BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1324 (PAB1324) DE:STOMATIN-LIKE PROTEIN
         (299 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||F75003 stomatin-like protein PAB1324 - Pyrococcus abyssi (s...   574  e-163
pir||A71159 probable membrane protein - Pyrococcus horikoshii >g...   536  e-152
pir||E72322 conserved hypothetical protein - Thermotoga maritima...   306  2e-82
sp|O26788|Y692_METTH HYPOTHETICAL PROTEIN MTH692 >gi|7447611|pir...   292  4e-78
pir||D75311 conserved hypothetical protein - Deinococcus radiodu...   244  8e-64
emb|CAB94650.1| (AL359215) putative secreted protein. [Streptomy...   238  4e-62
sp|P71768|YE88_MYCTU HYPOTHETICAL 41.2 KDA PROTEIN RV1488 >gi|74...   236  2e-61
pir||T36857 conserved hypothetical protein SCI5.04c - Streptomyc...   235  4e-61
gb|AAF09169.1|AF065260_1 (AF065260) HflC homolog [Clostridium di...   227  1e-58
gi|10955528 77 pct identical to sp:YBBK_ECOLI[hypothetical 33kd ...   219  2e-56
gb|AAG18899.1| (AE004992) bifunctional short chain isoprenyl dip...   217  1e-55
sp|P77367|YBBK_ECOLI HYPOTHETICAL 33.7 KD PROTEIN IN USHA-TESA I...   215  6e-55
pir||F82256 conserved hypothetical protein VC0976 [imported] - V...   214  1e-54
sp|Q58237|Y827_METJA HYPOTHETICAL PROTEIN MJ0827 >gi|2129105|pir...   206  3e-52
pir||A82838 conserved hypothetical protein XF0185 [imported] - X...   202  4e-51
sp|P72655|YB28_SYNY3 HYPOTHETICAL 35.7 KD PROTEIN SLR1128 >gi|74...   202  4e-51
gb|AAK42367.1| Erythrocyte band 7 membrane protein homolog [Sulf...   196  2e-49
gb|AAF42660.1|AF226511_1 (AF226511) membrane protein GNA1220 [Ne...   192  3e-48
pir||F81107 stomatin/Mec-2 family protein NMB1220 [imported] - N...   192  4e-48
gb|AAF44771.1|AF235154_1 (AF235154) GNA1220 [Neisseria gonorrhoe...   192  4e-48
pir||H81907 probable periplasmic protein NMA1382 [imported] - Ne...   192  5e-48
gb|AAF42676.1|AF226528_1 (AF226528) membrane protein GNA1220 [Ne...   192  5e-48
sp|O59180|YF11_PYRHO HYPOTHETICAL PROTEIN PH1511 >gi|7447604|pir...   191  7e-48
gb|AAC46209.1| (AF002133) MAV266 [Mycobacterium avium]                191  7e-48
gb|AAF42668.1|AF226519_1 (AF226519) membrane protein GNA1220 [Ne...   191  7e-48
pir||B75107 stomatin-like protein PAB1933 - Pyrococcus abyssi (s...   191  9e-48
gb|AAF42663.1|AF226514_1 (AF226514) membrane protein GNA1220 [Ne...   190  1e-47
gb|AAF42675.1|AF226527_1 (AF226527) membrane protein GNA1220 [Ne...   190  2e-47
pir||D72522 probable erythrocyte band 7 integral membrane protei...   190  2e-47
gi|11499015 membrane protein [Archaeoglobus fulgidus] >gi|664798...   189  3e-47
pir||F70378 erythrocyte band 7 homolog - Aquifex aeolicus >gi|29...   183  2e-45
pir||T39599 conserved hypothetical protein SPBC16G5.07c - fissio...   183  3e-45
pir||B71689 hypothetical protein RP328 - Rickettsia prowazekii >...   182  3e-45
gi|7305503 stomatin-like protein 2 [Homo sapiens] >gi|6456118|gb...   179  4e-44
gi|11429564 stomatin-like protein 2 [Homo sapiens]                    179  4e-44
pir||A83590 probable stomatin-like protein PA0452 [imported] - P...   178  9e-44
gb|AAF29073.1|AF161458_1 (AF161458) HSPC108 [Homo sapiens]            177  1e-43
gb|AAF47110.1| (AE003462) CG2970 gene product [Drosophila melano...   175  4e-43
pir||T21562 hypothetical protein F30A10.5 - Caenorhabditis elega...   173  2e-42
gb|AAF68388.1|AF236372_1 (AF236372) stomatin-like protein [Zea m...   171  9e-42
pir||T02246 hypothetical protein P1.11659_4 - human >gi|2984585|...   169  3e-41
pir||T18493 hypothetical protein C0800w - malaria parasite (Plas...   168  1e-40
pir||T05863 hypothetical protein T29A15.70 - Arabidopsis thalian...   168  1e-40
dbj|BAA97132.1| (AB018115) contains similarity to stomatin like ...   167  1e-40
pir||G69104 stomatin-like protein - Methanobacterium thermoautot...   161  1e-38
gb|AAC64873.1| (AF034831) stomatin like protein [Rhizobium etli]      159  3e-38
emb|CAC12423.1| (AL445067) membrane protein 7, erythrocyte (huma...   155  7e-37
gb|AAF48927.1| (AE003511) CG7633 gene product [Drosophila melano...   153  2e-36
gb|AAF48928.1| (AE003511) CG7635 gene product [Drosophila melano...   150  2e-35
sp|Q27433|MEC2_CAEEL MECHANOSENSORY PROTEIN 2 >gi|2133486|pir||S...   148  7e-35
emb|CAA73876.1| (Y13473) stomatin [Danio rerio]                       147  2e-34
emb|CAB76415.1| (Z66565) contains similarity to Pfam domain: PF0...   146  4e-34
pir||T34691 hypothetical protein SC1B5.13c SC1B5.13c - Streptomy...   145  8e-34
sp|Q19200|STO1_CAEEL STO-1 PROTEIN >gi|7447613|pir||T15971 hypot...   141  7e-33
sp|Q22165|STO4_CAEEL STO-4 PROTEIN                                    141  9e-33
gb|AAF14646.1|AF163772_6 (AF163772) 7138.6 [Leishmania major]         141  9e-33
gb|AAF54744.1| (AE003694) CG17424 gene product [Drosophila melan...   141  1e-32
sp|Q21190|UNC1_CAEEL UNC-1 PROTEIN >gi|7494583|pir||T34324 eryth...   140  2e-32
pir||T27365 hypothetical protein Y71H9A.2 - Caenorhabditis elega...   140  2e-32
gi|4758276 erythrocyte membrane protein band 7.2 (stomatin) [Hom...   140  2e-32
gb|AAA58432.1| (M81635) stomatin peptide [Homo sapiens]               140  2e-32
gb|AAC50296.1| (U33931) band 7.2b stomatin [Homo sapiens] >gi|15...   140  2e-32
sp|P54116|BAN7_MOUSE ERYTHROCYTE BAND 7 INTEGRAL MEMBRANE PROTEI...   139  5e-32
pir||JC5221 stomatin - mouse >gi|975689|emb|CAA62503.1| (X91043)...   139  5e-32
sp|Q19958|STO2_CAEEL STO-2 PROTEIN >gi|7500297|pir||T16240 hypot...   139  5e-32
gi|7710018 erythrocyte protein band 7.2; protein 7.2b [Mus muscu...   138  8e-32
gb|AAC64173.1| (AF093620) stomatin [Mus musculus]                     138  8e-32
sp|Q20657|STO3_CAEEL STO-3 PROTEIN >gi|7503947|pir||T22502 hypot...   130  2e-29
gb|AAF54746.1| (AE003694) CG14736 gene product [Drosophila melan...   122  4e-27
gb|AAF52157.1| (AE003607) CG14644 gene product [Drosophila melan...   113  3e-24
gi|7657615 podocin [Homo sapiens] >gi|7363002|emb|CAB83216.1| (A...   106  4e-22
pir||E82334 hflK protein VC0349 [imported] - Vibrio cholerae (gr...   102  6e-21
sp|P40605|HFLK_VIBPA HFLK PROTEIN >gi|507734|gb|AAA62186.1| (U09...   101  1e-20
gb|AAB18857.1| (U50999) stomatin [Mus musculus]                       100  2e-20
pir||B72207 ftsH proteinase activity modulator HflC - Thermotoga...   100  2e-20
pir||A82806 integral membrane proteinase XF0452 [imported] - Xyl...    99  6e-20
sp|P25662|HFLK_ECOLI HFLK PROTEIN >gi|280067|pir||B43653 probabl...    97  2e-19
pir||B83028 proteinase subunit HflK PA4942 [imported] - Pseudomo...    97  2e-19
pir||A72207 ftsH proteinase activity modulator HflK - Thermotoga...    97  3e-19
dbj|BAB06873.1| (AP001517) protease specific for phage lambda cI...    95  8e-19
pir||A71722 hflC protein (hflC) RP123 - Rickettsia prowazekii >g...    94  2e-18
pir||A83028 proteinase subunit HflC PA4941 [imported] - Pseudomo...    92  5e-18
sp|P44546|HFLK_HAEIN HFLK PROTEIN >gi|1075179|pir||A64051 probab...    90  2e-17
gb|AAF47921.1| (AE003481) CG7468 gene product [Drosophila melano...    90  3e-17
sp|O51221|HFLK_BORBU HFLK PROTEIN >gi|7463666|pir||C70125 Lambda...    89  8e-17
sp|P25661|HFLC_ECOLI HFLC PROTEIN >gi|280066|pir||C43653 probabl...    88  1e-16
gi|4759148 stomatin-like protein 1 [Homo sapiens] >gi|4160546|em...    87  3e-16
pir||T32977 unc-24 protein - Caenorhabditis elegans >gi|1353669|...    85  7e-16
sp|P57631|HFLK_BUCAI HFLK PROTEIN >gi|10039224|dbj|BAB13258.1| (...    85  7e-16
emb|CAB52016.1| (AL109665) SLP-1 [Homo sapiens]                        84  2e-15
gb|AAF06960.1| (AF156557) stomatin related protein [Homo sapiens...    84  2e-15
pir||B82806 integral membrane proteinase XF0453 [imported] - Xyl...    84  2e-15
gi|11432457 stomatin-like protein 1 [Homo sapiens]                     84  2e-15
emb|CAB64583.1| (AL135941) hypothetical protein L391.06 [Leishma...    84  2e-15
sp|P57630|HFLC_BUCAI HFLC PROTEIN >gi|10039223|dbj|BAB13257.1| (...    83  3e-15
sp|O83151|HFLK_TREPA HFLK PROTEIN >gi|7521161|pir||H71364 probab...    83  4e-15
gb|AAF03497.1|AC010676_7 (AC010676) unknown protein [Arabidopsis...    80  2e-14
gb|AAF07389.1|AC010675_12 (AC010675) unknown protein; 58197-5941...    80  3e-14
dbj|BAB06874.1| (AP001517) protease specific for phage lambda cI...    80  4e-14
gb|AAF68390.1|AF236374_1 (AF236374) hypersensitive-induced respo...    79  7e-14
gb|AAF68391.1|AF236375_1 (AF236375) hypersensitive-induced respo...    78  2e-13
gb|AAF68389.1|AF236373_1 (AF236373) hypersensitive-induced respo...    77  3e-13
pir||I39620 hypothetical protein X - Anabaena variabilis (fragme...    76  4e-13
pir||E83340 hypothetical protein PA2438 [imported] - Pseudomonas...    76  6e-13
emb|CAC07434.1| (AJ292360) putative membrane protein [Zea mays]        75  8e-13
dbj|BAB08673.1| (AB018109) gb|AAF03497.1~gene_id:K17N15.12~simil...    73  3e-12
pir||C81445 probable transmembrane protein Cj0268c [imported] - ...    73  4e-12
dbj|BAB10843.1| (AB009053) hypersensitive-induced response prote...    73  5e-12
emb|CAB64584.1| (AL135941) hypothetical protein L391.07 [Leishma...    72  7e-12
sp|P44545|HFLC_HAEIN HFLC PROTEIN >gi|1074959|pir||I64050 probab...    71  2e-11
emb|CAA10289.1| (AJ131049) hypothetical protein [Cicer arietinum]      71  2e-11
gb|AAD42031.1|AF074953_1 (AF074953) stomatin-like protein UNC24 ...    69  6e-11

>pir||F75003 stomatin-like protein PAB1324 - Pyrococcus abyssi (strain Orsay)
           >gi|5458982|emb|CAB50468.1| (AJ248288) STOMATIN-LIKE
           PROTEIN [Pyrococcus abyssi]
           Length = 299
           
 Score =  574 bits (1464), Expect = e-163
 Identities = 299/299 (100%), Positives = 299/299 (100%)

Query: 1   MMISAGGVALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERV 60
           MMISAGGVALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERV
Sbjct: 1   MMISAGGVALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERV 60

Query: 61  KVVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNL 120
           KVVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNL
Sbjct: 61  KVVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNL 120

Query: 121 RAIIGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQM 180
           RAIIGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQM
Sbjct: 121 RAIIGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQM 180

Query: 181 TAEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEAL 240
           TAEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEAL
Sbjct: 181 TAEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEAL 240

Query: 241 KMADEKYLTLQYIEKLPDLAKYGNLIVPYDTESLIGLLRVLQKVKSIPLQQSTEKKIEE 299
           KMADEKYLTLQYIEKLPDLAKYGNLIVPYDTESLIGLLRVLQKVKSIPLQQSTEKKIEE
Sbjct: 241 KMADEKYLTLQYIEKLPDLAKYGNLIVPYDTESLIGLLRVLQKVKSIPLQQSTEKKIEE 299


>pir||A71159 probable membrane protein - Pyrococcus horikoshii
           >gi|3256875|dbj|BAA29558.1| (AP000002) 298aa long
           hypothetical membrane protein [Pyrococcus horikoshii]
           Length = 298
           
 Score =  536 bits (1367), Expect = e-152
 Identities = 271/294 (92%), Positives = 287/294 (97%)

Query: 2   MISAGGVALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVK 61
           MI AGG+ALIILG+FLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVK
Sbjct: 5   MIGAGGIALIILGLFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVK 64

Query: 62  VVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLR 121
           +VDLREHVIDVPPQEVICKDNVVVTVDAVVYYQ++DPVKAVYNVSDFLMAIVKLAQTNLR
Sbjct: 65  IVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQVIDPVKAVYNVSDFLMAIVKLAQTNLR 124

Query: 122 AIIGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMT 181
           AIIGEMELDETLSGRDIINA+LREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMT
Sbjct: 125 AIIGEMELDETLSGRDIINARLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMT 184

Query: 182 AEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEALK 241
           AEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEALK
Sbjct: 185 AEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEALK 244

Query: 242 MADEKYLTLQYIEKLPDLAKYGNLIVPYDTESLIGLLRVLQKVKSIPLQQSTEK 295
           +ADEKYL LQYIEKLP+LA+YGNLIVPYDTESL+GLLR++QK++S P  +  E+
Sbjct: 245 LADEKYLALQYIEKLPELARYGNLIVPYDTESLVGLLRMIQKIRSTPAGEKKEE 298


>pir||E72322 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
           >gi|4981401|gb|AAD35948.1|AE001753_4 (AE001753)
           conserved hypothetical protein [Thermotoga maritima]
           Length = 305
           
 Score =  306 bits (776), Expect = 2e-82
 Identities = 158/292 (54%), Positives = 216/292 (73%), Gaps = 15/292 (5%)

Query: 8   VALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVVDLRE 67
           +AL++L  FL+++   S++++RPY++GLVERLGKF R +  G+HFIIPF ER+  VD+RE
Sbjct: 3   IALVVLVFFLIVLAASSIRIVRPYERGLVERLGKFKREVGAGVHFIIPFFERMIKVDMRE 62

Query: 68  HVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEM 127
            VIDVPPQEVI +DNVVVTVDAV+YY+I D  + VYNVS+F MA +KLAQTNLR +IGE+
Sbjct: 63  KVIDVPPQEVITRDNVVVTVDAVIYYEITDAYRVVYNVSNFEMATIKLAQTNLRNVIGEL 122

Query: 128 ELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKR 187
           ELD+TL+ R+ IN KLR  LD+ TD+WGV+ITRVEI++IDPP+DI +AM+KQM AER KR
Sbjct: 123 ELDQTLTSRERINMKLRTVLDEATDKWGVRITRVEIKKIDPPQDITDAMSKQMKAERTKR 182

Query: 188 AMILIAEGKKEAAIREAEGQKQAAILKAEGE-----------KQRQILIAEGQAEAIRKV 236
           A IL AEG K+A I +AEGQK AAIL+AEGE            Q+ IL A GQAEAI+ V
Sbjct: 183 AAILEAEGYKQAEILKAEGQKNAAILRAEGEAEAIKRVAEANMQKLILEARGQAEAIKLV 242

Query: 237 LEALKMAD--EKYLTLQYIEKLPDLA--KYGNLIVPYDTESLIGLLRVLQKV 284
             A+   +  +  LT++Y+E L ++A  +   + +P++  S++  L  + ++
Sbjct: 243 FNAIHEGNPTKDLLTVRYLETLKEMANGQATKIFLPFEASSILASLGAISEI 294


>sp|O26788|Y692_METTH HYPOTHETICAL PROTEIN MTH692 >gi|7447611|pir||C69192 stomatin-like
           protein - Methanobacterium thermoautotrophicum (strain
           Delta H) >gi|2621777|gb|AAB85197.1| (AE000848)
           stomatin-like protein [Methanobacterium
           thermoautotrophicum]
           Length = 318
           
 Score =  292 bits (739), Expect = 4e-78
 Identities = 150/293 (51%), Positives = 209/293 (71%), Gaps = 15/293 (5%)

Query: 11  IILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVVDLREHVI 70
           +I+ + LL++   S+K++RPY+KG+VERLGK+ R ++ G+  IIPF+E +K VD+RE V+
Sbjct: 5   LIIVLVLLVLAFKSLKILRPYEKGVVERLGKYQRTVESGLVVIIPFIEAIKKVDMREQVV 64

Query: 71  DVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELD 130
           DVPPQEVI KDN VV VD V++Y+++DP  AVYNV DF  AI KLAQTNLR IIG++ELD
Sbjct: 65  DVPPQEVITKDNTVVVVDCVIFYEVVDPFNAVYNVVDFYQAITKLAQTNLRNIIGDLELD 124

Query: 131 ETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMI 190
           +TL+ R++IN +LRE LD+ TD+WG ++ RVEIQRI+PP DI EAM+KQM AER KRA I
Sbjct: 125 QTLTSREMINTQLREVLDEATDKWGTRVVRVEIQRIEPPGDIVEAMSKQMKAERMKRAAI 184

Query: 191 LIAEGKKEAAIREAEGQKQAAILKAEGE-----------KQRQILIAEGQAEAIRKVLEA 239
           L AEG K++ I+ AEG KQAAIL+AEG+           K R+I IAEGQA+AI  V  A
Sbjct: 185 LEAEGYKQSEIKRAEGDKQAAILEAEGKAEAIKKVADANKYREIAIAEGQAKAILSVFRA 244

Query: 240 LKMAD--EKYLTLQYIEKLPDLA--KYGNLIVPYDTESLIGLLRVLQKVKSIP 288
           +   D     + L+Y+E L  +A  +   +++P +   ++G +  + ++ S P
Sbjct: 245 MHEGDPTNDIIALKYLEALEKVADGRATKILLPVEATGILGSIAGISEMLSDP 297


>pir||D75311 conserved hypothetical protein - Deinococcus radiodurans  (strain
           R1) >gi|6459936|gb|AAF11687.1|AE002048_7 (AE002048)
           conserved hypothetical protein [Deinococcus radiodurans]
           Length = 344
           
 Score =  244 bits (617), Expect = 8e-64
 Identities = 132/292 (45%), Positives = 193/292 (65%), Gaps = 15/292 (5%)

Query: 8   VALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERV-KVVDLR 66
           + +++L + ++I LL  +K +    +   ER GKF R L PG++ IIP+++R+ + V++ 
Sbjct: 5   IFVVVLVLLVIITLLAGIKSVPQGNEWTQERFGKFQRTLKPGLNLIIPYIDRIGRKVNMM 64

Query: 67  EHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGE 126
           E V DVP QE+I KDN +VTVDAVV+YQ+LD  KA Y V +   A++ L  TN+R + G 
Sbjct: 65  EQVFDVPSQEIITKDNALVTVDAVVFYQVLDAAKASYEVRNLEQAVLNLTMTNIRTVTGS 124

Query: 127 MELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREK 186
           M+LDE LS RD INAKL   +D+ T+ WGVK+TR+E++ I PP D+  +MA+QM AEREK
Sbjct: 125 MDLDELLSNRDTINAKLLVVVDEATEPWGVKVTRIEVKDIKPPADLVASMARQMKAEREK 184

Query: 187 RAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQIL-------IAEGQAEAIRKVLEA 239
           RA IL AEG ++AAI +A+G+KQAA+LKAEGEKQ   +        A+ +AEA R V +A
Sbjct: 185 RANILDAEGFRQAAILKADGEKQAAVLKAEGEKQASFMESEARERRAQAEAEATRVVSQA 244

Query: 240 LK----MADEKYLTLQYIEKLPDLAKYGN---LIVPYDTESLIGLLRVLQKV 284
           +      A   ++  QY+E L D+A   N   LI+P +  S++G L+ + +V
Sbjct: 245 IAGGNVQAVNYFIAQQYVEALRDVASAPNQKTLILPIEATSILGSLQGIAEV 296


>emb|CAB94650.1| (AL359215) putative secreted protein. [Streptomyces coelicolor
           A3(2)]
           Length = 343
           
 Score =  238 bits (602), Expect = 4e-62
 Identities = 127/302 (42%), Positives = 203/302 (67%), Gaps = 9/302 (2%)

Query: 1   MMISAGGVALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERV 60
           M  SA  +A +I+ +  +  ++ +V+++   +   VERLG+++R L PG+  +IP+++RV
Sbjct: 3   MEASAFLIAGVIVALLAVFTVVRAVRIVPQARARNVERLGRYHRTLKPGLSVVIPYIDRV 62

Query: 61  -KVVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTN 119
             V+DLRE V+   PQ VI +DN+VV +D V+Y+Q+ DP  A Y +++FL A+ +L  T 
Sbjct: 63  YPVIDLREQVVSFKPQPVITEDNLVVEIDTVLYFQVTDPRAAFYEIANFLQAVEQLTVTT 122

Query: 120 LRAIIGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQ 179
           LR ++G M+L++TL+ RD IN++LR  LD+ T +WG+++ RVEI+ IDPP+ I++AM KQ
Sbjct: 123 LRNVVGSMDLEKTLTSRDTINSQLRGVLDEATGKWGLRVNRVEIKAIDPPQSIKDAMQKQ 182

Query: 180 MTAEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEA 239
           M AER+KRA IL AEG++++ I  AEG KQAA+L+AEG +  +IL AEGQ+ AI +V +A
Sbjct: 183 MRAERDKRAAILGAEGQRQSQILTAEGDKQAAVLRAEGNRTAEILKAEGQSRAIDEVFQA 242

Query: 240 LKM--ADEKYLTLQYIEKLPDLAKYGN---LIVPYD-TESLIGLLRVLQKVKSIPLQQST 293
           +     D K L  QY++ LP LA+       ++P + T +L G+ R     +++P   +T
Sbjct: 243 VHRNDPDPKLLAYQYLQVLPQLAQGSGSTFWVIPSEVTSALQGVSRAF--TEALPQSPAT 300

Query: 294 EK 295
            +
Sbjct: 301 RE 302


>sp|P71768|YE88_MYCTU HYPOTHETICAL 41.2 KDA PROTEIN RV1488 >gi|7476783|pir||C70711
           hypothetical protein Rv1488 - Mycobacterium tuberculosis
            (strain H37RV) >gi|1524234|emb|CAB02038.1| (Z79701)
           hypothetical protein Rv1488 [Mycobacterium tuberculosis]
           Length = 381
           
 Score =  236 bits (597), Expect = 2e-61
 Identities = 135/309 (43%), Positives = 196/309 (62%), Gaps = 31/309 (10%)

Query: 5   AGGVALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKV-V 63
           AG V L +L IF +I++  SV +I   +  ++ERLG+++R +   +  ++PF++RV+  V
Sbjct: 6   AGLVFLAVLVIFAIIVVAKSVALIPQAEAAVIERLGRYSRTVSGQLTLLVPFIDRVRARV 65

Query: 64  DLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAI 123
           DLRE V+  PPQ VI +DN+ + +D VVY+Q+  P  AVY +S++++ + +L  T LR +
Sbjct: 66  DLRERVVSFPPQPVITEDNLTLNIDTVVYFQVTVPQAAVYEISNYIVGVEQLTTTTLRNV 125

Query: 124 IGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAE 183
           +G M L++TL+ RD INA+LR  LD+ T RWG+++ RVE++ IDPP  IQ +M KQM A+
Sbjct: 126 VGGMTLEQTLTSRDQINAQLRGVLDEATGRWGLRVARVELRSIDPPPSIQASMEKQMKAD 185

Query: 184 REKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAE---------------- 227
           REKRAMIL AEG +EAAI++AEGQKQA IL AEG KQ  IL AE                
Sbjct: 186 REKRAMILTAEGTREAAIKQAEGQKQAQILAAEGAKQAAILAAEADRQSRMLRAQGERAA 245

Query: 228 ------GQAEAIRKVLEALKMA--DEKYLTLQYIEKLPDLAKYGNL----IVPYD-TESL 274
                 GQA+AI K   A+K      + L  QY++ LP++A+ G+     +VP D   +L
Sbjct: 246 AYLQAQGQAKAIEKTFAAIKAGRPTPEMLAYQYLQTLPEMAR-GDANKVWVVPSDFNAAL 304

Query: 275 IGLLRVLQK 283
            G  R+L K
Sbjct: 305 QGFTRLLGK 313


>pir||T36857 conserved hypothetical protein SCI5.04c - Streptomyces coelicolor
           >gi|5123532|emb|CAB45288.1| (AL079332) conserved
           hypothetical protein [Streptomyces coelicolor A3(2)]
           Length = 319
           
 Score =  235 bits (594), Expect = 4e-61
 Identities = 116/257 (45%), Positives = 179/257 (69%), Gaps = 3/257 (1%)

Query: 8   VALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKV-VDLR 66
           + LIIL + + I L+ +++VI      +VER G++ R L+ G++ ++PF++ ++  +DLR
Sbjct: 6   IVLIILVVLVFIALIKTIQVIPQASAAIVERFGRYTRTLNAGLNIVVPFIDTIRNRIDLR 65

Query: 67  EHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGE 126
           E V+  PPQ VI +DN+VV +D V+YYQ+ D   A Y V+ ++ AI +L  T LR IIG 
Sbjct: 66  EQVVPFPPQPVITQDNLVVNIDTVIYYQVTDARAATYEVASYIQAIEQLTVTTLRNIIGG 125

Query: 127 MELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREK 186
           M+L+ TL+ R+ INA LR  LD+ T +WG+++ RVE++ I+PP  IQ++M KQM A+R+K
Sbjct: 126 MDLERTLTSREEINAALRGVLDEATGKWGIRVNRVELKAIEPPTSIQDSMEKQMRADRDK 185

