BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1312 (RAD25) DE:DNA repair protein RAD25
         (453 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||B75006 DNA repair protein rad25 PAB1312 - Pyrococcus abyssi...   897  0.0
pir||C71156 probable helicase protein PH0450 - Pyrococcus horiko...   785  0.0
gi|11497970 DNA repair protein RAD25 [Archaeoglobus fulgidus] >g...   535  e-151
gb|AAK40796.1| DNA repair protein rad25 [Sulfolobus solfataricus]     409  e-113
gi|10803640 ORF H1047 [Halobacterium sp. NRC-1] >gi|7446116|pir|...   367  e-100
emb|CAC12145.1| (AL445066) DNA repair protein RAD25 related prot...   337  2e-91
gb|AAF69763.1| (AF068771) similar to RAD25 [Synechocystis PCC9413]    295  7e-79
pir||B72707 hypothetical protein APE1073 - Aeropyrum pernix (str...   276  4e-73
gb|AAK41233.1| DNA repair protein rad25 [Sulfolobus solfataricus]     273  2e-72
pir||E70815 hypothetical protein Rv0861c - Mycobacterium tubercu...   160  3e-38
pir||F71330 probable DNA repair helicase - syphilis spirochete >...   153  5e-36
pir||H71243 probable helicase protein PH0210 - Pyrococcus horiko...   129  5e-29
gb|AAC49987.1| (U29168) putative DNA repair protein and transcri...   127  3e-28
gb|AAG27465.1|AF308595_1 (AF308595) putative DNA repair protein ...   127  3e-28
dbj|BAB08508.1| (AB006707) DNA excision repair cross-complementi...   127  3e-28
pir||A75209 DNA repair protein rad25 PAB0128 - Pyrococcus abyssi...   124  2e-27
pir||S71206 DNA excision repair cross-complementing protein ERCC...   124  2e-27
gb|AAG19725.1| (AE005058) putative DNA helicase; Rhl [Halobacter...   119  7e-26
gb|AAB62732.1| (U77065) RepB [Dictyostelium discoideum]               116  5e-25
gi|4557563 excision repair cross-complementing rodent repair def...   113  6e-24
sp|P49135|XPB_MOUSE DNA-REPAIR PROTEIN COMPLEMENTING XP-B CELLS ...   112  7e-24
pir||T31655 DNA excision repair cross-complementing protein - se...   110  4e-23
sp|Q02870|XPB_DROME DNA EXCISION REPAIR PROTEIN HAYWIRE (ERCC-3 ...   109  6e-23
gb|AAF50150.1| (AE003547) hay gene product [Drosophila melanogas...   109  6e-23
pir||A44223 DNA excision repair cross-complementing protein ERCC...   109  8e-23
emb|CAA76655.1| (Y17148) XPB protein [Geodia cydonium]                109  8e-23
gb|AAA34942.1| (L01414) DNA helicase [Saccharomyces cerevisiae]       108  1e-22
gi|6322048 DNA helicase homolog; homolog of human XPBC, ERCC3; S...   108  1e-22
gb|AAA74931.1| (L02965) helicase [Drosophila melanogaster]            105  1e-21
pir||T37821 probable dna repair helicase - fission yeast  (Schiz...   102  6e-21
gi|11429283 excision repair cross-complementing rodent repair de...    78  2e-13
emb|CAA67095.1| (X98455) SNF [Bacillus cereus]                         71  2e-11
gi|6320539 Ydr332wp [Saccharomyces cerevisiae] >gi|2131433|pir||...    71  2e-11
pir||E71481 probable swf/snf helicase - Chlamydia trachomatis (s...    71  3e-11
emb|CAB93078.1| (AL357432) putative helicase (fragment) [Strepto...    69  1e-10

>pir||B75006 DNA repair protein rad25 PAB1312 - Pyrococcus abyssi (strain Orsay)
           >gi|5459002|emb|CAB50488.1| (AJ248288) DNA repair
           protein RAD25 [Pyrococcus abyssi]
           Length = 453
           
 Score =  897 bits (2294), Expect = 0.0
 Identities = 453/453 (100%), Positives = 453/453 (100%)

Query: 1   MKLYYDRGTIKVIGNSYVPYARWDERCRCYRALAYKYRDIVEFLESEGIEFEDYVLENAL 60
           MKLYYDRGTIKVIGNSYVPYARWDERCRCYRALAYKYRDIVEFLESEGIEFEDYVLENAL
Sbjct: 1   MKLYYDRGTIKVIGNSYVPYARWDERCRCYRALAYKYRDIVEFLESEGIEFEDYVLENAL 60

Query: 61  PSRVYDDVEFELRDYQEEAVERWMREKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPT 120
           PSRVYDDVEFELRDYQEEAVERWMREKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPT
Sbjct: 61  PSRVYDDVEFELRDYQEEAVERWMREKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPT 120

Query: 121 LALLEQWKERLEIFGDVGEFSGRKKELKPITVTTYDSAYINAEFLGDKFFLLIFDECHHL 180
           LALLEQWKERLEIFGDVGEFSGRKKELKPITVTTYDSAYINAEFLGDKFFLLIFDECHHL
Sbjct: 121 LALLEQWKERLEIFGDVGEFSGRKKELKPITVTTYDSAYINAEFLGDKFFLLIFDECHHL 180

Query: 181 PSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELMGTYLAPYEL 240
           PSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELMGTYLAPYEL
Sbjct: 181 PSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELMGTYLAPYEL 240

Query: 241 VRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALE 300
           VRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALE
Sbjct: 241 VRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALE 300

Query: 301 EARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERV 360
           EARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERV
Sbjct: 301 EARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERV 360

Query: 361 EILRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKER 420
           EILRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKER
Sbjct: 361 EILRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKER 420

Query: 421 AILYELITPGTTEVRISSRRLSGIKKLESLDDL 453
           AILYELITPGTTEVRISSRRLSGIKKLESLDDL
Sbjct: 421 AILYELITPGTTEVRISSRRLSGIKKLESLDDL 453


>pir||C71156 probable helicase protein PH0450 - Pyrococcus horikoshii
           >gi|3256853|dbj|BAA29536.1| (AP000002) 449aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 449
           
 Score =  785 bits (2006), Expect = 0.0
 Identities = 378/447 (84%), Positives = 422/447 (93%)

Query: 1   MKLYYDRGTIKVIGNSYVPYARWDERCRCYRALAYKYRDIVEFLESEGIEFEDYVLENAL 60
           MKLYYDRGTIK+IG+SYVP+ARWDERC CYRALAYKYRDIVEFL+SEG++FED+VL+N +
Sbjct: 1   MKLYYDRGTIKIIGSSYVPFARWDERCNCYRALAYKYRDIVEFLKSEGVDFEDHVLDNVI 60

Query: 61  PSRVYDDVEFELRDYQEEAVERWMREKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPT 120
           PS  Y+DVEFELRDYQ EAVERWM EKRG+IVLPTG+GKTI+AMEI++RLS+STLV+VPT
Sbjct: 61  PSPFYEDVEFELRDYQREAVERWMMEKRGIIVLPTGSGKTIIAMEIMRRLSVSTLVVVPT 120

Query: 121 LALLEQWKERLEIFGDVGEFSGRKKELKPITVTTYDSAYINAEFLGDKFFLLIFDECHHL 180
           LALLEQWKERL IFG+VGEFSG+KKELKPITVTTYDSAYINAE LGDKF L+IFDECHHL
Sbjct: 121 LALLEQWKERLSIFGEVGEFSGKKKELKPITVTTYDSAYINAELLGDKFMLIIFDECHHL 180

Query: 181 PSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELMGTYLAPYEL 240
           P+EAYRNIAQMS APYRLGLTAFPER+DNLH+LLPDLIGP+VYKK P EL+GTYLAPYE+
Sbjct: 181 PAEAYRNIAQMSVAPYRLGLTAFPERSDNLHELLPDLIGPVVYKKGPGELIGTYLAPYEI 240

Query: 241 VRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALE 300
           VR+KVPLSREER EY K+Y +FKRYL ESG+ IKSLEDFQ+IVM+TG+DNKAFKALRALE
Sbjct: 241 VRIKVPLSREEREEYKKYYGIFKRYLEESGIEIKSLEDFQRIVMKTGMDNKAFKALRALE 300

Query: 301 EARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERV 360
           ++RKIALGSK KIEELRKILERHRGEKIII TRYNELVYEISRKFLIPAITHKT K+ER 
Sbjct: 301 KSRKIALGSKGKIEELRKILERHRGEKIIIFTRYNELVYEISRKFLIPAITHKTDKKERS 360

Query: 361 EILRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKER 420
           EIL+KFR+G Y AVVSSQVLDEGIDVPDASVG+IISGTGSPREL+QRLGRILR APGKE+
Sbjct: 361 EILKKFRKGIYKAVVSSQVLDEGIDVPDASVGVIISGTGSPRELIQRLGRILRSAPGKEK 420

Query: 421 AILYELITPGTTEVRISSRRLSGIKKL 447
           AILYEL+TPGT EVRI+SRRLSG+KKL
Sbjct: 421 AILYELVTPGTAEVRIASRRLSGLKKL 447


>gi|11497970 DNA repair protein RAD25 [Archaeoglobus fulgidus]
           >gi|7446073|pir||F69294 DNA repair protein RAD25 homolog
           - Archaeoglobus fulgidus >gi|2650278|gb|AAB90879.1|
           (AE001080) DNA repair protein RAD25 [Archaeoglobus
           fulgidus]
           Length = 452
           
 Score =  535 bits (1363), Expect = e-151
 Identities = 271/446 (60%), Positives = 347/446 (77%), Gaps = 4/446 (0%)

Query: 2   KLYYDRGTIKVIGNSYVPYARWDERCRCYRALAYKYRDIVEFLESEGIEFEDYVLENALP 61
           ++YY+RGTI V G+++VP+A++D R   YRALA++YRDI+E+ ES GIEF D   +  +P
Sbjct: 6   EIYYERGTIVVKGDAHVPHAKFDSRSGTYRALAFRYRDIIEYFESNGIEFVDNAAD-PIP 64

Query: 62  SRVYDDVEFELRDYQEEAVERWMREKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTL 121
           +  Y D E  LRDYQE+A+ERW+ +KRG IVLPTG+GKT VAM  I  LS  TL++VPTL
Sbjct: 65  TP-YFDAEISLRDYQEKALERWLVDKRGCIVLPTGSGKTHVAMAAINELSTPTLIVVPTL 123

Query: 122 ALLEQWKERLEIFGD--VGEFSGRKKELKPITVTTYDSAYINAEFLGDKFFLLIFDECHH 179
           AL EQWKERL IFG+  VGEFSGR KELKP+TV+TYDSAY+NAE LG++F LLIFDE HH
Sbjct: 124 ALAEQWKERLGIFGEEYVGEFSGRIKELKPLTVSTYDSAYVNAEKLGNRFMLLIFDEVHH 183

Query: 180 LPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELMGTYLAPYE 239
           LP+E+Y  IAQMS AP+RLGLTA  ER D  H++L +++G  V++  P  L G +LA Y 
Sbjct: 184 LPAESYVQIAQMSIAPFRLGLTATFEREDGRHEILKEVVGGKVFELFPDSLAGKHLAKYT 243

Query: 240 LVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRAL 299
           + R+ VPL+ +ER EY K  KV+K++L   G+ ++  EDF KIVM +G D +A++ALRA 
Sbjct: 244 IKRIFVPLAEDERVEYEKREKVYKQFLRARGITLRRAEDFNKIVMASGYDERAYEALRAW 303

Query: 300 EEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEER 359
           EEAR+IA  SK KI +LR+ILERHR +KIII TR+NELVY IS+ FLIPAITH+TS+EER
Sbjct: 304 EEARRIAFNSKNKIRKLREILERHRKDKIIIFTRHNELVYRISKVFLIPAITHRTSREER 363

Query: 360 VEILRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKE 419
            EIL  FR G++ A+VSSQVLDEGIDVPDA+VG+I+SG+GS RE +QRLGRILRP+ GK+
Sbjct: 364 EEILEGFRTGRFRAIVSSQVLDEGIDVPDANVGVIMSGSGSAREYIQRLGRILRPSKGKK 423

Query: 420 RAILYELITPGTTEVRISSRRLSGIK 445
            A+LYELI+ GT EV  + RR +  K
Sbjct: 424 EAVLYELISRGTGEVNTARRRKNAAK 449


>gb|AAK40796.1| DNA repair protein rad25 [Sulfolobus solfataricus]
           Length = 444
           
