BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1288 (GNPTA) DE:UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE
N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE (EC 2.7.8.15) (GPT) (G1PT)
(N-ACETYLGLUCOSAMINE-1-PHOSPHATE TRANSFERASE) (GLCNAC-1-P
TRANSFERASE).
(295 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||D75010 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetyl... 569 e-161
pir||A71142 probable UDP-N-acetylglucosamine-dolichyl-phosphate ... 389 e-107
pir||H64438 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetyl... 165 5e-40
pir||C69178 N-acetylglucosamine-1-phosphate transferase - Methan... 160 2e-38
pir||S75428 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetyl... 151 8e-36
gb|AAK40422.1| UDP-N-acetylglucosamine--dolichyl-phosphate N-ace... 151 8e-36
sp|P39465|GPT_SULAC PUTATIVE UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-P... 142 4e-33
pir||A55856 llm protein - Staphylococcus aureus >gi|4433370|dbj|... 101 1e-20
sp|O07322|MRAY_STAAU PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANS... 99 8e-20
gb|AAC45625.1| (U94706) phospho-N-muramic acid-pentapeptide tran... 97 3e-19
pir||B69721 teichoic acid linkage unit synthesis tagO - Bacillus... 96 4e-19
sp|O66465|MRAY_AQUAE PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANS... 94 3e-18
sp|Q9WY77|MRAY_THEMA PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANS... 92 6e-18
pir||T50678 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetyl... 89 6e-17
pir||T45800 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetyl... 89 6e-17
gi|6681215 dolichyl-phosphate alpha-N-acetylglucosaminephosphotr... 89 8e-17
sp|P24140|GPT_CRIGR UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE ... 89 8e-17
gi|4557531 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylg... 89 8e-17
pir||T02444 UDP-N-acetylglucosamine--dolichyl-phosphate-N-acetyl... 89 8e-17
emb|CAB39070.2| (AL034559) N-acetylglucosamine-1-phosphate trans... 88 1e-16
sp|Q44776|MRAY_BORBU PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANS... 88 1e-16
sp|P23338|GPT_CRILO UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE ... 87 2e-16
sp|Q9ZHA5|MRAY_STRPN PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANS... 85 1e-15
emb|CAA65292.1| (X96432) phospho-N-acetylmuramoyl-pentapeptide- ... 81 2e-14
sp|P57314|MRAY_BUCAI PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANS... 79 7e-14
pir||H83094 phospho-N-acetylmuramoyl-pentapeptide- transferase P... 78 9e-14
gb|AAG22121.1| (AY008276) phospho-N-acetylmuramoyl-pentapeptide ... 78 9e-14
sp|Q03521|MRAY_BACSU PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANS... 77 2e-13
sp|Q9ZCW0|MRAY_RICPR PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANS... 77 2e-13
gb|AAF53252.1| (AE003639) CG5287 gene product [Drosophila melano... 77 3e-13
dbj|BAA82114.1| (AB022909) RgpG [Streptococcus mutans] 76 5e-13
sp|P42881|GPT_SCHPO UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE ... 76 5e-13
pir||E81736 phospho-N-acetylmuramoyl-pentapeptide- transferase T... 75 8e-13
pir||H82081 phospho-N-acetylmuramoyl-pentapeptide- transferase V... 75 1e-12
sp|O84762|MRAY_CHLTR PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANS... 75 1e-12
emb|CAB60399.1| (AL117207) contains similarity to Pfam domain: P... 75 1e-12
gi|6319720 UDP-N-acetyl-glucosamine-1-P transferase (GPT); Alg7p... 74 2e-12
pir||G81387 phospho-N-acetylmuramoyl-pentapeptide-transferase (E... 74 2e-12
sp|P45062|MRAY_HAEIN PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANS... 73 3e-12
pir||E81200 phospho-N-acetylmuramoyl-pentapeptide- transferase N... 73 3e-12
sp|Q9Z706|MRAY_CHLPN PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANS... 73 4e-12
pir||A81519 phospho-N-acetylmuramoyl-pentapeptide- transferase C... 73 4e-12
pir||F81777 phospho-N-acetylmuramoyl-pentapeptide-transferase (E... 73 5e-12
gb|AAC35916.1| (AF071085) Orfde3 [Enterococcus faecalis] 71 2e-11
pir||B82763 phospho-N-acetylmuramoyl-pentapeptide- transferase X... 69 5e-11
>pir||D75010 UDP-N-acetylglucosamine--dolichyl-phosphate
N-acetylglucosaminephosphotransferase (EC 2.7.8.15)
PAB1288 - Pyrococcus abyssi (strain Orsay)
>gi|5459036|emb|CAB50522.1| (AJ248288)
UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE
N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE (EC 2.7.8.15)
(GPT) (G1PT) (N-ACETYLGLUCOSAMINE-1-PHOSPHATE
TRANSFERASE) (GLCNAC-1-P TRANSFERASE). [Pyrococcus
abyssi]
Length = 295
Score = 569 bits (1450), Expect = e-161
Identities = 295/295 (100%), Positives = 295/295 (100%)
Query: 1 MIYELLAFALSLALTPYIAKLMKNAGIVGIDVHKVEKVEVPEMGGLALLISISLVSLLAK 60
MIYELLAFALSLALTPYIAKLMKNAGIVGIDVHKVEKVEVPEMGGLALLISISLVSLLAK
Sbjct: 1 MIYELLAFALSLALTPYIAKLMKNAGIVGIDVHKVEKVEVPEMGGLALLISISLVSLLAK 60
Query: 61 INGWILAVFLLMGLVGVIDDSVALKQSHKVLLSIMATFPIVAYINRDYIVIIKPIHVGVL 120
INGWILAVFLLMGLVGVIDDSVALKQSHKVLLSIMATFPIVAYINRDYIVIIKPIHVGVL
Sbjct: 61 INGWILAVFLLMGLVGVIDDSVALKQSHKVLLSIMATFPIVAYINRDYIVIIKPIHVGVL 120
Query: 121 AVLVLWMYVVASTNLVNMLAGFNGLEVGMSSVILFFIAILGEGSVRMLALIGLFASLGFL 180
AVLVLWMYVVASTNLVNMLAGFNGLEVGMSSVILFFIAILGEGSVRMLALIGLFASLGFL
Sbjct: 121 AVLVLWMYVVASTNLVNMLAGFNGLEVGMSSVILFFIAILGEGSVRMLALIGLFASLGFL 180
Query: 181 YWNKYPAKVFPGDTGTLSLGTLIGLLAILGKLEFPVAIMLIPHALDFVLKAKVRFKGKQI 240
YWNKYPAKVFPGDTGTLSLGTLIGLLAILGKLEFPVAIMLIPHALDFVLKAKVRFKGKQI
Sbjct: 181 YWNKYPAKVFPGDTGTLSLGTLIGLLAILGKLEFPVAIMLIPHALDFVLKAKVRFKGKQI 240
Query: 241 GRTRVLEDGTLVPPPYKSFLGLLMRIKPMKEWELVLASIAIEFFLGIVALLIQLA 295
GRTRVLEDGTLVPPPYKSFLGLLMRIKPMKEWELVLASIAIEFFLGIVALLIQLA
Sbjct: 241 GRTRVLEDGTLVPPPYKSFLGLLMRIKPMKEWELVLASIAIEFFLGIVALLIQLA 295
>pir||A71142 probable UDP-N-acetylglucosamine-dolichyl-phosphate
N-AceGluNH-phosphotransferase - Pyrococcus horikoshii
>gi|3256739|dbj|BAA29422.1| (AP000002) 273aa long
hypothetical UDP-N-acetylglucosamine-dolichyl-phosphate
N-AceGluNH-phosphotransferase [Pyrococcus horikoshii]
Length = 273
Score = 389 bits (989), Expect = e-107
Identities = 187/272 (68%), Positives = 231/272 (84%), Gaps = 1/272 (0%)
Query: 22 MKNAGIVGIDVHKVEKVEVPEMGGLALLISISLVSLLAKINGWILAVFLLMGLVGVIDDS 81
MK AGIVGIDVHK++K EVPEMGGLALL+SISLV+L W++++FLL+GLVG++DD
Sbjct: 1 MKKAGIVGIDVHKLDKREVPEMGGLALLLSISLVALALVRADWVVSIFLLVGLVGILDDL 60
Query: 82 VALKQSHKVLLSIMATFPIVAYINRDYIVIIK-PIHVGVLAVLVLWMYVVASTNLVNMLA 140
V L+QSHKV+L+ +T P++ YI R+YI I+ I +G++A+LV W+Y+V S NLVNMLA
Sbjct: 61 VNLRQSHKVILTFFSTSPLLFYIKRNYITILALKIKLGIIALLVFWLYIVVSANLVNMLA 120
Query: 141 GFNGLEVGMSSVILFFIAILGEGSVRMLALIGLFASLGFLYWNKYPAKVFPGDTGTLSLG 200
GFNGLEVG SS+I IA+L EG VR LAL+ FASLGFLYWN+YPA++FPGDTGTLSLG
Sbjct: 121 GFNGLEVGTSSIIFLVIALLSEGDVRKLALVAFFASLGFLYWNRYPARIFPGDTGTLSLG 180
Query: 201 TLIGLLAILGKLEFPVAIMLIPHALDFVLKAKVRFKGKQIGRTRVLEDGTLVPPPYKSFL 260
LIG+LAILG+LEFPVAIMLIPH +DF+LKA+VRFKGK +GRTRVLEDGTLVPPPY SFL
Sbjct: 181 ALIGILAILGELEFPVAIMLIPHTIDFLLKARVRFKGKSLGRTRVLEDGTLVPPPYPSFL 240
Query: 261 GLLMRIKPMKEWELVLASIAIEFFLGIVALLI 292
G+LMR+KPMKEWELVL + +E LGI+A+L+
Sbjct: 241 GMLMRVKPMKEWELVLTVLFLEACLGILAILL 272
>pir||H64438 UDP-N-acetylglucosamine--dolichyl-phosphate
N-acetylglucosaminephosphotransferase (EC 2.7.8.15) -
Methanococcus jannaschii >gi|1591753|gb|AAB99115.1|
(U67554) N-acetylglucosamine-1-phosphate transferase
[Methanococcus jannaschii]
Length = 301
Score = 165 bits (414), Expect = 5e-40
Identities = 109/301 (36%), Positives = 169/301 (55%), Gaps = 21/301 (6%)
Query: 3 YELLAFALSLALTPYIAKLMKNAGIVGIDVHKVEKVEVPEMGGLALLISISLVSLLAKIN 62
Y ++AF S L ++ K M N G D+HK EK++VPEMGGLA+L S +L + +N
Sbjct: 11 YTIIAFIFSAVLCKFLMKKMINYKF-GYDLHKKEKIKVPEMGGLAVLFSNAL--FIPFVN 67
Query: 63 GWILAVFLLMGLVGVIDDSVALKQSHKVLLSIMATFPI-VAYINRDYIVIIKPIHVGVLA 121
+ + G++G++DD L K++L ++ I + + N Y+ +I+
Sbjct: 68 PIFVLPIITAGIIGIVDDIAKLSPKEKLILLFISGLIIGILFYNNSYVNLIE-------- 119
Query: 122 VLVLWMYVVASTNLVNMLAGFNGLEVGM---SSVILFFIAILGEGSVRMLALIGLFAS-L 177
+L++ + ++ S+NL NMLAGFNGLE+GM +S+ L + L + L+ + AS L
Sbjct: 120 ILIIALGIMISSNLTNMLAGFNGLEIGMGVIASISLALVLFLDNYTTGFLSALIFSASYL 179
Query: 178 GFLYWNKYPAKVFPGDTGTLSLGTLIGLLAILGKLEFPVAIMLIPHALDFVLK---AKVR 234