Query: 187 RAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEALKMA--D 244
           RA IL AEG +++ I  AEG+KQ+ IL+AEGE +   L AEG+A+A+R V EA+     D
Sbjct: 186 RAAILQAEGVRQSEILRAEGEKQSQILRAEGEAKAAALRAEGEAQAVRTVFEAIHAGDPD 245

Query: 245 EKYLTLQYIEKLPDLAK 261
           +K L+ QY++ LP +A+
Sbjct: 246 QKLLSYQYLQMLPKIAE 262


>gb|AAF09169.1|AF065260_1 (AF065260) HflC homolog [Clostridium difficile]
           Length = 320
           
 Score =  227 bits (573), Expect = 1e-58
 Identities = 132/315 (41%), Positives = 192/315 (60%), Gaps = 46/315 (14%)

Query: 11  IILGIFLLIML----LLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVK-VVDL 65
           I+L I L++++    L  ++VI+  + G++ RLGKF ++ + G+HF+IPF++++  V+DL
Sbjct: 5   IVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVAETGVHFLIPFLDKMAYVIDL 64

Query: 66  REHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIG 125
           RE VID PPQ VI KDNV + +D VVYY++ DPV+ V+ +++ + AI  L  T LR IIG
Sbjct: 65  REIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVFEIANPIAAIENLTATTLRNIIG 124

Query: 126 EMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAERE 185
           E++LDETL+ +     K     D+ TD+WG+K+ RVE++ I PP+DIQ AM KQM AERE
Sbjct: 125 ELDLDETLTSQRYNKCKNENYPDEATDKWGIKVNRVELKNIMPPQDIQVAMEKQMRAERE 184

Query: 186 KRAMILIAEGKKEAAIREAEGQKQAAILK-----------AEGEKQRQILIAEGQAEAIR 234
           +R  IL AEG K AAI +AEG+KQ+AIL            AEGEK+  IL+AEG+AEAIR
Sbjct: 185 RREAILQAEGNKSAAILQAEGEKQSAILTAEAKKEAMVRVAEGEKESAILVAEGEAEAIR 244

Query: 235 K--------------------------VLEALKMA--DEKYLTLQYIEKLPDLA--KYGN 264
           +                          V  A+K A  D   L L+ +E L  +A  K   
Sbjct: 245 QTAIAKAQGEAEMIKRTQMATAEGLKLVFSAMKEADIDNNILALKSMEALEKMAEGKSTK 304

Query: 265 LIVPYDTESLIGLLR 279
           L++P +  + +G  +
Sbjct: 305 LVLPSEAVNFLGTFK 319


>gi|10955528 77 pct identical to sp:YBBK_ECOLI[hypothetical 33kd protein of E.
           coli] [Escherichia coli] >gi|9971722|dbj|BAB12673.1|
           (AP002527) 77 pct identical to
           sp:YBBK_ECOLI[hypothetical 33kd protein of E. coli]
           [Escherichia coli]
           Length = 325
           
 Score =  219 bits (553), Expect = 2e-56
 Identities = 122/296 (41%), Positives = 184/296 (61%), Gaps = 19/296 (6%)

Query: 8   VALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERV-KVVDLR 66
           + L++L +  LI +  +VK++       VER GK+   L PG+HF+IPFM+R+ + +++ 
Sbjct: 13  IPLLLLILVALIFVKSAVKIVPQGNAWTVERFGKYTHTLSPGLHFLIPFMDRIGQRINMM 72

Query: 67  EHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGE 126
           E V+DVP QEVI KDN  VT+DAV + Q++D  KA Y V +   AI  L  TN+R ++G 
Sbjct: 73  ETVLDVPKQEVISKDNANVTIDAVCFIQVIDAAKAAYEVDNLASAISNLVMTNIRTVVGG 132

Query: 127 MELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREK 186
           M LD+ LS RD IN+KL   +D  TD WG+K+TR+EI+ + PP+++ +AM  QM AER K
Sbjct: 133 MNLDDMLSQRDSINSKLLTVVDYATDPWGIKVTRIEIRDVKPPEELTKAMNAQMKAERTK 192

Query: 187 RAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQIL-------IAEGQAEAIRKVLEA 239
           RA IL AEG +++ I +AEG+KQ+ ILKAEGE+Q   L        AE +A A + V +A
Sbjct: 193 RAQILEAEGIRQSQILKAEGEKQSQILKAEGERQSAFLQSEARERQAEAEARATKLVSDA 252

Query: 240 LKMADEK----YLTLQYIEKLPDLAKYGN---LIVPYDTESLI----GLLRVLQKV 284
           +   D +    ++  +Y E L  +    N   +++P D+ SL+    G+  +L+ V
Sbjct: 253 IAEGDVQSVNYFIAQKYTEALQAIGTASNSKLVMMPLDSSSLVSSVAGISELLKNV 308


>gb|AAG18899.1| (AE004992) bifunctional short chain isoprenyl diphosphate synthase;
           Ids [Halobacterium sp. NRC-1]
           Length = 392
           
 Score =  217 bits (547), Expect = 1e-55
 Identities = 113/279 (40%), Positives = 182/279 (64%), Gaps = 10/279 (3%)

Query: 6   GGVALIILGIFLLIMLLL----SVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVK 61
           GG    ++G+ LL++L +    +V+++  Y+K  +   G++  LL+PGI+ I PF+ R  
Sbjct: 24  GGSLTTVVGLLLLVLLAVVVYETVQIVDAYEKQALTVFGEYRGLLEPGINVIPPFVSRTY 83

Query: 62  VVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLR 121
             D+R   IDVP QE I +DN  VT DAVVY ++ D  +A   V D+  A+  LAQT LR
Sbjct: 84  TFDMRTQTIDVPRQEAITRDNSPVTADAVVYIRVRDAKRAFLEVDDYKTAVSNLAQTTLR 143

Query: 122 AIIGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMT 181
           A++G+MELD+TL+ R  IN+++R ELD+ TD WG+++  VE++ ++P +++Q+AM +Q +
Sbjct: 144 AVLGDMELDDTLNKRQEINSRIRTELDEPTDEWGIRVESVEVREVNPSQEVQQAMEQQTS 203

Query: 182 AEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEA-- 239
           AER +RAMIL A+G++++AI  A+G KQ+ I++A+GEKQ QIL  E Q +AI  VL A  
Sbjct: 204 AERRRRAMILEAQGERQSAIENAQGDKQSNIIRAQGEKQSQIL--EAQGDAISTVLRAKS 261

Query: 240 LKMADEKYLTLQYIEKLPDL--AKYGNLIVPYDTESLIG 276
            +   E+ +  + +E L  +   +    ++P +  SL+G
Sbjct: 262 AESMGERAIIEKGMETLEGIGEGESNTFVLPQEVTSLVG 300


>sp|P77367|YBBK_ECOLI HYPOTHETICAL 33.7 KD PROTEIN IN USHA-TESA INTERGENIC REGION
           >gi|7447609|pir||H64779 probable membrane protein ybbK -
           Escherichia coli >gi|1773171|gb|AAB40243.1| (U82664)
           similar to M. tuberculosis MTCY277.09 [Escherichia coli]
           >gi|1786697|gb|AAC73591.1| (AE000155) putative protease
           [Escherichia coli K12]
           Length = 305
           
 Score =  215 bits (541), Expect = 6e-55
 Identities = 115/285 (40%), Positives = 179/285 (62%), Gaps = 18/285 (6%)

Query: 10  LIILGIFLLIMLLL---SVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERV-KVVDL 65
           LI + I + + L++    VK++    +  VER G++ + L PG+  ++PFM+R+ + +++
Sbjct: 2   LIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPGLSLVVPFMDRIGRKINM 61

Query: 66  REHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIG 125
            E V+D+P QEVI KDN  VT+DAV + Q++D  +A Y VS+  +AI+ L  TN+R ++G
Sbjct: 62  MEQVLDIPSQEVISKDNANVTIDAVCFIQVIDAPRAAYEVSNLELAIINLTMTNIRTVLG 121

Query: 126 EMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAERE 185
            MELDE LS RD IN++L   +D+ T+ WG+K+TR+EI+ + PP ++  +M  QM AER 
Sbjct: 122 SMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIRDVRPPAELISSMNAQMKAERT 181

Query: 186 KRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQIL-------IAEGQAEAIRKVLE 238
           KRA IL AEG ++A I +AEG+KQ+ ILKAEGE+Q   L        AE +A A + V E
Sbjct: 182 KRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATKMVSE 241

Query: 239 ALKMAD----EKYLTLQYIEKLPDLAKYGN---LIVPYDTESLIG 276
           A+   D      ++  +Y E L  +    N   +++P +  SL+G
Sbjct: 242 AIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVMMPLEASSLMG 286


>pir||F82256 conserved hypothetical protein VC0976 [imported] - Vibrio cholerae
           (group O1 strain N16961) >gi|9655437|gb|AAF94138.1|
           (AE004179) conserved hypothetical protein [Vibrio
           cholerae]
           Length = 306
           
 Score =  214 bits (539), Expect = 1e-54
 Identities = 120/284 (42%), Positives = 172/284 (60%), Gaps = 15/284 (5%)

Query: 8   VALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERV-KVVDLR 66
           + + +L + ++I +  +VK +       VER G++ + L PG++ IIPF++RV   +++ 
Sbjct: 7   ITIAVLVLAVVIFISSAVKTVPQGNNWTVERFGRYTQTLKPGLNLIIPFIDRVGHKINMM 66

Query: 67  EHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGE 126
           E V+D+P QEVI KDN  V +DAV + Q++D  KA Y VS    AI  L  TN+R ++G 
Sbjct: 67  EQVLDIPAQEVISKDNANVVIDAVCFVQVIDAAKAAYEVSQLQHAIRNLTLTNMRTVLGS 126

Query: 127 MELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREK 186
           MELDE LS RD+IN KL   +D  T  WGVK+TR+EI+ + PP D+  AM  QM AER K
Sbjct: 127 MELDEMLSQRDMINTKLLSIVDHATSPWGVKVTRIEIKDVQPPADLTAAMNAQMKAERNK 186

Query: 187 RAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQIL-------IAEGQAEAIRKVLEA 239
           RA +L AEG ++A I  AEGQKQ+ ILKAEGEKQ  IL        AE +A+A   V EA
Sbjct: 187 RAEVLEAEGVRQAQILRAEGQKQSEILKAEGEKQAAILQAEARERAAEAEAKATTMVSEA 246

Query: 240 LKMADEK----YLTLQYIEKLPDLAKYGN---LIVPYDTESLIG 276
           +   D +    ++   Y E L  + +  N   +++P +   L+G
Sbjct: 247 IAKGDMQAVNYFIAQGYTEALKAIGQAENGKIIMLPLEATGLMG 290


>sp|Q58237|Y827_METJA HYPOTHETICAL PROTEIN MJ0827 >gi|2129105|pir||C64403 membrane
           protein homolog - Methanococcus jannaschii
           >gi|1591514|gb|AAB98826.1| (U67526) membrane protein,
           putative regulator of cation conductance [Methanococcus
           jannaschii]
           Length = 199
           
 Score =  206 bits (518), Expect = 3e-52
 Identities = 103/187 (55%), Positives = 138/187 (73%)

Query: 11  IILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVVDLREHVI 70
           +ILGI  L +++ ++ ++  Y+ GL+ RLG+    L PGI+ IIPF++    VD+R  V 
Sbjct: 11  LILGIIALFIIVKAIVIVNQYEGGLIFRLGRVIGKLKPGINIIIPFLDVPVKVDMRTRVT 70

Query: 71  DVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELD 130
           D+PPQE+I KDN VV VDAVVYY+++D  KA+  V D+  AI+ LAQT LRAIIG MELD
Sbjct: 71  DIPPQEMITKDNAVVKVDAVVYYRVIDVEKAILEVEDYEYAIINLAQTTLRAIIGSMELD 130

Query: 131 ETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMI 190
           E L+ R+ IN+KL E LD+ TD WGV+I +VE++ IDPP+DI+ AMA+QM AER KRA I
Sbjct: 131 EVLNKREYINSKLLEILDRETDAWGVRIEKVEVKEIDPPEDIKNAMAQQMKAERLKRAAI 190

Query: 191 LIAEGKK 197
           L AEG+K
Sbjct: 191 LEAEGEK 197


>pir||A82838 conserved hypothetical protein XF0185 [imported] - Xylella
           fastidiosa (strain 9a5c)
           >gi|9104984|gb|AAF82998.1|AE003872_9 (AE003872)
           conserved hypothetical protein [Xylella fastidiosa]
           Length = 337
           
 Score =  202 bits (509), Expect = 4e-51
 Identities = 111/290 (38%), Positives = 183/290 (62%), Gaps = 16/290 (5%)

Query: 2   MISAGGVALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERV- 60
           M+    +ALI+L +  +I+L  SV ++    +  VE+ G++   + PG+HF+IP +  V 
Sbjct: 20  MLPNNVLALIVL-VAGVILLFKSVIMVPQGYEWTVEKFGRYTDTMKPGLHFLIPLIYSVG 78

Query: 61  KVVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNL 120
           + V + E V+ VP QEVI KDN  V VD VV++Q+LD  KA Y V++  +A++ L QTN+
Sbjct: 79  RKVSMMEQVLAVPSQEVITKDNAGVRVDGVVFFQVLDAAKAAYEVANLEIAMIALVQTNI 138

Query: 121 RAIIGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQM 180
           R ++G ++ DE+LS R+ INAKL   ++  T  WGVK+TR++I+ I PP ++ E+M +Q 
Sbjct: 139 RTVVGSIDFDESLSQRETINAKLLSVVEHATSPWGVKVTRIDIKDIQPPHNLAESMQQQK 198

Query: 181 TAEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQI-------LIAEGQAEAI 233
            AE+ +RA IL AEG +++AI  A+G+KQAA+++AEG K+           +AE +A+A 
Sbjct: 199 MAEQTRRATILEAEGVRQSAILRADGEKQAAVMEAEGRKEAAFRDAEARERLAEAEAKAT 258

Query: 234 RKVLEALKMADEK----YLTLQYIEKLPDLAKYGN---LIVPYDTESLIG 276
           R + EA+   + +    ++  +Y+E   +LA   N   +++P +T  +IG
Sbjct: 259 RILSEAISQGNVQAVNYFVAQKYVEAFKELATAPNQKFILMPMETSGIIG 308


>sp|P72655|YB28_SYNY3 HYPOTHETICAL 35.7 KD PROTEIN SLR1128 >gi|7447608|pir||S74505
           erthyrocyte band 7 integral membrane protein -
           Synechocystis sp. (strain PCC 6803)
           >gi|1651729|dbj|BAA16657.1| (D90899) erthyrocyte band 7
           integral membrane protein, protein 7.2B, stomatin
           [Synechocystis sp.]
           Length = 321
           
 Score =  202 bits (509), Expect = 4e-51
 Identities = 109/222 (49%), Positives = 151/222 (67%), Gaps = 3/222 (1%)

Query: 24  SVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVVDL-REHVIDVPPQEVICKDN 82
           SVK++    + LVERLG +N+ L PG++F +P ++RV      RE VID+PPQ  I KDN
Sbjct: 19  SVKIVNEKNEYLVERLGSYNKKLTPGLNFTVPILDRVVFKQTTREKVIDIPPQSCITKDN 78

Query: 83  VVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAK 142
           V +T DAVVY++I+D  KA Y V +   A+V L  T +R+ IG++ELD+T + R  IN  
Sbjct: 79  VAITADAVVYWRIIDMEKAYYKVENLQSAMVNLVLTQIRSEIGKLELDQTFTARTEINEL 138

Query: 143 LREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIR 202
           L  ELD  TD WGVK+TRVE++ I P K + ++M  QMTAER+KRA IL +EG++++AI 
Sbjct: 139 LLRELDISTDPWGVKVTRVELRDIMPSKAVLDSMELQMTAERKKRAAILTSEGQRDSAIN 198

Query: 203 EAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEALKMAD 244
            A+G  QA +L+AE +K+  IL AE  AE  +KVLEA   A+
Sbjct: 199 SAQGDAQARVLEAEAKKKAAILNAE--AEQQKKVLEAKATAE 238


>gb|AAK42367.1| Erythrocyte band 7 membrane protein homolog [Sulfolobus
           solfataricus]
           Length = 267
           
 Score =  196 bits (494), Expect = 2e-49
 Identities = 97/201 (48%), Positives = 150/201 (74%), Gaps = 1/201 (0%)

Query: 1   MMISAGG-VALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMER 59
           M IS G  V ++ L I ++I + +S +V+R +++ +V RLG+F R+  PGI F+IPF++R
Sbjct: 1   MAISIGDIVGIVFLIIIIIIFIAMSFRVVREWERAVVLRLGRFLRVKGPGIIFLIPFVDR 60

Query: 60  VKVVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTN 119
             VVDLR + ++VPPQ ++ KDNV V+VDAVVYY+++DP KAV +V ++ +A++ LAQT+
Sbjct: 61  PLVVDLRVNTVEVPPQTILTKDNVTVSVDAVVYYKVVDPQKAVLSVFNYNVAVLNLAQTS 120

Query: 120 LRAIIGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQ 179
           LR I+G+MELDE LS R+ IN +++E LD  T+ WG+K+T V I+ I   +D+  AMAKQ
Sbjct: 121 LRDIVGQMELDELLSKREEINKRIQEILDVTTEGWGIKVTAVTIRDIRLSQDLLSAMAKQ 180

Query: 180 MTAEREKRAMILIAEGKKEAA 200
             AER +RA ++++EG+++AA
Sbjct: 181 AEAERLRRAKVILSEGERQAA 201


>gb|AAF42660.1|AF226511_1 (AF226511) membrane protein GNA1220 [Neisseria meningitidis]
           >gi|7228856|gb|AAF42662.1|AF226513_1 (AF226513) membrane
           protein GNA1220 [Neisseria meningitidis]
           >gi|7228860|gb|AAF42664.1|AF226515_1 (AF226515) membrane
           protein GNA1220 [Neisseria meningitidis]
           >gi|7228864|gb|AAF42666.1|AF226517_1 (AF226517) membrane
           protein GNA1220 [Neisseria meningitidis]
           >gi|7228866|gb|AAF42667.1|AF226518_1 (AF226518) membrane
           protein GNA1220 [Neisseria meningitidis]
           >gi|7228871|gb|AAF42669.1|AF226521_1 (AF226521) membrane
           protein GNA1220 [Neisseria meningitidis]
           >gi|7228875|gb|AAF42671.1|AF226523_1 (AF226523) membrane
           protein GNA1220 [Neisseria meningitidis]
           >gi|7228891|gb|AAF42679.1|AF226531_1 (AF226531) membrane
           protein GNA1220 [Neisseria meningitidis]
           >gi|7228901|gb|AAF42684.1|AF226536_1 (AF226536) membrane
           protein GNA1220 [Neisseria meningitidis]
           >gi|7228903|gb|AAF42685.1|AF226537_1 (AF226537) membrane
           protein GNA1220 [Neisseria meningitidis]
           >gi|7228907|gb|AAF42687.1|AF226539_1 (AF226539) membrane
           protein GNA1220 [Neisseria meningitidis]
           Length = 315
           
 Score =  192 bits (484), Expect = 3e-48
 Identities = 121/303 (39%), Positives = 179/303 (58%), Gaps = 29/303 (9%)

Query: 11  IILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVV-DLREHV 69
           IIL + + +    S  VI   +  +VERLG+F+R L  G++ +IPF++RV     L+E  
Sbjct: 5   IILLVAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSLKEIP 64

Query: 70  IDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMEL 129
           +DVP Q  I +DN  +TVD ++Y+Q+ DP  A Y  S+++MAI +LAQT LR++IG MEL
Sbjct: 65  LDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIGRMEL 124

Query: 130 DETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAM 189
           D+T   RD IN+ +   LD+    WGVK+ R EI+ + PP++I  +M  Q+TAEREKRA 
Sbjct: 125 DKTFEERDEINSTVVSALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAEREKRAR 184

Query: 190 ILIAEGKK-----------EAAIREAEGQKQAA-----------ILKAEGEKQRQILIAE 227
           I  +EG+K           EA I+++EG+ QAA           I +A+GE +   L+AE
Sbjct: 185 IAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLRLVAE 244

Query: 228 GQAEAIRKVLEALKM---ADEKYLTL--QYIEKLPDLAKYGN-LIVPYDTESLIGLLRVL 281
             AEAIR++  AL+    AD   L +  QY+    +LAK  N LI+P +   +  L+   
Sbjct: 245 ANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSLISAG 304

Query: 282 QKV 284
            K+
Sbjct: 305 MKI 307


>pir||F81107 stomatin/Mec-2 family protein NMB1220 [imported] - Neisseria
           meningitidis (group B strain MD58)
           >gi|7226459|gb|AAF41602.1| (AE002470) stomatin/Mec-2
           family protein [Neisseria meningitidis MC58]
           >gi|7228873|gb|AAF42670.1|AF226522_1 (AF226522) membrane
           protein GNA1220 [Neisseria meningitidis]
           >gi|7228877|gb|AAF42672.1|AF226524_1 (AF226524) membrane
           protein GNA1220 [Neisseria meningitidis]
           >gi|7228879|gb|AAF42673.1|AF226525_1 (AF226525) membrane
           protein GNA1220 [Neisseria meningitidis]
           >gi|7228881|gb|AAF42674.1|AF226526_1 (AF226526) membrane
           protein GNA1220 [Neisseria meningitidis]
           >gi|7228887|gb|AAF42677.1|AF226529_1 (AF226529) membrane
           protein GNA1220 [Neisseria meningitidis]
           >gi|7228889|gb|AAF42678.1|AF226530_1 (AF226530) membrane
           protein GNA1220 [Neisseria meningitidis]
           >gi|7228893|gb|AAF42680.1|AF226532_1 (AF226532) membrane
           protein GNA1220 [Neisseria meningitidis]
           >gi|7228899|gb|AAF42683.1|AF226535_1 (AF226535) membrane
           protein GNA1220 [Neisseria meningitidis]
           >gi|7228905|gb|AAF42686.1|AF226538_1 (AF226538) membrane
           protein GNA1220 [Neisseria meningitidis]
           >gi|7228909|gb|AAF42688.1|AF226540_1 (AF226540) membrane
           protein GNA1220 [Neisseria meningitidis]
           Length = 315
           
 Score =  192 bits (483), Expect = 4e-48
 Identities = 121/303 (39%), Positives = 179/303 (58%), Gaps = 29/303 (9%)

Query: 11  IILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVV-DLREHV 69
           IIL + + +    S  VI   +  +VERLG+F+R L  G++ +IPF++RV     L+E  
Sbjct: 5   IILLVAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSLKEIP 64

Query: 70  IDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMEL 129
           +DVP Q  I +DN  +TVD ++Y+Q+ DP  A Y  S+++MAI +LAQT LR++IG MEL
Sbjct: 65  LDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIGRMEL 124

Query: 130 DETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAM 189
           D+T   RD IN+ +   LD+    WGVK+ R EI+ + PP++I  +M  Q+TAEREKRA 
Sbjct: 125 DKTFEERDEINSTVVAALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAEREKRAR 184

Query: 190 ILIAEGKK-----------EAAIREAEGQKQAA-----------ILKAEGEKQRQILIAE 227
           I  +EG+K           EA I+++EG+ QAA           I +A+GE +   L+AE
Sbjct: 185 IAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLRLVAE 244

Query: 228 GQAEAIRKVLEALKM---ADEKYLTL--QYIEKLPDLAKYGN-LIVPYDTESLIGLLRVL 281
             AEAIR++  AL+    AD   L +  QY+    +LAK  N LI+P +   +  L+   
Sbjct: 245 ANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSLISAG 304

Query: 282 QKV 284
            K+
Sbjct: 305 MKI 307


>gb|AAF44771.1|AF235154_1 (AF235154) GNA1220 [Neisseria gonorrhoeae]
           >gi|7274434|gb|AAF44772.1|AF235155_1 (AF235155) GNA1220
           [Neisseria gonorrhoeae]
           >gi|7274436|gb|AAF44773.1|AF235156_1 (AF235156) GNA1220
           [Neisseria gonorrhoeae]
           Length = 315
           
 Score =  192 bits (483), Expect = 4e-48
 Identities = 122/303 (40%), Positives = 178/303 (58%), Gaps = 29/303 (9%)

Query: 11  IILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVV-DLREHV 69
           IIL   + +    S  VI   +  +VERLG+F+R L  G++ +IPF++RV     L+E  
Sbjct: 5   IILLAAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSLKEIP 64

Query: 70  IDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMEL 129
           +DVP Q  I +DN  +TVD ++Y+Q+ DP  A Y  S+++MAI +LAQT LR++IG MEL
Sbjct: 65  LDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIGRMEL 124

Query: 130 DETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAM 189
           D+T   RD IN+ +   LD+    WGVK+ R EI+ + PP++I  AM  Q+TAEREKRA 
Sbjct: 125 DKTFEERDEINSTVVSALDEAAGAWGVKVLRYEIKDLVPPQEILRAMQAQITAEREKRAR 184

Query: 190 ILIAEGKK-----------EAAIREAEGQKQAA-----------ILKAEGEKQRQILIAE 227
           I  +EG+K           EA I+++EG+ QAA           I +A+GE +   L+AE
Sbjct: 185 IAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLRLVAE 244

Query: 228 GQAEAIRKVLEALKM---ADEKYLTL--QYIEKLPDLAKYGN-LIVPYDTESLIGLLRVL 281
             AEAIR++  AL+    AD   L +  QY+    +LAK  N LI+P +   +  L+   
Sbjct: 245 ANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSLISAG 304

Query: 282 QKV 284
            K+
Sbjct: 305 MKI 307


>pir||H81907 probable periplasmic protein NMA1382 [imported] - Neisseria
           meningitidis (group A strain Z2491)
           >gi|7228854|gb|AAF42661.1|AF226512_1 (AF226512) membrane
           protein GNA1220 [Neisseria meningitidis]
           >gi|7228911|gb|AAF42689.1|AF226541_1 (AF226541) membrane
           protein GNA1220 [Neisseria meningitidis]
           >gi|7380050|emb|CAB84628.1| (AL162755) putative
           periplasmic protein [Neisseria meningitidis Z2491]
           Length = 315
           
 Score =  192 bits (482), Expect = 5e-48
 Identities = 121/303 (39%), Positives = 179/303 (58%), Gaps = 29/303 (9%)

Query: 11  IILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVV-DLREHV 69
           IIL   +++    S  VI   +  +VERLG+F+R L  G++ +IPF++RV     L+E  
Sbjct: 5   IILLAAVVVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSLKEIP 64

Query: 70  IDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMEL 129
           +DVP Q  I +DN  +TVD ++Y+Q+ DP  A Y  S+++MAI +LAQT LR++IG MEL
Sbjct: 65  LDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIGRMEL 124

Query: 130 DETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAM 189
           D+T   RD IN+ +   LD+    WGVK+ R EI+ + PP++I  +M  Q+TAEREKRA 
Sbjct: 125 DKTFEERDEINSTVVSALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAEREKRAR 184

