BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1439 (PAB1439) DE:dinF related
         (468 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||B75053 dinf related PAB1439 - Pyrococcus abyssi (strain Ors...   913  0.0
pir||C71172 hypothetical protein PH0575 - Pyrococcus horikoshii ...   790  0.0
pir||C75053 DNA damage-inducible protein. PAB1438 - Pyrococcus a...   526  e-148
pir||E71172 probable damage-inducible protein - Pyrococcus horik...   517  e-145
gb|AAG19206.1| (AE005017) Vng0727c [Halobacterium sp. NRC-1]          238  1e-61
pir||E72471 probable DNA-damage-inducible protein APE2414 - Aero...   227  3e-58
pir||H70158 conserved hypothetical integral membrane protein BB0...   214  2e-54
dbj|BAB04605.1| (AP001510) unknown conserved protein [Bacillus h...   192  7e-48
sp|P54181|YPNP_BACSU HYPOTHETICAL 48.5 KD PROTEIN IN ILVA 3'REGI...   178  1e-43
pir||H72331 conserved hypothetical protein - Thermotoga maritima...   175  1e-42
dbj|BAB05882.1| (AP001514) unknown conserved protein in others [...   173  5e-42
pir||A75151 damage-inducible protein PAB0243 - Pyrococcus abyssi...   170  3e-41
pir||G71191 probable DNA damage-inducible protein - Pyrococcus h...   170  3e-41
pir||G72220 conserved hypothetical protein - Thermotoga maritima...   162  8e-39
pir||A82049 conserved hypothetical protein VC2671 [imported] - V...   162  1e-38
sp|Q58119|Y709_METJA HYPOTHETICAL PROTEIN MJ0709 >gi|2128027|pir...   150  2e-35
pir||A69905 conserved hypothetical protein yoeA - Bacillus subti...   147  3e-34
gb|AAG20342.1| (AE005107) DNA damage-inducible protein; DinF [Ha...   146  5e-34
gi|11499066 conserved hypothetical protein [Archaeoglobus fulgid...   145  1e-33
emb|CAA84073.1| (Z34303) DinF protein [Streptococcus pneumoniae]      143  4e-33
pir||C69140 conserved hypothetical protein MTH314 - Methanobacte...   133  4e-30
dbj|BAB06655.1| (AP001517) unknown conserved protein [Bacillus h...   132  8e-30
pir||JC4561 DNA damage-inducible protein homolog - Pyrococcus sp...   129  7e-29
pir||H69837 conserved hypothetical protein yisQ - Bacillus subti...   126  5e-28
pir||G82392 conserved hypothetical protein VCA0989 [imported] - ...   125  8e-28
pir||E82296 conserved hypothetical protein VC0650 [imported] - V...   116  4e-25
gb|AAG20494.1| (AE005121) DNA damage-inducible protein; Dip1 [Ha...   116  5e-25
pir||G64614 conserved hypothetical integral membrane protein HP0...   113  4e-24
pir||E70312 conserved hypothetical protein aq_128 - Aquifex aeol...   112  8e-24
pir||H71898 hypothetical protein jhp0696 - Helicobacter pylori (...   110  3e-23
pir||G70172 conserved hypothetical integral membrane protein BB0...   109  9e-23
sp|P45272|YDHE_HAEIN HYPOTHETICAL PROTEIN HI1612 >gi|1074865|pir...   106  4e-22
pir||H64667 conserved hypothetical integral membrane protein HP1...   104  3e-21
dbj|BAA15804.1| (D90837) ORF_ID:o347#5~similar to [SwissProt Acc...   101  2e-20
sp|P76352|YEEO_ECOLI HYPOTHETICAL 60.1 KDA PROTEIN IN AMN-CBL IN...   101  2e-20
gb|AAG10466.1|AF279106_28 (AF279106) predicted cation efflux pum...   101  2e-20
pir||A71849 hypothetical protein jhp1110 - Helicobacter pylori (...   101  3e-20
pir||E82175 conserved hypothetical protein VC1631 [imported] - V...   100  3e-20
pir||C72561 hypothetical protein APE1773 - Aeropyrum pernix (str...    99  7e-20
pir||H81402 probable integral membrane protein Cj0560 [imported]...    99  1e-19
dbj|BAB07764.1| (AP001520) unknown conserved protein in others [...    99  1e-19
gb|AAG19201.1| (AE005016) DNA damage-inducible protein; Dip2 [Ha...    98  3e-19
pir||F69906 conserved hypothetical protein yojI - Bacillus subti...    96  1e-18
dbj|BAA31456.1| (AB010463) NorM [Vibrio parahaemolyticus]              93  6e-18
pir||T36597 hypothetical protein SCH24.32c - Streptomyces coelic...    91  2e-17
gb|AAF21214.1|AC013483_38 (AC013483) putative integral membrane ...    91  3e-17
pir||C81156 conserved hypothetical protein NMB0812 [imported] - ...    91  3e-17
pir||D81950 probable transmembrane efflux protein NMA1022 [impor...    90  6e-17
dbj|BAB04579.1| (AP001510) unknown conserved protein [Bacillus h...    89  1e-16
pir||B83476 probable transporter PA1361 [imported] - Pseudomonas...    87  3e-16
pir||H82186 probable multidrug resistance protein NorM VC1540 [i...    86  9e-16
sp|P37340|YDHE_ECOLI HYPOTHETICAL 49.4 KDA PROTEIN IN RIBC-PYKF ...    79  9e-14
pir||H75559 conserved hypothetical protein - Deinococcus radiodu...    79  9e-14
pir||F70172 conserved hypothetical integral membrane protein BB0...    77  4e-13
pir||A64924 probable membrane protein ydhE precursor - Escherich...    77  5e-13
gb|AAD30646.1|AC006085_19 (AC006085) Hypothetical protein [Arabi...    77  5e-13
gi|8922709 hypothetical protein FLJ10847 [Homo sapiens] >gi|7023...    76  1e-12
pir||E82527 multidrug efflux protein XF2686 [imported] - Xylella...    75  2e-12
pir||T50435 conserved hypothetical protein SPCC4B3.13 [imported]...    73  7e-12
pir||G70693 probable dinF protein - Mycobacterium tuberculosis (...    73  9e-12
pir||A82984 hypothetical protein PA5294 [imported] - Pseudomonas...    71  4e-11
gb|AAC67367.1| (AC005499) hypothetical protein [Arabidopsis thal...    70  5e-11
gb|AAG27731.1|AF312031_1 (AF312031) multi-drug efflux transporte...    69  8e-11
dbj|BAA97535.1| (AB028606) emb|CAA66809.1~gene_id:F16F17.3~stron...    69  8e-11
dbj|BAB10095.1| (AB023028) gb|AAF34304.1~gene_id:K20J1.11~strong...    69  8e-11

>pir||B75053 dinf related PAB1439 - Pyrococcus abyssi (strain Orsay)
           >gi|5458832|emb|CAB50319.1| (AJ248287) dinF related
           [Pyrococcus abyssi]
           Length = 468
           
 Score =  913 bits (2334), Expect = 0.0
 Identities = 468/468 (100%), Positives = 468/468 (100%)

Query: 1   MSMEKVKAMRREILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGV 60
           MSMEKVKAMRREILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGV
Sbjct: 1   MSMEKVKAMRREILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGV 60

Query: 61  AWPIIGTLMALGMGFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILI 120
           AWPIIGTLMALGMGFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILI
Sbjct: 61  AWPIIGTLMALGMGFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILI 120

Query: 121 LPLALDFMNVTPSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVF 180
           LPLALDFMNVTPSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVF
Sbjct: 121 LPLALDFMNVTPSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVF 180

Query: 181 LNIILDPIFIFIFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFY 240
           LNIILDPIFIFIFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFY
Sbjct: 181 LNIILDPIFIFIFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFY 240

Query: 241 SKIVRVGLPSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAM 300
           SKIVRVGLPSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAM
Sbjct: 241 SKIVRVGLPSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAM 300

Query: 301 GTMVAQNVGAEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESK 360
           GTMVAQNVGAEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESK
Sbjct: 301 GTMVAQNVGAEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESK 360

Query: 361 IVLEYFLISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITF 420
           IVLEYFLISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITF
Sbjct: 361 IVLEYFLISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITF 420

Query: 421 LGIRIPMAELFNFTSRGVFFGMGLSNFLAAIIGLAWFLKGSWMRRIID 468
           LGIRIPMAELFNFTSRGVFFGMGLSNFLAAIIGLAWFLKGSWMRRIID
Sbjct: 421 LGIRIPMAELFNFTSRGVFFGMGLSNFLAAIIGLAWFLKGSWMRRIID 468


>pir||C71172 hypothetical protein PH0575 - Pyrococcus horikoshii
           >gi|3256981|dbj|BAA29664.1| (AP000002) 472aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 472
           
 Score =  790 bits (2018), Expect = 0.0
 Identities = 392/468 (83%), Positives = 431/468 (91%), Gaps = 9/468 (1%)

Query: 1   MSMEKVKAMRREILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGV 60
           MS+EK K MR+EILEGPIE TL KLAWPI++NNLIQVLYNITDTFWLGKLGR ALSAPGV
Sbjct: 14  MSIEKAKMMRKEILEGPIEGTLFKLAWPIIINNLIQVLYNITDTFWLGKLGRAALSAPGV 73

Query: 61  AWPIIGTLMALGMGFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILI 120
           +WPIIGTLMALG+GFTMAGFSIVGQYIGAG+F+KANRSAGALFSL++FFST SA++SILI
Sbjct: 74  SWPIIGTLMALGIGFTMAGFSIVGQYIGAGNFEKANRSAGALFSLIIFFSTASAILSILI 133

Query: 121 LPLALDFMNVTPSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVF 180
           LP AL FM+VT SIRPYAY+Y+++IFAGVP+SFLFM FN LMRA GDT+TPVKIS +TVF
Sbjct: 134 LPYALSFMHVTSSIRPYAYKYSLIIFAGVPMSFLFMTFNVLMRAIGDTRTPVKISLITVF 193

Query: 181 LNIILDPIFIFIFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFY 240
           LNIILDPIFIFI  LGV GAALATVLSN+VGT+IGV+IL SG+AGLKI+ E+LKPDWKFY
Sbjct: 194 LNIILDPIFIFILNLGVEGAALATVLSNSVGTVIGVRILTSGRAGLKISRENLKPDWKFY 253

Query: 241 SKIVRVGLPSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAM 300
           SKIVR+GLPSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAM
Sbjct: 254 SKIVRIGLPSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAM 313

Query: 301 GTMVAQNVGAEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESK 360
            TMVAQN+GAE YERAKVIAERTMV+NF IAG AVL+IG+FRVPIFKVFL+DP VIAESK
Sbjct: 314 STMVAQNIGAENYERAKVIAERTMVINFLIAGIAVLIIGIFRVPIFKVFLNDPMVIAESK 373

Query: 361 IVLEYFLISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITF 420
           IVLEYFLISVPFFNGIFVVVTG FSS+GHTVKSM+MSMLRLWGFRIPLSY FGY+P    
Sbjct: 374 IVLEYFLISVPFFNGIFVVVTGAFSSSGHTVKSMIMSMLRLWGFRIPLSYVFGYVPT--- 430

Query: 421 LGIRIPMAELFNFTSRGVFFGMGLSNFLAAIIGLAWFLKGSWMRRIID 468
                  A+LF FTSRGVFFGMGLSNFLAAI+GLAWFLKGSWMR+II+
Sbjct: 431 ------FAKLFGFTSRGVFFGMGLSNFLAAIVGLAWFLKGSWMRKIIE 472


>pir||C75053 DNA damage-inducible protein. PAB1438 - Pyrococcus abyssi  (strain
           Orsay) >gi|5458833|emb|CAB50320.1| (AJ248287) DNA
           DAMAGE-INDUCIBLE PROTEIN. [Pyrococcus abyssi]
           Length = 449
           
 Score =  526 bits (1341), Expect = e-148
 Identities = 258/466 (55%), Positives = 339/466 (72%), Gaps = 17/466 (3%)

Query: 3   MEKVKAMRREILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAW 62
           M  ++  R EIL G IEKTLL+LA+P+++NNL+QV+YN+TDTFWL KLGR  LSAPG  W
Sbjct: 1   MANIERTREEILSGSIEKTLLRLAYPLIINNLVQVMYNLTDTFWLAKLGRSELSAPGTVW 60

Query: 63  PIIGTLMALGMGFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILP 122
           P++  +M+LG GF +AGF++V QYIGAG++KKA+R AG+L+SL+L  S L A I I+I P
Sbjct: 61  PLLWFMMSLGSGFVVAGFAMVSQYIGAGEYKKASRVAGSLYSLLLMLSLLLAGIGIVISP 120

Query: 123 LALDFMNVTPSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLN 182
            AL F+ VTP + PYA +Y I IFAGVPV+     FN ++RA GDTKTPVK++ LT+ LN
Sbjct: 121 FALRFIKVTPDVYPYALKYMIAIFAGVPVALTLHTFNFVLRAAGDTKTPVKVNILTIILN 180

Query: 183 IILDPIFIFIFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSK 242
           IILDP+FIFI  +GVLGAA+AT++S  +G+IIG  +L +GK G+KI+ +DL+PD   Y K
Sbjct: 181 IILDPVFIFILDMGVLGAAIATIISEGIGSIIGGYLLFTGKVGIKISRDDLRPDVNLYIK 240

Query: 243 IVRVGLPSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGT 302
             ++GLP+SIG S NSFGFV+L RII  +G V +A Y IT RL NF+ + + GIS AMGT
Sbjct: 241 TFKIGLPASIGDSTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGT 300

Query: 303 MVAQNVGAEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIV 362
           MV QN+GAE Y+RA+ +A + M  NF I  F  L+   FR  IF+ F++DP +I ES+ V
Sbjct: 301 MVGQNIGAENYKRAREVAIKAMATNFLILVFGTLLFMAFREEIFRFFINDPGIIKESEKV 360

Query: 363 LEYFLISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLG 422
           ++YF  S PFF GIF  VT VF+SAGHT K++++ ++RLWG RIPLSY  G     T LG
Sbjct: 361 VKYFAASFPFF-GIFSAVTNVFASAGHTKKNLILGIIRLWGLRIPLSYYLG-----TTLG 414

Query: 423 IRIPMAELFNFTSRGVFFGMGLSNFLAAIIGLAWFLKGSWMRRIID 468
                       S GV+ GMGLSN ++A+IG AWFLKGSWMRRI++
Sbjct: 415 -----------DSAGVWIGMGLSNVISALIGFAWFLKGSWMRRIVE 449


>pir||E71172 probable damage-inducible protein - Pyrococcus horikoshii
           >gi|3256983|dbj|BAA29666.1| (AP000002) 449aa long
           hypothetical damage-inducible protein [Pyrococcus
           horikoshii]
           Length = 449
           
 Score =  517 bits (1317), Expect = e-145
 Identities = 248/466 (53%), Positives = 338/466 (72%), Gaps = 17/466 (3%)

Query: 3   MEKVKAMRREILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAW 62
           M  ++  R EIL G IEKTL++LA+P+++NNL+QV+YN+TDTFWL KLGR  LSAPG  W
Sbjct: 1   MANIEKAREEILSGSIEKTLIRLAYPLIINNLVQVMYNLTDTFWLAKLGRAELSAPGTVW 60

Query: 63  PIIGTLMALGMGFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILP 122
           P++  ++++G GF +AGF++V QY+GAG++KKA++ AG+L+SL+L  ST+ A + ILI P
Sbjct: 61  PLLWFMISIGSGFAVAGFAMVSQYVGAGEYKKASKVAGSLYSLLLALSTIIAFLGILISP 120

Query: 123 LALDFMNVTPSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLN 182
           LAL F+ VTP + PYA +Y  ++F G+P++     FN ++RA GDTKTPVK++ LT+ LN
Sbjct: 121 LALKFIKVTPDVYPYALKYMKIVFGGIPIALTLYAFNFILRAVGDTKTPVKVNILTILLN 180

Query: 183 IILDPIFIFIFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSK 242
           IILDP+FIF    GVLGAALATV+S   G++IG  +L +G+  +K++LEDL PD K Y K
Sbjct: 181 IILDPVFIFGLNYGVLGAALATVISEGTGSVIGGYLLFTGRVSIKLSLEDLSPDIKLYIK 240

Query: 243 IVRVGLPSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGT 302
             ++GLP+SI +S NSFGFV+L RII  +G V +A Y IT RL NF+ + + GIS AMGT
Sbjct: 241 TFKIGLPASISESTNSFGFVLLNRIIYTYGTVAFATYTITNRLTNFMFAFADGISQAMGT 300

Query: 303 MVAQNVGAEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIV 362
           MV QNVGAEKYERAK IA + M+ NF I  F  ++  +FR  IF+ F++DP ++ ES+ V
Sbjct: 301 MVGQNVGAEKYERAKEIAIKAMLTNFLILIFGTMLFIIFREEIFRFFINDPGILKESEKV 360

Query: 363 LEYFLISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLG 422
           ++YF  S PFF GIF  VT VF+SAGHT K++ + ++RLWG RIPLSY         +LG
Sbjct: 361 VKYFAASFPFF-GIFSAVTNVFASAGHTKKNLTLGLIRLWGLRIPLSY---------YLG 410

Query: 423 IRIPMAELFNFTSRGVFFGMGLSNFLAAIIGLAWFLKGSWMRRIID 468
             +         S GV+ GMGLSN +AA++G  WFLKGSWMRRI++
Sbjct: 411 KTLK-------DSAGVWIGMGLSNVIAALVGFLWFLKGSWMRRIVE 449


>gb|AAG19206.1| (AE005017) Vng0727c [Halobacterium sp. NRC-1]
           Length = 494
           
 Score =  238 bits (601), Expect = 1e-61
 Identities = 156/471 (33%), Positives = 238/471 (50%), Gaps = 38/471 (8%)

Query: 12  EILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMAL 71
           ++  G I K L  LA PIV+ NL Q  YN+ DTFWLG+   +AL+A   A+P++  L++L
Sbjct: 18  DLTSGRIGKPLFFLAMPIVITNLFQTAYNLADTFWLGQYNTDALAAISFAFPMVFLLISL 77

Query: 72  GMGFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVT 131
           GMG ++AG  +V QY GAG  ++A  +A    +  +  S L   I    +   L  +  +
Sbjct: 78  GMGISVAGSVLVAQYTGAGKDEQAEYAASQTVTFSVLASLLLGGIGYFFVEDFLSVVGAS 137

Query: 132 PSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF 191
            ++   A  Y  V+  G+   F F VF ALMR  GDT TP+ +   +V LNI+LDP  IF
Sbjct: 138 DAVLRPATSYMQVVALGLAAMFGFAVFIALMRGYGDTITPMLVMFGSVVLNIVLDPFLIF 197

Query: 192 IF---------------KLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPD 236
            +               +LG+ GAA+ATV S A+   +G+ I+  G  G++I   D+ PD
Sbjct: 198 GWTVVENAPLVGTVSFPRLGIQGAAIATVFSRALAFAVGLAIMFRGTRGVEINAADMLPD 257

Query: 237 WKFYSKIVRVGLPSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGI 296
             +  ++VR+GLP+SI  +  +    +L  I+  F D   AAY I TR+ + +   +  I
Sbjct: 258 LSYLRRLVRIGLPASIEGTGRALSMNLLLFIVATFPDHIVAAYGIGTRVFSVVFLPAIAI 317

Query: 297 SMAMGTMVAQNVGAEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFL-----D 351
           +  + TM  QNVGA K +RA   A     + F +     L++  +  PI  VF+     +
Sbjct: 318 ARGVETMTGQNVGAGKPDRAARAARLAATMLFGVLSVLGLIVYWYPEPIVSVFVGAGQEN 377

Query: 352 DPEVIAESKIVLEYFLISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYA 411
             +VI      L Y  ++  F  GI    TG F  AG T+ +  +S++ L   R PL++A
Sbjct: 378 SAQVIEAGSQFLRYVALTFGFI-GIARAYTGSFRGAGKTMVAAAISVITLGVIRFPLAWA 436

Query: 412 FGYIPAITFLGIRIPMAELFNFTSRGVFFGMGLSNFLAAIIGLAWFLKGSW 462
                 I  LG            S G++    +SN + AII  AW+ +G+W
Sbjct: 437 -----TIGSLG------------SAGIWLSFAVSNVIGAIIAYAWYRRGTW 470


>pir||E72471 probable DNA-damage-inducible protein APE2414 - Aeropyrum pernix
           (strain K1) >gi|5106118|dbj|BAA81429.1| (AP000064) 480aa
           long hypothetical DNA-damage-inducible protein
           [Aeropyrum pernix]
           Length = 480
           
 Score =  227 bits (572), Expect = 3e-58
 Identities = 145/471 (30%), Positives = 222/471 (46%), Gaps = 22/471 (4%)

Query: 1   MSMEKVKAMRREILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGV 60
           +  E +   R  + +GPI K +L LA PIV   L+       D  +LG++  E L+AP  
Sbjct: 6   LDREALDRKRTWVTQGPIVKVILALATPIVAARLLAATQESVDAIFLGRVSTEDLAAPAA 65

Query: 61  AWPIIGTLMALGMGFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILI 120
           A P++     LG+G      ++V Q IGA D+  A R A  L    L     SAL  IL 
Sbjct: 66  ASPLLWLFAGLGIGINTTLSALVSQAIGARDYASAQRYASKLLGATLMLGAASALAIILT 125

Query: 121 LPLALDFMNVTPSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVF 180
                            A  Y +V   G+P       FNA+M A+GDT+TP K+SAL+  
Sbjct: 126 AETVFILQGFQGRSLEVALAYTLVEAVGMPFMLALFYFNAVMAASGDTRTPFKVSALSSI 185

Query: 181 LNIILDPIFIF----IFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPD 236
           LN+ILDPI IF    +  LG +GAA+ATVL+ A    I   +L+ G  G ++  +   PD
Sbjct: 186 LNVILDPILIFGLILLPPLGAVGAAVATVLARAAAVSIAFYLLLRGAPGFRV--KPSMPD 243

Query: 237 WKFYSKIVRVGLPSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGI 296
            +    I+R+G P S+ +   S GF+V+  I+   G    AAY ++  +++ + S + G 
Sbjct: 244 RQLIGHILRIGGPVSLQRLVVSMGFLVMMGIVARLGAPVVAAYNVSLVIIHIVQSATFGF 303

Query: 297 SMAMGTMVAQNVGAEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVI 356
           ++A  T+V QN+GA    RA   A   + + F +     + I   R  +  +F    EV 
Sbjct: 304 NIATATVVGQNLGASNISRAVRAAYTGVALVFGLLSIGAVAIVGGRSMLVSLFTSIEEVQ 363

