BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1255 (valS) DE:valyl-tRNA synthetase (valS)
(891 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||G75014 valyl-tRNA synthetase (vals) PAB1255 - Pyrococcus ab... 1877 0.0
pir||D71457 valine--tRNA ligase (EC 6.1.1.9) - Pyrococcus horiko... 1797 0.0
sp|Q58413|SYV_METJA VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 867 0.0
sp|O26861|SYV_METTH VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 813 0.0
gi|11499806 valyl-tRNA synthetase (valS) [Archaeoglobus fulgidus... 779 0.0
gb|AAK41179.1| Valyl-tRNA synthetase (valS) [Sulfolobus solfatar... 748 0.0
gb|AAG20602.1| (AE005130) valyl-tRNA synthetase; ValS [Halobacte... 712 0.0
emb|CAC11189.1| (AL445063) valyl-tRNA synthetase related protein... 535 e-151
dbj|BAB06757.1| (AP001517) valyl-tRNA synthetase [Bacillus halod... 520 e-146
sp|Q9ZCN6|SYV_RICPR VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 518 e-146
pir||SYBSVS valine--tRNA ligase (EC 6.1.1.9) - Bacillus stearoth... 509 e-143
sp|P11931|SYV_BACST VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 506 e-142
sp|Q05873|SYV_BACSU VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 502 e-141
pir||C72565 probable valyl-tRNA synthetase APE1805 - Aeropyrum p... 482 e-135
pir||D72206 valine--tRNA ligase (EC 6.1.1.9) - Thermotoga mariti... 481 e-134
sp|P36420|SYV_LACCA VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 444 e-123
sp|Q55522|SYV_SYNY3 VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 427 e-118
sp|P26499|SYI_METTM ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 420 e-116
sp|O27428|SYI_METTH ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 416 e-115
sp|Q9YF67|SYI_AERPE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 404 e-111
sp|Q9XDB4|SYI_FERPE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 400 e-110
emb|CAB75396.1| (AL139298) valyl tRNA synthetase [Streptomyces c... 397 e-109
sp|P46213|SYI_THEMA ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 395 e-109
sp|O58792|SYI_PYRHO ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 393 e-108
sp|Q9V072|SYI_PYRAB ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 391 e-107
sp|P56000|SYV_HELPY VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 389 e-107
sp|Q58357|SYI_METJA ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 386 e-106
gi|11498241 isoleucyl-tRNA synthetase (ileS) [Archaeoglobus fulg... 385 e-105
gb|AAF65673.1|AF208389_1 (AF208389) isoleucyl-tRNA synthetase [M... 376 e-103
sp|Q9ZK61|SYV_HELPJ VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 376 e-103
pir||E75554 valyl-tRNA synthetase - Deinococcus radiodurans (str... 374 e-102
sp|P96142|SYV_THETH VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 370 e-101
emb|CAB57581.1| (Y18930) isoleucyl-tRNA synthetase [Sulfolobus s... 369 e-100
pir||H81686 valyl-tRNA synthetase TC0576 [imported] - Chlamydia ... 369 e-100
gb|AAK41020.1| Isoleucine-tRNA synthetase (ileS) [Sulfolobus sol... 369 e-100
sp|O83998|SYV_TREPA VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 366 e-100
sp|P43834|SYV_HAEIN VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 365 1e-99
sp|Q9Z987|SYV_CHLPN VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 363 5e-99
pir||G83167 valyl-tRNA synthetase PA3834 [imported] - Pseudomona... 360 4e-98
pir||F81230 valyl-tRNA synthetase NMB0174 [imported] - Neisseria... 359 7e-98
sp|O84304|SYV_CHLTR VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 357 3e-97
pir||E82001 valyl-tRNA synthetase NMA0094 [imported] - Neisseria... 355 1e-96
pir||G81348 valine--tRNA ligase (EC 6.1.1.9) Cj0775c [imported] ... 354 2e-96
sp|O53175|SYV_MYCTU VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 352 9e-96
pir||E82913 valyl-tRNA synthetase UU267 [imported] - Ureaplasma ... 348 1e-94
sp|O51680|SYV_BORBU VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 339 1e-91
gb|AAG20324.1| (AE005106) isoleucyl-tRNA synthetase; IleS [Halob... 336 8e-91
sp|P07118|SYV_ECOLI VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 333 7e-90
emb|CAA29322.1| (X05891) valyl-tRNA synthetase [Escherichia coli] 333 7e-90
gb|AAA97155.1| (U14003) valyl-tRNA synthetase [Escherichia coli] 333 7e-90
gb|AAA24657.1| (J03497) valyl tRNA synthetase [Escherichia coli] 331 2e-89
dbj|BAB06264.1| (AP001515) isoleucyl-tRNA synthetase [Bacillus h... 330 6e-89
sp|Q45477|SYI_BACSU ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 329 1e-88
pir||T39630 valine-tRNA ligase precursor, mitochondrial - fissio... 328 1e-88
sp|P93736|SYV_ARATH VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 327 3e-88
gb|AAF63175.1|AC010657_11 (AC010657) T5E21.11 [Arabidopsis thali... 326 5e-88
sp|O51773|SYI_BORBU ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 326 9e-88
pir||E82068 valyl-tRNA synthetase VC2503 [imported] - Vibrio cho... 326 9e-88
gb|AAA35207.1| (J02719) valyl-tRNA synthetase [Saccharomyces cer... 325 1e-87
gi|6321531 mitochondrial and cytoplasmic valyl-tRNA synthetase; ... 324 3e-87
emb|CAB60428.1| (AL110500) contains similarity to Pfam domain: P... 319 8e-86
sp|P41972|SYI_STAAU ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 318 1e-85
pdb|1FFY|A Chain A, Insights Into Editing From An Ile-Trna Synth... 317 4e-85
pir||B82843 valyl-tRNA synthetase XF0134 [imported] - Xylella fa... 315 1e-84
sp|P75304|SYV_MYCPN VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 314 2e-84
pir||T34946 probable isoleucyl-tRNA synthetase - Streptomyces co... 314 4e-84
sp|P47576|SYV_MYCGE VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 311 2e-83
sp|P28350|SYV_NEUCR VALYL-TRNA SYNTHETASE, MITOCHONDRIAL PRECURS... 310 6e-83
sp|P56690|SYI_THETH ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 309 7e-83
gb|AAF58412.1| (AE003819) CG4062 gene product [Drosophila melano... 307 3e-82
sp|P41368|SYIP_STAAU ISOLEUCYL-TRNA SYNTHETASE, MUPIROCIN RESIST... 307 5e-82
pir||T51503 valine--tRNA ligase-like protein - Arabidopsis thali... 306 6e-82
sp|O66651|SYI_AQUAE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 301 3e-80
sp|O13651|SYIC_SCHPO ISOLEUCYL-TRNA SYNTHETASE, CYTOPLASMIC (ISO... 300 6e-80
sp|P57447|SYV_BUCAI VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 299 1e-79
pir||B81982 probable isoleucine--tRNA ligase (EC 6.1.1.5) NMA062... 297 4e-79
sp|O67411|SYV_AQUAE VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 294 3e-78
sp|Q21926|SYI_CAEEL PROBABLE ISOLEUCYL-TRNA SYNTHETASE, CYTOPLAS... 291 2e-77
pir||G81036 isoleucyl-tRNA synthetase NMB1833 [imported] - Neiss... 290 4e-77
pir||F81719 isoleucyl-tRNA synthetase TC0288 [imported] - Chlamy... 289 9e-77
sp|O84022|SYI_CHLTR ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 286 1e-75
sp|Q9Z972|SYI_CHLPN ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 285 2e-75
pir||C81552 isoleucyl-tRNA synthetase CP0665 [imported] - Chlamy... 285 2e-75
gi|6755953 valyl-tRNA synthetase 2 [Mus musculus] >gi|3986754|gb... 282 9e-75
gb|AAD26531.1|AF087141_1 (AF087141) valyl-tRNA synthetase [Mus m... 280 3e-74
gb|AAA81332.1| (M98326) valyl-tRNA synthetase [Homo sapiens] 280 4e-74
sp|P26640|SYV_HUMAN VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 280 4e-74
gi|5454158 valyl-tRNA synthetase 2 [Homo sapiens] >gi|11417740|r... 279 8e-74
sp|P43824|SYI_HAEIN ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 279 1e-73
sp|Q9ZHB3|SYI_STRPN ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 277 5e-73
sp|P49696|SYV_FUGRU VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 275 1e-72
pir||PN0474 valine--tRNA ligase (EC 6.1.1.9) (version 2) - human... 273 6e-72
gi|11429025 isoleucine-tRNA synthetase [Homo sapiens] >gi|730870... 269 1e-70
gi|11429023 isoleucine-tRNA synthetase [Homo sapiens] 269 1e-70
gi|4504555 isoleucine-tRNA synthetase [Homo sapiens] >gi|7770072... 269 1e-70
sp|P73505|SYI_SYNY3 ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 267 3e-70
pir||S17675 valine--tRNA ligase (EC 6.1.1.9) - human >gi|31545|e... 265 2e-69
emb|CAC12008.1| (AL445065) isoleucyl-tRNA synthetase related pro... 262 1e-68
dbj|BAB10327.1| (AB017061) isoleucyl-tRNA synthetase [Arabidopsi... 261 3e-68
dbj|BAA95147.1| (D28500) mitochondrial isoleucine tRNA synthetas... 259 1e-67
gi|6319395 cytoplasmic isoleucyl-tRNA synthetase; Ils1p [Sacchar... 257 5e-67
pir||C82559 isoleucyl-tRNA synthetase XF2418 [imported] - Xylell... 256 1e-66
sp|P57249|SYI_BUCAI ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 254 2e-66
gb|AAD56932.1|AF180145_24 (AF180145) isoleucyl-tRNA synthetase [... 254 2e-66
gb|AAF51821.1| (AE003597) CG11471 gene product [alt 1] [Drosophi... 254 2e-66
pir||G82894 isoleucyl-tRNA synthetase UU410 [imported] - Ureapla... 253 6e-66
sp|O83466|SYI_TREPA ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 253 7e-66
sp|P00956|SYI_ECOLI ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 251 2e-65
sp|Q9WY15|SYL_THEMA LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 251 3e-65
pir||B83077 isoleucyl-tRNA synthetase PA4560 [imported] - Pseudo... 250 5e-65
pir||D82293 isoleucyl-tRNA synthetase VC0682 [imported] - Vibrio... 249 1e-64
gb|AAF50346.1| (AE003553) CG5660 gene product [Drosophila melano... 247 4e-64
pir||T28995 hypothetical protein ZC513.4 - Caenorhabditis elegan... 243 8e-63
gb|AAA34712.1| (M19992) isoleucyl-tRNA synthetase (EC 6.1.1.5) [... 240 4e-62
sp|P36422|SYI_TETTH ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 240 5e-62
pir||T38777 probable valyl trna synthetase - fission yeast (Sch... 239 1e-61
dbj|BAA01304.1| (D10483) isoleucyl-tRNA ligase [Escherichia coli] 236 6e-61
gi|8922356 hypothetical protein FLJ10326 [Homo sapiens] >gi|7022... 235 1e-60
gi|11426198 hypothetical protein FLJ10326 [Homo sapiens] 235 1e-60
dbj|BAA28842.1| (AB008528) Valyl tRNA Synthetase [Trichomonas va... 235 2e-60
pir||D75307 leucyl-tRNA synthetase - Deinococcus radiodurans (st... 233 7e-60
sp|P41257|SYI_CAMJE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 231 3e-59
sp|P18330|SYI_PSEFL ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 231 3e-59
pir||T27465 hypothetical protein Y87G2A.m - Caenorhabditis elegans 230 5e-59
pir||B81309 isoleucine--tRNA ligase (EC 6.1.1.5) Cj1061c [import... 230 6e-59
gb|AAC41448.1| (L37104) transfer RNA-Ile synthetase [Thermotoga ... 229 8e-59
sp|P56456|SYI_HELPY ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 228 3e-58
pir||E75407 isoleucyl-tRNA synthetase - Deinococcus radiodurans ... 224 5e-57
sp|Q10765|SYI_MYCTU ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 222 1e-56
pir||A64379 isoleucine--tRNA ligase (EC 6.1.1.5) - Methanococcus... 222 2e-56
sp|Q58050|SYL_METJA LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 222 2e-56
sp|Q9ZJJ1|SYI_HELPJ ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 220 4e-56
gi|11499997 leucyl-tRNA synthetase (leuS) [Archaeoglobus fulgidu... 215 1e-54
sp|P75258|SYI_MYCPN ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 214 3e-54
sp|O58698|SYL_PYRHO LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 208 2e-52
sp|P46215|SYI_SULAC ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 206 7e-52
sp|Q9X7E5|SYI_MYCLE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 206 1e-51
sp|P73274|SYL_SYNY3 LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 201 3e-50
gb|AAF49539.1| (AE003528) CG5414 gene product [Drosophila melano... 199 1e-49
gb|AAK40902.1| Leucyl-tRNA synthetase (leuS-2) [Sulfolobus solfa... 197 4e-49
emb|CAB57710.1| (Y18930) isoleucyl-trna synthetase [Sulfolobus s... 197 4e-49
pir||T04047 isoleucine--tRNA ligase homolog F24G24.120 - Arabido... 197 6e-49
sp|Q04462|SYV_RAT VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (V... 194 5e-48
sp|O51267|SYL_BORBU LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 193 6e-48
pir||T41201 isoleucyl-trna synthetase - fission yeast (Schizosa... 192 1e-47
pir||T19442 hypothetical protein C25A1.7a - Caenorhabditis elega... 191 3e-47
sp|P56457|SYL_HELPY LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 188 2e-46
sp|Q9ZCU4|SYI_RICPR ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA ... 182 1e-44
sp|Q9YD97|SYL_AERPE LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 179 1e-43
sp|P46216|SYV_TRIVA VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 176 7e-43
gb|AAD36946.1|AF069441_6 (AF069441) putative leucyl tRNA synthet... 174 5e-42
dbj|BAB07000.1| (AP001518) leucyl-tRNA synthetase [Bacillus halo... 173 1e-41
emb|CAC11908.1| (AL445065) leucyl-tRNA synthetase related protei... 170 5e-41
sp|Q9ZJ63|SYL_HELPJ LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 168 3e-40
dbj|BAA28840.1| (AB008526) Valyl tRNA Synthetase [Trichomonas va... 166 8e-40
dbj|BAA28841.1| (AB008527) Valyl tRNA Synthetase [Trichomonas va... 166 1e-39
gb|AAK40823.1| Leucyl-tRNA synthetase (leuS-1) [Sulfolobus solfa... 165 2e-39
sp|P43827|SYL_HAEIN LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 134 4e-30
dbj|BAB14164.1| (AK022665) unnamed protein product [Homo sapiens] 131 4e-29
sp|Q9ZDB1|SYL_RICPR LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 128 3e-28
pir||G81698 leucyl-tRNA synthetase TC0481 [imported] - Chlamydia... 127 7e-28
pir||A41882 leucine--tRNA ligase (EC 6.1.1.4) - Bacillus subtili... 126 9e-28
sp|P36430|SYL_BACSU LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 126 9e-28
sp|O84211|SYL_CHLTR LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 126 9e-28
emb|CAA83769.1| (Z33122) Val-tRNA synthetase [Mycoplasma caprico... 126 1e-27
pir||H75133 leucyl-tRNA synthetase (leus) PAB1782 - Pyrococcus a... 125 2e-27
sp|P07813|SYL_ECOLI LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 125 3e-27
gb|AAB40843.1| (U82598) leucine tRNA synthetase [Escherichia coli] 125 3e-27
sp|O66680|SYLA_AQUAE LEUCYL-TRNA SYNTHETASE ALPHA SUBUNIT (LEUCI... 124 5e-27
emb|CAA29642.1| (X06331) leucyl-tRNA synthetase [Escherichia coli] 123 1e-26
sp|Q9Z930|SYL_CHLPN LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 121 4e-26
pir||E82590 leucyl-tRNA synthetase XF2176 [imported] - Xylella f... 120 5e-26
gb|AAG10490.1|AF279106_52 (AF279106) predicted leucyl-tRNA synth... 118 3e-25
gb|AAG20349.1| (AE005108) leucine-tRNA synthetase; LeuS [Halobac... 118 3e-25
dbj|BAB17162.1| (AP002868) putative leucyl-tRNA synthetase [Oryz... 116 8e-25
pir||G82260 leucyl-tRNA synthetase VC0956 [imported] - Vibrio ch... 115 2e-24
dbj|BAA24690.1| (AB010832) ORF3; putative leucyl-tRNA synthase [... 113 1e-23
pir||F82899 leucyl-tRNA synthetase UU371 [imported] - Ureaplasma... 113 1e-23
pir||F81312 leucine--tRNA ligase (EC 6.1.1.4) Cj1091c [imported]... 113 1e-23
sp|P57519|SYL_BUCAI LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE... 112 2e-23
pir||F81974 leucine--tRNA ligase (EC 6.1.1.4) NMA0559 [similarit... 108 2e-22
pir||G81029 leucine--tRNA ligase (EC 6.1.1.4) NMB1897 [similarit... 108 4e-22
pir||T01968 isoleucine--tRNA ligase homolog T9A4.4 - Arabidopsis... 104 5e-21
pir||T30889 valine--tRNA ligase (EC 6.1.1.9) - Giardia lamblia >... 103 1e-20
pir||E83148 leucyl-tRNA synthetase PA3987 [imported] - Pseudomon... 102 2e-20
sp|P36432|SYV_HAEPA VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) ... 90 8e-17
gb|AAB51589.1| (U93308) valyl tRNA synthetase [Arabidopsis thali... 85 3e-15
dbj|BAA28843.1| (AB008529) Valyl tRNA Synthetase [Trichomonas va... 84 7e-15
dbj|BAA28844.1| (AB008530) Valyl tRNA Synthetase [Trichomonas va... 84 7e-15
sp|Q09996|SYLC_CAEEL PROBABLE LEUCYL-TRNA SYNTHETASE (LEUCINE--T... 76 2e-12
>pir||G75014 valyl-tRNA synthetase (vals) PAB1255 - Pyrococcus abyssi (strain
Orsay) >gi|5459071|emb|CAB50557.1| (AJ248288) valyl-tRNA
synthetase (valS) [Pyrococcus abyssi]
Length = 891
Score = 1877 bits (4808), Expect = 0.0
Identities = 891/891 (100%), Positives = 891/891 (100%)
Query: 1 MLPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWI 60
MLPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWI
Sbjct: 1 MLPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWI 60
Query: 61 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAM 120
DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAM
Sbjct: 61 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAM 120
Query: 121 RKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAK 180
RKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAK
Sbjct: 121 RKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAK 180
Query: 181 AEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVGKKVK 240
AEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVGKKVK
Sbjct: 181 AEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVGKKVK 240
Query: 241 LPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENA 300
LPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENA
Sbjct: 241 LPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENA 300
Query: 301 GPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRV 360
GPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRV
Sbjct: 301 GPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRV 360
Query: 361 KDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIP 420
KDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIP
Sbjct: 361 KDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIP 420
Query: 421 AREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEA 480
AREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEA
Sbjct: 421 AREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEA 480
Query: 481 KKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKS 540
KKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKS
Sbjct: 481 KKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKS 540
Query: 541 YGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHI 600
YGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHI
Sbjct: 541 YGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHI 600
Query: 601 KDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYI 660
KDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYI
Sbjct: 601 KDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYI 660
Query: 661 EMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHL 720
EMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHL
Sbjct: 661 EMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHL 720
Query: 721 LSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESYDDLKL 780
LSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESYDDLKL
Sbjct: 721 LSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESYDDLKL 780
Query: 781 IEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKNNAESIA 840
IEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKNNAESIA
Sbjct: 781 IEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKNNAESIA 840
Query: 841 REIKENGKVEFEIDGEKVELTKEDVMIKKEVFSEGERVETAVVDDIVILFF 891
REIKENGKVEFEIDGEKVELTKEDVMIKKEVFSEGERVETAVVDDIVILFF
Sbjct: 841 REIKENGKVEFEIDGEKVELTKEDVMIKKEVFSEGERVETAVVDDIVILFF 891
>pir||D71457 valine--tRNA ligase (EC 6.1.1.9) - Pyrococcus horikoshii
>gi|3256704|dbj|BAA29387.1| (AP000001) 896aa long
hypothetical valyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 896
Score = 1797 bits (4602), Expect = 0.0
Identities = 834/891 (93%), Positives = 876/891 (97%)
Query: 1 MLPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWI 60
MLPK YDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWI
Sbjct: 6 MLPKNYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWI 65
Query: 61 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAM 120
DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAM
Sbjct: 66 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAM 125
Query: 121 RKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAK 180
RKQFIRIGYSADWDLEYHTMDDWYKAAVQ+SLLEFYKKGLIYREEHPVYWCPKCRTSLAK
Sbjct: 126 RKQFIRIGYSADWDLEYHTMDDWYKAAVQRSLLEFYKKGLIYREEHPVYWCPKCRTSLAK 185
Query: 181 AEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVGKKVK 240
AEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVGKKVK
Sbjct: 186 AEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVGKKVK 245
Query: 241 LPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENA 300
LPI+EREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVII INEDGTMNENA
Sbjct: 246 LPIFEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIVINEDGTMNENA 305
Query: 301 GPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRV 360
GPYAGLK+EEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFI+V
Sbjct: 306 GPYAGLKIEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIKV 365
Query: 361 KDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIP 420
KD DEI+KVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIP
Sbjct: 366 KDLIDEIIKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIP 425
Query: 421 AREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEA 480
AREEDLPVDPRFDKPPV+KCPVCGAEIEPVTDVLDCWVDSSITPLIIT+WHEAIKGDEEA
Sbjct: 426 AREEDLPVDPRFDKPPVDKCPVCGAEIEPVTDVLDCWVDSSITPLIITKWHEAIKGDEEA 485
Query: 481 KKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKS 540
KKWFEHNFPTALRPQGTDIIRTWAFYTI RT+ LTGKKPWKDIVINGMVAGPDGRKMSKS
Sbjct: 486 KKWFEHNFPTALRPQGTDIIRTWAFYTILRTYVLTGKKPWKDIVINGMVAGPDGRKMSKS 545
Query: 541 YGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHI 600
YGNVV+P+EVIPKYGADALRLWTALAPPGEDHPFKWETVDYN+RFLQKVWNIYRFAERHI
Sbjct: 546 YGNVVSPEEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNYRFLQKVWNIYRFAERHI 605
Query: 601 KDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYI 660
KDFDYEKY+D+ELEPLD+WILSRLHRIIKFATEELERYRFNLITREL+TFIWHEVADDYI
Sbjct: 606 KDFDYEKYRDVELEPLDKWILSRLHRIIKFATEELERYRFNLITRELITFIWHEVADDYI 665
Query: 661 EMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHL 720
EM+KYRLYG+DEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHA+FK+KIGEKSVHL
Sbjct: 666 EMIKYRLYGEDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAIFKEKIGEKSVHL 725
Query: 721 LSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESYDDLKL 780
LSWPEYREDRIDE+AEK+GELARK+VSEMRKYKNSHG+PLNAKL+HVAIYAL+SY+ LKL
Sbjct: 726 LSWPEYREDRIDEEAEKIGELARKIVSEMRKYKNSHGLPLNAKLKHVAIYALDSYERLKL 785
Query: 781 IEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKNNAESIA 840
IE+DIAGTMNIE+LEI KGEP LEERIVEVKPNYK IGP+YGKLVPRIV++L+ NAESI
Sbjct: 786 IERDIAGTMNIERLEIVKGEPHLEERIVEVKPNYKNIGPKYGKLVPRIVQYLRENAESIV 845
Query: 841 REIKENGKVEFEIDGEKVELTKEDVMIKKEVFSEGERVETAVVDDIVILFF 891
REIKE GK EFE++G+KVELTKED+ ++KEVFSEGE+VET+VVDD+VI+FF
Sbjct: 846 REIKEKGKAEFEVEGKKVELTKEDITVRKEVFSEGEKVETSVVDDVVIVFF 896
>sp|Q58413|SYV_METJA VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|2129352|pir||F64425 valine--tRNA ligase (EC 6.1.1.9)
- Methanococcus jannaschii >gi|1591666|gb|AAB99009.1|
(U67543) valyl-tRNA synthetase (valS) [Methanococcus
jannaschii]
Length = 878
Score = 867 bits (2215), Expect = 0.0
Identities = 446/897 (49%), Positives = 601/897 (66%), Gaps = 35/897 (3%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+PK Y+ EIE + QK W E KIYK+ + NKP Y IDTPPP+ +G LHLGH L+ T++D
Sbjct: 3 MPKDYNI-EIEKQIQKKWEESKIYKFDEESNKPPYIIDTPPPYPTGRLHLGHALNWTYMD 61
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPE--EFLKKCVEWTWQAIEA 119
IIARYKRM+G+NVLFPQG+D HGLPTE+KVE+ GITK + +F + C+E T + IE
Sbjct: 62 IIARYKRMKGFNVLFPQGWDCHGLPTEVKVEEIHGITKSDVDRHKFRELCIELTKENIEK 121
Query: 120 MRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLA 179
MR+Q +G S DWD EY TM Y Q + + YK GLIYR + PV WCP+C+T++A
Sbjct: 122 MRRQIKSLGISIDWDKEYITMTPEYIKKSQTAFVRMYKDGLIYRGKFPVNWCPRCQTAIA 181
Query: 180 KAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVGKKV 239
AEV Y E E L YIK P ADG G++ IATTRPELM ACVA+ VHP+DERYKHL+GK+
Sbjct: 182 FAEVEYKERESKLNYIKFPAADGEGHLLIATTRPELMAACVAILVHPEDERYKHLIGKEF 241
Query: 240 KLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNEN 299
+P++ +V +LADEDV+ FGTGAV CT+GD+ D++W R+ L + AI+E G + E
Sbjct: 242 IVPLFGHKVKLLADEDVEKEFGTGAVMVCTFGDKTDVLWVNRHKLEIKKAIDEKGELTEI 301
Query: 300 AGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIR 359
AG Y GLK EEAR+KI EDL+K G L K+E IK V C PIE++ +QWF+
Sbjct: 302 AGKYKGLKTEEAREKIIEDLKKEGYLVKQEPIKQNV---GVCWRCKTPIEIIVTEQWFVN 358
Query: 360 VKDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVC-KNGHI 418
V+ ++ +VA EI W PE M +RL +W E MDWDWVISRQR+F TP P W C K G++
Sbjct: 359 VRKLIPKVREVADEIKWIPEHMKIRLLNWIEDMDWDWVISRQRIFATPIPVWYCPKCGNV 418
Query: 419 IPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDE 478
+ A+EEDLP+DP +KC ++ P TDVLD W+DSSITP++IT+W
Sbjct: 419 VVAKEEDLPIDPTKTGYVCDKCG--NKDLIPETDVLDTWMDSSITPMVITKW-------L 469
Query: 479 EAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMS 538
+ K+FE ++P LRPQG DIIRTWAFYTI ++ LTGKKPW +IVINGMV G DG KMS
Sbjct: 470 DDDKFFEKHYPVQLRPQGHDIIRTWAFYTIVKSVALTGKKPWDEIVINGMVFGEDGHKMS 529
Query: 539 KSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAER 598
KS GNVV PDE+I KYGADALRLW + + G+D F W+ VDY +RFL+K WN RFA+
Sbjct: 530 KSRGNVVEPDEIIAKYGADALRLWASNSVVGDDVQFLWKEVDYGYRFLRKSWNACRFAKM 589
Query: 599 HIK-DFDYEKYKDIEL-EPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVA 656
HI D E K +E+ P+D WILS+L R+I+ ++LE YRFN I E+ F+WHE
Sbjct: 590 HISDDIIDELKKPMEISNPIDLWILSKLQRLIERVDKDLENYRFNTIV-EIYKFVWHEFC 648
Query: 657 DDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEK 716
D+YIEMVKYRLYGDDEE+K +A+ LY ++ V+ LL PF PH ++ I D +
Sbjct: 649 DNYIEMVKYRLYGDDEEAKKEARWTLYYVIDKVVRLLCPFAPHFSDYIAEIYKIDNLH-- 706
Query: 717 SVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYA--LES 774
S+PE I+E+AEK GE+A+ V +R++K + GM LNA L++V IY E+
Sbjct: 707 ----FSFPEVDNRFINEEAEKFGEIAKNTVISIRRFKANSGMALNAPLKYVEIYTEDEET 762
Query: 775 YDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKN 834
Y L +DI GT+ IE+L+I KG+P LE +IVE+ P+ +IGP + K +++ +KN
Sbjct: 763 YLALNKTAEDIKGTLKIEELKIIKGKPALESKIVEIIPDKSKIGPEFKKNAKAVMDLIKN 822
Query: 835 -NAESIAREIKENGKVEFEIDGEKVELTKEDVM-IKKEVFSEGERVETAVVDDIVIL 889
+ E++ + I E + E+ + + KE + +K+ +F EGE V++ ++ ++ +
Sbjct: 823 ADEETLEKIINEGLETEYGV------IRKEHIKDVKRALFCEGEEVDSVDIEGVLAM 873
>sp|O26861|SYV_METTH VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437639|pir||E69202 valine--tRNA ligase (EC 6.1.1.9)
MTH767 - Methanobacterium thermoautotrophicum (strain
Delta H) >gi|2621857|gb|AAB85270.1| (AE000855)
valyl-tRNA synthetase [Methanobacterium
thermoautotrophicum]
Length = 897
Score = 813 bits (2077), Expect = 0.0
Identities = 416/891 (46%), Positives = 565/891 (62%), Gaps = 35/891 (3%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+PK Y+ ++ E KWQK W EE IY++ KP Y IDTPPP+ +G++H+GHVL+ ++D
Sbjct: 26 IPKDYN-HKNEVKWQKKWQEEDIYRFIGSGTKPRYIIDTPPPYPTGSIHMGHVLNWVYMD 84
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP--EEFLKKCVEWTWQAIEA 119
IIAR+KRMRG++VLFPQG+D HGLPTE+KVE+ I K EEF + CVE T + I
Sbjct: 85 IIARFKRMRGFDVLFPQGWDCHGLPTEVKVEETHNIKKSDVSREEFRRLCVELTQENIRM 144
Query: 120 MRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLA 179
M++Q R+G+S DW+ E+ TM Y Q S L Y+ GLIY+ HPV WCP+C T++A
Sbjct: 145 MKEQMQRLGFSQDWNHEFVTMTPEYMRRTQLSFLRMYRDGLIYQGVHPVNWCPRCETAIA 204
Query: 180 KAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVGKKV 239
AEV Y+E E L Y++ P+ +I IATTRPELM ACVAV VHPDDER++ K +
Sbjct: 205 FAEVEYIENETNLNYVRFPVEGADEHITIATTRPELMAACVAVVVHPDDERFREFEDKLI 264
Query: 240 KLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNEN 299
++P++ ++V ++ D +VDP FGTGAV CT+GD+ D+ W R+ L VI AI+E G M E
Sbjct: 265 EVPLFGQKVKLIKDPEVDPEFGTGAVMVCTFGDKTDVSWVNRHGLDVIDAIDERGYMTEA 324
Query: 300 AGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIR 359
AG Y GL + E ++KI EDLE G L KKE ++ V C PIE+L KKQWF+
Sbjct: 325 AGKYQGLTIAECKEKIVEDLENEGFLLKKEPVRQNV---GTCWRCKTPIEILVKKQWFVA 381
Query: 360 VKDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKN-GHI 418
VK ++ + A+E+ W P M RL +W SMDWDW ISRQR+F TP P W C G +
Sbjct: 382 VKKLIPQVREAAEEMKWVPGHMKTRLLNWTGSMDWDWCISRQRIFATPIPVWYCSECGRV 441
Query: 419 IPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDE 478
A EE LPVDP D P + C E DVLD W+DSSI+PL + W +
Sbjct: 442 HVADEEMLPVDPTRDGPGI-TCECGSTEFIGEEDVLDTWMDSSISPLSVAGWPD------ 494
Query: 479 EAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMS 538
+ + FP LRPQG DIIRTWAFYTI R LTG+KP+ +IVINGMV G DG KMS
Sbjct: 495 ---ESYRELFPADLRPQGHDIIRTWAFYTILRCMALTGEKPFSEIVINGMVFGEDGHKMS 551
Query: 539 KSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAER 598
KS GNV+AP+EV+ YGADALRLW A + PG D PF W+ V Y ++FL+K WN +RF
Sbjct: 552 KSRGNVIAPEEVLEDYGADALRLWAAGSVPGSDVPFAWKDVKYGYKFLRKFWNAFRFISI 611
Query: 599 HIKDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADD 658
H+ + ++E P+DRWILSRL ++ TE L+ Y F + TFIWH+ D+
Sbjct: 612 HLTE-----NPEVEARPMDRWILSRLMNLVAEVTESLDDYNFAAAVNRVQTFIWHDFCDE 666
Query: 659 YIEMVKYRLYGD-DEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKS 717
YIE VKYRLY D D ES++ A+ L +L + LLAP PH TEE++ +GE S
Sbjct: 667 YIEAVKYRLYSDEDPESRMAAQNTLRMVLDTCLRLLAPVAPHFTEEVH-----QHVGEGS 721
Query: 718 VHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYA-LESYD 776
+HL WPE+ + +D + E+ G+LA +++ E+R++K+S MPLNA L+ IY ES +
Sbjct: 722 IHLRGWPEHIPEIVDPEIERSGDLAVEIIGEIRRFKSSSKMPLNAPLKAATIYTDNESAE 781
Query: 777 DLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKN-N 835
+K DIAGTMNI + + G+P++ ER VE++P ++IGP + P I+ L +
Sbjct: 782 MIKPFLDDIAGTMNIGDISLVAGKPEITERAVELEPRMEKIGPEFRSDAPAIISWLTGAD 841
Query: 836 AESIAREIKENGKVEFEIDGEKVELTKEDVMIKKEVF-SEGERVETAVVDD 885
+ EI+ NG E E++G + LT + + +KEV + GERV+ +D+
Sbjct: 842 PHEVYEEIQRNG--EIEVEGNR--LTMDHISFRKEVIGTAGERVDVLNLDE 888
>gi|11499806 valyl-tRNA synthetase (valS) [Archaeoglobus fulgidus]
>gi|3122909|sp|O28059|SYV_ARCFU VALYL-TRNA SYNTHETASE
(VALINE--TRNA LIGASE) (VALRS) >gi|7437638|pir||H69527
valyl-tRNA synthetase (valS) homolog - Archaeoglobus
fulgidus >gi|2648303|gb|AAB89032.1| (AE000952)
valyl-tRNA synthetase (valS) [Archaeoglobus fulgidus]
Length = 863
Score = 779 bits (1990), Expect = 0.0
Identities = 407/880 (46%), Positives = 553/880 (62%), Gaps = 38/880 (4%)
Query: 4 KKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDII 63
K YD +E+E KW K W +E +Y + + KP Y IDTPPP+ +G+ H+GH L+ ID I
Sbjct: 5 KDYDAHEVEEKWLKLWKDE-MYYFDWNSEKPHYIIDTPPPYPTGSFHIGHALNWCIIDFI 63
Query: 64 ARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITK-DQP-EEFLKKCVEWTWQAIEAMR 121
ARYKRM GY V+FPQG+D HGLPTE+KVE+++GI K D P +EF + CVE+T + I MR
Sbjct: 64 ARYKRMNGYEVMFPQGWDCHGLPTEVKVEEKYGIKKGDIPRDEFRRLCVEFTEENIAKMR 123
Query: 122 KQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKA 181
+ R+GYS DW EY TM Y + Q S + Y KGLIYR+ HPV +CP+C T++A A
Sbjct: 124 ETARRMGYSIDWSKEYITMYPEYYSKTQLSFVRMYNKGLIYRDYHPVVFCPRCETTIALA 183
Query: 182 EVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVGKKVKL 241
E+ Y + + L YIK + IATTRPEL+PACVA+ VHPDDER KHL+GKKV++
Sbjct: 184 EIEYRQGKTKLNYIKF-----DDDVIIATTRPELIPACVAIAVHPDDERNKHLIGKKVRV 238
Query: 242 PIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAG 301
P EV ++ADE+VDP FGTG V CT+GD QD+ W K++ L + + DG +NE AG
Sbjct: 239 PTTPYEVEVIADEEVDPEFGTGVVMICTFGDRQDVKWWKKHKLELRNIVGRDGRLNEKAG 298
Query: 302 PYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVK 361
YAG+ + EAR+ I EDL+K G L K+ +I H V C P+E++P +QWF++V+
Sbjct: 299 RYAGMTIPEAREAILEDLKKEGKLLKQVEIDHNVGTCWR---CKTPVEIIPAEQWFVKVE 355
Query: 362 DFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKN-GHIIP 420
++I++ AK I W PE M+ RL+ W +SM+WDWVISRQR+F TP P W CKN G ++
Sbjct: 356 K--EKILEAAKRIKWVPEHMYSRLESWVQSMEWDWVISRQRIFATPIPAWYCKNCGEVVV 413
Query: 421 AREEDLPVDPRFDKPPVEKCPVCGA-EIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEE 479
A+EE LPVDP +PP E CP CG+ E TDVLD W+DSSITPL+I W
Sbjct: 414 AKEEWLPVDPTATQPP-EPCPKCGSTEFRGETDVLDTWMDSSITPLMICGWPSL------ 466
Query: 480 AKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSK 539
+PT LRPQG DIIRTWAFYTI R+ L G+ PW +IVINGMV G DGRKMSK
Sbjct: 467 ------KEYPTHLRPQGHDIIRTWAFYTILRSLALEGQIPWYEIVINGMVFGEDGRKMSK 520
Query: 540 SYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERH 599
S GNV+ P+EV+ KYG DALR W A G+D F W+ V RF QK W+I RF H
Sbjct: 521 SLGNVIVPEEVVEKYGVDALRQWAASGVIGDDIIFNWKDVIAASRFQQKFWSITRFTLMH 580
Query: 600 IKDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDY 659
I D+ + L DRWILS+L+R++ + ++ YRF+ + + TF W+E AD+Y
Sbjct: 581 ISDYTPSEEDKKLLRDADRWILSKLNRLVGEVRKHMDEYRFDEAIKAIRTFTWYEYADNY 640
Query: 660 IEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVH 719
+E+VK RLY EE K AK L L + LLAP P + EE + E SVH
Sbjct: 641 LEIVKNRLYSGSEEEKRAAKFVLSYALDVLTRLLAPITPFMAEECW-----SHFREGSVH 695
Query: 720 LLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESYDDLK 779
L S+P E+ +DE+AEK GE +++V+ +RK+K+ G+ LNA L+ + +Y+ D L
Sbjct: 696 LQSYPVVEEEFLDERAEKAGEEIKEIVAAVRKFKHDKGLALNAPLKKLIVYS--KLDGLD 753
Query: 780 LIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKNNAESI 839
+ +DIAG N E +EI P++ ER+ E+KP + IGP + + +++ + + ++
Sbjct: 754 V--RDIAGATNSE-VEIVTEMPEVRERVKELKPKFAIIGPMFREKAKTLIKAVGSLSKEE 810
Query: 840 AREIKENGKVEFEIDGEKVELTKEDVMIKKEVFSEGERVE 879
+ + G ++ +DG VE+ E E EG VE
Sbjct: 811 KERLLKEGAIQVNLDGASVEVKAEWFEAVTEKSIEGREVE 850
>gb|AAK41179.1| Valyl-tRNA synthetase (valS) [Sulfolobus solfataricus]
Length = 842
Score = 748 bits (1911), Expect = 0.0
Identities = 376/823 (45%), Positives = 532/823 (63%), Gaps = 29/823 (3%)
Query: 3 PKKYDPNEIEPKWQKYWLEEK----IYKYRLDENK-PSYAIDTPPPFTSGTLHLGHVLSH 57
PK Y+P EIE KWQK WL E+ ++++R +++K P + IDTPPPFTSG LH+GH
Sbjct: 41 PKHYNPKEIEEKWQKIWLSEEYWRDVFRFRDEDDKAPRFVIDTPPPFTSGELHMGHAYWV 100
Query: 58 TWIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAI 117
T D I R+KR+ GYNVL PQG+D GLPTELKV+ + GI KD + FL+KC+EWT + I
Sbjct: 101 TIADTIGRFKRLEGYNVLLPQGWDTQGLPTELKVQYKLGIPKDNRQLFLQKCIEWTEEMI 160
Query: 118 EAMRKQFIRIGYSADWD-LEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRT 176
+ M++ IR+GY +W+ EY T + Y+ +QKSL++ YK LI E PV WCPKC T
Sbjct: 161 KKMKEAMIRLGYRPEWERFEYKTYEPKYRKIIQKSLIDMYKMNLIEMREGPVIWCPKCET 220
Query: 177 SLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVG 236
+LA++EVGY+E+EG L YIK PL +G G I IATTRPEL+ A A+ V+P DERYK+LVG
Sbjct: 221 ALAQSEVGYLEKEGILAYIKFPLKEG-GEIVIATTRPELLAATQAIAVNPMDERYKNLVG 279
Query: 237 KKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTM 296
K +PI+ EV I++D DV+ FGTGAV TYGD QDI WQ +YNLP+ + ++E G +
Sbjct: 280 KIALVPIFNIEVKIISDADVEKEFGTGAVMISTYGDPQDIKWQLKYNLPIKVIVDEKGRI 339
Query: 297 NENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQW 356
G GLK+E+AR K+ E L+ G L K EKIKH VL H ERS C++P+E L KKQ
Sbjct: 340 INTNGILDGLKIEQARNKMIELLKTKGYLVKVEKIKHNVLSHVERSDCLSPVEFLVKKQI 399
Query: 357 FIRVKDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNG 416
+I+V D ++++ K++ + P M L+DW +S++WDW I+RQR++GTP PFW C+NG
Sbjct: 400 YIKVLDKKQKLLEEYKKMKFKPARMSYYLEDWIKSIEWDWNITRQRIYGTPLPFWYCENG 459
Query: 417 HIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKG 476
H++PA+EEDLP+DP PP+EKCP+CG+E++PVTDV D W+DSS+T L +T+++
Sbjct: 460 HLVPAKEEDLPIDPIKTSPPLEKCPLCGSELKPVTDVADVWIDSSVTVLYLTKFY----- 514
Query: 477 DEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRK 536
E K F FP +LR QGTDIIRTW FYT FRT L P+ +++NG V GPDG +
Sbjct: 515 --EDKNVFNRTFPASLRLQGTDIIRTWLFYTFFRTLMLANNVPFTTVLVNGQVLGPDGTR 572
Query: 537 MSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFA 596
MSKS GNVV+P + + +GADA+R+ A G+D PFKW+ V LQK+WN R
Sbjct: 573 MSKSKGNVVSPLDRVNDFGADAIRMALLDASIGDDFPFKWDIVKGKKMLLQKLWNASRLV 632
Query: 597 ERHIKDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVA 656
I +K K + + +D+WIL + + A E Y F L+ +EL + W VA
Sbjct: 633 YPFIAKQRLDKPKSLHI--VDKWILQEHKKFVTKAINAYENYDFYLVLQELYNYFWEIVA 690
Query: 657 DDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEK 716
D+Y+EM+K+RL+ DD AK + ++ ++++LL P PHITEEIY +F K K
Sbjct: 691 DEYLEMIKHRLFDDDN----SAKYTIQRIIRDIIILLHPIAPHITEEIYSRLFGHK---K 743
Query: 717 SVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESYD 776
SV L P+ + +++ ++LGE+ +K S +R K + + +N + V +YA +
Sbjct: 744 SVLLEELPKVDDIEENKRIDELGEVIKKTNSLIRSEKIKNRLSMNTPVS-VKLYASKQVI 802
Query: 777 DL-KLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIG 818
+L ++ D+ T+ + LE+ + E VE+K + +G
Sbjct: 803 ELINEVKDDVMKTLKVTNLELIES----NEEKVEIKTANQSMG 841
>gb|AAG20602.1| (AE005130) valyl-tRNA synthetase; ValS [Halobacterium sp. NRC-1]
Length = 881
Score = 712 bits (1818), Expect = 0.0
Identities = 389/887 (43%), Positives = 526/887 (58%), Gaps = 33/887 (3%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
LP YDPN IEPKWQ W E +Y++ E+ Y IDTPPP+ SG LHLGH L ++ID
Sbjct: 4 LPDSYDPNSIEPKWQDEWQERDVYRFDPSESDTQYVIDTPPPYPSGNLHLGHALGWSYID 63
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITK-DQP-EEFLKKCVEWTWQAIEA 119
+ARY+R++G VLFPQG+D HGLPTE+KVE+ I + D P +EF + C++WT I+
Sbjct: 64 FVARYRRLKGDAVLFPQGWDCHGLPTEVKVEEVNDIHRTDVPSDEFREMCIDWTEDRIDE 123
Query: 120 MRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLA 179
M+ +G+S DWD EY TMD Y Q+S E G++YR+EHPV WCP+C T++A
Sbjct: 124 MKATMQELGFSQDWDSEYRTMDPEYWGKTQESFSEMADAGMVYRDEHPVNWCPRCETAIA 183
Query: 180 KAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVGKKV 239
AEV ++ EG L+Y+ D +G I IATTRPEL+ ACV + V PDD+RY +G
Sbjct: 184 DAEVENIDREGTLHYVTFDGVD-NGDIEIATTRPELLAACVGIVVSPDDDRYADRIGDTF 242
Query: 240 KLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNEN 299
++P++ ++V +LAD+DVD +FG+GAV CT+GD+QD+ W ++L + EDG +NE
Sbjct: 243 EVPLFGQDVELLADDDVDADFGSGAVMVCTFGDKQDVEWWMDHDLDLRTVFTEDGHLNEA 302
Query: 300 AGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIR 359
AG +AGL +++A+ ++AE+L+ G L E + V C IE+L K+QWF+
Sbjct: 303 AGEFAGLAIDDAKTQVAEELDDQGYLNDTEPTEQSV---GSCWRCDTAIEILSKEQWFVE 359
Query: 360 VKDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKN-GHI 418
V D I+ A + W PE M RL +W E MDWDWVISRQRVF TP P W C GH
Sbjct: 360 VDQ--DRILDAAADAEWVPEHMHDRLVEWTEGMDWDWVISRQRVFATPIPAWECNECGHW 417
Query: 419 IPAREEDLPVDPRFDKPPVEKCPVCGA-EIEPVTDVLDCWVDSSITPLIITRWHEAIKGD 477
A E PVDP D P VE CP CG + TDV+D W+DSSITPL ++ W E D
Sbjct: 418 EIAGREQAPVDPTEDDPAVEACPECGGDDWAGETDVMDTWMDSSITPLHLSGWPEGTTLD 477
Query: 478 EEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKM 537
E FE LRPQG DIIRTWAFYT+ RT LT ++PW D+++NGMV G DG KM
Sbjct: 478 E-----FE---SVDLRPQGHDIIRTWAFYTLLRTGALTDEQPWDDVLVNGMVFGEDGNKM 529
Query: 538 SKSYGNVVAPDEVIPKYGADALRLWTAL-APPGEDHPFKWETVDYNFRFLQKVWNIYRFA 596
SKS GN V PDE I +Y ADA+R AL PG D F+W+ V RFL K+WNI +F+
Sbjct: 530 SKSRGNFVQPDEAIAEYSADAVRQALALGGRPGSDVQFQWKEVKSASRFLTKLWNITKFS 589
Query: 597 ERHIKDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVA 656
H D D +D DRW+LS L + + E + YRF+ R L F W ++A
Sbjct: 590 TGHF-DEDTPAIQDPAYRDADRWLLSELSTVCEDVDEAMSEYRFDRALRSLREFAWEDLA 648
Query: 657 DDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEK 716
DDY+E+VK RLY + A+ LY + V LLAPF PH TEEI+ ++ E
Sbjct: 649 DDYVELVKGRLYNGRPGERAAAEHTLYTAVTAVTRLLAPFSPHTTEEIWQSL---PGTEG 705
Query: 717 SVHLLSWP--EYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALES 774
SVH ++P EYR D AE G+ +V E+R +K+ GMPLNA L+ V +Y +S
Sbjct: 706 SVHAATFPSVEYR----DADAELAGKRIAEVAREIRAWKSDQGMPLNADLDRVELYFDDS 761
Query: 775 YDD-LKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHL- 832
DD +L D++ T+N + + G P +E V+V + IGP + ++E +
Sbjct: 762 DDDAARLDTYDLSETVN-APIRLIDGRPDVELVPVDVDGDDSEIGPEFRSDAGTVMEAIA 820
Query: 833 KNNAESIAREIKENGKVEFEIDGEKVELTKEDVMIKKEV-FSEGERV 878
+ +I +I V E DGE +L + + + +E S GE V
Sbjct: 821 AADPAAIQAQIHSGDTVTVEADGESFDLDADWLTVTEEYRASSGEEV 867
>emb|CAC11189.1| (AL445063) valyl-tRNA synthetase related protein [Thermoplasma
acidophilum]
Length = 791
Score = 535 bits (1364), Expect = e-151
Identities = 307/807 (38%), Positives = 458/807 (56%), Gaps = 40/807 (4%)
Query: 7 DPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARY 66
D N++E KW +YW E+ +Y++ + +AIDTPPP SG +H+GH S+ ID IARY
Sbjct: 4 DVNQMEEKWIRYWDEKDVYRFEPADRDKVFAIDTPPPTVSGKMHMGHSFSYPHIDFIARY 63
Query: 67 KRMRGYNVLFPQGFDNHGLPTELKVEKEFGI--TKDQPEEFLKKCVEWTWQAIEAMRKQF 124
KRMRGY+V FP GFD++GLPTE VEKE GI + EEF++ C E + + +++ + +
Sbjct: 64 KRMRGYHVFFPWGFDDNGLPTERYVEKETGIKPSDSNVEEFIRLCKEISESSEKSLLEGW 123
Query: 125 IRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVG 184
RIG S + Y T Q L+ +KG +YR+ P CP C+TS+++ E+
Sbjct: 124 KRIGMSCYFKDYYVTSSPESIRISQSMFLDLVRKGRVYRDLAPSIRCPTCKTSISQIEMK 183
Query: 185 YVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVGKKVKLPIY 244
E L YI + D + IATTRPE++ +CVAVFV+PDD RY+ L+GK+ +PI+
Sbjct: 184 DQEMHTKLVYINFSVGDRP--LTIATTRPEMLGSCVAVFVNPDDARYRDLIGKEATVPIF 241
Query: 245 EREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYA 304
V I+AD VD NFGTGA CT+GD+ D+ K+YNLP+ I+I++DG M E AGP
Sbjct: 242 GNHVRIMADASVDMNFGTGAEMVCTFGDQNDLDLWKKYNLPLKISIDKDGRMTEEAGPLK 301
Query: 305 GLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFT 364
GL + +ARKKI E L + G + K+E IKH V H C PIE+ +KQWFI+ D
Sbjct: 302 GLSISDARKKIVEILREGGHVVKEESIKHSVNTH---ERCGTPIEIFIEKQWFIKYLDLK 358
Query: 365 DEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKN-GHIIPARE 423
D ++ ++I W PE M +R ++W + WDW+ISRQR +G PFP W C + G+ + A E
Sbjct: 359 DAFIENGRKIEWTPEYMRVRYENWVNGLKWDWLISRQRYYGVPFPVWYCADCGNTVYADE 418
Query: 424 EDLPVDPRFDKPPVEKCPVCGA-EIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKK 482
+LPVDPR KP +KC CG+ + P DV+D W SS+TP I H +
Sbjct: 419 SELPVDPRIQKPS-KKCDRCGSTNLVPERDVMDTWATSSLTPRIALT-HFGL-------- 468
Query: 483 WFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYG 542
F+ +P LR QG DII WAF TI R+ + PW I+I+G V G KMSKS G
Sbjct: 469 -FDKYYPEDLRGQGHDIISFWAFTTIARSKIHDDRIPWFRIMISGNVYDMYGEKMSKSKG 527
Query: 543 NVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKD 602
N+V +I KYGADALR W + G+D K + R + K++N + + D
Sbjct: 528 NIVDIYSMIDKYGADALRFWASTVSQGDDIRIKDQDFTRGRRTVIKMYNAKKLIDILKGD 587
Query: 603 FDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEM 662
++D++ P++RWIL+ RI++ T ++ Y + L TF W+ D+Y+EM
Sbjct: 588 RKIRLFEDVK-HPVNRWILTEDSRIMETITTHMDNYEVSKARTALDTFFWNVFCDNYLEM 646
Query: 663 VKYRLY----GDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEK-S 717
+K + D ++ + +++ +V AP +P I EEIY + D G K S
Sbjct: 647 IKPIIQKASAAGDYDTVDETVYTASKVMLDVAKAYAPIMPFIAEEIYQTI--DFPGRKIS 704
Query: 718 VHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYA----LE 773
+H+ SWP+ + R + E++ + V+ +R K++ + + +++ ++ +E
Sbjct: 705 IHVDSWPDEKR-RYSDANEEVSYIV-SVIDAIRSAKSAAKVSVGTRVKVASVKGRKDLIE 762
Query: 774 SYDDLKLIEKDIAGTMNIEKLEIFKGE 800
Y DL ++G + I+ +EI G+
Sbjct: 763 KYRDL------LSGMLRIDSMEIADGD 783
>dbj|BAB06757.1| (AP001517) valyl-tRNA synthetase [Bacillus halodurans]
Length = 880
Score = 520 bits (1325), Expect = e-146
Identities = 332/896 (37%), Positives = 486/896 (54%), Gaps = 57/896 (6%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+P KY P +IE KW +YW+E K ++ DE K Y I PPP +G LHLGH D
Sbjct: 8 MPTKYHPQDIESKWYEYWIEGKFFEATSDETKKPYTIVIPPPNVTGKLHLGHAWDTALQD 67
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVE---KEFGITKDQ--PEEFLKKCVEWTWQA 116
I++R KRM+GY+ L+ G D+ G+ T+ KVE +E G ++ E F++K EW +
Sbjct: 68 ILSRLKRMQGYDTLWLPGMDHAGIATQAKVEAKLREEGKSRYDLGREAFVEKTWEWKEEY 127
Query: 117 IEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRT 176
+ +R+Q+ ++G S D+ E T+D+ AV++ ++ Y+KGLIYR E+ + W P +T
Sbjct: 128 ADFIRQQWAKLGLSLDYSRERFTLDEGLSKAVREVFVKLYEKGLIYRGEYIINWDPVTKT 187
Query: 177 SLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVG 236
+L+ EV Y + +GY Y++K PLADG G I +ATTRPE M AV VHP+DERY+HL+G
Sbjct: 188 ALSDIEVIYKDVQGYFYHMKYPLADGDGAIEVATTRPETMLGDTAVAVHPEDERYQHLIG 247
Query: 237 KKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTM 296
K VKLPI RE+PI+AD+ VD FG+GAV D D R+NLP I+ +NEDGTM
Sbjct: 248 KMVKLPITGREIPIVADDYVDMEFGSGAVKITPAHDPNDFEIGNRHNLPRILVMNEDGTM 307
Query: 297 NENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQW 356
NE AG Y G+ E RK+I +DL++ G+L+K E+ H V H+ERS A +E QW
Sbjct: 308 NEKAGQYEGMDRFECRKQIVKDLQEQGVLFKIEEHVHSV-GHSERSG--AVVEPYLSTQW 364
Query: 357 FIRVKDFTDEIVKV---AKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVC 413
F+++K ++ +++ ++N+ P+ W E++ DW ISRQ +G P W
Sbjct: 365 FVKMKPLAEQAIELQTTENKVNFVPDRFEKTYLRWMENIR-DWCISRQLWWGHRIPAWYH 423
Query: 414 K-NGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHE 472
K G + E +D + DVLD W S++ P W
Sbjct: 424 KETGEVYVGHEAPQDID----------------NWKQDEDVLDTWFSSALWPFSTMGW-- 465
Query: 473 AIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGP 532
DEEA ++ + T G DII W IF+ + TG+ P+KD++I+G+V
Sbjct: 466 ---PDEEAPD-YKRYYSTDALVTGYDIIFFWVSRMIFQGLEFTGQPPFKDVLIHGLVRDA 521
Query: 533 DGRKMSKSYGNVVAPDEVIPKYGADALRLWTAL-APPGEDHPFKWETVDYNFRFLQKVWN 591
+G+KMSKS GN V P EVI KYGADALR + A + PG D F WE V+ + F K+WN
Sbjct: 522 EGQKMSKSLGNGVDPMEVIDKYGADALRFFLATGSSPGNDLRFYWEKVESTWNFGNKIWN 581
Query: 592 IYRFAERHIKDFDYEKYKDIEL----EPLDRWILSRLHRIIKFATEELERYRFNLITREL 647
RFA + + D Y +I+L D+WIL+RL I+ T ++ Y F + R L
Sbjct: 582 ASRFA---LMNMDGMSYDEIDLTGEKSIADQWILTRLQETIETVTRLIDAYEFGEVGRHL 638
Query: 648 MTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHA 707
FIW ++ D YIEM K LYG+DE +K + L +L M LL P +P ITEEI+
Sbjct: 639 YNFIWDDLCDWYIEMAKLPLYGEDEVAKKTTRSVLAYVLDQTMRLLHPLMPFITEEIWQH 698
Query: 708 MFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLE-H 766
+ + GE S+ + SWP E+ E+A EL + ++ +R + +P++ ++E H
Sbjct: 699 LPHE--GE-SITVASWPVKSEEFTFEQAMGDMELLKDIIRSVRNTRAELNVPMSKEIELH 755
Query: 767 VAIYALESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVP 826
+ ++ D L +E+ G IEK F L KP G +
Sbjct: 756 I---QAKNEDVLTQLER---GKHYIEK---FCNPSTLVMGTAIEKPEKSMSNVLSGVELY 806
Query: 827 RIVEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVMIK-KEVFSEGERVETA 881
+ L + E IAR KE K+E E++ + +L+ + + K E E ER + A
Sbjct: 807 LPLAGLLDLEEEIARLEKEENKLEKEVERVQKKLSNQGFLAKAPEKVIEEERKKEA 862
>sp|Q9ZCN6|SYV_RICPR VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437655|pir||B71675 valine--tRNA ligase (EC 6.1.1.9)
(valS) RP687 - Rickettsia prowazekii
>gi|3861224|emb|CAA15124.1| (AJ235272) VALYL-TRNA
SYNTHETASE (valS) [Rickettsia prowazekii]
Length = 814
Score = 518 bits (1321), Expect = e-146
Identities = 301/827 (36%), Positives = 454/827 (54%), Gaps = 43/827 (5%)
Query: 3 PKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPS-YAIDTPPPFTSGTLHLGHVLSHTWID 61
PK Y+ E E KWQ W E +IY Y + +K Y +DTPPP SG LH+GH+ S+T D
Sbjct: 5 PKHYNFTENEKKWQNIWQELQIYAYDPNISKAEIYIVDTPPPTVSGQLHIGHIYSYTQTD 64
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPE--EFLKKCVEWTWQAIEA 119
I R++RM G N+ +P GFD++GLPTE VEK+ I E EF+K C+E
Sbjct: 65 FIVRFQRMIGKNIFYPIGFDDNGLPTERLVEKQKQIKAYNMERDEFIKICLEVVKNEEAK 124
Query: 120 MRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLA 179
R F +I S DW LEY T+ + Q S L+ KG +YR P+ W T+LA
Sbjct: 125 FRSLFKQIALSVDWSLEYQTISPLSRKISQMSFLDLLHKGEVYRANQPILWDTVDGTALA 184
Query: 180 KAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVGKKV 239
+A++ ++ + YI G + IATTRPEL+PACVAVF HPDD RYKHL K
Sbjct: 185 QADIEDKQKISSMNYITFKTEQGD-QLTIATTRPELLPACVAVFYHPDDVRYKHLADKSA 243
Query: 240 KLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMN-E 298
P++ +VPILAD V + GTG V CT+GD+ DI W K +NLP+ I + GT+N
Sbjct: 244 ITPLFNEKVPILADPLVQQDKGTGLVMCCTFGDQTDITWWKSHNLPLKTIITKKGTINFP 303
Query: 299 NAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFI 358
+ GL ++EAR KI + L++ LL K+E+I V + ERS AP+E+L QWFI
Sbjct: 304 HKLDIDGLTIKEARTKIIDILKEQSLLTKQEEIIQTV-KCAERSG--APLEILTVTQWFI 360
Query: 359 RVKDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCK---- 414
+ + ++K E+NWYP++M +RL++W S+ WDW ISRQR FG PFP W K
Sbjct: 361 KTITHKEALLKRTNELNWYPKNMKMRLENWINSLSWDWCISRQRYFGVPFPIWYSKRIGE 420
Query: 415 NGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAI 474
G I+ A LPVDP D P E++P DV+D W SS++P + T I
Sbjct: 421 EGKILYADISQLPVDPLKDLP----IGYSKEEVDPDLDVMDTWATSSVSPQLST---YGI 473
Query: 475 KGDEEAKKWFEHN--FPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGP 532
D K H+ FP LRPQ +IIRTWAFYTI ++ PWK+I+++G
Sbjct: 474 SEDLAINK-VRHDKLFPMDLRPQAHEIIRTWAFYTILKSHLHQNILPWKNIMVSGWCLAE 532
Query: 533 DGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNI 592
D KMSKS GNV+ P++++ +YGAD +R W+A + G D + + + R + K+WN
Sbjct: 533 DRSKMSKSKGNVLVPEKLLERYGADVIRYWSANSKLGADTAYSEDVMKNGKRLVNKLWNA 592
Query: 593 YRFAERHIKDFDYEKYK----DIE---LEPLDRWILSRLHRIIKFATEELERYRFNLITR 645
+F H E K DI+ D+W++++L ++K AT L+ Y +
Sbjct: 593 AKFVSIHFDKLTSEDKKVSLFDIKEKITNEFDQWMINKLVALVKLATNALQNYEYANAIY 652
Query: 646 ELMTFIWHEVADDYIEMVKYRLYGD---DEESKLKAKVALYELLYNVMLLLAPFVPHITE 702
F W D+Y+E+ K R Y + + + + + + LY ++ ++ L APF+PHITE
Sbjct: 653 LTEKFFWSIFCDNYLEISKTRSYDEANKNPQGQYSSILTLYHIMQTLLKLFAPFMPHITE 712
Query: 703 EIYHAMFKDKIGEKSVHLL-SWPEYREDRIDEKAEKLG-ELARKVVSEMRKYKNSHGMPL 760
E+Y ++ + S+H+ +W Y + ++ + + G E +++ +RK+K + + +
Sbjct: 713 ELYQILY----NKNSIHMQGNWINYGD--LNYEIDVQGPEGLLEILDIVRKFKAEYNLSI 766
Query: 761 NAKLEHVAIYALESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERI 807
A ++ + + + +L +D+ + E+++ + Q++ I
Sbjct: 767 KAPIKLLEVSGIVLSTEL---VEDLKNVTSAEEIQFKAKDDQIKVNI 810
>pir||SYBSVS valine--tRNA ligase (EC 6.1.1.9) - Bacillus stearothermophilus
Length = 880
Score = 509 bits (1296), Expect = e-143
Identities = 327/886 (36%), Positives = 473/886 (52%), Gaps = 64/886 (7%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+P KYD +E ++WL+ K ++ D NK + I PPP +G LHLGH T D
Sbjct: 8 MPPKYDHRAVEAGRYEWWLKGKFFEATGDPNKRPFTIVIPPPNVTGKLHLGHAWDTTLQD 67
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEF---GITKDQ--PEEFLKKCVEWTWQA 116
II R KRM+GY+VL+ G D+ G+ T+ KVE++ G+++ E+FL++ +W +
Sbjct: 68 IITRMKRMQGYDVLWLPGMDHAGIATQAKVEEKLRQQGLSRYDLGREKFLEETWKWKEEY 127
Query: 117 IEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRT 176
+R Q+ ++G D+ E T+D+ AV++ + Y+KGLIYR E+ + W P +T
Sbjct: 128 AGHIRSQWAKLGLGLDYTRERFTLDEGLSKAVREVFVSLYRKGLIYRGEYIINWDPVTKT 187
Query: 177 SLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVG 236
+L+ EV Y E +G LY+++ PLADGSG+I +ATTRPE M AV VHPDDERYKHL+G
Sbjct: 188 ALSDIEVVYKEVKGALYHMRYPLADGSGFIEVATTRPETMLGDTAVAVHPDDERYKHLIG 247
Query: 237 KKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTM 296
K VKLPI RE+PI+ADE VD FG+GAV D D R+NLP I+ +NEDGTM
Sbjct: 248 KMVKLPIVGREIPIIADEYVDMEFGSGAVKITPAHDPNDFEIGNRHNLPRILVMNEDGTM 307
Query: 297 NENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQW 356
NENA Y GL E RK+I DL++ G+L+K E+ H V H+ERS A IE QW
Sbjct: 308 NENAMQYQGLDRFECRKQIVRDLQEQGVLFKIEEHVHSV-GHSERSG--AVIEPYLSTQW 364
Query: 357 FIRVKDFTDEIVKVAK---EINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVC 413
F+++K + +K+ + ++ + PE W E++ DW ISRQ +G P W
Sbjct: 365 FVKMKPLAEAAIKLQQTDGKVQFVPERFEKTYLHWLENIR-DWCISRQLWWGHRIPAWYH 423
Query: 414 K-NGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHE 472
K G I E ++ +++ P DVLD W S++ P W +
Sbjct: 424 KETGEIYVDHEPPKDIE-NWEQDP---------------DVLDTWFSSALWPFSTMGWPD 467
Query: 473 AIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGP 532
D ++ +PT + G DII W IF+ + TGK+P+KD++I+G+V
Sbjct: 468 TDSPD------YKRYYPTDVLVTGYDIIFFWVSRMIFQGLEFTGKRPFKDVLIHGLVRDA 521
Query: 533 DGRKMSKSYGNVVAPDEVIPKYGADALRLWTAL-APPGEDHPFKWETVDYNFRFLQKVWN 591
GRKMSKS GN V P +VI +YGADALR + A + PG+D F E V+ + F K+WN
Sbjct: 522 QGRKMSKSLGNGVDPMDVIDQYGADALRYFLATGSSPGQDLRFSTEKVEATWNFANKIWN 581
Query: 592 IYRFAERHIKDFDYEKYK-DIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTF 650
RFA ++ YE+ E D WIL+RL+ I+ T+ E+Y F R L F
Sbjct: 582 ASRFALMNMGGMTYEELDLSGEKTVADHWILTRLNETIETVTKLAEKYEFGERGRTLYNF 641
Query: 651 IWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFK 710
IW ++ D YIEM K LYGDDE +K + L +L N M LL PF+P ITEEI+ +
Sbjct: 642 IWDDLCDWYIEMAKLPLYGDDEAAKKTTRSVLAYVLDNTMRLLHPFMPFITEEIWQNLPH 701
Query: 711 DKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMP--------LNA 762
+ GE S+ + WP+ R + +E+A + + ++ +R + P +
Sbjct: 702 E--GE-SITVAPWPQVRPELSNEEAAEEMRMLVDIIRAVRNVRAEVNTPPSKPIALYIKT 758
Query: 763 KLEHVAIYALESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYG 822
K EHV L++ L+ N +L I P ++ + V + I P
Sbjct: 759 KDEHVRAALLKNRAYLERF-------CNPSELLIDTNVPAPDKAMTAVVTGAELIMP--- 808
Query: 823 KLVPRIVEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVMIK 868
+E L N E I R KE K E++ + +L E + K
Sbjct: 809 ------LEGLINIEEEIKRLEKELDKWNKEVERVEKKLANEGFLAK 848
>sp|P11931|SYV_BACST VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|143797|gb|AAA22879.1| (M16318) valyl-tRNA synthetase
[Bacillus stearothermophilus]
Length = 880
Score = 506 bits (1289), Expect = e-142
Identities = 326/886 (36%), Positives = 472/886 (52%), Gaps = 64/886 (7%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+P KYD +E ++WL+ K ++ D NK + I PPP +G LHLGH T D
Sbjct: 8 MPPKYDHRAVEAGRYEWWLKGKFFEATGDPNKRPFTIVIPPPNVTGKLHLGHAWDTTLQD 67
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEF---GITKDQ--PEEFLKKCVEWTWQA 116
II R KRM+GY+VL+ G D+ G+ T+ KVE++ G+++ E+FL++ +W +
Sbjct: 68 IITRMKRMQGYDVLWLPGMDHAGIATQAKVEEKLRQQGLSRYDLGREKFLEETWKWKEEY 127
Query: 117 IEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRT 176
+R Q+ ++G D+ E T+D+ AV++ + Y+KGLIYR E+ + W P +T
Sbjct: 128 AGHIRSQWAKLGLGLDYTRERFTLDEGLSKAVREVFVSLYRKGLIYRGEYIINWDPVTKT 187
Query: 177 SLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVG 236
+L+ EV Y E +G LY+++ PLADGSG+I +ATTRPE M AV VHPDDERYKHL+G
Sbjct: 188 ALSDIEVVYKEVKGALYHMRYPLADGSGFIEVATTRPETMLGDTAVAVHPDDERYKHLIG 247
Query: 237 KKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTM 296
K VKLPI RE+PI+ADE VD FG+GAV D D R+NLP I+ +NEDGTM
Sbjct: 248 KMVKLPIVGREIPIIADEYVDMEFGSGAVKITPAHDPNDFEIGNRHNLPRILVMNEDGTM 307
Query: 297 NENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQW 356
NENA Y GL E RK+I DL++ G+L+K E+ H V H+ERS A IE QW
Sbjct: 308 NENAMQYQGLDRFECRKQIVRDLQEQGVLFKIEEHVHSV-GHSERSG--AVIEPYLSTQW 364
Query: 357 FIRVKDFTDEIVKVAK---EINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVC 413
F+++K + +K+ + ++ + PE W E++ W ISRQ +G P W
Sbjct: 365 FVKMKPLAEAAIKLQQTDGKVQFVPERFEKTYLHWLENIR-HWCISRQLWWGHRIPAWYH 423
Query: 414 K-NGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHE 472
K G I E ++ +++ P DVLD W S++ P W +
Sbjct: 424 KETGEIYVDHEPPKDIE-NWEQDP---------------DVLDTWFSSALWPFSTMGWPD 467
Query: 473 AIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGP 532
D ++ +PT + G DII W IF+ + TGK+P+KD++I+G+V
Sbjct: 468 TDSPD------YKRYYPTDVLVTGYDIIFFWVSRMIFQGLEFTGKRPFKDVLIHGLVRDA 521
Query: 533 DGRKMSKSYGNVVAPDEVIPKYGADALRLWTAL-APPGEDHPFKWETVDYNFRFLQKVWN 591
GRKMSKS GN V P +VI +YGADALR + A + PG+D F E V+ + F K+WN
Sbjct: 522 QGRKMSKSLGNGVDPMDVIDQYGADALRYFLATGSSPGQDLRFSTEKVEATWNFANKIWN 581
Query: 592 IYRFAERHIKDFDYEKYK-DIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTF 650
RFA ++ YE+ E D WIL+RL+ I+ T+ E+Y F R L F
Sbjct: 582 ASRFALMNMGGMTYEELDLSGEKTVADHWILTRLNETIETVTKLAEKYEFGERGRTLYNF 641
Query: 651 IWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFK 710
IW ++ D YIEM K LYGDDE +K + L +L N M LL PF+P ITEEI+ +
Sbjct: 642 IWDDLCDWYIEMAKLPLYGDDEAAKKTTRSVLAYVLDNTMRLLHPFMPFITEEIWQNLPH 701
Query: 711 DKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMP--------LNA 762
+ GE S+ + WP+ R + +E+A + + ++ +R + P +
Sbjct: 702 E--GE-SITVAPWPQVRPELSNEEAAEEMRMLVDIIRAVRNVRAEVNTPPSKPIALYIKT 758
Query: 763 KLEHVAIYALESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYG 822
K EHV L++ L+ N +L I P ++ + V + I P
Sbjct: 759 KDEHVRAALLKNRAYLERF-------CNPSELLIDTNVPAPDKAMTAVVTGAELIMP--- 808
Query: 823 KLVPRIVEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVMIK 868
+E L N E I R KE K E++ + +L E + K
Sbjct: 809 ------LEGLINIEEEIKRLEKELDKWNKEVERVEKKLANEGFLAK 848
>sp|Q05873|SYV_BACSU VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|541424|pir||S41420 valine--tRNA ligase (EC 6.1.1.9)
valS - Bacillus subtilis >gi|452309|emb|CAA54458.1|
(X77239) valyl-tRNA synthetase [Bacillus subtilis]
>gi|2635274|emb|CAB14769.1| (Z99118) valyl-tRNA
synthetase [Bacillus subtilis]
Length = 880
Score = 502 bits (1279), Expect = e-141
Identities = 317/882 (35%), Positives = 471/882 (52%), Gaps = 56/882 (6%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+P KYDP +E +WL+ K ++ D+ K Y++ PPP +G LHLGH T D
Sbjct: 8 MPTKYDPAAVEKDRYDFWLKGKFFEAGSDQTKEPYSVVIPPPNVTGRLHLGHAWDTTLQD 67
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVE---KEFGITKDQ--PEEFLKKCVEWTWQA 116
I+ R KRM+GY+VL+ G D+ G+ T+ KVE +E G ++ E+FL++ +W +
Sbjct: 68 IVTRMKRMQGYDVLWLPGMDHAGIATQAKVEAKLREEGKSRYDLGREKFLEETWKWKEEY 127
Query: 117 IEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRT 176
+ +R Q+ ++G D+ E T+D+ AV++ ++ Y+KGLIYR E+ + W P +T
Sbjct: 128 ADFIRSQWAKLGLGLDYSRERFTLDEGLSKAVREVFVKLYEKGLIYRGEYIINWDPATKT 187
Query: 177 SLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVG 236
+L+ EV Y + +G Y++ PLADGSG I IATTRPE M AV VHP+DERYKHL+G
Sbjct: 188 ALSDIEVIYKDVQGAFYHMSYPLADGSGSIEIATTRPETMLGDTAVAVHPEDERYKHLIG 247
Query: 237 KKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTM 296
K V LPI RE+PI+ D+ VD FG+GAV D D R+NL I+ +NEDGTM
Sbjct: 248 KTVILPIVNREIPIVGDDYVDMEFGSGAVKITPAHDPNDFELGNRHNLERILVMNEDGTM 307
Query: 297 NENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQW 356
NENA Y G+ E RKK+ +DL++ G+L+K E H V H+ERS A +E QW
Sbjct: 308 NENALQYQGMDRFECRKKLVKDLQEAGVLFKIEDHMHSV-GHSERSG--AVVEPYLSTQW 364
Query: 357 FIRVKDFTD---EIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVC 413
F+R++ D E+ K +++N+ P+ W E++ DW ISRQ +G P W
Sbjct: 365 FVRMQPLADAAIELEKKEEKVNFVPDRFEKTYLHWMENIR-DWCISRQLWWGHRIPAWYH 423
Query: 414 K-NGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHE 472
K G + E P E TDVLD W S++ P W +
Sbjct: 424 KETGELYVGLE----------------APEDSENWEQDTDVLDTWFSSALWPFSTMGWPD 467
Query: 473 AIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGP 532
D F+ +PT + G DII W IF+ + TG++P+KD++I+G++
Sbjct: 468 VTAED------FKRYYPTDVLVTGYDIIFFWVSRMIFQGIEFTGERPFKDVLIHGLIRDE 521
Query: 533 DGRKMSKSYGNVVAPDEVIPKYGADALRLWTAL-APPGEDHPFKWETVDYNFRFLQKVWN 591
GRKMSKS GN V P +VI KYGAD+LR + A + PG+D F +E V+ + F K+WN
Sbjct: 522 QGRKMSKSLGNGVDPMDVIDKYGADSLRYFLATGSSPGQDLRFSYEKVESTWNFANKIWN 581
Query: 592 IYRFAERHIKDFDYEKYK-DIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTF 650
RFA ++ Y++ E D+WIL+RL+ I+ T+ +RY F + R L F
Sbjct: 582 ASRFALMNMDGMTYDELDLSGEKSVADKWILTRLNETIEHVTQLADRYEFGEVGRHLYNF 641
Query: 651 IWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFK 710
IW + D YIEM K LYG+DE +K + L +L M LL PF+P +TEEI+ +
Sbjct: 642 IWDDFCDWYIEMAKLPLYGEDEAAKKTTRSILAYVLDQTMRLLHPFMPFLTEEIWQHL-- 699
Query: 711 DKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIY 770
GE S+ + WP + D +A +L +++ +R ++ P++ ++E +Y
Sbjct: 700 PHQGE-SITVSQWPAVVPEHTDTEAAADMKLLVELIRSVRNIRSEVNTPMSKQVE---LY 755
Query: 771 ALESYDD----LKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVP 826
S D+ L+ + N L+I +++ + V + I P
Sbjct: 756 IKTSTDEIASRLEANRSYVERFTNPSVLKIGTDIEAVDKAMTAVVSGAEVILP------- 808
Query: 827 RIVEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVMIK 868
+E L N E IAR KE K+ E++ + +L E M K
Sbjct: 809 --LEGLINIDEEIARLQKEFDKLTKEVERVQKKLGNEGFMKK 848
>pir||C72565 probable valyl-tRNA synthetase APE1805 - Aeropyrum pernix (strain
K1) >gi|5105495|dbj|BAA80808.1| (AP000062) 889aa long
hypothetical valyl-tRNA synthetase [Aeropyrum pernix]
Length = 889
Score = 482 bits (1227), Expect = e-135
Identities = 287/786 (36%), Positives = 423/786 (53%), Gaps = 42/786 (5%)
Query: 4 KKYDPNEIEPKWQKYWLEEKIYKYRLDENKPS--YAIDTPPPFTSGTLHLGHVLSHTWID 61
K++D E E K W E ++K LD + P IDTPPP+ SG H+G +T ID
Sbjct: 78 KRWDIGE-EEKLLSLWDAEDLHKSTLDPDDPREIVVIDTPPPYPSGKWHVGGAAHYTQID 136
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGI-------TKDQPEEFLKKCVEWTW 114
+IARY R++GYNV+ P D +GLP E++VEK +G+ T + E FL C E+
Sbjct: 137 MIARYFRLKGYNVVAPFYADRNGLPVEVQVEKTYGVVAHEMARTTEGRERFLALCSEFLD 196
Query: 115 QAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKC 174
+ + + + R+G D+ E T Y++ Q + ++ +++GLIY E PV WCP+C
Sbjct: 197 KVESEIVQLWRRLGCGFDYWRE-GTDSPRYRSMTQATFIDLWRRGLIYEAERPVRWCPRC 255
Query: 175 RTSLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHL 234
+T+LA+AE+ + E+E ++YY+K L + + +ATTRPEL+ C A+ HP+DERYK L
Sbjct: 256 KTTLAEAEIEHKEDEDFIYYVKYRLEEDGRDLVVATTRPELLAGCAALAYHPEDERYKGL 315
Query: 235 VGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDG 294
GK P+Y V I+ V +FGTG + C+YGDE+D+ +L + I+E+G
Sbjct: 316 AGKTAIAPLYGHRVKIVEHPAVKKDFGTGLMMICSYGDEEDVRLFLELDLKPKVLIDENG 375
Query: 295 TMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKK 354
MNENAGP AGL V+EAR++IAE LE+ GLL KKE+I H V C P++++ ++
Sbjct: 376 VMNENAGPIAGLPVKEARRRIAEILEREGLLVKKERIVHSV---PVCWRCKTPLQIIHRR 432
Query: 355 QWFIRVKDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCK 414
+ F+R DF D + + A ++++ PE +L DW +S+ DW ISR+R +GT P W C+
Sbjct: 433 ELFLRQLDFKDAVKQAAAKMDFKPEMHRKKLYDWIDSIKMDWPISRERFYGTEIPLWTCE 492
Query: 415 NGHIIPAREEDLPVDPRFDKPPVEKCPVCGAE---IEPVTDVLDCWVDSSITPLIITRWH 471
E P ++PP + CP CGA ++ T V D W DSSI+PL +TRW
Sbjct: 493 KCGAKLVPEPGRYYRPWAEEPPWDSCPRCGAPRRYLKGETRVFDTWFDSSISPLYVTRW- 551
Query: 472 EAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAG 531
K+++E LRPQG DIIRTW +Y+I R +LTGK ++ + I G+
Sbjct: 552 ------MWDKRFYERASRNVLRPQGQDIIRTWLYYSILRVLQLTGKPAFRWVRITGLGLD 605
Query: 532 PDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPP-GEDHPFKWETVDYNFRFLQKVW 590
P GR M KS GNV+ P+ +I KYG DA R W A+A G D+ F V F K+W
Sbjct: 606 PKGRPMHKSLGNVIDPEPIIAKYGGDAFRFWAAIAAKLGYDYRFDENKVKTGRNFATKLW 665
Query: 591 NIYRFAERHIKDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTF 650
N+ RF + K E++ + A EL+ Y + EL
Sbjct: 666 NLARFVSSFPRPEGSPLEKATEVDKAFLALADEYLEAADKAYGELDVYEPANLIYEL--- 722
Query: 651 IWHEVADDYIEMVKYRLYGDD----EESKLKAKVALYELLYNVMLLLAPFVPHITEEIYH 706
W A Y+E+VK R Y E + A L+ELL +++ L+P +P +T+ I+
Sbjct: 723 AWDIFASHYVELVKERSYNRSGLFTREEQEAAWATLHELLRRILVALSPIMPFVTDAIHR 782
Query: 707 AMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMR---KYKNSHGMPLNAK 763
++ SVH WP+ E+ +L AR +VS + K S G L
Sbjct: 783 RLY-----GSSVHRQRWPD--PLFTPEERRELAGKARLIVSVNKAVWNLKRSMGKKLYEP 835
Query: 764 LEHVAI 769
L+ V +
Sbjct: 836 LDTVEV 841
>pir||D72206 valine--tRNA ligase (EC 6.1.1.9) - Thermotoga maritima (strain
MSB8) >gi|4982399|gb|AAD36880.1|AE001819_3 (AE001819)
valyl-tRNA synthetase [Thermotoga maritima]
Length = 865
Score = 481 bits (1224), Expect = e-134
Identities = 313/897 (34%), Positives = 470/897 (51%), Gaps = 60/897 (6%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
L +Y+P EIE KW +YW E+ + + K ++I PPP +G +H+GH L+ T D
Sbjct: 4 LSTRYNPAEIETKWYRYWEEKGYFTPKGVGEK--FSIVIPPPNITGRIHMGHALNITLQD 61
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEF----GITKDQ--PEEFLKKCVEWTWQ 115
I+ RYKRM+GY+VL+ G D+ G+ T+ VEK G T+++ E+FL+ EW +
Sbjct: 62 IVVRYKRMKGYDVLWVPGEDHAGIATQNAVEKFLLQTQGKTREEIGREKFLEITWEWANK 121
Query: 116 AIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCR 175
+R+Q +G S DW E T+D+ AV+K +E Y+KGLIYR ++ V WCP+C+
Sbjct: 122 YRREIREQIKALGASVDWTRERFTLDEGLSRAVRKVFVELYRKGLIYRGKYIVNWCPRCK 181
Query: 176 TSLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLV 235
T L+ EV + E + LYY+K P+ D YI +ATTRPE M AV VHP+DERYK+ V
Sbjct: 182 TVLSDEEVEHKEHKSKLYYVKYPVKDSDEYIVVATTRPETMLGDTAVAVHPEDERYKNFV 241
Query: 236 GKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGT 295
GK + LP+ RE+P++AD+ VDP FGTGAV D D + +R+NLP+I +++
Sbjct: 242 GKTLILPLVGREIPVVADKYVDPKFGTGAVKVTPAHDPNDYLIAQRHNLPMIEIFDDNAR 301
Query: 296 MNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQ 355
+NEN G Y GL EAR+KI +DLE+ G L K E H V H R C IE Q
Sbjct: 302 INENGGKYKGLDRYEAREKIVKDLEEQGFLVKIEDYTHSV-GHCYR--CDTVIEPKLSDQ 358
Query: 356 WFIRVKDFTDEIVKVAK--EINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVC 413
WF+ K ++ + EI ++PE +W + DW ISRQ +G P W C
Sbjct: 359 WFVSTKPLAKRAIEAVENGEIRFFPERWTKVYLNWMYEIR-DWCISRQLWWGHRIPVWYC 417
Query: 414 KNGHIIPAREEDLPVDPRFDKPPVEKCPVCGA-EIEPVTDVLDCWVDSSITPLIITRWHE 472
++ + EED VEKC CG+ ++ DVLD W S++ P W E
Sbjct: 418 QDCGHLNVSEED-----------VEKCEKCGSTNLKQDEDVLDTWFSSALWPFSTLGWPE 466
Query: 473 AIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGP 532
E+ K++ +PT L G DII W I ++ KP+ + I+ +V
Sbjct: 467 E---TEDLKRY----YPTDLLVTGFDIIFFWVARMIMMGYEFMNDKPFSHVYIHQLVRDK 519
Query: 533 DGRKMSKSYGNVVAPDEVIPKYGADALRLWTA-LAPPGEDHPFKWETVDYNFRFLQKVWN 591
GRKMSKS GN + P EVI +YGAD +R A LA G D D +F K+WN
Sbjct: 520 YGRKMSKSLGNGIDPLEVIDEYGADPMRFTLAILAAQGRDIKLDPRYFDAYKKFANKIWN 579
Query: 592 IYRFAERHIKDFDYEKYKDIELEPL---DRWILSRLHRIIKFATEELERYRFNLITRELM 648
RF +++D YK++ LE L D+WIL+RL++ ++ T LE Y FN+ R +
Sbjct: 580 ATRFVLMNLED-----YKEVPLENLKTVDKWILTRLNKTVEEVTNALENYDFNIAARTIY 634
Query: 649 TFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAM 708
F W + D YIE K RL E + + L ++L + LL PF+P +TEE++
Sbjct: 635 NFFWDDFCDWYIEASKPRL---KTEERNLVQTVLVKVLDASLRLLHPFMPFLTEELWQ-- 689
Query: 709 FKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVA 768
K + +S+ + WPE + IDE AEK +V +R + +P + +++ V
Sbjct: 690 -KLPVAGESITIAKWPEIERELIDETAEKEFTRLMNMVRGVRNVRAEMNLPQSQRVK-VY 747
Query: 769 IYALESYDDLKLIEKDIAGTMNIEKLEIFKGEP--QLEERIVEVKPNYKRIG-----PRY 821
I E ++ +L+ K + NIE++ +P + E Y +G +
Sbjct: 748 IKGYEVTEEEELLLKTLG---NIEEVSFVNEKPPKTATAYVEEEIEAYVDLGGLIDFEKE 804
Query: 822 GKLVPRIVEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVMIKKEVFSEGERV 878
+ + +I+E ++ + + +++ VE + E VE TKE + +E + E +
Sbjct: 805 KERLKQIMEKIQKEIDRLEKKLANKDFVE-KAPEEVVEETKEKLNTNRERLARLESI 860
>sp|P36420|SYV_LACCA VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|541449|pir||A49856 valine--tRNA ligase (EC 6.1.1.9)
- Lactobacillus casei >gi|409360|gb|AAA57558.1| (L08854)
valyl-tRNA synthetase [Lactobacillus casei]
Length = 901
Score = 444 bits (1131), Expect = e-123
Identities = 275/782 (35%), Positives = 409/782 (52%), Gaps = 53/782 (6%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
L KYD +E + WL+E ++K D+ Y+I PPP +G LH+GH T D
Sbjct: 27 LAPKYDHKAVEEGRYQEWLDEDVFKPSGDKKAKPYSIVIPPPNVTGKLHMGHAWDTTLQD 86
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEF---GITKDQ--PEEFLKKCVEWTWQA 116
I+ R KR+ G++ L+ G D+ G+ T+ KVE + GI++ E+F++K EW +
Sbjct: 87 IVIRQKRIEGFDTLWLPGMDHAGIATQAKVEAKLRKEGISRYDLGREKFVQKVWEWKDEF 146
Query: 117 IEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRT 176
+ + Q+ ++G S D+ E T+D AV++ ++ Y +GLIYR E+ V W P+ RT
Sbjct: 147 AKTIHGQWAKMGLSLDYSRERFTLDKGLNQAVRRVFVDLYNQGLIYRGEYIVNWDPQART 206
Query: 177 SLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVG 236
+L+ EV + +++G Y++K P ADGSGYI IATTRPE M AV VHP DERYK +VG
Sbjct: 207 ALSDIEVIHKDDKGAFYHVKYPFADGSGYIEIATTRPETMMGDTAVAVHPGDERYKDMVG 266
Query: 237 KKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTM 296
++ LP+ R++PI+ D VDP FGTGAV D D R++L I +N+DGTM
Sbjct: 267 TELILPLANRKIPIIEDAYVDPEFGTGAVKITPAHDPNDFQVGNRHDLKRINTMNDDGTM 326
Query: 297 NENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQW 356
NENAG Y G+ EARK + DL+K GLL K E I H V H+ER+ +E QW
Sbjct: 327 NENAGKYQGMDRFEARKAMVADLDKAGLLLKVEPIVHSV-GHSERTG--VQVEARLSTQW 383
Query: 357 FIRVKDFTDEIVKVA----KEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWV 412
F+++K + +K K++ + PE W E++ DWVISRQ +G P W
Sbjct: 384 FVKMKPLAEAAIKAQQEPDKKVTFVPERFEHTYLQWMENIH-DWVISRQLWWGHQIPAWY 442
Query: 413 CKN------GHIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLI 466
K G P E+ DP DVLD W S++ P
Sbjct: 443 NKQTGETYVGMEAPKDIENWKQDP---------------------DVLDTWFSSALWPFS 481
Query: 467 ITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVIN 526
W D ++ +PT G DII W IF+ T ++P++ +I+
Sbjct: 482 TMGWPNTDAPD------YKRYYPTDTLVTGYDIIPFWVARMIFQGLHFTHQRPFQYTLIH 535
Query: 527 GMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALA--PPGEDHPFKWETVDYNFR 584
G++ GRKMSKS GN + P +VI KYGADALR W + PG+D F ++ V+ +
Sbjct: 536 GLMRDEQGRKMSKSLGNGIDPMDVIEKYGADALR-WFLITGNKPGQDTRFSYKQVEAAWN 594
Query: 585 FLQKVWNIYRFAERHIKDFDYEKYKDIELEPL-DRWILSRLHRIIKFATEELERYRFNLI 643
F+ K+WNI RF ++ D D + D L D+W+ ++L+ IK + R+ F +
Sbjct: 595 FINKIWNISRFVMMNLGDLDTPQQPDPSTFDLSDKWLFAQLNETIKQVMDLSARFEFGEM 654
Query: 644 TRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEE 703
R L F W+ +AD Y+EM K LYGDDE++K +V L L ++ LL P +P + +
Sbjct: 655 GRTLYNFTWNVLADWYVEMSKEVLYGDDEQAKAAKRVNLAYALDQILRLLHPVMPFVHGK 714
Query: 704 IYHAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAK 763
++ A+ KS+ S+P + A + ++ +R + G PL K
Sbjct: 715 LWLAL---PHTGKSIVTASYPVANTAFENADATSAMDAIIALIRGVRGIRKEAGAPLKTK 771
Query: 764 LE 765
++
Sbjct: 772 VD 773
>sp|Q55522|SYV_SYNY3 VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437643|pir||S76034 hypothetical protein -
Synechocystis sp. (strain PCC 6803)
>gi|1001391|dbj|BAA10881.1| (D64006) valyl-tRNA
synthetase [Synechocystis sp.]
