BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1451 (hpcE) DE:2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE
ISOMERASE.
         (225 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

sp|Q9UYW0|YE51_PYRAB HYPOTHETICAL PROTEIN PAB1451 >gi|7448788|pi...   454  e-127
sp|O58377|Y643_PYRHO HYPOTHETICAL PROTEIN PH0643 >gi|7448782|pir...   425  e-118
sp|Q59050|YG56_METJA HYPOTHETICAL PROTEIN MJ1656 >gi|2127713|pir...   236  1e-61
pir||A69068 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Meth...   218  5e-56
emb|CAB46032.1| (Z97340) isomerase like protein [Arabidopsis tha...   211  7e-54
gi|11499807 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-...   208  3e-53
pir||D70854 hypothetical protein Rv2993c - Mycobacterium tubercu...   206  2e-52
gb|AAK42882.1| 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hp...   203  2e-51
dbj|BAA95083.1| (AB041600) unnamed protein product [Mus musculus]     201  6e-51
dbj|BAB00076.1| (AB022217) isomerase-like protein [Arabidopsis t...   200  1e-50
pir||T29076 hypothetical protein SC1C2.27 - Streptomyces coelico...   199  3e-50
pir||S77124 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxylas...   192  4e-48
pir||T45421 probable 2-hydroxyhepta-2,4-diene-1,7- dioate isomae...   192  4e-48
pir||E75376 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/ 5-car...   189  2e-47
gi|11431155 CGI-105 protein [Homo sapiens]                            187  8e-47
dbj|BAB05724.1| (AP001514) 2-hydroxyhepta-2,4-diene-1,7-dioate i...   187  1e-46
gi|7705608 CGI-105 protein [Homo sapiens] >gi|4929679|gb|AAD3410...   186  2e-46
pir||C75575 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/ 5-car...   185  3e-46
pir||C71425 hypothetical protein - Arabidopsis thaliana               183  1e-45
pir||T03559 2-hydroxyhepta-2,4-diene-1, 7-dioateisomerase/ 5-car...   182  3e-45
dbj|BAB05719.1| (AP001514) 2-hydroxyhepta-2,4-diene-1,7-dioate i...   175  3e-43
pir||C69837 5-oxo-1,2,5-tricarboxilic-3-penten acid de homolog y...   173  1e-42
gb|AAG19447.1| (AE005037) 2-hydroxyhepta-2,4-diene-1,7-dioate is...   173  1e-42
emb|CAB65580.1| (AL136058) putative 2-hydroxyhepta-2,4-diene-1,7...   170  1e-41
sp|P34673|YO23_CAEEL HYPOTHETICAL 23.3 KDA PROTEIN ZK688.3 IN CH...   168  4e-41
gb|AAF55854.1| (AE003733) CG5793 gene product [Drosophila melano...   167  9e-41
emb|CAB55708.1| (AL117387) putative 2-hydroxyhepta-2,4-diene-1,7...   166  2e-40
sp|P76004|YCGM_ECOLI PROTEIN YCGM >gi|7448786|pir||A64864 probab...   165  4e-40
sp|Q46978|HPAG_ECOLI 4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTI...   164  1e-39
sp|Q9RPU5|HPAG_SALDU 4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTI...   161  9e-39
emb|CAC12279.1| (AL445066) 2-hydroxyhepta-2, 4-diene-1, 7-dioate...   159  2e-38
gb|AAF55945.1| (AE003737) CG6028 gene product [Drosophila melano...   159  2e-38
pir||G83604 conserved hypothetical protein PA0318 [imported] - P...   159  4e-38
pir||G83131 conserved hypothetical protein PA4122 [imported] - P...   156  2e-37
gi|6324161 Ynl168cp [Saccharomyces cerevisiae] >gi|1730800|sp|P5...   156  2e-37
pir||T50353 homolog to prokaryotic 2-hydroxyhepta-2,4-diene-1,7-...   152  4e-36
pir||A83338 conserved hypothetical protein PA2471 [imported] - P...   152  5e-36
emb|CAC11884.1| (AL445065) probable 2-hydroxyhepta-2, 4-diene-1,...   152  5e-36
sp|P37352|HPCE_ECOLI HOMOPROTOCATECHUATE CATABOLISM BIFUNCTIONAL...   146  2e-34
pir||H72757 hypothetical protein APE0053 - Aeropyrum pernix (str...   145  6e-34
dbj|BAA25605.1| (D88014) homologous to HpcE (HHDD isomerase) pro...   144  8e-34
emb|CAA12268.1| (AJ224977) ORF 2 [Sphingomonas sp. RW5]               144  8e-34
gi|11497711 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-...   141  7e-33
gb|AAG39451.1| (AF173167) probable maleylpyruvate isomerase [Pse...   136  2e-31
pir||B81094 isomerase, probable NMB1338 [imported] - Neisseria m...   131  8e-30
gb|AAF49840.1| (AE003539) CG11251 gene product [Drosophila melan...   129  3e-29
pir||T50940 DitD protein [imported] - Pseudomonas abietaniphila ...   129  4e-29
pir||C81847 probable hydrolase NMA1552 [imported] - Neisseria me...   129  4e-29
gb|AAC69614.1| (AF061446) unknown [Chromobacterium violaceum]         123  2e-27
dbj|BAA36035.1| (D90753) ZK688.3 protein [Escherichia coli]           122  3e-27
emb|CAA73581.1| (Y13118) ORF1 [Sphingomonas sp.]                      122  5e-27
emb|CAA73583.1| (Y13118) ORF2 [Sphingomonas sp.]                      120  1e-26
pir||F83131 conserved hypothetical protein PA4121 [imported] - P...   117  1e-25
dbj|BAB04790.1| (AP001510) unknown conserved protein in others [...   115  6e-25
gb|AAD12620.1| (AF036940) fumarylpyruvate hydrolase [Ralstonia s...   114  1e-24
pir||A82389 conserved hypothetical protein VCA1004 [imported] - ...   101  1e-20
pir||H81417 hypothetical protein Cj0021c [imported] - Campylobac...   100  1e-20
pir||T50935 isomerase/decarboxylase homolog DitH [imported] - Ps...   100  2e-20
gb|AAK42651.1| 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hp...    99  5e-20
pir||C70585 hypothetical protein Rv0939 - Mycobacterium tubercul...    86  4e-16
gb|AAB58814.1| (U38978) homolog to 2-hydroxyhepta-2,4-diene-1,7-...    82  8e-15
dbj|BAA87171.1| (AB027867) Hypothetical protein [Schizosaccharom...    80  2e-14
gb|AAK43045.1| 2-hydroxyhepta-2 ,4-diene-1,7-dioate isomerase (h...    80  3e-14

>sp|Q9UYW0|YE51_PYRAB HYPOTHETICAL PROTEIN PAB1451 >gi|7448788|pir||A75051
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase. PAB1451 -
           Pyrococcus abyssi (strain Orsay)
           >gi|5458815|emb|CAB50302.1| (AJ248287)
           2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE.
           [Pyrococcus abyssi]
           Length = 225
           
 Score =  454 bits (1156), Expect = e-127
 Identities = 225/225 (100%), Positives = 225/225 (100%)

Query: 1   MIRLPFRDGYYEVRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLP 60
           MIRLPFRDGYYEVRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLP
Sbjct: 1   MIRLPFRDGYYEVRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLP 60

Query: 61  RRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVS 120
           RRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVS
Sbjct: 61  RRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVS 120

Query: 121 KGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTL 180
           KGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTL
Sbjct: 121 KGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTL 180

Query: 181 EPGDIIATGTPPGVGPLRHGDKIEAWVEGIGVLEEEVIAEDSILC 225
           EPGDIIATGTPPGVGPLRHGDKIEAWVEGIGVLEEEVIAEDSILC
Sbjct: 181 EPGDIIATGTPPGVGPLRHGDKIEAWVEGIGVLEEEVIAEDSILC 225


>sp|O58377|Y643_PYRHO HYPOTHETICAL PROTEIN PH0643 >gi|7448782|pir||D71109 probable
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Pyrococcus horikoshii >gi|3257051|dbj|BAA29734.1|
           (AP000003) 230aa long hypothetical
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase
           [Pyrococcus horikoshii]
           Length = 230
           
 Score =  425 bits (1081), Expect = e-118
 Identities = 201/224 (89%), Positives = 217/224 (96%)

Query: 2   IRLPFRDGYYEVRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPR 61
           +RLPFRDGYY+VRPTKI+ALAKNYAEHAREMGSEPPEEP+IFLKPPSALIGP S I+LPR
Sbjct: 7   VRLPFRDGYYDVRPTKIVALAKNYAEHAREMGSEPPEEPIIFLKPPSALIGPGSSIILPR 66

Query: 62  RSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSK 121
           RSKRVDHEVELAVI+GKRAKNVPA KAFDYILGYTI+LDITARDLQAEARKKGYPWT+SK
Sbjct: 67  RSKRVDHEVELAVIMGKRAKNVPASKAFDYILGYTIILDITARDLQAEARKKGYPWTISK 126

Query: 122 GFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLE 181
           GFDTFAPIGPR+VD RELDPSDLEIGLKVNGK+RQLGRTS+MIFKIPELIEYIS IMTLE
Sbjct: 127 GFDTFAPIGPRVVDSRELDPSDLEIGLKVNGKIRQLGRTSQMIFKIPELIEYISHIMTLE 186

Query: 182 PGDIIATGTPPGVGPLRHGDKIEAWVEGIGVLEEEVIAEDSILC 225
           PGDIIATGTPPGVGPLRHGD+IEAW+EGIG +E +V+AEDSILC
Sbjct: 187 PGDIIATGTPPGVGPLRHGDRIEAWIEGIGKMEFDVLAEDSILC 230


>sp|Q59050|YG56_METJA HYPOTHETICAL PROTEIN MJ1656 >gi|2127713|pir||F64506
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase homolog -
           Methanococcus jannaschii >gi|1500558|gb|AAB99677.1|
           (U67606) 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase
           (hpcE) [Methanococcus jannaschii]
           Length = 237
           
 Score =  236 bits (597), Expect = 1e-61
 Identities = 116/210 (55%), Positives = 155/210 (73%), Gaps = 6/210 (2%)

Query: 12  EVRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVE 71
           E++PTKII +  NY +HA+E+  E PE P+IFLKP SA+I     I+ PR SKRVD+EVE
Sbjct: 34  EIKPTKIICVGLNYIDHAKELNMEIPEYPIIFLKPTSAIIYNEDYIIRPRISKRVDYEVE 93

Query: 72  LAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGP 131
           LA++IGK+ KN+  ++A DYI+GYTIL D+TARDLQ    +K   WT +K FDTF PIGP
Sbjct: 94  LAIVIGKKCKNIKKDEANDYIMGYTILNDVTARDLQ----QKDGQWTRAKSFDTFCPIGP 149

Query: 132 RIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTP 191
           RIV  +++DP +L I  +VNG+++Q   T  MIF + EL+E+++SIMTL PGDII+TGTP
Sbjct: 150 RIV--KDIDPMNLNIECRVNGEIKQKSNTKNMIFDVYELVEFVASIMTLYPGDIISTGTP 207

Query: 192 PGVGPLRHGDKIEAWVEGIGVLEEEVIAED 221
           PGVG L+ GD +E  +EGIG+L   V  E+
Sbjct: 208 PGVGELKAGDVVECEIEGIGILRNYVKDEE 237


>pir||A69068 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622625|gb|AAB85982.1| (AE000911)
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase
           [Methanobacterium thermoautotrophicum]
           Length = 260
           
 Score =  218 bits (549), Expect = 5e-56
 Identities = 105/205 (51%), Positives = 145/205 (70%), Gaps = 6/205 (2%)

Query: 13  VRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVEL 72
           V P+K++ +  NY +HA E+G + P+EP+IFLKPP+ +IG    ++ P  S  VD+EVEL
Sbjct: 55  VSPSKVVCVGLNYRDHAAELGMDIPDEPIIFLKPPTTVIGSGDTVIYPEMSSEVDYEVEL 114

Query: 73  AVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPR 132
           A ++ +RA+ V +  A ++I GYT+L D+TARDLQ   R+ G  WT +K FDTF PIGP 
Sbjct: 115 AAVVSERARRVDSSAASEFIAGYTVLNDVTARDLQ---RRDG-QWTRAKSFDTFCPIGP- 169

Query: 133 IVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPP 192
            V + ++ P +L+I LK+NG+VRQ   TS MIF + EL+E+IS +MTLEPGD+IATGTPP
Sbjct: 170 -VIETDVTPDNLDISLKLNGEVRQSSNTSNMIFTVHELLEFISHVMTLEPGDVIATGTPP 228

Query: 193 GVGPLRHGDKIEAWVEGIGVLEEEV 217
           GVG +  GD + A VEG+G L   V
Sbjct: 229 GVGQMVPGDTVRATVEGVGTLVNRV 253


>emb|CAB46032.1| (Z97340) isomerase like protein [Arabidopsis thaliana]
           >gi|7268342|emb|CAB78636.1| (AL161542) isomerase like
           protein [Arabidopsis thaliana]
           Length = 222
           
 Score =  211 bits (531), Expect = 7e-54
 Identities = 108/217 (49%), Positives = 147/217 (66%), Gaps = 7/217 (3%)

Query: 1   MIRLPFRDGYYEVRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLP 60
           MI+  F+ G      TKI+ + +NYA HA+E+G+  P+EPVIFLKP S+ +     I +P
Sbjct: 5   MIQRMFKQG------TKIVCVGRNYAAHAKELGNAVPKEPVIFLKPTSSYLENGGTIEIP 58

Query: 61  RRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVS 120
                + HEVELA++IG++A++VP   A DYI GY + LD+TAR+LQA A+  G PWTV+
Sbjct: 59  HPLDSLHHEVELALVIGQKARDVPESIAMDYIGGYAVALDMTARELQASAKASGLPWTVA 118

Query: 121 KGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTL 180
           KG DTF PI   +      DP +LE+ LKV+G+ RQ G T +MIFK+P LI YISSIMTL
Sbjct: 119 KGQDTFTPISSVLPKAMVRDPDNLELWLKVDGETRQKGLTKDMIFKVPYLISYISSIMTL 178

Query: 181 EPGDIIATGTPPGVGPLRHGDKIEAWVEGIGVLEEEV 217
             GD+I TGTP GVGP++ G KI A + G+  ++ +V
Sbjct: 179 Y-GDVILTGTPEGVGPVKIGQKITAGITGLSEVQFDV 214


>gi|11499807 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-2)
           [Archaeoglobus fulgidus]
           >gi|9789822|sp|O28058|YM25_ARCFU HYPOTHETICAL PROTEIN
           AF2225 >gi|7448784|pir||A69528
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-2)
           homolog - Archaeoglobus fulgidus
           >gi|2648302|gb|AAB89031.1| (AE000952)
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-2)
           [Archaeoglobus fulgidus]
           Length = 250
           
 Score =  208 bits (525), Expect = 3e-53
 Identities = 107/209 (51%), Positives = 143/209 (68%), Gaps = 6/209 (2%)

Query: 13  VRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVEL 72
           V P+KIIA+  NY +HA E+    PEEP++F+KP +A+IG +  I+LP+ S+RVD+E EL
Sbjct: 41  VVPSKIIAVGLNYIDHAEELNMPVPEEPILFMKPSTAVIGHDDCIILPQISQRVDYEGEL 100

Query: 73  AVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPR 132
           AV+I +  +NVP   A DYILGYT   D+TARDLQA    K   WT +K FDTFAP+GP 
Sbjct: 101 AVVIAEDCRNVPETNAADYILGYTCFNDVTARDLQA----KDGQWTRAKSFDTFAPLGPY 156

Query: 133 IVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPP 192
           I +    DPS L I  +VNGKV Q   TS +IF + +L+ ++SS+MTL+ GD+IATGTP 
Sbjct: 157 IAEID--DPSKLGIQTRVNGKVVQKSNTSNLIFDVFQLVSFVSSVMTLKAGDVIATGTPA 214

Query: 193 GVGPLRHGDKIEAWVEGIGVLEEEVIAED 221
           GVG L+ GD +E  +E IG+L    +  D
Sbjct: 215 GVGMLKDGDVVEVEIEKIGILRNTAVKID 243


>pir||D70854 hypothetical protein Rv2993c - Mycobacterium tuberculosis  (strain
           H37RV) >gi|2791590|emb|CAA16078.1| (AL021287)
           hypothetical protein Rv2993c [Mycobacterium
           tuberculosis]
           Length = 239
           
 Score =  206 bits (519), Expect = 2e-52
 Identities = 106/204 (51%), Positives = 138/204 (66%), Gaps = 5/204 (2%)

Query: 16  TKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVI 75
           +K++ + KNYA+H  EMG  PP +PVIFLKP +A+IGPN+ I LP  +  V  E ELA++
Sbjct: 35  SKVVCVGKNYADHIAEMGGRPPADPVIFLKPNTAIIGPNTPIRLPANASPVHFEGELAIV 94

Query: 76  IGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIV- 134
           IG+  K+VPA +A D ILGYTI  D++ARD Q    +    WT +KG DTF P+GP IV 
Sbjct: 95  IGRACKDVPAAQAVDNILGYTIGNDVSARDQQ----QSDGQWTRAKGHDTFCPVGPWIVT 150

Query: 135 DKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGV 194
           D    DP+DLE+   VNG V+Q  RTS MI  I  ++E+IS+IMTL PGD+I TGTP GV
Sbjct: 151 DLAPFDPADLELRTVVNGDVKQHARTSLMIHDIGAIVEWISAIMTLLPGDLILTGTPAGV 210

Query: 195 GPLRHGDKIEAWVEGIGVLEEEVI 218
           GP+  GD +   +EGIG L   V+
Sbjct: 211 GPIEDGDTVSITIEGIGTLTNPVV 234


>gb|AAK42882.1| 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-2) [Sulfolobus
           solfataricus]
           Length = 304
           
 Score =  203 bits (510), Expect = 2e-51
 Identities = 109/214 (50%), Positives = 143/214 (65%), Gaps = 7/214 (3%)

Query: 15  PTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAV 74
           P KI  LA NY  H +E  +EPP+EP IF K  +ALIG N  I+ P+ S +VD+E+EL V
Sbjct: 91  PEKIFLLAVNYKAHGKETNNEPPKEPYIFTKFSNALIGHNQPILYPKASNKVDYEIELGV 150

Query: 75  IIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKK-GYPWTVSKGFDTFAPIGPRI 133
           IIGK+ K V  E+AFDY+ GYT+  DI+ RD Q  +    G  W   KG DT AP+GP I
Sbjct: 151 IIGKQGKYVKRERAFDYVFGYTVFNDISYRDRQFPSEMPYGMRWVHGKGMDTGAPMGPWI 210

Query: 134 VDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPP 192
           V K E+ +P +L + L+VNG+VRQ     +MIFKI E+IEY+S+ +TL+PGDII+TGTPP
Sbjct: 211 VTKDEIPNPYELRLTLRVNGEVRQDAYAEDMIFKIDEIIEYLSNGITLKPGDIISTGTPP 270

Query: 193 GVGP-----LRHGDKIEAWVEGIGVLEEEVIAED 221
           GVG      L+ GD IEA +  IGVL   ++ E+
Sbjct: 271 GVGLATGKFLKPGDTIEAEISKIGVLRNYLVKEE 304


>dbj|BAA95083.1| (AB041600) unnamed protein product [Mus musculus]
           Length = 227
           
 Score =  201 bits (506), Expect = 6e-51
 Identities = 91/193 (47%), Positives = 133/193 (68%)

Query: 18  IIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIG 77
           I+ + +NYA+H +EM S    EPV+FLKP +A     S +++P   + + HEVEL V++G
Sbjct: 23  IVCVGRNYADHVKEMRSTVLSEPVLFLKPSTAYAPEGSPVLMPAYCRNLHHEVELGVLLG 82

Query: 78  KRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKR 137
           KR + +P   A DY+ GY + LD+TARD+Q E +KKG PWT++K F +  P+   +  ++
Sbjct: 83  KRGEAIPEAAAMDYVAGYALCLDMTARDVQEECKKKGLPWTLAKSFTSSCPVSAFVPKEK 142

Query: 138 ELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGPL 197
             DP  L + LKVNG++RQ G+TS MIF IP +I Y+S I+TLE GD+I TGTP GVGP+
Sbjct: 143 IPDPHALRLWLKVNGELRQEGKTSSMIFSIPYIISYVSKIITLEEGDLILTGTPKGVGPI 202

Query: 198 RHGDKIEAWVEGI 210
           +  D+IEA ++G+
Sbjct: 203 KENDEIEAGIDGV 215


>dbj|BAB00076.1| (AB022217) isomerase-like protein [Arabidopsis thaliana]
           Length = 224
           
 Score =  200 bits (503), Expect = 1e-50
 Identities = 100/217 (46%), Positives = 144/217 (66%), Gaps = 6/217 (2%)

Query: 1   MIRLPFRDGYYEVRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLP 60
           MI+  F+ G      TKI+ +  NYA HA+E+G+  P++P++FLKP S+ +     I +P
Sbjct: 5   MIQRLFKQG------TKIVGVGLNYASHAKELGNALPKDPIVFLKPTSSYLENGGTIEIP 58

Query: 61  RRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVS 120
                + HEVELAV+IG++A++VP   A +YI GY + LD+TAR+LQ  A   G P T++
Sbjct: 59  HPLDSLHHEVELAVVIGQKARDVPERLAMNYIGGYALALDMTARELQVSAMASGLPCTLA 118

Query: 121 KGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTL 180
           KG DTF PI   +     LDP++LE+ LKV+ + RQ G T +MIFK+P LI YISS+MTL
Sbjct: 119 KGQDTFTPISSVLPKAMVLDPNNLELWLKVDDETRQKGWTKDMIFKVPYLISYISSVMTL 178

Query: 181 EPGDIIATGTPPGVGPLRHGDKIEAWVEGIGVLEEEV 217
             GD+I TGTP G+GP++ G KI A + G+  ++ +V
Sbjct: 179 FKGDVILTGTPEGIGPVKIGQKITAGITGLSEVQFDV 215


>pir||T29076 hypothetical protein SC1C2.27 - Streptomyces coelicolor
           >gi|3355694|emb|CAA19994.1| (AL031124) hypothetical
           protein SC1C2.27 [Streptomyces coelicolor A3(2)]
           Length = 261
           
 Score =  199 bits (500), Expect = 3e-50
 Identities = 100/207 (48%), Positives = 135/207 (64%), Gaps = 5/207 (2%)

Query: 13  VRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVEL 72
           V P+K++A  +NYAEHARE+G+E P+ P  F KP +++IGP   +  P  ++ + HE EL
Sbjct: 56  VLPSKVVAFGRNYAEHARELGNEVPDAPFAFFKPSTSVIGPGDAVQYPSFTEELHHEAEL 115

Query: 73  AVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPR 132
           AV+IG+  + VP E+  D I GYT   DITARD+Q   ++    W  +KGFD+  P+GP 
Sbjct: 116 AVVIGRMCREVPRERVQDVIFGYTCANDITARDVQRREKQ----WARAKGFDSSCPLGPW 171

Query: 133 IVDKRELDPS-DLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTP 191
           +    +L  + DL + L VNG  RQLGRTSEMI  I +LI  IS  MTL PGD+I TGTP
Sbjct: 172 VETDLDLAAAGDLTVQLTVNGAQRQLGRTSEMIHSIEDLIVNISEAMTLLPGDVILTGTP 231

Query: 192 PGVGPLRHGDKIEAWVEGIGVLEEEVI 218
            GVGPL  GD++   +EGIG L  +V+
Sbjct: 232 AGVGPLNVGDEVAVTIEGIGTLTNKVV 258


>pir||S77124 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxylase/ isomerase -
           Synechocystis sp. (strain PCC 6803)
           >gi|1652763|dbj|BAA17682.1| (D90908)
           5-oxo-1,2,5-tricarboxilic-3-penten acid
           decarboxilase/isomer [Synechocystis sp.]
           Length = 276
           
 Score =  192 bits (482), Expect = 4e-48
 Identities = 101/206 (49%), Positives = 136/206 (65%), Gaps = 7/206 (3%)

Query: 15  PTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAV 74
           P+KI+A+ +NY  HA E+G++ P EP++F KPPSA+      IV P +S+RVD+E ELAV
Sbjct: 57  PSKIVAVGRNYRAHAAELGNDVPAEPLLFFKPPSAIAADQEEIVYPSQSQRVDYEGELAV 116

Query: 75  IIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIV 134
           IIGK+ K++  E+A   I GYTI  DITARDLQ    ++   WT +KGFD F P+GP +V
Sbjct: 117 IIGKQVKDITEEEAASAIWGYTIANDITARDLQ----RQDSQWTRAKGFDGFCPLGPWVV 172

Query: 135 DKRELDP-SDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPG 193
             R +DP + LE  +      RQ    S+M+F  P L+ YIS +MTL PGD+I TGTP G
Sbjct: 173 --RHIDPEAHLETTVNDEETPRQATAISDMVFTPPVLVSYISRVMTLYPGDVILTGTPEG 230

Query: 194 VGPLRHGDKIEAWVEGIGVLEEEVIA 219
           +  L+ GDK+E  +EGIG L   +IA
Sbjct: 231 ISALQVGDKVEVEIEGIGNLTNTIIA 256


>pir||T45421 probable 2-hydroxyhepta-2,4-diene-1,7- dioate isomaerase [imported]
           - Mycobacterium leprae >gi|2414554|emb|CAB16443.1|
           (Z99263) possible 2-hydroxyhepta-2,4-diene-1,7- dioate
           isomaerase [Mycobacterium leprae]
           Length = 242
           
 Score =  192 bits (482), Expect = 4e-48
 Identities = 106/207 (51%), Positives = 139/207 (66%), Gaps = 8/207 (3%)

Query: 16  TKIIALAKNYAEHAREMGSEP---PEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVEL 72
           +K++ + KNYA+H  EMG +      +PVIFLKP +A+IGPN  I LP  +  V  E EL
Sbjct: 35  SKVVCIGKNYADHIVEMGGQTGLASADPVIFLKPNTAIIGPNVPIRLPANASPVHFEGEL 94

Query: 73  AVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPR 132
           A+++G+  K+VPA +A D ILGYTI  D++ARD Q   R  G  WT +KG DTF P+GP 
Sbjct: 95  ALVVGRSCKDVPAVQAVDCILGYTIGNDMSARDQQ---RADGQ-WTRAKGHDTFCPVGPW 150

