BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1411 (PAB1411) DE:DOLICHOL-P-GLUCOSE SYNTHETASE
(378 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||F75058 dolichol-p-glucose synthetase PAB1411 - Pyrococcus a... 749 0.0
gi|11497940 dolichol-P-glucose synthetase, putative [Archaeoglob... 386 e-106
gi|11497660 dolichol-P-glucose synthetase, putative [Archaeoglob... 374 e-103
pir||B71154 hypothetical protein PH0433 - Pyrococcus horikoshii ... 185 7e-46
gi|11497999 glycosyltransferase, putative [Archaeoglobus fulgidu... 174 1e-42
pir||A75176 dolichyl-phosphate mannose synthase related protein ... 138 1e-31
pir||E69142 mannosyltransferase - Methanobacterium thermoautotro... 136 3e-31
emb|CAC11300.1| (AL445063) conserved hypothetical protein [Therm... 129 7e-29
pir||D71038 hypothetical protein PH1596 - Pyrococcus horikoshii ... 117 2e-25
pir||B75100 glycosyltransferase PAB1587 - Pyrococcus abyssi (str... 117 2e-25
gb|AAG19457.1| (AE005038) glycosyl transferase-like; Gtl [Haloba... 117 2e-25
pir||D69148 dolichyl-phosphate mannose synthase related protein ... 115 9e-25
gb|AAG00234.1|AF283817_1 (AF283817) dolichol phosphate mannose s... 114 2e-24
pir||G70463 dolichol-phosphate mannosyltransferase - Aquifex aeo... 113 3e-24
gi|6753670 dolichol-phosphate (beta-D) mannosyltransferase 1 [Mu... 113 4e-24
gi|4503363 dolichyl-phosphate mannosyltransferase polypeptide 1;... 113 4e-24
gb|AAD30975.1|AF121895_1 (AF121895) dolichol-phosphate-mannose s... 113 5e-24
gb|AAC98797.1| (AF007875) dolichol monophosphate mannose synthas... 110 3e-23
gb|AAD01952.1| (AF033015) unknown [Listeria monocytogenes] 110 3e-23
gb|AAF53817.1| (AE003663) CG10166 gene product [Drosophila melan... 109 4e-23
sp|Q58619|YC22_METJA HYPOTHETICAL PROTEIN MJ1222 >gi|2128734|pir... 104 2e-21
gb|AAC98796.1| (AF007874) dolichol monophosphate mannose synthas... 104 2e-21
pir||T33929 hypothetical protein Y66H1A.2 - Caenorhabditis elega... 102 7e-21
gb|AAG32629.1|AF102883_1 (AF102883) mannose phospho-dolichol syn... 100 4e-20
pir||A71037 hypothetical protein PH1585 - Pyrococcus horikoshii ... 99 1e-19
pir||G75191 dolichol-phosphate mannosyltransferase PAB2307 - Pyr... 98 1e-19
pir||G69148 dolichyl-phosphate mannose synthase related protein ... 96 7e-19
pir||G69047 conserved hypothetical protein MTH136 - Methanobacte... 94 2e-18
pir||T38633 dolichol monophosphate mannose synthase - fission ye... 94 3e-18
pir||D75177 dolichyl-phosphate mannose synthase PAB1971 - Pyroco... 93 4e-18
gb|AAF80640.1|AC069251_33 (AC069251) F2D10.6 [Arabidopsis thaliana] 93 4e-18
pir||S77381 rfbJ protein - Synechocystis sp. (strain PCC 6803) >... 93 6e-18
pir||H71223 probable dolichol-phosphate mannosyltransferase - Py... 91 2e-17
gb|AAB63812.1| (AF009829) unknown [Mycobacterium bovis] 91 2e-17
emb|CAB76989.1| (AL159178) putative glycosyltransferase [Strepto... 91 2e-17
emb|CAB61668.1| (AL133213) putative glycosyl transferase. [Strep... 90 3e-17
gb|AAG19351.1| (AE005030) galactosyltransferase homolog; Gst [Ha... 89 7e-17
pir||F70546 hypothetical protein Rv0539 - Mycobacterium tubercul... 86 7e-16
gb|AAK43334.1| Dolichol-phosphate mannosyltransferase [Sulfolobu... 82 1e-14
emb|CAC15463.1| (AJ294477) putative polyprenol phosphate mannosy... 82 1e-14
pir||S74796 hypothetical protein sll1020 - Synechocystis sp. (st... 81 3e-14
gi|11498189 dolichol-P-glucose synthetase, putative [Archaeoglob... 81 3e-14
pir||D72736 probable dolichol-phosphate-mannosyltransferase APE0... 78 2e-13
gb|AAF79605.1|AC027665_6 (AC027665) F5M15.10 [Arabidopsis thaliana] 77 4e-13
pir||B70945 hypothetical protein Rv2051c - Mycobacterium tubercu... 76 8e-13
sp|Q57964|Y544_METJA HYPOTHETICAL PROTEIN MJ0544 >gi|2127875|pir... 72 1e-11
emb|CAB81849.1| (AL161691) putative glucosyltransferase [Strepto... 72 1e-11
emb|CAB11300.1| (Z98604) hypothetical protein MLCB2052.02 [Mycob... 72 1e-11
gb|AAG18896.1| (AE004992) dolichol-P-glucose synthetase; Dpg [Ha... 71 2e-11
sp|P54856|DPM1_USTMA DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE (DOL... 70 4e-11
pir||T34985 probable sugar transferase - Streptomyces coelicolor... 70 5e-11
gb|AAF72730.1|AF265258_3 (AF265258) dolichyl-phosphate beta-gluc... 69 6e-11
pir||S76171 hypothetical protein - Synechocystis sp. (strain PCC... 69 8e-11
>pir||F75058 dolichol-p-glucose synthetase PAB1411 - Pyrococcus abyssi (strain
Orsay) >gi|5458876|emb|CAB50363.1| (AJ248287)
DOLICHOL-P-GLUCOSE SYNTHETASE [Pyrococcus abyssi]
Length = 378
Score = 749 bits (1913), Expect = 0.0
Identities = 378/378 (100%), Positives = 378/378 (100%)
Query: 1 MRGFCMGVEVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNL 60
MRGFCMGVEVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNL
Sbjct: 1 MRGFCMGVEVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNL 60
Query: 61 GAKVIRQKGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGS 120
GAKVIRQKGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGS
Sbjct: 61 GAKVIRQKGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGS 120
Query: 121 RLKGKIEPGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGM 180
RLKGKIEPGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGM
Sbjct: 121 RLKGKIEPGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGM 180
Query: 181 EFASEMIIEAAKAGLKIAEVPITYHPRIGESKLHSFKDGWRHLRLMLLYSPLYLFLIPGL 240
EFASEMIIEAAKAGLKIAEVPITYHPRIGESKLHSFKDGWRHLRLMLLYSPLYLFLIPGL
Sbjct: 181 EFASEMIIEAAKAGLKIAEVPITYHPRIGESKLHSFKDGWRHLRLMLLYSPLYLFLIPGL 240
Query: 241 FLILIGSVFLIYGSNTEPLRAHLMILGSLLIIVGFQIINFGISGKVYAVKEGFDKPNKIS 300
FLILIGSVFLIYGSNTEPLRAHLMILGSLLIIVGFQIINFGISGKVYAVKEGFDKPNKIS
Sbjct: 241 FLILIGSVFLIYGSNTEPLRAHLMILGSLLIIVGFQIINFGISGKVYAVKEGFDKPNKIS 300
Query: 301 RFFMRYSILEEGLILGTVLFILGFILGLRIFLKWRAIGYGELFEVRSAIIVLTLMALSIQ 360
RFFMRYSILEEGLILGTVLFILGFILGLRIFLKWRAIGYGELFEVRSAIIVLTLMALSIQ
Sbjct: 301 RFFMRYSILEEGLILGTVLFILGFILGLRIFLKWRAIGYGELFEVRSAIIVLTLMALSIQ 360
Query: 361 LIFFSFFISFLMLKDNSK 378
LIFFSFFISFLMLKDNSK
Sbjct: 361 LIFFSFFISFLMLKDNSK 378
>gi|11497940 dolichol-P-glucose synthetase, putative [Archaeoglobus fulgidus]
>gi|7483293|pir||H69290 dolichol-P-glucose synthetase
homolog - Archaeoglobus fulgidus
>gi|2650309|gb|AAB90908.1| (AE001082) dolichol-P-glucose
synthetase, putative [Archaeoglobus fulgidus]
Length = 371
Score = 386 bits (982), Expect = e-106
Identities = 194/368 (52%), Positives = 261/368 (70%), Gaps = 6/368 (1%)
Query: 10 VSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNLGAKVIRQKG 69
++V+LPT NEEKA+E+++ K+ L +GV EIIVVD S D TPEIA LG +VI+
Sbjct: 2 ITVVLPTKNEEKAIEEIV---KKCLV-VGVK-EIIVVDDSTDSTPEIAEKLGCRVIKNV- 55
Query: 70 KGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRLKGKIEPG 129
KGYG+AYLEG K A G IV+MD DG+YDP EIPKL+E + ++ AD VIGSR KGKI PG
Sbjct: 56 KGYGNAYLEGLKHASGDIIVLMDADGTYDPAEIPKLVEPILRDEADVVIGSRFKGKIMPG 115
Query: 130 AMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEFASEMIIE 189
AMPW H+Y+GNPLLTK+ NFLF SD HSGFRAIK+ +L +L LKC GMEFA+E +++
Sbjct: 116 AMPWHHKYLGNPLLTKLTNFLFGTGFSDVHSGFRAIKKSSLSQLDLKCPGMEFATEFVLK 175
Query: 190 AAKAGLKIAEVPITYHPRIGESKLHSFKDGWRHLRLMLLYSPLYLFLIPGLFLILIGSVF 249
+GL++ EVP+TY+PR G+SKL SF+DGWRHLRL+L SP ++FLIP +FL LIG
Sbjct: 176 TTMSGLRLLEVPVTYYPRKGDSKLRSFRDGWRHLRLILATSPGHVFLIPSIFLTLIGVAV 235
Query: 250 LIYGSNTEPLRAHLMILGSLLIIVGFQIINFGISGKVYAVKEGFDKPNKISRFFMRYSIL 309
+ Y EP+R H +ILG+LL ++G Q FG+SGK+Y+ + GF + ++I+ FF RYS +
Sbjct: 236 MTYVLTFEPIRTHTLILGTLLTLIGIQTFFFGVSGKLYSRQIGFRRDDRITSFFSRYSTI 295
Query: 310 EEGLILGTVLFILGFILGLRIFLKWRAIGYGELFEVRSAIIVLTLMALSIQLIFFSFFIS 369
E ++ G + LGF LG RI W A G+G L E AI+ + L+ Q+I S F+S
Sbjct: 296 EGLMLAGLAILALGFYLGYRIVSFWLAKGFGSLDEFNDAILSMLLIFSGFQIILSSLFLS 355
Query: 370 FLMLKDNS 377
+L +++
Sbjct: 356 MFLLNESN 363
>gi|11497660 dolichol-P-glucose synthetase, putative [Archaeoglobus fulgidus]
>gi|7483292|pir||G69254 dolichol-P-glucose synthetase
homolog - Archaeoglobus fulgidus
>gi|2650613|gb|AAB91190.1| (AE001104) dolichol-P-glucose
synthetase, putative [Archaeoglobus fulgidus]
Length = 369
Score = 374 bits (951), Expect = e-103
Identities = 190/374 (50%), Positives = 254/374 (67%), Gaps = 8/374 (2%)
