BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1331 (cheB) DE:protein-glutamate methylesterase (cheB)
         (368 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||E75002 protein-glutamate methylesterase (cheb) PAB1331 - Py...   721  0.0
sp|O58192|CHEB_PYRHO PROTEIN-GLUTAMATE METHYLESTERASE >gi|743507...   701  0.0
sp|Q9WYN9|CHEB_THEMA PROTEIN-GLUTAMATE METHYLESTERASE >gi|743506...   353  2e-96
pir||F83623 probable methylesterase PA0173 [imported] - Pseudomo...   302  4e-81
gi|11498646 protein-glutamate methylesterase (cheB) [Archaeoglob...   291  9e-78
dbj|BAB06154.1| (AP001515) MCP-glutamate methylesterase / two-co...   288  6e-77
sp|P07330|CHEB_ECOLI PROTEIN-GLUTAMATE METHYLESTERASE >gi|67229|...   279  4e-74
gb|AAA23569.1| (M13463) cheB peptide [Escherichia coli]               277  1e-73
sp|P04042|CHEB_SALTY PROTEIN-GLUTAMATE METHYLESTERASE >gi|67228|...   277  2e-73
dbj|BAB15840.1| (AB040876) CheB [Enterobacter cloacae]                272  5e-72
sp|Q05522|CHEB_BACSU PROTEIN-GLUTAMATE METHYLESTERASE >gi|107589...   267  1e-70
sp|O87717|CHEB_CAUCR PROTEIN-GLUTAMATE METHYLESTERASE >gi|338736...   265  8e-70
sp|Q52883|CHEB_RHIME PROTEIN-GLUTAMATE METHYLESTERASE >gi|212079...   262  4e-69
sp|O85128|CHEB_AGRTU PROTEIN-GLUTAMATE METHYLESTERASE >gi|328279...   257  2e-67
gb|AAG19394.1| (AE005033) chemotaxis protein; CheB [Halobacteriu...   255  7e-67
sp|Q48300|CHEB_HALSA PROTEIN-GLUTAMATE METHYLESTERASE >gi|136346...   255  7e-67
pir||H82122 protein-glutamate methylesterase CheB VC2062 [import...   244  1e-63
gb|AAF32418.1| (AF069392) chemotaxis protein CheB [Vibrio paraha...   243  3e-63
sp|O52262|CHEB_PSEPU PROTEIN-GLUTAMATE METHYLESTERASE >gi|285360...   242  7e-63
sp|O87125|CHEB_PSEAE PROTEIN-GLUTAMATE METHYLESTERASE >gi|112626...   241  1e-62
pir||G83463 probable methyltransferase PA1459 [imported] - Pseud...   239  3e-62
gb|AAF67048.1|AF183382_8 (AF183382) methylesterase CheB [Pseudom...   238  8e-62
sp|O83639|CHEB_TREPA PROTEIN-GLUTAMATE METHYLESTERASE >gi|743506...   235  5e-61
sp|P72253|CHEB_RHOCE PROTEIN-GLUTAMATE METHYLESTERASE >gi|162128...   216  3e-55
sp|O33558|CHEB_RHOSH PROTEIN-GLUTAMATE METHYLESTERASE >gi|112626...   215  8e-55
pir||A82206 protein-glutamate methylesterase CheB VC1401 [import...   200  2e-50
sp|O51376|Y415_BORBU PROBABLE PROTEIN-GLUTAMATE METHYLESTERASE B...   178  7e-44
sp|P31758|FRZG_MYXXA PROTEIN-GLUTAMATE METHYLESTERASE FRZG >gi|9...   169  3e-41
pir||F83183 probable methylesterase PA3703 [imported] - Pseudomo...   166  5e-40
sp|Q45047|CHEB_BORBU PROTEIN-GLUTAMATE METHYLESTERASE >gi|743506...   164  2e-39
pdb|1CHD|   Cheb Methylesterase Domain                                159  5e-38
sp|Q56312|CHEY_THEMA CHEMOTAXIS PROTEIN CHEY >gi|7443033|pir||B7...    96  5e-19
emb|CAA53764.1| (X76170) cheY [Listeria monocytogenes]                 95  1e-18
gi|11498647 chemotaxis response regulator (cheY) [Archaeoglobus ...    87  2e-16
gb|AAC27631.1| (AF076485) defective in fruiting DifD [Myxococcus...    87  4e-16
pir||E71160 probable chemotaxis protein (cheY) - Pyrococcus hori...    85  9e-16
pir||F75002 chemotaxis response regulator (chey) PAB1330 - Pyroc...    85  1e-15
dbj|BAB06687.1| (AP001517) two-component response regulator invo...    84  3e-15
dbj|BAB06163.1| (AP001515) two-component response regulator invo...    82  1e-14
sp|P45709|CCDB_BACSU CCDB PROTEIN >gi|1361404|pir||S57405 respon...    81  2e-14
emb|CAB99140.1| (AL390188) putative two-component system respons...    81  2e-14
sp|P24072|CHEY_BACSU CHEMOTAXIS PROTEIN CHEY HOMOLOG >gi|98251|p...    80  4e-14
sp|P54662|DEGU_BACBR TRANSCRIPTIONAL REGULATORY PROTEIN DEGU >gi...    78  2e-13
pir||T35758 probable response regulator - Streptomyces coelicolo...    78  2e-13
sp|P52931|SP0A_BACCI STAGE 0 SPORULATION PROTEIN A >gi|497953|gb...    77  3e-13
pir||S60871 phosphorylation-activated transcription factor Spo0A...    77  3e-13
sp|P52934|SP0A_BACST STAGE 0 SPORULATION PROTEIN A >gi|2654216|e...    77  3e-13
gb|AAD16452.1| (AF102271) response-regulator [Streptomyces coeli...    76  5e-13
dbj|BAB07347.1| (AP001519) two-component response regulator invo...    76  8e-13
sp|P55184|YXJL_BACSU HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN G...    75  1e-12
emb|CAA63989.1| (X94328) spo0a [Clostridium difficile]                 75  1e-12
sp|P52938|SP0A_CLODI STAGE 0 SPORULATION PROTEIN A HOMOLOG >gi|1...    75  1e-12
pir||H70558 hypothetical protein Rv1626 - Mycobacterium tubercul...    75  1e-12
pir||T34653 probable response regulator - Streptomyces coelicolo...    75  1e-12
emb|CAB59507.1| (AL132648) putative two-component response regul...    75  1e-12
pir||T36318 two-component response regulator - Streptomyces coel...    75  2e-12
pir||T36530 probable two-component system regulator - Streptomyc...    75  2e-12
pir||A70080 two-component response regulator [YxjM] homolog yxjL...    74  2e-12
pir||G69780 two-component response regulator [YdfH] homolog ydfI...    74  2e-12
pir||T35281 probable two component response regulator - Streptom...    74  2e-12
pir||H75381 DNA-binding response regulator - Deinococcus radiodu...    74  2e-12
emb|CAB54571.1| (AJ006393) response regulator [Streptococcus pne...    73  4e-12
emb|CAB87987.1| (AJ288948) Spo0A protein [Clostridium cellulolyt...    73  4e-12
pir||T36528 probable two-component system regulator - Streptomyc...    73  4e-12
pir||T30314 chpB protein - Pseudomonas aeruginosa >gi|11351447|p...    73  5e-12
pir||T35166 probable two-component regulator - Streptomyces coel...    73  5e-12
pir||T36862 probable two-component response regulator - Streptom...    73  5e-12
sp|P33356|YEHT_ECOLI HYPOTHETICAL 27.9 KD PROTEIN IN MOLR-BGLX I...    73  7e-12
gb|AAC33471.1| (AF074950) CheY [Treponema denticola]                   73  7e-12
pdb|1DZ3|A Chain A, Domain-Swapping In The Sporulation Response ...    73  7e-12
emb|CAB90919.1| (AL355774) putative DNA-binding response regulat...    73  7e-12
emb|CAB95289.1| (AL359779) putative two component system respons...    73  7e-12
sp|P37478|YYCF_BACSU HYPOTHETICAL 27.2 KD SENSORY TRANSDUCTION P...    72  9e-12
pir||S58645 response regulator cheY [validated] - Halobacterium ...    72  9e-12
pir||I40540 vsrD protein - Pseudomonas solanacearum >gi|603069|g...    72  1e-11
dbj|BAA88407.1| (AB016841) chiR [Streptomyces thermoviolaceus]         72  1e-11
dbj|BAB05816.1| (AP001514) two-component response regulator [Bac...    72  1e-11
gb|AAB07804.1| (U01971) MtrA [Mycobacterium tuberculosis]              71  2e-11
pir||H70592 probable mtrA protein - Mycobacterium tuberculosis (...    71  2e-11
pir||T34675 probable response regulator - Streptomyces coelicolo...    71  2e-11
sp|P52932|SP0A_BACME STAGE 0 SPORULATION PROTEIN A >gi|497955|gb...    71  3e-11
pir||F70645 hypothetical protein Rv3133c - Mycobacterium tubercu...    71  3e-11
pir||S60872 phosphorylation-activated transcription factor Spo0A...    71  3e-11
pir||F75593 DNA-binding response regulator - Deinococcus radiodu...    71  3e-11
pir||C81104 transcription regulator, LuxR family NMB1250 [import...    71  3e-11
pir||H82218 transcription regulator LuxR family VC1277 [imported...    71  3e-11
dbj|BAB05842.1| (AP001514) two-component response regulator [Bac...    71  3e-11
dbj|BAB05932.1| (AP001514) two-component response regulator [Bac...    71  3e-11
dbj|BAB07746.1| (AP001520) two-component response regulator [Bac...    71  3e-11
sp|P52940|SP0A_CLOPA STAGE 0 SPORULATION PROTEIN A HOMOLOG >gi|4...    70  3e-11
pir||S60880 phosphorylation-activated transcription factor Spo0A...    70  3e-11
pir||E75450 DNA-binding response regulator - Deinococcus radiodu...    70  3e-11
sp|P13800|DEGU_BACSU TRANSCRIPTIONAL REGULATORY PROTEIN DEGU (PR...    70  4e-11
pdb|1QMP|A Chain A, Phosphorylated Aspartate In The Crystal Stru...    70  4e-11
emb|CAB64972.1| (AJ012050) VicR protein [Enterococcus faecalis]        70  4e-11
sp|P52929|SP0A_BACBR STAGE 0 SPORULATION PROTEIN A >gi|2119860|p...    69  6e-11
pir||T35199 probable two-component regulator - Streptomyces coel...    69  6e-11
dbj|BAB07561.1| (AP001520) two-component response regulator [Bac...    69  6e-11
sp|P96126|CHEY_TREPA CHEMOTAXIS PROTEIN CHEY >gi|7443016|pir||D7...    69  8e-11
gi|11467627 ompR homolog [Guillardia theta] >gi|6136611|sp|O7842...    69  8e-11
pir||T36543 probable two-component system regulator - Streptomyc...    69  8e-11

>pir||E75002 protein-glutamate methylesterase (cheb) PAB1331 - Pyrococcus abyssi
           (strain Orsay) >gi|5458973|emb|CAB50459.1| (AJ248288)
           protein-glutamate methylesterase (cheB) [Pyrococcus
           abyssi]
           Length = 368
           
 Score =  721 bits (1841), Expect = 0.0
 Identities = 368/368 (100%), Positives = 368/368 (100%)

Query: 1   MPLTGRKIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLD 60
           MPLTGRKIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLD
Sbjct: 1   MPLTGRKIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLD 60

Query: 61  VEMPRMNGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINM 120
           VEMPRMNGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINM
Sbjct: 61  VEMPRMNGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINM 120

Query: 121 RELKDEIIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSL 180
           RELKDEIIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSL
Sbjct: 121 RELKDEIIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSL 180

Query: 181 LKIFPKFPENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPG 240
           LKIFPKFPENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPG
Sbjct: 181 LKIFPKFPENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPG 240

Query: 241 DYHMEVTLRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQG 300
           DYHMEVTLRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQG
Sbjct: 241 DYHMEVTLRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQG 300

Query: 301 IVEIKKRGGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKIPETVVRAVEMIRGGGNL 360
           IVEIKKRGGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKIPETVVRAVEMIRGGGNL
Sbjct: 301 IVEIKKRGGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKIPETVVRAVEMIRGGGNL 360

Query: 361 GRHVTIPR 368
           GRHVTIPR
Sbjct: 361 GRHVTIPR 368


>sp|O58192|CHEB_PYRHO PROTEIN-GLUTAMATE METHYLESTERASE >gi|7435070|pir||F71160
           hypothetical protein PH0483 - Pyrococcus horikoshii
           >gi|3256888|dbj|BAA29571.1| (AP000002) 368aa long
           hypothetical protein-glutamate methylesterase
           [Pyrococcus horikoshii]
           Length = 368
           
 Score =  701 bits (1790), Expect = 0.0
 Identities = 356/368 (96%), Positives = 365/368 (98%)

Query: 1   MPLTGRKIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLD 60
           MPL GRKI+VLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLD
Sbjct: 1   MPLMGRKIKVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLD 60

Query: 61  VEMPRMNGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINM 120
           VEMPRMNGLDALRVIMK+YPVPVIMISALTQEGA+ATIKALEYGAIDFIPKPSSSISINM
Sbjct: 61  VEMPRMNGLDALRVIMKRYPVPVIMISALTQEGADATIKALEYGAIDFIPKPSSSISINM 120

Query: 121 RELKDEIIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSL 180
           +ELKDEIIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSL
Sbjct: 121 KELKDEIIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSL 180

Query: 181 LKIFPKFPENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPG 240
           LKIFPKFPE+LKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPG
Sbjct: 181 LKIFPKFPEDLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPG 240

Query: 241 DYHMEVTLRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQG 300
           DYHMEVTLR GKPVITLNKKPK+HGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQG
Sbjct: 241 DYHMEVTLRAGKPVITLNKKPKIHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQG 300

Query: 301 IVEIKKRGGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKIPETVVRAVEMIRGGGNL 360
           IVEIKK+GGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKIPETVV+AVE+IRGGGNL
Sbjct: 301 IVEIKKKGGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKIPETVVKAVEIIRGGGNL 360

Query: 361 GRHVTIPR 368
           GRHVTI R
Sbjct: 361 GRHVTISR 368


>sp|Q9WYN9|CHEB_THEMA PROTEIN-GLUTAMATE METHYLESTERASE >gi|7435065|pir||F72380
           protein-glutamate methylesterase - Thermotoga maritima
           (strain MSB8) >gi|4980913|gb|AAD35493.1|AE001720_7
           (AE001720) protein-glutamate methylesterase [Thermotoga
           maritima]
           Length = 344
           
 Score =  353 bits (896), Expect = 2e-96
 Identities = 174/349 (49%), Positives = 249/349 (70%), Gaps = 5/349 (1%)

Query: 3   LTGRKIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVE 62
           +T R IRVLVVDDSAFMR VLKDII+S P+++V G A+DG+EA+E   + +PDV+T+D+E
Sbjct: 1   MTDRVIRVLVVDDSAFMRMVLKDIIDSQPDMKVVGFAKDGLEAVEKAIELKPDVITMDIE 60

Query: 63  MPRMNGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRE 122
           MP +NG++AL++IMKK P  VIM+S+LT+EGA  TI+AL  GA+DFI KP  SIS+  R+
Sbjct: 61  MPNLNGIEALKLIMKKAPTRVIMVSSLTEEGAAITIEALRNGAVDFITKPHGSISLTFRQ 120

Query: 123 LKDEIIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSLLK 182
           +  E++ KI++A  V  R L  +     +V +    KP+V  +I V I +STGGP+SL  
Sbjct: 121 VAPELLEKIRQAMNVDPRTLLFKP----KVSRLTITKPAVSGKIVV-IGSSTGGPRSLDM 175

Query: 183 IFPKFPENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPGDY 242
           I P  P+N  A I++VQHMPPGFT+S A RLDS S++ VKEAE+G+ V+ G  Y+APGD+
Sbjct: 176 IIPNLPKNFPAPIVVVQHMPPGFTKSLAMRLDSTSELTVKEAEDGEEVKPGFVYIAPGDF 235

Query: 243 HMEVTLRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQGIV 302
           H+ +  + GK    L+K  K++ VRPA D  +  AA+++  +T+ V++TGMG+DG +G  
Sbjct: 236 HLGLKAQNGKVFFFLDKSDKINNVRPAVDFTLDKAAEIYKSKTIAVILTGMGKDGTKGAF 295

Query: 303 EIKKRGGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKIPETVVRAV 351
           ++K  GG  IA+D++T ++FGMPK+ IE G  DYV+P  KIPE ++  V
Sbjct: 296 KVKFYGGTVIAEDKETCVVFGMPKSVIEEGYADYVLPAYKIPEKLIELV 344


>pir||F83623 probable methylesterase PA0173 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9946006|gb|AAG03563.1|AE004455_4
           (AE004455) probable methylesterase [Pseudomonas
           aeruginosa]
           Length = 349
           
 Score =  302 bits (765), Expect = 4e-81
 Identities = 157/352 (44%), Positives = 232/352 (65%), Gaps = 7/352 (1%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           I VLVVDDSA +R +LK+II +DPEL + G A D   A +++++  PDV++LDVEMPRM+
Sbjct: 3   ISVLVVDDSALIRSLLKEIIQADPELRLVGCAPDAFVARDLIKQHAPDVISLDVEMPRMD 62

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEI 127
           GL  L  +MK  P PV+MIS+LT+ G+EAT++ALE GA+DFI KP   I+  M+   +EI
Sbjct: 63  GLTFLDKLMKARPTPVLMISSLTERGSEATLRALELGAVDFIAKPRLGIAEGMQAYAEEI 122

Query: 128 IAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSLLKIFPKF 187
            AK+K  A+       LRR         +   P +     +A+ ASTGG ++L ++    
Sbjct: 123 RAKLKTVARA-----RLRRRAADAPAPPESAAPLLSTEKIIALGASTGGTEALKEVLLGL 177

Query: 188 PENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPGDYHMEVT 247
           P +   G+++ QHMPPGFTRSFA+RLD ++++ V EA +GD +  G A VAPGD+HMEV 
Sbjct: 178 PAH-SPGVVITQHMPPGFTRSFAERLDRLTRLSVSEARDGDRILPGHALVAPGDHHMEVQ 236

Query: 248 LRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQGIVEIKKR 307
             G   V+ LN++ +++G RPA D M  + A+  GR  +  ++TGMG+DGA+G++ I++ 
Sbjct: 237 RSGANYVVRLNRQAQVNGHRPAVDVMFESLARCAGRNLLAGLLTGMGKDGARGLLAIRQA 296

Query: 308 GGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKIPETVVRAVEMIRGGGN 359
           GG T+AQDE T +++GMP+ A+E G  + V+PLE+I   +++     RG GN
Sbjct: 297 GGYTLAQDEATCVVYGMPREAVELGAAEDVLPLERIAAALLQQAAR-RGSGN 347


>gi|11498646 protein-glutamate methylesterase (cheB) [Archaeoglobus fulgidus]
           >gi|7531056|sp|O29221|CHEB_ARCFU PROTEIN-GLUTAMATE
           METHYLESTERASE >gi|7435066|pir||A69380 protein-glutamate
           methylesterase (EC 3.1.1.61) cheB - Archaeoglobus
           fulgidus >gi|2649549|gb|AAB90199.1| (AE001031)
           protein-glutamate methylesterase (cheB) [Archaeoglobus
           fulgidus]
           Length = 349
           
 Score =  291 bits (737), Expect = 9e-78
 Identities = 146/346 (42%), Positives = 225/346 (64%), Gaps = 2/346 (0%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           +RVLVVDDSA +R  + DI+     +EV   A++G EA+E   K +PDV+TLD+ MP M+
Sbjct: 1   MRVLVVDDSALVRMAVTDILTK-AGIEVVDTAKNGREAVEKALKLKPDVITLDINMPEMD 59

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEI 127
           GL AL++IM+K P PV+M+S+LT+EGA  T++AL+ GA+DF+ KP  ++ +++  +  E+
Sbjct: 60  GLTALKLIMEKQPTPVVMLSSLTKEGARETLEALKIGAVDFVTKPDGAL-VDLSSVAQEL 118

Query: 128 IAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSLLKIFPKF 187
           + K++ AA      L L+ ++ ++ +  +         + V I +STGGP +L  I P+ 
Sbjct: 119 VRKVQMAASTSLNVLRLQNLKKIKGEVVRGNWKGKTKDVCVLIGSSTGGPSALEMIIPRL 178

