BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1268 (purT) DE:PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE 2
(EC 2.1.2.-) (GART 2) (GAR TRANSFORMYLASE 2)
(5'-PHOSPHORIBOSYLGLYCINAMIDE TRANSFORMYLASE 2) (FORMATE-DEPENDENT GAR
TRANSFORMYLASE).
(429 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||C75013 phosphoribosylglycinamide formyltransferase 2 (EC 2.... 877 0.0
pir||C71138 phosphoribosylglycinamide formyltransferase 2 (EC 2.... 855 0.0
sp|Q58881|PURT_METJA PROBABLE PHOSPHORIBOSYLGLYCINAMIDE FORMYLTR... 413 e-114
pir||B83176 phosphoribosylglycinamide formyltransferase 2 PA3751... 390 e-107
pir||D82226 phosphoribosylglycinamide formyltransferase 2 VC1228... 367 e-100
dbj|BAA15657.1| (D90828) Phosphoribosylglycinamide formyltransfe... 350 2e-95
sp|P33221|PURT_ECOLI PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE... 350 2e-95
gb|AAK40393.1| Phosphoribosylglycinamide formyltransferase 2 (pu... 350 2e-95
sp|P39771|PURT_BACSU PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE... 342 3e-93
sp|P46927|PURT_PASHA PROBABLE PHOSPHORIBOSYLGLYCINAMIDE FORMYLTR... 342 3e-93
pir||S47267 5'-phosphoribosyl-1-glycinamide transformylase T - B... 342 6e-93
sp|Q55336|PURT_SYNY3 PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE... 340 1e-92
dbj|BAA15655.1| (D90827) Phosphoribosylglycinamide formyltransfe... 302 5e-81
pir||D70632 phosphoribosylglycinamide formyltransferase 2 (EC 2.... 197 2e-49
sp|P15567|PUR6_SCHPO PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (A... 144 2e-33
pir||H72374 probable phosphoribosylaminoimidazole carboxylase (E... 138 1e-31
sp|P50504|PUR6_DEBOC PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (A... 127 2e-28
sp|Q01930|PUR6_PICME PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (A... 124 2e-27
emb|CAB57994.1| (AJ133372) phosphoribosylaminoimidazole carboxyl... 120 2e-26
sp|Q92210|PUR6_CANAL PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (A... 117 2e-25
sp|O74197|PUR6_CANGA PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (A... 117 2e-25
gb|AAC49742.1| (U75582) phosphoribosylaminoimidazole carboxylase... 115 8e-25
dbj|BAB04343.1| (AP001509) phosphoribosylaminoimidazole carboxyl... 113 4e-24
emb|CAB45017.1| (AJ242839) putative phosphoribosylaminoimidazole... 111 1e-23
pir||T02535 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.2... 111 2e-23
pir||C81132 phosphoribosylaminoimidazole carboxylase, ATPase cha... 109 6e-23
dbj|BAB01486.1| (AB034950) phosphoribosyl-5-aminoimidazole carbo... 108 1e-22
pir||E81892 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.2... 104 2e-21
emb|CAA04376.1| (AJ000883) purK [Lactococcus lactis] 104 3e-21
sp|P12045|PURK_BACSU PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE AT... 102 6e-21
gb|AAK41328.1| Phosphoribosylaminoimidazole carboxylase ATPase s... 102 8e-21
sp|O06457|PURK_SULSO PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE AT... 102 8e-21
gi|6324702 phosphoribosylamino-imidazole-carboxylase; Ade2p [Sac... 100 3e-20
emb|CAB44982.1| (AJ242842) putative phosphoribosylaminoimidazole... 100 4e-20
sp|Q54975|PURK_SYNP7 PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE AT... 100 4e-20
sp|O66608|PURK_AQUAE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE AT... 96 8e-19
pir||B82528 phosphoribosylaminoimidazole carboxylase, ATPase sub... 96 8e-19
sp|P55195|PUR6_VIGAC PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE PR... 94 3e-18
gb|AAG19135.1| (AE005011) phosphoribosylaminoimidazole carboxyla... 94 4e-18
gb|AAC98316.1| (AF112302) phosphoribosylaminoimidazole carboxyla... 93 5e-18
emb|CAC12234.1| (AL445066) phosphoribosylaminoimidazole carboxyl... 93 5e-18
gb|AAB09711.1| (U70673) phosphoribosylaminoimidazole carboxylase... 92 1e-17
sp|Q92233|PUR6_CRYNE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (A... 92 1e-17
pir||B82370 phosphoribosylaminoimidazole carboxylase, ATPase cha... 90 3e-17
gb|AAA34407.1| (M58324) phosphoribosylaminoimidazole carboxylase... 90 6e-17
dbj|BAA22049.1| (AB006759) subunit II of phosphoribosyl aminoimi... 89 1e-16
sp|P96881|PURK_MYCTU PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE AT... 86 6e-16
pir||A75569 probable phosphoribosylaminoimidazole carboxylase (E... 83 7e-15
pir||G82967 phosphoribosylaminoimidazole carboxylase PA5425 [imp... 72 1e-11
sp|P72158|PURK_PSEAE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE AT... 70 4e-11
>pir||C75013 phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-) PAB1268
[similarity] - Pyrococcus abyssi (strain Orsay)
>gi|5459059|emb|CAB50545.1| (AJ248288)
PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE 2 (EC
2.1.2.-) (GART 2) (GAR TRANSFORMYLASE 2)
(5'-PHOSPHORIBOSYLGLYCINAMIDE TRANSFORMYLASE 2)
(FORMATE-DEPENDENT GAR TRANSFORMYLASE). [Pyrococcus
abyssi]
Length = 429
Score = 877 bits (2241), Expect = 0.0
Identities = 429/429 (100%), Positives = 429/429 (100%)
Query: 1 MIEPRDELGTATTDSAQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRS 60
MIEPRDELGTATTDSAQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRS
Sbjct: 1 MIEPRDELGTATTDSAQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRS 60
Query: 61 YVGNMMDKDFLWSVVEREKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRER 120
YVGNMMDKDFLWSVVEREKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRER
Sbjct: 61 YVGNMMDKDFLWSVVEREKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRER 120
Query: 121 LRETLVKEAKVPTSRYMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPK 180
LRETLVKEAKVPTSRYMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPK
Sbjct: 121 LRETLVKEAKVPTSRYMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPK 180
Query: 181 AWEEAKTKARGSAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYH 240
AWEEAKTKARGSAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYH
Sbjct: 181 AWEEAKTKARGSAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYH 240
Query: 241 ASWQPAEISEKAEREVYRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVT 300
ASWQPAEISEKAEREVYRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVT
Sbjct: 241 ASWQPAEISEKAEREVYRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVT 300
Query: 301 LASHPPGFSEFGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLA 360
LASHPPGFSEFGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLA
Sbjct: 301 LASHPPGFSEFGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLA 360
Query: 361 KALSVPNATVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIELRTRSSDWHDQ 420
KALSVPNATVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIELRTRSSDWHDQ
Sbjct: 361 KALSVPNATVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIELRTRSSDWHDQ 420
Query: 421 NYEKRKHLL 429
NYEKRKHLL
Sbjct: 421 NYEKRKHLL 429
>pir||C71138 phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-) PH0318
[similarity] - Pyrococcus horikoshii
>gi|3256709|dbj|BAA29392.1| (AP000002) 433aa long
hypothetical phosphoribosylglycinamide formyl
transferase [Pyrococcus horikoshii]
Length = 433
Score = 855 bits (2184), Expect = 0.0
Identities = 414/429 (96%), Positives = 423/429 (98%)
Query: 1 MIEPRDELGTATTDSAQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRS 60
MI+ RDELGTATTDSAQKILLLGSGELGKEIAIEAQRLGVEV+AVDRYANAPAMQVAHRS
Sbjct: 4 MIKLRDELGTATTDSAQKILLLGSGELGKEIAIEAQRLGVEVVAVDRYANAPAMQVAHRS 63
Query: 61 YVGNMMDKDFLWSVVEREKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRER 120
YVGNMMDKDFLWSVVEREKPDAIIPEIEAINLDALFEFEK+GYFVVPNARATWIAMHRER
Sbjct: 64 YVGNMMDKDFLWSVVEREKPDAIIPEIEAINLDALFEFEKDGYFVVPNARATWIAMHRER 123
Query: 121 LRETLVKEAKVPTSRYMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPK 180
LRETLVKEAKVPTSRYMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPK
Sbjct: 124 LRETLVKEAKVPTSRYMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPK 183
Query: 181 AWEEAKTKARGSAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYH 240
AWEEAKTKARGSAEKIIVEEHIDFDVE+TELAVRHFDENGEIVTTFPKPVGHYQIDGDYH
Sbjct: 184 AWEEAKTKARGSAEKIIVEEHIDFDVEVTELAVRHFDENGEIVTTFPKPVGHYQIDGDYH 243
Query: 241 ASWQPAEISEKAEREVYRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVT 300
ASWQPAEISEKAEREVYRIAKRITDVLGGLG+FGVEMFVKGDKVWANEVSPRPHDTGMVT
Sbjct: 244 ASWQPAEISEKAEREVYRIAKRITDVLGGLGIFGVEMFVKGDKVWANEVSPRPHDTGMVT 303
Query: 301 LASHPPGFSEFGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLA 360
LASHPPGFSEF LHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKV GYSPRFRGL
Sbjct: 304 LASHPPGFSEFALHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVSGYSPRFRGLV 363
Query: 361 KALSVPNATVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIELRTRSSDWHDQ 420
KALSVPNATVRLFGKPEAYVGRRLG+ LAWDKDV+ AK++AEMVAHMIELRTRSSDWHDQ
Sbjct: 364 KALSVPNATVRLFGKPEAYVGRRLGIALAWDKDVEVAKRKAEMVAHMIELRTRSSDWHDQ 423
Query: 421 NYEKRKHLL 429
NYEKRKHLL
Sbjct: 424 NYEKRKHLL 432
>sp|Q58881|PURT_METJA PROBABLE PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE 2 (GART 2)
(GAR TRANSFORMYLASE 2) (5'-PHOSPHORIBOSYLGLYCINAMIDE
TRANSFORMYLASE 2) (FORMATE-DEPENDENT GAR TRANSFORMYLASE)
>gi|2118244|pir||E64485 phosphoribosylglycinamide
formyltransferase 2 (EC 2.1.2.-) MJ1486 [similarity] -
Methanococcus jannaschii >gi|1592123|gb|AAB99496.1|
(U67589) phosphoribosylglycinamide formyltransferase 2
(purT) [Methanococcus jannaschii]
Length = 393
Score = 413 bits (1051), Expect = e-114
Identities = 213/403 (52%), Positives = 281/403 (68%), Gaps = 17/403 (4%)
Query: 8 LGTATTDSAQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMD 67
+GT + K LLLGSGELGKE+ IEAQRLG+E IAVDRY NAPAMQVAH+SYV +M D
Sbjct: 7 IGTPLLKGSIKFLLLGSGELGKEVVIEAQRLGIECIAVDRYQNAPAMQVAHKSYVIDMKD 66
Query: 68 KDFLWSVVEREKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVK 127
D L +++ERE+PD I+PEIEAIN DAL + EK GY V+P A AT I M+RE +R +
Sbjct: 67 YDALMAIIEREEPDYIVPEIEAINTDALIDAEKMGYTVIPTAEATKITMNRELIRRLAAE 126
Query: 128 EAKVPTSRYMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAKT 187
+ + T++Y +A +L+EL +A EK+G PC K IMSSSGKG V+ EDI KAW+ AK
Sbjct: 127 KLGLKTAKYEFADSLEELRDAVEKLGLPCVVKPIMSSSGKGQSVVRSEEDIEKAWKIAKE 186
Query: 188 KARGSAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAE 247
ARG ++IVEE I+FD EIT L R + T F +P+GH QIDGDYH SWQP
Sbjct: 187 GARGIGNRVIVEEFINFDYEITLLTARTAEG-----TKFCEPIGHVQIDGDYHESWQPHN 241
Query: 248 ISEKAEREVYRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPPG 307
+S + + + IAK++TD LGG G+FGVE+FVKGD+V +EVSPRPHDTGMVT+ +
Sbjct: 242 MSAELKEQAQDIAKKVTDALGGYGIFGVELFVKGDEVIFSEVSPRPHDTGMVTMITQE-- 299
Query: 308 FSEFGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLAKALSVPN 367
SEF +H+RA+LGLP+ + ++ P A+HVIKA++ Y+P++ + AL VPN
Sbjct: 300 MSEFEIHVRAILGLPVSTK---------LIHPGASHVIKAEINKYAPKYH-IEDALKVPN 349
Query: 368 ATVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIEL 410
+RLFGKP A VGRR+GV LA+ V++A++ AE AH + +
Sbjct: 350 TKLRLFGKPNAKVGRRMGVALAYADSVEKARELAEKCAHAVRI 392
>pir||B83176 phosphoribosylglycinamide formyltransferase 2 PA3751 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9949920|gb|AAG07138.1|AE004794_3 (AE004794)
phosphoribosylglycinamide formyltransferase 2
[Pseudomonas aeruginosa]
Length = 393
Score = 390 bits (992), Expect = e-107
Identities = 208/403 (51%), Positives = 263/403 (64%), Gaps = 15/403 (3%)
Query: 8 LGTATTDSAQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMD 67
+GT + SA ++LL GSGELGKE+AIE QRLG EVIAVDRY NAPAMQVAHRS+V +M+D
Sbjct: 4 IGTPLSPSATRVLLCGSGELGKEVAIELQRLGCEVIAVDRYGNAPAMQVAHRSHVISMLD 63
Query: 68 KDFLWSVVEREKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVK 127
L +V+E+EKP I+PEIEAI L E E EGY VVP ARA + M+RE +R +
Sbjct: 64 GAALRAVIEQEKPHYIVPEIEAIATATLVELEAEGYTVVPTARAAQLTMNREGIRRLAAE 123
Query: 128 EAKVPTSRYMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAKT 187
E +PTS Y +A T ++ E++GYPC K IMSSSGKG +KGP+D+ AW+ A+
Sbjct: 124 ELGLPTSPYHFADTFEDYRRGVERVGYPCVVKPIMSSSGKGQSVLKGPDDLQAAWDYAQE 183
Query: 188 KARGSAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAE 247
R ++IVE IDFD EIT L VRH D TTF P+GH Q+ GDYH SWQP
Sbjct: 184 GGRAGKGRVIVEGFIDFDYEITLLTVRHVDG-----TTFCAPIGHRQVKGDYHESWQPQA 238
Query: 248 ISEKAEREVYRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPPG 307
+S +A E R+A+ +T+ LGG GLFGVE+FVKGD+VW +EVSPRPHDTG+VTL S
Sbjct: 239 MSAQALAESERVARAVTEALGGRGLFGVELFVKGDQVWFSEVSPRPHDTGLVTLISQ--D 296
Query: 308 FSEFGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLAKALSVPN 367
SEF LH RA+LGLPIP + L P+A+ VI + K F L ALS +
Sbjct: 297 LSEFALHARAILGLPIP--------VIRQLGPSASAVILVEGKSRQVAFANLGAALSEAD 348
Query: 368 ATVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIEL 410
+RLFGKPE RR+GV LA D+ + A+ +A A + +
Sbjct: 349 TALRLFGKPEVDGQRRMGVALARDESIDAARAKATRAAQAVRV 391
>pir||D82226 phosphoribosylglycinamide formyltransferase 2 VC1228 [imported] -
Vibrio cholerae (group O1 strain N16961)
>gi|9655709|gb|AAF94387.1| (AE004202)
phosphoribosylglycinamide formyltransferase 2 [Vibrio
cholerae]
Length = 393
Score = 367 bits (931), Expect = e-100
Identities = 204/402 (50%), Positives = 258/402 (63%), Gaps = 15/402 (3%)
Query: 9 GTATTDSAQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDK 68
GTAT D+A ++LLLGSGELGKE+AIE QRLG+EVIA DRYA+APAMQVAHRS+V +M+D
Sbjct: 5 GTATRDNATRVLLLGSGELGKEVAIECQRLGLEVIACDRYADAPAMQVAHRSHVFDMLDA 64
Query: 69 DFLWSVVEREKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKE 128
D L V++ EKP ++PEIEAI L E E +G VVP A AT + M+RE +R +E
Sbjct: 65 DALQQVIDLEKPHFVVPEIEAIATSKLVELEAQGLNVVPTANATRLTMNREGIRRLAAEE 124
