BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1300 (apeH) DE:ACYLAMINO-ACID-RELEASING ENZYME (EC 3.4.19.1)
(ACYL-PEPTIDE HYDROLASE) (APH) (ACYLAMINOACYL-PEPTIDASE)
(631 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||H75007 probable acylaminoacyl-peptidase (EC 3.4.19.1) PAB13... 1300 0.0
pir||C71137 hypothetical protein PH0863 - Pyrococcus horikoshii ... 1078 0.0
pir||F72568 probable acylamino-acid-releasing enzyme APE1832 - A... 433 e-120
sp|P39839|YUXL_BACSU PROBABLE PEPTIDASE YUXL >gi|7475770|pir||E7... 415 e-115
pir||F72455 probable acylamino-acid-releasing enzyme APE2290 - A... 339 6e-92
pir||E75057 peptidase PAB1418 - Pyrococcus abyssi (strain Orsay)... 317 2e-85
pir||E75551 probable acyl-peptide hydrolase - Deinococcus radiod... 317 3e-85
pir||F71174 hypothetical protein PH0594 - Pyrococcus horikoshii ... 316 4e-85
gb|AAK42808.1| Acylaminoacyl-peptidase, putative (apeH-3) [Sulfo... 262 1e-68
gb|AAG20414.1| (AE005114) acylaminoacyl-peptidase; YuxL [Halobac... 245 8e-64
pir||B82580 alanyl dipeptidyl peptidase XF2260 [imported] - Xyle... 151 3e-35
emb|CAB88242.1| (AL353012) putative dipeptidyl peptidase; possib... 142 1e-32
gb|AAF20265.1| (AF059279) dipeptidyl-peptidase [Entamoeba dispar] 132 1e-29
gb|AAF20264.1|AF059278_1 (AF059278) dipeptidyl-peptidase [Entamo... 129 1e-28
emb|CAC11802.1| (AL445065) hypothetical protein [Thermoplasma ac... 129 1e-28
gb|AAD41777.1|AF125190_1 (AF125190) alanyl dipeptidyl peptidase ... 124 2e-27
gb|AAD52012.1|AF082514_1 (AF082514) Tri r 4 allergen [Trichophyt... 121 2e-26
pir||T09631 probable acylaminoacyl-peptidase (EC 3.4.19.1) - Asp... 120 5e-26
gi|6978513 n-acylaminoacyl-peptide hydrolase [Rattus norvegicus]... 118 2e-25
pir||JU0132 acylaminoacyl-peptidase (EC 3.4.19.1) [validated] - ... 116 6e-25
sp|P19205|ACPH_PIG ACYLAMINO-ACID-RELEASING ENZYME (ACYL-PEPTIDE... 116 6e-25
emb|CAA33040.1| (X14915) acyl-peptide hydrolase [Rattus norvegicus] 115 2e-24
gi|9951917 N-acylaminoacyl-peptide hydrolase; oxidized protein h... 114 3e-24
gb|AAF37321.1|AF141383_1 (AF141383) oxidized protein hydrolase [... 114 3e-24
gi|11431488 N-acylaminoacyl-peptide hydrolase [Homo sapiens] 114 3e-24
gb|AAC46184.1| (AF026511) dipeptidyl peptidase IV [Porphyromonas... 109 7e-23
gb|AAC35353.1| (AF083393) outer membrane protein adhesin [Capnoc... 109 9e-23
pir||H72474 probable acylamino-acid-releasing enzyme APE2441 - A... 106 6e-22
dbj|BAA28265.1| (AB008194) DPP IV [Porphyromonas gingivalis] 106 8e-22
gb|AAK42319.1| Acylaminoacyl-peptidase, putative (apeH-2) [Sulfo... 104 4e-21
pir||S74053 probable acylaminoacyl-peptidase (EC 3.4.19.1) - Sul... 104 4e-21
gb|AAF56356.1| (AE003749) CG3744 gene product [alt 1] [Drosophil... 99 2e-19
gb|AAF56357.1| (AE003749) CG3744 gene product [alt 2] [Drosophil... 99 2e-19
gb|AAG29766.1|AF221634_1 (AF221634) dipeptidyl peptidase 8 [Homo... 96 9e-19
pir||S66261 X-Pro dipeptidyl-peptidase (EC 3.4.14.11) - Flavobac... 93 1e-17
pir||JC5142 X-Pro dipeptidyl-peptidase (EC 3.4.14.11) - Xanthomo... 91 4e-17
gi|6324793 dipeptidyl aminopeptidase; Ste13p [Saccharomyces cere... 89 2e-16
pir||S75772 hypothetical protein slr0825 - Synechocystis sp. (st... 85 2e-15
pir||T33751 hypothetical protein R11E3.8 - Caenorhabditis elegan... 84 4e-15
gb|AAK41653.1| Acylaminoacyl-peptidase, putative (apeH-1) [Sulfo... 83 9e-15
pir||T15945 hypothetical protein F01F1.5 - Caenorhabditis elegan... 80 8e-14
gb|AAG18962.1| (AE004997) Vng0409c [Halobacterium sp. NRC-1] 80 8e-14
gb|AAG29769.1|AF221637_1 (AF221637) dipeptidyl peptidase 8 [Homo... 79 1e-13
emb|CAB39035.2| (AL034559) putative acylaminoacyl-peptidase [Pla... 78 4e-13
sp|P34422|YL31_CAEEL HYPOTHETICAL 86.0 KDA PROTEIN F44B9.1 IN CH... 77 5e-13
gb|AAF52407.2| (AE003614) CG11319 gene product [Drosophila melan... 77 5e-13
pir||T32919 hypothetical protein K02F2.1 - Caenorhabditis elegan... 75 2e-12
pir||T19514 hypothetical protein C27C12.7 - Caenorhabditis elega... 75 2e-12
gb|AAC33801.1| (AC005594) R26984_1 [Homo sapiens] 75 3e-12
pir||D72636 probable acylamino-acid-releasing enzyme APE1547 - A... 74 4e-12
pir||G82543 conserved hypothetical protein XF2551 [imported] - X... 74 4e-12
pir||F82858 dipeptidyl-peptidase XF0015 [imported] - Xylella fas... 74 6e-12
pir||A39914 dipeptidyl-peptidase IV (EC 3.4.14.5), membrane-boun... 73 1e-11
pir||F83397 probable peptidase PA1990 [imported] - Pseudomonas a... 72 2e-11
gi|6978773 dipeptidyl peptidase 4 [Rattus norvegicus] >gi|118905... 72 2e-11
pir||T35378 probable peptide hydrolase - Streptomyces coelicolor... 71 3e-11
>pir||H75007 probable acylaminoacyl-peptidase (EC 3.4.19.1) PAB1300 [similarity]
- Pyrococcus abyssi (strain Orsay)
>gi|5459016|emb|CAB50502.1| (AJ248288)
ACYLAMINO-ACID-RELEASING ENZYME (EC 3.4.19.1)
(ACYL-PEPTIDE HYDROLASE) (APH) (ACYLAMINOACYL-PEPTIDASE)
[Pyrococcus abyssi]
Length = 631
Score = 1300 bits (3328), Expect = 0.0
Identities = 631/631 (100%), Positives = 631/631 (100%)
Query: 1 MMKKISEKDIEKFKLVGNLDASGKKVVFQVTEISIKENDYFSSIYLYDGRKVRRFTFGRK 60
MMKKISEKDIEKFKLVGNLDASGKKVVFQVTEISIKENDYFSSIYLYDGRKVRRFTFGRK
Sbjct: 1 MMKKISEKDIEKFKLVGNLDASGKKVVFQVTEISIKENDYFSSIYLYDGRKVRRFTFGRK 60
Query: 61 DANPRFSPDGRLIAFTSKRSKEGRESELYLMPVDGGEARLLAKFKYGIKDLRFSEDGKEI 120
DANPRFSPDGRLIAFTSKRSKEGRESELYLMPVDGGEARLLAKFKYGIKDLRFSEDGKEI
Sbjct: 61 DANPRFSPDGRLIAFTSKRSKEGRESELYLMPVDGGEARLLAKFKYGIKDLRFSEDGKEI 120
Query: 121 AVITPVEVKKVANEKEDVHVIDEIPFWFNGIGWIYGRRNALYLVDVESGKKRKVSPRNLD 180
AVITPVEVKKVANEKEDVHVIDEIPFWFNGIGWIYGRRNALYLVDVESGKKRKVSPRNLD
Sbjct: 121 AVITPVEVKKVANEKEDVHVIDEIPFWFNGIGWIYGRRNALYLVDVESGKKRKVSPRNLD 180
Query: 181 VLSVRFHNGKLYLLAQEDREKKPMISDVYVLEGKRVKKLTPGKWRILDFVPLSDGLILKA 240
VLSVRFHNGKLYLLAQEDREKKPMISDVYVLEGKRVKKLTPGKWRILDFVPLSDGLILKA
Sbjct: 181 VLSVRFHNGKLYLLAQEDREKKPMISDVYVLEGKRVKKLTPGKWRILDFVPLSDGLILKA 240
Query: 241 NTLERGFATTTSIYLYRNGELRRLFKEDLSAYNSLNSDVRGAQRAELIFKDGWIYFVATD 300
NTLERGFATTTSIYLYRNGELRRLFKEDLSAYNSLNSDVRGAQRAELIFKDGWIYFVATD
Sbjct: 241 NTLERGFATTTSIYLYRNGELRRLFKEDLSAYNSLNSDVRGAQRAELIFKDGWIYFVATD 300
Query: 301 GPRANLFRVNLDGKVERVIRGDRSVESFSVGDYIAFTAQDATTPTELYALRDGKEKRITD 360
GPRANLFRVNLDGKVERVIRGDRSVESFSVGDYIAFTAQDATTPTELYALRDGKEKRITD
Sbjct: 301 GPRANLFRVNLDGKVERVIRGDRSVESFSVGDYIAFTAQDATTPTELYALRDGKEKRITD 360
Query: 361 FNAWIRDYKLSKPEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAYGYAF 420
FNAWIRDYKLSKPEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAYGYAF
Sbjct: 361 FNAWIRDYKLSKPEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAYGYAF 420
Query: 421 MHEFQVLVAKGFVVIFSNPRGSDGYGEEFADIRGHYGERDYQDLMEVVDEALKRFDFIDE 480
MHEFQVLVAKGFVVIFSNPRGSDGYGEEFADIRGHYGERDYQDLMEVVDEALKRFDFIDE
Sbjct: 421 MHEFQVLVAKGFVVIFSNPRGSDGYGEEFADIRGHYGERDYQDLMEVVDEALKRFDFIDE 480
Query: 481 ERLGVTGGSYGGFMTNWIVGHTNRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPW 540
ERLGVTGGSYGGFMTNWIVGHTNRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPW
Sbjct: 481 ERLGVTGGSYGGFMTNWIVGHTNRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPW 540
Query: 541 SNLEGYWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGE 600
SNLEGYWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGE
Sbjct: 541 SNLEGYWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGE 600
Query: 601 NHDLSRSGRPKHRVKRLELIVGWFERWLKGR 631
NHDLSRSGRPKHRVKRLELIVGWFERWLKGR
Sbjct: 601 NHDLSRSGRPKHRVKRLELIVGWFERWLKGR 631
>pir||C71137 hypothetical protein PH0863 - Pyrococcus horikoshii
>gi|3257274|dbj|BAA29957.1| (AP000003) 642aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 642
Score = 1078 bits (2758), Expect = 0.0
Identities = 504/634 (79%), Positives = 574/634 (90%), Gaps = 6/634 (0%)
Query: 1 MMKKISEKDIEKFKLVGNLDASGKKVVFQVTEISIKENDYFSSIYLYDGRKVRRFTFGRK 60
M K +SEKD+ KFKLVGN+D K VFQVTEIS+K++DYFS +YLYDG++V+ FT G K
Sbjct: 11 MGKGLSEKDLGKFKLVGNVDVFKGKAVFQVTEISLKDDDYFSKLYLYDGKRVKPFTSGNK 70
Query: 61 DANPRFSPDGRLIAFTSKRSKEGRESELYLMPVDGGEARLLAKFKYGIKDLRFSEDGKEI 120
D+NPRFSP+G+LIAFTSKR KEG+ESELY++P DGGEARLLAKFKYGIK+LRF+EDGK I
Sbjct: 71 DSNPRFSPNGKLIAFTSKRDKEGKESELYVIPTDGGEARLLAKFKYGIKNLRFTEDGKSI 130
Query: 121 AVITPVEVKKVANEKEDVHVIDEIPFWFNGIGWIYGRRNALYLVDVESGKKRKVSPRNLD 180
AV+TP++V+K N+ DVH+I EIPFWFNG+GWIYG+RN +YLVDVESGKK++++P+NL+
Sbjct: 131 AVVTPIDVEKKGND--DVHIIREIPFWFNGVGWIYGKRNVVYLVDVESGKKKRLTPKNLN 188
Query: 181 VLSVRFHNGKLYLLAQEDREKKPMISDVYVLEGKRVKKLTPGKWRILDFVPLSDG-LILK 239
V +RFHNG+LY AQEDRE+KP+ISD+YVLE ++V+KLTPGKWRILDF+PL DG +LK
Sbjct: 189 VDQIRFHNGRLYFTAQEDRERKPLISDLYVLENRKVRKLTPGKWRILDFLPLDDGSFVLK 248
Query: 240 ANTLERGFATTTSIYLY--RNGELRRLFKE-DLSAYNSLNSDVRGAQRAELIFKDGWIYF 296
ANTLERG T IY Y + GEL++L K+ D +AYNSLNSDVRG+QRAEL++K+GWIY+
Sbjct: 249 ANTLERGIPTNAHIYHYDPKTGELKKLTKDLDRNAYNSLNSDVRGSQRAELVYKEGWIYY 308
Query: 297 VATDGPRANLFRVNLDGKVERVIRGDRSVESFSVGDYIAFTAQDATTPTELYALRDGKEK 356
VATDGPRANLFRVNLDGK+ERVI GDRSVESF +GDYIAFTAQDA TPTELY RDGKEK
Sbjct: 309 VATDGPRANLFRVNLDGKIERVIGGDRSVESFDIGDYIAFTAQDAVTPTELYIYRDGKEK 368
Query: 357 RITDFNAWIRDYKLSKPEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAY 416
++TDFN WI+ Y LSKPEHF+V ASDG EIDAW+MKPV+F+ G+KYPA+LEIHGGPKTAY
Sbjct: 369 KVTDFNKWIKGYTLSKPEHFKVKASDGVEIDAWVMKPVNFRKGKKYPAILEIHGGPKTAY 428
Query: 417 GYAFMHEFQVLVAKGFVVIFSNPRGSDGYGEEFADIRGHYGERDYQDLMEVVDEALKRFD 476
GYAFMHEF VL +KGFVVIFSNPRGSDGYGEEFADIRGHYGERDYQDLMEVVDEAL+RFD
Sbjct: 429 GYAFMHEFHVLTSKGFVVIFSNPRGSDGYGEEFADIRGHYGERDYQDLMEVVDEALRRFD 488
Query: 477 FIDEERLGVTGGSYGGFMTNWIVGHTNRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIG 536
FID ERLGVTGGSYGGFMTNWIVGHTNRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIG
Sbjct: 489 FIDGERLGVTGGSYGGFMTNWIVGHTNRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIG 548
Query: 537 GDPWSNLEGYWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAI 596
DPWSNLEGYWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQ +I+LKYLGK VELAI
Sbjct: 549 KDPWSNLEGYWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQLFISLKYLGKRVELAI 608
Query: 597 FPGENHDLSRSGRPKHRVKRLELIVGWFERWLKG 630
FPGENHDLSRSG+PKHRVKRLELI GW E+WLKG
Sbjct: 609 FPGENHDLSRSGKPKHRVKRLELIAGWMEKWLKG 642
>pir||F72568 probable acylamino-acid-releasing enzyme APE1832 - Aeropyrum pernix
(strain K1) >gi|5105522|dbj|BAA80835.1| (AP000062) 659aa
long hypothetical acylamino-acid-releasing enzyme
[Aeropyrum pernix]
Length = 659
Score = 433 bits (1101), Expect = e-120
Identities = 267/650 (41%), Positives = 372/650 (57%), Gaps = 26/650 (4%)
Query: 3 KKISEKDIEKFKLVGNLDAS--GKKVVFQVTEISIKENDYFSSIYLYDGRKVRRFTFGRK 60
K ++ +DI + V N S G KV + T+ KEN Y S I+L + R T G
Sbjct: 6 KPVTPEDIIRLTFVSNPSVSPEGDKVAYLATKADEKENTYRSGIWLAEEDSYRPLTGGPY 65
Query: 61 DANPRFSPDGRLIAFT-SKRSKEGRESELYLMPVDGGEARLLAKFKYGIKDLRFSEDGKE 119
D P +SPDG +IAF+ + S + + + ++ GGE ++L + +++S G
Sbjct: 66 DRCPAWSPDGEIIAFSRTVNSNQRKRHYIAIVSPKGGEPQVLHESVSPATSIKWSSQGSM 125
Query: 120 IAVIT--PVEVKKVANEKEDVHVIDEIPFWFNGIGWIYGRRNALYLVDVESGK----KRK 173
I ++ P + + DV ID IP WF+ GW++ R L ++ G+ K
Sbjct: 126 IGYLSRKPTGREWKPYSERDVLEIDRIPVWFDSEGWVFDRYWGLTVISYPGGEVLLEKGG 185
Query: 174 VSPRNLDVLSVRFHNGKLYLLAQEDREKKPMISDVYV--LEGKRVKKLTPGKW-RILDFV 230
V+ +D N +Y ++ + KKP I + + L R K L G + F
Sbjct: 186 VNYNIVDFDFAPDDNTIVYAVSTD--MKKPFIHKLVLWDLASGREKTLIEGLTIAAVAFD 243