 Score =  409 bits (1041), Expect = e-113
 Identities = 212/424 (50%), Positives = 293/424 (69%), Gaps = 5/424 (1%)

Query: 19  PYARWDERCRCYRALAYKYRDIVEFLESEGIEFEDYVLENALPSRVYDDVEFELRDYQEE 78
           P   W++  +CY   A KYR+++ + +   +E ED VLE  LP  +  D   +LR+YQ+E
Sbjct: 18  PGLSWNDEFKCYIGQANKYREVLYYYKRSHVEVEDSVLE-LLPFPLIVD-RIKLREYQQE 75

Query: 79  AVERWMREKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWKERL-EIFG-D 136
           A+  W++ K G+IV+PTG GKT++ ++ I  + L+TL+IVPT+ LL+QW E + E+ G +
Sbjct: 76  ALNAWLKSKLGIIVIPTGGGKTVIGLKAIALIRLATLIIVPTIDLLQQWYENIRELLGVE 135

Query: 137 VGEFSGRKKELKPITVTTYDSAYINAEFLGDKFFLLIFDECHHLPSEAYRNIAQMSAAPY 196
            G   G   ELK ITV TYDSAY   E +G+KF L+IFDE HHLPSE Y  IAQ  AAPY
Sbjct: 136 AGRVGGGYDELKGITVITYDSAYTQLEKIGNKFGLVIFDEVHHLPSEGYSIIAQGLAAPY 195

Query: 197 RLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELMGTYLAPYELVRVKVPLSREERAEYL 256
           RLGLTA PER+D  H L P L+GP+VY+     L+G YL+ +E+ R+ V L+ +E   Y 
Sbjct: 196 RLGLTATPERSDGRHKLYPSLVGPLVYRITVSNLVGKYLSSFEIQRIYVNLTEDEEKLYR 255

Query: 257 KHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKIALGSKAKIEEL 316
            +  + K++LS+  L++KSL DF +++     D +A +AL A  EA KIA+ SKAK+E+L
Sbjct: 256 HYRGILKKFLSQRNLKLKSLNDFNRLLRLAVKDKEAREALLAWHEALKIAVNSKAKLEKL 315

Query: 317 RKILERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERVEILRKFREGKYMAVVS 376
           + +L+   GEKIII TR   +VYEISR FLIPA+T+KT+K+ER+EIL KFR GKY  +V+
Sbjct: 316 KDLLKELNGEKIIIFTRNTSMVYEISRLFLIPAVTYKTNKQERIEILEKFRSGKYNVIVT 375

Query: 377 SQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKERAILYELITPGTTEVRI 436
           S VLDEGIDVPDAS+GI++ G G+ R+ +QRLGRILR    K +A L E+IT GT++  +
Sbjct: 376 SSVLDEGIDVPDASIGIVLGGYGTSRQFIQRLGRILRKKENK-KARLIEIITKGTSDYNL 434

Query: 437 SSRR 440
           S RR
Sbjct: 435 SKRR 438


>gi|10803640 ORF H1047 [Halobacterium sp. NRC-1] >gi|7446116|pir||T08310
           helicase homolog H1047 - Halobacterium sp. (strain
           NRC-1) plasmid pNRC100 >gi|2822371|gb|AAC82877.1|
           (AF016485) ORF H1047 [Halobacterium sp. NRC-1]
           >gi|10584184|gb|AAG20805.1| (AE005148) DNA repair
           protein; Rad25 [Halobacterium sp. NRC-1]
           Length = 469
           
 Score =  367 bits (933), Expect = e-100
 Identities = 203/463 (43%), Positives = 290/463 (61%), Gaps = 19/463 (4%)

Query: 1   MKLYYDRGTIKVI-GNSYVPYARWDERCRCYRALAYKYRDIVEFLE--------SEGIEF 51
           M+L +D GT+ +    + VPYA WD+R   YRA A  Y+D+ ++ +        ++    
Sbjct: 1   MRLAFDDGTLLLEDAPNSVPYADWDDRVDEYRARALHYQDLCQWAQGPDGQATLNQASHT 60

Query: 52  EDYVLENALPSRVYD---DVEFELRDYQEEAVERWM-REKRGVIVLPTGAGKTIVAMEII 107
           ++ + ++A   R  D    V  E RDYQ+ A+  W   ++RG +VLPTG+GKT +A++ I
Sbjct: 61  DESLHDDARAYRDLDLTPAVAIEPRDYQQAALAAWTDHDRRGSVVLPTGSGKTFLAVQAI 120

Query: 108 KRLSLSTLVIVPTLALLEQWKERL-EIFGD-----VGEFSGRKKELKPITVTTYDSAYIN 161
              S+STLV+VPT+ LL QW   L   FGD     +G   G    +  ITVTTYDSAY  
Sbjct: 121 ADASVSTLVVVPTIDLLNQWHATLTNAFGDQLPHEIGVLGGGSHNVTDITVTTYDSAYRY 180

Query: 162 AEFLGDKFFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPI 221
               GD+F LL+ DE HHLP+  Y+ I +M+ APYRLGLTA  ER D  H++L DLIGP+
Sbjct: 181 INEYGDQFGLLVVDEVHHLPAPTYQQIPEMTIAPYRLGLTATYERTDGEHNVLEDLIGPV 240

Query: 222 VYKKAPRELMGTYLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQK 281
           VY++   EL G YL+ YE + +KV L+ EER +Y   Y++++ YL    + I   + +Q+
Sbjct: 241 VYEENVDELAGEYLSEYETIHLKVDLTPEERNQYDDEYQIYRDYLDNHDVDIWKQDGYQE 300

Query: 282 IVMRTGVDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEI 341
            + RT  D    +AL A + A +IA  ++ K++ L  +L+RH  ++ II T  N+  Y+I
Sbjct: 301 FLKRTSYDPDGRRALIAKQRAEEIARTAEKKLDTLDNLLKRHYNDRTIIFTANNDFAYDI 360

Query: 342 SRKFLIPAITHKTSKEERVEILRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSP 401
           S++F++P ITH+T  +ER EIL +FR G+Y  +V+SQVLDEGIDVP A+VGII+SG+ S 
Sbjct: 361 SQEFIVPCITHQTQTDERTEILERFRTGEYSMLVTSQVLDEGIDVPAANVGIILSGSASK 420

Query: 402 RELVQRLGRILRPAPGKERAILYELITPGTTEVRISSRRLSGI 444
           R+  QRLGRILRP   +E A LYELIT  T E  +S RR  G+
Sbjct: 421 RQYAQRLGRILRPTEDREPARLYELITDDTMEQYVSKRRRQGV 463


>emb|CAC12145.1| (AL445066) DNA repair protein RAD25 related protein [Thermoplasma
           acidophilum]
           Length = 453
           
 Score =  337 bits (854), Expect = 2e-91
 Identities = 191/448 (42%), Positives = 279/448 (61%), Gaps = 12/448 (2%)

Query: 3   LYYDRGTIKVIG---NSYVPYARWDERCRCYRALAYKYRDIVEFLESEGIEFEDYVLENA 59
           + Y  G+I + G   N     A +D R  CYR+L   Y  I+ F    GI+  D V++  
Sbjct: 4   IVYSGGSILIKGYDGNIPEDLAVFDHRIACYRSLGVNYPRILSFFRDAGIDAVDRVMDR- 62

Query: 60  LPSRVYDDVEFELRDYQEEAVERWMRE-KRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIV 118
               +  +    LR YQ +A+E W +   RG +VLPT AGKT + M  I+ +S   L++V
Sbjct: 63  --KHLNLNGRISLRPYQLQALEEWKKYGMRGTVVLPTAAGKTHIGMAAIQAVSERALILV 120

Query: 119 PTLALLEQWKERL-EIFG-DVGEFSGRKKELKPITVTTYDSAYINAEFLGDKFFLLIFDE 176
           PT+ LL QWK+R+ E FG + G+  G + + + ITV+TYDSAY+ AE  G++F L+I DE
Sbjct: 121 PTIDLLSQWKKRIQETFGVEPGQIGGGEHDERDITVSTYDSAYLMAEKYGNRFSLIIADE 180

Query: 177 CHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELMGTYLA 236
            HHL SE  R I  M  AP+R+GLTA  ER D L  +L  ++G  +++    E+   YLA
Sbjct: 181 VHHLASEKLRMIPLMYTAPFRMGLTATYERTDGLQKVLEQIMGGKIFELGYEEI-DEYLA 239

Query: 237 PYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKAL 296
            Y + R+ + LS EE A+Y +++++F  YL    + ++   DF+K + R+    +  +AL
Sbjct: 240 DYTIARIPIELSDEEYADYQRYHEIFVSYLRRHRMVMRGPWDFEKFI-RSSWTPEGREAL 298

Query: 297 RALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSK 356
            A  ++R+IA  S+ K+E +R IL +HRGEK +I     E  Y IS++FLIPAIT+ T K
Sbjct: 299 IAWRKSREIAFNSRGKMEMIRTILSKHRGEKTLIFAEDTETAYTISKEFLIPAITYLTDK 358

Query: 357 EERVEILRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAP 416
           EER +I   FREG+  A+ +S+VLDEG+D PDASV I++SG+GS R+  QRLGRILRP+ 
Sbjct: 359 EEREKIPAMFREGRITAIATSRVLDEGVDFPDASVAIVVSGSGSMRQFRQRLGRILRPSA 418

Query: 417 GKERAILYELITPGTTEVRISSRRLSGI 444
           GK +A++YEL+T  T+E  +S RR  G+
Sbjct: 419 GK-KAVMYELVTAETSEFGVSRRRRKGV 445


>gb|AAF69763.1| (AF068771) similar to RAD25 [Synechocystis PCC9413]
           Length = 449
           
 Score =  295 bits (747), Expect = 7e-79
 Identities = 168/377 (44%), Positives = 236/377 (62%), Gaps = 7/377 (1%)

Query: 71  ELRDY--QEEAVERWMREKR-GVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQW 127
           E+R Y  Q EA++ W    R G++VLPT AGKT +A   ++    STL++VPTL L+ QW
Sbjct: 26  EMRPYAHQSEALQAWKEAGRQGIVVLPTAAGKTYLAQLAMQATPRSTLIVVPTLDLMHQW 85

Query: 128 -KERLEIFGD--VGEFSGRKKELKPITVTTYDSAYINAEFLGDKFFLLIFDECHHLPSEA 184
             + L  F D  +G   G  ++   I V TYDSA I+AE LG ++   IFDECHHLP++ 
Sbjct: 86  YAQLLAAFPDAEIGLLGGGSRDRTSILVATYDSAAIHAESLGSQYAFAIFDECHHLPTDF 145

Query: 185 YRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELMGTYLAPYELVRVK 244
           YR IA+ S APYRLGLTA  ER+D     L +LIG IVY+K P EL GT LA +++ ++K
Sbjct: 146 YRPIAEYSIAPYRLGLTATIERSDGRDRDLLNLIGDIVYQKTPEELAGTALAHHKIAQIK 205

Query: 245 VPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARK 304
           V LS  ER  Y +  +    +L    + + S+E ++  V  +       +A+ A  +AR+
Sbjct: 206 VKLSVRERETYQRLIQERNEFLRSQNISLGSMEGWKMFVQASARSAAGRRAMLAHRQARE 265

Query: 305 IALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERVEILR 364
           IAL +  K+  L  +L +H  E  II T  N  VY+IS+  LIPAITH+T  +ER EIL 
Sbjct: 266 IALITDGKLRVLINLLGQHYPESTIIFTADNATVYKISKALLIPAITHQTPVKERHEILT 325

Query: 365 KFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPG-KERAIL 423
           +F+ G Y  +++S VL+EG+DVP+A + I++SGTGS RE +QRLGR+LR     +++AIL
Sbjct: 326 RFKAGDYKTLIASHVLNEGVDVPEARIAIVLSGTGSRREYIQRLGRVLRKGQNDQKQAIL 385

Query: 424 YELITPGTTEVRISSRR 440
           YE+I   T E   S+RR
Sbjct: 386 YEVIAEDTVEEGTSARR 402


>pir||B72707 hypothetical protein APE1073 - Aeropyrum pernix (strain K1)
           >gi|5104743|dbj|BAA80058.1| (AP000060) 539aa long
           hypothetical protein [Aeropyrum pernix]
           Length = 539
           
 Score =  276 bits (698), Expect = 4e-73
 Identities = 178/432 (41%), Positives = 248/432 (57%), Gaps = 22/432 (5%)

