVTW 126

Query: 122 ATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEII 181
            +S G+   +L D+ +L  +    +L   +++D+   V L +L A+ +   +    + ++
Sbjct: 127 ISSSGVIAKVLGDLGRLGNRETPVVLGVLVIEDLAMAVYLPILTALLAGVSLAGGAVTLL 186

Query: 182 LLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGITG 241
           +    +  +L + + H  +      S+     ET+    + + L+ A LA++ Q++   G
Sbjct: 187 ISLGTVGAVLYLALRHGRLISRAVSSDSA---ETLLLVVLGLTLVVAGLAQELQVSAAVG 243

Query: 242 AYLAGLLVS--MTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSL 299
           A+L G+ +S  + EG+      ++T    LF  +F V  G+ T+   +    V AL+ + 
Sbjct: 244 AFLVGIALSGEVAEGA----SSLLTPLRDLFAAVFFVFFGLSTNPADIPPVLVPALLLAA 299

Query: 300 IAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTR-GDLAVP 358
           +  + K+    + A  A  +     + G  ++ R E +++IA  GL  G+  R G LA  
Sbjct: 300 VTALTKVATGWYAAHRAGLRGAGRWRAGGTLVARGEFSIVIA--GLAVGVEPRIGPLATA 357

Query: 359 VTMVVI 364
             ++++
Sbjct: 358 YVLILV 363


>pir||C71934 glutathione-regulated potassium-efflux system protein -
           Helicobacter pylori (strain J99)
           >gi|4154959|gb|AAD06004.1| (AE001476)
           GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYSTEM PROTEIN
           [Helicobacter pylori J99]
           Length = 416
           
 Score = 92.4 bits (226), Expect = 8e-18
 Identities = 90/391 (23%), Positives = 175/391 (44%), Gaps = 34/391 (8%)

Query: 11  LVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVMLLFLAGL 70
           L +A  FG    +L  P  +G +  G ++  +   + ++   +  + E G+V L+F+ G+
Sbjct: 13  LWLAVGFGIFLKKLDMPVIIGYICTGTVLA-AFFKINDFNL-LSDIGEFGIVFLMFMIGI 70

Query: 71  ETDVEEFKHVGLSAFIVAVMGV----FVPFLLGYLVSVLHGYGSLKALFFGGVLTATSVG 126
           E + ++ K +     +  ++ V     + FLLGY V    G   + +L  G  L+ +S  
Sbjct: 71  EFNFDKLKSIKQEVLVFGLLQVVLCALIAFLLGYFVL---GLSPIFSLVLGMGLSLSSTA 127

Query: 127 LTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIILLEVA 186
           +      D K+L T +G + +   I  D+  I +L +L  + S+       I   L+   
Sbjct: 128 IVLKFFEDSKQLSTPMGKSAVGILIFQDIAAIPMLLILTILGSKDSHVNLLILKTLISAG 187

Query: 187 IFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGITGAYLAG 246
           I  IL +L G      +L  ++   LPE      +VI+   A L+  F  +   GA++ G
Sbjct: 188 IILILLLLPGKKGANLILEQAKDTRLPEIFIGTVLVIVCSAAGLSHFFGFSMSLGAFIVG 247

Query: 247 LLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLIAVVGKI 306
           + +S +     + ++   +  +LF+ +F ++IG++ ++        F +V  L+ +V   
Sbjct: 248 MAISKSRYKINVQEEFAQL-KNLFLALFFITIGMQINVSFFMEK--FFVVIFLLILVMSF 304

Query: 307 IGCGFGALVARFKPIE-AIQVGIGMIPRMEVALII---------ANVGLKEGIL------ 350
                 AL+  F+  + AI+  + +    E + +I          N+  K+GIL      
Sbjct: 305 KTFIIYALLRFFRDAKTAIKTALSLAQIGEFSFVIFLNSGSHQLFNLQEKKGILGFLHQK 364

Query: 351 -----TRGDL-AVPVTMVVITTLITPFLLKW 375
                 + D+  + + MVV + L TPF+LK+
Sbjct: 365 NILNIAQNDIHQLLILMVVFSMLATPFILKY 395


>pir||F82595 glutathione-regulated potassium efflux system protein XF2140
           [imported] - Xylella fastidiosa (strain 9a5c)
           >gi|9107273|gb|AAF84939.1|AE004028_7 (AE004028)
           cation:proton antiporter [Xylella fastidiosa]
           Length = 572
           
 Score = 92.4 bits (226), Expect = 8e-18
 Identities = 87/387 (22%), Positives = 168/387 (42%), Gaps = 19/387 (4%)

Query: 7   LAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVMLLF 66
           +A+ L +A + G L+ RL     +G L+ G+ +GP     V        LSELGV++L+F
Sbjct: 11  IAVGLSLAFVLGALAQRLKLSPLVGYLVAGICVGPFTPGFVADQQIANQLSELGVMLLMF 70

Query: 67  LAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTATSVG 126
             GL   +E+   V   A   A++ +    LLG+ ++   G+  ++ + FG  L+  S  
Sbjct: 71  GVGLHFSLEDLLEVKAIAIPGALVQIAAATLLGWGLAWTMGWPMVQGVVFGLALSVASTV 130

Query: 127 LTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAM-----------------SS 169
           +    L + + + T+ G   +   IV+D++ ++ L LL A+                 SS
Sbjct: 131 VLLRALEERRLIDTQRGRIAVGWLIVEDLVMVLALVLLPALAQMLNGNESVAAHTPNGSS 190

Query: 170 RGKVEVEDIEIILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAY 229
            G   +  +   LL++A F  + +++G  ++   L         E  T   + I L  A+
Sbjct: 191 DGNAMLTALGWTLLKMAGFVAVMLVVGRRVIPWSLEKVAATGSRELFTLAVLGIALGVAF 250

Query: 230 -LAEKFQLAGITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLT 288
             A+ F ++   GA+ AG+++  +E S       + +    F  +F V++G+  +  +L 
Sbjct: 251 GSAKLFGVSFALGAFFAGMVLKGSETSHAAATDSLPL-RDAFAVLFFVAVGMLFNPAILI 309

Query: 289 HAGVFALVYSLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEG 348
              +  L   L   +GK                 A+ +   +    E + I+A +G++  
Sbjct: 310 EHPLQVLATFLTITIGKSAAAFLIVRAFGHPTSTALTISTSLAQIGEFSFILAGLGIQLA 369

Query: 349 ILTRGDLAVPVTMVVITTLITPFLLKW 375
           IL      + +   +++ +  PFL  W
Sbjct: 370 ILPETGRDLILAGALLSIIANPFLFTW 396


>pir||A72473 probable Na+/H+ antiporter APE2426 - Aeropyrum pernix  (strain K1)
           >gi|5106130|dbj|BAA81441.1| (AP000064) 412aa long
           hypothetical Na+/H+ antiporter [Aeropyrum pernix]
           Length = 412
           
 Score = 92.1 bits (225), Expect = 1e-17
 Identities = 86/380 (22%), Positives = 175/380 (45%), Gaps = 25/380 (6%)

Query: 1   MEVFLELAIILVIAKIFGYLSVR-----LGFPAALGQLLGGVIIGPSLLDVVEYGSEVRL 55
           +E  +E  I++++   F  L+       +G P  + +++ G ++       V+    + L
Sbjct: 50  LEFEVEYDILVIVLVAFYILAATRIAHVIGLPPGVVEIIMGAMLA---FWGVKSTEVLTL 106

Query: 56  LSELGVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALF 115
           L+ +G  +LLF+AG E D+   + +   A IVA++    P  L  L+ V  G     +L 
Sbjct: 107 LAAIGANLLLFMAGSEIDLALLRSILPQAVIVALVSALAPLALTALLHVYLGLSLTSSLV 166

Query: 116 FGGVLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEV 175
               L+ATSV LT  +L   + +R+++G   LA+A++ D+ G+++L +  A  S      
Sbjct: 167 ILASLSATSVALTYLLLSSYRLVRSRLGQLALASAMLLDLSGMIMLNIATASISPSLAFY 226

Query: 176 EDIEIILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQ 235
             I I+L  + ++ +L  L G P   E+  ++              + ++I  +L++   
Sbjct: 227 --IVILLAALLLYPLLPRLGGAPFEAEIRLIT--------------MTVIILGFLSDFVG 270

