BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1436 (moeA-1) DE:molybdenum cofactor biosynthesis protein
(moeA-1)
         (402 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||A75054 molybdenum cofactor biosynthesis protein (moea-1) PA...   786  0.0
pir||B71173 probable molybdopterin biosynthesis moea protein - P...   686  0.0
gi|11498536 molybdenum cofactor biosynthesis protein (moeA-1) [A...   374  e-102
pir||G69000 molybdenum cofactor biosynthesis protein MoeA - Meth...   342  5e-93
sp|Q58296|Y886_METJA PUTATIVE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN...   339  4e-92
gi|11498535 molybdenum cofactor biosynthesis protein (moeA-2) [A...   288  8e-77
pir||G71044 probable molybdopterin biosynthesis moeA protein - P...   282  6e-75
pir||C75170 molybdenum cofactor biosynthesis protein (moea-2) PA...   279  3e-74
gb|AAG18719.1| (AE004976) molybdenum cofactor biosynthesis prote...   266  4e-70
emb|CAC12151.1| (AL445066) molybdopterin biosynthesis protein (m...   261  1e-68
pir||A69049 molybdenum cofactor biosynthesis MoeA - Methanobacte...   255  6e-67
gi|11497778 molybdenum cofactor biosynthesis protein (moeA-3) [A...   241  1e-62
sp|Q58080|Y666_METJA PUTATIVE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN...   238  8e-62
dbj|BAA76925.1| (AB017192) molybdenum cofactor biosynthesis prot...   236  2e-61
gb|AAK42517.1| Molybdopterin biosynthesis protein (moeA-2) [Sulf...   235  6e-61
gb|AAG18720.1| (AE004977) molybdenum cofactor biosynthesis prote...   229  6e-59
emb|CAB59677.1| (AL132674) molybdopterin biosynthesis protein. [...   224  1e-57
pir||E70302 molybdenum cofactor biosynthesis protein A - Aquifex...   221  9e-57
pir||E82188 molybdopterin biosynthesis MoeA protein VC1527 [impo...   217  2e-55
dbj|BAB06740.1| (AP001517) molybdopterin biosynthesis [Bacillus ...   217  2e-55
sp|P12281|MOEA_ECOLI MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi...   215  5e-55
emb|CAC12152.1| (AL445066) molybdopterin biosynthesis protein (m...   210  2e-53
sp|Q39054|CNX1_ARATH MOLYBDOPTERIN BIOSYNTHESIS CNX1 PROTEIN (MO...   202  5e-51
sp|P45210|MOEA_HAEIN MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi...   200  2e-50
pir||C83266 molybdenum cofactor biosynthesis protein A2 PA3028 [...   200  2e-50
pir||E82439 molybdopterin biosynthesis MoeA protein VCA0617 [imp...   198  8e-50
dbj|BAA92623.1| (AB037806) KIAA1385 protein [Homo sapiens]            198  1e-49
gb|AAF81785.1|AF272663_1 (AF272663) gephyrin [Homo sapiens]           198  1e-49
gi|10880983 gephyrin; gephryin [Homo sapiens] >gi|10636475|emb|C...   198  1e-49
sp|Q03555|GEPH_RAT GEPHYRIN (PUTATIVE GLYCINE RECEPTOR-TUBULIN L...   198  1e-49
gi|11435181 gephyrin [Homo sapiens]                                   198  1e-49
pir||G70829 probable molybdenum cofactor biosynthesis protein - ...   196  4e-49
emb|CAA67416.1| (X98917) orf5 [Methanopyrus kandleri]                 195  7e-49
pir||E69659 molybdopterin biosynthesis protein moeA - Bacillus s...   192  4e-48
gb|AAC83139.1| (AF109295) MoeA [Staphylococcus carnosus]              191  1e-47
sp|Q44243|MOEA_ANASP MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi...   190  3e-47
sp|O05577|MOEA_MYCTU MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi...   187  1e-46
pir||T45454 probable molybdenum cofactor biosynthesis protein [i...   187  2e-46
sp|Q56066|MOEA_SALTY MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi...   185  6e-46
gb|AAD49748.1|AF174130_1 (AF174130) gephyrin [Gallus gallus]          183  4e-45
pir||B75562 molybdopterin biosynthesis MoeA - Deinococcus radiod...   181  1e-44
gb|AAF73075.1|AF268595_1 (AF268595) molybdenum cofactor biosynth...   180  2e-44
pir||H83155 molybdenum cofactor biosynthetic protein A1 PA3914 [...   179  6e-44
pir||T46858 molybdenum cofactor biosynthesis protein A [imported...   176  3e-43
pir||G71966 molybdopterin biosynthesis protein - Helicobacter py...   167  2e-40
pir||D64541 molybdopterin biosynthesis protein - Helicobacter py...   167  2e-40
pir||T44851 molybdopterin co-factor synthesis protein moeA [impo...   163  4e-39
gb|AAK40978.1| Molybdopterin biosynthesis protein (moeA-1) [Sulf...   162  5e-39
emb|CAB57627.1| (Y18930) molybdopterin biosynthesis protein [Sul...   162  5e-39
emb|CAA04211.1| (AJ000662) MoeA protein [Wolinella succinogenes]      160  3e-38
sp|Q56207|MOEA_SYNP7 MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi...   159  7e-38
pir||A81359 probable molybdopterin biosynthesis protein Cj0857c ...   156  5e-37
emb|CAB57390.1| (AJ238348) MoeA protein [Rhodobacter capsulatus]      151  2e-35
pir||B81299 probable molybdopterin biosynthesis protein Cj1519 [...   148  8e-35
emb|CAB65851.1| (AL050231) alternatively spliced form [Drosophil...   142  6e-33
emb|CAB65852.1| (AL050231) EG:BACR37P7.3 [Drosophila melanogaste...   142  6e-33
sp|P39205|CIN_DROME MOLYBDENUM COFACTOR SYNTHESIS PROTEIN CINNAM...   142  8e-33
sp|Q55368|MOEA_SYNY3 MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi...   142  8e-33
pir||T20638 hypothetical protein T06H11.4 - Caenorhabditis elega...   131  1e-29
pir||H72739 probable molybdopterin biosynthesis moeA protein APE...   126  5e-28
pir||F72773 probable molybdopterin biosynthesis protein APE0177 ...   100  3e-20
pir||T36508 probable molybdenum cofactor biosynthesis protein - ...    98  2e-19
pir||T42407 gephyrin homolog - Caenorhabditis elegans >gi|281122...    93  5e-18

>pir||A75054 molybdenum cofactor biosynthesis protein (moea-1) PAB1436 -
           Pyrococcus abyssi (strain Orsay)
           >gi|5458839|emb|CAB50326.1| (AJ248287) molybdenum
           cofactor biosynthesis protein (moeA-1) [Pyrococcus
           abyssi]
           Length = 402
           
 Score =  786 bits (2008), Expect = 0.0
 Identities = 402/402 (100%), Positives = 402/402 (100%)

Query: 1   MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60
           MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA
Sbjct: 1   MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60

Query: 61  VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120
           VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV
Sbjct: 61  VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120

Query: 121 ERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRK 180
           ERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRK
Sbjct: 121 ERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRK 180

Query: 181 PKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELI 240
           PKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELI
Sbjct: 181 PKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELI 240

Query: 241 EEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGL 300
           EEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGL
Sbjct: 241 EEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGL 300

Query: 301 PGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAV 360
           PGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAV
Sbjct: 301 PGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAV 360

Query: 361 PILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFEGW 402
           PILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFEGW
Sbjct: 361 PILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFEGW 402


>pir||B71173 probable molybdopterin biosynthesis moea protein - Pyrococcus
           horikoshii >gi|3256988|dbj|BAA29671.1| (AP000002) 402aa
           long hypothetical molybdopterin biosynthesis moea
           protein [Pyrococcus horikoshii]
           Length = 402
           
 Score =  686 bits (1751), Expect = 0.0
 Identities = 337/402 (83%), Positives = 370/402 (91%)

Query: 1   MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60
           MAFLKVVPLE+ALE+V SF +  G EEV + + LGRI AEDIYSPID+PPFDRATVDGYA
Sbjct: 1   MAFLKVVPLEKALEVVQSFKISPGIEEVPIEKGLGRIAAEDIYSPIDVPPFDRATVDGYA 60

Query: 61  VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120
           VRAEDTFMASEA+P++LKV+G +HAGEEPK +L KGE  YISTGAMLP NADAVIQFEDV
Sbjct: 61  VRAEDTFMASEASPVRLKVIGSVHAGEEPKFKLGKGEAAYISTGAMLPGNADAVIQFEDV 120

Query: 121 ERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRK 180
           ERV  EI+IYKPAYPGLGVMKKG+DI KGRLLV+KGERLGFKQTALLSAVG+ +V+VFRK
Sbjct: 121 ERVNGEILIYKPAYPGLGVMKKGIDIEKGRLLVKKGERLGFKQTALLSAVGINKVKVFRK 180

Query: 181 PKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELI 240
           PKVA+ISTGNEIV PG+ELKPGQIYDINGRAL DA+NELGGEGIF+G+ARDD+ESLK LI
Sbjct: 181 PKVAVISTGNEIVPPGNELKPGQIYDINGRALCDAINELGGEGIFMGVARDDKESLKALI 240

Query: 241 EEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGL 300
           E+ V V D+VVISGGASGG +DLTASVIEELGEVKVHGIAIQPGKPTIIG I GKPVFGL
Sbjct: 241 EKAVNVGDVVVISGGASGGTKDLTASVIEELGEVKVHGIAIQPGKPTIIGVIKGKPVFGL 300

Query: 301 PGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAV 360
           PGYPTSCLTNFTLLVVPLLLRALGREGK+ K  ARLKHK+FSVKGRRQFLPVKLEG +AV
Sbjct: 301 PGYPTSCLTNFTLLVVPLLLRALGREGKIGKKVARLKHKVFSVKGRRQFLPVKLEGDLAV 360

Query: 361 PILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFEGW 402
           PILKGSGAVTSFIDADGF+EIPETVES+DEGEEVEVTLF+GW
Sbjct: 361 PILKGSGAVTSFIDADGFVEIPETVESLDEGEEVEVTLFKGW 402


>gi|11498536 molybdenum cofactor biosynthesis protein (moeA-1) [Archaeoglobus
           fulgidus] >gi|7429678|pir||C69366 molybdenum cofactor
           biosynthesis protein (moeA-1) homolog - Archaeoglobus
           fulgidus >gi|2649665|gb|AAB90307.1| (AE001039)
           molybdenum cofactor biosynthesis protein (moeA-1)
           [Archaeoglobus fulgidus]
           Length = 654
           
 Score =  374 bits (950), Expect = e-102
 Identities = 197/405 (48%), Positives = 273/405 (66%), Gaps = 8/405 (1%)

Query: 3   FLKVVPLERALEIV-NSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAV 61
           F  VV ++ A  ++ N F+    TE V L  A GR++A+D+Y+  D+PPFDRAT+DGYAV
Sbjct: 5   FRDVVTVDEARGLLFNHFSPRRKTEVVPLHLAAGRVLAKDVYALTDVPPFDRATMDGYAV 64

Query: 62  RAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVE 121
           RAEDTF A E +P+ LKVVG + AG+ P+LE++ G+ V I+TGAM+PK A+AV+  E   
Sbjct: 65  RAEDTFEAEEDSPVTLKVVGTVEAGKRPELEVESGKAVEIATGAMMPKGANAVVMVEFTR 124

Query: 122 RVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKP 181
           R  DEI I+KP  PG  VM  G D+  G L+ R+G  L  ++  +++A G+  V V+ +P
Sbjct: 125 RREDEIDIFKPVSPGENVMYAGSDVMAGELIAREGTELTHREIGVMAACGISEVEVYCRP 184

Query: 182 KVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIE 241
           KVAIISTGNE+V PG  L  G+IYD+N  +++ AV E GGE I +GIARD+ E ++ +I 
Sbjct: 185 KVAIISTGNELVKPGERLGEGKIYDVNSYSIAAAVEENGGEAILMGIARDNEEEMRSIIA 244

Query: 242 EGVRVADIVVISGGASGGMRDLTASVIEELGE-VKVHGIAIQPGKPTIIGEINGKPVFGL 300
           + +R ADIV+ SG  S G  D+   ++++    V VHGIAI+PGKP +I   + KP+FGL
Sbjct: 245 KALREADIVITSGSTSAGAGDVMYRILDDFHPGVIVHGIAIKPGKPAVIAVSDSKPIFGL 304

Query: 301 PGYPTSCLTNFTLLVVPLLLRALG-REGKVRKVKARLKHKIFSVKGRRQFLPVKL----E 355
           PGYPTS +T F ++V P++    G RE    KV+ARL  K+FS +GRR++LPV +    E
Sbjct: 305 PGYPTSAMTVFEVIVAPIIRELAGRRESSGAKVRARLAIKVFSAEGRREYLPVNVVEGAE 364

Query: 356 GGVAVPILKG-SGAVTSFIDADGFIEIPETVESVDEGEEVEVTLF 399
           G  A P+    SGAVT+F   DGF+EIPE V  ++EG+EVEV LF
Sbjct: 365 GYSAYPVSGSYSGAVTAFAFTDGFVEIPENVVMLEEGDEVEVKLF 409


>pir||G69000 molybdenum cofactor biosynthesis protein MoeA - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622104|gb|AAB85499.1| (AE000873) molybdenum
           cofactor biosynthesis protein MoeA [Methanobacterium
           thermoautotrophicum]
           Length = 409
           
 Score =  342 bits (867), Expect = 5e-93
 Identities = 181/402 (45%), Positives = 250/402 (62%), Gaps = 4/402 (0%)

Query: 3   FLKVVPLERALEIVNSFTLPL---GTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGY 59
           FL+++ L+ A  I       L   GTE V + +A GR++A+DI SP+D+PPFDRA+ DGY
Sbjct: 6   FLEIIDLDDARRITGELFSELYSQGTESVDILDADGRVLADDIESPVDLPPFDRASRDGY 65

Query: 60  AVRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFED 119
           AVRA DTF A E NP  L+ +  + AG  P LE+ +G    ISTGA +P+ ADAV+  E 
Sbjct: 66  AVRAADTFGADEENPATLRCIETVEAGSVPSLEVAEGLCTRISTGAPVPEGADAVVMVEY 125

Query: 120 VERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFR 179
                D + I +PAYP   +  +G DI  G +L+R G  L   + A LSA G+ RV V  
Sbjct: 126 TWEEVDRVYIQRPAYPSQHIAARGSDIRAGNVLLRTGTVLSPDKIAALSAAGITRVNVIS 185

Query: 180 KPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKEL 239
           KP V +ISTGNE++ P  +L+PG+I+D N   LS A+ E G      GI RDD   L++ 
Sbjct: 186 KPSVCVISTGNELIEPSGQLEPGKIFDSNSAGLSSALKEAGCSVKHGGIVRDDYGELRDA 245

Query: 240 IEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFG 299
           I  G+  AD+V+ SGG S G  D+ + V++ELG V +HGI+I+PGKPTI+G ++ K V G
Sbjct: 246 ILRGLEEADMVITSGGTSAGAGDILSEVLDELGRVVIHGISIKPGKPTIVGVVDDKIVVG 305

Query: 300 LPGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKA-RLKHKIFSVKGRRQFLPVKLEGGV 358
           LPG+P S L  F  L+ P + +  GR+     VK  +L  ++ S +GR  +  V ++G  
Sbjct: 306 LPGFPVSALIVFMSLIEPFIRKLSGRKASSGHVKTLKLAERLHSSRGRVHYALVMVDGDY 365

Query: 359 AVPILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFE 400
           A PI K SGAV +   ADG+IE+P+ VE ++EGEEVEV LFE
Sbjct: 366 ARPIFKDSGAVAALAGADGYIEVPKNVEIINEGEEVEVVLFE 407


>sp|Q58296|Y886_METJA PUTATIVE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN MJ0886
           >gi|2129131|pir||F64410 molybdenum cofactor biosynthesis
           protein moeA homolog - Methanococcus jannaschii
           >gi|1591564|gb|AAB98890.1| (U67532) molybdenum cofactor
           biosynthesis protein (moeA) [Methanococcus jannaschii]
           Length = 620
           
 Score =  339 bits (860), Expect = 4e-92
 Identities = 192/404 (47%), Positives = 263/404 (64%), Gaps = 19/404 (4%)

Query: 3   FLKVVPLERALEIVNSFTLPLGTE--EVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60
           +L +  +E A  I+N     L  E  EV L  A+GR++AED++S IDIPP+DRA +DGYA
Sbjct: 4   YLTLHSIEEAKSIINESLKKLKNEVEEVDLFNAIGRVLAEDVFSNIDIPPYDRAKMDGYA 63

Query: 61  VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120
           V+AEDT+ A E NP++LKV+G + AGE   LE+  GE V I+TGA++PK A+AV+  E  
Sbjct: 64  VKAEDTYEADEDNPVELKVIGSLKAGEIKDLEINNGECVEIATGAIIPKGANAVVMVEYT 123

Query: 121 ERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRK 180
           ER  D + IY+   P   +   G DI  G L++RK  +L  +   +L+A+G  +V+V++K
Sbjct: 124 ERDNDRVKIYRAVPPMENIQFTGSDIMAGELVLRKNTKLTPRDIGVLAAIGKSKVKVYKK 183

Query: 181 PKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELI 240
            K  IISTGNEI+ P  +L+ G+IYDIN   L   +  LG +  F GIA+DD+E LKE I
Sbjct: 184 LKFGIISTGNEIISPNEQLEFGKIYDINSYTLVSYIKTLGYDFEFFGIAKDDKEELKEKI 243

Query: 241 EEGVRVADIVVISGGASGGMRDLTASVIEELG-EVKVHGIAIQPGKPTIIGEINGKPVFG 299
           ++ ++  DI+++SGG S G+ DLT + I+ELG ++ VHGI I+PGKPTIIG+I+ K + G
Sbjct: 244 KKALK-CDIILLSGGTSAGVGDLTETAIKELGGKILVHGIKIKPGKPTIIGKIDNKLIVG 302

Query: 300 LPGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKL----E 355
           LPGYPTSCLT F +L         G E  V  VKA+   +  S KGR ++LPV L     
Sbjct: 303 LPGYPTSCLTIFDVL--------FGDEKNV--VKAKFPVRYISAKGRVEYLPVILVKHKN 352

Query: 356 GGVAVPILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLF 399
           G  A PI KGSGA+TS  +ADG+I I E  E + E E+VEV LF
Sbjct: 353 GFSAYPITKGSGAITSLSEADGYIIIDENKE-ILENEDVEVHLF 395


>gi|11498535 molybdenum cofactor biosynthesis protein (moeA-2) [Archaeoglobus
           fulgidus] >gi|7429691|pir||B69366 molybdenum cofactor
           biosynthesis protein (moeA-2) homolog - Archaeoglobus
           fulgidus >gi|2649666|gb|AAB90308.1| (AE001039)
           molybdenum cofactor biosynthesis protein (moeA-2)
           [Archaeoglobus fulgidus]
           Length = 414
           
 Score =  288 bits (729), Expect = 8e-77
 Identities = 158/380 (41%), Positives = 231/380 (60%), Gaps = 5/380 (1%)

Query: 23  LGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGE 82
           L TE+V +    GR++AEDI +  D+P F+RA +DGYAV+AEDTF AS +NPI L++ G 
Sbjct: 27  LETEDVSVYNLQGRVLAEDIVAGFDVPKFNRAAMDGYAVKAEDTFGASVSNPIMLQLAGS 86

Query: 83  IHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAYPGLGVMKK 142
           +  GE PK+ ++ G  V I TGAM+P+  +AV+  E     G+ + + K   P   V + 
Sbjct: 87  VEIGEVPKVVVESGMAVRIMTGAMMPEGTNAVVMLEHTRLNGNFVEVLKSVTPMKNVSRV 146

Query: 143 GVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELKPG 202
           G DI+ G ++ RKGE L  +   +++++G+E VRV+RKP+VA+I+TGNE+   G  L+  
Sbjct: 147 GEDIAAGEVVFRKGEILQPQDAGVIASLGIESVRVYRKPRVAVITTGNELAEVGEPLEGA 206

Query: 203 QIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISGGASGGMRD 262
           +IY+ N   + +A+ E G E I LGIARDD E L+  +++ +   D  VI+GG S G +D
Sbjct: 207 KIYNSNNPMICNALLEFGFEAISLGIARDDEEELRNKLQKALEF-DAAVITGGTSVGAKD 265

