BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1438 (PAB1438) DE:DNA DAMAGE-INDUCIBLE PROTEIN.
         (449 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||C75053 DNA damage-inducible protein. PAB1438 - Pyrococcus a...   884  0.0
pir||E71172 probable damage-inducible protein - Pyrococcus horik...   791  0.0
pir||B75053 dinf related PAB1439 - Pyrococcus abyssi (strain Ors...   526  e-148
pir||C71172 hypothetical protein PH0575 - Pyrococcus horikoshii ...   511  e-144
gb|AAG19206.1| (AE005017) Vng0727c [Halobacterium sp. NRC-1]          249  5e-65
pir||E72471 probable DNA-damage-inducible protein APE2414 - Aero...   234  1e-60
pir||H70158 conserved hypothetical integral membrane protein BB0...   204  2e-51
dbj|BAB04605.1| (AP001510) unknown conserved protein [Bacillus h...   201  2e-50
sp|P54181|YPNP_BACSU HYPOTHETICAL 48.5 KD PROTEIN IN ILVA 3'REGI...   184  1e-45
pir||G72220 conserved hypothetical protein - Thermotoga maritima...   170  3e-41
dbj|BAB05882.1| (AP001514) unknown conserved protein in others [...   165  1e-39
gi|11499066 conserved hypothetical protein [Archaeoglobus fulgid...   164  1e-39
pir||H72331 conserved hypothetical protein - Thermotoga maritima...   162  5e-39
pir||A82049 conserved hypothetical protein VC2671 [imported] - V...   155  1e-36
pir||A75151 damage-inducible protein PAB0243 - Pyrococcus abyssi...   151  1e-35
sp|Q58119|Y709_METJA HYPOTHETICAL PROTEIN MJ0709 >gi|2128027|pir...   148  2e-34
pir||G71191 probable DNA damage-inducible protein - Pyrococcus h...   147  2e-34
pir||C69140 conserved hypothetical protein MTH314 - Methanobacte...   145  1e-33
pir||A69905 conserved hypothetical protein yoeA - Bacillus subti...   139  5e-32
gb|AAG20342.1| (AE005107) DNA damage-inducible protein; DinF [Ha...   136  4e-31
pir||E70312 conserved hypothetical protein aq_128 - Aquifex aeol...   135  1e-30
dbj|BAB06655.1| (AP001517) unknown conserved protein [Bacillus h...   132  1e-29
emb|CAA84073.1| (Z34303) DinF protein [Streptococcus pneumoniae]      131  2e-29
pir||JC4561 DNA damage-inducible protein homolog - Pyrococcus sp...   125  1e-27
pir||G82392 conserved hypothetical protein VCA0989 [imported] - ...   122  7e-27
pir||H69837 conserved hypothetical protein yisQ - Bacillus subti...   122  1e-26
sp|P45272|YDHE_HAEIN HYPOTHETICAL PROTEIN HI1612 >gi|1074865|pir...   119  7e-26
pir||H71898 hypothetical protein jhp0696 - Helicobacter pylori (...   111  2e-23
pir||E82296 conserved hypothetical protein VC0650 [imported] - V...   110  3e-23
pir||G64614 conserved hypothetical integral membrane protein HP0...   106  6e-22
gb|AAG10466.1|AF279106_28 (AF279106) predicted cation efflux pum...   102  6e-21
pir||A71849 hypothetical protein jhp1110 - Helicobacter pylori (...   101  1e-20
gb|AAG20494.1| (AE005121) DNA damage-inducible protein; Dip1 [Ha...   100  4e-20
pir||C72561 hypothetical protein APE1773 - Aeropyrum pernix (str...    99  9e-20
pir||H64667 conserved hypothetical integral membrane protein HP1...    98  2e-19
pir||H81402 probable integral membrane protein Cj0560 [imported]...    98  3e-19
pir||H82186 probable multidrug resistance protein NorM VC1540 [i...    97  4e-19
dbj|BAA15804.1| (D90837) ORF_ID:o347#5~similar to [SwissProt Acc...    96  6e-19
sp|P76352|YEEO_ECOLI HYPOTHETICAL 60.1 KDA PROTEIN IN AMN-CBL IN...    96  6e-19
pir||T36597 hypothetical protein SCH24.32c - Streptomyces coelic...    96  6e-19
dbj|BAA31456.1| (AB010463) NorM [Vibrio parahaemolyticus]              94  2e-18
pir||B83476 probable transporter PA1361 [imported] - Pseudomonas...    92  1e-17
pir||F69906 conserved hypothetical protein yojI - Bacillus subti...    89  8e-17
pir||G70172 conserved hypothetical integral membrane protein BB0...    88  2e-16
dbj|BAB07764.1| (AP001520) unknown conserved protein in others [...    87  5e-16
dbj|BAB04579.1| (AP001510) unknown conserved protein [Bacillus h...    86  9e-16
gb|AAG19201.1| (AE005016) DNA damage-inducible protein; Dip2 [Ha...    84  3e-15
gb|AAF21214.1|AC013483_38 (AC013483) putative integral membrane ...    83  8e-15
gi|8922709 hypothetical protein FLJ10847 [Homo sapiens] >gi|7023...    81  3e-14
pir||E82175 conserved hypothetical protein VC1631 [imported] - V...    80  4e-14
sp|Q55364|Y896_SYNY3 HYPOTHETICAL 49.7 KDA PROTEIN SLR0896 >gi|7...    79  1e-13
pir||H75559 conserved hypothetical protein - Deinococcus radiodu...    75  1e-12
pir||E82527 multidrug efflux protein XF2686 [imported] - Xylella...    75  1e-12
pir||D81950 probable transmembrane efflux protein NMA1022 [impor...    75  2e-12
gb|AAG27731.1|AF312031_1 (AF312031) multi-drug efflux transporte...    75  2e-12
pir||F70172 conserved hypothetical integral membrane protein BB0...    75  2e-12
pir||C81156 conserved hypothetical protein NMB0812 [imported] - ...    75  2e-12
pir||T02512 hypothetical protein T19C21.18 - Arabidopsis thalian...    74  4e-12
pir||A82984 hypothetical protein PA5294 [imported] - Pseudomonas...    74  4e-12
pir||T50435 conserved hypothetical protein SPCC4B3.13 [imported]...    73  5e-12
pir||G82364 DNA-damage-inducible protein F VC0090 [imported] - V...    71  2e-11
pir||T08969 hypothetical protein F19B15.170 - Arabidopsis thalia...    71  3e-11
sp|P37340|YDHE_ECOLI HYPOTHETICAL 49.4 KDA PROTEIN IN RIBC-PYKF ...    70  4e-11
gi|11428103 hypothetical protein FLJ10847 [Homo sapiens]               69  1e-10

>pir||C75053 DNA damage-inducible protein. PAB1438 - Pyrococcus abyssi  (strain
           Orsay) >gi|5458833|emb|CAB50320.1| (AJ248287) DNA
           DAMAGE-INDUCIBLE PROTEIN. [Pyrococcus abyssi]
           Length = 449
           
 Score =  884 bits (2260), Expect = 0.0
 Identities = 449/449 (100%), Positives = 449/449 (100%)

Query: 1   MANIERTREEILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVW 60
           MANIERTREEILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVW
Sbjct: 1   MANIERTREEILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVW 60

Query: 61  PLLWFMMSLGSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISP 120
           PLLWFMMSLGSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISP
Sbjct: 61  PLLWFMMSLGSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISP 120

Query: 121 FALRFIKVTPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILN 180
           FALRFIKVTPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILN
Sbjct: 121 FALRFIKVTPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILN 180

Query: 181 IILDPVFIFILDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIK 240
           IILDPVFIFILDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIK
Sbjct: 181 IILDPVFIFILDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIK 240

Query: 241 TFKIGLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGT 300
           TFKIGLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGT
Sbjct: 241 TFKIGLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGT 300

Query: 301 MVGQNIGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKV 360
           MVGQNIGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKV
Sbjct: 301 MVGQNIGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKV 360

Query: 361 VKYFAASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLGDSAGVW 420
           VKYFAASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLGDSAGVW
Sbjct: 361 VKYFAASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLGDSAGVW 420

Query: 421 IGMGLSNVISALIGFAWFLKGSWMRRIVE 449
           IGMGLSNVISALIGFAWFLKGSWMRRIVE
Sbjct: 421 IGMGLSNVISALIGFAWFLKGSWMRRIVE 449


>pir||E71172 probable damage-inducible protein - Pyrococcus horikoshii
           >gi|3256983|dbj|BAA29666.1| (AP000002) 449aa long
           hypothetical damage-inducible protein [Pyrococcus
           horikoshii]
           Length = 449
           
 Score =  791 bits (2021), Expect = 0.0
 Identities = 385/449 (85%), Positives = 423/449 (93%)

Query: 1   MANIERTREEILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVW 60
           MANIE+ REEILSGSIEKTL+RLAYPLIINNLVQVMYNLTDTFWLAKLGR+ELSAPGTVW
Sbjct: 1   MANIEKAREEILSGSIEKTLIRLAYPLIINNLVQVMYNLTDTFWLAKLGRAELSAPGTVW 60

Query: 61  PLLWFMMSLGSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISP 120
           PLLWFM+S+GSGF VAGFAMVSQY+GAGEYKKAS+VAGSLYSLLL LS ++A +GI+ISP
Sbjct: 61  PLLWFMISIGSGFAVAGFAMVSQYVGAGEYKKASKVAGSLYSLLLALSTIIAFLGILISP 120

Query: 121 FALRFIKVTPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILN 180
            AL+FIKVTPDVYPYALKYM  +F G+P+ALTL+ FNF+LRA GDTKTPVKVNILTI+LN
Sbjct: 121 LALKFIKVTPDVYPYALKYMKIVFGGIPIALTLYAFNFILRAVGDTKTPVKVNILTILLN 180

Query: 181 IILDPVFIFILDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIK 240
           IILDPVFIF L+ GVLGAA+AT+ISEG GS+IGGYLLFTG+V IK+S +DL PD+ LYIK
Sbjct: 181 IILDPVFIFGLNYGVLGAALATVISEGTGSVIGGYLLFTGRVSIKLSLEDLSPDIKLYIK 240

Query: 241 TFKIGLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGT 300
           TFKIGLPASI +STNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGT
Sbjct: 241 TFKIGLPASISESTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGT 300

Query: 301 MVGQNIGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKV 360
           MVGQN+GAE Y+RA+E+AIKAM TNFLIL+FGT+LF+ FREEIFRFFINDPGI+KESEKV
Sbjct: 301 MVGQNVGAEKYERAKEIAIKAMLTNFLILIFGTMLFIIFREEIFRFFINDPGILKESEKV 360

Query: 361 VKYFAASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLGDSAGVW 420
           VKYFAASFPFFGIFSAVTNVFASAGHTKKNL LG+IRLWGLRIPLSYYLG TL DSAGVW
Sbjct: 361 VKYFAASFPFFGIFSAVTNVFASAGHTKKNLTLGLIRLWGLRIPLSYYLGKTLKDSAGVW 420

Query: 421 IGMGLSNVISALIGFAWFLKGSWMRRIVE 449
           IGMGLSNVI+AL+GF WFLKGSWMRRIVE
Sbjct: 421 IGMGLSNVIAALVGFLWFLKGSWMRRIVE 449


>pir||B75053 dinf related PAB1439 - Pyrococcus abyssi (strain Orsay)
           >gi|5458832|emb|CAB50319.1| (AJ248287) dinF related
           [Pyrococcus abyssi]
           Length = 468
           
 Score =  526 bits (1341), Expect = e-148
 Identities = 258/466 (55%), Positives = 339/466 (72%), Gaps = 17/466 (3%)

Query: 1   MANIERTREEILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVW 60
           M  ++  R EIL G IEKTLL+LA+P+++NNL+QV+YN+TDTFWL KLGR  LSAPG  W
Sbjct: 3   MEKVKAMRREILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAW 62

Query: 61  PLLWFMMSLGSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISP 120
           P++  +M+LG GF +AGF++V QYIGAG++KKA+R AG+L+SL+L  S L A I I+I P
Sbjct: 63  PIIGTLMALGMGFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILP 122

Query: 121 FALRFIKVTPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILN 180
            AL F+ VTP + PYA +Y I IFAGVPV+     FN ++RA GDTKTPVK++ LT+ LN
Sbjct: 123 LALDFMNVTPSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLN 182

Query: 181 IILDPVFIFILDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIK 240
           IILDP+FIFI  +GVLGAA+AT++S  +G+IIG  +L +GK G+KI+ +DL+PD   Y K
Sbjct: 183 IILDPIFIFIFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSK 242

Query: 241 TFKIGLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGT 300
             ++GLP+SIG S NSFGFV+L RII  +G V +A Y IT RL NF+ + + GIS AMGT
Sbjct: 243 IVRVGLPSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGT 302

Query: 301 MVGQNIGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKV 360
           MV QN+GAE Y+RA+ +A + M  NF I  F  L+   FR  IF+ F++DP +I ES+ V
Sbjct: 303 MVAQNVGAEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIV 362

Query: 361 VKYFAASFPFF-GIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLG-----TTLG 414
           ++YF  S PFF GIF  VT VF+SAGHT K++++ ++RLWG RIPLSY  G     T LG
Sbjct: 363 LEYFLISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLG 422

Query: 415 -----------DSAGVWIGMGLSNVISALIGFAWFLKGSWMRRIVE 449
                       S GV+ GMGLSN ++A+IG AWFLKGSWMRRI++
Sbjct: 423 IRIPMAELFNFTSRGVFFGMGLSNFLAAIIGLAWFLKGSWMRRIID 468


>pir||C71172 hypothetical protein PH0575 - Pyrococcus horikoshii
           >gi|3256981|dbj|BAA29664.1| (AP000002) 472aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 472
           
 Score =  511 bits (1302), Expect = e-144
 Identities = 247/450 (54%), Positives = 334/450 (73%), Gaps = 8/450 (1%)

Query: 8   REEILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMM 67
           R+EIL G IE TL +LA+P+IINNL+QV+YN+TDTFWL KLGR+ LSAPG  WP++  +M
Sbjct: 23  RKEILEGPIEGTLFKLAWPIIINNLIQVLYNITDTFWLGKLGRAALSAPGVSWPIIGTLM 82

Query: 68  SLGSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIK 127
           +LG GF +AGF++V QYIGAG ++KA+R AG+L+SL++  S   A + I+I P+AL F+ 
Sbjct: 83  ALGIGFTMAGFSIVGQYIGAGNFEKANRSAGALFSLIIFFSTASAILSILILPYALSFMH 142

Query: 128 VTPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVF 187
           VT  + PYA KY + IFAGVP++    TFN ++RA GDT+TPVK++++T+ LNIILDP+F
Sbjct: 143 VTSSIRPYAYKYSLIIFAGVPMSFLFMTFNVLMRAIGDTRTPVKISLITVFLNIILDPIF 202

Query: 188 IFILDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIKTFKIGLP 247
           IFIL++GV GAA+AT++S  +G++IG  +L +G+ G+KISR++L+PD   Y K  +IGLP
Sbjct: 203 IFILNLGVEGAALATVLSNSVGTVIGVRILTSGRAGLKISRENLKPDWKFYSKIVRIGLP 262

Query: 248 ASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIG 307
           +SIG S NSFGFV+L RII  +G V +A Y IT RL NF+ + + GIS AM TMV QNIG
Sbjct: 263 SSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMSTMVAQNIG 322

Query: 308 AENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYFAAS 367
           AENY+RA+ +A + M  NFLI     L+   FR  IF+ F+NDP +I ES+ V++YF  S
Sbjct: 323 AENYERAKVIAERTMVINFLIAGIAVLIIGIFRVPIFKVFLNDPMVIAESKIVLEYFLIS 382

Query: 368 FPFF-GIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLG-------DSAGV 419
            PFF GIF  VT  F+S+GHT K++I+ ++RLWG RIPLSY  G            S GV
Sbjct: 383 VPFFNGIFVVVTGAFSSSGHTVKSMIMSMLRLWGFRIPLSYVFGYVPTFAKLFGFTSRGV 442

Query: 420 WIGMGLSNVISALIGFAWFLKGSWMRRIVE 449
           + GMGLSN ++A++G AWFLKGSWMR+I+E
Sbjct: 443 FFGMGLSNFLAAIVGLAWFLKGSWMRKIIE 472


>gb|AAG19206.1| (AE005017) Vng0727c [Halobacterium sp. NRC-1]
           Length = 494
           
 Score =  249 bits (629), Expect = 5e-65
 Identities = 153/454 (33%), Positives = 234/454 (50%), Gaps = 21/454 (4%)

Query: 10  EILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSL 69
           ++ SG I K L  LA P++I NL Q  YNL DTFWL +     L+A    +P+++ ++SL
Sbjct: 18  DLTSGRIGKPLFFLAMPIVITNLFQTAYNLADTFWLGQYNTDALAAISFAFPMVFLLISL 77

Query: 70  GSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVT 129
           G G  VAG  +V+QY GAG+ ++A   A    +  ++ SLLL GIG       L  +  +
Sbjct: 78  GMGISVAGSVLVAQYTGAGKDEQAEYAASQTVTFSVLASLLLGGIGYFFVEDFLSVVGAS 137

Query: 130 PDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIF 189
             V   A  YM  +  G+        F  ++R  GDT TP+ V   +++LNI+LDP  IF
Sbjct: 138 DAVLRPATSYMQVVALGLAAMFGFAVFIALMRGYGDTITPMLVMFGSVVLNIVLDPFLIF 197

Query: 190 ---------------ILDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPD 234
                             +G+ GAAIAT+ S  +   +G  ++F G  G++I+  D+ PD
Sbjct: 198 GWTVVENAPLVGTVSFPRLGIQGAAIATVFSRALAFAVGLAIMFRGTRGVEINAADMLPD 257

Query: 235 VNLYIKTFKIGLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGI 294
           ++   +  +IGLPASI  +  +    LL  I+ T+     A Y I  R+ + +F  A  I
Sbjct: 258 LSYLRRLVRIGLPASIEGTGRALSMNLLLFIVATFPDHIVAAYGIGTRVFSVVFLPAIAI 317

Query: 295 SQAMGTMVGQNIGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFI-----N 349
           ++ + TM GQN+GA    RA   A  A    F +L    L+   + E I   F+     N
Sbjct: 318 ARGVETMTGQNVGAGKPDRAARAARLAATMLFGVLSVLGLIVYWYPEPIVSVFVGAGQEN 377

Query: 350 DPGIIKESEKVVKYFAASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYL 409
              +I+   + ++Y A +F F GI  A T  F  AG T     + +I L  +R PL++  
Sbjct: 378 SAQVIEAGSQFLRYVALTFGFIGIARAYTGSFRGAGKTMVAAAISVITLGVIRFPLAWAT 437

Query: 410 GTTLGDSAGVWIGMGLSNVISALIGFAWFLKGSW 443
             +LG SAG+W+   +SNVI A+I +AW+ +G+W
Sbjct: 438 IGSLG-SAGIWLSFAVSNVIGAIIAYAWYRRGTW 470


>pir||E72471 probable DNA-damage-inducible protein APE2414 - Aeropyrum pernix
           (strain K1) >gi|5106118|dbj|BAA81429.1| (AP000064) 480aa
           long hypothetical DNA-damage-inducible protein
           [Aeropyrum pernix]
           Length = 480
           
 Score =  234 bits (591), Expect = 1e-60
 Identities = 153/459 (33%), Positives = 225/459 (48%), Gaps = 23/459 (5%)

Query: 4   IERTREEILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLL 63
           ++R R  +  G I K +L LA P++   L+       D  +L ++   +L+AP    PLL
Sbjct: 11  LDRKRTWVTQGPIVKVILALATPIVAARLLAATQESVDAIFLGRVSTEDLAAPAAASPLL 70

Query: 64  WFMMSLGSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLS-------LLLAGIGI 116
           W    LG G      A+VSQ IGA +Y  A R A  L    LML        +L A    
Sbjct: 71  WLFAGLGIGINTTLSALVSQAIGARDYASAQRYASKLLGATLMLGAASALAIILTAETVF 130

Query: 117 VISPFALRFIKVTPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILT 176
           ++  F  R ++V       AL Y +    G+P  L L  FN V+ A+GDT+TP KV+ L+
Sbjct: 131 ILQGFQGRSLEV-------ALAYTLVEAVGMPFMLALFYFNAVMAASGDTRTPFKVSALS 183

Query: 177 IILNIILDPVFIFIL----DMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLR 232
            ILN+ILDP+ IF L     +G +GAA+AT+++      I  YLL  G  G ++      
Sbjct: 184 SILNVILDPILIFGLILLPPLGAVGAAVATVLARAAAVSIAFYLLLRGAPGFRVKPS--M 241

Query: 233 PDVNLYIKTFKIGLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFAD 292
           PD  L     +IG P S+     S GF+++  I+   G    A Y ++  + + + +   
Sbjct: 242 PDRQLIGHILRIGGPVSLQRLVVSMGFLVMMGIVARLGAPVVAAYNVSLVIIHIVQSATF 301

Query: 293 GISQAMGTMVGQNIGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPG 352
           G + A  T+VGQN+GA N  RA   A   +A  F +L  G +  +  R  +   F +   
Sbjct: 302 GFNIATATVVGQNLGASNISRAVRAAYTGVALVFGLLSIGAVAIVGGRSMLVSLFTSIEE 361

Query: 353 IIKESEKVVKYFAASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLG-- 410
           +   +E+++   A   PF G F     V   +G T     LGI RLW LRIP +Y L   
Sbjct: 362 VQFYAERMISIVALGMPFLGAFFTAMGVARGSGRTAFISALGIARLWLLRIPAAYTLVYI 421

Query: 411 TTLGDSAGVWIGMGLSNVISALIGFAWFLKGSWMRRIVE 449
            +LGD  GVW+ M LSN+I+  +  AW    +W + IV+
Sbjct: 422 YSLGD-MGVWLAMTLSNIIAGTLAIAWVAGRTWAKPIVK 459


>pir||H70158 conserved hypothetical integral membrane protein BB0473 - Lyme
           disease spirochete >gi|2688416|gb|AAC66867.1| (AE001152)
           conserved hypothetical integral membrane protein
           [Borrelia burgdorferi]
           Length = 454
           
 Score =  204 bits (514), Expect = 2e-51
 Identities = 124/446 (27%), Positives = 220/446 (48%), Gaps = 6/446 (1%)

Query: 6   RTREEILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWF 65
           +TRE IL+G++ K L  +++P++I N++Q  Y+LTD F++ KLG   LSA     P+ +F
Sbjct: 7   KTRELILNGNLYKVLFLISFPIVITNIIQAFYDLTDMFYVGKLGAMPLSALSLAGPVNFF 66

Query: 66  MMSLGSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRF 125
           ++++  G      +++S+ IG G + + SR AG L  L  +LSL +           L  
Sbjct: 67  IIAIAMGMATGSISLMSKCIGEGNFSRFSRYAGQLIVLNFVLSLFVTICAFFFIDHLLDL 126