Query: 190 ILIAEGKK-----------EAAIREAEGQKQAA-----------ILKAEGEKQRQILIAE 227
           I  +EG+K           EA I+++EG+ QAA           I +A+GE +   L+AE
Sbjct: 185 IAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLRLVAE 244

Query: 228 GQAEAIRKVLEALKM---ADEKYLTL--QYIEKLPDLAKYGN-LIVPYDTESLIGLLRVL 281
             AEAIR++  AL+    AD   L +  QY+    +LAK  N LI+P +   +  L+   
Sbjct: 245 ANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSLISAG 304

Query: 282 QKV 284
            K+
Sbjct: 305 MKI 307


>gb|AAF42676.1|AF226528_1 (AF226528) membrane protein GNA1220 [Neisseria meningitidis]
           >gi|7228895|gb|AAF42681.1|AF226533_1 (AF226533) membrane
           protein GNA1220 [Neisseria meningitidis]
           Length = 315
           
 Score =  192 bits (482), Expect = 5e-48
 Identities = 121/303 (39%), Positives = 179/303 (58%), Gaps = 29/303 (9%)

Query: 11  IILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVV-DLREHV 69
           IIL + + +    S  VI   +  +VERLG+F+R L  G++ +IPF++RV     L+E  
Sbjct: 5   IILLVAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSLKEIP 64

Query: 70  IDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMEL 129
           +DVP Q  I +DN  +TVD ++Y+Q+ DP  A Y  S+++MAI +LAQT LR++IG MEL
Sbjct: 65  LDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIGRMEL 124

Query: 130 DETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAM 189
           D+T   RD IN+ +   LD+    WGVK+ R EI+ + PP++I  +M  Q+TAEREKRA 
Sbjct: 125 DKTFEERDEINSIVVSALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAEREKRAR 184

Query: 190 ILIAEGKK-----------EAAIREAEGQKQAA-----------ILKAEGEKQRQILIAE 227
           I  +EG+K           EA I+++EG+ QAA           I +A+GE +   L+AE
Sbjct: 185 IAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLRLVAE 244

Query: 228 GQAEAIRKVLEALKM---ADEKYLTL--QYIEKLPDLAKYGN-LIVPYDTESLIGLLRVL 281
             AEAIR++  AL+    AD   L +  QY+    +LAK  N LI+P +   +  L+   
Sbjct: 245 ANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSLISAG 304

Query: 282 QKV 284
            K+
Sbjct: 305 MKI 307


>sp|O59180|YF11_PYRHO HYPOTHETICAL PROTEIN PH1511 >gi|7447604|pir||C71027 probable
           erythrocyte band7 integral membrane protein - Pyrococcus
           horikoshii >gi|3257936|dbj|BAA30619.1| (AP000006) 266aa
           long hypothetical erythrocyte band7 integral membrane
           protein [Pyrococcus horikoshii]
           Length = 266
           
 Score =  191 bits (481), Expect = 7e-48
 Identities = 94/206 (45%), Positives = 145/206 (69%), Gaps = 2/206 (0%)

Query: 1   MMISAGGVALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERV 60
           MM +       I+ +F+LI L  ++K+++ Y++ ++ RLG+      PG+ FIIP  E+ 
Sbjct: 1   MMFATNFFVTSIILLFILIFLASAIKIVKEYERAVIFRLGRVVGARGPGLFFIIPIFEKA 60

Query: 61  KVVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNL 120
            +VDLR  V+DVP QE I KDNV V V+AVVY++++DPVKAV  V +++MA  +++QT L
Sbjct: 61  VIVDLRTQVLDVPVQETITKDNVPVRVNAVVYFRVVDPVKAVTQVKNYIMATSQISQTTL 120

Query: 121 RAIIGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQM 180
           R++IG+  LDE LS RD +N +L+  +D+ TD WG+K+T VEI+ ++ P  +Q+AMA+Q 
Sbjct: 121 RSVIGQAHLDELLSERDKLNMQLQRIIDEATDPWGIKVTAVEIKDVELPAGMQKAMARQA 180

Query: 181 TAEREKRAMILIAEGKKEAA--IREA 204
            AERE+RA I +AE +++AA  +REA
Sbjct: 181 EAERERRARITLAEAERQAAEKLREA 206


>gb|AAC46209.1| (AF002133) MAV266 [Mycobacterium avium]
           Length = 266
           
 Score =  191 bits (481), Expect = 7e-48
 Identities = 90/206 (43%), Positives = 144/206 (69%), Gaps = 1/206 (0%)

Query: 5   AGGVALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKV-V 63
           AG V L +L IF ++++  SV +I   +  ++ERLG+++R +   +  ++PF++R++  V
Sbjct: 6   AGLVLLAVLVIFAIVVVAKSVALIPLAEAAVIERLGRYSRTVSGSVTLLVPFIDRIRARV 65

Query: 64  DLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAI 123
           DLRE V+  PPQ VI +DN+ + +D VVY+Q+  P  AVY +S++++ + +L  T +R +
Sbjct: 66  DLRERVVSFPPQPVITEDNLTLNIDTVVYFQVTVPQAAVYEISNYIVGVEQLTTTTVRNV 125

Query: 124 IGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAE 183
           +G M L++TL+ RD IN +LR  LD+ T RWG+++ RVE++ IDPP  IQ +M KQM A+
Sbjct: 126 VGGMTLEQTLTSRDQINGQLRGVLDEATGRWGLRVARVELRSIDPPPSIQASMEKQMKAD 185

Query: 184 REKRAMILIAEGKKEAAIREAEGQKQ 209
           REKRAMIL AEG +E+AI+E   + +
Sbjct: 186 REKRAMILTAEGSRESAIKEPRARSR 211


>gb|AAF42668.1|AF226519_1 (AF226519) membrane protein GNA1220 [Neisseria meningitidis]
           Length = 315
           
 Score =  191 bits (481), Expect = 7e-48
 Identities = 121/303 (39%), Positives = 179/303 (58%), Gaps = 29/303 (9%)

Query: 11  IILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVV-DLREHV 69
           IIL   +++    S  VI   +  +VERLG+F+R L  G++ +IPF++RV     L+E  
Sbjct: 5   IILLAAVVVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSLKEIP 64

Query: 70  IDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMEL 129
           +DVP Q  I +DN  +TVD ++Y+Q+ DP  A Y  S+++MAI +LAQT LR++IG MEL
Sbjct: 65  LDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIGRMEL 124

Query: 130 DETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAM 189
           D+T   RD IN+ +   LD+    WGVK+ R EI+ + PP++I  +M  Q+TAEREKRA 
Sbjct: 125 DKTFEERDEINSTVVAALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAEREKRAR 184

Query: 190 ILIAEGKK-----------EAAIREAEGQKQAA-----------ILKAEGEKQRQILIAE 227
           I  +EG+K           EA I+++EG+ QAA           I +A+GE +   L+AE
Sbjct: 185 IAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLRLVAE 244

Query: 228 GQAEAIRKVLEALKM---ADEKYLTL--QYIEKLPDLAKYGN-LIVPYDTESLIGLLRVL 281
             AEAIR++  AL+    AD   L +  QY+    +LAK  N LI+P +   +  L+   
Sbjct: 245 ANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSLISAG 304

Query: 282 QKV 284
            K+
Sbjct: 305 MKI 307


>pir||B75107 stomatin-like protein PAB1933 - Pyrococcus abyssi (strain Orsay)
           >gi|5458082|emb|CAB49571.1| (AJ248285) STOMATIN-LIKE
           PROTEIN [Pyrococcus abyssi]
           Length = 268
           
 Score =  191 bits (480), Expect = 9e-48
 Identities = 96/199 (48%), Positives = 143/199 (71%), Gaps = 3/199 (1%)

Query: 8   VALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVVDLRE 67
           V  IIL +F+LI L  ++K+++ Y++ ++ RLG+      PG+ FIIP  E+  +VDLR 
Sbjct: 9   VTTIIL-LFILIFLASAIKIVKEYERAVIFRLGRVVGARGPGLFFIIPIFEKAVIVDLRT 67

Query: 68  HVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEM 127
            V+DVP QE I KDNV V V+AVVY++++DPVKAV  V +++MA  +++QT LR++IG+ 
Sbjct: 68  QVLDVPVQETITKDNVPVRVNAVVYFRVVDPVKAVTQVKNYIMATSQISQTTLRSVIGQA 127

Query: 128 ELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKR 187
            LDE LS RD +N +L+  +D+ TD WG+K+T VEI+ ++ P  +Q AMAKQ  AERE+R
Sbjct: 128 HLDELLSERDKLNMQLQRIIDEATDPWGIKVTAVEIKDVELPAGMQRAMAKQAEAERERR 187

Query: 188 AMILIAEGKKEAA--IREA 204
           A I +AE +++AA  +REA
Sbjct: 188 ARITLAEAERQAAEKLREA 206


>gb|AAF42663.1|AF226514_1 (AF226514) membrane protein GNA1220 [Neisseria meningitidis]
           >gi|7228862|gb|AAF42665.1|AF226516_1 (AF226516) membrane
           protein GNA1220 [Neisseria meningitidis]
           >gi|7228897|gb|AAF42682.1|AF226534_1 (AF226534) membrane
           protein GNA1220 [Neisseria meningitidis]
           Length = 315
           
 Score =  190 bits (479), Expect = 1e-47
 Identities = 121/303 (39%), Positives = 178/303 (57%), Gaps = 29/303 (9%)

Query: 11  IILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVV-DLREHV 69
           IIL   + +    S  VI   +  +VERLG+F+R L  G++ +IPF++RV     L+E  
Sbjct: 5   IILLAAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSLKEIP 64

Query: 70  IDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMEL 129
           +DVP Q  I +DN  +TVD ++Y+Q+ DP  A Y  S+++MAI +LAQT LR++IG MEL
Sbjct: 65  LDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIGRMEL 124

Query: 130 DETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAM 189
           D+T   RD IN+ +   LD+    WGVK+ R EI+ + PP++I  +M  Q+TAEREKRA 
Sbjct: 125 DKTFEERDEINSTVVAALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAEREKRAR 184

Query: 190 ILIAEGKK-----------EAAIREAEGQKQAA-----------ILKAEGEKQRQILIAE 227
           I  +EG+K           EA I+++EG+ QAA           I +A+GE +   L+AE
Sbjct: 185 IAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLRLVAE 244

Query: 228 GQAEAIRKVLEALKM---ADEKYLTL--QYIEKLPDLAKYGN-LIVPYDTESLIGLLRVL 281
             AEAIR++  AL+    AD   L +  QY+    +LAK  N LI+P +   +  L+   
Sbjct: 245 ANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSLISAG 304

Query: 282 QKV 284
            K+
Sbjct: 305 MKI 307


>gb|AAF42675.1|AF226527_1 (AF226527) membrane protein GNA1220 [Neisseria meningitidis]
           Length = 315
           
 Score =  190 bits (478), Expect = 2e-47
 Identities = 121/303 (39%), Positives = 178/303 (57%), Gaps = 29/303 (9%)

Query: 11  IILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVV-DLREHV 69
           IIL   + +    S  VI   +  +VERLG+F+R L  G++ +IPF++RV     L+E  
Sbjct: 5   IILLAAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGLNILIPFIDRVAYRHSLKEIP 64

Query: 70  IDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMEL 129
           +DVP Q  I +DN  +TVD ++Y+Q+ DP  A Y  S+++MAI +LAQT LR++IG MEL
Sbjct: 65  LDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSNYIMAITQLAQTTLRSVIGRMEL 124

Query: 130 DETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAM 189
           D+T   RD IN+ +   LD+    WGVK+ R EI+ + PP++I  +M  Q+TAEREKRA 
Sbjct: 125 DKTFEERDEINSIVVSALDEAAGAWGVKVLRYEIKDLVPPQEILRSMQAQITAEREKRAR 184

Query: 190 ILIAEGKK-----------EAAIREAEGQKQAA-----------ILKAEGEKQRQILIAE 227
           I  +EG+K           EA I+++EG+ QAA           I +A+GE +   L+AE
Sbjct: 185 IAESEGRKIEQINLASGQREAEIQQSEGEAQAAVNASNAEKIARINRAKGEAESLRLVAE 244

Query: 228 GQAEAIRKVLEALKM---ADEKYLTL--QYIEKLPDLAKYGN-LIVPYDTESLIGLLRVL 281
             AEAIR++  AL+    AD   L +  QY+    +LAK  N LI+P +   +  L+   
Sbjct: 245 ANAEAIRQIAAALQTQGGADAVNLKIAEQYVAAFNNLAKESNTLIMPANVADIGSLISAG 304

Query: 282 QKV 284
            K+
Sbjct: 305 MKI 307


>pir||D72522 probable erythrocyte band 7 integral membrane protein APE2153 -
           Aeropyrum pernix (strain K1) >gi|5105852|dbj|BAA81164.1|
           (AP000063) 278aa long hypothetical erythrocyte band 7
           integral membrane protein [Aeropyrum pernix]
           Length = 278
           
 Score =  190 bits (477), Expect = 2e-47
 Identities = 115/279 (41%), Positives = 169/279 (60%), Gaps = 38/279 (13%)

Query: 7   GVALIILGIFLLIMLLL---SVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVV 63
           G ALI +G+ LLI+L+L   S+K++R Y++ ++ RLG+   +  PG+  IIPF++ +  V
Sbjct: 18  GQALIPVGVALLIVLILLSMSIKIVREYERAVIFRLGRLIGVKGPGLFLIIPFVDTLVKV 77

Query: 64  DLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAI 123
           DLR   +D+P Q  I KDNV V VDAVVYY++ DP KAV  + ++  A+V LAQT LR +
Sbjct: 78  DLRIVTVDIPEQRTITKDNVTVGVDAVVYYKVFDPEKAVVRIENYHYAVVMLAQTTLRDV 137

Query: 124 IGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAE 183
           IG++ELD+ L+ R+ IN KL+E LD++TD WG+K+T V I+ +  P+ +  AMAKQ  AE
Sbjct: 138 IGQVELDDLLTKREEINKKLQEILDQLTDPWGIKVTAVTIKEVKLPESMLRAMAKQAEAE 197

Query: 184 REKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEALKMA 243
           R +RA I+           EAEG++QAA + AE             AE   K   AL+  
Sbjct: 198 RWRRARII-----------EAEGERQAAKIMAEA------------AEFYEKHPAALR-- 232

Query: 244 DEKYLTLQYIEKLPDLAKYGNLIV----PYDTESLIGLL 278
                 L+ ++ L ++AK  NL+V        E +IGL+
Sbjct: 233 ------LRELQTLIEVAKEKNLVVVTPLRMGAEDMIGLM 265


>gi|11499015 membrane protein [Archaeoglobus fulgidus]
           >gi|6647985|sp|O28852|YE20_ARCFU HYPOTHETICAL PROTEIN
           AF1420 >gi|7447605|pir||C69427 membrane protein homolog
           - Archaeoglobus fulgidus >gi|2649154|gb|AAB89829.1|
           (AE001006) membrane protein [Archaeoglobus fulgidus]
           Length = 249
           
 Score =  189 bits (475), Expect = 3e-47
 Identities = 101/237 (42%), Positives = 154/237 (64%), Gaps = 5/237 (2%)

Query: 15  IFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVVDLREHVIDVPP 74
           I +++ LL +V++++ Y++G++ RLG+      PG+ FIIP +E + VVDLR    DVP 
Sbjct: 10  IVVVLFLLSAVRIVKEYERGVIFRLGRLVGARGPGLFFIIPILENMVVVDLRTVTYDVPS 69

Query: 75  QEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLS 134
           QEV+ KDNV V V+AVVYY+++DP KAV  V D+  A  +LAQT LR+IIG+ ELDE LS
Sbjct: 70  QEVVTKDNVTVKVNAVVYYRVVDPAKAVTEVFDYQYATAQLAQTTLRSIIGQAELDEVLS 129

Query: 135 GRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAE 194
            RD +N KL++ +D+ T+ WG+K+T VEI+ ++ P++++  MA Q  AERE+R+ I+ AE
Sbjct: 130 ERDKLNVKLQQIIDEETNPWGIKVTAVEIKDVELPEEMRRIMAMQAEAERERRSKIIRAE 189

Query: 195 GKKEAAIREAE-----GQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEALKMADEK 246
           G+ +AA++  E      Q + AIL    +   +I   +     +   +E LK   EK
Sbjct: 190 GEYQAAMKLREAADVLAQSEGAILLRYLQTLNEISAEQNTTIVMPIPVELLKFFVEK 246


>pir||F70378 erythrocyte band 7 homolog - Aquifex aeolicus
           >gi|2983432|gb|AAC07014.1| (AE000713) erythrocyte band 7
           homolog [Aquifex aeolicus]
           Length = 253
           
 Score =  183 bits (461), Expect = 2e-45
 Identities = 91/198 (45%), Positives = 138/198 (68%)

Query: 11  IILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVVDLREHVI 70
           I + I +L+ L  ++KVI  Y++ +V RLG+      PG+  +IP ++R+  V LR   +
Sbjct: 9   IFIAILVLLFLASAIKVIPEYERAVVFRLGRVIGAKGPGLIIVIPIIDRIVRVSLRTVTL 68

Query: 71  DVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELD 130
           DVP Q+VI KDNV V VDAVVY++++DPVKA+  V D+  A  ++AQT LR++ GE ELD
Sbjct: 69  DVPTQDVITKDNVTVQVDAVVYFRVVDPVKAIVEVEDYFYATSQIAQTTLRSVCGEAELD 128

Query: 131 ETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMI 190
           E LS R+ IN KL+E +D+ TD WGVK+  VE+++ID P+++++A+A+Q  AERE+RA I
Sbjct: 129 ELLSQREKINMKLQEIIDRQTDPWGVKVIAVELKKIDLPEELRKALARQAEAERERRAKI 188

Query: 191 LIAEGKKEAAIREAEGQK 208
           + AE + +AA +  E  +
Sbjct: 189 ISAEAEYQAAQKLLEAAR 206


>pir||T39599 conserved hypothetical protein SPBC16G5.07c - fission yeast
           (Schizosaccharomyces pombe) >gi|3133101|emb|CAA19027.1|
           (AL023554) conserved hypothetical protein.
           [Schizosaccharomyces pombe]
           Length = 354
           
 Score =  183 bits (459), Expect = 3e-45
 Identities = 110/292 (37%), Positives = 169/292 (57%), Gaps = 30/292 (10%)

Query: 35  LVERLGKFNRLLDPGIHFIIPFMERVKVV-DLREHVIDVPPQEVICKDNVVVTVDAVVYY 93
           +VER+G+F+R+L PG+ F+ P ++++  +  L+E  +++P Q  I  DNV + +D V+Y 
Sbjct: 63  VVERMGRFSRILTPGVAFLAPIIDKIAYIHSLKERALEIPTQSAITLDNVSLGLDGVLYI 122

Query: 94  QILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKLREELDKITDR 153
           Q+ DP KA Y V D   AI +LAQT +R+ IG + LD  L  R  +N  + + ++K  + 
Sbjct: 123 QVYDPYKASYGVEDADYAISQLAQTTMRSEIGRLTLDHVLRERQSLNIHITDAINKAAES 182

Query: 154 WGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQAAIL 213
           WG++  R EI+ I PP+ +  AM +Q++AER+KRA IL +EGK++AAI  AEG KQA IL
Sbjct: 183 WGIRCLRHEIRDIRPPESVVMAMHQQVSAERQKRAEILESEGKRQAAINVAEGDKQAEIL 242

Query: 214 KAEGEKQRQILIAEGQAEAIRKVLEALK-----MAD------------EKYLTLQYIEKL 256
            +EG+K + I  A  +A+AIR+   A       +AD              Y+  QYI   
Sbjct: 243 DSEGQKIKTINSALAEAQAIREKASATASGIAVLADSIKKQEHGLEAVSLYIAQQYITNF 302

Query: 257 PDLAKYGN-LIVPYDTESLIGL----LRVLQKV-------KSIPLQQSTEKK 296
             LAK  N +IVP  T  + G+    L + ++V       KS P +  T++K
Sbjct: 303 GKLAKASNSMIVPASTSDVSGMVAQALSIFKQVSKTTAPDKSTPKELHTDEK 354


>pir||B71689 hypothetical protein RP328 - Rickettsia prowazekii
           >gi|3860888|emb|CAA14788.1| (AJ235271) unknown
           [Rickettsia prowazekii]
           Length = 311
           
 Score =  182 bits (458), Expect = 3e-45
 Identities = 110/310 (35%), Positives = 176/310 (56%), Gaps = 27/310 (8%)

Query: 9   ALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVVD-LRE 67
           AL+I  I  +++++  VKV+   Q  +VE+LGKF+++L PG++ +IP ++RV     L+E
Sbjct: 4   ALLIFSIITILVIIQMVKVVPQQQAWVVEKLGKFDKVLQPGLNLLIPIIQRVAYKHTLKE 63

Query: 68  HVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEM 127
             IDV  Q  I  DNV +++D V+Y +I+DP+ A Y V++   AI +LAQT +R+ IG++
Sbjct: 64  EAIDVTAQTAISNDNVTLSIDGVLYVKIIDPMAASYGVNNPYYAITQLAQTTMRSEIGKL 123

Query: 128 ELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKR 187
            LD T   RD +N  +   +++    WG++  R EI+ I PP+ I +AM  Q+ AER+KR
Sbjct: 124 PLDRTFEERDTLNVAIVSAINQAAINWGIQCMRYEIKDIQPPQTILKAMELQVAAERQKR 183

Query: 188 AMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKV-------LEAL 240
           A IL +EG ++A I  AEG+K   +L +E     Q+  A+G+AEAI  V       +E +
Sbjct: 184 AQILESEGNRQAKINHAEGEKAQIVLNSEASYTDQVNRAKGEAEAIGLVATATANSIEIV 243

Query: 241 KMADEK---------YLTLQYIEKLPDLAKYGNLIV-----PYDTESLIGLLRVLQKVKS 286
             A +K          +  QYI    +LAK  N ++        +  + G L +  ++K+
Sbjct: 244 AAAIQKTGGSDAVALKIAEQYISAFGNLAKDTNTVILPTNLSEPSSFVTGALTIFNQLKT 303

Query: 287 IPLQQSTEKK 296
                S EKK
Sbjct: 304 -----SAEKK 308


>gi|7305503 stomatin-like protein 2 [Homo sapiens]
           >gi|6456118|gb|AAF09142.1|AF190167_1 (AF190167) membrane
           associated protein SLP-2 [Homo sapiens]
           >gi|9652259|gb|AAF91466.1|AF282596_1 (AF282596)
           stomatin-like protein 2 [Homo sapiens]
           Length = 356
           
 Score =  179 bits (449), Expect = 4e-44
 Identities = 105/274 (38%), Positives = 164/274 (59%), Gaps = 22/274 (8%)

Query: 24  SVKVIRPYQKG-LVERLGKFNRLLDPGIHFIIPFMERVKVVD-LREHVIDVPPQEVICKD 81
           +V +  P Q+  +VER+G+F+R+L+PG++ +IP ++R++ V  L+E VI+VP Q  +  D
Sbjct: 36  TVVLFVPQQEAWVVERMGRFHRILEPGLNILIPVLDRIRYVQSLKEIVINVPEQSAVTLD 95

Query: 82  NVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINA 141
           NV + +D V+Y +I+DP KA Y V D   A+ +LAQT +R+ +G++ LD+    R+ +NA
Sbjct: 96  NVTLQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNA 155

Query: 142 KLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAI 201
            + + +++  D WG++  R EI+ I  P  ++E+M  Q+ AER KRA +L +EG +E+AI
Sbjct: 156 SIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAI 215

Query: 202 REAEGQKQAAILKAEGEKQRQILIAEGQ-----------AEAIRKVLEALKM-----ADE 245
             AEG+KQA IL +E EK  QI  A G+           AEAIR +  AL       A  
Sbjct: 216 NVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAAALTQHNGDAAAS 275

Query: 246 KYLTLQYIEKLPDLAKYGNLIV----PYDTESLI 275
             +  QY+     LAK  N I+    P D  S++
Sbjct: 276 LTVAEQYVSAFSKLAKDSNTILLPSNPGDVTSMV 309


>gi|11429564 stomatin-like protein 2 [Homo sapiens]
           Length = 377
           
 Score =  179 bits (449), Expect = 4e-44
 Identities = 105/274 (38%), Positives = 164/274 (59%), Gaps = 22/274 (8%)

Query: 24  SVKVIRPYQKG-LVERLGKFNRLLDPGIHFIIPFMERVKVVD-LREHVIDVPPQEVICKD 81
           +V +  P Q+  +VER+G+F+R+L+PG++ +IP ++R++ V  L+E VI+VP Q  +  D
Sbjct: 57  TVVLFVPQQEAWVVERMGRFHRILEPGLNILIPVLDRIRYVQSLKEIVINVPEQSAVTLD 116

Query: 82  NVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINA 141
           NV + +D V+Y +I+DP KA Y V D   A+ +LAQT +R+ +G++ LD+    R+ +NA
Sbjct: 117 NVTLQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNA 176

Query: 142 KLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAI 201
            + + +++  D WG++  R EI+ I  P  ++E+M  Q+ AER KRA +L +EG +E+AI
Sbjct: 177 SIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAI 236

Query: 202 REAEGQKQAAILKAEGEKQRQILIAEGQ-----------AEAIRKVLEALKM-----ADE 245
             AEG+KQA IL +E EK  QI  A G+           AEAIR +  AL       A  
Sbjct: 237 NVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAAALTQHNGDAAAS 296

Query: 246 KYLTLQYIEKLPDLAKYGNLIV----PYDTESLI 275
             +  QY+     LAK  N I+    P D  S++
Sbjct: 297 LTVAEQYVSAFSKLAKDSNTILLPSNPGDVTSMV 330


>pir||A83590 probable stomatin-like protein PA0452 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9946311|gb|AAG03841.1|AE004482_8 (AE004482) probable
           stomatin-like protein [Pseudomonas aeruginosa]
           Length = 264
           
 Score =  178 bits (446), Expect = 9e-44
 Identities = 85/200 (42%), Positives = 146/200 (72%), Gaps = 2/200 (1%)

Query: 1   MMISAGGVALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERV 60
           MM  + G+A+++  +FL ++L  +++++R Y++G+V +LG+F ++  PG+  +IP ++++
Sbjct: 1   MMGISYGLAMLL--VFLALLLFSALRILREYERGVVFQLGRFWKVKGPGLVLVIPAIQQM 58

Query: 61  KVVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNL 120
             +DLR  V+DVPPQ+VI +DNV V V+AVVY+++LDP KA+  V ++L A  +LAQT L
Sbjct: 59  VRIDLRTIVLDVPPQDVISRDNVSVKVNAVVYFRVLDPQKAIIQVENYLAATSQLAQTTL 118

Query: 121 RAIIGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQM 180
           RA++G+ ELDE L+ R+ +N  +++ LD  TD WG+K+  VEI+ +D  + +  A+A+Q 
Sbjct: 119 RAVLGKHELDEMLAERERLNLDIQQVLDAQTDAWGIKVANVEIKHVDLNESMVRAIARQA 178