Query: 236 LAGITGAYLAGLLVSMTEGSR-KITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFA 294
           +  +  +++ G++ S T  +R ++ +K+ ++    F P F ++ G+  D  +  H    A
Sbjct: 271 VHSVLTSFILGVIASETVRTRVQLREKLESLATGFFTPFFFIASGMSIDPGIPLHYVALA 330

Query: 295 LVYSLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGD 354
           L   +   + +     F   +       ++         + V +I A+VG + G+L    
Sbjct: 331 LAGGVALALARTYTVYFYFRLTGSSRRSSLIAASSTAMLLTVTIIAASVGFQLGLLDSLM 390

Query: 355 LAVPVTMVVITTLITPFLLK 374
            +V V +VV T L +  L+K
Sbjct: 391 YSVLVWIVVGTILGSFALVK 410


>sp|P45522|KEFB_ECOLI GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYSTEM PROTEIN KEFB
           (K(+)/H(+) ANTIPORTER) (NEM-ACTIVATABLE K+/H+
           ANTIPORTER) >gi|7444645|pir||A65129
           glutathione-regulated potassium-efflux system protein
           kefB - Escherichia coli (strain K-12)
           >gi|606284|gb|AAA58147.1| (U18997) ORF_f601 [Escherichia
           coli] >gi|1789749|gb|AAC76375.1| (AE000411) K+ efflux;
           NEM-activable K+/H+ antiporter [Escherichia coli K12]
           Length = 601
           
 Score = 90.1 bits (220), Expect = 4e-17
 Identities = 83/373 (22%), Positives = 168/373 (44%), Gaps = 6/373 (1%)

Query: 4   FLELAIILVIAKIFGY-LSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVV 62
           FL   ++ + A +    L+ RLG  A LG LL G+ IGP  L  +    E+   SELGVV
Sbjct: 6   FLLAGVLFLFAAVAAVPLASRLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVV 65

Query: 63  MLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTA 122
            L+F+ GLE +  +   +  S F V    V +   L   + +L  +    A+  G  L  
Sbjct: 66  FLMFIIGLELNPSKLWQLRRSIFGVGAAQVLLSAALLAGLLMLTDFAWQAAVVGGIGLAM 125

Query: 123 TSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIIL 182
           +S  +   ++ +    R++ G    +  +  D+  I  L L+  ++       E  + + 
Sbjct: 126 SSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSAD---EHFDWMK 182

Query: 183 LEVAIFFILGILI-GHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGITG 241
           + + +   +G+LI G  L++ V        + E  T   ++++L  A   +   L+   G
Sbjct: 183 VGMKVLAFVGMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLGSALFMDALGLSMALG 242

Query: 242 AYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLIA 301
            ++AG+L++ +E   ++   I      L + +F +S+G+  ++ VL    ++ ++  ++ 
Sbjct: 243 TFIAGVLLAESEYRHELETAIDPF-KGLLLGLFFISVGMSLNLGVLYTHLLWVVISVVVL 301

Query: 302 VVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVTM 361
           V  KI+     A +   +  E +Q    +    E A ++ +    + +     +A+ +  
Sbjct: 302 VAVKILVLYLLARLYGVRSSERMQFAGVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVT 361

Query: 362 VVITTLITPFLLK 374
           V ++ + TP L+K
Sbjct: 362 VTLSMMTTPLLMK 374


>pir||C81997 probable glutathione-regulated potassium-efflux system protein
           NMA0060 [imported] - Neisseria meningitidis (group A
           strain Z2491) >gi|7378833|emb|CAB83376.1| (AL162752)
           putative transmembrane transport protein [Neisseria
           meningitidis Z2491]
           Length = 658
           
 Score = 90.1 bits (220), Expect = 4e-17
 Identities = 78/369 (21%), Positives = 164/369 (44%), Gaps = 4/369 (1%)

Query: 7   LAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVMLLF 66
           + I+L+++ I   L  +   P+ LG LL G + GP +L ++        L E+G+V L+F
Sbjct: 9   IVIVLLVSVITVILCRKFNIPSMLGYLLVGFLAGPGMLSLIPKSHATDYLGEIGIVFLMF 68

Query: 67  LAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTATSVG 126
             GLE  + + + +    F +  + V V  L    + +L G     A    G L  +S  
Sbjct: 69  SIGLEFSLPKLRAMRRLVFGLGGLQVGVTMLSVMGILMLTGVPFNWAFAVSGALAMSSTA 128

Query: 127 LTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIILLEVA 186
           + + IL +  +L    G   +   ++ D+  + ++ L+ A++  G   +    + L    
Sbjct: 129 IVSRILSEKTELGQPHGQMAMGVLLMQDIAVVPLMILIPALAGGGDGNIW-AALGLAFAK 187

Query: 187 IFFILGIL--IGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGITGAYL 244
           +   LG+L  +G  ++     +  +    E      +++ L  AYL E   L+   GA++
Sbjct: 188 MLLTLGLLFFVGSKIMSRWFRMVAKRKSSELFMINVLLVTLGVAYLTELEGLSMALGAFV 247

Query: 245 AGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLIAVVG 304
           AG+L+S TE   ++ D I      + +  F +++G++ DI+ L       L+   + +V 
Sbjct: 248 AGMLLSETEYRFQVEDDIRPF-RDILLGFFFITVGMKLDIQALIGGWRQVLMLLAMLLVL 306

Query: 305 KIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVTMVVI 364
           K +     A   +    ++++  + +    E   ++  +  +  +++          V++
Sbjct: 307 KALVVFAIAFKMKHSVGDSLKTALYLAQGGEFGFVMLAIAGQLDMVSLEWEQAATAAVLL 366

Query: 365 TTLITPFLL 373
           + +I PFLL
Sbjct: 367 SMIIAPFLL 375


>pir||B81225 glutathione-regulated potassium-efflux system protein NMB0209
           [imported] - Neisseria meningitidis (group B strain
           MD58) >gi|7225431|gb|AAF40666.1| (AE002378)
           glutathione-regulated potassium-efflux system protein
           [Neisseria meningitidis MC58]
           Length = 658
           
 Score = 89.7 bits (219), Expect = 5e-17
 Identities = 77/369 (20%), Positives = 164/369 (43%), Gaps = 4/369 (1%)

Query: 7   LAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVMLLF 66
           + I+L+++ I   L  +   P+ LG LL G + GP +L ++        L E+G+V L+F
Sbjct: 9   IVIVLLVSVITVILCRKFNIPSMLGYLLVGFLAGPGMLSLIPKSHATDYLGEIGIVFLMF 68

Query: 67  LAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTATSVG 126
             GLE  + + + +    F +  + V +  L    + +L G     A    G L  +S  
Sbjct: 69  SIGLEFSLPKLRAMRRLVFGLGGLQVGITMLSVMGILMLTGVPFNWAFAVSGALAMSSTA 128

Query: 127 LTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIILLEVA 186
           + + IL +  +L    G   +   ++ D+  + ++ L+ A++  G   +    + L    
Sbjct: 129 IVSRILSEKTELGQPHGQMAMGVLLMQDIAVVPLMILIPALAGGGDGNIW-AALGLAFAK 187

Query: 187 IFFILGIL--IGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGITGAYL 244
           +   LG+L  +G  ++     +  +    E      +++ L  AYL E   L+   GA++
Sbjct: 188 MLLTLGLLFFVGSKIMSRWFRMVAKRKSSELFMINVLLVTLGVAYLTELEGLSMALGAFV 247

Query: 245 AGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLIAVVG 304
           AG+L+S TE   ++ D I      + +  F +++G++ DI+ L       L+   + +V 
Sbjct: 248 AGMLLSETEYRFQVEDDIRPF-RDILLGFFFITVGMKLDIQALIGGWRQVLMLLAMLLVL 306

Query: 305 KIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVTMVVI 364
           K +     A   +    ++++  + +    E   ++  +  +  +++          V++
Sbjct: 307 KALVVFAIAFKMKHSVGDSLKTALYLAQGGEFGFVMLAIAGQLDMVSPEWEQAATAAVLL 366

Query: 365 TTLITPFLL 373
           + +I PFLL
Sbjct: 367 SMIIAPFLL 375


>pir||T36239 probable integral membrane efflux protein - Streptomyces coelicolor
           >gi|4582390|emb|CAB40337.1| (AL049573) putative integral
           membrane efflux protein [Streptomyces coelicolor A3(2)]
           Length = 404
           
 Score = 88.5 bits (216), Expect = 1e-16
 Identities = 89/367 (24%), Positives = 164/367 (44%), Gaps = 30/367 (8%)

