BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1307 (mutS-like) DE:DNA MISMATCH RECOGNITION PROTEIN MUTS.
(570 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||A75007 DNA mismatch recognition protein muts. PAB1307 - Pyr... 1104 0.0
pir||C71155 hypothetical protein PH0442 - Pyrococcus horikoshii ... 859 0.0
pir||C69102 DNA mismatch recognition protein MutS - Methanobacte... 207 2e-52
gb|AAG20386.1| (AE005111) mismatch repair protein; MutS3 [Haloba... 174 2e-42
>pir||A75007 DNA mismatch recognition protein muts. PAB1307 - Pyrococcus abyssi
(strain Orsay) >gi|5459009|emb|CAB50495.1| (AJ248288)
DNA MISMATCH RECOGNITION PROTEIN MUTS. [Pyrococcus
abyssi]
Length = 570
Score = 1104 bits (2825), Expect = 0.0
Identities = 570/570 (100%), Positives = 570/570 (100%)
Query: 1 MKLKLRGDAREIYRAIRRKIESEIRVSEAKRFLDNFEPVSDVGEILKRQNYLKRAMESVS 60
MKLKLRGDAREIYRAIRRKIESEIRVSEAKRFLDNFEPVSDVGEILKRQNYLKRAMESVS
Sbjct: 1 MKLKLRGDAREIYRAIRRKIESEIRVSEAKRFLDNFEPVSDVGEILKRQNYLKRAMESVS 60
Query: 61 EEVEGLLLKVKPIKFRKEFLGDRLLVVSEDEVEEAEKLGLCMVSTEPIEGYDIVLSTIGY 120
EEVEGLLLKVKPIKFRKEFLGDRLLVVSEDEVEEAEKLGLCMVSTEPIEGYDIVLSTIGY
Sbjct: 61 EEVEGLLLKVKPIKFRKEFLGDRLLVVSEDEVEEAEKLGLCMVSTEPIEGYDIVLSTIGY 120
Query: 121 GIDVELKPYEIAPELYIKPLWESRDVLEALARIFPGGAAAKILRELEGIEDVMRRNERLE 180
GIDVELKPYEIAPELYIKPLWESRDVLEALARIFPGGAAAKILRELEGIEDVMRRNERLE
Sbjct: 121 GIDVELKPYEIAPELYIKPLWESRDVLEALARIFPGGAAAKILRELEGIEDVMRRNERLE 180
Query: 181 NIEEIIRRYESELNKRIEEKLERFKLTLSGKELVEFLRSLRYGDVEAILSKFSSLNDDII 240
NIEEIIRRYESELNKRIEEKLERFKLTLSGKELVEFLRSLRYGDVEAILSKFSSLNDDII
Sbjct: 181 NIEEIIRRYESELNKRIEEKLERFKLTLSGKELVEFLRSLRYGDVEAILSKFSSLNDDII 240
Query: 241 EEIRKAEEKLSQELGVAIEVFPRDYPVEVPPDVVERLKRSVERELKIELYMRAREIVPRI 300
EEIRKAEEKLSQELGVAIEVFPRDYPVEVPPDVVERLKRSVERELKIELYMRAREIVPRI
Sbjct: 241 EEIRKAEEKLSQELGVAIEVFPRDYPVEVPPDVVERLKRSVERELKIELYMRAREIVPRI 300
Query: 301 IPYIQGLKEEIERAYELEFILALKRFSRGFTFPKIEEGGIGFIKGRNLFIENPQPVSYFV 360
IPYIQGLKEEIERAYELEFILALKRFSRGFTFPKIEEGGIGFIKGRNLFIENPQPVSYFV
Sbjct: 301 IPYIQGLKEEIERAYELEFILALKRFSRGFTFPKIEEGGIGFIKGRNLFIENPQPVSYFV 360
Query: 361 GSAKGQFKGIQESSVVILTGANSGGKTSLLELMLQIVILAHMGLPVPASEAWVEPLDEVF 420
GSAKGQFKGIQESSVVILTGANSGGKTSLLELMLQIVILAHMGLPVPASEAWVEPLDEVF
Sbjct: 361 GSAKGQFKGIQESSVVILTGANSGGKTSLLELMLQIVILAHMGLPVPASEAWVEPLDEVF 420
Query: 421 FFKRKRINYGAGAFESSLKSIVKALKGKGRKLILIDEFEAITEPGAAAKILAELLKIGVE 480
FFKRKRINYGAGAFESSLKSIVKALKGKGRKLILIDEFEAITEPGAAAKILAELLKIGVE
Sbjct: 421 FFKRKRINYGAGAFESSLKSIVKALKGKGRKLILIDEFEAITEPGAAAKILAELLKIGVE 480
Query: 481 KGFYIVIVSHLGEDLKKELPYARVDGIEASGLDEELNLIVDRQPKFGVIGKSTPELILER 540
