BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1418 (PAB1418) DE:peptidase
(632 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||E75057 peptidase PAB1418 - Pyrococcus abyssi (strain Orsay)... 1314 0.0
pir||F71174 hypothetical protein PH0594 - Pyrococcus horikoshii ... 1203 0.0
pir||H75007 probable acylaminoacyl-peptidase (EC 3.4.19.1) PAB13... 317 2e-85
pir||C71137 hypothetical protein PH0863 - Pyrococcus horikoshii ... 301 2e-80
pir||F72455 probable acylamino-acid-releasing enzyme APE2290 - A... 286 4e-76
sp|P39839|YUXL_BACSU PROBABLE PEPTIDASE YUXL >gi|7475770|pir||E7... 241 2e-62
pir||F72568 probable acylamino-acid-releasing enzyme APE1832 - A... 238 1e-61
gb|AAK42808.1| Acylaminoacyl-peptidase, putative (apeH-3) [Sulfo... 203 7e-51
pir||E75551 probable acyl-peptide hydrolase - Deinococcus radiod... 196 5e-49
gb|AAG20414.1| (AE005114) acylaminoacyl-peptidase; YuxL [Halobac... 135 1e-30
emb|CAC11802.1| (AL445065) hypothetical protein [Thermoplasma ac... 118 1e-25
pir||B82580 alanyl dipeptidyl peptidase XF2260 [imported] - Xyle... 114 3e-24
gb|AAF20265.1| (AF059279) dipeptidyl-peptidase [Entamoeba dispar] 110 5e-23
gb|AAF20264.1|AF059278_1 (AF059278) dipeptidyl-peptidase [Entamo... 108 2e-22
pir||T09631 probable acylaminoacyl-peptidase (EC 3.4.19.1) - Asp... 106 1e-21
gb|AAD41777.1|AF125190_1 (AF125190) alanyl dipeptidyl peptidase ... 100 6e-20
gb|AAK41653.1| Acylaminoacyl-peptidase, putative (apeH-1) [Sulfo... 99 1e-19
pir||T15945 hypothetical protein F01F1.5 - Caenorhabditis elegan... 99 2e-19
emb|CAB88242.1| (AL353012) putative dipeptidyl peptidase; possib... 96 1e-18
pir||H72474 probable acylamino-acid-releasing enzyme APE2441 - A... 95 2e-18
dbj|BAB09360.1| (AB026661) acyl-peptide hydrolase-like [Arabidop... 93 1e-17
gb|AAK42319.1| Acylaminoacyl-peptidase, putative (apeH-2) [Sulfo... 92 1e-17
pir||S74053 probable acylaminoacyl-peptidase (EC 3.4.19.1) - Sul... 92 1e-17
pir||T35378 probable peptide hydrolase - Streptomyces coelicolor... 92 1e-17
pir||F82858 dipeptidyl-peptidase XF0015 [imported] - Xylella fas... 92 2e-17
pir||S75772 hypothetical protein slr0825 - Synechocystis sp. (st... 91 3e-17
pir||JU0132 acylaminoacyl-peptidase (EC 3.4.19.1) [validated] - ... 87 8e-16
sp|P19205|ACPH_PIG ACYLAMINO-ACID-RELEASING ENZYME (ACYL-PEPTIDE... 87 8e-16
gi|9951917 N-acylaminoacyl-peptide hydrolase; oxidized protein h... 85 2e-15
gb|AAF37321.1|AF141383_1 (AF141383) oxidized protein hydrolase [... 85 2e-15
gi|11431488 N-acylaminoacyl-peptide hydrolase [Homo sapiens] 85 2e-15
gi|6978513 n-acylaminoacyl-peptide hydrolase [Rattus norvegicus]... 85 3e-15
emb|CAA33040.1| (X14915) acyl-peptide hydrolase [Rattus norvegicus] 83 7e-15
gb|AAG18962.1| (AE004997) Vng0409c [Halobacterium sp. NRC-1] 82 3e-14
pir||D72636 probable acylamino-acid-releasing enzyme APE1547 - A... 81 3e-14
gb|AAC35353.1| (AF083393) outer membrane protein adhesin [Capnoc... 80 6e-14
pir||T33751 hypothetical protein R11E3.8 - Caenorhabditis elegan... 80 6e-14
pir||S66261 X-Pro dipeptidyl-peptidase (EC 3.4.14.11) - Flavobac... 77 5e-13
sp|P34422|YL31_CAEEL HYPOTHETICAL 86.0 KDA PROTEIN F44B9.1 IN CH... 77 7e-13
pir||T35975 probable acyl-peptide hydrolase - Streptomyces coeli... 76 9e-13
emb|CAB39035.2| (AL034559) putative acylaminoacyl-peptidase [Pla... 76 1e-12
gb|AAG29766.1|AF221634_1 (AF221634) dipeptidyl peptidase 8 [Homo... 76 1e-12
gb|AAF52407.2| (AE003614) CG11319 gene product [Drosophila melan... 74 6e-12
gb|AAC46184.1| (AF026511) dipeptidyl peptidase IV [Porphyromonas... 73 1e-11
pir||JC5142 X-Pro dipeptidyl-peptidase (EC 3.4.14.11) - Xanthomo... 72 2e-11
gb|AAD52012.1|AF082514_1 (AF082514) Tri r 4 allergen [Trichophyt... 71 4e-11
dbj|BAA28265.1| (AB008194) DPP IV [Porphyromonas gingivalis] 70 6e-11
gb|AAG29769.1|AF221637_1 (AF221637) dipeptidyl peptidase 8 [Homo... 70 9e-11
>pir||E75057 peptidase PAB1418 - Pyrococcus abyssi (strain Orsay)
>gi|5458867|emb|CAB50354.1| (AJ248287) peptidase
[Pyrococcus abyssi]
Length = 632
Score = 1314 bits (3363), Expect = 0.0
Identities = 632/632 (100%), Positives = 632/632 (100%)
Query: 1 MMQLIFGDTVMTSIEWNEKTFTKFAYLSDPRIRGSTIAYVLTKANLDNNKYESTIVLENL 60
MMQLIFGDTVMTSIEWNEKTFTKFAYLSDPRIRGSTIAYVLTKANLDNNKYESTIVLENL
Sbjct: 1 MMQLIFGDTVMTSIEWNEKTFTKFAYLSDPRIRGSTIAYVLTKANLDNNKYESTIVLENL 60
Query: 61 EDGSKRFIEDASMPRISPDGKKIAFMRFNEEKKVAQIWVADMKTLSAKKVLEAKNIRSLE 120
EDGSKRFIEDASMPRISPDGKKIAFMRFNEEKKVAQIWVADMKTLSAKKVLEAKNIRSLE
Sbjct: 61 EDGSKRFIEDASMPRISPDGKKIAFMRFNEEKKVAQIWVADMKTLSAKKVLEAKNIRSLE 120
Query: 121 WNDDSRRLLVIGFKRRDDEDFIFEDDVPAWFDNMGFFDGEKTTFWIVDTEAEEVIEQFEK 180
WNDDSRRLLVIGFKRRDDEDFIFEDDVPAWFDNMGFFDGEKTTFWIVDTEAEEVIEQFEK
Sbjct: 121 WNDDSRRLLVIGFKRRDDEDFIFEDDVPAWFDNMGFFDGEKTTFWIVDTEAEEVIEQFEK 180
Query: 181 PRFSSGVWHGDSIVVNVPYRDTIPRYFKYWNIYLWKDGEEEKLFEKVSFHAIDSDGKNIL 240
PRFSSGVWHGDSIVVNVPYRDTIPRYFKYWNIYLWKDGEEEKLFEKVSFHAIDSDGKNIL
Sbjct: 181 PRFSSGVWHGDSIVVNVPYRDTIPRYFKYWNIYLWKDGEEEKLFEKVSFHAIDSDGKNIL 240
Query: 241 LYGKPEKKYMSEHDKLYIYDGEVKGIMDSIDREAGQAKIKDGKVYFTLYEEGSVNLYLWD 300
LYGKPEKKYMSEHDKLYIYDGEVKGIMDSIDREAGQAKIKDGKVYFTLYEEGSVNLYLWD
Sbjct: 241 LYGKPEKKYMSEHDKLYIYDGEVKGIMDSIDREAGQAKIKDGKVYFTLYEEGSVNLYLWD 300
Query: 301 GDIKEIAKGKHWIMGFDVDEKVVYLKETATRLRELYIWDGEERQLTDYNGLIFSKLKTFE 360
GDIKEIAKGKHWIMGFDVDEKVVYLKETATRLRELYIWDGEERQLTDYNGLIFSKLKTFE
Sbjct: 301 GDIKEIAKGKHWIMGFDVDEKVVYLKETATRLRELYIWDGEERQLTDYNGLIFSKLKTFE 360
Query: 361 PKHFKFKSIDLEIDGWYIKPELKEGEKAPVIVFVHGGPKGMYGYYFKYEMQLMASKGYYI 420
PKHFKFKSIDLEIDGWYIKPELKEGEKAPVIVFVHGGPKGMYGYYFKYEMQLMASKGYYI
Sbjct: 361 PKHFKFKSIDLEIDGWYIKPELKEGEKAPVIVFVHGGPKGMYGYYFKYEMQLMASKGYYI 420
Query: 421 VYVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGITGISYGGF 480
VYVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGITGISYGGF
Sbjct: 421 VYVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGITGISYGGF 480
Query: 481 MTNWALTQSDLFKAGISENGISYWLTSYAFSDIGLWFDKEVIGENPLENENFRKLSPLFY 540
MTNWALTQSDLFKAGISENGISYWLTSYAFSDIGLWFDKEVIGENPLENENFRKLSPLFY
Sbjct: 481 MTNWALTQSDLFKAGISENGISYWLTSYAFSDIGLWFDKEVIGENPLENENFRKLSPLFY 540
Query: 541 AKNVKAPLLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFKRGAHGHSIRGSPRHRM 600
AKNVKAPLLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFKRGAHGHSIRGSPRHRM
Sbjct: 541 AKNVKAPLLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFKRGAHGHSIRGSPRHRM 600
Query: 601 KRYKLFMEFFERKLKKYEEGFDVEKILKGENK 632
KRYKLFMEFFERKLKKYEEGFDVEKILKGENK
Sbjct: 601 KRYKLFMEFFERKLKKYEEGFDVEKILKGENK 632
>pir||F71174 hypothetical protein PH0594 - Pyrococcus horikoshii
>gi|3257000|dbj|BAA29683.1| (AP000002) 622aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 622
Score = 1203 bits (3079), Expect = 0.0
Identities = 559/622 (89%), Positives = 603/622 (96%)
Query: 11 MTSIEWNEKTFTKFAYLSDPRIRGSTIAYVLTKANLDNNKYESTIVLENLEDGSKRFIED 70
MTSIEW+EKTFTKFAYLSDPR R + +AYVLTKANL++NKYE+TIV+ENLEDGS++FIED
Sbjct: 1 MTSIEWDEKTFTKFAYLSDPRTRKNLVAYVLTKANLESNKYENTIVIENLEDGSRKFIED 60
Query: 71 ASMPRISPDGKKIAFMRFNEEKKVAQIWVADMKTLSAKKVLEAKNIRSLEWNDDSRRLLV 130
ASMPRISPDGKKIAFMRFNEEKK AQIWVAD+KTLSAKKVLEAKNIRS+EWN DSRRLL
Sbjct: 61 ASMPRISPDGKKIAFMRFNEEKKTAQIWVADLKTLSAKKVLEAKNIRSIEWNQDSRRLLA 120
Query: 131 IGFKRRDDEDFIFEDDVPAWFDNMGFFDGEKTTFWIVDTEAEEVIEQFEKPRFSSGVWHG 190
+GFKRR+DEDFIFEDDVPAWFDNMGFFDGEKTTFW++DTE EEVIEQFEKPRFSSG+WHG
Sbjct: 121 VGFKRREDEDFIFEDDVPAWFDNMGFFDGEKTTFWVIDTEGEEVIEQFEKPRFSSGIWHG 180
Query: 191 DSIVVNVPYRDTIPRYFKYWNIYLWKDGEEEKLFEKVSFHAIDSDGKNILLYGKPEKKYM 250
DSIVV+VP+RD IPRYFKYW+IYLWKDGEEEKLFEKVSF+AIDSDG+ ILLYGKPEKKY+
Sbjct: 181 DSIVVSVPHRDVIPRYFKYWDIYLWKDGEEEKLFEKVSFYAIDSDGERILLYGKPEKKYV 240
Query: 251 SEHDKLYIYDGEVKGIMDSIDREAGQAKIKDGKVYFTLYEEGSVNLYLWDGDIKEIAKGK 310
SEHDK+YIYDGEVKGI+D IDRE QAKI++GKVYFTL+EEGSVNLYLWDG+++EIAKGK
Sbjct: 241 SEHDKIYIYDGEVKGILDDIDREVAQAKIRNGKVYFTLFEEGSVNLYLWDGEVREIAKGK 300
Query: 311 HWIMGFDVDEKVVYLKETATRLRELYIWDGEERQLTDYNGLIFSKLKTFEPKHFKFKSID 370
HWIMGFD DE+++YLKETATR ELY+WDGEERQLTDYNGLIF KLKTFEP+HF+FKSID
Sbjct: 301 HWIMGFDADERLIYLKETATRPAELYLWDGEERQLTDYNGLIFKKLKTFEPRHFRFKSID 360
Query: 371 LEIDGWYIKPELKEGEKAPVIVFVHGGPKGMYGYYFKYEMQLMASKGYYIVYVNPRGSNG 430
LE+DGWYIKPE+KEGEKAPVIVFVHGGPKGMYGYYFKYEMQLMASKGYYIVYVNPRGSNG
Sbjct: 361 LELDGWYIKPEIKEGEKAPVIVFVHGGPKGMYGYYFKYEMQLMASKGYYIVYVNPRGSNG 420
Query: 431 YSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQSD 490
YSEDFALRVLERTGLEDFQDILNGIEEF +LEPQADRER+GITGISYGG+MTNWALTQSD
Sbjct: 421 YSEDFALRVLERTGLEDFQDILNGIEEFLRLEPQADRERIGITGISYGGYMTNWALTQSD 480
Query: 491 LFKAGISENGISYWLTSYAFSDIGLWFDKEVIGENPLENENFRKLSPLFYAKNVKAPLLL 550
LFKAGISENGISYWLTSYAFSDIGLWFDKEVIG+NPLENEN+RKLSPLFYAKNVKAPLLL
Sbjct: 481 LFKAGISENGISYWLTSYAFSDIGLWFDKEVIGDNPLENENYRKLSPLFYAKNVKAPLLL 540
Query: 551 IHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFKRGAHGHSIRGSPRHRMKRYKLFMEFF 610
IHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFK+GAHGHSIRGSPRHRMKRYKLFMEFF
Sbjct: 541 IHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFKKGAHGHSIRGSPRHRMKRYKLFMEFF 600
Query: 611 ERKLKKYEEGFDVEKILKGENK 632
ERKLKKYEEGFDVEKILK E K
Sbjct: 601 ERKLKKYEEGFDVEKILKEEKK 622