Query: 357 AESKIVLEYFLISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIP 416
             ++ ++    + +PF  G F    GV   +G T     + + RLW  RIP +Y   YI 
Sbjct: 364 FYAERMISIVALGMPFL-GAFFTAMGVARGSGRTAFISALGIARLWLLRIPAAYTLVYI- 421

Query: 417 AITFLGIRIPMAELFNFTSRGVFFGMGLSNFLAAIIGLAWFLKGSWMRRII 467
                         ++    GV+  M LSN +A  + +AW    +W + I+
Sbjct: 422 --------------YSLGDMGVWLAMTLSNIIAGTLAIAWVAGRTWAKPIV 458


>pir||H70158 conserved hypothetical integral membrane protein BB0473 - Lyme
           disease spirochete >gi|2688416|gb|AAC66867.1| (AE001152)
           conserved hypothetical integral membrane protein
           [Borrelia burgdorferi]
           Length = 454
           
 Score =  214 bits (539), Expect = 2e-54
 Identities = 137/469 (29%), Positives = 234/469 (49%), Gaps = 22/469 (4%)

Query: 1   MSMEKVKAMRREILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGV 60
           MS +K K  R  IL G + K L  +++PIV+ N+IQ  Y++TD F++GKLG   LSA  +
Sbjct: 1   MSTDKSKT-RELILNGNLYKVLFLISFPIVITNIIQAFYDLTDMFYVGKLGAMPLSALSL 59

Query: 61  AWPIIGTLMALGMGFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILI 120
           A P+   ++A+ MG      S++ + IG G+F + +R AG L  L    S    + +   
Sbjct: 60  AGPVNFFIIAIAMGMATGSISLMSKCIGEGNFSRFSRYAGQLIVLNFVLSLFVTICAFFF 119

Query: 121 LPLALDFMNVTPSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVF 180
           +   LD + V   ++  +  Y  V    +P+ FL +    ++ A G+T   + I      
Sbjct: 120 IDHLLDLLGVKGELKELSRVYFYVTIFAIPIMFLSISITYILNAQGETILSMTIVLFANI 179

Query: 181 LNIILDPIFIFIFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFY 240
           +N ILDPI IF F +G+ GAA AT+ S  +  +  + +      GLKI L+DL  D +  
Sbjct: 180 VNFILDPILIFSFNMGITGAAWATLFSKLLTVVFYLFLTYRLNYGLKIHLKDLVIDIRSI 239

Query: 241 SKIVRVGLPSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAM 300
            +IV +GLPS+ GQ   S  F +   I++       AAY +T  +++F+   + GI   +
Sbjct: 240 KEIVNLGLPSTFGQIMVSLSFFIFNYIVIEISPKFLAAYGLTNTIISFLFLPAMGIGTGI 299

Query: 301 GTMVAQNVGAEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESK 360
            ++V QN+GA+K  R + + ++   ++ AI      ++   +  I ++F +D EV+  + 
Sbjct: 300 ISIVGQNLGAKKVNRVEEVLKKGFFISLAILLIINSIVIFNKQFILRLFTNDLEVLNYAN 359

Query: 361 IVLEYFLISV--PFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAI 418
               Y L++    F  G+  V  G    +G T  +M++  +RLW  R+P+ + F Y    
Sbjct: 360 ---NYLLLTTIGTFGYGLQQVFFGGLIGSGRTKIAMIVIFIRLWLIRLPVVFIFQY---- 412

Query: 419 TFLGIRIPMAELFNFTSRGVFFGMGLSNFLAAIIGLAWFLKGSWMRRII 467
                       F      + +   +SN+LA II +A+     W++ I+
Sbjct: 413 ------------FGIMENSLGYAFIISNYLAIIILIAFTCTRYWVKPIL 449


>dbj|BAB04605.1| (AP001510) unknown conserved protein [Bacillus halodurans]
           Length = 454
           
 Score =  192 bits (483), Expect = 7e-48
 Identities = 120/454 (26%), Positives = 222/454 (48%), Gaps = 21/454 (4%)

Query: 12  EILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKL-GREALSAPGVAWPIIGTLMA 70
           +  EG I K ++  +WPI ++NL+Q  Y ITD+ W+G L G  AL A  ++  ++  +++
Sbjct: 7   DFTEGSITKKMVVFSWPIFLSNLLQTSYQITDSLWVGNLLGASALGALSISATVVFMVLS 66

Query: 71  LGMGFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNV 130
             +G   A  +++ Q  GA D      S  A   ++   + L  LI        L  +  
Sbjct: 67  FIIGLNGATLTVLSQRQGAKDEAGLKASLNAFVFVLGLLAILLGLIGYFSASSILQLLGT 126

Query: 131 TPSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFI 190
              I P A  Y  + F G+   F +     ++RA GD+++PV+   + V LNIILDP+ I
Sbjct: 127 PEEILPLAESYLKINFIGILFLFGYNFIGTVLRAMGDSRSPVRFIFIAVILNIILDPLMI 186

Query: 191 FIFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPS 250
             F LG+ GAA AT++S     I G+ I    KAG+   +  + P+ +++  + ++GLP+
Sbjct: 187 AGFNLGIDGAAYATIVSQGTAFIYGL-IYSVRKAGVPFQIPYV-PEKRYFFVLFKLGLPA 244

Query: 251 SIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGA 310
            +     S G   +  ++  FG+   A +    RL + I   +  +  A+ T+  QN+GA
Sbjct: 245 GLSMITISAGVTAILSVVTSFGEEAVAGFGAAQRLDSLIMLPALTLGSAVNTIAGQNIGA 304

Query: 311 EKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISV 370
            K+ER +  A++ +++  A+     L+  +      ++F+ D   +A   + ++      
Sbjct: 305 NKWERVRATAKQGVMLIIAVTLIIGLITFIGAQFFIRLFVRDEATVAFGAMYIQTIAFFY 364

Query: 371 PFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLGIRIPMAEL 430
           PF  GI  V+ G+  ++G     ++++++  W  R PL+Y                M++L
Sbjct: 365 PFL-GINFVLNGIVRASGAMFPVLLLNIISFWILRYPLTYW---------------MSDL 408

Query: 431 FNFTSRGVFFGMGLSNFLAAIIGLAWFLKGSWMR 464
           F    RG+  GMG +  ++++I   ++  G+W +
Sbjct: 409 FG--ERGIALGMGFAFVVSSLIATGYYFLGNWRK 440


>sp|P54181|YPNP_BACSU HYPOTHETICAL 48.5 KD PROTEIN IN ILVA 3'REGION
           >gi|7474682|pir||D69939 conserved hypothetical protein
           ypnP - Bacillus subtilis >gi|1256651|gb|AAA96645.1|
           (L77246) 21% identity with the NADH-dehydrogenase
           (ubiquinone) of Caenorhabditis elegans; putative
           [Bacillus subtilis] >gi|2634591|emb|CAB14089.1| (Z99115)
           similar to hypothetical proteins [Bacillus subtilis]
           Length = 445
           
 Score =  178 bits (447), Expect = 1e-43
 Identities = 108/433 (24%), Positives = 215/433 (48%), Gaps = 4/433 (0%)

Query: 12  EILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKL-GREALSAPGVAWPIIGTLMA 70
           +  +G + K L+  + PI++ N +QV +   D+ W+G L G +AL A  V+  I+ T+++
Sbjct: 5   DFTQGNVLKQLVLFSMPIMLGNALQVSFQFIDSLWIGNLLGAKALGAAAVSSTIVLTVLS 64

Query: 71  LGMGFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNV 130
             +G   A  +I+ Q  G  D K       A   L+   S         +  L L  +  
Sbjct: 65  FILGLNNATLTILSQQKGKDDIKGMASYINAFVVLLTGLSIGFGAAGFFLSELLLRLLKT 124

Query: 131 TPSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFI 190
             S+ P A  Y  + F G+   F +   + ++RA GD+KTP++  A  V LN +L P+FI
Sbjct: 125 PESMIPLAETYLQIQFIGILFLFGYNFISTVLRALGDSKTPLRFIAFAVVLNTVLAPLFI 184

Query: 191 FIFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPS 250
            +F++G+ GAA +T+LS  +  + G+  ++  K  +  ++  + P W+  + I+++G+P+
Sbjct: 185 SVFRMGIAGAAYSTILSQGIAFLYGLFYVIKHKL-VPFSIPRM-PKWEESALILKLGIPA 242

Query: 251 SIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGA 310
            +     + G + +  ++  +GD   + +    RL + IT  +     A+ +M  QN+G 
Sbjct: 243 GLQMMVITGGMMAIMSVVNSYGDHVVSGFGAVQRLDSIITLPAMAAGTAVNSMAGQNIGI 302

Query: 311 EKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISV 370
              +R   IA   ++   +      ++I VF   + ++F+ +P+ +A  +  L++     
Sbjct: 303 GNEKRVGTIARLGVIAVISCMLVIAVMIWVFGKYLIRLFISEPDAVAFGEQYLKWIAFFY 362

Query: 371 PFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLGIRIPMAEL 430
           PF  G+  V+ G+  +AG  ++ +V++++  W  R P +  F        +G+ I M+ L
Sbjct: 363 PFI-GVNFVLNGIVRAAGAMLQVLVLNLISFWVLRYPFTALFSAWLGQKGIGLGIGMSFL 421

Query: 431 FNFTSRGVFFGMG 443
           F+  +  +++  G
Sbjct: 422 FSSCAAFLYYRYG 434


>pir||H72331 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
           >gi|4981345|gb|AAD35897.1|AE001748_13 (AE001748)
           conserved hypothetical protein [Thermotoga maritima]
           Length = 464
           
 Score =  175 bits (439), Expect = 1e-42
 Identities = 125/458 (27%), Positives = 218/458 (47%), Gaps = 29/458 (6%)

Query: 18  IEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVA----WPIIGTLMALGM 73
           I K L+KLA P +  N++Q+L+ + DT +LG    +A+S  G++    W +   L+A  M
Sbjct: 18  IRKELIKLALPAMGENVLQMLFGMADTAFLGHYSWKAMSGVGLSNQVFWVVQVVLIAASM 77

Query: 74  GFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPS 133
           G T+     +   IGAG+ K     A     L +F   +   ++ L   L   F N+   
Sbjct: 78  GATVT----IANAIGAGNRKAVRSLAWNSVFLAIFTGVILTALTPLSDVLINIFPNLEGE 133

Query: 134 IRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF-- 191
           I   A  Y  VI +G     +  VF+A++R  GDT+TP+ ++ LT FLNI LD   IF  
Sbjct: 134 IESSAKEYLKVILSGSMGFSIMAVFSAMLRGAGDTRTPMIVTGLTNFLNIFLDYAMIFGK 193

Query: 192 --IFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLP 249
               ++GV GAA+AT+LS  VG  I   ++   +   ++    + P W    +I+RVG P
Sbjct: 194 FGFPEMGVRGAAVATILSRFVGAGILTYVIFK-REEFQLRKGLVPPKWSSQKEILRVGFP 252

Query: 250 SSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVG 309
           ++I     S G ++   I++  G   YA + I   + +     + GIS+A+ T+V +  G
Sbjct: 253 TAIENFVFSTGVLMFANILLIAGAEAYAGHRIGINVESLSFMPAFGISVAITTLVGRYNG 312

Query: 310 AEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLIS 369
               E    +  +  +++        ++I +F  P+ ++F  DP++I  SK+ ++   + 
Sbjct: 313 MGNKEHVLGVIRQGWILSLLFQVTVGIIIFLFPEPLIRIFTSDPQIIEISKLPVKIIGL- 371

Query: 370 VPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLGIRIPMAE 429
             FF  I   + G     G+T+  M+++ + +W  R+P+++                M +
Sbjct: 372 FQFFLAIDSTMNGALRGTGNTLPPMIITFISIWTARLPVAFV---------------MVK 416

Query: 430 LFNFTSRGVFFGMGLSNFLAAIIGLAWFLKGSWMRRII 467
            F     G + GM       + + L +FL G W +R +
Sbjct: 417 YFQLGLLGAWIGMIADIIFRSTLKLLFFLSGKWEKRAV 454


>dbj|BAB05882.1| (AP001514) unknown conserved protein in others [Bacillus
           halodurans]
           Length = 464
           
 Score =  173 bits (433), Expect = 5e-42
 Identities = 117/435 (26%), Positives = 219/435 (49%), Gaps = 15/435 (3%)

Query: 18  IEKTLLKLAWPIVVNNLIQVLYNITDTFWLG-KLGREALSAPGVAWPIIGTLMALGMGFT 76
           I K L  L+ P ++   +  LYN+ DT ++   +G E ++   +A+PI+  +M++     
Sbjct: 15  IPKLLRSLSIPAMIGMFVMALYNVVDTIFISYAVGIEGVAGVTIAFPIMMIMMSMAGALG 74

Query: 77  MAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRP 136
           + G S++ + +G    ++AN+  G + +++L  S +  + +  +L  AL     T   + 
Sbjct: 75  IGGASVISRRLGERRGEEANQVFGNILTVILVLSVIGFISAFTLLGPALQLFGATSVTQG 134

Query: 137 YAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIFIFKLG 196
           YA  Y   I  G    F     N ++R+ G+    +    +   LNI+LD +FIF   +G
Sbjct: 135 YATDYLFPILLGSIFFFFAFAANNIIRSEGNATFAMVTMIVPAVLNILLDVLFIFGLNMG 194

Query: 197 VLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPSSIGQSA 256
           VLGA++ATV++ A  T + ++  ++GK+ L +   DL+       ++  VGLP+ + QS+
Sbjct: 195 VLGASIATVIAQASVTGLVLRYFLTGKSTLSLHWSDLRMKGSVIKEVCLVGLPAFVQQSS 254

Query: 257 NSFGFVVLTRIIMGFG-DVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEKYER 315
            S   + +  +++ FG D     + +  R++ F+     GI  AM  +V  N GA++Y R
Sbjct: 255 ASLMMIAINSMLLRFGSDFYVGVFGLVQRIMMFVMMPMMGIMQAMQPIVGYNYGAKQYSR 314

Query: 316 AK--VIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISVPFF 373
            +  V+    +   F+I  FA+L++  F   + +VF  D EVI ++ +   + L  V F 
Sbjct: 315 LRETVMLGFKVATIFSIGIFALLML--FPEALLRVFTADREVI-QAGVSAMHILFCVTFL 371

Query: 374 NGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLGIRIPMAELFNF 433
            G  +V  G++ S G   +++++S+ R   F IPL     +I  ++ +    P+A++ +F
Sbjct: 372 IGAQIVAGGLYQSLGKPKQALILSLSRQIIFLIPLVLILPHIFGLSGVWWAFPIADVLSF 431

Query: 434 --------TSRGVFF 440
                     R VFF
Sbjct: 432 ILTVVLLYRDRNVFF 446


>pir||A75151 damage-inducible protein PAB0243 - Pyrococcus abyssi (strain Orsay)
           >gi|5457798|emb|CAB49288.1| (AJ248284) DAMAGE-INDUCIBLE
           PROTEIN [Pyrococcus abyssi]
           Length = 463
           
 Score =  170 bits (427), Expect = 3e-41
 Identities = 126/462 (27%), Positives = 215/462 (46%), Gaps = 20/462 (4%)

Query: 18  IEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTM 77
           I K L  LAWP ++ N+ Q L N+ DT  +G +   AL A G+   +   +  + M  + 
Sbjct: 4   IRKKLWTLAWPAIMGNISQTLLNLVDTMIVGHVSSVALGAVGLGGQVSWFMFPIMMAIST 63

Query: 78  AGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRPY 137
              ++V + +G  +F++A+R A     +         L  + +    L  M     +   
Sbjct: 64  GTLALVARRVGEKNFEEASRIAEQSMYIAFIIGIPVMLFGLFLGDEVLKIMGAKGEVLEI 123

Query: 138 AYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF----IF 193
           AY Y  V+F   P+ F+   F + +R  GDTKTP+K++ L   +N +LD + +F      
Sbjct: 124 AYAYLRVLFLFYPIRFMGFAFFSALRGAGDTKTPMKLNILMNVINAVLDYLLVFGKFGFP 183

Query: 194 KLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPSSIG 253
           +LG +GAA A+ +   +  ++G+ + ++ K  LK  L DL   +    KI+R+G P+ + 
Sbjct: 184 RLGPVGAAWASGIGITIAFLVGMYLFITNKLILKPVL-DLSLRFDIIEKILRIGTPTMLE 242

Query: 254 QSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEKY 313
           +   SF   +   I+  FG +  +A+ I  R+ +     + G S+A   +V QN+GA+K 
Sbjct: 243 RGLFSFYNFLYVSIVARFGKIALSAHYIGLRIESIAYMPAFGFSIATSALVGQNLGAKKP 302

Query: 314 ERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFL--DDPEVIAESKIVLEYFLI--- 368
           E A+   +  + +          V+ VF   + + FL  +DP   A   + + Y +I   
Sbjct: 303 EEAERTVKEALKMTTMFMSAMAFVLMVFPGYLTEPFLSHNDPNYQAVKSLAVIYLIIVGI 362

Query: 369 -SVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLGIRIPM 427
             +P   G+  V++G    AG T   + ++ +    FRI  +Y  G+   I  L I    
Sbjct: 363 SEIPL--GMTFVLSGALRGAGDTKSPLYVTSVSKLLFRILPAYLLGFGFEIPELSIGPFT 420

Query: 428 AELFNFTSRGV---FFGMGLSNFLAAIIGLAW--FLKGSWMR 464
              F F   GV   + GM L  F+ A  GL W  F +G W +
Sbjct: 421 FPGFKFPGMGVIAAWIGMSLETFVTA--GLFWLVFKRGKWKK 460


>pir||G71191 probable DNA damage-inducible protein - Pyrococcus horikoshii
           >gi|3258243|dbj|BAA30926.1| (AP000007) 463aa long
           hypothetical DNA damage-inducible protein [Pyrococcus
           horikoshii]
           Length = 463
           
 Score =  170 bits (426), Expect = 3e-41
 Identities = 122/463 (26%), Positives = 218/463 (46%), Gaps = 26/463 (5%)

Query: 18  IEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTM 77
           + + L +LAWP ++ N+ Q L N+ DT  +G +   AL A G+   +   +  + M  + 
Sbjct: 4   LRRRLWELAWPAIMGNISQTLLNLVDTMIVGHVSAVALGAVGLGGQVSWFMFPIMMAIST 63

Query: 78  AGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRPY 137
              ++V + +G G++++A+R       +         L  I +    L  M     +   
Sbjct: 64  GTLALVARRVGEGNYREASRITEQSMYIAFLIGIPVMLFGIFLGDEVLRIMGAKGEVLDI 123

Query: 138 AYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF----IF 193
           AY Y  ++F   P+ F+   F + +R  GDTKTP+K++ L   +N ILD + +F      
Sbjct: 124 AYSYLKILFLFYPIRFMGFAFFSALRGAGDTKTPMKLNILMNVINGILDYLLVFGKLGFP 183

Query: 194 KLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPSSIG 253
           KLG +GAA A+ +  +   ++G+ + ++ K  LK  LE  K  +    KI+R+G P+ + 
Sbjct: 184 KLGPVGAAWASGIGISSSFLVGLYLFLAHKLILKPVLE-FKLRFNIIEKILRIGTPTMLE 242

Query: 254 QSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEKY 313
           +   SF   +   I+  FG++  +A+ I  R+ +     + G S+A   +V Q +GA K 
Sbjct: 243 RGLFSFYNFLYVSIVARFGEIALSAHYIGLRVESIAYMPAFGFSIATSALVGQKLGARKP 302

Query: 314 ERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFL--DDPEVIAESKIVLEYFLI--- 368
           + A++  +  + +  A       ++  F   + + FL  +DP   A   + + Y +I   
Sbjct: 303 DEAELTVKEALKMTTAFMSTMAFILVAFPGYLTEPFLSHNDPNYSAVKSLAVIYLIIVGI 362

Query: 369 -SVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGY---IPAITFLGIR 424
             +P   G+  V++G    AG T   + ++ +    FRI  +Y  G+   +P+ T   + 
Sbjct: 363 SEIPL--GMTFVLSGALRGAGDTKSPLYVTSVSKLLFRIIPAYLLGFGFTVPSFTIGSLT 420

Query: 425 IPMAELFNFTSRGV---FFGMGLSNFLAAIIGLAW--FLKGSW 462
            P    F F   GV   + GM L  F+ A  GL W  F +G W
Sbjct: 421 FPG---FKFEGLGVIAAWIGMSLETFITA--GLFWIVFRRGKW 458


>pir||G72220 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
           >gi|4982278|gb|AAD36768.1|AE001810_7 (AE001810)
           conserved hypothetical protein [Thermotoga maritima]
           Length = 458
           
 Score =  162 bits (406), Expect = 8e-39
 Identities = 121/453 (26%), Positives = 223/453 (48%), Gaps = 30/453 (6%)

Query: 12  EILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMAL 71
           ++L G   K ++KL+ P+++  L+Q +YN+ D  W+  LG  AL+A G+ +P+   +++L
Sbjct: 11  KLLRGDPRKAIVKLSIPMMLAMLVQTIYNLADGIWVAGLGPYALAAIGLFFPVFMVIISL 70

Query: 72  GMGFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVT 131
             G  +   S+V Q IG  D + A+ +A     L +    LS  + +  +   L F    
Sbjct: 71  AAGIGVGASSVVSQKIGERDKEGADTAASVSILLSIVIGFLSIAVILPFISDILIFAGAQ 130

Query: 132 PSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF 191
                 A  Y++++   +P+     V N + R  GD K  +    +   LNI LDP+FI+
Sbjct: 131 GETLRLALEYSVILVYFIPLIMFNNVANGVFRGEGDAKRAMVAITIGSLLNIGLDPVFIY 190

Query: 192 IFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPSS 251
           +F +G+ GAA ATV+S AV +++ +   M  K    ++   LK D +   +I+++G+P+S
Sbjct: 191 VFGMGIRGAAYATVVSIAVSSLL-IAYWMFFKKDTYVSFR-LKWDGEILKRILKIGIPAS 248

Query: 252 IGQSANSFGFVVLTRI-IMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVG- 309
           + Q + S    VL    +   GD   A +    R++NF T    G++MA+ ++     G 
Sbjct: 249 LAQISMSVAIYVLNVFAVRSGGDYGVAVFTSAWRVINFGTVPLIGMAMAVTSVTGAAFGE 308

Query: 310 --AEKYERAKVIAERT-MVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEV---IAESKIVL 363
              EK E A + A +    V  A+  F +L+   +   +F    +  ++   + ++  +L
Sbjct: 309 RNGEKLETAHLYAVKLGFFVGLAVM-FTILIFAPYIARLFTYSQEGEKLYSDLVKALRIL 367

Query: 364 EYFLISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLGI 423
             FL  VPF  G+F   + +F   G  +KS++++++R    ++  S+ F ++       +
Sbjct: 368 SLFLPGVPF--GMF--TSSMFQGVGQGLKSLIVTIMRTVIMQVVFSWLFVFV-------L 416