Query: 126 IKVTPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDP 185
           + V  ++   +  Y       +P+     +  ++L A G+T   + + +   I+N ILDP
Sbjct: 127 LGVKGELKELSRVYFYVTIFAIPIMFLSISITYILNAQGETILSMTIVLFANIVNFILDP 186

Query: 186 VFIFILDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIKTFKIG 245
           + IF  +MG+ GAA AT+ S+ +  +   +L +    G+KI   DL  D+    +   +G
Sbjct: 187 ILIFSFNMGITGAAWATLFSKLLTVVFYLFLTYRLNYGLKIHLKDLVIDIRSIKEIVNLG 246

Query: 246 LPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQN 305
           LP++ G    S  F + N I+        A Y +TN + +F+F  A GI   + ++VGQN
Sbjct: 247 LPSTFGQIMVSLSFFIFNYIVIEISPKFLAAYGLTNTIISFLFLPAMGIGTGIISIVGQN 306

Query: 306 IGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYFA 365
           +GA+   R  EV  K    +  IL+    + +  ++ I R F ND  ++  +   +    
Sbjct: 307 LGAKKVNRVEEVLKKGFFISLAILLIINSIVIFNKQFILRLFTNDLEVLNYANNYLLLTT 366

Query: 366 ASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSY---YLGTTLGDSAGVWIG 422
                +G+          +G TK  +I+  IRLW +R+P+ +   Y G         +I 
Sbjct: 367 IGTFGYGLQQVFFGGLIGSGRTKIAMIVIFIRLWLIRLPVVFIFQYFGIMENSLGYAFI- 425

Query: 423 MGLSNVISALIGFAWFLKGSWMRRIV 448
             +SN ++ +I  A+     W++ I+
Sbjct: 426 --ISNYLAIIILIAFTCTRYWVKPIL 449


>dbj|BAB04605.1| (AP001510) unknown conserved protein [Bacillus halodurans]
           Length = 454
           
 Score =  201 bits (505), Expect = 2e-50
 Identities = 131/441 (29%), Positives = 226/441 (50%), Gaps = 12/441 (2%)

Query: 10  EILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKL-GRSELSAPGTVWPLLWFMMS 68
           +   GSI K ++  ++P+ ++NL+Q  Y +TD+ W+  L G S L A      +++ ++S
Sbjct: 7   DFTEGSITKKMVVFSWPIFLSNLLQTSYQITDSLWVGNLLGASALGALSISATVVFMVLS 66

Query: 69  LGSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKV 128
              G   A   ++SQ  GA +         +   +L +L++LL  IG   +   L+ +  
Sbjct: 67  FIIGLNGATLTVLSQRQGAKDEAGLKASLNAFVFVLGLLAILLGLIGYFSASSILQLLGT 126

Query: 129 TPDVYPYALKYMIAIFAGVPVALTLHTFNF---VLRAAGDTKTPVKVNILTIILNIILDP 185
             ++ P A  Y+   F G+   L L  +NF   VLRA GD+++PV+   + +ILNIILDP
Sbjct: 127 PEEILPLAESYLKINFIGI---LFLFGYNFIGTVLRAMGDSRSPVRFIFIAVILNIILDP 183

Query: 186 VFIFILDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIKTFKIG 245
           + I   ++G+ GAA ATI+S+G  + I G +    K G+      + P+   +   FK+G
Sbjct: 184 LMIAGFNLGIDGAAYATIVSQGT-AFIYGLIYSVRKAGVPFQIPYV-PEKRYFFVLFKLG 241

Query: 246 LPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQN 305
           LPA +   T S G   +  ++ ++G  A A +    RL + +   A  +  A+ T+ GQN
Sbjct: 242 LPAGLSMITISAGVTAILSVVTSFGEEAVAGFGAAQRLDSLIMLPALTLGSAVNTIAGQN 301

Query: 306 IGAENYKRAREVAIK-AMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYF 364
           IGA  ++R R  A +  M    + L+ G + F+   +   R F+ D   +      ++  
Sbjct: 302 IGANKWERVRATAKQGVMLIIAVTLIIGLITFIG-AQFFIRLFVRDEATVAFGAMYIQTI 360

Query: 365 AASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLGDSAGVWIGMG 424
           A  +PF GI   +  +  ++G     L+L II  W LR PL+Y++    G+  G+ +GMG
Sbjct: 361 AFFYPFLGINFVLNGIVRASGAMFPVLLLNIISFWILRYPLTYWMSDLFGE-RGIALGMG 419

Query: 425 LSNVISALIGFAWFLKGSWMR 445
            + V+S+LI   ++  G+W +
Sbjct: 420 FAFVVSSLIATGYYFLGNWRK 440


>sp|P54181|YPNP_BACSU HYPOTHETICAL 48.5 KD PROTEIN IN ILVA 3'REGION
           >gi|7474682|pir||D69939 conserved hypothetical protein
           ypnP - Bacillus subtilis >gi|1256651|gb|AAA96645.1|
           (L77246) 21% identity with the NADH-dehydrogenase
           (ubiquinone) of Caenorhabditis elegans; putative
           [Bacillus subtilis] >gi|2634591|emb|CAB14089.1| (Z99115)
           similar to hypothetical proteins [Bacillus subtilis]
           Length = 445
           
 Score =  184 bits (463), Expect = 1e-45
 Identities = 119/437 (27%), Positives = 211/437 (48%), Gaps = 8/437 (1%)

Query: 10  EILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKL-GRSELSAPGTVWPLLWFMMS 68
           +   G++ K L+  + P+++ N +QV +   D+ W+  L G   L A      ++  ++S
Sbjct: 5   DFTQGNVLKQLVLFSMPIMLGNALQVSFQFIDSLWIGNLLGAKALGAAAVSSTIVLTVLS 64

Query: 69  LGSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKV 128
              G   A   ++SQ  G  + K  +    +   LL  LS+     G  +S   LR +K 
Sbjct: 65  FILGLNNATLTILSQQKGKDDIKGMASYINAFVVLLTGLSIGFGAAGFFLSELLLRLLKT 124

Query: 129 TPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFI 188
              + P A  Y+   F G+      +  + VLRA GD+KTP++     ++LN +L P+FI
Sbjct: 125 PESMIPLAETYLQIQFIGILFLFGYNFISTVLRALGDSKTPLRFIAFAVVLNTVLAPLFI 184

Query: 189 FILDMGVLGAAIATIISEGIGSIIGGYLLFTGK-VGIKISRDDLRPDVNLYIKTFKIGLP 247
            +  MG+ GAA +TI+S+GI  + G + +   K V   I R    P         K+G+P
Sbjct: 185 SVFRMGIAGAAYSTILSQGIAFLYGLFYVIKHKLVPFSIPR---MPKWEESALILKLGIP 241

Query: 248 ASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIG 307
           A +     + G + +  ++ +YG    + +    RL + +   A     A+ +M GQNIG
Sbjct: 242 AGLQMMVITGGMMAIMSVVNSYGDHVVSGFGAVQRLDSIITLPAMAAGTAVNSMAGQNIG 301

Query: 308 AENYKRAREVA-IKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYFAA 366
             N KR   +A +  +A    +LV   ++++ F + + R FI++P  +   E+ +K+ A 
Sbjct: 302 IGNEKRVGTIARLGVIAVISCMLVIAVMIWV-FGKYLIRLFISEPDAVAFGEQYLKWIAF 360

Query: 367 SFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLGDSAGVWIGMGLS 426
            +PF G+   +  +  +AG   + L+L +I  W LR P +      LG   G+ +G+G+S
Sbjct: 361 FYPFIGVNFVLNGIVRAAGAMLQVLVLNLISFWVLRYPFTALFSAWLGQK-GIGLGIGMS 419

Query: 427 NVISALIGFAWFLKGSW 443
            + S+   F ++  G W
Sbjct: 420 FLFSSCAAFLYYRYGRW 436


>pir||G72220 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
           >gi|4982278|gb|AAD36768.1|AE001810_7 (AE001810)
           conserved hypothetical protein [Thermotoga maritima]
           Length = 458
           
 Score =  170 bits (426), Expect = 3e-41
 Identities = 127/439 (28%), Positives = 219/439 (48%), Gaps = 19/439 (4%)

Query: 10  EILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSL 69
           ++L G   K +++L+ P+++  LVQ +YNL D  W+A LG   L+A G  +P+   ++SL
Sbjct: 11  KLLRGDPRKAIVKLSIPMMLAMLVQTIYNLADGIWVAGLGPYALAAIGLFFPVFMVIISL 70

Query: 70  GSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGI-VISPFA---LRF 125
            +G  V   ++VSQ IG  + + A   A    S+ ++LS+++  + I VI PF    L F
Sbjct: 71  AAGIGVGASSVVSQKIGERDKEGADTAA----SVSILLSIVIGFLSIAVILPFISDILIF 126

Query: 126 IKVTPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDP 185
                +    AL+Y + +   +P+ +  +  N V R  GD K  +    +  +LNI LDP
Sbjct: 127 AGAQGETLRLALEYSVILVYFIPLIMFNNVANGVFRGEGDAKRAMVAITIGSLLNIGLDP 186

Query: 186 VFIFILDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIKTFKIG 245
           VFI++  MG+ GAA AT++S  + S++  Y +F  K      R  L+ D  +  +  KIG
Sbjct: 187 VFIYVFGMGIRGAAYATVVSIAVSSLLIAYWMFFKKDTYVSFR--LKWDGEILKRILKIG 244

Query: 246 LPASIGDSTNSFGFVLLNRI-IYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQ 304
           +PAS+   + S    +LN   + + G    A +T   R+ NF      G++ A+ ++ G 
Sbjct: 245 IPASLAQISMSVAIYVLNVFAVRSGGDYGVAVFTSAWRVINFGTVPLIGMAMAVTSVTGA 304

Query: 305 NIGAENYKRAREVAIKAMATNF---LILVFGTLLFMAFREEIFRFFINDPGIIKESEKVV 361
             G  N ++     + A+   F   L ++F  L+F  +   +F +      +  +  K +
Sbjct: 305 AFGERNGEKLETAHLYAVKLGFFVGLAVMFTILIFAPYIARLFTYSQEGEKLYSDLVKAL 364

Query: 362 KYFAASFPF--FGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLG-DSAG 418
           +  +   P   FG+F+  +++F   G   K+LI+ I+R   +++  S+     L     G
Sbjct: 365 RILSLFLPGVPFGMFT--SSMFQGVGQGLKSLIVTIMRTVIMQVVFSWLFVFVLRIGLVG 422

Query: 419 VWIGMGLSNVISALIGFAW 437
           VW G+ L N  SA I F W
Sbjct: 423 VWWGIVLGNTTSAFITFNW 441


>dbj|BAB05882.1| (AP001514) unknown conserved protein in others [Bacillus
           halodurans]
           Length = 464
           
 Score =  165 bits (413), Expect = 1e-39
 Identities = 121/430 (28%), Positives = 214/430 (49%), Gaps = 9/430 (2%)

Query: 9   EEILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLA-KLGRSELSAPGTVWPLLWFMM 67
           E + + +I K L  L+ P +I   V  +YN+ DT +++  +G   ++     +P++  MM
Sbjct: 8   ERLGTEAIPKLLRSLSIPAMIGMFVMALYNVVDTIFISYAVGIEGVAGVTIAFPIMMIMM 67

Query: 68  SLGSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIK 127
           S+     + G +++S+ +G    ++A++V G++ +++L+LS++       +   AL+   
Sbjct: 68  SMAGALGIGGASVISRRLGERRGEEANQVFGNILTVILVLSVIGFISAFTLLGPALQLFG 127

Query: 128 VTPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVF 187
            T     YA  Y+  I  G          N ++R+ G+    +   I+  +LNI+LD +F
Sbjct: 128 ATSVTQGYATDYLFPILLGSIFFFFAFAANNIIRSEGNATFAMVTMIVPAVLNILLDVLF 187

Query: 188 IFILDMGVLGAAIATIISE-GIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIKTFKIGL 246
           IF L+MGVLGA+IAT+I++  +  ++  Y L TGK  + +   DLR   ++  +   +GL
Sbjct: 188 IFGLNMGVLGASIATVIAQASVTGLVLRYFL-TGKSTLSLHWSDLRMKGSVIKEVCLVGL 246

Query: 247 PASIGDSTNSFGFVLLNRIIYTYGTVAF-ATYTITNRLTNFMFAFADGISQAMGTMVGQN 305
           PA +  S+ S   + +N ++  +G+  +   + +  R+  F+     GI QAM  +VG N
Sbjct: 247 PAFVQQSSASLMMIAINSMLLRFGSDFYVGVFGLVQRIMMFVMMPMMGIMQAMQPIVGYN 306

Query: 306 IGAENYKRAREVAIKA--MATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKY 363
            GA+ Y R RE  +    +AT F I +F   L M F E + R F  D  +I+     +  
Sbjct: 307 YGAKQYSRLRETVMLGFKVATIFSIGIFA--LLMLFPEALLRVFTADREVIQAGVSAMHI 364

Query: 364 FAASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLGDSAGVWIGM 423
                   G       ++ S G  K+ LIL + R     IPL   L    G S GVW   
Sbjct: 365 LFCVTFLIGAQIVAGGLYQSLGKPKQALILSLSRQIIFLIPLVLILPHIFGLS-GVWWAF 423

Query: 424 GLSNVISALI 433
            +++V+S ++
Sbjct: 424 PIADVLSFIL 433


>gi|11499066 conserved hypothetical protein [Archaeoglobus fulgidus]
           >gi|7451040|pir||F69433 conserved hypothetical protein
           AF1471 - Archaeoglobus fulgidus
           >gi|2649097|gb|AAB89777.1| (AE001001) conserved
           hypothetical protein [Archaeoglobus fulgidus]
           Length = 447
           
 Score =  164 bits (412), Expect = 1e-39
 Identities = 117/436 (26%), Positives = 211/436 (47%), Gaps = 16/436 (3%)

Query: 10  EILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSL 69
           E+L+G  +K +L+L+ P++++NL+  +YNL D  W+A LG   LSA G  +P+ +  +++
Sbjct: 5   EVLTGDPKKAILKLSAPMVVSNLIFTLYNLVDGIWVAGLGPDALSAVGLFFPIFFVFIAI 64

Query: 70  GSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVT 129
             G  V   + VS+ IGA  Y  A   A    ++ +++S+ +  + +V     + F+   
Sbjct: 65  SFGLSVGANSAVSRRIGAKRYDAACVAATLAVAMGILVSIPMT-LSVVFLNGVMVFLGAD 123

Query: 130 PDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIF 189
            ++   A+ Y   +  G    +  +    +L   G+ +  +  N    +LN++LDP+FI+
Sbjct: 124 GEILRLAVDYGSIMVLGSVFLVFSNVSAGILNGEGNARMAMYANAAGSLLNMVLDPIFIY 183

Query: 190 ILDMGVLGAAIATIISEGIGSIIGGYLLFTGK--VGIKISRDDLRPDVNLYIKTFKIGLP 247
           +L  G+ GAAIA++IS  + SI+  +   +G+  V  +++  +L    +L     ++G+P
Sbjct: 184 LLGYGIAGAAIASVISMALSSIVFSFWFLSGRSYVRFRVAGWNLPTVFDL----LRVGMP 239

Query: 248 ASIGDSTNSFGFVLLNR-IIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNI 306
           AS+   T S  F+L+NR +I T G+   A YT   RL  F F    G+S A+  + G   
Sbjct: 240 ASLSMLTMSVAFMLINRVVIETGGSEGLAAYTSAWRLIQFGFVPLFGVSAALTAVSGAAY 299

Query: 307 GAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVK---- 362
           GA N ++  E     +     +      L +AF  +I   F          E++V+    
Sbjct: 300 GARNPRKIGESLNYTVKLLLAVDAAILALMVAFAPQIALIFTYTEVSAVMYEEIVRTIRI 359

Query: 363 -YFAASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLGDSAGVWI 421
             F   F   G+ S+   VF   G  +++  + ++R    ++ L Y L    G   GV +
Sbjct: 360 AAFVLLFAPLGVSSSA--VFQGMGKGERSFAITVLRAIVFQVSLCYVLAVPFGFD-GVLL 416

Query: 422 GMGLSNVISALIGFAW 437
           G  L   +    GF+W
Sbjct: 417 GFVLGEALGCFTGFSW 432


>pir||H72331 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
           >gi|4981345|gb|AAD35897.1|AE001748_13 (AE001748)
           conserved hypothetical protein [Thermotoga maritima]
           Length = 464
           
 Score =  162 bits (407), Expect = 5e-39
 Identities = 119/439 (27%), Positives = 206/439 (46%), Gaps = 8/439 (1%)

Query: 16  IEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSGFVV 75
           I K L++LA P +  N++Q+++ + DT +L       +S  G    + W +  +     +
Sbjct: 18  IRKELIKLALPAMGENVLQMLFGMADTAFLGHYSWKAMSGVGLSNQVFWVVQVVLIAASM 77

Query: 76  AGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYPY 135
                ++  IGAG  K    +A +   L +   ++L  +  +       F  +  ++   
Sbjct: 78  GATVTIANAIGAGNRKAVRSLAWNSVFLAIFTGVILTALTPLSDVLINIFPNLEGEIESS 137

Query: 136 ALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIF----IL 191
           A +Y+  I +G      +  F+ +LR AGDT+TP+ V  LT  LNI LD   IF      
Sbjct: 138 AKEYLKVILSGSMGFSIMAVFSAMLRGAGDTRTPMIVTGLTNFLNIFLDYAMIFGKFGFP 197

Query: 192 DMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIKTFKIGLPASIG 251
           +MGV GAA+ATI+S  +G+ I  Y++F  +   ++ +  + P  +   +  ++G P +I 
Sbjct: 198 EMGVRGAAVATILSRFVGAGILTYVIFK-REEFQLRKGLVPPKWSSQKEILRVGFPTAIE 256

Query: 252 DSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAENY 311
           +   S G ++   I+   G  A+A + I   + +  F  A GIS A+ T+VG+  G  N 
Sbjct: 257 NFVFSTGVLMFANILLIAGAEAYAGHRIGINVESLSFMPAFGISVAITTLVGRYNGMGNK 316

Query: 312 KRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYFAASFPFF 371
           +    V  +    + L  V   ++   F E + R F +DP II+ S+  VK       F 
Sbjct: 317 EHVLGVIRQGWILSLLFQVTVGIIIFLFPEPLIRIFTSDPQIIEISKLPVKIIGLFQFFL 376

Query: 372 GIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGT--TLGDSAGVWIGMGLSNVI 429
            I S +       G+T   +I+  I +W  R+P+++ +     LG   G WIGM    + 
Sbjct: 377 AIDSTMNGALRGTGNTLPPMIITFISIWTARLPVAFVMVKYFQLG-LLGAWIGMIADIIF 435

Query: 430 SALIGFAWFLKGSWMRRIV 448
            + +   +FL G W +R V
Sbjct: 436 RSTLKLLFFLSGKWEKRAV 454


>pir||A82049 conserved hypothetical protein VC2671 [imported] - Vibrio cholerae
           (group O1 strain N16961) >gi|9657264|gb|AAF95812.1|
           (AE004332) conserved hypothetical protein [Vibrio
           cholerae]
           Length = 460
           
 Score =  155 bits (387), Expect = 1e-36
 Identities = 113/448 (25%), Positives = 222/448 (49%), Gaps = 15/448 (3%)

Query: 1   MANIERTREEILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVW 60
           +A +   +  +LS  I   L ++  P+I   +  +M+NL DTF+++ LG   L+A    +
Sbjct: 9   VAQLMHDKHGLLSAPIPLVLRQMTVPMIFGLVAILMFNLVDTFFISLLGTQALAAISYTF 68

Query: 61  PLLWFMMSLGSGFVVAGFAMVSQYIGAGEYKKASRVA--GSLYSLLLMLSLLLAGIGIVI 118
           P+ + +  +  G  V     + + +G G+ ++A+RV+  G L +LLL+ +    G+ + I
Sbjct: 69  PVTFAVNCITMGIGVGLSTCIGRLLGQGDGRQAARVSSHGLLLALLLVAAASTLGL-LTI 127

Query: 119 SPFALRFIKVTPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTII 178
            P  L  +  + ++ P   +YM+  +  +P+ +     N  +RA GDTKTP K+ +L  +
Sbjct: 128 EPLFL-LLGASHELIPLIKEYMVVWYLTIPLLVLPMAGNSAIRATGDTKTPAKIMMLAGL 186

Query: 179 LNIILDPVFIF----ILDMGVLGAAIATIISEGIGSIIGG-YLLFTGKVGIKI-SRDDLR 232
           +N  LDP+ IF      ++G+ GAAIA+  S  +G++IG  YLL   +  + I S   LR
Sbjct: 187 INGALDPLLIFGYGPFPELGIQGAAIASAFS-WLGALIGSLYLLIKREKLLAIPSLPHLR 245

Query: 233 PDVNLYIKTFKIGLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFAD 292
            D   + +  KIG PA++  + N     LL  ++ ++GT A A Y  T R+ + +     
Sbjct: 246 DD---WQQILKIGTPAALSTAMNPISGALLMIMLSSHGTAAVAAYGATQRIESILILVLM 302

Query: 293 GISQAMGTMVGQNIGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPG 352
            ++ A+   + QN+GA+N  R+      ++  + L  +   ++ +     +   F  +  
Sbjct: 303 SLTSALTPFMAQNLGAQNPARSFAGLFLSLRFSLLFQLMVFIMMVPLSIPLAALFSQEQA 362

Query: 353 IIKESEKVVKYFAASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTT 412
           +       +     S+ F G+   + +   +     K      +RL+   +P + ++G  
Sbjct: 363 VRDLLWHYLLVVPVSYGFQGVVMMLVSALNALHQPLKAFQWSFMRLFVFTLPAA-WIGGR 421

Query: 413 LGDSAGVWIGMGLSNVISALIGFAWFLK 440
           L +  G++IG+ + N++  L+G+ + L+
Sbjct: 422 LYNIEGLFIGIAVGNILGGLLGYLYALR 449


>pir||A75151 damage-inducible protein PAB0243 - Pyrococcus abyssi (strain Orsay)
           >gi|5457798|emb|CAB49288.1| (AJ248284) DAMAGE-INDUCIBLE
           PROTEIN [Pyrococcus abyssi]
           Length = 463
           
 Score =  151 bits (378), Expect = 1e-35
 Identities = 126/461 (27%), Positives = 205/461 (44%), Gaps = 35/461 (7%)

Query: 16  IEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSGFVV 75
           I K L  LA+P I+ N+ Q + NL DT  +  +    L A G    + WFM  +      
Sbjct: 4   IRKKLWTLAWPAIMGNISQTLLNLVDTMIVGHVSSVALGAVGLGGQVSWFMFPIMMAIST 63

Query: 76  AGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYPY 135
              A+V++ +G   +++ASR+A     +  ++ + +   G+ +    L+ +    +V   
Sbjct: 64  GTLALVARRVGEKNFEEASRIAEQSMYIAFIIGIPVMLFGLFLGDEVLKIMGAKGEVLEI 123