>pir||H75007 probable acylaminoacyl-peptidase (EC 3.4.19.1) PAB1300 [similarity]
- Pyrococcus abyssi (strain Orsay)
>gi|5459016|emb|CAB50502.1| (AJ248288)
ACYLAMINO-ACID-RELEASING ENZYME (EC 3.4.19.1)
(ACYL-PEPTIDE HYDROLASE) (APH) (ACYLAMINOACYL-PEPTIDASE)
[Pyrococcus abyssi]
Length = 631
Score = 317 bits (804), Expect = 2e-85
Identities = 211/638 (33%), Positives = 353/638 (55%), Gaps = 53/638 (8%)
Query: 17 NEKTFTKFAYLSDPRIRGSTIAYVLTKANLDNNKYESTIVLENLEDGSK--RFI---EDA 71
+EK KF + + G + + +T+ ++ N Y S+I L DG K RF +DA
Sbjct: 6 SEKDIEKFKLVGNLDASGKKVVFQVTEISIKENDYFSSIYLY---DGRKVRRFTFGRKDA 62
Query: 72 SMPRISPDGKKIAFM-RFNEEKKVAQIWVADMKTLSAKKVLEAK-NIRSLEWNDDSRRLL 129
+ PR SPDG+ IAF + ++E + +++++ + A+ + + K I+ L +++D + +
Sbjct: 63 N-PRFSPDGRLIAFTSKRSKEGRESELYLMPVDGGEARLLAKFKYGIKDLRFSEDGKEIA 121
Query: 130 VIG---FKR--RDDEDFIFEDDVPAWFDNMGFFDGEKTTFWIVDTEAEEVIEQFEKPR-- 182
VI K+ + ED D++P WF+ +G+ G + ++VD E+ + ++ PR
Sbjct: 122 VITPVEVKKVANEKEDVHVIDEIPFWFNGIGWIYGRRNALYLVDVESGK--KRKVSPRNL 179
Query: 183 --FSSGVWHGDSIVVNVPYRDTIPRYFKYWNIYLWKDGEEEKLFEKVSFHAID----SDG 236
S +G ++ R+ P + + +G+ K + +D SDG
Sbjct: 180 DVLSVRFHNGKLYLLAQEDREKKPMISDVYVL----EGKRVKKLTPGKWRILDFVPLSDG 235
Query: 237 KNILLYGKPEKKYMSEHDKLYIY-DGEVKGI----------MDSIDREAGQAKI--KDGK 283
++L ++ + +Y+Y +GE++ + ++S R A +A++ KDG
Sbjct: 236 --LILKANTLERGFATTTSIYLYRNGELRRLFKEDLSAYNSLNSDVRGAQRAELIFKDGW 293
Query: 284 VYFTLYEEGSVNLYL--WDGDIKEIAKGKHWIMGFDVDEKVVYLKETATRLRELY-IWDG 340
+YF + NL+ DG ++ + +G + F V + + + + AT ELY + DG
Sbjct: 294 IYFVATDGPRANLFRVNLDGKVERVIRGDRSVESFSVGDYIAFTAQDATTPTELYALRDG 353
Query: 341 EERQLTDYNGLIFSKLKTFEPKHFKFKSID-LEIDGWYIKP-ELKEGEKAPVIVFVHGGP 398
+E+++TD+N I K +P+HF+ + D EID W +KP + K G K P ++ +HGGP
Sbjct: 354 KEKRITDFNAWI-RDYKLSKPEHFRVTASDGKEIDAWIMKPVDFKPGRKYPAVLEIHGGP 412
Query: 399 KGMYGYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEF 458
K YGY F +E Q++ +KG+ +++ NPRGS+GY E+FA + G D+QD++ ++E
Sbjct: 413 KTAYGYAFMHEFQVLVAKGFVVIFSNPRGSDGYGEEFA-DIRGHYGERDYQDLMEVVDEA 471
Query: 459 FKLEPQADRERVGITGISYGGFMTNWALTQSDLFKAGISENGISYWLTSYAFSDIGLWFD 518
K D ER+G+TG SYGGFMTNW + ++ FKA +++ IS W++ + +DIG +F
Sbjct: 472 LKRFDFIDEERLGVTGGSYGGFMTNWIVGHTNRFKAAVTQRSISNWISFFGTTDIGYYFA 531
Query: 519 KEVIGENPLEN-ENFRKLSPLFYAKNVKAPLLLIHSLEDYRCPLDQSLMFYHVLKDLGKE 577
+ IG +P N E + + SPL YA NV+ PLL+IHS EDYRC L ++L FY LK LGK
Sbjct: 532 PDQIGGDPWSNLEGYWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQFYIALKYLGKT 591
Query: 578 VYIAIFKRGAHGHSIRGSPRHRMKRYKLFMEFFERKLK 615
V +AIF H S G P+HR+KR +L + +FER LK
Sbjct: 592 VELAIFPGENHDLSRSGRPKHRVKRLELIVGWFERWLK 629
>pir||C71137 hypothetical protein PH0863 - Pyrococcus horikoshii
>gi|3257274|dbj|BAA29957.1| (AP000003) 642aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 642
Score = 301 bits (762), Expect = 2e-80
Identities = 201/641 (31%), Positives = 345/641 (53%), Gaps = 57/641 (8%)
Query: 17 NEKTFTKFAYLSDPRIRGSTIAYVLTKANLDNNKYESTIVLEN------LEDGSKRFIED 70
+EK KF + + + + +T+ +L ++ Y S + L + G+K
Sbjct: 16 SEKDLGKFKLVGNVDVFKGKAVFQVTEISLKDDDYFSKLYLYDGKRVKPFTSGNKD---- 71
Query: 71 ASMPRISPDGKKIAFM-RFNEEKKVAQIWVADMKTLSAKKVLEAK-NIRSLEWNDDSRRL 128
S PR SP+GK IAF + ++E K ++++V A+ + + K I++L + +D + +
Sbjct: 72 -SNPRFSPNGKLIAFTSKRDKEGKESELYVIPTDGGEARLLAKFKYGIKNLRFTEDGKSI 130
Query: 129 LV---IGFKRRDDEDFIFEDDVPAWFDNMGFFDGEKTTFWIVDTEAEEVIEQFEKPRFSS 185
V I +++ ++D ++P WF+ +G+ G++ ++VD +E +K R +
Sbjct: 131 AVVTPIDVEKKGNDDVHIIREIPFWFNGVGWIYGKRNVVYLVD------VESGKKKRLTP 184
Query: 186 GVWHGDSIVVN-----VPYRDTIPRYFKYWNIYLWKDGEEEKL----FEKVSFHAIDSDG 236
+ D I + ++ R ++Y+ ++ + KL + + F +D DG
Sbjct: 185 KNLNVDQIRFHNGRLYFTAQEDRERKPLISDLYVLENRKVRKLTPGKWRILDFLPLD-DG 243
Query: 237 KNILLYGKPEKKYMSEHDKLYIYD---GEVKGIMDSIDREA-------------GQAKIK 280
+L E+ + + +Y YD GE+K + +DR A + K
Sbjct: 244 SFVLKANTLERG-IPTNAHIYHYDPKTGELKKLTKDLDRNAYNSLNSDVRGSQRAELVYK 302
Query: 281 DGKVYFTLYEEGSVNLYL--WDGDIKEIAKGKHWIMGFDVDEKVVYLKETATRLRELYIW 338
+G +Y+ + NL+ DG I+ + G + FD+ + + + + A ELYI+
Sbjct: 303 EGWIYYVATDGPRANLFRVNLDGKIERVIGGDRSVESFDIGDYIAFTAQDAVTPTELYIY 362
Query: 339 -DGEERQLTDYNGLIFSKLKTFEPKHFKFKSID-LEIDGWYIKP-ELKEGEKAPVIVFVH 395
DG+E+++TD+N I + +P+HFK K+ D +EID W +KP ++G+K P I+ +H
Sbjct: 363 RDGKEKKVTDFNKWIKGYTLS-KPEHFKVKASDGVEIDAWVMKPVNFRKGKKYPAILEIH 421
Query: 396 GGPKGMYGYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQDILNGI 455
GGPK YGY F +E ++ SKG+ +++ NPRGS+GY E+FA + G D+QD++ +
Sbjct: 422 GGPKTAYGYAFMHEFHVLTSKGFVVIFSNPRGSDGYGEEFA-DIRGHYGERDYQDLMEVV 480
Query: 456 EEFFKLEPQADRERVGITGISYGGFMTNWALTQSDLFKAGISENGISYWLTSYAFSDIGL 515
+E + D ER+G+TG SYGGFMTNW + ++ FKA +++ IS W++ + +DIG
Sbjct: 481 DEALRRFDFIDGERLGVTGGSYGGFMTNWIVGHTNRFKAAVTQRSISNWISFFGTTDIGY 540
Query: 516 WFDKEVIGENPLEN-ENFRKLSPLFYAKNVKAPLLLIHSLEDYRCPLDQSLMFYHVLKDL 574
+F + IG++P N E + + SPL YA NV+ PLL+IHS EDYRC L ++L + LK L
Sbjct: 541 YFAPDQIGKDPWSNLEGYWEKSPLKYAPNVETPLLIIHSTEDYRCWLPEALQLFISLKYL 600
Query: 575 GKEVYIAIFKRGAHGHSIRGSPRHRMKRYKLFMEFFERKLK 615
GK V +AIF H S G P+HR+KR +L + E+ LK
Sbjct: 601 GKRVELAIFPGENHDLSRSGKPKHRVKRLELIAGWMEKWLK 641
>pir||F72455 probable acylamino-acid-releasing enzyme APE2290 - Aeropyrum pernix
(strain K1) >gi|5105991|dbj|BAA81302.1| (AP000064) 572aa
long hypothetical acylamino-acid-releasing enzyme
[Aeropyrum pernix]
Length = 572
Score = 286 bits (725), Expect = 4e-76
Identities = 184/562 (32%), Positives = 301/562 (52%), Gaps = 30/562 (5%)
Query: 73 MPRISPDGKKIAFMR---FNEEKKVAQIWVADMKTLSAKKVLEAKNIRSLEWNDDSRRLL 129
MP SPD K+AF + +K + +++ + + L W ++ +
Sbjct: 1 MPSWSPDASKLAFASRRGSGKGEKGSGLYIVGRGGEPRRVAWFTHGVSELGWASATKVYV 60
Query: 130 VIGF---KRRD-DEDFIFEDDVPAWFDNMGFFDGEKTTFWIVDTEAEEVIE-QFEKPRFS 184
V K RD D D++ D +P WFD+ G G +VD E+ E
Sbjct: 61 VAPVADEKTRDKDGDYVATDRLPLWFDSSGLVAGLADQIHLVDAESGRTSRLTSEDLGVL 120
Query: 185 SGVWHGDSI--VVNVPYRDTIPRYFKYWNIYLWKDGEEEKLFEKVSFHAIDSDGKNILLY 242
+ G+SI V + D + K I GE E + E ++ + + +
Sbjct: 121 TAEPCGNSIYYVTLRRWADPLDTVVKSVPI---SGGEPETVLEGLTVSQLRCINGKLFML 177
Query: 243 GKPEKKYMSEHDKLYIYDGEVK------GIMD-SIDREAGQAKIKDGKVYFTLYEEGSVN 295
+ ++ H KLY+ + K GI+D +I AG G+ + G
Sbjct: 178 AHKREIGLASHSKLYLLEDRGKASCLTCGILDRNIWSIAGGL---GGEPVIVYADRGRSV 234
Query: 296 LYLWDGDIKEIAKGKHWIMGFDVD-EKVVYLKETATRLRELYIWDGEE-RQLTDYNGLIF 353
+ +G ++++ +G ++ D + E+VVY+ + T E+Y + G + +++ N +
Sbjct: 235 IAAVEGRVEDLVRGDMIVVQADSNGEEVVYIASSPTEPPEVYRFKGGDVERVSSINRWVV 294
Query: 354 SKLKTFEPKHFKFKSIDLEIDGWYIKPELKEGEKAPVIVFVHGGPKGMYGYYFKYEMQLM 413
+ + ++P+ + ++ ++GWYI+PE EG K P+I+F+HGGPKGMYGY F EMQL
Sbjct: 295 EEFRLYKPRRVEVEAEGEVVEGWYIEPE-GEGRK-PLILFIHGGPKGMYGYGFYGEMQLF 352
Query: 414 ASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGIT 473
AS+G+ + Y NPRGS+GY E+FA + R G D++ ++ ++ + D ++ +T
Sbjct: 353 ASEGFTVAYANPRGSDGYEEEFA-DIRGRYGDTDYKQLMKFLDAVVE-GSDVDEGKMAVT 410
Query: 474 GISYGGFMTNWALTQSDLFKAGISENGISYWLTSYAFSDIGLWFDKEVIGENPLEN-ENF 532
GISYGG+MTN +T++ F+A +SENGI+ W+ + +DIG WFD + IG PL+N E +
Sbjct: 411 GISYGGYMTNVIVTKTSRFRAAVSENGIADWIADFWAADIGYWFDPDQIGGTPLDNLEEY 470
Query: 533 RKLSPLFYAKNVKAPLLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFKRGAHGHSI 592
K SP F+AKNV P++LIHS+EDYRC +DQ+L + LK GKE ++ +F +G+HGHSI
Sbjct: 471 VKRSPAFHAKNVNTPVMLIHSMEDYRCFIDQALAMHTALKVNGKESFLVVFTKGSHGHSI 530
Query: 593 RGSPRHRMKRYKLFMEFFERKL 614
SPRHR KR +L +++ + KL
Sbjct: 531 LASPRHRRKRLELKLKWIKEKL 552
>sp|P39839|YUXL_BACSU PROBABLE PEPTIDASE YUXL >gi|7475770|pir||E70025 probable
acylaminoacyl-peptidase (EC 3.4.19.1) yuxL - Bacillus
subtilis >gi|2635720|emb|CAB15213.1| (Z99120) similar to
acylaminoacyl-peptidase [Bacillus subtilis]
Length = 657
Score = 241 bits (608), Expect = 2e-62
Identities = 183/650 (28%), Positives = 309/650 (47%), Gaps = 60/650 (9%)
Query: 22 TKFAYLSDPRIR--GSTIAYVLTKANLDNNKYESTI-VLENLEDGSKRFIED---ASMPR 75
T ++DP+ G+ AYV ++ N + + Y S I + E GS + ++ PR
Sbjct: 11 TAIVSVTDPQYAPDGTRAAYVKSQVNQEKDSYTSNIWIYETKTGGSVPWTHGEKRSTDPR 70
Query: 76 ISPDGKKIAFMRFNEEKKVAQIWVADMKTLSAKKVLEAK-NIRSLEWNDDSRRLLV---- 130
SPDG+ +AF+ + E AQ+++ + A+K+ + + W+ D +LV
Sbjct: 71 WSPDGRTLAFIS-DREGDAAQLYIMSTEGGEARKLTDIPYGVSKPLWSPDGESILVTISL 129
Query: 131 -----IGFKRRDDEDFIFEDDVPAWF---DNMGFFDGEKTTFWIVDTEAEEVIE------ 176
I + + ++D +V D G G +V ++ E+ E
Sbjct: 130 GEGESIDDREKTEQDSYEPVEVQGLSYKRDGKGLTRGAYAQLVLVSVKSGEMKELTSHKA 189
Query: 177 QFEKPRFS-SGVWHGDSIVVNVPYRDTIPRYFKYWNIYLWKDGEEEKLFEKVSF--HAID 233
P FS G W S N+ D + + + L ++ + SF +
Sbjct: 190 DHGDPAFSPDGKWLVFS--ANLTETDDASKPHDVYIMSLESGDLKQVTPHRGSFGSSSFS 247
Query: 234 SDGKNILLYGKPEKKYMSEHDKLYIYD---GEVKGIMDSIDREAGQAKIKDGKV------ 284
DG+ + L G ++ + K ++YD G + + + +D A I D +
Sbjct: 248 PDGRYLALLGNEKEYKNATLSKAWLYDIEQGRLTCLTEMLDVHLADALIGDSLIGGAEQR 307
Query: 285 ----------YFTLYEEGSVNLYLW--DGDIKEIAKGKHWIMGFDVDEKVVYLKETAT-- 330
Y ++GS +Y +G + I K +I F + + + T
Sbjct: 308 PIWTKDSQGFYVIGTDQGSTGIYYISIEGLVYPIRLEKEYINSFSLSPDEQHFIASVTKP 367
Query: 331 -RLRELYI--WDGEERQLTDYNGLIFSKLKTFEPKHFKFKSID-LEIDGWYIKPELKEGE 386
R ELY EE+QLT N + P+ ++ + D + ++GW ++P EGE
Sbjct: 368 DRPSELYSIPLGQEEKQLTGANDKFVREHTISIPEEIQYATEDGVMVNGWLMRPAQMEGE 427
Query: 387 KA-PVIVFVHGGPKGMYGYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGL 445