Query: 424 RIPMAELFNFTSRGVFFGMGLSNFLAAIIGLAW 456
           RI +         GV++G+ L N  +A I   W
Sbjct: 417 RIGLV--------GVWWGIVLGNTTSAFITFNW 441


>pir||A82049 conserved hypothetical protein VC2671 [imported] - Vibrio cholerae
           (group O1 strain N16961) >gi|9657264|gb|AAF95812.1|
           (AE004332) conserved hypothetical protein [Vibrio
           cholerae]
           Length = 460
           
 Score =  162 bits (405), Expect = 1e-38
 Identities = 120/459 (26%), Positives = 228/459 (49%), Gaps = 40/459 (8%)

Query: 13  ILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALG 72
           +L  PI   L ++  P++   +  +++N+ DTF++  LG +AL+A    +P+   +  + 
Sbjct: 19  LLSAPIPLVLRQMTVPMIFGLVAILMFNLVDTFFISLLGTQALAAISYTFPVTFAVNCIT 78

Query: 73  MGFTMAGFSIVGQYIGAGDFKKANR-SAGALFSLVLFFSTLSALISILILPLALDFMNVT 131
           MG  +   + +G+ +G GD ++A R S+  L   +L  +  S L  + I PL L  +  +
Sbjct: 79  MGIGVGLSTCIGRLLGQGDGRQAARVSSHGLLLALLLVAAASTLGLLTIEPLFL-LLGAS 137

Query: 132 PSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF 191
             + P    Y +V +  +P+  L M  N+ +RATGDTKTP KI  L   +N  LDP+ IF
Sbjct: 138 HELIPLIKEYMVVWYLTIPLLVLPMAGNSAIRATGDTKTPAKIMMLAGLINGALDPLLIF 197

Query: 192 IF----KLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKI--TLEDLKPDWKFYSKIVR 245
            +    +LG+ GAA+A+  S  +G +IG   L+  +  L    +L  L+ DW+   +I++
Sbjct: 198 GYGPFPELGIQGAAIASAFS-WLGALIGSLYLLIKREKLLAIPSLPHLRDDWQ---QILK 253

Query: 246 VGLPSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVA 305
           +G P+++  + N     +L  ++   G    AAY  T R+ + +  +   ++ A+   +A
Sbjct: 254 IGTPAALSTAMNPISGALLMIMLSSHGTAAVAAYGATQRIESILILVLMSLTSALTPFMA 313

Query: 306 QNVGAEKYER--AKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVL 363
           QN+GA+   R  A +       + F +  F ++V     +P+  +F  +  V    + +L
Sbjct: 314 QNLGAQNPARSFAGLFLSLRFSLLFQLMVFIMMV--PLSIPLAALFSQEQAV----RDLL 367

Query: 364 EYFLISVPF---FNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITF 420
            ++L+ VP    F G+ +++    ++    +K+   S +RL+ F +P ++  G       
Sbjct: 368 WHYLLVVPVSYGFQGVVMMLVSALNALHQPLKAFQWSFMRLFVFTLPAAWIGG------- 420

Query: 421 LGIRIPMAELFNFTSRGVFFGMGLSNFLAAIIGLAWFLK 459
                    L+N    G+F G+ + N L  ++G  + L+
Sbjct: 421 --------RLYNI--EGLFIGIAVGNILGGLLGYLYALR 449


>sp|Q58119|Y709_METJA HYPOTHETICAL PROTEIN MJ0709 >gi|2128027|pir||E64388 conserved
           hypothetical protein homolog MJ0709 - Methanococcus
           jannaschii >gi|1591425|gb|AAB98703.1| (U67517) conserved
           hypothetical protein [Methanococcus jannaschii]
           Length = 450
           
 Score =  150 bits (376), Expect = 2e-35
 Identities = 103/421 (24%), Positives = 200/421 (47%), Gaps = 14/421 (3%)

Query: 12  EILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMAL 71
           EIL    +K +++++ PI+V   I+ +Y++ D+ W+  LG +AL+A G ++PI+ ++ A+
Sbjct: 5   EILLDDPKKAVIEVSKPIIVATFIESIYSLVDSIWVSGLGADALAAVGASFPILISIYAV 64

Query: 72  GMGFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVT 131
             G ++   S + + +GA + ++A++ A     L L    L  +     L      M   
Sbjct: 65  SWGLSIGISSGIARRVGAKNKEEADKVANHAIILALIAGILYIIAVYPNLDTLFSLMGTY 124

Query: 132 PSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF 191
              +  A +Y+ ++  G  +  +      + R  G+TK  +  S +    NIILDPIFI+
Sbjct: 125 GDCKSLAIKYSSILVLGTVIFTICDALYGIFRGEGNTKIVMIASVIGTLTNIILDPIFIY 184

Query: 192 IFKLGVLGAALATVLSNAVG-TIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPS 250
           +  LG+ GA+ AT+++  +   I+  ++ +     + + L   KPD K  + ++RVG+PS
Sbjct: 185 MLNLGISGASYATLIAIIISLLILAYELFIKKSCYVTVKLSKFKPDLKIIADLIRVGIPS 244

Query: 251 SIGQSANSFGFVVLTRIIMGFGDVT-YAAYVITTRLVNFITSISRGISMAMGTMVAQNVG 309
           ++ +   +  F ++T IIM  GD    A Y    R+  F      G++    +++    G
Sbjct: 245 ALIEITVAVSFFIMTSIIMMVGDSRGLAVYTGALRITEFGFIPMLGLASGATSVIGATYG 304

Query: 310 AEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIF-------KVFLDDPEVIAESKIV 362
           A  +E+ K     T+ +   +    V +I +   PI        K  +   E + ++  +
Sbjct: 305 ARSFEKLKTAYFYTIKIGVLMEIIIVALI-MLLSPILAYLFTYTKTSMGIHEELVKALRI 363

Query: 363 LEYFLISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLG 422
           +  +L+  PF     +  + +F   G   KS+++S+ R     I  +Y F  I  +   G
Sbjct: 364 VPLYLLFTPF----ILTTSAMFQGIGKGEKSLIISIFRSLICHISYAYLFAVILGLGMFG 419

Query: 423 I 423
           I
Sbjct: 420 I 420


>pir||A69905 conserved hypothetical protein yoeA - Bacillus subtilis
           >gi|2634220|emb|CAB13720.1| (Z99113) similar to
           hypothetical proteins from B. subtilis [Bacillus
           subtilis] >gi|2634231|emb|CAB13730.1| (Z99114) similar
           to hypothetical proteins from B. subtilis [Bacillus
           subtilis]
           Length = 463
           
 Score =  147 bits (367), Expect = 3e-34
 Identities = 96/404 (23%), Positives = 196/404 (47%), Gaps = 9/404 (2%)

Query: 28  PIVVNNLIQVLYNITDTFWLGK-LGREALSAPGVAWPIIGTLMALGMGFTMAGFSIVGQY 86
           P++++N++Q +  +     +G+ LG +A++A    +P+   L++  +G       ++GQ 
Sbjct: 28  PLLLSNVLQSVGQLVGMMAVGRWLGVDAVAAVSSFFPLFFLLISFTIGIGSGSSILIGQA 87

Query: 87  IGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRPYAYRYAIVIF 146
            GA + ++     G   +       + A+I  +     L  M    ++   +  YA ++F
Sbjct: 88  YGAKNEERLKAVVGTTLTFTFLLGVVLAVIGSIFTLDILRLMGTPENVIHVSANYARILF 147

Query: 147 AGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFI---FIF-KLGVLGAAL 202
             +P  FL+  +   +R TGD+KTP     ++  +NI L P+ I   F F KLG+ G+A 
Sbjct: 148 YAMPFMFLYFAYTTFLRGTGDSKTPFYTLIVSTVINIALLPVLILGMFGFPKLGIYGSAY 207

Query: 203 ATVLSNAVGTIIGVKILMSGKAGL---KITLEDLKPDWKFYSKIVRVGLPSSIGQSANSF 259
           ATV+S     ++ +  L   K  L   K     LK D +    ++R+G+P+SI     S 
Sbjct: 208 ATVISTIATFLVLMVYLRKRKHPLQFDKTVRRYLKMDKELLVLLLRLGVPASINMILVSL 267

Query: 260 GFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEKYERAKVI 319
             + +   +  +G    AAY +  ++ +++   +  + +A+    AQ++GA +++R K +
Sbjct: 268 SEIAVISFVNHYGSNATAAYGVVNQVASYVQMPAVSLGIAVSIFAAQSIGANEFDRLKQV 327

Query: 320 AERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISVPFFNGIFVV 379
               + +N+ I G  +++I VF   I  +FL + E +  +  +L   L S   F G   +
Sbjct: 328 IRVGIWLNYIIGGVLIILIYVFSHQILSLFLTEQESLYIAHRLLMTTLWSYLLF-GNAQI 386

Query: 380 VTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLGI 423
           ++    ++G  +   V+S+  +WG  +P+++   +   +  LG+
Sbjct: 387 ISATMRASGTVLWPTVISIFAIWGVEVPVAFVLSHYTKLEILGV 430


>gb|AAG20342.1| (AE005107) DNA damage-inducible protein; DinF [Halobacterium sp.
           NRC-1]
           Length = 469
           
 Score =  146 bits (365), Expect = 5e-34
 Identities = 123/461 (26%), Positives = 203/461 (43%), Gaps = 31/461 (6%)

Query: 10  RREILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLM 69
           R EI  G + + LL L  P+VV   + V+  I D FWLG++ R A+SA G+  P+IG L 
Sbjct: 6   RDEITGGSLPRALLVLTAPLVVQQYVVVVQQIVDVFWLGRVSRNAVSAVGLVAPLIGLLA 65

Query: 70  ALGMGFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMN 129
                 T+    +V Q++GA D   A RS G  F   +     + L+++++L LA D + 
Sbjct: 66  LATSVATIGCRVLVAQHVGADD-AAAARSTG--FHATVLVGAANLLLAVVVLWLAPDLVG 122

Query: 130 VTPS---IRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILD 186
           V  S   +      Y  V   G     +     +     GD++  + I+ + V  N++LD
Sbjct: 123 VLLSDEAVIQLGATYLTVTTVGRVFGGMSDTIESGFVGWGDSRMSMLINVVAVLTNVVLD 182

Query: 187 PIFIFIFKL------GVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFY 240
           P  +  ++L      G+ GAALAT +    G  + V  L        I   DL       
Sbjct: 183 PFLVVGWQLPGFAGYGIFGAALATAIGYVAGFTVAVAGLGVDSTSFTIGRADLGVSRDTV 242

Query: 241 SKIVRVGLPSSIGQSANSFGFVVLTRIIMGF-GDVTYAAYVITTRLVNFITSISRGISMA 299
             ++ VG+P +  ++      +++  I+ G  G    AAY I  R+       +  +  A
Sbjct: 243 RSLLSVGVPHAGQEAGRQIARLLVVAIVAGVAGSAGLAAYTIGARIATVAFVPAAAVGSA 302

Query: 300 MGTMVAQNVGAEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVP--IFKVFLDDPEVIA 357
           + ++V QNVGA   +RA       +      AG AVL +  +  P  I  VF      I 
Sbjct: 303 VSSIVGQNVGAGNPDRA--TRATWLAAGATTAGMAVLGVAQYSSPATIVSVFAPTFSGIE 360

Query: 358 ESKIVLEYFLISVPFFN-GIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIP 416
            +  V    +++V ++  G+   + G F+ AG T  SMV ++L+ WG R+P++    Y+ 
Sbjct: 361 LTYTVAYLQILAVGYWAFGLIYPIQGGFNGAGKTTVSMVATLLQYWGVRLPVAALGAYV- 419

Query: 417 AITFLGIRIPMAELFNFTSRGVFFGMGLSNFLAAIIGLAWF 457
                        +F+      F+ +  SN   A+   A+F
Sbjct: 420 ------------VVFSVPVHAAFWAITASNVACAVGVTAYF 448


>gi|11499066 conserved hypothetical protein [Archaeoglobus fulgidus]
           >gi|7451040|pir||F69433 conserved hypothetical protein
           AF1471 - Archaeoglobus fulgidus
           >gi|2649097|gb|AAB89777.1| (AE001001) conserved
           hypothetical protein [Archaeoglobus fulgidus]
           Length = 447
           
 Score =  145 bits (362), Expect = 1e-33
 Identities = 116/448 (25%), Positives = 206/448 (45%), Gaps = 23/448 (5%)

Query: 12  EILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMAL 71
           E+L G  +K +LKL+ P+VV+NLI  LYN+ D  W+  LG +ALSA G+ +PI    +A+
Sbjct: 5   EVLTGDPKKAILKLSAPMVVSNLIFTLYNLVDGIWVAGLGPDALSAVGLFFPIFFVFIAI 64

Query: 72  GMGFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVT 131
             G ++   S V + IGA  +  A  +A    ++ +  S +   +S++ L   + F+   
Sbjct: 65  SFGLSVGANSAVSRRIGAKRYDAACVAATLAVAMGILVS-IPMTLSVVFLNGVMVFLGAD 123

Query: 132 PSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF 191
             I   A  Y  ++  G        V   ++   G+ +  +  +A    LN++LDPIFI+
Sbjct: 124 GEILRLAVDYGSIMVLGSVFLVFSNVSAGILNGEGNARMAMYANAAGSLLNMVLDPIFIY 183

Query: 192 IFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPSS 251
           +   G+ GAA+A+V+S A+ +I+     +SG++ ++  +        F   ++RVG+P+S
Sbjct: 184 LLGYGIAGAAIASVISMALSSIVFSFWFLSGRSYVRFRVAGWNLPTVF--DLLRVGMPAS 241

Query: 252 IGQSANSFGFVVLTRIIMGF-GDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGA 310
           +     S  F+++ R+++   G    AAY    RL+ F      G+S A+  +     GA
Sbjct: 242 LSMLTMSVAFMLINRVVIETGGSEGLAAYTSAWRLIQFGFVPLFGVSAALTAVSGAAYGA 301

Query: 311 EKYERAKVIAERTMVVNFAI--AGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLI 368
               +       T+ +  A+  A  A++V    ++ +   + +   V+ E  +       
Sbjct: 302 RNPRKIGESLNYTVKLLLAVDAAILALMVAFAPQIALIFTYTEVSAVMYEEIVRTIRIAA 361

Query: 369 SVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLGIRIPMA 428
            V  F  + V  + VF   G   +S  +++LR   F++ L Y                +A
Sbjct: 362 FVLLFAPLGVSSSAVFQGMGKGERSFAITVLRAIVFQVSLCYV---------------LA 406

Query: 429 ELFNFTSRGVFFGMGLSNFLAAIIGLAW 456
             F F   GV  G  L   L    G +W
Sbjct: 407 VPFGFD--GVLLGFVLGEALGCFTGFSW 432


>emb|CAA84073.1| (Z34303) DinF protein [Streptococcus pneumoniae]
           Length = 456
           
 Score =  143 bits (357), Expect = 4e-33
 Identities = 104/396 (26%), Positives = 180/396 (45%), Gaps = 6/396 (1%)

Query: 12  EILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGK-LGREALSAPGVAWPIIGTLMA 70
           +++ GPI  +LL   +PI+++N+ Q LYN  D   +G+ LG+E+L+A G    I   ++ 
Sbjct: 8   DLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVGRFLGQESLAAVGATTAIFDLIVG 67

Query: 71  LGMGFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNV 130
             +G       ++ +Y GA +F K   +  A + L    S L  L+  L L   L +++ 
Sbjct: 68  FTLGVGNGMGIVIARYYGARNFTKIKEAVAATWILGALLSILVMLLGFLGLYPLLQYLDT 127

Query: 131 TPSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFI 190
              I P +Y+Y  +I   V VSF + +F  L+R+ GD+   +     +  +N++LD  FI
Sbjct: 128 PAEILPQSYQYISMIVTCVGVSFAYNLFAGLLRSIGDSLAALGFLIFSALVNVVLDLYFI 187

Query: 191 FIFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPS 250
               LGV  A LAT++S  +  ++    +      L    +  K D   Y+ ++  GL  
Sbjct: 188 TQLHLGVQSAGLATIISQGLSAVLCFYYIRKSVPELLPQFKHFKWDKSLYADLLEQGLAM 247

Query: 251 SIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGA 310
            +  S  S G V+L   +  FG V  +A     R++ F       IS +M T  +QN+GA
Sbjct: 248 GLMSSIVSIGSVILQFSVNTFGAVIISAQTAARRIMTFALLPMTAISASMTTFASQNLGA 307

Query: 311 EKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFL---DDPEVIAESKIVLEYFL 367
           ++ +R          ++ + A F V +   F  P    FL    D  +I    + L+   
Sbjct: 308 KRPDRIVQGLRIGSRLSISWAVF-VCIFLFFASPALVSFLASSTDGYLIENGSLYLQISS 366

Query: 368 ISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWG 403
              P  + + ++        G  +  +V S + L G
Sbjct: 367 TFYPILS-LLLIYRNCLQGLGQKILPLVSSFIELIG 401


>pir||C69140 conserved hypothetical protein MTH314 - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2621368|gb|AAB84820.1| (AE000816) conserved protein
           [Methanobacterium thermoautotrophicum]
           Length = 452
           
 Score =  133 bits (332), Expect = 4e-30
 Identities = 109/453 (24%), Positives = 204/453 (44%), Gaps = 29/453 (6%)

Query: 12  EILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMAL 71
           EI+ G   + L+KL+ P++V  L+  +YN+ D  W+  LG EAL+A G   PI   L+ L
Sbjct: 8   EIIRGDPRRALIKLSGPLIVAMLLTSIYNLVDAVWVAGLGGEALAAIGFVTPIYMILVGL 67

Query: 72  GMGFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVT 131
             G      S V + +GAGD +  N SA     + L  S +  +I  ++L   L  +   
Sbjct: 68  SNGLGAGAASSVSRCLGAGDEEGMNNSASHTIIITLAVSIILTVIIEILLRDILLSLGAA 127

Query: 132 PSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF 191
            +++P A  Y  V+FAG   +        ++R+ GD + P+    L+  LN++LDPI I+
Sbjct: 128 GALKP-AMEYGSVVFAGTLFTLFPGAAYGILRSEGDARRPMYAMGLSAVLNMVLDPILIY 186

Query: 192 IFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPSS 251
               G+ GAA ATV+S  + +++ +   ++G+    I     + D      I+ V +P+S
Sbjct: 187 TAGWGIAGAAWATVISQLLVSLLIIYWFLAGRTFTSIGWSHFRADRGVVWSILSVTIPAS 246

Query: 252 IGQSANSFGFVVLTRIIMGF-GDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGA 310
                 S    +L  I+    G    A Y    R+V         ++ A+ ++     G+
Sbjct: 247 AEFLVMSMVTALLNWILTSVAGTSAVAVYSAGWRIVMLAIVPVISVATALVSVSGVAYGS 306

Query: 311 EKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDD-------PEVIAESKIVL 363
             +E  +V    ++ +   IAG    +  V    I  +F          P +    +++ 
Sbjct: 307 RNFENLEVAHGYSIRLGLLIAGATAALTFVLAPWIAWIFSYSQASSHLAPRITGFLRVIC 366

Query: 364 EYFLISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLGI 423
            +++   P      ++   +F  AG  + S+++S++R    ++ L   F Y+ A+T    
Sbjct: 367 LFYIFLPP-----GIMSGSIFQGAGRGMTSLMLSVIR----QVLLVAVFAYLLAVT---- 413

Query: 424 RIPMAELFNFTSRGVFFGMGLSNFLAAIIGLAW 456
            + + E+      GV++G+   +   +++   W
Sbjct: 414 -LGLGEV------GVWWGVVAGDIGGSLVAYLW 439


>dbj|BAB06655.1| (AP001517) unknown conserved protein [Bacillus halodurans]
           Length = 452
           
 Score =  132 bits (329), Expect = 8e-30
 Identities = 103/412 (25%), Positives = 192/412 (46%), Gaps = 10/412 (2%)

Query: 21  TLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTMAGF 80
           TL  L WPI +  L+ +L    DT  L +   +A++A GV+  I+  ++ +  GF   G 
Sbjct: 10  TLFALTWPIFIEILLHMLMGNADTLMLSQYSDDAVAAVGVSNQILAVIIVM-FGFVATGT 68

Query: 81  SI-VGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRPYAY 139
           SI V Q++GA + + A + A       L F  +  L+ I   P  L  M +  S+   A 
Sbjct: 69  SILVAQHLGAKERENAGKVAVVSIGANLIFGIVLGLLLIAFGPPILKAMQLDDSLLQEAT 128

Query: 140 RYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF----IFKL 195
            Y  ++     V  L M   A++R+   TK  + ++     LN+I + +FIF    I  L
Sbjct: 129 LYLQIVGGFSVVQSLIMTAGAILRSHSFTKDVMYVTIGMNILNVIGNYLFIFGPFGIPVL 188

Query: 196 GVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYS--KIVRVGLPSSIG 253
           GV G AL+TV+S  +G  + + IL+  +   ++    L   +       ++++G+PS+  
Sbjct: 189 GVTGVALSTVVSRTIGLFV-IAILLYKRIRGELPFAYLLKRFPRVELRNLLKIGIPSAGE 247

Query: 254 QSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEKY 313
           Q + +   +V+T  I   G       V T  L+ F+   +  I      ++   VGA++ 
Sbjct: 248 QLSYNASQLVITYFIAMMGTEALTTKVYTQNLMMFVFLFAVAIGQGTQILIGHQVGAKQI 307

Query: 314 ERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISVPFF 373
           + A V   R++ +   ++    +V   F  P+  +F D+P++++    +L   +I  P  
Sbjct: 308 QAAYVRCFRSLWIAMTVSVSMAVVFFAFSTPLLGIFTDNPDILSLGTTLLLLTIILEP-G 366

Query: 374 NGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLGIRI 425
               +VV     +AG     + ++++ +WG  +P++Y  G    +  +G+ I
Sbjct: 367 RACNLVVISSLRAAGDVKFPVYLAIVSMWGIAVPIAYLLGLPLGLGLIGVWI 418


>pir||JC4561 DNA damage-inducible protein homolog - Pyrococcus sp
           >gi|971571|emb|CAA62487.1| (X91006) orf B [Pyrococcus
           sp.] >gi|1586540|prf||2204238A dinF-like gene
           [Pyrococcus sp.]
           Length = 363
           
 Score =  129 bits (321), Expect = 7e-29
 Identities = 90/314 (28%), Positives = 155/314 (48%), Gaps = 15/314 (4%)

Query: 18  IEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGV-----AWPIIGTLMALG 72
           I K L KLAWP +  N+ Q L N+ DT  +G +   AL    V     +W +   +MA+ 
Sbjct: 4   IRKRLWKLAWPAIAGNISQTLLNLVDTMIVGHVSAVALGCSWVWEGMVSWFMFPIMMAVS 63