Query: 181 TAEREKRAMILIAEGKKEAA 200
            AERE+RA ++ AEG+ +A+
Sbjct: 179 EAERERRAKVIHAEGELQAS 198


>gb|AAF29073.1|AF161458_1 (AF161458) HSPC108 [Homo sapiens]
           Length = 342
           
 Score =  177 bits (444), Expect = 1e-43
 Identities = 104/274 (37%), Positives = 163/274 (58%), Gaps = 22/274 (8%)

Query: 24  SVKVIRPYQKG-LVERLGKFNRLLDPGIHFIIPFMERVKVVD-LREHVIDVPPQEVICKD 81
           +V +  P Q+  +VER+G+F+R+L+PG++ +IP ++R++ V  L+E VI+VP Q  +  D
Sbjct: 22  TVVLFVPQQEAWVVERMGRFHRILEPGLNILIPVLDRIRYVQSLKEIVINVPEQSAVTLD 81

Query: 82  NVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINA 141
           NV + +D V+Y +I+DP KA Y V D   A+ +LAQT +R+ +G++ LD+    R+ +NA
Sbjct: 82  NVTLQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNA 141

Query: 142 KLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAI 201
            + + +++  D WG++  R EI+ I  P  ++E+M  Q+ AER KR  +L +EG +E+AI
Sbjct: 142 SIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRPTVLESEGTRESAI 201

Query: 202 REAEGQKQAAILKAEGEKQRQILIAEGQ-----------AEAIRKVLEALKM-----ADE 245
             AEG+KQA IL +E EK  QI  A G+           AEAIR +  AL       A  
Sbjct: 202 NVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAAALTQHNGDAAAS 261

Query: 246 KYLTLQYIEKLPDLAKYGNLIV----PYDTESLI 275
             +  QY+     LAK  N I+    P D  S++
Sbjct: 262 LTVAEQYVSAFSKLAKDSNTILLPSNPGDVTSMV 295


>gb|AAF47110.1| (AE003462) CG2970 gene product [Drosophila melanogaster]
           Length = 323
           
 Score =  175 bits (440), Expect = 4e-43
 Identities = 99/250 (39%), Positives = 150/250 (59%), Gaps = 17/250 (6%)

Query: 35  LVERLGKFNRLLDPGIHFIIPFMERVKVVD-LREHVIDVPPQEVICKDNVVVTVDAVVYY 93
           +VER+G+F+R+LDPG++ ++P  +++K V  L+E  IDVP Q  I  DNV +++D V+Y 
Sbjct: 10  VVERMGRFHRILDPGLNILVPVADKIKYVQSLKEIAIDVPKQSAITSDNVTLSIDGVLYL 69

Query: 94  QILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKLREELDKITDR 153
           +I+DP KA Y V D   AI +LAQT +R+ +G+M +D+    R+ +N  + + ++K ++ 
Sbjct: 70  RIIDPYKASYGVEDPEFAITQLAQTTMRSELGKMSMDKVFRERESLNVSIVDSINKASEA 129

Query: 154 WGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQAAIL 213
           WG+   R EI+ I  P  + EAM  Q+ AER KRA IL +EG +EA I  AEG++++ IL
Sbjct: 130 WGIACLRYEIRDIRLPTRVHEAMQMQVEAERRKRAAILESEGVREAEINIAEGKRKSRIL 189

Query: 214 KAEGEKQRQILIAEGQAEAIRKVLEA--------------LKMADEKYLTL--QYIEKLP 257
            +E E+Q  I  A G+A AI  V +A              L   +   LTL  QYI    
Sbjct: 190 ASEAERQEHINKASGEAAAIIAVADARARSLLAIAKSLSHLDGQNAASLTLAEQYIGAFK 249

Query: 258 DLAKYGNLIV 267
            LAK  N ++
Sbjct: 250 KLAKTNNTMI 259


>pir||T21562 hypothetical protein F30A10.5 - Caenorhabditis elegans
           >gi|3876548|emb|CAB03018.1| (Z81072) predicted using
           Genefinder~Similarity to Human erythrocyte band 7
           integral membrane protein (SW:BAN7_HUMAN), contains
           similarity to Pfam domain: PF01145 (SPFH domain / Band 7
           family), Score=170.0, E-value=1.3e-47, N=1~cDNA EST
           yk543b6.3 comes >
           Length = 334
           
 Score =  173 bits (434), Expect = 2e-42
 Identities = 97/253 (38%), Positives = 156/253 (61%), Gaps = 20/253 (7%)

Query: 35  LVERLGKFNRLLDPGIHFIIPFMERVKVV-DLREHVIDVPPQEVICKDNVVVTVDAVVYY 93
           +VER+GKF ++L+PG++F++P ++++K V +LRE  I++P Q  I  DNV + +D V+Y 
Sbjct: 55  VVERMGKFYKILEPGLNFLLPIIDKIKFVQNLREIAIEIPEQGAITIDNVQLRLDGVLYL 114

Query: 94  QILDPVKAV---YNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKLREELDKI 150
           ++ DP KA    Y V D   A+ +LAQT +R+ +G++ LD     R+++N  +   ++K 
Sbjct: 115 RVFDPYKACDASYGVDDPEFAVTQLAQTTMRSEVGKINLDTVFKERELLNENIVFAINKA 174

Query: 151 TDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQA 210
           +  WG++  R EI+ +  P  IQEAM  Q+ AER+KRA IL +EG +EAAI  AEG K++
Sbjct: 175 SAPWGIQCMRYEIRDMQMPSKIQEAMQMQVEAERKKRAAILESEGIREAAINRAEGDKKS 234

Query: 211 AILKAEGEKQRQILIAEGQAEAI-------RKVLEALKMADEK---------YLTLQYIE 254
           AIL +E  +  +I +A+G+AEA+        K +E + +A EK          +  QY+ 
Sbjct: 235 AILASEAVQAERINVAKGEAEAVILKAESRAKAIERIALALEKDGGANAAGLTVAEQYVG 294

Query: 255 KLPDLAKYGNLIV 267
              +LAK  N +V
Sbjct: 295 AFGNLAKESNTVV 307


>gb|AAF68388.1|AF236372_1 (AF236372) stomatin-like protein [Zea mays]
           Length = 394
           
 Score =  171 bits (429), Expect = 9e-42
 Identities = 104/268 (38%), Positives = 158/268 (58%), Gaps = 20/268 (7%)

Query: 25  VKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVV-DLREHVIDVPPQEVICKDNV 83
           V ++   +  +VER GK+ + L  G H +IP ++R+  V  L+E  I +P Q  I KDNV
Sbjct: 58  VSIVPEKKAYVVERFGKYLKTLGSGFHLLIPAVDRIAYVHSLKEETIPIPHQNAITKDNV 117

Query: 84  VVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKL 143
            + +D+V+Y +I+DP  A Y V + + A+++LAQT +R+ +G++ LD+T   RD +N K+
Sbjct: 118 TIQIDSVIYVKIMDPYLASYGVENPIYAVLQLAQTTMRSELGKITLDKTFEERDALNEKI 177

Query: 144 REELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIRE 203
              +++    WG+K  R EI+ I+PP  I++AM  Q  AER+KRA IL +EG K+A I E
Sbjct: 178 VSAINEAATDWGLKCIRYEIRDINPPAGIRQAMEMQAEAERKKRAQILESEGMKQAQILE 237

Query: 204 AEGQKQAAILKAEGEKQRQILIAEGQAEAI-----------RKVLEAL------KMADEK 246
           +EG+K A IL++EG        A+G AEAI           R V +A+      K A  K
Sbjct: 238 SEGKKTAQILESEGAMLDLANRAKGAAEAILAKSEATARGMRLVSDAMTTEGSAKAASLK 297

Query: 247 YLTLQYIEKLPDLA-KYGNLIVPYDTES 273
            L  QYIE   +LA K   +++P D+ S
Sbjct: 298 -LAEQYIEAFSNLAQKTNTMLLPGDSAS 324


>pir||T02246 hypothetical protein P1.11659_4 - human >gi|2984585|gb|AAC07983.1|
           (AC004472) P1.11659_4 [Homo sapiens]
           Length = 357
           
 Score =  169 bits (424), Expect = 3e-41
 Identities = 105/288 (36%), Positives = 164/288 (56%), Gaps = 36/288 (12%)

Query: 24  SVKVIRPYQKG-LVERLGKFNRLLDPGIHFIIPFMERVKVVD-LREHVIDVPPQEVICKD 81
           +V +  P Q+  +VER+G+F+R+L+PG++ +IP ++R++ V  L+E VI+VP Q  +  D
Sbjct: 23  TVVLFVPQQEAWVVERMGRFHRILEPGLNILIPVLDRIRYVQSLKEIVINVPEQSAVTLD 82

Query: 82  NVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINA 141
           NV + +D V+Y +I+DP KA Y V D   A+ +LAQT +R+ +G++ LD+    R+ +NA
Sbjct: 83  NVTLQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNA 142

Query: 142 KLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQ--------------MTAEREKR 187
            + + +++  D WG++  R EI+ I  P  ++E+M  Q              + AER KR
Sbjct: 143 SIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVGAKEGWEKGLRAPVEAERRKR 202

Query: 188 AMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQ-----------AEAIRKV 236
           A +L +EG +E+AI  AEG+KQA IL +E EK  QI  A G+           AEAIR +
Sbjct: 203 ATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRIL 262

Query: 237 LEALKM-----ADEKYLTLQYIEKLPDLAKYGNLIV----PYDTESLI 275
             AL       A    +  QY+     LAK  N I+    P D  S++
Sbjct: 263 AAALTQHNGDAAASLTVAEQYVSAFSKLAKDSNTILLPSNPGDVTSMV 310


>pir||T18493 hypothetical protein C0800w - malaria parasite (Plasmodium
           falciparum) >gi|3758847|emb|CAB11132.1| (Z98551) band
           7-related protein [Plasmodium falciparum]
           Length = 374
           
 Score =  168 bits (420), Expect = 1e-40
 Identities = 95/251 (37%), Positives = 149/251 (58%), Gaps = 7/251 (2%)

Query: 35  LVERLGKFNRLLDPGIHFIIPFMERVKVV-DLREHVIDVPPQEVICKDNVVVTVDAVVYY 93
           +VERLGK+N+ L  GIHF+IPF++++  V  L+E  I +P Q  I KDNV + +D V+Y 
Sbjct: 89  IVERLGKYNKTLLAGIHFLIPFIDKIAYVFSLKEETITIPNQTAITKDNVTLNIDGVLYI 148

Query: 94  QILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKLREELDKITDR 153
           +  +P  + Y + D + A+ +LAQ  +R+ +G++ LD T   RD +N KL + +++    
Sbjct: 149 KCDNPYNSSYAIEDAVFAVTQLAQVTMRSELGKLTLDATFLERDNLNEKLVKAINESAKN 208

Query: 154 WGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQAAIL 213
           WG+K  R EI+ I  P +I+ AM KQ  AER KRA IL +EG++E+ I  A G+K+ +IL
Sbjct: 209 WGIKCMRYEIRDIILPVNIKNAMEKQAEAERRKRAEILQSEGERESEINIAIGKKRKSIL 268

Query: 214 KAEGEKQRQILIAEGQAEAIRKVLEALKMADEK-----YLTLQYIEKLPDLAKYGN-LIV 267
            AEG+       A+  AEAI  +   +K  D        +  QYI+   ++ K  N +I+
Sbjct: 269 IAEGQSFAIKAKADATAEAIEIISNKIKKLDSNNAISLLVAEQYIDVFSNICKNNNTVII 328

Query: 268 PYDTESLIGLL 278
           P D  ++  L+
Sbjct: 329 PADLNNISSLI 339


>pir||T05863 hypothetical protein T29A15.70 - Arabidopsis thaliana
           >gi|4469009|emb|CAB38270.1| (AL035602) putative protein
           [Arabidopsis thaliana] >gi|7269612|emb|CAB81408.1|
           (AL161571) putative protein [Arabidopsis thaliana]
           Length = 515
           
 Score =  168 bits (420), Expect = 1e-40
 Identities = 85/210 (40%), Positives = 135/210 (63%), Gaps = 1/210 (0%)

Query: 25  VKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVV-DLREHVIDVPPQEVICKDNV 83
           ++++   +  ++ER GK+   L  GIHF+IPF++R+  V  L+E  I +P Q  I KDNV
Sbjct: 63  IRIVPERKAFVIERFGKYATTLPSGIHFLIPFVDRIAYVHSLKEEAIPIPNQTAITKDNV 122

Query: 84  VVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKL 143
            + +D V+Y +I+DP  A Y V   + A+V+LAQT +R+ +G++ LD+T   RD +N K+
Sbjct: 123 SIHIDGVLYVKIVDPKLASYGVESPIYAVVQLAQTTMRSELGKITLDKTFEERDTLNEKI 182

Query: 144 REELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIRE 203
            E ++     WG++  R EI+ I PP  ++ AM  Q  AER+KRA IL +EG++++ I  
Sbjct: 183 VEAINVAAKDWGLQCLRYEIRDIMPPHGVRAAMEMQAEAERKKRAQILESEGERQSHINI 242

Query: 204 AEGQKQAAILKAEGEKQRQILIAEGQAEAI 233
           A+G+K + IL +E  K  Q+  A+G+AEAI
Sbjct: 243 ADGKKSSVILASEAAKMDQVNRAQGEAEAI 272


>dbj|BAA97132.1| (AB018115) contains similarity to stomatin like
           protein~gene_id:MJP23.8 [Arabidopsis thaliana]
           Length = 401
           
 Score =  167 bits (419), Expect = 1e-40
 Identities = 96/267 (35%), Positives = 161/267 (59%), Gaps = 18/267 (6%)

Query: 25  VKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVV-DLREHVIDVPPQEVICKDNV 83
           ++++   +  ++ER GKF+  L  GIHF++PF++R+  V  L+E  I +  Q  I KDNV
Sbjct: 106 IRIVPERKACVIERFGKFHTTLPAGIHFLVPFVDRIAYVHSLKEEAIPIGNQTAITKDNV 165

Query: 84  VVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKL 143
            + +D V+Y +I+DP  A Y V + + A+++LAQT +R+ +G++ LD+T   RD +N K+
Sbjct: 166 SIHIDGVLYVKIVDPKLASYGVENPIYAVMQLAQTTMRSELGKITLDKTFEERDTLNEKI 225

Query: 144 REELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIRE 203
            E ++     WG++  R EI+ I PP  ++ AM  Q  AER+KRA IL +EG+++A I  
Sbjct: 226 VEAINVAAKDWGLQCLRYEIRDIMPPNGVRVAMEMQAEAERKKRAQILESEGERQAHINR 285

Query: 204 AEGQKQAAILKAEGEKQRQILIAEGQAEAI-----------RKVLEALKMA-DEKYLTL- 250
           A+G+K + IL++E     Q+  A+G+AEAI             V ++LK A  E+  +L 
Sbjct: 286 ADGKKSSVILESEAAMMDQVNRAQGEAEAILARAQATAKGLAMVSQSLKEAGGEEAASLR 345

Query: 251 ---QYIEKLPDLAKYG-NLIVPYDTES 273
              QYI+    +AK G  +++P + ++
Sbjct: 346 VAEQYIQAFGKIAKEGTTMLLPSNVDN 372


>pir||G69104 stomatin-like protein - Methanobacterium thermoautotrophicum
           (strain Delta H) >gi|2622911|gb|AAB86246.1| (AE000933)
           stomatin-like protein [Methanobacterium
           thermoautotrophicum]
           Length = 297
           
 Score =  161 bits (403), Expect = 1e-38
 Identities = 87/247 (35%), Positives = 149/247 (60%), Gaps = 13/247 (5%)

Query: 12  ILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVVDLREHVID 71
           +L   +++++ LS+K+++ Y++G+V RLGK   + +PG+  IIP ++R+  V LR   + 
Sbjct: 51  LLAAVIIVIISLSLKIVKQYERGVVFRLGKVIGVREPGLRIIIPIIDRMVRVSLRIVTMP 110

Query: 72  VPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDE 131
           +P Q++I +DNV + V AV Y+++ DP++AV  + D+  A+ +++QT +R +IG+  LDE
Sbjct: 111 IPSQKIITQDNVSIDVAAVAYFKVADPLRAVVAIEDYYGAVNQISQTTVRNVIGQFVLDE 170

Query: 132 TLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMIL 191
            LS    IN K++E +D+ ++ WG+ +T VEI+ I  P+ +Q AMA+Q  AER+KRA I+
Sbjct: 171 VLSETARINEKIKEIIDEHSEPWGINVTTVEIKDIKLPEGMQRAMARQAEAERDKRAKII 230

Query: 192 IAEGKKEAAIREAEG----QKQAAILKAEG---------EKQRQILIAEGQAEAIRKVLE 238
            AEG+  +A +  E     +K    L+            EK   I+       +IR V E
Sbjct: 231 TAEGEYFSAAKLGEAADVIEKHPVALQLRNLQVLAEIATEKNSTIVFPAQFMSSIRDVKE 290

Query: 239 ALKMADE 245
            ++  DE
Sbjct: 291 FIEREDE 297


>gb|AAC64873.1| (AF034831) stomatin like protein [Rhizobium etli]
           Length = 222
           
 Score =  159 bits (399), Expect = 3e-38
 Identities = 89/228 (39%), Positives = 144/228 (63%), Gaps = 18/228 (7%)

Query: 39  LGKFNRLLDPGIHFIIPFMERVKVVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDP 98
           LG+F  +  PG+  +IP+++++  VDLR  V+DVP Q+VI  DNV V V AV+Y++++DP
Sbjct: 8   LGRFTGVKGPGLILLIPYVQQMIRVDLRTRVLDVPSQDVISHDNVSVRVSAVIYFRVIDP 67

Query: 99  VKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKLREELDKITDRWGVKI 158
            K+   V DF+MA  +LAQT LR+++G+ +LDE L+ RD +N+ ++E LD  TD WG+K+
Sbjct: 68  EKSTIQVEDFMMATSQLAQTTLRSVLGKHDLDEMLAERDRLNSDIQEILDAQTDAWGIKV 127

Query: 159 TRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGE 218
             VEI+ +D  + +  A+A+Q  AERE+RA ++ AEG+++AA         A +L+A   
Sbjct: 128 ATVEIKHVDINESMIRAIARQAEAERERRAKVINAEGEQQAA---------AKLLEA--- 175

Query: 219 KQRQILIAEGQAEAIRKVLEALKMADEKYLTLQYIEKLPDLAKYGNLI 266
              +IL  + +A  +R +     +A EK  T+ +    P   + GNL+
Sbjct: 176 --AEILAKQPEAMQLRYLSTLNVIASEKTSTILF----PFPMELGNLM 217


>emb|CAC12423.1| (AL445067) membrane protein 7, erythrocyte (human) related protein
           [Thermoplasma acidophilum]
           Length = 274
           
 Score =  155 bits (387), Expect = 7e-37
 Identities = 79/202 (39%), Positives = 124/202 (61%)

Query: 8   VALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVVDLRE 67
           + LII+ I  LI+LL  + V++ +++ +V  LG++  +  PGI FI P + R   V  R 
Sbjct: 6   ILLIIIIIIALIILLSGIHVLKEWERAIVLTLGRYGGIRGPGIIFITPIVSRGIYVSTRI 65

Query: 68  HVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEM 127
             +    +    KDNV V VDA++YYQ++DP KAV N+ ++ +     AQT LR +IG+ 
Sbjct: 66  QPVQFKTEATFTKDNVPVNVDAIMYYQVIDPQKAVLNIENYSVGTNYAAQTTLREVIGKS 125

Query: 128 ELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKR 187
             DE LS R+ I    RE +D+ T+ WGVK+  VEI+ +  P  +QEAM++Q +AERE+R
Sbjct: 126 MFDELLSEREKIGETAREIIDQKTEAWGVKVASVEIRDVLVPSQLQEAMSRQASAERERR 185

Query: 188 AMILIAEGKKEAAIREAEGQKQ 209
           + + +A+ + EAA +  E  +Q
Sbjct: 186 SRVTLAQAEVEAAQKMVEASRQ 207


>gb|AAF48927.1| (AE003511) CG7633 gene product [Drosophila melanogaster]
           Length = 339
           
 Score =  153 bits (384), Expect = 2e-36
 Identities = 85/206 (41%), Positives = 127/206 (61%), Gaps = 4/206 (1%)

Query: 3   ISAGGVALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNR--LLDPGIHFIIPFMERV 60
           I A  V+++I+ +   I + +  KV+  Y++ ++ R+G+        PG+ F++P ++  
Sbjct: 6   ILATVVSVLIMVLTFPISVFICFKVVSEYERAVIFRMGRLRSGGARGPGVFFVLPCVDDY 65

Query: 61  KVVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNL 120
             VDLR    DVPPQEV+ KD+V VTVDAVVYY+I DP+KAV  V ++  +   LA T L
Sbjct: 66  YPVDLRTVSFDVPPQEVLSKDSVTVTVDAVVYYRISDPLKAVIQVYNYSHSTSLLAATTL 125

Query: 121 RAIIGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQM 180
           R ++G   L E L+ R+ I+  ++  LD+ TD WGVK+ RVEI+ +  P  +Q AMA + 
Sbjct: 126 RNVLGTRNLSELLTERETISHTMQMSLDEATDPWGVKVERVEIKDVSLPTALQRAMAAEA 185

Query: 181 TAEREKRAMILIAEG--KKEAAIREA 204
            A RE RA ++ AEG  K   A+REA
Sbjct: 186 EAAREARAKVIAAEGEMKSSRALREA 211


>gb|AAF48928.1| (AE003511) CG7635 gene product [Drosophila melanogaster]
           Length = 350
           
 Score =  150 bits (375), Expect = 2e-35
 Identities = 97/269 (36%), Positives = 151/269 (56%), Gaps = 22/269 (8%)

Query: 8   VALIILGIFLL---IMLLLSVKVIRPYQKGLVERLGKFNR-LLDPGIHFIIPFMERVKVV 63
           V L  + IF++   I + +  KV+  Y++ ++ RLG+ +     PG+ FI+P ++  + V
Sbjct: 69  VTLFSVLIFIITSPIAIFICFKVVAEYERAIIFRLGRLSGGARGPGMFFILPCIDEYRKV 128

Query: 64  DLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAI 123
           DLR    +VP QE++ KD+V VTVDAVVYY+I DP+ AV  V D+ M+   LA T LR I
Sbjct: 129 DLRTVTFNVPQQEMLTKDSVTVTVDAVVYYRISDPLYAVIQVEDYSMSTRLLAATTLRNI 188

Query: 124 IGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAE 183
           +G   L E L+ R+ +   ++  LD+ T+ WGV + RVEI+ +  P  +Q AMA +  A 
Sbjct: 189 VGTRNLSELLTERETLAHNMQATLDEATEPWGVMVERVEIKDVSLPVSMQRAMAAEAEAA 248

Query: 184 REKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEALKMA 243
           R+ RA ++ AEG+K          K A  LK   +    ++ A   A  +R +     ++
Sbjct: 249 RDARAKVIAAEGEK----------KSATALKEASD----VISASPSALQLRYLQTLSSIS 294

Query: 244 DEKYLTLQY---IEKL-PDLAKYGNLIVP 268
            EK  T+ +   +E L P LAKY +L+ P
Sbjct: 295 AEKNSTIIFPLPMELLTPYLAKYAHLMGP 323


>sp|Q27433|MEC2_CAEEL MECHANOSENSORY PROTEIN 2 >gi|2133486|pir||S60260 stomatin-like
           protein - Caenorhabditis elegans
           >gi|973210|gb|AAA87551.1| (U26735) MEC-2 [Caenorhabditis
           elegans] >gi|973212|gb|AAA87552.1| (U26736) MEC-2
           [Caenorhabditis elegans] >gi|1086680|gb|AAA82333.1|
           (U41021) C. elegans mec-2 (GB:U26735) [Caenorhabditis
           elegans] >gi|1585780|prf||2201490A stomatin-like protein
           [Caenorhabditis elegans]
           Length = 481
           
 Score =  148 bits (370), Expect = 7e-35
 Identities = 86/224 (38%), Positives = 133/224 (58%), Gaps = 11/224 (4%)

Query: 7   GVALIILGIFLLIMLL-----LSVKVIRPYQKGLVERLGKF--NRLLDPGIHFIIPFMER 59
           G  L IL   L+   L     + +KV++ Y++ ++ RLG+        PGI FI+P ++ 
Sbjct: 118 GWILTILSYLLIFFTLPISACMCIKVVQEYERAVIFRLGRLMPGGAKGPGIFFIVPCIDT 177

Query: 60  VKVVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTN 119
            + VDLR    +VPPQE++ KD+V V VDAVVY++I +   +V NV D   +   LAQT 
Sbjct: 178 YRKVDLRVLSFEVPPQEILSKDSVTVAVDAVVYFRISNATISVTNVEDAARSTKLLAQTT 237

Query: 120 LRAIIGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQ 179
           LR I+G   L E LS R+ I+ +++  LD+ T+ WGVK+ RVE++ +  P  +Q AMA +
Sbjct: 238 LRNILGTKTLAEMLSDREAISHQMQTTLDEATEPWGVKVERVEVKDVRLPVQLQRAMAAE 297

Query: 180 MTAEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQI 223
             A RE RA +++AEG+++A    +   K+AA + AE     Q+
Sbjct: 298 AEAAREARAKVIVAEGEQKA----SRALKEAAEVIAESPSALQL 337


>emb|CAA73876.1| (Y13473) stomatin [Danio rerio]
           Length = 284
           
 Score =  147 bits (367), Expect = 2e-34
 Identities = 83/224 (37%), Positives = 130/224 (57%), Gaps = 11/224 (4%)

Query: 7   GVALIILGIFLLIMLL-----LSVKVIRPYQKGLVERLGKFNR--LLDPGIHFIIPFMER 59
           G  L+I  I L ++ L     + +K+++ Y++ ++ RLG+  R     PG+ FI+P  + 
Sbjct: 33  GWILVIFSILLTLLTLPLSIWMCIKIVKEYERAIIFRLGRILRGGAKGPGLFFILPCTDS 92

Query: 60  VKVVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTN 119
              VD+R    D+PPQEV+ KD+V V+VD VVYY++ +   AV N+++   A   LAQT 
Sbjct: 93  FINVDMRTITFDIPPQEVLTKDSVTVSVDGVVYYRVQNATLAVANITNADAATRLLAQTT 152

Query: 120 LRAIIGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQ 179
           LR ++G   L E LS R+ I   ++  LD  TD WG+K+ RVEI+ +  P  +Q AMA +
Sbjct: 153 LRNVLGTKNLAEILSDREEIAHSMQSTLDDATDDWGIKVERVEIKDVKLPLQLQRAMAAE 212

Query: 180 MTAEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQI 223
             A RE RA ++ AEG+  A    +   K+A+++ AE     Q+
Sbjct: 213 AEASREARAKVIAAEGEMNA----SRALKEASLVIAESPSALQL 252