Query: 133 IV-DKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTP 191
           IV D   LDP+DLE+   VNG+V+Q  RTS MI  I  ++E+IS++MTL PGD+I TGTP
Sbjct: 151 IVTDLGPLDPADLELRTAVNGEVKQHSRTSLMIHGIGAIMEWISAVMTLLPGDLILTGTP 210

Query: 192 PGVGPLRHGDKIEAWVEGIGVLEEEVI 218
            GVGP+  GD +   VEGIG L   V+
Sbjct: 211 AGVGPVEDGDIVSITVEGIGTLTNPVV 237


>pir||E75376 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/
           5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate
           decarboxylase-related protein - Deinococcus radiodurans 
           (strain R1) >gi|6459372|gb|AAF11167.1|AE002004_6
           (AE002004) 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase/5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate
           decarboxylase-related protein [Deinococcus radiodurans]
           Length = 250
           
 Score =  189 bits (476), Expect = 2e-47
 Identities = 95/203 (46%), Positives = 136/203 (66%), Gaps = 9/203 (4%)

Query: 15  PTKIIALAKNYAEHAREMGSEP---PEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVE 71
           P+KI+ + +NY +H RE+G++    P EP IFLK P+AL  P   +  P  S+    E E
Sbjct: 50  PSKIVCVGRNYLDHIRELGNDTGDLPAEPGIFLKGPNALAEPGGTVEYPSWSENFHFEGE 109

Query: 72  LAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGP 131
           LA++IG+RA+N+ A++A   +LGYT  LD+TARD Q    K    W  +K  D F P+GP
Sbjct: 110 LALVIGQRARNLKADEALGAVLGYTCGLDLTARDRQ----KTDLQWFRAKAADRFCPLGP 165

Query: 132 RIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTP 191
            +V   + DPSD+ +  +VNG+ RQ GRTS MIF + +++ Y++  +TLEPGD++ TGTP
Sbjct: 166 WLVT--QFDPSDVRVQTRVNGEPRQDGRTSHMIFDVVQILTYLTRFVTLEPGDVVLTGTP 223

Query: 192 PGVGPLRHGDKIEAWVEGIGVLE 214
            GVGPL+ GD++E  V+GIGVLE
Sbjct: 224 EGVGPLQRGDRVEVEVDGIGVLE 246


>gi|11431155 CGI-105 protein [Homo sapiens]
           Length = 314
           
 Score =  187 bits (471), Expect = 8e-47
 Identities = 91/213 (42%), Positives = 140/213 (65%), Gaps = 10/213 (4%)

Query: 14  RPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELA 73
           RP K++ +  NY +H +E     P+EP+IF K  S+++GP   +VLP +S+ VD EVELA
Sbjct: 104 RPDKVVCVGMNYVDHCKEQNVPVPKEPIIFSKFASSIVGPYDEVVLPPQSQEVDWEVELA 163

Query: 74  VIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRI 133
           V+IGK+ K++ A  A  ++ G+T+  D++ARD Q   R+ G  W + K FDTF P+GP +
Sbjct: 164 VVIGKKGKHIKATDAMAHVAGFTVAHDVSARDWQ--MRRNGKQWLLGKTFDTFCPLGPAL 221

Query: 134 VDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPP 192
           V K  + DP +L+I  +VNG+V Q G T++M+FK  +LI ++S  +T  PGD+I TGTPP
Sbjct: 222 VTKDSVADPHNLKICCRVNGEVVQSGNTNQMVFKTEDLIAWVSQFVTFYPGDVILTGTPP 281

Query: 193 GVGP-------LRHGDKIEAWVEGIGVLEEEVI 218
           GVG        L+ GD+++  +E +GV+  +V+
Sbjct: 282 GVGVFRKPPVFLKKGDEVQCEIEELGVIINKVV 314


>dbj|BAB05724.1| (AP001514) 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase [Bacillus
           halodurans]
           Length = 276
           
 Score =  187 bits (469), Expect = 1e-46
 Identities = 99/209 (47%), Positives = 133/209 (63%), Gaps = 6/209 (2%)

Query: 14  RPTKIIALAKNYAEHAREMGSEPPEEPV-IFLKPPSALIGPNSVIVLPRRSKRVDHEVEL 72
           RP KI+A   NY  H +EM  +     +  FLK  +++IGPN  I+LP  ++R+DHE+EL
Sbjct: 72  RPGKIVAAPVNYMSHKKEMNVDHTARVLGFFLKATTSIIGPNDPIILPYNNRRIDHELEL 131

Query: 73  AVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPR 132
           A +IGKRAK+V  E A DYI GYT L D+T R  +    ++     + K FDTF PIGP 
Sbjct: 132 AFVIGKRAKHVKKENAHDYIFGYTGLNDVTVRPTKNREEER----CLRKSFDTFTPIGPW 187

Query: 133 IVDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTP 191
           IV   E+ DP +L I L+VN +VRQ   T++M+  I EL+E  S +MTLEPGD+IATGTP
Sbjct: 188 IVTSDEIKDPQNLTISLQVNHEVRQHVNTNQMVCGIAELVEIFSHVMTLEPGDLIATGTP 247

Query: 192 PGVGPLRHGDKIEAWVEGIGVLEEEVIAE 220
            GVGP++ GD +   +E IG     V+ E
Sbjct: 248 DGVGPIKDGDTVTLQMESIGSFSNPVVLE 276


>gi|7705608 CGI-105 protein [Homo sapiens] >gi|4929679|gb|AAD34100.1|AF151863_1
           (AF151863) CGI-105 protein [Homo sapiens]
           Length = 314
           
 Score =  186 bits (468), Expect = 2e-46
 Identities = 91/213 (42%), Positives = 140/213 (65%), Gaps = 10/213 (4%)

Query: 14  RPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELA 73
           RP K++ +  NY +H +E     P+EP+IF K  S+++GP   +VLP +S+ VD EVELA
Sbjct: 104 RPDKVVCVGMNYVDHCKEQNVPVPKEPIIFSKFASSIVGPYDEVVLPPQSQEVDWEVELA 163

Query: 74  VIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRI 133
           V+IGK+ K++ A  A  ++ G+T+  D++ARD Q   R+ G  W + K FDTF P+GP +
Sbjct: 164 VVIGKKGKHIKATDAMAHVGGFTVAHDVSARDWQ--MRRNGKQWLLGKTFDTFCPLGPAL 221

Query: 134 VDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPP 192
           V K  + DP +L+I  +VNG+V Q G T++M+FK  +LI ++S  +T  PGD+I TGTPP
Sbjct: 222 VTKDSVADPHNLKICCRVNGEVVQSGNTNQMVFKTEDLIAWVSQFVTFYPGDVILTGTPP 281

Query: 193 GVGP-------LRHGDKIEAWVEGIGVLEEEVI 218
           GVG        L+ GD+++  +E +GV+  +V+
Sbjct: 282 GVGVFRKPPVFLKKGDEVQCEIEELGVIINKVV 314


>pir||C75575 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/
           5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase
           - Deinococcus radiodurans (strain R1)
           >gi|6460702|gb|AAF12407.1|AE001863_32 (AE001863)
           2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase/5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate
           decarboxylase [Deinococcus radiodurans]
           Length = 262
           
 Score =  185 bits (466), Expect = 3e-46
 Identities = 96/208 (46%), Positives = 136/208 (65%), Gaps = 4/208 (1%)

Query: 15  PTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAV 74
           P K+IALA NYA+H  E+G + PEEPV+FLKP ++L+     ++ PR +K + +EVEL +
Sbjct: 44  PGKVIALALNYADHVAELGFKAPEEPVMFLKPNTSLLPHQGTVIYPRGAKFMHYEVELGI 103

Query: 75  IIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIV 134
           +IG+ A+ V A+ A DY+ GYTI  D+  RD  +   +   P   +KG+DTF P+GP +V
Sbjct: 104 VIGRDARRVKAKDADDYVGGYTIANDLVVRDYVSNYYR---PPMRAKGWDTFGPLGPYLV 160

Query: 135 DKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPG 193
              E+ DP +L +   VNG++RQ G T +MI K PELIE++S  MTLE GD+I TGTP G
Sbjct: 161 SADEVPDPYNLGLRAYVNGELRQEGSTRDMILKAPELIEFMSRFMTLEAGDVILTGTPKG 220

Query: 194 VGPLRHGDKIEAWVEGIGVLEEEVIAED 221
           V  +  GD +   ++G+G LE  V  ED
Sbjct: 221 VSHVHPGDVMRLEIDGLGALENPVALED 248


>pir||C71425 hypothetical protein - Arabidopsis thaliana
           Length = 367
           
 Score =  183 bits (461), Expect = 1e-45
 Identities = 95/188 (50%), Positives = 127/188 (67%), Gaps = 7/188 (3%)

Query: 1   MIRLPFRDGYYEVRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLP 60
           MI+  F+ G      TKI+ + +NYA HA+E+G+  P+EPVIFLKP S+ +     I +P
Sbjct: 5   MIQRMFKQG------TKIVCVGRNYAAHAKELGNAVPKEPVIFLKPTSSYLENGGTIEIP 58

Query: 61  RRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVS 120
                + HEVELA++IG++A++VP   A DYI GY + LD+TAR+LQA A+  G PWTV+
Sbjct: 59  HPLDSLHHEVELALVIGQKARDVPESIAMDYIGGYAVALDMTARELQASAKASGLPWTVA 118

Query: 121 KGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTL 180
           KG DTF PI   +      DP +LE+ LKV+G+ RQ G T +MIFK+P LI YISSIMTL
Sbjct: 119 KGQDTFTPISSVLPKAMVRDPDNLELWLKVDGETRQKGLTKDMIFKVPYLISYISSIMTL 178

Query: 181 EPGDIIAT 188
             GD+I T
Sbjct: 179 Y-GDVILT 185


>pir||T03559 2-hydroxyhepta-2,4-diene-1, 7-dioateisomerase/
           5-carboxymethyl-2-oxo-hex-3-ene-1, 7-dioatedecarboxylase
           - Rhodobacter capsulatus >gi|3128360|gb|AAC16212.1|
           (AF010496)
           2-hydroxyhepta-2,4-diene-1,
           7-dioateisomerase/5-carboxymethyl-2-oxo-hex-3-ene-1,
           7-dioatedecarboxylase [Rhodobacter capsulatus]
           Length = 280
           
 Score =  182 bits (457), Expect = 3e-45
 Identities = 97/210 (46%), Positives = 129/210 (61%), Gaps = 11/210 (5%)

Query: 17  KIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVII 76
           K+IA+  NYA+HA E G   P EPV+F+K  SA+ GP+  +  PR S+++D EVELA +I
Sbjct: 72  KLIAIGLNYADHAEEAGLTVPPEPVVFMKATSAICGPDDDVEAPRGSEKLDWEVELAFVI 131

Query: 77  GKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDK 136
           G RAK V  E A D++ GY I  D++ R  Q E   +   W   K  DTFAP+GP +V K
Sbjct: 132 GTRAKYVTLEDAMDHVAGYMICNDVSERSFQIE---RSGQWVKGKSHDTFAPLGPWLVTK 188

Query: 137 REL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVG 195
            E+ DP  L++ L VNG  RQ G T+ M++ +  L+ Y+S  MTLEPGDII TGTPPGVG
Sbjct: 189 DEIKDPQALDLWLNVNGVRRQTGTTATMVYGVAFLVHYLSQFMTLEPGDIITTGTPPGVG 248

Query: 196 P-------LRHGDKIEAWVEGIGVLEEEVI 218
                   L  GD IE  + G+G   + V+
Sbjct: 249 MGSRPPKFLHAGDVIELGITGLGSQRQVVV 278


>dbj|BAB05719.1| (AP001514) 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase [Bacillus
           halodurans]
           Length = 319
           
 Score =  175 bits (440), Expect = 3e-43
 Identities = 95/209 (45%), Positives = 129/209 (61%), Gaps = 12/209 (5%)

Query: 17  KIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVII 76
           KII +  NY EH  EM  E P+ PVIF K  + +IGP   + LP  ++++D+E ELA +I
Sbjct: 103 KIICVGHNYREHILEMKREIPKYPVIFAKFANTIIGPEDNVPLPSITEQLDYEAELAFVI 162

Query: 77  GKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDK 136
           GK+AK+V  E A DY+ GYTI+ DITARDLQ    ++   W   K  D   P+GP +V K
Sbjct: 163 GKKAKDVAKEDALDYVAGYTIVNDITARDLQ----RRTIQWLQGKTLDGSLPMGPWLVTK 218

Query: 137 REL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVG 195
            E+ +P  LEI L VNG+ RQ   T  ++F I +L+ ++S IMTLEPGD++ TGTP GVG
Sbjct: 219 DEIPNPHQLEITLSVNGEERQRSNTKNLVFSIQDLVVFLSGIMTLEPGDVVCTGTPGGVG 278

Query: 196 P-------LRHGDKIEAWVEGIGVLEEEV 217
                   L+ GD +   +E +G LE  V
Sbjct: 279 VAREPQLFLQDGDVVRIELEKVGTLENRV 307


>pir||C69837 5-oxo-1,2,5-tricarboxilic-3-penten acid de homolog yisK - Bacillus
           subtilis >gi|2145376|emb|CAA70682.1| (Y09476) YisK
           [Bacillus subtilis] >gi|2633411|emb|CAB12915.1| (Z99109)
           similar to 5-oxo-1,2,5-tricarboxilic-3-penten acid
           decarboxylase [Bacillus subtilis]
           Length = 301
           