Length = 910
Score = 427 bits (1087), Expect = e-118
Identities = 290/894 (32%), Positives = 446/894 (49%), Gaps = 67/894 (7%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
LP +Y+P E KWQ W E +K D Y + PPP +G+LH+GH + ID
Sbjct: 5 LPPQYEPTVTEAKWQTAWEESHAFKADPDRPGEPYCVVIPPPNVTGSLHMGHAFESSLID 64
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEF---GITKDQ--PEEFLKKCVEWTWQA 116
+ RY RMRG N L+ G D+ + + +E++ G T+D E+FL++ +W ++
Sbjct: 65 TLVRYHRMRGDNTLWLPGTDHASIAVQTILERQLKAEGKTRDDLGREKFLERAWQWKAES 124
Query: 117 IEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRT 176
+ Q R+G S DW E TMD+ AV+ + ++ Y++GLIYR + V WCP ++
Sbjct: 125 GSTIVNQLRRLGVSVDWTRERFTMDEGLSQAVKTAFIKLYEEGLIYRGNYLVNWCPASQS 184
Query: 177 SLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVG 236
+++ EV E +G+L+Y + PL DGSG + +ATTRPE M V V+P DERY +VG
Sbjct: 185 AVSDLEVENQEVDGHLWYFRYPLTDGSGELVVATTRPETMLGDTGVAVNPHDERYAAMVG 244
Query: 237 KKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTM 296
K + LP+ RE+PI+ADE VDP FGTG V D D V +R+NLP I +N+DG++
Sbjct: 245 KTITLPLVNREIPIVADELVDPEFGTGCVKVTPAHDPNDFVMGQRHNLPFINLLNKDGSL 304
Query: 297 NENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQW 356
NEN G +AG EARK + + LE G L K E +H V + +R P+E L QW
Sbjct: 305 NENGGDFAGQDRFEARKNVVQALEAQGFLVKIEPYRHSV-PYGDRGK--VPVEPLLSTQW 361
Query: 357 FIRVKDFTDEIVKVAKE---INWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVC 413
F++++ + E N+ PE +DW + DW ISRQ +G P W
Sbjct: 362 FVKIESLAQNALACLDEDNSPNFVPERWGKVYRDWLVKLK-DWCISRQLWWGHQIPAWYV 420
Query: 414 ---KNGHIIPAREEDLPVD--PRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIIT 468
NG I + D K E P + +P DVLD W S + P
Sbjct: 421 ISETNGAITDHTPFIVAYDEAEALAKAKAEYGPTVQLQQDP--DVLDTWFSSGLWPFSTM 478
Query: 469 RWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGM 528
W E + D+ AK +PT+ G DII W TG+ P+KD+ I+G+
Sbjct: 479 GWPE--QTDDLAK-----YYPTSTLVTGFDIIFFWVARMTMMAGHFTGQIPFKDVYIHGL 531
Query: 529 VAGPDGRKMSKSYGNVVAPDEVIPKYGADALR--LWTALAPPGEDHPFKW-------ETV 579
V +G+KMSKS N + P +I KYG DALR L +A G+D ++ E+V
Sbjct: 532 VRDENGKKMSKSANNGIDPLLLINKYGTDALRYTLIREVAGAGQDISLQYDRQKDESESV 591
Query: 580 DYNFRFLQKVWNIYRFAERHI-----KDFDYEKYKDIELEPLDRWILSRLHRIIKFATEE 634
+ + F K+WN RF ++ + +D+EL DRWILSRL+++I+ E+
Sbjct: 592 EASRNFANKLWNAARFVMMNLDGQTPQQLGLAPGEDLEL--ADRWILSRLNQVIQQTREQ 649
Query: 635 LERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDD-----EESKLKAKVALYELLYNV 689
+E Y + L FIW + D YIE+ K RL+ + + +L A+ L L ++
Sbjct: 650 IEDYGLGEAAKGLYEFIWGDFCDWYIELAKPRLWNKEGGDVGTQRQLVARQVLAHTLDSI 709
Query: 690 MLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEM 749
+ LL PF+PHITEE++ + + + + + L ++P + +D E L + + +
Sbjct: 710 IKLLHPFMPHITEELWQTLHQAE--GQFLALQAYPTVNQSLVDPALETQFALLIETLRTI 767
Query: 750 RKYKNSHGMPLNAKLEHVAIYALESYDD-----LKLIEKDIAGTMNIEKLEIFKG-EPQL 803
R + G+ A + + L+S +D L+L E I +E L++ P+
Sbjct: 768 RNLRAEAGIKPGAMVTVI----LQSENDQERQTLQLGETYIRDIGKVENLQVVSQLPPEQ 823
Query: 804 EERIVEVKPNYKRIGPRYGKL--------VPRIVEHLKNNAESIAREIKENGKV 849
+ I V + + P G + + + ++ + ESI + + G V
Sbjct: 824 TQAIAGVVDTIQVLIPLSGLVDLDILRNKIQKTLDKVTKEYESIEKRLSNPGFV 877
>sp|P26499|SYI_METTM ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|68525|pir||SYEXI isoleucine--tRNA ligase (EC
6.1.1.5) [validated] - Methanobacterium
thermoautotrophicum (strain Marburg)
>gi|149728|gb|AAA72950.1| (M59245) transfer RNA-Ile
synthetase [Methanobacterium thermoautotrophicum]
Length = 1045
Score = 420 bits (1068), Expect = e-116
Identities = 286/947 (30%), Positives = 461/947 (48%), Gaps = 100/947 (10%)
Query: 4 KKYDPNEIEPKWQKYWLEEKIYKY--RLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
K Y P+ IE K Q +W E IY+ L E P Y+ PP+ SG +HLG + D
Sbjct: 8 KSYKPHVIEEKVQSFWEERDIYERVKELREEGPRYSFLDGPPYCSGRIHLGTAWNKIMKD 67
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP-------EEFLKKCVEWTW 114
R+K MRG+NV G+D HGLP E KVE G+ + EEF++KC E+
Sbjct: 68 SYLRFKSMRGFNVRRQPGWDTHGLPIEHKVEGILGVRSKKDIEDKIGIEEFVRKCREFAM 127
Query: 115 QAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKC 174
+ M QF R+G DWD Y T D Y + +L ++K L+ R+ + WCP+C
Sbjct: 128 ENKAVMTSQFQRLGVWMDWDDPYVTFDPAYMESCWWTLKRAHEKDLLLRDLRVITWCPRC 187
Query: 175 RTSLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDE----- 229
T+LA AE+ Y E+E Y+K P++ G YI + TT P +PA +AV VHPD +
Sbjct: 188 ETALALAEIDYHEKEDPSIYVKFPVS-GDTYILVWTTTPWTLPANMAVAVHPDFDYAHTR 246
Query: 230 ---------------------------RYKHLVGKKVKLPIYEREVP--------ILADE 254
R L G + P+ E EVP ++ +
Sbjct: 247 LDGETYIMAEALVEKVLGEEAEIIKTVRGSELEGLTYRHPLDE-EVPCHRDMEHRVILGD 305
Query: 255 DVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKK 314
V GTG V+ +D K Y LPV ++E G E+AG Y GL V++A
Sbjct: 306 HVTLTEGTGCVHTAPGHGPEDFEIGKEYGLPVFCPVDEAGVFTEDAGKYRGLFVKDADSD 365
Query: 315 IAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEI 374
I +DL LL + E I H R+ C PI L +QWF+++ + D+++ +
Sbjct: 366 IIDDLRSKNLLLRAETISH---RYGFCWRCKTPIIYLATEQWFLKITEIKDKMLSELDRV 422
Query: 375 NWYPE-DMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNG---HIIPAREE--DLPV 428
W P R ++W E+ DW ISRQR +G P P WVC++ H++ + E +L V
Sbjct: 423 QWIPSWAGESRFRNWIENAR-DWTISRQRYWGIPIPIWVCEDCDSIHVVGSIGELRELAV 481
Query: 429 DPRFD-----KPPVEK----CPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEE 479
+ + + +P V++ C CG ++ DVLD W+DS + + + E
Sbjct: 482 EGQLEGDFIHRPHVDRIILECGRCGGRMKRTPDVLDVWIDSGVAGWAALHYP---REKEL 538
Query: 480 AKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSK 539
+WF ++F T +G D R W + + + P++ ++++G +GRKMSK
Sbjct: 539 FSEWFPYDFIT----EGHDQTRGWFYSQLGCGVIALDETPYRRVLMHGFTLDEEGRKMSK 594
Query: 540 SYGNVVAPDEVIPKYGADALRLWTALA-PPGEDHPFKWETVDYNFRFLQKVWNIYRFAER 598
S GNVV P++VI KYGAD LR + A P ED F W+ + + +WN+Y FA
Sbjct: 595 SLGNVVEPEDVIEKYGADVLRFYLLWANKPWEDLKFVWDELKNVNKMFNILWNVYVFATT 654
Query: 599 HIKDFDYEKYKDIELEPL-----DRWILSRLHRIIKFATEELERYRFNLITRELMTFIWH 653
++ D + D ELE L DRWI+SR++ + TE L+ F+ TRE+ FI
Sbjct: 655 YM-SLDRFQPGDHELEDLHFRDEDRWIISRVNSVALKVTEALDNLHFHRATREIHDFIVE 713
Query: 654 EVADDYIEMVKYRLYGD-DEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFK-- 710
+++ YI +++ R + + D+ KL A +LY L +++ L+P PH+ E+IY + +
Sbjct: 714 DLSRWYIRLIRSRTWIERDDPDKLAAYHSLYTALKTLIVTLSPIAPHVCEDIYQNLVRGA 773
Query: 711 DKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIY 770
+ +S+H+L W ED +D K E ++ R+++ + +++ L + + +
Sbjct: 774 EPDSPESIHMLDW-MVSEDAVDGKLEAEMDIVREIIEACARARDTARYKLRWPVREIVVV 832
Query: 771 A-----LESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLV 825
+ LE+ + LK + + A +I F + RI+ KPN +GP+ + +
Sbjct: 833 SEDDKVLEAAESLKGVIAEQANAKSIRTSTEFP-----DMRII-AKPNPATLGPKLRQDM 886
Query: 826 PRIVEHLKN-NAESIAREIKENGKVEFEIDGEKVELTKEDVMIKKEV 871
P ++ L+ + + ++ G ++DG + L +D++ + E+
Sbjct: 887 PPVMRKLEEADGAEVKAALESEGSFRVDLDGRIIVLEPDDIIFETEL 933
>sp|O27428|SYI_METTH ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437550|pir||H69049 isoleucine--tRNA ligase (EC
6.1.1.5) - Methanobacterium thermoautotrophicum (strain
Delta H) >gi|2622484|gb|AAB85852.1| (AE000900)
isoleucyl-tRNA synthetase [Methanobacterium
thermoautotrophicum]
Length = 1044
Score = 416 bits (1059), Expect = e-115
Identities = 280/947 (29%), Positives = 465/947 (48%), Gaps = 100/947 (10%)
Query: 4 KKYDPNEIEPKWQKYWLEEKIYKY--RLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
K Y P+ IE K Q +W E IY+ L E++P Y+ PP+ SG +HLG + D
Sbjct: 8 KSYRPHRIEEKVQSFWEERDIYERVKELREDRPRYSFLDGPPYCSGRIHLGTAWNKIMKD 67
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP-------EEFLKKCVEWTW 114
R+K M+G+NV G+D HGLP E KVE G+ + EEF+ KC E+
Sbjct: 68 TYLRFKSMKGFNVRRQPGWDTHGLPIEHKVEGLLGVRSKKDIEDKIGIEEFVNKCREFAV 127
Query: 115 QAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKC 174
+ M QF R+G DWD Y T D Y + +L ++K L+ R+ + WCP+C
Sbjct: 128 ENKAVMTGQFQRLGVWMDWDDPYVTFDPAYMESCWWTLKRAHEKDLLVRDLRVITWCPRC 187
Query: 175 RTSLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDE-RYKH 233
T+LA AE+ Y ++E Y+K P++ G +I + TT P +PA +AV VHPD E Y
Sbjct: 188 ETALALAEIDYHDKEDPSIYVKFPVS-GDTHILVWTTTPWTLPANMAVAVHPDFEYAYAR 246
Query: 234 LVG---------------------KKVK----------------LPIY-EREVPILADED 255
L G K+VK +P++ E E ++ +
Sbjct: 247 LDGETYIMAEALVEKVLGEEAEILKRVKGTELEGLTYRHPLDDEVPLHREIEHRVILGDH 306
Query: 256 VDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKI 315
V GTG V+ +D K+Y L VI ++E G E AG Y+G V++A + I
Sbjct: 307 VTLTEGTGCVHTAPGHGPEDFEIGKKYGLEVICPVDEAGIFTEEAGKYSGRFVKDADEDI 366
Query: 316 AEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEIN 375
DL GLL K I HR + C PI L +QWF+++ + D++++ +
Sbjct: 367 IADLRSKGLLLKAGTISHR---YGFCWRCKTPIIYLATEQWFLKITEIKDKMLRELDRVQ 423
Query: 376 WYPEDMF-LRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNG---HIIPAREE--DLPVD 429
W P R ++W E+ DW ISRQR +G P P W+C+ H++ + +E +L V+
Sbjct: 424 WVPSWAGESRFRNWIENAR-DWTISRQRYWGIPIPIWICEECDSIHVVGSIDELRELAVE 482
Query: 430 PRFD-----KPPVEK----CPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEA 480
+ +P V++ C CG ++ DVLD W+DS + + E
Sbjct: 483 GELEGDFIHRPHVDRIVLECGECGGRMKRTPDVLDVWIDSGVAGWAALHYPSET---ELF 539
Query: 481 KKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKS 540
++WF ++F T +G D R W + + + P++ ++++G +GRKMSKS
Sbjct: 540 REWFPYDFIT----EGHDQTRGWFYSQLGCGVIALDEVPYRRVLMHGFTLDEEGRKMSKS 595
Query: 541 YGNVVAPDEVIPKYGADALR---LWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAE 597
GNVV P++VI KYGAD LR LW P ED F W+ + + +WN+Y FA
Sbjct: 596 LGNVVEPEDVIEKYGADVLRFYLLWE--NKPWEDLKFVWDELRNVNKMFNILWNVYVFAT 653
Query: 598 RHIKDFDYE----KYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWH 653
++ ++ +D+ DRWILSR++ + TE +E F+ TRE+ FI
Sbjct: 654 TYMSLDRFQPGDHSAEDLSFRDEDRWILSRINSVALKVTEAIENLHFHRATREIHDFIVE 713
Query: 654 EVADDYIEMVKYRLYGD-DEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFK-- 710
+++ YI +++ R + + D+ KL A LY +L +++ L+P PH+ E+IY + +
Sbjct: 714 DLSRWYIRLIRSRTWIERDDPDKLAAYHTLYTVLKTLIVTLSPMAPHVCEDIYQNLVRGA 773
Query: 711 DKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIY 770
+ +S+H+L W E +D + E ++ R+++ + +++ L + + +
Sbjct: 774 EPDSPESIHMLDW-ILDEGAVDSQLEADMDIVREIIEACARARDTARYKLRWPVREMVVV 832
Query: 771 A-----LESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLV 825
+ L++ + LK + + A +I K + + + +PN +GPR + +
Sbjct: 833 SEDEGVLKAAESLKNVIAEQANAKSI------KTSTEFPDMKIIARPNPATLGPRLRQDI 886
Query: 826 PRIVEHLKN-NAESIAREIKENGKVEFEIDGEKVELTKEDVMIKKEV 871
P ++ L+ + ++ + +G+ E DG+K +LT ED++ + E+
Sbjct: 887 PLVMRELEGADGSAVKAALDSDGEFTVETDGKKFKLTSEDIVFETEL 933
>sp|Q9YF67|SYI_AERPE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437559|pir||E72729 probable isoleucyl-tRNA
synthetase APE0374 - Aeropyrum pernix (strain K1)
>gi|5104013|dbj|BAA79329.1| (AP000059) 1064aa long
hypothetical isoleucyl-tRNA synthetase [Aeropyrum
pernix]
Length = 1064
Score = 404 bits (1028), Expect = e-111
Identities = 285/950 (30%), Positives = 455/950 (47%), Gaps = 95/950 (10%)
Query: 4 KKYDPNEIEPKWQKYWLEEKIYKYRLDENKPS----YAIDTPPPFTSGTLHLGHVLSHTW 59
++YD +E + YW E IY+ +++ + Y +D PP ++ ++H+G +
Sbjct: 11 ERYDQFALESFVKSYWEENSIYRKVKEKSSRAPRKFYFLDGPPYASAKSIHIGTAWNKVV 70
Query: 60 IDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGIT-------KDQPEEFLKKCVEW 112
D++ R+ RM GYNV G+D HGLP E+K+E+ G+ K E F+ C +
Sbjct: 71 KDVVLRFYRMTGYNVWDKPGYDTHGLPIEVKIEQSLGVRVKREIEEKVGVENFIAACKRF 130
Query: 113 TWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCP 172
+ +EAM +QF IG DW+ Y T D Y + + + ++KGL+Y+ ++WCP
Sbjct: 131 VDENMEAMTRQFKEIGVFMDWENPYVTYRDEYIESGWWLVKKAWEKGLLYKGYRVLHWCP 190
Query: 173 KCRTSLAKAEVG-YVEEEGYLYYIKLPLADGSG-YIPIATTRPELMPACVAVFVHPDDER 230
+C T+LA EV Y E E Y+K P+ G Y+ + TT P +PA V HPD E
Sbjct: 191 RCETTLADYEVSEYRELEDPSIYVKFPVEGREGEYLLVWTTTPWTLPANAFVMAHPDMEY 250
Query: 231 YKHLVGK------KVKLPIYEREVPI---------------------------------- 250
K VG+ K +L RE +
Sbjct: 251 VKVRVGRDTLILAKARLDHVMREAGVSEYEVLEVLKGSQLEGLRYRHPLEDVVDAQRELS 310
Query: 251 ------LADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYA 304
+A E V P+ G+G V++ D +R PV+ ++E G M E AG Y+
Sbjct: 311 KWHKVVMAPEAVTPHEGSGLVHSAPGHGTIDYEIAQRIGAPVVSLVDERGFMTEAAGKYS 370
Query: 305 GLKVE-EARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDF 363
GL EA K I EDL G L+ I HR + C P+ L QWF+ V
Sbjct: 371 GLYFRGEANKAIVEDLRARGALFHAATIVHR---YPVCWRCKTPLLLRATTQWFVAVTRL 427
Query: 364 TDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKN---GHIIP 420
+++++ A+++ W P R + + DWVISRQR +G P P W C + H++
Sbjct: 428 KNQLMREAEKVEWQPGWAKTRFMNMLRELR-DWVISRQRYWGIPLPVWRCSSCGYEHVVG 486
Query: 421 AREEDLPVDPR----FDKPPVE----KCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHE 472
+ EE + R +P V+ KCP CG ++ V DVLD W DS I ++
Sbjct: 487 SVEELESMGGRRPENLHRPWVDRVELKCPRCGGSMKRVPDVLDVWFDSGIA------FYA 540
Query: 473 AIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLT-GKKPWKDIVINGMVAG 531
++ + + W E P +G D IR W F+++ R+ + G+ P++ ++++G
Sbjct: 541 SLGYPRDRETW-ERLKPVDFIVEGHDQIRGW-FFSLLRSGVIGFGETPYRRVLVHGFALD 598
Query: 532 PDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWN 591
GR+M KS GN V +E+I K D +R W ED F W+ +D R +WN
Sbjct: 599 EQGREMHKSLGNYVDFEELIAKVPRDVVRFWVLQNTVWEDLRFSWKGLDLMRRDFNVIWN 658
Query: 592 IYRFAERH--IKDFDYEKYK----DIELEPLDRWILSRLHRIIKFATEELERYRFNLITR 645
+Y FA + + FD + + LE DRWILSRL + + +E R + R
Sbjct: 659 VYAFASIYMGLDRFDPRRTSLSSVEDSLEVEDRWILSRLASLKRRYLTAMEDLRIHDAAR 718
Query: 646 ELMTFIWHEVADDYIEMVKYRLYGD-DEESKLKAKVALYELLYNVMLLLAPFVPHITEEI 704
L +FI +V+ Y+ +++ R++ + D SK A LY++L+ +L+ AP +P+ E +
Sbjct: 719 ALRSFIIEDVSHWYLRIIRRRVWEEVDTPSKRAAYATLYKVLWEWLLMAAPLIPYTAEYL 778
Query: 705 YHAMFK--DKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNA 762
Y +F+ ++ E+S+H+L PE + ID E+ E AR V+ + +N G+ L
Sbjct: 779 YIKVFREAEERPEESIHMLDMPEPEDHLIDSTLEEDMEKARMVLEAILSARNEAGLKLRR 838
Query: 763 KLEHVAIYALES--YDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPR 820
+ V I A L+ +E I N +++E RI V+P+Y R+GP+
Sbjct: 839 PVRRVIIAASNPGVEGSLRRLEGLIRLMANAKEIEFAPASALEATRIYRVEPDYGRLGPK 898
Query: 821 YGKLVPRIVEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVMIKKE 870
Y + +P+++ ++ I R + E G E E +G V+LT EDV +K E
Sbjct: 899 YKRDMPKVLRLIEEKGGEIGRVLAEKGVYEGEYEGLPVKLTLEDVSLKAE 948
>sp|Q9XDB4|SYI_FERPE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|4836216|gb|AAD30388.1|AF096862_2 (AF096862)
isoleucyl-tRNA synthase [Fervidobacterium pennivorans]
Length = 897
Score = 400 bits (1017), Expect = e-110
Identities = 258/786 (32%), Positives = 385/786 (48%), Gaps = 85/786 (10%)
Query: 12 EPKWQKYWLEEKIYKYRLDE--NKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRM 69
EP+ K+W E++IYK L+ N P+Y + PP+ +G +HLG ++ D + RYK M
Sbjct: 9 EPEMLKFWEEKEIYKKTLETRANAPTYLLHDGPPYANGDIHLGTAMNKILKDFVTRYKTM 68
Query: 70 RGYNVLFPQGFDNHGLPTELKVEKEFG--ITKDQPEEFLKKCVEWTWQAIEAMRKQFIRI 127
RGY V F G+D HGLP E +V G K P E K C E+ + ++ R++F R+
Sbjct: 69 RGYRVPFVPGWDTHGLPIEHRVTTSLGEEAKKKSPAEIRKLCKEFALKYVDIQREEFKRL 128
Query: 128 GYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVGYVE 187
G DW+ Y T+D Y+ + + G +YR PVYWCP CRT+LA+AE+ Y +
Sbjct: 129 GVKGDWEHPYITLDPDYEYHILDVFKTLVENGNVYRGNKPVYWCPTCRTALAEAEIEYHD 188
Query: 188 EEGYLYYIKLPLAD-GSGYIPIATTRPELMPACVAVFVHPD--------DERY------- 231
E Y+K + D YI I TT P +PA VA+ +HPD DE Y
Sbjct: 189 HESPSIYVKFQMVDKPDTYIVIWTTTPWTIPANVAIALHPDYTYVKIKVDEEYWIVAEGL 248
Query: 232 --------------------KHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYG 271
K L GK K P+Y+R ++ + V GTG V+
Sbjct: 249 LQKFAADVGIDFEVVEKFVGKELEGKLTKHPLYDRTSVVVLADYVTLEDGTGCVHTAPGH 308
Query: 272 DEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKI 331
E+D +YNLPV+ ++++G + AG Y GLK+ +A K I EDL+ G L K KI
Sbjct: 309 GEEDYQTGLKYNLPVLSPVDDEGRFTKEAGKYEGLKIWDANKVIVEDLKNNGSLIKAGKI 368
Query: 332 KHRVLRHTERSSCMAPIELLPKKQWFIRV--KDFTDEIVKVAKEINWYPEDMFLRLKDWA 389
H H R C P+ QWFI V + ++++ K++ WYP R+
Sbjct: 369 SHS-YPHCWR--CKGPVMFRATPQWFISVDKNNLRGKVLEEIKKVKWYPAWGETRITAMV 425
Query: 390 ESMDWDWVISRQRVFGTPFPFWVCKN--------------GHIIPAREED--LPVDPRFD 433
+ DW ISRQRV+G P P CK+ +I+ + D +D
Sbjct: 426 QERP-DWTISRQRVWGVPIPAVKCKDCGEVTLEPKVIEHFANIVKEKGTDAWFELDVNEL 484
Query: 434 KPPVEKCPVCGAE-IEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTAL 492
P KCP CG++ E D LD W+DS + W I+ E FP L
Sbjct: 485 IPADFKCPACGSKNFEKTHDTLDVWMDSGCS------WEAVIRSKGE-------RFPVDL 531
Query: 493 RPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIP 552
+G D R W +IF + G P+K +V +G + GRKMSKS GNV+ P E++
Sbjct: 532 YLEGDDQHRGWFQSSIFLSTAKAGTAPFKAVVTHGFIKDEQGRKMSKSLGNVIDPMEIVN 591
Query: 553 KYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDF---DYEKYK 609
KYGAD LRLW A ++ ++ +K+ N R+ ++ DF D Y+
Sbjct: 592 KYGADILRLWVASTDFFDNIRVGKNIIEQQVEVYRKLRNTLRYLLSNLYDFTEADLLPYE 651
Query: 610 DIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYG 669
+L PLD+W L RL + I+ T+ E + ++ + + + E++ Y++++K RLY
Sbjct: 652 --KLLPLDKWALGRLQKFIEQITQYYEGFEYSKVYNATVKYCTTELSAVYLDILKDRLYV 709
Query: 670 DDEES--KLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYR 727
+ ++S + A+ AL+ +L ++ +LAP +P EE Y + +SVHL WPE R
Sbjct: 710 EAKDSIYRRSAQTALHYILEALIKILAPIIPFTAEEAYQESHLKRY--ESVHLEYWPEVR 767
Query: 728 EDRIDE 733
++ IDE
Sbjct: 768 KEFIDE 773
>emb|CAB75396.1| (AL139298) valyl tRNA synthetase [Streptomyces coelicolor A3(2)]
Length = 874
Score = 397 bits (1009), Expect = e-109
Identities = 254/769 (33%), Positives = 382/769 (49%), Gaps = 48/769 (6%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
LP +Y P E+E + + W+E ++ +KP Y + PPP +G+LHLGH HT ID
Sbjct: 16 LPTQYTPAEVEGQLYERWVERGYFEADAKSDKPPYTVVIPPPNVTGSLHLGHAFEHTLID 75
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP-----EEFLKKCVEWTWQA 116
+ R KRM+GY L+ G D+ G+ T+ VE+E G E F+++ +W ++
Sbjct: 76 ALTRRKRMQGYETLWQPGMDHAGIATQNVVERELGKEGKSRHDLGREAFVERVWQWKSES 135
Query: 117 IEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRT 176
+ Q R+G + W E TMD+ AVQ Y LIYR E + WCP+C T
Sbjct: 136 GGQISGQMRRLGDAVAWSRERFTMDEGLSQAVQTIFKRLYDDELIYRAERIINWCPRCLT 195
Query: 177 SLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVG 236
+++ EV Y +++G L + + +G I +ATTR E M AV VHP+DERYKHLVG
Sbjct: 196 AISDIEVEYQDDDGEL--VSMKYGEGDETIVVATTRAETMLGDTAVAVHPEDERYKHLVG 253
Query: 237 KKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTM 296
K +KLP+ +R +P++ADE VDP FGTGAV D D +R+ LP I ++E +
Sbjct: 254 KLIKLPLTDRSIPVVADEHVDPEFGTGAVKVTPAHDPNDFEIGQRHGLPAIAVMDEHAVI 313
Query: 297 NENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQW 356
+ GP+ G EAR I L G + +++ + H R C IE QW
Sbjct: 314 TAH-GPFQGQDRLEARSAIVAALRAEGRIVAEKRPYVHSVGHCSR--CKTTIEPRLSMQW 370
Query: 357 FIRVKDFTDEIVKVAKE--INWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCK 414
+++V ++ + +P++M R DW +++ DW ISRQ +G P W
Sbjct: 371 WVKVGPLAKAAGDAVRDGKVKIHPQEMEKRYFDWVDNLH-DWCISRQLWWGHRIPVWYGP 429
Query: 415 NGHII---PAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWH 471
G ++ P E P G +DVLD W S + P W
Sbjct: 430 EGEVVCVGPGEE-----------------PPSGEGWYQDSDVLDTWFSSGLWPFSTLGWP 472
Query: 472 EAIKGDEEAKKWFEHNFPTALRPQGTDIIRTW-AFYTIFRTFKLTGKKPWKDIVINGMVA 530
E E K+ +P ++ G DI+ W A +F + + G P+ I ++GMV
Sbjct: 473 EQ---TESLAKF----YPNSVLVTGYDILFFWVARMMMFGLYAMDGTPPFHTIALHGMVR 525
Query: 531 GPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTAL-APPGEDHPFKWETVDYNFRFLQKV 589
+G+KMSKS+GNVV P + + KYG+DALR A A PG D P + V + F K+
Sbjct: 526 DQNGKKMSKSFGNVVNPLDWMDKYGSDALRFTLARGANPGVDVPIGEDWVQGSRNFANKI 585
Query: 590 WNIYRFAERHIKDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMT 649
WN RFA + + + DRWILSRL+ ++ E Y+F ++ L
Sbjct: 586 WNATRFALMNGATVEGPLPDASRMSSTDRWILSRLNSVVAEVDAYYEDYQFAKLSDALFH 645
Query: 650 FIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMF 709
F W EV D Y+E+ K E +++ +V L E+L + LL P VP +TE ++ +
Sbjct: 646 FAWDEVFDWYVELSKTTFQAGGEAAEVSKRV-LGEVLDVTLRLLHPVVPFVTETLWTTL- 703
Query: 710 KDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGM 758
G +SV + WP R D AE+ E + V++E+R+++ G+
Sbjct: 704 ---TGGESVVIAEWPTDSGFR-DAGAEREIETVQSVITEVRRFRADQGL 748
>sp|P46213|SYI_THEMA ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437563|pir||B72263 isoleucine--tRNA ligase (EC
6.1.1.5) - Thermotoga maritima (strain MSB8)
>gi|4981921|gb|AAD36431.1|AE001790_3 (AE001790)
isoleucyl-tRNA synthetase [Thermotoga maritima]
Length = 919
Score = 395 bits (1005), Expect = e-109
Identities = 273/885 (30%), Positives = 434/885 (48%), Gaps = 99/885 (11%)
Query: 3 PKKYDPNEIEPKWQKYWLEEKIYKYRLDENK--PSYAIDTPPPFTSGTLHLGHVLSHTWI 60
P K + E + + W + +Y Y L++ K P + + PP+ +G +H+G L+
Sbjct: 15 PMKANLVNKEKVFLEEWEKMDLYNYVLEQRKGKPLFVLHDGPPYANGHIHIGTALNKILK 74
Query: 61 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFG--ITKDQPEEFLKKCVEWTWQAIE 118
DI+ +YK MRGY + G+D HGLP E +V +E G I + P E KKC E+ + ++
Sbjct: 75 DIVVKYKTMRGYRAPYVPGWDTHGLPIEHRVSQELGEKIKEMSPAEIRKKCEEFALRFVD 134
Query: 119 AMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSL 178
R++F R+G DW+ Y T+ Y+ + ++G +YR P+YWCP+CRT+L
Sbjct: 135 IQREEFKRLGVRGDWENPYITLKPDYEVKILDVFKTLVEQGNVYRSLKPIYWCPRCRTAL 194
Query: 179 AKAEVGYVEEEGYLYYIKL-PLADGSGYIPIATTRPELMPACVAVFVHPDDE-------- 229
A+AE+ Y + + Y+K D + +I I TT P +PA V + +HPD E
Sbjct: 195 AEAEIEYHDHKSPSIYVKFRSKEDPNFFIVIWTTTPWTLPANVGIALHPDYEYSVVKVGE 254
Query: 230 ----------------------------RYKHLVGKKVKLPIYE-REVPILADEDVDPNF 260
+ K L GK+ PI++ R ++ + V
Sbjct: 255 EKWVIATDLLDAFSKETGIDCSNVVEKIKGKDLEGKEFVHPIFDDRTSRVILADYVSLET 314
Query: 261 GTGAVYNCT-YGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDL 319
GTG V+ +G+E I +Y LP++ ++E+G E AG Y G+ +E+A + I EDL
Sbjct: 315 GTGCVHIAPGHGEEDYIYGHVQYGLPIVSPVDEEGRFTEEAGKYKGMFIEDANEVIIEDL 374
Query: 320 EKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRV--KDFTDEIVKVAKEINWY 377
++ G+L I H H R C P+ +QWFI V + ++++ ++ W
Sbjct: 375 KRKGILVHASSITHSY-PHCWR--CKGPVIFRATEQWFISVDHNNLRQKVLEEIDKVKWI 431
Query: 378 PEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKN-----------GHIIPAREEDL 426
PE R++ E DW ISRQRV+GTP P CK H + E++
Sbjct: 432 PEWGRNRIRSMVEERP-DWCISRQRVWGTPIPAVKCKECGEVVLDPKVIEHFMKIVEKE- 489
Query: 427 PVDPRFDKPPVEK------CPVCGAE-IEPVTDVLDCWVDSSITPLIITRWHEAIKGDEE 479
+ F+K E CP CG E + D LD W+DS + IT E
Sbjct: 490 GTNAWFEKEVEELIPEDFVCPKCGKRSFEKMLDTLDVWIDSGASFEYITTKRE------- 542
Query: 480 AKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSK 539
+H FP + +G+D R W +IF G P+K+++ +G + GRKMSK
Sbjct: 543 -----DHPFPLDMYLEGSDQHRGWFHSSIFLAVAKRGSAPYKEVLTHGFIKDEQGRKMSK 597
Query: 540 SYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERH 599
S GNVV P EV+ KYGA+ LRLW A + D V+ +K+ N +RF +
Sbjct: 598 SLGNVVDPMEVVEKYGAEILRLWLASSDYFNDIKISMRIVEQQTEVYRKIRNTFRFLLGN 657
Query: 600 IKDFDYE--KYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVAD 657
++DFD E + +L +DRW L RL IIK ATE + Y F+ + ++ + E++
Sbjct: 658 LEDFDPELDRVPHEKLLTIDRWALGRLQEIIKRATEYYDSYEFSKVYNLVVKYCTTELSS 717
Query: 658 DYIEMVKYRLYGDDEES--KLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGE 715
Y+++VK RLY + ++S + A+ ++E+L ++M +LAP + EE+Y + +
Sbjct: 718 LYLDVVKDRLYVEAKDSIYRRSAQTVMHEILISLMKILAPIMTFTMEEVYSHLHEKDRKY 777
Query: 716 KSVHLLSWPEYREDRIDEKA----EKLGELARKVVS--EMRKYKNSHGMPLNAKLEHVAI 769
K+V WPEYRE+ ID K EKL + V+ E ++ ++ G L+A+ +
Sbjct: 778 KTVQAEYWPEYREEFIDRKLMEDFEKLLSIREDVLKALEEKRQQDVIGHSLDAE-----V 832
Query: 770 YALESYDDLK-LIEK--DIAGTMNI-EKLEIFKGEPQLEERIVEV 810
+ D +K L+EK DI + I K+ + +L+ +VEV
Sbjct: 833 VLVPKNDTIKALLEKYRDILEELFIVSKVSLSDASGELKGELVEV 877
>sp|O58792|SYI_PYRHO ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437549|pir||F71100 isoleucine--tRNA ligase (EC
6.1.1.5) - Pyrococcus horikoshii
>gi|3257481|dbj|BAA30164.1| (AP000004) 1066aa long
hypothetical isoleucyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 1066
Score = 393 bits (998), Expect = e-108
Identities = 290/981 (29%), Positives = 470/981 (47%), Gaps = 142/981 (14%)
Query: 4 KKYDPNEIEPKWQKYWLEEKIYKY--RLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+ Y P ++E K +++W E IY+ L +N P Y PP+ SG +HLG + D
Sbjct: 8 RDYTPGKLEEKIEEFWKENNIYQKIKELRKNGPKYYFLDGPPYVSGAIHLGTAWNKIIKD 67
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGI-TKDQPEE------FLKKCVEWTW 114
+I R++ M+GYNV GFD HGLP E+KVE+ G+ TK + EE F+KKC E+
Sbjct: 68 MIIRFRTMQGYNVWRQPGFDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
Query: 115 QAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKC 174
++ M +QF +G DWD Y T+ + Y + +L + ++KGL+ +++ ++WCP+C
Sbjct: 128 NNLKIMTEQFKMLGIWMDWDDPYMTIKNEYIESAWFTLKKAWEKGLLEKDKRVLHWCPRC 187
Query: 175 RTSLAKAEVG--YVEEEGYLYYIKLPLADGSG-YIPIATTRPELMPACVAVFVHPD---- 227
T+LA+ EV Y + Y+K P+ Y+ I TT P +PA +AV HP+
Sbjct: 188 ETALAEHEVRGEYKLRKDPSIYVKFPIEGKENEYLLIWTTTPWTLPANLAVSAHPEYDYV 247
Query: 228 --------DERY----KHLVGKK-----VKLPIYE----------REVPILADED----- 255
E Y K LV K VK + E R + +L DE
Sbjct: 248 KVKVEFNGKEEYWILAKALVDKVLGEIGVKGEVIEEFKGRELEGLRYIHVLMDEYPRQKE 307
Query: 256 ----------------VDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNEN 299
V GTG V+ E+D K+Y LP+ +++ G E
Sbjct: 308 FREKYEWAHRIILADFVTLEEGTGLVHTAPGHGEEDFEVGKKYGLPIYSPVDDQGRYVE- 366
Query: 300 AGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIR 359
G + G+ V+EA +I E L++ G L K +I+H+ H R C P+ QWF++
Sbjct: 367 -GKWKGIYVKEADPQIIEHLKEKGYLVKAGEIEHKY-PHCWR--CKTPLIFRATDQWFLK 422
Query: 360 VKDFTDEIVKVAKE-INWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHI 418
V D I+K E + WYP+ + +R + DWVISRQR +G P P W ++G I
Sbjct: 423 VSKVKDRIIKENDEKVTWYPDWVKIRFDNGVRDSG-DWVISRQRYWGIPLPIWQSEDGEI 481
Query: 419 -----------------IPAREEDLPVDPRFDKPPVEK----------------CPVCGA 445
+ DLP +E+ V G
Sbjct: 482 YVVGSWRELVELAVAIEVNGERIDLPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGK 541
Query: 446 EIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAF 505
E+ V DV+D W DS I W A G K+ FE +P +G D + W +
Sbjct: 542 EMRRVKDVVDVWFDSG-----IASW--ASLGYPRNKELFEKLWPADFIVEGEDQVTKWFY 594
Query: 506 YTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTAL 565
+ P++ + ++G V G KMSKS GN++ P+EV+ K G D R +
Sbjct: 595 SQQAASVIAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVEKAGRDTFRFYMLW 654
Query: 566 AP-PGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDFDYE----KYKDIELEPLDRWI 620
A P E+ F W+ V+ R L +WN+Y + ++ +++ K +++ D+WI
Sbjct: 655 ATNPWENLKFSWKGVEQVRRMLNILWNVYVLSATYMSLDNFDPRNVKVEELAFREEDKWI 714
Query: 621 LSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGD-DEESKLKAK 679
LSR++ +I+ +E + TR L F+ +++ Y+ +++ RL+ + D+ KL A
Sbjct: 715 LSRVNSLIREVENGIETFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGDDPDKLAAY 774
Query: 680 VALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLG 739
L+++ ++ L+APF P+ITEEIY + + IG +SVH+L WP+ E +DE EK
Sbjct: 775 YTLWKVFDVLLRLMAPFTPYITEEIYQNLMRPFIGIESVHMLDWPKVDESAVDEDLEKEM 834
Query: 740 ELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESYDDL--KLIEK---DIAGTMNIEKL 794
E R++V + + L + + I E+ D+ K +E+ + +N +++
Sbjct: 835 EFIRRIVEAGSAARQKARIKLRYPVRKIII---ETQDETVKKAVERLNYILRDQLNAKEV 891
Query: 795 EIFKGEPQLEERIVEVKPNYKRIGPRY---GKLVPR-IVEHLKNNAESIAREIKENGKVE 850
I K ER + VKPN+ ++GP + +LV + I EH E+ E G+V+
Sbjct: 892 VIGK-----VERELTVKPNFAKVGPEFKGDSRLVAKWINEH--------GLELYEKGEVD 938
Query: 851 FEIDGEKVELTKEDVMIKKEV 871
EI+G+K LT+E +++++++
Sbjct: 939 VEIEGKKFHLTREHIIVEEKL 959
>sp|Q9V072|SYI_PYRAB ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437558|pir||H75139 isoleucyl-tRNA synthetase (iles)
PAB0616 - Pyrococcus abyssi (strain Orsay)
>gi|5458344|emb|CAB49833.1| (AJ248285) isoleucyl-tRNA
synthetase (ileS) [Pyrococcus abyssi]
Length = 1067
Score = 391 bits (994), Expect = e-107
Identities = 288/977 (29%), Positives = 467/977 (47%), Gaps = 134/977 (13%)
Query: 4 KKYDPNEIEPKWQKYWLEEKIYKY--RLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
++YDP ++E K +K+W E +IY+ L ++ P Y PP+ SG +HLG + D
Sbjct: 8 REYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKD 67
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGI-TKDQPEE------FLKKCVEWTW 114
+I R++ M+GYNV G+D HGLP E+KVE+ G+ TK + EE F+KKC E+
Sbjct: 68 MIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFAL 127
Query: 115 QAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKC 174
++ M +QF +G DWD Y T+ + Y + +L ++KGL+ +++ ++WCP+C
Sbjct: 128 NNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRC 187
Query: 175 RTSLAKAEVG--YVEEEGYLYYIKLPLADGSG-YIPIATTRPELMPACVAVFVHPD---- 227
T+LA+ EV Y + Y+K P+ Y+ I TT P +PA +AV HPD
Sbjct: 188 ETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYV 247
Query: 228 --------DERY----KHLVGKK-----VKLPIYE----------REVPILADED----- 255
E Y K LV K VK + E R V IL DE
Sbjct: 248 KVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKE 307
Query: 256 ----------------VDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNEN 299
V GTG V+ E+D ++Y LPV +++ G E
Sbjct: 308 FKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTE- 366
Query: 300 AGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIR 359
G + G+ V+EA KI E L + G L K +I+H+ H R C P+ QWF++
Sbjct: 367 -GKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKY-PHCWR--CKTPLIFRATDQWFLK 422
Query: 360 VKDFTDEIVKVAKE-INWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHI 418
+ D+I+K E + WYP+ + +R + DWVISRQR +G P P W ++G I
Sbjct: 423 ISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSG-DWVISRQRYWGIPLPIWQSEDGEI 481
Query: 419 I-------------------------PAREEDLPVDPR------FDKPPVEK--CPVCGA 445
+ EE L V +P V+ V G
Sbjct: 482 YVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGK 541
Query: 446 EIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAF 505
++ V DV+D W DS I W A G K+ FE +P +G D + W +
Sbjct: 542 DMRRVKDVVDVWFDSGIAS-----W--ASLGYPRNKELFEKLWPADFIVEGEDQVTKWFY 594
Query: 506 YTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTAL 565
+ P++ + ++G V G KMSKS GN++ P+EV+ + G D R +
Sbjct: 595 SQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLW 654
Query: 566 AP-PGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIK--DFDYEKYKDIEL--EPLDRWI 620
A P E+ F W+ V+ R L +WN+Y A ++ +FD K EL D+WI
Sbjct: 655 ATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWI 714
Query: 621 LSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEE-SKLKAK 679
LSR++ +I +E + TR L F+ +++ Y+ +++ RL+ + E+ KL A
Sbjct: 715 LSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAY 774
Query: 680 VALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLG 739
L+++ ++ LLAPF P+I EEIY + + +SVH+L WP+ E IDE+ E+
Sbjct: 775 YTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREM 834
Query: 740 ELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESYDD-----LKLIEKDIAGTMNIEKL 794
E R++V + + L + + I E+ D+ ++ + + + +N +++
Sbjct: 835 EFIRRIVEAGSAARQRAKIKLRYPVRRIII---ETEDETVKKAVERLNRILRDQLNAKEV 891
Query: 795 EIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKNNAESIAREIKENGKVEFEID 854
++ + ER + +KPN+ ++GP + I + + N RE+ E G++ EID
Sbjct: 892 KVGR-----VERELTIKPNFAKLGPEFKGDAKIIAKWINEN----GRELYEKGELTVEID 942
Query: 855 GEKVELTKEDVMIKKEV 871
G+ LT+E +++++++
Sbjct: 943 GKTFHLTREHIIVEEKL 959
>sp|P56000|SYV_HELPY VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437645|pir||A64664 valine--tRNA ligase (EC 6.1.1.9)
- Helicobacter pylori (strain 26695)
>gi|2314306|gb|AAD08195.1| (AE000621) valyl-tRNA
synthetase (valS) [Helicobacter pylori 26695]
Length = 874
Score = 389 bits (988), Expect = e-107
Identities = 267/814 (32%), Positives = 406/814 (49%), Gaps = 47/814 (5%)
Query: 3 PKKYDPNEIEPKWQKYWLEEKIYKY----RLDENKPSYAIDTPPPFTSGTLHLGHVLSHT 58
P Y P EIE K + ++ + E + + PPP +G LH+GH L+ +
Sbjct: 7 PTTYQPEEIEKKIYEICSHRGYFEIDGNEAIQEKNKRFCLMMPPPNVTGVLHIGHALTLS 66
Query: 59 WIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEF---GITKDQ--PEEFLKKCVEWT 113
DI+ARYKRM GY L+ G D+ G+ T+ VEK+ GI K+ EEF+KK EW
Sbjct: 67 LQDILARYKRMDGYKTLYQPGLDHAGIATQNVVEKQLLSQGIKKEDLGREEFIKKVWEWK 126
Query: 114 WQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPK 173
++ A+ +Q R+G SA + TMD + AV+ + L++Y+KGLI ++ + V WC K
Sbjct: 127 EKSGGAILEQMKRLGVSAAFSRTRFTMDKGLQRAVKLAFLKWYEKGLIIQDNYMVNWCTK 186
Query: 174 CRTSLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKH 233
+L+ EV Y E +G LYYI+ L + Y+ +ATTRPE + A+ V+P+DERYKH
Sbjct: 187 -DGALSDIEVEYEERKGALYYIRYYLENQKDYLVVATTRPETLFGDSALMVNPNDERYKH 245
Query: 234 LVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINED 293
LVG+K LP+ R +PI+ADE V+ FGTG V D D KR++L I +E
Sbjct: 246 LVGQKAILPLIHRTIPIIADEHVEMEFGTGCVKVTPGHDFNDYEVGKRHHLETIKIFDEK 305
Query: 294 GTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPK 353
G +N + G + L+ EAR K+ E L++ LL K E+ H+V H R C +E
Sbjct: 306 GILNAHCGEFENLERLEARDKVVERLKENALLEKIEEHTHQV-GHCYR--CHNVVEPYVS 362
Query: 354 KQWFIRVKDFTDEIVKVAKEI-NWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWV 412
KQWF++ + I K+ + + +YP + W + W ISRQ +G P +
Sbjct: 363 KQWFVKPEIAQSSIEKIQQGLARFYPSNWINNYNAWMRELR-PWCISRQLFWGHQIPVFT 421
Query: 413 CKNGHIIPAREEDLPVDPRFDKPPVEKCPVCGAE-IEPVTDVLDCWVDSSITPLIITRWH 471
C+N H + + L CP C +E +E DVLD W S + W
Sbjct: 422 CENNHQFVSLDTPL------------SCPTCKSETLEQDKDVLDTWFSSGLWAFSTLGWG 469
Query: 472 EAIKG--DEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMV 529
+ G +E K F +P G DI+ W +F + L G+ P+KDI ++ +V
Sbjct: 470 QEKSGLFNESDLKDF---YPNTTLITGFDILFFWVARMLFCSESLLGELPFKDIYLHALV 526
Query: 530 AGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTA-LAPPGEDHPFKWETVDYNFRFLQK 588
G KMSKS GNV+ P E+I KYGAD+LR A L G D ++ N F K
Sbjct: 527 RDEKGEKMSKSKGNVIDPLEMIEKYGADSLRFTLANLCATGRDIKLSTTHLENNKNFANK 586
Query: 589 VWNIYRFAERHIKDF-DYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITREL 647
++N + + + F D E+ + + PL R+ SRL+ K A L+ YRFN T L
Sbjct: 587 LFNAASYLKLKQESFKDKERLNEYQ-TPLGRYAKSRLNSATKEARNALDNYRFNDATTLL 645
Query: 648 MTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHA 707
F+W E D +IE K DE L +L + LL PF+P I+E +YH
Sbjct: 646 YRFLWGEFCDWFIEFSKVENEAIDE---------LGSVLKEALKLLHPFMPFISESLYHK 696
Query: 708 MFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHV 767
+ ++ E + ++ P ++ DEK E E+ + + +R+ K P L+
Sbjct: 697 LSNTEL-ENTESIMVMPYPKDLAQDEKLEHEFEVIKDCIVSLRRLKIMLETP-PIVLKEA 754
Query: 768 AIYALESYDDLKLIEKDIAGTMNIEKLEIFKGEP 801
++ E+ ++ + ++ +EK+ + +P
Sbjct: 755 SVGLREAIENTERLQTYAQKLARLEKVSVISSKP 788
>sp|Q58357|SYI_METJA ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|2129087|pir||C64418 isoleucine--tRNA ligase (EC
6.1.1.5) - Methanococcus jannaschii
>gi|1591614|gb|AAB98949.1| (U67538) isoleucyl-tRNA
synthetase (ileS) [Methanococcus jannaschii]
Length = 1039
Score = 386 bits (980), Expect = e-106
Identities = 314/985 (31%), Positives = 469/985 (46%), Gaps = 132/985 (13%)
Query: 4 KKYDP---NEIEPKWQKYWLEEKIY---KYRLDENKPSYAIDTPPPFTSGTLHLGHVLSH 57
KK +P E++ K +K+W E IY K + + NK Y +D PP + SG +HLG +
Sbjct: 2 KKVEPVNFRELDKKIKKFWEENDIYQKVKKKNERNKEFYFVDGPP-YCSGAIHLGTAWNK 60
Query: 58 TWIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGI-------TKDQPEEFLKKCV 110
D R+KRM+GYNVL G+D HGLP E+KVE EFGI TK ++F++KC
Sbjct: 61 IIKDTYLRFKRMQGYNVLDKAGWDMHGLPIEVKVENEFGIKNKKEIETKIGVKQFIEKCK 120
Query: 111 EWTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYW 170
E+ + E M KQF +G DW+ Y + Y +L ++KGL+ R+ VYW
Sbjct: 121 EFALKHKEIMEKQFKNLGVWLDWENAYMPITKEYMEIGWWTLKVAHEKGLLTRDLRVVYW 180
Query: 171 CPKCRTSLAKAEVGYVEEEGY--LYYIKLPLADGSG-YIPIATTRPELMPACVAVFVHPD 227
CP+C T+LA+ EV +E Y Y+K LA+ YI I TT P + A +AV VHPD
Sbjct: 181 CPRCETALAEHEVRGEYKEVYDPSVYVKFRLANEENTYIVIWTTTPWTLVANLAVTVHPD 240
Query: 228 -DERY-------------------------------------------KHLVGKKVKLPI 243
D Y K L G K P+
Sbjct: 241 YDYAYVEVEFDDKKEVWIIAEKLVEEVINKAKKFHNIKNYKIIKKVKGKELEGIKYIHPL 300
Query: 244 YEREV------------PILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAIN 291
E ++ E V GTG V+ E+D K+YNLP+ I+
Sbjct: 301 LEENERQKEFAELENAHTVILGEHVTLEGGTGLVHTAPGHGEEDFEVGKKYNLPIYSPID 360
Query: 292 EDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELL 351
++G E G + G+ V++A +I E L+ GLL KIKH H R C P+
Sbjct: 361 DEGKYVE--GKWKGVFVKDADAEIIETLKNKGLLVYAGKIKHSY-PHCWR--CKTPLLFR 415
Query: 352 PKKQWFIRVKDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFW 411
+QWF+ + D I++ AK + W P + R + + + DW ISRQR +G P P W
Sbjct: 416 ATEQWFLEISKIKDNIIEHAKTVQWIPHWVETRYINGVKFVG-DWNISRQRYWGIPIPVW 474
Query: 412 VCKN-------GHIIPAREEDLPVDP-----RFDKPPVEKCPV---CGAEIEPVTDVLDC 456
VC+ G + E+ + D KP V+K + CG E++ V DVLD
Sbjct: 475 VCEKCGKYIVVGSVEELEEKMINKDEVGEINDLHKPTVDKIKLRCECGGEMKRVPDVLDV 534
Query: 457 WVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTG 516
W DS + P A G +E KK +F T +G D + W + + +
Sbjct: 535 WFDSGLAPY-------ASIGVKELKK---ADFIT----EGHDQVTKWFYSQHALSAIVFN 580
Query: 517 KKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALA-PPGEDHPFK 575
P+K +++G G KMSKS GNVV PD+V+ KYGAD LR + A ED F
Sbjct: 581 DIPYKKCLMHGFTLDEHGDKMSKSLGNVVNPDDVVEKYGADLLRFYLLSANKVWEDLRFV 640
Query: 576 WETVDYNFRFLQKVWNIYRFAERHIKDFDY---EKYKDIELEPLDRWILSRLHRIIKFAT 632
W +D +WN Y FA ++ ++ EKY + L+ DRWI+SR++ + K A
Sbjct: 641 WSEMDDVLSLFNTLWNAYMFAVNYMVLDNFKPDEKYFEY-LKDEDRWIVSRINSVAKIAI 699
Query: 633 EELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGD-DEESKLKAKVALYELLYNVML 691
E LE F+ T L FI ++++ YI +++ R + + D+ KL A LY +L +
Sbjct: 700 ENLEVPYFHTYTWTLKDFILNDLSRWYIRLIRDRTWKEKDDADKLAAYQTLYYVLLKLAT 759
Query: 692 LLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRK 751
+LAP PH E IY + K + E+S+ ++ E E+ IDE+ E+ + R VV + +
Sbjct: 760 ILAPVAPHTAEAIYQNL-KTEDMEESI-FMNKIEVDEEFIDEELERDMAIVRDVVDAIYR 817
Query: 752 YKNSHGMPLNAKLEHVAIYALE----SYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERI 807
++ L L+ + I E + + + I K+ NI+ E+ +G +
Sbjct: 818 GRDRIKYTLRYPLKEITIAGGEEVKKAVERFEYIIKEQGNVKNIKFGEV-EGSKYI---- 872
Query: 808 VEVKPNYKRIGPRYGKLVPRIVEHL-KNNAESIAREIKENGKV--EFEIDGEKVELTKE- 863
+KPNY+ +G RY VP++VE L K +A+ + +KE + +EI E VE+ E
Sbjct: 873 --IKPNYRELGKRYRSEVPKVVEALNKADAKELMERLKEGAVILDGYEIKPEYVEIRLEI 930
Query: 864 DVMIKKEVFSEGE-RVETAVVDDIV 887
I FS+G + T + DD++
Sbjct: 931 PEHIAGVEFSKGTVFINTEITDDLI 955
>gi|11498241 isoleucyl-tRNA synthetase (ileS) [Archaeoglobus fulgidus]
>gi|3122898|sp|O29622|SYI_ARCFU ISOLEUCYL-TRNA
SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437551|pir||A69329 probable isoleucine--tRNA ligase
(EC 6.1.1.5) - Archaeoglobus fulgidus
>gi|2649988|gb|AAB90608.1| (AE001061) isoleucyl-tRNA
synthetase (ileS) [Archaeoglobus fulgidus]
Length = 1018
Score = 385 bits (979), Expect = e-105
Identities = 277/945 (29%), Positives = 441/945 (46%), Gaps = 101/945 (10%)
Query: 1 MLPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWI 60
MLP KY P ++E + K+W + IY+ ++ + PP+T+G +HLG +
Sbjct: 1 MLPAKYSPKDVESEIFKFWEDNDIYRKVKEKGGRKFYFVDGPPYTTGRIHLGTAWNKVLK 60
Query: 61 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCVEWTW 114
D I RYKRM G+ G+D HGLP E+KVE+E G + ++F+++C+ +
Sbjct: 61 DTILRYKRMMGFAPTDTPGWDMHGLPIEVKVEQELGFRTKRDIESFGIDKFIERCMNYAL 120
Query: 115 QAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKC 174
+AM +QF + DW+ Y T+ Y A ++ +++GL+ R++ V WC +C
Sbjct: 121 ANKDAMTEQFKSLAVWMDWENPYMTIKAEYMNAAWFAIKRAHERGLLERKKMVVNWCHRC 180
Query: 175 RTSLAKAEVGYVEEEGYLYYIKLPL-ADGSGYIPIATTRPELMPACVAVFVHPDDE--RY 231
T+LA AEV Y +EE Y+K P+ + YI I TT P +PA +AV VHP E ++
Sbjct: 181 ETALADAEVEYWDEEDPSIYVKFPVKGEKDTYIVIWTTTPWTLPANMAVAVHPSLEYAKF 240
Query: 232 KHLVGKKVKLPIYEREV-------------------------------PILADEDVDPNF 260
+ + KV+ I +E+ P+ + + N+
Sbjct: 241 RAVKDGKVEYLILAKELADSVLGKGDYDSWEVVETYLGEDLEGLEYEHPLADEVPLQKNW 300
Query: 261 -------------GTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLK 307
TG V+ +D L V +++ G E AG YAG
Sbjct: 301 KHQVFFADFVTAENTGCVHIAPGHGVEDYELGVEKGLEVFNPVDDRGVYTEEAGKYAGKH 360
Query: 308 VEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEI 367
V+EA I +DL + LL +E+I HR H R C PI +QWFI++ + DE+
Sbjct: 361 VKEANDDIIDDLYRKDLLLAEERIVHRY-GHCWR--CKTPIIYRATEQWFIKISELKDEM 417
Query: 368 VKVAKEINWYPEDM-FLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKN-------GHII 419
++ ++ W PE R KDW + DW ISRQR +G P P W+C+ G I
Sbjct: 418 LEEIDKVMWIPEWAGSARFKDWVSNAK-DWCISRQRYWGIPIPVWICEKCGEMKVVGSIN 476
Query: 420 PAR-EEDLPVD-PRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGD 477
E DL + P+ D V CG + V DV D W DS + W
Sbjct: 477 EIEWENDLDLHRPKIDA--VTFSCQCGGVMRRVPDVFDVWFDSGVAS-----WGSIAYPL 529
Query: 478 EEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKM 537
+ K FE +P +G D R W + + + K P+K ++++G GRKM
Sbjct: 530 RKDK--FEELWPADFITEGHDQTRGWFYSQLGTSVVCFDKAPYKAVLMHGFTLDEQGRKM 587
Query: 538 SKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAE 597
SKS GNVV P+EV+ + G D RL+ + P ED F WE R L VWN RFA
Sbjct: 588 SKSLGNVVEPEEVVGQIGVDGFRLYVLYSAPWEDLRFSWEEARNINRMLNVVWNAVRFAH 647
Query: 598 RHIKDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVAD 657
++ +Y + EL+ DRWILSRL IK A E +E Y+ + + R F + +
Sbjct: 648 TYMSLDNYSFGEKGELKIEDRWILSRLESFIKEANEAMEGYQVHRVVRAFFDFFVEDFSR 707
Query: 658 DYIEMVKYRLYGD-DEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKD-KIGE 715
YI++++ R++ + D SKL A ++ ++ + +APF P I E Y + K+ + GE
Sbjct: 708 WYIQIIRPRVWEERDSPSKLAAYYTMFRVIDRSLRAIAPFAPLIAEWFYQHVVKEFREGE 767
Query: 716 KSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESY 775
+S+ + + + ID + E ++A+++V +N L L + I ES
Sbjct: 768 ESIFMEEYSTAEVEMIDGELEAAMKVAKEIVEAAANARNKAKRKLRWPLRELVI---ESG 824
Query: 776 DD-----LKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVE 830
+ ++++E+ I N++++ + E+ +E+KPNYK IGP
Sbjct: 825 SEKVRKAVEMLEETILSQCNVKQVRVVDS----FEKEIEIKPNYKYIGPL---------- 870
Query: 831 HLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVMIKKEVFSEG 875
LK A A+ + ++ ++ + VEL + ++ EG
Sbjct: 871 -LKEKAGEFAKYVASLKEIPEKLVFDGVELDPKQAIVVDYRLPEG 914
>gb|AAF65673.1|AF208389_1 (AF208389) isoleucyl-tRNA synthetase [Methanosarcina barkeri]
Length = 1058
Score = 376 bits (955), Expect = e-103
Identities = 275/955 (28%), Positives = 440/955 (45%), Gaps = 98/955 (10%)
Query: 5 KYDPNEIEPKWQKYWLEEKIYKYRLDENKPS---YAIDTPPPFTSGTLHLGHVLSHTWID 61
KY+ +IE K + W + Y+ + K + +D PP +T+G +HLG + D
Sbjct: 8 KYNAEQIEKKITQLWKDSDAYRKTREHRKTGKRLFFVDGPP-YTTGHIHLGTAWNKIIKD 66
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCVEWTWQ 115
I RY M N+L G+D HGLP E+KVE G + E F++KC E+
Sbjct: 67 SILRYYSMNNRNILERPGWDMHGLPIEVKVEGVLGFKSKKDIESFGVENFIEKCKEFAIN 126
Query: 116 AIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCR 175
+ M +QF R+G W+ Y T+ D Y A +L + +K L+ + V WCP+C
Sbjct: 127 QKQEMTEQFQRLGVWMQWEAPYMTLKDDYIEAAWWTLKQASEKNLLDVGKRSVNWCPRCE 186
Query: 176 TSLAKAEVGYVEEEGYLYYIKLPL-ADGSGYIPIATTRPELMPACVAVFVHP-------- 226
T++A +EV Y E Y+K + + + +I I TT P +PA VAV VHP
Sbjct: 187 TAIADSEVEYAERTDPSIYVKFKIKGEENTFIVIWTTTPWTIPANVAVAVHPGFEYSKFR 246
Query: 227 ----------------------------DDERYKHLVGKKVKLPIYEREVPILADEDVDP 258
D E + ++G+ + YE V L +
Sbjct: 247 AIRQDGSDEILIAATDLIENVLRQGRYVDYEVLETMLGEDLTKLEYESPVGDLVPVQNEI 306
Query: 259 NFG-----------TGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLK 307
G TG V+ D +YNLP++ + +G E AG YAG
Sbjct: 307 KHGIYLADYVTAENTGCVHIAPGHGMDDFNVGVKYNLPILCPVGPNGAYTEEAGEYAGKN 366
Query: 308 VEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEI 367
V EA + EDL K L + + HR H R C PI L +QWF++V D D++
Sbjct: 367 VREANPIVIEDLRKRNRLLAEGTVTHRY-GHCWR--CKTPIIYLATEQWFLKVTDIKDKM 423
Query: 368 VKVAKEINWYPEDM-FLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNG---HIIPARE 423
++ ++WYPE R + W E DW ISRQR +G P P W CK +I +
Sbjct: 424 LEAIDAVDWYPEWAGSARFRTWVEGAR-DWCISRQRYWGMPIPVWKCKKCGKLEVIGTKA 482
Query: 424 EDLPV-----DPRFDKPPVEKCPV---CGAEIEPVTDVLDCWVDSSITPLIITRWHEAIK 475
E L D +P V+K + CG E + V DV D W DS++ ++ +
Sbjct: 483 ELLEKSGAGSDVELHRPYVDKLTIPCECGGEKKRVEDVFDVWFDSAVASWATLKFPQT-- 540
Query: 476 GDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGR 535
E+ +W+ +F T +G D R W + + + G+ P+K ++++G G+
Sbjct: 541 -REQFDEWWPADFIT----EGHDQTRGWFYSQLGASMVGFGRAPYKSVLMHGFTLDAGGK 595
Query: 536 KMSKSYGNVVAPDEVIPKYGADALRLWT-ALAPPGEDHPFKWETVDYNFRFLQKVWNIYR 594
KMSKS GNVV+P +VI KYGAD LR + + + P +D F E V+ R + +WN++R
Sbjct: 596 KMSKSLGNVVSPIDVIDKYGADTLRAYVLSSSAPWDDLKFNQEEVENVHRSINILWNVFR 655
Query: 595 FAERH--IKDFD-----YEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITREL 647
F + + +FD + KD L DRWILSR+ ++K E + Y + RE+
Sbjct: 656 FPLPYMALDNFDPLKVSLDSVKD-ALREEDRWILSRIQSVVKAVDEAMSGYFLHKAVREI 714
Query: 648 MTFIWHEVADDYIEMVKYRLYGD-DEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYH 706
+ F +++ YI++++ R + + D+ KL A LYE+ + L++PF+P++ EE+Y
Sbjct: 715 LEFTLEDLSRWYIQLIRPRTWTEADDPDKLAAYRVLYEVYVTLTKLISPFMPYLAEEMYQ 774
Query: 707 AMFK--DKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKL 764
+ + D +SVH+ WP+ E +D + E AR +V + G L +
Sbjct: 775 NLIRNVDPNALESVHMCDWPKVNEAYLDPELEAAMSTARSIVEAASNARQKAGRKLRWPV 834
Query: 765 EHVAIYALESYDDLKLIEK---DIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRY 821
+ + + ES D K +E+ + N + + + +E +EV P+ +IGP +
Sbjct: 835 SRIVV-SPESEDAAKAVERLRSVLMDQTNSKAIVLTPVGESWDELGLEVIPDPSKIGPVF 893
Query: 822 GKLVPRIVEHL-KNNAESIAREIKENGKVEFEIDGEKVELTKEDVMIKKEVFSEG 875
K +++ L K + ++ + E G+ E + + KE EG
Sbjct: 894 KKDAGKVIPALQKVDGFALKKAFAEAGEFELSLADRTTVTVTPGMANFKETLPEG 948
>sp|Q9ZK61|SYV_HELPJ VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437644|pir||E71852 valine--tRNA ligase (EC 6.1.1.9)
- Helicobacter pylori (strain J99)
>gi|4155674|gb|AAD06660.1| (AE001535) VALYL-TRNA
SYNTHETASE [Helicobacter pylori J99]
Length = 872
Score = 376 bits (954), Expect = e-103
Identities = 269/887 (30%), Positives = 425/887 (47%), Gaps = 63/887 (7%)
Query: 3 PKKYDPNEIEPKWQKYWLEEKIYKY----RLDENKPSYAIDTPPPFTSGTLHLGHVLSHT 58
P Y P EIE K + ++ ++ E + + PPP +G LH+GH L+ +
Sbjct: 5 PTTYQPEEIEKKIYEICSHRGYFEINGNEKIQEKGKRFCLMMPPPNVTGILHIGHALTLS 64
Query: 59 WIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEF---GITKDQ--PEEFLKKCVEWT 113
DI+ RYKRM GY L+ G D+ G+ T+ VEK+ G+ K+ E+F++K EW
Sbjct: 65 LQDILVRYKRMDGYKTLYQPGLDHAGIATQNVVEKQLLSQGVKKEDLGREKFIQKVWEWK 124
Query: 114 WQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPK 173
++ A+ +Q R+G S + TMD + AV+ + L++Y+KGLI ++ + V WC K
Sbjct: 125 EKSGGAILEQMKRLGVSTAFSRTRFTMDKGLQRAVKLAFLKWYEKGLIVQDNYMVNWCTK 184
Query: 174 CRTSLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKH 233
+L+ EV Y E +G LYYI+ L + Y+ +ATTRPE + A+ V+P+DERYKH
Sbjct: 185 -DGALSDIEVEYEERKGALYYIRYYLENQKDYLVVATTRPETLFGDSAIMVNPNDERYKH 243
Query: 234 LVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINED 293
LVG++V LP+ R +PI+AD V+ FGTG V D D KR++L I +E
Sbjct: 244 LVGQQVILPLINRTIPIIADAHVEMGFGTGCVKVTPGHDFNDYEVGKRHHLETIKIFDEK 303
Query: 294 GTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPK 353
G +N + G + L+ EAR K+ L++ LL K E+ H+V H R C +E
Sbjct: 304 GILNAHCGEFENLERLEARDKVVAALKENALLEKIEEHVHQV-GHCYR--CHNVVEPYVS 360
Query: 354 KQWFIRVKDFTDEIVKVAKEI-NWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWV 412
KQWF++ + I K+ + + +YP + W + W ISRQ +G P +
Sbjct: 361 KQWFVKPEIAQSSIEKIQQGLARFYPSNWINNYNAWMRELR-PWCISRQLFWGHQIPVFT 419
Query: 413 CKNGHIIPAREEDLPVDPRFDKPPVEKCPVCGAE-IEPVTDVLDCWVDSSITPLIITRWH 471
C+N H + + L CP C +E +E DVLD W S + W
Sbjct: 420 CENNHQFVSLDTPL------------SCPTCKSEKLEQDKDVLDTWFSSGLWAFSTLGWG 467
Query: 472 EAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAG 531
+ K D + + +P G DI+ W +F + L G+ P+KDI ++ +V
Sbjct: 468 QE-KSDLFNESDLKDFYPNTTLITGFDILFFWVARMLFCSESLLGELPFKDIYLHALVRD 526
Query: 532 PDGRKMSKSYGNVVAPDEVIPKYGADALRLWTA-LAPPGEDHPFKWETVDYNFRFLQKVW 590
G KMSKS GNV+ P E+I KYGAD+LR A L G D ++ N F K++
Sbjct: 527 EKGEKMSKSKGNVIDPLEMIEKYGADSLRFTLANLCATGRDIKLSTTHLENNKNFANKLF 586
Query: 591 NIYRFAERHIKDF-DYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMT 649
N + + + F D E+ + + L R+ SRL+ + K L+ YRFN T L
Sbjct: 587 NAASYLKLKQESFKDKERLNEYQ-TALGRYAKSRLNLVTKEVRNALDNYRFNDATTLLYR 645
Query: 650 FIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMF 709
F+W E D +IE K DE L +L + LL PF+P I+E +YH +
Sbjct: 646 FLWGEFCDWFIEFSKVENEAIDE---------LGSVLKEALKLLHPFMPFISESLYHKLS 696
Query: 710 KDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAI 769
++ E + ++ P +E DEK E E+ + + +R+ K P L+ ++
Sbjct: 697 NTEL-ENAHSIMVMPYPKEIAQDEKLEHEFEVIKDCIVSLRRLKIMLETP-PIVLKEASV 754
Query: 770 YALESYDDLKLIEKDIAGTMNIEKLEIFKGEP--------------------QLEERIVE 809
E ++ + ++ +EK+ + +P L I
Sbjct: 755 GLREKIENTERLQNYAQKLAKLEKVSVITYKPLKSVSDVGEFCQTYADLENLDLSPLIAR 814
Query: 810 VKPNYKRIGPRYGKLVPRIVEHLKNNAESIAREIKENGKVEFEIDGE 856
+K +++ KL +KN +S+ + +E+ K E +G+
Sbjct: 815 LKKQLEKLEKEKLKLNLHNENFVKNAPKSVLEKARESLKTLLEKEGK 861
>pir||E75554 valyl-tRNA synthetase - Deinococcus radiodurans (strain R1)
>gi|6457813|gb|AAF09735.1|AE001877_2 (AE001877)
valyl-tRNA synthetase [Deinococcus radiodurans]
Length = 913
Score = 374 bits (950), Expect = e-102
Identities = 280/935 (29%), Positives = 442/935 (46%), Gaps = 94/935 (10%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
LP ++DP IEPKW W E ++ K + I PPP +G LHLGH L +T ID
Sbjct: 9 LPTQFDPTGIEPKWAARWRSEP-FRADATSGKDPFTIVIPPPNVTGNLHLGHALDNTLID 67
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVE---KEFGITKDQ--PEEFLKKCVEWTWQA 116
+ RYKRM G+ L+ G D+ G+ T++ VE K+ G ++ E FL+K EW ++
Sbjct: 68 TLIRYKRMAGFEALYLPGMDHAGISTQVVVERQLKDAGTSRHDLGREAFLEKVWEWKGKS 127
Query: 117 IEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRT 176
+ Q R+G SADW E TMD+ AV+ ++ Y GL YR E V W P +T
Sbjct: 128 GGMILDQLTRLGVSADWTRERFTMDEGLSRAVRTQFVKLYHDGLAYRGERIVNWDPASQT 187
Query: 177 SLAKAEVGYVEEEGYLYYIKLPLADGS--------GYIPIATTRPELMPACVAVFVHPDD 228
+L++ E+ +G +Y + L + + G I IAT RPE + A A+ VHP+D
Sbjct: 188 TLSELEIDREVRKGKMYTLSYKLENSAERGSNGETGEIRIATVRPETIFADQAIAVHPED 247
Query: 229 ERYKHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVII 288
ER++HLVG+K ++P+ +R VPI+ADE V+ FG GA+ D D +R+ L
Sbjct: 248 ERFRHLVGQKARIPLTDRWVPIIADEAVEMEFGVGALKITPAHDPTDFEVGERHGLERPS 307
Query: 289 AINEDGTMNENA---GPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCM 345
I+ DG + + + GL+ ARK + + LE+ G L + +K + +ER+
Sbjct: 308 VIDLDGNLTRDELVPAEFQGLERFAARKAVVKALEESGDLLE-QKDHDTAIGLSERTK-- 364
Query: 346 APIELLPKKQWFIRVKDFTDEIVKVAK--EINWYPEDMFLRLKDWAESMDWDWVISRQRV 403
P+E + +QWF+++K F D++++ EI PE +DW E++ DW ISRQ
Sbjct: 365 VPVEPIISEQWFVKMKPFADQVLEGLDKGEIKLVPERYTKVNRDWLENIR-DWNISRQLW 423
Query: 404 FGTPFPFWVCKNGHI-IPAREE---DLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVD 459
+G P W K G+I +P E D DPR+ + + P DV D W
Sbjct: 424 WGHQIPAWYDKEGNIYVPDPENPELDCDQDPRYAHLNLRRDP----------DVFDTWFS 473
Query: 460 SSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKP 519
S++ P W + D F +PT + G DI+ W + LTG+ P
Sbjct: 474 SNLWPFSTLGWPDTDSED------FRKFYPTQVLVTGYDILFFWVARMQMAGYGLTGQAP 527
Query: 520 WKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRL-WTALAPPGEDHPFKWET 578
+ ++++G+ G+KMSKS GN + P E+ +YG DA R +T L+ G+D
Sbjct: 528 FSTVMLHGLYLDAKGQKMSKSKGNGIDPLELFGQYGVDACRFAFTFLSTGGQDIKHDARR 587
Query: 579 VDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDI--------------------------- 611
+ F K+WN RFA + + E D+
Sbjct: 588 FEQGRNFANKLWNATRFALMRLGEARIEGSDDLSAYVRAAVTLPDGVLLRSKDVLAQLKE 647
Query: 612 --ELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYG 669
+L DRWI+SRL+ + A+ +L+ + R L +F W E D YIE K L
Sbjct: 648 RDDLTLADRWIISRLNDVTAEASAQLDAFDIGAAIRTLYSFTWDEFCDWYIEAAKPEL-- 705
Query: 670 DDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYRED 729
L L +L +V+ LL PF+P IT E+Y A+ + + + SWP+
Sbjct: 706 --ASGNLGTMATLKVVLEHVLKLLHPFMPFITSELYAALGH----RRQIAVHSWPQPDAA 759
Query: 730 RIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESYDDLKLIEKDIAGTM 789
D +A K + R V R K+ G+ +L +VA+ D ++ ++
Sbjct: 760 LHDAEATKAFDALRSAVDSARSLKSELGLSPQDRL-NVAV----DGDLADVVRQNARVVE 814
Query: 790 NIEKLEIFKGEPQLEER-IVEVKPNYKRIGPRYGKL-VPRIVEHLKNNAESIAREIKE-N 846
I ++ + P LE R + +V P + P G + + V+ + + ++IK+
Sbjct: 815 GIARVNLV---PALEGRTLSQVAPGVTILAPLEGTVDIADWVKKQQKRLAELDKQIKQAQ 871
Query: 847 GKVEFE--IDGEKVELTKEDVMIKKEVFSEGERVE 879
GK+ E + E+ +E+ + ++ ER+E
Sbjct: 872 GKLNNEGFVARAPAEVIEEEKRRVADFGAQKERLE 906
>sp|P96142|SYV_THETH VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|1814011|emb|CAA71837.1| (Y10900) valyl-tRNA
synthetase [Thermus thermophilus]
Length = 854
Score = 370 bits (940), Expect = e-101
Identities = 278/899 (30%), Positives = 442/899 (48%), Gaps = 69/899 (7%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
LPK YDP +EPKW + W + + KP + I PPP +G+LH+GH L ++ D
Sbjct: 3 LPKAYDPKSVEPKWAEKWAKNP-FVANPKSGKPPFVIFMPPPNVTGSLHMGHALDNSLQD 61
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEK---EFGITKDQ--PEEFLKKCVEWTWQA 116
+ RYKRMRG+ ++ G D+ G+ T++ VE+ + G T+ E+FL++ +W ++
Sbjct: 62 ALIRYKRMRGFEAVWLPGTDHAGIATQVVVERLLLKEGKTRHDLGREKFLERVWQWKEES 121
Query: 117 IEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRT 176
+ KQ R+G SADW E TMD+ AV + +Y +GL YR V WCP+C T
Sbjct: 122 GGTILKQLKRLGASADWSREAFTMDE-NAPAVPYAFSRYYHEGLAYRAPRLVNWCPRCET 180
Query: 177 SLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVG 236
+L+ EV G LY ++ + +G G+I IAT RPE + A A+ VHP+DERY+HL+G
Sbjct: 181 TLSDLEVETEPTPGKLYTLRYEV-EGGGFIEIATVRPETVFADQAIAVHPEDERYRHLLG 239
Query: 237 KKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTM 296
K+ + +PILAD V+ +FGTGA+ D D +R+ L + IN +G M
Sbjct: 240 KRAR-------IPILADPAVEKDFGTGALKVTPAHDPLDYEIGERHGLKPVSVINLEGRM 292
Query: 297 NENAGPYA--GLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKK 354
P A GL EAR+K E + G L K+E + S C PIE
Sbjct: 293 EGERVPEALRGLDRFEARRKAVELFREAGHLVKEEDY---TIALATCSRCGTPIEYAIFP 349
Query: 355 QWFIRVKDFTDEIVKVAK--EINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWV 412
QW++R++ +E++K + +I + PE DW E++ DW ISRQ +G P W
Sbjct: 350 QWWLRMRPLAEEVLKGLRRGDIAFVPERWKKVNMDWLENVK-DWNISRQLWWGHQIPAWY 408
Query: 413 CKNGHIIPAREEDLPVDPRFDKPPVEKCPVCGA-EIEPVTDVLDCWVDSSITPLIITRWH 471
C++ + ++P R+ + P C CG+ ++ DV D W S++ PL W
Sbjct: 409 CEDCQAV-----NVPRPERYLEDPT-SCEACGSPRLKRDEDVFDTWFSSALWPLSTLGWP 462
Query: 472 EAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAG 531
E + E K F +P + G DI+ W + G++P+K ++++G+V
Sbjct: 463 E----ETEDLKAF---YPGDVLVTGYDILFLWVSRMEVSGYHFMGERPFKTVLLHGLVLD 515
Query: 532 PDGRKMSKSYGNVVAPDEVIPKYGADALRL-WTALAPPGEDHPFKWETVDYNFRFLQKVW 590
G+KMSKS GNV+ P E++ +YGADALR LA G+D ++ F K++
Sbjct: 516 EKGQKMSKSKGNVIDPLEMVERYGADALRFALIYLATGGQDIRLDLRWLEMARNFANKLY 575
Query: 591 NIYRFAERHIKDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTF 650
N RF + F + K+ DR++ +RL R ++ T E RE+
Sbjct: 576 NAARFVLLSREGF---QAKEDTPTLADRFMRTRLSRGVEEITALYEALDLAQAAREVYEL 632
Query: 651 IWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFK 710
+W E D Y+E K L + + L E+L ++ LL P +P +T E+Y A+
Sbjct: 633 VWSEFCDWYLEAAKPALKAGNAHTLR----TLEEVLAVLLKLLHPMMPFLTSELYQAL-- 686
Query: 711 DKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIY 770
G++ + L +WPE DE+AE+ E ++ V+ +R K G+P + V +Y
Sbjct: 687 --TGKEELALEAWPE--PGGRDEEAERAFEALKQAVTAVRALKAEAGLP---PAQEVRVY 739
Query: 771 ALESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVE 830
LE + +E+++ + + ++ P + +V+ P P G L VE
Sbjct: 740 -LEG--ETAPVEENLEVFRFLSRADLLPERP--AKALVKAMPRVTARMPLEGLL---DVE 791
Query: 831 HLKNNAESIARE---IKENGKVEFEIDGEKVELTKEDVMIK----KEVFSEGERVETAV 882
+ E +E + E + + G + + KE V + KE + ER+ A+
Sbjct: 792 EWRRRQEKRLKELLALAERSQRKLASPGFREKAPKEVVEAEEARLKENLEQAERIREAL 850
>emb|CAB57581.1| (Y18930) isoleucyl-tRNA synthetase [Sulfolobus solfataricus]
Length = 986
Score = 369 bits (936), Expect = e-100
Identities = 263/894 (29%), Positives = 434/894 (48%), Gaps = 106/894 (11%)
Query: 61 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP-------EEFLKKCVEWT 113
D I RY+R+ G V G+D HGLP E+ EK GI+ Q E F+ KC E+
Sbjct: 4 DCILRYQRVLGKRVHDQPGYDTHGLPIEVATEKLLGISNKQEIIDKIGVETFINKCKEFA 63
Query: 114 WQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPK 173
+ M + F +G DW+ Y+T+D Y ++ + + Y+KG++ + ++WCP+
Sbjct: 64 LSNADKMTQNFKNVGVFMDWERPYYTLDPSYISSSWSVIKKAYEKGMLDKGTAVLHWCPR 123
Query: 174 CRTSLAKAEVG-YVEEEGYLYYIKLPL-ADGSGYIPIATTRPELMPACVAVFVHPDDE-- 229
C T+L+ EV Y + E Y+K + + + Y+ I TT P +P+ V V ++ D +
Sbjct: 124 CETTLSDYEVSEYRDLEDPSIYVKFKIKGEKNRYLLIWTTTPWTIPSNVFVMINKDYDYA 183
Query: 230 ------------------------------------------RYKH----LVGKKVKLPI 243
+Y+H V + KL
Sbjct: 184 DVEVNGEILVIAKDRVEAVMKEASITNYKILRTYKGSELIGIKYEHPLREFVSAQTKLDD 243
Query: 244 YEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPY 303
+ + V A V GTG V++ T E+D ++Y PV++ +N+ G E G Y
Sbjct: 244 FHQVVD--AGNIVTLTDGTGLVHSATGHGEEDFTVGQKYGFPVVMFVNDRGEFTEEGGKY 301
Query: 304 AGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDF 363
GLKV +A K I DL+ L+ + KI HR + C P+ L QWFIRV
Sbjct: 302 KGLKVRDASKAIISDLKSKNTLFFEGKIVHR---YPVCWRCKTPLILRAIDQWFIRVTKI 358
Query: 364 TDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCK---NGHIIP 420
D+++ +++NW P+ R+ + + + DWVISRQR +GTP P W+C+ N ++
Sbjct: 359 KDKMLNEIEKVNWIPDWGKSRISNMVKELR-DWVISRQRFWGTPLPIWICERCNNVMVVG 417
Query: 421 AREE--DLPVDP---RFDKPPVE----KCPVCGAEIEPVTDVLDCWVDSSITPLIITRWH 471
++EE + +DP +P ++ KC CG + + DV D W DS +
Sbjct: 418 SKEELESIAIDPVPNDLHRPWIDNVRVKCNKCGGVAKRIPDVADVWFDSGVAFF------ 471
Query: 472 EAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAG 531
A G + +KW E P L +G D +R W F + L + P+ ++++G +
Sbjct: 472 -ASLGKDWQEKWKELG-PVDLVLEGHDQLRGWFFSLLRSGLILLDRAPYTSVLVHGFMLD 529
Query: 532 PDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWN 591
GR+M KS GN V P V+ KYG D LRLW ED F W+ ++ R LQ +WN
Sbjct: 530 EQGREMHKSLGNYVEPSVVVEKYGRDILRLWLLRNTTWEDAKFSWKALELTKRDLQIIWN 589
Query: 592 IYRFAERH--IKDFDYEKY------KDIELEPLDRWILSRLHRIIKFATEELERYRFNLI 643
+ FA + + +F+ +KY K ++E D WILSR + ++K E ++ Y+ + +
Sbjct: 590 TFVFASMYMNLDNFEPDKYTLDDIIKYAKIE--DLWILSRFNSMLKKVNESMKDYKVHEM 647
Query: 644 TRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVM----LLLAPFVPH 699
T L+ F+ +V+ YI +++ R + E+ + K+A+Y +LY ++ +L + +P
Sbjct: 648 TNYLINFLIEDVSRFYIRLIRKRAW---IEANTQDKIAMYYILYYILKQWIILASTIIPF 704
Query: 700 ITEEIYHAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMP 759
I+E+IY + + ++SV + S Y E ID + E+ E+AR++ + G+
Sbjct: 705 ISEKIYKSFVVN--AKESVSMESSINYDERFIDNELERAFEVAREINEASLNARAKAGIK 762
Query: 760 LNAKLEHVAIYALESYDDLKLIE--KDIAGTM-NIEKLEIFKGEPQLEERIVEVKPNYKR 816
L L V I+ +E+ D L + KD+ +M N + +EI K E +V+PN
Sbjct: 763 LRWPLAKVYIF-IENEDTLAKVGRIKDVLISMLNAKDIEISKIEGFKSFSKYKVEPNRSI 821
Query: 817 IGPRYGKLVPRIVEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVMIKKE 870
IG Y + P+IVE+++NN + IA +I + +ID + L V+I +E
Sbjct: 822 IGKEYKSMSPKIVEYIENNRDIIAMDILNKKQHVAKIDNFDIILNASYVIISEE 875
>pir||H81686 valyl-tRNA synthetase TC0576 [imported] - Chlamydia muridarum
(strain Nigg) >gi|7190615|gb|AAF39411.1| (AE002326)
valyl-tRNA synthetase [Chlamydia muridarum]
Length = 939
Score = 369 bits (936), Expect = e-100
Identities = 247/764 (32%), Positives = 370/764 (48%), Gaps = 92/764 (12%)
Query: 3 PKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDI 62
PK YDP E +W ++ + KP+Y+I PPP +G LH+GH L +T D+
Sbjct: 7 PKAYDPKSSESGVYSFWERSGMFIADANSKKPAYSIVMPPPNVTGILHMGHALVNTLQDM 66
Query: 63 IARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGI------TKDQPEEFLKKCVEWTWQA 116
+ RYKRM+G+ V + G D+ G+ T+ VE+ T EEFLK EW ++
Sbjct: 67 LIRYKRMKGFEVCWVPGTDHAGIATQTVVERHLRSSLGKRRTDFSREEFLKHVWEWKEKS 126
Query: 117 IEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRT 176
+ Q ++G S DW + TMD AV+K+ + KG+IYR + V W P +T
Sbjct: 127 QNVILSQLRQLGCSCDWSRQRFTMDPEANRAVKKAFKVLFDKGVIYRGYYLVNWDPILQT 186
Query: 177 SLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVG 236
+LA EV Y E EG+LYYI+ P+ + +I +ATTRPE + A+ V P+DERY HL+G
Sbjct: 187 ALADDEVEYEEREGWLYYIRYPVVNSEEFITVATTRPETLLGDTAIAVSPEDERYSHLIG 246
Query: 237 KKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTM 296
KV +P +RE+PI+ D VD +FGTGAV D+ D + LP+I + G +
Sbjct: 247 AKVIVPFVDREIPIIGDFSVDASFGTGAVKITPAHDKDDYRTGMNHRLPMINILTPTGEI 306
Query: 297 NENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQW 356
NEN G + GL E AR+ I LE +GL +KE RV + RS A IE KQW
Sbjct: 307 NENGGIFTGLAKESARENIITSLEALGLFVRKEAYSSRV-GVSYRSG--AIIEPYLSKQW 363
Query: 357 FIRVKDFTDEIVKV--AKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFW--- 411
F+ V F + + + +KEIN +P + W ++ DW ISRQ +G P W
Sbjct: 364 FVSVDSFRESLREFVNSKEINLFPPEFIRNYLTWVNNLK-DWCISRQLWWGHRIPVWHNK 422
Query: 412 ------VCKNGHIIPAREEDLPVDPR--FDKPPVEKCPVCGAEIEPVTDVLDCWVDSSIT 463
+C +G +P E++ DP + P DVLD W S +
Sbjct: 423 HDEEYVICFDGDGVP---EEVAQDPESWYQDP----------------DVLDTWFSSGLW 463
Query: 464 PLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDI 523
PL W E + +K+ +PT++ G DI+ W + + KP+ D+
Sbjct: 464 PLTCFGWPEE---SADLRKF----YPTSVLVTGHDILFFWVTRMVLMCSAMVDTKPFADV 516
Query: 524 VINGMVAGPDGR----------------------------------KMSKSYGNVVAPDE 549
++G++ G + K+SKS GNV+ P E
Sbjct: 517 FLHGLIFGKSYKQYDDNGEWTYVSGDQKREYDKGKALPKNVVAKWEKLSKSKGNVIDPIE 576
Query: 550 VIPKYGADALRL-WTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDF---DY 605
+I YGADA+R + A GE + + F+ K+WN RF HI + D
Sbjct: 577 MIDMYGADAVRFTLCSCANRGEQIDLDYRLFEEYKNFVNKLWNGARFIFGHISELTSRDL 636
Query: 606 EKYKDIELEPL-DRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVK 664
E+ + +L L D +IL R + ++ Y F+ I F +++ Y+E++K
Sbjct: 637 EEGVNKDLLGLEDFYILDRFNELLALIDSHYNCYSFDKIAALAYDFFKNDLCSTYLEIIK 696
Query: 665 YRLY---GDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIY 705
L+ G+DE+ K K+ L LL N++ +L P VP+ITE ++
Sbjct: 697 PTLFGKQGNDEQRATKRKL-LATLLVNILGVLHPIVPYITETLF 739
>gb|AAK41020.1| Isoleucine-tRNA synthetase (ileS) [Sulfolobus solfataricus]
Length = 986
Score = 369 bits (936), Expect = e-100
Identities = 263/894 (29%), Positives = 434/894 (48%), Gaps = 106/894 (11%)
Query: 61 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP-------EEFLKKCVEWT 113
D I RY+R+ G V G+D HGLP E+ EK GI+ Q E F+ KC E+
Sbjct: 4 DCILRYQRVLGKRVHDQPGYDTHGLPIEVATEKLLGISNKQEIIDKIGVETFINKCKEFA 63
Query: 114 WQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPK 173
+ M + F +G DW+ Y+T+D Y ++ + + Y+KG++ + ++WCP+
Sbjct: 64 LSNADKMTQNFKNVGVFMDWERPYYTLDPSYISSSWSVIKKAYEKGMLDKGTAVLHWCPR 123
Query: 174 CRTSLAKAEVG-YVEEEGYLYYIKLPL-ADGSGYIPIATTRPELMPACVAVFVHPDDE-- 229
C T+L+ EV Y + E Y+K + + + Y+ I TT P +P+ V V ++ D +
Sbjct: 124 CETTLSDYEVSEYRDLEDPSIYVKFKIKGEKNRYLLIWTTTPWTIPSNVFVMINKDYDYA 183
Query: 230 ------------------------------------------RYKH----LVGKKVKLPI 243
+Y+H V + KL
Sbjct: 184 DVEVNGEILVIAKDRVEAVMKEASITNYKILRTYKGSELIGIKYEHPLREFVSAQTKLDD 243
Query: 244 YEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPY 303
+ + V A V GTG V++ T E+D ++Y PV++ +N+ G E G Y
Sbjct: 244 FHQVVD--AGNIVTLTDGTGLVHSATGHGEEDFTVGQKYGFPVVMFVNDRGEFTEEGGKY 301
Query: 304 AGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDF 363
GLKV +A K I DL+ L+ + KI HR + C P+ L QWFIRV
Sbjct: 302 KGLKVRDASKAIISDLKSKNTLFFEGKIVHR---YPVCWRCKTPLILRAIDQWFIRVTKI 358
Query: 364 TDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCK---NGHIIP 420
D+++ +++NW P+ R+ + + + DWVISRQR +GTP P W+C+ N ++
Sbjct: 359 KDKMLNEIEKVNWIPDWGKSRISNMVKELR-DWVISRQRFWGTPLPIWICERCNNVMVVG 417
Query: 421 AREE--DLPVDP---RFDKPPVE----KCPVCGAEIEPVTDVLDCWVDSSITPLIITRWH 471
++EE + +DP +P ++ KC CG + + DV D W DS +
Sbjct: 418 SKEELESIAIDPVPNDLHRPWIDNVRVKCNKCGGVAKRIPDVADVWFDSGVAFF------ 471
Query: 472 EAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAG 531
A G + +KW E P L +G D +R W F + L + P+ ++++G +
Sbjct: 472 -ASLGKDWQEKWKELG-PVDLVLEGHDQLRGWFFSLLRSGLILLDRAPYTSVLVHGFMLD 529
Query: 532 PDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWN 591
GR+M KS GN V P V+ KYG D LRLW ED F W+ ++ R LQ +WN
Sbjct: 530 EQGREMHKSLGNYVEPSVVVEKYGRDILRLWLLRNTTWEDAKFSWKALELTKRDLQIIWN 589
Query: 592 IYRFAERH--IKDFDYEKY------KDIELEPLDRWILSRLHRIIKFATEELERYRFNLI 643
+ FA + + +F+ +KY K ++E D WILSR + ++K E ++ Y+ + +
Sbjct: 590 TFVFASMYMNLDNFEPDKYTLDDIIKYAKIE--DLWILSRFNSMLKKVNESMKDYKVHEM 647
Query: 644 TRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVM----LLLAPFVPH 699
T L+ F+ +V+ YI +++ R + E+ + K+A+Y +LY ++ +L + +P
Sbjct: 648 TNYLINFLIEDVSRFYIRLIRKRAW---IEANTQDKIAMYYILYYILKQWIILASTIIPF 704
Query: 700 ITEEIYHAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMP 759
I+E+IY + + ++SV + S Y E ID + E+ E+AR++ + G+
Sbjct: 705 ISEKIYKSFVVN--AKESVSMESSINYDERFIDNELERAFEVAREINEASLNARAKAGIK 762
Query: 760 LNAKLEHVAIYALESYDDLKLIE--KDIAGTM-NIEKLEIFKGEPQLEERIVEVKPNYKR 816
L L V I+ +E+ D L + KD+ +M N + +EI K E +V+PN
Sbjct: 763 LRWPLAKVYIF-IENEDTLAKVGRIKDVLISMLNAKDIEISKIEGFKSFSKYKVEPNRSI 821
Query: 817 IGPRYGKLVPRIVEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVMIKKE 870
IG Y + P+IVE+++NN + IA +I + +ID + L V+I +E
Sbjct: 822 IGKEYKSMSPKIVEYIENNRDIIAMDILNKKQHVAKIDNFDIILNASYVIISEE 875
>sp|O83998|SYV_TREPA VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437656|pir||B71250 valine--tRNA ligase (EC 6.1.1.9)
(valS) - syphilis spirochete >gi|3323365|gb|AAC26589.1|
(AE001271) valyl-tRNA synthetase (valS) [Treponema
pallidum]
Length = 956
Score = 366 bits (929), Expect = e-100
Identities = 256/812 (31%), Positives = 390/812 (47%), Gaps = 76/812 (9%)
Query: 1 MLPKKYDPNEIEPKWQKYWLEEKIYKYR------------------LDENKPSYAIDTPP 42
+LP Y P + E + W + + + R ++ ++ I PP
Sbjct: 9 VLPPVYGPADFEARVYACWEQRQAFSPRARGSGTSDSEGCDGHSRQIEGGARTFVIAIPP 68
Query: 43 PFTSGTLHLGHVLSHTWIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEF---GITK 99
P +G LH+GH L+ DI+ RY+RM G L+ G D+ G+ T+ VE+ GI K
Sbjct: 69 PNITGVLHMGHCLNTVLQDIVIRYQRMAGACTLWIPGTDHAGIATQHVVERALRKEGIHK 128
Query: 100 DQP--EEFLKKCVEWTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYK 157
+ E+F+ + + + +R Q ++G S DW E T+D A+V+++ + Y+
Sbjct: 129 REVTREQFVARTQQIKDSHQDTIRMQLRKMGASCDWTCERFTLDAGMSASVREAFVTLYE 188
Query: 158 KGLIYREEHPVYWCPKCRTSLAKAEVGYVEEEGYLYYIKLPLA-----DGSGYIP----- 207
+GL+YR + V WCP+C T+L+ EV + E++G LYY++ PL +G+G P
Sbjct: 189 RGLLYRSMYLVNWCPRCGTALSDDEVFHQEKDGALYYVRYPLLPRTEEEGNGVPPPLGTA 248
Query: 208 -------IATTRPELMPACVAVFVHPDDERYKHLVGKKVKLPIYEREVPILADEDVDPNF 260
IATTRPE + A VAV VHPDD RY+ L+G+KV +P+ R VPI+AD V +F
Sbjct: 249 QVGETIIIATTRPETILADVAVAVHPDDARYQSLIGRKVCVPMVNRIVPIIADSYVAQDF 308
Query: 261 GTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENA-GPYAGLKVEEARKKIAEDL 319
GTG V D D R++L I +N DG++N+ Y GL +AR +I DL
Sbjct: 309 GTGMVKITPAHDPNDWDIGTRHSLEAINMLNPDGSLNDQVPAAYRGLSCAQARIQIVADL 368
Query: 320 EKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAK--EINWY 377
+ GLL ++E+I H V C A IE QWF+++K + + K ++ ++
Sbjct: 369 QAHGLLSREERIVHSV---GVCYRCEAVIEPYLSLQWFVKMKPLASQALAAWKRADVQFH 425
Query: 378 PEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVDPRFDKPPV 437
P+ W E + DW ISRQ +G P W C A++ VD V
Sbjct: 426 PKKWENTYVRWLEHIR-DWCISRQLWWGHRIPVWYCAQC----AQQTVSRVD-------V 473
Query: 438 EKCPVCG-AEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQG 496
++C CG A+I DVLD W S + P W +E +K +PT+
Sbjct: 474 QRCAHCGSADITQDPDVLDTWFSSWLWPFSTLGW------PQETQK-LRAFYPTSAVITA 526
Query: 497 TDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGA 556
DII W I + T P++D+ ++G+V GRKMSKS N V P +I YGA
Sbjct: 527 YDIIFFWVARMIMAGLEFTQTVPFRDVYLHGLVRDKQGRKMSKSLNNGVDPLHIIRTYGA 586
Query: 557 DALRLWTA-LAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIELEP 615
DALR A + G+D + ++ RF KVWN R+ +++ + L
Sbjct: 587 DALRFTLAFMCAQGQDVLIEMDSFKMGSRFANKVWNASRYILGNLEGRRVYAIAHVSLTE 646
Query: 616 LDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESK 675
LDRWI + ++ LE YRFN + + F W+ D Y+E K DE+ K
Sbjct: 647 LDRWIFHTFNETVQQVRTALEAYRFNDAAQAVYEFFWNSFCDWYVEASKCSFQKPDEQEK 706
Query: 676 LKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKD-----KIGEKSVHLL----SWPEY 726
+A L LL + LL PF+P +TEEIY ++ + H L +P Y
Sbjct: 707 DRAASVLCTLLEETLRLLHPFLPFVTEEIYRSLSPSVHDTTQAIPSGAHALLMCAPYPVY 766
Query: 727 REDRIDEKAEKLGELARKVVSEMRKYKNSHGM 758
R+D +A +++V +R + + G+
Sbjct: 767 VPSRVDARACAHIGAVQEIVRAVRTLRAACGI 798
>sp|P43834|SYV_HAEIN VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|1075441|pir||G64121 valine--tRNA ligase (EC 6.1.1.9)
- Haemophilus influenzae (strain Rd KW20)
>gi|1574225|gb|AAC23038.1| (U32819) valyl-tRNA
synthetase (valS) [Haemophilus influenzae Rd]
Length = 954
Score = 365 bits (927), Expect = 1e-99
Identities = 274/945 (28%), Positives = 431/945 (44%), Gaps = 114/945 (12%)
Query: 5 KYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIA 64
+++P+ +E + W E +K +EN PSY I PPP +G+LH+GH T +D +
Sbjct: 10 RFNPSAVEQALYQRWEESGYFKPSENENAPSYCIAIPPPNVTGSLHMGHAFQQTLMDTLI 69
Query: 65 RYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCVEWTWQAIE 118
R+ RM G+N L+ G D+ G+ T++ VE++ + + E F+ K +W +
Sbjct: 70 RFNRMEGHNTLWQTGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFINKIWDWKAYSGG 129
Query: 119 AMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSL 178
+ +Q R+G S DW+ E TMDD AV++ + +++GLIYR + V W PK T++
Sbjct: 130 TISQQMRRLGNSIDWERERFTMDDGLSNAVKEVFVRLHEEGLIYRGKRLVNWDPKLHTAI 189
Query: 179 AKAEVGYVEEEGYLYYIKLPLA------DGSGYIPIATTRPELMPACVAVFVHPDDERYK 232
+ EV E +G L++ + PLA DG Y+ +ATTRPE M AV VHP+DERY+
Sbjct: 190 SDLEVENKESKGSLWHFRYPLANDAKTADGKDYLVVATTRPETMLGDTAVAVHPEDERYQ 249
Query: 233 HLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINE 292
L+GK V LP+ RE+PI+ADE VD FGTG V D D KR+NLP++ +
Sbjct: 250 SLIGKTVVLPLANREIPIIADEYVDREFGTGVVKITPAHDFNDYEVGKRHNLPMVNVLTL 309
Query: 293 DGTMNENA------------------GPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHR 334
+ + + A Y GL+ ARKKI D E +GLL ++IK
Sbjct: 310 NANIRDEAEIIGTDGKPLAGYEATIPADYRGLERFAARKKIVADFEALGLL---DEIKPH 366
Query: 335 VLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAK--EINWYPEDMFLRLKDWAESM 392
L+ PIE + QW++ VK D +K + EI + P+ W +
Sbjct: 367 DLKVPYGDRGGVPIEPMLTDQWYVSVKPLADVAIKAVEDGEIQFVPKQYENLYFSWMRDI 426
Query: 393 DWDWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTD 452
DW ISRQ +G P W G++ AR E+ V +++ E++ D
Sbjct: 427 Q-DWCISRQLWWGHRIPAWYDAEGNVYVARNEE-EVRSKYNLDSA-------VELKQDED 477
Query: 453 VLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTF 512
VLD W S + W E K E K + PT + G DII W I T
Sbjct: 478 VLDTWFSSGLWTFSTLGWPEQTK---ELKMFH----PTDVLITGFDIIFFWVARMIMFTM 530
Query: 513 KLT----GKK--PWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIP-------------- 552
GK P+K + + G++ G+KMSKS GNV+ P ++I
Sbjct: 531 HFVKDENGKPQVPFKTVYVTGLIRDEQGQKMSKSKGNVLDPIDMIDGISLEDLLEKRTGN 590
Query: 553 -----------------------KYGADALRLW-TALAPPGEDHPFKWETVDYNFRFLQK 588
+G DALR ALA G D + + ++ F K
Sbjct: 591 MMQPQLAEKIAKATRKEFAEGIAAHGTDALRFTLAALASNGRDINWDMKRLEGYRNFCNK 650
Query: 589 VWNIYRFAERHIKDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELM 648
+WN RF + K D + +IE DRWI S +R ++ L +YRF+L +
Sbjct: 651 LWNASRFVLTNEK-LDLSQ-GEIEFSLADRWIQSEFNRTVETFRSSLSQYRFDLCANAIY 708
Query: 649 TFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAM 708
F W++ D Y+E+ K + A L +L ++ L P +P ITEEI+ +
Sbjct: 709 EFTWNQFCDWYLELTKPVFANGNAAQIRAASQTLVHVLEKLLRLAHPLIPFITEEIWQKV 768
Query: 709 FKDKIG--EKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEH 766
K +G S+ L +P+ E D +AE E ++V+ +R + + + L+
Sbjct: 769 -KGFVGITADSIMLQPFPQVEESGFDPEAEAEIEWLKEVIVAVRNIRAESNIAPSKGLD- 826
Query: 767 VAIYALESYDDLKLIEKDIA---GTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGK 823
++ S ++ K++EK A ++ +++ + ++ N + + P G
Sbjct: 827 -LLFRNLSAENAKILEKQTALLKAMAKLDNVQVLATNETAPLAVAKLVGNAELLVPMAGF 885
Query: 824 LVPRIVEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVMIK 868
+ N +AR KE K + E+ + +L+ E + K
Sbjct: 886 I---------NKEAELARLTKEIEKYQNEVKRIENKLSNEAFVAK 921
>sp|Q9Z987|SYV_CHLPN VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437658|pir||B72120 valine--tRNA ligase (EC 6.1.1.9)
[similarity] - Chlamydophila pneumoniae (strains CWL029
and AR39) >gi|4376354|gb|AAD18247.1| (AE001595) Valyl
tRNA Synthetase [Chlamydophila pneumoniae CWL029]
>gi|7189594|gb|AAF38490.1| (AE002226) valyl-tRNA
synthetase [Chlamydophila pneumoniae AR39]
>gi|8978467|dbj|BAA98304.1| (AP002545) alyl tRNA
synthetase [Chlamydophila pneumoniae J138]
Length = 940
Score = 363 bits (922), Expect = 5e-99
Identities = 239/754 (31%), Positives = 371/754 (48%), Gaps = 71/754 (9%)
Query: 3 PKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDI 62
PK Y+ + EP+ +W + ++K +KP Y++ PPP +G LH+GH L +T D+
Sbjct: 7 PKAYNFQDTEPELYVFWEKNGMFKAEASSDKPPYSVIMPPPNVTGVLHMGHALVNTLQDV 66
Query: 63 IARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCVEWTWQA 116
+ RYKRM G+ V + G D+ G+ T+ VE+ ++ + E+FLK W ++
Sbjct: 67 LVRYKRMSGFEVCWIPGTDHAGIATQAVVERHLQASEGKRRTDYSREDFLKHIWAWKEKS 126
Query: 117 IEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRT 176
+ + Q ++G S DWD + TM+ AV+K+ ++ G IYR + V W P +T
Sbjct: 127 EKVVLSQLRQLGCSCDWDRKRFTMEPLANRAVKKAFKTLFENGYIYRGYYLVNWDPVLQT 186
Query: 177 SLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVG 236
+LA EV Y E++G+LYYI+ + I +ATTRPE + V P+DERY +G
Sbjct: 187 ALADDEVEYEEKDGWLYYIRYRMVGSQESIVVATTRPETSLGDTGIAVSPNDERYASWIG 246
Query: 237 KKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTM 296
V++P R++PI+ D VDP FGTGAV D+ D + ++LP+I + G +
Sbjct: 247 ASVEVPFVNRQIPIIGDASVDPTFGTGAVKVTPAHDKDDYLMGTNHHLPMINILTPSGGI 306
Query: 297 NENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQW 356
NEN GP+AG+ E+AR++I LE+ GL +KE K RV + RS A IE KQW
Sbjct: 307 NENGGPFAGMAKEKAREEILIALEEQGLFVRKEPYKLRV-GVSYRSG--AVIEPYLSKQW 363
Query: 357 FIRVKDFTDEIVKV--AKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCK 414
F+ V +F + + +++I +P+D W + DW ISRQ +G P W K
Sbjct: 364 FVSVSEFRGALREFVESQDIKIFPKDFVKNYLSWVNHLR-DWCISRQLWWGHRIPVWYHK 422
Query: 415 NG--HIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHE 472
N ++ E +P + D + P DVLD W S + PL W +
Sbjct: 423 NDDERVLCYDGEGIPEEVAQDPDSWYQDP----------DVLDTWFSSGLWPLTCLGWPD 472
Query: 473 AIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAG- 531
+ + KK+ +PTAL G DI+ W + ++G+KP+ ++ ++G++ G
Sbjct: 473 --ENSPDLKKF----YPTALLVTGHDILFFWVTRMVLLCSSMSGEKPFSEVFLHGLIFGK 526
Query: 532 ----------------------------PDG-----RKMSKSYGNVVAPDEVIPKYGADA 558
PDG K+SKS GNV+ P E+I YG DA
Sbjct: 527 SYKRYNDFGEWSYISGKEKLAYDMGEALPDGVVAKWEKLSKSKGNVIDPLEMIATYGTDA 586
Query: 559 LRL-WTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDFD-YEKYKDIELEPL 616
+RL + A GE + + F KVWN RF HI D + I+ + L
Sbjct: 587 VRLTLCSCANRGEQIDLDYRLFEEYKHFANKVWNGARFIFGHISDLQGKDLLAGIDEDSL 646
Query: 617 ---DRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYG--DD 671
D +IL +++I E Y F+ + F +++ YIE++K L+G +
Sbjct: 647 GLEDFYILDGFNQLIHQLEEAYATYAFDKVATLAYEFFRNDLCSTYIEIIKPTLFGKQGN 706
Query: 672 EESKLKAKVALYELLYNVMLLLAPFVPHITEEIY 705
E S+ + L LL NV+ +L P P ITE ++
Sbjct: 707 EASQSTKRTLLAVLLINVLGVLHPVAPFITESLF 740
>pir||G83167 valyl-tRNA synthetase PA3834 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9950009|gb|AAG07221.1|AE004800_10
(AE004800) valyl-tRNA synthetase [Pseudomonas
aeruginosa]
Length = 950
Score = 360 bits (914), Expect = 4e-98
Identities = 268/874 (30%), Positives = 422/874 (47%), Gaps = 104/874 (11%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+ K Y P+ IE W + W E Y E +P Y I PPP +G+LH+GH ++ +D
Sbjct: 1 MDKTYQPHAIETSWYETW-ESNDYFAPSGEGQP-YTIMIPPPNVTGSLHMGHGFNNAIMD 58
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFG---ITKDQ--PEEFLKKCVEWTWQA 116
+ RY+RM+G N L+ G D+ G+ T++ VE++ G +++ E+FL+K EW Q+
Sbjct: 59 ALIRYRRMQGRNTLWQPGTDHAGIATQMVVERQLGAQGVSRHDLGREKFLEKVWEWKEQS 118
Query: 117 IEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRT 176
+ +Q R+G S DW E TMDD AV+++ + ++ GLIYR + V W K T
Sbjct: 119 GGNITRQIRRLGSSVDWSRERFTMDDGLSEAVKEAFVRLHEDGLIYRGKRLVNWDTKLHT 178
Query: 177 SLAKAEVGYVEEEGYLYYIKLPLADGS------GYIPIATTRPELMPACVAVFVHPDDER 230
+++ EV +E+G+L++++ PL +G+ Y+ +ATTRPE + AV VHP+DER
Sbjct: 179 AISDLEVENHDEKGHLWHLRYPLVNGAKTSEGLDYLVVATTRPETLLGDAAVAVHPEDER 238
Query: 231 YKHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAI 290
Y L+G+ +LPI R +PI+ADE VD FGTG V D D KR++LP+I
Sbjct: 239 YAKLIGQFAELPIVGRHIPIIADEYVDREFGTGCVKITPAHDFNDYEVGKRHDLPLINIF 298
Query: 291 NE-------------DGTMNENAGP-----YAGLKVEEARKKIAEDLEKMGLLYKKEKIK 332
++ DG++N N P YAG+ ARK I + E MGLL EK+
Sbjct: 299 DKNAAVLAQAQVFHLDGSVNPNLDPSLPQSYAGMDRFAARKAIVAEFEAMGLL---EKVD 355
Query: 333 HRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKE--INWYPEDMFLRLKDWAE 390
L+ + IE QW++ K ++ + ++ I + P+ W
Sbjct: 356 DHALKVPKGDRSGTVIEPWLTDQWYVSTKPLAEDAIAAVEDGRIQFVPKQYENMYFSWMR 415
Query: 391 SMDWDWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPV 450
+ DW ISRQ +G P W + G++ R+E V+ R + AE+
Sbjct: 416 DIQ-DWCISRQLWWGHRIPAWYDEAGNVYVGRDE---VEVRTKHKLGNE-----AELRQD 466
Query: 451 TDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFR 510
DVLD W S + W + G + ++ + PT + G DII W I
Sbjct: 467 EDVLDTWFSSGL-------WTFSTLGWPQQTEFLKTFHPTDVLVTGFDIIFFWVARMIML 519
Query: 511 TFKL------TGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVI------------- 551
T L T + P+K + ++G+V G+KMSKS GNV+ P +++
Sbjct: 520 TMHLVKNPDGTPQIPFKTVYVHGLVRDGQGQKMSKSKGNVLDPLDIVDGIDLDTLLQKRT 579
Query: 552 -----PK-------------------YGADALRL-WTALAPPGEDHPFKWETVDYNFRFL 586
PK YG DALR + +LA G D F V+ F
Sbjct: 580 SGMMQPKLAEKIAKQTRAEFPEGIASYGTDALRFTFCSLASTGRDIKFDMGRVEGFRNFC 639
Query: 587 QKVWNIYRFAERHIKDFDY-EKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITR 645
K+WN F + D + +EL +DRWI+S+L R + T +L+ +RF+L +
Sbjct: 640 NKIWNAANFVIENTDGQDTGVNGEPVELSSVDRWIISQLQRTEQEVTRQLDAFRFDLAAQ 699
Query: 646 ELMTFIWHEVADDYIEMVKYRLYGDDE--ESKLKAKVALYELLYNVMLLLAPFVPHITEE 703
L FIW E Y+E+VK L+ ++ E + + L +L + L PF+P ITEE
Sbjct: 700 ALYEFIWDEYCAWYLELVKPVLWDENAPIERQRGTRRTLIRVLETALRLAHPFMPFITEE 759
Query: 704 IYHAMFKDKIGEK--SVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLN 761
I+ + K + G++ ++ L WP E RID AE E + ++ +R+ + + +
Sbjct: 760 IWQRI-KGQAGKEGPTLMLQPWPVADEGRIDAAAEGDIEWVKALMLGVRQIRGEMNISMA 818
Query: 762 AKLEHVAIYALESYDDLKLIEKDIAGTMNIEKLE 795
+++ + A S D +L + + M + KLE
Sbjct: 819 KRIDIILKNASPS-DHRRLADNEPL-LMKLAKLE 850
>pir||F81230 valyl-tRNA synthetase NMB0174 [imported] - Neisseria meningitidis
(group B strain MD58) >gi|7225392|gb|AAF40631.1|
(AE002374) valyl-tRNA synthetase [Neisseria meningitidis
MC58]
Length = 945
Score = 359 bits (912), Expect = 7e-98
Identities = 266/890 (29%), Positives = 410/890 (45%), Gaps = 111/890 (12%)
Query: 5 KYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIA 64
KY+P EIE K + W E+ ++ +D KPS++I PPP +GTLH+GH + T +D +
Sbjct: 4 KYNPAEIESKHYQNWEEQGYFQPDMDLTKPSFSIQLPPPNVTGTLHMGHAFNQTIMDGLT 63
Query: 65 RYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQ-----PEEFLKKCVEWTWQAIEA 119
RY RM+G N + G D+ G+ T++ VE++ E+FL+K EW +
Sbjct: 64 RYYRMKGCNTAWIPGTDHAGIATQIVVERQLAAQNVSRHDLGREKFLEKVWEWKEVSGGT 123
Query: 120 MRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLA 179
+ +Q R+G SADW EY TMDD V + + Y++GLIYR + V W P T+++
Sbjct: 124 ITQQMRRVGCSADWTREYFTMDDVRAETVTEVFVRLYEQGLIYRGKRLVNWDPVLGTAVS 183
Query: 180 KAEVGYVEEEGYLYYIKLPLADG-SGYIPIATTRPELMPACVAVFVHPDDERYKHLVGKK 238
EV VEE+G +++I+ PLAD + + +ATTRPE + VAV V+P+DERY HL+GK+
Sbjct: 184 DLEVESVEEQGSMWHIRYPLADNPAEAVIVATTRPETLLGDVAVAVNPEDERYTHLIGKE 243
Query: 239 VKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNE 298
+ LP+ R +P++ADE V+ +FGTG V D D KR++ +I N + +
Sbjct: 244 LILPLTGRTIPVIADEYVEKDFGTGCVKITPAHDFNDYEVGKRHDTRLINVFNLEAKVLA 303
Query: 299 NA----------------GPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERS 342
NA YAGL ARK++ DL++ G L +IK L +
Sbjct: 304 NAEVFNFKGEAQLGFALPEKYAGLDRFAARKQMVADLQEQGFLV---EIKPHTLMTPKGD 360
Query: 343 SCMAPIELLPKKQWFIRVK---------------DFTDEIVKVAKE--INWYPEDMFLRL 385
+ IE + QWF+ + D+ K + + PE+
Sbjct: 361 RTGSVIEPMLTSQWFVAMSATPNGGEPDSEFKGLSLADKAKKAVDSGAVRFIPENWVNTY 420
Query: 386 KDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVDPRFDKPPVEKCPVCGA 445
W ++ DW ISRQ +G P W G++ AR ++ + + K + +
Sbjct: 421 NQWMNNIQ-DWCISRQLWWGHQIPAWYDNEGNVYVARNQE-EAEKQAGKTGLTR------ 472
Query: 446 EIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAF 505
DVLD W S++ P W +E K + P+ + G +II W
Sbjct: 473 ----EEDVLDTWFSSALVPFSTLGWPSE---TDELKAF----LPSNVLVTGYEIIFFWVA 521
Query: 506 YTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAP------------------ 547
I T TGK P+KD+ I+G+V +G+KMSKS GNV+ P
Sbjct: 522 RMIMMTTHFTGKVPFKDVYIHGIVRDHEGKKMSKSEGNVIDPVDLIDGIGLEKLLVKRTT 581
Query: 548 -------------------DEVIPKYGADALRLWTA-LAPPGEDHPFKWETVDYNFRFLQ 587
E IP GADALR A A G F ++ + F
Sbjct: 582 GLRKPETAPKVEEATKKLFPEGIPSMGADALRFTMASYASLGRSVNFDFKRAEGYRNFCN 641
Query: 588 KVWNIYRFAERHIKDFDYEKYKDIELEPL-----DRWILSRLHRIIKFATEELERYRFNL 642
K+WN F + ++ D Y EP D WI+ RL++ I+ T+ E YRF+L
Sbjct: 642 KIWNATNFVLMNTENQDC-GYGATAAEPRGYSFPDMWIVGRLNQTIEQVTQAYETYRFDL 700
Query: 643 ITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITE 702
L +F+W++ D Y+E+ K +L + + L +L + LL P +P ITE
Sbjct: 701 AAETLYSFVWNDYCDWYLELAKVQLQTGCASRQRATRHTLLRVLEAALRLLHPIIPFITE 760
Query: 703 EIYH--AMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPL 760
E++ A D S+ L +PE I + A + + + ++ +R + G+
Sbjct: 761 ELWQTVAPMCDAKTADSIMLARFPEADSGEIVQTAFEQMTVLQDLIGAVRNLRGEMGIQP 820
Query: 761 NAKLEHVAIYALESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEV 810
N K A +ES DDL K + + + + P+ E+ V V
Sbjct: 821 NVK----APLFVESTDDLADYLKYLPMMTRLTEAQQVAALPESEDAPVAV 866
>sp|O84304|SYV_CHLTR VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437659|pir||H71532 valine--tRNA ligase (EC 6.1.1.9)
- Chlamydia trachomatis (serotype D, strain UW3/Cx)
>gi|3328717|gb|AAC67895.1| (AE001302) Valyl tRNA
Synthetase [Chlamydia trachomatis]
Length = 939
Score = 357 bits (907), Expect = 3e-97
Identities = 241/756 (31%), Positives = 362/756 (47%), Gaps = 70/756 (9%)
Query: 3 PKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDI 62
PK YDP E +W ++ KP+Y+I PPP +G LH+GH L +T D
Sbjct: 7 PKAYDPKSSETGVYSFWERSGMFVANASSEKPAYSIVMPPPNVTGILHMGHALVNTLQDT 66
Query: 63 IARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGI------TKDQPEEFLKKCVEWTWQA 116
+ RYKRM+G+ V + G D+ G+ T+ VE+ T EEFLK +W ++
Sbjct: 67 LIRYKRMQGFEVCWVPGTDHAGIATQTVVERHLKASLGKQRTDFSREEFLKHVWDWKEKS 126
Query: 117 IEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRT 176
+ Q ++G S DW + TMD AV+K+ + KG+IYR + V W P +T
Sbjct: 127 QNVILSQLRQLGCSCDWSRQRFTMDPGANRAVKKAFKILFDKGVIYRGYYLVNWDPILQT 186
Query: 177 SLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVG 236
+LA EV Y E +G+LYYI+ + + +I +ATTRPE + A+ V P+D RY HL+G
Sbjct: 187 ALADDEVEYEERDGWLYYIRYQVVNSEEFITVATTRPETLLGDTAIAVSPEDLRYSHLIG 246
Query: 237 KKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTM 296
KV +P RE+PI+ D VD +FGTGAV D+ D + LP+I + G +
Sbjct: 247 AKVVVPFVNREIPIIGDFSVDASFGTGAVKITPAHDKDDYKTGMNHQLPMINILTPTGEI 306
Query: 297 NENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQW 356
NEN G + GL E AR+ I LE +GL KKE RV + RS A IE KQW
Sbjct: 307 NENGGIFTGLSREVARENIITSLEALGLFVKKEAYSSRV-GVSYRSG--AIIEPYLSKQW 363
Query: 357 FIRVKDFTDEI--VKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCK 414
F+ V F D + ++EI +P + W ++ DW ISRQ +G P W K
Sbjct: 364 FVSVDSFRDSLRGFVNSEEIRIFPPEFVRNYLTWVNNLK-DWCISRQLWWGHRIPVWHNK 422
Query: 415 NG-HIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEA 473
+ ++I E P + D + P DVLD W S + PL W +
Sbjct: 423 HDENVICFDGEGGPEEVMRDPESWYQDP----------DVLDTWFSSGLWPLTCFGWPD- 471
Query: 474 IKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPD 533
+ + KK+ +PTA+ G DI+ W + + +P+ D+ ++G++ G
Sbjct: 472 -ENSLDLKKF----YPTAVLVTGHDILFFWVTRMVLMCSAMVDTEPFSDVFLHGLIFGKS 526
Query: 534 GR----------------------------------KMSKSYGNVVAPDEVIPKYGADAL 559
R K+SKS GNV+ P E+I YGADA+
Sbjct: 527 YREYDEKGEWFYVSGERKRDYDKGKALPKNVVAKWEKLSKSKGNVIDPIEMIEAYGADAV 586
Query: 560 RL-WTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDF---DYEKYKDIELEP 615
RL + A GE + + F+ K+WN RF HI + D E+ + +L
Sbjct: 587 RLTLCSCANRGEQIDLDYHLFEEYKNFINKLWNGARFIFGHISELTSRDLEEGVNQDLLG 646
Query: 616 L-DRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYG--DDE 672
L D +IL R + ++ Y F+ I F +++ Y+E++K L+G D +
Sbjct: 647 LEDFYILDRFNELLDLIDGHYNCYSFDKIASLAYDFFKNDLCSTYLEIIKPTLFGKQDSD 706
Query: 673 ESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAM 708
+ + + L LL N++ +L P VP+ITE ++ +
Sbjct: 707 QQRATKRKLLATLLINILGVLHPIVPYITETLFQKL 742
>pir||E82001 valyl-tRNA synthetase NMA0094 [imported] - Neisseria meningitidis
(group A strain Z2491) >gi|7378867|emb|CAB83410.1|
(AL162752) valyl-tRNA synthetase [Neisseria meningitidis
Z2491]
Length = 945
Score = 355 bits (902), Expect = 1e-96
Identities = 259/858 (30%), Positives = 398/858 (46%), Gaps = 111/858 (12%)
Query: 5 KYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIA 64
KY P EIE K + W E+ ++ +D KPS++I PPP +GTLH+GH + T +D +
Sbjct: 4 KYSPAEIESKHYQNWEEQGYFQPDMDLTKPSFSIQLPPPNVTGTLHMGHAFNQTIMDGLT 63
Query: 65 RYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQ-----PEEFLKKCVEWTWQAIEA 119
RY RM+G N + G D+ G+ T++ VE++ E+FL+K EW +
Sbjct: 64 RYYRMKGCNTAWIPGTDHAGIATQIVVERQLAAQNVSRHDLGREKFLEKVWEWKEVSGGT 123
Query: 120 MRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLA 179
+ +Q R+G SADW EY TMDD V + + Y++GLIYR + V W P T+++
Sbjct: 124 ITQQMRRVGCSADWTREYFTMDDVRAETVTEVFVRLYEQGLIYRGKRLVNWDPVLGTAVS 183
Query: 180 KAEVGYVEEEGYLYYIKLPLADG-SGYIPIATTRPELMPACVAVFVHPDDERYKHLVGKK 238
EV VEE+G +++I+ PLAD + + +ATTRPE + VAV V+P+DERY HL+GK+
Sbjct: 184 DLEVESVEEQGSMWHIRYPLADNPAEAVIVATTRPETLLGDVAVAVNPEDERYTHLIGKE 243
Query: 239 VKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNE 298
+ LP+ R +P++ADE V+ +FGTG V D D KR++ ++ + + +
Sbjct: 244 LILPLTGRTIPVIADEYVEKDFGTGCVKITPAHDFNDYEVGKRHDTRLVNVFDLEAKVLA 303
Query: 299 NA----------------GPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERS 342
NA YAGL ARK++ DL++ G L +IK L +
Sbjct: 304 NAEVFNFKGEAQPSFALPEKYAGLDRFAARKQMVADLQEQGFLV---EIKAHTLMTPKGD 360
Query: 343 SCMAPIELLPKKQWFIRVK---------------DFTDEIVKVAKE--INWYPEDMFLRL 385
+ IE + QWF+ + D+ K + + PE+
Sbjct: 361 RTGSVIEPMLTSQWFVAMSATPNGGEPDSEFKGLSLADKAKKAVDSGAVRFIPENWVNTY 420
Query: 386 KDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVDPRFDKPPVEKCPVCGA 445
W ++ DW ISRQ +G P W G++ AR ++ + + K + +
Sbjct: 421 NQWMNNIQ-DWCISRQLWWGHQIPAWYDNEGNVYVARNQE-EAEKQAGKTGLTR------ 472
Query: 446 EIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAF 505
DVLD W S++ P W +E K + P+ + G +II W
Sbjct: 473 ----EEDVLDTWFSSALVPFSTLGWPSE---TDELKAF----LPSNVLVTGYEIIFFWVA 521
Query: 506 YTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAP------------------ 547
I T TGK P+KD+ I+G+V +G+KMSKS GNV+ P
Sbjct: 522 RMIMMTTHFTGKVPFKDVYIHGIVRDHEGKKMSKSEGNVIDPVDLIDGIDLEKLLVKRTT 581
Query: 548 -------------------DEVIPKYGADALRLWTA-LAPPGEDHPFKWETVDYNFRFLQ 587
E IP GADALR A A G F ++ + F
Sbjct: 582 GLRKPETAPKVEEASRKLFPEGIPSMGADALRFTMASYASLGRSVNFDFKRAEGYRNFCN 641
Query: 588 KVWNIYRFAERHIKDFDYEKYKDIELEPL-----DRWILSRLHRIIKFATEELERYRFNL 642
K+WN F + ++ D Y EP D WI+ RL++ I+ T+ E YRF+L
Sbjct: 642 KIWNATNFVLMNTENQDC-GYGATATEPRGYSFPDMWIVDRLNQTIEQVTQAYETYRFDL 700
Query: 643 ITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITE 702
L +F+W++ D Y+E+ K +L + + L +L + LL P +P ITE
Sbjct: 701 AAETLYSFMWNDYCDWYLELAKVQLQTGCASRQRATRHTLLRVLEAALRLLHPIIPFITE 760
Query: 703 EIYH--AMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPL 760
E++ A D S+ L +PE I + A + + + ++ +R + G+
Sbjct: 761 ELWQTVAPMCDAKTADSIMLARFPEADSGEIVQTAFEQMTVLQDLIGAVRNLRGEMGIQP 820
Query: 761 NAKLEHVAIYALESYDDL 778
N K A +ES DDL
Sbjct: 821 NVK----APLFVESTDDL 834
>pir||G81348 valine--tRNA ligase (EC 6.1.1.9) Cj0775c [imported] - Campylobacter
jejuni (strain NCTC 11168) >gi|6968221|emb|CAB73040.1|
(AL139076) valyl-tRNA synthetase [Campylobacter jejuni]
Length = 870
Score = 354 bits (899), Expect = 2e-96
Identities = 272/887 (30%), Positives = 436/887 (48%), Gaps = 61/887 (6%)
Query: 6 YDPNEIEPKWQKYWLEEKIYKYRLDENKP------SYAIDTPPPFTSGTLHLGHVLSHTW 59
YD N +E ++ + EE+ Y + +D NK ++ I PPP +G LH+GH L+ T
Sbjct: 2 YDKN-LEKEYYQI-CEERGY-FEIDGNKTIQEKDKNFCIMMPPPNVTGVLHIGHALTFTL 58
Query: 60 IDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEF---GITKDQ--PEEFLKKCVEWTW 114
DI+ RYKRM GY VL+ G D+ G+ T+ VEK+ GI K++ EEF++K EW
Sbjct: 59 QDIMTRYKRMDGYKVLYQPGLDHAGIATQNVVEKQLLTQGIKKEELGREEFIEKVWEWKE 118
Query: 115 QAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKC 174
Q+ + Q +G + W TMD+ AV+K+ +E Y K LI R + + WC
Sbjct: 119 QSGGKILDQMRTLGITPAWSRLRFTMDEGLVNAVKKAFVELYDKRLIVRGNYMINWCTH- 177
Query: 175 RTSLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHL 234
+L+ EV Y E +G LY+IK L D ++ +ATTRPE AV VHPDDERY
Sbjct: 178 DGALSDIEVEYKENKGKLYHIKYFLKDSDEFLVVATTRPETFFGDTAVMVHPDDERYAKF 237
Query: 235 VGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDG 294
V K+V LPI ++ + I+AD+ V+ FGTG V D D R+NL I +E G
Sbjct: 238 VDKEVILPISKKAIKIIADKHVEKEFGTGVVKVTPAHDMNDYEVGLRHNLDFISVFDEKG 297
Query: 295 TMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKK 354
+NE+ + GL+ EAR+KI LE +G + K E+ +++ + R C +E K
Sbjct: 298 ILNEHCLEFQGLERLEAREKIVAKLESLGFIEKIEEYNNQI-GYCYR--CNNIVEPYISK 354
Query: 355 QWFIRVKDFTDEIVKVA-KEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVC 413
QWF++ + + I KVA E +YP W + + DW ISRQ +G P + C
Sbjct: 355 QWFVKKEIAQESIEKVALGESKFYPNHWINSFNAWMKDLR-DWCISRQLWWGHQIPVYYC 413
Query: 414 KNGHIIPAREEDLPVDPRFDKPPVEKCPVCGAE-IEPVTDVLDCWVDSSITPLIITRWHE 472
+ H ++ + CP C ++ + DVLD W S + + W
Sbjct: 414 ECSHEWASQHTP------------KTCPKCQSQNFKQDEDVLDTWFSSGLWAMSTLGWGN 461
Query: 473 AIKGDEE--AKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVA 530
G ++ ++K + +P +L G DI+ W +F++ + + P+KDI ++ +V
Sbjct: 462 ENWGKDKIWSEKDLKDFYPNSLLITGFDILFFWVARMMFQSTNVLHQLPFKDIYLHALVK 521
Query: 531 GPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTA-LAPPGEDHPFKWETVDYNFRFLQKV 589
GRKMSKS GNV+ P+E I +Y AD LR A LA G D + + F K+
Sbjct: 522 DEQGRKMSKSLGNVIDPNESIKEYSADILRFTLALLAIQGRDIKLSNDKLLQVRNFTNKI 581
Query: 590 WNIYRFAERHIKDFDYEKYKDIEL-EPLDRWILSRLHRIIKFATEELERYRFNLITRELM 648
+N + + + +E ++I L L ++I ++ +K E L+ YRFN L
Sbjct: 582 YNAKNYL--LLNESKFEDLENITLHSELAKYIYAKFQTCVKDVRENLDNYRFNDAANTLY 639
Query: 649 TFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAM 708
F W + D IE+ K E+S +K ++++ + LL PF+P I+E +YH +
Sbjct: 640 KFFWDDFCDWGIELSK------AEKSSVKELGSIFK---EALKLLNPFMPFISEYLYHKL 690
Query: 709 FKDKI-GEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLE-- 765
++ S+ + +P+++E D+ EK+ L + + +R+ K+ + N+K+E
Sbjct: 691 SDTELKTSPSIMISKYPKFKEQ--DKNIEKIFSLLIESIVSIRRAKSLIDLG-NSKIEKA 747
Query: 766 HVAIYALESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLV 825
++ + D++K I E++E E +L + I +V N + +
Sbjct: 748 YIKFNDKKIKDEIKAYMNFIIMLAKCEQIEF--SEEKLPKAICDVSENLEIFITLENVDL 805
Query: 826 PRIVEHLKNNAESIAREIKENGKVEFEIDGEK--VELTKEDVMIKKE 870
I+ L+N + KE+ K+ + EK KE V KE
Sbjct: 806 SGILTRLENQKNKLE---KESFKLNSMLSNEKFIANAPKEVVEQNKE 849
>sp|O53175|SYV_MYCTU VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437648|pir||G70863 probable valS protein -
Mycobacterium tuberculosis (strain H37RV)
>gi|2791488|emb|CAA16025.1| (AL021246) valS
[Mycobacterium tuberculosis]
Length = 876
Score = 352 bits (894), Expect = 9e-96
Identities = 249/779 (31%), Positives = 377/779 (47%), Gaps = 56/779 (7%)
Query: 1 MLPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWI 60
MLPK +DP +E + WL+ + KP+Y+I PPP +G+LH+GH L HT +
Sbjct: 1 MLPKSWDPAAMESAIYQKWLDAGYFTADPTSTKPAYSIVLPPPNVTGSLHMGHALEHTMM 60
Query: 61 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEE-----FLKKCVEWTWQ 115
D + R KRM+GY VL+ G D+ G+ T+ VE++ + E+ F+ K +W +
Sbjct: 61 DALTRRKRMQGYEVLWQPGTDHAGIATQSVVEQQLAVDGKTKEDLGRELFVDKVWDWKRE 120
Query: 116 AIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCR 175
+ A+ Q R+G DW + TMD+ AV+ Y GLIYR E V W P +
Sbjct: 121 SGGAIGGQMRRLGDGVDWSRDRFTMDEGLSRAVRTIFKRLYDAGLIYRAERLVNWSPVLQ 180
Query: 176 TSLAKAEVGYVEEEGYLYYIKL-PLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHL 234
T+++ EV Y + EG L + L D +I +ATTR E M A+ VHPDDERY+HL
Sbjct: 181 TAISDLEVNYRDVEGELVSFRYGSLDDSQPHIVVATTRVETMLGDTAIAVHPDDERYRHL 240
Query: 235 VGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDG 294
VG + P +RE+ I+ADE VDP FGTGAV D D R+ LP+ ++ G
Sbjct: 241 VGTSLAHPFVDRELAIVADEHVDPEFGTGAVKVTPAHDPNDFEIGVRHQLPMPSILDTKG 300
Query: 295 TMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKK 354
+ + + G+ EAR + + L G + ++++ + H+ERS PIE
Sbjct: 301 RIVDTGTRFDGMDRFEARVAVRQALAAQGRVVEEKRPYLHSVGHSERSG--EPIEPRLSL 358
Query: 355 QWFIRVKDFTDEIVKVAK--EINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWV 412
QW++RV+ + + +P M R W + M DW ISRQ +G P W
Sbjct: 359 QWWVRVESLAKAAGDAVRNGDTVIHPASMEPRWFSWVDDMH-DWCISRQLWWGHRIPIWY 417
Query: 413 CKNGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHE 472
+G E + V P ++ P G E +P DVLD W S++ P W
Sbjct: 418 GPDG-------EQVCVGP-------DETPPQGWEQDP--DVLDTWFSSALWPFSTLGW-- 459
Query: 473 AIKGDEEAKKWFEHNFPTALRPQGTDIIRTW-AFYTIFRTF-------KLTGKK----PW 520
D+ A+ E +PT++ G DI+ W A +F TF L G++ P+
Sbjct: 460 ---PDKTAE--LEKFYPTSVLVTGYDILFFWVARMMMFGTFVGDDAAITLDGRRGPQVPF 514
Query: 521 KDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTAL-APPGEDHPFKWETV 579
D+ ++G++ GRKMSKS GNV+ P + + +GADALR A A PG D + V
Sbjct: 515 TDVFLHGLIRDESGRKMSKSKGNVIDPLDWVEMFGADALRFTLARGASPGGDLAVSEDAV 574
Query: 580 DYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYR 639
+ F K++N R+A + EL DRWIL RL + + Y
Sbjct: 575 RASRNFGTKLFNATRYALLN-GAAPAPLPSPNELTDADRWILGRLEEVRAEVDSAFDGYE 633
Query: 640 FNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPH 699
F+ L F W E D Y+E+ K +L + L L ++ LL P +P
Sbjct: 634 FSRACESLYHFAWDEFCDWYLELAKTQL----AQGLTHTTAVLAAGLDTLLRLLHPVIPF 689
Query: 700 ITEEIYHAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGM 758
+TE ++ A+ G +S+ WPE +D A + +K+V+E+R++++ G+
Sbjct: 690 LTEALWLAL----TGRESLVSADWPEPSGISVDLVAAQRINDMQKLVTEVRRFRSDQGL 744
>pir||E82913 valyl-tRNA synthetase UU267 [imported] - Ureaplasma urealyticum
>gi|6899238|gb|AAF30676.1|AE002123_9 (AE002123)
valyl-tRNA synthetase [Ureaplasma urealyticum]
Length = 874
Score = 348 bits (884), Expect = 1e-94
Identities = 231/768 (30%), Positives = 383/768 (49%), Gaps = 55/768 (7%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
L KKY E+E +W E ++K +++ K + I PPP +G LH+GH T D
Sbjct: 5 LSKKYSFKEVEANKLLFWQENNLFKAQINSTKKPFTIVLPPPNVTGHLHIGHAYDFTLSD 64
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCVEWTWQ 115
I+ RYK+++GY+ G D+ G+ T+ K EK + E FL+K W +
Sbjct: 65 ILMRYKKLKGYDSFIIPGTDHAGIATQTKFEKNLKVNAQTNRFNLGRELFLEKLKIWKDE 124
Query: 116 AIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCR 175
I + KQ+ +G D+ T+D V++ ++ + + +IYR++ V W + +
Sbjct: 125 QINYIHKQWNALGLGLDYSNYLFTLDPIVVQTVREVFVKMFNEHIIYRDKKLVNWDIQLK 184
Query: 176 TSLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLV 235
T+++ EV + E E LYYIK D ++ +AT+RPE M + ++P D+RY HL
Sbjct: 185 TAISNIEVIHKEVEQKLYYIKYLSQDQKDFVVVATSRPETMFGDKYLVINPKDKRYFHLH 244
Query: 236 GKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGT 295
K PI E+ ++ D+ +D FGTG + D D K++NL +I +N DGT
Sbjct: 245 NKIFINPINNIEMTVILDDYIDIEFGTGVMKCTPAHDFNDYELAKKHNLEIINIMNADGT 304
Query: 296 MNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQ 355
+NE G + GL EAR I + L+K L K E + V +ER++ + +E Q
Sbjct: 305 LNEKCGEFKGLDRLEARSLIIDKLQKNNHLLKVESYRTSV-GFSERTNEI--VEPYLSHQ 361
Query: 356 WFIRVKDFTDEIVKVAKEIN----WYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFW 411
WFI++ + +K+ + N +YP L W ++ + DW ISRQ +G P W
Sbjct: 362 WFIKMDSLIKDTIKMQDDCNNKVDFYPNRFNKTLLTWLKNTE-DWCISRQLWWGHQIPVW 420
Query: 412 VCKNGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWH 471
K + I + P+ + ++ DVLD W S + PL+ T+W+
Sbjct: 421 YHKKTNQIYCD----TIPPKDLENWIQD-----------EDVLDTWFSSGMWPLLTTKWN 465
Query: 472 EAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAG 531
+F+ FPT+L G DI+ W + + L KKP+KD++I+G++
Sbjct: 466 -------YNSHFFDRYFPTSLIVTGMDILFFWVSRMMNFSQYLVEKKPFKDVLIHGLIRD 518
Query: 532 PDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPP-GEDHPFKWETVDYNFRFLQKVW 590
GRKMSKS GN + P ++I KYG DA+RL+ A GED F E + N+ +L K+W
Sbjct: 519 SQGRKMSKSLGNGIDPFDIIDKYGLDAMRLFFASCTTIGEDLNFSTERLGANWNYLNKIW 578
Query: 591 NIYRFAERHIKDFDYEKYKDIE-LEPLDRWILSRLHRIIKFATEELERYRFNLITRELMT 649
NI ++ E + D ++D++ +++WIL+ L ++ + +++Y + T+ L
Sbjct: 579 NIAKYIENLDEINDNLNFEDVDKFCDVNKWILTELSKLTLEINKNMDKYNLVVATKYLYD 638
Query: 650 FIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMF 709
FIW+ A Y+E K L D K + + + ++++L PF P+I+EEI+ +
Sbjct: 639 FIWNTFASYYLEYTKVLL--QDLTLKNETIKTIRYVFNKILIMLQPFAPNISEEIWLCLN 696
Query: 710 KDKIGEKSVHLLSWP----EYREDRIDEKAEKLGELARKVVSEMRKYK 753
+ S+ L +P E+ ID+ A K++ E+RK +
Sbjct: 697 QT---NNSILLQEYPIINFEFETIIIDKIA--------KIILEIRKLR 733
>sp|O51680|SYV_BORBU VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437647|pir||A70192 valine--tRNA ligase (EC 6.1.1.9)
valS - Lyme disease spirochete
>gi|2688666|gb|AAC67078.1| (AE001173) valyl-tRNA
synthetase (valS) [Borrelia burgdorferi]
Length = 875
Score = 339 bits (859), Expect = 1e-91
Identities = 232/773 (30%), Positives = 392/773 (50%), Gaps = 41/773 (5%)
Query: 4 KKYDPNEIEPKWQKYWLEEKIYKYRLDENK--PSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+KYDP E + WL+ ++ L +N +++ PPP +G LH+GH L+ D
Sbjct: 7 EKYDPKAFEDEIYTKWLKNNVF---LPDNSLFEKFSMVAPPPNVTGVLHMGHALNFVLQD 63
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVE---KEFGITKD--QPEEFLKKCVEWTWQA 116
++ RYKRM+ +N L+ G D+ G+ T+ E K+ G +KD + EE +++ + +
Sbjct: 64 VLVRYKRMKRHNTLWLFGTDHAGIATQAVFERHLKKIGKSKDDFEREELVQEIFKLKDRH 123
Query: 117 IEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRT 176
+ Q ++G S D E T+D+ AV K + Y KGLIYR E+ V P +
Sbjct: 124 RGIIVNQINKLGASYDHSRERFTLDENLCKAVNKVFKDLYFKGLIYRGEYLVNLDPGSGS 183
Query: 177 SLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVG 236
++ E+ Y E +G LY++K D S +I +ATTRPE M A+ V+P+DERYK LVG
Sbjct: 184 VVSDEEIEYKEVDGKLYFVKY-FIDNSSFIEVATTRPETMFGDTAIAVNPNDERYKSLVG 242
Query: 237 KKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTM 296
K+V +P+ +++ ++AD VD FGTGA+ D D KR+N+ + + +DG +
Sbjct: 243 KEVTIPLTTKKIKVIADFYVDSAFGTGALKVTPAHDPNDFEISKRHNISKVNILTQDGKL 302
Query: 297 NENAG-PYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQ 355
N+N Y GL ++AR KI +L + G L +K K +V H RS IE Q
Sbjct: 303 NKNVPLQYQGLSAKDARFKIETELMEKGFLQDVKKHKQQV-GHCYRSG--EVIEPYLSTQ 359
Query: 356 WFIRVKDFTDEIVKVAK--EINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVC 413
WF+R+K D+ +K + E+ +YP+ K W ++ DW ISRQ V+G P W
Sbjct: 360 WFVRMKPLADKALKALENGELKFYPKKWENTYKYWLSNIR-DWCISRQLVWGHRIPVWYN 418
Query: 414 KNGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEA 473
+ + + DP D+ + G DVLD W S + P W
Sbjct: 419 VDTSELIVSD----TDPSLDEKNM------GKRFVQDPDVLDTWFSSWLWPFSSLGWPNV 468
Query: 474 IKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPD 533
D + F++ +PT DII W + + TG+ P+KD+ I ++
Sbjct: 469 ---DVD----FKNYYPTNTLITAYDIIFFWVARMVMAGLEFTGQVPFKDVYITPLLRDKQ 521
Query: 534 GRKMSKSYGNVVAPDEVIPKYGADALRLWTA-LAPPGEDHPFKWETVDYNFRFLQKVWNI 592
G+KMSKS GN + P ++I +YG+D+LR + L+ G+D + + +F KV+N
Sbjct: 522 GKKMSKSLGNGIDPLDIINEYGSDSLRFTLSFLSVQGQDLNIDAKDFMFGAKFANKVFNA 581
Query: 593 YRFAERHIKDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIW 652
+F ++K + + D++ +D+W+L+ L+ I Y++N ++ + F W
Sbjct: 582 SKFILLNLK--NRKILNDLKFNDIDKWLLTSLNSTILGVESSFANYKYNEASKFVYEFFW 639
Query: 653 HEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDK 712
++ D YIE+ K L ++ + + A L L +L+L PF+P +TE+IY + F +K
Sbjct: 640 NDFCDWYIEISKIDLNNENVDIQNMAISKLLFFLKKSLLILHPFIPFVTEKIY-SEFAEK 698
Query: 713 IGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLE 765
E + L +P + ++ ++ ++ + + +R K+ +P + +++
Sbjct: 699 --EDILALNEYPNFDIANNFQEEFEIFKVLKTFIIAIRTLKSEFNIPASVEID 749
>gb|AAG20324.1| (AE005106) isoleucyl-tRNA synthetase; IleS [Halobacterium sp.