>emb|CAB76415.1| (Z66565) contains similarity to Pfam domain: PF01145 (SPFH domain /
           Band 7 family), Score=369.9, E-value=8.6e-108, N=1~cDNA
           EST yk67b6.5 comes from this gene~cDNA EST yk82a9.5
           comes from this gene~cDNA EST yk392b12.3 comes from this
           gene~cDNA EST yk440> >gi|7321105|emb|CAB82215.1|
           (AL032659) contains similarity to Pfam domain: PF01145
           (SPFH domain / Band 7 family), Score=369.9,
           E-value=8.6e-108, N=1~cDNA EST yk67b6.5 comes from this
           gene~cDNA EST yk82a9.5 comes from this gene~cDNA EST
           yk392b12.3 comes from this gene~cDNA EST yk4>
           Length = 281
           
 Score =  146 bits (364), Expect = 4e-34
 Identities = 84/201 (41%), Positives = 122/201 (59%), Gaps = 6/201 (2%)

Query: 6   GGVALIILGIFLLIMLLLS----VKVIRPYQKGLVERLGKFNR--LLDPGIHFIIPFMER 59
           G +  II  + +L  L LS    +KV++ Y++ ++ RLG+        PGI FIIP +E 
Sbjct: 27  GWIITIISYLVVLFTLPLSAFFCLKVVQEYERAVIFRLGRLKHGGARGPGIFFIIPCIES 86

Query: 60  VKVVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTN 119
            K +DLR    DVPPQE++ KD+V V+VDAV+Y++I +   +V NV D   +   LAQT 
Sbjct: 87  FKKIDLRVVSFDVPPQEILSKDSVTVSVDAVIYFRISNATVSVINVEDAARSTKLLAQTT 146

Query: 120 LRAIIGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQ 179
           LR  +G   L E LS RD I+ +++  LD+ TD WGVK+ RVEI+ +  P  +Q AMA +
Sbjct: 147 LRNFLGTRTLAEMLSSRDAISMQMQAALDEATDPWGVKVERVEIKDVRLPIQLQRAMAAE 206

Query: 180 MTAEREKRAMILIAEGKKEAA 200
             A R   A I+ AEG++ A+
Sbjct: 207 AEAARAAGAKIIAAEGEQLAS 227


>pir||T34691 hypothetical protein SC1B5.13c SC1B5.13c - Streptomyces coelicolor
           >gi|3130017|emb|CAA18987.1| (AL023517) hypothetical
           protein SC1B5.13c [Streptomyces coelicolor A3(2)]
           Length = 262
           
 Score =  145 bits (361), Expect = 8e-34
 Identities = 88/273 (32%), Positives = 153/273 (55%), Gaps = 34/273 (12%)

Query: 24  SVKVIRPYQKGLVERLGKF-NRLLDPGIHFIIPFMERVKVVDLREHVIDVPPQEVICKDN 82
           + +V++ Y++G+V RLG+   +   PG   I+PF++R+  V+++   + VP QE I +DN
Sbjct: 23  AARVVKQYERGVVFRLGRLAGQARGPGFTMIVPFVDRLHKVNMQIITLPVPAQEGITRDN 82

Query: 83  VVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAK 142
           V V VDAVVY++++D   A+  V D+  A+ ++AQT+LR+IIG+ +LD+ LS R+ +N  
Sbjct: 83  VTVRVDAVVYFKVVDAANALVRVEDYRFAVSQMAQTSLRSIIGKSDLDDLLSDREKLNQG 142

Query: 143 LREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIR 202
           L   +D     WGV+I RVEI+ +  P  ++ +MA+Q  A+RE+RA ++ A+ + +A+  
Sbjct: 143 LELMIDSPAVGWGVQIDRVEIKDVSLPDTMKRSMARQAEADRERRARVINADAELQASKV 202

Query: 203 EAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEALKMADEKYLTLQYIEKLPDLAKY 262
            AE  ++ +   A              A  +R +   + +A EK  T             
Sbjct: 203 LAEAAREMSETPA--------------ALQLRLLQTVVAVAAEKNST------------- 235

Query: 263 GNLIVPYDTESLIGLLRVLQKVKSIPLQQSTEK 295
             L++P+  E    LLR L+K +  P++   E+
Sbjct: 236 --LVLPFPVE----LLRFLEKAQEHPVEHRVER 262


>sp|Q19200|STO1_CAEEL STO-1 PROTEIN >gi|7447613|pir||T15971 hypothetical protein F08C6.4
           - Caenorhabditis elegans >gi|868187|gb|AAA68723.1|
           (U29378) similar to erythrocyte band 7 integral membrane
           protein (SP:BAN7_HUMAN, P27105) [Caenorhabditis elegans]
           Length = 281
           
 Score =  141 bits (353), Expect = 7e-33
 Identities = 84/213 (39%), Positives = 127/213 (59%), Gaps = 6/213 (2%)

Query: 16  FLLIMLLLSVKV---IRPYQKGLVERLGKF-NRLLDPGIHFIIPFMERVKVVDLREHVID 71
           ++LI L   V V   I+ YQ+ +V RLG+    +  PGI FIIP ++    +DLR    +
Sbjct: 3   YVLIFLTFPVSVFMCIKEYQRAVVFRLGRLVPDVKGPGIFFIIPCIDTFLNIDLRVASYN 62

Query: 72  VPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDE 131
           VP QE++ +D+V V+VDAVVY+++ DP+ +V  V +   +   LAQT LR I+G   L E
Sbjct: 63  VPSQEILSRDSVTVSVDAVVYFKVFDPITSVVGVGNATDSTKLLAQTTLRTILGTHTLSE 122

Query: 132 TLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMIL 191
            LS R+ I+A ++  LD+ T+ WG+K+ RVE++ +  P  +Q AMA +  A R+  A I+
Sbjct: 123 ILSDREKISADMKISLDEATEPWGIKVERVELRDVRLPSQMQRAMAAEAEATRDAGAKII 182

Query: 192 IAEGKKEAAIREAEGQKQAAILKAEGEKQRQIL 224
            AEG+  A+   AE      I K+EG  Q + L
Sbjct: 183 AAEGELRASAALAEA--ATIISKSEGAMQLRYL 213


>sp|Q22165|STO4_CAEEL STO-4 PROTEIN
           Length = 213
           
 Score =  141 bits (352), Expect = 9e-33
 Identities = 76/177 (42%), Positives = 111/177 (61%), Gaps = 2/177 (1%)

Query: 26  KVIRPYQKGLVERLGKFNR--LLDPGIHFIIPFMERVKVVDLREHVIDVPPQEVICKDNV 83
           +V++ Y++ ++ RLG+        PGI FIIP +E  K +DLR    DVPPQE++ KD+V
Sbjct: 8   QVVQEYERAVIFRLGRLKHGGARGPGIFFIIPCIESFKKIDLRVVSFDVPPQEILSKDSV 67

Query: 84  VVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKL 143
            V+VDAV+Y++I +   +V NV D   +   LAQT LR  +G   L E LS RD I+ ++
Sbjct: 68  TVSVDAVIYFRISNATVSVINVEDAARSTKLLAQTTLRNFLGTRTLAEMLSSRDAISMQM 127

Query: 144 REELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAA 200
           +  LD+ TD WGVK+ RVEI+ +  P  +Q AMA +  A R   A I+ AEG++ A+
Sbjct: 128 QAALDEATDPWGVKVERVEIKDVRLPIQLQRAMAAEAEAARAAGAKIIAAEGEQLAS 184


>gb|AAF14646.1|AF163772_6 (AF163772) 7138.6 [Leishmania major]
           Length = 357
           
 Score =  141 bits (352), Expect = 9e-33
 Identities = 86/251 (34%), Positives = 137/251 (54%), Gaps = 18/251 (7%)

Query: 35  LVERLGKFNRLLDPGIHFIIPFMERVKV-VDLREHVIDVPPQEVICKDNVVVTVDAVVYY 93
           +VERLG+++R LD G   ++PF+++++   +++E  I++P Q  I  DNV+V +D V++ 
Sbjct: 72  VVERLGRYHRTLDSGWWVVVPFIDKIRYNYNVKEQGIEIPNQSAITSDNVMVEIDGVLFL 131

Query: 94  QILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKLREELDKITDR 153
           +I+D  KA YN+ + +  ++ LAQT +R+ IG M LD     R  +N    E L +  + 
Sbjct: 132 KIVDSCKASYNIENPVFNLINLAQTTMRSEIGRMSLDSLFRERASLNQSTVEVLRREANE 191

Query: 154 WGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQAAIL 213
           WG++  R EI+ I   + ++ +M  Q  AER+KR +IL +EG+  A I  A G K A   
Sbjct: 192 WGIECKRYEIRDIVVSELVRRSMDLQAEAERKKRKLILESEGESTATINRANGMKIAQQC 251

Query: 214 KAEGEKQRQILIAEGQAEAIR--------------KVLEALKMADEKY---LTLQYIEKL 256
            A+ EK      +EG A AIR                +E  K ++E     +   YIEK 
Sbjct: 252 VADAEKYTAERQSEGAAAAIRVKAAAVSDNISIVSDAIEKAKHSNEAISLRVAESYIEKF 311

Query: 257 PDLAKYGNLIV 267
            +LAK  N +V
Sbjct: 312 GELAKESNTVV 322


>gb|AAF54744.1| (AE003694) CG17424 gene product [Drosophila melanogaster]
           Length = 474
           
 Score =  141 bits (351), Expect = 1e-32
 Identities = 69/197 (35%), Positives = 124/197 (62%), Gaps = 4/197 (2%)

Query: 8   VALIILGIFLLIMLLLSV----KVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVV 63
           VA+ +  I +LI+L  S+     +   + + ++ RLG+    L PG+ F++P ++    V
Sbjct: 31  VAVFVSWILVLILLPFSLCCCLTIAYEFHRLVIFRLGRIRSCLGPGLVFLLPCIDSFNTV 90

Query: 64  DLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAI 123
           D+R  V++V PQE++ KD+V +TV+AVV+Y I DP+ ++  V D   A  +++Q  LR I
Sbjct: 91  DIRTDVVNVDPQEMLTKDSVSITVNAVVFYCIYDPINSIIKVDDARDATERISQVTLRNI 150

Query: 124 IGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAE 183
           +G   L E L+ R  ++ ++++ + KIT+RWGV++ RV++  I  P  ++ ++A +  A 
Sbjct: 151 VGSKGLHELLASRQQLSLEIQQAVAKITERWGVRVERVDLMEISLPSSLERSLASEAEAT 210

Query: 184 REKRAMILIAEGKKEAA 200
           RE RA I++AEG+ +A+
Sbjct: 211 REARAKIILAEGEAKAS 227


>sp|Q21190|UNC1_CAEEL UNC-1 PROTEIN >gi|7494583|pir||T34324 erythrocyte band 7 intergral
           membrane protein homolog unc-1 - Caenorhabditis elegans
           >gi|1280125|gb|AAC69044.1| (U55375) Erythrocyte band 7
           intergral membrane protein [Caenorhabditis elegans]
           Length = 282
           
 Score =  140 bits (350), Expect = 2e-32
 Identities = 84/213 (39%), Positives = 129/213 (60%), Gaps = 9/213 (4%)

Query: 7   GVALIILGIFLLIM-----LLLSVKVIRPYQKGLVERLGK--FNRLLDPGIHFIIPFMER 59
           G AL  L   L+I+     + + +KVI+ Y++ ++ R+G+  F     PG+ FIIP ++ 
Sbjct: 29  GYALQALSWILIIVTFPFSMCVCLKVIKEYERVVIFRIGRLVFGGARGPGMIFIIPCIDT 88

Query: 60  VKVVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTN 119
            + +DLR     VPPQE++ KD+V V+VDAVVY++  DP+ +V NV D + +   LAQT 
Sbjct: 89  YRKIDLRVVSYAVPPQEILSKDSVTVSVDAVVYFRTSDPIASVNNVDDAIYSTKLLAQTT 148

Query: 120 LRAIIGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQ 179
           LR  +G   L E L+ R+ I       LD+ T+ WGVK+ RVE++ I  P+ +  AMA +
Sbjct: 149 LRNALGMKTLTEMLTEREAIAQLCETILDEGTEHWGVKVERVEVKDIRLPQQLTRAMAAE 208

Query: 180 MTAEREKRAMILIAEGKKEA--AIREAEGQKQA 210
             A RE RA ++ AEG+++A  A++EA    QA
Sbjct: 209 AEAAREARAKVVAAEGEQKASRALKEAADVIQA 241


>pir||T27365 hypothetical protein Y71H9A.2 - Caenorhabditis elegans
           >gi|3881292|emb|CAA21750.1| (AL032659) predicted using
           Genefinder~contains similarity to Pfam domain: PF01145
           (SPFH domain / Band 7 family), Score=350.2,
           E-value=7.4e-102, N=1 [Caenorhabditis elegans]
           Length = 298
           
 Score =  140 bits (350), Expect = 2e-32
 Identities = 77/197 (39%), Positives = 119/197 (60%), Gaps = 2/197 (1%)

Query: 11  IILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNR--LLDPGIHFIIPFMERVKVVDLREH 68
           I+  + L I + L VKV + Y++ ++ RLG+        PG+ F++P ++  K +DLR  
Sbjct: 41  ILAVLTLPISVFLCVKVAQEYERAVIFRLGRVKPGGARGPGLFFVVPCIDSYKKIDLRTL 100

Query: 69  VIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEME 128
             +VPPQE++ KD V V VDAVV+++I +   +V N+ D   +   LAQT LR I+G   
Sbjct: 101 SFEVPPQELLSKDAVTVAVDAVVFFRISNATISVINIEDAARSTKLLAQTTLRNILGTKT 160

Query: 129 LDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRA 188
           L E LS RD+I+ +++  LD+ T  WGVK+ RVE++ +  P  +Q  MA +  A R+  A
Sbjct: 161 LTEMLSDRDVISLQMQATLDETTIPWGVKVERVEMKDVRLPYQLQRVMAAEAEATRDAMA 220

Query: 189 MILIAEGKKEAAIREAE 205
            I+ AEG+K A+   AE
Sbjct: 221 KIIAAEGEKNASTALAE 237


>gi|4758276 erythrocyte membrane protein band 7.2 (stomatin) [Homo sapiens]
           >gi|11427638|ref|XP_005343.1| erythrocyte membrane
           protein band 7.2 (stomatin) [Homo sapiens]
           >gi|114823|sp|P27105|BAN7_HUMAN ERYTHROCYTE BAND 7
           INTEGRAL MEMBRANE PROTEIN (STOMATIN) (PROTEIN 7.2B)
           >gi|88143|pir||S17659 membrane protein 7, erythrocyte -
           human >gi|31069|emb|CAA42671.1| (X60067) erythrocyte
           band 7 integral membrane  protein [Homo sapiens]
           >gi|1161562|emb|CAA59436.1| (X85116) stomatin [Homo
           sapiens] >gi|1586566|prf||2204264A band 7 integral
           membrane protein [Homo sapiens]
           Length = 288
           
 Score =  140 bits (349), Expect = 2e-32
 Identities = 73/190 (38%), Positives = 117/190 (61%), Gaps = 4/190 (2%)

Query: 19  IMLLLSVKVIRPYQKGLVERLGKFNR--LLDPGIHFIIPFMERVKVVDLREHVIDVPPQE 76
           I + + +K+I+ Y++ ++ RLG+  +     PG+ FI+P  +    VD+R    D+PPQE
Sbjct: 48  ISIWMCIKIIKEYERAIIFRLGRILQGGAKGPGLFFILPCTDSFIKVDMRTISFDIPPQE 107

Query: 77  VICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGR 136
           ++ KD+V ++VD VVYY++ +   AV N+++   A   LAQT LR ++G   L + LS R
Sbjct: 108 ILTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLLAQTTLRNVLGTKNLSQILSDR 167

Query: 137 DIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGK 196
           + I   ++  LD  TD WG+K+ RVEI+ +  P  +Q AMA +  A RE RA ++ AEG+
Sbjct: 168 EEIAHNMQSTLDDATDAWGIKVERVEIKDVKLPVQLQRAMAAEAEASREARAKVIAAEGE 227

Query: 197 KEA--AIREA 204
             A  A++EA
Sbjct: 228 MNASRALKEA 237


>gb|AAA58432.1| (M81635) stomatin peptide [Homo sapiens]
           Length = 288
           
 Score =  140 bits (349), Expect = 2e-32
 Identities = 73/190 (38%), Positives = 117/190 (61%), Gaps = 4/190 (2%)

Query: 19  IMLLLSVKVIRPYQKGLVERLGKFNR--LLDPGIHFIIPFMERVKVVDLREHVIDVPPQE 76
           I + + +K+I+ Y++ ++ RLG+  +     PG+ FI+P  +    VD+R    D+PPQE
Sbjct: 48  ISIWMCIKIIKEYERAIIFRLGRILQGGAKGPGLFFILPCTDSFIKVDMRTISFDIPPQE 107

Query: 77  VICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGR 136
           ++ KD+V ++VD VVYY++ +   AV N+++   A   LAQT LR ++G   L + LS R
Sbjct: 108 ILTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLLAQTTLRNVLGTKNLSQILSDR 167

Query: 137 DIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGK 196
           + I   ++  LD  TD WG+K+ RVEI+ +  P  +Q AMA +  A RE RA ++ AEG+
Sbjct: 168 EEIAHNMQSTLDDATDAWGIKVERVEIKDVKLPVQLQRAMAAEAEASREARAKVIAAEGE 227

Query: 197 KEA--AIREA 204
             A  A++EA
Sbjct: 228 MNASRALKEA 237


>gb|AAC50296.1| (U33931) band 7.2b stomatin [Homo sapiens]
           >gi|1585683|prf||2201444A membrane protein band 7.2b
           [Homo sapiens]
           Length = 296
           
 Score =  140 bits (349), Expect = 2e-32
 Identities = 73/190 (38%), Positives = 117/190 (61%), Gaps = 4/190 (2%)

Query: 19  IMLLLSVKVIRPYQKGLVERLGKFNR--LLDPGIHFIIPFMERVKVVDLREHVIDVPPQE 76
           I + + +K+I+ Y++ ++ RLG+  +     PG+ FI+P  +    VD+R    D+PPQE
Sbjct: 56  ISIWMCIKIIKEYERAIIFRLGRILQGGAKGPGLFFILPCTDSFIKVDMRTISFDIPPQE 115

Query: 77  VICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGR 136
           ++ KD+V ++VD VVYY++ +   AV N+++   A   LAQT LR ++G   L + LS R
Sbjct: 116 ILTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLLAQTTLRNVLGTKNLSQILSDR 175

Query: 137 DIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGK 196
           + I   ++  LD  TD WG+K+ RVEI+ +  P  +Q AMA +  A RE RA ++ AEG+
Sbjct: 176 EEIAHNMQSTLDDATDAWGIKVERVEIKDVKLPVQLQRAMAAEAEASREARAKVIAAEGE 235

Query: 197 KEA--AIREA 204
             A  A++EA
Sbjct: 236 MNASRALKEA 245


>sp|P54116|BAN7_MOUSE ERYTHROCYTE BAND 7 INTEGRAL MEMBRANE PROTEIN (STOMATIN) (PROTEIN
           7.2B)
           Length = 284
           
 Score =  139 bits (346), Expect = 5e-32
 Identities = 78/209 (37%), Positives = 125/209 (59%), Gaps = 8/209 (3%)

Query: 4   SAGGVALIILGIFLLIMLLLSV----KVIRPYQKGLVERLGKFNR--LLDPGIHFIIPFM 57
           + G + + +  IF+LI   +S+    K+++ Y++ ++ RLG+  +     PG+ FI+P  
Sbjct: 29  ACGWILVAVSFIFVLITFPISIWICIKIVKEYERVIIFRLGRILQGGAKGPGLFFILPCT 88

Query: 58  ERVKVVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQ 117
           +    VD+R    D+PPQEV+ KD+V ++VD VVYY++ +   AV N+++   A   LAQ
Sbjct: 89  DSFIKVDMRTISFDIPPQEVLTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLLAQ 148

Query: 118 TNLRAIIGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMA 177
           T LR  +G   L + LS R+ I   ++  LD  TD WG+K+ RVEI+ +  P  +Q AMA
Sbjct: 149 TTLRNALGTKNLSQILSDREEIAHHMQSTLDDATDDWGIKVERVEIKDVKLPVQLQRAMA 208

Query: 178 KQMTAEREKRAMILIAEGKKEA--AIREA 204
            +  A RE RA ++ AEG+  A  A++EA
Sbjct: 209 AEAEAAREARAKVIAAEGEMNASRALKEA 237


>pir||JC5221 stomatin - mouse >gi|975689|emb|CAA62503.1| (X91043) erthyrocyte
           band 7 integral membrane protein, protein 7.2B, stomatin
           [Mus musculus]
           Length = 284
           
 Score =  139 bits (346), Expect = 5e-32
 Identities = 78/209 (37%), Positives = 125/209 (59%), Gaps = 8/209 (3%)

Query: 4   SAGGVALIILGIFLLIMLLLSV----KVIRPYQKGLVERLGKFNR--LLDPGIHFIIPFM 57
           + G + + +  IF+LI   +S+    K+++ Y++ ++ RLG+  +     PG+ FI+P  
Sbjct: 29  ACGWILVAVSFIFVLITFPISIWICIKIVKEYERVIIFRLGRILQGGAKGPGLFFILPCT 88

Query: 58  ERVKVVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQ 117
           +    VD+R    D+PPQEV+ KD+V ++VD VVYY++ +   AV N+++   A   LAQ
Sbjct: 89  DSFIKVDMRTISFDIPPQEVLTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLLAQ 148

Query: 118 TNLRAIIGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMA 177
           T LR  +G   L + LS R+ I   ++  LD  TD WG+K+ RVEI+ +  P  +Q AMA
Sbjct: 149 TTLRNALGTKNLSQILSDREEIAHHMQSTLDDATDDWGIKVERVEIKDVKLPVQLQRAMA 208

Query: 178 KQMTAEREKRAMILIAEGKKEA--AIREA 204
            +  A RE RA ++ AEG+  A  A++EA
Sbjct: 209 AEAEAAREARAKVIAAEGEMNASRALKEA 237


>sp|Q19958|STO2_CAEEL STO-2 PROTEIN >gi|7500297|pir||T16240 hypothetical protein F32A6.5
           - Caenorhabditis elegans >gi|1065452|gb|AAA81390.1|
           (U40409) similar C. elegans stomatin-like protein MEC-2,
           Genbank accession # U26735, and to erythrocyte band 7
           integral membrane protein SP:BAN7_HUMAN [Caenorhabditis
           elegans]
           Length = 280
           
 Score =  139 bits (346), Expect = 5e-32
 Identities = 76/202 (37%), Positives = 124/202 (60%), Gaps = 4/202 (1%)

Query: 7   GVALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKF--NRLLDPGIHFIIPFMERVKVVD 64
           G++ I++     + +   +KV++ Y++ ++ RLG+        PGI F++P +E    VD
Sbjct: 41  GLSWIMVISTFPVSIYFCMKVVQEYERAVIFRLGRLIGGGAKGPGIFFVLPCIESYTKVD 100

Query: 65  LREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAII 124
           LR     VPPQE++ KD+V  +VDAV+YY+I +   +V NV +   +   LAQT LR ++
Sbjct: 101 LRTVSFSVPPQEILTKDSVTTSVDAVIYYRISNATVSVANVENAHHSTRLLAQTTLRNML 160

Query: 125 GEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAER 184
           G   L E LS R+ + A ++  LD+ T+ WG+K+ RVEI+ +  P  +Q AMA +  A R
Sbjct: 161 GTRSLSEILSDRETLAASMQTILDEATESWGIKVERVEIKDVRLPIQLQRAMAAEAEATR 220

Query: 185 EKRAMILIAEGKKEA--AIREA 204
           E RA ++ AEG+++A  A+R+A
Sbjct: 221 EARAKVIAAEGEQKASRALRDA 242


>gi|7710018 erythrocyte protein band 7.2; protein 7.2b [Mus musculus]
           >gi|972907|gb|AAA75024.1| (U17297) integral membrane
           phosphoprotein band 7.2b [Mus musculus]
           >gi|1582614|prf||2119189A band 7.2b protein [Mus
           musculus]
           Length = 284
           
 Score =  138 bits (344), Expect = 8e-32
 Identities = 77/211 (36%), Positives = 125/211 (58%), Gaps = 9/211 (4%)

Query: 3   ISAGGVALIILGIFLLIM-----LLLSVKVIRPYQKGLVERLGKFNR--LLDPGIHFIIP 55
           + A G  L+    F +I+     + + +K+++ Y++ ++ RLG+  +     PG+ FI+P
Sbjct: 27  LGACGWILVAASFFFVIITFPISIWICIKIVKEYERVIIFRLGRILQGGAKGPGLFFILP 86

Query: 56  FMERVKVVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKL 115
             + +  VD+R    D+PPQEV+ KD+V ++VD VVYY++ +   AV N+++   A   L
Sbjct: 87  CTDSLIKVDMRTISFDIPPQEVLTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLL 146

Query: 116 AQTNLRAIIGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEA 175
           AQT LR  +G   L + LS R+ I   ++  LD  TD WG+K+ RVEI+ +  P  +Q A
Sbjct: 147 AQTTLRNALGTKNLSQILSDREEIAHHMQSTLDDATDDWGIKVERVEIKDVKLPVQLQRA 206

Query: 176 MAKQMTAEREKRAMILIAEGKKEA--AIREA 204
           MA +  A RE RA ++ AEG+  A  A++EA
Sbjct: 207 MAAEAEAAREARAKVIAAEGEMNASRALKEA 237


>gb|AAC64173.1| (AF093620) stomatin [Mus musculus]
           Length = 284
           
 Score =  138 bits (344), Expect = 8e-32
 Identities = 77/211 (36%), Positives = 125/211 (58%), Gaps = 9/211 (4%)

Query: 3   ISAGGVALIILGIFLLIM-----LLLSVKVIRPYQKGLVERLGKFNR--LLDPGIHFIIP 55
           + A G  L+    F +I+     + + +K+++ Y++ ++ RLG+  +     PG+ FI+P
Sbjct: 27  LGACGWILVAASFFFVIITFPISIWICIKIVKEYERVIIFRLGRILQGGAKGPGLFFILP 86

Query: 56  FMERVKVVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKL 115
             + +  VD+R    D+PPQEV+ KD+V ++VD VVYY++ +   AV N+++   A   L
Sbjct: 87  CTDSLIKVDMRTISFDIPPQEVLTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLL 146

Query: 116 AQTNLRAIIGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEA 175
           AQT LR  +G   L + LS R+ I   ++  LD  TD WG+K+ RVEI+ +  P  +Q A
Sbjct: 147 AQTTLRNALGTKNLSQILSDREEIAHHMQSTLDDATDDWGIKVERVEIKDVKLPVQLQRA 206

Query: 176 MAKQMTAEREKRAMILIAEGKKEA--AIREA 204
           MA +  A RE RA ++ AEG+  A  A++EA
Sbjct: 207 MAAEAEAAREARAKVIAAEGEMNASRALKEA 237