Query: 23  RLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVMLLFLAGLETDVEEFKHVGL 82
           R+  P  + ++  G+++GP +L        V  L++LG+ ML+FLAG E D   F  V  
Sbjct: 27  RVRVPLVIFEISLGIVMGPDVLGWARPDDVVDTLADLGLSMLIFLAGYEID---FAAVRG 83

Query: 83  SAFIVAVMGVFVPFLLGYLVSVLHGYGSL-KALFFGGVLTATSVGLTTSILMDMKKLRTK 141
                ++    V  + G  +++L   G + +A   G  LT+T++G    +L D  +LR +
Sbjct: 84  DTLRRSLWSWPVALVAGIALALLVSGGDVFEAFVIGTALTSTTLGTVLPMLRDSGELRGR 143

Query: 142 VGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEII-----LLEVAIFFILGILIG 196
            GT I A   V +   ++ + LL++    G+   E   ++     +   A+F+ L     
Sbjct: 144 FGTVISAFGAVGEFGPVIAVALLLS----GRRPAESAALLAAFGAITTAAVFWAL----- 194

Query: 197 HPLVKEVLTLSERI--TLPETVTTFAIVIMLIFAYLAEKFQLAGITGAYLAGLLVSMT-- 252
            P       L+ER   T  +    F ++++     LAE F L  + GA+ AG+L  +   
Sbjct: 195 RPRPPWFARLTERTLHTSGQFAVRFVMLLLACMLGLAEVFGLDVLLGAFAAGVLTRLVLL 254

Query: 253 ----EGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTH-AGVFALVYSLIAVVGKII 307
                 S ++  K+  +G+   +P+F V  GIE D+  L H  G   LV   + +   + 
Sbjct: 255 RAAPASSGEVLGKVEAMGFGFLVPLFYVVTGIEFDLAALLHDPGALLLVPGFLLLFLLVH 314

Query: 308 GCGFGALVARFKPIEAIQVGIGMIPRMEVALIIA--NVGLKEGILTRGDLAVPVTMVVIT 365
           G G   L+A        +  + +     + L++A   +G+ + ++     A  V   +++
Sbjct: 315 G-GPVYLLAPRDLGRGDRAALALFTSTCLPLVVAITTIGVDQELIATDRAASLVGAAMVS 373

Query: 366 TLITPFL 372
            L+ P L
Sbjct: 374 VLVFPLL 380


>gb|AAA84962.1| (U37008) KefC [Myxococcus xanthus]
           Length = 598
           
 Score = 87.8 bits (214), Expect = 2e-16
 Identities = 89/373 (23%), Positives = 169/373 (44%), Gaps = 16/373 (4%)

Query: 4   FLELAIILVIAKIFGY-LSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVV 62
           FL+ A++ + A +    LS RLG  + LG L GG +IGP  L ++     +  ++ELGVV
Sbjct: 3   FLQQALVFLAAVVLADPLSRRLGLGSVLGYLAGGAVIGPWGLKLISDVEHIFHVAELGVV 62

Query: 63  MLLFLAGLETDVEEFKHVGLSAF-IVAVMGVFVPFLL---GYLVSVLHGYGSLKALFFGG 118
           +LL    LE        +  S F +     +F   LL   G L S+  G     A+  G 
Sbjct: 63  VLLLFVSLELQTSRLWALRRSVFGLGGAQVLFTGALLASVGLLCSLTWG----AAIVTGF 118

Query: 119 VLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDI 178
            L+ +S      +L++  +L T  G       +  D+  + +L LL  +   G      +
Sbjct: 119 GLSLSSTAFALQLLVERNRLTTPYGQLAFGILLFQDLAVVPLLALLPLLGDGGAPSPGTV 178

Query: 179 EIILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAG 238
            ++LL+     +  +L G  LV+            E  T  A+++++  A +     L+ 
Sbjct: 179 WLLLLKDVGVLLAEVLSGRYLVRPAFRAVAATHRQELFTATALLLVVATASVINAVGLSM 238

Query: 239 ITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAG--VFALV 296
              A LAG+L++ +E   ++   +      L + +F +S+G+  ++ ++      VF LV
Sbjct: 239 GLAASLAGVLLADSEYRHELEADLAPF-KGLLMGLFFISVGMTVNLSLILQKPLLVFGLV 297

Query: 297 YSLIAVVGKII-GCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDL 355
             L+A+ G ++ G G  AL  R +P  A+ + + +    E A ++ ++   + ++ R   
Sbjct: 298 LGLVALKGAVLYGLGRMAL-GRREP--ALDLAVVISQGGEFAFVLFSLATAQHVMERSLS 354

Query: 356 AVPVTMVVITTLI 368
            + V +V ++  +
Sbjct: 355 ELLVVVVGLSMAV 367


>pir||T01227 glutathione-regulated potassium-efflux system protein kefB homolog
           F6N23.15 - Arabidopsis thaliana
           >gi|3047127|gb|AAC13638.1| (AF058919) F6N23.15 gene
           product [Arabidopsis thaliana]
           >gi|7267402|emb|CAB80872.1| (AL161472) putative
           potassium/H+ antiporter [Arabidopsis thaliana]
           Length = 617
           
 Score = 87.0 bits (212), Expect = 3e-16
 Identities = 94/374 (25%), Positives = 167/374 (44%), Gaps = 39/374 (10%)

Query: 30  LGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVMLLFLAGLETDVEEFKHVGLSAFIVAV 89
           LG L  G++IGP  L ++      + ++E GVV LLF  GLE  VE    +    F +  
Sbjct: 49  LGYLAAGILIGPYGLSIIRNVHGTKAIAEFGVVFLLFNIGLELSVERLSSMKKYVFGLGS 108

Query: 90  MGVFV-PFLLGYLVSVLHGYGSLKALFFGGVLTATSVGLTTSILMDMKKLRTKVGTTILA 148
             V V   ++G +   + G     A+  G  L  +S  +   +L +  +  ++ G    +
Sbjct: 109 AQVLVTAAVIGLITHYVAGQAGPAAIVIGNGLALSSTAVVLQVLQERGESTSRHGRATFS 168

Query: 149 AAIVDDVLGIVILTLLVAM----SSRGKV------EVEDIEIILLEVAIFFIL--GILIG 196
             +  D L +V+L +L+ +    SS+G +      E   +  I   VAI  I+  G L+ 
Sbjct: 169 VLLFQD-LAVVVLLILIPLISPNSSKGGIGFQAIAEALGLAAIKAAVAITGIIAGGRLLL 227

Query: 197 HPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGITGAYLAGLLVSMTEGSR 256
            P+ K++          E  +   ++++L  + L  +  L+   GA+LAGLL++ TE S 
Sbjct: 228 RPIYKQIAENRN----AEIFSANTLLVILGTSLLTARAGLSMALGAFLAGLLLAETEFSL 283

Query: 257 KITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLIA--VVGK-----IIGC 309
           ++   I      L + +F +++G+  D ++L     F L+   +   +VGK     IIG 
Sbjct: 284 QVESDIAPY-RGLLLGLFFMTVGMSIDPKLL--LANFPLIMGTLGLLLVGKTILVVIIGK 340

Query: 310 GFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVTMVVITTLIT 369
            FG  +     I A++VG+ + P  E A +     + + I+    + + V       L+T
Sbjct: 341 LFGISI-----ISAVRVGLLLAPGGEFAFVAFGEAVNQVIIY---MMISVFCFFTMGLVT 392

Query: 370 PFL---LKWAFSKG 380
                 L W F +G
Sbjct: 393 AVFLGELDWYFFQG 406


>gb|AAD10158.1| (AC005917) putative potassium/proton antiporter [Arabidopsis
           thaliana]
           Length = 574
           
 Score = 87.0 bits (212), Expect = 3e-16
 Identities = 82/382 (21%), Positives = 164/382 (42%), Gaps = 16/382 (4%)

Query: 1   MEVFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELG 60
           + +  +L +++V A   G      G P   G LL G IIGP  L  V    +V  +++ G
Sbjct: 152 LRLISDLVVVIVSATCGGIAFACAGQPVITGYLLAGSIIGPGGLSFVSEMVQVETVAQFG 211

Query: 61  VVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVL 120
           V+ LLF  GLE    + + V   A    ++ +F+   L  + + L G    + +F G  L
Sbjct: 212 VIFLLFALGLEFSAAKLRVVRAVAIPGGLLQIFLFMCLSGITASLCGGKLTEGIFVGAFL 271

