BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1451 (hpcE) DE:2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE. (225 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value sp|Q9UYW0|YE51_PYRAB HYPOTHETICAL PROTEIN PAB1451 >gi|7448788|pi... 454 e-127 sp|O58377|Y643_PYRHO HYPOTHETICAL PROTEIN PH0643 >gi|7448782|pir... 425 e-118 sp|Q59050|YG56_METJA HYPOTHETICAL PROTEIN MJ1656 >gi|2127713|pir... 236 1e-61 pir||A69068 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Meth... 218 5e-56 emb|CAB46032.1| (Z97340) isomerase like protein [Arabidopsis tha... 211 7e-54 gi|11499807 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-... 208 3e-53 pir||D70854 hypothetical protein Rv2993c - Mycobacterium tubercu... 206 2e-52 gb|AAK42882.1| 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hp... 203 2e-51 dbj|BAA95083.1| (AB041600) unnamed protein product [Mus musculus] 201 6e-51 dbj|BAB00076.1| (AB022217) isomerase-like protein [Arabidopsis t... 200 1e-50 pir||T29076 hypothetical protein SC1C2.27 - Streptomyces coelico... 199 3e-50 pir||S77124 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxylas... 192 4e-48 pir||T45421 probable 2-hydroxyhepta-2,4-diene-1,7- dioate isomae... 192 4e-48 pir||E75376 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/ 5-car... 189 2e-47 gi|11431155 CGI-105 protein [Homo sapiens] 187 8e-47 dbj|BAB05724.1| (AP001514) 2-hydroxyhepta-2,4-diene-1,7-dioate i... 187 1e-46 gi|7705608 CGI-105 protein [Homo sapiens] >gi|4929679|gb|AAD3410... 186 2e-46 pir||C75575 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/ 5-car... 185 3e-46 pir||C71425 hypothetical protein - Arabidopsis thaliana 183 1e-45 pir||T03559 2-hydroxyhepta-2,4-diene-1, 7-dioateisomerase/ 5-car... 182 3e-45 dbj|BAB05719.1| (AP001514) 2-hydroxyhepta-2,4-diene-1,7-dioate i... 175 3e-43 pir||C69837 5-oxo-1,2,5-tricarboxilic-3-penten acid de homolog y... 173 1e-42 gb|AAG19447.1| (AE005037) 2-hydroxyhepta-2,4-diene-1,7-dioate is... 173 1e-42 emb|CAB65580.1| (AL136058) putative 2-hydroxyhepta-2,4-diene-1,7... 170 1e-41 sp|P34673|YO23_CAEEL HYPOTHETICAL 23.3 KDA PROTEIN ZK688.3 IN CH... 168 4e-41 gb|AAF55854.1| (AE003733) CG5793 gene product [Drosophila melano... 167 9e-41 emb|CAB55708.1| (AL117387) putative 2-hydroxyhepta-2,4-diene-1,7... 166 2e-40 sp|P76004|YCGM_ECOLI PROTEIN YCGM >gi|7448786|pir||A64864 probab... 165 4e-40 sp|Q46978|HPAG_ECOLI 4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTI... 164 1e-39 sp|Q9RPU5|HPAG_SALDU 4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTI... 161 9e-39 emb|CAC12279.1| (AL445066) 2-hydroxyhepta-2, 4-diene-1, 7-dioate... 159 2e-38 gb|AAF55945.1| (AE003737) CG6028 gene product [Drosophila melano... 159 2e-38 pir||G83604 conserved hypothetical protein PA0318 [imported] - P... 159 4e-38 pir||G83131 conserved hypothetical protein PA4122 [imported] - P... 156 2e-37 gi|6324161 Ynl168cp [Saccharomyces cerevisiae] >gi|1730800|sp|P5... 156 2e-37 pir||T50353 homolog to prokaryotic 2-hydroxyhepta-2,4-diene-1,7-... 152 4e-36 pir||A83338 conserved hypothetical protein PA2471 [imported] - P... 152 5e-36 emb|CAC11884.1| (AL445065) probable 2-hydroxyhepta-2, 4-diene-1,... 152 5e-36 sp|P37352|HPCE_ECOLI HOMOPROTOCATECHUATE CATABOLISM BIFUNCTIONAL... 146 2e-34 pir||H72757 hypothetical protein APE0053 - Aeropyrum pernix (str... 145 6e-34 dbj|BAA25605.1| (D88014) homologous to HpcE (HHDD isomerase) pro... 144 8e-34 emb|CAA12268.1| (AJ224977) ORF 2 [Sphingomonas sp. RW5] 144 8e-34 gi|11497711 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-... 