Query: 129 AKVPTSRYMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAKTK 188
+PTS Y +A + + A E IG PC K +MSSSGKG ++ PE I AW+ A+
Sbjct: 125 LGLPTSAYQFADSYESFAAAVETIGLPCVCKPVMSSSGKGQSVIRTPEQIEAAWQYAQQG 184
Query: 189 ARGSAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEI 248
R A ++IVE +DFD EIT L VR D F P+GH Q DGDY SWQP +
Sbjct: 185 GRSGAGRVIVEGFVDFDYEITLLTVRAVDG-----VHFCAPIGHRQEDGDYRESWQPQVM 239
Query: 249 SEKAEREVYRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPPGF 308
SE A + +A+++ + LGG GLFGVE+FVKGDKV NEVSPRPHDTGMVTL S
Sbjct: 240 SENAIKAAEYVAEQVVNALGGYGLFGVELFVKGDKVIFNEVSPRPHDTGMVTLISQE--L 297
Query: 309 SEFGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLAKALSVPNA 368
SEF LH+RA GLPI G+ V P+A+ I + + + +F GL ALS+P+
Sbjct: 298 SEFALHVRAFTGLPI-GQIV-------QYGPSASAAILGQGQSQNIQFNGLDDALSIPHT 349
Query: 369 TVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIEL 410
VRLFGKP+ RRLGV L+ K QEA RA A +++
Sbjct: 350 QVRLFGKPDIAGRRRLGVALSRGKTTQEATDRAIECAKAVKI 391
>dbj|BAA15657.1| (D90828) Phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-)
(GarT 2) (Gar transformylase 2)
(5'-Phosphoribosylglycinamide transformylase 2)
(Formate-dependent GAR transformylase). [Escherichia
coli]
Length = 391
Score = 350 bits (889), Expect = 2e-95
Identities = 201/404 (49%), Positives = 256/404 (62%), Gaps = 16/404 (3%)
Query: 8 LGTATTDSAQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMD 67
LGTA +A +++LLGSGELGKE+AIE QRLGVEVIAVDRYA+APAM VAHRS+V NM+D
Sbjct: 3 LGTALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRYADAPAMHVAHRSHVINMLD 62
Query: 68 KDFLWSVVEREKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVK 127
D L VVE EKP I+PEIEAI D L + E+EG VVP ARAT + M+RE +R +
Sbjct: 63 GDALRRVVELEKPHYIVPEIEAIATDMLIQLEEEGLNVVPCARATKLTMNREGIRRLAAE 122
Query: 128 EAKVPTSRYMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAKT 187
E ++PTS Y +A + EA IGYPC K +MSSSGKG F++ E + +AW+ A+
Sbjct: 123 ELQLPTSTYRFADSESLFREAVADIGYPCIVKPVMSSSGKGQTFIRSAEQLAQAWKYAQQ 182
Query: 188 KARGSAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAE 247
R A ++IVE + FD EIT L V D F PVGH Q DGDY SWQP +
Sbjct: 183 GGRAGAGRVIVEGVVKFDFEITLLTVSAVDG-----VHFCAPVGHRQEDGDYRESWQPQQ 237
Query: 248 ISEKAEREVYRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPPG 307
+S A IA+++ LGG GLFGVE+FV GD+V +EVSPRPHDTGMVTL S
Sbjct: 238 MSPLALERAQEIARKVVLALGGYGLFGVELFVCGDEVIFSEVSPRPHDTGMVTLISQ--D 295
Query: 308 FSEFGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLAKALSVPN 367
SEF LH+RA LGLP+ G G PAA+ VI ++ + F + A+ +
Sbjct: 296 LSEFALHVRAFLGLPVGGIRQYG--------PAASAVILPQLTSQNVTFDNVQNAVGA-D 346
Query: 368 ATVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIELR 411
+RLFGKPE RRLGV LA + V +A +RA+ A ++++
Sbjct: 347 LQIRLFGKPEIDGSRRLGVALATAESVVDAIERAKHAAGQVKVQ 390
>sp|P33221|PURT_ECOLI PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE 2 (GART 2) (GAR
TRANSFORMYLASE 2) (5'-PHOSPHORIBOSYLGLYCINAMIDE
TRANSFORMYLASE 2) (FORMATE-DEPENDENT GAR TRANSFORMYLASE)
>gi|2118243|pir||A54227 phosphoribosylglycinamide
formyltransferase 2 (EC 2.1.2.-) purT [validated] -
Escherichia coli >gi|9954928|pdb|1EYZ|A Chain A,
Structure Of Escherichia Coli Purt-Encoded Glycinamide
Ribonucleotide Transformylase Complexed With Mg And
Amppnp >gi|9954929|pdb|1EYZ|B Chain B, Structure Of
Escherichia Coli Purt-Encoded Glycinamide Ribonucleotide
Transformylase Complexed With Mg And Amppnp
>gi|9954930|pdb|1EZ1|A Chain A, Structure Of Escherichia
Coli Purt-Encoded Glycinamide Ribonucleotide
Transformylase Complexed With Mg, Amppnp, And Gar
>gi|9954931|pdb|1EZ1|B Chain B, Structure Of Escherichia
Coli Purt-Encoded Glycinamide Ribonucleotide
Transformylase Complexed With Mg, Amppnp, And Gar
>gi|304887|gb|AAA23861.1| (L20897) glycinamide
ribonucleotide transformylase [Escherichia coli]
>gi|1788155|gb|AAC74919.1| (AE000279)
phosphoribosylglycinamide formyltransferase 2
[Escherichia coli K12]
Length = 392
Score = 350 bits (889), Expect = 2e-95
Identities = 201/404 (49%), Positives = 256/404 (62%), Gaps = 16/404 (3%)
Query: 8 LGTATTDSAQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMD 67
LGTA +A +++LLGSGELGKE+AIE QRLGVEVIAVDRYA+APAM VAHRS+V NM+D
Sbjct: 4 LGTALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRYADAPAMHVAHRSHVINMLD 63
Query: 68 KDFLWSVVEREKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVK 127
D L VVE EKP I+PEIEAI D L + E+EG VVP ARAT + M+RE +R +
Sbjct: 64 GDALRRVVELEKPHYIVPEIEAIATDMLIQLEEEGLNVVPCARATKLTMNREGIRRLAAE 123
Query: 128 EAKVPTSRYMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAKT 187
E ++PTS Y +A + EA IGYPC K +MSSSGKG F++ E + +AW+ A+
Sbjct: 124 ELQLPTSTYRFADSESLFREAVADIGYPCIVKPVMSSSGKGQTFIRSAEQLAQAWKYAQQ 183
Query: 188 KARGSAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAE 247
R A ++IVE + FD EIT L V D F PVGH Q DGDY SWQP +
Sbjct: 184 GGRAGAGRVIVEGVVKFDFEITLLTVSAVDG-----VHFCAPVGHRQEDGDYRESWQPQQ 238
Query: 248 ISEKAEREVYRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPPG 307
+S A IA+++ LGG GLFGVE+FV GD+V +EVSPRPHDTGMVTL S
Sbjct: 239 MSPLALERAQEIARKVVLALGGYGLFGVELFVCGDEVIFSEVSPRPHDTGMVTLISQ--D 296
Query: 308 FSEFGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLAKALSVPN 367
SEF LH+RA LGLP+ G G PAA+ VI ++ + F + A+ +
Sbjct: 297 LSEFALHVRAFLGLPVGGIRQYG--------PAASAVILPQLTSQNVTFDNVQNAVGA-D 347
Query: 368 ATVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIELR 411
+RLFGKPE RRLGV LA + V +A +RA+ A ++++
Sbjct: 348 LQIRLFGKPEIDGSRRLGVALATAESVVDAIERAKHAAGQVKVQ 391
>gb|AAK40393.1| Phosphoribosylglycinamide formyltransferase 2 (purT) [Sulfolobus
solfataricus]
Length = 409
Score = 350 bits (888), Expect = 2e-95
Identities = 181/403 (44%), Positives = 264/403 (64%), Gaps = 11/403 (2%)
Query: 7 ELGTATTDSAQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMM 66
E+GT + ++KILLLGSGELGKE+AIEAQR+G+EV+A+DRY APAM VAHR YV +MM
Sbjct: 14 EIGTPLFEGSKKILLLGSGELGKEMAIEAQRMGLEVVALDRYDLAPAMHVAHRKYVVDMM 73
Query: 67 DKDFLWSVVEREKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLV 126
+ + + +VV+RE+PDAII EIEAIN DAL E E G+ VVPNA A M+R LR
Sbjct: 74 NPNAIKAVVKRERPDAIIAEIEAINTDALIELESNGFRVVPNANAVKACMNRIELRRFAA 133
Query: 127 KEAKVPTSRYMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAK 186
++ K+PT++Y +A +E+ AC+ IG+PC K MSSSG G V E++ +A+ E+
Sbjct: 134 EKLKLPTTKYAFAENEEEVKRACKDIGFPCLIKPEMSSSGHGHVLVNKIENVEEAYRESI 193
Query: 187 TKARGSAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPA 246
+ ARG + ++IVEE + D E+T L R+ + I+T +P+ H + Y SW P+
Sbjct: 194 SHARGKSRRVIVEEFVKIDTELTVLTYRYHSNSDSIITKTIEPIEHKRPSYYYVESWHPS 253
Query: 247 EISEKAEREVYRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPP 306
+S+ + IA+++ + LGGLG++GVE+ V G+++ +EV+PRPHDTG+VTLAS
Sbjct: 254 NVSQGVKETARGIAQKVAEELGGLGIYGVEIIVSGNRILFSEVAPRPHDTGLVTLAS--S 311
Query: 307 GFSEFGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKG-YSPRFRGLAKALSV 365
+EF +H+R+ +GLP P ++ PAA+HVI A+ + + P+F + KA+ +
Sbjct: 312 DINEFQIHVRSAIGLPTPE--------VKLVSPAASHVILAQTENVWGPKFLNIEKAMEI 363
Query: 366 PNATVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMI 408
P VRLFGKP Y RR+GVVLA V+EA ++ + +I
Sbjct: 364 PGVQVRLFGKPVTYEKRRMGVVLATGNSVEEALEKVRKASSII 406
>sp|P39771|PURT_BACSU PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE 2 (GART 2) (GAR
TRANSFORMYLASE 2) (5'-PHOSPHORIBOSYLGLYCINAMIDE
TRANSFORMYLASE 2) (FORMATE-DEPENDENT GAR TRANSFORMYLASE)
>gi|7428337|pir||E69685 phosphoribosylglycinamide
formyltransferase 2 (EC 2.1.2.-) purT [validated] -
Bacillus subtilis >gi|2632509|emb|CAB12017.1| (Z99105)
phosphoribosylglycinamide formyltransferase 2 [Bacillus
subtilis] >gi|3599645|dbj|BAA33120.1| (AB006424)
PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE 2 [Bacillus
subtilis]
Length = 384
Score = 342 bits (869), Expect = 3e-93
Identities = 184/396 (46%), Positives = 248/396 (62%), Gaps = 15/396 (3%)
Query: 16 AQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVV 75
++K+LLLGSGELGKE+ IEAQRLGV+ +AVD Y +APAMQVAH SYV +M+D + + +++
Sbjct: 4 SKKVLLLGSGELGKEVVIEAQRLGVQTVAVDSYEHAPAMQVAHNSYVVDMLDPEQIRTII 63
Query: 76 EREKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKVPTSR 135
E+E PD I+PE+EAI D L + E+EG+ V+PNARA + M RE +R + + T+
Sbjct: 64 EKENPDLIVPEVEAIATDELLKLEEEGFHVIPNARAAKLTMDREGIRRLAAETLGLATAG 123
Query: 136 YMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAEK 195
Y +A T DE +A +IG+PC K +MSSSGKG + D+ WE A R +
Sbjct: 124 YEFANTYDEFIQAAAQIGFPCVVKPLMSSSGKGQSVCRSEADLESCWETAMEGGRVKNGR 183
Query: 196 IIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAERE 255
+IVEE I F+ EIT L VR NG T F +P+GH Q DGDY SWQP +++E+ E
Sbjct: 184 VIVEEFIPFESEITLLTVRAV--NG---TAFCEPIGHVQKDGDYIESWQPHDMTEQQIEE 238
Query: 256 VYRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPPGFSEFGLHL 315
IAK ITD LGG GLFGVE+F+ D+V+ +EVSPRPHDTG+VTL + SEF LH+
Sbjct: 239 AKHIAKTITDELGGYGLFGVELFLAKDRVYFSEVSPRPHDTGLVTLVTQ--NLSEFALHV 296
Query: 316 RAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLAKALSVPNATVRLFGK 375
RA+LG PI L P A+ +KA + GL AL+VP VR+FGK
Sbjct: 297 RAILGFPITE--------ITQLSPGASRPLKAPEELADYTVEGLENALAVPKTQVRVFGK 348
Query: 376 PEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIELR 411
P GRR+ V L+ V+ A++ A+ + L+
Sbjct: 349 PITKAGRRMAVALSAADSVETARENAKKALDQLILK 384
>sp|P46927|PURT_PASHA PROBABLE PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE 2 (GART 2)
(GAR TRANSFORMYLASE 2) (5'-PHOSPHORIBOSYLGLYCINAMIDE
TRANSFORMYLASE 2) (FORMATE-DEPENDENT GAR TRANSFORMYLASE)
(MEMBRANE PROTEIN ANTIGEN 1) >gi|1075457|pir||A56691
phosphoribosylglycinamide formyltransferase 2 (EC
2.1.2.-) [similarity] - Pasteurella haemolytica
>gi|469475|gb|AAB28915.1| (S68137) Mpa1=PurK homolog
[Pasteurella haemolytica, A1, Peptide, 392 aa]
Length = 392
Score = 342 bits (869), Expect = 3e-93
Identities = 185/404 (45%), Positives = 258/404 (63%), Gaps = 16/404 (3%)
Query: 8 LGTATTDSAQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMD 67
+GT +A K+++LGSGELGKE+ IE Q LGVEVIAVDRY NAPA QVAHR+Y +M+D
Sbjct: 4 IGTPLRTNATKVMMLGSGELGKEVVIELQPLGVEVIAVDRYDNAPAQQVAHRAYTISMLD 63
Query: 68 KDFLWSVVEREKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVK 127
+ L +VE+EKPD I+PE+EAI L E E+EGY V+P A+AT + M+RE +R +
Sbjct: 64 GNALRDLVEKEKPDFIVPEVEAIATATLVELEQEGYNVIPTAKATQLTMNREGIRRLAAE 123
Query: 128 EAKVPTSRYMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAKT 187
E + TS Y + ++ +A ++IG PC K IMSSSG G +K DI +AW+ ++
Sbjct: 124 ELGLKTSPYRFVDNFEQFQQAIQEIGIPCVVKPIMSSSGHGQSVIKSEADIQQAWDYSQQ 183
Query: 188 KARGSAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAE 247
R ++IVE I FD EIT+L VRH +G + ++ H Q+DGDY SWQP +
Sbjct: 184 GGRAGGGRVIVEGFIKFDYEITQLTVRHI--HGIVFSSH----RHIQVDGDYRESWQPQQ 237
Query: 248 ISEKAEREVYRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPPG 307
+S+ A ++ A++IT LGG G+FGVE+FV GD++ NEVSPRPHDTG+VT+AS
Sbjct: 238 MSDIALKKAQETAEKITSALGGRGIFGVELFVCGDEIIFNEVSPRPHDTGIVTMASQE-- 295
Query: 308 FSEFGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLAKALSVPN 367
S+F LH RA+LGLPIP + YR + PAA+ I + K + RF G+ K L+
Sbjct: 296 LSQFALHARAILGLPIP----EIYR----ISPAASKAIVVEGKSDNVRFGGVDKVLAEIG 347
Query: 368 ATVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIELR 411
+RLFGK E RRLGV+LA D++ A + + ++++
Sbjct: 348 TNIRLFGKGEVNGHRRLGVILARDENTVRALETSRRAYDKLDIQ 391
>pir||S47267 5'-phosphoribosyl-1-glycinamide transformylase T - Bacillus
subtilis >gi|534939|emb|CAA55557.1| (X78962)
5'-phosphoribosyl-1-glycinamide transformylase T
[Bacillus subtilis]
Length = 384
Score = 342 bits (867), Expect = 6e-93
Identities = 184/396 (46%), Positives = 248/396 (62%), Gaps = 15/396 (3%)
Query: 16 AQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVV 75
++K+LLLGSGELGKE+ IEAQRLGV+ +AVD Y +APAMQVAH SYV +M+D + + +++
Sbjct: 4 SKKVLLLGSGELGKEVVIEAQRLGVQTVAVDSYEHAPAMQVAHNSYVVDMLDPEQIRTII 63
Query: 76 EREKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKVPTSR 135
E+E PD I+PE+EAI D L + E+EG+ V+PNARA + M RE +R + + T+
Sbjct: 64 EKENPDLIVPEVEAIATDELLKLEEEGFHVIPNARAAKLTMDREGIRRLAAETLGLATAG 123
Query: 136 YMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAEK 195
Y +A T DE +A +IG+PC K +MSSSGKG + D+ WE A R +
Sbjct: 124 YEFANTYDEFIQAAAQIGFPCVVKPLMSSSGKGQSVCRSEADLESCWETAMEGGRVKNGR 183
Query: 196 IIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAERE 255
+IVEE I F+ EIT L VR NG T F +P+GH Q DGDY SWQP +++E+ E
Sbjct: 184 VIVEEFIPFESEITLLTVRAV--NG---TAFCEPIGHVQKDGDYIESWQPHDMTEQQIEE 238
Query: 256 VYRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPPGFSEFGLHL 315
IAK ITD LGG GLFGVE+F+ D+V+ +EVSPRPHDTG+VTL + SEF LH+
Sbjct: 239 ANDIAKTITDELGGYGLFGVELFLAKDRVYFSEVSPRPHDTGLVTLVTQ--NLSEFALHV 296
Query: 316 RAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLAKALSVPNATVRLFGK 375
RA+LG PI L P A+ +KA + GL AL+VP VR+FGK
Sbjct: 297 RAILGFPITE--------ITQLSPGASRPLKAPEELADYTVEGLENALAVPKTQVRVFGK 348
Query: 376 PEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIELR 411
P GRR+ V L+ V+ A++ A+ + L+
Sbjct: 349 PITKAGRRMAVALSAADSVETARENAKKALDQLILK 384
>sp|Q55336|PURT_SYNY3 PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE 2 (GART 2) (GAR
TRANSFORMYLASE 2) (5'-PHOSPHORIBOSYLGLYCINAMIDE
TRANSFORMYLASE 2) (FORMATE-DEPENDENT GAR TRANSFORMYLASE)
>gi|7436520|pir||S74842 phosphoribosylglycinamide
formyltransferase 2 (EC 2.1.2.-) slr0861 [similarity] -
Synechocystis sp. (strain PCC 6803)
>gi|558138|gb|AAA85911.1| (L36958) glycinamide
ribonucleotide transformylase [Synechocystis sp.]
