BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1436 (moeA-1) DE:molybdenum cofactor biosynthesis protein (moeA-1) (402 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||A75054 molybdenum cofactor biosynthesis protein (moea-1) PA... 786 0.0 pir||B71173 probable molybdopterin biosynthesis moea protein - P... 686 0.0 gi|11498536 molybdenum cofactor biosynthesis protein (moeA-1) [A... 374 e-102 pir||G69000 molybdenum cofactor biosynthesis protein MoeA - Meth... 342 5e-93 sp|Q58296|Y886_METJA PUTATIVE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN... 339 4e-92 gi|11498535 molybdenum cofactor biosynthesis protein (moeA-2) [A... 288 8e-77 pir||G71044 probable molybdopterin biosynthesis moeA protein - P... 282 6e-75 pir||C75170 molybdenum cofactor biosynthesis protein (moea-2) PA... 279 3e-74 gb|AAG18719.1| (AE004976) molybdenum cofactor biosynthesis prote... 266 4e-70 emb|CAC12151.1| (AL445066) molybdopterin biosynthesis protein (m... 261 1e-68 pir||A69049 molybdenum cofactor biosynthesis MoeA - Methanobacte... 255 6e-67 gi|11497778 molybdenum cofactor biosynthesis protein (moeA-3) [A... 241 1e-62 sp|Q58080|Y666_METJA PUTATIVE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN... 238 8e-62 dbj|BAA76925.1| (AB017192) molybdenum cofactor biosynthesis prot... 236 2e-61 gb|AAK42517.1| Molybdopterin biosynthesis protein (moeA-2) [Sulf... 235 6e-61 gb|AAG18720.1| (AE004977) molybdenum cofactor biosynthesis prote... 229 6e-59 emb|CAB59677.1| (AL132674) molybdopterin biosynthesis protein. [... 224 1e-57 pir||E70302 molybdenum cofactor biosynthesis protein A - Aquifex... 221 9e-57 pir||E82188 molybdopterin biosynthesis MoeA protein VC1527 [impo... 217 2e-55 dbj|BAB06740.1| (AP001517) molybdopterin biosynthesis [Bacillus ... 217 2e-55 sp|P12281|MOEA_ECOLI MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi... 215 5e-55 emb|CAC12152.1| (AL445066) molybdopterin biosynthesis protein (m... 210 2e-53 sp|Q39054|CNX1_ARATH MOLYBDOPTERIN BIOSYNTHESIS CNX1 PROTEIN (MO... 202 5e-51 sp|P45210|MOEA_HAEIN MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi... 200 2e-50 pir||C83266 molybdenum cofactor biosynthesis protein A2 PA3028 [... 200 2e-50 pir||E82439 molybdopterin biosynthesis MoeA protein VCA0617 [imp... 198 8e-50 dbj|BAA92623.1| (AB037806) KIAA1385 protein [Homo sapiens] 198 1e-49 gb|AAF81785.1|AF272663_1 (AF272663) gephyrin [Homo sapiens] 198 1e-49 gi|10880983 gephyrin; gephryin [Homo sapiens] >gi|10636475|emb|C... 198 1e-49 sp|Q03555|GEPH_RAT GEPHYRIN (PUTATIVE GLYCINE RECEPTOR-TUBULIN L... 198 1e-49 gi|11435181 gephyrin [Homo sapiens] 198 1e-49 pir||G70829 probable molybdenum cofactor biosynthesis protein - ... 196 4e-49 emb|CAA67416.1| (X98917) orf5 [Methanopyrus kandleri] 195 7e-49 pir||E69659 molybdopterin biosynthesis protein moeA - Bacillus s... 192 4e-48 gb|AAC83139.1| (AF109295) MoeA [Staphylococcus carnosus] 191 1e-47 sp|Q44243|MOEA_ANASP MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi... 190 3e-47 sp|O05577|MOEA_MYCTU MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi... 187 1e-46 pir||T45454 probable molybdenum cofactor biosynthesis protein [i... 187 2e-46 sp|Q56066|MOEA_SALTY MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi... 185 6e-46 gb|AAD49748.1|AF174130_1 (AF174130) gephyrin [Gallus gallus] 183 4e-45 pir||B75562 molybdopterin biosynthesis MoeA - Deinococcus radiod... 181 1e-44 gb|AAF73075.1|AF268595_1 (AF268595) molybdenum cofactor biosynth... 180 2e-44 pir||H83155 molybdenum cofactor biosynthetic protein A1 PA3914 [... 179 6e-44 pir||T46858 molybdenum cofactor biosynthesis protein A [imported... 176 3e-43 pir||G71966 molybdopterin biosynthesis protein - Helicobacter py... 167 2e-40 pir||D64541 molybdopterin biosynthesis protein - Helicobacter py... 167 2e-40 pir||T44851 molybdopterin co-factor synthesis protein moeA [impo... 163 4e-39 gb|AAK40978.1| Molybdopterin biosynthesis protein (moeA-1) [Sulf... 162 5e-39 emb|CAB57627.1| (Y18930) molybdopterin biosynthesis protein [Sul... 162 5e-39 emb|CAA04211.1| (AJ000662) MoeA protein [Wolinella succinogenes] 160 3e-38 sp|Q56207|MOEA_SYNP7 MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi... 159 7e-38 pir||A81359 probable molybdopterin biosynthesis protein Cj0857c ... 156 5e-37 emb|CAB57390.1| (AJ238348) MoeA protein [Rhodobacter capsulatus] 151 2e-35 pir||B81299 probable molybdopterin biosynthesis protein Cj1519 [... 148 8e-35 emb|CAB65851.1| (AL050231) alternatively spliced form [Drosophil... 142 6e-33 emb|CAB65852.1| (AL050231) EG:BACR37P7.3 [Drosophila melanogaste... 142 6e-33 sp|P39205|CIN_DROME MOLYBDENUM COFACTOR SYNTHESIS PROTEIN CINNAM... 142 8e-33 sp|Q55368|MOEA_SYNY3 MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi... 142 8e-33 pir||T20638 hypothetical protein T06H11.4 - Caenorhabditis elega... 131 1e-29 pir||H72739 probable molybdopterin biosynthesis moeA protein APE... 126 5e-28 pir||F72773 probable molybdopterin biosynthesis protein APE0177 ... 100 3e-20 pir||T36508 probable molybdenum cofactor biosynthesis protein - ... 98 2e-19 pir||T42407 gephyrin homolog - Caenorhabditis elegans >gi|281122... 93 5e-18 >pir||A75054 molybdenum cofactor biosynthesis protein (moea-1) PAB1436 - Pyrococcus abyssi (strain Orsay) >gi|5458839|emb|CAB50326.1| (AJ248287) molybdenum cofactor biosynthesis protein (moeA-1) [Pyrococcus abyssi] Length = 402 Score = 786 bits (2008), Expect = 0.0 Identities = 402/402 (100%), Positives = 402/402 (100%) Query: 1 MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60 MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA Sbjct: 1 MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60 Query: 61 VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120 VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV Sbjct: 61 VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120 Query: 121 ERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRK 180 ERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRK Sbjct: 121 ERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRK 180 Query: 181 PKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELI 240 PKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELI Sbjct: 181 PKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELI 240 Query: 241 EEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGL 300 EEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGL Sbjct: 241 EEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGL 300 Query: 301 PGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAV 360 PGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAV Sbjct: 301 PGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAV 360 Query: 361 PILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFEGW 402 PILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFEGW Sbjct: 361 PILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFEGW 402 >pir||B71173 probable molybdopterin biosynthesis moea protein - Pyrococcus horikoshii >gi|3256988|dbj|BAA29671.1| (AP000002) 402aa long hypothetical molybdopterin biosynthesis moea protein [Pyrococcus horikoshii] Length = 402 Score = 686 bits (1751), Expect = 0.0 Identities = 337/402 (83%), Positives = 370/402 (91%) Query: 1 MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60 MAFLKVVPLE+ALE+V SF + G EEV + + LGRI AEDIYSPID+PPFDRATVDGYA Sbjct: 1 MAFLKVVPLEKALEVVQSFKISPGIEEVPIEKGLGRIAAEDIYSPIDVPPFDRATVDGYA 60 Query: 61 VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120 VRAEDTFMASEA+P++LKV+G +HAGEEPK +L KGE YISTGAMLP NADAVIQFEDV Sbjct: 61 VRAEDTFMASEASPVRLKVIGSVHAGEEPKFKLGKGEAAYISTGAMLPGNADAVIQFEDV 120 Query: 121 ERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRK 180 ERV EI+IYKPAYPGLGVMKKG+DI KGRLLV+KGERLGFKQTALLSAVG+ +V+VFRK Sbjct: 121 ERVNGEILIYKPAYPGLGVMKKGIDIEKGRLLVKKGERLGFKQTALLSAVGINKVKVFRK 180 Query: 181 PKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELI 240 PKVA+ISTGNEIV PG+ELKPGQIYDINGRAL DA+NELGGEGIF+G+ARDD+ESLK LI Sbjct: 181 PKVAVISTGNEIVPPGNELKPGQIYDINGRALCDAINELGGEGIFMGVARDDKESLKALI 240 Query: 241 EEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGL 300 E+ V V D+VVISGGASGG +DLTASVIEELGEVKVHGIAIQPGKPTIIG I GKPVFGL Sbjct: 241 EKAVNVGDVVVISGGASGGTKDLTASVIEELGEVKVHGIAIQPGKPTIIGVIKGKPVFGL 300 Query: 301 PGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAV 360 PGYPTSCLTNFTLLVVPLLLRALGREGK+ K ARLKHK+FSVKGRRQFLPVKLEG +AV Sbjct: 301 PGYPTSCLTNFTLLVVPLLLRALGREGKIGKKVARLKHKVFSVKGRRQFLPVKLEGDLAV 360 Query: 361 PILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFEGW 402 PILKGSGAVTSFIDADGF+EIPETVES+DEGEEVEVTLF+GW Sbjct: 361 PILKGSGAVTSFIDADGFVEIPETVESLDEGEEVEVTLFKGW 402 >gi|11498536 molybdenum cofactor biosynthesis protein (moeA-1) [Archaeoglobus fulgidus] >gi|7429678|pir||C69366 molybdenum cofactor biosynthesis protein (moeA-1) homolog - Archaeoglobus fulgidus >gi|2649665|gb|AAB90307.1| (AE001039) molybdenum cofactor biosynthesis protein (moeA-1) [Archaeoglobus fulgidus] Length = 654 Score = 374 bits (950), Expect = e-102 Identities = 197/405 (48%), Positives = 273/405 (66%), Gaps = 8/405 (1%) Query: 3 FLKVVPLERALEIV-NSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAV 61 F VV ++ A ++ N F+ TE V L A GR++A+D+Y+ D+PPFDRAT+DGYAV Sbjct: 5 FRDVVTVDEARGLLFNHFSPRRKTEVVPLHLAAGRVLAKDVYALTDVPPFDRATMDGYAV 64 Query: 62 RAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVE 121 RAEDTF A E +P+ LKVVG + AG+ P+LE++ G+ V I+TGAM+PK A+AV+ E Sbjct: 65 RAEDTFEAEEDSPVTLKVVGTVEAGKRPELEVESGKAVEIATGAMMPKGANAVVMVEFTR 124 Query: 122 RVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKP 181 R DEI I+KP PG VM G D+ G L+ R+G L ++ +++A G+ V V+ +P Sbjct: 125 RREDEIDIFKPVSPGENVMYAGSDVMAGELIAREGTELTHREIGVMAACGISEVEVYCRP 184 Query: 182 KVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIE 241 KVAIISTGNE+V PG L G+IYD+N +++ AV E GGE I +GIARD+ E ++ +I Sbjct: 185 KVAIISTGNELVKPGERLGEGKIYDVNSYSIAAAVEENGGEAILMGIARDNEEEMRSIIA 244 Query: 242 EGVRVADIVVISGGASGGMRDLTASVIEELGE-VKVHGIAIQPGKPTIIGEINGKPVFGL 300 + +R ADIV+ SG S G D+ ++++ V VHGIAI+PGKP +I + KP+FGL Sbjct: 245 KALREADIVITSGSTSAGAGDVMYRILDDFHPGVIVHGIAIKPGKPAVIAVSDSKPIFGL 304 Query: 301 PGYPTSCLTNFTLLVVPLLLRALG-REGKVRKVKARLKHKIFSVKGRRQFLPVKL----E 355 PGYPTS +T F ++V P++ G RE KV+ARL K+FS +GRR++LPV + E Sbjct: 305 PGYPTSAMTVFEVIVAPIIRELAGRRESSGAKVRARLAIKVFSAEGRREYLPVNVVEGAE 364 Query: 356 GGVAVPILKG-SGAVTSFIDADGFIEIPETVESVDEGEEVEVTLF 399 G A P+ SGAVT+F DGF+EIPE V ++EG+EVEV LF Sbjct: 365 GYSAYPVSGSYSGAVTAFAFTDGFVEIPENVVMLEEGDEVEVKLF 409 >pir||G69000 molybdenum cofactor biosynthesis protein MoeA - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622104|gb|AAB85499.1| (AE000873) molybdenum cofactor biosynthesis protein MoeA [Methanobacterium thermoautotrophicum] Length = 409 Score = 342 bits (867), Expect = 5e-93 Identities = 181/402 (45%), Positives = 250/402 (62%), Gaps = 4/402 (0%) Query: 3 FLKVVPLERALEIVNSFTLPL---GTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGY 59 FL+++ L+ A I L GTE V + +A GR++A+DI SP+D+PPFDRA+ DGY Sbjct: 6 FLEIIDLDDARRITGELFSELYSQGTESVDILDADGRVLADDIESPVDLPPFDRASRDGY 65 Query: 60 AVRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFED 119 AVRA DTF A E NP L+ + + AG P LE+ +G ISTGA +P+ ADAV+ E Sbjct: 66 AVRAADTFGADEENPATLRCIETVEAGSVPSLEVAEGLCTRISTGAPVPEGADAVVMVEY 125 Query: 120 VERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFR 179 D + I +PAYP + +G DI G +L+R G L + A LSA G+ RV V Sbjct: 126 TWEEVDRVYIQRPAYPSQHIAARGSDIRAGNVLLRTGTVLSPDKIAALSAAGITRVNVIS 185 Query: 180 KPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKEL 239 KP V +ISTGNE++ P +L+PG+I+D N LS A+ E G GI RDD L++ Sbjct: 186 KPSVCVISTGNELIEPSGQLEPGKIFDSNSAGLSSALKEAGCSVKHGGIVRDDYGELRDA 245 Query: 240 IEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFG 299 I G+ AD+V+ SGG S G D+ + V++ELG V +HGI+I+PGKPTI+G ++ K V G Sbjct: 246 ILRGLEEADMVITSGGTSAGAGDILSEVLDELGRVVIHGISIKPGKPTIVGVVDDKIVVG 305 Query: 300 LPGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKA-RLKHKIFSVKGRRQFLPVKLEGGV 358 LPG+P S L F L+ P + + GR+ VK +L ++ S +GR + V ++G Sbjct: 306 LPGFPVSALIVFMSLIEPFIRKLSGRKASSGHVKTLKLAERLHSSRGRVHYALVMVDGDY 365 Query: 359 AVPILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFE 400 A PI K SGAV + ADG+IE+P+ VE ++EGEEVEV LFE Sbjct: 366 ARPIFKDSGAVAALAGADGYIEVPKNVEIINEGEEVEVVLFE 407 >sp|Q58296|Y886_METJA PUTATIVE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN MJ0886 >gi|2129131|pir||F64410 molybdenum cofactor biosynthesis protein moeA homolog - Methanococcus jannaschii >gi|1591564|gb|AAB98890.1| (U67532) molybdenum cofactor biosynthesis protein (moeA) [Methanococcus jannaschii] Length = 620 Score = 339 bits (860), Expect = 4e-92 Identities = 192/404 (47%), Positives = 263/404 (64%), Gaps = 19/404 (4%) Query: 3 FLKVVPLERALEIVNSFTLPLGTE--EVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60 +L + +E A I+N L E EV L A+GR++AED++S IDIPP+DRA +DGYA Sbjct: 4 YLTLHSIEEAKSIINESLKKLKNEVEEVDLFNAIGRVLAEDVFSNIDIPPYDRAKMDGYA 63 Query: 61 VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120 V+AEDT+ A E NP++LKV+G + AGE LE+ GE V I+TGA++PK A+AV+ E Sbjct: 64 VKAEDTYEADEDNPVELKVIGSLKAGEIKDLEINNGECVEIATGAIIPKGANAVVMVEYT 123 Query: 121 ERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRK 180 ER D + IY+ P + G DI G L++RK +L + +L+A+G +V+V++K Sbjct: 124 ERDNDRVKIYRAVPPMENIQFTGSDIMAGELVLRKNTKLTPRDIGVLAAIGKSKVKVYKK 183 Query: 181 PKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELI 240 K IISTGNEI+ P +L+ G+IYDIN L + LG + F GIA+DD+E LKE I Sbjct: 184 LKFGIISTGNEIISPNEQLEFGKIYDINSYTLVSYIKTLGYDFEFFGIAKDDKEELKEKI 243 Query: 241 EEGVRVADIVVISGGASGGMRDLTASVIEELG-EVKVHGIAIQPGKPTIIGEINGKPVFG 299 ++ ++ DI+++SGG S G+ DLT + I+ELG ++ VHGI I+PGKPTIIG+I+ K + G Sbjct: 244 KKALK-CDIILLSGGTSAGVGDLTETAIKELGGKILVHGIKIKPGKPTIIGKIDNKLIVG 302 Query: 300 LPGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKL----E 355 LPGYPTSCLT F +L G E V VKA+ + S KGR ++LPV L Sbjct: 303 LPGYPTSCLTIFDVL--------FGDEKNV--VKAKFPVRYISAKGRVEYLPVILVKHKN 352 Query: 356 GGVAVPILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLF 399 G A PI KGSGA+TS +ADG+I I E E + E E+VEV LF Sbjct: 353 GFSAYPITKGSGAITSLSEADGYIIIDENKE-ILENEDVEVHLF 395 >gi|11498535 molybdenum cofactor biosynthesis protein (moeA-2) [Archaeoglobus fulgidus] >gi|7429691|pir||B69366 molybdenum cofactor biosynthesis protein (moeA-2) homolog - Archaeoglobus fulgidus >gi|2649666|gb|AAB90308.1| (AE001039) molybdenum cofactor biosynthesis protein (moeA-2) [Archaeoglobus fulgidus] Length = 414 Score = 288 bits (729), Expect = 8e-77 Identities = 158/380 (41%), Positives = 231/380 (60%), Gaps = 5/380 (1%) Query: 23 LGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGE 82 L TE+V + GR++AEDI + D+P F+RA +DGYAV+AEDTF AS +NPI L++ G Sbjct: 27 LETEDVSVYNLQGRVLAEDIVAGFDVPKFNRAAMDGYAVKAEDTFGASVSNPIMLQLAGS 86 Query: 83 IHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAYPGLGVMKK 142 + GE PK+ ++ G V I TGAM+P+ +AV+ E G+ + + K P V + Sbjct: 87 VEIGEVPKVVVESGMAVRIMTGAMMPEGTNAVVMLEHTRLNGNFVEVLKSVTPMKNVSRV 146 Query: 143 GVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELKPG 202 G DI+ G ++ RKGE L + +++++G+E VRV+RKP+VA+I+TGNE+ G L+ Sbjct: 147 GEDIAAGEVVFRKGEILQPQDAGVIASLGIESVRVYRKPRVAVITTGNELAEVGEPLEGA 206 Query: 203 QIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISGGASGGMRD 262 +IY+ N + +A+ E G E I LGIARDD E L+ +++ + D VI+GG S G +D Sbjct: 207 KIYNSNNPMICNALLEFGFEAISLGIARDDEEELRNKLQKALEF-DAAVITGGTSVGAKD 265 Query: 263 LTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFTLLVVPLLLRA 322 L V+ E GE+ HG++++PG PT + GKPVF LPG P + L F +P L R Sbjct: 266 LVPDVVGEFGEIVFHGVSMKPGMPTGAAVVEGKPVFMLPGSPAAALLGFYTFAIPALYRM 325 Query: 323 LGREGKVRK---VKARLKHKIFSVKGRRQFLPVKLEGGVAVPI-LKGSGAVTSFIDADGF 378 + RK K L+ +I S G R + V E G PI + GSG ++SF+ A+ Sbjct: 326 MNVRIIARKWSRQKGVLQGRIPSEIGVRSNVRVLWEDGKVYPIRISGSGILSSFVRANAL 385 Query: 379 IEIPETVESVDEGEEVEVTL 398 + +PE E +EGEEVEVTL Sbjct: 386 LVVPEDKEGYEEGEEVEVTL 405 >pir||G71044 probable molybdopterin biosynthesis moeA protein - Pyrococcus horikoshii >gi|3258076|dbj|BAA30759.1| (AP000006) 396aa long hypothetical molybdopterin biosynthesis moeA protein [Pyrococcus horikoshii] Length = 396 Score = 282 bits (713), Expect = 6e-75 Identities = 166/403 (41%), Positives = 237/403 (58%), Gaps = 12/403 (2%) Query: 1 MAFLKVVPLERALEIV-NSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGY 59 M F K+VP AL+++ + TE+V L EA+GR++AEDI + DIPPFDRA VDGY Sbjct: 2 MEFKKLVPYREALKLLLDDINEIEDTEKVPLREAVGRVLAEDIVTEFDIPPFDRAAVDGY 61 Query: 60 AVRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFED 119 A+RAEDTF A E NPI+L V+ E+ AG K E+ G+ + + TG +PK A+AVI E Sbjct: 62 AIRAEDTFQAREYNPIELTVIEEVPAGNVAKEEVTTGKAIKVLTGTRIPKGANAVIMQEM 121 Query: 120 VERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFR 179 V+R GD+I + +P PG + G D+ KG +++RKG L + A+L A+G+++V V Sbjct: 122 VKREGDKIYVLRPVAPGQNIAFTGEDVKKGEVVLRKGTILRPQDVAMLKALGIKKVPVKV 181 Query: 180 KPKVAIISTGNEIVLPGSE--LKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLK 237 KPKV II TG+E++ SE K G+I + N L V + GE I G+ DD +K Sbjct: 182 KPKVGIIITGSELIEEPSEEGFKEGKIVETNSIMLQGLVEKFFGEPILYGVLPDDESIIK 241 Query: 238 ELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPV 297 E +E+ DIV+I+GG++ G +D + L HG I+PG+P GE V Sbjct: 242 ETLEKAKNECDIVLITGGSAFGDKDYAHKFVNLL----FHGTTIKPGRPFGYGE----KV 293 Query: 298 FGLPGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGG 357 F + GYP S F L V L + +G + KVKA L+ I S GR +F+ + E G Sbjct: 294 FIMSGYPVSVFAQFNLFVKHALAKMVGAQNYEVKVKAILQDDIPSQLGRYEFIKIYYENG 353 Query: 358 VAVPI-LKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLF 399 +A I KGSG ++S + ++ ++EIPE E GEEV +TL+ Sbjct: 354 IARVIKKKGSGILSSLLASNAYLEIPEDSEGYRRGEEVWITLY 396 >pir||C75170 molybdenum cofactor biosynthesis protein (moea-2) PAB2014 - Pyrococcus abyssi (strain Orsay) >gi|5457952|emb|CAB49442.1| (AJ248284) molybdenum cofactor biosynthesis protein (moeA-2) [Pyrococcus abyssi] Length = 395 Score = 279 bits (707), Expect = 3e-74 Identities = 159/403 (39%), Positives = 241/403 (59%), Gaps = 12/403 (2%) Query: 1 MAFLKVVPLERALEIV-NSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGY 59 M F K++P AL ++ N T E V L EAL R++A+DI S D+PPFDR+ VDGY Sbjct: 1 MEFKKLMPYREALTLLLNDVTEIQDVEHVPLDEALNRVLAQDIISEFDVPPFDRSAVDGY 60 Query: 60 AVRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFED 119 AVRAEDTF A E +PI+LKV+ E+ AGE PK+++ G + + TGA +P+ A+AVI E Sbjct: 61 AVRAEDTFQAREYSPIELKVIEEVPAGESPKMKVTSGTAIKVLTGAKIPEGANAVIMQEM 120 Query: 120 VERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFR 179 V+R G++I + +P PG V KG D+ KG +++RKG L + A+L A+G++ V V R Sbjct: 121 VKREGEKIYVLRPVAPGQNVAFKGEDVKKGEVILRKGTILRPQDLAMLKALGIKSVPVKR 180 Query: 180 KPKVAIISTGNEIVLPGSE--LKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLK 237 KP+V II TG+E+V SE + G+I + N L V++ GE I G+ D+ + ++ Sbjct: 181 KPRVGIIITGSELVEEPSEDAFEEGKIVETNSIMLKSLVHKFFGEPILYGVIPDEEDKIR 240 Query: 238 ELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPV 297 E I++ R D+V+++GG++ G +D ++ L HG I+PG+P GE V Sbjct: 241 EAIKKAKRECDLVLVTGGSAFGDKDYAHRFVKLL----FHGTTIKPGRPIGYGE----RV 292 Query: 298 FGLPGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGG 357 F + GYP + F L V L + +G K++A L+ + S GR +F+ V G Sbjct: 293 FIMSGYPVAVFAQFHLFVKHALAKMVGARDYEVKLRAILEDDVPSQLGRHEFVKVLYRDG 352 Query: 358 VAVPI-LKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLF 399 A I KGSG ++S ++++ ++E+PE E GEEV +TL+ Sbjct: 353 KAKVIKKKGSGIISSLVESNAYLEVPEDSEGYRRGEEVWITLY 395 >gb|AAG18719.1| (AE004976) molybdenum cofactor biosynthesis protein; MoeA2 [Halobacterium sp. NRC-1] Length = 571 Score = 266 bits (672), Expect = 4e-70 Identities = 150/354 (42%), Positives = 207/354 (58%), Gaps = 10/354 (2%) Query: 56 VDGYAVRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVI 115 +DGYAVRA DTF ASEA+P +L V G +HAGEEP +E+ G V +STGA++P ADAV+ Sbjct: 1 MDGYAVRAADTFGASEADPARLSVAGTVHAGEEPAVEVTAGRAVVVSTGAVMPPGADAVV 60 Query: 116 QFEDVERV--GDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVE 173 + E GD + + PG VM G DI+ G + G +L ++ +LSA+GV Sbjct: 61 KVEATTEADGGDAVDVRTSVAPGTAVMLAGADIAAGSRAIGPGTKLTAREIGVLSALGVG 120 Query: 174 RVRVFRKPKVAIISTGNEIVLPGSELKP--GQIYDINGRALSDAVNELGGEGIFLGIARD 231 VRV P V IISTG+E+V PG L GQI+D+N ++ AV GGE + A D Sbjct: 121 SVRVRGAPTVGIISTGDELVRPGDPLDSAAGQIHDVNSHTIAAAVEAAGGEPVVYPHAGD 180 Query: 232 DRESLKELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGE 291 D ++ L+ E D+V+ SG S D+ V EE G++ +HG+A++PGKP ++GE Sbjct: 181 DYAEMERLLVESAADCDLVLSSGSTSASAVDVIYRVAEERGDLLLHGVAVKPGKPMLVGE 240 Query: 292 INGKPVFGLPGYPTSCLTNFTLLVVPLLLRALGR-EGKVRKVKARLKHKIFSVKGRRQFL 350 I G GLPGYP S LT F + V P++ A GR + + V + + S +GRR+ L Sbjct: 241 IEGTAYVGLPGYPVSALTIFRVFVAPVVREAAGRGQPEPTVVTGEMARQERSAEGRRRLL 300 Query: 351 PVKL-EGG----VAVPILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLF 399 PV L E G + P+ KGSGA TS +DADG + +P V G+ V+V LF Sbjct: 301 PVGLVEDGAGDRLVYPVDKGSGATTSLVDADGTVTVPADTAYVAAGDSVDVALF 354 >emb|CAC12151.1| (AL445066) molybdopterin biosynthesis protein (moeA-1) related protein [Thermoplasma acidophilum] Length = 626 Score = 261 bits (660), Expect = 1e-68 Identities = 145/371 (39%), Positives = 217/371 (58%), Gaps = 4/371 (1%) Query: 27 EVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIHAG 86 EV + EA+G AEDI+S D+PPFDR+ VDG+AV D A E P+ L++ G I G Sbjct: 29 EVPIEEAVGLTAAEDIFSQYDVPPFDRSEVDGFAVDHADVDGAQEDAPVTLRIAGSISPG 88 Query: 87 EEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAYPGLGVMKKGVDI 146 E + +++G+ VYI+TG+++PK +DAV+ ED + GD + IY+ YPG V G DI Sbjct: 89 ETGNVTVERGKAVYIATGSVMPKGSDAVVMVEDTRQHGDYVDIYRSVYPGENVAFAGTDI 148 Query: 147 SKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELKPGQIYD 206 S G ++ + G L ++ A L+A GV RVRVF + ++ I STGNEIV PG+ LK GQI+D Sbjct: 149 SLGDIIAKAGTVLTPEKLATLAASGVARVRVFDRIRIGIFSTGNEIVRPGTNLKLGQIFD 208 Query: 207 INGRALSDAVNELGG-EGIFLGIARDDRESLKELIEEGVRVADIVVISGGASGGMRDLTA 265 +NG ++ GG +FLG D + + ++I + + DI++ SG S G D+ Sbjct: 209 VNGYYFQTKLSSSGGVHAVFLGSVPDREDDMVKIIRDNLDSFDILMASGSTSAGFLDMLY 268 Query: 266 SVIEEL-GEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFTLLVVPLLLRAL- 323 VIE++ G + HGI ++PGKPT G I K G+PG+P S +V+P + +A+ Sbjct: 269 RVIEKVGGSILFHGINMRPGKPTFFGRIGEKLFIGMPGFPLSSAVILNYIVIPSIRKAIS 328 Query: 324 GREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAVPILKGSGAVTSFIDADGFIEIPE 383 G + R VK +K ++ + + G A PI+ SG+++ ADGFI IP Sbjct: 329 GDFERPRVVKVPVKIAPDHMQ-ETVYPAIITRNGYAFPIMGNSGSISRIRFADGFIAIPG 387 Query: 384 TVESVDEGEEV 394 ++ VD G+ V Sbjct: 388 DLKYVDPGDNV 398 >pir||A69049 molybdenum cofactor biosynthesis MoeA - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622477|gb|AAB85846.1| (AE000899) molybdenum cofactor biosynthesis MoeA [Methanobacterium thermoautotrophicum] Length = 404 Score = 255 bits (645), Expect = 6e-67 Identities = 146/404 (36%), Positives = 228/404 (56%), Gaps = 8/404 (1%) Query: 1 MAFLKVVPLERALEIVNS---FTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVD 57 M +++P+ A I++ FT P E V L EA R++A+DI S D PPFDR+ +D Sbjct: 1 MFLSELLPVRDAFRILDENQRFTEP---ETVDLLEAYHRVLADDIVSRFDSPPFDRSAMD 57 Query: 58 GYAVRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQF 117 GYAVRAEDTF +S NP L+V I AGE +++ GE V I+TGA +P ADAV+ Sbjct: 58 GYAVRAEDTFGSSPGNPSTLRVTDSIGAGEVSGVDVGHGEAVRIATGAPIPAGADAVVME 117 Query: 118 EDVERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRV 177 E + G +I + +P P V G D+ +G ++R+G + ++ A+ ++ G +VRV Sbjct: 118 EYTLQDGPDIRVLRPVAPSENVAPAGEDVRRGVTVLREGTLMRPQEIAMAASAGYSKVRV 177 Query: 178 FRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLK 237 FR+P V +I TGNE+V P +L+PG++ + N L+ V GG + + DD +++ Sbjct: 178 FRRPSVKVIVTGNELVDPSDDLEPGKVPNSNLYTLNALVESAGGSADPVHLP-DDIDTVG 236 Query: 238 ELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPV 297 E IE D+++ +GG + D+ ++ LGEV HG+A++PGKP G ++ PV Sbjct: 237 EEIESSASEYDVIITTGGTAISRGDVVVDAVDGLGEVLFHGVALRPGKPVAFGMVSETPV 296 Query: 298 FGLPGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGG 357 F L GYP + + F + LLR + + R VK R + K+ S GR +L + Sbjct: 297 FMLSGYPVAAMVQFDVFARYYLLRMQHLDYRHRAVKRRCRAKVASGPGRTDYLRAWADDE 356 Query: 358 VAVPI-LKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFE 400 P+ +GSG + S + ++ +I I E +E + GEE +V LF+ Sbjct: 357 EVEPVQSRGSGIIRSMVGSNAYIVIDENLEGISAGEECDVLLFD 400 >gi|11497778 molybdenum cofactor biosynthesis protein (moeA-3) [Archaeoglobus fulgidus] >gi|7445252|pir||A69270 molybdenum cofactor biosynthesis protein (moeA-3) homolog - Archaeoglobus fulgidus >gi|2650482|gb|AAB91068.1| (AE001095) molybdenum cofactor biosynthesis protein (moeA-3) [Archaeoglobus fulgidus] Length = 400 Score = 241 bits (609), Expect = 1e-62 Identities = 151/404 (37%), Positives = 224/404 (55%), Gaps = 39/404 (9%) Query: 14 EIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEAN 73 E+ F +EEV++ +AL R +AED+++ D+PPFD AT+DGYA++ ED Sbjct: 19 ELRQRFYFKRESEEVRVEDALDRELAEDVFAAKDMPPFDIATMDGYALKLEDGVR----- 73 Query: 74 PIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPA 133 + ++VGE++AGE + +GE VYI+TGA +P NAD V++ E E G ++ I + Sbjct: 74 --EYRIVGEVYAGEVEDRFVNRGECVYITTGAKMPVNADTVVKVEIAEVDGSKMRIREKV 131 Query: 134 YPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIV 193 G V+KKG ++ KG L++ R+G ++ A L + GVERVRVFR+ + A+ S G+EI Sbjct: 132 NRGKYVLKKGSEVKKGDLILPAKTRIGPQEIAALISAGVERVRVFRRLRAAVFSNGDEI- 190 Query: 194 LPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVIS 253 K G I D N +S + +LG E FLG+A DD E ++E++E+GVR D V+ S Sbjct: 191 ------KKGIIADSNSAMISAFLRKLGCEVHFLGVAGDDAEEVREMVEKGVRDYDAVLTS 244 Query: 254 GGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFTL 313 GG S G +D ++E+GEV ++ + +PGKP ++ +N KPVF LPG P C T Sbjct: 245 GGVSVGEKDYVVKALKEMGEVLIYKVRQRPGKPMVVAVVNEKPVFALPGKPAGCFT---- 300 Query: 314 LVVPLLLRALGREGKVRKVKARLKHKI-FSVKGRRQFLPVKLEGGVAVP---------IL 363 + L R + KV+AR+ + KG FL VKL G A+P I+ Sbjct: 301 -AMLSLRRFFAGDKPFPKVRARIAGDVKLPTKGFSYFLFVKLRDGYAIPAGFRHSHVSII 359 Query: 364 KGSGAVTSFIDA-------DGFIEIPETVESVDEGEEVEVTLFE 400 S + A DGF+ T + GEEVEV L++ Sbjct: 360 PYEKYEVSLVSAMARSAVSDGFV---VTDRDLRAGEEVEVCLYD 400 >sp|Q58080|Y666_METJA PUTATIVE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN MJ0666 >gi|2129130|pir||B64383 molybdenum cofactor biosynthesis protein moeA homolog - Methanococcus jannaschii >gi|1591380|gb|AAB98661.1| (U67514) molybdenum cofactor biosynthesis protein (moeA) [Methanococcus jannaschii] Length = 398 Score = 238 bits (601), Expect = 8e-62 Identities = 148/384 (38%), Positives = 217/384 (55%), Gaps = 26/384 (6%) Query: 26 EEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIHA 85 +EV + EAL RI AEDI +PID+P F++A +DGYAV AEDTF ASE NPI L + Sbjct: 32 KEVDIVEALNRISAEDIKAPIDLPYFNKAAMDGYAVIAEDTFGASETNPIILNLAD---- 87 Query: 86 GEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAYPGLGVMKKGVD 145 G+E + GE I TG LPKNA+AV+ E V D + +YK +P V + G D Sbjct: 88 GDE----ITYGEAKKIFTGDKLPKNANAVVMKEFCNEVDDFVEVYKTVHPNENVSRIGED 143 Query: 146 ISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELKP---- 201 + KG ++++KGE + +L+++G+++++V+ IISTG+E++ E++ Sbjct: 144 VKKGDVVLKKGEIINPYHLNMLASLGIKKIKVYDL-SFGIISTGDELINL-DEIRDIEED 201 Query: 202 -----GQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISGGA 256 G+I + N L V LG I +DD+E LK+ I+ + D ++I+GG Sbjct: 202 ISKLDGKIINSNSYMLYGLVKNLGFNAKIYDIVKDDKEKLKKAIKTALSENDALLITGGT 261 Query: 257 SGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFTLLVV 316 S RD+T + ELG+V VHG+ I+PGKP G IN KPVF L GYP + F