G L +NKYPAKVFPGD GTL +G + +LA++ K P ++++P+ +D LK A V
Sbjct: 180 GLLIFNKYPAKVFPGDVGTLPIGAFLAVLAVVYKEYIPFLVIMMPYVIDASLKYLSAGVM 239
Query: 235 FKGKQIGRTRVLEDGTL-VPPPYKSFLGLLMRIKPMKEWELVLASIAIEFFLGIVALLIQ 293
+ + T + EDG L Y S L+++ KPM+E LV I F GIV +LI
Sbjct: 240 SRDEH-KPTTLKEDGKLYYIGGYLSLPRLILKYKPMREPHLVTVLWIIGIFFGIVGILIS 298
Query: 294 L 294
L
Sbjct: 299 L 299
>pir||C69178 N-acetylglucosamine-1-phosphate transferase - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621669|gb|AAB85096.1| (AE000841)
N-acetylglucosamine-1-phosphate transferase
[Methanobacterium thermoautotrophicum]
Length = 332
Score = 160 bits (400), Expect = 2e-38
Identities = 99/305 (32%), Positives = 169/305 (54%), Gaps = 28/305 (9%)
Query: 5 LLAFALSLALTPYIAKLMKNAGIVGIDVHKVEKVEVPEMGGLALLISISLVSLLAKING- 63
++AF + + P + +K A +VG D+HK+ K V EMGG+ +L ++ +
Sbjct: 30 IIAFTSTYTVMPRLINKLKEANVVGNDIHKISKPIVAEMGGIGILFGFTIGMFIGMYCFP 89
Query: 64 -------WILAVFLLMGLVGVIDDSVALKQSHKVLLSIMATFPIVAYINRDYIVIIKPIH 116
L V LL+G+VG++DD V L K+ L +A PI+ + P
Sbjct: 90 ELQYELMVTLLVILLVGIVGMVDDLVRLSSREKLFLLFLAGLPIIW---------VAPPK 140
Query: 117 VGVLAVLVLWMYVVASTNLVNMLAGFNGLEVGMSSVILFFIA----ILGEGSVRMLALIG 172
VG+L ++++ + V ++NL NMLAG NG+E G+ S+ + + I+G+ V ++ +
Sbjct: 141 VGILYMIMMPVAVSIASNLTNMLAGLNGIESGLGSIAMTALTASCIIMGKYDVSIITMAM 200
Query: 173 LFASLGFLYWNKYPAKVFPGDTGTLSLGTLIGLLAILGKLEFPVAIMLIPHALDFVLK-- 230
L A L FL +N+YP++VFPGD GTL +G I +A +G+++ I+L+P+ +D +LK
Sbjct: 201 LGALLAFLMYNRYPSRVFPGDVGTLIIGACIASVAFIGRVKIIALIVLLPNIIDGILKFY 260
Query: 231 -AKVRFKGKQIGRTRVLEDGTLVPPP--YKSFLGLLMRIKPMKEWELVLASIAIEFFLGI 287
A V + K T + EDG L+ PP + S + ++R +PM E ++V+ +I F G
Sbjct: 261 SAGVVERHKH-RPTEIAEDGKLIAPPEGFNSLIRWILR-RPMTEKKVVMIVWSIGMFFGF 318
Query: 288 VALLI 292
+ +L+
Sbjct: 319 LGVLL 323
>pir||S75428 UDP-N-acetylglucosamine--dolichyl-phosphate
N-acetylglucosaminephosphotransferase (EC 2.7.8.15) -
Sulfolobus solfataricus >gi|1707834|emb|CAA69542.1|
(Y08257) UDP-N-acetylglucosamine-dolichyl-P
N-AcGluNH-phosphotransferase [Sulfolobus solfataricus]
Length = 322
Score = 151 bits (378), Expect = 8e-36
Identities = 97/309 (31%), Positives = 169/309 (54%), Gaps = 23/309 (7%)
Query: 5 LLAFALSLALTPYIAKLMKNAGIVGIDVHKVEKVEVPEMGGLALLI-----SISLVSLLA 59
L++F +S T ++ + K + VG D++K +K E+P +GG+ ++ S SL+
Sbjct: 11 LISFFISYITTVWVIRQAKKSRFVGKDINKPDKPEIPLLGGIGIIAGFIAGSFSLLLTDV 70
Query: 60 KINGWILAVFL---LMGLVGVIDDSVALKQSHKVLLSIMATFPIVAYINRDYIVIIK--- 113
+ I AV L L+ +G++DD ++QS + L I A+ P++ Y I+ I
Sbjct: 71 RSERVIPAVILSSLLIAFLGLLDDIFNVRQSVRAFLPIFASVPLIVYSVGHSIISIPFLG 130
Query: 114 PIHVGVLAVLVLWMYVVAST-NLVNMLAGFNGLEVGMSSVILFFIAILG------EGSVR 166
PI+ G+ +++ + + T N NML G NGL VGM ++L +A +G
Sbjct: 131 PINFGIFYYIIIIPFALTITSNAFNMLEGLNGLGVGMGIIMLSALAYIGLTHTGPTYQAG 190
Query: 167 MLALIGLFASLGFLYWNKYPAKVFPGDTGTLSLGTLIGLLAILGKLEFPVAIMLIPHALD 226
++AL +F+ FL +NKYPAK+FPG+ GT +G LIG + I G + +AI+ IP+ ++
Sbjct: 191 LIALSAIFSLSAFLIFNKYPAKIFPGNVGTYFIGALIGAIGIAGFMYTALAILYIPYVVE 250
Query: 227 FVLKAKVRFKGKQIGRTRVLEDGTLV--PPPYKSFLGLLMRIKPMKEWELVLASIAIEFF 284
F+LK + FKG G +V G L P+ S ++M++ KE+++V+ +E
Sbjct: 251 FILKLRTNFKGVSFG--KVDSSGRLYWDEKPH-SLTHIVMKMGRFKEYQVVIILWGMEAI 307
Query: 285 LGIVALLIQ 293
++A+++Q
Sbjct: 308 FAVIAVILQ 316
>gb|AAK40422.1| UDP-N-acetylglucosamine--dolichyl-phosphate
N-acetylglucosaminephosphotransferase (gnptA)
[Sulfolobus solfataricus]
Length = 322
Score = 151 bits (378), Expect = 8e-36
Identities = 97/309 (31%), Positives = 169/309 (54%), Gaps = 23/309 (7%)
Query: 5 LLAFALSLALTPYIAKLMKNAGIVGIDVHKVEKVEVPEMGGLALLI-----SISLVSLLA 59
L++F +S T ++ + K + VG D++K +K E+P +GG+ ++ S SL+
Sbjct: 11 LISFFISYITTVWVIRQAKKSRFVGKDINKPDKPEIPLLGGIGIIAGFIAGSFSLLLTDV 70
Query: 60 KINGWILAVFL---LMGLVGVIDDSVALKQSHKVLLSIMATFPIVAYINRDYIVIIK--- 113
+ I AV L L+ +G++DD ++QS + L I A+ P++ Y I+ I
Sbjct: 71 RSERVIPAVILSSLLIAFLGLLDDIFNVRQSVRAFLPIFASVPLIVYSVGHSIISIPFLG 130
Query: 114 PIHVGVLAVLVLWMYVVAST-NLVNMLAGFNGLEVGMSSVILFFIAILG------EGSVR 166
PI+ G+ +++ + + T N NML G NGL VGM ++L +A +G
Sbjct: 131 PINFGIFYYIIIIPFALTITSNAFNMLEGLNGLGVGMGIIMLSALAYIGLTHTGPTYQAG 190
Query: 167 MLALIGLFASLGFLYWNKYPAKVFPGDTGTLSLGTLIGLLAILGKLEFPVAIMLIPHALD 226
++AL +F+ FL +NKYPAK+FPG+ GT +G LIG + I G + +AI+ IP+ ++
Sbjct: 191 LIALSAIFSLSAFLIFNKYPAKIFPGNVGTYFIGALIGAIGIAGFMYTALAILYIPYVVE 250
Query: 227 FVLKAKVRFKGKQIGRTRVLEDGTLV--PPPYKSFLGLLMRIKPMKEWELVLASIAIEFF 284
F+LK + FKG G +V G L P+ S ++M++ KE+++V+ +E
Sbjct: 251 FILKLRTNFKGVSFG--KVDSSGRLYWDEKPH-SLTHIVMKMGRFKEYQVVIILWGMEAI 307
Query: 285 LGIVALLIQ 293
++A+++Q
Sbjct: 308 FAVIAVILQ 316
>sp|P39465|GPT_SULAC PUTATIVE UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE
N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE (GPT) (G1PT)
(N-ACETYLGLUCOSAMINE-1-PHOSPHATE TRANSFERASE)
(GLCNAC-1-P TRANSFERASE) >gi|625955|pir||B54058
UDP-N-acetylglucosamine--dolichyl-phosphate
N-acetylglucosaminephosphotransferase (EC 2.7.8.15) -
Sulfolobus acidocaldarius >gi|506372|dbj|BAA05941.1|
(D28748) UDP-N-acetylglucosamine--dolichyl-phosphate
N-acetylglucosaminephosphotransferase [Sulfolobus
acidocaldarius]
Length = 328
Score = 142 bits (355), Expect = 4e-33
Identities = 95/312 (30%), Positives = 161/312 (51%), Gaps = 25/312 (8%)
Query: 5 LLAFALSLALTPYIAKLMKNAGIVGIDVHKVEKVEVPEMGGLA------------LLISI 52
++ F ++L T ++ L K G G D++K+ K +VP +GG+ LL S
Sbjct: 13 IVGFVVTLISTKWVIGLCKKRGFTGKDINKLTKDDVPVLGGIGIVAGFVAGSFTFLLTSY 72
Query: 53 SLVSLLAKINGWILAVFLLMGLVGVIDDSVALKQSHKVLLSIMATFPIVAYINRDYIVII 112
+L + + IL L++G +G++DD + Q+ + L I A+ P++ Y I+ I
Sbjct: 73 NLSPGIENVVVSILLSSLIIGFLGLLDDIFNISQATRAFLPIFASIPLILYSVGHTIISI 132
Query: 113 K---PIHVGVLA-VLVLWMYVVASTNLVNMLAGFNGLEVGMSSVILFFIAILGEGS---- 164
++ G+L +++L + + N NML G NGL GM ++ +A +G S
Sbjct: 133 PFLGKVNFGILFYIIILPATLTITANAFNMLEGLNGLGAGMGLIMALALAYIGLKSGGTS 192
Query: 165 --VRMLALIGLFASLGFLYWNKYPAKVFPGDTGTLSLGTLIGLLAILGKLEFPVAIMLIP 222
++++I GFL +N YPAK FPG+ GT +G++IG + I G + + + +P
Sbjct: 193 FYAGIVSIILASVLFGFLIFNFYPAKTFPGNIGTYFIGSVIGSIGISGYMYTALFFLYLP 252
Query: 223 HALDFVLKAKVRFKGKQIGRTRVLEDGTL-VPPPYKSFLGLLMRIKPMKEWELVLASIAI 281
+ ++FVLKAK RFKG G ++ + G L S ++MRI KE+ +VL I
Sbjct: 253 YVIEFVLKAKTRFKGVSFG--KIDDQGYLHWDSKPNSLTHIVMRIGKFKEYHIVLIIWGI 310
Query: 282 EFFLGIVALLIQ 293
E I+A++ Q
Sbjct: 311 EILFAILAVVFQ 322
>pir||A55856 llm protein - Staphylococcus aureus >gi|4433370|dbj|BAA22521.1|
(D21131) lipophilic protein which affects bacterial
lysis rate and methicillin resistance level
[Staphylococcus aureus]
Length = 351
Score = 101 bits (248), Expect = 1e-20
Identities = 72/233 (30%), Positives = 125/233 (52%), Gaps = 21/233 (9%)
Query: 10 LSLALTPYIAKLMKNAGIVGI-DVHKVEKVEVPEMGGLALLISISLVSLLA-----KING 63
+SL +TP + + K +V + KV + MGG +L S + + +I
Sbjct: 13 VSLTITPIVIAISKRLNLVDKPNFRKVHTKPISVMGGTVILFSFLIGIWIGHPIETEIKP 72
Query: 64 WILAVFLLMGLVGVIDDSVALKQSHKVLLSIMATFPIVAY-INRDYIVIIK--PIHVGVL 120
I+ ++M ++G++DD LK K+ I A + Y + D+I + IH G L
Sbjct: 73 LIIGA-IIMYVLGLVDDIYDLKPYIKLAGQIAAALVVAFYGVTIDFISLPMGTTIHFGFL 131
Query: 121 AVLVLWMYVVASTNLVNMLAGFNGLEVGMSSVILF---FIAILGEGS-VRMLALIGLFAS 176
++ + +++VA TN +N++ G +GL G+S++ L FIAIL + M+ + L +
Sbjct: 132 SIPITVIWIVAITNAINLIDGLDGLASGVSAIGLITIGFIAILQANIFITMICCVLLGSL 191
Query: 177 LGFLYWNKYPAKVFPGDTGTLSLGTLIGLLAILG-------KLEFPVAIMLIP 222
+GFL++N +PAK+F GD+G L +G +IG L++LG L FP+ I+ +P
Sbjct: 192 IGFLFYNFHPAKIFLGDSGALMIGFIIGFLSLLGFKNITIIALFFPIVILAVP 244
>sp|O07322|MRAY_STAAU PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE
(UDP-MURNAC-PENTAPEPTIDE PHOSPHOTRANSFERASE)
>gi|2463562|dbj|BAA22555.1| (AB007500) MRAY
[Staphylococcus aureus] >gi|4104230|gb|AAD01977.1|
(AF034153) phospho-N-acetylmuramoyl-pentapeptide
translocase [Staphylococcus aureus]
Length = 321
Score = 98.7 bits (242), Expect = 8e-20
Identities = 91/332 (27%), Positives = 152/332 (45%), Gaps = 58/332 (17%)
Query: 2 IYELLAFALSLALTPYIAKLMKNAGIVGIDVHK------VEKVEVPEMGGLALLISISLV 55
+Y LLA ++ L P + +K G + + ++K P MGGL L+SI +
Sbjct: 4 VYALLALVITFVLVPVLIPTLKRMKF-GQSIREEGPQSHMKKTGTPTMGGLTFLLSIVIT 62
Query: 56 SLLAKI-----NGWILAVFLLMG--LVGVIDDSVAL----------KQSHKVLLSIMATF 98