NRC-1]
Length = 1070
Score = 336 bits (852), Expect = 8e-91
Identities = 263/972 (27%), Positives = 424/972 (43%), Gaps = 124/972 (12%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDE--NKPSYAIDTPPPFTSGTLHLGHVLSHTW 59
+P +YDP +E + YW Y+ +D + ++ PP+TSG H+G + T
Sbjct: 7 VPDQYDPAGVEERVFSYWEAVDAYEQTVDHRADAETFFFVDGPPYTSGAAHMGTTWNKTL 66
Query: 60 IDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCVEWT 113
D RY RM+GY+V G+D HGLP E KVE++ G + E F+++C +
Sbjct: 67 KDAYIRYHRMQGYDVTDRPGYDMHGLPIETKVEEQLGFESKKDIQEFGEEAFIEECKRFA 126
Query: 114 WQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPK 173
++ ++ F G DWD Y T+D Y A + E + GL+ R + + CP+
Sbjct: 127 DDNLDGLQSDFQSFGVWMDWDNPYKTVDPSYMEAAWWAFSEVHDNGLVERGQRSISQCPR 186
Query: 174 CRTSLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPD------ 227
C T++A EV Y + Y++ L D G + + TT P +PA V V D
Sbjct: 187 CETAIANNEVEYEDVTDPSIYVRFDLDDREGSLVVWTTTPWTIPANQFVAVDEDGDYQQV 246
Query: 228 -----------------------------------DERYKHLVGKKVKLPIYEREV--PI 250
D L+G P+ + P
Sbjct: 247 RATTPDGETDVLYVASECVEDVLSAGGYSDHEIVADHSGSDLIGWSYTPPLADAVPANPT 306
Query: 251 LADEDVDPNFG-------TGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPY 303
AD + G TG V++ E+D +LPV + EDG + G Y
Sbjct: 307 DADGTHEVYHGDWVEADRTGLVHSAPGHGEEDFERGAELDLPVFCPVGEDGVYTDAGGKY 366
Query: 304 AGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDF 363
AG V +A I DLE + + ++H H R C I + QWFI + D
Sbjct: 367 AGAFVRDANDDIIADLEARDAMLASQTVEHSY-GHCWR--CDTGIIQIVTDQWFITITDV 423
Query: 364 TDEIVKVAKEINWYPE-DMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGH----- 417
DE++ W+PE R +D+ E+ DW +SRQR +G P P W ++
Sbjct: 424 KDELLANMDTSEWHPEWARDNRFRDFVENAP-DWNVSRQRYWGIPVPIWTPEDWSGDAED 482
Query: 418 --IIPAREE-----DLPVDPR---FDKPPVEKCPVC--GAEIEPVTDVLDCWVDSSITPL 465
++ REE D VDP KP V+ + G E V DV D W+DSS+
Sbjct: 483 VLVVGTREELAALADQDVDPASVDLHKPTVDDITITEDGTEYTRVPDVFDVWLDSSVAS- 541
Query: 466 IITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVI 525
W ++E F+ +P L + D R W + + G P++++++
Sbjct: 542 ----WGTLNYPEQEDD--FDELWPADLIMEAHDQTRGWFWSQLGMGTAALGDVPYEEVLM 595
Query: 526 NGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLW-TALAPPGEDHPFKWETVDYNFR 584
+G PDGR MSKS G + P+EVI +YGAD +R++ ++ P G+D F W+ + R
Sbjct: 596 HGYANMPDGRGMSKSKGITIEPNEVIDEYGADPMRMFLLSVTPQGDDMSFSWDETENMQR 655
Query: 585 FLQKVWNIYRFAERH--IKDFDYE------------KYKDIELEPLDRWILSRLHRIIKF 630
L +WN++RF + + DFD D +LE +D W+LSRL +
Sbjct: 656 DLNILWNVFRFPRPYMALDDFDANVPAAFGGDDAGVGIADADLETVDEWLLSRLQHVKAD 715
Query: 631 ATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDD-EESKLKAKVALYELLYNV 689
AT E + + ++ F+ +++ Y+++V+ R++ DD SK A + +L V
Sbjct: 716 ATAHWEDFEQHRALDAVLEFVVEDLSRYYVQVVRERMWEDDASASKTAAYATMQRVLLEV 775
Query: 690 MLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYRED----------RIDEKAEKLG 739
+ LLAP+ P +TEE+Y + D+ G +VH+ WP E + AE+ G
Sbjct: 776 VALLAPYAPFVTEELYSHLTGDR-GYDTVHMADWPTVEESLRAPALEADVAVLRAAEEAG 834
Query: 740 ELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESYDDLKLIEKDIAGTMNIEKLEIFKG 799
AR+ RK + + E + AL+++ DL +A +N +E+ +
Sbjct: 835 SHARQQAG--RKLRWPVTRVVVDAAEDSVVDALDAHGDL------LADRLNTRAIEVVEP 886
Query: 800 EPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKNNAESIAREIKENG-KVEFEIDGEKV 858
+E + + +GP +G ++ L N+A R+I +V ++ + +
Sbjct: 887 GAAWDELAYSARADMSELGPAFGDDAGAVMNAL-NDARVTDRDIDALAEQVAADLGRDDI 945
Query: 859 ELTKEDVMIKKE 870
ELT E V +E
Sbjct: 946 ELTTEMVEFVEE 957
>sp|P07118|SYV_ECOLI VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7428469|pir||SYECVT valine--tRNA ligase (EC 6.1.1.9)
- Escherichia coli (strain K-12)
>gi|1790708|gb|AAC77215.1| (AE000496) valine tRNA
synthetase [Escherichia coli K12]
Length = 951
Score = 333 bits (844), Expect = 7e-90
Identities = 267/965 (27%), Positives = 435/965 (44%), Gaps = 120/965 (12%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+ K Y+P +IE ++W ++ +K DE++ S+ I PPP +G+LH+GH T +D
Sbjct: 1 MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMD 60
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCVEWTWQ 115
+ RY+RM+G N L+ G D+ G+ T++ VE++ + + E F+ K EW +
Sbjct: 61 TMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAE 120
Query: 116 AIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCR 175
+ + +Q R+G S DW+ E TMD+ AV++ + YK+ LIYR + V W PK R
Sbjct: 121 SGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLR 180
Query: 176 TSLAKAEVGYVEEEGYLYYIKLPLADGS------GYIPIATTRPELMPACVAVFVHPDDE 229
T+++ EV E +G +++I+ PLADG+ Y+ +ATTRPE + V V+P+D
Sbjct: 181 TAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDP 240
Query: 230 RYKHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIA 289
RYK L+GK V LP+ R +PI+ DE D GTG V D D KR+ LP+I
Sbjct: 241 RYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINI 300
Query: 290 INEDGTMNENAG----------------PYAGLKVEE--ARKKIAEDLEKMGLLYKKEKI 331
+ DG + E+A P K+E ARK + ++ +GLL E+I
Sbjct: 301 LTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLL---EEI 357
Query: 332 KHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAK--EINWYPEDMFLRLKDWA 389
K L IE + QW++R V+ + +I + P+ W
Sbjct: 358 KPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWM 417
Query: 390 ESMDWDWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEI-- 447
+ DW ISRQ +G P W + G++ R ED V K GA++
Sbjct: 418 RDIQ-DWCISRQLWWGHRIPAWYDEAGNVYVGRNED----------EVRKENNLGADVVL 466
Query: 448 EPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYT 507
DVLD W S++ W E + +A + F PT++ G DII W
Sbjct: 467 RQDEDVLDTWFSSALWTFSTLGWPE----NTDALRQFH---PTSVMVSGFDIIFFWIARM 519
Query: 508 IFRTFKL----TGKK--PWKDIVINGMVAGPDGRKMSKSYGNVVAPDEV----------- 550
I T GK P+ + + G++ +G+KMSKS GNV+ P ++
Sbjct: 520 IMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLE 579
Query: 551 --------------------------IPKYGADALRLW-TALAPPGEDHPFKWETVDYNF 583
I +G DALR ALA G D + + ++
Sbjct: 580 KRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYR 639
Query: 584 RFLQKVWNIYRFAERHIKDFDYE-KYKDIELEPLDRWILSRLHRIIKFATEELERYRFNL 642
F K+WN RF + + D ++ L DRWIL+ ++ IK E L+ +RF++
Sbjct: 640 NFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDI 699
Query: 643 ITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITE 702
L F W++ D Y+E+ K + G E + L +L ++ L P +P ITE
Sbjct: 700 AAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITE 759
Query: 703 EIYHAM-FKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKN----SHG 757
I+ + I ++ L +P+Y ++DE A E ++ + +R + + G
Sbjct: 760 TIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPG 819
Query: 758 MPLNAKLEHVAIYALESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRI 817
PL L + A ++ + + +A +E + + + + + ++ + +
Sbjct: 820 KPLELLLRGCSADAERRVNENRGFLQTLA---RLESITVLPADDKGPVSVTKIIDGAELL 876
Query: 818 GPRYGKLVPRIVEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVMIKKE---VFSE 874
P G L N + +AR KE K+E EI + +L E + + + E
Sbjct: 877 IPMAG---------LINKEDELARLAKEVAKIEGEISRIENKLANEGFVARAPEAVIAKE 927
Query: 875 GERVE 879
E++E
Sbjct: 928 REKLE 932
>emb|CAA29322.1| (X05891) valyl-tRNA synthetase [Escherichia coli]
Length = 951
Score = 333 bits (844), Expect = 7e-90
Identities = 267/965 (27%), Positives = 435/965 (44%), Gaps = 120/965 (12%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+ K Y+P +IE ++W ++ +K DE++ S+ I PPP +G+LH+GH T +D
Sbjct: 1 MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMD 60
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCVEWTWQ 115
+ RY+RM+G N L+ G D+ G+ T++ VE++ + + E F+ K EW +
Sbjct: 61 TMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAE 120
Query: 116 AIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCR 175
+ + +Q R+G S DW+ E TMD+ AV++ + YK+ LIYR + V W PK R
Sbjct: 121 SGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLR 180
Query: 176 TSLAKAEVGYVEEEGYLYYIKLPLADGS------GYIPIATTRPELMPACVAVFVHPDDE 229
T+++ EV E +G +++I+ PLADG+ Y+ +ATTRPE + V V+P+D
Sbjct: 181 TAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDP 240
Query: 230 RYKHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIA 289
RYK L+GK V LP+ R +PI+ DE D GTG V D D KR+ LP+I
Sbjct: 241 RYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINI 300
Query: 290 INEDGTMNENAG----------------PYAGLKVEE--ARKKIAEDLEKMGLLYKKEKI 331
+ DG + E+A P K+E ARK + ++ +GLL E+I
Sbjct: 301 LTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLL---EEI 357
Query: 332 KHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAK--EINWYPEDMFLRLKDWA 389
K L IE + QW++R V+ + +I + P+ W
Sbjct: 358 KPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWM 417
Query: 390 ESMDWDWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEI-- 447
+ DW ISRQ +G P W + G++ R ED V K GA++
Sbjct: 418 RDIQ-DWCISRQLWWGHRIPAWYDEAGNVYVGRNED----------EVRKENNLGADVVL 466
Query: 448 EPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYT 507
DVLD W S++ W E + +A + F PT++ G DII W
Sbjct: 467 RQDEDVLDTWFSSALWTFSTLGWPE----NTDALRQFH---PTSVMVSGFDIIFFWIARM 519
Query: 508 IFRTFKL----TGKK--PWKDIVINGMVAGPDGRKMSKSYGNVVAPDEV----------- 550
I T GK P+ + + G++ +G+KMSKS GNV+ P ++
Sbjct: 520 IMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLE 579
Query: 551 --------------------------IPKYGADALRLW-TALAPPGEDHPFKWETVDYNF 583
I +G DALR ALA G D + + ++
Sbjct: 580 KRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYR 639
Query: 584 RFLQKVWNIYRFAERHIKDFDYE-KYKDIELEPLDRWILSRLHRIIKFATEELERYRFNL 642
F K+WN RF + + D ++ L DRWIL+ ++ IK E L+ +RF++
Sbjct: 640 NFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDTFRFDI 699
Query: 643 ITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITE 702
L F W++ D Y+E+ K + G E + L +L ++ L P +P ITE
Sbjct: 700 AAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITE 759
Query: 703 EIYHAM-FKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKN----SHG 757
I+ + I ++ L +P+Y ++DE A E ++ + +R + + G
Sbjct: 760 TIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPG 819
Query: 758 MPLNAKLEHVAIYALESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRI 817
PL L + A ++ + + +A +E + + + + + ++ + +
Sbjct: 820 KPLELLLRGCSADAERRVNENRGFLQTLA---RLESITVLPADDKGPVSVTKIIDGAELL 876
Query: 818 GPRYGKLVPRIVEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVMIKKE---VFSE 874
P G L N + +AR KE K+E EI + +L E + + + E
Sbjct: 877 IPMAG---------LINKEDELARLAKEVAKIEGEISRIENKLANEGFVARAPEAVIAKE 927
Query: 875 GERVE 879
E++E
Sbjct: 928 REKLE 932
>gb|AAA97155.1| (U14003) valyl-tRNA synthetase [Escherichia coli]
Length = 951
Score = 333 bits (844), Expect = 7e-90
Identities = 267/965 (27%), Positives = 435/965 (44%), Gaps = 120/965 (12%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+ K Y+P +IE ++W ++ +K DE++ S+ I PPP +G+LH+GH T +D
Sbjct: 1 MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMD 60
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCVEWTWQ 115
+ RY+RM+G N L+ G D+ G+ T++ VE++ + + E F+ K EW +
Sbjct: 61 TMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAE 120
Query: 116 AIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCR 175
+ + +Q R+G S DW+ E TMD+ AV++ + YK+ LIYR + V W PK R
Sbjct: 121 SGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLR 180
Query: 176 TSLAKAEVGYVEEEGYLYYIKLPLADGS------GYIPIATTRPELMPACVAVFVHPDDE 229
T+++ EV E +G +++I+ PLADG+ Y+ +ATTRPE + V V+P+D
Sbjct: 181 TAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDP 240
Query: 230 RYKHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIA 289
RYK L+GK V LP+ R +PI+ DE D GTG V D D KR+ LP+I
Sbjct: 241 RYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINI 300
Query: 290 INEDGTMNENAG----------------PYAGLKVEE--ARKKIAEDLEKMGLLYKKEKI 331
+ DG + E+A P K+E ARK + ++ +GLL E+I
Sbjct: 301 LTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLL---EEI 357
Query: 332 KHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAK--EINWYPEDMFLRLKDWA 389
K L IE + QW++R V+ + +I + P+ W
Sbjct: 358 KPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWM 417
Query: 390 ESMDWDWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEI-- 447
+ DW ISRQ +G P W + G++ R ED V K GA++
Sbjct: 418 RDIQ-DWCISRQLWWGHRIPAWYDEAGNVYVGRNED----------EVRKENNLGADVVL 466
Query: 448 EPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYT 507
DVLD W S++ W E + +A + F PT++ G DII W
Sbjct: 467 RQDEDVLDTWFSSALWTFSTLGWPE----NTDALRQFH---PTSVMVSGFDIIFFWIARM 519
Query: 508 IFRTFKL----TGKK--PWKDIVINGMVAGPDGRKMSKSYGNVVAPDEV----------- 550
I T GK P+ + + G++ +G+KMSKS GNV+ P ++
Sbjct: 520 IMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLE 579
Query: 551 --------------------------IPKYGADALRLW-TALAPPGEDHPFKWETVDYNF 583
I +G DALR ALA G D + + ++
Sbjct: 580 KRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYR 639
Query: 584 RFLQKVWNIYRFAERHIKDFDYE-KYKDIELEPLDRWILSRLHRIIKFATEELERYRFNL 642
F K+WN RF + + D ++ L DRWIL+ ++ IK E L+ +RF++
Sbjct: 640 NFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDXFRFDI 699
Query: 643 ITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITE 702
L F W++ D Y+E+ K + G E + L +L ++ L P +P ITE
Sbjct: 700 AAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITE 759
Query: 703 EIYHAM-FKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKN----SHG 757
I+ + I ++ L +P+Y ++DE A E ++ + +R + + G
Sbjct: 760 TIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPG 819
Query: 758 MPLNAKLEHVAIYALESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRI 817
PL L + A ++ + + +A +E + + + + + ++ + +
Sbjct: 820 KPLELLLRGCSADAERRVNENRGFLQTLA---RLESITVLPADDKGPVSVTKIIDGAELL 876
Query: 818 GPRYGKLVPRIVEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVMIKKE---VFSE 874
P G L N + +AR KE K+E EI + +L E + + + E
Sbjct: 877 IPMAG---------LINKEDELARLAKEVAKIEGEISRIENKLANEGFVARAPEAVIAKE 927
Query: 875 GERVE 879
E++E
Sbjct: 928 REKLE 932
>gb|AAA24657.1| (J03497) valyl tRNA synthetase [Escherichia coli]
Length = 951
Score = 331 bits (840), Expect = 2e-89
Identities = 272/965 (28%), Positives = 435/965 (44%), Gaps = 120/965 (12%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+ K Y+P +IE ++W ++ +K DE++ S+ I PPP +G+LH+GH T +D
Sbjct: 1 MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMD 60
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCVEWTWQ 115
+ RY+RM+G N L+ G D+ G+ T++ VE++ + + E F+ K EW +
Sbjct: 61 TMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGAEAFIDKIWEWKAE 120
Query: 116 AIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCR 175
+ + +Q R+G S DW+ E TMD+ AV++ + YK+ LIYR + V W PK R
Sbjct: 121 SGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLR 180
Query: 176 TSLAKAEVGYVEEEGYLYYIKLPLADGS------GYIPIATTRPELMPACVAVFVHPDDE 229
T+++ EV E +G +++I+ PLADG+ Y+ +ATTRPE + V V+P+D
Sbjct: 181 TAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDP 240
Query: 230 RYKHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIA 289
RYK L+GK V LP+ R +PI+ DE D GTG V D D KR+ LP+I
Sbjct: 241 RYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINI 300
Query: 290 INEDGTMNENAG----------------PYAGLKVEE--ARKKIAEDLEKMGLLYKKEKI 331
+ DG + E+A P K+E ARK + ++ +GLL E+I
Sbjct: 301 LTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLL---EEI 357
Query: 332 KHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAK--EINWYPEDMFLRLKDWA 389
K L IE + QW++R V+ + +I + P+ W
Sbjct: 358 KPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWM 417
Query: 390 ESMDWDWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEI-- 447
+ DW ISRQ +G P W + G++ R ED V K GA++
Sbjct: 418 RDIQ-DWCISRQLWWGHRIPAWYDEAGNVYVGRNED----------EVRKENNLGADVVL 466
Query: 448 EPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYT 507
DVLD W S++ W E + +A + F PT++ G DII W
Sbjct: 467 RQDEDVLDTWFSSALWTFSTLGWPE----NTDALRQFH---PTSVMVSGFDIIFFWIARM 519
Query: 508 IFRTFKL----TGKK--PWKDIVINGMVAGPDGRKMSKSYGNVVAPDEV----------- 550
I T GK P+ + + G++ +G+KMSKS GNV+ P ++
Sbjct: 520 IMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLE 579
Query: 551 --------------------------IPKYGADALRLW-TALAPPGEDHPFKWETVDYNF 583
I +G DALR ALA G D + + ++
Sbjct: 580 KRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYR 639
Query: 584 RFLQKVWNIYRFAERHIKDFDYE-KYKDIELEPLDRWILSRLHRIIKFATEELERYRFNL 642
F K+WN RF + + D ++ L DRWIL+ ++ IK E L+ +RF++
Sbjct: 640 NFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDI 699
Query: 643 ITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITE 702
L F W++ D Y+E+ K + G E + L +L ++ L P +P ITE
Sbjct: 700 AAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITE 759
Query: 703 EIYHAM-FKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKN----SHG 757
I+ + I ++ L +P+Y ++DE A E ++ + +R + + G
Sbjct: 760 TIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPG 819
Query: 758 MPLNAKLEHVAIYALESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRI 817
PL L S D + + ++ + +LE P ++ V V +I
Sbjct: 820 KPLELLLRGC------SADRERRVNENRGFLQTLARLESITVLPADDKGPVSV----TKI 869
Query: 818 GPRYGKLVPRIVEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVMIKKE---VFSE 874
L+P + L N + +AR KE K+E EI + +L E + + + E
Sbjct: 870 IDGAELLIP--MAGLINKEDELARLAKEVAKIEGEISRIENKLANEGFVARAPEAVIAKE 927
Query: 875 GERVE 879
E++E
Sbjct: 928 REKLE 932
>dbj|BAB06264.1| (AP001515) isoleucyl-tRNA synthetase [Bacillus halodurans]
Length = 921
Score = 330 bits (836), Expect = 6e-89
Identities = 230/786 (29%), Positives = 371/786 (46%), Gaps = 90/786 (11%)
Query: 8 PNEIEPKWQKYWLEEKIYK--YRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIAR 65
PN EP+ Q+ W + IY+ + +P + + PP+ +G +H+GH L+ D+I R
Sbjct: 21 PNR-EPQMQEEWKDMNIYEKVQARTKGRPLFVLHDGPPYANGDIHMGHALNKVLKDMIVR 79
Query: 66 YKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPE--EFLKKCVEWTWQAIEAMRKQ 123
YK M G++ + G+D HGLP E + K G+ + EF K C E+ + I+ R+Q
Sbjct: 80 YKSMAGFHAPYVPGWDTHGLPIEQALTKS-GVDRKSMSVAEFRKLCEEFARKQIDRQREQ 138
Query: 124 FIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV 183
F+R+G DW Y T+D ++A K E KKG IY+ + PVYW P ++LA+AE+
Sbjct: 139 FMRLGVRGDWWNPYVTLDKGFEAQQVKVFGEMAKKGYIYKGKKPVYWSPSSESALAEAEI 198
Query: 184 GYVEEEGYLYYIKLPLADGSGY------IPIATTRPELMPACVAVFVHPD---------D 228
Y ++ Y+ P+ DG I I TT P +PA + + VHP+
Sbjct: 199 EYHDKRSPSIYVAFPVKDGKNVLQQDEKIVIWTTTPWTIPANLGIAVHPELEYSVVAVKG 258
Query: 229 ERYKHLVG--------------------KKVKL-------PIYEREVPILADEDVDPNFG 261
E+Y G K V L PIY R+ ++ + V + G
Sbjct: 259 EKYVVASGLVETLESALEWENPEILRTIKGVDLEYVVAEHPIYGRDSLVVLGDHVTLDAG 318
Query: 262 TGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEK 321
TG V+ E+D + ++Y L V+ +++ G M A + GL +EA K I + L++
Sbjct: 319 TGCVHTAPGHGEEDYIVGQKYGLDVLCPVDDKGYMTAEAPGFEGLFYDEANKPITQKLDE 378
Query: 322 MGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDM 381
G L K I H H R+ P+ QWF +++F DE+++ +E+ W PE
Sbjct: 379 CGALLKLTFITHS-YAHDWRTK--KPVIYRATAQWFASIENFRDELLRAIQEVKWVPEWG 435
Query: 382 FLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVDPRFDKP------ 435
RL + DW ISRQRV+G P P + +NG I E V F K
Sbjct: 436 ETRLYNMVRDRG-DWCISRQRVWGVPIPIFYGENGEPIITDETINHVSELFRKHGSNVWF 494
Query: 436 ------------PVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKW 483
E P + D++D W DS + H+ + + E
Sbjct: 495 EWETKDLLPEGFTHESSP--NGQFTREMDIMDVWFDSGSS-------HQGVLVERE---- 541
Query: 484 FEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGN 543
E + P L +G+D R W ++ + +TGK P+K ++ +G +G+KMSKS GN
Sbjct: 542 -ELDRPADLYLEGSDQYRGWFNSSLSTSVAITGKAPYKGVLSHGFTLDGEGKKMSKSLGN 600
Query: 544 VVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDF 603
VV P++V+ + GAD LRLW A D + + +K+ N YRF ++ DF
Sbjct: 601 VVIPNDVMKQLGADILRLWVASVDYQADVRVSDKILKQVSEVYRKIRNTYRFLLGNLHDF 660
Query: 604 DYEKYKDI--ELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIE 661
++ +L LDR++L++L+ +I + + Y+F+ + EL F E++ Y++
Sbjct: 661 HPATHRVAIDQLNGLDRYMLAKLNDVINRVKKAYDEYQFSTVYHELHNFCTIELSSFYMD 720
Query: 662 MVKYRLY--GDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVH 719
+ K LY D + + +Y++L + LL+P +PH +E++ + + E+SV
Sbjct: 721 IAKDTLYVKHADHPDRRATQTVMYDVLVALAKLLSPIIPHTADEVWKHI--PGVEEESVQ 778
Query: 720 LLSWPE 725
L PE
Sbjct: 779 LTDMPE 784
>sp|Q45477|SYI_BACSU ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437553|pir||H69643 isoleucine--tRNA ligase (EC
6.1.1.5) ileS - Bacillus subtilis
>gi|2633916|emb|CAB13417.1| (Z99112) isoleucyl-tRNA
synthetase [Bacillus subtilis]
Length = 921
Score = 329 bits (834), Expect = 1e-88
Identities = 238/832 (28%), Positives = 375/832 (44%), Gaps = 95/832 (11%)
Query: 8 PNEIEPKWQKYWLEEKIYKYRLDENK--PSYAIDTPPPFTSGTLHLGHVLSHTWIDIIAR 65
PN EP QK W EE IY+ + K P + + PP+ +G +H+GH L+ D I R
Sbjct: 21 PNR-EPDIQKKWEEEDIYRLVQERTKDRPKFVLHDGPPYANGDIHMGHALNKILKDFIVR 79
Query: 66 YKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPE--EFLKKCVEWTWQAIEAMRKQ 123
YK M GYN + G+D HGLP E + K + + + EF K C E+ W+ IE R+Q
Sbjct: 80 YKSMSGYNAPYVPGWDTHGLPIETALTKNKKVNRKEMSVAEFRKLCEEYAWKQIEGQREQ 139
Query: 124 FIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV 183
F R+G DW+ Y T+ Y+A + E K+G IY+ PV W P ++LA+AE+
Sbjct: 140 FKRLGVRGDWENPYVTLKPEYEAQQIRVFGEMAKRGYIYKGLKPVNWSPSSESALAEAEI 199
Query: 184 GYVEEEGYLYYIKLPLADGSGY------IPIATTRPELMPACVAVFVHPD---------D 228
Y ++ Y+ + DG G I I TT P +PA + + VHPD +
Sbjct: 200 EYQDKRSASIYVAFGVKDGKGVLENGERIIIWTTTPWTIPANLGISVHPDLEYSVIAVGE 259
Query: 229 ERY---------------------------KHLVGKKVKLPIYEREVPILADEDVDPNFG 261
+R+ K L + P+Y R+ ++ E V + G
Sbjct: 260 DRFVVASALVENVASACGFDQYEVTRTVKGKDLENIIAEHPLYGRDSLVMLGEHVTTDAG 319
Query: 262 TGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEK 321
TG V+ E D + ++Y L V+ ++E G M A + G+ ++A K I + L++
Sbjct: 320 TGCVHTAPGHGEDDFIIGQKYGLDVLCPVDEKGVMTSEAPGFEGMFYDDANKAITQQLDE 379
Query: 322 MGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDM 381
G L K E I H H R+ P QWF +KDF +++ KE W PE
Sbjct: 380 KGALVKLEFITHS-YPHDWRTK--KPTIFRATAQWFASIKDFRSDLLDAIKETKWVPEWG 436
Query: 382 FLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVDPR---------F 432
RL + DW ISRQR +G P P + +NG + E V F
Sbjct: 437 EQRLHNMVRDRG-DWCISRQRAWGVPIPVFYAENGEPVITDETIEHVSELFRQHGSNIWF 495
Query: 433 DKPPVEKCP-------VCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFE 485
+K + P D++D W DS + H+A+ + + +
Sbjct: 496 EKEAKDLLPEGFTHPGSPNGTFTKEQDIMDVWFDSGSS-------HQAVLEERD-----D 543
Query: 486 HNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVV 545
P L +G+D R W ++ +TGK P+K ++ +G +GRKMSKS GNVV
Sbjct: 544 LVRPADLYLEGSDQYRGWFNSSLSTAVAVTGKAPYKGVLSHGFALDGEGRKMSKSIGNVV 603
Query: 546 APDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDFDY 605
P +V+ + GAD LRLW + D + +K+ N +RF ++ DFD
Sbjct: 604 VPAKVMKQLGADILRLWVSSVDYQADVRVSDAILKQVAEVYRKIRNTFRFLHGNLFDFD- 662
Query: 606 EKYKDIELEPL---DRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEM 662
K + +E L D+++L +L+++I + + Y F ++ + F E++ Y++
Sbjct: 663 PKTNAVAVEDLREVDQYMLIKLNKLIDKVKKAYDEYEFAVVYHSIHNFCTIELSSFYLDF 722
Query: 663 VKYRLYGD--DEESKLKAKVALYELLYNVMLLLAPFVPHITEEIY-HAMFKDKIGEKSVH 719
K +Y + D + + YE L ++ L AP +PH +E++ H F + E+SV
Sbjct: 723 AKDIVYIEHADHPDRRSMQTVSYETLLALVKLSAPILPHTADELWSHLTF---VEEQSVQ 779
Query: 720 LLSWPEY----REDRIDEKAEKLGELARKVVSEMRKYKNSH--GMPLNAKLE 765
L PE + +EK ++ L V+ + +N G L A L+
Sbjct: 780 LTDMPETITVPNSEATEEKFDRFMALRDDVLKALETARNEKIIGKSLEANLK 831
>pir||T39630 valine-tRNA ligase precursor, mitochondrial - fission yeast
(Schizosaccharomyces pombe) >gi|7493608|pir||T39665
valine-tRNA ligase precursor, mitochondrial - fission
yeast (Schizosaccharomyces pombe)
>gi|3738140|emb|CAA21241.1| (AL031852) valyl-trna
synthetase, mitochondrial [Schizosaccharomyces pombe]
>gi|3738176|emb|CAA21312.1| (AL031856) valyl-trna
synthetase, mitochondrial precursor [Schizosaccharomyces
pombe]
Length = 980
Score = 328 bits (833), Expect = 1e-88
Identities = 272/876 (31%), Positives = 397/876 (45%), Gaps = 119/876 (13%)
Query: 4 KKYDPNEIEPKWQKYWLEEKIYKYRLD-ENKPS----YAIDTPPPFTSGTLHLGHVLSHT 58
K Y+P +E W +W++ ++ + KP + I +PPP +G LH+GH L+
Sbjct: 95 KSYNPKAVESAWYDWWVKSGFFEPEFGPDGKPKKEGVFVITSPPPNVTGALHIGHALTIA 154
Query: 59 WIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITK-----DQP-EEFLKKCVEW 112
D +AR+ RM G VLF GFD+ GL T+ VEK+ T+ D P ++F+ EW
Sbjct: 155 IQDSLARWNRMLGKTVLFLGGFDHAGLSTQSVVEKKLWYTQKKTRHDYPRDKFVDIVWEW 214
Query: 113 TWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCP 172
+ ++ Q R+G S DW E TMD+ AV ++ + +++ +IYR V WC
Sbjct: 215 KEEYHNRIKNQMSRLGGSFDWTREAFTMDENLSRAVVETFVRLHEENIIYRANRLVNWCT 274
Query: 173 KCRTSLAKAEV--------------GYVE--EEGYLYYIKLPLADGSGYIPIATTRPELM 216
+T+L+ EV GY E E G L I + I IATTRPE +
Sbjct: 275 ALQTTLSNLEVENVDVPGRTLLKVPGYDEPVEVGVLTSIAYAVEGSDERIVIATTRPETL 334
Query: 217 PACVAVFVHPDDERYKHLVGKKVKLPIYEREVPILADED-VDPNFGTGAVYNCTYGDEQD 275
AV VHP D RYKHL GK VK P R +PI+ D+ VD FGTGAV D D
Sbjct: 335 LGDTAVAVHPQDPRYKHLHGKFVKHPFCNRSIPIICDDIIVDMEFGTGAVKITPAHDPND 394
Query: 276 IVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRV 335
KR+NL I +DG +NEN G +AG+K AR K+ E L+++GL + K V
Sbjct: 395 YEVGKRHNLEFINIFTDDGLLNENCGEFAGMKRFTARVKVVERLKELGL-FVGTKENPMV 453
Query: 336 LRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAK--EINWYPEDMFLRLKDWAESMD 393
+ ++S + IE + K QW++ K+ +V K EI P+ W E++
Sbjct: 454 IPLCGKTSDI--IEPVMKPQWWVNQKEMAAAAAEVVKSGEIEIAPDMSRREFIRWMENIQ 511
Query: 394 WDWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVDPRFDKPP-------------VEKC 440
DW ISRQ +W GH IPA +L +P D+ EK
Sbjct: 512 -DWCISRQL-------WW----GHRIPAYFVNLADEPSQDRSEGRYWVTGRTLEQAEEKA 559
Query: 441 ----PVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQG 496
P +E DVLD W S + P W + +E+ +PT L G
Sbjct: 560 KAAFPGKSFTLEQDEDVLDTWFSSGLWPFSTLGWPKDTSD-------YENFYPTTLMETG 612
Query: 497 TDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEV------ 550
DI+ W + KLTGK P+K + + +V GRKMSKS GNVV P +V
Sbjct: 613 WDILFFWIARMVMLGLKLTGKIPFKRVFCHALVRDAQGRKMSKSLGNVVDPIDVIEGISL 672
Query: 551 -------------------------------IPKYGADALRL-WTALAPPGEDHPFKWET 578
IP+ G DALR +L G D
Sbjct: 673 QALHDKLLVGNLDSREVEKAKKGQRLSYPKGIPQCGTDALRFTLCSLTTGGRDLNLDILR 732
Query: 579 VDYNFRFLQKVWNIYRFAERHI-KDFDYEKYKDI--ELEPLDRWILSRLHRIIKFATEEL 635
V+ +F K++N +FA + +F K D+ +++WI RL+ + +
Sbjct: 733 VEGYRKFCNKLYNATKFALGRLGSNFVPNKTADLTGNESLVEKWIFHRLNIAAAAMNKNM 792
Query: 636 ERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAP 695
E F T + F +E+ D YIE KY L E + AK LY +L N + L+ P
Sbjct: 793 EEMNFLQATSAVHQFWLYELCDVYIENSKYLLSDGTEVQQESAKQTLYTVLDNALRLMHP 852
Query: 696 FVPHITEEIYHAMFKDKIGEKSVHLL--SWPEYREDRIDEKAEKLGELARKVVSEMRKYK 753
F+P++TEE++ + + + G+K+ ++ ++P R D +E A K E VV R
Sbjct: 853 FMPYVTEEMWQRLPR-RPGDKTQTIVKAAFPVERVDYSNEIAAKYYESIITVVHSTRSMM 911
Query: 754 NSHGMPLNAKL------EHVAIYALESYDDLKLIEK 783
+G+ +A + EH + ES LI+K
Sbjct: 912 AENGIKSDAVVYIHPDEEHSKLITSESASIQSLIKK 947
>sp|P93736|SYV_ARATH VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|1890130|gb|AAB49704.1| (U89986) valyl tRNA synthetase
[Arabidopsis thaliana]
Length = 1107
Score = 327 bits (830), Expect = 3e-88
Identities = 286/984 (29%), Positives = 439/984 (44%), Gaps = 144/984 (14%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+ K+Y P +E W +W + ++K +KP + I PPP +G LH+GH L+ D
Sbjct: 136 MAKQYSPATVEKSWYAWWEKSDLFKADAKSSKPPFVIVLPPPNVTGALHIGHALTSAIED 195
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEF----GITKDQP--EEFLKKCVEWTWQ 115
I R+KRM GYN L+ G D+ G+ T++ VEK+ G+T+ EEF+K+ +W Q
Sbjct: 196 TIIRWKRMSGYNALWVPGVDHAGIATQVVVEKKIMRDRGMTRHDVGREEFVKEVWKWKNQ 255
Query: 116 AIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCR 175
+ Q R+G S DW E TMD+ AV ++ + YK+GLIYR+ V W R
Sbjct: 256 YGGTILTQLRRLGASLDWSRECFTMDEQRSKAVTEAFVRLYKEGLIYRDIRLVNWDCILR 315
Query: 176 TSLAKAEVGYVE----------------EEGYLYYIKLPLADGSGYIPIATTRPELMPAC 219
T+++ EV Y++ E G L PL + G + +ATTR E M
Sbjct: 316 TAISDVEVEYIDIKEKTLLKVPGYEKPVEFGLLTSFAYPLEE-LGRVIVATTRVETMLGD 374
Query: 220 VAVFVHPDDERYKHLVGKKVKLPIYEREVPILADED-VDPNFGTGAVYNCTYGDEQDIVW 278
A+ +HPDD RYKHL GK P R++PI+ D VDPNFGTG V D D
Sbjct: 375 TAIAIHPDDARYKHLHGKFAVHPFNGRKLPIICDGILVDPNFGTGCVKITPAHDPNDCEV 434
Query: 279 QKRYNLPVIIAINEDGTMNENAGP-YAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLR 337
KR+ L I +DG +N N G +AG+ AR+ + E L+K GL Y+ K L
Sbjct: 435 GKRHKLEFINIFTDDGKINTNGGSDFAGMPRFAAREAVVEALQKQGL-YRGAKNNEMRLG 493
Query: 338 HTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVA-----KEINWYPEDMFLRLKDWAESM 392
R++ + IE + K QW++ E + VA K++ + P+ + W E++
Sbjct: 494 LCSRTNDV--IEPMIKPQWYVNCSMXGKEALDVAITDENKKLEFVPKQYTAEWRRWLENI 551
Query: 393 DWDWVISRQRVFGTPFPFWVCK------------NGHIIPAREEDLPVDPRFDKPPVEKC 440
DW ISRQ +G P W + H + AR ED D R + +K
Sbjct: 552 R-DWCISRQLWWGHRIPAWYATLEEDQLKEVGAYSDHWVVARTED---DAR--EEAAQKF 605
Query: 441 PVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDII 500
E+ DVLD W S + PL + W + F+ +PT++ G DI+
Sbjct: 606 LGKKFELTRDPDVLDTWFSSGLFPLSVLGWPDVTDD-------FKAFYPTSVLETGHDIL 658
Query: 501 RTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVI--------- 551
W + KL G+ P+ + + M+ GRKMSKS GNV+ P EVI
Sbjct: 659 FFWVARMVMMGMKLGGEVPFSKVYFHPMIRDAHGRKMSKSLGNVIDPLEVINGVTLGGLH 718
Query: 552 ----------------------------PKYGADALR--LWTALAPPGEDHPFKWETVDY 581
P+ G DALR L + A + + V Y
Sbjct: 719 KRLEEGNLDPKEVIVAKEGQVKDFPNGIPECGTDALRFALVSYTAQSDKINLDILRVVGY 778
Query: 582 NFRFLQKVWNIYRFAERHIKDFDYEKYKDIELEPLD---RWILSRLHRIIKFATEELERY 638
++ K+WN RFA + Y + + E + +WILS L++ I A L+ +
Sbjct: 779 R-QWCNKLWNAVRFAMMKLGS-GYTPPQTLSPETMPFSCQWILSVLNKAISKAVVSLDAF 836
Query: 639 RFNLITRELMTFIWHEVADDYIEMVKYRLYGDD---EESKLKAKVALYELLYNVMLLLAP 695
F+ + + ++ D YIE +K GD+ + A+ AL+ L + LL P
Sbjct: 837 EFSDAANTIYAWWQYQFCDVYIEAIKPYFAGDNPTFASERAHAQHALWISLETGLRLLHP 896
Query: 696 FVPHITEEIYHAM--FKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYK 753
F+P +TEE++ + KD + S+ + +P E+ +EK E + V MR +
Sbjct: 897 FMPFVTEELWQRLPAPKDTERKASIMICDYPSAIENWSNEKVESEMDTVLATVKCMRALR 956
Query: 754 NSHGMPLNAKLEHVAIYAL----ESYDDLKLIEKDIAGTMNIEKLEIF-KGEPQLEERIV 808
G+ K E + +AL + + +K E +I N+ LE+ KG+
Sbjct: 957 --AGLLEKQKNERLPAFALCENNVTSEIVKSHELEIRTLANLSSLEVVSKGQHAAPP--- 1011
Query: 809 EVKPNYKRIGPRYGKLVPRIVEHLKNNAESIAREIKENGKVEFEIDGEKV-----ELTKE 863
G V + E+LK +K +G + E + EK+ EL K+
Sbjct: 1012 -------------GSSVETVNENLK-------VYLKVDGAINTEAEQEKIRNKIGELQKQ 1051
Query: 864 DVMIKK--EVFSEGERVETAVVDD 885
++K VF+ E+V + +D
Sbjct: 1052 KEKLQKMMSVFTYEEKVPANIKED 1075
>gb|AAF63175.1|AC010657_11 (AC010657) T5E21.11 [Arabidopsis thaliana]
Length = 1115
Score = 326 bits (828), Expect = 5e-88
Identities = 266/894 (29%), Positives = 404/894 (44%), Gaps = 119/894 (13%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHT--- 58
+ K+Y P +E W +W + ++K +KP + I PPP +G LH+GH L+
Sbjct: 136 MAKQYSPATVEKSWYAWWEKSDLFKADAKSSKPPFVIVLPPPNVTGALHIGHALTSAIEV 195
Query: 59 ----WIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEF----GITKDQP--EEFLKK 108
+D I R+KRM GYN L+ G D+ G+ T++ VEK+ G+T+ EEF+K+
Sbjct: 196 SLAYCLDTIIRWKRMSGYNALWVPGVDHAGIATQVVVEKKIMRDRGMTRHDVGREEFVKE 255
Query: 109 CVEWTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPV 168
+W Q + Q R+G S DW E TMD+ AV ++ + YK+GLIYR+ V
Sbjct: 256 VWKWKNQYGGTILTQLRRLGASLDWSRECFTMDEQRSKAVTEAFVRLYKEGLIYRDIRLV 315
Query: 169 YWCPKCRTSLAKAEVGYVE----------------EEGYLYYIKLPLADGSGYIPIATTR 212
W RT+++ EV Y++ E G L PL G G + +ATTR
Sbjct: 316 NWDCILRTAISDVEVEYIDIKEKTLLKVPGYEKPVEFGLLTSFAYPLEGGLGEVIVATTR 375
Query: 213 PELMPACVAVFVHPDDERYKHLVGKKVKLPIYEREVPILADED-VDPNFGTGAVYNCTYG 271
E M A+ +HPDD RYKHL GK P R++PI+ D VDPNFGTG V
Sbjct: 376 VETMLGDTAIAIHPDDARYKHLHGKFAVHPFNGRKLPIICDGILVDPNFGTGCVKITPAH 435
Query: 272 DEQDIVWQKRYNLPVIIAINEDGTMNENAG-PYAGLKVEEARKKIAEDLEKMGLLYKKEK 330
D D KR+ L I +DG +N N G +AG+ AR+ + E L+K G LY+ K
Sbjct: 436 DPNDCEVGKRHKLEFINIFTDDGKINTNGGSDFAGMPRFAAREAVVEALQKQG-LYRGAK 494
Query: 331 IKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVA-----KEINWYPEDMFLRL 385
L R++ + IE + K QW++ E + VA K++ + P+
Sbjct: 495 NNEMRLGLCSRTNDV--IEPMIKPQWYVNCSMIGKEALDVAITDENKKLEFVPKQYTAEW 552
Query: 386 KDWAESMDWDWVISRQRVFGTPFPFWVCK------------NGHIIPAREEDLPVDPRFD 433
+ W E++ DW ISRQ +G P W + H + AR ED D R
Sbjct: 553 RRWLENIR-DWCISRQLWWGHRIPAWYATLEEDQLKEVGAYSDHWVVARTED---DAR-- 606
Query: 434 KPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALR 493
+ +K E+ DVLD W S + PL + W + F+ +PT++
Sbjct: 607 EEAAQKFLGKKFELTRDPDVLDTWFSSGLFPLSVLGWPDVTDD-------FKAFYPTSVL 659
Query: 494 PQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEV--- 550
G DI+ W + KL G+ P+ + + M+ GRKMSKS GNV+ P EV
Sbjct: 660 ETGHDILFFWVARMVMMGMKLGGEVPFSKVYFHPMIRDAHGRKMSKSLGNVIDPLEVING 719
Query: 551 ----------------------------------IPKYGADALR--LWTALAPPGEDHPF 574
IP+ G DALR L + A + +
Sbjct: 720 VTLEGLHKRLEEGNLDPKEVIVAKEGQVKDFPNGIPECGTDALRFALVSYTAQSDKINLD 779
Query: 575 KWETVDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIELEPLD---RWILSRLHRIIKFA 631
V Y ++ K+WN RFA + D Y + + E + +WILS L++ I
Sbjct: 780 ILRVVGYR-QWCNKLWNAVRFAMMKLGD-GYTPPQTLSPETMPFSCQWILSVLNKAISKT 837
Query: 632 TEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDD---EESKLKAKVALYELLYN 688
L+ + F+ + + ++ D YIE +K GD+ + A+ AL+ L
Sbjct: 838 VVSLDAFEFSDAANTIYAWWQYQFCDVYIEAIKPYFAGDNPTFASERAHAQHALWISLET 897
Query: 689 VMLLLAPFVPHITEEIYHAM--FKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVV 746
+ LL PF+P +TEE++ + KD + S+ + +P E+ +EK E + V
Sbjct: 898 GLRLLHPFMPFVTEELWQRLPAPKDTERKASIMICDYPSAIENWSNEKVESEMDTVLATV 957
Query: 747 SEMRKYKNSHGMPLNAKLEHVAIYAL----ESYDDLKLIEKDIAGTMNIEKLEI 796
MR + G+ K E + +AL + + +K E +I N+ LE+
Sbjct: 958 KCMRALR--AGLLEKQKNERLPAFALCENNVTSEIVKSHELEIRTLANLSSLEV 1009
>sp|O51773|SYI_BORBU ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437557|pir||H70203 isoleucine--tRNA ligase (EC
6.1.1.5) ileS - Lyme disease spirochete
>gi|2688775|gb|AAC67179.1| (AE001181) isoleucyl-tRNA
synthetase (ileS) [Borrelia burgdorferi]
Length = 1042
Score = 326 bits (826), Expect = 9e-88
Identities = 253/938 (26%), Positives = 430/938 (44%), Gaps = 94/938 (10%)
Query: 10 EIEPKWQKYWLEEKIYKYRLDENK--PSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYK 67
+IE K K+W + KI++ + + + + PPF +G H GH + +T DII RY+
Sbjct: 13 KIEEKILKFWNDNKIFEKSIKQREGCEEFTFYDGPPFATGLPHFGHFVPNTIKDIIPRYQ 72
Query: 68 RMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCVEWTWQAIEAMR 121
M+G V G+D HGLP E +VEK+ GI+ E F K+C + + E +
Sbjct: 73 TMQGKYVKRNFGWDTHGLPVEYEVEKKLGISGKYEIENYGIENFNKECRKIVLRYTEEWK 132
Query: 122 KQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKA 181
+R+G D++ Y TMD + +V Y+KGLIY + + + PK T L+
Sbjct: 133 NIILRLGRWVDFEKGYKTMDISFMESVWWVFKNLYEKGLIYESYYVLPYSPKLATPLSNF 192
Query: 182 EVG---YVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKH----- 233
EV Y E IK + D + Y+ + TT P +P+ + + V + E K
Sbjct: 193 EVNLGEYKEVNDPSLTIKFKIKDKNEYLLVWTTTPWTLPSNLGIAVGQEIEYSKIFDKTK 252
Query: 234 ----LVGKKVKLPIYEREVPILADE----------DVDPNF------------------- 260
++G K Y+ E E + +P F
Sbjct: 253 EEILILGSKKLNSYYDDENSYTIIEKFKGSKLEGIEYEPIFNYFLEQKDKGAFKVHTADY 312
Query: 261 -----GTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKI 315
GTG V+ +G+E + +K N+ +I ++ + + GL V++A KKI
Sbjct: 313 VTTDDGTGIVHIAPFGEEDYRILKKHTNVDIIDPLDAECKFTNQVKDFKGLFVKDADKKI 372
Query: 316 AEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEIN 375
E+L+ L+K+E HR R++C PI P WF+ V+ ++++V ++IN
Sbjct: 373 IENLKLRNFLFKRENYLHRY-PFCYRTNC--PIIYRPISSWFVNVEKIKTKLLEVNEKIN 429
Query: 376 WYPEDMFL-RLKDWAESMDWDWVISRQRVFGTPFPFWVC-KNG------------HIIPA 421
W P + R W E+ DW ISR R +G P P W+C K G ++
Sbjct: 430 WMPAHLKKGRFGKWLENAK-DWAISRNRFWGNPIPIWICSKTGKKICIGSKKELENLSGQ 488
Query: 422 REEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAK 481
+ EDL D + DK + G + ++VLDCW +S P + + +
Sbjct: 489 KIEDLHKD-QIDK--ITWPSKDGGKFIRTSEVLDCWFESGAMPYASNHYPFTNEIN---- 541
Query: 482 KWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSY 541
F++ FP +G D R W + L +K++++NG+V DGRKMSKS+
Sbjct: 542 --FKNIFPADFIAEGLDQTRGWFYTLTILGTALFENTAFKNVIVNGLVLSSDGRKMSKSF 599
Query: 542 GNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWE---TVDYNFRFLQKVWNIYRFAER 598
N P +VI +GADALRL+ ++P + K+ D + +WN Y F
Sbjct: 600 KNYTDPMQVINTFGADALRLYLIMSPVVKADDLKYSDNGVRDVLKNIIIPIWNAYSFFTT 659
Query: 599 HIKDFDYEKYKDIEL---EPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEV 655
+ ++ K++ L LD+WI+S L + K E+++Y L+ FI ++
Sbjct: 660 YAIIDKFKPPKNLSLAKNNNLDKWIISELESLKKILNTEIDKYNLTKSIESLLEFI-DKL 718
Query: 656 ADDYIEMVKYRLY-GDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIG 714
+ YI + R + ++++ K A LY + +M+LLAPF+P ITEEIY + D+
Sbjct: 719 NNWYIRRSRRRFWKSENDKDKNDAYETLYYAIKTLMILLAPFIPFITEEIYQNLKTDE-D 777
Query: 715 EKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALES 774
++S+HL +P+ E+ I++ E+ LARK+ S R ++ H + + + + I
Sbjct: 778 KQSIHLNDYPKANENFINKTIEEKINLARKITSMARSLRSLHNIKIRMPISTIYIVTKNQ 837
Query: 775 YDDLKLIEKD--IAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHL 832
+ L+E I +N ++++I E +L + K N+K +G + GK + + +
Sbjct: 838 NEQNMLMEMQEIILDEINAKEMKIKANEEEL--ITYKAKANFKELGKKLGKDMKAVSTEI 895
Query: 833 KNNAESIAREIKENGKVEFEIDGEKVELTKEDVMIKKE 870
+I E ++ K L+ D+++++E
Sbjct: 896 SKLKNEDIIKIINGTSYEIKVANAKHYLSLNDIILERE 933
>pir||E82068 valyl-tRNA synthetase VC2503 [imported] - Vibrio cholerae (group
O1 strain N16961) >gi|9657085|gb|AAF95645.1| (AE004320)
valyl-tRNA synthetase [Vibrio cholerae]
Length = 953
Score = 326 bits (826), Expect = 9e-88
Identities = 240/848 (28%), Positives = 379/848 (44%), Gaps = 103/848 (12%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+ K Y+P IE K W E+ +K D +K +Y+I PPP +G+LH+GH T +D
Sbjct: 1 MEKTYNPTSIEQDLYKTWEEQGYFKPHGDTSKDAYSIMIPPPNVTGSLHMGHAFQDTIMD 60
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEK----EFGITKDQ--PEEFLKKCVEWTWQ 115
+ R +RM+G N L+ G D+ G+ T++ VE+ E G TK + F+ K EW +
Sbjct: 61 TLIRCQRMKGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTKHDYGRDAFIDKIWEWKAE 120
Query: 116 AIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCR 175
+ + KQ R+G S DWD E TMDD + AVQ+ + YK LIYR + V W PK
Sbjct: 121 SGGTITKQLRRLGASVDWDRERFTMDDGFYKAVQEVFVRLYKDDLIYRGKRLVNWDPKLH 180
Query: 176 TSLAKAEVGYVEEEGYLYYIKLPLADG------SGYIPIATTRPELMPACVAVFVHPDDE 229
T+++ EV E +G++++ + PLADG YI +ATTRPE M V V+P+D
Sbjct: 181 TAISDLEVENKETKGHMWHFRYPLADGVKTADGKDYIVVATTRPETMLGDTGVAVNPEDP 240
Query: 230 RYKHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIA 289
RYK L+GK++ LPI R +PI+ DE D GTG V D D KR+ LP+I
Sbjct: 241 RYKDLIGKEIILPIVGRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHQLPMINI 300
Query: 290 INEDGTMNENA------------------GPYAGLKVEEARKKIAEDLEKMGLLYKKEKI 331
+ D + + A Y G++ ARK I + E++GLL ++I
Sbjct: 301 LTFDANIRDAAEVFNSNGEASNAYGTEIPAKYQGMERFAARKAIVAEFEELGLL---QEI 357
Query: 332 KHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAK--EINWYPEDMFLRLKDWA 389
K L IE + QW++R V+ + +I + P+ W
Sbjct: 358 KDHDLTVPYGDRGGVVIEPMLTDQWYVRAGILAKPAVEAVENGDIQFVPKQYENMYFSWM 417
Query: 390 ESMDWDWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEP 449
+ DW ISRQ +G P W + G++ R E+ + E +
Sbjct: 418 RDIQ-DWCISRQLWWGHRIPAWYDEQGNVFVGRNEE--------EVRAENNIAADVALRQ 468
Query: 450 VTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIF 509
DVLD W S++ W G E + PT + G DII W I
Sbjct: 469 DDDVLDTWFSSAL-------WTFGTLGWPEKTPELKVFHPTDVLVTGFDIIFFWVARMIM 521
Query: 510 RTFKLT------GKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIP----------- 552
T + P+K + + G++ +G KMSKS GNV+ P ++I
Sbjct: 522 MTMHFCKDEDGKAQVPFKTVYVTGLIRDENGDKMSKSKGNVLDPIDMIDGIDLESLVAKR 581
Query: 553 --------------------------KYGADALRLW-TALAPPGEDHPFKWETVDYNFRF 585
YG D+LR A+A G D + + ++ F
Sbjct: 582 TGNMMQPQLAAKIEKNTRKTFENGIEAYGTDSLRFTLAAMASTGRDINWDMKRLEGYRNF 641
Query: 586 LQKVWNIYRFAERHIKDFD--YEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLI 643
K+WN R+ + ++ D + ++E D+WI S+ K ++ +R ++
Sbjct: 642 CNKLWNASRYVLMNTEEQDCGFAAGAELEYSLADKWIESQFELAAKEFNGHIDNFRLDMA 701
Query: 644 TRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEE 703
L FIW++ D Y+E+ K L+ E + + L +L + L P +P+ITE
Sbjct: 702 ANTLYEFIWNQFCDWYLELTKPVLWKGTEAQQRATRRTLITVLEKTLRLAHPVIPYITET 761
Query: 704 IYHAM--FKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMR----KYKNSHG 757
I+ ++ D + ++ L + P+Y +++A E + ++ +R +Y + G
Sbjct: 762 IWQSVKPLVDGVEGDTIMLQALPQYDVANFNQEALDDIEWVKAFITSIRNLRAEYDINPG 821
Query: 758 MPLNAKLE 765
PL L+
Sbjct: 822 KPLEVMLK 829
>gb|AAA35207.1| (J02719) valyl-tRNA synthetase [Saccharomyces cerevisiae]
Length = 1104
Score = 325 bits (824), Expect = 1e-87
Identities = 254/842 (30%), Positives = 383/842 (45%), Gaps = 96/842 (11%)
Query: 4 KKYDPNEIEPKWQKYWLEEKIYKYRLDEN---KPS--YAIDTPPPFTSGTLHLGHVLSHT 58
K Y+P +E W +W++ +++ + KP + I PPP +G LH+GH L+
Sbjct: 146 KGYNPANVESSWYDWWIKTGVFEPEFTADGKVKPEGVFCIPAPPPNVTGALHIGHALTIA 205
Query: 59 WIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP-------EEFLKKCVE 111
D + RY RM+G VLF GFD+ G+ T+ VEK+ KD+ E F+ K E
Sbjct: 206 IQDSLIRYNRMKGKTVLFLPGFDHAGIATQSVVEKQIW-AKDRKTRHDYGREAFVGKVWE 264
Query: 112 WTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWC 171
W + ++ Q ++G S DW E T+ +V+++ + + +G+IYR V W
Sbjct: 265 WKEEYHSRIKNQIQKLGASYDWSREAFTLSPELTKSVEEAFVRLHDEGVIYRASRLVNWS 324
Query: 172 PKCRTSLAKAEV--------------GYVE--EEGYLYYIKLPLADGSGYIPIATTRPEL 215
K T+++ EV GY E E G L P+ + IATTRPE
Sbjct: 325 VKLNTAISNLEVENKDVKSRTLLSVPGYDEKVEFGVLTSFAYPVIGSDEKLIIATTRPET 384
Query: 216 MPACVAVFVHPDDERYKHLVGKKVKLPIYEREVPILAD-EDVDPNFGTGAVYNCTYGDEQ 274
+ AV VHPDD+RYKHL GK ++ P R++PI+ D E VD FGTGAV D+
Sbjct: 385 IFGDTAVAVHPDDDRYKHLHGKFIQHPFLPRKIPIITDKEAVDMEFGTGAVKITPAHDQN 444
Query: 275 DIVWQKRYNLPVIIAINEDGTMNENAGP-YAGLKVEEARKKIAEDLEKMGLLYKKEKIKH 333
D KR+NL I + +DG +NE GP + G+K +ARKK+ E L++ LY ++
Sbjct: 445 DYNTGKRHNLEFINILTDDGLLNEECGPEWQGMKRFDARKKVIEQLKEKN-LYVGQEDNE 503
Query: 334 RVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAK--EINWYPEDMFLRLKDWAES 391
+ RS + IE L K QW++ + + +KV K +I P+ W +
Sbjct: 504 MTIPTCSRSGDI--IEPLLKPQWWVSQSEMAKDAIKVVKDGQITITPKSSEAEYFHWLGN 561
Query: 392 MDWDWVISRQRVFGTPFP-FWVCKNGHIIPAREEDLPVDPR----FDKPPVEKCPVCGAE 446
+ DW ISRQ +G P +++ G + D V R +K K P
Sbjct: 562 IQ-DWCISRQLWWGHRCPVYFINIEGEEHDRIDGDYWVAGRSMEEAEKKAAAKYPNSKFT 620
Query: 447 IEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFY 506
+E DVLD W S + P W E K E +P ++ G DI+ W
Sbjct: 621 LEQDEDVLDTWFSSGLWPFSTLGWPEKTKD-------METFYPFSMLETGWDILFFWVTR 673
Query: 507 TIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEV---------------- 550
I KLTG P+K++ + +V GRKMSKS GNV+ P +V
Sbjct: 674 MILLGLKLTGSVPFKEVFCHSLVRDAQGRKMSKSLGNVIDPLDVITGIKLDDLHAKLLQG 733
Query: 551 ---------------------IPKYGADALRL-WTALAPPGEDHPFKWETVDYNFRFLQK 588
IP+ G DA+R A G D V+ +F K
Sbjct: 734 NLDPREVEKAKIGQKESYPNGIPQCGTDAMRFALCAYTTGGRDINLDILRVEGYRKFCNK 793
Query: 589 VWNIYRFAERHIKDFDYEKYKDIELEP----LDRWILSRLHRIIKFATEELERYRFNLIT 644
++ +FA + D DY+ L +++WIL +L K E L++ F T
Sbjct: 794 IYQATKFALMRLGD-DYQPPATEGLSGNESLVEKWILHKLTETSKIVNEALDKRDFLTST 852
Query: 645 RELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEI 704
+ F W+ + D YIE KY + K AK LY LL N + L+ PF+P I+EE+
Sbjct: 853 SSIYEF-WYLICDVYIENSKYLIQEGSAIEKKSAKDTLYILLDNALKLIHPFMPFISEEM 911
Query: 705 YHAMFKDKIGEKSVHLL--SWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNA 762
+ + K + EK+ ++ S+P Y + D K+ +L + E R + + + N
Sbjct: 912 WQRLPK-RSTEKAASIVKASYPVYVSEYDDVKSANAYDLVLNITKEARSLLSEYNILKNG 970
Query: 763 KL 764
K+
Sbjct: 971 KV 972
>gi|6321531 mitochondrial and cytoplasmic valyl-tRNA synthetase; Vas1p
[Saccharomyces cerevisiae]
>gi|1711655|sp|P07806|SYV_YEAST VALYL-TRNA SYNTHETASE,
MITOCHONDRIAL PRECURSOR (VALINE--TRNA LIGASE) (VALRS)
>gi|2144552|pir||SYBYVT valine--tRNA ligase (EC 6.1.1.9)
- yeast (Saccharomyces cerevisiae)
>gi|1323141|emb|CAA97097.1| (Z72879) ORF YGR094w
[Saccharomyces cerevisiae]
Length = 1104
Score = 324 bits (822), Expect = 3e-87
Identities = 253/842 (30%), Positives = 383/842 (45%), Gaps = 96/842 (11%)
Query: 4 KKYDPNEIEPKWQKYWLEEKIYKYRLDEN---KPS--YAIDTPPPFTSGTLHLGHVLSHT 58
K Y+P +E W +W++ +++ + KP + I PPP +G LH+GH L+
Sbjct: 146 KAYNPANVESSWYDWWIKTGVFEPEFTADGKVKPEGVFCIPAPPPNVTGALHIGHALTIA 205
Query: 59 WIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP-------EEFLKKCVE 111
D + RY RM+G VLF GFD+ G+ T+ VEK+ KD+ E F+ K E
Sbjct: 206 IQDSLIRYNRMKGKTVLFLPGFDHAGIATQSVVEKQIW-AKDRKTRHDYGREAFVGKVWE 264
Query: 112 WTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWC 171
W + ++ Q ++G S DW E T+ +V+++ + + +G+IYR V W
Sbjct: 265 WKEEYHSRIKNQIQKLGASYDWSREAFTLSPELTKSVEEAFVRLHDEGVIYRASRLVNWS 324
Query: 172 PKCRTSLAKAEV--------------GYVE--EEGYLYYIKLPLADGSGYIPIATTRPEL 215
K T+++ EV GY E E G L P+ + IATTRPE
Sbjct: 325 VKLNTAISNLEVENKDVKSRTLLSVPGYDEKVEFGVLTSFAYPVIGSDEKLIIATTRPET 384
Query: 216 MPACVAVFVHPDDERYKHLVGKKVKLPIYEREVPILAD-EDVDPNFGTGAVYNCTYGDEQ 274
+ AV VHPDD+RYKHL GK ++ P R++PI+ D E VD FGTGAV D+
Sbjct: 385 IFGDTAVAVHPDDDRYKHLHGKFIQHPFLPRKIPIITDKEAVDMEFGTGAVKITPAHDQN 444
Query: 275 DIVWQKRYNLPVIIAINEDGTMNENAGP-YAGLKVEEARKKIAEDLEKMGLLYKKEKIKH 333
D KR+NL I + +DG +NE GP + G+K +ARKK+ E L++ LY ++
Sbjct: 445 DYNTGKRHNLEFINILTDDGLLNEECGPEWQGMKRFDARKKVIEQLKEKN-LYVGQEDNE 503
Query: 334 RVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAK--EINWYPEDMFLRLKDWAES 391
+ RS + IE L K QW++ + + +KV + +I P+ W +
Sbjct: 504 MTIPTCSRSGDI--IEPLLKPQWWVSQSEMAKDAIKVVRDGQITITPKSSEAEYFHWLGN 561
Query: 392 MDWDWVISRQRVFGTPFP-FWVCKNGHIIPAREEDLPVDPR----FDKPPVEKCPVCGAE 446
+ DW ISRQ +G P +++ G + D V R +K K P
Sbjct: 562 IQ-DWCISRQLWWGHRCPVYFINIEGEEHDRIDGDYWVAGRSMEEAEKKAAAKYPNSKFT 620
Query: 447 IEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFY 506
+E DVLD W S + P W E K E +P ++ G DI+ W
Sbjct: 621 LEQDEDVLDTWFSSGLWPFSTLGWPEKTKD-------METFYPFSMLETGWDILFFWVTR 673
Query: 507 TIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEV---------------- 550
I KLTG P+K++ + +V GRKMSKS GNV+ P +V
Sbjct: 674 MILLGLKLTGSVPFKEVFCHSLVRDAQGRKMSKSLGNVIDPLDVITGIKLDDLHAKLLQG 733
Query: 551 ---------------------IPKYGADALRL-WTALAPPGEDHPFKWETVDYNFRFLQK 588
IP+ G DA+R A G D V+ +F K
Sbjct: 734 NLDPREVEKAKIGQKESYPNGIPQCGTDAMRFALCAYTTGGRDINLDILRVEGYRKFCNK 793
Query: 589 VWNIYRFAERHIKDFDYEKYKDIELEP----LDRWILSRLHRIIKFATEELERYRFNLIT 644
++ +FA + D DY+ L +++WIL +L K E L++ F T
Sbjct: 794 IYQATKFALMRLGD-DYQPPATEGLSGNESLVEKWILHKLTETSKIVNEALDKRDFLTST 852
Query: 645 RELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEI 704
+ F W+ + D YIE KY + K AK LY LL N + L+ PF+P I+EE+
Sbjct: 853 SSIYEF-WYLICDVYIENSKYLIQEGSAIEKKSAKDTLYILLDNALKLIHPFMPFISEEM 911
Query: 705 YHAMFKDKIGEKSVHLL--SWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNA 762
+ + K + EK+ ++ S+P Y + D K+ +L + E R + + + N
Sbjct: 912 WQRLPK-RSTEKAASIVKASYPVYVSEYDDVKSANAYDLVLNITKEARSLLSEYNILKNG 970
Query: 763 KL 764
K+
Sbjct: 971 KV 972
>emb|CAB60428.1| (AL110500) contains similarity to Pfam domain: PF00133 (tRNA
synthetases class I (I, L, M and V)), Score=910.6,
E-value=1.5e-270, N=1~cDNA EST yk4g12.5 comes from this
gene~cDNA EST yk4g12.3 comes from this gene~cDNA EST
yk49e5.3 comes from this gene~c>
Length = 1050
Score = 319 bits (809), Expect = 8e-86
Identities = 276/979 (28%), Positives = 428/979 (43%), Gaps = 112/979 (11%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYR-LDENKP------SYAIDTPPPFTSGTLHLGHV 54
+P Y P +E W +W +E +K +D+ P S+ + PPP +G LH+GH
Sbjct: 79 IPAAYFPGYVESGWYSWWEKEGFFKPEYIDKLNPGSNPADSFTVCIPPPNVTGNLHVGHA 138
Query: 55 LSHTWIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEK----EFGITKDQ--PEEFLKK 108
L+ T D I R+ RM G LF G D+ G+ T++ VEK E G+T+ + F ++
Sbjct: 139 LATTVEDTITRFNRMHGKRTLFNPGCDHAGIATQVVVEKRLKRERGLTRHDLGRDRFNQE 198
Query: 109 CVEWTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPV 168
W + + + QF ++G S DWD TMD AV ++ + ++ G IYR V
Sbjct: 199 VWHWKNEKGDVIYDQFRKLGASVDWDRAVFTMDPKMCRAVTEAFIRMHESGTIYRSNRLV 258
Query: 169 YWCPKCRTSLAKAEVGYVE----------------EEGYLYYIKLPLADGSGYIPIATTR 212
W R++++ EV E E G L + I ++TTR
Sbjct: 259 NWSCALRSAISDIEVDKKELTGSTLIAVPGYDKKIEFGVLNSFAYKIQGSDEEIVVSTTR 318
Query: 213 PELMPACVAVFVHPDDERYKHLVGKKVKLP-IYEREVPILADEDVDPNFGTGAVYNCTYG 271
E M V VHPDD+RYKHLVGK+ P I R +PI AD V+ FGTGAV
Sbjct: 319 IETMLGDSGVAVHPDDQRYKHLVGKQCIHPFIPTRNLPIFADSFVEMEFGTGAVKITPAH 378
Query: 272 DEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKI 331
D D R NLP I +DG +++ G ++G+K +AR + E L++ GL Y+ ++
Sbjct: 379 DHNDYEVGIRQNLPFHNCITDDGLISQGCGEFSGMKRFDARTAVIEALKEKGL-YRGKED 437
Query: 332 KHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAK--EINWYPEDMFLRLKDWA 389
V+ RS + IE + K QW+++ ++ V ++ PE W
Sbjct: 438 NPMVVPTCSRSKDV--IEPILKPQWYVKCAHMAEKAVAAVANGDLQIIPEFHKATWNRWL 495
Query: 390 ESMDWDWVISRQRVFGTPFPFWVCK--NGHIIPAREEDLPVDPRFDKPPVEKC------P 441
ES DW ISRQ +G P + +G P EE+ V R ++ + K P
Sbjct: 496 ESSR-DWCISRQLWWGHRIPAYYISFADGREQPLPEENYWVSARTEQEALAKAAQKFQVP 554
Query: 442 VCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIR 501
++ DVLD W S + P + W +A K + FP A+ G DI+
Sbjct: 555 EAEILLKWDEDVLDTWFSSGMWPFAVFGWPDATKD-------MDLFFPGAVLETGHDILF 607
Query: 502 TWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEV----------- 550
W +F +LTGK P+K+I+++ M+ GRKMSKS GNV+ P +V
Sbjct: 608 FWVARMVFMAQELTGKLPFKEILLHAMIRDAHGRKMSKSLGNVIDPLDVIRGISLNDLQA 667
Query: 551 --------------------------IPKYGADALRL-WTALAPPGEDHPFKWETVDYNF 583
IP+ G DALR + G D V
Sbjct: 668 QLLGGNLDEKEIAVAKEGQARDYPDGIPECGVDALRFALLSYTSQGRDINLDVLRVHGYR 727
Query: 584 RFLQKVWNIYRFAERHIKDFDYEKYK-DIELE---PLDRWILSRLHRIIKFATEELERYR 639
+F K+W + RFA I D +K +I L+ P D WILSRL + +K E L+ Y
Sbjct: 728 KFCNKLWQVVRFALARISDKPEQKPTFEINLKSATPTDLWILSRLAKAVKETNEALKAYN 787
Query: 640 FNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPH 699
F T F ++ D Y+E +K LYGD+ + A L++ + + L++P +P
Sbjct: 788 FTQATTVTYNFWLYDFCDVYVETIKPVLYGDNTTLRQVAISVLHKCIDTGLRLISPLMPF 847
Query: 700 ITEEIYHAMFK---DKIGEKSVHLLSWP--EYREDRIDEKAEKLGELARKVVSEMRKYKN 754
I+EE++ M + S+ + +P + E +EK E E A++++ ++R +
Sbjct: 848 ISEELWQRMPRLDDSDYTSPSIIVAQYPLTQKYEKYQNEKLEAAFEFAQELIGKVRSLRA 907
Query: 755 SHGMPLNAKLEHVAIYALESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNY 814
+ + + E L I I EK+ I + E +E +
Sbjct: 908 DYDLKKTKITMQILSETPEDESMLNDISAVITTLTFSEKVSILN---KCESDKIEKGSAH 964
Query: 815 KRIGPR---YGKL-----VPRIVEHLKNNAESIAREIKENGKVEFEIDGEK---VELTKE 863
G R Y L VP+ +E L + +K+ G ++ D E+ V++
Sbjct: 965 IACGGRCQVYINLTGIIDVPKEIEKLGAKLQKNQISVKKIGDIQSSADYEQKVPVDIRAL 1024
Query: 864 DVMIKKEVFSEGERVETAV 882
D K + E E + A+
Sbjct: 1025 DQEKKATLEKEIENITAAI 1043
>sp|P41972|SYI_STAAU ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|541337|pir||S40178 isoleucine--tRNA ligase (EC
6.1.1.5) - Staphylococcus aureus
>gi|437916|emb|CAA52296.1| (X74219) isoleucyl-tRNA
synthetase [Staphylococcus aureus]
Length = 917
Score = 318 bits (807), Expect = 1e-85
Identities = 256/925 (27%), Positives = 421/925 (44%), Gaps = 131/925 (14%)
Query: 8 PNEIEPKWQKYWLEEKIYKYRLDENK--PSYAIDTPPPFTSGTLHLGHVLSHTWIDIIAR 65
PN+ EP+ Q+ W E Y L++NK ++ + PP+ +G LH+GH L+ D I R
Sbjct: 21 PNK-EPQIQEKWDAEDQYHKALEKNKGNETFILHDGPPYANGNLHMGHALNKILKDFIVR 79
Query: 66 YKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPE--EFLKKCVEWTWQAIEAMRKQ 123
YK M+G+ + G+D HGLP E + K+ G+ + + EF +KC E+ + IE +K
Sbjct: 80 YKTMQGFYAPYVPGWDTHGLPIEQALTKK-GVDRKKMSTAEFREKCKEFALEQIELQKKD 138
Query: 124 FIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV 183
F R+G D++ Y T+ Y+AA + E KGLIY+ + PVYW P +SLA+AE+
Sbjct: 139 FRRLGVRGDFNDPYITLKPEYEAAQIRIFGEMADKGLIYKGKKPVYWSPSSESSLAEAEI 198
Query: 184 GYVEEEGYLYYIKLPLADGSGYIP------IATTRPELMPACVAVFVHPD---------D 228
Y ++ Y+ + D G + I TT P +P+ VA+ VHP+
Sbjct: 199 EYHDKRSASIYVAFNVKDDKGVVDADAKFIIWTTTPWTIPSNVAITVHPELKYGQYNVNG 258
Query: 229 ERY------------------------KHLVGKKVKL-----PIYEREVPILADEDVDPN 259
E+Y K GK+++ P +RE ++ + V +
Sbjct: 259 EKYIIAEALSDAVAEALDWDKASIKLEKEYTGKELEYVVAQHPFLDRESLVINGDHVTTD 318
Query: 260 FGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDL 319
GTG V+ E D + ++Y LPVI I++ G E G + G+ ++A K + + L
Sbjct: 319 AGTGCVHTAPGHGEDDYIVGQKYELPVISPIDDKGVFTEEGGQFEGMFYDKANKAVTDLL 378
Query: 320 EKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRV----KDFTDEIVKVAKEIN 375
+ G L K + I H H R+ P+ QWF + +D D I ++N
Sbjct: 379 TEKGALLKLDFITHS-YPHDWRTK--KPVIFRATPQWFASISKVRQDILDAIENTNFKVN 435
Query: 376 WYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPARE-----EDLPVDP 430
W ++ ++D E WVISRQRV+G P P + +NG II +E DL +
Sbjct: 436 WGKTRIYNMVRDRGE-----WVISRQRVWGVPLPVFYAENGEIIMTKETVNHVADLFAEH 490
Query: 431 R----FDKPPVEKCP-------VCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEE 479
F++ + P TD++D W DS + +G E
Sbjct: 491 GSNIWFEREAKDLLPEGFTHPGSPNGTFTKETDIMDVWFDSG----------SSHRGVLE 540
Query: 480 AKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSK 539
+ E +FP + +G+D R W +I + G P+K ++ +G V +G+KMSK
Sbjct: 541 TRP--ELSFPADMYLEGSDQYRGWFNSSITTSVATRGVSPYKFLLSHGFVMDGEGKKMSK 598
Query: 540 SYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERH 599
S GNV+ PD+V+ + GAD RLW + D E + +K+ N RF +
Sbjct: 599 SLGNVIVPDQVVKQKGADIARLWVSSTDYLADVRISDEILKQTSDVYRKIRNTLRFMLGN 658
Query: 600 IKDF--DYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVAD 657
I DF D + + EL +DR++L+RL E + + I +E+ FI E+++
Sbjct: 659 INDFNPDTDSIPESELLEVDRYLLNRLREFTASTINNYENFDYLNIYQEVQNFINVELSN 718
Query: 658 DYIEMVKYRLYGDDEESKLK--AKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGE 715
Y++ K LY + +S ++ + LY++L ++ LLAP + H EE++ + E
Sbjct: 719 FYLDYGKDILYIEQRDSHIRRSMQTVLYQILVDMTKLLAPILVHTAEEVW--SHTPHVKE 776
Query: 716 KSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESY 775
+SVHL P K+ E+ + ++ + R + N L ALE+
Sbjct: 777 ESVHLADMP------------KVVEVDQALLDKWRTFMN---------LRDDVNRALETA 815
Query: 776 DDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKNN 835
+ K+I K + + I + F E ++ + + ++V+ L +
Sbjct: 816 RNEKVIGKSLEAKVTIASNDKFNAS--------EFLTSFDALHQLFIVSQVKVVDKLDDQ 867
Query: 836 AESIAREIKENGKVEFE-IDGEKVE 859
A + E+G + E DGEK E
Sbjct: 868 ATAY-----EHGDIVIEHADGEKCE 887
>pdb|1FFY|A Chain A, Insights Into Editing From An Ile-Trna Synthetase
Structure With Trna(Ile) And Mupirocin
>gi|6137708|pdb|1QU2|A Chain A, Insights Into Editing
From An Ile-Trna Synthetase Structure With Trna(Ile) And
Mupirocin >gi|6137710|pdb|1QU3|A Chain A, Insights Into
Editing From An Ile-Trna Synthetase Structure With
Trna(Ile) And Mupirocin
Length = 917
Score = 317 bits (803), Expect = 4e-85
Identities = 256/925 (27%), Positives = 421/925 (44%), Gaps = 131/925 (14%)
Query: 8 PNEIEPKWQKYWLEEKIYKYRLDENK--PSYAIDTPPPFTSGTLHLGHVLSHTWIDIIAR 65
PN+ EP+ Q+ W E Y L++NK ++ + PP+ +G LH+GH L+ D I R
Sbjct: 21 PNK-EPQIQEKWDAEDQYHKALEKNKGNETFILHDGPPYANGNLHMGHALNKILKDFIVR 79
Query: 66 YKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPE--EFLKKCVEWTWQAIEAMRKQ 123
YK M+G+ + G+D HGLP E + K+ G+ + + EF +KC E+ + IE +K
Sbjct: 80 YKTMQGFYAPYVPGWDTHGLPIEQALTKK-GVDRKKMSTAEFREKCKEFALEQIELQKKD 138
Query: 124 FIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV 183
F R+G D++ Y T+ Y+AA + E KGLIY+ + PVYW P +SLA+AE+
Sbjct: 139 FRRLGVRGDFNDPYITLKPEYEAAQIRIFGEMADKGLIYKGKKPVYWSPSSESSLAEAEI 198
Query: 184 GYVEEEGYLYYIKLPLADGSGYIP------IATTRPELMPACVAVFVHPD---------D 228
Y ++ Y+ + D G + I TT P +P+ VA+ VHP+
Sbjct: 199 EYHDKRSASIYVAFNVKDDKGVVDADAKFIIWTTTPWTIPSNVAITVHPELKYGQYNVNG 258
Query: 229 ERY------------------------KHLVGKKVKL-----PIYEREVPILADEDVDPN 259
E+Y K GK+++ P +RE ++ + V +
Sbjct: 259 EKYIIAEALSDAVAEALDWDKASIKLEKEYTGKELEWVVAQHPFLDRESLVINGDHVTTD 318
Query: 260 FGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDL 319
GTG V+ E D + ++Y LPVI I++ G E G + G+ ++A K + + L
Sbjct: 319 AGTGCVHTAPGHGEDDYIVGQQYELPVISPIDDKGVFTEEGGQFEGMFYDKANKAVTDLL 378
Query: 320 EKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRV----KDFTDEIVKVAKEIN 375
+ G L K + I H H R+ P+ QWF + +D D I ++N
Sbjct: 379 TEKGALLKLDFITHS-YPHDWRTK--KPVIFRATPQWFASISKVRQDILDAIENTNFKVN 435
Query: 376 WYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPARE-----EDLPVDP 430
W ++ ++D E WVISRQRV+G P P + +NG II +E DL +
Sbjct: 436 WGKTRIYNMVRDRGE-----WVISRQRVWGVPLPVFYAENGEIIMTKETVNHVADLFAEH 490
Query: 431 R----FDKPPVEKCP-------VCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEE 479
F++ + P TD++D W DS + +G E
Sbjct: 491 GSNIWFEREAKDLLPEGFTHPGSPNGTFTKETDIMDVWFDSG----------SSHRGVLE 540
Query: 480 AKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSK 539
+ E +FP + +G+D R W +I + G P+K ++ +G V +G+KMSK
Sbjct: 541 TRP--ELSFPADMYLEGSDQYRGWFNSSITTSVATRGVSPYKFLLSHGFVMDGEGKKMSK 598
Query: 540 SYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERH 599
S GNV+ PD+V+ + GAD RLW + D E + +K+ N RF +
Sbjct: 599 SLGNVIVPDQVVKQKGADIARLWVSSTDYLADVRISDEILKQTSDDYRKIRNTLRFMLGN 658
Query: 600 IKDF--DYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVAD 657
I DF D + + EL +DR++L+RL E + + I +E+ FI E+++
Sbjct: 659 INDFNPDTDSIPESELLEVDRYLLNRLREFTASTINNYENFDYLNIYQEVQNFINVELSN 718
Query: 658 DYIEMVKYRLYGDDEESKLK--AKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGE 715
Y++ K LY + +S ++ + LY++L ++ LLAP + H EE++ + E
Sbjct: 719 FYLDYGKDILYIEQRDSHIRRSMQTVLYQILVDMTKLLAPILVHTAEEVW--SHTPHVKE 776
Query: 716 KSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESY 775
+SVHL P K+ E+ + ++ + R + N L ALE+
Sbjct: 777 ESVHLADMP------------KVVEVDQALLDKWRTFMN---------LRDDVNRALETA 815
Query: 776 DDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKNN 835
+ K+I K + + I + F E ++ + + ++V+ L +
Sbjct: 816 RNEKVIGKSLEAKVTIASNDKFNAS--------EFLTSFDALHQLFIVSQVKVVDKLDDQ 867
Query: 836 AESIAREIKENGKVEFE-IDGEKVE 859
A + E+G + E DGEK E
Sbjct: 868 ATAY-----EHGDIVIEHADGEKCE 887
>pir||B82843 valyl-tRNA synthetase XF0134 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9104920|gb|AAF82947.1|AE003867_1
(AE003867) valyl-tRNA synthetase [Xylella fastidiosa]
Length = 994
Score = 315 bits (799), Expect = 1e-84
Identities = 248/876 (28%), Positives = 378/876 (42%), Gaps = 142/876 (16%)
Query: 6 YDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIAR 65
YDP E + W E ++ Y I PPP +GTLH+GH T +D + R
Sbjct: 8 YDPTSFEARLYAAW--EAAGHFKPSGTGQPYTILLPPPNVTGTLHMGHAFQQTLMDALVR 65
Query: 66 YKRMRGYNVLFPQGFDNHGLPTELKVEKEF-----GITKDQ--PEEFLKKCVEWTWQAIE 118
Y RM G + L+ G D+ G+ TE+ V + G T+D + F+ K EW Q+ +
Sbjct: 66 YHRMCGDDTLWQVGTDHAGIATEMVVSRNVVLEGHGETRDSLGRDGFINKVWEWKQQSGD 125
Query: 119 AMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSL 178
+ +Q R+G SADW TMD AAV ++ + +Y+ GLIYR + V W P +T++
Sbjct: 126 TIERQMRRLGVSADWSRSTFTMDPQPSAAVTEAFVRWYEAGLIYRGQRLVNWDPVLKTAI 185
Query: 179 AKAEVGYVEEEGYLYYIKLPLADGSGY-------------------IPIATTRPELMPAC 219
+ EV V EEG L+ I+ PL+DG Y + +ATTRPE +
Sbjct: 186 SDLEVENVAEEGMLWSIRYPLSDGVTYEHVEHDAAGNEILRETRDSLIVATTRPETLLGD 245
Query: 220 VAVFVHPDDERYKHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQ 279
AV VHP+D RY L+GK V LP+ R +P++ D VDP FGTG V D D
Sbjct: 246 TAVMVHPEDRRYTALIGKTVTLPLTGRHIPVIGDAYVDPTFGTGVVKVTPAHDFNDYQIG 305
Query: 280 KRYNLPVIIAINE-------------------DGTMNENAGP-----------------Y 303
R+ LP+I +++ T N + P
Sbjct: 306 LRHRLPMIQVLDDAACIVSKTSIQSGMPSGATSDTTNTPSDPEASSAANQHDTLVMPAHL 365
Query: 304 AGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDF 363
AGL ARK+I DL+ GLL +V R + P QWF++++
Sbjct: 366 AGLDRYAARKQILADLDAQGLLVAAIPHTLQVPRGDRTGQVIEP---YLTAQWFVKMETL 422
Query: 364 TDEIVKVAKE--INWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPA 421
+ + + + + P + + W E++ DW ISRQ +G P W G +
Sbjct: 423 AARGLALVERGAVTFVPPNWINTYRHWMENIQ-DWCISRQLWWGHRIPAWFDTQGGVYVG 481
Query: 422 REEDLPVDPRFDKPPVEKCPVCGAEIEPV--TDVLDCWVDSSITPLIITRWHEAIKGDEE 479
R E V G E+ DVL+ W S + P W +
Sbjct: 482 RSE----------AEVRAKHALGPEVTLTQDNDVLETWFSSQLWPFSTLGWPDP---TAM 528
Query: 480 AKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSK 539
A+ + P+++ G DII W I T TG P+ D+ I G++ G+KMSK
Sbjct: 529 AEHGYARYLPSSVLVTGFDIIFFWVARMIMATDHFTGNVPFHDVYITGLIRDAQGQKMSK 588
Query: 540 SYGNVVAPDEVI------------------PK-------------------YGADALRLW 562
S GNV+ P ++I PK +GADALR
Sbjct: 589 SKGNVLDPLDIIDGITLDDLVAKRTTGLMQPKLAEKIAKATRKEFPEGIAPHGADALRFT 648
Query: 563 -TALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKD------FDYEKYKDIELEP 615
ALA G D F + F K+WN RF + D ++ +D + P
Sbjct: 649 IAALATHGRDIKFDLGRAEGYKNFCNKLWNATRFVLMNTADDTAHSPAQHQAGQDGQDAP 708
Query: 616 --------LDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRL 667
++WILSRL I A + YRF+L+ + L F W+E D ++E+ K L
Sbjct: 709 RTPQPRTDAEQWILSRLTAITAEAHAQFAAYRFDLLAQALYEFAWNEFCDWFVELAKPAL 768
Query: 668 YGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYR 727
DD ++ + L +L ++ LL P +P ITEE++ + ++G ++ L+ P +
Sbjct: 769 NSDDTQAAASTRHTLLYVLETLLRLLHPLIPFITEELWRQV-APRLGIQATTLMLRPYPQ 827
Query: 728 EDRIDEKAEKLG----ELARKVVSEMRKYKNSHGMP 759
+++ A E + +VS +R+ +++ +P
Sbjct: 828 PQQLETAAFANAAADVEWLKIMVSALRRIRSTLNVP 863
>sp|P75304|SYV_MYCPN VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|2146697|pir||S73687 valine--tRNA ligase (EC 6.1.1.9)
valS - Mycoplasma pneumoniae (strain ATCC 29342)
>gi|1674039|gb|AAB96009.1| (AE000034) valyl-tRNA
synthetase [Mycoplasma pneumoniae]
Length = 838
Score = 314 bits (797), Expect = 2e-84
Identities = 227/773 (29%), Positives = 355/773 (45%), Gaps = 65/773 (8%)
Query: 5 KYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIA 64
+YD + W +K + +NK + PPP +GTLH+GH + D I
Sbjct: 10 QYDFKTVSTGLYDSWSSASFFKPQ--KNKVPFTAILPPPNLTGTLHIGHAFEVSITDQIM 67
Query: 65 RYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEF-------LKKCVEWTWQAI 117
R+KR+RGY V + GFD+ G+ T+ K EK T PE F +K ++W
Sbjct: 68 RFKRLRGYGVNWIPGFDHAGIATQTKYEKLARETN--PEYFQAPRKQKVKMIMDWALTQG 125
Query: 118 EAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTS 177
+ ++ Q +G S +W+ T+ V S ++ +++G IY+ E V W K T+
Sbjct: 126 DTIQSQIKSLGASLNWNQVNFTLSKKASQIVNDSFIQLFEQGFIYQAETLVNWDTKLNTA 185
Query: 178 LAKAEVGYVEEEGYLYYIKLPLADG-SGYIPIATTRPELMPACVAVFVHPDDERYKHLVG 236
++ EV + LYYI LA+ + +ATTRPE + V +FVHP D+ Y V
Sbjct: 186 ISNIEVINKPVDQQLYYIAYKLANNPKKRLVVATTRPETIFVDVCLFVHPKDKHYHSFVK 245
Query: 237 KKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTM 296
+KV P+ +P+ D VD FGTG + D D ++Y LP + I+ +G +
Sbjct: 246 QKVVNPLTGALMPVFTDSYVDKKFGTGVLKCTPAHDFNDFALNEKYRLPFVSCIDHNGLL 305
Query: 297 NENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQW 356
NE+A + GL V AR+++ E L+ LL K + V +ERS + +E L KQW
Sbjct: 306 NEHAKQFTGLTVSAARQQVVEFLQTQKLLVKTMPLTSNV-GFSERSDTV--VEPLLSKQW 362
Query: 357 FIRVKDFTDEIVKVAKEINWYPEDMFLRLKD----WAESMDWDWVISRQRVFGTPFPFWV 412
F+ + +K A I YPE + R W + W ISRQ ++G P P W
Sbjct: 363 FVDLPK-----LKKALAIKKYPELIPKRFNKQVTRWLSQLK-PWCISRQLIWGHPIPVWT 416
Query: 413 CKNGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHE 472
K + P TDVLD W SS+ PLI WH+
Sbjct: 417 HKQSGALHVG---------------STAPTDKQNYTQSTDVLDTWFSSSLWPLICLDWHK 461
Query: 473 AIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGP 532
+H PT L G DI+ W F ++ T + P+K ++I+G+V
Sbjct: 462 N-----------KHFVPTDLLVTGYDILFFWVLRMTFNSYFQTKQLPFKQVLIHGLVRDA 510
Query: 533 DGRKMSKSYGNVVAPDEVIPKYGADALRLW-TALAPPGEDHPFKWETVDYNFRFLQKVWN 591
RKMSKS N + P ++I YGADA RL+ T+ PG+D F + + FL K+WN
Sbjct: 511 QNRKMSKSLNNGINPMDLIRDYGADATRLFLTSNHTPGDDLIFNEQKLKSAANFLNKLWN 570
Query: 592 IYRFAERHIKDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFI 651
+ ++ + + + +RWI ++L ++I T+ L++Y+ L + L+ FI
Sbjct: 571 VTKYVLQLGEQAKTVPSTHLPSTLSERWIWAKLKQLIVQTTKLLDKYQLALANQALVNFI 630
Query: 652 WHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKD 711
W++ + +IE +K +D + +L +++L+ P + E IY
Sbjct: 631 WNDFCNTFIETIKQ----EDTALLPQLYTTAKTVLSTAVVMLSTVTPFLAERIY-----Q 681
Query: 712 KIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKL 764
+ SV SWP + K KL + VS +R YK ++ + N L
Sbjct: 682 QFHSGSVMQASWPTAKA----VKPPKLFADVVEAVSSLRHYKANNQLVANQNL 730
>pir||T34946 probable isoleucyl-tRNA synthetase - Streptomyces coelicolor
>gi|5689948|emb|CAB51985.1| (AL109663) putative
isoleucyl-tRNA synthetase [Streptomyces coelicolor
A3(2)]
Length = 1047
Score = 314 bits (795), Expect = 4e-84
Identities = 263/948 (27%), Positives = 423/948 (43%), Gaps = 105/948 (11%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLD--ENKPSYAIDTPPPFTSGTLHLGHVLSHTW 59
+P + D +E +W E+KI+ L+ E +P + PP +G H+ + +
Sbjct: 9 VPAQVDLPALEHAVLDFWREQKIFAKSLEQSEGRPEWVFYEGPPTANGMPGAHHIEARVF 68
Query: 60 IDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCVEWT 113
D+ R++ MRGY+V G+D HGLP EL VEKE G + Q EF KC E
Sbjct: 69 KDVFPRFRTMRGYHVGRKAGWDCHGLPVELAVEKELGFSGKQDIEAYGIAEFNAKCRESV 128
Query: 114 WQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPK 173
+ +A + R+GY AD Y TMD Y +V SL E + KGL+ ++ WCP+
Sbjct: 129 TRHTDAFEELTTRMGYWADLQDPYRTMDPEYIESVWWSLKEIFNKGLLVQDHRVAPWCPR 188
Query: 174 CRTSLAKAEV--GYVEEEGYLYYIKLPLADG----SGYIPIATTRPELMPACVAVFVHPD 227
C T L+ E+ GY Y++ PL G + + TT P + + AV HPD
Sbjct: 189 CGTGLSDHELAQGYETVVDPSVYVRFPLTSGPLAGEAALVVWTTTPWTLVSNTAVAAHPD 248
Query: 228 -------DERYKHLV---------------------GKKVKLPIYER-----EVPILADE 254
D K +V G +++ Y+R E P A
Sbjct: 249 VTYVVATDGEEKLVVAEPLLAKALGEGWETTGQSFTGAEMERWTYQRPFELVEFPEPAHY 308
Query: 255 DVDPNF-----GTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVE 309
V+ ++ GTG V+ E D+ + Y LPV+ + DGT E+ G+ +
Sbjct: 309 VVNADYVTTEDGTGLVHQSPAFGEDDLKVCRAYGLPVVNPVRPDGTFEEDVPLVGGVFFK 368
Query: 310 EARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVK 369
+A +K+ EDLE GLL+K +H H R C + + W+IR D +++
Sbjct: 369 KADEKLTEDLETRGLLFKHIPYEHSY-PHCWR--CHTALLYYAQPSWYIRTTAIKDRLLQ 425
Query: 370 VAKEINWYPEDM-FLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGH--IIPAREE-- 424
++ NW+P+ + R DW + + DW +SR R +GTP P W C H ++ +R E
Sbjct: 426 ENEKTNWFPDAVKHGRYGDWLNN-NIDWALSRNRYWGTPLPIWRCAEDHLTVVGSRAELT 484
Query: 425 ------DLPVDPRFDKPPVEKCPV------CGAEIEPVTDVLDCWVDSSITPLIITRWHE 472
+DP +P ++ C E V +V+D W DS P +W
Sbjct: 485 ELSGTDQSSLDPH--RPFIDDVTFTCAQEGCSLEAVRVPEVIDAWYDSGSMPF--AQWGY 540
Query: 473 AIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLT-GKKPWKDIVINGMVAG 531
K K+ FE +P + D R W FYT+ L K ++++V G +
Sbjct: 541 PYKN----KELFESRYPAQFISEAIDQTRGW-FYTLMAVGTLVFDKSSYENVVCLGHILA 595
Query: 532 PDGRKMSKSYGNVVAPDEVIPKYGADALRLWTAL-APPGEDHPFKWETVDYNFR-FLQKV 589
DGRKMSK GN++ P ++ ++GADA+R + A P T+ R L
Sbjct: 596 EDGRKMSKHLGNILQPIPLMDQHGADAVRWFMAAGGSPWAARRVGHGTIQEVVRKTLLTY 655
Query: 590 WNIYRFAERHIKDFDYEKYK----DIELEPLDRWILSRLHRIIKFATEELERYRFNLITR 645
WN F + + + + + LDRW+LS LH + T+ L+ Y +
Sbjct: 656 WNTVAFQALYARTTGWAPSEADPAPADRPVLDRWLLSELHALTDQVTQALDAYDTQRAGK 715
Query: 646 ELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIY 705
L F+ ++++ Y+ + R + D+ A L+E++ V L+AP P ITE ++
Sbjct: 716 LLSAFV-DDLSNWYVRRSRRRFWQGDK----AALRTLHEVVETVTKLMAPLTPFITERVW 770
Query: 706 HAMFKDKI--GEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAK 763
+ +SVHL SWPE ID + K L R++V R + G+
Sbjct: 771 QDLVVPVTPGAPESVHLSSWPEADLTAIDPELSKQMVLVRRLVELGRATRAESGVKTRQP 830
Query: 764 LEHVAIYALESYDDLK-LIEKDIAGTMNIEKLEIFKGEPQLEERIVE--VKPNYKRIGPR 820
L A+ A+ +D L + I +N+ L ++ +V+ K N++ +G R
Sbjct: 831 LSR-ALIAVAGFDTLSPELHSQITEELNVASLASLS---EVGGSLVDTTAKANFRALGKR 886
Query: 821 YGKLVPRIVEHL-KNNAESIAREIKENGKVEFEIDGEKVELTKEDVMI 867
+GK V + + + +A +++ ++E G E+DGE V L ++V+I
Sbjct: 887 FGKRVQDVAKAVAAADAAALSLALRE-GTASVEVDGETVTLAPDEVII 933
>sp|P47576|SYV_MYCGE VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|1361896|pir||I64236 valine--tRNA ligase (EC 6.1.1.9)
