BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1434 (map) DE:methionine aminopeptidase (map) (EC 3.4.11.18)
(295 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||C75054 methionyl aminopeptidase (EC 3.4.11.18) map PAB1434 ... 584 e-166
sp|O58362|AMPM_PYRHO METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE ... 549 e-155
sp|P56218|AMPM_PYRFU METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE ... 517 e-146
sp|O27355|AMPM_METTH METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE ... 303 1e-81
gi|11499425 methionyl aminopeptidase (map) [Archaeoglobus fulgid... 285 4e-76
sp|Q58725|AMPM_METJA METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE ... 282 3e-75
sp|P95963|AMPM_SULSO METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE ... 242 5e-63
gb|AAK40454.1| Methionine aminopeptidase 2 [Sulfolobus solfatari... 242 5e-63
emb|CAC12559.1| (AL445067) methionyl aminopeptidase related prot... 237 1e-61
pir||C72712 probable methionine aminopeptidase APE1114 - Aeropyr... 226 3e-58
gb|AAG20067.1| (AE005086) methionyl aminopeptidase; Map [Halobac... 206 2e-52
pir||T39431 probable methionine metallopeptidase - fission yeast... 178 5e-44
sp|P22624|AMPM_METFE PROBABLE METHIONINE AMINOPEPTIDASE (MAP) (P... 176 3e-43
gb|AAG33978.1|AF250964_1 (AF250964) methionine aminopeptidase-li... 175 8e-43
pir||T00698 methionyl aminopeptidase (EC 3.4.11.18) F6E13.31 - A... 175 8e-43
pir||T47823 hypothetical protein F24G16.260 - Arabidopsis thalia... 174 1e-42
gb|AAG34551.1|AF300880_1 (AF300880) putative methionine aminopep... 174 1e-42
gi|5803092 methionine aminopeptidase; eIF-2-associated p67 [Homo... 171 7e-42
pdb|1BN5| Human Methionine Aminopeptidase 2 >gi|5821858|pdb|1B... 171 7e-42
pdb|1B59|A Chain A, Complex Of Human Methionine Aminopeptidase-2... 171 7e-42
sp|P38062|AMP2_RAT METHIONINE AMINOPEPTIDASE 2 (METAP 2) (PEPTID... 169 3e-41
pir||A46702 methionyl aminopeptidase (EC 3.4.11.18) 2 - rat >gi|... 169 3e-41
gi|9789873 methionine aminopeptidase 2; initiation factor 2-asso... 169 4e-41
emb|CAB55167.1| (AL117205) contains similarity to Pfam domain: P... 164 1e-39
gb|AAC05144.1| (AF049912) methionine aminopeptidase [Drosophila ... 155 4e-37
gb|AAF52807.1| (AE003626) und gene product [Drosophila melanogas... 155 4e-37
pir||S45411 methionyl aminopeptidase (EC 3.4.11.18) MAP2 - yeast... 152 5e-36
sp|P38174|AMP2_YEAST METHIONINE AMINOPEPTIDASE 2 (METAP 2) (PEPT... 152 5e-36
gi|6319380 methionine aminopeptidase 2; Map2p [Saccharomyces cer... 152 5e-36
sp|P56102|AMPM_HELPY METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE ... 113 3e-24
sp|Q9ZJT0|AMPM_HELPJ METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE ... 110 2e-23
pir||T51151 probable nuclear DNA-binding protein G2p [imported] ... 109 5e-23
pir||T02069 probable DNA-binding protein GBP16 - rice >gi|251154... 108 7e-23
gi|6755100 proliferation-associated protein 1 [Mus musculus] >gi... 108 1e-22
gb|AAF50751.1| (AE003565) CG10576 gene product [Drosophila melan... 107 2e-22
sp|O66489|AMPM_AQUAE METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE ... 106 4e-22
gb|AAB03665.1| (U61403) PrlA [Dictyostelium discoideum] 105 6e-22
gi|5453842 proliferation-associated 2G4, 38kD [Homo sapiens] >gi... 105 6e-22
gb|AAD05561.1| (AF104670) cell cycle protein [Homo sapiens] 105 6e-22
gi|11435123 proliferation-associated 2G4, 38kD [Homo sapiens] 105 6e-22
gb|AAC34392.1| (AF056116) PAS1 [Takifugu rubripes] 104 1e-21
gb|AAF39984.1| (AC006696) contains similarity to Pfam family PF0... 104 1e-21
pir||E69810 methionine aminopeptidase homolog yflG - Bacillus su... 100 2e-20
pir||T50575 methionyl aminopeptidase (EC 3.4.11.18) [imported] -... 99 7e-20
gb|AAF04629.2|AF099106_1 (AF099106) p45 [Leishmania major] 98 1e-19
pir||A81262 methionyl aminopeptidase (EC 3.4.11.18) Cj1651c [imp... 98 1e-19
gb|AAF91445.1|AF281652_1 (AF281652) putative DNA binding protein... 98 1e-19
pir||F72247 methionine aminopeptidase - Thermotoga maritima (str... 98 2e-19
dbj|BAB03321.1| (AB035448) methionin aminopeptidase [Staphylococ... 97 2e-19
sp|P19994|AMPM_BACSU METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE ... 95 8e-19
pir||C75410 methionine aminopeptidase - Deinococcus radiodurans ... 95 8e-19
pir||S54181 p38-2G4 protein - mouse >gi|790470|emb|CAA59260.1| (... 95 1e-18
emb|CAB16790.1| (Z99707) methionyl aminopeptidase-like protein [... 94 2e-18
gb|AAG33977.1|AF250963_1 (AF250963) methionine aminopeptidase-li... 94 2e-18
gb|AAD00646.1| (U87954) erbB3 binding protein EBP1 [Homo sapiens] 92 5e-18
gb|AAG33975.1|AF250961_1 (AF250961) methionine aminopeptidase-li... 92 7e-18
dbj|BAA95761.1| (AB028607) methionine aminopeptidase-like protei... 92 9e-18
gb|AAG09564.1|AC011810_23 (AC011810) Putative methionine aminope... 91 1e-17
pir||C83301 probable methionine aminopeptidase PA2748 [imported]... 91 2e-17
sp|P53579|AMP1_SYNY3 PUTATIVE METHIONINE AMINOPEPTIDASE A (MAP) ... 89 5e-17
sp|P53581|AMP3_SYNY3 PUTATIVE METHIONINE AMINOPEPTIDASE C (MAP) ... 89 5e-17
sp|Q9Z9J4|AMPM_BACHD METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE ... 89 5e-17
gb|AAG33976.1|AF250962_1 (AF250962) methionine aminopeptidase-li... 89 5e-17
sp|Q09184|CDB4_SCHPO CURVED DNA-BINDING PROTEIN (42 KD PROTEIN) ... 89 5e-17
pir||D83189 methionine aminopeptidase PA3657 [imported] - Pseudo... 89 6e-17
sp|O51132|AMPM_BORBU METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE ... 89 8e-17
pir||T34903 methionine aminopeptidase - Streptomyces coelicolor ... 88 1e-16
gi|6323273 methionine aminopeptidase; Map1p [Saccharomyces cerev... 87 2e-16
sp|O33343|AMPM_MYCTU METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE ... 87 2e-16
sp|P53580|AMP2_SYNY3 PUTATIVE METHIONINE AMINOPEPTIDASE B (MAP) ... 87 2e-16
gb|AAF52949.1| (AE003628) CG5188 gene product [Drosophila melano... 85 7e-16
pir||A70823 probable methionine amino peptidase - Mycobacterium ... 84 2e-15
pir||T45391 methionine aminopeptidase [imported] - Mycobacterium... 83 5e-15
sp|Q9Z6Q0|AMPM_CHLPN METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE ... 83 5e-15
pir||A81531 methionine aminopeptidase CP0844 [imported] - Chlamy... 83 5e-15
sp|P53582|AMP1_HUMAN PUTATIVE METHIONINE AMINOPEPTIDASE 1 (METAP... 82 8e-15
sp|P07906|AMPM_ECOLI METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE ... 81 1e-14
sp|O83814|AMPM_TREPA METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE ... 80 3e-14
pdb|2MAT|A Chain A, E.Coli Methionine Aminopeptidase At 1.9 Angs... 80 4e-14
pdb|1C22|A Chain A, E. Coli Methionine Aminopeptidase: Trifluoro... 80 4e-14
pdb|3MAT|A Chain A, E.Coli Methionine Aminopeptidase Transition-... 80 4e-14
pdb|4MAT|A Chain A, E.Coli Methionine Aminopeptidase His79ala Mu... 80 4e-14
pir||D82097 methionine aminopeptidase VC2261 [imported] - Vibrio... 78 9e-14
sp|Q9ZCD3|AMPM_RICPR METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE ... 78 1e-13
sp|P44421|AMPM_HAEIN METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE ... 76 5e-13
gb|AAB82638.1| (AC002387) putative methionine aminopeptidase [Ar... 76 6e-13
gb|AAF56327.1| (AE003749) CG13630 gene product [Drosophila melan... 75 8e-13
pir||E82917 methionine aminopeptidase (map) UU252 [imported] - U... 75 1e-12
sp|P57324|AMPM_BUCAI METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE ... 73 3e-12
pir||E82845 methionine aminopeptidase XF0111 [imported] - Xylell... 73 4e-12
pir||T35553 methionine aminopeptidase - Streptomyces coelicolor ... 71 1e-11
sp|O84859|AMPM_CHLTR METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE ... 71 1e-11
pir||T40384 probable methionine aminopeptidase 1 - fission yeast... 71 2e-11
pir||G81724 methionine aminopeptidase TC0240 [imported] - Chlamy... 71 2e-11
pir||C75134 x-pro aminopeptidase (pepq-3) PAB1781 - Pyrococcus a... 71 2e-11
>pir||C75054 methionyl aminopeptidase (EC 3.4.11.18) map PAB1434 - Pyrococcus
abyssi (strain Orsay) >gi|5458841|emb|CAB50328.1|
(AJ248287) methionine aminopeptidase (map) (EC
3.4.11.18) [Pyrococcus abyssi]
Length = 295
Score = 584 bits (1489), Expect = e-166
Identities = 295/295 (100%), Positives = 295/295 (100%)
Query: 1 MDVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFPVNLSLNEIA 60
MDVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFPVNLSLNEIA
Sbjct: 1 MDVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFPVNLSLNEIA 60
Query: 61 AHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESAIS 120
AHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESAIS
Sbjct: 61 AHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESAIS 120
Query: 121 VARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYRPHDNYKLRE 180
VARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYRPHDNYKLRE
Sbjct: 121 VARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYRPHDNYKLRE 180
Query: 181 GDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRMVQARFLLAKIKREYKTLPFAYRWL 240
GDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRMVQARFLLAKIKREYKTLPFAYRWL
Sbjct: 181 GDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRMVQARFLLAKIKREYKTLPFAYRWL 240
Query: 241 QGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIVEKDSVIVTTE 295
QGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIVEKDSVIVTTE
Sbjct: 241 QGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIVEKDSVIVTTE 295
>sp|O58362|AMPM_PYRHO METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE M)
>gi|7435554|pir||C71107 probable methionyl
aminopeptidase - Pyrococcus horikoshii
>gi|3257034|dbj|BAA29717.1| (AP000003) 295aa long
hypothetical methionyl aminopeptidase [Pyrococcus
horikoshii]
Length = 295
Score = 549 bits (1400), Expect = e-155
Identities = 271/295 (91%), Positives = 286/295 (96%)
Query: 1 MDVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFPVNLSLNEIA 60
MDVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIE RI+ELG KPAFP NLSLNE+A
Sbjct: 1 MDVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIESRIVELGGKPAFPANLSLNEVA 60
Query: 61 AHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESAIS 120
AHYTPYKGD+T LKEGDYLKID+GVHIDGYIADTAVTVRVGM+ D+LMEAA+EALESAIS
Sbjct: 61 AHYTPYKGDQTVLKEGDYLKIDLGVHIDGYIADTAVTVRVGMDFDELMEAAKEALESAIS 120
Query: 121 VARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYRPHDNYKLRE 180
VARAGVE+KELG+AIE+EIRKRGFNPIVNLSGHKIERYKLHAG+SIPNIYRPHDNY L+E
Sbjct: 121 VARAGVEVKELGKAIENEIRKRGFNPIVNLSGHKIERYKLHAGVSIPNIYRPHDNYVLQE 180
Query: 181 GDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRMVQARFLLAKIKREYKTLPFAYRWL 240
GDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRM QARFLLAKIKREYKTLPFAYRWL
Sbjct: 181 GDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRMAQARFLLAKIKREYKTLPFAYRWL 240
Query: 241 QGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIVEKDSVIVTTE 295
QGEMPEGQLKLALR+LE+SGALYGYPVLREIR G+VTQFEHTIIVEKDSV VTTE
Sbjct: 241 QGEMPEGQLKLALRSLERSGALYGYPVLREIRGGMVTQFEHTIIVEKDSVTVTTE 295
>sp|P56218|AMPM_PYRFU METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE M)
>gi|7435553|pir||JC5671 methionyl aminopeptidase (EC
3.4.11.18) type II [validated] - Pyrococcus furiosus
>gi|2392623|pdb|1XGS|A Chain A, Methionine
Aminopeptidase From Hyperthermophile Pyrococcus Furiosus
>gi|2392624|pdb|1XGS|B Chain B, Methionine
Aminopeptidase From Hyperthermophile Pyrococcus Furiosus
>gi|2982138|pdb|1XGM|A Chain A, Methionine
Aminopeptidase From Hyperthermophile Pyrococcus Furiosus
>gi|2982139|pdb|1XGM|B Chain B, Methionine
Aminopeptidase From Hyperthermophile Pyrococcus Furiosus
>gi|2982140|pdb|1XGN|A Chain A, Methionine
Aminopeptidase From Hyperthermophile Pyrococcus Furiosus
>gi|2982141|pdb|1XGN|B Chain B, Methionine
Aminopeptidase From Hyperthermophile Pyrococcus Furiosus
>gi|2982142|pdb|1XGO| Methionine Aminopeptidase From
Hyperthermophile Pyrococcus Furiosus
Length = 295
Score = 517 bits (1318), Expect = e-146
Identities = 253/295 (85%), Positives = 278/295 (93%)
Query: 1 MDVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFPVNLSLNEIA 60
MD +KL++AG+IAKKVRE+A+KLA+PG+ LLELAE IE I+ELG KPAFPVNLS+NEIA
Sbjct: 1 MDTEKLMKAGEIAKKVREKAIKLARPGMLLLELAESIEKMIMELGGKPAFPVNLSINEIA 60
Query: 61 AHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESAIS 120
AHYTPYKGD T LKEGDYLKID+GVHIDG+IADTAVTVRVGMEED+LMEAA+EAL +AIS
Sbjct: 61 AHYTPYKGDTTVLKEGDYLKIDVGVHIDGFIADTAVTVRVGMEEDELMEAAKEALNAAIS 120
Query: 121 VARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYRPHDNYKLRE 180
VARAGVEIKELG+AIE+EIRKRGF PIVNLSGHKIERYKLHAGISIPNIYRPHDNY L+E
Sbjct: 121 VARAGVEIKELGKAIENEIRKRGFKPIVNLSGHKIERYKLHAGISIPNIYRPHDNYVLKE 180
Query: 181 GDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRMVQARFLLAKIKREYKTLPFAYRWL 240
GDVFAIEPFAT GAGQVIEVPPTLIYMYVRD PVR+ QARFLLAKIKREY TLPFAYRWL
Sbjct: 181 GDVFAIEPFATIGAGQVIEVPPTLIYMYVRDVPVRVAQARFLLAKIKREYGTLPFAYRWL 240
Query: 241 QGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIVEKDSVIVTTE 295
Q +MPEGQLKLAL+TLEK+GA+YGYPVL+EIRNG+V QFEHTIIVEKDSVIVTTE
Sbjct: 241 QNDMPEGQLKLALKTLEKAGAIYGYPVLKEIRNGIVAQFEHTIIVEKDSVIVTTE 295
>sp|O27355|AMPM_METTH METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE M)
>gi|7435555|pir||C69039 methionine aminopeptidase -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2622402|gb|AAB85776.1| (AE000894) methionine
aminopeptidase [Methanobacterium thermoautotrophicum]
Length = 299
Score = 303 bits (769), Expect = 1e-81
Identities = 148/296 (50%), Positives = 208/296 (70%), Gaps = 4/296 (1%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFPVNLSLNEIAAH 62
++ ++AGKI KVR EA + + G+ ++EL +E RIIE G +PAFP N+S+NE+ AH
Sbjct: 5 IESYLKAGKIVSKVRREAAGIIRDGLPIIELVNYVEDRIIEEGGRPAFPCNVSVNEVTAH 64
Query: 63 YTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEED---DLMEAAREALESAI 119
YT GD++ + +GD +K+D+G H+DG+IADTA+TV VG +D +M+AAREALE+AI
Sbjct: 65 YTSPPGDDSVIGDGDLVKLDLGAHVDGFIADTAITVPVGDVDDKCHQMMDAAREALENAI 124
Query: 120 SVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYRPHDNYKLR 179
S RAGVE+ E+GR IE+ I G NP+ NL+GH +ER+ LH+G+SIPNI + ++L
Sbjct: 125 STIRAGVEVGEIGRVIEETIHSHGMNPVSNLTGHSMERWILHSGLSIPNI-NERNTHQLE 183
Query: 180 EGDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRMVQARFLLAKIKREYKTLPFAYRW 239
EGDV AIEPFAT G G V ++P T I+ ++R+ P+R+V AR +L KI+ EY LPFA RW
Sbjct: 184 EGDVLAIEPFATDGVGLVTDMPQTYIFRFLRERPLRLVHARRVLGKIREEYHALPFAQRW 243
Query: 240 LQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIVEKDSVIVTTE 295
L+ +L ++R L +S A+Y Y VLRE +V Q+EHT+IVE+D V TE
Sbjct: 244 LEEYFDAKRLNASMRMLIQSRAIYPYHVLREKSGAMVAQWEHTVIVEEDGCTVITE 299
>gi|11499425 methionyl aminopeptidase (map) [Archaeoglobus fulgidus]
>gi|3122371|sp|O28438|AMPM_ARCFU METHIONINE
AMINOPEPTIDASE (MAP) (PEPTIDASE M)
>gi|7435552|pir||G69479 methionyl aminopeptidase (map)
homolog - Archaeoglobus fulgidus
>gi|2648708|gb|AAB89413.1| (AE000976) methionyl
aminopeptidase (map) [Archaeoglobus fulgidus]
Length = 291
Score = 285 bits (722), Expect = 4e-76
Identities = 154/292 (52%), Positives = 197/292 (66%), Gaps = 7/292 (2%)
Query: 4 DKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFPVNLSLNEIAAHY 63
+KLIEAGKI K+ EA + PGV +LE+AE +E RIIELGAKPAFP N+S+N AAH+
Sbjct: 7 EKLIEAGKILKQAVNEAAEKIAPGVKILEVAEFVENRIIELGAKPAFPANISINSDAAHF 66
Query: 64 TPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESAISVAR 123
TP K DE T KEGD +K+D+G HIDGYIAD AVTV +G + +L++AA+EALE+A+ V R
Sbjct: 67 TPKKNDERTFKEGDVVKLDVGAHIDGYIADMAVTVDLG-DNTELVKAAKEALEAAMEVVR 125
Query: 124 AGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYRPHDNYKLREGDV 183
AGV + E+G+AIED I GF PIVNL+GH + Y HA SI N Y L EG V
Sbjct: 126 AGVSVSEIGKAIEDAITNYGFKPIVNLTGHGLLPYLNHAPPSIYN-YATEKGVTLEEGMV 184
Query: 184 FAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRMVQARFLLAKIKREYKTLPFAYRWLQGE 243
AIEPFAT G G+V E IY + PVRM AR +L +++ YKTLPFA RWL+ +