Query: 121 TATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVE-----V 175
           + +S  +    LM+   +      + L   I D  +G++   L V   + G ++      
Sbjct: 272 SMSSTAVVLKFLMERNSI------SALHGQITDCAVGLLFALLPVLGGTSGVLQGVLSMA 325

Query: 176 EDIEIILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQ 235
           + + I++  +   F+L        +K + +LS +    E     A+   L+ A+ ++K  
Sbjct: 326 KSLAILIAFLGALFVLSRTWVPWFLKLMTSLSSQTN--ELYQLAAVAFCLLVAWCSDKLG 383

Query: 236 LAGITGAYLAGLLVSMTEGSRKITDKIMTIG---YSLFIPIFLVSIGIETDIRVLTHAGV 292
           L+   G++ AG+++S T+ ++   ++  +      + F  +FL SIG+   +  L +   
Sbjct: 384 LSLELGSFAAGVMISTTDLAQHTLEQARSQVEPIRNFFAALFLASIGMLIHMHFLWNHVD 443

Query: 293 FALVYSLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTR 352
             L   L+ +V K +       V  +    A+ VG+ +    E A ++ +      ++  
Sbjct: 444 ILLAAVLLVIVIKTVVVAIVVKVFGYNNKTAVLVGMSLAQIGEFAFVLLSRASNLHLIES 503

Query: 353 GDLAVPVTMVVITTLITPFLLK 374
               + +    ++ + TP L K
Sbjct: 504 KLYLLLLGTTALSLVTTPLLFK 525


>gb|AAD32281.1|AC006533_5 (AC006533) putative Na+/H+ antiporter [Arabidopsis thaliana]
           Length = 735
           
 Score = 87.0 bits (212), Expect = 3e-16
 Identities = 76/298 (25%), Positives = 137/298 (45%), Gaps = 11/298 (3%)

Query: 57  SELGVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFF 116
           + L +V  +FL GL  D+   K   +   I+A++G+    L G  +  L   G    +  
Sbjct: 7   ANLALVYNVFLLGLGLDLRMIKIKDIKPVIIAIVGLLAALLAGAGLYYLPSNGEADKILA 66

Query: 117 GGVLTATSVGLTT-----SILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRG 171
           G +  + + G T       IL D+K LRT +G T + AA+V D+   ++    +A+ S+ 
Sbjct: 67  GCMYWSIAFGCTNFPDLARILADLKLLRTDMGHTAMCAAVVTDLCTWILFIFGMAIFSKS 126

Query: 172 KVEVEDIEIILLEVAIFFILGILIGHPLVKEVLTLS-ERITLPETVTTFAIVIMLIFAYL 230
            V  E +   L     F +L   +  P V  +   + E   + +T   + +  ++I + +
Sbjct: 127 GVRNEMLPYSLASTIAFVLLCYFVIQPGVAWIFNNTVEGGQVGDTHVWYTLAGVIICSLI 186

Query: 231 AEKFQLAGITGAYLAGLLVSMTEGSRK-ITDKIMTIGYSLFIPIFLVSIGIETDIRVLTH 289
            E   +  ITGA+L GL +      RK I +K+      + +P+F +  G+  DI  +  
Sbjct: 187 TEVCGVHSITGAFLFGLSIPHDHIIRKMIEEKLHDFLSGMLMPLFYIICGLRADIGYMNR 246

Query: 290 ---AGVFALVYSLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVG 344
               G+ A+V S  +V+ KI+   F ++  R    + + +G  M  +  +AL+I N G
Sbjct: 247 TVSVGMMAVVTS-ASVMVKILSTMFCSIFLRIPLRDGLAIGALMNTKGTMALVILNAG 303


>pir||F69201 conserved hypothetical protein MTH760 - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2621849|gb|AAB85263.1| (AE000854) Na+/H+-exchanging
           protein:Na+/H+ antiporter [Methanobacterium
           thermoautotrophicum]
           Length = 399
           
 Score = 85.4 bits (208), Expect = 1e-15
 Identities = 85/391 (21%), Positives = 176/391 (44%), Gaps = 25/391 (6%)

Query: 3   VFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLD-----VVEYGSEVRLLS 57
           V   +A+I+++  +F  +  R   P  LG L+ G++IGP  L+     +++   ++R+++
Sbjct: 4   VAFSVAVIILLGLLFNRVFTRARLPGILGMLILGILIGPHGLNLISKSIMDISPDLRVIA 63

Query: 58  ELGVVMLLFLAGLETDVEEFKHVGLSAFIVA-VMGVFVPFLLGYLVSVLHGYGSLKALFF 116
              ++++L  AG   ++E  + VG++A  ++ +  VF    +      + G   ++A   
Sbjct: 64  ---LIIILLRAGFGINLESLRKVGMTAVKMSFIPDVFEGLAVMVASHYILGLPIIEAGIL 120

Query: 117 GGVLTATSVGLTTSILMDM--KKLRTKVG--TTILAAAIVDDVLGIVILTLLVAMSSRGK 172
           G V+ A S  +    ++    +++ T  G  T IL  A VDDV+ I + ++ + +    +
Sbjct: 121 GFVIAAVSPAVIVPQMLSFIERRMGTAKGIPTIILTGASVDDVVSITLFSVFLGIYQGQQ 180

Query: 173 VEVEDIEIILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTF-----AIVIMLIF 227
           V   ++ +  + V +  + GI  G  L   ++ L  R  +  T  T      AI++  + 
Sbjct: 181 V---NLLVEAIGVPLSILTGITGGLALGLALVYLFRRFEIRNTEKTLIILGAAILLKNMG 237

Query: 228 AYLAEKFQLAGITGAYLAGLLV--SMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIR 285
             ++    +A + G  + GL++   M E   K+++K   +     I +F V +G + D+R
Sbjct: 238 DLISTYLPIAALVGVMVVGLVILERMPETGLKLSEKFNKVWIFAEILLF-VLVGAQVDVR 296

Query: 286 VLTHAGVFALVYSLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGL 345
           ++ H G+  L      ++ + IG             E +      IP+  V   I  + L
Sbjct: 297 LIFHVGLLGLAVITAGLMVRSIGVLLSLKGTDLNLKEKVFCISAYIPKATVQAAIGAIPL 356

Query: 346 KEGILT-RGDLAVPVTMVVITTLITPFLLKW 375
             G+      LA+ V  ++ T  +    +KW
Sbjct: 357 AAGVAAGETILAMAVLAILFTAPLGSLAVKW 387


>pir||T35102 probable transmembrane transport protein - Streptomyces coelicolor
           >gi|2995290|emb|CAA18319.1| (AL022268) putative
           transmembrane transport protein [Streptomyces coelicolor
           A3(2)]
           Length = 411
           
 Score = 84.7 bits (206), Expect = 2e-15
 Identities = 78/366 (21%), Positives = 165/366 (44%), Gaps = 11/366 (3%)

Query: 3   VFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPS-LLDVVEYGSEVRLLSELGV 61
           + +E   I++   + G  + R         LL G+  G   LL +      V   +E+GV
Sbjct: 6   LLIEFGSIILGLGLLGRFAGRYRLSPIPLYLLAGLAFGEGGLLPLGASEEFVATGAEIGV 65

Query: 62  VMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLT 121
           ++LL + GLE    +      S +   ++   +  + G + ++L G+G + A+   GV  
Sbjct: 66  ILLLLMLGLEYTASDLVTNLKSHYPAGLVDCALNAVPGAVAALLMGWGPVAAVVLAGVTW 125

Query: 122 ATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEII 181
            +S G+   +L D+ ++  +    IL+  +++D+   V L ++ A+ +   +    I + 
Sbjct: 126 ISSSGVIAKVLGDLGRVGNRETPVILSVLVLEDLAMAVYLPIVTALVAGAGLMTGSITLA 185

Query: 182 LLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGITG 241
           +   A   +L + + +  +      S+    PE +    + + ++ A +A++ Q++   G
Sbjct: 186 VALAAAGLVLFVAVRYGRLISRFVSSDD---PEKLLLVVLGLTILVAGVAQQLQVSAAVG 242

Query: 242 AYLAGLLVS--MTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSL 299
           A+L G+ +S  + EG+  +   +      LF  +F V  G+ TD   +    + AL  +L
Sbjct: 243 AFLVGIALSGEVAEGAHTLLSPLR----DLFAAVFFVFFGLHTDPASIPPVLLPALALAL 298