- Mycoplasma genitalium >gi|3844913|gb|AAC71557.1|
(U39714) valyl-tRNA synthetase (valS) [Mycoplasma
genitalium]
Length = 837
Score = 311 bits (788), Expect = 2e-83
Identities = 226/788 (28%), Positives = 377/788 (47%), Gaps = 66/788 (8%)
Query: 4 KKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDII 63
K YD N + + W +K + D+N AI PPP +GTLH+GH + D I
Sbjct: 9 KNYDFNLVSDGLYEIWNNAGFFKPK-DKNNSFTAI-LPPPNLTGTLHIGHAFEVSITDQI 66
Query: 64 ARYKRMRGYNVLFPQGFDNHGLPTELKVEK--------EFGITKDQPEEFLKKCVEWTWQ 115
R+K+M+G+++ + GFD+ G+ T+ K EK F D+ E + + W
Sbjct: 67 MRFKKMQGFSINWIPGFDHAGIATQTKYEKIALKENQKYFDADDDKKSEMI---MNWALN 123
Query: 116 AIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCR 175
E ++ Q +G +W T+ + V Y+ G IY+ V W K
Sbjct: 124 QSEIIKNQLKSLGVCLNWSETKFTLSEQANKIVNNCFKNLYENGFIYQAYTLVNWDTKLN 183
Query: 176 TSLAKAEVGYVEEEGYLYYIKLPLA-DGSGYIPIATTRPELMPACVAVFVHPDDERYKHL 234
T+++ EV +L+Y+ LA D + +ATTRPE + A V + V+P D+RY +
Sbjct: 184 TAISNIEVINKPVNQHLHYVVYKLANDSKQELIVATTRPETIFADVCLLVNPKDKRYTNF 243
Query: 235 VGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDG 294
K V P+ +++P++ D VD FGTG + D D +Y + I+ +G
Sbjct: 244 WNKLVVNPLTGKQIPVVTDSYVDIKFGTGILKCTPAHDFNDYEINTKYKFDFLSCIDSNG 303
Query: 295 TMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKK 354
+N+NA + GL V +AR KI + LEK LL K + V +ERS + +E + K
Sbjct: 304 ILNQNASKFQGLSVLQARNKIVKWLEKNKLLVKSIPLTSNV-GFSERSGTV--VEPMLSK 360
Query: 355 QWFIRVKDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCK 414
QWF+ + D + + K ++ P+ ++ +W + W ISRQ ++G P W
Sbjct: 361 QWFVDLPKLKDHLY-LKKYPDFIPKRFNKQVSNWLNKLK-PWCISRQLIWGHKIPVWFEN 418
Query: 415 NGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAI 474
N I E+ + + DVLD W SS+ PLI W +
Sbjct: 419 NTGEIVVGEKPSKNLQNYTRS---------------KDVLDTWFSSSLWPLICLNWEQDD 463
Query: 475 KGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDG 534
E T L G DI+ W +F +F T K P+K ++I+G+V
Sbjct: 464 SFHE-----------TELLVTGYDILFFWVLRMLFNSFFETKKLPFKTVLIHGLVRDEQN 512
Query: 535 RKMSKSYGNVVAPDEVIPKYGADALRLW-TALAPPGEDHPFKWETVDYNFRFLQKVWNIY 593
RKMSKS N + P ++I YGADA+RL+ + PG+D F + + + FL K+WN+
Sbjct: 513 RKMSKSLNNGIDPVDLIRNYGADAVRLFLCSNHTPGDDLIFSEQKIKSAWNFLNKLWNVT 572
Query: 594 RFAERHIKDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWH 653
+F + D + Y +L + WIL++L ++I+ T+ L++++ L + L+ F+W
Sbjct: 573 KFVIQLENDQEI-SYDLDKLSLSETWILAKLDKVIQKITKLLDKFQLALANQILVKFVWD 631
Query: 654 EVADDYIEMVKYRLYGDDEESKLKAKV--ALYELLYNVMLLLAPFVPHITEEIYHAMFKD 711
+ + +IE +K E ++LK ++ +L N+ +LL+ VP ++E IY
Sbjct: 632 DFCNTFIEAIK------KEPNQLKPQLFYTAKSVLSNIAILLSITVPFLSERIY-----Q 680
Query: 712 KIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYA 771
+ KSV +WP + +I KL +L ++++R Y+ + LN++ + V I +
Sbjct: 681 QFNNKSVMQATWPLATKIKI----PKLFDLVLAAINDLRNYRKQY--MLNSQQKLVVILS 734
Query: 772 LESYDDLK 779
++ D+K
Sbjct: 735 GKNAVDVK 742
>sp|P28350|SYV_NEUCR VALYL-TRNA SYNTHETASE, MITOCHONDRIAL PRECURSOR (VALINE--TRNA
LIGASE) (VALRS) >gi|101878|pir||A41251 valine--tRNA
ligase (EC 6.1.1.9) - Neurospora crassa
Length = 1093
Score = 310 bits (785), Expect = 6e-83
Identities = 230/794 (28%), Positives = 364/794 (44%), Gaps = 84/794 (10%)
Query: 6 YDPNEIEPKWQKYWLEEKIYKYRLDENKPS---YAIDTPPPFTSGTLHLGHVLSHTWIDI 62
Y+P+ +E W ++W + +K KPS + I PPP +G LH GH L+++ D
Sbjct: 140 YNPSAVEAAWYQWWEKAGYFKPE-SCRKPSAGKFVIPLPPPNVTGALHCGHALANSLQDT 198
Query: 63 IARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQ------PEEFLKKCVEWTWQA 116
+ R+ RM+GY L+ G D+ G+ T+ VEK + + E+F EW +
Sbjct: 199 LIRWYRMKGYETLWVPGCDHAGISTQSVVEKMLWKKEKKIRQELGREKFTDLVWEWKGEY 258
Query: 117 IEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRT 176
+ + +G S DW E TMD AA ++ + +GLIYR V WC T
Sbjct: 259 HQRINNAQKLMGGSMDWSREAFTMDKNLTAATMETFCRLHDEGLIYRSNRLVNWCTHLNT 318
Query: 177 SLAKAEV--------------GYVE--EEGYLYYIKLPLADGSGYIPIATTRPELMPACV 220
+L+ EV GY + E G L + K + I +ATTRPE M
Sbjct: 319 ALSGLEVETKEITGRTLLDVPGYDKKVEFGVLTHFKYQIDGSEETIEVATTRPETMLGDT 378
Query: 221 AVFVHPDDERYKHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQK 280
+ V+P+D RY HLVGK + P +R +PI+ D VD FGTGAV D D +
Sbjct: 379 GIAVNPEDPRYTHLVGKFARHPFVDRLLPIVTDNYVDKEFGTGAVKLTPAHDFNDYQLGQ 438
Query: 281 RYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTE 340
R+NL I +NE+GT+N+NAGP+ G K +AR + E+L K+GL KKE ++ E
Sbjct: 439 RHNLEFINILNENGTLNDNAGPFKGQKRFDARYTVVEELTKLGLFVKKEPNPMKI-PLCE 497
Query: 341 RSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKE--INWYPEDMFLRLKDWAESMDWDWVI 398
+S + IE + +QW++R+K+ + ++V +E + PE K W + DW I
Sbjct: 498 KSKDV--IEPMMTEQWWVRMKEMGEAALQVVEEGKVKISPESATKSYKRWLADIQ-DWCI 554
Query: 399 SRQRVFGTPFP----FWVCKNGHIIPAREEDLPVDPRFDKPPVEKCPVCGAE--IEPVTD 452
SRQ +G P + + G + E + + + + G + +E D
Sbjct: 555 SRQLWWGHRIPAYRVIFEGEEGQRENEKSEWVVGRTQEEAQAKAEAKFAGRKFTLEQDPD 614
Query: 453 VLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTF 512
LD W S + P+ I W D F+ FPT++ G DI+ W I +
Sbjct: 615 CLDTWFSSGLWPMAILGWPNTENLD------FKKFFPTSMLETGWDILFFWVSRMIMLSL 668
Query: 513 KLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEV---------------------- 550
K+TG+ P+ ++ + ++ +GRKMSKS GNV+ P ++
Sbjct: 669 KMTGEVPFTEVYCHSLIRDSEGRKMSKSLGNVIDPLDIIRGIELEDLHAKLLVGNLKEEE 728
Query: 551 ---------------IPKYGADALRL-WTALAPPGEDHPFKWETVDYNFRFLQKVWNIYR 594
IP+ GADA+R + G D F + RF K+W +
Sbjct: 729 VARATKYQKTAFPGGIPECGADAMRFTLLSYTTGGGDINFDIRVMHAYRRFCNKIWQASK 788
Query: 595 FAERHI-KDFDYEKYKD-IELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIW 652
+ + +DF + D ++WIL R++ +K E LE F+ T+ F +
Sbjct: 789 YVLGKLPQDFMPKGELDTANFSVPEKWILHRMNVAVKGMNEALEAREFSRATKVAYQFFY 848
Query: 653 HEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDK 712
E+ D +IE K L E + + LY L + LL P +P+ITEE++ + + +
Sbjct: 849 DELCDVFIENSKGILSDGTPEEQQSVQQTLYHALDVALRLLHPIMPYITEELWQRLPRKQ 908
Query: 713 IGEKSVHLLSWPEY 726
+++ L +P +
Sbjct: 909 GDGETIMLAPYPAF 922
>sp|P56690|SYI_THETH ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|4930049|pdb|1ILE| Isoleucyl-Trna Synthetase
Length = 821
Score = 309 bits (784), Expect = 7e-83
Identities = 245/830 (29%), Positives = 371/830 (44%), Gaps = 93/830 (11%)
Query: 7 DPN--EIEPKWQKYWLEEKIYKYRLDENK--PSYAIDTPPPFTSGTLHLGHVLSHTWIDI 62
+PN ++E + +W EKI++ ++ K P Y + PP +G H+GH + ++ D+
Sbjct: 7 EPNFPKLEEEVLAFWKREKIFQKSVENRKGGPRYTVYEGPPTANGLPHVGHAQARSYKDL 66
Query: 63 IARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCVEWTWQA 116
RYK MRGY G+D HGLP EL+VEK+ G+ + E F + C E +
Sbjct: 67 FPRYKTMRGYYAPRRAGWDTHGLPVELEVEKKLGLKSKREIEAYGIERFNQACRESVFTY 126
Query: 117 IEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRT 176
+ RI Y D + Y T++ Y ++ SL + +GL+YR+ V +CP+C T
Sbjct: 127 EKEWEAFTERIAYWVDLEDAYATLEPTYIESIWWSLKNLFDRGLLYRDHKVVPYCPRCGT 186
Query: 177 SLAKAEV--GYVEEEGYLYYIKLPLADGS------GYIPIATTRPELMPACVAVFVHPD- 227
L+ EV GY E + Y++ PL + + I TT P +P VA VHP+
Sbjct: 187 PLSSHEVALGYKEIQDPSVYVRFPLKEPKKLGLEKASLLIWTTTPWTLPGNVAAAVHPEY 246
Query: 228 --------DERY------------------KHLVGKKVKLPIYEREVP---------ILA 252
DE K GK ++ Y P +LA
Sbjct: 247 TYAAFQVGDEALILEEGLGRKLLGEGTQVLKTFPGKALEGLPYTPPYPQALEKGYFVVLA 306
Query: 253 DEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEAR 312
D V GTG V+ +D+ + Y LP++ ++E+G + P+ GL EA
Sbjct: 307 DY-VSQEDGTGIVHQAPAFGAEDLETARVYGLPLLKTVDEEGKLLVE--PFKGLYFREAN 363
Query: 313 KKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAK 372
+ I DL GLL+K+E H H R C P+ + WFI+ F DE+++ +
Sbjct: 364 RAILRDLRGRGLLFKEESYLHSY-PHCWR--CSTPLMYYATESWFIKNTLFKDELIRNNQ 420
Query: 373 EINWYPEDMFL-RLKDWAESMDWDWVISRQRVFGTPFPFWVC---------------KNG 416
EI+W P + R +W +++ DW +SR R +GTP P WVC K
Sbjct: 421 EIHWVPPHIKEGRYGEWLKNLV-DWALSRNRYWGTPLPIWVCQACGKEEAIGSFQELKAR 479
Query: 417 HIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKG 476
P E P P D+ VE CG + V V+D W DS P +
Sbjct: 480 ATKPLPEPFDPHRPYVDQ--VELACACGGTMRRVPYVIDVWYDSGAMPFASLHY------ 531
Query: 477 DEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRK 536
E ++ F +FP +G D R W L G +K+++ +G++ G+K
Sbjct: 532 PFEHEEVFRESFPADFIAEGIDQTRGWFNSLHQLGVMLFGSIAFKNVICHGLILDEKGQK 591
Query: 537 MSKSYGNVVAPDEVIPKYGADALRLWTAL-APPGEDHPFKWETVDYNFR-FLQKVWNIYR 594
MSKS GNVV P ++I K+GADALR + + APP D F V R + +WN+Y
Sbjct: 592 MSKSKGNVVDPWDIIRKFGADALRWYIYVSAPPEADRRFGPNLVRETVRDYFLTLWNVYS 651
Query: 595 F--AERHIKDFDYEKYKDIELEP-LDRWILSRLHRIIKFATEELERYRFNLITRELMTFI 651
F ++ D + E P +DRW+L+R+ +I+ TE LE Y R L F+
Sbjct: 652 FFVTYANLDRPDLKNPPPPEKRPEMDRWLLARMQDLIQRVTEALEAYDPTTSARALRDFV 711
Query: 652 WHEVADDYIEMVKYRLY-GDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFK 710
+++ Y+ + R + +D + A LYE L V L APF P + E ++ + +
Sbjct: 712 VEDLSQWYVRRNRRRFWKNEDALDREAAYATLYEALVLVATLAAPFTPFLAEVLWQNLVR 771
Query: 711 D--KIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGM 758
++SVHL WPE DE KVV R + G+
Sbjct: 772 SVRLEAKESVHLADWPEADPALADEALVAQMRAVLKVVDLARAARAKSGV 821
>gb|AAF58412.1| (AE003819) CG4062 gene product [Drosophila melanogaster]
Length = 1049
Score = 307 bits (779), Expect = 3e-82
Identities = 252/854 (29%), Positives = 375/854 (43%), Gaps = 111/854 (12%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIY-----KYRLDENKPS--YAIDTPPPFTSGTLHLGHV 54
LP Y P +E +W +W +E + + +D P+ + + PPP +G+LHLGH
Sbjct: 90 LPDAYSPRYVEAQWYSWWEKEGFFTPEYGRASIDAPNPNGKFVMIIPPPNVTGSLHLGHA 149
Query: 55 LSHTWIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP--------EEFL 106
L++ D I RY RM+G L+ G D+ G+ T++ VEK + +D+ E+F+
Sbjct: 150 LTNAIEDAITRYHRMKGRTTLWVPGCDHAGIATQVVVEKL--LWRDEKLSRHDLGREKFI 207
Query: 107 KKCVEWTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEH 166
++ +W + + +Q +G S DW TMD AV ++ + +++G IYR
Sbjct: 208 ERIWDWRREKGGRIYEQLKSLGSSYDWTRVAFTMDPKLCRAVTEAFVRLHEEGSIYRSSR 267
Query: 167 PVYWCPKCRTSLAKAEVGYVE----------------EEGYLYYIKLPLADGSGYIPIAT 210
V W R++++ EV VE E G L + I +AT
Sbjct: 268 LVNWSCTLRSAISDIEVDKVEIPGRTFLSIPGYEDKVEFGVLIKFAYKVEGSDEEIIVAT 327
Query: 211 TRPELMPACVAVFVHPDDERYKHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTY 270
TR E M AV VHP D+RYKHL GK V P R +PI+ DE VD FGTGAV
Sbjct: 328 TRIETMLGDTAVAVHPQDDRYKHLHGKFVVHPFSTRRLPIVCDEFVDMAFGTGAVKITPA 387
Query: 271 GDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEK 330
D D KR NLP I N+DG + + G + G+K E RKKI E L+ + LY++
Sbjct: 388 HDPNDYEVGKRCNLPFITIFNDDGYIIGDYGEFTGMKRFECRKKILEKLKALN-LYRETL 446
Query: 331 IKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAK--EINWYPEDMFLRLKDW 388
V+ RS + +E L K QW++ D + + E+ PE K W
Sbjct: 447 NNPMVVPICSRSKDV--VEPLIKPQWYVSCSDMAASATEAVRSGELKIIPEH---HTKTW 501
Query: 389 AESMDW--DWVISRQRVFGTPFPFWVCK-------------NGHIIPAREEDLPVDPRFD 433
MD DW +SRQ +G P + + I AR E + +
Sbjct: 502 YHWMDGIRDWCVSRQLWWGHRIPAYHVSFTDPSLQTGSNDDEQYWIVARSEAEALTKAAE 561
Query: 434 KPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALR 493
+ V+ + + E DVLD W S I P + W + K + +PT+L
Sbjct: 562 RFGVDASKIVLKQDE---DVLDTWFSSGIFPFSVFGWPDQTKD-------LQTFYPTSLL 611
Query: 494 PQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEV--- 550
G DI+ W +F KL GK P+K++ ++ MV GRKMSKS GNV+ P +V
Sbjct: 612 ETGHDILFFWVARMVFFGQKLLGKLPFKEVYLHPMVRDAHGRKMSKSLGNVIDPMDVIRG 671
Query: 551 ----------------------------------IPKYGADALR--LWTALAPPGEDHPF 574
IP+ G+DALR L + + +
Sbjct: 672 ITLEGLHAQLVGSNLDPREIEKAKAGQKQDYPQGIPECGSDALRFALCAYITQARDINLD 731
Query: 575 KWETVDYNFRFLQKVWNIYRFAERHI---KDFDYEKYKDIELEPLDRWILSRLHRIIKFA 631
+ Y F F K+WN +FA + + FD E + +D WILSRL I+
Sbjct: 732 INRVLGYRF-FCNKLWNATKFALLYFTGSEKFDTELSASAAINQMDAWILSRLAAAIEAC 790
Query: 632 TEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVML 691
E Y F T F +++ D Y+E +K EE + A+ LY L +
Sbjct: 791 NTGFESYDFAAATSACYAFWLYDLCDVYLECLKPIFQSGSEEQQTAARRTLYVCLDYGLR 850
Query: 692 LLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRK 751
LL+PF+P ITEE+Y + + S+ + S+P R K E E +K +R
Sbjct: 851 LLSPFMPFITEELYQRLPRAN-PAPSICVASYPSNTSWR-STKIESDVEFVQKAARIIRS 908
Query: 752 YKNSHGMPLNAKLE 765
++ + +P K E
Sbjct: 909 ARSDYNLPNKVKTE 922
>sp|P41368|SYIP_STAAU ISOLEUCYL-TRNA SYNTHETASE, MUPIROCIN RESISTANT (ISOLEUCINE--TRNA
LIGASE) (ILERS) (MUPIROCIN RESISTANCE PROTEIN)
>gi|581558|emb|CAA53189.1| (X75439) isoleucyl tRNA
synthetase [Staphylococcus aureus]
Length = 1024
Score = 307 bits (777), Expect = 5e-82
Identities = 269/942 (28%), Positives = 425/942 (44%), Gaps = 103/942 (10%)
Query: 2 LPKKY--DPNEIEPKWQKYWLEEKIYKYRLDENK--PSYAIDTPPPFTSGTLHLGHVLSH 57
+ KKY NEI +W +KI+K +D K S+ PP +G H GHVL
Sbjct: 1 MTKKYLNTQNEISA----FWNTQKIFKKSIDNRKGQESFVFYDGPPTANGLPHAGHVLGR 56
Query: 58 TWIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCVE 111
D++AR K M+G+ V G+D HGLP EL+VEK+ GI Q E F+ +C +
Sbjct: 57 VIKDLVARLKTMQGFYVERKAGWDTHGLPVELEVEKKIGIKGKQDIEKYGIENFINECKK 116
Query: 112 WTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWC 171
+ + R +GY D D Y T+++ Y +V L F+KKGL+Y+ +C
Sbjct: 117 SVFNYEKEWRDFSKDLGYWVDMDSPYITLENNYIESVWNILSTFHKKGLLYKGHKVTPYC 176
Query: 172 PKCRTSLAKAEV--GYVEEEGYLYYIKLPLADGSG-YIPIATTRPELMPACVAVFVHPD- 227
+T+L+ EV GY + +K L + Y TT P +PA VA+ ++ D
Sbjct: 177 THDQTALSSHEVAQGYKNVKDLSAVVKFQLTNSKDTYFLSWTTTPWTLPANVALAINKDL 236
Query: 228 -----------------------DERYK--------HLVGKKVKLPIYEREVPILADEDV 256
E+Y+ +L+ K +P +E + + A V
Sbjct: 237 NYSKIRVENEYYILATDLINSIITEKYEIIDTFSGSNLINLKY-IPPFESDGLVNAYYVV 295
Query: 257 DPNF-----GTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEA 311
D F GTG V+ E D +L + I +G N+ G K + +
Sbjct: 296 DGEFVTNSEGTGIVHIAPAHGEDDYQLVLERDLDFLNVITREGVYNDRFPELVGNKAKNS 355
Query: 312 RKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVA 371
+I + L K LLYKK+K +H H R C P+ + WFI+ +F +EI+
Sbjct: 356 DIEIIKLLSKKQLLYKKQKYEHNY-PHCWR--CGNPLIYYAMEGWFIKTTNFKNEIINNN 412
Query: 372 KEINWYPEDMFL-RLKDWAESMDWDWVISRQRVFGTPFPFWVCK--NGHIIPAREEDLP- 427
I W+P + R+ ++ E+M DW I R R +GTP W+C N P+ +DL
Sbjct: 413 NNIEWFPSHIKEGRMGNFLENMV-DWNIGRNRYWGTPLNVWICNDCNHEYAPSSIKDLQN 471
Query: 428 -------VDPRFDKPPVEK----CPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKG 476
D +P V+ CP C ++ V +V+D W DS P + H
Sbjct: 472 NSINKIDEDIELHRPYVDNITLSCPKCNGKMSRVEEVIDVWFDSGSMPF--AQHHYPF-- 527
Query: 477 DEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRK 536
+ +K F +FP +G D R W + + + L GK +K + G + +G+K
Sbjct: 528 --DNQKIFNQHFPADFIAEGVDQTRGWFYSLLVISTILKGKSSYKRALSLGHILDSNGKK 585
Query: 537 MSKSYGNVVAPDEVIPKYGADALRLWTAL--APPGEDHPFKWETV-DYNFRFLQKVWNIY 593
MSKS GNV+ P E+I KYGAD+LR W + + P + F V +F+ + NIY
Sbjct: 586 MSKSKGNVINPTELINKYGADSLR-WALISDSAPWNNKRFSENIVAQTKSKFIDTLDNIY 644
Query: 594 RFAERHIKDFDYEKYKDI--ELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFI 651
+F + K Y +I LD W LSRL+ +IK + + Y F R L+
Sbjct: 645 KFYNMYNKIDHYNPNNEITKSRNTLDNWALSRLNTLIKESNIYVNNYDFTSAAR-LINEY 703
Query: 652 WHEVADDYIEMVKYRLYGDD-EESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFK 710
+ +++ YI + R + K A LYE+L + L+APFVP I+E+I++
Sbjct: 704 TNTISNWYIGDSRGRFWEQGISNDKKDAYNTLYEILTTLSRLVAPFVPFISEKIHY---- 759
Query: 711 DKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIY 770
+ KSVHL +P+Y+E I++ E K+V R+ + + + + L + I
Sbjct: 760 -NLTGKSVHLQDYPQYKESFINQALEDEMHTVIKIVELSRQARKNADLKIKQPLSKMVIK 818
Query: 771 ALESYDDLKLIE---KDIAGTMNIEKLEIFKGEPQLEERIV-EVKPNYKRIGPRYGKLVP 826
S +L + I +NI+ +E+ + + I E+K N+ +GP+ G
Sbjct: 819 P-NSQLNLSFLPNYYSIIKDELNIKNIEL---TDNINDYITYELKLNFSSVGPKLGNKTK 874
Query: 827 RIVEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVMIK 868
I + + +E + + E+ F+ ELTK+D +IK
Sbjct: 875 NIQTLIDSLSEYDKKSLIESN--NFKSLSSDAELTKDDFIIK 914
>pir||T51503 valine--tRNA ligase-like protein - Arabidopsis thaliana
>gi|9755723|emb|CAC01835.1| (AL391147) valine--tRNA
ligase-like protein [Arabidopsis thaliana]
Length = 1093
Score = 306 bits (776), Expect = 6e-82
Identities = 255/894 (28%), Positives = 404/894 (44%), Gaps = 145/894 (16%)
Query: 12 EPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRMRG 71
E K K+W + +K D+ + I PPP +G+LH+GH + T DI+ RY RM G
Sbjct: 287 EEKIYKWWESQGYFKPNFDQGGSPFVIPMPPPNVTGSLHMGHAMFVTLEDIMVRYNRMNG 346
Query: 72 YNVLFPQGFDNHGLPTELKVEKEF---GITKDQ--PEEFLKKCVEWTWQAIEAMRKQFIR 126
L+ G D+ G+ T+L VEK GI + +EF K+ EW + + Q R
Sbjct: 347 RPTLWLPGTDHAGIATQLVVEKMLASEGIKRVDLGRDEFTKRVWEWKEKYGGTITNQIKR 406
Query: 127 IGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVGYV 186
+G S DW E T+D+ AV ++ ++ + KGLIY+ + V W P +T+++ EV Y
Sbjct: 407 LGASCDWSRERFTLDEQLSRAVVEAFVKLHDKGLIYQGSYMVNWSPNLQTAVSDLEVEYS 466
Query: 187 EEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVGKKVKLPI-YE 245
EE G+LY+IK +A ++ IATTRPE + VA+ VHP+D+RY VG+ +P+ Y
Sbjct: 467 EEPGFLYHIKYRVAGSPDFLTIATTRPETLFGDVALAVHPEDDRYSKYVGQTAIVPMTYG 526
Query: 246 REVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAG 305
R VPI+AD+ VD +FGTG + D D + ++ LP++ +N+D T+N+ AG
Sbjct: 527 RHVPIIADKYVDKDFGTGVLKISPGHDHNDYLLARKLGLPILNVMNKDATLND----VAG 582
Query: 306 LKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTD 365
L E R+K+ DLE++GL KKE RV R + P L KQWF+ + +
Sbjct: 583 LFWFEVREKLWADLEEIGLAVKKEPHTLRVPRSQRGGEVIEP---LVSKQWFVHMDPLAE 639
Query: 366 EIVKVA--KEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPARE 423
+ + KE+ PE KD C+ +I+ A+
Sbjct: 640 KALLAVENKELTIIPERF---EKD-------------------------CEEDYIV-AKS 670
Query: 424 EDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKW 483
+ ++ +K + EI DVLD W SS+ P W + A K
Sbjct: 671 AEEALEKALEKYGKD------VEIYQDPDVLDTWFSSSLWPFSTLGWPDV------AAKD 718
Query: 484 FEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGN 543
F + +PT + G + + TG P+ + ++G++ GRKMSKS GN
Sbjct: 719 FNNFYPTNMLETG----------MVMMGIEFTGTVPFSHVYLHGLIRDSQGRKMSKSLGN 768
Query: 544 VVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRF-------- 595
V+ P + I +G DALR AL G+D E + N F K+WN +F
Sbjct: 769 VIDPLDTIKDFGTDALRFTIALGTAGQDLNLSTERLTANKAFTNKLWNAGKFVLHSLPSL 828
Query: 596 ----AERHIKDFDYEKYKDIELEPL-DRWILSRLHRIIKFATEELERYRFNLITRELMTF 650
A ++ D +K + + PL + W +S+LH +I T E+
Sbjct: 829 SDTSAWENLLDLKLDKEETLLSLPLPECWAVSKLHILIDSVTASYEKL------------ 876
Query: 651 IWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFK 710
+GD V LY + N++ LL PF+P +TE+++ A+
Sbjct: 877 ----------------FFGD--------AVLLY-VFENILKLLHPFMPFVTEDLWQAL-- 909
Query: 711 DKIGEKSVHLLSWPEYREDRIDE---KAEKLGELARKVVSEMRKY-----KNSHGMPLNA 762
++++ + WP+ R E + E L L R + + +Y K + +
Sbjct: 910 -PYRKEALIVSPWPQNSLPRNVESIKRFENLQALTRAIRNARAEYSVEPVKRISASVVGS 968
Query: 763 KLEHVAIYALESYDDLKLIEKDIA--GTMNI-------EKLEIFKGEPQLEERIVEVKPN 813
+ + AL S DL + A G N+ E LE + + + EV+
Sbjct: 969 AEKEKEVLALLSRLDLNNVHFSNAPPGDANLSVHLVASEGLEAYLPLAAMVDISSEVQRI 1028
Query: 814 YKRIG---PRYGKLVPRI--VEHLKNNAESIAREIKENGKVEFEIDGEKVELTK 862
KR+ Y L+ R+ + ++ E + R +KE + E EK++LTK
Sbjct: 1029 SKRLSKMQTEYDALITRLSSPKFVEKAPEEVVRGVKE----QVEELEEKIKLTK 1078
>sp|O66651|SYI_AQUAE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437546|pir||G70327 isoleucine--tRNA ligase (EC
6.1.1.5) - Aquifex aeolicus >gi|2983002|gb|AAC06614.1|
(AE000683) isoleucyl-tRNA synthetase [Aquifex aeolicus]
Length = 956
Score = 301 bits (762), Expect = 3e-80
Identities = 262/918 (28%), Positives = 406/918 (43%), Gaps = 136/918 (14%)
Query: 3 PKKYDPNEIEPKWQKYW--LEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWI 60
P K + + EP+ + W L EKI K R + + + + PP+ +G +H+GH L+
Sbjct: 20 PMKANLPQREPQILEKWKGLYEKIQKER--KGREVFVLHDGPPYANGHIHVGHALNKILK 77
Query: 61 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPE-----EFLKKCVEWTWQ 115
D+I +Y + G NV F G+D HGLP E VEKE K + E EF + C E+ +
Sbjct: 78 DVINKYNLLIGKNVNFIPGWDCHGLPIERAVEKELSKKKIKKESLPKTEFRELCREYAKK 137
Query: 116 AIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCR 175
+ R+ F+R+G DW+ Y TMD Y+A + L +F+++GL YR + PVYWC +
Sbjct: 138 YVNIQREDFVRLGVLGDWEHPYLTMDPKYEAQEIRELGKFFERGLAYRSKKPVYWCIYDK 197
Query: 176 TSLAKAEVGYVEEEGYLYYIKLPLADGSGY--------IPIATTRPELMPACVAVFVHPD 227
T+ A+AEV Y E+E Y+K PL G + I TT P +PA + + V D
Sbjct: 198 TAEAEAEVEYYEKEDPSIYVKFPLKSGEKFGIKDKKVFAIIWTTTPWTLPANLGIMVKED 257
Query: 228 DE------------------------------------RYKHLVGKKVKLPIYEREV--- 248
+ + K LVG + P E+E
Sbjct: 258 ADYVLVEVEDEVWIVAKELMDKFFETVNRPEGLVLETVKGKDLVGLEYTHPFVEKEKLKG 317
Query: 249 -----------PILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMN 297
I E V + GTG V+ ++D V +RY L ++++G
Sbjct: 318 HLSEETLKNMWKIYPSEFVSLDTGTGLVHMAPGHGQEDYVVGQRYGLEPYAPVSDEGRFV 377
Query: 298 ENAGPYA-GLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQW 356
E A + ++V +A I L++ G L +EKI+H H R C P+ QW
Sbjct: 378 EPAPEFLINVRVFDANHLIVGVLKEKGFLVHEEKIRHSY-PHCWR--CKNPVIFRATPQW 434
Query: 357 FIRV------KDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPF 410
FI + K ++ +++ W PE R+K E+ DW ISRQR +G P
Sbjct: 435 FIGMDIEFFGKTLRQRALEEIEKVKWIPEYGKNRIKSMVENRP-DWCISRQRFWGVPITV 493
Query: 411 WVCKN-GHIIPARE-----------EDLPVDPRFDK------PPVEKCPVCGAE-IEPVT 451
+ C+N G II RE + D F+ P KCP CG +
Sbjct: 494 FYCENCGEIIKDREVFERVAQLVENSEKGSDVWFELTSSQLLPEGYKCPKCGGDSFTKEE 553
Query: 452 DVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRT 511
D+LD W DS + + R K D L +G+D R W ++ +
Sbjct: 554 DILDVWFDSGCSHAAVIRPLGFQKAD--------------LYLEGSDQHRGWFQASLLES 599
Query: 512 FKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGED 571
+ P+K ++ +G + GRKMSKS GNV++P EV+ ++GAD LRLW ED
Sbjct: 600 VGSYLEAPYKAVLTHGFIVDEKGRKMSKSLGNVISPQEVVKEFGADILRLWVVSEDYTED 659
Query: 572 HPFKWETVDYNFRFLQKVWNIYRFAERHIKDFD-------YEKYKDIELEPLDRWILSRL 624
+ +K+ N RF ++ DF+ +EK L DRWI+S L
Sbjct: 660 VKLGKNLLKKIADDYRKIRNTLRFIIGNLYDFNPRTNALPFEK-----LHHFDRWIISEL 714
Query: 625 HRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRL--YGDDEESKLKAKVAL 682
++K E E++ F + + F+ ++ Y++++K RL Y + A+ AL
Sbjct: 715 QNLLKKVHENYEKFLFYRVHNHIKNFVITTLSAIYLDVLKDRLYVYAPASWERRSAQTAL 774
Query: 683 YELLYNVMLLLAPFVPHITEEIYHAMFK-DKIGEKSVHLLSWPEYREDRIDEKAEKLGEL 741
+ LL + AP++ EE++ + K D +SV L P+ E+ DE+ K E+
Sbjct: 775 WHLLIALTTSTAPYLSFTAEELWEHVGKLDPSLPESVFLYEMPKPDENLKDEEVLKDYEI 834
Query: 742 ARKVVSEM-------RKYKNSHGMPLNAKLEHVAIYALESYDDLKLIEKDIAGTMNIEKL 794
KV E+ RK K P AK+ ++ES LK E + + ++
Sbjct: 835 LLKVRDEVMRALEVARKEKGIIKHPYEAKVYIRGDESVESL--LKKYEDYLNFFFTVSQV 892
Query: 795 EIFK-GEPQLEERIVEVK 811
E+ + GE Q+E + VK
Sbjct: 893 ELREGGEVQIEGEELPVK 910
>sp|O13651|SYIC_SCHPO ISOLEUCYL-TRNA SYNTHETASE, CYTOPLASMIC (ISOLEUCINE--TRNA LIGASE)
(ILERS) >gi|7492116|pir||T40751 isoleucyl-trna
synthetase, cytoplasmic - fission yeast
(Schizosaccharomyces pombe) >gi|2257546|dbj|BAA21439.1|
(AB004538) ISOLEUCYL-TRNA SYNTHETASE ,CYTOPLASMIC
[Schizosaccharomyces pombe] >gi|2950493|emb|CAA17821.1|
(AL022072) isoleucyl-trna synthetase, cytoplasmic
[Schizosaccharomyces pombe]
Length = 1064
Score = 300 bits (759), Expect = 6e-80
Identities = 257/962 (26%), Positives = 439/962 (44%), Gaps = 116/962 (12%)
Query: 12 EPKWQKYWLEEKIY--KYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRM 69
E K ++W E + + +L + +P+Y PPF +G H GH+L+ T D + RY +
Sbjct: 9 EEKIVEFWREIDAFHTQLKLSQGRPTYTFFDGPPFATGRPHHGHLLASTIKDSVTRYACL 68
Query: 70 RGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCVEWTWQAIEAMRKQ 123
+GY+V G+D HGLP E +++K+ GIT +++ +C + R
Sbjct: 69 KGYHVERRFGWDTHGLPVEHEIDKKLGITGSDDVMAMGIDKYNAECRKIVMTYASEWRAT 128
Query: 124 FIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLA--KA 181
R+G D+D +Y T+ + +V E + KG +YR + + C T L+ +A
Sbjct: 129 VERLGRWIDFDNDYKTLYPSFMESVWWVFKELHTKGKVYRGYRVMPYSTACTTPLSNFEA 188
Query: 182 EVGYVEEEGYLYYIKLP-LADGSGYIPIATTRPELMPACVAVFVHPD-----------DE 229
+ Y E + ++D TT P +P+ +A+ VHPD ++
Sbjct: 189 QQNYKEVPDPAIVVAFQSISDPEVSFLAWTTTPWTLPSNLALAVHPDLQYIKILDKDSNK 248
Query: 230 RY---------------------------KHLVGKKVKLPIY--------EREVPILADE 254
+Y K L G+K + P++ ER + + +
Sbjct: 249 KYILMESCLGILYKNPKKANFEILERFQGKALDGQKYE-PLFPYFKSTFGERAFKLYSAD 307
Query: 255 DVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIA-------INEDGTMNENAGPYAGLK 307
V+ GTG V+ E D + + +I A ++E G + +AG
Sbjct: 308 YVEEGSGTGIVHQAPAFGEAD--YDAAWAAGIIDADHQPPCPVDEQGLLTSEITDFAGQY 365
Query: 308 VEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEI 367
V++A K+I L+ G L K +I H RS +P WF+RVK+ T+E+
Sbjct: 366 VKDADKEIIRSLKASGHLVKHSQIFHSY-PFCWRSDTPLIYRAVPS--WFVRVKEITNEM 422
Query: 368 VKVAKEINWYPEDMF-LRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGH------IIP 420
V+ +W P+++ R +W ++ DW ISR R +GTP P WV + I
Sbjct: 423 VENVMSTHWVPQNIRDKRFANWLKNAR-DWNISRNRYWGTPIPLWVSDDYEEVVCIGSIK 481
Query: 421 AREEDLPVDPRFD--KPPVEKCPVCGAE----IEPVTDVLDCWVDSSITPLIITRWHEAI 474
EE V D + ++ + + + V++V DCW +S P H
Sbjct: 482 ELEELSGVSNITDIHRDSIDHITIPSKKGKGTLHRVSEVFDCWFESGSMPYASR--HYPF 539
Query: 475 KGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDG 534
+ EE F+H FP +G D R W + L K P+K+++++G+V DG
Sbjct: 540 ERIEE----FKHGFPADFISEGVDQTRGWFYTLTVLGTLLFDKAPYKNVIVSGLVMAEDG 595
Query: 535 RKMSKSYGNVVAPDEVIPKYGADALRLWTALAP--PGEDHPFKWETV-DYNFRFLQKVWN 591
+KMSK N P+ +I KYG+DALRL+ +P E FK + V + R L WN
Sbjct: 596 KKMSKRLKNYPEPNLIIEKYGSDALRLYLINSPVVRAEILKFKEDGVREVVTRVLIPWWN 655
Query: 592 IYRFAERHI--------KDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLI 643
Y+F E KDF ++ + +DRWIL+R +I F EE+++YR +
Sbjct: 656 SYKFFEAQAALYKKVTGKDFVFDDAATLSSNVMDRWILARCQSLIGFVDEEMKQYRLYTV 715
Query: 644 TRELMTFIWHEVADDYIEMVKYRLYGDDEE-SKLKAKVALYELLYNVMLLLAPFVPHITE 702
+L+ I E+ + YI + RL G+D E + A L+E+L+ ++ ++ PF P ITE
Sbjct: 716 VPQLLGLI-EEMTNWYIRFNRRRLKGEDGEIETINALNVLFEVLFTLVRIMGPFTPFITE 774
Query: 703 EIYH------AMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSH 756
IY + K++I +SVH L +P Y+ + DE + + + ++ R + +
Sbjct: 775 NIYQHLRNYMPIDKNEISLRSVHFLPFPTYKSELDDETVLRRVKRMQTIIELARYVREQN 834
Query: 757 GMPLNAKLEH-VAIYALESY-DDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNY 814
+ L L+ + I E Y +D KL+E+ IA +N+ ++ +F + + V+ ++
Sbjct: 835 NISLKTPLKTLIVILTNEEYLEDAKLLERYIAEELNVREV-VFTSNEEKYGVVYSVQADW 893
Query: 815 KRIGPRYGKLVPRIVEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVMIKKEVFSE 874
+G + K + R+ + L N +E ++N K+ +DG +EL + D+ I + V +
Sbjct: 894 PVLGKKLRKDMARVKKALPNVTSEEVKEFQKNKKM--VLDG--IELVEGDLQIIRSVEVK 949
Query: 875 GE 876
E
Sbjct: 950 NE 951
>sp|P57447|SYV_BUCAI VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|10039036|dbj|BAB13070.1| (AP001119) valyl-tRNA
synthetase [Buchnera sp. APS]
Length = 955
Score = 299 bits (757), Expect = 1e-79
Identities = 257/954 (26%), Positives = 423/954 (43%), Gaps = 127/954 (13%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+ K Y+P IE +W + +K E K ++ I PPP +G+LH+GH T +D
Sbjct: 1 MEKIYNPKHIEESLYFFWEKNGFFKPNHLE-KSTFCIMMPPPNITGSLHMGHAFQQTIMD 59
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP-------EEFLKKCVEWTW 114
I+ RY RM+G N + G D+ G+ T++ VE++ K+Q ++F+KK EW
Sbjct: 60 ILIRYHRMQGKNTFWQVGTDHAGIATQILVERQI-FEKEQKTKKDYSRDDFIKKIWEWKK 118
Query: 115 QAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKC 174
Q+ + KQ R+G S DWD E T+D +V+++ + YK LIY+++ V+W K
Sbjct: 119 QSSNIITKQMRRLGISVDWDYEKFTLDPDISNSVREAFIILYKNNLIYQKKKLVHWDSKL 178
Query: 175 RTSLAKAEVGYVEEEGYLYYIKLPLADGS-------GYIPIATTRPELMPACVAVFVHPD 227
T ++ EV + +G ++I+ P+ + Y+ ++TTRPE + A+ V+P+
Sbjct: 179 ETVISDLEVEHRLIKGKKWFIRYPIIENDMSLRSKVKYLIVSTTRPETLLGDTAIAVNPE 238
Query: 228 DERYKHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVI 287
D +Y +G V P+ R +PI+ D D GTG V D D + LP+I
Sbjct: 239 DYKYNQFIGNHVSCPLTNRIIPIIKDRYADLEKGTGCVKITPAHDFNDYKVGLHHKLPMI 298
Query: 288 IAINEDGTMNENAGPY------------------AGLKVEEARKKIAEDLEKMGLLYKKE 329
DG + A Y L + AR +I +++ K+G L K E
Sbjct: 299 NIFTFDGRIKSTAEVYNYKGEKSNQYSTCIPMQFQHLDILSARIEIIKEITKLGFLEKIE 358
Query: 330 KIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVA------KEINWYPEDMFL 383
+ V ++ERS + IE + QW+++ T + KVA K+I + P+
Sbjct: 359 ECNVTV-PYSERSGVI--IEPMLTNQWYLK----TSTLAKVALNAVKDKKIKFIPQQYES 411
Query: 384 RLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHI-IPAREEDLPVDPRFDKPPVEKCPV 442
W +++ DW ISRQ +G P W +I I E+++ + +
Sbjct: 412 MYSSWMNNIE-DWCISRQLWWGHRIPVWYDDQKNIYIGQNEKEIRQAYSISENVL----- 465
Query: 443 CGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRT 502
++ DVLD W S + W + G + + + PT + G DII
Sbjct: 466 ----LKQENDVLDTWFSSGL-------WTFSSLGWPKKTTFLKTFHPTNVLVSGFDIIFF 514
Query: 503 WAFYTIFRTFKLTGKK------PWKDIVINGMVAGPDGRKMSKSYGNVVAP--------- 547
W I T K P+K+I I G++ G+KMSKS GNV+ P
Sbjct: 515 WIARMIMLTMYFMKDKHNNPEVPFKNIYITGLIRDEFGKKMSKSKGNVIDPLDMIDGISL 574
Query: 548 ----------------------------DEVIPKYGADALRL-WTALAPPGEDHPFKWET 578
E I G DALR ++ALA D +
Sbjct: 575 SELIKKRTNNLLQPNLSDKIIQRTIKQFPEGIKSTGTDALRFTFSALASSTRDIQWDMNR 634
Query: 579 VDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIELEPL--DRWILSRLHRIIKFATEELE 636
+ F K+WN RF + +D ++ K+ D++ + L ++WIL + +K E L+
Sbjct: 635 LKGYRNFCNKLWNASRFVLINTQDHNFSKF-DVKRKMLLINKWILIEFNNTVKLYRESLD 693
Query: 637 RYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPF 696
YRF++ L FIW+ D Y+E VK + + K L +L ++ L P
Sbjct: 694 TYRFDIAANILYDFIWNIFCDWYLEFVKIVIKLGSSKEVYCTKNVLVYVLELLLKLAHPI 753
Query: 697 VPHITEEIYHAM-FKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNS 755
+P ITE I+ + I EK++ L +PEY D+K +K++ +R + +
Sbjct: 754 MPFITETIWQRIKLIQNISEKTIMLQDFPEYNHKLFDKKILVQMNWMKKIIVFLRNIRTN 813
Query: 756 HGMPLNAKLEHVAIYALESYDDLKLIEKDIAGTMNI---EKLEIFKGEPQLEERIVEVKP 812
+ + KL + +Y + S + K+I+++I+ NI +K+ I + + I E+
Sbjct: 814 MNVS-STKLLPLFLYNINSEQE-KVIKENISLIKNISFLDKITILSEKYDKDLCIKEIID 871
Query: 813 NYKRIGPRYGKLVPRIVEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVM 866
+ I P KLV VE + R +KE K E I K ++ +D +
Sbjct: 872 GAEIIIPIL-KLVDTKVE--------LKRLVKEQKKTELNIFKIKTKILNKDFL 916
>pir||B81982 probable isoleucine--tRNA ligase (EC 6.1.1.5) NMA0622 [imported] -
Neisseria meningitidis (group A strain Z2491)
>gi|7379357|emb|CAB83912.1| (AL162753) putative
isoleucyl-tRNA synthetase [Neisseria meningitidis Z2491]
Length = 929
Score = 297 bits (752), Expect = 4e-79
Identities = 250/840 (29%), Positives = 385/840 (45%), Gaps = 121/840 (14%)
Query: 12 EPKWQKYWLEEKIYKY--RLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRM 69
EP W K W E+K Y+ + + +P + + PP+ +G +H+GH ++ DII R K
Sbjct: 25 EPAWLKSWYEQKRYQKLREIAKGRPKFILHDGPPYANGDIHIGHAVNKILKDIIIRSKTQ 84
Query: 70 RGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPE-EFLKKCVEWTWQAIEAMRKQFIRIG 128
G++ + G+D HGLP E+ VEK G KD P+ F + C E+ + I +K FIR+G
Sbjct: 85 AGFDAPYVPGWDCHGLPIEVMVEKLHG--KDMPKARFRELCREYAAEQIARQKKDFIRLG 142
Query: 129 YSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVGYVE- 187
DWD Y TMD +A + L E YK G +YR PV +C C +SLA+AEV Y +
Sbjct: 143 VLGDWDNPYLTMDFKTEADTVRMLGEIYKSGYLYRGAKPVQFCLDCGSSLAEAEVEYKDK 202
Query: 188 -----EEGYLYYIKLPLA--------DGSGYIPIATTRPELMPACVAVFVHPDD------ 228
+ GY + LA +G + I TT P +PA AV D
Sbjct: 203 VSPAIDVGYPFKDTAALATAFGLAGIEGKAFAVIWTTTPWTLPASQAVSAGADVVYQLID 262
Query: 229 -----------------ERY---------KHLVGKKVKL-----PIYEREVPILADEDVD 257
+RY G K++ P ER++P+L E V
Sbjct: 263 TPTGKLVLAKDLAEDALKRYGFSDGIAILAETTGDKLENLHMNHPFLERDIPMLNGEHVT 322
Query: 258 PNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAE 317
+ GTG V+ +D +Y + + +N +G AG++V EA I +
Sbjct: 323 TDAGTGLVHTAPAHGLEDYAVCNKYGIELYNPVNAEGKYIGETPRVAGMRVWEANSVILQ 382
Query: 318 DLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRV-------KDFTDEIVKV 370
LE+ G L KI+H H R P+ QWF+ + K D+ +K
Sbjct: 383 WLEETGNLLASSKIEHSYA-HCWRHK--TPLIYRATGQWFVGMDKAGADGKTLRDKAIKA 439
Query: 371 AKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKN-GHIIPAREEDLP-V 428
+ ++P RL+ E DWV+SRQR +GTP F+V K G + P E L V
Sbjct: 440 VDDTEFFPSWGRARLEAMIEGRP-DWVVSRQRYWGTPMTFFVHKETGELHPNSAELLEKV 498
Query: 429 DPRFDKPPVE------KCPVCGAE----IEPVTDVLDCWVDSSITPLIITRWHEAIKGDE 478
R ++ +E K + AE + ++D +D W DS T H ++
Sbjct: 499 AQRIEEKGIEAWFSLDKGELLSAEDCEHYDKLSDTMDVWFDSGST-------HYSVLKQR 551
Query: 479 EAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTG------KKPWKDIVINGMVAGP 532
E W P L +G+D R W F++ LTG + P+K ++ +G V
Sbjct: 552 EELDW-----PADLYLEGSDQHRGW-----FQSSMLTGCASSMGRAPYKQLLTHGFVVDQ 601
Query: 533 DGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNI 592
+GRKMSKS GNVVAP EV ++GAD LRLW A + E + +++ N
Sbjct: 602 NGRKMSKSIGNVVAPQEVYNEFGADILRLWAASTDYSGELAISKEILKRVTESYRRIRNT 661
Query: 593 YRFAERHIKDFD--YEKYKDIELEPLDRWILSRLHRI-IKFATEELERYRFNLITRELMT 649
F ++ DF+ + + ++ +DR+ L R+ + A + RY F+ +E+++
Sbjct: 662 LSFLFANLSDFNPIEDAVQQADMVEIDRYALVLARRLQERVAGDFYPRYAFHFAVKEMVS 721
Query: 650 FIWHEVADDYIEMVKYRLYGD--DEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHA 707
F ++ Y++++K RLY D ++ A+ ALY + +++LL+AP + EE +
Sbjct: 722 FCSEDLGAFYLDILKDRLYTTKADSRARRSAQTALYHITRSLVLLIAPILCFTGEEAW-- 779
Query: 708 MFKDKIG---EKSVHLLSWPEYREDRIDEKAEKLGELARK--VVSEMRKYKNSHGMPLNA 762
D IG E SV +W E+ I+EKAE EL +K + E R+ + PL A
Sbjct: 780 ---DIIGGGAEDSVLFHTWHEF--PTINEKAE--AELVKKWTAIREAREAVTAAIEPLRA 832
>sp|O67411|SYV_AQUAE VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|7437657|pir||A70423 valine--tRNA ligase (EC 6.1.1.9)
- Aquifex aeolicus >gi|2983819|gb|AAC07375.1| (AE000739)
valyl-tRNA synthetase [Aquifex aeolicus]
Length = 1165
Score = 294 bits (745), Expect = 3e-78
Identities = 163/394 (41%), Positives = 235/394 (59%), Gaps = 27/394 (6%)
Query: 4 KKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDII 63
K+Y+P EIE KW +YW+E+ +Y + + +++ PPP +G+LH+GH L+ T D+I
Sbjct: 4 KEYNPREIEEKWSRYWIEKALYHVEKPDKRKKFSVVIPPPNVTGSLHMGHALNATLQDVI 63
Query: 64 ARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP-----EEFLKKCVEWTWQAIE 118
R++RMRG ++ GFD+ G+ T+ VEK+ EEFLKK EW ++
Sbjct: 64 VRWQRMRGRECVWVPGFDHAGIATQYVVEKQLAKEGKSRLELGREEFLKKVWEWVPKSRN 123
Query: 119 AMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSL 178
A+R Q ++G S DW E T+D+ + AV+K+ +++GLIYR E+ V WCP RT+L
Sbjct: 124 AIRTQLTKLGVSVDWKRERFTLDEGFSRAVRKAFRTLFEEGLIYRAEYIVNWCPNDRTAL 183
Query: 179 AKAEVGYVEEEGYLYYIKLPLADGSG-----YIPIATTRPELMPACVAVFVHPDDERYKH 233
+ EV Y EE+G L+YIK P+ D +G +I +ATTRPE M AV V+P+D+RYKH
Sbjct: 184 SDLEVEYEEEKGSLWYIKYPIVDENGKDTGEFITVATTRPETMLGDTAVAVNPNDDRYKH 243
Query: 234 LVGKKVKLPI--YERE----------VPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKR 281
LVGK+ +LP+ +ER+ +PI+ADE V +FGTGAV D D K
Sbjct: 244 LVGKRARLPLVNWERKDLRGNSVSNLIPIIADERVKMDFGTGAVKITPAHDPLDFEIGKT 303
Query: 282 YNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTER 341
++LP + I+E G MNENAG +AG+ EAR+ I L + LL K+E+I H V H R
Sbjct: 304 HDLPFVRVIDETGRMNENAGDFAGMDRYEAREAIVAKLREDELLEKEEEITHSV-GHCYR 362
Query: 342 SSCMAPIELLPKKQWFIRVKD--FTDEIVKVAKE 373
C IE + QWF++V D D +KV +E
Sbjct: 363 --CKTVIEPMVSVQWFVKVSDPRIKDISIKVVEE 394
Score = 172 bits (432), Expect = 1e-41
Identities = 132/462 (28%), Positives = 229/462 (48%), Gaps = 30/462 (6%)
Query: 437 VEKCPVCGAE-IEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQ 495
V +C CG+E +E DVLD W S++ P + W E+ + ++ +PT L
Sbjct: 707 VLRCKKCGSENLEQERDVLDTWFSSALWPFGVFGWPESTED-------LKNLYPTDLLVT 759
Query: 496 GTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYG 555
G DII W I P+ D+ ++ +V GRKMSK+ GNV+ P ++I +YG
Sbjct: 760 GFDIIFFWVARMIMMGTHFMKDIPFYDVYVHALVRDKYGRKMSKTIGNVIDPLDIIERYG 819
Query: 556 ADALRLWTA-LAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHI-KDFDYEKYKDIEL 613
ADALR A L G D E + F K+WN R+ + +DF L
Sbjct: 820 ADALRFTLAILTVQGRDIKLAEEKFEGYKHFANKIWNAARYVLMNTPEDFIARIPYMAPL 879
Query: 614 EPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLY----G 669
+P D+WI+++L+ + + LE Y+++ + F W + D YIE K R+Y
Sbjct: 880 KPEDKWIITKLNETAEEVNKALENYQYSQAAHAIYEFFWSDYCDWYIEFTKERIYKKAPE 939
Query: 670 DDEESKLKAK----VALYELLY---NVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLS 722
D+EE K K + ALY L Y + +L PF+P+ITEE++H + + GE S+ L
Sbjct: 940 DNEEEKAKVENERTTALYTLHYVLEKALRILHPFMPYITEELWHKL-PNAEGE-SISLAE 997
Query: 723 WPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESYDDLKLIE 782
+P+ ED I E+ ++ E ++++S +R ++ + + K++ A + ES ++I+
Sbjct: 998 FPQKNEDEIYEEDKQKVERLKEIISAIRAIRSDLQIKPSEKIK--ASFKTESEFSRRVIQ 1055
Query: 783 KDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLV--PRIVEHLKNNAESIA 840
+ +N+ KLE F+ Q + V I V ++++ + E +
Sbjct: 1056 EFKNHILNLAKLESFEEVSQRPQNTVATFSKDTEIYVHIEGHVDLDKLIQSYEKKREKLL 1115
Query: 841 REIKE-NGKVEFE--IDGEKVELTKEDVMIKKEVFSEGERVE 879
+E++ N K+ E + VE+ +++ IK+E+ ++ ++VE
Sbjct: 1116 KELERVNKKLSNENFLKKAPVEVVEKEKQIKEELENDLKKVE 1157
>sp|Q21926|SYI_CAEEL PROBABLE ISOLEUCYL-TRNA SYNTHETASE, CYTOPLASMIC (ISOLEUCINE--TRNA
LIGASE) (ILERS) >gi|7506619|pir||T24176 hypothetical
protein R11A8.6 - Caenorhabditis elegans
>gi|3879120|emb|CAA94369.1| (Z70310) predicted using
Genefinder~Similarity to Human isoleucyl-tRNA synthetase
(SW:SYI_HUMAN), contains similarity to Pfam domain:
PF00133 (tRNA synthetases class I (I, L, M and V)),
Score=1059.9, E-value=0, N=1~cDNA EST yk26b10.3 comes
from this ge>
Length = 1141
Score = 291 bits (738), Expect = 2e-77
Identities = 255/951 (26%), Positives = 432/951 (44%), Gaps = 121/951 (12%)
Query: 12 EPKWQKYWLEEKIYK--YRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRM 69
E K + W +E ++ L +++P + PPF +G H GH+L+ T D++ R+
Sbjct: 17 EDKVAQKWQDENTFQRSVELSKDRPHFTFYDGPPFATGLPHYGHMLTSTIKDVVGRWAHQ 76
Query: 70 RGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCVEWTWQAIEAMRKQ 123
G+ V G+D HGLP E +++K GI+ Q + +C + + K
Sbjct: 77 NGHYVERRFGWDTHGLPVEYEIDKTLGISGPQDVMKMGIANYNNECRKIVMRYSGEWEKT 136
Query: 124 FIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV 183
R+G D+ +Y T+ W+ +V + E +KKGL+Y+ + + C T L+ E
Sbjct: 137 MGRLGRWVDFKHDYKTLYPWFMESVWWAFSELHKKGLVYKGVKVMPFSTACSTPLSNFEA 196
Query: 184 G--YVEEEGYLYYIKLPLADGSGYIPIA-TTRPELMPACVAVFVHPD------------- 227
G Y + ++ L D +A TT P +P+ +A+ VHPD
Sbjct: 197 GQNYKDVVDPAVFVGFKLLDCPNRQLVAWTTTPWTLPSNLALVVHPDMLYVVTKDKTTGI 256
Query: 228 -----DERY-----------KHLVGKKVKLPIYEREVP-------------ILADEDVDP 258
+ER + L G ++K YE P +L D V
Sbjct: 257 EYVVLEERLGELKNDNLEVIEKLAGSQLKDLRYEPLFPYFAYMREERNAFRVLNDTFVTS 316
Query: 259 NFGTGAVYNCTYGDEQDI-------VWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEA 311
+ GTG V+ Y E D V K + I ++E G Y G+ V++A
Sbjct: 317 DSGTGVVHQAPYFGEIDFQVCVANGVIAKDQKM--ICPVDESGKYTSEVPDYQGVYVKDA 374
Query: 312 RKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVA 371
K I + L++MG L ++ ++KH RS + +P WFI V+ ++
Sbjct: 375 DKLIIKRLKEMGNLVRQAEVKHSY-PFCWRSDTPLLYKAVPS--WFINVETLIPRLLANN 431
Query: 372 KEINWYPEDMFLRLKDWAESMDW-----DWVISRQRVFGTPFPFWVCKNGHIIP-----A 421
E W P F++ K +A +W DW +SR R +GTP WV ++G + A
Sbjct: 432 DETYWVPA--FVKEKRFA---NWLRDARDWAVSRNRFWGTPINLWVSEDGEEVVCVGSIA 486
Query: 422 REEDLPVDPRFD--KPPVEKCPVCGAE----IEPVTDVLDCWVDSSITPLIITRWHEAIK 475
E+L D + V+ + ++ V++V DCW +S P +
Sbjct: 487 ELEELSGQKITDLHRESVDDVTIPSRSGRGVLKRVSEVFDCWFESGSMPYAQNHY----- 541
Query: 476 GDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGR 535
E +K FE NFP +G D R W + + + L K P+K+++ NG+V DG
Sbjct: 542 -PFENRKIFEDNFPADFIAEGIDQTRGWFYTLLVLSTALFNKPPFKNLICNGLVLASDGA 600
Query: 536 KMSKSYGNVVAPDEVIPKYGADALRLWTALAP--PGEDHPFKWETVDYNFRFLQKVW-NI 592
KMSKS N P ++ KYGADALRL+ +P GE+ F+ E V + + W N
Sbjct: 601 KMSKSKKNYPDPMLIVNKYGADALRLYLINSPVVRGENLRFREEGVRDLLKDVFLPWFNA 660
Query: 593 YRFAERHIKDFDYEKYKDIEL-------EPLDRWILSRLHRIIKFATEELERYRFNLITR 645
YRF ++++ +++E ++ +DRWI S + ++ F +E++ YR +
Sbjct: 661 YRFFVQNVQAYEHETGNVFDMNVHVASENVMDRWIESFTNSLVAFVRKEMDSYRLYAVVG 720
Query: 646 ELMTFIWHEVADDYIEMVKYRLYGDDE-ESKLKAKVALYELLYNVMLLLAPFVPHITEEI 704
L F + + + YI + + R+ GD+ + A AL +L ++ L+APF P E I
Sbjct: 721 PLTKF-FDTLTNIYIRLNRKRVKGDNGLHEQHHALAALGRVLILIVRLMAPFTPFFCEYI 779
Query: 705 YHAMFKDKIG--EKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNA 762
+ K IG E+SVH L P+ E IDE E+ E+ R V+ +R ++ G+ +
Sbjct: 780 W-LNLKKVIGSTEESVHFLMLPKPDESLIDETVERRVEVMRNVIDLVRLVRDREGLAVKY 838
Query: 763 KLEHVAIYALES--YDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPR 820
L+ + + +S +D+K +E I +N+ KL + + + Q ++ +PN+K +G R
Sbjct: 839 PLKEMIVINRDSQFLEDVKSLESYILLELNVRKLTVSQ-DKQKYGITLKAEPNFKILGAR 897
Query: 821 YGKLVPRIVEHLKNNAESIAREIKENGKVEFEIDGEKV----ELTKEDVMI 867
++ ++LKN +I E+ +F ++G+ EL+ E+V +
Sbjct: 898 LKGEQKKVADYLKN-------QITESELEKFLLEGKLTVLGHELSSEEVAV 941
>pir||G81036 isoleucyl-tRNA synthetase NMB1833 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7227088|gb|AAF42168.1| (AE002533) isoleucyl-tRNA
synthetase [Neisseria meningitidis MC58]
Length = 929
Score = 290 bits (735), Expect = 4e-77
Identities = 244/840 (29%), Positives = 385/840 (45%), Gaps = 121/840 (14%)
Query: 12 EPKWQKYWLEEKIYKY--RLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRM 69
EP W K W E+K Y+ + + +P + + PP+ +G +H+GH ++ DII R K
Sbjct: 25 EPAWLKSWYEQKRYQKLREIAKGRPKFILHDGPPYANGDIHIGHAVNKILKDIIIRSKTQ 84
Query: 70 RGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPE-EFLKKCVEWTWQAIEAMRKQFIRIG 128
G++ + G+D HGLP E+ VEK G KD P+ F + C E+ + I +K FIR+G
Sbjct: 85 AGFDAPYVPGWDCHGLPIEVMVEKLHG--KDMPKARFRELCREYAAEQIARQKKDFIRLG 142
Query: 129 YSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVGYVE- 187
DWD Y TMD +A + L E YK G +YR PV +C C +SLA+AEV Y +
Sbjct: 143 VLGDWDHPYLTMDFKTEADTVRMLGEIYKSGYLYRGAKPVQFCLDCGSSLAEAEVEYKDK 202
Query: 188 -----EEGYLYYIKLPLA--------DGSGYIPIATTRPELMPACVAVFVHPDD------ 228
+ YL+ LA +G + I TT P +PA AV D
Sbjct: 203 ISPAIDVAYLFKDTAALAAAFGLAGFEGKAFAVIWTTTPWTLPASQAVSAGADVVYQLID 262
Query: 229 -----------------ERY---------KHLVGKKVKL-----PIYEREVPILADEDVD 257
+RY G K++ P ER++P+L E V
Sbjct: 263 TPKGKLVLAKDLAEDALKRYGFSDGIAILAETTGDKLENLHMNHPFLERDIPMLNGEHVT 322
Query: 258 PNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAE 317
+ GTG V+ +D +Y + + +N +G AG++V EA I +
Sbjct: 323 TDAGTGLVHTAPAHGLEDYAVCNKYGIELYNPVNAEGRYIGETPRVAGMRVWEANPVILQ 382
Query: 318 DLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRV-------KDFTDEIVKV 370
LE+ G L KI+H H R P+ QWF+ + K D+ +K
Sbjct: 383 WLEETGNLLASSKIEHSYA-HCWRHK--TPLIYRATGQWFVGMDKAGADGKTLRDKAIKA 439
Query: 371 AKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKN-GHIIPAREEDLP-V 428
+ ++P RL+ E DWV+SRQR +GTP F+V K G + P E L V
Sbjct: 440 VDDTEFFPSWGRARLEAMIEGRP-DWVVSRQRYWGTPMTFFVHKETGELHPNSAELLEKV 498
Query: 429 DPRFDKPPVE------KCPVCGAE----IEPVTDVLDCWVDSSITPLIITRWHEAIKGDE 478
+ ++ +E K + AE + ++D +D W DS T H ++
Sbjct: 499 ALKIEEKGIEAWFSLDKSELLSAEDCENYDKLSDTMDVWFDSGST-------HYSVVKQR 551
Query: 479 EAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTG------KKPWKDIVINGMVAGP 532
E +W P L +G+D R W F++ LTG + P+K ++ +G V
Sbjct: 552 EELEW-----PADLYLEGSDQHRGW-----FQSSMLTGCASSMGRAPYKQLLTHGFVVDG 601
Query: 533 DGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNI 592
+G+KMSKS GNVVAP EV ++GAD LRLW A + E + +++ N
Sbjct: 602 EGKKMSKSIGNVVAPQEVYNEFGADILRLWAASTDYSGELAISKEILKRVTESYRRIRNT 661
Query: 593 YRFAERHIKDFD--YEKYKDIELEPLDRWILSRLHRIIK-FATEELERYRFNLITRELMT 649
F ++ DF+ + + ++ +DR+ + ++ + A + RY F+ +++++
Sbjct: 662 LSFLFANLSDFNPIEDAVQQADMVEIDRYAVVLARQLQECLAGDYYPRYAFHFAVKDIVS 721
Query: 650 FIWHEVADDYIEMVKYRLYGD--DEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHA 707
F ++ Y++++K RLY D ++ A+ ALY + +++LL+AP + EE +
Sbjct: 722 FCSEDLGAFYLDILKDRLYTTKADSHARRSAQTALYHITRSLVLLIAPILCFTGEEAW-- 779
Query: 708 MFKDKIG---EKSVHLLSWPEYREDRIDEKAEKLGELARK--VVSEMRKYKNSHGMPLNA 762
D IG E SV +W E+ I+EK E EL +K + E R+ + PL A
Sbjct: 780 ---DIIGGGEEDSVLFHTWHEF--PTINEKTE--AELVKKWTAIREAREAVTAAIEPLRA 832
>pir||F81719 isoleucyl-tRNA synthetase TC0288 [imported] - Chlamydia muridarum
(strain Nigg) >gi|7190330|gb|AAF39156.1| (AE002296)
isoleucyl-tRNA synthetase [Chlamydia muridarum]
Length = 1036
Score = 289 bits (732), Expect = 9e-77
Identities = 235/928 (25%), Positives = 412/928 (44%), Gaps = 83/928 (8%)
Query: 12 EPKWQKYWLEEKIYKYRLD--ENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRM 69
E K +W E+ I++ L+ + P+++ PPF +G H GH+L+ T D++ RY M
Sbjct: 13 EEKVLTFWKEQNIFQKTLENRDGSPTFSFYDGPPFATGLPHYGHLLAGTIKDVVCRYATM 72
Query: 70 RGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEE------FLKKCVEWTWQAIEAMRKQ 123
G+ V G+D HG+P E +VEK G+T+ + F ++C + ++ ++ +
Sbjct: 73 DGHYVPRRFGWDCHGVPVEYEVEKSLGLTEPGAIDRFGIANFNEECRKIVFRYVDEWKYF 132
Query: 124 FIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV 183
RIG D+ + TMD + +V YK+GL+Y V + K T L+ E
Sbjct: 133 VDRIGRWVDFSATWKTMDLSFMESVWWVFHSLYKQGLVYEGTKVVPFSTKLGTPLSNFEA 192
Query: 184 G--YVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHP--------------- 226
G Y E + K L D G + TT P + + +A+ VHP
Sbjct: 193 GQNYKEVDDPSVVAKFALQDDQGILLAWTTTPWTLVSNMALAVHPGLTYVRIQDKESGEE 252
Query: 227 -------------DDERYK--------HLVGKKV--KLPIYEREVP-----ILADEDVDP 258
D E YK LVG++ P ++ + ++ + ++
Sbjct: 253 YILGQESLARWFPDRESYKWIGQLSGESLVGRRYCPLFPYFQDQQDRGAFRVIPADFIEE 312
Query: 259 NFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAED 318
+ GTG V+ E D + +N+P++ ++ G + G ++ A K IA
Sbjct: 313 SEGTGVVHMAPAFGEADFFACQEHNVPLVCPVDNQGCFTSEVTDFVGEYIKFADKGIARR 372
Query: 319 LEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYP 378
L+ L+ + I+HR S P+ WF+ V+ +++K + I+W P
Sbjct: 373 LKNENKLFYQGTIRHRYPFCWRTDS---PLIYKAVNSWFVSVEKVKHKMLKANESIHWTP 429
Query: 379 EDM-FLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPARE----EDLPVDPRFD 433
+ R W E DW ISR R +GTP P W ++G ++ R E+L D
Sbjct: 430 GHIKHGRFGKWLEGAR-DWAISRNRYWGTPIPIWRSEDGELLVIRSIQELEELSGQKIVD 488
Query: 434 --KPPVEKCPVC--GAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFP 489
+ +++ + G + V DCW DS P + H + EE E FP
Sbjct: 489 LHRHFIDEIVIHKNGKSFHRIPYVFDCWFDSGAMPY--AQNHYPFERAEET----EARFP 542
Query: 490 TALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDE 549
+G D R W + L + +K++++NG+V DG KMSK N +P +
Sbjct: 543 ADFIAEGLDQTRGWFYTLTVIAAALFDQPAFKNVIVNGIVLAEDGNKMSKRLNNYPSPKK 602
Query: 550 VIPKYGADALRLW--TALAPPGEDHPFKWETVDYNFR-FLQKVWNIYRFAERH--IKDFD 604
++ YGADALRL+ ++ ED F + V+ + L + N F + + + F
Sbjct: 603 IMDTYGADALRLYLLNSVVVKAEDLRFSDKGVEAVLKQVLLPLSNALAFYKTYAELYGFS 662
Query: 605 YEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVK 664
+ D+EL +DRWILS L+ ++ E + +Y + + FI ++ + YI +
Sbjct: 663 PNETTDLELAEIDRWILSSLYSLVGKTRENMAQYDLHAAVSPFIDFI-EDLTNWYIRRSR 721
Query: 665 YRLY-GDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSW 723
R + +D + A LYE+L ++APF+P E++Y + + + +SVHL +
Sbjct: 722 RRFWESEDSPDRRAAFATLYEVLMVFSKIIAPFIPFTAEDMYQQL-RVETDPESVHLCDF 780
Query: 724 PEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIY-ALESYDDLKLIE 782
P ++I EK + R++V+ + H + + L+H+ I A E L ++
Sbjct: 781 PHVVLEKILPDLEKKMQDIREIVALGHSLRKEHKLKVRQPLQHMYIVGAKERMAALAQVD 840
Query: 783 KDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKNNAESIARE 842
I +N++++ P+ + VKPN++ +G R G +P I + L ++ +
Sbjct: 841 SLIGEELNVKEVHFCSETPEYVTTL--VKPNFRSLGKRVGNRLPEIQKALAGLSQEQIQA 898
Query: 843 IKENGKVEFEIDGEKVELTKEDVMIKKE 870
NG + + E + L +ED+ + E
Sbjct: 899 FMHNGFMVLSLGEETISLNEEDITVSWE 926
>sp|O84022|SYI_CHLTR ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437566|pir||F71565 probable isoleucine--tRNA ligase
(EC 6.1.1.5) - Chlamydia trachomatis (serotype D, strain
UW3/Cx) >gi|3328409|gb|AAC67609.1| (AE001277)
Isoleucyl-tRNA Synthetase [Chlamydia trachomatis]
Length = 1036
Score = 286 bits (723), Expect = 1e-75
Identities = 234/925 (25%), Positives = 401/925 (43%), Gaps = 83/925 (8%)
Query: 12 EPKWQKYWLEEKIYKYRLD--ENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRM 69
E K +W E+ I++ LD E P+++ PPF +G H GH+L+ T D++ RY M
Sbjct: 13 EEKILSFWKEQDIFQKTLDNREGCPTFSFYDGPPFATGLPHYGHLLAGTIKDVVCRYASM 72
Query: 70 RGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEE------FLKKCVEWTWQAIEAMRKQ 123
G+ V G+D HG+P E +VEK G+T+ E F ++C + ++ + +
Sbjct: 73 DGHYVPRRFGWDCHGVPVEYEVEKSLGLTEPGAIERFGVANFNEECRKIVFRYADEWKYF 132
Query: 124 FIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV 183
RIG D+ + TMD + +V Y +GL+Y V + K T L+ E
Sbjct: 133 VDRIGRWVDFSATWRTMDLSFMESVWWVFRSLYDQGLVYEGTKVVPFSTKLGTPLSNFEA 192
Query: 184 G--YVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHP--------------- 226
G Y E + +K L D G++ TT P + + +A+ VHP
Sbjct: 193 GQNYKEVDDPSVVVKFALQDNQGFLLAWTTTPWTLVSNMALAVHPELTYVRIKDKESGDE 252
Query: 227 -------------DDERYK---HLVGKKVKLPIYEREVPILADED------------VDP 258
D E Y+ L GK + YE P D+ ++
Sbjct: 253 YILGQESLPRWFPDRESYEWIGQLSGKSLVGQSYEPLFPYFQDKKELEAFRILPADFIEE 312
Query: 259 NFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAED 318
+ GTG V+ E D + +N+P++ ++ G + G ++ A K IA
Sbjct: 313 SEGTGIVHMAPAFGEADFFACQEHNVPLVCPVDNQGCYTAEVKDFVGEYIKSADKGIARR 372
Query: 319 LEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYP 378
L+ L+ + ++HR S P+ WF+ V+ +++K + I+W P
Sbjct: 373 LKNENKLFYQGTVRHRYPFCWRTDS---PLIYKAVNSWFVAVEKVKSKMLKANESIHWTP 429
Query: 379 EDMFL-RLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHII--------PAREEDLPVD 429
E + R W E DW ISR R +GTP P W +G ++ A VD
Sbjct: 430 EHIKQGRFGKWLEGAR-DWAISRNRYWGTPIPIWRSDDGELLVIGSIQELEALSGQKIVD 488
Query: 430 PRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFP 489
+ G + V DCW DS P + H + EE E FP
Sbjct: 489 LHRHFIDEIEINQNGKSFRRIPYVFDCWFDSGAMPY--AQNHYPFERAEET----EACFP 542
Query: 490 TALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDE 549
+G D R W + L + +K++++NG++ DG KMSK N +P
Sbjct: 543 ADFIAEGLDQTRGWFYTLTVIAAALFDQPAFKNVIVNGIILAEDGNKMSKRLNNYPSPKM 602
Query: 550 VIPKYGADALRLW--TALAPPGEDHPFKWETVDYNFR-FLQKVWNIYRFAERH--IKDFD 604
++ YGADALRL+ ++ ED F + V+ + L + N F + + + FD
Sbjct: 603 IMDAYGADALRLYLLNSVVVKAEDLRFSDKGVESVLKQVLLPLSNALAFYKTYAELYGFD 662
Query: 605 YEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVK 664
++ +IEL +DRWILS L+ ++ E + +Y + + FI ++ + YI +
Sbjct: 663 PKETDNIELAEIDRWILSSLYSLVGKTRESMSQYDLHAAVNPFVDFI-EDLTNWYIRRSR 721
Query: 665 YRLY-GDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSW 723
R + +D + A LYE+L ++APF+P I E++Y + + + +SVHL +
Sbjct: 722 RRFWDAEDSADRRAAFSTLYEVLVVFSKVIAPFIPFIAEDMYQQL-RGETDPESVHLCDF 780
Query: 724 PEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIY-ALESYDDLKLIE 782
P ++I E+ + R++V+ + H + + L++V I + E + L +
Sbjct: 781 PHVVLEKILPDLERKMQDIREIVALGHSLRKEHKLKVRQPLQNVYIVGSKERKEALAQVG 840
Query: 783 KDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKNNAESIARE 842
I +N++ + P+ + +KPN++ +G + G +P I L + +
Sbjct: 841 SLIGEELNVKDVHFCSETPEYVTTL--IKPNFRTLGKKVGNRLPEIQRALAGLPQEQIQA 898
Query: 843 IKENGKVEFEIDGEKVELTKEDVMI 867
G++ + E + L KED+ +
Sbjct: 899 FMHKGQMVVSLGEETISLDKEDITV 923
>sp|Q9Z972|SYI_CHLPN ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437565|pir||E72118 isoleucine--tRNA ligase (EC
6.1.1.5) - Chlamydophila pneumoniae (strain CWL029)
>gi|4376371|gb|AAD18262.1| (AE001597) Isoleucyl-tRNA
Synthetase [Chlamydophila pneumoniae CWL029]
>gi|8978483|dbj|BAA98320.1| (AP002545) isoleucyl-tRNA
synthetase [Chlamydophila pneumoniae J138]
Length = 1043
Score = 285 bits (721), Expect = 2e-75
Identities = 249/927 (26%), Positives = 417/927 (44%), Gaps = 96/927 (10%)
Query: 17 KYWLEEKIYKYRLD--ENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRMRGYNV 74
K+W + +I++ L + K Y+ PPF +G H GH+L+ T D++ RY M GY V
Sbjct: 20 KFWKDNQIFEKSLQNRQGKTLYSFYDGPPFATGLPHYGHLLASTIKDVVGRYATMDGYYV 79
Query: 75 LFPQGFDNHGLPTELKVEKEFGITKDQPEE------FLKKCVEWTWQAIEAMRKQFIRIG 128
G+D HG+P E +VEK +T E F ++C + ++ + RIG
Sbjct: 80 PRRFGWDCHGVPVEYEVEKSLSLTAPGAIEDFGIASFNEECRKIVFRYVHEWEYYINRIG 139
Query: 129 YSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVG--YV 186
D+ + TMD + +V Y +GL+Y V + T L+ E Y
Sbjct: 140 RWVDFSSTWKTMDASFMESVWWVFQSLYNQGLVYEGTKVVPFSTALGTPLSNFEASQNYK 199
Query: 187 EEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAV------------------------ 222
E + +++PL + S + + TT P +P+ +A+
Sbjct: 200 EVDDPSLVVRMPLQNDSASLLVWTTTPWTLPSNMAIAVGETLVYVRIQDKKSGEQWILSQ 259
Query: 223 ------FVHPDD----ERY--KHLVGKKVKLPIY-------EREVPILADEDVDPNFGTG 263
F +P++ E + K LVG+ + P E ++A V+ + GTG
Sbjct: 260 GCVSRWFSNPEEFVILESFSGKDLVGRTYEPPFTFFQSKREEGAFRVIAASFVEESEGTG 319
Query: 264 AVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMG 323
V+ E D + K ++P++ ++ G+ E Y G ++ A K+I + L+K G
Sbjct: 320 VVHMAPAFGEGDFLVCKENHVPLVCPVDAHGSFTEEIPQYQGQYIKHADKEIIKFLKKEG 379
Query: 324 LLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDMFL 383
++ +KHR + P+ WF+ V+ D++++ I+W PE +
Sbjct: 380 RIFYHGTVKHRYPFCWRTDT---PLIYKAVNSWFVAVEKIKDKMLRANSSIHWVPEHIQE 436
Query: 384 -RLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPA---RE-EDLPVDPRFD--KPP 436
R W E DW ISR R +GTP P W +G I+ RE E+L D +
Sbjct: 437 GRFGKWLEGAR-DWAISRNRYWGTPIPIWKSADGEILVVGSIRELEELTGTQITDIHRHF 495
Query: 437 VEKCPVC--GAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRP 494
++ + G + V DCW DS P + E +K E FP
Sbjct: 496 IDDLNIVKDGKPFHRIPYVFDCWFDSGAMPYAQNHY------PFENQKETEEAFPADFIA 549
Query: 495 QGTDIIRTWAFYTIFRTFKLTGKKP-WKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPK 553
+G D R W FYT+ + +P +++ ++NG++ DG KMSK N +P V+
Sbjct: 550 EGLDQTRGW-FYTLTVISAILFDRPAFRNAIVNGIILAEDGNKMSKRLNNYPSPKYVLDT 608
Query: 554 YGADALRLWT--ALAPPGEDHPFKWETVDYNFR-FLQKVWNIYRFAERHIKDFDYE-KYK 609
YGADALRL+ ++ ED F + ++ + L + N+ F + + + ++ K +
Sbjct: 609 YGADALRLYLLHSVVVKAEDLRFSDKGIEGVLKQILLPLTNVLSFFNTYAELYGFDPKSQ 668
Query: 610 DIE--LEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRL 667
DIE +D+WILS L+ ++ E + +Y N +TFI ++ + YI + R
Sbjct: 669 DIEPAYTEIDQWILSNLYSVVGKVRESMSQYHLNFAVEPFVTFI-DDLTNWYIRRCRRRF 727
Query: 668 Y-GDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEY 726
+ +D + A LYE+L ++APFVP + E+IY + +K E SVHL +P+
Sbjct: 728 WEAEDTPDRRAAFSTLYEVLTVFCKVIAPFVPFLAEDIYQKLKLEKEPE-SVHLCDFPQV 786
Query: 727 REDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESYDDLKLI---EK 783
D+I EK R++V + H + + L + Y + S D L L+ E
Sbjct: 787 EMDKILPDLEKRMHDIREIVGLGHSLRKEHKLKVRQPLAN--FYVVGSKDRLSLLKTFEG 844
Query: 784 DIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYG---KLVPRIVEHLKNNAESIA 840
IA +N++ + ++ P VKPN++ +G + G K V + + L NNA I
Sbjct: 845 LIAEELNVKNVIFYEEAPSF--IYTTVKPNFRMLGKKVGSKMKEVQKALSELPNNA--ID 900
Query: 841 REIKENGKVEFEIDGEKVELTKEDVMI 867
+ I+E V ID ++ L +DV+I
Sbjct: 901 KLIQEETWV-LTIDDREIALDGDDVVI 926
>pir||C81552 isoleucyl-tRNA synthetase CP0665 [imported] - Chlamydophila
pneumoniae (strain AR39) >gi|7189579|gb|AAF38477.1|
(AE002224) isoleucyl-tRNA synthetase [Chlamydophila
pneumoniae AR39]
Length = 1043
Score = 285 bits (721), Expect = 2e-75
Identities = 249/927 (26%), Positives = 417/927 (44%), Gaps = 96/927 (10%)
Query: 17 KYWLEEKIYKYRLD--ENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRMRGYNV 74
K+W + +I++ L + K Y+ PPF +G H GH+L+ T D++ RY M GY V
Sbjct: 20 KFWKDNQIFEKSLQNRQGKTLYSFYDGPPFATGLPHYGHLLASTIKDVVGRYATMDGYYV 79
Query: 75 LFPQGFDNHGLPTELKVEKEFGITKDQPEE------FLKKCVEWTWQAIEAMRKQFIRIG 128
G+D HG+P E +VEK +T E F ++C + ++ + RIG
Sbjct: 80 PRRFGWDCHGVPVEYEVEKSLSLTAPGAIEDFGIASFNEECRKIVFRYVHEWEYYINRIG 139
Query: 129 YSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVG--YV 186
D+ + TMD + +V Y +GL+Y V + T L+ E Y
Sbjct: 140 RWVDFSSTWKTMDASFMESVWWVFQSLYNQGLVYEGTKVVPFSTALGTPLSNFEASQNYK 199
Query: 187 EEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAV------------------------ 222
E + +++PL + S + + TT P +P+ +A+
Sbjct: 200 EVDDPSLVVRMPLQNDSASLLVWTTTPWTLPSNMAIAVGETLVYVRIQDKKSGEQWILSQ 259
Query: 223 ------FVHPDD----ERY--KHLVGKKVKLPIY-------EREVPILADEDVDPNFGTG 263
F +P++ E + K LVG+ + P E ++A V+ + GTG
Sbjct: 260 GCVSRWFSNPEEFVILESFSGKDLVGRTYEPPFTFFQSKREEGAFRVIAASFVEESEGTG 319
Query: 264 AVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMG 323
V+ E D + K ++P++ ++ G+ E Y G ++ A K+I + L+K G
Sbjct: 320 VVHMAPAFGEGDFLVCKENHVPLVCPVDAHGSFTEEIPQYQGQYIKHADKEIIKFLKKEG 379
Query: 324 LLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDMFL 383
++ +KHR + P+ WF+ V+ D++++ I+W PE +
Sbjct: 380 RIFYYGTVKHRYPFCWRTDT---PLIYKAVNSWFVAVEKIKDKMLRANSSIHWVPEHIQE 436
Query: 384 -RLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPA---RE-EDLPVDPRFD--KPP 436
R W E DW ISR R +GTP P W +G I+ RE E+L D +
Sbjct: 437 GRFGKWLEGAR-DWAISRNRYWGTPIPIWKSADGEILVVGSIRELEELTGTQITDIHRHF 495
Query: 437 VEKCPVC--GAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRP 494
++ + G + V DCW DS P + E +K E FP
Sbjct: 496 IDDLNIVKDGKPFHRIPYVFDCWFDSGAMPYAQNHY------PFENQKETEEAFPADFIA 549
Query: 495 QGTDIIRTWAFYTIFRTFKLTGKKP-WKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPK 553
+G D R W FYT+ + +P +++ ++NG++ DG KMSK N +P V+
Sbjct: 550 EGLDQTRGW-FYTLTVISAILFDRPAFRNAIVNGIILAEDGNKMSKRLNNYPSPKYVLDT 608
Query: 554 YGADALRLWT--ALAPPGEDHPFKWETVDYNFR-FLQKVWNIYRFAERHIKDFDYE-KYK 609
YGADALRL+ ++ ED F + ++ + L + N+ F + + + ++ K +
Sbjct: 609 YGADALRLYLLHSVVVKAEDLRFSDKGIEGVLKQILLPLTNVLSFFNTYAELYGFDPKSQ 668
Query: 610 DIE--LEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRL 667
DIE +D+WILS L+ ++ E + +Y N +TFI ++ + YI + R
Sbjct: 669 DIEPAYTEIDQWILSNLYSVVGKVRESMSQYHLNFAVEPFVTFI-DDLTNWYIRRCRRRF 727
Query: 668 Y-GDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEY 726
+ +D + A LYE+L ++APFVP + E+IY + +K E SVHL +P+
Sbjct: 728 WEAEDTPDRRAAFSTLYEVLTVFCKVIAPFVPFLAEDIYQKLKLEKEPE-SVHLCDFPQV 786
Query: 727 REDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESYDDLKLI---EK 783
D+I EK R++V + H + + L + Y + S D L L+ E
Sbjct: 787 EMDKILPDLEKXMHDIREIVGLGHSLRKEHKLKVRQPLAN--FYVVGSKDRLSLLKTFEG 844
Query: 784 DIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYG---KLVPRIVEHLKNNAESIA 840
IA +N++ + ++ P VKPN++ +G + G K V + + L NNA I
Sbjct: 845 LIAEELNVKNVIFYEEAPSF--IYTTVKPNFRMLGKKVGSKMKEVQKALSELPNNA--ID 900
Query: 841 REIKENGKVEFEIDGEKVELTKEDVMI 867
+ I+E V ID ++ L +DV+I
Sbjct: 901 KLIQEETWV-LTIDDREIALDGDDVVI 926
>gi|6755953 valyl-tRNA synthetase 2 [Mus musculus] >gi|3986754|gb|AAC84151.1|
(AF109905) G7A [Mus musculus]
Length = 1263
Score = 282 bits (715), Expect = 9e-75
Identities = 242/843 (28%), Positives = 373/843 (43%), Gaps = 97/843 (11%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPS-------YAIDTPPPFTSGTLHLGHV 54
+P Y P +E W +W + +K S + + PPP +G+LHLGH
Sbjct: 295 MPDSYSPQYVEAAWYPWWERQGFFKPEYGRPSVSAPNPRGVFMMCIPPPNVTGSLHLGHA 354
Query: 55 LSHTWIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEK----EFGITKDQ--PEEFLKK 108
L++ D + R+ RMRG L+ G D+ G+ T++ VEK E G+ + Q E FL++
Sbjct: 355 LTNAIQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLWKERGLNRHQLGREAFLEE 414
Query: 109 CVEWTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPV 168
+W + + + Q ++G S DWD TMD A V ++ + +++G+IYR V
Sbjct: 415 VWKWKAEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSATVTEAFVRLHEEGVIYRSTRLV 474
Query: 169 YWCPKCRTSLAKAEV--------------GYVE--EEGYL--YYIKLPLADGSGYIPIAT 210
W ++++ EV GY E E G L + K+ +D + +AT
Sbjct: 475 NWSCTLNSAISDIEVDKKELTGRTLLPVPGYKEKVEFGVLVSFAYKVQGSDSDEEVVVAT 534
Query: 211 TRPELMPACVAVFVHPDDERYKHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTY 270
TR E M VAV VHP D RY+HL GK V P R +PI+ D+ VD FGTGAV
Sbjct: 535 TRIETMLGDVAVAVHPKDPRYQHLKGKCVVHPFLSRSLPIVFDDFVDMEFGTGAVKITPA 594
Query: 271 GDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEK 330
D+ D +R+ L I ++ G + P+ GL EARK + L++ G L++ K
Sbjct: 595 HDQNDYEVGQRHRLEAISIMDSKGALINVPPPFLGLPRFEARKAVLAALKERG-LFRGVK 653
Query: 331 IKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTD--EIVKVAKEINWYPEDMFLRLKDW 388
V+ RS + +E L + QW++R + ++ PE W
Sbjct: 654 DNPMVVPLCNRSKDV--VEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRTWHSW 711
Query: 389 AESMDWDWVISRQRVFGTPFP-FWVCKNGHIIPAREED---LPVDPRFDKPPVEKCP-VC 443
+++ DW ISRQ +G P +++ + +P E+ V R + EK
Sbjct: 712 MDNIR-DWCISRQLWWGHRIPAYFITVHDPAVPPGEDPDGRYWVSGRTEAEAREKAAREF 770
Query: 444 GAEIEPVT-----DVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTD 498
G + ++ DVLD W S + P I W E F +P L G D
Sbjct: 771 GVSPDKISLQQDEDVLDTWFSSGLFPFSIFGW----PNQSEDLSVF---YPGTLLETGHD 823
Query: 499 IIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEV-------- 550
I+ W + KLTGK P++++ ++ +V GRKMSKS GNV+ P +V
Sbjct: 824 ILFFWVARMVMLGLKLTGKLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIHGVSLQG 883
Query: 551 -----------------------------IPKYGADALRL-WTALAPPGEDHPFKWETVD 580
IP+ G DALR A G D +
Sbjct: 884 LYDQLLNSNLDPSEVEKAKEGQKADFPAGIPECGTDALRFGLCAYTSQGRDINLDVNRIL 943
Query: 581 YNFRFLQKVWNIYRFAERHI-KDFDYEKYKDIELEP--LDRWILSRLHRIIKFATEELER 637
F K+WN +FA R + K F E +DRWI SRL ++ + E +
Sbjct: 944 GYRHFCNKLWNATKFALRGLGKGFVPSATSKPEGHESLVDRWIRSRLTEAVRLSNEGFQA 1003
Query: 638 YRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFV 697
Y F IT +F +E+ D Y+E +K L G D+ + A+ LY L + LL+PF+
Sbjct: 1004 YDFPAITTAQYSFWLYELCDVYLECLKPVLNGVDQVAAECARQTLYTCLDVGLRLLSPFM 1063
Query: 698 PHITEEIYHAM-FKDKIGEKSVHLLSWPEYRE-DRIDEKAEKLGELARKVVSEMRKYKNS 755
P +TEE++ + + S+ + +PE E D +AE ELA + +R +
Sbjct: 1064 PFVTEELFQRLPRRTPKAPASLCVTPYPEPSECSWKDPEAEAALELALSITRAVRSLRAD 1123
Query: 756 HGM 758
+ +
Sbjct: 1124 YNL 1126
>gb|AAD26531.1|AF087141_1 (AF087141) valyl-tRNA synthetase [Mus musculus]
>gi|4590330|gb|AAD26532.1|AF087680_1 (AF087680)
valyl-tRNA synthetase [Mus musculus]
Length = 1263
Score = 280 bits (710), Expect = 3e-74
Identities = 241/843 (28%), Positives = 372/843 (43%), Gaps = 97/843 (11%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPS-------YAIDTPPPFTSGTLHLGHV 54
+P Y P +E W +W + +K S + + PPP +G+LHLGH
Sbjct: 295 MPDSYSPQYVEAAWYPWWERQGFFKPEYGRPSVSAPNPRGVFMMCIPPPNVTGSLHLGHA 354
Query: 55 LSHTWIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEK----EFGITKDQ--PEEFLKK 108
L++ D + R+ RMRG L+ G D+ G+ T++ VEK E G+ + Q E FL++
Sbjct: 355 LTNAIQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLWKERGLNRHQLGREAFLEE 414
Query: 109 CVEWTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPV 168
+W + + + Q ++G S DWD TMD A V ++ + +++G+IYR V
Sbjct: 415 VWKWKAEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSATVTEAFVRLHEEGVIYRSTRLV 474
Query: 169 YWCPKCRTSLAKAEV--------------GYVE--EEGYL--YYIKLPLADGSGYIPIAT 210
W ++++ EV GY E E G L + K+ +D + +AT
Sbjct: 475 NWSCTLNSAISDIEVDKKELTGRTLLPVPGYKEKVEFGVLVSFAYKVQGSDSDEEVVVAT 534
Query: 211 TRPELMPACVAVFVHPDDERYKHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTY 270
TR E M VAV VHP D RY+HL GK V P R +PI+ D+ VD FGTGAV
Sbjct: 535 TRIETMLGDVAVAVHPKDPRYQHLKGKCVVHPFLSRSLPIVFDDFVDMEFGTGAVKITPA 594
Query: 271 GDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEK 330
D+ D +R+ L I ++ G + P+ GL EARK + L++ G L++ K
Sbjct: 595 HDQNDYEVGQRHRLEAISIMDSKGALINVPPPFLGLPRFEARKAVLAALKERG-LFRGVK 653
Query: 331 IKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTD--EIVKVAKEINWYPEDMFLRLKDW 388
V+ RS + +E L + QW++R + ++ PE W
Sbjct: 654 DNPMVVPLCNRSKDV--VEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRTWHSW 711
Query: 389 AESMDWDWVISRQRVFGTPFP-FWVCKNGHIIPAREED---LPVDPRFDKPPVEKCP-VC 443
+++ DW ISRQ +G P +++ + +P E+ V R + EK
Sbjct: 712 MDNIR-DWCISRQLWWGHRIPAYFITVHDPAVPPGEDPDGRYWVSGRTEAEAREKAAREF 770
Query: 444 GAEIEPVT-----DVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTD 498
G + ++ DVLD W S + P I W E F +P L G D
Sbjct: 771 GVSPDKISLQQDEDVLDTWFSSGLFPFSIFGW----PNQSEDLSVF---YPGTLLETGHD 823
Query: 499 IIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEV-------- 550
I+ W + KLTGK P++++ ++ +V GRKMSKS GNV+ P +V
Sbjct: 824 ILFFWVARMVMLGLKLTGKLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIHGVSLQG 883
Query: 551 -----------------------------IPKYGADALRL-WTALAPPGEDHPFKWETVD 580
IP+ G DALR A G D +
Sbjct: 884 LYDQLLNSNLDPSEVEKAKEGQKADFPAGIPECGTDALRFGLCAYTSQGRDINLDVNRIL 943
Query: 581 YNFRFLQKVWNIYRFAERHI-KDFDYEKYKDIELEP--LDRWILSRLHRIIKFATEELER 637
F K+WN +F R + K F E +DRWI SRL ++ + E +
Sbjct: 944 GYRHFCNKLWNATKFRLRGLGKGFVPSATSKPEGHESLVDRWIRSRLTEAVRLSNEGFQA 1003
Query: 638 YRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFV 697
Y F IT +F +E+ D Y+E +K L G D+ + A+ LY L + LL+PF+
Sbjct: 1004 YDFPAITTAQYSFWLYELCDVYLECLKPVLNGVDQVAAECARQTLYTCLDVGLRLLSPFM 1063
Query: 698 PHITEEIYHAM-FKDKIGEKSVHLLSWPEYRE-DRIDEKAEKLGELARKVVSEMRKYKNS 755
P +TEE++ + + S+ + +PE E D +AE ELA + +R +
Sbjct: 1064 PFVTEELFQRLPRRTPKAPASLCVTPYPEPSECSWKDPEAEAALELALSITRAVRSLRAD 1123
Query: 756 HGM 758
+ +
Sbjct: 1124 YNL 1126
>gb|AAA81332.1| (M98326) valyl-tRNA synthetase [Homo sapiens]
Length = 1063
Score = 280 bits (709), Expect = 4e-74
Identities = 240/843 (28%), Positives = 377/843 (44%), Gaps = 97/843 (11%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPS-------YAIDTPPPFTSGTLHLGHV 54
+P Y P +E W +W ++ +K S + + PPP +G+LHLGH
Sbjct: 96 MPDSYSPRYVEAAWYPWWEQQGFFKPEYGRPNVSAGNPRGVFMMCIPPPNVTGSLHLGHA 155
Query: 55 LSHTWIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEK----EFGITKDQ--PEEFLKK 108
L++ D + R+ RMRG L+ G D+ G+ T++ VEK E G+++ Q E FL++
Sbjct: 156 LTNAIQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLWREQGLSRHQLGREAFLQE 215
Query: 109 CVEWTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPV 168
+W + + + Q ++G S DWD TMD AAV ++ + +++G+IYR V
Sbjct: 216 VWKWKEEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAAVTEAFVRLHEEGIIYRSTRLV 275
Query: 169 YWCPKCRTSLAKAEV--------------GYVE--EEGYL--YYIKLPLADGSGYIPIAT 210
W ++++ EV GY E E G L + K+ +D + +AT
Sbjct: 276 NWSCTLNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGVLVSFAYKVQGSDSDEEVVVAT 335
Query: 211 TRPELMPACVAVFVHPDDERYKHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTY 270
TR E M VAV VHP D RY+HL GK V P R +PI+ DE VD +FGTGAV
Sbjct: 336 TRIETMLGDVAVAVHPKDTRYQHLKGKNVIHPFLSRSLPIVFDEFVDMDFGTGAVKITPA 395
Query: 271 GDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEK 330
D+ D +R+ L I ++ G + P+ GL EARK + L++ G L++ +
Sbjct: 396 HDQNDYEVGQRHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKERG-LFRGIE 454
Query: 331 IKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTD--EIVKVAKEINWYPEDMFLRLKDW 388
V+ RS + +E L + QW++R + ++ PE W
Sbjct: 455 DNPMVVPLCNRSKDV--VEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRTWHAW 512
Query: 389 AESMDWDWVISRQRVFGTPFP-FWVCKNGHIIPAREED---LPVDPRFDKPPVEK-CPVC 443
+++ +W ISRQ +G P ++V + +P E+ V R + EK
Sbjct: 513 MDNIR-EWCISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGRNEAEAREKAAKEF 571
Query: 444 GAEIEPVT-----DVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTD 498
G + ++ DVLD W S + PL I W E F +P L G D
Sbjct: 572 GVSPDKISLQQDEDVLDTWFSSGLFPLSILGW----PNQSEDLSVF---YPGTLLETGHD 624
Query: 499 IIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEV-------- 550
I+ W + KLTG+ P++++ ++ +V GRKMSKS GNV+ P +V
Sbjct: 625 ILFFWVARMVMLGLKLTGRLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIYGISLQG 684
Query: 551 -----------------------------IPKYGADALRL-WTALAPPGEDHPFKWETVD 580
IP+ G DALR A G D +
Sbjct: 685 LHNQLLNSNLDPSEVEKAKEGQKADFPAGIPECGTDALRFGLCAYMSQGRDINLDVNRIL 744
Query: 581 YNFRFLQKVWNIYRFAERHI-KDF--DYEKYKDIELEPLDRWILSRLHRIIKFATEELER 637
F K+WN +FA R + K F +DRWI SRL ++ + + +
Sbjct: 745 GYRHFCNKLWNATKFALRGLGKGFVPSPTSQPGGHESLVDRWIRSRLTEAVRLSNQGFQA 804
Query: 638 YRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFV 697
Y F +T +F +E+ D Y+E +K L G D+ + A+ LY L + LL+PF+
Sbjct: 805 YDFPAVTTAQYSFWLYELCDVYLECLKPVLNGVDQVAAECARQTLYTCLDVGLRLLSPFI 864
Query: 698 PHITEEIYHAM-FKDKIGEKSVHLLSWPEYRE-DRIDEKAEKLGELARKVVSEMRKYKNS 755
P +TEE++ + + S+ + +PE E D +AE ELA + +R +
Sbjct: 865 PFVTEELFQRLPRRMPQAPPSLCVTPYPEPSECSWKDPEAEAALELALSITRAVRSLRAD 924
Query: 756 HGM 758
+ +
Sbjct: 925 YNL 927
>sp|P26640|SYV_HUMAN VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
Length = 1263
Score = 280 bits (709), Expect = 4e-74
Identities = 240/843 (28%), Positives = 377/843 (44%), Gaps = 97/843 (11%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPS-------YAIDTPPPFTSGTLHLGHV 54