Query: 231 PLSDGLILKANTLERGFATTTSIYLY--RNGELRRLFKE-DLSAYNSLNSDVRGAQRAEL 287
P + +KAN +RG + I++Y + E L + DL+ N++NSD RG
Sbjct: 244 PRGRYIAVKANDRKRGLFSHYKIFVYDLNSEEFVCLTCDLDLNTLNTVNSDARGPSCLRG 303
Query: 288 IFKD--GWIYFVATDGPRANLFRVNLDGKVERVIR-GDRSVESFSV---GDYIAFTAQDA 341
++ D G +Y+ + R + + G+ E V+ +V+ FS+ GD IA+
Sbjct: 304 MYWDDNGHLYYGVHNAGRMVVMKSRPLGEAEAVLDPSSATVDDFSISRGGDTIAYVKMGP 363
Query: 342 TTPTELYALRDGKEKRITDFNAWIRDYK-LSKPEHFRVTASDGKEIDAWIMKPVDF-KPG 399
T+P ++Y RD E R+TD NAW + + L++P +V + G IDAWI+ P D +
Sbjct: 364 TSPPDIYIYRDDNEYRLTDHNAWFAESRSLAEPVRLQVQSPLGGSIDAWILLPPDAGECS 423
Query: 400 RKYPAVLEIHGGPKTAYGYAFMHEFQVLVAKGFVVIFSNPRGSDGYGEEFADIRGHYGER 459
P +L IHGGPKT+YGYAF+HEFQ+L ++GF VI+SNPRGSDGY EEFAD+RG YG
Sbjct: 424 GCLPWILYIHGGPKTSYGYAFIHEFQMLASQGFAVIYSNPRGSDGYSEEFADLRGRYGVD 483
Query: 460 DYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVGHTNRFKAAVTQRSISNWIS 519
DY +LM+VVDEAL F +D +R GVTGGSYGG+MTN IV T RFKAAVTQRS SNWIS
Sbjct: 484 DYSELMKVVDEALSDFPQLDPQRGGVTGGSYGGYMTNVIVTKTRRFKAAVTQRSCSNWIS 543
Query: 520 FFGTTDIGYYFAPDQIGG-DPWSNLEGYWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEA 578
F+G +DIG+YFAP+ I +PW +LE Y + SPL N+ETPLLIIHSTED+RC L A
Sbjct: 544 FYGESDIGWYFAPELISAQEPWRDLEKYVDFSPLFSVENIETPLLIIHSTEDFRCPLSGA 603
Query: 579 LQFYIALKYLGKTVELAIFPGENHDLSRSGRPKHRVKRLELIVGWFERWL 628
+Q + ALK G L +FPGENH+LSRSG PK RV RL I WF+ L
Sbjct: 604 IQLFTALKLKGVETRLLVFPGENHNLSRSGTPKRRVARLRAIASWFKEHL 653
>sp|P39839|YUXL_BACSU PROBABLE PEPTIDASE YUXL >gi|7475770|pir||E70025 probable
acylaminoacyl-peptidase (EC 3.4.19.1) yuxL - Bacillus
subtilis >gi|2635720|emb|CAB15213.1| (Z99120) similar to
acylaminoacyl-peptidase [Bacillus subtilis]
Length = 657
Score = 415 bits (1056), Expect = e-115
Identities = 246/637 (38%), Positives = 366/637 (56%), Gaps = 35/637 (5%)
Query: 23 GKKVVFQVTEISIKENDYFSSIYLYDGRKVRR--FTFGRK-DANPRFSPDGRLIAFTSKR 79
G + + ++++ +++ Y S+I++Y+ + +T G K +PR+SPDGR +AF S R
Sbjct: 25 GTRAAYVKSQVNQEKDSYTSNIWIYETKTGGSVPWTHGEKRSTDPRWSPDGRTLAFISDR 84
Query: 80 SKEGRESELYLMPVDGGEARLLAKFKYGIKDLRFSEDGKEIAVITPVEVKKVANEKEDVH 139
EG ++LY+M +GGEAR L YG+ +S DG+ I V + + +++E
Sbjct: 85 --EGDAAQLYIMSTEGGEARKLTDIPYGVSKPLWSPDGESILVTISLGEGESIDDREKTE 142
Query: 140 V-------IDEIPFWFNGIGWIYGRRNALYLVDVESGKKRKVSPRNLDVLSVRFHNGKLY 192
+ + + +G G G L LV V+SG+ ++++ D F +
Sbjct: 143 QDSYEPVEVQGLSYKRDGKGLTRGAYAQLVLVSVKSGEMKELTSHKADHGDPAFSPDGKW 202
Query: 193 L-----LAQEDREKKPMISDVYV--LEGKRVKKLTP--GKWRILDFVPLSDGLILKANTL 243
L L + D KP DVY+ LE +K++TP G + F P L L N
Sbjct: 203 LVFSANLTETDDASKP--HDVYIMSLESGDLKQVTPHRGSFGSSSFSPDGRYLALLGNEK 260
Query: 244 ERGFATTTSIYLY--RNGELRRLFKE-DLSAYNSLNSD--VRGAQRAELIFKDGW-IYFV 297
E AT + +LY G L L + D+ ++L D + GA++ + KD Y +
Sbjct: 261 EYKNATLSKAWLYDIEQGRLTCLTEMLDVHLADALIGDSLIGGAEQRPIWTKDSQGFYVI 320
Query: 298 ATDGPRANLFRVNLDGKVERVIRGDRSVESFSVG---DYIAFTAQDATTPTELYALRDGK 354
TD ++ ++++G V + + SFS+ + + P+ELY++ G+
Sbjct: 321 GTDQGSTGIYYISIEGLVYPIRLEKEYINSFSLSPDEQHFIASVTKPDRPSELYSIPLGQ 380
Query: 355 E-KRITDFN-AWIRDYKLSKPEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEIHGGP 412
E K++T N ++R++ +S PE + DG ++ W+M+P + YP +L IHGGP
Sbjct: 381 EEKQLTGANDKFVREHTISIPEEIQYATEDGVMVNGWLMRPAQMEGETTYPLILNIHGGP 440
Query: 413 KTAYGYAFMHEFQVLVAKGFVVIFSNPRGSDGYGEEFAD-IRGHYGERDYQDLMEVVDEA 471
YG+ + HEFQVL AKG+ V++ NPRGS GYG+EF + +RG YG +DY D+M+ VDEA
Sbjct: 441 HMMYGHTYFHEFQVLAAKGYAVVYINPRGSHGYGQEFVNAVRGDYGGKDYDDVMQAVDEA 500
Query: 472 LKRFDFIDEERLGVTGGSYGGFMTNWIVGHTNRFKAAVTQRSISNWISFFGTTDIGYYFA 531
+KR ID +RLGVTGGSYGGFMTNWIVG TNRFKAAVTQRSISNWISF G +DIGY+F
Sbjct: 501 IKRDPHIDPKRLGVTGGSYGGFMTNWIVGQTNRFKAAVTQRSISNWISFHGVSDIGYFFT 560
Query: 532 PDQIGGDPWSNLEGYWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKT 591
Q+ D + + E W++SPLKYA NVETPLLI+H D RC + +A Q +IALK +GK
Sbjct: 561 DWQLEHDMFEDTEKLWDRSPLKYAANVETPLLILHGERDDRCPIEQAEQLFIALKKMGKE 620
Query: 592 VELAIFPGENHDLSRSGRPKHRVKRLELIVGWFERWL 628
+L FP +H+LSR+G P+ R+KRL I WF++ L
Sbjct: 621 TKLVRFPNASHNLSRTGHPRQRIKRLNYISSWFDQHL 657
>pir||F72455 probable acylamino-acid-releasing enzyme APE2290 - Aeropyrum pernix
(strain K1) >gi|5105991|dbj|BAA81302.1| (AP000064) 572aa
long hypothetical acylamino-acid-releasing enzyme
[Aeropyrum pernix]
Length = 572
Score = 339 bits (860), Expect = 6e-92
Identities = 211/580 (36%), Positives = 322/580 (55%), Gaps = 44/580 (7%)
Query: 64 PRFSPDGRLIAFTSKRS--KEGRESELYLMPVDGGEARLLAKFKYGIKDLRFSEDGKEIA 121
P +SPD +AF S+R K + S LY++ GGE R +A F +G+ +L ++ K +
Sbjct: 2 PSWSPDASKLAFASRRGSGKGEKGSGLYIVG-RGGEPRRVAWFTHGVSELGWASATK-VY 59
Query: 122 VITPVEVKKVANEKEDVHVIDEIPFWFNGIGWIYGRRNALYLVDVESGKKRKVSPRNLDV 181
V+ PV +K ++ D D +P WF+ G + G + ++LVD ESG+ +++ +L V
Sbjct: 60 VVAPVADEKTRDKDGDYVATDRLPLWFDSSGLVAGLADQIHLVDAESGRTSRLTSEDLGV 119
Query: 182 LSVRFHNGKLYLLAQEDREKKPMISDV-----------YVLEGKRVKKLTPGKWRILDFV 230
L+ +Y + R P+ + V VLEG V +L
Sbjct: 120 LTAEPCGNSIYYVTLR-RWADPLDTVVKSVPISGGEPETVLEGLTVSQLR---------- 168
Query: 231 PLSDGLILKANTLERGFATTTSIYLYRNGELRRLFKEDLSAYNSLNSDVRGAQRAELIFK 290
++ L + A+ E G A+ + +YL + + N + + G E +
Sbjct: 169 CINGKLFMLAHKREIGLASHSKLYLLEDRGKASCLTCGILDRNIWS--IAGGLGGEPV-- 224
Query: 291 DGWIYFVATDGPRANLFRVNLDGKVERVIRGDR-SVESFSVGDYIAFTAQDATTPTELYA 349
V D R+ + V +G+VE ++RGD V++ S G+ + + A T P E+Y
Sbjct: 225 -----IVYADRGRSVIAAV--EGRVEDLVRGDMIVVQADSNGEEVVYIASSPTEPPEVYR 277
Query: 350 LRDGKEKRITDFNAW-IRDYKLSKPEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEI 408
+ G +R++ N W + +++L KP V A +G+ ++ W ++P GRK P +L I
Sbjct: 278 FKGGDVERVSSINRWVVEEFRLYKPRRVEVEA-EGEVVEGWYIEPEG--EGRK-PLILFI 333
Query: 409 HGGPKTAYGYAFMHEFQVLVAKGFVVIFSNPRGSDGYGEEFADIRGHYGERDYQDLMEVV 468
HGGPK YGY F E Q+ ++GF V ++NPRGSDGY EEFADIRG YG+ DY+ LM+ +
Sbjct: 334 HGGPKGMYGYGFYGEMQLFASEGFTVAYANPRGSDGYEEEFADIRGRYGDTDYKQLMKFL 393
Query: 469 DEALKRFDFIDEERLGVTGGSYGGFMTNWIVGHTNRFKAAVTQRSISNWISFFGTTDIGY 528
D ++ D +DE ++ VTG SYGG+MTN IV T+RF+AAV++ I++WI+ F DIGY
Sbjct: 394 DAVVEGSD-VDEGKMAVTGISYGGYMTNVIVTKTSRFRAAVSENGIADWIADFWAADIGY 452
Query: 529 YFAPDQIGGDPWSNLEGYWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYL 588
+F PDQIGG P NLE Y ++SP +A NV TP+++IHS EDYRC++ +AL + ALK
Sbjct: 453 WFDPDQIGGTPLDNLEEYVKRSPAFHAKNVNTPVMLIHSMEDYRCFIDQALAMHTALKVN 512
Query: 589 GKTVELAIFPGENHDLSRSGRPKHRVKRLELIVGWFERWL 628
GK L +F +H S P+HR KRLEL + W + L
Sbjct: 513 GKESFLVVFTKGSHGHSILASPRHRRKRLELKLKWIKEKL 552
>pir||E75057 peptidase PAB1418 - Pyrococcus abyssi (strain Orsay)
>gi|5458867|emb|CAB50354.1| (AJ248287) peptidase
[Pyrococcus abyssi]
Length = 632
Score = 317 bits (804), Expect = 2e-85
Identities = 211/638 (33%), Positives = 353/638 (55%), Gaps = 53/638 (8%)
Query: 6 SEKDIEKFKLVGNLDASGKKVVFQVTEISIKENDYFSSIYLY---DGRKVRRFTFGRKDA 62
+EK KF + + G + + +T+ ++ N Y S+I L DG K RF +DA
Sbjct: 17 NEKTFTKFAYLSDPRIRGSTIAYVLTKANLDNNKYESTIVLENLEDGSK--RFI---EDA 71
Query: 63 N-PRFSPDGRLIAFTSKRSKEGRESELYLMPVDGGEARLLAKFKYGIKDLRFSEDGKEIA 121
+ PR SPDG+ IAF + ++E + +++++ + A+ + + K I+ L +++D + +
Sbjct: 72 SMPRISPDGKKIAFM-RFNEEKKVAQIWVADMKTLSAKKVLEAK-NIRSLEWNDDSRRLL 129
Query: 122 VITPVEVKKVANEKEDVHVIDEIPFWFNGIGWIYGRRNALYLVDVESGK--KRKVSPRNL 179
VI K+ + ED D++P WF+ +G+ G + ++VD E+ + ++ PR
Sbjct: 130 VIG---FKR--RDDEDFIFEDDVPAWFDNMGFFDGEKTTFWIVDTEAEEVIEQFEKPR-- 182
Query: 180 DVLSVRFHNGKLYLLAQEDREKKPMISDVYVL----EGKRVKKLTPGKWRILDFVPLSDG 235
S +G ++ R+ P + + +G+ K + +D SDG
Sbjct: 183 --FSSGVWHGDSIVVNVPYRDTIPRYFKYWNIYLWKDGEEEKLFEKVSFHAID----SDG 236
Query: 236 --LILKANTLERGFATTTSIYLYRNGELRRLFKEDLSAYNSLNSDVRGAQRAELIFKDGW 293
++L ++ + +Y+Y +GE++ + ++S R A +A++ KDG
Sbjct: 237 KNILLYGKPEKKYMSEHDKLYIY-DGEVKGI----------MDSIDREAGQAKI--KDGK 283
Query: 294 IYFVATDGPRANLFRVNLDGKVERVIRGDRSVESFSVGDYIAFTAQDATTPTELYALRDG 353
+YF + NL+ DG ++ + +G + F V + + + + AT ELY + DG
Sbjct: 284 VYFTLYEEGSVNLYL--WDGDIKEIAKGKHWIMGFDVDEKVVYLKETATRLRELY-IWDG 340
Query: 354 KEKRITDFNAWI-RDYKLSKPEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEIHGGP 412
+E+++TD+N I K +P+HF+ + D EID W +KP + K G K P ++ +HGGP
Sbjct: 341 EERQLTDYNGLIFSKLKTFEPKHFKFKSID-LEIDGWYIKP-ELKEGEKAPVIVFVHGGP 398
Query: 413 KTAYGYAFMHEFQVLVAKGFVVIFSNPRGSDGYGEEFA-DIRGHYGERDYQDLMEVVDEA 471
K YGY F +E Q++ +KG+ +++ NPRGS+GY E+FA + G D+QD++ ++E
Sbjct: 399 KGMYGYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEF 458
Query: 472 LKRFDFIDEERLGVTGGSYGGFMTNWIVGHTNRFKAAVTQRSISNWISFFGTTDIGYYFA 531
K D ER+G+TG SYGGFMTNW + ++ FKA +++ IS W++ + +DIG +F
Sbjct: 459 FKLEPQADRERVGITGISYGGFMTNWALTQSDLFKAGISENGISYWLTSYAFSDIGLWFD 518
Query: 532 PDQIGGDPWSNLEGYWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKT 591
+ IG +P N E + + SPL YA NV+ PLL+IHS EDYRC L ++L FY LK LGK
Sbjct: 519 KEVIGENPLEN-ENFRKLSPLFYAKNVKAPLLLIHSLEDYRCPLDQSLMFYHVLKDLGKE 577
Query: 592 VELAIFPGENHDLSRSGRPKHRVKRLELIVGWFERWLK 629
V +AIF H S G P+HR+KR +L + +FER LK
Sbjct: 578 VYIAIFKRGAHGHSIRGSPRHRMKRYKLFMEFFERKLK 615
>pir||E75551 probable acyl-peptide hydrolase - Deinococcus radiodurans (strain
R1) >gi|6457834|gb|AAF09754.1|AE001879_2 (AE001879)
acyl-peptide hydrolase, putative [Deinococcus
radiodurans]
Length = 655
Score = 317 bits (803), Expect = 3e-85
Identities = 222/638 (34%), Positives = 328/638 (50%), Gaps = 43/638 (6%)
Query: 23 GKKVVFQVTEISIKEND----------YFSSIYLYDGRKVRRFTF---GRKDANPRFSPD 69
GK+V F + +IS ++ Y S ++L +G R T GR D+ PR+SPD
Sbjct: 29 GKQVAFVLAQISEEDPAKPDKDFARPRYRSGLWLSEGGAARPLTHAETGRGDSAPRWSPD 88
Query: 70 GRLIAFTSKRSKEGRESELYLMPVDGGEARLLAKFKYGIKDLRFSEDGKEIAVITPVEVK 129
G+ +AF RS ++ L L+P+ GGEAR + FK G+ ++S DG+ IA T + +
Sbjct: 89 GQNLAFV--RSAGEVKAALMLLPLKGGEARRVTHFKNGVSGPQWSPDGRFIAFTTTADTE 146
Query: 130 KVANEKEDVHVIDEIPFWFNGIGWIYGRRNALYLVDVESGKKRKVSPRNLDVLSVRF--- 186
+E+ + V+ + NG W+ R AL+L DVE+ K R+ + + ++ +
Sbjct: 147 DKRDERGEARVLTRPVYRANGADWLPERPAALWLYDVEADKLREWYAPEIGIGALSWWPD 206
Query: 187 HNGKLYLLAQEDREKKPMISDVYVLEGKRV------KKLTPGKWRILDFVPLSDG--LIL 238
G L + ++++ + DVY L +KL P DG L
Sbjct: 207 SRGVLIVQSEDEWQASQWRQDVYDLPLPTADAPAAPQKLLDWNSAAHGLAPHPDGQRFAL 266
Query: 239 KANTLERGFATTTSIYLYRNGELRRLFK-EDLSAYNSLNSDVR-GAQRAELIFKDG-WIY 295
+G +YL NG+ RRL D +++ D GA + DG +
Sbjct: 267 IGRPAGKGNTEHAHLYLIENGQHRRLDTGHDHPVGDAVGGDCHVGAFPEGPRWLDGDTLL 326
Query: 296 FVATDGPRANLFRVNLDGKVERVIRGDRSVES-FSVGDY-IAFTAQDATTPTELYALRDG 353
F +T LF ++ G V+ + V S F+ ++ +A + AT E+ +
Sbjct: 327 FSSTVRGSVGLFTAHIGGGVKAYDHDPQGVISAFTANEHGVALIRESATRFPEV----EL 382
Query: 354 KEKRITDFNAWIRDYKLSKPEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEIHGGPK 413
+R+TD +A + + +P+ G E + W++ P + +K PA+L IHGGP
Sbjct: 383 NGQRVTDLHARF-PFPVREPQRVTFETELG-EGEGWVLLP---EGEQKVPALLNIHGGPH 437
Query: 414 TAYGYAFMHEFQVLVAKGFVVIFSNPRGSDGYGEEFAD-IRGHYGERDYQDLMEVVDEAL 472
T YG+ F HEFQ++ A+G+ V +SNPRGS GYG+ + D I G +G D DL+ D L
Sbjct: 438 TDYGHGFTHEFQLMAARGYGVCYSNPRGSVGYGQAWVDAIYGRWGTVDADDLLNFFDRCL 497
Query: 473 KRFDFIDEERLGVTGGSYGGFMTNWIVGHTNRFKAAVTQRSISNWISFFGTTDIGYYFAP 532
+ +D + V GGSYGGFMTNWI GHT RF+AA+T R ISN ISF GT+DIG F
Sbjct: 498 EAVPRLDAAKTAVMGGSYGGFMTNWITGHTTRFQAAITDRCISNLISFGGTSDIGLRFWD 557
Query: 533 DQIGGDPWSNLEG--YWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGK 590
D++G D + W+ SPL+Y NV+TP LI+HS D+RC + +A Q+Y AL
Sbjct: 558 DELGLDFSRRADALKLWDLSPLQYVENVKTPTLIVHSVLDHRCPVEQAEQWYAALHKHQV 617