 Score =  173 bits (435), Expect = 1e-42
 Identities = 98/216 (45%), Positives = 136/216 (62%), Gaps = 16/216 (7%)

Query: 14  RPTK-IIALAKNYAEHAREMGSEP--PEEPVIFLKPPSALIGPNSVIVLPRR-SKRVDHE 69
           +P+K II + KNY +HA EMGSE   PE P++F K P  + G   ++      + ++D+E
Sbjct: 89  KPSKNIICIGKNYRDHAIEMGSEADIPEHPMVFTKSPVTVTGHGDIVKSHEEVTSQLDYE 148

Query: 70  VELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPI 129
            ELAV+IGK    +  E A+D++ GYTI+ DITARDLQ    K+   + + K  DT  P+
Sbjct: 149 GELAVVIGKSGTRISKEDAYDHVFGYTIVNDITARDLQ----KRHKQFFIGKSLDTTCPM 204

Query: 130 GPRIVDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIAT 188
           GP +V K  + +P  L++  +VNG++RQ G  S+MIF IPELIE +S  MTLE GDIIAT
Sbjct: 205 GPVLVHKSSIQEPERLKVETRVNGELRQSGSASDMIFSIPELIETLSKGMTLEAGDIIAT 264

Query: 189 GTPPGVGP-------LRHGDKIEAWVEGIGVLEEEV 217
           GTP GVG        LR GDKI+  ++ IG L  ++
Sbjct: 265 GTPSGVGKGFTPPKFLRSGDKIDITIDPIGTLSNQI 300


>gb|AAG19447.1| (AE005037) 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; HpcE
           [Halobacterium sp. NRC-1]
           Length = 244
           
 Score =  173 bits (435), Expect = 1e-42
 Identities = 86/206 (41%), Positives = 128/206 (61%), Gaps = 6/206 (2%)

Query: 15  PTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAV 74
           P+K++ + +NYA HA E  ++ P+ P++FLKPP+A+ G      LP  + RV+HE ELAV
Sbjct: 42  PSKVVCVGRNYAAHADERDADVPDRPLLFLKPPTAVAGHGDATPLPPNT-RVEHEAELAV 100

Query: 75  IIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIV 134
           +IG +A+N+ A  A   + GYT+  D++ R  Q   +     W   K FD   P+GP + 
Sbjct: 101 VIGTQARNLDAGAAMAAVEGYTVANDVSNRTDQDREQN----WVRGKAFDGSCPLGPVVA 156

Query: 135 DKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGV 194
              E+ P D  + L VNG+ RQ G  S+ +F +P L+  I++ +TL+PGD++ TGTPPGV
Sbjct: 157 TPDEV-PDDATVALDVNGERRQSGSISQFVFDVPTLLAEITAFVTLQPGDVVLTGTPPGV 215

Query: 195 GPLRHGDKIEAWVEGIGVLEEEVIAE 220
           G L  GD++ A VEG+G LE  V+ E
Sbjct: 216 GELTDGDRVAASVEGVGTLEHTVVRE 241


>emb|CAB65580.1| (AL136058) putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase.
           [Streptomyces coelicolor A3(2)]
           Length = 285
           
 Score =  170 bits (427), Expect = 1e-41
 Identities = 89/211 (42%), Positives = 130/211 (61%), Gaps = 13/211 (6%)

Query: 17  KIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVII 76
           KI+ +  NY +HARE G+EPP EPV+F K P  ++GP+  +++PR S + D EVELAV+I
Sbjct: 75  KIVCIGLNYHDHARETGAEPPAEPVVFFKAPDTVVGPHDTVLVPRGSTKTDWEVELAVVI 134

Query: 77  GKRAKNV-PAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVD 135
           G+ A+ +  AE+    + GY +  D++ R+ Q E   +G  W   K  +TF P+GP +V 
Sbjct: 135 GRTARYLESAEEGLACVAGYAVAHDVSEREFQIE---RGGTWDKGKNCETFNPLGPWLVT 191

Query: 136 KREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGV 194
             E+ DP  L + L VNG+++Q G T+E IF + E++ Y+S  M L PGDII TGTP GV
Sbjct: 192 ADEVPDPQRLPLRLWVNGELKQDGTTAEQIFPVGEVVRYLSRFMVLRPGDIINTGTPAGV 251

Query: 195 GP--------LRHGDKIEAWVEGIGVLEEEV 217
                     LR GD +E  +EG+G   +E+
Sbjct: 252 AMGQPEPKPYLRAGDVVELEIEGLGRQRQEL 282


>sp|P34673|YO23_CAEEL HYPOTHETICAL 23.3 KDA PROTEIN ZK688.3 IN CHROMOSOME III
           >gi|630783|pir||S44919 ZK688.3 protein - Caenorhabditis
           elegans >gi|289782|gb|AAA28230.1| (L16621) coded for by
           C. elegans cDNAs GenBank:T01366 and T00450; putative
           [Caenorhabditis elegans]
           Length = 214
           
 Score =  168 bits (422), Expect = 4e-41
 Identities = 84/189 (44%), Positives = 118/189 (61%)

Query: 16  TKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVI 75
           TKI+ + +NY +HA E+G+  P++P++F+K  ++ I     IV P   + +  EVEL V+
Sbjct: 12  TKIVCVGRNYKDHALELGNAIPKKPMLFVKTVNSFIVEGEPIVAPPGCQNLHQEVELGVV 71

Query: 76  IGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVD 135
           I K+A  +    A DYI GYT+ LD+TARD Q EA+K G PW ++K FD   PIG  +  
Sbjct: 72  ISKKASRISKSDAMDYIGGYTVALDMTARDFQDEAKKAGAPWFLAKSFDGSCPIGGFLPV 131

Query: 136 KRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVG 195
               +P D+E+  K+NGK +Q  RT  MIF IP L+EY +   TLE GD++ TGTP GV 
Sbjct: 132 SDIPNPHDVELFCKINGKDQQRCRTDVMIFDIPTLLEYTTQFFTLEVGDVVLTGTPAGVT 191

Query: 196 PLRHGDKIE 204
            +  GD IE
Sbjct: 192 KINSGDVIE 200


>gb|AAF55854.1| (AE003733) CG5793 gene product [Drosophila melanogaster]
           Length = 220
           
 Score =  167 bits (419), Expect = 9e-41
 Identities = 85/204 (41%), Positives = 123/204 (59%)

Query: 17  KIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVII 76
           KI+ +A NY +         P+EP++FLKP S+ +     IVLP+   +V +EVEL V+I
Sbjct: 17  KIVGVALNYMDVVLARNVPVPKEPLVFLKPTSSYLQEGQPIVLPKVFTKVAYEVELGVVI 76

Query: 77  GKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDK 136
           GK  KNV    A  Y+ GY + LD+TA+     AR  G+PWT+ KGFDT  P+   I  +
Sbjct: 77  GKPCKNVSKADAMSYVAGYCLALDLTAQCNLGPARAAGHPWTLGKGFDTSTPVSQFIPIE 136

Query: 137 RELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGP 196
           +  DP +L + L VNG ++Q G T+++IFK+P++I Y+S  MTLE  D+I TGTP G   
Sbjct: 137 KVTDPHNLPLWLTVNGDLKQNGCTADLIFKVPDIISYVSKYMTLEANDLILTGTPNGADA 196

Query: 197 LRHGDKIEAWVEGIGVLEEEVIAE 220
            + GD I+  +  +  L  +V AE
Sbjct: 197 FKAGDVIQCGMADLAKLTFQVEAE 220


>emb|CAB55708.1| (AL117387) putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase
           [Streptomyces coelicolor A3(2)]
           Length = 292
           
 Score =  166 bits (416), Expect = 2e-40
 Identities = 88/206 (42%), Positives = 127/206 (60%), Gaps = 10/206 (4%)

Query: 14  RPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELA 73
           RP  ++ + +NYA HA E GSEPP  PVIF KPP+ ++GPN  + +PR S R D EVELA
Sbjct: 71  RPGAVVCIGQNYAAHAAESGSEPPTRPVIFFKPPNTVVGPNDEVEIPRGSARTDWEVELA 130

Query: 74  VIIGKRAKNVPAE-KAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPR 132
           V+IG+ A+ + +  +A +++ GY +  D++ RD Q E    G  W+  K   TF P+GP 
Sbjct: 131 VVIGRTARYLDSPGQALEHVAGYAVSNDVSERDFQLE--HSGGQWSKGKSCATFNPLGPF 188

Query: 133 IVDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTP 191
           +V   E+ D   L +   VNG+ RQ  RT++MIF + +L+  +S  + L+PGD+I TGTP
Sbjct: 189 LVPADEVPDVQALRLRSFVNGEPRQDSRTADMIFSVAQLVYDLSQYLVLDPGDVINTGTP 248

Query: 192 PGVG------PLRHGDKIEAWVEGIG 211
            GV        LR GD +E  +EG+G
Sbjct: 249 EGVALSGRFPYLRPGDVMEIEIEGLG 274


>sp|P76004|YCGM_ECOLI PROTEIN YCGM >gi|7448786|pir||A64864 probable
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase b1180 -
           Escherichia coli >gi|1787428|gb|AAC74264.1| (AE000216)
           putative isomerase [Escherichia coli K12]
           >gi|4062757|dbj|BAA36014.1| (D90751) ZK688.3 protein
           [Escherichia coli] >gi|4062767|dbj|BAA36027.1| (D90752)
           ZK688.3 protein [Escherichia coli]
           Length = 219
           
 Score =  165 bits (414), Expect = 4e-40
 Identities = 83/195 (42%), Positives = 117/195 (59%), Gaps = 1/195 (0%)

Query: 16  TKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVI 75
           +K++ +  NYA+H +EMGS  PEEPV+F+KP +AL      + +P     V HEVELAV+
Sbjct: 17  SKVVCVGSNYAKHIKEMGSAVPEEPVLFIKPETALCDLRQPLAIPSDFGSVHHEVELAVL 76

Query: 76  IGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRI-V 134
           IG   +    E     I GY + LD+T RD+Q + +K G PW  +K FD   P+   I  
Sbjct: 77  IGATLRQATEEHVRKAIAGYGVALDLTLRDVQGKMKKAGQPWEKAKAFDNSCPLSGFIPA 136

Query: 135 DKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGV 194
            +   DP +  + L VNG+ RQ G T++MI KI  LI Y+S   TL+ GD++ TGTP GV
Sbjct: 137 AEFTGDPQNTTLSLSVNGEQRQQGTTADMIHKIVPLIAYMSKFFTLKAGDVVLTGTPDGV 196

Query: 195 GPLRHGDKIEAWVEG 209
           GPL+ GD++    +G
Sbjct: 197 GPLQSGDELTVTFDG 211


>sp|Q46978|HPAG_ECOLI 4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL
           ISOMERASE/DECARBOXYLASE [INCLUDES:
           2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE (HHDD
           ISOMERASE); 5-CARBOXYMETHYL-2-OXO-HEX-3-ENE-1,7-DIOATE
           DECARBOXYLASE (OPET DECARBOXYLASE)]
           >gi|757826|emb|CAA86040.1| (Z37980)
           5-oxo-1,2,5-tricarboxilic-3-penten acid
           decarboxilase/isomer [Escherichia coli]
           Length = 429
           
 Score =  164 bits (410), Expect = 1e-39
 Identities = 86/206 (41%), Positives = 124/206 (59%), Gaps = 4/206 (1%)

Query: 18  IIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIG 77
           + AL  NYA+HA E+  +PPEEP++FLK P+ L G N   V P   + + +E EL V+IG
Sbjct: 225 LFALGLNYADHASELEFKPPEEPLVFLKAPNTLTGDNQTSVRPNNIEYMHYEAELVVVIG 284

Query: 78  KRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKR 137
           K+A+NV    A DY+ GYT+  D   RD      +   P    K  D   P+   IV K 
Sbjct: 285 KQARNVSEADAMDYVAGYTVCNDYAIRDYLENYYR---PNLRVKSRDGLTPMLSTIVPKE 341

Query: 138 EL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGP 196
            + DP +L +   VNG++RQ G T+++IF +P LI Y+S  MTL PGD+IATGTP G+  
Sbjct: 342 AIPDPHNLTLRTFVNGELRQQGTTADLIFSVPFLIAYLSEFMTLNPGDMIATGTPKGLSD 401

Query: 197 LRHGDKIEAWVEGIGVLEEEVIAEDS 222
           +  GD++   VEG+G L   +++E++
Sbjct: 402 VVPGDEVVVEVEGVGRLVNRIVSEET 427


 Score = 81.5 bits (198), Expect = 8e-15
 Identities = 58/188 (30%), Positives = 91/188 (47%), Gaps = 9/188 (4%)

Query: 36  PPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGY 95
           PP+  V F+KP + +IG    I  P+  K V     +A+I+GK A  V  E A +YI GY
Sbjct: 31  PPKTAVWFIKPRNTVIGCGEPIPFPQGEK-VLSGATVALIVGKTATKVREEDAAEYIAGY 89

Query: 96  TILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVR 155
            +  D++   L  E+  +  P   +K  D F PIG  +      +  +L I  ++NG+  
Sbjct: 90  ALANDVS---LPEESFYR--PAIKAKCRDGFCPIGETVALS---NVDNLTIYTEINGRPA 141