P+I+ +HGGP MYG+ + +E Q++A+KGY +VY+NPRGS+GY ++F V G
Sbjct: 428 TTYPLILNIHGGPHMMYGHTYFHEFQVLAAKGYAVVYINPRGSHGYGQEFVNAVRGDYGG 487
Query: 446 EDFQDILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQSDLFKAGISENGISYWL 505
+D+ D++ ++E K +P D +R+G+TG SYGGFMTNW + Q++ FKA +++ IS W+
Sbjct: 488 KDYDDVMQAVDEAIKRDPHIDPKRLGVTGGSYGGFMTNWIVGQTNRFKAAVTQRSISNWI 547
Query: 506 TSYAFSDIGLWFDKEVIGENPLEN-ENFRKLSPLFYAKNVKAPLLLIHSLEDYRCPLDQS 564
+ + SDIG +F + + E+ E SPL YA NV+ PLL++H D RCP++Q+
Sbjct: 548 SFHGVSDIGYFFTDWQLEHDMFEDTEKLWDRSPLKYAANVETPLLILHGERDDRCPIEQA 607
Query: 565 LMFYHVLKDLGKEVYIAIFKRGAHGHSIRGSPRHRMKRYKLFMEFFERKL 614
+ LK +GKE + F +H S G PR R+KR +F++ L
Sbjct: 608 EQLFIALKKMGKETKLVRFPNASHNLSRTGHPRQRIKRLNYISSWFDQHL 657
>pir||F72568 probable acylamino-acid-releasing enzyme APE1832 - Aeropyrum pernix
(strain K1) >gi|5105522|dbj|BAA80835.1| (AP000062) 659aa
long hypothetical acylamino-acid-releasing enzyme
[Aeropyrum pernix]
Length = 659
Score = 238 bits (602), Expect = 1e-61
Identities = 178/651 (27%), Positives = 316/651 (48%), Gaps = 59/651 (9%)
Query: 23 KFAYLSDPRI--RGSTIAYVLTKANLDNNKYESTIVLENLEDGSKRFIEDASMPRI---S 77
+ ++S+P + G +AY+ TKA+ N Y S I L E+ S R + R S
Sbjct: 15 RLTFVSNPSVSPEGDKVAYLATKADEKENTYRSGIWLA--EEDSYRPLTGGPYDRCPAWS 72
Query: 78 PDGKKIAFMRFNEEKKVAQIWVADMKTLSAKKVLEAKNIR---SLEWNDD-------SRR 127
PDG+ IAF R + + ++A + + + +++ S++W+ SR+
Sbjct: 73 PDGEIIAFSRTVNSNQRKRHYIAIVSPKGGEPQVLHESVSPATSIKWSSQGSMIGYLSRK 132
Query: 128 LLVIGFKRRDDEDFIFEDDVPAWFDNMGFFDGEKTTFWIVDTEAEEVIEQFEKPRFSSGV 187
+K + D + D +P WFD+ G+ ++ EV+ EK + +
Sbjct: 133 PTGREWKPYSERDVLEIDRIPVWFDSEGWVFDRYWGLTVISYPGGEVL--LEKGGVNYNI 190
Query: 188 WH-----GDSIVVNVPYRDTIPRYFKYWNIYLWKDGEEEKLFEKVSFHAI--DSDGKNIL 240
D+ +V D + ++ G E+ L E ++ A+ D G+ I
Sbjct: 191 VDFDFAPDDNTIVYAVSTDMKKPFIHKLVLWDLASGREKTLIEGLTIAAVAFDPRGRYIA 250
Query: 241 LYGKPEKKYMSEHDKLYIYDGEVK-----------GIMDSIDREA-------GQAKIKDG 282
+ K+ + H K+++YD + +++++ +A G +G
Sbjct: 251 VKANDRKRGLFSHYKIFVYDLNSEEFVCLTCDLDLNTLNTVNSDARGPSCLRGMYWDDNG 310
Query: 283 KVYFTLYEEGSVNLYLWD--GDIKEIAK-GKHWIMGFDVD---EKVVYLKETATRLRELY 336
+Y+ ++ G + + G+ + + + F + + + Y+K T ++Y
Sbjct: 311 HLYYGVHNAGRMVVMKSRPLGEAEAVLDPSSATVDDFSISRGGDTIAYVKMGPTSPPDIY 370
Query: 337 IW-DGEERQLTDYNGLIFSKLKTFEPKHFKFKS-IDLEIDGWYIKPELKEGEKA---PVI 391
I+ D E +LTD+N EP + +S + ID W + P GE + P I
Sbjct: 371 IYRDDNEYRLTDHNAWFAESRSLAEPVRLQVQSPLGGSIDAWILLPP-DAGECSGCLPWI 429
Query: 392 VFVHGGPKGMYGYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQDI 451
+++HGGPK YGY F +E Q++AS+G+ ++Y NPRGS+GYSE+FA + R G++D+ ++
Sbjct: 430 LYIHGGPKTSYGYAFIHEFQMLASQGFAVIYSNPRGSDGYSEEFA-DLRGRYGVDDYSEL 488
Query: 452 LNGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQSDLFKAGISENGISYWLTSYAFS 511
+ ++E PQ D +R G+TG SYGG+MTN +T++ FKA +++ S W++ Y S
Sbjct: 489 MKVVDEALSDFPQLDPQRGGVTGGSYGGYMTNVIVTKTRRFKAAVTQRSCSNWISFYGES 548
Query: 512 DIGLWFDKEVI-GENPLEN-ENFRKLSPLFYAKNVKAPLLLIHSLEDYRCPLDQSLMFYH 569
DIG +F E+I + P + E + SPLF +N++ PLL+IHS ED+RCPL ++ +
Sbjct: 549 DIGWYFAPELISAQEPWRDLEKYVDFSPLFSVENIETPLLIIHSTEDFRCPLSGAIQLFT 608
Query: 570 VLKDLGKEVYIAIFKRGAHGHSIRGSPRHRMKRYKLFMEFFERKLKKYEEG 620
LK G E + +F H S G+P+ R+ R + +F+ L + G
Sbjct: 609 ALKLKGVETRLLVFPGENHNLSRSGTPKRRVARLRAIASWFKEHLGSQQRG 659
>gb|AAK42808.1| Acylaminoacyl-peptidase, putative (apeH-3) [Sulfolobus
solfataricus]
Length = 591
Score = 203 bits (510), Expect = 7e-51
Identities = 115/334 (34%), Positives = 178/334 (52%), Gaps = 26/334 (7%)
Query: 290 EEGSVNLY-LWDGDIKEIAKGKHWIMGFDV-DEKVVYLKETATRLRELYIWDGEERQLTD 347
E G+ ++Y + D + ++ G + GFD + ++ Y T E+ +
Sbjct: 274 EGGTSHIYQISDNKVDKVTSGNIMVRGFDYSNSELAYFYSTP-----------EKPVILK 322
Query: 348 YNGLIFS---KLKTFEPKHFKFKSIDLEIDGWYIKPELKEGEKAPVIVFVHGGPKGMYGY 404
Y + + +K + P+ S +E++GW I + AP I+F+HGGP YGY
Sbjct: 323 YRDIEYDPNPNIKGYTPERITVNSNGVEVEGWSIIKD----PNAPTILFIHGGPHMAYGY 378
Query: 405 YFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQ 464
+ E Q G+ ++Y NPRGS GY E+FA + G +DF+D++N + E
Sbjct: 379 GYFIEFQFFVDNGFNVIYANPRGSQGYGEEFAKACVGDWGGKDFEDLMNFVNTV--KERY 436
Query: 465 ADRERVGITGISYGGFMTNWALTQSDLFKAGISENGISYWLTSYAFSDIGLWFDKEVIG- 523
+ + + GITG SYGGFMTNW +T++ +F A ISE IS ++ SDIG WF+ G
Sbjct: 437 SLKGKFGITGGSYGGFMTNWIVTKTSMFSAAISERSISNLVSMCGTSDIGFWFNAIESGI 496
Query: 524 ENPLENENFRKL---SPLFYAKNVKAPLLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYI 580
+P E KL SP++Y KNVK P +LIH EDYRCP++Q+ FY LK G +
Sbjct: 497 ADPWSTEGIEKLMKMSPIYYVKNVKTPTMLIHGEEDYRCPIEQAEQFYVALKMQGVPTTL 556
Query: 581 AIFKRGAHGHSIRGSPRHRMKRYKLFMEFFERKL 614
++ +H H+ RG P++ + R K +E+F + L
Sbjct: 557 VRYQGDSHEHARRGKPKNMIDRLKTKLEWFSKYL 590
>pir||E75551 probable acyl-peptide hydrolase - Deinococcus radiodurans (strain
R1) >gi|6457834|gb|AAF09754.1|AE001879_2 (AE001879)
acyl-peptide hydrolase, putative [Deinococcus
radiodurans]
Length = 655
Score = 196 bits (494), Expect = 5e-49
Identities = 185/655 (28%), Positives = 298/655 (45%), Gaps = 82/655 (12%)
Query: 25 AYLSDPRIR--GSTIAYVLTKANLDNN----------KYESTIVLENLEDGSKRFIEDA- 71
A+ SDP++ G +A+VL + + ++ +Y S + L E G+ R + A
Sbjct: 18 AFPSDPQVSPDGKQVAFVLAQISEEDPAKPDKDFARPRYRSGLWLS--EGGAARPLTHAE 75
Query: 72 -----SMPRISPDGKKIAFMRFNEEKKVAQIWVADMKTLSAKKVLEAKN-IRSLEWNDDS 125
S PR SPDG+ +AF+R E K A + + +K A++V KN + +W+ D
Sbjct: 76 TGRGDSAPRWSPDGQNLAFVRSAGEVKAA-LMLLPLKGGEARRVTHFKNGVSGPQWSPDG 134
Query: 126 RRLLVIGFKRRDDE-DFIFEDDV---PAWFDNMGFFDGEK-TTFWIVDTEAEEVIEQFEK 180
R + +D+ D E V P + N + E+ W+ D EA+++ E +
Sbjct: 135 RFIAFTTTADTEDKRDERGEARVLTRPVYRANGADWLPERPAALWLYDVEADKLREWYA- 193
Query: 181 PRFSSGV--WHGDSIVVNVPYRDTIPRYFKYWNIYLWKD-------------GEEEKLFE 225
P G W DS V + + W W+ +KL +
Sbjct: 194 PEIGIGALSWWPDSRGVLIVQSED------EWQASQWRQDVYDLPLPTADAPAAPQKLLD 247
Query: 226 -KVSFHAI--DSDGKNILLYGKPEKKYMSEHDKLYIYD-GEVKGIMDSIDREAGQAKIKD 281
+ H + DG+ L G+P K +EH LY+ + G+ + + D G A D
Sbjct: 248 WNSAAHGLAPHPDGQRFALIGRPAGKGNTEHAHLYLIENGQHRRLDTGHDHPVGDAVGGD 307
Query: 282 GKV---------------YFTLYEEGSVNLYLWD--GDIKEIAKGKHWIMG-FDVDEK-V 322
V F+ GSV L+ G +K ++ F +E V
Sbjct: 308 CHVGAFPEGPRWLDGDTLLFSSTVRGSVGLFTAHIGGGVKAYDHDPQGVISAFTANEHGV 367
Query: 323 VYLKETATRLRELYIWDGEERQLTDYNGLIFSKLKTFEPKHFKFKSIDLEIDGWYIKPEL 382
++E+ATR E+ + +++TD + ++ EP+ F++ E +GW + PE
Sbjct: 368 ALIRESATRFPEVEL---NGQRVTDLHARFPFPVR--EPQRVTFETELGEGEGWVLLPEG 422
Query: 383 KEGEKAPVIVFVHGGPKGMYGYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLER 442
++ K P ++ +HGGP YG+ F +E QLMA++GY + Y NPRGS GY + + + R
Sbjct: 423 EQ--KVPALLNIHGGPHTDYGHGFTHEFQLMAARGYGVCYSNPRGSVGYGQAWVDAIYGR 480
Query: 443 TGLEDFQDILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQSDLFKAGISENGIS 502
G D D+LN + + P+ D + + G SYGGFMTNW + F+A I++ IS
Sbjct: 481 WGTVDADDLLNFFDRCLEAVPRLDAAKTAVMGGSYGGFMTNWITGHTTRFQAAITDRCIS 540
Query: 503 YWLTSYAFSDIGLWFDKEVIGENPLENENFRK---LSPLFYAKNVKAPLLLIHSLEDYRC 559
++ SDIGL F + +G + + K LSPL Y +NVK P L++HS+ D+RC
Sbjct: 541 NLISFGGTSDIGLRFWDDELGLDFSRRADALKLWDLSPLQYVENVKTPTLIVHSVLDHRC 600
Query: 560 PLDQSLMFYHVLKDLGKEVYIAIFKRGAHGHSIRGSPRHRMKRYKLFMEFFERKL 614
P++Q+ +Y L V F H S G P R+ R + + ER L
Sbjct: 601 PVEQAEQWYAALHKHQVPVRFVRFPEENHELSRSGRPDRRLTRLNEYFAWLERWL 655
>gb|AAG20414.1| (AE005114) acylaminoacyl-peptidase; YuxL [Halobacterium sp. NRC-1]
Length = 674
Score = 135 bits (337), Expect = 1e-30
Identities = 156/657 (23%), Positives = 258/657 (38%), Gaps = 80/657 (12%)
Query: 21 FTKFAYLSDPRIR--GSTIAYVLTKANLDNNKYESTIVLENLE---DGSKRFIE----DA 71
+ + A LS P + G +AYV T A D + + T + GS+RF DA
Sbjct: 9 YWELARLSQPAVSPTGDRVAYVRTTAERDGDTGQETASVHVAPVGGGGSRRFTAADGTDA 68
Query: 72 SMPRISPDGKKIAFM--RFNEEKKVAQIWVADMKTLSAKKVLEA-KNIRSLEWNDDSRRL 128
P SP G ++AF+ R + Q+WV + A ++ + + ++ W D R+
Sbjct: 69 E-PAWSPTGDRLAFVSTRGDAGGGRPQLWVVPVDGGEATRITDVIGGVSNIAWGPDGDRV 127
Query: 129 LVIGFKR---RDDE-----DFIFEDDVP--------AWFDNMGFFDGEKTTFWIVDTEAE 172
+ R R +E D +E D P + + + DG + ++ D A
Sbjct: 128 AFLQAVRPAERAEELDREHDGEYERDTPDPRVIDRQMYRGHTSYRDGARRHVYVADLAAG 187
Query: 173 EVIEQFEKPRFSSGVWHGDSIVVNVPYRDTIPRYFKY-WNIYLWKDGEEEKLFEKVSFHA 231
V G GD + P R + + W I + +
Sbjct: 188 RVDRVTAGVAECGGPAWGDDGTLYYPIRRGLDADDRLEWAIEAATPADSA---DSTVVTT 244
Query: 232 IDSDGKNILLYGK-------PEKKYMSEHDKLYIYD---GEVKGIMDSIDREAGQAKI-- 279
++ G + ++G P + ++D G + D +DR +
Sbjct: 245 VEGMGPTLAVHGSRVAYTTTPADDPTLTQTAVEVFDRDTGATDRLTDGVDRTVAERTAGH 304
Query: 280 -----KDGK-VYFTLYEEGSVNLYLW---DGDIKEIAKGKHWIMGFDVDEKVVYLKETAT 330
DG+ +Y +EG L GD + + G + F V V + ++
Sbjct: 305 APEWGPDGEHLYVCTPDEGGYVLRRVAADTGDDRVVLAGDRHVHAFSVSADAVAVVQSE- 363
Query: 331 RLRELYIWD------------GEERQLTDYNGLIFSKLKTFEPKHFKFKSIDLEIDGWYI 378
WD GEE LT N + +P+ +I GW +
Sbjct: 364 -------WDHPGEVVAATPMGGEEVTLTRANRDYLDERAVSKPESVWIDGPAGDIQGWVL 416
Query: 379 KP-ELKEGEKAPVIVFVHGGPKGMYGYY--FKYEMQLMASKGYYIVYVNPRGSNGYSEDF 435
P E E P++V VHGGP M+ +E Q +A++GY + + NPRGS GY +++
Sbjct: 417 TPPEFDPEETYPLVVNVHGGPHLMWSAAGTMWHEFQTLAARGYVVFWCNPRGSTGYGQEW 476
Query: 436 ALRVLERT-GLEDFQDILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQSDLFKA 494
LR +ER G D++ G+ + D + ITG S+GGFMT WA+ +D F