+P Y P +E W +W ++ +K S + + PPP +G+LHLGH
Sbjct: 296 MPDSYSPRYVEAAWYPWWEQQGFFKPEYGRPNVSAGNPRGVFMMCIPPPNVTGSLHLGHA 355
Query: 55 LSHTWIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEK----EFGITKDQ--PEEFLKK 108
L++ D + R+ RMRG L+ G D+ G+ T++ VEK E G+++ Q E FL++
Sbjct: 356 LTNAIQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLWREQGLSRHQLGREAFLQE 415
Query: 109 CVEWTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPV 168
+W + + + Q ++G S DWD TMD AAV ++ + +++G+IYR V
Sbjct: 416 VWKWKEEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAAVTEAFVRLHEEGIIYRSTRLV 475
Query: 169 YWCPKCRTSLAKAEV--------------GYVE--EEGYL--YYIKLPLADGSGYIPIAT 210
W ++++ EV GY E E G L + K+ +D + +AT
Sbjct: 476 NWSCTLNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGVLVSFAYKVQGSDSDEEVVVAT 535
Query: 211 TRPELMPACVAVFVHPDDERYKHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTY 270
TR E M VAV VHP D RY+HL GK V P R +PI+ DE VD +FGTGAV
Sbjct: 536 TRIETMLGDVAVAVHPKDTRYQHLKGKNVIHPFLSRSLPIVFDEFVDMDFGTGAVKITPA 595
Query: 271 GDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEK 330
D+ D +R+ L I ++ G + P+ GL EARK + L++ G L++ +
Sbjct: 596 HDQNDYEVGQRHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKERG-LFRGIE 654
Query: 331 IKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTD--EIVKVAKEINWYPEDMFLRLKDW 388
V+ RS + +E L + QW++R + ++ PE W
Sbjct: 655 DNPMVVPLCNRSKDV--VEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRTWHAW 712
Query: 389 AESMDWDWVISRQRVFGTPFP-FWVCKNGHIIPAREED---LPVDPRFDKPPVEK-CPVC 443
+++ +W ISRQ +G P ++V + +P E+ V R + EK
Sbjct: 713 MDNIR-EWCISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGRNEAEAREKAAKEF 771
Query: 444 GAEIEPVT-----DVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTD 498
G + ++ DVLD W S + PL I W E F +P L G D
Sbjct: 772 GVSPDKISLQQDEDVLDTWFSSGLFPLSILGW----PNQSEDLSVF---YPGTLLETGHD 824
Query: 499 IIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEV-------- 550
I+ W + KLTG+ P++++ ++ +V GRKMSKS GNV+ P +V
Sbjct: 825 ILFFWVARMVMLGLKLTGRLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIYGISLQG 884
Query: 551 -----------------------------IPKYGADALRL-WTALAPPGEDHPFKWETVD 580
IP+ G DALR A G D +
Sbjct: 885 LHNQLLNSNLDPSEVEKAKEGQKADFPAGIPECGTDALRFGLCAYMSQGRDINLDVNRIL 944
Query: 581 YNFRFLQKVWNIYRFAERHI-KDF--DYEKYKDIELEPLDRWILSRLHRIIKFATEELER 637
F K+WN +FA R + K F +DRWI SRL ++ + + +
Sbjct: 945 GYRHFCNKLWNATKFALRGLGKGFVPSPTSQPGGHESLVDRWIRSRLTEAVRLSNQGFQA 1004
Query: 638 YRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFV 697
Y F +T +F +E+ D Y+E +K L G D+ + A+ LY L + LL+PF+
Sbjct: 1005 YDFPAVTTAQYSFWLYELCDVYLECLKPVLNGVDQVAAECARQTLYTCLDVGLRLLSPFI 1064
Query: 698 PHITEEIYHAM-FKDKIGEKSVHLLSWPEYRE-DRIDEKAEKLGELARKVVSEMRKYKNS 755
P +TEE++ + + S+ + +PE E D +AE ELA + +R +
Sbjct: 1065 PFVTEELFQRLPRRMPQAPPSLCVTPYPEPSECSWKDPEAEAALELALSITRAVRSLRAD 1124
Query: 756 HGM 758
+ +
Sbjct: 1125 YNL 1127
>gi|5454158 valyl-tRNA synthetase 2 [Homo sapiens] >gi|11417740|ref|XP_004185.1|
valyl-tRNA synthetase 2 [Homo sapiens]
>gi|4529896|gb|AAD21819.1| (AF134726) G7A [Homo sapiens]
Length = 1264
Score = 279 bits (707), Expect = 8e-74
Identities = 241/843 (28%), Positives = 377/843 (44%), Gaps = 97/843 (11%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYA-------IDTPPPFTSGTLHLGHV 54
+P Y P +E W +W ++ +K S A + PPP +G+LHLGH
Sbjct: 296 MPDSYSPRYVEAAWYPWWEQQGFFKPEYGRPNVSAANPRGVFMMCIPPPNVTGSLHLGHA 355
Query: 55 LSHTWIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEK----EFGITKDQ--PEEFLKK 108
L++ D + R+ RMRG L+ G D+ G+ T++ VEK E G+++ Q E FL++
Sbjct: 356 LTNAIQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLWREQGLSRHQLGREAFLQE 415
Query: 109 CVEWTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPV 168
+W + + + Q ++G S DWD TMD AAV ++ + +++G+IYR V
Sbjct: 416 VWKWKEEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAAVTEAFVRLHEEGIIYRSTRLV 475
Query: 169 YWCPKCRTSLAKAEV--------------GYVE--EEGYL--YYIKLPLADGSGYIPIAT 210
W ++++ EV GY E E G L + K+ +D + +AT
Sbjct: 476 NWSCTLNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGVLVSFAYKVQGSDSDEEVVVAT 535
Query: 211 TRPELMPACVAVFVHPDDERYKHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTY 270
TR E M VAV VHP D RY+HL GK V P R +PI+ DE VD +FGTGAV
Sbjct: 536 TRIETMLGDVAVAVHPKDTRYQHLKGKNVIHPFLSRSLPIVFDEFVDMDFGTGAVKITPA 595
Query: 271 GDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEK 330
D+ D +R+ L I ++ G + P+ GL EARK + L++ G L++ +
Sbjct: 596 HDQNDYEVGQRHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKERG-LFRGIE 654
Query: 331 IKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTD--EIVKVAKEINWYPEDMFLRLKDW 388
V+ RS + +E L + QW++R + ++ PE W
Sbjct: 655 DNPMVVPLCNRSKDV--VEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRTWHAW 712
Query: 389 AESMDWDWVISRQRVFGTPFP-FWVCKNGHIIPAREED---LPVDPRFDKPPVEK-CPVC 443
+++ +W ISRQ +G P ++V + +P E+ V R + EK
Sbjct: 713 MDNIR-EWCISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGRNEAEAREKAAKEF 771
Query: 444 GAEIEPVT-----DVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTD 498
G + ++ DVLD W S + PL I W E F +P L G D
Sbjct: 772 GVSPDKISLQQDEDVLDTWFSSGLFPLSILGW----PNQSEDLSVF---YPGTLLETGHD 824
Query: 499 IIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEV-------- 550
I+ W + KLTG+ P++++ ++ +V GRKMSKS GNV+ P +V
Sbjct: 825 ILFFWVARMVMLGLKLTGRLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIYGISLQG 884
Query: 551 -----------------------------IPKYGADALRL-WTALAPPGEDHPFKWETVD 580
IP+ G DALR A G D +
Sbjct: 885 LHNQLLNSNLDPSEVEKAKEGQKADFPAGIPECGTDALRFGLCAYMSQGRDINLDVNRIL 944
Query: 581 YNFRFLQKVWNIYRFAERHI-KDF--DYEKYKDIELEPLDRWILSRLHRIIKFATEELER 637
F K+WN +FA R + K F +DRWI SRL ++ + + +
Sbjct: 945 GYRHFCNKLWNATKFALRGLGKGFVPSPTSQPGGHESLVDRWIRSRLTEAVRLSNQGFQA 1004
Query: 638 YRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFV 697
Y F +T +F +E+ D Y+E +K L G D+ + A+ LY L + LL+PF+
Sbjct: 1005 YDFPAVTTAQYSFWLYELCDVYLECLKPVLNGVDQVAAECARQTLYTCLDVGLRLLSPFM 1064
Query: 698 PHITEEIYHAM-FKDKIGEKSVHLLSWPEYRE-DRIDEKAEKLGELARKVVSEMRKYKNS 755
P +TEE++ + + S+ + +PE E D +AE ELA + +R +
Sbjct: 1065 PFVTEELFQRLPRRMPQAPPSLCVTPYPEPSECSWKDPEAEAALELALSITRAVRSLRAD 1124
Query: 756 HGM 758
+ +
Sbjct: 1125 YNL 1127
>sp|P43824|SYI_HAEIN ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437547|pir||S78633 isoleucine--tRNA ligase (EC
6.1.1.5) - Haemophilus influenzae (strain Rd KW20)
Length = 941
Score = 279 bits (705), Expect = 1e-73
Identities = 214/775 (27%), Positives = 353/775 (44%), Gaps = 87/775 (11%)
Query: 3 PKKYDPNEIEPKWQKYWLEEKIYKY--RLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWI 60
P + D + EP K W E+ +Y+ + + K S+ + PP+ +G +H+GH ++
Sbjct: 17 PMRGDLAKREPDKXKNWYEKNLYQKIRKASKGKKSFILHDGPPYANGNIHIGHAVNKILK 76
Query: 61 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQ--PEEFLKKCVEWTWQAIE 118
DII + K G++ + G+D HGLP ELKVE G ++ EF +KC E+ + +E
Sbjct: 77 DIIIKSKTALGFDSPYIPGWDCHGLPIELKVEGLVGKPNEKISAAEFRQKCREYAAEQVE 136
Query: 119 AMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSL 178
+K FIR+G DWD Y TM+ +A + ++L + + G +Y+ PV+WC C +SL
Sbjct: 137 GQKKDFIRLGVLGDWDNPYLTMNFDTEANIIRTLGKVIENGHLYKGSKPVHWCLDCGSSL 196
Query: 179 AKAEVGYVEEEGYLYYIKLPL-----------ADGSGYIPIA----TTRPELMPACVAVF 223
A+AEV Y ++ Y++ P A G G ++ TT P MP+ A+
Sbjct: 197 AEAEVEYEDKVSPSIYVRFPAESADEIEAKFSAQGRGQGKLSAIIWTTTPWTMPSNRAIA 256
Query: 224 VHPD---------DERY----------------KHLV------GKKVKL-----PIYERE 247
V+ D DER +H+ G ++L P Y+
Sbjct: 257 VNADLEYNLVQLGDERVILAAELVESVAKAVGIEHIEILGSVKGDDLELSRFHHPFYDFT 316
Query: 248 VPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLK 307
VP++ + V + GTG V+ D + K+Y+LP+ ++ DG +AG
Sbjct: 317 VPVILGDHVTTDGGTGLVHTAPDHGLDDFIVGKQYDLPMAGLVSNDGKFISTTEFFAGKG 376
Query: 308 VEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFI--RVKDFTD 365
V EA + E L+++G L K EKIKH H R PI QWFI +
Sbjct: 377 VFEANPLVIEKLQEVGNLLKVEKIKHSY-PHCWRHK--TPIIFRATPQWFIGMETQGLRQ 433
Query: 366 EIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPAREED 425
+ + K++ W P+ R++ E+ DW ISRQR +G P +V K + R D
Sbjct: 434 QALGEIKQVRWIPDWGQARIEKMVENRP-DWCISRQRTWGVPMTLFVHKETEELHPRTLD 492
Query: 426 L--PVDPRFDKPPVE------KCPVCGAEIEP---VTDVLDCWVDSSITPLIITRWHEAI 474
L V R ++ ++ + + GA+ E V D LD W DS T +
Sbjct: 493 LLEEVAKRVERAGIQAWWDLDEKELLGADAETYRKVPDTLDVWFDSGSTYSSVVANRLEF 552
Query: 475 KGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDG 534
G + + +G+D R W ++ + K P+K ++ +G G
Sbjct: 553 NGQD-----------IDMYLEGSDQHRGWFMSSLMLSTATDSKAPYKQVLTHGFTVDGQG 601
Query: 535 RKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYR 594
RKMSKS GN+V P EV+ K+G D LRLW A + E + +++ N R
Sbjct: 602 RKMSKSIGNIVTPQEVMDKFGGDILRLWVASTDYTGEMTVSDEILKRAADSYRRIRNTAR 661
Query: 595 FAERHIKDFDYEK--YKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIW 652
F ++ FD ++ K ++ LDRW ++ + + Y+F+ + + LM F
Sbjct: 662 FLLANLNGFDPKRDLVKPEKMISLDRWAVACALDAQNEIKDAYDNYQFHTVVQRLMRFCS 721
Query: 653 HEVADDYIEMVKYRLYGD--DEESKLKAKVALYELLYNVMLLLAPFVPHITEEIY 705
E+ Y++++K R Y D ++ + AL+ + ++ +AP + +EI+
Sbjct: 722 VEMGSFYLDIIKDRQYTTKADSLARRSCQTALWHIAEALVRWMAPILSFTADEIW 776
>sp|Q9ZHB3|SYI_STRPN ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|4009476|gb|AAC95446.1| (AF068901) isoleucine-tRNA
synthetase [Streptococcus pneumoniae]
Length = 930
Score = 277 bits (700), Expect = 5e-73
Identities = 238/865 (27%), Positives = 380/865 (43%), Gaps = 107/865 (12%)
Query: 12 EPKWQKYWLEEKIYKYR--LDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRM 69
EP WQK W + K+Y+ R L++ KP + + PP+ +G +H+GH ++ DII R K M
Sbjct: 24 EPVWQKEWEDAKLYQRRQELNQGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSM 83
Query: 70 RGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPE--EFLKKCVEWTWQAIEAMRKQFIRI 127
G+ F G+D HGLP E + K+ G+ + + + E+LK C E+ ++ R+ F R+
Sbjct: 84 SGFYAPFIPGWDTHGLPIEQVLSKQ-GVKRKEMDLVEYLKLCREYALSQVDKQREDFKRL 142
Query: 128 GYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVGYVE 187
G S DW+ Y T+ Y+AA + E KG IYR PVYW ++LA+AE+ Y +
Sbjct: 143 GVSGDWENPYVTLTPDYEAAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHD 202
Query: 188 EEGYLYYIKLPLADGSG------YIPIATTRPELMPACVA---------VFVHPDDERYK 232
Y + DG G YI + TT P + A V V P E K
Sbjct: 203 LVSTSLYYANKVKDGKGVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPVGEARK 262
Query: 233 HLVGKKVKLPIYER-------------------------------EVPILADEDVDPNFG 261
+V ++ + E+ E+ IL D V + G
Sbjct: 263 FVVAAELLTSLSEKFGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDH-VTTDSG 321
Query: 262 TGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGP-YAGLKVEEARKKIAEDLE 320
TG V+ E D NL V + ++E G M +NAGP + G E K + +E
Sbjct: 322 TGIVHTAPGFGEDDYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYE---KVVPTVIE 378
Query: 321 KMG-LLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPE 379
K+G LL +E+I H + PI QWF V F EI+ +++ ++ E
Sbjct: 379 KLGNLLLAQEEISH---SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSE 435
Query: 380 DMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVDPRFDK----- 434
+RL + DWVISRQR +G P P + ++G I E V F+K
Sbjct: 436 WGKVRLYNMIRDRG-DWVISRQRTWGVPLPIFYAEDGTAIMVAETIEHVAQLFEKHGSSI 494
Query: 435 ----------PPVEKCPVC-GAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKW 483
P P E + TD++D W DS + W+ + E
Sbjct: 495 WWERDAKDLLPEGFTHPGSPNGEFKKETDIMDVWFDSG------SSWNGVVVNRPEL--- 545
Query: 484 FEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGN 543
+P L +G+D R W ++ + G P+K I+ G G KMSKS GN
Sbjct: 546 ---TYPADLYLEGSDQYRGWFNSSLITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGN 602
Query: 544 VVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDF 603
+AP +V ++GA+ LRLW D + + +K+ N RF + DF
Sbjct: 603 TIAPSDVEKQFGAEILRLWVTSVDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDF 662
Query: 604 D--YEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIE 661
+ + EL +D+++ R ++++K + + F I + L+ FI +++ Y++
Sbjct: 663 NPAQDTVAYDELRSVDKYMTIRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLD 722
Query: 662 MVKYRLYGDDEES--KLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVH 719
K +Y + +S + + + Y++L + LL P +PH EEI+ + + E V
Sbjct: 723 FAKDVVYIEGAKSLERRQMQTVFYDILVKITKLLTPILPHTAEEIW--SYLEFETEDFVQ 780
Query: 720 LLSWPEY-----REDRIDEKAEKLG--ELARKVVSEMRKYKNSHGMPLNAKLEHVAIYAL 772
L PE +E+ +D A + A+K + E R K G L A H+ +Y
Sbjct: 781 LSELPEVQTFANQEEILDTWAAFMDFRGQAQKALEEARNAK-VIGKSLEA---HLTVYPN 836
Query: 773 ESYDD-LKLIEKDIAGTMNIEKLEI 796
E L+ + ++A + + +L I
Sbjct: 837 EVVKTLLEAVNSNVAQLLIVSELTI 861
>sp|P49696|SYV_FUGRU VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|1041396|emb|CAA62967.1| (X91856) valyl-tRNA
synthetase [Fugu rubripes]
Length = 1217
Score = 275 bits (697), Expect = 1e-72
Identities = 227/794 (28%), Positives = 338/794 (41%), Gaps = 98/794 (12%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYR-----LDENKPS--YAIDTPPPFTSGTLHLGHV 54
LP Y P +E W +W ++ +K + E P + + PPP +G+LHLGH
Sbjct: 245 LPDSYSPQYVEAAWYPWWEKQGFFKPEFGRKSIGEQNPRGIFMMCIPPPNVTGSLHLGHA 304
Query: 55 LSHTWIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKK 108
L++ D + R+ RMRG L+ G D+ G+ T++ VEK+ K E+F+++
Sbjct: 305 LTNAIQDTLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLMREKGTSRHDLGREKFIEE 364
Query: 109 CVEWTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPV 168
+W + + + Q ++G S DWD TMD AVQ++ + + +G+IYR + V
Sbjct: 365 VWKWKNEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSYAVQEAFIRMHDEGVIYRSKRLV 424
Query: 169 YWCPKCRTSLAKAEV--------------GYVE--EEGYLYYIKLPLADGSGYIPIATTR 212
W ++++ EV GY E E G L + + +ATTR
Sbjct: 425 NWSCSLNSAISDIEVDKNELSGRTLLPVPGYKEKVEFGVLVSFAYKVDGSDEEVVVATTR 484
Query: 213 PELMPACVAVFVHPDDERYKHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGD 272
E M AV VHP D RY+HL GK V P +R++P++ D+ VD +FGTGAV D
Sbjct: 485 IETMLGDTAVAVHPSDSRYQHLKGKTVLHPFCDRKIPVVFDDFVDMSFGTGAVKITPAHD 544
Query: 273 EQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIK 332
D R+NL I ++E+G + P+ G+K +ARK + + L+ +K+ K
Sbjct: 545 HNDYEVGVRHNLAFINILDENGFVINVPPPFLGMKRFDARKAVLQALKDRD-QFKEIKDN 603
Query: 333 HRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKE--INWYPEDMFLRLKDWAE 390
V+ RS + +E L K QW++ D + +E + P+ +W +
Sbjct: 604 PMVVPVCSRSKDI--VEPLMKPQWYVSCSDMGKQAADAVREGRLKIIPDHHSQTWFNWMD 661
Query: 391 SMDWDWVISRQRVFGTPFP--FWVCKNGHIIPAREED--------LPVDPRFDKPPVEKC 440
++ DW ISRQ +G P F + + P + D P + R
Sbjct: 662 NIR-DWCISRQLWWGHRIPAYFITVSDPSVKPGEDMDGHYRVSGRTPEEAREKAAKRFNV 720
Query: 441 PVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDII 500
+ DVLD W S I P I W + E F +P L G DI+
Sbjct: 721 SPDKIALRQDEDVLDTWFSSGINPFSILGW----PNETEDLNVF---YPGTLLETGHDIL 773
Query: 501 RTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAP------------- 547
W + KLTGK P+K++ +V GRKMSKS GNV+ P
Sbjct: 774 FFWVARMVMMGLKLTGKLPFKEVYHCAVVRDAHGRKMSKSLGNVIDPLDDHIGIALEGLH 833
Query: 548 ------------------------DEVIPKYGADALRL-WTALAPPGEDHPFKWETVDYN 582
IP+ G DALR A G D +
Sbjct: 834 AQLMDTNLDPLEVEKPKKVQKADYPNCIPECGTDALRFALCAYTSQGRDINLDVNRILGY 893
Query: 583 FRFLQKVWNIYRFAERHIKD-FDYEKYKDIELEP--LDRWILSRLHRIIKFATEELERYR 639
F K+WN +FA R + D F E E DRWILSRL + Y
Sbjct: 894 RHFCNKLWNAVKFAMRTLGDQFVPADTSPAEREESVSDRWILSRLSTAVAQCDAAFRTYD 953
Query: 640 FNLITRELMTFIWHEVADDYIE-----MVKYRLYGDDEESKLKAKVALYELLYNVMLLLA 694
F IT + F +E+ D Y+E +K + G E + LY L + LLA
Sbjct: 954 FPAITTAIYNFWLYELCDVYLESVKPVFIKAKEDGSCERPAAVCRQTLYTCLEVGLRLLA 1013
Query: 695 PFVPHITEEIYHAM 708
P +P +TEE+Y +
Sbjct: 1014 PLMPFVTEELYQRL 1027
>pir||PN0474 valine--tRNA ligase (EC 6.1.1.9) (version 2) - human (fragment)
Length = 1051
Score = 273 bits (691), Expect = 6e-72
Identities = 227/790 (28%), Positives = 356/790 (44%), Gaps = 94/790 (11%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYK--YRL----DENKPSYAIDTPPPFTSGTLHLGHVL 55
+P Y P +E W +W ++ +K Y L + + + PPP +G+LHLGH L
Sbjct: 96 MPDSYSPRYVEAAWYPWWEQQGFFKPEYGLLMCQQNPRGVFMMCIPPPNVTGSLHLGHAL 155
Query: 56 SHTWIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEF----GITKDQ-PEEFLKKCV 110
++ D + R+ RMRG L+ G D+ G+ T++ VEK+ G+++ Q E FL++
Sbjct: 156 TNAIQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLWRDEGLSRHQLVEAFLQEVW 215
Query: 111 EWTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYW 170
+W + + + Q ++G S DWD TMD AAV ++ + +++G+IYR V W
Sbjct: 216 KWKEEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAAVTEAFVRLHEEGIIYRSTRLVNW 275
Query: 171 CPKCRTSLAKAEV--------------GYVE--EEGYL--YYIKLPLADGSGYIPIATTR 212
++++ EV GY E E G L + K+ +D + +ATTR
Sbjct: 276 SCTLNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGVLVPFAYKVQGSDSDEEVVVATTR 335
Query: 213 PELMPACVAVFVHPDDERYKHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGD 272
E M VAV VHP D RY+HL GK V P R +PI+ DE VD +FGTGAV D
Sbjct: 336 IETMLGDVAVAVHPKDTRYQHLKGKNVIHPFLSRSLPIVFDEFVDMDFGTGAVKITPAHD 395
Query: 273 EQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIK 332
+ D +R+ L I ++ G + P+ GL EARK + L++ G L++ +
Sbjct: 396 QNDYEVGQRHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKERG-LFRGIEDN 454
Query: 333 HRVLRHTERSSCMAPIELLPKKQWFIRVKDFTD--EIVKVAKEINWYPEDMFLRLKDWAE 390
V+ RS + +E L + QW++R + ++ PE W +
Sbjct: 455 PMVVPLCNRSKDV--VEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRTWHAWMD 512
Query: 391 SMDWDWVISRQRVFGTPFP-FWVCKNGHIIPAREED---LPVDPRFDKPPVEK-CPVCGA 445
++ +W ISRQ +G P ++V + +P E+ V R + EK G
Sbjct: 513 NIR-EWCISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGRNEAEAREKAAKEFGV 571
Query: 446 EIEPVT-----DVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDII 500
+ ++ DVLD W S + PL I W E F +P L G DI+
Sbjct: 572 SPDKISLQQDEDVLDTWFSSGLFPLSILGW----PNQSEDLSVF---YPGTLLETGHDIL 624
Query: 501 RTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEV---------- 550
W + KLTG+ P++++ ++ +V GRKMSKS GNV+ P +V
Sbjct: 625 FFWVARMVMLGLKLTGRLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIYGISLQRLL 684
Query: 551 ----------------------------IPKYGADALRL-WTALAPPGEDHPFKWETVDY 581
IP+ G DALR A G D +
Sbjct: 685 HNQLLNSNLDPSEVEKPKKRDRKLTPSGIPECGTDALRFGLCAYMSQGRDINLDVNRILG 744
Query: 582 NFRFLQKVWNIYRFAERHI-KDF--DYEKYKDIELEPLDRWILSRLHRIIKFATEELERY 638
F K+WN +FA R + K F +DRWI SRL ++ + + + Y
Sbjct: 745 YRHFCNKLWNATKFALRGLGKGFLPSPTSQPGGHESLVDRWIRSRLTEAVRLSNQGFQAY 804
Query: 639 RFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVP 698
F +T + +E+ D Y+E +K L G D+ + A+ LY L + LL+ F+P
Sbjct: 805 DFPAVTTSQYSLWLYELCDVYLECLKPVLNGVDQVAAECARQTLYTCLDVAVRLLSTFIP 864
Query: 699 HITEEIYHAM 708
+TEE++ +
Sbjct: 865 FVTEELFQRL 874
>gi|11429025 isoleucine-tRNA synthetase [Homo sapiens]
>gi|730870|sp|P41252|SYI_HUMAN ISOLEUCYL-TRNA
SYNTHETASE, CYTOPLASMIC (ISOLEUCINE--TRNA LIGASE)
(ILERS) (IRS) >gi|2135522|pir||I59314 isoleucine--tRNA
ligase (EC 6.1.1.5) - human >gi|551622|dbj|BAA05835.1|
(D28473) isoleucyl-tRNA synthetase [Homo sapiens]
Length = 1266
Score = 269 bits (680), Expect = 1e-70
Identities = 242/954 (25%), Positives = 414/954 (43%), Gaps = 119/954 (12%)
Query: 12 EPKWQKYWLEEKIYKYRLDENK--PSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRM 69
E K ++W E ++ L ++K P + PPF +G H GH+L+ T DI+ RY
Sbjct: 19 EEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQ 78
Query: 70 RGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCVEWTWQAIEAMRKQ 123
G++V G+D HGLP E +++K GI + E+ +C + +
Sbjct: 79 SGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQCRAIVMRYSAEWKST 138
Query: 124 FIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV 183
R+G D+D +Y T+ + +V + Y KGL+YR + + C T L+ E
Sbjct: 139 VSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFES 198
Query: 184 --GYVEEEGYLYYIKLPLADGSGYIPIA-TTRPELMPACVAVFVHPDDERYK-------- 232
Y + + ++ PL + +A TT P +P+ +AV V+P+ + K
Sbjct: 199 HQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGR 258
Query: 233 ----------------------------HLVGKKVKLPIYEREVP--------ILADEDV 256
+L GKK + P+++ + +L D V
Sbjct: 259 LLILMEARLSALYKLESDYEILERFPGAYLKGKKYR-PLFDYFLKCKENGAFTVLVDNYV 317
Query: 257 DPNFGTGAVYNCTYGDEQDIVWQKRYN------LPVIIAINEDGTMNENAGPYAGLKVEE 310
GTG V+ Y +D +N LPV ++ G +AG V++
Sbjct: 318 KEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVC-PVDASGCFTTEVTDFAGQYVKD 376
Query: 311 ARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKV 370
A K I L++ G L H RS + +P WF+RV++ D++++
Sbjct: 377 ADKSIIRTLKEQGRLLVATTFTHSY-PFCWRSDTPLIYKAVPS--WFVRVENMVDQLLRN 433
Query: 371 AKEINWYPEDMF-LRLKDWAESMDWDWVISRQRVFGTPFPFWVCKN-------GHIIPAR 422
W PE + R +W + DW ISR R +GTP P WV + G +
Sbjct: 434 NDLCYWVPELVREKRFGNWLKDAR-DWTISRNRYWGTPIPLWVSDDFEEVVCIGSVAELE 492
Query: 423 EEDLPVDPRFDKPPVEKCPV---CG-AEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDE 478
E + V+ + CG + +++V DCW +S P + +
Sbjct: 493 ELSGAKISDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMP------YAQVHYPF 546
Query: 479 EAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMS 538
E K+ FE FP +G D R W + + L G+ P+K++++NG+V DG+KMS
Sbjct: 547 ENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMS 606
Query: 539 KSYGNVVAPDEVIPKYGADALRLWTALAP--PGEDHPFKWETVDYNFRFLQKVW-NIYRF 595
K N P +I KYGADALRL+ +P E+ FK E V + + W N YRF
Sbjct: 607 KRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAYRF 666
Query: 596 AERHIKDFDYEKYKDIEL-----------EPLDRWILSRLHRIIKFATEELERYRFNLIT 644
+++ +K ++IE DRWILS + +I F E+ YR +
Sbjct: 667 LIQNV--LRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEMAAYRLYTVV 724
Query: 645 RELMTFIWHEVADDYIEMVKYRLYGDD-EESKLKAKVALYELLYNVMLLLAPFVPHITEE 703
L+ F+ + + Y+ M + RL G++ E + A L+ +L ++ L+AP+ P +TE
Sbjct: 725 PRLVKFV-DILTNWYVRMNRRRLKGENGMEDCVMALETLFSVLLSLCRLMAPYTPFLTEL 783
Query: 704 IYHAM--------FKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNS 755
+Y + +DK S+H L P RE+ ID+K E + V+ R ++
Sbjct: 784 MYQNLKVLIDPVSVQDK-DTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDR 842
Query: 756 HGMPLNAKLEHVAIYAL--ESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPN 813
+P+ L+ + + E+ D+K +EK I +N+ K+ + + + R+ +P+
Sbjct: 843 KTIPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRL-RAEPD 901
Query: 814 YKRIGPRYGKLVPRIVEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVMI 867
+ +G R ++ +K + + ++ G + ++G EL ED+ +
Sbjct: 902 HMVLGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTI--VVEGH--ELHDEDIRL 951
>gi|11429023 isoleucine-tRNA synthetase [Homo sapiens]
Length = 1262
Score = 269 bits (680), Expect = 1e-70
Identities = 242/954 (25%), Positives = 414/954 (43%), Gaps = 119/954 (12%)
Query: 12 EPKWQKYWLEEKIYKYRLDENK--PSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRM 69
E K ++W E ++ L ++K P + PPF +G H GH+L+ T DI+ RY
Sbjct: 15 EEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQ 74
Query: 70 RGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCVEWTWQAIEAMRKQ 123
G++V G+D HGLP E +++K GI + E+ +C + +
Sbjct: 75 SGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQCRAIVMRYSAEWKST 134
Query: 124 FIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV 183
R+G D+D +Y T+ + +V + Y KGL+YR + + C T L+ E
Sbjct: 135 VSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFES 194
Query: 184 --GYVEEEGYLYYIKLPLADGSGYIPIA-TTRPELMPACVAVFVHPDDERYK-------- 232
Y + + ++ PL + +A TT P +P+ +AV V+P+ + K
Sbjct: 195 HQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGR 254
Query: 233 ----------------------------HLVGKKVKLPIYEREVP--------ILADEDV 256
+L GKK + P+++ + +L D V
Sbjct: 255 LLILMEARLSALYKLESDYEILERFPGAYLKGKKYR-PLFDYFLKCKENGAFTVLVDNYV 313
Query: 257 DPNFGTGAVYNCTYGDEQDIVWQKRYN------LPVIIAINEDGTMNENAGPYAGLKVEE 310
GTG V+ Y +D +N LPV ++ G +AG V++
Sbjct: 314 KEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVC-PVDASGCFTTEVTDFAGQYVKD 372
Query: 311 ARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKV 370
A K I L++ G L H RS + +P WF+RV++ D++++
Sbjct: 373 ADKSIIRTLKEQGRLLVATTFTHSY-PFCWRSDTPLIYKAVPS--WFVRVENMVDQLLRN 429
Query: 371 AKEINWYPEDMF-LRLKDWAESMDWDWVISRQRVFGTPFPFWVCKN-------GHIIPAR 422
W PE + R +W + DW ISR R +GTP P WV + G +
Sbjct: 430 NDLCYWVPELVREKRFGNWLKDAR-DWTISRNRYWGTPIPLWVSDDFEEVVCIGSVAELE 488
Query: 423 EEDLPVDPRFDKPPVEKCPV---CG-AEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDE 478
E + V+ + CG + +++V DCW +S P + +
Sbjct: 489 ELSGAKISDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMP------YAQVHYPF 542
Query: 479 EAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMS 538
E K+ FE FP +G D R W + + L G+ P+K++++NG+V DG+KMS
Sbjct: 543 ENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMS 602
Query: 539 KSYGNVVAPDEVIPKYGADALRLWTALAP--PGEDHPFKWETVDYNFRFLQKVW-NIYRF 595
K N P +I KYGADALRL+ +P E+ FK E V + + W N YRF
Sbjct: 603 KRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAYRF 662
Query: 596 AERHIKDFDYEKYKDIEL-----------EPLDRWILSRLHRIIKFATEELERYRFNLIT 644
+++ +K ++IE DRWILS + +I F E+ YR +
Sbjct: 663 LIQNV--LRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEMAAYRLYTVV 720
Query: 645 RELMTFIWHEVADDYIEMVKYRLYGDD-EESKLKAKVALYELLYNVMLLLAPFVPHITEE 703
L+ F+ + + Y+ M + RL G++ E + A L+ +L ++ L+AP+ P +TE
Sbjct: 721 PRLVKFV-DILTNWYVRMNRRRLKGENGMEDCVMALETLFSVLLSLCRLMAPYTPFLTEL 779
Query: 704 IYHAM--------FKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNS 755
+Y + +DK S+H L P RE+ ID+K E + V+ R ++
Sbjct: 780 MYQNLKVLIDPVSVQDK-DTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDR 838
Query: 756 HGMPLNAKLEHVAIYAL--ESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPN 813
+P+ L+ + + E+ D+K +EK I +N+ K+ + + + R+ +P+
Sbjct: 839 KTIPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRL-RAEPD 897
Query: 814 YKRIGPRYGKLVPRIVEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVMI 867
+ +G R ++ +K + + ++ G + ++G EL ED+ +
Sbjct: 898 HMVLGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTI--VVEGH--ELHDEDIRL 947
>gi|4504555 isoleucine-tRNA synthetase [Homo sapiens]
>gi|7770072|ref|NP_038203.1| isoleucine-tRNA synthetase
[Homo sapiens] >gi|440799|gb|AAA80153.1| (U04953)
isoleucyl-tRNA synthetase [Homo sapiens]
Length = 1262
Score = 269 bits (680), Expect = 1e-70
Identities = 242/954 (25%), Positives = 414/954 (43%), Gaps = 119/954 (12%)
Query: 12 EPKWQKYWLEEKIYKYRLDENK--PSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRM 69
E K ++W E ++ L ++K P + PPF +G H GH+L+ T DI+ RY
Sbjct: 15 EEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQ 74
Query: 70 RGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCVEWTWQAIEAMRKQ 123
G++V G+D HGLP E +++K GI + E+ +C + +
Sbjct: 75 SGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQCRAIVMRYSAEWKST 134
Query: 124 FIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV 183
R+G D+D +Y T+ + +V + Y KGL+YR + + C T L+ E
Sbjct: 135 VSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFES 194
Query: 184 --GYVEEEGYLYYIKLPLADGSGYIPIA-TTRPELMPACVAVFVHPDDERYK-------- 232
Y + + ++ PL + +A TT P +P+ +AV V+P+ + K
Sbjct: 195 HQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGR 254
Query: 233 ----------------------------HLVGKKVKLPIYEREVP--------ILADEDV 256
+L GKK + P+++ + +L D V
Sbjct: 255 LLILMEARLSALYKLESDYEILERFPGAYLKGKKYR-PLFDYFLKCKENGAFTVLVDNYV 313
Query: 257 DPNFGTGAVYNCTYGDEQDIVWQKRYN------LPVIIAINEDGTMNENAGPYAGLKVEE 310
GTG V+ Y +D +N LPV ++ G +AG V++
Sbjct: 314 KEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVC-PVDASGCFTTEVTDFAGQYVKD 372
Query: 311 ARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKV 370
A K I L++ G L H RS + +P WF+RV++ D++++
Sbjct: 373 ADKSIIRTLKEQGRLLVATTFTHSY-PFCWRSDTPLIYKAVPS--WFVRVENMVDQLLRN 429
Query: 371 AKEINWYPEDMF-LRLKDWAESMDWDWVISRQRVFGTPFPFWVCKN-------GHIIPAR 422
W PE + R +W + DW ISR R +GTP P WV + G +
Sbjct: 430 NDLCYWVPELVREKRFGNWLKDAR-DWTISRNRYWGTPIPLWVSDDFEEVVCIGSVAELE 488
Query: 423 EEDLPVDPRFDKPPVEKCPV---CG-AEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDE 478
E + V+ + CG + +++V DCW +S P + +
Sbjct: 489 ELSGAKISDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMP------YAQVHYPF 542
Query: 479 EAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMS 538
E K+ FE FP +G D R W + + L G+ P+K++++NG+V DG+KMS
Sbjct: 543 ENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMS 602
Query: 539 KSYGNVVAPDEVIPKYGADALRLWTALAP--PGEDHPFKWETVDYNFRFLQKVW-NIYRF 595
K N P +I KYGADALRL+ +P E+ FK E V + + W N YRF
Sbjct: 603 KRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAYRF 662
Query: 596 AERHIKDFDYEKYKDIEL-----------EPLDRWILSRLHRIIKFATEELERYRFNLIT 644
+++ +K ++IE DRWILS + +I F E+ YR +
Sbjct: 663 LIQNV--LRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEMAAYRLYTVV 720
Query: 645 RELMTFIWHEVADDYIEMVKYRLYGDD-EESKLKAKVALYELLYNVMLLLAPFVPHITEE 703
L+ F+ + + Y+ M + RL G++ E + A L+ +L ++ L+AP+ P +TE
Sbjct: 721 PRLVKFV-DILTNWYVRMNRRRLKGENGMEDCVMALETLFSVLLSLCRLIAPYTPFLTEL 779
Query: 704 IYHAM--------FKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNS 755
+Y + +DK S+H L P RE+ ID+K E + V+ R ++
Sbjct: 780 MYQNLKVLIDPVSVQDK-DTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDR 838
Query: 756 HGMPLNAKLEHVAIYAL--ESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPN 813
+P+ L+ + + E+ D+K +EK I +N+ K+ + + + R+ +P+
Sbjct: 839 KTIPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRL-RAEPD 897
Query: 814 YKRIGPRYGKLVPRIVEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVMI 867
+ +G R ++ +K + + ++ G + ++G EL ED+ +
Sbjct: 898 HMVLGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTI--VVEGH--ELHDEDIRL 947
>sp|P73505|SYI_SYNY3 ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437554|pir||S77211 isoleucine--tRNA ligase (EC
6.1.1.5) - Synechocystis sp. (strain PCC 6803)
>gi|1652625|dbj|BAA17545.1| (D90907) isoleucyl-tRNA
synthetase [Synechocystis sp.]
Length = 988
Score = 267 bits (676), Expect = 3e-70
Identities = 232/866 (26%), Positives = 366/866 (41%), Gaps = 113/866 (13%)
Query: 9 NEIEPKWQKYWLEEKIYKYRLDEN-KPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYK 67
N+ EP+ Q+YW E+ IY D N K + + PP+ +G LH+GH L+ DII +YK
Sbjct: 25 NKREPEIQQYWQEKGIYADLADNNPKDLFVLHDGPPYANGALHMGHALNKVLKDIINKYK 84
Query: 68 RMRGYNVLFPQGFDNHGLPTELKVEKEFGITKD---QPEEFLKKCVEWTWQAIEAMRKQF 124
++G+ V + G+D HGLP ELKV + ++ P K ++ +A + F
Sbjct: 85 LLQGHKVHYVPGWDCHGLPIELKVLQSLKSSERAELTPLTLRHKARDFALKAQQEQAVGF 144
Query: 125 IRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVG 184
R G DW Y T+ Y+AA KG IYR PV+W P RT+LA+AE+
Sbjct: 145 QRYGIWGDWKKPYLTLTPEYEAAQIGVFGAMALKGYIYRGLKPVHWSPSSRTALAEAELE 204
Query: 185 YVE-EEGYLYYIKLPLADGSG-------------YIPIATTRPELMPACVAVFVHPD--- 227
Y E Y+ P+ + I TT P +P +AV ++P+
Sbjct: 205 YPEGHTSRSIYVSFPITQAGEKAAEILAPYIDDLAVAIWTTTPWTLPGNLAVALNPELTY 264
Query: 228 ---------------------DERYKHLVGKKVKL----------------PIYEREVPI 250
E+ G K+ + P+++R PI
Sbjct: 265 AVVETESHIFHRSYLIVALDLVEKLSETFGVKLTVKVTLQGESLENTCYQHPLFDRVSPI 324
Query: 251 LADED-VDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKV- 308
+ D V GTG V+ ++D V +RY LP++ ++ G + E AG +AGL V
Sbjct: 325 VIGGDYVTTESGTGLVHTAPGHGQEDYVVGQRYGLPILSPVDAAGNLTEEAGKFAGLNVL 384
Query: 309 EEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIV 368
+A + I L+ +L K+E +H ++ P +QWF V+ F D+ +
Sbjct: 385 NDANEAIINALQDQKVLLKEEAYEH---KYPYDWRTKKPTIFRATEQWFASVEGFRDQAL 441
Query: 369 KVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKN------------- 415
K KE+ W P R+ DW ISRQR +G P P + +
Sbjct: 442 KAIKEVTWIPTQGENRITPMVGDRS-DWCISRQRAWGVPIPVFYDEETSEPLLTEETINH 500
Query: 416 -GHIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAI 474
II + D + ++ E G D +D W DS + W
Sbjct: 501 VQQIIAEKGSDAWWELTVEELLPEAYRNNGRTYRKGEDTMDVWFDSG------SSWAAVA 554
Query: 475 KGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDG 534
K +P + +G+D R W ++ + + G P+K ++ +G V G
Sbjct: 555 NAKNRPLK-----YPVDMYLEGSDQHRGWFQSSLLTSVAVNGIAPYKTVLTHGFVLDEKG 609
Query: 535 RKMSKSYGNVVAPDEVI---------PKYGADALRLWTALAPPGEDHPFKWETVDYNFRF 585
KMSKS GNVV P ++I P YGAD LRLW A D P +
Sbjct: 610 HKMSKSLGNVVDPYQIINGGKNQKQEPAYGADVLRLWVASVDYANDVPIGQGILKQLVDI 669
Query: 586 LQKVWNIYRFAERHIKDFDYE----KYKDIELEPLDRWILSRLHRIIKFATEELERYRFN 641
K+ N RF ++ DF+ E Y+D L LDR++L R+ + TE E ++F
Sbjct: 670 RNKIRNTARFLLGNLHDFNPETDAVAYED--LPELDRYMLHRMTEVFTEVTEAYESFQFF 727
Query: 642 LITRELMTFIWHEVADDYIEMVKYRLY--GDDEESKLKAKVALYELLYNVMLLLAPFVPH 699
+ + F ++++ Y+++ K RLY + + + L L N+ +AP + H
Sbjct: 728 KFFQTVQNFCVVDLSNFYLDIAKDRLYISAPNAPRRRSCQTILQLALENLTKAIAPVLCH 787
Query: 700 ITEEIYHAMFKDKIGEKSVHLLSW----PEYREDRIDEKAEKLGELARKV--VSEMRKYK 753
+ E+I+ + +K E SV W ++++ ++ +K L +L + + E +
Sbjct: 788 LAEDIWQFLPYEKPTE-SVFQSGWVNLDAQWQQPQLAQKWVSLRQLRDGINQLLEQARRD 846
Query: 754 NSHGMPLNAKLEHVAIYALESYDDLK 779
G L AKL V ES D K
Sbjct: 847 KVIGSSLEAKLIIVDPRTAESGTDEK 872
>pir||S17675 valine--tRNA ligase (EC 6.1.1.9) - human >gi|31545|emb|CAA41990.1|
(X59303) valyl-tRNA synthetase [Homo sapiens]
Length = 1265
Score = 265 bits (670), Expect = 2e-69
Identities = 237/844 (28%), Positives = 375/844 (44%), Gaps = 98/844 (11%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYA-------IDTPPPFTSGTLHLGHV 54
+P Y P +E W +W ++ +K S A + PPP +G+LHLGH
Sbjct: 296 MPDSYSPRYVEAAWYPWWEQQGFFKPEYGRPNVSAANPRGVFMMCIPPPNVTGSLHLGHA 355
Query: 55 LSHTWIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEK----EFGITKDQ--PEEFLKK 108
L++ D + R+ RMRG L+ G D+ G+ T++ VEK E G+++ Q E FL++
Sbjct: 356 LTNAIQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLWREQGLSRHQLGREAFLQE 415
Query: 109 CVEWTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPV 168
+W + + + Q ++G S DWD TMD AAV ++ + +++G+IYR V
Sbjct: 416 VWKWKEEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAAVTEAFVRLHEEGIIYRSTRLV 475
Query: 169 YWCPKCRTSLAKAEV--------------GYVE--EEGYL--YYIKLPLADGSGYIPIAT 210
W ++++ EV GY E E G L + K+ +D + +AT
Sbjct: 476 NWSCTLNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGVLVSFAYKVQGSDSDEEVVVAT 535
Query: 211 TRPELMPACVAVFVHPDDERYKHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTY 270
TR E M VAV VHP D RY+HL GK V P R +PI+ DE VD +FGTGA
Sbjct: 536 TRIETMLGDVAVAVHPKDTRYQHLKGKNVIHPFLSRSLPIVFDEFVDMDFGTGAGKITPA 595
Query: 271 GDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAG-LKVEEARKKIAEDLEKMGLLYKKE 329
D+ D +R+ L I ++ G ++ A + G +V K+ L++ G L++
Sbjct: 596 HDQNDYEVGQRHGLEAISIMDSRGGPHQCASAFPGPAQVLRPGKRCLVALKERG-LFRGI 654
Query: 330 KIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTD--EIVKVAKEINWYPEDMFLRLKD 387
+ V+ RS + +E L + QW++R + ++ PE
Sbjct: 655 EDNPMVVPLCNRSKDV--VEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRTWHA 712
Query: 388 WAESMDWDWVISRQRVFGTPFP-FWVCKNGHIIPAREED---LPVDPRFDKPPVEK-CPV 442
W +++ +W ISRQ +G P ++V + +P E+ V R + EK
Sbjct: 713 WMDNIR-EWCISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGRNEAEAREKAAKE 771
Query: 443 CGAEIEPVT-----DVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGT 497
G + ++ DVLD W S + PL I W E F +P L G
Sbjct: 772 FGVSPDKISLQQDEDVLDTWFFSGLFPLSILGW----PNQSEDLSVF---YPGTLLETGH 824
Query: 498 DIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEV------- 550
DI+ W + KLTG+ P++++ ++ +V GRKMSKS GNV+ P +V
Sbjct: 825 DILFFWVARMVMLGLKLTGRLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIYGISLQ 884
Query: 551 ------------------------------IPKYGADALRL-WTALAPPGEDHPFKWETV 579
IP+ G DALR A G D +
Sbjct: 885 GLHNQLLNSNLDPSEVEKAKEGQKADFPAGIPECGTDALRFGLCAYMSQGRDINLDVNRI 944
Query: 580 DYNFRFLQKVWNIYRFAERHI-KDF--DYEKYKDIELEPLDRWILSRLHRIIKFATEELE 636
F K+WN +FA R + K F +DRWI SRL ++ + + +
Sbjct: 945 LGYRHFCNKLWNATKFALRGLGKGFVPSPTSQPGGHESLVDRWIRSRLTEAVRLSNQGFQ 1004
Query: 637 RYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPF 696
Y F +T +F +E+ D Y+E +K L G D+ + A+ LY L + LL+PF
Sbjct: 1005 AYDFPAVTTAQYSFWLYELCDVYLECLKPVLNGVDQVAAECARQTLYTCLDVGLRLLSPF 1064
Query: 697 VPHITEEIYHAM-FKDKIGEKSVHLLSWPEYRE-DRIDEKAEKLGELARKVVSEMRKYKN 754
+P +TEE++ + + S+ + +PE E D +AE ELA + +R +
Sbjct: 1065 MPFVTEELFQRLPRRMPQAPPSLCVTPYPEPSECSWKDPEAEAALELALSITRAVRSLRA 1124
Query: 755 SHGM 758
+ +
Sbjct: 1125 DYNL 1128
>emb|CAC12008.1| (AL445065) isoleucyl-tRNA synthetase related protein [Thermoplasma
acidophilum]
Length = 1014
Score = 262 bits (663), Expect = 1e-68
Identities = 237/931 (25%), Positives = 414/931 (44%), Gaps = 111/931 (11%)
Query: 10 EIEPKWQKYWLEEKIYKYRLDEN-KPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKR 68
EI+ + KYW ++ I + L + + PP +G H+GH ++ T DI+ RY
Sbjct: 5 EIDSEILKYWKDKNILEKILSKGGSKKFVFLEGPPTANGRPHIGHAMTRTIKDIVLRYNT 64
Query: 69 MRGYNVLFPQG-FDNHGLPTELKVEKEFGI-TKDQ-----PEEFLKKCVEWTWQAIEAMR 121
M + + G +D HGLP EL+ EK FG TK + E+F + C E ++ I+ +
Sbjct: 65 MTDHKIYRRVGGWDCHGLPVELEAEKHFGFHTKSEIVNFGVEKFNQYCRESIFRYIDEWK 124
Query: 122 KQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKA 181
+ IG+S D + +Y T+ + Y + +L Y GL+Y++ V +CP+C TSL+
Sbjct: 125 QVDDLIGFSIDHNGDYITLRNDYMESEWFALKTMYNSGLLYKDYTVVPYCPRCETSLSSH 184
Query: 182 EV--GYVEEEGYLYYIKLPLADGSG-YIPIATTRPELMPACVAVFVHPDDE--------- 229
EV GY + + Y++ AD Y TT P +P+ + V+PD E
Sbjct: 185 EVAQGYKDVKDPSVYVRFKSADEENTYFVAWTTTPWTLPSNEFLVVNPDMEYSLVEAQGS 244
Query: 230 RY----------------------KHLVGKKVK--LPIYER---EVPILADEDVDPNFGT 262
RY + LVGK+ +P + + ++A V G+
Sbjct: 245 RYYVASSRAGYIFKEYREIRRMHGRDLVGKRYLQLMPFLDPPSGSLKVVAGSFVTSEDGS 304
Query: 263 GAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKM 322
G V+ D K + ++ ++++G + P+ G V +A + I L+K
Sbjct: 305 GIVHAAPAFGADDYQIGKEEGVEILNPVDKNGRFADPRIPWNGKFVRDANEDIIVYLKKN 364
Query: 323 GLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDMF 382
+L K EK +H + C P+ P WFI V D++V+ + INW P+ +
Sbjct: 365 QMLLKSEKYEHS---YPFCYRCDTPLLYYPLDAWFIAVSRIRDKLVEYNERINWKPD--Y 419
Query: 383 LRLKDWAESMDW--DWVISRQRVFGTPFPFWVCKNGHII----PAREEDL--PVDPRFDK 434
L+ + + DW +SR R +GTP P W CKNGH++ EDL V +
Sbjct: 420 LKHGRFGNFLGEAKDWNLSRDRFWGTPLPAWRCKNGHLVFVGSRKEIEDLGGKVPEDLHR 479
Query: 435 PPVE----KCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPT 490
P ++ KCP CG E+ V+D W DS + + D E + P
Sbjct: 480 PYIDEVRFKCPTCGEEMSREPYVIDTWFDSGSATYAASHYPFEKNFDPET------DVPV 533
Query: 491 ALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEV 550
+ + D R W + + K ++ + + GRKMSKS GN V +
Sbjct: 534 SFITEAIDQTRGWFYVLHVIATIMFNKNAYESALSINFILDAQGRKMSKSKGNSVYALDF 593
Query: 551 IPKYGADALRLWTALAPPGEDHPFKWETVD-YNFRFLQKVWNIYRFAERHIKDFDYEKYK 609
+ + D+LRL+ P + + +D + + L V N+Y F + + D ++
Sbjct: 594 LNEVPPDSLRLFFLYGAPWKSKNLDKKVIDEVSRKTLMTVLNVYSFF-AYNANIDNFQWN 652
Query: 610 DIEL--EPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRL 667
++L LDR+++S+++ ++ + + E F+ + R M F+ ++++ Y+ + + R
Sbjct: 653 GLQLSGNALDRYMVSKVNSFVRSSRDAYESLDFHEVVRASMEFV-DDLSNFYLRLSRRRF 711
Query: 668 YGDD-EESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEY 726
+ + ++ KL A LY L ++AP P ++ IY + DK +SVHL ++PE+
Sbjct: 712 WAEGFDDDKLSAYSTLYYALKAFSEVMAPITPFFSDFIYLNLGGDK---ESVHLEAFPEF 768
Query: 727 REDRIDEKAEKLGELARKVVSEMRKYKNSHGM----PLN-----AKLEHVAIYALES--- 774
+DEK E + A V+ +R+ + + + PL +E I ++S
Sbjct: 769 DSTLMDEKLESEMDRAYSVIETVRRLRQENSIKGRQPLREILIAGDMEESIIDVVKSELN 828
Query: 775 YDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKN 834
D+KLIE+D L + + P L R+ V+ + +
Sbjct: 829 AKDIKLIERDQEPIRLSADLRMDRAAPVLRSRVNAVRHKIRSM----------------- 871
Query: 835 NAESIAREIKENGKVEFE---IDGEKVELTK 862
+ + R+I E G VE + +D + VE+++
Sbjct: 872 DGLEVQRQISEKGFVEIDGVRLDPDMVEISR 902
>dbj|BAB10327.1| (AB017061) isoleucyl-tRNA synthetase [Arabidopsis thaliana]
Length = 988
Score = 261 bits (659), Expect = 3e-68
Identities = 229/854 (26%), Positives = 370/854 (42%), Gaps = 121/854 (14%)
Query: 12 EPKWQKYWLEEKIYKYRLDENKP-SYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRMR 70
EP+ QK W E +++K D N S+ + PP+ +G LH+GH L+ DII RYK ++
Sbjct: 38 EPELQKLWEENQVFKRVSDNNNGGSFILHDGPPYANGDLHMGHALNKILKDIINRYKLLQ 97
Query: 71 GYNVLFPQGFDNHGLPTELKVEKEFG--ITKD-QPEEFLKKCVEWTWQAIEAMRKQFIRI 127
Y V + G+D HGLP ELKV + + K+ P + K ++ ++ + F R
Sbjct: 98 NYKVQYVPGWDCHGLPIELKVLQSLDQEVRKELTPLKLRAKAAKFAKATVKTQMESFKRF 157
Query: 128 GYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVGYVE 187
G ADW+ Y T+D Y+AA + + KG IYR PV+W P RT+LA+AE+ Y
Sbjct: 158 GVWADWNNPYLTLDPEYEAAQIEVFGQMALKGYIYRGRKPVHWSPSSRTALAEAELEY-- 215
Query: 188 EEGYL---YYIKLPLADGSG-----------YIPIATTRPELMPACVAVFVHP------- 226
EG++ Y L G+ Y+ + TT P MPA AV V+
Sbjct: 216 PEGHISKSIYAIFKLVGGAKTSLLDEFIPNIYLAVWTTTPWTMPANAAVAVNAKLQYSVV 275
Query: 227 -----DDERYKHLV------------GKKVKL----------------PIYEREVPILAD 253
+ ++ +V G K+ + PI R+ P++
Sbjct: 276 EVQSFNQQKLFVIVATDLVPALEAKWGVKLSISKTFLGSDLENCRYTHPIDNRDCPVVIG 335
Query: 254 ED-VDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKV-EEA 311
D + GTG V+ ++D +Y LP++ ++++G E AG + GL V E
Sbjct: 336 GDYITTESGTGLVHTAPGHGQEDYATGLKYGLPLVSPVDDEGKFTEEAGQFRGLSVLGEG 395
Query: 312 RKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVA 371
+ L++ L +E H ++ P +QWF V+ F +
Sbjct: 396 NTAVVSYLDENMSLVMEESYAH---KYPYDWRTKKPTIFRATEQWFASVEGFRTATMDAI 452
Query: 372 KEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFP-FWVCKNGH------------- 417
+ W P R+ S DW ISRQR +G P P F+ K
Sbjct: 453 NNVKWVPHQAVNRISAMTSSRS-DWCISRQRTWGVPIPAFYHVKTKEPLMNEETINHVKS 511
Query: 418 IIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGD 477
II + D + EK A+ E TD +D W DS + W + G
Sbjct: 512 IISQKGSDAWWYMSVEDLLPEKYRDKAADYEKGTDTMDVWFDSG------SSW-AGVLGK 564
Query: 478 EEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKM 537
E +FP + +GTD R W ++ + GK P+ ++ +G V G KM
Sbjct: 565 REGL-----SFPADVYLEGTDQHRGWFQSSLLTSIATQGKAPYSAVITHGFVLDEKGMKM 619
Query: 538 SKSYGNVVAPDEVI---------PKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQK 588
SKS GNVV P VI P YGAD +RLW + D + + +K
Sbjct: 620 SKSLGNVVDPRLVIEGGKNSKDAPAYGADVMRLWVSSVDYTGDVLIGPQILRQMSDIYRK 679
Query: 589 VWNIYRFAERHIKDFDYEK---YKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITR 645
+ R+ ++ D+ + Y+D+ + +D+ L +L ++K E E Y+F I +
Sbjct: 680 LRGTLRYLLGNLHDWRVDNAVPYQDLPI--IDQHALFQLENVVKNIQECYENYQFFKIFQ 737
Query: 646 ELMTFIWHEVADDYIEMVKYRLY--GDDEESKLKAKVALYELLYNVMLLLAPFVPHITEE 703
+ F ++++ Y ++ K RLY G ++ + L L +++ ++AP VPH+ E+
Sbjct: 738 IIQRFTIVDLSNFYFDIAKDRLYTGGTSSFTRRSCQTVLSTHLLSILRVIAPIVPHLAED 797
Query: 704 IYHAM---FKDKIGEKS--VHLLSWPEYREDRIDEKAE------KLGELARKV--VSEMR 750
++ + ++++ G + V L WP E + AE +L EL +V V E+
Sbjct: 798 VWQNLPFEYRNEDGSAAEFVFELKWPTLNEQWLSFPAEDVLFWQRLLELRTEVNKVLELA 857
Query: 751 KYKNSHGMPLNAKL 764
+ + G L AK+
Sbjct: 858 RNEKMIGSSLEAKV 871
>dbj|BAA95147.1| (D28500) mitochondrial isoleucine tRNA synthetase [Homo sapiens]
Length = 993
Score = 259 bits (655), Expect = 1e-67
Identities = 222/796 (27%), Positives = 339/796 (41%), Gaps = 115/796 (14%)
Query: 1 MLPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWI 60
+L ++ E+E + QK E R + K + + PP+ +G H+GH L+
Sbjct: 56 LLGRQQPDTELEIQ-QKCGFSELYSWQRERKVKTEFCLHDGPPYANGDPHVGHALNKILK 114
Query: 61 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPE--EFLKKCVEWTWQAIE 118
DI R+ M G + F G+D HGLP E+KV E G E KK + AIE
Sbjct: 115 DIANRFHMMNGSKIHFVPGWDCHGLPIEIKVLSELGREAQNLSAMEIRKKARSFAKAAIE 174
Query: 119 AMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSL 178
+ FIR G ADW+ Y+T D Y+A ++ + Y KGL+YR PV+W P RT+L
Sbjct: 175 KQKSAFIRWGIMADWNNCYYTFDGKYEAKQLRTFYQMYDKGLVYRSYKPVFWSPSSRTAL 234
Query: 179 AKAEVGYVEEE-GYLYYIKLPLA----------DGSGYIPIA--TTRPELMPACVAVFVH 225
A+AE+ Y E Y+K PL DGS + I TT+P +PA AV
Sbjct: 235 AEAELEYNPEHVSRSIYVKFPLLKPSPKLASLIDGSSPVSILVWTTQPWTIPANEAVCYM 294
Query: 226 PDDERYKHLVGKKVKLPIY--------------------------------------ERE 247
P+ + K L + ++
Sbjct: 295 PESKYAVVKCSKSGDLYVLAADKVASVASTLETTFETISTLSGVDLENGTCSHPLIPDKA 354
Query: 248 VPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLK 307
P+L V GTG V+ +D ++NLP+ ++EDG + AGP K
Sbjct: 355 SPLLPANHVTMAKGTGLVHTAPAHGMEDYGVASQHNLPMDCLVDEDGVFTDVAGPELQNK 414
Query: 308 --VEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTD 365
+EE + + L+ L K+EK+ H P+ + KQWFI + D
Sbjct: 415 AVLEEGTDVVIKMLQTAKNLLKEEKLVHSYPYDWRTKK---PVVIRASKQWFINITDIKT 471
Query: 366 EIVKVAKEINWYPEDMFLRLKDWAESMDWD--WVISRQRVFGTPFPFWVCKNG------- 416
++ K++ + P L E MD W ISRQRV+G P P + K
Sbjct: 472 AAKELLKKVKFIPGSA---LNGMVEMMDRRPYWCISRQRVWGVPIPVFHHKTKDEYLINS 528
Query: 417 ----HIIPAREEDLPVDPRFDKPPVEKCP------VCGA---EIEPVTDVLDCWVDSSIT 463
HI+ E+ D + PP + P V G E P D+LD W DS
Sbjct: 529 QTTEHIVKLVEQH-GSDIWWTLPPEQLLPKEVLSEVGGPDALEYVPGQDILDIWFDSG-- 585
Query: 464 PLIITRWHEAIKG-DEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKD 522
T W + G D+ A + E G D + W ++ + + P+K
Sbjct: 586 ----TSWSYVLPGPDQRADLYLE----------GKDQLGGWFQSSLLTSVAARKRAPYKT 631
Query: 523 IVINGMVAGPDGRKMSKSYGNVVAPDEVI---------PKYGADALRLWTALAPPGEDHP 573
++++G G G KMSKS GNV+ PD V+ P YGAD LR W A + +
Sbjct: 632 VIVHGFTLGEKGEKMSKSLGNVIHPDVVVNGGQDQSKEPPYGADVLRWWVADSNVFTEVA 691
Query: 574 FKWETVDYNFRFLQKVWNIYRFAERHIKDFDYE--KYKDIELEPLDRWILSRLHRIIKFA 631
++ + K+ N RF ++ DF+ E ++ +D+++L L +
Sbjct: 692 IGPSVLNAARDDISKLRNTLRFLLGNVADFNPETDSIPVNDMYVIDQYMLHLLQDLANKI 751
Query: 632 TEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEE--SKLKAKVALYELLYNV 689
TE ++Y F + R L TF E+++ Y ++K RLY + E + + AL E+L +
Sbjct: 752 TELYKQYDFGKVVRLLRTFYTRELSNFYFSIIKDRLYCEKENDPKRRSCQTALVEILDVI 811
Query: 690 MLLLAPFVPHITEEIY 705
+ AP +PH+ EE++
Sbjct: 812 VRSFAPILPHLAEEVF 827
>gi|6319395 cytoplasmic isoleucyl-tRNA synthetase; Ils1p [Saccharomyces
cerevisiae] >gi|135134|sp|P09436|SYIC_YEAST
ISOLEUCYL-TRNA SYNTHETASE, CYTOPLASMIC (ISOLEUCINE--TRNA
LIGASE) (ILERS) >gi|68524|pir||SYBYI4 isoleucine--tRNA
ligase (EC 6.1.1.5) - yeast (Saccharomyces cerevisiae)
>gi|3820|emb|CAA30733.1| (X07886) ILSI (AA 1-1072)
[Saccharomyces cerevisiae] >gi|498991|emb|CAA56034.1|
(X79489) ILS1 protein [Saccharomyces cerevisiae]
>gi|536123|emb|CAA84898.1| (Z35838) ORF YBL076c
[Saccharomyces cerevisiae]
Length = 1072
Score = 257 bits (649), Expect = 5e-67
Identities = 247/936 (26%), Positives = 417/936 (44%), Gaps = 120/936 (12%)
Query: 29 LDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRMRGYNVLFPQGFDNHGLPTE 88
L ++KP ++ PPF +GT H GH+L+ T DI+ RY M G++V G+D HG+P E
Sbjct: 33 LTKDKPEFSFFDGPPFATGTPHYGHILASTIKDIVPRYATMTGHHVERRFGWDTHGVPIE 92
Query: 89 LKVEKEFGIT-KDQP-----EEFLKKCVEWTWQAIEAMRKQFIRIGYSADWDLEYHTMDD 142
++K+ GIT KD E + +C RK R+G D+D +Y TM
Sbjct: 93 HIIDKKLGITGKDDVFKYGLENYNNECRSIVMTYASDWRKTIGRLGRWIDFDNDYKTMYP 152
Query: 143 WYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLA--KAEVGYVEEEGYLYYIKLPLA 200
+ + + + ++KG +YR + + T L+ +A+ Y + I +
Sbjct: 153 SFMESTWWAFKQLHEKGQVYRGFKVMPYSTGLTTPLSNFEAQQNYKDVNDPAVTIGFNVI 212
Query: 201 DGSGYIPIA-TTRPELMPACVAVFVH------------------------------PDDE 229
+A TT P +P+ +++ V+ P +E
Sbjct: 213 GQEKTQLVAWTTTPWTLPSNLSLCVNADFEYVKIYDETRDRYFILLESLIKTLYKKPKNE 272
Query: 230 RYK--------HLVGKKVKLPIY--------EREVPILADEDVDPNFGTGAVYNC-TYGD 272
+YK LVG K + P++ E +++D+ V + GTG V+N +G+
Sbjct: 273 KYKIVEKIKGSDLVGLKYE-PLFPYFAEQFHETAFRVISDDYVTSDSGTGIVHNAPAFGE 331
Query: 273 EQDIVWQKRYNLP----VIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKK 328
E + K + + AI++ G ++ + G+ V++A K I + L G L
Sbjct: 332 EDNAACLKNGVISEDSVLPNAIDDLGRFTKDVPDFEGVYVKDADKLIIKYLTNTGNLLLA 391
Query: 329 EKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDMF-LRLKD 387
+I+H RS P+ WF+RVK+ +++ + +W P + R +
Sbjct: 392 SQIRHSY-PFCWRSD--TPLLYRSVPAWFVRVKNIVPQMLDSVMKSHWVPNTIKEKRFAN 448
Query: 388 WAESMDWDWVISRQRVFGTPFPFWVCKN-------GHIIPARE-------EDLPVDPRFD 433
W + DW +SR R +GTP P WV + G I E DL D D
Sbjct: 449 WIANAR-DWNVSRNRYWGTPIPLWVSDDFEEVVCVGSIKELEELTGVRNITDLHRDV-ID 506
Query: 434 KPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALR 493
K + G +++ + +V DCW +S P H + E+ F+ P
Sbjct: 507 KLTIPSKQGKG-DLKRIEEVFDCWFESGSMPY--ASQHYPFENTEK----FDERVPANFI 559
Query: 494 PQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPK 553
+G D R W + L G P+K+++++G+V DGRKMSKS N P V+ K
Sbjct: 560 SEGLDQTRGWFYTLAVLGTHLFGSVPYKNVIVSGIVLAADGRKMSKSLKNYPDPSIVLNK 619
Query: 554 YGADALRLWTALAP--PGEDHPFKWETV-DYNFRFLQKVWNIYRFAERHIK--------D 602
YGADALRL+ +P E FK E V + + L WN ++F + I D
Sbjct: 620 YGADALRLYLINSPVLKAESLKFKEEGVKEVVSKVLLPWWNSFKFLDGQIALLKKMSNID 679
Query: 603 FDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEM 662
F Y+ + +DRWIL+ + +++F EE+ +Y+ + +L+ FI E+ + YI
Sbjct: 680 FQYDDSVKSD-NVMDRWILASMQSLVQFIHEEMGQYKLYTVVPKLLNFI-DELTNWYIRF 737
Query: 663 VKYRLYGDD-EESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGE------ 715
+ RL G++ E LKA +L++ L+ + +APF P ++E IY K+ I E
Sbjct: 738 NRRRLKGENGVEDCLKALNSLFDALFTFVRAMAPFTPFLSESIY-LRLKEYIPEAVLAKY 796
Query: 716 ----KSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEH-VAIY 770
+SVH LS+P +++ DE E + V+ R + + L L+ V ++
Sbjct: 797 GKDGRSVHFLSYPVVKKEYFDEAIETAVSRMQSVIDLGRNIREKKTISLKTPLKTLVILH 856
Query: 771 ALESY-DDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIV 829
+ ESY D++ ++ I +N+ + I E + V ++ +G + K ++
Sbjct: 857 SDESYLKDVEALKNYIIEELNVRDVVITSDEAKYGVEYKAV-ADWPVLGKKLKKDAKKVK 915
Query: 830 EHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDV 865
+ L + RE E+GK+E +EL K D+
Sbjct: 916 DALPSVTSEQVREYLESGKLEV----AGIELVKGDL 947
>pir||C82559 isoleucyl-tRNA synthetase XF2418 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9107606|gb|AAF85217.1|AE004051_1
(AE004051) isoleucyl-tRNA synthetase [Xylella
fastidiosa]
Length = 943
Score = 256 bits (646), Expect = 1e-66
Identities = 210/797 (26%), Positives = 336/797 (41%), Gaps = 116/797 (14%)
Query: 3 PKKYDPNEIEPKWQKYWLEEKIYKYRLDENK--PSYAIDTPPPFTSGTLHLGHVLSHTWI 60
P + D + EP + W + Y K P + + PP+ +G +HLGH ++
Sbjct: 17 PMRGDLPKREPAILERWERDDFYAQLRAHAKGRPLFLLHDGPPYANGQIHLGHAVNKILK 76
Query: 61 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFG---ITKDQPEEFLKKCVEWTWQAI 117
DII + K + G++ + G+D HGLP E+ +EK++G +T D + F +KC E+ + I
Sbjct: 77 DIIIKSKHLDGFDAPYIPGWDCHGLPIEIAIEKKYGKVGVTLDAVQ-FRQKCREYAAEQI 135
Query: 118 EAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTS 177
+ R+ F R+G DWD Y T+D ++A ++L + KG + R PV+WC C ++
Sbjct: 136 QLQRRDFKRLGIIGDWDAPYKTLDFRFEADEIRALAKIVDKGHLIRGTKPVHWCFDCGSA 195
Query: 178 LAKAEVGYVEEEGYLYYIKLPLADGSGY---------------IPIATTRPELMPACVAV 222
LA+AE+ Y ++ + + P D S +PI TT P +PA +A+
Sbjct: 196 LAEAEIEYTDKTSPMVDVAYPALDPSALAAVFNATLPPDVQLAVPIWTTTPWTLPASLAI 255
Query: 223 FVHPDDE----------------------------RYK------HLVGKKVKL------- 241
V P + RY H K +
Sbjct: 256 SVGPTLDYVLVEGPTHSGQRRWLILAEALAAKALARYGIAELLIHGSAKGAAMEQHILAH 315
Query: 242 PIY-EREVPILADEDVDPNFGTGAVYNCT-YGDEQDIVWQK-----RYNLPVIIAINEDG 294
P Y +R +P+L V GTGAV+ +G E V+Q+ Y+ + ++ G
Sbjct: 316 PFYPDRTIPLLLGNHVSAEDGTGAVHTAPGHGQEDHQVFQQYGLLNHYSAAELNPVDARG 375
Query: 295 TMNENAGPY-----AGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIE 349
P+ AGL + +A I + L G+L ++ H H R PI
Sbjct: 376 VYLPTTPPFSELTLAGLHIWKANPLIVDALRLRGVLLAAAEMHHSY-PHCWRHK--TPIV 432
Query: 350 LLPKKQWFIRVKD--FTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTP 407
QWFI ++ +K + WYP+ R+ E+ DW ISRQR +G P
Sbjct: 433 FRATPQWFISMEQAALRSAALKAITHVTWYPQWGQARILSMIENRP-DWTISRQRTWGVP 491
Query: 408 FPFWVCKNGHI-----------IPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDC 456
P +V ++ + R E VD + E + E +TD+LD
Sbjct: 492 IPLFVHRHSGAPHPRSAALMRQVADRVEQQGVDIWYSLDQTELLGTEADQYEKITDILDV 551
Query: 457 WVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTG 516
W DS IT HEA+ + K P L +G D R W ++ +
Sbjct: 552 WFDSGIT-------HEAVLLERGLPK------PADLYLEGADQHRGWFQSSLLTGVAMDN 598
Query: 517 KKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKW 576
P+K + +G GRKMSKS GN + P ++I GAD LRLW A +
Sbjct: 599 AAPYKQCLTHGFTVDQHGRKMSKSLGNGIEPQDIIKTLGADILRLWIASTDYSNEMSLSQ 658
Query: 577 ETVDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIELEP------LDRWILSRLHRIIKF 630
E + +++ N RF ++ FD + L P LDRWI+ R + +
Sbjct: 659 EILKRTTDAYRRIRNTARFLLGNLHGFD----PTLHLVPLSDMIALDRWIVHRAFELQQT 714
Query: 631 ATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLY--GDDEESKLKAKVALYELLYN 688
RY F I + ++ F ++ Y+++ K RLY +D + A+ A+Y L
Sbjct: 715 IKAAYTRYDFAEIVQTILNFCSVDLGSLYLDVTKDRLYTMREDAPGRRSAQTAMYHLTAA 774
Query: 689 VMLLLAPFVPHITEEIY 705
+ +AP + +E++
Sbjct: 775 FVRWIAPILSFTADELW 791
>sp|P57249|SYI_BUCAI ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|10038832|dbj|BAB12867.1| (AP001118) isoleucyl-tRNA
synthetase [Buchnera sp. APS]
Length = 940
Score = 254 bits (643), Expect = 2e-66
Identities = 199/776 (25%), Positives = 350/776 (44%), Gaps = 105/776 (13%)
Query: 12 EPKWQKYWLEEKIYKY--RLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRM 69
EP K W E +YK + ++ K + + PP+ +G +H+GH ++ DII + K M
Sbjct: 25 EPNILKSWNENNLYKLIRKKNQEKKIFFLHDGPPYANGNIHIGHAVNKILKDIIIKSKNM 84
Query: 70 RGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPE----EFLKKCVEWTWQAIEAMRKQFI 125
G++ + +D HGLP E KVE++ I +Q E EF +KC ++ +E +K FI
Sbjct: 85 SGFDAPYIPSWDCHGLPIEQKVEEK--IKSNQGEISTTEFQEKCRKYAQDQVEKQKKDFI 142
Query: 126 RIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVGY 185
R+G DWD + TM+ +A + K+L + +K +Y++ P++WC KC +SL++AE+ Y
Sbjct: 143 RLGVIGDWDNPHLTMNFKNEANIIKTLSKIVQKKHLYQDFKPIHWCLKCASSLSEAEIEY 202
Query: 186 VEEE------GYLYYIKLPLADGSGY---------IPIATTRPELMPACVAVFVHPDDER 230
+++ G+ + K + + + I TT P +P+ A+ +HPD +
Sbjct: 203 SKKKSDSIIVGFKFKYKSIIEKLFDFQISNKKEIHLLIWTTTPWTLPSSKAISIHPDFQY 262
Query: 231 Y------------KHLVGK-----KVKLPIYER--------------------EVPILAD 253
K LV K K+K I ++P++
Sbjct: 263 QLIETERCYLIIAKELVEKTLNTLKIKKSIIRNYVKGRFLEKMICLHPFLKNIDLPVILG 322
Query: 254 EDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENA-GPYAGLKVEEAR 312
+ V GTGAV+ +D + ++YN+ +N G N G+ V EA
Sbjct: 323 KHVTLESGTGAVHTAPDHGLEDYIISQKYNIKTSNIVNFKGEYISNTHDKLDGVNVLEAN 382
Query: 313 KKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRV--KDFTDEIVKV 370
I E L K + E + H S P+ QWFI + K ++++
Sbjct: 383 SIIIELLIKNNTFFHHESLIHSYPHCWRHKS---PVIYRATPQWFIDIDQKQLRIKLLQE 439
Query: 371 AKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVDP 430
K++ W PE R+ + + DW ISRQR +G P ++ KN I P
Sbjct: 440 IKKVRWIPEWGESRIGEMIKKRP-DWCISRQRKWGVPMSIFIHKNTRKIH------PNTF 492
Query: 431 RFDKPPVEKCPVCGAEI-----------------EPVTDVLDCWVDSSITPLIITRWHEA 473
F K +K + G ++ E + D+LD W +S T I
Sbjct: 493 VFMKKIAKKVELEGLQVWWNIDSKEILGEEYQSYEKILDILDVWFESGNTHTTI------ 546
Query: 474 IKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPD 533
+ + K + + N L +G+D R W ++ + ++ KKP+ +++ +G V
Sbjct: 547 ---NYKNKNYTKKNADMFL--EGSDQHRGWFMSSLIISTLISEKKPYSEVLTHGFVVDGK 601
Query: 534 GRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIY 593
G+KMSKS GN ++P+E++ GAD LRLW A + D E + + +++ N
Sbjct: 602 GQKMSKSIGNTISPNEIVDTLGADILRLWVASSNYSNDISISNEILKSSSDIYRRIRNTA 661
Query: 594 RFAERHIKDFDYEK--YKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFI 651
RF +I DFD +K + LD+W + + + + + Y F+ + + LM F
Sbjct: 662 RFMLANISDFDPKKNIISKENMVLLDKWAIGQTKIVQEEIIQHYNNYNFHAVIQRLMYFC 721
Query: 652 WHEVADDYIEMVKYRLY--GDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIY 705
E+ Y++++K R Y + + ++ A+Y ++ +++ +AP + +EI+
Sbjct: 722 SIEMGSFYLDIIKDRQYTLKKHSQERRSSQTAIYYIINSLVRWIAPILSFTADEIW 777
>gb|AAD56932.1|AF180145_24 (AF180145) isoleucyl-tRNA synthetase [Zymomonas mobilis]
Length = 941
Score = 254 bits (643), Expect = 2e-66
Identities = 220/817 (26%), Positives = 358/817 (42%), Gaps = 113/817 (13%)
Query: 3 PKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPS--YAIDTPPPFTSGTLHLGHVLSHTWI 60
P K + EP+ W +E +Y+ ++ K + + + PP+ +G +H+GH L+
Sbjct: 27 PMKAGLAKKEPEILARWQKEDLYQQLREQRKGAERFILHDGPPYANGDIHIGHALNKILK 86
Query: 61 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEF-----GITKD-QPEEFLKKCVEWTW 114
DII R K + G +V + G+D HGLP E KVE++F + KD EF +KC ++
Sbjct: 87 DIIMRTKPLLGKDVPYIPGWDCHGLPIEWKVEEQFRKKKLNVDKDVNAVEFRQKCRKYAV 146
Query: 115 QAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKC 174
++ R++F R+G +WD Y TM+ +A + L+ F + G IYR PV W
Sbjct: 147 HWVDTQRQEFKRLGVLGEWDNPYLTMNFEAEAIISGELMRFSETGQIYRGAKPVLWSVVE 206
Query: 175 RTSLAKAEVGYVEEEGYLYYIKLPLADGS------GYIPIATTRPELMPACVAVFVHPD- 227
+T+LA+AEV Y + + + + D GY I TT P +PA A+ PD
Sbjct: 207 KTALAEAEVDYADVDSTTIDLAFKITDSKIPELVGGYAVIWTTTPWTIPANRALAYGPDI 266
Query: 228 -----DERYKHLV------------------------GKKVKL-------PIYER----- 246
D KH + GK +L P++E+
Sbjct: 267 DYVLVDLNGKHYLFAEALLEDSLKRIGHEGDAPVLWRGKGAELDGSIAQHPMFEKGGFFA 326
Query: 247 -EVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNEN------ 299
P L V GTG V+ E D + K +N+ + A+ +DG ++
Sbjct: 327 EPRPFLGGSHVTTEAGTGIVHMAPDYGEDDFLLCKAHNIDPVFAVEDDGRYRKDWLWMGG 386
Query: 300 AGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIR 359
G K+ A I DL ++G L + H H+ RS P QWFI
Sbjct: 387 EGLVISPKINAADGPICSDLREVGALLATS-VLHHSYPHSWRSKAKLIYRCTP--QWFIA 443
Query: 360 V-----------KDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPF 408
+ K + +K E++W+P R++ E DWVISRQR +G P
Sbjct: 444 LDRPVEKGAIAGKTLRETALKAIDEVSWFPAKGKNRIQTMVEGRP-DWVISRQRAWGVPI 502
Query: 409 PFWVCK-NGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEI-----------EPVTDVLDC 456
+V + +G + E + + F K + ++ EPV D+LD
Sbjct: 503 TLYVNRESGDYLRDPEVNARILAAFRKEGADAWFKANHQLFLGDKYRLEDYEPVNDILDV 562
Query: 457 WVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTG 516
W DS T + EA G+ + L +G+D R W ++ + G
Sbjct: 563 WFDSGSTHAFVV---EARYGEGTRAQ---------LYLEGSDQHRGWFQSSLLESCGSRG 610
Query: 517 KKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKW 576
P++ ++ +G GRKMSKS GNV+ P +VI + GAD LR+W A ED
Sbjct: 611 HAPYEAVLTHGFTLDGTGRKMSKSVGNVIDPLKVINESGADILRMWVASTDYNEDVRISK 670
Query: 577 ETVDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDI-ELEPLDRWILSRLHRIIKFATEEL 635
E + +K+ N +R+ ++ F E+ D+ +L L+++IL L + + E +
Sbjct: 671 EVLSGTSDGYRKLRNSFRYLLGALEGFSEEEKVDLADLPELEKYILHLLAELDQALHESV 730
Query: 636 ERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEES------KLKAKVALYELLYNV 689
+ FN R L F+ ++++ + ++ K RLY D E+ + +A + ++L++
Sbjct: 731 NGFAFNRYLRLLSDFVNNDLSAFFFDIRKDRLYCDVGEAAPQGTEERRAYRTVLDILFHA 790
Query: 690 ML-LLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPE 725
++ AP + EE++ F D SVHL WPE
Sbjct: 791 LVRYAAPILCFTAEEVWLHRFPD---AGSVHLSVWPE 824
>gb|AAF51821.1| (AE003597) CG11471 gene product [alt 1] [Drosophila melanogaster]
>gi|7296538|gb|AAF51822.1| (AE003597) CG11471 gene
product [alt 2] [Drosophila melanogaster]
>gi|7296539|gb|AAF51823.1| (AE003597) CG11471 gene
product [alt 3] [Drosophila melanogaster]
Length = 1081
Score = 254 bits (643), Expect = 2e-66
Identities = 240/969 (24%), Positives = 412/969 (41%), Gaps = 148/969 (15%)
Query: 8 PNEIEPKWQKYWLEEKIYKY--RLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIAR 65
P E E QK W E I++ +L + KP Y PPF +G H GH+L+ T DI+ R
Sbjct: 20 PAEEENVLQK-WRHENIFEKCSQLSKGKPKYTFYDGPPFATGLPHYGHILAGTIKDIVTR 78
Query: 66 YKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLK--------KCVEWTWQAI 117
Y +GY+V G+D HGLP E +++K I PE+ K +C + +
Sbjct: 79 YAYQQGYHVDRRFGWDCHGLPVEFEIDKLLNIKG--PEDVAKMGIAAYNAECRKIVMRYA 136
Query: 118 EAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTS 177
+ R+G D+ +Y T+ WY ++ + + KGL+Y+ + + C TS
Sbjct: 137 DEWENVVTRVGRWIDFKNDYKTLYPWYMESIWWIFKQLFDKGLVYQGVKVMPYSTACTTS 196
Query: 178 LAKAEVGYVEEEGY-------LYYIKLPLADGSGYIPIATTRPELMPACVAVFVHP---- 226
L+ E +E L + LP + + + TT P +P+ A VHP
Sbjct: 197 LSNFEANQNYKEVVDPCVVVALEAVSLP----NTFFLVWTTTPWTLPSNFACCVHPTMTY 252
Query: 227 ---------------------------DDERYKHLVGKKVKLPIYEREVP---------- 249
+ E + VGK +K Y+ P
Sbjct: 253 VKVRDVKSDRLFVLAESRLSYVYKSETEYEVKEKFVGKTLKDLHYKPLFPYFAKRGAEVK 312
Query: 250 ---ILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNL-----PVIIAINEDGTMNENAG 301
+L DE V + GTG V+N Y E D L V+ ++E G A
Sbjct: 313 AYRVLVDEYVTEDSGTGIVHNAPYFGEDDYRVCLAAGLITKSSEVLCPVDEAGRFTNEAS 372
Query: 302 PYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVK 361
+ G V+++ K+I L+ G L ++KH RS + +P WF+RV+
Sbjct: 373 DFEGQYVKDSDKQIMAALKARGNLVSSGQVKHSY-PFCWRSDTPLIYKAVPS--WFVRVE 429
Query: 362 DFTDEIVKVAKEINWYPEDMF-LRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNG---- 416
+ ++ + + W P+ + R +W + DW ISR R +GTP P W +G
Sbjct: 430 HMSKNLLDCSSQTYWVPDFVKEKRFGNWLKEAR-DWAISRNRYWGTPIPIWRSPSGDETV 488
Query: 417 ---------HIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLII 467
+ + EDL + D + + + V DCW +S P
Sbjct: 489 VIGSIKQLAELSGVQVEDLHRES-IDHIEIPSAVPGNPPLRRIAPVFDCWFESGSMPF-- 545
Query: 468 TRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVING 527
+ H + +++ F +NFP +G D R W + + + L K P+K+++ +G
Sbjct: 546 AQQHFPFENEKD----FMNNFPADFIAEGIDQTRGWFYTLLVISTALFNKAPFKNLIASG 601
Query: 528 MVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAP--PGEDHPFKWETVDYNFRF 585
+V DG+KMSK N P EV+ KYGADALRL+ +P E FK E V +
Sbjct: 602 LVLAADGQKMSKRKKNYPDPMEVVHKYGADALRLYLINSPVVRAESLRFKEEGVRDIIKD 661
Query: 586 LQKVW-NIYRF----------------------AERHIKDFDYEKYKDIELEPLDRWILS 622
+ W N YRF ERH+K+ D + +D WILS
Sbjct: 662 VFLPWYNAYRFLLQNIVRYEKEDLAGNGQYTYDRERHLKNMD-------KASVIDVWILS 714
Query: 623 RLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGD-DEESKLKAKVA 681
+++F E++ YR + L FI ++ + Y+ + + R+ G+ + +++
Sbjct: 715 FKESLLEFFATEMKMYRLYTVVPRLTKFI-DQLTNWYVRLNRRRIKGELGADQCIQSLDT 773
Query: 682 LYELLYNVMLLLAPFVPHITEEIYHAMFKDKIG-----EKSVHLLSWPEYREDRIDEKAE 736
LY++LY ++ ++APF P++TE I+ + + SVH P ++ I E
Sbjct: 774 LYDVLYTMVKMMAPFTPYLTEYIFQRLVLFQPAGTLEHADSVHYQMMPVSQKKFIRNDIE 833
Query: 737 KLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALES--YDDLKLIEKDIAGTMNIEKL 794
+ L + VV R ++ +P+ + + +S + +K ++ I +N+ KL
Sbjct: 834 RSVALMQSVVELGRVMRDRRTLPVKYPVSEIIAIHKDSQILEAIKTLQDFILSELNVRKL 893
Query: 795 EIFKGEPQLEERIVEVKPNYKRIGPRYG---KLVPRIVEHLKNNAESIAREIKENGKVEF 851
+ + + + +P++K +G R K V ++ L++ + I +++ + F
Sbjct: 894 TL-SSDKEKYGVTLRAEPDHKALGQRLKGNFKAVMAAIKALRD--DEIQKQVSQG---YF 947
Query: 852 EIDGEKVEL 860
+I +++EL
Sbjct: 948 DILDQRIEL 956
>pir||G82894 isoleucyl-tRNA synthetase UU410 [imported] - Ureaplasma urealyticum
>gi|6899398|gb|AAF30821.1|AE002138_8 (AE002138)
isoleucyl-tRNA synthetase [Ureaplasma urealyticum]
Length = 900
Score = 253 bits (640), Expect = 6e-66
Identities = 200/778 (25%), Positives = 348/778 (44%), Gaps = 87/778 (11%)
Query: 9 NEIEPKWQKYWLEEKIYKYRLDENKPS--YAIDTPPPFTSGTLHLGHVLSHTWIDIIARY 66
N EPK Q++W+E +IY+ L +NK + + PP+ +G +H+GH L+ D + Y
Sbjct: 22 NVKEPKIQQFWVEHQIYEKLLTKNKDKKPFILHDGPPYANGNIHIGHALNKILKDFVVSY 81
Query: 67 KRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMRKQFIR 126
M Y + G+D HGLP E+ + K+ ++ E ++C ++ + + +QF+R
Sbjct: 82 HNMNNYYSPYIPGWDTHGLPIEVALSKKIKLSNLSVNERREQCKKYALEQVNNQIQQFLR 141
Query: 127 IGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVGYV 186
+G +D+ Y T+D Y+ K KKG IY++ PV+W +T+LA++E+ Y
Sbjct: 142 LGMISDFKQRYLTLDHNYEIDQLKLFTYMLKKGFIYQDFKPVFWSWSSQTALAESEIEYA 201
Query: 187 EEEGYLYYIKLPLADGSGY-------IPIATTRPELMPACVAVFVHPD---------DER 230
+ + Y+K+ + D + + I TT P +PA +A+ +HP+ +E
Sbjct: 202 DRQSSAIYVKMKVVDHNDLFTDKPTSLVIWTTTPWTLPANLAIAIHPELVYSLIEYKNEN 261
Query: 231 Y---KHLVGKKVKL------------------------PIYEREVPILADEDVDPNFGTG 263
Y K LV VK PI ++ ++ DE V N GTG
Sbjct: 262 YIIAKPLVETFVKKVGFEDYKWIKDFKANTLEKIKYISPISKKHAFVIMDEYVSANDGTG 321
Query: 264 AVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNE--NAGPYAGLKVEEARKKIAEDLEK 321
V+N +D K+Y + ++ I++ G N N + E+A + I L
Sbjct: 322 LVHNAPAFGLEDYYACKKYGIETVVMIDQFGKYNALVNDLELENMFYEDANQVILNRLMN 381
Query: 322 MGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDM 381
LL E I H V H R+ P+ KQWF+ ++ I++ N
Sbjct: 382 EHLLIHHEVITHSV-AHDWRTK--KPVMYRATKQWFVSIEKILPNILQTLN--NDVKSTS 436
Query: 382 FLRLKDWAESM--DWDWVISRQRVFGTPFPFWVCKNGHIIPARE---------EDLPVDP 430
F ++ E + +W ISRQRV+G P P +N + I E + V+
Sbjct: 437 FRGIERMHEMIVNRKEWCISRQRVWGVPIPMIFDENHNAIMDHELVENIINVLNEKGVNA 496
Query: 431 RFDKP-----PVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFE 485
FD + + D++D W DS + I+ +
Sbjct: 497 WFDLDVNAFLTPKYLSMKNKTFYKEKDIMDVWFDSGSSYNILGH--------------YN 542
Query: 486 HNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVV 545
N+P + +G D R W ++ L + P+K +V +GMV +G KMSKS GNVV
Sbjct: 543 LNYPADVYLEGYDQYRGWFNSSLITGTILNNRAPYKYLVAHGMVLDGEGYKMSKSKGNVV 602
Query: 546 APDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWN-IYRFAERHIKDFD 604
P +V YGAD LRLW A + D E + N +++ N +++++ + DF+
Sbjct: 603 DPLDVCKIYGADVLRLWIANSDYQNDTRISEEILKQNAEIYRRIRNTLFKYSLSILNDFE 662
Query: 605 YEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVK 664
+ ++++L+ + + + E + + + + FI +++ Y E +K
Sbjct: 663 PSVDFSFNVRQEEQFVLNEFNELHIKVIKAYENFDYQTVVKLFNKFIL-DLSSWYFENIK 721
Query: 665 YRLY--GDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHL 720
+Y ++ + + + A+Y +L N ++ L P +PH TEE Y + KD ++S+ L
Sbjct: 722 DDMYCLAINDPIRKQIQSAVYWILKNSLIDLTPIIPHTTEEAY-SFLKDANKKESIRL 778
>sp|O83466|SYI_TREPA ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437562|pir||E71322 isoleucine--tRNA ligase (EC
6.1.1.5) (ileS) - syphilis spirochete
>gi|3322738|gb|AAC65439.1| (AE001222) isoleucyl-tRNA
synthetase (ileS) [Treponema pallidum]
Length = 1091
Score = 253 bits (639), Expect = 7e-66
Identities = 236/998 (23%), Positives = 415/998 (40%), Gaps = 142/998 (14%)
Query: 18 YWLEEKIYKYRLDENKP--SYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRMRGYNVL 75
+W E ++++ + + SY PPF +G H GH + T DII RY+ MRG V
Sbjct: 21 FWRERRVFEQSVAQRAQGKSYVFFDGPPFATGLPHFGHFVPSTIKDIIPRYQTMRGAYVP 80
Query: 76 FPQGFDNHGLPTELKVEKEFGITKDQPEE------FLKKCVEWTWQAIEAMRKQFIRIGY 129
G+D HGLP E +E+E + E F C + ++ ++ R+G
Sbjct: 81 RRFGWDCHGLPIEHLIEQELNLNSKSDVESYGVSAFNAACRSSVLRYVKEWQRTLTRLGR 140
Query: 130 SADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV---GYV 186
D+D +Y TMD Y +V + + +++ L+Y + +CP+C T+L+ E+ GY
Sbjct: 141 WVDFDNDYKTMDVCYMESVWWVVAQLWQRKLLYEGYKILPYCPRCATALSNHELNLGGYQ 200
Query: 187 EEEGYLYYIKLPLAD-----------------GSGYIPIAT------TRPELMPACVAV- 222
+ ++ GS +P T T P +P A+
Sbjct: 201 DVSDPAITVRFECTSVVPGSPAAREFCAAASWGSASLPAHTCFLAWTTTPWTLPCNAALA 260
Query: 223 -------------------------FVHPDDERYK--------HLVGKKVKLPIYEREV- 248
F +PD Y+ HL G + + P++ V
Sbjct: 261 LGPQILYVLIEANDEHYILARSRLEFYYPDSSAYRVVWEKRGEHLAGIRYR-PLFSYPVF 319
Query: 249 ------PILADED-----------VDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAIN 291
+ D + V GTG V+ E D K + + ++
Sbjct: 320 GQGPDPSVQGDSEEGLFCTRVADFVSTEDGTGVVHVAPAFGEDDYEVFKDAGISIQCPLD 379
Query: 292 EDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELL 351
+ Y GL V+ A K I ++K G L+++E+I H H R C +P+
Sbjct: 380 AECRFTAEVADYQGLFVKAADKAIIARVQKQGALFRREQISH-AYPHCWR--CASPLIYR 436
Query: 352 PKKQWFIRVKDFTDEIVKVAKEINWYPEDMFL-RLKDWAESMDWDWVISRQRVFGTPFPF 410
WF+ V+ D+++ I W P + R W DW ISR R +G P P
Sbjct: 437 AVHSWFVAVEKIKDKMLAANASICWQPSHIRDGRFGKWLVCAR-DWAISRDRYWGNPLPI 495
Query: 411 WVCKN-------GHIIPAREEDLPVDPRFDKPPVEKCPV---CGAEIEPVTDVLDCWVDS 460
W C + G E + K V+ + CG+ + V +VLDCW +S
Sbjct: 496 WRCVHCGATDCIGSRTQLYERSGMLLEDLHKHVVDMVTIPCACGSVMRRVPEVLDCWFES 555
Query: 461 SITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPW 520
P + D FE FP +G D R W + L + +
Sbjct: 556 GAMPYAQQHYPFEHATD------FERYFPAHFISEGLDQTRGWFYTLTILAVALFERPAF 609
Query: 521 KDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLW--TALAPPGEDHPFKWET 578
++ ++ G+V DG+KMSK+ N P+EV+ +YGADALRL+ + +D + E
Sbjct: 610 ENCIVTGLVLASDGKKMSKALRNYADPNEVMDRYGADALRLFLVRSAVVRADDLKYSDEG 669
Query: 579 V-DYNFRFLQKVWNIYRF--AERHIKDFDYEKYKDIE-------------LEPLDRWILS 622
V D + +WN Y F +I D ++ PLDRWILS