L + Sbjct: 262 SVSERDITVETVRELGDVIVHGVNIRPGKPFGFGIINDKPVFMLSGYPVASAVQFELFIQ 321 Query: 317 PLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAVPILKGSGAVTSFIDAD 376 + +KV LK + S GR F+ VK++ V + GSG ++S I +D Sbjct: 322 RFFIER-------KKVTLPLKRNMASELGRVDFVRVKVDIEVEPIRITGSGVISSLIKSD 374 Query: 377 GFIEIPETVESVDEGEEVEVTLFE 400 G+I IPE VE ++GE V+V L + Sbjct: 375 GYILIPENVEGYEKGELVDVYLLK 398 >dbj|BAA76925.1| (AB017192) molybdenum cofactor biosynthesis protein [Clostridium perfringens] Length = 406 Score = 236 bits (597), Expect = 2e-61 Identities = 146/401 (36%), Positives = 226/401 (55%), Gaps = 9/401 (2%) Query: 5 KVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAE 64 K + LE ALEI+N T L +E V + ++L R++ D+ S I+ PPF+++ DGYA ++E Sbjct: 3 KFIALEEALEILNKNTKALKSEVVSIKDSLKRVLYGDVKSKINNPPFNKSVFDGYAFKSE 62 Query: 65 DTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVG 124 D+ S+ NPI+LK+V EI AG+ ++E+K GE + I TGA +P AD V++ E+ ER G Sbjct: 63 DSKGTSKENPIELKIVDEIFAGDFSEIEIKHGEAIRIMTGAPIPVGADCVLKQEETERHG 122 Query: 125 DEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVA 184 D + I+K + G DI G L++KG+RL + ++++ G+ V V++KPKV+ Sbjct: 123 DLVKIFKEMKANENISFMGEDIKIGETLIKKGKRLDYADLGIMASSGISEVLVYKKPKVS 182 Query: 185 IISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGV 244 IISTG+E+ S LKPG+IYD N +LS + ELG + + D+ + E IE+ Sbjct: 183 IISTGDEVCDINSTLKPGKIYDSNLYSLSARIEELGYNVLSMEHVGDNILKIGEAIEKAF 242 Query: 245 RVADIVVISGGASGGMRDLTASVIEELG-EVKVHGIAIQPGKPTIIGEINGKPVFGLPGY 303 +DIV +GGAS G +DL V +G E I I+PG + + K + L G Sbjct: 243 EKSDIVFTTGGASVGEKDLMQKVSGSIGFERLFWKIKIKPGSAVVCSKRQEKILISLSGN 302 Query: 304 PTSCLTNFTLLVVPLLLRALGREG--KVRKVKARLKHKIFSVKGRRQFLPVKL---EGGV 358 P + LT F LL P+L + G E +++ K L +R+FL + E G Sbjct: 303 PNAALTTFELLGKPVLKKLEGEEENINIKREKGVLMDSFNKKSPQRRFLRGNIIYDEKGA 362 Query: 359 AV---PILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEV 396 V I G+G ++S ++A+ IEI + E ++ GE V + Sbjct: 363 KVYITQIKSGNGILSSLLNANCLIEIEKGNEGLNRGEVVNI 403 >gb|AAK42517.1| Molybdopterin biosynthesis protein (moeA-2) [Sulfolobus solfataricus] Length = 550 Score = 235 bits (594), Expect = 6e-61 Identities = 145/401 (36%), Positives = 234/401 (58%), Gaps = 21/401 (5%) Query: 9 LERALEI-VNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTF 67 +E A+ + ++S T EV++ ++ G + AED+ SPID PPF R+ VDGYA++ Sbjct: 17 IEEAIRVYLSSLNFIPKTVEVEVKDSFGYVSAEDLNSPIDYPPFSRSNVDGYALK----- 71 Query: 68 MASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEI 127 S P +LKV+ I GE ++ + + V + TGA++P ADAVI+ EDV+ + + Sbjct: 72 --SSCTPGELKVIDRIEIGEFKEVHINECVAVEVDTGAIIPMGADAVIKVEDVKIISGNL 129 Query: 128 I-IYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAII 186 I + K G + G DI K +++RKGE + ++ LL+++G+ +V+V+ K KV +I Sbjct: 130 IKVDKKMTFGQNIGWIGSDIPKNSIILRKGEVISHEKIGLLASLGISKVKVYEKLKVYLI 189 Query: 187 STGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRV 246 +TG+E+V PG+ L PG+IY+ N L + + + + L + RDD ES+K I+ + + Sbjct: 190 ATGDELVEPGNSLSPGKIYESNLHYLYSKLKQ-NYQIVGLSLLRDDIESIKNEIKRAISL 248 Query: 247 ADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTS 306 AD+++++GG S G +D I+ELG + VHGI I+PGKPTI+G ++ KPV GLPG S Sbjct: 249 ADVLILTGGTSAGEKDFVHRAIKELGSIIVHGIKIKPGKPTILGVVDNKPVIGLPGNIVS 308 Query: 307 CLTNFTLLVVPLLLRALGREGK----VRKVKARLKHKIFSVKGRRQFLPVKLEGGV---- 358 + F V+ +LR L K + K+KA+L + K R +PV L V Sbjct: 309 SVVVFD-TVISEILRNLYPSRKEIVELGKIKAKLALGTKADKYRNTLIPVYLFKSVDSSY 367 Query: 359 -AVPILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTL 398 A+P+ S + +F +G+I + E ++EG+EVEV + Sbjct: 368 YALPVKFESYMIGTFSLTEGYIMLNPN-EEIEEGKEVEVNV 407 >gb|AAG18720.1| (AE004977) molybdenum cofactor biosynthesis protein; MoeA1 [Halobacterium sp. NRC-1] Length = 407 Score = 229 bits (577), Expect = 6e-59 Identities = 148/400 (37%), Positives = 209/400 (52%), Gaps = 25/400 (6%) Query: 10 ERALEIVNSFTLPLG-TEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFM 68 ER L V+ PL T V L +A GR++A D+ +P +P ++RA +DG+AVRA DTF Sbjct: 21 ERLLSAVD----PLARTARVALGDADGRVLAADVEAPRAVPHYERAAMDGFAVRAADTFG 76 Query: 69 ASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEII 128 A + +P+ L V G G GE V + TG+ LP ADAV+ ED ER GD + Sbjct: 77 AGDRSPVVLDV-GTGSVGP--------GEAVRVHTGSELPAGADAVVMIEDAERRGDRVD 127 Query: 129 IYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIIST 188 ++ A G V G D+S G+ L G RL LL + GV+ V V+ +P V ++ T Sbjct: 128 VFAAAAGGANVAPIGEDVSDGQHLYDAGHRLRPSDLGLLKSAGVDAVAVYERPTVGVLPT 187 Query: 189 GNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVAD 248 G E+V ++ PG++ + NG ++ V+ GG G+ DD +L+ I E V D Sbjct: 188 GEELV--AADPGPGEVVETNGGTVAQYVSRWGGVPTRRGVVTDDEAALRTAIREAVDSHD 245 Query: 249 IVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCL 308 +VV +GG+S G RD VI +LG V VHG+A+QPG P + ++ PV LPGYP + + Sbjct: 246 VVVTTGGSSVGARDHVPEVIADLGTVLVHGVALQPGHPVALCVVDDTPVVALPGYPVAAI 305 Query: 309 TNFTLLVVPLLLRALGREGKVR--KVKARLKHKIFSVKGRRQFLPVKLEGG------VAV 360 N + P LL+A+G A L KI S G R F+ V G V Sbjct: 306 VNAVQFLRP-LLKAVGHAPATAHPTTDAVLARKIASEPGTRSFVRVTRHGDEDGRPTVTP 364 Query: 361 PILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFE 400 GSG ++S ADG++ +PE E D G V V +E Sbjct: 365 TRAGGSGVLSSVALADGWVVVPEDCEGYDAGTTVAVEQWE 404 >emb|CAB59677.1| (AL132674) molybdopterin biosynthesis protein. [Streptomyces coelicolor A3(2)] Length = 424 Score = 224 bits (565), Expect = 1e-57 Identities = 149/418 (35%), Positives = 213/418 (50%), Gaps = 32/418 (7%) Query: 13 LEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEA 72 L+ V + PL E+ L +A G ++ +DI P+ +PPFD +++DGYAVR D ASE Sbjct: 5 LDDVLATVRPLDPIELNLLDAQGCVLVDDITVPLSLPPFDNSSMDGYAVRVTDVAGASEE 64 Query: 73 NPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDE------ 126 P L+VVG++ AG+ + + G+ I TGA LP A+AV+ E + E Sbjct: 65 FPAVLEVVGDVAAGQTDPIAVGPGQAARIMTGAPLPPGAEAVVPVEWTDGGSGEGPVAGM 124 Query: 127 -------------IIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVE 173 + +Y+PA V KG D+ G + G LG Q LL+A+G Sbjct: 125 RARSLAPEGAEGHVQVYRPAEERAHVRAKGSDVRSGDRALAAGTVLGPPQIGLLAAIGRG 184 Query: 174 RVRVFRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDR 233 VRV +P+V ++STG+E+V P +L PGQIYD N AL+ A + G +G DD Sbjct: 185 TVRVRPRPRVVVLSTGSELVQPDEQLAPGQIYDSNSFALTAAARDAGAIAYRVGAVADDA 244 Query: 234 ESLKELIEEGVRVADIVVISGGASGGMRDLTASVIEELGE-------VKVHGIAIQPGKP 286 E+L+ IE+ + AD++V +GG S G D+ + +G+ V +A+QPGKP Sbjct: 245 ETLRATIEDQLVRADLMVTTGGVSVGAYDVVKEALAHVGDEDEPGGGVDFRKLAMQPGKP 304 Query: 287 TIIGEI--NGKPVFGLPGYPTSCLTNFTLLVVPLLLRALGREGKVR-KVKARL--KHKIF 341 G + + P+ LPG P S +F L V P + +G R V A L + Sbjct: 305 QGFGSVGPDHTPLLALPGNPVSSYVSFELFVRPAIRTLMGLPDVHRPTVTASLAADKALT 364 Query: 342 SVKGRRQFLPVKLEGGVAVPI-LKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTL 398 S KGRRQFL GG P+ GS V + A+ I +PE ESV+ G EVEV L Sbjct: 365 SPKGRRQFLRGSHAGGSVTPVGGSGSHLVAALAQANALIVVPEDTESVEPGTEVEVVL 422 >pir||E70302 molybdenum cofactor biosynthesis protein A - Aquifex aeolicus >gi|2982782|gb|AAC06407.1| (AE000670) molybdenum cofactor biosynthesis protein A [Aquifex aeolicus] Length = 402 Score = 221 bits (558), Expect = 9e-57 Identities = 152/404 (37%), Positives = 223/404 (54%), Gaps = 15/404 (3%) Query: 6 VVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAED 65 + PLE AL+IV PL +E V + EALGR++AED+ S D P FD + +DGYAVR ED Sbjct: 4 LTPLEEALKIVLENVKPLESERVFIHEALGRVLAEDVVSDTDKPLFDNSAMDGYAVRWED 63 Query: 66 TFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGD 125 + P KLKV+GE AG L+++KG V I TGA +P+ AD V+ E E Sbjct: 64 I----KEVPAKLKVIGEYAAGTGENLKVEKGTAVKIFTGAPIPEGADTVVPVEYTETQDG 119 Query: 126 EIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAI 185 +I+ K G V ++G D+ KG +++ KG+ + + +L++V V V+RKP V I Sbjct: 120 YVIVKKSFKQGANVRRRGEDVKKGEVVIPKGKEIRPYEMGMLASVNRAVVSVYRKPHVGI 179 Query: 186 ISTGNEIV-LPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGV 244 +STG+EI+ + + KP QI N + V + GG LGIA D+ + LKE++ + Sbjct: 180 LSTGDEILDVCEEQTKPSQIRTSNNYTVYGQVLQAGGIPHNLGIAPDEPQKLKEIM-RSI 238 Query: 245 RVADIVVISGGASGGMRDLTASVIEELG-EVKVHGIAIQPGKPTIIGEI-NGKPVFGLPG 302 DI + +GG S G +D ++E+LG +VK H + I+P KP + G K FGLPG Sbjct: 239 HKYDIFITTGGVSMGEKDYVQYLVEDLGIDVKFHKLRIKPAKPVLFGVYGENKLFFGLPG 298 Query: 303 YPTSCLTNFTLLVVPLLLRALG-REGKVRKVKARLKHKIFSVKG-RRQFLPVKL--EGG- 357 P S F LLV P + G RE +KV A L+ RR+F ++ E G Sbjct: 299 NPVSAAVAFDLLVYPAIKAMQGHREVFKQKVTAILEGDYRRKNADRREFARCRVWFENGR 358 Query: 358 -VAVPILK-GSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLF 399 P K S +TS ++++ ++ + E V + +G+EVEV LF Sbjct: 359 YHCEPYPKQDSHMLTSLVNSNAYMVVYEGVNELKKGQEVEVILF 402 >pir||E82188 molybdopterin biosynthesis MoeA protein VC1527 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9656032|gb|AAF94681.1| (AE004231) molybdopterin biosynthesis MoeA protein [Vibrio cholerae] Length = 606 Score = 217 bits (547), Expect = 2e-55 Identities = 136/410 (33%), Positives = 222/410 (53%), Gaps = 20/410 (4%) Query: 2 AFLKVVPLERALEIVNSFTLPLG-TEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60 AFL V E+ E + S PL TE V + E R++A +++SP ++P + + +DGYA Sbjct: 205 AFLSV---EQGREKILSLISPLAETESVAIQECYQRVLAREVFSPNNVPAYRNSAMDGYA 261 Query: 61 VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120 +R++D S +VV E+ AG +++GE V I TGA +P AD V+ E Sbjct: 262 LRSDDLERDS------YRVVAEVLAGSHYPKTVERGEAVKIMTGAPMPLGADTVVMREQA 315 Query: 121 ERVGDEIIIYKPAY--PGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVF 178 + G E++ + A G V + G D+++G+ + G+R+ + +L+++G F Sbjct: 316 TQNG-ELVSFAGAKIKAGQNVRQAGEDLAQGQAVFSIGQRVLSPEMGMLASLGFAHADAF 374 Query: 179 RKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKE 238 R KVAI STG+E+ PG +++P I+D N L+ + +LG + I LGI DD + + Sbjct: 375 RSLKVAIFSTGDEVQAPGGDIEPNSIFDSNRFTLTGLLKQLGCQVIDLGIIEDDEAKMMQ 434 Query: 239 LIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVF 298 ++E+ + AD+V+ SGG S G D S +E+LG++ I ++PG+P G+I GKP F Sbjct: 435 VLEQAAKQADVVITSGGVSVGDADFIKSALEKLGQIDFWRINMRPGRPLAFGQIAGKPFF 494 Query: 299 GLPGYPTSCLTNFTLLVVPLLLRALGREG-KVRKVKARLKHKIFSVKGRRQF----LPVK 353 GLPG P + + +F V P L + G +G + KV A + S +GR +F Sbjct: 495 GLPGNPVAVMVSFINFVEPALRKMQGEQGWQPLKVNAIALEDLRSRQGRTEFSRGVYAFN 554 Query: 354 LEGGVAVPIL--KGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFEG 401 +G + V +GSG + S +A+ IEI +++V GE V + +G Sbjct: 555 TQGQLTVRTTGKQGSGILRSMSEANCLIEIAPAIDTVKVGESVTIIPLQG 604 >dbj|BAB06740.1| (AP001517) molybdopterin biosynthesis [Bacillus halodurans] Length = 423 Score = 217 bits (546), Expect = 2e-55 Identities = 132/406 (32%), Positives = 220/406 (53%), Gaps = 11/406 (2%) Query: 7 VPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDT 66 +P+ A+E V +F E V L EA GR +A+ + + ++PPFD++ +DG+A+RA DT Sbjct: 8 IPVHEAVEQVVAFAKERAMEWVPLEEADGRFLAQPLVADHNVPPFDKSPLDGFAIRAVDT 67 Query: 67 FMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFE---DVERV 123 A+ P++LK++ EI AG+ + +GE + I TGA +P+ DAV+ FE ++ Sbjct: 68 EDATRETPVRLKIIEEIGAGQVAQKVPSQGEAIRIMTGAQMPEGTDAVVMFELTKEISEA 127 Query: 124 GDEIIIYKPAY-PGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPK 182 G+ I K ++ PG + G D +G LV KG ++ ALL+ G +V V++ PK Sbjct: 128 GESFIEVKRSFQPGDNISFCGEDAKEGTPLVEKGRQIDAGIKALLATFGYAKVPVYKMPK 187 Query: 183 VAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEE 242 + I +TG E++ L PG+I + N ++ V ++G E ++LG DD + + I Sbjct: 188 IGIFATGTELLEVDEPLVPGKIRNSNAYMVASQVKQIGAEPVYLGKLVDDFDQCYDAIAT 247 Query: 243 GVRVADIVVISGGASGGMRDLTASVIEELG-EVKVHGIAIQPGKPTIIGEINGKPVFGLP 301 + D++V +GG S G D ++ E+LG V + IA++PG T + E G+ +FGL Sbjct: 248 ALADVDVLVTTGGVSVGDYDYLPAIYEKLGANVLFNKIAMRPGSVTTVAEREGQLLFGLS 307 Query: 302 GYPTSCLTNFTLLVVPLL-LRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAV 360 G P++C F LLV P + + + +++VKA L +F+ ++E + Sbjct: 308 GNPSACFVGFELLVRPFIHVGFCSEQPFLKRVKATLGRDFPKPNPFTRFVRSQVEFKIDR 367 Query: 361 PILK-----GSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFEG 401 I+K SG VTS +A+G + +P G+EV+V L +G Sbjct: 368 LIVKPTGLDKSGVVTSLANANGLLMLPGGTRGFQAGDEVDVLLLKG 413 >sp|P12281|MOEA_ECOLI MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|78705|pir||A32352 molybdopterin biosynthesis protein moeA - Escherichia coli >gi|145539|gb|AAA23579.1| (M21151) chlE protein [Escherichia coli] >gi|1651376|dbj|BAA35515.1| (D90720) Molybdopterin biosynthesis MoeA protein. [Escherichia coli] >gi|1651379|dbj|BAA35522.1| (D90721) Molybdopterin biosynthesis MoeA protein. [Escherichia coli] >gi|1787049|gb|AAC73914.1| (AE000185) molybdopterin biosynthesis [Escherichia coli K12] Length = 411 Score = 215 bits (543), Expect = 5e-55 Identities = 142/403 (35%), Positives = 212/403 (52%), Gaps = 14/403 (3%) Query: 6 VVPLERALEIVNSFTLPLGTEE-VKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAE 64 ++ L+ AL + S PL +E + L + GRI+A D+ SP+D+P FD + +DGYAVR Sbjct: 7 LMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDVVSPLDVPGFDNSAMDGYAVRLA 66 Query: 65 DTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVG 124 D A+ L V G+ AG+ E G + I TGA +P+ +AV+ E E++ Sbjct: 67 DI-----ASGQPLPVAGKSFAGQPYHGEWPAGTCIRIMTGAPVPEGCEAVVMQEQTEQMD 121 Query: 125 DEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVA 184 + + G + ++G DIS G ++ G RL + +++++G+ V V RK +VA Sbjct: 122 NGVRFTAEVRSGQNIRRRGEDISAGAVVFPAGTRLTTAELPVIASLGIAEVPVIRKVRVA 181 Query: 185 IISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGV 244 + STG+E+ LPG L GQIYD N A+ + +LG E I LGI RDD +L+ E Sbjct: 182 LFSTGDELQLPGQPLGDGQIYDTNRLAVHLMLEQLGCEVINLGIIRDDPHALRAAFIEAD 241 Query: 245 RVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYP 304 AD+V+ SGG S G D T +++EELGE+ +AI+PGKP G+++ GLPG P Sbjct: 242 SQADVVISSGGVSVGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSWFCGLPGNP 301 Query: 305 TSCLTNFTLLVVPLLLRALGR--EGKVRKVKARLKHKIFSVKGRRQF----LPVKLEGGV 358 S F LV PLL + G G + + R ++ GR F L +G + Sbjct: 302 