Query: 156 QLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGPLRHGDKIEAWVEGIGVLEE 215
               T+++     +L+  +S   TL PGD I  GTP     ++ GD++    EG   LE 
Sbjct: 142 DHWNTADLQRNAAQLLSALSEFATLNPGDAILLGTPQARVEIQPGDRVRVLAEGFPPLEN 201

Query: 216 EVIAEDSI 223
            V+ E  +
Sbjct: 202 PVVDEREV 209


>sp|Q9RPU5|HPAG_SALDU 4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL
           ISOMERASE/DECARBOXYLASE [INCLUDES:
           2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE (HHDD
           ISOMERASE); 5-CARBOXYMETHYL-2-OXO-HEX-3-ENE-1,7-DIOATE
           DECARBOXYLASE (OPET DECARBOXYLASE)]
           >gi|5833401|gb|AAD53501.1|AF144422_8 (AF144422) HpaG
           [Salmonella dublin]
           Length = 429
           
 Score =  161 bits (402), Expect = 9e-39
 Identities = 83/206 (40%), Positives = 124/206 (59%), Gaps = 4/206 (1%)

Query: 18  IIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIG 77
           + AL  NYA+HA E+   PP+EP++F+K P+     +   V P   + + +E EL V+IG
Sbjct: 225 LFALGLNYADHASELAFTPPKEPLVFIKAPNTFTEHHQTSVRPNNVEYMHYEAELVVVIG 284

Query: 78  KRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKR 137
           K A+ V   +A +Y+ GYT+  D   RD      +   P    K  D   PIGP IVDK 
Sbjct: 285 KTARKVSEAEAMEYVAGYTVCNDYAIRDYLENYYR---PNLRVKSRDGLTPIGPWIVDKE 341

Query: 138 EL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGP 196
            + DP +L +   VNG++RQ G T+++IF IP LI Y+S  MTL+PGD+IATGTP G+  
Sbjct: 342 AVSDPHNLTLRTFVNGELRQEGTTADLIFSIPFLISYLSEFMTLQPGDMIATGTPKGLSD 401

Query: 197 LRHGDKIEAWVEGIGVLEEEVIAEDS 222
           +  GD++   ++G+G L  +++ E+S
Sbjct: 402 VVPGDEVVLEIKGVGRLVNQIVCEES 427


 Score = 81.5 bits (198), Expect = 8e-15
 Identities = 58/186 (31%), Positives = 92/186 (49%), Gaps = 9/186 (4%)

Query: 36  PPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGY 95
           PP+  V F+KP + +I     I+ P+  K V     +A+I+GK A    +E A +YI GY
Sbjct: 31  PPKTAVWFIKPRNTVIRHGEPILYPQGEK-VLSGATVALIVGKTASRKRSEAAAEYIAGY 89

Query: 96  TILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVR 155
            +  +++   L  E+  +  P   +K  D F P+G         D  +L I  ++NG+  
Sbjct: 90  ALANEVS---LPEESFYR--PAIKAKCRDGFCPLGEMAPLS---DVDNLTIITEINGREA 141

Query: 156 QLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGPLRHGDKIEAWVEGIGVLEE 215
               T+++     +L+  +S   TL PGD I  GTP     LR GD++    +G+  LE 
Sbjct: 142 DHWNTADLQRSAAQLLSALSEFATLNPGDAILLGTPQNRVALRPGDRVRILAKGLPALEN 201

Query: 216 EVIAED 221
            V+AED
Sbjct: 202 PVVAED 207


>emb|CAC12279.1| (AL445066) 2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase related
           protein [Thermoplasma acidophilum]
           Length = 250
           
 Score =  159 bits (399), Expect = 2e-38
 Identities = 86/212 (40%), Positives = 124/212 (57%), Gaps = 8/212 (3%)

Query: 13  VRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVEL 72
           V P KI   A N+  H++E  ++ P +P  F K  +AL+G N     PR  +++D+E E+
Sbjct: 34  VNPGKIFLPAVNFRSHSQESDTKFPPKPYFFTKFSNALVGHNGTAHRPREIEKLDYEGEI 93

Query: 73  AVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQ-AEARKKGYPWTVSKGFDTFAPIGP 131
            ++IGKR K +  E+A +YI G+TI+ D++ARD Q  E    GY W   K FD   P+GP
Sbjct: 94  GIVIGKRGKRIGVEEAQNYIFGFTIVDDVSARDYQFPEMHPYGYNWVQGKAFDEALPVGP 153

Query: 132 RIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTP 191
            IV + E+    L+I  +VNG++RQ G T +M+F + +LI  +S  +TLEPGD+I TGTP
Sbjct: 154 YIVTRDEI-RFPLKIETRVNGELRQSGTTEDMVFSVEQLISTVSQTITLEPGDLITTGTP 212

Query: 192 PGVGP------LRHGDKIEAWVEGIGVLEEEV 217
            GV        L  GD +   V GIG L   +
Sbjct: 213 AGVAAFTEAKYLSDGDTVSISVSGIGELVHRI 244


>gb|AAF55945.1| (AE003737) CG6028 gene product [Drosophila melanogaster]
           Length = 288
           
 Score =  159 bits (399), Expect = 2e-38
 Identities = 87/214 (40%), Positives = 126/214 (58%), Gaps = 12/214 (5%)

Query: 15  PTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAV 74
           P KII +  NY +H  E     P+EP+ F K  +AL+GP   ++    S ++D EVEL  
Sbjct: 77  PGKIICIGLNYQDHCDEQNKPTPKEPLFFSKFNNALVGPQDNVIAHAASSKIDWEVELVC 136

Query: 75  IIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIV 134
           +IGK A+ VP  +A DY+ GY++  DI+ARD Q E  + G  + + K  DTF P+GP +V
Sbjct: 137 VIGKVARQVPKSQAMDYVFGYSVAQDISARDWQKE--RNGGQFLMGKSMDTFLPLGPAVV 194

Query: 135 DKRELDPSDLEIGLK--VNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPP 192
            K  L P    + LK  VNG  +Q G T  +IFK+ ++I  +S  +TL PGDII TGTP 
Sbjct: 195 HK-SLVPDVYNLNLKTWVNGVEKQNGNTGNLIFKLDDVINRLSQTITLLPGDIIVTGTPK 253

Query: 193 GVGP-------LRHGDKIEAWVEGIGVLEEEVIA 219
           GVG        L+ GD +++ + G+G L  +++A
Sbjct: 254 GVGMHRTPPEFLQPGDVVQSEIVGLGKLCNKIVA 287


>pir||G83604 conserved hypothetical protein PA0318 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9946165|gb|AAG03707.1|AE004470_1 (AE004470)
           conserved hypothetical protein [Pseudomonas aeruginosa]
           Length = 221
           
 Score =  159 bits (397), Expect = 4e-38
 Identities = 78/203 (38%), Positives = 126/203 (61%), Gaps = 1/203 (0%)

Query: 17  KIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVII 76
           K++ + +NYAEHA+E+ +  P EP++F+KP S ++  +  + LP+    V +E E+AV+I
Sbjct: 19  KLVCVGRNYAEHAKELNNPVPTEPLLFIKPGSCVVPVSGGLSLPQERGSVHYEAEIAVLI 78

Query: 77  GKRAKNVP-AEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVD 135
           GK     P  E+  D I GY   LD+T R++QA+ ++KG PW ++K FD    + P +  
Sbjct: 79  GKPLSRKPNREEVLDAISGYAPALDLTLREVQAKLKEKGLPWELAKSFDGAGVLSPFVNA 138

Query: 136 KRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVG 195
            +  DP+D+ I L +NG+VRQ G + +M+  I  LI++I+   +L+ GD++ TGTP GVG
Sbjct: 139 DQFPDPTDIGIRLTINGEVRQDGNSRDMLNPIVPLIQHIAGHFSLQAGDVVLTGTPSGVG 198

Query: 196 PLRHGDKIEAWVEGIGVLEEEVI 218
           PL  GD++   + G    E  V+
Sbjct: 199 PLNSGDELLLELPGASRFETRVL 221


>pir||G83131 conserved hypothetical protein PA4122 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9950325|gb|AAG07509.1|AE004828_10 (AE004828)
           conserved hypothetical protein [Pseudomonas aeruginosa]
           Length = 259
           
 Score =  156 bits (391), Expect = 2e-37
 Identities = 87/204 (42%), Positives = 118/204 (57%), Gaps = 4/204 (1%)

Query: 18  IIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIG 77
           + AL  NYA+HA E+  + P EP+ FLK P    G   V   P     + +E EL  +IG
Sbjct: 46  MFALGLNYADHAAELSFKAPSEPLAFLKSPGTYTGHRQVSWRPDNVDYMHYECELVAVIG 105

Query: 78  KRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKR 137
           K A+NV  E A  Y+ GYT+  D   RD      +   P    K  D   P+GP IVD  
Sbjct: 106 KPARNVRREDALGYLAGYTVCNDYAIRDYLENYYR---PNLRVKNRDATTPVGPWIVDAA 162

Query: 138 EL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGP 196
           E+ +P+ L +   VNG++RQ G T++MIF IP LIEY SS MTL+PGD+IATGTP G+  
Sbjct: 163 EVPEPNRLTLRTWVNGELRQEGSTADMIFDIPYLIEYFSSFMTLQPGDMIATGTPEGLSD 222

Query: 197 LRHGDKIEAWVEGIGVLEEEVIAE 220
           +  GD++   VEG+G L   +++E
Sbjct: 223 VVPGDEVVVEVEGVGRLVNRIVSE 246


>gi|6324161 Ynl168cp [Saccharomyces cerevisiae]
           >gi|1730800|sp|P53889|YNQ8_YEAST HYPOTHETICAL 28.8 KDA
           PROTEIN IN PSD1-SKO1 INTERGENIC REGION
           >gi|2131905|pir||S60959 hypothetical protein YNL168c -
           yeast (Saccharomyces cerevisiae)
           >gi|1050785|emb|CAA63271.1| (X92517) N1696
           [Saccharomyces cerevisiae] >gi|1302142|emb|CAA96055.1|
           (Z71444) ORF YNL168c [Saccharomyces cerevisiae]
           Length = 259
           
 Score =  156 bits (390), Expect = 2e-37
 Identities = 89/221 (40%), Positives = 133/221 (59%), Gaps = 36/221 (16%)

Query: 17  KIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSV-------------------- 56
           KII + +NYA H +E+ +  P++P  FLKP S+++ P S                     
Sbjct: 11  KIICIGRNYAAHIKELNNSTPKQPFFFLKPTSSIVTPLSSSLVKTTRPANSTFNGLNEDG 70

Query: 57  -----IVLPRRSKRVDHEVELAVIIGKRAKNVPA---EKAFDYILGYTILLDITARDLQA 108
                I +PR  K V HE+ELA+I+ K   NV     E+ +D I G  + LD+TAR++Q 
Sbjct: 71  TNPGPIFIPRGVK-VHHEIELALIVSKHLSNVTKMKPEEVYDSISGVALALDLTARNVQD 129

Query: 109 EARKKGYPWTVSKGFDTFAPIGPRIVDKRELD--PSDLE----IGLKVNGKVRQLGRTSE 162
           EA+KKG PWT+SKGFDTF PI   IV + +     S+L+    +   VNG++RQ G T+ 
Sbjct: 130 EAKKKGLPWTISKGFDTFMPIS-AIVSREKFSSYKSNLQDIFRVKCSVNGQLRQDGGTNL 188

Query: 163 MIFKIPELIEYISSIMTLEPGDIIATGTPPGVGPLRHGDKI 203
           M+  + +++++IS++++LEPGDII TGTP GVG L+ GD++
Sbjct: 189 MLHPLHKILQHISTMISLEPGDIILTGTPAGVGELKPGDRV 229


>pir||T50353 homolog to prokaryotic 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase [imported] - fission yeast
           (Schizosaccharomyces pombe) >gi|7106074|emb|CAB76045.1|
           (AL157918) similar to prokaryotic
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase
           [Schizosaccharomyces pombe]
           Length = 221
           
 Score =  152 bits (380), Expect = 4e-36
 Identities = 82/208 (39%), Positives = 125/208 (59%), Gaps = 5/208 (2%)

Query: 14  RPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELA 73
           R  K++ + +NYA H RE+ +  P +P  FLKP SA++ P    ++        +EVEL 
Sbjct: 4   RAGKVVCIGRNYAAHIRELNNPFPTKPFFFLKPTSAIVEPGHGNLIIPPDVSAHYEVELG 63

Query: 74  VIIGKRA---KNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIG 130
           +I+  R    + V +    D I  Y + +D+TAR++Q EA+KKG PW+ +KG+DTF P+G
Sbjct: 64  LIMKDRLPARRPVSSNSWLDSIGAYFVGIDMTARNIQNEAKKKGLPWSFAKGYDTFLPVG 123

Query: 131 PRIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGT 190
           P I      DP ++ + L +NGKV Q   TS M+ KIP++   I+  M+L PGD++ TGT
Sbjct: 124 PIIPKHLIPDPHNVILELSLNGKVVQKDSTSLMLNKIPKIFSSITEAMSLNPGDLVLTGT 183

Query: 191 PPGVGPLRHGDKIEAWVEGIGVLEEEVI 218
           P GVGP+  GD + A +  +   E+E+I
Sbjct: 184 PKGVGPVVPGDILSARL--LTAQEQEII 209


>pir||A83338 conserved hypothetical protein PA2471 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9948521|gb|AAG05859.1|AE004674_9 (AE004674)
           conserved hypothetical protein [Pseudomonas aeruginosa]
           Length = 232
           