Query: 591 TVELAIFPGENHDLSRSGRPKHRVKRLELIVGWFERWL 628
V FP ENH+LSRSGRP R+ RL W ERWL
Sbjct: 618 PVRFVRFPEENHELSRSGRPDRRLTRLNEYFAWLERWL 655
>pir||F71174 hypothetical protein PH0594 - Pyrococcus horikoshii
>gi|3257000|dbj|BAA29683.1| (AP000002) 622aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 622
Score = 316 bits (802), Expect = 4e-85
Identities = 207/636 (32%), Positives = 352/636 (54%), Gaps = 51/636 (8%)
Query: 7 EKDIEKFKLVGNLDASGKKVVFQVTEISIKENDYFSSIY---LYDGRKVRRFTFGRKDAN 63
EK KF + + V + +T+ +++ N Y ++I L DG R+F +DA+
Sbjct: 8 EKTFTKFAYLSDPRTRKNLVAYVLTKANLESNKYENTIVIENLEDGS--RKFI---EDAS 62
Query: 64 -PRFSPDGRLIAFTSKRSKEGRESELYLMPVDGGEARLLAKFKYGIKDLRFSEDGKEIAV 122
PR SPDG+ IAF + ++E + +++++ + A+ + + K I+ + +++D + +
Sbjct: 63 MPRISPDGKKIAFM-RFNEEKKTAQIWVADLKTLSAKKVLEAK-NIRSIEWNQDSRRLLA 120
Query: 123 ITPVEVKKVANEKEDVHVIDEIPFWFNGIGWIYGRRNALYLVDVESGK--KRKVSPRNLD 180
V K+ E ED D++P WF+ +G+ G + +++D E + ++ PR
Sbjct: 121 ---VGFKR--REDEDFIFEDDVPAWFDNMGFFDGEKTTFWVIDTEGEEVIEQFEKPR--- 172
Query: 181 VLSVRFHNGKLYLLAQEDREKKPMIS---DVYVLEGKRVKKLTPGKWRILDFVPLSDG-- 235
S +G +++ R+ P D+Y+ + +KL ++ + SDG
Sbjct: 173 -FSSGIWHGDSIVVSVPHRDVIPRYFKYWDIYLWKDGEEEKLFE---KVSFYAIDSDGER 228
Query: 236 LILKANTLERGFATTTSIYLYRNGELRRLFKEDLSAYNSLNSDVRGAQRAELIFKDGWIY 295
++L ++ + IY+Y +GE++ + + ++ +V A+ ++G +Y
Sbjct: 229 ILLYGKPEKKYVSEHDKIYIY-DGEVKGILDD-------IDREVAQAK-----IRNGKVY 275
Query: 296 FVATDGPRANLFRVNLDGKVERVIRGDRSVESFSVGDYIAFTAQDATTPTELYALRDGKE 355
F + NL+ DG+V + +G + F + + + + AT P ELY L DG+E
Sbjct: 276 FTLFEEGSVNLYL--WDGEVREIAKGKHWIMGFDADERLIYLKETATRPAELY-LWDGEE 332
Query: 356 KRITDFNAWI-RDYKLSKPEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKT 414
+++TD+N I + K +P HFR + D E+D W +KP + K G K P ++ +HGGPK
Sbjct: 333 RQLTDYNGLIFKKLKTFEPRHFRFKSID-LELDGWYIKP-EIKEGEKAPVIVFVHGGPKG 390
Query: 415 AYGYAFMHEFQVLVAKGFVVIFSNPRGSDGYGEEFA-DIRGHYGERDYQDLMEVVDEALK 473
YGY F +E Q++ +KG+ +++ NPRGS+GY E+FA + G D+QD++ ++E L+
Sbjct: 391 MYGYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEFLR 450
Query: 474 RFDFIDEERLGVTGGSYGGFMTNWIVGHTNRFKAAVTQRSISNWISFFGTTDIGYYFAPD 533
D ER+G+TG SYGG+MTNW + ++ FKA +++ IS W++ + +DIG +F +
Sbjct: 451 LEPQADRERIGITGISYGGYMTNWALTQSDLFKAGISENGISYWLTSYAFSDIGLWFDKE 510
Query: 534 QIGGDPWSNLEGYWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVE 593
IG +P N E Y + SPL YA NV+ PLL+IHS EDYRC L ++L FY LK LGK V
Sbjct: 511 VIGDNPLEN-ENYRKLSPLFYAKNVKAPLLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVY 569
Query: 594 LAIFPGENHDLSRSGRPKHRVKRLELIVGWFERWLK 629
+AIF H S G P+HR+KR +L + +FER LK
Sbjct: 570 IAIFKKGAHGHSIRGSPRHRMKRYKLFMEFFERKLK 605
>gb|AAK42808.1| Acylaminoacyl-peptidase, putative (apeH-3) [Sulfolobus
solfataricus]
Length = 591
Score = 262 bits (662), Expect = 1e-68
Identities = 200/623 (32%), Positives = 322/623 (51%), Gaps = 51/623 (8%)
Query: 14 KLVGNLDASGKKVVFQVTEISIKENDYFSSIYLYDGRKVRRFTFGRKDANPRFSPDGRLI 73
KLV + K+ F V E I+E+ Y SSIYL ++R TF +++P+F+ D
Sbjct: 11 KLVPEITIENGKL-FHV-ETWIEEDKYKSSIYL----NLKRITFQGNESSPKFNNDKLYF 64
Query: 74 AFTSKRSKEGRESELYLMPVDGGEARLLAKFKYGIKDLRFSEDGKEIAVITPVEVKKVAN 133
+ E++LY GE +++ F I F G I VI K
Sbjct: 65 IRNEEAKSSLLEAQLY------GEPKVIFTFSGKISKYEFHNKG--ILVIAEENTDKTLP 116
Query: 134 EKEDVHVIDEIPFWFNGIGWIYGRRNALYLVDVESGKK-RKVSPRNLDVLSVRFHNGKLY 192
+ + +I + F+ G + R++ LYL D GK R++ N DV + + ++
Sbjct: 117 FRAE-----KIKYRFDSRGLLRARQS-LYLFD---GKDLRRLVTGNFDVTDLATNGNRVV 167
Query: 193 LLAQEDREKKPMISDVYV-LEGKRVKKLTPGKWRILDFVPLSDGLILKANTLERGFATTT 251
+ A +D + + + V +E + ++T + S+G I +G
Sbjct: 168 ISATKDGDDYGLGNLYEVNIETGELNRITKEDGTVQAIAMNSEGKIAFLGH-RKGLTPWA 226
Query: 252 SIYLYRNGELRRLFKEDLSAYNSLNSDVRGAQRAELIFKDGWIYFVATDGPRANLFRVNL 311
S+ + E + + + N + +D+ + ++F+ I + +G +++++++
Sbjct: 227 SLEIMLPEE-GKSYMCGKTCGNKVLTDLFDGVKDRIVFEKDLILSLGQEGGTSHIYQIS- 284
Query: 312 DGKVERVIRGDRSVESFSVGDYIAFTAQDATTPTELYALRDGKEKRIT-DFNAWIRDYKL 370
D KV++V G+ V F + + A +TP + L K + I D N I+ Y
Sbjct: 285 DNKVDKVTSGNIMVRGFDYSN--SELAYFYSTPEKPVIL---KYRDIEYDPNPNIKGYT- 338
Query: 371 SKPEHFRVTASDGKEIDAW-IMKPVDFKPGRKYPAVLEIHGGPKTAYGYAFMHEFQVLVA 429
PE V S+G E++ W I+K + P +L IHGGP AYGY + EFQ V
Sbjct: 339 --PERITVN-SNGVEVEGWSIIKDPNA------PTILFIHGGPHMAYGYGYFIEFQFFVD 389
Query: 430 KGFVVIFSNPRGSDGYGEEFADIR-GHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGG 488
GF VI++NPRGS GYGEEFA G +G +D++DLM V+ +R+ + + G+TGG
Sbjct: 390 NGFNVIYANPRGSQGYGEEFAKACVGDWGGKDFEDLMNFVNTVKERYSL--KGKFGITGG 447
Query: 489 SYGGFMTNWIVGHTNRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIG-GDPWSN--LEG 545
SYGGFMTNWIV T+ F AA+++RSISN +S GT+DIG++F + G DPWS +E
Sbjct: 448 SYGGFMTNWIVTKTSMFSAAISERSISNLVSMCGTSDIGFWFNAIESGIADPWSTEGIEK 507
Query: 546 YWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDLS 605
+ SP+ Y NV+TP ++IH EDYRC + +A QFY+ALK G L + G++H+ +
Sbjct: 508 LMKMSPIYYVKNVKTPTMLIHGEEDYRCPIEQAEQFYVALKMQGVPTTLVRYQGDSHEHA 567
Query: 606 RSGRPKHRVKRLELIVGWFERWL 628
R G+PK+ + RL+ + WF ++L
Sbjct: 568 RRGKPKNMIDRLKTKLEWFSKYL 590
>gb|AAG20414.1| (AE005114) acylaminoacyl-peptidase; YuxL [Halobacterium sp. NRC-1]
Length = 674
Score = 245 bits (620), Expect = 8e-64
Identities = 192/605 (31%), Positives = 279/605 (45%), Gaps = 43/605 (7%)
Query: 53 RRFTFGR-KDANPRFSPDGRLIAFTSKRSKEGR-ESELYLMPVDGGEARLLAKFKYGIKD 110
RRFT DA P +SP G +AF S R G +L+++PVDGGEA + G+ +
Sbjct: 58 RRFTAADGTDAEPAWSPTGDRLAFVSTRGDAGGGRPQLWVVPVDGGEATRITDVIGGVSN 117
Query: 111 LRFSEDGKEIAVITPVEVKKVANEKEDVH------------VIDEIPFWFNGIGWIYGRR 158
+ + DG +A + V + A E + H VID + + G R
Sbjct: 118 IAWGPDGDRVAFLQAVRPAERAEELDREHDGEYERDTPDPRVIDR-QMYRGHTSYRDGAR 176
Query: 159 NALYLVDVESGKKRKVSPRNLDVLSVRF-HNGKLYLLAQEDREKKPMISDVYVLEGKRVK 217
+Y+ D+ +G+ +V+ + + +G LY + + + ++
Sbjct: 177 RHVYVADLAAGRVDRVTAGVAECGGPAWGDDGTLYYPIRRGLDADDRLEWA-------IE 229
Query: 218 KLTPGKWRILDFVPLSDGL--ILKANTLERGFATTTSIYLYRNGELRRLFKEDLSAYNSL 275
TP V +G+ L + + TT + +F D A + L
Sbjct: 230 AATPADSADSTVVTTVEGMGPTLAVHGSRVAYTTTPADDPTLTQTAVEVFDRDTGATDRL 289
Query: 276 NSDV------RGAQRAELIFKDGWIYFVAT-DGPRANLFRVNLDGKVERVI-RGDRSVES 327
V R A A DG +V T D L RV D +RV+ GDR V +
Sbjct: 290 TDGVDRTVAERTAGHAPEWGPDGEHLYVCTPDEGGYVLRRVAADTGDDRVVLAGDRHVHA 349
Query: 328 FSVG-DYIAFTAQDATTPTELYALRD--GKEKRITDFNA-WIRDYKLSKPEHFRVTASDG 383
FSV D +A + P E+ A G+E +T N ++ + +SKPE + G
Sbjct: 350 FSVSADAVAVVQSEWDHPGEVVAATPMGGEEVTLTRANRDYLDERAVSKPESVWIDGPAG 409
Query: 384 KEIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAYGYA--FMHEFQVLVAKGFVVIFSNPRG 441
+I W++ P +F P YP V+ +HGGP + A HEFQ L A+G+VV + NPRG
Sbjct: 410 -DIQGWVLTPPEFDPEETYPLVVNVHGGPHLMWSAAGTMWHEFQTLAARGYVVFWCNPRG 468
Query: 442 SDGYGEEFAD-IRGHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVG 500
S GYG+E+ + +G D+M V R D++D + +TGGS+GGFMT W VG
Sbjct: 469 STGYGQEWLRAVERDWGAVTLADVMAGVAAVTDR-DYVDADNAFITGGSFGGFMTGWAVG 527
Query: 501 HTNRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPWSNLEGYWEKSPLKYAPNVET 560
HT+ F AV QR + + F+GTTD Y + DP + W +SP + V+T
Sbjct: 528 HTDAFAGAVAQRGVYDLTGFYGTTD-AYALVEGEFDTDPVRDNAFLWAQSPAAHTDAVDT 586
Query: 561 PLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDLSRSGRPKHRVKRLELI 620
P L++HS DYR A FY LK G L +PGE HDLSRSG P H V R+E I
Sbjct: 587 PTLLVHSEADYRTPANTAELFYRLLKKHGVDTRLVRYPGEGHDLSRSGDPGHVVDRIERI 646
Query: 621 VGWFE 625
WF+
Sbjct: 647 AAWFD 651
>pir||B82580 alanyl dipeptidyl peptidase XF2260 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9107416|gb|AAF85059.1|AE004038_8
(AE004038) alanyl dipeptidyl peptidase [Xylella
fastidiosa]
Length = 709
Score = 151 bits (377), Expect = 3e-35
Identities = 96/346 (27%), Positives = 182/346 (51%), Gaps = 17/346 (4%)
Query: 294 IYFVATDGPRANLFRVNL-DGKVERVIRGDRSVES-FSVGDYIAFTAQDATTPTELY--- 348
+Y A D LF+V++ GKVE+ + G+ SV + G +AF + +++
Sbjct: 368 LYVNADDHGEHPLFKVDIASGKVEKWV-GEGSVHAPVLAGGKLAFARNSLKSADQIFVTD 426
Query: 349 ALRDGKEKRITDFNAWI-RDYKLSKPEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLE 407
A+ G + IT + + +L E F + + + +++KP D++PG+KYP
Sbjct: 427 AVARGPLQAITSATGEVLQQVRLGDFEQFSFKGWNDETVYGYVVKPYDYQPGKKYPVAFL 486
Query: 408 IHGGPKTAYGYAFMHEF--QVLVAKGFVVIFSNPRGSDGYGEEFAD-IRGHYGERDYQDL 464
IHGGP+ ++G ++ + + Q +G+ V+ + GS GYG+ F D I H+G+R +DL
Sbjct: 487 IHGGPQGSFGNSWGYRWNPQTYAGQGYAVVMIDFHGSTGYGQAFTDAISQHWGDRPLEDL 546
Query: 465 MEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVGHTNR-FKAAVTQRSI-SNWISFFG 522
+ A +++ F++ ++ G SYGG+M WI GH N+ +K V + N + +
Sbjct: 547 QKGWAAAQQQYPFLNGDKACALGASYGGYMVYWIAGHWNQPWKCLVDHDGVFDNRMMGYA 606
Query: 523 TTDIGYYFAPDQIGGDPWSNLEGYWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQFY 582
T ++ +F+ + GG PW N GY + +P+ + P+L+IH +D+R + + L +
Sbjct: 607 TEEL--WFSEWENGGTPWENPAGYEQFNPVLHVDKWRVPMLVIHGQKDFRIPVEQGLAAF 664
Query: 583 IALKYLGKTVELAIFPGENHDLSRSGRPKHRVKRLELIVGWFERWL 628
AL+ G +L F ENH + +P++ ++ + + W ++++
Sbjct: 665 GALQRKGIESKLLYFHDENHWVL---KPQNSIQWHDTVNAWLKKYI 707
>emb|CAB88242.1| (AL353012) putative dipeptidyl peptidase; possibly secreted
[Schizosaccharomyces pombe]
Length = 683
Score = 142 bits (354), Expect = 1e-32
Identities = 82/252 (32%), Positives = 128/252 (50%), Gaps = 9/252 (3%)
Query: 383 GKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAYGYAFMHEFQ--VLVAKGFVVIFSNPR 440
G I AWI+KP F +KYP + IHGGP+ ++ ++ + V GF+V +P
Sbjct: 426 GHRIHAWIVKPESFDKSKKYPVAVLIHGGPQGSWTDSWSTRWNPAVFANAGFIVFALDPT 485
Query: 441 GSDGYGEEFAD-IRGHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIV 499
GS GYG+ F D I +G + Y+D+ V+ + D E++ G SYGG+M NWI
Sbjct: 486 GSTGYGQRFTDSIALDWGGKPYKDIELGVEYIKNHLSYADSEKMVALGASYGGYMINWIQ 545
Query: 500 GHT--NRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPWSNLEGYWEKSPLKYAPN 557
GH +F+A V + N ++ F T+ YF+ GG PW N Y +P +
Sbjct: 546 GHPLGRQFRALVCHDGVFNTLNTFYNTE-ELYFSIHDFGGTPWENRVIYERWNPSNFVNY 604
Query: 558 VETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDLSRSGRPKHRVKRL 617
TP L+IHS++DYR E + + L+Y G L +F ENH + +P + ++
Sbjct: 605 WATPELVIHSSKDYRLTESEGIAAFNVLQYKGIPSRLLVFEDENHWVI---KPDNSLRWH 661
Query: 618 ELIVGWFERWLK 629
+ ++ W + K
Sbjct: 662 KEVLSWILHYTK 673
>gb|AAF20265.1| (AF059279) dipeptidyl-peptidase [Entamoeba dispar]
Length = 663
Score = 132 bits (329), Expect = 1e-29
Identities = 95/337 (28%), Positives = 155/337 (45%), Gaps = 17/337 (5%)
Query: 305 NLFRVNLDGKVERVIRGDRSV--ESFSVGDYIAFTA------QDATTPTELYALRDGKEK 356
N++ V LD + R D ++ + + G ++ T T P EL+ + K
Sbjct: 328 NVYIVGLDTSKSELTREDVNIITQKGTAGSFVFTTTGIIYEYNSFTLPQELFIFENKVIK 387
Query: 357 RITDFNAWIRD-YKLSKPEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKTA 415
+IT N + K + + T ++ +I A+I P + K KYP +L HGGP++
Sbjct: 388 QITHINQEVLSTIKFGEYKEVHYTGANNDQIHAFITYPPNMKTNTKYPVILYTHGGPESP 447
Query: 416 YGYAFMHEF--QVLVAKGFVVIFSNPRGSDGYGEEFAD-IRGHYGERDYQDLMEVVDEAL 472
+ F + + QV+ A+G++V N GS YG+EF IR ++G ++DLM+ +D
Sbjct: 448 WTNNFHYRWNPQVIAAQGYIVFAPNFHGSGSYGDEFLKAIRKNWGGWPFEDLMKGMDYLK 507
Query: 473 KRFDFIDEERLGVTGGSYGGFMTNWIVG-HTNRFKAAVTQRSISNWISFFGTTDIGYYFA 531
+D + G SYGG+M NWI +T RFK + I + + D YF
Sbjct: 508 TNEPIVDIDNACAMGASYGGYMMNWINSQNTGRFKCIICHDGIMDSEGSYYYMD-EMYFL 566
Query: 532 PDQIGGDPWSNLEGYWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKT 591
+ G + + Y + SPL Y TP L IH DYR + Q ++ L+