SL+A I N IL +F+ +G L+G IDD + + KQ + I F
Sbjct: 63 SLVAIIFVDQANPIILLLFVTIGFGLIGFIDDYIIVVKKNNQGLTSKQKFLAQIGIAIIF 122
Query: 99 PIVAY----------INRDYIVIIKPIHVGVLAVLVLWMYVVASTNLVNMLAGFNGLEVG 148
+++ I+ + + P+ + +V W V +N VN+ G +GL G
Sbjct: 123 FVLSNVFHLVNFSTSIHIPFTNVAIPLSFAYVIFIVFWQ--VGFSNAVNLTDGLDGLATG 180
Query: 149 MSSVILFFIAI----LGEGSVRMLALIGLFASLGFLYWNKYPAKVFPGDTGTLSLGTLIG 204
+S + AI LGE ++ + +I LFA LGFL +N PAKVF GDTG+L+LG +
Sbjct: 181 LSIIGFTMYAIMSFVLGETAIGIFCIIMLFALLGFLPYNINPAKVFMGDTGSLALGGIFA 240
Query: 205 LLAILGKLEFP---VAIMLIPHALDFVLK-AKVRFKGKQIGRTRVLEDGTLVPPPYKSFL 260
++I+ E + ++ + L +L+ A + GK+I + + P + F
Sbjct: 241 TISIMLNQELSLIFIGLVFVIETLSVMLQVASFKLTGKRIFK---------MSPIHHHF- 290
Query: 261 GLLMRIKPMKEWELVLASIAIEFFLGIVALLI 292
+ EW++V A+ G++ L I
Sbjct: 291 ----ELIGWSEWKVVTVFWAVGLISGLIGLWI 318
>gb|AAC45625.1| (U94706) phospho-N-muramic acid-pentapeptide translocase
[Staphylococcus aureus]
Length = 329
Score = 96.7 bits (237), Expect = 3e-19
Identities = 82/280 (29%), Positives = 134/280 (47%), Gaps = 44/280 (15%)
Query: 2 IYELLAFALSLALTPYIAKLMKNAGIVGIDVHK------VEKVEVPEMGGLALLISISLV 55
+Y LLA ++ L P + +K G + + ++K P MGGL L+SI +
Sbjct: 4 VYALLALVITFVLVPVLIPTLKRMKF-GQSIREEGPQSHMKKTGTPTMGGLTFLLSIVIT 62
Query: 56 SLLAKI-----NGWILAVFLLMG--LVGVIDDSVAL----------KQSHKVLLSIMATF 98
SL+A I N IL +F+ +G L+G IDD + + KQ + I F
Sbjct: 63 SLVAIIFVDQANPIILLLFVTIGFGLIGFIDDYIIVVKKNNPGLTSKQKFLAQIGIAIIF 122
Query: 99 PIVAY----------INRDYIVIIKPIHVGVLAVLVLWMYVVASTNLVNMLAGFNGLEVG 148
+++ I+ + + P+ + +V W V +N VN+ G +GL G
Sbjct: 123 FVLSNVFHLVNFSTSIHIPFTNVAIPLSFAYVIFIVFWQ--VGFSNAVNLTDGLDGLATG 180
Query: 149 MSSVILFFIAI----LGEGSVRMLALIGLFASLGFLYWNKYPAKVFPGDTGTLSLGTLIG 204
+S + AI LGE ++ + +I LFA LGFL +N PAKVF GDTG+L+LG +
Sbjct: 181 LSIIGFTMYAIMSFVLGETAIGIFCIIMLFALLGFLPYNINPAKVFMGDTGSLALGGIFA 240
Query: 205 LLAILGKLEFP---VAIMLIPHALDFVLK-AKVRFKGKQI 240
++I+ E + ++ + L +L+ A + GK+I
Sbjct: 241 TISIMLNQELSLIIIGLVFVIETLSVMLQVASFKLTGKRI 280
>pir||B69721 teichoic acid linkage unit synthesis tagO - Bacillus subtilis
>gi|2582651|emb|CAA06152.1| (AJ004803) putative
undecaprenyl-phosphate N-acetylglucosaminyltransferase
[Bacillus subtilis] >gi|2636079|emb|CAB15570.1| (Z99122)
alternate gene name: yvhI [Bacillus subtilis]
Length = 358
Score = 96.3 bits (236), Expect = 4e-19
Identities = 71/250 (28%), Positives = 134/250 (53%), Gaps = 30/250 (12%)
Query: 1 MIYELLAFALSLA----LTPYIAKLMKNAGIVGIDVH-KVEKVEVPEMGGLALLISISLV 55
MI ++AF +SL +TP + ++ G V + KV +P MGGLA+ I + +
Sbjct: 6 MIRIVVAFIVSLLTVLIITPIVKRIAIKIGAVDQPSNRKVHDKIMPRMGGLAIFIGV-VA 64
Query: 56 SLLA-------KINGWILAVFLLMGLVGVIDDSVALKQSHKVLLSIMATFPIVAY-INRD 107
+LA ++ + F+++ ++G++DD L K L+ + IV+ + D
Sbjct: 65 GVLASGIYTETRMTAITVGAFIII-VLGILDDKYQLSAKVKFLIQLGVAIMIVSTGLKMD 123
Query: 108 YIVI---IKPIHVGVLAVLVLWMYVVASTNLVNMLAGFNGLEVGMSSVILFFIAIL---- 160
+ + + +G +A + +++V TN +N++ G +GL G+S + L IA++
Sbjct: 124 FFSVPFLTERFELGWMAYPLTVLWIVGITNAINLIDGLDGLAAGLSVIGLSTIAVMALSG 183
Query: 161 GEGSVRMLALIGLFASLGFLYWNKYPAKVFPGDTGTLSLGTLIGLLAILG--------KL 212
G+ + L+L+ + ++LGFL++N +PAK+F GDTG+L LG I +L++LG +
Sbjct: 184 GKVLILSLSLVVIASTLGFLFYNFHPAKIFMGDTGSLFLGYSISILSLLGLYKSVTLFSI 243
Query: 213 EFPVAIMLIP 222
P+ I+ +P
Sbjct: 244 VIPIIILGVP 253
>sp|O66465|MRAY_AQUAE PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE
(UDP-MURNAC-PENTAPEPTIDE PHOSPHOTRANSFERASE)
>gi|7434928|pir||F70304
phospho-N-acetylmuramoyl-pentapeptide- transferase -
Aquifex aeolicus >gi|2982794|gb|AAC06418.1| (AE000671)
phospho-N-acetylmuramoyl-pentapeptide-transferase
[Aquifex aeolicus]
Length = 359
Score = 93.6 bits (229), Expect = 3e-18
Identities = 83/263 (31%), Positives = 128/263 (48%), Gaps = 52/263 (19%)
Query: 5 LLAFALSLALTP-YIAKLMKNAGIVGIDV-------HKVEKVEVPEMGGLALLISISLVS 56
L+AF L+L L+P +I +L K + G V H+V+K P MGG+ +LI ++L +
Sbjct: 31 LIAFFLTLVLSPSFINRLRKIQRLFGGYVREYTPESHEVKKY-TPTMGGIVILIVVTLST 89
Query: 57 LLA-----KINGWILAVFLLMGLVGVIDDSVALKQSH------KVLLSIMAT--FPIVAY 103
LL K +L FL G +G DD V LK K LL +++ ++ Y
Sbjct: 90 LLLMRWDIKYTWVVLLSFLSFGTIGFWDDYVKLKNKKGISIKTKFLLQVLSASLISVLIY 149
Query: 104 INRD-----YIVIIKPIHV--GVLAVLVLWMYVVASTNLVNMLAGFNGLEVGMS------ 150
D Y K ++V GVL + +V S N VN+ G +GL +G +
Sbjct: 150 YWADIDTILYFPFFKELYVDLGVLYLPFAVFVIVGSANAVNLTDGLDGLAIGPAMTTATA 209
Query: 151 -SVILF--------------FIAILGEGSVRMLALIGLFASLGFLYWNKYPAKVFPGDTG 195
V+ + ++ GE +V AL+G A LGFL++N +PA++F GD G
Sbjct: 210 LGVVAYAVGHSKIAQYLNIPYVPYAGELTVFCFALVG--AGLGFLWFNSFPAQMFMGDVG 267
Query: 196 TLSLGTLIGLLAILGKLEFPVAI 218
+LS+G + +A+L K EF A+
Sbjct: 268 SLSIGASLATVALLTKSEFIFAV 290
>sp|Q9WY77|MRAY_THEMA PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE
(UDP-MURNAC-PENTAPEPTIDE PHOSPHOTRANSFERASE)
>gi|7434929|pir||E72402
phospho-N-acetylmuramoyl-pentapeptide- transferase -
Thermotoga maritima (strain MSB8)
>gi|4980733|gb|AAD35326.1|AE001707_13 (AE001707)
phospho-N-acetylmuramoyl-pentapeptide-transferase
[Thermotoga maritima]
Length = 302
Score = 92.4 bits (226), Expect = 6e-18
Identities = 70/232 (30%), Positives = 113/232 (48%), Gaps = 19/232 (8%)
Query: 8 FALSLALTPYIAKLMKNAGI------VGIDVHKVEKVEVPEMGGLALLISISLVSLLAKI 61
F L+L L P + KL + I G D+H K P MGG+ +++ L +++K
Sbjct: 6 FLLNLFLYPILIKLFRRRRIGQYIRKEGPDLHGY-KEGTPTMGGILFVLTGFLFGMISKT 64
Query: 62 NGWILAVFLLMGLVGVIDD--------SVALKQSHKVLLSIMATFPIVAYINRDYIVII- 112
N +L L L+G +DD S LK K LL +A F ++ I D V
Sbjct: 65 NTMVLLGMFLFFLIGFLDDFLSVARKDSTGLKTYQKALLQTLAAFIMLLLIRPDTNVDFF 124
Query: 113 -KPIHVGVLAVLVLWMYVVASTNLVNMLAGFNGLE--VGMSSVILFFIAILGEGSVRMLA 169
I +G L + +V S+N +N+ G +GL + +S I ++ + G +
Sbjct: 125 GSTIEMGKWYYLFALLVIVGSSNAMNLTDGLDGLAGWIYVSGSIPYWFFLKERGVSEDIL 184
Query: 170 LIGLFASLGFLYWNKYPAKVFPGDTGTLSLGTLIGLLAILGKLEFPVAIMLI 221
LI L FL +N PAK+F GDTG+++LG ++G +++L K EF + + +
Sbjct: 185 LILGVGVLAFLVFNSKPAKIFMGDTGSITLGGVLGTVSVLTKTEFYLVLFFM 236
>pir||T50678 UDP-N-acetylglucosamine--dolichyl-phosphate
N-acetylglucosaminephosphotransferase (EC 2.7.8.15)
[validated] - Arabidopsis thaliana
>gi|5804772|dbj|BAA83586.1| (D88036) UDP-GlcNAc:dolichol
phosphate N-acetylglucosamine-1-phosphate transferase
[Arabidopsis thaliana] >gi|5804774|dbj|BAA83587.1|
(D88037) UDP-GlcNAc:dolichol phosphate
N-acetylglucosamine-1-phosphate transferase [Arabidopsis
thaliana]
Length = 431
Score = 88.9 bits (217), Expect = 6e-17
Identities = 74/268 (27%), Positives = 127/268 (46%), Gaps = 45/268 (16%)
Query: 5 LLAFALSLALTPYIAKLMKNAGIVGIDVHK----VEKVEVPEMGGLALLISISLVSLLAK 60
L+ F ++L + P A+ + + G D++K ++VPE G+ + I +V+++ +
Sbjct: 89 LVGFFVTLKMIPVTARYVLRRNMFGFDINKRGTPQGDIKVPESLGIVVGIVFLIVAIIFQ 148
Query: 61 I------NGWI------LAVFLLMGLVGVIDDSVALKQSHKVLLSIMATFPIV-AYINRD 107
+ W+ LA M L+G +DD + + K++L AT P++ AY
Sbjct: 149 YFNFTEDSNWLVEYNAALASICFMILLGFVDDVLDVPWRVKLVLPSFATLPLLMAYAGHT 208
Query: 108 YIVIIKPI---------HVGVLAVLVLWMYVVASTNLVNMLAGFNGLEVGMSSVILFFIA 158
IVI KP+ ++G + L + + V TN +N+ AG NGLE+G + VI A
Sbjct: 209 TIVIPKPLVAYIGLEVLNLGRIYKLYMGLLAVFCTNSINIHAGLNGLEIGQTVVIA--AA 266
Query: 159 ILGEGSVRMLALIG-----------------LFASLGFLYWNKYPAKVFPGDTGTLSLGT 201
IL +++ A + + SL L +N YP+ VF GDT T+ G
Sbjct: 267 ILIHNVMQIGASVDPEYHQAHAFSIFLTQPLMATSLAMLAYNWYPSSVFVGDTYTVFAGM 326
Query: 202 LIGLLAILGKLEFPVAIMLIPHALDFVL 229
+ ++ ILG + I +P L+F+L
Sbjct: 327 TMAVVGILGHFSETLLIFFLPQVLNFLL 354
>pir||T45800 UDP-N-acetylglucosamine--dolichyl-phosphate
N-acetylglucosaminephosphotransferase (EC 2.7.8.15)
F28O9.70 [similarity] - Arabidopsis thaliana
>gi|6735301|emb|CAB68128.1| (AL137080)
UDP-GlcNAc:dolichol phosphate
N-acetylglucosamine-1-phosphate transferase-like protein
[Arabidopsis thaliana]
Length = 426
Score = 88.9 bits (217), Expect = 6e-17
Identities = 77/268 (28%), Positives = 126/268 (46%), Gaps = 45/268 (16%)
Query: 5 LLAFALSLALTPYIAKLMKNAGIVGIDVHK----VEKVEVPEMGGLALLISISLVSLLAK 60
L+ F ++L L P A+ + + G D++K +V VPE G+ + I +V+++ +
Sbjct: 84 LVGFFVTLKLIPVAARYVLRRNMFGFDINKRGTPQGEVRVPESLGIVVGIVFLIVAIVFQ 143
Query: 61 I------NGWI------LAVFLLMGLVGVIDDSVALKQSHKVLLSIMATFPIV-AYINRD 107
+ W+ LA M L+G +DD + + K+LL AT P++ AY
Sbjct: 144 FFNFTEDSVWLVEYNAALASICFMILLGFVDDVLDVPWRVKLLLPSFATLPLLMAYAGHT 203