Sbjct: 185 VAIEPFATNGVGKVGERGECEIYSLLNPRPVRMKMAREILKEVEENYKTLPFAKRWLK-K 243
Query: 244 MPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIVEKDSVIVTTE 295
P+ + + L + G L YPVL E+ GLV+Q+EHT+IVE +TT+
Sbjct: 244 APD----IIISKLAREGVLRAYPVLTEVSGGLVSQWEHTLIVEDGGATITTK 291
>sp|Q58725|AMPM_METJA METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE M)
>gi|2129108|pir||H64465 methionyl aminopeptidase (EC
3.4.11.18) - Methanococcus jannaschii
>gi|1591970|gb|AAB99338.1| (U67573) methionyl
aminopeptidase (map) [Methanococcus jannaschii]
Length = 294
Score = 282 bits (714), Expect = 3e-75
Identities = 145/292 (49%), Positives = 197/292 (66%), Gaps = 4/292 (1%)
Query: 4 DKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFPVNLSLNEIAAHY 63
+K+IEAGKIA KVREEAVKL PGV LLE+AE +E RI ELG +PAFP N+S+NEIAAHY
Sbjct: 7 EKIIEAGKIASKVREEAVKLIXPGVKLLEVAEFVENRIRELGGEPAFPCNISINEIAAHY 66
Query: 64 TPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESAISVAR 123
TP D K+ D +K+D+G H+DGYIADTA+TV + DL++A+ +AL + I
Sbjct: 67 TPKLNDNLEFKDDDVVKLDLGAHVDGYIADTAITVDLSNSYKDLVKASEDALYTVIKEIN 126
Query: 124 AGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYRPHDNYKLREGDV 183
+ I E+G+ I++ I G+ PI NLSGH + RY+LH GISIPN+Y + Y + GD+
Sbjct: 127 PPMNIGEMGKIIQEVIESYGYKPISNLSGHVMHRYELHTGISIPNVYERTNQY-IDVGDL 185
Query: 184 FAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRMVQARFLLAKIKREYKTLPFAYRWLQGE 243
AIEPFAT G G V + IY ++ P+R+ QAR LL I + Y LPFA RW+
Sbjct: 186 VAIEPFATDGFGMVKDGNLGNIYKFLAKRPIRLPQARKLLDVISKNYPYLPFAERWVLKN 245
Query: 244 MPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIVEKDSVIVTTE 295
E +LAL +L ++ +YGYP+L+E NG+V Q EHTI++ ++ V +TT+
Sbjct: 246 ESE---RLALNSLIRASCIYGYPILKERENGIVGQAEHTILITENGVEITTK 294
>sp|P95963|AMPM_SULSO METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE M)
>gi|7435551|pir||S75391 probable methionyl
aminopeptidase (EC 3.4.11.18) - Sulfolobus solfataricus
>gi|1707796|emb|CAA69553.1| (Y08257) eIF-2-associated
67-kD glycoprotein homolog [Sulfolobus solfataricus]
Length = 301
Score = 242 bits (610), Expect = 5e-63
Identities = 129/297 (43%), Positives = 195/297 (65%), Gaps = 5/297 (1%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFPVNLSLNEIAA 61
+++KL+ AGKIA K R+E K +L++ E++E IIE A P+FP N+S+N AA
Sbjct: 5 ELNKLLLAGKIAAKARDEVSLDVKASAKVLDICEEVESIIIENKAFPSFPCNISINSEAA 64
Query: 62 HYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESAISV 121
HY+P DE + EG +K+D+G HIDG+I+DTA+T+ + L++A++ ALE+AI+
Sbjct: 65 HYSPTINDEKRIPEGAVVKLDLGAHIDGFISDTAITISLDSRYQRLLDASKTALEAAITN 124
Query: 122 ARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYRPHDNYKLREG 181
+AG+ I E+GR IE IR +G+ PI NL GH I RY+LHAG+ IPN+Y ++
Sbjct: 125 FKAGLSIGEIGRVIEKVIRAQGYKPIRNLGGHLIRRYELHAGVFIPNVYE-RGLGVIQSD 183
Query: 182 DVFAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRMVQAR--FLLAKIKREYKTLPFAYRW 239
V+AIEPFAT G G+V+E IY +++ ++ + +R L+ I + LPF+ RW
Sbjct: 184 SVYAIEPFATDGGGEVVEGKSITIYS-LKNPNIKGLSSRENELIDFIYTRFNYLPFSERW 242
Query: 240 L-QGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIVEKDSVIVTTE 295
L + +L+ ++ L K GAL GYP+L EI+ G+V+QFEHT+IV+ DS+IV+T+
Sbjct: 243 LKEFSTNVDELRNNIKNLVKKGALRGYPILIEIKKGVVSQFEHTVIVKGDSIIVSTK 299
>gb|AAK40454.1| Methionine aminopeptidase 2 [Sulfolobus solfataricus]
Length = 301
Score = 242 bits (610), Expect = 5e-63
Identities = 129/297 (43%), Positives = 195/297 (65%), Gaps = 5/297 (1%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFPVNLSLNEIAA 61
+++KL+ AGKIA K R+E K +L++ E++E IIE A P+FP N+S+N AA
Sbjct: 5 ELNKLLLAGKIAAKARDEVSLDVKASAKVLDICEEVESIIIENKAFPSFPCNISINSEAA 64
Query: 62 HYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESAISV 121
HY+P DE + EG +K+D+G HIDG+I+DTA+T+ + L++A++ ALE+AI+
Sbjct: 65 HYSPTINDEKRIPEGAVVKLDLGAHIDGFISDTAITISLDSRYQRLLDASKTALEAAITN 124
Query: 122 ARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYRPHDNYKLREG 181
+AG+ I E+GR IE IR +G+ PI NL GH I RY+LHAG+ IPN+Y ++
Sbjct: 125 FKAGLSIGEIGRVIEKVIRAQGYKPIRNLGGHLIRRYELHAGVFIPNVYE-RGLGVIQSD 183
Query: 182 DVFAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRMVQAR--FLLAKIKREYKTLPFAYRW 239
V+AIEPFAT G G+V+E IY +++ ++ + +R L+ I + LPF+ RW
Sbjct: 184 SVYAIEPFATDGGGEVVEGKSITIYS-LKNPNIKGLSSRENELIDFIYTRFNYLPFSERW 242
Query: 240 L-QGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIVEKDSVIVTTE 295
L + +L+ ++ L K GAL GYP+L EI+ G+V+QFEHT+IV+ DS+IV+T+
Sbjct: 243 LKEFSTNVDELRNNIKNLVKKGALRGYPILIEIKKGVVSQFEHTVIVKGDSIIVSTK 299
>emb|CAC12559.1| (AL445067) methionyl aminopeptidase related protein [Thermoplasma
acidophilum]
Length = 293
Score = 237 bits (598), Expect = 1e-61
Identities = 134/294 (45%), Positives = 176/294 (59%), Gaps = 16/294 (5%)
Query: 5 KLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFPVNLSLNEIAAHYT 64
K +EAG+I KK E + +PG LL++A +E + + GA PAFPVNLS+N AAHYT
Sbjct: 11 KYLEAGRIGKKALEIGASMIEPGARLLDVANAMEKFVKDEGALPAFPVNLSINNDAAHYT 70
Query: 65 PYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGME--EDDLMEAAREALESAISVA 122
P D+ T K GD +K+D G HIDGY++DTA+TV VG + DL++AAR+AL +AI +
Sbjct: 71 PAINDKKTFKTGDVVKVDFGAHIDGYMSDTAITVEVGEQGKHSDLIDAARQALNAAIELV 130
Query: 123 RAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYRPHDNYKLREGD 182
R + E+GR I + I GF P+ NL GH +ERY LHA I IPN Y + +L+
Sbjct: 131 RPMKSVNEIGRRIAEVISSYGFKPVRNLGGHGVERYDLHASIFIPN-YDDGNVVRLQPDH 189
Query: 183 VFAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRMVQARFLLAKIKREYKTLPFAYRWLQG 242
AIEPFA+TG G + E P IYM R P I R + LPFA RWL+G
Sbjct: 190 AIAIEPFASTGIGMIHEGQPGNIYMIDRPKPRED-------EIIYRNFNKLPFAERWLEG 242
Query: 243 --EMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIVEKDSVIVTT 294
E P+ +K + + E LY +PVL+E + QFEHT+IV D VIVTT
Sbjct: 243 LVEDPKSYIKRMMASKE----LYSFPVLKEHNGAFIAQFEHTMIVLNDEVIVTT 292
>pir||C72712 probable methionine aminopeptidase APE1114 - Aeropyrum pernix
(strain K1) >gi|5104784|dbj|BAA80099.1| (AP000060) 281aa
long hypothetical methionine aminopeptidase [Aeropyrum
pernix]
Length = 281
Score = 226 bits (570), Expect = 3e-58
Identities = 120/272 (44%), Positives = 168/272 (61%), Gaps = 3/272 (1%)
Query: 27 GVSLLELAEKIEGRIIELGAKPAFPVNLSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVH 86
G S + E +E +I LGA PAFP N+SL+ +AAHYTP D+ ++ G +K+D+G
Sbjct: 4 GASCRRVCELVEEKIRSLGAVPAFPCNISLDSVAAHYTPGLRDDCSIGGGSVVKLDVGAA 63
Query: 87 IDGYIADTAVTVRVGMEEDDLMEAAREALESAISVARAGVEIKELGRAIEDEIRKRGFNP 146
++GYIADTAVTV +G L+EA+ E L +A+ V + G ++GRA+E +R+RGF
Sbjct: 64 VEGYIADTAVTVDLGGGHRSLVEASVEGLRAAMKVLKPGARFYDIGRAVEQAVRRRGFKV 123
Query: 147 IVNLSGHKIERYKLHAGISIPNI-YRPHDNYKLREGDVFAIEPFATTGAGQVIEVPPTLI 205
+ NLSGH I+RY +HAG+SIPN R +++R G FAIEPFAT G G V E I
Sbjct: 124 VKNLSGHTIDRYTIHAGLSIPNYGDRTAWIHRIRPGMTFAIEPFATNGRGMVREGSTVNI 183
Query: 206 YMYVRDAPVRMVQA--RFLLAKIKREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALY 263
Y Y P M+ +L + +Y+TLPF RWL+G + +++ A+R L K GAL+
Sbjct: 184 YAYTGRKPRAMLGGLEERILRHVAEKYRTLPFTPRWLKGMAGDEEVERAVRLLAKLGALH 243
Query: 264 GYPVLREIRNGLVTQFEHTIIVEKDSVIVTTE 295
YPVL E GLV+Q EHT + ++V TE
Sbjct: 244 AYPVLIEAGGGLVSQAEHTFYALRGGIVVVTE 275
>gb|AAG20067.1| (AE005086) methionyl aminopeptidase; Map [Halobacterium sp. NRC-1]
Length = 296
Score = 206 bits (519), Expect = 2e-52
Identities = 126/292 (43%), Positives = 174/292 (59%), Gaps = 10/292 (3%)
Query: 4 DKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFPVNLSLNEIAAHY 63
++ +EAG I V EA G + LE+A E RI ELG +PAFPVN+S+NE A+H
Sbjct: 13 EQYVEAGDILTTVLSEAADRVTVGATHLEVASFAEERIRELGGEPAFPVNISVNEEASHA 72
Query: 64 TPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESAISVAR 123
P D+T E D + +D+GVH+DG+IAD A TV + +L+EAA E+L +AI +
Sbjct: 73 APGADDDTEFGE-DMVCLDVGVHVDGHIADAATTVDLS-GTPELVEAAEESLAAAIDMVE 130
Query: 124 AGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYRPHDN-YKLREGD 182
GV+ LG I+D + G+NP+VNL+GH ++ + H G ++PN R D+ +L GD
Sbjct: 131 PGVQTGALGAEIQDVVEAYGYNPVVNLTGHGMDVFDAHTGPTVPN--RGVDSGAELAVGD 188
Query: 183 VFAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRMVQARFLLAKIKREYKTLPFAYRWLQG 242
V AIEPF TTG G+V E T IY V VR +AR LL ++ ++ LPFA RWL G
Sbjct: 189 VVAIEPFVTTGTGKVTEGAATEIYEVVSSGTVRDRRARQLLDDLE-QFDGLPFAARWLDG 247
Query: 243 EMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIVEKDSVIVTT 294
E ++L LE++ + YPVL+E LV Q EHT+IV +D V T
Sbjct: 248 ARAE----MSLTRLERADIVRSYPVLKEADGELVGQDEHTLIVTEDGCEVVT 295
>pir||T39431 probable methionine metallopeptidase - fission yeast
(Schizosaccharomyces pombe) >gi|3006161|emb|CAA18421.1|
(AL022305) putative methionine metallopeptidase
[Schizosaccharomyces pombe]
Length = 426
Score = 178 bits (448), Expect = 5e-44
Identities = 111/298 (37%), Positives = 163/298 (54%), Gaps = 20/298 (6%)
Query: 6 LIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGR----IIELGAKPA--FPVNLSLNEI 59
L A ++ ++ R+ A + KPG+S++++ IE + E G K FP +SLN
Sbjct: 117 LRRAAEVHRQARQYAQSVIKPGMSMMDVVNTIENTTRALVEEDGLKSGIGFPTGVSLNHC 176
Query: 60 AAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESAI 119
AAHYTP GD T LKE D +K+DIGVH++G I D+A T+ + D+L+ A + A I
Sbjct: 177 AAHYTPNAGDTTILKEKDVMKVDIGVHVNGRIVDSAFTMSFDPQYDNLLAAVKAATNKGI 236
Query: 120 SVARAGVEIKELGRAIED-----EIRKRG----FNPIVNLSGHKIERYKLHAGISIPNIY 170
A + E+G AI++ E+ G I NL GH ++ Y +H G S+P I
Sbjct: 237 EEAGIDARLNEIGEAIQEVMESYEVEINGKTHQVKSIRNLCGHNLDPYIIHGGKSVP-IV 295
Query: 171 RPHDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMYVRDA---PVRMVQARFLLAKIK 227
+ + K+ EG++FAIE F +TG G V E Y + DA P+R+ +A+ LL I
Sbjct: 296 KGGEEIKMEEGEIFAIETFGSTGRGVVHEDMECSHYAKIPDAGHIPLRLPRAKALLNTIT 355
Query: 228 REYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIV 285
+ + TLPF R+L + E + LAL L +G + YP L +IR QFEHTII+
Sbjct: 356 QNFGTLPFCRRYLD-RIGESKYLLALNNLVSAGIVQDYPPLCDIRGSYTAQFEHTIIL 412
>sp|P22624|AMPM_METFE PROBABLE METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE M)
>gi|80949|pir||PS0039 methionyl aminopeptidase (EC
3.4.11.18) - Methanothermus fervidus (fragment)
>gi|551896|gb|AAA72775.1| (M26978) ORF4 [Methanothermus
fervidus]
Length = 188
Score = 176 bits (441), Expect = 3e-43
Identities = 93/189 (49%), Positives = 129/189 (68%), Gaps = 14/189 (7%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFPVNLSLNEIAAH 62
++K +AGKIA KVR++A+K K + +L+LAE IE I ++GAKPAFP N+S+NEI AH
Sbjct: 1 MEKFKKAGKIASKVRKKAIKAVKGEMKILDLAEFIENEIEKMGAKPAFPCNISVNEITAH 60
Query: 63 YTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEED-------------DLME 109
Y+P D+ + GD +KIDIGVH+DG+I DTA TV V ED ++E
Sbjct: 61 YSPPCNDDRKILPGDLVKIDIGVHVDGFIGDTATTVLVEGYEDLKNYNDELAEKNKKMIE 120
Query: 110 AAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNI 169
AA ALE+AI+ R GVEI ++G IE+ I K GF PI NL+GH I+R+ LH+G+SIPN+
Sbjct: 121 AAESALENAINTIRDGVEIGKIGEVIENTINKFGFKPISNLTGHTIDRWVLHSGLSIPNV 180
Query: 170 YRPHDNYKL 178
+ +++KL
Sbjct: 181 -KGQNSHKL 188
>gb|AAG33978.1|AF250964_1 (AF250964) methionine aminopeptidase-like protein [Arabidopsis
thaliana]
Length = 440
Score = 175 bits (438), Expect = 8e-43
Identities = 106/300 (35%), Positives = 171/300 (56%), Gaps = 20/300 (6%)
Query: 4 DKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIEL------GAKPAFPVNLSLN 57
+ L +A ++ ++VR+ + KPG+ +++L E +E + +L A AFP SLN
Sbjct: 129 NSLRQAAEVHRQVRKYMRSILKPGMLMIDLCETLENTVRKLISENGLQAGIAFPTGCSLN 188
Query: 58 EIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALES 117
+AAH+TP GD+T L+ D +K+D G HIDG+I D+A TV D L+ A+R+A +
Sbjct: 189 NVAAHWTPNSGDKTVLQYDDVMKLDFGTHIDGHIVDSAFTVAFNPMFDPLLAASRDATYT 248
Query: 118 AISVARAGVEIKELGRAIED-----EIRKRG----FNPIVNLSGHKIERYKLHAGISIPN 168
I A V + ++G A+++ E+ G I NL+GH I RY++HA S+PN
Sbjct: 249 GIKEAGVDVRLCDVGAAVQEVMESYEVEINGKVYQVKSIRNLNGHSIGRYQIHAEKSVPN 308
Query: 169 IYRPHDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMY---VRDAPVRMVQARFLLAK 225
+ R + K+ EG+++AIE F +TG G V E YM V P+R+ +A+ LLA
Sbjct: 309 V-RGGEQTKMEEGELYAIETFGSTGKGYVREDLECSHYMKNYDVGHVPLRLPRAKQLLAT 367
Query: 226 IKREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIV 285
I + + TL F R+L + E + +AL+ L SG + P + +++ ++QFEHTI++
Sbjct: 368 INKNFSTLAFCRRYLD-RLGETKYLMALKNLCDSGIIEPCPPVCDVKGSYISQFEHTILL 426
>pir||T00698 methionyl aminopeptidase (EC 3.4.11.18) F6E13.31 - Arabidopsis
thaliana >gi|3212871|gb|AAC23422.1| (AC004005) putative
methionine aminopeptidase [Arabidopsis thaliana]
Length = 431
Score = 175 bits (438), Expect = 8e-43
Identities = 106/300 (35%), Positives = 171/300 (56%), Gaps = 20/300 (6%)
Query: 4 DKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIEL------GAKPAFPVNLSLN 57
+ L +A ++ ++VR+ + KPG+ +++L E +E + +L A AFP SLN
Sbjct: 120 NSLRQAAEVHRQVRKYMRSILKPGMLMIDLCETLENTVRKLISENGLQAGIAFPTGCSLN 179
Query: 58 EIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALES 117
+AAH+TP GD+T L+ D +K+D G HIDG+I D+A TV D L+ A+R+A +
Sbjct: 180 NVAAHWTPNSGDKTVLQYDDVMKLDFGTHIDGHIVDSAFTVAFNPMFDPLLAASRDATYT 239
Query: 118 AISVARAGVEIKELGRAIED-----EIRKRG----FNPIVNLSGHKIERYKLHAGISIPN 168
I A V + ++G A+++ E+ G I NL+GH I RY++HA S+PN
Sbjct: 240 GIKEAGVDVRLCDVGAAVQEVMESYEVEINGKVYQVKSIRNLNGHSIGRYQIHAEKSVPN 299
Query: 169 IYRPHDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMY---VRDAPVRMVQARFLLAK 225
+ R + K+ EG+++AIE F +TG G V E YM V P+R+ +A+ LLA
Sbjct: 300 V-RGGEQTKMEEGELYAIETFGSTGKGYVREDLECSHYMKNYDVGHVPLRLPRAKQLLAT 358
Query: 226 IKREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIV 285
I + + TL F R+L + E + +AL+ L SG + P + +++ ++QFEHTI++
Sbjct: 359 INKNFSTLAFCRRYLD-RLGETKYLMALKNLCDSGIIEPCPPVCDVKGSYISQFEHTILL 417
>pir||T47823 hypothetical protein F24G16.260 - Arabidopsis thaliana
>gi|7019693|emb|CAB75818.1| (AL138647) putative protein
[Arabidopsis thaliana]
Length = 435
Score = 174 bits (436), Expect = 1e-42
Identities = 110/295 (37%), Positives = 167/295 (56%), Gaps = 20/295 (6%)
Query: 9 AGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIEL------GAKPAFPVNLSLNEIAAH 62
A ++ ++VR+ + KPG+ + ++ E +E + +L A AFP SLN +AAH
Sbjct: 129 AAEVHRQVRKYVRSIVKPGMLMTDICETLENTVRKLISENGLQAGIAFPTGCSLNWVAAH 188
Query: 63 YTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESAISVA 122
+TP GD+T L+ D +K+D G HIDG+I D A TV D L+ A+REA + I A
Sbjct: 189 WTPNSGDKTVLQYDDVMKLDFGTHIDGHIIDCAFTVAFNPMFDPLLAASREATYTGIKEA 248
Query: 123 RAGVEIKELGRAIED-------EIRKRGF--NPIVNLSGHKIERYKLHAGISIPNIYRPH 173
V + ++G AI++ EI + F I NL+GH I Y++HAG S+P I +
Sbjct: 249 GIDVRLCDIGAAIQEVMESYEVEINGKVFQVKSIRNLNGHSIGPYQIHAGKSVP-IVKGG 307
Query: 174 DNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMYVRDA---PVRMVQARFLLAKIKREY 230
+ K+ EG+ +AIE F +TG G V E YM DA P+R+ +A+ LLA I + +
Sbjct: 308 EQTKMEEGEFYAIETFGSTGKGYVREDLECSHYMKNFDAGHVPLRLPRAKQLLATINKNF 367
Query: 231 KTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIV 285
TL F R+L + E + +AL+ L SG + YP L +++ V+QFEHTI++
Sbjct: 368 STLAFCRRYLD-RIGETKYLMALKNLCDSGIVQPYPPLCDVKGSYVSQFEHTILL 421
>gb|AAG34551.1|AF300880_1 (AF300880) putative methionine aminopeptidase 2 [Arabidopsis
thaliana]
Length = 439
Score = 174 bits (436), Expect = 1e-42
Identities = 110/295 (37%), Positives = 167/295 (56%), Gaps = 20/295 (6%)
Query: 9 AGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIEL------GAKPAFPVNLSLNEIAAH 62
A ++ ++VR+ + KPG+ + ++ E +E + +L A AFP SLN +AAH
Sbjct: 133 AAEVHRQVRKYVRSIVKPGMLMTDICETLENTVRKLISENGLQAGIAFPTGCSLNWVAAH 192
Query: 63 YTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESAISVA 122
+TP GD+T L+ D +K+D G HIDG+I D A TV D L+ A+REA + I A
Sbjct: 193 WTPNSGDKTVLQYDDVMKLDFGTHIDGHIIDCAFTVAFNPMFDPLLAASREATYTGIKEA 252
Query: 123 RAGVEIKELGRAIED-------EIRKRGF--NPIVNLSGHKIERYKLHAGISIPNIYRPH 173
V + ++G AI++ EI + F I NL+GH I Y++HAG S+P I +
Sbjct: 253 GIDVRLCDIGAAIQEVMESYEVEINGKVFQVKSIRNLNGHSIGPYQIHAGKSVP-IVKGG 311
Query: 174 DNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMYVRDA---PVRMVQARFLLAKIKREY 230
+ K+ EG+ +AIE F +TG G V E YM DA P+R+ +A+ LLA I + +
Sbjct: 312 EQTKMEEGEFYAIETFGSTGKGYVREDLECSHYMKNFDAGHVPLRLPRAKQLLATINKNF 371