Query: 23  WDERCRCYRALAYKYRDIVEFLESEGIEFEDYVL---ENALPSRVYDDVEFELRDYQEEA 79
           +D   R YRA    Y  + E  E  G++ ED V      +LP  V      ELRDYQEEA
Sbjct: 117 YDREARAYRAPPIMYPRLREAFERRGLKVEDRVFPPSSRSLPRPVR--FTGELRDYQEEA 174

Query: 80  VERWMREK-RGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWKERLEIFGD-- 136
           +E W +   RGVIVLPTGAGKT+VA+  +    + +L++V T   + QW +    F D  
Sbjct: 175 LEAWRKAGGRGVIVLPTGAGKTVVAIAAVAWAGVWSLIVVYTRDHVRQWIDAFRRFTDAH 234

Query: 137 --VGEFSGRKKELKPITVTTYDSAYINAEFLGDKFFLLIFDECHHLPSEAYRNIAQMSAA 194
             VG + G +K L PITVTTY +AY + + L   F  L+FDE HH+P++ ++ IA  S A
Sbjct: 235 SLVGAYYGEEKRLAPITVTTYQTAYRHIDRLAPLFPFLVFDEAHHIPADKFKRIASASPA 294

Query: 195 PYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELMGT-YLAPYELVRVKVPLSREERA 253
           PYR+GL+A  ER D  H+ +  L+G +VY  +P EL    YLAP+ + RVKV L  EE+ 
Sbjct: 295 PYRMGLSATIEREDGRHEEVYSLVGGVVYSSSPGELTRKGYLAPFVIRRVKVELEEEEKR 354

Query: 254 EYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKIALGSKAKI 313
            Y +  K   R L+      K LED ++       D  A +A+R     ++I   S++KI
Sbjct: 355 LY-EDLKRKYRILARGRSFEKILEDARR------GDPTAIEAIRVNTRMKEIVQLSESKI 407

Query: 314 EELRKIL--ERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERVEILRKFREGKY 371
             + K++  E  RG K+I+ T+Y     EI+R+     +     +  R   L KFR  K 
Sbjct: 408 RAVEKLVREELSRGSKVIVFTQYRRQAEEIARRTGALLLHGGLERRVREATLAKFRALKA 467

Query: 372 MAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKERAILYELITPGT 431
            A+V + V DEG+D+PDA+VGI++SGTGS R+ +QRLGR+LRP  GK RA+LYE+I  GT
Sbjct: 468 GALVVTTVGDEGLDIPDANVGILVSGTGSRRQFIQRLGRLLRPGEGK-RAVLYEVIARGT 526

Query: 432 TEVRISSRRLSG 443
            E  + SRR  G
Sbjct: 527 GE-ELQSRRRRG 537


>gb|AAK41233.1| DNA repair protein rad25 [Sulfolobus solfataricus]
           Length = 551
           
 Score =  273 bits (692), Expect = 2e-72
 Identities = 169/429 (39%), Positives = 254/429 (58%), Gaps = 26/429 (6%)

Query: 22  RWDERCRCYRALAYKYRDIVEFLESEGIEFEDYVLENALPSRVYDDVEFE----LRDYQE 77
           R+D++ R +      Y ++++ L   G+E ++  L        + + EFE    LR+YQ 
Sbjct: 117 RYDKQNRRFIVRPMDYFNLLQKLRENGLEVKELNLS-------FKEFEFEFNGQLREYQR 169

Query: 78  EAVERWMRE-KRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWKERLEIFG- 135
           EA+E W++   +GVI LPTGAGKT+V ++ I  +   TL++  T   + QWKE +  F  
Sbjct: 170 EAIENWIKNGNKGVIALPTGAGKTVVGIKGIDIIRKPTLIVTFTKEQMLQWKEAILKFTS 229

Query: 136 ---DVGEFSGRKKELKPITVTTYDSAYINAEFLGDKFFLLIFDECHHLPSEAYRNIAQMS 192
              D+G +   +K ++PIT+TTY +AY +   L DKF+LLI DE HHLP++ ++ IA+  
Sbjct: 230 KRPDIGLYYSEEKRIRPITITTYHTAYRHLPQLFDKFYLLIVDEVHHLPADKFKLIAEGL 289

Query: 193 AAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELMGT-YLAPYELVRVKVPLSREE 251
            APYR+GL+A P R DN H+ L  LIG I+Y K+  EL    YLA YE+++ KV L+ EE
Sbjct: 290 IAPYRMGLSATPHREDNKHNELFSLIGGIIYYKSVTELAKLGYLASYEIIQKKVRLTLEE 349

Query: 252 RAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKIALGSKA 311
           R  Y +    FK      G ++  L +  K       D  A +A+R   E RKI   +  
Sbjct: 350 RKRYNELLNRFKAL--SKGRKVSELIELVK-----KGDESAIEAMRVYNEMRKIVNFASE 402

Query: 312 KIEELRKILERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERVEILRKFREGKY 371
           K++ L +IL+  +G KI+I T+Y +   EI++++    +T K SKEER  +L  F+    
Sbjct: 403 KMKALDEILKSEKG-KILIFTQYIDQAEEIAKRYNSLLLTGKMSKEERKRVLVTFKTMNA 461

Query: 372 MAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKERAILYELITPGT 431
             +V + V DEGID+PDA+VGII++GT S R+ +QRLGRI+RP  GK+ A LYE++  GT
Sbjct: 462 GVLVLTTVGDEGIDIPDANVGIIVTGTSSRRQFIQRLGRIMRPYNGKQ-AKLYEIVVSGT 520

Query: 432 TEVRISSRR 440
            E   + +R
Sbjct: 521 PEEYQAKKR 529


>pir||E70815 hypothetical protein Rv0861c - Mycobacterium tuberculosis  (strain
           H37RV) >gi|2916920|emb|CAA17667.1| (AL022004)
           hypothetical protein Rv0861c [Mycobacterium
           tuberculosis]
           Length = 542
           
 Score =  160 bits (401), Expect = 3e-38
 Identities = 119/402 (29%), Positives = 188/402 (46%), Gaps = 56/402 (13%)

Query: 54  YVLENALPSRVYDDVEFELRDYQEEAVERWMREKRGVIVLPTGAGKTIVAMEIIKRLSLS 113
           YV   A P  ++ +  ++LRDYQ  A + +     GV+VLP GAGKT+V    + +   +
Sbjct: 158 YVDGEAHPISLHQE-GWQLRDYQRLAADSFWAGGSGVVVLPCGAGKTLVGAAAMAKAGAT 216

Query: 114 TLVIVPTLALLEQWKERLE-----IFGDVGEFSGRKKELKPITVTTYD-------SAYIN 161
           TL++V  +    QWK  L         ++GEFSG +KE++P+T++TY          Y +
Sbjct: 217 TLILVTNIVAARQWKRELVARTSLTENEIGEFSGERKEIRPVTISTYQMITRRTKGEYRH 276

Query: 162 AEFLGDK-FFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGP 220
            E    + + L+I+DE H LP+  +R  A +  +  RLGLTA   R D     +  LIGP
Sbjct: 277 LELFDSRDWGLIIYDEVHLLPAPVFRMTADLQ-SKRRLGLTATLIREDGREGDVFSLIGP 335

Query: 221 IVYKKAPRELMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDF 279
             Y    +++    ++AP E V V+V ++  ER  Y                        
Sbjct: 336 KRYDAPWKDIEAQGWIAPAECVEVRVTMTDSERMMY------------------------ 371

Query: 280 QKIVMRTGVDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVY 339
                          A    EE  +I      KI  ++ IL +H  E+ ++   Y + + 
Sbjct: 372 ---------------ATAEPEERYRICSTVHTKIAVVKSILAKHPDEQTLVIGAYLDQLD 416

Query: 340 EISRKFLIPAITHKTSKEERVEILRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGT- 398
           E+  +   P I   T   ER  +   FR G+   +V S+V +  ID+P+A+V + +SGT 
Sbjct: 417 ELGAELGAPVIQGSTRTSEREALFDAFRRGEVATLVVSKVANFSIDLPEAAVAVQVSGTF 476

Query: 399 GSPRELVQRLGRILRPAPGKERAILYELITPGTTEVRISSRR 440
           GS +E  QRLGRILRP      AI Y ++   + +   ++ R
Sbjct: 477 GSRQEEAQRLGRILRPKADGGGAIFYSVVARDSLDAEYAAHR 518


>pir||F71330 probable DNA repair helicase - syphilis spirochete
           >gi|3322660|gb|AAC65366.1| (AE001217) DNA repair
           helicase, putative [Treponema pallidum]
           Length = 606
           
 Score =  153 bits (382), Expect = 5e-36
 Identities = 117/393 (29%), Positives = 194/393 (48%), Gaps = 64/393 (16%)

Query: 70  FELRDYQEEAVERWMREKR-----GVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALL 124
           F  RDYQ EA + ++  +      GV+VLP GAGKT+V + ++  L   TL++ P  A  
Sbjct: 235 FVPRDYQWEAADAFVGNRTQGSGFGVVVLPCGAGKTVVGLLVMGLLQTDTLILTPNSAAA 294

Query: 125 EQWK----ERLEIFG-DVGEFSGRKKELKPITVTTYD----SAYINAEFLGDKFF----- 170
           +QWK    E+ ++ G  +G +SG  KE++P+T+ TY      A+ +A F   + F     
Sbjct: 295 QQWKRELCEKTDLDGTSIGIYSGECKEIRPVTIATYQILTWRAHADAPFSHFRLFMERSW 354

Query: 171 -LLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRE 229
            L+I+DE H LP+  +R  A++     RLGLTA   R D     +  L+GP  Y    ++
Sbjct: 355 GLIIYDEVHLLPAPLFRITAELQVV-RRLGLTATLVREDGCAQDVFSLVGPKRYDVPWKD 413

Query: 230 LMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGV 288
           L    ++A    V V+V + R  + +Y+            + +R++              
Sbjct: 414 LEARGWIARVRCVEVRVTMDRSLQYQYM-----------TAPVRLR-------------- 448

Query: 289 DNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLIP 348
                          ++A  ++AK+  ++++L  H G   +I  +Y + +  ++    +P
Sbjct: 449 --------------HRLASENEAKVAVVQRLLRAHAGAPTLIIGQYVQQLLHLAHVLQVP 494

Query: 349 AITHKTSKEERVEILRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGT-GSPRELVQR 407
            ++ + +   R  I ++FREG    +V S+V +  +D+PDASV I +SGT GS +E  QR
Sbjct: 495 LVSGRQTYAAREAIYQRFREGTLQVLVVSKVANCALDLPDASVAIQVSGTFGSRQEEAQR 554

Query: 408 LGRILRPAPGKERAILYELITPGTTEVRISSRR 440
           LGR+LRP      A  Y L+T  T E   + RR
Sbjct: 555 LGRLLRPKICD--AHFYSLVTEQTVEEDCALRR 585


>pir||H71243 probable helicase protein PH0210 - Pyrococcus horikoshii
           >gi|3256596|dbj|BAA29279.1| (AP000001) 444aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 444
           
 Score =  129 bits (322), Expect = 5e-29
 Identities = 113/419 (26%), Positives = 197/419 (46%), Gaps = 55/419 (13%)

Query: 20  YARWDERCRCYRALAYKYR-----DIVEFLESEG--IEFEDYVLENALPSRVYDDVEFEL 72
           + RWD+    Y      +       + ++L S+G  +  +D  +    P     + E++L
Sbjct: 36  FGRWDKAESLYDPYTNTFPIGLLPRVKKYLNSKGYKVRVKDERVIEGEPLNSQWNEEYKL 95

Query: 73  RDYQEEAVERWMREKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWKERL- 131
           R YQ++AV+  ++EK GV+ LP G+GKT+V + II  ++ S LVIV T  LL QW  ++ 
Sbjct: 96  RKYQKKAVKLAIKEKMGVLALPVGSGKTVVGLRIIHEINKSALVIVHTKELLYQWANKVR 155

Query: 132 EIFG-DVGEFSGRKKELKPITVTTYDSAYI-NAEFLGDKFFLLIFDECHHL-PSEAYRNI 188
           EI G + G     K    PITV    +      + L +K+ +++FDECH    +E +  +
Sbjct: 156 EILGVEPGIIGDNKWSEGPITVAMIQTLLSRGTDKLQNKYAIVMFDECHRTSAAEKFYKV 215