Query: 136 ALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIF----IL 191
           A  Y+  +F   P+      F   LR AGDTKTP+K+NIL  ++N +LD + +F      
Sbjct: 124 AYAYLRVLFLFYPIRFMGFAFFSALRGAGDTKTPMKLNILMNVINAVLDYLLVFGKFGFP 183

Query: 192 DMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRD-DLRPDVNLYIKTFKIGLPASI 250
            +G +GAA A+ I   I  ++G YL  T K+ +K   D  LR D+    K  +IG P  +
Sbjct: 184 RLGPVGAAWASGIGITIAFLVGMYLFITNKLILKPVLDLSLRFDI--IEKILRIGTPTML 241

Query: 251 GDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAEN 310
                SF   L   I+  +G +A + + I  R+ +  +  A G S A   +VGQN+GA+ 
Sbjct: 242 ERGLFSFYNFLYVSIVARFGKIALSAHYIGLRIESIAYMPAFGFSIATSALVGQNLGAKK 301

Query: 311 YKRAREVAIKA--MATNFL-ILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYF--- 364
            + A     +A  M T F+  + F  ++F  +  E F    NDP         V Y    
Sbjct: 302 PEEAERTVKEALKMTTMFMSAMAFVLMVFPGYLTEPF-LSHNDPNYQAVKSLAVIYLIIV 360

Query: 365 -AASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLG-------TTLGDS 416
             +  P  G+   ++     AG TK  L +  +     RI  +Y LG        ++G  
Sbjct: 361 GISEIP-LGMTFVLSGALRGAGDTKSPLYVTSVSKLLFRILPAYLLGFGFEIPELSIGPF 419

Query: 417 A------------GVWIGMGLSNVISALIGFAWFLKGSWMR 445
                          WIGM L   ++A + +  F +G W +
Sbjct: 420 TFPGFKFPGMGVIAAWIGMSLETFVTAGLFWLVFKRGKWKK 460


>sp|Q58119|Y709_METJA HYPOTHETICAL PROTEIN MJ0709 >gi|2128027|pir||E64388 conserved
           hypothetical protein homolog MJ0709 - Methanococcus
           jannaschii >gi|1591425|gb|AAB98703.1| (U67517) conserved
           hypothetical protein [Methanococcus jannaschii]
           Length = 450
           
 Score =  148 bits (369), Expect = 2e-34
 Identities = 107/439 (24%), Positives = 213/439 (48%), Gaps = 20/439 (4%)

Query: 10  EILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSL 69
           EIL    +K ++ ++ P+I+   ++ +Y+L D+ W++ LG   L+A G  +P+L  + ++
Sbjct: 5   EILLDDPKKAVIEVSKPIIVATFIESIYSLVDSIWVSGLGADALAAVGASFPILISIYAV 64

Query: 70  GSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFA-----LR 124
             G  +   + +++ +GA   ++A +VA   ++++L L   +AGI  +I+ +        
Sbjct: 65  SWGLSIGISSGIARRVGAKNKEEADKVAN--HAIILAL---IAGILYIIAVYPNLDTLFS 119

Query: 125 FIKVTPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILD 184
            +    D    A+KY   +  G  +         + R  G+TK  +  +++  + NIILD
Sbjct: 120 LMGTYGDCKSLAIKYSSILVLGTVIFTICDALYGIFRGEGNTKIVMIASVIGTLTNIILD 179

Query: 185 PVFIFILDMGVLGAAIATIISEGIGSIIGGYLLFTGK---VGIKISRDDLRPDVNLYIKT 241
           P+FI++L++G+ GA+ AT+I+  I  +I  Y LF  K   V +K+S+   +PD+ +    
Sbjct: 180 PIFIYMLNLGISGASYATLIAIIISLLILAYELFIKKSCYVTVKLSK--FKPDLKIIADL 237

Query: 242 FKIGLPASIGDSTNSFGFVLLNRIIYTYG-TVAFATYTITNRLTNFMFAFADGISQAMGT 300
            ++G+P+++ + T +  F ++  II   G +   A YT   R+T F F    G++    +
Sbjct: 238 IRVGIPSALIEITVAVSFFIMTSIIMMVGDSRGLAVYTGALRITEFGFIPMLGLASGATS 297

Query: 301 MVGQNIGAENYKRAREV---AIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKES 357
           ++G   GA ++++ +      IK      +I+V   +L       +F +     GI +E 
Sbjct: 298 VIGATYGARSFEKLKTAYFYTIKIGVLMEIIIVALIMLLSPILAYLFTYTKTSMGIHEEL 357

Query: 358 EKVVKYFAASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLG-DS 416
            K ++       F       + +F   G  +K+LI+ I R     I  +Y     LG   
Sbjct: 358 VKALRIVPLYLLFTPFILTTSAMFQGIGKGEKSLIISIFRSLICHISYAYLFAVILGLGM 417

Query: 417 AGVWIGMGLSNVISALIGF 435
            G++ G+ +    + +  F
Sbjct: 418 FGIYSGLVVGEFTAGIFAF 436


>pir||G71191 probable DNA damage-inducible protein - Pyrococcus horikoshii
           >gi|3258243|dbj|BAA30926.1| (AP000007) 463aa long
           hypothetical DNA damage-inducible protein [Pyrococcus
           horikoshii]
           Length = 463
           
 Score =  147 bits (368), Expect = 2e-34
 Identities = 124/458 (27%), Positives = 199/458 (43%), Gaps = 33/458 (7%)

Query: 16  IEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSGFVV 75
           + + L  LA+P I+ N+ Q + NL DT  +  +    L A G    + WFM  +      
Sbjct: 4   LRRRLWELAWPAIMGNISQTLLNLVDTMIVGHVSAVALGAVGLGGQVSWFMFPIMMAIST 63

Query: 76  AGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYPY 135
              A+V++ +G G Y++ASR+      +  ++ + +   GI +    LR +    +V   
Sbjct: 64  GTLALVARRVGEGNYREASRITEQSMYIAFLIGIPVMLFGIFLGDEVLRIMGAKGEVLDI 123

Query: 136 ALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIF----IL 191
           A  Y+  +F   P+      F   LR AGDTKTP+K+NIL  ++N ILD + +F      
Sbjct: 124 AYSYLKILFLFYPIRFMGFAFFSALRGAGDTKTPMKLNILMNVINGILDYLLVFGKLGFP 183

Query: 192 DMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIK-ISRDDLRPDVNLYIKTFKIGLPASI 250
            +G +GAA A+ I      ++G YL    K+ +K +    LR   N+  K  +IG P  +
Sbjct: 184 KLGPVGAAWASGIGISSSFLVGLYLFLAHKLILKPVLEFKLR--FNIIEKILRIGTPTML 241

Query: 251 GDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAEN 310
                SF   L   I+  +G +A + + I  R+ +  +  A G S A   +VGQ +GA  
Sbjct: 242 ERGLFSFYNFLYVSIVARFGEIALSAHYIGLRVESIAYMPAFGFSIATSALVGQKLGARK 301

Query: 311 YKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFI--NDPGIIKESEKVVKYF---- 364
              A     +A+      +     + +AF   +   F+  NDP         V Y     
Sbjct: 302 PDEAELTVKEALKMTTAFMSTMAFILVAFPGYLTEPFLSHNDPNYSAVKSLAVIYLIIVG 361

Query: 365 AASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLG-------TTLG--- 414
            +  P  G+   ++     AG TK  L +  +     RI  +Y LG        T+G   
Sbjct: 362 ISEIP-LGMTFVLSGALRGAGDTKSPLYVTSVSKLLFRIIPAYLLGFGFTVPSFTIGSLT 420

Query: 415 ------DSAGV---WIGMGLSNVISALIGFAWFLKGSW 443
                 +  GV   WIGM L   I+A + +  F +G W
Sbjct: 421 FPGFKFEGLGVIAAWIGMSLETFITAGLFWIVFRRGKW 458


>pir||C69140 conserved hypothetical protein MTH314 - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2621368|gb|AAB84820.1| (AE000816) conserved protein
           [Methanobacterium thermoautotrophicum]
           Length = 452
           
 Score =  145 bits (361), Expect = 1e-33
 Identities = 114/435 (26%), Positives = 196/435 (44%), Gaps = 10/435 (2%)

Query: 10  EILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSL 69
           EI+ G   + L++L+ PLI+  L+  +YNL D  W+A LG   L+A G V P+   ++ L
Sbjct: 8   EIIRGDPRRALIKLSGPLIVAMLLTSIYNLVDAVWVAGLGGEALAAIGFVTPIYMILVGL 67

Query: 70  GSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVT 129
            +G      + VS+ +GAG+ +  +  A     + L +S++L  I  ++    L  +   
Sbjct: 68  SNGLGAGAASSVSRCLGAGDEEGMNNSASHTIIITLAVSIILTVIIEILLRDILLSLGAA 127

Query: 130 PDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIF 189
             + P A++Y   +FAG    L       +LR+ GD + P+    L+ +LN++LDP+ I+
Sbjct: 128 GALKP-AMEYGSVVFAGTLFTLFPGAAYGILRSEGDARRPMYAMGLSAVLNMVLDPILIY 186

Query: 190 ILDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIKTFKIGLPAS 249
               G+ GAA AT+IS+ + S++  Y    G+    I     R D  +      + +PAS
Sbjct: 187 TAGWGIAGAAWATVISQLLVSLLIIYWFLAGRTFTSIGWSHFRADRGVVWSILSVTIPAS 246

Query: 250 IGDSTNSFGFVLLNRIIYTY-GTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGA 308
                 S    LLN I+ +  GT A A Y+   R+          ++ A+ ++ G   G+
Sbjct: 247 AEFLVMSMVTALLNWILTSVAGTSAVAVYSAGWRIVMLAIVPVISVATALVSVSGVAYGS 306

Query: 309 ENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYFAASF 368
            N++        ++    LI      L       I   F         + ++  +     
Sbjct: 307 RNFENLEVAHGYSIRLGLLIAGATAALTFVLAPWIAWIFSYSQASSHLAPRITGFLRVIC 366

Query: 369 PFF-----GIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLG-DSAGVWIG 422
            F+     GI S   ++F  AG    +L+L +IR   L    +Y L  TLG    GVW G
Sbjct: 367 LFYIFLPPGIMSG--SIFQGAGRGMTSLMLSVIRQVLLVAVFAYLLAVTLGLGEVGVWWG 424

Query: 423 MGLSNVISALIGFAW 437
           +   ++  +L+ + W
Sbjct: 425 VVAGDIGGSLVAYLW 439


>pir||A69905 conserved hypothetical protein yoeA - Bacillus subtilis
           >gi|2634220|emb|CAB13720.1| (Z99113) similar to
           hypothetical proteins from B. subtilis [Bacillus
           subtilis] >gi|2634231|emb|CAB13730.1| (Z99114) similar
           to hypothetical proteins from B. subtilis [Bacillus
           subtilis]
           Length = 463
           
 Score =  139 bits (348), Expect = 5e-32
 Identities = 99/433 (22%), Positives = 202/433 (45%), Gaps = 9/433 (2%)

Query: 15  SIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAK-LGRSELSAPGTVWPLLWFMMSLGSGF 73
           S+ +++     PL+++N++Q +  L     + + LG   ++A  + +PL + ++S   G 
Sbjct: 17  SVWRSMSLFLVPLLLSNVLQSVGQLVGMMAVGRWLGVDAVAAVSSFFPLFFLLISFTIGI 76

Query: 74  VVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVY 133
                 ++ Q  GA   ++   V G+  +   +L ++LA IG + +   LR +    +V 
Sbjct: 77  GSGSSILIGQAYGAKNEERLKAVVGTTLTFTFLLGVVLAVIGSIFTLDILRLMGTPENVI 136

Query: 134 PYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIFIL-- 191
             +  Y   +F  +P       +   LR  GD+KTP    I++ ++NI L PV I  +  
Sbjct: 137 HVSANYARILFYAMPFMFLYFAYTTFLRGTGDSKTPFYTLIVSTVINIALLPVLILGMFG 196

Query: 192 --DMGVLGAAIATIISEGIGSIIGGYLLFTGKVGI---KISRDDLRPDVNLYIKTFKIGL 246
              +G+ G+A AT+IS     ++    L   K  +   K  R  L+ D  L +   ++G+
Sbjct: 197 FPKLGIYGSAYATVISTIATFLVLMVYLRKRKHPLQFDKTVRRYLKMDKELLVLLLRLGV 256

Query: 247 PASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNI 306
           PASI     S   + +   +  YG+ A A Y + N++ +++   A  +  A+     Q+I
Sbjct: 257 PASINMILVSLSEIAVISFVNHYGSNATAAYGVVNQVASYVQMPAVSLGIAVSIFAAQSI 316

Query: 307 GAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYFAA 366
           GA  + R ++V    +  N++I     +L   F  +I   F+ +   +  + +++     
Sbjct: 317 GANEFDRLKQVIRVGIWLNYIIGGVLIILIYVFSHQILSLFLTEQESLYIAHRLLMTTLW 376

Query: 367 SFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLG-TTLGDSAGVWIGMGL 425
           S+  FG    ++    ++G      ++ I  +WG+ +P+++ L   T  +  GVW+G   
Sbjct: 377 SYLLFGNAQIISATMRASGTVLWPTVISIFAIWGVEVPVAFVLSHYTKLEILGVWVGYPA 436

Query: 426 SNVISALIGFAWF 438
           +  +S L+ + ++
Sbjct: 437 AFAVSLLLIYGYY 449


>gb|AAG20342.1| (AE005107) DNA damage-inducible protein; DinF [Halobacterium sp.
           NRC-1]
           Length = 469
           
 Score =  136 bits (340), Expect = 4e-31
 Identities = 110/445 (24%), Positives = 197/445 (43%), Gaps = 14/445 (3%)

Query: 7   TREEILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFM 66
           +R+EI  GS+ + LL L  PL++   V V+  + D FWL ++ R+ +SA G V PL+  +
Sbjct: 5   SRDEITGGSLPRALLVLTAPLVVQQYVVVVQQIVDVFWLGRVSRNAVSAVGLVAPLIGLL 64

Query: 67  MSLGSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFI 126
               S   +    +V+Q++GA +   A         L+   +LLLA + + ++P  +  +
Sbjct: 65  ALATSVATIGCRVLVAQHVGADDAAAARSTGFHATVLVGAANLLLAVVVLWLAPDLVGVL 124

Query: 127 KVTPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPV 186
                V      Y+     G        T        GD++  + +N++ ++ N++LDP 
Sbjct: 125 LSDEAVIQLGATYLTVTTVGRVFGGMSDTIESGFVGWGDSRMSMLINVVAVLTNVVLDPF 184

Query: 187 FIF------ILDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIK 240
            +           G+ GAA+AT I    G  +    L        I R DL    +    
Sbjct: 185 LVVGWQLPGFAGYGIFGAALATAIGYVAGFTVAVAGLGVDSTSFTIGRADLGVSRDTVRS 244

Query: 241 TFKIGLPASIGDSTNSFGFVLLNRIIY-TYGTVAFATYTITNRLTNFMFAFADGISQAMG 299
              +G+P +  ++      +L+  I+    G+   A YTI  R+    F  A  +  A+ 
Sbjct: 245 LLSVGVPHAGQEAGRQIARLLVVAIVAGVAGSAGLAAYTIGARIATVAFVPAAAVGSAVS 304

Query: 300 TMVGQNIGAENYKRA-REVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGI-IKES 357
           ++VGQN+GA N  RA R   + A AT   + V G   + +    +  F     GI +  +
Sbjct: 305 SIVGQNVGAGNPDRATRATWLAAGATTAGMAVLGVAQYSSPATIVSVFAPTFSGIELTYT 364

Query: 358 EKVVKYFAASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPL----SYYLGTTL 413
              ++  A  +  FG+   +   F  AG T  +++  +++ WG+R+P+    +Y +  ++
Sbjct: 365 VAYLQILAVGYWAFGLIYPIQGGFNGAGKTTVSMVATLLQYWGVRLPVAALGAYVVVFSV 424

Query: 414 GDSAGVWIGMGLSNVISALIGFAWF 438
              A  W  +  SNV  A+   A+F
Sbjct: 425 PVHAAFW-AITASNVACAVGVTAYF 448


>pir||E70312 conserved hypothetical protein aq_128 - Aquifex aeolicus
           >gi|2982882|gb|AAC06502.1| (AE000675) hypothetical
           protein [Aquifex aeolicus]
           Length = 472
           
 Score =  135 bits (336), Expect = 1e-30
 Identities = 107/430 (24%), Positives = 184/430 (41%), Gaps = 9/430 (2%)

Query: 15  SIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSGFV 74
           S+ K +++L+ P+I+ NL+  + N+     ++ +  S ++A G    LLWF+ SL +   
Sbjct: 14  SVIKKVVKLSIPIIVVNLLYTVENMISMILVSSISPSAVAATGFSLSLLWFIYSLMALSY 73

Query: 75  VAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYP 134
                +++Q++GA +      + G   S L+ L L   G   V+  F ++ +  +  V  
Sbjct: 74  SGTNILIAQFVGAKKDPSPILINGLFLSFLISLPLFFYGKDFVL--FLMKVLGASETVRS 131

Query: 135 YALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIF----I 190
            A +Y+  IF  +P+    +TF      AGDTKTP+KV I+  + +I      I     +
Sbjct: 132 LAKEYLTPIFWFIPIGFLTNTFYGAYNGAGDTKTPMKVAIIMNLTHIGTAYTLINGKFGL 191

Query: 191 LDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIKTFKIGLPASI 250
             +GV GA     ISE +   I  +LL   K    +    LR +  L  K  ++G P ++
Sbjct: 192 PKLGVEGAGWGIAISEILAFFIYTFLLIFFKKPFPLH---LRLEPKLLFKMVRLGTPTAL 248

Query: 251 GDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAEN 310
             +  +  F +    +  +G    A + I  R+ +  F    G+  A  T+ GQN GA N
Sbjct: 249 ERAITTLSFNVFVGFLAKFGDKVLAAHQIGLRIESISFMIGFGVMIASTTLAGQNYGARN 308

Query: 311 YKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYFAASFPF 370
           Y+        +     L++    L+ + F   +   F  DP +I+ +   ++    S P 
Sbjct: 309 YRGMVHAVNTSAHFTALVMSLTGLILILFPHYLVYPFSRDPEVIEWASYYLQIVGISQPA 368

Query: 371 FGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLGDSAGVWIGMGLSNVIS 430
               S  +      G T   L + I   W  RI  SY+L   +      W  M     + 
Sbjct: 369 MAYASIYSGALKGMGKTHIPLFVNISSFWLFRIIPSYFLLKVIHSPLVPWGFMTFETAVR 428

Query: 431 ALIGFAWFLK 440
           AL  +  F K
Sbjct: 429 ALFYYTVFKK 438


>dbj|BAB06655.1| (AP001517) unknown conserved protein [Bacillus halodurans]
           Length = 452
           
 Score =  132 bits (328), Expect = 1e-29
 Identities = 113/433 (26%), Positives = 196/433 (45%), Gaps = 10/433 (2%)

Query: 19  TLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSGFVVAGF 78
           TL  L +P+ I  L+ ++    DT  L++     ++A G    +L  ++ +  GFV  G 
Sbjct: 10  TLFALTWPIFIEILLHMLMGNADTLMLSQYSDDAVAAVGVSNQILAVIIVM-FGFVATGT 68

Query: 79  A-MVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYPYAL 137
           + +V+Q++GA E + A +VA       L+  ++L  + I   P  L+ +++   +   A 
Sbjct: 69  SILVAQHLGAKERENAGKVAVVSIGANLIFGIVLGLLLIAFGPPILKAMQLDDSLLQEAT 128

Query: 138 KYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIF----ILDM 193
            Y+  +     V   + T   +LR+   TK  + V I   ILN+I + +FIF    I  +
Sbjct: 129 LYLQIVGGFSVVQSLIMTAGAILRSHSFTKDVMYVTIGMNILNVIGNYLFIFGPFGIPVL 188

Query: 194 GVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLR--PDVNLYIKTFKIGLPASIG 251
           GV G A++T++S  IG  +   LL+    G       L+  P V L     KIG+P++  
Sbjct: 189 GVTGVALSTVVSRTIGLFVIAILLYKRIRGELPFAYLLKRFPRVELR-NLLKIGIPSAGE 247

Query: 252 DSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAENY 311
             + +   +++   I   GT A  T   T  L  F+F FA  I Q    ++G  +GA+  
Sbjct: 248 QLSYNASQLVITYFIAMMGTEALTTKVYTQNLMMFVFLFAVAIGQGTQILIGHQVGAKQI 307

Query: 312 KRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYFAASFPFF 371
           + A     +++     + V   ++F AF   +   F ++P I+     ++       P  
Sbjct: 308 QAAYVRCFRSLWIAMTVSVSMAVVFFAFSTPLLGIFTDNPDILSLGTTLLLLTIILEPGR 367

Query: 372 GIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLG-DSAGVWIGMGLSNVIS 430
                V +   +AG  K  + L I+ +WG+ +P++Y LG  LG    GVWI         
Sbjct: 368 ACNLVVISSLRAAGDVKFPVYLAIVSMWGIAVPIAYLLGLPLGLGLIGVWIAFIADEWFR 427

Query: 431 ALIGFAWFLKGSW 443
            L+    + KG W
Sbjct: 428 GLLMIWRWRKGKW 440


>emb|CAA84073.1| (Z34303) DinF protein [Streptococcus pneumoniae]
           Length = 456
           
 Score =  131 bits (325), Expect = 2e-29
 Identities = 102/428 (23%), Positives = 192/428 (44%), Gaps = 20/428 (4%)

Query: 10  EILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAK-LGRSELSAPGTVWPL----LW 64
           +++ G I  +LL   +P++++N+ Q +YN  D   + + LG+  L+A G    +    + 
Sbjct: 8   DLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVGRFLGQESLAAVGATTAIFDLIVG 67

Query: 65  FMMSLGSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALR 124
           F + +G+G  +    ++++Y GA  + K      + + L  +LS+L+  +G +     L+
Sbjct: 68  FTLGVGNGMGI----VIARYYGARNFTKIKEAVAATWILGALLSILVMLLGFLGLYPLLQ 123

Query: 125 FIKVTPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILD 184
           ++    ++ P + +Y+  I   V V+   + F  +LR+ GD+   +   I + ++N++LD
Sbjct: 124 YLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLRSIGDSLAALGFLIFSALVNVVLD 183

Query: 185 PVFIFILDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIKTFKI 244
             FI  L +GV  A +ATIIS+G+ +++  Y +      +       + D +LY    + 
Sbjct: 184 LYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRKSVPELLPQFKHFKWDKSLYADLLEQ 243

Query: 245 GLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQ 304
           GL   +  S  S G V+L   + T+G V  +  T   R+  F       IS +M T   Q
Sbjct: 244 GLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQTAARRIMTFALLPMTAISASMTTFASQ 303