Query: 73  MGFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTP 132
            G T+A   +V + +G  ++ +A+R A     +         L  I      L  M    
Sbjct: 64  TG-TLA---VVARRVGERNYDEASRVAEQSMYIAFILGIPVMLFGIFFGDDILRIMGAKG 119

Query: 133 SIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF- 191
            +   AY Y  V+F   P+ F+   F + +R  GDTKTP+ ++ L   +N +LD + +F 
Sbjct: 120 EVFEIAYAYLRVLFLFYPIRFVGFAFFSSLRGAGDTKTPMLLNILMNVVNAVLDYLLVFG 179

Query: 192 ---IFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGL 248
                ++G +GAA A+ +   +  ++G+ + ++ +  LK  LE L+  W    KI+R+G 
Sbjct: 180 KLGFPRMGPVGAAWASGIGITIAFLVGLYLFIAHRLVLKPVLE-LRIRWDIVEKILRIGT 238

Query: 249 PSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNV 308
           P+ + +   SF   +   I+  FG +  +A+ I  R+ +     + G S+A   +V Q++
Sbjct: 239 PTMLERGLFSFYNFLYMSIVTRFGKIALSAHHIGLRVESIAYMPAFGFSIATSALVGQSL 298

Query: 309 GAEKYE-RAKVIAE 321
           GA+K E R +V+ E
Sbjct: 299 GAKKPEQRGRVVKE 312


>pir||H69837 conserved hypothetical protein yisQ - Bacillus subtilis
           >gi|1934838|emb|CAB07959.1| (Z93940) unknown [Bacillus
           subtilis] >gi|2145382|emb|CAA70645.1| (Y09476) YisQ
           [Bacillus subtilis] >gi|2633417|emb|CAB12921.1| (Z99109)
           alternate gene name: yucE~similar to hypothetical
           proteins [Bacillus subtilis]
           Length = 455
           
 Score =  126 bits (314), Expect = 5e-28
 Identities = 101/431 (23%), Positives = 205/431 (47%), Gaps = 15/431 (3%)

Query: 5   KVKAMRREILEGPIEKT--LLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAW 62
           K    +   L+ P +KT  L  L WPI +   + +     DT  L +    +++A GV+ 
Sbjct: 2   KQAVFKSTALKKPADKTFSLFSLTWPIFIEVSLYMFMGNADTLMLSQYSDNSVAAVGVSN 61

Query: 63  PIIGTLMALGMGFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFS-TLSALISILIL 121
            I+  ++ +          I+ Q++G+   K+A   A        F S  +SA++    +
Sbjct: 62  QILNLIIVMFSFIATGTTVIISQFLGSRQKKEAMEVAYVSIGANFFISLAISAVVFFAAV 121

Query: 122 PLALDFMNVTPSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFL 181
           PL L  M ++ ++ P A  +  V+     +  L M F+A++++ G TK  + ++     L
Sbjct: 122 PL-LHMMGLSDALMPDAKVFLQVVGGLSFIQALIMTFSAILKSYGYTKDTMFVTIGMNIL 180

Query: 182 NIILDPIFIF-IF---KLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDW 237
           NI  + + IF +F    LGV G A++T ++  +G +I + ++++ +  LK++L+ +    
Sbjct: 181 NIAGNFVVIFGLFGFPVLGVAGVAMSTSIARVIG-LIAMIVIVNKRIQLKMSLKKVFHMH 239

Query: 238 KFY-SKIVRVGLPSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGI 296
           K +  K++++G+PS+  Q + +   +++T  I   G       V T  +  FI      I
Sbjct: 240 KEHLRKLLKIGIPSAGEQLSYNLSQMIVTYFIAIMGAQALTTKVYTQNITMFILLFGTAI 299

Query: 297 SMAMGTMVAQNVGAEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVI 356
           S     ++ + +G ++++ A     +++     IA    +++ +F   +  +F   P++I
Sbjct: 300 SQGTQILIGRYIGGKQFDAAYERCMKSLYWALGIAAATSVLMTIFSKDLIGLFTQSPDII 359

Query: 357 AESKIVLEYFLISVP--FFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGY 414
           A + +++   +I  P   FN   V++     +AG     + M+M+ +WG  +PL+Y FG 
Sbjct: 360 ATASLLIAMTIILEPGRSFN---VIIINSLRAAGDAKFPVYMAMISMWGIGLPLAYLFGI 416

Query: 415 IPAITFLGIRI 425
                  GI I
Sbjct: 417 HLGFGLAGIWI 427


>pir||G82392 conserved hypothetical protein VCA0989 [imported] - Vibrio cholerae
           (group O1 strain N16961) >gi|9658430|gb|AAF96885.1|
           (AE004425) conserved hypothetical protein [Vibrio
           cholerae]
           Length = 444
           
 Score =  125 bits (312), Expect = 8e-28
 Identities = 104/452 (23%), Positives = 202/452 (44%), Gaps = 28/452 (6%)

Query: 18  IEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTM 77
           + K L ++ WP++   L  + + + D+ ++G+LG   L+A G   PI   ++ + +G  +
Sbjct: 10  LAKQLFQMTWPMLFGVLSLMSFQLVDSAFIGQLGVLPLAAQGFTMPIQMVIIGIQVGLGI 69

Query: 78  AGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRPY 137
           A  +++ + IGAG  + A +  G +  +      L AL+  L+    L  +    ++   
Sbjct: 70  ATTAVISRAIGAGKTEYAKQLGGLVIVIGGIGVALIALVLYLLRQPLLGLLGAPETVFAI 129

Query: 138 AYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIFIFKLGV 197
              Y +   A      +   + ++ RA G+T  P  +  +T  LN+ILDPIFIF F LG+
Sbjct: 130 IDHYWLWWLASAWTGAMLYFYYSVCRANGNTLLPGTLMMVTSVLNLILDPIFIFTFDLGI 189

Query: 198 LGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPSSIGQSAN 257
            GAA+AT+++  VG  I V   ++ +       +DL    +  + +  +  P+ + Q   
Sbjct: 190 DGAAIATIIAFGVGIAI-VAPKVAQRQWTSYQWQDLNIS-QSLTALGHIMGPAMLSQLLP 247

Query: 258 SFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEKYERAK 317
               +  T+++  FG    AA+ + +R   F       ++M++  M+ + +GA++    +
Sbjct: 248 PLSSMFATKLLASFGTAAVAAWALGSRFEFFALVAVLAMTMSLPPMIGRMLGAKEITHIR 307

Query: 318 VIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISVPF---FN 374
            +                LV  VF  P+ ++   + EV      +L   L+ VP      
Sbjct: 308 QLVRIACQFVLGFQLLIALVTYVFATPLAELMTSETEV----SQILNLHLVIVPISLGAL 363

Query: 375 GIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLGIRIPMAELFNFT 434
           GI +++  V ++ G +  ++ +S LRL+ F +P  +   +     F GI           
Sbjct: 364 GICMLMVSVANALGKSYVALTISALRLFAFYLPCLWLGAH-----FYGI----------- 407

Query: 435 SRGVFFGMGLSNFLAAIIGLAWFLKGSWMRRI 466
             G+F G  + N +A     AW      +R++
Sbjct: 408 -EGLFIGALVGNIIAG--WAAWLAYQKALRQL 436


>pir||E82296 conserved hypothetical protein VC0650 [imported] - Vibrio cholerae
           (group O1 strain N16961) >gi|9655087|gb|AAF93816.1|
           (AE004151) conserved hypothetical protein [Vibrio
           cholerae]
           Length = 445
           
 Score =  116 bits (289), Expect = 4e-25
 Identities = 100/430 (23%), Positives = 196/430 (45%), Gaps = 17/430 (3%)

Query: 18  IEKTLLKLAWPIVVNNLIQVLYNITDTFWLGK-LGREALSAPGVAWPIIGTLMALGM--G 74
           I +  ++   P V   L+  LY + D  ++G  +G E L+   VAWP+IGT++ +GM  G
Sbjct: 6   IYRQFVRYTIPTVAAMLVNGLYQVVDGIFIGHYVGAEGLAGINVAWPVIGTILGIGMLVG 65

Query: 75  FTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMN---VT 131
                 + + Q  G  D  K   + G L SL+L    L+ ++++++  +A DF+      
Sbjct: 66  VGTGALASIKQGEGHPDSAKRILATG-LMSLLL----LAPIVAVILWFMADDFLRWQGAE 120

Query: 132 PSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF 191
             +     +Y  V+  G   +   +    L+R          +  +    NI LD +FI 
Sbjct: 121 GRVFELGLQYLQVLIVGCLFTLGSIAMPFLLRNDHSPNLATLLMVIGALTNIALDYLFIA 180

Query: 192 IFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPSS 251
             +  + GAA+AT L+  V T++G+    S +A +++T   L+ +W    KI  +G+ S 
Sbjct: 181 WLQWELTGAAIATTLAQVVVTLLGLAYFFSARANMRLTRRCLRLEWHSLPKIFAIGVSSF 240

Query: 252 IGQSANSFGFVVLTRIIMGFGD-VTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGA 310
              +  S    +   +++ +G+ V   AY +   +V        GI+  M  + + + GA
Sbjct: 241 FMYAYGSTMVALHNTLMIEYGNAVMVGAYAVMGYIVTIYYLTVEGIANGMQPLASYHFGA 300

Query: 311 EKYERAKVIAERTMVVNFAIAGFA-VLVIGVFRVPIFKVF-LDDPEVIAESKIVLEYFLI 368
             Y+  + +    M +   + G A VLV+ +F      +F   D E+IA +++ ++  L 
Sbjct: 301 RNYDHIRKLLRLAMGI-AVLGGMAFVLVLNLFPEQAIAIFNSSDSELIAGAQMGIKLHLF 359

Query: 369 SVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLGIRIPMA 428
           ++ + +G  VV    + S     K+M +++  +    +P  +       +T + I +P++
Sbjct: 360 AM-YLDGFLVVSAAYYQSTNRGGKAMFITVGNM-SIMLPFLFILPQFFGLTGVWIALPIS 417

Query: 429 ELFNFTSRGV 438
            +   T  G+
Sbjct: 418 NIVLSTVVGI 427


>gb|AAG20494.1| (AE005121) DNA damage-inducible protein; Dip1 [Halobacterium sp.
           NRC-1]
           Length = 513
           
 Score =  116 bits (288), Expect = 5e-25
 Identities = 102/391 (26%), Positives = 173/391 (44%), Gaps = 8/391 (2%)

Query: 25  LAWPIVVNNLIQVLYNITDTFWLG-KLGREALSAPGVAWPIIGTLMALGMGFTMAGFSIV 83
           LA P +V   ++ L    D F +    G  A++A  + +        L +  T    S+V
Sbjct: 35  LAVPAMVTGGLRTLLRTADFFMVSIATGSTAVAALEIGFQYYFIPFGLALALTSGTISVV 94

Query: 84  GQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRPYAYRYAI 143
            ++ GA D   AN +      L L  S      + +     +  +N  P I      Y  
Sbjct: 95  SRFKGADDHAGANFAIKQSLWLALLVSLPITAGTWVYADSMIGLLNSNPEIIELGAAYLR 154

Query: 144 VIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF---IF-KLGVLG 199
           V+   V   F  M  +  +   GDT+TP+ +  +T+  NI L+ + IF   +F +LGV+G
Sbjct: 155 VVMLTVVFRFWGMTASRALAGAGDTRTPMYVRLITLPTNIALNAVLIFGIWVFPELGVVG 214

Query: 200 AALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPSSIGQSANSF 259
           AA  T ++NAV  I+   +L+SG+  + ++    + DW   S+IVRV LP +  + + +F
Sbjct: 215 AAWGTAIANAVAGIVFFAVLLSGRWDVTLSFSGKQWDWGVASEIVRVSLPLAGTRLSRTF 274

Query: 260 GFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEKYERAKVI 319
           G      ++  F     AAY I  R++      + G S A  T+V Q +GA   + A   
Sbjct: 275 GRFPFLFVLGLFSHQVVAAYAIGRRVMLLALMPAWGYSTASSTLVGQQLGAGDPDEAAAY 334

Query: 320 AERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISVPFFNGIFVV 379
             +T+ V  A       ++ V   PI   F   PE  + +   +  F +SV  F+ +   
Sbjct: 335 GWQTLRVALATQLIIGALLFVAAGPIASAF--TPERFSLTVTFIRIFGLSVAGFS-VART 391

Query: 380 VTGVFSSAGHTVKSMVMSMLRLWGFRIPLSY 410
           + G    AG T   +   ++  +  R+PL++
Sbjct: 392 LRGALRGAGDTRWPLYGGLIGTYIVRLPLAF 422


>pir||G64614 conserved hypothetical integral membrane protein HP0759 -
           Helicobacter pylori (strain 26695)
           >gi|2313885|gb|AAD07807.1| (AE000588) conserved
           hypothetical integral membrane protein [Helicobacter
           pylori 26695]
           Length = 417
           
 Score =  113 bits (280), Expect = 4e-24
 Identities = 101/429 (23%), Positives = 180/429 (41%), Gaps = 34/429 (7%)

Query: 45  FWLGKLGREALSAPGVAWPIIGTLMALGMGFTMAGFSIVGQYIGAGDFKKANRSAGALFS 104
           F++GK+    + A GV    +     +         +I+ + +GA DF + N +  ++F 
Sbjct: 9   FFVGKISHHHIVALGVGLQFLMLFYGINTILYTGTNAILSRLVGARDFTQINHAFSSIFI 68

Query: 105 LVLFFSTLSALISILILPLALDFMNVTPSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRA 164
                      +S  ++   L++M +    R     Y  V+   +P  FL  +  + + +
Sbjct: 69  GAFMICLGVLFVSYFLIEPFLNWMQLQDPSRQLTQDYLEVLVVALPSIFLKNILVSALAS 128

Query: 165 TGDTKTPVKISALTVFLNIILDPIFIF----IFKLGVLGAALATVLSN-----AVGTIIG 215
             DT TP  +  + V   I L+   IF      ++G++G+ALA V+ +     A+G  I 
Sbjct: 129 FSDTLTPFIVKIIMVIACIFLNQALIFGDFGFKEMGIVGSALANVVVSYLELLALGVWIQ 188

Query: 216 VKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPSSIGQSANSFGFVVLTRIIMGFGDVT 275
           +K +       KIT       + F   + RVG P+   +  + F  ++L++ +  +GD  
Sbjct: 189 IKKI---PLKFKITFH-----FSFLKTMFRVGWPAGFERLLSLFSLILLSKFVASYGDKV 240

Query: 276 YAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEKYERAKVIAERTMVVNFAIAGFAV 335
            A   I  R+  F      G  +A   +  QN+GA K + A   A   + ++  + G   
Sbjct: 241 LAGMQIGIRVETFSFMPGFGFMIAAMVLTGQNLGANKPKIATEYAHLILKISMGLMGVLG 300

Query: 336 LVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISVPFFNGIFVVVTGVFSSAGHTVKSMV 395
           +V+ +F      +F  D EV+  ++  L    +S     G F V+ GVF  AG +  S+ 
Sbjct: 301 IVLVLFAKEFASLFSQDEEVLEVARSYLIAVGLSQAPLIGYF-VLDGVFRGAGISKVSLY 359

Query: 396 MSMLRLWGFRIPLSYAFGYIPAITFLGIRIPMAELFNFTSRGVFFGMGLSNFLAAIIGLA 455
           ++ L LWG RI                + I +  + +F    +F  +    FL + I   
Sbjct: 360 INTLSLWGLRI----------------MPIYLLLIHHFKVEFIFVVIASETFLRSFIYYK 403

Query: 456 WFLKGSWMR 464
            F KG W R
Sbjct: 404 VFSKGIWKR 412


>pir||E70312 conserved hypothetical protein aq_128 - Aquifex aeolicus
           >gi|2982882|gb|AAC06502.1| (AE000675) hypothetical
           protein [Aquifex aeolicus]
           Length = 472
           
 Score =  112 bits (278), Expect = 8e-24
 Identities = 105/403 (26%), Positives = 178/403 (44%), Gaps = 26/403 (6%)

Query: 20  KTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTMAG 79
           K ++KL+ PI+V NL+  + N+     +  +   A++A G +  ++  + +L M  + +G
Sbjct: 17  KKVVKLSIPIIVVNLLYTVENMISMILVSSISPSAVAATGFSLSLLWFIYSL-MALSYSG 75

Query: 80  FSI-VGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDF-------MNVT 131
            +I + Q++GA    K + S   +  L L F     LIS+ +     DF       +  +
Sbjct: 76  TNILIAQFVGA----KKDPSPILINGLFLSF-----LISLPLFFYGKDFVLFLMKVLGAS 126

Query: 132 PSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF 191
            ++R  A  Y   IF  +P+ FL   F       GDTKTP+K++ +    +I      I 
Sbjct: 127 ETVRSLAKEYLTPIFWFIPIGFLTNTFYGAYNGAGDTKTPMKVAIIMNLTHIGTAYTLIN 186

Query: 192 ----IFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVG 247
               + KLGV GA     +S  +   I   +L+  K    + L  L+P  K   K+VR+G
Sbjct: 187 GKFGLPKLGVEGAGWGIAISEILAFFIYTFLLIFFKKPFPLHLR-LEP--KLLFKMVRLG 243

Query: 248 LPSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQN 307
            P+++ ++  +  F V    +  FGD   AA+ I  R+ +    I  G+ +A  T+  QN
Sbjct: 244 TPTALERAITTLSFNVFVGFLAKFGDKVLAAHQIGLRIESISFMIGFGVMIASTTLAGQN 303

Query: 308 VGAEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFL 367
            GA  Y         +      +     L++ +F   +   F  DPEVI  +   L+   
Sbjct: 304 YGARNYRGMVHAVNTSAHFTALVMSLTGLILILFPHYLVYPFSRDPEVIEWASYYLQIVG 363

Query: 368 ISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSY 410
           IS P       + +G     G T   + +++   W FRI  SY
Sbjct: 364 ISQPAM-AYASIYSGALKGMGKTHIPLFVNISSFWLFRIIPSY 405


>pir||H71898 hypothetical protein jhp0696 - Helicobacter pylori (strain J99)
           >gi|4155262|gb|AAD06282.1| (AE001501) putative
           [Helicobacter pylori J99]
           Length = 417
           
 Score =  110 bits (273), Expect = 3e-23
 Identities = 103/431 (23%), Positives = 185/431 (42%), Gaps = 38/431 (8%)

Query: 45  FWLGKLGREALSAPGVAWPIIGTLMALGMGFTMAGFSIVGQYIGAGDFKKANRSAGALF- 103
           F++GK+    + A GV    +     +         +I+ + +GA DF + N +  ++F 
Sbjct: 9   FFVGKISHHHIVALGVGLQFLMLFYGINTILYTGTNAILSRLVGARDFAQINHAFSSIFI 68

Query: 104 -SLVLFFSTLSALISILILPLALDFMNVTPSIRPYAYRYAIVIFAGVPVSFLFMVFNALM 162
            + V+    L A  S  ++   L++M +    R     Y  V+   +P  FL  V  + +
Sbjct: 69  GAFVICLGVLFA--SYFLIEPFLNWMQLQDPSRQLTQDYLEVLVIALPSIFLKNVLVSAL 126

Query: 163 RATGDTKTPVKISALTVFLNIILDPIFIF----IFKLGVLGAALATVLSN-----AVGTI 213
            +  DT TP  +  + V   I L+   IF      ++G++G+ALA V+ +     A+   
Sbjct: 127 ASFSDTLTPFIVKIIMVIACIFLNQALIFGDFGFKEMGIVGSALANVVVSYWELLALSLW 186

Query: 214 IGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPSSIGQSANSFGFVVLTRIIMGFGD 273
           I +K +       KIT       + F   + +VG P+   +  + F  ++L++ +  +GD
Sbjct: 187 IQIKKI---PLKFKITFH-----FSFLKTMFKVGWPAGFERLLSLFSLILLSKFVASYGD 238

Query: 274 VTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEKYERAKVIAERTMVVNFAIAGF 333
              A   I  R+  F      G  +A   +  QN+GA K + A   A   + ++  + G 
Sbjct: 239 KVLAGMQIGIRVETFSFMPGFGFMIAAMVLTGQNLGANKPKIATEYAHLILKISMGLMGV 298

Query: 334 AVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISVPFFNGIFVVVTGVFSSAGHTVKS 393
             +++ +F      +F  D EV+  ++  L    +S     G F V+ GVF  AG +  S
Sbjct: 299 LGVILILFAKEFASLFSQDGEVLEVARSYLIAVGLSQAPLIGYF-VLDGVFRGAGISKVS 357

Query: 394 MVMSMLRLWGFRIPLSYAFGYIPAITFLGIRIPMAELFNFTSRGVFFGMGLSNFLAAIIG 453
           + ++ L LWG RI                + I +  +++F    +F  + L  FL + I 
Sbjct: 358 LYINTLSLWGLRI----------------MPIYLLLIYHFKVEFIFVVIALETFLRSFIY 401

Query: 454 LAWFLKGSWMR 464
              F KG W R
Sbjct: 402 YKVFSKGIWKR 412


>pir||G70172 conserved hypothetical integral membrane protein BB0584 - Lyme
           disease spirochete >gi|2688513|gb|AAB91523.1| (AE001160)
           conserved hypothetical integral membrane protein
           [Borrelia burgdorferi]
           Length = 448
           
 Score =  109 bits (269), Expect = 9e-23
 Identities = 113/455 (24%), Positives = 195/455 (42%), Gaps = 28/455 (6%)

Query: 18  IEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTM 77
           I K LLK+A P  +   +    ++TD   +  LG   ++   +A       + +G  F+M
Sbjct: 16  IYKDLLKIAIPTAIEFFLFNFISLTDNAMVAYLGDYPVAGVSLANKFFELFVTIG--FSM 73

Query: 78  AG-FSIVG--QYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSI 134
           AG ++I+   QY   GDFK    +       ++ FS    LISI+     L  ++     
Sbjct: 74  AGAYNIIATRQY-NQGDFKSFRNTFFISILTIILFSFPFILISIVNPFFLLRLISNDERA 132

Query: 135 RPYAYRYA-IVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIFIF 193
             Y   Y  I IF+ V      ++ NAL +     K  V IS  +V LN + + IFIF+F
Sbjct: 133 VYYGAAYLNIAIFSFVFAIIKGLIANAL-KVVEIVKFQVYISVFSVLLNFVFNYIFIFVF 191

Query: 194 KLGVLGAALATVLSNAVGTIIGVKILMSGKAG-LKITLEDLKPDWKFYSKIVRVGLPSSI 252
            +GV+GAA+AT +   +  I+ +      K   L   L+DL  + K ++++++  +P  +
Sbjct: 192 HMGVVGAAIATTVIRTLELIVYLVCTAFNKNSILHFKLDDLNINIKPFAQLIKFFIPILL 251