Query: 108 YIVIIKPI---------HVGVLAVLVLWMYVVASTNLVNMLAGFNGLEVGMSSVILFFIA 158
IVI KP+ +G + L + + V TN +N+ AG NGLE+G + VI A
Sbjct: 204 TIVIPKPLVSYIGLEVFDLGRIYKLYMALLAVFCTNSINIHAGLNGLEIGQTVVIA--AA 261
Query: 159 ILGEGSVRMLALIG-----------------LFASLGFLYWNKYPAKVFPGDTGTLSLGT 201
IL +++ A + + SL L +N YP+ VF GDT T+ G
Sbjct: 262 ILIHNVMQIGASVDTEYHQAHAFSIYLTQPLMATSLAMLAYNWYPSAVFVGDTYTVFAGM 321
Query: 202 LIGLLAILGKLEFPVAIMLIPHALDFVL 229
+ ++ ILG + I +P L+F+L
Sbjct: 322 TMAVVGILGHFSETLLIFFLPQVLNFLL 349
>gi|6681215 dolichyl-phosphate alpha-N-acetylglucosaminephosphotransferase 2
[Mus musculus] >gi|1170011|sp|P42867|GPT_MOUSE
UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE
N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE (GPT) (G1PT)
(N-ACETYLGLUCOSAMINE-1-PHOSPHATE TRANSFERASE)
(GLCNAC-1-P TRANSFERASE) >gi|109883|pir||S24326
UDP-N-acetylglucosamine--dolichyl-phosphate
N-acetylglucosaminephosphotransferase (EC 2.7.8.15) -
mouse >gi|51078|emb|CAA46553.1| (X65603) GlcNAc-1-P
transferase [Mus musculus]
Length = 410
Score = 88.5 bits (216), Expect = 8e-17
Identities = 74/274 (27%), Positives = 121/274 (44%), Gaps = 47/274 (17%)
Query: 1 MIYELLAFALSLALTPYIAKLMKNAGIVGIDVHKVEKVEVPEM-----GGLALLISISLV 55
+I LL F ++ L P A + G D++K+ + ++PE G + L+I +
Sbjct: 17 LIGSLLGFVATVTLIPAFRSHFIAARLCGQDLNKLSQQQIPESQGVISGAVFLIILFYFI 76
Query: 56 SL------------------LAKINGWILAVFLLMGLVGVIDDSVALKQSHKVLLSIMAT 97
+ G +LA+ ++ L G DD + L+ HK+LL A+
Sbjct: 77 PFPFLNCFVEEQCKAFPHHEFVALIGALLAICCMIFL-GFADDVLNLRWRHKLLLPTAAS 135
Query: 98 FPIVAYINRDY----IVIIKP--------IHVGVLAVLVLWMYVVASTNLVNMLAGFNGL 145
P++ ++ IV+ KP + +G+L + + + V TN +N+LAG NGL
Sbjct: 136 LPLLMVYFTNFGNTTIVVPKPFRWILGLHLDLGILYYVYMGLLAVFCTNAINILAGINGL 195
Query: 146 EVGMSSVILFFIAILG----EGSVRMLALIGL-------FASLGFLYWNKYPAKVFPGDT 194
E G S VI I + EG R + L F +LG LY N YP++VF GDT
Sbjct: 196 EAGQSLVISASIIVFNLVELEGDYRDDHIFSLYFMIPFFFTTLGLLYHNWYPSRVFVGDT 255
Query: 195 GTLSLGTLIGLLAILGKLEFPVAIMLIPHALDFV 228
G ++ ILG + + +P +F+
Sbjct: 256 FCYFAGMTFAVVGILGHFSKTMLLFFMPQVFNFL 289
>sp|P24140|GPT_CRIGR UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE
N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE (GPT) (G1PT)
(N-ACETYLGLUCOSAMINE-1-PHOSPHATE TRANSFERASE)
(GLCNAC-1-P TRANSFERASE) >gi|109434|pir||A23664
UDP-N-acetylglucosamine--dolichyl-phosphate
N-acetylglucosaminephosphotransferase (EC 2.7.8.15) -
Chinese hamster >gi|191229|gb|AAA37027.1| (M36899)
uridine diphosphate N-acetyl D-glucosamine dolichol
phosphate N-acetyl glucosamine-1 phosphate transferase
[Cricetulus griseus]
Length = 408
Score = 88.5 bits (216), Expect = 8e-17
Identities = 74/270 (27%), Positives = 119/270 (43%), Gaps = 47/270 (17%)
Query: 5 LLAFALSLALTPYIAKLMKNAGIVGIDVHKVEKVEVPEM-----GGLALLISISLVSL-- 57
LL F ++ L P A + G D++K+ + ++PE G + L+I +
Sbjct: 19 LLGFVATVTLIPAFRSHFIAARLCGQDLNKLSRQQIPESQGVICGAVFLIILFCFIPFPF 78
Query: 58 ----------------LAKINGWILAVFLLMGLVGVIDDSVALKQSHKVLLSIMATFPIV 101
+ G +LA+ ++ L G DD + L+ HK+LL A+ P++
Sbjct: 79 LNCFVEEQCKAFPHHEFVALIGALLAICCMIFL-GFADDVLNLRWRHKLLLPTAASLPLL 137
Query: 102 AYINRDY----IVIIKP--------IHVGVLAVLVLWMYVVASTNLVNMLAGFNGLEVGM 149
++ IV+ KP + +G+L + + + V TN +N+LAG NGLE G
Sbjct: 138 MVYFTNFGNTTIVVPKPFRWILGLHLDLGILYYVYMGLLAVFCTNAINILAGINGLEAGQ 197
Query: 150 SSVILFFIAILG----EGSVRMLALIGL-------FASLGFLYWNKYPAKVFPGDTGTLS 198
S VI I + EG R + L F +LG LY N YP++VF GDT
Sbjct: 198 SLVISASIIVFNLVELEGDYRDDHVFSLYFMIPFFFTTLGLLYHNWYPSQVFVGDTFCYF 257
Query: 199 LGTLIGLLAILGKLEFPVAIMLIPHALDFV 228
G ++ ILG + + IP +F+
Sbjct: 258 AGMTFAVVGILGHFSKTMLLFFIPQVFNFL 287
>gi|4557531 UDP-N-acetylglucosamine--dolichyl-phosphate
N-acetylglucosaminephosphotransferase;
dolichyl-phosphate
alpha-N-acetylglucosaminyltransferase; GlcNAc-1-P
transferase; UDP-GlcNAc:dolichyl-phosphate
N-acetylglucosaminephosphotransferase;
dolichyl-phosphate> >gi|2239119|emb|CAB04787.1| (Z82022)
GlcNac-1-P transferase [Homo sapiens]
Length = 400
Score = 88.5 bits (216), Expect = 8e-17
Identities = 75/274 (27%), Positives = 120/274 (43%), Gaps = 47/274 (17%)
Query: 1 MIYELLAFALSLALTPYIAKLMKNAGIVGIDVHKVEKVEVPEMGG----------LALLI 50
+I LL F ++ L P A + G D++K + ++PE G L I
Sbjct: 7 LIVSLLGFVATVTLIPAFLGHFIAARLCGQDLNKTSRQQIPESQGVISGAVFLIILFCFI 66
Query: 51 SISLVSLLAK-------------INGWILAVFLLMGLVGVIDDSVALKQSHKVLLSIMAT 97
++ K + G +LA+ ++ L G DD + L+ HK+LL A+
Sbjct: 67 PFPFLNCFVKEQCKAFPHHEFVALIGALLAICCMIFL-GFADDVLNLRWRHKLLLPTAAS 125
Query: 98 FPIVAYINRDY----IVIIKP--------IHVGVLAVLVLWMYVVASTNLVNMLAGFNGL 145
P++ ++ IV+ KP + +G+L + + + V TN +N+LAG NGL
Sbjct: 126 LPLLMVYFTNFGNTTIVVPKPFRPILGLHLDLGILYYVYMGLLAVFCTNAINILAGINGL 185
Query: 146 EVGMSSVILFFIAILG----EGSVRMLALIGL-------FASLGFLYWNKYPAKVFPGDT 194
E G S VI I + EG R + L F +LG LY N YP++VF GDT
Sbjct: 186 EAGQSLVISASIIVFNLVELEGDCRDDHVFSLYFMIPFFFTTLGLLYHNWYPSRVFVGDT 245
Query: 195 GTLSLGTLIGLLAILGKLEFPVAIMLIPHALDFV 228
G ++ ILG + + +P +F+
Sbjct: 246 FCYFAGMTFAVVGILGHFSKTMLLFFMPQVFNFL 279
>pir||T02444 UDP-N-acetylglucosamine--dolichyl-phosphate-N-acetylglucosam
inephosphotransferase homolog T32G6.1 - Arabidopsis
thaliana >gi|2618684|gb|AAB84331.1| (AC002510) putative
UDO-GlcNAc:dolichol phosphate
N-acetylglucosamine-1-phosphate transferase [Arabidopsis
thaliana]
Length = 417
Score = 88.5 bits (216), Expect = 8e-17
Identities = 75/261 (28%), Positives = 123/261 (46%), Gaps = 38/261 (14%)
Query: 5 LLAFALSLALTPYIAKLMKNAGIVGIDVHK----VEKVEVPEMGGLA-----LLISI--- 52
L+ F ++L + P A+ + + G D++K ++VPE G+ L+++I
Sbjct: 89 LVGFFVTLKMIPVTARYVLRRNMFGFDINKRGTPQGDIKVPESLGIVVGIVFLIVAIIFQ 148
Query: 53 -------SLVSLLAKINGWILAVFLLMGLVGVIDDSVALKQSHKVLLSIMATFPIV-AYI 104
S VS L + N LA M L+G +DD + + K++L AT P++ AY
Sbjct: 149 YFNFTEDSNVSWLVEYNA-ALASICFMILLGFVDDVLDVPWRVKLVLPSFATLPLLMAYA 207
Query: 105 NRDYIVIIKPI---------HVGVLAVLVLWMYVVASTNLVNMLAGFNGLEVGMSSVILF 155
IVI KP+ ++G + L + + V TN +N+ AG NGLE+G + VI
Sbjct: 208 GHTTIVIPKPLVAYIGLEVLNLGRIYKLYMGLLAVFCTNSINIHAGLNGLEIGQTVVIAA 267
Query: 156 FIAILGEGSVRMLALIGLF-------ASLGFLYWNKYPAKVFPGDTGTLSLGTLIGLLAI 208
+ + + +F SL L +N YP+ VF GDT T+ G + ++ I
Sbjct: 268 AVTSV-DPEYHQAHAFSIFLTQPLMATSLAMLAYNWYPSSVFVGDTYTVFAGMTMAVVGI 326
Query: 209 LGKLEFPVAIMLIPHALDFVL 229
LG + I +P L+F+L
Sbjct: 327 LGHFSETLLIFFLPQVLNFLL 347
>emb|CAB39070.2| (AL034559) N-acetylglucosamine-1-phosphate transferase [Plasmodium
falciparum]
Length = 397
Score = 88.2 bits (215), Expect = 1e-16
Identities = 82/326 (25%), Positives = 150/326 (45%), Gaps = 49/326 (15%)
Query: 6 LAFALSLALTPYIAKLMKNAGIVGIDVHKVEKVEVPEMGGL--ALLISISLV-------- 55
+ F ++ P + G+ GID++K K V E GL ++L I ++
Sbjct: 60 ILFKVTFICLPKFIHFLNEKGLCGIDLNKSGKEYVAEPIGLFPSILYFIFVLFYQLIYYN 119
Query: 56 --SLLAKINGWILAVFLLMGLVGVIDDSVALKQSHKVLLSIMATFPIVAYINRD------ 107
+L + N +L++ + M +G IDD + LK +KV+L A+ P++ + +
Sbjct: 120 DHRILLEYNAGLLSI-IFMTFLGFIDDILDLKWRYKVILPFFASLPLLLSYSGETHIRIP 178
Query: 108 -YIVII---KPIHVGVLAVLVLWMYVVASTNLVNMLAGFNGLEVGMSSVILFFIAI---- 159
+++ I + I++G L + + + V TN +N+ AG NGLE+G S +I FFI I
Sbjct: 179 NFLIFIFKHRIINIGFLYYVYIILLSVFCTNAINIYAGINGLEIGQSLIISFFITIHNLI 238
Query: 160 -----LGEGSV--------RMLALI----GLFASLGFLYWNKYPAKVFPGDTGTLSLGTL 202
+G+ + L++I L +L +N YP+K F G+T T G
Sbjct: 239 EITLNIGKSPIIENLILKQHFLSIIFTIPFLTINLATFSFNFYPSKGFVGNTLTYFCGMF 298
Query: 203 IGLLAILGKLEFPVAIMLIPHALDFVLKAKVRFKGKQIGRTRV----LEDGTLVPPPYKS 258
+ +++I G + + LIP L+F + F R R+ + L+ +
Sbjct: 299 LAVVSIFGHFSKTLVLFLIPQFLNFFISLPQLFHIIPCPRHRLPIINYKTNKLMYSHNYT 358
Query: 259 FLGLLMRI-KPMKEWELVLASIAIEF 283
+ L++ + P+ E+ LVL + +F
Sbjct: 359 LINLILYLFGPLSEYHLVLILLTFQF 384
>sp|Q44776|MRAY_BORBU PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE
(UDP-MURNAC-PENTAPEPTIDE PHOSPHOTRANSFERASE)
>gi|7434927|pir||G70137
phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY)
homolog - Lyme disease spirochete
>gi|1165287|gb|AAA85626.1| (U43739) MraY [Borrelia
burgdorferi] >gi|2688163|gb|AAC66645.1| (AE001137)
phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY)
[Borrelia burgdorferi]
Length = 351
Score = 87.8 bits (214), Expect = 1e-16