Query: 305 NIGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFI---NDPGIIKESEKVV 361
           N+GA+   R  +        +    VF   +F+ F       F+    D  +I+     +
Sbjct: 304 NLGAKRPDRIVQGLRIGSRLSISWAVF-VCIFLFFASPALVSFLASSTDGYLIENGSLYL 362

Query: 362 KYFAASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWG------LRIPLSYYLGTTLGD 415
           +  +  +P   +     N     G     L+   I L G      L IP + Y G  L +
Sbjct: 363 QISSTFYPILSLLLIYRNCLQGLGQKILPLVSSFIELIGKIVFVVLIIPWAGYKGVILCE 422

Query: 416 SAGVWIGM 423
              +W+ M
Sbjct: 423 PL-IWVAM 429


>pir||JC4561 DNA damage-inducible protein homolog - Pyrococcus sp
           >gi|971571|emb|CAA62487.1| (X91006) orf B [Pyrococcus
           sp.] >gi|1586540|prf||2204238A dinF-like gene
           [Pyrococcus sp.]
           Length = 363
           
 Score =  125 bits (311), Expect = 1e-27
 Identities = 97/330 (29%), Positives = 154/330 (46%), Gaps = 11/330 (3%)

Query: 16  IEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWP--LLWFMMSLGSGF 73
           I K L +LA+P I  N+ Q + NL DT  +  +    L     VW   + WFM  +    
Sbjct: 4   IRKRLWKLAWPAIAGNISQTLLNLVDTMIVGHVSAVALGC-SWVWEGMVSWFMFPIMMAV 62

Query: 74  VVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVY 133
                A+V++ +G   Y +ASRVA     +  +L + +   GI      LR +    +V+
Sbjct: 63  STGTLAVVARRVGERNYDEASRVAEQSMYIAFILGIPVMLFGIFFGDDILRIMGAKGEVF 122

Query: 134 PYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIF---- 189
             A  Y+  +F   P+      F   LR AGDTKTP+ +NIL  ++N +LD + +F    
Sbjct: 123 EIAYAYLRVLFLFYPIRFVGFAFFSSLRGAGDTKTPMLLNILMNVVNAVLDYLLVFGKLG 182

Query: 190 ILDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIKTFKIGLPAS 249
              MG +GAA A+ I   I  ++G YL    ++ +K   + LR   ++  K  +IG P  
Sbjct: 183 FPRMGPVGAAWASGIGITIAFLVGLYLFIAHRLVLKPVLE-LRIRWDIVEKILRIGTPTM 241

Query: 250 IGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGA- 308
           +     SF   L   I+  +G +A + + I  R+ +  +  A G S A   +VGQ++GA 
Sbjct: 242 LERGLFSFYNFLYMSIVTRFGKIALSAHHIGLRVESIAYMPAFGFSIATSALVGQSLGAK 301

Query: 309 --ENYKRAREVAIKAMATNFLILVFGTLLF 336
             E   R  + AIK       ++ F  + F
Sbjct: 302 KPEQRGRVVKEAIKMSPAFMSVMAFVLVAF 331


>pir||G82392 conserved hypothetical protein VCA0989 [imported] - Vibrio cholerae
           (group O1 strain N16961) >gi|9658430|gb|AAF96885.1|
           (AE004425) conserved hypothetical protein [Vibrio
           cholerae]
           Length = 444
           
 Score =  122 bits (304), Expect = 7e-27
 Identities = 103/448 (22%), Positives = 201/448 (43%), Gaps = 31/448 (6%)

Query: 13  SGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSG 72
           + S+ K L ++ +P++   L  + + L D+ ++ +LG   L+A G   P+   ++ +  G
Sbjct: 7   TSSLAKQLFQMTWPMLFGVLSLMSFQLVDSAFIGQLGVLPLAAQGFTMPIQMVIIGIQVG 66

Query: 73  FVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIK----- 127
             +A  A++S+ IGAG+ + A ++ G        L +++ GIG+ +    L  ++     
Sbjct: 67  LGIATTAVISRAIGAGKTEYAKQLGG--------LVIVIGGIGVALIALVLYLLRQPLLG 118

Query: 128 ---VTPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILD 184
                  V+     Y +   A       L+ +  V RA G+T  P  + ++T +LN+ILD
Sbjct: 119 LLGAPETVFAIIDHYWLWWLASAWTGAMLYFYYSVCRANGNTLLPGTLMMVTSVLNLILD 178

Query: 185 PVFIFILDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIKTFKI 244
           P+FIF  D+G+ GAAIATII+ G+G  I        KV  +        D+N+      +
Sbjct: 179 PIFIFTFDLGIDGAAIATIIAFGVGIAI-----VAPKVAQRQWTSYQWQDLNISQSLTAL 233

Query: 245 GL---PASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTM 301
           G    PA +         +   +++ ++GT A A + + +R   F       ++ ++  M
Sbjct: 234 GHIMGPAMLSQLLPPLSSMFATKLLASFGTAAVAAWALGSRFEFFALVAVLAMTMSLPPM 293

Query: 302 VGQNIGAENYKRAREVAIKA--MATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEK 359
           +G+ +GA+     R++   A      F +L+   L+   F   +     ++  + +    
Sbjct: 294 IGRMLGAKEITHIRQLVRIACQFVLGFQLLI--ALVTYVFATPLAELMTSETEVSQILNL 351

Query: 360 VVKYFAASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLGDSAGV 419
            +     S    GI   + +V  + G +   L +  +RL+   +P   +LG       G+
Sbjct: 352 HLVIVPISLGALGICMLMVSVANALGKSYVALTISALRLFAFYLP-CLWLGAHFYGIEGL 410

Query: 420 WIGMGLSNVISALIGFAWFLKGSWMRRI 447
           +IG  + N+I+     AW      +R++
Sbjct: 411 FIGALVGNIIAGWA--AWLAYQKALRQL 436


>pir||H69837 conserved hypothetical protein yisQ - Bacillus subtilis
           >gi|1934838|emb|CAB07959.1| (Z93940) unknown [Bacillus
           subtilis] >gi|2145382|emb|CAA70645.1| (Y09476) YisQ
           [Bacillus subtilis] >gi|2633417|emb|CAB12921.1| (Z99109)
           alternate gene name: yucE~similar to hypothetical
           proteins [Bacillus subtilis]
           Length = 455
           
 Score =  122 bits (302), Expect = 1e-26
 Identities = 100/435 (22%), Positives = 199/435 (44%), Gaps = 9/435 (2%)

Query: 19  TLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSGFVVAGF 78
           +L  L +P+ I   + +     DT  L++   + ++A G    +L  ++ + S       
Sbjct: 20  SLFSLTWPIFIEVSLYMFMGNADTLMLSQYSDNSVAAVGVSNQILNLIIVMFSFIATGTT 79

Query: 79  AMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYPYALK 138
            ++SQ++G+ + K+A  VA         +SL ++ +    +   L  + ++  + P A K
Sbjct: 80  VIISQFLGSRQKKEAMEVAYVSIGANFFISLAISAVVFFAAVPLLHMMGLSDALMPDA-K 138

Query: 139 YMIAIFAGVP-VALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIFILD----M 193
             + +  G+  +   + TF+ +L++ G TK  + V I   ILNI  + V IF L     +
Sbjct: 139 VFLQVVGGLSFIQALIMTFSAILKSYGYTKDTMFVTIGMNILNIAGNFVVIFGLFGFPVL 198

Query: 194 GVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYI-KTFKIGLPASIGD 252
           GV G A++T I+  IG +I   ++   ++ +K+S   +      ++ K  KIG+P++   
Sbjct: 199 GVAGVAMSTSIARVIG-LIAMIVIVNKRIQLKMSLKKVFHMHKEHLRKLLKIGIPSAGEQ 257

Query: 253 STNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAENYK 312
            + +   +++   I   G  A  T   T  +T F+  F   ISQ    ++G+ IG + + 
Sbjct: 258 LSYNLSQMIVTYFIAIMGAQALTTKVYTQNITMFILLFGTAISQGTQILIGRYIGGKQFD 317

Query: 313 RAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYFAASFPFFG 372
            A E  +K++     I    ++L   F +++   F   P II  +  ++       P   
Sbjct: 318 AAYERCMKSLYWALGIAAATSVLMTIFSKDLIGLFTQSPDIIATASLLIAMTIILEPGRS 377

Query: 373 IFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLG-DSAGVWIGMGLSNVISA 431
               + N   +AG  K  + + +I +WG+ +PL+Y  G  LG   AG+WI       +  
Sbjct: 378 FNVIIINSLRAAGDAKFPVYMAMISMWGIGLPLAYLFGIHLGFGLAGIWISFIADEWVRG 437

Query: 432 LIGFAWFLKGSWMRR 446
           ++ +  +    W+++
Sbjct: 438 ILMYRRWRSRIWIQK 452


>sp|P45272|YDHE_HAEIN HYPOTHETICAL PROTEIN HI1612 >gi|1074865|pir||B64173 hypothetical
           protein HI1612 - Haemophilus influenzae (strain Rd KW20)
           >gi|1574453|gb|AAC23256.1| (U32834) conserved
           hypothetical transmembrane protein [Haemophilus
           influenzae Rd]
           Length = 464
           
 Score =  119 bits (295), Expect = 7e-26
 Identities = 102/433 (23%), Positives = 200/433 (45%), Gaps = 23/433 (5%)

Query: 18  KTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSA---PGTVW-PLLWFMMSLGSGF 73
           K L++++ P+++  + Q    L DT    ++  ++++A     ++W PL++F    G G 
Sbjct: 14  KKLIKISLPILLAQIAQNSMGLADTIMAGRVSSTDMAAISIGASIWMPLMFF----GQGL 69

Query: 74  VVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVY 133
           ++A    +S   G+G++ + +        L+L +S+ L G+ I      L+++++   + 
Sbjct: 70  LLALPPTISYLNGSGQHHRIAHQVRQGIWLVLGVSIPL-GLLIYFCEIPLQYMQMESKMS 128

Query: 134 PYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIF---- 189
             A  Y+ A+  G+P  L L  F  +      TK  + +  L +++NI L+ +FI+    
Sbjct: 129 DLARDYLHAMLWGLPAYLMLINFRCLNDGIEKTKPAMVITFLGLLINIPLNYIFIYGKFG 188

Query: 190 ILDMGVLGAAIATIISEGIGSIIGGYLLFTG--KVGIKISRDDLR-PDVNLYIKTFKIGL 246
           +   G +G  IAT I      ++  +  +T   +  +K+    +  P+     K  ++GL
Sbjct: 189 MPAFGAVGCGIATAIVNWAMCLMMIFYSYTNTQERSLKVFSQLIEMPNPKTLKKLLRLGL 248

Query: 247 PASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNI 306
           P +I        + L + ++   G    A++ IT   ++F+F F   I  A   +VGQ +
Sbjct: 249 PIAIAICCEVALYALTSLMLSPLGATIVASHQITLNTSSFIFMFPMSIGMATTILVGQAL 308

Query: 307 GAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYFAA 366
           GA + + A+++   A+     + +   L+ + FR EI   F+ D  +I  +  ++  FAA
Sbjct: 309 GAGSPQNAKKIGYAALLLGLTVTIVTALITIFFRYEIASIFVTDEIVIAMAANLL-LFAA 367

Query: 367 SFPFFG-IFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLG-----DSAGVW 420
            + F   I   V  +      TK  L + +   W + +PL Y LG T       D+ G W
Sbjct: 368 LYQFSDTIQMVVGGILRGYKDTKVILYITLFSYWVIGVPLGYTLGRTDWLVPHIDAKGFW 427

Query: 421 IGMGLSNVISALI 433
           I   +S   +A +
Sbjct: 428 IAFVVSLTFAAFL 440


>pir||H71898 hypothetical protein jhp0696 - Helicobacter pylori (strain J99)
           >gi|4155262|gb|AAD06282.1| (AE001501) putative
           [Helicobacter pylori J99]
           Length = 417
           
 Score =  111 bits (275), Expect = 2e-23
 Identities = 100/415 (24%), Positives = 184/415 (44%), Gaps = 23/415 (5%)

Query: 43  FWLAKLGRSELSAPGTVWPLLWFMMSLGSGFVVAGFAMVSQYIGAGEYKKASRVAGSLY- 101
           F++ K+    + A G     L     + +       A++S+ +GA ++ + +    S++ 
Sbjct: 9   FFVGKISHHHIVALGVGLQFLMLFYGINTILYTGTNAILSRLVGARDFAQINHAFSSIFI 68

Query: 102 -SLLLMLSLLLAGIGIVISPFALRFIKVTPDVYPYALKYMIAIFAGVPVALTLHTFNFVL 160
            + ++ L +L A    +I PF L ++++          Y+  +   +P     +     L
Sbjct: 69  GAFVICLGVLFASY-FLIEPF-LNWMQLQDPSRQLTQDYLEVLVIALPSIFLKNVLVSAL 126

Query: 161 RAAGDTKTPVKVNILTIILNIILDPVFIF----ILDMGVLGAAIATIISEGIGSIIGGYL 216
            +  DT TP  V I+ +I  I L+   IF      +MG++G+A+A ++       +  + 
Sbjct: 127 ASFSDTLTPFIVKIIMVIACIFLNQALIFGDFGFKEMGIVGSALANVV-------VSYWE 179

Query: 217 LFTGKVGIKISRDDLRPDVNL---YIKT-FKIGLPASIGDSTNSFGFVLLNRIIYTYGTV 272
           L    + I+I +  L+  +     ++KT FK+G PA      + F  +LL++ + +YG  
Sbjct: 180 LLALSLWIQIKKIPLKFKITFHFSFLKTMFKVGWPAGFERLLSLFSLILLSKFVASYGDK 239

Query: 273 AFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAENYKRAREVAIKAMATNF-LILVF 331
             A   I  R+  F F    G   A   + GQN+GA   K A E A   +  +  L+ V 
Sbjct: 240 VLAGMQIGIRVETFSFMPGFGFMIAAMVLTGQNLGANKPKIATEYAHLILKISMGLMGVL 299

Query: 332 GTLLFMAFREEIFRFFINDPGIIKESEK-VVKYFAASFPFFGIFSAVTNVFASAGHTKKN 390
           G +L + F +E    F  D  +++ +   ++    +  P  G F  +  VF  AG +K +
Sbjct: 300 GVILIL-FAKEFASLFSQDGEVLEVARSYLIAVGLSQAPLIGYF-VLDGVFRGAGISKVS 357

Query: 391 LILGIIRLWGLRIPLSYYLGTTLGDSAGVWIGMGLSNVISALIGFAWFLKGSWMR 445
           L +  + LWGLRI   Y L         +++ + L   + + I +  F KG W R
Sbjct: 358 LYINTLSLWGLRIMPIYLLLIYHFKVEFIFVVIALETFLRSFIYYKVFSKGIWKR 412


>pir||E82296 conserved hypothetical protein VC0650 [imported] - Vibrio cholerae
           (group O1 strain N16961) >gi|9655087|gb|AAF93816.1|
           (AE004151) conserved hypothetical protein [Vibrio
           cholerae]
           Length = 445
           
 Score =  110 bits (273), Expect = 3e-23
 Identities = 97/428 (22%), Positives = 186/428 (42%), Gaps = 6/428 (1%)

Query: 11  ILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAK-LGRSELSAPGTVWPLLWFMMSL 69
           +++ SI +  +R   P +   LV  +Y + D  ++   +G   L+     WP++  ++ +
Sbjct: 1   MMNRSIYRQFVRYTIPTVAAMLVNGLYQVVDGIFIGHYVGAEGLAGINVAWPVIGTILGI 60

Query: 70  GSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVT 129
           G    V   A+ S   G G    A R+  +    LL+L+ ++A I   ++   LR+    
Sbjct: 61  GMLVGVGTGALASIKQGEGHPDSAKRILATGLMSLLLLAPIVAVILWFMADDFLRWQGAE 120

Query: 130 PDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIF 189
             V+   L+Y+  +  G    L      F+LR          + ++  + NI LD +FI 
Sbjct: 121 GRVFELGLQYLQVLIVGCLFTLGSIAMPFLLRNDHSPNLATLLMVIGALTNIALDYLFIA 180

Query: 190 ILDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIKTFKIGLPAS 249
            L   + GAAIAT +++ + +++G    F+ +  ++++R  LR + +   K F IG+ + 
Sbjct: 181 WLQWELTGAAIATTLAQVVVTLLGLAYFFSARANMRLTRRCLRLEWHSLPKIFAIGVSSF 240

Query: 250 IGDSTNSFGFVLLNRIIYTYG-TVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGA 308
              +  S    L N ++  YG  V    Y +   +    +   +GI+  M  +   + GA
Sbjct: 241 FMYAYGSTMVALHNTLMIEYGNAVMVGAYAVMGYIVTIYYLTVEGIANGMQPLASYHFGA 300

Query: 309 ENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFF-INDPGIIKESEKVVKYFAAS 367
            NY   R++   AM    L  +   L+   F E+    F  +D  +I  ++  +K    +
Sbjct: 301 RNYDHIRKLLRLAMGIAVLGGMAFVLVLNLFPEQAIAIFNSSDSELIAGAQMGIKLHLFA 360

Query: 368 FPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLGDSAGVWIGMGLSN 427
               G        + S     K + + +  +  + +P  + L    G   GVWI + +SN
Sbjct: 361 MYLDGFLVVSAAYYQSTNRGGKAMFITVGNM-SIMLPFLFILPQFFG-LTGVWIALPISN 418

Query: 428 -VISALIG 434
            V+S ++G
Sbjct: 419 IVLSTVVG 426


>pir||G64614 conserved hypothetical integral membrane protein HP0759 -
           Helicobacter pylori (strain 26695)
           >gi|2313885|gb|AAD07807.1| (AE000588) conserved
           hypothetical integral membrane protein [Helicobacter
           pylori 26695]
           Length = 417
           
 Score =  106 bits (262), Expect = 6e-22
 Identities = 94/413 (22%), Positives = 179/413 (42%), Gaps = 19/413 (4%)

Query: 43  FWLAKLGRSELSAPGTVWPLLWFMMSLGSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYS 102
           F++ K+    + A G     L     + +       A++S+ +GA ++ + +    S++ 
Sbjct: 9   FFVGKISHHHIVALGVGLQFLMLFYGINTILYTGTNAILSRLVGARDFTQINHAFSSIFI 68

Query: 103 LLLMLSLLLAGIG-IVISPFALRFIKVTPDVYPYALKYMIAIFAGVPVALTLHTFNFVLR 161
              M+ L +  +   +I PF L ++++          Y+  +   +P     +     L 
Sbjct: 69  GAFMICLGVLFVSYFLIEPF-LNWMQLQDPSRQLTQDYLEVLVVALPSIFLKNILVSALA 127

Query: 162 AAGDTKTPVKVNILTIILNIILDPVFIF----ILDMGVLGAAIATIISEGIGSIIGGYLL 217
           +  DT TP  V I+ +I  I L+   IF      +MG++G+A+A ++   +  +  G   
Sbjct: 128 SFSDTLTPFIVKIIMVIACIFLNQALIFGDFGFKEMGIVGSALANVVVSYLELLALG--- 184

Query: 218 FTGKVGIKISRDDLRPDVNL---YIKT-FKIGLPASIGDSTNSFGFVLLNRIIYTYGTVA 273
               V I+I +  L+  +     ++KT F++G PA      + F  +LL++ + +YG   
Sbjct: 185 ----VWIQIKKIPLKFKITFHFSFLKTMFRVGWPAGFERLLSLFSLILLSKFVASYGDKV 240

Query: 274 FATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAENYKRAREVAIKAMATNFLILVFGT 333
            A   I  R+  F F    G   A   + GQN+GA   K A E A   +  +  ++    
Sbjct: 241 LAGMQIGIRVETFSFMPGFGFMIAAMVLTGQNLGANKPKIATEYAHLILKISMGLMGVLG 300

Query: 334 LLFMAFREEIFRFFINDPGIIKESEK-VVKYFAASFPFFGIFSAVTNVFASAGHTKKNLI 392
           ++ + F +E    F  D  +++ +   ++    +  P  G F  +  VF  AG +K +L 
Sbjct: 301 IVLVLFAKEFASLFSQDEEVLEVARSYLIAVGLSQAPLIGYF-VLDGVFRGAGISKVSLY 359

Query: 393 LGIIRLWGLRIPLSYYLGTTLGDSAGVWIGMGLSNVISALIGFAWFLKGSWMR 445
           +  + LWGLRI   Y L         +++ +     + + I +  F KG W R
Sbjct: 360 INTLSLWGLRIMPIYLLLIHHFKVEFIFVVIASETFLRSFIYYKVFSKGIWKR 412


>gb|AAG10466.1|AF279106_28 (AF279106) predicted cation efflux pump [uncultured proteobacterium
           EBAC31A08]
           Length = 448
           
 Score =  102 bits (253), Expect = 6e-21
 Identities = 98/447 (21%), Positives = 192/447 (42%), Gaps = 15/447 (3%)

Query: 4   IERTREEILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLL 63
           +++  E+ L   I   L++++ P  +  L+  +  L + +++++LG + L+A    +P +
Sbjct: 1   MDKRTEQFLKDPIFPLLIKMSAPNTVAFLINAVVVLAEFWFISQLGITPLAAVTLAFPAI 60

Query: 64  WFMMSLGSGFVVAGF-AMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFA 122
                +  G +     + +++ +GA +  +A ++      +    +L    I  +     
Sbjct: 61  MLTQQMAFGALGGAVTSSIARSLGAADKPRAEKLLWHSLYISCFGALAFLIIFFIFGEPL 120

Query: 123 LRFIKVTPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNII 182
           LR +  T  +   +L Y      G  V     +    LR  GD + P  + ++   + + 
Sbjct: 121 LRILGGTGALLEESLAYCFVYLLGAIVVWLSGSLTAALRGMGDMQFPAVLTVICAGIQVF 180

Query: 183 LDPVFIF----ILDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLY 238
               FI     +  +G++G+A + I++ G  +++    + +    +++    L  +  L+
Sbjct: 181 FSAGFILGSFGLPKLGLVGSAWSMIVTSGFMALVTLIKISSPSSPVRLKLKRLTIERELF 240

Query: 239 IKTFKIGLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAM 298
              F + LPAS+         +LL  +I  +GT A A Y I +R+   +     GI  AM
Sbjct: 241 EDIFSVALPASLSPIMTVATVLLLTGLIGQFGTSAIAGYGIGSRVEFLLIPIVFGIGTAM 300

Query: 299 GTMVGQNIGAENYKRAREVA-IKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKES 357
             MVG NIGA+N +RA ++  + A     L  V G  L +     I   F +DP  +  +
Sbjct: 301 TAMVGTNIGAKNIERAEKIGMVGATTAGLLSAVIGLALALTPNLWI-SIFTSDPETLLVT 359

Query: 358 EKVVKYFAASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIP-------LSYYLG 410
           ++ ++     + F G   ++      A   K  +I+  IRL    +        LSY L 
Sbjct: 360 KQYIQILGVCYVFQGYGLSLYFASQGANAMKWPIIITAIRLIVFSVIALVAVYWLSYGLV 419