Query: 189 AQMSAAPYRLGLTAFPERADNLHDL-LPDLIGPIVYKKAPRELMGTYLAPYELVRVKVPL 247
                  YR GL+A P R     ++ +  ++GPI+Y+    +L+                
Sbjct: 216 GISLPQVYRFGLSATPWRRLRGEEMKIEGVVGPIIYEVKAEDLI---------------- 259

Query: 248 SREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKIAL 307
             +E       ++V +       L  K  E +++ VM     N+A      +E+A ++A 
Sbjct: 260 --KEGFLAKPKFEVIEYDSKMPALADKYKELYEEAVMENEERNRAI-----VEKAIELA- 311

Query: 308 GSKAKIEELRKILERHRGEKIIISTR---YNELVYEISRKFLIPAITHKTSKEERVEILR 364
                           +G +++I  +   + E++ ++ R   I A    +    R EIL 
Sbjct: 312 ---------------KQGHRVLIDVKRIDHGEILVKMLRDRGINAEFLSSQSPNRWEILE 356

Query: 365 KFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKERAIL 423
           K+++G+   +VS+ +L EG+D+P+ S  I+  G  S    +Q +GR LRP PG E  I+
Sbjct: 357 KYKKGEIPVLVST-LLKEGVDIPEISAIILAGGGKSDVMTIQTIGRALRPKPGGEAVIV 414


>gb|AAC49987.1| (U29168) putative DNA repair protein and transcription factor
           [Arabidopsis thaliana] >gi|9758046|dbj|BAB08509.1|
           (AB006707) DNA excision repair cross-complementing
           protein; similar to human Xeroderma pigmentosum group B
           DNA repair protein [Arabidopsis thaliana]
           Length = 755
           
 Score =  127 bits (316), Expect = 3e-28
 Identities = 126/431 (29%), Positives = 196/431 (45%), Gaps = 80/431 (18%)

Query: 52  EDYVLENALPSRVYDDVEFEL------RDYQEEAVERWM---REKRGVIVLPTGAGKTIV 102
           E+Y   N     V  D++ EL      R YQE+++ +     R + G+IVLP GAGK++V
Sbjct: 247 EEYDFRN---DNVNPDLDMELKPHAQPRPYQEKSLSKMFGNGRARSGIIVLPCGAGKSLV 303

Query: 103 AMEIIKRLSLSTLVIVPTLALLEQWKERLEIFGDVGE-----FSGRKKEL----KPITVT 153
            +    R+  S L +      ++QW  + +++  + +     F+   KE       + VT
Sbjct: 304 GVSAAARIKKSCLCLATNAVSVDQWAFQFKLWSTIRDDQICRFTSDSKERFRGNAGVVVT 363

Query: 154 TY-----------DSAYINAEFLGDKFFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTA 202
           TY           +S  I  E    ++ LL+ DE H +P+  +R +  ++ +  +LGLTA
Sbjct: 364 TYNMVAFGGKRSEESEKIIEEMRNREWGLLLMDEVHVVPAHMFRKVISITKSHCKLGLTA 423

Query: 203 FPERADNLHDLLPDLIGPIVYKKAPRELM-GTYLAPYELVRVKVPLSREERAEYLKHYKV 261
              R D     L  LIGP +Y+    +L+ G ++A  +   V  P+++E  AEYLK    
Sbjct: 424 TLVREDERITDLNFLIGPKLYEANWLDLVKGGFIANVQCAEVWCPMTKEFFAEYLKK--- 480

Query: 262 FKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKIALGSKAKIEELRKILE 321
                          E+ +K      ++   F+A                  E L +  E
Sbjct: 481 ---------------ENSKKKQALYVMNPNKFRA-----------------CEFLIRFHE 508

Query: 322 RHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERVEILRKFREGKYM-AVVSSQVL 380
           + RG+KII+       + E + K   P I   TS  ER +IL  F+  K +  V  S+V 
Sbjct: 509 QQRGDKIIVFADNLFALTEYAMKLRKPMIYGATSHIERTKILEAFKTSKDVNTVFLSKVG 568

Query: 381 DEGIDVPDASVGIIISG-TGSPRELVQRLGRILRP--------APGKE--RAILYELITP 429
           D  ID+P+A+V I IS   GS R+  QRLGRILR         A GKE   A  Y L++ 
Sbjct: 569 DNSIDIPEANVIIQISSHAGSRRQEAQRLGRILRAKGKLEDRMAGGKEEYNAFFYSLVST 628

Query: 430 GTTEVRISSRR 440
            T E+  S++R
Sbjct: 629 DTQEMYYSTKR 639


>gb|AAG27465.1|AF308595_1 (AF308595) putative DNA repair protein and transcription factor
           [Arabidopsis thaliana]
           Length = 766
           
 Score =  127 bits (315), Expect = 3e-28
 Identities = 125/431 (29%), Positives = 196/431 (45%), Gaps = 80/431 (18%)

Query: 52  EDYVLENALPSRVYDDVEFEL------RDYQEEAVERWM---REKRGVIVLPTGAGKTIV 102
           E+Y   N     V  D++ EL      R YQE+++ +     R + G+IVLP GAGK++V
Sbjct: 259 EEYDFRN---DNVNPDLDMELKPHAQPRPYQEKSLSKMFGNGRARSGIIVLPCGAGKSLV 315

Query: 103 AMEIIKRLSLSTLVIVPTLALLEQWKERLEIFGDVGE-----FSGRKKEL----KPITVT 153
            +    R+  S L +      ++QW  + +++  + +     F+   KE       + VT
Sbjct: 316 GVSAAARIKKSCLCLATNAVSVDQWAYQFKLWSTIKDDQICRFTSDSKERFRGNAGVVVT 375

Query: 154 TY-----------DSAYINAEFLGDKFFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTA 202
           TY           ++  I  E    ++ LL+ DE H +P+  +R +  ++ +  +LGLTA
Sbjct: 376 TYNMIAFGGKRSEEAEKIIEEMRNREWGLLLMDEVHVVPAHMFRKVISITKSHCKLGLTA 435

Query: 203 FPERADNLHDLLPDLIGPIVYKKAPRELM-GTYLAPYELVRVKVPLSREERAEYLKHYKV 261
              R D     L  LIGP +Y+    +L+ G ++A  +   V  P+++E  AEYLK    
Sbjct: 436 TLVREDEKITDLNFLIGPKLYEANWLDLVKGGFIANVQCAEVWCPMTKEFFAEYLKK--- 492

Query: 262 FKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKIALGSKAKIEELRKILE 321
                          E+ +K      ++   F+A                  E L +  E
Sbjct: 493 ---------------ENSKKKQALYVMNPNKFRA-----------------CEFLIRFHE 520

Query: 322 RHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERVEILRKFREGKYM-AVVSSQVL 380
           + RG+KII+       + E + K   P I   TS  ER +IL  F+  K +  V  S+V 
Sbjct: 521 QQRGDKIIVFADNLFALTEYAMKLRKPMIYGATSHIERTKILEAFKTSKTVNTVFLSKVG 580

Query: 381 DEGIDVPDASVGIIISG-TGSPRELVQRLGRILRP--------APGKE--RAILYELITP 429
           D  ID+P+A+V I IS   GS R+  QRLGRILR         A GKE   A  Y L++ 
Sbjct: 581 DNSIDIPEANVIIQISSHAGSRRQEAQRLGRILRAKGKLEDRMAGGKEEYNAFFYSLVST 640

Query: 430 GTTEVRISSRR 440
            T E+  S++R
Sbjct: 641 DTQEMYYSTKR 651


>dbj|BAB08508.1| (AB006707) DNA excision repair cross-complementing protein
           [Arabidopsis thaliana]
           Length = 754
           
 Score =  127 bits (315), Expect = 3e-28
 Identities = 125/431 (29%), Positives = 196/431 (45%), Gaps = 80/431 (18%)

Query: 52  EDYVLENALPSRVYDDVEFEL------RDYQEEAVERWM---REKRGVIVLPTGAGKTIV 102
           E+Y   N     V  D++ EL      R YQE+++ +     R + G+IVLP GAGK++V
Sbjct: 247 EEYDFRN---DNVNPDLDMELKPHAQPRPYQEKSLSKMFGNGRARSGIIVLPCGAGKSLV 303

Query: 103 AMEIIKRLSLSTLVIVPTLALLEQWKERLEIFGDVGE-----FSGRKKEL----KPITVT 153
            +    R+  S L +      ++QW  + +++  + +     F+   KE       + VT
Sbjct: 304 GVSAAARIKKSCLCLATNAVSVDQWAYQFKLWSTIKDDQICRFTSDSKERFRGNAGVVVT 363

Query: 154 TY-----------DSAYINAEFLGDKFFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTA 202
           TY           ++  I  E    ++ LL+ DE H +P+  +R +  ++ +  +LGLTA
Sbjct: 364 TYNMIAFGGKRSEEAEKIIEEMRNREWGLLLMDEVHVVPAHMFRKVISITKSHCKLGLTA 423

Query: 203 FPERADNLHDLLPDLIGPIVYKKAPRELM-GTYLAPYELVRVKVPLSREERAEYLKHYKV 261
              R D     L  LIGP +Y+    +L+ G ++A  +   V  P+++E  AEYLK    
Sbjct: 424 TLVREDEKITDLNFLIGPKLYEANWLDLVKGGFIANVQCAEVWCPMTKEFFAEYLKK--- 480

Query: 262 FKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKIALGSKAKIEELRKILE 321
                          E+ +K      ++   F+A                  E L +  E
Sbjct: 481 ---------------ENSKKKQALYVMNPNKFRA-----------------CEFLIRFHE 508

Query: 322 RHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERVEILRKFREGKYM-AVVSSQVL 380
           + RG+KII+       + E + K   P I   TS  ER +IL  F+  K +  V  S+V 
Sbjct: 509 QQRGDKIIVFADNLFALTEYAMKLRKPMIYGATSHIERTKILEAFKTSKTVNTVFLSKVG 568

Query: 381 DEGIDVPDASVGIIISG-TGSPRELVQRLGRILRP--------APGKE--RAILYELITP 429
           D  ID+P+A+V I IS   GS R+  QRLGRILR         A GKE   A  Y L++ 
Sbjct: 569 DNSIDIPEANVIIQISSHAGSRRQEAQRLGRILRAKGKLEDRMAGGKEEYNAFFYSLVST 628

Query: 430 GTTEVRISSRR 440
            T E+  S++R
Sbjct: 629 DTQEMYYSTKR 639


>pir||A75209 DNA repair protein rad25 PAB0128 - Pyrococcus abyssi (strain Orsay)
           >gi|5457629|emb|CAB49120.1| (AJ248283) DNA repair
           protein RAD25 [Pyrococcus abyssi]
           Length = 446
           
 Score =  124 bits (309), Expect = 2e-27
 Identities = 109/421 (25%), Positives = 199/421 (46%), Gaps = 59/421 (14%)

Query: 20  YARWDERCRCYRALAYKYR-----DIVEFLESEGIEF---EDYVLENALPSRVYDDVEFE 71
           + RWD+    Y      +       + +FL S+G      ++ V++    +  +++  ++
Sbjct: 36  FGRWDKAESLYDPYTNTFPVGLLPRVKKFLNSKGYRVKVKDERVIDGVKINSTWNE-NYK 94

Query: 72  LRDYQEEAVERWMREKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWKERL 131
           LR YQ++AV+  ++EK GV+ LP G+GKT+V + II  +  S L+IV T  LL QW +++
Sbjct: 95  LRKYQKKAVKLAIKEKMGVLALPVGSGKTVVGLRIIHEIGRSALIIVHTKELLYQWADKV 154

Query: 132 -EIFG-DVGEFSGRKKELKPITVTTYDSAYI-NAEFLGDKFFLLIFDECHHL-PSEAYRN 187
            EI G + G     K     ITV    +      + L +K+ +++FDECH    +E +  
Sbjct: 155 KEILGIEPGIIGDNKWSEGDITVAMIQTLLSRGTDKLQNKYAIVMFDECHRTSAAEKFYE 214

Query: 188 IAQMSAAPYRLGLTAFPERADNLHDL-LPDLIGPIVYKKAPRELMGT-YLAPYELVRVKV 245
           +       YR GL+A P R     ++ +  ++GPI+Y+    +L+   +LA         
Sbjct: 215 VGISLPQVYRFGLSATPWRRLRGEEMKIEGVVGPIIYEVKAEDLINEGFLAK-------- 266

Query: 246 PLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKI 305
                        ++V +       L  K  E +++ +M     NKA      +E+A ++
Sbjct: 267 -----------PKFEVIEYNSKMPALADKYKELYEEAIMENEERNKAI-----VEKAIEL 310