Identities = 79/263 (30%), Positives = 128/263 (48%), Gaps = 48/263 (18%)
Query: 5 LLAFALSLALTPYIAKLMKNAGIV------GIDVHKVEKVEVPEMGGLALL--ISISLVS 56
+ AF LSL + PYI +K G H EK +P MGG+ + + ISLV
Sbjct: 22 IFAFLLSLIVGPYIILKLKKLRADQILREDGPKRHLSEKAGIPTMGGILIFFCVFISLVF 81
Query: 57 LLAKINGWILA-VFLLMGL--VGVIDD--------SVALKQSHKVLLSIMATF---PIVA 102
+N + L VF+++G +G IDD S LK K+ I+ +F I+
Sbjct: 82 WSNILNVYFLIMVFVMLGFAFLGFIDDFLKIKKKTSDGLKARFKIYGQIIFSFFSVGILY 141
Query: 103 YINRDYIVIIK-------PIHVGVLAVLVLWMYVVASTNLVNMLAGFNGLEVGMSSVI-- 153
Y +++ +I I +G+ + +++++N N+ G +GL +G+S VI
Sbjct: 142 YFGGEHVSVIYFPFIKSFQIDLGLFYIPFGMFILISASNSFNLTDGLDGLAIGLSIVITG 201
Query: 154 -LFFIAILG--------------EGSVRMLALIG--LFASLGFLYWNKYPAKVFPGDTGT 196
L IA L +GS ++ +G L S GFL++N YPAK+ GDTG+
Sbjct: 202 ALIIIAYLTSRADFAAYLHIPNIKGSEELVIFLGALLGGSFGFLWFNAYPAKIMMGDTGS 261
Query: 197 LSLGTLIGLLAILGKLEFPVAIM 219
L+LG ++G+ A++ K E +I+
Sbjct: 262 LALGAILGMAALILKSEILFSIL 284
>sp|P23338|GPT_CRILO UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE
N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE (GPT) (G1PT)
(N-ACETYLGLUCOSAMINE-1-PHOSPHATE TRANSFERASE)
(GLCNAC-1-P TRANSFERASE) >gi|109413|pir||A37813
UDP-N-acetylglucosamine--dolichyl-phosphate
N-acetylglucosaminephosphotransferase (EC 2.7.8.15) -
Chinese hamster >gi|304500|gb|AAA36965.1| (J05590)
N-acetylglucosamine-1-phosphate transferase (GPT)
[Cricetulus longicaudatus]
Length = 408
Score = 87.4 bits (213), Expect = 2e-16
Identities = 74/270 (27%), Positives = 118/270 (43%), Gaps = 47/270 (17%)
Query: 5 LLAFALSLALTPYIAKLMKNAGIVGIDVHKVEKVEVPEM-----GGLALLISISLVSL-- 57
LL F ++ L P A + G D++K+ + ++PE G + L+I +
Sbjct: 19 LLGFVATVTLIPAFRSHFIAARLCGQDLNKLSRQQIPESQGVICGAVFLIILFCFIPFPF 78
Query: 58 ----------------LAKINGWILAVFLLMGLVGVIDDSVALKQSHKVLLSIMATFPIV 101
+ G +LA+ ++ L G DD + L HK+LL A+ P++
Sbjct: 79 LNCFVEEQCKAFPHHEFVALIGALLAICCMIFL-GFADDVLNLPWRHKLLLPTAASLPLL 137
Query: 102 AYINRDY----IVIIKP--------IHVGVLAVLVLWMYVVASTNLVNMLAGFNGLEVGM 149
++ IV+ KP + +G+L + + + V TN +N+LAG NGLE G
Sbjct: 138 MVYFTNFGNTTIVVPKPFRWILGLHLDLGILYYVYMGLLAVFCTNAINILAGINGLEAGQ 197
Query: 150 SSVILFFIAILG----EGSVRMLALIGL-------FASLGFLYWNKYPAKVFPGDTGTLS 198
S VI I + EG R + L F +LG LY N YP++VF GDT
Sbjct: 198 SLVISASIIVFNLVELEGDYRDDHVFSLYFMIPFFFTTLGLLYHNWYPSQVFVGDTFCYF 257
Query: 199 LGTLIGLLAILGKLEFPVAIMLIPHALDFV 228
G ++ ILG + + IP +F+
Sbjct: 258 AGMTFAVVGILGHFSKTMLLFFIPQVFNFL 287
>sp|Q9ZHA5|MRAY_STRPN PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE
(UDP-MURNAC-PENTAPEPTIDE PHOSPHOTRANSFERASE)
>gi|4009489|gb|AAC95457.1| (AF068903)
undecaprenyl-phosphate-UDP-MurNAc-pentapeptide
phospho-MurNAc-pentapeptide transferase [Streptococcus
pneumoniae]
Length = 326
Score = 84.7 bits (206), Expect = 1e-15
Identities = 87/331 (26%), Positives = 149/331 (44%), Gaps = 58/331 (17%)
Query: 5 LLAFALSLALTPYIAKLMKNAGIVGIDVHK-----VEKVEVPEMGGLALLISISLVSL-- 57
++ F L+L P + + A I G +H+ K P MGGL LI+ LV+
Sbjct: 9 IVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQAKAGTPTMGGLVFLIASVLVAFFF 68
Query: 58 ------LAKINGWILAVFLLMGLVGVIDDSV--------ALKQSHKVLLSIMATFPIVAY 103
L+ G IL + +L GL+G +DD + L K+ L ++ +
Sbjct: 69 ALFSNQLSNNVGMILFILVLYGLIGFLDDFLKVFRKINEGLNPKQKLALQLLGGVIFYLF 128
Query: 104 INR--DYIVIIK-PIHVGVLAVLVLWMYVVASTNLVNMLAGFNGLEVGMSSVILFFIA-- 158
R D + + P+H+G + ++V +N VN+ G +GL SV++ A
Sbjct: 129 YERGGDILSVFGYPVHLGFFYIFFALFWLVGFSNAVNLTDGVDGL--ASISVVISLSAYG 186
Query: 159 ----ILGEGSVRMLALIGLFASLGFLYWNKYPAKVFPGDTGTLSLGTLIGLLAILGKLEF 214
+ G+ + ++ L + LGF +N PAKVF GD G+L+LG ++ +++ E+
Sbjct: 187 VIAYVQGQMDILLVILAMIGGLLGFFIFNHKPAKVFMGDVGSLALGGMLAAISMALHQEW 246
Query: 215 PVAIMLIPHALD--FVLKAKVRFK---GKQIGRTRVLEDGTLVPPPYKSFL--GLLMRIK 267
+ I+ I + + V+ FK GK+I R + P + F GL +
Sbjct: 247 TLLIIGIVYVFETTSVMMQVSYFKLTGGKRIFR---------MTPVHHHFELGGLSGKGN 297
Query: 268 PMKEWELVLASIAIEFF---LGIVALLIQLA 295
P EW+ ++FF +G++A L+ LA
Sbjct: 298 PWSEWK-------VDFFFWGVGLLASLLTLA 321
>emb|CAA65292.1| (X96432) phospho-N-acetylmuramoyl-pentapeptide- transferase
[Borrelia burgdorferi] >gi|1234872|emb|CAA65460.1|
(X96685) phospho-N-acetylmuramoyl-pentapeptide-
transferase [Borrelia burgdorferi]
Length = 303
Score = 80.8 bits (196), Expect = 2e-14
Identities = 68/229 (29%), Positives = 115/229 (49%), Gaps = 42/229 (18%)
Query: 33 HKVEKVEVPEMGGLALL--ISISLVSLLAKINGWI-LAVFLLMGL--VGVIDD------- 80
H EK +P MGG+ + + ISLV +N + + VF+++G +G IDD
Sbjct: 8 HLSEKAGIPTMGGILIFFCVFISLVFWSNILNVYFCIMVFVMLGFAFLGFIDDFLKIKKK 67
Query: 81 -SVALKQSHKVLLSIMATF---PIVAYINRDYIVIIK-------PIHVGVLAVLVLWMYV 129
S LK K+ I+ +F I+ Y +++ +I I +G+ + +
Sbjct: 68 TSDGLKARFKIYGQIIFSFFSVGILYYFGGEHVSVIYFPFIKSFQIDLGLFYIPFGMFIL 127
Query: 130 VASTNLVNMLAGFNGLEVGMSSVI---LFFIAILG--------------EGSVRMLALIG 172
++++N N+ G +GL +G+S VI L IA L +GS ++ +G
Sbjct: 128 ISASNSFNLTDGLDGLAIGLSIVITGALIIIAYLTSRADFAAYLHIPNIKGSEELVIFLG 187
Query: 173 --LFASLGFLYWNKYPAKVFPGDTGTLSLGTLIGLLAILGKLEFPVAIM 219
L S GFL++N YPAK+ GDTG+L+LG ++G+ A++ K E +I+
Sbjct: 188 ALLGGSFGFLWFNAYPAKIMMGDTGSLALGAILGMAALILKSEILFSIL 236
>sp|P57314|MRAY_BUCAI PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE
(UDP-MURNAC-PENTAPEPTIDE PHOSPHOTRANSFERASE)
>gi|10038900|dbj|BAB12935.1| (AP001118)
phospho-N-acetylmuramoyl-pentapeptide-transferas e
[Buchnera sp. APS]
Length = 357
Score = 78.8 bits (191), Expect = 7e-14
Identities = 71/265 (26%), Positives = 126/265 (46%), Gaps = 52/265 (19%)
Query: 5 LLAFALSLALTPYIA---KLMKNAGIVGIDVHKVE--KVEVPEMGGLALLISISLVSLL- 58
L +F ++L + PY K ++ I+ + K K P MGG+ ++ SI ++L
Sbjct: 28 LTSFFINLYIGPYFIYYFKKLQTYQIIRNNGPKTHYSKKNTPTMGGIFIIFSILFSTILY 87
Query: 59 ---AKINGW-ILAVFLLMGLVGVIDDSVALKQSHKVLLSIMATF---PIVAYI------- 104
+ I W ++++ + GL+G IDD +K + L + + I+A+I
Sbjct: 88 CNLSNIYIWYVISILIGYGLIGFIDDYKKIKYKNSQGLKLKWKYFFLSIIAFIFICMIKI 147
Query: 105 -NRDYI--------VIIKPIHVGVLAVLVLWMYVVASTNLVNMLAGFNGLEV-------- 147
N+D I I + L + + + +V ++N VN+ G +GL +
Sbjct: 148 NNKDIISTELIIPFCIKNDFEINYLYIFLSYFVLVGTSNAVNLTDGLDGLAIMPVIFLTC 207
Query: 148 GMSSVILF-------------FIAILGEGSVRMLALIGLFASLGFLYWNKYPAKVFPGDT 194
G++ + LF ++ E ++ +A++G + LGFL++N YPAKVF GD
Sbjct: 208 GLTLISLFSDNINISHYLHVQYVKNSTELAILCMAIVG--SGLGFLWFNSYPAKVFMGDV 265
Query: 195 GTLSLGTLIGLLAILGKLEFPVAIM 219
G+L+LG +G +AIL E + IM
Sbjct: 266 GSLALGGSLGAIAILLHQELLLIIM 290
>pir||H83094 phospho-N-acetylmuramoyl-pentapeptide- transferase PA4415
[imported] - Pseudomonas aeruginosa (strain PAO1)
>gi|9950647|gb|AAG07803.1|AE004856_14 (AE004856)
phospho-N-acetylmuramoyl-pentapeptide-transferase
[Pseudomonas aeruginosa]
Length = 360
Score = 78.4 bits (190), Expect = 9e-14
Identities = 77/267 (28%), Positives = 124/267 (45%), Gaps = 56/267 (20%)
Query: 5 LLAFALSLALTPYIAKLMKNAGIV------GIDVHKVEKVEVPEMGGLALLISISLVSLL 58
L A +LSL L P++ + ++ I G H + K P MGG +L +I++ +LL
Sbjct: 31 LTALSLSLWLGPWMIRTLQIRQIGQAVRNDGPQSH-LSKKGTPTMGGALILTAIAISTLL 89
Query: 59 -AKING---WI-LAVFLLMGLVGVIDD--SVALKQSH------------------KVLLS 93
A ++ W+ L V LL G +G +DD V K S V L
Sbjct: 90 WADLSNRYVWVVLVVTLLFGAIGWVDDYRKVIEKNSRGLPSRWKYFWQSVFGIGAAVFLY 149
Query: 94 IMATFPIVAYINRDYIVIIKPIHVGVLAVLVLWMYVVASTNLVNMLAGFNGLEVGMSSVI 153
+ A PI + + ++ I +G+ V++ + +V S+N VN+ G +GL + + ++
Sbjct: 150 MTAETPIETTLIVPMLKSVE-IQLGIFFVVLTYFVIVGSSNAVNLTDGLDGLAIMPTVMV 208
Query: 154 LFFIAIL---------------------GEGSVRMLALIGLFASLGFLYWNKYPAKVFPG 192
+ I GE V AL+G A LGFL++N YPA+VF G
Sbjct: 209 AGALGIFCYLSGNVKFAEYLLIPNVPGAGELIVFCAALVG--AGLGFLWFNTYPAQVFMG 266
Query: 193 DTGTLSLGTLIGLLAILGKLEFPVAIM 219
D G L+LG +G +A++ + E + IM
Sbjct: 267 DVGALALGAALGTIAVIVRQEIVLFIM 293
>gb|AAG22121.1| (AY008276) phospho-N-acetylmuramoyl-pentapeptide translocase
[Pseudomonas aeruginosa]
Length = 360
Score = 78.4 bits (190), Expect = 9e-14
Identities = 77/267 (28%), Positives = 124/267 (45%), Gaps = 56/267 (20%)
Query: 5 LLAFALSLALTPYIAKLMKNAGIV------GIDVHKVEKVEVPEMGGLALLISISLVSLL 58
L A +LSL L P++ + ++ I G H + K P MGG +L +I++ +LL
Sbjct: 31 LTALSLSLWLGPWMIRTLQIPQIGQAVRNDGPQSH-LSKKGTPTMGGALILTAIAISTLL 89
Query: 59 -AKING---WI-LAVFLLMGLVGVIDD--SVALKQSH------------------KVLLS 93
A ++ W+ L V LL G +G +DD V K S V L
