BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1312 (RAD25) DE:DNA repair protein RAD25 (453 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||B75006 DNA repair protein rad25 PAB1312 - Pyrococcus abyssi... 897 0.0 pir||C71156 probable helicase protein PH0450 - Pyrococcus horiko... 785 0.0 gi|11497970 DNA repair protein RAD25 [Archaeoglobus fulgidus] >g... 535 e-151 gb|AAK40796.1| DNA repair protein rad25 [Sulfolobus solfataricus] 409 e-113 gi|10803640 ORF H1047 [Halobacterium sp. NRC-1] >gi|7446116|pir|... 367 e-100 emb|CAC12145.1| (AL445066) DNA repair protein RAD25 related prot... 337 2e-91 gb|AAF69763.1| (AF068771) similar to RAD25 [Synechocystis PCC9413] 295 7e-79 pir||B72707 hypothetical protein APE1073 - Aeropyrum pernix (str... 276 4e-73 gb|AAK41233.1| DNA repair protein rad25 [Sulfolobus solfataricus] 273 2e-72 pir||E70815 hypothetical protein Rv0861c - Mycobacterium tubercu... 160 3e-38 pir||F71330 probable DNA repair helicase - syphilis spirochete >... 153 5e-36 pir||H71243 probable helicase protein PH0210 - Pyrococcus horiko... 129 5e-29 gb|AAC49987.1| (U29168) putative DNA repair protein and transcri... 127 3e-28 gb|AAG27465.1|AF308595_1 (AF308595) putative DNA repair protein ... 127 3e-28 dbj|BAB08508.1| (AB006707) DNA excision repair cross-complementi... 127 3e-28 pir||A75209 DNA repair protein rad25 PAB0128 - Pyrococcus abyssi... 124 2e-27 pir||S71206 DNA excision repair cross-complementing protein ERCC... 124 2e-27 gb|AAG19725.1| (AE005058) putative DNA helicase; Rhl [Halobacter... 119 7e-26 gb|AAB62732.1| (U77065) RepB [Dictyostelium discoideum] 116 5e-25 gi|4557563 excision repair cross-complementing rodent repair def... 113 6e-24 sp|P49135|XPB_MOUSE DNA-REPAIR PROTEIN COMPLEMENTING XP-B CELLS ... 112 7e-24 pir||T31655 DNA excision repair cross-complementing protein - se... 110 4e-23 sp|Q02870|XPB_DROME DNA EXCISION REPAIR PROTEIN HAYWIRE (ERCC-3 ... 109 6e-23 gb|AAF50150.1| (AE003547) hay gene product [Drosophila melanogas... 109 6e-23 pir||A44223 DNA excision repair cross-complementing protein ERCC... 109 8e-23 emb|CAA76655.1| (Y17148) XPB protein [Geodia cydonium] 109 8e-23 gb|AAA34942.1| (L01414) DNA helicase [Saccharomyces cerevisiae] 108 1e-22 gi|6322048 DNA helicase homolog; homolog of human XPBC, ERCC3; S... 108 1e-22 gb|AAA74931.1| (L02965) helicase [Drosophila melanogaster] 105 1e-21 pir||T37821 probable dna repair helicase - fission yeast (Schiz... 102 6e-21 gi|11429283 excision repair cross-complementing rodent repair de... 78 2e-13 emb|CAA67095.1| (X98455) SNF [Bacillus cereus] 71 2e-11 gi|6320539 Ydr332wp [Saccharomyces cerevisiae] >gi|2131433|pir||... 71 2e-11 pir||E71481 probable swf/snf helicase - Chlamydia trachomatis (s... 71 3e-11 emb|CAB93078.1| (AL357432) putative helicase (fragment) [Strepto... 69 1e-10 >pir||B75006 DNA repair protein rad25 PAB1312 - Pyrococcus abyssi (strain Orsay) >gi|5459002|emb|CAB50488.1| (AJ248288) DNA repair protein RAD25 [Pyrococcus abyssi] Length = 453 Score = 897 bits (2294), Expect = 0.0 Identities = 453/453 (100%), Positives = 453/453 (100%) Query: 1 MKLYYDRGTIKVIGNSYVPYARWDERCRCYRALAYKYRDIVEFLESEGIEFEDYVLENAL 60 MKLYYDRGTIKVIGNSYVPYARWDERCRCYRALAYKYRDIVEFLESEGIEFEDYVLENAL Sbjct: 1 MKLYYDRGTIKVIGNSYVPYARWDERCRCYRALAYKYRDIVEFLESEGIEFEDYVLENAL 60 Query: 61 PSRVYDDVEFELRDYQEEAVERWMREKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPT 120 PSRVYDDVEFELRDYQEEAVERWMREKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPT Sbjct: 61 PSRVYDDVEFELRDYQEEAVERWMREKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPT 120 Query: 121 LALLEQWKERLEIFGDVGEFSGRKKELKPITVTTYDSAYINAEFLGDKFFLLIFDECHHL 180 LALLEQWKERLEIFGDVGEFSGRKKELKPITVTTYDSAYINAEFLGDKFFLLIFDECHHL Sbjct: 121 LALLEQWKERLEIFGDVGEFSGRKKELKPITVTTYDSAYINAEFLGDKFFLLIFDECHHL 180 Query: 181 PSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELMGTYLAPYEL 240 PSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELMGTYLAPYEL Sbjct: 181 PSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELMGTYLAPYEL 240 Query: 241 VRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALE 300 VRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALE Sbjct: 241 VRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALE 300 Query: 301 EARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERV 360 EARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERV Sbjct: 301 EARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERV 360 Query: 361 EILRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKER 420 EILRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKER Sbjct: 361 EILRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKER 420 Query: 421 AILYELITPGTTEVRISSRRLSGIKKLESLDDL 453 AILYELITPGTTEVRISSRRLSGIKKLESLDDL Sbjct: 421 AILYELITPGTTEVRISSRRLSGIKKLESLDDL 453 >pir||C71156 probable helicase protein PH0450 - Pyrococcus horikoshii >gi|3256853|dbj|BAA29536.1| (AP000002) 449aa long hypothetical protein [Pyrococcus horikoshii] Length = 449 Score = 785 bits (2006), Expect = 0.0 Identities = 378/447 (84%), Positives = 422/447 (93%) Query: 1 MKLYYDRGTIKVIGNSYVPYARWDERCRCYRALAYKYRDIVEFLESEGIEFEDYVLENAL 60 MKLYYDRGTIK+IG+SYVP+ARWDERC CYRALAYKYRDIVEFL+SEG++FED+VL+N + Sbjct: 1 MKLYYDRGTIKIIGSSYVPFARWDERCNCYRALAYKYRDIVEFLKSEGVDFEDHVLDNVI 60 Query: 61 PSRVYDDVEFELRDYQEEAVERWMREKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPT 120 PS Y+DVEFELRDYQ EAVERWM EKRG+IVLPTG+GKTI+AMEI++RLS+STLV+VPT Sbjct: 61 PSPFYEDVEFELRDYQREAVERWMMEKRGIIVLPTGSGKTIIAMEIMRRLSVSTLVVVPT 120 Query: 121 LALLEQWKERLEIFGDVGEFSGRKKELKPITVTTYDSAYINAEFLGDKFFLLIFDECHHL 180 LALLEQWKERL IFG+VGEFSG+KKELKPITVTTYDSAYINAE LGDKF L+IFDECHHL Sbjct: 121 LALLEQWKERLSIFGEVGEFSGKKKELKPITVTTYDSAYINAELLGDKFMLIIFDECHHL 180 Query: 181 PSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELMGTYLAPYEL 240 P+EAYRNIAQMS APYRLGLTAFPER+DNLH+LLPDLIGP+VYKK P EL+GTYLAPYE+ Sbjct: 181 PAEAYRNIAQMSVAPYRLGLTAFPERSDNLHELLPDLIGPVVYKKGPGELIGTYLAPYEI 240 Query: 241 VRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALE 300 VR+KVPLSREER EY K+Y +FKRYL ESG+ IKSLEDFQ+IVM+TG+DNKAFKALRALE Sbjct: 241 VRIKVPLSREEREEYKKYYGIFKRYLEESGIEIKSLEDFQRIVMKTGMDNKAFKALRALE 300 Query: 301 EARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERV 360 ++RKIALGSK KIEELRKILERHRGEKIII TRYNELVYEISRKFLIPAITHKT K+ER Sbjct: 301 KSRKIALGSKGKIEELRKILERHRGEKIIIFTRYNELVYEISRKFLIPAITHKTDKKERS 360 Query: 361 EILRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKER 420 EIL+KFR+G Y AVVSSQVLDEGIDVPDASVG+IISGTGSPREL+QRLGRILR APGKE+ Sbjct: 361 EILKKFRKGIYKAVVSSQVLDEGIDVPDASVGVIISGTGSPRELIQRLGRILRSAPGKEK 420 Query: 421 AILYELITPGTTEVRISSRRLSGIKKL 447 AILYEL+TPGT EVRI+SRRLSG+KKL Sbjct: 421 AILYELVTPGTAEVRIASRRLSGLKKL 447 >gi|11497970 DNA repair protein RAD25 [Archaeoglobus fulgidus] >gi|7446073|pir||F69294 DNA repair protein RAD25 homolog - Archaeoglobus fulgidus >gi|2650278|gb|AAB90879.1| (AE001080) DNA repair protein RAD25 [Archaeoglobus fulgidus] Length = 452 Score = 535 bits (1363), Expect = e-151 Identities = 271/446 (60%), Positives = 347/446 (77%), Gaps = 4/446 (0%) Query: 2 KLYYDRGTIKVIGNSYVPYARWDERCRCYRALAYKYRDIVEFLESEGIEFEDYVLENALP 61 ++YY+RGTI V G+++VP+A++D R YRALA++YRDI+E+ ES GIEF D + +P Sbjct: 6 EIYYERGTIVVKGDAHVPHAKFDSRSGTYRALAFRYRDIIEYFESNGIEFVDNAAD-PIP 64 Query: 62 SRVYDDVEFELRDYQEEAVERWMREKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTL 121 + Y D E LRDYQE+A+ERW+ +KRG IVLPTG+GKT VAM I LS TL++VPTL Sbjct: 65 TP-YFDAEISLRDYQEKALERWLVDKRGCIVLPTGSGKTHVAMAAINELSTPTLIVVPTL 123 Query: 122 ALLEQWKERLEIFGD--VGEFSGRKKELKPITVTTYDSAYINAEFLGDKFFLLIFDECHH 179 AL EQWKERL IFG+ VGEFSGR KELKP+TV+TYDSAY+NAE LG++F LLIFDE HH Sbjct: 124 ALAEQWKERLGIFGEEYVGEFSGRIKELKPLTVSTYDSAYVNAEKLGNRFMLLIFDEVHH 183 Query: 180 LPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELMGTYLAPYE 239 LP+E+Y IAQMS AP+RLGLTA ER D H++L +++G V++ P L G +LA Y Sbjct: 184 LPAESYVQIAQMSIAPFRLGLTATFEREDGRHEILKEVVGGKVFELFPDSLAGKHLAKYT 243 Query: 240 LVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRAL 299 + R+ VPL+ +ER EY K KV+K++L G+ ++ EDF KIVM +G D +A++ALRA Sbjct: 244 IKRIFVPLAEDERVEYEKREKVYKQFLRARGITLRRAEDFNKIVMASGYDERAYEALRAW 303 Query: 300 EEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEER 359 EEAR+IA SK KI +LR+ILERHR +KIII TR+NELVY IS+ FLIPAITH+TS+EER Sbjct: 304 EEARRIAFNSKNKIRKLREILERHRKDKIIIFTRHNELVYRISKVFLIPAITHRTSREER 363 Query: 360 VEILRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKE 419 EIL FR G++ A+VSSQVLDEGIDVPDA+VG+I+SG+GS RE +QRLGRILRP+ GK+ Sbjct: 364 EEILEGFRTGRFRAIVSSQVLDEGIDVPDANVGVIMSGSGSAREYIQRLGRILRPSKGKK 423 Query: 420 RAILYELITPGTTEVRISSRRLSGIK 445 A+LYELI+ GT EV + RR + K Sbjct: 424 EAVLYELISRGTGEVNTARRRKNAAK 449 >gb|AAK40796.1| DNA repair protein rad25 [Sulfolobus solfataricus] Length = 444 Score = 409 bits (1041), Expect = e-113 Identities = 212/424 (50%), Positives = 293/424 (69%), Gaps = 5/424 (1%) Query: 19 PYARWDERCRCYRALAYKYRDIVEFLESEGIEFEDYVLENALPSRVYDDVEFELRDYQEE 78 P W++ +CY A KYR+++ + + +E ED VLE LP + D +LR+YQ+E Sbjct: 18 PGLSWNDEFKCYIGQANKYREVLYYYKRSHVEVEDSVLE-LLPFPLIVD-RIKLREYQQE 75 Query: 79 AVERWMREKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWKERL-EIFG-D 136 A+ W++ K G+IV+PTG GKT++ ++ I + L+TL+IVPT+ LL+QW E + E+ G + Sbjct: 76 ALNAWLKSKLGIIVIPTGGGKTVIGLKAIALIRLATLIIVPTIDLLQQWYENIRELLGVE 135 Query: 137 VGEFSGRKKELKPITVTTYDSAYINAEFLGDKFFLLIFDECHHLPSEAYRNIAQMSAAPY 196 G G ELK ITV TYDSAY E +G+KF L+IFDE HHLPSE Y IAQ AAPY Sbjct: 136 AGRVGGGYDELKGITVITYDSAYTQLEKIGNKFGLVIFDEVHHLPSEGYSIIAQGLAAPY 195 Query: 197 RLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELMGTYLAPYELVRVKVPLSREERAEYL 256 RLGLTA PER+D H L P L+GP+VY+ L+G YL+ +E+ R+ V L+ +E Y Sbjct: 196 RLGLTATPERSDGRHKLYPSLVGPLVYRITVSNLVGKYLSSFEIQRIYVNLTEDEEKLYR 255 Query: 257 KHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKIALGSKAKIEEL 316 + + K++LS+ L++KSL DF +++ D +A +AL A EA KIA+ SKAK+E+L Sbjct: 256 HYRGILKKFLSQRNLKLKSLNDFNRLLRLAVKDKEAREALLAWHEALKIAVNSKAKLEKL 315 Query: 317 RKILERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERVEILRKFREGKYMAVVS 376 + +L+ GEKIII TR +VYEISR FLIPA+T+KT+K+ER+EIL KFR GKY +V+ Sbjct: 316 KDLLKELNGEKIIIFTRNTSMVYEISRLFLIPAVTYKTNKQERIEILEKFRSGKYNVIVT 375 Query: 377 SQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKERAILYELITPGTTEVRI 436 S VLDEGIDVPDAS+GI++ G G+ R+ +QRLGRILR K +A L E+IT GT++ + Sbjct: 376 SSVLDEGIDVPDASIGIVLGGYGTSRQFIQRLGRILRKKENK-KARLIEIITKGTSDYNL 434 Query: 437 SSRR 440 S RR Sbjct: 435 SKRR 438 >gi|10803640 ORF H1047 [Halobacterium sp. NRC-1] >gi|7446116|pir||T08310 helicase homolog H1047 - Halobacterium sp. (strain NRC-1) plasmid pNRC100 >gi|2822371|gb|AAC82877.1| (AF016485) ORF H1047 [Halobacterium sp. NRC-1] >gi|10584184|gb|AAG20805.1| (AE005148) DNA repair protein; Rad25 [Halobacterium sp. NRC-1] Length = 469 Score = 367 bits (933), Expect = e-100 Identities = 203/463 (43%), Positives = 290/463 (61%), Gaps = 19/463 (4%) Query: 1 MKLYYDRGTIKVI-GNSYVPYARWDERCRCYRALAYKYRDIVEFLE--------SEGIEF 51 M+L +D GT+ + + VPYA WD+R YRA A Y+D+ ++ + ++ Sbjct: 1 MRLAFDDGTLLLEDAPNSVPYADWDDRVDEYRARALHYQDLCQWAQGPDGQATLNQASHT 60 Query: 52 EDYVLENALPSRVYD---DVEFELRDYQEEAVERWM-REKRGVIVLPTGAGKTIVAMEII 107 ++ + ++A R D V E RDYQ+ A+ W ++RG +VLPTG+GKT +A++ I Sbjct: 61 DESLHDDARAYRDLDLTPAVAIEPRDYQQAALAAWTDHDRRGSVVLPTGSGKTFLAVQAI 120 Query: 108 KRLSLSTLVIVPTLALLEQWKERL-EIFGD-----VGEFSGRKKELKPITVTTYDSAYIN 161 S+STLV+VPT+ LL QW L FGD +G G + ITVTTYDSAY Sbjct: 121 ADASVSTLVVVPTIDLLNQWHATLTNAFGDQLPHEIGVLGGGSHNVTDITVTTYDSAYRY 180 Query: 162 AEFLGDKFFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPI 221 GD+F LL+ DE HHLP+ Y+ I +M+ APYRLGLTA ER D H++L DLIGP+ Sbjct: 181 INEYGDQFGLLVVDEVHHLPAPTYQQIPEMTIAPYRLGLTATYERTDGEHNVLEDLIGPV 240 Query: 222 VYKKAPRELMGTYLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQK 281 VY++ EL G YL+ YE + +KV L+ EER +Y Y++++ YL + I + +Q+ Sbjct: 241 VYEENVDELAGEYLSEYETIHLKVDLTPEERNQYDDEYQIYRDYLDNHDVDIWKQDGYQE 300 Query: 282 IVMRTGVDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEI 341 + RT D +AL A + A +IA ++ K++ L +L+RH ++ II T N+ Y+I Sbjct: 301 FLKRTSYDPDGRRALIAKQRAEEIARTAEKKLDTLDNLLKRHYNDRTIIFTANNDFAYDI 360 Query: 342 SRKFLIPAITHKTSKEERVEILRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSP 401 S++F++P ITH+T +ER EIL +FR G+Y +V+SQVLDEGIDVP A+VGII+SG+ S Sbjct: 361 SQEFIVPCITHQTQTDERTEILERFRTGEYSMLVTSQVLDEGIDVPAANVGIILSGSASK 420 Query: 402 RELVQRLGRILRPAPGKERAILYELITPGTTEVRISSRRLSGI 444 R+ QRLGRILRP +E A LYELIT T E +S RR G+ Sbjct: 421 RQYAQRLGRILRPTEDREPARLYELITDDTMEQYVSKRRRQGV 463 >emb|CAC12145.1| (AL445066) DNA repair protein RAD25 related protein [Thermoplasma acidophilum] Length = 453 Score = 337 bits (854), Expect = 2e-91 Identities = 191/448 (42%), Positives = 279/448 (61%), Gaps = 12/448 (2%) Query: 3 LYYDRGTIKVIG---NSYVPYARWDERCRCYRALAYKYRDIVEFLESEGIEFEDYVLENA 59 + Y G+I + G N A +D R CYR+L Y I+ F GI+ D V++ Sbjct: 4 IVYSGGSILIKGYDGNIPEDLAVFDHRIACYRSLGVNYPRILSFFRDAGIDAVDRVMDR- 62 Query: 60 LPSRVYDDVEFELRDYQEEAVERWMRE-KRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIV 118 + + LR YQ +A+E W + RG +VLPT AGKT + M I+ +S L++V Sbjct: 63 --KHLNLNGRISLRPYQLQALEEWKKYGMRGTVVLPTAAGKTHIGMAAIQAVSERALILV 120 Query: 119 PTLALLEQWKERL-EIFG-DVGEFSGRKKELKPITVTTYDSAYINAEFLGDKFFLLIFDE 176 PT+ LL QWK+R+ E FG + G+ G + + + ITV+TYDSAY+ AE G++F L+I DE Sbjct: 121 PTIDLLSQWKKRIQETFGVEPGQIGGGEHDERDITVSTYDSAYLMAEKYGNRFSLIIADE 180 Query: 177 CHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELMGTYLA 236 HHL SE R I M AP+R+GLTA ER D L +L ++G +++ E+ YLA Sbjct: 181 VHHLASEKLRMIPLMYTAPFRMGLTATYERTDGLQKVLEQIMGGKIFELGYEEI-DEYLA 239 Query: 237 PYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKAL 296 Y + R+ + LS EE A+Y +++++F YL + ++ DF+K + R+ + +AL Sbjct: 240 DYTIARIPIELSDEEYADYQRYHEIFVSYLRRHRMVMRGPWDFEKFI-RSSWTPEGREAL 298 Query: 297 RALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSK 356 A ++R+IA S+ K+E +R IL +HRGEK +I E Y IS++FLIPAIT+ T K Sbjct: 299 IAWRKSREIAFNSRGKMEMIRTILSKHRGEKTLIFAEDTETAYTISKEFLIPAITYLTDK 358 Query: 357 EERVEILRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAP 416 EER +I FREG+ A+ +S+VLDEG+D PDASV I++SG+GS R+ QRLGRILRP+ Sbjct: 359 EEREKIPAMFREGRITAIATSRVLDEGVDFPDASVAIVVSGSGSMRQFRQRLGRILRPSA 418 Query: 417 GKERAILYELITPGTTEVRISSRRLSGI 444 GK +A++YEL+T T+E +S RR G+ Sbjct: 419 GK-KAVMYELVTAETSEFGVSRRRRKGV 445 >gb|AAF69763.1| (AF068771) similar to RAD25 [Synechocystis PCC9413] Length = 449 Score = 295 bits (747), Expect = 7e-79 Identities = 168/377 (44%), Positives = 236/377 (62%), Gaps = 7/377 (1%) Query: 71 ELRDY--QEEAVERWMREKR-GVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQW 127 E+R Y Q EA++ W R G++VLPT AGKT +A ++ STL++VPTL L+ QW Sbjct: 26 EMRPYAHQSEALQAWKEAGRQGIVVLPTAAGKTYLAQLAMQATPRSTLIVVPTLDLMHQW 85 Query: 128 -KERLEIFGD--VGEFSGRKKELKPITVTTYDSAYINAEFLGDKFFLLIFDECHHLPSEA 184 + L F D +G G ++ I V TYDSA I+AE LG ++ IFDECHHLP++ Sbjct: 86 YAQLLAAFPDAEIGLLGGGSRDRTSILVATYDSAAIHAESLGSQYAFAIFDECHHLPTDF 145 Query: 185 YRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELMGTYLAPYELVRVK 244 YR IA+ S APYRLGLTA ER+D L +LIG IVY+K P EL GT LA +++ ++K Sbjct: 146 YRPIAEYSIAPYRLGLTATIERSDGRDRDLLNLIGDIVYQKTPEELAGTALAHHKIAQIK 205 Query: 245 VPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARK 304 V LS ER Y + + +L + + S+E ++ V + +A+ A +AR+ Sbjct: 206 VKLSVRERETYQRLIQERNEFLRSQNISLGSMEGWKMFVQASARSAAGRRAMLAHRQARE 265 Query: 305 IALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERVEILR 364 IAL + K+ L +L +H E II T N VY+IS+ LIPAITH+T +ER EIL Sbjct: 266 IALITDGKLRVLINLLGQHYPESTIIFTADNATVYKISKALLIPAITHQTPVKERHEILT 