>sp|Q20657|STO3_CAEEL STO-3 PROTEIN >gi|7503947|pir||T22502 hypothetical protein F52D10.5
           - Caenorhabditis elegans >gi|3877420|emb|CAA91476.1|
           (Z66564) contains similarity to Pfam domain: PF01145
           (SPFH domain / Band 7 family), Score=393.1,
           E-value=8.8e-115, N=1 [Caenorhabditis elegans]
           Length = 267
           
 Score =  130 bits (323), Expect = 2e-29
 Identities = 73/200 (36%), Positives = 123/200 (61%), Gaps = 6/200 (3%)

Query: 8   VALIILGIFLLIMLLLS----VKVIRPYQKGLVERLGKF--NRLLDPGIHFIIPFMERVK 61
           VALI    FLL+   +S    VK+++ Y + ++ RLG+   +    PGI  ++PF++  K
Sbjct: 18  VALICAWAFLLLTFPVSIFFCVKIVKEYDRMVIFRLGRLWQDNPRGPGIVLVLPFIDSHK 77

Query: 62  VVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLR 121
            VDLR    DVP QE++ +D+V + VDA VYY+  DP+ ++  V+D  M+  +LAQ++LR
Sbjct: 78  TVDLRVMSYDVPTQEMLTRDSVTIGVDAAVYYRTSDPIASLARVNDAHMSTRQLAQSSLR 137

Query: 122 AIIGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMT 181
            ++G   L E ++ R  I  +++  LD  T  WG+ + RVEI+ I  P+++  AMA +  
Sbjct: 138 NVLGTRSLAELMTDRHGIAVQVKYILDSATLFWGIHVERVEIKDIRLPREMCRAMAAEAE 197

Query: 182 AEREKRAMILIAEGKKEAAI 201
           A+RE  A ++ A+G+ +A++
Sbjct: 198 AQRESDAKVVTAQGELDASM 217


>gb|AAF54746.1| (AE003694) CG14736 gene product [Drosophila melanogaster]
           Length = 368
           
 Score =  122 bits (304), Expect = 4e-27
 Identities = 64/173 (36%), Positives = 109/173 (62%), Gaps = 3/173 (1%)

Query: 35  LVERLGKFNR-LLDPGIHFIIPFMERVKVVDLREHVIDVPPQEVICKDNVVVTVDAVVYY 93
           ++ RLG+  + L  PG+ FI+P ++    VD+R  V +V PQ+V+ KD+V +TV+AVVYY
Sbjct: 2   IILRLGRLRKGLRGPGLVFILPCIDETHRVDMRTDVTNVRPQDVLTKDSVTITVNAVVYY 61

Query: 94  QILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKLREELDKITDR 153
            I  P+ ++  V D   A   ++Q  LR I+G   L+  L+ R  ++ ++++ +  IT R
Sbjct: 62  CIYSPIDSIIQVDDAKQATQLISQVTLRNIVGSKTLNVLLTSRQQLSREIQQAVAGITYR 121

Query: 154 WGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEA--AIREA 204
           WGV++ RV++  I  P  ++ ++A +  A RE RA I++AEG+ +A  A++EA
Sbjct: 122 WGVRVERVDVMDITLPTSLERSLASEAEAVREARAKIILAEGELKASKALKEA 174


>gb|AAF52157.1| (AE003607) CG14644 gene product [Drosophila melanogaster]
           Length = 225
           
 Score =  113 bits (279), Expect = 3e-24
 Identities = 60/178 (33%), Positives = 106/178 (58%), Gaps = 4/178 (2%)

Query: 31  YQKGLVERLGKFNRL--LDPGIHFIIPFMERVKVVDLREHVIDVPPQEVICKDNVVVTVD 88
           Y++ ++ RLG+        PG+ F++P ++ + VVD+R    D+  QE++ +D V +++D
Sbjct: 4   YERAVILRLGRLRPKPPRGPGVIFLVPCIDDLAVVDIRTRSFDLHRQEILTRDMVTISID 63

Query: 89  AVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKLREELD 148
            VVYY I  P  A+  V D   A  KLA T LR + G  +L + LS ++ ++ ++   L 
Sbjct: 64  GVVYYSIKSPFDAMLQVYDPEEATEKLAMTTLRNVAGTHKLMDLLSSKEYLSNQIEGILY 123

Query: 149 KITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEA--AIREA 204
             T+ WG+++ RVEI+ I  P  ++ A+A +  A RE +A +  A+G+++A  A++EA
Sbjct: 124 NSTEPWGIRVERVEIKEIFMPDQLKRALAVEQEAMREAKAKVAAAQGERDAVTALKEA 181


>gi|7657615 podocin [Homo sapiens] >gi|7363002|emb|CAB83216.1| (AJ279254)
           podocin [Homo sapiens] >gi|7363472|emb|CAB83272.1|
           (AJ279246) podocin [Homo sapiens]
           Length = 383
           
 Score =  106 bits (261), Expect = 4e-22
 Identities = 54/198 (27%), Positives = 109/198 (54%), Gaps = 7/198 (3%)

Query: 10  LIILGIFLLIM-----LLLSVKVIRPYQKGLVERLGKF--NRLLDPGIHFIIPFMERVKV 62
           L+++ +  +IM     +   VKV++ Y++ ++ RLG     R   PG+ F +P ++    
Sbjct: 105 LVLISLLFIIMTFPFSIWFCVKVVQEYERVIIFRLGHLLPGRAKGPGLFFFLPCLDTYHK 164

Query: 63  VDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRA 122
           VDLR   +++P  E++ KD  ++ +DA+ YY++ +    + +++    A+  L QT ++ 
Sbjct: 165 VDLRLQTLEIPFHEIVTKDMFIMEIDAICYYRMENASLLLSSLAHVSKAVQFLVQTTMKR 224

Query: 123 IIGEMELDETLSGRDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTA 182
           ++    L E L  R  I    +  LD +T  WG+K+ R+EI+ +  P  +Q ++A +  A
Sbjct: 225 LLAHRSLTEILLERKSIAQDAKVALDSVTCIWGIKVERIEIKDVRLPAGLQHSLAVEAEA 284

Query: 183 EREKRAMILIAEGKKEAA 200
           +R+ +  ++ AE +K A+
Sbjct: 285 QRQAKVRMIAAEAEKAAS 302


>pir||E82334 hflK protein VC0349 [imported] - Vibrio cholerae (group O1 strain
           N16961) >gi|9654765|gb|AAF93522.1| (AE004123) hflK
           protein [Vibrio cholerae]
           Length = 395
           
 Score =  102 bits (251), Expect = 6e-21
 Identities = 78/281 (27%), Positives = 141/281 (49%), Gaps = 9/281 (3%)

Query: 5   AGGVAL---IILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVK 61
           +GG A+   +I  I + +        I   ++G+V RLGK++R++DPG+++   F++ V 
Sbjct: 64  SGGGAIGFGVIAAIAVAVWFFTGFYTIGEAERGVVLRLGKYDRIVDPGLNWRPRFIDEVT 123

Query: 62  VVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLR 121
            V+++          ++ KD  VVTV   V Y+I DP K +Y V++   ++ +   + LR
Sbjct: 124 PVNVQAIRSLRASGLMLTKDENVVTVSMDVQYRIADPYKYLYRVTNADDSLRQATDSALR 183

Query: 122 AIIGEMELDETL-SGRDIINAKLREELDKITDRW--GVKITRVEIQRIDPPKDIQEAMAK 178
           A++G+  +D  L SGR  I    ++ L+++ D +  G+ I  V  Q   PP+ +++A   
Sbjct: 184 AVVGDSLMDSILTSGRQQIRQSTQQTLNQVIDSYDMGLMIVDVNFQSARPPEQVKDAFDD 243

Query: 179 QMTAEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLE 238
            + A  ++   I  AE  K   + +A G+ +    +A+G  +R I  A GQ     K+L 
Sbjct: 244 AIAAREDEERFIREAEAYKNEILPKATGRAERLKKEAQGYNERTINEALGQVAQFEKLLP 303

Query: 239 ALKMADEKYLTLQYIEKLPDLAKYGNLI-VPYDTESLIGLL 278
             + A +      Y++ +  +  Y N   V  D+ES   LL
Sbjct: 304 EYQAAPKVTRDRLYLDAMEQV--YSNTSKVLIDSESSGNLL 342


>sp|P40605|HFLK_VIBPA HFLK PROTEIN >gi|507734|gb|AAA62186.1| (U09005) HflK [Vibrio
           parahaemolyticus]
           Length = 400
           
 Score =  101 bits (249), Expect = 1e-20
 Identities = 84/302 (27%), Positives = 150/302 (48%), Gaps = 10/302 (3%)

Query: 3   ISAGGVAL---IILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMER 59
           I  GG A+   +I  I + + +      I   ++G+V RLGK++R++DPG+++   F++ 
Sbjct: 65  IGGGGGAIGFGVIAIIAIAVWIFAGFYTIGEAERGVVLRLGKYDRIVDPGLNWRPRFIDE 124

Query: 60  VKVVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTN 119
            + V+++          ++ KD  VVTV   V Y++ DP K +Y V++   ++ +   + 
Sbjct: 125 YEAVNVQAIRSLRASGLMLTKDENVVTVAMDVQYRVADPYKYLYRVTNADDSLRQATDSA 184

Query: 120 LRAIIGEMELDETL-SGRDIINAKLREELDKITDRW--GVKITRVEIQRIDPPKDIQEAM 176
           LRA+IG+  +D  L SGR  I    +E L++I D +  G+ I  V  Q   PP+ +++A 
Sbjct: 185 LRAVIGDSLMDSILTSGRQQIRQSTQETLNQIIDSYDMGLVIVDVNFQSARPPEQVKDAF 244

Query: 177 AKQMTAEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKV 236
              + A  ++   I  AE  K   + +A G+ +    +A+G  +R    A GQ     K+
Sbjct: 245 DDAIAAREDEERFIREAEAYKNEILPKATGRAERLKKEAQGYNERVTNEALGQVAQFEKL 304

Query: 237 LEALKMADEKYLTLQYIEKLPDLAKYGNLI-VPYDTESLIGLLRV-LQKVKSIPLQQSTE 294
           L   + A        YI+ + ++  Y N   V  D+ES   LL + + K+     Q  T+
Sbjct: 305 LPEYQAAPGVTRDRLYIDAMEEV--YTNTSKVLIDSESSGNLLYLPIDKLAGQEGQTDTK 362

Query: 295 KK 296
           +K
Sbjct: 363 RK 364


>gb|AAB18857.1| (U50999) stomatin [Mus musculus]
           Length = 259
           
 Score =  100 bits (247), Expect = 2e-20
 Identities = 64/185 (34%), Positives = 101/185 (54%), Gaps = 15/185 (8%)

Query: 24  SVKVIRPYQKGLVERLGKFNR--LLDPGIHFIIPFMERVKVVDLREHVIDVPPQEVICKD 81
           S  +++ Y++ ++ RLG+  +     PG+ F+     R      R          V+ KD
Sbjct: 39  SFSIVKEYERVIIFRLGRILQGGAKGPGVCFLSC---RALTASSR--------WTVLTKD 87

Query: 82  NVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINA 141
           +V ++VD VVYY++ +   AV N+++   A   LAQT LR  +G   L + LS R+ I  
Sbjct: 88  SVTISVDGVVYYRVQNATLAVANITNADSATRLLAQTTLRNALGTKNLSQILSDREEIAH 147

Query: 142 KLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEA-- 199
            ++  LD  TD WG+K+ RVEI+ +  P  +Q AMA +  A RE RA ++ AEG+  A  
Sbjct: 148 HMQSTLDDATDDWGIKVERVEIKDVKLPVQLQRAMAAEAEAAREARAKVIAAEGEMNASR 207

Query: 200 AIREA 204
           A++EA
Sbjct: 208 ALKEA 212


>pir||B72207 ftsH proteinase activity modulator HflC - Thermotoga maritima
           (strain MSB8) >gi|4982405|gb|AAD36886.1|AE001819_9
           (AE001819) ftsH protease activity modulator HflC
           [Thermotoga maritima]
           Length = 283
           
 Score =  100 bits (247), Expect = 2e-20
 Identities = 75/271 (27%), Positives = 139/271 (50%), Gaps = 8/271 (2%)

Query: 10  LIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRL-LDPGIHFIIPFMERVKVVDLREH 68
           LIIL +   I+L  S  V+   Q+ +V R GK   +  +PG+HF  PF++ V   D R  
Sbjct: 9   LIILIVVGAILLFSSFYVLDQTQQAVVLRFGKIVAVETEPGLHFKQPFVDNVVRFDKRIL 68

Query: 69  VIDVPPQEVICKDNVVVTVDAVVYYQILDP---VKAVYNVSDFLMAIVKLAQTNLRAIIG 125
           + D+ P+++I  D   + +D  V ++I D    +K++ +V   L  I  +  +++R I  
Sbjct: 69  LYDIEPEKIIAADKKTLVIDTYVLWRIKDAEAFIKSLKSVKLALPRIDDVVYSHVRNIFA 128

Query: 126 EMELDETLSGR--DIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAE 183
           +   DE +S +  D++        + + D +G+++  V ++  D P + ++A+ ++M AE
Sbjct: 129 KANFDEIISEKREDLLREVTALSREDLKD-FGIEVVDVRVKHADLPAENEKAVYERMKAE 187

Query: 184 REKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEALKMA 243
           R   A  + AEG+KEA    AE  K A +L AE + + + +   G+A A++   E     
Sbjct: 188 RYSIAAQIRAEGEKEARKIRAEADKTAKVLIAEAQSKAEQIKGTGEASAVKIYAEVFSKD 247

Query: 244 DEKYLTLQYIEKLPDLAKYGNLIVPYDTESL 274
            + Y   + +E    + K G LI+  + ++L
Sbjct: 248 KDFYEFWRTMEVYRSIEK-GILIIGDELDAL 277


>pir||A82806 integral membrane proteinase XF0452 [imported] - Xylella fastidiosa
           (strain 9a5c) >gi|9105296|gb|AAF83262.1|AE003895_13
           (AE003895) integral membrane protease [Xylella
           fastidiosa]
           Length = 379
           
 Score = 99.1 bits (243), Expect = 6e-20
 Identities = 72/280 (25%), Positives = 137/280 (48%), Gaps = 10/280 (3%)

Query: 2   MISAGGVALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPF----M 57
           +  AG +  +++G+ LLI++  S+++I   Q+G+V R G+F R+L PG+   +P+    +
Sbjct: 43  LFDAGILIWVLIGV-LLIVVFSSIQLIGEQQRGVVLRFGQFVRVLQPGLSLKLPWPVESV 101

Query: 58  ERVKVVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQ 117
            +V   +++     VP   V+ +D  +V V   V YQI DP   +Y   +    +V+ AQ
Sbjct: 102 YKVNATEIKTFGKQVP---VLTRDENIVNVTLNVQYQINDPHLYLYGSRNANEVLVQAAQ 158

Query: 118 TNLRAIIGEMELDETLSGRDIINAKLREELDKITD--RWGVKITRVEIQRIDPPKDIQEA 175
           + +R  +G  +L+  L+ R  ++   +E L    D  R G+ +T + +    PP++++ A
Sbjct: 159 SAVREQVGRSDLNSVLNNRGPLSTASKERLQASLDAYRTGLLVTGLTLPDARPPEEVKSA 218

Query: 176 MAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRK 235
             +   A++ +  +I  A+      + EA G+  +    AEG KQ  I  A+G A+    
Sbjct: 219 FDEVNGAQQVRERLIDEAQAYAAKVVPEARGRAASNRTAAEGYKQAVIARAQGDADRFTL 278

Query: 236 VLEALKMADEKYLTLQYIEKLPDLAKYGNLIVPYDTESLI 275
           +    K A E      ++E +  +      ++  D   LI
Sbjct: 279 LQAQYKNAPEVTRKRLWLETIQQVLAQNRKVIGADGRQLI 318


>sp|P25662|HFLK_ECOLI HFLK PROTEIN >gi|280067|pir||B43653 probable integral membrane
           proteinase (EC 3.4.-.-) hflK - Escherichia coli
           >gi|436157|gb|AAC43399.1| (U00005) putative integral
           membrane protein required for high frequency
           lysogenization by bacteriophage lambda [Escherichia
           coli] >gi|537015|gb|AAA97070.1| (U14003) CG Site No.
           639; alternate gene name hflA; putative integral
           membrane protease required for high frequency
           lysogenization by bacteriophage lambda [Escherichia
           coli] >gi|1790616|gb|AAC77131.1| (AE000489) protease
           specific for phage lambda cII repressor [Escherichia
           coli K12]
           Length = 419
           
 Score = 97.1 bits (238), Expect = 2e-19
 Identities = 70/255 (27%), Positives = 128/255 (49%), Gaps = 5/255 (1%)

Query: 6   GGVALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVVDL 65
           G V  I     ++I        I+  ++G+V R GKF+ L++PG+++   F++ VK V++
Sbjct: 78  GRVVTIAAAAIVIIWAASGFYTIKEAERGVVTRFGKFSHLVEPGLNWKPTFIDEVKPVNV 137

Query: 66  REHVIDVPPQEV-ICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAII 124
            E V ++    V +  D  VV V+  V Y++ +P K +Y+V+    ++ +   + LR +I
Sbjct: 138 -EAVRELAASGVMLTSDENVVRVEMNVQYRVTNPEKYLYSVTSPDDSLRQATDSALRGVI 196

Query: 125 GEMELDETLS-GRDIINAKLREELDKITDRWGVKITRVEI--QRIDPPKDIQEAMAKQMT 181
           G+  +D  L+ GR +I +  + EL++    + + IT +++  Q   PP++++ A    + 
Sbjct: 197 GKYTMDRILTEGRTVIRSDTQRELEETIRPYDMGITLLDVNFQAARPPEEVKAAFDDAIA 256

Query: 182 AEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEALK 241
           A   ++  I  AE         A GQ Q  + +A   K + IL A+G+     K+L   K
Sbjct: 257 ARENEQQYIREAEAYTNEVQPRANGQAQRILEEARAYKAQTILEAQGEVARFAKLLPEYK 316

Query: 242 MADEKYLTLQYIEKL 256
            A E      YIE +
Sbjct: 317 AAPEITRERLYIETM 331


>pir||B83028 proteinase subunit HflK PA4942 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9951222|gb|AAG08327.1|AE004907_5
           (AE004907) protease subunit HflK [Pseudomonas
           aeruginosa]
           Length = 400
           
 Score = 97.1 bits (238), Expect = 2e-19
 Identities = 65/259 (25%), Positives = 130/259 (50%), Gaps = 5/259 (1%)

Query: 6   GGVALIILGIFLLIMLLL--SVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVV 63
           GG+ L  +G+ +L +L L  ++ V+   ++ ++ R GK+   + PG++F  P +++    
Sbjct: 71  GGLGLFGIGLAILAVLWLYNAIYVVDEQEQAVILRFGKYYETVGPGLNFYFPPIDKRFQE 130

Query: 64  DLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAI 123
           ++          +++ +D  +V V   V Y+I +    V NV    +++ +  ++ LR +
Sbjct: 131 NVTRERAYSKQGQMLTEDENIVEVPLTVQYKISNLQDFVLNVDQPEVSLQQATESALRHV 190

Query: 124 IGEMELDETLS-GRDIINAKLREELDKITD--RWGVKITRVEIQRIDPPKDIQEAMAKQM 180
            G   +D  L+ GR+ +  ++RE L +  D  R G+ +T+V IQ    P+++QEA    +
Sbjct: 191 AGSTTMDRILTEGREQMATEVRERLQRFLDTYRTGITVTQVNIQSAQAPREVQEAFDDVI 250

Query: 181 TAEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEAL 240
            A  +++     AE      + EA GQ Q  I +A G +   I  A+G+A+   K+L   
Sbjct: 251 RAREDEQREKNQAEAYANGVVPEARGQAQRIIEEANGYRDEVISRAQGEADRFSKLLVEY 310

Query: 241 KMADEKYLTLQYIEKLPDL 259
           + A E      Y++ + ++
Sbjct: 311 RKAPEVTRERLYLDTMQEV 329


>pir||A72207 ftsH proteinase activity modulator HflK - Thermotoga maritima
           (strain MSB8) >gi|4982404|gb|AAD36885.1|AE001819_8
           (AE001819) ftsH protease activity modulator HflK
           [Thermotoga maritima]
           Length = 308
           
 Score = 96.7 bits (237), Expect = 3e-19
 Identities = 82/305 (26%), Positives = 143/305 (46%), Gaps = 31/305 (10%)

Query: 8   VALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMER----VKVV 63
           V  I+LGI+ L      V  + P +  L++  G+F  ++  GIH+ +P+  +    V V 
Sbjct: 8   VVFIVLGIYFLT----GVYQVGPSEVALLKTFGRFTSVVPSGIHYHLPYPIQSHVTVDVT 63

Query: 64  DLREHVI-------------DVPPQE--VICKDNVVVTVDAVVYYQILDPVKAVYNVSDF 108
            +R+  I                PQE  +I  DN +V+V+AVV Y++ DPV   +N+++ 
Sbjct: 64  TVRKIEIGFRSIQRGERISYQSVPQEAIMITGDNNLVSVEAVVQYRVKDPVAYAFNITEA 123

Query: 109 LMAIVKLAQTNLRAIIGEMELDETL-SGRDIINAKLREELDKITDRW--GVKITRVEIQR 165
              +    ++ LR  +    +D+ L SGRD I  K  + L +I D +  G+K+  V +Q 
Sbjct: 124 DSIVRFTTESVLREKVAMRSIDDVLTSGRDEIGFKTAQMLQEILDSYNCGIKVENVYLQE 183

Query: 166 IDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILI 225
           + PP  + +A      A ++K  +I  A       + +A+GQ Q  + +AE   Q   L 
Sbjct: 184 VVPPDPVVDAFDDVNNARQDKERLINEARKYANDVVPKAQGQAQEILRQAEAYAQEVYLK 243

Query: 226 AEGQAEAIRKVLEALKMADE---KYLTLQYIEKLPDLAKYGNLIVPYDTESLIGLLRVLQ 282
           A G+A+   +VLE    A +   K + L  ++ L  L K  N +        + +L +  
Sbjct: 244 ALGEAKRFEEVLEEYSKAPDITRKRMLLDALQSL--LEKSENKVFFVGNGDSLNILNISD 301

Query: 283 KVKSI 287
            +K +
Sbjct: 302 LLKGM 306


>dbj|BAB06873.1| (AP001517) protease specific for phage lambda cII repressor
           [Bacillus halodurans]
           Length = 310
           
 Score = 95.2 bits (233), Expect = 8e-19
 Identities = 73/289 (25%), Positives = 144/289 (49%), Gaps = 24/289 (8%)

Query: 3   ISAGGVALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRL-LDPGIHFIIPFMERVK 61
           +  G VA++++GI  +I  L ++ ++   +  +V + G+  R+  +PG+ F IPF++ V 
Sbjct: 22  VQLGSVAVLLIGIVGII--LSNLFIVEQGEYKVVRQFGEVVRVESEPGLKFKIPFIQSVS 79

Query: 62  VVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQ---T 118
            +   + + D+PP E+  +D   +  D    ++I DP++ + NV     A   L +   +
Sbjct: 80  TLPKYQMIYDIPPAEINTRDKKRMMADHYALWRIEDPLRMISNVGSLQGAEAILGEQIFS 139

Query: 119 NLRAIIGEMELDETL----SGRDIINAKLREELDKITDR--WGVKITRVEIQRIDPPKDI 172
            +RA +G++E  E +    + R   N +++E ++   +R   G+ +  V ++R D PK+ 
Sbjct: 140 AIRAELGQLEFGEIINEEENSRGDFNQQVKERVNSSLERQDLGIVLLDVRMKRTDLPKEN 199

Query: 173 QEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEA 232
           +EA+ ++M +ERE  A   +++G  EA    A   ++   + A+ +   + +I  G+AEA
Sbjct: 200 EEAVYRRMISERESIAQDYLSQGDAEANRIRARTDQEVTEILAKAKADAEEIIGAGEAEA 259

Query: 233 IRKVLEALKMADE---KYLTLQYIEK---------LPDLAKYGNLIVPY 269
                E+     E    Y TL   EK         LP  + Y  +++ Y
Sbjct: 260 AEIYNESFGRDPEFYQLYRTLLSYEKTIGDQTVIVLPADSPYARILMGY 308


>pir||A71722 hflC protein (hflC) RP123 - Rickettsia prowazekii
           >gi|3860691|emb|CAA14592.1| (AJ235270) HFLC PROTEIN
           (hflC) [Rickettsia prowazekii]
           Length = 286
           
 Score = 94.0 bits (230), Expect = 2e-18
 Identities = 72/270 (26%), Positives = 133/270 (48%), Gaps = 14/270 (5%)

Query: 11  IILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLD-PGIHFIIPFMERVKVVDLREHV 69
           I+ G+ L+   L SV      Q  +V + G+  R ++ PG++  IPF++ V+  D R   
Sbjct: 12  IVFGLMLIASALFSVD---QRQSAVVFQFGEAIRTIENPGLNIKIPFIQNVEFFDKRLLD 68

Query: 70  IDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLA---QTNLRAIIGE 126
           ++V  +E+   D   V VDA   +QI +PV     V D+    ++L    ++++R +IG+
Sbjct: 69  VEVEAKELTAADGKRVIVDAYAKFQINNPVMFYKTVHDYQGVKIRLTRNLESSMRKVIGK 128

Query: 127 MELDETLSG-RDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAERE 185
           + L   LS  R  +   +  +++     +G+ +  V I R D PK+   A+ ++M   RE
Sbjct: 129 ISLSSLLSQERSNVMLNILNQVNGEAKSFGIDVVDVRILRADLPKENSAAIYRRMQTARE 188

Query: 186 KRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEALKMADE 245
           K A  + AEG++E+    ++  K++ I+ A+  +  QI+  +G  +A  K+  A    D 
Sbjct: 189 KEATQIRAEGQEESVRIRSKADKESKIILAKAYRDAQIIKGDGDEKA-AKIYNAAYSVDP 247

Query: 246 KYLTLQYIEKLPDLAKYGNLIVPYDTESLI 275
                ++ +    L  Y N +   DT  +I
Sbjct: 248 -----EFYKFYRSLLVYKNALKKEDTNFVI 272


>pir||A83028 proteinase subunit HflC PA4941 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9951221|gb|AAG08326.1|AE004907_4
           (AE004907) protease subunit HflC [Pseudomonas
           aeruginosa]
           Length = 289
           
 Score = 92.4 bits (226), Expect = 5e-18
 Identities = 60/230 (26%), Positives = 121/230 (52%), Gaps = 20/230 (8%)

Query: 11  IILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRL-LDPGIHFIIPFMERVKVVDLREHV 69
           +I+G+   I+L  SV V++  ++ ++ R G+     + PG+HF IP++ +V+  D R   
Sbjct: 9   LIVGVVAAIVLWNSVYVVQQTERAVMLRFGRVVESDVKPGLHFKIPYVNQVRKFDARLLT 68

Query: 70  IDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIV-----KLAQTNLRAII 124
           +D P Q  +  +   V VDA   +++ D  +  Y  +  L  I      +  +  LR   
Sbjct: 69  LDAPTQRFLTLEKKAVMVDAYAKWRVAD-AERFYTATSGLKQIADERLSRRLEAGLRDQF 127