 Score =  152 bits (379), Expect = 5e-36
 Identities = 75/207 (36%), Positives = 117/207 (56%), Gaps = 5/207 (2%)

Query: 17  KIIALAKNYAEHAREMGSEPPEEPVIFL-KPPSALI----GPNSVIVLPRRSKRVDHEVE 71
           ++  + +NYA HAREMG +P  EP  F  KP  A++    G    +  P ++    +E+E
Sbjct: 26  RVYCVGRNYAAHAREMGFDPEREPPFFFCKPADAVVPVAAGSTLELAYPSQTGNYHYEIE 85

Query: 72  LAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGP 131
           L   IGK   ++P E+A +++ GY + LD+T RDLQ   R+ G PW + K FD  APIGP
Sbjct: 86  LVAAIGKGGCDIPLEQAEEHVWGYAVGLDMTRRDLQMRMREMGRPWEIGKAFDRSAPIGP 145

Query: 132 RIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTP 191
                +   P    I L+V+G+ RQ     ++I+ + E + Y+S    L PGD++ TGTP
Sbjct: 146 LYPASQVGHPRHAAISLQVDGEDRQRSDIDQLIWSVAETVSYLSRFFELRPGDLVFTGTP 205

Query: 192 PGVGPLRHGDKIEAWVEGIGVLEEEVI 218
            GVG +  G+++   ++G+G L   V+
Sbjct: 206 EGVGAVERGERMLGAIDGLGELSVRVV 232


>emb|CAC11884.1| (AL445065) probable 2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase
           [Thermoplasma acidophilum]
           Length = 315
           
 Score =  152 bits (379), Expect = 5e-36
 Identities = 90/215 (41%), Positives = 122/215 (55%), Gaps = 19/215 (8%)

Query: 13  VRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVEL 72
           +R  KI+ +  NY EHA+E   +  E P IF K   ++IG    I +P+ +K++D+E EL
Sbjct: 109 LRSGKILCIGVNYMEHAKESRQKVMEHPTIFCKFQDSIIGNMDDITVPKDAKQIDYEGEL 168

Query: 73  AVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPR 132
            VIIG+ +    +      I GYTI  D++ARDLQ    +    W + K   TFAPIGP 
Sbjct: 169 VVIIGRSSGTAESS-----IFGYTIGNDVSARDLQFRTSQ----WLLGKALPTFAPIGPV 219

Query: 133 IVDKRELD-PSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTP 191
           IV K EL    DL+I  +VNG VRQ G TS+MIF +  +++Y+S    L PGDII TGTP
Sbjct: 220 IVGKNELGFARDLQIITRVNGTVRQNGNTSDMIFDVRAIVDYLSGYFNLGPGDIIFTGTP 279

Query: 192 PGV---------GPLRHGDKIEAWVEGIGVLEEEV 217
            GV           L+HGD I+  + GIG L   +
Sbjct: 280 EGVILGLPENERVWLKHGDVIDVSITGIGTLTNRI 314


>sp|P37352|HPCE_ECOLI HOMOPROTOCATECHUATE CATABOLISM BIFUNCTIONAL ISOMERASE/DECARBOXYLASE
           [INCLUDES: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE
           (HHDD ISOMERASE);
           5-CARBOXYMETHYL-2-OXO-HEX-3-ENE-1,7-DIOATE DECARBOXYLASE
           (OPET DECARBOXYLASE)] >gi|481224|pir||S38348
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase (EC
           5.3.3.10) - Escherichia coli >gi|402576|emb|CAA52936.1|
           (X75028) 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase [Escherichia coli]
           Length = 405
           
 Score =  146 bits (366), Expect = 2e-34
 Identities = 78/178 (43%), Positives = 107/178 (59%), Gaps = 4/178 (2%)

Query: 18  IIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIG 77
           + AL  NYA+HA E+  +PPEEP++FLK P+ L G N   V P   + + +E EL V+IG
Sbjct: 225 LFALGLNYADHASELEFKPPEEPLVFLKAPNTLTGDNQTSVRPNNIEYMHYEAELVVVIG 284

Query: 78  KRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKR 137
           K+A+NV    A DY+ GYT+  D   RD      +   P    K  D   P+   IV K 
Sbjct: 285 KQARNVSEADAMDYVAGYTVCNDYAIRDYLENYYR---PNLRVKSRDGLTPMLSTIVPKE 341

Query: 138 EL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGV 194
            + DP +L +   VNG++RQ G T+++IF +P LI Y+S  MTL PGD+IATGTP G+
Sbjct: 342 AIPDPHNLTLRTFVNGELRQQGTTADLIFSVPFLIAYLSEFMTLNPGDMIATGTPKGL 399


 Score = 80.8 bits (196), Expect = 1e-14
 Identities = 57/188 (30%), Positives = 90/188 (47%), Gaps = 9/188 (4%)

Query: 36  PPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGY 95
           PP+  V F+KP + +IG    I  P+    +     +A+I+GK A  V  E A +YI GY
Sbjct: 31  PPKTAVWFIKPRNTVIGCGEPIPFPQGENLLSGAT-VALIVGKTATKVREEDAAEYIAGY 89

Query: 96  TILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVR 155
            +  D++   L  E+  +  P   +K  D F PIG  +      +  +L I  ++NG+  
Sbjct: 90  ALANDVS---LPEESFYR--PAIKAKCRDGFCPIGETVALS---NVDNLTIYTEINGRPA 141

Query: 156 QLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGPLRHGDKIEAWVEGIGVLEE 215
               TS++     +L+  +S   TL PGD I  GTP     ++ GD++    EG   LE 
Sbjct: 142 DHWNTSDLQRNAAQLLSALSEFATLNPGDAILLGTPQARVEIQPGDRVRVLAEGFPPLEN 201

Query: 216 EVIAEDSI 223
            V+ E  +
Sbjct: 202 PVVDEREV 209


>pir||H72757 hypothetical protein APE0053 - Aeropyrum pernix (strain K1)
           >gi|5103441|dbj|BAA78962.1| (AP000058) 293aa long
           hypothetical protein [Aeropyrum pernix]
           Length = 293
           
 Score =  145 bits (361), Expect = 6e-34
 Identities = 85/215 (39%), Positives = 125/215 (57%), Gaps = 17/215 (7%)

Query: 13  VRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVEL 72
           V P     + ++YAEHAREMG    ++   F KP ++L G  + +V+P  S++ D+E E+
Sbjct: 81  VSPVSAWGVGRSYAEHAREMGMS--KQIAFFSKPVTSLTGHLNPVVVPPVSEKPDYEGEI 138

Query: 73  AVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGP- 131
            +IIGKR KN    +A   I GYT   DIT R LQ         W+++KG DT+ P+GP 
Sbjct: 139 VIIIGKRIKNASTAEAGKAIAGYTAGADITDRLLQDMMS-----WSMAKGLDTYGPVGPV 193

Query: 132 -RIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGT 190
             I+D  + D   L +   +NG+  Q G T +MI  IP+++  +S++ TL PGDI+ TGT
Sbjct: 194 ATIIDSPD-DLDGLCVHTWLNGEKVQRGCTGDMIVSIPDMVSRLSALATLRPGDIVFTGT 252

Query: 191 PPGVGP-------LRHGDKIEAWVEGIGVLEEEVI 218
           PPGVG        LRHGD++E  V G+  L  +++
Sbjct: 253 PPGVGHARKPPRYLRHGDELEVRVSGLPPLRNQIV 287


>dbj|BAA25605.1| (D88014) homologous to HpcE (HHDD isomerase) protein of E. coli
           [Rhodococcus erythropolis]
           Length = 295
           
 Score =  144 bits (360), Expect = 8e-34
 Identities = 78/191 (40%), Positives = 112/191 (57%), Gaps = 4/191 (2%)

Query: 14  RPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELA 73
           RP +I A+  NY +H  E G   PE P +F K P ++ GP + I LP  S  VD EVEL 
Sbjct: 69  RPGQIFAVGVNYRDHVEESGLSLPEAPFVFTKFPGSITGPYNNIELPDGS--VDFEVELV 126

Query: 74  VIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRI 133
            +IG+ A++V A   +DY+ G T+  D++ R LQ         +++ K +  FAPIGP +
Sbjct: 127 AVIGRAARHVDASNGWDYVAGVTLGQDLSERQLQLSGPAP-QQFSLGKSYAGFAPIGPVL 185

Query: 134 VDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPP 192
           V   E  DP D+ +  +++G   Q  RT  +IF IPEL+ Y+SSI+ L PGD+I TGTP 
Sbjct: 186 VTPDEFADPDDIGVSTRLSGDEMQNSRTRHLIFPIPELVAYLSSILPLSPGDLIFTGTPE 245

Query: 193 GVGPLRHGDKI 203
           G+G  R   ++
Sbjct: 246 GIGWTREPKRL 256


>emb|CAA12268.1| (AJ224977) ORF 2 [Sphingomonas sp. RW5]
           Length = 231
           
 Score =  144 bits (360), Expect = 8e-34
 Identities = 74/195 (37%), Positives = 113/195 (57%), Gaps = 1/195 (0%)

Query: 17  KIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSV-IVLPRRSKRVDHEVELAVI 75
           +I  + +NYAEHAREMG +P  EP  F    +  I P+ V +  P  +    +E EL V 
Sbjct: 25  RIFCVGRNYAEHAREMGRDPDREPPFFFTKWAETIVPSDVEVAYPSATANFHYEAELVVA 84

Query: 76  IGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVD 135
           IG   +++P E A D++ GY   LD+T RDLQ +AR +G PW   K  +  +P+G     
Sbjct: 85  IGLEGRDIPVETALDHVFGYATGLDMTRRDLQLKARAEGRPWDTGKNVEQSSPLGLLHPV 144

Query: 136 KRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVG 195
                 S   I L VNG+V+Q    +++I+ + ++I ++S +  L PGD+I TGTP GVG
Sbjct: 145 AECGHLSTGAISLTVNGEVKQSADLADLIWPVADIIAFLSGLYRLLPGDLIYTGTPAGVG 204

Query: 196 PLRHGDKIEAWVEGI 210
           P+  GD+I+  ++G+
Sbjct: 205 PVVPGDEIDVRIDGL 219


>gi|11497711 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-1)
           [Archaeoglobus fulgidus] >gi|7448790|pir||C69261
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-1)
           homolog - Archaeoglobus fulgidus
           >gi|2650557|gb|AAB91138.1| (AE001100)
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-1)
           [Archaeoglobus fulgidus]
           Length = 324
           
 Score =  141 bits (352), Expect = 7e-33
 Identities = 83/218 (38%), Positives = 129/218 (59%), Gaps = 16/218 (7%)

Query: 17  KIIALAKNYAEHAR----EMGSEPPEE----PVIFLKPPSALIGPNSVIVLPRRSKRVDH 68
           K++     + EH R    ++G   P+E    PV +   P ++IGP   ++ P  ++ +D+
Sbjct: 105 KLMVDFSTFEEHVRMGFEKLGMSIPQEWYQVPVGYKMNPYSVIGPEEPVIWPSFTQILDY 164

Query: 69  EVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQ-AEARKKGYPWTVSKGFDTFA 127
           E+E  +++GKR KNV  E A DY+LGYTI+ DI+ARD++  E +        SK FD   
Sbjct: 165 ELEFGIVVGKRGKNVSKEDAMDYVLGYTIVNDISARDMEFIELKAMPLGPLKSKDFDNAT 224

Query: 128 PIGPRIVDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDII 186
           P+GP IV K E+ DP +L++  +VNG+V     T +M +KIP+LI ++S   T+ PG ++
Sbjct: 225 PMGPCIVTKDEIKDPHNLKMVARVNGEVWSEASTKDMHWKIPDLIAHLSKDQTIHPGTVM 284

Query: 187 ATGTPPG-----VGP-LRHGDKIEAWVEGIGVLEEEVI 218
            +GTP G     VG  L+ GD +E  +EGIGVL   ++
Sbjct: 285 LSGTPGGGCGMHVGKLLKPGDVVELEIEGIGVLRNPIV 322


>gb|AAG39451.1| (AF173167) probable maleylpyruvate isomerase [Pseudomonas
           alcaligenes]
           Length = 287
           
 Score =  136 bits (339), Expect = 2e-31
 Identities = 80/215 (37%), Positives = 117/215 (54%), Gaps = 20/215 (9%)

Query: 15  PTKIIALAKNYAEHAREMGSEPP----------EEPVIFLKPPSALIGPNSVIVLPR-RS 63
           P KIIA   NYA+H  E   +            ++  +FLK  S+ +GP+  I LP    
Sbjct: 80  PGKIIAAPVNYADHLDESNQDKGINFGTEISLIDKYALFLKAGSSSVGPDEGISLPAVEG 139

Query: 64  KRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGF 123
           +R DHEVELA++IGK  + V  ++A   + GY I LDIT R  +  + +K         F
Sbjct: 140 RRFDHEVELALVIGKETRRVTVDEALSSVAGYFIGLDITMRGTEDRSYRKS--------F 191

Query: 124 DTFAPIGPRIVDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEP 182
           D+F  +GP +V       P  +   L VNG+ RQ   T+++++ + ++I   S   TL P
Sbjct: 192 DSFTVMGPWLVTSDAFGSPEGVAFSLSVNGEQRQNANTNDLVWSVAKIISVASHAYTLYP 251