Query: 8 VEVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNLGAKVIRQ 67
++VS++LPT +E+ ++EKV+ +G EIIVVD S D+TPEIA LG KVIR
Sbjct: 1 MKVSIVLPTKDEQNSIEKVV----RDCLSLGFEKEIIVVDDSADRTPEIAEKLGCKVIRG 56
Query: 68 KGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRLKGKIE 127
KGYG A+LEGF+ + G IVM+D DGSYD EIP+L+E + K AD VIGSR KGKI
Sbjct: 57 V-KGYGRAFLEGFRHSSGDIIVMLDADGSYDALEIPRLIEPIVKGEADLVIGSRFKGKIM 115
Query: 128 PGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEFASEMI 187
P AMPW HRY+GNP+LTK+ N LFK K+SD HSG RA+++DAL K+ C GMEFA+E++
Sbjct: 116 PKAMPWHHRYVGNPVLTKLTNLLFKTKLSDVHSGMRALRKDALAKIDPVCPGMEFATELV 175
Query: 188 IEAAKAGLKIAEVPITYHPRIGESKLHSFKDGWRHLRLMLLYSPLYLFLIPGLFLILIGS 247
++AA GL+I EVPITYHPRIG SKL SF+DGWRHLRL+L SP+YLFL+P + LIL+G
Sbjct: 176 LKAAIKGLRIVEVPITYHPRIGFSKLRSFRDGWRHLRLVLAASPIYLFLLPSIILILLGI 235
Query: 248 VFLIYGSNTEPLRAHLMILGSLLIIVGFQIINFGISGKVYAVKEGFDKPNKISRFFMRYS 307
++ +P+R H +I GS L+++G Q FG+SGK+Y + GF + ++ F +YS
Sbjct: 236 ATALFVIVLQPIRTHTLIFGSTLLLLGIQTFFFGVSGKIYLRQIGFGVRDWLTEAFGKYS 295
Query: 308 ILEEGLILGTVLFILGFILGLRIFLKWRAIGYGELFEVRSAIIVLTLMALSIQLIFFSFF 367
+E+ L G L ILG G R+F W G+G L E A++ L L+ Q+ S F
Sbjct: 296 TMEKLLFFGLALLILGTYSGYRVFASWVERGFGSLAEFNQALVSLILIVSGFQIAISSIF 355
Query: 368 ISFLML---KDNSK 378
+S +L KDN+K
Sbjct: 356 LSMFLLKEEKDNNK 369
>pir||B71154 hypothetical protein PH0433 - Pyrococcus horikoshii
>gi|3256836|dbj|BAA29519.1| (AP000002) 304aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 304
Score = 185 bits (465), Expect = 7e-46
Identities = 105/280 (37%), Positives = 167/280 (59%), Gaps = 13/280 (4%)
Query: 9 EVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNLGAKVIRQK 68
+V++++PT NEE+ + VI + K+ +G +++ S D+T EIA+ GAKV+ Q
Sbjct: 9 DVTILIPTKNEEEGIGWVIEEFKK----LGYNNILVIDGHSTDRTREIAKEKGAKVVLQT 64
Query: 69 GKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRLKGKIEP 128
GKG G A E FK+ + +V++D DG+YDPK++ K+LE +R+ A+ VIG+RL+ E
Sbjct: 65 GKGKGQAVAEAFKLIDSEVVVLIDGDGTYDPKDVEKMLEPIRRGIAEHVIGNRLE-NFED 123
Query: 129 GAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEFASEMII 188
GA L+ IGN + + FL+ + V D SG+RA ++ + + LK G E +E+ +
Sbjct: 124 GAFTRLN-LIGNKIFNALFRFLYGVPVYDMLSGYRAFTKELYKSVELKKHGFEVETELTV 182
Query: 189 EAAKAGLKIAEVPITYHPRIGESKLHSFKDGWR----HLRLMLLYSPL-YLFLIPGLFLI 243
E G +IAEVPI Y+ R G++ LH KDGWR + L++ Y+P YL+ + GLFL+
Sbjct: 183 ETVAKGFRIAEVPINYYKRKGKANLHPIKDGWRIGKAIIELLVRYNPAKYLYFLGGLFLL 242
Query: 244 --LIGSVFLIYGSNTEPLRAHLMILGSLLIIVGFQIINFG 281
LI V+++Y L I+ ++L++ G Q I G
Sbjct: 243 LGLITGVYVVYEWFHHVSHDLLAIVVAILVLGGVQFIAVG 282
>gi|11497999 glycosyltransferase, putative [Archaeoglobus fulgidus]
>gi|7445538|pir||C69298 glycosyltransferase homolog -
Archaeoglobus fulgidus >gi|2650247|gb|AAB90850.1|
(AE001078) glycosyltransferase, putative [Archaeoglobus
fulgidus]
Length = 305
Score = 174 bits (437), Expect = 1e-42
Identities = 107/283 (37%), Positives = 167/283 (58%), Gaps = 16/283 (5%)
Query: 8 VEVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVD-KSNDKTPEIARNLGAKVIR 66
++V+V++PT+NEE+A+ +V+ E A+ G + ++V+D S D+T EIAR GA+V+
Sbjct: 1 MDVTVVIPTLNEEEAIGEVV----EGFAKRG--FRVLVIDGNSKDRTREIAREKGAEVVI 54
Query: 67 QKGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRLKGKI 126
Q GKG G A E F++ +V++D DG+Y P+E+ +LLE +++ AD VIG+R
Sbjct: 55 QSGKGKGQAVAEAFEIVDSDILVLVDGDGTYLPEEVYRLLEPIKEGGADHVIGNRF-ASF 113
Query: 127 EPGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEFASEM 186
E GA L+ IGN LL + +++ D SG+RA+K++ + + L G E +E+
Sbjct: 114 EKGAFTRLN-LIGNKLLNMFFRLAYGVELRDILSGYRALKKEVYKSVELTKPGFEVETEL 172
Query: 187 IIEAAKAGLKIAEVPITYHPRIGESKLHSFKDGWR----HLRLMLLYSPL-YLFLIPGLF 241
+E G +I EVPITY R G++KL+ +DG+R LM YSP YL++ +F
Sbjct: 173 TVETLAKGFRIVEVPITYRKRGGKTKLNPLRDGFRIGKTIYELMSRYSPARYLYIFGLIF 232
Query: 242 LI--LIGSVFLIYGSNTEPLRAHLMILGSLLIIVGFQIINFGI 282
+I LI F++Y L IL +L II G Q+I FG+
Sbjct: 233 IIAGLISGAFVVYEWFLRITHYLLAILTALFIITGVQLIMFGL 275
>pir||A75176 dolichyl-phosphate mannose synthase related protein PAB1981 -
Pyrococcus abyssi (strain Orsay)
>gi|5457998|emb|CAB49488.1| (AJ248284)
DOLICHYL-PHOSPHATE MANNOSE SYNTHASE RELATED PROTEIN
[Pyrococcus abyssi]
Length = 211
Score = 138 bits (343), Expect = 1e-31
Identities = 84/197 (42%), Positives = 120/197 (60%), Gaps = 12/197 (6%)
Query: 8 VEVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNLGAKVIR- 66
++VSVI+P NEEK + KV+ +I E + ++ I+V D S D T ++A+ G +VIR
Sbjct: 1 MKVSVIIPAYNEEKRIGKVLAEIPEFVNEV-----IVVDDGSKDNTADVAKRFGVRVIRL 55
Query: 67 QKGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRLKGKI 126
+ +G G A EG K AKG IV MD DG +DPKEIPK++ + K ADFVIG R+ I
Sbjct: 56 PENRGKGAAMREGIKHAKGDIIVFMDADGQHDPKEIPKIIAPIIKGDADFVIGKRV---I 112
Query: 127 EPGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEFASEM 186
+ G P L R + N + T ++ K KV D SGFRAIKR+ L ++ E +E+
Sbjct: 113 KAGKRP-LVRKLSNFITTTLIRAKIKQKVDDTQSGFRAIKREFLP--DIESERYEVETEV 169
Query: 187 IIEAAKAGLKIAEVPIT 203
+I+ AK G +I EVP++
Sbjct: 170 LIKVAKKGARIVEVPVS 186
>pir||E69142 mannosyltransferase - Methanobacterium thermoautotrophicum (strain
Delta H) >gi|2621387|gb|AAB84837.1| (AE000818)
mannosyltransferase [Methanobacterium
thermoautotrophicum]
Length = 221
Score = 136 bits (340), Expect = 3e-31
Identities = 87/223 (39%), Positives = 132/223 (59%), Gaps = 10/223 (4%)
Query: 10 VSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDK-SNDKTPEIARNLGAKVIRQK 68
++ ++P NEEK++ +I +IK EIIVVD S+D+T EIA + G +VI +
Sbjct: 1 MTFLIPAYNEEKSIGPLIDRIKMLCPDS----EIIVVDNNSSDRTSEIATSRGVRVIFEG 56
Query: 69 GKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRLKGKIEP 128
+G +A + F+ + +Y VMMD D +Y P + L+E+L+ E AD V+GSRL G+ E
Sbjct: 57 KQGKANAMVAAFRNTRTEYAVMMDADLTYLPDDSRVLVEVLKAEGADVVLGSRLNGEKED 116
Query: 129 GAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLT---LKCRGMEFASE 185
GA+ ++ +GN +L+ + L+ VSD +G A R A++ + L G E +E
Sbjct: 117 GAISRINT-VGNHILSFTASILYS-PVSDVCTGHWAFNRRAIRHILEEGLNYSGFELEAE 174
Query: 186 MIIEAAKAGLKIAEVPITYHPRIGESKLHSFKDGWRHLRLMLL 228
M + A+AGLKI EVPITY R E KL SF DG++ R ++L
Sbjct: 175 MFSKLARAGLKIVEVPITYRKRSDEPKLSSFTDGFKIFRTLVL 217
>emb|CAC11300.1| (AL445063) conserved hypothetical protein [Thermoplasma
acidophilum]
Length = 225
Score = 129 bits (320), Expect = 7e-29
Identities = 79/216 (36%), Positives = 120/216 (54%), Gaps = 8/216 (3%)
Query: 9 EVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVD-KSNDKTPEIARNLGAKVIRQ 67
+VS ++PT+NEE + VI I+ EIIVVD S D+T EIAR+ GA+VI +
Sbjct: 7 KVSFVIPTINEEGTIGSVIDGIRSEFPNS----EIIVVDTNSTDRTREIARSKGARVIEE 62
Query: 68 KGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRLKGKIE 127
+GYG AY G A G+ IV MD DG+Y + L+E+L + DF+ R+ +
Sbjct: 63 PRRGYGRAYQTGIPAASGEIIVCMDGDGTYPTDVVKPLIELLIADRVDFISCDRITFRTS 122
Query: 128 PGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEFASEMI 187
LH Y+GN +L + LFK+++ D+ SG + + +K+ GM F+ +
Sbjct: 123 KN-YTTLH-YVGNMVLNLTIRILFKVRMVDSQSGMWVFRSEIYRKMKNLGNGMSFSQNIK 180
Query: 188 IEAAKAGLKIAEVPITYHPRIGESKLHSFKDGWRHL 223
IEA + G+ E+PI Y RI + KL ++ DG+ +L
Sbjct: 181 IEAVRHGV-FMEIPIRYGVRITKPKLKTWHDGFHNL 215
>pir||D71038 hypothetical protein PH1596 - Pyrococcus horikoshii
>gi|3258025|dbj|BAA30708.1| (AP000006) 215aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 215
Score = 117 bits (291), Expect = 2e-25
Identities = 77/208 (37%), Positives = 120/208 (57%), Gaps = 14/208 (6%)
Query: 9 EVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNLGAKVIR-Q 67
++SVI+P NEE+ + V+ I + + ++ I+V D S+D T ++A LGA VIR
Sbjct: 6 KISVIIPAYNEERRIGNVLKGIPDFVDEV-----IVVDDGSSDGTSKVAMELGATVIRLN 60
Query: 68 KGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRLKGKIE 127
K G G A EG K++ G IV MD DG ++PKEI +L++ + + AD VIG R+ I
Sbjct: 61 KNSGKGAAMREGLKISTGDIIVFMDADGQHNPKEIYRLVKPIVEGRADLVIGRRI---IT 117
Query: 128 PGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEFASEMI 187
G P + R I N + T+++ + K+ D SGFRAI+R+ + ++ E +E++
Sbjct: 118 RGKRP-MSRKISNFITTRLITLKTRKKILDTQSGFRAIRREFVP--VIESDRYEVETEVL 174
Query: 188 IEAAKAGLKIAEVPIT--YHPRIGESKL 213
I+A K G +I EVPI+ Y G K+
Sbjct: 175 IKAIKKGARILEVPISTRYDVETGHFKM 202
>pir||B75100 glycosyltransferase PAB1587 - Pyrococcus abyssi (strain Orsay)