Query: 231 KTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIV 285
TL F R+L + E + +AL+ L SG + YP L +++ V+QFEHTI++
Sbjct: 372 STLAFCRRYLD-RIGETKYLMALKNLCDSGIVQPYPPLCDVKGSYVSQFEHTILL 425
>gi|5803092 methionine aminopeptidase; eIF-2-associated p67 [Homo sapiens]
>gi|11433896|ref|XP_006612.1| methionine aminopeptidase;
eIF-2-associated p67 [Homo sapiens]
>gi|1703273|sp|P50579|AMP2_HUMAN METHIONINE
AMINOPEPTIDASE 2 (METAP 2) (PEPTIDASE M 2) (INITIATION
FACTOR 2 ASSOCIATED 67 KD GLYCOPROTEIN) (P67)
>gi|2144483|pir||DPHUM2 methionyl aminopeptidase (EC
3.4.11.18) 2 - human >gi|6980777|pdb|1B6A| Human
Methionine Aminopeptidase 2 Complexed With Tnp-470
>gi|687243|gb|AAC63402.1| (U13261) eIF-2-associated p67
homolog [Homo sapiens] >gi|903982|gb|AAA82930.1|
(U29607) methionine aminopeptidase [Homo sapiens]
>gi|1094399|prf||2106146A initiation factor 2-associated
protein [Homo sapiens]
Length = 478
Score = 171 bits (430), Expect = 7e-42
Identities = 108/296 (36%), Positives = 163/296 (54%), Gaps = 20/296 (6%)
Query: 8 EAGKIAKKVREEAVKLAKPGVSLLELAEKIEG---RIIE---LGAKPAFPVNLSLNEIAA 61
EA + ++VR+ + KPG++++E+ EK+E ++I+ L A AFP SLN AA
Sbjct: 171 EAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAA 230
Query: 62 HYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESAISV 121
HYTP GD T L+ D KID G HI G I D A TV + D L++A ++A + I
Sbjct: 231 HYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKC 290
Query: 122 ARAGVEIKELGRAIED-----EIRKRG----FNPIVNLSGHKIERYKLHAGISIPNIYRP 172
A V + ++G AI++ E+ G PI NL+GH I +Y++HAG ++P I +
Sbjct: 291 AGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVP-IVKG 349
Query: 173 HDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMY---VRDAPVRMVQARFLLAKIKRE 229
+ ++ EG+V+AIE F +TG G V + YM V P+R+ + + LL I
Sbjct: 350 GEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINEN 409
Query: 230 YKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIV 285
+ TL F RWL + E + +AL+ L G + YP L +I+ QFEHTI++
Sbjct: 410 FGTLAFCRRWLD-RLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILL 464
>pdb|1BN5| Human Methionine Aminopeptidase 2 >gi|5821858|pdb|1BOA| Human
Methionine Aminopeptidase 2 Complexed With Angiogenesis
Inhibitor Fumagillin
Length = 478
Score = 171 bits (430), Expect = 7e-42
Identities = 108/296 (36%), Positives = 163/296 (54%), Gaps = 20/296 (6%)
Query: 8 EAGKIAKKVREEAVKLAKPGVSLLELAEKIEG---RIIE---LGAKPAFPVNLSLNEIAA 61
EA + ++VR+ + KPG++++E+ EK+E ++I+ L A AFP SLN AA
Sbjct: 171 EAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAA 230
Query: 62 HYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESAISV 121
HYTP GD T L+ D KID G HI G I D A TV + D L++A ++A + I
Sbjct: 231 HYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKC 290
Query: 122 ARAGVEIKELGRAIED-----EIRKRG----FNPIVNLSGHKIERYKLHAGISIPNIYRP 172
A V + ++G AI++ E+ G PI NL+GH I +Y++HAG ++P I +
Sbjct: 291 AGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVP-IIKG 349
Query: 173 HDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMY---VRDAPVRMVQARFLLAKIKRE 229
+ ++ EG+V+AIE F +TG G V + YM V P+R+ + + LL I
Sbjct: 350 GEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINEN 409
Query: 230 YKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIV 285
+ TL F RWL + E + +AL+ L G + YP L +I+ QFEHTI++
Sbjct: 410 FGTLAFCRRWLD-RLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILL 464
>pdb|1B59|A Chain A, Complex Of Human Methionine Aminopeptidase-2 Complexed
With Ovalicin
Length = 370
Score = 171 bits (430), Expect = 7e-42
Identities = 108/296 (36%), Positives = 163/296 (54%), Gaps = 20/296 (6%)
Query: 8 EAGKIAKKVREEAVKLAKPGVSLLELAEKIEG---RIIE---LGAKPAFPVNLSLNEIAA 61
EA + ++VR+ + KPG++++E+ EK+E ++I+ L A AFP SLN AA
Sbjct: 63 EAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAA 122
Query: 62 HYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESAISV 121
HYTP GD T L+ D KID G HI G I D A TV + D L++A ++A + I
Sbjct: 123 HYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKC 182
Query: 122 ARAGVEIKELGRAIED-----EIRKRG----FNPIVNLSGHKIERYKLHAGISIPNIYRP 172
A V + ++G AI++ E+ G PI NL+GH I +Y++HAG ++P I +
Sbjct: 183 AGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVP-IVKG 241
Query: 173 HDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMY---VRDAPVRMVQARFLLAKIKRE 229
+ ++ EG+V+AIE F +TG G V + YM V P+R+ + + LL I
Sbjct: 242 GEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINEN 301
Query: 230 YKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIV 285
+ TL F RWL + E + +AL+ L G + YP L +I+ QFEHTI++
Sbjct: 302 FGTLAFCRRWLD-RLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILL 356
>sp|P38062|AMP2_RAT METHIONINE AMINOPEPTIDASE 2 (METAP 2) (PEPTIDASE M 2) (INITIATION
FACTOR 2 ASSOCIATED 67 KD GLYCOPROTEIN) (P67)
Length = 478
Score = 169 bits (425), Expect = 3e-41
Identities = 108/296 (36%), Positives = 162/296 (54%), Gaps = 20/296 (6%)
Query: 8 EAGKIAKKVREEAVKLAKPGVSLLELAEKIEG---RIIE---LGAKPAFPVNLSLNEIAA 61
EA + ++VR+ + KPG++++E+ EK+E ++I+ L A AFP SLN AA
Sbjct: 171 EAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAA 230
Query: 62 HYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESAISV 121
HYTP GD T L+ D KID G HI G I D A TV + D L++A ++A + I
Sbjct: 231 HYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDILLKAVKDATNTGIKC 290
Query: 122 ARAGVEIKELGRAIED-----EIRKRG----FNPIVNLSGHKIERYKLHAGISIPNIYRP 172
A V + ++G AI++ E+ G PI NL+GH I Y++HAG ++P I +
Sbjct: 291 AGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGPYRIHAGKTVP-IVKG 349
Query: 173 HDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMY---VRDAPVRMVQARFLLAKIKRE 229
+ ++ EG+V+AIE F +TG G V + YM V P+R+ + + LL I
Sbjct: 350 GEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINEN 409
Query: 230 YKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIV 285
+ TL F RWL + E + +AL+ L G + YP L +I+ QFEHTI++
Sbjct: 410 FGTLAFCRRWLD-RLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILL 464
>pir||A46702 methionyl aminopeptidase (EC 3.4.11.18) 2 - rat
>gi|204004|gb|AAA41111.1| (L10652) initiation factor 2
associated 67 kDa protein [Rattus norvegicus]
Length = 480
Score = 169 bits (424), Expect = 3e-41
Identities = 108/295 (36%), Positives = 161/295 (53%), Gaps = 20/295 (6%)
Query: 8 EAGKIAKKVREEAVKLAKPGVSLLELAEKIEG---RIIE---LGAKPAFPVNLSLNEIAA 61
EA + ++VR+ + KPG++++E+ EK+E ++I+ L A AFP SLN AA
Sbjct: 171 EAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAA 230
Query: 62 HYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESAISV 121
HYTP GD T L+ D KID G HI G I D A TV + D L++A ++A + I
Sbjct: 231 HYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDILLKAVKDATNTGIKC 290
Query: 122 ARAGVEIKELGRAIED-----EIRKRG----FNPIVNLSGHKIERYKLHAGISIPNIYRP 172
A V + ++G AI++ E+ G PI NL+GH I Y++HAG ++P I +
Sbjct: 291 AGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGPYRIHAGKTVP-IVKG 349
Query: 173 HDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMY---VRDAPVRMVQARFLLAKIKRE 229
+ ++ EG+V+AIE F +TG G V + YM V P+R+ + + LL I
Sbjct: 350 GEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINEN 409
Query: 230 YKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTII 284
+ TL F RWL + E + +AL+ L G + YP L +I+ QFEHTI+
Sbjct: 410 FGTLAFCRRWLD-RLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTIL 463
>gi|9789873 methionine aminopeptidase 2; initiation factor 2-associated protein
(p67) [Mus musculus] >gi|3023282|sp|O08663|AMP2_MOUSE
METHIONINE AMINOPEPTIDASE 2 (METAP 2) (PEPTIDASE M 2)
(INITIATION FACTOR 2 ASSOCIATED 67 KD GLYCOPROTEIN)
(P67) >gi|2055254|dbj|BAA19789.1| (AB003144) initiation
factor 2-associated 67kDa protein [Mus musculus]
Length = 478
Score = 169 bits (423), Expect = 4e-41
Identities = 108/296 (36%), Positives = 161/296 (53%), Gaps = 20/296 (6%)
Query: 8 EAGKIAKKVREEAVKLAKPGVSLLELAEKIEG---RIIE---LGAKPAFPVNLSLNEIAA 61
EA + ++VR+ + KPG++++E+ EK+E ++I+ L A AFP SLN AA
Sbjct: 171 EAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAA 230
Query: 62 HYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESAISV 121
HYTP GD T L+ D KID G HI G I D A TV + D L+ A ++A + I
Sbjct: 231 HYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDILLTAVKDATNTGIKC 290
Query: 122 ARAGVEIKELGRAIED-----EIRKRG----FNPIVNLSGHKIERYKLHAGISIPNIYRP 172
A V + ++G AI++ E+ G PI NL+GH I Y++HAG ++P I +
Sbjct: 291 AGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGPYRIHAGKTVP-IVKG 349
Query: 173 HDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMY---VRDAPVRMVQARFLLAKIKRE 229
+ ++ EG+V+AIE F +TG G V + YM V P+R+ + + LL I
Sbjct: 350 GEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINEN 409
Query: 230 YKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIV 285
+ TL F RWL + E + +AL+ L G + YP L +I+ QFEHTI++
Sbjct: 410 FGTLAFCRRWLD-RLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILL 464
>emb|CAB55167.1| (AL117205) contains similarity to Pfam domain: PF00557
(metallopeptidase family M24), Score=239.2,
E-value=1.9e-68, N=1~cDNA EST EMBL:Z14814 comes from
this gene~cDNA EST EMBL:Z14913 comes from this gene~cDNA
EST EMBL:M89428 comes from this gene~cDNA E>
Length = 444
Score = 164 bits (410), Expect = 1e-39
Identities = 102/292 (34%), Positives = 162/292 (54%), Gaps = 22/292 (7%)
Query: 14 KKVREEAVKLAKPGVSLLELAEKIEG---RIIE---LGAKPAFPVNLSLNEIAAHYTPYK 67
++VR+ KPG++++E+ E++E R+I+ L A AFP SLN AAHYTP
Sbjct: 141 RQVRKYVKSWIKPGMTMIEICERLETTSRRLIKEQGLEAGLAFPTGCSLNHCAAHYTPNA 200
Query: 68 GDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESAISVARAGVE 127
GD T L+ GD KID G+H+ G + D+A TV + D L+EA REA + I + V
Sbjct: 201 GDTTVLQYGDVCKIDYGIHVRGRLIDSAFTVHFDPKFDPLVEAVREATNAGIKESGIDVR 260
Query: 128 IKELGRAIED-----EIRKRG----FNPIVNLSGHKIERYKLHAGISIPNIYRPHDNYKL 178
+ ++G +E+ E+ G PI NL+GH I +Y++HAG ++P I + + K+
Sbjct: 261 LCDVGEIVEEVMTSHEVELDGKSYVVKPIRNLNGHSIAQYRIHAGKTVP-IVKGGEQTKM 319
Query: 179 REGDVFAIEPFATTGAGQVIEVPPTLIYM-----YVRDAPVRMVQARFLLAKIKREYKTL 233
E +++AIE F +TG G V + T YM P+R+ +++ LL I + + TL
Sbjct: 320 EENEIYAIETFGSTGKGYVHDDMETSHYMKNFELADEKIPLRLQKSKGLLNLIDKNFATL 379
Query: 234 PFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIV 285
F RW+ + E + +AL+ L G + YP L +++ Q+EHTI++
Sbjct: 380 AFCRRWID-RLGETKYLMALKDLCDKGIVDPYPPLCDVKGCYTAQWEHTILM 430
>gb|AAC05144.1| (AF049912) methionine aminopeptidase [Drosophila melanogaster]
Length = 448
Score = 155 bits (389), Expect = 4e-37
Identities = 102/299 (34%), Positives = 160/299 (53%), Gaps = 20/299 (6%)
Query: 5 KLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEG---RIIE---LGAKPAFPVNLSLNE 58
+L +A + ++ R+ + KPG++++++ E++E R+I L A AFP SLN
Sbjct: 138 ELRQAAEAHRQTRQYMQRYIKPGMTMIQICEELENTARRLIGENGLEAGLAFPTGCSLNH 197
Query: 59 IAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESA 118
AAHYTP GD T L+ D KID G HI G I D A T+ + D L++A +EA +
Sbjct: 198 CAAHYTPNAGDPTVLQYDDVCKIDFGTHIKGRIIDCAFTLTFNNKYDKLLQAVKEATNTG 257
Query: 119 ISVARAGVEIKELGRAIED-----EIRKRG----FNPIVNLSGHKIERYKLHAGISIPNI 169
I A V + ++G AI++ EI G I NL+GH I Y++HAG ++P I
Sbjct: 258 IREAGIDVRLCDIGAAIQEVMESYEIELDGKTYPIKAIRNLNGHSISPYRIHAGKTVP-I 316
Query: 170 YRPHDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMYVRD---APVRMVQARFLLAKI 226
+ ++ ++ E + +AIE F +TG G V + YM D P+R+ ++ LL I
Sbjct: 317 VKGGESTRMEEDEFYAIETFGSTGRGLVHDDMDCSHYMKNFDLPFVPLRLQSSKQLLGTI 376
Query: 227 KREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIV 285
+ + TL F RWL + ++AL+ L G + YP L +I+ Q+EHTI++
Sbjct: 377 NKNFGTLAFCKRWLD-RAGATKYQMALKDLCDKGIVEAYPPLCDIKGCYTAQYEHTIML 434
>gb|AAF52807.1| (AE003626) und gene product [Drosophila melanogaster]
Length = 448
Score = 155 bits (389), Expect = 4e-37
Identities = 102/299 (34%), Positives = 160/299 (53%), Gaps = 20/299 (6%)
Query: 5 KLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEG---RIIE---LGAKPAFPVNLSLNE 58
+L +A + ++ R+ + KPG++++++ E++E R+I L A AFP SLN
Sbjct: 138 ELRQAAEAHRQTRQYMQRYIKPGMTMIQICEELENTARRLIGENGLEAGLAFPTGCSLNH 197
Query: 59 IAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREALESA 118
AAHYTP GD T L+ D KID G HI G I D A T+ + D L++A +EA +
Sbjct: 198 CAAHYTPNAGDPTVLQYDDVCKIDFGTHIKGRIIDCAFTLTFNNKYDKLLQAVKEATNTG 257
Query: 119 ISVARAGVEIKELGRAIED-----EIRKRG----FNPIVNLSGHKIERYKLHAGISIPNI 169
I A V + ++G AI++ EI G I NL+GH I Y++HAG ++P I
Sbjct: 258 IREAGIDVRLCDIGAAIQEVMESYEIELDGKTYPIKAIRNLNGHSISPYRIHAGKTVP-I 316
Query: 170 YRPHDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMYVRD---APVRMVQARFLLAKI 226
+ ++ ++ E + +AIE F +TG G V + YM D P+R+ ++ LL I
Sbjct: 317 VKGGESTRMEEDEFYAIETFGSTGRGLVHDDMDCSHYMKNFDLPFVPLRLQSSKQLLGTI 376
Query: 227 KREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIV 285
+ + TL F RWL + ++AL+ L G + YP L +I+ Q+EHTI++
Sbjct: 377 NKNFGTLAFCKRWLD-RAGATKYQMALKDLCDKGIVEAYPPLCDIKGCYTAQYEHTIML 434
>pir||S45411 methionyl aminopeptidase (EC 3.4.11.18) MAP2 - yeast
(Saccharomyces cerevisiae) >gi|496684|emb|CAA56011.1|
(X79489) D-349 protein [Saccharomyces cerevisiae]
Length = 349
Score = 152 bits (380), Expect = 5e-36
Identities = 104/305 (34%), Positives = 153/305 (50%), Gaps = 31/305 (10%)
Query: 8 EAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIEL-GAKP------------AFPVNL 54
+ +I ++VR PG+ L+++A+ IE + GA+ FP L
Sbjct: 35 KGAEIHRRVRRAIKDRIVPGMKLMDIADMIENTTRKYTGAENLLAMEDPKSQGIGFPTGL 94
Query: 55 SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREA 114
SLN AAH+TP GD+T LK D +K+D GV ++G I D+A TV + D+L+ A ++A
Sbjct: 95 SLNHCAAHFTPNAGDKTVLKYEDVMKVDYGVQVNGNIIDSAFTVSFDPQYDNLLAAVKDA 154
Query: 115 LESAISVARAGVEIKELGRAIED-----EIRKRG----FNPIVNLSGHKIERYKLHAGIS 165
+ I A V + ++G AI++ E+ G P NL GH I Y++H G S
Sbjct: 155 TYTGIKEAGIDVRLTDIGEAIQEVMESYEVEINGETYQVKPCRNLCGHSIAPYRIHGGKS 214
Query: 166 IPNIYRPHDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRMV-----QAR 220
+P I + D K+ EG+ FAIE F +TG G V + Y R A V A+
Sbjct: 215 VP-IVKNGDTTKMEEGEHFAIETFGSTGRGYV--TAGGEVSHYARSAEDHQVMPTLDSAK 271
Query: 221 FLLAKIKREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFE 280
LL I R + TLPF R+L + + + AL L + G + YP L +I QFE
Sbjct: 272 NLLKTIDRNFGTLPFCRRYLD-RLGQEKYLFALNNLVRHGLVQDYPPLNDIPGSYTAQFE 330
Query: 281 HTIIV 285
HTI++
Sbjct: 331 HTILL 335
>sp|P38174|AMP2_YEAST METHIONINE AMINOPEPTIDASE 2 (METAP 2) (PEPTIDASE M 2)
>gi|1045302|gb|AAC49142.1| (U17437) methionine
aminopeptidase 2 [Saccharomyces cerevisiae]
Length = 421
Score = 152 bits (380), Expect = 5e-36
Identities = 104/305 (34%), Positives = 153/305 (50%), Gaps = 31/305 (10%)
Query: 8 EAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIEL-GAKP------------AFPVNL 54
+ +I ++VR PG+ L+++A+ IE + GA+ FP L
Sbjct: 107 KGAEIHRRVRRAIKDRIVPGMKLMDIADMIENTTRKYTGAENLLAMEDPKSQGIGFPTGL 166
Query: 55 SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREA 114
SLN AAH+TP GD+T LK D +K+D GV ++G I D+A TV + D+L+ A ++A
Sbjct: 167 SLNHCAAHFTPNAGDKTVLKYEDVMKVDYGVQVNGNIIDSAFTVSFDPQYDNLLAAVKDA 226
Query: 115 LESAISVARAGVEIKELGRAIED-----EIRKRG----FNPIVNLSGHKIERYKLHAGIS 165
+ I A V + ++G AI++ E+ G P NL GH I Y++H G S
Sbjct: 227 TYTGIKEAGIDVRLTDIGEAIQEVMESYEVEINGETYQVKPCRNLCGHSIAPYRIHGGKS 286
Query: 166 IPNIYRPHDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRMV-----QAR 220
+P I + D K+ EG+ FAIE F +TG G V + Y R A V A+
Sbjct: 287 VP-IVKNGDTTKMEEGEHFAIETFGSTGRGYV--TAGGEVSHYARSAEDHQVMPTLDSAK 343
Query: 221 FLLAKIKREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFE 280
LL I R + TLPF R+L + + + AL L + G + YP L +I QFE
Sbjct: 344 NLLKTIDRNFGTLPFCRRYLD-RLGQEKYLFALNNLVRHGLVQDYPPLNDIPGSYTAQFE 402
Query: 281 HTIIV 285
HTI++
Sbjct: 403 HTILL 407
>gi|6319380 methionine aminopeptidase 2; Map2p [Saccharomyces cerevisiae]
>gi|1870087|emb|CAA84913.1| (Z35852) ORF YBL091c
[Saccharomyces cerevisiae]
Length = 421
Score = 152 bits (380), Expect = 5e-36
Identities = 104/305 (34%), Positives = 153/305 (50%), Gaps = 31/305 (10%)