325 Query: 365 KFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPG-KERAIL 423 +F+ G Y +++S VL+EG+DVP+A + I++SGTGS RE +QRLGR+LR +++AIL Sbjct: 326 RFKAGDYKTLIASHVLNEGVDVPEARIAIVLSGTGSRREYIQRLGRVLRKGQNDQKQAIL 385 Query: 424 YELITPGTTEVRISSRR 440 YE+I T E S+RR Sbjct: 386 YEVIAEDTVEEGTSARR 402 >pir||B72707 hypothetical protein APE1073 - Aeropyrum pernix (strain K1) >gi|5104743|dbj|BAA80058.1| (AP000060) 539aa long hypothetical protein [Aeropyrum pernix] Length = 539 Score = 276 bits (698), Expect = 4e-73 Identities = 178/432 (41%), Positives = 248/432 (57%), Gaps = 22/432 (5%) Query: 23 WDERCRCYRALAYKYRDIVEFLESEGIEFEDYVL---ENALPSRVYDDVEFELRDYQEEA 79 +D R YRA Y + E E G++ ED V +LP V ELRDYQEEA Sbjct: 117 YDREARAYRAPPIMYPRLREAFERRGLKVEDRVFPPSSRSLPRPVR--FTGELRDYQEEA 174 Query: 80 VERWMREK-RGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWKERLEIFGD-- 136 +E W + RGVIVLPTGAGKT+VA+ + + +L++V T + QW + F D Sbjct: 175 LEAWRKAGGRGVIVLPTGAGKTVVAIAAVAWAGVWSLIVVYTRDHVRQWIDAFRRFTDAH 234 Query: 137 --VGEFSGRKKELKPITVTTYDSAYINAEFLGDKFFLLIFDECHHLPSEAYRNIAQMSAA 194 VG + G +K L PITVTTY +AY + + L F L+FDE HH+P++ ++ IA S A Sbjct: 235 SLVGAYYGEEKRLAPITVTTYQTAYRHIDRLAPLFPFLVFDEAHHIPADKFKRIASASPA 294 Query: 195 PYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELMGT-YLAPYELVRVKVPLSREERA 253 PYR+GL+A ER D H+ + L+G +VY +P EL YLAP+ + RVKV L EE+ Sbjct: 295 PYRMGLSATIEREDGRHEEVYSLVGGVVYSSSPGELTRKGYLAPFVIRRVKVELEEEEKR 354 Query: 254 EYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKIALGSKAKI 313 Y + K R L+ K LED ++ D A +A+R ++I S++KI Sbjct: 355 LY-EDLKRKYRILARGRSFEKILEDARR------GDPTAIEAIRVNTRMKEIVQLSESKI 407 Query: 314 EELRKIL--ERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERVEILRKFREGKY 371 + K++ E RG K+I+ T+Y EI+R+ + + R L KFR K Sbjct: 408 RAVEKLVREELSRGSKVIVFTQYRRQAEEIARRTGALLLHGGLERRVREATLAKFRALKA 467 Query: 372 MAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKERAILYELITPGT 431 A+V + V DEG+D+PDA+VGI++SGTGS R+ +QRLGR+LRP GK RA+LYE+I GT Sbjct: 468 GALVVTTVGDEGLDIPDANVGILVSGTGSRRQFIQRLGRLLRPGEGK-RAVLYEVIARGT 526 Query: 432 TEVRISSRRLSG 443 E + SRR G Sbjct: 527 GE-ELQSRRRRG 537 >gb|AAK41233.1| DNA repair protein rad25 [Sulfolobus solfataricus] Length = 551 Score = 273 bits (692), Expect = 2e-72 Identities = 169/429 (39%), Positives = 254/429 (58%), Gaps = 26/429 (6%) Query: 22 RWDERCRCYRALAYKYRDIVEFLESEGIEFEDYVLENALPSRVYDDVEFE----LRDYQE 77 R+D++ R + Y ++++ L G+E ++ L + + EFE LR+YQ Sbjct: 117 RYDKQNRRFIVRPMDYFNLLQKLRENGLEVKELNLS-------FKEFEFEFNGQLREYQR 169 Query: 78 EAVERWMRE-KRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWKERLEIFG- 135 EA+E W++ +GVI LPTGAGKT+V ++ I + TL++ T + QWKE + F Sbjct: 170 EAIENWIKNGNKGVIALPTGAGKTVVGIKGIDIIRKPTLIVTFTKEQMLQWKEAILKFTS 229 Query: 136 ---DVGEFSGRKKELKPITVTTYDSAYINAEFLGDKFFLLIFDECHHLPSEAYRNIAQMS 192 D+G + +K ++PIT+TTY +AY + L DKF+LLI DE HHLP++ ++ IA+ Sbjct: 230 KRPDIGLYYSEEKRIRPITITTYHTAYRHLPQLFDKFYLLIVDEVHHLPADKFKLIAEGL 289 Query: 193 AAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELMGT-YLAPYELVRVKVPLSREE 251 APYR+GL+A P R DN H+ L LIG I+Y K+ EL YLA YE+++ KV L+ EE Sbjct: 290 IAPYRMGLSATPHREDNKHNELFSLIGGIIYYKSVTELAKLGYLASYEIIQKKVRLTLEE 349 Query: 252 RAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKIALGSKA 311 R Y + FK G ++ L + K D A +A+R E RKI + Sbjct: 350 RKRYNELLNRFKAL--SKGRKVSELIELVK-----KGDESAIEAMRVYNEMRKIVNFASE 402 Query: 312 KIEELRKILERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERVEILRKFREGKY 371 K++ L +IL+ +G KI+I T+Y + EI++++ +T K SKEER +L F+ Sbjct: 403 KMKALDEILKSEKG-KILIFTQYIDQAEEIAKRYNSLLLTGKMSKEERKRVLVTFKTMNA 461 Query: 372 MAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKERAILYELITPGT 431 +V + V DEGID+PDA+VGII++GT S R+ +QRLGRI+RP GK+ A LYE++ GT Sbjct: 462 GVLVLTTVGDEGIDIPDANVGIIVTGTSSRRQFIQRLGRIMRPYNGKQ-AKLYEIVVSGT 520 Query: 432 TEVRISSRR 440 E + +R Sbjct: 521 PEEYQAKKR 529 >pir||E70815 hypothetical protein Rv0861c - Mycobacterium tuberculosis (strain H37RV) >gi|2916920|emb|CAA17667.1| (AL022004) hypothetical protein Rv0861c [Mycobacterium tuberculosis] Length = 542 Score = 160 bits (401), Expect = 3e-38 Identities = 119/402 (29%), Positives = 188/402 (46%), Gaps = 56/402 (13%) Query: 54 YVLENALPSRVYDDVEFELRDYQEEAVERWMREKRGVIVLPTGAGKTIVAMEIIKRLSLS 113 YV A P ++ + ++LRDYQ A + + GV+VLP GAGKT+V + + + Sbjct: 158 YVDGEAHPISLHQE-GWQLRDYQRLAADSFWAGGSGVVVLPCGAGKTLVGAAAMAKAGAT 216 Query: 114 TLVIVPTLALLEQWKERLE-----IFGDVGEFSGRKKELKPITVTTYD-------SAYIN 161 TL++V + QWK L ++GEFSG +KE++P+T++TY Y + Sbjct: 217 TLILVTNIVAARQWKRELVARTSLTENEIGEFSGERKEIRPVTISTYQMITRRTKGEYRH 276 Query: 162 AEFLGDK-FFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGP 220 E + + L+I+DE H LP+ +R A + + RLGLTA R D + LIGP Sbjct: 277 LELFDSRDWGLIIYDEVHLLPAPVFRMTADLQ-SKRRLGLTATLIREDGREGDVFSLIGP 335 Query: 221 IVYKKAPRELMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDF 279 Y +++ ++AP E V V+V ++ ER Y Sbjct: 336 KRYDAPWKDIEAQGWIAPAECVEVRVTMTDSERMMY------------------------ 371 Query: 280 QKIVMRTGVDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVY 339 A EE +I KI ++ IL +H E+ ++ Y + + Sbjct: 372 ---------------ATAEPEERYRICSTVHTKIAVVKSILAKHPDEQTLVIGAYLDQLD 416 Query: 340 EISRKFLIPAITHKTSKEERVEILRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGT- 398 E+ + P I T ER + FR G+ +V S+V + ID+P+A+V + +SGT Sbjct: 417 ELGAELGAPVIQGSTRTSEREALFDAFRRGEVATLVVSKVANFSIDLPEAAVAVQVSGTF 476 Query: 399 GSPRELVQRLGRILRPAPGKERAILYELITPGTTEVRISSRR 440 GS +E QRLGRILRP AI Y ++ + + ++ R Sbjct: 477 GSRQEEAQRLGRILRPKADGGGAIFYSVVARDSLDAEYAAHR 518 >pir||F71330 probable DNA repair helicase - syphilis spirochete >gi|3322660|gb|AAC65366.1| (AE001217) DNA repair helicase, putative [Treponema pallidum] Length = 606 Score = 153 bits (382), Expect = 5e-36 Identities = 117/393 (29%), Positives = 194/393 (48%), Gaps = 64/393 (16%) Query: 70 FELRDYQEEAVERWMREKR-----GVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALL 124 F RDYQ EA + ++ + GV+VLP GAGKT+V + ++ L TL++ P A Sbjct: 235 FVPRDYQWEAADAFVGNRTQGSGFGVVVLPCGAGKTVVGLLVMGLLQTDTLILTPNSAAA 294 Query: 125 EQWK----ERLEIFG-DVGEFSGRKKELKPITVTTYD----SAYINAEFLGDKFF----- 170 +QWK E+ ++ G +G +SG KE++P+T+ TY A+ +A F + F Sbjct: 295 QQWKRELCEKTDLDGTSIGIYSGECKEIRPVTIATYQILTWRAHADAPFSHFRLFMERSW 354 Query: 171 -LLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRE 229 L+I+DE H LP+ +R A++ RLGLTA R D + L+GP Y ++ Sbjct: 355 GLIIYDEVHLLPAPLFRITAELQVV-RRLGLTATLVREDGCAQDVFSLVGPKRYDVPWKD 413 Query: 230 LMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGV 288 L ++A V V+V + R + +Y+ + +R++ Sbjct: 414 LEARGWIARVRCVEVRVTMDRSLQYQYM-----------TAPVRLR-------------- 448 Query: 289 DNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLIP 348 ++A ++AK+ ++++L H G +I +Y + + ++ +P Sbjct: 449 --------------HRLASENEAKVAVVQRLLRAHAGAPTLIIGQYVQQLLHLAHVLQVP 494 Query: 349 AITHKTSKEERVEILRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGT-GSPRELVQR 407 ++ + + R I ++FREG +V S+V + +D+PDASV I +SGT GS +E QR Sbjct: 495 LVSGRQTYAAREAIYQRFREGTLQVLVVSKVANCALDLPDASVAIQVSGTFGSRQEEAQR 554 Query: 408 LGRILRPAPGKERAILYELITPGTTEVRISSRR 440 LGR+LRP A Y L+T T E + RR Sbjct: 555 LGRLLRPKICD--AHFYSLVTEQTVEEDCALRR 585 >pir||H71243 probable helicase protein PH0210 - Pyrococcus horikoshii >gi|3256596|dbj|BAA29279.1| (AP000001) 444aa long hypothetical protein [Pyrococcus horikoshii] Length = 444 Score = 129 bits (322), Expect = 5e-29 Identities = 113/419 (26%), Positives = 197/419 (46%), Gaps = 55/419 (13%) Query: 20 YARWDERCRCYRALAYKYR-----DIVEFLESEG--IEFEDYVLENALPSRVYDDVEFEL 72 + RWD+ Y + + ++L S+G + +D + P + E++L Sbjct: 36 FGRWDKAESLYDPYTNTFPIGLLPRVKKYLNSKGYKVRVKDERVIEGEPLNSQWNEEYKL 95 Query: 73 RDYQEEAVERWMREKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWKERL- 131 R YQ++AV+ ++EK GV+ LP G+GKT+V + II ++ S LVIV T LL