>gi|1652885|dbj|BAA17803.1| (D90909) glycinamide
ribonucleotide transformylase [Synechocystis sp.]
Length = 391
Score = 340 bits (864), Expect = 1e-92
Identities = 194/396 (48%), Positives = 253/396 (62%), Gaps = 14/396 (3%)
Query: 17 QKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVE 76
Q LLLGSGELGKE I AQRLG VIAVDRY +APAMQVA + V +M+D + L +VV+
Sbjct: 9 QTFLLLGSGELGKEFTIAAQRLGNRVIAVDRYPDAPAMQVAQVAEVISMLDGNALEAVVK 68
Query: 77 REKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKVPTSRY 136
+ +PD I+PE+EAI + L E E GY V+P A+AT + M+R+R+RE ++ V T+RY
Sbjct: 69 KYQPDWIVPEVEAIRTEKLLELEAGGYRVIPTAQATNLTMNRDRIRELAAQQLGVRTARY 128
Query: 137 MYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAEKI 196
YAT+L EL E + IG+P K +MSSSGKG V ++ +AW A ARG K+
Sbjct: 129 NYATSLAELEEVSQAIGFPNVVKPVMSSSGKGQSVVNNAGEVQQAWSAAIAGARGDQTKV 188
Query: 197 IVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAEREV 256
IVEE I F++EIT L +R + GE T F P+GH Q GDY SWQPA ++++ +
Sbjct: 189 IVEEFIPFELEITLLTIRQW--QGE--TLFCDPIGHRQERGDYQESWQPAPLTQRQLAQA 244
Query: 257 YRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPPGFSEFGLHLR 316
IAK +TD LGG G+FGVE F+ ++V +E+SPRPHDTGMVTL S +EF LHLR
Sbjct: 245 QAIAKTVTDALGGAGIFGVEFFITPEEVIFSELSPRPHDTGMVTLISQ--NLNEFELHLR 302
Query: 317 AVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLAKALSVPNATVRLFGKP 376
A+LGLPIP G PAA+ VI A G + GLA+AL+ VRLFGKP
Sbjct: 303 AILGLPIPQIKQTG--------PAASAVILALEAGEKLSYAGLAEALTESGTDVRLFGKP 354
Query: 377 EAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIELRT 412
A RRLGV LA + V A++ A+ VA + ++T
Sbjct: 355 NARPHRRLGVALAQAESVDAARRLAQTVAEKVIVQT 390
>dbj|BAA15655.1| (D90827) Phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-)
(GarT 2) (Gar transformylase 2)
(5'-Phosphoribosylglycinamide transformylase 2)
(Formate-dependent GAR transformylase). [Escherichia
coli]
Length = 295
Score = 302 bits (765), Expect = 5e-81
Identities = 162/296 (54%), Positives = 199/296 (66%), Gaps = 5/296 (1%)
Query: 8 LGTATTDSAQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMD 67
LGTA +A +++LLGSGELGKE+AIE QRLGVEVIAVDRYA+APAM VAHRS+V NM+D
Sbjct: 3 LGTALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRYADAPAMHVAHRSHVINMLD 62
Query: 68 KDFLWSVVEREKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVK 127
D L VVE EKP I+PEIEAI D L + E+EG VVP ARAT + M+RE +R +
Sbjct: 63 GDALRRVVELEKPHYIVPEIEAIATDMLIQLEEEGLNVVPCARATKLTMNREGIRRLAAE 122
Query: 128 EAKVPTSRYMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAKT 187
E ++PTS Y +A + EA IGYPC K +MSSSGKG F++ E + +AW+ A+
Sbjct: 123 ELQLPTSTYRFADSESLFREAVADIGYPCIVKPVMSSSGKGQTFIRSAEQLAQAWKYAQQ 182
Query: 188 KARGSAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAE 247
R A ++IVE + FD EIT L V D F PVGH Q DGDY SWQP +
Sbjct: 183 GGRAGAGRVIVEGVVKFDFEITLLTVSAVDG-----VHFCAPVGHRQEDGDYRESWQPQQ 237
Query: 248 ISEKAEREVYRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLAS 303
+S A IA+++ LGG GLFGVE+FV GD+V +EVSPRPHDTGMVTL S
Sbjct: 238 MSPLALERAQEIARKVVLALGGYGLFGVELFVCGDEVIFSEVSPRPHDTGMVTLIS 293
>pir||D70632 phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-) Rv0389
[similarity] - Mycobacterium tuberculosis (strain H37RV)
>gi|3261704|emb|CAB06595.1| (Z84725) purT [Mycobacterium
tuberculosis]
Length = 419
Score = 197 bits (495), Expect = 2e-49
Identities = 136/414 (32%), Positives = 204/414 (48%), Gaps = 33/414 (7%)
Query: 11 ATTDSAQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDF 70
A ++++LLGS E +E+AI Q LG EVIAVD Y APA ++A +S V M D +
Sbjct: 20 AAPQDVRRVMLLGSAEPSRELAIALQGLGAEVIAVDGYVGAPAHRIADQSVVVTMTDAEE 79
Query: 71 LWSVVEREKPDAIIPEIEAINLDALFEFEK---EGYFVVPNARATWIAMHRERLRETLVK 127
L +V+ R +PD ++ A+++DAL E+ E +VPNARA RE LR
Sbjct: 80 LTAVIRRLQPDFLVTVTAAVSVDALDAVEQADGECTELVPNARAVRCTADREGLRRLAAD 139
Query: 128 EAKVPTSRYMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEA-- 185
+ +PT+ + + +L EL G+P + +G+GS V GP ++ AW+ A
Sbjct: 140 QLGLPTAPFWFVGSLGELQAVAVHAGFPLLVSPVAGVAGQGSSVVAGPNEVEPAWQRAAG 199
Query: 186 ---KTKARGSAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHAS 242
+ + G + ++ E ++ + +T + V NG ++ F P+GH D S
Sbjct: 200 HQVQPQTGGVSPRVCAESVVEIEFLVTMIVVCSQGPNGPLI-EFCAPIGHRDADAGELES 258
Query: 243 WQPAEISEKAEREVYRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLA 302
WQP ++S A IA RI LGG G+FGVE+ + GD+V+ +V+ P + VT+
Sbjct: 259 WQPQKLSTAALDAAKSIAARIVKALGGRGVFGVELMINGDEVYFADVTVCPAGSAWVTVR 318
Query: 303 SHPPGFSEFGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIK------AKVKGYSPRF 356
S S F L RA+LGL + M+ P A VI G +P
Sbjct: 319 SQ--RLSVFELQARAILGLAVD---------TLMISPGAARVINPDHTAGRAAVGAAPPA 367
Query: 357 RGLAKALSVPNATVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIEL 410
L AL VP + V +F GR LGV LA +V A++RA VA + +
Sbjct: 368 DALTGALGVPESDVVIF-------GRGLGVALATAPEVAIARERAREVASRLNV 414
>sp|P15567|PUR6_SCHPO PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (AIR CARBOXYLASE) (AIRC)
>gi|68001|pir||DEZPP phosphoribosylaminoimidazole
carboxylase (EC 4.1.1.21) - fission yeast
(Schizosaccharomyces pombe) >gi|4902|emb|CAA32650.1|
(X14488) phosphoribosylaminoimidazole carboxylase (AA 1
- 552) [Schizosaccharomyces pombe]
>gi|173342|gb|AAA35285.1| (M37264)
phosphoribosylaminoimidazole carboxylase (ade6)
[Schizosaccharomyces pombe] >gi|4176553|emb|CAA22866.1|
(AL035259) phosphoribosylaminoimidazole carboxylase
[Schizosaccharomyces pombe]
Length = 552
Score = 144 bits (359), Expect = 2e-33
Identities = 118/397 (29%), Positives = 196/397 (48%), Gaps = 34/397 (8%)
Query: 17 QKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQV-AHRSYV-GNMMDKDFLWSV 74
Q + +LG G+LG+ + A RL ++ I +D AN+PA Q+ R ++ + D D ++
Sbjct: 5 QVVGILGGGQLGRMMVEAAHRLNIKCIILDA-ANSPAKQIDGGREHIDASFTDPD---AI 60
Query: 75 VEREKPDAIIP-EIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKVPT 133
VE K ++ EIE IN DAL K V + AT + + L++ ++ K+
Sbjct: 61 VELSKKCTLLTTEIEHINTDALAAVTKS--VAVEPSPATLRCIQDKYLQKQHLQVFKIAL 118
Query: 134 SRYMYATTLDELYEACEKIGYPCHTKA-IMSSSGKGSYFVKGPEDIPKAWEEAKTKARGS 192
+ A + + +A ++ GYP K+ ++ G+G+Y V P +IP A KA G
Sbjct: 119 PEFCDAPDQESVEKAGQEFGYPFVLKSKTLAYDGRGNYVVHQPSEIPTA-----IKALGD 173
Query: 193 AEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKA 252
+ VE+ + F +EI + VR D V +P Q D H + PA +
Sbjct: 174 -RPLYVEKFVPFSMEIAVMVVRSLDGK---VYAYPT-TETIQKDNVCHLVYAPARLPFSI 228
Query: 253 EREVYRIAKRITDVLGGLGLFGVEMFV--KGDKVWANEVSPRPHDTGMVTLASHPPGFSE 310
++ +A G G++GVEMFV G+ + NE++PRPH++G T+ + P S+
Sbjct: 229 QQRAQTLAMDAVRTFEGAGIYGVEMFVLQDGETILLNEIAPRPHNSGHYTIEACPT--SQ 286
Query: 311 FGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYS-PRF--RGLAKALSVPN 367
F HLRA+ GLP + L + TH + + G P + + ++LS+P
Sbjct: 287 FEAHLRAICGLPFS-------EINTQLSTSTTHALMVNILGTDDPDYVSKIAKRSLSIPG 339
Query: 368 ATVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMV 404
AT+ L+GK E+ GR++G V QE ++R +M+
Sbjct: 340 ATLHLYGKAESRKGRKMGHVTIISDSPQECERRYQML 376
>pir||H72374 probable phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)
carbon dioxide-fixation chain TM0447 [similarity] -
Thermotoga maritima (strain MSB8)
>gi|4980965|gb|AAD35542.1|AE001723_12 (AE001723)
phosphoribosylaminoimidazole carboxylase, ATPase subunit
[Thermotoga maritima]
Length = 380
Score = 138 bits (344), Expect = 1e-31
Identities = 109/392 (27%), Positives = 189/392 (47%), Gaps = 39/392 (9%)
Query: 17 QKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVE 76
+KI ++G G+LGK + +EA+++G VI +D +PA QVA V D + + +V+
Sbjct: 2 KKIGIIGGGQLGKMMTLEAKKMGFYVIVLDPTPRSPAGQVADEQIVAGFFDSERIEDLVK 61
Query: 77 REKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKVPTSRY 136
D ++E I++ L + EGY + P+ I + +E L K +P Y
Sbjct: 62 GS--DVTTYDLEHIDVQTLKKLYNEGYKIHPSPYTLEIIQDKFVQKEFLKKNG-IPVPEY 118
Query: 137 MYATTLDELYEACEKIGYPCHTKAIMSS-SGKGSYFVKGPEDIPKAWEEAKTKARGSAEK 195
+ +L + G+P KA G+G + +K +D+ A + +
Sbjct: 119 ---KLVKDLESDVREFGFPVVQKARKGGYDGRGVFIIKNEKDLENAIK----------GE 165
Query: 196 IIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYH---ASWQPAEISEKA 252
+EE ++ + E+ + R +E GEI PV D D + PA I EK
Sbjct: 166 TYLEEFVEIEKELAVMVAR--NEKGEIAC---YPVVEMYFDEDANICDTVIAPARIEEKY 220
Query: 253 EREVYRIAKRITDVLGGLGLFGVEMFV-KGDKVWANEVSPRPHDTGMVTLASHPPGFSEF 311
+ IA + + L G+G+FG+EMF+ K ++ NE++PRPH++G T+ + S+F
Sbjct: 221 SKIAREIATSVVEALEGVGIFGIEMFLTKQGEILVNEIAPRPHNSGHYTIEACVT--SQF 278
Query: 312 GLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGY--SPRFRGLAKALSVPNAT 369
H+RA++ LP+ +LIPA + + +GY P GL +AL++ +
Sbjct: 279 EQHIRAIMNLPLGST--------ELLIPAVMVNLLGE-EGYYGKPALIGLEEALAIEGLS 329
Query: 370 VRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRA 401
+ +GK E R++G D+DV+ A ++A
Sbjct: 330 LHFYGKKETRPYRKMGHFTVVDRDVERALEKA 361
>sp|P50504|PUR6_DEBOC PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (AIR CARBOXYLASE) (AIRC)
>gi|2133234|pir||S60392 phosphoribosylaminoimidazole
carboxylase (EC 4.1.1.21) - yeast (Schwanniomyces
occidentalis) >gi|995583|gb|AAA96380.1| (U23210)
phosphoribosylaminoimidazole carboxylase [Debaryomyces
occidentalis]
Length = 557
Score = 127 bits (317), Expect = 2e-28
Identities = 112/393 (28%), Positives = 191/393 (48%), Gaps = 33/393 (8%)
Query: 21 LLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYV-GNMMDKDFLWSVVE-RE 78
+LG G+LG+ I A RL ++ + +D N+PA Q+ +V G+ D L S+++ E
Sbjct: 8 ILGGGQLGRMIVEAANRLNIKTVVLD-VPNSPAKQINSNEHVDGSFTD---LKSIIQLAE 63
Query: 79 KPDAIIPEIEAINLDAL-FEFEKEGYFVVPNARATWIAMHRERLRETLVKEA-KVPTSRY 136
K D + EIE ++++AL + EK G + P + + +E L++ V S
Sbjct: 64 KCDILTVEIEHVDVEALKYVKEKFGVEIYPLPDTIKLIQDKYLQKEHLIQHGISVTESVA 123
Query: 137 MYATTLDELYEACEKIGYPCHTKA-IMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAEK 195
+ + L E K YP K+ ++ G+G+Y VK E IP+A E K +
Sbjct: 124 VPSNDEQSLIEIGNKFNYPFMLKSRTLAYDGRGNYVVKTKESIPEALEFLKDRP------ 177
Query: 196 IIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAERE 255
+ E+ F+ E+ + VR + GE+ +P V + H + PA +S+ +