Sbjct: 90 WADLSNRYVWVVLVVTLLFGAIGWVDDYRKVIEKNSRGLPSRWKYFWQSVFGIGAAVFLY 149
Query: 94 IMATFPIVAYINRDYIVIIKPIHVGVLAVLVLWMYVVASTNLVNMLAGFNGLEVGMSSVI 153
+ A PI + + ++ I +G+ V++ + +V S+N VN+ G +GL + + ++
Sbjct: 150 MTAETPIETTLIVPMLKSVE-IQLGIFFVVLTYFVIVGSSNAVNLTDGLDGLAIMPTVMV 208
Query: 154 LFFIAIL---------------------GEGSVRMLALIGLFASLGFLYWNKYPAKVFPG 192
+ I GE V AL+G A LGFL++N YPA+VF G
Sbjct: 209 AGALGIFCYLSGNVKFAEYLLIPNVPGAGELIVFCAALVG--AGLGFLWFNTYPAQVFMG 266
Query: 193 DTGTLSLGTLIGLLAILGKLEFPVAIM 219
D G L+LG +G +A++ + E + IM
Sbjct: 267 DVGALALGAALGTIAVIVRQEIVLFIM 293
>sp|Q03521|MRAY_BACSU PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE
(UDP-MURNAC-PENTAPEPTIDE PHOSPHOTRANSFERASE)
>gi|477962|pir||C47691
phospho-N-acetylmuramoyl-pentapeptide-transferase (EC
2.7.8.13) mraY - Bacillus subtilis
>gi|40163|emb|CAA78768.1| (Z15056) mraY [Bacillus
subtilis] >gi|2633890|emb|CAB13392.1| (Z99111)
phospho-N-acetylmuramoyl-pentapeptide transferase
[Bacillus subtilis]
Length = 324
Score = 77.3 bits (187), Expect = 2e-13
Identities = 90/329 (27%), Positives = 155/329 (46%), Gaps = 60/329 (18%)
Query: 5 LLAFALSLALTPYIAKLMKNAGI--VGIDVHKVEKVEVPEMGGLALLISISLVSLL---- 58
L++ LS L P++ +L I G H+ +K P MGG+ +++SI + +++
Sbjct: 15 LISVLLSPILIPFLRRLKFGQSIREEGPKSHQ-KKSGTPTMGGVMIILSIIVTTIVMTQK 73
Query: 59 -AKING---WILAVFLLMGLVGVIDD--------SVALKQSHKVLLSIMATFPIVAYINR 106
++I+ +L V L GL+G +DD ++ L K++ I+ +V Y
Sbjct: 74 FSEISPEMVLLLFVTLGYGLLGFLDDYIKVVMKRNLGLTSKQKLIGQIIIA--VVFYAVY 131
Query: 107 DYIVIIKPIHVG----------VLAVLVLWMYVVASTNLVNMLAGFNGLEVGMSSVILFF 156
Y I + +LVL+M +V +N VN+ G +GL G +++
Sbjct: 132 HYYNFATDIRIPGTDLSFDLGWAYFILVLFM-LVGGSNAVNLTDGLDGLLSGTAAIAFGA 190
Query: 157 IAILG------EGSVRMLALIGLFASLGFLYWNKYPAKVFPGDTGTLSLGTLIGLLAILG 210
AIL + ++ +A++G A LGFL +N+ PAKVF GDTG+L+LG I +AIL
Sbjct: 191 FAILAWNQSQYDVAIFSVAVVG--AVLGFLVFNRDPAKVFMGDTGSLALGGAIVTIAILT 248
Query: 211 KLEFPVAI---MLIPHALDFVLKAKVRFK--GKQIGRTRVLEDGTLVPPPYKSFLGLLMR 265
KLE + I + + L +L+ + FK GK+I + L + +G
Sbjct: 249 KLEILLVIIGGVFVIETLSVILQV-ISFKTTGKRIFKMSPLHH-------HYELVG---- 296
Query: 266 IKPMKEWELVLASIAIEFFLGIVALLIQL 294
EW +V+ A L ++ + I++
Sbjct: 297 ---WSEWRVVVTFWAAGLLLAVLGIYIEV 322
>sp|Q9ZCW0|MRAY_RICPR PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE
(UDP-MURNAC-PENTAPEPTIDE PHOSPHOTRANSFERASE)
>gi|7434925|pir||E71664
phospho-n-acetylmuramoyl-pentapeptide- transferase
(mraY1) RP595 - Rickettsia prowazekii
>gi|3861139|emb|CAA15039.1| (AJ235272)
PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE- TRANSFERASE
(mraY1) [Rickettsia prowazekii]
Length = 361
Score = 77.3 bits (187), Expect = 2e-13
Identities = 69/266 (25%), Positives = 131/266 (48%), Gaps = 54/266 (20%)
Query: 5 LLAFALSLALTPYIAKLMKNAGIVGIDV-------HKVEKVEVPEMGGLALLISISLVSL 57
++ ++S P + K +++ G + HK K P MGG+ +++S L +L
Sbjct: 31 IITLSISFVTGPILIKFLRSLQKYGQPIRSDGPESHKT-KAGTPTMGGIMIILSSCLSTL 89
Query: 58 L-AKING---WI-LAVFLLMGLVGVIDDSVALKQSH--------KVLLS---IMATFPIV 101
L A + WI L F+ G++G +DD +K+++ K LL + + ++
Sbjct: 90 LLADLTNKYIWITLFGFISFGIIGFMDDYAKVKRNNHYGVRGKSKFLLQGIISLIIYVLL 149
Query: 102 AYINRDYIVIIKPIHVGVLAVLVLWMY-------VVASTNLVNMLAGFNGLEV------- 147
Y+++++ ++ L++ + + Y +V S+N VN+ G +GL
Sbjct: 150 EYLDKNFSHLLNVPFFKNLSLDLNYFYMVFAIFVIVGSSNAVNLTDGLDGLATVPIAFTA 209
Query: 148 GMSSVILFFIAIL--------------GEGSVRMLALIGLFASLGFLYWNKYPAKVFPGD 193
G ++I + + L GE +V L+G + LGFL++N PA+VF GD
Sbjct: 210 GSFALISYLVGNLIYANYLQLTYIPNTGELTVLCAGLVG--SCLGFLWFNAQPAEVFMGD 267
Query: 194 TGTLSLGTLIGLLAILGKLEFPVAIM 219
TG+LSLG ++G+++++ K E +AI+
Sbjct: 268 TGSLSLGGVLGIISVITKHEIVLAII 293
>gb|AAF53252.1| (AE003639) CG5287 gene product [Drosophila melanogaster]
Length = 379
Score = 76.9 bits (186), Expect = 3e-13
Identities = 71/268 (26%), Positives = 115/268 (42%), Gaps = 69/268 (25%)
Query: 7 AFALSLALTPYIAKLMKNAGIVGIDVHKVEKVEVPEMGGLAL----LISISL-------- 54
A+ +++ + P ++ A + G D+ K +K +VPE G+ + L+S+ L
Sbjct: 16 AYCMTVRMIPRFREMFIKANLFGNDLCKKDKPQVPESFGVLIGCVFLVSLFLFIPIPFAF 75
Query: 55 ----------------------VSLLAKINGWILAVFLLMGLVGVIDDSVALKQSHKVLL 92
V L+A + +FL G DD + L+ HK+LL
Sbjct: 76 DEAAATDAITGGKPDTFPHDKFVELIAALLSICCMIFL-----GFADDVLDLRWRHKLLL 130
Query: 93 SIMATFPI--VAYINRDYIVIIKP----------IHVGVLAVLVLWMYVVASTNLVNMLA 140
+AT P+ V Y+N + +I P +++G L + + M V TN +N+LA
Sbjct: 131 PTIATLPLLMVYYVNYNSTTVIMPNFARNLIGTSLNIGALYYVFMGMLAVFCTNAINILA 190
Query: 141 GFNGLEVGMSSVILFFIAILGEGSVRMLALIGLFASLGFLYWNKYPAKVFPGDTGTLSLG 200
G NGLEVG S +I GS+ + I L LG +VF GDT G
Sbjct: 191 GINGLEVGQSFII--------AGSILVFNAIELL--LGH--------QVFVGDTYCYFAG 232
Query: 201 TLIGLLAILGKLEFPVAIMLIPHALDFV 228
++ ILG + + +P L+F+
Sbjct: 233 MTFAVVGILGHFSKTLLLFFLPQILNFL 260
>dbj|BAA82114.1| (AB022909) RgpG [Streptococcus mutans]
Length = 388
Score = 76.1 bits (184), Expect = 5e-13
Identities = 66/231 (28%), Positives = 109/231 (46%), Gaps = 33/231 (14%)
Query: 11 SLALTPYIAKLMKNAGIV-GIDVHKVEKVEVPEMGGLALLISISLVSLL-------AKIN 62
SL LTP + G V + ++ KV +P GGLA++IS + +L +I
Sbjct: 21 SLVLTPLVRFFALRVGAVDNPNARRINKVPMPSAGGLAIIISFVIATLALMPMILKTQIG 80
Query: 63 G-----WILAVFL---LMGLVGVIDDSVALKQSHKVLLSIMATFPIVAYINRDYIVIIKP 114
G +IL V L ++ L G IDD L K L ++ ++ +I D+
Sbjct: 81 GKSYFEYILPVVLGALVIALTGFIDDVYELSPKIKFLGILLGA--VIIWIFTDFRFDSFK 138
Query: 115 IHVG--------VLAVLVLWMYVVASTNLVNMLAGFNGLEVGMSSVIL-------FFIAI 159
I G L+ + ++VVA TN VN++ G +GL G+S + L +F
Sbjct: 139 IPFGGPMLHFNPFLSFFLTILWVVAITNAVNLIDGLDGLVSGVSMISLTTMGLVSYFFLY 198
Query: 160 LGEGSVRMLALIGLFASLGFLYWNKYPAKVFPGDTGTLSLGTLIGLLAILG 210
+ + + + +FA GF +N +PA ++ GDTG L +G +I +L++ G
Sbjct: 199 DTDIFLTLTIFVLIFAIAGFFPYNYHPAIIYLGDTGALFIGFMISVLSLQG 249
>sp|P42881|GPT_SCHPO UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE
N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE (GPT) (G1PT)
(N-ACETYLGLUCOSAMINE-1-PHOSPHATE TRANSFERASE)
(GLCNAC-1-P TRANSFERASE) >gi|1076929|pir||S50222
UDP-N-acetylglucosamine--dolichyl-phosphate
N-acetylglucosaminephosphotransferase (EC 2.7.8.15) -
fission yeast (Schizosaccharomyces pombe)
>gi|7450079|pir||S71622
UDP-N-acetylglucosamine--dolichyl-phosphate
N-acetylglucosaminephosphotransferase (EC 2.7.8.15) -
fission yeast (Schizosaccharomyces pombe)
>gi|7492219|pir||T39480 N-acetylglucosamine-1-phosphate
transferase - fission yeast (Schizosaccharomyces pombe)
>gi|488561|gb|AAA92799.1| (U09454)
UDP-N-acetylglucosamine: dolichyl phosphate
N-acetylglucosamine-1-phosphate transferase
[Schizosaccharomyces pombe] >gi|3451462|emb|CAA20479.1|
(AL031349) udp-n-acetylglucosamine--dolichyl-phosphate
n-acetylglucosaminephosphotransferase
[Schizosaccharomyces pombe]
Length = 446
Score = 76.1 bits (184), Expect = 5e-13
Identities = 74/297 (24%), Positives = 126/297 (41%), Gaps = 68/297 (22%)
Query: 5 LLAFALSLALTPYIAKLMKNAGIVGIDVHKVEKVEVPE-MGGLALLI------------- 50
+LA+ + P + G G D++KVEK +PE MG ++ L+
Sbjct: 34 VLAYKATAMFIPRVGPSFIKRGFSGKDMNKVEKYVIPETMGAVSALVYFMCMIIFIPVLF 93
Query: 51 -------------SISLVSLLAK-------INGWILAVF--LLMGLVGVIDDSVALKQSH 88
S V+ +AK + ++ A+ L + L+G++DD ++ H
Sbjct: 94 YKYLVPNHNPNLPSDGSVAEVAKSQFPHDLLGAYLSALLSILSVSLLGILDDLFDIRWRH 153
Query: 89 KVLLSIMATFPIVAYINRDYIV-------IIKP------IHVGVLAVLVLWMYVVASTNL 135
K L +A P++ DY V I++P I++G L + + N
Sbjct: 154 KFFLPAIAAIPLLVVYYVDYGVTYVSVPSIVRPFLKRSLINLGFLYYFYMAAVAIFCPNS 213
Query: 136 VNMLAGFNGLEVGMSSVILFFIAI---------LGEGSVR--------MLALIGLFASLG 178
+N++AG NG+E G S V+ IA + ++R +L LIG+ A G
Sbjct: 214 INIIAGVNGVEAGQSLVLALVIACNDLFYVLSPKNKDALRAHLLSLYLVLPLIGVTA--G 271
Query: 179 FLYWNKYPAKVFPGDTGTLSLGTLIGLLAILGKLEFPVAIMLIPHALDFVLKAKVRF 235
L +N +P++VF GDT G ++ ++ ILG + + IP +F L F
Sbjct: 272 LLKYNWWPSRVFVGDTFCYFAGMVMAVVGILGHFSKTLMLFFIPQIFNFALSVPQLF 328
>pir||E81736 phospho-N-acetylmuramoyl-pentapeptide- transferase TC0138
[imported] - Chlamydia muridarum (strain Nigg)
>gi|7190175|gb|AAF39016.1| (AE002281)
phospho-N-acetylmuramoyl-pentapeptide-transferase
[Chlamydia muridarum]
Length = 335
Score = 75.3 bits (182), Expect = 8e-13
Identities = 63/227 (27%), Positives = 105/227 (45%), Gaps = 45/227 (19%)
Query: 32 VHKVEKVEVPEMGGLALLISISL-VSLLAKINGW----ILAVFLLMGLVGVIDDSVALKQ 86