Query: 263 LTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFTLLVVPLLLRA 322
           L   V+ E GE+  HG++++PG PT    + GKPVF LPG P + L  F    +P L R 
Sbjct: 266 LVPDVVGEFGEIVFHGVSMKPGMPTGAAVVEGKPVFMLPGSPAAALLGFYTFAIPALYRM 325

Query: 323 LGREGKVRK---VKARLKHKIFSVKGRRQFLPVKLEGGVAVPI-LKGSGAVTSFIDADGF 378
           +      RK    K  L+ +I S  G R  + V  E G   PI + GSG ++SF+ A+  
Sbjct: 326 MNVRIIARKWSRQKGVLQGRIPSEIGVRSNVRVLWEDGKVYPIRISGSGILSSFVRANAL 385

Query: 379 IEIPETVESVDEGEEVEVTL 398
           + +PE  E  +EGEEVEVTL
Sbjct: 386 LVVPEDKEGYEEGEEVEVTL 405


>pir||G71044 probable molybdopterin biosynthesis moeA protein - Pyrococcus
           horikoshii >gi|3258076|dbj|BAA30759.1| (AP000006) 396aa
           long hypothetical molybdopterin biosynthesis moeA
           protein [Pyrococcus horikoshii]
           Length = 396
           
 Score =  282 bits (713), Expect = 6e-75
 Identities = 166/403 (41%), Positives = 237/403 (58%), Gaps = 12/403 (2%)

Query: 1   MAFLKVVPLERALEIV-NSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGY 59
           M F K+VP   AL+++ +       TE+V L EA+GR++AEDI +  DIPPFDRA VDGY
Sbjct: 2   MEFKKLVPYREALKLLLDDINEIEDTEKVPLREAVGRVLAEDIVTEFDIPPFDRAAVDGY 61

Query: 60  AVRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFED 119
           A+RAEDTF A E NPI+L V+ E+ AG   K E+  G+ + + TG  +PK A+AVI  E 
Sbjct: 62  AIRAEDTFQAREYNPIELTVIEEVPAGNVAKEEVTTGKAIKVLTGTRIPKGANAVIMQEM 121

Query: 120 VERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFR 179
           V+R GD+I + +P  PG  +   G D+ KG +++RKG  L  +  A+L A+G+++V V  
Sbjct: 122 VKREGDKIYVLRPVAPGQNIAFTGEDVKKGEVVLRKGTILRPQDVAMLKALGIKKVPVKV 181

Query: 180 KPKVAIISTGNEIVLPGSE--LKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLK 237
           KPKV II TG+E++   SE   K G+I + N   L   V +  GE I  G+  DD   +K
Sbjct: 182 KPKVGIIITGSELIEEPSEEGFKEGKIVETNSIMLQGLVEKFFGEPILYGVLPDDESIIK 241

Query: 238 ELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPV 297
           E +E+     DIV+I+GG++ G +D     +  L     HG  I+PG+P   GE     V
Sbjct: 242 ETLEKAKNECDIVLITGGSAFGDKDYAHKFVNLL----FHGTTIKPGRPFGYGE----KV 293

Query: 298 FGLPGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGG 357
           F + GYP S    F L V   L + +G +    KVKA L+  I S  GR +F+ +  E G
Sbjct: 294 FIMSGYPVSVFAQFNLFVKHALAKMVGAQNYEVKVKAILQDDIPSQLGRYEFIKIYYENG 353

Query: 358 VAVPI-LKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLF 399
           +A  I  KGSG ++S + ++ ++EIPE  E    GEEV +TL+
Sbjct: 354 IARVIKKKGSGILSSLLASNAYLEIPEDSEGYRRGEEVWITLY 396


>pir||C75170 molybdenum cofactor biosynthesis protein (moea-2) PAB2014 -
           Pyrococcus abyssi (strain Orsay)
           >gi|5457952|emb|CAB49442.1| (AJ248284) molybdenum
           cofactor biosynthesis protein (moeA-2) [Pyrococcus
           abyssi]
           Length = 395
           
 Score =  279 bits (707), Expect = 3e-74
 Identities = 159/403 (39%), Positives = 241/403 (59%), Gaps = 12/403 (2%)

Query: 1   MAFLKVVPLERALEIV-NSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGY 59
           M F K++P   AL ++ N  T     E V L EAL R++A+DI S  D+PPFDR+ VDGY
Sbjct: 1   MEFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGY 60

Query: 60  AVRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFED 119
           AVRAEDTF A E +PI+LKV+ E+ AGE PK+++  G  + + TGA +P+ A+AVI  E 
Sbjct: 61  AVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM 120

Query: 120 VERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFR 179
           V+R G++I + +P  PG  V  KG D+ KG +++RKG  L  +  A+L A+G++ V V R
Sbjct: 121 VKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKR 180

Query: 180 KPKVAIISTGNEIVLPGSE--LKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLK 237
           KP+V II TG+E+V   SE   + G+I + N   L   V++  GE I  G+  D+ + ++
Sbjct: 181 KPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIR 240

Query: 238 ELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPV 297
           E I++  R  D+V+++GG++ G +D     ++ L     HG  I+PG+P   GE     V
Sbjct: 241 EAIKKAKRECDLVLVTGGSAFGDKDYAHRFVKLL----FHGTTIKPGRPIGYGE----RV 292

Query: 298 FGLPGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGG 357
           F + GYP +    F L V   L + +G      K++A L+  + S  GR +F+ V    G
Sbjct: 293 FIMSGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDG 352

Query: 358 VAVPI-LKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLF 399
            A  I  KGSG ++S ++++ ++E+PE  E    GEEV +TL+
Sbjct: 353 KAKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395


>gb|AAG18719.1| (AE004976) molybdenum cofactor biosynthesis protein; MoeA2
           [Halobacterium sp. NRC-1]
           Length = 571
           
 Score =  266 bits (672), Expect = 4e-70
 Identities = 150/354 (42%), Positives = 207/354 (58%), Gaps = 10/354 (2%)

Query: 56  VDGYAVRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVI 115
           +DGYAVRA DTF ASEA+P +L V G +HAGEEP +E+  G  V +STGA++P  ADAV+
Sbjct: 1   MDGYAVRAADTFGASEADPARLSVAGTVHAGEEPAVEVTAGRAVVVSTGAVMPPGADAVV 60

Query: 116 QFEDVERV--GDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVE 173
           + E       GD + +     PG  VM  G DI+ G   +  G +L  ++  +LSA+GV 
Sbjct: 61  KVEATTEADGGDAVDVRTSVAPGTAVMLAGADIAAGSRAIGPGTKLTAREIGVLSALGVG 120

Query: 174 RVRVFRKPKVAIISTGNEIVLPGSELKP--GQIYDINGRALSDAVNELGGEGIFLGIARD 231
            VRV   P V IISTG+E+V PG  L    GQI+D+N   ++ AV   GGE +    A D
Sbjct: 121 SVRVRGAPTVGIISTGDELVRPGDPLDSAAGQIHDVNSHTIAAAVEAAGGEPVVYPHAGD 180

Query: 232 DRESLKELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGE 291
           D   ++ L+ E     D+V+ SG  S    D+   V EE G++ +HG+A++PGKP ++GE
Sbjct: 181 DYAEMERLLVESAADCDLVLSSGSTSASAVDVIYRVAEERGDLLLHGVAVKPGKPMLVGE 240

Query: 292 INGKPVFGLPGYPTSCLTNFTLLVVPLLLRALGR-EGKVRKVKARLKHKIFSVKGRRQFL 350
           I G    GLPGYP S LT F + V P++  A GR + +   V   +  +  S +GRR+ L
Sbjct: 241 IEGTAYVGLPGYPVSALTIFRVFVAPVVREAAGRGQPEPTVVTGEMARQERSAEGRRRLL 300

Query: 351 PVKL-EGG----VAVPILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLF 399
           PV L E G    +  P+ KGSGA TS +DADG + +P     V  G+ V+V LF
Sbjct: 301 PVGLVEDGAGDRLVYPVDKGSGATTSLVDADGTVTVPADTAYVAAGDSVDVALF 354


>emb|CAC12151.1| (AL445066) molybdopterin biosynthesis protein (moeA-1) related
           protein [Thermoplasma acidophilum]
           Length = 626
           
 Score =  261 bits (660), Expect = 1e-68
 Identities = 145/371 (39%), Positives = 217/371 (58%), Gaps = 4/371 (1%)

Query: 27  EVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIHAG 86
           EV + EA+G   AEDI+S  D+PPFDR+ VDG+AV   D   A E  P+ L++ G I  G
Sbjct: 29  EVPIEEAVGLTAAEDIFSQYDVPPFDRSEVDGFAVDHADVDGAQEDAPVTLRIAGSISPG 88

Query: 87  EEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAYPGLGVMKKGVDI 146
           E   + +++G+ VYI+TG+++PK +DAV+  ED  + GD + IY+  YPG  V   G DI
Sbjct: 89  ETGNVTVERGKAVYIATGSVMPKGSDAVVMVEDTRQHGDYVDIYRSVYPGENVAFAGTDI 148

Query: 147 SKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELKPGQIYD 206
           S G ++ + G  L  ++ A L+A GV RVRVF + ++ I STGNEIV PG+ LK GQI+D
Sbjct: 149 SLGDIIAKAGTVLTPEKLATLAASGVARVRVFDRIRIGIFSTGNEIVRPGTNLKLGQIFD 208

Query: 207 INGRALSDAVNELGG-EGIFLGIARDDRESLKELIEEGVRVADIVVISGGASGGMRDLTA 265
           +NG      ++  GG   +FLG   D  + + ++I + +   DI++ SG  S G  D+  
Sbjct: 209 VNGYYFQTKLSSSGGVHAVFLGSVPDREDDMVKIIRDNLDSFDILMASGSTSAGFLDMLY 268

Query: 266 SVIEEL-GEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFTLLVVPLLLRAL- 323
            VIE++ G +  HGI ++PGKPT  G I  K   G+PG+P S       +V+P + +A+ 
Sbjct: 269 RVIEKVGGSILFHGINMRPGKPTFFGRIGEKLFIGMPGFPLSSAVILNYIVIPSIRKAIS 328

Query: 324 GREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAVPILKGSGAVTSFIDADGFIEIPE 383
           G   + R VK  +K     ++    +  +    G A PI+  SG+++    ADGFI IP 
Sbjct: 329 GDFERPRVVKVPVKIAPDHMQ-ETVYPAIITRNGYAFPIMGNSGSISRIRFADGFIAIPG 387

Query: 384 TVESVDEGEEV 394
            ++ VD G+ V
Sbjct: 388 DLKYVDPGDNV 398


>pir||A69049 molybdenum cofactor biosynthesis MoeA - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622477|gb|AAB85846.1| (AE000899) molybdenum
           cofactor biosynthesis MoeA [Methanobacterium
           thermoautotrophicum]
           Length = 404
           
 Score =  255 bits (645), Expect = 6e-67
 Identities = 146/404 (36%), Positives = 228/404 (56%), Gaps = 8/404 (1%)

Query: 1   MAFLKVVPLERALEIVNS---FTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVD 57
           M   +++P+  A  I++    FT P   E V L EA  R++A+DI S  D PPFDR+ +D
Sbjct: 1   MFLSELLPVRDAFRILDENQRFTEP---ETVDLLEAYHRVLADDIVSRFDSPPFDRSAMD 57

Query: 58  GYAVRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQF 117
           GYAVRAEDTF +S  NP  L+V   I AGE   +++  GE V I+TGA +P  ADAV+  
Sbjct: 58  GYAVRAEDTFGSSPGNPSTLRVTDSIGAGEVSGVDVGHGEAVRIATGAPIPAGADAVVME 117

Query: 118 EDVERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRV 177
           E   + G +I + +P  P   V   G D+ +G  ++R+G  +  ++ A+ ++ G  +VRV
Sbjct: 118 EYTLQDGPDIRVLRPVAPSENVAPAGEDVRRGVTVLREGTLMRPQEIAMAASAGYSKVRV 177

Query: 178 FRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLK 237
           FR+P V +I TGNE+V P  +L+PG++ + N   L+  V   GG    + +  DD +++ 
Sbjct: 178 FRRPSVKVIVTGNELVDPSDDLEPGKVPNSNLYTLNALVESAGGSADPVHLP-DDIDTVG 236

Query: 238 ELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPV 297
           E IE      D+++ +GG +    D+    ++ LGEV  HG+A++PGKP   G ++  PV
Sbjct: 237 EEIESSASEYDVIITTGGTAISRGDVVVDAVDGLGEVLFHGVALRPGKPVAFGMVSETPV 296

Query: 298 FGLPGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGG 357
           F L GYP + +  F +     LLR    + + R VK R + K+ S  GR  +L    +  
Sbjct: 297 FMLSGYPVAAMVQFDVFARYYLLRMQHLDYRHRAVKRRCRAKVASGPGRTDYLRAWADDE 356

Query: 358 VAVPI-LKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFE 400
              P+  +GSG + S + ++ +I I E +E +  GEE +V LF+
Sbjct: 357 EVEPVQSRGSGIIRSMVGSNAYIVIDENLEGISAGEECDVLLFD 400


>gi|11497778 molybdenum cofactor biosynthesis protein (moeA-3) [Archaeoglobus
           fulgidus] >gi|7445252|pir||A69270 molybdenum cofactor
           biosynthesis protein (moeA-3) homolog - Archaeoglobus
           fulgidus >gi|2650482|gb|AAB91068.1| (AE001095)
           molybdenum cofactor biosynthesis protein (moeA-3)
           [Archaeoglobus fulgidus]
           Length = 400
           
 Score =  241 bits (609), Expect = 1e-62
 Identities = 151/404 (37%), Positives = 224/404 (55%), Gaps = 39/404 (9%)

Query: 14  EIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEAN 73
           E+   F     +EEV++ +AL R +AED+++  D+PPFD AT+DGYA++ ED        
Sbjct: 19  ELRQRFYFKRESEEVRVEDALDRELAEDVFAAKDMPPFDIATMDGYALKLEDGVR----- 73

Query: 74  PIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPA 133
             + ++VGE++AGE     + +GE VYI+TGA +P NAD V++ E  E  G ++ I +  
Sbjct: 74  --EYRIVGEVYAGEVEDRFVNRGECVYITTGAKMPVNADTVVKVEIAEVDGSKMRIREKV 131

Query: 134 YPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIV 193
             G  V+KKG ++ KG L++    R+G ++ A L + GVERVRVFR+ + A+ S G+EI 
Sbjct: 132 NRGKYVLKKGSEVKKGDLILPAKTRIGPQEIAALISAGVERVRVFRRLRAAVFSNGDEI- 190

Query: 194 LPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVIS 253
                 K G I D N   +S  + +LG E  FLG+A DD E ++E++E+GVR  D V+ S
Sbjct: 191 ------KKGIIADSNSAMISAFLRKLGCEVHFLGVAGDDAEEVREMVEKGVRDYDAVLTS 244

Query: 254 GGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFTL 313
           GG S G +D     ++E+GEV ++ +  +PGKP ++  +N KPVF LPG P  C T    
Sbjct: 245 GGVSVGEKDYVVKALKEMGEVLIYKVRQRPGKPMVVAVVNEKPVFALPGKPAGCFT---- 300

Query: 314 LVVPLLLRALGREGKVRKVKARLKHKI-FSVKGRRQFLPVKLEGGVAVP---------IL 363
             +  L R    +    KV+AR+   +    KG   FL VKL  G A+P         I+
Sbjct: 301 -AMLSLRRFFAGDKPFPKVRARIAGDVKLPTKGFSYFLFVKLRDGYAIPAGFRHSHVSII 359

Query: 364 KGSGAVTSFIDA-------DGFIEIPETVESVDEGEEVEVTLFE 400
                  S + A       DGF+    T   +  GEEVEV L++
Sbjct: 360 PYEKYEVSLVSAMARSAVSDGFV---VTDRDLRAGEEVEVCLYD 400


>sp|Q58080|Y666_METJA PUTATIVE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN MJ0666
           >gi|2129130|pir||B64383 molybdenum cofactor biosynthesis
           protein moeA homolog - Methanococcus jannaschii
           >gi|1591380|gb|AAB98661.1| (U67514) molybdenum cofactor
           biosynthesis protein (moeA) [Methanococcus jannaschii]
           Length = 398
           
 Score =  238 bits (601), Expect = 8e-62
 Identities = 148/384 (38%), Positives = 217/384 (55%), Gaps = 26/384 (6%)

Query: 26  EEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIHA 85
           +EV + EAL RI AEDI +PID+P F++A +DGYAV AEDTF ASE NPI L +      
Sbjct: 32  KEVDIVEALNRISAEDIKAPIDLPYFNKAAMDGYAVIAEDTFGASETNPIILNLAD---- 87

Query: 86  GEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAYPGLGVMKKGVD 145
           G+E    +  GE   I TG  LPKNA+AV+  E    V D + +YK  +P   V + G D
Sbjct: 88  GDE----ITYGEAKKIFTGDKLPKNANAVVMKEFCNEVDDFVEVYKTVHPNENVSRIGED 143

Query: 146 ISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELKP---- 201
           + KG ++++KGE +      +L+++G+++++V+      IISTG+E++    E++     
Sbjct: 144 VKKGDVVLKKGEIINPYHLNMLASLGIKKIKVYDL-SFGIISTGDELINL-DEIRDIEED 201

Query: 202 -----GQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISGGA 256
                G+I + N   L   V  LG       I +DD+E LK+ I+  +   D ++I+GG 
Sbjct: 202 ISKLDGKIINSNSYMLYGLVKNLGFNAKIYDIVKDDKEKLKKAIKTALSENDALLITGGT 261

Query: 257 SGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFTLLVV 316
           S   RD+T   + ELG+V VHG+ I+PGKP   G IN KPVF L GYP +    F L + 
Sbjct: 262 SVSERDITVETVRELGDVIVHGVNIRPGKPFGFGIINDKPVFMLSGYPVASAVQFELFIQ 321

Query: 317 PLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAVPILKGSGAVTSFIDAD 376
              +         +KV   LK  + S  GR  F+ VK++  V    + GSG ++S I +D
Sbjct: 322 RFFIER-------KKVTLPLKRNMASELGRVDFVRVKVDIEVEPIRITGSGVISSLIKSD 374

Query: 377 GFIEIPETVESVDEGEEVEVTLFE 400
           G+I IPE VE  ++GE V+V L +
Sbjct: 375 GYILIPENVEGYEKGELVDVYLLK 398


>dbj|BAA76925.1| (AB017192) molybdenum cofactor biosynthesis protein [Clostridium
           perfringens]
           Length = 406
           
 Score =  236 bits (597), Expect = 2e-61
 Identities = 146/401 (36%), Positives = 226/401 (55%), Gaps = 9/401 (2%)

Query: 5   KVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAE 64
           K + LE ALEI+N  T  L +E V + ++L R++  D+ S I+ PPF+++  DGYA ++E
Sbjct: 3   KFIALEEALEILNKNTKALKSEVVSIKDSLKRVLYGDVKSKINNPPFNKSVFDGYAFKSE 62

Query: 65  DTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVG 124
           D+   S+ NPI+LK+V EI AG+  ++E+K GE + I TGA +P  AD V++ E+ ER G
Sbjct: 63  DSKGTSKENPIELKIVDEIFAGDFSEIEIKHGEAIRIMTGAPIPVGADCVLKQEETERHG 122

Query: 125 DEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVA 184
           D + I+K       +   G DI  G  L++KG+RL +    ++++ G+  V V++KPKV+
Sbjct: 123 DLVKIFKEMKANENISFMGEDIKIGETLIKKGKRLDYADLGIMASSGISEVLVYKKPKVS 182

Query: 185 IISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGV 244
           IISTG+E+    S LKPG+IYD N  +LS  + ELG   + +    D+   + E IE+  
Sbjct: 183 IISTGDEVCDINSTLKPGKIYDSNLYSLSARIEELGYNVLSMEHVGDNILKIGEAIEKAF 242

Query: 245 RVADIVVISGGASGGMRDLTASVIEELG-EVKVHGIAIQPGKPTIIGEINGKPVFGLPGY 303
             +DIV  +GGAS G +DL   V   +G E     I I+PG   +  +   K +  L G 
Sbjct: 243 EKSDIVFTTGGASVGEKDLMQKVSGSIGFERLFWKIKIKPGSAVVCSKRQEKILISLSGN 302