Sbjct: 178 LYAEKWCPFNKELAVMVVRSIE--GEVFA-YPT-VETIHKNNICHVVYAPARVSDSIAVK 233
Query: 256 VYRIAKRITDVLGGLGLFGVEMF-VKGDKVWANEVSPRPHDTGMVTLASHPPGFSEFGLH 314
+AK G G+FGVEMF + +++ NE++PRPH++G T+ + S+F H
Sbjct: 234 ASVLAKNAVKSFPGCGIFGVEMFLLPNNEILINEIAPRPHNSGHYTIDACVT--SQFEAH 291
Query: 315 LRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGL---AKALSVPNATVR 371
+RAV+GLP+P + F L T+ I V G + L +AL PNA+V
Sbjct: 292 VRAVVGLPMP-------KNFTSLSTTTTNAIMLNVLGDEESNKELEICRRALETPNASVY 344
Query: 372 LFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMV 404
L+GK R++G + +++ + R + +
Sbjct: 345 LYGK-STRPNRKMGHINIVSSSMEDCESRLDYI 376
>sp|Q01930|PUR6_PICME PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (AIR CARBOXYLASE) (AIRC)
>gi|481666|pir||S39112 phosphoribosylaminoimidazole
carboxylase (EC 4.1.1.21) - yeast (Pichia methanolica)
>gi|457702|emb|CAA54041.1| (X76529) 5-aminoimidazole
ribonucleotide-carboxilase [Pichia methanolica]
Length = 543
Score = 124 bits (309), Expect = 2e-27
Identities = 109/413 (26%), Positives = 193/413 (46%), Gaps = 34/413 (8%)
Query: 16 AQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQV-AHRSYV-GNMMDKDFLWS 73
+Q + +LG G+LG+ I A RL ++ + ++ APA Q+ A ++ G+ D +
Sbjct: 3 SQTVGILGGGQLGRMIVEAAHRLNIKTVILENGDQAPAKQINALDDHIDGSFNDPKAIAE 62
Query: 74 VVEREKPDAIIPEIEAINLDALFEFEK-EGYFVVPNARATWIAMHRERLRETLVKEAKVP 132
+ K D + EIE ++ DAL E +K G + P+ + + +E L+K
Sbjct: 63 LA--AKCDVLTVEIEHVDTDALVEVQKATGIKIFPSPETISLIKDKYLQKEHLIKNGIAV 120
Query: 133 TSRYMYATTLDELYEACEKIGYPCHTKA-IMSSSGKGSYFVKGPEDIPKAWEEAKTKARG 191
++ L E K G+P K+ M+ G+G++ VK IP+A + +
Sbjct: 121 AESCSVESSAASLEEVGAKYGFPYMLKSRTMAYDGRGNFVVKDKSYIPEALKVLDDR--- 177
Query: 192 SAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEK 251
+ E+ F E+ + VR D V ++P +Q + H + PA +++
Sbjct: 178 ---PLYAEKWAPFSKELAVMVVRSIDGQ---VYSYPTVETIHQ-NNICHTVFAPARVNDT 230
Query: 252 AEREVYRIAKRITDVLGGLGLFGVEMF-VKGDKVWANEVSPRPHDTGMVTLASHPPGFSE 310
+++ +A G G+FGVEMF ++ + NE++PRPH++G T+ + S+
Sbjct: 231 VQKKAQILADNAVKSFPGAGIFGVEMFLLQNGDLLVNEIAPRPHNSGHYTIDACVT--SQ 288
Query: 311 FGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKG---YSPRFRGLAKALSVPN 367
F H+RA+ GLP+P + F L +T I V G + F+ +AL P+
Sbjct: 289 FEAHVRAITGLPMP-------KNFTCLSTPSTQAIMLNVLGGDEQNGEFKMCKRALETPH 341
Query: 368 ATVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIELRTRSSDWHDQ 420
A+V L+GK GR++G + + + + ++R H IE T S +Q
Sbjct: 342 ASVYLYGK-TTRPGRKMGHINIVSQSMTDCERR----LHYIEGTTNSIPLEEQ 389
>emb|CAB57994.1| (AJ133372) phosphoribosylaminoimidazole carboxylase
[Zygosaccharomyces rouxii] >gi|11414818|emb|CAC17413.1|
(AJ251115) phosphoribosyl-aminoimidazole carboxylase
[Zygosaccharomyces rouxii]
Length = 570
Score = 120 bits (299), Expect = 2e-26
Identities = 110/401 (27%), Positives = 192/401 (47%), Gaps = 35/401 (8%)
Query: 15 SAQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQV-AHRSYVGNMMDKDFLWS 73
++Q + +LG G+LG+ + A RL ++ I +D N+PA Q+ A +V +
Sbjct: 2 NSQTVGILGGGQLGRMVVEAANRLNIKTIILDA-PNSPAKQINALNEHVDGSFSNP---A 57
Query: 74 VVER--EKPDAIIPEIEAINLDALFEFEKE--GYFVVPNARATWIAMHRERLRETLV-KE 128
+E+ EK D + EIE +++ L + + + + P+ + + + LV
Sbjct: 58 DIEKLAEKCDVLTVEIEHVDVPTLKKLQSKHPNLKIYPSPETIGLIQDKYVQKNHLVANN 117
Query: 129 AKVPTSRYMYATTLDELYEACEKIGYPCHTKA-IMSSSGKGSYFVKGPEDIPKAWEEAKT 187
V S + +TT + L A ++GYP K+ M+ G+G++ VK E IPKA E K
Sbjct: 118 IAVAESIPIESTTSEGLALAGRQLGYPYMLKSRTMAYDGRGNFVVKSEESIPKALEFLKD 177
Query: 188 KARGSAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAE 247
+ + E+ F E+ + VR D V ++P V D + PA
Sbjct: 178 R------PLYAEKWAPFTKELAVMIVRSIDGR---VFSYP-TVETIHKDNICFLCYAPAR 227
Query: 248 ISEKAEREVYRIAKRITDVLGGLGLFGVEMF-VKGDKVWANEVSPRPHDTGMVTLASHPP 306
+ + + + +A+ G G+FGVEMF ++ ++ NE++PRPH++G T+ +
Sbjct: 228 VPDSVQLKAKLLAENAVRAFPGCGIFGVEMFYLETGELLINEIAPRPHNSGHYTIDACIT 287
Query: 307 GFSEFGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGL---AKAL 363
S+F HLRA+L LP+P + F L + T+ I V G + + L +AL
Sbjct: 288 --SQFEAHLRAILDLPMPKD-------FSSLSTSCTNAIMLNVLGEDVKNQELQTCERAL 338
Query: 364 SVPNATVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMV 404
P A+V L+GK E+ R+LG + ++E ++R +
Sbjct: 339 ETPGASVYLYGK-ESRPKRKLGHINVVTSSMEECERRLSFI 378
>sp|Q92210|PUR6_CANAL PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (AIR CARBOXYLASE) (AIRC)
>gi|1658379|gb|AAC49755.1| (U69606)
phosphoribosylaminoimidazole carboxylase [Candida
albicans]
Length = 568
Score = 117 bits (291), Expect = 2e-25
Identities = 113/398 (28%), Positives = 194/398 (48%), Gaps = 40/398 (10%)
Query: 21 LLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQV-AHRSYV-GNMMDKDFLWSVVERE 78
+LG G+LG+ I A RL ++ + +D A +PA Q+ A +V G+ + D + + E
Sbjct: 8 ILGGGQLGRMIVEAAHRLNIKTVILDA-AKSPAKQINALDDHVDGSFTNYDSIVKLAE-- 64
Query: 79 KPDAIIPEIEAINLDALFEFEKE--GYFVVPNARATWIAMHRERLRETLVK-EAKVPTSR 135
K D + EIE +++DAL + +++ + P + + + L+K + V S
Sbjct: 65 KADVLTVEIEHVDVDALIKVQEKFPKVEIYPLPETIRLIQDKYLQKNHLIKHDVAVTESV 124
Query: 136 YMYATTLDELYEACEKIGYPCHTKA-IMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAE 194
+ T+D+L EK GYP K+ ++ G+G++ VK KA E K +
Sbjct: 125 AVETNTVDDLLHIGEKFGYPYMLKSRTLAYDGRGNFVVKDKSYCEKALEFLKDRP----- 179
Query: 195 KIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAER 254
+ E+ F E+ + VR + GE+ +P V + +H + PA I + +
Sbjct: 180 -LYAEKWCPFTKELAVMVVRSLE--GEVFA-YPT-VETIHENNIWHLVYAPARIPDTLGQ 234
Query: 255 EVYRIAKRITDVLGGLGLFGVEMF-VKGDKVWANEVSPRPHDTGMVTLASHPPGFSEFGL 313
+ +AK G G+FGVEMF ++ +++ NE++PRPH++G T+ + S+F
Sbjct: 235 KASILAKNAVKSFPGCGIFGVEMFLLENNELLINEIAPRPHNSGHYTIDACVT--SQFEA 292
Query: 314 HLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKG--YSPRFRG--LAKALSVPNAT 369
H+RAV GLP+P G+ F I T+ I V G +P +AL P+A+
Sbjct: 293 HVRAVTGLPMP----KGFTEFSTSI---TNAIMLNVLGDKATPNKESEICRRALETPHAS 345
Query: 370 VRLFGK---PEAYVGRRLGVVLAWDKDVQEAKKRAEMV 404
V L+GK PE R++G + +Q+A+ R +
Sbjct: 346 VYLYGKATRPE----RKMGHINVVTSSMQDAESRLSYI 379
>sp|O74197|PUR6_CANGA PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (AIR CARBOXYLASE) (AIRC)
>gi|3342244|gb|AAC27548.1| (AF030388) aminoimidazole
ribonucleotide carboxylase [Candida glabrata]
Length = 570
Score = 117 bits (291), Expect = 2e-25
Identities = 102/394 (25%), Positives = 186/394 (46%), Gaps = 33/394 (8%)
Query: 21 LLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRS--YVGNMMDKDFLWSVVERE 78
+LG G+LG+ I A RL ++ + +D N+PA Q+ + S G+ +K+ + ++
Sbjct: 8 ILGGGQLGRMIVEAANRLNIKTLILDA-PNSPAKQITNASDHVDGSFANKEDIEALAA-- 64
Query: 79 KPDAIIPEIEAINLDALFEFEKE--GYFVVPNARATWIAMHRERLRETLVKEAKVPTSRY 136
K D + EIE ++++AL E +K+ + P + + ++ LVK
Sbjct: 65 KCDVMTVEIEHVDVNALKEVQKQFPKLEIYPTPETIGLIQDKYVQKQHLVKNRIPVVPSI 124
Query: 137 MYATTLDELYEACEKIGYPCHTKA-IMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAEK 195
+ + L + +GYP K+ ++ G+G++ VK EDI K E +
Sbjct: 125 TVENSKESLIKTGSSLGYPFVLKSRTLAYDGRGNFVVKSEEDIEKGLEFLANRP------ 178
Query: 196 IIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAERE 255
+ E+ F E++ + +R D V ++P V + H + PA + + + +
Sbjct: 179 LYAEKWASFKKELSVMIIRSLDGR---VYSYPI-VETIHKNNVCHLCYVPARVPDSVQHK 234
Query: 256 VYRIAKRITDVLGGLGLFGVEMF-VKGDKVWANEVSPRPHDTGMVTLASHPPGFSEFGLH 314
+A+ G G+FGVEMF + D + NE++PRPH++G T+ + S+F H
Sbjct: 235 AKLMAENAIKSFPGCGIFGVEMFLLDDDSIVLNEIAPRPHNSGHYTI--NACVVSQFEAH 292
Query: 315 LRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKG----YSPRFRGLAKALSVPNATV 370
LRA+L LP+P + F L +T+ I + G + +AL+ P A+V
Sbjct: 293 LRAILDLPMP-------KNFTSLSTNSTNAIMLNLLGDPETKDKELQICERALNTPGASV 345
Query: 371 RLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMV 404
L+GK E+ R++G + ++E KR + +
Sbjct: 346 YLYGK-ESKPNRKVGHINIVCSSMKECDKRLQFI 378
>gb|AAC49742.1| (U75582) phosphoribosylaminoimidazole carboxylase [Candida
albicans]
Length = 568
Score = 115 bits (286), Expect = 8e-25
Identities = 112/398 (28%), Positives = 192/398 (48%), Gaps = 40/398 (10%)
Query: 21 LLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQV-AHRSYV-GNMMDKDFLWSVVERE 78
+LG G+LG+ I A RL ++ + +D A +PA Q+ A +V G+ + D + + E
Sbjct: 8 ILGGGQLGRMIVEAAHRLNIKTVILDA-AKSPAKQINALDDHVDGSFTNYDSIVKLAE-- 64
Query: 79 KPDAIIPEIEAINLDALFEFEKE--GYFVVPNARATWIAMHRERLRETLVK-EAKVPTSR 135
K D + EIE +++DAL + +++ + P + + + L+K + V S
Sbjct: 65 KADVLTVEIEHVDVDALIKVQEKFPKVEIYPLPETIRLIQDKYLQKNHLIKHDVAVTESV 124
Query: 136 YMYATTLDELYEACEKIGYPCHTKA-IMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAE 194
+ T+D+L EK GYP K+ ++ G+G++ VK KA E K +
Sbjct: 125 AVETNTVDDLLHIGEKFGYPYMLKSRTLAYDGRGNFVVKDKSYCEKALEFLKDRP----- 179
Query: 195 KIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAER 254
+ E+ F E+ + VR + GE+ +P V + H + PA I + +
Sbjct: 180 -LYAEKWCPFTKELAVMVVRSLE--GEVFA-YPT-VETIHENNICHLVYAPARIPDTLGQ 234
Query: 255 EVYRIAKRITDVLGGLGLFGVEMF-VKGDKVWANEVSPRPHDTGMVTLASHPPGFSEFGL 313
+ +AK G G+FGVEMF ++ +++ NE++PRPH++G T+ + S+F
Sbjct: 235 KASILAKNAVKSFLGCGIFGVEMFLLENNELLINEIAPRPHNSGHYTIDACVT--SQFEA 292
Query: 314 HLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKG----YSPRFRGLAKALSVPNAT 369
H+RAV GLP+P G+ F I T+ I V G + +AL P+A+
Sbjct: 293 HVRAVTGLPMP----KGFTEFSTSI---TNAIMLNVLGDKATPNKELEICRRALETPHAS 345
Query: 370 VRLFGK---PEAYVGRRLGVVLAWDKDVQEAKKRAEMV 404
V L+GK PE R++G + +Q+A+ R +
Sbjct: 346 VYLYGKTTRPE----RKMGHINVVTSSMQDAESRLSYI 379
>dbj|BAB04343.1| (AP001509) phosphoribosylaminoimidazole carboxylase II [Bacillus
halodurans]
Length = 379
Score = 113 bits (280), Expect = 4e-24
Identities = 101/395 (25%), Positives = 180/395 (45%), Gaps = 34/395 (8%)
Query: 14 DSAQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWS 73
+ + I +LG G+LG+ +A+ A+ +G + +D + P QVA D +
Sbjct: 5 EPGKTIGILGGGQLGRMMALAARAMGYRIAVLDPNPDGPCAQVADVVIEAAYDDMEAAKK 64
Query: 74 VVEREKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKVPT 133
+V D + E E +NLD E++G + A + HR +ET + +P
Sbjct: 65 LV--SVSDVVTYEFENVNLDVANYIEQKG-CLPQGANLLRVTQHRAVEKET-ITTLGLPV 120
Query: 134 SRYMYATTLDELYEACEKIGYPCHTKAIMSS-SGKGSYFVKGPEDIPKAWEEAKTKARGS 192