VSATLTFYQLVQPLLAKLSGNTASGLPARQRVRTASRLKKTPGRLDFQRGVLQRNADGEL 361 Query: 359 AVPIL--KGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLF 399 V +GS +SF + FI + +V+ GE VEV F Sbjct: 362 EVTTTGHQGSHIFSSFSLGNCFIVLERDRGNVEVGEWVEVEPF 404 >emb|CAC12152.1| (AL445066) molybdopterin biosynthesis protein (moeA-2) related protein [Thermoplasma acidophilum] Length = 399 Score = 210 bits (529), Expect = 2e-53 Identities = 119/402 (29%), Positives = 215/402 (52%), Gaps = 16/402 (3%) Query: 1 MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60 M F + P A+ + + + + V ++E++GR + D+ SP+D P DR+ VDG A Sbjct: 1 MEFKSLTPYGEAIRMASGLRINVRESYVSVAESVGRYCSRDVVSPVDFPEADRSAVDGIA 60 Query: 61 VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120 +R ED+ AS +NPI+L +VGE+ G+ P + +GE + TG+ +P+ A+AV+ ED Sbjct: 61 LRYEDSLSASRSNPIQLSLVGEVRIGDSPAFRINRGECAIVYTGSPIPEGANAVLMKEDA 120 Query: 121 ERVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRK 180 + +Y+ + + G D+ +G ++++G R+ G+++V V Sbjct: 121 SIGKSMVSVYRQMKKFQNISRAGEDLKRGDTIIKRGSRIMPWHLPAFIESGIDKVPVM-D 179 Query: 181 PKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELI 240 ++ I+STG EIV G + + + L ++ +G + F G DD ++ +I Sbjct: 180 AEIGIVSTGTEIV-------RGLVKNSSAPMLEAMISRMGLKSAFYGNVEDDESRIRSVI 232 Query: 241 EEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGL 300 EG++ +DI++++GG+ +DL +I G++ HG+ ++PG+ T +G ++GKPVF + Sbjct: 233 -EGMK-SDIIIVTGGSGPSSQDLVHDIIASNGQLIFHGVRMKPGRTTGLGMMDGKPVFMI 290 Query: 301 PGYPTSCLTNFTLLVVPLLLRALGREGKVRKV-KARLKHKIFSVKGRRQFLPVKL---EG 356 G P + L F ++ P + G + R+ + L IF+ + R F+ V++ +G Sbjct: 291 SGLPVAALIAFENIIDPAIRSWFGMKSLERRTRRGYLTRSIFNNENMRMFVRVRMFEEDG 350 Query: 357 GVAVPILK--GSGAVTSFIDADGFIEIPETVESVDEGEEVEV 396 V ++ GSG + S I ADG++ I E E EG EV+V Sbjct: 351 KTMVEPMRTTGSGVINSVISADGYLVIEENSEGYPEGAEVDV 392 >sp|Q39054|CNX1_ARATH MOLYBDOPTERIN BIOSYNTHESIS CNX1 PROTEIN (MOLYBDENUM COFACTOR BIOSYNTHESIS ENZYME CNX1) >gi|1263314|gb|AAA97413.1| (L47323) molybdenum cofactor biosynthesis enzyme [Arabidopsis thaliana] >gi|4469123|emb|CAB38312.1| (AJ236870) molybdenum cofactor biosynthesis enzyme [Arabidopsis thaliana] Length = 670 Score = 202 bits (509), Expect = 5e-51 Identities = 144/425 (33%), Positives = 213/425 (49%), Gaps = 38/425 (8%) Query: 5 KVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAE 64 +++P E AL IV + L V L EALG+++AEDI +P +PP+ + DGYAV A Sbjct: 15 EMIPTEEALRIVFGVSKRLPPVIVSLYEALGKVLAEDIRAPDPLPPYPASVKDGYAVVAS 74 Query: 65 DTFMASEANPIKLKVVGEIHAGEEPK-LELKKGETVYISTGAMLPKNADAVIQFEDVERV 123 D P + V+ E AG + + + G Y++TG +P ADAV+Q ED + + Sbjct: 75 D-------GPGEYPVITESRAGNDGLGVTVTPGTVAYVTTGGPIPVGADAVVQVEDTKVI 127 Query: 124 GD------EIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRV 177 GD + I G + + G DI K ++ GER+G + LL+ GV V+V Sbjct: 128 GDVSTEAKRVKILIQTKKGTDIRRVGCDIEKDATVLTTGERIGASEIGLLATAGVTMVKV 187 Query: 178 FRKPKVAIISTGNEIVLP-GSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESL 236 + P VAI+STG+E+V P L GQI D N L AV + + + LGI RDDR+ L Sbjct: 188 YPMPIVAILSTGDELVEPTAGTLGRGQIRDSNRAMLVAAVMQQQCKVVDLGIVRDDRKEL 247 Query: 237 KELIEEGVRV-ADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGK 295 +++++E V DI++ SGG S G RD ++EE G+V + ++PGKP EI K Sbjct: 248 EKVLDEAVSSGVDIILTSGGVSMGDRDFVKPLLEEKGKVYFSKVLMKPGKPLTFAEIRAK 307 Query: 296 P----------VFGLPGYPTSCLTNFTLLVVPLLLRALG-REGKVRKVKARLKHKIFSVK 344 P FGLPG P SCL F + VVP + + G +V+ RL+ I S Sbjct: 308 PTESMLGKTVLAFGLPGNPVSCLVCFNIFVVPTIRQLAGWTSPHPLRVRLRLQEPIKSDP 367 Query: 345 GRRQF----LPVKLEGGVAVP--ILKGSG-----AVTSFIDADGFIEIPETVESVDEGEE 393 R +F + K G P + + +G + S A+ +E+P T + G Sbjct: 368 IRPEFHRAIIKWKDNDGSGTPGFVAESTGHQMSSRLLSMRSANALLELPATGNVLSAGSS 427 Query: 394 VEVTL 398 V + Sbjct: 428 VSAII 432 >sp|P45210|MOEA_HAEIN MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|1075033|pir||B64124 molybdopterin biosynthesis protein moeA - Haemophilus influenzae (strain Rd KW20) >gi|1574287|gb|AAC23098.1| (U32823) molybdopterin biosynthesis protein (moeA) [Haemophilus influenzae Rd] Length = 404 Score = 200 bits (504), Expect = 2e-50 Identities = 130/395 (32%), Positives = 204/395 (50%), Gaps = 14/395 (3%) Query: 14 EIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEAN 73 +++ P TE + L EA RI AEDI SPI++P FD + +DGYAVR D + Sbjct: 10 KMLEQLPFPTQTEYLNLQEAANRICAEDIISPINVPSFDNSAMDGYAVRLSDLQQS---- 65 Query: 74 PIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPA 133 + L V G+ AG + E V I TGAM+P+ DAVI E V D I + Sbjct: 66 -LTLSVAGKSFAGNPFQEEWPSKSAVRIMTGAMIPEGTDAVIMQEQVTLNEDGTITFSEL 124 Query: 134 -YPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEI 192 P + + G D+ KG +++ +G +L LL+++G+ V+ +R+ KV ++STG+E+ Sbjct: 125 PKPNQNIRRIGEDVKKGDVVLEQGAQLTPVSLPLLASLGIAEVKCYRQLKVGVLSTGDEL 184 Query: 193 VLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVI 252 V G L+ GQIYD N + + +L E I LG+ D+ ++ AD+V+ Sbjct: 185 VEVGKPLQSGQIYDTNRFTVKLLLEKLHCEVIDLGLLPDNEAEFEKAFIAAQSQADLVIT 244 Query: 253 SGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFT 312 SGG S G D T +V+E++G+V IAI+PGKP G++ GLPG P S L F Sbjct: 245 SGGVSVGEADFTKAVLEKVGQVNFWKIAIKPGKPFAFGKLENAWFCGLPGNPVSALVTFY 304 Query: 313 LLVVPLLLRALGREGKVRK------VKARLKHKIFSVKGRRQFLPVKLEGGVAVPIL--K 364 LV PL+ + G++ + LK + + +R F + +G + V + + Sbjct: 305 QLVQPLIAKLQGQKQWKKPPHFSAIATMNLKKAVGRLDFQRGFYYINEQGQIEVQSVGFQ 364 Query: 365 GSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLF 399 GS ++F+ ++ FI + + +V GE V + F Sbjct: 365 GSHLFSAFVKSNCFIVLEQERGNVSAGETVTIEPF 399 >pir||C83266 molybdenum cofactor biosynthesis protein A2 PA3028 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9949132|gb|AAG06416.1|AE004728_2 (AE004728) molybdenum cofactor biosynthesis protein A2 [Pseudomonas aeruginosa] Length = 405 Score = 200 bits (504), Expect = 2e-50 Identities = 142/391 (36%), Positives = 213/391 (54%), Gaps = 17/391 (4%) Query: 9 LERALEIVNSFTLPLGT-EEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTF 67 LER LE+ P+ T E+V L +A GR++A D+ + +D+PP+ + +DGYA+R D Sbjct: 17 LERLLELAAQ--TPIDTCEQVPLEQAGGRVLAVDLLAGLDLPPWPNSAMDGYALRLADW- 73 Query: 68 MASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEI 127 N L V +I AG+ PK L+ G I TGA LP+ AD V E+ E + D Sbjct: 74 -----NGEPLPVSQKIFAGQAPK-PLQAGTCARIFTGAPLPEGADLVEMQENAEALDDGR 127 Query: 128 IIY-KPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAII 186 + + +P G V +G +I +G L++ G RL + L +++G + V RKP+VA++ Sbjct: 128 VRFTQPLRVGQHVRPRGQEIRQGDLVLPAGTRLRSIELGLAASLGYAALEVRRKPRVALL 187 Query: 187 STGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRV 246 STG+E+V G L+ GQIY+ N L D + LG + + GI DD +E + G+ Sbjct: 188 STGDELVEAGQPLQAGQIYNSNRPLLKDWLQRLGCDVLDAGILPDDLARTRERLA-GLAG 246 Query: 247 ADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTS 306 D+++ +GG S G D + E GE+ + +AI+PGKP +G+ G PV GLPG P S Sbjct: 247 VDLILSTGGVSVGEADFLGMALREAGELTLWKLAIKPGKPLTVGQFQGIPVIGLPGNPAS 306 Query: 307 CLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKG--RRQFLPVKLEGGVAVPI-L 363 L F LL P LLR LG +V ++ + K RR++L +LE G AV Sbjct: 307 TLVTFALLARPYLLRRLG-VAQVAPLRVEVPAGFAWTKAGQRREYLRGRLEQGRAVLYPN 365 Query: 364 KGSGAVTSFIDADGFIEIPETVESVDEGEEV 394 + SG + S A+G +E+ E ++ EGE V Sbjct: 366 QSSGVLRSASWAEGLVEVREG-RTLVEGEGV 395 >pir||E82439 molybdopterin biosynthesis MoeA protein VCA0617 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9658029|gb|AAF96518.1| (AE004391) molybdopterin biosynthesis MoeA protein [Vibrio cholerae] Length = 435 Score = 198 bits (499), Expect = 8e-50 Identities = 139/404 (34%), Positives = 202/404 (49%), Gaps = 16/404 (3%) Query: 6 VVPLERALEIVNSFTLPLGTE-EVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAE 64 ++P+E AL+ + S P+ T + L EALG ++AE I SPI +PPFD + +DGYAVR Sbjct: 33 LMPIEDALKKMLSRIQPVQTTLRLPLPEALGYVLAEAILSPIHVPPFDNSAMDGYAVRR- 91 Query: 65 DTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVG 124 A A L V G+ AG+ + V I TGA +P DAVI E + Sbjct: 92 ----AELAQQKPLPVAGKSFAGQPFTADWPPMTCVRIMTGAQIPAGCDAVIMQEQAT-IT 146 Query: 125 DEIIIYKPAYPGLG--VMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPK 182 +E +++ L + G DI + +++ +G RL + +++ +G+ V V+RKPK Sbjct: 147 EEGVVFCQHEVKLNDNIRPTGDDIRQNDVVLERGARLTARDIPMIATLGISHVTVYRKPK 206 Query: 183 VAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEE 242 VA STG+E+ G L+ GQIYD N + + G E I LGI D +LK E+ Sbjct: 207 VAFFSTGDELKPLGEPLQAGQIYDSNRYGIKPLIENFGCEAIDLGIVPDCPATLKATFEQ 266 Query: 243 GVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPG 302 +AD+VV SGG S G D T ++EELGE+ +AI+PGKP G + GLPG Sbjct: 267 AQSLADVVVTSGGVSVGEADYTKDILEELGEIGFWKLAIKPGKPFAFGALQDAWFCGLPG 326 Query: 303 YPTSCLTNFTLLVVPLLLRALGREG--KVRKVKARLKHKIFSVKGRRQFLP--VKLEGGV 358 P S + +LV P+L + G + A + GR F ++E G Sbjct: 327 NPVSAVLTMYVLVQPMLAKLAGHSAWQAPESIPAITRSPFKKAPGRTDFQRGIYRIENGQ 386 Query: 359 AVPILKG---SGAVTSFIDADGFIEIPETVESVDEGEEVEVTLF 399 V G SGA S A+ F+ + V+ GE V++ LF Sbjct: 387 FVVESTGNQSSGAFRSMSLANCFVVLERERGRVEVGETVQIQLF 430 >dbj|BAA92623.1| (AB037806) KIAA1385 protein [Homo sapiens] Length = 768 Score = 198 bits (497), Expect = 1e-49 Identities = 136/425 (32%), Positives = 214/425 (50%), Gaps = 41/425 (9%) Query: 1 MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60 M+ + +++A V T LGTE + + +GR++A+D+Y+ ++PPF + DGYA Sbjct: 350 MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYA 409 Query: 61 VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120 VRA D P ++GE AGE+P + G+ + ++TGA +P ADAV+Q ED Sbjct: 410 VRAAD-------GPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDT 462 Query: 121 ERVGD--------EIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGV 172 E + + E+ I A PG + G DI +G ++ KG +G + LL+ VGV Sbjct: 463 ELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGV 522 Query: 173 ERVRVFRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDD 232 V V + P VA++STGNE++ P +L PG+I D N L + E G I LGI D+ Sbjct: 523 TEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDN 582 Query: 233 RESLKELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVH--GIAIQPGKPTIIG 290 + L + EG+ AD+++ SGG S G +D V++ ++H + ++PG PT Sbjct: 583 PDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFA 642 Query: 291 --EING--KPVFGLPGYPTSCLTNFTLLVVPLLLRALG-REGKVRKVKARLK-------- 337 +I+G K +F LPG P S + L VVP L + G + + +KARL Sbjct: 643 TLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPR 702 Query: 338 ---HKIFSVKGRRQFLPVKLEGGVAVPILKGSGAVTSFIDADGFIEIPETVE---SVDEG 391 H+ ++ LP G + S + S A+G + +P E + +G Sbjct: 703 PEYHRCILTWHHQEPLPWAQSTGNQM-----SSRLMSMRSANGLLMLPPKTEQYVELHKG 757 Query: 392 EEVEV 396 E V+V Sbjct: 758 EVVDV 762 >gb|AAF81785.1|AF272663_1 (AF272663) gephyrin [Homo sapiens] Length = 736 Score = 198 bits (497), Expect = 1e-49 Identities = 136/425 (32%), Positives = 214/425 (50%), Gaps = 41/425 (9%) Query: 1 MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60 M+ + +++A V T LGTE + + +GR++A+D+Y+ ++PPF + DGYA Sbjct: 318 MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYA 377 Query: 61 VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120 VRA D P ++GE AGE+P + G+ + ++TGA +P ADAV+Q ED Sbjct: 378 VRAAD-------GPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDT 430 Query: 121 ERVGD--------EIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGV 172 E + + E+ I A PG + G DI +G ++ KG +G + LL+ VGV Sbjct: 431 ELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGV 490 Query: 173 ERVRVFRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDD 232 V V + P VA++STGNE++ P +L PG+I D N L + E G I LGI D+ Sbjct: 491 TEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDN 550 Query: 233 RESLKELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVH--GIAIQPGKPTIIG 290 + L + EG+ AD+++ SGG S G +D V++ ++H + ++PG PT Sbjct: 551 PDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFA 610 Query: 291 --EING--KPVFGLPGYPTSCLTNFTLLVVPLLLRALG-REGKVRKVKARLK-------- 337 +I+G K +F LPG P S + L VVP L + G + + +KARL Sbjct: 611 TLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPR 670 Query: 338 ---HKIFSVKGRRQFLPVKLEGGVAVPILKGSGAVTSFIDADGFIEIPETVE---SVDEG 391 H+ ++ LP G + S + S A+G + +P E + +G Sbjct: 671 PEYHRCILTWHHQEPLPWAQSTGNQM-----SSRLMSMRSANGLLMLPPKTEQYVELHKG 725 Query: 392 EEVEV 396 E V+V Sbjct: 726 EVVDV 730 >gi|10880983 gephyrin; gephryin [Homo sapiens] >gi|10636475|emb|CAC10537.1| (AJ272343) gephyrin [Homo sapiens] Length = 769 Score = 198 bits (497), Expect = 1e-49 Identities = 136/425 (32%), Positives = 214/425 (50%), Gaps = 41/425 (9%) Query: 1 MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60 M+ + +++A V T LGTE + + +GR++A+D+Y+ ++PPF + DGYA Sbjct: 351 MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYA 410 Query: 61 VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120 VRA D P ++GE AGE+P + G+ + ++TGA +P ADAV+Q ED Sbjct: 411 VRAAD-------GPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDT 463 Query: 121 ERVGD--------EIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGV 172 E + + E+ I A PG + G DI +G ++ KG +G + LL+ VGV Sbjct: 464 ELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGV 523 Query: 173 ERVRVFRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDD 232 V V + P VA++STGNE++ P +L PG+I D N L + E G I LGI D+ Sbjct: 524 TEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDN 583 Query: 233 RESLKELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVH--GIAIQPGKPTIIG 290 + L + EG+ AD+++ SGG S G +D V++ ++H + ++PG PT Sbjct: 584 PDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFA 643 Query: 291 --EING--KPVFGLPGYPTSCLTNFTLLVVPLLLRALG-REGKVRKVKARLK-------- 337 +I+G K +F LPG P S + L VVP L + G + + +KARL Sbjct: 644 TLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPR 703 Query: 338 ---HKIFSVKGRRQFLPVKLEGGVAVPILKGSGAVTSFIDADGFIEIPETVE---SVDEG 391 H+ ++ LP G + S + S A+G + +P E + +G Sbjct: 704 