Query: 125 GEMELDETLSG-RDIINAKLREELDKITDR-WGVKITRVEIQRIDPPKDIQEAMAKQMTA 182
           G+  L E +SG RD +   +   L+++  +  G+++  V ++ ID PK++  ++ ++M+ 
Sbjct: 128 GKRTLHEVVSGERDALMGDITASLNRMAQKELGIEVIDVRVKAIDLPKEVNRSVFERMST 187

Query: 183 EREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEA 232
           ERE           +EA    A+G++ A  ++A+ ++QR++++AE   E+
Sbjct: 188 ERE-----------REAREHRAKGRELAEGIRADADRQRRVIVAEAYRES 226


>sp|P44546|HFLK_HAEIN HFLK PROTEIN >gi|1075179|pir||A64051 probable integral membrane
           proteinase (EC 3.4.-.-) hflK - Haemophilus influenzae
           (strain Rd KW20) >gi|1573108|gb|AAC21822.1| (U32701)
           hflK protein (hflK) [Haemophilus influenzae Rd]
           Length = 410
           
 Score = 90.5 bits (221), Expect = 2e-17
 Identities = 61/255 (23%), Positives = 135/255 (52%), Gaps = 5/255 (1%)

Query: 6   GGVALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVVDL 65
           G V  + + I  +I  +     I+  ++G+V R G+ + ++ PG+++   F+++V  V++
Sbjct: 85  GKVIPLAVAIGAIIWGVNGFYTIKEAERGVVLRFGELHSIVQPGLNWKPTFVDKVLPVNV 144

Query: 66  REHVIDVPPQ-EVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAII 124
            E V ++  Q  ++ +D  +V V+  V Y++ DP K +++V++   ++ +   + LR +I
Sbjct: 145 -EQVKELRTQGAMLTQDENMVKVEMTVQYRVQDPAKYLFSVTNADDSLNQATDSALRYVI 203

Query: 125 GEMELDETLS-GRDIINAKLREELDKITDRW--GVKITRVEIQRIDPPKDIQEAMAKQMT 181
           G M +++ L+ GR ++     + L++I   +  G+++  V  Q   PP+++++A    + 
Sbjct: 204 GHMSMNDILTTGRSVVRENTWKALNEIIKSYDMGLEVIDVNFQSARPPEEVKDAFDDAIK 263

Query: 182 AEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEALK 241
           A+ +++  I  AE         A G  Q  + +A   K R +L A+G+ E ++++L   K
Sbjct: 264 AQEDEQRFIREAEAYAREKEPIARGDAQRILEEATAYKDRIVLDAKGEVERLQRLLPEFK 323

Query: 242 MADEKYLTLQYIEKL 256
            A +      YI+ +
Sbjct: 324 AAPDLLRERLYIQTM 338


>gb|AAF47921.1| (AE003481) CG7468 gene product [Drosophila melanogaster]
           Length = 382
           
 Score = 90.1 bits (220), Expect = 3e-17
 Identities = 50/126 (39%), Positives = 76/126 (59%), Gaps = 2/126 (1%)

Query: 21  LLLSVKVIRPYQKGLVERLGKFNR--LLDPGIHFIIPFMERVKVVDLREHVIDVPPQEVI 78
           L +  KV++ Y++ ++ RLG+  +     PGI FI+P ++    VDLR    DVPPQEV+
Sbjct: 7   LFVCFKVVQEYERAVIFRLGRLMQGGAKGPGIFFILPCIDSYARVDLRTRTYDVPPQEVL 66

Query: 79  CKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDI 138
            KD+V V+VDAVVYY++ +   ++ NV +   +   LAQT LR  +G   L E LS R  
Sbjct: 67  TKDSVTVSVDAVVYYRVSNATVSIANVENAHHSTRLLAQTTLRNTMGTRHLHEILSERMT 126

Query: 139 INAKLR 144
           I+  ++
Sbjct: 127 ISGTMQ 132


>sp|O51221|HFLK_BORBU HFLK PROTEIN >gi|7463666|pir||C70125 Lambda CII stability-governing
           protein (hflK) homolog - Lyme disease spirochete
           >gi|2688090|gb|AAC66586.1| (AE001130) Lambda CII
           stability-governing protein (hflK) [Borrelia
           burgdorferi]
           Length = 311
           
 Score = 88.5 bits (216), Expect = 8e-17
 Identities = 68/253 (26%), Positives = 127/253 (49%), Gaps = 25/253 (9%)

Query: 10  LIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMER-----VKVV- 63
           +II  I + I+++ ++ ++ P ++ +V RLGK NR LD GIH  IP +E      VK+V 
Sbjct: 17  IIITLILISIIVIANIFIVGPSEEAIVLRLGKLNRTLDSGIHVKIPLIEEKFIVPVKIVQ 76

Query: 64  -----------DLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAI 112
                      D+RE+        +I  D  ++ ++ +V Y+I DP    + V D    I
Sbjct: 77  EIKFGFLISPSDIRENDNANDESRIITGDLNIINIEWLVQYKIRDPYSFKFKVEDPETTI 136

Query: 113 VKLAQTNLRAIIGEMELDETLSGRDI-INAKLREELDKITDRW--GVKITRVEIQRIDPP 169
             +A++++  +IG+  + E ++   + I   ++  +++I D +  G+ + +V+I+   PP
Sbjct: 137 KDIAKSSMNRLIGDNTIFEIINDNRVGITEGVKSSMNEIIDNYNLGIDVVQVQIRNALPP 196

Query: 170 K-DIQEAMAKQMTAEREKRAMILIAEGKKE--AAIREAEGQKQAAILKAEGEKQRQILIA 226
           K  + EA      A ++K     I EG+KE    + + +G+    I +A G K+ +I  A
Sbjct: 197 KGKVYEAFEDVNIAIQDKNK--YINEGRKEFNQIVPKIKGEALKVIEEARGYKESRINNA 254

Query: 227 EGQAEAIRKVLEA 239
               E    +L+A
Sbjct: 255 LADTEIFNAILDA 267


>sp|P25661|HFLC_ECOLI HFLC PROTEIN >gi|280066|pir||C43653 probable integral membrane
           proteinase (EC 3.4.-.-) hflC - Escherichia coli
           >gi|436158|gb|AAC43400.1| (U00005) putative integral
           membrane protease required for high frequency
           lysogenization by bacteriophage lambda [Escherichia
           coli] >gi|537016|gb|AAA97071.1| (U14003) CG Site No.
           17520; alternate gene name hflA; putative integral
           membrane protease required for high frequency
           lysogenization by bacteriophage lambda [Escherichia
           coli] >gi|1790617|gb|AAC77132.1| (AE000489) protease
           specific for phage lambda cII repressor [Escherichia
           coli K12]
           Length = 334
           
 Score = 88.2 bits (215), Expect = 1e-16
 Identities = 71/291 (24%), Positives = 133/291 (45%), Gaps = 52/291 (17%)

Query: 9   ALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNR-------LLDPGIHFIIPFMERVK 61
           ++I + I +L++L +SV V++  ++G+  R GK  R       + +PG+HF IPF+E VK
Sbjct: 4   SVIAIIIIVLVVLYMSVFVVKEGERGITLRFGKVLRDDDNKPLVYEPGLHFKIPFIETVK 63

Query: 62  VVDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVY-----NVSDFLMAIVKLA 116
           ++D R   +D      + K+   + VD+ + ++I D  +        ++S   + + +  
Sbjct: 64  MLDARIQTMDNQADRFVTKEKKDLIVDSYIKWRISDFSRYYLATGGGDISQAEVLLKRKF 123

Query: 117 QTNLRAIIGEMELDE---------TLSGRDIINAKLREELDKITD--------------- 152
              LR+ IG +++ +         TL  RD +N+      D++T                
Sbjct: 124 SDRLRSEIGRLDVKDIVTDSRGRLTLEVRDALNSGSAGTEDEVTTPAADNAIAEAAERVT 183

Query: 153 ----------------RWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGK 196
                             G+++  V I++I+ P ++ EA+  +M AERE  A    ++G+
Sbjct: 184 AETKGKVPVINPNSMAALGIEVVDVRIKQINLPTEVSEAIYNRMRAEREAVARRHRSQGQ 243

Query: 197 KEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEALKMADEKY 247
           +EA    A    +     AE E+Q +I+  EG AEA +   +A     + Y
Sbjct: 244 EEAEKLRATADYEVTRTLAEAERQGRIMRGEGDAEAAKLFADAFSKDPDFY 294


>gi|4759148 stomatin-like protein 1 [Homo sapiens] >gi|4160546|emb|CAA76271.1|
           (Y16522) SLP-1 protein [Homo sapiens]
           Length = 394
           
 Score = 86.6 bits (211), Expect = 3e-16
 Identities = 54/175 (30%), Positives = 93/175 (52%), Gaps = 8/175 (4%)

Query: 13  LGIFLLIMLL-----LSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVVDLRE 67
           LG  LL++        ++K++  Y++ +V RLG+      PG+  ++PF++  + VDLR 
Sbjct: 62  LGFLLLLVTFPISGWFALKIVPTYERMIVFRLGRIRTPQGPGMVLLLPFIDSFQRVDLRT 121

Query: 68  HVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEM 127
              +VPP ++  KD  V++V A V ++I DPV +V  V D   A    AQ  +   + + 
Sbjct: 122 RAFNVPPCKLASKDGAVLSVGADVQFRIWDPVLSVMTVKDLNTATRMTAQNAMTKALLKR 181

Query: 128 ELDETLSGRDIINAKLREELDKITDRWGVKITRVEI---QRIDPPKDIQEAMAKQ 179
            L E    +  I+ +L  E++ +T  WG+++ RVE+     + PP+D Q A   Q
Sbjct: 182 PLREIQMEKLKISDQLLLEINDVTRAWGLEVDRVELAVEAVLQPPQDSQLAQPGQ 236


>pir||T32977 unc-24 protein - Caenorhabditis elegans >gi|1353669|gb|AAB06496.1|
           (U42013) UNC-24 [Caenorhabditis elegans]
           >gi|2854188|gb|AAC02604.1| (AF045644) C. elegans UNC-24
           bipartite protein similar to both erythrocyte band 7.2
           (stomatin) and nonspecific lipid transfer protein
           (GB:U42013) [Caenorhabditis elegans]
           Length = 415
           
 Score = 85.4 bits (208), Expect = 7e-16
 Identities = 53/166 (31%), Positives = 91/166 (53%), Gaps = 2/166 (1%)

Query: 8   VALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVVDLRE 67
           V+ + + + + + LL ++K I   +K +V RLG+  +   PGI  +IP ++    V +  
Sbjct: 71  VSFLFVVMTMPLSLLFALKFISTSEKLVVLRLGRAQKTRGPGITLVIPCIDTTHKVTMSI 130

Query: 68  HVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEM 127
              +VPP ++I  D  +V + A V+ +I DP+ AV  V D   ++  LA T L   I + 
Sbjct: 131 TAFNVPPLQIITTDRGLVELGATVFLKIRDPIAAVCGVQDRNASVRTLANTMLYRYISKK 190

Query: 128 ELDETLSGRD--IINAKLREELDKITDRWGVKITRVEIQRIDPPKD 171
            + +  S +D  II+A L++EL   T ++GV+IT VEI  +   K+
Sbjct: 191 RICDVTSSQDRRIISANLKDELGSFTCQFGVEITDVEISDVKIVKE 236


>sp|P57631|HFLK_BUCAI HFLK PROTEIN >gi|10039224|dbj|BAB13258.1| (AP001119) hflK protein
           [Buchnera sp. APS]
           Length = 406
           
 Score = 85.4 bits (208), Expect = 7e-16
 Identities = 64/255 (25%), Positives = 122/255 (47%), Gaps = 5/255 (1%)

Query: 11  IILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVVDLREHVI 70
           II+ I   I  +     I   ++G+V   GKF+ L+ PG+++   F   VK V++ E V 
Sbjct: 70  IIIFISFFIWGVSGFYTITEAERGVVTSFGKFSHLVQPGLNWRPVFFNEVKPVNV-ETVR 128

Query: 71  DVPPQEV-ICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMEL 129
           ++    + +  D  VV V+  V Y+I +P   +++V     ++ +   + LR +IG   +
Sbjct: 129 ELATSGIMLTADENVVRVEMNVQYKITNPADYLFSVCYPDDSLRQATDSALRGVIGHSTM 188

Query: 130 DETLS-GRDIINAKLREELDKITD--RWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREK 186
           D  L+ GR ++ +  ++E++      + G+ I  V  Q   PP++++ A    + A   +
Sbjct: 189 DRVLTEGRTLVRSDTQKEIENTIKPYKMGITILDVNFQTARPPEEVKAAFDDAIAARENR 248

Query: 187 RAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEALKMADEK 246
              +  AE        +A G+ Q  + +A+    R IL A+G+     K+L   ++A + 
Sbjct: 249 EQYVREAEAYSNEVKPKANGKAQRILEEAKSYSSRIILQAQGEVARFSKILPEYRIAKKI 308

Query: 247 YLTLQYIEKLPDLAK 261
            L   YIE +  L +
Sbjct: 309 TLKRLYIESMERLLR 323


>emb|CAB52016.1| (AL109665) SLP-1 [Homo sapiens]
           Length = 390
           
 Score = 84.3 bits (205), Expect = 2e-15
 Identities = 51/167 (30%), Positives = 90/167 (53%), Gaps = 8/167 (4%)

Query: 13  LGIFLLIMLL-----LSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVVDLRE 67
           LG  LL++        ++K++  Y++ +V RLG+      PG+  ++PF++  + VDLR 
Sbjct: 55  LGFLLLLVTFPISGWFALKIVPTYERMIVFRLGRIRTPQGPGMVLLLPFIDSFQRVDLRT 114

Query: 68  HVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEM 127
              +VPP ++  KD  V++V A V ++I DPV +V  V D   A    AQ  +   + + 
Sbjct: 115 RAFNVPPCKLASKDGAVLSVGADVQFRIWDPVLSVMTVKDLNTATRMTAQNAMTKALLKR 174

Query: 128 ELDETLSGRDIINAKLREELDKITDRWGVKITRVEI---QRIDPPKD 171
            L E    +  I+ +L  E++ +T  WG+++ RVE+     + PP+D
Sbjct: 175 PLREIQMEKLKISDQLLLEINDVTRAWGLEVDRVELAVEAVLQPPQD 221


>gb|AAF06960.1| (AF156557) stomatin related protein [Homo sapiens]
           >gi|6671068|gb|AAF23080.1| (AF156564) stomatin related
           protein [Homo sapiens]
           Length = 398
           
 Score = 84.3 bits (205), Expect = 2e-15
 Identities = 51/167 (30%), Positives = 90/167 (53%), Gaps = 8/167 (4%)

Query: 13  LGIFLLIMLL-----LSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVVDLRE 67
           LG  LL++        ++K++  Y++ +V RLG+      PG+  ++PF++  + VDLR 
Sbjct: 62  LGFLLLLVTFPISGWFALKIVPTYERMIVFRLGRIRTPQGPGMVLLLPFIDSFQRVDLRT 121

Query: 68  HVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEM 127
              +VPP ++  KD  V++V A V ++I DPV +V  V D   A    AQ  +   + + 
Sbjct: 122 RAFNVPPCKLASKDGAVLSVGADVQFRIWDPVLSVMTVKDLNTATRMTAQNAMTKALLKR 181

Query: 128 ELDETLSGRDIINAKLREELDKITDRWGVKITRVEI---QRIDPPKD 171
            L E    +  I+ +L  E++ +T  WG+++ RVE+     + PP+D
Sbjct: 182 PLREIQMEKLKISDQLLLEINDVTRAWGLEVDRVELAVEAVLQPPQD 228


>pir||B82806 integral membrane proteinase XF0453 [imported] - Xylella fastidiosa
           (strain 9a5c) >gi|9105297|gb|AAF83263.1|AE003895_14
           (AE003895) integral membrane proteinase [Xylella
           fastidiosa]
           Length = 287
           
 Score = 84.3 bits (205), Expect = 2e-15
 Identities = 72/233 (30%), Positives = 116/233 (48%), Gaps = 10/233 (4%)

Query: 11  IILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRL-LDPGIHFIIPFMERVKVVDLREHV 69
           I++   L + L  S+ V+R  Q  +V  LG+  R  L  G+HF IP +E V++ D R  V
Sbjct: 7   IVVTAVLFLSLFSSIFVVREDQTAMVINLGRVVRYDLKSGLHFKIPLVESVRLFDRRFKV 66

Query: 70  IDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVS--DFLMAIVKLAQT---NLRAII 124
           +   P      +   V+VD      I D V++ Y  +  D   A  +LA     +LR  I
Sbjct: 67  MATEPARYFTAEQKDVSVDFFAIGYIED-VRSFYRATGGDESQAAARLAPIITDSLRNQI 125

Query: 125 GEMELDETLSG-RDIINAKLREELDKITDRWGVKITRVEIQRIDPPKDIQ--EAMAKQMT 181
               L E +SG R  + A   + ++  T   GV I  + I++I+ P D Q    + ++M 
Sbjct: 126 NSRTLQELVSGDRSELIAGQLKSINAATKGLGVHIVDLRIKQIELPVDSQVISDVYERMR 185

Query: 182 AEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIR 234
           A+R++ A  L AEG++ +    A+  +++ +L A+ E+  Q L  EG AEA R
Sbjct: 186 AQRKQEAAKLRAEGEERSLSIRAQADRESTVLIADAERDAQKLRGEGDAEAAR 238


>gi|11432457 stomatin-like protein 1 [Homo sapiens]
           Length = 267
           
 Score = 84.3 bits (205), Expect = 2e-15
 Identities = 51/167 (30%), Positives = 90/167 (53%), Gaps = 8/167 (4%)

Query: 13  LGIFLLIMLL-----LSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVVDLRE 67
           LG  LL++        ++K++  Y++ +V RLG+      PG+  ++PF++  + VDLR 
Sbjct: 62  LGFLLLLVTFPISGWFALKIVPTYERMIVFRLGRIRTPQGPGMVLLLPFIDSFQRVDLRT 121

Query: 68  HVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEM 127
              +VPP ++  KD  V++V A V ++I DPV +V  V D   A    AQ  +   + + 
Sbjct: 122 RAFNVPPCKLASKDGAVLSVGADVQFRIWDPVLSVMTVKDLNTATRMTAQNAMTKALLKR 181

Query: 128 ELDETLSGRDIINAKLREELDKITDRWGVKITRVEI---QRIDPPKD 171
            L E    +  I+ +L  E++ +T  WG+++ RVE+     + PP+D
Sbjct: 182 PLREIQMEKLKISDQLLLEINDVTRAWGLEVDRVELAVEAVLQPPQD 228


>emb|CAB64583.1| (AL135941) hypothetical protein L391.06 [Leishmania major]
           Length = 277
           
 Score = 83.9 bits (204), Expect = 2e-15
 Identities = 71/236 (30%), Positives = 115/236 (48%), Gaps = 12/236 (5%)

Query: 34  GLVERLGKFNRLLDPGIHFIIPFMERVKVVDLR--EHVIDVPPQEVICKDNVVVTVDAVV 91
           G+VE  G+F+   DPGIH +      V+ V LR  E+ + V   E   KDNV VT+  V+
Sbjct: 13  GIVETCGRFSYTADPGIHCLWCGSVLVRRVTLRLQEYELKV---ESKTKDNVFVTLSLVI 69

Query: 92  YYQIL-DPVKAVYNVSDFLMAIVK-LAQTNLRAIIGEMELDETLSGRDIINAKLREELDK 149
            YQ+  D +  VY   D  +  ++     ++RA I   +L+     R  I+ +L++E+D 
Sbjct: 70  QYQVSPDKLAEVYYACDSSLQCMRDYVLNSIRAKIPLYKLEALYVERGTISQQLKDEVDA 129

Query: 150 ITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQ 209
           I   +G++I    I  IDP  +I +AM +    +R + A +  AE +K   +R AE + +
Sbjct: 130 IIGTYGIEIVSALISDIDPGAEITKAMNEVQKFQRLRVASVDAAETEKLKRVRAAEARCE 189

Query: 210 AAILKAEGEKQRQILIAEGQAEAIRKVLEALK-----MADEKYLTLQYIEKLPDLA 260
           A  L  EG  +++  I  G   +I  V   ++      A    L  QY + L  +A
Sbjct: 190 ARRLSGEGLAEQRKAIVAGLMHSIEDVQSEVRDLTSNDATNMLLMNQYYDTLQAIA 245


>sp|P57630|HFLC_BUCAI HFLC PROTEIN >gi|10039223|dbj|BAB13257.1| (AP001119) hflC protein
           [Buchnera sp. APS]
           Length = 310
           
 Score = 83.5 bits (203), Expect = 3e-15
 Identities = 71/291 (24%), Positives = 140/291 (47%), Gaps = 27/291 (9%)

Query: 10  LIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNR-------LLDPGIHFIIPFMERVKV 62
           LI     L ++L  S  +++  ++G+V + GK  R       + +PG+HF  PF+E VK+
Sbjct: 5   LIFASSVLFLILSSSFFIVKEGERGIVLQFGKVLRNNELKTVVYNPGLHFKWPFLETVKM 64

Query: 63  VDLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVK--AVYNVSDFLMAIVKLAQ--- 117
           +D R H +D      + K+   + VD+ + ++I D  +        D   A V L +   
Sbjct: 65  LDARIHTMDNQADRFVTKEKKDLIVDSYIKWRINDFSRYYLATGGGDVFQAEVLLKRKFS 124

Query: 118 TNLRAIIGEMELDETLS---GR---DIINA--KLREELDKIT-------DRWGVKITRVE 162
             LR+ IG + + E ++   GR   D++N+  K    L+K +       +  G+ +  V 
Sbjct: 125 DRLRSEIGRLNVKEIVTDSRGRLTTDVLNSLNKGSMNLEKSSLINVNSMNALGIHVVDVR 184

Query: 163 IQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQ 222
           I++I+ P ++ +A+  +M AERE  A    ++G+++A    A    + +I+ +E  K+  
Sbjct: 185 IKQINLPVEVSDAIYNRMRAEREAVARSQRSQGQEKAEKLRASADYKVSIILSEARKEAL 244

Query: 223 ILIAEGQAEAIRKVLEALKMADEKYLTLQYIEKLPDLAKYGNLIVPYDTES 273
           I+  +G+AE  +   +      + Y  ++ +    +  K    I+  D++S
Sbjct: 245 IIKGQGEAEVTKLFAKNFNKEPDFYFFIRSLRAYENSFKNNRNIMLIDSDS 295


>sp|O83151|HFLK_TREPA HFLK PROTEIN >gi|7521161|pir||H71364 probable Lambda CII
           stability-governing protein (hflK) - syphilis spirochete
           >gi|3322375|gb|AAC65102.1| (AE001196) Lambda CII
           stability-governing protein (hflK) [Treponema pallidum]
           Length = 328
           
 Score = 83.1 bits (202), Expect = 4e-15
 Identities = 74/302 (24%), Positives = 142/302 (46%), Gaps = 27/302 (8%)

Query: 12  ILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVVDL------ 65
           +LGI +++ +   +++I P   G+V R GK++R L+PG+H++IPF+E V  V +      
Sbjct: 21  VLGI-VIVGIASPIRIISPTDNGVVTRFGKYHRTLEPGLHYLIPFVEWVYKVPVTKVQKE 79

Query: 66  -----------REHVIDVPPQE--VICKDNVVVTVDAVVYYQILDPVKAVYNV--SDFLM 110
                      + H ++    E  ++  D  +V V+ VV Y+I+DP   V+NV   +   
Sbjct: 80  EFGFRTSKSSEQSHYVNNISHESLMLTGDLNIVDVEWVVQYRIVDPRAWVFNVESQERRQ 139

Query: 111 AIVKLAQTNLRAIIGEME-LDETLSGRDIINAKLREELDKITDR--WGVKITRVEIQRID 167
            I  +++  + ++IG+   LD     R  I  + ++ ++ +  R   GV ++ V++Q + 
Sbjct: 140 TIRDISKAVVNSLIGDRAILDIMGPERSAIQMRAKDMMNVLLKRIGLGVLVSSVQLQNVV 199

Query: 168 PPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAE 227
           PP+++Q+A      A ++   +I   +      I +A G     I +A G    ++  A+
Sbjct: 200 PPQEVQQAFEDVNIAIQDMNRLINEGKESYNREIPKARGDADKLIQEAMGYANERVNRAK 259

Query: 228 GQAEAIRKVLEALKMADEKYLTLQYIEKL-PDLAKYGN-LIVPYDTESLIGLLRVLQKVK 285
           G       +      A     T  Y+E L   L K  N L++    E+L+ L  + +  K
Sbjct: 260 GDVARFDSIYAEYVKAPHVTKTRLYLEGLGAILEKTENVLLIDKKLENLLTLKDISKVSK 319

Query: 286 SI 287
            +
Sbjct: 320 KV 321


>gb|AAF03497.1|AC010676_7 (AC010676) unknown protein [Arabidopsis thaliana]
           >gi|6714460|gb|AAF26146.1|AC008261_3 (AC008261) unknown
           protein [Arabidopsis thaliana]
           Length = 285
           
 Score = 80.4 bits (195), Expect = 2e-14
 Identities = 61/202 (30%), Positives = 104/202 (51%), Gaps = 7/202 (3%)

Query: 37  ERLGKFNRLLDPGIHFIIPFMERVKV---VDLREHVIDVPPQEVICKDNVVVTVDAVVYY 93
           ER GKF ++L+PG+ F+ P++    V   + LR   +DV   E   KDNV VTV A + Y
Sbjct: 19  ERFGKFQKVLNPGLQFV-PWVIGDYVAGTLTLRLQQLDVQC-ETKTKDNVFVTVVASIQY 76

Query: 94  QIL--DPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKLREELDKIT 151
           ++L      A Y +S+    I       +RA + ++ LD+    ++ I   + EELDK  
Sbjct: 77  RVLADKASDAFYRLSNPTTQIKAYVFDVIRACVPKLNLDDVFEQKNEIAKSVEEELDKAM 136

Query: 152 DRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQAA 211
             +G +I +  I  I+P + ++ AM +   A R + A    AE +K   I+ AEG+ ++ 
Sbjct: 137 TAYGYEILQTLIIDIEPDQQVKRAMNEINAAARMRVAASEKAEAEKIIQIKRAEGEAESK 196

Query: 212 ILKAEGEKQRQILIAEGQAEAI 233
            L   G  +++  I +G  +++
Sbjct: 197 YLSGLGIARQRQAIVDGLRDSV 218


>gb|AAF07389.1|AC010675_12 (AC010675) unknown protein; 58197-59415 [Arabidopsis thaliana]
           Length = 286
           
 Score = 80.0 bits (194), Expect = 3e-14
 Identities = 67/246 (27%), Positives = 117/246 (47%), Gaps = 15/246 (6%)

Query: 37  ERLGKFNRLLDPGIHFIIPFMERVKV---VDLREHVIDVPPQEVICKDNVVVTVDAVVYY 93
           E  GKF+ +L+PG H  +P+    +V   + LR   +DV   E   KDNV VTV A + Y
Sbjct: 19  ETFGKFDEVLEPGCH-CLPWCLGSQVAGHLSLRVQQLDVRC-ETKTKDNVFVTVVASIQY 76