+ Y Y + E + IG+P K GKG V+ +++ A++E K
Sbjct: 121 ALYKYVNEAPDFIELAQTIGFPAVLKTCRGGYDGKGQRVVRTVDELKSAYDELKL----- 175
Query: 193 AEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKA 252
A ++++E + FD EI+ + R+ + TFP ++ + H S PA I +
Sbjct: 176 AGELVLEAWVPFDKEISVIVARNERND---TKTFPVAENIHEAN-ILHQSIVPARIGDDL 231
Query: 253 EREVYRIAKRITDVLGGLGLFGVEMFV--KGDKVWANEVSPRPHDTGMVTLASHPPGFSE 310
+ ++A R+ + L +G VEMFV GD ++ NE++PRPH++G T+ + S+
Sbjct: 232 RDKAEQLAIRLAEGLNLIGTLAVEMFVTTSGD-IYINELAPRPHNSGHYTIEACET--SQ 288
Query: 311 FGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLAKALS-VPNAT 369
F H+RA+ G P+ G+ + V+ + G G+ +S + +A
Sbjct: 289 FEQHVRAICGWPL------GH------VGLYKPVVMGNLLG--EHLPGVLNEISEMKDAK 334
Query: 370 VRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMV 404
+ L+GK EA R++G + D+ A R +
Sbjct: 335 LHLYGKAEAKEKRKMGHITVLADDLNRAIDRVGQI 369
>emb|CAB45017.1| (AJ242839) putative phosphoribosylaminoimidazole carboxylase
[Neisseria gonorrhoeae] >gi|5051444|emb|CAB44952.1|
(AJ242840) putative phosphoribosylaminoimidazole
carboxylase [Neisseria gonorrhoeae]
Length = 378
Score = 111 bits (276), Expect = 1e-23
Identities = 114/388 (29%), Positives = 180/388 (46%), Gaps = 37/388 (9%)
Query: 21 LLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVEREKP 80
+LG G+LG+ A+ A+ +G +V +D NAPA + A R D+ L E K
Sbjct: 14 ILGGGQLGRMFAVAAKTMGYKVTVLDPDPNAPAAEFADRHLCAPFDDRAAL---DELAKC 70
Query: 81 DAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKVPTSRYMYAT 140
A+ E E +N DA+ K V P+ IA +R + + +++A + T+ Y
Sbjct: 71 AAVTTEFENVNADAMRSLAKHTN-VSPSGDCVSIAQNRIQ-EKAWIRKAGLQTAPYQAVC 128
Query: 141 TLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAEKIIVEE 200
+++ EA + A + GKG VK +++ A+ E G + ++E+
Sbjct: 129 KAEDITEASAQFLPGILKTATLGYDGKGQIRVKTLDELKAAFAE-----HGGVD-CVLEK 182
Query: 201 HIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAEREVYRIA 260
+D EI+ + R DEN V TF P + +G S PA +S +++ + A
Sbjct: 183 MVDLRGEISVIVCRLNDEN---VQTFD-PAENIHENGILAYSIVPARLSADVQQQARQTA 238
Query: 261 KRITDVLGGLGLFGVEMFVKGD--KVWANEVSPRPHDTGMVTLASHPPGFSEFGLHLRAV 318
+R+ D L +G+ VEMFV GD ++ NE +PR H++G T+ + +F +R +
Sbjct: 239 QRLADELDYVGVLAVEMFVVGDTHELLVNETAPRTHNSGHHTIDACAA--DQFQQQVRIM 296
Query: 319 LGLPIPGEWVDGYRLFPMLIPAATHVIKAKV---KGYSPRFRGLAKALSVPNATVRLFGK 375
LP P + +L P I V G P + L S PNA + L+GK
Sbjct: 297 CNLP-PADT-------KLLSPCCMANILGDVWQEDGGEPDWLPLQ---SRPNAHLHLYGK 345
Query: 376 PEAYVGRRLG--VVLAWDKDV--QEAKK 399
A GR++G VL D D QEAKK
Sbjct: 346 KTAQKGRKMGHFTVLTTDSDTAFQEAKK 373
>pir||T02535 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) -
Arabidopsis thaliana >gi|3236251|gb|AAC23639.1|
(AC004684) putative phosphoribosylaminoimidazole
carboxylase [Arabidopsis thaliana]
Length = 645
Score = 111 bits (274), Expect = 2e-23
Identities = 98/375 (26%), Positives = 180/375 (47%), Gaps = 21/375 (5%)
Query: 16 AQKIL-LLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSV 74
++KI+ +LG G+LG+ + A +L ++V+ +D N A +++ G+M+D +
Sbjct: 89 SEKIVGVLGGGQLGRMLCQAASQLAIKVMILDPSKNCSASALSY----GHMVDSFDDSAT 144
Query: 75 VER--EKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKVP 132
VE ++ + EIE +++D L + EK+G P A I + +++ + +P
Sbjct: 145 VEEFAKRCGVLTVEIEHVDVDTLEKLEKQGVDCQPKASTIRIIQDKY-MQKVHFSQHGIP 203
Query: 133 TSRYMYATTLDELYEACEKIGYPCHTKAI-MSSSGKGSYFVKGPEDIPKAWEEAKTKARG 191
+M + ++ +A E GYP K+ ++ G+G+ +++ A T G
Sbjct: 204 LPEFMEISDIEGARKAGELFGYPLMIKSKRLAYDGRGNAVANNQDEL----SSAVTALGG 259
Query: 192 SAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEK 251
+ + +E+ F E+ + R D + + +P V D H PA++ K
Sbjct: 260 FSRGLYIEKWAPFVKELAVIVARGRDGS---MVCYPV-VETIHRDNICHIVKAPADVPWK 315
Query: 252 AEREVYRIAKRITDVLGGLGLFGVEMFVKGD-KVWANEVSPRPHDTGMVTLASHPPGFSE 310
+ +A++ L G G+F VE+F+ D ++ NEV+PRPH++G T+ S+
Sbjct: 316 INKLATDVAQKAVGSLEGAGVFAVELFLTEDSQILLNEVAPRPHNSGHQTIECCYT--SQ 373
Query: 311 FGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLAKALSVPNATV 370
F HLRAV+GLP+ + I VI + G+ R +A+AL +P A+V
Sbjct: 374 FEQHLRAVVGLPLGDPSMRTPASIMYNILGEDDVIDGEA-GFKLAHRLIARALCIPGASV 432
Query: 371 RLFGKPEAYVGRRLG 385
+ KPE R++G
Sbjct: 433 HWYDKPEMRKQRKMG 447
>pir||C81132 phosphoribosylaminoimidazole carboxylase, ATPase chain NMB1019
[imported] - Neisseria meningitidis (group B strain
MD58) >gi|7226258|gb|AAF41419.1| (AE002452)
phosphoribosylaminoimidazole carboxylase, ATPase subunit
[Neisseria meningitidis MC58]
Length = 378
Score = 109 bits (270), Expect = 6e-23
Identities = 109/396 (27%), Positives = 184/396 (45%), Gaps = 53/396 (13%)
Query: 21 LLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVEREKP 80
+LG G+LG+ + A+ +G +V +D +APA + A R D+ L E K
Sbjct: 14 ILGGGQLGRMFTVAAKTMGYKVTVLDPDPDAPAAEFADRHLCAPFNDQAAL---DELAKC 70
Query: 81 DAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKVPTSRYMYAT 140
A+ E E +N DA+ F + V P+ IA +R + + +++A + T+ Y
Sbjct: 71 AAVTTEFENVNADAM-RFLAKHTNVSPSGDCVAIAQNRIQ-EKAWIRKAGLQTAPYQVVC 128
Query: 141 TLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAEKIIVEE 200
+++ EA + A + GKG VK +++ A+ E G + ++E+
Sbjct: 129 KAEDITEASAQFLPGILKTATLGYDGKGQIRVKTLDELKAAFAE-----HGGVD-CVLEK 182
Query: 201 HIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAEREVYRIA 260
+D EI+ + R ++N V TF P + +G S PA +S +++ ++A
Sbjct: 183 MVDLRSEISVIVCRLNNDN---VQTFD-PAENIHENGILAYSIVPARLSADVQQQARQMA 238
Query: 261 KRITDVLGGLGLFGVEMFVKGD--KVWANEVSPRPHDTGMVTLASHPPGFSEFGLHLRAV 318
+R+ D L +G+ VEMFV GD ++ NE++PRPH++G T+ + +F +R +
Sbjct: 239 QRLADELDYVGVLAVEMFVVGDTHELVVNEIAPRPHNSGHHTIDA--CAADQFQQQVRIM 296
Query: 319 LGLPIPGEWVDGYRLFPMLIPAATHVIKA-----------KVKGYSPRFRGLAKALSVPN 367
LP PA T ++ + + G P + L S PN
Sbjct: 297 CNLP----------------PADTKLLSSCCMANILGDVWQEDGGEPDWLPLQ---SHPN 337
Query: 368 ATVRLFGKPEAYVGRRLG--VVLAWDKDV--QEAKK 399
A + L+GK A+ GR++G VL D D QEAKK
Sbjct: 338 AHLHLYGKKTAHKGRKMGHFTVLTTDSDTAFQEAKK 373
>dbj|BAB01486.1| (AB034950) phosphoribosyl-5-aminoimidazole carboxylase [Candida
boidinii]
Length = 572
Score = 108 bits (267), Expect = 1e-22
Identities = 100/398 (25%), Positives = 181/398 (45%), Gaps = 32/398 (8%)
Query: 16 AQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQV-AHRSYV-GNMMDKDFLWS 73
++ I +LG G+LG+ + A RL ++ + ++ +PA Q+ A +++ G+ D + +
Sbjct: 3 SKTIGILGGGQLGRMLVEAASRLNIKTVILENGDQSPAKQINASSTHIDGSFNDPEAIAK 62
Query: 74 VVEREKPDAIIPEIEAINLDALFEF-EKEGYFVVPNARATWIAMHRERLRETLVKEAKVP 132
+ D + EIE +N +AL + + G + P + + +E L+K
Sbjct: 63 LA--AACDIMTVEIEHVNTEALQKISDSTGLPIYPTPATLSVIKDKYLQKEHLIKHGIAV 120
Query: 133 TSRYMYATTLDELYEACEKIGYPCHTKA-IMSSSGKGSYFVKGPEDIPKAWEEAKTKARG 191
+ + L + E+ GYP KA ++ G+G++ VK + I +A E +
Sbjct: 121 AESVAVESNEESLLKVGEQFGYPFMLKARTLAYDGRGNFVVKSQDKIKEAIEFLGDR--- 177
Query: 192 SAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEK 251
+ E+ F E+ + VR D N V ++P V D H + PA + +
Sbjct: 178 ---PLYAEKWAPFTKELAVMVVRSVDGN---VYSYP-TVETIHRDNICHTVFAPARVQDS 230
Query: 252 AEREVYRIAKRITDVLGGLGLFGVEMFV--KGDKVWANEVSPRPHDTGMVTLASHPPGFS 309
++ +A G G+FGVEMF+ GD + NE++PRPH++G T+ + S
Sbjct: 231 ILKKAQILADNAVKSFDGAGIFGVEMFLLPSGD-LLVNEIAPRPHNSGHYTIDACVT--S 287
Query: 310 EFGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGY---SPRFRGLAKALSVP 366
+F +RA+ GLP+P F T+ I V G + F +AL P
Sbjct: 288 QFEALIRALAGLPMPDN-------FTKFSTPQTNAIMLNVLGTDIPNSEFELCRRALETP 340
Query: 367 NATVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMV 404
N++V L+GK R++G + +Q+ ++R +
Sbjct: 341 NSSVYLYGK-TTRPKRKMGHINIVSGSMQDCERRLRYI 377
>pir||E81892 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) ATPase chain
NMA1245 [imported] - Neisseria meningitidis (group A
strain Z2491) >gi|5051454|emb|CAB44975.1| (AJ242841)
putative phosphoribosylaminoimidazole carboxylase
[Neisseria meningitidis] >gi|7379927|emb|CAB84500.1|
(AL162755) putative phosphoribosylaminoimidazole
carboxylase ATPase subunit [Neisseria meningitidis
Z2491]
Length = 378
Score = 104 bits (257), Expect = 2e-21
Identities = 105/396 (26%), Positives = 183/396 (45%), Gaps = 53/396 (13%)
Query: 21 LLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVEREKP 80
+LG G+LG+ + A+ +G +V +D NAPA + A R D ++ E K
Sbjct: 14 ILGGGQLGRMFTVAAKTMGYKVTVLDPNPNAPAAEFADRHLCAPF---DNQTALEELAKC 70
Query: 81 DAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKVPTSRYMYAT 140
A+ E E +N DA+ F + V P+ IA +R + + +++A + T+ Y
Sbjct: 71 AAVTTEFENVNADAM-RFLAKHTNVSPSGDCVAIAQNRIQ-EKAWIRKAGLQTAPYQAIC 128
Query: 141 TLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAEKIIVEE 200
+++ E + A + GKG VK +++ A+ E + ++E+
Sbjct: 129 KAEDITEESIQFLPGILKTATLGYDGKGQIRVKTVDELKAAFAEHR------GVDCVLEK 182
Query: 201 HIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAEREVYRIA 260
+D EI+ + R ++N V TF P + +G S PA +S +++ ++A
Sbjct: 183 MVDLRGEISVIVCRLNNDN---VQTFD-PAENIHENGILAYSIVPARLSADIQQQARQMA 238
Query: 261 KRITDVLGGLGLFGVEMFVKGD--KVWANEVSPRPHDTGMVTLASHPPGFSEFGLHLRAV 318
+R+ D L +G+ VEMFV GD ++ NE++PRPH++G T+ + +F +R +
Sbjct: 239 QRLADELNYVGVLAVEMFVVGDTHELVVNEIAPRPHNSGHHTVDA--CAADQFQQQVRLM 296
Query: 319 LGLPIPGEWVDGYRLFPMLIPAATHVIKA-----------KVKGYSPRFRGLAKALSVPN 367
LP PA T ++ + + G P + L S P+
Sbjct: 297 CNLP----------------PADTKLLSSCCMANILGDVWQEDGGEPDWFPLQ---SRPD 337
Query: 368 ATVRLFGKPEAYVGRRLG--VVLAWDKDV--QEAKK 399
A + L+GK A+ GR++G +L+ D D QEAKK
Sbjct: 338 AHLHLYGKKTAHKGRKMGHFTILSTDSDTAFQEAKK 373
>emb|CAA04376.1| (AJ000883) purK [Lactococcus lactis]
Length = 349
Score = 104 bits (256), Expect = 3e-21
Identities = 87/313 (27%), Positives = 151/313 (47%), Gaps = 21/313 (6%)
Query: 14 DSAQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWS 73
++ Q I ++G G+LG+ +AI AQ +G +VI +D N A +V+ V D + L
Sbjct: 4 NTKQTIGIIGGGQLGQMMAIAAQYMGHKVITLDPNPNCSAAKVSDELIVAPYDDVENLLR 63
Query: 74 VVEREKPDAIIPEIEAINLDALFEFEKEGYFVVPNA-RATWIAMHRERLRETLVKEAKVP 132
+ D I E E ++ AL E EG +P R I +R +E L EAKV
Sbjct: 64 LA--YACDVITYEFENVSAKALHEI--EGCVRIPQGIRLLEITQNRRFEKEFLTNEAKVN 119
Query: 133 TSRYMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAKTKARGS 192