QW ++ Sbjct: 96 RKYQKKAVKLAIKEKMGVLALPVGSGKTVVGLRIIHEINKSALVIVHTKELLYQWANKVR 155 Query: 132 EIFG-DVGEFSGRKKELKPITVTTYDSAYI-NAEFLGDKFFLLIFDECHHL-PSEAYRNI 188 EI G + G K PITV + + L +K+ +++FDECH +E + + Sbjct: 156 EILGVEPGIIGDNKWSEGPITVAMIQTLLSRGTDKLQNKYAIVMFDECHRTSAAEKFYKV 215 Query: 189 AQMSAAPYRLGLTAFPERADNLHDL-LPDLIGPIVYKKAPRELMGTYLAPYELVRVKVPL 247 YR GL+A P R ++ + ++GPI+Y+ +L+ Sbjct: 216 GISLPQVYRFGLSATPWRRLRGEEMKIEGVVGPIIYEVKAEDLI---------------- 259 Query: 248 SREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKIAL 307 +E ++V + L K E +++ VM N+A +E+A ++A Sbjct: 260 --KEGFLAKPKFEVIEYDSKMPALADKYKELYEEAVMENEERNRAI-----VEKAIELA- 311 Query: 308 GSKAKIEELRKILERHRGEKIIISTR---YNELVYEISRKFLIPAITHKTSKEERVEILR 364 +G +++I + + E++ ++ R I A + R EIL Sbjct: 312 ---------------KQGHRVLIDVKRIDHGEILVKMLRDRGINAEFLSSQSPNRWEILE 356 Query: 365 KFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKERAIL 423 K+++G+ +VS+ +L EG+D+P+ S I+ G S +Q +GR LRP PG E I+ Sbjct: 357 KYKKGEIPVLVST-LLKEGVDIPEISAIILAGGGKSDVMTIQTIGRALRPKPGGEAVIV 414 >gb|AAC49987.1| (U29168) putative DNA repair protein and transcription factor [Arabidopsis thaliana] >gi|9758046|dbj|BAB08509.1| (AB006707) DNA excision repair cross-complementing protein; similar to human Xeroderma pigmentosum group B DNA repair protein [Arabidopsis thaliana] Length = 755 Score = 127 bits (316), Expect = 3e-28 Identities = 126/431 (29%), Positives = 196/431 (45%), Gaps = 80/431 (18%) Query: 52 EDYVLENALPSRVYDDVEFEL------RDYQEEAVERWM---REKRGVIVLPTGAGKTIV 102 E+Y N V D++ EL R YQE+++ + R + G+IVLP GAGK++V Sbjct: 247 EEYDFRN---DNVNPDLDMELKPHAQPRPYQEKSLSKMFGNGRARSGIIVLPCGAGKSLV 303 Query: 103 AMEIIKRLSLSTLVIVPTLALLEQWKERLEIFGDVGE-----FSGRKKEL----KPITVT 153 + R+ S L + ++QW + +++ + + F+ KE + VT Sbjct: 304 GVSAAARIKKSCLCLATNAVSVDQWAFQFKLWSTIRDDQICRFTSDSKERFRGNAGVVVT 363 Query: 154 TY-----------DSAYINAEFLGDKFFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTA 202 TY +S I E ++ LL+ DE H +P+ +R + ++ + +LGLTA Sbjct: 364 TYNMVAFGGKRSEESEKIIEEMRNREWGLLLMDEVHVVPAHMFRKVISITKSHCKLGLTA 423 Query: 203 FPERADNLHDLLPDLIGPIVYKKAPRELM-GTYLAPYELVRVKVPLSREERAEYLKHYKV 261 R D L LIGP +Y+ +L+ G ++A + V P+++E AEYLK Sbjct: 424 TLVREDERITDLNFLIGPKLYEANWLDLVKGGFIANVQCAEVWCPMTKEFFAEYLKK--- 480 Query: 262 FKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKIALGSKAKIEELRKILE 321 E+ +K ++ F+A E L + E Sbjct: 481 ---------------ENSKKKQALYVMNPNKFRA-----------------CEFLIRFHE 508 Query: 322 RHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERVEILRKFREGKYM-AVVSSQVL 380 + RG+KII+ + E + K P I TS ER +IL F+ K + V S+V Sbjct: 509 QQRGDKIIVFADNLFALTEYAMKLRKPMIYGATSHIERTKILEAFKTSKDVNTVFLSKVG 568 Query: 381 DEGIDVPDASVGIIISG-TGSPRELVQRLGRILRP--------APGKE--RAILYELITP 429 D ID+P+A+V I IS GS R+ QRLGRILR A GKE A Y L++ Sbjct: 569 DNSIDIPEANVIIQISSHAGSRRQEAQRLGRILRAKGKLEDRMAGGKEEYNAFFYSLVST 628 Query: 430 GTTEVRISSRR 440 T E+ S++R Sbjct: 629 DTQEMYYSTKR 639 >gb|AAG27465.1|AF308595_1 (AF308595) putative DNA repair protein and transcription factor [Arabidopsis thaliana] Length = 766 Score = 127 bits (315), Expect = 3e-28 Identities = 125/431 (29%), Positives = 196/431 (45%), Gaps = 80/431 (18%) Query: 52 EDYVLENALPSRVYDDVEFEL------RDYQEEAVERWM---REKRGVIVLPTGAGKTIV 102 E+Y N V D++ EL R YQE+++ + R + G+IVLP GAGK++V Sbjct: 259 EEYDFRN---DNVNPDLDMELKPHAQPRPYQEKSLSKMFGNGRARSGIIVLPCGAGKSLV 315 Query: 103 AMEIIKRLSLSTLVIVPTLALLEQWKERLEIFGDVGE-----FSGRKKEL----KPITVT 153 + R+ S L + ++QW + +++ + + F+ KE + VT Sbjct: 316 GVSAAARIKKSCLCLATNAVSVDQWAYQFKLWSTIKDDQICRFTSDSKERFRGNAGVVVT 375 Query: 154 TY-----------DSAYINAEFLGDKFFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTA 202 TY ++ I E ++ LL+ DE H +P+ +R + ++ + +LGLTA Sbjct: 376 TYNMIAFGGKRSEEAEKIIEEMRNREWGLLLMDEVHVVPAHMFRKVISITKSHCKLGLTA 435 Query: 203 FPERADNLHDLLPDLIGPIVYKKAPRELM-GTYLAPYELVRVKVPLSREERAEYLKHYKV 261 R D L LIGP +Y+ +L+ G ++A + V P+++E AEYLK Sbjct: 436 TLVREDEKITDLNFLIGPKLYEANWLDLVKGGFIANVQCAEVWCPMTKEFFAEYLKK--- 492 Query: 262 FKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKIALGSKAKIEELRKILE 321 E+ +K ++ F+A E L + E Sbjct: 493 ---------------ENSKKKQALYVMNPNKFRA-----------------CEFLIRFHE 520 Query: 322 RHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERVEILRKFREGKYM-AVVSSQVL 380 + RG+KII+ + E + K P I TS ER +IL F+ K + V S+V Sbjct: 521 QQRGDKIIVFADNLFALTEYAMKLRKPMIYGATSHIERTKILEAFKTSKTVNTVFLSKVG 580 Query: 381 DEGIDVPDASVGIIISG-TGSPRELVQRLGRILRP--------APGKE--RAILYELITP 429 D ID+P+A+V I IS GS R+ QRLGRILR A GKE A Y L++ Sbjct: 581 DNSIDIPEANVIIQISSHAGSRRQEAQRLGRILRAKGKLEDRMAGGKEEYNAFFYSLVST 640 Query: 430 GTTEVRISSRR 440 T E+ S++R Sbjct: 641 DTQEMYYSTKR 651 >dbj|BAB08508.1| (AB006707) DNA excision repair cross-complementing protein [Arabidopsis thaliana] Length = 754 Score = 127 bits (315), Expect = 3e-28 Identities = 125/431 (29%), Positives = 196/431 (45%), Gaps = 80/431 (18%) Query: 52 EDYVLENALPSRVYDDVEFEL------RDYQEEAVERWM---REKRGVIVLPTGAGKTIV 102 E+Y N V D++ EL R YQE+++ + R + G+IVLP GAGK++V Sbjct: 247 EEYDFRN---DNVNPDLDMELKPHAQPRPYQEKSLSKMFGNGRARSGIIVLPCGAGKSLV 303 Query: 103 AMEIIKRLSLSTLVIVPTLALLEQWKERLEIFGDVGE-----FSGRKKEL----KPITVT 153 + R+ S L + ++QW + +++ + + F+ KE + VT Sbjct: 304 GVSAAARIKKSCLCLATNAVSVDQWAYQFKLWSTIKDDQICRFTSDSKERFRGNAGVVVT 363 Query: 154 TY-----------DSAYINAEFLGDKFFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTA 202 TY ++ I E ++ LL+ DE H +P+ +R + ++ + +LGLTA Sbjct: 364 TYNMIAFGGKRSEEAEKIIEEMRNREWGLLLMDEVHVVPAHMFRKVISITKSHCKLGLTA 423 Query: 203 FPERADNLHDLLPDLIGPIVYKKAPRELM-GTYLAPYELVRVKVPLSREERAEYLKHYKV 261 R D L LIGP +Y+ +L+ G ++A + V P+++E AEYLK Sbjct: 424 TLVREDEKITDLNFLIGPKLYEANWLDLVKGGFIANVQCAEVWCPMTKEFFAEYLKK--- 480 Query: 262 FKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKIALGSKAKIEELRKILE 321 E+ +K ++ F+A E L + E Sbjct: 481 ---------------ENSKKKQALYVMNPNKFRA-----------------CEFLIRFHE 508 Query: 322 RHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERVEILRKFREGKYM-AVVSSQVL 380 + RG+KII+ + E + K P I TS ER +IL F+ K + V S+V Sbjct: 509 QQRGDKIIVFADNLFALTEYAMKLRKPMIYGATSHIERTKILEAFKTSKTVNTVFLSKVG 568 Query: 381 DEGIDVPDASVGIIISG-TGSPRELVQRLGRILRP--------APGKE--RAILYELITP 429 D ID+P+A+V I IS GS R+ QRLGRILR A GKE A Y L++ Sbjct: 569 DNSIDIPEANVIIQISSHAGSRRQEAQRLGRILRAKGKLEDRMAGGKEEYNAFFYSLVST 628 Query: 430 GTTEVRISSRR 440 T E+ S++R Sbjct: 629 DTQEMYYSTKR 639 >pir||A75209 DNA repair protein rad25 PAB0128 - Pyrococcus abyssi (strain Orsay) >gi|5457629|emb|CAB49120.1| (AJ248283) DNA repair protein RAD25 [Pyrococcus abyssi] Length = 446 Score = 124 bits (309), Expect = 2e-27 Identities = 109/421 (25%), Positives = 199/421 (46%), Gaps = 59/421 (14%) Query: 20 YARWDERCRCYRALAYKYR-----DIVEFLESEGIEF---EDYVLENALPSRVYDDVEFE 71 + RWD+ Y + + +FL S+G ++ V++ + +++ ++ Sbjct: 36 FGRWDKAESLYDPYTNTFPVGLLPRVKKFLNSKGYRVKVKDERVIDGVKINSTWNE-NYK 94 Query: 72 LRDYQEEAVERWMREKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWKERL 131 LR YQ++AV+ ++EK GV+ LP G+GKT+V + II + S L+IV T LL QW +++ Sbjct: 95 LRKYQKKAVKLAIKEKMGVLALPVGSGKTVVGLRIIHEIGRSALIIVHTKELLYQWADKV 154 Query: 132 -EIFG-DVGEFSGRKKELKPITVTTYDSAYI-NAEFLGDKFFLLIFDECHHL-PSEAYRN 187 EI G + G K ITV + + L +K+ +++FDECH +E + Sbjct: 155 KEILGIEPGIIGDNKWSEGDITVAMIQTLLSRGTDKLQNKYAIVMFDECHRTSAAEKFYE 214 Query: 188 IAQMSAAPYRLGLTAFPERADNLHDL-LPDLIGPIVYKKAPRELMGT-YLAPYELVRVKV 245 + YR GL+A P R ++ + ++GPI+Y+ +L+ +LA Sbjct: 215 VGISLPQVYRFGLSATPWRRLRGEEMKIEGVVGPIIYEVKAEDLINEGFLAK-------- 266 Query: 246 PLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKI 305 ++V + L K E +++ +M NKA +E+A ++ Sbjct: 267 -----------PKFEVIEYNSKMPALADKYKELYEEAIMENEERNKAI-----VEKAIEL 310 Query: 306 ALGSKAKIEELRKILERHRGEKIIISTR---YNELVYEISRKFLIPAITHKTSKEERVEI 362 A ++G +++I + + E++ ++ ++ + A + R EI Sbjct: 311 A----------------NQGHRVLIDVKRIDHGEILVKMLKERGVNAEFLSSQSPNRWEI 