Query: 188 PENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPGDYHMEVT 247
           P ++ A + +VQHMPPGFT+  A+RL+S+S+++VKEAE  + V++G  YVAPG YHM+V 
Sbjct: 179 PADIPAPVFVVQHMPPGFTKQLAERLNSISEVEVKEAENNERVKDGVVYVAPGGYHMKVR 238

Query: 248 LRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQGIVEIKKR 307
                  I +     ++ V+P+ D    +  Q +G   VG ++TGMG DGA G+  IK R
Sbjct: 239 RAANVVRIKVVDGEPVNAVKPSVDVTADSVVQAYGGNVVGAILTGMGEDGAYGMKLIKDR 298

Query: 308 GGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKIPETVVRAVEM 353
           GG+TIA  E T ++FGMPKAAIE G +  V P+ +I E +VR +E+
Sbjct: 299 GGLTIASSEDTCMVFGMPKAAIELGGITSVKPVFEIAEEIVRFLEV 344


>dbj|BAB06154.1| (AP001515) MCP-glutamate methylesterase / two-component response
           regulator [Bacillus halodurans]
           Length = 346
           
 Score =  288 bits (730), Expect = 6e-77
 Identities = 146/343 (42%), Positives = 225/343 (65%), Gaps = 4/343 (1%)

Query: 7   KIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRM 66
           +I+VLVVDDSAFMRKV+  ++ SDP LEV G AR+G +A++  +   PDV+TLDVEMP M
Sbjct: 4   RIKVLVVDDSAFMRKVITSMLESDPRLEVVGTARNGEDALKKRKTLAPDVMTLDVEMPVM 63

Query: 67  NGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDE 126
           +G++ L+ +M + P+P+I++S+ T+EGAE  + A+E GA+DFI KPS  IS+++ +++D 
Sbjct: 64  DGIETLKRLMSENPLPIIIVSSTTKEGAENALTAMELGAVDFITKPSGPISLDLEKVRDL 123

Query: 127 IIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSLLKIFPK 186
           +I K+  A  V  +    +   + R  +    +P    +  + I  STGGP++L ++  K
Sbjct: 124 LIEKVASAPNVKLKPTSKKAPVVFRPLQ----QPVPFDKTIIVIGTSTGGPKALKQVLTK 179

Query: 187 FPENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPGDYHMEV 246
            P++L A IL+VQHMP GFT S A RL+S+ +I VKEAE+G+++  G AY+APG YH+E 
Sbjct: 180 LPKDLPAPILIVQHMPAGFTESLANRLNSLCEIHVKEAEDGEIIRPGVAYIAPGGYHLET 239

Query: 247 TLRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQGIVEIKK 306
              G    + L K+    G RP+ D +  + + +     V V+MTGMG DG +G+ ++K+
Sbjct: 240 KRLGTSIALHLTKEEPRKGHRPSVDVLFESVSALSSIYKVAVIMTGMGSDGTEGLEQLKR 299

Query: 307 RGGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKIPETVVR 349
                IA+ E++ ++FGMPK AIE  +VD V  LE I +++VR
Sbjct: 300 GSCYAIAESEQSCVVFGMPKVAIERKLVDEVTHLELIADSIVR 342


>sp|P07330|CHEB_ECOLI PROTEIN-GLUTAMATE METHYLESTERASE >gi|67229|pir||XYECEB
           protein-glutamate methylesterase (EC 3.1.1.61) -
           Escherichia coli >gi|1736536|dbj|BAA15699.1| (D90830)
           Protein-glutamate methylesterase (EC 3.1.1.61).
           [Escherichia coli] >gi|1788192|gb|AAC74953.1| (AE000282)
           response regulator for chemotaxis (cheA sensor); protein
           methylesterase [Escherichia coli K12]
           Length = 349
           
 Score =  279 bits (706), Expect = 4e-74
 Identities = 147/345 (42%), Positives = 221/345 (63%), Gaps = 6/345 (1%)

Query: 7   KIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRM 66
           KIRVL VDDSA MR+++ +IINS  ++E+   A D + A ++++K  PDV+TLDVEMPRM
Sbjct: 3   KIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDLIKKFNPDVLTLDVEMPRM 62

Query: 67  NGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDE 126
           +GLD L  +M+  P+PV+M+S+LT +G+E T++ALE GAIDF+ KP   I   M    + 
Sbjct: 63  DGLDFLEKLMRLRPMPVVMVSSLTGKGSEVTLRALELGAIDFVTKPQLGIREGMLAYNEM 122

Query: 127 IIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSLLKIFPK 186
           I  K++ AAK       L   + L      K  P + +   +AI ASTGG +++  +   
Sbjct: 123 IAEKVRTAAKA-----SLAAHKPLSAPTTLKAGPLLSSEKLIAIGASTGGTEAIRHVLQP 177

Query: 187 FPENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPGDYHMEV 246
            P +  A +L+ QHMPPGFTRSFA RL+ + +I VKEAE+G+ V  G AY+APGD HME+
Sbjct: 178 LPLSSPA-LLITQHMPPGFTRSFADRLNKLCQIGVKEAEDGERVLPGHAYIAPGDRHMEL 236

Query: 247 TLRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQGIVEIKK 306
           +  G    I ++  P ++  RP+ D +  + A+  GR  VGV++TGMG DGA G++ +++
Sbjct: 237 SRSGANYQIKIHDGPAVNRHRPSVDVLFHSVAKQAGRNAVGVILTGMGNDGAAGMLAMRQ 296

Query: 307 RGGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKIPETVVRAV 351
            G  T+AQ+E + ++FGMP+ AI  G V  VV L ++ + ++  +
Sbjct: 297 AGAWTLAQNEASCVVFGMPREAINMGGVCEVVDLSQVSQQMLAKI 341


>gb|AAA23569.1| (M13463) cheB peptide [Escherichia coli]
           Length = 349
           
 Score =  277 bits (701), Expect = 1e-73
 Identities = 146/345 (42%), Positives = 220/345 (63%), Gaps = 6/345 (1%)

Query: 7   KIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRM 66
           KIRVL VDDSA MR+++ +IINS  ++E+   A D + A ++++K  PDV+TLDVEMPRM
Sbjct: 3   KIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDLIKKFNPDVLTLDVEMPRM 62

Query: 67  NGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDE 126
           +GLD L  +M+  P+PV+M+S+LT +G+E T++ LE GAIDF+ KP   I   M    + 
Sbjct: 63  DGLDFLEKLMRLRPMPVVMVSSLTGKGSEVTLRPLELGAIDFVTKPQLGIREGMLAYNEM 122

Query: 127 IIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSLLKIFPK 186
           I  K++ AAK       L   + L      K  P + +   +AI ASTGG +++  +   
Sbjct: 123 IAQKVRTAAKA-----SLAAHKPLSAPTTLKAGPLLSSEKLIAIGASTGGTEAIRHVLQP 177

Query: 187 FPENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPGDYHMEV 246
            P +  A +L+ QHMPPGFTRSFA RL+ + +I VKEAE+G+ V  G AY+APGD HME+
Sbjct: 178 LPLSSPA-LLITQHMPPGFTRSFADRLNKLCQIGVKEAEDGERVLPGHAYIAPGDRHMEL 236

Query: 247 TLRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQGIVEIKK 306
           +  G    I ++  P ++  RP+ D +  + A+  GR  VGV++TGMG DGA G++ +++
Sbjct: 237 SRSGANYQIKIHDGPAVNRHRPSVDVLFHSVAKQAGRNAVGVILTGMGNDGAAGMLAMRQ 296

Query: 307 RGGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKIPETVVRAV 351
            G  T+AQ+E + ++FGMP+ AI  G V  VV L ++ + ++  +
Sbjct: 297 AGAWTLAQNEASCVVFGMPREAINMGGVCEVVDLSQVSQQMLAKI 341


>sp|P04042|CHEB_SALTY PROTEIN-GLUTAMATE METHYLESTERASE >gi|67228|pir||XYEBET
           protein-glutamate methylesterase (EC 3.1.1.61) -
           Salmonella typhimurium >gi|3212266|pdb|1A2O|A Chain A,
           Structural Basis For Methylesterase Cheb Regulation By A
           Phosphorylation-Activated Domain >gi|3212267|pdb|1A2O|B
           Chain B, Structural Basis For Methylesterase Cheb
           Regulation By A Phosphorylation-Activated Domain
           Length = 349
           
 Score =  277 bits (700), Expect = 2e-73
 Identities = 144/345 (41%), Positives = 220/345 (63%), Gaps = 6/345 (1%)

Query: 7   KIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRM 66
           KIRVL VDDSA MR+++ +IINS  ++E+   A D + A ++++K  PDV+TLDVEMPRM
Sbjct: 3   KIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDLIKKFNPDVLTLDVEMPRM 62

Query: 67  NGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDE 126
           +GLD L  +M+  P+PV+M+S+LT +G+E T++ALE GAIDF+ KP   I   M    + 
Sbjct: 63  DGLDFLEKLMRLRPMPVVMVSSLTGKGSEVTLRALELGAIDFVTKPQLGIREGMLAYSEM 122

Query: 127 IIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSLLKIFPK 186
           I  K++ AA+       +   + +      K  P + +   +AI ASTGG +++  +   
Sbjct: 123 IAEKVRTAARA-----RIAAHKPMAAPTTLKAGPLLSSEKLIAIGASTGGTEAIRHVLQP 177

Query: 187 FPENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPGDYHMEV 246
            P +  A +++ QHMPPGFTRSFA+RL+ + +I VKEAE+G+ V  G AY+APGD HME+
Sbjct: 178 LPLSSPA-VIITQHMPPGFTRSFAERLNKLCQISVKEAEDGERVLPGHAYIAPGDKHMEL 236

Query: 247 TLRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQGIVEIKK 306
              G    I ++  P ++  RP+ D +  + A+  GR  VGV++TGMG DGA G++ + +
Sbjct: 237 ARSGANYQIKIHDGPPVNRHRPSVDVLFHSVAKHAGRNAVGVILTGMGNDGAAGMLAMYQ 296

Query: 307 RGGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKIPETVVRAV 351
            G  TIAQ+E + ++FGMP+ AI  G V  VV L ++ + ++  +
Sbjct: 297 AGAWTIAQNEASCVVFGMPREAINMGGVSEVVDLSQVSQQMLAKI 341


>dbj|BAB15840.1| (AB040876) CheB [Enterobacter cloacae]
           Length = 350
           
 Score =  272 bits (688), Expect = 5e-72
 Identities = 144/337 (42%), Positives = 214/337 (62%), Gaps = 6/337 (1%)

Query: 7   KIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRM 66
           KIRVL VDDSA MR+++ +IINS  ++E+   A D + A ++++K  PDV+TLDVEMPRM
Sbjct: 3   KIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDLIKKYNPDVLTLDVEMPRM 62

Query: 67  NGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDE 126
           +G+D L  +M+  P+PV+M+S+LT +G+E T++ALE GA+DF+ KP   I   M    + 
Sbjct: 63  DGIDFLEKLMRLRPMPVVMVSSLTGKGSEITLRALELGAVDFVTKPQLGIREGMLAYSEM 122

Query: 127 IIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSLLKIFPK 186
           I  KI+  ++      +L     L      K  P + +   + I ASTGG +++  +   
Sbjct: 123 IAEKIRHPSRA-----KLAAHTPLAAPDTLKAGPLLSSEKLLVIGASTGGTEAIRHVLQP 177

Query: 187 FPENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPGDYHMEV 246
            P +   GIL+ QHMPPGFTRSFA+RL+ + +I VKEAE+G+ V  G AY+APGD HME+
Sbjct: 178 LPLS-SPGILITQHMPPGFTRSFAERLNKLCQISVKEAEDGERVPPGHAYIAPGDKHMEL 236

Query: 247 TLRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQGIVEIKK 306
           + R     I ++  P ++  RP+ D +  + A+  GR  VGV++TGMG DGA G++ +  
Sbjct: 237 SRRRANYQIKIHDGPPVNRHRPSVDVLFHSVAKHAGRNAVGVILTGMGNDGAAGMLAMPI 296

Query: 307 RGGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKI 343
            G  TIAQ+E + ++FGMP+ AI  G V  VV L ++
Sbjct: 297 AGAWTIAQNEASCVVFGMPREAINMGGVSEVVDLSQV 333


>sp|Q05522|CHEB_BACSU PROTEIN-GLUTAMATE METHYLESTERASE >gi|1075896|pir||A48511
           protein-glutamate methylesterase (EC 3.1.1.61) cheB -
           Bacillus subtilis >gi|580836|emb|CAA48007.1| (X67806)
           CheB [Bacillus subtilis] >gi|2634014|emb|CAB13515.1|
           (Z99112) methyl-accepting chemotaxis proteins
           (MCP)-glutamate methylesterase and two-component
           response regulator-like [Bacillus subtilis]
           Length = 357
           
 Score =  267 bits (676), Expect = 1e-70
 Identities = 142/358 (39%), Positives = 226/358 (62%), Gaps = 13/358 (3%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           IRVLVVDDSAFMRK++ D +  + ++EV G AR+G EA++ ++  +PDV+TLDVEMP MN
Sbjct: 2   IRVLVVDDSAFMRKMISDFLTEEKQIEVIGTARNGEEALKKIELLKPDVITLDVEMPVMN 61

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEI 127
           G D +R I++ Y +PVIM+S+ T++G E TI  LE GA DFI KPS SIS+++ ++K+++
Sbjct: 62  GTDTVRKIIEIYNLPVIMVSSQTEKGKECTINCLEIGAFDFITKPSGSISLDLYKIKEQL 121

Query: 128 IAKIKEAAKVPRRFLELRR-------IRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSL 180
           + ++  A    +R   + +       +R +   +  K KP    +I V I  STGGP++L
Sbjct: 122 VERVVAAGLSGKRKRPVSQTVRPEPIVRAVVKPELSKPKPGTGRQI-VCIGTSTGGPRAL 180

Query: 181 LKIFPKFPENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPG 240
            K+ PK P++L A +++VQHMP GFT S A RL+ +S I VKEA++G+    G  Y+APG
Sbjct: 181 QKVIPKLPKDLNAPVVVVQHMPEGFTASLADRLNHLSDIQVKEAKDGEAALNGCVYIAPG 240

Query: 241 DYHMEV--TLRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGA 298
             ++ V     G + V+  +  P  H  +P+AD +  +  ++     V V+MTGMG DG 
Sbjct: 241 GKNISVIKNSEGLQVVLDNHDTPSRH--KPSADYLFRSVGKLTDYEKVAVIMTGMGSDGT 298

Query: 299 QGIVEIKKRGGI-TIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKIPETVVRAVEMIR 355
            G+ ++   G +  IA+ E++ +++GMPKAA++ G++  +  +E I  ++   V+  R
Sbjct: 299 AGLKDMLTAGNVKAIAESEESCVVYGMPKAAVKAGLIHEIKHVEDIAASITSCVKKER 356


>sp|O87717|CHEB_CAUCR PROTEIN-GLUTAMATE METHYLESTERASE >gi|3387366|emb|CAA07180.1|
           (AJ006687) CheB [Caulobacter crescentus]
           Length = 344
           
 Score =  265 bits (669), Expect = 8e-70
 Identities = 149/343 (43%), Positives = 210/343 (60%), Gaps = 9/343 (2%)

Query: 7   KIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRM 66
           KIRVLVVDDSA MR ++   +N DP++EV G A D  EA  M++   PDVVTLD+EMP M
Sbjct: 3   KIRVLVVDDSATMRSLISAALNRDPDIEVVGGAGDPFEARGMIKALNPDVVTLDIEMPNM 62

Query: 67  NGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDE 126
           NG+D L  IM+  P+PV+M+S LTQ GAE T++ALE GA+D + KP+   +   +E   E
Sbjct: 63  NGIDFLEKIMRLRPMPVVMVSTLTQAGAEMTLRALELGAVDCVGKPAD--ATGTQEALAE 120

Query: 127 IIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSLLKIFPK 186
           I+AK+K AA+   R                + K  +P+   VAI +STGG ++LL I   
Sbjct: 121 IVAKVKIAARASVR----TNAGAAPTSAPTRRKDFMPSGDIVAIGSSTGGVEALLSILQL 176

Query: 187 FPENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPGD-YHME 245
           FPE     + + QHMP  FT SFA RLD  S   V+EA +G ++E GK YVAPG   H+E
Sbjct: 177 FPETCPPTV-ITQHMPATFTASFAARLDRSSGAKVQEASDGALLEPGKVYVAPGGATHLE 235

Query: 246 VTLRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQGIVEIK 305
           V    G     +   P + G RP+ D +  + A   G + VGV++TGMGRDGAQG++ ++
Sbjct: 236 VVRSAGLRCRLVAGDP-VSGHRPSVDVLFNSVAHAVGDKAVGVILTGMGRDGAQGLLTMR 294

Query: 306 KRGGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKIPETVV 348
           K G  T+ QDE + +++GMP++A E G V+  V L  + ++++
Sbjct: 295 KAGAKTLGQDEASCVVYGMPRSAFEIGAVERQVSLSSMGQSIL 337


>sp|Q52883|CHEB_RHIME PROTEIN-GLUTAMATE METHYLESTERASE >gi|2120799|pir||S61837
           protein-glutamate methylesterase (EC 3.1.1.61) cheB -
           Rhizobium meliloti >gi|534840|gb|AAA86677.1| (U13166)
           CheB [Sinorhizobium meliloti]
           Length = 349
           
 Score =  262 bits (663), Expect = 4e-69
 Identities = 146/350 (41%), Positives = 213/350 (60%), Gaps = 9/350 (2%)

Query: 9   RVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMNG 68
           RVLVVDDSA MR ++  ++N+DP++ V G+A D +EA + +++  PDVVTLD+EMP MNG
Sbjct: 6   RVLVVDDSATMRGLISAVLNADPDISVVGQAADALEARQAIKQLDPDVVTLDIEMPNMNG 65

Query: 69  LDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEII 128
           L+ L  IM+  P+PVIM+S LT  GAEATI ALE GA D + KP        R+L D   
Sbjct: 66  LEFLDKIMRLRPMPVIMVSTLTHRGAEATIAALEIGAFDCVGKPQPGDPHPFRDLAD--- 122

Query: 129 AKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSLLKIFPKFP 188
            K+K AA+  R+   +          A  V      R  VAI ASTGG ++L+ +  KFP
Sbjct: 123 -KVKAAARSQRK--SMITSNRAAAPAATAVSDYRAGRKIVAIGASTGGVEALITVLQKFP 179

Query: 189 ENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAP-GDYHMEVT 247
            N    + + QHMP  FT+SFA+RL+ +    V+EA +G  +E G+ Y+AP G+ H+EV 
Sbjct: 180 ANCPPTV-ITQHMPHTFTKSFAERLNRLCAPTVQEATDGARLEVGRVYLAPGGERHLEVH 238

Query: 248 LRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQGIVEIKKR 307
                P   L   P ++G RP+ D +  + A++ GR  +GV++TGMGRDGA G+++++  
Sbjct: 239 -NAAAPCCRLVDHPPVNGHRPSVDVLFDSVAELAGRNAIGVILTGMGRDGAAGLLKLRHA 297

Query: 308 GGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKIPETVVRAVEMIRGG 357
           G  T  Q+EKT +++GMP+ A E G V+  +PL  I E +++     + G
Sbjct: 298 GARTFGQNEKTCVVYGMPRVAYELGAVETQLPLGSIGEEILKTAAARKEG 347


>sp|O85128|CHEB_AGRTU PROTEIN-GLUTAMATE METHYLESTERASE >gi|3282794|gb|AAC25079.1|
           (AF044495) CheB homolog [Agrobacterium tumefaciens]
           Length = 351
           
 Score =  257 bits (649), Expect = 2e-67
 Identities = 138/352 (39%), Positives = 216/352 (61%), Gaps = 7/352 (1%)

Query: 9   RVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMNG 68
           RVLVVDDS  MR ++  ++ +DPE+EV G+A + +EA   +++  PDVVTLD+EMP MNG
Sbjct: 6   RVLVVDDSPTMRGLISAVLKADPEVEVVGQAGNAMEARAAIKQLNPDVVTLDIEMPEMNG 65

Query: 69  LDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEII 128
           L+ L  IM+  P+PVIM+S+LT  GA+A++ ALE GA D + KP+   +    +L D   
Sbjct: 66  LEFLEKIMRLRPMPVIMVSSLTHRGADASLAALEIGAFDCVGKPAPGDARPFGDLAD--- 122