PEYHRCILTWHHQEPLPWAQSTGNQM-----SSRLMSMRSANGLLMLPPKTEQYVELHKG 758 Query: 392 EEVEV 396 E V+V Sbjct: 759 EVVDV 763 >sp|Q03555|GEPH_RAT GEPHYRIN (PUTATIVE GLYCINE RECEPTOR-TUBULIN LINKER PROTEIN) >gi|111656|pir||JH0681 gephyrin - rat >gi|56312|emb|CAA47009.1| (X66366) Gephyrin [Rattus norvegicus] Length = 736 Score = 198 bits (497), Expect = 1e-49 Identities = 136/425 (32%), Positives = 214/425 (50%), Gaps = 41/425 (9%) Query: 1 MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60 M+ + +++A V T LGTE + + +GR++A+D+Y+ ++PPF + DGYA Sbjct: 318 MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYA 377 Query: 61 VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120 VRA D P ++GE AGE+P + G+ + ++TGA +P ADAV+Q ED Sbjct: 378 VRAAD-------GPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDT 430 Query: 121 ERVGD--------EIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGV 172 E + + E+ I A PG + G DI +G ++ KG +G + LL+ VGV Sbjct: 431 ELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGV 490 Query: 173 ERVRVFRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDD 232 V V + P VA++STGNE++ P +L PG+I D N L + E G I LGI D+ Sbjct: 491 TEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDN 550 Query: 233 RESLKELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVH--GIAIQPGKPTIIG 290 + L + EG+ AD+++ SGG S G +D V++ ++H + ++PG PT Sbjct: 551 PDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFA 610 Query: 291 --EING--KPVFGLPGYPTSCLTNFTLLVVPLLLRALG-REGKVRKVKARLK-------- 337 +I+G K +F LPG P S + L VVP L + G + + +KARL Sbjct: 611 TLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPR 670 Query: 338 ---HKIFSVKGRRQFLPVKLEGGVAVPILKGSGAVTSFIDADGFIEIPETVE---SVDEG 391 H+ ++ LP G + S + S A+G + +P E + +G Sbjct: 671 PEYHRCILTWHHQEPLPWAQSTGNQM-----SSRLMSMRSANGLLMLPPKTEQYVELHKG 725 Query: 392 EEVEV 396 E V+V Sbjct: 726 EVVDV 730 >gi|11435181 gephyrin [Homo sapiens] Length = 419 Score = 198 bits (497), Expect = 1e-49 Identities = 136/425 (32%), Positives = 214/425 (50%), Gaps = 41/425 (9%) Query: 1 MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60 M+ + +++A V T LGTE + + +GR++A+D+Y+ ++PPF + DGYA Sbjct: 1 MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYA 60 Query: 61 VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120 VRA D P ++GE AGE+P + G+ + ++TGA +P ADAV+Q ED Sbjct: 61 VRAAD-------GPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDT 113 Query: 121 ERVGD--------EIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGV 172 E + + E+ I A PG + G DI +G ++ KG +G + LL+ VGV Sbjct: 114 ELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGV 173 Query: 173 ERVRVFRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDD 232 V V + P VA++STGNE++ P +L PG+I D N L + E G I LGI D+ Sbjct: 174 TEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDN 233 Query: 233 RESLKELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVH--GIAIQPGKPTIIG 290 + L + EG+ AD+++ SGG S G +D V++ ++H + ++PG PT Sbjct: 234 PDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFA 293 Query: 291 --EING--KPVFGLPGYPTSCLTNFTLLVVPLLLRALG-REGKVRKVKARLK-------- 337 +I+G K +F LPG P S + L VVP L + G + + +KARL Sbjct: 294 TLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPR 353 Query: 338 ---HKIFSVKGRRQFLPVKLEGGVAVPILKGSGAVTSFIDADGFIEIPETVE---SVDEG 391 H+ ++ LP G + S + S A+G + +P E + +G Sbjct: 354 PEYHRCILTWHHQEPLPWAQSTGNQM-----SSRLMSMRSANGLLMLPPKTEQYVELHKG 408 Query: 392 EEVEV 396 E V+V Sbjct: 409 EVVDV 413 >pir||G70829 probable molybdenum cofactor biosynthesis protein - Mycobacterium tuberculosis (strain H37RV) >gi|2909513|emb|CAA17395.1| (AL021932) moaA3 [Mycobacterium tuberculosis] Length = 405 Score = 196 bits (493), Expect = 4e-49 Identities = 123/379 (32%), Positives = 197/379 (51%), Gaps = 10/379 (2%) Query: 28 VKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIHAGE 87 V L++A G ++ D+ +P+ +P FD + +DGYAVRAEDT A+ NP+ L V +I AG Sbjct: 23 VPLTQAQGLVLGGDVVAPLSLPVFDNSAMDGYAVRAEDTSGATPQNPVMLPVAEDIPAGR 82 Query: 88 EPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAYPGLGVMKKGVDIS 147 L L+ I TGA +P A A++ E + D + I + A PG + + G D++ Sbjct: 83 ADMLTLQPVTAHRIMTGAPVPTGATAIVPVEATDGGVDSVAIRQQATPGKHIRRSGEDVA 142 Query: 148 KGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELKPGQIYDI 207 G ++ G+ + L +A+G+ + V + +V +ISTG+E+ PG+ L+PGQIY+ Sbjct: 143 AGTTVLHNGQIVTPAVLGLAAALGLAELPVLPRQRVLVISTGSELASPGTPLQPGQIYES 202 Query: 208 NGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISGGASGG----MRDL 263 N L+ AV + G + A DD +++ AD+++ SGG S G ++D Sbjct: 203 NSIMLAAAVRDAGAAVVATATAGDDVAQFGAILDRYAVDADLIITSGGVSAGAYEVVKDA 262 Query: 264 TASVIEELGE--VKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFTLLVVPLLLR 321 S G+ V+ +A+QPG P +G + G P+ LPG P S L +F + + P L Sbjct: 263 FGSADYRGGDHGVEFVKVAMQPGMPQGVGRVAGTPIVTLPGNPVSALVSFEVFIRPPLRM 322 Query: 322 ALGREGKVRKVK-ARLKHKIFSVKGRRQFLPVKLEGGVAVPILKGSGA---VTSFIDADG 377 A+G R + A L + S +G+RQF L+ I G A + A+G Sbjct: 323 AMGLPDPYRPHRSAVLTASLTSPRGKRQFRRAILDHQAGTVISYGPPASHHLRWLASANG 382 Query: 378 FIEIPETVESVDEGEEVEV 396 ++IPE V V G +++V Sbjct: 383 LLDIPEDVVEVAAGTQLQV 401 >emb|CAA67416.1| (X98917) orf5 [Methanopyrus kandleri] Length = 408 Score = 195 bits (491), Expect = 7e-49 Identities = 132/381 (34%), Positives = 202/381 (52%), Gaps = 18/381 (4%) Query: 10 ERALEIVNSFTLPLGTEEVKLSEAL-GRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFM 68 E + + F P E V++ L GR++AED+ + PPF R+ +DGYAVR+ED Sbjct: 19 EEFIRFLRRFLSPPEPETVEVGPELSGRVLAEDVRAERPSPPFTRSAMDGYAVRSED--- 75 Query: 69 ASEANP-IKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEI 127 A P +LKVVGE GE +++ GE VY+ TGA +P+ ADAVI E VER GDEI Sbjct: 76 ---AEPGARLKVVGESRIGEGTDVKVGPGEAVYVDTGAPVPEGADAVIPVEFVERDGDEI 132 Query: 128 IIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIIS 187 I+ + PG + G + +G +L R G + ++ GVE V V R +V+I+ Sbjct: 133 IVEEGVDPGDNLDPAGCYVEEGEVLYRSGHLVEPVDVGVMLEHGVEEVDVHRPLRVSIVV 192 Query: 188 TGNEIVLPGSELK-PGQIYDINGRALSDAVNELG-GEGIFLGIARDDRESLKELIEEGVR 245 TGNE+V SEL+ Q+ D G L+ + +G E + + +DD ++E +E+ Sbjct: 193 TGNELVHRPSELESETQVVDCIGPVLTAELENMGCVEVVGTSLVKDDPGEIRETVEDYAD 252 Query: 246 VADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPT 305 +D+V+I+GG+S G RD ++++ + +HGI +PG+P I G F LPG+PT Sbjct: 253 RSDVVLITGGSSVGERDHVKDILDDTFDAFIHGIRARPGRPFGIAAREGTVAFTLPGWPT 312 Query: 306 SCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQ---FLPVKLEGGVAVPI 362 SC + F + VVP LL G + V + + +K +R+ V+L A + Sbjct: 313 SCYSTFRVWVVPSLLVLAGADPLV----VGFETEATGIKSKREVGVIARVRLTSDGAEGL 368 Query: 363 LKG-SGAVTSFIDADGFIEIP 382 + S F + DGF +P Sbjct: 369 SRDRSSHFALFRETDGFALVP 389 >pir||E69659 molybdopterin biosynthesis protein moeA - Bacillus subtilis >gi|2633799|emb|CAB13301.1| (Z99111) molybdopterin biosynthesis protein [Bacillus subtilis] >gi|3282112|gb|AAC24902.1| (AF012285) molybdopterin biosynthesis protein MoeA [Bacillus subtilis] Length = 430 Score = 192 bits (484), Expect = 4e-48 Identities = 135/416 (32%), Positives = 205/416 (48%), Gaps = 37/416 (8%) Query: 7 VPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDT 66 +P++ A+ V F TE V L ++L R +AEDI + +P FDR+ DG+AVRA DT Sbjct: 8 IPVDEAVRRVCHFQKQGETEWVALEDSLHRFLAEDITADHHVPAFDRSPYDGFAVRACDT 67 Query: 67 FMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFE---DVERV 123 AS NP++ +V+ I AG + EL + V I TGA +P+ ADAV+ E E Sbjct: 68 AEASRENPVRFEVIDHIGAGAVSEKELGPFQAVRIMTGAQIPEGADAVVMIELTQAFEEN 127 Query: 124 GDEIIIYKPAY-PGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPK 182 G + K + G + K G D KG +L+ KG R+ TALL+ G V V RKP Sbjct: 128 GKSFMSLKRRFQTGDNISKTGEDAQKGSVLLTKGTRVTPGVTALLATFGYASVPVVRKPV 187 Query: 183 VAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEE 242 V II+TG E++ L+PG+I + N + E G ++LG D+ + ++E Sbjct: 188 VGIIATGTELLNVSDPLEPGKIRNSNASMVYAQAIEAGATPLYLGKISDELDKSFAAVKE 247 Query: 243 GVRVADIVVISGGASGGMRDLTASVIEELG-EVKVHGIAIQPGKPTIIGEINGKPVFGLP 301 ++ D ++ +GG S G D ++ E+LG +V + +A++PG T + N +FGL Sbjct: 248 AMKKVDFLITTGGVSVGDFDFLPAIYEKLGADVLFNKVAMRPGSVTTVAHANDMLLFGLS 307 Query: 302 GYPTSCLTNFTLLVVPLLLRALGREGK-------------------VRKVKARLKHKIFS 342 G P++C F L V P++ L E R V+A + H+ Sbjct: 308 GNPSACYVGFELFVKPIIQTWLLNETPHSICAEAVLTKDFPKPNPFTRFVRALVHHQ--- 364 Query: 343 VKGRRQFLPVKLEGGVAVPILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTL 398 +G+ PV L+ S +VTS DA+ FI +P + G V+V L Sbjct: 365 -EGKLLATPVGLD---------KSSSVTSLADANAFIILPGGTRGYESGRTVQVLL 410 >gb|AAC83139.1| (AF109295) MoeA [Staphylococcus carnosus] Length = 419 Score = 191 bits (481), Expect = 1e-47 Identities = 125/401 (31%), Positives = 204/401 (50%), Gaps = 7/401 (1%) Query: 7 VPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDT 66 +P+ A++ V + + V L+++LG ++AEDI + +IP F+++ DG+A+R+EDT Sbjct: 9 IPVREAIKRVVEQDIETEVQNVPLNKSLGYVLAEDIVATYEIPRFNKSPYDGFALRSEDT 68 Query: 67 FMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDE 126 AS N I+ +V+ I AG + + V I TGA +P ADAV+ E + Sbjct: 69 VGASGDNRIEFEVIDHIGAGSVSDKTVGPNQAVRIMTGAEVPAGADAVVMLEQTKEGDHT 128 Query: 127 IIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAII 186 I K V KG + G ++++KG+R+ A+L+ G V V + P AII Sbjct: 129 FTIRKTFSHNENVSLKGEETEVGDVVLKKGQRINAGGIAVLATFGYTEVPVRKLPSAAII 188 Query: 187 STGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRV 246 +TG+E++ G EL+PG+I + NG + +N+ G +G I DD ES ++++ + Sbjct: 189 ATGSELLDVGDELEPGKIRNSNGPMIEGLLNQFGLDGEVYKIQEDDLESSIAVVKQAMET 248 Query: 247 ADIVVISGGASGGMRDLTASVIEEL-GEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPT 305 D+V+ +GG S G D + + L EV + + ++PG T + +GK +FGL G P+ Sbjct: 249 HDMVITTGGVSVGDFDYLPEIYKALDAEVLFNKVQMRPGSVTTVAVAHGKYLFGLSGNPS 308 Query: 306 SCLTNFTLLVVPLLLRALGREGKV-RKVKARLKHKIFSVKGRRQFLPVK--LEGGVAVPI 362 +C T F L V +L +G K + VKA L +F+ K L G A + Sbjct: 309 ACYTGFQLFVKTGVLNMMGANEKFPQVVKATLMEDFKKANPFTRFIRSKATLNGMEATVV 368 Query: 363 LKG---SGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFE 400 G SGAV + ++ + +P G V+V L E Sbjct: 369 PSGFNKSGAVVAIAHSNAMVMLPSGTRGFHAGNTVDVILTE 409 >sp|Q44243|MOEA_ANASP MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|1002858|gb|AAC44505.1| (U34309) moeA gene product [Anabaena sp.] Length = 436 Score = 190 bits (477), Expect = 3e-47 Identities = 112/304 (36%), Positives = 164/304 (53%), Gaps = 5/304 (1%) Query: 25 TEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIH 84 TE V L A GRI+A + S +D P +D + +DGYAVR ED ++ P+ L+VV EI Sbjct: 48 TEIVDLWAANGRILATPVNSTLDFPHWDNSAMDGYAVRYEDVHNSNAEQPVSLEVVAEIP 107 Query: 85 AGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAYPGLGVMKKGV 144 AG +PK L+ G+ I TGA++P D V+ E + + + I PG V K Sbjct: 108 AGYQPKFTLQPGQAARIFTGAVMPSGGDTVVMQEKTRQENNRVFILTTPKPGEFVRLKAA 167 Query: 145 DISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELKPGQI 204 G L+ +L + A+L+A +V+V+R+P+VAI STG+E+V L+PGQI Sbjct: 168 YYQAGTQLLPANTQLNAAEIAILAASQCPQVKVYRRPRVAIFSTGDELVTLDQPLQPGQI 227 Query: 205 YDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISGGASGGMRDLT 264 D N AL+ V + G E I GI +D+ +L E I + + ADIV+ SGG S G D Sbjct: 228 VDSNQYALAALVKQNGAEPILFGIVKDNPTALGETISKAIANADIVISSGGVSVGDYDYV 287 Query: 265 ASVIEELG-EVKVHGIAIQPGKPTIIGEINGKPV---FGLPGYPTSCLTNFTLLVVPLLL 320 ++ LG ++ + + ++PGKP + P GLPG P + L F V P ++ Sbjct: 288 DQILASLGAKIHIRSVEMRPGKPLTVATFPTPPAPIYLGLPGNPAAVLVTFWRFVQP-VI 346 Query: 321 RALG 324 R LG Sbjct: 347 RKLG 350 >sp|O05577|MOEA_MYCTU MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|7445251|pir||E70601 probable MoeAprotein - Mycobacterium tuberculosis (strain H37RV) >gi|2052128|emb|CAB08154.1| (Z94752) moeA [Mycobacterium tuberculosis] Length = 426 Score = 187 bits (471), Expect = 1e-46 Identities = 128/397 (32%), Positives = 203/397 (50%), Gaps = 28/397 (7%) Query: 28 VKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIK----------- 76 V ++EA G + AE++ + +P FD+A +DGYAVR+ D + ++ Sbjct: 23 VAIAEAQGLMCAEEVVTERPMPGFDQAAIDGYAVRSVDVAGVGDTGGVQVFADHGDLDGR 82 Query: 77 ----LKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKP 132 L V+G I AG L+ + V + TGA LP ADAV+ + + + + Sbjct: 83 DVLTLPVMGTIEAGARTLSRLQPRQAVRVQTGAPLPTLADAVLPLRWTDGGMSRVRVLRG 142 Query: 133 AYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEI 192 A G V + G D+ G + VR G +G Q LL+AVG ERV V +P++++++ G E+ Sbjct: 143 APSGAYVRRAGDDVQPGDVAVRAGTIIGAAQVGLLAAVGRERVLVHPRPRLSVMAVGGEL 202 Query: 193 VLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVI 252 V GQ+YD+N AL+ A + E +GI +D L E++E + A++VVI Sbjct: 203 VDISRTPGNGQVYDVNSYALAAAGRDACAEVNRVGIVSNDPTELGEIVEGQLNRAEVVVI 262 Query: 253 SGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEI--NGKPVFGLPGYPTSCLTN 310 +GG G + SV+ ELGE++V +A+ PG G++ +G P F LP P S L Sbjct: 263 AGGVGGAAAEAVRSVLSELGEMEVVRVAMHPGSVQGFGQLGRDGVPTFLLPANPVSALVV 322 Query: 311 FTLLVVPLLLRALGREGKVRK-VKARLKHKIFSVKGRRQFLPVKL-----EGGVAVPILK 364 F ++V PL+ +LG+ +R+ V AR I SV GR+ +L +L G V L Sbjct: 323 FEVMVRPLIRLSLGKRHPMRRIVSARTLSPITSVAGRKGYLRGQLMRDQDSGEYLVQALG 382 Query: 365 GSGAVTSFI-----DADGFIEIPETVESVDEGEEVEV 396 G+ +S + +A+ + +P E + GE V+V Sbjct: 383 GAPGASSHLLATLAEANCLVVVPTGAEQIRTGEIVDV 419 >pir||T45454 probable molybdenum cofactor biosynthesis protein [imported] - Mycobacterium leprae >gi|4455711|emb|CAB36697.1| (AL035500) putative molybdenum cofactor biosynthesis protein [Mycobacterium leprae] Length = 424 Score = 187 bits (470), Expect = 2e-46 Identities = 129/395 (32%), Positives = 204/395 (50%), Gaps = 26/395 (6%) Query: 28 VKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANP------------- 74 V ++EA G + AE++ + +P FD+A +DGYAVR+ D E++ Sbjct: 23 VAIAEAQGLMCAEEVMTERPLPGFDQAAIDGYAVRSVDVSGIGESDGGESGSSDEDGRYV 82 Query: 75 IKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAY 134 + L V+G I AG L + V + TGA LP ADAV+ + + I + A Sbjct: 83 LTLPVMGTIEAGARTPSRLLPHQAVRVQTGAPLPVLADAVLPVRWTDGGMSRVRILRGAP 142 