>gi|5458615|emb|CAB50103.1| (AJ248286)
glycosyltransferase [Pyrococcus abyssi]
Length = 233
Score = 117 bits (291), Expect = 2e-25
Identities = 79/208 (37%), Positives = 115/208 (54%), Gaps = 7/208 (3%)
Query: 10 VSVILPTMNEEKAVEKVIPQIK-ETLAQMGVTYEIIVVD-KSNDKTPEIARNLGAKV--I 65
V V+LP NEE+ + KVI +I + L + G ++V + S D+T EIARN GA V I
Sbjct: 4 VVVLLPAYNEEETIGKVIDEIPVKKLEKEGYKVTVVVANGPSTDRTEEIARNKGAIVYNI 63
Query: 66 RQKGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRLKGK 125
+ GK + Y+VM+D D +Y P+ I +++ L E D VIGSRLKGK
Sbjct: 64 AKGGKARDVKHALSMIDFPYDYLVMLDADYTYPPQYIYDIVKAL--EEYDVVIGSRLKGK 121
Query: 126 IEPGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEFASE 185
IE GAMP +++ +GN L+ I L+ K+SD +G ++ L + + G + +
Sbjct: 122 IEDGAMPKVNK-LGNWGLSLIATILYGKKISDVCTGMWGFRKYVLDSIEIDANGFDLEAN 180
Query: 186 MIIEAAKAGLKIAEVPITYHPRIGESKL 213
+ +EA K G KI EVPI Y R + KL
Sbjct: 181 LYVEAVKKGFKIGEVPINYRKRPNKPKL 208
>gb|AAG19457.1| (AE005038) glycosyl transferase-like; Gtl [Halobacterium sp. NRC-1]
Length = 305
Score = 117 bits (291), Expect = 2e-25
Identities = 86/290 (29%), Positives = 146/290 (49%), Gaps = 28/290 (9%)
Query: 9 EVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNLGAKVIRQK 68
EV ++PT NE + VI + L ++GV + ++V S D T +A GA+V++Q
Sbjct: 7 EVCALVPTRNEAATIADVI----DGLFEVGVGHVLVVDGNSADDTAAVAAEHGAEVVQQS 62
Query: 69 GKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRLKGKIEP 128
G G G A EG + + Y++++D DG+ P + +LL+ L A+ V+G R + P
Sbjct: 63 GDGKGQAVREGVSLIEAAYVLLLDGDGTNPPAQASRLLDPLVAGEAEHVVGDR-TADMRP 121
Query: 129 GAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEFASEMII 188
GAM L++ IGN L+ + + + D SG+RA ++ ++ L G +EM +
Sbjct: 122 GAMSTLNQ-IGNRLINRAFHRIHGEDYGDILSGYRAFTAESFDRMFLSAEGFGIETEMAV 180
Query: 189 EAAKAGLKIAEVPITY--HPRIGESKLHSFKDGWRHLRLMLLYS------PLYLFLIPG- 239
E ++ + VP TY P E+ LH DG R ++ LYS PL+ F G
Sbjct: 181 ECSRHNITTRVVPTTYRARPDDSETNLHPISDGAR--IILTLYSLAKTSNPLFYFGSIGA 238
Query: 240 ----LFLILIGSV---FLIYGSNTEPLRAHLMILGSLLIIVGFQIINFGI 282
L + L G V +L++G + E + ++ + ++ G Q++ FG+
Sbjct: 239 GFGTLGVALAGYVAYDWLLHGVSHEV----IALVAGVSVLFGVQLLMFGL 284
>pir||D69148 dolichyl-phosphate mannose synthase related protein 2 -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2621435|gb|AAB84880.1| (AE000823) dolichyl-phosphate
mannose synthase related protein [Methanobacterium
thermoautotrophicum]
Length = 291
Score = 115 bits (285), Expect = 9e-25
Identities = 79/247 (31%), Positives = 125/247 (49%), Gaps = 14/247 (5%)
Query: 8 VEVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNLGAKVIRQ 67
+ + ++P NEE A+ V+ E + ++ I+V D S D+T +A GA+VIR
Sbjct: 1 MRIVAVIPAFNEEVAIGSVVLLTGEHVDEV-----IVVDDGSADRTAHVAEMAGARVIRH 55
Query: 68 -KGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSR-LKGK 125
+ G G A GF+ A IV +D D ++P EIPKL+E + + AD V GSR L G+
Sbjct: 56 HRNLGKGAALKTGFEAADADVIVTLDADAQHNPAEIPKLVEPILRGEADVVNGSRYLHGR 115
Query: 126 IEPGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEFASE 185
E +R +G +L + N + ++D SGFRA ++ + G SE
Sbjct: 116 DENTPR---YRRVGQKILDRATNISTGLDITDTQSGFRAFSSASIPHFRFRDPGFVVESE 172
Query: 186 MIIEAAKAGLKIAEVPITYHPRIGESKLHSFKDGWRHLRLML----LYSPLYLFLIPGLF 241
M+ +AA+AGL+I EV + + S + G L ++ L PLY F +PGL
Sbjct: 173 MLADAAEAGLRIVEVEVGVRYDVDGSTRNPISHGVSVLLRIIGDLELKRPLYYFTLPGLI 232
Query: 242 LILIGSV 248
+ + G++
Sbjct: 233 IGITGAI 239
>gb|AAG00234.1|AF283817_1 (AF283817) dolichol phosphate mannose synthase [Schistosoma
mansoni]
Length = 237
Score = 114 bits (283), Expect = 2e-24
Identities = 83/216 (38%), Positives = 117/216 (53%), Gaps = 15/216 (6%)
Query: 11 SVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVD-KSNDKTPEIARNLGA-----KV 64
S+ILPT NE++ + + I + + + G YE+I+VD S D T E+A+ L + K+
Sbjct: 5 SIILPTYNEKENLPIITWIIDKVMNKSGFPYELIIVDDNSPDGTGEVAKKLQSILGENKI 64
Query: 65 IRQ--KGK-GYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSR 121
I + GK G G AYL G K AKG +I++MD D S+ PK IP+ +++ ++ D V G+R
Sbjct: 65 ILKPRSGKLGLGSAYLHGLKFAKGDFIIIMDADLSHHPKFIPEFIKLQKQHDYDVVTGTR 124
Query: 122 LKGKIEPGAMPW-LHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKC--R 178
G W L R + + I L + K SD FR K+ LQ L +C R
Sbjct: 125 YAS--NGGVSGWDLKRKLISRTANYIAQVLLRPKASDLTGSFRLYKKAVLQDLVSRCTSR 182
Query: 179 GMEFASEMIIEAAKAGLKIAEVPITYHPRI-GESKL 213
G F EMI+ A+ G KI EV IT+ R GESKL
Sbjct: 183 GYVFQMEMIVLASSLGYKIGEVGITFVDRFYGESKL 218
>pir||G70463 dolichol-phosphate mannosyltransferase - Aquifex aeolicus
>gi|2984166|gb|AAC07699.1| (AE000762) dolichol-phosphate
mannosyltransferase [Aquifex aeolicus]
Length = 322
Score = 113 bits (281), Expect = 3e-24
Identities = 98/300 (32%), Positives = 148/300 (48%), Gaps = 42/300 (14%)
Query: 10 VSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDK-SNDKTPEIARNLG-----AK 63
+SV++P NEE+ + + ++K+ L +G YEII VD S D+TPEI + + K
Sbjct: 2 ISVVIPAYNEEENIPVLYEKLKKVLDSLGEDYEIIFVDDGSTDRTPEILKEIANKDKKVK 61
Query: 64 VIR-QKGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRL 122
VIR ++ G A GF+ AKG I+ MD D DP++IPKLLE + KE D V G R
Sbjct: 62 VIRFRRNYGQTAAIYAGFEHAKGDVIITMDADLQNDPEDIPKLLEKM-KEGYDIVSGWRK 120
Query: 123 KGKIEPGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEF 182
K P+L R + + + I++ + +++ D +A K D + L F
Sbjct: 121 DRK-----DPFLSRKLPSKIANWIISKVTGVELHDYGCTLKAYKADIAKMYRLYGDMHRF 175
Query: 183 ASEMIIEAAKAGLKIAEVPITYHPRI-GESKLHSFKDGWRHLRLML-----------LYS 230
+ A + G KI E+P+ +HPR+ G SK R +R++L +
Sbjct: 176 LPAL---AKRFGAKITEIPVRHHPRLYGRSKYGID----RTIRVILDIFLVKFLNEYITR 228
Query: 231 PLYLFLIPGLFLILIGSVF--------LIYGSNTEPLRAHLMILGSLLIIVGFQIINFGI 282
PLY+F G L +G + L +G N L+ILG LLI+ G Q+I+ GI
Sbjct: 229 PLYVFGGIGFILFTLGFLIGLYLTVLKLFFGENIG--NRPLLILGVLLILSGIQLISTGI 286
>gi|6753670 dolichol-phosphate (beta-D) mannosyltransferase 1 [Mus musculus]
>gi|3073773|dbj|BAA25759.1| (AB004789)
dolichol-phosphate-mannose synthase [Mus musculus]
Length = 260
Score = 113 bits (280), Expect = 4e-24
Identities = 77/216 (35%), Positives = 116/216 (53%), Gaps = 15/216 (6%)
Query: 11 SVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDK-SNDKTPEIARNLGA-----KV 64
SV+LPT NE + + ++ + ++ ++ + YEII++D S D T E+A L ++
Sbjct: 28 SVLLPTYNERENLPLIVWLLVKSFSESAINYEIIIIDDGSPDGTREVAEQLAEIYGPDRI 87
Query: 65 I---RQKGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSR 121
+ R+K G G AY+ G K A G Y+++MD D S+ PK IP+ + ++ D V G+R
Sbjct: 88 LLRPREKKLGLGTAYIHGIKHATGNYVIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTR 147
Query: 122 LKGKIEPGAMPW-LHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKC--R 178
KG G W L R I + I L + SD FR +++ LQKL KC +
Sbjct: 148 YKG--NGGVYGWDLKRKIISRGANFITQILLRPGASDLTGSFRLYRKEVLQKLIEKCVSK 205
Query: 179 GMEFASEMIIEAAKAGLKIAEVPITYHPRI-GESKL 213
G F EMI+ A + I EVPI++ R+ GESKL
Sbjct: 206 GYVFQMEMIVRARQMNYTIGEVPISFVDRVYGESKL 241
>gi|4503363 dolichyl-phosphate mannosyltransferase polypeptide 1; dolichol
monophosphate mannose synthase [Homo sapiens]
>gi|11420524|ref|XP_009467.1| dolichyl-phosphate
mannosyltransferase polypeptide 1 [Homo sapiens]
>gi|3062806|dbj|BAA25646.1| (D86198)
dolichol-phosphate-mannose synthase [Homo sapiens]
>gi|5817251|emb|CAB53749.1| (AL034553) dJ914P20.1
(dolichyl-phosphate mannosyltransferase polypeptide 1,
catalytic subunit) [Homo sapiens]
Length = 260
Score = 113 bits (280), Expect = 4e-24
Identities = 78/216 (36%), Positives = 117/216 (54%), Gaps = 15/216 (6%)
Query: 11 SVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDK-SNDKTPEIARNL----GAKVI 65
SV+LPT NE + + ++ + ++ ++ G+ YEII++D S D T ++A L G+ I
Sbjct: 28 SVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRI 87
Query: 66 ----RQKGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSR 121
R+K G G AY+ G K A G YI++MD D S+ PK IP+ + ++ D V G+R
Sbjct: 88 LLRPREKKLGLGTAYIHGMKHATGNYIIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTR 147
Query: 122 LKGKIEPGAMPW-LHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKC--R 178
KG G W L R I + + L + SD FR +++ L+KL KC +
Sbjct: 148 YKG--NGGVYGWDLKRKIISRGANFLTQILLRPGASDLTGSFRLYRKEVLEKLIEKCVSK 205
Query: 179 GMEFASEMIIEAAKAGLKIAEVPITYHPRI-GESKL 213
G F EMI+ A + I EVPI++ R+ GESKL
Sbjct: 206 GYVFQMEMIVRARQLNYTIGEVPISFVDRVYGESKL 241