Sbjct: 567 ETEFGYPMYEDNTYYKKYSPLNYVNGYNTPQLTIHGGSDYRIDVVAGYQQFVTLQRKNIE 626
Query: 592 VELAIFPGENHDLSRSGRPKHRVKRLELIVGWFERWL 628
+L I+P ENH + RP + + + W ++L
Sbjct: 627 SKLVIYPEENHWVL---RPYNSIDWHTQVFNWLAKYL 660
>gb|AAF20264.1|AF059278_1 (AF059278) dipeptidyl-peptidase [Entamoeba histolytica]
Length = 665
Score = 129 bits (320), Expect = 1e-28
Identities = 94/337 (27%), Positives = 154/337 (44%), Gaps = 17/337 (5%)
Query: 305 NLFRVNLDGKVERVIRGDRSV--ESFSVGDYIAFTA------QDATTPTELYALRDGKEK 356
N++ V LD + R D ++ + + G ++ T T P EL+ + K
Sbjct: 330 NVYIVGLDTSKSELTREDVNIITQKGTAGSFVFTTTGIIYEYNSFTLPQELFLYENKVIK 389
Query: 357 RITDFNAWIRD-YKLSKPEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKTA 415
+IT N + K + + T ++ +I A+I P + K KYP +L HGGP++
Sbjct: 390 QITHINQEVLSTIKFGEYKEIHYTGANNDQIHAFITYPPNMKTNTKYPVILYTHGGPESP 449
Query: 416 YGYAFMHEF--QVLVAKGFVVIFSNPRGSDGYGEEFAD-IRGHYGERDYQDLMEVVDEAL 472
+ F + + QV+ A+G++V N GS YG+ F IR ++G ++DLM+ +D
Sbjct: 450 WTNNFHYRWNPQVIAAQGYIVFAPNFHGSGSYGDAFLKAIRKNWGGWPFEDLMKGMDYLK 509
Query: 473 KRFDFIDEERLGVTGGSYGGFMTNWIVG-HTNRFKAAVTQRSISNWISFFGTTDIGYYFA 531
+D + G SYGG+M NWI +T RFK + I + + D YF
Sbjct: 510 TSEPLVDIDNACAMGASYGGYMMNWINSQNTGRFKCIICHDGIMDSEGSYYYMD-EMYFL 568
Query: 532 PDQIGGDPWSNLEGYWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKT 591
+ G + + Y + SPL Y TP L IH DYR + Q ++ L+
Sbjct: 569 ETEFGYPMYEDDTYYKKYSPLNYVNGYNTPQLTIHGGSDYRIDVVAGYQQFVTLQRKNIE 628
Query: 592 VELAIFPGENHDLSRSGRPKHRVKRLELIVGWFERWL 628
+L I+P ENH + RP + + + W ++L
Sbjct: 629 SKLVIYPEENHWVL---RPYNSIDWHAQVFDWLAKYL 662
>emb|CAC11802.1| (AL445065) hypothetical protein [Thermoplasma acidophilum]
Length = 583
Score = 129 bits (320), Expect = 1e-28
Identities = 133/457 (29%), Positives = 220/457 (48%), Gaps = 49/457 (10%)
Query: 161 LYLVDVESGKKRKVSPRNLDVLSVRFHNGKLYLLAQE-DREKKPMISDVY-VLEGKRVKK 218
LYL+D SG K+ NL + +G +Y +A + +E S VY ++ GK +
Sbjct: 139 LYLMD-SSGIKKITD--NLQIWEFSSSDGVIYTVASKCPQESCWYASKVYRIVPGKDPEI 195
Query: 219 L-TPGKWRILDFVPLSDG---LILKANTLERGFATTTSIYLYRNGELRRLFKEDLSAYNS 274
+ PGK +I +DG L++ +RG + I LY +G R + + S+Y+
Sbjct: 196 IYDPGKRQIGKIT--TDGKRSAFLESVMSDRG-VISGDIILY-DGSARNITEGSTSSYS- 250
Query: 275 LNSDVRGAQRAELIFKDGWIYFVATDGPRANLFRV-NLDGKVERVIRGDRSV-----ESF 328
+I D ++ + D FR+ NLD E + G +V SF
Sbjct: 251 -----------HVILCDNAVFALEND---RTTFRIRNLDSG-EIIWSGMGAVYPVYSPSF 295
Query: 329 S-VGDYIAFTAQDATTPTELYALRDGKEKRITDFNAWIRDYKLSKPEHFRVTASDGKEID 387
D AF P E++ LRD + K + N+ + E A DG+++
Sbjct: 296 DHAADAFAFAFSSPADPPEIHLLRDAETK--SSINSHLDGVSPYPAEIVEWKAKDGEDLY 353
Query: 388 AWIMKPVDFKPGRKYPAVLEIHGGPKTAYGYA-FMHEFQVLVAKGFVVIFSNPRGSDGYG 446
I++ +D K P ++ IHGGP T++ YA F+ + + GF V N RGS G G
Sbjct: 354 G-ILRLID----PKNPLIVYIHGGP-TSFSYASFLDRTSIYLGYGFNVFAPNYRGSVGKG 407
Query: 447 EEFADIR-GHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVGHTNRF 505
+A++ G G +D+ D++ + E LK I +R+ +TGGSYGG+M+ V T+ F
Sbjct: 408 RRYAELNVGDLGGKDFDDVISGI-EFLKNTGKIATDRIYITGGSYGGYMSALAVMKTDIF 466
Query: 506 KAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPWSNLEGYWEKSPLKYAPNVETPLLII 565
+A+V+ IS+W+SF G +++ + + + DPW+ + Y E SP++ +TP L++
Sbjct: 467 RASVSLFGISDWVSFHGVSNL-HLWDRLHMDADPWA-FKKYDEYSPIRIMHEPKTPTLLM 524
Query: 566 HSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENH 602
H +D + + +FY LK V + +FP E H
Sbjct: 525 HGIKDPYVPIGQYYEFYRFLKEKNCEVRMIVFPREGH 561
>gb|AAD41777.1|AF125190_1 (AF125190) alanyl dipeptidyl peptidase [Aspergillus oryzae]
Length = 725
Score = 124 bits (309), Expect = 2e-27
Identities = 77/250 (30%), Positives = 126/250 (49%), Gaps = 12/250 (4%)
Query: 385 EIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAY--GYAFMHEFQVLVAKGFVVIFSNPRGS 442
+I A+++ P +F + YP + IHGGP++++ ++ +V +G+VV+ NP GS
Sbjct: 456 KIQAFVIYPENFDKSKSYPLLYYIHGGPQSSWLDSWSTRWNPKVFADQGYVVVAPNPTGS 515
Query: 443 DGYGEEFAD-IRGHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVGH 501
G+G+ D I+ +G Y+DL++ + + FDFID + G SYGGFM NWI G
Sbjct: 516 SGFGDALQDAIQNQWGGYPYEDLVKGWEYVNENFDFIDTDNGVAAGASYGGFMINWIQGS 575
Query: 502 T--NRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPWSNLEGY--WEKSPLKYAPN 557
+FKA V+ + T ++ +F + G W N E Y W+ S +
Sbjct: 576 DLGRKFKALVSHDGTFVADAKVSTEEL--WFMQHEFNGTFWDNRENYRRWDPSAPERILK 633
Query: 558 VETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDLSRSGRPKHRVKRL 617
TP+LIIHS DYR + E L + L+ G FP ENH + ++ +
Sbjct: 634 FSTPMLIIHSDLDYRLPVSEGLSLFNILQERGVPSRFLNFPDENHWVQNK---ENSLVWH 690
Query: 618 ELIVGWFERW 627
+ ++GW ++
Sbjct: 691 QQVLGWLNKY 700
>gb|AAD52012.1|AF082514_1 (AF082514) Tri r 4 allergen [Trichophyton rubrum]
Length = 726
Score = 121 bits (301), Expect = 2e-26
Identities = 93/353 (26%), Positives = 158/353 (44%), Gaps = 27/353 (7%)
Query: 294 IYFVATDGPRANLFRVNLDGKVER---VIRGDRSVESFSV--GDYIAFTAQDATTPTELY 348
+Y A D LF + D + V++ D SV SF + ++ LY
Sbjct: 351 LYVTAEDHATGKLFTLPADARDNHKPAVVKHDGSVSSFYFIGSSKSVLISGNSLWSNALY 410
Query: 349 --ALRDGKEKRITDFNAWIRDYKLSKPEHFRVTASDGK--EIDAWIMKPVDFKPGRKYPA 404
A D +++ N + K P DG +I +WI+KP F + YP
Sbjct: 411 QVATPDRPNRKLFYANEHDPELKGLGPNDIEPLWVDGARTKIHSWIVKPTGFDKNKVYPL 470
Query: 405 VLEIHGGPKTAYGYAFMHEF--QVLVAKGFVVIFSNPRGSDGYGEEFAD-IRGHYGERDY 461
IHGGP+ ++G + + +V +G+VV+ NP GS G+G++ D I +G Y
Sbjct: 471 AFLIHGGPQGSWGDNWSTRWNPRVWADQGYVVVAPNPTGSTGFGQKLTDDITNDWGGAPY 530
Query: 462 QDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVGHT--NRFKAAVTQRSISNWIS 519
+DL+++ + +ID + G S+GGFM NWI G +FKA V+ +
Sbjct: 531 KDLVKIWEHVHDHIKYIDTDNGIAAGASFGGFMVNWIQGQDLGRKFKALVSHDG-----T 585
Query: 520 FFGTTDIG---YYFAPDQIGGDPWSNLEGY--WEKSPLKYAPNVETPLLIIHSTEDYRCW 574
F G++ IG +F G + + Y W+ S + TP L++H+ D+R
Sbjct: 586 FVGSSKIGTDELFFIEHDFNGTFFEARQNYDRWDCSKPELVAKWSTPQLVVHNDFDFRLS 645
Query: 575 LPEALQFYIALKYLGKTVELAIFPGENHDLSRSGRPKHRVKRLELIVGWFERW 627
+ E + + L+ G FP E H ++ +P++ + + ++GW +W
Sbjct: 646 VAEGVGLFNVLQEKGVPSRFLNFPDETHWVT---KPENSLVWHQQVLGWVNKW 695
>pir||T09631 probable acylaminoacyl-peptidase (EC 3.4.19.1) - Aspergillus
fumigatus >gi|2340046|gb|AAB67282.1| (L48074) secreted
dipeptidyl peptidase [Aspergillus fumigatus]
Length = 721
Score = 120 bits (298), Expect = 5e-26
Identities = 74/250 (29%), Positives = 123/250 (48%), Gaps = 12/250 (4%)
Query: 385 EIDAWIMKPVDFKPGRKYPAVLEIHGGPKT--AYGYAFMHEFQVLVAKGFVVIFSNPRGS 442
+I AW++ P +F +KYP + IHGGP+ A G++ + +G+VV+ NP GS
Sbjct: 453 DIHAWVIYPENFDKSKKYPLIFFIHGGPQGNWADGWSTRWNPKAWADQGYVVVAPNPTGS 512
Query: 443 DGYGEEFAD-IRGHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVGH 501
G+G+ I+ ++G Y DL++ + + D++D + G SYGGFM NWI G
Sbjct: 513 TGFGQALTTAIQNNWGGAPYDDLVKCWEYVHENLDYVDTDHGVAAGASYGGFMINWIQGS 572
Query: 502 T--NRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPWSNLEGY--WEKSPLKYAPN 557
+FKA V+ + T ++ +F + G W + Y W+ S +
Sbjct: 573 PLGRKFKALVSHDGTFVADAKVSTEEL--WFMQREFNGTFWDARDNYRRWDPSAPERILQ 630
Query: 558 VETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDLSRSGRPKHRVKRL 617
TP+L+IHS +DYR + E L + L+ G FP ENH + P++ +
Sbjct: 631 FATPMLVIHSDKDYRLPVAEGLSLFNVLQERGVPSRFLNFPDENHWVV---NPENSLVWH 687
Query: 618 ELIVGWFERW 627
+ +GW ++
Sbjct: 688 QQALGWINKY 697
>gi|6978513 n-acylaminoacyl-peptide hydrolase [Rattus norvegicus]
>gi|113178|sp|P13676|ACPH_RAT ACYLAMINO-ACID-RELEASING
ENZYME (ACYL-PEPTIDE HYDROLASE) (APH)
(ACYLAMINOACYL-PEPTIDASE) >gi|91923|pir||S07624
acylaminoacyl-peptidase (EC 3.4.19.1) - rat
>gi|202932|gb|AAA88506.1| (J04733) acyl-peptide
hydrolase [Rattus norvegicus]
Length = 732
Score = 118 bits (292), Expect = 2e-25
Identities = 72/231 (31%), Positives = 125/231 (53%), Gaps = 13/231 (5%)
Query: 385 EIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAYGYAFMHEFQVLVAKGFVVIFSNPRGSDG 444
+ +A +++P + + P V+ HGGP +++ A+M +L GF V+ N RGS G
Sbjct: 483 DFEAILLQPSNPPDKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGSTG 542
Query: 445 YGEE-FADIRGHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVG-HT 502
+G++ + G+ G +D +D+ V++ L+ F D R+ + GGS+GGF++ ++G +
Sbjct: 543 FGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHF-DARRVALMGGSHGGFLSCHLIGQYP 601
Query: 503 NRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPWSNL--------EGYWEKSPLKY 554
+ A + + + N S G+TDI + + G P+SN E +KSP+KY
Sbjct: 602 ETYSACIARNPVINIASMMGSTDIPDWCMVET--GFPYSNSCLPDLNVWEEMLDKSPIKY 659
Query: 555 APNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDLS 605
P V+TP+L++ ED R + +++Y ALK V L ++P NH LS
Sbjct: 660 IPQVKTPVLLMLGQEDRRVPFKQGMEYYRALKARNVPVRLLLYPKSNHALS 710
>pir||JU0132 acylaminoacyl-peptidase (EC 3.4.19.1) [validated] - pig
>gi|1332717|gb|AAB36056.1| acylamino acid-releasing
enzyme, AARE {EC 3.4.19.1} [swine, liver, Peptide, 732
aa] >gi|1583737|prf||2121361A acyl-AA releasing enzyme
[Sus scrofa domestica]
Length = 732
Score = 116 bits (289), Expect = 6e-25
Identities = 72/234 (30%), Positives = 126/234 (53%), Gaps = 15/234 (6%)
Query: 383 GKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAYGYAFMHEFQVLVAKGFVVIFSNPRGS 442
G + +A +++P + + P V+ HGGP +++ A+M +L GF V+ N RGS
Sbjct: 481 GLDFEAILLQPSNSPEKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGS 540
Query: 443 DGYGEE-FADIRGHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVG- 500
G+G++ + G+ G +D +D+ V++ L+ F D R+ + GGS+GGF++ ++G
Sbjct: 541 TGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHF-DAGRVALMGGSHGGFLSCHLIGQ 599
Query: 501 HTNRFKAAVTQRSISNWISFFGTTDI--------GYYFAPDQIGG-DPWSNLEGYWEKSP 551
+ + A V + + N S G+TDI G+ ++ D + W+ + +KSP
Sbjct: 600 YPETYSACVVRNPVINIASMMGSTDIPDWCMVEAGFSYSSDCLPDLSVWAAM---LDKSP 656
Query: 552 LKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDLS 605
+KYAP V+TPLL++ ED R + +++Y LK V L ++P H LS
Sbjct: 657 IKYAPQVKTPLLLMLGQEDRRVPFKQGMEYYRVLKARNVPVRLLLYPKSTHALS 710
>sp|P19205|ACPH_PIG ACYLAMINO-ACID-RELEASING ENZYME (ACYL-PEPTIDE HYDROLASE) (APH)
(ACYLAMINOACYL-PEPTIDASE) >gi|217672|dbj|BAA00411.1|
(D00524) acylamino acid-releasing enzyme [Sus scrofa]
Length = 732
Score = 116 bits (289), Expect = 6e-25
Identities = 72/234 (30%), Positives = 126/234 (53%), Gaps = 15/234 (6%)
Query: 383 GKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAYGYAFMHEFQVLVAKGFVVIFSNPRGS 442
G + +A +++P + + P V+ HGGP +++ A+M +L GF V+ N RGS
Sbjct: 481 GLDFEAILLQPSNSPEKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGS 540
Query: 443 DGYGEE-FADIRGHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVG- 500
G+G++ + G+ G +D +D+ V++ L+ F D R+ + GGS+GGF++ ++G
Sbjct: 541 TGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHF-DAGRVALMGGSHGGFLSCHLIGQ 599
Query: 501 HTNRFKAAVTQRSISNWISFFGTTDI--------GYYFAPDQIGG-DPWSNLEGYWEKSP 551
+ + A V + + N S G+TDI G+ ++ D + W+ + +KSP
Sbjct: 600 YPETYSACVVRNPVINIASMMGSTDIPDWCMVEAGFSYSSDCLPDLSVWAAM---LDKSP 656
Query: 552 LKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDLS 605
+KYAP V+TPLL++ ED R + +++Y LK V L ++P H LS
Sbjct: 657 IKYAPQVKTPLLLMLGQEDRRVPFKQGMEYYRVLKARNVPVRLLLYPKSTHALS 710
>emb|CAA33040.1| (X14915) acyl-peptide hydrolase [Rattus norvegicus]
Length = 729
Score = 115 bits (285), Expect = 2e-24
Identities = 71/231 (30%), Positives = 123/231 (52%), Gaps = 16/231 (6%)
Query: 385 EIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAYGYAFMHEFQVLVAKGFVVIFSNPRGSDG 444
+ +A +++P + + P V+ HGGP +++ A+M +L GF V+ N RGS G