KGFYIVIVSHLGEDLKKELPYARVDGIEASGLDEELNLIVDRQPKFGVIGKSTPELILER
Sbjct: 481 KGFYIVIVSHLGEDLKKELPYARVDGIEASGLDEELNLIVDRQPKFGVIGKSTPELILER 540
Query: 541 LARKGRGEEREILMKVLAKLNNTYVPTQNI 570
LARKGRGEEREILMKVLAKLNNTYVPTQNI
Sbjct: 541 LARKGRGEEREILMKVLAKLNNTYVPTQNI 570
>pir||C71155 hypothetical protein PH0442 - Pyrococcus horikoshii
>gi|3256845|dbj|BAA29528.1| (AP000002) 560aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 560
Score = 859 bits (2194), Expect = 0.0
Identities = 420/558 (75%), Positives = 495/558 (88%)
Query: 3 LKLRGDAREIYRAIRRKIESEIRVSEAKRFLDNFEPVSDVGEILKRQNYLKRAMESVSEE 62
+KLRGDAR++Y+ IR IE EI++ EAK+FLD EP SD EIL+RQ Y K++ SV EE
Sbjct: 1 MKLRGDARDVYKRIRGMIEREIKLEEAKKFLDRIEPTSDKLEILRRQEYFKKSFSSVKEE 60
Query: 63 VEGLLLKVKPIKFRKEFLGDRLLVVSEDEVEEAEKLGLCMVSTEPIEGYDIVLSTIGYGI 122
+E LLKVKPIKFR+EFL DR+L+VSEDEVEEAEKL LC+VSTEPIEGYDIVLSTIGYGI
Sbjct: 61 LEDFLLKVKPIKFRREFLDDRVLIVSEDEVEEAEKLNLCIVSTEPIEGYDIVLSTIGYGI 120
Query: 123 DVELKPYEIAPELYIKPLWESRDVLEALARIFPGGAAAKILRELEGIEDVMRRNERLENI 182
+VELKPYEIAPELY+KPLWE+R VLEALA +FP G + KIL L +EDV +R + LEN+
Sbjct: 121 EVELKPYEIAPELYVKPLWENRGVLEALANVFPNGVSRKILERLNELEDVFKRLKTLENL 180
Query: 183 EEIIRRYESELNKRIEEKLERFKLTLSGKELVEFLRSLRYGDVEAILSKFSSLNDDIIEE 242
EE IR E ELN++IEEKLE FKLTLSG+ELVEF+R+LR GD+E +LSKFS+LND+I++E
Sbjct: 181 EERIRELEIELNRKIEEKLEDFKLTLSGRELVEFIRALRSGDIEVVLSKFSALNDEILDE 240
Query: 243 IRKAEEKLSQELGVAIEVFPRDYPVEVPPDVVERLKRSVERELKIELYMRAREIVPRIIP 302
I+K EE+LS+ELG+ +EVFPRDYP+EVPP+VVE L++SVERELK+ELY+++RE++ I+P
Sbjct: 241 IKKTEEELSKELGIDVEVFPRDYPIEVPPEVVESLRKSVERELKLELYLKSREVLEDILP 300
Query: 303 YIQGLKEEIERAYELEFILALKRFSRGFTFPKIEEGGIGFIKGRNLFIENPQPVSYFVGS 362
Y+ LKEEIE+AYELEFI+ALKRFS+GFTFPKIEEGGIGF+KG+NLFIENPQPVSYFVG
Sbjct: 301 YLPKLKEEIEKAYELEFIIALKRFSKGFTFPKIEEGGIGFVKGKNLFIENPQPVSYFVGK 360
Query: 363 AKGQFKGIQESSVVILTGANSGGKTSLLELMLQIVILAHMGLPVPASEAWVEPLDEVFFF 422
A+ F G++ S VVILTGANSGGKTSLLELMLQIV+LAHMGLPVPA AWV+ L+EVFFF
Sbjct: 361 AREPFAGVKGSRVVILTGANSGGKTSLLELMLQIVVLAHMGLPVPAENAWVDVLNEVFFF 420
Query: 423 KRKRINYGAGAFESSLKSIVKALKGKGRKLILIDEFEAITEPGAAAKILAELLKIGVEKG 482
K+KR +YGAGAFE SLK IV++L+GKG+KLILIDEFEAITEPGAA KILAELLK+G+ KG
Sbjct: 421 KKKRSSYGAGAFEGSLKGIVRSLRGKGKKLILIDEFEAITEPGAAVKILAELLKVGISKG 480
Query: 483 FYIVIVSHLGEDLKKELPYARVDGIEASGLDEELNLIVDRQPKFGVIGKSTPELILERLA 542
FYIVIVSHLGEDL KELP ARVDGIEASGLDE LNLIVDRQPKFG+IG+STPELILERLA
Sbjct: 481 FYIVIVSHLGEDLMKELPEARVDGIEASGLDENLNLIVDRQPKFGIIGRSTPELILERLA 540
Query: 543 RKGRGEEREILMKVLAKL 560
RKGRGEER+IL+KVL KL
Sbjct: 541 RKGRGEERDILLKVLRKL 558