+HK K +P GG+ ++S+ L + LL N W ++ LL G +G DD + K
Sbjct: 48 LHK-NKAHIPTAGGIIFVLSVVLSILLLLPCNLWSTWFLVGATLLWGALGWRDDQI--KN 104
Query: 87 SHKV--------------LLSIMATFPIVAYINRDYIVIIKPIHVGVLAVLVLWM----- 127
KV L+I PI+ ++ + P VG++++ W+
Sbjct: 105 KRKVGHGLSAKRKFFIQNCLAIGTVLPIMIAYGESFLCMHLPF-VGIVSLPHCWLGYLFS 163
Query: 128 ------YVVASTNLVNMLAGFNGLEVGMSSVILFFIAILGEG---------SVRMLALIG 172
+V ++N VN+ G +GL G + + I+ V + L G
Sbjct: 164 FSIAVLAIVGTSNSVNLTDGLDGLAAGSMVIACLGMLIVTFAYGAPWAFISGVLLATLAG 223
Query: 173 LFASLGFLYWNKYPAKVFPGDTGTLSLGTLIGLLAILGKLEFPVAIM 219
+ LGFLY+N+ PA++F GDTG+L LG ++G+ A+L + EF + M
Sbjct: 224 --SCLGFLYYNRSPARIFMGDTGSLFLGGMLGICAVLLRAEFMLLFM 268
>pir||H82081 phospho-N-acetylmuramoyl-pentapeptide- transferase VC2404
[imported] - Vibrio cholerae (group O1 strain N16961)
>gi|9656977|gb|AAF95547.1| (AE004310)
phospho-N-acetylmuramoyl-pentapeptide-transferase
[Vibrio cholerae]
Length = 360
Score = 74.9 bits (181), Expect = 1e-12
Identities = 78/294 (26%), Positives = 139/294 (46%), Gaps = 60/294 (20%)
Query: 5 LLAFALSLALTPYIAKLMKNAGI------VGIDVHKVEKVEVPEMGGLALLISISLVSLL 58
L A +SL + P + K ++ I G + H K P MGG+ +L +I++ LL
Sbjct: 31 LTALGISLWMGPRMIKRLQMLQIGQVVRNEGPESH-FSKRGTPTMGGVMILAAITITVLL 89
Query: 59 -AKING---W-ILAVFLLMGLVGVIDD--SVALKQSHKVL----------LSIMATFPIV 101
A + W +LAV L G VG +DD V K + ++ ++++ F +
Sbjct: 90 WADLTNPYVWAVLAVLLGYGAVGFVDDYRKVVRKNTDGLIARWKYFWQSAIALVVAFALY 149
Query: 102 AY-----INRDYIVIIKPI--HVGVLAVLVLWMYVVASTNLVNMLAGFNGLEVGMSSVIL 154
A+ + + K + +G++ +++ + +V ++N VN+ G +GL + M +V++
Sbjct: 150 AHGQDTAATQLVVPFFKDVMPQLGLMYIVLTYFVIVGTSNAVNLTDGLDGLAI-MPTVLV 208
Query: 155 F----------------------FIAILGEGSVRMLALIGLFASLGFLYWNKYPAKVFPG 192
+I E V A++G A LGFL++N YPA+VF G
Sbjct: 209 AAGFAAIAWATGNVNFANYLHIPYIPHSSELVVVCTAMVG--AGLGFLWFNTYPAQVFMG 266
Query: 193 DTGTLSLGTLIGLLAILGKLEFPVAIM---LIPHALDFVLK-AKVRFKGKQIGR 242
D G L+LG +G +A+L + EF + IM + L +L+ + +G++I R
Sbjct: 267 DVGALALGGALGTIAVLVRQEFVLVIMGGVFVMETLSVILQVGSYKLRGQRIFR 320
>sp|O84762|MRAY_CHLTR PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE
(UDP-MURNAC-PENTAPEPTIDE PHOSPHOTRANSFERASE)
>gi|7434931|pir||D71474 probable muramoyl-pentapeptide
transferase - Chlamydia trachomatis (serotype D, strain
UW3/Cx) >gi|3329219|gb|AAC68352.1| (AE001348)
Muramoyl-Pentapeptide Transferase [Chlamydia
trachomatis]
Length = 336
Score = 74.5 bits (180), Expect = 1e-12
Identities = 64/223 (28%), Positives = 99/223 (43%), Gaps = 35/223 (15%)
Query: 31 DVHKVEKVEVPEMGGLALLI-SISLVSLLAKINGW----ILAVFLLMGLVGVIDDSV--- 82
++HK +K +P GG+ + S+ V LL I W + LL G +G DD +
Sbjct: 48 ELHK-DKAYIPTAGGIVFVFASVLAVLLLFPIQLWSTWFCIGTILLWGALGWCDDQIKNR 106
Query: 83 -----ALKQSHKVLLSIMATFPIVAYINRDYIVIIKPIHVGVLAVLVL----WMY----- 128
L HK L+ +V I Y H+ L ++ L W Y
Sbjct: 107 RRVGHGLSAKHKFLIQNCLAAGVVLPIMFAYKESFLSFHLPFLGIVSLPHHWWSYLLSFA 166
Query: 129 -----VVASTNLVNMLAGFNGLEVGMSSVILFFIAILG--EGSVRMLALIGLFASL---- 177
+V ++N VN+ G +GL G + + ++ G+ L A+L
Sbjct: 167 IATLAIVGTSNSVNLTDGLDGLAAGAMVIACLGMLVVACTNGAPWAFICCVLLATLAGSC 226
Query: 178 -GFLYWNKYPAKVFPGDTGTLSLGTLIGLLAILGKLEFPVAIM 219
GFL +NK PA+VF GDTG+L LG ++G+ A+L + EF + M
Sbjct: 227 LGFLRYNKSPARVFMGDTGSLFLGAMLGMCAVLLRAEFLLLFM 269
>emb|CAB60399.1| (AL117207) contains similarity to Pfam domain: PF00953 (Glycosyl
transferase), Score=203.7, E-value=9.3e-58, N=1
[Caenorhabditis elegans]
Length = 362
Score = 74.5 bits (180), Expect = 1e-12
Identities = 60/207 (28%), Positives = 98/207 (46%), Gaps = 37/207 (17%)
Query: 57 LLAKINGWILAVFLLMGLVGVIDDSVALKQSHKVLLSIMATFPI--VAYINRDYIVIIKP 114
LLA ++G I + L+G DD + LK HK+L +++ P+ V Y++ + +I P
Sbjct: 35 LLALLSGLISISTAI--LLGFADDMLDLKWRHKLLFPTLSSLPLLMVYYVSGNSTTVIVP 92
Query: 115 ----------------IHVGVLAVLVLWMYVVASTNLVNMLAGFNGLEVGMS-----SVI 153
I++ + + + M +V TN +N+LAG NGLE G S SV
Sbjct: 93 TIVRHLVQPIVLLPVTINISFIYYIFMGMVIVFCTNAINILAGINGLESGQSLVISASVC 152
Query: 154 LF-FIAILGEGSVRMLAL----IGLFASLGF-------LYWNKYPAKVFPGDTGTLSLGT 201
LF F+ I + I L+ L F Y+NKYP++VF GDT G
Sbjct: 153 LFNFVQIFRFSAENSTGFWHHTISLYFLLPFTACTAILFYFNKYPSRVFVGDTFCYWSGM 212
Query: 202 LIGLLAILGKLEFPVAIMLIPHALDFV 228
+ +++ILG + + +P ++F+
Sbjct: 213 TLAVVSILGHFSKTLMLFFVPQIINFL 239
>gi|6319720 UDP-N-acetyl-glucosamine-1-P transferase (GPT); Alg7p
[Saccharomyces cerevisiae]
>gi|121565|sp|P07286|GPT_YEAST
UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE
N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE (GPT) (G1PT)
(N-ACETYLGLUCOSAMINE-1-PHOSPHATE TRANSFERASE)
(GLCNAC-1-P TRANSFERASE) (TUNICAMYCIN RESISTANCE PROTEIN
1) >gi|83402|pir||A27522
UDP-N-acetylglucosamine--dolichyl-phosphate
N-acetylglucosaminephosphotransferase (EC 2.7.8.15) -
yeast (Saccharomyces cerevisiae)
>gi|4685|emb|CAA68324.1| (Y00126) ORF (AA 1-448)
[Saccharomyces cerevisiae] >gi|536653|emb|CAA85206.1|
(Z36112) ORF YBR243c [Saccharomyces cerevisiae]
Length = 448
Score = 74.1 bits (179), Expect = 2e-12
Identities = 78/308 (25%), Positives = 130/308 (41%), Gaps = 79/308 (25%)
Query: 60 KINGWILAVFLLMG--LVGVIDDSVALKQSHKVLLSIMATFPI--VAYINRDYIVIIKPI 115
K++ ++ A+ L L+G+ DD L+ HK L +A P+ V Y++ ++ P
Sbjct: 125 KLSEYLSAILCLESTVLLGIADDLFDLRWRHKFFLPAIAAIPLLMVYYVDFGVTHVLIPG 184
Query: 116 HVG-----VLAVLVLWMYVVAST------NLVNMLAGFNGLEVGMSSVILFFIAILGE-- 162
+ L LW YV ++ N +N+LAG NGLEVG ++L +A+L +
Sbjct: 185 FMERWLKKTSVDLGLWYYVYMASMAIFCPNSINILAGVNGLEVGQC-IVLAILALLNDLL 243
Query: 163 ---------------GSVRMLALIGLFASLGFLYWNKYPAKVFPGDTGTLSLGTLIGLLA 207
+V ++ +G+ SL WN++PA VF GDT G + ++
Sbjct: 244 YFSMGPLATRDSHRFSAVLIIPFLGV--SLALWKWNRWPATVFVGDTYCYFAGMVFAVVG 301
Query: 208 ILGKLEFPVAIMLIPHALDFVLKAKVRFKGKQIGRTRV----LEDGTLVP--------PP 255
ILG + ++ IP ++F+ FK R R+ +DG + P PP
Sbjct: 302 ILGHFSKTMLLLFIPQIVNFIYSCPQLFKLVPCPRHRLPKFNEKDGLMYPSRANLKEEPP 361
Query: 256 ---YKSFLGLLMRIK-----------------------------PMKEWELVLASIAIEF 283
+K L LL + PM+E +L + ++F
Sbjct: 362 KSIFKPILKLLYCLHLIDLEFDENNEIISTSNMTLINLTLVWFGPMREDKLCNTILKLQF 421
Query: 284 FLGIVALL 291
+GI+ALL
Sbjct: 422 CIGILALL 429
>pir||G81387 phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13)
Cj0433c [imported] - Campylobacter jejuni (strain NCTC
11168) >gi|6967907|emb|CAB74269.1| (AL139075)
phospho-N-acetylmuramoyl-pentapeptide- transferase
[Campylobacter jejuni]
Length = 353
Score = 73.7 bits (178), Expect = 2e-12
Identities = 76/244 (31%), Positives = 116/244 (47%), Gaps = 51/244 (20%)
Query: 31 DVHKVEKVEVPEMGGLALLISISLVSLLAKINGWILAV-----FLLMGLVGVIDD--SVA 83
+ HK K P MGGL + S + SL I A+ +L L+G+IDD V
Sbjct: 57 ETHKT-KCHTPTMGGLIFISSAVIASLFCIKFDNIFAISALLCLILFCLIGLIDDLGKVL 115
Query: 84 LKQSH-------KVLLSIMATFPIVA--YINRD-----YIVIIK-PIHVGVLAVLVLWMY 128
K +H K+L I+A + Y + + +I K P+ + + W+
Sbjct: 116 KKDNHSGLSPRMKLLAQIIAGLICILPLYFSSELSTELFIPFYKHPLFDMEIFAIAFWIL 175
Query: 129 V-VASTNLVNMLAGFNGLEV-----GMSSVILFF----------------IAILGEGSVR 166
V ++S+N VN+ G +GL +S++ +F I LGE +
Sbjct: 176 VLISSSNAVNLTDGLDGLATVPGIFSLSTLGIFLYLSGNLNYSEYLLLPKIQGLGEVVII 235
Query: 167 MLALIGLFASLGFLYWNKYPAKVFPGDTGTLSLGTLIGLLAILGKLEFPVAIMLIPHALD 226
ALIG A +GFL++N YPA+VF GD+G+L+LG IG LA++ K E I+L+
Sbjct: 236 CAALIG--ALMGFLWYNCYPAQVFMGDSGSLALGGFIGFLAVISKNE----ILLLLIGFV 289
Query: 227 FVLK 230
FVL+
Sbjct: 290 FVLE 293
>sp|P45062|MRAY_HAEIN PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE
(UDP-MURNAC-PENTAPEPTIDE PHOSPHOTRANSFERASE)
>gi|1075141|pir||A64185
phospho-N-acetylmuramoyl-pentapeptide-transferase (EC
2.7.8.13) - Haemophilus influenzae (strain Rd KW20)
>gi|1574690|gb|AAC22790.1| (U32793)
phospho-N-acetylmuramoyl-pentapeptide-transferase E
(mraY) [Haemophilus influenzae Rd]
Length = 360
Score = 73.4 bits (177), Expect = 3e-12
Identities = 68/242 (28%), Positives = 115/242 (47%), Gaps = 50/242 (20%)
Query: 37 KVEVPEMGGLALLISISLVSLL----AKINGWI-LAVFLLMGLVGVIDD--SVALKQSHK 89
K P MGG+ +L SI + +LL A W+ L V G +G +DD + K +
Sbjct: 68 KKGTPTMGGVMILFSIGVSTLLWANLANPYIWVCLFVLFGYGAIGFVDDFRKITRKNTDG 127
Query: 90 VL-------LSIMATFPIV--------AYINRDYIVIIKPI--HVGVLAVLVLWMYVVAS 132
++ +S++A I+ R I K I +G+ +++ + +V +
Sbjct: 128 LIARWKYFWMSVVALVAILWLYWLGHDTDATRLVIPFFKDIMPQLGLFYIVLSYFVIVGT 187