Sbjct: 483 DFEAILLQPSNPPDKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGSTG 542
Query: 445 YGEE-FADIRGHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVG-HT 502
+G++ + G+ G +D +D+ V++ L+ F D R+ + GGS+GGF++ ++G +
Sbjct: 543 FGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHF-DARRVALMGGSHGGFLSCHLIGQYP 601
Query: 503 NRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPWSNL--------EGYWEKSPLKY 554
+ A + + + N S G+TD+ G P+SN E +KSP+KY
Sbjct: 602 ETYSACIARNPVINIASMMGSTDMCMVET-----GFPYSNSCLPDLNVWEEMLDKSPIKY 656
Query: 555 APNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDLS 605
P V+TP+L++ ED R + +++Y ALK V L ++P NH LS
Sbjct: 657 IPQVKTPVLLMLGQEDRRVPFKQGMEYYRALKARNVPVRLLLYPKSNHALS 707
>gi|9951917 N-acylaminoacyl-peptide hydrolase; oxidized protein hydrolase;
acylaminoacyl-peptidase [Homo sapiens]
>gi|1703089|sp|P13798|ACPH_HUMAN
ACYLAMINO-ACID-RELEASING ENZYME (ACYL-PEPTIDE HYDROLASE)
(APH) (ACYLAMINOACYL-PEPTIDASE) (DNF15S2 PROTEIN)
>gi|2118063|pir||JC4655 acylaminoacyl-peptidase (EC
3.4.19.1) - human >gi|556514|dbj|BAA07476.1| (D38441)
acylamino acid-releasing enzyme [Homo sapiens]
Length = 732
Score = 114 bits (283), Expect = 3e-24
Identities = 71/234 (30%), Positives = 125/234 (53%), Gaps = 15/234 (6%)
Query: 383 GKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAYGYAFMHEFQVLVAKGFVVIFSNPRGS 442
G + +A +++P + P V+ HGGP +++ A+M +L GF V+ N RGS
Sbjct: 481 GLDFEAILLQPGSPPDKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGS 540
Query: 443 DGYGEE-FADIRGHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVG- 500
G+G++ + G+ G +D +D+ V++ L+ F D + + GGS+GGF++ ++G
Sbjct: 541 TGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHF-DASHVALMGGSHGGFISCHLIGQ 599
Query: 501 HTNRFKAAVTQRSISNWISFFGTTDI--------GYYFAPDQIGG-DPWSNLEGYWEKSP 551
+ ++A V + + N S G+TDI G+ F+ D + W+ + +KSP
Sbjct: 600 YPETYRACVARNPVINIASMLGSTDIPDWCVVEAGFPFSSDCLPDLSVWAEM---LDKSP 656
Query: 552 LKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDLS 605
++Y P V+TPLL++ ED R + +++Y ALK V L ++P H LS
Sbjct: 657 IRYIPQVKTPLLLMLGQEDRRVPFKQGMEYYRALKTRNVPVRLLLYPKSTHALS 710
>gb|AAF37321.1|AF141383_1 (AF141383) oxidized protein hydrolase [Homo sapiens]
Length = 732
Score = 114 bits (283), Expect = 3e-24
Identities = 71/234 (30%), Positives = 125/234 (53%), Gaps = 15/234 (6%)
Query: 383 GKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAYGYAFMHEFQVLVAKGFVVIFSNPRGS 442
G + +A +++P + P V+ HGGP +++ A+M +L GF V+ N RGS
Sbjct: 481 GLDFEAILLQPGSPPDKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGS 540
Query: 443 DGYGEE-FADIRGHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVG- 500
G+G++ + G+ G +D +D+ V++ L+ F D + + GGS+GGF++ ++G
Sbjct: 541 TGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHF-DASHVALMGGSHGGFISCHLIGQ 599
Query: 501 HTNRFKAAVTQRSISNWISFFGTTDI--------GYYFAPDQIGG-DPWSNLEGYWEKSP 551
+ ++A V + + N S G+TDI G+ F+ D + W+ + +KSP
Sbjct: 600 YPETYRACVARNPVINIASMLGSTDIPDWCVVEAGFPFSSDCLPDLSVWAEM---LDKSP 656
Query: 552 LKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDLS 605
++Y P V+TPLL++ ED R + +++Y ALK V L ++P H LS
Sbjct: 657 IRYIPQVKTPLLLMLGQEDRRVPFKQGMEYYRALKTRNVPVRLLLYPKSTHALS 710
>gi|11431488 N-acylaminoacyl-peptide hydrolase [Homo sapiens]
Length = 732
Score = 114 bits (283), Expect = 3e-24
Identities = 71/234 (30%), Positives = 125/234 (53%), Gaps = 15/234 (6%)
Query: 383 GKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAYGYAFMHEFQVLVAKGFVVIFSNPRGS 442
G + +A +++P + P V+ HGGP +++ A+M +L GF V+ N RGS
Sbjct: 481 GLDFEAILLQPGSPPDKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGS 540
Query: 443 DGYGEE-FADIRGHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVG- 500
G+G++ + G+ G +D +D+ V++ L+ F D + + GGS+GGF++ ++G
Sbjct: 541 TGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHF-DASHVALMGGSHGGFISCHLIGQ 599
Query: 501 HTNRFKAAVTQRSISNWISFFGTTDI--------GYYFAPDQIGG-DPWSNLEGYWEKSP 551
+ ++A V + + N S G+TDI G+ F+ D + W+ + +KSP
Sbjct: 600 YPETYRACVARNPVINIASMLGSTDIPDWCVVEAGFPFSSDCLPDLSVWAEM---LDKSP 656
Query: 552 LKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDLS 605
++Y P V+TPLL++ ED R + +++Y ALK V L ++P H LS
Sbjct: 657 IRYIPQVKTPLLLMLGQEDRRVPFKQGMEYYRALKTRNVPVRLLLYPKSTHALS 710
>gb|AAC46184.1| (AF026511) dipeptidyl peptidase IV [Porphyromonas gingivalis]
Length = 723
Score = 109 bits (271), Expect = 7e-23
Identities = 152/644 (23%), Positives = 270/644 (41%), Gaps = 82/644 (12%)
Query: 13 FKLVGNLDAS--GKKVVFQVTEISIKENDYFSSIYLYDGRKVRRFTFGR---KDANPRFS 67
FK + N + S G ++ SI + Y +++Y YD R+ K P FS
Sbjct: 89 FKQIQNYEVSSTGHHILLFTDMESIYRHSYRAAVYDYDVRRNLVKPLSEHVGKVMIPTFS 148
Query: 68 PDGRLIAFTSKRS----KEGRESELYLMPVDG-------GEARLLAKFKYGIKDLR-FSE 115
PDGR++AF + K ++E+ + DG G + + ++G+ +L +S
Sbjct: 149 PDGRMVAFVRDNNIFIKKFDFDTEVQVT-TDGQINSILNGATDWVYEEEFGVTNLMSWSA 207
Query: 116 DGKEIAVITPVEVKKVANEKEDVHVIDEIPFWFNGIGWIYGRRNA---LYLVDVESGKKR 172
D +A + E V + ++ P + G +N+ L+L +V +
Sbjct: 208 DNAFLAFVRSDE-SAVPEYRMPMYEDKIYPEDYTYKYPKAGEKNSTVSLHLYNVADRNTK 266
Query: 173 KVS---------PR-----NLDVLSV----RFHNG-KLYLLAQEDREKKPMISDVYVLEG 213
VS PR N D L+V R N K+Y + + K ++ D+
Sbjct: 267 SVSLPIDADGYIPRIAFTDNADELAVMTLNRLQNDFKMYYVHPKSLVAKLILQDMN---- 322
Query: 214 KRVKKLTPGKWRILDFVPLSDGLILKANTLERGFATTTSIYLYRNGELRRLFKEDLSAYN 273
K+ W + + + G + + GFA IYLY N + + +++ N
Sbjct: 323 ---KRYVDSDW--IQALKFTAGGGFAYVSEKDGFA---HIYLYDN---KGVMHRRITSGN 371
Query: 274 SLNSDVRGAQRAELIFKDGWIYFVATDGP-RANLFRVNLDGKVERVIRGDRSVESFSVGD 332
+ + G + +F Y A + P R ++ ++ G+ ++ + ++ G+
Sbjct: 372 WDVTKLYGVDASGTVF-----YQSAEESPIRRAVYAIDAKGRKTKLSLNVGTNDALFSGN 426
Query: 333 YIAF--TAQDATTPT--ELYALRDGKEKRITDFNAWIRD----YKLSKPEHFRVTASDGK 384
Y + T A TPT ++ +D KE R + N +R+ Y+ + E + G
Sbjct: 427 YAYYINTYSSAATPTVVSVFRSKDAKELRTLEDNVALRERLKAYRYNPKEFTIIKTQSGL 486
Query: 385 EIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAY---GYAFMHEFQVLVAKGFVVIFSNPRG 441
E++AWI+KP+DF P R YP ++ + GP + Y+F E L +KG+VV + RG
Sbjct: 487 ELNAWIVKPIDFDPSRHYPVLMVQYSGPNSQQVLDRYSFDWE-HYLASKGYVVACVDGRG 545
Query: 442 SDGYGEEFADIRGHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVGH 501
+ GEE+ D A+ + ++D R+G+ G SYGG+ T +
Sbjct: 546 TGARGEEWRKCTYMQLGVFESDDQIAAATAIGQLPYVDAARIGIWGWSYGGYTTLMSLCR 605
Query: 502 TN-RFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPWSNLEGYWEKSPLKYAPNVET 560
N FKA + +++W F+ + ++ P N GY S L A ++
Sbjct: 606 GNGTFKAGIAVAPVADW-RFYDSV------YTERFMRTPKENASGYKMSSALDVASQLQG 658
Query: 561 PLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDL 604
LLI+ + D L + F AL ++AI+ +NH +
Sbjct: 659 NLLIVSGSADDNVHLQNTMLFTEALVQANIPFDMAIYMDKNHSI 702
>gb|AAC35353.1| (AF083393) outer membrane protein adhesin [Capnocytophaga
gingivalis]
Length = 237
Score = 109 bits (270), Expect = 9e-23
Identities = 65/235 (27%), Positives = 115/235 (48%), Gaps = 14/235 (5%)
Query: 376 FRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAYGYAFMHEFQ-----VLVAK 430
F +T +G +++AW++KP DF +KYP ++ + GP + + F +L K
Sbjct: 1 FXLTTKNGDKLNAWMIKPSDFNENKKYPLLMFQYSGPGSQQVHNSFSGFDTFWYYMLAQK 60
Query: 431 GFVVIFSNPRGSDGYGEEFADIR-GHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGS 489
G++V+ + RG+ G F G+ + +D +E + + + +ID++R+G+ G S
Sbjct: 61 GYIVLCVDGRGTGYKGAAFKKCTYKQLGKYELEDQVEAA-KIVGNYKYIDKDRIGIWGWS 119
Query: 490 YGGFMTNWIVGHTNRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPWSNLEGYWEK 549
+GGFM + + FK ++ ++NW F+ T Y P N EGY
Sbjct: 120 FGGFMASNCILRGEMFKMSIAVAPVTNW-RFYDTVYTERYMQT------PQENPEGYDNN 172
Query: 550 SPLKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDL 604
SPL YA N+ L++H T D + +++ + K E AI+P +NH +
Sbjct: 173 SPLTYAKNLNKKFLLVHGTADDNVHVQNSMRLIESFVQYDKQFEWAIYPDKNHGI 227
>pir||H72474 probable acylamino-acid-releasing enzyme APE2441 - Aeropyrum pernix
(strain K1) >gi|5106145|dbj|BAA81456.1| (AP000064) 591aa
long hypothetical acylamino-acid-releasing enzyme
[Aeropyrum pernix]
Length = 591
Score = 106 bits (263), Expect = 6e-22
Identities = 134/504 (26%), Positives = 217/504 (42%), Gaps = 52/504 (10%)
Query: 128 VKKVANEKEDVHVIDEIPFWFNG--IGWIYGRRNA----LYLVDVESGKKRKVSPRNLDV 181
V+ VA E +++I P+ +G + + +RN LY+ D E G V +
Sbjct: 89 VRLVAGEDGSINMIG--PWSPDGRLLAFTSNKRNGVDFDLYVFDREKGSVSIVVEGEGII 146
Query: 182 LSVRFHNGKLYLLAQEDREKKPMISDVYVLEGKRVKKLTPGKWRILDFVP--LSDGLILK 239
+ + +G L + + I V V +G+ K LT + L+ P + G L
Sbjct: 147 AASSWIDGSRLLAVKRNSNLDSDILAVNVYKGE-AKVLTRHRGEELNTSPRPIGGGKALF 205
Query: 240 ANTLERGFATTTSIYLYRNGELRRLFKE--DLSAYNSLNSDVRGAQRAELIFKDGWIYFV 297
+ ++ F I L + G+ R +F+E D+ A V +Y +
Sbjct: 206 ISNMDSEFTGIALIDL-QTGDRRLVFREQWDVEALEVSGKTV--------------VYSL 250
Query: 298 ATDGPRANLFRVNLDGK--------VERVIRGDRSVESFSVGDYIAFTAQDATTPT---E 346
DG + ++ +D + +E + RG S+ S + + + +TP E
Sbjct: 251 NVDG-ESRVYTTKIDERGSLLQPRPIEGLPRG--SLLSLDLNEKLGLAVFSLSTPKHGIE 307
Query: 347 LYALRDGKE-KRIT-DFNAWIRDYKLSKPEHFRVTASDGKEIDAWIMKPVDFKPGRKYPA 404
+Y G+ R+T AW+R+ + +PEHF + DG ++ A + KP D PA
Sbjct: 308 IYIAGLGRSASRLTVSPKAWLREDEFVEPEHFSYESFDGIKVRALLYKP-DKPLYTPPPA 366
Query: 405 VLEIHGGPKTAYGYAFMHEFQVLVAKGFVVIFSNPRGSDGYGEEFADIRGHYGERD-YQD 463
V+ +HGGP++ F Q L A G I N RGS GYG F + D +D
Sbjct: 367 VVYLHGGPESQERVRFNVFPQALAAIGIATIAPNYRGSTGYGRRFVHLDDVEKRMDAVRD 426
Query: 464 LMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVG-HTNRFKAAVTQRSISNWISFFG 522
+ V A++ +D RL V GGSYGG++T + + + +K V I N ++F
Sbjct: 427 VYYAVKAAVEA-GLVDGSRLCVMGGSYGGYLTLMSLAIYPDLWKCGVEIVGIVNLVTFIR 485
Query: 523 TTDIGYYFAPDQIG--GDPWSNLEGYWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQ 580
T Y +I GDP + E + SP+ Y N++ PL++IH +D R + EA Q
Sbjct: 486 NT--SPYRRRYRIAEYGDPDVHGEIMLKLSPITYVENMKAPLMVIHGAKDPRVPVSEAEQ 543
Query: 581 FYIALKYLGKTVELAIFPGENHDL 604
AL G V E H +
Sbjct: 544 LVEALSSRGVRVRYVRLEDEGHGI 567
>dbj|BAA28265.1| (AB008194) DPP IV [Porphyromonas gingivalis]
Length = 723
Score = 106 bits (262), Expect = 8e-22
Identities = 151/644 (23%), Positives = 267/644 (41%), Gaps = 82/644 (12%)
Query: 13 FKLVGNLDAS--GKKVVFQVTEISIKENDYFSSIYLYDGRKVRRFTFGR---KDANPRFS 67
FK + N + S G ++ SI + Y +++Y YD R+ K P FS
Sbjct: 89 FKQIQNYEVSSTGHHILLFTDMESIYRHSYRAAVYDYDVRRNLVKPLSEHVGKVMIPTFS 148
Query: 68 PDGRLIAFTSKRS----KEGRESELYLMPVDG-------GEARLLAKFKYGIKDLR-FSE 115
PDGR++AF + K ++E+ + DG G + + ++G+ +L +S
Sbjct: 149 PDGRMVAFVRDNNIFIKKFDFDTEVQVT-TDGQINSILNGATDWVYEEEFGVTNLMSWSA 207
Query: 116 DGKEIAVITPVEVKKVANEKEDVHVIDEIPFWFNGIGWIYGRRNA---LYLVDVESGKKR 172
D +A + E V + ++ P + G +N+ L+L +V +
Sbjct: 208 DNAFLAFVRSDE-SAVPEYRMPMYEDKLYPEDYTYKYPKAGEKNSTVSLHLYNVADRNTK 266
Query: 173 KVS---------PR-----NLDVLSV----RFHNG-KLYLLAQEDREKKPMISDVYVLEG 213
VS PR N D L+V R N K+Y + + K ++ D+
Sbjct: 267 SVSLPIDADGYIPRIAFTDNADELAVMTLNRLQNDFKMYYVHPKSLVPKLILQDMN---- 322
Query: 214 KRVKKLTPGKWRILDFVPLSDGLILKANTLERGFATTTSIYLYRNGELRRLFKEDLSAYN 273
K+ W + + + G + + GFA IYLY N + + +++ N
Sbjct: 323 ---KRYVDSDW--IQTLKFTTGGGFAYVSEKDGFA---HIYLYDN---KGVMHRRITSGN 371
Query: 274 SLNSDVRGAQRAELIFKDGWIYFVATDGP-RANLFRVNLDGKVERVIRGDRSVESFSVGD 332
+ + G + +F Y A + P R ++ ++ G+ ++ + ++ G+
Sbjct: 372 WDVTKLYGVDASGTVF-----YQSAEESPIRRAVYAIDAKGRKTKLSLNVGTNDALFSGN 426
Query: 333 YIAF--TAQDATTPTELYALRD--GKEKRITDFNAWIRD----YKLSKPEHFRVTASDGK 384
Y + T A TP + R KE R + N +R+ Y+ + E + G