Sbjct: 477 -LRAVERDWGAVTLADVMAGVAAVTDRD-YVDADNAFITGGSFGGFMTGWAVGHTDAFAG 534
Query: 495 GISENGISYWLTSYAFSDIGLWFDKEVIGENPLENENFRKLSPLFYAKNVKAPLLLIHSL 554
+++ G+ Y +D + E + +N SP + V P LL+HS
Sbjct: 535 AVAQRGVYDLTGFYGTTDAYALVEGEFDTDPVRDNAFLWAQSPAAHTDAVDTPTLLVHSE 594
Query: 555 EDYRCPLDQSLMFYHVLKDLGKEVYIAIFKRGAHGHSIRGSPRHRMKRYKLFMEFFE 611
DYR P + + +FY +LK G + + + H S G P H + R + +F+
Sbjct: 595 ADYRTPANTAELFYRLLKKHGVDTRLVRYPGEGHDLSRSGDPGHVVDRIERIAAWFD 651
>emb|CAC11802.1| (AL445065) hypothetical protein [Thermoplasma acidophilum]
Length = 583
Score = 118 bits (294), Expect = 1e-25
Identities = 71/222 (31%), Positives = 117/222 (51%), Gaps = 2/222 (0%)
Query: 387 KAPVIVFVHGGPKGMYGYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLE 446
K P+IV++HGGP F + G+ + N RGS G +A + G +
Sbjct: 362 KNPLIVYIHGGPTSFSYASFLDRTSIYLGYGFNVFAPNYRGSVGKGRRYAELNVGDLGGK 421
Query: 447 DFQDILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQSDLFKAGISENGISYWLT 506
DF D+++GIE F K + +R+ ITG SYGG+M+ A+ ++D+F+A +S GIS W++
Sbjct: 422 DFDDVISGIE-FLKNTGKIATDRIYITGGSYGGYMSALAVMKTDIFRASVSLFGISDWVS 480
Query: 507 SYAFSDIGLWFDKEVIGENPLENENFRKLSPLFYAKNVKAPLLLIHSLEDYRCPLDQSLM 566
+ S++ LW D+ + +P + + + SP+ K P LL+H ++D P+ Q
Sbjct: 481 FHGVSNLHLW-DRLHMDADPWAFKKYDEYSPIRIMHEPKTPTLLMHGIKDPYVPIGQYYE 539
Query: 567 FYHVLKDLGKEVYIAIFKRGAHGHSIRGSPRHRMKRYKLFME 608
FY LK+ EV + +F R HG + + R + FM+
Sbjct: 540 FYRFLKEKNCEVRMIVFPREGHGFTEKEHIRRQYMETIRFMK 581
>pir||B82580 alanyl dipeptidyl peptidase XF2260 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9107416|gb|AAF85059.1|AE004038_8
(AE004038) alanyl dipeptidyl peptidase [Xylella
fastidiosa]
Length = 709
Score = 114 bits (283), Expect = 3e-24
Identities = 96/381 (25%), Positives = 179/381 (46%), Gaps = 35/381 (9%)
Query: 234 SDGKNILLYGKPEKKYMSEHDK-----LYIYDGEVKGIMDSIDREAGQAKIK-DGK-VYF 286
+DGK +LY + ++ E D+ + + G+V+ I DR A + + DGK +Y
Sbjct: 313 ADGK--MLYYRAMRRPGFEADRFGLMEMEVQSGKVREIAPHWDRSADEIALSADGKALYV 370
Query: 287 TLYEEGSVNLYLWDGDIKEIAKGK--HWIMGFDVDE------KVVYLKETATRLRELYIW 338
+ G L+ D IA GK W+ V K+ + + + ++++
Sbjct: 371 NADDHGEHPLFKVD-----IASGKVEKWVGEGSVHAPVLAGGKLAFARNSLKSADQIFVT 425
Query: 339 D----GEERQLTDYNGLIFSKLKTFEPKHFKFKSIDLE-IDGWYIKP-ELKEGEKAPVIV 392
D G + +T G + +++ + + F FK + E + G+ +KP + + G+K PV
Sbjct: 426 DAVARGPLQAITSATGEVLQQVRLGDFEQFSFKGWNDETVYGYVVKPYDYQPGKKYPVAF 485
Query: 393 FVHGGPKGMYG--YYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQD 450
+HGGP+G +G + +++ Q A +GY +V ++ GS GY + F + + G +D
Sbjct: 486 LIHGGPQGSFGNSWGYRWNPQTYAGQGYAVVMIDFHGSTGYGQAFTDAISQHWGDRPLED 545
Query: 451 ILNGIEEFFKLEPQADRERVGITGISYGGFMTNW-ALTQSDLFKAGISENGI-SYWLTSY 508
+ G + P + ++ G SYGG+M W A + +K + +G+ + Y
Sbjct: 546 LQKGWAAAQQQYPFLNGDKACALGASYGGYMVYWIAGHWNQPWKCLVDHDGVFDNRMMGY 605
Query: 509 AFSDIGLWFDKEVIGENPLEN-ENFRKLSPLFYAKNVKAPLLLIHSLEDYRCPLDQSLMF 567
A + LWF + G P EN + + +P+ + + P+L+IH +D+R P++Q L
Sbjct: 606 ATEE--LWFSEWENGGTPWENPAGYEQFNPVLHVDKWRVPMLVIHGQKDFRIPVEQGLAA 663
Query: 568 YHVLKDLGKEVYIAIFKRGAH 588
+ L+ G E + F H
Sbjct: 664 FGALQRKGIESKLLYFHDENH 684
>gb|AAF20265.1| (AF059279) dipeptidyl-peptidase [Entamoeba dispar]
Length = 663
Score = 110 bits (272), Expect = 5e-23
Identities = 74/273 (27%), Positives = 130/273 (47%), Gaps = 6/273 (2%)
Query: 322 VVYLKETATRLRELYIWDGEE-RQLTDYNGLIFSKLKTFEPKHFKFKSIDLEIDGWYIK- 379
++Y + T +EL+I++ + +Q+T N + S +K E K + + + +I
Sbjct: 365 IIYEYNSFTLPQELFIFENKVIKQITHINQEVLSTIKFGEYKEVHYTGANNDQIHAFITY 424
Query: 380 -PELKEGEKAPVIVFVHGGPKGMY--GYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFA 436
P +K K PVI++ HGGP+ + +++++ Q++A++GY + N GS Y ++F
Sbjct: 425 PPNMKTNTKYPVILYTHGGPESPWTNNFHYRWNPQVIAAQGYIVFAPNFHGSGSYGDEFL 484
Query: 437 LRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQ-SDLFKAG 495
+ + G F+D++ G++ EP D + G SYGG+M NW +Q + FK
Sbjct: 485 KAIRKNWGGWPFEDLMKGMDYLKTNEPIVDIDNACAMGASYGGYMMNWINSQNTGRFKCI 544
Query: 496 ISENGISYWLTSYAFSDIGLWFDKEVIGENPLENENFRKLSPLFYAKNVKAPLLLIHSLE 555
I +GI SY + D + + E +N ++K SPL Y P L IH
Sbjct: 545 ICHDGIMDSEGSYYYMDEMYFLETEFGYPMYEDNTYYKKYSPLNYVNGYNTPQLTIHGGS 604
Query: 556 DYRCPLDQSLMFYHVLKDLGKEVYIAIFKRGAH 588
DYR + + L+ E + I+ H
Sbjct: 605 DYRIDVVAGYQQFVTLQRKNIESKLVIYPEENH 637
>gb|AAF20264.1|AF059278_1 (AF059278) dipeptidyl-peptidase [Entamoeba histolytica]
Length = 665
Score = 108 bits (267), Expect = 2e-22
Identities = 74/274 (27%), Positives = 132/274 (48%), Gaps = 8/274 (2%)
Query: 322 VVYLKETATRLRELYIWDGEE-RQLTDYNGLIFSKLKTFEPKHFKFKSIDLEIDGWYIK- 379
++Y + T +EL++++ + +Q+T N + S +K E K + + + +I
Sbjct: 367 IIYEYNSFTLPQELFLYENKVIKQITHINQEVLSTIKFGEYKEIHYTGANNDQIHAFITY 426
Query: 380 -PELKEGEKAPVIVFVHGGPKGMY--GYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFA 436
P +K K PVI++ HGGP+ + +++++ Q++A++GY + N GS Y + F
Sbjct: 427 PPNMKTNTKYPVILYTHGGPESPWTNNFHYRWNPQVIAAQGYIVFAPNFHGSGSYGDAFL 486
Query: 437 LRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQ-SDLFKAG 495
+ + G F+D++ G++ EP D + G SYGG+M NW +Q + FK
Sbjct: 487 KAIRKNWGGWPFEDLMKGMDYLKTSEPLVDIDNACAMGASYGGYMMNWINSQNTGRFKCI 546
Query: 496 ISENGISYWLTSYAFSDIGLWFDKEVIGENPLENEN-FRKLSPLFYAKNVKAPLLLIHSL 554
I +GI SY + D ++F + G E++ ++K SPL Y P L IH
Sbjct: 547 ICHDGIMDSEGSYYYMD-EMYFLETEFGYPMYEDDTYYKKYSPLNYVNGYNTPQLTIHGG 605
Query: 555 EDYRCPLDQSLMFYHVLKDLGKEVYIAIFKRGAH 588
DYR + + L+ E + I+ H
Sbjct: 606 SDYRIDVVAGYQQFVTLQRKNIESKLVIYPEENH 639
>pir||T09631 probable acylaminoacyl-peptidase (EC 3.4.19.1) - Aspergillus
fumigatus >gi|2340046|gb|AAB67282.1| (L48074) secreted
dipeptidyl peptidase [Aspergillus fumigatus]
Length = 721
Score = 106 bits (261), Expect = 1e-21
Identities = 98/370 (26%), Positives = 166/370 (44%), Gaps = 34/370 (9%)
Query: 235 DGKNILLYGKPEKKYMSEHDKLYIYDGEVKGIMDSI----DREAGQAK-IKDGKVYFTLY 289
+G + + ++ Y S+ LY+Y K + S+ DR K DGK
Sbjct: 298 NGDKLAYFQMRDETYESDRALLYVYSLGSKKTIPSVAGDWDRSPDSVKWTPDGKTLIVGS 357
Query: 290 EE-GSVNLYLWDGDIKEIAKGKHWIMGFDVDEKVVYLKETATRLRELYIWD--------- 339
E+ G L+ + K+ K K++ G V +L +++ + +W
Sbjct: 358 EDLGRTRLFSLPANAKDDYKPKNFTDGGSVSA-YYFLPDSSLLVTGSALWTNWNVYTAKP 416
Query: 340 --GEERQLTDYNGLIFSKLKTFEPK---HFKFKSIDLEIDGWYIKPE-LKEGEKAPVIVF 393
G +++ N I +LK P F F+ +I W I PE + +K P+I F
Sbjct: 417 EKGVIKKIASANE-IDPELKGLGPSDISEFYFQGNFTDIHAWVIYPENFDKSKKYPLIFF 475
Query: 394 VHGGPKGMY--GYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQDI 451
+HGGP+G + G+ ++ + A +GY +V NP GS G+ + + G + D+
Sbjct: 476 IHGGPQGNWADGWSTRWNPKAWADQGYVVVAPNPTGSTGFGQALTTAIQNNWGGAPYDDL 535
Query: 452 LNGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQSDL---FKAGISENGISYWLTSY 508
+ E + D + G SYGGFM NW + S L FKA +S +G ++
Sbjct: 536 VKCWEYVHENLDYVDTDHGVAAGASYGGFMINW-IQGSPLGRKFKALVSHDGT--FVADA 592
Query: 509 AFSDIGLWF-DKEVIGENPLENENFRKLSPLFYAKNVK--APLLLIHSLEDYRCPLDQSL 565
S LWF +E G +N+R+ P + ++ P+L+IHS +DYR P+ + L
Sbjct: 593 KVSTEELWFMQREFNGTFWDARDNYRRWDPSAPERILQFATPMLVIHSDKDYRLPVAEGL 652
Query: 566 MFYHVLKDLG 575
++VL++ G
Sbjct: 653 SLFNVLQERG 662
>gb|AAD41777.1|AF125190_1 (AF125190) alanyl dipeptidyl peptidase [Aspergillus oryzae]
Length = 725
Score = 100 bits (246), Expect = 6e-20
Identities = 93/369 (25%), Positives = 165/369 (44%), Gaps = 33/369 (8%)
Query: 235 DGKNILLYGKPEKKYMSEHDKLYIY----DGEVKGIMDSIDREAGQAK-IKDGKVYFTLY 289
D K I + ++ Y ++H LY+Y + + + DR K D + +
Sbjct: 302 DSKKIAYWQMADESYEADHRTLYVYTVGSEETIPSLAADWDRSLDSVKWADDDNLIIGVE 361
Query: 290 EEGSVNLYLWDGDIKEIAKGKHWIMGFDVDEKVVYLKETATRLRELYIWD---------- 339
+ G L+ D + K K++ G V L ++ + IW
Sbjct: 362 DAGRSRLFSIPADAGDDYKPKNFTDG-GVVSAYYQLPDSTYLVTSTAIWTSWNVYIASPE 420
Query: 340 -GEERQLTDYNGLIFSKLKTFEPK---HFKFKSIDLEIDGWYIKPELKEGEKA-PVIVFV 394
G + L N I +LK P+ F ++ +I + I PE + K+ P++ ++
Sbjct: 421 KGVIKTLATANK-IDPELKGLGPEIVDEFYYEGNWTKIQAFVIYPENFDKSKSYPLLYYI 479
Query: 395 HGGPKGMY--GYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQDIL 452
HGGP+ + + ++ ++ A +GY +V NP GS+G+ + + + G ++D++
Sbjct: 480 HGGPQSSWLDSWSTRWNPKVFADQGYVVVAPNPTGSSGFGDALQDAIQNQWGGYPYEDLV 539
Query: 453 NGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQSDL---FKAGISENGISYWLTSYA 509
G E + D + G SYGGFM NW + SDL FKA +S +G ++
Sbjct: 540 KGWEYVNENFDFIDTDNGVAAGASYGGFMINW-IQGSDLGRKFKALVSHDGT--FVADAK 596
Query: 510 FSDIGLWFDKEVIGENPLEN-ENFRKLSPLFYAKNVK--APLLLIHSLEDYRCPLDQSLM 566
S LWF + +N EN+R+ P + +K P+L+IHS DYR P+ + L
Sbjct: 597 VSTEELWFMQHEFNGTFWDNRENYRRWDPSAPERILKFSTPMLIIHSDLDYRLPVSEGLS 656
Query: 567 FYHVLKDLG 575
+++L++ G
Sbjct: 657 LFNILQERG 665
>gb|AAK41653.1| Acylaminoacyl-peptidase, putative (apeH-1) [Sulfolobus
solfataricus]
Length = 536
Score = 99.1 bits (243), Expect = 1e-19
Identities = 99/351 (28%), Positives = 160/351 (45%), Gaps = 33/351 (9%)
Query: 249 YMSEHD---KLY---IYDGEVKGIMDSIDREAGQAKIKDGKVYFTLYEEGSVNLYLWDGD 302
++S H+ K+Y I GE++ I +S D E +A G + + G+ L
Sbjct: 187 FLSNHEDLSKVYEFNILKGEIRKIRES-DYEIFEAIPYKGSIAYVEDRHGNFVLI----H 241
Query: 303 IKEIAKGKHWIMGFDVDEKVVYLKETA-TRLRELYIWDGEERQLTDYNGLIFSKLKTFEP 361
KEI + + VD +Y + R +LY + + +LTD + +K +P
Sbjct: 242 EKEIVN-EGFTYSLKVDGDYIYFVNSKHDRSADLYRYGKKVERLTD--SMNDAKGNFIKP 298
Query: 362 KHFKFKSIDLEIDGWYIKPELKEGEKAPVIVFVHGGPKGMYGYYFKYEMQLMASKGYYIV 421