Query: 411 TTLGDSAGVWIGMGLSNVISALIGFAW 437
           +    SA   +  G+  VIS  +G AW
Sbjct: 420 SIFYASAIAMVIFGILMVISLKMG-AW 445


>pir||A71849 hypothetical protein jhp1110 - Helicobacter pylori (strain J99)
           >gi|4155699|gb|AAD06682.1| (AE001538) putative
           [Helicobacter pylori J99]
           Length = 459
           
 Score =  101 bits (250), Expect = 1e-20
 Identities = 96/428 (22%), Positives = 186/428 (43%), Gaps = 16/428 (3%)

Query: 15  SIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAK-LGRSELSAPGTVWPLLWFMMSLGSGF 73
           SI K       PL+ + +    Y++ D  ++ K LG+  ++A    WP+   +++    F
Sbjct: 12  SIRKLFFYYFIPLVFSMISLSTYSMVDGMFVGKKLGKEAIAAVNIAWPIFPGLIAYELLF 71

Query: 74  VVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVY 133
                ++V  ++G  +  +A  V  S++  + + + +L+   +  S    RF      + 
Sbjct: 72  GFGAASIVGYFLGQNKTHRARLVFSSVFYFVALSAFILSMALLPFSENIARFFGSNDALL 131

Query: 134 PYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTII---LNIILDPVFIFI 190
             + +Y+  I  G  V + LH    V     + K PV   +  +I    NI  + +FIF+
Sbjct: 132 SMSKRYIEIILMG-SVFMVLHPLADVFVV--NDKRPVLAMVAMLIGSLANIFFNYLFIFV 188

Query: 191 LDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIKTFKIGLPASI 250
           L++GV G+AIAT+I   IG ++     +  K  +   +   R  ++  I + K G+P S 
Sbjct: 189 LEVGVQGSAIATVIGHAIGVLVLMQHFWRKKGQLYFIK---RFSLSSVISSAKSGVPQST 245

Query: 251 GDSTNSFGFVLLN-RIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAE 309
            + + S   +L N  I++T G    + Y I        F     ISQ +  +   + GA 
Sbjct: 246 AEFSASIMILLFNTAIMHTAGERFVSMYGIVMYNAIIFFTTLFAISQGIQPIASFSYGAR 305

Query: 310 NYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFI----NDPGIIKESEKVVKYFA 365
           N +R R V +  +   F I +F    +    E + + ++     D   ++E+++ +  + 
Sbjct: 306 NLERVRAVFVFGLKAAFCIGIFFYGAYYFLDEFLIKLYLQPSEQDALFMQETKRAMNIYY 365

Query: 366 ASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLGDSAGVWIGMGL 425
             + F G+       F S   TK + I+ I    G  + L   L    G + G+W+   +
Sbjct: 366 VGYVFLGMTLLCAVFFQSIQRTKSSFIITISHTLGFIVILLPILSHFYGVN-GIWVTYPI 424

Query: 426 SNVISALI 433
           +  ++ L+
Sbjct: 425 AQFLAFLV 432


>gb|AAG20494.1| (AE005121) DNA damage-inducible protein; Dip1 [Halobacterium sp.
           NRC-1]
           Length = 513
           
 Score =  100 bits (246), Expect = 4e-20
 Identities = 97/410 (23%), Positives = 177/410 (42%), Gaps = 18/410 (4%)

Query: 23  LAYPLIINNLVQVMYNLTDTFWLA-KLGRSELSAPGTVWPLLWFMMSLGSGFVVAGFAMV 81
           LA P ++   ++ +    D F ++   G + ++A    +   +    L         ++V
Sbjct: 35  LAVPAMVTGGLRTLLRTADFFMVSIATGSTAVAALEIGFQYYFIPFGLALALTSGTISVV 94

Query: 82  SQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYPYALKYMI 141
           S++ GA ++  A+        L L++SL +     V +   +  +   P++      Y+ 
Sbjct: 95  SRFKGADDHAGANFAIKQSLWLALLVSLPITAGTWVYADSMIGLLNSNPEIIELGAAYLR 154

Query: 142 AIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIFIL----DMGVLG 197
            +   V       T +  L  AGDT+TP+ V ++T+  NI L+ V IF +    ++GV+G
Sbjct: 155 VVMLTVVFRFWGMTASRALAGAGDTRTPMYVRLITLPTNIALNAVLIFGIWVFPELGVVG 214

Query: 198 AAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIKTFKIGLPASIGDSTNSF 257
           AA  T I+  +  I+   +L +G+  + +S    + D  +  +  ++ LP +    + +F
Sbjct: 215 AAWGTAIANAVAGIVFFAVLLSGRWDVTLSFSGKQWDWGVASEIVRVSLPLAGTRLSRTF 274

Query: 258 GFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAENYKRAR-- 315
           G      ++  +     A Y I  R+       A G S A  T+VGQ +GA +   A   
Sbjct: 275 GRFPFLFVLGLFSHQVVAAYAIGRRVMLLALMPAWGYSTASSTLVGQQLGAGDPDEAAAY 334

Query: 316 --EVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYFAASFPFFGI 373
             +    A+AT    L+ G LLF+A       F    P     +   ++ F  S   F +
Sbjct: 335 GWQTLRVALATQ---LIIGALLFVAAGPIASAF---TPERFSLTVTFIRIFGLSVAGFSV 388

Query: 374 FSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLGD--SAGVWI 421
              +      AG T+  L  G+I  + +R+PL+ +L    G   SAG W+
Sbjct: 389 ARTLRGALRGAGDTRWPLYGGLIGTYIVRLPLA-FLALDPGQIISAGPWV 437


>pir||C72561 hypothetical protein APE1773 - Aeropyrum pernix (strain K1)
           >gi|5105463|dbj|BAA80776.1| (AP000062) 423aa long
           hypothetical protein [Aeropyrum pernix]
           Length = 423
           
 Score = 99.1 bits (243), Expect = 9e-20
 Identities = 93/398 (23%), Positives = 170/398 (42%), Gaps = 16/398 (4%)

Query: 39  LTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSGFVVAGFAMVSQYIGAGEYKKASRVAG 98
           + DT+++  LG   ++A G    L+W  M   +   +    ++ Q IG+G      R AG
Sbjct: 12  IVDTYFVGGLGSESIAAVGAAGYLIWLYMVFSTLVYMGVLVILGQAIGSGNRGLVERAAG 71

Query: 99  SLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYPYALKYMIAIFAGVPVALTLHTFNF 158
              +L ++LS+++       S   L  + + P+V   A +Y+      V +      ++ 
Sbjct: 72  EGLTLSILLSIIVCAAAFAASKQLL--VVLAPEVDQLAWEYLSVSLLTVALHYVTILYDA 129

Query: 159 VLRAAGDTKTPVKVNILTIILNIILDPVFIF----ILDMGVLGAAIATIISEGIGSIIGG 214
           V RA G T   +  + +  + N  LDP+ I+       +GV GAA A++ +  +G ++  
Sbjct: 130 VFRALGKTMPILYSSGVFTLANTALDPILIYGRLGAPALGVEGAAWASVAASLLGLLVLV 189

Query: 215 YLLFTGKVGIKISRDDLRPDVNLYIKTFKIGLPASIGDSTNSFGFVLLNRIIYTYGTVAF 274
           YL     VG++     LRP  ++      +G P+ +       G V+    +   G  A 
Sbjct: 190 YLSRYLDVGLR----PLRP-TSVSRSILALGFPSMVERVVFVVGNVVYLGSVSRCGADAL 244

Query: 275 ATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAENYKRAREVAIKAMATNFLI-LVFGT 333
           A +TI  R+ +  F     I+ A G MVG  +GA     ++    + +  + LI LV G 
Sbjct: 245 AAHTIGVRIESLAFLPLFSIATASGVMVGWEVGAGRIAESKSTGWELIKLSSLIGLVVGA 304

Query: 334 LLFMAFREEIFRFFINDPGIIKESEKVVKYFAASFPFFGIFSAVTNVFASAGHTKKNLIL 393
            L +     +   F  DP +   +   +     + P  G+      +  +AG T+   ++
Sbjct: 305 ALALG-GWLVTPIFTGDPRVAWLAALYLVIAGLTEPLLGVVMVAGQIIRNAGDTRTPTLV 363

Query: 394 GIIRLWGLRIPLSYYLGTTLGDS---AGVWIGMGLSNV 428
            +  L+ LR+  +Y L   +       G W+ MG+  V
Sbjct: 364 NLGSLYILRVVPAYLLPGLMPTGLCVLGAWLAMGIDIV 401


>pir||H64667 conserved hypothetical integral membrane protein HP1184 -
           Helicobacter pylori (strain 26695)
           >gi|2314344|gb|AAD08230.1| (AE000624) conserved
           hypothetical integral membrane protein [Helicobacter
           pylori 26695]
           Length = 459
           
 Score = 97.9 bits (240), Expect = 2e-19
 Identities = 96/429 (22%), Positives = 187/429 (43%), Gaps = 20/429 (4%)

Query: 16  IEKTLLRLAYPLIINNLVQVMYNLTDTFWLAK-LGRSELSAPGTVWPLLWFMMSLGSGFV 74
           I K       PL  + +    Y++ D  ++ K LG+  ++A    WP+   +++    F 
Sbjct: 13  IRKLFFYYFIPLAFSMISLSTYSMIDGMFVGKKLGKEAIAAVNIAWPIFPGLIAYELLFG 72

Query: 75  VAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYP 134
               ++V  ++G  +  +A  V  S++  + + + +L+   +  S    RF      +  
Sbjct: 73  FGAASIVGYFLGQNKTHRARLVFSSVFYFVAISAFILSMALLPFSETIARFFGSNDALLS 132

Query: 135 YALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTII---LNIILDPVFIFIL 191
            + +Y+  I  G  V + LH    V     + K P+   +  +I    NI  + +FIF+L
Sbjct: 133 MSKRYIEIILMGA-VFMVLHPLADVFVV--NDKRPILAMVAMLIGSLANIFFNYLFIFVL 189

Query: 192 DMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIKTFKIGLPASIG 251
            +GV G+AIAT+I   IG ++     +  K  +   +   R  ++  I + K G+P S  
Sbjct: 190 KVGVQGSAIATVIGHAIGVLVLMQHFWRKKGQLYFIK---RFSLSSVISSAKSGVPQSTA 246

Query: 252 DSTNSFGFVLLN-RIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAEN 310
           + + S   +L N  I++T G    + Y I        F     ISQ +  +   + GA N
Sbjct: 247 EFSASVMILLFNTAIMHTAGERFVSMYGIVMYNAIIFFTTLFAISQGIQPIASFSYGARN 306

Query: 311 YKRAREVAIKAMATNFL--ILVFGTLLFMAFREEIFRFFI----NDPGIIKESEKVVKYF 364
            +R +EV +  +   F   I+ +G   F+   E + + ++     DP  ++E+++ +  +
Sbjct: 307 LERVKEVFVFGLKAAFCIGIVFYGAYYFL--DEFLIKLYLQPSEQDPLFMQETKRAMNIY 364

Query: 365 AASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLGDSAGVWIGMG 424
              + F G+       F S   TK + I+ +    G  + L   L    G + GVW+   
Sbjct: 365 YVGYIFLGMTLLCAVFFQSIQRTKSSFIITLSHTLGFIVILLPILSHFYGIN-GVWVTYP 423

Query: 425 LSNVISALI 433
           ++  ++ L+
Sbjct: 424 IAQFLAFLV 432


>pir||H81402 probable integral membrane protein Cj0560 [imported] -
           Campylobacter jejuni (strain NCTC 11168)
           >gi|6968028|emb|CAB75196.1| (AL139075) putative integral
           membrane protein [Campylobacter jejuni]
           Length = 442
           
 Score = 97.5 bits (239), Expect = 3e-19
 Identities = 87/415 (20%), Positives = 173/415 (40%), Gaps = 21/415 (5%)

Query: 18  KTLLRLAYPLIINNLVQVMYNLTDTFWLAK-LGRSELSAPGTVWPLLWFMMSLGSGFVVA 76
           +  ++ A P +I+      Y + D  ++ K LG   L+A   + P +    +L     + 
Sbjct: 12  RLFVKYAVPNVISMAFISFYYIVDGIFVGKYLGSDALAALALIIPFIMMSFALADMIAIG 71

Query: 77  GFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYPYA 136
               +S ++G G+   A ++  S   ++ ++S  +  +   + P  +  + V+ ++    
Sbjct: 72  SAVQISMHLGLGKKNLARKIFSSSMLIIFIISCFIGILEYFLGPVLIDCLNVSDEIKTMT 131

Query: 137 LKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIFILDMGVL 196
            + M       P  +     +  LR  G T   + +N++  + NI+LD +FI  L  G+ 
Sbjct: 132 KECMFVFALFAPFTMLSFALDNYLRICGKTAYSMVMNVIIALSNIVLDYIFIVELGWGLF 191

Query: 197 GAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIKTFKIGLPASIGDSTNS 256
            AA+AT +   +G I G +      + +KIS   L  ++ ++      G     G+ + S
Sbjct: 192 SAALATCLGLVLGGIFGIFPFLFQNLELKIS--SLYMNLKIFKNILYNGSSEFFGNISGS 249

Query: 257 FGFVLLNRIIYTYG-TVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAENYKRAR 315
              +  N ++     T A A ++I   + +F+      I  AM   +  N   +++ R +
Sbjct: 250 LYSIFANFVLLKISDTQAVAAFSIVLYIDSFIIMLIIAIGDAMQPALSYNYAKKDFSRIK 309

Query: 316 EVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYFA-------ASF 368
            +          + +F  +L + F E +   F       KE+ +  K FA       A  
Sbjct: 310 AIIKVVFFAGGFLSLFSIVLILIFGENLITLF------TKENNQEFKTFAYTALMLFAFN 363

Query: 369 PFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSY--YLGTTLGDSAGVWI 421
            FF  F+ ++  F +A   K +  L +     L IPL +  +L   +G + GVW+
Sbjct: 364 YFFAWFNVLSGSFLTA-FNKASFSLVLSLAQNLFIPLFFLLFLSCFMGLN-GVWL 416


>pir||H82186 probable multidrug resistance protein NorM VC1540 [imported] -
           Vibrio cholerae (group O1 strain N16961)
           >gi|9656046|gb|AAF94694.1| (AE004232) multidrug
           resistance protein NorM, putative [Vibrio cholerae]
           Length = 461
           
 Score = 97.1 bits (238), Expect = 4e-19
 Identities = 94/426 (22%), Positives = 180/426 (42%), Gaps = 25/426 (5%)

Query: 20  LLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSGFVVAGFA 79
           L++LA P++I ++ Q      DT     +   +++A      +    +  G G ++A   
Sbjct: 15  LIKLATPVLIASVAQTGMGFVDTIMAGGVSAIDMAAVSIAASIWLPSILFGVGLLMALVP 74

Query: 80  MVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYPYALKY 139
           +V+Q  GAG   K          L L++S+ +  + +  + F +RF+ V   +    + Y
Sbjct: 75  VVAQLNGAGRQHKIPFEVHQGLILALLVSVPIIAV-LFQTQFIIRFMDVEEAMATKTVGY 133

Query: 140 MIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIF----ILDMGV 195
           M A+   VP  L              TK  + +  + ++LNI L+ +F++      ++G 
Sbjct: 134 MHAVIFAVPAYLLFQALRSFTDGMSLTKPAMVIGFIGLLLNIPLNWIFVYGKFGAPELGG 193

Query: 196 LGAAIATIISEGIGSIIGGYLLFTGK--VGIKISRDDLRPDVNLYIKTFKIGLPASIGDS 253
           +G  +AT I   I  ++  + + T K    +K+     +P     I+ F++G P +    
Sbjct: 194 VGCGVATAIVYWIMLLLLLFYIVTSKRLAHVKVFETFHKPQPKELIRLFRLGFPVAAALF 253

Query: 254 TNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAENYKR 313
                F ++  ++   G+   A + +    ++ +F F   I  A+   VG  +G ++ K 
Sbjct: 254 FEVTLFAVVALLVAPLGSTVVAAHQVALNFSSLVFMFPMSIGAAVSIRVGHKLGEQDTKG 313

Query: 314 AREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYFAASFPFFGI 373
           A   A   + T         LL + FRE+I   +  +  ++  + +++ + A     +  
Sbjct: 314 AAIAANVGLMTGLATACITALLTVLFREQIALLYTENQVVVALAMQLLLFAA----IYQC 369

Query: 374 FSAVTNVFASAGHTKKNLIL----GIIRLWGLRIPLSYYLGTT-------LGDSAGVWIG 422
             AV  V A +    K++        I  W L +P  Y LG T       LG + G W+G
Sbjct: 370 MDAVQVVAAGSLRGYKDMTAIFHRTFISYWVLGLPTGYILGMTNWLTEQPLG-AKGFWLG 428

Query: 423 --MGLS 426
             +GLS
Sbjct: 429 FIIGLS 434


>dbj|BAA15804.1| (D90837) ORF_ID:o347#5~similar to [SwissProt Accession Number
           P45272] [Escherichia coli]
           Length = 546
           
 Score = 96.3 bits (236), Expect = 6e-19
 Identities = 94/432 (21%), Positives = 177/432 (40%), Gaps = 10/432 (2%)

Query: 23  LAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSGFVVAGFAMVS 82
           LA P+ + N   ++  +  TF ++ LG+  ++  G        +M+  +   +    +V+
Sbjct: 96  LAVPIFMENACVLLMGVLSTFLVSWLGKDAMAGVGLADSFNMVIMAFFAAIDLGTTVVVA 155

Query: 83  QYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIK--VTPDVYPYALKYM 140
             +G  + ++A         ++ + ++LLA +        + F+    T +V   AL Y+
Sbjct: 156 FSLGKRDRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAGDATTEVKALALTYL 215

Query: 141 IAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIFIL----DMGVL 196
                  P A      +  LR AG+TK P+ +N    ILNII+  + I+ L     +G +
Sbjct: 216 ELTVLSYPAAAITLIGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSWPGLGFV 275

Query: 197 GAAIATIISEGIGSIIGGYLLFTG-KVGIKISRDDLRPDVNLYI--KTFKIGLPASIGDS 253
           GA +   IS  IG++   ++L  G    ++IS       +N  I  +   IG+PAS+   
Sbjct: 276 GAGLGLTISRYIGAVAILWVLAIGFNPALRISLKSYFKPLNFSIIWEVMGIGIPASVESV 335

Query: 254 TNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAENYKR 313
             + G +L    +   GT   A   I   +   +      +  A   + G+ +G     +
Sbjct: 336 LFTSGRLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGSALGSASTIITGRRLGVGQIAQ 395

Query: 314 AREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYFAASFPFFGI 373
           A          + L L     L   F   +  F+  DP +      ++   A   P +  
Sbjct: 396 AEIQLRHVFWLSTLGLTAIAWLTAPFAGVMASFYTQDPQVKHVVVILIWLNALFMPIWSA 455

Query: 374 FSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLG-DSAGVWIGMGLSNVISAL 432
              +   F  A   +  + + ++ +WG R+ + Y LG  LG    GVW+GM     + A+
Sbjct: 456 SWVLPAGFKGARDARYAMWVSMLSMWGCRVVVGYVLGIMLGWGVVGVWMGMFADWAVRAV 515

Query: 433 IGFAWFLKGSWM 444
           + +   + G W+
Sbjct: 516 LFYWRMVTGRWL 527


>sp|P76352|YEEO_ECOLI HYPOTHETICAL 60.1 KDA PROTEIN IN AMN-CBL INTERGENIC REGION
           >gi|7466643|pir||B64963 membrane protein yeeO -
           Escherichia coli >gi|2367126|gb|AAC75048.1| (AE000290)
           orf, hypothetical protein [Escherichia coli K12]
           Length = 547
           
 Score = 96.3 bits (236), Expect = 6e-19
 Identities = 94/432 (21%), Positives = 177/432 (40%), Gaps = 10/432 (2%)

Query: 23  LAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSGFVVAGFAMVS 82
           LA P+ + N   ++  +  TF ++ LG+  ++  G        +M+  +   +    +V+
Sbjct: 97  LAVPIFMENACVLLMGVLSTFLVSWLGKDAMAGVGLADSFNMVIMAFFAAIDLGTTVVVA 156

Query: 83  QYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIK--VTPDVYPYALKYM 140
             +G  + ++A         ++ + ++LLA +        + F+    T +V   AL Y+
Sbjct: 157 FSLGKRDRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAGDATTEVKALALTYL 216

Query: 141 IAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIFIL----DMGVL 196
                  P A      +  LR AG+TK P+ +N    ILNII+  + I+ L     +G +
Sbjct: 217 ELTVLSYPAAAITLIGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSWPGLGFV 276

Query: 197 GAAIATIISEGIGSIIGGYLLFTG-KVGIKISRDDLRPDVNLYI--KTFKIGLPASIGDS 253
           GA +   IS  IG++   ++L  G    ++IS       +N  I  +   IG+PAS+   
Sbjct: 277 GAGLGLTISRYIGAVAILWVLAIGFNPALRISLKSYFKPLNFSIIWEVMGIGIPASVESV 336

Query: 254 TNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAENYKR 313
             + G +L    +   GT   A   I   +   +      +  A   + G+ +G     +
Sbjct: 337 LFTSGRLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGSALGSASTIITGRRLGVGQIAQ 396

Query: 314 AREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYFAASFPFFGI 373
           A          + L L     L   F   +  F+  DP +      ++   A   P +  
Sbjct: 397 AEIQLRHVFWLSTLGLTAIAWLTAPFAGVMASFYTQDPQVKHVVVILIWLNALFMPIWSA 456

Query: 374 FSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLG-DSAGVWIGMGLSNVISAL 432
              +   F  A   +  + + ++ +WG R+ + Y LG  LG    GVW+GM     + A+
Sbjct: 457 SWVLPAGFKGARDARYAMWVSMLSMWGCRVVVGYVLGIMLGWGVVGVWMGMFADWAVRAV 516

Query: 433 IGFAWFLKGSWM 444
           + +   + G W+
Sbjct: 517 LFYWRMVTGRWL 528


>pir||T36597 hypothetical protein SCH24.32c - Streptomyces coelicolor
           >gi|4808406|emb|CAB42738.1| (AL049826) hypothetical
           protein [Streptomyces coelicolor A3(2)]
           Length = 448
           
 Score = 96.3 bits (236), Expect = 6e-19
 Identities = 90/435 (20%), Positives = 178/435 (40%), Gaps = 18/435 (4%)

Query: 17  EKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSGFVVA 76
           ++ ++ LA P     + + ++ + D+  +  LG ++L+  G    LL   +S+      A
Sbjct: 19  DREIVALAVPAFGALVAEPLFVMADSAIVGHLGTAQLAGLGIASALLTTAVSVFVFLAYA 78