Query: 183 GDIIATGTPPGVGPLRHGDKIEAWVEGIGVLEEEV 217
           GD+I TGTP GVGP++ GDKI A ++ IG +E  V
Sbjct: 252 GDVILTGTPAGVGPIKAGDKISASIDRIGSMEVPV 286


>pir||B81094 isomerase, probable NMB1338 [imported] - Neisseria meningitidis
           (group B strain MD58) >gi|7226582|gb|AAF41713.1|
           (AE002482) isomerase, putative [Neisseria meningitidis
           MC58]
           Length = 218
           
 Score =  131 bits (326), Expect = 8e-30
 Identities = 68/194 (35%), Positives = 108/194 (55%), Gaps = 1/194 (0%)

Query: 18  IIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIG 77
           I  + +NYA H  E+ +E P EPV+F+KP  +++     I+LP  S+ V  E EL +++G
Sbjct: 16  IFCIGRNYAAHIEELKNEIPSEPVVFMKPSGSILNSGGTILLPEFSRDVQFECELVLLVG 75

Query: 78  KRAKNVPAEK-AFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDK 136
           K +      K     + GY + LD+TARD+Q   ++KG PW  +KGF   A +       
Sbjct: 76  KDSDGTGEGKDILGCVAGYGVGLDLTARDIQCRLKEKGLPWLKAKGFRHSACVSDFAAAG 135

Query: 137 RELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGP 196
           R  +P  +   LK NG ++Q G T  MI+ I E++  +++   L  GD++ TGTP GVG 
Sbjct: 136 RIGNPEKVLFSLKQNGVLKQRGDTGLMIYPIREILHKLAADYGLGKGDLVFTGTPSGVGA 195

Query: 197 LRHGDKIEAWVEGI 210
           +  GD +   ++G+
Sbjct: 196 IGAGDNLALELDGL 209


>gb|AAF49840.1| (AE003539) CG11251 gene product [Drosophila melanogaster]
           Length = 338
           
 Score =  129 bits (321), Expect = 3e-29
 Identities = 79/215 (36%), Positives = 117/215 (53%), Gaps = 22/215 (10%)

Query: 15  PTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAV 74
           P+KII +  NY ++  E     P EP   +K  S++ G    I     +K +D+  +LAV
Sbjct: 131 PSKIIGVDCNYVDNCDEQHISIPREPSFHVKFASSITGALDNIRAHSSAKHIDYGCQLAV 190

Query: 75  IIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKG---FDTFAPIGP 131
           ++GKR + V  ++A +++ G+ ++ DI ARD           W V  G    DTF P+GP
Sbjct: 191 VMGKRCREVSPKEALNHVFGFMVVQDIVARD-----------WNVPLGGHSMDTFLPLGP 239

Query: 132 RIVDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGT 190
            IV +  + D ++L I   +NG+ RQ G T  MIFKI  LI  +S  +TL PGDII TGT
Sbjct: 240 TIVHRCHVPDLNNLWIKTIINGEERQTGNTRNMIFKIDFLIHRLSQYLTLCPGDIILTGT 299

Query: 191 PPGVGPLRH-------GDKIEAWVEGIGVLEEEVI 218
           P G G  RH       GD IE+ ++ +G +  +V+
Sbjct: 300 PAGSGAFRHPSCFLKPGDLIESEIQNLGKMCNKVV 334


>pir||T50940 DitD protein [imported] - Pseudomonas abietaniphila
           >gi|4455075|gb|AAD21066.1| (AF119621) DitD [Pseudomonas
           abietaniphila]
           Length = 293
           
 Score =  129 bits (320), Expect = 4e-29
 Identities = 75/208 (36%), Positives = 115/208 (55%), Gaps = 11/208 (5%)

Query: 17  KIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVII 76
           ++  +  NY  H + +GS  PE P+ ++KP SAL+G +  I  P  + ++D+EVEL  +I
Sbjct: 69  RVFGVGLNYLSHLQHLGSTAPEHPLGYIKPESALVGASDDIQYPALTAQLDYEVELVAVI 128

Query: 77  GKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIV-- 134
            +   + P   A   +LGYT   DI+ARD  A  R         K  D   P+GP +V  
Sbjct: 129 ARALGDEPCASA--CLLGYTCGNDISARD--AGKRIGRLDLLTQKAMDRTTPVGPWVVTL 184

Query: 135 DKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGV 194
           D+  +    L+I L VN + RQ   T +M+F I EL+ Y+ + +TL+PGD++ TG+  GV
Sbjct: 185 DEIGVGQPHLDIELSVNDECRQFDNTRQMLFPIDELLNYVDARITLQPGDLVFTGSTHGV 244

Query: 195 GP-----LRHGDKIEAWVEGIGVLEEEV 217
           G      L+ GD++E  +EGIG +   V
Sbjct: 245 GLEDGRFLQPGDRVEVRIEGIGSMSNRV 272


>pir||C81847 probable hydrolase NMA1552 [imported] - Neisseria meningitidis
           (group A strain Z2491) >gi|7380193|emb|CAB84779.1|
           (AL162756) putative hydrolase [Neisseria meningitidis
           Z2491]
           Length = 218
           
 Score =  129 bits (320), Expect = 4e-29
 Identities = 67/194 (34%), Positives = 108/194 (55%), Gaps = 1/194 (0%)

Query: 18  IIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIG 77
           I  + +NYA H  E+ +E P EPV+F+KP  +++     I+LP  S+ V  E EL +++G
Sbjct: 16  IFCIGRNYAAHIEELKNEIPSEPVVFMKPSGSILNSGGTILLPEFSRDVQFECELVLLVG 75

Query: 78  KRAKNVPAEK-AFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDK 136
           K +      K     + GY + LD+TARD+Q   ++KG PW  +KGF   A +       
Sbjct: 76  KDSDGTGEGKDILGCVAGYGVGLDLTARDIQCRLKEKGLPWLKAKGFRHSACVSDFAAAG 135

Query: 137 RELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGP 196
           R  +P ++   LK NG ++Q G T  MI+ I E++  +++   L  GD++ TGT  GVG 
Sbjct: 136 RIGNPENVLFSLKQNGVLKQRGDTGLMIYPIREILHKLAADYGLGKGDLVFTGTSSGVGA 195

Query: 197 LRHGDKIEAWVEGI 210
           +  GD +   ++G+
Sbjct: 196 IGAGDNLALELDGL 209


>gb|AAC69614.1| (AF061446) unknown [Chromobacterium violaceum]
           Length = 138
           
 Score =  123 bits (306), Expect = 2e-27
 Identities = 58/115 (50%), Positives = 79/115 (68%)

Query: 9   GYYEVRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDH 68
           G + +R   I  + +NYA HA E+G++  +EP++FLKP SAL+  +S I LP  S  V H
Sbjct: 7   GLHAIRVGNIFCIGRNYAAHAAELGNKVEDEPLVFLKPTSALLDESSPIRLPEYSGDVHH 66

Query: 69  EVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGF 123
           E EL  +IGK   ++P EKA D++ GY I LD+TARD QAEA++KG PWT +KGF
Sbjct: 67  ECELVALIGKGGDDIPPEKALDHVAGYGIGLDLTARDAQAEAKRKGQPWTKAKGF 121


>dbj|BAA36035.1| (D90753) ZK688.3 protein [Escherichia coli]
           Length = 160
           
 Score =  122 bits (304), Expect = 3e-27
 Identities = 64/152 (42%), Positives = 87/152 (57%), Gaps = 1/152 (0%)

Query: 59  LPRRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWT 118
           +P     V HEVELAV+IG   +    E     I GY + LD+T RD+Q + +K G PW 
Sbjct: 1   IPSDFGSVHHEVELAVLIGATLRQATEEHVRKAIAGYGVALDLTLRDVQGKMKKAGQPWE 60

Query: 119 VSKGFDTFAPIGPRIVDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSI 177
            +K FD   P+   I       DP +  + L VNG+ RQ G T++MI KI  LI Y+S  
Sbjct: 61  KAKAFDNSCPLSGFIPAAEFTGDPQNTTLSLSVNGEQRQQGTTADMIHKIVPLIAYMSKF 120

Query: 178 MTLEPGDIIATGTPPGVGPLRHGDKIEAWVEG 209
            TL+ GD++ TGTP GVGPL+ GD++    +G
Sbjct: 121 FTLKAGDVVLTGTPDGVGPLQSGDELTVTFDG 152


>emb|CAA73581.1| (Y13118) ORF1 [Sphingomonas sp.]
           Length = 216
           
 Score =  122 bits (302), Expect = 5e-27
 Identities = 78/217 (35%), Positives = 119/217 (53%), Gaps = 16/217 (7%)

Query: 15  PTKIIALAKNYAEHAR-EMG-SEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVEL 72
           P ++ A+  NY +HA  E G  E P  P+IF K P+ + GP   + LP  +  VD E+EL
Sbjct: 2   PRQVFAVGLNYRDHALGEAGLKELPTSPLIFTKFPTCIAGPYDDLPLPVGN--VDWEIEL 59

Query: 73  AVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYP-WTVSKGFDTFAPIGP 131
             +IG RA  V  E A D++ GY +  D + R +Q      G P +++ K F  F P GP
Sbjct: 60  VAVIGTRASRVSVEDALDHVAGYAVGQDFSERLMQLSG---GMPQFSLGKSFPGFGPFGP 116

Query: 132 RIVDKRELDPSD-LEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGT 190
            +V    LD ++ L +   VNG   Q   TS++IF + +L+  +S + TL PGD+I TGT
Sbjct: 117 WLVTLDALDETNGLAVECTVNGVKVQGSDTSQLIFPVNDLVSRLSHVCTLLPGDVIFTGT 176

Query: 191 PPGVGPLRH-------GDKIEAWVEGIGVLEEEVIAE 220
           P GVG  R+       GD++ + +  IG +++  +A+
Sbjct: 177 PAGVGNARNPKWFLKPGDEVVSTIAQIGSIKQTCVAD 213


>emb|CAA73583.1| (Y13118) ORF2 [Sphingomonas sp.]
           Length = 190
           
 Score =  120 bits (299), Expect = 1e-26
 Identities = 65/173 (37%), Positives = 96/173 (54%), Gaps = 1/173 (0%)

Query: 38  EEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTI 97
           E P  F K  S  +   S I  P  +    +E+EL V IGK+A  +   +A   I G+  
Sbjct: 8   EAPFYFNKAASTFVASGSTIPYPPGTSNYHYEMELVVAIGKQAFQISEAEAGSIIYGFAC 67

Query: 98  LLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVRQL 157
            LD+T RDLQ  AR+KG PW + K F+  A + P I    +    +  I L VNG+++Q 
Sbjct: 68  GLDMTRRDLQLVAREKGRPWDLGKDFEQSAVVAP-ITKAAQFAIENQRISLSVNGEIKQD 126

Query: 158 GRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGPLRHGDKIEAWVEGI 210
              +++++ +PELI  +S    L PGD+I TGTP GVGP+  GD +E  ++G+
Sbjct: 127 QVLADLVWSVPELIADLSRFYHLAPGDLIFTGTPAGVGPVVAGDTLEGTIDGL 179


>pir||F83131 conserved hypothetical protein PA4121 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9950324|gb|AAG07508.1|AE004828_9 (AE004828)
           conserved hypothetical protein [Pseudomonas aeruginosa]
           Length = 219
           
 Score =  117 bits (291), Expect = 1e-25
 Identities = 65/187 (34%), Positives = 109/187 (57%), Gaps = 6/187 (3%)

Query: 35  EPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILG 94
           +PP +PV+F+K P+     ++ ++ PR  +R+     L V+I + A  V  E+A  ++ G
Sbjct: 38  KPPVKPVLFIKTPNTRNEHDAPVLFPRGVERLQPGPALGVVIARDASRVKEEEAMAHVAG 97

Query: 95  YTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKREL-DPSDLEIGLKVNGK 153
           Y I+ + +   L  ++  +  P   +K  D F P+GP++V  +E+ DP  LE+ L VNG+
Sbjct: 98  YVIVNEFS---LPEDSYYR--PAVKAKCRDGFCPLGPQLVPVQEIVDPHALELKLYVNGE 152

Query: 154 VRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGPLRHGDKIEAWVEGIGVL 213
           +RQ   T+ ++  IP LI  IS  MTL  GD++ TGTP G   +  GD++E  ++G+G L
Sbjct: 153 LRQRNNTANLVRDIPRLIAEISEFMTLHAGDVLITGTPEGRVDVHPGDRVEVEIDGLGRL 212

Query: 214 EEEVIAE 220
              ++AE
Sbjct: 213 ANSIVAE 219


>dbj|BAB04790.1| (AP001510) unknown conserved protein in others [Bacillus
           halodurans]
           Length = 206
           
 Score =  115 bits (284), Expect = 6e-25
 Identities = 62/188 (32%), Positives = 103/188 (53%), Gaps = 5/188 (2%)

Query: 18  IIALAKNYAEHAREMGSEPPEEPVIFLKPPSAL-IGPNSVIVLPRRSKRVDHEVELAVII 76
           I  + +NYA+HARE+G+  P++P++F KP  +L I    ++  P     + HE+E+ + I
Sbjct: 6   IYCIGRNYADHARELGNAIPDKPILFSKPTHSLTIANGQMLEFPSNRGEIHHELEIVLHI 65