Query: 304 PTSCLTNFTLLVVPLLLRALGREG--KVRKVKARLKHKIFSVKGRRQFLPVKL---EGGV 358
           P + LT F LL  P+L +  G E    +++ K  L         +R+FL   +   E G 
Sbjct: 303 PNAALTTFELLGKPVLKKLEGEEENINIKREKGVLMDSFNKKSPQRRFLRGNIIYDEKGA 362

Query: 359 AV---PILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEV 396
            V    I  G+G ++S ++A+  IEI +  E ++ GE V +
Sbjct: 363 KVYITQIKSGNGILSSLLNANCLIEIEKGNEGLNRGEVVNI 403


>gb|AAK42517.1| Molybdopterin biosynthesis protein (moeA-2) [Sulfolobus
           solfataricus]
           Length = 550
           
 Score =  235 bits (594), Expect = 6e-61
 Identities = 145/401 (36%), Positives = 234/401 (58%), Gaps = 21/401 (5%)

Query: 9   LERALEI-VNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTF 67
           +E A+ + ++S      T EV++ ++ G + AED+ SPID PPF R+ VDGYA++     
Sbjct: 17  IEEAIRVYLSSLNFIPKTVEVEVKDSFGYVSAEDLNSPIDYPPFSRSNVDGYALK----- 71

Query: 68  MASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEI 127
             S   P +LKV+  I  GE  ++ + +   V + TGA++P  ADAVI+ EDV+ +   +
Sbjct: 72  --SSCTPGELKVIDRIEIGEFKEVHINECVAVEVDTGAIIPMGADAVIKVEDVKIISGNL 129

Query: 128 I-IYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAII 186
           I + K    G  +   G DI K  +++RKGE +  ++  LL+++G+ +V+V+ K KV +I
Sbjct: 130 IKVDKKMTFGQNIGWIGSDIPKNSIILRKGEVISHEKIGLLASLGISKVKVYEKLKVYLI 189

Query: 187 STGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRV 246
           +TG+E+V PG+ L PG+IY+ N   L   + +   + + L + RDD ES+K  I+  + +
Sbjct: 190 ATGDELVEPGNSLSPGKIYESNLHYLYSKLKQ-NYQIVGLSLLRDDIESIKNEIKRAISL 248

Query: 247 ADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTS 306
           AD+++++GG S G +D     I+ELG + VHGI I+PGKPTI+G ++ KPV GLPG   S
Sbjct: 249 ADVLILTGGTSAGEKDFVHRAIKELGSIIVHGIKIKPGKPTILGVVDNKPVIGLPGNIVS 308

Query: 307 CLTNFTLLVVPLLLRALGREGK----VRKVKARLKHKIFSVKGRRQFLPVKLEGGV---- 358
            +  F   V+  +LR L    K    + K+KA+L     + K R   +PV L   V    
Sbjct: 309 SVVVFD-TVISEILRNLYPSRKEIVELGKIKAKLALGTKADKYRNTLIPVYLFKSVDSSY 367

Query: 359 -AVPILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTL 398
            A+P+   S  + +F   +G+I +    E ++EG+EVEV +
Sbjct: 368 YALPVKFESYMIGTFSLTEGYIMLNPN-EEIEEGKEVEVNV 407


>gb|AAG18720.1| (AE004977) molybdenum cofactor biosynthesis protein; MoeA1
           [Halobacterium sp. NRC-1]
           Length = 407
           
 Score =  229 bits (577), Expect = 6e-59
 Identities = 148/400 (37%), Positives = 209/400 (52%), Gaps = 25/400 (6%)

Query: 10  ERALEIVNSFTLPLG-TEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFM 68
           ER L  V+    PL  T  V L +A GR++A D+ +P  +P ++RA +DG+AVRA DTF 
Sbjct: 21  ERLLSAVD----PLARTARVALGDADGRVLAADVEAPRAVPHYERAAMDGFAVRAADTFG 76

Query: 69  ASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEII 128
           A + +P+ L V G    G         GE V + TG+ LP  ADAV+  ED ER GD + 
Sbjct: 77  AGDRSPVVLDV-GTGSVGP--------GEAVRVHTGSELPAGADAVVMIEDAERRGDRVD 127

Query: 129 IYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIIST 188
           ++  A  G  V   G D+S G+ L   G RL      LL + GV+ V V+ +P V ++ T
Sbjct: 128 VFAAAAGGANVAPIGEDVSDGQHLYDAGHRLRPSDLGLLKSAGVDAVAVYERPTVGVLPT 187

Query: 189 GNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVAD 248
           G E+V   ++  PG++ + NG  ++  V+  GG     G+  DD  +L+  I E V   D
Sbjct: 188 GEELV--AADPGPGEVVETNGGTVAQYVSRWGGVPTRRGVVTDDEAALRTAIREAVDSHD 245

Query: 249 IVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCL 308
           +VV +GG+S G RD    VI +LG V VHG+A+QPG P  +  ++  PV  LPGYP + +
Sbjct: 246 VVVTTGGSSVGARDHVPEVIADLGTVLVHGVALQPGHPVALCVVDDTPVVALPGYPVAAI 305

Query: 309 TNFTLLVVPLLLRALGREGKVR--KVKARLKHKIFSVKGRRQFLPVKLEGG------VAV 360
            N    + P LL+A+G           A L  KI S  G R F+ V   G       V  
Sbjct: 306 VNAVQFLRP-LLKAVGHAPATAHPTTDAVLARKIASEPGTRSFVRVTRHGDEDGRPTVTP 364

Query: 361 PILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFE 400
               GSG ++S   ADG++ +PE  E  D G  V V  +E
Sbjct: 365 TRAGGSGVLSSVALADGWVVVPEDCEGYDAGTTVAVEQWE 404


>emb|CAB59677.1| (AL132674) molybdopterin biosynthesis protein. [Streptomyces
           coelicolor A3(2)]
           Length = 424
           
 Score =  224 bits (565), Expect = 1e-57
 Identities = 149/418 (35%), Positives = 213/418 (50%), Gaps = 32/418 (7%)

Query: 13  LEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEA 72
           L+ V +   PL   E+ L +A G ++ +DI  P+ +PPFD +++DGYAVR  D   ASE 
Sbjct: 5   LDDVLATVRPLDPIELNLLDAQGCVLVDDITVPLSLPPFDNSSMDGYAVRVTDVAGASEE 64

Query: 73  NPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDE------ 126
            P  L+VVG++ AG+   + +  G+   I TGA LP  A+AV+  E  +    E      
Sbjct: 65  FPAVLEVVGDVAAGQTDPIAVGPGQAARIMTGAPLPPGAEAVVPVEWTDGGSGEGPVAGM 124

Query: 127 -------------IIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVE 173
                        + +Y+PA     V  KG D+  G   +  G  LG  Q  LL+A+G  
Sbjct: 125 RARSLAPEGAEGHVQVYRPAEERAHVRAKGSDVRSGDRALAAGTVLGPPQIGLLAAIGRG 184

Query: 174 RVRVFRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDR 233
            VRV  +P+V ++STG+E+V P  +L PGQIYD N  AL+ A  + G     +G   DD 
Sbjct: 185 TVRVRPRPRVVVLSTGSELVQPDEQLAPGQIYDSNSFALTAAARDAGAIAYRVGAVADDA 244

Query: 234 ESLKELIEEGVRVADIVVISGGASGGMRDLTASVIEELGE-------VKVHGIAIQPGKP 286
           E+L+  IE+ +  AD++V +GG S G  D+    +  +G+       V    +A+QPGKP
Sbjct: 245 ETLRATIEDQLVRADLMVTTGGVSVGAYDVVKEALAHVGDEDEPGGGVDFRKLAMQPGKP 304

Query: 287 TIIGEI--NGKPVFGLPGYPTSCLTNFTLLVVPLLLRALGREGKVR-KVKARL--KHKIF 341
              G +  +  P+  LPG P S   +F L V P +   +G     R  V A L     + 
Sbjct: 305 QGFGSVGPDHTPLLALPGNPVSSYVSFELFVRPAIRTLMGLPDVHRPTVTASLAADKALT 364

Query: 342 SVKGRRQFLPVKLEGGVAVPI-LKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTL 398
           S KGRRQFL     GG   P+   GS  V +   A+  I +PE  ESV+ G EVEV L
Sbjct: 365 SPKGRRQFLRGSHAGGSVTPVGGSGSHLVAALAQANALIVVPEDTESVEPGTEVEVVL 422


>pir||E70302 molybdenum cofactor biosynthesis protein A - Aquifex aeolicus
           >gi|2982782|gb|AAC06407.1| (AE000670) molybdenum
           cofactor biosynthesis protein A [Aquifex aeolicus]
           Length = 402
           
 Score =  221 bits (558), Expect = 9e-57
 Identities = 152/404 (37%), Positives = 223/404 (54%), Gaps = 15/404 (3%)

Query: 6   VVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAED 65
           + PLE AL+IV     PL +E V + EALGR++AED+ S  D P FD + +DGYAVR ED
Sbjct: 4   LTPLEEALKIVLENVKPLESERVFIHEALGRVLAEDVVSDTDKPLFDNSAMDGYAVRWED 63

Query: 66  TFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGD 125
                +  P KLKV+GE  AG    L+++KG  V I TGA +P+ AD V+  E  E    
Sbjct: 64  I----KEVPAKLKVIGEYAAGTGENLKVEKGTAVKIFTGAPIPEGADTVVPVEYTETQDG 119

Query: 126 EIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAI 185
            +I+ K    G  V ++G D+ KG +++ KG+ +   +  +L++V    V V+RKP V I
Sbjct: 120 YVIVKKSFKQGANVRRRGEDVKKGEVVIPKGKEIRPYEMGMLASVNRAVVSVYRKPHVGI 179

Query: 186 ISTGNEIV-LPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGV 244
           +STG+EI+ +   + KP QI   N   +   V + GG    LGIA D+ + LKE++   +
Sbjct: 180 LSTGDEILDVCEEQTKPSQIRTSNNYTVYGQVLQAGGIPHNLGIAPDEPQKLKEIM-RSI 238

Query: 245 RVADIVVISGGASGGMRDLTASVIEELG-EVKVHGIAIQPGKPTIIGEI-NGKPVFGLPG 302
              DI + +GG S G +D    ++E+LG +VK H + I+P KP + G     K  FGLPG
Sbjct: 239 HKYDIFITTGGVSMGEKDYVQYLVEDLGIDVKFHKLRIKPAKPVLFGVYGENKLFFGLPG 298

Query: 303 YPTSCLTNFTLLVVPLLLRALG-REGKVRKVKARLKHKIFSVKG-RRQFLPVKL--EGG- 357
            P S    F LLV P +    G RE   +KV A L+         RR+F   ++  E G 
Sbjct: 299 NPVSAAVAFDLLVYPAIKAMQGHREVFKQKVTAILEGDYRRKNADRREFARCRVWFENGR 358

Query: 358 -VAVPILK-GSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLF 399
               P  K  S  +TS ++++ ++ + E V  + +G+EVEV LF
Sbjct: 359 YHCEPYPKQDSHMLTSLVNSNAYMVVYEGVNELKKGQEVEVILF 402


>pir||E82188 molybdopterin biosynthesis MoeA protein VC1527 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9656032|gb|AAF94681.1| (AE004231) molybdopterin
           biosynthesis MoeA protein [Vibrio cholerae]
           Length = 606
           
 Score =  217 bits (547), Expect = 2e-55
 Identities = 136/410 (33%), Positives = 222/410 (53%), Gaps = 20/410 (4%)

Query: 2   AFLKVVPLERALEIVNSFTLPLG-TEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60
           AFL V   E+  E + S   PL  TE V + E   R++A +++SP ++P +  + +DGYA
Sbjct: 205 AFLSV---EQGREKILSLISPLAETESVAIQECYQRVLAREVFSPNNVPAYRNSAMDGYA 261

Query: 61  VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120
           +R++D    S       +VV E+ AG      +++GE V I TGA +P  AD V+  E  
Sbjct: 262 LRSDDLERDS------YRVVAEVLAGSHYPKTVERGEAVKIMTGAPMPLGADTVVMREQA 315

Query: 121 ERVGDEIIIYKPAY--PGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVF 178
            + G E++ +  A    G  V + G D+++G+ +   G+R+   +  +L+++G      F
Sbjct: 316 TQNG-ELVSFAGAKIKAGQNVRQAGEDLAQGQAVFSIGQRVLSPEMGMLASLGFAHADAF 374

Query: 179 RKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKE 238
           R  KVAI STG+E+  PG +++P  I+D N   L+  + +LG + I LGI  DD   + +
Sbjct: 375 RSLKVAIFSTGDEVQAPGGDIEPNSIFDSNRFTLTGLLKQLGCQVIDLGIIEDDEAKMMQ 434

Query: 239 LIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVF 298
           ++E+  + AD+V+ SGG S G  D   S +E+LG++    I ++PG+P   G+I GKP F
Sbjct: 435 VLEQAAKQADVVITSGGVSVGDADFIKSALEKLGQIDFWRINMRPGRPLAFGQIAGKPFF 494

Query: 299 GLPGYPTSCLTNFTLLVVPLLLRALGREG-KVRKVKARLKHKIFSVKGRRQF----LPVK 353
           GLPG P + + +F   V P L +  G +G +  KV A     + S +GR +F        
Sbjct: 495 GLPGNPVAVMVSFINFVEPALRKMQGEQGWQPLKVNAIALEDLRSRQGRTEFSRGVYAFN 554

Query: 354 LEGGVAVPIL--KGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFEG 401
            +G + V     +GSG + S  +A+  IEI   +++V  GE V +   +G
Sbjct: 555 TQGQLTVRTTGKQGSGILRSMSEANCLIEIAPAIDTVKVGESVTIIPLQG 604


>dbj|BAB06740.1| (AP001517) molybdopterin biosynthesis [Bacillus halodurans]
           Length = 423
           
 Score =  217 bits (546), Expect = 2e-55
 Identities = 132/406 (32%), Positives = 220/406 (53%), Gaps = 11/406 (2%)

Query: 7   VPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDT 66
           +P+  A+E V +F      E V L EA GR +A+ + +  ++PPFD++ +DG+A+RA DT
Sbjct: 8   IPVHEAVEQVVAFAKERAMEWVPLEEADGRFLAQPLVADHNVPPFDKSPLDGFAIRAVDT 67

Query: 67  FMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFE---DVERV 123
             A+   P++LK++ EI AG+  +    +GE + I TGA +P+  DAV+ FE   ++   
Sbjct: 68  EDATRETPVRLKIIEEIGAGQVAQKVPSQGEAIRIMTGAQMPEGTDAVVMFELTKEISEA 127

Query: 124 GDEIIIYKPAY-PGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPK 182
           G+  I  K ++ PG  +   G D  +G  LV KG ++     ALL+  G  +V V++ PK
Sbjct: 128 GESFIEVKRSFQPGDNISFCGEDAKEGTPLVEKGRQIDAGIKALLATFGYAKVPVYKMPK 187

Query: 183 VAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEE 242
           + I +TG E++     L PG+I + N   ++  V ++G E ++LG   DD +   + I  
Sbjct: 188 IGIFATGTELLEVDEPLVPGKIRNSNAYMVASQVKQIGAEPVYLGKLVDDFDQCYDAIAT 247

Query: 243 GVRVADIVVISGGASGGMRDLTASVIEELG-EVKVHGIAIQPGKPTIIGEINGKPVFGLP 301
            +   D++V +GG S G  D   ++ E+LG  V  + IA++PG  T + E  G+ +FGL 
Sbjct: 248 ALADVDVLVTTGGVSVGDYDYLPAIYEKLGANVLFNKIAMRPGSVTTVAEREGQLLFGLS 307

Query: 302 GYPTSCLTNFTLLVVPLL-LRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAV 360
           G P++C   F LLV P + +     +  +++VKA L           +F+  ++E  +  
Sbjct: 308 GNPSACFVGFELLVRPFIHVGFCSEQPFLKRVKATLGRDFPKPNPFTRFVRSQVEFKIDR 367

Query: 361 PILK-----GSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFEG 401
            I+K      SG VTS  +A+G + +P        G+EV+V L +G
Sbjct: 368 LIVKPTGLDKSGVVTSLANANGLLMLPGGTRGFQAGDEVDVLLLKG 413


>sp|P12281|MOEA_ECOLI MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|78705|pir||A32352
           molybdopterin biosynthesis protein moeA - Escherichia
           coli >gi|145539|gb|AAA23579.1| (M21151) chlE protein
           [Escherichia coli] >gi|1651376|dbj|BAA35515.1| (D90720)
           Molybdopterin biosynthesis MoeA protein. [Escherichia
           coli] >gi|1651379|dbj|BAA35522.1| (D90721) Molybdopterin
           biosynthesis MoeA protein. [Escherichia coli]
           >gi|1787049|gb|AAC73914.1| (AE000185) molybdopterin
           biosynthesis [Escherichia coli K12]
           Length = 411
           
 Score =  215 bits (543), Expect = 5e-55
 Identities = 142/403 (35%), Positives = 212/403 (52%), Gaps = 14/403 (3%)

Query: 6   VVPLERALEIVNSFTLPLGTEE-VKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAE 64
           ++ L+ AL  + S   PL  +E + L +  GRI+A D+ SP+D+P FD + +DGYAVR  
Sbjct: 7   LMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDVVSPLDVPGFDNSAMDGYAVRLA 66

Query: 65  DTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVG 124
           D      A+   L V G+  AG+    E   G  + I TGA +P+  +AV+  E  E++ 
Sbjct: 67  DI-----ASGQPLPVAGKSFAGQPYHGEWPAGTCIRIMTGAPVPEGCEAVVMQEQTEQMD 121

Query: 125 DEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVA 184
           + +        G  + ++G DIS G ++   G RL   +  +++++G+  V V RK +VA
Sbjct: 122 NGVRFTAEVRSGQNIRRRGEDISAGAVVFPAGTRLTTAELPVIASLGIAEVPVIRKVRVA 181

Query: 185 IISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGV 244
           + STG+E+ LPG  L  GQIYD N  A+   + +LG E I LGI RDD  +L+    E  
Sbjct: 182 LFSTGDELQLPGQPLGDGQIYDTNRLAVHLMLEQLGCEVINLGIIRDDPHALRAAFIEAD 241

Query: 245 RVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYP 304
             AD+V+ SGG S G  D T +++EELGE+    +AI+PGKP   G+++     GLPG P
Sbjct: 242 SQADVVISSGGVSVGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSWFCGLPGNP 301

Query: 305 TSCLTNFTLLVVPLLLRALGR--EGKVRKVKARLKHKIFSVKGRRQF----LPVKLEGGV 358
            S    F  LV PLL +  G    G   + + R   ++    GR  F    L    +G +
Sbjct: 302 VSATLTFYQLVQPLLAKLSGNTASGLPARQRVRTASRLKKTPGRLDFQRGVLQRNADGEL 361

Query: 359 AVPIL--KGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLF 399
            V     +GS   +SF   + FI +     +V+ GE VEV  F
Sbjct: 362 EVTTTGHQGSHIFSSFSLGNCFIVLERDRGNVEVGEWVEVEPF 404


>emb|CAC12152.1| (AL445066) molybdopterin biosynthesis protein (moeA-2) related
           protein [Thermoplasma acidophilum]
           Length = 399
           
 Score =  210 bits (529), Expect = 2e-53
 Identities = 119/402 (29%), Positives = 215/402 (52%), Gaps = 16/402 (3%)

Query: 1   MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60
           M F  + P   A+ + +   + +    V ++E++GR  + D+ SP+D P  DR+ VDG A
Sbjct: 1   MEFKSLTPYGEAIRMASGLRINVRESYVSVAESVGRYCSRDVVSPVDFPEADRSAVDGIA 60

Query: 61  VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120
           +R ED+  AS +NPI+L +VGE+  G+ P   + +GE   + TG+ +P+ A+AV+  ED 
Sbjct: 61  LRYEDSLSASRSNPIQLSLVGEVRIGDSPAFRINRGECAIVYTGSPIPEGANAVLMKEDA 120

Query: 121 ERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRK 180
                 + +Y+       + + G D+ +G  ++++G R+           G+++V V   
Sbjct: 121 SIGKSMVSVYRQMKKFQNISRAGEDLKRGDTIIKRGSRIMPWHLPAFIESGIDKVPVM-D 179

Query: 181 PKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELI 240
            ++ I+STG EIV        G + + +   L   ++ +G +  F G   DD   ++ +I
Sbjct: 180 AEIGIVSTGTEIV-------RGLVKNSSAPMLEAMISRMGLKSAFYGNVEDDESRIRSVI 232