Query: 253 GQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEK 312
            + A  FG++VLT I +G     YAAY I+  +   I +I     +++  M+   +   K
Sbjct: 252 NEFAWFFGYLVLTSIFIGIDTHKYAAYSISFSIYFIIFNIIHSFCISLNIMMGYEMHNSK 311

Query: 313 YERAKVIAERTMV-VNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISVP 371
            E  KV    + + +  A     VL I  F  P     L    +I    I+L Y  +S  
Sbjct: 312 KEIMKVAIYLSKIGLKLAFLTSFVLFIFSFFAPYIFYTLKYSHLIG---IILRYSSVSAF 368

Query: 372 FFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLGIRIPMAELF 431
           F    F  + G F +        +M     + + IP+++                +A   
Sbjct: 369 FMALAFQYLFGFFRAGASPSFGAIMEGSVTFVYTIPIAFV---------------LANYT 413

Query: 432 NFTSRGVFFGMGLSNFLAAIIGLAWFLKGSWMRRI 466
           N     + F   L + +  ++ L +F    W++ +
Sbjct: 414 NLPFEIIVFIPSLEDAIKLVVSLPYFYSERWIKSV 448


>sp|P45272|YDHE_HAEIN HYPOTHETICAL PROTEIN HI1612 >gi|1074865|pir||B64173 hypothetical
           protein HI1612 - Haemophilus influenzae (strain Rd KW20)
           >gi|1574453|gb|AAC23256.1| (U32834) conserved
           hypothetical transmembrane protein [Haemophilus
           influenzae Rd]
           Length = 464
           
 Score =  106 bits (263), Expect = 4e-22
 Identities = 95/401 (23%), Positives = 172/401 (42%), Gaps = 9/401 (2%)

Query: 20  KTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTMAG 79
           K L+K++ PI++  + Q    + DT   G++    ++A  +   I   LM  G G  +A 
Sbjct: 14  KKLIKISLPILLAQIAQNSMGLADTIMAGRVSSTDMAAISIGASIWMPLMFFGQGLLLAL 73

Query: 80  FSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRPYAY 139
              +    G+G   +          LVL  S    L+ I    + L +M +   +   A 
Sbjct: 74  PPTISYLNGSGQHHRIAHQVRQGIWLVLGVSIPLGLL-IYFCEIPLQYMQMESKMSDLAR 132

Query: 140 RYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF----IFKL 195
            Y   +  G+P   + + F  L      TK  + I+ L + +NI L+ IFI+    +   
Sbjct: 133 DYLHAMLWGLPAYLMLINFRCLNDGIEKTKPAMVITFLGLLINIPLNYIFIYGKFGMPAF 192

Query: 196 GVLGAALATVLSNAVGTIIGV--KILMSGKAGLKITLEDLK-PDWKFYSKIVRVGLPSSI 252
           G +G  +AT + N    ++ +      + +  LK+  + ++ P+ K   K++R+GLP +I
Sbjct: 193 GAVGCGIATAIVNWAMCLMMIFYSYTNTQERSLKVFSQLIEMPNPKTLKKLLRLGLPIAI 252

Query: 253 GQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEK 312
                   + + + ++   G    A++ IT    +FI      I MA   +V Q +GA  
Sbjct: 253 AICCEVALYALTSLMLSPLGATIVASHQITLNTSSFIFMFPMSIGMATTILVGQALGAGS 312

Query: 313 YERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISVPF 372
            + AK I    +++   +     L+   FR  I  +F+ D  VIA +  +L  F     F
Sbjct: 313 PQNAKKIGYAALLLGLTVTIVTALITIFFRYEIASIFVTDEIVIAMAANLL-LFAALYQF 371

Query: 373 FNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFG 413
            + I +VV G+      T   + +++   W   +PL Y  G
Sbjct: 372 SDTIQMVVGGILRGYKDTKVILYITLFSYWVIGVPLGYTLG 412


>pir||H64667 conserved hypothetical integral membrane protein HP1184 -
           Helicobacter pylori (strain 26695)
           >gi|2314344|gb|AAD08230.1| (AE000624) conserved
           hypothetical integral membrane protein [Helicobacter
           pylori 26695]
           Length = 459
           
 Score =  104 bits (256), Expect = 3e-21
 Identities = 108/451 (23%), Positives = 197/451 (42%), Gaps = 56/451 (12%)

Query: 12  EILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGK-LGREALSAPGVAWPIIGTLMA 70
           ++ + PI K       P+  + +    Y++ D  ++GK LG+EA++A  +AWPI   L+A
Sbjct: 7   DLHKDPIRKLFFYYFIPLAFSMISLSTYSMIDGMFVGKKLGKEAIAAVNIAWPIFPGLIA 66

Query: 71  LGMGFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSA-LISILILPLA---LD 126
             + F     SIVG ++G    +     A  +FS V +F  +SA ++S+ +LP +     
Sbjct: 67  YELLFGFGAASIVGYFLG----QNKTHRARLVFSSVFYFVAISAFILSMALLPFSETIAR 122

Query: 127 FMNVTPSIRPYAYRYAIVIFAGVPVSFLFMVFNAL--MRATGDTKTPVKISALTV--FLN 182
           F     ++   + RY  +I  G     +FMV + L  +    D +  + + A+ +    N
Sbjct: 123 FFGSNDALLSMSKRYIEIILMGA----VFMVLHPLADVFVVNDKRPILAMVAMLIGSLAN 178

Query: 183 IILDPIFIFIFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSK 242
           I  + +FIF+ K+GV G+A+ATV+ +A+G ++ ++     K  L           +F   
Sbjct: 179 IFFNYLFIFVLKVGVQGSAIATVIGHAIGVLVLMQHFWRKKGQLYFIK-------RFSLS 231

Query: 243 IVRVGLPSSIGQSANSFGFVVL-------------TRIIMGFGDVTYAAYVITTRLVNFI 289
            V     S + QS   F   V+              R +  +G V Y A +  T L    
Sbjct: 232 SVISSAKSGVPQSTAEFSASVMILLFNTAIMHTAGERFVSMYGIVMYNAIIFFTTLF--- 288

Query: 290 TSISRGISMAMGTMVAQNVGAEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVP---IF 346
            +IS+GI      + + + GA   ER K +    +   F I    ++  G +      + 
Sbjct: 289 -AISQGIQ----PIASFSYGARNLERVKEVFVFGLKAAFCI---GIVFYGAYYFLDEFLI 340

Query: 347 KVFL----DDPEVIAESKIVLEYFLISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLW 402
           K++L     DP  + E+K  +  + +    F G+ ++    F S   T  S ++++    
Sbjct: 341 KLYLQPSEQDPLFMQETKRAMNIYYVGY-IFLGMTLLCAVFFQSIQRTKSSFIITLSHTL 399

Query: 403 GFRIPLSYAFGYIPAITFLGIRIPMAELFNF 433
           GF + L     +   I  + +  P+A+   F
Sbjct: 400 GFIVILLPILSHFYGINGVWVTYPIAQFLAF 430


>dbj|BAA15804.1| (D90837) ORF_ID:o347#5~similar to [SwissProt Accession Number
           P45272] [Escherichia coli]
           Length = 546
           
 Score =  101 bits (249), Expect = 2e-20
 Identities = 91/421 (21%), Positives = 184/421 (43%), Gaps = 18/421 (4%)

Query: 20  KTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTMAG 79
           + +  LA PI + N   +L  +  TF +  LG++A++  G+A      +MA      +  
Sbjct: 91  REITPLAVPIFMENACVLLMGVLSTFLVSWLGKDAMAGVGLADSFNMVIMAFFAAIDLGT 150

Query: 80  FSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFM--NVTPSIRPY 137
             +V   +G  D ++A  +      ++  F+ L A +        +DF+  + T  ++  
Sbjct: 151 TVVVAFSLGKRDRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAGDATTEVKAL 210

Query: 138 AYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF-IFK-- 194
           A  Y  +     P + + ++ +  +R  G+TK P+ I+     LNII+  I I+ +F   
Sbjct: 211 ALTYLELTVLSYPAAAITLIGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSWP 270

Query: 195 -LGVLGAALATVLSNAVGTIIGVKILMSG-KAGLKITLED-LKP-DWKFYSKIVRVGLPS 250
            LG +GA L   +S  +G +  + +L  G    L+I+L+   KP ++    +++ +G+P+
Sbjct: 271 GLGFVGAGLGLTISRYIGAVAILWVLAIGFNPALRISLKSYFKPLNFSIIWEVMGIGIPA 330

Query: 251 SIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGA 310
           S+     + G ++    + G G    A   I   +   I      +  A   +  + +G 
Sbjct: 331 SVESVLFTSGRLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGSALGSASTIITGRRLGV 390

Query: 311 EKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKV----FLDDPEVIAESKIVLEYF 366
            +  +A++         F ++   +  I     P   V    +  DP+V     I++   
Sbjct: 391 GQIAQAEIQLRHV----FWLSTLGLTAIAWLTAPFAGVMASFYTQDPQVKHVVVILIWLN 446

Query: 367 LISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLGIRIP 426
            + +P ++  +V+  G F  A     +M +SML +WG R+ + Y  G +     +G+ + 
Sbjct: 447 ALFMPIWSASWVLPAG-FKGARDARYAMWVSMLSMWGCRVVVGYVLGIMLGWGVVGVWMG 505

Query: 427 M 427
           M
Sbjct: 506 M 506


>sp|P76352|YEEO_ECOLI HYPOTHETICAL 60.1 KDA PROTEIN IN AMN-CBL INTERGENIC REGION
           >gi|7466643|pir||B64963 membrane protein yeeO -
           Escherichia coli >gi|2367126|gb|AAC75048.1| (AE000290)
           orf, hypothetical protein [Escherichia coli K12]
           Length = 547
           
 Score =  101 bits (249), Expect = 2e-20
 Identities = 91/421 (21%), Positives = 184/421 (43%), Gaps = 18/421 (4%)

Query: 20  KTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTMAG 79
           + +  LA PI + N   +L  +  TF +  LG++A++  G+A      +MA      +  
Sbjct: 92  REITPLAVPIFMENACVLLMGVLSTFLVSWLGKDAMAGVGLADSFNMVIMAFFAAIDLGT 151

Query: 80  FSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFM--NVTPSIRPY 137
             +V   +G  D ++A  +      ++  F+ L A +        +DF+  + T  ++  
Sbjct: 152 TVVVAFSLGKRDRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAGDATTEVKAL 211

Query: 138 AYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF-IFK-- 194
           A  Y  +     P + + ++ +  +R  G+TK P+ I+     LNII+  I I+ +F   
Sbjct: 212 ALTYLELTVLSYPAAAITLIGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSWP 271

Query: 195 -LGVLGAALATVLSNAVGTIIGVKILMSG-KAGLKITLED-LKP-DWKFYSKIVRVGLPS 250
            LG +GA L   +S  +G +  + +L  G    L+I+L+   KP ++    +++ +G+P+
Sbjct: 272 GLGFVGAGLGLTISRYIGAVAILWVLAIGFNPALRISLKSYFKPLNFSIIWEVMGIGIPA 331

Query: 251 SIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGA 310
           S+     + G ++    + G G    A   I   +   I      +  A   +  + +G 
Sbjct: 332 SVESVLFTSGRLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGSALGSASTIITGRRLGV 391

Query: 311 EKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKV----FLDDPEVIAESKIVLEYF 366
            +  +A++         F ++   +  I     P   V    +  DP+V     I++   
Sbjct: 392 GQIAQAEIQLRHV----FWLSTLGLTAIAWLTAPFAGVMASFYTQDPQVKHVVVILIWLN 447

Query: 367 LISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLGIRIP 426
            + +P ++  +V+  G F  A     +M +SML +WG R+ + Y  G +     +G+ + 
Sbjct: 448 ALFMPIWSASWVLPAG-FKGARDARYAMWVSMLSMWGCRVVVGYVLGIMLGWGVVGVWMG 506

Query: 427 M 427
           M
Sbjct: 507 M 507


>gb|AAG10466.1|AF279106_28 (AF279106) predicted cation efflux pump [uncultured proteobacterium
           EBAC31A08]
           Length = 448
           
 Score =  101 bits (249), Expect = 2e-20
 Identities = 92/369 (24%), Positives = 167/369 (44%), Gaps = 35/369 (9%)

Query: 12  EILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMAL 71
           + L+ PI   L+K++ P  V  LI  +  + + +++ +LG   L+A  +A+P I  ++  
Sbjct: 7   QFLKDPIFPLLIKMSAPNTVAFLINAVVVLAEFWFISQLGITPLAAVTLAFPAI--MLTQ 64

Query: 72  GMGFTMAGFSI---VGQYIGAGDFKKANRSA---------GALFSLVLFFSTLSALISIL 119
            M F   G ++   + + +GA D  +A +           GAL  L++FF     L+ IL
Sbjct: 65  QMAFGALGGAVTSSIARSLGAADKPRAEKLLWHSLYISCFGALAFLIIFFIFGEPLLRIL 124

Query: 120 ILPLALDFMNVTPSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTV 179
                      T ++   +  Y  V   G  V +L     A +R  GD + P  ++ +  
Sbjct: 125 ---------GGTGALLEESLAYCFVYLLGAIVVWLSGSLTAALRGMGDMQFPAVLTVICA 175

Query: 180 FLNIILDPIFIF----IFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKP 235
            + +     FI     + KLG++G+A + ++++    ++ +  + S  + +++ L+ L  
Sbjct: 176 GIQVFFSAGFILGSFGLPKLGLVGSAWSMIVTSGFMALVTLIKISSPSSPVRLKLKRLTI 235

Query: 236 DWKFYSKIVRVGLPSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRG 295
           + + +  I  V LP+S+         ++LT +I  FG    A Y I +R+   +  I  G
Sbjct: 236 ERELFEDIFSVALPASLSPIMTVATVLLLTGLIGQFGTSAIAGYGIGSRVEFLLIPIVFG 295

Query: 296 ISMAMGTMVAQNVGAEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPI----FKVFLD 351
           I  AM  MV  N+GA+  ER    AE+  +V    AG    VIG+           +F  
Sbjct: 296 IGTAMTAMVGTNIGAKNIER----AEKIGMVGATTAGLLSAVIGLALALTPNLWISIFTS 351

Query: 352 DPEVIAESK 360
           DPE +  +K
Sbjct: 352 DPETLLVTK 360


>pir||A71849 hypothetical protein jhp1110 - Helicobacter pylori (strain J99)
           >gi|4155699|gb|AAD06682.1| (AE001538) putative
           [Helicobacter pylori J99]
           Length = 459
           
 Score =  101 bits (248), Expect = 3e-20
 Identities = 102/432 (23%), Positives = 193/432 (44%), Gaps = 50/432 (11%)

Query: 28  PIVVNNLIQVLYNITDTFWLGK-LGREALSAPGVAWPIIGTLMALGMGFTMAGFSIVGQY 86
           P+V + +    Y++ D  ++GK LG+EA++A  +AWPI   L+A  + F     SIVG +
Sbjct: 23  PLVFSMISLSTYSMVDGMFVGKKLGKEAIAAVNIAWPIFPGLIAYELLFGFGAASIVGYF 82

Query: 87  IGAGDFKKANRSAGALFSLVLFFSTLSA-LISILILPLALD---FMNVTPSIRPYAYRYA 142
           +G    +     A  +FS V +F  LSA ++S+ +LP + +   F     ++   + RY 
Sbjct: 83  LG----QNKTHRARLVFSSVFYFVALSAFILSMALLPFSENIARFFGSNDALLSMSKRYI 138

Query: 143 IVIFAGVPVSFLFMVFNAL--MRATGDTKTPVKISALTV--FLNIILDPIFIFIFKLGVL 198
            +I  G     +FMV + L  +    D +  + + A+ +    NI  + +FIF+ ++GV 
Sbjct: 139 EIILMG----SVFMVLHPLADVFVVNDKRPVLAMVAMLIGSLANIFFNYLFIFVLEVGVQ 194

Query: 199 GAALATVLSNAVGTIIGVKILMSGKAGL----KITLEDLKPDWKFYSKIVRVGLPSSIGQ 254
           G+A+ATV+ +A+G ++ ++     K  L    + +L  +           + G+P S  +
Sbjct: 195 GSAIATVIGHAIGVLVLMQHFWRKKGQLYFIKRFSLSSV-------ISSAKSGVPQSTAE 247

Query: 255 SANSFGFVVLTRIIMG---------FGDVTYAAYVITTRLVNFITSISRGISMAMGTMVA 305
            + S   ++    IM          +G V Y A +  T L     +IS+GI      + +
Sbjct: 248 FSASIMILLFNTAIMHTAGERFVSMYGIVMYNAIIFFTTLF----AISQGIQ----PIAS 299

Query: 306 QNVGAEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPE----VIAESKI 361
            + GA   ER + +    +   F I  F           + K++L   E     + E+K 
Sbjct: 300 FSYGARNLERVRAVFVFGLKAAFCIGIFFYGAYYFLDEFLIKLYLQPSEQDALFMQETKR 359

Query: 362 VLEYFLISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFL 421
            +  + +   F  G+ ++    F S   T  S ++++    GF + L     +   +  +
Sbjct: 360 AMNIYYVGYVFL-GMTLLCAVFFQSIQRTKSSFIITISHTLGFIVILLPILSHFYGVNGI 418

Query: 422 GIRIPMAELFNF 433
            +  P+A+   F
Sbjct: 419 WVTYPIAQFLAF 430


>pir||E82175 conserved hypothetical protein VC1631 [imported] - Vibrio cholerae
           (group O1 strain N16961) >gi|9656143|gb|AAF94782.1|
           (AE004241) conserved hypothetical protein [Vibrio
           cholerae]
           Length = 458
           
 Score =  100 bits (247), Expect = 3e-20
 Identities = 98/409 (23%), Positives = 172/409 (41%), Gaps = 19/409 (4%)

Query: 14  LEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGM 73
           + G   + L+ +A PI + N++     + D   LG+LG   ++A GVA         + +
Sbjct: 11  MRGDFFRRLIAIALPITLQNIMFSSRGLVDVLMLGQLGEAEIAAVGVAARATFVTTIMLV 70

Query: 74  GFTMAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISIL----ILPLALDFMN 129
           G T  G  +  QY GAGD K    S    + +  FF+  + L+ +     I+ L  D   
Sbjct: 71  GVTTGGALLTAQYWGAGDRKGVRESTALTWLVSNFFAFFTVLLFLFFPQQIMSLTTDSEQ 130

Query: 130 VTPSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIF 189
           V      Y    +  +FA   VS + +   A+ +    T      S + +  N++L+ I 
Sbjct: 131 VNALGSQYLIITSFTMFAVACVSSMAVGLRAMHKPGVSTF----FSGIGIVSNVVLNWIL 186

Query: 190 IF----IFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKP--DWKFYSKI 243
           IF       +G+ GAA+ATVLS A+        L   K  +    +D+K   DW   S+ 
Sbjct: 187 IFGKFGFPAMGIQGAAIATVLSGAIEIACLYSYLYGKKHLMAFGWQDIKAVIDWPKISRF 246

Query: 244 VRVGLPSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTM 303
           +R+ LP++      + G      I+   G    AA  + T + +   S+  G+S A   +
Sbjct: 247 LRLSLPTTFNFLIWAAGLFTYHAIMGQTGVQGLAALSVMTPVESISLSLLIGMSTAAAVL 306

Query: 304 VAQNVGAEKYERAKVIAERTMVVNFAIAGFAVLVIGVF--RVPIFKVFLD-DPEVIAESK 360
           V   +GA+ YE   V  +   V   ++    V+ IG++  ++P+   F    PE    S+
Sbjct: 307 VGNQLGAKNYE--AVYYQAIGVTACSVLVGIVVAIGLYLVQIPVLGAFTALTPETRELSE 364

Query: 361 IVLEYFLISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLS 409
             +    + +   +     + GV  + G     +   ++  W   IPL+
Sbjct: 365 KFMLILCLGIVLRSFPMTAIVGVLRAGGDVKFCLGQDIVAQWCIGIPLA 413


>pir||C72561 hypothetical protein APE1773 - Aeropyrum pernix (strain K1)
           >gi|5105463|dbj|BAA80776.1| (AP000062) 423aa long
           hypothetical protein [Aeropyrum pernix]
           Length = 423
           
 Score = 99.5 bits (244), Expect = 7e-20
 Identities = 101/382 (26%), Positives = 170/382 (44%), Gaps = 28/382 (7%)

Query: 41  ITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTMAGFSIVGQYIGAGDFKKANRSAG 100
           I DT+++G LG E+++A G A  +I   M       M    I+GQ IG+G+     R+AG
Sbjct: 12  IVDTYFVGGLGSESIAAVGAAGYLIWLYMVFSTLVYMGVLVILGQAIGSGNRGLVERAAG 71

Query: 101 ALFSLVLFFSTLSALISILILPLALD-----FMNVTPSIRPYAYRYAIVIFAGVPVSFLF 155
                     TLS L+SI++   A        + + P +   A+ Y  V    V + ++ 
Sbjct: 72  EGL-------TLSILLSIIVCAAAFAASKQLLVVLAPEVDQLAWEYLSVSLLTVALHYVT 124

Query: 156 MVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF----IFKLGVLGAALATVLSNAVG 211
           ++++A+ RA G T   +  S +    N  LDPI I+       LGV GAA A+V      
Sbjct: 125 ILYDAVFRALGKTMPILYSSGVFTLANTALDPILIYGRLGAPALGVEGAAWASV----AA 180

Query: 212 TIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPSSIGQSANSFGFVVLTRIIMGF 271
           +++G+ +L+     L + L  L+P       I+ +G PS + +     G VV    +   
Sbjct: 181 SLLGLLVLVYLSRYLDVGLRPLRPT-SVSRSILALGFPSMVERVVFVVGNVVYLGSVSRC 239

Query: 272 GDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEKYERAKVIAERTMVVNFAI- 330
           G    AA+ I  R+ +        I+ A G MV   VGA +   +K      + ++  I 
Sbjct: 240 GADALAAHTIGVRIESLAFLPLFSIATASGVMVGWEVGAGRIAESKSTGWELIKLSSLIG 299

Query: 331 --AGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISVPFFNGIFVVVTGVFSSAG 388
              G A+ + G    PI   F  DP V   + + L    ++ P   G+ +V   +  +AG
Sbjct: 300 LVVGAALALGGWLVTPI---FTGDPRVAWLAALYLVIAGLTEPLL-GVVMVAGQIIRNAG 355

Query: 389 HTVKSMVMSMLRLWGFRIPLSY 410
            T    ++++  L+  R+  +Y
Sbjct: 356 DTRTPTLVNLGSLYILRVVPAY 377


>pir||H81402 probable integral membrane protein Cj0560 [imported] -
           Campylobacter jejuni (strain NCTC 11168)
           >gi|6968028|emb|CAB75196.1| (AL139075) putative integral
           membrane protein [Campylobacter jejuni]
           Length = 442
           