Sbjct: 427 YAYYINTYSSAATPAVVSVFRSKGAKELRTLEDNVALRERLKAYRYNPKEFTTIKTQSGL 486
Query: 385 EIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAY---GYAFMHEFQVLVAKGFVVIFSNPRG 441
E++AWI+KP+DF P R YP ++ + GP + Y+F E L +KG+VV + RG
Sbjct: 487 ELNAWIVKPIDFDPSRHYPVLMVQYSGPNSQQVLDRYSFDWE-HYLASKGYVVACVDGRG 545
Query: 442 SDGYGEEFADIRGHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVGH 501
+ GEE+ D A+ + ++D R+G+ G SYGG+ T +
Sbjct: 546 TGARGEEWRKCTYMQLGVFESDDQIAAATAIGQLPYVDAARIGIWGWSYGGYTTLMSLCR 605
Query: 502 TN-RFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPWSNLEGYWEKSPLKYAPNVET 560
N FKA + +++W F+ + ++ P N GY S L A ++
Sbjct: 606 GNGTFKAGIAVAPVADW-RFYDSV------YTERFMRTPKENASGYKMSSALDVASQLQG 658
Query: 561 PLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDL 604
LLI+ + D L + F AL ++AI+ +NH +
Sbjct: 659 NLLIVSGSADDNVHLQNTMLFTEALVQANIPFDMAIYMDKNHSI 702
>gb|AAK42319.1| Acylaminoacyl-peptidase, putative (apeH-2) [Sulfolobus
solfataricus]
Length = 569
Score = 104 bits (256), Expect = 4e-21
Identities = 81/279 (29%), Positives = 136/279 (48%), Gaps = 25/279 (8%)
Query: 330 VGDYIAFTAQDATTPTELYAL-RDGKEKRITDFNAWIRDYKLSKPEHFRVTASDGKEIDA 388
+GD I F+ +P ++Y + R GK + + D R + + E+ +V E+
Sbjct: 285 IGDEIYFSHSSLVSPHKIYKVSRYGKIEVVVDN----RKVDVGEVEYVKVKTD--VEVPT 338
Query: 389 WIMKPVDFKPGRKYPA--VLEIHGGPKTAYGYAFMHEFQVLVAKGFVVIFSNPRGSDGYG 446
W++K RK P ++ IHGGP + ++ LV G+ VI N RGS GYG
Sbjct: 339 WVIK-------RKIPGNTIIYIHGGPWSEVDNSWNLLIAPLVLAGYNVIAPNYRGSTGYG 391
Query: 447 EEFADIR-GHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVG-HTNR 504
+F + G G D +D+++V D A++ ++G+ G SYGG+MT VG ++
Sbjct: 392 SKFMFMNIGDAGGGDLRDVVKVRDYAIETGI---TNKVGIMGYSYGGYMTLLAVGKEPDK 448
Query: 505 FKAAVTQRSISNWISFFGTTDIGYY-FAPDQIGGDPWSNLEGYWEKSPLKYAPNVETPLL 563
+ + ++++W+ + +D + F G N++ E+SP+ Y NV+ PL
Sbjct: 449 WDFGIAGAAVADWVEMYDLSDSLFRGFMEILFNG---KNIDLMKERSPITYVRNVKVPLC 505
Query: 564 IIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENH 602
IIHS D R L +++ L+ GKT E + P H
Sbjct: 506 IIHSQNDTRTPLNPVMRYIQELQRTGKTYEFHVIPNLGH 544
>pir||S74053 probable acylaminoacyl-peptidase (EC 3.4.19.1) - Sulfolobus
solfataricus >gi|1707747|emb|CAA69467.1| (Y08256)
acylamino-acid-releasing enzyme [Sulfolobus
solfataricus]
Length = 569
Score = 104 bits (256), Expect = 4e-21
Identities = 81/279 (29%), Positives = 136/279 (48%), Gaps = 25/279 (8%)
Query: 330 VGDYIAFTAQDATTPTELYAL-RDGKEKRITDFNAWIRDYKLSKPEHFRVTASDGKEIDA 388
+GD I F+ +P ++Y + R GK + + D R + + E+ +V E+
Sbjct: 285 IGDEIYFSHSSLVSPHKIYKVSRYGKIEVVVDN----RKVDVGEVEYVKVKTD--VEVPT 338
Query: 389 WIMKPVDFKPGRKYPA--VLEIHGGPKTAYGYAFMHEFQVLVAKGFVVIFSNPRGSDGYG 446
W++K RK P ++ IHGGP + ++ LV G+ VI N RGS GYG
Sbjct: 339 WVIK-------RKIPGNTIIYIHGGPWSEVDNSWNLLIAPLVLAGYNVIAPNYRGSTGYG 391
Query: 447 EEFADIR-GHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVG-HTNR 504
+F + G G D +D+++V D A++ ++G+ G SYGG+MT VG ++
Sbjct: 392 SKFMFMNIGDAGGGDLRDVVKVRDYAIETGI---TNKVGIMGYSYGGYMTLLAVGKEPDK 448
Query: 505 FKAAVTQRSISNWISFFGTTDIGYY-FAPDQIGGDPWSNLEGYWEKSPLKYAPNVETPLL 563
+ + ++++W+ + +D + F G N++ E+SP+ Y NV+ PL
Sbjct: 449 WDFGIAGAAVADWVEMYDLSDSLFRGFMEILFNG---KNIDLMKERSPITYVRNVKVPLC 505
Query: 564 IIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENH 602
IIHS D R L +++ L+ GKT E + P H
Sbjct: 506 IIHSQNDTRTPLNPVMRYIQELQRTGKTYEFHVIPNLGH 544
>gb|AAF56356.1| (AE003749) CG3744 gene product [alt 1] [Drosophila melanogaster]
Length = 1102
Score = 98.7 bits (242), Expect = 2e-19
Identities = 72/242 (29%), Positives = 115/242 (46%), Gaps = 17/242 (7%)
Query: 373 PEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKT-AYGYAFMHEFQ----VL 427
P+ F G + A + KP +F+ G KYP VL ++GGP+ F + Q +L
Sbjct: 848 PQIFSPQLPSGDIVYAMVFKPHNFELGVKYPTVLNVYGGPEVQTVNNTFKGKHQLRMHML 907
Query: 428 VAKGFVVIFSNPRGSDGYGEEF-ADIRGHYGERDYQDLMEVVDEALKRFDFIDEERLGVT 486
A+G+ VI + RGS G+ F + IRG G+ + D ++ + + +ID +R+ +
Sbjct: 908 AAQGYCVICIDSRGSRHRGKRFESHIRGRMGQVELTDQVDALRSLSDQLGYIDMDRVAIH 967
Query: 487 GGSYGGFMT-NWIVGHTNRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPWSNLEG 545
G SYGG+++ +V + FK A+ ++NW + D GY ++ P +N G
Sbjct: 968 GWSYGGYLSLMGLVQYPKIFKVAIAGAPVTNWEYY----DTGY---TERYMDMPQNNEAG 1020
Query: 546 YWEKSPLKYA---PNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENH 602
Y S L+Y P + LL+IH D + AL K E+ +FP E H
Sbjct: 1021 YSAGSVLEYVNSFPEEDKRLLLIHGLIDENVHFCHTSRLISALNKANKPYEVHLFPEERH 1080
Query: 603 DL 604
L
Sbjct: 1081 SL 1082
>gb|AAF56357.1| (AE003749) CG3744 gene product [alt 2] [Drosophila melanogaster]
Length = 1042
Score = 98.7 bits (242), Expect = 2e-19
Identities = 72/242 (29%), Positives = 115/242 (46%), Gaps = 17/242 (7%)
Query: 373 PEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKT-AYGYAFMHEFQ----VL 427
P+ F G + A + KP +F+ G KYP VL ++GGP+ F + Q +L
Sbjct: 788 PQIFSPQLPSGDIVYAMVFKPHNFELGVKYPTVLNVYGGPEVQTVNNTFKGKHQLRMHML 847
Query: 428 VAKGFVVIFSNPRGSDGYGEEF-ADIRGHYGERDYQDLMEVVDEALKRFDFIDEERLGVT 486
A+G+ VI + RGS G+ F + IRG G+ + D ++ + + +ID +R+ +
Sbjct: 848 AAQGYCVICIDSRGSRHRGKRFESHIRGRMGQVELTDQVDALRSLSDQLGYIDMDRVAIH 907
Query: 487 GGSYGGFMT-NWIVGHTNRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPWSNLEG 545
G SYGG+++ +V + FK A+ ++NW + D GY ++ P +N G
Sbjct: 908 GWSYGGYLSLMGLVQYPKIFKVAIAGAPVTNWEYY----DTGY---TERYMDMPQNNEAG 960
Query: 546 YWEKSPLKYA---PNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENH 602
Y S L+Y P + LL+IH D + AL K E+ +FP E H
Sbjct: 961 YSAGSVLEYVNSFPEEDKRLLLIHGLIDENVHFCHTSRLISALNKANKPYEVHLFPEERH 1020
Query: 603 DL 604
L
Sbjct: 1021 SL 1022
>gb|AAG29766.1|AF221634_1 (AF221634) dipeptidyl peptidase 8 [Homo sapiens]
Length = 882
Score = 96.3 bits (236), Expect = 9e-19
Identities = 73/257 (28%), Positives = 120/257 (46%), Gaps = 19/257 (7%)
Query: 358 ITDFNAWIRDYKLSKPEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEIHGGPK---- 413
I D + DY + PE F ++ G + + KP D +PG+KYP VL I+GGP+
Sbjct: 604 ILDSAGPLPDY--TPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLV 661
Query: 414 -TAYGYAFMHEFQVLVAKGFVVIFSNPRGSDGYGEEF-ADIRGHYGERDYQDLMEVVDEA 471
+ L + G+VV+ + RGS G +F + G+ + D +E +
Sbjct: 662 NNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYL 721
Query: 472 LKRFDFIDEERLGVTGGSYGGFMTNW-IVGHTNRFKAAVTQRSISNWISFFGTTDIGYYF 530
R+DFID +R+G+ G SYGG+++ ++ ++ F+ A+ ++ WI + D GY
Sbjct: 722 ASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFY----DTGY-- 775
Query: 531 APDQIGGDPWSNLEGYWEKSPLKYA---PNVETPLLIIHSTEDYRCWLPEALQFYIALKY 587
++ G P N +GY+ S A P+ LL++H D L
Sbjct: 776 -TERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVR 834
Query: 588 LGKTVELAIFPGENHDL 604
GK +L I+P E H +
Sbjct: 835 AGKPYDLQIYPQERHSI 851
>pir||S66261 X-Pro dipeptidyl-peptidase (EC 3.4.14.11) - Flavobacterium
meningosepticum >gi|577284|dbj|BAA07702.1| (D42121)
Dipeptidyl peptidase IV [Chryseobacterium
meningosepticum] >gi|1098018|prf||2115194A dipeptidyl
peptidase IV [Flavobacterium meningosepticum]
Length = 711
Score = 92.8 bits (227), Expect = 1e-17
Identities = 72/298 (24%), Positives = 137/298 (45%), Gaps = 24/298 (8%)
Query: 321 GDRSVESFSVGDYIAFTAQDATTPTELYALRDGKEKRITDF-------NAWIRDYKLSKP 373
G+ S +Y T+ A PT+ Y L+D K + + N D ++K
Sbjct: 403 GNNSAAFSKTFNYFINTSSTAKVPTK-YILKDANGKDVKELQNNDDLLNKLKSDNFIAK- 460
Query: 374 EHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKT-----AYGYAFMHEFQVLV 428
E + + G +++AW++KP +F P +KYP + + GP + ++ F +L
Sbjct: 461 EFITIPNAAGDQMNAWMIKPKNFDPAKKYPVFMFQYSGPGSQQVANSWDGGNGIWFDMLA 520
Query: 429 AKGFVVIFSNPRGSDGYGEEFADIR-GHYGERDYQDLMEVVDEALKRFDFIDEERLGVTG 487
KG++V+ + RG+ G ++ + + G+ + +D + + L ++D+ R+G+ G
Sbjct: 521 QKGYLVVCVDGRGTGFRGTKYKKVTYKNLGKYEIEDQITAA-KWLGNQSYVDKSRIGIFG 579
Query: 488 GSYGGFMTNWIVGH-TNRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPWSNLEGY 546
SYGG+M + + + FK + ++NW F+ + ++ P N +GY
Sbjct: 580 WSYGGYMASLAMTKGADVFKMGIAVAPVTNW-RFYDS------IYTERFLQTPQENKDGY 632
Query: 547 WEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDL 604
SP YA ++ L+IH T D +++F AL K + +P +NH +
Sbjct: 633 DLNSPTTYAKLLKGKFLLIHGTADDNVHFQNSMEFSEALIQNKKQFDFMAYPDKNHSI 690
>pir||JC5142 X-Pro dipeptidyl-peptidase (EC 3.4.14.11) - Xanthomonas maltophilia
>gi|1753197|dbj|BAA11872.1| (D83263) dipeptidyl
peptidase IV [Stenotrophomonas maltophilia]
Length = 741
Score = 90.9 bits (222), Expect = 4e-17
Identities = 84/303 (27%), Positives = 136/303 (44%), Gaps = 35/303 (11%)
Query: 342 TTPTELYALRDGKEKRITDFNAWIRDYK--------LSKPEHF-RVTASDGKE-IDAWIM 391
+TP ++ R EK T + D K +P F +TA+DGK ++ ++
Sbjct: 447 STPPQIELFRANGEKIATLVENDLADPKHPYARYREAQRPVEFGTLTAADGKTPLNYSVI 506
Query: 392 KPVDFKPGRKYPAVLEIHGGPKT-----AYGYAFMHEF-QVLVAKGFVVIFSNPRGSDGY 445
KP F P ++YP + ++GGP + ++ H F Q L +G+VV + RG+
Sbjct: 507 KPAGFDPAKRYPVAVYVYGGPASQTVTDSWPGRGDHLFNQYLAQQGYVVFSLDNRGTPRR 566
Query: 446 GEEFADIRGHYGERDYQDLMEVVDEA-----LKRFDFIDEERLGVTGGSYGGFMTNWIVG 500
G +F YG+ Q +EV D+ LK+ ++D R+GV G S GG+MT ++
Sbjct: 567 GRDFGGAL--YGK---QGTVEVADQLRGVAWLKQQPWVDPARIGVQGWSNGGYMTLMLLA 621
Query: 501 H-TNRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPWSNLEGYWEKSPLKYAPNVE 559
++ + V +++W G D Y ++ P N GY E L + +
Sbjct: 622 KASDSYACGVAGAPVTDW----GLYDSHY---TERYMDLPARNDAGYREARVLTHIEGLR 674
Query: 560 TPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDLSRSGRPKHRVKRLEL 619
+PLL+IH D + AL+ G+ EL +PG H LS HR + E
Sbjct: 675 SPLLLIHGMADDNVLFTNSTSLMSALQKRGQPFELMTYPGAKHGLS-GADALHRYRVAEA 733
Query: 620 IVG 622
+G
Sbjct: 734 FLG 736
>gi|6324793 dipeptidyl aminopeptidase; Ste13p [Saccharomyces cerevisiae]
>gi|461915|sp|P33894|DAP1_YEAST DIPEPTIDYL
AMINOPEPTIDASE A (DPAP A) (YSCIV) >gi|482577|pir||A49737
dipeptidyl aminopeptidase (EC 3.4.14.-) - yeast
(Saccharomyces cerevisiae) >gi|347197|gb|AAA35119.1|
(L21944) dipeptidyl aminopeptidase [Saccharomyces
cerevisiae] >gi|482810|gb|AAA17897.1| (U08230)
dipeptidyl aminopeptidase A [Saccharomyces cerevisiae]
>gi|1050771|emb|CAA63182.1| (X92441) YOR50-9
[Saccharomyces cerevisiae] >gi|1420508|emb|CAA99437.1|
(Z75127) ORF YOR219c [Saccharomyces cerevisiae]
Length = 931
Score = 88.9 bits (217), Expect = 2e-16
Identities = 74/256 (28%), Positives = 116/256 (44%), Gaps = 21/256 (8%)
Query: 361 FNAWIRDYKLSKPEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEIHGGP-----KTA 415
F I++Y L + + DG EI+ +KP + P +KYP ++ I+GGP T
Sbjct: 652 FKEKIKNYDLPITSYKTMVLDDGVEINYIEIKPANLNPKKKYPILVNIYGGPGSQTFTTK 711
Query: 416 YGYAFMHEFQVLVAKGFVVIFSNPRGSDGYGEEFAD-IRGHYGERDYQDLMEVVDEALKR 474
AF E V+ +V+ PRG+ G G F R G + +D+ EV + ++R
Sbjct: 712 SSLAF--EQAVVSGLDVIVLQIEPRGTGGKGWSFRSWAREKLGYWEPRDITEVTKKFIQR 769
Query: 475 -FDFIDEERLGVTGGSYGGFMTNWIVGHTN--RFKAAVTQRSISNWISFFGTTDIGYYFA 531
IDE ++ + G SYGGF + V N FK A+ ++NW + Y
Sbjct: 770 NSQHIDESKIAIWGWSYGGFTSLKTVELDNGDTFKYAMAVAPVTNWTLYDSVYTERYMNQ 829
Query: 532 PDQIGGDPWSNLEGYWEKSPLKYAPNVET--PLLIIHSTEDYRCWLPEALQFYIALKYLG 589
P + N EGY+E S ++ + E+ L I+H T D + + L LG
Sbjct: 830 PSE-------NHEGYFEVSTIQNFKSFESLKRLFIVHGTFDDNVHIQNTFRLVDQLNLLG 882
Query: 590 KT-VELAIFPGENHDL 604
T ++ IFP +H +
Sbjct: 883 LTNYDMHIFPDSDHSI 898
>pir||S75772 hypothetical protein slr0825 - Synechocystis sp. (strain PCC 6803)
>gi|1001263|dbj|BAA10507.1| (D64003) hypothetical
protein [Synechocystis sp.]