+ + +L ++ EK+ K ++ ++ G Y G + + + K+
Sbjct: 120 VAPW-------QLVDSAEKLPETVTRKQVLKTT-TGGYDGHGQVVLNTDEKLSAAKSLTE 171
Query: 193 AEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKA 252
+ ++E+ I F+ EI+ + NG FP ++ + H + PA IS +
Sbjct: 172 LSECVLEDFISFEREISVI----ISGNGHEYVVFPLAENEHR-ENILHQTISPARISAEI 226
Query: 253 EREVYRIAKRITDVLGGLGLFGVEMFVKGD-KVWANEVSPRPHDTGMVTLASHPPGFSEF 311
Y+IA I + L G+ VEMF+ D +++ NE++PRPH++G T+ + F++F
Sbjct: 227 TENAYKIATSIAEKLELSGVLCVEMFLTADGQIYVNELAPRPHNSGHFTIEA--CDFNQF 284
Query: 312 GLHLRAVLGLPIP 324
LH++ +LG +P
Sbjct: 285 DLHIKGILGEDLP 297
>sp|P12045|PURK_BACSU PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE ATPASE SUBUNIT (AIR
CARBOXYLASE) (AIRC) >gi|68000|pir||DCBSPK
phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)
carbon dioxide-fixation chain - Bacillus subtilis
>gi|143365|gb|AAA22675.1| (J02732) phosphoribosyl
aminoimidazole carboxylase II (PUR-K; ttg start codon)
[Bacillus subtilis] >gi|2632957|emb|CAB12463.1| (Z99107)
phosphoribosylaminoimidazole carboxylase II [Bacillus
subtilis]
Length = 379
Score = 102 bits (253), Expect = 6e-21
Identities = 87/307 (28%), Positives = 149/307 (48%), Gaps = 23/307 (7%)
Query: 21 LLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVEREKP 80
++G G+LGK +A+ A+++G +V VD ++P QVA + D++ + + E
Sbjct: 14 IIGGGQLGKMMAVSAKQMGYKVAVVDPVKDSPCGQVADVEITAHYNDREAIRKLAEIS-- 71
Query: 81 DAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKVPTSRYMYAT 140
D I E E I+ DAL + Y +P + + ++ A + Y
Sbjct: 72 DIITYEFENIDYDALHWLKDHAY--LPQGSELLLITQNRETEKKAIQSAGCEVAPYSIVK 129
Query: 141 TLDELYEACEKIGYPCHTKAIMSS-SGKGSYFVKGPEDIPKAWEEAKTKARGSAEKIIVE 199
T +EL +A +++ P K GKG + +K + +A A G+ I+E
Sbjct: 130 TKNELKQAVQELRLPAVLKTCRGGYDGKGQFVIKEEAQMEQA---AALLEHGTC---ILE 183
Query: 200 EHIDFDVEITELAVRHFDENGEIVTTFP--KPVGHYQIDGDYHASWQPAEISEKAEREVY 257
+ F +E++ + VR NGEI +TFP + + H I S PA + + +++
Sbjct: 184 SWVSFKMELSVIVVR--SVNGEI-STFPTAENIHHNNI---LFQSIVPA-VEKGIQQKAA 236
Query: 258 RIAKRITDVLGGLGLFGVEMFVKGD-KVWANEVSPRPHDTGMVTLASHPPGFSEFGLHLR 316
+A ++ D L +G VEMF+ D ++ NE++PRPH++G TL S+F H+R
Sbjct: 237 DLAVKLADELNLVGPLAVEMFLTEDGELLVNELAPRPHNSGHYTLDLCET--SQFEQHIR 294
Query: 317 AVLGLPI 323
AV GLP+
Sbjct: 295 AVCGLPL 301
>gb|AAK41328.1| Phosphoribosylaminoimidazole carboxylase ATPase subunit (purK)
[Sulfolobus solfataricus]
Length = 365
Score = 102 bits (252), Expect = 8e-21
Identities = 108/402 (26%), Positives = 179/402 (43%), Gaps = 56/402 (13%)
Query: 14 DSAQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWS 73
D KI +LG G+LG I +E ++ ++ NAPA ++A R + K+F+
Sbjct: 6 DWKPKIGILGGGQLGWMIVLEGRKYPFTFYVLENDKNAPACRIADRCFSPQDY-KEFV-- 62
Query: 74 VVEREKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLV-KEAKVP 132
+ D I E E + AL E G + R + + RER +E L ++ +P
Sbjct: 63 ----DSSDVITFEFEHVYEKALEYAEYSGKLL---PRLNSVELKRERYKEKLFYRQHNLP 115
Query: 133 TSRYMYATTLDE----LYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAKTK 188
T R+ A +E L E +G +K GKG YF+ + + E K
Sbjct: 116 TPRFYVAEDGEEALKILREEFNNVGVIKESKG--GYDGKGQYFIFNDVEKYQFLREKK-- 171
Query: 189 ARGSAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEI 248
EK++VEE++ FD E + + R D+ G ++ +P P +Y G ++ P
Sbjct: 172 -----EKMVVEEYVKFDFEASIIIAR--DKRGVFIS-YP-PTYNYNEKGILVYNYGPYN- 221
Query: 249 SEKAEREVYRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPPGF 308
+ + IA+R+++ L +G+ GVE+FV KV NE +PR H+TG TL
Sbjct: 222 ----NQNIVEIARRLSEELDYVGIMGVEVFVVNGKVLINEFAPRVHNTGHYTLDG--ALI 275
Query: 309 SEFGLHLRAVLGLPIPGEWVDGYRLFP--MLIPAATHVIKAKVKGYSPRFRGLAKALSVP 366
S+F HLRA++G+ + + L P M+ T I +V Y
Sbjct: 276 SQFEQHLRAIIGMELGPSTI----LSPSGMVNILGTDKIPVEVLKY-------------- 317
Query: 367 NATVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMI 408
V + K E R++G V +++E K++ + + +I
Sbjct: 318 -GKVYWYSKSEVRKRRKMGHVNVVGNNLEEVKQKIDKIMQLI 358
>sp|O06457|PURK_SULSO PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE ATPASE SUBUNIT (AIR
CARBOXYLASE) (AIRC) >gi|2104668|emb|CAA73603.1| (Y13143)
purK [Sulfolobus solfataricus]
Length = 365
Score = 102 bits (252), Expect = 8e-21
Identities = 108/402 (26%), Positives = 179/402 (43%), Gaps = 56/402 (13%)
Query: 14 DSAQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWS 73
D KI +LG G+LG I +E ++ ++ NAPA ++A R + K+F+
Sbjct: 6 DWKPKIGILGGGQLGWMIVLEGRKYPFTFYVLENDKNAPACRIADRCFSPQDY-KEFV-- 62
Query: 74 VVEREKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLV-KEAKVP 132
+ D I E E + AL E G + R + + RER +E L ++ +P
Sbjct: 63 ----DSSDVITFEFEHVYEKALEYAEYSGKLL---PRLNSVELKRERYKEKLFYRQHNLP 115
Query: 133 TSRYMYATTLDE----LYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAKTK 188
T R+ A +E L E +G +K GKG YF+ + + E K
Sbjct: 116 TPRFYVAEDGEEALKILREEFNNVGVIKESKG--GYDGKGQYFIFNDVEKYQFLREKK-- 171
Query: 189 ARGSAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEI 248
EK++VEE++ FD E + + R D+ G ++ +P P +Y G ++ P
Sbjct: 172 -----EKMVVEEYVKFDFEASIIIAR--DKRGVFIS-YP-PTYNYNEKGILVYNYGPYN- 221
Query: 249 SEKAEREVYRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPPGF 308
+ + IA+R+++ L +G+ GVE+FV KV NE +PR H+TG TL
Sbjct: 222 ----NQNIVEIARRLSEELDYVGIMGVEVFVVNGKVLINEFAPRVHNTGHYTLDG--ALI 275
Query: 309 SEFGLHLRAVLGLPIPGEWVDGYRLFP--MLIPAATHVIKAKVKGYSPRFRGLAKALSVP 366
S+F HLRA++G+ + + L P M+ T I +V Y
Sbjct: 276 SQFEQHLRAIIGMELGPSTI----LSPSGMVNILGTDKIPVEVLKY-------------- 317
Query: 367 NATVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMI 408
V + K E R++G V +++E K++ + + +I
Sbjct: 318 -GKVYWYSKSEVRKRRKMGHVNVVGNNLEEVKQKIDKIMQLI 358
>gi|6324702 phosphoribosylamino-imidazole-carboxylase; Ade2p [Saccharomyces
cerevisiae] >gi|131630|sp|P21264|PUR6_YEAST
PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (AIR
CARBOXYLASE) (AIRC) >gi|68002|pir||DEBYP
phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) -
yeast (Saccharomyces cerevisiae)
>gi|171003|gb|AAA34401.1| (M59824) phosphoribosyl
aminoimidazole carboxylase [Saccharomyces cerevisiae]
>gi|1050830|emb|CAA62125.1| (X90518) ORF O3293
[Saccharomyces cerevisiae] >gi|1164972|emb|CAA64047.1|
(X94335) YOR3293c [Saccharomyces cerevisiae]
>gi|1420332|emb|CAA99327.1| (Z75036) ORF YOR128c
[Saccharomyces cerevisiae] >gi|3243009|gb|AAC23867.1|
(AF069717) phosphoribosylaminoimidazole carboxylase
[Expression vector pBEVY-A] >gi|3243012|gb|AAC23869.1|
(AF069718) phosphoribosylaminoimidazole carboxylase
[Expression vector pBEVY-GA] >gi|3243116|gb|AAC40224.1|
(AF039102) phosphoribosylamino-imidazole-carboxylase
[Integrating expression vector YIpDCE1]
Length = 571
Score = 100 bits (247), Expect = 3e-20
Identities = 100/404 (24%), Positives = 184/404 (44%), Gaps = 30/404 (7%)
Query: 21 LLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVEREKP 80
+LG G+LG+ I A RL ++ + +D N+PA Q+++ + N + L EK
Sbjct: 8 ILGGGQLGRMIVEAANRLNIKTVILDA-ENSPAKQISNSNDHVNGSFSNPLDIEKLAEKC 66
Query: 81 DAIIPEIEAINLDAL--FEFEKEGYFVVPNARATWIAMHRERLRETLVKEA-KVPTSRYM 137
D + EIE +++ L + + + P+ + + +E L+K V S +
Sbjct: 67 DVLTIEIEHVDVPTLKNLQVKHPKLKIYPSPETIRLIQDKYIQKEHLIKNGIAVTQSVPV 126
Query: 138 YATTLDELYEACEKIGYPCHTKA-IMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAEKI 196
+ L +G+P K+ ++ G+G++ VK E IP+A E K + +
Sbjct: 127 EQASETSLLNVGRDLGFPFVLKSRTLAYDGRGNFVVKNKEMIPEALEVLKDRP------L 180
Query: 197 IVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAEREV 256
E+ F E+ + VR NG +V ++P V D + PA + + + +
Sbjct: 181 YAEKWAPFTKELAVMIVRSV--NG-LVFSYPI-VETIHKDNICDLCYAPARVPDSVQLKA 236
Query: 257 YRIAKRITDVLGGLGLFGVEMF-VKGDKVWANEVSPRPHDTGMVTLASHPPGFSEFGLHL 315
+A+ G G+FGVEMF ++ ++ NE++PRPH++G T+ + S+F HL
Sbjct: 237 KLLAENAIKSFPGCGIFGVEMFYLETGELLINEIAPRPHNSGHYTIDACVT--SQFEAHL 294
Query: 316 RAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKG----YSPRFRGLAKALSVPNATVR 371
R++L LP+P + F T+ I V G +AL+ P ++V
Sbjct: 295 RSILDLPMP-------KNFTSFSTITTNAIMLNVLGDKHTKDKELETCERALATPGSSVY 347
Query: 372 LFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIELRTRSS 415
L+GK E+ R++G + + E ++R + ++ + S
Sbjct: 348 LYGK-ESRPNRKVGHINIIASSMAECEQRLNYITGRTDIPIKIS 390
>emb|CAB44982.1| (AJ242842) putative phosphoribosylaminoimidazole carboxylase
[Neisseria meningitidis]
Length = 378
Score = 100 bits (246), Expect = 4e-20
Identities = 105/396 (26%), Positives = 181/396 (45%), Gaps = 53/396 (13%)
Query: 21 LLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVEREKP 80
+LG G+LG+ + A+ +G +V +D +APA + A D+ L E K
Sbjct: 14 ILGGGQLGRMFTVAAKTMGYKVTVLDPDPDAPAAEFADCHLCAPFNDQAAL---DELAKC 70
Query: 81 DAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKVPTSRYMYAT 140
A+ E E +N DA+ F + V P + IA +R + + +++A + T+ Y
Sbjct: 71 AAVTTEFENVNADAM-RFLAKHTNVSPGSDCVAIAQNRIQ-EKAWIRKAGLQTAPYQAIC 128
Query: 141 TLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAEKIIVEE 200
+++ E + A + GKG VK +++ A+ E + ++E+
Sbjct: 129 KAEDITEESIQFLPGILKTATLGYDGKGQIRVKTVDELKAAFAEHR------GVDCVLEK 182
Query: 201 HIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAEREVYRIA 260
+D EI+ + R ++N V TF P + +G S PA +S +++ ++A
Sbjct: 183 MVDLRGEISVIVCRLNNDN---VQTFD-PAENIHENGILAYSIVPARLSADIQQQARQMA 238
Query: 261 KRITDVLGGLGLFGVEMFVKGD--KVWANEVSPRPHDTGMVTLASHPPGFSEFGLHLRAV 318
+R+ D L +G+ VEMFV GD ++ NE++PRPH++G T+ + +F +R +
Sbjct: 239 QRLADELNYVGVLAVEMFVVGDTHELVVNEIAPRPHNSGHHTVDA--CAADQFQQQVRLM 296
Query: 319 LGLPIPGEWVDGYRLFPMLIPAATHVIKA-----------KVKGYSPRFRGLAKALSVPN 367
LP PA T ++ + + G P + L S P+
Sbjct: 297 CNLP----------------PADTKLLSSCCMANILGDVWQEDGGEPDWFPLQ---SRPD 337
Query: 368 ATVRLFGKPEAYVGRRLG--VVLAWDKDV--QEAKK 399
A + L+GK A+ GR++G VL D D QEAKK
Sbjct: 338 AHLHLYGKKTAHKGRKMGHFTVLTTDSDTAFQEAKK 373
>sp|Q54975|PURK_SYNP7 PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE ATPASE SUBUNIT (AIR
CARBOXYLASE) (AIRC) >gi|1470119|gb|AAB05791.1| (U62615)
phosphoribosyl aminoimidazole carboxylase [Synechococcus
PCC7942] >gi|445630|prf||1909376A rbc downstream ORF 1
[Synechococcus sp.]