Query: 135 PGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVL 194 G V + G D+ G + VR G +G Q LL+AVG ERV V +P+++I++ G E+V Sbjct: 143 SGAYVRRVGDDVQPGDVAVRAGTIIGAAQVGLLAAVGRERVLVHPRPRLSIMAVGGELVD 202 Query: 195 PGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISG 254 GQ+YD+N AL+ A + G E +GI ++ + E++E + A++VVI+G Sbjct: 203 ISRTPGNGQVYDVNSYALTAAGRDAGAEVNRIGIVSNNLKEFGEVVEGQISRAEVVVIAG 262 Query: 255 GASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEI--NGKPVFGLPGYPTSCLTNFT 312 G G + +V+ E+GE++V +A+ PG G++ G P F LP P S L F Sbjct: 263 GVGGAAAEAVRAVLSEIGEMEVVRVAMHPGSVQGFGQLGREGVPTFLLPANPVSALVVFE 322 Query: 313 LLVVPLLLRALGREGKVRK-VKARLKHKIFSVKGRRQFLPVKL-----EGGVAVPILKGS 366 ++V PL+ +LG+ +R+ V+AR I SV GR+ +L +L G V L G+ Sbjct: 323 VMVRPLIRLSLGKRQPMRRIVQARTLSPITSVAGRKGYLRGQLMRDQDTGEYLVQALGGA 382 Query: 367 GAVTSFI-----DADGFIEIPETVESVDEGEEVEV 396 +S + +A+ + IP E + GE V+V Sbjct: 383 LGASSHLLATLAEANCLVVIPSGAEQIRTGEVVDV 417 >sp|Q56066|MOEA_SALTY MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|1256834|gb|AAA96529.1| (U53178) moeA gene product [Salmonella typhimurium] Length = 412 Score = 185 bits (466), Expect = 6e-46 Identities = 139/400 (34%), Positives = 201/400 (49%), Gaps = 17/400 (4%) Query: 6 VVPLERALEIVNSFTLPL-GTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAE 64 ++PLE AL + S PL E + L GRI+A DI SP+D+P FD + +DGYAVR Sbjct: 9 LMPLETALTQMLSRITPLTAVETLPLVNCFGRILATDIVSPLDVPGFDNSAMDGYAVRVA 68 Query: 65 DTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVG 124 D S P L V G+ AG+ + E G + I TGA +P +AV+ E E+ Sbjct: 69 DL---SADKP--LPVAGKAFAGQPYQGEWPAGTCIRIMTGAPVPAGCEAVVMQEQTEQTD 123 Query: 125 DEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVA 184 D G + ++G DI + ++ G RL + +L+++G+ +V RK +VA Sbjct: 124 DGERFTADVRCGQNIRRRGEDIRQDAVVFPAGTRLTTAELPVLASLGIADAQVVRKVRVA 183 Query: 185 IISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGG-EGIFLGIARDDRESLKELIEEG 243 + STG+E+ LPG L+ QIYD N + + +LG E I LGI DD L+ I+ Sbjct: 184 LFSTGDELQLPGQPLEADQIYDTNRLTIHLMLQQLGWREVINLGIIPDDPGKLRGFIDAD 243 Query: 244 VRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGY 303 + AD VVIS S G D T +++EELGE+ +AI+PGKP G+++ GLPG Sbjct: 244 SQ-AD-VVISSRVSEGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSWFCGLPGN 301 Query: 304 PTSCLTNFTLLVVPLLLRALGREGKV--RKVKARLKHKIFSVKGRRQF----LPVKLEGG 357 P S F LV PLL + G + + R ++ GR F L G Sbjct: 302 PVSAALTFYQLVQPLLAKLGGNTASAVPPRQRVRTASRLKKTPGRLDFQRGILQRSANGE 361 Query: 358 VAVPIL--KGSGAVTSFIDADGFIEIPETVESVDEGEEVE 395 + V +GS +SF + FI + +V+ GE VE Sbjct: 362 LEVTTTGHQGSHIFSSFSLGNCFIVLERERGNVEPGEWVE 401 >gb|AAD49748.1|AF174130_1 (AF174130) gephyrin [Gallus gallus] Length = 736 Score = 183 bits (459), Expect = 4e-45 Identities = 117/351 (33%), Positives = 184/351 (52%), Gaps = 22/351 (6%) Query: 1 MAFLKVVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYA 60 M+ + +++A V T LGTE + + +GR++A+D+Y+ ++PPF + DGYA Sbjct: 318 MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYA 377 Query: 61 VRAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDV 120 VRA D P ++GE AGE+P + G+ + ++TGA +P ADAV+Q ED Sbjct: 378 VRAAD-------GPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDT 430 Query: 121 ERVGD--------EIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGV 172 E + + E+ I A PG + G DI +G ++ KG G + LL+ VGV Sbjct: 431 ELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHTGPSEVGLLATVGV 490 Query: 173 ERVRVFRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDD 232 V V + P VA++STGNE++ P ++ PG+I D N L + G I LGI D+ Sbjct: 491 TEVEVNKFPVVAVMSTGNELLNPEDDVLPGKIRDSNRSTLLATIQAHGYPTINLGIVGDN 550 Query: 233 RESLKELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVH--GIAIQPGKPTIIG 290 + L + E + AD+++ SGG S G + V++ ++H + ++PG PT Sbjct: 551 PDDLLNALNERISRADVIITSGGVSMGGKYYLKQVLDIDLHAQIHFGRVFMKPGLPTTFA 610 Query: 291 --EING--KPVFGLPGYPTSCLTNFTLLVVPLLLRALG-REGKVRKVKARL 336 +I+G K +F LPG S + L VVP L + G + + +KARL Sbjct: 611 TLDIDGVRKIIFALPGQSVSAVVTCNLFVVPALRKMQGILDPRPTIIKARL 661 >pir||B75562 molybdopterin biosynthesis MoeA - Deinococcus radiodurans (strain R1) >gi|6457741|gb|AAF09669.1|AE001871_1 (AE001871) molybdopterin biosynthesis MoeA [Deinococcus radiodurans] Length = 401 Score = 181 bits (455), Expect = 1e-44 Identities = 137/379 (36%), Positives = 194/379 (51%), Gaps = 21/379 (5%) Query: 30 LSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIHAGEEP 89 L +ALG + D+ + + P + +DG A R DT AS P+ L+VVGE AGE Sbjct: 33 LRKALGCTLGADLTALVSHPSATESALDGIACREADTLTASAGAPVALRVVGESRAGEPF 92 Query: 90 KLELKKGETVYISTGAMLPKNADAVIQFED---------VERVGDEIIIYKPAYPGLGVM 140 E+ GE V I TGA LP DA+ E VER E++ +PA PG V Sbjct: 93 AGEVGPGECVRIYTGAPLPPGTDAICPVEQLREGEGTSAVERGTVELL--RPARPG-DVR 149 Query: 141 KKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELK 200 +G D G ++ G RL + AL +A+G +V V R+ +VA++STG+E+V PG L Sbjct: 150 PEGGDFHAGETVMSAGLRLTPARLALAAALGHAQVPV-RRWRVALLSTGDEVVAPGQPLA 208 Query: 201 PGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISGGASGGM 260 PGQ+YD N L+ + E G E + LG A D +L+E + AD+++ SGG S G Sbjct: 209 PGQVYDSNRVGLAALLTEAGYEVLDLGHAPDSPAALRERL-GAAGGADLLLTSGGVSMGR 267 Query: 261 RDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFTLLVVPLLL 320 D ++ GE+ + ++PG P + G G PVFGLPG P S L F ++V P+L Sbjct: 268 YDFMRDLLLGEGEITFWKVKMRPGGPALCGRWGGLPVFGLPGNPVSSLVVFQVIVRPVL- 326 Query: 321 RALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGG-VAVPILKGSGAVTSFIDADGFI 379 G R+V A S+ + F L G V +GSG + S DAD + Sbjct: 327 --TGEPLPTRQVTAAT--PFASLADKTAFWRGVLSGDEVRDYPRQGSGVLRSLSDADALV 382 Query: 380 EIPETVESVDEGEEVEVTL 398 +PE +++ GE VEV L Sbjct: 383 VVPEG-QNIAAGERVEVVL 400 >gb|AAF73075.1|AF268595_1 (AF268595) molybdenum cofactor biosynthesis protein Cnx1 [Hordeum vulgare] Length = 659 Score = 180 bits (453), Expect = 2e-44 Identities = 119/341 (34%), Positives = 180/341 (51%), Gaps = 26/341 (7%) Query: 28 VKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIHAGE 87 V L +ALG ++AED +P +PPF + DGYAV A D P + V+ E AG+ Sbjct: 25 VPLLDALGLVLAEDARAPDPLPPFRASVKDGYAVVAAD-------GPGEYPVIAEARAGD 77 Query: 88 EPK-LELKKGETVYISTGAMLPKNADAVIQFEDVERV-----GDEIIIYKPAYP-GLGVM 140 + + + G Y++TG +P ADAV+Q ED E+V G + + P G + Sbjct: 78 DALGVVVTPGTVAYVTTGGPIPDGADAVVQVEDTEQVAAAPDGSKRVRISARVPEGHDIR 137 Query: 141 KKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPG-SEL 199 G DI K ++++ GE +G + LL+ VGV V+ +R+P +A+ STG+E+V P + L Sbjct: 138 SVGCDIEKDSIVLKSGENIGPAEIGLLATVGVTTVKAYRRPTIAVFSTGDELVEPATATL 197 Query: 200 KPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRV-ADIVVISGGASG 258 GQI D N L A + + + LGIA+D ESL E ++ + ADI++ SGG S Sbjct: 198 NRGQIRDSNRAMLLAAAIQQKCKVVDLGIAKDTEESLMEHMDAALHSDADIILTSGGVSM 257 Query: 259 GMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEING----KP-----VFGLPGYPTSCLT 309 G RDL + ++G++ I ++PGKP EI KP FGLPG P SC+ Sbjct: 258 GDRDLVKPCLAKMGKIHFEKIRMKPGKPLTFAEITSNDTTKPSKTALAFGLPGNPVSCMV 317 Query: 310 NFTLLVVPLLLRALG-REGKVRKVKARLKHKIFSVKGRRQF 349 F + VVP + G +++V R+ H + + R +F Sbjct: 318 CFNVFVVPAIRLVSGWSNPHLQRVHVRISHPLRADPHRMEF 358 >pir||H83155 molybdenum cofactor biosynthetic protein A1 PA3914 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9950098|gb|AAG07301.1|AE004809_1 (AE004809) molybdenum cofactor biosynthetic protein A1 [Pseudomonas aeruginosa] Length = 407 Score = 179 bits (449), Expect = 6e-44 Identities = 124/378 (32%), Positives = 194/378 (50%), Gaps = 9/378 (2%) Query: 8 PLERAL-EIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDT 66 PL+ AL E++ P E + L ALGR++ ED+ +P+D+P +D + +DGYA+ + D Sbjct: 13 PLDEALAELLARAPRPPACESLALERALGRVLGEDLLAPMDLPHWDNSAMDGYALCSADL 72 Query: 67 FMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDE 126 + + L V I AG+ + L G+ I TGA LP AD V+ +++ V E Sbjct: 73 PRSGGS----LTVGARIAAGDTRGMSLPLGQAARIFTGAPLPTGADCVVP-QELCVVDGE 127 Query: 127 IIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAII 186 + P G V ++G ++ +G ++R G+RL ++ LL+++GV V V R+ ++ ++ Sbjct: 128 RVQLPPVSAGQHVRRRGEELRRGAPVLRAGQRLRPQELGLLASLGVATVSVRRRLRIGLL 187 Query: 187 STGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRV 246 S+G+E+ PG L GQIY+ N + + LG E + D+ + ++ + Sbjct: 188 SSGDELREPGQTLLAGQIYNANRYCIGALLRGLGFEVHDEEVLADELVASRDALSLAASE 247 Query: 247 ADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTS 306 D +V SGG S G D I ELGEV + +AIQPGKP G + GKP GLPG P + Sbjct: 248 WDALVTSGGVSVGEEDHLKRAIAELGEVNLWRLAIQPGKPFAFGSVAGKPWLGLPGNPAA 307 Query: 307 CLTNFTLLVVPLLLRALGREGKV-RKVKARLKHKIFSVKGRRQFLPVKLE--GGVAVPIL 363 L L+ P LLR G V R + + RRQ+L +L+ G V + Sbjct: 308 ALVTALLVARPFLLRQQGLFDVVPRPLALPAAFDWPQPRARRQYLRARLDERGRVEIHPQ 367 Query: 364 KGSGAVTSFIDADGFIEI 381 +GS + + ADG I Sbjct: 368 QGSAMLLAASWADGLAVI 385 >pir||T46858 molybdenum cofactor biosynthesis protein A [imported] - Rhodobacter sphaeroides >gi|4185549|gb|AAD09121.1| (AF108766) molybdenum cofactor biosynthesis protein A [Rhodobacter sphaeroides] Length = 394 Score = 176 bits (443), Expect = 3e-43 Identities = 118/320 (36%), Positives = 167/320 (51%), Gaps = 10/320 (3%) Query: 6 VVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAED 65 ++ +E AL + PL E V L EA GR++A + D PPFD + +DGYA+ + Sbjct: 1 MISVEEALARALALAAPLPVERVALGEARGRVMARPALATRDQPPFDASAMDGYALIGDP 60 Query: 66 TFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGD 125 A+ VVGE AG + L+ GE V I TGA +P+ A V+ EDV G Sbjct: 61 PAGAT------FPVVGEAAAGHGYEGALRPGEAVRIFTGAPVPEGATRVVLQEDVTAEGG 114 Query: 126 EIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAI 185 I + A G + +G D G L + RL ALL+A+ + V V R+P VA+ Sbjct: 115 TIRLNAAATGGTHIRPRGQDFRTGDSLSPR--RLRPNDLALLAAMNIPEVTVTRRPSVAL 172 Query: 186 ISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVR 245 I+TG+E+V+PG +P QI N AL V G E L IARD + L+ +++ Sbjct: 173 IATGDELVMPGEVPRPDQIVASNSFALKALVEAEGAEARLLPIARDTEDELRTVLDL-AS 231 Query: 246 VADIVVISGGASGGMRDLTASVIEELG-EVKVHGIAIQPGKPTIIGEINGKPVFGLPGYP 304 AD++V GGAS G DL V +G E + IA++PGKP + G + G P+ GLPG P Sbjct: 232 DADLIVTIGGASVGDHDLVGKVAAGMGLERAFYKIAMRPGKPLMAGRLRGVPMLGLPGNP 291 Query: 305 TSCLTNFTLLVVPLLLRALG 324 S + L ++P+L LG Sbjct: 292 VSSIVCAHLFLLPMLRAMLG 311 >pir||G71966 molybdopterin biosynthesis protein - Helicobacter pylori (strain J99) >gi|4154674|gb|AAD05741.1| (AE001454) MOLYBDOPTERIN BIOSYNTHESIS PROTEIN [Helicobacter pylori J99] Length = 390 Score = 167 bits (419), Expect = 2e-40 Identities = 121/410 (29%), Positives = 207/410 (49%), Gaps = 36/410 (8%) Query: 6 VVPLERALEIVNSFTL-PLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAE 64 ++ + AL+I ++ L PL E V L E+ GRI+AEDI +P F+++ +DGY + + Sbjct: 1 MISFKEALKIHSNIPLKPLEVEVVSLFESAGRILAEDIICVHALPKFNQSAMDGYGFKMQ 60 Query: 65 DTFMASEANPIKLKVVGEIHAGEEPK-LELKKGETVYISTGAMLPKNADAVIQFEDV-ER 122 D K +V+ I AG++ LE+K+ E V I TGAM+PK + ++ E + E Sbjct: 61 DLGQ-------KTQVIQHIFAGDDVSALEVKENECVKIMTGAMVPKGIETIVPIECMLES 113 Query: 123 VGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPK 182 D + K + +KG + S +LV K RL + AL+++ G + ++ FRK K Sbjct: 114 HKDFALAPKDFKIHANIRQKGENASLNSVLVPKNTRLNYGHIALIASQGFKEIKAFRKLK 173 Query: 183 VAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEE 242 +A+ S+G+E+V G Q+YD+N + + + FLG+ +DD+ +++E Sbjct: 174 IALFSSGDELVPLGQNALECQVYDVNSVGVFNMLKNYNTH--FLGVLKDDKNLQLKILE- 230 Query: 243 GVRVADIVVISGGASGGMRDLTASVIEELGEVKVH-GIAIQPGKPTIIGEINGKPVFGLP 301 ++ D+++ S G S G +D ++E + + + ++PGKP + ++N + GLP Sbjct: 231 -LQGYDVILSSAGVSVGDKDFFKDALKERNALFYYEKVNLKPGKPVTLAQLNQSIIIGLP 289 Query: 302 GYPTSCLTNFTLLVVPLLLR-ALGREGKVRKVKARLK----------HKIFSVKGRRQFL 350 G P SCL +L++PLL R +L ++ K++ KA++ H I QF+ Sbjct: 290 GNPLSCLLVLRVLILPLLERLSLNKDFKLKPFKAQINAPLKLNNKRTHLILGNYSNHQFI 349 Query: 351 PVKLEGGVAVPILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFE 400 P SGA+ + D I E V V E+E+ FE Sbjct: 350 PYNNR--------YESGAIQALAQVDSIALIDEGVGLVQ--GEIEILRFE 389 >pir||D64541 molybdopterin biosynthesis protein - Helicobacter pylori (strain 26695) >gi|2313255|gb|AAD07237.1| (AE000537) molybdopterin biosynthesis protein (moeA) [Helicobacter pylori 26695] Length = 391 Score = 167 bits (418), Expect = 2e-40 Identities = 120/410 (29%), Positives = 207/410 (50%), Gaps = 35/410 (8%) Query: 6 VVPLERALEIVNSFTL-PLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAE 64 ++ + AL+I +S + PL E + L E++GRI+AEDI +P F+++ +DGY + + Sbjct: 1 MISFKEALKIHSSIPIKPLEIEVISLFESIGRILAEDIICIHALPKFNQSAMDGYGFKMQ 60 Query: 65 DTFMASEANPIKLKVVGEIHAGEEPK-LELKKGETVYISTGAMLPKNADAVIQFEDV-ER 122 D K +VV I AG++ LE+K+ E V I TGAM+PK + ++ E + E Sbjct: 61 DLGK-------KTQVVQRIFAGDDVSALEVKENECVKIMTGAMVPKGIETIVPIECMLES 113 Query: 123 VGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPK 182 + + K + +KG + S +LV K RL + AL+++ G++ ++ FRK K Sbjct: 114 HTNFALAPKDFKINANIRQKGENASLNSVLVPKNTRLNYGHIALIASQGLKEIKAFRKLK 173 Query: 183 VAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEE 242 +A+ S+G+E+V G Q+YD+N + + + FLG+ +DD+ +++E Sbjct: 174 IALFSSGDELVPLGQNALECQVYDVNSVGIFNMLKNYNTH--FLGVLKDDKNLQLKILES 231 Query: 243 GVRVADIVVISGGASGGMRDLTASVIEELGEVKVH-GIAIQPGKPTIIGEINGKPVFGLP 301 + D+++ S G S G +D ++E + + + ++PGKP + +N + GLP Sbjct: 232 --QDYDVILSSAGVSVGDKDFFKDALKEKNALFYYEKVNLKPGKPVTLARLNQSMIIGLP 289 Query: 302 GYPTSCLTNFTLLVVPLLLR-ALGREGKVRKVKARLK----------HKIFSVKGRRQFL 350 G P SCL +L++PLL R +L ++ K++ KA++ H I QF+ Sbjct: 290 GNPLSCLLVLRVLILPLLERLSLNKDFKLKPFKAQINAPLKLKGERAHLILGNYSNHQFI 349 Query: 351 PVKLEGGVAVPILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEVTLFE 400 P SGA+ + D I E V V E+E+ FE Sbjct: 350 PYNNN-------RYDSGAIQALARVDSIALIDEGVRLVQ--GEIEILRFE 390 >pir||T44851 molybdopterin co-factor synthesis protein moeA [imported] - Arthrobacter nicotinovorans plasmid pAO1 >gi|4469094|emb|CAA71780.2| (Y10817) molybdopterin co-factor synthesis protein [Arthrobacter nicotinovorans] Length = 