K + S L I Y K GE IV++HGGP F E+Q +G+ ++
Sbjct: 299 KVVSYDSNGLRI---YALLYEKGGEDKG-IVYIHGGPDWECVNSFNPEIQFFMERGFKVI 354
Query: 422 YVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGITGISYGGFM 481
N RGS GY F + G + D++N ++ +++ ITG SYGG++
Sbjct: 355 CPNYRGSIGYGRRFNHLNDKDPGGGELLDVINSVKVL-------GVKKIAITGASYGGYL 407
Query: 482 TNWALTQ-SDLFKAGISENGISYWLTSYAFS-DIGLWFDKEVIGENPLENENF-RKLSPL 538
T A T+ SDL+ + ++ W T +I +D+ +G + EN R SP+
Sbjct: 408 TMMATTKFSDLWCSAVAVVPFVNWFTEKKLEREILQLYDEIKVGND----ENLLRDRSPI 463
Query: 539 FYAKNVKAPLLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFKRGAHG 589
F+ +K LLL+ D RCP +++L L+ LG+EV I+K HG
Sbjct: 464 FFIDRIKTSLLLLAGENDPRCPAEETLQVVEELRKLGREVKYKIYKDEGHG 514
>pir||T15945 hypothetical protein F01F1.5 - Caenorhabditis elegans
>gi|529702|gb|AAC46639.1| (U13070) similar to
acylaminoacyl-peptidase [Caenorhabditis elegans]
Length = 629
Score = 98.7 bits (242), Expect = 2e-19
Identities = 61/236 (25%), Positives = 114/236 (47%), Gaps = 12/236 (5%)
Query: 356 LKTFEPKHFKFKSIDLEIDGWYIKPELKEGEKAPVIVFVHGGPKGMYGYYFKYEMQLMAS 415
L+ EP+ F FKS +++ G PV++ HGGP + Q S
Sbjct: 365 LEISEPEEFVFKSDGVDVSA---------GTLPPVLLLGHGGPTAPAQNNLDLKKQFFTS 415
Query: 416 KGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGITGI 475
+G + VN RGS G+ +F + + G+ D D+LNG + + + + D E+V ITG
Sbjct: 416 RGIAVFDVNYRGSTGFGTEFRRMLYKNCGVADRDDMLNGAKALVE-QGKVDAEKVLITGS 474
Query: 476 SYGGFM-TNWALTQSDLFKAGISENGISYWLT-SYAFSDIGLWFDKEVIGENPLENENFR 533
S GG++ + ++ ++ KA +S G++ L + +++ +IG+ P + +
Sbjct: 475 SSGGYLILSCLISPKNIIKAAVSVYGVADLLALDEDTHKLERCYNEMLIGKYPEQASIYE 534
Query: 534 KLSPLFYAKNVKAPLLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFKRGAHG 589
+ SP+++ ++ P+ +H ED P+ QS+ Y ++ G + +F HG
Sbjct: 535 ERSPIYHIDKIRTPIAFLHGREDTVVPMSQSITMYEKIRASGVTTALMLFDGEGHG 590
>emb|CAB88242.1| (AL353012) putative dipeptidyl peptidase; possibly secreted
[Schizosaccharomyces pombe]
Length = 683
Score = 96.0 bits (235), Expect = 1e-18
Identities = 62/222 (27%), Positives = 109/222 (48%), Gaps = 7/222 (3%)
Query: 373 IDGWYIKPE-LKEGEKAPVIVFVHGGPKGMY--GYYFKYEMQLMASKGYYIVYVNPRGSN 429
I W +KPE + +K PV V +HGGP+G + + ++ + A+ G+ + ++P GS
Sbjct: 429 IHAWIVKPESFDKSKKYPVAVLIHGGPQGSWTDSWSTRWNPAVFANAGFIVFALDPTGST 488
Query: 430 GYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQ- 488
GY + F + G + ++DI G+E AD E++ G SYGG+M NW
Sbjct: 489 GYGQRFTDSIALDWGGKPYKDIELGVEYIKNHLSYADSEKMVALGASYGGYMINWIQGHP 548
Query: 489 -SDLFKAGISENGISYWLTSYAFSDIGLWFDKEVIGENPLENE-NFRKLSPLFYAKNVKA 546
F+A + +G+ L ++ ++ L+F G P EN + + +P +
Sbjct: 549 LGRQFRALVCHDGVFNTLNTF-YNTEELYFSIHDFGGTPWENRVIYERWNPSNFVNYWAT 607
Query: 547 PLLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFKRGAH 588
P L+IHS +DYR + + ++VL+ G + +F+ H
Sbjct: 608 PELVIHSSKDYRLTESEGIAAFNVLQYKGIPSRLLVFEDENH 649
>pir||H72474 probable acylamino-acid-releasing enzyme APE2441 - Aeropyrum pernix
(strain K1) >gi|5106145|dbj|BAA81456.1| (AP000064) 591aa
long hypothetical acylamino-acid-releasing enzyme
[Aeropyrum pernix]
Length = 591
Score = 95.2 bits (233), Expect = 2e-18
Identities = 95/358 (26%), Positives = 161/358 (44%), Gaps = 48/358 (13%)
Query: 281 DGKVYFTLYEE-GSVNLYLWDGDIKEIAKGKHWIMGFDVDEKV---VYLKETATRLRELY 336
+ +VY T +E GS+ L I+ + +G ++ D++EK+ V+ T E+Y
Sbjct: 255 ESRVYTTKIDERGSL---LQPRPIEGLPRGS--LLSLDLNEKLGLAVFSLSTPKHGIEIY 309
Query: 337 I--WDGEERQLTDYNGLIFSKLKTFEPKHFKFKSID-LEIDGWYIKPELKEGEKAPVIVF 393
I +LT + + EP+HF ++S D +++ KP+ P +V+
Sbjct: 310 IAGLGRSASRLTVSPKAWLREDEFVEPEHFSYESFDGIKVRALLYKPDKPLYTPPPAVVY 369
Query: 394 VHGGPKGMYGYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQDILN 453
+HGGP+ F Q +A+ G + N RGS GY F L+D + ++
Sbjct: 370 LHGGPESQERVRFNVFPQALAAIGIATIAPNYRGSTGYGRRFV-------HLDDVEKRMD 422
Query: 454 GIEEFFKLEPQA------DRERVGITGISYGGFMTNWALT-QSDLFKAGISENGISYWLT 506
+ + + A D R+ + G SYGG++T +L DL+K G+ GI +T
Sbjct: 423 AVRDVYYAVKAAVEAGLVDGSRLCVMGGSYGGYLTLMSLAIYPDLWKCGVEIVGIVNLVT 482
Query: 507 ----------SYAFSDIGLWFDKEVIGENPLENENFRKLSPLFYAKNVKAPLLLIHSLED 556
Y ++ G D +V GE L KLSP+ Y +N+KAPL++IH +D
Sbjct: 483 FIRNTSPYRRRYRIAEYG---DPDVHGEIML------KLSPITYVENMKAPLMVIHGAKD 533
Query: 557 YRCPLDQSLMFYHVLKDLGKEVYIAIFKRGAHGHSIRGSPRHRMKRYKLFMEFFERKL 614
R P+ ++ L G V + + GH I ++++ Y+ +EF L
Sbjct: 534 PRVPVSEAEQLVEALSSRG--VRVRYVRLEDEGHGI-VKLENKLRVYREALEFIYENL 588
>dbj|BAB09360.1| (AB026661) acyl-peptide hydrolase-like [Arabidopsis thaliana]
Length = 678
Score = 92.8 bits (227), Expect = 1e-17
Identities = 67/238 (28%), Positives = 111/238 (46%), Gaps = 7/238 (2%)
Query: 386 EKAPVIVFVHGGPKGMYGYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGL 445
EK P++V HGGP +Q S+G+ V VN GS GY ++ R+L + G+
Sbjct: 438 EKPPLLVKSHGGPTAESRGSLNLNIQYWTSRGWAFVDVNYGGSTGYGREYRERLLRQWGI 497
Query: 446 EDFQDILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQSDLFKAGISENGISYWL 505
D D G ++ +AD +R+ I+G S GG+ T +L D+FKAG S G++
Sbjct: 498 VDVDDCC-GCAKYLVSSGKADVKRLCISGGSAGGYTTLASLAFRDVFKAGASLYGVA--- 553
Query: 506 TSYAFSDIGLWFDKEVIGENPLENENFRKLSPLFYAKNVKAPLLLIHSLEDYRCPLDQSL 565
+ G F+ I + ++F + SP+ + P++L LED DQS
Sbjct: 554 DLKMLKEEGHKFESRYIDNLVGDEKDFYERSPINFVDKFSCPIILFQGLEDKVVTPDQSR 613
Query: 566 MFYHVLKDLGKEVYIAIFKRGAHGHSIRGSPRHRMKRYKLFMEFFERKLKKYEEGFDV 623
Y LK G V + ++ HG + ++ +++ M FF R + ++ D+
Sbjct: 614 KIYEALKKKGLPVALVEYEGEQHGFRKAENIKYTLEQQ---MVFFARVVGGFKVADDI 668
>gb|AAK42319.1| Acylaminoacyl-peptidase, putative (apeH-2) [Sulfolobus
solfataricus]
Length = 569
Score = 92.4 bits (226), Expect = 1e-17
Identities = 67/238 (28%), Positives = 114/238 (47%), Gaps = 22/238 (9%)
Query: 355 KLKTFEPKHFKFKSIDLEIDGWYIKPELKEGEKAPVIVFVHGGPKGMYGYYFKYEMQLMA 414
K+ E ++ K K+ D+E+ W IK ++ I+++HGGP + + +
Sbjct: 319 KVDVGEVEYVKVKT-DVEVPTWVIKRKIPGN----TIIYIHGGPWSEVDNSWNLLIAPLV 373
Query: 415 SKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGITG 474
GY ++ N RGS GY F + G D +D++ + + +E +VGI G
Sbjct: 374 LAGYNVIAPNYRGSTGYGSKFMFMNIGDAGGGDLRDVVKVRD--YAIETGITN-KVGIMG 430
Query: 475 ISYGGFMTNWAL-TQSDLFKAGISENGISYWLTSYAFSDIGLWFDKEVIGENPLENENFR 533
SYGG+MT A+ + D + GI+ ++ W+ Y SD E++ N + +
Sbjct: 431 YSYGGYMTLLAVGKEPDKWDFGIAGAAVADWVEMYDLSDSLFRGFMEILF-NGKNIDLMK 489
Query: 534 KLSPLFYAKNVKAPLLLIHSLEDYRCPLDQSLMF------------YHVLKDLGKEVY 579
+ SP+ Y +NVK PL +IHS D R PL+ + + +HV+ +LG +Y
Sbjct: 490 ERSPITYVRNVKVPLCIIHSQNDTRTPLNPVMRYIQELQRTGKTYEFHVIPNLGHAIY 547
>pir||S74053 probable acylaminoacyl-peptidase (EC 3.4.19.1) - Sulfolobus
solfataricus >gi|1707747|emb|CAA69467.1| (Y08256)
acylamino-acid-releasing enzyme [Sulfolobus
solfataricus]
Length = 569
Score = 92.4 bits (226), Expect = 1e-17
Identities = 67/238 (28%), Positives = 114/238 (47%), Gaps = 22/238 (9%)
Query: 355 KLKTFEPKHFKFKSIDLEIDGWYIKPELKEGEKAPVIVFVHGGPKGMYGYYFKYEMQLMA 414
K+ E ++ K K+ D+E+ W IK ++ I+++HGGP + + +
Sbjct: 319 KVDVGEVEYVKVKT-DVEVPTWVIKRKIPGN----TIIYIHGGPWSEVDNSWNLLIAPLV 373
Query: 415 SKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGITG 474
GY ++ N RGS GY F + G D +D++ + + +E +VGI G
Sbjct: 374 LAGYNVIAPNYRGSTGYGSKFMFMNIGDAGGGDLRDVVKVRD--YAIETGITN-KVGIMG 430
Query: 475 ISYGGFMTNWAL-TQSDLFKAGISENGISYWLTSYAFSDIGLWFDKEVIGENPLENENFR 533
SYGG+MT A+ + D + GI+ ++ W+ Y SD E++ N + +
Sbjct: 431 YSYGGYMTLLAVGKEPDKWDFGIAGAAVADWVEMYDLSDSLFRGFMEILF-NGKNIDLMK 489
Query: 534 KLSPLFYAKNVKAPLLLIHSLEDYRCPLDQSLMF------------YHVLKDLGKEVY 579
+ SP+ Y +NVK PL +IHS D R PL+ + + +HV+ +LG +Y
Sbjct: 490 ERSPITYVRNVKVPLCIIHSQNDTRTPLNPVMRYIQELQRTGKTYEFHVIPNLGHAIY 547
>pir||T35378 probable peptide hydrolase - Streptomyces coelicolor
>gi|5123885|emb|CAB45477.1| (AL079348) putative peptide
hydrolase [Streptomyces coelicolor A3(2)]
Length = 606
Score = 92.4 bits (226), Expect = 1e-17
Identities = 71/231 (30%), Positives = 111/231 (47%), Gaps = 8/231 (3%)
Query: 389 PVIVFVHGGPKGMYGYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDF 448
P + +HGGP F GY +V VN RGS GY + + R GL +
Sbjct: 380 PTVFDIHGGPTWHDSDSFAAGPAAWVDHGYAVVRVNYRGSTGYGRAWTDALKHRVGLIEL 439
Query: 449 QDILNGIEEFFKLEPQADRERVGITGISYGGFMTNWAL-TQSDLFKAGISENGISYWLTS 507
+DI + E+ AD ER+ +TG S+GG++T + TQ + + GI+ ++ ++T+
Sbjct: 440 EDIA-AVREWAVASGLADPERLILTGGSWGGYLTLLGIGTQPEAWTLGIAAVPVADYVTA 498
Query: 508 YAFSDIGLW-FDKEVIGENPLE-NENFRKLSPLFYAKNVKAPLLLIHSLEDYRCPLDQSL 565
Y GL D+ ++G P E E F SPL Y VKAP+ + + D RCP+ Q
Sbjct: 499 YHDEMEGLKALDRTLLGGTPEEVPERFEASSPLTYVDEVKAPVYISAGVNDPRCPIRQVE 558
Query: 566 MFYHVLKDLGKEVYIAIFKRGAHGHSIRGSPRHRMKRYKLFMEFFERKLKK 616
+ L+ G + + G HG + R+K+ +L ++F R L K
Sbjct: 559 NYVERLEARGAVHEVYRYDAG-HGSLV---VDERIKQVRLELDFASRNLPK 605
>pir||F82858 dipeptidyl-peptidase XF0015 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9104777|gb|AAF82828.1|AE003856_7
(AE003856) dipeptidyl-peptidase [Xylella fastidiosa]
Length = 795
Score = 92.1 bits (225), Expect = 2e-17
Identities = 76/288 (26%), Positives = 133/288 (45%), Gaps = 20/288 (6%)
Query: 340 GEERQLTDYNGLIFSKLKTFEPKHFKFKSIDLE--IDGWYIKPELKEGEKA-PVIVFVHG 396
G+ R LTD F + +P++ + S I G Y P + EK P+++FVHG
Sbjct: 517 GQARVLTDTRTSTFKAKQWIQPEYVQIPSKHGAGVIWGKYYGPASLQPEKRYPIVMFVHG 576
Query: 397 GP-----KGMYGYYFKYEM--QLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQ 449