Query: 129 AKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSLLKIFPKFP 188
            K+K AA+         R       +   +      R  VAI +STGG ++L+ +  KFP
Sbjct: 123 -KVKAAARSQHAAYRATRPETAAAPQPVPMSEYRAGRKVVAIGSSTGGVEALIAVLQKFP 181

Query: 189 ENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPG-DYHMEVT 247
            N    ++  QHMPP FT+SFA+RL+ +    V+EA +G  ++ GK Y+APG + H+++ 
Sbjct: 182 ANCPPTVI-TQHMPPTFTKSFAERLNRICAPVVEEATDGARLQTGKIYLAPGGERHLQIA 240

Query: 248 LRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQGIVEIKKR 307
            R       L++ P ++G RP+ D +  + A++ GR  VGV++TGMGRDGA G+++++  
Sbjct: 241 NRSAPCCRLLDRDP-VNGHRPSVDVLFDSVAELAGRNAVGVILTGMGRDGAAGLLKMRHA 299

Query: 308 GGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKIPETVVRAVEMIRGGGN 359
           G  T+ Q+EKT +++GMP+ A E G V+  +PL  I E +++     + G +
Sbjct: 300 GARTVGQNEKTCVVYGMPRVAYELGAVEQQLPLASIGEEILKLTTARKEGAD 351


>gb|AAG19394.1| (AE005033) chemotaxis protein; CheB [Halobacterium sp. NRC-1]
           Length = 347
           
 Score =  255 bits (644), Expect = 7e-67
 Identities = 137/342 (40%), Positives = 203/342 (59%), Gaps = 4/342 (1%)

Query: 11  LVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMNGLD 70
           LVVDDS FMR V+ DI+  D  ++V G A +G  A++ V   +PDV+T+DVEMP M+G++
Sbjct: 5   LVVDDSHFMRTVISDILE-DGGVDVVGTAENGARALDAVTDVQPDVITMDVEMPEMDGIE 63

Query: 71  ALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEIIAK 130
           A   IM++ P P++M+SALT E A+AT++A+E GAID   KP  +IS  +    +E++A 
Sbjct: 64  ATAEIMREQPTPILMVSALTTEDADATLEAMEKGAIDTFAKPGGTISTELSGHSEELVAA 123

Query: 131 IKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSLLKIFPKFPEN 190
           ++  A           + +                  + I ASTGGP  +  I    P  
Sbjct: 124 VERVASADP--TAGHDVEMEPASPPDATTSEYADNPTLLIGASTGGPNVVESILASLPAE 181

Query: 191 LKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPGDYHMEVT-LR 249
               +L+VQHMP  FT  FA RLD+ S+ D+ EAE+G  +  G+  VA GDYHM V+   
Sbjct: 182 ADFRVLIVQHMPDQFTSRFADRLDAASQYDITEAEDGSRIGGGEGLVARGDYHMRVSGYS 241

Query: 250 GGKPVITLNKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQGIVEIKKRGG 309
            G+  + L++  ++H VRPA D    +AA+      V VV+TGMG DGA G+  +K  GG
Sbjct: 242 NGRLRVRLDQSERLHSVRPAIDVTFKSAAERVTDPLVSVVLTGMGSDGADGVRAVKDAGG 301

Query: 310 ITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKIPETVVRAV 351
            T+AQ+E TS +FG+P+ AIETG VD V+P++++ E +  ++
Sbjct: 302 ATLAQNEATSAVFGIPERAIETGCVDDVLPVDQLTEAIADSI 343


>sp|Q48300|CHEB_HALSA PROTEIN-GLUTAMATE METHYLESTERASE >gi|1363463|pir||S58646
           protein-glutamate methylesterase (EC 3.1.1.61) cheB
           [similarity] - Halobacterium salinarum
           >gi|994803|emb|CAA60162.1| (X86407) cheB [Halobacterium
           salinarum]
           Length = 347
           
 Score =  255 bits (644), Expect = 7e-67
 Identities = 137/342 (40%), Positives = 203/342 (59%), Gaps = 4/342 (1%)

Query: 11  LVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMNGLD 70
           LVVDDS FMR V+ DI+  D  ++V G A +G  A++ V   +PDV+T+DVEMP M+G++
Sbjct: 5   LVVDDSHFMRTVISDILE-DGGVDVVGTAENGARALDAVTDVQPDVITMDVEMPEMDGIE 63

Query: 71  ALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEIIAK 130
           A   IM++ P P++M+SALT E A+AT++A+E GAID   KP  +IS  +    +E++A 
Sbjct: 64  ATAEIMREQPTPILMVSALTTEDADATLEAMEKGAIDTFAKPGGTISTELSGHSEELVAA 123

Query: 131 IKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSLLKIFPKFPEN 190
           ++  A           + +                  + I ASTGGP  +  I    P  
Sbjct: 124 VERVASADP--TAGHDVEMEPASPPDATTSEYADNPTLLIGASTGGPNVVESILASLPAE 181

Query: 191 LKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPGDYHMEVT-LR 249
               +L+VQHMP  FT  FA RLD+ S+ D+ EAE+G  +  G+  VA GDYHM V+   
Sbjct: 182 ADFRVLIVQHMPDQFTSRFADRLDAASQYDITEAEDGSRIGGGEGLVARGDYHMRVSGYS 241

Query: 250 GGKPVITLNKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQGIVEIKKRGG 309
            G+  + L++  ++H VRPA D    +AA+      V VV+TGMG DGA G+  +K  GG
Sbjct: 242 NGRLRVRLDQSERLHSVRPAIDVTFKSAAERVTDPLVSVVLTGMGSDGADGVRPVKDAGG 301

Query: 310 ITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKIPETVVRAV 351
            T+AQ+E TS +FG+P+ AIETG VD V+P++++ E +  ++
Sbjct: 302 ATLAQNEATSAVFGIPERAIETGCVDDVLPVDQLTEAIADSI 343


>pir||H82122 protein-glutamate methylesterase CheB VC2062 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9656608|gb|AAF95208.1| (AE004280) protein-glutamate
           methylesterase CheB [Vibrio cholerae]
           Length = 377
           
 Score =  244 bits (617), Expect = 1e-63
 Identities = 140/373 (37%), Positives = 213/373 (56%), Gaps = 36/373 (9%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           I+VLVVDDS+F R+ + +IINS+  LEV   A +G EA+E   + +PDV+T+D+EMP M+
Sbjct: 3   IKVLVVDDSSFFRRRVSEIINSESRLEVIDVAVNGKEAVEKAARLKPDVITMDIEMPVMD 62

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEI 127
           G+ A+R IM   PVP++M S+LT +GA+AT+ AL+ GA+DF+PK    I+ N    +DE 
Sbjct: 63  GISAVREIMANNPVPILMFSSLTHDGAKATLDALDAGALDFLPKKFEDIARN----RDEA 118

Query: 128 IAKIKE-AAKVPRRFLELRRIRLLR-------------------------------VQKA 155
           +  +++    +  + + LRR    R                               V  A
Sbjct: 119 VTLLQQRVLSIASKKMFLRRPAAPRPAPTTSIAASSSLSQERAAATSPLGNRPSTAVSAA 178

Query: 156 KKVKPSVPARIAVAIAASTGGPQSLLKIFPKFPENLKAGILLVQHMPPGFTRSFAKRLDS 215
            + K S       AI  STGGP +L KI  K P N    I+L+QHMP  FT +FA RL+S
Sbjct: 179 TRFKASGKKYQLTAIGTSTGGPVALQKILTKLPVNYPHPIVLIQHMPATFTAAFASRLNS 238

Query: 216 VSKIDVKEAEEGDVVEEGKAYVAPGDYHMEVTLRGGKPVITLNKKPKMHGVRPAADPMMI 275
           + KI+VKEAE+GD++  G AY+APG   M +  R G   + +         +P  D    
Sbjct: 239 LCKIEVKEAEDGDMLRPGVAYLAPGGKQMMLDGRPGAARLRIIDGGDRMNYKPCVDVTFG 298

Query: 276 TAAQVFGRRTVGVVMTGMGRDGAQGIVEIKKRGGITIAQDEKTSIIFGMPKAAIETGMVD 335
           +AA++FG + + +++TGMG DG +G   +K+ G    AQDE++ +++GMP+A  + G+  
Sbjct: 299 SAAKIFGDKVLSMILTGMGADGREGARMLKQAGATIWAQDEESCVVYGMPQAVAKAGIST 358

Query: 336 YVVPLEKIPETVV 348
             +PLE+I E ++
Sbjct: 359 EDLPLERIAERML 371


>gb|AAF32418.1| (AF069392) chemotaxis protein CheB [Vibrio parahaemolyticus]
           Length = 369
           
 Score =  243 bits (613), Expect = 3e-63
 Identities = 137/365 (37%), Positives = 213/365 (57%), Gaps = 28/365 (7%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           I+VLVVDDS+F R+ + +IINS+  LEV   A +G EA+E  +  +PDV+T+D+EMP M+
Sbjct: 3   IKVLVVDDSSFFRRRVSEIINSESRLEVIDVAVNGREAVEKAKALKPDVITMDIEMPVMD 62

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEI 127
           G+ A+R IM   P P++M S+LT +GA+AT+ AL+ GA+DF+PK    I+ N    +DE 
Sbjct: 63  GITAVREIMAASPTPILMFSSLTHDGAKATLDALDAGALDFLPKKFEDIARN----RDEA 118

Query: 128 IAKIKEAA-KVPRRFLELRRIRLLRVQKAKKVKP----------SVPARIAV-------- 168
           ++ +++   ++  +   +RR            +P          S PAR A         
Sbjct: 119 VSLLQQRVIQIASKRAFMRRPVARPAAATSAARPLASRTAAPAASAPARPAATKFRASGK 178

Query: 169 -----AIAASTGGPQSLLKIFPKFPENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKE 223
                AI  STGGP +L KI  + P N    I+L+QHMP  FT +FA RL+++ KI VKE
Sbjct: 179 KYQLTAIGTSTGGPVALQKILTRLPMNYPHPIVLIQHMPATFTAAFASRLNTLCKIQVKE 238

Query: 224 AEEGDVVEEGKAYVAPGDYHMEVTLRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGR 283
           A++GDV++ G AY+APG   M +  R G   + +         +P  D    +AA+V+G 
Sbjct: 239 AQDGDVLQAGVAYLAPGGKQMMIDGRAGAARLRIIDGGDRMNYKPCVDVTFGSAAKVYGD 298

Query: 284 RTVGVVMTGMGRDGAQGIVEIKKRGGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKI 343
           + + +V+TGMG DG +G   +K  G    AQDE++ +++GMP+A  + G+    +PL++I
Sbjct: 299 KVLSMVLTGMGADGREGARMLKSAGSTIWAQDEESCVVYGMPQAVAKAGISSEDLPLDRI 358

Query: 344 PETVV 348
            E ++
Sbjct: 359 AERMM 363


>sp|O52262|CHEB_PSEPU PROTEIN-GLUTAMATE METHYLESTERASE >gi|2853601|gb|AAC08065.1|
           (AF031898) CheB [Pseudomonas putida]
           Length = 374
           
 Score =  242 bits (610), Expect = 7e-63
 Identities = 135/373 (36%), Positives = 212/373 (56%), Gaps = 33/373 (8%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           ++VLVVDDS F R+ + +I+++DP ++V G A +G EAI+     +PDV+T+D EMP M+
Sbjct: 3   VKVLVVDDSGFFRRRVSEILSADPTIQVVGTATNGKEAIDQALALKPDVITMDYEMPMMD 62

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEI 127
           G+ A+R IM++ P PV+M S+LT EGA  T+ AL+ GA+D++PK    IS N  ++K  +
Sbjct: 63  GITAVRHIMQRCPTPVLMFSSLTHEGARVTLDALDAGAVDYLPKNFEDISRNPDKVKQML 122

Query: 128 IAKIKEAAKVPRRFLELRRIRLLRVQ-------------KAKKVKPSVPARIA------- 167
             K+   ++  RR     R   +                     +P+  AR A       
Sbjct: 123 CEKVHTISRSNRRLGSYARPAPVAAPVPASSPAPASSFASPAPARPAATARAAAPAASHS 182

Query: 168 ----------VAIAASTGGPQSLLKIFPKFPENLKAGILLVQHMPPGFTRSFAKRLDSVS 217
                     VAI  STGGP +L ++  + P N  A I+L+QHMP  FT++FA+RLD + 
Sbjct: 183 PAPKRKPYKLVAIGTSTGGPVALQRVLTQLPANFPAPIVLIQHMPAAFTKAFAERLDKLC 242

Query: 218 KIDVKEAEEGDVVEEGKAYVAPGDYHMEVTLRGGKPVITLNKKPKMHGVRPAADPMMITA 277
           +I+VKEAE+GD++  G A +APG   M +  RG   ++  +++      +P  D    +A
Sbjct: 243 RINVKEAEDGDMLRPGLALLAPGGKQMMIDGRGTVKILPGDER---LNYKPCVDITFGSA 299

Query: 278 AQVFGRRTVGVVMTGMGRDGAQGIVEIKKRGGITIAQDEKTSIIFGMPKAAIETGMVDYV 337
           A+ +G + + VV+TGMG DG +G   +K+ G    AQDE + +I+GMP A ++  + D V
Sbjct: 300 AKSYGDKVLSVVLTGMGADGREGARLLKQGGSTVWAQDEASCVIYGMPMAIVKANLADAV 359

Query: 338 VPLEKIPETVVRA 350
             L+ I + +V A
Sbjct: 360 YSLDDIGKHLVEA 372


>sp|O87125|CHEB_PSEAE PROTEIN-GLUTAMATE METHYLESTERASE >gi|11262675|pir||T46615
           chemotaxis protein cheB [imported] - Pseudomonas
           aeruginosa >gi|3721571|dbj|BAA33550.1| (AB012767) CheB
           [Pseudomonas aeruginosa]
           Length = 368
           
 Score =  241 bits (608), Expect = 1e-62
 Identities = 137/369 (37%), Positives = 213/369 (57%), Gaps = 27/369 (7%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           ++VLVVDDS F R+ + +I+++D +++V G A +G EAIE     RPDV+T+D EMP M+
Sbjct: 3   VKVLVVDDSGFFRRRVSEILSADGQIQVVGTATNGREAIEQALALRPDVITMDYEMPLMD 62

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEI 127
           G+ A+R IM++ P PV+M S+LT EGA  T+ AL+ GA+D++PK    IS N  +++  +
Sbjct: 63  GITAVRNIMQRCPTPVLMFSSLTHEGARVTLDALDAGAVDYLPKNFEDISRNPDKVRQLL 122

Query: 128 IAKIKEAAKVPRRFLELRRI-----------------RLLRVQKAKKVKP----SVPARI 166
             K+   A+  RR + L  +                    RV       P    + P R 
Sbjct: 123 CEKVLTIARSNRRSISLPPLPSATSSSHAPASSSSVGASARVGAGASPAPASTSAAPKRK 182

Query: 167 A---VAIAASTGGPQSLLKIFPKFPENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKE 223
           A   VAI  STGGP +L ++  + P N  A ++L+QHMP  FT++FA+RLD + +I+VKE
Sbjct: 183 AYRLVAIGTSTGGPVALQRVLTQLPANFPAPLVLIQHMPAAFTKAFAERLDKLCRINVKE 242

Query: 224 AEEGDVVEEGKAYVAPGDYHMEVTLRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGR 283
           AE+GD++  G A +APG   M V  RG   ++  +++      +P  D    +AA+ +  
Sbjct: 243 AEDGDILRPGLALLAPGGKQMMVDGRGTVRILPGDER---LNYKPCVDVTFGSAAKAYND 299

Query: 284 RTVGVVMTGMGRDGAQGIVEIKKRGGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKI 343
           + + VV+TGMG DG +G   +K+ G    AQDE + +I+GMP A ++  + D V  L+ I
Sbjct: 300 KVLAVVLTGMGADGREGARLLKQGGSQVWAQDEASCVIYGMPMAVVKANLADAVYGLDDI 359

Query: 344 PETVVRAVE 352
              +V A +
Sbjct: 360 GRHLVEACQ 368


>pir||G83463 probable methyltransferase PA1459 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9947411|gb|AAG04848.1|AE004575_7 (AE004575) probable
           methyltransferase [Pseudomonas aeruginosa]
           Length = 368
           
 Score =  239 bits (604), Expect = 3e-62
 Identities = 136/369 (36%), Positives = 212/369 (56%), Gaps = 27/369 (7%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           ++VLVVDDS F R+ + +I+++D +++V G   +G EAIE     RPDV+T+D EMP M+
Sbjct: 3   VKVLVVDDSGFFRRRVSEILSADGQIQVVGTGTNGREAIEQALALRPDVITMDYEMPLMD 62

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEI 127
           G+ A+R IM++ P PV+M S+LT EGA  T+ AL+ GA+D++PK    IS N  +++  +
Sbjct: 63  GITAVRNIMQRCPTPVLMFSSLTHEGARVTLDALDAGAVDYLPKNFEDISRNPDKVRQLL 122

Query: 128 IAKIKEAAKVPRRFLELRRI-----------------RLLRVQKAKKVKP----SVPARI 166
             K+   A+  RR + L  +                    RV       P    + P R 
Sbjct: 123 CEKVLTIARSNRRSISLPPLPSATSSSHAPASSSSVGASARVGAGASPAPASTSAAPKRK 182

Query: 167 A---VAIAASTGGPQSLLKIFPKFPENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKE 223
           A   VAI  STGGP +L ++  + P N  A ++L+QHMP  FT++FA+RLD + +I+VKE
Sbjct: 183 AYRLVAIGTSTGGPVALQRVLTQLPANFPAPLVLIQHMPAAFTKAFAERLDKLCRINVKE 242

Query: 224 AEEGDVVEEGKAYVAPGDYHMEVTLRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGR 283
           AE+GD++  G A +APG   M V  RG   ++  +++      +P  D    +AA+ +  
Sbjct: 243 AEDGDILRPGLALLAPGGKQMMVDGRGTVRILPGDER---LNYKPCVDVTFGSAAKAYND 299

Query: 284 RTVGVVMTGMGRDGAQGIVEIKKRGGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKI 343
           + + VV+TGMG DG +G   +K+ G    AQDE + +I+GMP A ++  + D V  L+ I
Sbjct: 300 KVLAVVLTGMGADGREGARLLKQGGSQVWAQDEASCVIYGMPMAVVKANLADAVYGLDDI 359

Query: 344 PETVVRAVE 352
              +V A +
Sbjct: 360 GRHLVEACQ 368


>gb|AAF67048.1|AF183382_8 (AF183382) methylesterase CheB [Pseudomonas putida]
           Length = 374
           
 Score =  238 bits (601), Expect = 8e-62
 Identities = 134/373 (35%), Positives = 210/373 (55%), Gaps = 33/373 (8%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           ++VLVVDDS F R+ + +I+++DP ++V G A +G EAI+     +PDV+T+D EMP M+
Sbjct: 3   VKVLVVDDSGFFRRRVSEILSADPTIQVVGTATNGKEAIDQALALKPDVITMDYEMPMMD 62

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEI 127
           G+ A+R IM++ P PV+M S+LT EGA  T+ AL+ GA+D++PK    IS N  ++K  +
Sbjct: 63  GITAVRHIMQRCPTPVLMFSSLTHEGARVTLDALDAGAVDYLPKNFEDISRNPDKVKQML 122

Query: 128 IAKIKEAAKVPRRF-------LELRRIRLLRVQKAKKVKPSVPARIA------------- 167
             K+   ++  RR           R +       A       PAR A             
Sbjct: 123 CEKVHTISRSNRRLGSYALAGAGRRPVPASSPAPASSFASPAPARPAATARAAAPAASHS 182

Query: 168 ----------VAIAASTGGPQSLLKIFPKFPENLKAGILLVQHMPPGFTRSFAKRLDSVS 217
                     + I  STGGP +L ++  + P N  A I+L+QHMP  FT++FA+RLD + 
Sbjct: 183 PAPKRKPYKLLRIGTSTGGPVALQRVLTQLPANFPAPIVLIQHMPAAFTKAFAERLDKLC 242

Query: 218 KIDVKEAEEGDVVEEGKAYVAPGDYHMEVTLRGGKPVITLNKKPKMHGVRPAADPMMITA 277
           +I+VKEAE+GD++  G A +APG   M +  RG   ++  +++      +P  D    +A
Sbjct: 243 RINVKEAEDGDMLRPGLALLAPGGKQMMIDGRGTVKILPGDER---LNYKPCVDITFGSA 299