Query: 306 ALGSKAKIEELRKILERHRGEKIIISTR---YNELVYEISRKFLIPAITHKTSKEERVEI 362
           A                ++G +++I  +   + E++ ++ ++  + A    +    R EI
Sbjct: 311 A----------------NQGHRVLIDVKRIDHGEILVKMLKERGVNAEFLSSQSPNRWEI 354

Query: 363 LRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKERAI 422
           L KF+ G+   +VS+ +L EG+D+P+ S  I+  G  S    +Q +GR LRP  G E  I
Sbjct: 355 LEKFKNGEIPVLVST-LLKEGVDIPEISAIILAGGGKSDVMTIQTIGRALRPKAGGEAVI 413

Query: 423 L 423
           +
Sbjct: 414 V 414


>pir||S71206 DNA excision repair cross-complementing protein ERCC3 - Arabidopsis
           thaliana
           Length = 757
           
 Score =  124 bits (308), Expect = 2e-27
 Identities = 126/433 (29%), Positives = 195/433 (44%), Gaps = 82/433 (18%)

Query: 52  EDYVLENALPSRVYDDVEFEL------RDYQEEAVERWM-----REKRGVIVLPTGAGKT 100
           E+Y   N     V  D++ EL      R YQE+++         R + G+IVLP GAGK+
Sbjct: 247 EEYDFRN---DNVNPDLDMELKPHAQPRPYQEKSLRASKMFGNGRARSGIIVLPCGAGKS 303

Query: 101 IVAMEIIKRLSLSTLVIVPTLALLEQWKERLEIFGDVGE-----FSGRKKEL----KPIT 151
           +V +    R+  S L +      ++QW  + +++  + +     F+   KE       + 
Sbjct: 304 LVGVSAAARIKKSCLCLATNAVSVDQWAFQFKLWSTIRDDQICRFTSDSKERFRGNAGVV 363

Query: 152 VTTY-----------DSAYINAEFLGDKFFLLIFDECHHLPSEAYRNIAQMSAAPYRLGL 200
           VTTY           +S  I  E    ++ LL+ DE H +P+  +R +  ++ +  +LGL
Sbjct: 364 VTTYNMVAFGGKRSEESEKIIEEMRNREWGLLLMDEVHVVPAHMFRKVISITKSHCKLGL 423

Query: 201 TAFPERADNLHDLLPDLIGPIVYKKAPRELM-GTYLAPYELVRVKVPLSREERAEYLKHY 259
           TA   R D     L  LIGP +Y+    +L+ G ++A  +   V  P+++E  AEYLK  
Sbjct: 424 TATLVREDERITDLNFLIGPKLYEANWLDLVKGGFIANVQCAEVWCPMTKEFFAEYLKK- 482

Query: 260 KVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKIALGSKAKIEELRKI 319
                            E+ +K      ++   F+A                  E L + 
Sbjct: 483 -----------------ENSKKKQALYVMNPNKFRA-----------------CEFLIRF 508

Query: 320 LERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERVEILRKFREGKYM-AVVSSQ 378
            E+ RG+KII+       + E + K   P I   TS  ER +IL  F+  K +  V  S+
Sbjct: 509 HEQQRGDKIIVFADNLFALTEYAMKLRKPMIYGATSHIERTKILEAFKTSKDVNTVFLSK 568

Query: 379 VLDEGIDVPDASVGIIISG-TGSPRELVQRLGRILRP--------APGKE--RAILYELI 427
           V D  ID+P+A+V I IS   GS R+  QRLGRILR         A GKE   A  Y L+
Sbjct: 569 VGDNSIDIPEANVIIQISSHAGSRRQEAQRLGRILRAKGKLEDRMAGGKEEYNAFFYSLV 628

Query: 428 TPGTTEVRISSRR 440
           +  T E+  S++R
Sbjct: 629 STDTQEMYYSTKR 641


>gb|AAG19725.1| (AE005058) putative DNA helicase; Rhl [Halobacterium sp. NRC-1]
           Length = 324
           
 Score =  119 bits (295), Expect = 7e-26
 Identities = 100/360 (27%), Positives = 168/360 (45%), Gaps = 56/360 (15%)

Query: 104 MEIIKRLSLSTLVIVPTLALLEQWKERL----EIFGD-VGEFSGRKKELKPITVTTYDSA 158
           M  ++ +   TLV+VP+  L  QW+E L     + GD +GE+ G +K ++P+T+ TY +A
Sbjct: 1   MGALESVGGETLVLVPSRELATQWREELLANTSLTGDQIGEYHGGEKRVRPVTIATYQTA 60

Query: 159 YINAE---FLGDKFFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLP 215
            ++     F   ++ L+++DE HH+P+E  R  A +  + +RLGLTA P R D+    + 
Sbjct: 61  GMDRHRHVFDDREWGLIVYDEVHHIPAEVARRSASLQ-SKHRLGLTATPVREDDKEADIY 119

Query: 216 DLIGPIVYKKAPRELMGTYLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKS 275
            L+G  +           ++A  E V ++    R++   Y         Y + SG     
Sbjct: 120 TLVGRPIGTDWDALFDAGFVAEPE-VEIRYVPWRDDDDRY--------EYAAASG----- 165

Query: 276 LEDFQKIVMRTGVDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYN 335
                                      R++A  + AK  E+  ++++H   + ++   Y 
Sbjct: 166 ------------------------HTRRRLAAENPAKEAEIEHLVDQHGDTQALVFVDYL 201

Query: 336 ELVYEISRKFLIPAITHKTSKEERVEILRKFREGKYMAVVSSQVLDEGIDVPDASVGIII 395
                I+ +   P +  +T    R     +FR G   A+V S++ DEGID+PDA   ++ 
Sbjct: 202 SQGERIAERLDAPFVNGETPHSRRETHFDQFRTGALDALVVSRIGDEGIDLPDAEFAVVA 261

Query: 396 SGT-GSPRELVQRLGRILRPAPGKERAILYELITPGTTE---VRISSRRLS--GIKKLES 449
           SG  GS R+  QR GR +RP     +++L+ L T GT E    R   R LS  G++  ES
Sbjct: 262 SGLGGSRRQGAQRAGRTMRPG---SQSLLFVLATRGTEEEDHARSRMRHLSTKGVRVTES 318


>gb|AAB62732.1| (U77065) RepB [Dictyostelium discoideum]
           Length = 800
           
 Score =  116 bits (288), Expect = 5e-25
 Identities = 114/398 (28%), Positives = 185/398 (45%), Gaps = 65/398 (16%)

Query: 72  LRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWK 128
           +R YQE+++ +     R + G+IVLP GAGK++  +     +  S LV+  +   +EQWK
Sbjct: 318 IRPYQEKSLSKMFGNGRARSGIIVLPCGAGKSLSGITAACTVKKSILVLCTSAVSVEQWK 377

Query: 129 ERLEIFGDVGE-----FSGRKKE----LKPITVTTY-----------DSAYINAEFLGDK 168
            + +++ ++ E     F+   KE    +  +T+TTY           +S  I  E    +
Sbjct: 378 YQFKLWSNIEERQISKFTSDNKEKISNVAGVTITTYTMVAFGGRRSAESLKIMNEITNRE 437

Query: 169 FFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPR 228
           + L++ DE H +P+  +R +  ++ A  +LGLTA   R D     L  LIGP +Y+    
Sbjct: 438 WGLVLLDEVHVVPAAMFRKVLTVTKAHCKLGLTATLLREDEKIQDLNFLIGPKLYEANWL 497

Query: 229 ELM-GTYLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTG 287
           +L    +LA      V  P++ E   EYL         +++S          +K ++ T 
Sbjct: 498 DLQKAGFLANVSCSEVWCPMTAEFYKEYL---------INDS--------QGKKKLLYTM 540

Query: 288 VDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLI 347
             NK F+A   L                        RG+KII+ +     + + ++    
Sbjct: 541 NPNK-FRACEYLIR------------------FHEQRGDKIIVFSDNVYALQKYAKGLGR 581

Query: 348 PAITHKTSKEERVEILRKFR-EGKYMAVVSSQVLDEGIDVPDASVGIIISG-TGSPRELV 405
             I   TS  ER+ IL KF+ +     +  S+V D  ID+P+A+V I +S   GS R+  
Sbjct: 582 YFIYGPTSGHERMSILSKFQHDPTVRTIFISKVGDTSIDIPEATVIIQVSSHYGSRRQEA 641

Query: 406 QRLGRILRPAP---GKERAILYELITPGTTEVRISSRR 440
           QRLGRILRP P   G   A  Y L++  T E+  S++R
Sbjct: 642 QRLGRILRPKPKSDGLYNAFFYSLVSKDTQEMYYSTKR 679


>gi|4557563 excision repair cross-complementing rodent repair deficiency,
           complementation group 3 (xeroderma pigmentosum group B
           complementing); Excision-repair cross-complementing
           rodent repair deficiency,; excision repair
           cross-complementing rodent repair defici>
           >gi|119541|sp|P19447|XPB_HUMAN DNA-REPAIR PROTEIN
           COMPLEMENTING XP-B CELLS (XERODERMA PIGMENTOSUM GROUP B
           COMPLEMENTING PROTEIN) (DNA EXCISION REPAIR PROTEIN
           ERCC-3) (BASAL TRANSCRIPTION FACTOR 2 89 KDA SUBUNIT)
           (BTF2-P89) (TFIIH 89 KDA SUBUNIT) >gi|105955|pir||A35661
           DNA excision repair cross-complementing protein ERCC3 -
           human >gi|182179|gb|AAA52396.1| (M31899) DNA repair
           helicase [Homo sapiens]
           Length = 782
           
 Score =  113 bits (279), Expect = 6e-24
 Identities = 110/399 (27%), Positives = 185/399 (45%), Gaps = 68/399 (17%)

Query: 72  LRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWK 128
           LR YQE+++ +     R + GVIVLP GAGK++V +     +    LV+  +   +EQWK
Sbjct: 316 LRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWK 375

Query: 129 ERLEIFGDVGE-----FSGRKKELKPI---------------TVTTYDSAYINAEFLGDK 168
            + +++  + +     F+   K+ KPI               T  ++++  +       +
Sbjct: 376 AQFKMWSTIDDSQICRFTSDAKD-KPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQE 434

Query: 169 FFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPR 228
           + L+I DE H +P++ +R +  +  A  +LGLTA   R D+    L  LIGP +Y+    
Sbjct: 435 WGLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWM 494

Query: 229 ELMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTG 287
           EL    Y+A  +   V  P+S E   EY+                  +++  ++I++ T 
Sbjct: 495 ELQNNGYIAKVQCAEVWCPMSPEFYREYV------------------AIKTKKRILLYTM 536

Query: 288 VDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLI 347
             NK F+A + L +                      R +KII+       + E + +   
Sbjct: 537 NPNK-FRACQFLIK------------------FHERRNDKIIVFADNVFALKEYAIRLNK 577

Query: 348 PAITHKTSKEERVEILRKFREG-KYMAVVSSQVLDEGIDVPDASVGIIISG-TGSPRELV 405
           P I   TS+ ER++IL+ F+   K   +  S+V D   D+P+A+V I IS   GS R+  
Sbjct: 578 PYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEA 637

Query: 406 QRLGRILRPAPG----KERAILYELITPGTTEVRISSRR 440
           QRLGR+LR   G    +  A  Y L++  T E+  S++R
Sbjct: 638 QRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKR 676


>sp|P49135|XPB_MOUSE DNA-REPAIR PROTEIN COMPLEMENTING XP-B CELLS HOMOLOG (XERODERMA
           PIGMENTOSUM GROUP B COMPLEMENTING PROTEIN HOMOLOG) (DNA
           EXCISION REPAIR PROTEIN ERCC-3) (BASAL TRANSCRIPTION
           FACTOR 2 89 KD SUBUNIT) (BTF2-P89) (TFIIH 89 KD SUBUNIT)
           >gi|477426|pir||A48994 DNA excision repair
           cross-complementing protein ERCC3 - mouse
           >gi|240583|gb|AAB20614.1| (S71186) XPBC/ERCC-3=DNA
           repair gene [mice, Peptide, 783 aa] [Mus sp.]
           Length = 783
           
 Score =  112 bits (278), Expect = 7e-24
 Identities = 110/399 (27%), Positives = 184/399 (45%), Gaps = 68/399 (17%)

Query: 72  LRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWK 128
           LR YQE+++ +     R + GVIVLP GAGK++V +     +    LV+  +   +EQWK
Sbjct: 317 LRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWK 376