430 Score = 163 bits (408), Expect = 4e-39 Identities = 105/307 (34%), Positives = 156/307 (50%), Gaps = 18/307 (5%) Query: 22 PLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVG 81 P E + L +A+GR +AE I++P ++PPF + +DGYAVR+ DT L+V Sbjct: 50 PPRVERIPLMQAMGRGLAETIHAPTNLPPFTNSQMDGYAVRSRDTAGGQGG----LRVAA 105 Query: 82 EIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVG---------DEIIIYKP 132 I AG P L G I TGA++P ADAV+ VER D + Sbjct: 106 PIPAGAVPA-PLVGGTAAQIMTGALIPDGADAVVP---VERAVPNHFPPPGLDRTVRLPE 161 Query: 133 AYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEI 192 G + G DI+ G + G LG +Q LL+A+G+ V V +K V + +TG+E+ Sbjct: 162 IAAGTYIRSAGSDIATGECALSAGTVLGPRQLGLLAALGITEVVVNQKLTVLLATTGDEV 221 Query: 193 VLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVI 252 + PG +L G+IYD N L ++ + G I GI +D+ +L +L+ D++V Sbjct: 222 LEPGEKLALGKIYDANNTLLQSSMLQAGLNVIRAGIVKDEPGALSKLLRSHTAHVDLIVT 281 Query: 253 SGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFT 312 SGG S G + + + +V+ +AIQPG P +G G PV PG P SC +F Sbjct: 282 SGGVSAGAYEPVRQAMID-HDVEFSHVAIQPGGPQGVGTFEGIPVLAFPGNPVSCFVSFE 340 Query: 313 LLVVPLL 319 + + PLL Sbjct: 341 MFLRPLL 347 >gb|AAK40978.1| Molybdopterin biosynthesis protein (moeA-1) [Sulfolobus solfataricus] Length = 389 Score = 162 bits (407), Expect = 5e-39 Identities = 110/395 (27%), Positives = 201/395 (50%), Gaps = 12/395 (3%) Query: 4 LKVVPLERALEIVNSFTLPLGTEE--VKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAV 61 + ++P+E A +I+++ + E V++ +ALG+I EDI + +P + +DGYA+ Sbjct: 1 MALIPVEEARKIISNTNFEVKRREKYVEIFQALGKIAVEDILAVKSMPERSLSAMDGYAI 60 Query: 62 RAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVE 121 + +D KL+VVG+++ ELK+GET Y++TG+ LP AD+V+ E+ Sbjct: 61 KYDDYLKYG-----KLRVVGKLYPSTSNIPELKEGETYYVTTGSPLPLYADSVVPVENSR 115 Query: 122 RVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKP 181 G+ +I G + ++G DI+ G+++++KG + +L + V+V Sbjct: 116 LEGEYVIFKGEVKKGKNIREEGEDINIGQIIIQKGTEITPYYLGILIQQKIFHVKV-SDL 174 Query: 182 KVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIE 241 K + + G+EI + K I I+ + + E G ++G+A+DD + E IE Sbjct: 175 KFTVFANGDEITSFENPQKNKIIDSISPILIK--ILEKFGSVKYMGVAKDDLNDVTEKIE 232 Query: 242 EGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLP 301 + + ++D+++ GG+S G +D + +LGEV G+++ K +G I GKP+ LP Sbjct: 233 KSLEISDVIISVGGSSVGEKDYVKKAVNKLGEVLFDGVSVNTIKRGSVGRIQGKPILILP 292 Query: 302 GYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAVP 361 G S +T F + +L LG K + +K+ L I+ ++G A P Sbjct: 293 GQVVSAITAFHEFGLSVLSNILGTNLK-KFIKSTLVEDIYVNHSMDSVYLFNVKGNSAFP 351 Query: 362 ILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEV 396 + G G + A+GF + + + +GEEVE+ Sbjct: 352 LRWGVGLYSELAKANGFAILKRGL-TYKKGEEVEL 385 >emb|CAB57627.1| (Y18930) molybdopterin biosynthesis protein [Sulfolobus solfataricus] Length = 389 Score = 162 bits (407), Expect = 5e-39 Identities = 110/395 (27%), Positives = 201/395 (50%), Gaps = 12/395 (3%) Query: 4 LKVVPLERALEIVNSFTLPLGTEE--VKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAV 61 + ++P+E A +I+++ + E V++ +ALG+I EDI + +P + +DGYA+ Sbjct: 1 MALIPVEEARKIISNTNFEVKRREKYVEIFQALGKIAVEDILAVKSMPERSLSAMDGYAI 60 Query: 62 RAEDTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVE 121 + +D KL+VVG+++ ELK+GET Y++TG+ LP AD+V+ E+ Sbjct: 61 KYDDYLKYG-----KLRVVGKLYPSTSNIPELKEGETYYVTTGSPLPLYADSVVPVENSR 115 Query: 122 RVGDEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKP 181 G+ +I G + ++G DI+ G+++++KG + +L + V+V Sbjct: 116 LEGEYVIFKGEVKKGKNIREEGEDINIGQIIIQKGTEITPYYLGILIQQKIFHVKV-SDL 174 Query: 182 KVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIE 241 K + + G+EI + K I I+ + + E G ++G+A+DD + E IE Sbjct: 175 KFTVFANGDEITSFENPQKNKIIDSISPILIK--ILEKFGSVKYMGVAKDDLNDVTEKIE 232 Query: 242 EGVRVADIVVISGGASGGMRDLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLP 301 + + ++D+++ GG+S G +D + +LGEV G+++ K +G I GKP+ LP Sbjct: 233 KSLEISDVIISVGGSSVGEKDYVKKAVNKLGEVLFDGVSVNTIKRGSVGRIQGKPILILP 292 Query: 302 GYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAVP 361 G S +T F + +L LG K + +K+ L I+ ++G A P Sbjct: 293 GQVVSAITAFHEFGLSVLSNILGTNLK-KFIKSTLVEDIYVNHSMDSVYLFNVKGNSAFP 351 Query: 362 ILKGSGAVTSFIDADGFIEIPETVESVDEGEEVEV 396 + G G + A+GF + + + +GEEVE+ Sbjct: 352 LRWGVGLYSELAKANGFAILKRGL-TYKKGEEVEL 385 >emb|CAA04211.1| (AJ000662) MoeA protein [Wolinella succinogenes] Length = 410 Score = 160 bits (400), Expect = 3e-38 Identities = 112/395 (28%), Positives = 187/395 (46%), Gaps = 15/395 (3%) Query: 9 LERALEIVNSFTLPLG-TEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTF 67 L +A+ I+ P+ L + G+I+A+D++ +P FD + +DGYAVR D Sbjct: 7 LRKAISIMLEHANPIHRVHYTHLFDLTGKILAQDLFCQKALPAFDNSGMDGYAVRLADLG 66 Query: 68 MASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEI 127 K ++G I AGE + L G + TGA +P AVI FE+ D Sbjct: 67 Q-------KTPILGTILAGESCSVGLHDGACYKVMTGAPIPLGTQAVIPFENATLKDDST 119 Query: 128 IIYKPAYP-GLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAII 186 ++ + G + G ++ G L++KGERL ALL++ G + + ++ + Sbjct: 120 VLLPTDFKEGANIKIAGEELQVGAPLLQKGERLTHHHVALLASQGYSVLPTYAPLRIGVY 179 Query: 187 STGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRV 246 S+GNE++ P + QIY+ N L + G +LG+ D E ++E I G Sbjct: 180 SSGNELIEPWESAQSHQIYNSNASMLFSTLQNFGWRADYLGVLPDCLEGMREAIR-GFDA 238 Query: 247 ADIVVISGGASGGMRDLTASVIEELGEVKV-HGIAIQPGKPTIIGEINGKPVFGLPGYPT 305 D+++ +GG S G D +EE G + HGI ++PG+PT++G + + LPG P Sbjct: 239 YDVILTTGGVSQGEADFMERSLEEAGMTTLFHGIEVKPGRPTMMGILGKTTLLCLPGNPL 298 Query: 306 SCLTNFTLLVVPLLLRALG-REGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAVPILK 364 S N L +P+L + G R + V A K ++ R + +L G + Sbjct: 299 SASINLHFLGIPMLKKMQGERRYHLEFVYAPNKERLILKGNRANMVLGRLHEGCFKATQE 358 Query: 365 ---GSGAVTSFIDADGFIEIPETVESVDEGEEVEV 396 GSG +T ++ I + VE+++EG ++V Sbjct: 359 GKYGSGMLTPLTTSNAIIFCDKGVENLEEGALIKV 393 >sp|Q56207|MOEA_SYNP7 MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|1480150|emb|CAA67944.1| (X99625) moeA [Synechococcus sp.] Length = 403 Score = 159 bits (397), Expect = 7e-38 Identities = 121/389 (31%), Positives = 198/389 (50%), Gaps = 20/389 (5%) Query: 21 LPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVV 80 LPL E V L E R++A+D+ +P D+P +D + +DG+A+R++D AS P++L VV Sbjct: 19 LPLAIERVPLLETGDRLLAKDLAAPCDLPHWDNSAMDGFALRSQDVAAASPDRPVRLPVV 78 Query: 81 GEIHAGEEPKLELK-KGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAYPGLGV 139 G + AGE+P L G + TGA +P D +++ EDV + + I + P G + Sbjct: 79 GRVMAGEQPPLLANPTGVACAVMTGAPIPAGFDVIVKVEDVVQEENAIAVSTPIPAGQFI 138 Query: 140 MKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSE- 198 ++G D+ +G L+ KG+RL L +AVG+ + V+ K V +ISTG E+V P S+ Sbjct: 139 RRQGEDLRQGSPLLAKGQRLTPMALMLAAAVGMGELPVWSKLPVGLISTGTEVV-PWSQP 197 Query: 199 -LKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIE----EGVRVADIVVIS 253 L+ GQI + + L + + LG E + DD E + + +GVR +++ + Sbjct: 198 TLELGQIRNSSQPFLIEQLQRLGCEVRAIAHVPDDPEQFAAIAQQFWSQGVR---LLLTT 254 Query: 254 GGASGGMRDLTASVIEELG-EVKVHGIAIQPGKPTI--IGEINGKPVFGLPGYPTSCLTN 310 G S G+ D + +E LG + H +AI+PGKP + I + V PG P S Sbjct: 255 GAVSMGVADFVPAALERLGCQTIFHKVAIRPGKPLLFAIAPEHQGLVLACPGNPVSTTVT 314 Query: 311 FTLLVVPLLLRALGREGKVRK-VKARLKHKIFSVKGRRQFLPVKL--EGGVAVPILKGSG 367 + PLL+ +VR + L + +G + F +L EG V V + S Sbjct: 315 AEFFLKPLLMAC---RNEVRSPLWLPLAESVRKPEGLQCFWRSRLTPEGKVWVDPQQSSA 371 Query: 368 AVTSFIDADGFIEIPETVESVDEGEEVEV 396 A+ S +++ + +P + + G VEV Sbjct: 372 ALKSLVESTHWAILPAGQDFLAAGTPVEV 400 >pir||A81359 probable molybdopterin biosynthesis protein Cj0857c [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968303|emb|CAB73122.1| (AL139076) putative molybdopterin biosynthesis protein [Campylobacter jejuni] Length = 386 Score = 156 bits (390), Expect = 5e-37 Identities = 109/374 (29%), Positives = 180/374 (47%), Gaps = 17/374 (4%) Query: 25 TEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIH 84 +E + L +A RI+A+D+Y+ ++P FD A +DGYA D A L++ G I Sbjct: 21 SELISLEKAKDRILAKDLYARKNLPSFDNAALDGYAFNYTDINEA-------LEIKGTIF 73 Query: 85 AGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAYPGLGVMKKGV 144 AG++ + K E I TGA +PKNAD ++ ED +++II K KG Sbjct: 74 AGDKNFYTVAKNECYKIMTGAKMPKNADTILMLEDECIEENKLIIKKVPKQYNAYRYKGE 133 Query: 145 DISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELKPGQI 204 ++ KG +L++KG +L K ALL++ G+ ++ V RK ++ I S+GNE+ P E I Sbjct: 134 ELKKGEILLQKGTKLNDKHIALLASQGLYKIEVIRKIRIGIFSSGNELKEPWQECDEESI 193 Query: 205 YDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISGGASGGMRDLT 264 Y+ N L + +LGI +DD +S KE +E D+++ SGGAS G D Sbjct: 194 YNANALPLLTMLQNAS----YLGIIKDDFKSTKEALEN--TNFDLLITSGGASVGEADFM 247 Query: 265 ASVIEELGEVKV-HGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFTLLVVPLLLRAL 323 ++ELG + G+ +P +PT + V LPG P + + + ++ Sbjct: 248 EKALDELGFTPLFKGLKARPARPTKLYRKGENFVLILPGNPMAAYLSCFIFAKKIINLLS 307 Query: 324 GREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAVPILK---GSGAVTSFIDADGFIE 380 G ++ + GR + LE G+ P + GSG + I ++ + Sbjct: 308 GNLDNPLTFYGKMGMDLKLKSGRNNLILGNLEKGIFTPFNENKFGSGMILPLIKSEFLLI 367 Query: 381 IPETVESVDEGEEV 394 E + +G+E+ Sbjct: 368 SEENTGELKKGDEI 381 >emb|CAB57390.1| (AJ238348) MoeA protein [Rhodobacter capsulatus] Length = 459 Score = 151 bits (377), Expect = 2e-35 Identities = 121/416 (29%), Positives = 190/416 (45%), Gaps = 37/416 (8%) Query: 6 VVPLERALEIVNSFTLPLG-TEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAE 64 ++ L+ A + P+G +E + L++A GR A + + I +P R+ +DG+A+R Sbjct: 56 MLDLDSARRLACGLVAPIGDSETLDLAQAAGRTSATSLRAEIALPRAARSAMDGFALRTA 115 Query: 65 DTFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVG 124 D A + L V G + AG + L G + I TGA +P ADAV+ E+V G Sbjct: 116 DLAAA-----LTLPVAGTVAAGMQAP-PLPDGAALRIFTGAQIPAGADAVVPVEEVTETG 169 Query: 125 DEIIIYKPAYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVA 184 E+ + PG + G + G LL+R+G R+ LL++ GV V V R+P++A Sbjct: 170 AEVQLTAAPAPGSHIRAVGSEQPLGGLLLRRGTRIRAHHIGLLASNGVAEVAVVRRPRLA 229 Query: 185 IISTGNEIVLPGSE-LKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEG 243 I+STG+E+ PG+E + D+N L G E GI DD E+ Sbjct: 230 ILSTGDELHRPGAEAASRDTMPDVNRPMLIALAQGAGAEVDDHGILPDDAEATVAKFASL 289 Query: 244 VRVADIVVISGGASGGMRD-LTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPG 302 D++V +G S G RD L ++I G++ +A++PGKP + G + V GLPG Sbjct: 290 QGRYDLIVTTGAVSMGGRDHLRPALIAAGGQIDGWKVALKPGKPVMFGRLGNAAVTGLPG 349 Query: 303 YPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQF-----------LP 351 P S + FTL V ++ ++K + +F GR F P Sbjct: 350 NPFSAMVGFTLFV----------SAQIARLKGAVPAPLFHCAGRAGFDWTRKPDRAEIFP 399 Query: 352 VKLEGGV--AVPILKGSGAVTS-----FIDADGFIEIPETVESVDEGEEVEVTLFE 400 ++L +P++ G TS +ADG +P V G + FE Sbjct: 400 IRLGNREIDGLPVVHRLGEGTSATLFPLAEADGLGFVPAETARVSVGTPICWQTFE 455 >pir||B81299 probable molybdopterin biosynthesis protein Cj1519 [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968943|emb|CAB73939.1| (AL139078) putative molybdopterin biosynthesis protein [Campylobacter jejuni] Length = 396 Score = 148 bits (371), Expect = 8e-35 Identities = 91/295 (30%), Positives = 156/295 (52%), Gaps = 9/295 (3%) Query: 26 EEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIHA 85 E++ L+E LGRI+A+DI +P + P F + +DGYA++ ED + P LK++G A Sbjct: 23 EKIALTECLGRILAQDIKAPKNQPEFPTSAMDGYAIKFED-----QDKP--LKILGLTPA 75 Query: 86 GEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAYPGLGVMKKGVD 145 G P+ ++ G V TG+++ + +D ++ E++ + + I K V G + Sbjct: 76 GTMPQFSVQNGTCVKTFTGSLMSEGSDTLVPVENIRIENNTLFIEKKVPQAFAVRAVGEN 135 Query: 146 ISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELK-PGQI 204 K +L++KG RL + + ALL+ +G + VF KP V ++S+G+EI G L+ P QI Sbjct: 136 YKKDEILLKKGTRLNYSEIALLAELGFFHISVFIKPIVGVLSSGSEIKDLGEALENPAQI 195 Query: 205 YDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISGGASGGMRDLT 264 N A+++ L + + +DD ++ +E ++ DI+V +GG S G D Sbjct: 196 RSSNHIAIANLAKNLNCDTRVFPLLKDDEKATFSTLESALQSCDILVTTGGVSMGDFDFL 255 Query: 265 ASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFTLLVVPLL 319 I+E E+ + I+PG+ I + N K + LPG+P S + F L +L Sbjct: 256 KKAIKEY-EIIIDKADIKPGRHIKIAKANEKFIIALPGFPYSAMVMFNLYTREIL 309 >emb|CAB65851.1| (AL050231) alternatively spliced form [Drosophila melanogaster] Length = 674 Score = 142 bits (355), Expect = 6e-33 Identities = 120/395 (30%), Positives = 197/395 (49%), Gaps = 38/395 (9%) Query: 6 VVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAED 65 ++P++ L I+ + V+ + L +I+ E + +P++IPPF + DGYA+++ Sbjct: 271 MLPVQEVLSIIFN--------TVQKTANLNKILLE-MNAPVNIPPFRASIKDGYAMKSTG 321 Query: 66 TFMASEANPIKLKVVGEIHAGEEPK-LELKKGETVYISTGAMLPKNADAVIQFED----- 119 F ++ +V+G I AG+ P L L + E I+TGA LP AD V+Q ED Sbjct: 322 -FSGTK------RVLGCIAAGDSPNSLPLAEDECYKINTGAPLPLEADCVVQVEDTKLLQ 374 Query: 120 VERVGDEIIIYKPAYP--GLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRV 177 +++ G E ++ P GL V G D+S + + +LL++VG + Sbjct: 375 LDKNGQESLVDILVEPQAGLDVRPVGYDLSTNDRIFPALDPSPVVVKSLLASVGNRLI-- 432 Query: 178 FRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLK 237 KPKVAI+STG+E+ P ++L PG+I+D N L++ + G + + D + K Sbjct: 433 LSKPKVAIVSTGSELCSPRNQLTPGKIFDSNTTMLTELLVYFGFNCMHTCVLSDSFQRTK 492 Query: 238 ELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVH--GIAIQPGKPTIIGEINGK 295 E + E V D V+ SGG S G +D SV+E+L + ++H + I+PGKP K Sbjct: 493 ESLLELFEVVDFVICSGGVSMGDKDFVKSVLEDL-QFRIHCGRVNIKPGKPMTFASRKDK 551 Query: 296 PVFGLPGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKI---FSVKGRRQFLPV 352 FGLPG P S F L +P + A G + + + + L K+ FS+ R +F+ Sbjct: 552 YFFGLPGNPVSAFVTFHLFALPAIRFAAGWD-RCKCSLSVLNVKLLNDFSLDSRPEFVRA 610 Query: 353 KL--EGGVAVPILKG---SGAVTSFIDADGFIEIP 382 + + G + G S + S + AD I +P Sbjct: 611 SVISKSGELYASVNGNQISSRLQSIVGADVLINLP 645 >emb|CAB65852.1| (AL050231) EG:BACR37P7.3 [Drosophila melanogaster] >gi|7290021|gb|AAF45488.1| (AE003417) cin gene