Query: 300 IAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGI-LTRGDLAVP 358
           +  V KI    + A  A        + G  ++ R E +++IA + +  GI  + G LA  
Sbjct: 299 LTAVTKIATGYWAARRAGISVKGRWRAGGALVARGEFSIVIAGLAVSAGIEPSLGPLATA 358

Query: 359 VTMVVI 364
             ++++
Sbjct: 359 YVLILV 364


>gb|AAD30610.1|AC007153_2 (AC007153) similar to Na/H antiporter proteins [Arabidopsis
           thaliana]
           Length = 855
           
 Score = 84.7 bits (206), Expect = 2e-15
 Identities = 88/377 (23%), Positives = 162/377 (42%), Gaps = 34/377 (9%)

Query: 15  KIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEY----------GSEVRLLSELGVVML 64
           ++  YL+  L  P  + Q+L G++  PS+L    +             +   + L +V  
Sbjct: 66  RVLYYLTRPLYLPPFVAQILCGLLFSPSVLGNTRFIIAHVFPYRFTMVLETFANLALVYN 125

Query: 65  LFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTATS 124
           +FL GL  D+   +   L   I+A  G+ V   +G  +  L G G    +  G V  + +
Sbjct: 126 IFLLGLGMDLRMVRITELKPVIIAFTGLLVALPVGAFLYYLPGNGHPDKIISGCVFWSVA 185

Query: 125 VGLTT-----SILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIE 179
           +  T       IL D+K LR+ +G T + AAIV D+   V+L    A  S+     + + 
Sbjct: 186 LACTNFPDLARILADLKLLRSDMGRTAMCAAIVTDLCTWVLLVFGFASFSKSGTWNKMMP 245

Query: 180 IILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGI 239
            +++  AIF +L I +  P +  +          +TV    +V+      + +   +  I
Sbjct: 246 FVIITTAIFVLLCIFVIRPGIAWIFA--------KTVKAGGVVLC---GLITDACGVHSI 294

Query: 240 TGAYLAGLLVSMTEGSRK-ITDKIMTIGYSLFIPIFLVSIGIETDIR-VLTHAGVFALVY 297
           TGA+L GL +      R  I +K+      + +P+F +  G+  DI  +L     F +V 
Sbjct: 295 TGAFLFGLSIPHDHIIRNMIEEKLHDFLSGILMPLFYIICGLRADIGFMLQFTDKFMMVV 354

Query: 298 SLI-AVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVG-----LKEGILT 351
            +  + + KI+     +L       +A  +G  M  +  ++L++ N G     L   + T
Sbjct: 355 VICSSFLVKIVTTVITSLFMHIPMRDAFAIGALMNTKGTLSLVVLNAGRDTKALDSPMYT 414

Query: 352 RGDLAVPVTMVVITTLI 368
              +A+ V  +V+  L+
Sbjct: 415 HMTIALLVMSLVVEPLL 431


>pir||F70591 probable kefB protein - Mycobacterium tuberculosis (strain H37RV)
           >gi|2072703|emb|CAB08337.1| (Z95121) kefB [Mycobacterium
           tuberculosis]
           Length = 385
           
 Score = 83.9 bits (204), Expect = 3e-15
 Identities = 93/386 (24%), Positives = 162/386 (41%), Gaps = 33/386 (8%)

Query: 3   VFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPS-LLDVVEYGSEVRLLSELGV 61
           +  EL ++L +  + G ++ R         LL G+ +G   +L V   G  +   + +GV
Sbjct: 7   LLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGV 66

Query: 62  VMLLFLAGLETDVEEF----KHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFG 117
           V+LL   GLE    EF    +H   SA +  V+      + G+L+    G   +  L   
Sbjct: 67  VLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLL----GLDGVAILGLA 122

Query: 118 GVLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGK-VEVE 176
           GV   +S G+   +L D+++L  +    +L+  +++D      L L   +++ G  +E  
Sbjct: 123 GVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEA- 181

Query: 177 DIEIILLEVAIFFILGILI-----GHPLVKEVLTLSERITLP--ETVTTFAIVIMLIFAY 229
              ++ + VAI  +LG        GH        +   +T P  E +    + I LI A 
Sbjct: 182 ---VVGMTVAIAALLGAFAASYRWGH-------HVGRLVTHPDSEQLLLRVLGITLIVAA 231

Query: 230 LAEKFQLAGITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTH 289
           +AE    +   GA+L GL ++     R     ++T    LF  IF + IG+  D   L  
Sbjct: 232 VAESLHASAAVGAFLVGLTLTGETADR--ARMVLTPLRDLFATIFFLGIGLSVDPGKLVS 289

Query: 290 AGVFALVYSLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGI 349
               AL  + +    K+    F A          ++ G  ++ R E +LII  +GL  G 
Sbjct: 290 MLPVALALAAVTAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLII--IGL-AGA 346

Query: 350 LTRGDLAVPVTMVVITTLITPFLLKW 375
              G  A+    V +  ++ P L ++
Sbjct: 347 SIPGVAALATAYVFVMAIVGPILARY 372


>emb|CAB44437.1| (AJ242913) glutathione-gated K efflux system [Klebsiella aerogenes]
           Length = 621
           
 Score = 81.5 bits (198), Expect = 1e-14
 Identities = 68/277 (24%), Positives = 124/277 (44%), Gaps = 9/277 (3%)

Query: 8   AIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVMLLFL 67
           A+I+ IA + G  SV       LG L+ G IIGP  L +V     +   +E+GVV++L  
Sbjct: 17  ALIVPIASVLGLGSV-------LGYLIAGCIIGPWALRLVNDAEAILHFAEIGVVLMLVA 69

Query: 68  AGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTATSVGL 127
            GLE D +    +  S F    + +    +L  L  +L G     A   G  L  +S  +
Sbjct: 70  MGLELDPQRLWKLRASVFDGGALQMVACGVLIGLFCMLLGLRWQVAELIGMTLALSSTAI 129

Query: 128 TTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLL-VAMSSRGKVEVEDIEIILLEVA 186
               + +     +++G +  A  +  D+  I ++ ++ +  +S G   +    +  L+VA
Sbjct: 130 AMQAMNERNLTVSQMGRSAFAVLLFQDIAAIPLVAMIPLLAASGGATSLMAFALSALKVA 189

Query: 187 IFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGITGAYLAG 246
               L +++G  L + +L    R  L E  +  A         L E+  L+   GA+LAG
Sbjct: 190 AALALVVVLGRYLTRPLLRFVARSGLREVFSAVACSWSSALGLLLEEVGLSMAMGAFLAG 249

Query: 247 LLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETD 283
           +L++ +E    + + I  +   L + +F + +G+  D
Sbjct: 250 VLLASSEYRHALENDIEPV-KGLLLGLFFIGVGMSID 285


>emb|CAB76285.1| (AL158057) putative transmembrane transport protein. [Streptomyces
           coelicolor A3(2)]
           Length = 446
           
 Score = 81.5 bits (198), Expect = 1e-14
 Identities = 85/354 (24%), Positives = 154/354 (43%), Gaps = 13/354 (3%)

Query: 2   EVFLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSL--LDVVEYGSEVRLLSEL 59
           +  L +    V A     L  R+G P     +L G+++GP      +VE   +  +LS L
Sbjct: 5   DTLLAMGGAFVAAAFLARLGGRIGLPTIPLFMLAGILLGPHTPGFVLVEDAHDFEMLSAL 64

Query: 60  GVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGV 119
           G+V+LLF  GLE  +++ +  G        + + +    G     + G+G  +AL   GV
Sbjct: 65  GLVLLLFYLGLEFHLDDLRSGGKRLLTAGGIYLLLNVGAGLGFGFVLGWGVREALVLAGV 124

Query: 120 LTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIE 179
           L  +S  + T IL+D+ ++       IL   +V+D+   + L  L  + S G   V D  
Sbjct: 125 LGISSSAIVTKILIDLGRIGRPETRLILGVIVVEDIFLALYLAALQPVIS-GAHGVADTA 183

Query: 180 IILLEVAIFFIL---GILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQL 236
           +   +   F ++       G  LV  ++   +   L  +    A+++    A ++E   +
Sbjct: 184 LQAGKAFGFLLVLAAAARYGTRLVGRLIHTRDNELLVISFLGAAVLV----AGVSEVLGV 239