Query: 278 AQVFGRRTVGVVMTGMGRDGAQGIVEIKKRGGITIAQDEKTSIIFGMPKAAIETGMVDYV 337
           A+ +G + + VV+TGMG DG +G   +K+ G    AQDE + +I+GMP A ++  + D V
Sbjct: 300 AKSYGDKVLSVVLTGMGADGREGARLLKQGGSTVWAQDEASCVIYGMPMAIVKANLADAV 359

Query: 338 VPLEKIPETVVRA 350
             L+ I + +V A
Sbjct: 360 YSLDDIGKHLVEA 372


>sp|O83639|CHEB_TREPA PROTEIN-GLUTAMATE METHYLESTERASE >gi|7435068|pir||E71300 probable
           protein-glutamate methylesterase (cheB) - syphilis
           spirochete >gi|3322930|gb|AAC65606.1| (AE001238)
           protein-glutamate methylesterase (cheB) [Treponema
           pallidum]
           Length = 403
           
 Score =  235 bits (594), Expect = 5e-61
 Identities = 140/392 (35%), Positives = 208/392 (52%), Gaps = 53/392 (13%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           I VL+VDDSA MRKV+  +I   P L + G+A +G  A++M+++ +PDV+ LD+EMP MN
Sbjct: 7   IAVLIVDDSALMRKVIGKVIEGAPGLSIAGKAMNGRFALDMLERVQPDVILLDLEMPHMN 66

Query: 68  GLDALRVIMK-KYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDE 126
           GL  L    + +  +PVI++S++ +EGA  T++ LE GA DF+ KP  S S ++R +  +
Sbjct: 67  GLQFLEQRKRLRIDIPVIILSSIAKEGARVTMQCLELGASDFVTKPFGSESAHLRTVSRK 126

Query: 127 IIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPS------------------------- 161
           I+  +       RR+  LRR R          +P+                         
Sbjct: 127 IVDYVTAYG---RRYKLLRRTRRCLAMDTPVERPAGEEDLNCLDTQERASLPSVCARAPA 183

Query: 162 -------------------VPARIA-----VAIAASTGGPQSLLKIFPKFPENLKAGILL 197
                              VP R +     +AI  STGGP +L  IF +   +L   +++
Sbjct: 184 RDRASYTITPTEGARQTRIVPLRESGALQIIAIGVSTGGPSALRHIFAQLDADLPQPVVV 243

Query: 198 VQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPGDYHMEVTLRGGKPVITL 257
           VQHMP GFTR FA  L+ V  ++VKEA+EGD+V  G+  +APGD H+ V  R    V  +
Sbjct: 244 VQHMPAGFTREFAYSLNQVCALEVKEAQEGDLVRRGRVLIAPGDRHLTVERRSLATVAHI 303

Query: 258 NKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQGIVEIKKRGGITIAQDEK 317
           N     +G RP+ D +  + A+ F  R +G++MTGMGRDGA  +  +   G  TIAQD  
Sbjct: 304 NSDEPENGHRPSVDVLFESVARHFENRALGILMTGMGRDGAAQLARLYTEGSRTIAQDAD 363

Query: 318 TSIIFGMPKAAIETGMVDYVVPLEKIPETVVR 349
           + I++GMP+ A E G V   V L+ +  T+ R
Sbjct: 364 SCIVYGMPRVACELGAVGEQVSLDDMAATINR 395


>sp|P72253|CHEB_RHOCE PROTEIN-GLUTAMATE METHYLESTERASE >gi|1621288|gb|AAB71332.1|
           (U64519) CheB [Rhodospirillum centenum (Rhodocista
           centenaria)]
           Length = 394
           
 Score =  216 bits (545), Expect = 3e-55
 Identities = 126/362 (34%), Positives = 195/362 (53%), Gaps = 28/362 (7%)

Query: 9   RVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMNG 68
           RV+VVDDSA +R ++   + SDPE++V     +G  AI  + +   DV+ LD+EMP ++G
Sbjct: 21  RVMVVDDSAVIRGLITRALESDPEIKVVASVANGQMAINTLSRQPIDVIVLDIEMPVLDG 80

Query: 69  LDALRVIMKKYP-VPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRE-LKDE 126
           L AL  +++  P V ++M S LT +GA+ +++AL  GA D+IPKPSS+  +   +  K E
Sbjct: 81  LSALPHLLQADPNVKIVMASTLTAKGADISLRALRAGAADYIPKPSSTRELTGADTFKRE 140

Query: 127 IIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPS----VPARI---------------- 166
           +  K+K      RR    R             +P+    +P+ +                
Sbjct: 141 LTEKVKALGAAARRSGPRREGTAAARPPGAAAQPTSGYTLPSPVRAKPETGPLTVRPLPP 200

Query: 167 -----AVAIAASTGGPQSLLKIFPKFPENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDV 221
                 +AI +STGGPQ+L ++           IL+ QHMP  FT   A  +     I  
Sbjct: 201 DGRPDVIAIGSSTGGPQALFEVLGHL-RGATQPILITQHMPATFTTILADHITRQCGIQC 259

Query: 222 KEAEEGDVVEEGKAYVAPGDYHMEVTLRGGKPVITLNKKPKMHGVRPAADPMMITAAQVF 281
            EA++G+ +  G+AYVAPGD+H  V  R G P + L K    +  RPA DPM+ +  + +
Sbjct: 260 AEAKDGEPIVGGRAYVAPGDFHFLVVNRNGVPTVQLTKDAPENFCRPAVDPMLRSIVRQW 319

Query: 282 GRRTVGVVMTGMGRDGAQGIVEIKKRGGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLE 341
           GRR + V++TGMG DG +G   + + GG+ I QDE TS+++GMP A    G+   ++PL+
Sbjct: 320 GRRVLSVILTGMGHDGQKGCESVVQAGGVVIGQDEATSVVWGMPGAVATAGLCSAILPLK 379

Query: 342 KI 343
           +I
Sbjct: 380 EI 381


>sp|O33558|CHEB_RHOSH PROTEIN-GLUTAMATE METHYLESTERASE >gi|11262673|pir||T45021
           protein-glutamate methylesterase (EC 3.1.1.61) cheB
           [imported] - Rhodobacter sphaeroides
           >gi|2293004|emb|CAA04433.1| (AJ000977) methylesterase
           [Rhodobacter sphaeroides]
           Length = 369
           
 Score =  215 bits (541), Expect = 8e-55
 Identities = 129/348 (37%), Positives = 199/348 (57%), Gaps = 9/348 (2%)

Query: 9   RVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMNG 68
           RVL+VDDSA  R + K I+ SDP L+V     D   A   ++   PDV+ LD+E+P M+G
Sbjct: 11  RVLIVDDSAAARAMFKVIVESDPALQVMAAVPDAFAAARAMRTELPDVILLDLELPSMDG 70

Query: 69  LDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEII 128
           L  LR IM+++P+PV++ S+    G EA + ALE GA + I KP++   +  +E    I 
Sbjct: 71  LTFLRKIMQQHPIPVVVCSSHVGAGTEAMVSALELGAREVISKPAARNDLERQEASIRIC 130

Query: 129 AKIKEAAKVPRRFLELRRIRLLRVQK--AKKVKPSVPAR------IAVAIAASTGGPQSL 180
             I+ A +  RR  +     L    K  A ++ P+ P R        V I ASTGG ++L
Sbjct: 131 DAIRAATETTRRRSQPEPRPLAPGPKLTADEILPARPPRPVPETMPVVCIGASTGGTEAL 190

Query: 181 LKIFPKFPENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPG 240
             +    P +    I++VQHMP GFT +FA+RLDS+  I+V EAE+   V  G+A +A G
Sbjct: 191 RDVLTALPASAPP-IVIVQHMPRGFTAAFARRLDSLCAIEVLEAEDEMQVMPGRAIIAQG 249

Query: 241 DYHMEVTLRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQG 300
           D H+ +  R     +++     +   RP+ D +  +AAQ  G   +GV+MTGMG DGA+ 
Sbjct: 250 DRHLLLRRRNQGYRVSVLDGAYVCRHRPSVDVLFRSAAQEAGGNALGVIMTGMGDDGARC 309

Query: 301 IVEIKKRGGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKIPETVV 348
           + E++  G  TIAQ+E++ +++GMP+ A+  G V  V PL+++   ++
Sbjct: 310 MAEMRAAGAETIAQNEESCVVYGMPREAVAHGGVGKVEPLDRLAARIM 357


>pir||A82206 protein-glutamate methylesterase CheB VC1401 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9655896|gb|AAF94558.1| (AE004218) protein-glutamate
           methylesterase CheB [Vibrio cholerae]
           Length = 358
           
 Score =  200 bits (503), Expect = 2e-50
 Identities = 117/327 (35%), Positives = 186/327 (56%), Gaps = 6/327 (1%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           +++LVVDDSA MR  + DI+ + P  E+   ARDG++AI+ V K +PDV+TLD+ MP M+
Sbjct: 1   MKILVVDDSALMRTTISDILQNIPNAEI-KTARDGMDAIDKVMKWQPDVMTLDINMPNMD 59

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEI 127
           GL  L  IM + P+P++M+S+LT EGA  T++AL  GA+DF+ KP  +I   ++E+   I
Sbjct: 60  GLTCLTQIMVERPLPIVMLSSLTHEGAITTLEALYLGAVDFVAKPGGTICGRLQEVAPLI 119

Query: 128 IAKIKEAAKVPRRF---LELRRIRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSLLKIF 184
             K++ AAK+  +    L +    +    K+  V+ +   ++A+ +  STGGP ++  I 
Sbjct: 120 REKVRAAAKMRVKVHTQLSVSPAEVEHKHKSPVVENNEDHQLAI-MGVSTGGPGTVETIL 178

Query: 185 PKFPENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPGDYHM 244
              P +    I++ QHMP  FT +FA+RL+   +  VKE     V+E G  YV  GD   
Sbjct: 179 RHLPADFSLPIIVNQHMPESFTAAFAQRLNRHLQQPVKEINRALVLEAGTVYVCKGDRDC 238

Query: 245 EVTLRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGR-RTVGVVMTGMGRDGAQGIVE 303
            VTLR GK               P+   ++ +A +  G    + V++TGMG DGA  + +
Sbjct: 239 IVTLRDGKLAAMPTPNDSHFSWHPSVSKLVASAIRTCGEDNLLCVMLTGMGDDGATEMAQ 298

Query: 304 IKKRGGITIAQDEKTSIIFGMPKAAIE 330
           + +  GI  AQ+  T ++  MP+A ++
Sbjct: 299 VAQGNGIVFAQEPTTCVVPSMPEALLK 325


>sp|O51376|Y415_BORBU PROBABLE PROTEIN-GLUTAMATE METHYLESTERASE BB0415
           >gi|7435071|pir||F70151 protein-glutamate methylesterase
           (cheB-1) homolog - Lyme disease spirochete
           >gi|2688322|gb|AAC66789.1| (AE001146) protein-glutamate
           methylesterase (cheB-1) [Borrelia burgdorferi]
           Length = 375
           
 Score =  178 bits (448), Expect = 7e-44
 Identities = 113/362 (31%), Positives = 196/362 (53%), Gaps = 32/362 (8%)

Query: 7   KIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRM 66
           KI VL+++  A  RK++ D+INS P+L+V   A +   A   ++K +P+V+ +++E   +
Sbjct: 4   KISVLIIEYFAVKRKLISDLINSSPKLQVIATASNSKFATNKLKKHKPEVILMNLEENNI 63

Query: 67  NG---LDALRVIMKKYPVPVI-----MISALTQEGAEATI------------------KA 100
                L+    + K  P+ V      +I+    +GA+  I                    
Sbjct: 64  KDILFLEEKNSLNKTIPIVVTSSNQNLINIAASKGADDLILVSKNKKSHEIKKEQIINSL 123

Query: 101 LEYGAIDFIPKPSSSISINMREL-KDEIIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVK 159
           L YG+I    K + +  +  +   +   I   K       +  E  + + L  ++ KK+K
Sbjct: 124 LAYGSISIKNKIACNKDMKTKNYERANFILNHKNDISSLNQLEEHAKEKTLNEKEIKKLK 183

Query: 160 PSVPARIAVAIAASTGGPQSLLKIFPKFPENLKAGILLVQHMPPGFTRSFAKRLDSVSKI 219
             +     +AI  S GGP +L  I P+ PE+    I++VQHMP GFT  FAK L+++ KI
Sbjct: 184 --LRKFDIIAIGVSAGGPVALKSILPEIPESFPP-IIIVQHMPKGFTEEFAKNLNNLCKI 240

Query: 220 DVKEAEEGDVVEEGKAYVAPGDYHMEV-TLRGGKPVITLNKKPKMHGVRPAADPMMITAA 278
            VKE    +++++G AY++ G YH ++  + G   + TL+ K  ++G +P+   +  + A
Sbjct: 241 SVKETTNNEILKQGYAYISSGGYHTKIKKIDGNYQIKTLDGK-HINGHKPSIGVLFQSIA 299

Query: 279 QVFGRRTVGVVMTGMGRDGAQGIVEIKKRGGITIAQDEKTSIIFGMPKAAIETGMVDYVV 338
           ++   + + ++MTGMG DG++ I +IKK GG+TIAQD+++S++FGMPK AI+   +DY+V
Sbjct: 300 EIAKDKAIAIIMTGMGNDGSREIGDIKKAGGLTIAQDKESSMVFGMPKIAIKENNIDYIV 359

Query: 339 PL 340
           PL
Sbjct: 360 PL 361


>sp|P31758|FRZG_MYXXA PROTEIN-GLUTAMATE METHYLESTERASE FRZG >gi|94529|pir||A36707
           protein-glutamate methylesterase homolog - Myxococcus
           xanthus >gi|150093|gb|AAA25397.1| (M35200) FrzG protein
           [Myxococcus xanthus]
           Length = 334
           
 Score =  169 bits (425), Expect = 3e-41
 Identities = 105/311 (33%), Positives = 174/311 (55%), Gaps = 18/311 (5%)

Query: 45  AIEMVQKCRPDVVTLDVEMPRMNGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYG 104
           A+  VQ+  PDVV +D+    ++ L A+  +M + PVPV+ +      G EA  +A+  G
Sbjct: 39  ALVAVQRHFPDVVLVDLSA--LDALPAIEHVMVERPVPVLALHPGVLSGQEA-FQAMVAG 95

Query: 105 AIDFIPKPSSSISINMRELKDEII--AKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSV 162
           A+D + +P++        +  +++  A++K   +V  R            Q A++ KP  
Sbjct: 96  ALDVLERPANPGPEFWTHVSRKLVLLAQVKAVRQVQTR---------PPPQAAREAKPPP 146

Query: 163 PARIAVAIAASTGGPQSLLKIFPKFPENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVK 222
           P  + VAIAAS GGP+++ ++    P    A I   QH+  GFT   A  L + + + V 
Sbjct: 147 PYPL-VAIAASLGGPKAVAQVLRMIPRAFPAPIAYCQHISDGFTEGLAHWLSNETALRVL 205

Query: 223 EAEEGDVVEEGKAYVAPGDYHMEVTLRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFG 282
           EAE   ++  G  Y+AP   H+ V   G    + L+  P + G RP+ D ++ +A + FG
Sbjct: 206 EAEHDVLMAPGTVYIAPSGSHLLVRPEGR---LELDAGPALRGFRPSCDMLLTSAGESFG 262

Query: 283 RRTVGVVMTGMGRDGAQGIVEIKKRGGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEK 342
            R +GV++TGMGRDGA+G+ EI++RGG TIAQDE +S+++GMP+ A+  G    V+PL +
Sbjct: 263 PRCIGVILTGMGRDGARGLKEIRERGGRTIAQDEASSVVWGMPREAVLMGAAHEVLPLSR 322

Query: 343 IPETVVRAVEM 353
           I   +++ V++
Sbjct: 323 IGAALMQWVDV 333


>pir||F83183 probable methylesterase PA3703 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9949867|gb|AAG07090.1|AE004789_10
           (AE004789) probable methylesterase [Pseudomonas
           aeruginosa]
           Length = 335
           
 Score =  166 bits (415), Expect = 5e-40
 Identities = 106/336 (31%), Positives = 180/336 (53%), Gaps = 10/336 (2%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           +R+ +V+D     + L+  +  +P+ ++   A +G EA+       PDVV +D+ MP M+
Sbjct: 1   MRIGIVNDMPLAVEALRRALAFEPQHQIVWVASNGAEAVTQCAADTPDVVLMDLLMPVMD 60

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEI 127
           G++A R IM + P  +++++   ++      +A+ YGA+D +  P+  I  N +     +
Sbjct: 61  GVEATRRIMAESPCAIVIVTVDIEQNVHRVFEAMGYGALDAVNTPALGIG-NPQTAAAPL 119

Query: 128 IAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAIAASTGGPQSLLKIFPKF 187
           + KI+        +L  +R    +VQ           R+ VAI AS GGP SL  +  + 
Sbjct: 120 LRKIQNVG-----WLIGQRDNRGKVQVVPPKAGGARQRL-VAIGASAGGPASLAVLLKQL 173

Query: 188 PENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPGDYHMEVT 247
           P +  A ++LVQH+   F    A+ L S SK+ V+ A +G+    G+  +A  + H+ + 
Sbjct: 174 PASFNAAVVLVQHVDEVFAAGMAEWLASESKLPVRLARDGEPPIPGQILLAGTNNHIRL- 232

Query: 248 LRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQGIVEIKKR 307
           LR G  V T   +P+    RP+ D    + A  +    VGV++TGMGRDGAQG+ ++++R
Sbjct: 233 LRNGSLVYTA--EPRSFVYRPSIDVFFESVANYWRGDAVGVLLTGMGRDGAQGLKQMRER 290

Query: 308 GGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKI 343
           G +TIAQD+ +  ++GMPKAA        ++ LEKI
Sbjct: 291 GFLTIAQDQASCAVYGMPKAAAAIDAAVQILSLEKI 326


>sp|Q45047|CHEB_BORBU PROTEIN-GLUTAMATE METHYLESTERASE >gi|7435067|pir||G70170
           protein-glutamate methylesterase (cheB-2) homolog - Lyme
           disease spirochete >gi|2688489|gb|AAC66934.1| (AE001158)
           protein-glutamate methylesterase (cheB-2) [Borrelia
           burgdorferi]
           Length = 385
           
 Score =  164 bits (410), Expect = 2e-39
 Identities = 111/384 (28%), Positives = 196/384 (50%), Gaps = 43/384 (11%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           +++LV+D    +++V     + D ++E+     + +  I +  +  PD+V +D    R N
Sbjct: 1   MKILVIDIQGLIKQVFVRAFSKDNDVEILNAGFNSLNLINVFLQKFPDLVIIDENTARSN 60

Query: 68  GLDALRVIMKKYPVPVIMISA-----------LTQEGAEATIKALEYG-AID-FIPKPSS 114
             ++L  ++    +PV+ I+             ++E  +  I  L +   +D F  K  +
Sbjct: 61  FGNSLNNVLNNISLPVVFIAQNEMLPNFGCLEQSKEKVKLIINKLNFKLTVDLFRSKYLA 120

Query: 115 SISINMREL-KDEIIAKIK----------EAAKVPRRFLELRRIRLLR-------VQKAK 156
            I + ++ L K+++I+  +            +KV  R   L    + +       +  A 
Sbjct: 121 LIKLELKNLGKNKLISSFEVKRIQAPDFSSNSKVELRENNLNDSSIRKSYRVSDVINFAP 180

Query: 157 KVKPSVPARIA-----------VAIAASTGGPQSLLKIFPKFPENLKAGILLVQHMPPGF 205
           K  P V  +             + + +STGG ++L +IF +  +     I++VQHMP GF
Sbjct: 181 KNDPDVIIKYQGLINKHKTGKIIVVGSSTGGTEAL-RIFLRSFKKDSPPIIIVQHMPGGF 239

Query: 206 TRSFAKRLDSVSKIDVKEAEEGDVVEEGKAYVAPGDYHMEVTLRGGKPVITLNKKPKMHG 265
           T+SFAK L++   ID+KEAE+GD++  G   +A G YH+ V    G   + L   P +  
Sbjct: 240 TKSFAKNLNNEFNIDIKEAEDGDILRPGLVIIANGSYHLIVKYSSGNYFVNLLDGPLVSR 299