>gb|AAD30975.1|AF121895_1 (AF121895) dolichol-phosphate-mannose synthase [Cricetulus griseus]
Length = 266
Score = 113 bits (279), Expect = 5e-24
Identities = 79/216 (36%), Positives = 115/216 (52%), Gaps = 15/216 (6%)
Query: 11 SVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDK-SNDKTPEIARNL----GAKVI 65
SV+LPT NE + + ++ + ++ ++ + YEII++D S D T E+A L G I
Sbjct: 34 SVLLPTYNERENLPLIVWLLVKSFSESSINYEIIIIDDGSPDGTREVAEQLEKIYGPDRI 93
Query: 66 ----RQKGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSR 121
R+K G G AY+ G K A G Y+++MD D S+ PK IP+ + ++ D V G+R
Sbjct: 94 LLRPREKKLGLGTAYIHGIKHATGNYVIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTR 153
Query: 122 LKGKIEPGAMPW-LHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKC--R 178
KG G W L R I + I L + SD FR +++ LQKL KC +
Sbjct: 154 YKG--NGGVYGWDLKRKIISRGANFITQILLRPGASDLTGSFRLYRKEVLQKLIEKCVSK 211
Query: 179 GMEFASEMIIEAAKAGLKIAEVPITYHPRI-GESKL 213
G F EMI+ A + I EVPI++ R+ GESKL
Sbjct: 212 GYVFQMEMIVRARQLNYTIGEVPISFVDRVYGESKL 247
>gb|AAC98797.1| (AF007875) dolichol monophosphate mannose synthase [Homo sapiens]
Length = 253
Score = 110 bits (272), Expect = 3e-23
Identities = 77/219 (35%), Positives = 119/219 (54%), Gaps = 21/219 (9%)
Query: 11 SVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDK-SNDKTPEIARNL----GAKVI 65
SV+LPT NE + + ++ + ++ ++ G+ YEII++D S D T ++A L G+ I
Sbjct: 21 SVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRI 80
Query: 66 ----RQKGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSR 121
R+K G G AY+ G K A G YI++MD D S+ PK IP+ + ++ D G+R
Sbjct: 81 LLRPREKKLGLGTAYIHGMKHATGNYIIIMDADLSHHPKFIPEFIRKKKEGNFDIASGTR 140
Query: 122 LKGKIEPGAMPWLHRYIGNPLLTKILNFLFKIKV----SDAHSGFRAIKRDALQKLTLKC 177
KG G W + ++++ NFL +I + SD FR ++ L+KL KC
Sbjct: 141 YKG--NGGIYGW---DLKRKIISRGANFLTQILLTPGASDLTGSFRLYPKEVLEKLIEKC 195
Query: 178 --RGMEFASEMIIEAAKAGLKIAEVPITYHPRI-GESKL 213
+G F EMI+ A + I EVPI++ R+ GESKL
Sbjct: 196 VSKGYVFQMEMIVRARQLNYTIGEVPISFVDRVYGESKL 234
>gb|AAD01952.1| (AF033015) unknown [Listeria monocytogenes]
Length = 315
Score = 110 bits (272), Expect = 3e-23
Identities = 75/247 (30%), Positives = 124/247 (49%), Gaps = 8/247 (3%)
Query: 9 EVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNLGAKVIRQK 68
+V+V+LP NEE + KVI K+ L + + + S DKT EIA++ GA V ++
Sbjct: 7 KVAVLLPCYNEELTIGKVIDDFKKELPNADI---YVYDNNSKDKTFEIAKDHGAIVRKEM 63
Query: 69 GKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRLKGKIEP 128
+G G+ F Y +M+D D +Y + ++LE+LR + A+ VIG RL
Sbjct: 64 RQGKGNVVRSMFADIDADYYLMVDGDDTYPAEYCHEILEVLRNKEANMVIGDRLSNGTYT 123
Query: 129 GAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEFASEMII 188
GN L+ +N +FK + D +G+R R ++ + + G E +EM I
Sbjct: 124 EENKRNFHDFGNSLVRNTINRIFKSNLRDIMTGYRGFDRYFVKTMPVLSPGFEIETEMSI 183
Query: 189 EAAKAGLKIAEVPITY--HPRIGESKLHSFKDGWRHLRLMLLYSPLYLFLIPGLFLILIG 246
A + + E+ I Y P ESKL++F DG+ ++++ L+ P LF L+
Sbjct: 184 HALENRFLVKEIEIDYRDRPEGSESKLNTFSDGF---KVIMTIVRLFKNSRPFLFFNLLA 240
Query: 247 SVFLIYG 253
S+F++ G
Sbjct: 241 SLFVLVG 247
>gb|AAF53817.1| (AE003663) CG10166 gene product [Drosophila melanogaster]
Length = 241
Score = 109 bits (271), Expect = 4e-23
Identities = 78/223 (34%), Positives = 121/223 (53%), Gaps = 21/223 (9%)
Query: 7 GVEVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDK-SNDKTPEIARNL----- 60
G + S+++PT NE+ + +I I + + G+ YE+IV+D S D T ++A++L
Sbjct: 5 GHKYSILMPTYNEKDNLPIIIWLIVKYMKASGLEYEVIVIDDGSPDGTLDVAKDLQKIYG 64
Query: 61 -GAKVIRQKGK--GYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFV 117
V+R +G G G AY+ G K A G +IV++D D S+ PK IP+ +++ ++ D V
Sbjct: 65 EDKIVLRPRGSKLGLGTAYIHGIKHATGDFIVIIDADLSHHPKFIPEFIKLQQEGNYDIV 124
Query: 118 IGSRLKGKIEPGAMPWLHRYIGNPLLTKILNFLFKI----KVSDAHSGFRAIKRDALQKL 173
G+R G G W + L+++ NFL ++ SD FR K+D L+K
Sbjct: 125 SGTRYAG--NGGVFGWDFK---RKLISRGANFLSQVLLRPNASDLTGSFRLYKKDVLEKC 179
Query: 174 TLKC--RGMEFASEMIIEAAKAGLKIAEVPITYHPRI-GESKL 213
C +G F EM++ A + G IAEVPIT+ RI G SKL
Sbjct: 180 IASCVSKGYVFQMEMLVRARQHGYTIAEVPITFVDRIYGTSKL 222
>sp|Q58619|YC22_METJA HYPOTHETICAL PROTEIN MJ1222 >gi|2128734|pir||E64452 conserved
hypothetical protein MJ1222 - Methanococcus jannaschii
>gi|1591853|gb|AAB99226.1| (U67563) dolichol-P-glucose
synthetase isolog [Methanococcus jannaschii]
Length = 243
Score = 104 bits (256), Expect = 2e-21
Identities = 76/200 (38%), Positives = 106/200 (53%), Gaps = 11/200 (5%)
Query: 9 EVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNLGAKVIRQ- 67
E+ V++P NEEK + + + +K+ G ++V D S DKT EIA+ G V R
Sbjct: 18 EIFVVVPAFNEEKMIGETLKNLKKE----GYKNIVVVDDGSMDKTSEIAKKEGVIVCRHI 73
Query: 68 KGKGYGDAYLEGFKVA---KGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRLKG 124
+G G A G K A K K I+ D DG + PK++ K+++ + E D IGSR+
Sbjct: 74 LNRGLGGALGTGIKCALLYKPKIIITFDADGQHHPKDVEKVVKPVLFEGYDMAIGSRMMD 133
Query: 125 KIEPGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKL--TLKCRGMEF 182
K E MP + R IGN L I + V+D+ SG RA +A +K+ LK E
Sbjct: 134 KNELKNMPLVKR-IGNFGLNFITYLMGGYFVTDSQSGLRAFSYEAAKKIIGDLKSDRYEV 192
Query: 183 ASEMIIEAAKAGLKIAEVPI 202
+SE II A K GLK+ EVPI
Sbjct: 193 SSEFIILAKKHGLKLKEVPI 212
>gb|AAC98796.1| (AF007874) dolichol monophosphate mannose synthase [Caenorhabditis
briggsae]
Length = 242
Score = 104 bits (256), Expect = 2e-21
Identities = 79/218 (36%), Positives = 117/218 (53%), Gaps = 17/218 (7%)
Query: 11 SVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSN-DKTPEIARNLGAKVIRQK- 68
S+ILPT NE++ + I I++ L G++YEII+VD ++ D T ++A+ L + K
Sbjct: 11 SIILPTYNEKENLPICIWLIEKYLK--GISYEIIIVDDASPDGTQDVAKLLEKEYGENKI 68
Query: 69 ------GK-GYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSR 121
GK G G AY G A+G++I++MD D S+ PK IP+++ + +K D V G+R
Sbjct: 69 LIKPRAGKLGLGTAYSHGLSFARGEFIILMDADLSHHPKFIPEMIALQQKYKLDIVTGTR 128
Query: 122 LKGKIEPGAMPW-LHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLK--CR 178
K G W L R + + FL VSD FR K++ L L + +
Sbjct: 129 YKN--GGGVSGWDLKRKTISKGANFLAQFLLNPGVSDLTGSFRLYKKEVLATLIAESVSK 186
Query: 179 GMEFASEMIIEAAKAGLKIAEVPITYHPR-IGESKLHS 215
G F EM+ A K+G +I EVPI++ R GESKL S
Sbjct: 187 GYVFQMEMMFRAKKSGYRIGEVPISFVDRFFGESKLGS 224
>pir||T33929 hypothetical protein Y66H1A.2 - Caenorhabditis elegans
>gi|4226150|gb|AAD12857.1| (AF125462) similar to
glycosyl transferases (Pfam:PF00535, Score=80.8,
E=2.9e-20, N=1); strong similarity to
dolichol-phosphate-mannose synthase [Caenorhabditis
elegans]
Length = 244
Score = 102 bits (252), Expect = 7e-21
Identities = 81/218 (37%), Positives = 115/218 (52%), Gaps = 17/218 (7%)
Query: 11 SVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSN-DKTPEIARNLGAKVIRQK- 68
S+ILPT NE++ + I I+ L + V++E+I+VD ++ D T IA+ L + K
Sbjct: 13 SIILPTYNEKENLPICIWLIENYLKE--VSHEVIIVDDASPDGTQGIAKLLQKEYGDDKI 70
Query: 69 ------GK-GYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSR 121
GK G G AY G A+G++I++MD D S+ PK IP+++ + K D V G+R
Sbjct: 71 LIKPRVGKLGLGTAYSHGLSFARGEFIILMDADLSHHPKFIPEMIALQHKYKLDIVTGTR 130
Query: 122 LKGKIEPGAMPW-LHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLK--CR 178
K G W L R + + FL VSD FR KRD L KL + +
Sbjct: 131 YKD--GGGVSGWDLKRKTISKGANFLAQFLLNPGVSDLTGSFRLYKRDILSKLIAESVSK 188
Query: 179 GMEFASEMIIEAAKAGLKIAEVPITYHPR-IGESKLHS 215
G F EM+ A K+G +I EVPI++ R GESKL S
Sbjct: 189 GYVFQMEMMFRAKKSGYRIGEVPISFVDRFFGESKLGS 226
>gb|AAG32629.1|AF102883_1 (AF102883) mannose phospho-dolichol synthase [Hypocrea jecorina]
Length = 243
Score = 99.8 bits (245), Expect = 4e-20
Identities = 71/215 (33%), Positives = 111/215 (51%), Gaps = 14/215 (6%)
Query: 11 SVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDK-SNDKTPEIARNL------GAK 63
SVILPT NE K + V + T + + +E+I+VD S D T ++A L
Sbjct: 12 SVILPTYNERKNLPIVAWLLNRTFTEHQLDWELIIVDDGSPDGTQDVANQLVKAYAPHVV 71
Query: 64 VIRQKGK-GYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRL 122
+ + GK G G AY+ G + G ++++MD D S+ PK IP+++ + +K D V G+R
Sbjct: 72 LKTRSGKLGLGTAYVHGLQFVTGNFVIIMDADFSHHPKFIPQMIAVQKKGNYDIVTGTRY 131
Query: 123 KGKIEPGAMPW-LHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKL--TLKCRG 179
G G W L R + + + + VSD FR K+ L+K+ + + +G
Sbjct: 132 AG--NGGVFGWDLKRKFVSRGANLFADTVLRPGVSDLTGSFRLYKKSVLEKVISSTESKG 189