Y YF+ +M L+ KGY ++ ++ R S G+ D+ + G + +
Sbjct: 577 AGYLQNVSARYPSYFREQMFHTLLVQKGYIVLDLDYRASAGHGRDWRTAIYRNMGHPELE 636
Query: 450 DILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQS-DLFKAGISENGISYWLTSY 508
D L+G++ + Q DR R G+ G SYGGFMT A+ ++ FKAG + + W+
Sbjct: 637 DYLDGLD-WLVAHKQGDRRRAGMYGGSYGGFMTYMAMFRAPGTFKAGAALRPVGDWM--- 692
Query: 509 AFSDIGLWFDKEVIGENPLENENFRKLSPLFYAKNVKAPLLLIHSLEDYRCPLDQSLMFY 568
+ ++ L+ + +++ S + YA+ ++ LL++H + D S+
Sbjct: 693 ---QYNHEYTSNILNTPELDPDAYQRSSAINYAEALQGHLLILHGMIDDNVFFKDSVDMV 749
Query: 569 HVLKDLGKEVYIAIFKRGAHGHSIRGSPRHRMKRYKLFMEFFERKLKK 616
L +L K+ + I HS P + YK ++ FE +LK+
Sbjct: 750 QKLIELRKDNW-EIVPYPLERHSFT-HPDAWVDEYKRILKLFETQLKQ 795
>pir||S75772 hypothetical protein slr0825 - Synechocystis sp. (strain PCC 6803)
>gi|1001263|dbj|BAA10507.1| (D64003) hypothetical
protein [Synechocystis sp.]
Length = 637
Score = 91.3 bits (223), Expect = 3e-17
Identities = 64/203 (31%), Positives = 98/203 (47%), Gaps = 4/203 (1%)
Query: 389 PVIVFVHGGPKGMYGYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDF 448
P++V HGGP G ++Q S+G+ V VN GS GY D+ R+ + G+ D
Sbjct: 408 PLLVKSHGGPTAAAGNSLSLKIQYWTSRGFAYVDVNYGGSTGYGRDYRQRLNGQWGIVDV 467
Query: 449 QDILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQSDLFKAGISENGISYWLTSY 508
D +N + + D E++ I+G S GG+ T ALT ++FKAG S G+S LT+
Sbjct: 468 ADCVNA-ARYLADQGLVDGEQLAISGGSAGGYTTLAALTFHNVFKAGASYYGVSD-LTAL 525
Query: 509 AFS--DIGLWFDKEVIGENPLENENFRKLSPLFYAKNVKAPLLLIHSLEDYRCPLDQSLM 566
A + +IG P + + + SP+ +A + P++ LED P +Q+ M
Sbjct: 526 ATDTHKFEARYLDGLIGPYPERKDLYERRSPVNHADQLTCPVIFFQGLEDKVVPPNQTEM 585
Query: 567 FYHVLKDLGKEVYIAIFKRGAHG 589
LK G +V F HG
Sbjct: 586 MVQALKAKGIKVEYVAFPEEQHG 608
>pir||JU0132 acylaminoacyl-peptidase (EC 3.4.19.1) [validated] - pig
>gi|1332717|gb|AAB36056.1| acylamino acid-releasing
enzyme, AARE {EC 3.4.19.1} [swine, liver, Peptide, 732
aa] >gi|1583737|prf||2121361A acyl-AA releasing enzyme
[Sus scrofa domestica]
Length = 732
Score = 86.6 bits (211), Expect = 8e-16
Identities = 62/242 (25%), Positives = 112/242 (45%), Gaps = 14/242 (5%)
Query: 360 EPKHFKFKSIDLEIDGWYIKPELK-EGEKAPVIVFVHGGPKGMYGYYFKYEMQLMASKGY 418
+ +H ++ +D E ++P E + P++V HGGP + + ++ G+
Sbjct: 473 QQEHVQYAGLDFE--AILLQPSNSPEKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGF 530
Query: 419 YIVYVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGITGISYG 478
++ VN RGS G+ +D L + G +D +D+ +E+ + E D RV + G S+G
Sbjct: 531 AVLLVNYRGSTGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQ-EEHFDAGRVALMGGSHG 589
Query: 479 GFMTNWALTQ-SDLFKAGISENGISYWLTSYAFSDIGLW--------FDKEVIGENPLEN 529
GF++ + Q + + A + N + + +DI W + + + + +
Sbjct: 590 GFLSCHLIGQYPETYSACVVRNPVINIASMMGSTDIPDWCMVEAGFSYSSDCLPDLSVWA 649
Query: 530 ENFRKLSPLFYAKNVKAPLLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFKRGAHG 589
K SP+ YA VK PLLL+ ED R P Q + +Y VLK V + ++ + H
Sbjct: 650 AMLDK-SPIKYAPQVKTPLLLMLGQEDRRVPFKQGMEYYRVLKARNVPVRLLLYPKSTHA 708
Query: 590 HS 591
S
Sbjct: 709 LS 710
>sp|P19205|ACPH_PIG ACYLAMINO-ACID-RELEASING ENZYME (ACYL-PEPTIDE HYDROLASE) (APH)
(ACYLAMINOACYL-PEPTIDASE) >gi|217672|dbj|BAA00411.1|
(D00524) acylamino acid-releasing enzyme [Sus scrofa]
Length = 732
Score = 86.6 bits (211), Expect = 8e-16
Identities = 62/242 (25%), Positives = 112/242 (45%), Gaps = 14/242 (5%)
Query: 360 EPKHFKFKSIDLEIDGWYIKPELK-EGEKAPVIVFVHGGPKGMYGYYFKYEMQLMASKGY 418
+ +H ++ +D E ++P E + P++V HGGP + + ++ G+
Sbjct: 473 QQEHVQYAGLDFE--AILLQPSNSPEKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGF 530
Query: 419 YIVYVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGITGISYG 478
++ VN RGS G+ +D L + G +D +D+ +E+ + E D RV + G S+G
Sbjct: 531 AVLLVNYRGSTGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQ-EEHFDAGRVALMGGSHG 589
Query: 479 GFMTNWALTQ-SDLFKAGISENGISYWLTSYAFSDIGLW--------FDKEVIGENPLEN 529
GF++ + Q + + A + N + + +DI W + + + + +
Sbjct: 590 GFLSCHLIGQYPETYSACVVRNPVINIASMMGSTDIPDWCMVEAGFSYSSDCLPDLSVWA 649
Query: 530 ENFRKLSPLFYAKNVKAPLLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFKRGAHG 589
K SP+ YA VK PLLL+ ED R P Q + +Y VLK V + ++ + H
Sbjct: 650 AMLDK-SPIKYAPQVKTPLLLMLGQEDRRVPFKQGMEYYRVLKARNVPVRLLLYPKSTHA 708
Query: 590 HS 591
S
Sbjct: 709 LS 710
>gi|9951917 N-acylaminoacyl-peptide hydrolase; oxidized protein hydrolase;
acylaminoacyl-peptidase [Homo sapiens]
>gi|1703089|sp|P13798|ACPH_HUMAN
ACYLAMINO-ACID-RELEASING ENZYME (ACYL-PEPTIDE HYDROLASE)
(APH) (ACYLAMINOACYL-PEPTIDASE) (DNF15S2 PROTEIN)
>gi|2118063|pir||JC4655 acylaminoacyl-peptidase (EC
3.4.19.1) - human >gi|556514|dbj|BAA07476.1| (D38441)
acylamino acid-releasing enzyme [Homo sapiens]
Length = 732
Score = 85.4 bits (208), Expect = 2e-15
Identities = 56/214 (26%), Positives = 100/214 (46%), Gaps = 11/214 (5%)
Query: 387 KAPVIVFVHGGPKGMYGYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLE 446
+ P++V HGGP + + ++ G+ ++ VN RGS G+ +D L + G +
Sbjct: 499 QVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGSTGFGQDSILSLPGNVGHQ 558
Query: 447 DFQDILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQ-SDLFKAGISENGISYWL 505
D +D+ +E+ + E D V + G S+GGF++ + Q + ++A ++ N +
Sbjct: 559 DVKDVQFAVEQVLQ-EEHFDASHVALMGGSHGGFISCHLIGQYPETYRACVARNPVINIA 617
Query: 506 TSYAFSDIGLW--------FDKEVIGENPLENENFRKLSPLFYAKNVKAPLLLIHSLEDY 557
+ +DI W F + + + + E K SP+ Y VK PLLL+ ED
Sbjct: 618 SMLGSTDIPDWCVVEAGFPFSSDCLPDLSVWAEMLDK-SPIRYIPQVKTPLLLMLGQEDR 676
Query: 558 RCPLDQSLMFYHVLKDLGKEVYIAIFKRGAHGHS 591
R P Q + +Y LK V + ++ + H S
Sbjct: 677 RVPFKQGMEYYRALKTRNVPVRLLLYPKSTHALS 710
>gb|AAF37321.1|AF141383_1 (AF141383) oxidized protein hydrolase [Homo sapiens]
Length = 732
Score = 85.4 bits (208), Expect = 2e-15
Identities = 56/214 (26%), Positives = 100/214 (46%), Gaps = 11/214 (5%)
Query: 387 KAPVIVFVHGGPKGMYGYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLE 446
+ P++V HGGP + + ++ G+ ++ VN RGS G+ +D L + G +
Sbjct: 499 QVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGSTGFGQDSILSLPGNVGHQ 558
Query: 447 DFQDILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQ-SDLFKAGISENGISYWL 505
D +D+ +E+ + E D V + G S+GGF++ + Q + ++A ++ N +
Sbjct: 559 DVKDVQFAVEQVLQ-EEHFDASHVALMGGSHGGFISCHLIGQYPETYRACVARNPVINIA 617
Query: 506 TSYAFSDIGLW--------FDKEVIGENPLENENFRKLSPLFYAKNVKAPLLLIHSLEDY 557
+ +DI W F + + + + E K SP+ Y VK PLLL+ ED
Sbjct: 618 SMLGSTDIPDWCVVEAGFPFSSDCLPDLSVWAEMLDK-SPIRYIPQVKTPLLLMLGQEDR 676
Query: 558 RCPLDQSLMFYHVLKDLGKEVYIAIFKRGAHGHS 591
R P Q + +Y LK V + ++ + H S
Sbjct: 677 RVPFKQGMEYYRALKTRNVPVRLLLYPKSTHALS 710
>gi|11431488 N-acylaminoacyl-peptide hydrolase [Homo sapiens]
Length = 732
Score = 85.4 bits (208), Expect = 2e-15
Identities = 56/214 (26%), Positives = 100/214 (46%), Gaps = 11/214 (5%)
Query: 387 KAPVIVFVHGGPKGMYGYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLE 446
+ P++V HGGP + + ++ G+ ++ VN RGS G+ +D L + G +
Sbjct: 499 QVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGSTGFGQDSILSLPGNVGHQ 558
Query: 447 DFQDILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQ-SDLFKAGISENGISYWL 505
D +D+ +E+ + E D V + G S+GGF++ + Q + ++A ++ N +
Sbjct: 559 DVKDVQFAVEQVLQ-EEHFDASHVALMGGSHGGFISCHLIGQYPETYRACVARNPVINIA 617
Query: 506 TSYAFSDIGLW--------FDKEVIGENPLENENFRKLSPLFYAKNVKAPLLLIHSLEDY 557
+ +DI W F + + + + E K SP+ Y VK PLLL+ ED
Sbjct: 618 SMLGSTDIPDWCVVEAGFPFSSDCLPDLSVWAEMLDK-SPIRYIPQVKTPLLLMLGQEDR 676
Query: 558 RCPLDQSLMFYHVLKDLGKEVYIAIFKRGAHGHS 591
R P Q + +Y LK V + ++ + H S
Sbjct: 677 RVPFKQGMEYYRALKTRNVPVRLLLYPKSTHALS 710
>gi|6978513 n-acylaminoacyl-peptide hydrolase [Rattus norvegicus]
>gi|113178|sp|P13676|ACPH_RAT ACYLAMINO-ACID-RELEASING
ENZYME (ACYL-PEPTIDE HYDROLASE) (APH)
(ACYLAMINOACYL-PEPTIDASE) >gi|91923|pir||S07624
acylaminoacyl-peptidase (EC 3.4.19.1) - rat
>gi|202932|gb|AAA88506.1| (J04733) acyl-peptide
hydrolase [Rattus norvegicus]
Length = 732
Score = 84.7 bits (206), Expect = 3e-15
Identities = 61/233 (26%), Positives = 105/233 (44%), Gaps = 14/233 (6%)
Query: 370 DLEIDGWYIKPELKEGE-KAPVIVFVHGGPKGMYGYYFKYEMQLMASKGYYIVYVNPRGS 428
DL+ + ++P + + P++V HGGP + + ++ G+ ++ VN RGS
Sbjct: 481 DLDFEAILLQPSNPPDKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGS 540
Query: 429 NGYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQ 488
G+ +D L + G +D +D+ +E+ + E D RV + G S+GGF++ + Q
Sbjct: 541 TGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQ-EEHFDARRVALMGGSHGGFLSCHLIGQ 599
Query: 489 -SDLFKAGISENGISYWLTSYAFSDIGLWFDKEVIGENPLEN---------ENFRKLSPL 538
+ + A I+ N + + +DI W E P N E SP+
Sbjct: 600 YPETYSACIARNPVINIASMMGSTDIPDWCMVET--GFPYSNSCLPDLNVWEEMLDKSPI 657
Query: 539 FYAKNVKAPLLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFKRGAHGHS 591
Y VK P+LL+ ED R P Q + +Y LK V + ++ + H S
Sbjct: 658 KYIPQVKTPVLLMLGQEDRRVPFKQGMEYYRALKARNVPVRLLLYPKSNHALS 710
>emb|CAA33040.1| (X14915) acyl-peptide hydrolase [Rattus norvegicus]
Length = 729
Score = 83.5 bits (203), Expect = 7e-15
Identities = 58/229 (25%), Positives = 105/229 (45%), Gaps = 9/229 (3%)
Query: 370 DLEIDGWYIKPELKEGE-KAPVIVFVHGGPKGMYGYYFKYEMQLMASKGYYIVYVNPRGS 428