Length = 637
Score = 85.0 bits (207), Expect = 2e-15
Identities = 79/286 (27%), Positives = 124/286 (42%), Gaps = 17/286 (5%)
Query: 329 SVGDYIAFTAQDATTPTELYALR-DGKEKRI----TDFNAWIRDYKLSKPEHFRVTASDG 383
S G + F TT + + AL + +E I +DF + L++P+ + DG
Sbjct: 327 SDGKTLWFIGSGPTTSSAVVALAVEAQETEILKVASDFT--LDPAYLAQPQAISFSGDDG 384
Query: 384 KEIDAWIMKPV--DFK-PGRKYPAVL-EIHGGPKTAYGYAFMHEFQVLVAKGFVVIFSNP 439
+ AW P DF+ P P +L + HGGP A G + + Q ++GF + N
Sbjct: 385 QTAHAWYYPPTNGDFRGPSDALPPLLVKSHGGPTAAAGNSLSLKIQYWTSRGFAYVDVNY 444
Query: 440 RGSDGYGEEFAD-IRGHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWI 498
GS GYG ++ + G +G D D + L +D E+L ++GGS GG+ T
Sbjct: 445 GGSTGYGRDYRQRLNGQWGIVDVADCVNAA-RYLADQGLVDGEQLAISGGSAGGYTTLAA 503
Query: 499 VGHTNRFKAAVTQRSISNWISFFGTTDIGYYFAP--DQIGGDPWSNLEGYWEKSPLKYAP 556
+ N FKA + +S+ + TD + A D + G + Y +SP+ +A
Sbjct: 504 LTFHNVFKAGASYYGVSDLTAL--ATDTHKFEARYLDGLIGPYPERKDLYERRSPVNHAD 561
Query: 557 NVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENH 602
+ P++ ED + ALK G VE FP E H
Sbjct: 562 QLTCPVIFFQGLEDKVVPPNQTEMMVQALKAKGIKVEYVAFPEEQH 607
>pir||T33751 hypothetical protein R11E3.8 - Caenorhabditis elegans
>gi|3800993|gb|AAC68993.1| (AF100669) contains
similarity to prolyl oligopeptidase family (Pfam:
Prolyl_oligopep.hmm, score: 15.06) [Caenorhabditis
elegans]
Length = 745
Score = 84.3 bits (205), Expect = 4e-15
Identities = 68/257 (26%), Positives = 117/257 (45%), Gaps = 17/257 (6%)
Query: 382 DGKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAYGYAF-MHEFQVLVAKGFVVIFSNPR 440
DG + ++ P + G P V+ HGGP A ++ + L+ G+ V+ N R
Sbjct: 494 DGATYEGILIVPNE---GNNLPMVVNPHGGPHGASMASWPRRDLTTLLNSGYAVLQVNFR 550
Query: 441 GSDGYGEEFAD-IRGHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIV 499
GS G+G++F + G+ G+ D +D+ V L + I +++ + GGS+GGF+ + ++
Sbjct: 551 GSLGFGDDFIRALPGNCGDMDVKDVHNAVLTVLDKNPRISRDKVVLFGGSHGGFLVSHLI 610
Query: 500 G-HTNRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDP-WSNL------EGYWEKSP 551
G + +K+ V + N + TDI + + G P W+ + E + SP
Sbjct: 611 GQYPGFYKSCVALNPVVNIATMHDITDIPEWCYFEGTGEYPDWTKITTTEQREKMFNSSP 670
Query: 552 LKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDLSRSGRPK 611
+ + N TP L++ +D R +P F ALK G + +P NH L
Sbjct: 671 IAHVENATTPYLLLIGEKDLRV-VPHYRAFIRALKARGVPARVLTYPPSNHPLDEVNVEA 729
Query: 612 HRVKRLELIVGWFERWL 628
+ V WFE+ L
Sbjct: 730 DYAINM---VRWFEKSL 743
>gb|AAK41653.1| Acylaminoacyl-peptidase, putative (apeH-1) [Sulfolobus
solfataricus]
Length = 536
Score = 83.1 bits (202), Expect = 9e-15
Identities = 80/286 (27%), Positives = 134/286 (45%), Gaps = 36/286 (12%)
Query: 331 GDYIAFTAQDATTPTELYALRDGKE-KRITDFNAWIRDYK--LSKPEHFRVTASDGKEID 387
GDYI F +LY R GK+ +R+TD + D K KP +V + D +
Sbjct: 258 GDYIYFVNSKHDRSADLY--RYGKKVERLTDS---MNDAKGNFIKP---KVVSYDSNGLR 309
Query: 388 AWIMKPVDFKPGRKYPAVLEIHGGPKTAYGYAFMHEFQVLVAKGFVVIFSNPRGSDGYGE 447
+ + ++ G + ++ IHGGP +F E Q + +GF VI N RGS GYG
Sbjct: 310 IYALL---YEKGGEDKGIVYIHGGPDWECVNSFNPEIQFFMERGFKVICPNYRGSIGYGR 366
Query: 448 EFADIRGHYGERD--YQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVGHTNRF 505
F H ++D +L++V++ + +++ +TG SYGG++T + T +F
Sbjct: 367 RF----NHLNDKDPGGGELLDVINSV----KVLGVKKIAITGASYGGYLT---MMATTKF 415
Query: 506 K----AAVTQRSISNWISFFG-TTDIGYYFAPDQIGGDPWSNLEGYWEKSPLKYAPNVET 560
+AV NW + +I + ++G D NL ++SP+ + ++T
Sbjct: 416 SDLWCSAVAVVPFVNWFTEKKLEREILQLYDEIKVGND--ENL--LRDRSPIFFIDRIKT 471
Query: 561 PLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDLSR 606
LL++ D RC E LQ L+ LG+ V+ I+ E H ++
Sbjct: 472 SLLLLAGENDPRCPAEETLQVVEELRKLGREVKYKIYKDEGHGFAK 517
>pir||T15945 hypothetical protein F01F1.5 - Caenorhabditis elegans
>gi|529702|gb|AAC46639.1| (U13070) similar to
acylaminoacyl-peptidase [Caenorhabditis elegans]
Length = 629
Score = 80.0 bits (194), Expect = 8e-14
Identities = 63/236 (26%), Positives = 109/236 (45%), Gaps = 14/236 (5%)
Query: 369 KLSKPEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAYGYAFMHEFQVLV 428
++S+PE F V SDG ++ A + PV +L HGGP + Q
Sbjct: 366 EISEPEEF-VFKSDGVDVSAGTLPPV----------LLLGHGGPTAPAQNNLDLKKQFFT 414
Query: 429 AKGFVVIFSNPRGSDGYGEEFAD-IRGHYGERDYQDLMEVVDEALKRFDFIDEERLGVTG 487
++G V N RGS G+G EF + + G D D++ +AL +D E++ +TG
Sbjct: 415 SRGIAVFDVNYRGSTGFGTEFRRMLYKNCGVADRDDMLNGA-KALVEQGKVDAEKVLITG 473
Query: 488 GSYGGFMT-NWIVGHTNRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPWSNLEGY 546
S GG++ + ++ N KAAV+ +++ ++ T + + G Y
Sbjct: 474 SSSGGYLILSCLISPKNIIKAAVSVYGVADLLALDEDTHKLERCYNEMLIGKYPEQASIY 533
Query: 547 WEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENH 602
E+SP+ + + TP+ +H ED + +++ Y ++ G T L +F GE H
Sbjct: 534 EERSPIYHIDKIRTPIAFLHGREDTVVPMSQSITMYEKIRASGVTTALMLFDGEGH 589
>gb|AAG18962.1| (AE004997) Vng0409c [Halobacterium sp. NRC-1]
Length = 598
Score = 80.0 bits (194), Expect = 8e-14
Identities = 68/237 (28%), Positives = 103/237 (42%), Gaps = 7/237 (2%)
Query: 372 KPEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAYGYAFMHEFQVLVAKG 431
+PE R DG+EI A +P P +P +++ HGGP+ +F+ Q V G
Sbjct: 348 EPELVRYETFDGREIPALFTRPDGDGP---HPVIVDFHGGPEGQRRPSFLSLRQYFVDNG 404
Query: 432 FVVIFSNPRGSDGYGEEFADIRGHYGERD-YQDLMEVVDEALKRFDFIDEERLGVTGGSY 490
+ V N RGS GYG + ++ D D V+ R D ID +R+ GGSY
Sbjct: 405 YAVFEPNVRGSSGYGATYMNLDNVRNRMDAVADGKAGVEWLTARTD-IDADRVVAYGGSY 463
Query: 491 GGFMT-NWIVGHTNRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPWSNLEGYWEK 549
GGFM + + + A V I+N+++F T + G ++ E
Sbjct: 464 GGFMVLASLTEYPELWAAGVDIVGIANFVTFLENTGDWRREHRESEYGSLDADREFLESI 523
Query: 550 SPLKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDLSR 606
SP A + PLL++H D R + EA + + VE +F E H S+
Sbjct: 524 SPTNNADRIRAPLLVLHGANDPRVPVGEA-ERIVEQASAHVPVEKHVFDDEGHGFSK 579
>gb|AAG29769.1|AF221637_1 (AF221637) dipeptidyl peptidase 8 [Homo sapiens]
Length = 360
Score = 79.2 bits (192), Expect = 1e-13
Identities = 53/178 (29%), Positives = 90/178 (49%), Gaps = 13/178 (7%)
Query: 358 ITDFNAWIRDYKLSKPEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEIHGGPK---- 413
I D + DY + PE F ++ G + + KP D +PG+KYP VL I+GGP+
Sbjct: 188 ILDSAGPLPDY--TPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLV 245
Query: 414 -TAYGYAFMHEFQVLVAKGFVVIFSNPRGSDGYGEEF-ADIRGHYGERDYQDLMEVVDEA 471
+ L + G+VV+ + RGS G +F + G+ + D +E +
Sbjct: 246 NNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYL 305
Query: 472 LKRFDFIDEERLGVTGGSYGGFMTNW-IVGHTNRFKAAVTQRSISNWISFFGTTDIGY 528
R+DFID +R+G+ G SYGG+++ ++ ++ F+ A+ ++ WI + D GY
Sbjct: 306 ASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFY----DTGY 359
>emb|CAB39035.2| (AL034559) putative acylaminoacyl-peptidase [Plasmodium falciparum]
Length = 1074
Score = 77.6 bits (188), Expect = 4e-13
Identities = 58/210 (27%), Positives = 98/210 (46%), Gaps = 14/210 (6%)
Query: 405 VLEIHGGPKTAYGYAFMHEFQVLVAKGFVVIFSNPRGSDGYGEEFADIRGHYGERDYQDL 464
+L IHGGP + + + F A GF V+ N GS + + + GH + D+
Sbjct: 843 ILYIHGGPYSIILNEYKNIFIFFAASGFDVLCVNYIGSLTFSNKLNILSGHINSIEIDDI 902
Query: 465 MEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVGHTNR-FKAAVTQRSISNWISFFGT 523
+ + + + F D E + + GGSYG F + ++ N FK+A + WI +
Sbjct: 903 INIFKDFVNYFG--DYENIYLYGGSYGAFASCALLTKYNSLFKSACIINGVYEWILSTYS 960
Query: 524 TDIGYYFAPDQIGGDPWSNL------EGY---WEKSPLKYAPNVETPLLIIHSTEDYRCW 574
+D+ +F I + +S E Y ++ SP+ YA N+ +P+LII S +D R
Sbjct: 961 SDVPDFFL--NITRNKFSEYDYNLSKEDYTLLYDMSPINYAHNISSPILIICSKDDKRVS 1018
Query: 575 LPEALQFYIALKYLGKTVELAIFPGENHDL 604
++ Y L+ L K +L +F NH +
Sbjct: 1019 YHNSIALYNKLRALKKKCKLFLFQNTNHSI 1048
>sp|P34422|YL31_CAEEL HYPOTHETICAL 86.0 KDA PROTEIN F44B9.1 IN CHROMOSOME III
>gi|630620|pir||S44807 F44B9.1 protein - Caenorhabditis
elegans >gi|388586|gb|AAA28026.1| (L23648) homology with
acylamino-acid-releasing enzyme; putative
[Caenorhabditis elegans]
Length = 761
Score = 77.3 bits (187), Expect = 5e-13
Identities = 74/301 (24%), Positives = 124/301 (40%), Gaps = 29/301 (9%)
Query: 334 IAFTAQDATTPTELYALRDGKEKRITDFNAWIRDYKLSKPEHFRVTASDGKEIDAWIMKP 393
+ +++ D LY + K + ++ Y L+K F A D I A++ P
Sbjct: 362 VTYSSSDEPYDIYLYRRWNKKAELFMSTRPELKKYTLNKQIGFDFRARDEMTIQAYLSLP 421
Query: 394 --------------------VDFKPGRKYPAVLEIHGGPKTAYGYAFMHEFQVLVAKGFV 433
+ P ++ +HGGPK Y F L +G+
Sbjct: 422 PQAPLLKSSQVPDGDRPYANLGMIPAVPQKMIVLVHGGPKARDHYGFSPMNAWLTNRGYS 481
Query: 434 VIFSNPRGSDGYGEEFADI-RGHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGG 492
V+ N RGS G+G+ + G +G + + D+++ V+ A+ + + + V GGSYGG
Sbjct: 482 VLQVNFRGSTGFGKRLTNAGNGEWGRKMHFDILDAVEFAVSK-GIANRSEVAVMGGSYGG 540
Query: 493 FMTNWIVGHTNR-FKAAVTQRSISNWISFFGTTD---IGYYFAPDQIGGDPWSNLEG--- 545
+ T + T + F V SN IS +G+ ++ G S+ EG
Sbjct: 541 YETLVALTFTPQTFACGVDIVGPSNLISLVQAIPPYWLGFRKDLIKMVGADISDEEGRQS 600
Query: 546 YWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDLS 605
+SPL +A V P++II D R E+ QF AL+ V ++P E H +
Sbjct: 601 LQSRSPLFFADRVTKPIMIIQGANDPRVKQAESDQFVAALEKKHIPVTYLLYPDEGHGVR 660
Query: 606 R 606
+
Sbjct: 661 K 661
>gb|AAF52407.2| (AE003614) CG11319 gene product [Drosophila melanogaster]
Length = 988
Score = 77.3 bits (187), Expect = 5e-13
Identities = 56/219 (25%), Positives = 97/219 (43%), Gaps = 11/219 (5%)
Query: 401 KYPAVLEIHGGPKTAYGYAFMH---EFQVLVAKGFVVIFSNPRGSDGYGEEFA-DIRGHY 456
+YP +L ++ GP + H + +K ++V+ + RGS G G + ++
Sbjct: 739 RYPTILHVYSGPGSQLVTDHWHVDWNTYLSGSKDYIVVEIDGRGSAGQGYQLLHEVYKRL 798
Query: 457 GERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNW-IVGHTNRFKAAVTQRSIS 515
G + D +EV + FID R+GV G SYGG+ + G + F+ ++ ++
Sbjct: 799 GSVEVSDQLEVSEYLRDNLHFIDSRRMGVWGWSYGGYTAALALAGQQSIFQCGISVSPVT 858
Query: 516 NWISFFGTTDIGYYFAPDQIGGDPWSNLEGYWEKSPLKYAPNV-ETPLLIIHSTEDYRCW 574
NW + T Y P+ N +GY E KY N+ + L++H T D
Sbjct: 859 NWKLYDSTYAERYLSFPNVT-----DNYKGYEESDLSKYVDNLRDRQFLLVHGTADDNVH 913
Query: 575 LPEALQFYIALKYLGKTVELAIFPGENHDLSRSGRPKHR 613
+ +++ +L G + I+P E H LS R +R
Sbjct: 914 VQQSMVLARSLTSKGVLYKQQIYPDEGHSLSGVKRHLYR 952
>pir||T32919 hypothetical protein K02F2.1 - Caenorhabditis elegans
>gi|2804453|gb|AAB97564.1| (AF043699) contains
similarity to the prolyl oligopeptidase family
[Caenorhabditis elegans]
Length = 931
Score = 75.3 bits (182), Expect = 2e-12
Identities = 65/227 (28%), Positives = 100/227 (43%), Gaps = 24/227 (10%)
Query: 388 AWIMKPVDFKPGRKYPAVLEIHGGPKTAYGYAFMH------EFQVLVAKGFVVIFSNPRG 441
A I++P +F P +KYP ++GGP G +H ++ G+VV+F + RG
Sbjct: 679 AMILRPSNFDPYKKYPVFHYVYGGP----GIQIVHNDFSWIQYIRFCRLGYVVVFIDNRG 734
Query: 442 SDGYGEEF-ADIRGHYGERDYQDLMEVVDEALKRF-DFIDEERLGVTGGSYGGFMT-NWI 498
S G EF I G + +D +E + +R F+D R+ V G SYGG+M I
Sbjct: 735 SAHRGIEFERHIHKKMGTVEVEDQVEGLQMLAERTGGFMDMSRVVVHGWSYGGYMALQMI 794
Query: 499 VGHTNRFKAAVTQRSISNWISF---FGTTDIGYYFAPDQIGGDPWSNLEGYWEKSPLKYA 555
H N ++AA+ ++S+W + + +GY G S++ G EK
Sbjct: 795 AKHPNIYRAAIAGGAVSDWRLYDTAYTERYMGYPLEEHVYGA---SSITGLVEK-----L 846
Query: 556 PNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENH 602
P+ L+++H D GK EL IFP E H
Sbjct: 847 PDEPNRLMLVHGLMDENVHFAHLTHLVDECIKKGKWHELVIFPNERH 893
>pir||T19514 hypothetical protein C27C12.7 - Caenorhabditis elegans
>gi|3892135|emb|CAA93743.1| (Z69883) Similarity to Yeast
dipeptidyl aminopeptidase (SW:DAP1_YEAST), contains
similarity to Pfam domain: PF00326 (Prolyl
oligopeptidase family), Score=39.9, E-value=1.5e-11,
N=1; PF00930 (Dipeptidyl peptidase IV (DPP IV)
N-terminal region), Score=77>
Length = 829
Score = 75.3 bits (182), Expect = 2e-12
Identities = 58/225 (25%), Positives = 101/225 (44%), Gaps = 18/225 (8%)