354 Query: 363 LRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKERAI 422 L KF+ G+ +VS+ +L EG+D+P+ S I+ G S +Q +GR LRP G E I Sbjct: 355 LEKFKNGEIPVLVST-LLKEGVDIPEISAIILAGGGKSDVMTIQTIGRALRPKAGGEAVI 413 Query: 423 L 423 + Sbjct: 414 V 414 >pir||S71206 DNA excision repair cross-complementing protein ERCC3 - Arabidopsis thaliana Length = 757 Score = 124 bits (308), Expect = 2e-27 Identities = 126/433 (29%), Positives = 195/433 (44%), Gaps = 82/433 (18%) Query: 52 EDYVLENALPSRVYDDVEFEL------RDYQEEAVERWM-----REKRGVIVLPTGAGKT 100 E+Y N V D++ EL R YQE+++ R + G+IVLP GAGK+ Sbjct: 247 EEYDFRN---DNVNPDLDMELKPHAQPRPYQEKSLRASKMFGNGRARSGIIVLPCGAGKS 303 Query: 101 IVAMEIIKRLSLSTLVIVPTLALLEQWKERLEIFGDVGE-----FSGRKKEL----KPIT 151 +V + R+ S L + ++QW + +++ + + F+ KE + Sbjct: 304 LVGVSAAARIKKSCLCLATNAVSVDQWAFQFKLWSTIRDDQICRFTSDSKERFRGNAGVV 363 Query: 152 VTTY-----------DSAYINAEFLGDKFFLLIFDECHHLPSEAYRNIAQMSAAPYRLGL 200 VTTY +S I E ++ LL+ DE H +P+ +R + ++ + +LGL Sbjct: 364 VTTYNMVAFGGKRSEESEKIIEEMRNREWGLLLMDEVHVVPAHMFRKVISITKSHCKLGL 423 Query: 201 TAFPERADNLHDLLPDLIGPIVYKKAPRELM-GTYLAPYELVRVKVPLSREERAEYLKHY 259 TA R D L LIGP +Y+ +L+ G ++A + V P+++E AEYLK Sbjct: 424 TATLVREDERITDLNFLIGPKLYEANWLDLVKGGFIANVQCAEVWCPMTKEFFAEYLKK- 482 Query: 260 KVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKIALGSKAKIEELRKI 319 E+ +K ++ F+A E L + Sbjct: 483 -----------------ENSKKKQALYVMNPNKFRA-----------------CEFLIRF 508 Query: 320 LERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERVEILRKFREGKYM-AVVSSQ 378 E+ RG+KII+ + E + K P I TS ER +IL F+ K + V S+ Sbjct: 509 HEQQRGDKIIVFADNLFALTEYAMKLRKPMIYGATSHIERTKILEAFKTSKDVNTVFLSK 568 Query: 379 VLDEGIDVPDASVGIIISG-TGSPRELVQRLGRILRP--------APGKE--RAILYELI 427 V D ID+P+A+V I IS GS R+ QRLGRILR A GKE A Y L+ Sbjct: 569 VGDNSIDIPEANVIIQISSHAGSRRQEAQRLGRILRAKGKLEDRMAGGKEEYNAFFYSLV 628 Query: 428 TPGTTEVRISSRR 440 + T E+ S++R Sbjct: 629 STDTQEMYYSTKR 641 >gb|AAG19725.1| (AE005058) putative DNA helicase; Rhl [Halobacterium sp. NRC-1] Length = 324 Score = 119 bits (295), Expect = 7e-26 Identities = 100/360 (27%), Positives = 168/360 (45%), Gaps = 56/360 (15%) Query: 104 MEIIKRLSLSTLVIVPTLALLEQWKERL----EIFGD-VGEFSGRKKELKPITVTTYDSA 158 M ++ + TLV+VP+ L QW+E L + GD +GE+ G +K ++P+T+ TY +A Sbjct: 1 MGALESVGGETLVLVPSRELATQWREELLANTSLTGDQIGEYHGGEKRVRPVTIATYQTA 60 Query: 159 YINAE---FLGDKFFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLP 215 ++ F ++ L+++DE HH+P+E R A + + +RLGLTA P R D+ + Sbjct: 61 GMDRHRHVFDDREWGLIVYDEVHHIPAEVARRSASLQ-SKHRLGLTATPVREDDKEADIY 119 Query: 216 DLIGPIVYKKAPRELMGTYLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKS 275 L+G + ++A E V ++ R++ Y Y + SG Sbjct: 120 TLVGRPIGTDWDALFDAGFVAEPE-VEIRYVPWRDDDDRY--------EYAAASG----- 165 Query: 276 LEDFQKIVMRTGVDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYN 335 R++A + AK E+ ++++H + ++ Y Sbjct: 166 ------------------------HTRRRLAAENPAKEAEIEHLVDQHGDTQALVFVDYL 201 Query: 336 ELVYEISRKFLIPAITHKTSKEERVEILRKFREGKYMAVVSSQVLDEGIDVPDASVGIII 395 I+ + P + +T R +FR G A+V S++ DEGID+PDA ++ Sbjct: 202 SQGERIAERLDAPFVNGETPHSRRETHFDQFRTGALDALVVSRIGDEGIDLPDAEFAVVA 261 Query: 396 SGT-GSPRELVQRLGRILRPAPGKERAILYELITPGTTE---VRISSRRLS--GIKKLES 449 SG GS R+ QR GR +RP +++L+ L T GT E R R LS G++ ES Sbjct: 262 SGLGGSRRQGAQRAGRTMRPG---SQSLLFVLATRGTEEEDHARSRMRHLSTKGVRVTES 318 >gb|AAB62732.1| (U77065) RepB [Dictyostelium discoideum] Length = 800 Score = 116 bits (288), Expect = 5e-25 Identities = 114/398 (28%), Positives = 185/398 (45%), Gaps = 65/398 (16%) Query: 72 LRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWK 128 +R YQE+++ + R + G+IVLP GAGK++ + + S LV+ + +EQWK Sbjct: 318 IRPYQEKSLSKMFGNGRARSGIIVLPCGAGKSLSGITAACTVKKSILVLCTSAVSVEQWK 377 Query: 129 ERLEIFGDVGE-----FSGRKKE----LKPITVTTY-----------DSAYINAEFLGDK 168 + +++ ++ E F+ KE + +T+TTY +S I E + Sbjct: 378 YQFKLWSNIEERQISKFTSDNKEKISNVAGVTITTYTMVAFGGRRSAESLKIMNEITNRE 437 Query: 169 FFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPR 228 + L++ DE H +P+ +R + ++ A +LGLTA R D L LIGP +Y+ Sbjct: 438 WGLVLLDEVHVVPAAMFRKVLTVTKAHCKLGLTATLLREDEKIQDLNFLIGPKLYEANWL 497 Query: 229 ELM-GTYLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTG 287 +L +LA V P++ E EYL +++S +K ++ T Sbjct: 498 DLQKAGFLANVSCSEVWCPMTAEFYKEYL---------INDS--------QGKKKLLYTM 540 Query: 288 VDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLI 347 NK F+A L RG+KII+ + + + ++ Sbjct: 541 NPNK-FRACEYLIR------------------FHEQRGDKIIVFSDNVYALQKYAKGLGR 581 Query: 348 PAITHKTSKEERVEILRKFR-EGKYMAVVSSQVLDEGIDVPDASVGIIISG-TGSPRELV 405 I TS ER+ IL KF+ + + S+V D ID+P+A+V I +S GS R+ Sbjct: 582 YFIYGPTSGHERMSILSKFQHDPTVRTIFISKVGDTSIDIPEATVIIQVSSHYGSRRQEA 641 Query: 406 QRLGRILRPAP---GKERAILYELITPGTTEVRISSRR 440 QRLGRILRP P G A Y L++ T E+ S++R Sbjct: 642 QRLGRILRPKPKSDGLYNAFFYSLVSKDTQEMYYSTKR 679 >gi|4557563 excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing); Excision-repair cross-complementing rodent repair deficiency,; excision repair cross-complementing rodent repair defici> >gi|119541|sp|P19447|XPB_HUMAN DNA-REPAIR PROTEIN COMPLEMENTING XP-B CELLS (XERODERMA PIGMENTOSUM GROUP B COMPLEMENTING PROTEIN) (DNA EXCISION REPAIR PROTEIN ERCC-3) (BASAL TRANSCRIPTION FACTOR 2 89 KDA SUBUNIT) (BTF2-P89) (TFIIH 89 KDA SUBUNIT) >gi|105955|pir||A35661 DNA excision repair cross-complementing protein ERCC3 - human >gi|182179|gb|AAA52396.1| (M31899) DNA repair helicase [Homo sapiens] Length = 782 Score = 113 bits (279), Expect = 6e-24 Identities = 110/399 (27%), Positives = 185/399 (45%), Gaps = 68/399 (17%) Query: 72 LRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWK 128 LR YQE+++ + R + GVIVLP GAGK++V + + LV+ + +EQWK Sbjct: 316 LRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWK 375 Query: 129 ERLEIFGDVGE-----FSGRKKELKPI---------------TVTTYDSAYINAEFLGDK 168 + +++ + + F+ K+ KPI T ++++ + + Sbjct: 376 AQFKMWSTIDDSQICRFTSDAKD-KPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQE 434 Query: 169 FFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPR 228 + L+I DE H +P++ +R + + A +LGLTA R D+ L LIGP +Y+ Sbjct: 435 WGLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWM 494 Query: 229 ELMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTG 287 EL Y+A + V P+S E EY+ +++ ++I++ T Sbjct: 495 ELQNNGYIAKVQCAEVWCPMSPEFYREYV------------------AIKTKKRILLYTM 536 Query: 288 VDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLI 347 NK F+A + L + R +KII+ + E + + Sbjct: 537 NPNK-FRACQFLIK------------------FHERRNDKIIVFADNVFALKEYAIRLNK 577 Query: 348 PAITHKTSKEERVEILRKFREG-KYMAVVSSQVLDEGIDVPDASVGIIISG-TGSPRELV 405 P I TS+ ER++IL+ F+ K + S+V D D+P+A+V I IS GS R+ Sbjct: 578 PYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEA 637 Query: 406 QRLGRILRPAPG----KERAILYELITPGTTEVRISSRR 440 QRLGR+LR G + A Y L++ T E+ S++R Sbjct: 638 QRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKR 676 >sp|P49135|XPB_MOUSE DNA-REPAIR PROTEIN COMPLEMENTING XP-B CELLS HOMOLOG (XERODERMA PIGMENTOSUM GROUP B COMPLEMENTING PROTEIN HOMOLOG) (DNA EXCISION REPAIR PROTEIN ERCC-3) (BASAL TRANSCRIPTION FACTOR 2 89 KD SUBUNIT) (BTF2-P89) (TFIIH 89 KD SUBUNIT) >gi|477426|pir||A48994 DNA excision repair cross-complementing protein ERCC3 - mouse >gi|240583|gb|AAB20614.1| (S71186) XPBC/ERCC-3=DNA repair gene [mice, Peptide, 783 aa] [Mus sp.] Length = 783 Score = 112 bits (278), Expect = 7e-24 Identities = 110/399 (27%), Positives = 184/399 (45%), Gaps = 68/399 (17%) Query: 72 LRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWK 128 LR YQE+++ + R + GVIVLP GAGK++V + + LV+ + +EQWK Sbjct: 317 LRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWK 376 Query: 129 ERLEIFGDVGE-----FSGRKKELKPI---------------TVTTYDSAYINAEFLGDK 168 + +++ + + F+ K+ KPI T ++++ + + Sbjct: 377 