Query: 180 MEFASEMIIEAAKAGLKIAEVPITYHPRI-GESKL 213
F EM++ A G +AEVPI++ R+ GESKL
Sbjct: 190 YTFQMEMMVRAKAMGCTVAEVPISFVDRVYGESKL 224
>pir||A71037 hypothetical protein PH1585 - Pyrococcus horikoshii
>gi|3258014|dbj|BAA30697.1| (AP000006) 313aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 313
Score = 98.7 bits (242), Expect = 1e-19
Identities = 69/195 (35%), Positives = 101/195 (51%), Gaps = 10/195 (5%)
Query: 12 VILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNLGAKVIRQK-GK 70
+++P NEEK + V+ + + + I+V D S DKT EIA++ G VI +
Sbjct: 93 IVMPAYNEEKTIGSVLDSLLKVFKPNNI---IVVDDGSKDKTREIAKSKGVHVISHIINR 149
Query: 71 GYGDAYLEGFKVAK---GKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRLKGKIE 127
G G A G A + IV D DG + ++ K+++ + + AD IGSR KG I
Sbjct: 150 GLGGALGTGIYYALMRGAEIIVTFDADGQHLLEDALKVIKPVVEGRADLAIGSRFKGDI- 208
Query: 128 PGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEFASEMI 187
G MP + R IGN +L I V+D+ SG RA R K+ + C G +SE+I
Sbjct: 209 -GQMPLVKR-IGNIVLNTITAVFAMRYVTDSQSGLRAFSRACASKIKITCDGYAVSSEII 266
Query: 188 IEAAKAGLKIAEVPI 202
+EA++ KI EVPI
Sbjct: 267 VEASRGKCKIVEVPI 281
>pir||G75191 dolichol-phosphate mannosyltransferase PAB2307 - Pyrococcus abyssi
(strain Orsay) >gi|5457491|emb|CAB48982.1| (AJ248283)
DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE [Pyrococcus
abyssi]
Length = 362
Score = 98.3 bits (241), Expect = 1e-19
Identities = 108/355 (30%), Positives = 174/355 (48%), Gaps = 30/355 (8%)
Query: 8 VEVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDK-SNDKTPEIARNLGA---- 62
++VSVI+PT NE + +E++ +I + L YEIIVVD S D+T + A+ L +
Sbjct: 12 MKVSVIVPTYNERENLEELFSRIDKALKDYD--YEIIVVDDDSPDETWKKAQELSSVYPV 69
Query: 63 KVIRQ-KGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSR 121
KVIR+ KG A + GFK A G V+MD D + P+ IP+LL+ + KE AD I SR
Sbjct: 70 KVIRRINEKGLSSAVIRGFKEASGDVFVVMDADLQHPPEVIPELLKRI-KEGADLAIASR 128
Query: 122 L--KGKIEPGAMPWLHRYIGNPLLTKILNFLFKIK-VSDAHSGFRAIKRDALQKLTLKCR 178
G++E P + I + L KI+ + D SGF A+KR+ + + L
Sbjct: 129 YVKGGRVE--NWPLYRKLISKGAIMIARVALPKIRSIKDPVSGFFALKRNVVDNVNLNPI 186
Query: 179 GMEFASEMIIEAAKAGLKIAEVPITYHPRI-GESKL--HSFKDGWRHLRLMLLY----SP 231
G + E++I+ + ++ EVP T+ R+ GESKL + + RH+ ++ +
Sbjct: 187 GFKILLEILIKGRYS--RVEEVPFTFGTRLSGESKLKGKTMLNYLRHVYRLMKWEGEIDR 244
Query: 232 LYLFLIPGLFLILIGSVFLIYGSNTEPLRAHLMILGSLLIIVGFQIINFGISGKVYAVKE 291
L F I GL + + FL + +R + +L S +IN I ++ K+
Sbjct: 245 LVKFSIVGLSGVAVNEGFL-WLFVKMGIRKEVAVLPS----TELSVINNFIWNDLWTFKD 299
Query: 292 GFDKPNKISRFFMRYSILEEGLILGTVLFILGFILGLRIFLKWRAIGYGELFEVR 346
K + + RFF + G+ +++ LG+ +L +G G F VR
Sbjct: 300 -LRKGSVLRRFFQFHIAALIGVFAQLLIYWALLFLGVH-YLISNLVGIGASFIVR 352
>pir||G69148 dolichyl-phosphate mannose synthase related protein 1 -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2621438|gb|AAB84883.1| (AE000823) dolichyl-phosphate
mannose synthase related protein [Methanobacterium
thermoautotrophicum]
Length = 248
Score = 96.0 bits (235), Expect = 7e-19
Identities = 75/203 (36%), Positives = 104/203 (50%), Gaps = 15/203 (7%)
Query: 6 MGVEVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNLGAKVI 65
+ + V ++P NEE+ VE V+ + L V I+V D S D+T + GA+VI
Sbjct: 21 VAMRVVTVIPAFNEERTVESVV---RGALEHGDV---ILVDDGSTDRTAALGEEAGARVI 74
Query: 66 RQ-KGKGYGDAYLEGFKVAKG---KYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSR 121
K G G A G + A G IV MD DG +DP IP+L + DF+IGSR
Sbjct: 75 SHPKNLGKGAALKTGIREALGGDYDVIVFMDADGQHDPSLIPELASAVN--GGDFIIGSR 132
Query: 122 LKGKIEPGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIK-RDALQKLTLKCRGM 180
+ +MP LHR + N + T IL +++D+ SGFRAI R A L +
Sbjct: 133 FI-RNNHDSMP-LHRQLSNRITTWILRLATGYRITDSQSGFRAISARYAHLILEIPYDDY 190
Query: 181 EFASEMIIEAAKAGLKIAEVPIT 203
+ SE I E ++ L+IAEVPIT
Sbjct: 191 VYESEAICETSRHRLRIAEVPIT 213
>pir||G69047 conserved hypothetical protein MTH136 - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621176|gb|AAB84642.1| (AE000802) dolichyl-phosphate
mannose synthase [Methanobacterium thermoautotrophicum]
Length = 220
Score = 94.4 bits (231), Expect = 2e-18
Identities = 73/204 (35%), Positives = 103/204 (49%), Gaps = 22/204 (10%)
Query: 9 EVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDK-SNDKTPEIARNLGAK---- 63
+V+V++P NEEK V VI E+L G Y +I VD S D TPEI + ++
Sbjct: 11 DVAVVVPVYNEEKTVAGVI----ESLLDRG--YRVIAVDDGSRDSTPEILAGIASERDGL 64
Query: 64 --VIRQKGKGYGDAYLEGFKVAKGK---YIVMMDPDGSYDPKEIPKLLEILRKEAADFVI 118
+G G A G + A + IV D DG +DP +I ++E L K AD VI
Sbjct: 65 SVYTHVINRGLGTALRTGLRAAVDEGASCIVTFDADGQHDPDDIEGVIEPLLKGEADVVI 124
Query: 119 GSRLKGKIEPGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCR 178
GSR + MP L R +GN L+ + + +VSD+ SG RA A + +K R
Sbjct: 125 GSR-----DFSEMP-LSRSLGNTLMNLLTLLFYGCRVSDSQSGLRAFTARAASVIDIKSR 178
Query: 179 GMEFASEMIIEAAKAGLKIAEVPI 202
G +SE+I E + GL++ EV I
Sbjct: 179 GYGVSSEIIGEIHRNGLRMREVTI 202
>pir||T38633 dolichol monophosphate mannose synthase - fission yeast
(Schizosaccharomyces pombe) >gi|2258414|gb|AAC98795.1|
(AF007873) dolichol monophosphate mannose synthase
[Schizosaccharomyces pombe] >gi|2388967|emb|CAB11700.1|
(Z98979) dolichol-phosphate mannosyltransferase
[Schizosaccharomyces pombe]
Length = 236
Score = 94.0 bits (230), Expect = 3e-18
Identities = 69/216 (31%), Positives = 111/216 (50%), Gaps = 15/216 (6%)
Query: 11 SVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSN-DKTPEIARNL----GAKVI 65
SV+LPT NE K + + I +T Q + +EI+++D ++ D T E+A+ L G I
Sbjct: 5 SVLLPTYNERKNLPIITYLIAKTFDQEKLDWEIVIIDDASPDGTQEVAKELQKIYGEDKI 64
Query: 66 RQKGK----GYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSR 121
K + G G AY+ G K A G ++++MD D S+ PK +P+ +++ ++ D V+G+R
Sbjct: 65 LLKPRSGKLGLGTAYIHGLKFATGDFVIIMDADFSHHPKYLPEFIKLQKEHNYDIVLGTR 124
Query: 122 LKGKIEPGAMPW-LHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKL--TLKCR 178
+ G W L R + + + + VSD FR K+ L+ L + +
Sbjct: 125 YAK--DGGVYGWNLKRKFISRGANLLASTVLGTGVSDVTGSFRLYKKPVLETLMSEVTSK 182
Query: 179 GMEFASEMIIEAAKAGLKIAEVPITYHPRI-GESKL 213
G F E+I A + I EVPI + R+ GESKL
Sbjct: 183 GYVFQMEIIARAREHNYTIGEVPIAFVDRLYGESKL 218
>pir||D75177 dolichyl-phosphate mannose synthase PAB1971 - Pyrococcus abyssi
(strain Orsay) >gi|5458009|emb|CAB49499.1| (AJ248284)
DOLICHYL-PHOSPHATE MANNOSE SYNTHASE [Pyrococcus abyssi]
Length = 287
Score = 93.2 bits (228), Expect = 4e-18
Identities = 62/196 (31%), Positives = 102/196 (51%), Gaps = 10/196 (5%)
Query: 12 VILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNLGAKVIRQK-GK 70
+++P NEEK + V+ + + + I+V D S D+T EIA++ G V+ +
Sbjct: 67 IVMPAYNEEKTIGDVLDSLLRVFPRENI---IVVDDGSRDRTREIAKSKGVHVVSHIINR 123
Query: 71 GYGDAYLEGFKVA--KGKYIVM-MDPDGSYDPKEIPKLLEILRKEAADFVIGSRLKGKIE 127
G G A G + A KG IV+ D DG + ++ ++++ + + D IGSR KG +
Sbjct: 124 GLGGALGTGIRYAVYKGAEIVVTFDADGQHIVEDALRVIKPVAEGKTDLAIGSRFKGNLN 183
Query: 128 PGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEFASEMI 187
MP + R +GN L I +SD SG RA R+ ++ + C G +SE+I
Sbjct: 184 Q--MPLVKR-VGNIALNLITAIFAFRYISDTQSGLRAFSRNCASRVKITCDGYAVSSEII 240
Query: 188 IEAAKAGLKIAEVPIT 203
+EA++ +I E+PIT
Sbjct: 241 VEASRKKCRIVEIPIT 256
>gb|AAF80640.1|AC069251_33 (AC069251) F2D10.6 [Arabidopsis thaliana]
Length = 246
Score = 93.2 bits (228), Expect = 4e-18
Identities = 79/217 (36%), Positives = 109/217 (49%), Gaps = 19/217 (8%)
Query: 11 SVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDK-SNDKTPEIARNL----GAKVI 65
S+I+PT NE + ++ I + L V +EIIVVD S D T EI + L G I
Sbjct: 16 SIIIPTYNERLNIAIIVYLIFKHLRD--VDFEIIVVDDGSPDGTQEIVKQLQQLYGEDRI 73
Query: 66 ----RQKGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSR 121
R K G G AY+ G K A G ++V+MD D S+ PK +P ++ + A V G+R
Sbjct: 74 LLRARAKKLGLGTAYIHGLKHATGDFVVIMDADLSHHPKYLPSFIKKQLETNASIVTGTR 133
Query: 122 -LKGKIEPGAMPW-LHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKC-- 177
+KG G W L R + + + L VSD FR K+ AL+ + C
Sbjct: 134 YVKG---GGVHGWNLMRKLTSRGANVLAQTLLWPGVSDLTGSFRLYKKSALEDVISSCVS 190
Query: 178 RGMEFASEMIIEAAKAGLKIAEVPITYHPRI-GESKL 213
+G F EMI+ A + G I EVPIT+ R+ G SKL
Sbjct: 191 KGYVFQMEMIVRATRKGYHIEEVPITFVDRVFGTSKL 227
>pir||S77381 rfbJ protein - Synechocystis sp. (strain PCC 6803)
>gi|1652563|dbj|BAA17484.1| (D90906) RfbJ protein
[Synechocystis sp.]