Query: 390 IMKPVDFKPGRKYPAVLEIHGGPKTAYGYA---FMHEFQVLVAKGFVVIFSNPRGSDGYG 446
++ P + G K P +L+I+GGP + + H Q++ + RG+ G G
Sbjct: 588 MLTPANLLDGAKIPLLLDIYGGPDSKQVFQKTPTAHAIQIVSQYDIAYARIDVRGTGGRG 647
Query: 447 EEFAD-IRGHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVGHTNRF 505
+ + + G+ + D ++++ + F FIDE+R+ V G SYGGF+T+
Sbjct: 648 WDVKEAVYRKLGDAEVVDTLDMIRAFINTFGFIDEDRIAVMGWSYGGFLTS--------- 698
Query: 506 KAAVTQRS--ISNWISFFGTTDIGYYFA--PDQIGGDPWSNLEGYWEKSPLKYAPNV-ET 560
K A+ + + IS TD YY + ++ G P NL+GY + + +A NV
Sbjct: 699 KIAIKDQGELVKCAISIAPVTDFKYYDSAYTERYLGQPAENLQGYINTNVIPHARNVTNV 758
Query: 561 PLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDLS 605
L+ H D + ++ AL+ G ++ E H LS
Sbjct: 759 KYLLAHGERDDNVHYQNSARWSEALQQNGIHFTQLVYANEAHSLS 803
>gb|AAC33801.1| (AC005594) R26984_1 [Homo sapiens]
Length = 508
Score = 74.9 bits (181), Expect = 3e-12
Identities = 69/261 (26%), Positives = 116/261 (44%), Gaps = 30/261 (11%)
Query: 364 WIRDYKLSKPEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAY------G 417
W + +K HF T SD + + I KP +PG+K+P VL ++GGP+ G
Sbjct: 237 WASMMEAAKIFHFH-TRSDVR-LYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKG 294
Query: 418 YAFMHEFQVLVAKGFVVIFSNPRGSDGYGEEFAD-IRGHYGERDYQDLMEVVDEALKRFD 476
++ L + G+ V+ + RGS G F ++ G+ + +D +E + +++
Sbjct: 295 IKYLR-LNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYG 353
Query: 477 FIDEERLGVTGGSYGGFMTNWIVGHTNR-FKAAVTQRSISNWISFFGTTDIGYYFAPDQI 535
FID R+ + G SYGGF++ + H + FK A+ ++ W+++ D GY ++
Sbjct: 354 FIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAY----DTGY---TERY 406
Query: 536 GGDPWSNLEGYWEKS---PLKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTV 592
P +N GY S ++ PN LLI+H D L GK
Sbjct: 407 MDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPY 466
Query: 593 EL---------AIFPGENHDL 604
+L I+P E H +
Sbjct: 467 QLQVALPPVSPQIYPNERHSI 487
>pir||D72636 probable acylamino-acid-releasing enzyme APE1547 - Aeropyrum pernix
(strain K1) >gi|5105232|dbj|BAA80546.1| (AP000061) 582aa
long hypothetical acylamino-acid-releasing enzyme
[Aeropyrum pernix]
Length = 582
Score = 74.1 bits (179), Expect = 4e-12
Identities = 67/231 (29%), Positives = 103/231 (44%), Gaps = 12/231 (5%)
Query: 378 VTASDGKEIDAWIMKPVDFK-PGRKYPAVLEIHGGPKTAYGYAFMHEFQVLVAKGFVVIF 436
V + DG + ++++ PG P V+ +HGGP ++ L A GF V+
Sbjct: 338 VESFDGSRVPTYVLESGRAPTPG---PTVVLVHGGPFAEDSDSWDTFAASLAAAGFHVVM 394
Query: 437 SNPRGSDGYGEEFA-DIRGHYGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMT 495
N RGS GYGEE+ I G + +D+ A R + E L + G SYGG+MT
Sbjct: 395 PNYRGSTGYGEEWRLKIIGDPCGGELEDVSAAARWA--RESGLASE-LYIMGYSYGGYMT 451
Query: 496 NW-IVGHTNRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPWSNLEGYWEKSPLKY 554
+ FKA V S+ +W + +D + +Q+ G + E +SP+ +
Sbjct: 452 LCALTMKPGLFKAGVAGASVVDWEEMYELSDAAFRNFIEQLTG---GSREIMRSRSPINH 508
Query: 555 APNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDLS 605
++ PL +IH D R L L+ L GKT E I P H ++
Sbjct: 509 VDRIKEPLALIHPQNDSRTPLKPLLRLMGELLARGKTFEAHIIPDAGHAIN 559
>pir||G82543 conserved hypothetical protein XF2551 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9107762|gb|AAF85348.1|AE004062_3 (AE004062)
conserved hypothetical protein [Xylella fastidiosa]
Length = 891
Score = 74.1 bits (179), Expect = 4e-12
Identities = 72/296 (24%), Positives = 130/296 (43%), Gaps = 33/296 (11%)
Query: 348 YALRDGKEKRITDFNAWIRDYKLSKPEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLE 407
YA + ITD +R K + R +DG ++ + P D++ G++ PA+L
Sbjct: 600 YASSTARITHITDPTPEVRQIKKRLVTYKR---NDGVDLSFTLYTPPDYQEGQRLPAILY 656
Query: 408 IH---------GGPKTAYGYAF--MHEFQVLVAKGFVVIFSNPRGSDGYGEEFADIRGHY 456
+ G T + F + +++L+ G+ +I + G + D Y
Sbjct: 657 AYPTDFANSTQAGQVTGSQHTFTRLPYYRLLLLAGYAIIDNASFPIVGDPKTAYDT---Y 713
Query: 457 GERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVGHTNRFKAAV-TQRSIS 515
E+ D VD+A+ +D ER+G+TG S+G MT ++ HT+ F+A V + S +
Sbjct: 714 LEQLKADATAAVDKAVA-LGVVDRERIGITGHSHGALMTANLIAHTDLFRAGVASSGSYN 772
Query: 516 NWISFFGTTDIGYYFAPDQIGGDPWSNLEGYWEKSPLKYAPNVETPLLIIHSTEDYRCWL 575
+ FG + W + Y + SP YA ++ PLL+IH +D
Sbjct: 773 KTFTPFGFQNERRIL---------WQAKDVYLKASPFFYADKIKHPLLLIHGEDDANPGT 823
Query: 576 P--EALQFYIALKYLGKTVELAIFPGENHDLSRSGRPKHRVKRLELIVGWFERWLK 629
++ +FY A++ G +L + P E H + + V + + WF+ ++K
Sbjct: 824 EPFQSRKFYQAIRGNGGIAKLVMLPHEPHWYAALESNEQFVYEM---LNWFDTYVK 876
>pir||F82858 dipeptidyl-peptidase XF0015 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9104777|gb|AAF82828.1|AE003856_7
(AE003856) dipeptidyl-peptidase [Xylella fastidiosa]
Length = 795
Score = 73.7 bits (178), Expect = 6e-12
Identities = 68/270 (25%), Positives = 117/270 (43%), Gaps = 24/270 (8%)
Query: 372 KPEHFRVTASDGKEIDAW--IMKPVDFKPGRKYPAVLEIHGGP-----KTAYGYAFMHEF 424
+PE+ ++ + G + W P +P ++YP V+ +HG Y F +
Sbjct: 537 QPEYVQIPSKHGAGV-IWGKYYGPASLQPEKRYPIVMFVHGAGYLQNVSARYPSYFREQM 595
Query: 425 --QVLVAKGFVVIFSNPRGSDGYGEEFAD-IRGHYGERDYQDLMEVVDEALKRFDFIDEE 481
+LV KG++V+ + R S G+G ++ I + G + +D ++ +D + D
Sbjct: 596 FHTLLVQKGYIVLDLDYRASAGHGRDWRTAIYRNMGHPELEDYLDGLDWLVAHKQG-DRR 654
Query: 482 RLGVTGGSYGGFMTNWIVGHT-NRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPW 540
R G+ GGSYGGFMT + FKA R + +W+ + + I P
Sbjct: 655 RAGMYGGSYGGFMTYMAMFRAPGTFKAGAALRPVGDWMQY-------NHEYTSNILNTPE 707
Query: 541 SNLEGYWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGK-TVELAIFPG 599
+ + Y S + YA ++ LLI+H D + +++ L L K E+ +P
Sbjct: 708 LDPDAYQRSSAINYAEALQGHLLILHGMIDDNVFFKDSVDMVQKLIELRKDNWEIVPYPL 767
Query: 600 ENHDLSRSGRPKHRVKRLELIVGWFERWLK 629
E H + P V + I+ FE LK
Sbjct: 768 ERHSFT---HPDAWVDEYKRILKLFETQLK 794
>pir||A39914 dipeptidyl-peptidase IV (EC 3.4.14.5), membrane-bound form
precursor - rat >gi|204464|gb|AAA41272.1| (J02997) bile
canaliculus-specific membrane glycoprotein precursor
[Rattus norvegicus]
Length = 792
Score = 72.6 bits (175), Expect = 1e-11
Identities = 67/279 (24%), Positives = 121/279 (43%), Gaps = 23/279 (8%)
Query: 347 LYALRDGKEKRITDFNA----WIRDYKL-SKPEHFRVTASDGKEIDAW--IMKPVDFKPG 399
L+ D KE R+ + N+ ++D ++ SK F V E W ++ P F
Sbjct: 483 LHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDFIVL----NETRFWYQMILPPHFDKS 538
Query: 400 RKYPAVLEIHGGP---KTAYGYAFMHEFQVLVAKGFVVIFSNPRGSDGYGEEFAD-IRGH 455
+KYP +++++ GP K + F + + +V + RGS G++ I
Sbjct: 539 KKYPLLIDVYAGPCSQKADAAFRFNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKR 598
Query: 456 YGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVGH-TNRFKAAVTQRSI 514
G + +D +E + LK F+D +++ + G SYGG++T+ ++G + FK + +
Sbjct: 599 LGTLEVEDQIEAARQFLK-MGFVDSKQVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPV 657
Query: 515 SNWISFFGTTDIGYYFAPDQIGGDPWSNLEGYWEKSPLKYAPNV-ETPLLIIHSTEDYRC 573
S W + Y P P NL+ Y + + A N + L+IH T D
Sbjct: 658 SRWEYYDSVYTERYMGLP-----TPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNV 712
Query: 574 WLPEALQFYIALKYLGKTVELAIFPGENHDLSRSGRPKH 612
++ Q AL G + + E+H ++ S +H
Sbjct: 713 HFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQH 751
>pir||F83397 probable peptidase PA1990 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9947991|gb|AAG05378.1|AE004625_8
(AE004625) probable peptidase [Pseudomonas aeruginosa]
Length = 608
Score = 72.2 bits (174), Expect = 2e-11
Identities = 63/252 (25%), Positives = 106/252 (42%), Gaps = 14/252 (5%)
Query: 370 LSKPEHFRVTASDGKEIDAWIMKPVDFK----PGRKYPAVLEIHGGPKTAYGYAFMHEFQ 425
LS P+ F +G+ + P + + P R P ++ +HGGP + + AF Q
Sbjct: 347 LSHPQAFVYGLGNGENGHGFFYPPRNARRRVDPRRPPPLLVWLHGGPTSMHSPAFDAGLQ 406
Query: 426 VLVAKGFVVIFSNPRGSDGYGEEFAD-IRGHYGERDYQDLMEVVDEALKRFD---FIDEE 481
+GF V N RGS GYG + +RG +G + +D ++ AL + D +ID
Sbjct: 407 FWTQRGFAVAALNYRGSSGYGRAYRQRLRGQWGRLELRD----IEAALAQLDAEGWIDRA 462
Query: 482 RLGVTGGSYGGFMTNWIVGHTNRFKAAVTQRSISNWISFFGTTDIGYYFAPDQIGGDPWS 541
R+ V G S GG+ + + + + +S+ ++ T D + GDP
Sbjct: 463 RVFVRGASAGGYSALRALACLDGLRGGASLYGVSDPLALARCTHKFEGDYLDWLIGDPQR 522
Query: 542 NLEGYWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQFYIA-LKYLGKTVELAIFPGE 600
Y +SP+ + P++ D +PE + +A L+ G VE +P E
Sbjct: 523 QRRRYLVRSPVLQVGRIRAPVVFFQGGLD-AVVVPEQTEAMVAGLRRSGVRVECHRYPQE 581
Query: 601 NHDLSRSGRPKH 612
H + H
Sbjct: 582 RHGFRQPANRAH 593
>gi|6978773 dipeptidyl peptidase 4 [Rattus norvegicus]
>gi|118905|sp|P14740|DPP4_RAT DIPEPTIDYL PEPTIDASE IV
(DPP IV) (GP110 GLYCOPROTEIN) (BILE CANALICULUS
DOMAIN-SPECIFIC MEMBRANE GLYCOPROTEIN)
>gi|203974|gb|AAA41096.1| (J04591) dipeptidyl peptidase
IV (EC 3.4.14.5) [Rattus norvegicus]
Length = 767
Score = 71.8 bits (173), Expect = 2e-11
Identities = 67/279 (24%), Positives = 120/279 (42%), Gaps = 23/279 (8%)
Query: 347 LYALRDGKEKRITDFNA----WIRDYKL-SKPEHFRVTASDGKEIDAW--IMKPVDFKPG 399
L+ D KE R+ + N+ ++D ++ SK F V E W ++ P F
Sbjct: 483 LHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDFIVL----NETRFWYQMILPPHFDKS 538
Query: 400 RKYPAVLEIHGGP---KTAYGYAFMHEFQVLVAKGFVVIFSNPRGSDGYGEEFAD-IRGH 455
+KYP +++++ GP K + + + +V + RGS G++ I
Sbjct: 539 KKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKR 598
Query: 456 YGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVGH-TNRFKAAVTQRSI 514
G + +D +E + LK F+D +R+ + G SYGG++T+ ++G + FK + +
Sbjct: 599 LGTLEVEDQIEAARQFLK-MGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPV 657
Query: 515 SNWISFFGTTDIGYYFAPDQIGGDPWSNLEGYWEKSPLKYAPNV-ETPLLIIHSTEDYRC 573
S W + Y P P NL+ Y + + A N + L+IH T D
Sbjct: 658 SRWEYYDSVYTERYMGLP-----TPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNV 712
Query: 574 WLPEALQFYIALKYLGKTVELAIFPGENHDLSRSGRPKH 612
++ Q AL G + + E+H ++ S +H
Sbjct: 713 HFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQH 751
>pir||T35378 probable peptide hydrolase - Streptomyces coelicolor
>gi|5123885|emb|CAB45477.1| (AL079348) putative peptide
hydrolase [Streptomyces coelicolor A3(2)]
Length = 606
Score = 71.4 bits (172), Expect = 3e-11
Identities = 68/241 (28%), Positives = 105/241 (43%), Gaps = 10/241 (4%)
Query: 383 GKEIDAWIMKPVDFKPGRKYPAVLEIHGGPKTAYGYAFMHEFQVLVAKGFVVIFSNPRGS 442
G I A + KP P V +IHGGP +F V G+ V+ N RGS
Sbjct: 362 GGRIHALVQKPAG--AAGPLPTVFDIHGGPTWHDSDSFAAGPAAWVDHGYAVVRVNYRGS 419
Query: 443 DGYGEEFADIRGH-YGERDYQDLMEVVDEALKRFDFIDEERLGVTGGSYGGFMTNWIVG- 500
GYG + D H G + +D+ V + A+ D ERL +TGGS+GG++T +G
Sbjct: 420 TGYGRAWTDALKHRVGLIELEDIAAVREWAVAS-GLADPERLILTGGSWGGYLTLLGIGT 478
Query: 501 HTNRFKAAVTQRSISNWISFFGTTDIGYYFAPDQ--IGGDPWSNLEGYWEKSPLKYAPNV 558
+ + ++++++ + G A D+ +GG P E + SPL Y V
Sbjct: 479 QPEAWTLGIAAVPVADYVTAYHDEMEGLK-ALDRTLLGGTPEEVPERFEASSPLTYVDEV 537
Query: 559 ETPLLIIHSTEDYRCWLPEALQFYIALKYLGKTVELAIFPGENHDLSRSGRPKHRVKRLE 618
+ P+ I D RC + + + L+ G E+ + + L R K RLE
Sbjct: 538 KAPVYISAGVNDPRCPIRQVENYVERLEARGAVHEVYRYDAGHGSLVVDERIKQ--VRLE 595
Query: 619 L 619
L
Sbjct: 596 L 596
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.320 0.141 0.425
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 254878757
Number of Sequences: 2977
Number of extensions: 11681306
Number of successful extensions: 23041
Number of sequences better than 1.0e-10: 56
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 22822
Number of HSP's gapped (non-prelim): 92
length of query: 631
length of database: 189,106,746
effective HSP length: 54
effective length of query: 577
effective length of database: 156,788,448
effective search space: 90466934496
effective search space used: 90466934496
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 168 (69.9 bits)