Query: 8 EAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIEL-GAKP------------AFPVNL 54
+ +I ++VR PG+ L+++A+ IE + GA+ FP L
Sbjct: 107 KGAEIHRRVRRAIKDRIVPGMKLMDIADMIENTTRKYTGAENLLAMEDPKSQGIGFPTGL 166
Query: 55 SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEAAREA 114
SLN AAH+TP GD+T LK D +K+D GV ++G I D+A TV + D+L+ A ++A
Sbjct: 167 SLNHCAAHFTPNAGDKTVLKYEDVMKVDYGVQVNGNIIDSAFTVSFDPQYDNLLAAVKDA 226
Query: 115 LESAISVARAGVEIKELGRAIED-----EIRKRG----FNPIVNLSGHKIERYKLHAGIS 165
+ I A V + ++G AI++ E+ G P NL GH I Y++H G S
Sbjct: 227 TYTGIKEAGIDVRLTDIGEAIQEVMESYEVEINGETYQVKPCRNLCGHSIAPYRIHGGKS 286
Query: 166 IPNIYRPHDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRMV-----QAR 220
+P I + D K+ EG+ FAIE F +TG G V + Y R A V A+
Sbjct: 287 VP-IVKNGDTTKMEEGEHFAIETFGSTGRGYV--TAGGEVSHYARSAEDHQVMPTLDSAK 343
Query: 221 FLLAKIKREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQFE 280
LL I R + TLPF R+L + + + AL L + G + YP L +I QFE
Sbjct: 344 NLLKTIDRNFGTLPFCRRYLD-RLGQEKYLFALNNLVRHGLVQDYPPLNDIPGSYTAQFE 402
Query: 281 HTIIV 285
HTI++
Sbjct: 403 HTILL 407
>sp|P56102|AMPM_HELPY METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE M)
>gi|7435550|pir||C64682 methionine amino peptidase -
Helicobacter pylori (strain 26695)
>gi|2314463|gb|AAD08340.1| (AE000633) methionine amino
peptidase (map) [Helicobacter pylori 26695]
Length = 253
Score = 113 bits (279), Expect = 3e-24
Identities = 71/210 (33%), Positives = 113/210 (53%), Gaps = 19/210 (9%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFP--------VN 53
++ L +AG++ + + +PGVSLLEL + E I A+PAF V
Sbjct: 10 EIKALRKAGELTAQALALLEREVRPGVSLLELDKMAEDFIKSSHARPAFKGLYGFPNSVC 69
Query: 54 LSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGM---EEDDLMEA 110
+SLNE+ H P + L+EGD + +D+GV +DGY D+A+T+ +G +++ L+
Sbjct: 70 MSLNEVVIHGIP---TDYVLQEGDIIGLDLGVEVDGYYGDSALTLPIGAISPQDEKLLAC 126
Query: 111 AREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNI- 169
++E+L AI+ R G+ KEL + +E I +RGF P+ GH I + K H IPN
Sbjct: 127 SKESLMHAINSIRVGMHFKELSQILESTITERGFVPLKGFCGHGIGK-KPHEEPEIPNYL 185
Query: 170 ---YRPHDNYKLREGDVFAIEPFATTGAGQ 196
+P+ K++EG VF +EP G+
Sbjct: 186 EKGVKPNSGPKIKEGMVFCLEPMVCQKQGE 215
>sp|Q9ZJT0|AMPM_HELPJ METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE M)
>gi|7435549|pir||C71833 methionine aminopeptidase -
Helicobacter pylori (strain J99)
>gi|4155829|gb|AAD06803.1| (AE001547) METHIONINE
AMINOPEPTIDASE [Helicobacter pylori J99]
Length = 253
Score = 110 bits (273), Expect = 2e-23
Identities = 71/210 (33%), Positives = 112/210 (52%), Gaps = 19/210 (9%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFP--------VN 53
++ L +AG++ + + +PGVSLLEL + E I A+PAF V
Sbjct: 10 EIKALRKAGELTAQALALLEREVRPGVSLLELDKMAEDFIKSSHARPAFKGLYGFPNSVC 69
Query: 54 LSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGM---EEDDLMEA 110
+SLNE+ H P + L+EGD + +D+GV +DGY D+A+T+ +G +++ L+
Sbjct: 70 MSLNEVVIHGIP---TDYVLQEGDIIGLDLGVEVDGYYGDSALTLPIGAISPQDEKLLAC 126
Query: 111 AREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNI- 169
++E+L AIS R G+ KEL + +E I +RGF P+ GH I + K H IPN
Sbjct: 127 SKESLMHAISSIRVGMHFKELSQILEGAITERGFVPLKGFCGHGIGK-KPHEEPEIPNYL 185
Query: 170 ---YRPHDNYKLREGDVFAIEPFATTGAGQ 196
+ + K++EG VF +EP G+
Sbjct: 186 EKGVKANSGPKIKEGMVFCLEPMVCQKQGE 215
>pir||T51151 probable nuclear DNA-binding protein G2p [imported] - Arabidopsis
thaliana >gi|1657617|gb|AAB18127.1| (U72503) G2p
[Arabidopsis thaliana] >gi|3068707|gb|AAC14407.1|
(AF049236) putative nuclear DNA-binding protein G2p
[Arabidopsis thaliana]
Length = 392
Score = 109 bits (269), Expect = 5e-23
Identities = 80/307 (26%), Positives = 145/307 (47%), Gaps = 28/307 (9%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKP------------AF 50
V K A +I K + + KP ++++ EK + I E A AF
Sbjct: 20 VTKYKSAAEIVNKALQVVLAECKPKAKIVDICEKGDSFIKEQTASMYKNSKKKIERGVAF 79
Query: 51 PVNLSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVT-----VRVGMEED 105
P +S+N H++P DE+ L++GD +KID+G HIDG+IA T + +
Sbjct: 80 PTCISVNNTVGHFSPLASDESVLEDGDMVKIDMGCHIDGFIALVGHTHVLQEGPLSGRKA 139
Query: 106 DLMEAAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGIS 165
D++ AA A + A+ + R G + ++ AI+ + + H+++++ +
Sbjct: 140 DVIAAANTAADVALRLVRPGKKNTDVTEAIQKVAAAYDCKIVEGVLSHQLKQHVIDGNKV 199
Query: 166 IPNIYRPH---DNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAPV----RMVQ 218
+ ++ P D + E +V+AI+ A+TG G+ + +Y +D V +M
Sbjct: 200 VLSVSSPETTVDEVEFEENEVYAIDIVASTGDGKPKLLDEKQTTIYKKDESVNYQLKMKA 259
Query: 219 ARFLLAKIKREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLVTQ 278
+RF++++IK+ + +PF R L+ E + +L L G L YPVL E V Q
Sbjct: 260 SRFIISEIKQNFPRMPFTARSLE----EKRARLGLVECVNHGHLQPYPVLYEKPGDFVAQ 315
Query: 279 FEHTIIV 285
+ T+++
Sbjct: 316 IKFTVLL 322
>pir||T02069 probable DNA-binding protein GBP16 - rice
>gi|2511541|gb|AAB80919.1| (AF020787) DNA-binding
protein GBP16 [Oryza sativa]
Length = 393
Score = 108 bits (268), Expect = 7e-23
Identities = 86/313 (27%), Positives = 146/313 (46%), Gaps = 40/313 (12%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRI--------------IELGAKP 48
V K +A I + V L KP ++++ EK + I IE G
Sbjct: 21 VTKYKDAADIINNALKLVVSLCKPKAKIVDICEKGDSYIREQTGNIYKNVKRKIERGV-- 78
Query: 49 AFPVNLSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIA---------DTAVTVR 99
AFP +S+N H++P DE L+E D +KID+G HIDG+IA D AVT +
Sbjct: 79 AFPTCVSVNNTVCHFSPLATDEAVLEENDMVKIDMGCHIDGFIAVVAHTHVIHDGAVTGK 138
Query: 100 VGMEEDDLMEAAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYK 159
D++ AA A E A+ R G + K++ AI+ + + H+++++
Sbjct: 139 AA----DVLAAANTAAEVALRFVRPGKKNKDVTEAIQKVAAAYDSVSVEGVLSHQLKQFV 194
Query: 160 LHAG---ISIPNIYRPHDNYKLREGDVFAIEPFATTGAG--QVIEVPPTLIYMYVRDA-- 212
+ +S+ N D+ + E +V+AI+ +TG G ++++ T IY D
Sbjct: 195 IDGNKVVLSVSNADTKVDDAEFEENEVYAIDIVTSTGEGKPKLLDEKQTTIYKRAVDKNY 254
Query: 213 PVRMVQARFLLAKIKREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIR 272
++M +RF+ ++I +++ +PF R L+ E + +L L L YPVL E
Sbjct: 255 HLKMKASRFIFSEISQKFPIMPFTARALE----EKRARLGLVECMNHELLQPYPVLHEKP 310
Query: 273 NGLVTQFEHTIIV 285
LV + T+++
Sbjct: 311 GDLVAHIKFTVLL 323
>gi|6755100 proliferation-associated protein 1 [Mus musculus]
>gi|1709587|sp|P50580|PLS1_MOUSE
PROLIFERATION-ASSOCIATED PROTEIN 1 (PROTEIN P38-2G4)
>gi|1167967|gb|AAB60513.1| (U43918)
proliferation-associated protein 1 [Mus musculus]
Length = 394
Score = 108 bits (266), Expect = 1e-22
Identities = 79/312 (25%), Positives = 148/312 (47%), Gaps = 33/312 (10%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKP-----------AFP 51
V K G IA +V V+ + GVS+L L EK + I+E K AFP
Sbjct: 18 VTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFP 77
Query: 52 VNLSLNEIAAHYTPYKGDET-TLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEED----- 105
++S+N H++P K D+ LKEGD +KID+GVH+DG+IA+ A T +G+ +
Sbjct: 78 TSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVIGVAQGTQVTG 137
Query: 106 ---DLMEAAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHA 162
D+++AA E+A+ + + G + ++ A PI + H+++++ +
Sbjct: 138 RKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVIDG 197
Query: 163 GISI-----PNIYRPHDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAP---- 213
+I + H+ + +V+A++ ++G G+ + +Y RD
Sbjct: 198 EKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTT-IYKRDPSKQYG 256
Query: 214 VRMVQARFLLAKIKREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRN 273
++M +R ++++R + +PF R + E + ++ + K L + VL E
Sbjct: 257 LKMKTSRAFFSEVERRFDAMPFTLRAFEDEK---KARMGVVECAKHELLQPFNVLYEKEG 313
Query: 274 GLVTQFEHTIIV 285
V QF+ T+++
Sbjct: 314 EFVAQFKFTVLL 325
>gb|AAF50751.1| (AE003565) CG10576 gene product [Drosophila melanogaster]
Length = 391
Score = 107 bits (264), Expect = 2e-22
Identities = 90/324 (27%), Positives = 154/324 (46%), Gaps = 40/324 (12%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKP-----------AFP 51
V K AG+I K + + L S+ E+ + + ++ E K AFP
Sbjct: 18 VTKYKLAGEIVNKTLKAVIGLCVVDASVREICTQGDNQLTEETGKVYKKEKDLKKGIAFP 77
Query: 52 VNLSLNEIAAHYTPYKGD-ETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEED----- 105
LS+N H++P K D + TLK GD +KID+G HIDG+IA A T+ VG D
Sbjct: 78 TCLSVNNCVCHFSPAKNDADYTLKAGDVVKIDLGAHIDGFIAVAAHTIVVGAAADQKISG 137
Query: 106 ---DLMEAAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHA 162
D++ AA A+++A+ + ++G L A++ PI + H+++++K+
Sbjct: 138 RQADVILAAYWAVQAALRLLKSGANNYSLTDAVQQISESYKCKPIEGMLSHELKQFKIDG 197
Query: 163 GISIPNIYRP-------HDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAP-- 213
+I I P H+ +V+AI+ +TG G V T + +Y +
Sbjct: 198 EKTI--IQNPSEAQRKEHEKCTFETYEVYAIDVIVSTGEG-VGREKDTKVSIYKKSEENY 254
Query: 214 -VRMVQARFLLAKIKREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSG--ALYGYPVLRE 270
++M +R LLA++K +Y +PF R E + K + +E G + + VL E
Sbjct: 255 MLKMKASRALLAEVKTKYGNMPFNIRSF-----EEETKARMGVVECVGHKMIEPFQVLYE 309
Query: 271 IRNGLVTQFEHTIIVEKDSVIVTT 294
+ +V QF+HT+++ + V + T
Sbjct: 310 KPSEIVAQFKHTVLLMPNGVNLVT 333
>sp|O66489|AMPM_AQUAE METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE M)
>gi|7435557|pir||F70307 methionyl aminopeptidase -
Aquifex aeolicus >gi|2982825|gb|AAC06448.1| (AE000672)
methionyl aminopeptidase [Aquifex aeolicus]
Length = 258
Score = 106 bits (261), Expect = 4e-22
Identities = 72/217 (33%), Positives = 109/217 (50%), Gaps = 22/217 (10%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAF----------- 50
+++K+ +A +I +V + KPGVS +L + GAKPAF
Sbjct: 10 EIEKIRKASQIVAEVLHIVAENVKPGVSTWDLEMIARKETEKRGAKPAFLGYKPPFSDVR 69
Query: 51 ---PVNLSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGM---EE 104
+ +S+N+ H P K E +KEGD + ID G DGY D+A+TV G E
Sbjct: 70 YPAALCISINDEVVHGLPKK--EKVIKEGDVVSIDFGAIYDGYAGDSAITVIAGKGSPEA 127
Query: 105 DDLMEAAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGI 164
L+EA +EAL +AI A G ++ ++ +AI + K GF I+ GH + R K+H
Sbjct: 128 QKLLEATKEALYNAIEKALPGKKVGDITKAIHETAEKYGFKTILRYGGHGVGR-KVHQEP 186
Query: 165 SIPNIYRP--HDNYKLREGDVFAIEPFATTGAGQVIE 199
+PN + N +LR+G V AIEP + G + +E
Sbjct: 187 FVPNNVKDIGKKNPRLRQGMVIAIEPMLSIGTEETVE 223
>gb|AAB03665.1| (U61403) PrlA [Dictyostelium discoideum]
Length = 379
Score = 105 bits (260), Expect = 6e-22
Identities = 90/309 (29%), Positives = 140/309 (45%), Gaps = 31/309 (10%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKP-----------AFP 51
VD AG IA + + G ++++ + + I AK AFP
Sbjct: 19 VDSYNAAGIIANNAIKHVISKCVVGALVVDICQYGDDFIEAEAAKTFTKRKNLEKGIAFP 78
Query: 52 VNLSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLME-- 109
+S+N H++P KG+ TLK+GD +KID+G HIDGYIA A T+ +G + M
Sbjct: 79 TCVSVNNCVGHFSPLKGNTRTLKQGDVVKIDLGCHIDGYIAVGAHTIIIGNTSAESMTGK 138
Query: 110 ------AAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAG 163
AA ALE+A+ + R G E+ + IE G + + H+++R+ +
Sbjct: 139 VADAICAAHYALEAALRMIRPGKTSNEVTQVIEKISDMYGVTSVSGILSHELKRFIIDGE 198
Query: 164 ISIPNIYRPH---DNYKLREGDVFAIEPFATTGAGQVIEVP--PTLIYMYVRDAPVRMVQ 218
I + P Y+ +E +V+ I+ +TG G+ E PT IY D+ ++
Sbjct: 199 KVIFSKNEPSQKIQTYEFQENEVYCIDIVMSTGEGKAREEADRPT-IYRRNLDSTYKLKS 257
Query: 219 --ARFLLAKIKREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNGLV 276
+R +I + Y LPF R E KL L L + L YPVL + V
Sbjct: 258 KASRDFKDQIVKRYSALPFPLR----NFDEKVSKLGLVELVEHQVLAAYPVLFDRSGCEV 313
Query: 277 TQFEHTIIV 285
QF+ T++V
Sbjct: 314 VQFKTTVLV 322
>gi|5453842 proliferation-associated 2G4, 38kD [Homo sapiens]
>gi|2697005|gb|AAB91536.1| (U59435) cell cycle protein
p38-2G4 homolog [Homo sapiens]
Length = 394
Score = 105 bits (260), Expect = 6e-22
Identities = 79/312 (25%), Positives = 147/312 (46%), Gaps = 33/312 (10%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKP-----------AFP 51
V K G IA +V V+ + GVS+L L EK + I+E K AFP
Sbjct: 18 VTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFP 77
Query: 52 VNLSLNEIAAHYTPYKGDET-TLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEED----- 105
++S+N H++P K D+ LKEGD +KID+GVH+DG+IA+ A T V + +
Sbjct: 78 TSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTG 137
Query: 106 ---DLMEAAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHA 162
D+++AA E+A+ + + G + ++ A PI + H+++++ +
Sbjct: 138 RKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVIDG 197
Query: 163 GISI-----PNIYRPHDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAP---- 213
+I + H+ + +V+A++ ++G G+ + +Y RD
Sbjct: 198 EKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTT-IYKRDPSKQYG 256
Query: 214 VRMVQARFLLAKIKREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRN 273
++M +R ++++R + +PF R + E + ++ + K L + VL E
Sbjct: 257 LKMKTSRAFFSEVERRFDAMPFTLRAFEDEK---KARMGVVECAKHELLQPFNVLYEKEG 313
Query: 274 GLVTQFEHTIIV 285
V QF+ T+++
Sbjct: 314 EFVAQFKFTVLL 325
>gb|AAD05561.1| (AF104670) cell cycle protein [Homo sapiens]
Length = 394
Score = 105 bits (260), Expect = 6e-22
Identities = 79/312 (25%), Positives = 147/312 (46%), Gaps = 33/312 (10%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKP-----------AFP 51
V K G IA +V V+ + GVS+L L EK + I+E K AFP
Sbjct: 18 VTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFP 77
Query: 52 VNLSLNEIAAHYTPYKGDET-TLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEED----- 105
++S+N H++P K D+ LKEGD +KID+GVH+DG+IA+ A T V + +
Sbjct: 78 TSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTG 137
Query: 106 ---DLMEAAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHA 162
D+++AA E+A+ + + G + ++ A PI + H+++++ +
Sbjct: 138 RKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVIDG 197
Query: 163 GISI-----PNIYRPHDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAP---- 213
+I + H+ + +V+A++ ++G G+ + +Y RD
Sbjct: 198 EKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTT-IYKRDPSKQYG 256
Query: 214 VRMVQARFLLAKIKREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRN 273
++M +R ++++R + +PF R + E + ++ + K L + VL E
Sbjct: 257 LKMKTSRAFFSEVERRFDAMPFTLRAFEDEK---KARMGVVECAKHELLQPFNVLYEKEG 313
Query: 274 GLVTQFEHTIIV 285
V QF+ T+++
Sbjct: 314 EFVAQFKFTVLL 325
>gi|11435123 proliferation-associated 2G4, 38kD [Homo sapiens]
Length = 404
Score = 105 bits (260), Expect = 6e-22
Identities = 79/312 (25%), Positives = 147/312 (46%), Gaps = 33/312 (10%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKP-----------AFP 51
V K G IA +V V+ + GVS+L L EK + I+E K AFP
Sbjct: 50 VTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFP 109
Query: 52 VNLSLNEIAAHYTPYKGDET-TLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEED----- 105
++S+N H++P K D+ LKEGD +KID+GVH+DG+IA+ A T V + +
Sbjct: 110 TSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTG 169
Query: 106 ---DLMEAAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHA 162
D+++AA E+A+ + + G + ++ A PI + H+++++ +
Sbjct: 170 RKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVIDG 229
Query: 163 GISI-----PNIYRPHDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAP---- 213
+I + H+ + +V+A++ ++G G+ + +Y RD
Sbjct: 230 EKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTT-IYKRDPSKQYG 288
Query: 214 VRMVQARFLLAKIKREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRN 273
++M +R ++++R + +PF R + E + ++ + K L + VL E
Sbjct: 289 LKMKTSRAFFSEVERRFDAMPFTLRAFEDEK---KARMGVVECAKHELLQPFNVLYEKEG 345
Query: 274 GLVTQFEHTIIV 285
V QF+ T+++
Sbjct: 346 EFVAQFKFTVLL 357
>gb|AAC34392.1| (AF056116) PAS1 [Takifugu rubripes]
Length = 392
Score = 104 bits (258), Expect = 1e-21
Identities = 84/312 (26%), Positives = 147/312 (46%), Gaps = 33/312 (10%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKP-----------AFP 51
V K IA + + V+ A G S+L L EK + I+E K AFP
Sbjct: 18 VTKFKMGADIANRKLKMVVEAAVAGTSVLSLCEKGDTYIMEEIGKIFKKEKEMKKGIAFP 77
Query: 52 VNLSLNEIAAHYTPYKGDETT-LKEGDYLKIDIGVHIDGYIADTAVTVRVGMEED----- 105
+S+N H++P K D LK+GD +KID+GVH+DG+I++ A ++ VG+ +D
Sbjct: 78 TCVSVNNCVCHFSPVKSDPNVILKDGDLVKIDLGVHVDGFISNVAHSLIVGVTKDNPQTG 137
Query: 106 ---DLMEAAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHA 162
DLM AA E+A+ + + G + ++ A + PI + H+++++ +