Query: 237 AGITGAYLAGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTH-AGVFAL 295
           A   GA++ GL+++ T    +I + +  +    F  IF  + G+  D   L   AG  A 
Sbjct: 240 ADAIGAFMVGLILAGTPSGPRIRELVHPL-RDAFAAIFFFAFGLAIDPGDLASVAGPVAA 298

Query: 296 VYSLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGI 349
             +L  V+  + G    A V  +    A ++   ++ R E ALI+A +    G+
Sbjct: 299 AAALTVVMNIVAGLCV-ARVYHYGSEPAAEIATTLVARGEFALILAAMAAGAGL 351


>emb|CAC12310.1| (AL445066) Na+/H+ antiporter related protein [Thermoplasma
           acidophilum]
           Length = 381
           
 Score = 81.1 bits (197), Expect = 2e-14
 Identities = 77/369 (20%), Positives = 160/369 (42%), Gaps = 20/369 (5%)

Query: 16  IFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVMLLFLAGLETDVE 75
           + G L  R   P  +  ++ G+I+G  +L ++     +  +  + +  ++   G+E + E
Sbjct: 2   LLGVLLDRFRIPEVVAYIVSGIIVGAGVLRIIMPSQTISDIESISLFFIILSIGVEANTE 61

Query: 76  EFKHVGLSAFIVAVMGVFVPFLLGYLV-SVLHGYGSLKALFFGGVLTATSVGLTTSILMD 134
                   + +  + G   P +LG  V + +  +G + +      ++  S+ + + +LM 
Sbjct: 62  YIYGNLKRSILFTISGFIFPMILGLAVLNFISPFGFIPSFVVSLSVSVPSISIISVLLMK 121

Query: 135 MKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIILLEVAIFFILGIL 194
              L+   G  IL++ ++ D++  ++L+   A +      +E +  ++L   +  I  I+
Sbjct: 122 YDLLKVNGGRLILSSVVLTDIVAFIMLS---ATTENVYHVLESLGFVILFFVVIAIFDII 178

Query: 195 IGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEK--FQLAGIT---GAYLAGLLV 249
           I    +  +  + +R    +T   + +  M+I A L     F++ GIT   G++ AG+L+
Sbjct: 179 IRRRAIGIMAWIEKREE--KTNMEYILFSMIIIAGLLVSIIFEVIGITYVLGSFFAGILI 236

Query: 250 SMTEGSRK----ITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLIAVVGK 305
                  K    + + +  I  S FIP+F    GI      L    +F     +I V G 
Sbjct: 237 HEASVGEKYHRILVNTLKRINDSFFIPLFFSIAGISVVFPHLDTFIIFLPALIVIIVSGT 296

Query: 306 IIGCGFGALVAR-FKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVT-MVV 363
           ++         R   P+  + V  G   R  V +IIA +    GI+T    ++ +   V+
Sbjct: 297 LLNYALSKRFIRSITPLTTMSVLGG---RGAVGVIIAAIAYDTGIITSIQYSLAILGTVL 353

Query: 364 ITTLITPFL 372
           I+ +ITP +
Sbjct: 354 ISLIITPLI 362


>dbj|BAB10612.1| (AB005243) Na+/H+ antiporter-like protein [Arabidopsis thaliana]
           Length = 800
           
 Score = 80.4 bits (195), Expect = 3e-14
 Identities = 93/415 (22%), Positives = 179/415 (42%), Gaps = 60/415 (14%)

Query: 5   LELAIILV-IAKIFGYLSVR-LGFPAALGQLLGGVIIGPSLLDVVEYGSE---------- 52
           LEL IIL+ +  +  ++ +R +G P  +  +L G+I+GP LLD++EY S+          
Sbjct: 52  LELQIILIFVCIVLSHMFLRRIGIPRFVSNILAGLILGPQLLDLLEYSSDRLSLDIPGNV 111

Query: 53  -VRLLSELGVVMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGY------LVSVL 105
            +  ++ LG+VM  FL G++T+      +G    ++AV   FV  + G       L  V 
Sbjct: 112 ALEGVARLGLVMFTFLMGVKTNKRAVYQIGKRPIVIAVSSFFVTMISGLAFRNFRLDKVD 171

Query: 106 HGYGSLKAL-----FFGGVLTATSVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVI 160
             Y  L+           +   T + + T ++ ++K   +++G   ++ A V D LG + 
Sbjct: 172 PLYMPLRLAPTERSVIVSIQAVTLLPVITHLVYELKMSNSELGRIAISTAAVSDFLGFLT 231

Query: 161 LTLLVAMS-----SRGKVEVEDIEIILLEVAIFFILGILIGHPLVKEVLTLS-ERITLPE 214
           L  +  +      S G    + + +I+L + I FI       P+ + ++ ++ E   +P+
Sbjct: 232 LVCISYVGTYRYVSPGIANRDIVALIILVLVILFIF-----KPMAQRIVDMTPEGKPVPK 286

Query: 215 TVTTFAIVIMLIFAYLAEKFQLAGITGAYLAGLLVSMTEG---SRKITDKIMTIGYSLFI 271
                 I+  +  +     F    I GA L GL  ++ +G      +  +  ++  ++F 
Sbjct: 287 VYLYVTILTAIAASIYLSVFNQMYILGALLVGL--AIPDGPPLGSALEARFESLVTNIFF 344

Query: 272 PIFLVSIGIETDIRVLTHAGVFALVYSLIAVVGKIIGCGFGALV---ARFKPI------- 321
           PI +  + ++ D        V   +YS   +   I+  G   +V   A F P        
Sbjct: 345 PISIAVMAMKAD--------VVRALYSFDDISFNILLLGLTVVVKWTASFVPCLIFCELP 396

Query: 322 --EAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVTMVVITTLITPFLLK 374
             E++ +   M  +  V L   +V L+   L+R    V +  V++   I P ++K
Sbjct: 397 TRESVIIATIMNYKGFVDLCFFDVALRRRNLSRATYTVMIIYVLLNAGILPTIIK 451


>gi|11498844 Na+/H+ antiporter (napA-2) [Archaeoglobus fulgidus]
           >gi|7483893|pir||D69405 Na+/H+ antiporter (napA-2)
           homolog - Archaeoglobus fulgidus
           >gi|2649335|gb|AAB89998.1| (AE001018) Na+/H+ antiporter
           (napA-2) [Archaeoglobus fulgidus]
           Length = 338
           
 Score = 78.8 bits (191), Expect = 1e-13
 Identities = 85/371 (22%), Positives = 159/371 (41%), Gaps = 38/371 (10%)

Query: 5   LELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVML 64
           +ELA+I+  A I   +S  L        +L G+ +G +   +    SEV  L +LG+V L
Sbjct: 1   MELAVIVFAAAIAAIISRMLRITPIPAYILVGMALGKAGWHL----SEVEFLGKLGIVFL 56

Query: 65  LFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTATS 124
           LF  GL+      K           +     FL   ++  L G+    A      +  +S
Sbjct: 57  LFYVGLKIPPSTIKKTWQRTLKSGTIDFLFNFLPPLVLLYLIGFDLRDAFILASAIYISS 116

Query: 125 VGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIILLE 184
             +   +L+D +KL       ++   + +D++ + +L L  A         E + ++ L 
Sbjct: 117 SAINLKMLVDDRKLVFTFAEVVVLLMVFEDIVLVALLFLFSAS--------EPLTLLYLA 168

Query: 185 VAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAGITGAYL 244
           +     L +    P ++++++  + +     + TF+I  + +F  LAEKF+++    A L
Sbjct: 169 LIALTALALYAISPQIEKLMSREDEVPY---LLTFSIPSISLF--LAEKFRISEALMAIL 223

Query: 245 AGLLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVLTHAGVFALVYSLIAVVG 304
            G+ +     +R   DK++     +F+ +F V  G   D+    H    +L+   +AV+G
Sbjct: 224 FGVAL-----NRLRIDKMLVPFKEVFLAVFFVFFGTMVDL----HFSYLSLLLIAVAVIG 274

Query: 305 KIIGCGFGALVARF--KPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAVPVTMV 362
           K+ G  F   +ARF     +A++V    + R E  +I          L   + A  +  V
Sbjct: 275 KLAGAYF---IARFTTSKSDAVEVFKYTLARGEFTVIFP-------ALFAPEFATTLAAV 324