>pir||C69102 DNA mismatch recognition protein MutS - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622891|gb|AAB86228.1| (AE000931) DNA mismatch
recognition protein MutS [Methanobacterium
thermoautotrophicum]
Length = 647
Score = 207 bits (522), Expect = 2e-52
Identities = 170/591 (28%), Positives = 286/591 (47%), Gaps = 65/591 (10%)
Query: 9 AREIYRAIRRKIESEIRVSEAKRFLDNFEPVSDVGEILKRQNYLKRAMESVSE----EVE 64
A +IYR I + S A+ + P +D + + + A + V E ++
Sbjct: 80 AFQIYRDILELMMSYAHTDYARNRIMLLHPTTDTASMREHIRMVMEAKKMVEELPVEKLR 139
Query: 65 GLLLKVK-----PIKFRKEFLGDRLLVVSEDEVEEAEKLGL-----CMVSTEP--IEGYD 112
GLL + PI F +LV + ++ + +GL +++ +P ++ Y+
Sbjct: 140 GLLSNIDRPRDPPINFNPS---KAILVETREDYDLLIDMGLNRYHPVILNPDPGELDEYE 196
Query: 113 IVLSTIGYG------------IDVELKPYEIAPELYI----KPLWESRDVLEALARIFPG 156
+++ G + + +EI PE + K L R+ LE + RI
Sbjct: 197 LIIYVYSEGMLELEDTFSTIMVTADSDKHEIVPECVLNYFRKNLELFRNALE-IKRIL-- 253
Query: 157 GAAAKILRELEGIEDVMRRNERLENIEEIIRRYESELNKRIEEKLERFKLTLSGKELVEF 216
G + +E ++++ +I+E++ ++ + ++ + ++ + LSG E++
Sbjct: 254 GMETCLHEVVEIMDELQAAGGEEVDIDEVVNSVKAWADMKLRDLIK--DIDLSGDEVLTL 311
Query: 217 LRSLRYGDVEAILSKFSSLNDDIIEEIRKAEEKLSQELGVAIEVFPRDYPVEVPPDVVER 276
L + + +K + DD++ E R +K S GV + F + YP+++ VER
Sbjct: 312 LN-------QGMTAKLERIFDDVLSEARSMIKKRS---GVEFDPFIKSYPLKIDQREVER 361
Query: 277 LKRSVERELKIELYMRAREIVPRIIPYIQGLKEEIERAYELEFILALKRFSRGFTFPKIE 336
+KR + + + R+ ++ EI E ++ LAL F+ + + E
Sbjct: 362 VKRLEAASRNLREFEVKVDAATRLGELRGAVEGEIRDIMEFDYRLALGLFAHEYELTEPE 421
Query: 337 EGGIGFIKGR---NLF-IENPQPVSYFVGSAKGQFKGIQESSVVILTGANSGGKTSLLEL 392
G ++G NL PQ V Y +G +VV+LTGANSGGKT+LLE
Sbjct: 422 FGDEISLRGALHLNLVGSRKPQRVDYRIGDP---------DNVVLLTGANSGGKTTLLET 472
Query: 393 MLQIVILAHMGLPVPASEAWVEPLDEVFFFKRKRINYGAGAFESSLKSIVKALKGKGRKL 452
+ Q+ I+A MGLPV A EA V +DEV+F +KR + AGAFES +++ + KL
Sbjct: 473 LAQVTIMAQMGLPVCALEACVRVVDEVYFISKKR-SLDAGAFESFIRTFTPVTTSENSKL 531
Query: 453 ILIDEFEAITEPGAAAKILAELLKIGVEKGFYIVIVSHLGEDLKKELPYARVDGIEASGL 512
IL+DE EAITE AA KI+A ++ E VIV+H+ ++ K + RVDGIEA GL
Sbjct: 532 ILLDELEAITELEAAVKIIATFIEFIGESSSLAVIVTHMAREIMKYVD-VRVDGIEARGL 590
Query: 513 DEELNLIVDRQPKFGVIGKSTPELILERLARKGRGEEREILMKVLAKLNNT 563
D++ NLIVDR P+ + +STPELI+ + K +ER + ++L K T
Sbjct: 591 DDDYNLIVDRTPRINYLARSTPELIIRMIYEKSSDDERIVYGRILEKFQKT 641
>gb|AAG20386.1| (AE005111) mismatch repair protein; MutS3 [Halobacterium sp. NRC-1]
Length = 669
Score = 174 bits (437), Expect = 2e-42
Identities = 161/599 (26%), Positives = 274/599 (44%), Gaps = 82/599 (13%)
Query: 9 AREIYRAIRRKIESEIRVSEAKRFLDNFEPVSDVGEILKRQNYLKRAMESVS-EEVEGLL 67