DL+ + ++P + + P++V HGGP + + ++ G+ ++ VN RGS
Sbjct: 481 DLDFEAILLQPSNPPDKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGS 540
Query: 429 NGYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQ 488
G+ +D L + G +D +D+ +E+ + E D RV + G S+GGF++ + Q
Sbjct: 541 TGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQ-EEHFDARRVALMGGSHGGFLSCHLIGQ 599
Query: 489 -SDLFKAGISENGI-----SYWLTSYAFSDIGLWFDKEVIGENPLENENFRKLSPLFYAK 542
+ + A I+ N + T + G + + + + E K SP+ Y
Sbjct: 600 YPETYSACIARNPVINIASMMGSTDMCMVETGFPYSNSCLPDLNVWEEMLDK-SPIKYIP 658
Query: 543 NVKAPLLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFKRGAHGHS 591
VK P+LL+ ED R P Q + +Y LK V + ++ + H S
Sbjct: 659 QVKTPVLLMLGQEDRRVPFKQGMEYYRALKARNVPVRLLLYPKSNHALS 707
>gb|AAG18962.1| (AE004997) Vng0409c [Halobacterium sp. NRC-1]
Length = 598
Score = 81.5 bits (198), Expect = 3e-14
Identities = 84/316 (26%), Positives = 139/316 (43%), Gaps = 24/316 (7%)
Query: 306 IAKGKHWIMGFDVDEKVVYLKETATRLRELYIWD---GEERQLTDYNGLIFSKLKTFEPK 362
+ +G W G D D V + AT +++ D G Q T+ K EP+
Sbjct: 294 VIRGLSW--GPDGDTLAVVVS-AATENPNVFVVDVATGAATQWTNAATAGIPKSTFREPE 350
Query: 363 HFKFKSID-LEIDGWYIKPELKEGEKAPVIVFVHGGPKGMYGYYFKYEMQLMASKGYYIV 421
++++ D EI + +P+ +G PVIV HGGP+G F Q GY +
Sbjct: 351 LVRYETFDGREIPALFTRPD-GDGPH-PVIVDFHGGPEGQRRPSFLSLRQYFVDNGYAVF 408
Query: 422 YVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGITGISYGGFM 481
N RGS+GY + R ++ D G+ E+ D +RV G SYGGFM
Sbjct: 409 EPNVRGSSGYGATYMNLDNVRNRMDAVADGKAGV-EWLTARTDIDADRVVAYGGSYGGFM 467
Query: 482 TNWALTQ-SDLFKAGISENGISYWLTSYAFSDIGLW---FDKEVIGENPLENENFRKLSP 537
+LT+ +L+ AG+ GI+ ++T + G W + G + E +SP
Sbjct: 468 VLASLTEYPELWAAGVDIVGIANFVT--FLENTGDWRREHRESEYGSLDADREFLESISP 525
Query: 538 LFYAKNVKAPLLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYIA--IFKRGAHGHSIRGS 595
A ++APLL++H D R P+ ++ +++ V + +F HG S R
Sbjct: 526 TNNADRIRAPLLVLHGANDPRVPVGEA---ERIVEQASAHVPVEKHVFDDEGHGFSKRA- 581
Query: 596 PRHRMKRYKLFMEFFE 611
++ Y+ ++F +
Sbjct: 582 --NKQAAYRAVVDFLD 595
>pir||D72636 probable acylamino-acid-releasing enzyme APE1547 - Aeropyrum pernix
(strain K1) >gi|5105232|dbj|BAA80546.1| (AP000061) 582aa
long hypothetical acylamino-acid-releasing enzyme
[Aeropyrum pernix]
Length = 582
Score = 81.1 bits (197), Expect = 3e-14
Identities = 62/202 (30%), Positives = 93/202 (45%), Gaps = 8/202 (3%)
Query: 389 PVIVFVHGGPKGMYGYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDF 448
P +V VHGGP + +A+ G+++V N RGS GY E++ L+++ +
Sbjct: 361 PTVVLVHGGPFAEDSDSWDTFAASLAAAGFHVVMPNYRGSTGYGEEWRLKIIGDPCGGEL 420
Query: 449 QDILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALT-QSDLFKAGISENGISYWLTS 507
+D+ + + + A + I G SYGG+MT ALT + LFKAG++ + W
Sbjct: 421 EDV-SAAARWARESGLA--SELYIMGYSYGGYMTLCALTMKPGLFKAGVAGASVVDWEEM 477
Query: 508 YAFSDIGLW-FDKEVIGENPLENENFRKLSPLFYAKNVKAPLLLIHSLEDYRCPLDQSLM 566
Y SD F +++ G + E R SP+ + +K PL LIH D R PL L
Sbjct: 478 YELSDAAFRNFIEQLTGGS---REIMRSRSPINHVDRIKEPLALIHPQNDSRTPLKPLLR 534
Query: 567 FYHVLKDLGKEVYIAIFKRGAH 588
L GK I H
Sbjct: 535 LMGELLARGKTFEAHIIPDAGH 556
>gb|AAC35353.1| (AF083393) outer membrane protein adhesin [Capnocytophaga
gingivalis]
Length = 237
Score = 80.4 bits (195), Expect = 6e-14
Identities = 58/225 (25%), Positives = 103/225 (45%), Gaps = 15/225 (6%)
Query: 372 EIDGWYIKP-ELKEGEKAPVIVFVHGGPKGM-----YGYYFKYEMQLMASKGYYIVYVNP 425
+++ W IKP + E +K P+++F + GP + + + ++A KGY ++ V+
Sbjct: 10 KLNAWMIKPSDFNENKKYPLLMFQYSGPGSQQVHNSFSGFDTFWYYMLAQKGYIVLCVDG 69
Query: 426 RGSNGYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGITGISYGGFMTNWA 485
RG+ F ++ G + +D + + + D++R+GI G S+GGFM +
Sbjct: 70 RGTGYKGAAFKKCTYKQLGKYELEDQVEAAKIVGNYK-YIDKDRIGIWGWSFGGFMASNC 128
Query: 486 LTQSDLFKAGISENGISYWLTSYAFSDIGLWFDKEVIGENPLEN-ENFRKLSPLFYAKNV 544
+ + ++FK I+ ++ W F D E + P EN E + SPL YAKN+
Sbjct: 129 ILRGEMFKMSIAVAPVTNW----RFYDT---VYTERYMQTPQENPEGYDNNSPLTYAKNL 181
Query: 545 KAPLLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFKRGAHG 589
LL+H D + S+ K+ AI+ HG
Sbjct: 182 NKKFLLVHGTADDNVHVQNSMRLIESFVQYDKQFEWAIYPDKNHG 226
>pir||T33751 hypothetical protein R11E3.8 - Caenorhabditis elegans
>gi|3800993|gb|AAC68993.1| (AF100669) contains
similarity to prolyl oligopeptidase family (Pfam:
Prolyl_oligopep.hmm, score: 15.06) [Caenorhabditis
elegans]
Length = 745
Score = 80.4 bits (195), Expect = 6e-14
Identities = 57/208 (27%), Positives = 99/208 (47%), Gaps = 13/208 (6%)
Query: 364 FKFKSIDLEIDGWYIKPEL---KEGEKAPVIVFVHGGPKGM-YGYYFKYEMQLMASKGYY 419
F ++ ++LE DG + L EG P++V HGGP G + + ++ + + GY
Sbjct: 484 FSWEFVNLERDGATYEGILIVPNEGNNLPMVVNPHGGPHGASMASWPRRDLTTLLNSGYA 543
Query: 420 IVYVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGITGISYGG 479
++ VN RGS G+ +DF + G D +D+ N + P+ R++V + G S+GG
Sbjct: 544 VLQVNFRGSLGFGDDFIRALPGNCGDMDVKDVHNAVLTVLDKNPRISRDKVVLFGGSHGG 603
Query: 480 FMTNWALTQ-SDLFKAGISENGISYWLTSYAFSDIGLWFDKEVIGENP--------LENE 530
F+ + + Q +K+ ++ N + T + +DI W E GE P + E
Sbjct: 604 FLVSHLIGQYPGFYKSCVALNPVVNIATMHDITDIPEWCYFEGTGEYPDWTKITTTEQRE 663
Query: 531 NFRKLSPLFYAKNVKAPLLLIHSLEDYR 558
SP+ + +N P LL+ +D R
Sbjct: 664 KMFNSSPIAHVENATTPYLLLIGEKDLR 691
>pir||S66261 X-Pro dipeptidyl-peptidase (EC 3.4.14.11) - Flavobacterium
meningosepticum >gi|577284|dbj|BAA07702.1| (D42121)
Dipeptidyl peptidase IV [Chryseobacterium
meningosepticum] >gi|1098018|prf||2115194A dipeptidyl
peptidase IV [Flavobacterium meningosepticum]
Length = 711
Score = 77.3 bits (187), Expect = 5e-13
Identities = 61/212 (28%), Positives = 103/212 (47%), Gaps = 24/212 (11%)
Query: 372 EIDGWYIKPE-LKEGEKAPVIVFVHGGP---------KGMYGYYFKYEMQLMASKGYYIV 421
+++ W IKP+ +K PV +F + GP G G +F ++A KGY +V
Sbjct: 472 QMNAWMIKPKNFDPAKKYPVFMFQYSGPGSQQVANSWDGGNGIWF----DMLAQKGYLVV 527
Query: 422 YVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGITGISYGGFM 481
V+ RG+ + + G + +D + + + + D+ R+GI G SYGG+M
Sbjct: 528 CVDGRGTGFRGTKYKKVTYKNLGKYEIEDQITAAK-WLGNQSYVDKSRIGIFGWSYGGYM 586
Query: 482 TNWALTQ-SDLFKAGISENGISYWLTSYAFSDIGLWFDKEVIGENPLENENFRKL-SPLF 539
+ A+T+ +D+FK GI+ ++ W F D ++ ++ + + P EN++ L SP
Sbjct: 587 ASLAMTKGADVFKMGIAVAPVTNW----RFYD-SIYTERFL--QTPQENKDGYDLNSPTT 639
Query: 540 YAKNVKAPLLLIHSLEDYRCPLDQSLMFYHVL 571
YAK +K LLIH D S+ F L
Sbjct: 640 YAKLLKGKFLLIHGTADDNVHFQNSMEFSEAL 671
>sp|P34422|YL31_CAEEL HYPOTHETICAL 86.0 KDA PROTEIN F44B9.1 IN CHROMOSOME III
>gi|630620|pir||S44807 F44B9.1 protein - Caenorhabditis
elegans >gi|388586|gb|AAA28026.1| (L23648) homology with
acylamino-acid-releasing enzyme; putative
[Caenorhabditis elegans]
Length = 761
Score = 76.9 bits (186), Expect = 7e-13
Identities = 69/233 (29%), Positives = 108/233 (45%), Gaps = 12/233 (5%)
Query: 390 VIVFVHGGPKGMYGYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQ 449
+IV VHGGPK Y F + ++GY ++ VN RGS G+ + G +
Sbjct: 452 MIVLVHGGPKARDHYGFSPMNAWLTNRGYSVLQVNFRGSTGFGKRLTNAGNGEWGRKMHF 511
Query: 450 DILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALT-QSDLFKAGISENGISYWLT-S 507
DIL+ + EF + A+R V + G SYGG+ T ALT F G+ G S ++
Sbjct: 512 DILDAV-EFAVSKGIANRSEVAVMGGSYGGYETLVALTFTPQTFACGVDIVGPSNLISLV 570
Query: 508 YAFSDIGLWFDKEVI---GENPLENENFRKL---SPLFYAKNVKAPLLLIHSLEDYRCPL 561
A L F K++I G + + E + L SPLF+A V P+++I D R
Sbjct: 571 QAIPPYWLGFRKDLIKMVGADISDEEGRQSLQSRSPLFFADRVTKPIMIIQGANDPRVKQ 630
Query: 562 DQSLMFYHVLKDLGKEVYIAIFKRGAHGHSIRGSPRHRMKRYKLFMEFFERKL 614
+S F L+ K + + GH +R P++ M+++ F ++ L
Sbjct: 631 AESDQFVAALEK--KHIPVTYLLYPDEGHGVR-KPQNSMEQHGHIETFLQQCL 680
>pir||T35975 probable acyl-peptide hydrolase - Streptomyces coelicolor
>gi|4154083|emb|CAA22736.1| (AL035161) putative
acyl-peptide hydrolase [Streptomyces coelicolor A3(2)]
Length = 655
Score = 76.5 bits (185), Expect = 9e-13
Identities = 62/242 (25%), Positives = 103/242 (41%), Gaps = 17/242 (7%)
Query: 384 EGEKAPVIVFVHGGPKGMYGYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERT 443
+GE P +++ HGGP E+ S+G + VN GS+G+ ++ R+ E+
Sbjct: 413 DGELPPYVIWAHGGPTSRSPLVLDLEIAYFTSRGIGVAEVNYGGSSGHGREYRNRLREQW 472
Query: 444 GLEDFQDILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQSDLFKAGISENGI-- 501
G+ D +D + E ADR R+ + G S GG+ + +L +D++ G I
Sbjct: 473 GVVDVEDCA-AVALALADEGTADRARLAVRGGSAGGWTSAASLATTDVYACGTISYPILD 531
Query: 502 -SYWLTSYAFSDIGLWFDKEVIGENPLENENFRKLSPLFYAKNVKAPLLLIHSLEDYRCP 560
+ W T D + + +IG + + SP +A+ V AP LL+ L+D CP
Sbjct: 532 LTGWGTGET-HDFESQYLESLIGPYAEVPDRYTDRSPAEHAERVTAPFLLLQGLDDVICP 590
Query: 561 LDQSLMFYHVLKDLG-KEVYIAIFKRGAHGHSIRGSPRHRMKRYKLFMEFFERKLKKYEE 619
Q F + G Y+A G H +R + + E +L Y +
Sbjct: 591 PVQCERFLDRMAGRGVPHAYLAFEGEG-----------HGFRRAETMVRALEAELSLYAQ 639
Query: 620 GF 621
F
Sbjct: 640 VF 641
>emb|CAB39035.2| (AL034559) putative acylaminoacyl-peptidase [Plasmodium falciparum]
Length = 1074
Score = 76.1 bits (184), Expect = 1e-12
Identities = 66/244 (27%), Positives = 116/244 (47%), Gaps = 22/244 (9%)
Query: 354 SKLKTFEPKHFKFKSIDLEIDGWYIKPELKEGEKAPVIVFVHGGPKGMYGYYFKYEMQLM 413
S L + K+F + +L + K +L+ +I+++HGGP + +K
Sbjct: 816 SFLNDIQEKNFSLSNFNL-----FNKKKLRN-----LILYIHGGPYSIILNEYKNIFIFF 865
Query: 414 ASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGIT 473