Length = 318
Score = 92.8 bits (227), Expect = 6e-18
Identities = 76/291 (26%), Positives = 128/291 (43%), Gaps = 17/291 (5%)
Query: 4 FCMGVEVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNLGAK 63
F ++V++P NE + +V+ ++ L + + + S D T +A+ GA
Sbjct: 5 FSSAYRLAVLVPCRNEALTITQVVTDFRQQLPNAAI---YVYDNCSTDDTATVAQQAGAI 61
Query: 64 VIRQKGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRLK 123
V +K G G+ F + +++D D +Y+ + + +L++ L E D V+G+R
Sbjct: 62 VRYEKQPGKGNVIRRMFADIEADIYILVDGDNTYEAEAVGRLIDRLINEQLDMVVGARRS 121
Query: 124 GKIEPGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEFA 183
+ A + HR GN LL I+ F ++ D SG+R R ++ G E
Sbjct: 122 EVKDKEAYRFGHR-SGNQLLKGIVELQFGARLDDMLSGYRIFSRRFVKCFPAISNGFEIE 180
Query: 184 SEMIIEAAKAGLKIAEVPITY--HPRIGESKLHSFKDGWRHL-RLMLLYSPLYLFLIPGL 240
+E+ I + L AE P+ Y P ESKL++ DG+R L LL FL G+
Sbjct: 181 TELTIHTLELRLPFAEEPVLYQSRPSGSESKLNTISDGFRVLGTSFLLMKETRPFLFFGV 240
Query: 241 FLILIGS---------VFLIYGSNTEPLRAHLMILGSLLIIVGFQIINFGI 282
F L VF + P R +I+ + L+ +GF G+
Sbjct: 241 FFALFSGSAIALMLPVVFTYLETGLVP-RFPTVIIAASLMSLGFVFFTCGL 290
>pir||H71223 probable dolichol-phosphate mannosyltransferase - Pyrococcus
horikoshii >gi|3256436|dbj|BAA29119.1| (AP000001) 353aa
long hypothetical dolichol-phosphate mannosyltransferase
[Pyrococcus horikoshii]
Length = 353
Score = 91.3 bits (223), Expect = 2e-17
Identities = 79/216 (36%), Positives = 110/216 (50%), Gaps = 17/216 (7%)
Query: 8 VEVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDK-SNDKTPEIARNLG----A 62
++VS+I+PT NE +E++ +I L G YEII+VD S DKT E A L
Sbjct: 1 MKVSIIVPTYNERDNLEELFSRISSALK--GYDYEIIIVDDDSPDKTWEKAMELSKLYPV 58
Query: 63 KVIRQKG-KGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSR 121
KVIR+ KG A + GF A G V+MD D + P+ IP LL + K D I SR
Sbjct: 59 KVIRRVNEKGLSSAVIRGFSEASGDVFVVMDADLQHPPEVIPSLLREIEK-GNDIAIASR 117
Query: 122 L--KGKIEPGAMPWLHRYIGNPLLTKILNFLFKIK-VSDAHSGFRAIKRDALQKLTLKCR 178
GK+E P+ R I + L KI + D SGF A+KR ++ + L
Sbjct: 118 YVKGGKVE--NWPFYRRLISRGAIIIGRLALPKIAGIKDPVSGFFALKRSVVEGVKLNPI 175
Query: 179 GMEFASEMIIEAAKAGLKIAEVPITYHPR-IGESKL 213
G + E++I+ + ++ EVP T+ R GESKL
Sbjct: 176 GFKILMEILIKGKYS--RVTEVPFTFSTRKFGESKL 209
>gb|AAB63812.1| (AF009829) unknown [Mycobacterium bovis]
Length = 218
Score = 90.9 bits (222), Expect = 2e-17
Identities = 66/204 (32%), Positives = 105/204 (51%), Gaps = 13/204 (6%)
Query: 7 GVEVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDK-SNDKTPEIARNLGAKVI 65
G V+V+LP +NEE+++ V LA + Y +VVD S D T +A GA+V+
Sbjct: 3 GDAVTVVLPCLNEEESLPAV-------LAAIPAGYRALVVDNNSTDDTATVAARHGAQVV 55
Query: 66 RQKGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRLKGK 125
+ GYG A G A + ++D DGS D ++PKL+ L K AD V G R
Sbjct: 56 VEPRPGYGSAVHAGVLAATTPIVAVIDADGSMDAGDLPKLVAELDK-GADLVTGRR--RP 112
Query: 126 IEPGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEFASE 185
+ PW+ R +G +++ L ++ V D + R +R+AL L + R + E
Sbjct: 113 VAGLHWPWVAR-VGTVVMSWRLRTRHRLPVHDI-APMRVARREALLDLGVVDRRSGYPLE 170
Query: 186 MIIEAAKAGLKIAEVPITYHPRIG 209
+++ AA AG ++ E+ ++Y PR G
Sbjct: 171 LLVRAAAAGWRVVELDVSYGPRTG 194
>emb|CAB76989.1| (AL159178) putative glycosyltransferase [Streptomyces coelicolor
A3(2)]
Length = 242
Score = 90.9 bits (222), Expect = 2e-17
Identities = 69/220 (31%), Positives = 110/220 (49%), Gaps = 13/220 (5%)
Query: 9 EVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDK-SNDKTPEIARNLGAKVIRQ 67
+V V+LP +NE A+ V LA++ + +VVD S D + ++AR+LGA V+ +
Sbjct: 11 DVDVVLPCLNEAGALPWV-------LARIPAGWRALVVDNGSTDGSADLARSLGATVVTE 63
Query: 68 KGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRLKGKIE 127
+G+G A G A + D D S DP + + +R +D V+G R
Sbjct: 64 PRRGFGAACHAGLTAATADVVCFCDCDASLDPGLLTPFVREIRAGTSDLVLGRRRPQ--A 121
Query: 128 PGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEFASEMI 187
GA P +H GN L ++L +++ D RA +R+ L L L R + +M+
Sbjct: 122 RGAWP-VHARAGNLALARMLRRRTGLRLHDL-GPLRAARRERLLALGLTDRRSGYPLQMV 179
Query: 188 IEAAKAGLKIAEVPITYHPRIGESKL-HSFKDGWRHLRLM 226
+ AA AG +IAE + Y PR G SK+ +++ W +R M
Sbjct: 180 VRAADAGWRIAEHDVPYLPRTGASKVTGTWRGTWHAVRDM 219
>emb|CAB61668.1| (AL133213) putative glycosyl transferase. [Streptomyces coelicolor
A3(2)]
Length = 302
Score = 90.5 bits (221), Expect = 3e-17
Identities = 71/223 (31%), Positives = 117/223 (51%), Gaps = 35/223 (15%)
Query: 12 VILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNLGA-----KVIR 66
VI+PT NE + ++ ++ +++E + + V ++ D S D T ++A L A +V+
Sbjct: 25 VIIPTYNEAENIKAIVTRVREAVPEAHV---LVADDNSPDGTGKLADELAAADDHVQVMH 81
Query: 67 QKGK-GYGDAYLEGFKVAKGK---YIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRL 122
+KGK G G AYL GF+ ++ MD DGS+ P+E+P+LL L+ AD V+GSR
Sbjct: 82 RKGKEGLGAAYLAGFRWGLEHGYGVLIEMDADGSHQPEELPRLLTALK--GADLVLGSRW 139
Query: 123 KGKIEPGAMPWLHRYIGNPLLTKILN--------FLFKIKVSDAHSGFRAIKRDALQKLT 174
PG R + P +I++ + + D G+RA +R+ L+ L
Sbjct: 140 ----VPGG-----RVVNWPKSREIISRGGSMYSRIALDLPLRDITGGYRAFRRETLEGLG 190
Query: 175 LK---CRGMEFASEMIIEAAKAGLKIAEVPITYHPR-IGESKL 213
L+ +G F ++ A KAG + EVPIT+ R +G+SK+
Sbjct: 191 LEEVASQGYCFQVDLARRAIKAGYHVVEVPITFVERELGDSKM 233
>gb|AAG19351.1| (AE005030) galactosyltransferase homolog; Gst [Halobacterium sp.
NRC-1]
Length = 229
Score = 89.3 bits (218), Expect = 7e-17
Identities = 63/211 (29%), Positives = 100/211 (46%), Gaps = 8/211 (3%)
Query: 9 EVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNLGAKVIRQK 68
+V+V + T NE A++ V+ I + ++ VD S+D+TPEIAR GA VI Q+
Sbjct: 10 DVTVAMGTYNEAAAIDTVLTDIADATDDRA---RVVCVDGSSDRTPEIAREHGATVIEQE 66
Query: 69 GKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRLKGKIEP 128
+GYG A A ++ D D +Y + IP L + E D V G RL +
Sbjct: 67 PQGYGVAVAAALDAADTPVVITTDCDNTYPMERIPAFLARI-NEGYDVVSGDRLYWGAD- 124
Query: 129 GAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEFASEMII 188
MP +R +GN I + L +V D +G RA + + + + ++E++I
Sbjct: 125 -TMPAFNR-LGNAAFAAITSLLVGERVHDTTTGMRAYRAPVIDAIDW-TQNTGLSAELLI 181
Query: 189 EAAKAGLKIAEVPITYHPRIGESKLHSFKDG 219
+ E PI Y R+G++KL + G
Sbjct: 182 RPLCRNYDVIEEPIGYADRLGDTKLDPLEGG 212
>pir||F70546 hypothetical protein Rv0539 - Mycobacterium tuberculosis (strain
H37RV) >gi|2114001|emb|CAB08973.1| (Z95558) hypothetical
protein Rv0539 [Mycobacterium tuberculosis]
Length = 210
Score = 85.8 bits (209), Expect = 7e-16
Identities = 63/198 (31%), Positives = 101/198 (50%), Gaps = 13/198 (6%)
Query: 13 ILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDK-SNDKTPEIARNLGAKVIRQKGKG 71
+LP +NEE+++ V LA + Y +VVD S D T +A GA+V+ + G
Sbjct: 1 MLPCLNEEESLPAV-------LAAIPAGYRALVVDNNSTDDTATVAARHGAQVVVEPRPG 53
Query: 72 YGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRLKGKIEPGAM 131
YG A G A + ++D DGS D ++PKL+ L K AD V G R +
Sbjct: 54 YGSAVHAGVLAATTPIVAVIDADGSMDAGDLPKLVAELDK-GADLVTGRR--RPVAGLHW 110
Query: 132 PWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEFASEMIIEAA 191
PW+ R +G +++ L ++ V D + R +R+AL L + R + E+++ AA
Sbjct: 111 PWVAR-VGTVVMSWRLRTRHRLPVHDI-APMRVARREALLDLGVVDRRSGYPLELLVRAA 168
Query: 192 KAGLKIAEVPITYHPRIG 209
AG ++ E+ ++Y PR G
Sbjct: 169 AAGWRVVELDVSYGPRTG 186
>gb|AAK43334.1| Dolichol-phosphate mannosyltransferase [Sulfolobus solfataricus]
Length = 255
Score = 81.5 bits (198), Expect = 1e-14
Identities = 72/227 (31%), Positives = 108/227 (46%), Gaps = 23/227 (10%)
Query: 3 GFCMGVEVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNLGA 62
G C+ S+++PT NE + K++ +I + +IV D S D T I + L
Sbjct: 19 GRCVMGNFSIVIPTYNERDNIVKLVEEINRIVPYNSRI--LIVDDNSPDGTALILQELNI 76
Query: 63 K----VIRQKGKGYGDAYLEGFKVA---KGKYIVMMDPDGSYDPKEIPKLLEILRKEAAD 115
+IR +G G A G A + +IV MD D S++PK +P++++I E D
Sbjct: 77 HNLTVLIRHNERGLGSALRYGISKAIELESDFIVTMDADFSHNPKYLPEMMKIALNENCD 136
Query: 116 FVIGSRLKGKIEPGAMPWLHRYIGNPLLTKILNFLFKI----KVSDAHSGFRAIKRDALQ 171
VIGSR I G W + +++K N+LFK+ + D S +R R A
Sbjct: 137 LVIGSRY--VIGGGIENW---SLSRRIISKGANYLFKLVSHSPIMDNTSNYRIYSRRA-A 190
Query: 172 KLTLKC---RGMEFASEMIIEAAKAGLKIAEVPITYHPR-IGESKLH 214
L L+C G EF I + + LKI E PI + R G+SKL+
Sbjct: 191 LLALECDTTNGYEFQICSIFKIIRNNLKIKEYPIIFVDRKTGKSKLN 237
>emb|CAC15463.1| (AJ294477) putative polyprenol phosphate mannosyl transferase 1
(Ppm1) [Mycobacterium smegmatis]
Length = 265
Score = 81.5 bits (198), Expect = 1e-14
Identities = 66/216 (30%), Positives = 106/216 (48%), Gaps = 19/216 (8%)
Query: 12 VILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNLG------AKVI 65
VI+PT NE + + ++ ++ Q+ + ++V D S D T +A L V+
Sbjct: 26 VIIPTYNERENLPLIVGRVHHACPQVHI---LVVDDGSPDGTGALADELALADPDRVHVM 82
Query: 66 RQKGK-GYGDAYLEGFK--VAKG-KYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSR 121
+ K G G AYL GF + +G +V MD DGS+ P+E+ +LL+ + AD IGSR
Sbjct: 83 HRTSKAGLGAAYLAGFDWGLRRGYSVLVEMDADGSHAPEELSRLLDAV-DAGADLAIGSR 141
Query: 122 LKGKIEPGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKC---R 178
PW R + + FL + + D +G+RA +R+ L+K+ L +
Sbjct: 142 YVPGGTVRNWPW-RRLVLSKTANTYSRFLLGVGIHDITAGYRAYRREVLEKIDLSAVDSK 200
Query: 179 GMEFASEMIIEAAKAGLKIAEVPITYHPR-IGESKL 213
G F ++ A G + EVPIT+ R +G SK+
Sbjct: 201 GYCFQIDLTWRAINNGFSVVEVPITFTERELGVSKM 236
>pir||S74796 hypothetical protein sll1020 - Synechocystis sp. (strain PCC 6803)
>gi|1652021|dbj|BAA16947.1| (D90901) hypothetical
protein [Synechocystis sp.]