 Score = 99.1 bits (243), Expect = 1e-19
 Identities = 103/446 (23%), Positives = 186/446 (41%), Gaps = 29/446 (6%)

Query: 20  KTLLKLAWPIVVNNLIQVLYNITDTFWLGK-LGREALSAPGVAWPIIGTLMALGMGFTMA 78
           +  +K A P V++      Y I D  ++GK LG +AL+A  +  P I    AL     + 
Sbjct: 12  RLFVKYAVPNVISMAFISFYYIVDGIFVGKYLGSDALAALALIIPFIMMSFALADMIAIG 71

Query: 79  GFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRPYA 138
               +  ++G G    A +   +   ++   S    ++   + P+ +D +NV+  I+   
Sbjct: 72  SAVQISMHLGLGKKNLARKIFSSSMLIIFIISCFIGILEYFLGPVLIDCLNVSDEIKTMT 131

Query: 139 YRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIFIFKLGVL 198
                V     P + L    +  +R  G T   + ++ +    NI+LD IFI     G+ 
Sbjct: 132 KECMFVFALFAPFTMLSFALDNYLRICGKTAYSMVMNVIIALSNIVLDYIFIVELGWGLF 191

Query: 199 GAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPSSIGQSANS 258
            AALAT L   +G I G+   +     LKI+   L  + K +  I+  G     G  + S
Sbjct: 192 SAALATCLGLVLGGIFGIFPFLFQNLELKIS--SLYMNLKIFKNILYNGSSEFFGNISGS 249

Query: 259 FGFVVLTRIIMGFGDV-TYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEKYERAK 317
              +    +++   D    AA+ I   + +FI  +   I  AM   ++ N   + + R K
Sbjct: 250 LYSIFANFVLLKISDTQAVAAFSIVLYIDSFIIMLIIAIGDAMQPALSYNYAKKDFSRIK 309

Query: 318 VIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISVPFFNGIF 377
            I +        ++ F++++I +F   +  +F  +     ++       L +  +F   F
Sbjct: 310 AIIKVVFFAGGFLSLFSIVLILIFGENLITLFTKENNQEFKTFAYTALMLFAFNYFFAWF 369

Query: 378 VVVTGVFSSAGHTVK-SMVMSMLRLWGFRIPLSYAFGYIPAITFLGIRIPMAELFNFTSR 436
            V++G F +A +    S+V+S+ +     IPL   F  +    F+G+             
Sbjct: 370 NVLSGSFLTAFNKASFSLVLSLAQ--NLFIPL---FFLLFLSCFMGLN------------ 412

Query: 437 GVFFGMGLSNFLA--AIIGLAW-FLK 459
               G+ LS F A   ++ LAW FLK
Sbjct: 413 ----GVWLSPFFAEFCVLILAWIFLK 434


>dbj|BAB07764.1| (AP001520) unknown conserved protein in others [Bacillus
           halodurans]
           Length = 447
           
 Score = 98.7 bits (242), Expect = 1e-19
 Identities = 102/425 (24%), Positives = 190/425 (44%), Gaps = 23/425 (5%)

Query: 21  TLLKLAWPIVVNNLIQVLYNITDTFWLGK-LGREALSAPGVAWPIIGTLMALGMGFTMAG 79
           TLL  A P +   L   +Y + D  ++ + +G  ALSA  + +PI G ++A+ +      
Sbjct: 15  TLLAYAAPTMALMLFMSIYTMVDGMFIARYVGATALSAVNIFFPIYGLIIAIALMLGTGA 74

Query: 80  FSIVGQYIGAGDFKKANRS------AGALFSLVLFFSTLSALISILILPLALDFMNVTPS 133
            +I+ + IG  + ++A  +       GA+  LV+    L  +  IL++  A      T  
Sbjct: 75  NAIIAKKIGENNEEEAKENFTFIVICGAVLGLVITVFGLLLMEPILLMLGA----GATEE 130

Query: 134 IRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIFIF 193
           +  + Y YA +I    P   L M+F       G     + I+ +    NI+LD +FI + 
Sbjct: 131 LFDFTYTYAKIILCTSPFMILQMLFQNFFVTAGKPNLGLTITVVGGVANIVLDYVFIVLL 190

Query: 194 KLGVLGAALATVLSNAVGTIIG-VKILMSGKAGLKITLEDLKPDWKFYSKIVRVG---LP 249
           ++G+ GA +AT +   +    G V  + + ++GL       K D K        G   + 
Sbjct: 191 QMGIAGAGIATAIGIFIPAAYGFVYFIYNKESGLHFVKP--KVDGKVLLNSCINGSSEMV 248

Query: 250 SSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVG 309
           S++  S  +F F +L  +I   G    AA  I   ++  ++SIS G S  +  +++ N G
Sbjct: 249 SNLASSIVTFAFNLL--MIKHLGVDGVAAITIMLYVMFILSSISMGYSAGVAPIISYNYG 306

Query: 310 AEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYF-LI 368
           ++   + K +   ++++   I    +  + +     F  F+  PE  A   I +E   + 
Sbjct: 307 SKNSSQLKRVFNYSLLI-IVIGSVTMYGVSMMFGAYFIQFM-APEGSAVYHIAIEGLNIF 364

Query: 369 SVPF-FNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLGIRIPM 427
           S+ F F G  +  + VF++  +   S  +S LR   F +   +    I  +T + + IP+
Sbjct: 365 SISFLFMGFNIFSSMVFTAFSNGKISAAISFLRTLVFVLASLWILPAILGVTGIWLAIPL 424

Query: 428 AELFN 432
           AE+ +
Sbjct: 425 AEILS 429


>gb|AAG19201.1| (AE005016) DNA damage-inducible protein; Dip2 [Halobacterium sp.
           NRC-1]
           Length = 489
           
 Score = 97.5 bits (239), Expect = 3e-19
 Identities = 113/463 (24%), Positives = 178/463 (38%), Gaps = 57/463 (12%)

Query: 24  KLAWPIVVNNLIQVLYNITDTFWLGK-LGREALSAPGVAWPIIGTLMALGMGFTMAGFSI 82
           +LAWP ++  + ++  +  D   +G  LG  A++  G A P  G   ++G G      ++
Sbjct: 47  ELAWPRILTGIGRMSKSAADVAMVGAALGSAAITGVGYAGPFWGAAFSIGGGLAAGTIAL 106

Query: 83  VGQYIGAGDFKKANRS---------AGALFSLVLFFSTLSALISILILPLALDFMNVTPS 133
           V Q   A +   A ++         A  L   VLF+S  +ALI +L             +
Sbjct: 107 VSQRFSADEIADAGQALRSSAALTVAATLPIAVLFYSHPAALIGLL---------TDRQA 157

Query: 134 IRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIFIF 193
              +   Y  V+  GVP + L ++ +  +    D  T + +       NI L+ +FIF  
Sbjct: 158 EIAFGADYLRVVAFGVPFAGLNLIGSRALIGADDAYTAMVLRGGGALANIGLNGVFIFGL 217

Query: 194 KLGVLGAALATVLSNAVGTIIGVKILMSGK----AGLKITLEDLKPDWKFYS--KIVRVG 247
             GV+GA L TVLSN V T   V  L  G+        +T+      W       IV +G
Sbjct: 218 GWGVVGAGLGTVLSNVVVTTAFVVGLSRGRLPAVGAFPMTVSVRGAYWVRDDCWDIVTIG 277

Query: 248 LPSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQN 307
           LP     S  +     L   +  FG    AAY+I  R+   + +   G  +A  ++V Q 
Sbjct: 278 LPVVGRNSVWTLARFPLLAFMSLFGQPVAAAYIIVRRVFGIMNTPGWGFGLAASSLVGQE 337

Query: 308 VG------AEKYERAKVIAERTMVVNFA--IAGFAVLVIGVFRVPIFKVFLDDPEVIAES 359
           +G      A  Y R   +    M V FA  +  FA  ++GV     F     DP V    
Sbjct: 338 LGQGRESTAAAYGREITLYSVVMYVMFAGVVCAFAGQIVGV-----FVDSASDPSV--PI 390

Query: 360 KIVLEYFLISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAIT 419
            + + Y   +     GI   V G   + G T           W F        G +P + 
Sbjct: 391 AVTMVYVAAAAVIPQGIGATVAGALDATGDT----------RWPFYSRAVGMLGALP-LV 439

Query: 420 FLGIRIPMAELFNFTSRGVFFGMGLSNFLAAIIGLAWFLKGSW 462
           +LG   P+         G++  +     + A++    F  G W
Sbjct: 440 YLGATTPLG------LYGIYLSLFSETCVPAVVNYLRFRSGKW 476


>pir||F69906 conserved hypothetical protein yojI - Bacillus subtilis
           >gi|2634337|emb|CAB13836.1| (Z99114) similar to
           hypothetical proteins [Bacillus subtilis]
           >gi|3169325|gb|AAC17857.1| (AF026147) YojI [Bacillus
           subtilis]
           Length = 452
           
 Score = 95.6 bits (234), Expect = 1e-18
 Identities = 94/435 (21%), Positives = 183/435 (41%), Gaps = 23/435 (5%)

Query: 20  KTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVA---WPIIGTLMALGMGFT 76
           K LL +  PI +      L    DT   GK+    L+   +    W  + T +A   G  
Sbjct: 12  KQLLHILIPIFITQAGLSLITFLDTVMSGKVSPADLAGVAIGSSLWTPVYTGLA---GIL 68

Query: 77  MAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRP 136
           MA   IV Q +GA   +K   +      +    S    +I    + L L  +N+   +  
Sbjct: 69  MAVTPIVAQLLGAEKKQKIPFTVLQAVYVAALLSIAVLVIGYAAVDLILGRLNLDIHVHQ 128

Query: 137 YAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF----I 192
            A  +   +  G+   F++ V  + + + G T+  + I+  ++ +N +L+ +FIF    +
Sbjct: 129 IAKHFLGFLSLGIFPLFVYTVLRSFIDSLGKTRVTMMITLSSLPINFVLNYVFIFGKFGM 188

Query: 193 FKLGVLGAALATVLSNAVGTIIGVKILMSG----KAGLKITLEDLKPDWKFYSKIVRVGL 248
             LG +GA LA+ L+     II   I+       + G+ +T+   K  WK    ++++GL
Sbjct: 189 PALGGVGAGLASALTYWCICIISFFIIHKNAPFSEYGIFLTM--YKFSWKACKNLLKIGL 246

Query: 249 PSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNV 308
           P        +  F  +T ++  F  VT A++       + +  +   +SMA+  +V    
Sbjct: 247 PIGFAVFFETSIFAAVTLLMSHFHTVTIASHQAAMNFASLLYMLPLSVSMALTIVVGFEA 306

Query: 309 GAEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLI 368
           GA +++ A+  +   +++    + F    I +FR  I  ++  DP+V+     + ++FLI
Sbjct: 307 GAARFKDARSYSLIGIMMAIGFSLFTAACILLFREQIAGMYTSDPDVLR----LTQHFLI 362

Query: 369 SVPFF---NGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLGIRI 425
              FF   + +   + G          ++  + +  W   +P+ Y  G   ++   G  I
Sbjct: 363 YALFFQLSDAVAAPIQGALRGYKDVNYTLAAAFVSYWVIGLPVGYMVGTFTSLGAFGYWI 422

Query: 426 PMAELFNFTSRGVFF 440
            +       + G+FF
Sbjct: 423 GLIAGLAAGAVGLFF 437


>dbj|BAA31456.1| (AB010463) NorM [Vibrio parahaemolyticus]
           Length = 456
           
 Score = 93.2 bits (228), Expect = 6e-18
 Identities = 83/401 (20%), Positives = 164/401 (40%), Gaps = 12/401 (2%)

Query: 21  TLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTMAGF 80
           +L+KLA P+++ ++ Q      DT   G + +  ++A  VA  I    +  G+G  MA  
Sbjct: 10  SLIKLATPVLIASVAQTGMGFVDTVMAGGVTQTDMAAVSVASSIWLPSILFGIGLLMALV 69

Query: 81  SIVGQYIGAGDFKKA--NRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRPYA 138
            +V Q  G+   +K       G + +L++    +  L+    +   L  M+V   +    
Sbjct: 70  PVVAQLNGSARREKIPFEIQQGVVLALLISIPIIGVLLQTQFI---LQLMDVEAVMADKT 126

Query: 139 YRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF----IFK 194
             Y   +   VP   LF    +       TK  + I  + + LNI L+ IF++      +
Sbjct: 127 VGYIHAVIFAVPAFLLFQTLRSFTDGMSLTKPAMVIGFIGLLLNIPLNWIFVYGKFGAPE 186

Query: 195 LGVLGAALATVLSNAV--GTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPSSI 252
           LG +G  +AT +   V    ++   +  S    + +  E  KP WK   ++ ++G P + 
Sbjct: 187 LGGVGCGVATTIVYWVMFALLLAYVMTSSRLKSINVFGEYHKPQWKAQVRLFKLGFPVAA 246

Query: 253 GQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEK 312
                   F V+  ++   G +  AA+ +     + +  +   +  A+   V   +G E 
Sbjct: 247 ALFFEVTLFAVVALLVSPLGPIIVAAHQVAINFSSLVFMLPMSVGAAVSIRVGHRLGEEN 306

Query: 313 YERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISVPF 372
            + A+V +   ++V  A+A    ++  + R  I +++ ++PEVI  +  +L  F      
Sbjct: 307 VDGARVASRVGIMVGLALATITAIITVLSRELIAELYTNNPEVITLAMQLL-LFAAVYQC 365

Query: 373 FNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFG 413
            + + V+  G              + +  W   +P  Y  G
Sbjct: 366 TDAVQVIAAGALRGYKDMRAIFNRTFIAYWILGLPTGYILG 406


>pir||T36597 hypothetical protein SCH24.32c - Streptomyces coelicolor
           >gi|4808406|emb|CAB42738.1| (AL049826) hypothetical
           protein [Streptomyces coelicolor A3(2)]
           Length = 448
           
 Score = 91.3 bits (223), Expect = 2e-17
 Identities = 73/370 (19%), Positives = 159/370 (42%), Gaps = 4/370 (1%)

Query: 19  EKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTMA 78
           ++ ++ LA P     + + L+ + D+  +G LG   L+  G+A  ++ T +++ +    A
Sbjct: 19  DREIVALAVPAFGALVAEPLFVMADSAIVGHLGTAQLAGLGIASALLTTAVSVFVFLAYA 78

Query: 79  GFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRPYA 138
             + V + +GAG+ + A R       L L        + +   P  ++    + +  PYA
Sbjct: 79  TTAAVSRRVGAGNLQAAIRQGMDGIWLALLLGAAVVAVFLPAAPSLVELFGASDTAAPYA 138

Query: 139 YRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIFIFKLGVL 198
             Y  +   G+P   + +    ++R   +T+TP+ ++      N +L+ + ++   LG+ 
Sbjct: 139 TTYLRISSLGIPAMLVVLASTGVLRGLQNTRTPLYVAVAGFIANAVLNVLLVYGAGLGIA 198

Query: 199 GAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPSSIGQSANS 258
           G+A  TV++      + + +++    G +     L+PD        + G+P  +   +  
Sbjct: 199 GSAWGTVIAQCGMAAVYLWVVV---RGARQHGASLRPDLVGIRASAQAGMPLLVRTLSLR 255

Query: 259 FGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEKYERAKV 318
              ++ T +    GD   AA+ I   L + +      I++A   ++ + +GA+  + A+ 
Sbjct: 256 AILMIATAVAARLGDADIAAHQIVLSLWSLLAFALDAIAIAGQAIIGRYLGADDAQGARE 315

Query: 319 IAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISVPFFNGIFV 378
              R +    A+     L++ + R     +F  D  V   +   L    ++ P   G+  
Sbjct: 316 ACRRMVEWGVAVGVVLGLLVVLSRPVFLPLFTGDSMVTDAALPALVIVAVAQPVC-GVVF 374

Query: 379 VVTGVFSSAG 388
           V+ GV   AG
Sbjct: 375 VLDGVLMGAG 384


>gb|AAF21214.1|AC013483_38 (AC013483) putative integral membrane protein [Arabidopsis
           thaliana] >gi|11128377|gb|AAG31183.1|AC074395_4
           (AC074395) MATE efflux family protein, putative
           [Arabidopsis thaliana]
           Length = 526
           
 Score = 90.9 bits (222), Expect = 3e-17
 Identities = 79/309 (25%), Positives = 138/309 (44%), Gaps = 13/309 (4%)

Query: 93  KKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPS---IRPYAYRYAIVIFAGV 149
           K+  R+A     L L    + A+  I    L L  M V P+   + P A++Y  +   G 
Sbjct: 165 KRTIRTASTAMILGLILGLVQAIFLIFSSKLLLGVMGVKPNSPMLSP-AHKYLSIRALGA 223

Query: 150 PVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIFIFKLGVLGAALATVLSNA 209
           P   L +    + R   DTKTP+  + +   +NI+LDPIFIF+ +LG++GAA+A V+S  
Sbjct: 224 PALLLSLAMQGIFRGFKDTKTPLFATVVADVINIVLDPIFIFVLRLGIIGAAIAHVISQY 283

Query: 210 VGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPSSIGQSANSFGFVVLTRIIM 269
             T+I    L      +     DL+     + + ++ GL       A +F   +   +  
Sbjct: 284 FMTLILFVFLAKKVNLIPPNFGDLQ-----FGRFLKNGLLLLARTIAVTFCQTLAAAMAA 338

Query: 270 GFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEKYERAKVIAERTMVVNFA 329
             G    AA+ I  ++    + ++ G+++A   ++A +   + Y +   +A R + + F 
Sbjct: 339 RLGTTPMAAFQICLQVWLTSSLLNDGLAVAGQAILACSFAEKDYNKVTAVASRVLQMGFV 398

Query: 330 IAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISVPFFNGIFVVVTGV---FSS 386
           +     + +G+       VF  DP VI    I + +   + P  N +  V+ GV    S 
Sbjct: 399 LGLGLSVFVGLGLYFGAGVFSKDPAVIHLMAIGIPFIAATQP-INSLAFVLDGVNFGASD 457

Query: 387 AGHTVKSMV 395
             +T  SMV
Sbjct: 458 FAYTAYSMV 466


>pir||C81156 conserved hypothetical protein NMB0812 [imported] - Neisseria
           meningitidis (group B strain MD58)
           >gi|7226046|gb|AAF41225.1| (AE002434) conserved
           hypothetical protein [Neisseria meningitidis MC58]
           Length = 459
           
 Score = 90.9 bits (222), Expect = 3e-17
 Identities = 85/405 (20%), Positives = 174/405 (41%), Gaps = 15/405 (3%)

Query: 20  KTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTMAG 79
           + L  LA P+++  + QV     DT   G  G+E L+A  +      T+    MG   A 
Sbjct: 18  RLLTTLALPMLLAQVAQVGIGFVDTVMAGGAGKEDLAAVALGSSAFATVYITFMGIMAAL 77

Query: 80  FSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRPYAY 139
             ++ Q  GAG   +   +        LF      ++    +    +++ ++  +     
Sbjct: 78  NPMIAQLYGAGKTDEVGETGRQGIWFGLFLGVFGMVLMWAAITPFRNWLTLSDYVEGTMA 137

Query: 140 RYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF-IFKLGVL 198
           +Y +     +P + +    +A   +    +  + +S     LN+ L+ IF++  F +  L
Sbjct: 138 QYMLFTSLAMPAAMVHRALHAYTSSLNRPRLIMLVSFAAFVLNVPLNYIFVYGKFGMPAL 197

Query: 199 GAALATVLSNAVG--TIIGVKILMSGKAGLK---ITLEDLKPDWKFYSKIVRVGLPSSIG 253
           G A   + + AV   + + + I ++ +   +   +T +  KPDW  + +I ++G P  + 
Sbjct: 198 GGAGCGLATMAVFWFSALALWIYIAKENFFRPFGLTAKFGKPDWAVFKQIWKIGAPIGLS 257

Query: 254 Q--SANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAE 311
               A++F F+V   +I  FG+   AA  +   L   +  I + +  A    +  ++G  
Sbjct: 258 YFLEASAFSFIVF--LIAPFGEDYVAAQQVGISLSGILYMIPQSVGSAGTVRIGFSLGRR 315

Query: 312 KYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISVP 371
           ++ RA+ I+  ++V+ + +A   VL + +FR P+  ++ +DP V++ +  VL   L +  
Sbjct: 316 EFSRARYISGVSLVLGWMLAVITVLSLVLFRSPLVSMYNNDPAVLSIAATVL---LFAGL 372

Query: 372 FFNGIFVVVTGVFSSAGHTVKS--MVMSMLRLWGFRIPLSYAFGY 414
           F    F      ++  G+ V    M +     WG  +   Y   Y
Sbjct: 373 FQPADFTQCIASYALRGYKVTKVPMFIHAAAFWGCGLLPGYLLAY 417


>pir||D81950 probable transmembrane efflux protein NMA1022 [imported] -
           Neisseria meningitidis (group A strain Z2491)
           >gi|7379724|emb|CAB84291.1| (AL162754) putative
           transmembrane efflux protein [Neisseria meningitidis
           Z2491]
           Length = 459
           
 Score = 89.7 bits (219), Expect = 6e-17
 Identities = 85/405 (20%), Positives = 173/405 (41%), Gaps = 15/405 (3%)

Query: 20  KTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTMAG 79
           + L  LA P+++  + QV     DT   G  G+E L+A  +      T+    MG   A 
Sbjct: 18  RLLTALALPMLLAQVAQVGIGFVDTVMAGGAGKEDLAAVALGSSAFATVYITFMGIMAAL 77

Query: 80  FSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRPYAY 139
             ++ Q  GAG   +   +        LF      ++    +    +++ ++  +     
Sbjct: 78  NPMIAQLYGAGKTDEVGETGRQGIWFGLFLGVFGMVLMWAAITPFRNWLTLSDYVEGTMA 137

Query: 140 RYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF-IFKLGVL 198
           +Y +     +P + +    +A   +    +  + +S     LN+ L+ IF++  F +  L
Sbjct: 138 QYMLFTSLAMPAAMVHRALHAYASSLNRPRLIMLVSFAAFVLNVPLNYIFVYGKFGMPAL 197

Query: 199 GAALATVLSNAVG--TIIGVKILMSGKAGLK---ITLEDLKPDWKFYSKIVRVGLPSSIG 253
           G A   + + AV   + + + I ++ +   +   +T +  KPDW  + +I ++G P  + 
Sbjct: 198 GGAGCGLATMAVFWFSALALWIYIAKENFFRPFGLTAKFGKPDWAVFKQIWKIGAPIGLS 257