Query: 241 EEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGL 300
            EG++ +DI++++GG+    +DL   +I   G++  HG+ ++PG+ T +G ++GKPVF +
Sbjct: 233 -EGMK-SDIIIVTGGSGPSSQDLVHDIIASNGQLIFHGVRMKPGRTTGLGMMDGKPVFMI 290

Query: 301 PGYPTSCLTNFTLLVVPLLLRALGREGKVRKV-KARLKHKIFSVKGRRQFLPVKL---EG 356
            G P + L  F  ++ P +    G +   R+  +  L   IF+ +  R F+ V++   +G
Sbjct: 291 SGLPVAALIAFENIIDPAIRSWFGMKSLERRTRRGYLTRSIFNNENMRMFVRVRMFEEDG 350

Query: 357 GVAVPILK--GSGAVTSFIDADGFIEIPETVESVDEGEEVEV 396
              V  ++  GSG + S I ADG++ I E  E   EG EV+V
Sbjct: 351 KTMVEPMRTTGSGVINSVISADGYLVIEENSEGYPEGAEVDV 392


>sp|Q39054|CNX1_ARATH MOLYBDOPTERIN BIOSYNTHESIS CNX1 PROTEIN (MOLYBDENUM COFACTOR
           BIOSYNTHESIS ENZYME CNX1) >gi|1263314|gb|AAA97413.1|
           (L47323) molybdenum cofactor biosynthesis enzyme
           [Arabidopsis thaliana] >gi|4469123|emb|CAB38312.1|
           (AJ236870) molybdenum cofactor biosynthesis enzyme
           [Arabidopsis thaliana]
           Length = 670
           
 Score =  202 bits (509), Expect = 5e-51
 Identities = 144/425 (33%), Positives = 213/425 (49%), Gaps = 38/425 (8%)

Query: 5   KVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAE 64
           +++P E AL IV   +  L    V L EALG+++AEDI +P  +PP+  +  DGYAV A 
Sbjct: 15  EMIPTEEALRIVFGVSKRLPPVIVSLYEALGKVLAEDIRAPDPLPPYPASVKDGYAVVAS 74

Query: 65  DTFMASEANPIKLKVVGEIHAGEEPK-LELKKGETVYISTGAMLPKNADAVIQFEDVERV 123
           D        P +  V+ E  AG +   + +  G   Y++TG  +P  ADAV+Q ED + +
Sbjct: 75  D-------GPGEYPVITESRAGNDGLGVTVTPGTVAYVTTGGPIPVGADAVVQVEDTKVI 127

Query: 124 GD------EIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRV 177
           GD       + I      G  + + G DI K   ++  GER+G  +  LL+  GV  V+V
Sbjct: 128 GDVSTEAKRVKILIQTKKGTDIRRVGCDIEKDATVLTTGERIGASEIGLLATAGVTMVKV 187

Query: 178 FRKPKVAIISTGNEIVLP-GSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESL 236
           +  P VAI+STG+E+V P    L  GQI D N   L  AV +   + + LGI RDDR+ L
Sbjct: 188 YPMPIVAILSTGDELVEPTAGTLGRGQIRDSNRAMLVAAVMQQQCKVVDLGIVRDDRKEL 247

Query: 237 KELIEEGVRV-ADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGK 295
           +++++E V    DI++ SGG S G RD    ++EE G+V    + ++PGKP    EI  K
Sbjct: 248 EKVLDEAVSSGVDIILTSGGVSMGDRDFVKPLLEEKGKVYFSKVLMKPGKPLTFAEIRAK 307

Query: 296 P----------VFGLPGYPTSCLTNFTLLVVPLLLRALG-REGKVRKVKARLKHKIFSVK 344
           P           FGLPG P SCL  F + VVP + +  G       +V+ RL+  I S  
Sbjct: 308 PTESMLGKTVLAFGLPGNPVSCLVCFNIFVVPTIRQLAGWTSPHPLRVRLRLQEPIKSDP 367

Query: 345 GRRQF----LPVKLEGGVAVP--ILKGSG-----AVTSFIDADGFIEIPETVESVDEGEE 393
            R +F    +  K   G   P  + + +G      + S   A+  +E+P T   +  G  
Sbjct: 368 IRPEFHRAIIKWKDNDGSGTPGFVAESTGHQMSSRLLSMRSANALLELPATGNVLSAGSS 427

Query: 394 VEVTL 398
           V   +
Sbjct: 428 VSAII 432


>sp|P45210|MOEA_HAEIN MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|1075033|pir||B64124
           molybdopterin biosynthesis protein moeA - Haemophilus
           influenzae (strain Rd KW20) >gi|1574287|gb|AAC23098.1|
           (U32823) molybdopterin biosynthesis protein (moeA)
           [Haemophilus influenzae Rd]
           Length = 404
           
 Score =  200 bits (504), Expect = 2e-50
 Identities = 130/395 (32%), Positives = 204/395 (50%), Gaps = 14/395 (3%)

Query: 14  EIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEAN 73
           +++     P  TE + L EA  RI AEDI SPI++P FD + +DGYAVR  D   +    
Sbjct: 10  KMLEQLPFPTQTEYLNLQEAANRICAEDIISPINVPSFDNSAMDGYAVRLSDLQQS---- 65

Query: 74  PIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPA 133
            + L V G+  AG   + E      V I TGAM+P+  DAVI  E V    D  I +   
Sbjct: 66  -LTLSVAGKSFAGNPFQEEWPSKSAVRIMTGAMIPEGTDAVIMQEQVTLNEDGTITFSEL 124

Query: 134 -YPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEI 192
             P   + + G D+ KG +++ +G +L      LL+++G+  V+ +R+ KV ++STG+E+
Sbjct: 125 PKPNQNIRRIGEDVKKGDVVLEQGAQLTPVSLPLLASLGIAEVKCYRQLKVGVLSTGDEL 184

Query: 193 VLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVI 252
           V  G  L+ GQIYD N   +   + +L  E I LG+  D+    ++        AD+V+ 
Sbjct: 185 VEVGKPLQSGQIYDTNRFTVKLLLEKLHCEVIDLGLLPDNEAEFEKAFIAAQSQADLVIT 244

Query: 253 SGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFT 312
           SGG S G  D T +V+E++G+V    IAI+PGKP   G++      GLPG P S L  F 
Sbjct: 245 SGGVSVGEADFTKAVLEKVGQVNFWKIAIKPGKPFAFGKLENAWFCGLPGNPVSALVTFY 304

Query: 313 LLVVPLLLRALGREGKVRK------VKARLKHKIFSVKGRRQFLPVKLEGGVAVPIL--K 364
            LV PL+ +  G++   +           LK  +  +  +R F  +  +G + V  +  +
Sbjct: 305 QLVQPLIAKLQGQKQWKKPPHFSAIATMNLKKAVGRLDFQRGFYYINEQGQIEVQSVGFQ 364

Query: 365 GSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLF 399
           GS   ++F+ ++ FI + +   +V  GE V +  F
Sbjct: 365 GSHLFSAFVKSNCFIVLEQERGNVSAGETVTIEPF 399


>pir||C83266 molybdenum cofactor biosynthesis protein A2 PA3028 [imported] -
           Pseudomonas aeruginosa (strain PAO1)
           >gi|9949132|gb|AAG06416.1|AE004728_2 (AE004728)
           molybdenum cofactor biosynthesis protein A2 [Pseudomonas
           aeruginosa]
           Length = 405
           
 Score =  200 bits (504), Expect = 2e-50
 Identities = 142/391 (36%), Positives = 213/391 (54%), Gaps = 17/391 (4%)

Query: 9   LERALEIVNSFTLPLGT-EEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTF 67
           LER LE+      P+ T E+V L +A GR++A D+ + +D+PP+  + +DGYA+R  D  
Sbjct: 17  LERLLELAAQ--TPIDTCEQVPLEQAGGRVLAVDLLAGLDLPPWPNSAMDGYALRLADW- 73

Query: 68  MASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEI 127
                N   L V  +I AG+ PK  L+ G    I TGA LP+ AD V   E+ E + D  
Sbjct: 74  -----NGEPLPVSQKIFAGQAPK-PLQAGTCARIFTGAPLPEGADLVEMQENAEALDDGR 127

Query: 128 IIY-KPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAII 186
           + + +P   G  V  +G +I +G L++  G RL   +  L +++G   + V RKP+VA++
Sbjct: 128 VRFTQPLRVGQHVRPRGQEIRQGDLVLPAGTRLRSIELGLAASLGYAALEVRRKPRVALL 187

Query: 187 STGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRV 246
           STG+E+V  G  L+ GQIY+ N   L D +  LG + +  GI  DD    +E +  G+  
Sbjct: 188 STGDELVEAGQPLQAGQIYNSNRPLLKDWLQRLGCDVLDAGILPDDLARTRERLA-GLAG 246

Query: 247 ADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTS 306
            D+++ +GG S G  D     + E GE+ +  +AI+PGKP  +G+  G PV GLPG P S
Sbjct: 247 VDLILSTGGVSVGEADFLGMALREAGELTLWKLAIKPGKPLTVGQFQGIPVIGLPGNPAS 306

Query: 307 CLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKG--RRQFLPVKLEGGVAVPI-L 363
            L  F LL  P LLR LG   +V  ++  +       K   RR++L  +LE G AV    
Sbjct: 307 TLVTFALLARPYLLRRLG-VAQVAPLRVEVPAGFAWTKAGQRREYLRGRLEQGRAVLYPN 365

Query: 364 KGSGAVTSFIDADGFIEIPETVESVDEGEEV 394
           + SG + S   A+G +E+ E   ++ EGE V
Sbjct: 366 QSSGVLRSASWAEGLVEVREG-RTLVEGEGV 395


>pir||E82439 molybdopterin biosynthesis MoeA protein VCA0617 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9658029|gb|AAF96518.1| (AE004391) molybdopterin
           biosynthesis MoeA protein [Vibrio cholerae]
           Length = 435
           
 Score =  198 bits (499), Expect = 8e-50
 Identities = 139/404 (34%), Positives = 202/404 (49%), Gaps = 16/404 (3%)

Query: 6   VVPLERALEIVNSFTLPLGTE-EVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAE 64
           ++P+E AL+ + S   P+ T   + L EALG ++AE I SPI +PPFD + +DGYAVR  
Sbjct: 33  LMPIEDALKKMLSRIQPVQTTLRLPLPEALGYVLAEAILSPIHVPPFDNSAMDGYAVRR- 91

Query: 65  DTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVG 124
               A  A    L V G+  AG+    +      V I TGA +P   DAVI  E    + 
Sbjct: 92  ----AELAQQKPLPVAGKSFAGQPFTADWPPMTCVRIMTGAQIPAGCDAVIMQEQAT-IT 146

Query: 125 DEIIIYKPAYPGLG--VMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPK 182
           +E +++      L   +   G DI +  +++ +G RL  +   +++ +G+  V V+RKPK
Sbjct: 147 EEGVVFCQHEVKLNDNIRPTGDDIRQNDVVLERGARLTARDIPMIATLGISHVTVYRKPK 206

Query: 183 VAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEE 242
           VA  STG+E+   G  L+ GQIYD N   +   +   G E I LGI  D   +LK   E+
Sbjct: 207 VAFFSTGDELKPLGEPLQAGQIYDSNRYGIKPLIENFGCEAIDLGIVPDCPATLKATFEQ 266

Query: 243 GVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPG 302
              +AD+VV SGG S G  D T  ++EELGE+    +AI+PGKP   G +      GLPG
Sbjct: 267 AQSLADVVVTSGGVSVGEADYTKDILEELGEIGFWKLAIKPGKPFAFGALQDAWFCGLPG 326

Query: 303 YPTSCLTNFTLLVVPLLLRALGREG--KVRKVKARLKHKIFSVKGRRQFLP--VKLEGGV 358
            P S +    +LV P+L +  G         + A  +       GR  F     ++E G 
Sbjct: 327 NPVSAVLTMYVLVQPMLAKLAGHSAWQAPESIPAITRSPFKKAPGRTDFQRGIYRIENGQ 386

Query: 359 AVPILKG---SGAVTSFIDADGFIEIPETVESVDEGEEVEVTLF 399
            V    G   SGA  S   A+ F+ +      V+ GE V++ LF
Sbjct: 387 FVVESTGNQSSGAFRSMSLANCFVVLERERGRVEVGETVQIQLF 430


>dbj|BAA92623.1| (AB037806) KIAA1385 protein [Homo sapiens]
           Length = 768
           
 Score =  198 bits (497), Expect = 1e-49
 Identities = 136/425 (32%), Positives = 214/425 (50%), Gaps = 41/425 (9%)

Query: 1   MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60
           M+   +  +++A   V   T  LGTE +   + +GR++A+D+Y+  ++PPF  +  DGYA
Sbjct: 350 MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYA 409

Query: 61  VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120
           VRA D        P    ++GE  AGE+P   +  G+ + ++TGA +P  ADAV+Q ED 
Sbjct: 410 VRAAD-------GPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDT 462

Query: 121 ERVGD--------EIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGV 172
           E + +        E+ I   A PG  +   G DI +G  ++ KG  +G  +  LL+ VGV
Sbjct: 463 ELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGV 522

Query: 173 ERVRVFRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDD 232
             V V + P VA++STGNE++ P  +L PG+I D N   L   + E G   I LGI  D+
Sbjct: 523 TEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDN 582

Query: 233 RESLKELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVH--GIAIQPGKPTIIG 290
            + L   + EG+  AD+++ SGG S G +D    V++     ++H   + ++PG PT   
Sbjct: 583 PDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFA 642

Query: 291 --EING--KPVFGLPGYPTSCLTNFTLLVVPLLLRALG-REGKVRKVKARLK-------- 337
             +I+G  K +F LPG P S +    L VVP L +  G  + +   +KARL         
Sbjct: 643 TLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPR 702

Query: 338 ---HKIFSVKGRRQFLPVKLEGGVAVPILKGSGAVTSFIDADGFIEIPETVE---SVDEG 391
              H+       ++ LP     G  +     S  + S   A+G + +P   E    + +G
Sbjct: 703 PEYHRCILTWHHQEPLPWAQSTGNQM-----SSRLMSMRSANGLLMLPPKTEQYVELHKG 757

Query: 392 EEVEV 396
           E V+V
Sbjct: 758 EVVDV 762


>gb|AAF81785.1|AF272663_1 (AF272663) gephyrin [Homo sapiens]
           Length = 736
           
 Score =  198 bits (497), Expect = 1e-49
 Identities = 136/425 (32%), Positives = 214/425 (50%), Gaps = 41/425 (9%)

Query: 1   MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60
           M+   +  +++A   V   T  LGTE +   + +GR++A+D+Y+  ++PPF  +  DGYA
Sbjct: 318 MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYA 377

Query: 61  VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120
           VRA D        P    ++GE  AGE+P   +  G+ + ++TGA +P  ADAV+Q ED 
Sbjct: 378 VRAAD-------GPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDT 430

Query: 121 ERVGD--------EIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGV 172
           E + +        E+ I   A PG  +   G DI +G  ++ KG  +G  +  LL+ VGV
Sbjct: 431 ELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGV 490

Query: 173 ERVRVFRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDD 232
             V V + P VA++STGNE++ P  +L PG+I D N   L   + E G   I LGI  D+
Sbjct: 491 TEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDN 550

Query: 233 RESLKELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVH--GIAIQPGKPTIIG 290
            + L   + EG+  AD+++ SGG S G +D    V++     ++H   + ++PG PT   
Sbjct: 551 PDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFA 610

Query: 291 --EING--KPVFGLPGYPTSCLTNFTLLVVPLLLRALG-REGKVRKVKARLK-------- 337
             +I+G  K +F LPG P S +    L VVP L +  G  + +   +KARL         
Sbjct: 611 TLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPR 670

Query: 338 ---HKIFSVKGRRQFLPVKLEGGVAVPILKGSGAVTSFIDADGFIEIPETVE---SVDEG 391
              H+       ++ LP     G  +     S  + S   A+G + +P   E    + +G
Sbjct: 671 PEYHRCILTWHHQEPLPWAQSTGNQM-----SSRLMSMRSANGLLMLPPKTEQYVELHKG 725

Query: 392 EEVEV 396
           E V+V
Sbjct: 726 EVVDV 730


>gi|10880983 gephyrin; gephryin [Homo sapiens] >gi|10636475|emb|CAC10537.1|
           (AJ272343) gephyrin [Homo sapiens]
           Length = 769
           
 Score =  198 bits (497), Expect = 1e-49
 Identities = 136/425 (32%), Positives = 214/425 (50%), Gaps = 41/425 (9%)

Query: 1   MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60
           M+   +  +++A   V   T  LGTE +   + +GR++A+D+Y+  ++PPF  +  DGYA
Sbjct: 351 MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYA 410

Query: 61  VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120
           VRA D        P    ++GE  AGE+P   +  G+ + ++TGA +P  ADAV+Q ED 
Sbjct: 411 VRAAD-------GPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDT 463

Query: 121 ERVGD--------EIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGV 172
           E + +        E+ I   A PG  +   G DI +G  ++ KG  +G  +  LL+ VGV
Sbjct: 464 ELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGV 523

Query: 173 ERVRVFRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDD 232
             V V + P VA++STGNE++ P  +L PG+I D N   L   + E G   I LGI  D+
Sbjct: 524 TEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDN 583

Query: 233 RESLKELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVH--GIAIQPGKPTIIG 290
            + L   + EG+  AD+++ SGG S G +D    V++     ++H   + ++PG PT   
Sbjct: 584 PDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFA 643

Query: 291 --EING--KPVFGLPGYPTSCLTNFTLLVVPLLLRALG-REGKVRKVKARLK-------- 337
             +I+G  K +F LPG P S +    L VVP L +  G  + +   +KARL         
Sbjct: 644 TLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPR 703

Query: 338 ---HKIFSVKGRRQFLPVKLEGGVAVPILKGSGAVTSFIDADGFIEIPETVE---SVDEG 391
              H+       ++ LP     G  +     S  + S   A+G + +P   E    + +G
Sbjct: 704 PEYHRCILTWHHQEPLPWAQSTGNQM-----SSRLMSMRSANGLLMLPPKTEQYVELHKG 758

Query: 392 EEVEV 396
           E V+V
Sbjct: 759 EVVDV 763


>sp|Q03555|GEPH_RAT GEPHYRIN (PUTATIVE GLYCINE RECEPTOR-TUBULIN LINKER PROTEIN)
           >gi|111656|pir||JH0681 gephyrin - rat
           >gi|56312|emb|CAA47009.1| (X66366) Gephyrin [Rattus
           norvegicus]
           Length = 736
           
 Score =  198 bits (497), Expect = 1e-49
 Identities = 136/425 (32%), Positives = 214/425 (50%), Gaps = 41/425 (9%)

Query: 1   MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60
           M+   +  +++A   V   T  LGTE +   + +GR++A+D+Y+  ++PPF  +  DGYA
Sbjct: 318 MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYA 377

Query: 61  VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120
           VRA D        P    ++GE  AGE+P   +  G+ + ++TGA +P  ADAV+Q ED 
Sbjct: 378 VRAAD-------GPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDT 430

Query: 121 ERVGD--------EIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGV 172
           E + +        E+ I   A PG  +   G DI +G  ++ KG  +G  +  LL+ VGV
Sbjct: 431 ELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGV 490

Query: 173 ERVRVFRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDD 232
             V V + P VA++STGNE++ P  +L PG+I D N   L   + E G   I LGI  D+
Sbjct: 491 TEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDN 550

Query: 233 RESLKELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVH--GIAIQPGKPTIIG 290
            + L   + EG+  AD+++ SGG S G +D    V++     ++H   + ++PG PT   
Sbjct: 551 PDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFA 610

Query: 291 --EING--KPVFGLPGYPTSCLTNFTLLVVPLLLRALG-REGKVRKVKARLK-------- 337
             +I+G  K +F LPG P S +    L VVP L +  G  + +   +KARL         
Sbjct: 611 TLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPR 670

Query: 338 ---HKIFSVKGRRQFLPVKLEGGVAVPILKGSGAVTSFIDADGFIEIPETVE---SVDEG 391
              H+       ++ LP     G  +     S  + S   A+G + +P   E    + +G
Sbjct: 671 PEYHRCILTWHHQEPLPWAQSTGNQM-----SSRLMSMRSANGLLMLPPKTEQYVELHKG 725