A+ G+ ++ VN GS +S + +E DI+N ++F D E + +
Sbjct: 866 AASGFDVLCVNYIGSLTFSNKLNILSGHINSIE-IDDIINIFKDFVNYF--GDYENIYLY 922
Query: 474 GISYGGFMTNWALTQ-SDLFKAGISENGISYWLTSYAFSDIGLWF-----DKEVIGENPL 527
G SYG F + LT+ + LFK+ NG+ W+ S SD+ +F +K + L
Sbjct: 923 GGSYGAFASCALLTKYNSLFKSACIINGVYEWILSTYSSDVPDFFLNITRNKFSEYDYNL 982
Query: 528 ENENFRKL---SPLFYAKNVKAPLLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFK 584
E++ L SP+ YA N+ +P+L+I S +D R S+ Y+ L+ L K+ + +F+
Sbjct: 983 SKEDYTLLYDMSPINYAHNISSPILIICSKDDKRVSYHNSIALYNKLRALKKKCKLFLFQ 1042
Query: 585 RGAH 588
H
Sbjct: 1043 NTNH 1046
>gb|AAG29766.1|AF221634_1 (AF221634) dipeptidyl peptidase 8 [Homo sapiens]
Length = 882
Score = 75.7 bits (183), Expect = 1e-12
Identities = 65/249 (26%), Positives = 112/249 (44%), Gaps = 17/249 (6%)
Query: 361 PKHFKFKSID-LEIDGWYIKP-ELKEGEKAPVIVFVHGGPK-GMYGYYFK----YEMQLM 413
P+ F F+S + G KP +L+ G+K P ++F++GGP+ + FK + + +
Sbjct: 617 PEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTL 676
Query: 414 ASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGIT 473
AS GY +V ++ RGS F + G + D + G++ D +RVGI
Sbjct: 677 ASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIH 736
Query: 474 GISYGGFMTNWALTQ-SDLFKAGISENGISYWLTSYAFSDIGLWFDKEVIGENPLENENF 532
G SYGG+++ AL Q SD+F+ I+ ++ W+ F D G + + +G + +
Sbjct: 737 GWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWI----FYDTG--YTERYMGHPDQNEQGY 790
Query: 533 RKLSPLFYAKNVKAP---LLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFKRGAHG 589
S A+ + LLL+H D + + L GK + I+ + H
Sbjct: 791 YLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHS 850
Query: 590 HSIRGSPRH 598
+ S H
Sbjct: 851 IRVPESGEH 859
>gb|AAF52407.2| (AE003614) CG11319 gene product [Drosophila melanogaster]
Length = 988
Score = 73.7 bits (178), Expect = 6e-12
Identities = 69/251 (27%), Positives = 106/251 (41%), Gaps = 24/251 (9%)
Query: 377 YIKPELKEGE--KAPVIVFVHGGPKGMY---GYYFKYEMQLMASKGYYIVYVNPRGSNGY 431
Y+ P L+E E + P I+ V+ GP ++ + L SK Y +V ++ RGS G
Sbjct: 727 YLPPVLREDEITRYPTILHVYSGPGSQLVTDHWHVDWNTYLSGSKDYIVVEIDGRGSAGQ 786
Query: 432 SEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALT-QSD 490
V +R G + D L E D R+G+ G SYGG+ AL Q
Sbjct: 787 GYQLLHEVYKRLGSVEVSDQLEVSEYLRDNLHFIDSRRMGVWGWSYGGYTAALALAGQQS 846
Query: 491 LFKAGISENGISYW-LTSYAFSDIGLWFDKEVIGENPLENENFRKLSPLFYAKNVK-APL 548
+F+ GIS + ++ W L +++ L F E + K Y N++
Sbjct: 847 IFQCGISVSPVTNWKLYDSTYAERYLSFPNVTDNYKGYEESDLSK-----YVDNLRDRQF 901
Query: 549 LLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFKRGAH---GHSIRGSPRHRMKRYKL 605
LL+H D + QS++ L G ++K+ + GHS+ G RH Y+
Sbjct: 902 LLVHGTADDNVHVQQSMVLARSLTSKG-----VLYKQQIYPDEGHSLSGVKRH---LYRS 953
Query: 606 FMEFFERKLKK 616
FFE KK
Sbjct: 954 MTAFFEDCFKK 964
>gb|AAC46184.1| (AF026511) dipeptidyl peptidase IV [Porphyromonas gingivalis]
Length = 723
Score = 72.6 bits (175), Expect = 1e-11
Identities = 75/279 (26%), Positives = 120/279 (42%), Gaps = 25/279 (8%)
Query: 339 DGEERQLTDYNGLIFSKLKTFE--PKHFKFKSID--LEIDGWYIKP-ELKEGEKAPVIVF 393
D +E + + N + +LK + PK F LE++ W +KP + PV++
Sbjct: 450 DAKELRTLEDNVALRERLKAYRYNPKEFTIIKTQSGLELNAWIVKPIDFDPSRHYPVLMV 509
Query: 394 VHGGPKGMY---GYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQD 450
+ GP Y F +E L ASKGY + V+ RG+ E++ + G+ + D
Sbjct: 510 QYSGPNSQQVLDRYSFDWEHYL-ASKGYVVACVDGRGTGARGEEWRKCTYMQLGVFESDD 568
Query: 451 ILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQSD-LFKAGISENGISYWLTSYA 509
+ +L P D R+GI G SYGG+ T +L + + FKAGI+ ++ W
Sbjct: 569 QIAAATAIGQL-PYVDAARIGIWGWSYGGYTTLMSLCRGNGTFKAGIAVAPVADW----R 623
Query: 510 FSDIGLWFDKEVIGENPLEN-ENFRKLSPLFYAKNVKAPLLLIHSLEDYRCPLDQSLMFY 568
F D E P EN ++ S L A ++ LL++ D L +++F
Sbjct: 624 FYDS---VYTERFMRTPKENASGYKMSSALDVASQLQGNLLIVSGSADDNVHLQNTMLFT 680
Query: 569 HVLKDLGKEVYIAIFKRGAHGHSIRGSPRHRMKRYKLFM 607
L +AI+ HSI G RY L++
Sbjct: 681 EALVQANIPFDMAIYM--DKNHSIYGG----NTRYHLYI 713
>pir||JC5142 X-Pro dipeptidyl-peptidase (EC 3.4.14.11) - Xanthomonas maltophilia
>gi|1753197|dbj|BAA11872.1| (D83263) dipeptidyl
peptidase IV [Stenotrophomonas maltophilia]
Length = 741
Score = 72.2 bits (174), Expect = 2e-11
Identities = 66/252 (26%), Positives = 110/252 (43%), Gaps = 31/252 (12%)
Query: 378 IKPE-LKEGEKAPVIVFVHGGPK---------GMYGYYFKYEMQLMASKGYYIVYVNPRG 427
IKP ++ PV V+V+GGP G + F Q +A +GY + ++ RG
Sbjct: 506 IKPAGFDPAKRYPVAVYVYGGPASQTVTDSWPGRGDHLFN---QYLAQQGYVVFSLDNRG 562
Query: 428 SNGYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGITGISYGGFMTNWALT 487
+ DF + + G + D L G+ + K +P D R+G+ G S GG+MT L
Sbjct: 563 TPRRGRDFGGALYGKQGTVEVADQLRGVA-WLKQQPWVDPARIGVQGWSNGGYMTLMLLA 621
Query: 488 Q-SDLFKAGISENGISYWLTSYAFSDIGLWFDK--EVIGENPLENE-NFRKLSPLFYAKN 543
+ SD + G++ ++ W GL+ E + P N+ +R+ L + +
Sbjct: 622 KASDSYACGVAGAPVTDW---------GLYDSHYTERYMDLPARNDAGYREARVLTHIEG 672
Query: 544 VKAPLLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFKRGAHGHSIRGSPRHRMKRY 603
+++PLLLIH + D S L+ G+ + + HG S + RY
Sbjct: 673 LRSPLLLIHGMADDNVLFTNSTSLMSALQKRGQPFELMTYPGAKHGL----SGADALHRY 728
Query: 604 KLFMEFFERKLK 615
++ F R LK
Sbjct: 729 RVAEAFLGRCLK 740
>gb|AAD52012.1|AF082514_1 (AF082514) Tri r 4 allergen [Trichophyton rubrum]
Length = 726
Score = 71.0 bits (171), Expect = 4e-11
Identities = 90/369 (24%), Positives = 155/369 (41%), Gaps = 32/369 (8%)
Query: 235 DGKNILLYGKPEKKYMSEHDKLYIYD----GEVKGIMDSIDREAGQAK-IKDGK-VYFTL 288
DGK I K Y S+ ++I + V+ I + DR K DG+ +Y T
Sbjct: 296 DGKRIAYLQMAAKNYESDRRVIHIAEVGTNKPVQRIASNWDRSPEAVKWSSDGRTLYVTA 355
Query: 289 YEEGSVNLYLWDGDIKEIAK-------GKHWIMGFDVDEKVVYLKETATRLRELY---IW 338
+ + L+ D ++ K G F K V + + LY
Sbjct: 356 EDHATGKLFTLPADARDNHKPAVVKHDGSVSSFYFIGSSKSVLISGNSLWSNALYQVATP 415
Query: 339 DGEERQLTDYNGLIFSKLKTFEPKHFKFKSID---LEIDGWYIKPELKEGEKA-PVIVFV 394
D R+L Y +LK P + +D +I W +KP + K P+ +
Sbjct: 416 DRPNRKLF-YANEHDPELKGLGPNDIEPLWVDGARTKIHSWIVKPTGFDKNKVYPLAFLI 474
Query: 395 HGGPKGMYG--YYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQDIL 452
HGGP+G +G + ++ ++ A +GY +V NP GS G+ + + G ++D++
Sbjct: 475 HGGPQGSWGDNWSTRWNPRVWADQGYVVVAPNPTGSTGFGQKLTDDITNDWGGAPYKDLV 534
Query: 453 NGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQSDL---FKAGISENGISYWLTSYA 509
E D + G S+GGFM NW Q DL FKA +S +G ++ +S
Sbjct: 535 KIWEHVHDHIKYIDTDNGIAAGASFGGFMVNWIQGQ-DLGRKFKALVSHDG-TFVGSSKI 592
Query: 510 FSDIGLWFDKEVIGENPLENENFRK---LSPLFYAKNVKAPLLLIHSLEDYRCPLDQSLM 566
+D + + + G +N+ + P AK P L++H+ D+R + + +
Sbjct: 593 GTDELFFIEHDFNGTFFEARQNYDRWDCSKPELVAK-WSTPQLVVHNDFDFRLSVAEGVG 651
Query: 567 FYHVLKDLG 575
++VL++ G
Sbjct: 652 LFNVLQEKG 660
>dbj|BAA28265.1| (AB008194) DPP IV [Porphyromonas gingivalis]
Length = 723
Score = 70.2 bits (169), Expect = 6e-11
Identities = 73/264 (27%), Positives = 115/264 (42%), Gaps = 22/264 (8%)
Query: 341 EERQLTDYNGLIFSKLKTFEPKHFKFKSID----LEIDGWYIKP-ELKEGEKAPVIVFVH 395
E R L D N + +LK + +F +I LE++ W +KP + PV++ +
Sbjct: 453 ELRTLED-NVALRERLKAYRYNPKEFTTIKTQSGLELNAWIVKPIDFDPSRHYPVLMVQY 511
Query: 396 GGPKGMY---GYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQDIL 452
GP Y F +E L ASKGY + V+ RG+ E++ + G+ + D +
Sbjct: 512 SGPNSQQVLDRYSFDWEHYL-ASKGYVVACVDGRGTGARGEEWRKCTYMQLGVFESDDQI 570
Query: 453 NGIEEFFKLEPQADRERVGITGISYGGFMTNWALTQSD-LFKAGISENGISYWLTSYAFS 511
+L P D R+GI G SYGG+ T +L + + FKAGI+ ++ W F
Sbjct: 571 AAATAIGQL-PYVDAARIGIWGWSYGGYTTLMSLCRGNGTFKAGIAVAPVADW----RFY 625
Query: 512 DIGLWFDKEVIGENPLEN-ENFRKLSPLFYAKNVKAPLLLIHSLEDYRCPLDQSLMFYHV 570
D E P EN ++ S L A ++ LL++ D L +++F
Sbjct: 626 DS---VYTERFMRTPKENASGYKMSSALDVASQLQGNLLIVSGSADDNVHLQNTMLFTEA 682
Query: 571 LKDLGKEVYIAIFKRGAHGHSIRG 594
L +AI+ HSI G
Sbjct: 683 LVQANIPFDMAIYM--DKNHSIYG 704
>gb|AAG29769.1|AF221637_1 (AF221637) dipeptidyl peptidase 8 [Homo sapiens]
Length = 360
Score = 69.9 bits (168), Expect = 9e-11
Identities = 47/153 (30%), Positives = 80/153 (51%), Gaps = 8/153 (5%)
Query: 361 PKHFKFKSID-LEIDGWYIKP-ELKEGEKAPVIVFVHGGPK-GMYGYYFK----YEMQLM 413
P+ F F+S + G KP +L+ G+K P ++F++GGP+ + FK + + +
Sbjct: 201 PEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTL 260
Query: 414 ASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEFFKLEPQADRERVGIT 473
AS GY +V ++ RGS F + G + D + G++ D +RVGI
Sbjct: 261 ASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIH 320
Query: 474 GISYGGFMTNWALTQ-SDLFKAGISENGISYWL 505
G SYGG+++ AL Q SD+F+ I+ ++ W+
Sbjct: 321 GWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWI 353
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.320 0.140 0.424
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 255816283
Number of Sequences: 2977
Number of extensions: 11896204
Number of successful extensions: 27521
Number of sequences better than 1.0e-10: 48
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 27359
Number of HSP's gapped (non-prelim): 82
length of query: 632
length of database: 189,106,746
effective HSP length: 54
effective length of query: 578
effective length of database: 156,788,448
effective search space: 90623722944
effective search space used: 90623722944
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 168 (69.9 bits)