Query: 254 Q--SANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAE 311
               A++F F+V   +I  FG+   AA  +   L   +  I + +  A    +  ++G  
Sbjct: 258 YFLEASAFSFIVF--LIAPFGEDYVAAQQVGISLSGILYMIPQSVGSAGTVRIGFSLGRR 315

Query: 312 KYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISVP 371
           ++ RA+ I+  ++V  + +A   VL + +FR P+  ++ +DP V++ +  VL   L +  
Sbjct: 316 EFSRARYISGVSLVSGWMLAVITVLSLVLFRSPLVSMYNNDPAVLSIAATVL---LFAGL 372

Query: 372 FFNGIFVVVTGVFSSAGHTVKS--MVMSMLRLWGFRIPLSYAFGY 414
           F    F      ++  G+ V    M +     WG  +   Y   Y
Sbjct: 373 FQPADFTQCIASYALRGYKVTKVPMFIHAAAFWGCGLLPGYLLAY 417


>dbj|BAB04579.1| (AP001510) unknown conserved protein [Bacillus halodurans]
           Length = 458
           
 Score = 88.5 bits (216), Expect = 1e-16
 Identities = 104/459 (22%), Positives = 191/459 (40%), Gaps = 49/459 (10%)

Query: 20  KTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTMAG 79
           K  L +  PI++  +     N  DT   G+ G   L+   +   +   +     G  +A 
Sbjct: 12  KLFLVVMMPILITQIGLYAMNFFDTVMSGQAGANDLAGVAIGSSLWVPVFTGLNGVLLAL 71

Query: 80  FSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALD----FMNVTPSIR 135
             I+ Q IGA    +       +F   L+ S   ++  ILI  + LD     M++   + 
Sbjct: 72  TPIIAQSIGA----EKRDDVPYVFLQGLYLSIAISIAVILIGAVVLDPILSAMSLEDEVG 127

Query: 136 PYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF---- 191
             A  Y I +  G+   F++     L+ + G+T+  + I+ L++ +NI  + + IF    
Sbjct: 128 RIAKEYLIGLAFGIVPLFIYTTIRCLIDSLGETRVTMFITLLSLPINIFFNYVLIFGKLG 187

Query: 192 IFKLGVLGAALAT------VLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVR 245
             +LG +GA  A+      +L+ A+  ++ V+     +   K+    LK  WK   +I+ 
Sbjct: 188 FPRLGGVGAGYASAITYWFILAVAIVVVVKVRPFTDFQLFKKLYHVSLKK-WK---EILL 243

Query: 246 VGLPSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVA 305
           +GLP        +  F  +T ++  F   T AA+       +F+  I   I+  +   V 
Sbjct: 244 LGLPIGFTIFFETSIFAAVTLLMSTFDTATIAAHQAAVNFASFLYMIPLSIAFTLTIAVG 303

Query: 306 QNVGAEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEY 365
             VGA++ E A+  +   +     +   A ++I V R P+  ++ +D +V      +++ 
Sbjct: 304 YEVGAKRVEDARQYSRLGITFALIMGLVAGVIIYVLRAPVASLYTNDSQV----AWLIQQ 359

Query: 366 FLISVPFF---NGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLG 422
           FLI   FF   + +   + GV           VM+++  W   +P  Y            
Sbjct: 360 FLIYSIFFQLSDALATPIQGVLRGHKDVNVPFVMALVSFWIIGLPTGYL----------- 408

Query: 423 IRIPMAELFNFTSRGVF-FGMGLSNFLAA-IIGLAWFLK 459
                  L NF+  G + + +GL   LA+  I L+W LK
Sbjct: 409 -------LANFSPLGPYGYWIGLITGLASCAIALSWRLK 440


>pir||B83476 probable transporter PA1361 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9947303|gb|AAG04750.1|AE004565_9
           (AE004565) probable transporter [Pseudomonas aeruginosa]
           Length = 477
           
 Score = 87.4 bits (213), Expect = 3e-16
 Identities = 96/401 (23%), Positives = 153/401 (37%), Gaps = 9/401 (2%)

Query: 20  KTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTMAG 79
           K LL LA PI++  L        D    G+     L+A  +   I   +  L  G  +A 
Sbjct: 19  KELLTLAAPIMIAQLATTAMGFVDAVMAGRASPHDLAAVALGNSIWIPMFLLMTGTLLAT 78

Query: 80  FSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRPYAY 139
            + V Q  GAGD             L L    LS  +   +    L  M V P +   + 
Sbjct: 79  TAKVAQRHGAGDQPGTGPLVRQALWLALLIGPLSGAVLWWLSEPILGLMKVRPELIGPSL 138

Query: 140 RYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF----IFKL 195
            Y   I  G P + L+ V        G T+  + +    + LNI ++   I+    + K+
Sbjct: 139 LYLKGIALGFPAAALYHVLRCYTNGLGRTRPSMVLGIGGLLLNIPINYALIYGHFGMPKM 198

Query: 196 GVLGAALAT---VLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPSSI 252
           G  G   AT   +    +G +  V      +A    +  +  PD      +V VGLP  I
Sbjct: 199 GGPGCGWATGSVMWFMFLGMLFWVNKASIYRASQLFSRWEW-PDRATIGPLVAVGLPIGI 257

Query: 253 GQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEK 312
              A S  F V+  +I G  +   A + I       +  I   + MA+   V  N+GA  
Sbjct: 258 AVFAESSIFSVIALLIGGLDENVVAGHQIALNFSALVFMIPYSLGMAVTVRVGHNLGAGL 317

Query: 313 YERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISVPF 372
              A+  A   M      A  +  ++ + R  I  ++  DP VIA +  ++  F     F
Sbjct: 318 PRDARFAAGVGMAAALGYACVSASLMLLLREQIAAMYSPDPAVIAIAASLI-VFSALFQF 376

Query: 373 FNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFG 413
            + + V   G       T  +M+M++   WG  +P+ Y+ G
Sbjct: 377 SDALQVTAAGALRGYQDTRVTMIMTLFAYWGIGLPVGYSLG 417


>pir||H82186 probable multidrug resistance protein NorM VC1540 [imported] -
           Vibrio cholerae (group O1 strain N16961)
           >gi|9656046|gb|AAF94694.1| (AE004232) multidrug
           resistance protein NorM, putative [Vibrio cholerae]
           Length = 461
           
 Score = 85.8 bits (209), Expect = 9e-16
 Identities = 84/400 (21%), Positives = 161/400 (40%), Gaps = 12/400 (3%)

Query: 22  LLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTMAGFS 81
           L+KLA P+++ ++ Q      DT   G +    ++A  +A  I    +  G+G  MA   
Sbjct: 15  LIKLATPVLIASVAQTGMGFVDTIMAGGVSAIDMAAVSIAASIWLPSILFGVGLLMALVP 74

Query: 82  IVGQYIGAGDFKKA--NRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRPYAY 139
           +V Q  GAG   K       G + +L++    ++ L     +   + FM+V  ++     
Sbjct: 75  VVAQLNGAGRQHKIPFEVHQGLILALLVSVPIIAVLFQTQFI---IRFMDVEEAMATKTV 131

Query: 140 RYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF----IFKL 195
            Y   +   VP   LF    +       TK  + I  + + LNI L+ IF++      +L
Sbjct: 132 GYMHAVIFAVPAYLLFQALRSFTDGMSLTKPAMVIGFIGLLLNIPLNWIFVYGKFGAPEL 191

Query: 196 GVLGAALATVLSNAVGTIIGVKILMSGK--AGLKITLEDLKPDWKFYSKIVRVGLPSSIG 253
           G +G  +AT +   +  ++ +  +++ K  A +K+     KP  K   ++ R+G P +  
Sbjct: 192 GGVGCGVATAIVYWIMLLLLLFYIVTSKRLAHVKVFETFHKPQPKELIRLFRLGFPVAAA 251

Query: 254 QSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEKY 313
                  F V+  ++   G    AA+ +     + +      I  A+   V   +G +  
Sbjct: 252 LFFEVTLFAVVALLVAPLGSTVVAAHQVALNFSSLVFMFPMSIGAAVSIRVGHKLGEQDT 311

Query: 314 ERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISVPFF 373
           + A + A   ++   A A    L+  +FR  I  ++ ++  V+A +  +L  F       
Sbjct: 312 KGAAIAANVGLMTGLATACITALLTVLFREQIALLYTENQVVVALAMQLL-LFAAIYQCM 370

Query: 374 NGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFG 413
           + + VV  G              + +  W   +P  Y  G
Sbjct: 371 DAVQVVAAGSLRGYKDMTAIFHRTFISYWVLGLPTGYILG 410


>sp|P37340|YDHE_ECOLI HYPOTHETICAL 49.4 KDA PROTEIN IN RIBC-PYKF INTERGENIC REGION
           >gi|1742737|dbj|BAA15430.1| (D90809) ORF_ID:o319#7;
           similar to [SwissProt Accession Number P37340]
           [Escherichia coli] >gi|1742747|dbj|BAA15439.1| (D90810)
           ORF_ID:o319#7; similar to [SwissProt Accession Number
           P37340] [Escherichia coli]
           Length = 457
           
 Score = 79.2 bits (192), Expect = 9e-14
 Identities = 87/411 (21%), Positives = 162/411 (39%), Gaps = 17/411 (4%)

Query: 20  KTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTMAG 79
           + LL LA P+++  + Q      DT   G      ++A  +   I    +  G G  +A 
Sbjct: 9   RLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLAL 68

Query: 80  FSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRPYAY 139
             ++ Q  G+G  ++        F L  F S L  L+      +     N+ P++   A 
Sbjct: 69  TPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAV 128

Query: 140 RYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF----IFKL 195
            Y   +  G P    F V          TK  + +  + + +NI ++ IFI+    + +L
Sbjct: 129 GYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPEL 188

Query: 196 GVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLED--LKPDWKFYSKIVRVGLPSSIG 253
           G +G  +AT     V  +  V  +   ++   I  E    KPD     +++++GLP ++ 
Sbjct: 189 GGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALA 248

Query: 254 QSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEKY 313
                  F V+  ++   G V  A + I     + +  +   ++ A+   V   +G    
Sbjct: 249 LFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGST 308

Query: 314 ERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVI---AESKIVLEYFLISV 370
             A+  A   ++V   +A    +     R  I  ++ D+PEV+   A   ++   + IS 
Sbjct: 309 LDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQIS- 367

Query: 371 PFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFL 421
              + I V+ +G+      T     ++    W   +P     GYI A+T L
Sbjct: 368 ---DSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLP----SGYILALTDL 411


>pir||H75559 conserved hypothetical protein - Deinococcus radiodurans  (strain
           R1) >gi|6457769|gb|AAF09695.1|AE001873_5 (AE001873)
           conserved hypothetical protein [Deinococcus radiodurans]
           Length = 451
           
 Score = 79.2 bits (192), Expect = 9e-14
 Identities = 98/458 (21%), Positives = 180/458 (38%), Gaps = 50/458 (10%)

Query: 20  KTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTMAG 79
           + LL+LA P+VV+        +  T  +G+LG   L+A   A      +  + +G  ++ 
Sbjct: 16  RALLRLAGPVVVSQFAANALALIATAVIGRLGERELAAAAYANAAYYLVFIMVVGVMLSV 75

Query: 80  FSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPS--IRPY 137
              V Q  GAGD +   R+ G    L L    LSA++  L+  L+    N  P+   R  
Sbjct: 76  APRVAQAHGAGDARGVARALGGGLRLALL---LSAVMLPLMWALSFVLPNFAPAGVSRDL 132

Query: 138 AYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF----IF 193
              Y  V   G+  +  F+     +  TG       ++   V   +++ P   F    + 
Sbjct: 133 VAAYLRVYSLGMLPNLAFIALRGTLEGTGKPGAVTGVALTGVVWALLVAPALAFGWGPLP 192

Query: 194 KLGVLGAA-----LATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGL 248
           +LG+ GAA      A +++  +  +   ++  +G  G         P       + R+G 
Sbjct: 193 RLGLAGAAGASASAAWIMAALLWPLARRRVAYAGPLG---------PLGDEVRALFRLGW 243

Query: 249 PSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNV 308
           P  +   A    F V T ++  FG    AA+ +T + +     +  GI+ A G  V    
Sbjct: 244 PIGLTLGAEGGMFSVTTLLMARFGPEVLAAHNVTMQTITAFFMVPLGIASATGVRVGTEA 303

Query: 309 GAEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRV----PIFKVF--LDDPEVIAESKIV 362
           GA +  +A+    R  +V   ++   +L   V  +     +F VF  ++DP         
Sbjct: 304 GAGRLAQAR----RAGLVGLGLSSAVMLTFAVIELAAPRTVFSVFVNVNDPANAGLIAAA 359

Query: 363 LEYFLISVPF--FNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITF 420
             +  I+  F   +G+ V   G       T   +++S++  W               +  
Sbjct: 360 TGFLSIAALFQLMDGLQVTANGALRGLQDTRVPLLVSLVAYW---------------VVG 404

Query: 421 LGIRIPMAELFNFTSRGVFFGMGLSNFLAAIIGLAWFL 458
           LG+   ++ +    +RG++FG+     LA +  +  FL
Sbjct: 405 LGLGSVLSSVAGLGARGLWFGLTAGLTLAGLSLVGRFL 442


>pir||F70172 conserved hypothetical integral membrane protein BB0583 - Lyme
           disease spirochete >gi|2688514|gb|AAB91524.1| (AE001160)
           conserved hypothetical integral membrane protein
           [Borrelia burgdorferi]
           Length = 449
           
 Score = 77.3 bits (187), Expect = 4e-13
 Identities = 95/462 (20%), Positives = 187/462 (39%), Gaps = 42/462 (9%)

Query: 18  IEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTM 77
           I K L  +A P    +L+  +    D F +  LG   ++   +A  +      +  G   
Sbjct: 11  IIKELFVIAIPTAFESLLFQMVTFFDNFMISYLGSFHVTGVSLANRVTFLFFIIVFGLGT 70

Query: 78  AGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRPY 137
           A  + V Q I    F +  +S   +  +      +  + S L     +           +
Sbjct: 71  ALSAYVSQAIAKKKFLQVRQSFAYILLIGTTIGIIFFIFSFLFPRNIIKLFTANQDSLNF 130

Query: 138 AYRYAIVIFAGVPVSFLFMVFNAL----MRATGDTKTPVKISALTVFLNIILDPIFIFIF 193
              Y  +I     +S++ M ++ L     ++  + K P+ ++++ V +NI+ + I IF F
Sbjct: 131 GSEYLKII----SLSYVLMAYSFLSAMGFKSAKEVKIPLYVTSIVVLINIVFNYILIFGF 186

Query: 194 KLGVLGAALATVLSNAVGTII-GVKILMSGKAGLKITLEDLKPDWKFYSKIV-RVGLPSS 251
            +G+ GAA ATVL+  V  +   +  L+S  +  +I   D      F  K+V R  L   
Sbjct: 187 SMGIKGAAYATVLARIVEFVFYFLYSLISSNSYYRIKFGDF-----FAPKVVTRANLKLI 241

Query: 252 IGQSANSFGFVVLTRIIMGF----GDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQN 307
           I   ++   +V+   I+  F    G + YA++ + + L +    +  G+ +A G ++   
Sbjct: 242 IPVLSHEIFWVLSITILHAFYARVGSIEYASFAVASNLFDICFVLLHGMGLATGVVIGHL 301

Query: 308 VGAEKYERAKVIAERTMVVNFAIAGFAV-LVIGVFR-VPIFKVFLDDPEVIAESKIVLEY 365
           +  +K +  + +      + F +  F V L+IG+    P     LD PE+++    V  Y
Sbjct: 302 MIYDK-KHVRSVGFFLSFLGFLLGIFVVILLIGISSFAPYIFSKLDSPELVS----VFIY 356

Query: 366 FLISVPFFNGIFV-VVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLGIR 424
              S+  F      V+ GVF ++G       +    +  + +P++Y       + +  + 
Sbjct: 357 VFASIVIFKAFTAQVLVGVFRASGIPNVCFFIESGVIVFYTLPVAYLL-----VFYTNLS 411

Query: 425 IPMAELFNFTSRGVFFGMGLSNFLAAIIGLAWFLKGSWMRRI 466
           +P+          V F + L   +  I  +  F    W+R I
Sbjct: 412 LPI----------VVFIVNLEEIIKNIFIIIEFFHDDWIREI 443


>pir||A64924 probable membrane protein ydhE precursor - Escherichia coli
           >gi|1549276|gb|AAB47941.1| (U68703) hypothetical protein
           YdhE [Escherichia coli] >gi|1787953|gb|AAC74735.1|
           (AE000261) putative transport protein [Escherichia coli
           K12]
           Length = 457
           
 Score = 76.9 bits (186), Expect = 5e-13
 Identities = 86/411 (20%), Positives = 161/411 (38%), Gaps = 17/411 (4%)

Query: 20  KTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTMAG 79
           + LL LA P+++  + Q       T   G      ++A  +   I    +  G G  +A 
Sbjct: 9   RLLLALAIPVILAQIAQTAMGFVSTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLAL 68

Query: 80  FSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRPYAY 139
             ++ Q  G+G  ++        F L  F S L  L+      +     N+ P++   A 
Sbjct: 69  TPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAV 128

Query: 140 RYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF----IFKL 195
            Y   +  G P    F V          TK  + +  + + +NI ++ IFI+    + +L
Sbjct: 129 GYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPEL 188

Query: 196 GVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLED--LKPDWKFYSKIVRVGLPSSIG 253
           G +G  +AT     V  +  V  +   ++   I  E    KPD     +++++GLP ++ 
Sbjct: 189 GGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALA 248

Query: 254 QSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEKY 313
                  F V+  ++   G V  A + I     + +  +   ++ A+   V   +G    
Sbjct: 249 LFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGST 308

Query: 314 ERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVI---AESKIVLEYFLISV 370
             A+  A   ++V   +A    +     R  I  ++ D+PEV+   A   ++   + IS 
Sbjct: 309 LDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQIS- 367

Query: 371 PFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFL 421
              + I V+ +G+      T     ++    W   +P     GYI A+T L
Sbjct: 368 ---DSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLP----SGYILALTDL 411


>gb|AAD30646.1|AC006085_19 (AC006085) Hypothetical protein [Arabidopsis thaliana]
           Length = 501
           
 Score = 76.9 bits (186), Expect = 5e-13
 Identities = 76/301 (25%), Positives = 132/301 (43%), Gaps = 22/301 (7%)

Query: 102 LFSLVLFFSTLSALISILILPLALDFMNV---TPSIRPYAYRYAIVIFAGVPVSFLFMVF 158
           LF  V   S    L+S         FM V   +P +RP + RY  +   G P   L +  
Sbjct: 178 LFQAVFLISAAKPLLS---------FMGVKHDSPMMRP-SQRYLSLRSLGAPAVLLSLAA 227

Query: 159 NALMRATGDTKTPVKISALTVFLNIILDPIFIFIFKLGVLGAALATVLSNAVGTIIGVKI 218
             + R   DT TP+  + +    NIILDPIFIF+F+LGV GAA A V+S  +   I +  
Sbjct: 228 QGVFRGFKDTTTPLFATVIGDVTNIILDPIFIFVFRLGVTGAATAHVISQYLMCGILLWK 287

Query: 219 LMSGKAGLKITLEDLKPDWKFYSKIVRVGLPSSIGQSANSFGFVVLTRIIMGFGDVTYAA 278
           LM      ++ + ++      + + ++ G    +   A +F   +   +    G  + AA
Sbjct: 288 LMG-----QVDIFNMSTKHLQFCRFMKNGFLLLMRVIAVTFCVTLSASLAAREGSTSMAA 342

Query: 279 YVITTRLVNFITSISRGISMAMGTMVAQNVGAEKYERAKVIAERTMVVNFAIAGFAVLVI 338
           + +  ++    + ++ G ++A   ++A     + Y+RA   A R + +   +     +++
Sbjct: 343 FQVCLQVWLATSLLADGYAVAGQAILASAFAKKDYKRAAATASRVLQLGLVLGFVLAVIL 402

Query: 339 GVFRVPIFKVFLDDPEVIAESKIVLEYFLISVPFFNGIFVVVTGV---FSSAGHTVKSMV 395
           G       +VF  D +V+    I L +   + P  N +  V  GV    S  G+   S+V
Sbjct: 403 GAGLHFGARVFTKDDKVLHLISIGLPFVAGTQP-INALAFVFDGVNFGASDFGYAAASLV 461

Query: 396 M 396
           M
Sbjct: 462 M 462


>gi|8922709 hypothetical protein FLJ10847 [Homo sapiens]
           >gi|7023138|dbj|BAA91852.1| (AK001709) unnamed protein
           product [Homo sapiens]
           Length = 570
           
 Score = 75.7 bits (183), Expect = 1e-12
 Identities = 93/432 (21%), Positives = 182/432 (41%), Gaps = 33/432 (7%)

Query: 5   KVKAMRREILEGPIEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPI 64
           ++ A R E+      + LL LA P  +  L+  L +   + + G LG+  L A  +A  +
Sbjct: 27  RLSAFREEL------RALLVLAGPAFLVQLMVFLISFISSVFCGHLGKLELDAVTLAIAV 80

Query: 65  IG-TLMALGMGFTMAGFSIVGQYIGAGDFKKAN----RSAGALFSLVLFFSTLSALISIL 119
           I  T +++G G + A  +++ Q  G+ + K       RSA     LVL           L
Sbjct: 81  INVTGVSVGFGLSSACDTLISQTYGSQNLKHVGVILQRSA-----LVLLLCCFPCWALFL 135

Query: 120 ILPLALDFMNVTPSIRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTV 179
                L      P +      Y  +    +P +FL+M+    +   G     +       
Sbjct: 136 NTQHILLLFRQDPDVSRLTQTYVTIFIPALPATFLYMLQVKYLLNQGIVLPQIVTGVAAN 195

Query: 180 FLNIILDPIFIFIFKLGVLGAALATVLSNAVGT------IIGVKILMSGKAGLKITLEDL 233
            +N + + +F+    LGV+G+ALA ++S           I+G K+  +   G   +LE L
Sbjct: 196 LVNALANYLFLHQLHLGVIGSALANLISQYTLALLLFLYILGKKLHQATWGGW--SLECL 253

Query: 234 KPDWKFYSKIVRVGLPSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSIS 293
           + DW   +  +R+ +PS +      + + V + +    G V   A  I   L   +  + 
Sbjct: 254 Q-DW---ASFLRLAIPSMLMLCMEWWAYEVGSFLSGILGMVELGAQSIVYELAIIVYMVL 309

Query: 294 RGISMAMGTMVAQNVGAEKYERAKVIAERTMVVN--FAIAGFAVLVIGVFRVPIFKVFLD 351
            G S+A    V   +GA   E+A+  +  ++++   FA+A F+VL++   +  +  +F  
Sbjct: 310 AGFSVAASVRVGNALGAGDMEQARKSSTVSLLITVLFAVA-FSVLLLSC-KDHVGYIFTT 367