Query: 392 EEVEV 396
           E V+V
Sbjct: 726 EVVDV 730


>gi|11435181 gephyrin [Homo sapiens]
           Length = 419
           
 Score =  198 bits (497), Expect = 1e-49
 Identities = 136/425 (32%), Positives = 214/425 (50%), Gaps = 41/425 (9%)

Query: 1   MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60
           M+   +  +++A   V   T  LGTE +   + +GR++A+D+Y+  ++PPF  +  DGYA
Sbjct: 1   MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYA 60

Query: 61  VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120
           VRA D        P    ++GE  AGE+P   +  G+ + ++TGA +P  ADAV+Q ED 
Sbjct: 61  VRAAD-------GPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDT 113

Query: 121 ERVGD--------EIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGV 172
           E + +        E+ I   A PG  +   G DI +G  ++ KG  +G  +  LL+ VGV
Sbjct: 114 ELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGV 173

Query: 173 ERVRVFRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDD 232
             V V + P VA++STGNE++ P  +L PG+I D N   L   + E G   I LGI  D+
Sbjct: 174 TEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDN 233

Query: 233 RESLKELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVH--GIAIQPGKPTIIG 290
            + L   + EG+  AD+++ SGG S G +D    V++     ++H   + ++PG PT   
Sbjct: 234 PDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFA 293

Query: 291 --EING--KPVFGLPGYPTSCLTNFTLLVVPLLLRALG-REGKVRKVKARLK-------- 337
             +I+G  K +F LPG P S +    L VVP L +  G  + +   +KARL         
Sbjct: 294 TLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPR 353

Query: 338 ---HKIFSVKGRRQFLPVKLEGGVAVPILKGSGAVTSFIDADGFIEIPETVE---SVDEG 391
              H+       ++ LP     G  +     S  + S   A+G + +P   E    + +G
Sbjct: 354 PEYHRCILTWHHQEPLPWAQSTGNQM-----SSRLMSMRSANGLLMLPPKTEQYVELHKG 408

Query: 392 EEVEV 396
           E V+V
Sbjct: 409 EVVDV 413


>pir||G70829 probable molybdenum cofactor biosynthesis protein - Mycobacterium
           tuberculosis (strain H37RV) >gi|2909513|emb|CAA17395.1|
           (AL021932) moaA3 [Mycobacterium tuberculosis]
           Length = 405
           
 Score =  196 bits (493), Expect = 4e-49
 Identities = 123/379 (32%), Positives = 197/379 (51%), Gaps = 10/379 (2%)

Query: 28  VKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIHAGE 87
           V L++A G ++  D+ +P+ +P FD + +DGYAVRAEDT  A+  NP+ L V  +I AG 
Sbjct: 23  VPLTQAQGLVLGGDVVAPLSLPVFDNSAMDGYAVRAEDTSGATPQNPVMLPVAEDIPAGR 82

Query: 88  EPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAYPGLGVMKKGVDIS 147
              L L+      I TGA +P  A A++  E  +   D + I + A PG  + + G D++
Sbjct: 83  ADMLTLQPVTAHRIMTGAPVPTGATAIVPVEATDGGVDSVAIRQQATPGKHIRRSGEDVA 142

Query: 148 KGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELKPGQIYDI 207
            G  ++  G+ +      L +A+G+  + V  + +V +ISTG+E+  PG+ L+PGQIY+ 
Sbjct: 143 AGTTVLHNGQIVTPAVLGLAAALGLAELPVLPRQRVLVISTGSELASPGTPLQPGQIYES 202

Query: 208 NGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISGGASGG----MRDL 263
           N   L+ AV + G   +    A DD      +++     AD+++ SGG S G    ++D 
Sbjct: 203 NSIMLAAAVRDAGAAVVATATAGDDVAQFGAILDRYAVDADLIITSGGVSAGAYEVVKDA 262

Query: 264 TASVIEELGE--VKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFTLLVVPLLLR 321
             S     G+  V+   +A+QPG P  +G + G P+  LPG P S L +F + + P L  
Sbjct: 263 FGSADYRGGDHGVEFVKVAMQPGMPQGVGRVAGTPIVTLPGNPVSALVSFEVFIRPPLRM 322

Query: 322 ALGREGKVRKVK-ARLKHKIFSVKGRRQFLPVKLEGGVAVPILKGSGA---VTSFIDADG 377
           A+G     R  + A L   + S +G+RQF    L+      I  G  A   +     A+G
Sbjct: 323 AMGLPDPYRPHRSAVLTASLTSPRGKRQFRRAILDHQAGTVISYGPPASHHLRWLASANG 382

Query: 378 FIEIPETVESVDEGEEVEV 396
            ++IPE V  V  G +++V
Sbjct: 383 LLDIPEDVVEVAAGTQLQV 401


>emb|CAA67416.1| (X98917) orf5 [Methanopyrus kandleri]
           Length = 408
           
 Score =  195 bits (491), Expect = 7e-49
 Identities = 132/381 (34%), Positives = 202/381 (52%), Gaps = 18/381 (4%)

Query: 10  ERALEIVNSFTLPLGTEEVKLSEAL-GRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFM 68
           E  +  +  F  P   E V++   L GR++AED+ +    PPF R+ +DGYAVR+ED   
Sbjct: 19  EEFIRFLRRFLSPPEPETVEVGPELSGRVLAEDVRAERPSPPFTRSAMDGYAVRSED--- 75

Query: 69  ASEANP-IKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEI 127
              A P  +LKVVGE   GE   +++  GE VY+ TGA +P+ ADAVI  E VER GDEI
Sbjct: 76  ---AEPGARLKVVGESRIGEGTDVKVGPGEAVYVDTGAPVPEGADAVIPVEFVERDGDEI 132

Query: 128 IIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIIS 187
           I+ +   PG  +   G  + +G +L R G  +      ++   GVE V V R  +V+I+ 
Sbjct: 133 IVEEGVDPGDNLDPAGCYVEEGEVLYRSGHLVEPVDVGVMLEHGVEEVDVHRPLRVSIVV 192

Query: 188 TGNEIVLPGSELK-PGQIYDINGRALSDAVNELG-GEGIFLGIARDDRESLKELIEEGVR 245
           TGNE+V   SEL+   Q+ D  G  L+  +  +G  E +   + +DD   ++E +E+   
Sbjct: 193 TGNELVHRPSELESETQVVDCIGPVLTAELENMGCVEVVGTSLVKDDPGEIRETVEDYAD 252

Query: 246 VADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPT 305
            +D+V+I+GG+S G RD    ++++  +  +HGI  +PG+P  I    G   F LPG+PT
Sbjct: 253 RSDVVLITGGSSVGERDHVKDILDDTFDAFIHGIRARPGRPFGIAAREGTVAFTLPGWPT 312

Query: 306 SCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQ---FLPVKLEGGVAVPI 362
           SC + F + VVP LL   G +  V       + +   +K +R+      V+L    A  +
Sbjct: 313 SCYSTFRVWVVPSLLVLAGADPLV----VGFETEATGIKSKREVGVIARVRLTSDGAEGL 368

Query: 363 LKG-SGAVTSFIDADGFIEIP 382
            +  S     F + DGF  +P
Sbjct: 369 SRDRSSHFALFRETDGFALVP 389


>pir||E69659 molybdopterin biosynthesis protein moeA - Bacillus subtilis
           >gi|2633799|emb|CAB13301.1| (Z99111) molybdopterin
           biosynthesis protein [Bacillus subtilis]
           >gi|3282112|gb|AAC24902.1| (AF012285) molybdopterin
           biosynthesis protein MoeA [Bacillus subtilis]
           Length = 430
           
 Score =  192 bits (484), Expect = 4e-48
 Identities = 135/416 (32%), Positives = 205/416 (48%), Gaps = 37/416 (8%)

Query: 7   VPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDT 66
           +P++ A+  V  F     TE V L ++L R +AEDI +   +P FDR+  DG+AVRA DT
Sbjct: 8   IPVDEAVRRVCHFQKQGETEWVALEDSLHRFLAEDITADHHVPAFDRSPYDGFAVRACDT 67

Query: 67  FMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFE---DVERV 123
             AS  NP++ +V+  I AG   + EL   + V I TGA +P+ ADAV+  E     E  
Sbjct: 68  AEASRENPVRFEVIDHIGAGAVSEKELGPFQAVRIMTGAQIPEGADAVVMIELTQAFEEN 127

Query: 124 GDEIIIYKPAY-PGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPK 182
           G   +  K  +  G  + K G D  KG +L+ KG R+    TALL+  G   V V RKP 
Sbjct: 128 GKSFMSLKRRFQTGDNISKTGEDAQKGSVLLTKGTRVTPGVTALLATFGYASVPVVRKPV 187

Query: 183 VAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEE 242
           V II+TG E++     L+PG+I + N   +     E G   ++LG   D+ +     ++E
Sbjct: 188 VGIIATGTELLNVSDPLEPGKIRNSNASMVYAQAIEAGATPLYLGKISDELDKSFAAVKE 247

Query: 243 GVRVADIVVISGGASGGMRDLTASVIEELG-EVKVHGIAIQPGKPTIIGEINGKPVFGLP 301
            ++  D ++ +GG S G  D   ++ E+LG +V  + +A++PG  T +   N   +FGL 
Sbjct: 248 AMKKVDFLITTGGVSVGDFDFLPAIYEKLGADVLFNKVAMRPGSVTTVAHANDMLLFGLS 307

Query: 302 GYPTSCLTNFTLLVVPLLLRALGREGK-------------------VRKVKARLKHKIFS 342
           G P++C   F L V P++   L  E                      R V+A + H+   
Sbjct: 308 GNPSACYVGFELFVKPIIQTWLLNETPHSICAEAVLTKDFPKPNPFTRFVRALVHHQ--- 364

Query: 343 VKGRRQFLPVKLEGGVAVPILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTL 398
            +G+    PV L+          S +VTS  DA+ FI +P      + G  V+V L
Sbjct: 365 -EGKLLATPVGLD---------KSSSVTSLADANAFIILPGGTRGYESGRTVQVLL 410


>gb|AAC83139.1| (AF109295) MoeA [Staphylococcus carnosus]
           Length = 419
           
 Score =  191 bits (481), Expect = 1e-47
 Identities = 125/401 (31%), Positives = 204/401 (50%), Gaps = 7/401 (1%)

Query: 7   VPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDT 66
           +P+  A++ V    +    + V L+++LG ++AEDI +  +IP F+++  DG+A+R+EDT
Sbjct: 9   IPVREAIKRVVEQDIETEVQNVPLNKSLGYVLAEDIVATYEIPRFNKSPYDGFALRSEDT 68

Query: 67  FMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDE 126
             AS  N I+ +V+  I AG      +   + V I TGA +P  ADAV+  E  +     
Sbjct: 69  VGASGDNRIEFEVIDHIGAGSVSDKTVGPNQAVRIMTGAEVPAGADAVVMLEQTKEGDHT 128

Query: 127 IIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAII 186
             I K       V  KG +   G ++++KG+R+     A+L+  G   V V + P  AII
Sbjct: 129 FTIRKTFSHNENVSLKGEETEVGDVVLKKGQRINAGGIAVLATFGYTEVPVRKLPSAAII 188

Query: 187 STGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRV 246
           +TG+E++  G EL+PG+I + NG  +   +N+ G +G    I  DD ES   ++++ +  
Sbjct: 189 ATGSELLDVGDELEPGKIRNSNGPMIEGLLNQFGLDGEVYKIQEDDLESSIAVVKQAMET 248

Query: 247 ADIVVISGGASGGMRDLTASVIEEL-GEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPT 305
            D+V+ +GG S G  D    + + L  EV  + + ++PG  T +   +GK +FGL G P+
Sbjct: 249 HDMVITTGGVSVGDFDYLPEIYKALDAEVLFNKVQMRPGSVTTVAVAHGKYLFGLSGNPS 308

Query: 306 SCLTNFTLLVVPLLLRALGREGKV-RKVKARLKHKIFSVKGRRQFLPVK--LEGGVAVPI 362
           +C T F L V   +L  +G   K  + VKA L           +F+  K  L G  A  +
Sbjct: 309 ACYTGFQLFVKTGVLNMMGANEKFPQVVKATLMEDFKKANPFTRFIRSKATLNGMEATVV 368

Query: 363 LKG---SGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFE 400
             G   SGAV +   ++  + +P        G  V+V L E
Sbjct: 369 PSGFNKSGAVVAIAHSNAMVMLPSGTRGFHAGNTVDVILTE 409


>sp|Q44243|MOEA_ANASP MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|1002858|gb|AAC44505.1|
           (U34309) moeA gene product [Anabaena sp.]
           Length = 436
           
 Score =  190 bits (477), Expect = 3e-47
 Identities = 112/304 (36%), Positives = 164/304 (53%), Gaps = 5/304 (1%)

Query: 25  TEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIH 84
           TE V L  A GRI+A  + S +D P +D + +DGYAVR ED   ++   P+ L+VV EI 
Sbjct: 48  TEIVDLWAANGRILATPVNSTLDFPHWDNSAMDGYAVRYEDVHNSNAEQPVSLEVVAEIP 107

Query: 85  AGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAYPGLGVMKKGV 144
           AG +PK  L+ G+   I TGA++P   D V+  E   +  + + I     PG  V  K  
Sbjct: 108 AGYQPKFTLQPGQAARIFTGAVMPSGGDTVVMQEKTRQENNRVFILTTPKPGEFVRLKAA 167

Query: 145 DISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELKPGQI 204
               G  L+    +L   + A+L+A    +V+V+R+P+VAI STG+E+V     L+PGQI
Sbjct: 168 YYQAGTQLLPANTQLNAAEIAILAASQCPQVKVYRRPRVAIFSTGDELVTLDQPLQPGQI 227

Query: 205 YDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISGGASGGMRDLT 264
            D N  AL+  V + G E I  GI +D+  +L E I + +  ADIV+ SGG S G  D  
Sbjct: 228 VDSNQYALAALVKQNGAEPILFGIVKDNPTALGETISKAIANADIVISSGGVSVGDYDYV 287

Query: 265 ASVIEELG-EVKVHGIAIQPGKPTIIGEINGKPV---FGLPGYPTSCLTNFTLLVVPLLL 320
             ++  LG ++ +  + ++PGKP  +      P     GLPG P + L  F   V P ++
Sbjct: 288 DQILASLGAKIHIRSVEMRPGKPLTVATFPTPPAPIYLGLPGNPAAVLVTFWRFVQP-VI 346

Query: 321 RALG 324
           R LG
Sbjct: 347 RKLG 350


>sp|O05577|MOEA_MYCTU MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|7445251|pir||E70601
           probable MoeAprotein - Mycobacterium tuberculosis
           (strain H37RV) >gi|2052128|emb|CAB08154.1| (Z94752) moeA
           [Mycobacterium tuberculosis]
           Length = 426
           
 Score =  187 bits (471), Expect = 1e-46
 Identities = 128/397 (32%), Positives = 203/397 (50%), Gaps = 28/397 (7%)

Query: 28  VKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIK----------- 76
           V ++EA G + AE++ +   +P FD+A +DGYAVR+ D     +   ++           
Sbjct: 23  VAIAEAQGLMCAEEVVTERPMPGFDQAAIDGYAVRSVDVAGVGDTGGVQVFADHGDLDGR 82

Query: 77  ----LKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKP 132
               L V+G I AG      L+  + V + TGA LP  ADAV+     +     + + + 
Sbjct: 83  DVLTLPVMGTIEAGARTLSRLQPRQAVRVQTGAPLPTLADAVLPLRWTDGGMSRVRVLRG 142

Query: 133 AYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEI 192
           A  G  V + G D+  G + VR G  +G  Q  LL+AVG ERV V  +P++++++ G E+
Sbjct: 143 APSGAYVRRAGDDVQPGDVAVRAGTIIGAAQVGLLAAVGRERVLVHPRPRLSVMAVGGEL 202

Query: 193 VLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVI 252
           V        GQ+YD+N  AL+ A  +   E   +GI  +D   L E++E  +  A++VVI
Sbjct: 203 VDISRTPGNGQVYDVNSYALAAAGRDACAEVNRVGIVSNDPTELGEIVEGQLNRAEVVVI 262

Query: 253 SGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEI--NGKPVFGLPGYPTSCLTN 310
           +GG  G   +   SV+ ELGE++V  +A+ PG     G++  +G P F LP  P S L  
Sbjct: 263 AGGVGGAAAEAVRSVLSELGEMEVVRVAMHPGSVQGFGQLGRDGVPTFLLPANPVSALVV 322

Query: 311 FTLLVVPLLLRALGREGKVRK-VKARLKHKIFSVKGRRQFLPVKL-----EGGVAVPILK 364
           F ++V PL+  +LG+   +R+ V AR    I SV GR+ +L  +L      G   V  L 
Sbjct: 323 FEVMVRPLIRLSLGKRHPMRRIVSARTLSPITSVAGRKGYLRGQLMRDQDSGEYLVQALG 382

Query: 365 GSGAVTSFI-----DADGFIEIPETVESVDEGEEVEV 396
           G+   +S +     +A+  + +P   E +  GE V+V
Sbjct: 383 GAPGASSHLLATLAEANCLVVVPTGAEQIRTGEIVDV 419


>pir||T45454 probable molybdenum cofactor biosynthesis protein [imported] -
           Mycobacterium leprae >gi|4455711|emb|CAB36697.1|
           (AL035500) putative molybdenum cofactor biosynthesis
           protein [Mycobacterium leprae]
           Length = 424
           
 Score =  187 bits (470), Expect = 2e-46
 Identities = 129/395 (32%), Positives = 204/395 (50%), Gaps = 26/395 (6%)

Query: 28  VKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANP------------- 74
           V ++EA G + AE++ +   +P FD+A +DGYAVR+ D     E++              
Sbjct: 23  VAIAEAQGLMCAEEVMTERPLPGFDQAAIDGYAVRSVDVSGIGESDGGESGSSDEDGRYV 82

Query: 75  IKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAY 134
           + L V+G I AG      L   + V + TGA LP  ADAV+     +     + I + A 
Sbjct: 83  LTLPVMGTIEAGARTPSRLLPHQAVRVQTGAPLPVLADAVLPVRWTDGGMSRVRILRGAP 142

Query: 135 PGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVL 194
            G  V + G D+  G + VR G  +G  Q  LL+AVG ERV V  +P+++I++ G E+V 
Sbjct: 143 SGAYVRRVGDDVQPGDVAVRAGTIIGAAQVGLLAAVGRERVLVHPRPRLSIMAVGGELVD 202

Query: 195 PGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISG 254
                  GQ+YD+N  AL+ A  + G E   +GI  ++ +   E++E  +  A++VVI+G
Sbjct: 203 ISRTPGNGQVYDVNSYALTAAGRDAGAEVNRIGIVSNNLKEFGEVVEGQISRAEVVVIAG 262

Query: 255 GASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEI--NGKPVFGLPGYPTSCLTNFT 312
           G  G   +   +V+ E+GE++V  +A+ PG     G++   G P F LP  P S L  F 
Sbjct: 263 GVGGAAAEAVRAVLSEIGEMEVVRVAMHPGSVQGFGQLGREGVPTFLLPANPVSALVVFE 322

Query: 313 LLVVPLLLRALGREGKVRK-VKARLKHKIFSVKGRRQFLPVKL-----EGGVAVPILKGS 366
           ++V PL+  +LG+   +R+ V+AR    I SV GR+ +L  +L      G   V  L G+
Sbjct: 323 VMVRPLIRLSLGKRQPMRRIVQARTLSPITSVAGRKGYLRGQLMRDQDTGEYLVQALGGA 382

Query: 367 GAVTSFI-----DADGFIEIPETVESVDEGEEVEV 396
              +S +     +A+  + IP   E +  GE V+V
Sbjct: 383 LGASSHLLATLAEANCLVVIPSGAEQIRTGEVVDV 417


>sp|Q56066|MOEA_SALTY MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|1256834|gb|AAA96529.1|
           (U53178) moeA gene product [Salmonella typhimurium]
           Length = 412
           
 Score =  185 bits (466), Expect = 6e-46
 Identities = 139/400 (34%), Positives = 201/400 (49%), Gaps = 17/400 (4%)

Query: 6   VVPLERALEIVNSFTLPL-GTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAE 64
           ++PLE AL  + S   PL   E + L    GRI+A DI SP+D+P FD + +DGYAVR  
Sbjct: 9   LMPLETALTQMLSRITPLTAVETLPLVNCFGRILATDIVSPLDVPGFDNSAMDGYAVRVA 68