Sbjct: 138 RKADLMMAAHLCAEAALRLVKPGNQNTQVTEAWNKIAKSFKCAPIEGMLSHQLKQHVIDG 197
Query: 163 GISI-----PNIYRPHDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMYVRDA----P 213
+I + H+ + +V+A++ +TG G+ + +Y RD
Sbjct: 198 EKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLISTGEGKAKDGGQRTT-VYKRDPNKVYG 256
Query: 214 VRMVQARFLLAKIKREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRN 273
++M +R L + I+R + T+PF R + E + +L L K L + VL E
Sbjct: 257 LKMKSSRMLFSDIERRFDTMPFTLRAFE---EESKARLGLVECAKHELLQPFTVLYEKEG 313
Query: 274 GLVTQFEHTIIV 285
V QF+ T+++
Sbjct: 314 EFVAQFKFTVLL 325
>gb|AAF39984.1| (AC006696) contains similarity to Pfam family PF00557
(metallopeptidase family M24) score=110.2, E=3.9e-29,
N=1 [Caenorhabditis elegans]
Length = 391
Score = 104 bits (258), Expect = 1e-21
Identities = 87/318 (27%), Positives = 145/318 (45%), Gaps = 33/318 (10%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKP-----------AFP 51
V K A +I V +E + K G +L + + I+E K A P
Sbjct: 29 VTKYQVAAEITNAVLKEVLANIKEGAIAGDLCDLGDKLILEKTGKLYKKEKNFTKGIAMP 88
Query: 52 VNLSLNEIAAHYTPYKGDE-TTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEED----- 105
+S++ HYTP K + LK G +K+D+G HIDG IA A TV VG +D
Sbjct: 89 TCISIDNCICHYTPLKSEAPVVLKNGQVVKVDLGTHIDGLIATAAHTVVVGASKDNKVTG 148
Query: 106 ---DLMEAAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHA 162
DL+ +ALE AI R E + + I+ + G PI N+ H++ER ++
Sbjct: 149 KLADLLRGTHDALEIAIRSLRPDTENTTITKNIDKTAAEFGLTPIENMLSHQLERNEIDG 208
Query: 163 GISI-----PNIYRPHDNYKLREGDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAPV--- 214
I + K+ + + +AI+ +TG GQ ++ T ++ ++ V
Sbjct: 209 EKKIIQNSGEKQKGEIEKIKIDKHEAYAIDILFSTGKGQPKDM-DTRTTVFRKNEQVSYQ 267
Query: 215 -RMVQARFLLAKIKREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRN 273
+M +R + + + + +PF+ R + E+ + K+ + EK G L YPVL E
Sbjct: 268 LKMKASRVFFSDVNKVHGPMPFSLRSFEEEV---KAKMGVVECEKYGLLVPYPVLYEKEG 324
Query: 274 GLVTQFEHTIIVEKDSVI 291
LV QF+ T++V + ++
Sbjct: 325 ELVAQFKATVLVMPNGLL 342
>pir||E69810 methionine aminopeptidase homolog yflG - Bacillus subtilis
>gi|2443229|dbj|BAA22300.1| (D86417) YflG [Bacillus
subtilis] >gi|2633093|emb|CAB12598.1| (Z99108) similar
to methionine aminopeptidase [Bacillus subtilis]
Length = 249
Score = 100 bits (246), Expect = 2e-20
Identities = 69/209 (33%), Positives = 104/209 (49%), Gaps = 13/209 (6%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPA------FP--VN 53
+++ L + G+I REE + A+PG+S +L + + E GA A FP
Sbjct: 8 ELEGLKKIGRIVALAREEMKRKAEPGMSTKDLDLIGKAVLDEHGAVSAPEKEYDFPGVTC 67
Query: 54 LSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEED---DLMEA 110
+S+N+ AH P LK GD + IDI G+ +DT ++ +G E+ L +
Sbjct: 68 ISVNDEVAHGIP--STSKILKAGDLVNIDISAEFGGFYSDTGISFVLGEGEERLHKLCQC 125
Query: 111 AREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIY 170
A A + + A+AG ++GRA+ E R +GF I L+GH I R A I N Y
Sbjct: 126 AENAFQKGLQQAKAGKRQNQIGRAVYHEARSQGFTVIKTLTGHGIGRSLHEAPNHIMNYY 185
Query: 171 RPHDNYKLREGDVFAIEPFATTGAGQVIE 199
P DN + G V A+EPF +T A ++E
Sbjct: 186 DPFDNALFKNGTVIALEPFISTKAETIVE 214
>pir||T50575 methionyl aminopeptidase (EC 3.4.11.18) [imported] - Streptomyces
coelicolor >gi|6469251|emb|CAB61712.1| (AL133220)
methionine aminopeptidase (EC 3.4.11.18). [Streptomyces
coelicolor A3(2)]
Length = 285
Score = 98.7 bits (242), Expect = 7e-20
Identities = 64/202 (31%), Positives = 102/202 (49%), Gaps = 15/202 (7%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPA------FPVNL-- 54
V+ + AG+IA + EEA K PGV+ L + + GA P+ +P +L
Sbjct: 47 VEAMRVAGRIAARAMEEAAKHIAPGVTTDALDRVAHEYMCDHGAYPSTLGYRGYPKSLCS 106
Query: 55 SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDD---LMEAA 111
S+NE+ H P D T L++GD + +D+ +I G D T VG +++ L+E
Sbjct: 107 SVNEVICHGIP---DSTVLRDGDIVNLDVTAYIGGVHGDNNATYLVGEVDEESRLLVERT 163
Query: 112 REALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYR 171
RE+L AI + G +I +GR IE ++ G+ + + +GH I H+G+ +P+
Sbjct: 164 RESLTRAIKAVKPGRQINIIGRVIESYAKRFGYGVVRDFTGHGINT-SFHSGLIVPHYDS 222
Query: 172 PHDNYKLREGDVFAIEPFATTG 193
PH ++ G F IEP T G
Sbjct: 223 PHATTVIQPGMTFTIEPMLTLG 244
>gb|AAF04629.2|AF099106_1 (AF099106) p45 [Leishmania major]
Length = 361
Score = 98.3 bits (241), Expect = 1e-19
Identities = 73/261 (27%), Positives = 126/261 (47%), Gaps = 25/261 (9%)
Query: 49 AFPVNLSLNEIAAHYTPYKGDETTLKE---GDYLKIDIGVHIDGYIADTAVTVRVGMEED 105
AFP +S+N H +P DETT +E GD + D+G+H+DGY A A T++V E++
Sbjct: 69 AFPTCISVNNCVCHNSPGVSDETTQQEIAMGDVVHYDLGIHVDGYCAVVAHTIQV-TEDN 127
Query: 106 DL---------MEAAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIE 156
+L + AA L +A+ R G I ++ +E P+ + H ++
Sbjct: 128 ELGKDEKAARVITAAYNILNTALRQMRPGTTIYQVTDVVEKAAEHYKVTPVDGVLSHMMK 187
Query: 157 RYKLHAGISIPN----IYRPHDNYKLREGDVFAIEPFATTGAGQVIEVPP-TLIYMYVRD 211
RY + IP + HD Y L + V+ ++ T+G G++ E ++ D
Sbjct: 188 RYIIDGYRCIPQRRVAEHMVHD-YDLEKAQVWTLDIVMTSGKGKLKERDARPCVFKVALD 246
Query: 212 A--PVRMVQARFLLAKIKREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLR 269
+ V+M A+ + +I +Y T PFA R L+ + + +L L + K GA+ YP+L
Sbjct: 247 SNYSVKMESAKEVQKEIDSKYATFPFAIRNLEAK----KARLGLNEMAKHGAVIPYPILF 302
Query: 270 EIRNGLVTQFEHTIIVEKDSV 290
E +V F+ T+++ +
Sbjct: 303 EKEGEVVAHFKITVLISNKKI 323
>pir||A81262 methionyl aminopeptidase (EC 3.4.11.18) Cj1651c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6969068|emb|CAB73639.1| (AL139079) methionine
aminopeptidase [Campylobacter jejuni]
Length = 252
Score = 98.3 bits (241), Expect = 1e-19
Identities = 70/202 (34%), Positives = 100/202 (48%), Gaps = 19/202 (9%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFP--------VN 53
+++KL A +I K K G+SL ++ + E I+ LGAKP+F +
Sbjct: 9 EIEKLRIANQIVAKTLNFLENEIKIGMSLKQIDKMAEDYILSLGAKPSFKGLYGFPGAIC 68
Query: 54 LSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGM---EEDDLMEA 110
SLN++ H P D+ +KEGD L +D+G IDGY D A T+ +G + L+
Sbjct: 69 TSLNQVCIHGIP---DDKIIKEGDILGLDVGSLIDGYYGDAARTIAIGEVSPADKALISC 125
Query: 111 AREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIY 170
A++AL AI + R G+ KEL A+ + I RGF P+ GH I R K H I N
Sbjct: 126 AKDALYHAIDIIRDGMRFKELSAALGEFIHVRGFVPLRGYCGHGIGR-KPHGEPEILNYL 184
Query: 171 R----PHDNYKLREGDVFAIEP 188
K++ G VF IEP
Sbjct: 185 EKGASAKSGPKIKNGMVFCIEP 206
>gb|AAF91445.1|AF281652_1 (AF281652) putative DNA binding protein [Atriplex hortensis]
Length = 397
Score = 97.9 bits (240), Expect = 1e-19
Identities = 82/313 (26%), Positives = 148/313 (47%), Gaps = 39/313 (12%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRI--------------IELGAKP 48
V K A I + + V KP +++L EK + I IE G
Sbjct: 19 VTKYKSAADIVNRALQLVVGECKPKAKIVDLCEKGDNFIREQTGNMYKNVKKKIERGV-- 76
Query: 49 AFPVNLSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVT--VRVGM---E 103
AFP LS+N + H++P D++ L+EGD +KID+G HIDG+IA A T ++ G
Sbjct: 77 AFPTCLSINNVVCHFSPLASDDSVLEEGDLVKIDMGCHIDGFIAVVAHTHVIQEGPVTGR 136
Query: 104 EDDLMEAAREALESAISVARAGVEIKELGRAIEDEIRKRG----FNPIVNLSGHKIERYK 159
+ D++ A A E A+ + R G K R + + +K + + H+++++
Sbjct: 137 KADVLAATNTAAEVALRLVRPG---KNQYRCNQKQSQKXAAAYDCKIVEGVLSHQMKQFV 193
Query: 160 LHAGISIPNIYRPH---DNYKLREGDVFAIEPFATTGAG--QVIEVPPTLIYMYVRDA-- 212
+ + ++ P D+ + E +V++++ A+TG G ++++ T IY D
Sbjct: 194 IDGNKVVLSVSSPDVRVDDAEFEENEVYSVDIAASTGEGKPRMLDEKQTTIYKRAVDKNY 253
Query: 213 PVRMVQARFLLAKIKREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIR 272
++M +RF+ ++I +++ +PF R L+ E + +L L L YPVL E
Sbjct: 254 HLKMKASRFIFSEINQKFPIMPFTARALE----EKRARLGLVECVNHDLLQPYPVLYEKP 309
Query: 273 NGLVTQFEHTIIV 285
V + T+++
Sbjct: 310 GDYVAHIKFTVLL 322
>pir||F72247 methionine aminopeptidase - Thermotoga maritima (strain MSB8)
>gi|4982042|gb|AAD36544.1|AE001798_9 (AE001798)
methionine aminopeptidase [Thermotoga maritima]
Length = 250
Score = 97.5 bits (239), Expect = 2e-19
Identities = 64/208 (30%), Positives = 100/208 (47%), Gaps = 14/208 (6%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFP--------VN 53
+++K+ +AGK E K+ PG + ++ + +L KPAF
Sbjct: 9 EIEKMKKAGKAVAVALREVRKVIVPGKTAWDVETLVLEIFKKLRVKPAFKGYGGYKYATC 68
Query: 54 LSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEED---DLMEA 110
+S+NE H P K E KEGD + +D+G G D AVT VG ++ +L+
Sbjct: 69 VSVNEEVVHGLPLK--EKVFKEGDIVSVDVGAVYQGLYGDAAVTYIVGETDERGKELVRV 126
Query: 111 AREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIY 170
RE LE AI + + G+ + ++ I++ + GFN I + GH + R +LH IPN
Sbjct: 127 TREVLEKAIKMIKPGIRLGDVSHCIQETVESVGFNVIRDYVGHGVGR-ELHEDPQIPNYG 185
Query: 171 RPHDNYKLREGDVFAIEPFATTGAGQVI 198
P LR+G AIEP + G +V+
Sbjct: 186 TPGTGVVLRKGMTLAIEPMVSEGDWRVV 213
>dbj|BAB03321.1| (AB035448) methionin aminopeptidase [Staphylococcus aureus]
Length = 252
Score = 97.1 bits (238), Expect = 2e-19
Identities = 68/210 (32%), Positives = 101/210 (47%), Gaps = 15/210 (7%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPA------FPVN-- 53
++ L E G I KVR KPG++ EL + E GA A FP
Sbjct: 8 ELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQTC 67
Query: 54 LSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLME---- 109
+S+NE AH P K ++EGD + ID+ +GY ADT ++ VG +D + +
Sbjct: 68 ISVNEEVAHGIPSK---RVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCD 124
Query: 110 AAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNI 169
A A E+AI+ + G ++ +G+A+ + R+ I NL+GH + A + N
Sbjct: 125 VATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAHVLNY 184
Query: 170 YRPHDNYKLREGDVFAIEPFATTGAGQVIE 199
+ P D L EG V AIEPF ++ A V E
Sbjct: 185 FDPKDKTLLTEGMVLAIEPFISSNASFVTE 214
>sp|P19994|AMPM_BACSU METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE M) >gi|80333|pir||JS0493
methionyl aminopeptidase (EC 3.4.11.18) map - Bacillus
subtilis >gi|216341|dbj|BAA00497.1| (D00619) methionine
amino peptidase [Bacillus subtilis]
>gi|1044986|gb|AAB06821.1| (L47971) methionine
aminopeptidase [Bacillus subtilis]
>gi|2632405|emb|CAB11914.1| (Z99104) methionine
aminopeptidase [Bacillus subtilis]
Length = 248
Score = 95.2 bits (233), Expect = 8e-19
Identities = 66/201 (32%), Positives = 96/201 (46%), Gaps = 15/201 (7%)
Query: 8 EAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFP--------VNLSLNEI 59
EAG+I EE K KPG+S EL + E I + GA P+F + +S+NE
Sbjct: 15 EAGRIVALTHEELKKHIKPGISTKELDQIAERFIKKQGAIPSFKGYNGFRGSICVSVNEE 74
Query: 60 AAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDD---LMEAAREALE 116
H P LK+GD + IDIG ++GY D+A T VG DD L+E E+L
Sbjct: 75 LVHGIP---GSRVLKDGDIISIDIGAKLNGYHGDSAWTYPVGNISDDDKKLLEVTEESLY 131
Query: 117 SAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYRPHDNY 176
+ A+ G + + AI+ + F+ + GH + + LH IP+ P+
Sbjct: 132 KGLQEAKPGERLSNISHAIQTYVENEQFSVVREYVGHGVGQ-DLHEDPQIPHYGPPNKGP 190
Query: 177 KLREGDVFAIEPFATTGAGQV 197
+L+ G V AIEP G+ V
Sbjct: 191 RLKPGMVLAIEPMVNAGSRYV 211
>pir||C75410 methionine aminopeptidase - Deinococcus radiodurans (strain R1)
>gi|6459062|gb|AAF10883.1|AE001978_3 (AE001978)
methionine aminopeptidase [Deinococcus radiodurans]
Length = 259
Score = 95.2 bits (233), Expect = 8e-19
Identities = 63/207 (30%), Positives = 99/207 (47%), Gaps = 19/207 (9%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAF----------- 50
+++ + AG + + +PGV+L EL + E I GAKPA+
Sbjct: 17 EIETMRRAGGLVAETFRVLEPYVQPGVTLKELDRRAEEFIRGKGAKPAYLGYGPRNNPFP 76
Query: 51 -PVNLSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDD--- 106
+ S+NE+ H P D+ L++GD L +DIGV +DGY D T VG D+
Sbjct: 77 GTICASVNEVICHGIP---DDRELRDGDILGMDIGVLLDGYYGDACTTYTVGQVSDEVRA 133
Query: 107 LMEAAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISI 166
L++ R L++ + R G + ++G AI+ RG+ + +GH I + +LH +I
Sbjct: 134 LVDTTRACLQAGLDEVRPGAKTGDIGHAIQSLAESRGYGVVREYTGHGIGK-RLHEDPTI 192
Query: 167 PNIYRPHDNYKLREGDVFAIEPFATTG 193
+ H KL+ G VF IEP G
Sbjct: 193 YHWGVHHTGLKLQPGMVFTIEPMINLG 219
>pir||S54181 p38-2G4 protein - mouse >gi|790470|emb|CAA59260.1| (X84789) p38-2G4
[Mus musculus]
Length = 340
Score = 94.8 bits (232), Expect = 1e-18
Identities = 66/274 (24%), Positives = 133/274 (48%), Gaps = 22/274 (8%)
Query: 30 LLELAEKIEGRIIELGAKPAFPVNLSLNEIAAHYTPYKGDET-TLKEGDYLKIDIGVHID 88
++E KI + E+ AFP ++S+N H++P K D+ LKEGD +KID+GVH+D
Sbjct: 2 IMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVD 61
Query: 89 GYIADTAVTVRVGMEED--------DLMEAAREALESAISVARAGVEIKELGRAIEDEIR 140
G+IA+ A T +G+ + D+++AA E+A+ + + G + ++ A
Sbjct: 62 GFIANVAHTFVIGVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAH 121
Query: 141 KRGFNPIVNLSGHKIERYKLHAGISI-----PNIYRPHDNYKLREGDVFAIEPFATTGAG 195
PI + H+++++ + +I + H+ + +V+A++ ++G G
Sbjct: 122 SFNCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEG 181
Query: 196 QVIEVPPTLIYMYVRDAP----VRMVQARFLLAKIKREYKTLPFAYRWLQGEMPEGQLKL 251
+ + +Y RD ++M +R ++++R + +PF R + E + ++
Sbjct: 182 KAKDAGQRTT-IYKRDPSKQYGLKMKTSRAFFSEVERRFDAMPFTLRAFEDEK---KARM 237
Query: 252 ALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIV 285
+ K L + VL E V QF+ T+++
Sbjct: 238 GVVECAKHELLQPFNVLYEKEGEFVAQFKFTVLL 271
>emb|CAB16790.1| (Z99707) methionyl aminopeptidase-like protein [Arabidopsis
thaliana] >gi|7270653|emb|CAB80370.1| (AL161590)
methionyl aminopeptidase-like protein [Arabidopsis
thaliana]
Length = 305
Score = 94.0 bits (230), Expect = 2e-18
Identities = 64/197 (32%), Positives = 104/197 (52%), Gaps = 16/197 (8%)
Query: 9 AGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPA------FPVNL--SLNEIA 60
+G +A +VR+ A L KPGV+ E+ E + IIE GA P+ FP ++ S+NE
Sbjct: 74 SGILAARVRDYAGTLVKPGVTTDEIDEAVHNMIIENGAYPSPLGYGGFPKSVCTSVNECI 133
Query: 61 AHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDD---LMEAAREALES 117
H P D L++GD + ID+ V+++GY DT+ T G ++ L+E +E+L+
Sbjct: 134 CHGIP---DSRPLEDGDIINIDVTVYLNGYHGDTSATFFCGNVDEKAKKLVEVTKESLDK 190
Query: 118 AISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYRPHDNYK 177
AIS+ GVE K++G+ I D K + + GH + HA + + +R ++ +
Sbjct: 191 AISICGPGVEYKKIGKVIHDLADKHKYGVVRQFVGHGVGSV-FHADPVVLH-FRNNEAGR 248
Query: 178 LREGDVFAIEPFATTGA 194
+ F IEP T G+
Sbjct: 249 MVLNQTFTIEPMLTIGS 265
>gb|AAG33977.1|AF250963_1 (AF250963) methionine aminopeptidase-like protein [Arabidopsis
thaliana]
Length = 350
Score = 94.0 bits (230), Expect = 2e-18
Identities = 64/197 (32%), Positives = 104/197 (52%), Gaps = 16/197 (8%)
Query: 9 AGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPA------FPVNL--SLNEIA 60
+G +A +VR+ A L KPGV+ E+ E + IIE GA P+ FP ++ S+NE
Sbjct: 119 SGILAARVRDYAGTLVKPGVTTDEIDEAVHNMIIENGAYPSPLGYGGFPKSVCTSVNECI 178
Query: 61 AHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDD---LMEAAREALES 117
H P D L++GD + ID+ V+++GY DT+ T G ++ L+E +E+L+
Sbjct: 179 CHGIP---DSRPLEDGDIINIDVTVYLNGYHGDTSATFFCGNVDEKAKKLVEVTKESLDK 235
Query: 118 AISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYRPHDNYK 177
AIS+ GVE K++G+ I D K + + GH + HA + + +R ++ +
Sbjct: 236 AISICGPGVEYKKIGKVIHDLADKHKYGVVRQFVGHGVGSV-FHADPVVLH-FRNNEAGR 293
Query: 178 LREGDVFAIEPFATTGA 194
+ F IEP T G+
Sbjct: 294 MVLNQTFTIEPMLTIGS 310
>gb|AAD00646.1| (U87954) erbB3 binding protein EBP1 [Homo sapiens]
Length = 340
Score = 92.4 bits (226), Expect = 5e-18
Identities = 66/274 (24%), Positives = 132/274 (48%), Gaps = 22/274 (8%)
Query: 30 LLELAEKIEGRIIELGAKPAFPVNLSLNEIAAHYTPYKGDET-TLKEGDYLKIDIGVHID 88
++E KI + E+ AFP ++S+N H++P K D+ LKEGD +KID+GVH+D
Sbjct: 2 IMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVD 61
Query: 89 GYIADTAVTVRVGMEED--------DLMEAAREALESAISVARAGVEIKELGRAIEDEIR 140
G+IA+ A T V + + D+++AA E+A+ + + G + ++ A
Sbjct: 62 GFIANVAHTFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAH 121
Query: 141 KRGFNPIVNLSGHKIERYKLHAGISI-----PNIYRPHDNYKLREGDVFAIEPFATTGAG 195
PI + H+++++ + +I + H+ + +V+A++ ++G G
Sbjct: 122 SFNCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEG 181
Query: 196 QVIEVPPTLIYMYVRDAP----VRMVQARFLLAKIKREYKTLPFAYRWLQGEMPEGQLKL 251
+ + +Y RD ++M +R ++++R + +PF R + E + ++
Sbjct: 182 KAKDAGQRTT-IYKRDPSKQYGLKMKTSRAFFSEVERRFDAMPFTLRAFEDEK---KARM 237
Query: 252 ALRTLEKSGALYGYPVLREIRNGLVTQFEHTIIV 285
+ K L + VL E V QF+ T+++