Query: 94  QIL--DPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKLREELDKIT 151
           + L      A Y +S+    I       +RA + +++LD T   ++ I   +  EL+K  
Sbjct: 77  RALAESAQDAFYKLSNTRNQIQAYVFDVIRASVPKLDLDSTFEQKNDIAKTVETELEKAM 136

Query: 152 DRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQAA 211
             +G +I +  I  I+P   ++ AM +   A R + A    AE +K   I+ AEG+ ++ 
Sbjct: 137 SHYGYEIVQTLIVDIEPDVHVKRAMNEINAASRMREAASEKAEAEKILQIKRAEGEAESK 196

Query: 212 ILKAEGEKQRQILIAEGQAEAIRKVLEALKMADEK-----YLTLQYIEKLPDL---AKYG 263
            L   G  +++  I +G   ++    E++     K      L  QY + L ++   +K  
Sbjct: 197 YLSGMGIARQRQAIVDGLRNSVLAFSESVPGTSSKDVMDMVLVTQYFDTLKEIGASSKSN 256

Query: 264 NLIVPY 269
           ++ +P+
Sbjct: 257 SVFIPH 262


>dbj|BAB06874.1| (AP001517) protease specific for phage lambda cII repressor
           [Bacillus halodurans]
           Length = 319
           
 Score = 79.6 bits (193), Expect = 4e-14
 Identities = 75/313 (23%), Positives = 146/313 (45%), Gaps = 31/313 (9%)

Query: 8   VALIILGIFLLIMLLLSVKVIRPYQKGLVERLGKFNRLLD-PGIHFIIPF-MERVKVV-- 63
           +   ILG+FL+        ++   ++  +   GK    +D PG+ F +P+ +++V+++  
Sbjct: 14  IGAAILGLFLVT----GWYIVDETEQAALITFGKVEETIDEPGLKFKMPWPIQKVEILPR 69

Query: 64  -----------DLREHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAI 112
                      D  E V      ++I  D  +V  D  V ++I DP + +Y+  D    +
Sbjct: 70  GTFNLQVGYKEDEGEVVEFTDEAKMITGDENIVFADLAVQWRITDPEQYLYSTEDPKELL 129

Query: 113 VKLAQTNLRAIIGEMELDETLSG-RDIINAKLREELDKITDRW--GVKITRVEIQRID-P 168
                + LR++IG   +DE L+  R  I A + E L ++ D +  G+ I+ V++Q ++ P
Sbjct: 130 YNATSSALRSVIGSASVDEALTDERPTIEADIFESLVELMDLYQIGISISDVKLQDVELP 189

Query: 169 PKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEG 228
            ++++ A      A  E+   I  A   +     E EG+K A I +AEG++  +I  A G
Sbjct: 190 TEEVRRAFTDVTDAREERLTKINEANRYRNQETNEVEGEKDAIISRAEGQRADRIETARG 249

Query: 229 QAEAIRKVLEALKM---ADEKYLTLQYIEK-LPDLAKYGNLIVPYDTESLIGL-LRVLQK 283
                  + E   +      + L L+ +E  LPD   Y   I+  + +++  L +R L++
Sbjct: 250 DVARFNALYEEYLVNPDVTRQRLVLETLESILPDTEIY---IMDSNNDTINYLPIRPLER 306

Query: 284 VKSIPLQQSTEKK 296
            +  P+++ T  +
Sbjct: 307 QQQAPVEEGTNNE 319


>gb|AAF68390.1|AF236374_1 (AF236374) hypersensitive-induced response protein [Zea mays]
           Length = 284
           
 Score = 78.8 bits (191), Expect = 7e-14
 Identities = 67/246 (27%), Positives = 119/246 (48%), Gaps = 15/246 (6%)

Query: 37  ERLGKFNRLLDPGIHFIIPFMERVKV---VDLREHVIDVPPQEVICKDNVVVTVDAVVYY 93
           E  GKF+ +L+PG HF+ P+    ++   + LR   +DV   E   KDNV VTV A V Y
Sbjct: 19  ENFGKFSEVLEPGCHFL-PWCIGQQIAGYLSLRVRQLDVRC-ETKTKDNVFVTVVASVQY 76

Query: 94  QIL--DPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKLREELDKIT 151
           + L      A Y +S+    I       +RA + ++ LD+    ++ I   + EEL+K  
Sbjct: 77  RALADKASDAFYKLSNTREQIQSYVFDVIRATVPKLGLDDAFEQKNEIAKAVEEELEKAM 136

Query: 152 DRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQAA 211
             +G +I +  I  I+P   ++ AM +   A R + A    AE +K   I++AEG+ ++ 
Sbjct: 137 STYGYQIVQTLIVDIEPDDRVKRAMNEINAAARMRVAASEKAEAEKILQIKKAEGEAESK 196

Query: 212 ILKAEGEKQRQILIAEGQAEAIRKVLE-----ALKMADEKYLTLQYIEKLPDL---AKYG 263
            L   G  +++  I +G  +++    E       K   +  L  QY + + ++   +K  
Sbjct: 197 YLAGVGIARQRQAIVDGLRDSVLAFSENVPGTTAKDIMDMVLVTQYFDTMREIGASSKSS 256

Query: 264 NLIVPY 269
           ++ +P+
Sbjct: 257 SVFIPH 262


>gb|AAF68391.1|AF236375_1 (AF236375) hypersensitive-induced response protein [Zea mays]
           Length = 287
           
 Score = 77.6 bits (188), Expect = 2e-13
 Identities = 60/202 (29%), Positives = 101/202 (49%), Gaps = 7/202 (3%)

Query: 37  ERLGKFNRLLDPGIHFIIPFMERVKV---VDLREHVIDVPPQEVICKDNVVVTVDAVVYY 93
           E+ GKF+ +L+PG H  +P+    +V   + LR   +DV   E   KDNV V V A + Y
Sbjct: 19  EQFGKFDSVLEPGCH-CMPWFAGKRVAGQLTLRLQQLDVRC-ETKTKDNVFVNVVASIQY 76

Query: 94  QIL--DPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKLREELDKIT 151
           + L      A Y +S+    I       +RA + ++ LD+    +D I   + EEL+K  
Sbjct: 77  RALADKASDAFYKLSNTRSQIQAYVFDVIRASVPKLHLDDAFEQKDEIARAVEEELEKAM 136

Query: 152 DRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQAA 211
             +G +I +  I  I+P + ++ AM +   A R + A    AE +K   I+ AEG+ +A 
Sbjct: 137 SAYGFEIVQTLIVDIEPDEHVKRAMNEINAAARLRAAANEKAEAEKIVQIKRAEGEAEAK 196

Query: 212 ILKAEGEKQRQILIAEGQAEAI 233
            L   G  +++  I +G  +++
Sbjct: 197 YLSGLGIARQRQAIVDGLRDSV 218


>gb|AAF68389.1|AF236373_1 (AF236373) hypersensitive-induced response protein [Zea mays]
           Length = 284
           
 Score = 76.9 bits (186), Expect = 3e-13
 Identities = 66/246 (26%), Positives = 117/246 (46%), Gaps = 15/246 (6%)

Query: 37  ERLGKFNRLLDPGIHFIIPFMERVKV---VDLREHVIDVPPQEVICKDNVVVTVDAVVYY 93
           E  GKF+ +L+PG HF+ P+    ++   + LR   +DV   E   KDNV V V A V Y
Sbjct: 19  ETFGKFDEVLEPGCHFL-PWCIGKQIAGYLSLRVQQLDVRC-ETKTKDNVFVNVVASVQY 76

Query: 94  QIL--DPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKLREELDKIT 151
           + L      A Y +S+    I       +RA + +M LD+    ++ I   +  EL+K  
Sbjct: 77  RALADKASDAFYRLSNTREQIQSYVFDVIRASVPKMNLDDAFEQKNEIAKAVENELEKAM 136

Query: 152 DRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQAA 211
             +G +I +  I  I+P + ++ AM +   A R + A    AE +K   I+ AEG  ++ 
Sbjct: 137 SMYGYEIVQTLIVDIEPDEHVKRAMNEINAAARLRLAASEKAEAEKILQIKRAEGDAESK 196

Query: 212 ILKAEGEKQRQILIAEGQAEAIRKVLE-----ALKMADEKYLTLQYIEKLPDL---AKYG 263
            L   G  +++  I +G  +++    E     + K   +  L  QY + + ++   +K  
Sbjct: 197 YLAGLGIARQRQAIVDGLRDSVLAFSENVPGTSAKDVMDMVLVTQYFDTMKEIGASSKSS 256

Query: 264 NLIVPY 269
           ++ +P+
Sbjct: 257 SVFIPH 262


>pir||I39620 hypothetical protein X - Anabaena variabilis (fragment)
           >gi|600250|dbj|BAA04562.1| (D17710) orfX [Anabaena
           variabilis]
           Length = 293
           
 Score = 76.5 bits (185), Expect = 4e-13
 Identities = 53/211 (25%), Positives = 105/211 (49%), Gaps = 3/211 (1%)

Query: 28  IRPYQKGLVERLGKFNRLLDPGIH--FIIPFMERVKVVDLREHVIDVPPQEVICKDNVVV 85
           + P   GL+    +F   L  G H  ++     + +V DLR+  ++V  Q+++ KD V +
Sbjct: 65  VPPQHIGLLYINQEFQAQLPSGKHAWWLFGRSWQTEVFDLRQQTLEVSGQDILSKDKVPL 124

Query: 86  TVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKLRE 145
            ++    Y++LDP++A   +SD L  + K  Q  LR  +GE  LD  L  +  I+  + E
Sbjct: 125 RLNLTAGYRLLDPLRARNGLSDILNYLYKELQFALRGAVGERSLDALLEDKGTIDRSIFE 184

Query: 146 ELDKITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAE 205
            + + T  +G+++  V ++ I  P +I+  ++K + AE+  +A + +   ++ AA R   
Sbjct: 185 YIRQKTADYGIEVDSVGVKDIILPGEIKTILSKVVEAEKAAQANV-VRRREETAATRSML 243

Query: 206 GQKQAAILKAEGEKQRQILIAEGQAEAIRKV 236
              +         + +++ + E  AE I K+
Sbjct: 244 NTARVMEDNPVALRLKELEVLERIAEKIEKI 274


>pir||E83340 hypothetical protein PA2438 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9948485|gb|AAG05826.1|AE004671_2
           (AE004671) hypothetical protein [Pseudomonas aeruginosa]
           Length = 341
           
 Score = 75.7 bits (183), Expect = 6e-13
 Identities = 72/269 (26%), Positives = 128/269 (46%), Gaps = 26/269 (9%)

Query: 10  LIILGIFLLIMLLLSVKV-IRPYQKGLVERLGKFNR-LLDPGIHFIIPF-MERVKVVDLR 66
           L++  + +L  +  +  V +R  +  ++ R G   R LL+PG+ + +P   E    VDLR
Sbjct: 37  LLVAALLVLFAVAAACLVQVRSGEAMVITRFGNPARVLLEPGLAWRLPLPFESAIPVDLR 96

Query: 67  EHVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKL---AQTNLRAI 123
                   Q+V  +D + + V A V +Q+        NV  F+ A+      A   LR  
Sbjct: 97  LRTTSSGLQDVGTRDGLRIIVQAYVAWQVQGDAD---NVQRFMRAVRNQPDEAARQLRTF 153

Query: 124 IGEMELDETLSGRDIIN---------------AKLREELD-KITDRWGVKITRVEIQRID 167
           +G   L+ T S  D+ +               A+LRE++D ++   +GVK+ +V I+R+ 
Sbjct: 154 VGSA-LETTASAYDLADLVNTEASRVRIGDFEARLREQIDHQLLATYGVKVVQVGIERLT 212

Query: 168 PPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAE 227
            PK    A   +M AERE  A    AEG+++AA   +  ++ A +++AE   +   + A+
Sbjct: 213 LPKVTLGATVDRMRAERETIATERTAEGRRQAAEIRSAAERDARVIQAEASVKAAEIEAQ 272

Query: 228 GQAEAIRKVLEALKMADEKYLTLQYIEKL 256
            + EA R   +A   + + Y  L+ ++ L
Sbjct: 273 ARVEAARIYGKAYAGSPQLYNLLRSLDTL 301


>emb|CAC07434.1| (AJ292360) putative membrane protein [Zea mays]
           Length = 284
           
 Score = 75.3 bits (182), Expect = 8e-13
 Identities = 64/233 (27%), Positives = 110/233 (46%), Gaps = 12/233 (5%)

Query: 37  ERLGKFNRLLDPGIHFIIPFMERVKV---VDLREHVIDVPPQEVICKDNVVVTVDAVVYY 93
           E  GKF+ +L+PG HF+ P+    ++   + LR   +DV   E   KDNV V V A V Y
Sbjct: 19  ETFGKFDEVLEPGCHFL-PWCIGKQIAGYLSLRVQQLDVRC-ETKTKDNVFVNVVASVQY 76

Query: 94  QIL--DPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKLREELDKIT 151
           + L      A Y +S+    I       +RA + +M LD+    ++ I   +  EL+K  
Sbjct: 77  RALADKASDAFYRLSNTREQIQSYVFDVIRASVPKMNLDDAFEQKNEIAKAVENELEKAM 136

Query: 152 DRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQAA 211
             +G +I +  I  I+P + ++ AM +   A R + A    AE +K   I+ AEG  ++ 
Sbjct: 137 SMYGYEIVQTLIVDIEPDEHVKRAMNEINAAARLRLAASEKAEAEKILQIKRAEGDAESK 196

Query: 212 ILKAEGEKQRQILIAEGQAEAIRKVLE-----ALKMADEKYLTLQYIEKLPDL 259
            L   G  +++  I +G  +++    E     + K   +  L  QY + + ++
Sbjct: 197 YLAGLGIARQRQAIVDGLRDSVLAFSENVPGTSAKDVMDMVLVTQYFDTMEEI 249


>dbj|BAB08673.1| (AB018109) gb|AAF03497.1~gene_id:K17N15.12~similar to unknown
           protein [Arabidopsis thaliana]
           Length = 292
           
 Score = 73.4 bits (177), Expect = 3e-12
 Identities = 59/235 (25%), Positives = 106/235 (45%), Gaps = 10/235 (4%)

Query: 34  GLVERLGKFNRLLDPGIHFIIPFMER--VKVVDLREHVIDVPPQEVICKDNVVVTVDAVV 91
           G+VER G+F  + +PG HF  P   +    V+  R   +DV   E   KDNV V +   +
Sbjct: 18  GVVERWGRFEHIAEPGCHFFNPLAGQWLAGVLSTRIKSLDVKI-ETKTKDNVFVQLVCSI 76

Query: 92  YYQILDPVK--AVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKLREELDK 149
            Y+++      A Y + +    I       +RA++  M LD     +  +   + EEL+K
Sbjct: 77  QYRVVKASADDAFYELQNPKEQIQAYVFDVVRALVPMMTLDALFEQKGEVAKSVLEELEK 136

Query: 150 ITDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQ 209
           +   +G  I  + +  I P   +++AM +   A+R + A +   E +K   ++ AE + +
Sbjct: 137 VMGAYGYSIEHILMVDIIPDPSVRKAMNEINAAQRLQLASVYKGEAEKILQVKRAEAEAE 196

Query: 210 AAILKAEGEKQRQILIAEGQAEAIRKVLEALKMADEK-----YLTLQYIEKLPDL 259
           A  L   G  +++  I +G  E I    + ++    K      +  QY + + DL
Sbjct: 197 AKYLGGVGVARQRQAITDGLRENILNFSDKVEGTSAKEVMDLIMITQYFDTIRDL 251


>pir||C81445 probable transmembrane protein Cj0268c [imported] - Campylobacter
           jejuni (strain NCTC 11168) >gi|6967745|emb|CAB72736.1|
           (AL139074) putative transmembrane protein [Campylobacter
           jejuni]
           Length = 362
           
 Score = 73.0 bits (176), Expect = 4e-12
 Identities = 62/283 (21%), Positives = 138/283 (47%), Gaps = 38/283 (13%)

Query: 6   GGVALIILGIFLLIMLLLSVK---VIRPYQKGLVERLGKFN-RLLDPGIHFIIPFMERVK 61
           G  +  + G+ ++I+ L+  K   VI   + G+    GK++   L+PG+HF +PF++++ 
Sbjct: 40  GKFSPFVYGVIIIILFLIVAKPFMVINSGEMGIKSTTGKYDPNPLEPGLHFFLPFVQKIT 99

Query: 62  VVDLREHVIDVPPQE-----------VICKDNV--------VVTVDAVVYYQILDPVKAV 102
           ++D R   I+    E           VI K+++         V++D  V Y+ L+P++  
Sbjct: 100 IIDTRVRQINYASIEGSNENLSSGSGVINKNSISVLDSRGLPVSIDVTVQYR-LNPLQVP 158

Query: 103 YNVSDFLM-----AIVKLAQTNLRAIIGEMELDETLSGRDIINAKLREELDKITD---RW 154
             ++ + +      I  + +  +R+++G+   +E  + R+ I  ++ E + K  +     
Sbjct: 159 QTIATWSLNWENKIIDPVVRDVVRSVVGKYTAEELPTNRNTIATQIEEGIRKTIEAQPNE 218

Query: 155 GVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIRE---AEGQKQAA 211
            V++  V+++ I  P  ++E + +   A++E        E   + A+++   AEG+  A 
Sbjct: 219 PVELRAVQLREIILPSKVKEQIERVQIAKQEAERTKYEVERANQEALKKAALAEGEANAT 278

Query: 212 ILKAEGEKQRQILIAEGQAEAIRKVLEALKMADEKYLTLQYIE 254
           I+ A+G+     + A+ QA + +++  +L   +   L L+ IE
Sbjct: 279 IISAKGKAMAVKIEADAQAYSNKEIANSL---NTPLLNLKQIE 318


>dbj|BAB10843.1| (AB009053) hypersensitive-induced response protein [Arabidopsis
           thaliana]
           Length = 286
           
 Score = 72.6 bits (175), Expect = 5e-12
 Identities = 59/202 (29%), Positives = 100/202 (49%), Gaps = 7/202 (3%)

Query: 37  ERLGKFNRLLDPGIHFIIPFMERVKV---VDLREHVIDVPPQEVICKDNVVVTVDAVVYY 93
           E  GKF  +L+PG HF+ P+    +V   + LR   +DV   E   KDNV V V A + Y
Sbjct: 19  ETFGKFEDVLEPGCHFL-PWCLGSQVAGYLSLRVQQLDVRC-ETKTKDNVFVNVVASIQY 76

Query: 94  QIL--DPVKAVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKLREELDKIT 151
           + L      A Y +S+    I       +RA + ++ LD+    ++ I   + EEL+K  
Sbjct: 77  RALANKANDAYYKLSNTRGQIQAYVFDVIRASVPKLLLDDVFEQKNDIAKAVEEELEKAM 136

Query: 152 DRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQAA 211
             +G +I +  I  I+P + ++ AM +   A R + A    AE +K   I+ AEG+ ++ 
Sbjct: 137 SAYGYEIVQTLIVDIEPDEHVKRAMNEINAAARMRLAANEKAEAEKILQIKRAEGEAESK 196

Query: 212 ILKAEGEKQRQILIAEGQAEAI 233
            L   G  +++  I +G  +++
Sbjct: 197 YLSGLGIARQRQAIVDGLRDSV 218


>emb|CAB64584.1| (AL135941) hypothetical protein L391.07 [Leishmania major]
           Length = 283
           
 Score = 72.2 bits (174), Expect = 7e-12
 Identities = 56/218 (25%), Positives = 102/218 (46%), Gaps = 15/218 (6%)

Query: 34  GLVERLGKFNRLLDPGIHFIIPFMERVKVVDLREHVIDVPPQEVICKDNVVVTVDAVVYY 93
           G++E  GKF+R  DPG   I+P +E V+ V   +  I     E   +DN VV ++  ++Y
Sbjct: 15  GIIENCGKFDRTADPGCFCIVPCVESVRGVVSLKVAISTVRVETKTRDNAVVNIETRLHY 74

Query: 94  QILDPVK--AVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKLREELDKIT 151
           +++      A Y  S+    I   A + +R  + +  LDE     D I   +  EL +  
Sbjct: 75  KVIAECAEDAFYRFSNPSEQIASFAASVVRGEVPKYTLDELFLMSDEIKKVVSAELTEKL 134

Query: 152 DRWGVKITRVEIQRIDPPKDIQEAMAK-QMTAEREKRAMILIAEGKKEAAIREAEGQKQA 210
             +G  +    + RI+P   ++ A+++ Q+ A R            + AA  E+E  K  
Sbjct: 135 RGFGFSLESTLLTRIEPSASVKTAISQTQINAYR------------RTAAEHESELNKIL 182

Query: 211 AILKAEGEKQRQILIAEGQAEAIRKVLEALKMADEKYL 248
           A+  AE + + + L   G A+  + +++ LK + E ++
Sbjct: 183 AVKAAEADYEEKRLSGVGLAQERQAIMKGLKSSIESFV 220


>sp|P44545|HFLC_HAEIN HFLC PROTEIN >gi|1074959|pir||I64050 probable integral membrane
           proteinase hflC homolog - Haemophilus influenzae (strain
           Rd KW20) >gi|1573107|gb|AAC21821.1| (U32701) hflC
           protein (hflC) [Haemophilus influenzae Rd]
           Length = 295
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 56/235 (23%), Positives = 112/235 (46%), Gaps = 22/235 (9%)

Query: 24  SVKVIRPYQKGLVERLGKFNR-------LLDPGIHFIIPFMERVKVVDLREHVIDVPPQE 76
           S+ V+    +G++ R  K  R       + +PG+HF +P ++ +KV+D R   +D     
Sbjct: 19  SIVVVTEGTRGIMLRFNKVQRDADNKVVVYEPGLHFKVPLIDSIKVLDARIRTLDGSATR 78

Query: 77  VICKDNVVVTVDAVVYYQILDPVKAVYNVS--DFLMAIVKLAQT---NLRAIIGEMELDE 131
            +  +   + VD+ V ++I D  +   +    D+  A   L++     LR+ IG   + +
Sbjct: 79  FVTVEKKDLLVDSYVKWKISDFGRFYTSTGGGDYAQAANLLSRKVNDRLRSEIGSRTIKD 138

Query: 132 TLSGRDIINAKLREELDKI-------TDRWGVKITRVEIQRIDPPKDIQEAMAKQMTAER 184
            +SG      +L E   K        T   G+++  V +++I+ P ++  ++ ++M AER
Sbjct: 139 IVSGT---RGELMEGAKKALSSGQDSTAELGIEVIDVRVKQINLPDEVSSSIYQRMRAER 195

Query: 185 EKRAMILIAEGKKEAAIREAEGQKQAAILKAEGEKQRQILIAEGQAEAIRKVLEA 239
           +  A    ++GK++AA  +A+  ++  ++ A   K  Q L   G A A +   +A
Sbjct: 196 DAVAREHRSQGKEKAAFIQADVDRKVTLILANANKTAQELRGSGDAAAAKLYSDA 250


>emb|CAA10289.1| (AJ131049) hypothetical protein [Cicer arietinum]
           Length = 286
           
 Score = 70.6 bits (170), Expect = 2e-11
 Identities = 62/246 (25%), Positives = 120/246 (48%), Gaps = 15/246 (6%)

Query: 37  ERLGKFNRLLDPGIHFIIPFMERVKV---VDLREHVIDVPPQEVICKDNVVVTVDAVVYY 93
           E+ G+F  +L+PG H  +P+    ++   + LR   +DV   E   KDNV V V A V Y
Sbjct: 19  EQFGRFVDVLEPGCH-CLPWCLGYQIAGGLSLRVQQLDVKC-ETKTKDNVFVMVVASVQY 76

Query: 94  Q-ILDPVK-AVYNVSDFLMAIVKLAQTNLRAIIGEMELDETLSGRDIINAKLREELDKIT 151
           + + D    A Y +++    I       +RA + ++ELD     ++ I   + +EL+K  
Sbjct: 77  RAVADKASDAFYRLTNTREQIQSYVFDVIRASVPKLELDAVFEQKNDIAKAVEDELEKAM 136

Query: 152 DRWGVKITRVEIQRIDPPKDIQEAMAKQMTAEREKRAMILIAEGKKEAAIREAEGQKQAA 211
             +G +I +  I  ++P  +++ AM +   A R + A    AE +K   I++AEG+ ++ 
Sbjct: 137 SNYGYEIVQTLIVDVEPDVNVKRAMNEINAAARLRLAANDKAEAEKILQIKKAEGEAESK 196

Query: 212 ILKAEGEKQRQILIAEGQAEAIRKVLE-----ALKMADEKYLTLQYIEKLPDL---AKYG 263
            L   G  +++  I +G  +++    E     + K   +  L  QY + + ++   +K  
Sbjct: 197 YLSGLGIARQRQAIVDGLRDSVLAFSENVPGTSAKDVMDMVLVTQYFDTMKEIGASSKSS 256

Query: 264 NLIVPY 269
           ++ +P+
Sbjct: 257 SVFIPH 262


>gb|AAD42031.1|AF074953_1 (AF074953) stomatin-like protein UNC24 [Homo sapiens]
           Length = 393
           
 Score = 69.1 bits (166), Expect = 6e-11
 Identities = 51/169 (30%), Positives = 88/169 (51%), Gaps = 11/169 (6%)

Query: 13  LGIFLLIMLL-----LSVKVIRPYQKGLVERLGKFNRLLDPGIHFIIPFMERVKVVDLRE 67
           LG  LL++        ++K++  Y++ +V RLG+      PG+  ++PF++  + VDLR 
Sbjct: 57  LGFLLLLVTFPISGWFALKIVPTYERMIVFRLGRIRTPQGPGMVLLLPFIDSFQRVDLRT 116

Query: 68  HVIDVPPQEVICKDNVVVTVDAVVYYQILDPVKAVYNVSDFLMAIVKLAQTNLRAIIGEM 127
              +VPP ++  KD  V++V A V ++I DPV +V  V D   A    AQ  +   + + 
Sbjct: 117 RAFNVPPCKLASKDGAVLSVGADVQFRIWDPVLSVMTVKDLNTATRMTAQNAMTKALLKR 176

Query: 128 ELDETLSGRDIINAKLREELDKITDR--WGVKITRVEI---QRIDPPKD 171
            L E    +  I+ +L  E D+  D+   G ++ RVE+     + PP+D
Sbjct: 177 PLREIQMEKLKISDQLLLE-DQRCDQGLGGWEVDRVELAVEAVLQPPQD 224


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.321    0.139    0.374 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94872827
Number of Sequences: 2977
Number of extensions: 3672658
Number of successful extensions: 16160
Number of sequences better than 1.0e-10: 112
Number of HSP's better than  0.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 15761
Number of HSP's gapped (non-prelim): 133
length of query: 299
length of database: 189,106,746
effective HSP length: 59
effective length of query: 240
effective length of database: 153,796,013
effective search space: 36911043120
effective search space used: 36911043120
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 165 (68.7 bits)