Query: 266 VRPAADPMMITAAQVFGRRTVGVVMTGMGRDGAQGIVEIKKRGGITIAQDEKTSIIFGMP 325
            +P+ + +  +AA   G   +GV++TGMG DGA  ++E+KK G  TIAQD++TS++FGMP
Sbjct: 300 HKPSVNVLFRSAAMYAGSNAIGVILTGMGDDGAVCMLEMKKNGAYTIAQDQETSVVFGMP 359

Query: 326 KAAIETGMVDYVVPLEKIPETVVR 349
             AI+ G VD ++PL +I + V+R
Sbjct: 360 MEAIKIGAVDKILPLSEIADHVLR 383


>pdb|1CHD|   Cheb Methylesterase Domain
           Length = 203
           
 Score =  159 bits (398), Expect = 5e-38
 Identities = 80/195 (41%), Positives = 124/195 (63%), Gaps = 1/195 (0%)

Query: 157 KVKPSVPARIAVAIAASTGGPQSLLKIFPKFPENLKAGILLVQHMPPGFTRSFAKRLDSV 216
           K  P + +   +AI ASTGG +++  +    P +  A +++ QHMPPGFTRSFA+RL+ +
Sbjct: 2   KAGPLLSSEKLIAIGASTGGTEAIRHVLQPLPLSSPA-VIITQHMPPGFTRSFAERLNKL 60

Query: 217 SKIDVKEAEEGDVVEEGKAYVAPGDYHMEVTLRGGKPVITLNKKPKMHGVRPAADPMMIT 276
            +I VKEAE+G+ V  G AY+APGD HME+   G    I ++  P ++  RP+ D +  +
Sbjct: 61  CQISVKEAEDGERVLPGHAYIAPGDKHMELARSGANYQIKIHDGPPVNRHRPSVDVLFHS 120

Query: 277 AAQVFGRRTVGVVMTGMGRDGAQGIVEIKKRGGITIAQDEKTSIIFGMPKAAIETGMVDY 336
            A+  GR  VGV++TGMG DGA G++ + + G  TIAQ+E + ++FGMP+ AI  G V  
Sbjct: 121 VAKHAGRNAVGVILTGMGNDGAAGMLAMYQAGAWTIAQNEASCVVFGMPREAINMGGVSE 180

Query: 337 VVPLEKIPETVVRAV 351
           VV L ++ + ++  +
Sbjct: 181 VVDLSQVSQQMLAKI 195


>sp|Q56312|CHEY_THEMA CHEMOTAXIS PROTEIN CHEY >gi|7443033|pir||B72346 chemotaxis response
           regulator CheY - Thermotoga maritima  (strain MSB8)
           >gi|2781289|pdb|1TMY|  Chey From Thermotoga Maritima
           (Apo-I) >gi|2781153|pdb|3TMY|A Chain A, Chey From
           Thermotoga Maritima (Mn-Iii) >gi|2781154|pdb|3TMY|B
           Chain B, Chey From Thermotoga Maritima (Mn-Iii)
           >gi|2781128|pdb|2TMY|  Chey From Thermotoga Maritima
           (Apo-Ii) >gi|2781158|pdb|4TMY|A Chain A, Chey From
           Thermotoga Maritima (Mg-Iv) >gi|2781159|pdb|4TMY|B Chain
           B, Chey From Thermotoga Maritima (Mg-Iv)
           >gi|940149|gb|AAA96389.1| (U30501) CheY [Thermotoga
           maritima] >gi|4981223|gb|AAD35782.1|AE001741_15
           (AE001741) chemotaxis response regulator CheY
           [Thermotoga maritima]
           Length = 120
           
 Score = 96.3 bits (236), Expect = 5e-19
 Identities = 53/105 (50%), Positives = 74/105 (70%), Gaps = 4/105 (3%)

Query: 9   RVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMNG 68
           RVL+VDD+AFMR +LKDII      EV GEA +G EA+E  ++ +PD+VT+D+ MP MNG
Sbjct: 4   RVLIVDDAAFMRMMLKDIITK-AGYEVAGEATNGREAVEKYKELKPDIVTMDITMPEMNG 62

Query: 69  LDALRVIMKKYP-VPVIMISALTQEGAEATIKALEYGAIDFIPKP 112
           +DA++ IMK  P   +I+ SA+ Q+     I+A++ GA DFI KP
Sbjct: 63  IDAIKEIMKIDPNAKIIVCSAMGQQA--MVIEAIKAGAKDFIVKP 105


>emb|CAA53764.1| (X76170) cheY [Listeria monocytogenes]
           Length = 119
           
 Score = 95.2 bits (233), Expect = 1e-18
 Identities = 53/130 (40%), Positives = 84/130 (63%), Gaps = 13/130 (10%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           +++L+VDD+ FMR ++K+I+  D + EV  EA +G+EA++   + +PD+VTLD+ MP M+
Sbjct: 2   LKLLIVDDAMFMRTMIKNIVK-DSDFEVVAEAENGLEAVKKYDEVKPDIVTLDITMPEMD 60

Query: 68  GLDALRVIMKKYP-VPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDE 126
           GL+AL  IM K P   VIM SA+ Q+G    + A++ GA DFI KP  +         D 
Sbjct: 61  GLEALAQIMAKDPSAKVIMCSAMGQQG--MVVDAIKKGAKDFIVKPFQA---------DR 109

Query: 127 IIAKIKEAAK 136
           ++  +++AAK
Sbjct: 110 VLEALEKAAK 119


>gi|11498647 chemotaxis response regulator (cheY) [Archaeoglobus fulgidus]
           >gi|7443007|pir||B69380 chemotaxis response regulator
           (cheY) homolog - Archaeoglobus fulgidus
           >gi|2649557|gb|AAB90207.1| (AE001031) chemotaxis
           response regulator (cheY) [Archaeoglobus fulgidus]
           Length = 121
           
 Score = 87.4 bits (213), Expect = 2e-16
 Identities = 49/117 (41%), Positives = 80/117 (67%), Gaps = 5/117 (4%)

Query: 9   RVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMNG 68
           +VL+VDD+AFMRK+L++I+ S    ++ GEA +G +A+EM ++ +PD+VT+D+ MP MNG
Sbjct: 3   KVLIVDDTAFMRKLLRNILFSGG-FDIAGEAENGKQAVEMYKQLKPDIVTMDIVMPEMNG 61

Query: 69  LDALRVIMKKYP-VPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELK 124
           ++AL+ I K  P   V+M +A+ QE  +    A++ GA  +I KP  +  + + ELK
Sbjct: 62  IEALKAIKKIDPSAKVVMCTAVGQE--QMVKAAIKLGAKGYIVKPFQAPKV-IEELK 115


>gb|AAC27631.1| (AF076485) defective in fruiting DifD [Myxococcus xanthus]
           Length = 122
           
 Score = 86.6 bits (211), Expect = 4e-16
 Identities = 51/105 (48%), Positives = 70/105 (66%), Gaps = 4/105 (3%)

Query: 9   RVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMNG 68
           RVLVVDD+ FMR ++KDI  S    EV GEA +G+EA+E  ++ +PD+ T+D+ MP  +G
Sbjct: 4   RVLVVDDAIFMRNMIKDIFASGG-FEVVGEAANGLEAVEKYKELKPDLTTMDIVMPFKSG 62

Query: 69  LDALRVIMK-KYPVPVIMISALTQEGAEATIKALEYGAIDFIPKP 112
           ++A R I+K      VIM SAL QE     ++A+E GA DFI KP
Sbjct: 63  IEATREIIKADSSAVVIMCSALGQE--SLVMEAIEAGASDFIVKP 105


>pir||E71160 probable chemotaxis protein (cheY) - Pyrococcus horikoshii
           >gi|3256887|dbj|BAA29570.1| (AP000002) 120aa long
           hypothetical chemotaxis protein (cheY) [Pyrococcus
           horikoshii]
           Length = 120
           
 Score = 85.4 bits (208), Expect = 9e-16
 Identities = 50/105 (47%), Positives = 72/105 (67%), Gaps = 4/105 (3%)

Query: 9   RVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMNG 68
           RVLVVDD+AFMR +LK I+      EV GEA +G EA+E  ++ +PD+VT+D+ MP M+G
Sbjct: 3   RVLVVDDAAFMRMLLKKILTQAGH-EVVGEASNGKEAVEKYKQLKPDLVTMDIVMPEMDG 61

Query: 69  LDALRVIMKKYP-VPVIMISALTQEGAEATIKALEYGAIDFIPKP 112
           + A++ IMK  P   +IMI+A+ QE     ++AL+ GA  +I KP
Sbjct: 62  ITAVKEIMKIDPNAKIIMITAVGQEA--KVMEALKSGAKGYIVKP 104


>pir||F75002 chemotaxis response regulator (chey) PAB1330 - Pyrococcus abyssi
           (strain Orsay) >gi|5458974|emb|CAB50460.1| (AJ248288)
           chemotaxis response regulator (cheY) [Pyrococcus abyssi]
           Length = 120
           
 Score = 85.0 bits (207), Expect = 1e-15
 Identities = 49/105 (46%), Positives = 72/105 (67%), Gaps = 4/105 (3%)

Query: 9   RVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMNG 68
           R+LVVDD+AFMR +LK I+      EV GEA +G EA+E  ++ +PD+VT+D+ MP M+G
Sbjct: 3   RILVVDDAAFMRMLLKKILTQAGH-EVVGEASNGKEAVEKYKQLKPDLVTMDIVMPEMDG 61

Query: 69  LDALRVIMKKYP-VPVIMISALTQEGAEATIKALEYGAIDFIPKP 112
           + A++ IMK  P   +IMI+A+ QE     ++AL+ GA  +I KP
Sbjct: 62  ITAVKEIMKIDPNAKIIMITAVGQEA--KVMEALKSGAKGYIVKP 104


>dbj|BAB06687.1| (AP001517) two-component response regulator involved in modulation
           of flagellar [Bacillus halodurans]
           Length = 120
           
 Score = 83.9 bits (204), Expect = 3e-15
 Identities = 50/105 (47%), Positives = 71/105 (67%), Gaps = 6/105 (5%)

Query: 10  VLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMNGL 69
           VLVVDD+AFMR ++KDI+  + + EV GEA +G EA+++ ++  PD+VTLD+ MP  +G+
Sbjct: 4   VLVVDDAAFMRMMIKDILTKN-DFEVVGEAANGEEAVQLYKEHSPDLVTLDITMPEKDGI 62

Query: 70  DALRVIMKKY--PVPVIMISALTQEGAEATIKALEYGAIDFIPKP 112
            AL+ I K Y     VIM SA+ Q+     I A++ GA DFI KP
Sbjct: 63  QALKEI-KAYDADAKVIMCSAMGQQA--MVIDAIQSGAKDFIVKP 104


>dbj|BAB06163.1| (AP001515) two-component response regulator involved in modulation
           of flagellar [Bacillus halodurans]
           Length = 121
           
 Score = 81.5 bits (198), Expect = 1e-14
 Identities = 46/105 (43%), Positives = 69/105 (64%), Gaps = 4/105 (3%)

Query: 9   RVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMNG 68
           R+L+VDD++FMR ++KDI+  +   +V GEA DG +A+E  ++  PD+VT+D+ MP  +G
Sbjct: 4   RILIVDDASFMRMMIKDILTKNG-YDVVGEAHDGEQAVEKYKELSPDLVTMDITMPEKDG 62

Query: 69  LDALRVIMKKYP-VPVIMISALTQEGAEATIKALEYGAIDFIPKP 112
           + AL+ I    P   VIM SA+ Q+     I A++ GA DFI KP
Sbjct: 63  IAALKDIRAIDPNAKVIMCSAMGQQA--MVIDAIQAGAKDFIVKP 105


>sp|P45709|CCDB_BACSU CCDB PROTEIN >gi|1361404|pir||S57405 response regulator homolog
           yneI - Bacillus subtilis >gi|870926|emb|CAA61117.1|
           (X87845) response regulator [Bacillus subtilis]
           >gi|1405450|emb|CAA97595.1| (Z73234) YneI [Bacillus
           subtilis] >gi|2634178|emb|CAB13678.1| (Z99113) alternate
           gene name: yoxH~similar to two-component response
           regulator (CheY homolog) [Bacillus subtilis]
           Length = 120
           
 Score = 81.1 bits (197), Expect = 2e-14
 Identities = 47/105 (44%), Positives = 68/105 (64%), Gaps = 4/105 (3%)

Query: 9   RVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMNG 68
           RVLVVDD+ FMR  +++I+  +    + GEA DG +A ++ +K RPD+VT+D+ MP  NG
Sbjct: 3   RVLVVDDAKFMRVKIREILE-EANYIIAGEAADGEQAADLYKKLRPDLVTMDITMPVKNG 61

Query: 69  LDALRVIMKKYP-VPVIMISALTQEGAEATIKALEYGAIDFIPKP 112
           + ALR I+   P   VIM +A+ Q+      +A+E GA DFI KP
Sbjct: 62  IKALRDILTFDPKAKVIMCTAMRQQ--RIVTEAIELGAKDFIVKP 104


>emb|CAB99140.1| (AL390188) putative two-component system response regulator
           [Streptomyces coelicolor A3(2)]
           Length = 220
           
 Score = 81.1 bits (197), Expect = 2e-14
 Identities = 39/104 (37%), Positives = 64/104 (61%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           +RVL+VDD   +R  L+ ++ + P++EV GEA DG   + +V++ RPDVV +DV MP ++
Sbjct: 3   VRVLLVDDEPLVRAGLRAVLEAQPDIEVVGEAADGAAVVPLVRQVRPDVVAMDVRMPLLD 62

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPK 111
           G++A R +++    P  ++   T E  E   +AL  GA  F+ K
Sbjct: 63  GIEATRALLRTVADPPKILVVTTFENDEYVYEALRAGADGFLLK 106


>sp|P24072|CHEY_BACSU CHEMOTAXIS PROTEIN CHEY HOMOLOG >gi|98251|pir||A40874 chemotactic
           tumbling protein cheY - Bacillus subtilis
           >gi|142682|gb|AAA22311.1| (M59781) chemotactic response
           protein [Bacillus subtilis] >gi|2634005|emb|CAB13506.1|
           (Z99112) two-component response regulator [Bacillus
           subtilis]
           Length = 120
           
 Score = 80.0 bits (194), Expect = 4e-14
 Identities = 45/105 (42%), Positives = 69/105 (64%), Gaps = 4/105 (3%)

Query: 9   RVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMNG 68
           R+L+VDD+AFMR ++KDI+  +   EV  EA +G +A+E  ++  PD+VT+D+ MP M+G
Sbjct: 4   RILIVDDAAFMRMMIKDILVKNG-FEVVAEAENGAQAVEKYKEHSPDLVTMDITMPEMDG 62

Query: 69  LDALRVIMK-KYPVPVIMISALTQEGAEATIKALEYGAIDFIPKP 112
           + AL+ I +      +IM SA+ Q+     I A++ GA DFI KP
Sbjct: 63  ITALKEIKQIDAQARIIMCSAMGQQ--SMVIDAIQAGAKDFIVKP 105


>sp|P54662|DEGU_BACBR TRANSCRIPTIONAL REGULATORY PROTEIN DEGU >gi|2119837|pir||I39835
           transcription activator - Bacillus brevis
           >gi|710496|gb|AAC41439.1| (L15444) transcriptional
           activator protein [Brevibacillus brevis]
           Length = 236
           
 Score = 78.0 bits (189), Expect = 2e-13
 Identities = 34/105 (32%), Positives = 68/105 (64%), Gaps = 1/105 (0%)

Query: 7   KIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRM 66
           KI+++++DD    R+ +K I+  +PE EV  +  DG  A+E+V+K  PDV+ +D+ MP++
Sbjct: 9   KIQIVIIDDHQLFREGVKRILAMEPEFEVVADGEDGENAVELVEKYNPDVILMDINMPKV 68

Query: 67  NGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPK 111
           NG++A R ++++YP   +++ ++  + +  T   L+ GA  ++ K
Sbjct: 69  NGVEATRDLIQRYPDVKVLVLSIHDDESYVT-HVLKTGASGYLLK 112


>pir||T35758 probable response regulator - Streptomyces coelicolor
           >gi|5689906|emb|CAB52069.1| (AL109732) putative response
           regulator [Streptomyces coelicolor A3(2)]
           Length = 218
           
 Score = 78.0 bits (189), Expect = 2e-13
 Identities = 50/146 (34%), Positives = 85/146 (57%), Gaps = 18/146 (12%)

Query: 2   PLTGRKIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDV 61
           PLT    RV++ +D A +R  LK+++  +    V GEA DG EA+E+ ++ RPD+V LDV
Sbjct: 22  PLT---TRVVIAEDEALIRLDLKEMLEEEG-YSVVGEAGDGEEAVELAREHRPDLVILDV 77

Query: 62  EMPRMNGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMR 121
           +MP+M+G+ A   I ++   PV+M++A +Q   +   +A + GA+ ++ KP S       
Sbjct: 78  KMPKMDGISAAEKIAEESIAPVLMLTAFSQR--DLVERARDAGAMAYLVKPFS------- 128

Query: 122 ELKDEIIAKIKEAAKVPRRFLELRRI 147
             K +++  I+ A     RF EL+ +
Sbjct: 129 --KSDVVPAIEMAVS---RFTELKAL 149


>sp|P52931|SP0A_BACCI STAGE 0 SPORULATION PROTEIN A >gi|497953|gb|AAA18874.1| (U09973)
           Spo0A [Bacillus circulans subsp. circulans]
           Length = 210
           
 Score = 77.3 bits (187), Expect = 3e-13
 Identities = 45/109 (41%), Positives = 72/109 (65%), Gaps = 4/109 (3%)

Query: 6   RKIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPR 65
           +KI+V +VDD+  +  +L++ I++  ++EV G A +G E +E+V++  PDV+ LD+ MP 
Sbjct: 2   KKIKVCIVDDNRELVGLLEEYIDAQDDMEVIGVAHNGQECLELVEQLEPDVMVLDIIMPH 61

Query: 66  MNGLDAL-RVIMKKYPVP-VIMISALTQEGAEATIKALEYGAIDFIPKP 112
           ++GL  L R+     P+P VIM++A  QE  + T KA+E GA  FI KP
Sbjct: 62  IDGLAVLERMRQMNKPMPNVIMLTAFGQE--DVTKKAVELGASYFILKP 108


>pir||S60871 phosphorylation-activated transcription factor Spo0A - Bacillus
           circulans (fragment)
           Length = 211
           
 Score = 77.3 bits (187), Expect = 3e-13
 Identities = 45/109 (41%), Positives = 72/109 (65%), Gaps = 4/109 (3%)

Query: 6   RKIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPR 65
           +KI+V +VDD+  +  +L++ I++  ++EV G A +G E +E+V++  PDV+ LD+ MP 
Sbjct: 2   KKIKVCIVDDNRELVGLLEEYIDAQDDMEVIGVAHNGQECLELVEQLEPDVMVLDIIMPH 61

Query: 66  MNGLDAL-RVIMKKYPVP-VIMISALTQEGAEATIKALEYGAIDFIPKP 112
           ++GL  L R+     P+P VIM++A  QE  + T KA+E GA  FI KP
Sbjct: 62  IDGLAVLERMRQMNKPMPNVIMLTAFGQE--DVTKKAVELGASYFILKP 108


>sp|P52934|SP0A_BACST STAGE 0 SPORULATION PROTEIN A >gi|2654216|emb|CAA05307.1|
           (AJ002297) Spo0A protein [Bacillus stearothermophilus]
           Length = 259
           
 Score = 76.9 bits (186), Expect = 3e-13
 Identities = 45/136 (33%), Positives = 84/136 (61%), Gaps = 6/136 (4%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           I+V + DD+  +  +L + I+S P++EV G A +G + ++M+++ RPD++ LD+ MP ++
Sbjct: 3   IKVCIADDNRELVSLLDEYISSQPDMEVIGTAYNGQDCLQMLEEKRPDILLLDIIMPHLD 62

Query: 68  GLDALRVIMK--KYPVPVIMISALTQEGAEATIKALEYGAIDFIPKP--SSSISINMREL 123
           GL  L  I    ++   VIM++A  QE  + T KA+E GA  FI KP    +++ ++R++
Sbjct: 63  GLAVLERIRAGFEHQPNVIMLTAFGQE--DVTKKAVELGASYFILKPFDMENLAHHIRQV 120

Query: 124 KDEIIAKIKEAAKVPR 139
             +    +++AA  P+
Sbjct: 121 YGKTTPVVRKAAPAPQ 136


>gb|AAD16452.1| (AF102271) response-regulator [Streptomyces coelicolor A3(2)]
           >gi|8568799|emb|CAB94548.1| (AL359152) chitinase
           two-component response regulator [Streptomyces
           coelicolor A3(2)]
           Length = 213
           