Sbjct: 670 VKDILKTVIIPLWNSYSFYVTYANIDGIDPPVCAKVDGMGQAVTRLATHLNNPLDRWILS 729
Query: 623 RLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGD-DEESKLKAKVA 681
++++ L+ Y + + +++++ ++ + YI + R + ++E K A
Sbjct: 730 LTEKLVQDIACALDAYDVSKVADPIVSYV-DQLNNWYIRRSRRRFWKSINDEDKRCAYNT 788
Query: 682 LYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGEL 741
LY +L +L +AP VP ITE I+ + + +SVHL +P D+ E E
Sbjct: 789 LYCVLKRCVLAIAPVVPFITESIWQNI-RAADDVQSVHLADYPVCTPMVRDDALEFKMET 847
Query: 742 ARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESYDDLKLI--EKDIAGTMNIEKLEIFKG 799
++VVS R + + + L+ + + + L+ E+D+ +N+++L +
Sbjct: 848 VQRVVSMARAIRAQCNLKVRQPLKAMQVITRNPMERSALLEMEEDVLDELNVKELVFHEK 907
Query: 800 EPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKNNAESIAREIKENGKVEFEIDGEKVE 859
E ++ E K N++ +G G R ++ + + +EI E + ++DG+++E
Sbjct: 908 EDEIVE--YRAKANFRVLGKELGSKTKRAALSIERLSSAEIQEILEGTTLYLDVDGDRLE 965
Query: 860 LTKEDVMIKK------EVFSEGE---RVETAVVDDIVI 888
LT+E +++++ + +EG ++T + +D+++
Sbjct: 966 LTEEKILVQRIERESLKAINEGTLTVALDTTLTEDLLL 1003
>sp|P00956|SYI_ECOLI ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7428465|pir||SYECIT isoleucine--tRNA ligase (EC
6.1.1.5) - Escherichia coli >gi|2367096|gb|AAC73137.1|
(AE000113) isoleucine tRNA synthetase [Escherichia coli
K12]
Length = 938
Score = 251 bits (635), Expect = 2e-65
Identities = 211/798 (26%), Positives = 345/798 (42%), Gaps = 95/798 (11%)
Query: 3 PKKYDPNEIEPKWQKYWLEEKIYKY--RLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWI 60
P + D + EP W ++ +Y + K ++ + PP+ +G++H+GH ++
Sbjct: 16 PMRGDLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGSIHIGHSVNKILK 75
Query: 61 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQ--PEEFLKKCVEWTWQAIE 118
DII + K + GY+ + G+D HGLP ELKVE+E+G ++ EF KC E+ ++
Sbjct: 76 DIIVKSKGLSGYDSPYVPGWDCHGLPIELKVEQEYGKPGEKFTAAEFRAKCREYAATQVD 135
Query: 119 AMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSL 178
RK FIR+G DW Y TMD +A + ++L + G +++ PV+WC CR++L
Sbjct: 136 GQRKDFIRLGVLGDWSHPYLTMDFKTEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSAL 195
Query: 179 AKAEVGY--------------VEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFV 224
A+AEV Y V+++ + +G + I TT P +PA A+ +
Sbjct: 196 AEAEVEYYDKTSPSIDVAFQAVDQDALKAKFAVSNVNGPISLVIWTTTPWTLPANRAISI 255
Query: 225 HPD-DERYKHLVGKKVKL-----------------------------------PIYEREV 248
PD D + G+ V L P +V
Sbjct: 256 APDFDYALVQIDGQAVILAKDLVESVMQRIGVTDYTILGTVKGAELELLRFTHPFMGFDV 315
Query: 249 PILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYA-GLK 307
P + + V + GTGAV+ D V ++Y L + DGT P G+
Sbjct: 316 PAILGDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVN 375
Query: 308 VEEARKKIAEDLEKMGLLYKKEKIKHRV---LRHTERSSCMAPIELLPKKQWFIRV--KD 362
V +A + L++ G L EK++H RH PI QWF+ + K
Sbjct: 376 VFKANDIVVALLQEKGALLHVEKMQHSYPCCWRHK------TPIIFRATPQWFVSMDQKG 429
Query: 363 FTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPAR 422
+ +K K + W P+ R++ + DW ISRQR +G P +V K+ + R
Sbjct: 430 LRAQSLKEIKGVQWIPDWGQARIESMVANRP-DWCISRQRTWGVPMSLFVHKDTEELHPR 488
Query: 423 EEDL--PVDPRFDKPPVEKC------PVCGAEIEP---VTDVLDCWVDSSITPLIITRWH 471
+L V R + ++ + G E + V D LD W DS T +
Sbjct: 489 TLELMEEVAKRVEVDGIQAWWDLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVVDVR 548
Query: 472 EAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAG 531
G A + E G+D R W ++ + + GK P++ ++ +G
Sbjct: 549 PEFAG-HAADMYLE----------GSDQHRGWFMSSLMISTAMKGKAPYRQVLTHGFTVD 597
Query: 532 PDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWN 591
GRKMSKS GN V+P +V+ K GAD LRLW A + E + +++ N
Sbjct: 598 GQGRKMSKSIGNTVSPQDVMNKLGADILRLWVASTDYTGEMAVSDEILKRAADSYRRIRN 657
Query: 592 IYRFAERHIKDFDYEK--YKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMT 649
RF ++ FD K K E+ LDRW + + + E Y F+ + + LM
Sbjct: 658 TARFLLANLNGFDPAKDMVKPEEMVVLDRWAVGCAKAAQEDILKAYEAYDFHEVVQRLMR 717
Query: 650 FIWHEVADDYIEMVKYRLY--GDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHA 707
F E+ Y++++K R Y D ++ + ALY + ++ +AP + +E++
Sbjct: 718 FCSVEMGSFYLDIIKDRQYTAKADSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGY 777
Query: 708 MFKDKIGEKSVHLLSWPE 725
+ ++ EK V W E
Sbjct: 778 LPGER--EKYVFTGEWYE 793
>sp|Q9WY15|SYL_THEMA LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437543|pir||F72408 leucine--tRNA ligase (EC
6.1.1.4) - Thermotoga maritima (strain MSB8)
>gi|4980663|gb|AAD35261.1|AE001702_1 (AE001702)
leucyl-tRNA synthetase [Thermotoga maritima]
Length = 824
Score = 251 bits (634), Expect = 3e-65
Identities = 234/847 (27%), Positives = 358/847 (41%), Gaps = 192/847 (22%)
Query: 4 KKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDII 63
K+Y P EIE KWQ+ W E+K++ KP Y P+ SGTLH+GHV ++ DI+
Sbjct: 2 KEYRPQEIEKKWQEVWEEKKVFYTPQRSEKPKYYALVMFPYPSGTLHVGHVKNYVIGDIV 61
Query: 64 ARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMRKQ 123
ARYKRMRGYNVL P G+D GLP E E GI PE EWT + I +R+Q
Sbjct: 62 ARYKRMRGYNVLHPFGYDAFGLPAE-NAAIEKGI---HPE-------EWTRKNIATIRQQ 110
Query: 124 FIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV 183
++G S DW E T D+ Y Q L+ YK GL Y+++ V WCPKC+T LA +V
Sbjct: 111 VKKLGISYDWSREIATCDEEYYKWTQWIFLQLYKNGLAYKKKAAVNWCPKCKTVLANEQV 170
Query: 184 -------------------------GYVEE--------EGYLYYIK-------------- 196
Y E G+ ++K
Sbjct: 171 KDGKCERCGTSVTIRHLEQWFFKITDYAERLLNDLDKLTGWPEHVKTMQRNWIGKSTGAE 230
Query: 197 --LPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVGKKVKLPIYE--------- 245
P+ I + TTRP+ + + + P+ + LV ++ K + E
Sbjct: 231 IDFPVEGSDTKIRVFTTRPDTLWGVTFMALAPESPLVEELVPEEKKEELQEFLERVKQQD 290
Query: 246 --REVPILADED--------VDP----------------NFGTGAVYNCTYGDEQDIVWQ 279
R + A+++ ++P +GTGA+ D++D +
Sbjct: 291 RFRRTSVEAEKEGFFLGRYAINPVTGERIPIYVANYILMEYGTGAIMGVPAHDQRDFSFA 350
Query: 280 KRYNLPVIIAIN---------------EDGTMNENAGPYAGLKVEEARKKIAEDLEKMGL 324
K+Y +P+ + I E + N+GP+ G E +K+ LE+ G+
Sbjct: 351 KKYGIPIKVVIKPADKDLDPEKMEEAYEGEGIMVNSGPFDGTPSSEGIEKVINWLEEKGI 410
Query: 325 LYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDMFLR 384
+ + K R + + API ++ ++ +V V + ED+ +R
Sbjct: 411 GKRSVQYKLRDWLISRQRYWGAPIPIIYCEKC---------GVVPVPE------EDLPVR 455
Query: 385 LKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVDPRFDKPPVEKCPVCG 444
L K+ +P + L F K KCPVCG
Sbjct: 456 LP---------------------------KDVEFLPTGQSPLSFHEGFKK---TKCPVCG 485
Query: 445 AEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDE--EAKKWFEHNFPTALRPQGTDIIRT 502
E + TD +D +VDSS L H K E + W P G +
Sbjct: 486 GEAQRETDTMDTFVDSSWYFLRYVNPHLEDKPFEPDDVNYW----LPVDQYIGGVEHAVL 541
Query: 503 WAFYTIFRT------FKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGA 556
Y+ F T L +P+ ++ GM+ DG KMSKS GNVV+PDE+I KYGA
Sbjct: 542 HLLYSRFVTKVLHDLGYLNFDEPFTNLFTQGMIY-KDGAKMSKSKGNVVSPDEMIEKYGA 600
Query: 557 DALRLWTA-LAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIELEP 615
D LR++ +APP +D + ++ RF++++WN + +K+ + E +
Sbjct: 601 DTLRMYILFMAPPEKDAEWSDAGIEGVHRFVKRLWNTFYTVLPFVKEENTENL--VLKNS 658
Query: 616 LDRWILSRLHRIIKFATEELE-RYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEES 674
++ + +LH IIK TE++E ++FN LM + H Y+ V EE
Sbjct: 659 TEKELRRKLHSIIKKITEDIEGGFKFNTAISGLMELVNH--LSQYLNSV------PQEEW 710
Query: 675 KLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYREDRIDEK 734
K L E++ + L L+PF PH+ EE +H + D + V SWP Y D K
Sbjct: 711 NRK---LLREIVEKLTLALSPFAPHLAEEFWHDLGNDSL----VVQQSWPSY-----DPK 758
Query: 735 AEKLGEL 741
A ++ E+
Sbjct: 759 ALEVEEV 765
>pir||B83077 isoleucyl-tRNA synthetase PA4560 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9950805|gb|AAG07948.1|AE004869_12 (AE004869)
isoleucyl-tRNA synthetase [Pseudomonas aeruginosa]
Length = 943
Score = 250 bits (632), Expect = 5e-65
Identities = 209/799 (26%), Positives = 349/799 (43%), Gaps = 95/799 (11%)
Query: 3 PKKYDPNEIEPKWQKYWLEEKIYKY--RLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWI 60
P K + EP+ K+W + +Y+ + ++P + + PP+ +G++H+GH ++
Sbjct: 16 PMKAGLPQREPETLKFWNDIGLYQKLRAIGGDRPKFVLHDGPPYANGSIHIGHAVNKILK 75
Query: 61 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKK-CVEWTWQAIEA 119
DII R K + GY+ + G+D HGLP E KVE G K+ P + ++ C E+ + IE
Sbjct: 76 DIIVRSKTLAGYDAPYVPGWDCHGLPIEHKVETTHG--KNLPADKTRELCREYAAEQIEG 133
Query: 120 MRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLA 179
+ FIR+G +WD Y TM+ +A ++L E K+ +++ PV WC C ++LA
Sbjct: 134 QKADFIRLGVLGEWDNPYKTMNFANEANEIRALAEMVKQDFVFKGLKPVNWCFDCGSALA 193
Query: 180 KAEVGYVEEEGYLYYIKLPLADGS--------------GYIPIATTRPELMPACVAVFVH 225
+AEV Y +++ + P+AD I I TT P +PA A+ VH
Sbjct: 194 EAEVEYADKKSPTIDVGFPVADADKLAAAFGLAALDKPAQIVIWTTTPWTIPANQALNVH 253
Query: 226 PD------DERYKHLV----------------GKKV-------------KLPIYEREVPI 250
P+ D ++LV GK V + P YER P+
Sbjct: 254 PEIDYALVDAGDRYLVLAEALVESCLARYQREGKVVATAKGEALELINFRHPFYERLSPV 313
Query: 251 LADEDVDPNFGTGAVYNCTYGDEQDIVWQKRY---NLPVIIAINEDGTMNENAGPYAGLK 307
+ V + GTG V++ E D KRY N ++ + +G ++ + G
Sbjct: 314 YLADYVALDAGTGIVHSSPAYGEDDFYTCKRYGMSNDDILSPVQSNGVYVDSLPFFGGQF 373
Query: 308 VEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRV------- 360
+ +A + LE++G L E I H + H R P+ QWF+ +
Sbjct: 374 IWKANPNVVAKLEEVGSLLAHETINHSYM-HCWRHK--TPLIYRATAQWFVGMDKQPRQG 430
Query: 361 KDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCK-NGHII 419
+ ++ + + P RL DW ISRQR +G P PF++ K +G +
Sbjct: 431 ASLRERALEAITQTEFVPGWGQARLHGMIAGRP-DWCISRQRNWGVPIPFFLHKASGELH 489
Query: 420 P----------AREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITR 469
P R E ++ F E A+ E + D LD W DS T
Sbjct: 490 PRTVELMEEVAQRVEKEGIEAWFKLDAAELLGEEAAQYEKINDTLDVWFDSG-----TTH 544
Query: 470 WHEAIKGDEEAKKWFEHNFPTA-LRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGM 528
WH ++G + P A L +G+D R W ++ + P++ ++ +G
Sbjct: 545 WH-VLRGSHRIG---HASGPVADLYLEGSDQHRGWFHSSLLTGCAIDNHAPYRQLLTHGF 600
Query: 529 VAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQK 588
GRKMSKS GN V P VI GAD LRLW A + + + + ++
Sbjct: 601 TVDESGRKMSKSLGNTVVPQTVIDTLGADILRLWVASTDYSGEIAVSQQILQRSADAYRR 660
Query: 589 VWNIYRFAERHIKDFD--YEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRE 646
+ N RF ++ FD + E+ LDRW + R + + E YRF + +
Sbjct: 661 IRNTTRFLLSNLNGFDPATDLLPPQEMLALDRWAVDRALLLQREIEEAYREYRFWNVYSK 720
Query: 647 LMTFIWHEVADDYIEMVKYRLY--GDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEI 704
+ F E+ Y++++K R Y G + ++ + AL+ + ++ +AP + EE+
Sbjct: 721 VHNFCVQELGGFYLDIIKDRQYTTGANSVARRSCQTALFHIAEALVRWIAPILAFTAEEV 780
Query: 705 YHAMFKDKIGEKSVHLLSW 723
+ + ++ +SV L +W
Sbjct: 781 WKFLPGER--AESVMLATW 797
>pir||D82293 isoleucyl-tRNA synthetase VC0682 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9655121|gb|AAF93847.1|
(AE004154) isoleucyl-tRNA synthetase [Vibrio cholerae]
Length = 949
Score = 249 bits (629), Expect = 1e-64
Identities = 203/786 (25%), Positives = 341/786 (42%), Gaps = 97/786 (12%)
Query: 3 PKKYDPNEIEPKWQKYWLEEKIYKY--RLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWI 60
P + D + EP+ + W +E +Y + + K S+ + PP+ +G +H+GH L+
Sbjct: 16 PMRGDLAKREPEMLQRWYQEDLYGAIRQAKKGKKSFVLHDGPPYANGDIHIGHALNKILK 75
Query: 61 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGIT--KDQPEEFLKKCVEWTWQAIE 118
D+I + K + G++ + G+D HGLP EL VEK+ G K EF +KC E+ +E
Sbjct: 76 DVIIKSKTLSGFDAPYIPGWDCHGLPIELMVEKKVGKPGQKVTAAEFREKCREYAAGQVE 135
Query: 119 AMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSL 178
++ F R+G +WD Y TMD +A + ++L + G + + PV+WC C ++L
Sbjct: 136 GQKESFKRLGILGEWDKPYRTMDFVTEANIIRALGKIADNGHLLKGFKPVHWCTDCGSAL 195
Query: 179 AKAEVGYVEEEGYLYYIKLPLAD-----------------GSGYIPIATTRPELMPACVA 221
A+AEV Y + ++ AD G I I TT P +PA A
Sbjct: 196 AEAEVEYKNKVSPSIDVRFKAADEAAVLAKFGLAAGHEGKGDVSIVIWTTTPWTLPANRA 255
Query: 222 VFVHPDDE------------------------------RYKHLVG---------KKVKLP 242
V + D E + H +G + + P
Sbjct: 256 VCLRADLEYVLIQVEGEQPERIIVASELAKSVMDRAGIEHFHNLGFATGADLELVQFQHP 315
Query: 243 IYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGP 302
Y VP + + V + GTG V+ ++D ++Y L V + +G +
Sbjct: 316 FYSFTVPAILGDHVTTDSGTGVVHTAPGHGQEDFAVGQQYGLEVANPVGSNGVYLPDTEL 375
Query: 303 YAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKD 362
+AG V +A + E L++ G L +H H R PI QWF+ ++
Sbjct: 376 FAGQHVFKANDSVLEVLKEKGALLHHHAYEHSY-PHCWRHK--TPIIFRATPQWFVSMEQ 432
Query: 363 --FTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIP 420
++ + K ++W P+ R++ +W ISRQR +G P +V K +
Sbjct: 433 AGLREQALTAIKGVHWMPDWGQSRIEGMVAGRP-EWCISRQRTWGVPIALFVHKETAELH 491
Query: 421 AREEDL--PVDPRFDKPPVEK------CPVCGAE----IEPVTDVLDCWVDSSITPLIIT 468
DL V ++ ++ + GAE E V D LD W DS +T +
Sbjct: 492 PNSADLIEKVAQLVEQKGIQAWWDLDTAELLGAEDAANYEKVLDTLDVWFDSGVTHSAVV 551
Query: 469 RWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGM 528
+ G EA + E G+D R W ++ + + GK P+K+++ +G
Sbjct: 552 DARQEFNG-AEADMYLE----------GSDQHRGWFQSSLISSVAMKGKAPYKEVLTHGF 600
Query: 529 VAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQK 588
V GRKMSKS GNVVAP +V K GAD LRLW A + E + + ++
Sbjct: 601 VVDGQGRKMSKSIGNVVAPQDVTNKLGADILRLWVASTDYTGEVAVSDEILKRSADAYRR 660
Query: 589 VWNIYRFAERHIKDFDYEKYKDI----ELEPLDRWILSRLHRIIKFATEELERYRFNLIT 644
+ N RF ++ F+ DI ++ LDRW + R + + + Y + +
Sbjct: 661 IRNTARFFLANLNGFN--PTTDIIPVEDMVALDRWAVGRALAAQQEIIQAYQDYNLHAVV 718
Query: 645 RELMTFIWHEVADDYIEMVKYRLYGDDE--ESKLKAKVALYELLYNVMLLLAPFVPHITE 702
+ LM F E+ Y++++K R Y ++ + AL+ ++ ++ +AP + +
Sbjct: 719 QRLMNFCSIEMGSFYLDVIKDRQYTAKRGGHAQRSCQTALFFIVEALVRWMAPIMSFTAD 778
Query: 703 EIYHAM 708
EI++AM
Sbjct: 779 EIWNAM 784
>gb|AAF50346.1| (AE003553) CG5660 gene product [Drosophila melanogaster]
Length = 994
Score = 247 bits (624), Expect = 4e-64
Identities = 214/829 (25%), Positives = 348/829 (41%), Gaps = 117/829 (14%)
Query: 6 YDPNEIEPK-WQKYWLEEKIYKYRLDENKP-SYAIDTPPPFTSGTLHLGHVLSHTWIDII 63
Y P +E W++ + + K K +Y + PPP +G LHLGH L T D+I
Sbjct: 43 YQPQPVENAYWEREHRQANLPKASASSCKRGTYRMLLPPPNVTGNLHLGHALMATVQDVI 102
Query: 64 ARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCV----EWTWQAIEA 119
AR + GY V + G D+ G+ T++ VE+ ++ + L + W W+A +
Sbjct: 103 ARQREQLGYQVDWVPGTDHAGIATQVVVERTIAASQAKTRHELGRSAFLDEVWRWKAEKG 162
Query: 120 --MRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTS 177
+ + ++G +W EY TMD+ AV + +++GLI R V WC R++
Sbjct: 163 AGIVQDLRQLGCKLNWQREYFTMDEQQAHAVNVAFERLFEEGLIQRRNSVVNWCTALRSA 222
Query: 178 LAKAEVGYVEEE----------------GYLYYIKLPLADGSGY-------IPIATTRPE 214
++ EV VE G +Y + DG I ++TTRPE
Sbjct: 223 ISDIEVDSVEITEPVEISVPGYDHKVLFGRMYDFAYHVVDGEALPDGSVEEIVVSTTRPE 282
Query: 215 LMPACVAVFVHPDDERY---KHLVGKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYG 271
+ VAV VHP D RY +++ K+K P + +P++ D VD FGTGAV
Sbjct: 283 TILGDVAVAVHPLDPRYAKYRNIDQVKLKHPFRDDTIPLVFDITVDQEFGTGAVKITPAH 342
Query: 272 DEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKI 331
D+ D R+ L E G + + Y G+ EAR I LE+M LL ++
Sbjct: 343 DKFDFELATRHKLEPRQVFTETGLVVDAYSEYKGIPRFEARDLIVNRLEEMDLL---RQV 399
Query: 332 KHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKV--AKEINWYPEDMFLRLKDWA 389
+ ++ S IE + QWF++ KD + + + + P + + W
Sbjct: 400 RSHTMQLPICSRSKDVIEYMILPQWFLKCKDLAKDALSELHSGRLQILPPNFETEWERWL 459
Query: 390 ESMDWDWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVDPRFDKPPVEKCP-VCGAE-- 446
+ DW ISRQ +G P + +I ++ V +K +K + G+E
Sbjct: 460 QDSR-DWCISRQLWWGHQVPAY-----EVIDSQGNSQWVAALDEKTARQKAMRLIGSEEF 513
Query: 447 -IEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAF 505
++ DVLD W SS+ P W E + ++ +P + G DII W
Sbjct: 514 TLKRDPDVLDTWFSSSLLPFSTAGWPE---------ESYKERYPLDIMQTGHDIIFFWVA 564
Query: 506 YTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEV--------------- 550
+ KLTG+ P++ I++NG+V GRKMSKS GN+VAP +V
Sbjct: 565 RMMMLGLKLTGEAPFQRILLNGIVCDAHGRKMSKSIGNIVAPQQVVQGASLESLKAGLEQ 624
Query: 551 --------------------------IPKYGADALRLWTALAPPGEDH--PFKWETVDYN 582
I + G DALR +T ++ + H F N
Sbjct: 625 SCEAGIITPSELKASTIGMTQMFPNGIQECGTDALR-FTLMSHNIKSHFISFDVNACHTN 683
Query: 583 FRFLQKVWNIYRFAERHIKDF-----DYEKYKDIELEPLDRWILSRLHRIIKFATEELER 637
FL KVW RF K +E + + L DRWI+ RL + ++
Sbjct: 684 KLFLNKVWQAMRFTLGSAKGLGISLHQFETLEGVNLGLWDRWIVGRLAETLSVCSQSYSN 743
Query: 638 YRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFV 697
Y F+L T L TF + + D Y+E K + ++ + L + + +AP+
Sbjct: 744 YNFHLATAALKTFFYQYLCDTYLETTKPAIGNRSADAYIHVGTLTACLSWGLQ-AMAPYA 802
Query: 698 PHITEE-IYHAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKV 745
P + E + H + L +Y++++++E+ ++ + V
Sbjct: 803 PFVASELLQHVPLNIE--------LKLSDYKDEKLEEEVNEIVNICHNV 843
>pir||T28995 hypothetical protein ZC513.4 - Caenorhabditis elegans
>gi|1255429|gb|AAC48266.1| (U53155) strong similarity to
the carboxyl two-thirds of valyl-tRNA synthetases
[Caenorhabditis elegans]
Length = 933
Score = 243 bits (613), Expect = 8e-63
Identities = 223/848 (26%), Positives = 361/848 (42%), Gaps = 125/848 (14%)
Query: 41 PPPFTSGTLHLGHVLSHTWIDIIARYKRMRGYNVLFPQ---------------GFDNHGL 85
PPP +G LHLGH L+ D I R++R +G V F + GFD+ G+
Sbjct: 4 PPPNVTGKLHLGHALTVAVEDAICRHQRNQGNKVKFHEKLRCLFLCFQAEWIPGFDHAGI 63
Query: 86 PTELKVEKEFGITKDQP-----EEFLKKCVEWTWQAIEAMRKQFIRIGYSADWDLEYHTM 140
T++ VEK + EEF+K+C W + +R+Q R+G S DW Y+T+
Sbjct: 64 ATQVVVEKILAKNGKRRLEMTREEFVKECHLWGEKCSSEIRQQLTRMGASLDWTQSYYTL 123
Query: 141 DDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV--------GYVE----- 187
D + AV K+ ++ LI R + V+WCP ++L+ EV GY+
Sbjct: 124 DSKFSEAVTKAFCILEQEDLITRGKRLVHWCPTLSSTLSSQEVNRIDVPSDGYINLSSSS 183
Query: 188 ------EEGYLYYIKLPLADG-SGYIPIATTRPELMPACVAVFVHPDDERYKHLVGKKVK 240
+ G ++ I+ L D S +I + TTRPE + A VAV VHP+D+RY GK V
Sbjct: 184 GTRRRVKFGQMHVIRYNLVDSESEFIEVGTTRPETLFADVAVAVHPEDDRYSKFHGKHVW 243
Query: 241 LPIYE-REVPILADEDVDPNFGTGAVYNCTYGDEQDI-VWQK------RYNLPVIIAINE 292
P+ R++ ++ D V GTGAV D D +W + + + I+
Sbjct: 244 SPVTPGRKLFVITDSAVSVEKGTGAVKITPSHDALDYEIWNRWILNAGQNTIEEFACIDA 303
Query: 293 DGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLP 352
+G M + + G+ EAR+K+ + L ++G +KH + S IE
Sbjct: 304 EGKMTNSGEDFDGMDRFEAREKVIQKLSELG--NYNGLMKHEGAQVNICSRTGDIIEPRL 361
Query: 353 KKQWFIRVKDFTDEIVKVAK--EINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPF 410
+QWF+ KD K +I +PE RL DW E+ + W +SRQ +
Sbjct: 362 TEQWFLDCKDMFARSADAIKSGKIEVFPEYQSHRLADWFENQE-PWCLSRQL-------W 413
Query: 411 WVCKNGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRW 470
W GH IPA E G +++ DVLD W S++ PL+ W
Sbjct: 414 W----GHRIPAYNVPGQSKWMVTTDEEEARRELGDKMQQDPDVLDTWFSSALVPLVKNGW 469
Query: 471 HEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKL-TGKKPWKDIVINGMV 529
E + E G DI W I KL +G+ P+ +V++G+V
Sbjct: 470 LEGAPIQTPSLNVME---------TGWDISGFWVARMIALNMKLSSGETPFGKVVLHGLV 520
Query: 530 AGPDGRKMSKSYGNVVAPDEV-------------------------------------IP 552
+GRKMSKS GNV+ P +V I
Sbjct: 521 RDNEGRKMSKSLGNVIDPLDVLDGITFEKMIERVKSSAHEKEEIDNAVKDLTKRFPNGIS 580
Query: 553 KYGADALRL----WTALAPPGEDHPFKWETVDY-NFRFLQKVWNIYRFAERHIKDFDYEK 607
+ G DALR + L+ D P F K+WN+ + ++ + E
Sbjct: 581 RCGPDALRFALLKYDVLS---TDIPIDVSNAAIEGLHFCNKIWNLAAYYDQLAE--KCEV 635
Query: 608 YKDIELEPL-DRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYR 666
KD++ + L D WI++RL + + ++ +L L FI ++ D Y+E K
Sbjct: 636 IKDVDSDRLVDEWIMARLSTTVSTVDAHMNKFSLHLALSTLHKFITSDICDIYLESTKKA 695
Query: 667 LYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEY 726
L+ +D +A+ L +L ++ L F+P ++E IY +FK + G ++ P
Sbjct: 696 LWNNDIARIREARSILQRVLQPTLVQLNAFMPFVSEYIYERIFKRETGSILFDVVK-PSL 754
Query: 727 REDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYAL--ESYDDLKLIEKD 784
+E+ E+ +L +++ +R + + +P + A S +L+++ +
Sbjct: 755 FIFHRNEELEEAMKLITAMMAAIRSTRQTLQLPQRITFSGILEMAPTDTSPSELRILADE 814
Query: 785 IAGTMNIE 792
+ T E
Sbjct: 815 VTQTCGFE 822
>gb|AAA34712.1| (M19992) isoleucyl-tRNA synthetase (EC 6.1.1.5) [Saccharomyces
cerevisiae]
Length = 1073
Score = 240 bits (607), Expect = 4e-62
Identities = 244/937 (26%), Positives = 412/937 (43%), Gaps = 121/937 (12%)
Query: 29 LDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRMRGYNVLFPQGFDNHGLPTE 88
L ++KP ++ PPF +GT H GH+L+ T DI+ RY M G++V G+D HG+P E
Sbjct: 33 LTKDKPEFSFFDGPPFATGTPHYGHILASTIKDIVPRYATMTGHHVERRFGWDTHGVPIE 92
Query: 89 LKVEKEFGIT-KDQP-----EEFLKKCVEWTWQAIEAMRKQFIRIGYSADWDLEYHTMDD 142
++K+ GIT KD E + +C RK R+G D+D +Y TM
Sbjct: 93 HIIDKKLGITGKDDVFKYGLENYNNECRSIVMTYASDWRKTIGRLGRWIDFDNDYKTMYP 152
Query: 143 WYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLA--KAEVGYVEEEGYLYYIKLPLA 200
+ + + + ++KG +YR + + T L+ +A+ Y + I +
Sbjct: 153 SFMESTWWAFKQLHEKGQVYRGFKVMPYSTGLTTPLSNFEAQQNYKDVNDPAVTIGFNVI 212
Query: 201 DGSGYIPIA-TTRPELMPACVAVFVH------------------------------PDDE 229
+A TT P +P+ +++ V+ P +E
Sbjct: 213 GQEKTQLVAWTTTPWTLPSNLSLCVNADFEYVKIYDETRDRYFILLESLIKTLYKKPKNE 272
Query: 230 RYK--------HLVGKKVKLPIY--------EREVPILADEDVDPNFGTGAVYNC-TYGD 272
+YK LVG K + P++ E +++D+ V + GTG V+N +G+
Sbjct: 273 KYKIVEKIKGSDLVGLKYE-PLFPYFAEQFHETAFRVISDDYVTSDSGTGIVHNAPAFGE 331
Query: 273 EQDIVWQKRYNLP----VIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKK 328
E + K + + AI++ G ++ + G+ V++A K I + L G L
Sbjct: 332 EDNAACLKNGVISEDSVLPNAIDDLGRFTKDVPDFEGVYVKDADKLIIKYLTNTGNLLLA 391
Query: 329 EKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDMF-LRLKD 387
+I+H RS P+ WF+RVK+ +++ + +W P + R +
Sbjct: 392 SQIRHSY-PFCWRSD--TPLLYRSVPAWFVRVKNIVPQMLDSVMKSHWVPNTIKEKRFAN 448
Query: 388 WAESMDWDWVISRQRVFGTPFPFWVCKN-------GHIIPARE-------EDLPVDPRFD 433
W + DW +SR R +GTP P WV + G I E DL D D
Sbjct: 449 WIANAR-DWNVSRNRYWGTPIPLWVSDDFEEVVCVGSIKELEELTGVRNITDLHRDV-ID 506
Query: 434 KPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALR 493
K + G +++ + +V DCW +S P H + E+ FE P
Sbjct: 507 KLTIPSKQGKG-DLKRIEEVFDCWFESGSMPY--ASQHYPFENTEK----FEERVPANFI 559
Query: 494 PQGTDIIRTWAFYTIFRTFKLTGKKPWK-DIVINGMVAGPDGRKMSKSYGNVVAPDEVIP 552
+G D R W + L G P+K ++++G+V DGRKMSKS N P V+
Sbjct: 560 SEGLDQTRGWFYTLAVLGTHLFGSVPYKKSVIVSGIVLAADGRKMSKSLKNYPDPSIVLN 619
Query: 553 KYGADALRLWTALAP--PGEDHPFKWETV-DYNFRFLQKVWNIYRFAERHIK-------- 601
KYGADALRL+ +P E FK E V + + L WN ++F + I
Sbjct: 620 KYGADALRLYLINSPVLKAESLKFKEEGVKEVVSKVLLPWWNSFKFLDGQIALLKKMSNI 679
Query: 602 DFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIE 661
DF Y+ + + IL+ + +++ EE+ +Y+ + +L+ FI E+ + YI
Sbjct: 680 DFQYDDSVKSD-NVMAEMILASMQSLVQVIHEEMGQYKLYTVVPKLLNFI-DELTNWYIR 737
Query: 662 MVKYRLYGDD-EESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGE----- 715
+ RL G++ E LKA +L++ L+ + +APF P ++E IY K+ I E
Sbjct: 738 FNRRRLKGENVVEDCLKALNSLFDALFTFVRAMAPFTPFLSESIY-LRLKEYIPEAVLAK 796
Query: 716 -----KSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEH-VAI 769
+SVH LS+P +++ DE E + V+ R + + L L+ V +
Sbjct: 797 YGKDGRSVHFLSYPVVKKEYFDEAIETAVSRMQSVIDLGRNIREKKTISLKTPLKTLVIL 856
Query: 770 YALESY-DDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRI 828
++ ESY D++ ++ I +N+ + I E + V ++ +G + K ++
Sbjct: 857 HSDESYLKDVEALKNYIIEELNVRDVVITSDEAKYGVEYKAV-ADWPVLGKKLKKDAKKV 915
Query: 829 VEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDV 865
+ L + RE E+GK+E +EL K D+
Sbjct: 916 KDALPSVTSEQVREYLESGKLEV----AGIELVKGDL 948
>sp|P36422|SYI_TETTH ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|283498|pir||A42399 isoleucine--tRNA ligase (EC
6.1.1.5) - Tetrahymena thermophila
>gi|161801|gb|AAA30122.1| (M30942) transfer RNA-Ile
synthetase [Tetrahymena thermophila]
Length = 1081
Score = 240 bits (606), Expect = 5e-62
Identities = 246/981 (25%), Positives = 424/981 (43%), Gaps = 134/981 (13%)
Query: 17 KYWLEEKIYKYRLDENK--PSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRMRGYNV 74
K+W E +K +L++ K P + PPF +G H G++L+ T D++ RY G V
Sbjct: 25 KFWDEINAFKQQLEKTKDCPPFTFYDGPPFATGLPHYGNLLAGTIKDVVCRYASQNGKYV 84
Query: 75 LFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCVEWTWQAIEAMRKQFIRIG 128
G+D HGLP E +++K+ GIT Q +++ +C + + R R G
Sbjct: 85 ERRFGWDCHGLPVEYEIDKKLGITNRQEVLKMGVDKYNAECRSIVMRYAQEWRSIVNRFG 144
Query: 129 YSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV--GYV 186
D+D +Y T+D + +V + + KGL+YR + + C T L+ E Y
Sbjct: 145 RWVDFDNDYKTLDLKFMESVWWVFKQMFDKGLVYRGCKVMPYSNGCATVLSNFETQQNYK 204
Query: 187 EEEGYLYYIKLPLADGSGYIPIA-TTRPELMPACVAVFVHPDDERYK--------HLVGK 237
E + +I A+ IA TT P +P+ +A+ ++ D + K H +
Sbjct: 205 EVDDPSLFIAFKTAEDPKTKFIAWTTTPWTLPSNLALVINKDFDYVKVLDAKTQEHYILA 264
Query: 238 KVKLP-IYEREVP-----------------------------------ILADEDVDPNFG 261
+ +LP +Y+++ ILA + V + G
Sbjct: 265 ECRLPELYKKDKDGYKILEKFKGSELVGREYEPLFPYFLSRKQDGCFRILAGDFVTADAG 324
Query: 262 TGAVYNCTYGDEQDIVWQKRYNL----PVIIAINEDGTMNENAGPYAGLKVEEARKKIAE 317
TG V+ + D N+ + ++E+G +AG+ ++EA K I +
Sbjct: 325 TGIVHCAPGFGDDDYKVSVANNIIKPDDPPVPVDENGHFTNVVSDFAGVYIKEADKLIRK 384
Query: 318 DLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWY 377
+L++ GLL KH RS P+ WFI+V D+++ K+ W
Sbjct: 385 NLKERGLLLVDSSFKHNY-PFCWRSD--TPLIYKAVHCWFIKVTALKDDLLANNKKAYWV 441
Query: 378 PE-DMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGH---IIPAREEDLPVDPRFD 433
P+ R +W +++ DW SR R +G P P WV ++ I + EE + +
Sbjct: 442 PKFAQEGRFNNWLQNVS-DWCFSRSRFWGNPIPIWVSEDFEEVVCIGSVEELKKLTGATE 500
Query: 434 KPPVEKCPVCGAEIEP---------VTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWF 484
+ K + I + +V DCW +S P + H +EE F
Sbjct: 501 ITDLHKDFIDHLTIPSQKGKGVLRRIDEVFDCWFESGSMPY--GQQHYPFSMNEEE---F 555
Query: 485 EHNFPTALRPQGTDIIRTWAFYTI-FRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGN 543
FP +G D R W FYT+ + L P+K++++NG+V DG+KMSKS N
Sbjct: 556 SKRFPADFIGEGIDQTRGW-FYTLNVISTALRNSNPYKNLIVNGIVLAADGKKMSKSKKN 614
Query: 544 VVAPDEVIPKYGADALRLWTALAP--PGEDHPFKWETVDYNFRFLQKVW-NIYRFAERHI 600
P + KY DA+RL+ +P E+ FK E V + + W N Y+F + I
Sbjct: 615 YDDPLLIASKYSVDAIRLYMINSPLVRAEEMSFKSEGVFAVKKDIFLPWYNAYKFLIQSI 674
Query: 601 --------KDFDYEKYKDIE----LEPLDRWILSRLHRIIKFATEELERYRFNLITRELM 648
KD+ + + ++ P DRWI+ +I + E+E+Y + L+
Sbjct: 675 TRWELATGKDYMFNEQLSVDTTKLTNPTDRWIIISCQNLINYVRIEMEKYHLYNVVPRLI 734
Query: 649 TFIWHEVADDYIEMVKYRLYGD----DEESKLKAKVALYELLYNVMLLLAPFVPHITEEI 704
F+ + + YI + + RL GD ++E+ L L+ ++ N +L++P VP ITE
Sbjct: 735 HFL-ENLTNWYIRLNRNRLKGDYGLEEQETSLN---VLFNVILNSTILMSPLVPFITESF 790
Query: 705 YHAMFK-----DKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMP 759
Y + K E+S+H L P +++ +DEK E+ E + +++ R + +
Sbjct: 791 YQNLRKVIPKGSSYLEESIHFLRIPTPKQELLDEKIERNFERMQNIINFARTLREKRKVS 850
Query: 760 LNAKLEHVAI--YALESYDDLK----LIEKDIAGTMNIEKLEIFKGEPQLEERIVEVK-- 811
L + + + E +D LK IE +I + ++ V++K
Sbjct: 851 LKQPIMSLTVINQDQEFHDSLKDYIQYIEDEINTPSILHEIN--------TANYVDLKAI 902
Query: 812 PNYKRIGPRYGKLVPRIVEHLKNNAESIAREIKENGKVEFEIDGEKVELTKEDVMIK--- 868
PN+K +G + GK + LK A +++ + E K ID +L ED I
Sbjct: 903 PNHKLLGQKLGK---EYNKDLKAAAGNLSAKDIETLKTTGSIDLVGKKLLLEDFTITQNY 959
Query: 869 KEVFSEGERVETAVVDDIVIL 889
K+ +S G+ +E ++++L
Sbjct: 960 KKEYSSGD-LELGGEGEVILL 979
>pir||T38777 probable valyl trna synthetase - fission yeast
(Schizosaccharomyces pombe) >gi|4490646|emb|CAB38577.1|
(Z98762) putative valyl trna synthetase
[Schizosaccharomyces pombe]
Length = 950
Score = 239 bits (603), Expect = 1e-61
Identities = 227/915 (24%), Positives = 397/915 (42%), Gaps = 115/915 (12%)
Query: 34 PSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEK 93
P + I PPP +G LH+GH L+ T D +AR+ M GY V F G D+ G+ T+ VEK
Sbjct: 58 PMFPILLPPPNITGKLHIGHALTITIQDALARFYAMHGYKVSFRPGTDHAGIATQSVVEK 117
Query: 94 ---EFGITKDQ--PEEFLKKCVEWTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAV 148
+ G+ ++Q +E L W + +++ Q DWD ++TMD AV
Sbjct: 118 YLQKKGVYRNQLSKDELLSSIHSWQVKYQKSIINQLKSFEAIFDWDNIFYTMDQNRSEAV 177
Query: 149 QKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV----------GYVE----EEGYLYY 194
++ + + GLIYR V WCPK ++++ EV YV+ E G+LY
Sbjct: 178 NEAFISLFNAGLIYRANRFVNWCPKLESAVSDIEVESQQINKPVTKYVDNTPVEFGWLYE 237
Query: 195 IKLPL-ADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVGKKVKLP-IYEREVPILA 252
I L + + ++TTRPE + A+ V P DERYK VG+ VK P I + +P++
Sbjct: 238 ISYQLEGSDNEQLNVSTTRPETIFGDRAIAVSPHDERYKKYVGRFVKHPLIDDLLIPVIC 297
Query: 253 DEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEAR 312
D VD +FGTG + D KR+N+ + +++ G + + G+ +AR
Sbjct: 298 DNAVDRHFGTGVLKITPMHSIVDYEIAKRHNIDCVSIMDKSGNLINCSKEVNGMNRLKAR 357
Query: 313 KKIAEDLEKMGLLYKKEKIKHR-VLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVA 371
KI L++ L E++ H +L R+ + ++P QW++ V E++K +
Sbjct: 358 SKIVRLLQQRNRLV--EQVPHSLILSVCSRTGDVIEPVMVP--QWYLSVDSLKKEVLKSS 413
Query: 372 KEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVDPR 431
++ P W + M DW ISRQ +G P W + L D
Sbjct: 414 NKLKLVPSLARKEWDSWFKKMG-DWCISRQIWWGHQIPVW------------KILEEDKW 460
Query: 432 FDKPPVEKC--PVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFP 489
P EK G + +DVLD W S++ PL W ++ + P
Sbjct: 461 IAAPNYEKALQLSVGKSVSQDSDVLDTWFSSALLPLSAFGWPKS-----------KDIQP 509
Query: 490 TALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDE 549
G DI+ W + + P+K+I+++ +V +GRKMSKS GNV+ P +
Sbjct: 510 LPFIESGQDILFFWIARMALLCKYFSNELPFKEIILHPLVRDSEGRKMSKSLGNVIDPMD 569
Query: 550 V-------------------------------------IPKYGADALRLWTALAPPGEDH 572
+ IP G D R L E
Sbjct: 570 IINGVTLENMKKALLEGNLPISEVHKSSKQMEKAFPNGIPAQGIDIFRYGLFLCLHHEQR 629
Query: 573 -PFKWETVDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIE---LEPLDRWILSRLHRII 628
+ RF+ K+WN+ R+ ++ + K D + + L S+LH +
Sbjct: 630 ILLDMNSFSDAHRFVSKLWNLARYFNQYKDKENPLKLTDSQRQRISLLKMATYSKLHHAV 689
Query: 629 KFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYN 688
+ E E+ +F + F+ ++++ Y+E+ ++ + D + S + ++L+
Sbjct: 690 EGVKESFEQRKFFNAADIMKNFLLNDLSSVYVELTRFDV-KDSKSSAYEVYRVFSDILHI 748
Query: 689 VMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYREDRI---DEKAEKLGELARKV 745
+ L+ P VP I+ + H+ + K+ LS+P +++ + D +AE + + A V
Sbjct: 749 FLKLIHPIVPCISGVMLHSKIIPE--RKNSEFLSFPTSQQECLLVHDNQAEVVVQNAYDV 806
Query: 746 VSEMRKYKN--------SHGMPLNAKLEHVAIY--ALESYDDLKLIEKDIAGTMNIEKLE 795
+ ++RK ++ H + ++ LE + + A+E +LKL T+++ + +
Sbjct: 807 LIQLRKLESPLNKSPSREHTVYISTSLEPLKYFYDAIEQSTNLKLKSISQEDTIDLMRNQ 866
Query: 796 IFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKNNAESIAREIKENG--KVEFEI 853
F + I+ V K++ P K + + ++ L+ + I +G K I
Sbjct: 867 TFILSRISSDTILLVP---KKLYPSKRKKLRKNLDDLQKKLDKIQHTTSSSGYEKAPSYI 923
Query: 854 DGEKVELTKEDVMIK 868
+ EL K D+++K
Sbjct: 924 KLKNCELQK-DILVK 937
>dbj|BAA01304.1| (D10483) isoleucyl-tRNA ligase [Escherichia coli]
Length = 936
Score = 236 bits (597), Expect = 6e-61
Identities = 209/797 (26%), Positives = 342/797 (42%), Gaps = 95/797 (11%)
Query: 3 PKKYDPNEIEPKWQKYWLEEKIYKY--RLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWI 60
P + D + EP W ++ +Y + K ++ + PP+ +G++H+GH ++
Sbjct: 16 PMRGDLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGSIHIGHSVNKILK 75
Query: 61 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQ--PEEFLKKCVEWTWQAIE 118
DII + K + GY+ + G+D HGLP ELKVE+E+G ++ EF KC E+ ++
Sbjct: 76 DIIVKSKGLSGYDSPYVPGWDCHGLPIELKVEQEYGKPGEKFTAAEFRAKCREYAATQVD 135
Query: 119 AMRKQFIRIGYSADWDLEYHTM--DDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRT 176
RK FIR+G DW Y TM +W KA + ++L + G +++ PV+WC CR+
Sbjct: 136 GQRKDFIRLGVLGDWSHPYLTMGLQNW-KANIIRALGKIIGNGHLHKGAKPVHWCVDCRS 194
Query: 177 SLAKAEVGY--------------VEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAV 222
+LAK ++ V+++ + +G + I TT P +PA A+
Sbjct: 195 ALAKRKLSITTKLLRPSTLLSRAVDQDALKAKFAVSNVNGPISLVIWTTTPWTLPANRAI 254
Query: 223 FVHPD-DERYKHLVGKKVKL--------------------------------PIYEREVP 249
+ PD D + G+ V L P +VP
Sbjct: 255 SIAPDFDYALVQIDGQAVILAKDLVESVMQRIGVTDSRHGKRCGAGAAAFTHPFMGFDVP 314
Query: 250 ILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYA-GLKV 308
+ + V + GTGAV+ D V ++Y L + DGT P G+ V
Sbjct: 315 AILGDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNV 374
Query: 309 EEARKKIAEDLEKMGLLYKKEKIKHRV---LRHTERSSCMAPIELLPKKQWFIRV--KDF 363
+A +A L++ G L EK++H RH PI QWF+ + K
Sbjct: 375 FKANDIVAALLQEKGALLHVEKMQHSYPCCWRHK------TPIIFRATPQWFVSMDQKGL 428
Query: 364 TDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPARE 423
+ +K K + W P+ R++ + DW ISRQR +G P +V K+ + R
Sbjct: 429 RAQSLKEIKGVQWIPDWGQARIESMVANRP-DWCISRQRTWGVPMSLFVHKDTEELHPRT 487
Query: 424 EDL--PVDPRFDKPPVEKC------PVCGAEIEP---VTDVLDCWVDSSITPLIITRWHE 472
+L V R + ++ + G E + V D LD W DS T +
Sbjct: 488 LELMEEVAKRVEVDGIQAWWDLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVVDVRP 547
Query: 473 AIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGP 532
G A + E G+D R W ++ + + GK P++ ++ +G
Sbjct: 548 EFAG-HAADMYLE----------GSDQHRGWFMSSLMISTAMKGKAPYRQVLTHGFTVDG 596
Query: 533 DGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNI 592
GRKMSKS GN V+P +V+ K GAD LRLW A + E + +++ N
Sbjct: 597 QGRKMSKSIGNTVSPQDVMNKLGADILRLWVASTDYTGEMAVSDEILKRAADTYRRIRNT 656
Query: 593 YRFAERHIKDFDYEK--YKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTF 650
RF ++ FD K K E+ LDRW + R K ++ + + LM F
Sbjct: 657 ARFLLANLNGFDPAKDMVKRREMVVLDRWAVVVRKRHRKTSSRRTKHTISTKWYKRLMRF 716
Query: 651 IWHEVADDYIEMVKYRLYGDDEES--KLKAKVALYELLYNVMLLLAPFVPHITEEIYHAM 708
E+ Y++++K R Y S + + ALY + ++ +AP + +E++ +
Sbjct: 717 CSVEMGSFYLDIIKDRQYYAKGHSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYL 776
Query: 709 FKDKIGEKSVHLLSWPE 725
++ EK V W E
Sbjct: 777 PGER--EKYVFTGEWYE 791
>gi|8922356 hypothetical protein FLJ10326 [Homo sapiens]
>gi|7022287|dbj|BAA91544.1| (AK001188) unnamed protein
product [Homo sapiens]
Length = 764
Score = 235 bits (594), Expect = 1e-60
Identities = 204/728 (28%), Positives = 308/728 (42%), Gaps = 114/728 (15%)
Query: 69 MRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPE--EFLKKCVEWTWQAIEAMRKQFIR 126
M G + F G+D HGLP E+KV E G E KK + AIE + FIR
Sbjct: 1 MNGSKIHFVPGWDCHGLPIEIKVLSELGREAQNLSAMEIRKKARSFAKAAIEKQKSAFIR 60
Query: 127 IGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVGYV 186
G ADW+ Y+T D Y+A ++ + Y KGL+YR PV+W P RT+LA+AE+ Y
Sbjct: 61 WGIMADWNNCYYTFDGKYEAKQLRTFYQMYDKGLVYRSYKPVFWSPSSRTALAEAELEYN 120
Query: 187 EEE-GYLYYIKLPLA----------DGSGYIPIA--TTRPELMPACVAVFVHPDDERYKH 233
E Y+K PL DGS + I TT+P +PA AV P+ +
Sbjct: 121 PEHVSRSIYVKFPLLKPSPKLASLIDGSSPVSILVWTTQPWTIPANEAVCYMPESKYAVV 180
Query: 234 LVGKKVKLPIY--------------------------------------EREVPILADED 255
K L + ++ P+L
Sbjct: 181 KCSKSGDLYVLAADKVASVASTLETTFETISTLSGVDLENGTCSHPLIPDKASPLLPANH 240
Query: 256 VDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLK--VEEARK 313
V GTG V+ +D ++NLP+ ++EDG + AGP K +EE
Sbjct: 241 VTMAKGTGLVHTAPAHGMEDYGVASQHNLPMDCLVDEDGVFTDVAGPELQNKAVLEEGTD 300
Query: 314 KIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKE 373
+ + L+ L K+EK+ H P+ + KQWFI + D ++ K+
Sbjct: 301 VVIKMLQTAKNLLKEEKLVHSYPYDWRTKK---PVVIRASKQWFINITDIKTAAKELLKK 357
Query: 374 INWYPEDMFLRLKDWAESMDWD--WVISRQRVFGTPFPFWVCKNG-----------HIIP 420
+ + P L E MD W ISRQRV+G P P + K HI+
Sbjct: 358 VKFIPGSA---LNGMVEMMDRRPYWCISRQRVWGVPIPVFHHKTKDEYLINSQTTEHIVK 414
Query: 421 AREEDLPVDPRFDKPPVEKCP------VCGA---EIEPVTDVLDCWVDSSITPLIITRWH 471
E+ D + PP + P V G E P D+LD W DS T W
Sbjct: 415 LVEQH-GSDIWWTLPPEQLLPKEVLSEVGGPDALEYVPGQDILDIWFDSG------TSWS 467
Query: 472 EAIKG-DEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVA 530
+ G D+ A + E G D + W ++ + + P+K ++++G
Sbjct: 468 YVLPGPDQRADLYLE----------GKDQLGGWFQSSLLTSVAARKRAPYKTVIVHGFTL 517
Query: 531 GPDGRKMSKSYGNVVAPDEVI---------PKYGADALRLWTALAPPGEDHPFKWETVDY 581
G G KMSKS GNV+ PD V+ P YGAD LR W A + + ++
Sbjct: 518 GEKGEKMSKSLGNVIHPDVVVNGGQDQSKEPPYGADVLRWWVADSNVFTEVAIGPSVLNA 577
Query: 582 NFRFLQKVWNIYRFAERHIKDFDYE--KYKDIELEPLDRWILSRLHRIIKFATEELERYR 639
+ K+ N RF ++ DF+ E ++ +D+++L L + TE ++Y
Sbjct: 578 ARDDISKLRNTLRFLLGNVADFNPETDSIPVNDMYVIDQYMLHLLQDLANKITELYKQYD 637
Query: 640 FNLITRELMTFIWHEVADDYIEMVKYRLYGDDEE--SKLKAKVALYELLYNVMLLLAPFV 697
F + R L TF E+++ Y ++K RLY + E + + AL E+L ++ AP +
Sbjct: 638 FGKVVRLLRTFYTRELSNFYFSIIKDRLYCEKENDPKRRSCQTALVEILDVIVRSFAPIL 697
Query: 698 PHITEEIY 705
PH+ EE++
Sbjct: 698 PHLAEEVF 705
>gi|11426198 hypothetical protein FLJ10326 [Homo sapiens]
Length = 871
Score = 235 bits (594), Expect = 1e-60
Identities = 204/728 (28%), Positives = 308/728 (42%), Gaps = 114/728 (15%)
Query: 69 MRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPE--EFLKKCVEWTWQAIEAMRKQFIR 126
M G + F G+D HGLP E+KV E G E KK + AIE + FIR
Sbjct: 1 MNGSKIHFVPGWDCHGLPIEIKVLSELGREAQNLSAMEIRKKARSFAKAAIEKQKSAFIR 60
Query: 127 IGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVGYV 186
G ADW+ Y+T D Y+A ++ + Y KGL+YR PV+W P RT+LA+AE+ Y
Sbjct: 61 WGIMADWNNCYYTFDGKYEAKQLRTFYQMYDKGLVYRSYKPVFWSPSSRTALAEAELEYN 120
Query: 187 EEE-GYLYYIKLPLA----------DGSGYIPIA--TTRPELMPACVAVFVHPDDERYKH 233
E Y+K PL DGS + I TT+P +PA AV P+ +
Sbjct: 121 PEHVSRSIYVKFPLLKPSPKLASLIDGSSPVSILVWTTQPWTIPANEAVCYMPESKYAVV 180
Query: 234 LVGKKVKLPIY--------------------------------------EREVPILADED 255
K L + ++ P+L
Sbjct: 181 KCSKSGDLYVLAADKVASVASTLETTFETISTLSGVDLENGTCSHPLIPDKASPLLPANH 240
Query: 256 VDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLK--VEEARK 313
V GTG V+ +D ++NLP+ ++EDG + AGP K +EE
Sbjct: 241 VTMAKGTGLVHTAPAHGMEDYGVASQHNLPMDCLVDEDGVFTDVAGPELQNKAVLEEGTD 300
Query: 314 KIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKE 373
+ + L+ L K+EK+ H P+ + KQWFI + D ++ K+
Sbjct: 301 VVIKMLQTAKNLLKEEKLVHSYPYDWRTKK---PVVIRASKQWFINITDIKTAAKELLKK 357
Query: 374 INWYPEDMFLRLKDWAESMDWD--WVISRQRVFGTPFPFWVCKNG-----------HIIP 420
+ + P L E MD W ISRQRV+G P P + K HI+
Sbjct: 358 VKFIPGSA---LNGMVEMMDRRPYWCISRQRVWGVPIPVFHHKTKDEYLINSQTTEHIVK 414
Query: 421 AREEDLPVDPRFDKPPVEKCP------VCGA---EIEPVTDVLDCWVDSSITPLIITRWH 471
E+ D + PP + P V G E P D+LD W DS T W
Sbjct: 415 LVEQH-GSDIWWTLPPEQLLPKEVLSEVGGPDALEYVPGQDILDIWFDSG------TSWS 467
Query: 472 EAIKG-DEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVA 530
+ G D+ A + E G D + W ++ + + P+K ++++G
Sbjct: 468 YVLPGPDQRADLYLE----------GKDQLGGWFQSSLLTSVAARKRAPYKTVIVHGFTL 517
Query: 531 GPDGRKMSKSYGNVVAPDEVI---------PKYGADALRLWTALAPPGEDHPFKWETVDY 581
G G KMSKS GNV+ PD V+ P YGAD LR W A + + ++
Sbjct: 518 GEKGEKMSKSLGNVIHPDVVVNGGQDQSKEPPYGADVLRWWVADSNVFTEVAIGPSVLNA 577
Query: 582 NFRFLQKVWNIYRFAERHIKDFDYE--KYKDIELEPLDRWILSRLHRIIKFATEELERYR 639
+ K+ N RF ++ DF+ E ++ +D+++L L + TE ++Y
Sbjct: 578 ARDDISKLRNTLRFLLGNVADFNPETDSIPVNDMYVIDQYMLHLLQDLANKITELYKQYD 637
Query: 640 FNLITRELMTFIWHEVADDYIEMVKYRLYGDDEE--SKLKAKVALYELLYNVMLLLAPFV 697
F + R L TF E+++ Y ++K RLY + E + + AL E+L ++ AP +
Sbjct: 638 FGKVVRLLRTFYTRELSNFYFSIIKDRLYCEKENDPKRRSCQTALVEILDVIVRSFAPIL 697
Query: 698 PHITEEIY 705
PH+ EE++
Sbjct: 698 PHLAEEVF 705
>dbj|BAA28842.1| (AB008528) Valyl tRNA Synthetase [Trichomonas vaginalis]
Length = 722
Score = 235 bits (592), Expect = 2e-60
Identities = 192/703 (27%), Positives = 305/703 (43%), Gaps = 91/703 (12%)
Query: 103 EEFLKKCVEWTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIY 162
E FL++ +W + Q +G S W Y+T+D+ +V + ++ + +GL+Y
Sbjct: 15 EYFLEEAHKWVESKSGTILSQLRDMGSSLAWKDTYYTLDEKRSESVIAAFIKLFDEGLVY 74
Query: 163 REEHPVYWCPKCRTSLAKAEVGYVEEE-----------------GYLYYIKLPLADGSGY 205
R E V W +T+++ AEV Y+ G + + + D G
Sbjct: 75 RSERLVNWDCALKTAISDAEVEYITLTKRTKLNVPNHKYPQYPFGVMTHFYYEICDKDGK 134
Query: 206 -----IPIATTRPELMPACVAVFVHPDDERYKHLVGKKVKLPIYEREVPILADED-VDPN 259
+ IATTR E M AV ++P D RY HL G V PI E +PI+ DE VD N
Sbjct: 135 KTGEKVEIATTRLETMLGDTAVAINPKDARYNHLHGMYVWHPIREVPIPIIQDEILVDMN 194
Query: 260 FGTGAVYNCTYGDEQDIVWQKRY-NLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAED 318
FGTG V D D KR+ + +I + DG + G ++G+ +AR ++ +
Sbjct: 195 FGTGVVKVTPGHDPNDYEVYKRHPEIGLISILTPDGAIAPGYGQFSGMMRFDARVEMVKW 254
Query: 319 LEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAK--EINW 376
+++ GL YK+EK L T+R + + P QWF+ D +K E+
Sbjct: 255 MKERGL-YKEEKDHEMRLGITQRGHDIVEQVITP--QWFVNTTDMAARAIKAVDDGELKI 311
Query: 377 YPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPF--------WVCKNGHIIPAREEDLPV 428
P++ + K W E++ W ISRQ ++G P W NG + A ++ +
Sbjct: 312 VPDEFVVDWKKWHENIR-PWCISRQLMWGHRIPAYRVQIDGKWAEGNGEWVAAASQEEAI 370
Query: 429 DPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNF 488
VE V +E DVLD W S++ P W +E ++F
Sbjct: 371 AKGAKANNVEPSRVT---VEQDPDVLDTWFSSALLPFSGVGWPS---NEERLNRYF---- 420
Query: 489 PTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPD 548
P ++ G DI+ W + + LT K P+ I+++ +V GRKMSKS GNV+ P
Sbjct: 421 PNSILETGWDILTFWVSRMVMMSLTLTNKVPFHTILLHPLVRDAQGRKMSKSLGNVIDPR 480
Query: 549 EV-------------------------------------IPKYGADALRL-WTALAPPGE 570
V IP+ G DA+RL + A
Sbjct: 481 HVINGIELEDLVAEIENSTFDDKEKKIAIDGRKADFPNGIPQCGTDAMRLALCSFAGANR 540
Query: 571 DHPFKWETVDYNFRFLQKVWNIYRFAERHIKDFDYE-KYKDIELE---PLDRWILSRLHR 626
+ F K+WN RFA + F+ E +KD++ PLD+W L +L
Sbjct: 541 TANLNVSVIVSYRNFCNKMWNAVRFALPNFDKFNPEDSHKDLDASKTTPLDKWALKKLSL 600
Query: 627 IIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELL 686
IK AT L+ ++ + F E Y+E +K + GDD +K LYE +
Sbjct: 601 AIKAATAGLQDFKMADAVNGMTHFFHDEFCSVYLEGIKPIVNGDDAAAKEVVAAVLYECI 660
Query: 687 YNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYRED 729
+ M +L PF+P++TEE++ + + + +S+ L +P E+
Sbjct: 661 ESTMRMLHPFMPYVTEELWQHLPR-RFNVESIMLAPYPLVNEE 702
>pir||D75307 leucyl-tRNA synthetase - Deinococcus radiodurans (strain R1)
>gi|6459971|gb|AAF11720.1|AE002050_6 (AE002050)
leucyl-tRNA synthetase [Deinococcus radiodurans]
Length = 874
Score = 233 bits (588), Expect = 7e-60
Identities = 233/833 (27%), Positives = 337/833 (39%), Gaps = 201/833 (24%)
Query: 4 KKYDPNEIEPKWQKYWLEEKIYKYRLDENKPS---YAIDTPPPFTSGTLHLGHVLSHTWI 60
++Y+P+ IE KWQ W E +YK+ DEN P YA+ T P+ SG LH+GH ++
Sbjct: 67 ERYNPHAIEQKWQGQWQESGLYKF--DENAPGEKFYAL-TMFPYPSGNLHIGHWYANVAP 123
Query: 61 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAM 120
D AR+ RMRGYNVLFP FD GLP E K P WT+ IE M
Sbjct: 124 DARARWLRMRGYNVLFPMAFDAFGLPAENAAIK----NNTNP-------ATWTYANIERM 172
Query: 121 RKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAK 180
QF R+G DW ++ T D Y Q +EF+K+GL Y++ V WCPK +T LA
Sbjct: 173 TGQFSRMGTMIDWSRKFATCDPEYYRWNQWFFIEFWKRGLAYKKGGLVNWCPKDQTVLAN 232
Query: 181 AEV--GYVEEEGYL--------YYIKL-----PLADGS---------------------- 203
+V G+ E G +Y+K+ L D S
Sbjct: 233 EQVVNGHCERCGTAVERRNLSQWYLKITDYAEELLDFSATDMPEKVRAMQTNWIGKSVGA 292
Query: 204 --------GYIPIATTRPELMPACVAVFVHPDDERYKHL---------------VGKKVK 240
G + TTRP+ + + + P+ + K L G+K
Sbjct: 293 EVTFDTPAGPETVFTTRPDTLMGATFMVLAPEHAKVKELTTDEQRAEVEAYVAAAGRKTD 352
Query: 241 L-------------------PIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKR 281
+ PI ++PI + V +GTG++ DE+D + K+
Sbjct: 353 VERQQEGEKTGVFTGSYATHPISGHQLPIWVADYVLVTYGTGSIMAVPAHDERDFAFAKK 412
Query: 282 YNLP---VIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRH 338
++LP VI A +G ++ + PY+G +I E G+ K I + R
Sbjct: 413 FDLPIREVIRAEGSEGMGDQPSEPYSG------EGQIVNSGEFDGMPGGKASIAAIIARL 466
Query: 339 TERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVI 398
ER VAK Y RL+ DW+
Sbjct: 467 EERG---------------------------VAKAKTTY------RLR--------DWLF 485
Query: 399 SRQRVFGTPFPFWVCKNGHIIPAREEDLPV--------DPRFDKP-------PVEKCPVC 443
+RQR +GTP PF C+ + P E+ LPV P P CP C
Sbjct: 486 ARQRYWGTPIPFVHCEKCGMQPVPEDQLPVKLPENVAFTPTGQSPLKLDEEWKTTTCPCC 545
Query: 444 GAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTW 503
G E TD +D +VDSS + R+ P L G +
Sbjct: 546 GGPAERETDTMDTFVDSS---WYMYRYLSPNYDGGPFDPSKAGLLPVDLYTGGIEHAILH 602
Query: 504 AFYTIFRTFKL------TGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGAD 557
Y+ F T + T +P+ + GMV G DG KMSKS GNVV PD+++ +YGAD
Sbjct: 603 LLYSRFWTKVMRDMGLTTQSEPFARLRNQGMVLGEDGEKMSKSRGNVVDPDDLVREYGAD 662
Query: 558 ALRLWTALAPPGE-DHPFKWETVDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIELEPL 616
+R + P E P+ + ++ ++L +VWN+ F EK E +
Sbjct: 663 TVRAFLMFIAPWELGGPWDPQGINGPSKWLSRVWNV----------FFEEKVSGPEEKMQ 712
Query: 617 DRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKL 676
+ +H +K ++ ER FN I LM E+ + ++ + ++G
Sbjct: 713 GADVRFAVHSALKKVNDDFERMSFNTIISTLM-----ELTNALVKAKRSPVFGTP----- 762
Query: 677 KAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEK-SVHLLSWPEYRE 728
E L +LAP VPHI EEI+H + G+K SVH WP+ E
Sbjct: 763 ----VWEEALDIFNRMLAPVVPHIAEEIWH-----ERGQKGSVHTAQWPQVDE 806
>sp|P41257|SYI_CAMJE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|558850|gb|AAA91296.1| (U15295) isoleucyl-tRNA
synthetase [Campylobacter jejuni]
Length = 917
Score = 231 bits (583), Expect = 3e-59
Identities = 211/799 (26%), Positives = 351/799 (43%), Gaps = 109/799 (13%)
Query: 10 EIEPKWQKYWLEEKIYKYRLDEN----KPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIAR 65
E+EP+ K W E+ ++ EN K S+ + PP+ +G +H+GH L+ + I +
Sbjct: 22 ELEPQRFKKWFEQNYAYEKMKENRKNAKKSFTLHDGPPYANGHIHIGHALNKILKETIIK 81
Query: 66 YKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQ--PEEFLKKCVEWTWQAIEAMRKQ 123
+G +V F G+D HGLP E +VE + G K +E + C + + ++ R++
Sbjct: 82 THYFKGESVRFTPGWDCHGLPIEQQVEVKLGEKKKSLSKKEIREFCRQHASEFVDIQREE 141
Query: 124 FIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV 183
F +G ADWD Y TM ++AA+ ++L E KKGL+ PV+W +++LA+AEV
Sbjct: 142 FKNLGIIADWDKPYLTMKFEFEAAIYRTLCEIAKKGLLCERSKPVFWSWAAKSALAEAEV 201
Query: 184 GYVEEEGYLYYI----------KLPLADGSGYIPIATTRPELMPACVAVFVHPDD----- 228
Y ++E Y ++ KL ++ S I TT P + A A+ ++P++
Sbjct: 202 EYQDKEDYSIFVAFDLDVKACKKLGVSKASAV--IWTTTPWTLVANQAIALNPNENYVIT 259
Query: 229 ----------------------ERYKHLVGKKVKL-----PIYEREVPILADEDVDPNFG 261
E K L K+ + P+ R+ ++ E V + G
Sbjct: 260 KEGLIFASALLKSMVEKGLTSGEIQKELNAKEFEKLEAINPLNGRKSVLIMGEHVLMDGG 319
Query: 262 TGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNEN-----------AGPYAGLKVEE 310
+G V+ E D +Y + V++ +++ G +E + GL + +
Sbjct: 320 SGLVHTAPGHGEDDYYACLKYGIEVLMPVDDSGCYDETLRAKRLLPSHLLEEFIGLHIFK 379
Query: 311 ARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRV---KDFTDEI 367
A +KI E L + L K + T + P+ KQWFI + K +
Sbjct: 380 ANEKILELLGEKLLHSSKFIHSYPFCWRTHK-----PVIYRATKQWFILMDEPKLQGKTL 434
Query: 368 VKVAKE----INWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPARE 423
+ AKE +YP+ R+ E+ DW ISRQR +GTP F+ KN + +
Sbjct: 435 RECAKEQLLKTTFYPQSGVKRIGSMVENRP-DWCISRQRDWGTPIAFFRDKNTKEVIFDD 493
Query: 424 EDLP-VDPRFDKPPVE-------------KCPVCGAEIEPVTDVLDCWVDSSITPLIITR 469
E V F+K + +E V D+LD W DS T +
Sbjct: 494 ELFDFVAAIFEKHGADAWWEFEIKDLIPTNSKYNAENLEKVYDILDVWFDSGSTFNAVLN 553
Query: 470 WHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMV 529
G++ A + E G+D R W ++ + P++ I+ +G
Sbjct: 554 SGLYDAGEKRASMYLE----------GSDQHRGWFQSSLLVGTAINESTPYESILTHGFT 603
Query: 530 AGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKV 589
G+KMSKS GNV+AP+ V YG + LRLW L+ D + +K+
Sbjct: 604 TDEKGQKMSKSKGNVIAPEYVAKTYGVEILRLWILLSDYSSDLKISDNILKQVGEQYRKI 663
Query: 590 WNIYRFAERHIKDFDYEKYKDIELEP---LDRWILSRLHRIIKFATEELERYRFNLITRE 646
N RF + D KD+E++ +D+WILSR ++ K + E Y F
Sbjct: 664 RNTIRFLLANTNDL-----KDLEVKEFSFIDKWILSRASKVFKASKEAFFAYEFAKGFSL 718
Query: 647 LMTFIWHEVADDYIEMVKYRLYGDDEESKLK--AKVALYELLYNVMLLLAPFVPH-ITEE 703
L+ F+ +++ Y+++ K RLY D E ++ + A+VA+ + ++ LLA + + + E
Sbjct: 719 LLNFLSADLSGIYLDISKDRLYCDSENAQRRKSAQVAMALIAKELLNLLASNLSYSVDEA 778
Query: 704 IYHAMFKDKIGEKSVHLLS 722
+ HA K K V LS
Sbjct: 779 LEHANVLIKGDAKDVFDLS 797
>sp|P18330|SYI_PSEFL ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|577085|emb|CAA56431.1| (X80132) isoleucine-tRNA
ligase [Pseudomonas fluorescens]
Length = 943
Score = 231 bits (583), Expect = 3e-59
Identities = 201/801 (25%), Positives = 350/801 (43%), Gaps = 95/801 (11%)
Query: 3 PKKYDPNEIEPKWQKYWLEEKIY-KYR-LDENKPSYAIDTPPPFTSGTLHLGHVLSHTWI 60
P K + EP+ + W +Y K R + +++P + + PP+ +GT+H+GH L+
Sbjct: 16 PMKAGLPQREPQILQRWNSIGLYGKLREIGKDRPKFVLHDGPPYANGTIHIGHALNKILK 75
Query: 61 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFG--ITKDQPEEFLKKCVEWTWQAIE 118
D+I R K + G++ + G+D HGLP E KVE +G + D+ E C + + IE
Sbjct: 76 DMILRSKTLSGFDAPYVPGWDCHGLPIEHKVEVTYGKNLGADKTREL---CRAYATEQIE 132
Query: 119 AMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSL 178
+ +FIR+G +WD Y TM+ +A ++L E K G +++ PV WC C ++L
Sbjct: 133 GQKSEFIRLGVLGEWDNPYKTMNFKNEAGEIRALAEIVKGGFVFKGLKPVNWCFDCGSAL 192
Query: 179 AKAEVGYVEEEGYLYYIKLPLADGS--------------GYIPIATTRPELMPACVAVFV 224
A+AEV Y +++ + P+AD + I I TT P +PA A+ V
Sbjct: 193 AEAEVEYEDKKSSTIDVAFPIADDAKLAEAFGLASLAKPAAIVIWTTTPWTIPANQALNV 252
Query: 225 HPDDE-----------------------RYK-------HLVGKKVKL-----PIYEREVP 249
HP+ RY+ G ++L P Y+R P
Sbjct: 253 HPEFTYALVDVGDRLLVLAEEMVESCLARYELQGSVIATATGSALELINFRHPFYDRLSP 312
Query: 250 ILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNL---PVIIAINEDGTMNENAGPYAGL 306
+ + V+ GTG V+ D V K+Y + +I + +G + + G
Sbjct: 313 VYLADYVELGSGTGIVHCSPAYGVDDFVICKKYGMVNDDIINPVQSNGVYVPSLEFFGGQ 372
Query: 307 KVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRV-KDFTD 365
+ +A + I E L ++G L + I+H + H R P+ QWFI + K+ T
Sbjct: 373 FIFKADQPIIEKLREVGALMQTAAIQHSYM-HCWRHK--TPLIYRATAQWFIGMDKEPTS 429
Query: 366 ------EIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNG--- 416
+K ++ + P RL + DW ISRQR +G P PF++ K
Sbjct: 430 GDTLRVRSLKAIEDTKFVPSWGQARLHSMIANRP-DWCISRQRNWGVPIPFFLNKESGEL 488
Query: 417 --------HIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIIT 468
++ R E ++ F E + ++D LD W DS T
Sbjct: 489 HPRTVELMEVVAQRVEQQGIEAWFKLDAAELLGDEAPLYDKISDTLDVWFDSGTT----- 543
Query: 469 RWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGM 528
WH ++G E L +G+D R W ++ + P+++++ +G
Sbjct: 544 HWH-VLRGSHPMGH--ETGPRADLYLEGSDQHRGWFHSSLLTGCAIDNHAPYRELLTHGF 600
Query: 529 VAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQK 588
GRKMSKS NV+ P ++ GAD +RLW A + + + + ++
Sbjct: 601 TVDETGRKMSKSLKNVIEPKKINDTLGADIMRLWVASTDYSGEIAVSDQILARSADAYRR 660
Query: 589 VWNIYRFAERHIKDFD--YEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRE 646
+ N RF ++ F+ + ++ LDRW + R + + E YRF + +
Sbjct: 661 IRNTARFMLSNLTGFNPASDLLPAEDMLALDRWAVDRTLLLQRELQEHYGEYRFWNVYSK 720
Query: 647 LMTFIWHEVADDYIEMVKYRLY--GDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEI 704
+ F E+ Y++++K R Y G + +++ A+ ALY + ++ +AP + +E+
Sbjct: 721 IHNFCVQELGGFYLDIIKDRQYTTGANSKARRSAQTALYHISEALVRWIAPILAFTADEL 780
Query: 705 YHAMFKDKIGEKSVHLLSWPE 725
+ + ++ +SV L +W E
Sbjct: 781 WEYLPGER--NESVMLNTWYE 799
>pir||T27465 hypothetical protein Y87G2A.m - Caenorhabditis elegans
Length = 634
Score = 230 bits (581), Expect = 5e-59
Identities = 173/560 (30%), Positives = 258/560 (45%), Gaps = 51/560 (9%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYR-LDENKP------SYAIDTPPPFTSGTLHLGHV 54
+P Y P +E W +W +E +K +D+ P S+ + PPP +G LH+GH
Sbjct: 79 IPAAYFPGYVESGWYSWWEKEGFFKPEYIDKLNPGSNPADSFTVCIPPPNVTGNLHVGHA 138
Query: 55 LSHTWIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEK----EFGITKDQ--PEEFLKK 108
L+ T D I R+ RM G LF G D+ G+ T++ VEK E G+T+ + F ++
Sbjct: 139 LATTVEDTITRFNRMHGKRTLFNPGCDHAGIATQVVVEKRLKRERGLTRHDLGRDRFNQE 198
Query: 109 CVEWTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPV 168
W + + + QF ++G S DWD TMD AV ++ + ++ G IYR V
Sbjct: 199 VWHWKNEKGDVIYDQFRKLGASVDWDRAVFTMDPKMCRAVTEAFIRMHESGTIYRSNRLV 258
Query: 169 YWCPKCRTSLAKAEVGYVE----------------EEGYLYYIKLPLADGSGYIPIATTR 212
W R++++ EV E E G L + I ++TTR
Sbjct: 259 NWSCALRSAISDIEVDKKELTGSTLIAVPGYDKKIEFGVLNSFAYKIQGSDEEIVVSTTR 318
Query: 213 PELMPACVAVFVHPDDERYKHLVGKKVKLP-IYEREVPILADEDVDPNFGTGAVYNCTYG 271
E M V VHPDD+RYKHLVGK+ P I R +PI AD V+ FGTGAV
Sbjct: 319 IETMLGDSGVAVHPDDQRYKHLVGKQCIHPFIPTRNLPIFADSFVEMEFGTGAVKITPAH 378
Query: 272 DEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKI 331
D D R NLP I +DG +++ G ++G+K +AR + E L++ G LY+ ++
Sbjct: 379 DHNDYEVGIRQNLPFHNCITDDGLISQGCGEFSGMKRFDARTAVIEALKEKG-LYRGKED 437
Query: 332 KHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAK--EINWYPEDMFLRLKDWA 389
V+ RS + IE + K QW+++ ++ V ++ PE W
Sbjct: 438 NPMVVPTCSRSKDV--IEPILKPQWYVKCAHMAEKAVAAVANGDLQIIPEFHKATWNRWL 495
Query: 390 ESMDWDWVISRQRVFGTPFPFWVCK--NGHIIPAREEDLPVDPRFDKPPVEKC------P 441
ES DW ISRQ +G P + +G P EE+ V R ++ + K P
Sbjct: 496 ES-SRDWCISRQLWWGHRIPAYYISFADGREQPLPEENYWVSARTEQEALAKAAQKFQVP 554
Query: 442 VCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIR 501
++ DVLD W S + P + W +A K + FP A+ G DI+
Sbjct: 555 EAEILLKWDEDVLDTWFSSGMWPFAVFGWPDATKD-------MDLFFPGAVLETGHDILF 607
Query: 502 TWAFYTIFRTFKLTGKKPWK 521
W +F +LTGK P+K
Sbjct: 608 FWVARMVFMAQELTGKLPFK 627
>pir||B81309 isoleucine--tRNA ligase (EC 6.1.1.5) Cj1061c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968497|emb|CAB73317.1| (AL139077) isoleucyl-tRNA
synthetase [Campylobacter jejuni]
Length = 917
Score = 230 bits (580), Expect = 6e-59
Identities = 211/799 (26%), Positives = 351/799 (43%), Gaps = 109/799 (13%)
Query: 10 EIEPKWQKYWLEEKIYKYRLDEN----KPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIAR 65
E+EP+ K W E+ ++ EN K S+ + PP+ +G +H+GH L+ + I +
Sbjct: 22 ELEPQRFKKWFEQNYAYEKMKENRKNAKKSFTLHDGPPYANGHIHIGHALNKILKETIIK 81
Query: 66 YKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQ--PEEFLKKCVEWTWQAIEAMRKQ 123
+G +V F G+D HGLP E +VE + G K +E + C + + ++ R++
Sbjct: 82 THYFKGESVRFTPGWDCHGLPIEQQVEVKLGEKKKSLSKKEIREFCRQHASEFVDIQREE 141
Query: 124 FIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV 183
F +G ADWD Y TM ++AA+ ++L E KKGL+ PV+W +++LA+AEV
Sbjct: 142 FKDLGIIADWDKPYLTMKFEFEAAIYRTLCEIAKKGLLCERSKPVFWSWAAKSALAEAEV 201
Query: 184 GYVEEEGYLYYI----------KLPLADGSGYIPIATTRPELMPACVAVFVHPDD----- 228
Y ++E Y ++ KL ++ S I TT P + A A+ ++P++
Sbjct: 202 EYQDKEDYSIFVAFDLDVKACEKLGVSKASAV--IWTTTPWTLVANQAIALNPNENYVIT 259
Query: 229 ----------------------ERYKHLVGKKVKL-----PIYEREVPILADEDVDPNFG 261
E K L K+ + P+ R+ ++ E V + G
Sbjct: 260 KEGLIFASALLKSMVEKGLTSGEIQKELNAKEFEKLEAINPLNGRKSVLIMGEHVLMDGG 319
Query: 262 TGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNEN-----------AGPYAGLKVEE 310
+G V+ E D +Y + V++ +++ G +E + GL + +
Sbjct: 320 SGLVHTAPGHGEDDYYACLKYGIEVLMPVDDSGCYDETLRAKGLLPSHLLEEFIGLHIFK 379
Query: 311 ARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRV---KDFTDEI 367
A +KI E L + L K + T + P+ KQWFI + K +
Sbjct: 380 ANEKILELLGEKLLHSSKFIHSYPFCWRTHK-----PVIYRATKQWFILMDEPKLQGKTL 434
Query: 368 VKVAKE----INWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPARE 423
+ AKE +YP+ R+ E+ DW ISRQR +GTP F+ KN + +
Sbjct: 435 RECAKEQLLKTTFYPQSGVKRIGSMVENRP-DWCISRQRDWGTPIAFFRDKNTKEVIFDD 493
Query: 424 EDLP-VDPRFDKPPVE-------------KCPVCGAEIEPVTDVLDCWVDSSITPLIITR 469
E V F+K + +E V D+LD W DS T +
Sbjct: 494 ELFDFVAAIFEKHGADAWWEFEIKDLIPTNSKYKAENLEKVYDILDVWFDSGSTFNAVLN 553
Query: 470 WHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMV 529
G++ A + E G+D R W ++ + P++ I+ +G
Sbjct: 554 SGLYDAGEKRASMYLE----------GSDQHRGWFQSSLLVGTAINESAPYESILTHGFT 603
Query: 530 AGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKV 589
G+KMSKS GNV+A + V YG + LRLW L+ D + +K+
Sbjct: 604 TDEKGQKMSKSKGNVIASEYVAKTYGVEILRLWILLSDYSSDLKISDNILKQVGEQYRKI 663
Query: 590 WNIYRFAERHIKDFDYEKYKDIELEP---LDRWILSRLHRIIKFATEELERYRFNLITRE 646
N RF + D KD+E++ +D+WILSR ++ K + E Y F
Sbjct: 664 RNTIRFLLANTNDL-----KDLEVKEFSFIDKWILSRATKVFKASKEAFFAYEFAKGFSL 718
Query: 647 LMTFIWHEVADDYIEMVKYRLYGDDEESKLK--AKVALYELLYNVMLLLAPFVPH-ITEE 703
L+ F+ +++ Y+++ K RLY D E ++ + A+VA+ + ++ LLAP + + + E
Sbjct: 719 LLNFLSADLSGIYLDISKDRLYCDSENAQRRKSAQVAMALMAKELLNLLAPNLSYSVDEA 778
Query: 704 IYHAMFKDKIGEKSVHLLS 722
+ HA K K V LS
Sbjct: 779 LEHANVLIKGDAKDVFDLS 797
>gb|AAC41448.1| (L37104) transfer RNA-Ile synthetase [Thermotoga maritima]
Length = 505
Score = 229 bits (579), Expect = 8e-59
Identities = 158/521 (30%), Positives = 242/521 (46%), Gaps = 78/521 (14%)
Query: 81 DNHGLPTELKVEKEFG--ITKDQPEEFLKKCVEWTWQAIEAMRKQFIRIGYSADWDLEYH 138
D HGLP E +V +E G I + P E KKC E+ + ++ R++F R+G DW+ Y
Sbjct: 1 DTHGLPIEHRVSQELGEKIKEMSPAEIRKKCEEFALRFVDIQREEFKRLGVRGDWENPYI 60
Query: 139 TMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVGYVEEEGYLYYIKL- 197
T+ Y+ + ++G +YR P+YWCP+CRT+LA+AE+ Y + + Y+K
Sbjct: 61 TLKPDYEVKILDVFKTLVEQGNVYRSLKPIYWCPRCRTALAEAEIEYHDHKSPSIYVKFR 120
Query: 198 PLADGSGYIPIATTRPELMPACVAVFVHPDDE---------------------------- 229
D + +I I TT P +PA V + +HPD E
Sbjct: 121 SKEDPNFFIVIWTTTPWTLPANVGIALHPDYEYSVVKVGEEKWVIATDLLDAFSKETGID 180
Query: 230 --------RYKHLVGKKVKLPIYE-REVPILADEDVDPNFGTGAVYNCT-YGDEQDIVWQ 279
+ K L GK+ PI++ R ++ + V GTG V+ +G+E I
Sbjct: 181 CSNVVEKIKGKDLEGKEFVHPIFDDRTSRVILADYVSLETGTGCVHIAPGHGEEDYIYGH 240
Query: 280 KRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHT 339
+Y LP++ ++E+G E AG Y G+ +E+A + I EDL++ G+L I H H
Sbjct: 241 VQYGLPIVSPVDEEGRFTEEAGKYKGMFIEDANEVIIEDLKRKGILVHASSITHS-YPHC 299
Query: 340 ERSSCMAPIELLPKKQWFIRV--KDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWV 397
R C P+ +QWFI V + ++++ ++ W PE R++ E DW
Sbjct: 300 WR--CKGPVIFRATEQWFISVDHNNLRQKVLEEIDKVKWIPEWGRNRIRSMVEERP-DWC 356
Query: 398 ISRQRVFGTPFPFWVCKN-----------GHIIPAREEDLPVDPRFDK------PPVEKC 440
ISRQRV+GTP P CK H + E++ + F+K P C
Sbjct: 357 ISRQRVWGTPIPAVKCKECGEVVLDPKVIEHFMKIVEKE-GTNAWFEKEVEELIPEDFVC 415
Query: 441 PVCG-AEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDI 499
P CG E + D LD W+DS + IT E +H FP + +G+D
Sbjct: 416 PKCGKRSFEKMLDTLDVWIDSGASFEYITTKRE------------DHPFPLDMYLEGSDQ 463
Query: 500 IRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKS 540
R W +IF G P+K+++ +G + GRKMSKS
Sbjct: 464 HRGWFHSSIFLAVAKRGSAPYKEVLTHGFIKDEQGRKMSKS 504
>sp|P56456|SYI_HELPY ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437556|pir||F64697 isoleucine--tRNA ligase (EC
6.1.1.5) - Helicobacter pylori (strain 26695)
>gi|2314596|gb|AAD08464.1| (AE000642) isoleucyl-tRNA
synthetase (ileS) [Helicobacter pylori 26695]
Length = 920
Score = 228 bits (574), Expect = 3e-58
Identities = 200/778 (25%), Positives = 337/778 (42%), Gaps = 106/778 (13%)
Query: 12 EPKWQKYWLEEKIYK--YRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRM 69
EPK W E++ +K +N + + PP+ +G LHLGH L+ DI+ + +
Sbjct: 25 EPKTYAKWQEQQAFKRMQARKDNHGDFTLHDGPPYANGHLHLGHALNKILKDIVVKREYF 84
Query: 70 RGYNVLFPQGFDNHGLPTELKV----EKEFGITKDQPEEFLKKCVEWTWQAIEAMRKQFI 125
+G + + G+D HGLP E ++ EKE + + P F +KC + + +E + +F+
Sbjct: 85 KGKKIYYTPGWDCHGLPIEQQILERLEKE-KTSLENPTLFREKCRDHAKKFLEIQKNEFL 143
Query: 126 RIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVGY 185
++G D++ Y TMD ++A++ ++L+E KKGL+ P+YW C ++LA+AEV Y
Sbjct: 144 QLGVLGDFEDPYKTMDFKFEASIYRALVEVAKKGLLKERHKPIYWSYACESALAEAEVEY 203
Query: 186 VEEEGYLYYIKLPLADGS--------GYIPIATTRPELMPACVAVFVHPDD----ERYKH 233
++ ++ L S + I TT P + A VA+ + D + +
Sbjct: 204 KMKKSPSIFVAFGLKKESLEKLKVKKASLVIWTTTPWTLYANVAIALKKDAVYALTQKGY 263
Query: 234 LVGKKV--KL--------------------------PIYEREVPILADEDVDPNFGTGAV 265
LV K + KL P+ +R+ + E V GTGAV
Sbjct: 264 LVAKALHEKLAALGVVDNEITHEFNSNDLEYLVATNPLNQRDSLVALGEHVGLEDGTGAV 323
Query: 266 YNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENA-------GPYAGLKVEEARKKIAED 318
+ E+D RYNL V+++++E G +E Y G V +A+K+I E
Sbjct: 324 HTAPGHGEEDYYLGLRYNLEVLMSVDEKGCYDEGIIHNQLLDESYLGEHVFKAQKRIIEQ 383
Query: 319 LEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRV-----------KDFTDEI 367
L LL +++I+H H R+ P+ QWFI + K +
Sbjct: 384 LGDSLLL--EQEIEHS-YPHCWRTH--KPVIYRATTQWFILMDEPFIQNDGSQKTLREVA 438
Query: 368 VKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPAREEDL- 426
+ +++ + P RLK E+ DW +SRQR +G P F++ K + P E ++
Sbjct: 439 LDAIEKVEFVPSSGKNRLKTMIENRP-DWCLSRQRKWGVPLAFFIDKRTN-KPCFESEVL 496
Query: 427 -PVDPRFDKPPVEKCPVC----------------GAEIEPVTDVLDCWVDSSITPLIITR 469
V F+K + C V E + +LD W DS T +
Sbjct: 497 EHVANLFEK---KGCDVWWEYSVKDLLPPSYQEDAKHYEKIMHILDVWFDSGSTFKAVLE 553
Query: 470 WHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMV 529
+ KG P+ + +G+D R W ++ L + P+K ++ +G +
Sbjct: 554 DYHGEKGQS----------PSDVILEGSDQHRGWFQSSLLIGCVLNNQAPFKKVITHGFI 603
Query: 530 AGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKV 589
G KMSKS GNVV+ D+++ +G+D +RLW A D + +K
Sbjct: 604 VDEKGEKMSKSKGNVVSLDKLLKTHGSDVVRLWVAFNDYQNDLRVSQTFFTQTEQHYKKF 663
Query: 590 WNIYRFAERHIKDFDYEKY-KDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELM 648
N +F + D D + + PLD ++L L I E + F LM
Sbjct: 664 RNTLKFLLANFSDMDLKNLERPHNFSPLDHFMLETLETISAGVNSAFEEHDFVKGLNILM 723
Query: 649 TFIWHEVADDYIEMVKYRLYGD--DEESKLKAKVALYELLYNVMLLLAPFVPHITEEI 704
F+ +E++ Y++ K LY D + E + ++ L + LAP + H EE+
Sbjct: 724 AFVTNELSGIYLDACKDSLYCDSKNNEKRQAIQMVLLATASKLCYFLAPILTHTIEEV 781
>pir||E75407 isoleucyl-tRNA synthetase - Deinococcus radiodurans (strain R1)
>gi|6459088|gb|AAF10907.1|AE001980_2 (AE001980)
isoleucyl-tRNA synthetase [Deinococcus radiodurans]
Length = 1078
Score = 224 bits (564), Expect = 5e-57
Identities = 177/646 (27%), Positives = 302/646 (46%), Gaps = 49/646 (7%)
Query: 250 ILAD--EDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLK 307
++AD DVD G+G + +D+ + Y +P++ +++ G + G
Sbjct: 346 VMADFVSDVD---GSGVAHEAPAYGAEDLEVARAYGVPLMFGVDDHGILQVTHEQ--GKF 400
Query: 308 VEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEI 367
++A K + D++ GL++ +KHR H PI KK W+IR E+
Sbjct: 401 FKDADKGLIADMKARGLMFWAGTLKHRYPFHDRTGD---PILYFAKKGWYIRTSQVAGEM 457
Query: 368 VKVAKEINWYPEDM-FLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGH--IIPAREE 424
+ ++INW P ++ R +W E + DW ISR+R +GTP PFW ++G +I + E
Sbjct: 458 LAQNEKINWVPGNIKHGRFGNWLEG-NVDWAISRERYWGTPLPFWQSESGQLRVIGSVAE 516
Query: 425 -------DLPVDPRFDKPPVEKCPVC--GAEIEPVTDVLDCWVDSSITP-----LIITRW 470
DL D +P ++ G E V +VLD W DS P L++
Sbjct: 517 LSELAGRDLS-DLDLHRPYIDDITFTLDGEEYRRVPEVLDVWFDSGSMPYAQWGLLLNEQ 575
Query: 471 HEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKP-WKDIVINGMV 529
EA++G E+ F ++P + D R W FY++ + +P +K+++ G +
Sbjct: 576 GEAVRGAEQ----FAKHYPADYICEAIDQTRGW-FYSLHAISTMLYDQPAYKNVICLGHI 630
Query: 530 AGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALA-PPGEDHPFKWETV-DYNFRFLQ 587
G KMSKS GNVVAP + +YGAD++R + +A PG+ F V + ++
Sbjct: 631 VDEKGLKMSKSKGNVVAPLPLFDQYGADSVRWYMFMASDPGDQKRFSERLVAEAQRSYVN 690
Query: 588 KVWNIYRF--AERHIKDFDYEKYKDIELEP-LDRWILSRLHRIIKFATEELERYRFNLIT 644
+WN+Y F ++ D + P +DRW+L+RL ++ T LE Y
Sbjct: 691 TLWNVYSFFVLYANLDQPDLAAAPAVAERPEMDRWLLARLEETVRDVTAALESYDARSGG 750
Query: 645 RELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEI 704
R L F+ ++++ Y+ + R +G+ A L+E L V L APF P + + +
Sbjct: 751 RALEGFV-DDLSNWYVRRSRSRFWGEGGTVDTAAYATLHEALLVVSQLTAPFTPFLADAL 809
Query: 705 YHAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKL 764
Y + + E SVHL WP R +R+D K KVV R + +H + L
Sbjct: 810 YRNLSGE---ESSVHLTPWPTVRAERLDRKLTADMAAVMKVVELGRAVRGAHNLKTRQPL 866
Query: 765 EHVAIYAL--ESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYG 822
V + A E+ D LK + I +N++ + +G+ L + ++PN +G +YG
Sbjct: 867 AGVQVRAASPEALDALKRSQTQIMEELNVKAVTFLEGDTDLVQ--YSLRPNLPVVGKQYG 924
Query: 823 KLVPRIVEHL-KNNAESIAREIKENGKVEFEIDGEKVELTKEDVMI 867
K +P + + L + +A ++A ++ + DG +LT V++
Sbjct: 925 KQLPVLKKALTEADARAVATAVQAGQGFSVQADGVTFDLTPGSVLV 970
Score = 93.6 bits (229), Expect = 9e-18
Identities = 59/212 (27%), Positives = 108/212 (50%), Gaps = 15/212 (7%)
Query: 3 PKKYDPN--EIEPKWQKYWLEEKIYKYRLDENKPS--YAIDTPPPFTSGTLHLGHVLSHT 58
P PN ++E + W +E++++ P+ + PP +G L HVL+ +
Sbjct: 8 PVPTQPNFRQLEADILQKWKDEQVFEQTQTRPAPAGEFVFYEGPPTANGKPALHHVLARS 67
Query: 59 WIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEF-------GITKDQPEEFLKKCVE 111
+ D+ R+K M+G++V G+D HGLP E+ VEK+ G ++++ EEF + C
Sbjct: 68 FKDLFPRFKVMQGHHVTRKGGWDTHGLPVEISVEKKLGWLGRNHGASREELEEFNRLCRT 127
Query: 112 WTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWC 171
W+ I+ + R+GY D Y T + Y +V L ++KGL+ ++ V
Sbjct: 128 SVWETIQDWNELTERMGYWLDLGDPYITYQNSYVESVWNLLRRLHEKGLVAQDYKVVPLS 187
Query: 172 PKCRTSLAKAEVGYVEE----EGYLYYIKLPL 199
P+ ++L++AE+G V+ + Y++LP+
Sbjct: 188 PRISSTLSRAELGEVDSYRMVDDPSVYVRLPI 219
>sp|Q10765|SYI_MYCTU ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437561|pir||E70760 probable ileS protein -
Mycobacterium tuberculosis (strain H37RV)
>gi|1403506|emb|CAA98326.1| (Z74020) ileS [Mycobacterium
tuberculosis]
Length = 1041
Score = 222 bits (560), Expect = 1e-56
Identities = 234/918 (25%), Positives = 379/918 (40%), Gaps = 140/918 (15%)
Query: 18 YWLEEKIYKYRLD--ENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRMRGYNVL 75
YW + ++ + + P Y PPF +G H GH+L+ DI+ RY+ MRGY V
Sbjct: 26 YWSRDDTFRASIARRDGAPEYVFYDGPPFANGLPHYGHLLTGYVKDIVPRYRTMRGYKVE 85
Query: 76 FPQGFDNHGLPTELKVEKEFGIT-KDQPEE-----FLKKC----VEWT--WQAIEAMRKQ 123
G+D HGLP EL+VE++ GIT K Q E F C + +T WQA + +
Sbjct: 86 RRFGWDTHGLPAELEVERQLGITDKSQIEAMGIAAFNDACRASVLRYTDEWQAYVTRQAR 145
Query: 124 FIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV 183
++ D+D +Y T+D Y +V + + + KGL Y + +C + T L+ E+
Sbjct: 146 WV------DFDNDYKTLDLAYMESVIWAFKQLWDKGLAYEGYRVLPYCWRDETPLSNHEL 199
Query: 184 G-----YVEEEGYLYYIKLPLADGS-------GYIPIATTRPELMPACVAVFVHPD---- 227
Y + + + G Y+ + TT P +P+ +AV V PD
Sbjct: 200 RMDDDVYQSRQDPAVTVGFKVVGGQPDNGLDGAYLLVWTTTPWTLPSNLAVAVSPDITYV 259
Query: 228 -----DERYKHLVGKKVKLPIYEREV---------------------------------- 248
D R+ V + +L Y RE+
Sbjct: 260 QVQAGDRRF---VLAEARLAAYARELGEEPVVLGTYRGAELLGTRYLPPFAYFMDWPNAF 316
Query: 249 PILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKV 308
+LA + V + GTG V+ E D+V + + + ++ G + Y G V
Sbjct: 317 QVLAGDFVTTDDGTGIVHMAPAYGEDDMVVAEAVGIAPVTPVDSKGRFDVTVADYQGQHV 376
Query: 309 EEARKKIAEDLEKMG---LLYKKEKIKHRVLRHTERSS--CMAPIELLPKKQWFIRVKDF 363
+A +I DL+ + I+H H C P+ WF+RV DF
Sbjct: 377 FDANAQIVRDLKTQSGPAAVNGPVLIRHETYEHPYPHCWRCRNPLIYRSVSSWFVRVTDF 436
Query: 364 TDEIVKVAKEINWYPEDMFLRLKD-----WAESMDWDWVISRQRVFGTPFPFWVCKNGHI 418
D +V++ ++I WYPE +KD W + DW ISR R +GTP P W +
Sbjct: 437 RDRMVELNQQITWYPE----HVKDGQFGKWLQGAR-DWSISRNRYWGTPIPVWKSDDPAY 491
Query: 419 --------IPAREEDLPVDP-RFDKPPVEKC-------PVCGAEIEPVTDVLDCWVDSSI 462
+ E D V P +P +++ P + + + DVLD W DS
Sbjct: 492 PRIDVYGSLDELERDFGVRPANLHRPYIDELTRPNPDDPTGRSTMRRIPDVLDVWFDSGS 551
Query: 463 TPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTI-FRTFKLTGKKPWK 521
P + + E WF+ ++P + R W FYT+ L + +K
Sbjct: 552 MP------YAQVHYPFENLDWFQGHYPGDFIVEYIGQTRGW-FYTLHVLATALFDRPAFK 604
Query: 522 DIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPP----GEDHPFKWE 577
V +G+V G DG+KMSKS N EV + G+DA+R W +A P G +
Sbjct: 605 TCVAHGIVLGFDGQKMSKSLRNYPDVTEVFDRDGSDAMR-WFLMASPILRGGNLIVTEQG 663
Query: 578 TVDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELER 637
D + L +WN Y F + + + + LDR+IL++L + +E +E
Sbjct: 664 IRDGVRQVLLPLWNTYSFLALYAPKVGTWRVDSVHV--LDRYILAKLAVLRDDLSESMEV 721
Query: 638 YRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFV 697
Y L F + + Y+ + R + +D + A L+ +L L AP +
Sbjct: 722 YDIPGACEHLRQFT-EALTNWYVRRSRSRFWAEDAD----AIDTLHTVLEVTTRLAAPLL 776
Query: 698 PHITEEIYHAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGEL--ARKVVSEMRKYKNS 755
P ITE I+ + + E+SVHL WP D + A+ + + R V S + +
Sbjct: 777 PLITEIIWRGLTR----ERSVHLTDWP--APDLLPSDADLVAAMDQVRDVCSAASSLRKA 830
Query: 756 HGMPLNAKLEHVAIYALESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYK 815
+ + L + I A+E+ L+ I +N++++E+ E+ N +
Sbjct: 831 KKLRVRLPLPKL-IVAVENPQLLRPFVDLIGDELNVKQVELTDAIDTYGR--FELTVNAR 887
Query: 816 RIGPRYGKLVPRIVEHLK 833
GPR GK V ++ +K
Sbjct: 888 VAGPRLGKDVQAAIKAVK 905
>pir||A64379 isoleucine--tRNA ligase (EC 6.1.1.5) - Methanococcus jannaschii
Length = 942
Score = 222 bits (559), Expect = 2e-56
Identities = 257/995 (25%), Positives = 424/995 (41%), Gaps = 199/995 (20%)
Query: 7 DPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARY 66
D EIE KWQK W E KI++ D+ + + I P+ +G LH GH+ + T +++AR+
Sbjct: 6 DFKEIEKKWQKRWEEAKIFEANPDDRE-KFFITAAFPYLNGVLHAGHLRTFTIPEVVARF 64