Query: 129 ERLEIFGDVGE-----FSGRKKELKPI---------------TVTTYDSAYINAEFLGDK 168
            + +++  + +     F+   K+ KPI               T  ++++  +       +
Sbjct: 377 AQFKMWSTIDDSQICRFTSDAKD-KPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQE 435

Query: 169 FFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPR 228
           + L+I DE H +P+  +R +  +  A  +LGLTA   R D+    L  LIGP +Y+    
Sbjct: 436 WGLMILDEVHTIPARMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWM 495

Query: 229 ELMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTG 287
           EL    Y+A  +   V  P+S E   EY+                  +++  ++I++ T 
Sbjct: 496 ELQNNGYIAKVQCAEVWCPMSPEFYREYV------------------AIKTKKRILLYTM 537

Query: 288 VDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLI 347
             NK F+A + L +                      R +KII+       + E + +   
Sbjct: 538 NPNK-FRACQFLIK------------------FHERRNDKIIVFADNVFALKEYAIRLNK 578

Query: 348 PAITHKTSKEERVEILRKFREG-KYMAVVSSQVLDEGIDVPDASVGIIISG-TGSPRELV 405
           P I   TS+ ER++IL+ F+   K   +  S+V D   D+P+A+V I IS   GS R+  
Sbjct: 579 PYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEA 638

Query: 406 QRLGRILRPAPG----KERAILYELITPGTTEVRISSRR 440
           QRLGR+LR   G    +  A  Y L++  T E+  S++R
Sbjct: 639 QRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKR 677


>pir||T31655 DNA excision repair cross-complementing protein - sea squirt (Ciona
           intestinalis) >gi|1764011|emb|CAB06045.1| (Z83760)
           COS41.1 [Ciona intestinalis]
           Length = 793
           
 Score =  110 bits (272), Expect = 4e-23
 Identities = 115/443 (25%), Positives = 199/443 (43%), Gaps = 80/443 (18%)

Query: 38  RDIVEFLESEGIEFE-----DYVLENALPSRVYDDVEFEL------RDYQEEAVERWM-- 84
           +++VE L+   IE E     +Y   N     +  D++ +L      R YQE+++ +    
Sbjct: 286 QEMVETLQKRCIELEYPLLAEYDFRN---DTINKDLKIDLKPTTVLRPYQEKSLRKMFGN 342

Query: 85  -REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWKERLEIFGDVGE---- 139
            R + GVIVLP GAGKT+V +     +    +V+  +   +EQW+ + +++    +    
Sbjct: 343 GRARSGVIVLPCGAGKTLVGVTAACTVRKRCMVLCTSGVAVEQWRSQFKMWSTADDSMIC 402

Query: 140 -FSGRKKELK---PITVTTY-----------DSAYINAEFLGDKFFLLIFDECHHLPSEA 184
            F+   K+      I ++TY           +S  +       ++ L++ DE H +P++ 
Sbjct: 403 RFTSDAKDRPHGCSIAISTYSMMGHSMKRSYESEKVMEWIRSQEWGLIVLDEVHTIPAKQ 462

Query: 185 YRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELM-GTYLAPYELVRV 243
           +R +  +  +  +LGLTA   R D+    L  LIGP +Y+    EL  G ++A  +   V
Sbjct: 463 FRRVLTVVQSHCKLGLTATLVREDDKISDLNFLIGPKLYEANWMELQNGGFIARVQCAEV 522

Query: 244 KVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEAR 303
             P++ E   EYL                  S+   +++++     NK F+A + L    
Sbjct: 523 WCPMTPEFYREYL------------------SIRSRKRLLLYVMNPNK-FRACQFLVR-- 561

Query: 304 KIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERVEIL 363
                               R +KI++ +     + E + +   P I   T++ ER++IL
Sbjct: 562 ----------------FHERRNDKIVVFSDNVFALKEYAVRMGKPYIYGPTTQGERLQIL 605

Query: 364 RKF-REGKYMAVVSSQVLDEGIDVPDASVGIIISG-TGSPRELVQRLGRILRPAPG---- 417
           + F    K   +  S+V D  ID+P A+V I +S   GS R+  QRLGRILR   G    
Sbjct: 606 QNFIHNPKVNTIFISKVGDNSIDLPAANVLIQVSSHGGSRRQEAQRLGRILRAKKGSLAE 665

Query: 418 KERAILYELITPGTTEVRISSRR 440
           +  A  Y L++  T EV  S++R
Sbjct: 666 EYNAFFYSLVSQDTVEVAYSTKR 688


>sp|Q02870|XPB_DROME DNA EXCISION REPAIR PROTEIN HAYWIRE (ERCC-3 HOMOLOG PROTEIN)
           >gi|283659|pir||S26719 ERCC3 protein - fruit fly
           (Drosophila melanogaster) >gi|11079|emb|CAA48386.1|
           (X68309) ERCC3 [Drosophila melanogaster]
           Length = 802
           
 Score =  109 bits (270), Expect = 6e-23
 Identities = 112/401 (27%), Positives = 183/401 (44%), Gaps = 72/401 (17%)

Query: 72  LRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWK 128
           LR YQE+++ +     R + GVIVLP GAGK++V +     +    LV+  +   +EQWK
Sbjct: 336 LRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTACCTVRKRALVLCNSGVSVEQWK 395

Query: 129 ERLEIFGDVGE-----FSGRKKELKP----ITVTTYD----------SAYINAEFLGD-K 168
           ++ +++    +     F+   K+ KP    I VTTY            A     +L + +
Sbjct: 396 QQFKMWSTADDSMICRFTSEAKD-KPMGCGILVTTYSMITHTQKRSWEAEQTMRWLQEQE 454

Query: 169 FFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPR 228
           + +++ DE H +P++ +R +  +  +  +LGLTA   R D+    L  LIGP +Y+    
Sbjct: 455 WGIMVLDEVHTIPAKMFRRVLTIVQSHCKLGLTATLLREDDKIADLNFLIGPKLYEANWL 514

Query: 229 ELMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTG 287
           EL    Y+A  +   V  P+S E   EYL   K  K+ L                     
Sbjct: 515 ELQKKGYIARVQCAEVWCPMSPEFYREYLT-TKTSKKML--------------------- 552

Query: 288 VDNKAFKALRALEEARKIALGSKAKIEELRKILERH--RGEKIIISTRYNELVYEISRKF 345
                            + + + +K    + +++ H  RG+K I+ +     +   + K 
Sbjct: 553 -----------------LYVMNPSKFRSCQFLIKYHEQRGDKTIVFSDNVFALKHYAIKM 595

Query: 346 LIPAITHKTSKEERVEILRKFR-EGKYMAVVSSQVLDEGIDVPDASVGIIISG-TGSPRE 403
             P I   TS+ ER++IL+ F+   K   +  S+V D   D+P+A+V I IS   GS R+
Sbjct: 596 NKPFIYGPTSQNERIQILQNFKFNSKVNTIFVSKVADTSFDLPEANVLIQISSHGGSRRQ 655

Query: 404 LVQRLGRILRPAPG----KERAILYELITPGTTEVRISSRR 440
             QRLGRILR   G    +  A  Y L++  T E+  S +R
Sbjct: 656 EAQRLGRILRAKKGAIAEEYNAFFYTLVSQDTMEMSYSRKR 696


>gb|AAF50150.1| (AE003547) hay gene product [Drosophila melanogaster]
           Length = 798
           
 Score =  109 bits (270), Expect = 6e-23
 Identities = 112/401 (27%), Positives = 183/401 (44%), Gaps = 72/401 (17%)

Query: 72  LRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWK 128
           LR YQE+++ +     R + GVIVLP GAGK++V +     +    LV+  +   +EQWK
Sbjct: 332 LRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTACCTVRKRALVLCNSGVSVEQWK 391

Query: 129 ERLEIFGDVGE-----FSGRKKELKP----ITVTTYD----------SAYINAEFLGD-K 168
           ++ +++    +     F+   K+ KP    I VTTY            A     +L + +
Sbjct: 392 QQFKMWSTADDSMICRFTSEAKD-KPMGCGILVTTYSMITHTQKRSWEAEQTMRWLQEQE 450

Query: 169 FFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPR 228
           + +++ DE H +P++ +R +  +  +  +LGLTA   R D+    L  LIGP +Y+    
Sbjct: 451 WGIMVLDEVHTIPAKMFRRVLTIVQSHCKLGLTATLLREDDKIADLNFLIGPKLYEANWL 510

Query: 229 ELMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTG 287
           EL    Y+A  +   V  P+S E   EYL   K  K+ L                     
Sbjct: 511 ELQKKGYIARVQCAEVWCPMSPEFYREYLT-TKTSKKML--------------------- 548

Query: 288 VDNKAFKALRALEEARKIALGSKAKIEELRKILERH--RGEKIIISTRYNELVYEISRKF 345
                            + + + +K    + +++ H  RG+K I+ +     +   + K 
Sbjct: 549 -----------------LYVMNPSKFRSCQFLIKYHEQRGDKTIVFSDNVFALKHYAIKM 591

Query: 346 LIPAITHKTSKEERVEILRKFR-EGKYMAVVSSQVLDEGIDVPDASVGIIISG-TGSPRE 403
             P I   TS+ ER++IL+ F+   K   +  S+V D   D+P+A+V I IS   GS R+
Sbjct: 592 NKPFIYGPTSQNERIQILQNFKFNSKVNTIFVSKVADTSFDLPEANVLIQISSHGGSRRQ 651

Query: 404 LVQRLGRILRPAPG----KERAILYELITPGTTEVRISSRR 440
             QRLGRILR   G    +  A  Y L++  T E+  S +R
Sbjct: 652 EAQRLGRILRAKKGAIAEEYNAFFYTLVSQDTMEMSYSRKR 692


>pir||A44223 DNA excision repair cross-complementing protein ERCC3 - fruit fly
           (Drosophila melanogaster)
           Length = 802
           
 Score =  109 bits (269), Expect = 8e-23
 Identities = 111/399 (27%), Positives = 177/399 (43%), Gaps = 69/399 (17%)

Query: 72  LRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWK 128
           LR YQE+++ +     R + GVIVLP GAGK++V +     +    LV+  +   +EQWK
Sbjct: 337 LRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTACCTVRKRALVLCNSGVSVEQWK 396

Query: 129 ERLEIFGDVGE-----FSGRKKELKP----ITVTTYD----------SAYINAEFLGD-K 168
           ++ +++    +     F+   K+ KP    I VTTY            A     +L + +
Sbjct: 397 QQFKMWSTADDSMICRFTSEAKD-KPMGCGILVTTYSMITHTQKRSWEAEQTMRWLQEQE 455

Query: 169 FFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPR 228
           + +++ DE H +P++ +R +  +  +  +LGLTA   R D+    L  LIGP +Y+    
Sbjct: 456 WGIMVLDEVHTIPAKMFRRVLTIVQSHCKLGLTATLLREDDKIADLNFLIGPKLYEANWL 515

Query: 229 ELMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTG 287
           EL    Y+A  +   V  P+S E   EYL      K  L  +  + +S +   K      
Sbjct: 516 ELQKKGYIARVQCAEVWCPMSPEFYREYLTTKTSKKMLLYVNPSKFRSCQFLIK------ 569

Query: 288 VDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLI 347
                                               RG+K I+ +     +   + K   
Sbjct: 570 --------------------------------YHEQRGDKTIVFSDNVFALKHYAIKMNK 597

Query: 348 PAITHKTSKEERVEILRKFR-EGKYMAVVSSQVLDEGIDVPDASVGIIISG-TGSPRELV 405
           P I   TS+ ER++IL+ F+   K   +  S+V D   D+P+A+V I IS   GS R+  
Sbjct: 598 PFIYGPTSQNERIQILQNFKFNSKVNTIFVSKVADTSFDLPEANVLIQISSHGGSRRQEA 657

Query: 406 QRLGRILRPAPG----KERAILYELITPGTTEVRISSRR 440
           QRLGRILR   G    +  A  Y L++  T E+  S +R
Sbjct: 658 QRLGRILRAKKGAIAEEYNAFFYTLVSQDTMEMSYSRKR 696


>emb|CAA76655.1| (Y17148) XPB protein [Geodia cydonium]
           Length = 810
           
 Score =  109 bits (269), Expect = 8e-23
 Identities = 108/403 (26%), Positives = 190/403 (46%), Gaps = 75/403 (18%)

Query: 72  LRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWK 128
           LR YQE+++ +     R + GVIVLP GAGKT+V +     +    LV+  +   +EQW+
Sbjct: 335 LRPYQEKSLRKMFGNGRARSGVIVLPCGAGKTLVGVTAACTVRKRCLVLCTSAVAVEQWR 394