Query: 77  GFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYPYA 136
             A VS+ +GAG  + A R       L L+L   +  + +  +P  +     +    PYA
Sbjct: 79  TTAAVSRRVGAGNLQAAIRQGMDGIWLALLLGAAVVAVFLPAAPSLVELFGASDTAAPYA 138

Query: 137 LKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIFILDMGVL 196
             Y+     G+P  L +     VLR   +T+TP+ V +   I N +L+ + ++   +G+ 
Sbjct: 139 TTYLRISSLGIPAMLVVLASTGVLRGLQNTRTPLYVAVAGFIANAVLNVLLVYGAGLGIA 198

Query: 197 GAAIATIISE-GIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIKTFKIGLPASIGDSTN 255
           G+A  T+I++ G+ ++     L+    G +     LRPD+     + + G+P  +   + 
Sbjct: 199 GSAWGTVIAQCGMAAV----YLWVVVRGARQHGASLRPDLVGIRASAQAGMPLLVRTLSL 254

Query: 256 SFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAENYKRAR 315
               ++   +    G    A + I   L + +    D I+ A   ++G+ +GA++ + AR
Sbjct: 255 RAILMIATAVAARLGDADIAAHQIVLSLWSLLAFALDAIAIAGQAIIGRYLGADDAQGAR 314

Query: 316 EVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYFAASFPFFGIFS 375
           E   + +     + V   LL +  R      F  D  +   +   +   A + P  G+  
Sbjct: 315 EACRRMVEWGVAVGVVLGLLVVLSRPVFLPLFTGDSMVTDAALPALVIVAVAQPVCGVVF 374

Query: 376 AVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTL------GDSAGVWIGMGLSNVI 429
            +  V   AG        G    W + + L+ +    L      G    +W  M L   +
Sbjct: 375 VLDGVLMGAGD-------GPYLAWAMLLTLAVFTPAALLVPTLGGGLTALWAAMTLMMAM 427

Query: 430 SALIGFAWFLKGSWM 444
             +  +     G W+
Sbjct: 428 RLVTLWLRTRSGRWI 442


>dbj|BAA31456.1| (AB010463) NorM [Vibrio parahaemolyticus]
           Length = 456
           
 Score = 94.4 bits (231), Expect = 2e-18
 Identities = 87/431 (20%), Positives = 189/431 (43%), Gaps = 22/431 (5%)

Query: 19  TLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSGFVVAGF 78
           +L++LA P++I ++ Q      DT     + +++++A      +    +  G G ++A  
Sbjct: 10  SLIKLATPVLIASVAQTGMGFVDTVMAGGVTQTDMAAVSVASSIWLPSILFGIGLLMALV 69

Query: 79  AMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYPYALK 138
            +V+Q  G+   +K          L L++S+ + G+ ++ + F L+ + V   +    + 
Sbjct: 70  PVVAQLNGSARREKIPFEIQQGVVLALLISIPIIGV-LLQTQFILQLMDVEAVMADKTVG 128

Query: 139 YMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIF----ILDMG 194
           Y+ A+   VP  L   T          TK  + +  + ++LNI L+ +F++      ++G
Sbjct: 129 YIHAVIFAVPAFLLFQTLRSFTDGMSLTKPAMVIGFIGLLLNIPLNWIFVYGKFGAPELG 188

Query: 195 VLGAAIA-TIISEGIGSIIGGYLLFTGKV-GIKISRDDLRPDVNLYIKTFKIGLPASIGD 252
            +G  +A TI+   + +++  Y++ + ++  I +  +  +P     ++ FK+G P +   
Sbjct: 189 GVGCGVATTIVYWVMFALLLAYVMTSSRLKSINVFGEYHKPQWKAQVRLFKLGFPVAAAL 248

Query: 253 STNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAENYK 312
                 F ++  ++   G +  A + +    ++ +F     +  A+   VG  +G EN  
Sbjct: 249 FFEVTLFAVVALLVSPLGPIIVAAHQVAINFSSLVFMLPMSVGAAVSIRVGHRLGEENVD 308

Query: 313 RAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYFAASFPFFG 372
            AR  +   +     +     ++ +  RE I   + N+P +I  + +++ + A     + 
Sbjct: 309 GARVASRVGIMVGLALATITAIITVLSRELIAELYTNNPEVITLAMQLLLFAAV----YQ 364

Query: 373 IFSAVTNVFASA--GHTKKNLILG--IIRLWGLRIPLSYYLGTT------LGDSAGVWIG 422
              AV  + A A  G+     I     I  W L +P  Y LG T      +G + G W+G
Sbjct: 365 CTDAVQVIAAGALRGYKDMRAIFNRTFIAYWILGLPTGYILGRTDWIVEPMG-AQGFWLG 423

Query: 423 MGLSNVISALI 433
             +    +AL+
Sbjct: 424 FIIGLTAAALM 434


>pir||B83476 probable transporter PA1361 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9947303|gb|AAG04750.1|AE004565_9
           (AE004565) probable transporter [Pseudomonas aeruginosa]
           Length = 477
           
 Score = 92.1 bits (225), Expect = 1e-17
 Identities = 103/412 (25%), Positives = 169/412 (41%), Gaps = 28/412 (6%)

Query: 18  KTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPG---TVWPLLWFMMSLGSGFV 74
           K LL LA P++I  L        D     +    +L+A     ++W  ++ +M+   G +
Sbjct: 19  KELLTLAAPIMIAQLATTAMGFVDAVMAGRASPHDLAAVALGNSIWIPMFLLMT---GTL 75

Query: 75  VAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYP 134
           +A  A V+Q  GAG+      +      L L++  L   +   +S   L  +KV P++  
Sbjct: 76  LATTAKVAQRHGAGDQPGTGPLVRQALWLALLIGPLSGAVLWWLSEPILGLMKVRPELIG 135

Query: 135 YALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIF----I 190
            +L Y+  I  G P A   H         G T+  + + I  ++LNI ++   I+    +
Sbjct: 136 PSLLYLKGIALGFPAAALYHVLRCYTNGLGRTRPSMVLGIGGLLLNIPINYALIYGHFGM 195

Query: 191 LDMGVLGAAIATIISEGIGSIIG----GYLLFTGKVGI-KISRDDLR---PDVNLYIKTF 242
             MG  G   AT      GS++     G L +  K  I + S+   R   PD        
Sbjct: 196 PKMGGPGCGWAT------GSVMWFMFLGMLFWVNKASIYRASQLFSRWEWPDRATIGPLV 249

Query: 243 KIGLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMV 302
            +GLP  I     S  F ++  +I        A + I    +  +F     +  A+   V
Sbjct: 250 AVGLPIGIAVFAESSIFSVIALLIGGLDENVVAGHQIALNFSALVFMIPYSLGMAVTVRV 309

Query: 303 GQNIGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVK 362
           G N+GA   + AR  A   MA           L +  RE+I   +  DP +I  +  ++ 
Sbjct: 310 GHNLGAGLPRDARFAAGVGMAAALGYACVSASLMLLLREQIAAMYSPDPAVIAIAASLI- 368

Query: 363 YFAASFPFFGIFSAVTNVFASAGH--TKKNLILGIIRLWGLRIPLSYYLGTT 412
            F+A F F      VT   A  G+  T+  +I+ +   WG+ +P+ Y LG T
Sbjct: 369 VFSALFQFSDALQ-VTAAGALRGYQDTRVTMIMTLFAYWGIGLPVGYSLGLT 419


>pir||F69906 conserved hypothetical protein yojI - Bacillus subtilis
           >gi|2634337|emb|CAB13836.1| (Z99114) similar to
           hypothetical proteins [Bacillus subtilis]
           >gi|3169325|gb|AAC17857.1| (AF026147) YojI [Bacillus
           subtilis]
           Length = 452
           
 Score = 89.3 bits (218), Expect = 8e-17
 Identities = 91/439 (20%), Positives = 184/439 (41%), Gaps = 31/439 (7%)

Query: 1   MANIERTREEILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVW 60
           M   +  RE+I      K LL +  P+ I      +    DT    K+  ++L+    + 
Sbjct: 1   MKETQNAREKI------KQLLHILIPIFITQAGLSLITFLDTVMSGKVSPADLAGVA-IG 53

Query: 61  PLLWFMMSLG-SGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVIS 119
             LW  +  G +G ++A   +V+Q +GA + +K          +  +LS+ +  IG    
Sbjct: 54  SSLWTPVYTGLAGILMAVTPIVAQLLGAEKKQKIPFTVLQAVYVAALLSIAVLVIGYAAV 113

Query: 120 PFALRFIKVTPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIIL 179
              L  + +   V+  A  ++  +  G+            + + G T+  + + + ++ +
Sbjct: 114 DLILGRLNLDIHVHQIAKHFLGFLSLGIFPLFVYTVLRSFIDSLGKTRVTMMITLSSLPI 173

Query: 180 NIILDPVFIF----ILDMGVLGAAIATIISEGIGSIIGGYLLFTGK------VGIKISRD 229
           N +L+ VFIF    +  +G +GA +A+ ++     II  +++          + + + + 
Sbjct: 174 NFVLNYVFIFGKFGMPALGGVGAGLASALTYWCICIISFFIIHKNAPFSEYGIFLTMYKF 233

Query: 230 DLRPDVNLYIKTFKIGLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFA 289
             +   NL     KIGLP        +  F  +  ++  + TV  A++       + ++ 
Sbjct: 234 SWKACKNL----LKIGLPIGFAVFFETSIFAAVTLLMSHFHTVTIASHQAAMNFASLLYM 289

Query: 290 FADGISQAMGTMVGQNIGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFIN 349
               +S A+  +VG   GA  +K AR  ++  +       +F     + FRE+I   + +
Sbjct: 290 LPLSVSMALTIVVGFEAGAARFKDARSYSLIGIMMAIGFSLFTAACILLFREQIAGMYTS 349

Query: 350 DPGIIKESEKVVKYFAASFPFFGIFSAVTNVFASA--GHTKKN--LILGIIRLWGLRIPL 405
           DP ++    ++ ++F     FF +  AV      A  G+   N  L    +  W + +P+
Sbjct: 350 DPDVL----RLTQHFLIYALFFQLSDAVAAPIQGALRGYKDVNYTLAAAFVSYWVIGLPV 405

Query: 406 SYYLGT-TLGDSAGVWIGM 423
            Y +GT T   + G WIG+
Sbjct: 406 GYMVGTFTSLGAFGYWIGL 424


>pir||G70172 conserved hypothetical integral membrane protein BB0584 - Lyme
           disease spirochete >gi|2688513|gb|AAB91523.1| (AE001160)
           conserved hypothetical integral membrane protein
           [Borrelia burgdorferi]
           Length = 448
           
 Score = 88.2 bits (215), Expect = 2e-16
 Identities = 108/450 (24%), Positives = 189/450 (42%), Gaps = 35/450 (7%)

Query: 16  IEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSGFVV 75
           I K LL++A P  I   +    +LTD   +A LG  +    G      +F + +  GF +
Sbjct: 16  IYKDLLKIAIPTAIEFFLFNFISLTDNAMVAYLG--DYPVAGVSLANKFFELFVTIGFSM 73

Query: 76  AGF--AMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVY 133
           AG    + ++    G++K            +++ S     I IV   F LR I       
Sbjct: 74  AGAYNIIATRQYNQGDFKSFRNTFFISILTIILFSFPFILISIVNPFFLLRLISNDERAV 133

Query: 134 PYALKYM-IAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIFILD 192
            Y   Y+ IAIF+ V  A+        L+     K  V +++ +++LN + + +FIF+  
Sbjct: 134 YYGAAYLNIAIFSFV-FAIIKGLIANALKVVEIVKFQVYISVFSVLLNFVFNYIFIFVFH 192

Query: 193 MGVLGAAIATIISEGIGSIIGGYLL---FTGKVGIKISRDDLRPDVNLYIKTFKIGLPAS 249
           MGV+GAAIAT +   +  I+  YL+   F     +    DDL  ++  + +  K  +P  
Sbjct: 193 MGVVGAAIATTVIRTLELIV--YLVCTAFNKNSILHFKLDDLNINIKPFAQLIKFFIPIL 250

Query: 250 IGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAE 309
           + +    FG+++L  I     T  +A Y+I+  +   +F        ++  M+G  +   
Sbjct: 251 LNEFAWFFGYLVLTSIFIGIDTHKYAAYSISFSIYFIIFNIIHSFCISLNIMMGYEM-HN 309

Query: 310 NYKRAREVAI--------KAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVV 361
           + K   +VAI         A  T+F++ +F       F    +   I   GII     V 
Sbjct: 310 SKKEIMKVAIYLSKIGLKLAFLTSFVLFIFSFFAPYIFYTLKYSHLI---GIILRYSSVS 366

Query: 362 KYF-AASFPF-FGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLG--TTLGDSA 417
            +F A +F + FG F A      S G   +  +  +       IP+++ L   T L    
Sbjct: 367 AFFMALAFQYLFGFFRA--GASPSFGAIMEGSVTFV-----YTIPIAFVLANYTNLPFEI 419

Query: 418 GVWIGMGLSNVISALIGFAWFLKGSWMRRI 447
            V+I   L + I  ++   +F    W++ +
Sbjct: 420 IVFI-PSLEDAIKLVVSLPYFYSERWIKSV 448


>dbj|BAB07764.1| (AP001520) unknown conserved protein in others [Bacillus
           halodurans]
           Length = 447
           
 Score = 86.6 bits (211), Expect = 5e-16
 Identities = 89/427 (20%), Positives = 183/427 (42%), Gaps = 21/427 (4%)

Query: 19  TLLRLAYPLIINNLVQVMYNLTDTFWLAK-LGRSELSAPGTVWPLLWFMMSLGSGFVVAG 77
           TLL  A P +   L   +Y + D  ++A+ +G + LSA    +P+   ++++        
Sbjct: 15  TLLAYAAPTMALMLFMSIYTMVDGMFIARYVGATALSAVNIFFPIYGLIIAIALMLGTGA 74

Query: 78  FAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKV--TPDVYPY 135
            A++++ IG    ++A      +     +L L++   G+++    L  +    T +++ +
Sbjct: 75  NAIIAKKIGENNEEEAKENFTFIVICGAVLGLVITVFGLLLMEPILLMLGAGATEELFDF 134

Query: 136 ALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIFILDMGV 195
              Y   I    P  +    F      AG     + + ++  + NI+LD VFI +L MG+
Sbjct: 135 TYTYAKIILCTSPFMILQMLFQNFFVTAGKPNLGLTITVVGGVANIVLDYVFIVLLQMGI 194

Query: 196 LGAAIATIISEGIGSIIG-GYLLFTGKVGIKISRDDLRPDVNLYIKTFKIG---LPASIG 251
            GA IAT I   I +  G  Y ++  + G+   +   + D  + + +   G   + +++ 
Sbjct: 195 AGAGIATAIGIFIPAAYGFVYFIYNKESGLHFVKP--KVDGKVLLNSCINGSSEMVSNLA 252

Query: 252 DSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAENY 311
            S  +F F LL  +I   G    A  TI   +   + + + G S  +  ++  N G++N 
Sbjct: 253 SSIVTFAFNLL--MIKHLGVDGVAAITIMLYVMFILSSISMGYSAGVAPIISYNYGSKNS 310

Query: 312 KRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFI-----NDPGIIKESEKVVKYFAA 366
            + + V       + LI+V G++           +FI         +   + + +  F+ 
Sbjct: 311 SQLKRV----FNYSLLIIVIGSVTMYGVSMMFGAYFIQFMAPEGSAVYHIAIEGLNIFSI 366

Query: 367 SFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLGDSAGVWIGMGLS 426
           SF F G     + VF +  + K +  +  +R     +   + L   LG   G+W+ + L+
Sbjct: 367 SFLFMGFNIFSSMVFTAFSNGKISAAISFLRTLVFVLASLWILPAILG-VTGIWLAIPLA 425

Query: 427 NVISALI 433
            ++S ++
Sbjct: 426 EILSVIV 432


>dbj|BAB04579.1| (AP001510) unknown conserved protein [Bacillus halodurans]
           Length = 458
           
 Score = 85.8 bits (209), Expect = 9e-16
 Identities = 91/447 (20%), Positives = 185/447 (41%), Gaps = 42/447 (9%)

Query: 18  KTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLG-SGFVVA 76
           K  L +  P++I  +     N  DT    + G ++L+    +   LW  +  G +G ++A
Sbjct: 12  KLFLVVMMPILITQIGLYAMNFFDTVMSGQAGANDLAGVA-IGSSLWVPVFTGLNGVLLA 70

Query: 77  GFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYPYA 136
              +++Q IGA +      V      L + +S+ +  IG V+    L  + +  +V   A
Sbjct: 71  LTPIIAQSIGAEKRDDVPYVFLQGLYLSIAISIAVILIGAVVLDPILSAMSLEDEVGRIA 130

Query: 137 LKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIFILDMGVL 196
            +Y+I +  G+       T   ++ + G+T+  + + +L++ +NI  + V IF    G L
Sbjct: 131 KEYLIGLAFGIVPLFIYTTIRCLIDSLGETRVTMFITLLSLPINIFFNYVLIF----GKL 186

Query: 197 GAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRP--DVNLYIKTFKI---------- 244
           G      +  G  S I  + +    + + +    +RP  D  L+ K + +          
Sbjct: 187 GFPRLGGVGAGYASAITYWFILAVAIVVVVK---VRPFTDFQLFKKLYHVSLKKWKEILL 243

Query: 245 -GLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVG 303
            GLP        +  F  +  ++ T+ T   A +       +F++     I+  +   VG
Sbjct: 244 LGLPIGFTIFFETSIFAAVTLLMSTFDTATIAAHQAAVNFASFLYMIPLSIAFTLTIAVG 303

Query: 304 QNIGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKY 363
             +GA+  + AR+ +   +    ++ +   ++    R  +   + ND          V +
Sbjct: 304 YEVGAKRVEDARQYSRLGITFALIMGLVAGVIIYVLRAPVASLYTND--------SQVAW 355

Query: 364 FAASFPFFGIFSAVTNVFAS------AGHTKKNL--ILGIIRLWGLRIPLSYYLG--TTL 413
               F  + IF  +++  A+       GH   N+  ++ ++  W + +P  Y L   + L
Sbjct: 356 LIQQFLIYSIFFQLSDALATPIQGVLRGHKDVNVPFVMALVSFWIIGLPTGYLLANFSPL 415

Query: 414 GDSAGVWIGMGLSNVISALIGFAWFLK 440
           G   G WIG+ ++ + S  I  +W LK
Sbjct: 416 G-PYGYWIGL-ITGLASCAIALSWRLK 440


>gb|AAG19201.1| (AE005016) DNA damage-inducible protein; Dip2 [Halobacterium sp.
           NRC-1]
           Length = 489
           
 Score = 83.9 bits (204), Expect = 3e-15
 Identities = 104/450 (23%), Positives = 175/450 (38%), Gaps = 26/450 (5%)

Query: 11  ILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWL-AKLGRSELSAPGTVWPLLWFMMSL 69
           ++S S  +    LA+P I+  + ++  +  D   + A LG + ++  G   P      S+
Sbjct: 36  LISESRARRTAELAWPRILTGIGRMSKSAADVAMVGAALGSAAITGVGYAGPFWGAAFSI 95

Query: 70  GSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVT 129
           G G      A+VSQ   A E   A +   S  +L +  +L +A +        +  +   
Sbjct: 96  GGGLAAGTIALVSQRFSADEIADAGQALRSSAALTVAATLPIAVLFYSHPAALIGLLTDR 155

Query: 130 PDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIF 189
                +   Y+  +  GVP A      +  L  A D  T + +     + NI L+ VFIF
Sbjct: 156 QAEIAFGADYLRVVAFGVPFAGLNLIGSRALIGADDAYTAMVLRGGGALANIGLNGVFIF 215

Query: 190 ILDMGVLGAAIATIISEGI---GSIIG---GYLLFTGKVGIKIS-------RDDLRPDVN 236
            L  GV+GA + T++S  +     ++G   G L   G   + +S       RDD    V 
Sbjct: 216 GLGWGVVGAGLGTVLSNVVVTTAFVVGLSRGRLPAVGAFPMTVSVRGAYWVRDDCWDIVT 275

Query: 237 LYIKTFKIGLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQ 296
                  IGLP    +S  +     L   +  +G    A Y I  R+   M     G   
Sbjct: 276 -------IGLPVVGRNSVWTLARFPLLAFMSLFGQPVAAAYIIVRRVFGIMNTPGWGFGL 328

Query: 297 AMGTMVGQNIGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFI---NDPGI 353
           A  ++VGQ +G      A     +    + ++ V    +  AF  +I   F+   +DP +
Sbjct: 329 AASSLVGQELGQGRESTAAAYGREITLYSVVMYVMFAGVVCAFAGQIVGVFVDSASDPSV 388

Query: 354 IKESEKVVKYFAASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTL 413
                 V    AA  P  GI + V     + G T+       + + G  +PL Y   TT 
Sbjct: 389 PIAVTMVYVAAAAVIP-QGIGATVAGALDATGDTRWPFYSRAVGMLG-ALPLVYLGATTP 446

Query: 414 GDSAGVWIGMGLSNVISALIGFAWFLKGSW 443
               G+++ +     + A++ +  F  G W
Sbjct: 447 LGLYGIYLSLFSETCVPAVVNYLRFRSGKW 476


>gb|AAF21214.1|AC013483_38 (AC013483) putative integral membrane protein [Arabidopsis
           thaliana] >gi|11128377|gb|AAG31183.1|AC074395_4
           (AC074395) MATE efflux family protein, putative
           [Arabidopsis thaliana]
           Length = 526
           
 Score = 82.7 bits (201), Expect = 8e-15
 Identities = 87/356 (24%), Positives = 152/356 (42%), Gaps = 13/356 (3%)

Query: 91  KKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPD--VYPYALKYMIAIFAGVP 148
           K+  R A +   L L+L L+ A   I  S   L  + V P+  +   A KY+     G P
Sbjct: 165 KRTIRTASTAMILGLILGLVQAIFLIFSSKLLLGVMGVKPNSPMLSPAHKYLSIRALGAP 224

Query: 149 VALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIFILDMGVLGAAIATIISEGI 208
             L       + R   DTKTP+   ++  ++NI+LDP+FIF+L +G++GAAIA +IS+  
Sbjct: 225 ALLLSLAMQGIFRGFKDTKTPLFATVVADVINIVLDPIFIFVLRLGIIGAAIAHVISQYF 284

Query: 209 GSIIGGYLLFTGKVG-IKISRDDLRPDVNLYIKTFKIGLPASIGDSTNSFGFVLLNRIIY 267
            ++I  ++    KV  I  +  DL+     + +  K GL         +F   L   +  
Sbjct: 285 MTLI-LFVFLAKKVNLIPPNFGDLQ-----FGRFLKNGLLLLARTIAVTFCQTLAAAMAA 338

Query: 268 TYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAENYKRAREVAIKAMATNFL 327
             GT   A + I  ++        DG++ A   ++  +   ++Y +   VA + +   F 
Sbjct: 339 RLGTTPMAAFQICLQVWLTSSLLNDGLAVAGQAILACSFAEKDYNKVTAVASRVLQMGF- 397