Query: 352 DPEVIAESKIVLEYFLISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYA 411
           D ++I     V+  + +S   F  +     GV   +G+     +++ +  +   +P+  A
Sbjct: 368 DRDIINLVAQVVPIYAVS-HLFEALACTSGGVLRGSGNQKVGAIVNTIGYYVVGLPIGIA 426

Query: 412 FGYIPAITFLGI 423
             +   +  +G+
Sbjct: 427 LMFATTLGVMGL 438


>pir||E82527 multidrug efflux protein XF2686 [imported] - Xylella fastidiosa
           (strain 9a5c) >gi|9107925|gb|AAF85483.1|AE004074_7
           (AE004074) multidrug efflux protein [Xylella fastidiosa]
           Length = 469
           
 Score = 74.5 bits (180), Expect = 2e-12
 Identities = 103/457 (22%), Positives = 177/457 (38%), Gaps = 49/457 (10%)

Query: 18  IEKTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTM 77
           +  TLL LA P+V+ ++   L         G      L+A  +   ++   M + MG  +
Sbjct: 30  VRPTLL-LALPLVLGHVSTGLIGFVLNVIAGHHSTVTLAASTIGTALLWLPMLVPMGTLI 88

Query: 78  AGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALIS---ILILPLALDFMNVTPSI 134
           +   +V Q  GA    +  R  G LF   L+ + L  L+    + ++P  L    + P I
Sbjct: 89  SLTVLVSQLHGA----ERERDIGPLFRQALWLAMLLGLVMFTFLSVVPALLPLFGIVPDI 144

Query: 135 RPYAYRYAIVIFAG---VPVSFLFMVFNALMRATGDTKTPVKISALTVF--LNIILDPIF 189
            P A ++  V+  G    P+ F    F   M  T  T   +    L V   L+  L    
Sbjct: 145 VPGAAKFLHVVRWGSLAFPLYFCMRYFCEGMHCTFPTML-LGFGGLLVLVPLSYALTYGR 203

Query: 190 IFIFKLGVLGAALATVLSNAVGTIIGVKILMSGK--AGLKITLEDLKPDWKFYSKIVRVG 247
               + GV G  +ATV+   +  ++    L   +  A L++      P W     ++ +G
Sbjct: 204 FGFSEYGVEGLGIATVMVMWLQAVVFALYLWRSRRFAHLQLFAHLELPCWARIRDLLNIG 263

Query: 248 LPSSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQN 307
           LP  I        F+V T +I  FG    AA+ I   +      I  G++ A    +   
Sbjct: 264 LPIGISILMEGGLFIVTTLLIGRFGTDEIAAHQIALSVAQLCFMIPMGVAEATTVRIGHA 323

Query: 308 VGAEKYERAKVIAERTMVVNFAIAGFAVLV--------IGVFRVPIFKVFLDDPEVIAES 359
           VG     R  ++  R +    A AG+A+++        + +    +      D  V+A  
Sbjct: 324 VG-----RCDLLVMRRV----AWAGYAIVIGTQTLSASVLLLGYDVIVAAYTDDLVVASL 374

Query: 360 KIVLEYFLISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAIT 419
              L  F     F +G+ ++ +GV      T   M+++M+  WG  +PL    G+     
Sbjct: 375 ASKLLLFAAIFQFPDGLQMLSSGVLRGMKDTRVPMLLAMISYWGLGMPLGLGLGF----- 429

Query: 420 FLGIRIPMAELFNFTSRGVFFGMGLSNFLAAIIGLAW 456
                        + SRG++ G+ +    AA + L W
Sbjct: 430 ----------ALEWNSRGMWIGL-IIGLTAAAVLLGW 455


>pir||T50435 conserved hypothetical protein SPCC4B3.13 [imported] - fission
           yeast (Schizosaccharomyces pombe)
           >gi|6434021|emb|CAB60687.1| (AL132870) conserved
           hypothetical protein [Schizosaccharomyces pombe]
           Length = 539
           
 Score = 73.0 bits (176), Expect = 7e-12
 Identities = 77/343 (22%), Positives = 154/343 (44%), Gaps = 13/343 (3%)

Query: 22  LLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVA-WPIIGTLMALGMGFTMAGF 80
           L+K A P+V+ +L+Q    +T  F LG LG+  L+A  ++      T  A+  G   A  
Sbjct: 100 LIKFATPVVLTSLLQYGEVVTTVFSLGHLGKTELAAASLSNMTATITAFAIYQGIVSALD 159

Query: 81  SIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRPYAYR 140
           ++  Q  G+G+++        + +++L       LI   I  + L F+   P    +A +
Sbjct: 160 TVGTQSFGSGNYEMVGLHLQRILAILLLIQFPIFLIWWKIEGILL-FLRQDPLTCMFAAK 218

Query: 141 YAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIFI--FKLGVL 198
           Y  V+    P   LF      ++  G       I A+ V +NI L+ +F++      G L
Sbjct: 219 YMRVMMLASPAYALFEALKRFLQVQGIFHPVTYILAIVVPINIFLNYLFVWSPWVGFGFL 278

Query: 199 GA--ALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPSSIGQSA 256
           GA  A+A  L +A   +I   + ++G+        +   +W     + R+ +P  I   +
Sbjct: 279 GAPVAVALTLWSACAVLIIYIMKVNGRQAWGGFSREALKNW---GPLCRLAVPGVIMICS 335

Query: 257 NSFGFVVLTRI--IMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEKYE 314
             + F ++T    ++G  ++   + + TT  +++  +++ G++ A  T V   +GA   +
Sbjct: 336 EYWAFELVTFASGVLGTTELASMSVLSTTSTLSY--NLAFGVAAAAATRVGNLIGAGNTK 393

Query: 315 RAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIA 357
            AK+    ++ +  AI     +++ + R     +F  D +V+A
Sbjct: 394 LAKLATHVSINLGAAIGVIIAVILFLTRNTWTYIFTSDKDVVA 436


>pir||G70693 probable dinF protein - Mycobacterium tuberculosis (strain H37RV)
           >gi|1648884|emb|CAB03650.1| (Z81331) dinF [Mycobacterium
           tuberculosis]
           Length = 439
           
 Score = 72.6 bits (175), Expect = 9e-12
 Identities = 94/430 (21%), Positives = 179/430 (40%), Gaps = 35/430 (8%)

Query: 20  KTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTMAG 79
           + + +LA P +     + LY + D   +G+LG  A+S  G+A   IG+L+ LG+  + A 
Sbjct: 11  RQIAQLALPALGVLAAEPLYLLFDIAVVGRLG--AISLAGLA---IGSLV-LGLVGSQAT 64

Query: 80  FSIVGQYIGAGD-FKKANRSAGALFSLVLFFSTLS--ALISILILPLALDFMNVTPS--- 133
           F   G    A   +   NR A     +   +  L   AL+ +++   A   ++   S   
Sbjct: 65  FLSYGTTARAARRYGAGNRVAAVTEGVQATWLALGLGALVVVVVEATATPLVSAIASGDG 124

Query: 134 IRPYAYRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF-- 191
           I   A  +  +   G P   + +  N  +R   DT  P++        + +L P+ ++  
Sbjct: 125 ITAAALPWLRIAILGTPAILVSLAGNGWLRGVQDTVRPLRYVVAGFGSSALLCPLLVYGW 184

Query: 192 --IFKLGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLP 249
             + + G+ G+A+A ++   +  ++    L++ +  L+       PD       + +   
Sbjct: 185 LGLPRWGLTGSAVANLVGQWLAALLFAGALLAERVSLR-------PDRAVLGAQLMMARD 237

Query: 250 SSIGQSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVG 309
             +   A    +V    +   FG    AA+ +  +L   +  +   +++A  ++V   +G
Sbjct: 238 LIVRTLAFQVCYVSAAAVAARFGAAALAAHQVVLQLWGLLALVLDSLAIAAQSLVGAALG 297

Query: 310 AEKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLIS 369
           A     AK +A R    +   AG     +G+    +  +F DD  V+A   +   + ++ 
Sbjct: 298 AGDAGHAKAVAWRVTAFSLLAAGILAAALGLGSSVLPGLFTDDRSVLAAIGVPWWFMVVQ 357

Query: 370 VPFFNGIFVVVTGVFSSAGH-------TVKSMVMSMLRL-WGFRIPLSYAFGYIPAITFL 421
           +P F GI   V GV   AG        TV S ++  L L W   + L+Y +G     + L
Sbjct: 358 LP-FAGIVFAVDGVLLGAGDAAFMRTATVASALVGFLPLVW---LSLAYGWGLAGIWSGL 413

Query: 422 GIRIPMAELF 431
           G  I +  +F
Sbjct: 414 GTFIVLRLIF 423


>pir||A82984 hypothetical protein PA5294 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9951609|gb|AAG08679.1|AE004942_2
           (AE004942) hypothetical protein [Pseudomonas aeruginosa]
           Length = 488
           
 Score = 70.6 bits (170), Expect = 4e-11
 Identities = 77/304 (25%), Positives = 125/304 (40%), Gaps = 7/304 (2%)

Query: 20  KTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTMAG 79
           K +L+LA P++   L  V    TDT  +GKLG +AL+A G+       +    +G   A 
Sbjct: 10  KAILRLAGPLIAAQLAYVAMVFTDTVMMGKLGPDALAAGGLGAVSYAFVSTFCVGVVAAV 69

Query: 80  FSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRPYAY 139
            ++V    G  D   A  +A +   +    +  + L+   + PL L F    P     A 
Sbjct: 70  GNLVAIRHGCDDAAGAAAAARSGLWVGAALALAAGLLLWNLRPLLLVF-GQAPQTVDGAM 128

Query: 140 RYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFI----FIFKL 195
           ++   +   +P    FMV      A       + IS L    N+ L+  FI     + +L
Sbjct: 129 QFLHSLTFALPGYMAFMVLRGFTSAIDRAGPVMAISVLGALANLALNYSFIEGLFGLPRL 188

Query: 196 GVLGAALATVL-SNAVGTIIGVKILMSGKAGLKITLEDL-KPDWKFYSKIVRVGLPSSIG 253
           G+ G  L T L  N +  ++ + I +         L  L +P      +I+R+GLP    
Sbjct: 189 GLAGIGLVTALVMNCMPLLLALYIRLQPAYAEYSLLRGLGRPQRAMVEEILRLGLPIGGT 248

Query: 254 QSANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGAEKY 313
            +  S  F V T  +   GD   AA+ I  + V     +  G+S A    + Q+ GA + 
Sbjct: 249 YAVESGMFTVATLCMGIIGDHALAAHQIAIQAVYVAFMVPVGLSYATTYRIGQHFGAGRL 308

Query: 314 ERAK 317
             A+
Sbjct: 309 LEAR 312


>gb|AAC67367.1| (AC005499) hypothetical protein [Arabidopsis thaliana]
           Length = 486
           
 Score = 70.2 bits (169), Expect = 5e-11
 Identities = 96/458 (20%), Positives = 196/458 (41%), Gaps = 37/458 (8%)

Query: 21  TLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGM--GFTMA 78
           +L K+A PIV+ +L+    +I   ++L  LG+  L+   +A    G +  + +  G ++ 
Sbjct: 9   SLTKIACPIVMTSLLIFSRSIISMWFLSHLGKVELAGGALAMGF-GNITGVSVLKGLSVG 67

Query: 79  GFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRPYA 138
              I GQ  GA  +   + +   +F L++  S   A+  + I P+ L  +   P I   A
Sbjct: 68  MDPICGQAFGAKRWTVLSHTFQKMFCLLIVVSVPIAVTWLNIEPIFLR-LGQDPDITKVA 126

Query: 139 YRYAIVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIFIF----K 194
             Y +     +    +       +R  G T +P+ ISA+   ++I+L P+F ++F    +
Sbjct: 127 KTYMLFFVPELLAQAMLHPLRTFLRTQGLT-SPLTISAI---VSILLHPLFNYVFVVRMR 182

Query: 195 LGVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDL--KPDWKFYSKIVRVGLPSSI 252
           LGV G A+A    N +   +G+ +       L    E L  +  ++ +  ++ +  PS+I
Sbjct: 183 LGVKGVAIAMAF-NTMNIDVGLLVYTCFSDSLIKPWEGLALRSLFRGWWPLLSLAAPSAI 241

Query: 253 GQSANSFGFVVLTRI--IMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGA 310
                 + + ++  +  ++G    + AA  I  +    +  +   IS A+ T V   +G 
Sbjct: 242 SVCLEYWWYEIMLFLCGLLGNPKASVAAMGILIQTTGILYVVPFAISSAIATRVGHALGG 301

Query: 311 EKYERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISV 370
            +  RA+      +++  A    A + +   R    K+F D+PE++          LIS 
Sbjct: 302 GQPTRAQCTTVIGLILAVAYGLAAAVFVTALRSVWGKMFTDEPEILG---------LISA 352

Query: 371 PFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLGIRIPMAEL 430
                  + + G+    G++ ++    +L   G   P   A   + A   +G+ + +   
Sbjct: 353 A------LPILGL-CEIGNSPQTAACGVLT--GTARPKDGARVNLCAFYIVGLPVAVTTT 403

Query: 431 FNFT--SRGVFFGMGLSNFLAAIIGLAWFLKGSWMRRI 466
           F F    RG++FG+  +     ++ L   ++  W  ++
Sbjct: 404 FGFKVGFRGLWFGLLSAQMTCLVMMLYTLIRTDWSHQV 441


>gb|AAG27731.1|AF312031_1 (AF312031) multi-drug efflux transporter [Burkholderia
           vietnamiensis]
           Length = 462
           
 Score = 69.5 bits (167), Expect = 8e-11
 Identities = 86/400 (21%), Positives = 163/400 (40%), Gaps = 19/400 (4%)

Query: 24  KLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFTMAGFSIV 83
           +LA P+ +  L Q+  ++TDT  LG LG ++L+A G+       ++ +  G   +    V
Sbjct: 25  RLAAPLAIAQLSQMAMSVTDTVLLGSLGPDSLAAGGLGANFFFVIVTVLQGVLSSVSVSV 84

Query: 84  GQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLA---LDFMNVTPSIRPYAYR 140
               GA    +A      ++      S L A+ +++ L L+   L   +  P++  +   
Sbjct: 85  AHARGA----QAEHRVPHIYWTGFVLSVLLAIPAVVALSLSEPLLLMFHEPPTLAQHVGE 140

Query: 141 YA-IVIFAGVPVSFLFMVFNALMRATGDTKTPVKISALTVFLNIILDPIFIF----IFKL 195
           Y  I+ FA +       +  A + A G  +  + +S   + +N +L+   I     + +L
Sbjct: 141 YTGILRFAALGSLIGVGLMRAFLPAIGAARRLLWVSIGGIGVNAVLNYGLIHGAYGLPRL 200

Query: 196 GVLGAALATVLSNAVGTIIGVKILMSGKAGLKITLEDLKPDWKFYSKIVRVGLPSSIGQS 255
           G LG+A+AT ++  + T   +  L+ G+A  +  +   +P      +++ +G P +I   
Sbjct: 201 GFLGSAVATTITIWL-TAFALIWLLHGRARFRHFVSAARPKLPMMGELIGIGWPVAITYG 259

Query: 256 ANSFGFVVLTRIIMGFGDVTYAAYVITTRLVNFITSISRGISMAMGTMVAQNVGA---EK 312
             S  F+     +   G    AA+ I   + +    +   I  A    V   +GA     
Sbjct: 260 VESTLFLATGLTVGVLGATALAAHQIALNVASVAFMVPLAIGQAANVRVGYWIGAGDPVA 319

Query: 313 YERAKVIAERTMVVNFAIAGFAVLVIGVFRVPIFKVFLDDPEVIAESKIVLEYFLISVPF 372
              A  +A    V   +++G  VL++    +    + LDDP   A   +      I+  F
Sbjct: 320 ARHAGFVALGLGVAFMSLSGL-VLILAPHAIVGLYLHLDDPANAATVSLAASLLGIAAVF 378

Query: 373 --FNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSY 410
              +G+  V +G       T   M+ +    WG   P  Y
Sbjct: 379 QIVDGMQTVGSGALRGLRDTRIPMLAATFGYWGIGFPTGY 418


>dbj|BAA97535.1| (AB028606) emb|CAA66809.1~gene_id:F16F17.3~strong similarity to
           unknown protein [Arabidopsis thaliana]
           Length = 498
           
 Score = 69.5 bits (167), Expect = 8e-11
 Identities = 99/454 (21%), Positives = 189/454 (40%), Gaps = 46/454 (10%)

Query: 20  KTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTL---MALGMGFT 76
           K L  LA P +  ++ Q         + G +   AL+A  V   +I      + LGMG  
Sbjct: 47  KKLWYLAGPAIFMSITQYSLGAATQVFAGHISTIALAAVSVENSVIAGFSFGVMLGMGSA 106

Query: 77  MAGFSIVGQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDFMNVTPSIRP 136
           +   ++ GQ  GAG            + ++   + + +L+ I   P+ L F+  TP+I  
Sbjct: 107 LE--TLCGQAFGAGKLSMLGVYLQRSWVILNVTAVILSLLYIFAAPI-LAFIGQTPAISS 163

Query: 137 YAYRYAIVIFAGVPVSFLFMV---FNALMRATGDTKTPVKISALTVFLNIILDPIFIFIF 193
               ++I +   +P  F + V       +++         ISA+ + L+++L    I   
Sbjct: 164 ATGIFSIYM---IPQIFAYAVNYPTAKFLQSQSKIMVMAAISAVALVLHVLLTWFVIEGL 220

Query: 194 KLGVLGAALATVLSNAVGTIIGVKILM-----SGKAGLKITLEDLKPDWKFYSKIVRVGL 248
           + G  G  LA VL+ +   I+  +++       G+A    + E     W F    VR+ L
Sbjct: 221 QWGTAG--LAVVLNASWWFIVVAQLVYIFSGTCGEAWSGFSWEAFHNLWSF----VRLSL 274

Query: 249 PSSIGQSANSFGFVVLTRIIMGF---GDVTYAAYVITTRLVNFITSISRGISMAMGTMVA 305
            S++      + +++   +  G+    +++ AA  I   ++ +   I+ G++ A+   V+
Sbjct: 275 ASAVMLCLEVW-YLMAVILFAGYLKNAEISVAALSICMNILGWTAMIAIGMNAAVSVRVS 333

Query: 306 QNVGAEKYERAKVIAERTMVVNFAIAGFAV-LVIGVFRVPIFKVFLDDPEVIAESKIVLE 364
             +GA K+ R    +    V+   + G A+ + + +FR     +F+ D EVI   K +  
Sbjct: 334 NELGA-KHPRTAKFSLLVAVITSTVIGLAISIALLIFRDKYPSLFVGDEEVIIVVKDLTP 392

Query: 365 YFLISVPFFNGIFVVVTGVFSSAGHTVKSMVMSMLRLWGFRIPLSYAFGYIPAITFLGIR 424
              +S+   N +  V++GV   AG       ++++  + F IP     GY          
Sbjct: 393 ILAVSI-VINNVQPVLSGVAVGAGWQAVVAYVNIVCYYVFGIPFGLLLGY---------- 441

Query: 425 IPMAELFNFTSRGVFFGMGLSNFLAAIIGLAWFL 458
                  NF   G++ GM L+  +   I L W +
Sbjct: 442 -----KLNFGVMGIWCGM-LTGTVVQTIVLTWMI 469


>dbj|BAB10095.1| (AB023028) gb|AAF34304.1~gene_id:K20J1.11~strong similarity to
           unknown protein [Arabidopsis thaliana]
           Length = 502
           
 Score = 69.5 bits (167), Expect = 8e-11
 Identities = 88/390 (22%), Positives = 167/390 (42%), Gaps = 67/390 (17%)

Query: 20  KTLLKLAWPIVVNNLIQVLYNITDTFWLGKLGREALSAPGVAWPIIGTLMALGMGFT-MA 78
           K +  +++P+   +++  L N+T    +G+LG   L+             AL +GFT + 
Sbjct: 28  KRIWDISFPVAAMSILNYLKNMTSVVCMGRLGSLELAGG-----------ALAIGFTNIT 76

Query: 79  GFSIV-----------GQYIGAGDFKKANRSAGALFSLVLFFSTLSALISILILPLALDF 127
           G+S++           GQ IG+ +   A+ +      L+L  S          LP++L +
Sbjct: 77  GYSVLSGLATGMEPLCGQAIGSKNPSLASLTLKRTIFLLLLAS----------LPISLLW 126

Query: 128 MNVTPSIRPYAYRYAIVIFAGVPVSFLF--MVFNALM-------RATGDTKTPVKISALT 178
           +N+ P +     ++ I   A +  SF    ++ N+ +       R  G T   +  + ++
Sbjct: 127 LNLAPLMLMLRQQHDITRVASLYCSFSLPDLLANSFLHPLRIYLRCKGTTWPLMWCTLVS 186

Query: 179 VFLNIILDPIFIFIFKLGVLGAALATVLSNAVG-TIIGVKILMSGKAGLKITLEDLKPDW 237
           V L++ +   F F   LGV G A+++ L+N +  +++   I +      K T + L  D 
Sbjct: 187 VLLHLPITAFFTFYISLGVPGVAVSSFLTNFISLSLLLCYIYLENNNNDKTTSKSLCLDT 246

Query: 238 KF-------------YSKIVRVGLPSSIGQSANSFGFVVLTRIIMGF---GDVTYAAYVI 281
                          +S +V+  +PS I      + +  +T ++ G+     V  AA  I
Sbjct: 247 PLMLYGSRDSGENDVWSTLVKFAVPSCIAVCLEWWWYEFMT-VLAGYLPEPKVALAAAAI 305

Query: 282 TTRLVNFITSISRGISMAMGTMVAQNVGAEKYERAKVIAERTMVVNFAIAGFAVLVIGVF 341
             +  + + +I   +S A+ T V+  +GA + E+AK  A   +    A++ F ++   V 
Sbjct: 306 VIQTTSLMYTIPTALSAAVSTRVSNELGAGRPEKAKTAATVAVGAAVAVSVFGLVGTTVG 365

Query: 342 RVPIFKVFLDDPEVIAESKIVLEYFLISVP 371
           R    KVF  D       K+VLE     +P
Sbjct: 366 REAWGKVFTAD-------KVVLELTAAVIP 388


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.330    0.144    0.423 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 154097004
Number of Sequences: 2977
Number of extensions: 6268290
Number of successful extensions: 19731
Number of sequences better than 1.0e-10: 65
Number of HSP's better than  0.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 47
Number of HSP's that attempted gapping in prelim test: 19519
Number of HSP's gapped (non-prelim): 85
length of query: 468
length of database: 189,106,746
effective HSP length: 54
effective length of query: 414
effective length of database: 156,788,448
effective search space: 64910417472
effective search space used: 64910417472
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.8 bits)
S2: 167 (69.5 bits)