Query: 67 KRMRGYNVLFPQGFDNHGLP----TELKVEKE----------FGITKDQPEEFL--KKCV 110
+RM+ NVL+ G+ G P EL ++ GI K++ E +K V
Sbjct: 65 QRMKNKNVLWTFGYHVTGTPILGLAELIKNRDEKTIWAYTELHGIPKEELLELTTPEKIV 124
Query: 111 EWTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYW 170
E+ + E + F R+G+S DW + T D + ++ + +KGLI + HPV +
Sbjct: 125 EYFSKKAE---EAFKRMGFSLDWRRNFKTDDKVFNKFIEWQFHKLKEKGLIVKGSHPVRY 181
Query: 171 CPKCRTSLAKAEVGYVEEEGYLYYIKLPLADGSGYI-PIATTRPELMPACVAVFVHPD-- 227
CP+C + ++ E + YI + G I P+AT RPE + V+V+P+
Sbjct: 182 CPRCDNPVEDHDILVGENATLVEYILIKFTTEDGCIMPMATLRPETVFGVTNVWVNPEAT 241
Query: 228 ------------------------------DERYKH---------------LVGKKVKLP 242
E+ KH L+ KKVK P
Sbjct: 242 YVKAKVYLEKETENGIXLIENGIWIMAKECAEKLKHQDRKIEIIEEFKGEQLINKKVKNP 301
Query: 243 IYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNL-------PVI-------- 287
+ +EVPIL + V N GTG V + D + + L P+I
Sbjct: 302 VTGKEVPILPAKFVKTNIGTGCVMSVPAHAPYDYIALRDLGLVDEIGLIPLINVPGYGKY 361
Query: 288 ----------IAINED------------------GTMNENAGPYAGLKVEEARKKIAEDL 319
I E+ G +NEN Y G+ V E + K+ +DL
Sbjct: 362 PAKEIVEKMGIKSQEEEDKLEEATKKIYKDEFHKGVLNENCLDYEGIPVREIKDKLTKDL 421
Query: 320 EKMGLLYKKEKIKHRVLRHTERSSCMAP-IELLPKKQWFIRVKD--FTDEIVKVAKEINW 376
GL +I + C P I + K QWFI+ D + + K ++ +
Sbjct: 422 IDKGL----AEIMYEFSEEKVICRCGTPCIVKMVKGQWFIKYSDEKWKELAHKCIDKMRF 477
Query: 377 YPEDMFLRLKDWAESMDW--DWVISRQRVFGTPFPF---WVCK---NGHIIPAREEDLP- 427
PE++ + + E +DW D R+R GT FPF WV + + I PA
Sbjct: 478 IPENL---RQVFHEKIDWMKDKACVRRRGLGTKFPFEEGWVIESLSDSTIYPAYYTVAKY 534
Query: 428 VDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHN 487
++ KP + DV ++ I II E +K F +
Sbjct: 535 INQHNIKPEQLTLELFDYVFLGKGDVDKIAKETGIPKDII----------EGMRKEFIYY 584
Query: 488 FPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPW-KDIVINGMVAGPDGRKMSKSYGNVVA 546
+P R D+I + IF + ++ W + IV+NG V +G+K+SKS G V+
Sbjct: 585 YPVDWRCSAKDLIPNHLTFYIFNHVAIFPEEFWPRGIVVNGYVT-IEGKKLSKSKGPVLP 643
Query: 547 PDEVIPKYGADALRLW-TALAPPGEDHPFKWETVDYNFRFLQKVWNIYR-FAERHIKDFD 604
EV K+GAD R + T A +D K++ ++ + L++++ + AER + +
Sbjct: 644 VLEVAEKFGADVGRFYITTCAELPQDADIKFKEMENTKKVLERLYLFAKEIAERRGETGE 703
Query: 605 YEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVK 664
E +D+W+LSRL++ +K E +E + + +++ DD +
Sbjct: 704 -------EFSYIDKWLLSRLYKAVKQYDEYMENFEL-----RKAGILLYQLLDD---LKW 748
Query: 665 YRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWP 724
YR G + L+ E L ++ L+ PF PH+ EE++ + K E V L +P
Sbjct: 749 YRRRGGNNIRVLE------EFLEVIIKLMMPFTPHLCEEMWEILGK----EGFVSLAKFP 798
Query: 725 EYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALES----YDDLKL 780
E +E+ I+++ EK E + V+ ++++ N AK++ IY + Y+ LK+
Sbjct: 799 EVKEEFINDEIEKGEEYLKAVMEDIKEIINV------AKVQPKRIYLYTADDWKYEILKI 852
Query: 781 IEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHL-KNNAESI 839
I+++ T+ E + I P+ +YGK +P++V L K NAE I
Sbjct: 853 IKENEGKTIK-ELMPIIMKNPEFR---------------KYGKEIPKLVNQLIKLNAEII 896
Query: 840 AR-EIKENGK--VEFEIDGEKVELTKEDVMIKKEV 871
E+ EN K ++ E+ E + + ED KK V
Sbjct: 897 NEVEVLENAKEFLKKEVGVEDIIINGEDKANKKRV 931
>sp|Q58050|SYL_METJA LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|2826301|gb|AAB98628.1| (U67511) leucyl-tRNA
synthetase (leuS) [Methanococcus jannaschii]
Length = 942
Score = 222 bits (559), Expect = 2e-56
Identities = 257/995 (25%), Positives = 424/995 (41%), Gaps = 199/995 (20%)
Query: 7 DPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARY 66
D EIE KWQK W E KI++ D+ + + I P+ +G LH GH+ + T +++AR+
Sbjct: 6 DFKEIEKKWQKRWEEAKIFEANPDDRE-KFFITAAFPYLNGVLHAGHLRTFTIPEVVARF 64
Query: 67 KRMRGYNVLFPQGFDNHGLP----TELKVEKE----------FGITKDQPEEFL--KKCV 110
+RM+ NVL+ G+ G P EL ++ GI K++ E +K V
Sbjct: 65 QRMKNKNVLWTFGYHVTGTPILGLAELIKNRDEKTIWAYTELHGIPKEELLELTTPEKIV 124
Query: 111 EWTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYW 170
E+ + E + F R+G+S DW + T D + ++ + +KGLI + HPV +
Sbjct: 125 EYFSKKAE---EAFKRMGFSLDWRRNFKTDDKVFNKFIEWQFHKLKEKGLIVKGSHPVRY 181
Query: 171 CPKCRTSLAKAEVGYVEEEGYLYYIKLPLADGSGYI-PIATTRPELMPACVAVFVHPD-- 227
CP+C + ++ E + YI + G I P+AT RPE + V+V+P+
Sbjct: 182 CPRCDNPVEDHDILVGENATLVEYILIKFTTEDGCIMPMATLRPETVFGVTNVWVNPEAT 241
Query: 228 ------------------------------DERYKH---------------LVGKKVKLP 242
E+ KH L+ KKVK P
Sbjct: 242 YVKAKVYLEKETENGIELIENGIWIMAKECAEKLKHQDRKIEIIEEFKGEQLINKKVKNP 301
Query: 243 IYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNL-------PVI-------- 287
+ +EVPIL + V N GTG V + D + + L P+I
Sbjct: 302 VTGKEVPILPAKFVKTNIGTGCVMSVPAHAPYDYIALRDLGLVDEIGLIPLINVPGYGKY 361
Query: 288 ----------IAINED------------------GTMNENAGPYAGLKVEEARKKIAEDL 319
I E+ G +NEN Y G+ V E + K+ +DL
Sbjct: 362 PAKEIVEKMGIKSQEEEDKLEEATKKIYKDEFHKGVLNENCLDYEGIPVREIKDKLTKDL 421
Query: 320 EKMGLLYKKEKIKHRVLRHTERSSCMAP-IELLPKKQWFIRVKD--FTDEIVKVAKEINW 376
GL +I + C P I + K QWFI+ D + + K ++ +
Sbjct: 422 IDKGL----AEIMYEFSEEKVICRCGTPCIVKMVKGQWFIKYSDEKWKELAHKCIDKMRF 477
Query: 377 YPEDMFLRLKDWAESMDW--DWVISRQRVFGTPFPF---WVCK---NGHIIPAREEDLP- 427
PE++ + + E +DW D R+R GT FPF WV + + I PA
Sbjct: 478 IPENL---RQVFHEKIDWMKDKACVRRRGLGTKFPFEEGWVIESLSDSTIYPAYYTVAKY 534
Query: 428 VDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHN 487
++ KP + DV ++ I II E +K F +
Sbjct: 535 INQHNIKPEQLTLELFDYVFLGKGDVDKIAKETGIPKDII----------EGMRKEFIYY 584
Query: 488 FPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPW-KDIVINGMVAGPDGRKMSKSYGNVVA 546
+P R D+I + IF + ++ W + IV+NG V +G+K+SKS G V+
Sbjct: 585 YPVDWRCSAKDLIPNHLTFYIFNHVAIFPEEFWPRGIVVNGYVT-IEGKKLSKSKGPVLP 643
Query: 547 PDEVIPKYGADALRLW-TALAPPGEDHPFKWETVDYNFRFLQKVWNIYR-FAERHIKDFD 604
EV K+GAD R + T A +D K++ ++ + L++++ + AER + +
Sbjct: 644 VLEVAEKFGADVGRFYITTCAELPQDADIKFKEMENTKKVLERLYLFAKEIAERRGETGE 703
Query: 605 YEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVK 664
E +D+W+LSRL++ +K E +E + + +++ DD +
Sbjct: 704 -------EFSYIDKWLLSRLYKAVKQYDEYMENFEL-----RKAGILLYQLLDD---LKW 748
Query: 665 YRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWP 724
YR G + L+ E L ++ L+ PF PH+ EE++ + K E V L +P
Sbjct: 749 YRRRGGNNIRVLE------EFLEVIIKLMMPFTPHLCEEMWEILGK----EGFVSLAKFP 798
Query: 725 EYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALES----YDDLKL 780
E +E+ I+++ EK E + V+ ++++ N AK++ IY + Y+ LK+
Sbjct: 799 EVKEEFINDEIEKGEEYLKAVMEDIKEIINV------AKVQPKRIYLYTADDWKYEILKI 852
Query: 781 IEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHL-KNNAESI 839
I+++ T+ E + I P+ +YGK +P++V L K NAE I
Sbjct: 853 IKENEGKTIK-ELMPIIMKNPEFR---------------KYGKEIPKLVNQLIKLNAEII 896
Query: 840 AR-EIKENGK--VEFEIDGEKVELTKEDVMIKKEV 871
E+ EN K ++ E+ E + + ED KK V
Sbjct: 897 NEVEVLENAKEFLKKEVGVEDIIINGEDKANKKRV 931
>sp|Q9ZJJ1|SYI_HELPJ ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437555|pir||F71823 isoleucine--tRNA ligase (EC
6.1.1.5) - Helicobacter pylori (strain J99)
>gi|4155922|gb|AAD06890.1| (AE001554) ISOLEUCYL-TRNA
SYNTHETASE [Helicobacter pylori J99]
Length = 920
Score = 220 bits (556), Expect = 4e-56
Identities = 192/774 (24%), Positives = 333/774 (42%), Gaps = 98/774 (12%)
Query: 12 EPKWQKYWLEEKIYKYRLD--ENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRM 69
EPK W E++ +K + +N + + PP+ +G LHLGH L+ DI+ + +
Sbjct: 25 EPKTYAKWQEQQAFKRMQNRKDNHGDFTLHDGPPYANGHLHLGHALNKILKDIVIKREYF 84
Query: 70 RGYNVLFPQGFDNHGLPTELKVEKEFGITK---DQPEEFLKKCVEWTWQAIEAMRKQFIR 126
+G + + G+D HGLP E ++ ++ K + P F +KC + + +E + +F++
Sbjct: 85 KGKKIYYTPGWDCHGLPIEQQILEQLEKEKTSLENPTLFREKCRDHAKKFLEIQKNEFLQ 144
Query: 127 IGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVGYV 186
+G D++ Y TMD ++A++ ++L+ KKGL+ P+YW C ++LA+AEV Y
Sbjct: 145 LGVLGDFEDPYKTMDFKFEASIYRALVGVAKKGLLKERHKPIYWSYACESALAEAEVEYK 204
Query: 187 EEEGYLYYIKLPLADGS--------GYIPIATTRPELMPACVAVFVHPDD----ERYKHL 234
++ ++ L + I TT P + A VA+ + D + +L
Sbjct: 205 MKKSPSIFVAFDLKKEGLEKLKVKKASLVIWTTTPWTLYANVAIALKKDAVYALTQKGYL 264
Query: 235 VGKKV--KL--------------------------PIYEREVPILADEDVDPNFGTGAVY 266
V K + KL P+ +R+ ++ + V GTGAV+
Sbjct: 265 VAKALHEKLAALGVVDNAITHEFNSNDLEYLVATNPLNQRDSLVVLGDHVSLEDGTGAVH 324
Query: 267 NCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENA-------GPYAGLKVEEARKKIAEDL 319
E+D +Y+L V+++++E G +E Y G + +A+K+I E L
Sbjct: 325 TAPGHGEEDYYLGLKYHLEVLMSVDEKGCYDEGIIHNQLLDKSYLGEHIFKAQKRIIEQL 384
Query: 320 EKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRV-----------KDFTDEIV 368
LL + +I+H H R+ P+ QWFI + K + +
Sbjct: 385 GDSLLL--EREIEHS-YPHCWRTH--KPVIYRATTQWFILMDEPFIQNDGSQKTLREVAL 439
Query: 369 KVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKN-----------GH 417
+++ + P RLK E+ DW +SRQR +G P F++ K H
Sbjct: 440 DAIEKVEFVPSSGKNRLKTMIENRP-DWCLSRQRKWGVPLAFFIDKRTNKPCFESEVLEH 498
Query: 418 IIPAREEDLPVDPRFDKPPVEKCPVC----GAEIEPVTDVLDCWVDSSITPLIITRWHEA 473
+ EE D ++ + P E V +LD W DS T + +
Sbjct: 499 VANLFEEK-GCDVWWEYNIKDLLPPSYQDNAKHYEKVMHILDVWFDSGSTFKAVLEDYHG 557
Query: 474 IKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPD 533
KG P+ + +G+D R W ++ L + P+K ++ +G +
Sbjct: 558 EKGQS----------PSDVVLEGSDQHRGWFQSSLLIGCVLNNQAPFKKVITHGFIVDEK 607
Query: 534 GRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIY 593
G KMSKS GNVV+ D ++ K+G+D +RLW A D + +K N
Sbjct: 608 GEKMSKSKGNVVSLDNLLKKHGSDVVRLWVAFNDYQNDLRVSQTFFIQTEQHYKKFRNTL 667
Query: 594 RFAERHIKDFDYEKY-KDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIW 652
+F + D D + + + PLD +IL L I E + LM F+
Sbjct: 668 KFLLANFSDMDLKNLERPHDFSPLDHFILEALETISAGVNSAFEEHDLVKGLNILMAFVT 727
Query: 653 HEVADDYIEMVKYRLYGD--DEESKLKAKVALYELLYNVMLLLAPFVPHITEEI 704
+E++ Y++ K LY D + E + ++ L + + LAP + H EE+
Sbjct: 728 NELSGIYLDACKDSLYCDSKNNEKRQAIQMVLLAVASQLCYFLAPILTHTIEEV 781
>gi|11499997 leucyl-tRNA synthetase (leuS) [Archaeoglobus fulgidus]
>gi|3122899|sp|O30250|SYL_ARCFU LEUCYL-TRNA SYNTHETASE
(LEUCINE--TRNA LIGASE) (LEURS) >gi|7437642|pir||F69552
leucyl-tRNA synthetase (leuS) homolog - Archaeoglobus
fulgidus >gi|2650668|gb|AAB91241.1| (AE001108)
leucyl-tRNA synthetase (leuS) [Archaeoglobus fulgidus]
Length = 932
Score = 215 bits (543), Expect = 1e-54
Identities = 223/870 (25%), Positives = 383/870 (43%), Gaps = 185/870 (21%)
Query: 11 IEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRMR 70
IE KWQK W +++I++ +E K + + P P+ +G LH GH + T D ARY RM+
Sbjct: 7 IEEKWQKAWEKDRIFESDPNE-KEKFFLTIPYPYLNGNLHAGHTRTFTIGDAFARYMRMK 65
Query: 71 GYNVLFPQGFDNHGLP----TELKVEKE------FGITKDQPEEFL------KKCVEW-T 113
GYNVLFP GF G P EL +++ + D P E L +K VE+ +
Sbjct: 66 GYNVLFPLGFHVTGTPIIGLAELIAKRDERTIEVYTKYHDVPLEDLLQLTTPEKIVEYFS 125
Query: 114 WQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPK 173
+A++A++ IGYS DW + T D+ Y+ ++ + + GLI + HPV +CP
Sbjct: 126 REALQALKS----IGYSIDWRRVFTTTDEEYQRFIEWQYWKLKELGLIVKGTHPVRYCPH 181
Query: 174 CRTSLAKAEVGYVEEEGYLYY--IKLPLADGSGYIPIATTRPELMPACVAVFVHP----- 226
+ + ++ EE + + IK L DG P AT RPE + ++V P
Sbjct: 182 DQNPVEDHDLLAGEEATIVEFTVIKFRLEDGDLIFPCATLRPETVFGVTNIWVKPTTYVI 241
Query: 227 ----------DDERYKHLV------------------GKKVKLPIYEREVPILADEDVDP 258
E Y+ L GK V +P+ R+VPIL E VD
Sbjct: 242 AEVDGEKWFVSKEAYEKLTYTEKKVRLLEEVDASQFFGKYVIVPLVNRKVPILPAEFVDT 301
Query: 259 NFGTGAVYN----------------------CTYGDEQDIVWQKR---------YNLPVI 287
+ TG V + YG ++ +V + +P
Sbjct: 302 DNATGVVMSVPAHAPFDLAAIEDLKRDEETLAKYGIDKSVVESIKPIVLIKTDIEGVPAE 361
Query: 288 IAINEDGT-------------------------MNENAGPYAGLKVEEARKKIAEDLEKM 322
I E G M +N YAG+KV EA++++ EDL K+
Sbjct: 362 KLIRELGVKSQKDKELLDKATKTLYKKEYHTGIMLDNTMNYAGMKVSEAKERVHEDLVKL 421
Query: 323 GLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRV--KDFTDEIVKVAKEINWYPED 380
GL + + + + C+ + + QWF+ +++ ++++ +++ P+
Sbjct: 422 GLGDVFYEFSEKPVICRCGTKCVVKV---VRDQWFLNYSNREWKEKVLNHLEKMRIIPD- 477
Query: 381 MFLRLKDWAESMDW--DWVISRQRVFGTPFPF---WVCKN--------GHIIPAREEDLP 427
+++ ++W D +R++ GT P+ W+ ++ + I A+ +
Sbjct: 478 --YYKEEFRNKIEWLRDKACARRKGLGTRIPWDKEWLIESLSDSTIYMAYYILAKYINAG 535
Query: 428 VDPRFDKPP--VEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFE 485
+ + P ++ + E+ V + S ++ +I + I+ D FE
Sbjct: 536 LLKAENMTPEFLDYVLLGKGEVGKVAEA------SKLSVELI----QQIRDD------FE 579
Query: 486 HNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPW-KDIVINGMVAGPDGRKMSKSYGNV 544
+ +P LR G D++ + +F + W + I +NG V+ +G+KMSKS G +
Sbjct: 580 YWYPVDLRSSGKDLVANHLLFYLFHHVAIFPPDKWPRAIAVNGYVS-LEGKKMSKSKGPL 638
Query: 545 VAPDEVIPKYGADALRLWTA-LAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDF 603
+ + +YGAD RL+ A D +K V+ L++ +N+ + E ++K+
Sbjct: 639 LTMKRAVQQYGADVTRLYILHAAEYDSDADWKSREVEGLANHLRRFYNLVK--ENYLKEV 696
Query: 604 DYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMV 663
EL LDRW++SR+ R IK E ++ NL TR + + E+ +D V
Sbjct: 697 G-------ELTTLDRWLVSRMQRAIKEVREAMD----NLQTRRAVNAAFFELMND----V 741
Query: 664 KYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSW 723
++ L E L +L + + LLAPF PHI EE++H + V L S+
Sbjct: 742 RWYLRRGGEN--------LAIILDDWIKLLAPFAPHICEELWHLKH-----DSYVSLESY 788
Query: 724 PEYREDRIDEKAEKLGELARKVVSEMRKYK 753
PEY E R+DE+AE++ E R +V ++++ K
Sbjct: 789 PEYDETRVDEEAERIEEYLRNLVEDIQEIK 818
>sp|P75258|SYI_MYCPN ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|2146323|pir||S73648 isoleucine--tRNA ligase (EC
6.1.1.5) ileS - Mycoplasma pneumoniae (strain ATCC
29342) >gi|1673995|gb|AAB95970.1| (AE000029)
isoleucine-tRNA ligase [Mycoplasma pneumoniae]
Length = 861
Score = 214 bits (540), Expect = 3e-54
Identities = 201/820 (24%), Positives = 351/820 (42%), Gaps = 110/820 (13%)
Query: 12 EPKWQKYWLEEKIYK--YRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRM 69
E ++Q +W ++IY+ +R +++KP + PP+ +G +H+GH L+ D + R +
Sbjct: 24 EQQFQAFWQSKRIYQKLHRQNKDKPQKILHDGPPYANGNIHVGHALNKILKDFVLRSWNL 83
Query: 70 RGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKK--------CVEWTWQAIEAMR 121
+G+ +F G+D HGLP E ++K P+ + C ++ I +
Sbjct: 84 QGFGTVFIPGWDCHGLPIE------HAVSKKDPQHYASLSLSEKRDLCKQFALSQIAIQK 137
Query: 122 KQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKA 181
QF R+G D+ Y T+D+ ++ L+ KK LI++ P YW P RTSLA+A
Sbjct: 138 AQFQRLGLLNDFSKYYKTIDESFQQNELDLFLQAVKKDLIFQALKPTYWSPVSRTSLAEA 197
Query: 182 EVGYVEEEGYLYYIKLPLADGSGY-----IPIATTRPELMPACVAVFVHP---------D 227
E+ Y E + Y+ + + + + TT P +P A+ VHP +
Sbjct: 198 EIEYKEVKTIGLYLTFTVVQSAVLNSGTKLLVWTTTPWTLPTNQAIAVHPQFEYLLFTYN 257
Query: 228 DERY---------------------------KHLVGKKVKLPIYEREVPILADEDVDPNF 260
+E+Y L K +Y++ P+L V N
Sbjct: 258 NEQYVVLASLFESLKTKFGWTDAIQVQTISGSQLQNTTYKHCLYDKVNPVLLGNHVLCNE 317
Query: 261 GTGAVYNC-TYG-DEQDIVWQKRYNLPVIIAINEDGTMNE--NAGPYAGLKVEEARKKIA 316
GTG V+ YG D+ + Q + N +++++E G N+ N GL +A I
Sbjct: 318 GTGLVHTSPAYGLDDFYLCKQNKLN-EALVSLDEKGVFNDTLNDPVLTGLFYLKANDVII 376
Query: 317 EDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINW 376
E L++ E HR H RS P+ KQ FI+ K ++ + K + +
Sbjct: 377 ERLKQHHNFVFSESFLHRE-PHDWRSK--TPVIYRASKQLFIKTKSIQSKLKRQIKRVKF 433
Query: 377 YPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPARE--------EDLPV 428
RL++ +W ISRQRV+G P P N ++ + +
Sbjct: 434 VNNKNKERLQEMLLQRA-EWCISRQRVWGLPIPLIYADNQPLLDVTTIKYTIQQLKKYGI 492
Query: 429 DPRFDKP------PVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKK 482
D F+K P + P G E + TD L+ W DS T ++
Sbjct: 493 DSWFEKDINFFLNPKKIQP--GVEYKKETDTLEVWFDSGSTYNVLIS------------- 537
Query: 483 WFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYG 542
+ NFP L +G+D R W + T + P+K ++ +G G KMSKS G
Sbjct: 538 -NKLNFPADLYLEGSDQYRGWFNSSASCGIIQTDQLPFKSLISHGFTLDEHGNKMSKSLG 596
Query: 543 NVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWN-IYRFAERHIK 601
NVV P ++ +YGAD LRLW D+ + +++ N + RF ++
Sbjct: 597 NVVDPLKLCDQYGADILRLWVTNVDWQVDNRIGDNIIKQIVEQYRRIRNSLLRFILGNLN 656
Query: 602 DFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFI-WHEVADDYI 660
F++ + KD D+ ++ + + +++ + L++Y F + + F+ W ++ Y
Sbjct: 657 HFNFGEMKDYRFALEDKIVIHKTNALVQELHQWLKQYNFLNCLKAINKFVLW--LSGWYF 714
Query: 661 EMVKYRLYGDDEESKLK-AKVALYELLYNVML-LLAPFVPHITEEIYHAMFKDKIGEKSV 718
E++K LY D + + + AK A+ ++ ++ L F+PH E+ + K SV
Sbjct: 715 EIIKDTLYCDAKTNPNRVAKQAVLNYIFTQLIGFLNIFIPHTAEDAWQNYLLPK-KPVSV 773
Query: 719 HLLSWPEYRE-------DRIDEKAEKLGELARKVVSEMRK 751
+L + P + DR+ E + + A + + R+
Sbjct: 774 NLFAGPAMFKVANVKGLDRLHESFSAIKDRAYAAIEQARQ 813
>sp|O58698|SYL_PYRHO LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437640|pir||H71087 leucine--tRNA ligase (EC
6.1.1.4) - Pyrococcus horikoshii
>gi|3257379|dbj|BAA30062.1| (AP000004) 967aa long
hypothetical leucyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 967
Score = 208 bits (525), Expect = 2e-52
Identities = 261/1016 (25%), Positives = 425/1016 (41%), Gaps = 209/1016 (20%)
Query: 11 IEPKWQKYWLEEKIYKYRLDEN--KPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKR 68
IE KWQK WLE KI++ + + + + I P+ SG LH+GH ++T D+IAR+KR
Sbjct: 9 IEEKWQKRWLEAKIFEPNIRDKPKEKKFYITVAFPYLSGHLHVGHARTYTIPDVIARFKR 68
Query: 69 MRGYNVLFPQGFDNHGLPTELKVE-------KEFGITKDQ---PEEFLKKCVEWTWQA-- 116
M+GYNVLFP + G P E K I +D PEE L WT++
Sbjct: 69 MQGYNVLFPMAWHITGSPIVGIAERIKNRDPKTIWIYRDVYKVPEEIL-----WTFEDPI 123
Query: 117 ------IEAMRKQFIRIGYSADWDLEYHTMDDW--YKAAVQKSLLEFYKKGLIYREEHPV 168
++A ++ FIR G+S DW E++T + + ++ + +KG I + H V
Sbjct: 124 NIVKYFMKAAKETFIRAGFSVDWSREFYTTSLFPPFSKFIEWQFWKLKEKGYIVKGAHRV 183
Query: 169 YWCPKCRTSLAKAEVGYVEEEGYLYYI--KLPLADGSG--YIPIATTRPELMPACVAVFV 224
W P T L ++ E+ L YI K L + Y+P AT RPE + ++V
Sbjct: 184 RWDPVVGTPLGDHDLMEGEDVPILDYIIIKFELRENGEVIYLPAATLRPETVYGVTNMWV 243
Query: 225 HPD---------------------DERYK-----------------HLVGKKVKLPIYER 246
+P+ + YK L+GK V+ P+
Sbjct: 244 NPNATYVKAKVRRKDKEETWIVSKEAAYKLSFQDREIEVIEEFKGEKLIGKYVRNPVSGD 303
Query: 247 EVPILADEDVDPNFGTGAVYNCT----------------------YGDEQDIVWQKRY-- 282
EV IL E VDP+ TG V + Y + IV Y
Sbjct: 304 EVIILPAEFVDPDNATGVVMSVPAHAPFDHVALEDLKRETEILEKYDIDPRIVENITYIS 363
Query: 283 --------NLPVIIAINEDGTMNEN-----------------------AGPYAGLKVEEA 311
+ P + +N+ G ++ PY G V+E
Sbjct: 364 LIKLEGYGDFPAVEEVNKLGIKSQKDKEKLEQATKTIYKAEYHKGIFKVPPYEGKPVQEV 423
Query: 312 RKKIAEDLEKMGL---LYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRV--KDFTDE 366
++ IA+++ + G+ +Y+ + K+ + R R A I+++ QWFI ++ ++
Sbjct: 424 KEAIAKEMLEKGIAEIMYEFAE-KNVISRFGNR----AVIKII-HDQWFIDYGNPEWKEK 477
Query: 367 IVKVAKEINWYPED---MFLRLKDWAESMDWDWVISRQRVFGTPFPF---WVCKN----- 415
K + + PE F + DW + +R+ GTP P+ WV ++
Sbjct: 478 ARKALERMKILPETRRAQFEAIIDWLDKK----ACARKIGLGTPLPWDPEWVIESLSDST 533
Query: 416 ---------GHIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLI 466
HI R+E +DP P E L+ + I I
Sbjct: 534 IYMAYYTISRHINKLRQEG-KLDPEKLTPEFFDYIFLEEFSEDKEKELE--KKTGIPAEI 590
Query: 467 ITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPW-KDIVI 525
I E K+ FE+ +P R G D+I + IF + ++ W K I +
Sbjct: 591 I----------HEMKEEFEYWYPLDWRCSGKDLIPNHLTFFIFNHVAIFREEHWPKGIAV 640
Query: 526 NGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWETVDYNFRF 585
NG +G+KMSKS GNV+ + I + GAD +RL+ ++ D F W +
Sbjct: 641 NGF-GTLEGQKMSKSKGNVLNFIDAIEENGADVVRLYI-MSLAEHDSDFDWRRKEVGK-- 696
Query: 586 LQKVWNIYRFAERHIKDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITR 645
L+K I RF E + +YE ++EL+ +DRW+L RL++ IK T LE +R TR
Sbjct: 697 LRK--QIERFYELISQFAEYEVKGNVELKDIDRWMLHRLNKAIKETTNALEEFR----TR 750
Query: 646 ELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIY 705
+ + ++ + +D + R G D+E+K + L L + L+APF PHI EE++
Sbjct: 751 TAVQWAFYSIMND-LRWYLRRTEGRDDEAK---RYVLRTLADVWVRLMAPFTPHICEELW 806
Query: 706 HAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLE 765
+ GE V L WPE E+ +E E E R V+ ++++ AK+E
Sbjct: 807 EKLG----GEGFVSLAKWPEPVEEWWNETIEAEEEFIRSVMEDIKEIIEV------AKIE 856
Query: 766 HVAIYALESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLV 825
+ + + +D K ++ + + FK + + E++ + K + KL+
Sbjct: 857 NAKRAYIYTAEDWKWKVAEV-----VSEKRDFKSSMEELMKDSEIRKHGKEVAKIVQKLI 911
Query: 826 -PRIVEHLKNNAESIAREIKENGKVEFEID------GEKVELTKEDVMIKKEVFSE 874
R + + N E RE KE + E I+ +K K+ + +K +F E
Sbjct: 912 KERTFDVKRINEEKALREAKEFMEKELGIEIIINPTEDKGGKKKQAMPLKPAIFIE 967
>sp|P46215|SYI_SULAC ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|598398|gb|AAC41447.1| (L37106) transfer RNA-Ile
synthetase [Sulfolobus acidocaldarius]
Length = 552
Score = 206 bits (520), Expect = 7e-52
Identities = 163/560 (29%), Positives = 259/560 (46%), Gaps = 90/560 (16%)
Query: 81 DNHGLPTELKVEKEFGIT-------KDQPEEFLKKCVEWTWQAIEAMRKQFIRIGYSADW 133
D HGLP E++ EK GI K + F+ KC E+ +++ + F +G DW
Sbjct: 1 DTHGLPIEVETEKRLGIKSKAEIIEKVGVDNFISKCKEFAVNNSKSLTQNFRNLGIFMDW 60
Query: 134 DLEYHTMDDWYKA---AVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVG-YVEEE 189
+ Y T ++ Y + AV KS+ ++GL+Y+ H ++WC +C T+LA EV Y + E
Sbjct: 61 ENPYFTFNNDYISNSWAVIKSI----RRGLLYKGVHVLHWCSRCETTLADYEVSEYRDLE 116
Query: 190 GYLYYIKLPL-ADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVGKKVK-------- 240
Y+K + + + Y+ I TT P +PA V V ++ D E VG ++
Sbjct: 117 DPSIYVKFRVKGEPNRYLVIWTTTPWTLPANVFVMINKDFEYADVRVGDEILVIAKDRVK 176
Query: 241 -------------LPIYEREVPI-------LAD------------------EDVDPNFGT 262
L +Y+ E + LAD E V GT
Sbjct: 177 ELMKEARIKEYKILRVYKGEELLGLEYEHPLADIVSAQSKINNHHKVLDGGEAVTLQEGT 236
Query: 263 GAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKM 322
G V++ + D K+Y++PV++ +N+ G +++G YAG V A ++I DL++
Sbjct: 237 GLVHSAPGHGDVDFEIGKKYDMPVVMLVNDKGEFTQDSGKYAGKYVRSASEEIISDLKQR 296
Query: 323 GLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDMF 382
L KI H R+ C P+ L +QWFI V D ++ + W P+
Sbjct: 297 SALLHASKIVH---RYPVCWRCKTPLILRAIEQWFIAVSKLKDHLMGEIDRVRWIPDWGK 353
Query: 383 LRLKDWAESMDWDWVISRQRVFGTPFPFWVCKN-GHIIPAREED----LPVD-------- 429
R+ + + + DWVISRQR +GTP P WVC N +II D +P++
Sbjct: 354 TRIGNMVKEVR-DWVISRQRFWGTPLPIWVCSNCQNIIVVGGVDELGKIPINQVPQDLHR 412
Query: 430 PRFDKPPVEKCPVCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFP 489
P D ++ V G + ++DV D W DS + A G + K+W E P
Sbjct: 413 PWIDSVVLDVKNVEG-QARRISDVADVWFDSGVA-------FFASLGQDWRKRWSELG-P 463
Query: 490 TALRPQGTDIIRTWAFYTIFRT-FKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPD 548
L +G D +R W F+++ RT L K P++ ++++G + GR+M KS GN V P
Sbjct: 464 VDLVLEGHDQLRGW-FFSLLRTGVILMDKAPYEAVLVHGFMLDEQGREMHKSSGNYVEPS 522
Query: 549 EVIPKYGADALRLWTALAPP 568
+V+ KYG +++ L P
Sbjct: 523 QVVSKYGQRYVKIMVTLEIP 542
>sp|Q9X7E5|SYI_MYCLE ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|4539131|emb|CAB39575.1| (AL049478) putative
isoleucyl-tRNA synthetase [Mycobacterium leprae]
Length = 1059
Score = 206 bits (518), Expect = 1e-51
Identities = 227/930 (24%), Positives = 383/930 (40%), Gaps = 138/930 (14%)
Query: 11 IEPKWQKYWLEEKIYKYRLD--ENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKR 68
+E + YW + ++ + ++ P Y PPF +G H GH+L+ DI+ RY+
Sbjct: 25 LEAQVLDYWSNDDTFRASIARCDDAPEYVFYDGPPFANGLPHYGHLLTGYVKDIVPRYRT 84
Query: 69 MRGYNVLFPQGFDNHGLPTELKVEKEFGIT-KDQPEE-----FLKKCVEWTWQAIEAMRK 122
M GY V G+D HGLP EL+VE++ GIT K Q + F + C + + E +
Sbjct: 85 MCGYKVERRFGWDTHGLPAELEVERQLGITDKSQIDAMGIAAFNEACRKSVLRYTEEWQA 144
Query: 123 QFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAE 182
R D+D +Y T+D Y +V + + + KGL Y + +C + T L+ E
Sbjct: 145 YVTRQARWVDFDNDYKTLDLSYMESVIWAFKQLWDKGLAYESYRVLPYCWRDETPLSNHE 204
Query: 183 VG-----YVEEEGYLYYIKLPLADGS------GYIPIATTRPELMPACVAVFVHPD---- 227
+ Y + + + G Y+ + TT P +P+ +AV VHPD
Sbjct: 205 LRMDDDVYQSRQDPAVTLGFKVLGGDDEDLVGAYLLVWTTTPWTLPSNLAVAVHPDVTYV 264
Query: 228 DERY--KHLVGKKVKLPIYEREV-----------------------------------PI 250
D R + V + +L Y RE+ +
Sbjct: 265 DVRAGDRRFVLAQARLTAYARELGDEPEVLATYRGADLLGRHYLPPFQYFYESARNAFQV 324
Query: 251 LADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEE 310
L + V + GTG V+ E D+ + + + ++ +G + Y G V E
Sbjct: 325 LPGDFVTTDDGTGIVHIAPAYGEDDMATADKVGIVPVTPVDSNGCFDATVPDYQGQHVFE 384
Query: 311 ARKKIAEDLEKMG--------LLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKD 362
A +I DL+ +L + E +H H R C P+ WF+ V +
Sbjct: 385 ANAQIIRDLKNQSGSAAVNGAVLLRHETYEHPY-PHCWR--CRNPLIYRAVSSWFVAVTE 441
Query: 363 FTDEIVKVAKEINWYPEDMFLRLKD-----WAESMDWDWVISRQRVFGTPFPFWVCKNGH 417
F D +V++ ++I WYPE +KD W + DW ISR R +GTP P W +
Sbjct: 442 FRDRMVELNQQITWYPE----HVKDGQFGKWLQGAR-DWSISRNRYWGTPIPVWKSDDPD 496
Query: 418 I--------IPAREEDLPVDP-RFDKPPVEKC-------PVCGAEIEPVTDVLDCWVDSS 461
+ E D V P +P +++ P + + + DV D W DS
Sbjct: 497 YPRIDVYGSLDELERDFGVRPTNLHRPYIDELTRPNPDDPTGLSTMRRIPDVFDVWFDSG 556
Query: 462 ITPLIITRWHEAIKGDE--------EAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFK 513
P + H + D+ ++ K + ++P + R W FYT+
Sbjct: 557 SMPY--AQVHYPFENDDWFDGFDSADSDKQVDAHYPGDFIVEYIGQARGW-FYTLHVLAT 613
Query: 514 LTGKKP-WKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPP---G 569
+P +K + +G+V G +G+KMSKS N E+ + G+DA+R W +A P G
Sbjct: 614 ALFDRPAFKTCIAHGVVLGSNGQKMSKSLRNYPDVTEIFDRDGSDAMR-WFLMASPILRG 672
Query: 570 EDHPFKWETVDYNFR-FLQKVWNIYRFAERHIKDFDYEKYKDIELEPLDRWILSRLHRII 628
+ + R L +WN Y F + + D+ LDR+IL++L +
Sbjct: 673 GNLIITEPGIREGMRQVLLPLWNAYSFLALYAPKIG-TWHTDVS-HVLDRYILAKLAVLR 730
Query: 629 KFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYN 688
++ +E + +L F + + Y+ + R + +D + A L+ +L
Sbjct: 731 DDLSQAMEVCDISGACEQLRQFT-EPLTNWYLRRSRARFWDED----VDAIDTLHTVLEV 785
Query: 689 VMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSE 748
L AP +P ITE I+ ++ G +SVHL WP+ + D + + R+V S
Sbjct: 786 TARLAAPLLPLITEIIWRSV----TGGRSVHLTDWPQANQLPADPDLVAVMDQVRQVCSA 841
Query: 749 MRKYKNSHGMPLNAKLEH--VAIY---ALESYDDLKLIEKDIAGTMNIEKLEIFKGEPQL 803
+ + + + L VA+Y L+ Y DL I +N++++E+
Sbjct: 842 ASSLRKAKKLRVRLPLPKLVVAVYNSQRLKPYIDL------IGDELNVKQIELTDAIDTY 895
Query: 804 EERIVEVKPNYKRIGPRYGKLVPRIVEHLK 833
E N + GPR G+ V ++ +K
Sbjct: 896 GR--FEFTVNARVAGPRLGRDVQAAIKVVK 923
>sp|P73274|SYL_SYNY3 LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437530|pir||S77455 leucine--tRNA ligase (EC
6.1.1.4) - Synechocystis sp. (strain PCC 6803)
>gi|1652380|dbj|BAA17302.1| (D90905) leucyl-tRNA
synthetase [Synechocystis sp.]
Length = 869
Score = 201 bits (506), Expect = 3e-50
Identities = 234/927 (25%), Positives = 365/927 (39%), Gaps = 257/927 (27%)
Query: 6 YDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIAR 65
Y+ EIE KWQ+ W E + K + + P + + P+ SG LH+GHV ++T D+IAR
Sbjct: 5 YNAGEIEQKWQQRWAEWGLDKTPIASDLPKFYALSMFPYPSGNLHMGHVRNYTITDVIAR 64
Query: 66 YKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMRKQFI 125
KRM+GY VL P G+D GLP E E GI Q WT + I MR Q
Sbjct: 65 LKRMQGYQVLHPMGWDAFGLPAE-NAAIERGIPPKQ----------WTEKNIAQMRAQLQ 113
Query: 126 RIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV-- 183
++G S DW+ E T Y Q LEF++ GL Y++E V W P +T LA +V
Sbjct: 114 QLGLSIDWEREVATCAPDYYRWTQWLFLEFFQAGLAYQKEATVNWDPIDQTVLANEQVDS 173
Query: 184 -------GYVEEEGYL--YYIKL------------------------------------- 197
G + E L +++K+
Sbjct: 174 EGRSWRSGAMVERKLLRQWFLKITDYAEALLNDLEQLTGWPERVKLMQSHWIGKSVGAYL 233
Query: 198 --PLADGSGYIPIATTRPELMPACVAVFVHPDD---------------ERYKHLVGKKVK 240
P+ D I + TTRP+ + V + P+ + + +V K+ +
Sbjct: 234 EFPIKDSQEKIAVFTTRPDTVYGVTYVVLAPEHPLTKVVTTAEQQGTVDEFVAMVAKESE 293
Query: 241 L--------------------PIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQK 280
+ P E+PIL + V +GTGAV D++D + +
Sbjct: 294 IERTAEDKPKRGVKTGGIAINPFNGEEIPILIADYVLYEYGTGAVMGVPAHDQRDFKFAQ 353
Query: 281 RYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTE 340
NLP+ + I D N + + + Y + + + T
Sbjct: 354 DNNLPMQVVIIPDDADNSDV--------------------NLTVAYTEAGVMVNSAQFTG 393
Query: 341 RSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISR 400
+S PK + I+K A++ ++ + RL+ DW+ISR
Sbjct: 394 MAS--------PKAK---------QAIIKFAEDNDYGRAKVQYRLR--------DWLISR 428
Query: 401 QRVFGTPFPFWVCKNGHIIPAREEDLPVD--------PRFDKPPVE-------KCPVCGA 445
QR +G P P C + +P +DLPV+ R P + CP CG
Sbjct: 429 QRYWGCPIPIIHCDDCGAVPVPTKDLPVELPDNVEFSGRGPSPLAKLEDWINVPCPSCGK 488
Query: 446 EIEPVTDVLDCWVDSSITPLIITRWHEA------IKGDEEAKKWFEHNFPTALRPQGTDI 499
TD +D ++DSS R+ +A G++ A H P G +
Sbjct: 489 PARRETDTMDTFIDSS---WYFLRYADAQNTELPFDGEKVA-----HWLPVDQYVGGIEH 540
Query: 500 IRTWAFYTIFRTFKLTG------KKPWKDIVINGMVAG---------------------- 531
Y+ F T L K+P++ ++ GMV G
Sbjct: 541 AILHLLYSRFFTKVLADRQLIPVKEPFQKLLTQGMVQGITYKNPTTGKYVPAKDLQTGQQ 600
Query: 532 ---------PDG--------RKMSKSYGNVVAPDEVIPKYGADALRLWTAL-APPGEDHP 573
PD KMSKS N V P EV+ KYGAD R++ APP +D
Sbjct: 601 VIDPKDPKDPDSGEPLQVFYEKMSKSKFNGVDPQEVLAKYGADTARMFILFKAPPEKDLE 660
Query: 574 FKWETVDYNFRFLQKVWNIYRFAERHIKD-----FDYEKYKDIELEPL---DRWILSRLH 625
+ V+ FRFL +VW R +I D F + EPL ++ + +H
Sbjct: 661 WDDADVEGQFRFLNRVW---RLVTDYIGDPAGIRFAVRPETLVTNEPLTKAEKDLRRAIH 717
Query: 626 RIIKFATEEL-ERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYE 684
IK E+L + Y+FN E+M +A +++ + +Y + E+
Sbjct: 718 GAIKEVAEDLNDDYQFNTAISEMMKLSNALIA--ATDLISFPVYQEGIET---------- 765
Query: 685 LLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARK 744
++LLLAPF PH+TEE++H + + S+H +W + +D A L E+
Sbjct: 766 ----LLLLLAPFAPHLTEELWHRLGR----TDSIHQQAWLQ-----VDPTALVLDEIT-L 811
Query: 745 VVSEMRKYKNSHGMPLNA---KLEHVA 768
V+ + K + + +P +A +LE +A
Sbjct: 812 VIQVLGKTRGTITVPASADKTQLEELA 838
>gb|AAF49539.1| (AE003528) CG5414 gene product [Drosophila melanogaster]
Length = 890
Score = 199 bits (501), Expect = 1e-49
Identities = 193/799 (24%), Positives = 315/799 (39%), Gaps = 131/799 (16%)
Query: 2 LPKKYDPNEI-------EPKWQKYWLEEKIYKYRLDEN-KPSYAIDTPPPFTSGTLHLGH 53
LPK PN + + + K + + RL E KP++ + PP+ +G LH+GH
Sbjct: 17 LPKTKFPNRLTAAKREEQERLNKIAVSYAYQEQRLAEKGKPTFVLHDGPPYANGQLHMGH 76
Query: 54 VLSHTWIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWT 113
++ DI R + G V + G+D HGLP ELK +E +K +
Sbjct: 77 AVNKILKDITLRQRVAHGQRVNYIPGWDCHGLPIELKATST--APGQSAQEIRQKSRAFA 134
Query: 114 WQAIEAMRKQFIRIGYSADWDLE--YHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWC 171
W+AI++ +++F G A+W + Y T + + Y+KGL+YR+ PVYW
Sbjct: 135 WEAIKSQKEEFSSWGILANWQKDNIYMTFQPEFIVNQLEMFYNLYEKGLVYRDLKPVYWS 194
Query: 172 PKCRTSLAKAEVGY----VEEEGYLYYIKLP----LADGSGYIPIATTRPELMPACVAVF 223
P RT+LA+AE+ Y + Y+ + P + D Y + TT P +P+ A+
Sbjct: 195 PSSRTALAEAELEYDANHISPSVYVRFALNPSSFDVKDKQIYALVWTTTPWTLPSNQAIC 254
Query: 224 VHPD-------------DERY---------------------KHLVGKKVKLPIYEREV- 248
+ DE Y +HL G+ + Y +
Sbjct: 255 YNASLEYVIVRLSDRNQDELYLMASALMADFEANTQLKCEIVQHLSGELLSKLSYNHPID 314
Query: 249 ------PILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAGP 302
P V + GTG V+ +D + +PV +NE+GT + A
Sbjct: 315 KEQSNLPFFDASHVQDSKGTGLVHTAPAHGPEDFLVSLTQKIPVKCFVNEEGTYTKEAPD 374
Query: 303 Y-AGLKVEE-----ARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQW 356
+ G V + +IAED+ L I R + P+ + +QW
Sbjct: 375 FLRGKSVLDQGNSLVLDRIAEDVVHSSKLEHSYPIDWRTKK---------PVIIRASEQW 425
Query: 357 FIRVKDFTDEIVKVAKEINWYP----EDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWV 412
FI + +++ YP E L + + W ISRQR +G P P
Sbjct: 426 FINTEKLKTPAADALEQVEIYPRANAEASKKALLTQLQKRPY-WCISRQRAWGVPIPVLY 484
Query: 413 CKNG-----------HIIPAREEDLPVDPRFDKPPVEKCPVC--------GAEIEPVTDV 453
+ H+ ++ +D + K E P ++ TD+
Sbjct: 485 SRESGKVVLNSALIEHLCNLLRKEGSIDFWWVKSVEELVPEHLLRELHHEAKDLVKGTDI 544
Query: 454 LDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFK 513
LD W DS T W + D+ A + E G D W ++ +
Sbjct: 545 LDIWFDSGST------WSAVLGKDKIADLYLE----------GYDQFTGWFQSSLLMSIA 588
Query: 514 LTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHP 573
P+K + ++G G KMSKS GNV++P ++ KYG DALR W A H
Sbjct: 589 ARECAPYKALFVHGFTVDEKGYKMSKSLGNVISPKQITKKYGTDALRWWVA------SHG 642
Query: 574 FKWETVDYNFRFLQKVWN---IYRFAERHIKDFDYEKYKDIEL------EPLDRWILSRL 624
+ ++ + + LQ+ R R++K EK +L L+R++LS+L
Sbjct: 643 TQHMSITVSDKLLQQAAENLCKIRGTMRYLKGVIGEKQSGEKLIRTSDKSYLNRYLLSQL 702
Query: 625 HRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYE 684
+ + Y +N + + FI ++V+ Y+ ++K RLY D+ L + L
Sbjct: 703 VEFESEVEKLYQAYEYNRVVACVQNFIANQVSAVYVHLIKDRLYCGDDHELLAIRQTLTH 762
Query: 685 LLYNVMLLLAPFVPHITEE 703
+ L P VP + EE
Sbjct: 763 CYQQLCKSLWPIVPFLVEE 781
>gb|AAK40902.1| Leucyl-tRNA synthetase (leuS-2) [Sulfolobus solfataricus]
Length = 944
Score = 197 bits (496), Expect = 4e-49
Identities = 236/995 (23%), Positives = 399/995 (39%), Gaps = 181/995 (18%)
Query: 9 NEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKR 68
N I KWQ W E+KIY+ + +KP + P+ + H+GH ++ DI+ARYKR
Sbjct: 2 NNIAYKWQTRWEEDKIYESNPNPSKPKFFTTVAFPYPNSPWHIGHGRTYVTGDILARYKR 61
Query: 69 MRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPE--EFLKKCVEWTWQAI--------- 117
MRGYNVLFP F G P + I K E E K E + I
Sbjct: 62 MRGYNVLFPMAFHYTGTPIMAMAD---AIAKGDKELIETFKDIYEISPDVIPRMSDPLFM 118
Query: 118 -----EAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCP 172
E ++ IG DW E+ T+D + + V + KG I ++ HPV WCP
Sbjct: 119 ANYFKEDIKASMREIGLGIDWRREFTTIDPEFSSFVTWQFHKLQSKGYIVKDTHPVGWCP 178
Query: 173 KCRTSLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPD----- 227
+ + E ++ + G P AT RPE + A++++P
Sbjct: 179 VHHIPVGMHDTKGDVEPEIGEFVLIYFNSEKGIFPAATLRPETIFGATALWINPSEMYVV 238
Query: 228 ---------------------------DERYK--HLVGKKVKLPIYEREVPILADEDVDP 258
+E+ K LVG KV+ PI + + +L + VD
Sbjct: 239 ASMLGKKMILSEKAAAKLSFQIDDIEIEEKIKGSKLVGLKVENPITGKHIAVLGADFVDV 298
Query: 259 NFGTGAVYNCTYGDEQDIVWQKR----YNLPVIIAINEDGTMNENAGPYAGLKVEEARKK 314
+ GTG V + D + K+ N+ +I I +G N A VE+ K
Sbjct: 299 SLGTGVVMSVPAHAPFDYYYSKKTFKNNNIEIIPVITVEGLGNALAKDV----VEKNNPK 354
Query: 315 IAEDLEKM-GLLYKKEKIK-------HRVLRHTERSS----------------------- 343
EDL+K+ +Y+ E K ++R R+
Sbjct: 355 SDEDLKKLTEYVYRTEYNKGVLRSDLGNLIREEYRNELKSLGGLPVPKGRELITNFLISK 414
Query: 344 ---------------CMAPIEL---LPKKQWFIRV--KDFTDEIVKVAKEINWYPEDMFL 383
C E+ + K QWF+ K++ + K +IN PE+
Sbjct: 415 GLGRKIFEVMNKPVYCRCGTEIVVKILKDQWFLDYSNKEWKELARKSLSKINVIPEE--- 471
Query: 384 RLKDWAESMDW--DWVISRQRVFGTPFPF---WVCKN---------GHIIPAREEDLPVD 429
KD+ +++W +R R GTP P+ W+ ++ + I + + +
Sbjct: 472 SRKDFEFTIEWLEKRACARTRGLGTPLPWDKKWIIESLSDSTIYMAYYTISHKIKQYKLS 531
Query: 430 PRFDKPPVEKCPVCG-AEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNF 488
P + G +E +++ + I II + E F + +
Sbjct: 532 PSKLTQEFWDYVMLGIGNLEEISE------KTGIPSNIIKEFREE----------FLYWY 575
Query: 489 PTALRPQGTDIIRTWAFYTIFRTFKLTGKKPW-KDIVINGMVAGPDGRKMSKSYGNVVAP 547
P +R G D+I + IF + + W K I +NG+V +G+KMSKS N++
Sbjct: 576 PLDIRHSGKDLIPNHLTFFIFNHAAIFQENLWPKAIAVNGLVL-YEGKKMSKSLRNIIPL 634
Query: 548 DEVIPKYGADALRL-WTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDFDYE 606
+ + YG D +R+ ++ A G D F V L+K++ +++ + + D
Sbjct: 635 RKGLKMYGVDVMRIAVSSTADMGSDVNFSESLVKTVGETLRKMYELFKSLDNYTGDI--- 691
Query: 607 KYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYR 666
L ++W+LSR++ I T +E EL+ F++ D+Y MV
Sbjct: 692 ------LGFPEKWLLSRIYEITSSTTRHMEALELRDAVNELL-FVFSSDLDEYFGMVSAE 744
Query: 667 LYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEY 726
G + +K+ L E+L + L+ PF PH+ EEI+H + K K + WPE
Sbjct: 745 --GREANNKV-----LREVLTIWLKLITPFAPHLAEEIWHEILKQK---TYIVNEGWPEV 794
Query: 727 REDRIDEKAEKLGELARKVVSEMRKYKN-SHGMPLNAKLEHVAIYALESYDDLKLIEKDI 785
++DE E +++V ++R N G P + + IYAL ++L+ I
Sbjct: 795 EGSKMDELTLLEHEYMKRIVEDIRSILNIFKGTP-----KLIKIYALNDSRYMELLRDAI 849
Query: 786 AGTMNIEK-LEIFKGEPQLEERIVEVKPNYK-RIGPRYGKLVPRI----VEHLKNNAESI 839
++K ++I K + + + RI++ N I + KLV V+ L ++ I
Sbjct: 850 VANGQMKKFMDIHKPKSREDARILQKIFNESLEIDDKMKKLVTNYNINEVDVLNKLSKYI 909
Query: 840 AREIKENGKVEFEIDGEKVELTKEDVMIKKEVFSE 874
R++ + +E + K KE + ++ + E
Sbjct: 910 RRKLNVDILIEPYDEEVKKTYNKEAMPLRPAIIIE 944
>emb|CAB57710.1| (Y18930) isoleucyl-trna synthetase [Sulfolobus solfataricus]
Length = 944
Score = 197 bits (496), Expect = 4e-49
Identities = 236/995 (23%), Positives = 399/995 (39%), Gaps = 181/995 (18%)
Query: 9 NEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKR 68
N I KWQ W E+KIY+ + +KP + P+ + H+GH ++ DI+ARYKR
Sbjct: 2 NNIAYKWQTRWEEDKIYESNPNPSKPKFFTTVAFPYPNSPWHIGHGRTYVTGDILARYKR 61
Query: 69 MRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPE--EFLKKCVEWTWQAI--------- 117
MRGYNVLFP F G P + I K E E K E + I
Sbjct: 62 MRGYNVLFPMAFHYTGTPIMAMAD---AIAKGDKELIETFKDIYEISPDVIPRMSDPLFM 118
Query: 118 -----EAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCP 172
E ++ IG DW E+ T+D + + V + KG I ++ HPV WCP
Sbjct: 119 ANYFKEDIKASMREIGLGIDWRREFTTIDPEFSSFVTWQFHKLQSKGYIVKDTHPVGWCP 178
Query: 173 KCRTSLAKAEVGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPD----- 227
+ + E ++ + G P AT RPE + A++++P
Sbjct: 179 VHHIPVGMHDTKGDVEPEIGEFVLIYFNSEKGIFPAATLRPETIFGATALWINPSEMYVV 238
Query: 228 ---------------------------DERYK--HLVGKKVKLPIYEREVPILADEDVDP 258
+E+ K LVG KV+ PI + + +L + VD
Sbjct: 239 ASMLGKKMILSEKAAAKLSFQIDDIEIEEKIKGSKLVGLKVENPITGKHIAVLGADFVDV 298
Query: 259 NFGTGAVYNCTYGDEQDIVWQKR----YNLPVIIAINEDGTMNENAGPYAGLKVEEARKK 314
+ GTG V + D + K+ N+ +I I +G N A VE+ K
Sbjct: 299 SLGTGVVMSVPAHAPFDYYYSKKTFKNNNIEIIPVITVEGLGNALAKDV----VEKNNPK 354
Query: 315 IAEDLEKM-GLLYKKEKIK-------HRVLRHTERSS----------------------- 343
EDL+K+ +Y+ E K ++R R+
Sbjct: 355 SDEDLKKLTEYVYRTEYNKGVLRSDLGNLIREEYRNELKSLGGLPVPKGRELITNFLISK 414
Query: 344 ---------------CMAPIEL---LPKKQWFIRV--KDFTDEIVKVAKEINWYPEDMFL 383
C E+ + K QWF+ K++ + K +IN PE+
Sbjct: 415 GLGRKIFEVMNKPVYCRCGTEIVVKILKDQWFLDYSNKEWKELARKSLSKINVIPEE--- 471
Query: 384 RLKDWAESMDW--DWVISRQRVFGTPFPF---WVCKN---------GHIIPAREEDLPVD 429
KD+ +++W +R R GTP P+ W+ ++ + I + + +
Sbjct: 472 SRKDFEFTIEWLEKRACARTRGLGTPLPWDKKWIIESLSDSTIYMAYYTISHKIKQYKLS 531
Query: 430 PRFDKPPVEKCPVCG-AEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNF 488
P + G +E +++ + I II + E F + +
Sbjct: 532 PSKLTQEFWDYVMLGIGNLEEISE------KTGIPSNIIKEFREE----------FLYWY 575
Query: 489 PTALRPQGTDIIRTWAFYTIFRTFKLTGKKPW-KDIVINGMVAGPDGRKMSKSYGNVVAP 547
P +R G D+I + IF + + W K I +NG+V +G+KMSKS N++
Sbjct: 576 PLDIRHSGKDLIPNHLTFFIFNHAAIFQENLWPKAIAVNGLVL-YEGKKMSKSLRNIIPL 634
Query: 548 DEVIPKYGADALRL-WTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDFDYE 606
+ + YG D +R+ ++ A G D F V L+K++ +++ + + D
Sbjct: 635 RKGLKMYGVDVMRIAVSSTADMGSDVNFSESLVKTVGETLRKMYELFKSLDNYTGDI--- 691
Query: 607 KYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYR 666
L ++W+LSR++ I T +E EL+ F++ D+Y MV
Sbjct: 692 ------LGFPEKWLLSRIYEITSSTTRHMEALELRDAVNELL-FVFSSDLDEYFGMVSAE 744
Query: 667 LYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEY 726
G + +K+ L E+L + L+ PF PH+ EEI+H + K K + WPE
Sbjct: 745 --GREANNKV-----LREVLTIWLKLITPFAPHLAEEIWHEILKQK---TYIVNEGWPEV 794
Query: 727 REDRIDEKAEKLGELARKVVSEMRKYKN-SHGMPLNAKLEHVAIYALESYDDLKLIEKDI 785
++DE E +++V ++R N G P + + IYAL ++L+ I
Sbjct: 795 EGSKMDELTLLEHEYMKRIVEDIRSILNIFKGTP-----KLIKIYALNDSRYMELLRDAI 849
Query: 786 AGTMNIEK-LEIFKGEPQLEERIVEVKPNYK-RIGPRYGKLVPRI----VEHLKNNAESI 839
++K ++I K + + + RI++ N I + KLV V+ L ++ I
Sbjct: 850 VANGQMKKFMDIHKPKSREDARILQKIFNESLEIDDKMKKLVTNYNINEVDVLNKLSKYI 909
Query: 840 AREIKENGKVEFEIDGEKVELTKEDVMIKKEVFSE 874
R++ + +E + K KE + ++ + E
Sbjct: 910 RRKLNVDILIEPYDEEVKKTYNKEAMPLRPAIIIE 944
>pir||T04047 isoleucine--tRNA ligase homolog F24G24.120 - Arabidopsis thaliana
>gi|4538961|emb|CAB39785.1| (AL049488) isoleucine-tRNA
ligase-like protein [Arabidopsis thaliana]
>gi|7267729|emb|CAB78155.1| (AL161517) isoleucine-tRNA
ligase-like protein [Arabidopsis thaliana]
Length = 1254
Score = 197 bits (495), Expect = 6e-49
Identities = 179/664 (26%), Positives = 300/664 (44%), Gaps = 68/664 (10%)
Query: 234 LVGKKVKLPIYE-------REVPILADEDVDPNFGTGAVYNCTYGDEQDI-------VWQ 279
LVGKK + P+++ ++AD+ V + GTG V+ E D + +
Sbjct: 315 LVGKKYE-PLFDYFSDFSSEAFRVVADDYVTDDSGTGIVHCAPAFGEDDYRVCLLNKIIK 373
Query: 280 KRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHT 339
K NL ++A+++DG E ++G V++A K I E ++ G L K H
Sbjct: 374 KGENL--VVAVDDDGLFTERITHFSGRYVKDADKDIIEAVKAKGRLVKTGSFTHSY-PFC 430
Query: 340 ERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDMF-LRLKDWAESMDWDWVI 398
RS +P WF+RV+ ++++K ++ W P + R +W E+ DW I
Sbjct: 431 WRSDTPLIYRAVPS--WFVRVEQLKEKLLKSNEQTEWVPGYVKDKRFHNWLENAR-DWAI 487
Query: 399 SRQRVFGTPFPFWVCKNGHIIPARE-----EDLPVDPRFD--KPPVEKCPVCGAE----- 446
SR R +GTP P W+ +G + + E L FD + ++ + +
Sbjct: 488 SRSRFWGTPLPIWISDDGEEVVIMDSVEKLEKLSGVKVFDLHRHHIDHITIPSSRGDEFG 547
Query: 447 -IEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAF 505
+ V DV DCW +S P + I E K+ FE NFP +G D R W +
Sbjct: 548 VLRRVEDVFDCWFESGSMP------YAYIHYPFENKELFEKNFPGDFVAEGLDQTRGWFY 601
Query: 506 YTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTAL 565
+ + L K +K+++ NG+V DG+KM+K N P EVI +YGADA+RL+
Sbjct: 602 TLMVLSTALFEKPAFKNLICNGLVLAEDGKKMAKKLRNYPPPLEVIDEYGADAVRLYLIN 661
Query: 566 APPGEDHP--FKWETVDYNFRFLQKVW-NIYRFAERHIKDFDYE---KYKDIELEP---- 615
+P P FK E V + + W N YRF ++ K + E + +L
Sbjct: 662 SPVVRAEPLRFKKEGVLGVVKDVFLPWYNAYRFLVQNAKRLETEGGVPFVPTDLATIQSA 721
Query: 616 --LDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYG-DDE 672
LD+WI S +++F EE++ YR + L+ F+ + + Y+ + RL G E
Sbjct: 722 NILDQWIHSATQSLVRFVREEMDAYRLYTVVPRLLKFL-DNLTNIYVRFNRKRLKGRTGE 780
Query: 673 ESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKD-KIGEKSVHLLSWPEYREDRI 731
+ A L+ +L ++APF P TE +Y + K K E+SVH S P RE
Sbjct: 781 DDCHTALSTLFNVLLTSCKVMAPFTPFFTETLYQNLRKACKGSEESVHYCSIPP-REGME 839
Query: 732 DEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESYDDLKLIEKDIAGTMN- 790
E+ E K++ R + + +PL L+ + + + D + DI G +
Sbjct: 840 GERIELSVTRMMKIIDLARNIRERNKLPLKTPLKEMIVV----HPDADFL-NDITGVLRE 894
Query: 791 --IEKLEIFKGEP---QLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKNNAESIAREIKE 845
+E+L + P L+ ++ +P++ +G R GK + + + +K ++ +E
Sbjct: 895 YVLEELNVRSLVPCNDTLKYASLKAEPDFSVLGKRLGKSMGLVAKEVKEMSQKDILAFEE 954
Query: 846 NGKV 849
G+V
Sbjct: 955 AGEV 958
Score = 89.3 bits (218), Expect = 2e-16
Identities = 61/221 (27%), Positives = 107/221 (47%), Gaps = 14/221 (6%)
Query: 18 YWLEEKIYKYRLD--ENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRMRGYNVL 75
+W E +K +L EN P Y PPF +G H GH+L+ T DI+ RY+ M G++V
Sbjct: 22 FWTEIDAFKTQLKRTENLPEYIFYDGPPFATGLPHYGHILAGTIKDIVTRYQTMTGHHVT 81
Query: 76 FPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCVEWTWQAIEAMRKQFIRIGY 129
G+D HGLP E +++++ I + +++ ++C + + K R G
Sbjct: 82 RRFGWDCHGLPVENEIDRKLNIKRRDEVIKMGIDKYNEECRSIVTRYVAEWEKVITRCGR 141
Query: 130 SADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVG--YVE 187
D+ +Y TMD + +V + ++K L+YR + + C+T L+ E G Y E
Sbjct: 142 WIDFKNDYKTMDLPFMESVWWVFSQLWEKNLVYRGFKVMPYSTGCKTPLSNFEAGQNYKE 201
Query: 188 EEGYLYYIKLPL---ADGSGYIPIATTRPELMPACVAVFVH 225
+ P+ D + ++ TT P +P+ +A+ V+
Sbjct: 202 VPDPEIMVTFPVIGDQDNAAFVAWTTT-PWTLPSNLALCVN 241
>sp|Q04462|SYV_RAT VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|484949|pir||PN0473 valine--tRNA ligase (EC 6.1.1.9)
- rat (fragment) >gi|207625|gb|AAA42320.1| (M98327)
transfer RNA-Val synthetase [Rattus norvegicus]
Length = 594
Score = 194 bits (487), Expect = 5e-48
Identities = 172/582 (29%), Positives = 255/582 (43%), Gaps = 68/582 (11%)
Query: 184 GYVE--EEGYL--YYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLVGKKV 239
GY E E G L + K+ +D + +ATTR E M VAV VHP D RY+HL GK V
Sbjct: 8 GYKEKVEFGVLVSFACKVQGSDSDEEVVVATTRIETMLGDVAVAVHPKDPRYQHLKGKSV 67
Query: 240 KLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNEN 299
P R +PI+ D+ VD FGTGAV D+ D +R+ L I ++ G +
Sbjct: 68 VHPFLSRSLPIVFDDFVDMEFGTGAVKITPAHDQNDYEVGQRHRLEAISIMDSKGALVNV 127
Query: 300 AGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIR 359
P+ GL EARK + L++ G L++ K V+ RS + +E L + QW++R
Sbjct: 128 PPPFLGLPRFEARKAVLAALKEQG-LFRGVKDNPMVVPLCNRSKDV--VEPLLRPQWYVR 184
Query: 360 VKDFTD--EIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFP-FWVCKNG 416
+ ++ PE W +++ DW ISRQ +G P +++ +
Sbjct: 185 CGEMAQAASAAVTRGDLRILPEAHQRTWHSWMDNIR-DWCISRQLWWGHRIPAYFITVHD 243
Query: 417 HIIPAREED---LPVDPRFDKPPVEKCP-VCGAEIEPVT-----DVLDCWVDSSITPLII 467
+P E+ V R + EK G + ++ DVLD W S + P I
Sbjct: 244 PAVPPGEDPDGRYWVSGRTEAEAREKAAREFGVSPDKISLQQDEDVLDTWFSSGLFPFSI 303
Query: 468 TRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVING 527
W E F +P L G DI+ W + KLTGK P++++ ++
Sbjct: 304 FGW----PNQSEDLSVF---YPGTLLETGHDILFFWVARMVMLGLKLTGKLPFREVYLHA 356
Query: 528 MVAGPDGRKMSKSYGNVVAPDEV------------------------------------- 550
+V GRKMSKS GNV+ P +V
Sbjct: 357 IVRDAHGRKMSKSLGNVIDPLDVIHGVSLQGLHDQLLNSNLDPSEVEKAKEGQRADFPAG 416
Query: 551 IPKYGADALRL-WTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHI-KDFDYEKY 608
IP+ G DALR A G D + F K+WN +FA R + K F
Sbjct: 417 IPECGTDALRFGLCAYTSQGRDINLDVNRILGYRHFCNKLWNATKFALRGLGKGFVPSPT 476
Query: 609 KDIELEP--LDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYR 666
E +DRWI SRL ++ + E + Y F +T +F +E+ D Y+E +K
Sbjct: 477 SKPEGHESLVDRWIRSRLAEAVRLSNEGFQAYDFPAVTTAQYSFWLYELCDVYLECLKPV 536
Query: 667 LYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAM 708
L G D+ + A+ LY L + LL+PF+P +TEE++ +
Sbjct: 537 LNGVDQVAADCARQTLYTCLDVAVRLLSPFMPFVTEELFQRL 578
>sp|O51267|SYL_BORBU LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437538|pir||C70131 leucine--tRNA ligase (EC
6.1.1.4) leuS - Lyme disease spirochete
>gi|2688147|gb|AAB91495.1| (AE001135) leucyl-tRNA
synthetase (leuS) [Borrelia burgdorferi]
Length = 840
Score = 193 bits (486), Expect = 6e-48
Identities = 216/881 (24%), Positives = 346/881 (38%), Gaps = 262/881 (29%)
Query: 5 KYDPNEIEPKWQKYWLEEKIYKYRLDENKPS----YAIDTPPPFTSGTLHLGHVLSHTWI 60
KY+ +IE KWQ++W K YK D + P Y +D P ++ LH+GH +T
Sbjct: 3 KYEFIKIEKKWQEFWDNNKTYKVEEDPSIPKEKRLYILDMFPYPSANGLHVGHPEGYTAT 62
Query: 61 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGI-TKDQPEEFLKKCVEWTWQAIEA 119
DI RYK + G++VL P GFD+ GLP E + I T P++ T + I
Sbjct: 63 DIFGRYKLLNGFHVLHPIGFDSFGLPAE-----NYAIQTGTHPQKS-------TEENINK 110
Query: 120 MRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLA 179
+KQ +G++ DWD E T ++ Y Q L+ YKKGL Y +E PV++CP+ T LA
Sbjct: 111 FKKQIKALGFAYDWDREIRTHEENYYKWTQWIFLQLYKKGLAYVKEMPVWYCPELGTVLA 170
Query: 180 -----------KAEVG-YVEEEGYLYY--------------------------------- 194
K+E G Y E+ YL
Sbjct: 171 NEEIIQTSDGPKSERGSYSVEKKYLRQWVLKITKYAERLLDDLEELEWPESVKEMQRNWI 230
Query: 195 -------IKLPLADGSGYIPIATTRPELMPACVAVFVHPDDE--------RYKHLVGKKV 239
I+ + S I + TTRP+ + + + P+++ +K V K V
Sbjct: 231 GKSTGVEIEFEIEGHSDKIKVFTTRPDTIFGITYLVIAPENKLIEKITKNNFKQNVLKYV 290
Query: 240 KL---------------------------PIYEREVPILADEDVDPNFGTGAVYNCTYGD 272
K PI ++PI V +GTGAV D
Sbjct: 291 KHEELKSDLNRTSLEKDKSGVFTGSYAFHPITNEKIPIWVGSYVLGTYGTGAVMGVPAHD 350
Query: 273 EQDIVWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIK 332
E+D + K+Y L ++ I++ G K E K +D G+
Sbjct: 351 ERDFQFAKKYQLKILPVISKSG------------KNEILEKAFVDD----GI-------- 386
Query: 333 HRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDMFLRLKDWAESM 392
S +P E K + D+++K + E + +L+DW
Sbjct: 387 ----------SINSPNEFNNLKN-----SEVKDKVIKWLTKNKKGKEKVAYKLRDW---- 427
Query: 393 DWDWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTD 452
+ SRQR +G P P K G+ IP E DLP+ P + G P++
Sbjct: 428 ----IFSRQRYWGEPIPILFDKLGNAIPLEENDLPLK----LPEIANYKPSGTGESPLSR 479
Query: 453 VLDCWV---DSSITPLIIT------------RWHEAIKGDEEA-KKWFEHNFPTALRPQG 496
+ D WV D T T R+ + E A KK E+ P L G
Sbjct: 480 IKD-WVNVKDMGFTRETNTMPQWAGSCWYYLRYLDPKNSKEFANKKKIEYWMPVDLYIGG 538
Query: 497 TDIIRTWAFYT------IFRTFKLTGKKPWKDIVINGMVAG-----------PDGR---- 535
+ Y+ ++ + K+P+K ++ G++ P+ +
Sbjct: 539 AEHTVLHLLYSRFWHKVLYDLGYVNTKEPFKKLINQGIITSFSYQKENGVLIPNDQVIEK 598
Query: 536 ------------------KMSKSYGNVVAPDEVIPKYGADALRLWTA-LAPPGEDHPFKW 576
KMSKS NV+ PD++I ++GAD++R++ + P + P+
Sbjct: 599 DNKFFDKKDNKEVTQVIAKMSKSLKNVINPDDIIKEFGADSMRIYEMFMGPLTDSKPWNT 658
Query: 577 ETVDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELE 636
+ + FRFL K+WN+ + K++ E R I+S LH++IK TE+ E
Sbjct: 659 KGIIGVFRFLNKIWNL--------------REKELSKENPPREIISELHKVIKKVTEDTE 704
Query: 637 RYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPF 696
+ FN +M FI E++KY E++ L + +++L+P+
Sbjct: 705 KLNFNTAISAMMIFI--------NELLKY------EKNYL-------NIFKPFIIILSPY 743
Query: 697 VPHITEEIYH------AMFKDKIGEKSVHLLSWPEYREDRI 731
PH+ EE++ ++FK+ WP++ E I
Sbjct: 744 APHLAEELWEYIGELPSLFKNS---------KWPKFDESLI 775
>pir||T41201 isoleucyl-trna synthetase - fission yeast (Schizosaccharomyces
pombe) >gi|5701963|emb|CAB52155.1| (AL109736)
isoleucyl-trna synthetase [Schizosaccharomyces pombe]
Length = 973
Score = 192 bits (484), Expect = 1e-47
Identities = 210/846 (24%), Positives = 344/846 (39%), Gaps = 116/846 (13%)
Query: 19 WLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRMRGYNVLFPQ 78
W +E + K + S+ + PPF +G LH+GH L+ DII R++ ++G +V +
Sbjct: 69 WQKENLNK------EDSFVLLDGPPFANGRLHIGHALNKILKDIINRWQLLKGRSVHYVP 122
Query: 79 GFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMRKQFIRIGYSADWDLEYH 138
G+D HGLP E K K K E K ++ A++ F R+ DW Y
Sbjct: 123 GWDCHGLPIESKAIKANAERKSSLE-IRKIAKDFANSAVQEQLMMFQRMAVMGDWPSRYI 181
Query: 139 TMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVGYVEEE-GYLYYIKL 197
TM D ++ A K L +K LI+R+ PVYW R++LA++E+ Y + Y
Sbjct: 182 TMSDKFEIAELKVFLSLLQKDLIFRQNKPVYWSSSSRSALAESEIEYDDNHVSTSIYFTF 241
Query: 198 PL----ADGSGYIPIA----TTRPELMPACVAVFVHPDDE--RYKH-------------- 233
P+ DG Y + TT P +P+ +A+ HP+ Y+H
Sbjct: 242 PVNSFSIDGCEYNNVKALVWTTTPWTIPSNLALSYHPEINYGLYQHNNSIYLMSDNLVPN 301
Query: 234 ---LVGKK---------VKLPIYE------REVPILADEDVDPNFGTGAVYNCTYGDEQD 275
+ G K + YE + P L V + GTG V+ +D
Sbjct: 302 LDFMQGAKRLASCPSDIISSFTYENPLLPKQSFPFLQSNYVTNDIGTGIVHVAPGHGMED 361
Query: 276 IVWQKRYNLPVIIAINEDGTMNENA--GPYAGLKV-EEARKKIAEDLEKMGLLYKKEKIK 332
+ NL +++ G + A G GL+V + KK+ ++ ++ K K
Sbjct: 362 YLLGLENNLRPFSPLDDYGRYTKEALDGSLEGLEVLGDGGKKVISIMKNQNMIVKVSPYK 421
Query: 333 HRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDMFLRLKDWAESM 392
H R+ P+ L QWFI +++ +K + P + RL +
Sbjct: 422 H---RYPYDWRTHKPLILRATPQWFISLENERKTAIKALDSVKMIPPNSRARLLGFLNGR 478
Query: 393 DWDWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEI---EP 449
+W ISRQR +G P P + + G IP + + +EK V G + +
Sbjct: 479 P-EWCISRQRAWGLPIPV-LYEKGTKIPL------LTVKSVSYIIEKMEVEGVDSWFNDT 530
Query: 450 VTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFP-TALRP-----------QGT 497
+ WV R E I+G E WF+ T + P +G+
Sbjct: 531 ENNGHAQWVHPDY------RNKEYIRGTETLDVWFDSGTSWTTIAPRKNKPLIDLCLEGS 584
Query: 498 DIIRTWAFYTIFRTFKLTGKK---PWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIP-- 552
D R W F ++ T+ K P+ + +G + G+K SKS GNV P++VI
Sbjct: 585 DQHRGW-FQSLLLTYTAYQSKPEAPFSTLFTHGFIFDERGQKQSKSLGNVTDPEDVINGK 643
Query: 553 -------KYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDFDY 605
YG D LRLW A D + L+K RF ++ D++
Sbjct: 644 LLKGKKLPYGVDLLRLWVASCDSTNDTNLGPNILTQVGESLKKWRLTSRFCLGNLHDWNT 703
Query: 606 EKYKDI-ELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVK 664
D+ EL +D+ L +L + E E Y N + L F+ ++ Y + VK
Sbjct: 704 SSSVDVGELRGIDKLALVQLDKFQTEIRELYESYSINKVVHHLNYFMNSFLSSTYFDAVK 763
Query: 665 YRLYGD--DEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAM--------FKDKIG 714
RLY D + S+ + LY L ++ ++P P + +EI+ ++ ++
Sbjct: 764 DRLYADLPNSVSRRSVQTVLYHSLLTLIWAISPITPLLAQEIWQSLPDSYLNSSYQTPFH 823
Query: 715 EKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAI-YALE 773
HL+S + D +D K K +++ K S + + A E++ I +LE
Sbjct: 824 AGETHLISSLRSKVDLLDRK------FLIKEYLVLQQLKYSINLLITAARENLTIKNSLE 877
Query: 774 SYDDLK 779
+Y +K
Sbjct: 878 AYVVIK 883
>pir||T19442 hypothetical protein C25A1.7a - Caenorhabditis elegans
>gi|3874441|emb|CAB02766.1| (Z81038) predicted using
Genefinder~Similarity to Yeast isoleucyl-tRNA synthetase
(SW:P48526), contains similarity to Pfam domain: PF00133
(tRNA synthetases class I (I, L, M and V)), Score=424.2,
E-value=3.8e-124, N=1~cDNA EST yk408e2.3 comes from this>
Length = 1131
Score = 191 bits (480), Expect = 3e-47
Identities = 209/926 (22%), Positives = 369/926 (39%), Gaps = 137/926 (14%)
Query: 42 PPFTSGTLHLGHVLSHTWIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQ 101
PP+ +G H GH ++ D + + + GY VLF G+D HGLP ELK+ K+ G +
Sbjct: 183 PPYANGEAHTGHAINKILKDFVVKSRIALGYRVLFRPGWDCHGLPIELKIGKQQGNAGSR 242
Query: 102 -PEEFLKKCVEWTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGL 160
P E +AI F R G +ADW+ Y T Y AA + ++ L
Sbjct: 243 TPLETRAAARIVADEAIGKQMNAFRRWGVTADWEKPYVTKSPSYVAAQLDIFAKLVEQKL 302
Query: 161 IYREEHPVYWCPKCRTSLAKAEVGYVEE-EGYLYYIKLPLADGSG--------------- 204
+YR PVYW P T+LA++E+ Y ++ + Y + L + S
Sbjct: 303 VYRSFKPVYWSPSSNTALAESELEYNDKHQSTSAYFRFKLINFSSSDVIWAHSEPSKISQ 362
Query: 205 -YIPIATTRPELMPACVAV----------------------------------FVHPDDE 229
+ I TT P +P A+ F D
Sbjct: 363 FFALIWTTTPWTLPLNNAISVSSAIQYSLIQFDNEINNPTSTFYVIASKLLEEFQKSSDR 422
Query: 230 RYK--------HLVGKKVKLPIY-EREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQK 280
+ K +L+G++ K + E +PI V GTG V+ QD
Sbjct: 423 KCKVVGTVKPANLIGRRYKSCWHNELGLPIYEGPHVTDTVGTGLVHTAFAHGFQD----- 477
Query: 281 RYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTE 340
Y++ + + ++ L + K++ + +K+ L I H V +H
Sbjct: 478 -YDVAISKGDRVESFVDSRGCYTRHLGHDLDGKEVLGEGQKIALRLLNHDIVH-VSKHVH 535
Query: 341 RSS----CMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDMFLR--LKDWAESMDW 394
P+ + +QWFI V + + +I+ D LR LK +
Sbjct: 536 SYPYDWRTKKPVIIRSSEQWFIDVDEIGKRASMMLDDISVAAGDSDLRASLKQLVTTRK- 594
Query: 395 DWVISRQRVFGTPFPFWVCKNGHIIPARE------------------EDLPVDPRFDKPP 436
W ISRQRV+GTP P V NG +R+ ++ V +
Sbjct: 595 SWCISRQRVWGTPIPALVDDNGGSYTSRKLIEWVAKLTRERENTDVWWEIDVKEILENEE 654
Query: 437 VEKCPVCGAEI----EPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTAL 492
V + ++I + TD++D W+DS + WH A D E EH L
Sbjct: 655 VRRSLEIPSDIVSQLKKNTDIMDVWLDSGLA------WHAARDNDTER----EHVADVVL 704
Query: 493 RPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVI- 551
+G D R W + + + K P+K I+++G + KMSKS GNVV P +
Sbjct: 705 --EGVDQFRGWFQSLLLTSVAVQNKLPYKKIIVHGFCIDENNNKMSKSIGNVVDPTMLTD 762
Query: 552 -----PKYGADALRLWTAL--APPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDFD 604
GAD LR W AL + + + +D + + N +RF + FD
Sbjct: 763 GSLKQKAIGADGLRFWVALSGSENAGESKIGMKIIDDVDKKVIAFRNGFRFMIGGCQGFD 822
Query: 605 YEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVK 664
++ K L+ LD +L I+K + ++F + +L F+ + +Y++ V+
Sbjct: 823 GKQVK-FPLKTLDIDMLQNCDAIVKRSIVNYNDFKFRTVANDLTQFLQRNFSANYVKYVR 881
Query: 665 YRLYGD--DEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLS 722
RLY D ES + A+ L+ L +N+ +++P +PH++ E+ + EK + L
Sbjct: 882 DRLYCDKVGSESHISAQFTLHRLAHNLAHIISPILPHLSSEVLQHL--PGSHEKQILRLK 939
Query: 723 WPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESYDD-LKLI 781
+ + + ++L + + V +++ G ++ + + + Y L++
Sbjct: 940 FEDLHYGLLTPH-DQLSKHMKFVYEVRNLLESTAGPKIDTSKKGIVLQVTPEYHTILRIY 998
Query: 782 EKDIAGTMNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKNNAESIAR 841
E ++ +N+ ++ + + + +VE + Y R +H +N ++++
Sbjct: 999 ESELPELLNVSQVILHENRDENSVELVESRLRY----------CERCRKHTRNESDALCG 1048
Query: 842 EIKEN---GKVEFEIDGEKVELTKED 864
+ + F +K +L K+D
Sbjct: 1049 RCSDAMGLSRATFSRSVQKQDLRKQD 1074
>sp|P56457|SYL_HELPY LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437532|pir||C64713 leucine--tRNA ligase (EC
6.1.1.4) - Helicobacter pylori (strain 26695)
>gi|2314727|gb|AAD08585.1| (AE000652) leucyl-tRNA
synthetase (leuS) [Helicobacter pylori 26695]
Length = 806
Score = 188 bits (473), Expect = 2e-46
Identities = 191/820 (23%), Positives = 324/820 (39%), Gaps = 216/820 (26%)
Query: 11 IEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRMR 70
IE KWQ++W + K ++ + D N P I + P+ SG +H+GHV ++T D +ARY R+
Sbjct: 6 IEKKWQEFWWKNKSFEPKDDFNLPKKYILSMLPYPSGEIHMGHVRNYTIGDALARYYRLH 65
Query: 71 GYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMRKQFIRIGYS 130
YNVL P GFD+ G+P E K GI P+ WT++ IE M+K+F +G+S
Sbjct: 66 HYNVLHPMGFDSFGMPAENAAIKH-GI---HPK-------TWTYENIENMQKEFEALGFS 114
Query: 131 ADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV------- 183
+ E+ T D Y Q+ ++ ++KGLIYR++ + WCP +T LA +V
Sbjct: 115 FSKNREFATSDPDYTKFEQRFFIDLWEKGLIYRKKAMLNWCPNDKTVLANEQVIDGRCWR 174
Query: 184 ---GYVEEEGYLYYIK-------------------------------------------- 196
+++E Y YY+K
Sbjct: 175 CDTEVIQKELYQYYLKITNYAEELLKDLEALEDHWPSQVLIMQKNWIGKSSGLQFGFKIA 234
Query: 197 ---LPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHL-------VGKKVK------ 240
L +G I + TTR + + + + P+ +H V K +K
Sbjct: 235 DECLKACNGIQEIEVFTTRADTIYGVTYIAIAPEHPLVEHAIKQVSQEVSKMIKAILNTT 294
Query: 241 ------------LPIY------EREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRY 282
L IY ++++P+ N+G+GA+ DE+D + Y
Sbjct: 295 QRERALEKKGAFLGIYAIHPLTKQKIPVWVANFALANYGSGALMGVPACDERDFEFANLY 354
Query: 283 NLPVIIAINEDGTMN-------ENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRV 335
++P+ + + +N+G ++ L AR++I ++KE + RV
Sbjct: 355 HIPIKVITQSPQNLPHTKEEVLKNSGEWSDLSSSVAREQII-------AYFEKENLGKRV 407
Query: 336 LRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWD 395
+ + RL+DW
Sbjct: 408 INY---------------------------------------------RLQDWG------ 416
Query: 396 WVISRQRVFGTPFPFWVCKNGHIIPARE------EDLPVDPRFDKPPVEK--------CP 441
+SRQR +G P P C + I+P + ED+ +D + P+EK CP
Sbjct: 417 --VSRQRYWGAPIPMIHCNHCGIVPETQLPVTLPEDIVIDG--EGNPLEKHASWKFTQCP 472
Query: 442 VCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIR 501
C TD +D ++ SS L T + + + ++ P G +
Sbjct: 473 KCHKNALRETDTMDTFIQSSWYFLRYTTPKNQRENQAFDQNYLKYFMPVDTYIGGIEHAI 532
Query: 502 TWAFYTIFRTFKLTG------KKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYG 555
Y F T L +P+K ++ GMV +G KMSKS GNVV+P E++ KYG
Sbjct: 533 LHLLYARFFTKALRDLGYLHLDEPFKQLITQGMVL-KNGAKMSKSKGNVVSPKEILKKYG 591
Query: 556 ADALRLWTAL-APPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIELE 614
ADA RL+ APP ++ + ++ RF+++ +Y A ++K++ L
Sbjct: 592 ADAARLFILFAAPPAKELEWNDSALEGAHRFIKR---LYDKANAINPTTSKPEFKEVSLN 648
Query: 615 PLDRWILSRLHRIIKFATEELER----YRFNLITRELMTFIWHEVADDYIEMVKYRLYGD 670
+ +++ +K + E + Y FN + M +
Sbjct: 649 EAQKLGRKKVYEALKKSHEIFNKAESAYSFNTLIASCMEAL------------------- 689
Query: 671 DEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFK 710
+ S + L E + ++ +L P +PH E+ +FK
Sbjct: 690 NALSAQNNERILCEGYFVLLQILEPIIPHTAWELSERLFK 729
>sp|Q9ZCU4|SYI_RICPR ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS)
>gi|7437564|pir||B71667 isoleucine--tRNA ligase (EC
6.1.1.5) (ileS) RP617 - Rickettsia prowazekii
>gi|3861160|emb|CAA15060.1| (AJ235272) PROBABLE
ISOLEUCYL-TRNA SYNTHETASE (ileS) [Rickettsia prowazekii]
Length = 1086
Score = 182 bits (458), Expect = 1e-44
Identities = 192/805 (23%), Positives = 325/805 (39%), Gaps = 118/805 (14%)
Query: 11 IEPKWQKYWLEEKIYKYRLD--ENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKR 68
IE + K+W I++ +D + + PPF +G H GH+L+ D+ ARYK
Sbjct: 19 IEQEILKFWQNNNIFQKSIDYRNGESEFIFYDGPPFANGLPHYGHLLTGFIKDVYARYKT 78
Query: 69 MRGYNVLFPQGFDNHGLPTELKVEKEFGI------TKDQPEEFLKKCVEWTWQAIEAMRK 122
++G V G+D HGLP E++ EKE GI T E+F C Q +
Sbjct: 79 IKGKKVERRFGWDCHGLPAEMQSEKELGISGRIAITNFGIEKFNNHCRASVMQYASEWEQ 138
Query: 123 QFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAE 182
R + Y TMD + +V + E Y K L+Y + + C T L+ E
Sbjct: 139 YVTRQARWVAFKNAYKTMDKNFMESVLWAFKELYNKDLLYESMRVMPYSWACETPLSNFE 198
Query: 183 ----------------VGYVEEEGYLYY----IKLPLADGSGY----IPIATTRPELMPA 218
V +V E L K + +G + I TT P +PA
Sbjct: 199 TRLDNAYRERTDKAITVSFVLNEVTLINGIISQKSDMKEGDNFKEYRILAWTTTPWTLPA 258
Query: 219 CVAVFVHPD-------------------------------DERYKHLVGKKVKLPIYE-- 245
+A+ V D E ++ + G K++ Y+
Sbjct: 259 NLALAVGSDIDYAFVDKNEVCYIIAASSVAKYAKELGLSGKENFEIIKGLKLQGLSYKPL 318
Query: 246 --------REVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMN 297
I A + V GTG V+ E D + + + ++ ++ G
Sbjct: 319 FNYFENHPNSFKIFASDFVVEGDGTGIVHMAPGFGEDDQILCESKGIELVCPVDNSGKFT 378
Query: 298 ENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWF 357
+ G++V +A KI L++ G K E+ H H R+ + +P W+
Sbjct: 379 KEIPDLEGVQVFDANDKIIIKLKEQGNWIKTEQYIHNY-PHCWRTDTPLIYKAVPS--WY 435
Query: 358 IRVKDFTDEIVKVAKEINWYPEDMFLRL-KDWAESMDWDWVISRQRVFGTPFPFWVCKNG 416
+RV F D +V++ ++INW P ++ L W E+ DW ISR R +GTP P W +
Sbjct: 436 VRVTKFKDRMVELNQQINWIPHNVKDNLFGKWLENAR-DWSISRNRFWGTPLPVWKSDDP 494
Query: 417 HI--------IPAREEDLPVDPR-FDKPPVEKC-------PVCGAEIEPVTDVLDCWVDS 460
I E+D V +P +++ P + + + DV DCW +S
Sbjct: 495 KYPRIDVYGSIEEIEKDFGVKINDLHRPFIDELTRTNPDDPTGKSTMRRIDDVFDCWFES 554
Query: 461 SITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPW 520
P + + E KKWF +FP + + R W + + + L + P+
Sbjct: 555 GSMP------YGQVHYPFENKKWFVEHFPADFIVEYSSQTRGWFYTLMVLSTALFDRPPF 608
Query: 521 KDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPP---------GED 571
+ + +G++ G+K+SK N P E+ KYG+DALR+ T L+ +D
Sbjct: 609 LNCICHGVILDATGQKLSKRLNNYADPLELFDKYGSDALRV-TMLSSNVVKGQELLIDKD 667
Query: 572 HPFKWETVDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIELE-PLDRWILSRLHRIIKF 630
++T+ F++ +WN Y F + + + + LD +ILS+L +
Sbjct: 668 GKMVFDTLRL---FIKPIWNAYHFFTIYANADSLKGTLNFASQNVLDVYILSKLKIAVNK 724
Query: 631 ATEELERYRFNLITRELMTFIWHEVADD-YIEMVKYRLYGDDEES-KLKAKVALYELLYN 688
E L+ + + F EV ++ YI + R + +++++ K A LY L
Sbjct: 725 IEESLDNFDTQTAYHAVSEFF--EVLNNWYIRRSRARFWKNEKDTDKQNAYNTLYSCLKI 782
Query: 689 VMLLLAPFVPHITEEIYHAMFKDKI 713
+ + ++ +P I+E IY + I
Sbjct: 783 MTIAMSALIPMISETIYQGLHNTAI 807
>sp|Q9YD97|SYL_AERPE LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437650|pir||H72699 probable leucyl-tRNA synthetase
APE1015 - Aeropyrum pernix (strain K1)
>gi|5104685|dbj|BAA80000.1| (AP000060) 959aa long
hypothetical leucyl-tRNA synthetase [Aeropyrum pernix]
Length = 959
Score = 179 bits (449), Expect = 1e-43
Identities = 239/969 (24%), Positives = 389/969 (39%), Gaps = 162/969 (16%)
Query: 11 IEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRMR 70
+E KWQ+ W E ++++ + + I P P+ + HLG + +DI+ARYKRMR
Sbjct: 7 VEEKWQERWREARLFEADPQPGRRKFFITFPYPYVNAYPHLGSAFTILRVDIMARYKRMR 66
Query: 71 GYNVLFPQGFD-------------NHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAI 117
GYNVLFPQG+ G P +K ++ GI ++ F + W
Sbjct: 67 GYNVLFPQGWHATGGPIVSSALRVREGDPRIIKTLRDMGIPEEDIPRF-RDPRYWVEFFT 125
Query: 118 EAMRKQFIRIGYSADWDLEYHT--MDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCR 175
+A R+ R G S DW E++T ++ Y ++ L+ +KG + + HPV WCPK +
Sbjct: 126 KAWRRDLERYGMSIDWRREFYTTSLNPAYSRFIEWQYLKLREKGFVGKGRHPVVWCPKEQ 185
Query: 176 TSLAKAE-----VGYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPD--- 227
+ + G +E + IK DG Y P T RPE + ++VHPD
Sbjct: 186 KVVGDHDRPDEYAGISPQEAVI--IKFRGRDGLVY-PALTYRPETVFGVTNLWVHPDATY 242
Query: 228 -------DERY-------------------------KHLVGKKVKLPIYEREVPILADED 255
+ER+ + L+G+ V P REVP+L
Sbjct: 243 LVAEVDGEERWIIGEQAARELADQGHRVVILERIEGRRLLGRIVVNPADGREVPVLPASF 302
Query: 256 VDPNFGTGAVYNCTYGDEQDIV----------WQKRYNL-PVIIAINEDGTMNENAGPYA 304
V P+ GTG V + D V + Y L P ++ E +
Sbjct: 303 VRPDLGTGVVMSVPAHAPYDYVALMELKRRPETLREYGLEPGVVESLEPIQLIAVPRAEG 362
Query: 305 GLKVEEARKKIAE---DLEKMG----LLYKKEKIKHRVLRHTERSSCM-------APIEL 350
L VEE R++ E D EK+ +Y +E + +L T R S + +E
Sbjct: 363 LLVVEEVRRRGVESQMDREKLDEATREVYAREFYEGIMLETTGRFSGLKVAEAKEKVVEW 422
Query: 351 LPKKQWFIRVKDFTDEI---------VKVAKEINWY-----PEDMFLRLKDWAESMDW-- 394
L ++ +R+ E+ VK+ ++ W+ PE L ++ M++
Sbjct: 423 LEERGAALRIYTLPQEVYCRCGARTHVKIVED-QWFLLYSKPEWKAL-AREAVARMEFLP 480
Query: 395 ---------------DWVISRQRVFGTPFPF---WVCKNGHIIPAREEDLPVDPRFDKPP 436
DW + + GTP P+ WV ++ + P
Sbjct: 481 GHVRRDFEAIIEALRDWAFTHKGELGTPLPWDREWVIESLSDSTIYMAYYTIAKYTQHP- 539
Query: 437 VEKCPVCGAEIEPVT-DVLDCWVDSSITPLIITRWHEAIKG-DEEAKKWFEHNFPTALRP 494
EK G E E +T +V D + P ++R +G EE ++ F + +P +R
Sbjct: 540 -EK---YGVEPEMLTPEVFDYVFLGAGDPGEVSRRSGIPQGLLEEMRREFLYWYPLDMRI 595
Query: 495 QGTDIIRTWAFYTIFRTFKLTGKKPW-KDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPK 553
G D+I + IF + ++ W + I +NG V G KMSKS GN + + +
Sbjct: 596 SGKDLIPNHLVFFIFHHTAIFPRELWPRAIGVNGWVL-VAGEKMSKSKGNFILLRQALDW 654
Query: 554 YGADALRLWTALAPPG---EDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDFDYEKYKD 610
+GADA R LA +D F+ D L + + R +Y +
Sbjct: 655 WGADATRWAEVLAGADSGLDDANFEPSVADSAVSLLSQWLDFVR--------ENYGRPAR 706
Query: 611 IELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGD 670
E +DRW SRL+ I T +E F + + W+++ + Y ++ R G+
Sbjct: 707 REERWVDRWFESRLNSTIARVTRLMEEANF----KTALVEAWYKLQESYRWYLR-RSGGE 761
Query: 671 DEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYREDR 730
E L+ + + LL+APF PH EE + AM ++ + SWPE E +
Sbjct: 762 PREDLLRRFIEVQ------TLLIAPFAPHTAEEAWEAMGREGFASTA----SWPEPDESK 811
Query: 731 IDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESYDDLKLIE--KDIAGT 788
I + E E + V+ + R+ + G A V + A Y ++ + ++ +
Sbjct: 812 ISPEVEAAEETVQAVLEDAREVLSLIG---GADTLVVTVAAEWKYRAVEAVRRARERGAS 868
Query: 789 MNIEKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIV--EHLKNNAESIAREIKEN 846
M E FK E + + R + PR V E L++ A+ + E+
Sbjct: 869 MKEALREAFKVEGVDKREAARLVQQLSRAPEVLRRAAPRSVELEALRDAAQLLQEELGVK 928
Query: 847 GKVEFEIDG 855
VE E DG
Sbjct: 929 VVVETEEDG 937
>sp|P46216|SYV_TRIVA VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|598414|gb|AAC41565.1| (L37098) valyl-tRNA synthetase
[Trichomonas vaginalis]
Length = 489
Score = 176 bits (443), Expect = 7e-43
Identities = 141/503 (28%), Positives = 226/503 (44%), Gaps = 54/503 (10%)
Query: 81 DNHGLPTELKVEKEFGITKD------QPEEFLKKCVEWTWQAIEAMRKQFIRIGYSADWD 134
D+ G+ T+ +VEK+ K E FL++ +W + Q +G S W
Sbjct: 1 DHAGIATQFRVEKKIYDEKKLHRGEYSREYFLEEAHKWVESKSGTILSQLRDMGSSLAWK 60
Query: 135 LEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEVGYVE------- 187
Y+T+D+ +V + ++ + +GLIYR E V W +T+++ AEV Y+
Sbjct: 61 DTYYTLDEKLSESVIAAFIKLFDEGLIYRSERLVNWDCALKTAISDAEVEYITLTKRTKL 120
Query: 188 ----------EEGYLYYIKLPLADGSG-----YIPIATTRPELMPACVAVFVHPDDERYK 232
G + + + D G + IATTR E M AV ++P D RY
Sbjct: 121 NVPNHKYPQYPFGVMAHFYYEICDKDGKKTGEKVEIATTRLETMLGDTAVAINPKDARYN 180
Query: 233 HLVGKKVKLPIYEREVPILADED-VDPNFGTGAVYNCTYGDEQDI-VWQKRYNLPVIIAI 290
HL G V PI E +PI+ DE VD NFGTG V D D V+++ + +I +
Sbjct: 181 HLHGMYVWHPIREVPIPIIQDEILVDMNFGTGVVKVTPGHDPNDYEVYKRHPEIGLISIL 240
Query: 291 NEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIEL 350
DG + G ++G+ +AR ++ + +++ G LYK+EK L T+R + +E
Sbjct: 241 TPDGAIAPGYGQFSGMMRFDARVEMVKWMKEHG-LYKEEKDHEMRLGITQRGHDI--VEQ 297
Query: 351 LPKKQWFIRVKDFTDEIVKVAK--EINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPF 408
+ QWF+ D +K E+ P++ + K W E++ W ISRQ ++G
Sbjct: 298 VITPQWFVNTTDMAARAIKAVDDGELKIVPDEFVVDWKKWHENIR-PWCISRQLMWGLRI 356
Query: 409 PF--------WVCKNGHIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDCWVDS 460
P W NG + A ++ + V V +E DVLD W S
Sbjct: 357 PAYRVQIDGKWAEGNGEWVAAASQEEAIAKGAKANNVVPSRV---TVEQDPDVLDTWFSS 413
Query: 461 SITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPW 520
++ P W +E ++ FP ++ G DI+ W + + LT K P+
Sbjct: 414 ALLPFSGVGWP---SNEERLNRY----FPNSILETGWDILTFWVSRMVMMSLTLTNKVPF 466
Query: 521 KDIVINGMVAGPDGRKMSKSYGN 543
I+++ +V GRKMSKS+GN
Sbjct: 467 HTILLHPLVRDAQGRKMSKSFGN 489
>gb|AAD36946.1|AF069441_6 (AF069441) putative leucyl tRNA synthetase [Arabidopsis thaliana]
>gi|7267192|emb|CAB77903.1| (AL161500) putative leucyl
tRNA synthetase [Arabidopsis thaliana]
Length = 973
Score = 174 bits (436), Expect = 5e-42
Identities = 210/887 (23%), Positives = 330/887 (36%), Gaps = 273/887 (30%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYR--LDENKPSYAIDTPPPFTSGT-LHLGHVLSHT 58
L + Y +EIEPKWQ+YW + +I++ +D +KP + + P+ SG LH+GH L +T
Sbjct: 81 LKRVYPFHEIEPKWQRYWEDNRIFRTPDDVDTSKPKFYVLDMFPYPSGAGLHVGHPLGYT 140
Query: 59 WIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGI-TKDQPEEFLKKCVEWTWQAI 117
DI+AR +RM+GYNVL P G+D GLP E ++ I T P+ T + I
Sbjct: 141 ATDILARLRRMQGYNVLHPMGWDAFGLPAE-----QYAIETGTHPKTT-------TLKNI 188
Query: 118 EAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTS 177