Length = 395
Score = 100 bits (246), Expect = 4e-20
Identities = 96/397 (24%), Positives = 182/397 (45%), Gaps = 30/397 (7%)
Query: 17 QKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVE 76
Q + ++G G+L +A AQ+LG+ + + PA+ +A ++ + + D + +
Sbjct: 10 QHVGVIGGGQLAWMLAPAAQQLGMSLHVQTPNDHDPAVAIADQTVLAAVRDAAATAKLAQ 69
Query: 77 REKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKVPTSRY 136
D I E E ++L AL E E+ G P A + + R+ L + +PT R+
Sbjct: 70 A--CDVITFENEFVDLPALTELEETGVRFRPRPAAIASLLDKLDQRQLLTRLG-LPTPRF 126
Query: 137 MYATTLDELYEACEKIGYPCHTKAIMSS-SGKGSYFVKGPEDIPKAWEEAKTKARGSAEK 195
+ +G+P K GKG+ ++ ++ +A +
Sbjct: 127 LAIAAATATESELTALGFPVVLKQRRHGYDGKGTQVLRSLAELQQALQSY------GDTP 180
Query: 196 IIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASW--QPAEISEKAE 253
+++EE I F+ E+ + R ++G I T FP H Q + W PA I +
Sbjct: 181 LLLEEFIPFEQELAVMVAR--SQSGAIAT-FPVVQTHQQ---NQVCRWVVAPAAIPGALQ 234
Query: 254 REVYRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPPGFSEFGL 313
+ V IA+ + + + +G+ G+E+F +GD++W NE++PR H++G +L + S+F
Sbjct: 235 KAVAAIARTLVETVDYVGVAGIELFQQGDRLWVNEIAPRTHNSGHYSLDACQT--SQFEQ 292
Query: 314 HLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLAKALSVPNATVRLF 373
LRA+ LP+ + +P + + GY+ + LA ++P A + +
Sbjct: 293 QLRAIADLPLGSTALQ----WPGALMVNLLGFEDHQSGYAELRQQLA---ALPGACLYWY 345
Query: 374 GKPEAYVGRRLGVV---LAWDKDVQEAKKRAEMVAHM 407
GK E+ GR+LG + L+ + A++ M+A +
Sbjct: 346 GKTESKPGRKLGHITLPLSGASSTERAQQAQTMLAQV 382
>sp|O66608|PURK_AQUAE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE ATPASE SUBUNIT (AIR
CARBOXYLASE) (AIRC) >gi|7436523|pir||D70322 probable
phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)
carbon dioxide-fixation chain purK [similarity] -
Aquifex aeolicus >gi|2982952|gb|AAC06567.1| (AE000680)
phosphoribosyl aminoimidazole carboxylase [Aquifex
aeolicus]
Length = 365
Score = 96.0 bits (235), Expect = 8e-19
Identities = 106/392 (27%), Positives = 184/392 (46%), Gaps = 44/392 (11%)
Query: 21 LLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVEREKP 80
+LG G+LG +E ++LG + ++ NAPA +VA R + + +F+ +
Sbjct: 6 ILGGGQLGWMTILEGRKLGFKFHVLEDKENAPACRVADRCFRTGQI-SEFV------DSC 58
Query: 81 DAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETL-VKEAKVPTSRYMYA 139
D I E E I + L + E + ++PN +A ++ + R+RE L +K+ P ++
Sbjct: 59 DIITYEFEHIKDEVLEKCESK---LIPNPQALYV--KKSRIREKLFLKKHGFPVPEFL-V 112
Query: 140 TTLDELYEACEKIGYPCHTKA-IMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAEKIIV 198
DE+ +A + P KA + GKG Y +K ED + K E I+
Sbjct: 113 IKRDEIIDALKSFKLPVVIKAEKLGYDGKGQYRIKKLEDANQV-----VKNHDKEESFII 167
Query: 199 EEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAEREVYR 258
EE + F+ EI+ + VR D G+ +P+P ++ +G ++ P ++AE
Sbjct: 168 EEFVKFEAEISCIGVR--DREGK-TYFYPQPFNKHE-EGILIYNYVPYAKLKEAE----E 219
Query: 259 IAKRITDVLGGLGLFGVEMF-VKGDKVWANEVSPRPHDTGMVTLASHPPGFSEFGLHLRA 317
I KR+ ++L +G+F VE F +K +V NE +PR H+TG TL S+F LRA
Sbjct: 220 ITKRLMELLDIVGVFTVEFFLLKDGRVLINEFAPRVHNTGHWTLDG--AYTSQFENLLRA 277
Query: 318 VLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLAKALSVPNATVRLFGKPE 377
+ +P+ + +P+ + G S L + LSV A + +GK E
Sbjct: 278 ITEMPLGST--------ELKLPSG----MVNILGKSYEEIPLKEILSVEGAKLYWYGK-E 324
Query: 378 AYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIE 409
R++G V + +E ++ E V +++
Sbjct: 325 KKPRRKVGHVNVVGRSKEEVVEKVERVFTLLK 356
>pir||B82528 phosphoribosylaminoimidazole carboxylase, ATPase subunit XF2671
[imported] - Xylella fastidiosa (strain 9a5c)
>gi|9107907|gb|AAF85468.1|AE004073_3 (AE004073)
phosphoribosylaminoimidazole carboxylase, ATPase subunit
[Xylella fastidiosa]
Length = 393
Score = 96.0 bits (235), Expect = 8e-19
Identities = 92/313 (29%), Positives = 148/313 (46%), Gaps = 16/313 (5%)
Query: 21 LLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVEREKP 80
+LG G+L + +A+ A LGV V D+ +A A Q+ +VG D L V R
Sbjct: 6 ILGGGQLARMLALAAPPLGVRVCTFDQTVDACAGQMTPL-WVGCFDDVAALRDFVARV-- 62
Query: 81 DAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRE-TLVKEAKVPTSRYMYA 139
D I + E + + A + KE V PN +A+ ++RL E TL ++ +P ++
Sbjct: 63 DVITFDSENLPV-ASVQVLKEHVPVYPNPEV--LAVAQDRLSEKTLFRDLGIPVPDFVAV 119
Query: 140 TTLDELYEACEKIGYPCHTKAI-MSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAEKIIV 198
L A K+G PC K GKG + +K D AW A + +I+
Sbjct: 120 DNRAALDVAIVKVGTPCILKTRRFGYDGKGQFRIKTLIDADAAW--AMLGEQAGITGLIL 177
Query: 199 EEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAEREVYR 258
E + F E++ LAVR NG+ ++P ++ + G S P + +
Sbjct: 178 EAFVPFQREMSILAVRGC--NGQF-RSWPL-TENWHVAGVLSVSLAPMAVDPTLQAAAEA 233
Query: 259 IAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPPGFSEFGLHLRAV 318
A+ + + L +G+F +E+FV ++ ANE++PR H++G T+ S+F HLRAV
Sbjct: 234 YARVLAERLDYVGVFALELFVHDGRLLANEMAPRVHNSGHWTIEGAET--SQFENHLRAV 291
Query: 319 LGLPIPGEWVDGY 331
GLP+ + GY
Sbjct: 292 FGLPLGSTAMRGY 304
>sp|P55195|PUR6_VIGAC PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE PRECURSOR (AIR
CARBOXYLASE) (AIRC) >gi|629656|pir||S43322
phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) -
moth bean >gi|349159|gb|AAC37400.1| (L22584)
5-aminoimidazole ribonucleotide carboxylase [Vigna
aconitifolia]
Length = 557
Score = 94.0 bits (230), Expect = 3e-18
Identities = 89/366 (24%), Positives = 161/366 (43%), Gaps = 22/366 (6%)
Query: 21 LLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVEREKP 80
+LG G+LG+ + A ++ ++V+ +D N PA +++ VG+ + + +R
Sbjct: 9 VLGGGQLGRMMCQAASQMAIKVMVLDPQENCPASSLSYHHMVGSFDESTKVEEFAKR--C 66
Query: 81 DAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKVPTSRYMYAT 140
+ EIE +++D L + EK+G P A I + + + L+ A +P +M
Sbjct: 67 GVLTVEIEHVDVDTLEKLEKQGVDCQPKASTVRIIQDKYQQKVALL-PAWIPLPEFMKID 125
Query: 141 TLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAEKIIVEE 200
L I + ++ ++ G+G++ K E++ A + RG + E+
Sbjct: 126 DLKAKKWDSLDIHFMIKSRR-LAYDGRGNFVAKSEEELSSAVDALGGFDRG----LYAEK 180
Query: 201 HIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAEREVYRIA 260
F E+ + R D + GH H PA ++ K +A
Sbjct: 181 WAPFVKELAVIVARGRDNSISCYPVVELFTGHI-----CHIVKSPANVNWKTRELAIEVA 235
Query: 261 KRITDVLGGLGLFGVEMFV-KGDKVWANEVSPRPHDTGMVTLAS-HPPGFSEFGLHLRAV 318
L G+F VE+F+ K ++ NEV+PRPH++G T+ S H S+F HL AV
Sbjct: 236 FNAVKSLEVPGVFAVELFLTKEGEILLNEVAPRPHNSGHHTIESCHT---SQFEQHLPAV 292
Query: 319 LGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLAKALSVPNATVRLFGKPEA 378
+GLP+ D P I + G+ + + +A+++P A+V + KPE
Sbjct: 293 VGLPLG----DPSMKTPAAIMYNILGEEEGEHGFQLAHQLMKRAMTIPGASVHWYDKPEM 348
Query: 379 YVGRRL 384
R++
Sbjct: 349 RKQRKM 354
>gb|AAG19135.1| (AE005011) phosphoribosylaminoimidazole carboxylase ATP binding
subunit; PurK [Halobacterium sp. NRC-1]
Length = 364
Score = 93.6 bits (229), Expect = 4e-18
Identities = 79/293 (26%), Positives = 130/293 (43%), Gaps = 15/293 (5%)
Query: 31 IAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVEREKPDAIIPEIEAI 90
+A A LGV+VI +D + PA Q A + D D + + R D + EIE
Sbjct: 2 LADAASPLGVDVIVLDPTPDCPASQPATDHIRADFDDPDGVRELAARA--DVLTYEIELA 59
Query: 91 NLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKVPTSRYMYATTLDELYEACE 150
+ D L + + V + T + + ++ + +A +P + +L A E
Sbjct: 60 DPDVLADAAEAHEVAVHPSPETLRTIQDKLVQNRALADAGIPVPAFRAVDDAADLRAAFE 119
Query: 151 KIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAEKIIVEEHIDFDVEITE 210
++G P +M G Y G + +A+ + G + EE +DF+ E++
Sbjct: 120 ELGAP-----LMLKRRTGGYDGSGNAPVDSV-ADARAEFGGDLGGFVAEELVDFERELSV 173
Query: 211 LAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAEREVYRIAKRITDVLGGL 270
+A R E TFP ++ + S PA S + +A + D L G
Sbjct: 174 IAARGDAETA----TFPVAENLHEAE-ILRESVVPARTSPAVREDATGVAADVLDALDGR 228
Query: 271 GLFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPPGFSEFGLHLRAVLGLPI 323
G+FGVE+F +V NE++PRPH++G T+ S+F +RAVLGLP+
Sbjct: 229 GVFGVELFAVDGRVLVNEIAPRPHNSGHYTIEGCRT--SQFEQCIRAVLGLPL 279
>gb|AAC98316.1| (AF112302) phosphoribosylaminoimidazole carboxylase [Filobasidiella
neoformans]
Length = 582
Score = 93.2 bits (228), Expect = 5e-18
Identities = 106/413 (25%), Positives = 179/413 (42%), Gaps = 39/413 (9%)
Query: 21 LLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVEREKP 80
+LG G+LG+ + A LG+ ++ +D + PA Q + D F R+
Sbjct: 9 ILGGGQLGRMLTHPAALLGIPLLILDSGSYTPAKQTLLPPPPHSHPDGPFTSETHIRKLA 68
Query: 81 ---DAIIPEIEAINLDALFEFEKEGYFVV-PNARATWIAMHRERLRETLVKE--AKVPTS 134
D + EIE +N D L EKEG V P+ + + ++ ++ L + A P
Sbjct: 69 SACDILTVEIEHVNADVLEAVEKEGLCEVQPSPKTIRLIQNKYDQKKYLAERGVAVAPFE 128
Query: 135 RYMYATTLDELYEACEKIGYPCHTKA-IMSSSGKGSYFVKGP--EDIPKAWEEAKTKARG 191
T ++ ++G P KA ++ G+G+ +K EDI +A K G
Sbjct: 129 ELPANPTEEDFKAIAGRLGLPLMLKAKTLAYDGRGNSPLKSASSEDI-----QASLKFLG 183
Query: 192 SAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEK 251
+ E F E+ + VR+ + GE+ + H + P +
Sbjct: 184 D-RPLYAEGWAPFVKEVAVMVVRN--KEGEVQSYDAVETIHRE--SILRVCLTPLRGEKG 238
Query: 252 AEREVYRIAKRITDVLGGLGLFGVEMFVKGD-KVWANEVSPRPHDTGMVTLASHPPGFSE 310
+ +A++ L G G+FGVEMF+ D ++ NE++PRPH++G T+ + S+
Sbjct: 239 VNQRARELAEKAVGHLEGAGIFGVEMFLMPDGELLLNEIAPRPHNSGHHTIEACLT--SQ 296
Query: 311 FGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLAK----ALSVP 366
F HLRA+L LP+ + +P+A V + G S + K AL+VP
Sbjct: 297 FENHLRAILSLPLGST--------ALRVPSAAMV---NILGASSTMDAIDKMADNALTVP 345
Query: 367 NATVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIELRTRSSDWHD 419
A V L+GK E+ R++G + + E +R + A + +DW D
Sbjct: 346 GAAVHLYGKAESRKARKMGHITVTAESDAELNER--LRALLFAQPDAHADWID 396
>emb|CAC12234.1| (AL445066) phosphoribosylaminoimidazole carboxylase related protein
[Thermoplasma acidophilum]
Length = 360
Score = 93.2 bits (228), Expect = 5e-18
Identities = 79/304 (25%), Positives = 134/304 (43%), Gaps = 31/304 (10%)
Query: 21 LLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVEREKP 80
++G+G+LG + E +RLG + +D PA +A + K ++
Sbjct: 7 IIGTGQLGFMMINEGRRLGNRYLVLDSNGVGPASLIADAHFSPEEYRKFV-------DQS 59
Query: 81 DAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKVPTSRYMYAT 140
D + E E + +AL + +G + P ++ + R + ++ L +P + Y A+
Sbjct: 60 DVVTFEFEHVMEEALEYAQSQGK-LFPGIQSVELKKDRSKEKDFLTDNG-LPVAEYHVAS 117
Query: 141 TLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAEKIIVEE 200
+ DE +G A GKG G R ++ +VEE
Sbjct: 118 SFDEAVRYARDMGKAVIKNAYGGYDGKGQIVYDGG-----------VSERLQGDRFVVEE 166
Query: 201 HIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAEREVYRIA 260
IDFD E + +AVR D N T+ P +Y + + + P + E + IA
Sbjct: 167 FIDFDYEASIIAVRDRDGN----FTYFDPTYNYNREAIFIYNVAPTD-----ELTMPAIA 217
Query: 261 KRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPPGFSEFGLHLRAVLG 320
K++ + L G+ G+E +V+ KV NE +PR H++G TL S+F H+RA+ G
Sbjct: 218 KKLMEALDYHGVMGIEFYVRKRKVIINEYAPRVHNSGHHTLLG--SSVSQFEEHVRAISG 275
Query: 321 LPIP 324
LP+P
Sbjct: 276 LPVP 279
>gb|AAB09711.1| (U70673) phosphoribosylaminoimidazole carboxylase [Filobasidiella
neoformans]
Length = 583
Score = 92.1 bits (225), Expect = 1e-17
Identities = 104/415 (25%), Positives = 179/415 (43%), Gaps = 43/415 (10%)
Query: 21 LLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQV-----AHRSYVGNMMDKDFLWSVV 75
+LG G+LG+ + A LG+ ++ +D + PA Q +H G + + +
Sbjct: 10 ILGGGQLGRMLTHPAALLGIPLLILDSGSFTPAKQTLLPPPSHSHPDGPFTSEPHIRKLA 69
Query: 76 EREKPDAIIPEIEAINLDALFEFEKEGYFVV-PNARATWIAMHRERLRETLVKE--AKVP 132
D + EIE +N D L EKEG V P+ + + ++ ++ L ++ A P
Sbjct: 70 SA--CDILTVEIEHVNADVLEAVEKEGLCEVQPSPKTIRLIQNKYDQKKYLAEKGVAVAP 127
Query: 133 TSRYMYATTLDELYEACEKIGYPCHTKA-IMSSSGKGSYFVKGP--EDIPKAWEEAKTKA 189
T ++ ++G P KA ++ G+G+ +K EDI +A K
Sbjct: 128 FEELPANPTEEDFKAIAGRLGLPLMLKAKTLAYDGRGNSPLKSTSSEDI-----QASLKF 182
Query: 190 RGSAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEIS 249
G + E F E+ + VR+ + GE+ + H + P
Sbjct: 183 LGD-RPLYAEGWAPFVKEVAVMVVRN--KEGEVQSYDAVETIHRE--SILRVCLAPLRGE 237
Query: 250 EKAEREVYRIAKRITDVLGGLGLFGVEMFVKGD-KVWANEVSPRPHDTGMVTLASHPPGF 308
+ +A++ L G G+FGVEMF+ D ++ NE++PRPH++G T+ +
Sbjct: 238 RGVNQRARELAEKAVGHLEGAGIFGVEMFLMPDGELLLNEIAPRPHNSGHHTIEACLT-- 295
Query: 309 SEFGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLAK----ALS 364
S+F HLRA+L LP+ + +P+A V + G S + K AL+
Sbjct: 296 SQFENHLRAILSLPLGST--------ALRVPSAAMV---NILGASSTMDAIDKMADNALT 344
Query: 365 VPNATVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIELRTRSSDWHD 419
VP A V L+GK E+ R++G + + E +R + + +DW D
Sbjct: 345 VPGAAVHLYGKAESRKARKMGHITVTAESDAELNERLRTL--LFAQPDAHADWID 397
>sp|Q92233|PUR6_CRYNE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (AIR CARBOXYLASE) (AIRC)
Length = 582
Score = 92.1 bits (225), Expect = 1e-17
Identities = 104/415 (25%), Positives = 179/415 (43%), Gaps = 43/415 (10%)
Query: 21 LLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQV-----AHRSYVGNMMDKDFLWSVV 75
+LG G+LG+ + A LG+ ++ +D + PA Q +H G + + +
Sbjct: 9 ILGGGQLGRMLTHPAALLGIPLLILDSGSFTPAKQTLLPPPSHSHPDGPFTSEPHIRKLA 68
Query: 76 EREKPDAIIPEIEAINLDALFEFEKEGYFVV-PNARATWIAMHRERLRETLVKE--AKVP 132
D + EIE +N D L EKEG V P+ + + ++ ++ L ++ A P
Sbjct: 69 SA--CDILTVEIEHVNADVLEAVEKEGLCEVQPSPKTIRLIQNKYDQKKYLAEKGVAVAP 126
Query: 133 TSRYMYATTLDELYEACEKIGYPCHTKA-IMSSSGKGSYFVKGP--EDIPKAWEEAKTKA 189
T ++ ++G P KA ++ G+G+ +K EDI +A K
Sbjct: 127 FEELPANPTEEDFKAIAGRLGLPLMLKAKTLAYDGRGNSPLKSTSSEDI-----QASLKF 181
Query: 190 RGSAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEIS 249
G + E F E+ + VR+ + GE+ + H + P
Sbjct: 182 LGD-RPLYAEGWAPFVKEVAVMVVRN--KEGEVQSYDAVETIHRE--SILRVCLAPLRGE 236
Query: 250 EKAEREVYRIAKRITDVLGGLGLFGVEMFVKGD-KVWANEVSPRPHDTGMVTLASHPPGF 308
+ +A++ L G G+FGVEMF+ D ++ NE++PRPH++G T+ +
Sbjct: 237 RGVNQRARELAEKAVGHLEGAGIFGVEMFLMPDGELLLNEIAPRPHNSGHHTIEACLT-- 294
Query: 309 SEFGLHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLAK----ALS 364
S+F HLRA+L LP+ + +P+A V + G S + K AL+
Sbjct: 295 SQFENHLRAILSLPLGST--------ALRVPSAAMV---NILGASSTMDAIDKMADNALT 343
Query: 365 VPNATVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIELRTRSSDWHD 419
VP A V L+GK E+ R++G + + E +R + + +DW D
Sbjct: 344 VPGAAVHLYGKAESRKARKMGHITVTAESDAELNERLRTL--LFAQPDAHADWID 396
>pir||B82370 phosphoribosylaminoimidazole carboxylase, ATPase chain VC0051
[imported] - Vibrio cholerae (group O1 strain N16961)
>gi|9654445|gb|AAF93229.1| (AE004096)
phosphoribosylaminoimidazole carboxylase, ATPase subunit
[Vibrio cholerae]
Length = 377
Score = 90.5 bits (221), Expect = 3e-17
Identities = 81/312 (25%), Positives = 145/312 (45%), Gaps = 28/312 (8%)
Query: 18 KILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVER 77
++L+LG+G+L + +++ L +E IA D + + ++ +G+ +++
Sbjct: 2 RVLVLGAGQLARMMSLAGAPLNIETIAFD-VGSENIVHPLTQTVLGHGLEQAI------- 53
Query: 78 EKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKVPTSRYM 137
E+ D I E E I L + G + P+A A R RL + L+ A+V +RY
Sbjct: 54 EQVDVITAEFEHIPHPILDLCARSGK-LYPSAEAIKAGGDR-RLEKALLDRAQVANARYT 111
Query: 138 YATTLDELYEACEKIGYPCHTKAIMSS-SGKGSYFVKGPEDIPKAWEE-AKTKARGSAEK 195
+ D+L A +IG P K+ + GKG + +K P I W+E A+ A +
Sbjct: 112 MIRSRDDLTSAIAEIGLPMVLKSALGGYDGKGQWRLKEPTQIESVWQELAQYLAANPEQA 171
Query: 196 IIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHA----SWQPAEISEK 251
I+ EE + FD E++ + R+ G++V Y + + H S A +
Sbjct: 172 IVAEEFVAFDREVSLVGARNLV--GDVVV--------YPLAENVHTQGVLSLSTAIDAPA 221
Query: 252 AEREVYRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPPGFSEF 311
+ + + K + + L +G+ +E F ++ NE++PR H++G T +F
Sbjct: 222 LQTQAKAMFKAVAEQLNYVGVLALEFFEVQGQLLVNEIAPRVHNSGHWT--QQGAETCQF 279
Query: 312 GLHLRAVLGLPI 323
HLRAV GLP+
Sbjct: 280 ENHLRAVCGLPL 291
>gb|AAA34407.1| (M58324) phosphoribosylaminoimidazole carboxylase [Saccharomyces
cerevisiae]
Length = 570
Score = 89.7 bits (219), Expect = 6e-17
Identities = 98/404 (24%), Positives = 180/404 (44%), Gaps = 31/404 (7%)
Query: 21 LLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVEREKP 80
+LG G+LG+ I A RL ++ + +D N+PA Q+++ + N + L EK
Sbjct: 8 ILGGGQLGRMIVEAANRLNIKTVILDA-ENSPAKQISNSNDHVNGSFSNPLDIEKLAEKC 66
Query: 81 DAIIPEIEAINLDAL--FEFEKEGYFVVPNARATWIAMHRERLRETLVKEA-KVPTSRYM 137
D + EIE +++ L + + + P+ + + +E L+K V S +
Sbjct: 67 DVLTIEIEHVDVPTLKNLQVKHPKLKIYPSPETIGLIQDKYIQKEHLIKNGIAVTQSVPV 126
Query: 138 YATTLDELYEACEKIGYPCHTKA-IMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAEKI 196
+ L +G+P K+ ++ G+G++ VK E IP+A E K + +
Sbjct: 127 EQASETSLLNVGRDLGFPFVLKSRTLAYDGRGNFVVKNKEMIPEALEVLKDR------PL 180
Query: 197 IVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAEREV 256
E+ F E+ + VR NG + F V D + PA + + + +
Sbjct: 181 YAEKWGPFTKELAVMIVR--SVNG--LVFFYPIVETIHKDNICDLCYAPARVPDSVQLKA 236
Query: 257 YRIAKRITDVLGGLGLFGVEMF-VKGDKVWANEVSPRPHDTGMVTLASHPPGFSEFGLHL 315
+AK ++ L GVEMF ++ ++ NE++PRPH++G T+ + S+F HL
Sbjct: 237 KLLAKMQSN-FSRLWYIGVEMFYLETGELLINEIAPRPHNSGHYTIDACVT--SQFEAHL 293
Query: 316 RAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKG----YSPRFRGLAKALSVPNATVR 371
R++L LP+P + F T+ I V G +AL+ P ++V
Sbjct: 294 RSILDLPMP-------KNFTSFSTITTNAIMLNVLGDKHTKDKELETCERALATPGSSVY 346
Query: 372 LFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIELRTRSS 415
L+GK E+ R++G + + E ++R + ++ + S
Sbjct: 347 LYGK-ESRPNRKVGHINIIASSMAECEQRLNYITGRTDIPLKIS 389
>dbj|BAA22049.1| (AB006759) subunit II of phosphoribosyl aminoimidazole carboxylase
[Synechococcus sp.]