Length = 294
Score = 80.8 bits (196), Expect = 3e-14
Identities = 62/268 (23%), Positives = 120/268 (44%), Gaps = 54/268 (20%)
Query: 6 MGVEVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSN--------------- 50
+ +++SVI+P NE + +EK++ +I + + + EI++VD +
Sbjct: 20 ISMKLSVIIPIYNEIQTIEKILKKITTVMPE--IPKEIVMVDDGSKDGTREWLVDTFGDP 77
Query: 51 DKTPEIAR-NLGAK-------------------------------VIRQKGKGYGDAYLE 78
++ P +A NL K + ++ +G G A
Sbjct: 78 EQHPVLANVNLAGKFQCFPLDQSAETNGDRQGNSFVMPKEWEVKVIFHRQNQGKGGALHT 137
Query: 79 GFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRLKGKIEPGAMPWLHRYI 138
F A G +++ D D YDP++ + +++ AD V GSR G P + + H Y+
Sbjct: 138 AFAAATGDVLIIQDADLEYDPEDWGPMWKLIDGGWADVVYGSRFYGN--PHRVLYFHHYL 195
Query: 139 GNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGMEFASEMIIEAAKA--GLK 196
GN L+T +++ + I ++D ++ +R+ L+ L L C F E ++ ++ +
Sbjct: 196 GNKLITSLIDLVCNINLTDIEVCYKMFRREVLEDLRLTCNDFGFEVEFTMKVTRSPKRWR 255
Query: 197 IAEVPITYHPR-IGESKLHSFKDGWRHL 223
I EV + Y+ R E K +++DG + L
Sbjct: 256 IYEVGVAYYGRTFAEGKKINWRDGVKAL 283
>gi|11498189 dolichol-P-glucose synthetase, putative [Archaeoglobus fulgidus]
>gi|7483291|pir||E69322 dolichol-P-glucose synthetase
homolog - Archaeoglobus fulgidus
>gi|2650038|gb|AAB90655.1| (AE001064) dolichol-P-glucose
synthetase, putative [Archaeoglobus fulgidus]
Length = 581
Score = 80.8 bits (196), Expect = 3e-14
Identities = 89/367 (24%), Positives = 158/367 (42%), Gaps = 60/367 (16%)
Query: 8 VEVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVV-DKSNDKTPEIARNLGAKVIR 66
+++S++LP NE K + + ++ + + G +EII+ D S D T IA L A R
Sbjct: 54 MKISIVLPAYNEAKRLRGAVEEVIKAAEKTGYDFEIIIAEDGSKDGTDRIAAELAASNPR 113
Query: 67 QK------GKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGS 120
K G G A + F A G +V MD D + D + +L++ + E DF GS
Sbjct: 114 IKHLHSDERLGRGRALMNAFSKASGDVVVYMDVDLATDLSHLKELVDAIIVEGYDFSTGS 173
Query: 121 RLKGKIEPGAMPWLHRYIGNPLLTKILNFLFKI----KVSDAHSGFRAIKRDALQKL--T 174
RL + + R + ++ NFL ++ K+ D GF+A +RD + L
Sbjct: 174 RLMKESQ------TDRPAKREIASRGYNFLVRLFLGSKLHDHQCGFKAFRRDLILDLGKE 227
Query: 175 LKCRGMEFASEMIIEAAKAGLKIAEVPITYHPRIGESKLHSFKDGWRHLRLMLLYSPLYL 234
+K + +E+++ A K G ++ E+P+ + GE+K+ KD
Sbjct: 228 VKDNHWFWDTEVLVLAQKRGYRVKEIPVRW-KHGGETKVAFGKD---------------- 270
Query: 235 FLIPGLFLILIGSVFLIYGSNTEPLRAHLMILGSLLIIVGFQIINFGISGKVYAVKEGFD 294
L + + ++ + R +L+I S LI + G+ ++ ++
Sbjct: 271 ------ILYMFSQILRMWMDEKKRSRKYLII--STLIALAI----LGVIAVKAGIENVYE 318
Query: 295 KPNKISRFFMRYSILEEGLILGTVLFILGFIL-GLRIFLKWRAIG--YGELFEVRSAIIV 351
I+ FF L+ +L+ L +IL GLR R++G G LF + I
Sbjct: 319 SLISINPFF---------LLTSALLYSLSYILRGLRFDYIMRSLGRERGLLFSTAAVSIS 369
Query: 352 LTLMALS 358
T+ ++
Sbjct: 370 QTVNVIT 376
>pir||D72736 probable dolichol-phosphate-mannosyltransferase APE0426 - Aeropyrum
pernix (strain K1) >gi|5104068|dbj|BAA79384.1|
(AP000059) 373aa long hypothetical
dolichol-phosphate-mannosyltransferase [Aeropyrum
pernix]
Length = 373
Score = 77.6 bits (188), Expect = 2e-13
Identities = 66/221 (29%), Positives = 109/221 (48%), Gaps = 16/221 (7%)
Query: 5 CMGVEVSVILPTMNEEKAVEKVIPQIKETLAQMGVT-YEIIVVDKSN-DKTPEIARNLGA 62
C EVSVI+PT+NE + + +K++L G+ +EI+ VD S+ D T E L
Sbjct: 18 CGEPEVSVIVPTLNERDNIRPLYVGLKKSLEGAGLECFEIVFVDDSSTDGTIEEVERLSR 77
Query: 63 K------VIRQKGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADF 116
++R+ KG A LEG + A+G+ V+MD D + P+ +P L+E + AD
Sbjct: 78 SDPRVRLIVRRGEKGLSRAVLEGLRRARGRVAVVMDADLQHPPETVPLLVEKVAGGEADL 137
Query: 117 VIGSRLK--GKIEPGAMPWLHRYIG-NPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKL 173
+ SR G++E ++ + R I +L L + D SGF A+ + ++
Sbjct: 138 AVASRYAPGGRVEGWSL--VRRIISRGAVLLAWLLIPESRRTRDPVSGFFAVNLERVRPA 195
Query: 174 TLKCRGMEFASEMIIEAAKAGLKIAEVPITYHPRI-GESKL 213
+ RG + E++ A ++ +VP T+ R G SKL
Sbjct: 196 IVSGRGFKILLEILYTNPYA--RVVDVPFTFRGRSRGSSKL 234
>gb|AAF79605.1|AC027665_6 (AC027665) F5M15.10 [Arabidopsis thaliana]
Length = 256
Score = 76.9 bits (186), Expect = 4e-13
Identities = 71/201 (35%), Positives = 96/201 (47%), Gaps = 29/201 (14%)
Query: 39 VTYEIIVVDK-SNDKTPEIARNL----GAKVI----RQKGKGYGDAYLEGFKVAKGKYIV 89
V +EIIVVD S D T EI + L G I R K G G AY+ G K A G ++V
Sbjct: 40 VDFEIIVVDDGSPDGTQEIVKQLQQLYGEDRILLRARAKKLGLGTAYIHGLKHATGDFVV 99
Query: 90 MMDPDGSYDPKEIPKLLEILRKEAADFVIGSR-LKGKIEPGAMPW-LHRYIGNPLLTKIL 147
+MD D S+ PK +P ++ + A V G+R +KG G W L R + + +
Sbjct: 100 IMDADLSHHPKYLPSFIKKQLETNASIVTGTRYVKG---GGVHGWNLMRKLTSRGANVLA 156
Query: 148 NFLFKIKVSDAHSGFRAI------------KRDALQKLTLKC--RGMEFASEMIIEAAKA 193
L VSD FR + K+ AL+ + C +G F EMI+ A +
Sbjct: 157 QTLLWPGVSDLTGSFRIMSDLRTSLFGRLYKKSALEDVISSCVSKGYVFQMEMIVRATRK 216
Query: 194 GLKIAEVPITYHPRI-GESKL 213
G I EVPIT+ R+ G SKL
Sbjct: 217 GYHIEEVPITFVDRVFGTSKL 237
>pir||B70945 hypothetical protein Rv2051c - Mycobacterium tuberculosis (strain
H37RV) >gi|2896788|emb|CAA17265.1| (AL021899)
hypothetical protein Rv2051c [Mycobacterium
tuberculosis]
Length = 874
Score = 75.7 bits (183), Expect = 8e-13
Identities = 67/219 (30%), Positives = 102/219 (45%), Gaps = 21/219 (9%)
Query: 10 VSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSN-DKTPEIARNLG------A 62
V VI+PT NE + +P I L Q ++VVD S+ D T ++A L
Sbjct: 612 VLVIIPTFNEREN----LPVIHRRLTQACPAVHVLVVDDSSPDGTGQLADELAQADPGRT 667
Query: 63 KVIRQKGK-GYGDAYLEGFKVAKGK---YIVMMDPDGSYDPKEIPKLLEILRKEAADFVI 118
V+ + K G G AYL GF + +V MD DGS+ P+++ +LL+ + AD I
Sbjct: 668 HVMHRTAKNGLGAAYLAGFAWGLSREYSVLVEMDADGSHAPEQLQRLLDAV-DAGADLAI 726
Query: 119 GSRLKGKIEPGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTL--- 175
GSR PW R + + I + D +G+RA +R+AL+ + L
Sbjct: 727 GSRYVAGGTVRNWPW-RRLVLSKTANTYSRLALGIGIHDITAGYRAYRREALEAIDLDGV 785
Query: 176 KCRGMEFASEMIIEAAKAGLKIAEVPITYHPR-IGESKL 213
+G F ++ G + EVPIT+ R +G SK+
Sbjct: 786 DSKGYCFQIDLTWRTVSNGFVVTEVPITFTERELGVSKM 824
>sp|Q57964|Y544_METJA HYPOTHETICAL PROTEIN MJ0544 >gi|2127875|pir||H64367
dolichyl-phosphate mannose synthase - Methanococcus
jannaschii >gi|1592295|gb|AAB98538.1| (U67504)
dolichyl-phosphate mannose synthase [Methanococcus
jannaschii]
Length = 229
Score = 72.2 bits (174), Expect = 1e-11
Identities = 68/214 (31%), Positives = 99/214 (45%), Gaps = 35/214 (16%)
Query: 13 ILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNLGAK-------VI 65
I+P NEEK + KV+ +++ ++V D S D T +I K +
Sbjct: 4 IIPAFNEEKNILKVLKDLEKLRVDA-----VVVDDGSKDNTSKIVEEFAKKAKINVYLIR 58
Query: 66 RQKGKGYGDAYLEGFKVA----KGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSR 121
+K +G A +G K A K KYI+ +D D + P +IPKLL+ L AD V G R
Sbjct: 59 NEKNEGKAKAIEKGTKFALSLNKYKYIIYIDGDYQHKPMDIPKLLKKLEDTNADAVFGIR 118
Query: 122 LKGKIEPGAMPWLHRYIGN---PLLTKILNFLFKIK---VSDAHSGFRAIKRDALQKLTL 175
K K P LHR I N +LT + ++ + D GFR IK + L+ +
Sbjct: 119 -KYKHIP-----LHRQISNFFASILTSLAVLIYSKRFYFFRDVQCGFRIIKAEFLKDMKF 172
Query: 176 KCRGMEFASE--MIIEAAKAGLKIAE--VPITYH 205
G +A E + ++ AK G KI E V + YH
Sbjct: 173 ---GDGYAVEHFIALQLAKKGAKIVEEYVSVEYH 203
>emb|CAB81849.1| (AL161691) putative glucosyltransferase [Streptomyces coelicolor
A3(2)]
Length = 345
Score = 72.2 bits (174), Expect = 1e-11
Identities = 42/133 (31%), Positives = 70/133 (52%), Gaps = 7/133 (5%)
Query: 8 VEVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDK-SNDKTPEI--ARNLGAKV 64
V +SV++P NEE + ++ +++ L ++GV +E++ VD S D+T E+ A LG
Sbjct: 13 VVLSVVIPMFNEEDVLPALVTRLRPVLTELGVPHEVVAVDDGSGDRTAELLDAFRLGWPE 72
Query: 65 IR----QKGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGS 120
+R ++ G+ A G A+G Y+V +D D P++IP +L + R E D V G
Sbjct: 73 LRVVALRRNSGHQAALTAGLDRARGAYVVSLDADLQDPPEKIPDMLALARAEGLDIVYGV 132
Query: 121 RLKGKIEPGAMPW 133
R + G W
Sbjct: 133 RADRSSDSGFKRW 145
>emb|CAB11300.1| (Z98604) hypothetical protein MLCB2052.02 [Mycobacterium leprae]
Length = 277
Score = 71.8 bits (173), Expect = 1e-11
Identities = 68/218 (31%), Positives = 100/218 (45%), Gaps = 19/218 (8%)
Query: 10 VSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDKSNDKTPEIARNLG------AK 63
V VI+PT NE + + ++K+ ++ V +IV D S D T E+A L
Sbjct: 19 VLVIIPTFNELENLPVTHGRLKDAYPEIHV---LIVDDGSPDGTGELADELAQVDPGCTH 75
Query: 64 VIRQKGK-GYGDAYLEGFKVAKGK---YIVMMDPDGSYDPKEIPKLLEILRKEAADFVIG 119
V+ + K G G AYL GF + +V MD DGS+ P+++ +LL + AD IG
Sbjct: 76 VMHRTTKDGLGTAYLAGFAWGMSRDYSVLVEMDADGSHAPEQLHRLLGAV-DAGADLAIG 134
Query: 120 SRLKGKIEPGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTL---K 176
SR PW R + K I V D +G+RA +R+ L+ + L
Sbjct: 135 SRYVNGGTVRNWPW-QRLALSKTANKYSRLALGIDVHDITAGYRAYRREVLEAIDLDSVA 193
Query: 177 CRGMEFASEMIIEAAKAGLKIAEVPITYHPR-IGESKL 213
+G F ++ G I EVPIT+ R G SK+
Sbjct: 194 SKGYCFQIDLTWRTVNNGFVIIEVPITFTEREFGLSKM 231
>gb|AAG18896.1| (AE004992) dolichol-P-glucose synthetase; Dpg [Halobacterium sp.