+ R Q +G+S DWD E T + Y Q L+ YKKGL Y+ E PV WCP T
Sbjct: 189 DRFRLQLKSLGFSYDWDRELSTTEPDYYKWTQWIFLQLYKKGLAYQAEVPVNWCPALGTV 248
Query: 178 LAKAE-VGYVEEEGYLYYIKLP-------------------------------------- 198
LA E V V E G I+ P
Sbjct: 249 LANEEVVDGVSERGGHPVIRKPMRQWMLKITAYADRLLEDLDELEWPESIKEMQRNWIGR 308
Query: 199 ---------LADGSG-----YIPIATTRPELMPACVAVFVHPDD---------------E 229
+ DG G I + TTRP+ + + V P+ E
Sbjct: 309 SEGAELNFSILDGEGRETDKEITVYTTRPDTLFGATYMVVAPEHQLLSYFVTAEQKQQVE 368
Query: 230 RYKHLVGKK--------------------VKLPIYEREVPILADEDVDPNFGTGAVYNCT 269
YK +K K P +PI + V ++GTGA+
Sbjct: 369 EYKDFASRKSDLERTELQKDKTGVFTGCYAKNPANGDAIPIWVADYVLASYGTGAIMAVP 428
Query: 270 YGDEQDIVWQKRYNLPVIIAINEDGTMNENAGP-YAGLKVEEARKKIAEDLEKMGLLYKK 328
D +D + +YN+P+ + + +++A Y GL + E + L+
Sbjct: 429 AHDTRDNEFALKYNIPIKWVVRNEANSSDDAKQVYPGLGIIENSSTLETGLD-------- 480
Query: 329 EKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDMFLRLKDW 388
I L K+ ++V ++ + K++N+ +L+
Sbjct: 481 -------------------INQLSSKEAALKVIEWAERTGNGKKKVNY-------KLR-- 512
Query: 389 AESMDWDWVISRQRVFGTPFPFWVC-KNGHIIPAREEDLPVD-PRFD--------KPPVE 438
DW+ +RQR +G P P + ++G I E +LP+ P + +PP+
Sbjct: 513 ------DWLFARQRYWGEPIPILILDESGETIAISESELPLTLPELNDFTPTGTGEPPLS 566
Query: 439 KC--------PVCGAEIEPVTDVLDCWVDSS--ITPLIITRWHEAIKGDEEAKKWFEHNF 488
K P G + T + W S + + EA+ E+ K W
Sbjct: 567 KAVSWVNTVDPSTGKPAKRETSTMPQWAGSCWYYLRFMDPKNPEALVDKEKEKYW----S 622
Query: 489 PTALRPQGTDIIRTWAFYT------IFRTFKLTGKKPWKDIVINGMVAG----------- 531
P + G + Y+ ++ ++ K+P+K ++ G++ G
Sbjct: 623 PVDVYVGGAEHAVLHLLYSRFWHKVLYDIGVVSTKEPFKCVINQGIILGEVQYTAWKDQE 682
Query: 532 -------------------------------------PDGRKMSKSY------GNVVAPD 548
P R + + Y GNVV PD
Sbjct: 683 GNYVSADTEERLNEHQQVTIPEEKVIKSGDHFVLKEDPSIRLIPRVYKMSKSRGNVVNPD 742
Query: 549 EVIPKYGADALRLWTALAPPGEDHPFKWET--VDYNFRFLQKVWNI---YRFAERHIKDF 603
+V+ +YGAD+LRL+ P D W T ++ RFL + W + ++ KD
Sbjct: 743 DVVLEYGADSLRLYEMFMGPFRDSK-TWNTSGIEGVHRFLARTWRLVIGLPQSDGSFKDG 801
Query: 604 DYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFI-----WHEVADD 658
+ LE L LH+ I TEE+E RFN +M F+ W+
Sbjct: 802 TLVTDDEPTLEQ-----LRTLHKCIAKVTEEIESTRFNTGISGMMEFVNAAYKWNNQPRG 856
Query: 659 YIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIY 705
IE +LLL+P+ PH+ EE++
Sbjct: 857 IIE--------------------------PFVLLLSPYAPHMAEELW 877
>dbj|BAB07000.1| (AP001518) leucyl-tRNA synthetase [Bacillus halodurans]
Length = 806
Score = 173 bits (433), Expect = 1e-41
Identities = 215/860 (25%), Positives = 332/860 (38%), Gaps = 220/860 (25%)
Query: 6 YDPNEIEPKWQKYWLEEKIYKYRLDENKPS-YAIDTPPPFTSGTLHLGHVLSHTWIDIIA 64
+ EIE KWQKYW E K +K DE + YA+D P + LH+GH +T DI++
Sbjct: 3 FSHREIESKWQKYWEENKTFKTEEDETREKFYALDMFPYPSGAGLHVGHPEGYTATDILS 62
Query: 65 RYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGI-TKDQPEEFLKKCVEWTWQAIEAMRKQ 123
R KRM+GYNVL P G+D GLP E ++ I T + P EF +K I R+Q
Sbjct: 63 RMKRMQGYNVLHPMGWDAFGLPAE-----QYAIDTGNSPAEFTEK-------NINTFRRQ 110
Query: 124 FIRIGYSADW-------DLEYHTMDDWYKAAVQKSLLEFYKK------------------ 158
+G+S DW D +Y+ W + L + +
Sbjct: 111 IKSLGFSYDWDREVNTTDPDYYKWTQWIFIQLYNKGLAYIDEVAVNWCPALGTVLANEEV 170
Query: 159 --GLIYREEHPV------YWCPKCRTSLAKAEVGYVEEEGYLYYIK------LPLADGSG 204
G R HPV W K T A + +EE + IK + ++G+
Sbjct: 171 IDGKSERGGHPVERRPMKQWMLKI-TEYADRLLEDLEELDWPESIKDMQRNWIGRSEGAE 229
Query: 205 Y----------IPIATTRPELMPACVAVFVHPDD---------------ERYKHLVGKKV 239
I + TTRP+ + + + P+ E YK V K
Sbjct: 230 VTFSVDGHDDTITVFTTRPDTLFGATYMVLAPEHKLVDAITTSEQKQAVESYKKEVATKS 289
Query: 240 KL--------------------PIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQ 279
L P+ +VPI + V ++GTGA+ DE+D +
Sbjct: 290 DLERTELAKEKTGVFTGAYAINPVNGEKVPIWIADYVLVSYGTGAIMAVPAHDERDYEFA 349
Query: 280 KRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHT 339
K ++LP+ ++ G + + A G V E + L K+E I+ +
Sbjct: 350 KTFDLPIKEVVS-GGVIEQEAYTGDGPHVNS---------EFLNGLSKEEAIEKMI---- 395
Query: 340 ERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVIS 399
QW K T ++ RL+DW + S
Sbjct: 396 ---------------QWLEAEKKGTKKVT--------------YRLRDW--------LFS 418
Query: 400 RQRVFGTPFPFWVCKNGHIIPAREEDLPVD-PRFD--KP------PVEKC--------PV 442
RQR +G P P ++G + E++LP++ P+ KP P+ PV
Sbjct: 419 RQRYWGEPIPVIHWEDGTMSTVPEDELPLELPKMSEIKPSGTGESPLANATDWLEVVDPV 478
Query: 443 CGAEIEPVTDVLDCWVDSSITPL--IITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDII 500
G + T+ + W S L I I E+ KKW P + G +
Sbjct: 479 TGKKGRRETNTMPQWAGSCWYYLRYIDPDNERMIADPEKLKKWL----PVDIYIGGAEHA 534
Query: 501 RTWAFYT------IFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKY 554
Y ++ + K+P++ + GM+ G + KMSKS GNVV PD++I +
Sbjct: 535 VLHLLYARFWHKVLYDLGVVPTKEPFQKLYNQGMILGENNEKMSKSKGNVVNPDDIIDSH 594
Query: 555 GADALRLWTALAPPGEDHPFKWET--VDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIE 612
GAD LRL+ P D W T +D RFL +VW + + + EK I
Sbjct: 595 GADTLRLYEMFMGP-LDASIAWSTTGLDGARRFLDRVWRLL------VDENTEEKSSKIV 647
Query: 613 LEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDE 672
+ H+ +K TE+ E RFN+ +LM ++ + + + D
Sbjct: 648 NGEGSPELKRAYHQTVKKVTEDFEELRFNVGISQLMVYVNEAYKQEELPL-------DQA 700
Query: 673 ESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIG-EKSVHLLSWPEYR---- 727
E +K LL+P PH+ EE++ K+G E ++ WP Y
Sbjct: 701 EGFVK--------------LLSPVAPHLAEELW-----SKLGHEGTIAYEPWPTYDEAFL 741
Query: 728 -EDRIDEKAEKLGELARKVV 746
ED ++ + G++ KVV
Sbjct: 742 VEDEVEIVVQHNGKVRAKVV 761
>emb|CAC11908.1| (AL445065) leucyl-tRNA synthetase related protein [Thermoplasma
acidophilum]
Length = 910
Score = 170 bits (427), Expect = 5e-41
Identities = 201/841 (23%), Positives = 349/841 (40%), Gaps = 161/841 (19%)
Query: 10 EIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRM 69
+IE KWQ W + I+ ++D K + I P P+T+G+LH+GH ++T DIIARYKR
Sbjct: 18 DIEAKWQNAWDRDGIFVPKMDGRK-KFMITVPWPYTNGSLHVGHGRTYTLGDIIARYKRS 76
Query: 70 RGYNVLFPQGFDNHGLPT---ELKVEKEFGITKDQPEEFLKKCVEWTWQAI--------- 117
R YNVLFP GF G P ++ T D +LK+ E A+
Sbjct: 77 RNYNVLFPMGFHQSGTPILAFSERIRAGDRSTIDLYTSYLKEYGEKDIDALIESFKDPKN 136
Query: 118 ------EAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWC 171
A+ F +GYS DW + + D++Y+ VQ +KGL+ + +P+ +
Sbjct: 137 IADYFSNAIINDFKHLGYSIDWTRRFTSADEFYQKFVQWQFRRLNEKGLVKQGRYPILYS 196
Query: 172 PKCRTSLAKAEV--GYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPDDE 229
+ ++ + ++ G ++ Y + S + A+ RPE + ++V+PD +
Sbjct: 197 LEDDNAVGEDDIKDGDTDKVTIEEYTAIFFRGKSFDLIAASLRPETIYGITNIWVNPDVK 256
Query: 230 RYKHLVGKKVKLPIYE---------------------------------REVPILADEDV 256
K + ++ + E +EV + + V
Sbjct: 257 YVKVKISGRMAVVSEECSTKLKFQGNEIEVAGEASVQEIQKQTYTTPAGKEVKVYQADFV 316
Query: 257 DPNFGTGAVYNCTYGDEQDIVWQKR---YNLPVII----------------------AIN 291
DP+ GTG VY+ D V+ ++ + PVII
Sbjct: 317 DPDNGTGIVYSVPSHSVYDYVYYRKKRGKDFPVIIEAPMKMKDIESKYDLETEEGREEAT 376
Query: 292 EDGTMNE-------NAGPYAGLKVEEARKKIAEDLEKMGLLYK-KEKIKHRVLRHTERSS 343
+D NE ++GPY G+ V EAR+ + DL G + E +H V RS
Sbjct: 377 KDLYRNEFYYGKLVDSGPYTGMTVREAREAVKRDLISSGNAFTFYETSRHAV----TRSG 432
Query: 344 CMAPIELLPKKQWFIRVKDFTDEIVK-----VAKEINWYPEDMFLRLKDWAESMDW--DW 396
+ +LP QWF+ D++ +K + + +PE + D ++DW +
Sbjct: 433 SKVIVAVLP-DQWFL---DYSQPWLKDLGHTMINTMTMHPEVYRNVMND---AIDWLKER 485
Query: 397 VISRQRVFGTPFPF---WVCK---NGHIIPA-REEDLPVDPRFDKPPVEKCPVCGAEIEP 449
+R+R GT PF WV + + I PA +P+ ++
Sbjct: 486 PCARRRGLGTRLPFDDRWVIESLSDSTIYPAVYTNSIPLRSLYE---------------- 529
Query: 450 VTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIF 509
T LD D +IT I + + EAK+ FE+ +P +R I + +
Sbjct: 530 -TGKLD---DDAIT-RIFMNGEPKNEDESEAKRQFEYWYPVDIRLTAIPHISNHLSFYVL 584
Query: 510 RTFKLTGKKPW-KDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPP 568
+ K+ W ++I+G+V +G K+SKS GNVV+ E+ KY AD RL+ A+
Sbjct: 585 NHAAIFPKEKWPAGLIISGLVVS-NGAKISKSKGNVVSLLEIAKKYSADIYRLYVAVQAD 643
Query: 569 GEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIELEPLDRWILSRLHRII 628
T+D+N L + + + + F + D+ E + W ++R +
Sbjct: 644 IS------STMDWNETDLASITRRFNEFKDLMAGFKQDT-SDLTFE--EAWFVARFSVRL 694
Query: 629 KFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYN 688
+ E ++RY+ R+ I++ V +D ++Y + ++ AL ++ +
Sbjct: 695 RQFMESMDRYQI----RDAYINIFYGVLND----LRYLSSRGGDVNR-----ALTPVIAD 741
Query: 689 VMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSE 748
+ L P +PH EE +H+ D V + + E +DR + + G ++ S
Sbjct: 742 WLRALMPVIPHHAEEYWHSYVSDTY----VSVDPFDENFQDRYERTVRRFGMTCDQMYSA 797
Query: 749 M 749
M
Sbjct: 798 M 798
>sp|Q9ZJ63|SYL_HELPJ LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437531|pir||G71805 leucine--tRNA ligase (EC
6.1.1.4) - Helicobacter pylori (strain J99)
>gi|4156066|gb|AAD07021.1| (AE001567) LEUCYL-TRNA
SYNTHETASE [Helicobacter pylori J99]
Length = 806
Score = 168 bits (420), Expect = 3e-40
Identities = 202/898 (22%), Positives = 352/898 (38%), Gaps = 232/898 (25%)
Query: 11 IEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKRMR 70
IE KWQ++W + K ++ + D N P I + P+ SG +H+GHV ++T D +ARY R+
Sbjct: 6 IEKKWQEFWWKNKSFEPKDDFNLPKKYILSMLPYPSGEIHMGHVRNYTIGDALARYYRLH 65
Query: 71 GYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMRKQFIRIGYS 130
YNVL P GFD+ G+P E K GI P+ WT++ IEAM+K+F +G+S
Sbjct: 66 HYNVLHPMGFDSFGMPAENAAIKH-GI---HPKT-------WTYENIEAMQKEFEALGFS 114
Query: 131 ADWDLEYHT-------------MDDWYKAAV--QKSLLEFYK--KGLIYREEHPVYWCPK 173
+ E+ T +D W K + +K++L + K ++ E+ C +
Sbjct: 115 FSKNREFATSDPDYTKFEQQFFIDLWEKGLIYRKKAMLNWCPNDKTVLANEQVIDGRCWR 174
Query: 174 CRTSLAKAEV--------GYVEE---------------------------EGYLYYIK-- 196
C T + + E+ Y EE G + K
Sbjct: 175 CDTEVIQKELYQYYLKITNYAEELLKDLETLENHWPSQVLTMQKNWIGKSSGLQFGFKIA 234
Query: 197 ---LPLADGSGYIPIATTRPELMPACVAVFVHPDDERYKHLV-------GKKVKL----- 241
L + I + TTR + + + + P+ +H + K +K
Sbjct: 235 DECLKACNNIQEIEVFTTRADTIYGVTYIAIAPEHPLVEHAIKRVSQEDSKMIKAILNTT 294
Query: 242 -------------------PIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRY 282
P+ ++++P+ N+G+GA+ DE+D + Y
Sbjct: 295 QRERALEKKGAFLGIYAIHPLTKQKIPVWVANFALANYGSGALMGVPACDERDFEFANLY 354
Query: 283 NLPVIIAINEDGTMN-------ENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRV 335
++P+ + + +N+G ++ L AR+KI ++KE + RV
Sbjct: 355 HIPIKVITQSPQNLPHTKEEILKNSGEWSDLSSSVAREKIIA-------YFEKENLGKRV 407
Query: 336 LRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWD 395
+ + RL+DW
Sbjct: 408 INY---------------------------------------------RLQDWG------ 416
Query: 396 WVISRQRVFGTPFPFWVCKNGHIIPARE------EDLPVDPRFDKPPVEK--------CP 441
+SRQR +G P P CK+ I+P + ED+ +D + P+EK CP
Sbjct: 417 --VSRQRYWGAPIPMIHCKHCGIVPETQLPVTLPEDIVIDGEGN--PLEKHASWKFAQCP 472
Query: 442 VCGAEIEPVTDVLDCWVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIR 501
C + TD +D ++ SS L T + + + ++ P G +
Sbjct: 473 KCHKDALRETDTMDTFIQSSWYFLRYTTPKNQRENQAFDQNYLKYFMPVDTYIGGIEHAI 532
Query: 502 TWAFYTIFRTFKLTG------KKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYG 555
Y F T L +P+K ++ GMV DG KMSKS GNVV+P E++ KYG
Sbjct: 533 LHLLYARFFTKALRDLGYLHLDEPFKQLITQGMVL-KDGAKMSKSKGNVVSPKEILKKYG 591
Query: 556 ADALRLWTAL-APPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIELE 614
ADA+RL+ APP ++ + ++ RF+++ +Y A ++K++ L
Sbjct: 592 ADAVRLFILFAAPPAKELEWNDNALEGAHRFIKR---LYDKANAITPTTSKPEFKEVGLN 648
Query: 615 PLDRWILSRLHRIIKFATEELER----YRFNLITRELMTFIWHEVADDYIEMVKYRLYGD 670
+ +++ +K + E + Y FN + M E +
Sbjct: 649 EAQKLARKKVYEALKKSHEIFNKAESAYAFNTLIASCM------------EALNALNAQS 696
Query: 671 DEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYREDR 730
DE+ L E + ++ +L P +PH E+ +FK + ++
Sbjct: 697 DEQ-------ILCEGYFVLLQILEPMIPHTAWELSERLFKRE------------NFKPIE 737
Query: 731 IDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYA---LESYDDLKLIEKDI 785
+DE A + + ++ K + + +NA E + I A LE Y + ++K+I
Sbjct: 738 VDESA-LIEDFMTLGLTINGKRRAELKVNINASKEEIIILAKKELEKYLENASVKKEI 794
>dbj|BAA28840.1| (AB008526) Valyl tRNA Synthetase [Trichomonas vaginalis]
Length = 455
Score = 166 bits (417), Expect = 8e-40
Identities = 117/399 (29%), Positives = 190/399 (47%), Gaps = 35/399 (8%)
Query: 5 KYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIA 64
+Y+P ++E W +W + ++ + + K + + PPP +G LHLGH L+ + D I
Sbjct: 52 EYNPMKVENAWYSWWENQNFFEPKAADKK--FVMILPPPNVTGELHLGHALTASIEDAIT 109
Query: 65 RYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKD------QPEEFLKKCVEWTWQAIE 118
RY RM G L+ G D+ G+ T+ +VEK+ K E FL++ +W
Sbjct: 110 RYHRMCGEESLWVPGTDHAGIATQFRVEKKIYDEKKLHRGEYSREYFLEEAHKWVESKSG 169
Query: 119 AMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSL 178
+ Q +G S W Y+T+D+ +V + ++ + +GLIYR E V W +T++
Sbjct: 170 TILSQLRDMGSSLAWKDTYYTLDEKRSESVIAAFIKLFDEGLIYRSERLVNWDCALKTAI 229
Query: 179 AKAEVGYVE-----------------EEGYLYYIKLPLADGSG-----YIPIATTRPELM 216
+ AEV Y+ G + + + D G + IATTR E M
Sbjct: 230 SDAEVEYITLTKRTKLNVPNHKYPQYPFGVMTHFYYEICDKDGKKTGEKVEIATTRLETM 289
Query: 217 PACVAVFVHPDDERYKHLVGKKVKLPIYEREVPILADED-VDPNFGTGAVYNCTYGDEQD 275
AV ++P D RY HL G V PI E +PI+ DE VD NFGTG V D D
Sbjct: 290 LGDTAVAINPKDARYNHLHGMYVWHPIREVPIPIIQDEILVDMNFGTGVVKVTPGHDPND 349
Query: 276 I-VWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHR 334
V+++ + +I + DG + G ++G+ +AR ++ + +++ G LYK+EK
Sbjct: 350 YEVYKRHPEIGLISILTPDGAIASGYGQFSGMMRFDARVEMVKWMKEHG-LYKEEKDHEM 408
Query: 335 VLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKE 373
L T+R + +E + QWF+ D +K +
Sbjct: 409 RLGITQRGHDI--VEQVITPQWFVNTTDMAARAIKAVDD 445
>dbj|BAA28841.1| (AB008527) Valyl tRNA Synthetase [Trichomonas vaginalis]
Length = 455
Score = 166 bits (416), Expect = 1e-39
Identities = 117/399 (29%), Positives = 190/399 (47%), Gaps = 35/399 (8%)
Query: 5 KYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIA 64
+Y+P ++E W +W + ++ + + K + + PPP +G LHLGH L+ + D I
Sbjct: 52 EYNPMKVENAWYSWWENQNFFEPKAADKK--FVMILPPPNVTGELHLGHALTASIEDAIT 109
Query: 65 RYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKD------QPEEFLKKCVEWTWQAIE 118
RY RM G L+ G D+ G+ T+ +VEK+ K E FL++ +W
Sbjct: 110 RYHRMCGEESLWVPGTDHAGIATQFRVEKKIYDEKKLHRGEYSREYFLEEAHKWVESKSG 169
Query: 119 AMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSL 178
+ Q +G S W Y+T+D+ +V + ++ + +GLIYR E V W +T++
Sbjct: 170 TILSQLRDMGSSLAWKDTYYTLDEKRSESVIAAFIKLFDEGLIYRSERLVNWDCALKTAI 229
Query: 179 AKAEVGYVE-----------------EEGYLYYIKLPLADGSG-----YIPIATTRPELM 216
+ AEV Y+ G + + + D G + IATTR E M
Sbjct: 230 SDAEVEYITLTKRTKLNVPNHKYPQYPFGVMTHFYYEICDKDGKKTGEKVEIATTRLETM 289
Query: 217 PACVAVFVHPDDERYKHLVGKKVKLPIYEREVPILADED-VDPNFGTGAVYNCTYGDEQD 275
AV ++P D RY HL G V PI E +PI+ DE VD NFGTG V D D
Sbjct: 290 LGDTAVAINPKDARYNHLHGMYVWHPIREVPIPIIQDEILVDMNFGTGVVKVTPGHDPND 349
Query: 276 I-VWQKRYNLPVIIAINEDGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHR 334
V+++ + +I + DG + G ++G+ +AR ++ + +++ G LYK+EK
Sbjct: 350 YEVYKRHPEIGLISILTPDGAIAPGYGQFSGMMRFDARVEMVKWMKEHG-LYKEEKDHEM 408
Query: 335 VLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKE 373
L T+R + +E + QWF+ D +K +
Sbjct: 409 RLGITQRGHDI--VEQVITPQWFVNTTDMAARAIKAVDD 445
>gb|AAK40823.1| Leucyl-tRNA synthetase (leuS-1) [Sulfolobus solfataricus]
Length = 934
Score = 165 bits (413), Expect = 2e-39
Identities = 221/923 (23%), Positives = 386/923 (40%), Gaps = 145/923 (15%)
Query: 9 NEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKR 68
N I KWQ W + K+++ +D +KP + I P P+T+ +H+GH ++ DI ARY R
Sbjct: 7 NSIAFKWQAEWEKSKVFETNMDYSKPKFFITVPFPYTNSPMHVGHGRTYITADIYARYLR 66
Query: 69 MRGYNVLFPQGFDNHGLPT----------ELKVEKEFGITKDQPEEFLKKCVEWTWQAIE 118
M+GYNVLFP F G P E+ V + F + P++ +K+ +E ++ E
Sbjct: 67 MKGYNVLFPFAFQFTGTPVLAIADSIRRGEVDVIEFFKNVYEVPQDKIKE-LEDPYKLAE 125
Query: 119 AMRKQFIR----IGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKC 174
+++ IG S DW + T D ++ + L + + G + E+ V +CP
Sbjct: 126 YFKEEMKNTAKSIGMSIDWRRTFTTTDPRFEKFIHWQLGKLKELGYLVTEDDVVGYCPND 185
Query: 175 RTSLAKAEV-GYVEEEGYLYYIKLPLADGSGYIPIATTRPELMPACVAVFVHPD------ 227
+ + G +E E + + S +AT+RPEL+ VA+ V+ D
Sbjct: 186 GFPVGMHDTRGDIEPEITTMNVIMFEGSDSYNFMVATSRPELIFGVVALMVNHDANYVVV 245
Query: 228 ----------DERYKHLVGKK-------------VKL----PIYEREVPILADEDVDPNF 260
++ YK L +K VKL PI R++ I+ ++ VDP+
Sbjct: 246 EYEGKNFIISEKAYKKLSFQKNMKLVKTITTSDIVKLYAINPITGRKLEIIKNKYVDPSL 305
Query: 261 GTGAVYNCTYGDEQDIVWQKRYNLPV-IIAINEDGTMNENAGPYAGLKVEE--ARKKIAE 317
GTG V + D + N +I + E ++E G A L+ + A K E
Sbjct: 306 GTGVVMSYPAHDPFHYLAMTETNKEFEVIPVVETEELDEIPGESAVLQTKNPYALKDFME 365
Query: 318 DLEK------------MGLL--YKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDF 363
+ K + L+ + K+ +K ++ + + IELL + + D
Sbjct: 366 SIYKTEYYKGYMKDIILSLVPDFLKQYVKENIVGKQVQEARKNTIELLKS----LNIYDT 421
Query: 364 TDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHII--PA 421
EI E + R+KD W I+ N +I P
Sbjct: 422 IYEISNGPIYCRCGSEIVPKRIKD-------QWFIAYDNPKWKASALKAINNIELIPNPT 474
Query: 422 REEDLPVDPRFDKPPVEKCPVCGAEIE-PVTDVLDCWVDSSITPLIITRWHEAI------ 474
+ E + K P+ + G ++ + +++ DS++ L+ T ++
Sbjct: 475 KTELEKIVFNARKEPIGRSRGIGVKLPWDESQIVESLSDSTLYTLLYTVIYKMPINIEKE 534
Query: 475 --------KGDE------------EAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKL 514
KGD + ++ F + +P R G D+I+ + I+ +
Sbjct: 535 IFDFIFLGKGDAKELERKYGTDLIQLREEFLYWYPVDQRHTGRDLIQNHIPFYIYNHLAI 594
Query: 515 TGKKPW-KDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRL-WTALAPPGEDH 572
G+K K IVING V GRKMSKS N+ + I ++G D +R+ T+ + +D
Sbjct: 595 FGEKYLPKRIVINGFVR-VGGRKMSKSLRNIYTLSKAIKEFGVDPVRIALTSTSDLLQDL 653
Query: 573 PFKWETVDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIELEPLDRWILSRLHRIIKFAT 632
F V+ L+K IY +R + K EL D WI S++ II+
Sbjct: 654 DFNENLVNPIAEQLKK---IYDLIDRLLSINTEIK----ELRTADEWISSKVRDIIEKVN 706
Query: 633 EELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLL 692
+ +++ L+ + +E+ DY ++V ++ + + ++L +
Sbjct: 707 NNITSFKYRDAV-NLLLYEIYEILRDYFDLV-----------EIPNQEVIRKILSIWIRA 754
Query: 693 LAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKY 752
LAPFVPHI EE++H KI V L +PE E + A K++ +R+
Sbjct: 755 LAPFVPHIAEELWH-----KISSTFVSLEKYPEPNELNLYPDAILEISYINKIIENVREL 809
Query: 753 KNSHGMPLNAKLEHVAIYALESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLEERIVEVKP 812
++ ++ K E V IY ES + +K + K+ +N E++ + + E++I E
Sbjct: 810 EDI----VHKKAEKVIIYINES-EKVKELMKNAIKAVN-EEIPLREFTANTEDKIAE--- 860
Query: 813 NYKRIGPRYGKLVPRIVEHLKNN 835
++ KL I ++L NN
Sbjct: 861 ---KVYVVVSKLDKAIRDYLLNN 880
>sp|P43827|SYL_HAEIN LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|1074962|pir||H64102 leucine--tRNA ligase (EC
6.1.1.4) - Haemophilus influenzae (strain Rd KW20)
>gi|1573943|gb|AAC22581.1| (U32774) leucyl-tRNA
synthetase (leuS) [Haemophilus influenzae Rd]
Length = 861
Score = 134 bits (334), Expect = 4e-30
Identities = 74/182 (40%), Positives = 101/182 (54%), Gaps = 11/182 (6%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+ ++Y P+ IEPK Q+YW E K++K DE+K Y + P+ SG LH+GHV ++T D
Sbjct: 1 MQEQYRPDMIEPKVQQYWAENKVFKAIKDESKEKYYCLSMFPYPSGRLHMGHVRNYTIGD 60
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMR 121
+I+RY+RM G NVL P G+D GLP E K K P +WT++ I M+
Sbjct: 61 VISRYQRMLGKNVLQPFGWDAFGLPAEGAAIK----NKTAP-------AKWTYENIAYMK 109
Query: 122 KQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKA 181
KQ +G+ DWD E T Y Q E YKKGL+Y++ V WCP T LA
Sbjct: 110 KQLQLLGFGFDWDREIATCKPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANE 169
Query: 182 EV 183
+V
Sbjct: 170 QV 171
>dbj|BAB14164.1| (AK022665) unnamed protein product [Homo sapiens]
Length = 567
Score = 131 bits (326), Expect = 4e-29
Identities = 114/417 (27%), Positives = 180/417 (42%), Gaps = 59/417 (14%)
Query: 325 LYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVKDFTDEIVKVAKEINWYPEDMFLR 384
L K+EK+ H P+ + KQWFI + D ++ K++ + P
Sbjct: 8 LLKEEKLVHSYPYDWRTKK---PVVIRASKQWFINITDIKTAAKELLKKVKFIPGSA--- 61
Query: 385 LKDWAESMDWD--WVISRQRVFGTPFPFWVCKNG-----------HIIPAREEDLPVDPR 431
L E MD W ISRQRV+G P P + K HI+ E+ D
Sbjct: 62 LNGMVEMMDRRPYWCISRQRVWGVPIPVFHHKTKDEYLINSQTTEHIVKLVEQH-GSDIW 120
Query: 432 FDKPPVEKCP------VCGA---EIEPVTDVLDCWVDSSITPLIITRWHEAIKG-DEEAK 481
+ PP + P V G E P D+LD W DS T W + G D+ A
Sbjct: 121 WTLPPEQLLPKEVLSEVGGPDALEYVPGQDILDIWFDSG------TSWSYVLPGPDQRAD 174
Query: 482 KWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSY 541
+ E G D + W ++ + + +K ++++G G G KMSKS
Sbjct: 175 LYLE----------GKDQLGGWFQSSLLTSVAARKRALYKTVIVHGFTLGEKGEKMSKSL 224
Query: 542 GNVVAPDEVI---------PKYGADALRLWTALAPPGEDHPFKWETVDYNFRFLQKVWNI 592
GNV+ PD V+ P YGAD LR W A + + ++ + K+ N
Sbjct: 225 GNVIHPDVVVNGGQDQSKEPPYGADVLRWWVADSNVFTEVAIGPSVLNAARDDISKLRNT 284
Query: 593 YRFAERHIKDFDYE--KYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTF 650
RF ++ DF+ E ++ +D+++L L + TE ++Y F + R L TF
Sbjct: 285 LRFLLGNVADFNPETDSIPVNDMYVIDQYMLHLLQDLANKITELYKQYDFGKVVRLLRTF 344
Query: 651 IWHEVADDYIEMVKYRLYGDDEE--SKLKAKVALYELLYNVMLLLAPFVPHITEEIY 705
E+++ Y ++K RLY + E + + AL E+L ++ AP +PH+ EE++
Sbjct: 345 YTRELSNFYFSIIKDRLYCEKENDPKRRSCQTALVEILDVIVRSFAPILPHLAEEVF 401
>sp|Q9ZDB1|SYL_RICPR LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437545|pir||D71700 leucine--tRNA ligase (EC
6.1.1.4) (leuS) RP421 - Rickettsia prowazekii
>gi|3860978|emb|CAA14878.1| (AJ235271) LEUCYL-TRNA
SYNTHETASE (leuS) [Rickettsia prowazekii]
Length = 828
Score = 128 bits (318), Expect = 3e-28
Identities = 72/201 (35%), Positives = 108/201 (52%), Gaps = 19/201 (9%)
Query: 9 NEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKR 68
++IE KWQK W EEK ++ + +KP Y + P+ SG +H+GHV +++ D+IAR+
Sbjct: 2 HKIEKKWQKIWQEEKAFQVSNESSKPKYYVLEMLPYPSGKIHIGHVRNYSIGDVIARFMT 61
Query: 69 MRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMRKQFIRIG 128
M+G+NVL P G+D GLP E K +P+ +WT+ IE M+KQ +G
Sbjct: 62 MQGFNVLHPMGWDAFGLPAENAAIK----NNSRPQ-------DWTYSNIEYMKKQLQSMG 110
Query: 129 YSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV----- 183
++ DW E ++ D Y QK LE Y + L+Y++E V W P T LA +V
Sbjct: 111 FAYDWTREINSCDPEYYKHEQKFFLELYDRNLVYQKESLVNWDPVDNTVLANEQVVDGRG 170
Query: 184 ---GYVEEEGYLYYIKLPLAD 201
G + E+ YL L + D
Sbjct: 171 WRSGAIIEKRYLKQWFLKITD 191
>pir||G81698 leucyl-tRNA synthetase TC0481 [imported] - Chlamydia muridarum
(strain Nigg) >gi|7190521|gb|AAF39327.1| (AE002316)
leucyl-tRNA synthetase [Chlamydia muridarum]
Length = 819
Score = 127 bits (315), Expect = 7e-28
Identities = 74/191 (38%), Positives = 106/191 (54%), Gaps = 16/191 (8%)
Query: 5 KYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGT-LHLGHVLSHTWIDII 63
+YDP+ IE KWQK+W EE+ ++ DE K Y + P+ SG LH+GH++ +T DI+
Sbjct: 2 RYDPSLIEEKWQKFWKEEQTFRAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIV 61
Query: 64 ARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGI-TKDQPEEFLKKCVEWTWQAIEAMRK 122
ARYKR +G++VL P G+D+ GLP E ++ I T P E +K I ++
Sbjct: 62 ARYKRAKGFSVLHPMGWDSFGLPAE-----QYAIRTGTHPRETTEK-------NIANFKQ 109
Query: 123 QFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAE 182
Q +G+S D E+ T D Y QK L Y+KGL Y + V +CP+ T L+ E
Sbjct: 110 QLTSMGFSYDESREFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEE 169
Query: 183 V--GYVEEEGY 191
V G+ E GY
Sbjct: 170 VENGFSVEGGY 180
>pir||A41882 leucine--tRNA ligase (EC 6.1.1.4) - Bacillus subtilis
>gi|143148|gb|AAA22571.1| (M88581) transfer RNA-Leu
synthetase [Bacillus subtilis]
Length = 804
Score = 126 bits (314), Expect = 9e-28
Identities = 75/181 (41%), Positives = 99/181 (54%), Gaps = 16/181 (8%)
Query: 6 YDPNEIEPKWQKYWLEEKIYKYRLDENKPS--YAIDTPPPFTSGTLHLGHVLSHTWIDII 63
+ EIE KWQ YWLE K + LD N+ YA+D P + LH+GH +T DI+
Sbjct: 3 FQHKEIEKKWQTYWLENKTFA-TLDNNEKQKFYALDMFPYPSGAGLHVGHPEGYTATDIL 61
Query: 64 ARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGI-TKDQPEEFLKKCVEWTWQAIEAMRK 122
+R KRM+GY+VL P G+D GLP E ++ + T + P F K Q I+ R+
Sbjct: 62 SRMKRMQGYDVLHPMGWDAFGLPAE-----QYALDTGNDPAVFTK-------QNIDNFRR 109
Query: 123 QFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAE 182
Q +G+S DWD E +T D Y Q L+ Y+KGL Y +E PV WCP T LA E
Sbjct: 110 QIQALGFSYDWDREINTTDPEYYKWTQWIFLKLYEKGLAYVDEVPVNWCPALGTVLANEE 169
Query: 183 V 183
V
Sbjct: 170 V 170
Score = 100 bits (246), Expect = 9e-20
Identities = 133/541 (24%), Positives = 219/541 (39%), Gaps = 125/541 (23%)
Query: 242 PIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAG 301
P+ ++PI + V ++GTGAV DE+D + K + LPV + + G + E A
Sbjct: 312 PVNGEKLPIWIADYVLASYGTGAVMAVPGHDERDFEFAKTFGLPVKEVV-KGGNVEEAAY 370
Query: 302 PYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVK 361
G V + + L+K+E I+ +V
Sbjct: 371 TGDGEHVNS---------DFLNGLHKQEAIE--------------------------KVI 395
Query: 362 DFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPA 421
+ +E K++ + RL+DW + SRQR +G P P ++G
Sbjct: 396 AWLEETKNGEKKVTY-------RLRDW--------LFSRQRYWGEPIPVIHWEDGTSTAV 440
Query: 422 REEDLP-VDPRFD--KP------PVEKC--------PVCGAEIEPVTDVLDCWVDSSITP 464
EE+LP + P+ D KP P+ P G + T+ + W S
Sbjct: 441 PEEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGKKGRRETNTMPQWAGSCWYF 500
Query: 465 LIITRWH--EAIKGDEEAKKWFEHNFPTALRPQGTD-------IIRTWAFYTIFRTFKLT 515
L H + + E+ +KW P + G + R W + ++ +
Sbjct: 501 LRYIDPHNPDQLASPEKLEKWL----PVDMYIGGAEHAVLHLLYARFWHKF-LYDIGVVP 555
Query: 516 GKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFK 575
K+P++ + GM+ G + KMSKS GNVV PDE++ +GAD LRL+ P D
Sbjct: 556 TKEPFQKLYNQGMILGENNEKMSKSKGNVVNPDEIVASHGADTLRLYEMFMGP-LDASIA 614
Query: 576 WET--VDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIE--LEPLDRWILSRLHRIIKFA 631
W +D RFL +VW ++ I+D K +E E L+R H +
Sbjct: 615 WSESGLDGARRFLDRVWRLF------IEDSGELNGKIVEGAGETLER----VYHETVMKV 664
Query: 632 TEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVML 691
T+ E RFN +LM FI KA E + +
Sbjct: 665 TDHYEGLRFNTGISQLMVFI---------------------NEAYKATELPKEYMEGFVK 703
Query: 692 LLAPFVPHITEEIYHAMFKDKIGEK-SVHLLSWPEYREDR-IDEKAEKLGELARKVVSEM 749
LL+P PH+ EE++ +K+G ++ +WP Y E + +D++ E + +L KV +++
Sbjct: 704 LLSPVAPHLAEELW-----EKLGHSGTIAYEAWPVYDETKLVDDEVEIVVQLNGKVKAKL 758
Query: 750 R 750
+
Sbjct: 759 Q 759
>sp|P36430|SYL_BACSU LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437539|pir||D69650 leucine--tRNA ligase (EC
6.1.1.4) - Bacillus subtilis >gi|2293181|gb|AAC00259.1|
(AF008220) leucine tRNA synthetase [Bacillus subtilis]
>gi|2635516|emb|CAB15010.1| (Z99119) leucyl-tRNA
synthetase [Bacillus subtilis]
Length = 804
Score = 126 bits (314), Expect = 9e-28
Identities = 75/181 (41%), Positives = 99/181 (54%), Gaps = 16/181 (8%)
Query: 6 YDPNEIEPKWQKYWLEEKIYKYRLDENKPS--YAIDTPPPFTSGTLHLGHVLSHTWIDII 63
+ EIE KWQ YWLE K + LD N+ YA+D P + LH+GH +T DI+
Sbjct: 3 FQHKEIEKKWQTYWLENKTFA-TLDNNEKQKFYALDMFPYPSGAGLHVGHPEGYTATDIL 61
Query: 64 ARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGI-TKDQPEEFLKKCVEWTWQAIEAMRK 122
+R KRM+GY+VL P G+D GLP E ++ + T + P F K Q I+ R+
Sbjct: 62 SRMKRMQGYDVLHPMGWDAFGLPAE-----QYALDTGNDPAVFTK-------QNIDNFRR 109
Query: 123 QFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAE 182
Q +G+S DWD E +T D Y Q L+ Y+KGL Y +E PV WCP T LA E
Sbjct: 110 QIQALGFSYDWDREINTTDPEYYKWTQWIFLKLYEKGLAYVDEVPVNWCPALGTVLANEE 169
Query: 183 V 183
V
Sbjct: 170 V 170
Score = 100 bits (246), Expect = 9e-20
Identities = 133/541 (24%), Positives = 219/541 (39%), Gaps = 125/541 (23%)
Query: 242 PIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGTMNENAG 301
P+ ++PI + V ++GTGAV DE+D + K + LPV + + G + E A
Sbjct: 312 PVNGEKLPIWIADYVLASYGTGAVMAVPGHDERDFEFAKTFGLPVKEVV-KGGNVEEAAY 370
Query: 302 PYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFIRVK 361
G V + + L+K+E I+ +V
Sbjct: 371 TGDGEHVNS---------DFLNGLHKQEAIE--------------------------KVI 395
Query: 362 DFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKNGHIIPA 421
+ +E K++ + RL+DW + SRQR +G P P ++G
Sbjct: 396 AWLEETKNGEKKVTY-------RLRDW--------LFSRQRYWGEPIPVIHWEDGTSTAV 440
Query: 422 REEDLP-VDPRFD--KP------PVEKC--------PVCGAEIEPVTDVLDCWVDSSITP 464
EE+LP + P+ D KP P+ P G + T+ + W S
Sbjct: 441 PEEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETGKKGRRETNTMPQWAGSCWYF 500
Query: 465 LIITRWH--EAIKGDEEAKKWFEHNFPTALRPQGTD-------IIRTWAFYTIFRTFKLT 515
L H + + E+ +KW P + G + R W + ++ +
Sbjct: 501 LRYIDPHNPDQLASPEKLEKWL----PVDMYIGGAEHAVLHLLYARFWHKF-LYDIGVVP 555
Query: 516 GKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFK 575
K+P++ + GM+ G + KMSKS GNVV PDE++ +GAD LRL+ P D
Sbjct: 556 TKEPFQKLYNQGMILGENNEKMSKSKGNVVNPDEIVASHGADTLRLYEMFMGP-LDASIA 614
Query: 576 WET--VDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIE--LEPLDRWILSRLHRIIKFA 631
W +D RFL +VW ++ I+D K +E E L+R H +
Sbjct: 615 WSESGLDGARRFLDRVWRLF------IEDSGELNGKIVEGAGETLER----VYHETVMKV 664
Query: 632 TEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVML 691
T+ E RFN +LM FI KA E + +
Sbjct: 665 TDHYEGLRFNTGISQLMVFI---------------------NEAYKATELPKEYMEGFVK 703
Query: 692 LLAPFVPHITEEIYHAMFKDKIGEK-SVHLLSWPEYREDR-IDEKAEKLGELARKVVSEM 749
LL+P PH+ EE++ +K+G ++ +WP Y E + +D++ E + +L KV +++
Sbjct: 704 LLSPVAPHLAEELW-----EKLGHSGTIAYEAWPVYDETKLVDDEVEIVVQLNGKVKAKL 758
Query: 750 R 750
+
Sbjct: 759 Q 759
>sp|O84211|SYL_CHLTR LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437540|pir||C71544 leucine--tRNA ligase (EC
6.1.1.4) - Chlamydia trachomatis (serotype D, strain
UW3/Cx) >gi|3328616|gb|AAC67801.1| (AE001294) Leucyl
tRNA Synthetase [Chlamydia trachomatis]
Length = 819
Score = 126 bits (314), Expect = 9e-28
Identities = 73/191 (38%), Positives = 105/191 (54%), Gaps = 16/191 (8%)
Query: 5 KYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGT-LHLGHVLSHTWIDII 63
+YDP IE KWQK+W E+++K DE K Y + P+ SG LH+GH++ +T DI+
Sbjct: 2 RYDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIV 61
Query: 64 ARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGI-TKDQPEEFLKKCVEWTWQAIEAMRK 122
ARYKR +G++VL P G+D+ GLP E ++ I T P E +K I +K
Sbjct: 62 ARYKRAQGFSVLHPMGWDSFGLPAE-----QYAIRTGTHPRETTEK-------NIANFKK 109
Query: 123 QFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAE 182
Q +G+S D E+ T D Y QK L Y+KGL Y + V +CP+ T L+ E
Sbjct: 110 QLTAMGFSYDESREFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEE 169
Query: 183 V--GYVEEEGY 191
+ G+ + GY
Sbjct: 170 IENGFSVDGGY 180
>emb|CAA83769.1| (Z33122) Val-tRNA synthetase [Mycoplasma capricolum]
Length = 260
Score = 126 bits (313), Expect = 1e-27
Identities = 76/223 (34%), Positives = 125/223 (55%), Gaps = 9/223 (4%)
Query: 496 GTDIIRTWAFYTIFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYG 555
G DII W F F++ K P+KD++I+G+V RKMSKS GN + P +VI G
Sbjct: 22 GYDIIFFWVAGNDFSNFRIY-KIPFKDVLIHGLVRDELNRKMSKSLGNGIDPMDVINNNG 80
Query: 556 ADALRLWTAL-APPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKD---FDYEKYKDI 611
D+LRL+ + PG+D + E + ++ F+ K+WN R+ ++ D FD YK
Sbjct: 81 CDSLRLFLLTNSTPGQDIRYSNEKILASWNFINKLWNASRYVFLNLDDHFEFDPNFYK-T 139
Query: 612 ELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDD 671
+LE ++WIL++L + + E++ +Y F+L L F+W++ YIE K L D
Sbjct: 140 DLEITNQWILTQLSKTQAYVYEKMNKYEFSLAGNHLWDFVWNKYCSWYIEFSKVNLSND- 198
Query: 672 EESKLKAKVALYELLYNVMLLLAPFVPHITEEIY-HAMFKDKI 713
+ + K L+ +L ++++L P +P ++EEIY + M K+ I
Sbjct: 199 -KFNYQTKQTLFYVLKEILIMLHPLIPFVSEEIYLNMMLKESI 240
>pir||H75133 leucyl-tRNA synthetase (leus) PAB1782 - Pyrococcus abyssi (strain
Orsay) >gi|5458296|emb|CAB49785.1| (AJ248285)
leucyl-tRNA synthetase (leuS) [Pyrococcus abyssi]
Length = 967
Score = 125 bits (311), Expect = 2e-27
Identities = 109/389 (28%), Positives = 177/389 (45%), Gaps = 72/389 (18%)
Query: 11 IEPKWQKYWLEEKIYKYRLDEN--KPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIARYKR 68
IE KWQK WLE K+++ + + + + I P+ SG LH+GH ++T D+IAR+KR
Sbjct: 9 IEEKWQKRWLEAKVFEPNIKDKPKEKKFYITVAFPYLSGHLHVGHARTYTIPDVIARFKR 68
Query: 69 MRGYNVLFPQGFDNHGLPTELKVEK-------EFGITKD---QPEEFLKKCVEWTWQ--- 115
M+GYNVLFP G+ G P E+ I +D PEE L WT++
Sbjct: 69 MQGYNVLFPMGWHITGSPIVGIAERIKNRDPHTIWIYRDVYKVPEEIL-----WTFEDPV 123
Query: 116 -----AIEAMRKQFIRIGYSADWDLEYHTMDDW--YKAAVQKSLLEFYKKGLIYREEHPV 168
++A ++ FIR G+S DW E++T + + ++ L+ +KG I + H V
Sbjct: 124 NIVKYFMKAAKETFIRAGFSVDWSREFYTTSLFPPFSKFIEWQFLKLKEKGYIVKGAHRV 183
Query: 169 YWCPKCRTSLAKAEVGYVEEEGYLYY--IKLPLADGSG--YIPIATTRPELMPACVAVFV 224
W P T L ++ E+ L Y IK L +G Y+P AT RPE + +++
Sbjct: 184 RWDPVVGTPLGDHDLMEGEDVPILEYVIIKFELKEGDETIYLPAATLRPETVYGVTNMWI 243
Query: 225 HPD---------------------DERYK-----------------HLVGKKVKLPIYER 246
+P+ + YK L+GK V+ P+
Sbjct: 244 NPNATYVKAKVKRGGKEETWIISKEAAYKLSFQDREIEVIEEFKGEKLIGKYVRNPVTGD 303
Query: 247 EVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQK--RYNLPVIIAINEDGTMNENAGPYA 304
EV IL E VDP+ TG V + D V + + +++ + D + E +
Sbjct: 304 EVIILPAEFVDPDNATGVVMSVPAHAPFDHVALEDLKRESEILVKYDIDPRIVEEITYIS 363
Query: 305 GLKVE-EARKKIAEDLEKMGLLYKKEKIK 332
+K+E E+++K+G+ +K++ K
Sbjct: 364 LIKLEGYGEFPAVEEVQKLGIKSQKDREK 392
Score = 113 bits (281), Expect = 7e-24
Identities = 128/478 (26%), Positives = 223/478 (45%), Gaps = 71/478 (14%)
Query: 302 PYAGLKVEEARKKIAEDLEKMGL---LYKKEKIKHRVLRHTERSSCMAPIELLPKKQWFI 358
PY G V+E ++ IA+++ + G+ +Y+ + K+ + R R A I+++ QWFI
Sbjct: 414 PYDGKPVQEVKELIAKEMMEKGIAEIMYEFAE-KNVISRFGNR----AVIKII-HDQWFI 467
Query: 359 RV--KDFTDEIVKVAKEINWYPED---MFLRLKDWAESMDWDWVISRQRVFGTPFPF--- 410
++ ++ K + YPE F + DW + +R+ GTP P+
Sbjct: 468 DYGNSEWKEKARKALARMKIYPETRRAQFEAIIDWLDKK----ACARKVGLGTPLPWDPE 523
Query: 411 WVCKN--------------GHIIPAREEDLPVDPRFDKPPVEKCPVCGAEIEPVTDVLDC 456
WV ++ HI REE +DP P E L+
Sbjct: 524 WVIESLSDSTIYMAYYTISRHINRLREEGR-LDPEKLTPEFFDYIFLEEFSEEREKELE- 581
Query: 457 WVDSSITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKLTG 516
+ I II E K+ FE+ +P R G D+I + IF +
Sbjct: 582 -KKTGIPAEII----------HEMKEEFEYWYPLDWRCSGKDLIPNHLTFFIFNHVAIFR 630
Query: 517 KKPW-KDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWT-ALAPPGEDHPF 574
++ W K I +NG +G+KMSKS GNV+ + I + GAD +RL+ +LA D +
Sbjct: 631 EEHWPKGIAVNGF-GTLEGQKMSKSKGNVLNFIDAIEENGADVVRLYIMSLAEHDSDFDW 689
Query: 575 KWETVDYNFRFLQKVWN-IYRFAERHIKDFDYEKYKDIELEPLDRWILSRLHRIIKFATE 633
+ + V R L++ + I +FAE YE +++EL+ +D+W+L RL++ I+ T+
Sbjct: 690 RRKEVGKLRRQLERFYELISQFAE-------YEAKENVELKTIDKWLLHRLNKAIEGTTK 742
Query: 634 ELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLL 693
LE +R TR + + ++ + +D + R G D+E+K + L +L + L+
Sbjct: 743 ALEEFR----TRTAVQWAFYSIMND-LRWYMRRTEGRDDEAK---RFVLRKLADIWVRLM 794
Query: 694 APFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRK 751
APF PHI EE++ + GE V L WPE ++ +E+ E + + ++ ++++
Sbjct: 795 APFTPHICEELWEKLG----GEGFVSLAKWPEPVDEWWNEEVEVEEDFIKSLIEDIKE 848
>sp|P07813|SYL_ECOLI LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7428464|pir||SYECL leucine--tRNA ligase (EC 6.1.1.4)
[validated] - Escherichia coli
>gi|1651269|dbj|BAA35289.1| (D90704) Leucine-tRNA ligase
(EC 6.1.1.4). [Escherichia coli]
>gi|1786861|gb|AAC73743.1| (AE000168) leucine tRNA
synthetase [Escherichia coli K12]
Length = 860
Score = 125 bits (310), Expect = 3e-27
Identities = 71/182 (39%), Positives = 97/182 (53%), Gaps = 11/182 (6%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+ ++Y P EIE K Q +W E++ ++ DE+K Y + P+ SG LH+GHV ++T D
Sbjct: 1 MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGD 60
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMR 121
+IARY+RM G NVL P G+D GLP E K T P WT+ I M+
Sbjct: 61 VIARYQRMLGKNVLQPIGWDAFGLPAEGAAVK--NNTAPAP---------WTYDNIAYMK 109
Query: 122 KQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKA 181
Q +G+ DW E T Y QK E YKKGL+Y++ V WCP +T LA
Sbjct: 110 NQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANE 169
Query: 182 EV 183
+V
Sbjct: 170 QV 171
>gb|AAB40843.1| (U82598) leucine tRNA synthetase [Escherichia coli]
Length = 907
Score = 125 bits (310), Expect = 3e-27
Identities = 71/182 (39%), Positives = 97/182 (53%), Gaps = 11/182 (6%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+ ++Y P EIE K Q +W E++ ++ DE+K Y + P+ SG LH+GHV ++T D
Sbjct: 48 MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGD 107
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMR 121
+IARY+RM G NVL P G+D GLP E K T P WT+ I M+
Sbjct: 108 VIARYQRMLGKNVLQPIGWDAFGLPAEGAAVK--NNTAPAP---------WTYDNIAYMK 156
Query: 122 KQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKA 181
Q +G+ DW E T Y QK E YKKGL+Y++ V WCP +T LA
Sbjct: 157 NQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANE 216
Query: 182 EV 183
+V
Sbjct: 217 QV 218
>sp|O66680|SYLA_AQUAE LEUCYL-TRNA SYNTHETASE ALPHA SUBUNIT (LEUCINE--TRNA LIGASE ALPHA
SUBUNIT) (LEURS) >gi|7519891|pir||D70331 leucine--tRNA
ligase (EC 6.1.1.4) alpha chain - Aquifex aeolicus
>gi|2983033|gb|AAC06643.1| (AE000685) leucyl-tRNA
synthetase alpha subunit [Aquifex aeolicus]
Length = 634
Score = 124 bits (308), Expect = 5e-27
Identities = 69/180 (38%), Positives = 100/180 (55%), Gaps = 12/180 (6%)
Query: 4 KKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDII 63
K+++P EIE KWQK W E ++K + + Y ++ P + SG +H+GHV ++T D I
Sbjct: 3 KEFNPREIEKKWQKRWEEAGVFKAQEGKPNKFYVLEMFP-YPSGRIHMGHVRNYTIGDAI 61
Query: 64 ARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMRKQ 123
ARY +MRG N+L P G+D GLP E K GI +WT++ I+ M+KQ
Sbjct: 62 ARYLKMRGKNILHPMGWDAFGLPAENAAIKH-GIHP----------AKWTYENIDYMKKQ 110
Query: 124 FIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV 183
+G+S DWD E T D Y Q L+ ++G+ YR+ V WCP +T LA +V
Sbjct: 111 LKILGFSYDWDREIATCDPEYYKWNQWIFLKMLERGIAYRKTAKVNWCPHDQTVLANEQV 170
>emb|CAA29642.1| (X06331) leucyl-tRNA synthetase [Escherichia coli]
Length = 860
Score = 123 bits (305), Expect = 1e-26
Identities = 70/182 (38%), Positives = 96/182 (52%), Gaps = 11/182 (6%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+ ++Y P EIE K Q +W E++ ++ DE+K Y + P+ SG LH+GHV ++T D
Sbjct: 1 MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGD 60
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMR 121
+IARY+ M G NVL P G+D GLP E K T P WT+ I M+
Sbjct: 61 VIARYQHMLGKNVLQPIGWDAFGLPAEGAAVK--NNTAPAP---------WTYDNIAYMK 109
Query: 122 KQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKA 181
Q +G+ DW E T Y QK E YKKGL+Y++ V WCP +T LA
Sbjct: 110 NQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANE 169
Query: 182 EV 183
+V
Sbjct: 170 QV 171
>sp|Q9Z930|SYL_CHLPN LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7437542|pir||C72113 leucine--tRNA ligase (EC
6.1.1.4) [similarity] - Chlamydophila pneumoniae
(strains CWL029 and AR39) >gi|4376420|gb|AAD18306.1|
(AE001602) Leucyl tRNA Synthetase [Chlamydophila
pneumoniae CWL029] >gi|7189530|gb|AAF38433.1| (AE002219)
leucyl-tRNA synthetase [Chlamydophila pneumoniae AR39]
>gi|8978526|dbj|BAA98363.1| (AP002545) leucyl tRNA
synthetase [Chlamydophila pneumoniae J138]
Length = 820
Score = 121 bits (300), Expect = 4e-26
Identities = 73/191 (38%), Positives = 105/191 (54%), Gaps = 16/191 (8%)
Query: 5 KYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGT-LHLGHVLSHTWIDII 63
+YDPN IE KWQ++W E + ++ DE+K Y + P+ SG LH+GH++ +T DI+
Sbjct: 2 RYDPNLIEKKWQQFWKEHRSFQANEDEDKVKYYVLDMFPYPSGAGLHVGHLIGYTATDIV 61
Query: 64 ARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGI-TKDQPEEFLKKCVEWTWQAIEAMRK 122
ARYKR RG++VL P G+D+ GLP E ++ I T P+ +K I +K
Sbjct: 62 ARYKRARGFSVLHPMGWDSFGLPAE-----QYAIRTGTHPKVTTQK-------NIANFKK 109
Query: 123 QFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAE 182
Q +G+S D E+ T D Y QK L Y +GL Y + V +CP+ T L+ E
Sbjct: 110 QLSAMGFSYDEGREFATSDPDYYHWTQKLFLFLYDQGLAYMADMAVNYCPELGTVLSNEE 169
Query: 183 V--GYVEEEGY 191
V G+ E GY
Sbjct: 170 VENGFSIEGGY 180
>pir||E82590 leucyl-tRNA synthetase XF2176 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9107316|gb|AAF84975.1|AE004031_7
(AE004031) leucyl-tRNA synthetase [Xylella fastidiosa]
Length = 887
Score = 120 bits (299), Expect = 5e-26
Identities = 69/178 (38%), Positives = 89/178 (49%), Gaps = 11/178 (6%)
Query: 6 YDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIAR 65
YDP IE Q YW ++ NKP Y + P+ SG LH+GHV ++T D+I+R
Sbjct: 16 YDPQRIESTAQHYWDSTHAFEVNEHSNKPKYYCLSMLPYPSGALHMGHVRNYTIGDVISR 75
Query: 66 YKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMRKQFI 125
YKRM G+NVL P G+D GLP E K K P +WT++ IE MR Q
Sbjct: 76 YKRMTGHNVLQPMGWDAFGLPAENAAIK----NKVAP-------AQWTYKNIERMRTQLK 124
Query: 126 RIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV 183
+GY+ DW E+ T Y Q +KGL YR V W P +T LA +V
Sbjct: 125 SLGYAIDWSREFATCQPDYYVHEQHMFTRLMRKGLAYRRNALVNWDPVDQTVLANEQV 182
>gb|AAG10490.1|AF279106_52 (AF279106) predicted leucyl-tRNA synthetase (leuS) [uncultured
proteobacterium EBAC31A08]
Length = 804
Score = 118 bits (293), Expect = 3e-25
Identities = 131/513 (25%), Positives = 217/513 (41%), Gaps = 91/513 (17%)
Query: 236 GKKVKLPIYEREVPILADEDVDPNFGTGAVYNCTYGDEQDIVWQKRYNLPVIIAINEDGT 295
G V PI ++++P+ V ++GTG V D++D + +YNL + I+ D
Sbjct: 304 GMHVIHPITKKKIPVWIGNFVLLDYGTGVVMGVPAHDQRDFEFASKYNLEIPQVISFDNN 363
Query: 296 MNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLPKKQ 355
NE L V + K I D ++ S A +E+
Sbjct: 364 -NE-------LPVVQKGKLINSD------------------KYDGMDSDEASLEI----- 392
Query: 356 WFIRVKDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDWDWVISRQRVFGTPFPFWVCKN 415
+KD D N + + RL+DW +SRQR +G P P V +N
Sbjct: 393 ----IKDLADA--------NLGEQLIQFRLRDWG--------VSRQRYWGCPIPV-VYEN 431
Query: 416 GHIIPAREEDLPVDPRFDKPPVEKCPVCGAE--------IEPVTDVLDCWVDSSITPLII 467
G E+D+P+ K P+ E ++ TD D ++DSS
Sbjct: 432 GEPRVIDEKDMPIVLPELKKNSAPIPLSQNEDFYNISDRLKRETDTFDTFMDSS---WYY 488
Query: 468 TRWHEAIKGDEEAKKWFEHNFPTALRPQGTD-----IIRTWAFYTIFRTFKLT-GKKPWK 521
R+ + DE K ++ P L G + ++ + F+ R L G +P+K
Sbjct: 489 ARFTSSDNADEMFDKNSKYWLPVDLYIGGIEHAILHLLYSRFFHKALRDMDLVEGNEPFK 548
Query: 522 DIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTAL-APPGEDHPFKWETVD 580
++ GMV DG KMSKS GN V P I KYGAD +RL+ APP + + +V+
Sbjct: 549 KLLTQGMVL-KDGAKMSKSKGNTVDPQSYIEKYGADTVRLYMMFTAPPEQSLEWSESSVE 607
Query: 581 YNFRFLQKVWNIYRFAERHIKDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELE-RYR 639
RF++K+WN+ + K D E+ KD + ++ + + H +K T + E RY
Sbjct: 608 GASRFMKKIWNLV----SNRKFIDLEEPKDPSKQEVE--LRRKSHNTLKKVTNDFETRYS 661
Query: 640 FNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPH 699
FN +M + + + D + E + + + L E + ++ L P PH
Sbjct: 662 FNTAIASIMELV-NFIPDSFKE----------GNASISNQYCLNEAIIIILKTLNPIAPH 710
Query: 700 ITEEIYHAMFKDKIGEKSVHLLSWPEYREDRID 732
I++ +++ + D E+ SWP RE+ ++
Sbjct: 711 ISQHLWNNFYFDFAQEEIES--SWPVLREELLE 741
Score = 113 bits (281), Expect = 7e-24
Identities = 67/179 (37%), Positives = 92/179 (50%), Gaps = 12/179 (6%)
Query: 5 KYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIA 64
+Y+P++IE Q WL+E +K D + Y + P + SG LH+GHV ++T D+I+
Sbjct: 4 EYNPSQIEKTIQDEWLKEDKFKANPDGREKFYCLSMFP-YPSGKLHMGHVRNYTIGDVIS 62
Query: 65 RYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMRKQF 124
RYKRM +NV P G+D GLP E KD WT Q IE M++Q
Sbjct: 63 RYKRMNNFNVFQPMGWDAFGLPAENAAIANKVSPKD-----------WTNQNIEHMKQQL 111
Query: 125 IRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV 183
I +G DW E T + Y Q +FY KGL+YR++ V W P T LA +V
Sbjct: 112 ISLGLGYDWSKELRTCEPEYYKWEQLIFKKFYDKGLVYRKKSLVNWDPVDETVLANEQV 170
>gb|AAG20349.1| (AE005108) leucine-tRNA synthetase; LeuS [Halobacterium sp. NRC-1]
Length = 885
Score = 118 bits (293), Expect = 3e-25
Identities = 66/178 (37%), Positives = 90/178 (50%), Gaps = 12/178 (6%)
Query: 6 YDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIAR 65
YD + IE WQ+ W + +++ D + P Y + P+TSG LH+GHV ++ D AR
Sbjct: 7 YDHHAIEQHWQREWDDADVFRVPDDADDPEYVL-AMFPYTSGQLHMGHVRNYAITDAFAR 65
Query: 66 YKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMRKQFI 125
Y+RM G +VL P G+D+ GLP E + P E WT + I+ MR QF
Sbjct: 66 YRRMDGEDVLHPMGWDSFGLPAENAANER----DTNPRE-------WTERCIDQMRDQFE 114
Query: 126 RIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV 183
+G+ DW+ E T D Y Q EF GL+ R V WCP C T LA +V
Sbjct: 115 ALGFGYDWEREITTCDPDYYKWNQWLFTEFRDAGLVDRRAATVNWCPSCETVLADEQV 172
Score = 108 bits (268), Expect = 2e-22
Identities = 104/378 (27%), Positives = 166/378 (43%), Gaps = 53/378 (14%)
Query: 395 DWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVD-PRFDKP---PVEK--------CPV 442
DW +SRQR +GTP P C++ + ++DLPV+ P F P++ CP
Sbjct: 414 DWGVSRQRYWGTPIPIVHCESCGPVSVPDDDLPVELPEFVHTTGNPLDAAEDWKQTTCPD 473
Query: 443 CGAEIEPVTDVLDCWVDSS--ITPLIITRWHEAIKGDEEAKKWFEHNFPTALRPQGTDII 500
CGA TD +D ++DSS + +A + A W P G +
Sbjct: 474 CGAPAVRETDTMDTFLDSSWYFLRFASPAFDDAPFDTQRANDWL----PVDEYVGGDEHA 529
Query: 501 RTWAFYTIFRTFK------LTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKY 554
Y+ F T L ++P+ + GMV G DG KMSKS N VAP+ ++ +Y
Sbjct: 530 VMHLLYSRFVTKAFADLDMLEHREPFAGLTTQGMVLGEDGTKMSKSKDNGVAPERIVDEY 589
Query: 555 GADALRLWT-ALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIEL 613
GAD RL+T A P + P+ E V + FL+++ ++ R + + D +L
Sbjct: 590 GADTARLFTLRAARPSKAFPWSEEGVRSSHTFLERLLSMARAV-------NADATADGDL 642
Query: 614 EPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIE-MVKYRLYGDDE 672
+P ++ ++ AT + FN + D+ + +V+YR D
Sbjct: 643 DPAAEYVARETAATVQAATTHFDDMEFNRAV---------QAVDELVSLLVRYR----DR 689
Query: 673 ESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYREDRID 732
+ A VA + + LLAP PH+ EE + A+ G+ V +WP D D
Sbjct: 690 DDAAPAVVA--RGVTAAVKLLAPIAPHVAEECWTALG----GDGFVAEAAWPTPDRDVSD 743
Query: 733 -EKAEKLGELARKVVSEM 749
++A L E R+ V ++
Sbjct: 744 HDRATSLIEQTREDVRDI 761
>dbj|BAB17162.1| (AP002868) putative leucyl-tRNA synthetase [Oryza sativa]
Length = 946
Score = 116 bits (289), Expect = 8e-25
Identities = 73/203 (35%), Positives = 104/203 (50%), Gaps = 16/203 (7%)
Query: 4 KKYDPNEIEPKWQKYWLEEKIYK-----YRLDENKPSYAIDTPPPFTSGT-LHLGHVLSH 57
+ Y +EIEP+WQ++W E + ++ + LD +KP I P+ SG LH+GH L +
Sbjct: 63 RAYPYDEIEPRWQRHWEEHRTFRTPDIGHGLDTSKPKCYILDMFPYPSGAGLHVGHPLGY 122
Query: 58 TWIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAI 117
T DI++R+KRM+G+NVL P G+D GLP E + K E + +
Sbjct: 123 TATDILSRFKRMQGFNVLHPMGWDAFGLPAEQYAIETGTHPKITTERNINRF-------- 174
Query: 118 EAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTS 177
+ Q +G+S DWD E T + Y Q L+ K+GL Y+ E PV WCP T
Sbjct: 175 -RSQLQLKSLGFSYDWDREISTTEPTYYKWTQWIFLQLLKRGLAYQAEVPVNWCPALGTV 233
Query: 178 LAKAEV-GYVEEEGYLYYIKLPL 199
LA EV V E G I+ P+
Sbjct: 234 LANEEVIDGVSERGGHPVIRKPM 256
Score = 70.2 bits (169), Expect = 9e-11
Identities = 53/172 (30%), Positives = 79/172 (45%), Gaps = 26/172 (15%)
Query: 536 KMSKSYGNVVAPDEVIPKYGADALRLWTALAPPGEDHPFKWET--VDYNFRFLQKVWNIY 593
KMSKS GNV+ PD+V+ +YGAD+LRL+ P D W T ++ RFL + W +
Sbjct: 712 KMSKSRGNVINPDDVVSEYGADSLRLYEMFMGPLRDSK-TWSTGGIEGVHRFLGRTWRL- 769
Query: 594 RFAERHIKDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWH 653
+ D Y + E L LH+ I TEE++ RFN +M F+
Sbjct: 770 -VVGTPLPDGSYGVGTTVTDEEPTLDQLRVLHKCIARVTEEIQETRFNTAISAMMEFV-- 826
Query: 654 EVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIY 705
Y D + K ++ + +LLL+PF PH+ EE++
Sbjct: 827 -----------NAAYKWDTQPK--------SVIESFILLLSPFAPHMAEELW 859
>pir||G82260 leucyl-tRNA synthetase VC0956 [imported] - Vibrio cholerae (group
O1 strain N16961) >gi|9655415|gb|AAF94118.1| (AE004177)
leucyl-tRNA synthetase [Vibrio cholerae]
Length = 894
Score = 115 bits (286), Expect = 2e-24
Identities = 62/182 (34%), Positives = 99/182 (54%), Gaps = 11/182 (6%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+ ++Y+P +IE K Q++W K + D NK + + P+ SG LH+GHV ++T D
Sbjct: 37 MQEQYNPQDIEHKVQQHWDNNKTFVVSEDPNKEKFYCLSMFPYPSGRLHMGHVRNYTIGD 96
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMR 121
+++R++R++G NVL P G+D GLP E K T P WT++ IE M+
Sbjct: 97 VVSRFQRLQGKNVLQPIGWDAFGLPAENAAVK--NNTAPAP---------WTYENIEYMK 145
Query: 122 KQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKA 181
Q +G+ DW+ E+ T Y Q+ + + KGL+Y++ V WCP +T LA
Sbjct: 146 NQLKLLGFGYDWNREFATCRPEYYRWEQEFFTKLFAKGLVYKKTSSVNWCPNDQTVLANE 205
Query: 182 EV 183
+V
Sbjct: 206 QV 207
>dbj|BAA24690.1| (AB010832) ORF3; putative leucyl-tRNA synthase [Symbiobacterium
thermophilum]
Length = 143
Score = 113 bits (279), Expect = 1e-23
Identities = 58/146 (39%), Positives = 83/146 (56%), Gaps = 12/146 (8%)
Query: 1 MLPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWI 60
M +++D E EP+WQ+ W EE IYK D ++P Y P+ SG LH+GHV ++T +
Sbjct: 1 MAEERFDFREAEPRWQRRWDEEGIYKVERDLSRPKYYALAMFPYPSGKLHMGHVRNYTIV 60
Query: 61 DIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAM 120
D+IARY+RM+GYNVL P GFD+ G+P E + G WT + I M
Sbjct: 61 DVIARYRRMKGYNVLHPMGFDSFGMPAE-NAAIQHGANP----------AVWTRENIAEM 109
Query: 121 RKQFIRIGYSADWDLEYHT-MDDWYK 145
Q ++GYS DW +T +D+Y+
Sbjct: 110 TAQLKQMGYSYDWSRAVYTYREDYYR 135
>pir||F82899 leucyl-tRNA synthetase UU371 [imported] - Ureaplasma urealyticum
>gi|6899353|gb|AAF30780.1|AE002134_4 (AE002134)
leucyl-tRNA synthetase [Ureaplasma urealyticum]
Length = 806
Score = 113 bits (279), Expect = 1e-23
Identities = 66/180 (36%), Positives = 93/180 (51%), Gaps = 13/180 (7%)
Query: 6 YDPNEIEPKWQKYWLEEKIYKYRLDENKPS--YAIDTPPPFTSGTLHLGHVLSHTWIDII 63
Y+ N+IE KWQKYWL+ K +K+ + N P Y +D P + LH+GH +T D+I
Sbjct: 2 YNHNKIEKKWQKYWLDNKTFKFVDNPNNPKKFYVLDMFPYPSGKGLHVGHPKGYTATDVI 61
Query: 64 ARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMRKQ 123
+R+KR+ GY+VL P G+D GLP E + T + P F T Q I+ RKQ
Sbjct: 62 SRFKRLNGYDVLHPIGWDAFGLPAEQYALE----TNNHPHTF-------TQQNIKIFRKQ 110
Query: 124 FIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV 183
IG+ D+D E T D + Q ++ YK L ++ V WC T L+ EV
Sbjct: 111 LQMIGFDFDYDKEVDTTDPQFYQWTQWIFVQLYKHNLAEIQDIDVNWCENLGTVLSNEEV 170
Score = 103 bits (254), Expect = 1e-20
Identities = 97/364 (26%), Positives = 156/364 (42%), Gaps = 64/364 (17%)
Query: 395 DWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPV---------DPRFDKPPVEKCP---- 441
+W+ SRQR +G PFP +N I EDLPV + + P+
Sbjct: 416 NWIFSRQRYWGEPFPVLFDENNQIKII--EDLPVLLPNLNEFKPSKTGESPLANAQEWLY 473
Query: 442 --VCGAEIEPVTDVLDCWVDSSITPLIITRWHE----AIKGDEEAKKWFEHNFPTALRPQ 495
+ G + T+ + W SS L +E EEAKK F P +
Sbjct: 474 VEIDGKKYRRETNTMPQWAGSSWYFLAYILKNEDGSYTPLNSEEAKKRFAKWLPVDVYIG 533
Query: 496 GTDIIRTWAFYT------IFRTFKLTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDE 549
G + Y+ ++ + K+P+ ++ GM+ G + KMSKS GNV+ PD+
Sbjct: 534 GQEHAVLHLLYSRFWHRFLYDIGVVPTKEPFYKVINQGMILGENNEKMSKSKGNVINPDD 593
Query: 550 VIPKYGADALRLWTA-LAPPGEDHPFKWETVDYNFRFLQKVWNIY-RFAERHIKDFDYEK 607
+I +GAD LR++ + P P+ + +D ++L +V+ +Y +E + +
Sbjct: 594 IIASHGADTLRIYEMFMGPLTASLPWNPDGLDAMRKWLDRVYRLYHNLSELEVVE----- 648
Query: 608 YKDIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRL 667
+L L+ I+ H +IK T+ + FN+ E+M F+ V Y
Sbjct: 649 ----DLNKLNEEIIIAYHTLIKNYTKAINEQAFNIAISEMMVFV----------NVLY-- 692
Query: 668 YGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIGEKSVHLLSWPEYR 727
K KV YELL N ++LL+ + PH+ EE+Y + SV L P Y
Sbjct: 693 ---------KNKVINYELLDNFLILLSCYAPHLAEELYSLNHSE-----SVCLQKMPIYD 738
Query: 728 EDRI 731
E +I
Sbjct: 739 EQKI 742
>pir||F81312 leucine--tRNA ligase (EC 6.1.1.4) Cj1091c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968525|emb|CAB73346.1| (AL139077) leucyl-tRNA
synthetase [Campylobacter jejuni]
Length = 809
Score = 113 bits (279), Expect = 1e-23
Identities = 64/178 (35%), Positives = 96/178 (52%), Gaps = 11/178 (6%)
Query: 6 YDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDIIAR 65
Y+ + IE KWQK W E + ++ + D N P I + P+ SG +H+GHV ++T D +AR
Sbjct: 3 YEASLIEKKWQKIWDENEYFEPKDDLNLPKKYILSMFPYPSGRIHMGHVRNYTIGDALAR 62
Query: 66 YKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMRKQFI 125
Y R G+NVL P GFD+ G+P E K K P+ WT++ I M+K+
Sbjct: 63 YYRKIGFNVLHPIGFDSFGMPAENAAIKH----KIHPK-------SWTYENIAYMKKELF 111
Query: 126 RIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV 183
+G+S T D Y Q+ ++ ++KGLIY +E V WC + +T LA +V
Sbjct: 112 SLGFSFSKKRMLATSDPLYTKFEQEFFIKMFEKGLIYTKEANVNWCEQDQTVLANEQV 169
Score = 108 bits (268), Expect = 2e-22
Identities = 89/340 (26%), Positives = 150/340 (43%), Gaps = 46/340 (13%)
Query: 395 DWVISRQRVFGTPFPFWVCKNGHIIPAREEDLPVD-----------PRFDKPPVEK---C 440
DW +SRQR +G P P C++ I+P + E+LP+ DK P K C
Sbjct: 419 DWGVSRQRYWGAPIPMIKCQSCGIVPQKLENLPITLPEDVQITGEGNPLDKHPTWKNCIC 478
Query: 441 PVCGAEIEPVTDVLDCWVDSSITPLIITR----WHEAIKGDEEAKKWFE-HNFPTALRPQ 495
P CG E + +D LD + +SS W E ++ K W + +
Sbjct: 479 PKCGKEAQKESDTLDTFFESSWYFARFASDEKTWQEKALDEKSVKYWMSVDQYIGGIEHA 538
Query: 496 GTDIIRTWAFYTIFRTFK-LTGKKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKY 554
++ F R LT +P+ ++ GMV DG KMSKS GNVV PDE+I KY
Sbjct: 539 ILHLLYARFFQKALRDLGYLTQNEPFDRLLTQGMVL-KDGAKMSKSKGNVVDPDEIIEKY 597
Query: 555 GADALRLWTAL-APPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIEL 613
GAD RL+ APP ++ + + V+ +RF+ K+++ +++K + + K L
Sbjct: 598 GADTARLFILFAAPPAKELEWNDDAVEGAYRFICKLYD----RAQNVKKGELVELKQENL 653
Query: 614 EPLDRWILSRLHRIIKFATEEL-ERYRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDE 672
+++ +++ +K + E + + FN + M + +
Sbjct: 654 NKEEKYARLKVYEALKKSFEVYHQSFAFNTLIAACMEAL-------------------NA 694
Query: 673 ESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDK 712
+ K + E Y ++ +L P +PH+ E+ +FK K
Sbjct: 695 LALCKNEALEQEAFYIILNILEPIIPHVCFELSEELFKCK 734
>sp|P57519|SYL_BUCAI LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|10039108|dbj|BAB13142.1| (AP001119) leucyl-tRNA
synthetase [Buchnera sp. APS]
Length = 859
Score = 112 bits (278), Expect = 2e-23
Identities = 65/182 (35%), Positives = 97/182 (52%), Gaps = 11/182 (6%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+ K+Y P +IE Q++W + K ++ + D K Y P+ SG LH+GHV ++T D
Sbjct: 1 MEKEYSPKKIENYVQEFWKKNKTFEVKEDPKKEKYYCLPMLPYPSGKLHMGHVRNYTISD 60
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMR 121
+I+RY+RM G NVL P G+D GLP E E I ++ + F WT + I+ M+
Sbjct: 61 VISRYQRMLGKNVLQPMGWDAFGLPAE-----EAAI-RNNTDPF-----SWTQKNIKYMK 109
Query: 122 KQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKA 181
KQ +G+S DW E T Y Q + Y+K L+Y++ V WC +T LA
Sbjct: 110 KQLQSLGFSYDWSREITTCHPEYYHWEQWFFTKLYEKKLVYKKNSLVNWCSYDKTVLANE 169
Query: 182 EV 183
+V
Sbjct: 170 QV 171
>pir||F81974 leucine--tRNA ligase (EC 6.1.1.4) NMA0559 [similarity] - Neisseria
meningitidis (group A strain Z2491)
>gi|7379297|emb|CAB83851.1| (AL162753) putative
leucyl-tRNA synthetase [Neisseria meningitidis Z2491]
Length = 910
Score = 108 bits (268), Expect = 2e-22
Identities = 59/182 (32%), Positives = 93/182 (50%), Gaps = 11/182 (6%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+ ++Y P IEP QK W + +I+ D +KP Y + P+ SG LH+GHV ++T D
Sbjct: 1 MQEQYQPAAIEPAAQKKWDDARIFNVSEDASKPKYYCLSMFPYPSGKLHMGHVRNYTIGD 60
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMR 121
+++R+K + G+NV+ P G+D G+P E K WT+ IE M+
Sbjct: 61 VLSRFKLLNGFNVMQPMGWDAFGMPAENAAMKNNVAP-----------AAWTYDNIEYMK 109
Query: 122 KQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKA 181
Q +G++ DW E T Y Q + ++KG++YR+ V W P +T LA
Sbjct: 110 TQLKSLGFAIDWARETATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQTVLANE 169
Query: 182 EV 183
+V
Sbjct: 170 QV 171
>pir||G81029 leucine--tRNA ligase (EC 6.1.1.4) NMB1897 [similarity] - Neisseria
meningitidis (group B strain MD58)
>gi|7227154|gb|AAF42228.1| (AE002539) leucyl-tRNA
synthetase [Neisseria meningitidis MC58]
Length = 876
Score = 108 bits (266), Expect = 4e-22
Identities = 59/182 (32%), Positives = 93/182 (50%), Gaps = 11/182 (6%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+ ++Y P IEP QK W + +I+ D +KP Y + P+ SG LH+GHV ++T D
Sbjct: 1 MQEQYRPAAIEPAAQKKWDDARIFNVSEDASKPKYYCLSMFPYPSGKLHMGHVRNYTIGD 60
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMR 121
+++R+K + G+NV+ P G+D G+P E K WT+ IE M+
Sbjct: 61 VLSRFKLLNGFNVMQPMGWDAFGMPAENAAMKNNVAP-----------AAWTYDNIEYMK 109
Query: 122 KQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKA 181
Q +G++ DW E T Y Q + ++KG++YR+ V W P +T LA
Sbjct: 110 TQLKSLGFAIDWARETATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDPVDQTVLANE 169
Query: 182 EV 183
+V
Sbjct: 170 QV 171
>pir||T01968 isoleucine--tRNA ligase homolog T9A4.4 - Arabidopsis thaliana
>gi|3695406|gb|AAC62806.1| (AF096373) similar to
isoleucyl-tRNA synthetases [Arabidopsis thaliana]
Length = 485
Score = 104 bits (257), Expect = 5e-21
Identities = 95/358 (26%), Positives = 163/358 (44%), Gaps = 30/358 (8%)
Query: 517 KKPWKDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGA-----------DALRLWTAL 565
K +K+++ NG+V DG+KM+K N P EVI +YGA DA+RL+
Sbjct: 10 KPAFKNLICNGLVLAEDGKKMAKKLRNYPPPLEVIDEYGAVSFPYNMLLCCDAVRLYLIN 69
Query: 566 APPGEDHP--FKWETVDYNFRFLQKVW-NIYRFAERHIKDFDYE---KYKDIELEP---- 615
+P P FK E V + + W N YRF ++ K + E + +L
Sbjct: 70 SPVVRAEPLRFKKEGVLGVVKDVFLPWYNAYRFLVQNAKRLETEGGVPFVPTDLATIQSA 129
Query: 616 --LDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYG-DDE 672
LD+WI S +++F EE++ YR + L+ F+ + + Y+ + RL G E
Sbjct: 130 NILDQWIHSATQSLVRFVREEMDAYRLYTVVPRLLKFL-DNLTNIYVRFNRKRLKGRTGE 188
Query: 673 ESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKD-KIGEKSVHLLSWPEYREDRI 731
+ A L+ +L ++APF P TE +Y + K K E+SVH S P RE
Sbjct: 189 DDCHTALSTLFNVLLTSCKVMAPFTPFFTETLYQNLRKACKGSEESVHYCSIPP-REGME 247
Query: 732 DEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESYDDLKLIEKDIAGTMNI 791
E+ E K++ R + + +PL L+ + + ++ D L I + +N+
Sbjct: 248 GERIELSVTRMMKIIDLARNIRERNKLPLKTPLKEMIVVHPDA-DFLNDITGYVLEELNV 306
Query: 792 EKLEIFKGEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKNNAESIAREIKENGKV 849
L L+ ++ +P++ +G R GK + + + +K ++ +E G+V
Sbjct: 307 RSL--VPCNDTLKYASLKAEPDFSVLGKRLGKSMGLVAKEVKEMSQKDILAFEEAGEV 362
>pir||T30889 valine--tRNA ligase (EC 6.1.1.9) - Giardia lamblia
>gi|3219290|dbj|BAA28839.1| (AB008525) Valyl tRNA
Synthetase [Giardia intestinalis]
Length = 1218
Score = 103 bits (254), Expect = 1e-20
Identities = 57/197 (28%), Positives = 98/197 (48%), Gaps = 12/197 (6%)
Query: 3 PKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPS------YAIDTPPPFTSGTLHLGHVLS 56
PK Y+P+ IE W ++W + + +N S + + PPP +G+LH+GH L+
Sbjct: 58 PKAYNPSVIEKSWYEWWEAAGFFSPDMQKNIRSKDSRCKFTLLIPPPNVTGSLHIGHALT 117
Query: 57 HTWIDIIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQP------EEFLKKCV 110
++ D + R+ RM GY L+ G D+ G+ T+ VE+ T+ + E FL++
Sbjct: 118 NSIQDALVRWYRMMGYRTLYLPGLDHAGIATQSVVERNIMKTEGKTRHDLGRERFLERAW 177
Query: 111 EWTWQAIEAMRKQFIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYW 170
W Q + Q +G S DW T+D +S ++ + +GLIYR+ V W
Sbjct: 178 AWKEQFGGRILSQLRILGSSFDWSRSVFTLDPARSRVHNESFVKLFNRGLIYRDSRLVNW 237
Query: 171 CPKCRTSLAKAEVGYVE 187
+T+++ EV Y++
Sbjct: 238 DCSLQTAVSDVEVEYID 254
>pir||E83148 leucyl-tRNA synthetase PA3987 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9950178|gb|AAG07374.1|AE004816_10
(AE004816) leucyl-tRNA synthetase [Pseudomonas
aeruginosa]
Length = 873
Score = 102 bits (251), Expect = 2e-20
Identities = 61/180 (33%), Positives = 88/180 (48%), Gaps = 11/180 (6%)
Query: 4 KKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWIDII 63
++Y P EIE + Q YW E + + R +K + + P+ SG LH+GHV ++T D+I
Sbjct: 3 EQYQPLEIETQAQNYWKEHQSFLVRELPDKEKFYCLSMFPYPSGKLHMGHVRNYTIGDVI 62
Query: 64 ARYKRMRGYNVLFPQGFDNHGLPTELKVEKEFGITKDQPEEFLKKCVEWTWQAIEAMRKQ 123
+RY RM+G NVL P G+D G+P E K WT+ I M+ Q
Sbjct: 63 SRYHRMQGRNVLQPMGWDAFGMPAENAAMKNNVAP-----------AAWTYDNIAYMKSQ 111
Query: 124 FIRIGYSADWDLEYHTMDDWYKAAVQKSLLEFYKKGLIYREEHPVYWCPKCRTSLAKAEV 183
+G + DW E T Y Q ++KG+IYR+ V W P +T LA +V
Sbjct: 112 LDSLGLAIDWSREVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQV 171
>sp|P36432|SYV_HAEPA VALYL-TRNA SYNTHETASE (VALINE--TRNA LIGASE) (VALRS)
>gi|305375|gb|AAA20479.1| (L17342) Valyl-tRNA synthetase
[Haemophilus parainfluenzae]
Length = 378
Score = 90.5 bits (221), Expect = 8e-17
Identities = 82/323 (25%), Positives = 145/323 (44%), Gaps = 19/323 (5%)
Query: 551 IPKYGADALRLW-TALAPPGEDHPFKWETVDYNFRFLQKVWNIYRFAERHIKDFDYEKYK 609
I +G DALR ALA G D + + ++ F K+WN RF + K D +
Sbjct: 37 IAAHGTDALRFTLAALASNGRDINWDMKRLEGYRNFCNKLWNASRFVLTNDK-LDLSQ-G 94
Query: 610 DIELEPLDRWILSRLHRIIKFATEELERYRFNLITRELMTFIWHEVADDYIEMVKYRLYG 669
+IE DRWI S +R ++ L +YRF+L + F W++ D Y+E+ K
Sbjct: 95 EIEFSVADRWIQSEFNRTVESFRSALSQYRFDLCANAIYEFTWNQFCDWYLELTKPVFAN 154
Query: 670 DDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHAMFKDKIG--EKSVHLLSWPEYR 727
+ A L +L ++ L P +P ITEEI+ + K +G S+ L +P+
Sbjct: 155 GNAAQIRAASQTLVHVLEKLLRLAHPLIPFITEEIWQKV-KGFVGITADSIMLQPFPQVE 213
Query: 728 EDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHVAIYALESYDDLKLIEKDIAG 787
E+ D +AE E ++V+ +R + + + L+ ++ S ++ K++EK A
Sbjct: 214 ENGFDPEAEAEIEWLKEVIVAVRNIRAESNIAPSKGLD--LLFRNLSAENAKILEKQTAL 271
Query: 788 TMNIEKLEIFK--GEPQLEERIVEVKPNYKRIGPRYGKLVPRIVEHLKNNAESIAREIKE 845
+ KL+ + + + ++ N + + P G + N +AR KE
Sbjct: 272 LKAMAKLDNVQVLAANETHASVAKLVGNAELLVPMAGFI---------NKEAELARLTKE 322
Query: 846 NGKVEFEIDGEKVELTKEDVMIK 868
K + E+ + +L+ E + K
Sbjct: 323 IEKYQNEVKRIENKLSNEAFVAK 345
>gb|AAB51589.1| (U93308) valyl tRNA synthetase [Arabidopsis thaliana]
Length = 248
Score = 85.4 bits (208), Expect = 3e-15
Identities = 42/113 (37%), Positives = 65/113 (57%), Gaps = 6/113 (5%)
Query: 2 LPKKYDPNEIEPKWQKYWLEEKIYKYRLDENKPSYAIDTPPPFTSGTLHLGHVLSHTWID 61
+ K+Y P +E W +W + ++K +KP + I PPP +G LH+GH L+ D
Sbjct: 136 MAKQYSPATVEKSWYAWWEKSDLFKADAKSSKPPFVIVLPPPNVTGALHIGHALTSAIED 195
Query: 62 IIARYKRMRGYNVLFPQGFDNHGLPTELKVEKEF----GITKDQ--PEEFLKK 108
I R+KRM GYN L+ G D+ G+ T++ VEK+ G+T+ EEF+K+
Sbjct: 196 TIIRWKRMSGYNALWVPGVDHAGIATQVVVEKKIMRDRGMTRHDVGREEFVKE 248
>dbj|BAA28843.1| (AB008529) Valyl tRNA Synthetase [Trichomonas vaginalis]
Length = 368
Score = 83.9 bits (204), Expect = 7e-15
Identities = 87/366 (23%), Positives = 153/366 (41%), Gaps = 49/366 (13%)
Query: 533 DGRKMSKSYGNVVAPDEVIPKYGADALRL-WTALAPPGEDHPFKWETVDYNFRFLQKVWN 591
DGRK G IP+ G DA+RL + A + F K+WN
Sbjct: 14 DGRKADFPNG--------IPQCGTDAMRLALCSFAGANRTANLNVSVIVSYRNFCNKMWN 65
Query: 592 IYRFAERHIKDFDYE-KYKDIELE---PLDRWILSRLHRIIKFATEELERYRFNLITREL 647
RFA + F+ E +KD++ PLD+W L +L IK AT L+ ++ +
Sbjct: 66 AVRFALPNFDKFNPEDSHKDLDASKTTPLDKWALKKLSLAIKAATAGLQDFKMADAVNGM 125
Query: 648 MTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHA 707
F E Y+E +K + GDD +K LYE + + M +L PF+P++TEE++
Sbjct: 126 THFFHDEFCSVYLEGIKPIVNGDDAAAKEVVAAVLYECIESTMRMLHPFMPYVTEELWQH 185
Query: 708 MFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHV 767
+ + + +S+ L +P E+ ++ + + A S R K + + N LE +
Sbjct: 186 LPR-RFNVESIMLAPYPLVNEEWLNYDV-SIVDTAFATASAARSIKKQYNIN-NNNLEAI 242
Query: 768 AIYALESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLE--------ERIVEVKPNY----- 814
+ S D++K I+ + K+++ Q+ VE++ N
Sbjct: 243 IV---TSQDEIKPTIPFISAIGGLGKVDVVAPGTQIAAGYASSVVTETVELRINLKGVVN 299
Query: 815 ---------KRIGP------RYGKLV--PRIVEHLKNNAESIAREIKENGKVEFEIDGEK 857
K++GP +Y + + P +K + + R E KV+ E +
Sbjct: 300 FEKELERLEKKLGPLQQQFQKYEEKISNPNYATKVKPEVQELERSKMEALKVQIEAINKN 359
Query: 858 VELTKE 863
++ K+
Sbjct: 360 IQEVKQ 365
>dbj|BAA28844.1| (AB008530) Valyl tRNA Synthetase [Trichomonas vaginalis]
Length = 368
Score = 83.9 bits (204), Expect = 7e-15
Identities = 88/366 (24%), Positives = 152/366 (41%), Gaps = 49/366 (13%)
Query: 533 DGRKMSKSYGNVVAPDEVIPKYGADALRL-WTALAPPGEDHPFKWETVDYNFRFLQKVWN 591
DGRK G IP+ G DA+RL + A + F K+WN
Sbjct: 14 DGRKADFPNG--------IPQCGTDAMRLALCSFAGANRTANLNVSVIVSYRNFCNKMWN 65
Query: 592 IYRFAERHIKDFDYE-KYKDIELE---PLDRWILSRLHRIIKFATEELERYRFNLITREL 647
RFA + F+ E +KD++ PLD+W L +L IK AT LE ++ +
Sbjct: 66 AVRFALPNFDKFNPEDSHKDLDASKTTPLDKWALKKLSLAIKAATAGLEDFKMADAVNGM 125
Query: 648 MTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFVPHITEEIYHA 707
F E Y+E K + GDD +K LYE + + M +L PF+P++TEE++
Sbjct: 126 THFFHDEFCSVYLEGTKPIVNGDDAAAKEVVAAVLYECIESTMRMLHPFMPYVTEELWQH 185
Query: 708 MFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHGMPLNAKLEHV 767
+ + + +S+ L +P E+ ++ + + A S R K + + N LE +
Sbjct: 186 LPR-RFNVESIMLAPYPLVNEEWLNYDV-SIVDTAFATASAARSIKKQYNIN-NNNLEAI 242
Query: 768 AIYALESYDDLKLIEKDIAGTMNIEKLEIFKGEPQLE--------ERIVEVKPNY----- 814
+ S D++K I+ + K+++ Q+ VE++ N
Sbjct: 243 IV---TSQDEIKPTIPFISAIGGLGKVDVVAPGTQIAAGYASSVVTETVELRINLKGVVD 299
Query: 815 ---------KRIGP------RYGKLV--PRIVEHLKNNAESIAREIKENGKVEFEIDGEK 857
K++GP +Y + + P +K + + R E KV+ E +
Sbjct: 300 FEKELERLEKKLGPLQQQFQKYEEKISNPNYATKVKPEVQELERSKMEALKVQIEAINKN 359
Query: 858 VELTKE 863
++ K+
Sbjct: 360 IQEVKQ 365
>sp|Q09996|SYLC_CAEEL PROBABLE LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS)
>gi|7506790|pir||T19334 hypothetical protein R74.1 -
Caenorhabditis elegans >gi|3874391|emb|CAA86751.1|
(Z46787) contains similarity to Pfam domain: PF00133
(tRNA synthetases class I (I, L, M and V)),
Score=-200.6, E-value=2e-07, N=1~cDNA EST yk47d5.3 comes
from this gene; cDNA EST yk130d10.3 comes from this
gene~cDNA EST yk130d10.5 comes from this gene;>
>gi|3879166|emb|CAA85280.1| (Z36238) contains similarity
to Pfam domain: PF00133 (tRNA synthetases class I (I, L,
M and V)), Score=-200.6, E-value=2e-07, N=1~cDNA EST
yk47d5.3 comes from this gene; cDNA EST yk130d10.3 comes
from this gene~cDNA EST yk130d10.5 comes from this
gene;>
Length = 1186
Score = 76.1 bits (184), Expect = 2e-12
Identities = 108/490 (22%), Positives = 205/490 (41%), Gaps = 46/490 (9%)
Query: 293 DGTMNENAGPYAGLKVEEARKKIAEDLEKMGLLYKKEKIKHRVLRHTERSSCMAPIELLP 352
DG M G YAG K + +K I +DL GL K + + +V+ + +A +
Sbjct: 475 DGVML--VGKYAGKKTADVKKVIQDDLTAEGLATKYVEPEKKVMSRSGDECVVALCD--- 529
Query: 353 KKQWFIRV--KDFTDEIVKVAKEINWYPEDMFLRLKDWAESMDW--DWVISRQRVFGTPF 408
QW++ ++ KV + + + ++ L+ ++DW ++ SR GT
Sbjct: 530 --QWYLNYGEAEWKAAAKKVLEPLRTFNDETRRGLE---TTVDWLHEYACSRSYGLGTKL 584
Query: 409 PFWVCKNGHIIPAREEDLPVDPRFDKPP-VEKCPVCGAEIEPVTDVLDCWVDSSITPLII 467
P+ ++I + + + + +++ G+ + P D D+S + + +
Sbjct: 585 PW---DTQYLIESLSDSTIYNAYYTVAHLLQQGAFDGSVVGPAGIKADQMTDASWSYVFL 641
Query: 468 TRWHEA--IKGDEE----AKKWFEHNFPTALRPQGTDIIRTWAFYTIFRTFKL--TGKKP 519
+++ + +EE +K F + +P +R G D+I Y +F + T
Sbjct: 642 GEIYDSKTMPVEEEKLKSLRKEFMYWYPIDMRASGKDLIGNHLTYLLFNHAAIWPTDTSK 701
Query: 520 W-KDIVINGMVAGPDGRKMSKSYGNVVAPDEVIPKYGADALRLWTALAPPG-EDHPFKWE 577
W K I NG + + KMSKS GN + +E I K+ AD +RL A A G ED F +
Sbjct: 702 WPKGIRANGHLL-LNNEKMSKSTGNFMTLEEAIEKFSADGMRLSLADAGDGLEDANFVYA 760
Query: 578 TVDYNFRFLQKVWNIYRFAERHIKDFDYEKYKDIELEPLDRWILSRLHRIIKFATEELER 637
D + +++ + + + I+ D + + DR + ++ +I + E
Sbjct: 761 MAD---AAILRLFTMIEWIKEMIEQRDAGLLRKDAKKFADRVFANEMNSLIAATEQNYEA 817
Query: 638 YRFNLITRELMTFIWHEVADDYIEMVKYRLYGDDEESKLKAKVALYELLYNVMLLLAPFV 697
F + F + + D Y E+ G DE ++ ++ + ML+L+P
Sbjct: 818 TNFKDALKTGF-FEYQAIRDTYRELCA----GIDEP---MSESLVFRFIETQMLILSPIC 869
Query: 698 PHITEEIYHAMFKDKIGEKSVHLLSWPEYREDRIDEKAEKLGELARKVVSEMRKYKNSHG 757
PHI E I+ + KD + + WP D +DEK + ++E R ++
Sbjct: 870 PHIAEYIWQLLGKDGL----IVNAPWPTV--DPVDEKLAIGARFITESLAEFRARLKTYM 923
Query: 758 MPLNAKLEHV 767
P L+ +
Sbjct: 924 TPKKKALKEI 933
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.320 0.140 0.436
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 373405751
Number of Sequences: 2977
Number of extensions: 17551804
Number of successful extensions: 44618
Number of sequences better than 1.0e-10: 217
Number of HSP's better than 0.0 without gapping: 106
Number of HSP's successfully gapped in prelim test: 111
Number of HSP's that attempted gapping in prelim test: 42845
Number of HSP's gapped (non-prelim): 602
length of query: 891
length of database: 189,106,746
effective HSP length: 54
effective length of query: 837
effective length of database: 156,788,448
effective search space: 131231930976
effective search space used: 131231930976
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 169 (70.2 bits)