A EI+ + ++ A++ L F P + I + ++ AM+ ++V L
Sbjct: 70 AAEIHERVLGLLQERAVTEYARQRLRTFYPSAADSRIAEVNAFVADAMQRTPRDDVLEAL 129
Query: 68 LKVKPIKFRKEF-LGDRLLVVSEDEVEEAEKLGLCMVSTEPIE----------GYDIV-- 114
V+P+ + +R + ++ E +S E +E GY V
Sbjct: 130 AGVEPLSAPSGVSVRERCVATTDAETYSDAAAAFPELSVEIVEDARDLAELARGYTTVVA 189
Query: 115 LSTIGYGIDVE----------LKPYEIAPELYIKPLWESRDVLEALARIFPG-------- 156
L G++VE +P E+ PE + +RD + A +
Sbjct: 190 LDEAFVGVEVEGDVRVEPDAMERPAEVVPERVLSFFAANRDRIRAAVSVHEAAGIDTDVD 249
Query: 157 -----GAAAKILRE--LEGIEDVMRRNERLENIEEIIRRYESELNKRIEEKLERFKLTLS 209
GA A + + + G +++ R + +++ + ES N R+ E + +T+
Sbjct: 250 LDALDGALAHLEGDGSVAGDDELDRLTRAVNDLDAAVSDAESVANDRLREAIGEQDVTIE 309
Query: 210 GKELVEFLRSLRYGDVEAILSKFSSLNDDIIEEIRKAEEKLSQELGV-------AIEVFP 262
G +L+ + R V+++L + L D+ + + A + L ++LG+ A VF
Sbjct: 310 GADLLSLVE--RGAGVDSLLGR--ELADEYDDAVGAARDALEEQLGLRGEAAKLARRVFG 365
Query: 263 RD--YPVEVPPDVVERLKRSVERELKIELYMRAREIVPRIIPYIQGLKEEIERAYELEFI 320
+ +PV D + R++ S+ R RE+ + + + A E++
Sbjct: 366 DEPTFPVARDDDAMARVRESLTAARDRRAAGRKRELAATLADLRAPTEALVHDALEVDVA 425
Query: 321 LALKRFSRGFTFPKIEEGGIGFI--KGRNLFIE----NPQPVSYFVGSAKGQFKGIQESS 374
LA+ RF+ F E GG GF GRN ++ +PV Y V
Sbjct: 426 LAVARFAADFDCVLAERGGRGFRIEGGRNPLLDVAFAETEPVEYGV------------DG 473
Query: 375 VVILTGANSGGKTSLLELMLQIVILAHMGLPVPASEAWVEPLDEVFFFKRKRINYGAGAF 434
V +L+G NSGGKTS L+L+ +V+LAHMGLPVPA A V + E+ ++ + + AGAF
Sbjct: 474 VALLSGVNSGGKTSTLDLVAVVVVLAHMGLPVPAEAARVPAIAELHYYAKSQGTLDAGAF 533
Query: 435 ESSLKSIVKAL----------KGKGRKLILIDEFEAITEPGAAAKILAELLKIGVEKGFY 484
E++L+ + +L+L+DE E+ITEPGA+AKI+A +L+ E G
Sbjct: 534 EATLRDFASLTERVADDEGGEESAASRLVLVDELESITEPGASAKIIAGILEALHEAGAS 593
Query: 485 IVIVSHLGEDLKKELPY-ARVDGIEASGLDEELNLIVDRQPKFGVIGKSTPELILERLA 542
V VSHL +++ + + VDGI A+GL E+ L+V+R P + +STPELI+E+LA
Sbjct: 594 GVFVSHLAGEIRDQCGFGVTVDGIHAAGL-EDGELVVERSPVKDHLARSTPELIVEKLA 651
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.318 0.141 0.382
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 201464822
Number of Sequences: 2977
Number of extensions: 8888109
Number of successful extensions: 33620
Number of sequences better than 1.0e-10: 4
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 33610
Number of HSP's gapped (non-prelim): 4
length of query: 570
length of database: 189,106,746
effective HSP length: 60
effective length of query: 510
effective length of database: 153,197,526
effective search space: 78130738260
effective search space used: 78130738260
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 167 (69.5 bits)