Query: 328 ILVFGTLLFMAFREEI-FRFFINDPGIIKESEKVVKYFAASFPFFGIFSAVTNVFASAGH 386
           +L  G  +F+          F  DP +I      + + AA+ P   +   +  V   A  
Sbjct: 398 VLGLGLSVFVGLGLYFGAGVFSKDPAVIHLMAIGIPFIAATQPINSLAFVLDGVNFGASD 457

Query: 387 TKKNLILGIIRLWGLRIPLSYYLGTTLGDSAGVWIGMGLSNVISALIGFAWFLKGS 442
                   ++ +  + I    Y+  T G   G+WI + +   + A+ G A    G+
Sbjct: 458 FAYT-AYSMVGVAAISIAAVIYMAKTNG-FIGIWIALTIYMALRAITGIARMATGT 511


>gi|8922709 hypothetical protein FLJ10847 [Homo sapiens]
           >gi|7023138|dbj|BAA91852.1| (AK001709) unnamed protein
           product [Homo sapiens]
           Length = 570
           
 Score = 80.8 bits (196), Expect = 3e-14
 Identities = 89/435 (20%), Positives = 180/435 (40%), Gaps = 13/435 (2%)

Query: 18  KTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFM-MSLGSGFVVA 76
           + LL LA P  +  L+  + +   + +   LG+ EL A      ++    +S+G G   A
Sbjct: 36  RALLVLAGPAFLVQLMVFLISFISSVFCGHLGKLELDAVTLAIAVINVTGVSVGFGLSSA 95

Query: 77  GFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYPYA 136
              ++SQ  G+   K    +     +L+L+L         + +   L   +  PDV    
Sbjct: 96  CDTLISQTYGSQNLKHVGVIL-QRSALVLLLCCFPCWALFLNTQHILLLFRQDPDVSRLT 154

Query: 137 LKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIFILDMGVL 196
             Y+      +P           L   G     +   +   ++N + + +F+  L +GV+
Sbjct: 155 QTYVTIFIPALPATFLYMLQVKYLLNQGIVLPQIVTGVAANLVNALANYLFLHQLHLGVI 214

Query: 197 GAAIATIISEGIGSIIGGYLLFTGKVGIKISRDD----LRPDVNLYIKTFKIGLPASIGD 252
           G+A+A +IS+   ++    LLF   +G K+ +          +  +    ++ +P+ +  
Sbjct: 215 GSALANLISQYTLAL----LLFLYILGKKLHQATWGGWSLECLQDWASFLRLAIPSMLML 270

Query: 253 STNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAENYK 312
               + + + + +    G V     +I   L   ++    G S A    VG  +GA + +
Sbjct: 271 CMEWWAYEVGSFLSGILGMVELGAQSIVYELAIIVYMVLAGFSVAASVRVGNALGAGDME 330

Query: 313 RAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYFAASFPFFG 372
           +AR+ +  ++    L  V  ++L ++ ++ +   F  D  II    +VV  +A S  F  
Sbjct: 331 QARKSSTVSLLITVLFAVAFSVLLLSCKDHVGYIFTTDRDIINLVAQVVPIYAVSHLFEA 390

Query: 373 IFSAVTNVFASAGHTKKNLILGIIRLW--GLRIPLSYYLGTTLGDSAGVWIGMGLSNVIS 430
           +      V   +G+ K   I+  I  +  GL I ++    TTLG   G+W G+ +  V  
Sbjct: 391 LACTSGGVLRGSGNQKVGAIVNTIGYYVVGLPIGIALMFATTLG-VMGLWSGIIICTVFQ 449

Query: 431 ALIGFAWFLKGSWMR 445
           A+    + ++ +W +
Sbjct: 450 AVCFLGFIIQLNWKK 464


>pir||E82175 conserved hypothetical protein VC1631 [imported] - Vibrio cholerae
           (group O1 strain N16961) >gi|9656143|gb|AAF94782.1|
           (AE004241) conserved hypothetical protein [Vibrio
           cholerae]
           Length = 458
           
 Score = 80.4 bits (195), Expect = 4e-14
 Identities = 98/458 (21%), Positives = 185/458 (39%), Gaps = 31/458 (6%)

Query: 12  LSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGS 71
           + G   + L+ +A P+ + N++     L D   L +LG +E++A G      +    +  
Sbjct: 11  MRGDFFRRLIAIALPITLQNIMFSSRGLVDVLMLGQLGEAEIAAVGVAARATFVTTIMLV 70

Query: 72  GFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPF-ALRFIKVTP 130
           G    G  + +QY GAG+ K          +L  ++S   A   +++  F   + + +T 
Sbjct: 71  GVTTGGALLTAQYWGAGDRKGVREST----ALTWLVSNFFAFFTVLLFLFFPQQIMSLTT 126

Query: 131 D---VYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVF 187
           D   V     +Y+I     +     + +    LRA          + + I+ N++L+ + 
Sbjct: 127 DSEQVNALGSQYLIITSFTMFAVACVSSMAVGLRAMHKPGVSTFFSGIGIVSNVVLNWIL 186

Query: 188 IF----ILDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLR-----PDVNLY 238
           IF       MG+ GAAIAT++S  I        L+  K  +     D++     P ++ +
Sbjct: 187 IFGKFGFPAMGIQGAAIATVLSGAIEIACLYSYLYGKKHLMAFGWQDIKAVIDWPKISRF 246

Query: 239 IKTFKIGLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAM 298
           ++   + LP +      + G    + I+   G    A  ++   + +   +   G+S A 
Sbjct: 247 LR---LSLPTTFNFLIWAAGLFTYHAIMGQTGVQGLAALSVMTPVESISLSLLIGMSTAA 303

Query: 299 GTMVGQNIGAENYKRAREVAIKAMATNFLI-LVFGTLLFMAFREEIFRFFINDPGIIKES 357
             +VG  +GA+NY+     AI   A + L+ +V    L++     +  F    P   + S
Sbjct: 304 AVLVGNQLGAKNYEAVYYQAIGVTACSVLVGIVVAIGLYLVQIPVLGAFTALTPETRELS 363

Query: 358 EKVVKYFA-----ASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTT 412
           EK +          SFP     +A+  V  + G  K  L   I+  W + IPL+ +    
Sbjct: 364 EKFMLILCLGIVLRSFP----MTAIVGVLRAGGDVKFCLGQDIVAQWCIGIPLAAFAALV 419

Query: 413 LGDSAGVWIGMGLSNVISALIGFAWFLKG-SWMRRIVE 449
           L         + L+  +    G    +K   WM+ ++E
Sbjct: 420 LKVEPEWIYLLFLTEEVVKWFGSLHRMKSKKWMKNLIE 457


>sp|Q55364|Y896_SYNY3 HYPOTHETICAL 49.7 KDA PROTEIN SLR0896 >gi|7449158|pir||S75711
           hypothetical protein slr0896 - Synechocystis sp. (strain
           PCC 6803) >gi|1001206|dbj|BAA10446.1| (D64003)
           hypothetical protein [Synechocystis sp.]
           Length = 461
           
 Score = 78.8 bits (191), Expect = 1e-13
 Identities = 91/443 (20%), Positives = 183/443 (40%), Gaps = 18/443 (4%)

Query: 18  KTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSGFVVAG 77
           +  L+LA PL    + Q      DT  +  LG+  L+A G    +    M  G G +   
Sbjct: 15  REFLKLAVPLAGAQMAQAATGFVDTVMMGWLGQDVLAAGGLATMIFMAFMMTGVGLISGV 74

Query: 78  FAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYPYAL 137
             +V++  GAG+ ++  ++      ++L+LS+    + I      + +          + 
Sbjct: 75  SPLVAEAYGAGQTRRIGQLTRQGLWIVLLLSIP-GMLFITHLNGVMHWSGQADTTIILSD 133

Query: 138 KYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIF----ILDM 193
            Y+  +  G+  A+   T    + A    +  + + I   + NI+ +    F       +
Sbjct: 134 SYLNVMAWGLFPAIAFATLRGCIIALSQARPIMLIVIAATLFNILGNYGLGFGKWGFPAL 193

Query: 194 GVLGAAIATIISEGIGSI-IGGYLLF---TGKVGIKISRDDLRPDVNLYIKTFKIGLPAS 249
           G+ G AIA+I +  I  + +  Y+L+     +  +  S   L+P   +  +   +G P  
Sbjct: 194 GITGLAIASISAHWIMFLSLLVYMLWHKPLHQYSLFDSLHHLKP--RILQQLLWVGGPIG 251

Query: 250 IGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAE 309
           I        ++  +  +   GT   A + + ++    +F     +S A    VGQ  G +
Sbjct: 252 IAAVLEYGLYLTASFFMGALGTPILAAHQVVSQTVLVLFMVPLAMSYAATVRVGQWFGQQ 311

Query: 310 NYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFI--NDPG---IIKESEKVVKYF 364
           ++ + R+ A+ ++    L ++   +  +A+ ++I   ++  NDP     +     ++K  
Sbjct: 312 HWPQIRQAALVSIGLAVLFMLTAGIALLAYPQQIIGLYLDLNDPANGEALNVGISIMKIA 371

Query: 365 AASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLG-TTLGDSAGVWIGM 423
           A      G+      V      T+  ++LG I  WG+ +  SY LG  T    AGVWIG 
Sbjct: 372 AFGLVLDGLQRTANGVLQGLQDTRIPMVLGTIAYWGIGLTASYLLGFYTPLSGAGVWIGT 431

Query: 424 GLSNVISALIGFAWFLKGSWMRR 446
            +  + +A I + W  +   +R+
Sbjct: 432 YI-GLAAASIAYLWRFQKVMVRK 453


>pir||H75559 conserved hypothetical protein - Deinococcus radiodurans  (strain
           R1) >gi|6457769|gb|AAF09695.1|AE001873_5 (AE001873)
           conserved hypothetical protein [Deinococcus radiodurans]
           Length = 451
           
 Score = 75.3 bits (182), Expect = 1e-12
 Identities = 91/440 (20%), Positives = 176/440 (39%), Gaps = 39/440 (8%)

Query: 18  KTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSGFVVAG 77
           + LLRLA P++++        L  T  + +LG  EL+A        + +  +  G +++ 
Sbjct: 16  RALLRLAGPVVVSQFAANALALIATAVIGRLGERELAAAAYANAAYYLVFIMVVGVMLSV 75

Query: 78  FAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYPYAL 137
              V+Q  GAG+ +  +R  G    L L+LS ++  +      +AL F  V P+  P  +
Sbjct: 76  APRVAQAHGAGDARGVARALGGGLRLALLLSAVMLPL-----MWALSF--VLPNFAPAGV 128

Query: 138 K------YMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIF-- 189
                  Y+     G+   L        L   G       V +  ++  +++ P   F  
Sbjct: 129 SRDLVAAYLRVYSLGMLPNLAFIALRGTLEGTGKPGAVTGVALTGVVWALLVAPALAFGW 188

Query: 190 --ILDMGVLGAA-----IATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIKTF 242
             +  +G+ GAA      A I++  +  +    + + G +G     D++R         F
Sbjct: 189 GPLPRLGLAGAAGASASAAWIMAALLWPLARRRVAYAGPLG--PLGDEVR-------ALF 239

Query: 243 KIGLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMV 302
           ++G P  +        F +   ++  +G    A + +T +     F    GI+ A G  V
Sbjct: 240 RLGWPIGLTLGAEGGMFSVTTLLMARFGPEVLAAHNVTMQTITAFFMVPLGIASATGVRV 299

Query: 303 GQNIGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFF--INDP---GIIKES 357
           G   GA    +AR   +  +  +  +++   ++ +A    +F  F  +NDP   G+I  +
Sbjct: 300 GTEAGAGRLAQARRAGLVGLGLSSAVMLTFAVIELAAPRTVFSVFVNVNDPANAGLIAAA 359

Query: 358 EKVVKYFAASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLGDSA 417
              +   A      G+             T+  L++ ++  W + + L   L +  G  A
Sbjct: 360 TGFLSIAALFQLMDGLQVTANGALRGLQDTRVPLLVSLVAYWVVGLGLGSVLSSVAGLGA 419

Query: 418 -GVWIGM--GLSNVISALIG 434
            G+W G+  GL+    +L+G
Sbjct: 420 RGLWFGLTAGLTLAGLSLVG 439


>pir||E82527 multidrug efflux protein XF2686 [imported] - Xylella fastidiosa
           (strain 9a5c) >gi|9107925|gb|AAF85483.1|AE004074_7
           (AE004074) multidrug efflux protein [Xylella fastidiosa]
           Length = 469
           
 Score = 75.3 bits (182), Expect = 1e-12
 Identities = 95/431 (22%), Positives = 172/431 (39%), Gaps = 16/431 (3%)

Query: 14  GSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSGF 73
           GS  +  L LA PL++ ++   +                L+A      LLW  M +  G 
Sbjct: 27  GSEVRPTLLLALPLVLGHVSTGLIGFVLNVIAGHHSTVTLAASTIGTALLWLPMLVPMGT 86

Query: 74  VVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIV---ISPFALRFIKVTP 130
           +++   +VSQ  GA    +  R  G L+   L L++LL  +      + P  L    + P
Sbjct: 87  LISLTVLVSQLHGA----ERERDIGPLFRQALWLAMLLGLVMFTFLSVVPALLPLFGIVP 142

Query: 131 DVYPYALKYMIAIFAG---VPVALTLHTFNFVLRAAGDTKTPVKVNILTII-LNIILDPV 186
           D+ P A K++  +  G    P+   +  F   +     T       +L ++ L+  L   
Sbjct: 143 DIVPGAAKFLHVVRWGSLAFPLYFCMRYFCEGMHCTFPTMLLGFGGLLVLVPLSYALTYG 202

Query: 187 FIFILDMGVLGAAIATIISEGIGSIIGGYLLFTGK--VGIKISRDDLRPDVNLYIKTFKI 244
                + GV G  IAT++   + +++    L+  +    +++      P          I
Sbjct: 203 RFGFSEYGVEGLGIATVMVMWLQAVVFALYLWRSRRFAHLQLFAHLELPCWARIRDLLNI 262

Query: 245 GLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQ 304
           GLP  I        F++   +I  +GT   A + I   +    F    G+++A    +G 
Sbjct: 263 GLPIGISILMEGGLFIVTTLLIGRFGTDEIAAHQIALSVAQLCFMIPMGVAEATTVRIGH 322

Query: 305 NIGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYF 364
            +G  +    R VA    A           + +   + I   + +D  +   + K++  F
Sbjct: 323 AVGRCDLLVMRRVAWAGYAIVIGTQTLSASVLLLGYDVIVAAYTDDLVVASLASKLL-LF 381

Query: 365 AASFPF-FGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTL-GDSAGVWIG 422
           AA F F  G+    + V      T+  ++L +I  WGL +PL   LG  L  +S G+WIG
Sbjct: 382 AAIFQFPDGLQMLSSGVLRGMKDTRVPMLLAMISYWGLGMPLGLGLGFALEWNSRGMWIG 441

Query: 423 MGLSNVISALI 433
           + +    +A++
Sbjct: 442 LIIGLTAAAVL 452


>pir||D81950 probable transmembrane efflux protein NMA1022 [imported] -
           Neisseria meningitidis (group A strain Z2491)
           >gi|7379724|emb|CAB84291.1| (AL162754) putative
           transmembrane efflux protein [Neisseria meningitidis
           Z2491]
           Length = 459
           
 Score = 74.9 bits (181), Expect = 2e-12
 Identities = 85/442 (19%), Positives = 177/442 (39%), Gaps = 32/442 (7%)

Query: 18  KTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSGFVVAG 77
           + L  LA P+++  + QV     DT      G+ +L+A          +     G + A 
Sbjct: 18  RLLTALALPMLLAQVAQVGIGFVDTVMAGGAGKEDLAAVALGSSAFATVYITFMGIMAAL 77

Query: 78  FAMVSQYIGAGEYKKASRVA--GSLYSLLL-MLSLLLAGIGIVISPFALRFIKVTPDVYP 134
             M++Q  GAG+  +       G  + L L +  ++L  +   I+PF   ++ ++  V  
Sbjct: 78  NPMIAQLYGAGKTDEVGETGRQGIWFGLFLGVFGMVL--MWAAITPFR-NWLTLSDYVEG 134

Query: 135 YALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIF-ILDM 193
              +YM+     +P A+     +    +    +  + V+    +LN+ L+ +F++    M
Sbjct: 135 TMAQYMLFTSLAMPAAMVHRALHAYASSLNRPRLIMLVSFAAFVLNVPLNYIFVYGKFGM 194

Query: 194 GVLGAAIATIISEGIGSIIGGYLLFTG-KVGIKISRDDL-----------RPDVNLYIKT 241
             LG A       G G        F+   + I I++++            +PD  ++ + 
Sbjct: 195 PALGGA-------GCGLATMAVFWFSALALWIYIAKENFFRPFGLTAKFGKPDWAVFKQI 247

Query: 242 FKIGLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTM 301
           +KIG P  +     +  F  +  +I  +G    A   +   L+  ++     +  A    
Sbjct: 248 WKIGAPIGLSYFLEASAFSFIVFLIAPFGEDYVAAQQVGISLSGILYMIPQSVGSAGTVR 307

Query: 302 VGQNIGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVV 361
           +G ++G   + RAR ++  ++ + +++ V   L  + FR  +   + NDP ++  +  V+
Sbjct: 308 IGFSLGRREFSRARYISGVSLVSGWMLAVITVLSLVLFRSPLVSMYNNDPAVLSIAATVL 367

Query: 362 KYFAASFPFFGIFSAVTNVFASAGH--TKKNLILGIIRLWGLRIPLSYYLGTTLGDSA-G 418
            +     P    F+     +A  G+  TK  + +     WG  +   Y L         G
Sbjct: 368 LFAGLFQP--ADFTQCIASYALRGYKVTKVPMFIHAAAFWGCGLLPGYLLAYRFDMGIYG 425

Query: 419 VWIGMGLSNVISALIGFAWFLK 440
            W  + ++++  A I   W L+
Sbjct: 426 FWTAL-IASLTIAAIALVWCLE 446


>gb|AAG27731.1|AF312031_1 (AF312031) multi-drug efflux transporter [Burkholderia
           vietnamiensis]
           Length = 462
           
 Score = 74.9 bits (181), Expect = 2e-12
 Identities = 100/438 (22%), Positives = 179/438 (40%), Gaps = 24/438 (5%)

Query: 22  RLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSGFVVAGFAMV 81
           RLA PL I  L Q+  ++TDT  L  LG   L+A G      + ++++  G + +    V
Sbjct: 25  RLAAPLAIAQLSQMAMSVTDTVLLGSLGPDSLAAGGLGANFFFVIVTVLQGVLSSVSVSV 84

Query: 82  SQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYPYALKYM- 140
           +   GA    +   +  + + L ++L+ + A + + +S   L      P +  +  +Y  
Sbjct: 85  AHARGAQAEHRVPHIYWTGFVLSVLLA-IPAVVALSLSEPLLLMFHEPPTLAQHVGEYTG 143

Query: 141 IAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIF----ILDMGVL 196
           I  FA +   + +      L A G  +  + V+I  I +N +L+   I     +  +G L
Sbjct: 144 ILRFAALGSLIGVGLMRAFLPAIGAARRLLWVSIGGIGVNAVLNYGLIHGAYGLPRLGFL 203

Query: 197 GAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIKTFKIGLPASIGDSTNS 256
           G+A+AT I+  + +    +LL  G+   +      RP + +  +   IG P +I     S
Sbjct: 204 GSAVATTITIWLTAFALIWLLH-GRARFRHFVSAARPKLPMMGELIGIGWPVAITYGVES 262

Query: 257 FGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAENYKRARE 316
             F+     +   G  A A + I   + +  F     I QA    VG  IGA +   AR 
Sbjct: 263 TLFLATGLTVGVLGATALAAHQIALNVASVAFMVPLAIGQAANVRVGYWIGAGDPVAARH 322

Query: 317 VAIKAMATNFLILVFGTLLFMAFREEIFRFF--INDPGIIKESEKVVKYFAASFPFFGIF 374
               A+      +    L+ +     I   +  ++DP     +   V   A+      +F
Sbjct: 323 AGFVALGLGVAFMSLSGLVLILAPHAIVGLYLHLDDPA----NAATVSLAASLLGIAAVF 378

Query: 375 SAV-------TNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTTLGDSA-GVWIGM--G 424
             V       +        T+  ++      WG+  P  Y+L    G  A G+W G+  G
Sbjct: 379 QIVDGMQTVGSGALRGLRDTRIPMLAATFGYWGIGFPTGYWLAFHAGLGARGLWWGLAAG 438

Query: 425 LSNVISALIGFAWFLKGS 442
           L++V + L+ + + LK S
Sbjct: 439 LASV-AVLMAWRFHLKTS 455


>pir||F70172 conserved hypothetical integral membrane protein BB0583 - Lyme
           disease spirochete >gi|2688514|gb|AAB91524.1| (AE001160)
           conserved hypothetical integral membrane protein
           [Borrelia burgdorferi]
           Length = 449
           
 Score = 74.5 bits (180), Expect = 2e-12
 Identities = 95/444 (21%), Positives = 179/444 (39%), Gaps = 23/444 (5%)

Query: 16  IEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSGFVV 75
           I K L  +A P    +L+  M    D F ++ LG   ++       + +    +  G   
Sbjct: 11  IIKELFVIAIPTAFESLLFQMVTFFDNFMISYLGSFHVTGVSLANRVTFLFFIIVFGLGT 70

Query: 76  AGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYPY 135
           A  A VSQ I     KK  +V  S   +LL+ +     IGI+   F+  F +    ++  
Sbjct: 71  ALSAYVSQAIAK---KKFLQVRQSFAYILLIGTT----IGIIFFIFSFLFPRNIIKLFTA 123

Query: 136 ---ALKYMIAIFAGVPVALTLHTFNFV----LRAAGDTKTPVKVNILTIILNIILDPVFI 188
              +L +       + ++  L  ++F+     ++A + K P+ V  + +++NI+ + + I
Sbjct: 124 NQDSLNFGSEYLKIISLSYVLMAYSFLSAMGFKSAKEVKIPLYVTSIVVLINIVFNYILI 183

Query: 189 FILDMGVLGAAIATIISEGIGSIIGG-YLLFTGKVGIKISRDDLRPDVNLYIKTFKIGLP 247
           F   MG+ GAA AT+++  +  +    Y L +     +I   D      +     K+ +P
Sbjct: 184 FGFSMGIKGAAYATVLARIVEFVFYFLYSLISSNSYYRIKFGDFFAPKVVTRANLKLIIP 243

Query: 248 ASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIG 307
               +        +L+      G++ +A++ + + L +  F    G+  A G ++G ++ 
Sbjct: 244 VLSHEIFWVLSITILHAFYARVGSIEYASFAVASNLFDICFVLLHGMGLATGVVIG-HLM 302