Sbjct: 238 GVVECAKHELLQPFNVLYEKEGEFVAQFKFTVLL 271
>gb|AAG33975.1|AF250961_1 (AF250961) methionine aminopeptidase-like protein [Arabidopsis
thaliana]
Length = 369
Score = 92.1 bits (225), Expect = 7e-18
Identities = 65/210 (30%), Positives = 103/210 (48%), Gaps = 16/210 (7%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPA------FPVNL-- 54
+ K+ A ++A +V A L KP V+ E+ + + IIE GA P+ FP ++
Sbjct: 132 IAKMRAACELAARVLNYAGTLVKPSVTTNEIDKAVHDMIIEAGAYPSPLGYGGFPKSVCT 191
Query: 55 SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEED---DLMEAA 111
S+NE H P D L+ GD + ID+ V++DGY DT+ T G ++ L++
Sbjct: 192 SVNECMCHGIP---DSRQLQSGDIINIDVTVYLDGYHGDTSRTFFCGEVDEGFKQLVKVT 248
Query: 112 REALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYR 171
E LE I+V + G K++G+ I + K G+N + GH + H+ I + YR
Sbjct: 249 EECLEKGIAVCKDGASFKKIGKRISEHAEKFGYNVVERFVGHGVGPV-FHSEPLIYH-YR 306
Query: 172 PHDNYKLREGDVFAIEPFATTGAGQVIEVP 201
+ + EG F IEP T G + + P
Sbjct: 307 NDEPGLMVEGQTFTIEPILTIGTTECVTWP 336
>dbj|BAA95761.1| (AB028607) methionine aminopeptidase-like protein [Arabidopsis
thaliana]
Length = 342
Score = 91.7 bits (224), Expect = 9e-18
Identities = 72/243 (29%), Positives = 114/243 (46%), Gaps = 23/243 (9%)
Query: 5 KLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPA------FPVNL--SL 56
K+ +A ++A +V + A L +P V+ E+ + + +IE GA P+ FP ++ S+
Sbjct: 107 KMKKACELAARVLDYAGTLVRPFVTTDEIDKAVHQMVIEFGAYPSPLGYGGFPKSVCTSV 166
Query: 57 NEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEE---DDLMEAARE 113
NE H P D L+ GD + ID+ V++DGY DT+ T G L++ E
Sbjct: 167 NECMFHGIP---DSRPLQNGDIINIDVAVYLDGYHGDTSKTFLCGDVNGSLKQLVKVTEE 223
Query: 114 ALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYRPH 173
LE ISV + G K++G+ I + K G+N + GH + LH S P IY H
Sbjct: 224 CLEKGISVCKDGASFKQIGKIISEHAAKYGYN-MERFIGHGVGTV-LH---SEPLIYL-H 277
Query: 174 DNYKLR---EGDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRMVQARFLLAKIKREY 230
++Y+L EG F +EP T G + + P + P + L+ E
Sbjct: 278 NDYELEYMIEGQTFTLEPILTIGTTEFVTWPDKWTIVTADGGPAAQFEHTILITTTGAEI 337
Query: 231 KTL 233
T+
Sbjct: 338 LTI 340
>gb|AAG09564.1|AC011810_23 (AC011810) Putative methionine aminopeptidase [Arabidopsis
thaliana]
Length = 369
Score = 91.3 bits (223), Expect = 1e-17
Identities = 65/210 (30%), Positives = 103/210 (48%), Gaps = 16/210 (7%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPA------FPVNL-- 54
+ K+ A ++A +V A L KP V+ E+ + + IIE GA P+ FP ++
Sbjct: 132 IAKMRAACELAARVLNYAGTLVKPSVTTNEIDKAVHDMIIEAGAYPSPLGYGGFPKSVCT 191
Query: 55 SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDD---LMEAA 111
S+NE H P D L+ GD + ID+ V++DGY DT+ T G ++ L++
Sbjct: 192 SVNECMCHGIP---DSRQLQSGDIINIDVTVYLDGYHGDTSRTFFCGEVDEGFKRLVKVT 248
Query: 112 REALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYR 171
E LE I+V + G K++G+ I + K G+N + GH + H+ I + YR
Sbjct: 249 EECLERGIAVCKDGASFKKIGKRISEHAEKFGYNVVERFVGHGVGPV-FHSEPLIYH-YR 306
Query: 172 PHDNYKLREGDVFAIEPFATTGAGQVIEVP 201
+ + EG F IEP T G + + P
Sbjct: 307 NDEPGLMVEGQTFTIEPILTIGTTECVTWP 336
>pir||C83301 probable methionine aminopeptidase PA2748 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9948827|gb|AAG06136.1|AE004703_2 (AE004703) probable
methionine aminopeptidase [Pseudomonas aeruginosa]
Length = 260
Score = 90.9 bits (222), Expect = 2e-17
Identities = 61/208 (29%), Positives = 98/208 (46%), Gaps = 15/208 (7%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIE-LGAKPA--------FPV 52
++ ++ AG + KV E ++ +PG+S E+ E I++ L A P F V
Sbjct: 7 EIQRMSVAGALTAKVLEALDEVVRPGISTAEIDRFCERYIVDTLAAIPGSKGQYGYPFTV 66
Query: 53 NLSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVG---MEEDDLME 109
N S+NE+ H P + L++GD + +D+ V DGY D++ RVG + L++
Sbjct: 67 NTSVNEVVCHGWP--SAQQILRDGDIVNVDVTVIKDGYFGDSSKMYRVGAIDRQAQKLLD 124
Query: 110 AAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNI 169
RE L AI V R + ++G AI+ G++ + GH I R K+H + +
Sbjct: 125 VTRECLYRAIRVVRPDATLGDIGHAIQSHAEANGYSVVREYCGHGIGR-KMHEAPQVLHF 183
Query: 170 YRPHDNYKLREGDVFAIEPFATTGAGQV 197
R +L+ G F IEP G V
Sbjct: 184 GRAGAGARLKAGMTFTIEPMINQGGHAV 211
>sp|P53579|AMP1_SYNY3 PUTATIVE METHIONINE AMINOPEPTIDASE A (MAP) (PEPTIDASE M)
>gi|7435547|pir||S75731 methionyl aminopeptidase (EC
3.4.11.18) 1 - Synechocystis sp. (strain PCC 6803)
>gi|1001226|dbj|BAA10466.1| (D64003) methionine
aminopeptidase [Synechocystis sp.]
Length = 253
Score = 89.3 bits (218), Expect = 5e-17
Identities = 57/208 (27%), Positives = 103/208 (49%), Gaps = 14/208 (6%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPA------FPVNL- 54
+++K+ +AG++A + + + +PG++ LEL ++ E GA A FP ++
Sbjct: 12 EIEKMRQAGQLAAALLDHLAPMVQPGITTLELNDEAEKWTKAHGAISAPLGYNGFPKSIC 71
Query: 55 -SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEE---DDLMEA 110
S+NE+ H P++ + L+ GD + +D+ +DGY D + T VG + L++
Sbjct: 72 TSINEVICHGIPHR--KRVLQAGDIINVDVTPIVDGYHGDCSRTFFVGTPSPVAEKLVKV 129
Query: 111 AREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIY 170
E L I + G +I ++G AI+ +GF+ + + GH I + H IP+
Sbjct: 130 TEECLRLGIEAVKPGGKIGDIGAAIQSHAEAQGFSVVRDFVGHGISKI-FHTAPQIPHYG 188
Query: 171 RPHDNYKLREGDVFAIEPFATTGAGQVI 198
+ +LR G VF IEP G + +
Sbjct: 189 KAGKGKRLRPGMVFTIEPMINEGTWEAV 216
>sp|P53581|AMP3_SYNY3 PUTATIVE METHIONINE AMINOPEPTIDASE C (MAP) (PEPTIDASE M)
>gi|7435548|pir||S75743 methionyl aminopeptidase (EC
3.4.11.18) 3 - Synechocystis sp. (strain PCC 6803)
>gi|1001237|dbj|BAA10478.1| (D64003) methionine
aminopeptidase [Synechocystis sp.]
Length = 305
Score = 89.3 bits (218), Expect = 5e-17
Identities = 61/199 (30%), Positives = 99/199 (49%), Gaps = 15/199 (7%)
Query: 8 EAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAF------PVNLS--LNEI 59
+AG IA +V +E +PG++ +L + E RI LGA P+F P ++ +N
Sbjct: 67 QAGAIAAQVLKEIAATVQPGMTTGDLDQLAEERIRSLGATPSFKGYHGFPASICACVNNE 126
Query: 60 AAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGM---EEDDLMEAAREALE 116
H P + + ++ GD LK+D G + GY D+ +T+ VG + LME A AL
Sbjct: 127 VVHGIPRRRKK--IRSGDLLKVDTGAYFQGYHGDSCITIAVGKVSPQAQRLMEVAEGALY 184
Query: 117 SAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNI-YRPHDN 175
+ I + G + ++ AIED ++ G+ + +GH + + LH + N+ R N
Sbjct: 185 AGIEQVKPGNYLMDIAGAIEDYVKPTGYTIVEEFTGHGVGQ-ALHEDPHVFNVRCRDLPN 243
Query: 176 YKLREGDVFAIEPFATTGA 194
KL+ G AIEP G+
Sbjct: 244 VKLKPGMTLAIEPIVNAGS 262
>sp|Q9Z9J4|AMPM_BACHD METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE M)
>gi|11264635|pir||T44405 methionyl aminopeptidase (EC
3.4.11.18) map [imported] - Bacillus halodurans
>gi|4512426|dbj|BAA75293.1| (AB017508) map homologue
(identity of 81% to B. subtilis ) [Bacillus halodurans]
>gi|10172768|dbj|BAB03875.1| (AP001507) methionine
aminopeptidase [Bacillus halodurans]
Length = 248
Score = 89.3 bits (218), Expect = 5e-17
Identities = 62/207 (29%), Positives = 97/207 (45%), Gaps = 15/207 (7%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFP--------VN 53
+++ + EAG+I +E +PG++ +L E E I GA P+F +
Sbjct: 9 ELEIMREAGRIVALTHQEIKLHIQPGITTKKLDEIAETFIRSHGATPSFKGYNGFTGSIC 68
Query: 54 LSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGM---EEDDLMEA 110
S+NE H P LKEGD + +DIG +GY D+A T VG E+ DL++
Sbjct: 69 ASVNEELVHGIP---GNRVLKEGDIISVDIGAKYNGYHGDSAWTYAVGNISDEDQDLLDV 125
Query: 111 AREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIY 170
+L + A+AG + ++ AI+ RG+ + GH + + LH IP+
Sbjct: 126 TETSLYKGLEQAKAGARLSDISHAIQSYAEPRGYAIVREYVGHGVGQ-NLHEDPQIPHYG 184
Query: 171 RPHDNYKLREGDVFAIEPFATTGAGQV 197
P +L+ G V AIEP G+ V
Sbjct: 185 PPGKGPRLKPGMVLAIEPMVNAGSRYV 211
>gb|AAG33976.1|AF250962_1 (AF250962) methionine aminopeptidase-like protein [Arabidopsis
thaliana]
Length = 344
Score = 89.3 bits (218), Expect = 5e-17
Identities = 72/245 (29%), Positives = 112/245 (45%), Gaps = 25/245 (10%)
Query: 5 KLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPA------FPVNL--SL 56
K+ +A ++A +V + A L +P V+ E+ + + +IE GA P+ FP ++ S+
Sbjct: 107 KMKKACELAARVLDYAGTLVRPFVTTDEIDKAVHQMVIEFGAYPSPLGYGGFPKSVCTSV 166
Query: 57 NEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEE---DDLMEAARE 113
NE H P D L+ GD + ID+ V++DGY DT+ T G L++ E
Sbjct: 167 NECMFHGIP---DSRPLQNGDIINIDVAVYLDGYHGDTSKTFLCGDVNGSLKQLVKVTEE 223
Query: 114 ALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYRPH 173
LE ISV + G K++G+ I + K G+N + GH + LH S P IY H
Sbjct: 224 CLEKGISVCKDGASFKQIGKIISEHAAKYGYN-MERFIGHGLGTV-LH---SEPLIYL-H 277
Query: 174 DNYK-----LREGDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRMVQARFLLAKIKR 228
NY + EG F +EP T G + + P + P + L+
Sbjct: 278 SNYDYELEYMIEGQTFTLEPILTIGTTEFVTWPDKWTIVTADGGPAAQFEHTILITTTGA 337
Query: 229 EYKTL 233
E T+
Sbjct: 338 EILTI 342
>sp|Q09184|CDB4_SCHPO CURVED DNA-BINDING PROTEIN (42 KD PROTEIN) >gi|1076863|pir||S46583
442K curved dna-binding protein - fission yeast
(Schizosaccharomyces pombe) >gi|829085|dbj|BAA03607.1|
(D14907) 42K-protein [Schizosaccharomyces pombe]
>gi|2388928|emb|CAB11663.1| (Z98977) curved dna-binding
protein [Schizosaccharomyces pombe]
Length = 381
Score = 89.3 bits (218), Expect = 5e-17
Identities = 75/321 (23%), Positives = 145/321 (44%), Gaps = 33/321 (10%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKP----------AFPV 52
V+K AG++++ V ++ V+L +PG + ++ + + + E K AFP
Sbjct: 22 VNKYKIAGEVSQNVIKKVVELCQPGAKIYDICVRGDELLNEAIKKVYRTKDAYKGIAFPT 81
Query: 53 NLSLNEIAAHYTPYKGD---ETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGME-----E 104
+S N++AAH +P K D LK GD +KI +G HIDG+ + A T V E
Sbjct: 82 AVSPNDMAAHLSPLKSDPEANLALKSGDVVKILLGAHIDGFASLVATTTVVSEEPVTGPA 141
Query: 105 DDLMEAAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGI 164
D++ AA AL++A + G ++ ++ G P+ + H+ ER +
Sbjct: 142 ADVIAAASAALKAAQRTIKPGNTNWQVTDIVDKIATSYGCKPVAGMLSHQQEREVIDGKK 201
Query: 165 SIPNIYRPHDN-------YKLREGDVFAIEPFATTGAGQVIEVPPTLIYMYVRDAPVRMV 217
+ I P D+ + EG+V+ ++ +T ++ +Y + M+
Sbjct: 202 QV--ILNPSDSQRSEMDTFTFEEGEVYGVDILVSTSPSGKVKRSDIATRIYKKTDTTYML 259
Query: 218 Q---ARFLLAKIKREYKTLPFAYRWLQGEMPEGQLKLALRTLEKSGALYGYPVLREIRNG 274
+ +R + ++I+ ++ PF+ R + + + + L L+ Y VL + G
Sbjct: 260 KLQASRKVYSEIQTKFGPFPFSTRNISF---DSRTNMGLNECTSHKLLFPYEVLLDKDGG 316
Query: 275 LVTQFEHTIIVEKDSVIVTTE 295
+V +F TI + K I+ ++
Sbjct: 317 IVAEFYSTIALTKKGTIILSD 337
>pir||D83189 methionine aminopeptidase PA3657 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9949818|gb|AAG07045.1|AE004785_9 (AE004785)
methionine aminopeptidase [Pseudomonas aeruginosa]
Length = 261
Score = 88.9 bits (217), Expect = 6e-17
Identities = 67/204 (32%), Positives = 98/204 (47%), Gaps = 16/204 (7%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRII-ELGAKPA------FPVNL 54
D++K+ AG++A +V E + KPGV+ EL I+ E A PA FP ++
Sbjct: 10 DIEKMRIAGRLAAEVLEMIGEHIKPGVTTEELDRICHDYIVNEQKAIPAPLNYKGFPKSI 69
Query: 55 --SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEE---DDLME 109
S+N + H P +E LKEGD L +DI V DGY DT+ VG D L +
Sbjct: 70 CTSINHVVCHGIP---NEKPLKEGDILNVDITVIKDGYHGDTSKMFLVGKTPEWADRLCQ 126
Query: 110 AAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNI 169
+E + ISV R G + ++G I+ K GF+ + GH I + H + +
Sbjct: 127 ITQECMYKGISVVRPGAHLGDIGEIIQKHAEKNGFSVVREYCGHGIGKV-FHEEPQVLHY 185
Query: 170 YRPHDNYKLREGDVFAIEPFATTG 193
R +L+EG +F IEP G
Sbjct: 186 GRAGTGIELKEGMIFTIEPMINQG 209
>sp|O51132|AMPM_BORBU METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE M)
>gi|7435558|pir||A70113 methionine aminopeptidase (map)
homolog - Lyme disease spirochete
>gi|2687996|gb|AAC66499.1| (AE001123) methionine
aminopeptidase (map) [Borrelia burgdorferi]
Length = 251
Score = 88.5 bits (216), Expect = 8e-17
Identities = 63/175 (36%), Positives = 90/175 (51%), Gaps = 16/175 (9%)
Query: 26 PGVSLLELAEKIEGRIIELGAKPAFP--------VNLSLNEIAAHYTPYKGDETTLKEGD 77
PG+S EL II+ AKPAF + S+NE H P K L +GD
Sbjct: 35 PGISTKELDLIAYDFIIKNRAKPAFKGYRGFKGTICASVNEEVIHGIPGK---RKLADGD 91
Query: 78 YLKIDIGVHIDGYIADTAVTVRVGMEE---DDLMEAAREALESAISVARAGVEIKELGRA 134
+ ID GV +DG+ +D A T +VG + D L+E +L I+ + G I + +A
Sbjct: 92 IVSIDCGVILDGFYSDMAKTFKVGNVDSSIDKLLEVTNASLYKGIAEMKVGNRILNISKA 151
Query: 135 IEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYRP-HDNYKLREGDVFAIEP 188
IED I+ GF + +GH + ++LH S+PN Y P N +++EG V AIEP
Sbjct: 152 IEDYIKPFGFGIVREYTGHGV-GFELHEEPSVPNYYAPFFKNIRIQEGMVLAIEP 205
>pir||T34903 methionine aminopeptidase - Streptomyces coelicolor
>gi|3218361|emb|CAA19620.1| (AL023861) methionine
aminopeptidase [Streptomyces coelicolor A3(2)]
Length = 258
Score = 87.8 bits (214), Expect = 1e-16
Identities = 66/208 (31%), Positives = 97/208 (45%), Gaps = 21/208 (10%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGA-------KPAFP---- 51
+D + AG++ + + A GVSLLEL + E GA +P+F
Sbjct: 10 IDAMHAAGQVVARALTAVRQAADVGVSLLELDAVAHEVLREAGAGSPFLGYRPSFAPTPF 69
Query: 52 ---VNLSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEED--- 105
+ S+N+ H P D L++GD + ID G +DG+ D+A++ VG
Sbjct: 70 PGVICASVNDAIVHGIP---DGYRLRDGDLVSIDCGALLDGWAGDSALSFVVGTPRPADV 126
Query: 106 DLMEAAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGIS 165
L+E A ALE+ I+ A G I ++ AI R G+ + + GH I R+ +H
Sbjct: 127 TLIETAERALEAGIAAAVVGNRIGDIAHAIGTVCRSAGYGIMEDFGGHGIGRH-MHEDPG 185
Query: 166 IPNIYRPHDNYKLREGDVFAIEPFATTG 193
+PN RP LR G V AIEP T G
Sbjct: 186 VPNEGRPGRGLPLRHGMVLAIEPMLTAG 213
>gi|6323273 methionine aminopeptidase; Map1p [Saccharomyces cerevisiae]
>gi|1351928|sp|Q01662|AMP1_YEAST METHIONINE
AMINOPEPTIDASE 1 PRECURSOR (METAP 1) (PEPTIDASE M 1)
(MAP) >gi|1363808|pir||S59390 methionyl aminopeptidase
(EC 3.4.11.18) MAP1 precursor - yeast (Saccharomyces
cerevisiae) >gi|662342|gb|AAB67398.1| (U20865) Map1p:
methionine aminopeptidase [Saccharomyces cerevisiae]
>gi|975723|gb|AAA75193.1| (M77092) methionine
aminopeptidase I [Saccharomyces cerevisiae]
Length = 387
Score = 87.4 bits (213), Expect = 2e-16
Identities = 61/203 (30%), Positives = 99/203 (48%), Gaps = 16/203 (7%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPA------FPVNL-- 54
+ K+ +A + ++V + A +PG++ EL E + I+ GA P+ FP +L
Sbjct: 135 IKKIRKACMLGREVLDIAAAHVRPGITTDELDEIVHNETIKRGAYPSPLNYYNFPKSLCT 194
Query: 55 SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVG----MEEDDLMEA 110
S+NE+ H P D+T LKEGD + +D+ ++ GY AD T VG E + E
Sbjct: 195 SVNEVICHGVP---DKTVLKEGDIVNLDVSLYYQGYHADLNETYYVGENISKEALNTTET 251
Query: 111 AREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIY 170
+RE L+ AI + + G +ELG IE + + + GH + + H +IP+
Sbjct: 252 SRECLKLAIKMCKPGTTFQELGDHIEKHATENKCSVVRTYCGHGVGEF-FHCSPNIPHYA 310
Query: 171 RPHDNYKLREGDVFAIEPFATTG 193
+ ++ G VF IEP G
Sbjct: 311 KNRTPGVMKPGMVFTIEPMINEG 333
>sp|O33343|AMPM_MYCTU METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE M)
>gi|7435545|pir||G70885 probable map protein -
Mycobacterium tuberculosis (strain H37RV)
>gi|2612806|emb|CAA15523.1| (AL008883) map
[Mycobacterium tuberculosis]
Length = 285
Score = 87.4 bits (213), Expect = 2e-16
Identities = 63/203 (31%), Positives = 97/203 (47%), Gaps = 15/203 (7%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPA------FPVNL-- 54
++K+ AG+IA EA K PGV+ EL +++ GA P+ FP +
Sbjct: 47 IEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCT 106
Query: 55 SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDD---LMEAA 111
SLNE+ H P D T + +GD + ID+ +I G DT T G D+ L++
Sbjct: 107 SLNEVICHGIP---DSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRT 163
Query: 112 REALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYR 171
REA AI+ + G + +GR IE + G+N + + +GH I H G+ + + +
Sbjct: 164 REATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGT-TFHNGLVVLHYDQ 222
Query: 172 PHDNYKLREGDVFAIEPFATTGA 194
P ++ G F IEP GA
Sbjct: 223 PAVETIMQPGMTFTIEPMINLGA 245
>sp|P53580|AMP2_SYNY3 PUTATIVE METHIONINE AMINOPEPTIDASE B (MAP) (PEPTIDASE M)
>gi|7435546|pir||S76999 methionyl aminopeptidase (EC
3.4.11.18) 2 - Synechocystis sp. (strain PCC 6803)
>gi|1001810|dbj|BAA10691.1| (D64005) methionine
aminopeptidase [Synechocystis sp.]