Query: 129 ERLEIFGDVGE-----FSGRKKELKP-----ITVTTY-----------DSAYINAEFLGD 167
            + +++  + E     F+   K+ KP     + ++TY           DS  +       
Sbjct: 395 SQFKLWSTIDERLVCRFTSDAKD-KPSPNTAVAISTYAMVAYTQKRAWDSQQMMNFLQQQ 453

Query: 168 KFFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAP 227
           ++ L+I DE   +P++ +R    +  A  +LGLTA   R D+    L  LIGP +Y+   
Sbjct: 454 EWGLMILDEVQTIPADKFRRTLAVVQAHTKLGLTATLVREDDKIQDLNFLIGPKLYEANW 513

Query: 228 RELMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRT 286
            EL    ++A  +   V  P++ E  +EYLK                  ++  +K ++  
Sbjct: 514 MELQNNGFIAKVQCAEVWCPMTPEFYSEYLK------------------IKTRRKKLLYV 555

Query: 287 GVDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEI---SR 343
              NK F+A + L +  +                   R +KIII   ++++V+ +   ++
Sbjct: 556 MNPNK-FRACQFLMKHHE------------------QRNDKIII---FSDVVFSLRTYAK 593

Query: 344 KFLIPAITHKTSKEERVEILRKFREGKYM-AVVSSQVLDEGIDVPDASVGIIISG-TGSP 401
           +   P I  +T+++ER+++L+ F+    +  ++ S+V D   D+PDA+V   IS   GS 
Sbjct: 594 RLNKPFIDGQTNQQERMKVLQNFKHNPLVNTILISKVGDNSFDLPDANVLWKISAHGGSR 653

Query: 402 RELVQRLGRILR----PAPGKERAILYELITPGTTEVRISSRR 440
           R+  QRLG ILR        +  A  Y L++  T E+  S++R
Sbjct: 654 RQEAQRLGGILRAKKDSVSEEYNAFFYSLVSQDTEEMHFSTKR 696


>gb|AAA34942.1| (L01414) DNA helicase [Saccharomyces cerevisiae]
           Length = 843
           
 Score =  108 bits (267), Expect = 1e-22
 Identities = 108/404 (26%), Positives = 181/404 (44%), Gaps = 76/404 (18%)

Query: 71  ELRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQW 127
           ++R YQE+++ +     R + G+IVLP GAGKT+V +     +  S +V+  +   + QW
Sbjct: 361 QIRPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLVGITAACTIKKSVIVLCTSSVSVMQW 420

Query: 128 KERLEIF-----GDVGEFSGRKKEL----KPITVTTY-----------DSAYINAEFLGD 167
           +++   +      +   F+   KE+      + V+TY           DS  +     G 
Sbjct: 421 RQQFLQWCTLQPENCAVFTSDNKEMFQTESGLVVSTYSMVANTRNRSHDSQKVMDFLTGR 480

Query: 168 KFFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAP 227
           ++  +I DE H +P+  +R +    AA  +LGLTA   R D+    L  LIGP +Y+   
Sbjct: 481 EWGFIILDEVHVVPAAMFRRVVSTIAAHAKLGLTATLVREDDKIGDLNFLIGPKLYEANW 540

Query: 228 REL-MGTYLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRT 286
            EL    ++A  +   V  P++ E   EYL+                             
Sbjct: 541 MELSQKGHIANVQCAEVWCPMTAEFYQEYLR----------------------------- 571

Query: 287 GVDNKAFKALRALEEARK---IALGSKAKIEELRKILERH--RGEKIIISTRYNELVYEI 341
                        E ARK   + + +  K +  + +++ H  RG+KII+ +     + E 
Sbjct: 572 -------------ETARKRMLLYIMNPTKFQACQFLIQYHERRGDKIIVFSDNVYALQEY 618

Query: 342 SRKFLIPAITHKTSKEERVEILRKFR-EGKYMAVVSSQVLDEGIDVPDASVGIIISG-TG 399
           + K   P I   T ++ER+ IL+ F+   +   +  S+V D  ID+P+A+  I IS   G
Sbjct: 619 ALKMGKPFIYGSTPQQERMNILQNFQYNDQINTIFLSKVGDTSIDLPEATCLIQISSHYG 678

Query: 400 SPRELVQRLGRILRPAPGKE---RAILYELITPGTTEVRISSRR 440
           S R+  QRLGRILR     +    A  Y L++  T E+  S++R
Sbjct: 679 SRRQEAQRLGRILRAKRRNDEGFNAFFYSLVSKDTQEMYYSTKR 722


>gi|6322048 DNA helicase homolog; homolog of human XPBC, ERCC3; Ssl2p
           [Saccharomyces cerevisiae]
           >gi|267033|sp|Q00578|RA25_YEAST DNA REPAIR HELICASE
           RAD25 >gi|320659|pir||S31272 DNA excision repair
           cross-complementing protein ERCC3 [validated] - yeast
           (Saccharomyces cerevisiae) >gi|172724|gb|AAA35102.1|
           (M94176) encodes human ERCC-3 homologue [Saccharomyces
           cerevisiae] >gi|557780|emb|CAA86135.1| (Z38059) DNA
           repair helicase [Saccharomyces cerevisiae]
           Length = 843
           
 Score =  108 bits (267), Expect = 1e-22
 Identities = 108/404 (26%), Positives = 181/404 (44%), Gaps = 76/404 (18%)

Query: 71  ELRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQW 127
           ++R YQE+++ +     R + G+IVLP GAGKT+V +     +  S +V+  +   + QW
Sbjct: 361 QIRPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLVGITAACTIKKSVIVLCTSSVSVMQW 420

Query: 128 KERLEIF-----GDVGEFSGRKKEL----KPITVTTY-----------DSAYINAEFLGD 167
           +++   +      +   F+   KE+      + V+TY           DS  +     G 
Sbjct: 421 RQQFLQWCTLQPENCAVFTSDNKEMFQTESGLVVSTYSMVANTRNRSHDSQKVMDFLTGR 480

Query: 168 KFFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAP 227
           ++  +I DE H +P+  +R +    AA  +LGLTA   R D+    L  LIGP +Y+   
Sbjct: 481 EWGFIILDEVHVVPAAMFRRVVSTIAAHAKLGLTATLVREDDKIGDLNFLIGPKLYEANW 540

Query: 228 REL-MGTYLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRT 286
            EL    ++A  +   V  P++ E   EYL+                             
Sbjct: 541 MELSQKGHIANVQCAEVWCPMTAEFYQEYLR----------------------------- 571

Query: 287 GVDNKAFKALRALEEARK---IALGSKAKIEELRKILERH--RGEKIIISTRYNELVYEI 341
                        E ARK   + + +  K +  + +++ H  RG+KII+ +     + E 
Sbjct: 572 -------------ETARKRMLLYIMNPTKFQACQFLIQYHERRGDKIIVFSDNVYALQEY 618

Query: 342 SRKFLIPAITHKTSKEERVEILRKFR-EGKYMAVVSSQVLDEGIDVPDASVGIIISG-TG 399
           + K   P I   T ++ER+ IL+ F+   +   +  S+V D  ID+P+A+  I IS   G
Sbjct: 619 ALKMGKPFIYGSTPQQERMNILQNFQYNDQINTIFLSKVGDTSIDLPEATCLIQISSHYG 678

Query: 400 SPRELVQRLGRILRPAPGKE---RAILYELITPGTTEVRISSRR 440
           S R+  QRLGRILR     +    A  Y L++  T E+  S++R
Sbjct: 679 SRRQEAQRLGRILRAKRRNDEGFNAFFYSLVSKDTQEMYYSTKR 722


>gb|AAA74931.1| (L02965) helicase [Drosophila melanogaster]
           Length = 801
           
 Score =  105 bits (259), Expect = 1e-21
 Identities = 110/399 (27%), Positives = 176/399 (43%), Gaps = 69/399 (17%)

Query: 72  LRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWK 128
           LR YQE+++ +     R + GVIVLP GAGK++V +     +    LV+  +   +EQWK
Sbjct: 336 LRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTACCTVRKRALVLCNSGVSVEQWK 395

Query: 129 ERLEIFGDVGE-----FSGRKKELKP----ITVTTYD----------SAYINAEFLGD-K 168
           ++ +++    +     F+   K+ KP    I VTTY            A     +L + +
Sbjct: 396 QQFKMWSTADDSMICRFTSEAKD-KPMGCGILVTTYSMITHTQKRSWEAEQTMRWLQEQE 454

Query: 169 FFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPR 228
           + +++ DE H +P++ +R +  +  +  +LGLTA   R D+    L  LIGP +Y+    
Sbjct: 455 WGIMVLDEVHTIPAKMFRRVLTIVQSHCKLGLTATLLREDDKIADLNFLIGPKLYEANWL 514

Query: 229 ELMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTG 287
           EL    Y+A  +   V  P+S E   EYL      K  L  +  + +S +   K      
Sbjct: 515 ELQKKGYIARCQCAEVWCPMSPEFYREYLTTKTSKKMLLYVNPSKFRSCQFLIK------ 568

Query: 288 VDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLI 347
                                               RG+K I+ +     +   + K   
Sbjct: 569 --------------------------------YHEQRGDKTIVFSDNVFALKHYAIKMNK 596

Query: 348 PAITHKTSKEERVEILRKFR-EGKYMAVVSSQVLDEGIDVPDASVGIIISG-TGSPRELV 405
           P I   TS+ ER++IL+ F+   K   +  S+V D   D+P+A+V I IS   GS R+  
Sbjct: 597 PFIYGPTSQNERIQILQNFKFNSKVNTIFVSKVADTSFDLPEANVLIQISSHGGSRRQEA 656

Query: 406 QRLGRILRPAPG----KERAILYELITPGTTEVRISSRR 440
           QRL RILR   G    +  A  Y L++  T E+  S +R
Sbjct: 657 QRLVRILRAKKGAIAEEYNAFFYTLVSQDTMEMSYSRKR 695


>pir||T37821 probable dna repair helicase - fission yeast  (Schizosaccharomyces
           pombe) >gi|2370478|emb|CAB11506.1| (Z98849) putative dna
           repair helicase [Schizosaccharomyces pombe]
           Length = 804
           
 Score =  102 bits (253), Expect = 6e-21
 Identities = 108/403 (26%), Positives = 185/403 (45%), Gaps = 74/403 (18%)

Query: 71  ELRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQW 127
           ++R YQE+++ +     R + G+IVLP GAGKT+V +     +  S +V+  +   + QW
Sbjct: 323 QIRPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLVGITAACTIKKSVIVLCTSSVSVMQW 382

Query: 128 KERLEIFGDV-----GEFSGRKKEL----KPITVTTY-----------DSAYINAEFLGD 167
           +++   + ++       F+   KE       + V+TY           DS  +     G 
Sbjct: 383 RQQFLQWSNIKPDHIAVFTADHKERFHSEAGVVVSTYSMVANTRNRSYDSQKMMDFLTGR 442

Query: 168 KFFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAP 227
           ++  ++ DE H +P+  +R +    AA  +LGLTA   R D+  D L  LIGP +Y+   
Sbjct: 443 EWGFILLDEVHVVPAAMFRRVVTTIAAHTKLGLTATLVREDDKIDDLNFLIGPKMYEANW 502

Query: 228 REL-MGTYLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRT 286
            +L    ++A  +   V   ++ E   EYL+                   E+ +K ++  
Sbjct: 503 MDLAQKGHIAKVQCAEVWCAMTTEFYNEYLR-------------------ENSRKRMLLY 543

Query: 287 GVDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFL 346
            ++ K F+A + L +                      RG+KII+   +++ VY + R + 
Sbjct: 544 IMNPKKFQACQFLID------------------YHEKRGDKIIV---FSDNVYAL-RAYA 581

Query: 347 IPA----ITHKTSKEERVEILRKFREGKYM-AVVSSQVLDEGIDVPDASVGIIISG-TGS 400
           I      I   T ++ER+ IL  F+  + +  +  S+V D  ID+P+A+  I IS   GS
Sbjct: 582 IKLGKYFIYGGTPQQERMRILENFQYNELVNTIFLSKVGDTSIDLPEATCLIQISSHYGS 641

Query: 401 PRELVQRLGRILRPAPGKE---RAILYELITPGTTEVRISSRR 440
            R+  QRLGRILR     +    A  Y L++  T E+  SS+R
Sbjct: 642 RRQEAQRLGRILRAKRRNDEGFNAFFYSLVSKDTQEMYYSSKR 684