Query: 133 TNLVNMLAGFNGLEVGMSSVILFFIAILG---------------------EGSVRMLALI 171
N VN+ G +GL + ++++ A++ E V A++
Sbjct: 188 GNAVNLTDGLDGLAIMPTALVAGAFALIAWATGNVNFAEYLHIPYIKYSSEVVVFCTAIV 247
Query: 172 GLFASLGFLYWNKYPAKVFPGDTGTLSLGTLIGLLAILGKLEFPVAIM---LIPHALDFV 228
G ASLGFL++N YPA+VF GD G+L+LG +G++AIL + EF + IM + AL +
Sbjct: 248 G--ASLGFLWFNTYPAQVFMGDVGSLALGGALGVVAILVRQEFLLVIMGGVFVVEALSVI 305
Query: 229 LK 230
L+
Sbjct: 306 LQ 307
>pir||E81200 phospho-N-acetylmuramoyl-pentapeptide- transferase NMB0418
[imported] - Neisseria meningitidis (group B strain
MD58) >gi|7225641|gb|AAF40856.1| (AE002398)
phospho-N-acetylmuramoyl-pentapeptide-transferase
[Neisseria meningitidis MC58]
Length = 360
Score = 73.4 bits (177), Expect = 3e-12
Identities = 76/264 (28%), Positives = 120/264 (44%), Gaps = 49/264 (18%)
Query: 5 LLAFALSLALTPYIAK---LMKNAGIVGIDVHKVEKVE--VPEMGGLALLISISLVSLL- 58
L A A SL P+ + +K V D + V+ P MGG +L +I++ +LL
Sbjct: 30 LTALAFSLMFGPWTIRRLTALKCGQAVRTDGPQTHLVKNGTPTMGGSLILTAITVSTLLW 89
Query: 59 ---AKINGWIL-AVFLLMGLVGVIDD----------SVALK-----QSHKVLLSIMATFP 99
A WIL V L G +G DD V+ K QS +++ +A F
Sbjct: 90 GNWANPYIWILLGVLLATGALGFYDDWRKVVYKDPNGVSAKFKMVWQSSVAIIASLALFY 149
Query: 100 IVAYINRDYIVI--IKPIHV--GVLAVLVL-WMYVVASTNLVNMLAGFNGLEVGMSSVIL 154
+ A + +++ K I + GV+ LVL ++ +V ++N VN+ G +GL ++
Sbjct: 150 LAANSANNILIVPFFKQIALPLGVVGFLVLSYLTIVGTSNAVNLTDGLDGLATFPVVLVA 209
Query: 155 FFIAIL-------------------GEGSVRMLALIGLFASLGFLYWNKYPAKVFPGDTG 195
+AI G V + A LGFL++N YPA+VF GD G
Sbjct: 210 AGLAIFAYASGHSQFAQYLQLPYVAGANEVVIFCTAMCGACLGFLWFNAYPAQVFMGDVG 269
Query: 196 TLSLGTLIGLLAILGKLEFPVAIM 219
L+LG +G +A++ + EF + IM
Sbjct: 270 ALALGAALGTVAVIVRQEFVLVIM 293
>sp|Q9Z706|MRAY_CHLPN PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE
(UDP-MURNAC-PENTAPEPTIDE PHOSPHOTRANSFERASE)
>gi|7434930|pir||G72021 muramoyl-pentapeptide
transferase - Chlamydophila pneumoniae (strain CWL029)
>gi|4377220|gb|AAD19038.1| (AE001670)
Muramoyl-Pentapeptide Transferase [Chlamydophila
pneumoniae CWL029]
Length = 349
Score = 73.0 bits (176), Expect = 4e-12
Identities = 70/223 (31%), Positives = 111/223 (49%), Gaps = 46/223 (20%)
Query: 32 VHKVEKVEVPEMGGLALLISISLVSLLA-----KINGWILAVFLLMGL-VGVIDDSV--- 82
+HK +K EVP GG+ L IS+ + SLL K + W + L +G DD +
Sbjct: 59 LHK-DKAEVPTGGGVLLFISL-IASLLVWLPWGKFSTWFFIILLTCYAGLGWYDDRIKIK 116
Query: 83 -----ALKQSHKVLLSI-MATFPIVA----YINRDYIVIIK-PIHVGVLAVLVLWM---- 127
LK HK ++ I +A F ++A Y + + + +K P G+L+ L W+
Sbjct: 117 RKQGHGLKAKHKFMVQIAIAAFTLIALPYIYGSTEPLWTLKIPFMEGMLS-LPFWLGKVF 175
Query: 128 -------YVVASTNLVNMLAGFNGLEVG-MSSVILFFIAILGEGSVR---------MLAL 170
++ ++N VN+ G +GL G MS L FI + S + AL
Sbjct: 176 CLGLALVAIIGTSNAVNLTDGLDGLAAGTMSFAALGFIFVALRSSTIPIAQDVAYVLAAL 235
Query: 171 IGLFASLGFLYWNKYPAKVFPGDTGTLSLGTLIGLLAILGKLE 213
+G A +GFL++N +PA++F GDTG+L LG L+G A++ + E
Sbjct: 236 VG--ACIGFLWYNGFPAQLFMGDTGSLLLGGLLGSCAVMLRAE 276
>pir||A81519 phospho-N-acetylmuramoyl-pentapeptide- transferase CP0966
[imported] - Chlamydophila pneumoniae (strain AR39)
>gi|7189878|gb|AAF38746.1| (AE002254)
phospho-N-acetylmuramoyl-pentapeptide-transferase
[Chlamydophila pneumoniae AR39]
>gi|8979274|dbj|BAA99108.1| (AP002548)
muramoyl-pentapeptide transferase [Chlamydophila
pneumoniae J138]
Length = 349
Score = 73.0 bits (176), Expect = 4e-12
Identities = 70/223 (31%), Positives = 111/223 (49%), Gaps = 46/223 (20%)
Query: 32 VHKVEKVEVPEMGGLALLISISLVSLLA-----KINGWILAVFLLMGL-VGVIDDSV--- 82
+HK +K EVP GG+ L IS+ + SLL K + W + L +G DD +
Sbjct: 59 LHK-DKAEVPTGGGVLLFISL-IASLLVWLPWGKFSTWFFIILLTCYAGLGWYDDRIKIK 116
Query: 83 -----ALKQSHKVLLSI-MATFPIVA----YINRDYIVIIK-PIHVGVLAVLVLWM---- 127
LK HK ++ I +A F ++A Y + + + +K P G+L+ L W+
Sbjct: 117 RKQGHGLKAKHKFMVQIAIAAFTLIALPYIYGSTEPLWTLKIPFMEGMLS-LPFWLGKVF 175
Query: 128 -------YVVASTNLVNMLAGFNGLEVG-MSSVILFFIAILGEGSVR---------MLAL 170
++ ++N VN+ G +GL G MS L FI + S + AL
Sbjct: 176 CLGLALVAIIGTSNAVNLTDGLDGLAAGTMSFAALGFIFVALRSSTIPIAQDVAYVLAAL 235
Query: 171 IGLFASLGFLYWNKYPAKVFPGDTGTLSLGTLIGLLAILGKLE 213
+G A +GFL++N +PA++F GDTG+L LG L+G A++ + E
Sbjct: 236 VG--ACIGFLWYNGFPAQLFMGDTGSLLLGGLLGSCAVMLRAE 276
>pir||F81777 phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13)
NMA2066 [imported] - Neisseria meningitidis (group A
strain Z2491) >gi|7380694|emb|CAB85284.1| (AL162758)
phopho-N-acetylmuramoyl-pentapeptide-transferase
[Neisseria meningitidis Z2491]
Length = 360
Score = 72.6 bits (175), Expect = 5e-12
Identities = 76/264 (28%), Positives = 120/264 (44%), Gaps = 49/264 (18%)
Query: 5 LLAFALSLALTPYIAK---LMKNAGIVGIDVHKVEKVE--VPEMGGLALLISISLVSLL- 58
L A A SL P+ + +K V D + V+ P MGG +L +I++ +LL
Sbjct: 30 LTALAFSLMFGPWTIRRLTALKCGQAVRTDGPQTHLVKNGTPTMGGSLILTAITVSTLLW 89
Query: 59 ---AKINGWIL-AVFLLMGLVGVIDD----------SVALK-----QSHKVLLSIMATFP 99
A WIL V L G +G DD V+ K QS +++ +A F
Sbjct: 90 GNWANPYIWILLGVLLATGALGFYDDWRKVVYKDPNGVSAKFKMVWQSSVAIIAGLALFY 149
Query: 100 IVAYINRDYIVI--IKPIHV--GVLAVLVL-WMYVVASTNLVNMLAGFNGLEVGMSSVIL 154
+ A + +++ K I + GV+ LVL ++ +V ++N VN+ G +GL ++
Sbjct: 150 LAANSANNILIVPFFKQIALPLGVVGFLVLSYLTIVGTSNAVNLTDGLDGLATFPVVLVA 209
Query: 155 FFIAIL-------------------GEGSVRMLALIGLFASLGFLYWNKYPAKVFPGDTG 195
+AI G V + A LGFL++N YPA+VF GD G
Sbjct: 210 AGLAIFAYASGHSQFAQYLQLPYVAGANEVVIFCTAMCGACLGFLWFNAYPAQVFMGDVG 269
Query: 196 TLSLGTLIGLLAILGKLEFPVAIM 219
L+LG +G +A++ + EF + IM
Sbjct: 270 ALALGAALGTVAVIVRQEFVLVIM 293
>gb|AAC35916.1| (AF071085) Orfde3 [Enterococcus faecalis]
Length = 330
Score = 71.0 bits (171), Expect = 2e-11
Identities = 58/189 (30%), Positives = 99/189 (51%), Gaps = 18/189 (9%)
Query: 40 VPEMGGLALLISISLVSLLAKIN----GWILAVFLLMGLV---GVIDDSVALKQSHKVLL 92
+P GGLA+ I+ + LL + +I + L G+V G+IDD + K +
Sbjct: 1 MPTAGGLAIYIAFASSCLLIFRSIIPQDYIWPIILAGGMVVLTGLIDDIKEITPMKKTIG 60
Query: 93 SIMATFPI--VAYINRDYIV--IIKPIHVGVLAVLVLWMYVVASTNLVNMLAGFNGLEVG 148
++A I VA I D++ ++ I + ++ + ++++A TN VN++ G +GL G
Sbjct: 61 ILLAALVIYFVAGIRIDFVTLPVVGMIDLRWFSLPLTLLWILAITNAVNLIDGLDGLASG 120
Query: 149 MSSVILFFIAILGEGSVRM------LALIGLFASL-GFLYWNKYPAKVFPGDTGTLSLGT 201
+S + L I I G + + + L AS+ GF +N YPAK+F GDTG L LG
Sbjct: 121 VSIIGLTTIGITGYFFLHAKTVYIPIVIFILVASIAGFFPYNFYPAKIFLGDTGALFLGF 180
Query: 202 LIGLLAILG 210
+I ++++ G
Sbjct: 181 MIAVMSLQG 189
>pir||B82763 phospho-N-acetylmuramoyl-pentapeptide- transferase XF0795
[imported] - Xylella fastidiosa (strain 9a5c)
>gi|9105691|gb|AAF83605.1|AE003919_16 (AE003919)
phospho-N-acetylmuramoyl-pentapeptide-transferase
[Xylella fastidiosa]
Length = 361
Score = 69.5 bits (167), Expect = 5e-11
Identities = 60/229 (26%), Positives = 102/229 (44%), Gaps = 48/229 (20%)
Query: 37 KVEVPEMGGLALLISISLVSLL-----AKINGWILAVFLLMGLVGVIDDSV--------A 83
K P MGG +L++++L LL + +L V L G +G DD +
Sbjct: 68 KAGTPTMGGSLILMTVTLSVLLWGDLRNRYVWLVLVVMLAFGAIGWYDDWIKLARRDPNG 127
Query: 84 LKQSHKVLLSIMATFPIVA----YINRD-------YIVIIKPIHVGVLA---VLVLWMYV 129
LK K LL + F + A Y D YI + K I + + + V + + ++
Sbjct: 128 LKSRWKYLLQ--SIFGLAAGLFLYFTADVPAAVTFYIPMFKSIALPLTSISFVAITYFWI 185
Query: 130 VASTNLVNMLAGFNGLEVGMSSVILFFIAIL-------------------GEGSVRMLAL 170
V +N VN+ G +GL + + ++ + + G G + ++
Sbjct: 186 VGFSNAVNLTDGLDGLAIMPTVLVACALGVFAYASGNTLFSSYLKIPTIPGAGDLIIICA 245
Query: 171 IGLFASLGFLYWNKYPAKVFPGDTGTLSLGTLIGLLAILGKLEFPVAIM 219
A LGFL++N YPA VF GD G L+LG ++G +A++ + E + +M
Sbjct: 246 AIAGAGLGFLWFNAYPAMVFMGDIGALALGAVLGTIAVIVRQELVLVVM 294
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.329 0.146 0.422
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98183076
Number of Sequences: 2977
Number of extensions: 3817740
Number of successful extensions: 11551
Number of sequences better than 1.0e-10: 45
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 41
Number of HSP's that attempted gapping in prelim test: 11448
Number of HSP's gapped (non-prelim): 48
length of query: 295
length of database: 189,106,746
effective HSP length: 53
effective length of query: 242
effective length of database: 157,386,935
effective search space: 38087638270
effective search space used: 38087638270
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.7 bits)
S2: 165 (68.7 bits)