AQFKMWSTIDDSQICRFTSDAKD-KPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQE 435 Query: 169 FFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPR 228 + L+I DE H +P+ +R + + A +LGLTA R D+ L LIGP +Y+ Sbjct: 436 WGLMILDEVHTIPARMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWM 495 Query: 229 ELMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTG 287 EL Y+A + V P+S E EY+ +++ ++I++ T Sbjct: 496 ELQNNGYIAKVQCAEVWCPMSPEFYREYV------------------AIKTKKRILLYTM 537 Query: 288 VDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLI 347 NK F+A + L + R +KII+ + E + + Sbjct: 538 NPNK-FRACQFLIK------------------FHERRNDKIIVFADNVFALKEYAIRLNK 578 Query: 348 PAITHKTSKEERVEILRKFREG-KYMAVVSSQVLDEGIDVPDASVGIIISG-TGSPRELV 405 P I TS+ ER++IL+ F+ K + S+V D D+P+A+V I IS GS R+ Sbjct: 579 PYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEA 638 Query: 406 QRLGRILRPAPG----KERAILYELITPGTTEVRISSRR 440 QRLGR+LR G + A Y L++ T E+ S++R Sbjct: 639 QRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKR 677 >pir||T31655 DNA excision repair cross-complementing protein - sea squirt (Ciona intestinalis) >gi|1764011|emb|CAB06045.1| (Z83760) COS41.1 [Ciona intestinalis] Length = 793 Score = 110 bits (272), Expect = 4e-23 Identities = 115/443 (25%), Positives = 199/443 (43%), Gaps = 80/443 (18%) Query: 38 RDIVEFLESEGIEFE-----DYVLENALPSRVYDDVEFEL------RDYQEEAVERWM-- 84 +++VE L+ IE E +Y N + D++ +L R YQE+++ + Sbjct: 286 QEMVETLQKRCIELEYPLLAEYDFRN---DTINKDLKIDLKPTTVLRPYQEKSLRKMFGN 342 Query: 85 -REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWKERLEIFGDVGE---- 139 R + GVIVLP GAGKT+V + + +V+ + +EQW+ + +++ + Sbjct: 343 GRARSGVIVLPCGAGKTLVGVTAACTVRKRCMVLCTSGVAVEQWRSQFKMWSTADDSMIC 402 Query: 140 -FSGRKKELK---PITVTTY-----------DSAYINAEFLGDKFFLLIFDECHHLPSEA 184 F+ K+ I ++TY +S + ++ L++ DE H +P++ Sbjct: 403 RFTSDAKDRPHGCSIAISTYSMMGHSMKRSYESEKVMEWIRSQEWGLIVLDEVHTIPAKQ 462 Query: 185 YRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPRELM-GTYLAPYELVRV 243 +R + + + +LGLTA R D+ L LIGP +Y+ EL G ++A + V Sbjct: 463 FRRVLTVVQSHCKLGLTATLVREDDKISDLNFLIGPKLYEANWMELQNGGFIARVQCAEV 522 Query: 244 KVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEAR 303 P++ E EYL S+ +++++ NK F+A + L Sbjct: 523 WCPMTPEFYREYL------------------SIRSRKRLLLYVMNPNK-FRACQFLVR-- 561 Query: 304 KIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLIPAITHKTSKEERVEIL 363 R +KI++ + + E + + P I T++ ER++IL Sbjct: 562 ----------------FHERRNDKIVVFSDNVFALKEYAVRMGKPYIYGPTTQGERLQIL 605 Query: 364 RKF-REGKYMAVVSSQVLDEGIDVPDASVGIIISG-TGSPRELVQRLGRILRPAPG---- 417 + F K + S+V D ID+P A+V I +S GS R+ QRLGRILR G Sbjct: 606 QNFIHNPKVNTIFISKVGDNSIDLPAANVLIQVSSHGGSRRQEAQRLGRILRAKKGSLAE 665 Query: 418 KERAILYELITPGTTEVRISSRR 440 + A Y L++ T EV S++R Sbjct: 666 EYNAFFYSLVSQDTVEVAYSTKR 688 >sp|Q02870|XPB_DROME DNA EXCISION REPAIR PROTEIN HAYWIRE (ERCC-3 HOMOLOG PROTEIN) >gi|283659|pir||S26719 ERCC3 protein - fruit fly (Drosophila melanogaster) >gi|11079|emb|CAA48386.1| (X68309) ERCC3 [Drosophila melanogaster] Length = 802 Score = 109 bits (270), Expect = 6e-23 Identities = 112/401 (27%), Positives = 183/401 (44%), Gaps = 72/401 (17%) Query: 72 LRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWK 128 LR YQE+++ + R + GVIVLP GAGK++V + + LV+ + +EQWK Sbjct: 336 LRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTACCTVRKRALVLCNSGVSVEQWK 395 Query: 129 ERLEIFGDVGE-----FSGRKKELKP----ITVTTYD----------SAYINAEFLGD-K 168 ++ +++ + F+ K+ KP I VTTY A +L + + Sbjct: 396 QQFKMWSTADDSMICRFTSEAKD-KPMGCGILVTTYSMITHTQKRSWEAEQTMRWLQEQE 454 Query: 169 FFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPR 228 + +++ DE H +P++ +R + + + +LGLTA R D+ L LIGP +Y+ Sbjct: 455 WGIMVLDEVHTIPAKMFRRVLTIVQSHCKLGLTATLLREDDKIADLNFLIGPKLYEANWL 514 Query: 229 ELMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTG 287 EL Y+A + V P+S E EYL K K+ L Sbjct: 515 ELQKKGYIARVQCAEVWCPMSPEFYREYLT-TKTSKKML--------------------- 552 Query: 288 VDNKAFKALRALEEARKIALGSKAKIEELRKILERH--RGEKIIISTRYNELVYEISRKF 345 + + + +K + +++ H RG+K I+ + + + K Sbjct: 553 -----------------LYVMNPSKFRSCQFLIKYHEQRGDKTIVFSDNVFALKHYAIKM 595 Query: 346 LIPAITHKTSKEERVEILRKFR-EGKYMAVVSSQVLDEGIDVPDASVGIIISG-TGSPRE 403 P I TS+ ER++IL+ F+ K + S+V D D+P+A+V I IS GS R+ Sbjct: 596 NKPFIYGPTSQNERIQILQNFKFNSKVNTIFVSKVADTSFDLPEANVLIQISSHGGSRRQ 655 Query: 404 LVQRLGRILRPAPG----KERAILYELITPGTTEVRISSRR 440 QRLGRILR G + A Y L++ T E+ S +R Sbjct: 656 EAQRLGRILRAKKGAIAEEYNAFFYTLVSQDTMEMSYSRKR 696 >gb|AAF50150.1| (AE003547) hay gene product [Drosophila melanogaster] Length = 798 Score = 109 bits (270), Expect = 6e-23 Identities = 112/401 (27%), Positives = 183/401 (44%), Gaps = 72/401 (17%) Query: 72 LRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWK 128 LR YQE+++ + R + GVIVLP GAGK++V + + LV+ + +EQWK Sbjct: 332 LRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTACCTVRKRALVLCNSGVSVEQWK 391 Query: 129 ERLEIFGDVGE-----FSGRKKELKP----ITVTTYD----------SAYINAEFLGD-K 168 ++ +++ + F+ K+ KP I VTTY A +L + + Sbjct: 392 QQFKMWSTADDSMICRFTSEAKD-KPMGCGILVTTYSMITHTQKRSWEAEQTMRWLQEQE 450 Query: 169 FFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPR 228 + +++ DE H +P++ +R + + + +LGLTA R D+ L LIGP +Y+ Sbjct: 451 WGIMVLDEVHTIPAKMFRRVLTIVQSHCKLGLTATLLREDDKIADLNFLIGPKLYEANWL 510 Query: 229 ELMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTG 287 EL Y+A + V P+S E EYL K K+ L Sbjct: 511 ELQKKGYIARVQCAEVWCPMSPEFYREYLT-TKTSKKML--------------------- 548 Query: 288 VDNKAFKALRALEEARKIALGSKAKIEELRKILERH--RGEKIIISTRYNELVYEISRKF 345 + + + +K + +++ H RG+K I+ + + + K Sbjct: 549 -----------------LYVMNPSKFRSCQFLIKYHEQRGDKTIVFSDNVFALKHYAIKM 591 Query: 346 LIPAITHKTSKEERVEILRKFR-EGKYMAVVSSQVLDEGIDVPDASVGIIISG-TGSPRE 403 P I TS+ ER++IL+ F+ K + S+V D D+P+A+V I IS GS R+ Sbjct: 592 NKPFIYGPTSQNERIQILQNFKFNSKVNTIFVSKVADTSFDLPEANVLIQISSHGGSRRQ 651 Query: 404 LVQRLGRILRPAPG----KERAILYELITPGTTEVRISSRR 440 QRLGRILR G + A Y L++ T E+ S +R Sbjct: 652 EAQRLGRILRAKKGAIAEEYNAFFYTLVSQDTMEMSYSRKR 692 >pir||A44223 DNA excision repair cross-complementing protein ERCC3 - fruit fly (Drosophila melanogaster) Length = 802 Score = 109 bits (269), Expect = 8e-23 Identities = 111/399 (27%), Positives = 177/399 (43%), Gaps = 69/399 (17%) Query: 72 LRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWK 128 LR YQE+++ + R + GVIVLP GAGK++V + + LV+ + +EQWK Sbjct: 337 LRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTACCTVRKRALVLCNSGVSVEQWK 396 Query: 129 ERLEIFGDVGE-----FSGRKKELKP----ITVTTYD----------SAYINAEFLGD-K 168 ++ +++ + F+ K+ KP I VTTY A +L + + Sbjct: 397 QQFKMWSTADDSMICRFTSEAKD-KPMGCGILVTTYSMITHTQKRSWEAEQTMRWLQEQE 455 Query: 169 FFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPR 228 + +++ DE H +P++ +R + + + +LGLTA R D+ L LIGP +Y+ Sbjct: 456 WGIMVLDEVHTIPAKMFRRVLTIVQSHCKLGLTATLLREDDKIADLNFLIGPKLYEANWL 515 Query: 229 ELMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTG 287 EL Y+A + V P+S E EYL K L + + +S + K Sbjct: 516 ELQKKGYIARVQCAEVWCPMSPEFYREYLTTKTSKKMLLYVNPSKFRSCQFLIK------ 569 Query: 288 VDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLI 347 RG+K I+ + + + K Sbjct: 570 --------------------------------YHEQRGDKTIVFSDNVFALKHYAIKMNK 597 Query: 348 PAITHKTSKEERVEILRKFR-EGKYMAVVSSQVLDEGIDVPDASVGIIISG-TGSPRELV 405 P I TS+ ER++IL+ F+ K + S+V D D+P+A+V I IS GS R+ Sbjct: 598 PFIYGPTSQNERIQILQNFKFNSKVNTIFVSKVADTSFDLPEANVLIQISSHGGSRRQEA 657 Query: 406 QRLGRILRPAPG----KERAILYELITPGTTEVRISSRR 440 QRLGRILR G + A Y L++ T E+ S +R Sbjct: 658 QRLGRILRAKKGAIAEEYNAFFYTLVSQDTMEMSYSRKR 696 >emb|CAA76655.1| (Y17148) XPB protein [Geodia cydonium] Length = 810 Score = 109 bits (269), Expect = 8e-23 Identities = 108/403 (26%), Positives = 190/403 (46%), Gaps = 75/403 (18%) Query: 72 LRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWK 128 LR YQE+++ + R + GVIVLP