Query: 363 VITTLITPFLL 373
           V+ T I   L+
Sbjct: 325 VLFTSIAGSLI 335


>pir||JC5342 Na+/H+ antiporter cdu2 - Clostridium difficile
           >gi|1770129|emb|CAA63558.1| (X92982) cdu2 [Clostridium
           difficile] >gi|1770130|emb|CAA63559.1| (X92982) cdu2
           [Clostridium difficile]
           Length = 313
           
 Score = 75.7 bits (183), Expect = 8e-13
 Identities = 72/313 (23%), Positives = 149/313 (47%), Gaps = 37/313 (11%)

Query: 7   LAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLD-----VVEYGSEVRLLSELGV 61
           LA+I ++    G +  R+  P  LG LL G+I+GP +L+     +++  S++R   ++ +
Sbjct: 5   LALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNLIDNSILDISSDLR---KIAL 61

Query: 62  VMLLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPF---LLGYLVSV--LHGYGSLKALFF 116
           +++L  AGL  D+ + K VG      AV+  F+P    ++G +V    L G   L+A   
Sbjct: 62  IIILTRAGLSLDINDLKKVGRP----AVLMCFIPATFEIIGMIVLAPKLLGVSILEAAVM 117

Query: 117 GGVLTATSVGLTTSILMDMKK----LRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGK 172
           G V+ A S  +    ++ + +        +   +LA   +DD+  IV+ T+   ++    
Sbjct: 118 GAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDIFVIVMFTVFTGLAQGNS 177

Query: 173 VEVEDIEIILLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAE 232
           +      I  L++ +  ILG++ G  +   +    +++ + ++     +++ + F  ++ 
Sbjct: 178 ISA----ISFLQIPVSIILGVIAGAVIGICLAVFFKKVHMRDSAKG-VLLLSISFLMISL 232

Query: 233 KFQLAGITGAYLAGLLVSMTEG-----SRKITDKIMTIGYS-LFIP---IFLVSIGIETD 283
           +  L GI     +GLL  M+ G       ++  + ++I YS L++    +  V +G   D
Sbjct: 233 ETALEGIVP--FSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVGAEILLFVLVGATVD 290

Query: 284 IRVLTHAGVFALV 296
           I     AG+ A++
Sbjct: 291 ISYAFKAGIGAVI 303


>pir||H81265 probable transmembrane transport protein Cj1684c [imported] -
           Campylobacter jejuni (strain NCTC 11168)
           >gi|6969099|emb|CAB73670.1| (AL139079) putative
           transmembrane transport protein [Campylobacter jejuni]
           Length = 391
           
 Score = 75.7 bits (183), Expect = 8e-13
 Identities = 78/316 (24%), Positives = 148/316 (46%), Gaps = 20/316 (6%)

Query: 5   LELAIILVIAKIFG-YLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVM 63
           L++ I++ +  +F  +++  L  P +  +++ G II       +       LL+ +G   
Sbjct: 14  LKILIVIALCLLFSPHIAKILRLPLSATEIILGAIIAH--FGFIGKSENFALLANVGFYY 71

Query: 64  LLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTAT 123
           L+F+AG+E ++  F ++      +A    F  FLL  L S +     L +L F  ++   
Sbjct: 72  LMFIAGMEVNLRAFFNMDKE---IAKKSFFYIFLLYALSSFIVWIFGL-SLVFVIIIPVM 127

Query: 124 SVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIIL- 182
           SVGL + +  D  K    +   ++ A + + V+ IV+LT+  A    G   ++  + IL 
Sbjct: 128 SVGLLSLLFKDFGKECYWLNIAMIVATLAE-VISIVLLTIAGAFLREGTGIIDVAQSILY 186

Query: 183 ------LEVAIFFILGILIG-HPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQ 235
                 L +  F +LG+L   +P +K VL   E     +     AI I++I A +  K +
Sbjct: 187 LNIFLGLCLLGFKMLGVLFWWYPQLKVVLMPWEDKNEKDIRFCMAIFILIIVAMVITKLE 246

Query: 236 LAGITGAYLAG-LLVSMTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIR-VLTHAGVF 293
           +  + G+++AG  + +  +  + +  K+ T G+   IPIF + IG   D++ +L +  V 
Sbjct: 247 I--VLGSFIAGSFIATFFDHKKDLEHKLSTFGHGFLIPIFFIHIGSTFDLKMILDYKIVL 304

Query: 294 ALVYSLIAVVGKIIGC 309
                +  +VG  I C
Sbjct: 305 QAFLLMFVMVGLRILC 320


>pir||H71848 probable na+/h+ antiporter - Helicobacter pylori (strain J99)
           >gi|4155698|gb|AAD06681.1| (AE001538) putative NA+/H+
           ANTIPORTER [Helicobacter pylori J99]
           Length = 383
           
 Score = 74.9 bits (181), Expect = 1e-12
 Identities = 62/294 (21%), Positives = 141/294 (47%), Gaps = 21/294 (7%)

Query: 4   FLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVM 63
           F   A+I+++  I  Y+S     P  + ++L G +   + +  +E      ++SE+G + 
Sbjct: 5   FFTFALIMLLIVIAPYVSRISRLPITVVEILFGSV--GAYVGFIEPTKGFEIMSEIGFLF 62

Query: 64  LLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTAT 123
           L+FL GLE ++  FK +G+S     +  +F   L+ Y +S +  +       F  +    
Sbjct: 63  LMFLCGLEVEIYLFKKLGVS----LLKRIFAYLLILYTLSFILTFSLNLEPIFMVIFPII 118

Query: 124 SVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIIL- 182
           S+G+  +++ D +K    +   +L   ++ ++L I  L ++  + S G      +++I  
Sbjct: 119 SLGMIMTLVKDYRKEILWL-DLVLKVGVIGELLSIFGLVVVDGVYSHGL----GVDLIKD 173

Query: 183 LEVAIFFILGILIGHPLVKEVLTLSERITL---PETV-----TTFAIVIMLIFAYLAEKF 234
           L + I F++ I++   + K +      + L   P++        F++++      +    
Sbjct: 174 LGILIVFLILIIVAFQIFKTLFWWFPHLKLFVMPKSSQFNQDVRFSLMLFFSLVAIVVWL 233

Query: 235 QLAGITGAYLAGLLVS-MTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVL 287
           ++  + GA+LAGL+VS       ++  K+  +G+  F+P+F + +G   D++++
Sbjct: 234 KIEMVLGAFLAGLVVSTFFPHKSELIHKLNDVGFGFFVPLFFIHVGSTLDLKLV 287


>gb|AAK43070.1| Na(+)/H(+) antiporter, putative [Sulfolobus solfataricus]
           Length = 599
           
 Score = 73.7 bits (178), Expect = 3e-12
 Identities = 86/375 (22%), Positives = 164/375 (42%), Gaps = 29/375 (7%)

Query: 7   LAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVMLLF 66
           L+++L+   +  ++  RL     +  LLGG +I  +        S   +L+ L + +L F
Sbjct: 7   LSLMLLFTLLLAFILTRLKVSPVIAYLLGG-LISFNYFHFDFNSSYFEILNFLALNLLAF 65

Query: 67  LAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTATSVG 126
             G   D+   K +   A  +A+  + +  L+ Y + +   +  L A  F   L   S+ 
Sbjct: 66  EIGTSFDISRAKELFRRAMGIALTELILIVLISYFIGLYLLHLDLFASLF---LVMASID 122

Query: 127 LTTSILMDM--KKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIILLE 184
            +TSIL  +   K+       ++A A V+D+    + ++ +A++  G   V  I  ++LE
Sbjct: 123 TSTSILYKIIGNKVDKNDRDLLVAVASVEDIEVFFLYSIAIALN--GSFNVFRISFVILE 180

Query: 185 VAIF------FILGILIGHPLVKEVLTLSERITLPETVTTFAIVIMLIFAYLAEKFQLAG 238
           V I       F    L G  + K      E I +        IV++ +F Y+++  Q+  
Sbjct: 181 VFIASLIIYAFAKYFLTGLSIFKFTSFEDESILI-----LVPIVLVFVFEYISQVTQVPA 235

Query: 239 ITGAYLAGLLVSMTEGSRKITDKIMTI-GYSLFIPIFLVSIGIETDIRVLTHAGVFALVY 297
                LAG+  S   GS K+      I  +SL    F +S+G  + +++      F L+ 
Sbjct: 236 TLTMILAGIAFSSISGSEKVLRYTGPIREFSLI--FFFLSVG--SYLKITAGISTFVLI- 290