Length = 334
Score = 88.5 bits (216), Expect = 1e-16
Identities = 83/333 (24%), Positives = 152/333 (44%), Gaps = 28/333 (8%)
Query: 81 DAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKVPTSRYMYAT 140
D I E E ++L AL E E+ G P A + + R+ L + +PT R++
Sbjct: 11 DVITFENEFVDLPALTELEETGVRFRPRPAAIASLLDKLDQRQLLTRLG-LPTPRFLAIA 69
Query: 141 TLDELYEACEKIGYPCHTKAIMSS-SGKGSYFVKGPEDIPKAWEEAKTKARGSAEKIIVE 199
+G+P K GKG+ ++ ++ +A + +++E
Sbjct: 70 AATATESELTALGFPVVLKQRRHGYDGKGTQVLRSLAELQQALQSY------GDTPLLLE 123
Query: 200 EHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASW--QPAEISEKAEREVY 257
E I F+ E+ + R ++G I T FP H Q + W PA I ++ V
Sbjct: 124 EFIPFEQELAVMVAR--SQSGAIAT-FPVVQTHQQ---NQVCRWVVAPAAIPGALQKAVA 177
Query: 258 RIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPPGFSEFGLHLRA 317
IA+ + + + +G+ G+E+F +GD++W NE++PR H++G +L + S+F LRA
Sbjct: 178 AIARTLVETVDYVGVAGIELFQQGDRLWVNEIAPRTHNSGHYSLDACQT--SQFEQQLRA 235
Query: 318 VLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLAKALSVPNATVRLFGKPE 377
+ LP+ + +P + + GY+ + LA ++P A + +GK E
Sbjct: 236 IADLPLGSTALQ----WPGALMVNLLGFEDHQSGYAELRQQLA---ALPGACLYWYGKTE 288
Query: 378 AYVGRRLGVV---LAWDKDVQEAKKRAEMVAHM 407
+ GR+LG + L+ + A++ M+A +
Sbjct: 289 SKPGRKLGHITLPLSGASSTERAQQAQTMLAQV 321
>sp|P96881|PURK_MYCTU PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE ATPASE SUBUNIT (AIR
CARBOXYLASE) (AIRC) >gi|7478841|pir||E70979 carbon
dioxide-fixation chain purK [similarity] - Mycobacterium
tuberculosis (strain H37RV) >gi|1877331|emb|CAB07079.1|
(Z92771) purK [Mycobacterium tuberculosis]
Length = 429
Score = 86.2 bits (210), Expect = 6e-16
Identities = 106/410 (25%), Positives = 175/410 (41%), Gaps = 24/410 (5%)
Query: 12 TTDSAQKILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFL 71
T+ A + ++G G+L + A LG + + A+ PA QV +G+ D L
Sbjct: 13 TSFIAPLVAMVGGGQLARMTHQAAIALGQNLRVLVTSADDPAAQVTPNVVIGSHTDLAAL 72
Query: 72 WSVVEREKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKV 131
V D + + E + + L + +G V P+ +A A + +R+ L A V
Sbjct: 73 RRVAAGA--DVLTFDHEHVPNELLEKLVADGVNVAPSPQALVHAQDKLVMRQRLAA-AGV 129
Query: 132 PTSRYMYATTLDELYEACEKIGYPCHTKAIMSS-SGKGSYFVKGPEDIPKAWEEAKTKAR 190
RY DE+ ++ P KA+ G+G V+ D+ A + A+ +
Sbjct: 130 AVPRYAGIKDPDEIDVFAARVDAPIVVKAVRGGYDGRG---VRMARDVADARDFAR-ECL 185
Query: 191 GSAEKIIVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAE-IS 249
++VEE +D E++ L R G +P V Q DG PA +
Sbjct: 186 ADGVAVLVEERVDLRRELSALVARSPFGQG---AAWPV-VQTVQRDGTCVLVIAPAPALP 241
Query: 250 EKAEREVYRIAKRITDVLGGLGLFGVEMFVKGD-KVWANEVSPRPHDTGMVTLASHPPGF 308
+ R+A ++ D LG +G+ VE+F D + NE++ RPH++G T+
Sbjct: 242 DDLATAAQRLALQLADELGVVGVLAVELFETTDGALLVNELAMRPHNSGHWTIDGART-- 299
Query: 309 SEFGLHLRAVLGLPIPGEWVDGYRLFPMLIPA-ATHVIKAKVKGYSPRFRGLAKALSVPN 367
S+F HLRAVL P+ D + P+ + A + R L + P+
Sbjct: 300 SQFEQHLRAVLDYPLG----DSDAVVPVTVMANVLGAAQPPAMSVDERLHHLFARM--PD 353
Query: 368 ATVRLFGKPEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMIELRTRSSDW 417
A V L+GK E GR++G + DV + +RAE+ AH + + W
Sbjct: 354 ARVHLYGKAER-PGRKVGHINFLGSDVAQLCERAELAAHWLSHGRWTDGW 402
>pir||A75569 probable phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)
carbon dioxide-fixation chain DR0024 [similarity] -
Deinococcus radiodurans (strain R1)
>gi|6457683|gb|AAF09616.1|AE001866_3 (AE001866)
phosphoribosylaminoimidazole carboxylase, ATPase subunit
[Deinococcus radiodurans]
Length = 370
Score = 82.7 bits (201), Expect = 7e-15
Identities = 105/393 (26%), Positives = 171/393 (42%), Gaps = 39/393 (9%)
Query: 21 LLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVA---HRSYVGNMMDKDFLWSVVER 77
+LG G+L + +A+ A LGV+V ++ A APA A H Y + D L +
Sbjct: 11 ILGGGQLAQMLALAALPLGVQVRVLEPDAEAPARLCAEHVHAPYT-DPAGLDALAAC--- 66
Query: 78 EKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKVPTSRYM 137
DA+ E E + +++L + + V P A + HR R + L +EA T+ ++
Sbjct: 67 ---DAVTLEFENVPVESL-DALRGRVPVRPGAGLLARSKHRAREKAAL-QEAGARTAPFV 121
Query: 138 YATTLDELYEACEKIGYPCHTK-AIMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAEKI 196
+L A +++G K + + GKG V D+ + W E A
Sbjct: 122 VIQREADLDGALDRVGGQGILKTSELGYDGKGQVRVASDTDLRQGWAELGQVA------C 175
Query: 197 IVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAEREV 256
I+E + F+ E++ R D F V + DG S PA + + E
Sbjct: 176 ILEGFVTFEREVSLAVARTADGR----LAFGPLVENVHRDGILRTSVYPAAVPDGTEARA 231
Query: 257 YRIAKRITDVLGGLGLFGVEMF-VKGDKVWANEVSPRPHDTGMVTLASHPPGFSEFGLHL 315
+A+ + + G GL +E F V + NEV+PR H++G +T G S+F +
Sbjct: 232 REMARAVAEGWGLEGLLTLEFFQVPDGDLLVNEVAPRVHNSGHLT--QDGGGASQFEAQV 289
Query: 316 RAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVKGYSPRFRGLAKALSVPNATVRLFGK 375
RAVLGLP+ +W L+P A V V+G +P + + ++P V L+ K
Sbjct: 290 RAVLGLPL-SDW-------SPLLPCAM-VNYVGVEGAAPDWAAID---ALPGTRVHLYHK 337
Query: 376 PEAYVGRRLGVVLAWDKDVQEAKKRAEMVAHMI 408
GR+LG V D+ +R + +I
Sbjct: 338 AHR-TGRKLGHVNLAAPDLPTLHQRLAQLEQLI 369
>pir||G82967 phosphoribosylaminoimidazole carboxylase PA5425 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9951753|gb|AAG08810.1|AE004955_4 (AE004955)
phosphoribosylaminoimidazole carboxylase [Pseudomonas
aeruginosa]
Length = 360
Score = 71.8 bits (173), Expect = 1e-11
Identities = 82/307 (26%), Positives = 138/307 (44%), Gaps = 20/307 (6%)
Query: 18 KILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVER 77
KI ++G G+LG+ +A+ LG+ +D +A A + + D++ L + +
Sbjct: 2 KIGVIGGGQLGRMLALAGTPLGMNFAFLDPAPDACAASLGEHIRA-DYGDQEHLRQLAD- 59
Query: 78 EKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKVPTSRYM 137
+ D + E E++ + + F + V PNA + IA R +++ K+ +PT +
Sbjct: 60 -EVDLVTFEFESVPAETV-AFLSQFVPVYPNAESLRIARDRW-FEKSMFKDLGIPTPDFA 116
Query: 138 YATTLDELYEACEKIGYPCHTKA-IMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAEKI 196
+ +L A IG P K + GKG ++ P D+ A+ E +
Sbjct: 117 DVQSQADLDAAAAAIGLPAVLKTRTLGYDGKGQKVLRQPADVQGAFAEL------GSVPC 170
Query: 197 IVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAEREV 256
I+E + F E++ +AVR D GE T F V + G S + +A E
Sbjct: 171 ILEGFVPFTGEVSLVAVRARD--GE--TRFYPLVHNTHDSGILKLSVASSGHPLQALAED 226
Query: 257 YRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPPGFSEFGLHLR 316
Y R+ L +G+ E F + ANE++PR H++G T+ S+F HLR
Sbjct: 227 Y--VGRVLARLDYVGVLAFEFFEVDGGLKANEIAPRVHNSGHWTIEG--AECSQFENHLR 282
Query: 317 AVLGLPI 323
AV GLP+
Sbjct: 283 AVAGLPL 289
>sp|P72158|PURK_PSEAE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE ATPASE SUBUNIT (AIR
CARBOXYLASE) (AIRC) >gi|1621601|gb|AAB17258.1| (U58364)
PurK [Pseudomonas aeruginosa]
Length = 360
Score = 70.2 bits (169), Expect = 4e-11
Identities = 78/310 (25%), Positives = 136/310 (43%), Gaps = 26/310 (8%)
Query: 18 KILLLGSGELGKEIAIEAQRLGVEVIAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVER 77
KI ++G G+LG+ +A+ LG+ +D +A A + + D++ L + +
Sbjct: 2 KIGVIGGGQLGRMLALAGTPLGMNFAFLDPAPDACAASLGEHIRA-DYGDQEHLRQLAD- 59
Query: 78 EKPDAIIPEIEAINLDALFEFEKEGYFVVPNARATWIAMHRERLRETLVKEAKVPTSRYM 137
+ D + E E++ + + F + V PNA + IA R +++ K+ +PT +
Sbjct: 60 -EVDLVTFEFESVPAETV-AFLSQFVPVYPNAESLRIARDRW-FEKSMFKDLGIPTPDFA 116
Query: 138 YATTLDELYEACEKIGYPCHTKA-IMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAEKI 196
+ ++ A IG P K + GKG ++ P D+ A+ E +
Sbjct: 117 DVQSQADVDAAAAAIGVPAVLKTRTLGYDGKGQKVLRQPADVQGAFAEL------GSVPC 170
Query: 197 IVEEHIDFDVEITELAVRHFDENGEIVTTFPKPVGHYQIDGDY---HASWQPAEISEKAE 253
I+E + F E++ +AVR D + P+ H D + + AE
Sbjct: 171 ILEGFVPFTGEVSLVAVRARDGETRLY-----PLVHNTHDSGILKLSVASSAHPLQALAE 225
Query: 254 REVYRIAKRITDVLGGLGLFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPPGFSEFGL 313
V R+ R+ V G+ E F + ANE++PR H++G T+ S+F
Sbjct: 226 DYVGRVLARLDYV----GVLAFEFFEVDGGLKANEIAPRVHNSGHWTIEG--AECSQFEN 279
Query: 314 HLRAVLGLPI 323
HLRAV GLP+
Sbjct: 280 HLRAVAGLPL 289
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.318 0.136 0.406
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 167917006
Number of Sequences: 2977
Number of extensions: 7369380
Number of successful extensions: 23195
Number of sequences better than 1.0e-10: 50
Number of HSP's better than 0.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 23013
Number of HSP's gapped (non-prelim): 55
length of query: 429
length of database: 189,106,746
effective HSP length: 56
effective length of query: 373
effective length of database: 155,591,474
effective search space: 58035619802
effective search space used: 58035619802
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 166 (69.1 bits)