GAGKT+V + + LV+ + +EQW+ Sbjct: 335 LRPYQEKSLRKMFGNGRARSGVIVLPCGAGKTLVGVTAACTVRKRCLVLCTSAVAVEQWR 394 Query: 129 ERLEIFGDVGE-----FSGRKKELKP-----ITVTTY-----------DSAYINAEFLGD 167 + +++ + E F+ K+ KP + ++TY DS + Sbjct: 395 SQFKLWSTIDERLVCRFTSDAKD-KPSPNTAVAISTYAMVAYTQKRAWDSQQMMNFLQQQ 453 Query: 168 KFFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAP 227 ++ L+I DE +P++ +R + A +LGLTA R D+ L LIGP +Y+ Sbjct: 454 EWGLMILDEVQTIPADKFRRTLAVVQAHTKLGLTATLVREDDKIQDLNFLIGPKLYEANW 513 Query: 228 RELMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRT 286 EL ++A + V P++ E +EYLK ++ +K ++ Sbjct: 514 MELQNNGFIAKVQCAEVWCPMTPEFYSEYLK------------------IKTRRKKLLYV 555 Query: 287 GVDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEI---SR 343 NK F+A + L + + R +KIII ++++V+ + ++ Sbjct: 556 MNPNK-FRACQFLMKHHE------------------QRNDKIII---FSDVVFSLRTYAK 593 Query: 344 KFLIPAITHKTSKEERVEILRKFREGKYM-AVVSSQVLDEGIDVPDASVGIIISG-TGSP 401 + P I +T+++ER+++L+ F+ + ++ S+V D D+PDA+V IS GS Sbjct: 594 RLNKPFIDGQTNQQERMKVLQNFKHNPLVNTILISKVGDNSFDLPDANVLWKISAHGGSR 653 Query: 402 RELVQRLGRILR----PAPGKERAILYELITPGTTEVRISSRR 440 R+ QRLG ILR + A Y L++ T E+ S++R Sbjct: 654 RQEAQRLGGILRAKKDSVSEEYNAFFYSLVSQDTEEMHFSTKR 696 >gb|AAA34942.1| (L01414) DNA helicase [Saccharomyces cerevisiae] Length = 843 Score = 108 bits (267), Expect = 1e-22 Identities = 108/404 (26%), Positives = 181/404 (44%), Gaps = 76/404 (18%) Query: 71 ELRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQW 127 ++R YQE+++ + R + G+IVLP GAGKT+V + + S +V+ + + QW Sbjct: 361 QIRPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLVGITAACTIKKSVIVLCTSSVSVMQW 420 Query: 128 KERLEIF-----GDVGEFSGRKKEL----KPITVTTY-----------DSAYINAEFLGD 167 +++ + + F+ KE+ + V+TY DS + G Sbjct: 421 RQQFLQWCTLQPENCAVFTSDNKEMFQTESGLVVSTYSMVANTRNRSHDSQKVMDFLTGR 480 Query: 168 KFFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAP 227 ++ +I DE H +P+ +R + AA +LGLTA R D+ L LIGP +Y+ Sbjct: 481 EWGFIILDEVHVVPAAMFRRVVSTIAAHAKLGLTATLVREDDKIGDLNFLIGPKLYEANW 540 Query: 228 REL-MGTYLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRT 286 EL ++A + V P++ E EYL+ Sbjct: 541 MELSQKGHIANVQCAEVWCPMTAEFYQEYLR----------------------------- 571 Query: 287 GVDNKAFKALRALEEARK---IALGSKAKIEELRKILERH--RGEKIIISTRYNELVYEI 341 E ARK + + + K + + +++ H RG+KII+ + + E Sbjct: 572 -------------ETARKRMLLYIMNPTKFQACQFLIQYHERRGDKIIVFSDNVYALQEY 618 Query: 342 SRKFLIPAITHKTSKEERVEILRKFR-EGKYMAVVSSQVLDEGIDVPDASVGIIISG-TG 399 + K P I T ++ER+ IL+ F+ + + S+V D ID+P+A+ I IS G Sbjct: 619 ALKMGKPFIYGSTPQQERMNILQNFQYNDQINTIFLSKVGDTSIDLPEATCLIQISSHYG 678 Query: 400 SPRELVQRLGRILRPAPGKE---RAILYELITPGTTEVRISSRR 440 S R+ QRLGRILR + A Y L++ T E+ S++R Sbjct: 679 SRRQEAQRLGRILRAKRRNDEGFNAFFYSLVSKDTQEMYYSTKR 722 >gi|6322048 DNA helicase homolog; homolog of human XPBC, ERCC3; Ssl2p [Saccharomyces cerevisiae] >gi|267033|sp|Q00578|RA25_YEAST DNA REPAIR HELICASE RAD25 >gi|320659|pir||S31272 DNA excision repair cross-complementing protein ERCC3 [validated] - yeast (Saccharomyces cerevisiae) >gi|172724|gb|AAA35102.1| (M94176) encodes human ERCC-3 homologue [Saccharomyces cerevisiae] >gi|557780|emb|CAA86135.1| (Z38059) DNA repair helicase [Saccharomyces cerevisiae] Length = 843 Score = 108 bits (267), Expect = 1e-22 Identities = 108/404 (26%), Positives = 181/404 (44%), Gaps = 76/404 (18%) Query: 71 ELRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQW 127 ++R YQE+++ + R + G+IVLP GAGKT+V + + S +V+ + + QW Sbjct: 361 QIRPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLVGITAACTIKKSVIVLCTSSVSVMQW 420 Query: 128 KERLEIF-----GDVGEFSGRKKEL----KPITVTTY-----------DSAYINAEFLGD 167 +++ + + F+ KE+ + V+TY DS + G Sbjct: 421 RQQFLQWCTLQPENCAVFTSDNKEMFQTESGLVVSTYSMVANTRNRSHDSQKVMDFLTGR 480 Query: 168 KFFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAP 227 ++ +I DE H +P+ +R + AA +LGLTA R D+ L LIGP +Y+ Sbjct: 481 EWGFIILDEVHVVPAAMFRRVVSTIAAHAKLGLTATLVREDDKIGDLNFLIGPKLYEANW 540 Query: 228 REL-MGTYLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRT 286 EL ++A + V P++ E EYL+ Sbjct: 541 MELSQKGHIANVQCAEVWCPMTAEFYQEYLR----------------------------- 571 Query: 287 GVDNKAFKALRALEEARK---IALGSKAKIEELRKILERH--RGEKIIISTRYNELVYEI 341 E ARK + + + K + + +++ H RG+KII+ + + E Sbjct: 572 -------------ETARKRMLLYIMNPTKFQACQFLIQYHERRGDKIIVFSDNVYALQEY 618 Query: 342 SRKFLIPAITHKTSKEERVEILRKFR-EGKYMAVVSSQVLDEGIDVPDASVGIIISG-TG 399 + K P I T ++ER+ IL+ F+ + + S+V D ID+P+A+ I IS G Sbjct: 619 ALKMGKPFIYGSTPQQERMNILQNFQYNDQINTIFLSKVGDTSIDLPEATCLIQISSHYG 678 Query: 400 SPRELVQRLGRILRPAPGKE---RAILYELITPGTTEVRISSRR 440 S R+ QRLGRILR + A Y L++ T E+ S++R Sbjct: 679 SRRQEAQRLGRILRAKRRNDEGFNAFFYSLVSKDTQEMYYSTKR 722 >gb|AAA74931.1| (L02965) helicase [Drosophila melanogaster] Length = 801 Score = 105 bits (259), Expect = 1e-21 Identities = 110/399 (27%), Positives = 176/399 (43%), Gaps = 69/399 (17%) Query: 72 LRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWK 128 LR YQE+++ + R + GVIVLP GAGK++V + + LV+ + +EQWK Sbjct: 336 LRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTACCTVRKRALVLCNSGVSVEQWK 395 Query: 129 ERLEIFGDVGE-----FSGRKKELKP----ITVTTYD----------SAYINAEFLGD-K 168 ++ +++ + F+ K+ KP I VTTY A +L + + Sbjct: 396 QQFKMWSTADDSMICRFTSEAKD-KPMGCGILVTTYSMITHTQKRSWEAEQTMRWLQEQE 454 Query: 169 FFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPR 228 + +++ DE H +P++ +R + + + +LGLTA R D+ L LIGP +Y+ Sbjct: 455 WGIMVLDEVHTIPAKMFRRVLTIVQSHCKLGLTATLLREDDKIADLNFLIGPKLYEANWL 514 Query: 229 ELMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTG 287 EL Y+A + V P+S E EYL K L + + +S + K Sbjct: 515 ELQKKGYIARCQCAEVWCPMSPEFYREYLTTKTSKKMLLYVNPSKFRSCQFLIK------ 568 Query: 288 VDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLI 347 RG+K I+ + + + K Sbjct: 569 --------------------------------YHEQRGDKTIVFSDNVFALKHYAIKMNK 596 Query: 348 PAITHKTSKEERVEILRKFR-EGKYMAVVSSQVLDEGIDVPDASVGIIISG-TGSPRELV 405 P I TS+ ER++IL+ F+ K + S+V D D+P+A+V I IS GS R+ Sbjct: 597 PFIYGPTSQNERIQILQNFKFNSKVNTIFVSKVADTSFDLPEANVLIQISSHGGSRRQEA 656 Query: 406 QRLGRILRPAPG----KERAILYELITPGTTEVRISSRR 440 QRL RILR G + A Y L++ T E+ S +R Sbjct: 657 QRLVRILRAKKGAIAEEYNAFFYTLVSQDTMEMSYSRKR 695 >pir||T37821 probable dna repair helicase - fission yeast (Schizosaccharomyces pombe) >gi|2370478|emb|CAB11506.1| (Z98849) putative dna repair helicase [Schizosaccharomyces pombe] Length = 804 Score = 102 bits (253), Expect = 6e-21 Identities = 108/403 (26%), Positives = 185/403 (45%), Gaps = 74/403 (18%) Query: 71 ELRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQW 127 ++R YQE+++ + R + G+IVLP GAGKT+V + + S +V+ + + QW Sbjct: 323 QIRPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLVGITAACTIKKSVIVLCTSSVSVMQW 382 Query: 128 KERLEIFGDV-----GEFSGRKKEL----KPITVTTY-----------DSAYINAEFLGD 167 +++ + ++ F+ KE + V+TY DS + G Sbjct: 383 RQQFLQWSNIKPDHIAVFTADHKERFHSEAGVVVSTYSMVANTRNRSYDSQKMMDFLTGR 442 Query: 168 KFFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAP 227 ++ ++ DE H +P+ +R + AA +LGLTA R D+ D L LIGP +Y+ Sbjct: 443 EWGFILLDEVHVVPAAMFRRVVTTIAAHTKLGLTATLVREDDKIDDLNFLIGPKMYEANW 502 Query: 228 REL-MGTYLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRT 286 +L ++A + V ++ E EYL+ E+ +K ++ Sbjct: 503 MDLAQKGHIAKVQCAEVWCAMTTEFYNEYLR-------------------ENSRKRMLLY 543 Query: 287 GVDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFL 346 ++ K F+A + L + RG+KII+ +++ VY + R + Sbjct: 544 IMNPKKFQACQFLID------------------YHEKRGDKIIV---FSDNVYAL-RAYA 581 Query: 347 IPA----ITHKTSKEERVEILRKFREGKYM-AVVSSQVLDEGIDVPDASVGIIISG-TGS 400 I I T ++ER+ IL F+ + + + S+V D ID+P+A+ I IS GS Sbjct: 582 IKLGKYFIYGGTPQQERMRILENFQYNELVNTIFLSKVGDTSIDLPEATCLIQISSHYGS 641 Query: 401 PRELVQRLGRILRPAPGKE---RAILYELITPGTTEVRISSRR 440 R+ QRLGRILR + A Y L++ T E+ SS+R Sbjct: 642 RRQEAQRLGRILRAKRRNDEGFNAFFYSLVSKDTQEMYYSSKR 