 Score = 76.5 bits (185), Expect = 5e-13
 Identities = 40/104 (38%), Positives = 66/104 (63%), Gaps = 2/104 (1%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           IRVLV +D + +R  L  I+ S P++EV GEA DG +A+ + ++ RPD+V +DV+MPRM+
Sbjct: 2   IRVLVAEDQSAVRAGLVLILGSAPDIEVVGEAADGEQAVALARELRPDLVLMDVQMPRMD 61

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPK 111
           G+ A R+++ +    V++++    +  E    AL  GA  F+ K
Sbjct: 62  GVSATRIVVGEQLADVLVLTTFDLD--EYVFGALRAGAAGFLLK 103


>dbj|BAB07347.1| (AP001519) two-component response regulator involved in degradative
           enzyme [Bacillus halodurans]
           Length = 236
           
 Score = 75.7 bits (183), Expect = 8e-13
 Identities = 33/105 (31%), Positives = 67/105 (63%), Gaps = 1/105 (0%)

Query: 7   KIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRM 66
           KI+++++DD    R+ +K I+  +PE EV  +  DG  A+E+V+   PDV+ +D+ MP++
Sbjct: 9   KIQIVIIDDHQLFREGVKRILAMEPEFEVVADGEDGENAVELVETYNPDVILMDINMPKV 68

Query: 67  NGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPK 111
           NG++A R ++++YP   +++ ++  + +  T   L+ GA  ++ K
Sbjct: 69  NGVEATRDLIQRYPDVKVLVLSIHDDESYVT-HVLKTGASGYLLK 112


>sp|P55184|YXJL_BACSU HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN GALE-PEPT INTERGENIC
           REGION >gi|1429258|emb|CAA67717.1| (X99339) orf4;
           putative [Bacillus subtilis]
           Length = 218
           
 Score = 75.3 bits (182), Expect = 1e-12
 Identities = 42/130 (32%), Positives = 74/130 (56%), Gaps = 10/130 (7%)

Query: 7   KIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRM 66
           KIRV + DD   +R+  + +IN+  ++ V GEA DG + I + ++ +PDV+ +DV+MPR 
Sbjct: 5   KIRVALADDQPLVREAFRYVINAQTDMTVSGEAGDGHDIIALAKQTKPDVILMDVQMPRC 64

Query: 67  NGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDE 126
           +G++A + IM   P   I+I   T +  E   + +  GA+ ++ K +         L +E
Sbjct: 65  SGIEAAKDIMSALPNTKIVI-LTTFDTEEYVFEGIRAGAVGYLLKDT---------LPEE 114

Query: 127 IIAKIKEAAK 136
           +I  I+ AA+
Sbjct: 115 LIDAIRAAAR 124


>emb|CAA63989.1| (X94328) spo0a [Clostridium difficile]
           Length = 256
           
 Score = 74.9 bits (181), Expect = 1e-12
 Identities = 50/208 (24%), Positives = 111/208 (53%), Gaps = 9/208 (4%)

Query: 7   KIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRM 66
           KI++++ DD+    +VLK+ ++++ ++++ G A+DGIEA+++V+K +PD++ LDV MP +
Sbjct: 8   KIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGIEALDLVKKTQPDLLILDVIMPHL 67

Query: 67  NGLDALRVI----MKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRE 122
           +GL  +  +    + K P  +I++SA+ Q+  + T  A+  GA  +I KP   + + +  
Sbjct: 68  DGLGVIEKLNTMDIPKMP-KIIVLSAVGQD--KITQSAINLGADYYIVKPFDFV-VFINR 123

Query: 123 LKDEIIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARI-AVAIAASTGGPQSLL 181
           +++ +  ++ +    PR   E +  R   V+    ++  +   I  + + A   G   L 
Sbjct: 124 IRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIETEITNIIHEIGVPAHIKGYLYLR 183

Query: 182 KIFPKFPENLKAGILLVQHMPPGFTRSF 209
           +      +N++    + + + P   + F
Sbjct: 184 EAMKMVIDNVELLGAVTKELYPSIAKKF 211


>sp|P52938|SP0A_CLODI STAGE 0 SPORULATION PROTEIN A HOMOLOG >gi|1174099|gb|AAB05561.1|
           (U43514) phosphorylation-activated transcription factor
           spo0a [Clostridium difficile]
           Length = 274
           
 Score = 74.9 bits (181), Expect = 1e-12
 Identities = 50/208 (24%), Positives = 111/208 (53%), Gaps = 9/208 (4%)

Query: 7   KIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRM 66
           KI++++ DD+    +VLK+ ++++ ++++ G A+DGIEA+++V+K +PD++ LDV MP +
Sbjct: 8   KIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGIEALDLVKKTQPDLLILDVIMPHL 67

Query: 67  NGLDALRVI----MKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRE 122
           +GL  +  +    + K P  +I++SA+ Q+  + T  A+  GA  +I KP   + + +  
Sbjct: 68  DGLGVIEKLNTMDIPKMP-KIIVLSAVGQD--KITQSAINLGADYYIVKPFDFV-VFINR 123

Query: 123 LKDEIIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARI-AVAIAASTGGPQSLL 181
           +++ +  ++ +    PR   E +  R   V+    ++  +   I  + + A   G   L 
Sbjct: 124 IRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIETEITNIIHEIGVPAHIKGYLYLR 183

Query: 182 KIFPKFPENLKAGILLVQHMPPGFTRSF 209
           +      +N++    + + + P   + F
Sbjct: 184 EAMKMVIDNVELLGAVTKELYPSIAKKF 211


>pir||H70558 hypothetical protein Rv1626 - Mycobacterium tuberculosis  (strain
           H37RV) >gi|2113910|emb|CAB08879.1| (Z95554) hypothetical
           protein Rv1626 [Mycobacterium tuberculosis]
           Length = 205
           
 Score = 74.9 bits (181), Expect = 1e-12
 Identities = 51/154 (33%), Positives = 89/154 (57%), Gaps = 15/154 (9%)

Query: 9   RVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMNG 68
           RVL+ +D A +R  L +++  +   E+ GEA DG EA+E+ +  +PD+V +DV+MPR +G
Sbjct: 15  RVLIAEDEALIRMDLAEMLREEG-YEIVGEAGDGQEAVELAELHKPDLVIMDVKMPRRDG 73

Query: 69  LDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSS------SISINMRE 122
           +DA   I  K   P+++++A +Q   +   +A + GA+ ++ KP S      +I + +  
Sbjct: 74  IDAASEIASKRIAPIVVLTAFSQR--DLVERARDAGAMAYLVKPFSISDLIPAIELAVSR 131

Query: 123 LKDEIIAKIKEAAKVPRRFLELRRIRLLRVQKAK 156
            + EI A   E A +  R LE R++    V++AK
Sbjct: 132 FR-EITALEGEVATLSER-LETRKL----VERAK 159


>pir||T34653 probable response regulator - Streptomyces coelicolor
           >gi|4007689|emb|CAA22374.1| (AL034446) putative response
           regulator [Streptomyces coelicolor A3(2)]
           Length = 219
           
 Score = 74.9 bits (181), Expect = 1e-12
 Identities = 39/107 (36%), Positives = 66/107 (61%), Gaps = 5/107 (4%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           IRV++ DD A +R  L  I+++ P+LEV GE  DG   +++ ++ RPDVV +D+ MP ++
Sbjct: 5   IRVVICDDQALIRTGLATIVDAQPDLEVVGECGDGQTGVDLARELRPDVVVMDIRMPVLD 64

Query: 68  GLDALRVIM---KKYPVPVIMISALTQEGAEATIKALEYGAIDFIPK 111
           GL+A R++      +PV V++++    +  E   +AL  GA  F+ K
Sbjct: 65  GLEATRLLAGAGVAHPVKVLVVTTFNLD--EYVYEALRAGASGFLLK 109


>emb|CAB59507.1| (AL132648) putative two-component response regulator [Streptomyces
           coelicolor A3(2)]
           Length = 223
           
 Score = 74.9 bits (181), Expect = 1e-12
 Identities = 40/107 (37%), Positives = 68/107 (63%), Gaps = 5/107 (4%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           IRVL+VDD   +R   + I+ ++ +L V GEA DG++A++ V+  +PDVV +D+ MPRM+
Sbjct: 3   IRVLLVDDQPLLRTGFRMILEAEQDLAVVGEAGDGLQALDQVRALQPDVVLMDIRMPRMD 62

Query: 68  GLDALRVIM---KKYPVPVIMISALTQEGAEATIKALEYGAIDFIPK 111
           G++A R I    +  P  V++++    +  E  ++AL+ GA  F+ K
Sbjct: 63  GVEATRQITGPERDGPAKVLVLTTFDLD--EYVVEALKAGASGFLLK 107


>pir||T36318 two-component response regulator - Streptomyces coelicolor
           >gi|1293660|gb|AAB08053.1| (U51332) AbsA2 [Streptomyces
           coelicolor] >gi|4490635|emb|CAB38597.1| (AL035654) two
           component response regulator [Streptomyces coelicolor
           A3(2)]
           Length = 222
           
 Score = 74.5 bits (180), Expect = 2e-12
 Identities = 42/107 (39%), Positives = 63/107 (58%), Gaps = 3/107 (2%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           IRVL+ DD   +R  ++ I+ ++P +EV  EA DG EA+E+ +K RPDV  LD+ MP M+
Sbjct: 2   IRVLLADDETIIRAGVRSILTTEPGIEVVAEASDGREAVELARKHRPDVALLDIRMPEMD 61

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATI-KALEYGAIDFIPKPS 113
           GL A   +    P   +++  LT  G +  I +AL+ G   F+ K S
Sbjct: 62  GLTAAGEMRTTNPDTAVVV--LTTFGEDRYIERALDQGVAGFLLKAS 106


>pir||T36530 probable two-component system regulator - Streptomyces coelicolor
           >gi|4753864|emb|CAB42027.1| (AL049754) putative
           two-component system regulator [Streptomyces coelicolor
           A3(2)]
           Length = 228
           
 Score = 74.5 bits (180), Expect = 2e-12
 Identities = 39/112 (34%), Positives = 68/112 (59%), Gaps = 3/112 (2%)

Query: 5   GRKIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMP 64
           GR IRVL+ DD   +R+    ++N+ P++EV G+A DG++A+  V +  P+VV +D+ MP
Sbjct: 7   GRVIRVLIADDQQMVRQGFTVLLNTQPDIEVIGQAVDGLDAVAKVAELAPEVVLMDIRMP 66

Query: 65  RMNGLDALRVIMKKYP-VPVIMISALTQEGAEATIKALEYGAIDFIPKPSSS 115
            + G++A R I    P + V++++    +  E   +AL  GA  F+ K +S+
Sbjct: 67  ELGGIEATRRITTATPEIRVLVLTTFDLD--EYVYEALRAGASGFLLKDASA 116


>pir||A70080 two-component response regulator [YxjM] homolog yxjL - Bacillus
           subtilis >gi|1783236|dbj|BAA11713.1| (D83026) homologous
           to many transcriptional activator proteins; hypothetical
           [Bacillus subtilis] >gi|2636426|emb|CAB15917.1| (Z99123)
           similar to two-component response regulator [YxjM]
           [Bacillus subtilis]
           Length = 218
           
 Score = 74.1 bits (179), Expect = 2e-12
 Identities = 42/130 (32%), Positives = 74/130 (56%), Gaps = 10/130 (7%)

Query: 7   KIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRM 66
           KIRV + DD   +R+  + +IN+  ++ V GEA DG + I + ++ +PDV+ +DV+MPR 
Sbjct: 5   KIRVALADDQPLVREGFRYVINAQTDMTVSGEAGDGHDIIALAKQTKPDVILMDVQMPRC 64

Query: 67  NGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDE 126
           +G++A + IM   P   I+I   T +  E   + +  GA+ ++ K +         L +E
Sbjct: 65  SGIEAAKDIMSALPNTKIVI-LTTFDTEEYVFEGIRAGAVGYLLKDT---------LPEE 114

Query: 127 IIAKIKEAAK 136
           +I  I+ AA+
Sbjct: 115 LIDAIRAAAR 124


>pir||G69780 two-component response regulator [YdfH] homolog ydfI - Bacillus
           subtilis >gi|1881349|dbj|BAA19376.1| (AB001488) PROBABLE
           REGULATORY COMPONENT OF SENSORY TRANSDUCTION SYSTEM.
           [Bacillus subtilis] >gi|2632842|emb|CAB12349.1| (Z99106)
           similar to two-component response regulator [YdfH]
           [Bacillus subtilis]
           Length = 213
           
 Score = 74.1 bits (179), Expect = 2e-12
 Identities = 34/107 (31%), Positives = 68/107 (62%), Gaps = 2/107 (1%)

Query: 9   RVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMNG 68
           +VL+VDD   +R+ LK +I ++ +  + GEA +G  A+ +  +  PD++ +D+ MP M+G
Sbjct: 3   KVLIVDDHLVVREGLKLLIETNDQYTIIGEAENGKVAVRLADELEPDIILMDLYMPEMSG 62

Query: 69  LDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSS 115
           L+A++ I +K+  P+I+++   ++     I+ +E GA  ++ K +SS
Sbjct: 63  LEAIKQIKEKHDTPIIILTTYNED--HLMIEGIELGAKGYLLKDTSS 107


>pir||T35281 probable two component response regulator - Streptomyces coelicolor
           >gi|5578847|emb|CAB51249.1| (AL096872) putative two
           component response regulator [Streptomyces coelicolor
           A3(2)]
           Length = 227
           
 Score = 74.1 bits (179), Expect = 2e-12
 Identities = 44/129 (34%), Positives = 72/129 (55%), Gaps = 10/129 (7%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           IRVL+ DD A +R   + +++S+P++EV GEA DG EA  +  + R DVV +D+ MP  +
Sbjct: 3   IRVLLADDQALLRSAFRVLVDSEPDMEVVGEASDGAEAARLAAEQRADVVLMDIRMPGTD 62

Query: 68  GLDALRVIMKKYPVPVIMISALTQ-EGAEATIKALEYGAIDFIPKPSSSISINMRELKDE 126
           GL A R+I     +  + +  LT  E  +  +++L  GA  F+ K S           +E
Sbjct: 63  GLAATRMISADPSLAHVRVVILTTFEVDDYVVQSLRAGASGFLGKGSE---------PEE 113

Query: 127 IIAKIKEAA 135
           +++ I+ AA
Sbjct: 114 LLSAIRVAA 122


>pir||H75381 DNA-binding response regulator - Deinococcus radiodurans  (strain
           R1) >gi|6459320|gb|AAF11120.1|AE001999_4 (AE001999)
           DNA-binding response regulator [Deinococcus radiodurans]
           Length = 225
           
 Score = 74.1 bits (179), Expect = 2e-12
 Identities = 55/168 (32%), Positives = 92/168 (54%), Gaps = 13/168 (7%)

Query: 3   LTGRKIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVE 62
           +T   +RVL+VDD A +R+ L+  +  D  +EV GEA +G EA++  ++ RP+VV +D+ 
Sbjct: 9   MTTPTVRVLLVDDHAVVRQGLRLFLGLDEGIEVVGEAANGEEALQEAERLRPEVVVMDLM 68

Query: 63  MPRMNGLDALRVIMKKYPVPVIMISALTQEGAEATIK-ALEYGAIDFIPKPSSSISINMR 121
           MP M+G+ A R + ++ P   ++  ALT    E  +  A+E GAI ++ K +SS      
Sbjct: 69  MPVMDGITATRELRRRLPDTEVI--ALTSTLEENKVNGAIEAGAISYMLKDASS------ 120

Query: 122 ELKDEIIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSV-PARIAV 168
              D +   I  AA+   R       RL+R  ++ +++ S+ P   AV
Sbjct: 121 ---DTLADAIHAAARGEVRLHPEAARRLVRDFRSPEMRESLTPKETAV 165


>emb|CAB54571.1| (AJ006393) response regulator [Streptococcus pneumoniae]
           Length = 210
           
 Score = 73.4 bits (177), Expect = 4e-12
 Identities = 38/108 (35%), Positives = 65/108 (60%), Gaps = 1/108 (0%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           +++L+VDD   +R  LK   +   ++EV GEA +G + I++  + RPDV+ +D+ MP MN
Sbjct: 1   MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMN 60

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSS 115
           G+DA   I+K++P   I+I     +  E  +  L+ GA  ++ K SS+
Sbjct: 61  GIDATLAILKEWPEAKILIVTSYLDN-EKIMPVLDAGAKGYMLKTSSA 107


>emb|CAB87987.1| (AJ288948) Spo0A protein [Clostridium cellulolyticum]
           Length = 292
           
 Score = 73.4 bits (177), Expect = 4e-12
 Identities = 45/129 (34%), Positives = 78/129 (59%), Gaps = 9/129 (6%)

Query: 3   LTGRKIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVE 62
           L+ +KI VL+ DD+     +L + +++  ++EV G ARDG EA++++ +  PD+  LD+ 
Sbjct: 12  LSSKKIEVLIADDNREFGDILCEYLSNQEDIEVVGLARDGFEAVDLILQNTPDIAILDII 71

Query: 63  MPRMNGLDALRVI----MKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKP--SSSI 116
           MP ++GL  L  I    ++K P+  I++SA+ Q+  + T +AL  GA  +I KP     +
Sbjct: 72  MPHLDGLGVLEKIASSNLEKKPL-FIVLSAVGQD--KITQRALSLGAEYYIVKPFDMDVL 128

Query: 117 SINMRELKD 125
              +R+LKD
Sbjct: 129 VSRIRQLKD 137


>pir||T36528 probable two-component system regulator - Streptomyces coelicolor
           >gi|4753862|emb|CAB42025.1| (AL049754) putative
           two-component system regulator [Streptomyces coelicolor
           A3(2)]
           Length = 221
           
 Score = 73.4 bits (177), Expect = 4e-12
 Identities = 42/120 (35%), Positives = 70/120 (58%), Gaps = 6/120 (5%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           IRVL+ DD   +R+    ++N+ P++EV GEA +G EA+  V++  PDVV +D+ MP +N
Sbjct: 3   IRVLIADDQMMVREGFSVLLNAMPDIEVAGEAVNGREAVAKVRELSPDVVLMDIRMPELN 62

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEI 127
           G++A R I+       +++   T +  E   +AL  GA  F+ K +S+     R+L D +
Sbjct: 63  GIEATREIVAADSTSKVLV-LTTFDLDEYVYQALRAGASGFLLKDASA-----RQLADGV 116


>pir||T30314 chpB protein - Pseudomonas aeruginosa >gi|11351447|pir||F83594
           probable methylesterase PA0414 [imported] - Pseudomonas
           aeruginosa (strain PAO1) >gi|3241970|gb|AAC23932.1|
           (U79580) ChpB [Pseudomonas aeruginosa]
           >gi|9946269|gb|AAG03803.1|AE004478_8 (AE004478) probable
           methylesterase [Pseudomonas aeruginosa]
           Length = 343
           
 Score = 73.0 bits (176), Expect = 5e-12
 Identities = 79/354 (22%), Positives = 141/354 (39%), Gaps = 44/354 (12%)

Query: 9   RVLVVDDSAFMRKVLKD---------IINSDPELEVCGEARDGIEAIEMVQKCRPDVVTL 59
           RV V+ D++  R VL+          ++N+DP       AR    A+E    C PD+  +
Sbjct: 8   RVAVIADTSLQRHVLQQALLGHGYEVVLNADP-------ARVDDAALE----CAPDLWLV 56

Query: 60  DVEMPRMNGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAID----FIPKPSSS 115
           D  + + +    L  ++++   PV+       E         E   I      I  PS  
Sbjct: 57  D--LTQQDDSPLLDSLLEQDRAPVLFGEGHAPERHTEHYPRWERRLIGKLKRLIGDPSDG 114

Query: 116 ISINMRELKDEIIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAIAASTG 175
           +  ++  L DE         + PR       + +     A  ++    AR    +AAS G
Sbjct: 115 VGDSLGALLDE--------ERPPR-------LEIPGDLAAMPLQAGEAAREVWLLAASLG 159

Query: 176 GPQSLLKIFPKFPENLKAGILLVQHMPPGFTRSFAKRLDSVSKIDVKEAEEGDVVEEGKA 235
           GP ++       P  L  G L  QH+   F ++  + +   S+  VK   +G+ +  G+ 
Sbjct: 160 GPAAVKAFLDALPGGLPIGFLYAQHIDASFEQNLPQAVGRHSQWHVKNVRDGEALRCGEV 219