NRC-1]
Length = 614
Score = 71.4 bits (172), Expect = 2e-11
Identities = 65/223 (29%), Positives = 105/223 (46%), Gaps = 16/223 (7%)
Query: 8 VEVSVILPTMNEEKAVEKVIPQIKETLAQM--GVTYEIIVV-DKSNDKTPEIARNLGAK- 63
VEVSV+LP NE ++ + ETLA ++E+IV D +D TP A L A+
Sbjct: 6 VEVSVVLPAYNEADTIDATVHTTVETLAGFLPAGSFEVIVAEDGCDDDTPARADALAAEQ 65
Query: 64 -----VIRQKGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVI 118
+ ++ G G A F VA G +V D D + D + + L+E +R +AD
Sbjct: 66 SAVRHLHSEQRLGRGGALNAAFDVADGDTLVYFDTDLATDMRHLETLVERVRTGSADVAT 125
Query: 119 GSR-LKGKIEPGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLT--L 175
GSR + G E P R I + + + L V D GF+A+ R A + L +
Sbjct: 126 GSRWMPG--ETADRP-AKRGIPSRVFNGAVRTLLGSSVRDHQCGFKALSRSAFEALVDDV 182
Query: 176 KCRGMEFASEMIIEAAKAGLKIAEVPITYHPRIGESKLHSFKD 218
+ +E+++ A + G + E + + P+ G+SK+ +D
Sbjct: 183 ADEHWFWDTELLVRAQRQGFDVEEFAVDWTPK-GDSKVDLVRD 224
>sp|P54856|DPM1_USTMA DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE (DOLICHOL-PHOSPHATE MANNOSE
SYNTHASE) (DOLICHYL-PHOSPHATE
BETA-D-MANNOSYLTRANSFERASE) >gi|7448313|pir||S71642
dolichyl phosphoryl mannose synthase - smut fungus
(Ustilago maydis) >gi|1322289|gb|AAC49401.1| (U54797)
dolichyl phosphoryl mannose synthase [Ustilago maydis]
Length = 294
Score = 70.2 bits (169), Expect = 4e-11
Identities = 68/262 (25%), Positives = 120/262 (44%), Gaps = 30/262 (11%)
Query: 11 SVILPTMNEEKAVEKVIPQIKETLA-----QMGVTYEIIVVDKSNDKTPEIARNLGAK-- 63
SVI+P E + ++ ++ A ++ T IIV D S D + E L ++
Sbjct: 31 SVIVPAFRENLNLRPLVTRLSSAFASQSSSELANTEIIIVDDNSRDGSVETVSALQSEGY 90
Query: 64 ----VIRQKGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIG 119
++ +G A + GF+ A+G+ ++ MD D + P+ +P LL L + + FV+G
Sbjct: 91 NVRIIVATSERGLSSAVVRGFREARGQRMICMDADLQHPPEAVPSLLLALNGQKS-FVLG 149
Query: 120 SRLKGKIEPGAMPWLHRYI---GNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLT-- 174
+R + LHR I G +L + L SD SGF I + +
Sbjct: 150 TRYGVGVSMDKDWPLHRRIISSGARMLARPLT-----SASDPMSGFFGITKHSFHTADHH 204
Query: 175 LKCRGMEFASEMIIEAAKAGLKIAEVPITYHPR-IGESKLHSFKDGWRHLRLMLLYSPLY 233
+ +G + A ++++++ IAEVP ++ R GESKL DG + + LY
Sbjct: 205 INAQGFKIALDLLVKSGVHSTDIAEVPFSFGLRQEGESKL----DGKVMFKYLQQLVELY 260
Query: 234 LF---LIPGLFLILIGSVFLIY 252
F +P +F++++ V +Y
Sbjct: 261 RFRFGTVPIVFVLIVLLVLALY 282
>pir||T34985 probable sugar transferase - Streptomyces coelicolor
>gi|3395543|emb|CAA20162.1| (AL031182) putative sugar
transferase [Streptomyces coelicolor A3(2)]
Length = 478
Score = 69.9 bits (168), Expect = 5e-11
Identities = 72/299 (24%), Positives = 129/299 (43%), Gaps = 39/299 (13%)
Query: 9 EVSVILPTMNEEKAVEKVIPQIKETLAQMGVTYEIIVVDK-SNDKTPEIARNLGAK---- 63
++SV++P NE +E+ ++ L + YEI VD S D+TP++ R LG
Sbjct: 5 QLSVVVPCFNEAAVIERFHSAVENVLGPSNLDYEICYVDDGSTDRTPDLIRQLGFADPRV 64
Query: 64 --VIRQKGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSR 121
V+ + G A L G ++++G+ +V+MD D + P+ IP++LE L D V+ R
Sbjct: 65 RYVVLSRNFGKESAMLAGLRMSRGQAVVLMDADLQHPPELIPRMLE-LHARGYDQVVPRR 123
Query: 122 LKGKIEPGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLTLKCRGME 181
+ A + R + + ++ L +KV D FR + R A+ +
Sbjct: 124 DR------AGDGVVRTLLSRGYYALVRHLMDVKVLDGAGDFRLLSRHAVDTVLSLPETNR 177
Query: 182 FASEMIIEAAKAGLKIAEVPITYHPRIGESKLHSFKDGWRHL-------RLMLLYSPLYL 234
F+ + + + + TY R + S K G R L L PL L
Sbjct: 178 FSKGIF-----SWIGFSTATFTY--RNAQRLAGSSKWGSRRLLNYGIDGLLSFNNRPLRL 230
Query: 235 FLIPGLFLILIGSVF--------LIYGSNTEPLRAHLMILGSLLIIVGFQIINFGISGK 285
+ G + +L+ V+ ++G+ LM+ ++ + G Q+I G+ G+
Sbjct: 231 AIYTGFWCLLVAVVYATWVVIDVAVHGTAVPGYATLLMV---VVALGGVQLITLGVIGE 286
>gb|AAF72730.1|AF265258_3 (AF265258) dolichyl-phosphate beta-glucosyltransferase [Rhodococcus
sp. S9]
Length = 342
Score = 69.5 bits (167), Expect = 6e-11
Identities = 59/204 (28%), Positives = 96/204 (46%), Gaps = 11/204 (5%)
Query: 10 VSVILPTMNEEKAVEKVIPQIKETLAQ-MGVTYEIIVVDK-SNDKTPEIARNL-----GA 62
+ V++P NEE +EK I ++ E L + + I + D SND T +A L G
Sbjct: 22 LEVVIPVYNEEADLEKCIRRLHEHLEERIPFRSRITIADNASNDGTLAVAHRLADEIDGV 81
Query: 63 KVIRQKGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVIGSRL 122
+V KG G A + + + MD D S D + L+ L +D IGSRL
Sbjct: 82 RVHHLDEKGRGRALKAVWLASDADVVAYMDVDLSTDLNALMPLVAPLLSGHSDLAIGSRL 141
Query: 123 KGKIEPGAMPWLHRYIGNPLLTKILNFLFKIKVSDAHSGFRAIKRDALQKLT--LKCRGM 180
+ + R + + IL + + SDA GF+A++ D ++L ++ G
Sbjct: 142 NRSSR--VVRGVKRELISRSYNLILRTSLRARFSDAQCGFKAMRTDVARQLLPLVEDTGW 199
Query: 181 EFASEMIIEAAKAGLKIAEVPITY 204
F +E+++ A K GL+I EVP+ +
Sbjct: 200 FFDTELLVIAEKVGLRIHEVPVDW 223
>pir||S76171 hypothetical protein - Synechocystis sp. (strain PCC 6803)
>gi|1653517|dbj|BAA18430.1| (D90914)
dolichyl-phosphate-mannose synthase [Synechocystis sp.]
Length = 390
Score = 69.1 bits (166), Expect = 8e-11
Identities = 85/340 (25%), Positives = 162/340 (47%), Gaps = 28/340 (8%)
Query: 7 GVEVSVILPTMNEEKAVEKVIPQIKETLA-QMGVTYEIIVVDK-SNDKTPEIARNLG--- 61
G+ +S++LPT NE + ++ ++ + + L + YE+IVVD S D T + A NL
Sbjct: 23 GIFLSLVLPTYNEGENIQAMVTTLVKLLENRWSGQYELIVVDDDSPDLTWQKAFNLSDTY 82
Query: 62 --AKVIRQ-KGKGYGDAYLEGFKVAKGKYIVMMDPDGSYDPKEIPKLLEILRKEAADFVI 118
+VIR+ +G+G A + G++ A+G ++ ++D D + P+ + LL + + AD +
Sbjct: 83 PQLRVIRRTEGRGLSTAVIRGWQEARGNFLGVIDADLQHPPQVLLALLAEMER-GADLAV 141
Query: 119 GSRLKGKIEPGAMPWLHRYIGNPLLTKILNFLFKI--KVSDAHSGFRAIKRDALQKLTLK 176
SR + + R + L L ++ ++SD SGF ++R A+ L
Sbjct: 142 ASRHQSGGGVSQWSLVRRLLSRGAQMLGLLILPEVIGRLSDPMSGFFLVRRQAIADCPLS 201
Query: 177 CRGMEFASEMIIEAAKAGLK-IAEVPITYHP-RIGESKL--HSFKDGWRHL-RLMLLYSP 231
G + E+ A+ ++ +AEV + R G+SK+ + + +HL +L L S
Sbjct: 202 PVGYKILIEV---TARGRIRWLAEVGYVFQERRSGQSKVTWRQYVEYLQHLCKLRLSLSS 258
Query: 232 LYL-FLIPGLFLILIGSVFLIYGSNTEPLRAHLMILGSLLIIVGFQIIN---FGISGKVY 287
+L F GL + + L TEP L + S +I I+N +
Sbjct: 259 RFLQFCAVGLTGVAVDMAILFI--LTEPSLGDLPLSRSKIIAAQLAILNNFFWNDRWTFQ 316
Query: 288 AVKEGFDKPNKISRFFMRYSIL---EEGLILGTVLFILGF 324
+ +G + P+++S+ ++++++ G+ LG + F F
Sbjct: 317 DLTQGQNSPSQVSKRLLKFNLICWAGLGINLGLLNFFFNF 356
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.327 0.146 0.424
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 133789743
Number of Sequences: 2977
Number of extensions: 5768571
Number of successful extensions: 20993
Number of sequences better than 1.0e-10: 53
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 47
Number of HSP's that attempted gapping in prelim test: 20861
Number of HSP's gapped (non-prelim): 57
length of query: 378
length of database: 189,106,746
effective HSP length: 53
effective length of query: 325
effective length of database: 157,386,935
effective search space: 51150753875
effective search space used: 51150753875
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.6 bits)
S2: 166 (69.1 bits)