684 >gi|11429283 excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) [Homo sapiens] Length = 580 Score = 78.4 bits (190), Expect = 2e-13 Identities = 81/320 (25%), Positives = 143/320 (44%), Gaps = 62/320 (19%) Query: 72 LRDYQEEAVERWM---REKRGVIVLPTGAGKTIVAMEIIKRLSLSTLVIVPTLALLEQWK 128 LR YQE+++ + R + GVIVLP GAGK++V + + LV+ + +EQWK Sbjct: 145 LRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWK 204 Query: 129 ERLEIFGDVGE-----FSGRKKELKPI---------------TVTTYDSAYINAEFLGDK 168 + +++ + + F+ K+ KPI T ++++ + + Sbjct: 205 AQFKMWSTIDDSQICRFTSDAKD-KPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQE 263 Query: 169 FFLLIFDECHHLPSEAYRNIAQMSAAPYRLGLTAFPERADNLHDLLPDLIGPIVYKKAPR 228 + L+I DE H +P++ +R + + A +LGLTA R D+ L LIGP +Y+ Sbjct: 264 WGLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWM 323 Query: 229 ELMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTG 287 EL Y+A + V P+S E EY+ +++ ++I++ T Sbjct: 324 ELQNNGYIAKVQCAEVWCPMSPEFYREYV------------------AIKTKKRILLYTM 365 Query: 288 VDNKAFKALRALEEARKIALGSKAKIEELRKILERHRGEKIIISTRYNELVYEISRKFLI 347 NK F+A + L + R +KII+ + E + + Sbjct: 366 NPNK-FRACQFLIK------------------FHERRNDKIIVFADNVFALKEYAIRLNK 406 Query: 348 PAITHKTSKEERVEILRKFR 367 P I TS+ ER++IL+ F+ Sbjct: 407 PYIYGPTSQGERMQILQNFK 426 >emb|CAA67095.1| (X98455) SNF [Bacillus cereus] Length = 1064 Score = 71.4 bits (172), Expect = 2e-11 Identities = 106/430 (24%), Positives = 187/430 (42%), Gaps = 79/430 (18%) Query: 72 LRDYQEEAVERWMREKR-----GVIVLPTGAGKTIVAMEII-------KRLSLSTLVIVP 119 +R+YQ E WM+ G++ G GKT+ ++ I + L LV+ P Sbjct: 613 MREYQVYGFE-WMKTLAYYRFGGILADDMGLGKTLQSIAYIDSVLPEIREKKLPILVVSP 671 Query: 120 TLALLEQWKERLEIFGDV-------GEFSGRKKELKPIT-----VTTYDSAYINAEFLGD 167 + +L+ W L+ F G + R+K LK + +T+Y + Sbjct: 672 S-SLVYNWFSELKKFAPHIRAVIADGNQTERRKILKDVAEFDVVITSYPLLRRDVRSYAR 730 Query: 168 KFFLLIFDECHHLPSEAYRNIAQMSA-------APYRLGLTAFP------ERADNLHDLL 214 F L DE ++A++N +A A YR GLT P E H + Sbjct: 731 PFHTLFLDE-----AQAFKNPTTQTARAVKTIQAEYRFGLTGTPVENSLEELWSIFHVVF 785 Query: 215 PDLI-GPIVYKKAPRELMGTYLAPYELVRVKVPLSRE--ERAEYLK-------HYKVFKR 264 P+L+ G + RE + + P+ L R+K + +E ++ E+L+ +++ Sbjct: 786 PELLPGRKEFGDLRREDIANAVKPFVLRRLKEDVLQELPDKIEHLQSSELLPDQKRLYAA 845 Query: 265 YLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKIA----------LGSKAKIE 314 YL++ LR ++L+ K +R NK + L L R+I GS AK+E Sbjct: 846 YLAK--LREETLKHLDKDTLRK---NK-IRILAGLTRLRQICNHPALFVDDYKGSSAKLE 899 Query: 315 ELRKILE--RHRGEKIIISTRYNELVYEISRKFLIPAITH-----KTSKEERVEILRKFR 367 +L ILE R G++I+I +++ +++ I R+ AI + T +ERVE+ +F Sbjct: 900 QLLDILEECRSTGKRILIFSQFTKMLSIIGRELNRQAIPYFYLDGNTPSQERVELCNRFN 959 Query: 368 EGK-YMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRPAPGKERAILYEL 426 EG+ + ++S + G+++ A I+ +P Q R R K + +L Sbjct: 960 EGEGDLFLISLKAGGTGLNLTGADTVILYDLWWNPAVEQQAADRAYRMGQ-KNTVQVIKL 1018 Query: 427 ITPGTTEVRI 436 + GT E ++ Sbjct: 1019 VAHGTIEEKM 1028 >gi|6320539 Ydr332wp [Saccharomyces cerevisiae] >gi|2131433|pir||S59797 hypothetical protein YDR332w - yeast (Saccharomyces cerevisiae) >gi|914990|gb|AAB64767.1| (U32517) Ydr332wp [Saccharomyces cerevisiae] Length = 689 Score = 71.4 bits (172), Expect = 2e-11 Identities = 89/404 (22%), Positives = 180/404 (44%), Gaps = 64/404 (15%) Query: 72 LRDYQEEAVERWMRE-----KRGVIVLPTGAGKTIVAMEIIKRL----------SLSTLV 116 LRDYQ++A++ + KR + L TG GKT++ +I +L + +L+ Sbjct: 33 LRDYQQDAIDACVNSIRQGTKRIGVSLATGGGKTVIFSNLINQLRQNYFKERQGNFKSLI 92 Query: 117 IV-------PTLALLEQWKERLEIFGDVGEFSGRKKELKPITVTTYDSAYINAEFLGDKF 169 +V A L++ L++ ++G++ ++ I + ++ + Sbjct: 93 LVHRRELALQATATLKKIFPDLKVHIEMGKYDCDIEDSDVIVASVQTLIRRLHKYDTNSV 152 Query: 170 FLLIFDECHHLPSEAYRNIA---QMSAAPYRL---GLTAFPERADNLHDLLPDLIGPIVY 223 L+I DE HH + +YR+I + S A ++ G +A ERAD L ++ IVY Sbjct: 153 NLIIIDEAHHSVANSYRSILDHFKASTAETKIPVIGFSATFERADKR--ALSMVMDKIVY 210 Query: 224 KKAPRELMGT-YLAPYELVRVKVPLSREERAEYLKHYKVFKRYLSESGLRIKSLEDFQKI 282 + E++ +L + VK+ + +++ LS + + ++ ++ Sbjct: 211 HRGILEMIDDKWLCEAKFTSVKIEADLSDVKSTADDFQLAP--LSS----LMNTKEINEV 264 Query: 283 VMRTGVDNKAFKALRALEEARKIALG-SKAKIEELRKILERHRGEKIIISTRYNELVYEI 341 +++T + K K+L++ + G KA ++ L K+ + + I+T Y Sbjct: 265 ILKTYLHKKQEKSLKST-----LLFGVDKAHVQSLHKLFKDNG-----INTDY------- 307 Query: 342 SRKFLIPAITHKTSKEERVEILRKFREGKYMAVVSSQVLDEGIDVPDASVGIIISGTGSP 401 +T T + ER I++KF+ G+ +++ + EG D+P+ ++ T S Sbjct: 308 --------VTSDTKQIERDNIIQKFKNGETEVLMNCGIFTEGTDMPNIDCILLCRPTKSR 359 Query: 402 RELVQRLGRILRPAPGKERAILYELITPGTTEVRISSRRLSGIK 445 L+Q +GR LR K+ + + I + V +S+ L GI+ Sbjct: 360 SLLIQMIGRGLRLHHSKDHCHIIDFIGASSVGV-VSAPTLLGIR 402 >pir||E71481 probable swf/snf helicase - Chlamydia trachomatis (serotype D, strain UW3/Cx) >gi|3329163|gb|AAC68303.1| (AE001341) SWF/SNF family helicase [Chlamydia trachomatis] Length = 1163 Score = 70.6 bits (170), Expect = 3e-11 Identities = 115/462 (24%), Positives = 197/462 (41%), Gaps = 79/462 (17%) Query: 64 VYDDVEFELRDYQEEAVERWMREKR-----GVIVLPTGAGKTIVAMEIIKRLSLS----- 113 V ++ LR YQ+E V W+ R G++ G GKT+ + + + L Sbjct: 691 VPSQIQATLRGYQKEGVH-WLERLRKMHLNGILADDMGLGKTLQTIIAVTQSRLEKGGGC 749 Query: 114 TLVIVPTLALLEQWKERLEIFGDV-------GEFSGRKKELKP-----ITVTTYDSAYIN 161 +L+I PT +L+ WKE F G S R+K+L + +T+Y+ + Sbjct: 750 SLIICPT-SLVYNWKEEFRKFNPEFKTLVVDGIPSQRRKQLASLEEYDVAITSYNLLQKD 808 Query: 162 AEFLGDKFF-LLIFDECHHLPSEAYRNI--AQMSAAPYRLGLTAFP-----ERADNLHD- 212 + D F ++ DE HH+ + RN +M A +RL LT P E +L D Sbjct: 809 IDIYKDFLFDYVVLDEAHHIKNRTTRNAKSVKMIRACHRLILTGTPIENSLEELWSLFDF 868 Query: 213 LLPDL-------------IGPIVYKKAPR-ELMGTYLAPYELVRVKVPLSRE----ERAE 254 L+P L IG + KA E + +AP+ L R+K + + Sbjct: 869 LMPGLLSSYDRFVGKYIRIGNYMGNKADNVEALRRKVAPFILRRMKEDVLEDLPPVSEIL 928 Query: 255 YLKHYKVFKRYLSESGLRIKSLEDFQKIVMRTGVDNKAFKALRALEEARKIAL------- 307 Y H +R L +S + ++ ++V + G + L L ++I Sbjct: 929 YHCHLTESQRELYQS-YAASARQELSRLVKQEGFERIHIHVLATLTRLKQICCHPAIFAK 987 Query: 308 -----GSKAKIEELRKILER--HRGEKIIISTRYNELVYEISRKFL----IPAITHKTSK 356 G AK + L +L G K ++ ++Y +++ I R+ L IP + S Sbjct: 988 DTPEPGDSAKYDMLMDLLSSLVDSGHKTVVFSQYTKML-GIIRQDLEAKGIPFVYLDGST 1046 Query: 357 EERVEILRKFRE--GKYMAVVSSQVLDEGIDVPDASVGIIISGTGSPRELVQRLGRILRP 414 + R+EI+++F E G + +VS + G+++ A I +P Q R+ R Sbjct: 1047 KNRLEIVQQFNEDPGLLVFLVSLKAGGTGLNLVGADTVIHYDMWWNPAVENQATDRVHR- 1105 Query: 415 APGKERAI-LYELITPGTTEVRISS---RRLSGIKKLESLDD 452 G+ R++ Y+L+T T E +I S R+ +KK+ + DD Sbjct: 1106 -IGQSRSVSSYKLVTLNTIEEKILSLQNRKKGLVKKVINSDD 1146 >emb|CAB93078.1| (AL357432) putative helicase (fragment) [Streptomyces coelicolor A3(2)] Length = 135 Score = 69.1 bits (166), Expect = 1e-10 Identities = 38/114 (33%), Positives = 65/114 (56%), Gaps = 1/114 (0%) Query: 328 IIISTRYNELVYEISRKFLIPAITHKTSKEERVEILRKFREGKYMAVVSSQVLDEGIDVP 387 I++ +Y + + E+ P I +TS +R ++ FR+G+ +V S+V + ID+P Sbjct: 1 ILVIGQYIDQLDELGEHLGAPVIKGETSNAQREKLFESFRQGEISVLVVSKVANFSIDLP 60 Query: 388 DASVGIIISGT-GSPRELVQRLGRILRPAPGKERAILYELITPGTTEVRISSRR 440 +A+V I +SGT GS +E QRLGR+LRP +A Y ++ T + ++ R Sbjct: 61 EATVAIQVSGTFGSRQEEAQRLGRVLRPKADGHQAHFYSVVARDTLDQDFAAHR 114 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.320 0.140 0.395 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 160720877 Number of Sequences: 2977 Number of extensions: 6793279 Number of successful extensions: 22421 Number of sequences better than 1.0e-10: 35 Number of HSP's better than 0.0 without gapping: 9 Number of HSP's successfully gapped in prelim test: 26 Number of HSP's that attempted gapping in prelim test: 22315 Number of HSP's gapped (non-prelim): 58 length of query: 453 length of database: 189,106,746 effective HSP length: 57 effective length of query: 396 effective length of database: 154,992,987 effective search space: 61377222852 effective search space used: 61377222852 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.8 bits) S2: 166 (69.1 bits)