product [Drosophila melanogaster] Length = 601 Score = 142 bits (355), Expect = 6e-33 Identities = 120/395 (30%), Positives = 197/395 (49%), Gaps = 38/395 (9%) Query: 6 VVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAED 65 ++P++ L I+ + V+ + L +I+ E + +P++IPPF + DGYA+++ Sbjct: 198 MLPVQEVLSIIFN--------TVQKTANLNKILLE-MNAPVNIPPFRASIKDGYAMKSTG 248 Query: 66 TFMASEANPIKLKVVGEIHAGEEPK-LELKKGETVYISTGAMLPKNADAVIQFED----- 119 F ++ +V+G I AG+ P L L + E I+TGA LP AD V+Q ED Sbjct: 249 -FSGTK------RVLGCIAAGDSPNSLPLAEDECYKINTGAPLPLEADCVVQVEDTKLLQ 301 Query: 120 VERVGDEIIIYKPAYP--GLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRV 177 +++ G E ++ P GL V G D+S + + +LL++VG + Sbjct: 302 LDKNGQESLVDILVEPQAGLDVRPVGYDLSTNDRIFPALDPSPVVVKSLLASVGNRLI-- 359 Query: 178 FRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLK 237 KPKVAI+STG+E+ P ++L PG+I+D N L++ + G + + D + K Sbjct: 360 LSKPKVAIVSTGSELCSPRNQLTPGKIFDSNTTMLTELLVYFGFNCMHTCVLSDSFQRTK 419 Query: 238 ELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVH--GIAIQPGKPTIIGEINGK 295 E + E V D V+ SGG S G +D SV+E+L + ++H + I+PGKP K Sbjct: 420 ESLLELFEVVDFVICSGGVSMGDKDFVKSVLEDL-QFRIHCGRVNIKPGKPMTFASRKDK 478 Query: 296 PVFGLPGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKI---FSVKGRRQFLPV 352 FGLPG P S F L +P + A G + + + + L K+ FS+ R +F+ Sbjct: 479 YFFGLPGNPVSAFVTFHLFALPAIRFAAGWD-RCKCSLSVLNVKLLNDFSLDSRPEFVRA 537 Query: 353 KL--EGGVAVPILKG---SGAVTSFIDADGFIEIP 382 + + G + G S + S + AD I +P Sbjct: 538 SVISKSGELYASVNGNQISSRLQSIVGADVLINLP 572 >sp|P39205|CIN_DROME MOLYBDENUM COFACTOR SYNTHESIS PROTEIN CINNAMON >gi|1079093|pir||S47896 probable molybdopterin biosynthesis protein cinnamon - fruit fly (Drosophila melanogaster) >gi|505312|gb|AAA65877.1| (L19876) molybdenum cofactor [Drosophila melanogaster] Length = 601 Score = 142 bits (354), Expect = 8e-33 Identities = 120/395 (30%), Positives = 197/395 (49%), Gaps = 38/395 (9%) Query: 6 VVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAED 65 ++P++ L I+ + V+ + L +I+ E + +P++IPPF + DGYA+++ Sbjct: 198 MLPVQEVLSIIFN--------TVQKTANLNKILLE-MNAPVNIPPFRASIKDGYAMKSTG 248 Query: 66 TFMASEANPIKLKVVGEIHAGEEPK-LELKKGETVYISTGAMLPKNADAVIQFED----- 119 F ++ +V+G I AG+ P L L + E I+TGA LP AD V+Q ED Sbjct: 249 -FSGTK------RVLGCIAAGDSPNSLPLAEDECYKINTGAPLPLEADCVVQVEDTKLLQ 301 Query: 120 VERVGDEIIIYKPAYP--GLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRV 177 +++ G E ++ P GL V G D+S + + +LL++VG + Sbjct: 302 LDKNGQESLVDILVEPQAGLDVRPVGYDLSTNDRIFPALDPSPVVVKSLLASVGNRLI-- 359 Query: 178 FRKPKVAIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLK 237 KPKVAI+STG+E+ P ++L PG+I+D N L++ + G + + D + K Sbjct: 360 LSKPKVAIVSTGSELCSPRNQLTPGKIFDSNTTMLTELLVYFGFNCMHTCVLSDTFQRTK 419 Query: 238 ELIEEGVRVADIVVISGGASGGMRDLTASVIEELGEVKVH--GIAIQPGKPTIIGEINGK 295 E + E V D V+ SGG S G +D SV+E+L + ++H + I+PGKP K Sbjct: 420 ESLLELFEVVDFVICSGGVSMGDKDFVKSVLEDL-QFRIHCGRVNIKPGKPMTFASRKDK 478 Query: 296 PVFGLPGYPTSCLTNFTLLVVPLLLRALGREGKVRKVKARLKHKI---FSVKGRRQFLPV 352 FGLPG P S F L +P + A G + + + + L K+ FS+ R +F+ Sbjct: 479 YFFGLPGNPVSAFVTFHLFALPAIRFAAGWD-RCKCSLSVLNVKLLNDFSLDSRPEFVRA 537 Query: 353 KL--EGGVAVPILKG---SGAVTSFIDADGFIEIP 382 + + G + G S + S + AD I +P Sbjct: 538 SVISKSGELYASVNGNQISSRLQSIVGADVLINLP 572 >sp|Q55368|MOEA_SYNY3 MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN >gi|7470744|pir||S75715 molybdopterin biosynthesis protein moeA - Synechocystis sp. (strain PCC 6803) >gi|1001210|dbj|BAA10450.1| (D64003) molybdopterin biosynthesis MoeA [Synechocystis sp.] Length = 390 Score = 142 bits (354), Expect = 8e-33 Identities = 112/401 (27%), Positives = 183/401 (44%), Gaps = 32/401 (7%) Query: 6 VVPLERALEIVNSFTLPLGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAED 65 ++ + A+EI+ + G + + + GR++AE I + D PP DR +DG A+ + Sbjct: 1 MISVAAAVEIIQAHWPNFGDTTMDVDGSYGRVLAESIEADRDYPPGDRVMMDGVALAWSE 60 Query: 66 TFMASEANPIKLKVVGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGD 125 K++G + AG + + + TGA+LP+N D VI +E+V + Sbjct: 61 YHQGRR----HFKLLGTVAAGTPQSSLPDQTGCLEVMTGALLPQNCDLVIPYEEVAIADN 116 Query: 126 EIIIYKPAY--PGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKV 183 ++ I P PG V K D G++++ +L ++++ G +VRV +KP++ Sbjct: 117 QVKIINPRQREPGEFVHPKASDCRAGKVILESSSKLNGPAWNIITSFGKTKVRVKQKPRI 176 Query: 184 AIISTGNEIVLPGSELKPGQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEG 243 IISTG+E+V + K Q+ N L ++ G + + L DD+E + ++ Sbjct: 177 QIISTGDELVEITQKPKIHQLRRSNIYGLQVSLQSRGFQNVNLTHLADDKEVIIRHYQKA 236 Query: 244 VRVADIVVISGGASGGMRDLTASVIEELGEVK-VHGIAIQPGKPTIIG--EINGKPVFGL 300 +++ SGG S G D V +LG K +HG+A +PGKP G + + GL Sbjct: 237 KLEYRVLIYSGGISKGKFDYLPEVWSQLGVTKYIHGVAQKPGKPMYFGIDHRSKTVIIGL 296 Query: 301 PGYPTS---CLTNFTLLVVPLLLRALGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGG 357 PG P S CL + L P + A+L K FLPVKL Sbjct: 297 PGNPISSLVCLHRYFLDSAP--------------IYAQLTTDFTFKKDLTYFLPVKLSHT 342 Query: 358 VAVPI------LKGSGAVTSFIDADGFIEIPETVESVDEGE 392 I +K SG + +DGF+E+P+ S GE Sbjct: 343 PQAVIKAEPLPVKNSGEFIALAGSDGFLELPQHQASFQAGE 383 >pir||T20638 hypothetical protein T06H11.4 - Caenorhabditis elegans >gi|3875564|emb|CAA90060.1| (Z49887) contains similarity to Pfam domain: PF00994 (Molybdenum cofactor biosynthesis protein), Score=324.9, E-value=3.1e-94, N=1~cDNA EST yk255f8.5 comes from this gene~cDNA EST yk255f8.3 comes from this gene~cDNA EST yk561c5.3 comes from this gene~c> >gi|3879587|emb|CAA90069.1| (Z49889) contains similarity to Pfam domain: PF00994 (Molybdenum cofactor biosynthesis protein), Score=324.9, E-value=3.1e-94, N=1~cDNA EST yk255f8.5 comes from this gene~cDNA EST yk255f8.3 comes from this gene~cDNA EST yk561c5.3 comes from this gene~c> Length = 442 Score = 131 bits (327), Expect = 1e-29 Identities = 107/344 (31%), Positives = 165/344 (47%), Gaps = 31/344 (9%) Query: 21 LPLGTEEVKLS-EALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKV 79 +P E +++ ALGR+VAE++ S D+PP +T DGYAV A D K+ Sbjct: 30 IPRIVESIQVDWSALGRVVAEEVKSSEDMPPVAASTKDGYAVIAHDGIGLK-------KM 82 Query: 80 VGEIHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGD-------EIIIYKP 132 VG AG + ++ G+ V ISTG ++P+ ADAVI E E V EII + Sbjct: 83 VGVSLAGNIYQGAVEIGKCVRISTGGIIPEGADAVIMREYTELVRQDQQSEETEIICKQA 142 Query: 133 AYPGLGVMKKGVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEI 192 G + G D+ ++V ++G + +L+A G+ ++V++KP V +ISTG+E+ Sbjct: 143 VQVGENIRLPGSDVRSSDVIVPFEAQIGSAEFGILNAFGIRTIKVYKKPVVTVISTGSEV 202 Query: 193 -------VLPGSELKP-GQIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGV 244 V P E P G + D N L E G I G DD+E L + + E + Sbjct: 203 GVIFLVLVSPMVENVPLGMVRDSNAPQLVALFKEHGFNVIDGGRVVDDKEGLDKKLTECL 262 Query: 245 RVADIVVISGGASGGMRDLTASVIEELG-EVKVHGIAIQPGKPTII------GEINGKPV 297 +D++V +GG S G +D + + LG +++ ++++PG P + E K V Sbjct: 263 EHSDVIVTTGGVSMGEQDYMKNALLHLGFKIEFGRVSMKPGLPCTVATRESASERKLKVV 322 Query: 298 FGLPGYPTSCLTNFTLLVVPLLLRALG-REGKVRKVKARLKHKI 340 LPG P S L VPL+ G R K+ R+ I Sbjct: 323 LALPGNPASAWVCSHLFAVPLIRDMSGYRRINHTKINVRIAQDI 366 >pir||H72739 probable molybdopterin biosynthesis moeA protein APE0450 - Aeropyrum pernix (strain K1) >gi|5104096|dbj|BAA79412.1| (AP000059) 577aa long hypothetical molybdopterin biosynthesis moeA protein [Aeropyrum pernix] Length = 577 Score = 126 bits (313), Expect = 5e-28 Identities = 117/387 (30%), Positives = 190/387 (48%), Gaps = 24/387 (6%) Query: 26 EEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIHA 85 E + L A+GR +A + PP+ R +DG AV + S L+V + Sbjct: 40 ESLGLPAAIGRPLARKAVARGCYPPYPRVNLDGCAVDSSRVSRGSV-----LRVTARLRP 94 Query: 86 GEEP-KLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAYPG--LGVMKK 142 G EP +L ++G V++ TGA LP ADAV+ E+++ +G+ ++ + A P +GV Sbjct: 95 GMEPVELVDREGGCVWVDTGAPLPVGADAVVPLEELDMLGEGVVRLE-AEPRRWMGVADP 153 Query: 143 GVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELKPG 202 D G +++ +GE + + A L++ GV V + + + S G+E+ + G Sbjct: 154 CSDAMDGSVVLGEGEVVTPEAVASLASAGVHDVEAGSRLRACVASVGDELRSLEECREGG 213 Query: 203 QIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVA-DIVVISGGASGGMR 261 + + N + E + LGI D E+L L I+V SGG+S G+ Sbjct: 214 GVCETNRLLARSRLEAAEVEVVDLGIHPDRPETLSSLAAAARGSGCHILVTSGGSSVGLS 273 Query: 262 DLTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPGYPTSCLTNFTLLVVPLLLR 321 D + E+ + V G+AI+PG+PT + ++G PV+ LPG P S + L ++P L Sbjct: 274 DYALAGPED---IVVRGLAIRPGRPTTLSIVDGIPVYSLPGNPRSAGSAIDLFLLPSLAA 330 Query: 322 A-LGREGKVRKVKARLKHKIFSVK-GRR-QFLPVKLE--GG--VAVPILKGSGAVTSFID 374 A L V ++A L + VK GRR ++PV GG AVP+ S S+ Sbjct: 331 AGLPVATVVPGMRAVL---LAGVKPGRRLSYIPVAAVYCGGRLYAVPVSTESYMTVSWAA 387 Query: 375 ADGFIEIPETVESVDEGEEVEVTLFEG 401 ADG+I + E ++++ GEE VT+ G Sbjct: 388 ADGYIAV-EPGKALEPGEEASVTIVRG 413 >pir||F72773 probable molybdopterin biosynthesis protein APE0177 - Aeropyrum pernix (strain K1) >gi|5103567|dbj|BAA79088.1| (AP000058) 386aa long hypothetical molybdopterin biosynthesis protein [Aeropyrum pernix] Length = 386 Score = 100 bits (247), Expect = 3e-20 Identities = 81/280 (28%), Positives = 133/280 (46%), Gaps = 16/280 (5%) Query: 23 LGTEEVKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGE 82 L TE + S+++GRI+AED+ SP D P A +DGYAV D+ A ++LK G Sbjct: 25 LHTEIIPSSQSVGRILAEDLESPNDTPEEPLAAMDGYAV---DSTSAKPGARLRLKDRGP 81 Query: 83 IHAGEEPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDEIIIYKPAYPGLGVMKK 142 + +GE V + TG LP ADAV++ E I + V + Sbjct: 82 VASGE----------AVPVDTGDPLPPGADAVVRREAARVEDGYIYVSAGVSKWENVFRP 131 Query: 143 GVDISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELKPG 202 G +++G L +G+ + AL+ GV+ V+V+R + ++ G+E++ P + G Sbjct: 132 GEFVARGSRLASRGDVISPYLAALIMQAGVKSVKVYRIKSI-VMPVGSELLHPETMTGDG 190 Query: 203 QIYDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISGGASGGMRD 262 + D G ++ + E + D RE L+E I + ADI+V GG+S G RD Sbjct: 191 SL-DYIGPMVTGLLRGWS-EPRLVPPVPDGREELEEAINRALDEADILVTIGGSSVGRRD 248 Query: 263 LTASVIEELGEVKVHGIAIQPGKPTIIGEINGKPVFGLPG 302 +++ +G++ V G K + + + V LPG Sbjct: 249 SLKALVASMGQLVVPGFGASVVKRGGLAVVRNRIVTMLPG 288 >pir||T36508 probable molybdenum cofactor biosynthesis protein - Streptomyces coelicolor >gi|5457262|emb|CAB46950.1| (AL096822) putative molybdenum cofactor biosynthesis protein [Streptomyces coelicolor A3(2)] Length = 465 Score = 97.9 bits (240), Expect = 2e-19 Identities = 94/375 (25%), Positives = 157/375 (41%), Gaps = 23/375 (6%) Query: 28 VKLSEALGRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIHAGE 87 V L ALG +A + + D+P FD + +DG+AV + + + AG Sbjct: 93 VPLDAALGLTLAAPLAALTDLPSFDTSAMDGWAVAGPGPWAVRDEG---------VLAGH 143 Query: 88 EPKLELKKGETVYISTGAMLPKNADAVIQFEDVERVGDE---IIIYKPAYPGLGVMKKGV 144 L GE V I+TGA +P + AV++ E DE + + G + +G Sbjct: 144 AAPAPLIDGEAVRIATGARIPPDTTAVLRTEHGR--SDERGRLHPTREVVHGQDIRPRGQ 201 Query: 145 DISKGRLLVRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELKPGQI 204 + G L+ G L +A G + + +P+V ++ G+E++ G G I Sbjct: 202 ECRSGDQLLPVGTLATPAVLGLAAAAGYDTLTAVPRPRVDVLVLGDELLTQGLP-HDGLI 260 Query: 205 YDINGRALSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISGGASGGMRDLT 264 D G L + LG E + DD ++L + AD++V +GG + G D Sbjct: 261 RDALGPMLPPWLRALGAEVRTVRRIGDDAKALHRAVT--TSEADLIVTTGGTAAGPVDHV 318 Query: 265 ASVIEELG-EVKVHGIAIQPGKPTIIGEI-NGKPVFGLPGYPTSCLTNFTLLVVPLLLRA 322 + +G E+ V G+ +PG P ++ + + + + GLPG P + ++ L P LLR Sbjct: 319 HPTLRRIGAELLVDGVKARPGHPMLLARLKDDQHLVGLPGNPLAAVSGLLTLAEP-LLRT 377 Query: 323 LGREGKVRKVKARLKHKIFSVKGRRQFLPVKLEGGVAVPI-LKGSGAVTSFIDADGFIEI 381 L L+ + + +PV L G AVP+ G + AD + Sbjct: 378 LAARPAPEPYTLPLRDAVHGHPHDTRLVPVVLRGEGAVPLRYNGPAMLRGIAAADALAVV 437 Query: 382 PETVESVDEGEEVEV 396 P G+E E+ Sbjct: 438 PP--GGARSGQEAEL 450 >pir||T42407 gephyrin homolog - Caenorhabditis elegans >gi|2811220|gb|AAB97841.1| (AF042069) LIN-46 [Caenorhabditis elegans] >gi|2811222|gb|AAB97842.1| (AF042070) LIN-46 [Caenorhabditis elegans] Length = 391 Score = 93.2 bits (228), Expect = 5e-18 Identities = 89/333 (26%), Positives = 144/333 (42%), Gaps = 36/333 (10%) Query: 35 GRIVAEDIYSPIDIPPFDRATVDGYAVRAEDTFMASEANPIKLKVVGEIHAGEEPKLELK 94 GRI+AEDI + DIP + VDG+A+ K ++VG A EL Sbjct: 41 GRILAEDIITEYDIPAQRTSIVDGFAIIVNQL-------GTKREIVGLSTAVTPYNAELI 93 Query: 95 KGETVYISTGAMLPKNADAVIQFEDVERVGDE--IIIYKPAYPGLGVMKKGVDISKGRLL 152 E V I+ G ++P AD V+ E+V + +E I + + G + + G + G +L Sbjct: 94 SNECVRITIGGVVPDGADTVVPIENVALLKEEKCIEVLRKPKEGDNIREVGSEAKTGEIL 153 Query: 153 VRKGERLGFKQTALLSAVGVERVRVFRKPKVAIISTGNEIVLPGSELKPGQIY-DINGRA 211 ++ G L LL A+G+ +V +++KP+V ++S GS+L ++Y N Sbjct: 154 LKDGHHLDTMSITLLHALGISQVEIYKKPRVCVLSI-------GSDLNSNKMYGSFNRSQ 206 Query: 212 LSDAVNELGGEGIFLGIARDDRESLKELIEEGVRVADIVVISGGASGGMRDLTASVIEEL 271 L + G I G + + ++E I A ++V GG A VI E+ Sbjct: 207 LLELFQSQGFTAIDAGSSTEHITEVEEKIRTAASFACVLVTVGG---------AQVIREV 257 Query: 272 GEV-----KVHGIAIQPGKPTI-IGEINGKPVF--GLPGYPTSCLTNFTLLVVPLLLRAL 323 + ++ + PG T+ G+I+ PV P Y S L V P+L Sbjct: 258 AKTLKFKFEIQDVDSTPGNFTVSTGKIDETPVVLSIFPEYHVSSWIGANLFVSPILRAME 317 Query: 324 GREGKV-RKVKARLKHKIFSVKGRRQFLPVKLE 355 G+ + + KA L I S +FL + E Sbjct: 318 GQNSETSHRFKAELTQPI-SKTSETRFLRARSE 349 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.317 0.141 0.392 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 148003449 Number of Sequences: 2977 Number of extensions: 6590256 Number of successful extensions: 18794 Number of sequences better than 1.0e-10: 63 Number of HSP's better than 0.0 without gapping: 45 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 18562 Number of HSP's gapped (non-prelim): 69 length of query: 402 length of database: 189,106,746 effective HSP length: 57 effective length of query: 345 effective length of database: 154,992,987 effective search space: 53472580515 effective search space used: 53472580515 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.6 bits) S2: 166 (69.1 bits)