>gi|11429283 excision repair cross-complementing rodent repair deficiency,
           complementation group 3 (xeroderma pigmentosum group B
           complementing) [Homo sapiens]
           Length = 580
           
 Score = 78.4 bits (190), Expect = 2e-13
 Identities = 81/320 (25%), Positives = 143/320 (44%), Gaps = 62/320 (19%)

Query: 72  LRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWK 128
           LR YQE+++ +     R + GVIVLP GAGK++V +     +    LV+  +   +EQWK
Sbjct: 145 LRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWK 204

Query: 129 ERLEIFGDVGE-----FSGRKKELKPI---------------TVTTYDSAYINAEFLGDK 168
            + +++  + +     F+   K+ KPI               T  ++++  +       +
Sbjct: 205 AQFKMWSTIDDSQICRFTSDAKD-KPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQE 263

Query: 169 FFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPR 228
           + L+I DE H +P++ +R +  +  A  +LGLTA   R D+    L  LIGP +Y+    
Sbjct: 264 WGLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWM 323

Query: 229 ELMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTG 287
           EL    Y+A  +   V  P+S E   EY+                  +++  ++I++ T 
Sbjct: 324 ELQNNGYIAKVQCAEVWCPMSPEFYREYV------------------AIKTKKRILLYTM 365

Query: 288 VDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLI 347
             NK F+A + L +                      R +KII+       + E + +   
Sbjct: 366 NPNK-FRACQFLIK------------------FHERRNDKIIVFADNVFALKEYAIRLNK 406

Query: 348 PAITHKTSKEERVEILRKFR 367
           P I   TS+ ER++IL+ F+
Sbjct: 407 PYIYGPTSQGERMQILQNFK 426


>emb|CAA67095.1| (X98455) SNF [Bacillus cereus]
            Length = 1064
            
 Score = 71.4 bits (172), Expect = 2e-11
 Identities = 106/430 (24%), Positives = 187/430 (42%), Gaps = 79/430 (18%)

Query: 72   LRDYQEEAVERWMREKR-----GVIVLPTGAGKTIVAMEII-------KRLSLSTLVIVP 119
            +R+YQ    E WM+        G++    G GKT+ ++  I       +   L  LV+ P
Sbjct: 613  MREYQVYGFE-WMKTLAYYRFGGILADDMGLGKTLQSIAYIDSVLPEIREKKLPILVVSP 671

Query: 120  TLALLEQWKERLEIFGDV-------GEFSGRKKELKPIT-----VTTYDSAYINAEFLGD 167
            + +L+  W   L+ F          G  + R+K LK +      +T+Y     +      
Sbjct: 672  S-SLVYNWFSELKKFAPHIRAVIADGNQTERRKILKDVAEFDVVITSYPLLRRDVRSYAR 730

Query: 168  KFFLLIFDECHHLPSEAYRNIAQMSA-------APYRLGLTAFP------ERADNLHDLL 214
             F  L  DE     ++A++N    +A       A YR GLT  P      E     H + 
Sbjct: 731  PFHTLFLDE-----AQAFKNPTTQTARAVKTIQAEYRFGLTGTPVENSLEELWSIFHVVF 785

Query: 215  PDLI-GPIVYKKAPRELMGTYLAPYELVRVKVPLSRE--ERAEYLK-------HYKVFKR 264
            P+L+ G   +    RE +   + P+ L R+K  + +E  ++ E+L+         +++  
Sbjct: 786  PELLPGRKEFGDLRREDIANAVKPFVLRRLKEDVLQELPDKIEHLQSSELLPDQKRLYAA 845

Query: 265  YLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKIA----------LGSKAKIE 314
            YL++  LR ++L+   K  +R    NK  + L  L   R+I            GS AK+E
Sbjct: 846  YLAK--LREETLKHLDKDTLRK---NK-IRILAGLTRLRQICNHPALFVDDYKGSSAKLE 899

Query: 315  ELRKILE--RHRGEKIIISTRYNELVYEISRKFLIPAITH-----KTSKEERVEILRKFR 367
            +L  ILE  R  G++I+I +++ +++  I R+    AI +      T  +ERVE+  +F 
Sbjct: 900  QLLDILEECRSTGKRILIFSQFTKMLSIIGRELNRQAIPYFYLDGNTPSQERVELCNRFN 959

Query: 368  EGK-YMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKERAILYEL 426
            EG+  + ++S +    G+++  A   I+     +P    Q   R  R    K    + +L
Sbjct: 960  EGEGDLFLISLKAGGTGLNLTGADTVILYDLWWNPAVEQQAADRAYRMGQ-KNTVQVIKL 1018

Query: 427  ITPGTTEVRI 436
            +  GT E ++
Sbjct: 1019 VAHGTIEEKM 1028


>gi|6320539 Ydr332wp [Saccharomyces cerevisiae] >gi|2131433|pir||S59797
           hypothetical protein YDR332w - yeast (Saccharomyces
           cerevisiae) >gi|914990|gb|AAB64767.1| (U32517) Ydr332wp
           [Saccharomyces cerevisiae]
           Length = 689
           
 Score = 71.4 bits (172), Expect = 2e-11
 Identities = 89/404 (22%), Positives = 180/404 (44%), Gaps = 64/404 (15%)

Query: 72  LRDYQEEAVERWMRE-----KRGVIVLPTGAGKTIVAMEIIKRL----------SLSTLV 116
           LRDYQ++A++  +       KR  + L TG GKT++   +I +L          +  +L+
Sbjct: 33  LRDYQQDAIDACVNSIRQGTKRIGVSLATGGGKTVIFSNLINQLRQNYFKERQGNFKSLI 92

Query: 117 IV-------PTLALLEQWKERLEIFGDVGEFSGRKKELKPITVTTYDSAYINAEFLGDKF 169
           +V          A L++    L++  ++G++    ++   I  +         ++  +  
Sbjct: 93  LVHRRELALQATATLKKIFPDLKVHIEMGKYDCDIEDSDVIVASVQTLIRRLHKYDTNSV 152

Query: 170 FLLIFDECHHLPSEAYRNIA---QMSAAPYRL---GLTAFPERADNLHDLLPDLIGPIVY 223
            L+I DE HH  + +YR+I    + S A  ++   G +A  ERAD     L  ++  IVY
Sbjct: 153 NLIIIDEAHHSVANSYRSILDHFKASTAETKIPVIGFSATFERADKR--ALSMVMDKIVY 210

Query: 224 KKAPRELMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKI 282
            +   E++   +L   +   VK+     +       +++    LS     + + ++  ++
Sbjct: 211 HRGILEMIDDKWLCEAKFTSVKIEADLSDVKSTADDFQLAP--LSS----LMNTKEINEV 264

Query: 283 VMRTGVDNKAFKALRALEEARKIALG-SKAKIEELRKILERHRGEKIIISTRYNELVYEI 341
           +++T +  K  K+L++      +  G  KA ++ L K+ + +      I+T Y       
Sbjct: 265 ILKTYLHKKQEKSLKST-----LLFGVDKAHVQSLHKLFKDNG-----INTDY------- 307

Query: 342 SRKFLIPAITHKTSKEERVEILRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSP 401
                   +T  T + ER  I++KF+ G+   +++  +  EG D+P+    ++   T S 
Sbjct: 308 --------VTSDTKQIERDNIIQKFKNGETEVLMNCGIFTEGTDMPNIDCILLCRPTKSR 359

Query: 402 RELVQRLGRILRPAPGKERAILYELITPGTTEVRISSRRLSGIK 445
             L+Q +GR LR    K+   + + I   +  V +S+  L GI+
Sbjct: 360 SLLIQMIGRGLRLHHSKDHCHIIDFIGASSVGV-VSAPTLLGIR 402


>pir||E71481 probable swf/snf helicase - Chlamydia trachomatis (serotype D, strain
            UW3/Cx) >gi|3329163|gb|AAC68303.1| (AE001341) SWF/SNF
            family helicase [Chlamydia trachomatis]
            Length = 1163
            
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 115/462 (24%), Positives = 197/462 (41%), Gaps = 79/462 (17%)

Query: 64   VYDDVEFELRDYQEEAVERWMREKR-----GVIVLPTGAGKTIVAMEIIKRLSLS----- 113
            V   ++  LR YQ+E V  W+   R     G++    G GKT+  +  + +  L      
Sbjct: 691  VPSQIQATLRGYQKEGVH-WLERLRKMHLNGILADDMGLGKTLQTIIAVTQSRLEKGGGC 749

Query: 114  TLVIVPTLALLEQWKERLEIFGDV-------GEFSGRKKELKP-----ITVTTYDSAYIN 161
            +L+I PT +L+  WKE    F          G  S R+K+L       + +T+Y+    +
Sbjct: 750  SLIICPT-SLVYNWKEEFRKFNPEFKTLVVDGIPSQRRKQLASLEEYDVAITSYNLLQKD 808

Query: 162  AEFLGDKFF-LLIFDECHHLPSEAYRNI--AQMSAAPYRLGLTAFP-----ERADNLHD- 212
             +   D  F  ++ DE HH+ +   RN    +M  A +RL LT  P     E   +L D 
Sbjct: 809  IDIYKDFLFDYVVLDEAHHIKNRTTRNAKSVKMIRACHRLILTGTPIENSLEELWSLFDF 868

Query: 213  LLPDL-------------IGPIVYKKAPR-ELMGTYLAPYELVRVKVPLSRE----ERAE 254
            L+P L             IG  +  KA   E +   +AP+ L R+K  +  +        
Sbjct: 869  LMPGLLSSYDRFVGKYIRIGNYMGNKADNVEALRRKVAPFILRRMKEDVLEDLPPVSEIL 928

Query: 255  YLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKIAL------- 307
            Y  H    +R L +S     + ++  ++V + G +      L  L   ++I         
Sbjct: 929  YHCHLTESQRELYQS-YAASARQELSRLVKQEGFERIHIHVLATLTRLKQICCHPAIFAK 987

Query: 308  -----GSKAKIEELRKILER--HRGEKIIISTRYNELVYEISRKFL----IPAITHKTSK 356
                 G  AK + L  +L      G K ++ ++Y +++  I R+ L    IP +    S 
Sbjct: 988  DTPEPGDSAKYDMLMDLLSSLVDSGHKTVVFSQYTKML-GIIRQDLEAKGIPFVYLDGST 1046

Query: 357  EERVEILRKFRE--GKYMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRP 414
            + R+EI+++F E  G  + +VS +    G+++  A   I      +P    Q   R+ R 
Sbjct: 1047 KNRLEIVQQFNEDPGLLVFLVSLKAGGTGLNLVGADTVIHYDMWWNPAVENQATDRVHR- 1105

Query: 415  APGKERAI-LYELITPGTTEVRISS---RRLSGIKKLESLDD 452
              G+ R++  Y+L+T  T E +I S   R+   +KK+ + DD
Sbjct: 1106 -IGQSRSVSSYKLVTLNTIEEKILSLQNRKKGLVKKVINSDD 1146


>emb|CAB93078.1| (AL357432) putative helicase (fragment) [Streptomyces coelicolor
           A3(2)]
           Length = 135
           
 Score = 69.1 bits (166), Expect = 1e-10
 Identities = 38/114 (33%), Positives = 65/114 (56%), Gaps = 1/114 (0%)

Query: 328 IIISTRYNELVYEISRKFLIPAITHKTSKEERVEILRKFREGKYMAVVSSQVLDEGIDVP 387
           I++  +Y + + E+      P I  +TS  +R ++   FR+G+   +V S+V +  ID+P
Sbjct: 1   ILVIGQYIDQLDELGEHLGAPVIKGETSNAQREKLFESFRQGEISVLVVSKVANFSIDLP 60

Query: 388 DASVGIIISGT-GSPRELVQRLGRILRPAPGKERAILYELITPGTTEVRISSRR 440
           +A+V I +SGT GS +E  QRLGR+LRP     +A  Y ++   T +   ++ R
Sbjct: 61  EATVAIQVSGTFGSRQEEAQRLGRVLRPKADGHQAHFYSVVARDTLDQDFAAHR 114


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.320    0.140    0.395 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 160720877
Number of Sequences: 2977
Number of extensions: 6793279
Number of successful extensions: 22421
Number of sequences better than 1.0e-10: 35
Number of HSP's better than  0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 22315
Number of HSP's gapped (non-prelim): 58
length of query: 453
length of database: 189,106,746
effective HSP length: 57
effective length of query: 396
effective length of database: 154,992,987
effective search space: 61377222852
effective search space used: 61377222852
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 166 (69.1 bits)