Query: 65  DTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVG 124
           D    S   P  L V G+  AG+  + E   G  + I TGA +P   +AV+  E  E+  
Sbjct: 69  DL---SADKP--LPVAGKAFAGQPYQGEWPAGTCIRIMTGAPVPAGCEAVVMQEQTEQTD 123

Query: 125 DEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVA 184
           D          G  + ++G DI +  ++   G RL   +  +L+++G+   +V RK +VA
Sbjct: 124 DGERFTADVRCGQNIRRRGEDIRQDAVVFPAGTRLTTAELPVLASLGIADAQVVRKVRVA 183

Query: 185 IISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGG-EGIFLGIARDDRESLKELIEEG 243
           + STG+E+ LPG  L+  QIYD N   +   + +LG  E I LGI  DD   L+  I+  
Sbjct: 184 LFSTGDELQLPGQPLEADQIYDTNRLTIHLMLQQLGWREVINLGIIPDDPGKLRGFIDAD 243

Query: 244 VRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGY 303
            + AD VVIS   S G  D T +++EELGE+    +AI+PGKP   G+++     GLPG 
Sbjct: 244 SQ-AD-VVISSRVSEGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSWFCGLPGN 301

Query: 304 PTSCLTNFTLLVVPLLLRALGREGKV--RKVKARLKHKIFSVKGRRQF----LPVKLEGG 357
           P S    F  LV PLL +  G        + + R   ++    GR  F    L     G 
Sbjct: 302 PVSAALTFYQLVQPLLAKLGGNTASAVPPRQRVRTASRLKKTPGRLDFQRGILQRSANGE 361

Query: 358 VAVPIL--KGSGAVTSFIDADGFIEIPETVESVDEGEEVE 395
           + V     +GS   +SF   + FI +     +V+ GE VE
Sbjct: 362 LEVTTTGHQGSHIFSSFSLGNCFIVLERERGNVEPGEWVE 401


>gb|AAD49748.1|AF174130_1 (AF174130) gephyrin [Gallus gallus]
           Length = 736
           
 Score =  183 bits (459), Expect = 4e-45
 Identities = 117/351 (33%), Positives = 184/351 (52%), Gaps = 22/351 (6%)

Query: 1   MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60
           M+   +  +++A   V   T  LGTE +   + +GR++A+D+Y+  ++PPF  +  DGYA
Sbjct: 318 MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYA 377

Query: 61  VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120
           VRA D        P    ++GE  AGE+P   +  G+ + ++TGA +P  ADAV+Q ED 
Sbjct: 378 VRAAD-------GPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDT 430

Query: 121 ERVGD--------EIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGV 172
           E + +        E+ I   A PG  +   G DI +G  ++ KG   G  +  LL+ VGV
Sbjct: 431 ELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHTGPSEVGLLATVGV 490

Query: 173 ERVRVFRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDD 232
             V V + P VA++STGNE++ P  ++ PG+I D N   L   +   G   I LGI  D+
Sbjct: 491 TEVEVNKFPVVAVMSTGNELLNPEDDVLPGKIRDSNRSTLLATIQAHGYPTINLGIVGDN 550

Query: 233 RESLKELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVH--GIAIQPGKPTIIG 290
            + L   + E +  AD+++ SGG S G +     V++     ++H   + ++PG PT   
Sbjct: 551 PDDLLNALNERISRADVIITSGGVSMGGKYYLKQVLDIDLHAQIHFGRVFMKPGLPTTFA 610

Query: 291 --EING--KPVFGLPGYPTSCLTNFTLLVVPLLLRALG-REGKVRKVKARL 336
             +I+G  K +F LPG   S +    L VVP L +  G  + +   +KARL
Sbjct: 611 TLDIDGVRKIIFALPGQSVSAVVTCNLFVVPALRKMQGILDPRPTIIKARL 661


>pir||B75562 molybdopterin biosynthesis MoeA - Deinococcus radiodurans  (strain
           R1) >gi|6457741|gb|AAF09669.1|AE001871_1 (AE001871)
           molybdopterin biosynthesis MoeA [Deinococcus
           radiodurans]
           Length = 401
           
 Score =  181 bits (455), Expect = 1e-44
 Identities = 137/379 (36%), Positives = 194/379 (51%), Gaps = 21/379 (5%)

Query: 30  LSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIHAGEEP 89
           L +ALG  +  D+ + +  P    + +DG A R  DT  AS   P+ L+VVGE  AGE  
Sbjct: 33  LRKALGCTLGADLTALVSHPSATESALDGIACREADTLTASAGAPVALRVVGESRAGEPF 92

Query: 90  KLELKKGETVYISTGAMLPKNADAVIQFED---------VERVGDEIIIYKPAYPGLGVM 140
             E+  GE V I TGA LP   DA+   E          VER   E++  +PA PG  V 
Sbjct: 93  AGEVGPGECVRIYTGAPLPPGTDAICPVEQLREGEGTSAVERGTVELL--RPARPG-DVR 149

Query: 141 KKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELK 200
            +G D   G  ++  G RL   + AL +A+G  +V V R+ +VA++STG+E+V PG  L 
Sbjct: 150 PEGGDFHAGETVMSAGLRLTPARLALAAALGHAQVPV-RRWRVALLSTGDEVVAPGQPLA 208

Query: 201 PGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISGGASGGM 260
           PGQ+YD N   L+  + E G E + LG A D   +L+E +      AD+++ SGG S G 
Sbjct: 209 PGQVYDSNRVGLAALLTEAGYEVLDLGHAPDSPAALRERL-GAAGGADLLLTSGGVSMGR 267

Query: 261 RDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFTLLVVPLLL 320
            D    ++   GE+    + ++PG P + G   G PVFGLPG P S L  F ++V P+L 
Sbjct: 268 YDFMRDLLLGEGEITFWKVKMRPGGPALCGRWGGLPVFGLPGNPVSSLVVFQVIVRPVL- 326

Query: 321 RALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGG-VAVPILKGSGAVTSFIDADGFI 379
              G     R+V A       S+  +  F    L G  V     +GSG + S  DAD  +
Sbjct: 327 --TGEPLPTRQVTAAT--PFASLADKTAFWRGVLSGDEVRDYPRQGSGVLRSLSDADALV 382

Query: 380 EIPETVESVDEGEEVEVTL 398
            +PE  +++  GE VEV L
Sbjct: 383 VVPEG-QNIAAGERVEVVL 400


>gb|AAF73075.1|AF268595_1 (AF268595) molybdenum cofactor biosynthesis protein Cnx1 [Hordeum
           vulgare]
           Length = 659
           
 Score =  180 bits (453), Expect = 2e-44
 Identities = 119/341 (34%), Positives = 180/341 (51%), Gaps = 26/341 (7%)

Query: 28  VKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIHAGE 87
           V L +ALG ++AED  +P  +PPF  +  DGYAV A D        P +  V+ E  AG+
Sbjct: 25  VPLLDALGLVLAEDARAPDPLPPFRASVKDGYAVVAAD-------GPGEYPVIAEARAGD 77

Query: 88  EPK-LELKKGETVYISTGAMLPKNADAVIQFEDVERV-----GDEIIIYKPAYP-GLGVM 140
           +   + +  G   Y++TG  +P  ADAV+Q ED E+V     G + +      P G  + 
Sbjct: 78  DALGVVVTPGTVAYVTTGGPIPDGADAVVQVEDTEQVAAAPDGSKRVRISARVPEGHDIR 137

Query: 141 KKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPG-SEL 199
             G DI K  ++++ GE +G  +  LL+ VGV  V+ +R+P +A+ STG+E+V P  + L
Sbjct: 138 SVGCDIEKDSIVLKSGENIGPAEIGLLATVGVTTVKAYRRPTIAVFSTGDELVEPATATL 197

Query: 200 KPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRV-ADIVVISGGASG 258
             GQI D N   L  A  +   + + LGIA+D  ESL E ++  +   ADI++ SGG S 
Sbjct: 198 NRGQIRDSNRAMLLAAAIQQKCKVVDLGIAKDTEESLMEHMDAALHSDADIILTSGGVSM 257

Query: 259 GMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEING----KP-----VFGLPGYPTSCLT 309
           G RDL    + ++G++    I ++PGKP    EI      KP      FGLPG P SC+ 
Sbjct: 258 GDRDLVKPCLAKMGKIHFEKIRMKPGKPLTFAEITSNDTTKPSKTALAFGLPGNPVSCMV 317

Query: 310 NFTLLVVPLLLRALG-REGKVRKVKARLKHKIFSVKGRRQF 349
            F + VVP +    G     +++V  R+ H + +   R +F
Sbjct: 318 CFNVFVVPAIRLVSGWSNPHLQRVHVRISHPLRADPHRMEF 358


>pir||H83155 molybdenum cofactor biosynthetic protein A1 PA3914 [imported] -
           Pseudomonas aeruginosa (strain PAO1)
           >gi|9950098|gb|AAG07301.1|AE004809_1 (AE004809)
           molybdenum cofactor biosynthetic protein A1 [Pseudomonas
           aeruginosa]
           Length = 407
           
 Score =  179 bits (449), Expect = 6e-44
 Identities = 124/378 (32%), Positives = 194/378 (50%), Gaps = 9/378 (2%)

Query: 8   PLERAL-EIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDT 66
           PL+ AL E++     P   E + L  ALGR++ ED+ +P+D+P +D + +DGYA+ + D 
Sbjct: 13  PLDEALAELLARAPRPPACESLALERALGRVLGEDLLAPMDLPHWDNSAMDGYALCSADL 72

Query: 67  FMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDE 126
             +  +    L V   I AG+   + L  G+   I TGA LP  AD V+  +++  V  E
Sbjct: 73  PRSGGS----LTVGARIAAGDTRGMSLPLGQAARIFTGAPLPTGADCVVP-QELCVVDGE 127

Query: 127 IIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAII 186
            +   P   G  V ++G ++ +G  ++R G+RL  ++  LL+++GV  V V R+ ++ ++
Sbjct: 128 RVQLPPVSAGQHVRRRGEELRRGAPVLRAGQRLRPQELGLLASLGVATVSVRRRLRIGLL 187

Query: 187 STGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRV 246
           S+G+E+  PG  L  GQIY+ N   +   +  LG E     +  D+  + ++ +      
Sbjct: 188 SSGDELREPGQTLLAGQIYNANRYCIGALLRGLGFEVHDEEVLADELVASRDALSLAASE 247

Query: 247 ADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTS 306
            D +V SGG S G  D     I ELGEV +  +AIQPGKP   G + GKP  GLPG P +
Sbjct: 248 WDALVTSGGVSVGEEDHLKRAIAELGEVNLWRLAIQPGKPFAFGSVAGKPWLGLPGNPAA 307

Query: 307 CLTNFTLLVVPLLLRALGREGKV-RKVKARLKHKIFSVKGRRQFLPVKLE--GGVAVPIL 363
            L    L+  P LLR  G    V R +           + RRQ+L  +L+  G V +   
Sbjct: 308 ALVTALLVARPFLLRQQGLFDVVPRPLALPAAFDWPQPRARRQYLRARLDERGRVEIHPQ 367

Query: 364 KGSGAVTSFIDADGFIEI 381
           +GS  + +   ADG   I
Sbjct: 368 QGSAMLLAASWADGLAVI 385


>pir||T46858 molybdenum cofactor biosynthesis protein A [imported] - Rhodobacter
           sphaeroides >gi|4185549|gb|AAD09121.1| (AF108766)
           molybdenum cofactor biosynthesis protein A [Rhodobacter
           sphaeroides]
           Length = 394
           
 Score =  176 bits (443), Expect = 3e-43
 Identities = 118/320 (36%), Positives = 167/320 (51%), Gaps = 10/320 (3%)

Query: 6   VVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAED 65
           ++ +E AL    +   PL  E V L EA GR++A    +  D PPFD + +DGYA+  + 
Sbjct: 1   MISVEEALARALALAAPLPVERVALGEARGRVMARPALATRDQPPFDASAMDGYALIGDP 60

Query: 66  TFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGD 125
              A+        VVGE  AG   +  L+ GE V I TGA +P+ A  V+  EDV   G 
Sbjct: 61  PAGAT------FPVVGEAAAGHGYEGALRPGEAVRIFTGAPVPEGATRVVLQEDVTAEGG 114

Query: 126 EIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAI 185
            I +   A  G  +  +G D   G  L  +  RL     ALL+A+ +  V V R+P VA+
Sbjct: 115 TIRLNAAATGGTHIRPRGQDFRTGDSLSPR--RLRPNDLALLAAMNIPEVTVTRRPSVAL 172

Query: 186 ISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVR 245
           I+TG+E+V+PG   +P QI   N  AL   V   G E   L IARD  + L+ +++    
Sbjct: 173 IATGDELVMPGEVPRPDQIVASNSFALKALVEAEGAEARLLPIARDTEDELRTVLDL-AS 231

Query: 246 VADIVVISGGASGGMRDLTASVIEELG-EVKVHGIAIQPGKPTIIGEINGKPVFGLPGYP 304
            AD++V  GGAS G  DL   V   +G E   + IA++PGKP + G + G P+ GLPG P
Sbjct: 232 DADLIVTIGGASVGDHDLVGKVAAGMGLERAFYKIAMRPGKPLMAGRLRGVPMLGLPGNP 291

Query: 305 TSCLTNFTLLVVPLLLRALG 324
            S +    L ++P+L   LG
Sbjct: 292 VSSIVCAHLFLLPMLRAMLG 311


>pir||G71966 molybdopterin biosynthesis protein - Helicobacter pylori  (strain
           J99) >gi|4154674|gb|AAD05741.1| (AE001454) MOLYBDOPTERIN
           BIOSYNTHESIS PROTEIN [Helicobacter pylori J99]
           Length = 390
           
 Score =  167 bits (419), Expect = 2e-40
 Identities = 121/410 (29%), Positives = 207/410 (49%), Gaps = 36/410 (8%)

Query: 6   VVPLERALEIVNSFTL-PLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAE 64
           ++  + AL+I ++  L PL  E V L E+ GRI+AEDI     +P F+++ +DGY  + +
Sbjct: 1   MISFKEALKIHSNIPLKPLEVEVVSLFESAGRILAEDIICVHALPKFNQSAMDGYGFKMQ 60

Query: 65  DTFMASEANPIKLKVVGEIHAGEEPK-LELKKGETVYISTGAMLPKNADAVIQFEDV-ER 122
           D          K +V+  I AG++   LE+K+ E V I TGAM+PK  + ++  E + E 
Sbjct: 61  DLGQ-------KTQVIQHIFAGDDVSALEVKENECVKIMTGAMVPKGIETIVPIECMLES 113

Query: 123 VGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPK 182
             D  +  K       + +KG + S   +LV K  RL +   AL+++ G + ++ FRK K
Sbjct: 114 HKDFALAPKDFKIHANIRQKGENASLNSVLVPKNTRLNYGHIALIASQGFKEIKAFRKLK 173

Query: 183 VAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEE 242
           +A+ S+G+E+V  G      Q+YD+N   + + +        FLG+ +DD+    +++E 
Sbjct: 174 IALFSSGDELVPLGQNALECQVYDVNSVGVFNMLKNYNTH--FLGVLKDDKNLQLKILE- 230

Query: 243 GVRVADIVVISGGASGGMRDLTASVIEELGEVKVH-GIAIQPGKPTIIGEINGKPVFGLP 301
            ++  D+++ S G S G +D     ++E   +  +  + ++PGKP  + ++N   + GLP
Sbjct: 231 -LQGYDVILSSAGVSVGDKDFFKDALKERNALFYYEKVNLKPGKPVTLAQLNQSIIIGLP 289

Query: 302 GYPTSCLTNFTLLVVPLLLR-ALGREGKVRKVKARLK----------HKIFSVKGRRQFL 350
           G P SCL    +L++PLL R +L ++ K++  KA++           H I       QF+
Sbjct: 290 GNPLSCLLVLRVLILPLLERLSLNKDFKLKPFKAQINAPLKLNNKRTHLILGNYSNHQFI 349

Query: 351 PVKLEGGVAVPILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFE 400
           P              SGA+ +    D    I E V  V    E+E+  FE
Sbjct: 350 PYNNR--------YESGAIQALAQVDSIALIDEGVGLVQ--GEIEILRFE 389


>pir||D64541 molybdopterin biosynthesis protein - Helicobacter pylori  (strain
           26695) >gi|2313255|gb|AAD07237.1| (AE000537)
           molybdopterin biosynthesis protein (moeA) [Helicobacter
           pylori 26695]
           Length = 391
           
 Score =  167 bits (418), Expect = 2e-40
 Identities = 120/410 (29%), Positives = 207/410 (50%), Gaps = 35/410 (8%)

Query: 6   VVPLERALEIVNSFTL-PLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAE 64
           ++  + AL+I +S  + PL  E + L E++GRI+AEDI     +P F+++ +DGY  + +
Sbjct: 1   MISFKEALKIHSSIPIKPLEIEVISLFESIGRILAEDIICIHALPKFNQSAMDGYGFKMQ 60

Query: 65  DTFMASEANPIKLKVVGEIHAGEEPK-LELKKGETVYISTGAMLPKNADAVIQFEDV-ER 122
           D          K +VV  I AG++   LE+K+ E V I TGAM+PK  + ++  E + E 
Sbjct: 61  DLGK-------KTQVVQRIFAGDDVSALEVKENECVKIMTGAMVPKGIETIVPIECMLES 113

Query: 123 VGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPK 182
             +  +  K       + +KG + S   +LV K  RL +   AL+++ G++ ++ FRK K
Sbjct: 114 HTNFALAPKDFKINANIRQKGENASLNSVLVPKNTRLNYGHIALIASQGLKEIKAFRKLK 173

Query: 183 VAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEE 242
           +A+ S+G+E+V  G      Q+YD+N   + + +        FLG+ +DD+    +++E 
Sbjct: 174 IALFSSGDELVPLGQNALECQVYDVNSVGIFNMLKNYNTH--FLGVLKDDKNLQLKILES 231

Query: 243 GVRVADIVVISGGASGGMRDLTASVIEELGEVKVH-GIAIQPGKPTIIGEINGKPVFGLP 301
             +  D+++ S G S G +D     ++E   +  +  + ++PGKP  +  +N   + GLP
Sbjct: 232 --QDYDVILSSAGVSVGDKDFFKDALKEKNALFYYEKVNLKPGKPVTLARLNQSMIIGLP 289

Query: 302 GYPTSCLTNFTLLVVPLLLR-ALGREGKVRKVKARLK----------HKIFSVKGRRQFL 350
           G P SCL    +L++PLL R +L ++ K++  KA++           H I       QF+
Sbjct: 290 GNPLSCLLVLRVLILPLLERLSLNKDFKLKPFKAQINAPLKLKGERAHLILGNYSNHQFI 349

Query: 351 PVKLEGGVAVPILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFE 400
           P              SGA+ +    D    I E V  V    E+E+  FE
Sbjct: 350 PYNNN-------RYDSGAIQALARVDSIALIDEGVRLVQ--GEIEILRFE 390


>pir||T44851 molybdopterin co-factor synthesis protein moeA [imported] -
           Arthrobacter nicotinovorans plasmid pAO1
           >gi|4469094|emb|CAA71780.2| (Y10817) molybdopterin
           co-factor synthesis protein [Arthrobacter
           nicotinovorans]
           Length = 430
           
 Score =  163 bits (408), Expect = 4e-39
 Identities = 105/307 (34%), Positives = 156/307 (50%), Gaps = 18/307 (5%)

Query: 22  PLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVG 81
           P   E + L +A+GR +AE I++P ++PPF  + +DGYAVR+ DT          L+V  
Sbjct: 50  PPRVERIPLMQAMGRGLAETIHAPTNLPPFTNSQMDGYAVRSRDTAGGQGG----LRVAA 105

Query: 82  EIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVG---------DEIIIYKP 132
            I AG  P   L  G    I TGA++P  ADAV+    VER           D  +    
Sbjct: 106 PIPAGAVPA-PLVGGTAAQIMTGALIPDGADAVVP---VERAVPNHFPPPGLDRTVRLPE 161

Query: 133 AYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEI 192
              G  +   G DI+ G   +  G  LG +Q  LL+A+G+  V V +K  V + +TG+E+
Sbjct: 162 IAAGTYIRSAGSDIATGECALSAGTVLGPRQLGLLAALGITEVVVNQKLTVLLATTGDEV 221