Query: 77  GKR-AKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVD 135
           GK   K +  E+  D +    + +D T RD Q E +KKG+PW  +KGF   A +      
Sbjct: 66  GKPYEKGISLEELVDVM---ALGIDFTLRDEQNELKKKGHPWLRAKGFKHAAVVTDFWSF 122

Query: 136 KRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVG 195
             E      +  L ++ +V Q G   +M+F   +++E +     L  GD++ TGTP GVG
Sbjct: 123 PGEETCKATDFSLLIHDQVVQKGNIQQMLFSFEQMVEEVGEAFGLGEGDLLFTGTPEGVG 182

Query: 196 PLRHGDKI 203
           P++ GD++
Sbjct: 183 PIQSGDQL 190


>gb|AAD12620.1| (AF036940) fumarylpyruvate hydrolase [Ralstonia sp. U2]
           Length = 192
           
 Score =  114 bits (282), Expect = 1e-24
 Identities = 64/173 (36%), Positives = 93/173 (52%), Gaps = 1/173 (0%)

Query: 38  EEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTI 97
           E+   F K P  L+   + +  P R+    +E+EL + IGK    V  ++A + I GY  
Sbjct: 10  EQAFYFTKSPQTLVESGATVAYPPRTSNYHYEMELVLAIGKPGFRVSEDQAHELIYGYAA 69

Query: 98  LLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVRQL 157
            LD+T RDLQ  AR KG PW   K  +    +   IV  + +      I L+VNG+ +Q 
Sbjct: 70  GLDMTRRDLQLVARDKGRPWDTGKDIEE-GSVCSEIVPMQGVVVEQGAIALEVNGQTKQS 128

Query: 158 GRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGPLRHGDKIEAWVEGI 210
               ++I+ + E+I  +S+   L+PGD+I TGTP GVG +  GDKI   VEGI
Sbjct: 129 SNVDKLIWNVREIIADLSTYYHLQPGDLIYTGTPEGVGAVVAGDKIIGRVEGI 181


>pir||A82389 conserved hypothetical protein VCA1004 [imported] - Vibrio cholerae
           (group O1 strain N16961) >gi|9658447|gb|AAF96900.1|
           (AE004427) conserved hypothetical protein [Vibrio
           cholerae]
           Length = 204
           
 Score =  101 bits (248), Expect = 1e-20
 Identities = 58/186 (31%), Positives = 95/186 (50%), Gaps = 16/186 (8%)

Query: 17  KIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVII 76
           K++ + +NY EH +E+ +  PE+ V+F KP SA+             + + +E E+  ++
Sbjct: 15  KVLCVGRNYVEHIQELHNSIPEQMVLFHKPSSAVTSQLRAF----HQEPLHYEAEICFLV 70

Query: 77  GKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDK 136
            K              +   I LD+T R +Q+  + KG PW  +K FD  A +  R V  
Sbjct: 71  EK-----------GQYVAVGIGLDLTKRQMQSYLKSKGLPWERAKAFDGAAVLS-RFVAL 118

Query: 137 RELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGP 196
             LD  DL + L +N    Q G  S+M++    +++ + S +TLE GD++ TGTP GVG 
Sbjct: 119 DGLDADDLNLELLINSVRVQKGHVSQMLYSPQAVLQELKSYLTLEDGDVVMTGTPQGVGE 178

Query: 197 LRHGDK 202
           +  GD+
Sbjct: 179 VHQGDR 184


>pir||H81417 hypothetical protein Cj0021c [imported] - Campylobacter jejuni
           (strain NCTC 11168) >gi|6967526|emb|CAB72514.1|
           (AL139074) hypothetical protein Cj0021c [Campylobacter
           jejuni]
           Length = 292
           
 Score =  100 bits (247), Expect = 1e-20
 Identities = 74/211 (35%), Positives = 109/211 (51%), Gaps = 19/211 (9%)

Query: 18  IIALAKNYAEHAREMGS------EPPEEPVIFLKPPSALIGPNSVIVLPRR-SKRVDHEV 70
           II L  N+ +HA+E         E  E PV F K  +    P   I L    + ++D+E 
Sbjct: 77  IICLGINFLDHAKESAKFKGEKFEEREYPVYFGKRCNQATAPFGDIPLHADVTSQLDYEC 136

Query: 71  ELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIG 130
           ELA I+ K A  + A+ A DYI GYTI+ +I+AR+LQ    K+   +  +K  +    +G
Sbjct: 137 ELAFILSKDAYKIKAKDAKDYIFGYTIINEISARELQ----KRHKQFYRAKSLEGSTIMG 192

Query: 131 PRIVDKRELD-PSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATG 189
           P I    E+  P  L++   VN ++RQ   T   IF I  ++E +S+ M L+ G II+ G
Sbjct: 193 PYITSVDEISYPPKLQLQSYVNDELRQNSNTQLFIFDIAYVLEELSAGMLLKAGSIISMG 252

Query: 190 TPPGVGP-------LRHGDKIEAWVEGIGVL 213
           TP GVG        L+ GDK+   +E +G L
Sbjct: 253 TPSGVGMGLNPPTFLKSGDKVRCVIENLGEL 283


>pir||T50935 isomerase/decarboxylase homolog DitH [imported] - Pseudomonas
           abietaniphila >gi|4455079|gb|AAD21070.1| (AF119621) DitH
           [Pseudomonas abietaniphila]
           Length = 336
           
 Score = 99.8 bits (245), Expect = 2e-20
 Identities = 64/179 (35%), Positives = 100/179 (55%), Gaps = 7/179 (3%)

Query: 39  EPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTIL 98
           +P+ +     A+IG +   + P  SK +D E+E    IGK+ K++  + A D+I+G+TI 
Sbjct: 140 QPIYYKCNRFAVIGADDEFLWPAFSKALDFELEFGCYIGKKGKDISRDNARDHIVGFTIF 199

Query: 99  LDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKREL-DPSDLEIGLKVNGKVRQL 157
            D++ARD QA           SK FDT   +GP +V   EL DP DL +  +VNG+    
Sbjct: 200 NDMSARDAQAAEMPGMLGPAKSKDFDTANIMGPCLVTADELGDPYDLNMVARVNGEEWGR 259

Query: 158 GRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPP---GVGPLRH---GDKIEAWVEGI 210
           G T +M ++  ++I +IS   TL PG+ + +GT     G+  LR+   GD++E  V+GI
Sbjct: 260 GNTRDMRWRFEDVIAHISRSETLYPGEFLGSGTVGNGCGLEQLRYLKPGDRVELEVDGI 318


>gb|AAK42651.1| 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-1) [Sulfolobus
           solfataricus]
           Length = 318
           
 Score = 98.7 bits (242), Expect = 5e-20
 Identities = 70/200 (35%), Positives = 105/200 (52%), Gaps = 13/200 (6%)

Query: 30  REMGSEPPEE----PVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIGKRAKNVPA 85
           +  G   PEE    P+ +   P+   G    +  P+ SK VD E+E+A II KR K++  
Sbjct: 117 KRRGQPIPEEWFRIPIYYKGDPAIFYGHLEEVPWPKYSKLVDIELEIAAIIYKRGKDIDK 176

Query: 86  EKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKREL-DPSDL 144
            +A DYILG+TI  D +ARD+Q  A  KG     +KG D    +GP IV K EL D   L
Sbjct: 177 IRARDYILGFTIFNDFSARDIQM-AEMKGL-LGPAKGKDFANGLGPWIVTKDELSDIKGL 234

Query: 145 EIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPG-----VG-PLR 198
            +  KVN ++    +  +M +   ++I Y+S    + PGD+  +GT  G     +G  L+
Sbjct: 235 RVYAKVNNEIWCDTKAEDMQWSFEDMIAYVSQDEYIRPGDVFGSGTVSGCTGLDIGKSLK 294

Query: 199 HGDKIEAWVEGIGVLEEEVI 218
               IE +VE IG+L+  ++
Sbjct: 295 PNSSIELYVEKIGILKNIIV 314


>pir||C70585 hypothetical protein Rv0939 - Mycobacterium tuberculosis  (strain
           H37RV) >gi|3261756|emb|CAB08493.1| (Z95209) hypothetical
           protein Rv0939 [Mycobacterium tuberculosis]
           Length = 644
           
 Score = 85.8 bits (209), Expect = 4e-16
 Identities = 65/198 (32%), Positives = 94/198 (46%), Gaps = 23/198 (11%)

Query: 40  PVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTILL 99
           P  +   PS ++GP         S   D E+E+A +IG   K++  E+A   I+GYTI  
Sbjct: 105 PAFYFACPSTVLGPYDDAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFN 164

Query: 100 DITARDLQ-AEARKKGYPWTVSKGFDTFAPIGPRIVDKRELDP------SDLEIGLKVNG 152
           D +ARDLQ  E + +      +KG D+   +GP +V   EL+P        L +   VNG
Sbjct: 165 DWSARDLQMLEGQLR---IGQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNG 221

Query: 153 KVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGV-------------GPLRH 199
            V   G T++M +   E+I Y S  +TL PGD+  +GT P               G L  
Sbjct: 222 TVIGSGSTAQMDWSFGEVIAYASRGVTLTPGDVFGSGTVPTCTLVEHLRPPESFPGWLHD 281

Query: 200 GDKIEAWVEGIGVLEEEV 217
           GD +   VEG+G   + V
Sbjct: 282 GDVVTLQVEGLGETRQTV 299


>gb|AAB58814.1| (U38978) homolog to 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; 
           Method: conceptual translation supplied by author.
           [naphthalenesulfonate-degrading bacterium BN6]
           Length = 144
           
 Score = 81.5 bits (198), Expect = 8e-15
 Identities = 49/147 (33%), Positives = 79/147 (53%), Gaps = 13/147 (8%)

Query: 82  NVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKRELDP 141
           ++  + A  +I+ Y++  D + RD Q +  +    WTV K FD     GP +V   EL  
Sbjct: 1   DISKDDALSHIVAYSVFNDGSIRDYQLKTPQ----WTVGKNFDDTGAFGPWLVTADELPA 56

Query: 142 --SDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVG---- 195
             + L+I  ++NG+V Q   TS+M+F + + +  +S+  TLE GD++  GTP G+G    
Sbjct: 57  GGAGLKIETRLNGQVVQSANTSDMVFDVVDTVALLSTCFTLEAGDVLVMGTPSGIGLARK 116

Query: 196 -PL--RHGDKIEAWVEGIGVLEEEVIA 219
            PL  + GD  E  +E IG+L   + A
Sbjct: 117 PPLFMKDGDVCEVEIEKIGLLVNPIKA 143


>dbj|BAA87171.1| (AB027867) Hypothetical protein [Schizosaccharomyces pombe]
           Length = 114
           
 Score = 80.4 bits (195), Expect = 2e-14
 Identities = 42/107 (39%), Positives = 64/107 (59%), Gaps = 3/107 (2%)

Query: 30  REMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIGKRA---KNVPAE 86
           RE+ +  P +P  FLKP SA++ P    ++        +EVEL +I+  R    + V + 
Sbjct: 1   RELNNPFPTKPFFFLKPTSAIVEPGHGNLIIPPDVSAHYEVELGLIMKDRLPARRPVSSN 60

Query: 87  KAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRI 133
              D I  Y + +D+TAR++Q EA+KKG PW+ +KG+DTF P+GP I
Sbjct: 61  SWLDSIGAYFVGIDMTARNIQNEAKKKGLPWSFAKGYDTFLPVGPII 107


>gb|AAK43045.1| 2-hydroxyhepta-2 ,4-diene-1,7-dioate isomerase (hpcE-3) [Sulfolobus
           solfataricus]
           Length = 288
           
 Score = 79.6 bits (193), Expect = 3e-14
 Identities = 63/199 (31%), Positives = 94/199 (46%), Gaps = 23/199 (11%)

Query: 13  VRPTKIIALAKNYAE----HAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDH 68
           ++P+ II    N  +    + +    E  + P  F+K P+  I     I+ P  + R   
Sbjct: 50  IQPSAIICTLVNSPKMVGVNDKNEAKEMVKSPKFFIKLPTVAIAHRQPIISPPDAIRP-- 107

Query: 69  EVELAVIIGKRAKNVPAEKAFDYILGYTILLDIT-----ARDLQAEARKKGYPWTVSKGF 123
           EVE+ VI   + K+V       YILGYT+  DIT       D     R+      V K  
Sbjct: 108 EVEIGVITRFKMKDVSRSDVKKYILGYTVFNDITYPPGLKEDSYYAMRRDPTDGNVKKLL 167

Query: 124 -----------DTFAPIGPRIVDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELI 171
                      DTFAPIGP IV + E+ D + L +    NG++ Q G +SE IF I E++
Sbjct: 168 MRGTHFRNKVRDTFAPIGPYIVTEEEIGDVNSLRMRSYYNGELVQDGYSSEFIFSIEEIL 227

Query: 172 EYISSIMTLEPGDIIATGT 190
             +S I+T+ P  +I+TG+
Sbjct: 228 SELSKIVTIPPFSVISTGS 246


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.318    0.141    0.412 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91844096
Number of Sequences: 2977
Number of extensions: 4026116
Number of successful extensions: 7907
Number of sequences better than 1.0e-10: 63
Number of HSP's better than  0.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 7735
Number of HSP's gapped (non-prelim): 66
length of query: 225
length of database: 189,106,746
effective HSP length: 53
effective length of query: 172
effective length of database: 157,386,935
effective search space: 27070552820
effective search space used: 27070552820
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 163 (67.9 bits)