Length = 274
Score = 87.0 bits (212), Expect = 2e-16
Identities = 59/208 (28%), Positives = 101/208 (48%), Gaps = 19/208 (9%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGA--------KPAFP-- 51
++DK+ G++A + + +PGVS L ++ + + GA P +P
Sbjct: 29 ELDKMRRVGQLAANLLNHLESMVQPGVSTQALNDEATRWMEDHGAISATLGYAPPGYPPF 88
Query: 52 ---VNLSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDD-- 106
+ S+NE+ H P + LK+GD + ID+ + + GY DT+ T VG
Sbjct: 89 TGAICTSINEVVCHGIP--NPKQILKDGDIINIDVTLRLAGYHGDTSRTFLVGSVSATAR 146
Query: 107 -LMEAAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGIS 165
L+EA +E++ I+ + G I ++G AI+ GF+ + ++ GH I R ++H +
Sbjct: 147 KLVEATQESMMRGIAEIKPGARIGDIGAAIQAYAEASGFSVVRDMVGHGIGR-QMHTELQ 205
Query: 166 IPNIYRPHDNYKLREGDVFAIEPFATTG 193
IP+ + KLR G VF +EP G
Sbjct: 206 IPHYGKRGSGLKLRPGMVFTVEPMLNEG 233
>gb|AAF52949.1| (AE003628) CG5188 gene product [Drosophila melanogaster]
Length = 307
Score = 85.4 bits (208), Expect = 7e-16
Identities = 62/208 (29%), Positives = 101/208 (47%), Gaps = 16/208 (7%)
Query: 1 MDVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPA------FPVNL 54
+ +D + +G++A ++ E KLA G + ++ RI+E A P+ FP ++
Sbjct: 67 VQIDAMRLSGRLAARILRECGKLATVGTTTDQIDAFAHERILESKAYPSPLRYAGFPKSI 126
Query: 55 --SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDD---LME 109
S+N IA H P D+ L +GD + ID+ V ++GY D + T RVG ++ L+E
Sbjct: 127 CTSINNIACHGIP---DDRQLADGDIINIDVTVFLNGYHGDCSETFRVGNVDERGGFLVE 183
Query: 110 AAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNI 169
A + L+ IS+ GVE E+G+ I+ + I GH I Y H I +
Sbjct: 184 ATKSCLDQCISLCGPGVEFNEIGKFIDRYCDEHDLASIAAFIGHGIGSY-FHGPPEILHY 242
Query: 170 YRPHDNYKLREGDVFAIEPFATTGAGQV 197
Y K++ G F IEP + G ++
Sbjct: 243 YNEIPG-KMQPGMTFTIEPILSLGGAEI 269
>pir||A70823 probable methionine amino peptidase - Mycobacterium tuberculosis
(strain H37RV) >gi|2911008|emb|CAA17501.1| (AL021958)
map' [Mycobacterium tuberculosis]
>gi|4191726|gb|AAD09883.1| (U77912) methionine
aminopeptidase [Mycobacterium bovis]
Length = 266
Score = 84.3 bits (205), Expect = 2e-15
Identities = 66/214 (30%), Positives = 95/214 (43%), Gaps = 20/214 (9%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAF------PVNL- 54
++D + AG + A PG S L L E E I E GA P+F P ++
Sbjct: 20 ELDAMAAAGAVVAAALRAIRAAAAPGTSSLSLDEIAESVIRESGATPSFLGYHGYPASIC 79
Query: 55 -SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGM---EEDDLMEA 110
S+N+ H P + L GD + ID G +DG+ D A+T VG ++ L EA
Sbjct: 80 ASINDRVVHGIPSTAE--VLAPGDLVSIDCGAVLDGWHGDAAITFGVGALSDADEALSEA 137
Query: 111 AREALESAISVARAGVEIKELGRAIEDEIRK------RGFNPIVNLSGHKIERYKLHAGI 164
RE+L++ I+ G + ++ AIE R R F + GH I R ++H
Sbjct: 138 TRESLQAGIAAMVVGNRLTDVAHAIETGTRAAELRYGRSFGIVAGYGGHGIGR-QMHMDP 196
Query: 165 SIPNIYRPHDNYKLREGDVFAIEPFATTGAGQVI 198
+PN P L G V AIEP T G + +
Sbjct: 197 FLPNEGAPGRGPLLAAGSVLAIEPMLTLGTTKTV 230
>pir||T45391 methionine aminopeptidase [imported] - Mycobacterium leprae
>gi|2344859|emb|CAB11461.1| (Z98756) methionine
aminopeptidase [Mycobacterium leprae]
Length = 266
Score = 82.7 bits (201), Expect = 5e-15
Identities = 69/214 (32%), Positives = 96/214 (44%), Gaps = 20/214 (9%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAF--------PVN 53
++D + AG + A PGVS L L E E I E GA P+F +
Sbjct: 20 ELDAMAAAGAVVAAALHAVRDAAGPGVSSLSLDEIAESVIREAGATPSFLRYHGYPATIC 79
Query: 54 LSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVG---MEEDDLMEA 110
S+N+ H P + L GD + ID G +DG+ D A+T VG ++ L +A
Sbjct: 80 TSVNDRVIHGIPSAVE--ILAPGDLVSIDCGAVLDGWHGDAAITFGVGTLTSVDEALSQA 137
Query: 111 AREALESAISVARAGVEIKELGRAIE-----DEIRKR-GFNPIVNLSGHKIERYKLHAGI 164
RE+LE+ I+ + ++ AIE EIR R F + GH I R+ +H
Sbjct: 138 TRESLEAGIAAMIVNNRLTDVAHAIEVSTRTSEIRYRLTFGIVQGYGGHGIGRH-MHMDP 196
Query: 165 SIPNIYRPHDNYKLREGDVFAIEPFATTGAGQVI 198
+PN P L G V AIEP T G G+ I
Sbjct: 197 FLPNEGAPGRGPLLVPGSVLAIEPMLTLGTGKTI 230
>sp|Q9Z6Q0|AMPM_CHLPN METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE M)
>gi|7435564|pir||E72008 methionine aminopeptidase -
Chlamydophila pneumoniae (strain CWL029)
>gi|4377339|gb|AAD19146.1| (AE001681) Methionine
Aminopeptidase [Chlamydophila pneumoniae CWL029]
>gi|8979382|dbj|BAA99216.1| (AP002548) methionine
aminopeptidase [Chlamydophila pneumoniae J138]
Length = 291
Score = 82.7 bits (201), Expect = 5e-15
Identities = 59/210 (28%), Positives = 102/210 (48%), Gaps = 18/210 (8%)
Query: 5 KLIEAGKIAKKVREEAVKLAKPGVS---LLELAEKIEGRIIELGA-----KPAFPVNL-- 54
K+ A +I ++ +E K ++ GV+ L EL++++ + + A P FP +
Sbjct: 51 KIYNACQITARILDELCKASQKGVTTNELDELSQELHKKYDAIAAPFHYGSPPFPKTICT 110
Query: 55 SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEED---DLMEAA 111
SLNE+ H P ++ LK+GD + ID+ +DGY D + V +G + + +AA
Sbjct: 111 SLNEVICHGIP---NDIPLKDGDIMNIDVSCIVDGYYGDCSRMVMIGEVPEIKKKICQAA 167
Query: 112 REALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYR 171
E L +I++ + G+ + E+G AIE GF+ + GH + + H +P+ YR
Sbjct: 168 LECLNDSIAILKPGIPLCEIGEAIEARADTYGFSVVDQFVGHGV-GIEFHENPYVPH-YR 225
Query: 172 PHDNYKLREGDVFAIEPFATTGAGQVIEVP 201
L G +F IEP G + + P
Sbjct: 226 NRSMIPLAPGMIFTIEPMINVGKKEGVVDP 255
>pir||A81531 methionine aminopeptidase CP0844 [imported] - Chlamydophila
pneumoniae (strain AR39) >gi|7189756|gb|AAF38634.1|
(AE002244) methionine aminopeptidase [Chlamydophila
pneumoniae AR39]
Length = 266
Score = 82.7 bits (201), Expect = 5e-15
Identities = 59/210 (28%), Positives = 102/210 (48%), Gaps = 18/210 (8%)
Query: 5 KLIEAGKIAKKVREEAVKLAKPGVS---LLELAEKIEGRIIELGA-----KPAFPVNL-- 54
K+ A +I ++ +E K ++ GV+ L EL++++ + + A P FP +
Sbjct: 26 KIYNACQITARILDELCKASQKGVTTNELDELSQELHKKYDAIAAPFHYGSPPFPKTICT 85
Query: 55 SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEED---DLMEAA 111
SLNE+ H P ++ LK+GD + ID+ +DGY D + V +G + + +AA
Sbjct: 86 SLNEVICHGIP---NDIPLKDGDIMNIDVSCIVDGYYGDCSRMVMIGEVPEIKKKICQAA 142
Query: 112 REALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYR 171
E L +I++ + G+ + E+G AIE GF+ + GH + + H +P+ YR
Sbjct: 143 LECLNDSIAILKPGIPLCEIGEAIEARADTYGFSVVDQFVGHGV-GIEFHENPYVPH-YR 200
Query: 172 PHDNYKLREGDVFAIEPFATTGAGQVIEVP 201
L G +F IEP G + + P
Sbjct: 201 NRSMIPLAPGMIFTIEPMINVGKKEGVVDP 230
>sp|P53582|AMP1_HUMAN PUTATIVE METHIONINE AMINOPEPTIDASE 1 (METAP 1) (PEPTIDASE M 1)
(KIAA0094) >gi|577315|dbj|BAA07679.1| (D42084) KIAA0094
gene product is related to S.cerevisiae methionine
aminopeptidase. [Homo sapiens]
Length = 394
Score = 81.9 bits (199), Expect = 8e-15
Identities = 58/207 (28%), Positives = 97/207 (46%), Gaps = 17/207 (8%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFPVNL------- 54
D++ + ++A++V + A + KPGV+ E+ + I P+ P+N
Sbjct: 143 DIEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACIARNCYPS-PLNYYNFPKSC 201
Query: 55 --SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDD---LME 109
S+NE+ H P D L+EGD + +DI ++ +GY D T VG +D L++
Sbjct: 202 CTSVNEVICHGIP---DRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGEVDDGARKLVQ 258
Query: 110 AAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNI 169
E L AI + GV +ELG I+ + GF+ + + GH I + H ++P+
Sbjct: 259 TTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKL-FHTAPNVPHY 317
Query: 170 YRPHDNYKLREGDVFAIEPFATTGAGQ 196
+ ++ G VF IEP G Q
Sbjct: 318 AKNKAVGVMKSGHVFTIEPMICEGGWQ 344
>sp|P07906|AMPM_ECOLI METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE M) >gi|67532|pir||DPECM
methionyl aminopeptidase (EC 3.4.11.18) [validated] -
Escherichia coli >gi|494313|pdb|1MAT| Methionine
Aminopeptidase (E.C.3.4.11.18) >gi|146727|gb|AAA24112.1|
(M15106) methionine amino peptidase [Escherichia coli]
>gi|473823|dbj|BAA05612.1| (D26562) 'methionine
aminopeptidase' [Escherichia coli]
>gi|1552745|gb|AAB08597.1| (U70214) methionine
aminopeptidase [Escherichia coli]
>gi|1786364|gb|AAC73279.1| (AE000126) methionine
aminopeptidase [Escherichia coli K12]
Length = 264
Score = 81.1 bits (197), Expect = 1e-14
Identities = 63/208 (30%), Positives = 98/208 (46%), Gaps = 15/208 (7%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRII-ELGAKPA------FP--V 52
D++K+ AG++A +V E KPGVS EL I+ E A A +P V
Sbjct: 10 DIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSV 69
Query: 53 NLSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEE---DDLME 109
+S+NE+ H P D LK+GD + ID+ V DG+ DT+ VG + L
Sbjct: 70 CISINEVVCHGIP--DDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCR 127
Query: 110 AAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNI 169
+E+L A+ + + G+ ++E+G AI+ + GF+ + GH I R H + +
Sbjct: 128 ITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGR-GFHEEPQVLHY 186
Query: 170 YRPHDNYKLREGDVFAIEPFATTGAGQV 197
N L+ G F IEP G ++
Sbjct: 187 DSRETNVVLKPGMTFTIEPMVNAGKKEI 214
>sp|O83814|AMPM_TREPA METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE M)
>gi|7435560|pir||B71273 probable methionine
aminopeptidase (map) - syphilis spirochete
>gi|3323157|gb|AAC65810.1| (AE001255) methionine
aminopeptidase (map) [Treponema pallidum]
Length = 255
Score = 80.0 bits (194), Expect = 3e-14
Identities = 59/206 (28%), Positives = 96/206 (45%), Gaps = 15/206 (7%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPA-----FPVN--LS 55
+D + + K ++ + + L KPGV EL + I +G PA FP +S
Sbjct: 10 IDGIRASCKALARLFDVLIPLVKPGVQTQELDAFCQRFIRSVGGVPAWFSEGFPAAACIS 69
Query: 56 LNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVG---MEEDDLMEAAR 112
+NE H P +++GD + +D+G++++GYI+D TV VG E +L+
Sbjct: 70 INEEVIHGLP---SARVIQDGDLVSLDVGINLNGYISDACRTVPVGGVAHERLELLRVTT 126
Query: 113 EALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNI-YR 171
E L + I RAG ++ + RA+ + F + GH + +H +IPN+
Sbjct: 127 ECLRAGIKACRAGARVRAVSRAVYAVAARHRFGVVYEYCGHGV-GLAVHEEPNIPNVPGL 185
Query: 172 PHDNYKLREGDVFAIEPFATTGAGQV 197
N + G V AIEP T G +V
Sbjct: 186 EGPNPRFLPGMVVAIEPMLTLGTDEV 211
>pdb|2MAT|A Chain A, E.Coli Methionine Aminopeptidase At 1.9 Angstrom
Resolution
Length = 264
Score = 79.6 bits (193), Expect = 4e-14
Identities = 62/208 (29%), Positives = 98/208 (46%), Gaps = 15/208 (7%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRII-ELGAKPA------FP--V 52
D++K+ AG++A +V E KPGVS EL I+ E A A +P V
Sbjct: 10 DIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSV 69
Query: 53 NLSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEE---DDLME 109
+S+NE+ H P D LK+GD + ID+ V DG+ DT+ VG + L
Sbjct: 70 CISINEVVCHGIP--DDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCR 127
Query: 110 AAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNI 169
+E+L A+ + + G+ ++E+G AI+ + GF+ + GH I + H + +
Sbjct: 128 ITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGQ-GFHEEPQVLHY 186
Query: 170 YRPHDNYKLREGDVFAIEPFATTGAGQV 197
N L+ G F IEP G ++
Sbjct: 187 DSRETNVVLKPGMTFTIEPMVNAGKKEI 214
>pdb|1C22|A Chain A, E. Coli Methionine Aminopeptidase: Trifluoromethionine
Complex >gi|6573514|pdb|1C23|A Chain A, E. Coli
Methionine Aminopeptidase: Methionine Phosphonate
Complex >gi|6573515|pdb|1C24|A Chain A, E. Coli
Methionine Aminopeptidase: Methionine Phosphinate
Complex >gi|6573394|pdb|1C27|A Chain A, E. Coli
Methionine Aminopeptidase:norleucine Phosphonate Complex
>gi|6573512|pdb|1C21|A Chain A, E. Coli Methionine
Aminopeptidase: Methionine Complex
Length = 263
Score = 79.6 bits (193), Expect = 4e-14
Identities = 62/208 (29%), Positives = 98/208 (46%), Gaps = 15/208 (7%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRII-ELGAKPA------FP--V 52
D++K+ AG++A +V E KPGVS EL I+ E A A +P V
Sbjct: 9 DIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSV 68
Query: 53 NLSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEE---DDLME 109
+S+NE+ H P D LK+GD + ID+ V DG+ DT+ VG + L
Sbjct: 69 CISINEVVCHGIP--DDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCR 126
Query: 110 AAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNI 169
+E+L A+ + + G+ ++E+G AI+ + GF+ + GH I + H + +
Sbjct: 127 ITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGQ-GFHEEPQVLHY 185
Query: 170 YRPHDNYKLREGDVFAIEPFATTGAGQV 197
N L+ G F IEP G ++
Sbjct: 186 DSRETNVVLKPGMTFTIEPMVNAGKKEI 213
>pdb|3MAT|A Chain A, E.Coli Methionine Aminopeptidase Transition-State
Inhibitor Complex
Length = 265
Score = 79.6 bits (193), Expect = 4e-14
Identities = 62/208 (29%), Positives = 98/208 (46%), Gaps = 15/208 (7%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRII-ELGAKPA------FP--V 52
D++K+ AG++A +V E KPGVS EL I+ E A A +P V
Sbjct: 10 DIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSV 69
Query: 53 NLSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEE---DDLME 109
+S+NE+ H P D LK+GD + ID+ V DG+ DT+ VG + L
Sbjct: 70 CISINEVVCHGIP--DDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCR 127
Query: 110 AAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNI 169
+E+L A+ + + G+ ++E+G AI+ + GF+ + GH I + H + +
Sbjct: 128 ITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGQ-GFHEEPQVLHY 186
Query: 170 YRPHDNYKLREGDVFAIEPFATTGAGQV 197
N L+ G F IEP G ++
Sbjct: 187 DSRETNVVLKPGMTFTIEPMVNAGKKEI 214
>pdb|4MAT|A Chain A, E.Coli Methionine Aminopeptidase His79ala Mutant
Length = 278
Score = 79.6 bits (193), Expect = 4e-14
Identities = 62/208 (29%), Positives = 98/208 (46%), Gaps = 15/208 (7%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRII-ELGAKPA------FP--V 52
D++K+ AG++A +V E KPGVS EL I+ E A A +P V
Sbjct: 10 DIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSV 69
Query: 53 NLSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEE---DDLME 109
+S+NE+ H P D LK+GD + ID+ V DG+ DT+ VG + L
Sbjct: 70 CISINEVVCHGIP--DDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCR 127
Query: 110 AAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNI 169
+E+L A+ + + G+ ++E+G AI+ + GF+ + GH I + H + +
Sbjct: 128 ITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGQ-GFHEEPQVLHY 186
Query: 170 YRPHDNYKLREGDVFAIEPFATTGAGQV 197
N L+ G F IEP G ++
Sbjct: 187 DSRETNVVLKPGMTFTIEPMVNAGKKEI 214
>pir||D82097 methionine aminopeptidase VC2261 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9656823|gb|AAF95405.1|
(AE004298) methionine aminopeptidase [Vibrio cholerae]
Length = 280