Query: 193 VLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVI 252
           + PG +L  G+IYD N   L  ++ + G   I  GI +D+  +L +L+       D++V 
Sbjct: 222 LEPGEKLALGKIYDANNTLLQSSMLQAGLNVIRAGIVKDEPGALSKLLRSHTAHVDLIVT 281

Query: 253 SGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFT 312
           SGG S G  +     + +  +V+   +AIQPG P  +G   G PV   PG P SC  +F 
Sbjct: 282 SGGVSAGAYEPVRQAMID-HDVEFSHVAIQPGGPQGVGTFEGIPVLAFPGNPVSCFVSFE 340

Query: 313 LLVVPLL 319
           + + PLL
Sbjct: 341 MFLRPLL 347


>gb|AAK40978.1| Molybdopterin biosynthesis protein (moeA-1) [Sulfolobus
           solfataricus]
           Length = 389
           
 Score =  162 bits (407), Expect = 5e-39
 Identities = 110/395 (27%), Positives = 201/395 (50%), Gaps = 12/395 (3%)

Query: 4   LKVVPLERALEIVNSFTLPLGTEE--VKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAV 61
           + ++P+E A +I+++    +   E  V++ +ALG+I  EDI +   +P    + +DGYA+
Sbjct: 1   MALIPVEEARKIISNTNFEVKRREKYVEIFQALGKIAVEDILAVKSMPERSLSAMDGYAI 60

Query: 62  RAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVE 121
           + +D          KL+VVG+++       ELK+GET Y++TG+ LP  AD+V+  E+  
Sbjct: 61  KYDDYLKYG-----KLRVVGKLYPSTSNIPELKEGETYYVTTGSPLPLYADSVVPVENSR 115

Query: 122 RVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKP 181
             G+ +I       G  + ++G DI+ G+++++KG  +      +L    +  V+V    
Sbjct: 116 LEGEYVIFKGEVKKGKNIREEGEDINIGQIIIQKGTEITPYYLGILIQQKIFHVKV-SDL 174

Query: 182 KVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIE 241
           K  + + G+EI    +  K   I  I+   +   + E  G   ++G+A+DD   + E IE
Sbjct: 175 KFTVFANGDEITSFENPQKNKIIDSISPILIK--ILEKFGSVKYMGVAKDDLNDVTEKIE 232

Query: 242 EGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLP 301
           + + ++D+++  GG+S G +D     + +LGEV   G+++   K   +G I GKP+  LP
Sbjct: 233 KSLEISDVIISVGGSSVGEKDYVKKAVNKLGEVLFDGVSVNTIKRGSVGRIQGKPILILP 292

Query: 302 GYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAVP 361
           G   S +T F    + +L   LG   K + +K+ L   I+            ++G  A P
Sbjct: 293 GQVVSAITAFHEFGLSVLSNILGTNLK-KFIKSTLVEDIYVNHSMDSVYLFNVKGNSAFP 351

Query: 362 ILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEV 396
           +  G G  +    A+GF  +   + +  +GEEVE+
Sbjct: 352 LRWGVGLYSELAKANGFAILKRGL-TYKKGEEVEL 385


>emb|CAB57627.1| (Y18930) molybdopterin biosynthesis protein [Sulfolobus
           solfataricus]
           Length = 389
           
 Score =  162 bits (407), Expect = 5e-39
 Identities = 110/395 (27%), Positives = 201/395 (50%), Gaps = 12/395 (3%)

Query: 4   LKVVPLERALEIVNSFTLPLGTEE--VKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAV 61
           + ++P+E A +I+++    +   E  V++ +ALG+I  EDI +   +P    + +DGYA+
Sbjct: 1   MALIPVEEARKIISNTNFEVKRREKYVEIFQALGKIAVEDILAVKSMPERSLSAMDGYAI 60

Query: 62  RAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVE 121
           + +D          KL+VVG+++       ELK+GET Y++TG+ LP  AD+V+  E+  
Sbjct: 61  KYDDYLKYG-----KLRVVGKLYPSTSNIPELKEGETYYVTTGSPLPLYADSVVPVENSR 115

Query: 122 RVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKP 181
             G+ +I       G  + ++G DI+ G+++++KG  +      +L    +  V+V    
Sbjct: 116 LEGEYVIFKGEVKKGKNIREEGEDINIGQIIIQKGTEITPYYLGILIQQKIFHVKV-SDL 174

Query: 182 KVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIE 241
           K  + + G+EI    +  K   I  I+   +   + E  G   ++G+A+DD   + E IE
Sbjct: 175 KFTVFANGDEITSFENPQKNKIIDSISPILIK--ILEKFGSVKYMGVAKDDLNDVTEKIE 232

Query: 242 EGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLP 301
           + + ++D+++  GG+S G +D     + +LGEV   G+++   K   +G I GKP+  LP
Sbjct: 233 KSLEISDVIISVGGSSVGEKDYVKKAVNKLGEVLFDGVSVNTIKRGSVGRIQGKPILILP 292

Query: 302 GYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAVP 361
           G   S +T F    + +L   LG   K + +K+ L   I+            ++G  A P
Sbjct: 293 GQVVSAITAFHEFGLSVLSNILGTNLK-KFIKSTLVEDIYVNHSMDSVYLFNVKGNSAFP 351

Query: 362 ILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEV 396
           +  G G  +    A+GF  +   + +  +GEEVE+
Sbjct: 352 LRWGVGLYSELAKANGFAILKRGL-TYKKGEEVEL 385


>emb|CAA04211.1| (AJ000662) MoeA protein [Wolinella succinogenes]
           Length = 410
           
 Score =  160 bits (400), Expect = 3e-38
 Identities = 112/395 (28%), Positives = 187/395 (46%), Gaps = 15/395 (3%)

Query: 9   LERALEIVNSFTLPLG-TEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTF 67
           L +A+ I+     P+       L +  G+I+A+D++    +P FD + +DGYAVR  D  
Sbjct: 7   LRKAISIMLEHANPIHRVHYTHLFDLTGKILAQDLFCQKALPAFDNSGMDGYAVRLADLG 66

Query: 68  MASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEI 127
                   K  ++G I AGE   + L  G    + TGA +P    AVI FE+     D  
Sbjct: 67  Q-------KTPILGTILAGESCSVGLHDGACYKVMTGAPIPLGTQAVIPFENATLKDDST 119

Query: 128 IIYKPAYP-GLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAII 186
           ++    +  G  +   G ++  G  L++KGERL     ALL++ G   +  +   ++ + 
Sbjct: 120 VLLPTDFKEGANIKIAGEELQVGAPLLQKGERLTHHHVALLASQGYSVLPTYAPLRIGVY 179

Query: 187 STGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRV 246
           S+GNE++ P    +  QIY+ N   L   +   G    +LG+  D  E ++E I  G   
Sbjct: 180 SSGNELIEPWESAQSHQIYNSNASMLFSTLQNFGWRADYLGVLPDCLEGMREAIR-GFDA 238

Query: 247 ADIVVISGGASGGMRDLTASVIEELGEVKV-HGIAIQPGKPTIIGEINGKPVFGLPGYPT 305
            D+++ +GG S G  D     +EE G   + HGI ++PG+PT++G +    +  LPG P 
Sbjct: 239 YDVILTTGGVSQGEADFMERSLEEAGMTTLFHGIEVKPGRPTMMGILGKTTLLCLPGNPL 298

Query: 306 SCLTNFTLLVVPLLLRALG-REGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAVPILK 364
           S   N   L +P+L +  G R   +  V A  K ++     R   +  +L  G      +
Sbjct: 299 SASINLHFLGIPMLKKMQGERRYHLEFVYAPNKERLILKGNRANMVLGRLHEGCFKATQE 358

Query: 365 ---GSGAVTSFIDADGFIEIPETVESVDEGEEVEV 396
              GSG +T    ++  I   + VE+++EG  ++V
Sbjct: 359 GKYGSGMLTPLTTSNAIIFCDKGVENLEEGALIKV 393


>sp|Q56207|MOEA_SYNP7 MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|1480150|emb|CAA67944.1|
           (X99625) moeA [Synechococcus sp.]
           Length = 403
           
 Score =  159 bits (397), Expect = 7e-38
 Identities = 121/389 (31%), Positives = 198/389 (50%), Gaps = 20/389 (5%)

Query: 21  LPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVV 80
           LPL  E V L E   R++A+D+ +P D+P +D + +DG+A+R++D   AS   P++L VV
Sbjct: 19  LPLAIERVPLLETGDRLLAKDLAAPCDLPHWDNSAMDGFALRSQDVAAASPDRPVRLPVV 78

Query: 81  GEIHAGEEPKLELK-KGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAYPGLGV 139
           G + AGE+P L     G    + TGA +P   D +++ EDV +  + I +  P   G  +
Sbjct: 79  GRVMAGEQPPLLANPTGVACAVMTGAPIPAGFDVIVKVEDVVQEENAIAVSTPIPAGQFI 138

Query: 140 MKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSE- 198
            ++G D+ +G  L+ KG+RL      L +AVG+  + V+ K  V +ISTG E+V P S+ 
Sbjct: 139 RRQGEDLRQGSPLLAKGQRLTPMALMLAAAVGMGELPVWSKLPVGLISTGTEVV-PWSQP 197

Query: 199 -LKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIE----EGVRVADIVVIS 253
            L+ GQI + +   L + +  LG E   +    DD E    + +    +GVR   +++ +
Sbjct: 198 TLELGQIRNSSQPFLIEQLQRLGCEVRAIAHVPDDPEQFAAIAQQFWSQGVR---LLLTT 254

Query: 254 GGASGGMRDLTASVIEELG-EVKVHGIAIQPGKPTI--IGEINGKPVFGLPGYPTSCLTN 310
           G  S G+ D   + +E LG +   H +AI+PGKP +  I   +   V   PG P S    
Sbjct: 255 GAVSMGVADFVPAALERLGCQTIFHKVAIRPGKPLLFAIAPEHQGLVLACPGNPVSTTVT 314

Query: 311 FTLLVVPLLLRALGREGKVRK-VKARLKHKIFSVKGRRQFLPVKL--EGGVAVPILKGSG 367
               + PLL+       +VR  +   L   +   +G + F   +L  EG V V   + S 
Sbjct: 315 AEFFLKPLLMAC---RNEVRSPLWLPLAESVRKPEGLQCFWRSRLTPEGKVWVDPQQSSA 371

Query: 368 AVTSFIDADGFIEIPETVESVDEGEEVEV 396
           A+ S +++  +  +P   + +  G  VEV
Sbjct: 372 ALKSLVESTHWAILPAGQDFLAAGTPVEV 400


>pir||A81359 probable molybdopterin biosynthesis protein Cj0857c [imported] -
           Campylobacter jejuni (strain NCTC 11168)
           >gi|6968303|emb|CAB73122.1| (AL139076) putative
           molybdopterin biosynthesis protein [Campylobacter
           jejuni]
           Length = 386
           
 Score =  156 bits (390), Expect = 5e-37
 Identities = 109/374 (29%), Positives = 180/374 (47%), Gaps = 17/374 (4%)

Query: 25  TEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIH 84
           +E + L +A  RI+A+D+Y+  ++P FD A +DGYA    D   A       L++ G I 
Sbjct: 21  SELISLEKAKDRILAKDLYARKNLPSFDNAALDGYAFNYTDINEA-------LEIKGTIF 73

Query: 85  AGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAYPGLGVMKKGV 144
           AG++    + K E   I TGA +PKNAD ++  ED     +++II K          KG 
Sbjct: 74  AGDKNFYTVAKNECYKIMTGAKMPKNADTILMLEDECIEENKLIIKKVPKQYNAYRYKGE 133

Query: 145 DISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELKPGQI 204
           ++ KG +L++KG +L  K  ALL++ G+ ++ V RK ++ I S+GNE+  P  E     I
Sbjct: 134 ELKKGEILLQKGTKLNDKHIALLASQGLYKIEVIRKIRIGIFSSGNELKEPWQECDEESI 193

Query: 205 YDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISGGASGGMRDLT 264
           Y+ N   L   +        +LGI +DD +S KE +E      D+++ SGGAS G  D  
Sbjct: 194 YNANALPLLTMLQNAS----YLGIIKDDFKSTKEALEN--TNFDLLITSGGASVGEADFM 247

Query: 265 ASVIEELGEVKV-HGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFTLLVVPLLLRAL 323
              ++ELG   +  G+  +P +PT +       V  LPG P +   +  +    ++    
Sbjct: 248 EKALDELGFTPLFKGLKARPARPTKLYRKGENFVLILPGNPMAAYLSCFIFAKKIINLLS 307

Query: 324 GREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAVPILK---GSGAVTSFIDADGFIE 380
           G          ++   +    GR   +   LE G+  P  +   GSG +   I ++  + 
Sbjct: 308 GNLDNPLTFYGKMGMDLKLKSGRNNLILGNLEKGIFTPFNENKFGSGMILPLIKSEFLLI 367

Query: 381 IPETVESVDEGEEV 394
             E    + +G+E+
Sbjct: 368 SEENTGELKKGDEI 381


>emb|CAB57390.1| (AJ238348) MoeA protein [Rhodobacter capsulatus]
           Length = 459
           
 Score =  151 bits (377), Expect = 2e-35
 Identities = 121/416 (29%), Positives = 190/416 (45%), Gaps = 37/416 (8%)

Query: 6   VVPLERALEIVNSFTLPLG-TEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAE 64
           ++ L+ A  +      P+G +E + L++A GR  A  + + I +P   R+ +DG+A+R  
Sbjct: 56  MLDLDSARRLACGLVAPIGDSETLDLAQAAGRTSATSLRAEIALPRAARSAMDGFALRTA 115

Query: 65  DTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVG 124
           D   A     + L V G + AG +    L  G  + I TGA +P  ADAV+  E+V   G
Sbjct: 116 DLAAA-----LTLPVAGTVAAGMQAP-PLPDGAALRIFTGAQIPAGADAVVPVEEVTETG 169

Query: 125 DEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVA 184
            E+ +     PG  +   G +   G LL+R+G R+      LL++ GV  V V R+P++A
Sbjct: 170 AEVQLTAAPAPGSHIRAVGSEQPLGGLLLRRGTRIRAHHIGLLASNGVAEVAVVRRPRLA 229

Query: 185 IISTGNEIVLPGSE-LKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEG 243
           I+STG+E+  PG+E      + D+N   L       G E    GI  DD E+        
Sbjct: 230 ILSTGDELHRPGAEAASRDTMPDVNRPMLIALAQGAGAEVDDHGILPDDAEATVAKFASL 289

Query: 244 VRVADIVVISGGASGGMRD-LTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPG 302
               D++V +G  S G RD L  ++I   G++    +A++PGKP + G +    V GLPG
Sbjct: 290 QGRYDLIVTTGAVSMGGRDHLRPALIAAGGQIDGWKVALKPGKPVMFGRLGNAAVTGLPG 349

Query: 303 YPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQF-----------LP 351
            P S +  FTL V            ++ ++K  +   +F   GR  F            P
Sbjct: 350 NPFSAMVGFTLFV----------SAQIARLKGAVPAPLFHCAGRAGFDWTRKPDRAEIFP 399

Query: 352 VKLEGGV--AVPILKGSGAVTS-----FIDADGFIEIPETVESVDEGEEVEVTLFE 400
           ++L       +P++   G  TS       +ADG   +P     V  G  +    FE
Sbjct: 400 IRLGNREIDGLPVVHRLGEGTSATLFPLAEADGLGFVPAETARVSVGTPICWQTFE 455


>pir||B81299 probable molybdopterin biosynthesis protein Cj1519 [imported] -
           Campylobacter jejuni (strain NCTC 11168)
           >gi|6968943|emb|CAB73939.1| (AL139078) putative
           molybdopterin biosynthesis protein [Campylobacter
           jejuni]
           Length = 396
           
 Score =  148 bits (371), Expect = 8e-35
 Identities = 91/295 (30%), Positives = 156/295 (52%), Gaps = 9/295 (3%)

Query: 26  EEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIHA 85
           E++ L+E LGRI+A+DI +P + P F  + +DGYA++ ED     +  P  LK++G   A
Sbjct: 23  EKIALTECLGRILAQDIKAPKNQPEFPTSAMDGYAIKFED-----QDKP--LKILGLTPA 75

Query: 86  GEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAYPGLGVMKKGVD 145
           G  P+  ++ G  V   TG+++ + +D ++  E++    + + I K       V   G +
Sbjct: 76  GTMPQFSVQNGTCVKTFTGSLMSEGSDTLVPVENIRIENNTLFIEKKVPQAFAVRAVGEN 135

Query: 146 ISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELK-PGQI 204
             K  +L++KG RL + + ALL+ +G   + VF KP V ++S+G+EI   G  L+ P QI
Sbjct: 136 YKKDEILLKKGTRLNYSEIALLAELGFFHISVFIKPIVGVLSSGSEIKDLGEALENPAQI 195

Query: 205 YDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISGGASGGMRDLT 264
              N  A+++    L  +     + +DD ++    +E  ++  DI+V +GG S G  D  
Sbjct: 196 RSSNHIAIANLAKNLNCDTRVFPLLKDDEKATFSTLESALQSCDILVTTGGVSMGDFDFL 255

Query: 265 ASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFTLLVVPLL 319
              I+E  E+ +    I+PG+   I + N K +  LPG+P S +  F L    +L
Sbjct: 256 KKAIKEY-EIIIDKADIKPGRHIKIAKANEKFIIALPGFPYSAMVMFNLYTREIL 309


>emb|CAB65851.1| (AL050231) alternatively spliced form [Drosophila melanogaster]
           Length = 674
           
 Score =  142 bits (355), Expect = 6e-33
 Identities = 120/395 (30%), Positives = 197/395 (49%), Gaps = 38/395 (9%)

Query: 6   VVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAED 65
           ++P++  L I+ +         V+ +  L +I+ E + +P++IPPF  +  DGYA+++  
Sbjct: 271 MLPVQEVLSIIFN--------TVQKTANLNKILLE-MNAPVNIPPFRASIKDGYAMKSTG 321

Query: 66  TFMASEANPIKLKVVGEIHAGEEPK-LELKKGETVYISTGAMLPKNADAVIQFED----- 119
            F  ++      +V+G I AG+ P  L L + E   I+TGA LP  AD V+Q ED     
Sbjct: 322 -FSGTK------RVLGCIAAGDSPNSLPLAEDECYKINTGAPLPLEADCVVQVEDTKLLQ 374

Query: 120 VERVGDEIIIYKPAYP--GLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRV 177
           +++ G E ++     P  GL V   G D+S    +    +       +LL++VG   +  
Sbjct: 375 LDKNGQESLVDILVEPQAGLDVRPVGYDLSTNDRIFPALDPSPVVVKSLLASVGNRLI-- 432

Query: 178 FRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLK 237
             KPKVAI+STG+E+  P ++L PG+I+D N   L++ +   G   +   +  D  +  K
Sbjct: 433 LSKPKVAIVSTGSELCSPRNQLTPGKIFDSNTTMLTELLVYFGFNCMHTCVLSDSFQRTK 492

Query: 238 ELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVH--GIAIQPGKPTIIGEINGK 295
           E + E   V D V+ SGG S G +D   SV+E+L + ++H   + I+PGKP        K
Sbjct: 493 ESLLELFEVVDFVICSGGVSMGDKDFVKSVLEDL-QFRIHCGRVNIKPGKPMTFASRKDK 551

Query: 296 PVFGLPGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKI---FSVKGRRQFLPV 352
             FGLPG P S    F L  +P +  A G + + +   + L  K+   FS+  R +F+  
Sbjct: 552 YFFGLPGNPVSAFVTFHLFALPAIRFAAGWD-RCKCSLSVLNVKLLNDFSLDSRPEFVRA 610

Query: 353 KL--EGGVAVPILKG---SGAVTSFIDADGFIEIP 382
            +  + G     + G   S  + S + AD  I +P
Sbjct: 611 SVISKSGELYASVNGNQISSRLQSIVGADVLINLP 645


>emb|CAB65852.1| (AL050231) EG:BACR37P7.3 [Drosophila melanogaster]
           >gi|7290021|gb|AAF45488.1| (AE003417) cin gene product
           [Drosophila melanogaster]
           Length = 601
           
 Score =  142 bits (355), Expect = 6e-33
 Identities = 120/395 (30%), Positives = 197/395 (49%), Gaps = 38/395 (9%)

Query: 6   VVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAED 65
           ++P++  L I+ +         V+ +  L +I+ E + +P++IPPF  +  DGYA+++  
Sbjct: 198 MLPVQEVLSIIFN--------TVQKTANLNKILLE-MNAPVNIPPFRASIKDGYAMKSTG 248