Query: 298 SLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKEGILTRGDLAV 357
           S I +  K       + V+    ++A   G+ M+P  E  +I++   L++GI    D+A+
Sbjct: 291 SFIILAIKYFSFSTASWVSGTTLVKAFTNGLYMLPLSEFGIIVSLQALQQGI----DIAI 346

Query: 358 PVTMVVITTLITPFL 372
              + V+  L++  +
Sbjct: 347 VYYISVVVVLVSSII 361


>sp|P52071|YPH1_METEX HYPOTHETICAL PROTEIN IN PHAC 3'REGION (ORF1)
           >gi|551902|gb|AAA72331.1| (L07893) [phaC] gene products
           [Methylobacterium extorquens]
           Length = 276
           
 Score = 73.4 bits (177), Expect = 4e-12
 Identities = 69/264 (26%), Positives = 125/264 (47%), Gaps = 18/264 (6%)

Query: 7   LAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVMLLF 66
           +A+ LV A I G L+ R+  P  +G L+ G+ IGP     V   +    L+ELGV++L+F
Sbjct: 11  IALGLVCAFIGGMLAQRMRLPPLVGYLVAGIAIGPFTPGFVGDPALASQLAELGVILLMF 70

Query: 67  LAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTATSVG 126
             GL   + +   V   A   A++ + V   +G  ++   G+G+   L FG  L+  S  
Sbjct: 71  GVGLHFSIGDLLAVRTIALPGAIVQITVATAMGAGLAWGFGWGAGAGLVFGLALSVASTV 130

Query: 127 LTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMS-SRGKVEVE--------- 176
           +    L     L +  G   +   IV+D+  +V L LL A++ S G   ++         
Sbjct: 131 VLLRALEGQGLLDSDKGRIAVGWLIVEDLAMVVALVLLPALAPSLGGEAMQAAGHHGPPE 190

Query: 177 -----DIEIILLEVAIFFILGILIGHPLVKEVLTLSERITLPE--TVTTFAIVIMLIFAY 229
                 + + L +V +F  + ++ G  L+  +L L+ R    E  T+   A  + + FA 
Sbjct: 191 HGLWVTLGLTLAKVGVFVAVMLVGGRRLIPYLLGLAARTGSRELFTLAVLASAVGIAFA- 249

Query: 230 LAEKFQLAGITGAYLAGLLVSMTE 253
            +E F ++   GA+ AG++++ ++
Sbjct: 250 SSELFGVSFALGAFFAGMVLAESD 273


>pir||G64667 NA+/H+ antiporter - Helicobacter pylori (strain 26695)
           >gi|2314343|gb|AAD08229.1| (AE000624) NA+/H+ antiporter
           (napA) [Helicobacter pylori 26695]
           Length = 383
           
 Score = 73.4 bits (177), Expect = 4e-12
 Identities = 61/294 (20%), Positives = 141/294 (47%), Gaps = 21/294 (7%)

Query: 4   FLELAIILVIAKIFGYLSVRLGFPAALGQLLGGVIIGPSLLDVVEYGSEVRLLSELGVVM 63
           F   A+I+++  +  Y+S     P  + ++L G +   + +  +E      ++SE+G + 
Sbjct: 5   FFTFALIMLLIVMAPYMSRISRLPITVVEILFGSV--GAYVGFIEPTKGFEIMSEIGFLF 62

Query: 64  LLFLAGLETDVEEFKHVGLSAFIVAVMGVFVPFLLGYLVSVLHGYGSLKALFFGGVLTAT 123
           L+FL GLE ++  FK +G+S     +  +F   L+ Y +S +  +       F  +    
Sbjct: 63  LMFLCGLEVEIYLFKKLGVS----LLKRIFAYLLILYTLSFILTFSLNLEPIFMVIFPII 118

Query: 124 SVGLTTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVEDIEIIL- 182
           S+G+  +++ D +K    +   +L   ++ ++L I  L ++  + S G      +++I  
Sbjct: 119 SLGMIMTLVKDYRKEILWL-DLVLKVGVIGELLSIFGLVVVDGVYSHGL----GMDLIKD 173

Query: 183 LEVAIFFILGILIGHPLVKEVLTLSERITL---PETV-----TTFAIVIMLIFAYLAEKF 234
           L + I F++ I++   + K +      + L   P++        F++++      +    
Sbjct: 174 LGILIVFLILIIVAFQIFKTLFWWFPHLKLFVMPKSSQFNQDVRFSLMLFFSLVAIVVWL 233

Query: 235 QLAGITGAYLAGLLVS-MTEGSRKITDKIMTIGYSLFIPIFLVSIGIETDIRVL 287
           ++  + GA+LAGL+VS       ++  K+  +G+  F+P+F + +G   D++++
Sbjct: 234 KIEMVLGAFLAGLVVSTFFPHKSELIHKLNDVGFGFFVPLFFIHVGSTLDLKLV 287


>pir||T51790 hypothetical protein F28D10_120 - Arabidopsis thaliana
           >gi|9798396|emb|CAC03543.1| (AL391254) putative protein
           [Arabidopsis thaliana]
           Length = 731
           
 Score = 73.4 bits (177), Expect = 4e-12
 Identities = 81/387 (20%), Positives = 167/387 (42%), Gaps = 44/387 (11%)

Query: 24  LGFPAALGQLLGGVIIGPSLLDVVEYGS-------------EVRLLSELGVVMLLFLAGL 70
           +G       ++ G+++GP L DV+E  S              +R +S  G +M  FL  +
Sbjct: 9   IGISQIASYMIAGIVLGPQLFDVLEKSSGKLSVDPALDGIAALRCISVFGTLMFTFLMTV 68

Query: 71  ETDVEEFKHVGLSAFIVAVMGVFVP-FLLGY-----------LVSVLHGYGSLKALFFGG 118
            T      H G    ++ ++  F P F LG+            + +    G   A+    
Sbjct: 69  RTSRRVAFHSGKLPVVIGIVSFFAPLFGLGFQNFFSDNIDPHYMPLTKALGERTAI---- 124

Query: 119 VLTATSVGL--TTSILMDMKKLRTKVGTTILAAAIVDDVLGIVILTLLVAMSSRGKVEVE 176
           V+T +S+ L  TT IL+++K + +++G   L+A +++D+LG  I +++VA      + V 
Sbjct: 125 VITQSSILLPSTTYILLELKIINSELGRLALSACVINDILG--IFSMIVASIQATYIHVS 182

Query: 177 DIEII--LLEVAIFFILGILIGHPLVKEVLTLSERITLPETVTTFAIVI-MLIFAYLAEK 233
                   + V IFF++  L+  P+V+ V+  +      E +   A++I  L  A     
Sbjct: 183 HATAYRDTVAVIIFFLVVFLVFKPMVQWVIDRTPEDKPVEDMYIHAVIITALASAAYFVF 242

Query: 234 FQLAGITGAYLAGLLVSMTEG---SRKITDKIMTIGYSLFIPIFLVSIGIETD-IRVLTH 289
           F +  I G  + G+++   EG      +  K   +  ++F+PI +    +  D  R+L+ 
Sbjct: 243 FNMKYILGPLMIGIII--PEGPPLGSALEAKFERLTMNVFLPISITFSAMRCDGARILSQ 300

Query: 290 AG--VFALVYSLIAVVGKIIGCGFGALVARFKPIEAIQVGIGMIPRMEVALIIANVGLKE 347
                F +  + + +V K++ C    L  +    E++ V   +  +     ++    L +
Sbjct: 301 FNDIFFNIFLTFLILVIKLVACLAPCLYYKLPLSESLAVSFILSYKSFADFVLYEAVLDD 360

Query: 348 GILTRGDLAVPVTMVVITTLITPFLLK 374
             +++   +  +   ++   I P +L+
Sbjct: 361 TYISQATYSFLILYSLLNAGIVPTVLR 387


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.329    0.148    0.408 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 118424179
Number of Sequences: 2977
Number of extensions: 4648371
Number of successful extensions: 17212
Number of sequences better than 1.0e-10: 83
Number of HSP's better than  0.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 65
Number of HSP's that attempted gapping in prelim test: 16963
Number of HSP's gapped (non-prelim): 91
length of query: 380
length of database: 189,106,746
effective HSP length: 55
effective length of query: 325
effective length of database: 156,189,961
effective search space: 50761737325
effective search space used: 50761737325
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.7 bits)
S2: 166 (69.1 bits)