Score = 78.4 bits (190), Expect = 9e-14
Identities = 68/220 (30%), Positives = 103/220 (45%), Gaps = 29/220 (13%)
Query: 1 MDVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIEL-GAKPA------FPVN 53
++++K+ AG++A +V E K GV+ EL + I E+ GA PA FP +
Sbjct: 9 VEIEKMRVAGRLAAEVLEMIEPHVKAGVTTEELDQICHKYITEVQGAIPAPLNYHGFPKS 68
Query: 54 L--SLNEIAAHYTPYKGDE--------TTLKEGDYLKIDIGVHIDGYIADTAVTVRVG-- 101
+ S+N I H P D L++GD L IDI V DGY DT+ +G
Sbjct: 69 ICTSINHIVCHGIPASEDTYFGQIQRPAVLRDGDILNIDITVIKDGYHGDTSKMFLIGDV 128
Query: 102 -MEEDDLMEAAREALESAISVARAGVEIKELGRAIEDEIRKRG-------FNPIVNLSGH 153
+E+ L A+E L A+ + GV++ E+G IE I+ F+ + + GH
Sbjct: 129 SIEDKRLCHVAQECLYLALKQVKPGVQLGEIGTTIEKHIKTNNKNNPRFKFSIVRDYCGH 188
Query: 154 KIERYKLHAGISIPNIYRPHDNYKLREGDVFAIEPFATTG 193
I + H + + Y+ D LREG +F IEP G
Sbjct: 189 GIGA-EFHEEPQVVH-YKNSDRTVLREGMIFTIEPMINAG 226
>sp|Q9ZCD3|AMPM_RICPR METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE M)
>gi|7435544|pir||A71644 methionine aminopeptidase (map)
RP824 - Rickettsia prowazekii
>gi|3861350|emb|CAA15249.1| (AJ235273) METHIONINE
AMINOPEPTIDASE (map) [Rickettsia prowazekii]
Length = 259
Score = 78.0 bits (189), Expect = 1e-13
Identities = 59/203 (29%), Positives = 94/203 (46%), Gaps = 15/203 (7%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPA------FPVNL- 54
D K+ AGK+A + + KP V+ L + I A PA FP ++
Sbjct: 10 DFIKMRAAGKLAAETLDFITDHVKPNVTTNSLNDLCHNFITSHNAIPAPLNYKGFPKSIC 69
Query: 55 -SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVG---MEEDDLMEA 110
S+N + H P ++ LK GD + ID+ V +DG+ DT+ VG ++ L++
Sbjct: 70 TSINHVVCHGIP---NDKPLKNGDIVNIDVTVILDGWYGDTSRMYYVGDVAIKPKRLIQV 126
Query: 111 AREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIY 170
+A+ I V R G ++ ++G AI+ K ++ + + +GH I R H SI N
Sbjct: 127 TYDAMMKGIEVVRPGAKLGDIGYAIQSYAEKHNYSVVRDYTGHGIGRV-FHDKPSILNYG 185
Query: 171 RPHDNYKLREGDVFAIEPFATTG 193
R L+EG F +EP G
Sbjct: 186 RNGTGLTLKEGMFFTVEPMINAG 208
>sp|P44421|AMPM_HAEIN METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE M)
>gi|1075015|pir||C64138 methionyl aminopeptidase (EC
3.4.11.18) - Haemophilus influenzae (strain Rd KW20)
>gi|1574578|gb|AAC23368.1| (U32845) methionine
aminopeptidase (map) [Haemophilus influenzae Rd]
Length = 268
Score = 76.1 bits (184), Expect = 5e-13
Identities = 64/210 (30%), Positives = 97/210 (45%), Gaps = 18/210 (8%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKI--EGRIIELGAKPA------FP-- 51
++ KL EA K+A V K GV+ EL ++I E + E PA FP
Sbjct: 10 EIVKLREACKLASDVLVMIEPYVKAGVTTGEL-DRICHEYMVNEQKVIPACLNYHGFPKA 68
Query: 52 VNLSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEED----DL 107
+S+NE+ H P D+ LK GD + ID+ V DGY D + VG E + L
Sbjct: 69 TCISINEVVCHGIP--SDDKVLKNGDIVNIDVTVIKDGYFGDNSKMYIVGGETNIRSKKL 126
Query: 108 MEAAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIP 167
+EAA+EAL I + + + E+G+A++ + F+ + GH + + H +
Sbjct: 127 VEAAQEALYVGIRTVKPDIRLNEIGKAVQKYTESQTFSVVREYCGHGVGT-EFHCEPQVL 185
Query: 168 NIYRPHDNYKLREGDVFAIEPFATTGAGQV 197
+ Y L+ G VF IEP G +V
Sbjct: 186 HYYADDGGVILKPGMVFTIEPMINAGKKEV 215
>gb|AAB82638.1| (AC002387) putative methionine aminopeptidase [Arabidopsis
thaliana] >gi|11320954|gb|AAG33974.1|AF250960_1
(AF250960) methionine aminopeptidase-like protein
[Arabidopsis thaliana]
Length = 398
Score = 75.7 bits (183), Expect = 6e-13
Identities = 55/203 (27%), Positives = 92/203 (45%), Gaps = 17/203 (8%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFPVNL-------- 54
+ ++ E KIA++V + A ++ PGV+ E+ + I G P+ P+N
Sbjct: 147 IQRMRETCKIAREVLDAAARVIHPGVTTDEIDRVVHEATIAAGGYPS-PLNYYFFPKSCC 205
Query: 55 -SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEED---DLMEA 110
S+NE+ H P D L++GD + +D+ V G D T VG ++ L++
Sbjct: 206 TSVNEVICHGIP---DARKLEDGDIVNVDVTVCYKGCHGDLNETYFVGNVDEASRQLVKC 262
Query: 111 AREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIY 170
E LE AI++ + GV +E+G + G + + + GH I H +IP+
Sbjct: 263 TYECLEKAIAIVKPGVRFREIGEIVNRHATMSGLSVVRSYCGHGIGDL-FHCAPNIPHYA 321
Query: 171 RPHDNYKLREGDVFAIEPFATTG 193
R ++ G F IEP G
Sbjct: 322 RNKAVGVMKAGQTFTIEPMINAG 344
>gb|AAF56327.1| (AE003749) CG13630 gene product [Drosophila melanogaster]
Length = 374
Score = 75.3 bits (182), Expect = 8e-13
Identities = 53/204 (25%), Positives = 94/204 (45%), Gaps = 17/204 (8%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFPVNL------- 54
+++ + AG++ ++ +E K + G++ EL + IE P+ P+N
Sbjct: 122 EIEGMRVAGRLGRECLDEGAKAVEVGITTDELDRLVHEAAIERECYPS-PLNYYNFPKSC 180
Query: 55 --SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDD---LME 109
S+NE+ H P D+ L++GD ID+ V+ G+ D T VG + L++
Sbjct: 181 CTSVNEVICHGIP---DQRPLQDGDLCNIDVTVYHRGFHGDLNETFFVGNVSEKHKKLVQ 237
Query: 110 AAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNI 169
EAL AI R G + +++G I+ + GF+ + + GH I R H ++P+
Sbjct: 238 VTHEALSKAIEFVRPGEKYRDIGNVIQKYVAPHGFSVVRSYCGHGIHRV-FHTAPNVPHY 296
Query: 170 YRPHDNYKLREGDVFAIEPFATTG 193
+ + G F IEP + G
Sbjct: 297 AKNSAVGVMAPGHCFTIEPMISVG 320
>pir||E82917 methionine aminopeptidase (map) UU252 [imported] - Ureaplasma
urealyticum >gi|6899222|gb|AAF30661.1|AE002122_30
(AE002122) methionine aminopeptidase (map) [Ureaplasma
urealyticum]
Length = 249
Score = 74.9 bits (181), Expect = 1e-12
Identities = 62/207 (29%), Positives = 100/207 (47%), Gaps = 20/207 (9%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIEL-GAKPAFP--------V 52
D+ + EA +I K RE K AK GVSL EL + + +IE G AF +
Sbjct: 9 DIAAIKEAVRIWKIAREAIYKQAKAGVSLKEL-DLLAKEVIEANGGIAAFHNYLGFKGHI 67
Query: 53 NLSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRV---GMEEDDLME 109
+S+NE H P + LK+GD + D+GV D + D A T+ + +E + E
Sbjct: 68 CISVNECVIHGVP---TDYVLKDGDKVTFDVGVKYDNHYCDAAFTIIINNSNVEALKISE 124
Query: 110 AAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNI 169
+++++ A+++ + V + AI+ I K G+ + + +GH ++H IPN
Sbjct: 125 ICKKSIDEAVAIIKPKVTTHAISNAIQKFIEKNGYFVLRDFAGHGCGN-EIHEDPLIPN- 182
Query: 170 YRP--HDNYKLREGDVFAIEPFATTGA 194
YR + N L E V IEP +G+
Sbjct: 183 YRSLLYRNVTLEENMVICIEPMILSGS 209
>sp|P57324|AMPM_BUCAI METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE M)
>gi|10038910|dbj|BAB12945.1| (AP001118) methionine
aminopeptidase [Buchnera sp. APS]
Length = 264
Score = 73.4 bits (177), Expect = 3e-12
Identities = 54/209 (25%), Positives = 100/209 (47%), Gaps = 17/209 (8%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIE--------LGAKPAFP-- 51
++ K+ +GK+A +V E + +P +S ++ + I+ LG FP
Sbjct: 10 EIKKMRISGKLAAEVLEMIKEHLQPKISTEDINQICHDYIVYKKKAISACLGYH-GFPKS 68
Query: 52 VNLSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVG---MEEDDLM 108
+ +S+N++ H P K KEGD + IDI + DGY DT+ +G + L
Sbjct: 69 ICISINDVVCHGIPSKNQ--VFKEGDIVNIDIAIIKDGYHGDTSKMFYIGKTSILSKRLC 126
Query: 109 EAAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPN 168
+ ARE+L ++ + + G+ + ++G I++ + F+ + GH I R H + +
Sbjct: 127 QVARESLYLSLKLVKPGIPLYKIGEIIQNYVESNNFSVVKEYCGHGIGR-NFHEEPHVLH 185
Query: 169 IYRPHDNYKLREGDVFAIEPFATTGAGQV 197
+N L++G +F IEP +G +V
Sbjct: 186 YKNKKNNIILKKGMIFTIEPMINSGNPEV 214
>pir||E82845 methionine aminopeptidase XF0111 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9104893|gb|AAF82924.1|AE003865_1
(AE003865) methionine aminopeptidase [Xylella
fastidiosa]
Length = 259
Score = 73.0 bits (176), Expect = 4e-12
Identities = 58/204 (28%), Positives = 92/204 (44%), Gaps = 15/204 (7%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIEL-GAKPA------FPVNL 54
+++++ AG++A V + KPGV+ EL + I+ + GA PA FP +
Sbjct: 11 EIEQMRIAGRLAATVLDVVAPYVKPGVTTAELDQICHDYIVTVQGAIPANLGYRGFPKTI 70
Query: 55 --SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVG---MEEDDLME 109
S+N + H P D LK+GD + ID+ V DG+ DT+ VG + L+E
Sbjct: 71 CTSVNNVICHGIP--SDAKVLKDGDIINIDVTVIKDGWHGDTSRMYYVGNPSVMARRLVE 128
Query: 110 AAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNI 169
EA+ I + G + ++G AI+ F+ + GH I + H + +
Sbjct: 129 TTYEAMWRGIRAVKPGATLGDIGHAIQIYAENERFSVVREYCGHGIGKV-YHDNPQVLHY 187
Query: 170 YRPHDNYKLREGDVFAIEPFATTG 193
RP + L G F IEP G
Sbjct: 188 GRPGEGLVLESGMTFTIEPMINEG 211
>pir||T35553 methionine aminopeptidase - Streptomyces coelicolor
>gi|2924293|emb|CAA58139.1| (X83011) methionine
aminopeptidase [Streptomyces coelicolor]
>gi|3449236|emb|CAA20380.1| (AL031317) methionine
aminopeptidase [Streptomyces coelicolor A3(2)]
Length = 278
Score = 71.4 bits (172), Expect = 1e-11
Identities = 63/219 (28%), Positives = 100/219 (44%), Gaps = 23/219 (10%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKP------AFPVNL-- 54
+ K+ EAG + + + A PG + +L + + E AKP FP +
Sbjct: 10 IAKMREAGLVVAAIHAATREAAVPGATTKDLDQVARKVLAEHDAKPNFLGYGGFPATICT 69
Query: 55 SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGM-EEDDLMEAAR- 112
S+NE+ H P D+ LK+GD + ID G IDG+ D A T VG +L+E +R
Sbjct: 70 SVNEVVVHGIP--SDDVVLKDGDVISIDCGAIIDGWHGDAAYTAFVGSGHSPELVELSRV 127
Query: 113 --EALESAISVARAGVEIKELGRAIEDEIRKR------GFNPIVNLSGHKIERYKLHAGI 164
E++ + I+ + G + ++ RAIE IR++ + I + GH I ++H
Sbjct: 128 TEESMWAGIAAMKQGNRLVDVSRAIETYIRRQPKPGGGKYGIIEDYGGHGIGT-EMHMDP 186
Query: 165 SIPNIY--RPHDNYKLREGDVFAIEPFATTGAGQVIEVP 201
+ N R KL G AIEP + G + +P
Sbjct: 187 HLLNYVDRRRGKGPKLVPGFCLAIEPMVSLGTPRTEVLP 225
>sp|O84859|AMPM_CHLTR METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE M)
>gi|7435565|pir||D71462 probable methionine
aminopeptidase - Chlamydia trachomatis (serotype D,
strain UW3/Cx) >gi|3329324|gb|AAC68448.1| (AE001358)
Methionine Aminopeptidase [Chlamydia trachomatis]
Length = 291
Score = 71.4 bits (172), Expect = 1e-11
Identities = 56/204 (27%), Positives = 97/204 (47%), Gaps = 18/204 (8%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLEL---AEKIEGRIIELGAK-----PAFPVNL 54
++K+ +A ++ + + + AK GV+ EL + ++ R + A P FP +
Sbjct: 49 IEKIRKACQVTAHILDALCEAAKEGVTTNELDLLSRELHKRHNAIPAPLNYGHPPFPKTI 108
Query: 55 --SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEED---DLME 109
SLNE+ H P ++ L+ GD + ID+ +DG+ D + V +G + + E
Sbjct: 109 CTSLNEVICHGIP---NDIPLQNGDIMNIDVSCIVDGFYGDCSRMVMIGEVSEIKRKVCE 165
Query: 110 AAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNI 169
A+ EAL +AIS+ + + E+G IE+ K GF+ + GH + K H + +
Sbjct: 166 ASLEALNAAISILEPNLPLYEIGEVIENCAAKYGFSVVDQFVGHGV-GVKFHENPFVAH- 223
Query: 170 YRPHDNYKLREGDVFAIEPFATTG 193
+R L G +F IEP G
Sbjct: 224 HRNSCKIPLAPGMIFTIEPMINVG 247
>pir||T40384 probable methionine aminopeptidase 1 - fission yeast
(Schizosaccharomyces pombe) >gi|3130036|emb|CAA19013.1|
(AL023534) putative methionine aminopeptidase
[Schizosaccharomyces pombe]
Length = 379
Score = 71.0 bits (171), Expect = 2e-11
Identities = 60/208 (28%), Positives = 94/208 (44%), Gaps = 21/208 (10%)
Query: 11 KIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKP------AFPVNL--SLNEIAAH 62
++ ++V + A +PG + EL + IE P AFP ++ S+NEI H
Sbjct: 133 RLGREVLDAAAAAVRPGTTTDELDSIVHNACIERDCFPSTLNYYAFPKSVCTSVNEIICH 192
Query: 63 YTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDD------LMEAAREALE 116
P D+ L++GD + ID+ ++ +G+ D T VG + L+E R AL+
Sbjct: 193 GIP---DQRPLEDGDIVNIDVSLYHNGFHGDLNETYYVGDKAKANPDLVCLVENTRIALD 249
Query: 117 SAISVARAGVEIKELGRAIE---DEIRKRGFNPIVNLSGHKIERYKLHAGISIPNIYRPH 173
AI+ + GV +E G IE + I ++ + + GH I + H SIP+
Sbjct: 250 KAIAAVKPGVLFQEFGNIIEKHTNSITEKQISVVRTYCGHGINQL-FHCSPSIPHYSHNK 308
Query: 174 DNYKLREGDVFAIEPFATTGAGQVIEVP 201
R G F IEP T G + I P
Sbjct: 309 APGIARPGMTFTIEPMLTLGPARDITWP 336
>pir||G81724 methionine aminopeptidase TC0240 [imported] - Chlamydia muridarum
(strain Nigg) >gi|7190280|gb|AAF39111.1| (AE002291)
methionine aminopeptidase [Chlamydia muridarum]
Length = 295
Score = 71.0 bits (171), Expect = 2e-11
Identities = 55/204 (26%), Positives = 96/204 (46%), Gaps = 18/204 (8%)
Query: 3 VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPA--------FPVNL 54
++K+ +A ++ ++ + K AK GV+ EL + + A PA FP +
Sbjct: 53 IEKIRKACQVTARILDALCKAAKEGVTTNELDQLSCNLHKQYNAIPAPLNYGQPPFPKTI 112
Query: 55 --SLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEED---DLME 109
SLNE+ H P ++T L+ GD + ID+ +DG+ D + V +G + + E
Sbjct: 113 CTSLNEVICHGIP---NDTPLQNGDIMNIDVSCIVDGFYGDCSRMVMIGEVPEIKKKVCE 169
Query: 110 AAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAGISIPNI 169
A+ EAL +AI++ + + E+G IE+ + GF+ + GH + + H + +
Sbjct: 170 ASLEALNAAIAILEPNLPLYEIGEVIENCAARYGFSVVDQFVGHGV-GVRFHENPYVAH- 227
Query: 170 YRPHDNYKLREGDVFAIEPFATTG 193
+R L G F IEP G
Sbjct: 228 HRNSCKIPLAPGMTFTIEPMINVG 251
>pir||C75134 x-pro aminopeptidase (pepq-3) PAB1781 - Pyrococcus abyssi (strain
Orsay) >gi|5458299|emb|CAB49788.1| (AJ248285) X-pro
aminopeptidase (pepQ-3) [Pyrococcus abyssi]
Length = 355
Score = 70.6 bits (170), Expect = 2e-11
Identities = 57/193 (29%), Positives = 90/193 (46%), Gaps = 14/193 (7%)
Query: 2 DVDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKPAFPVNLSLNEIAA 61
+++ + A +IA KV EE + G+S ELA KIE RI EL +F ++ E +A
Sbjct: 136 EIENMKHAARIADKVFEEILSWDILGMSEKELALKIEVRIRELSDGVSFSPIVASGENSA 195
Query: 62 --HYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEEDDLMEA---AREALE 116
H+ P E +++GD + +D G GY +D T+ VG ++ L+E +EA E
Sbjct: 196 NPHHEP---GERKIRKGDIVILDYGARWRGYCSDITRTIAVGRPDEKLIEVYEIVKEAQE 252
Query: 117 SAISVARAGVEIKELGRAIEDEIRKRGFNP-IVNLSGHKIERYKLHAGISIPNIYRPHDN 175
A R G++ KE+ + + I + G+ + +GH L + P
Sbjct: 253 KAYRAVREGIKAKEVDKVAREVISEAGYGEYFTHRTGH-----GLGLDVHEEPYIGPDGE 307
Query: 176 YKLREGDVFAIEP 188
L G F IEP
Sbjct: 308 VTLENGMTFTIEP 320
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.318 0.139 0.387
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 105311759
Number of Sequences: 2977
Number of extensions: 4411480
Number of successful extensions: 11273
Number of sequences better than 1.0e-10: 95
Number of HSP's better than 0.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 10959
Number of HSP's gapped (non-prelim): 125
length of query: 295
length of database: 189,106,746
effective HSP length: 57
effective length of query: 238
effective length of database: 154,992,987
effective search space: 36888330906
effective search space used: 36888330906
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 165 (68.7 bits)