Query: 236 YVAPGDYHMEVTLRGGKPVITLNKKPKMHGVRPAADPMMITAAQVFGRRTVGVVMTGMGR 295
            V P  + +     G    +  +++       P+ D MM+  AQ FG     +V +GMG 
Sbjct: 220 MVVPVLHELGFHHDGR---LKCSQRSWPEPYTPSIDQMMLNLAQQFGPDCGVIVFSGMGS 276

Query: 296 DGAQGIVEIKKRGGITIAQDEKTSIIFGMPKAAIETGMVDYVVPLEKIPETVVR 349
           DG+     ++++GG    Q   + +   MP +  E G   +     ++ E +V+
Sbjct: 277 DGSAAAAYVRRQGGEVWTQRADSCVCSSMPDSLREAGYSSFNASPRELAEALVK 330


>pir||T35166 probable two-component regulator - Streptomyces coelicolor
           >gi|3334798|emb|CAA19946.1| (AL031107) putative
           two-component regulator [Streptomyces coelicolor A3(2)]
           Length = 222
           
 Score = 73.0 bits (176), Expect = 5e-12
 Identities = 39/104 (37%), Positives = 60/104 (57%), Gaps = 2/104 (1%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           +RV+V DD   +R     I+ + P++EV  EA DG EA+  V++  PDV+ LD+ MP M+
Sbjct: 3   VRVVVADDQELVRSGFSMILEAQPDIEVVAEAGDGAEAVAAVERYAPDVLLLDIRMPVMD 62

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPK 111
           GLDA R +  +    V+M++    +  E   +AL  GA  F+ K
Sbjct: 63  GLDAARRVCARSACKVVMLTTFDLD--EYVYEALYAGASGFLLK 104


>pir||T36862 probable two-component response regulator - Streptomyces coelicolor
           >gi|5123537|emb|CAB45293.1| (AL079332) putative two
           component response regulator [Streptomyces coelicolor
           A3(2)]
           Length = 210
           
 Score = 73.0 bits (176), Expect = 5e-12
 Identities = 37/105 (35%), Positives = 66/105 (62%), Gaps = 3/105 (2%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           I+VL+VDD   +R+ L+  +    ++EV GEA DG E ++  Q+ +PDV+ +DV+MP M+
Sbjct: 2   IKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAADGAEGVDRAQELKPDVILMDVKMPGMD 61

Query: 68  GLDALRVIMK-KYPVPVIMISALTQEGAEATIKALEYGAIDFIPK 111
           G+DALR + +      V+++++ T++     + AL  GA  ++ K
Sbjct: 62  GVDALRRLRELDNHARVLVVTSFTEQ--RTVVPALRAGAAGYVYK 104


>sp|P33356|YEHT_ECOLI HYPOTHETICAL 27.9 KD PROTEIN IN MOLR-BGLX INTERGENIC REGION
           >gi|7449507|pir||D64980 yehT protein - Escherichia coli
           (strain K-12) >gi|405856|gb|AAA60488.1| (U00007) yehT
           [Escherichia coli] >gi|2367130|gb|AAC75186.1| (AE000301)
           orf, hypothetical protein [Escherichia coli K12]
           >gi|744225|prf||2014253V yehT gene [Escherichia coli]
           Length = 244
           
 Score = 72.6 bits (175), Expect = 7e-12
 Identities = 36/105 (34%), Positives = 63/105 (59%), Gaps = 4/105 (3%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           I+VL+VDD    R+ L+  +    ++E+ GE  + +E I  V K RPDV+ LD++MPR++
Sbjct: 7   IKVLIVDDEPLARENLRVFLQEQSDIEIVGECSNAVEGIGAVHKLRPDVLFLDIQMPRIS 66

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKP 112
           GL+ + ++  ++   ++ ++A      E  IKA E  A D++ KP
Sbjct: 67  GLEMVGMLDPEHRPYIVFLTAFD----EYAIKAFEEHAFDYLLKP 107


>gb|AAC33471.1| (AF074950) CheY [Treponema denticola]
           Length = 146
           
 Score = 72.6 bits (175), Expect = 7e-12
 Identities = 49/111 (44%), Positives = 67/111 (60%), Gaps = 6/111 (5%)

Query: 5   GRKIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRP--DVVTLDVE 62
           G   ++LVVDDS F+ K +  I+NS+   EV   A DG E +E  ++  P  D+VT+D+ 
Sbjct: 22  GTPYKILVVDDSIFVTKQIGQILNSEG-YEVVATAVDGFEGVEKYKELCPNVDLVTMDIT 80

Query: 63  MPRMNGLDALRVIMK-KYPVPVIMISALTQEGAEATIKALEYGAIDFIPKP 112
           MP+M+GL AL  IM       V+MISAL +E  E   KAL  GA ++I KP
Sbjct: 81  MPKMDGLTALEQIMAFDKNAKVVMISALGKE--ELVKKALLLGAKNYIVKP 129


>pdb|1DZ3|A Chain A, Domain-Swapping In The Sporulation Response Regulator
           Spo0a
           Length = 130
           
 Score = 72.6 bits (175), Expect = 7e-12
 Identities = 41/107 (38%), Positives = 68/107 (63%), Gaps = 4/107 (3%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           I+V + DD+  +  +L + I+S P++EV G A +G + ++M+++ RPD++ LD+ MP ++
Sbjct: 3   IKVCIADDNRELVSLLDEYISSQPDMEVIGTAYNGQDCLQMLEEKRPDILLLDIIMPHLD 62

Query: 68  GLDALRVIMK--KYPVPVIMISALTQEGAEATIKALEYGAIDFIPKP 112
           GL  L  I    ++   VIM++A  QE  + T KA+E GA  FI KP
Sbjct: 63  GLAVLERIRAGFEHQPNVIMLTAFGQE--DVTKKAVELGASYFILKP 107


>emb|CAB90919.1| (AL355774) putative DNA-binding response regulator [Streptomyces
           coelicolor A3(2)]
           Length = 252
           
 Score = 72.6 bits (175), Expect = 7e-12
 Identities = 43/128 (33%), Positives = 71/128 (54%), Gaps = 10/128 (7%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           IRVLVVDD A  R+ L+ ++ ++ +++V GEA DG EA+E      PD+V +DV MP+  
Sbjct: 36  IRVLVVDDHALFRRGLEIVLAAEEDIQVVGEAGDGAEAVEKAADLLPDIVLMDVRMPKRG 95

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEI 127
           G++A   I +  P   I++  ++ E A+    A++ GA  ++ K  S+         DE+
Sbjct: 96  GIEACTSIKEVAPSAKIIMLTISDEEAD-LYDAIKAGATGYLLKEIST---------DEV 145

Query: 128 IAKIKEAA 135
              I+  A
Sbjct: 146 ATAIRAVA 153


>emb|CAB95289.1| (AL359779) putative two component system response regulator
           [Streptomyces coelicolor A3(2)]
           Length = 221
           
 Score = 72.6 bits (175), Expect = 7e-12
 Identities = 39/105 (37%), Positives = 63/105 (59%), Gaps = 1/105 (0%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           IRVL+ DD + +R   + ++++ P++EV  EA DG EA+  +++ RPDVV +D+ MP ++
Sbjct: 2   IRVLLADDQSLVRAGFRALLDAQPDIEVVAEAADGEEAVRSIRELRPDVVLMDIRMPLLD 61

Query: 68  GLDALRVIMKKYPVPVIMISALTQ-EGAEATIKALEYGAIDFIPK 111
           GL A R I     +P + +  LT  E  E   +A+  GA  F+ K
Sbjct: 62  GLAATRRITGDPGLPDVRVVMLTTFELDEYVFEAIRSGASGFLVK 106


>sp|P37478|YYCF_BACSU HYPOTHETICAL 27.2 KD SENSORY TRANSDUCTION PROTEIN IN ROCR-PURA
           INTERGENIC REGION >gi|2126981|pir||S65967 two-component
           response regulator yycF - Bacillus subtilis
           >gi|467327|dbj|BAA05173.1| (D26185) unknown [Bacillus
           subtilis] >gi|1064814|dbj|BAA11300.1| (D78193)
           homologous to sp:PHOP_BACSUB [Bacillus subtilis]
           >gi|2636588|emb|CAB16078.1| (Z99124) similar to
           two-component response regulator [YycG] [Bacillus
           subtilis]
           Length = 235
           
 Score = 72.2 bits (174), Expect = 9e-12
 Identities = 42/124 (33%), Positives = 73/124 (58%), Gaps = 9/124 (7%)

Query: 9   RVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMNG 68
           ++LVVDD   +  +L+  +  +     C  A DG EA+EMV++ +PD++ LD+ +P  +G
Sbjct: 4   KILVVDDEKPIADILEFNLRKEGYEVHC--AHDGNEAVEMVEELQPDLILLDIMLPNKDG 61

Query: 69  LDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEII 128
           ++  R + KKY +P+IM++A   E  +  +  LE GA D++ KP S+     REL   + 
Sbjct: 62  VEVCREVRKKYDMPIIMLTAKDSEIDK--VIGLEIGADDYVTKPFST-----RELLARVK 114

Query: 129 AKIK 132
           A ++
Sbjct: 115 ANLR 118


>pir||S58645 response regulator cheY [validated] - Halobacterium salinarum
           >gi|994802|emb|CAA60161.1| (X86407) cheY [Halobacterium
           salinarum] >gi|10580529|gb|AAG19395.1| (AE005033)
           chemotaxis protein; CheY [Halobacterium sp. NRC-1]
           Length = 120
           
 Score = 72.2 bits (174), Expect = 9e-12
 Identities = 45/122 (36%), Positives = 75/122 (60%), Gaps = 6/122 (4%)

Query: 9   RVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMNG 68
           +VL+VDDS FMR +L++I+  + E E+  EA +G+EA+EM ++  PD+V +D+ MP  +G
Sbjct: 4   QVLLVDDSEFMRNLLREIL--EEEFEIADEAENGVEAVEMYKEYDPDLVMMDIVMPIRDG 61

Query: 69  LDALRVIMK-KYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEI 127
           ++A   I +      +IM +++ QE  E   KA++ GA  +I KP    S+ M  + D +
Sbjct: 62  IEATSEIKEFDAGAHIIMCTSIGQE--EKMKKAVKAGADGYITKPFQKPSV-MDAISDVL 118

Query: 128 IA 129
            A
Sbjct: 119 TA 120


>pir||I40540 vsrD protein - Pseudomonas solanacearum >gi|603069|gb|AAA66240.1|
           (U18135) VsrD [Ralstonia solanacearum]
           Length = 210
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 36/108 (33%), Positives = 66/108 (60%), Gaps = 3/108 (2%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           IRVL+ DD   +R  L+  ++ + ++EV GEA  G E +E ++    DVV LD+ MP  N
Sbjct: 2   IRVLIADDHEIVRAGLRQFLSEERDIEVAGEAASGEEVMEQLRTEAFDVVVLDISMPDRN 61

Query: 68  GLDALRVIMKKYP-VPVIMISALTQEGAEATIKALEYGAIDFIPKPSS 114
           G+D L+++ +++P +PV+++S   ++  +  I  +  GA  ++ K S+
Sbjct: 62  GIDTLKLVRQRHPDLPVLILSTFPED--QYAINLIRAGASGYLTKESA 107


>dbj|BAA88407.1| (AB016841) chiR [Streptomyces thermoviolaceus]
           Length = 213
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 44/129 (34%), Positives = 72/129 (55%), Gaps = 11/129 (8%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           IRVLV +D + +R  L  I+ S P +EV GEA DG  A+++ +  RPDVV +DV MPR++
Sbjct: 2   IRVLVAEDQSAVRAGLVLILRSAPGIEVAGEAEDGQRAVDLARDLRPDVVLMDVRMPRLD 61

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEI 127
           G+ A R I+ +    V++++  T +       AL  GA  F+ K + +         D++
Sbjct: 62  GVSATRQIVAEQLADVLVLT--TFDFDAYVFGALRAGAAGFLLKSAEA---------DDL 110

Query: 128 IAKIKEAAK 136
           I  ++  A+
Sbjct: 111 IDAVRTVAR 119


>dbj|BAB05816.1| (AP001514) two-component response regulator [Bacillus halodurans]
           Length = 210
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 46/163 (28%), Positives = 95/163 (58%), Gaps = 9/163 (5%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           I+VL+ +D   +R+ LK +I +D ++ V GEA +G EAI + +  R DV  LD+ MP M+
Sbjct: 2   IKVLLAEDQVMVRQGLKVMIETDEDIFVTGEATNGKEAIRLCESQRFDVAVLDIRMPEMD 61

Query: 68  GLDALRVIMKKYP-VPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDE 126
           G++A +V+  ++P + ++M++  T +  +  ++AL+ G   ++ K   + S+ +R +K  
Sbjct: 62  GIEAAKVLRSRFPEMKILMLT--TFDDHQYVMEALKLGVSGYMLKDGDTESL-IRSIKSA 118

Query: 127 IIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSV-PARIAV 168
           +   +    +V  + + +    LL+ ++A  + P++ P  IA+
Sbjct: 119 LNGGLSLEDQVAAKVMPV----LLQHEEAIPIDPTLTPREIAI 157


>gb|AAB07804.1| (U01971) MtrA [Mycobacterium tuberculosis]
           Length = 225
           
 Score = 71.4 bits (172), Expect = 2e-11
 Identities = 45/142 (31%), Positives = 76/142 (52%), Gaps = 11/142 (7%)

Query: 9   RVLVVDDSAFMRKVLKDIINSDP-ELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           R+LVVDD A + ++L  ++  +  +  V G   DG +A+  V++ RPD+V LD+ +P MN
Sbjct: 4   RILVVDDDASLAEMLTIVLRGEGFDTAVIG---DGTQALTAVRELRPDLVLLDLMLPGMN 60

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEI 127
           G+D  RV+     VP++M++A T       +  LE GA D+I KP        +EL   +
Sbjct: 61  GIDVCRVLRADSGVPIVMLTAKTD--TVDVVLGLESGADDYIMKP-----FKPKELVARV 113

Query: 128 IAKIKEAAKVPRRFLELRRIRL 149
            A+++     P   L +  + +
Sbjct: 114 RARLRRNDDEPAEMLSIADVEI 135


>pir||H70592 probable mtrA protein - Mycobacterium tuberculosis (strain H37RV)
           >gi|2072713|emb|CAB08347.1| (Z95121) mtrA [Mycobacterium
           tuberculosis]
           Length = 228
           
 Score = 71.4 bits (172), Expect = 2e-11
 Identities = 45/142 (31%), Positives = 76/142 (52%), Gaps = 11/142 (7%)

Query: 9   RVLVVDDSAFMRKVLKDIINSDP-ELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           R+LVVDD A + ++L  ++  +  +  V G   DG +A+  V++ RPD+V LD+ +P MN
Sbjct: 7   RILVVDDDASLAEMLTIVLRGEGFDTAVIG---DGTQALTAVRELRPDLVLLDLMLPGMN 63

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEI 127
           G+D  RV+     VP++M++A T       +  LE GA D+I KP        +EL   +
Sbjct: 64  GIDVCRVLRADSGVPIVMLTAKTD--TVDVVLGLESGADDYIMKP-----FKPKELVARV 116

Query: 128 IAKIKEAAKVPRRFLELRRIRL 149
            A+++     P   L +  + +
Sbjct: 117 RARLRRNDDEPAEMLSIADVEI 138


>pir||T34675 probable response regulator - Streptomyces coelicolor
           >gi|4007711|emb|CAA22396.1| (AL034446) putative response
           regulator [Streptomyces coelicolor A3(2)]
           Length = 260
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 38/106 (35%), Positives = 65/106 (60%), Gaps = 3/106 (2%)

Query: 7   KIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRM 66
           KIR+L+ DD A +R+ ++ I++ +P+LEV  EA DG EAI+M +    D+  LD+ MPR+
Sbjct: 47  KIRILLADDHALVRRGVRLILDREPDLEVVAEAGDGAEAIDMARAHEADLAVLDIAMPRL 106

Query: 67  NGLDALRVIMKKYP-VPVIMISALTQEGAEATIKALEYGAIDFIPK 111
            GL A R +    P + ++M++    +  +   +AL+ GA  ++ K
Sbjct: 107 TGLQAARELAALKPGLRILMLT--MHDNEQYLFQALKSGACGYVLK 150


>sp|P52932|SP0A_BACME STAGE 0 SPORULATION PROTEIN A >gi|497955|gb|AAA18875.1| (U09974)
           Spo0A [Bacillus megaterium]
           Length = 212
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 44/110 (40%), Positives = 69/110 (62%), Gaps = 5/110 (4%)

Query: 6   RKIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPR 65
           +KI+V +VDD+  +  +L+D I+   ++EV G A +G E + +++   PDV+ LD+ MP 
Sbjct: 2   KKIKVCLVDDNRELIGLLEDYISEQEDMEVIGVAYNGQECLSILKDKNPDVLVLDIIMPH 61

Query: 66  MNGLDALRVI--MKKYPVP-VIMISALTQEGAEATIKALEYGAIDFIPKP 112
           ++GL  L  +  MKK   P VIM++A  QE  + T KA++ GA  FI KP
Sbjct: 62  LDGLAVLGQLKEMKKENYPNVIMLTAFGQE--DVTKKAVDLGAAYFILKP 109


>pir||F70645 hypothetical protein Rv3133c - Mycobacterium tuberculosis  (strain
           H37RV) >gi|1781234|emb|CAB06281.1| (Z83867) hypothetical
           protein Rv3133c [Mycobacterium tuberculosis]
           >gi|4335782|gb|AAD17452.1| (U22037) DevR [Mycobacterium
           tuberculosis]
           Length = 217
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 40/119 (33%), Positives = 70/119 (58%), Gaps = 4/119 (3%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           ++V +VDD   +R+ L D++ +DPEL+V GEA    EA+  V   RPDV  LDV +P  N
Sbjct: 2   VKVFLVDDHEVVRRGLVDLLGADPELDVVGEAGSVAEAMARVPAARPDVAVLDVRLPDGN 61

Query: 68  GLDALRVIMKKYP-VPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKD 125
           G++  R ++ + P +  +++++ T +  EA + A+  GA  ++ K    + +  R +KD
Sbjct: 62  GIELCRDLLSRMPDLRCLILTSYTSD--EAMLDAILAGASGYVVKDIKGMEL-ARAVKD 117


>pir||S60872 phosphorylation-activated transcription factor Spo0A - Bacillus
           megaterium (fragment)
           Length = 213
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 44/110 (40%), Positives = 69/110 (62%), Gaps = 5/110 (4%)

Query: 6   RKIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPR 65
           +KI+V +VDD+  +  +L+D I+   ++EV G A +G E + +++   PDV+ LD+ MP 
Sbjct: 2   KKIKVCLVDDNRELIGLLEDYISEQEDMEVIGVAYNGQECLSILKDKNPDVLVLDIIMPH 61

Query: 66  MNGLDALRVI--MKKYPVP-VIMISALTQEGAEATIKALEYGAIDFIPKP 112
           ++GL  L  +  MKK   P VIM++A  QE  + T KA++ GA  FI KP
Sbjct: 62  LDGLAVLGQLKEMKKENYPNVIMLTAFGQE--DVTKKAVDLGAAYFILKP 109


>pir||F75593 DNA-binding response regulator - Deinococcus radiodurans  (strain
           R1) >gi|6460582|gb|AAF12288.1|AE001862_114 (AE001862)
           DNA-binding response regulator [Deinococcus radiodurans]
           Length = 211
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 51/179 (28%), Positives = 93/179 (51%), Gaps = 11/179 (6%)

Query: 1   MPLTGR---KIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVV 57
           +P TG     IRVL+ +D   +   L  +++ + +L+V G A DG EA+  V   RPDV+
Sbjct: 3   LPETGAGSSPIRVLLAEDQTLVLGALAALLSLEDDLDVVGTAADGAEALMQVHTLRPDVL 62

Query: 58  TLDVEMPRMNGLDALRVIMKKYP-VPVIMISALTQEGAEATIKALEYGAIDFIPK--PSS 114
             D+EMPR++GLD    + ++ P   V++++  T+ G     +AL+ GA  ++ K  PS 
Sbjct: 63  VTDIEMPRLSGLDLAERVRQEAPQTRVVIVTTFTRAG--YLRRALDAGARGYLLKDAPSH 120