Query: 66  TFMASEANPIKLKVVGEIHAGEEPK-LELKKGETVYISTGAMLPKNADAVIQFED----- 119
            F  ++      +V+G I AG+ P  L L + E   I+TGA LP  AD V+Q ED     
Sbjct: 249 -FSGTK------RVLGCIAAGDSPNSLPLAEDECYKINTGAPLPLEADCVVQVEDTKLLQ 301

Query: 120 VERVGDEIIIYKPAYP--GLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRV 177
           +++ G E ++     P  GL V   G D+S    +    +       +LL++VG   +  
Sbjct: 302 LDKNGQESLVDILVEPQAGLDVRPVGYDLSTNDRIFPALDPSPVVVKSLLASVGNRLI-- 359

Query: 178 FRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLK 237
             KPKVAI+STG+E+  P ++L PG+I+D N   L++ +   G   +   +  D  +  K
Sbjct: 360 LSKPKVAIVSTGSELCSPRNQLTPGKIFDSNTTMLTELLVYFGFNCMHTCVLSDSFQRTK 419

Query: 238 ELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVH--GIAIQPGKPTIIGEINGK 295
           E + E   V D V+ SGG S G +D   SV+E+L + ++H   + I+PGKP        K
Sbjct: 420 ESLLELFEVVDFVICSGGVSMGDKDFVKSVLEDL-QFRIHCGRVNIKPGKPMTFASRKDK 478

Query: 296 PVFGLPGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKI---FSVKGRRQFLPV 352
             FGLPG P S    F L  +P +  A G + + +   + L  K+   FS+  R +F+  
Sbjct: 479 YFFGLPGNPVSAFVTFHLFALPAIRFAAGWD-RCKCSLSVLNVKLLNDFSLDSRPEFVRA 537

Query: 353 KL--EGGVAVPILKG---SGAVTSFIDADGFIEIP 382
            +  + G     + G   S  + S + AD  I +P
Sbjct: 538 SVISKSGELYASVNGNQISSRLQSIVGADVLINLP 572


>sp|P39205|CIN_DROME MOLYBDENUM COFACTOR SYNTHESIS PROTEIN CINNAMON
           >gi|1079093|pir||S47896 probable molybdopterin
           biosynthesis protein cinnamon - fruit fly (Drosophila
           melanogaster) >gi|505312|gb|AAA65877.1| (L19876)
           molybdenum cofactor [Drosophila melanogaster]
           Length = 601
           
 Score =  142 bits (354), Expect = 8e-33
 Identities = 120/395 (30%), Positives = 197/395 (49%), Gaps = 38/395 (9%)

Query: 6   VVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAED 65
           ++P++  L I+ +         V+ +  L +I+ E + +P++IPPF  +  DGYA+++  
Sbjct: 198 MLPVQEVLSIIFN--------TVQKTANLNKILLE-MNAPVNIPPFRASIKDGYAMKSTG 248

Query: 66  TFMASEANPIKLKVVGEIHAGEEPK-LELKKGETVYISTGAMLPKNADAVIQFED----- 119
            F  ++      +V+G I AG+ P  L L + E   I+TGA LP  AD V+Q ED     
Sbjct: 249 -FSGTK------RVLGCIAAGDSPNSLPLAEDECYKINTGAPLPLEADCVVQVEDTKLLQ 301

Query: 120 VERVGDEIIIYKPAYP--GLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRV 177
           +++ G E ++     P  GL V   G D+S    +    +       +LL++VG   +  
Sbjct: 302 LDKNGQESLVDILVEPQAGLDVRPVGYDLSTNDRIFPALDPSPVVVKSLLASVGNRLI-- 359

Query: 178 FRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLK 237
             KPKVAI+STG+E+  P ++L PG+I+D N   L++ +   G   +   +  D  +  K
Sbjct: 360 LSKPKVAIVSTGSELCSPRNQLTPGKIFDSNTTMLTELLVYFGFNCMHTCVLSDTFQRTK 419

Query: 238 ELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVH--GIAIQPGKPTIIGEINGK 295
           E + E   V D V+ SGG S G +D   SV+E+L + ++H   + I+PGKP        K
Sbjct: 420 ESLLELFEVVDFVICSGGVSMGDKDFVKSVLEDL-QFRIHCGRVNIKPGKPMTFASRKDK 478

Query: 296 PVFGLPGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKI---FSVKGRRQFLPV 352
             FGLPG P S    F L  +P +  A G + + +   + L  K+   FS+  R +F+  
Sbjct: 479 YFFGLPGNPVSAFVTFHLFALPAIRFAAGWD-RCKCSLSVLNVKLLNDFSLDSRPEFVRA 537

Query: 353 KL--EGGVAVPILKG---SGAVTSFIDADGFIEIP 382
            +  + G     + G   S  + S + AD  I +P
Sbjct: 538 SVISKSGELYASVNGNQISSRLQSIVGADVLINLP 572


>sp|Q55368|MOEA_SYNY3 MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|7470744|pir||S75715
           molybdopterin biosynthesis protein moeA - Synechocystis
           sp.  (strain PCC 6803) >gi|1001210|dbj|BAA10450.1|
           (D64003) molybdopterin biosynthesis MoeA [Synechocystis
           sp.]
           Length = 390
           
 Score =  142 bits (354), Expect = 8e-33
 Identities = 112/401 (27%), Positives = 183/401 (44%), Gaps = 32/401 (7%)

Query: 6   VVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAED 65
           ++ +  A+EI+ +     G   + +  + GR++AE I +  D PP DR  +DG A+   +
Sbjct: 1   MISVAAAVEIIQAHWPNFGDTTMDVDGSYGRVLAESIEADRDYPPGDRVMMDGVALAWSE 60

Query: 66  TFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGD 125
                       K++G + AG        +   + + TGA+LP+N D VI +E+V    +
Sbjct: 61  YHQGRR----HFKLLGTVAAGTPQSSLPDQTGCLEVMTGALLPQNCDLVIPYEEVAIADN 116

Query: 126 EIIIYKPAY--PGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKV 183
           ++ I  P    PG  V  K  D   G++++    +L      ++++ G  +VRV +KP++
Sbjct: 117 QVKIINPRQREPGEFVHPKASDCRAGKVILESSSKLNGPAWNIITSFGKTKVRVKQKPRI 176

Query: 184 AIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEG 243
            IISTG+E+V    + K  Q+   N   L  ++   G + + L    DD+E +    ++ 
Sbjct: 177 QIISTGDELVEITQKPKIHQLRRSNIYGLQVSLQSRGFQNVNLTHLADDKEVIIRHYQKA 236

Query: 244 VRVADIVVISGGASGGMRDLTASVIEELGEVK-VHGIAIQPGKPTIIG--EINGKPVFGL 300
                +++ SGG S G  D    V  +LG  K +HG+A +PGKP   G    +   + GL
Sbjct: 237 KLEYRVLIYSGGISKGKFDYLPEVWSQLGVTKYIHGVAQKPGKPMYFGIDHRSKTVIIGL 296

Query: 301 PGYPTS---CLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGG 357
           PG P S   CL  + L   P              + A+L       K    FLPVKL   
Sbjct: 297 PGNPISSLVCLHRYFLDSAP--------------IYAQLTTDFTFKKDLTYFLPVKLSHT 342

Query: 358 VAVPI------LKGSGAVTSFIDADGFIEIPETVESVDEGE 392
               I      +K SG   +   +DGF+E+P+   S   GE
Sbjct: 343 PQAVIKAEPLPVKNSGEFIALAGSDGFLELPQHQASFQAGE 383


>pir||T20638 hypothetical protein T06H11.4 - Caenorhabditis elegans
           >gi|3875564|emb|CAA90060.1| (Z49887) contains similarity
           to Pfam domain: PF00994 (Molybdenum cofactor
           biosynthesis protein), Score=324.9, E-value=3.1e-94,
           N=1~cDNA EST yk255f8.5 comes from this gene~cDNA EST
           yk255f8.3 comes from this gene~cDNA EST yk561c5.3 comes
           from this gene~c> >gi|3879587|emb|CAA90069.1| (Z49889)
           contains similarity to Pfam domain: PF00994 (Molybdenum
           cofactor biosynthesis protein), Score=324.9,
           E-value=3.1e-94, N=1~cDNA EST yk255f8.5 comes from this
           gene~cDNA EST yk255f8.3 comes from this gene~cDNA EST
           yk561c5.3 comes from this gene~c>
           Length = 442
           
 Score =  131 bits (327), Expect = 1e-29
 Identities = 107/344 (31%), Positives = 165/344 (47%), Gaps = 31/344 (9%)

Query: 21  LPLGTEEVKLS-EALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKV 79
           +P   E +++   ALGR+VAE++ S  D+PP   +T DGYAV A D            K+
Sbjct: 30  IPRIVESIQVDWSALGRVVAEEVKSSEDMPPVAASTKDGYAVIAHDGIGLK-------KM 82

Query: 80  VGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGD-------EIIIYKP 132
           VG   AG   +  ++ G+ V ISTG ++P+ ADAVI  E  E V         EII  + 
Sbjct: 83  VGVSLAGNIYQGAVEIGKCVRISTGGIIPEGADAVIMREYTELVRQDQQSEETEIICKQA 142

Query: 133 AYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEI 192
              G  +   G D+    ++V    ++G  +  +L+A G+  ++V++KP V +ISTG+E+
Sbjct: 143 VQVGENIRLPGSDVRSSDVIVPFEAQIGSAEFGILNAFGIRTIKVYKKPVVTVISTGSEV 202

Query: 193 -------VLPGSELKP-GQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGV 244
                  V P  E  P G + D N   L     E G   I  G   DD+E L + + E +
Sbjct: 203 GVIFLVLVSPMVENVPLGMVRDSNAPQLVALFKEHGFNVIDGGRVVDDKEGLDKKLTECL 262

Query: 245 RVADIVVISGGASGGMRDLTASVIEELG-EVKVHGIAIQPGKPTII------GEINGKPV 297
             +D++V +GG S G +D   + +  LG +++   ++++PG P  +       E   K V
Sbjct: 263 EHSDVIVTTGGVSMGEQDYMKNALLHLGFKIEFGRVSMKPGLPCTVATRESASERKLKVV 322

Query: 298 FGLPGYPTSCLTNFTLLVVPLLLRALG-REGKVRKVKARLKHKI 340
             LPG P S      L  VPL+    G R     K+  R+   I
Sbjct: 323 LALPGNPASAWVCSHLFAVPLIRDMSGYRRINHTKINVRIAQDI 366


>pir||H72739 probable molybdopterin biosynthesis moeA protein APE0450 -
           Aeropyrum pernix (strain K1) >gi|5104096|dbj|BAA79412.1|
           (AP000059) 577aa long hypothetical molybdopterin
           biosynthesis moeA protein [Aeropyrum pernix]
           Length = 577
           
 Score =  126 bits (313), Expect = 5e-28
 Identities = 117/387 (30%), Positives = 190/387 (48%), Gaps = 24/387 (6%)

Query: 26  EEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIHA 85
           E + L  A+GR +A    +    PP+ R  +DG AV +      S      L+V   +  
Sbjct: 40  ESLGLPAAIGRPLARKAVARGCYPPYPRVNLDGCAVDSSRVSRGSV-----LRVTARLRP 94

Query: 86  GEEP-KLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAYPG--LGVMKK 142
           G EP +L  ++G  V++ TGA LP  ADAV+  E+++ +G+ ++  + A P   +GV   
Sbjct: 95  GMEPVELVDREGGCVWVDTGAPLPVGADAVVPLEELDMLGEGVVRLE-AEPRRWMGVADP 153

Query: 143 GVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELKPG 202
             D   G +++ +GE +  +  A L++ GV  V    + +  + S G+E+       + G
Sbjct: 154 CSDAMDGSVVLGEGEVVTPEAVASLASAGVHDVEAGSRLRACVASVGDELRSLEECREGG 213

Query: 203 QIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVA-DIVVISGGASGGMR 261
            + + N       +     E + LGI  D  E+L  L          I+V SGG+S G+ 
Sbjct: 214 GVCETNRLLARSRLEAAEVEVVDLGIHPDRPETLSSLAAAARGSGCHILVTSGGSSVGLS 273

Query: 262 DLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFTLLVVPLLLR 321
           D   +  E+   + V G+AI+PG+PT +  ++G PV+ LPG P S  +   L ++P L  
Sbjct: 274 DYALAGPED---IVVRGLAIRPGRPTTLSIVDGIPVYSLPGNPRSAGSAIDLFLLPSLAA 330

Query: 322 A-LGREGKVRKVKARLKHKIFSVK-GRR-QFLPVKLE--GG--VAVPILKGSGAVTSFID 374
           A L     V  ++A L   +  VK GRR  ++PV     GG   AVP+   S    S+  
Sbjct: 331 AGLPVATVVPGMRAVL---LAGVKPGRRLSYIPVAAVYCGGRLYAVPVSTESYMTVSWAA 387

Query: 375 ADGFIEIPETVESVDEGEEVEVTLFEG 401
           ADG+I + E  ++++ GEE  VT+  G
Sbjct: 388 ADGYIAV-EPGKALEPGEEASVTIVRG 413


>pir||F72773 probable molybdopterin biosynthesis protein APE0177 - Aeropyrum
           pernix (strain K1) >gi|5103567|dbj|BAA79088.1|
           (AP000058) 386aa long hypothetical molybdopterin
           biosynthesis protein [Aeropyrum pernix]
           Length = 386
           
 Score =  100 bits (247), Expect = 3e-20
 Identities = 81/280 (28%), Positives = 133/280 (46%), Gaps = 16/280 (5%)

Query: 23  LGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGE 82
           L TE +  S+++GRI+AED+ SP D P    A +DGYAV   D+  A     ++LK  G 
Sbjct: 25  LHTEIIPSSQSVGRILAEDLESPNDTPEEPLAAMDGYAV---DSTSAKPGARLRLKDRGP 81

Query: 83  IHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAYPGLGVMKK 142
           + +GE           V + TG  LP  ADAV++ E        I +         V + 
Sbjct: 82  VASGE----------AVPVDTGDPLPPGADAVVRREAARVEDGYIYVSAGVSKWENVFRP 131

Query: 143 GVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELKPG 202
           G  +++G  L  +G+ +     AL+   GV+ V+V+R   + ++  G+E++ P +    G
Sbjct: 132 GEFVARGSRLASRGDVISPYLAALIMQAGVKSVKVYRIKSI-VMPVGSELLHPETMTGDG 190

Query: 203 QIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISGGASGGMRD 262
            + D  G  ++  +     E   +    D RE L+E I   +  ADI+V  GG+S G RD
Sbjct: 191 SL-DYIGPMVTGLLRGWS-EPRLVPPVPDGREELEEAINRALDEADILVTIGGSSVGRRD 248

Query: 263 LTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPG 302
              +++  +G++ V G      K   +  +  + V  LPG
Sbjct: 249 SLKALVASMGQLVVPGFGASVVKRGGLAVVRNRIVTMLPG 288


>pir||T36508 probable molybdenum cofactor biosynthesis protein - Streptomyces
           coelicolor >gi|5457262|emb|CAB46950.1| (AL096822)
           putative molybdenum cofactor biosynthesis protein
           [Streptomyces coelicolor A3(2)]
           Length = 465
           
 Score = 97.9 bits (240), Expect = 2e-19
 Identities = 94/375 (25%), Positives = 157/375 (41%), Gaps = 23/375 (6%)

Query: 28  VKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIHAGE 87
           V L  ALG  +A  + +  D+P FD + +DG+AV     +   +           + AG 
Sbjct: 93  VPLDAALGLTLAAPLAALTDLPSFDTSAMDGWAVAGPGPWAVRDEG---------VLAGH 143

Query: 88  EPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDE---IIIYKPAYPGLGVMKKGV 144
                L  GE V I+TGA +P +  AV++ E      DE   +   +    G  +  +G 
Sbjct: 144 AAPAPLIDGEAVRIATGARIPPDTTAVLRTEHGR--SDERGRLHPTREVVHGQDIRPRGQ 201

Query: 145 DISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELKPGQI 204
           +   G  L+  G         L +A G + +    +P+V ++  G+E++  G     G I
Sbjct: 202 ECRSGDQLLPVGTLATPAVLGLAAAAGYDTLTAVPRPRVDVLVLGDELLTQGLP-HDGLI 260

Query: 205 YDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISGGASGGMRDLT 264
            D  G  L   +  LG E   +    DD ++L   +      AD++V +GG + G  D  
Sbjct: 261 RDALGPMLPPWLRALGAEVRTVRRIGDDAKALHRAVT--TSEADLIVTTGGTAAGPVDHV 318

Query: 265 ASVIEELG-EVKVHGIAIQPGKPTIIGEI-NGKPVFGLPGYPTSCLTNFTLLVVPLLLRA 322
              +  +G E+ V G+  +PG P ++  + + + + GLPG P + ++    L  P LLR 
Sbjct: 319 HPTLRRIGAELLVDGVKARPGHPMLLARLKDDQHLVGLPGNPLAAVSGLLTLAEP-LLRT 377

Query: 323 LGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAVPI-LKGSGAVTSFIDADGFIEI 381
           L            L+  +       + +PV L G  AVP+   G   +     AD    +
Sbjct: 378 LAARPAPEPYTLPLRDAVHGHPHDTRLVPVVLRGEGAVPLRYNGPAMLRGIAAADALAVV 437

Query: 382 PETVESVDEGEEVEV 396
           P        G+E E+
Sbjct: 438 PP--GGARSGQEAEL 450


>pir||T42407 gephyrin homolog - Caenorhabditis elegans
           >gi|2811220|gb|AAB97841.1| (AF042069) LIN-46
           [Caenorhabditis elegans] >gi|2811222|gb|AAB97842.1|
           (AF042070) LIN-46 [Caenorhabditis elegans]
           Length = 391
           
 Score = 93.2 bits (228), Expect = 5e-18
 Identities = 89/333 (26%), Positives = 144/333 (42%), Gaps = 36/333 (10%)

Query: 35  GRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIHAGEEPKLELK 94
           GRI+AEDI +  DIP    + VDG+A+              K ++VG   A      EL 
Sbjct: 41  GRILAEDIITEYDIPAQRTSIVDGFAIIVNQL-------GTKREIVGLSTAVTPYNAELI 93

Query: 95  KGETVYISTGAMLPKNADAVIQFEDVERVGDE--IIIYKPAYPGLGVMKKGVDISKGRLL 152
             E V I+ G ++P  AD V+  E+V  + +E  I + +    G  + + G +   G +L
Sbjct: 94  SNECVRITIGGVVPDGADTVVPIENVALLKEEKCIEVLRKPKEGDNIREVGSEAKTGEIL 153

Query: 153 VRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELKPGQIY-DINGRA 211
           ++ G  L      LL A+G+ +V +++KP+V ++S        GS+L   ++Y   N   
Sbjct: 154 LKDGHHLDTMSITLLHALGISQVEIYKKPRVCVLSI-------GSDLNSNKMYGSFNRSQ 206

Query: 212 LSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISGGASGGMRDLTASVIEEL 271
           L +     G   I  G + +    ++E I      A ++V  GG         A VI E+
Sbjct: 207 LLELFQSQGFTAIDAGSSTEHITEVEEKIRTAASFACVLVTVGG---------AQVIREV 257

Query: 272 GEV-----KVHGIAIQPGKPTI-IGEINGKPVF--GLPGYPTSCLTNFTLLVVPLLLRAL 323
            +      ++  +   PG  T+  G+I+  PV     P Y  S      L V P+L    
Sbjct: 258 AKTLKFKFEIQDVDSTPGNFTVSTGKIDETPVVLSIFPEYHVSSWIGANLFVSPILRAME 317

Query: 324 GREGKV-RKVKARLKHKIFSVKGRRQFLPVKLE 355
           G+  +   + KA L   I S     +FL  + E
Sbjct: 318 GQNSETSHRFKAELTQPI-SKTSETRFLRARSE 349


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.317    0.141    0.392 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 148003449
Number of Sequences: 2977
Number of extensions: 6590256
Number of successful extensions: 18794
Number of sequences better than 1.0e-10: 63
Number of HSP's better than  0.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 18562
Number of HSP's gapped (non-prelim): 69
length of query: 402
length of database: 189,106,746
effective HSP length: 57
effective length of query: 345
effective length of database: 154,992,987
effective search space: 53472580515
effective search space used: 53472580515
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 166 (69.1 bits)