Query: 308 AENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYFAAS 367
             + K  R V        FL+ +F  +L +      F  +I       E   V  Y  AS
Sbjct: 303 IYDKKHVRSVGFFLSFLGFLLGIFVVILLIGISS--FAPYIFSKLDSPELVSVFIYVFAS 360

Query: 368 FPFFGIFSA--VTNVFASAGHTKKNLIL--GIIRLWGLRIPLSYYLGTTLGDSAGVWIGM 423
              F  F+A  +  VF ++G       +  G+I  + L +       T L     V+I +
Sbjct: 361 IVIFKAFTAQVLVGVFRASGIPNVCFFIESGVIVFYTLPVAYLLVFYTNLSLPIVVFI-V 419

Query: 424 GLSNVISALIGFAWFLKGSWMRRI 447
            L  +I  +     F    W+R I
Sbjct: 420 NLEEIIKNIFIIIEFFHDDWIREI 443


>pir||C81156 conserved hypothetical protein NMB0812 [imported] - Neisseria
           meningitidis (group B strain MD58)
           >gi|7226046|gb|AAF41225.1| (AE002434) conserved
           hypothetical protein [Neisseria meningitidis MC58]
           Length = 459
           
 Score = 74.5 bits (180), Expect = 2e-12
 Identities = 85/442 (19%), Positives = 176/442 (39%), Gaps = 32/442 (7%)

Query: 18  KTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSGFVVAG 77
           + L  LA P+++  + QV     DT      G+ +L+A          +     G + A 
Sbjct: 18  RLLTTLALPMLLAQVAQVGIGFVDTVMAGGAGKEDLAAVALGSSAFATVYITFMGIMAAL 77

Query: 78  FAMVSQYIGAGEYKKASRVA--GSLYSLLL-MLSLLLAGIGIVISPFALRFIKVTPDVYP 134
             M++Q  GAG+  +       G  + L L +  ++L  +   I+PF   ++ ++  V  
Sbjct: 78  NPMIAQLYGAGKTDEVGETGRQGIWFGLFLGVFGMVL--MWAAITPFR-NWLTLSDYVEG 134

Query: 135 YALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIF-ILDM 193
              +YM+     +P A+     +    +    +  + V+    +LN+ L+ +F++    M
Sbjct: 135 TMAQYMLFTSLAMPAAMVHRALHAYTSSLNRPRLIMLVSFAAFVLNVPLNYIFVYGKFGM 194

Query: 194 GVLGAAIATIISEGIGSIIGGYLLFTG-KVGIKISRDDL-----------RPDVNLYIKT 241
             LG A       G G        F+   + I I++++            +PD  ++ + 
Sbjct: 195 PALGGA-------GCGLATMAVFWFSALALWIYIAKENFFRPFGLTAKFGKPDWAVFKQI 247

Query: 242 FKIGLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTM 301
           +KIG P  +     +  F  +  +I  +G    A   +   L+  ++     +  A    
Sbjct: 248 WKIGAPIGLSYFLEASAFSFIVFLIAPFGEDYVAAQQVGISLSGILYMIPQSVGSAGTVR 307

Query: 302 VGQNIGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVV 361
           +G ++G   + RAR ++  ++   +++ V   L  + FR  +   + NDP ++  +  V+
Sbjct: 308 IGFSLGRREFSRARYISGVSLVLGWMLAVITVLSLVLFRSPLVSMYNNDPAVLSIAATVL 367

Query: 362 KYFAASFPFFGIFSAVTNVFASAGH--TKKNLILGIIRLWGLRIPLSYYLGTTLGDSA-G 418
            +     P    F+     +A  G+  TK  + +     WG  +   Y L         G
Sbjct: 368 LFAGLFQP--ADFTQCIASYALRGYKVTKVPMFIHAAAFWGCGLLPGYLLAYRFNMGIYG 425

Query: 419 VWIGMGLSNVISALIGFAWFLK 440
            W  + ++++  A I   W L+
Sbjct: 426 FWTAL-IASLTIAAIALVWCLE 446


>pir||T02512 hypothetical protein T19C21.18 - Arabidopsis thaliana
           >gi|3395439|gb|AAC28771.1| (AC004683) hypothetical
           protein [Arabidopsis thaliana]
           Length = 539
           
 Score = 73.7 bits (178), Expect = 4e-12
 Identities = 103/452 (22%), Positives = 183/452 (39%), Gaps = 52/452 (11%)

Query: 14  GSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPG---TVWPLLWFMMSLG 70
           G I   ++ +A P  +      + +L DT ++  +G +EL+A G   +V+ L+  + ++ 
Sbjct: 74  GKIGMEIMSIALPAALALAADPITSLVDTAFVGHIGSAELAAVGVSVSVFNLVSKLFNVP 133

Query: 71  SGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVI-------SPFAL 123
              V   F    Q I A +   +   +  +   +    +L AG+GI         S F +
Sbjct: 134 LLNVTTSFVAEEQAIAAKDDNDSIETSKKVLPSVSTSLVLAAGVGIAEAIALSLGSDFLM 193

Query: 124 RFIKV---TPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILN 180
             + +   +P   P      +  +   P+ + L       R   DT TP+   +   +LN
Sbjct: 194 DVMAIPFDSPMRIPAEQFLRLRAYGAPPIVVALAAQG-AFRGFKDTTTPLYAVVAGNVLN 252

Query: 181 IILDPVFIFILDMGVLGAAIATIISEGIGSIIGGYLLFTGKV----GIKISRDDLRPDVN 236
            +LDP+ IF+L  G+ GAA AT+ISE + + I  + L    V     IK+ R       N
Sbjct: 253 AVLDPILIFVLGFGISGAAAATVISEYLIAFILLWKLNENVVLLSPQIKVGR------AN 306

Query: 237 LYIKTFKIGLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQ 296
            Y+K+  + +  ++        F L   +    G    A + I   +   +    D ++ 
Sbjct: 307 QYLKSGGLLIGRTV---ALLVPFTLATSLAAQNGPTQMAGHQIVLEIWLAVSLLTDALAI 363

Query: 297 AMGTMVGQNIGAENYKRAREVAIKAMATNFLILVFGT----LLFMAFREEIFRFFINDPG 352
           A  +++        YK+AREV    +      L  GT    +LF+ F E     F  D  
Sbjct: 364 AAQSLLATTYSQGEYKQAREVLFGVLQVG---LATGTGLAAVLFITF-EPFSSLFTTDSE 419

Query: 353 IIKESEKVVKYFAAS-------FPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPL 405
           ++K +     + A S       F   G++  V++ F  A ++   +I+G I        L
Sbjct: 420 VLKIALSGTLFVAGSQPVNALAFVLDGLYYGVSD-FGFAAYSM--VIVGFIS------SL 470

Query: 406 SYYLGTTLGDSAGVWIGMGLSNVISALIGFAW 437
              +       AG+W G+ L   +  + G AW
Sbjct: 471 FMLVAAPTFGLAGIWTGLFLFMALRLVAG-AW 501


>pir||A82984 hypothetical protein PA5294 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9951609|gb|AAG08679.1|AE004942_2
           (AE004942) hypothetical protein [Pseudomonas aeruginosa]
           Length = 488
           
 Score = 73.7 bits (178), Expect = 4e-12
 Identities = 103/438 (23%), Positives = 175/438 (39%), Gaps = 22/438 (5%)

Query: 18  KTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSLGSGFVVAG 77
           K +LRLA PLI   L  V    TDT  + KLG   L+A G       F+ +   G V A 
Sbjct: 10  KAILRLAGPLIAAQLAYVAMVFTDTVMMGKLGPDALAAGGLGAVSYAFVSTFCVGVVAAV 69

Query: 78  FAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYPYAL 137
             +V+   G  +   A+  A S   +   L+L    +   + P  L F +  P     A+
Sbjct: 70  GNLVAIRHGCDDAAGAAAAARSGLWVGAALALAAGLLLWNLRPLLLVFGQ-APQTVDGAM 128

Query: 138 KYMIAIFAGVP---VALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIFIL--- 191
           +++ ++   +P     + L  F   +  AG     + +++L  + N+ L+  FI  L   
Sbjct: 129 QFLHSLTFALPGYMAFMVLRGFTSAIDRAGPV---MAISVLGALANLALNYSFIEGLFGL 185

Query: 192 -DMGVLGAAIAT-IISEGIGSIIGGYL-LFTGKVGIKISRDDLRPDVNLYIKTFKIGLPA 248
             +G+ G  + T ++   +  ++  Y+ L        + R   RP   +  +  ++GLP 
Sbjct: 186 PRLGLAGIGLVTALVMNCMPLLLALYIRLQPAYAEYSLLRGLGRPQRAMVEEILRLGLPI 245

Query: 249 SIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGA 308
               +  S  F +    +   G  A A + I  +     F    G+S A    +GQ+ GA
Sbjct: 246 GGTYAVESGMFTVATLCMGIIGDHALAAHQIAIQAVYVAFMVPVGLSYATTYRIGQHFGA 305

Query: 309 ENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFIN-DPGIIKESEKVVKYFAAS 367
                AR      +    L ++    LF    E I   F++ D    +E   +     A 
Sbjct: 306 GRLLEARRAGRVGIGFGALCMLLFAGLFWWMPEAIIGLFLDRDAPANREVAAMAVSLLAI 365

Query: 368 FPFFGIFSAVTNVFASA----GHTKKNLILGIIRLWGLRIPLSYYLGTTLG-DSAGVWIG 422
             +F +F    NV   A       +   ++G+   W + +PL+  L    G  +AGVW G
Sbjct: 366 AAWFELFDGTQNVAMGAIRGLKDARTTFLVGLACYWLVGVPLACLLAFAAGWGAAGVWWG 425

Query: 423 M--GLS-NVISALIGFAW 437
           +  GL+   I   + F W
Sbjct: 426 LAGGLACAAIGLTLAFEW 443


>pir||T50435 conserved hypothetical protein SPCC4B3.13 [imported] - fission
           yeast (Schizosaccharomyces pombe)
           >gi|6434021|emb|CAB60687.1| (AL132870) conserved
           hypothetical protein [Schizosaccharomyces pombe]
           Length = 539
           
 Score = 73.4 bits (177), Expect = 5e-12
 Identities = 92/428 (21%), Positives = 175/428 (40%), Gaps = 30/428 (7%)

Query: 20  LLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPG-TVWPLLWFMMSLGSGFVVAGF 78
           L++ A P+++ +L+Q    +T  F L  LG++EL+A   +         ++  G V A  
Sbjct: 100 LIKFATPVVLTSLLQYGEVVTTVFSLGHLGKTELAAASLSNMTATITAFAIYQGIVSALD 159

Query: 79  AMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYPYALK 138
            + +Q  G+G Y+        + ++LL++   +  I   I    L F++  P    +A K
Sbjct: 160 TVGTQSFGSGNYEMVGLHLQRILAILLLIQFPIFLIWWKIEGILL-FLRQDPLTCMFAAK 218

Query: 139 YMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIFI--LDMGVL 196
           YM  +    P           L+  G       +  + + +NI L+ +F++   +  G L
Sbjct: 219 YMRVMMLASPAYALFEALKRFLQVQGIFHPVTYILAIVVPINIFLNYLFVWSPWVGFGFL 278

Query: 197 GAAIATIISEGIGSIIGGYLLFTGKVGIK-----ISRDDLRPDVNLYIKTFKIGLPASIG 251
           GA +A  ++  + S     +++  KV  +      SR+ L+     +    ++ +P  I 
Sbjct: 279 GAPVAVALT--LWSACAVLIIYIMKVNGRQAWGGFSREALKN----WGPLCRLAVPGVIM 332

Query: 252 DSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAENY 311
             +  + F L+       GT   A+ ++ +  +   +  A G++ A  T VG  IGA N 
Sbjct: 333 ICSEYWAFELVTFASGVLGTTELASMSVLSTTSTLSYNLAFGVAAAAATRVGNLIGAGNT 392

Query: 312 KRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYFAASFPFF 371
           K A+     ++     I V   ++    R      F +D       + VV   A   P  
Sbjct: 393 KLAKLATHVSINLGAAIGVIIAVILFLTRNTWTYIFTSD-------KDVVALVATIIPLV 445

Query: 372 GIFSAVTNVFASAGHTKKNL-------ILGIIRLWGLRIPLSYYLGTTLG-DSAGVWIGM 423
            + +   N    AG   +         ++  I  + L +P++  L   L     G+WIG+
Sbjct: 446 ALINIADNTQCVAGGLLRGQGRQRIGGVVNFIAYYLLGLPVAIILCFKLDWGLYGLWIGI 505

Query: 424 GLSNVISA 431
           G + +I A
Sbjct: 506 GAAILIIA 513


>pir||G82364 DNA-damage-inducible protein F VC0090 [imported] - Vibrio cholerae
           (group O1 strain N16961) >gi|9654488|gb|AAF93268.1|
           (AE004100) DNA-damage-inducible protein F [Vibrio
           cholerae]
           Length = 454
           
 Score = 71.4 bits (172), Expect = 2e-11
 Identities = 81/373 (21%), Positives = 158/373 (41%), Gaps = 39/373 (10%)

Query: 15  SIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFM--MSLGSG 72
           ++ + +L +A P++++N+   +  L D    A +G  E +         W++  ++LGS 
Sbjct: 15  NVHRQVLAIALPMVLSNITVPLLGLVDA---AVIGHLEHA---------WYLGGVALGST 62

Query: 73  FVVAGF-----------AMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPF 121
            +   F            + +Q  GA   ++ +RV      + L L+ L       ++  
Sbjct: 63  MISVTFWLLGFLRMSTTGLTAQAHGAQNSQQLARVLLQGSVIALGLAALFLLFHRPVAEL 122

Query: 122 ALRFIKVTPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNI 181
              F   + +V  YA  Y        P AL        L    + + P+ + I+T + NI
Sbjct: 123 IFHFSDASSEVKTYAEAYFYIRAWSAPAALLNFVLLGWLLGTQNARAPMWMVIITNLTNI 182

Query: 182 ILDPVFIFILDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIKT 241
           +LD + +  L + V GAAIA++I++  G + G  LL  G+      R    P    +I +
Sbjct: 183 VLDLLLVLGLGLKVEGAAIASVIADYAGLLFG--LLCVGRYW----RQHQLPAPFSFIPS 236

Query: 242 FKIGLPASIGDSTNSFGFVLLNRIIYTYGTVAFAT-----YTITNRLTNFMFAFA---DG 293
               L   +  + + F   L  + ++++ T   A            L +F+   +   DG
Sbjct: 237 LTKELSRLVALNRDIFLRSLCLQAVFSFMTFQGAALGDDIVAANAVLMSFLMMISYGMDG 296

Query: 294 ISQAMGTMVGQNIGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGI 353
            + AM  MVG+ IGA++ ++ R   I +     +I +  +L+F+ F  ++ +   N P +
Sbjct: 297 FAYAMEAMVGKAIGAKDDRQLRTAMISSTFWATMICLLLSLIFLGFGSDLIQMITNIPSV 356

Query: 354 IKESEKVVKYFAA 366
              +E  + +  A
Sbjct: 357 QATAEHYLPWLVA 369


>pir||T08969 hypothetical protein F19B15.170 - Arabidopsis thaliana
           >gi|4972060|emb|CAB43928.1| (AL078470) putative protein
           [Arabidopsis thaliana] >gi|7269812|emb|CAB79672.1|
           (AL161574) putative protein [Arabidopsis thaliana]
           Length = 532
           
 Score = 71.0 bits (171), Expect = 3e-11
 Identities = 84/430 (19%), Positives = 168/430 (38%), Gaps = 34/430 (7%)

Query: 18  KTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFM-MSLGSGFVVA 76
           K+L  LA+P+ +  LV  + +    F+L +LG  EL+A             S+ SG  + 
Sbjct: 58  KSLFTLAFPIAVTALVLYLRSAVSMFFLGQLGDLELAAGSLAIAFANITGYSVLSGLALG 117

Query: 77  GFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISPFALRFIKVTPDVYPYA 136
              + SQ  GA  +K  S         LL+  + ++ +   +   ++ ++   PD+   A
Sbjct: 118 MEPLCSQAFGAHRFKLLSLTLHRTVVFLLVCCVPISVLWFNVGKISV-YLHQDPDIAKLA 176

Query: 137 LKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIFILDMGVL 196
             Y+I     +     LH     LRA G        ++   + ++  +   +  L +G+ 
Sbjct: 177 QTYLIFSLPDLLTNTLLHPIRIYLRAQGIIHPVTLASLSGAVFHLPANLFLVSYLRLGLT 236

Query: 197 GAAIATIISEGIGSIIGGYLLFTGKVGIKISR--DDLRPDVNLYIKTFKIGLPASIGDST 254
           G A+A+ I+     ++   + +    G+      D  R     +    ++  P+ +    
Sbjct: 237 GVAVASSITNIF--VVAFLVCYVWASGLHAPTWTDPTRDCFRGWAPLLRLAGPSCVSVCL 294

Query: 255 NSFGF----VLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVGQNIGAEN 310
             + +    VL   ++    TVA     I  + T+F++ F   +S A+ T VG  +GA  
Sbjct: 295 EWWWYEIMIVLCGLLVNPRSTVAAMGVLI--QTTSFLYVFPSSLSFAVSTRVGNELGANR 352

Query: 311 YKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKYFAASFPF 370
            K A+  A  A+    +  +       + R    R F  D       +++++  AA+ P 
Sbjct: 353 PKTAKLTATVAIVFAAVTGIIAAAFAYSVRNAWGRIFTGD-------KEILQLTAAALPI 405

Query: 371 FGIFSAVTNVFASAGHTKKNLILGIIR-------LWGLRIPLSYYLGTTLGDSAGVWIGM 423
            G+           G+  + +  G++R          + +   Y +G  +    G W G+
Sbjct: 406 LGL--------CEIGNCPQTVGCGVVRGTARPSTAANVNLGAFYLVGMPVAVGLGFWAGI 457

Query: 424 GLSNVISALI 433
           G + +   L+
Sbjct: 458 GFNGLWVGLL 467


>sp|P37340|YDHE_ECOLI HYPOTHETICAL 49.4 KDA PROTEIN IN RIBC-PYKF INTERGENIC REGION
           >gi|1742737|dbj|BAA15430.1| (D90809) ORF_ID:o319#7;
           similar to [SwissProt Accession Number P37340]
           [Escherichia coli] >gi|1742747|dbj|BAA15439.1| (D90810)
           ORF_ID:o319#7; similar to [SwissProt Accession Number
           P37340] [Escherichia coli]
           Length = 457
           
 Score = 70.2 bits (169), Expect = 4e-11
 Identities = 82/436 (18%), Positives = 177/436 (39%), Gaps = 29/436 (6%)

Query: 18  KTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVWPLLWFMMSL-GSGFVVA 76
           + LL LA P+I+  + Q      DT        ++++A   +   +W    L G G ++A
Sbjct: 9   RLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVA-IGTSIWLPAILFGHGLLLA 67

Query: 77  GFAMVSQYIGAGEYKKASRVA------GSLYSLLLMLSLLLAGIGIVISPFALRFIK-VT 129
              +++Q  G+G  ++ +             S+L+ML L  AG       + +R ++ + 
Sbjct: 68  LTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAG-------YIIRSMENID 120

Query: 130 PDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNIILDPVFIF 189
           P +   A+ Y+ A+  G P  L              TK  + +  + +++NI ++ +FI+
Sbjct: 121 PALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIY 180

Query: 190 ----ILDMGVLGAAIATIISEGIG--SIIGGYLLFTGKVGIKISRDDLRPDVNLYIKTFK 243
               + ++G +G  +AT     +   +++           I+  +   +PD  +  +  +
Sbjct: 181 GHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQ 240

Query: 244 IGLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGTMVG 303
           +GLP ++        F ++  ++   G V  A + I    ++ MF     ++ A+   VG
Sbjct: 241 LGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVG 300

Query: 304 QNIGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKVVKY 363
             +G  +   A+  A   +     +     +  ++ RE+I   + ++P ++  +  ++  
Sbjct: 301 YRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLL 360

Query: 364 FAASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLGTT------LGDSA 417
            A       I    + +      T+    +     W L +P  Y L  T      +G  A
Sbjct: 361 AAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMG-PA 419

Query: 418 GVWIGMGLSNVISALI 433
           G WIG  +    +A++
Sbjct: 420 GFWIGFIIGLTSAAIM 435


>gi|11428103 hypothetical protein FLJ10847 [Homo sapiens]
           Length = 582
           
 Score = 69.1 bits (166), Expect = 1e-10
 Identities = 67/329 (20%), Positives = 137/329 (41%), Gaps = 11/329 (3%)

Query: 123 LRFIKVTPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILNII 182
           L   +  PDV      Y+      +P           L   G     +   +   ++N +
Sbjct: 256 LLLFRQDPDVSRLTQTYVTIFIPALPATFLYMLQVKYLLNQGIVLPQIVTGVAANLVNAL 315

Query: 183 LDPVFIFILDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDD----LRPDVNLY 238
            + +F+  L +GV+G+A+A +IS+   ++    LLF   +G K+ +          +  +
Sbjct: 316 ANYLFLHQLHLGVIGSALANLISQYTLAL----LLFLYILGKKLHQATWGGWSLECLQDW 371

Query: 239 IKTFKIGLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAM 298
               ++ +P+ +      + + + + +    G V     +I   L   ++    G S A 
Sbjct: 372 ASFLRLAIPSMLMLCMEWWAYEVGSFLSGILGMVELGAQSIVYELAIIVYMVPAGFSVAA 431

Query: 299 GTMVGQNIGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESE 358
              VG  +GA + ++AR+ +  ++    L  V  ++L ++ ++ +   F  D  II    
Sbjct: 432 SVRVGNALGAGDMEQARKSSTVSLLITVLFAVAFSVLLLSCKDHVGYIFTTDRDIINLVA 491

Query: 359 KVVKYFAASFPFFGIFSAVTNVFASAGHTKKNLILGIIRLW--GLRIPLSYYLGTTLGDS 416
           +VV  +A S  F  +      V   +G+ K   I+  I  +  GL I ++    TTLG  
Sbjct: 492 QVVPIYAVSHLFEALACTSGGVLRGSGNQKVGAIVNTIGYYVVGLPIGIALMFATTLG-V 550

Query: 417 AGVWIGMGLSNVISALIGFAWFLKGSWMR 445
            G+W G+ +  V  A+    + ++ +W +
Sbjct: 551 MGLWSGIIICTVFQAVCFLGFIIQLNWKK 579


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.328    0.144    0.424 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 155185865
Number of Sequences: 2977
Number of extensions: 6317429
Number of successful extensions: 20597
Number of sequences better than 1.0e-10: 64
Number of HSP's better than  0.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 47
Number of HSP's that attempted gapping in prelim test: 20408
Number of HSP's gapped (non-prelim): 74
length of query: 449
length of database: 189,106,746
effective HSP length: 54
effective length of query: 395
effective length of database: 156,788,448
effective search space: 61931436960
effective search space used: 61931436960
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.7 bits)
S2: 166 (69.1 bits)