Query: 115 SISINMRELK---DEIIAKIKEAAKVPRRFLELRRIRLLRVQKAKKVKPSVPARIAVAI 170
            ++  +R +      I A + E     +  L  R I++LR  +  +   ++ A + + +
Sbjct: 121 ELADAIRRVHAGGRAIDAGLAEEIWDAQSPLTEREIQVLRAAETGRSTAAIAAELGIGV 179


>pir||C81104 transcription regulator, LuxR family NMB1250 [imported] - Neisseria
           meningitidis (group B strain MD58, group A strain Z2491)
           >gi|7226490|gb|AAF41630.1| (AE002473) transcriptional
           regulator, LuxR family [Neisseria meningitidis MC58]
           >gi|7380078|emb|CAB84659.1| (AL162755) putative
           two-component system response regulator [Neisseria
           meningitidis Z2491]
           Length = 218
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 39/129 (30%), Positives = 75/129 (57%), Gaps = 10/129 (7%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           I+++++DD    R  +K +++     EV GEA DG+  I+M+ + +PDVV LD++MP MN
Sbjct: 3   IKIILIDDHTLFRSGIKALLSRQHGFEVIGEAADGLSGIKMISRLQPDVVLLDLDMPGMN 62

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEI 127
           G +AL  I+   P   +++  ++++  + T + +  GA  ++ K     +IN     D +
Sbjct: 63  GREALSQIISINPQQAVIMLTVSEDSDDLT-ECMRIGARGYLLK-----NIN----ADFL 112

Query: 128 IAKIKEAAK 136
           +  I++AA+
Sbjct: 113 LESIRKAAE 121


>pir||H82218 transcription regulator LuxR family VC1277 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9655763|gb|AAF94436.1| (AE004207) transcriptional
           regulator, LuxR family [Vibrio cholerae]
           Length = 216
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 36/113 (31%), Positives = 70/113 (61%), Gaps = 1/113 (0%)

Query: 6   RKIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPR 65
           + IRV++VDD   +       +  +PE+EV   A +G+EA+E+V+  +PDVV +DV MP 
Sbjct: 7   KPIRVVMVDDHQVVLDGFIARLEQEPEIEVVATASNGLEALELVKLHQPDVVLMDVSMPI 66

Query: 66  MNGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISI 118
           MNG++A R+I ++ P   +++  +  +  E  ++ ++ GA+ ++ K  S++ +
Sbjct: 67  MNGIEATRLIKEEVPHTKVLMLTM-HDNREYIMQVMQAGAMGYMLKEISALKM 118


>dbj|BAB05842.1| (AP001514) two-component response regulator [Bacillus halodurans]
           Length = 223
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 38/105 (36%), Positives = 66/105 (62%), Gaps = 3/105 (2%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           I VL+ DD   MR+ LK II+ + ++ V G A++G E ++ +    P V+ +D++MP MN
Sbjct: 4   INVLIADDQTLMREGLKTIIDLEDDMNVTGLAKNGKEVLDQIPCLLPHVILMDIQMPIMN 63

Query: 68  GLDALRVIMKKYP-VPVIMISALTQEGAEATIKALEYGAIDFIPK 111
           G++ L+V+ + YP + V+M++  T E  +  I++L  GA  F+ K
Sbjct: 64  GIECLKVVKRIYPHINVLMLT--TFEDDDYIIESLVGGANGFLLK 106


>dbj|BAB05932.1| (AP001514) two-component response regulator [Bacillus halodurans]
           Length = 217
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 39/99 (39%), Positives = 64/99 (64%), Gaps = 3/99 (3%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           IR+ VVDD   +RK L   + +  +  + GEA DG  A+ +V+K +PD+V +DV MP +N
Sbjct: 3   IRIAVVDDHHVVRKGLIYFLETYHDFTIVGEAEDGEAALTLVEKVQPDIVLMDVIMPGIN 62

Query: 68  GLDALRVIMKKYP-VPVIMISALTQEGAEATIKALEYGA 105
           G++A + I +K+P V V+++S+  +   E+ I AL+ GA
Sbjct: 63  GIEATKKIKQKWPTVHVVVLSSSAER--ESVIPALQAGA 99


>dbj|BAB07746.1| (AP001520) two-component response regulator [Bacillus halodurans]
           Length = 236
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 40/124 (32%), Positives = 72/124 (57%), Gaps = 9/124 (7%)

Query: 9   RVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMNG 68
           ++LVVDD   +  +LK  +  +    +C  A DG EA+E V + +PD++ LD+ +P  +G
Sbjct: 5   KILVVDDEKPIADILKFNLEKEGFTVIC--AYDGAEAVEQVNQEKPDLILLDIMLPNKDG 62

Query: 69  LDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEII 128
           ++  R + K++ +P+IM++A   E  +  +  LE GA D++ KP S+     REL   + 
Sbjct: 63  MEVCREVRKQFEMPIIMLTAKDSEIDK--VLGLELGADDYVTKPFST-----RELLARVK 115

Query: 129 AKIK 132
           A ++
Sbjct: 116 ANLR 119


>sp|P52940|SP0A_CLOPA STAGE 0 SPORULATION PROTEIN A HOMOLOG >gi|497971|gb|AAA18883.1|
           (U09982) Spo0A [Clostridium pasteurianum]
           Length = 273
           
 Score = 70.2 bits (169), Expect = 3e-11
 Identities = 41/109 (37%), Positives = 70/109 (63%), Gaps = 5/109 (4%)

Query: 7   KIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRM 66
           KI VL+ DD+     +L D + +  ++ V G A+DGIEA++++++ +PD+V LD+ MP M
Sbjct: 5   KISVLIADDNKEFCNILNDYLLNQSDIVVVGIAKDGIEALKLIEEKKPDLVILDIIMPNM 64

Query: 67  NGLDALRVI--MKKYPVP-VIMISALTQEGAEATIKALEYGAIDFIPKP 112
           +GL  L  +  +   PVP VI++SA+ Q+  + T +A+  GA  ++ KP
Sbjct: 65  DGLVVLEKLANINIDPVPNVIVLSAVGQD--KITQRAITLGADYYVVKP 111


>pir||S60880 phosphorylation-activated transcription factor Spo0A - Clostridium
           pasteurianum
           Length = 274
           
 Score = 70.2 bits (169), Expect = 3e-11
 Identities = 41/109 (37%), Positives = 70/109 (63%), Gaps = 5/109 (4%)

Query: 7   KIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRM 66
           KI VL+ DD+     +L D + +  ++ V G A+DGIEA++++++ +PD+V LD+ MP M
Sbjct: 5   KISVLIADDNKEFCNILNDYLLNQSDIVVVGIAKDGIEALKLIEEKKPDLVILDIIMPNM 64

Query: 67  NGLDALRVI--MKKYPVP-VIMISALTQEGAEATIKALEYGAIDFIPKP 112
           +GL  L  +  +   PVP VI++SA+ Q+  + T +A+  GA  ++ KP
Sbjct: 65  DGLVVLEKLANINIDPVPNVIVLSAVGQD--KITQRAITLGADYYVVKP 111


>pir||E75450 DNA-binding response regulator - Deinococcus radiodurans  (strain
           R1) >gi|6458715|gb|AAF10563.1|AE001951_3 (AE001951)
           DNA-binding response regulator [Deinococcus radiodurans]
           Length = 239
           
 Score = 70.2 bits (169), Expect = 3e-11
 Identities = 51/173 (29%), Positives = 83/173 (47%), Gaps = 18/173 (10%)

Query: 6   RKIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPR 65
           R I +L+VDD   +RK  ++++  + +L V GEA  G EA+   +   PDV+ +DV MP 
Sbjct: 24  RPITLLLVDDHPVVRKGTRELLEGETDLRVVGEAGSGEEALAQARSLTPDVILMDVSMPG 83

Query: 66  MNGLDALRVIMKKYPVPVIMISALTQEGAEATIKA-LEYGAIDFIPKPSS---------S 115
           MNG++A + I  K   P + +  LT    +A + A LE GA  ++ K +S         +
Sbjct: 84  MNGIEATKAI--KAEQPSVGVLVLTSYDDDAYVFALLEAGAAGYLLKNASEDDLLGAVRA 141

Query: 116 ISINMRELKDEIIAKIKEAAKV------PRRFLELRRIRLLRVQKAKKVKPSV 162
           ++     L   I  K+ E   V      P   L  R + +LRV  + +    +
Sbjct: 142 VAAGESALHPSIARKVLERFSVASTPTPPEDDLSPRELEVLRVAASGRTNKEI 194


>sp|P13800|DEGU_BACSU TRANSCRIPTIONAL REGULATORY PROTEIN DEGU (PROTEASE PRODUCTION
           ENHANCER PROTEIN) >gi|72614|pir||RGBSXD extracellular
           proteinase response regulator degU - Bacillus subtilis
           >gi|143089|gb|AAA22545.1| (M21658) iep protein [Bacillus
           subtilis] >gi|143499|gb|AAA22733.1| (M23558) degU
           protein (gtg start codon) [Bacillus subtilis]
           >gi|143502|gb|AAA22735.1| (M23649) protein kinase
           (put.); putative [Bacillus subtilis]
           >gi|1762330|gb|AAC44938.1| (U56901) transcriptional
           regulator of degradation enzymes [Bacillus subtilis]
           >gi|2636075|emb|CAB15566.1| (Z99122) two-component
           response regulator [Bacillus subtilis]
           Length = 229
           
 Score = 69.9 bits (168), Expect = 4e-11
 Identities = 34/105 (32%), Positives = 63/105 (59%), Gaps = 1/105 (0%)

Query: 7   KIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRM 66
           K+ ++++DD    R+ +K I++ +P  EV  E  DG EA  +V+   PDVV +D+ MP +
Sbjct: 3   KVNIVIIDDHQLFREGVKRILDFEPTFEVVAEGDDGDEAARIVEHYHPDVVIMDINMPNV 62

Query: 67  NGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPK 111
           NG++A + +++ YP   ++I ++  +    T  AL+ GA  ++ K
Sbjct: 63  NGVEATKQLVELYPESKVIILSIHDDENYVT-HALKTGARGYLLK 106


>pdb|1QMP|A Chain A, Phosphorylated Aspartate In The Crystal Structure Of The
           Sporulation Response Regulator, Spo0a
           >gi|6573583|pdb|1QMP|C Chain C, Phosphorylated Aspartate
           In The Crystal Structure Of The Sporulation Response
           Regulator, Spo0a >gi|6573584|pdb|1QMP|D Chain D,
           Phosphorylated Aspartate In The Crystal Structure Of The
           Sporulation Response Regulator, Spo0a
           >gi|6573582|pdb|1QMP|B Chain B, Phosphorylated Aspartate
           In The Crystal Structure Of The Sporulation Response
           Regulator, Spo0a
           Length = 130
           
 Score = 69.9 bits (168), Expect = 4e-11
 Identities = 40/107 (37%), Positives = 67/107 (62%), Gaps = 4/107 (3%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           I+V + DD+  +  +L + I+S P++EV G A +G + ++M+++ RPD++ L + MP ++
Sbjct: 3   IKVCIADDNRELVSLLDEYISSQPDMEVIGTAYNGQDCLQMLEEKRPDILLLXIIMPHLD 62

Query: 68  GLDALRVIMK--KYPVPVIMISALTQEGAEATIKALEYGAIDFIPKP 112
           GL  L  I    ++   VIM++A  QE  + T KA+E GA  FI KP
Sbjct: 63  GLAVLERIRAGFEHQPNVIMLTAFGQE--DVTKKAVELGASYFILKP 107


>emb|CAB64972.1| (AJ012050) VicR protein [Enterococcus faecalis]
           Length = 283
           
 Score = 69.9 bits (168), Expect = 4e-11
 Identities = 42/128 (32%), Positives = 76/128 (58%), Gaps = 11/128 (8%)

Query: 9   RVLVVDDSAFMRKVLK-DIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           ++LVVDD   + +++K +++    E+     A DG EA+E V++  PD++ LD+ +P+M+
Sbjct: 52  KILVVDDEKPISEIVKYNLVKEGYEVFT---AYDGEEALEKVEEVEPDLIILDLMLPKMD 108

Query: 68  GLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDEI 127
           GL+  R + K + +P+IM++A   E  +  +  LE GA D++ KP S+     REL   +
Sbjct: 109 GLEVAREVRKTHDMPIIMVTAKDSEIDK--VLGLELGADDYVTKPFSN-----RELVARV 161

Query: 128 IAKIKEAA 135
            A ++  A
Sbjct: 162 KANLRRGA 169


>sp|P52929|SP0A_BACBR STAGE 0 SPORULATION PROTEIN A >gi|2119860|pir||S60869
           phosphorylation-activated transcription factor Spo0A -
           Bacillus brevis (fragment) >gi|497949|gb|AAA18872.1|
           (U09971) Spo0A [Brevibacillus brevis]
           Length = 212
           
 Score = 69.5 bits (167), Expect = 6e-11
 Identities = 44/109 (40%), Positives = 67/109 (61%), Gaps = 5/109 (4%)

Query: 7   KIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRM 66
           KI VL+ DD+     +L++ I+S  ++ V G A +G E + ++Q+  PDV+ LD+ MP +
Sbjct: 3   KIEVLLADDNREFVSLLEEYISSQYDMNVIGVAYNGNEVVRLLQERVPDVLILDIIMPHL 62

Query: 67  NGLDALRVI--MKKYPVP-VIMISALTQEGAEATIKALEYGAIDFIPKP 112
           +GL  L  I  M+  P P +IM++A  QE  E T KA+E GA  +I KP
Sbjct: 63  DGLAVLEQIQAMRLSPQPKIIMLTAFGQE--EITKKAVELGAAYYILKP 109


>pir||T35199 probable two-component regulator - Streptomyces coelicolor
           >gi|3036890|emb|CAA18523.1| (AL022374) SC5B8.15,
           probable two-component transcriptional reg ulator, len:
           229 aa; similar to many e.g. DEGU_BACSU P13800
           transcriptional regulator (229 aa), fasta scores; opt:
           485 z-score: 582.9 E(): 2.8e-25, 37.1% identity in 221
           aa over lap. Conta>
           Length = 229
           
 Score = 69.5 bits (167), Expect = 6e-11
 Identities = 44/138 (31%), Positives = 73/138 (52%), Gaps = 2/138 (1%)

Query: 6   RKIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPR 65
           R  RV+VVDD   +R+ +  ++   P ++V G A DG EA+ +V +  PDVV +D+ MPR
Sbjct: 8   RPARVVVVDDQTVVREGIVMLLGLLPGVDVVGAAGDGEEAVRVVAELAPDVVLMDLRMPR 67

Query: 66  MNGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKD 125
            +G++A R I  ++P   +++   T    E+   AL  GA  ++ K +    I +R +  
Sbjct: 68  CDGVEATRRIRSEHPGTQVVV-LTTYADDESLFPALHAGARGYLTKDAGGDEI-VRAVHS 125

Query: 126 EIIAKIKEAAKVPRRFLE 143
            +      A  + RR LE
Sbjct: 126 VLSGDAGLAPSIQRRLLE 143


>dbj|BAB07561.1| (AP001520) two-component response regulator [Bacillus halodurans]
           Length = 530
           
 Score = 69.5 bits (167), Expect = 6e-11
 Identities = 39/128 (30%), Positives = 74/128 (57%), Gaps = 5/128 (3%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           I VL+VDD    R+ LK  +   P + + GEA +G +AIE   + +PD++ +D++MP ++
Sbjct: 2   INVLIVDDEQIEREGLKLFLKDRPNIHIVGEASNGRQAIEKALETQPDLMMMDIKMPGVD 61

Query: 68  GLDALRVIMKKYP-VPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDE 126
           G+ A++ I ++ P    IM+SA   +  E   + + YG  +++ KP++   +      D 
Sbjct: 62  GVQAVKEIKQQLPETEFIMVSAF--DTFEYAREVMRYGVKEYLLKPTTKEDV--LTALDR 117

Query: 127 IIAKIKEA 134
           I+ +I++A
Sbjct: 118 IVGEIEQA 125


>sp|P96126|CHEY_TREPA CHEMOTAXIS PROTEIN CHEY >gi|7443016|pir||D71335 probable chemotaxis
           response regulator (cheY) - syphilis spirochete
           >gi|1765976|gb|AAC45558.1| (U61851) chemotaxis protein
           CheY [Treponema pallidum] >gi|3322643|gb|AAC65351.1|
           (AE001215) chemotaxis response regulator (cheY)
           [Treponema pallidum]
           >gi|5565836|gb|AAD45223.1|AF105017_4 (AF105017)
           chemotaxis protein CheY [Treponema pallidum subsp.
           pertenue]
           Length = 144
           
 Score = 69.1 bits (166), Expect = 8e-11
 Identities = 46/111 (41%), Positives = 67/111 (59%), Gaps = 6/111 (5%)

Query: 5   GRKIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRP--DVVTLDVE 62
           G   RVLVVDDS F+ K +  I+ S+   EV   A DG++ +E  +   P  D+VT+D+ 
Sbjct: 22  GAPYRVLVVDDSMFVSKQIGQILTSEG-YEVADTAVDGVDGVEKYKAMSPGVDLVTMDIT 80

Query: 63  MPRMNGLDALRVIMK-KYPVPVIMISALTQEGAEATIKALEYGAIDFIPKP 112
           MP+M+G+ AL  I++      V++ISAL +E  E   KAL  GA ++I KP
Sbjct: 81  MPKMDGITALEKILEFDKNAKVVIISALGKE--ELVKKALLLGAKNYIVKP 129


>gi|11467627 ompR homolog [Guillardia theta] >gi|6136611|sp|O78428|YC27_GUITH
           PROBABLE TRANSCRIPTIONAL REGULATOR YCF27 (OMPR-LIKE
           PROTEIN) >gi|3602952|gb|AAC35613.1| (AF041468) ompR
           homolog [Guillardia theta]
           Length = 254
           
 Score = 69.1 bits (166), Expect = 8e-11
 Identities = 47/130 (36%), Positives = 71/130 (54%), Gaps = 9/130 (6%)

Query: 7   KIRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRM 66
           K +VL+VDD A +RK+L+  ++      V   A DG EA+ +  +  PDVV LD+ MP++
Sbjct: 14  KEKVLIVDDEASIRKILETRLSMIGYFVVT--ASDGEEALNLFHQEMPDVVILDIMMPKL 71

Query: 67  NGLDALRVIMKKYPVPVIMISALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELKDE 126
           +G    + I K   VP+IM++AL       T   LE GA D++ KP S      +EL+  
Sbjct: 72  DGYGVCQEIRKDSDVPIIMLTALGDVADRIT--GLELGADDYVVKPFSP-----KELEAR 124

Query: 127 IIAKIKEAAK 136
           I A ++   K
Sbjct: 125 IRAVLRRTNK 134


>pir||T36543 probable two-component system regulator - Streptomyces coelicolor
           >gi|4753877|emb|CAB42040.1| (AL049754) putative
           two-component system regulator [Streptomyces coelicolor
           A3(2)]
           Length = 248
           
 Score = 69.1 bits (166), Expect = 8e-11
 Identities = 41/105 (39%), Positives = 58/105 (55%), Gaps = 1/105 (0%)

Query: 8   IRVLVVDDSAFMRKVLKDIINSDPELEVCGEARDGIEAIEMVQKCRPDVVTLDVEMPRMN 67
           IR+LVVDD   +R  L  ++ + P +EV GEA DG EA+ +  + RPDVV +D+ MP + 
Sbjct: 19  IRLLVVDDQYLVRTGLATLLRAAPGMEVVGEASDGAEAVVLAARTRPDVVLMDIRMPGLT 78

Query: 68  GLDALRVIMKKYPVPVIMISALTQ-EGAEATIKALEYGAIDFIPK 111
           G+ A   I+ +   P   I  LT  +  E    AL  GA  F+ K
Sbjct: 79  GIQATERILAQAVDPAPRILVLTTFDLDEYVYGALRAGASGFLLK 123


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.320    0.138    0.386 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 128776504
Number of Sequences: 2977
Number of extensions: 5293071
Number of successful extensions: 13959
Number of sequences better than 1.0e-10: 101
Number of HSP's better than  0.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 61
Number of HSP's that attempted gapping in prelim test: 13835
Number of HSP's gapped (non-prelim): 107
length of query: 368
length of database: 189,106,746
effective HSP length: 58
effective length of query: 310
effective length of database: 154,394,500
effective search space: 47862295000
effective search space used: 47862295000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 166 (69.1 bits)