141 7e-33 gb|AAG39451.1| (AF173167) probable maleylpyruvate isomerase [Pse... 136 2e-31 pir||B81094 isomerase, probable NMB1338 [imported] - Neisseria m... 131 8e-30 gb|AAF49840.1| (AE003539) CG11251 gene product [Drosophila melan... 129 3e-29 pir||T50940 DitD protein [imported] - Pseudomonas abietaniphila ... 129 4e-29 pir||C81847 probable hydrolase NMA1552 [imported] - Neisseria me... 129 4e-29 gb|AAC69614.1| (AF061446) unknown [Chromobacterium violaceum] 123 2e-27 dbj|BAA36035.1| (D90753) ZK688.3 protein [Escherichia coli] 122 3e-27 emb|CAA73581.1| (Y13118) ORF1 [Sphingomonas sp.] 122 5e-27 emb|CAA73583.1| (Y13118) ORF2 [Sphingomonas sp.] 120 1e-26 pir||F83131 conserved hypothetical protein PA4121 [imported] - P... 117 1e-25 dbj|BAB04790.1| (AP001510) unknown conserved protein in others [... 115 6e-25 gb|AAD12620.1| (AF036940) fumarylpyruvate hydrolase [Ralstonia s... 114 1e-24 pir||A82389 conserved hypothetical protein VCA1004 [imported] - ... 101 1e-20 pir||H81417 hypothetical protein Cj0021c [imported] - Campylobac... 100 1e-20 pir||T50935 isomerase/decarboxylase homolog DitH [imported] - Ps... 100 2e-20 gb|AAK42651.1| 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hp... 99 5e-20 pir||C70585 hypothetical protein Rv0939 - Mycobacterium tubercul... 86 4e-16 gb|AAB58814.1| (U38978) homolog to 2-hydroxyhepta-2,4-diene-1,7-... 82 8e-15 dbj|BAA87171.1| (AB027867) Hypothetical protein [Schizosaccharom... 80 2e-14 gb|AAK43045.1| 2-hydroxyhepta-2 ,4-diene-1,7-dioate isomerase (h... 80 3e-14 >sp|Q9UYW0|YE51_PYRAB HYPOTHETICAL PROTEIN PAB1451 >gi|7448788|pir||A75051 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase. PAB1451 - Pyrococcus abyssi (strain Orsay) >gi|5458815|emb|CAB50302.1| (AJ248287) 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE. [Pyrococcus abyssi] Length = 225 Score = 454 bits (1156), Expect = e-127 Identities = 225/225 (100%), Positives = 225/225 (100%) Query: 1 MIRLPFRDGYYEVRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLP 60 MIRLPFRDGYYEVRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLP Sbjct: 1 MIRLPFRDGYYEVRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLP 60 Query: 61 RRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVS 120 RRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVS Sbjct: 61 RRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVS 120 Query: 121 KGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTL 180 KGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTL Sbjct: 121 KGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTL 180 Query: 181 EPGDIIATGTPPGVGPLRHGDKIEAWVEGIGVLEEEVIAEDSILC 225 EPGDIIATGTPPGVGPLRHGDKIEAWVEGIGVLEEEVIAEDSILC Sbjct: 181 EPGDIIATGTPPGVGPLRHGDKIEAWVEGIGVLEEEVIAEDSILC 225 >sp|O58377|Y643_PYRHO HYPOTHETICAL PROTEIN PH0643 >gi|7448782|pir||D71109 probable 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Pyrococcus horikoshii >gi|3257051|dbj|BAA29734.1| (AP000003) 230aa long hypothetical 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase [Pyrococcus horikoshii] Length = 230 Score = 425 bits (1081), Expect = e-118 Identities = 201/224 (89%), Positives = 217/224 (96%) Query: 2 IRLPFRDGYYEVRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPR 61 +RLPFRDGYY+VRPTKI+ALAKNYAEHAREMGSEPPEEP+IFLKPPSALIGP S I+LPR Sbjct: 7 VRLPFRDGYYDVRPTKIVALAKNYAEHAREMGSEPPEEPIIFLKPPSALIGPGSSIILPR 66 Query: 62 RSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSK 121 RSKRVDHEVELAVI+GKRAKNVPA KAFDYILGYTI+LDITARDLQAEARKKGYPWT+SK Sbjct: 67 RSKRVDHEVELAVIMGKRAKNVPASKAFDYILGYTIILDITARDLQAEARKKGYPWTISK 126 Query: 122 GFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLE 181 GFDTFAPIGPR+VD RELDPSDLEIGLKVNGK+RQLGRTS+MIFKIPELIEYIS IMTLE Sbjct: 127 GFDTFAPIGPRVVDSRELDPSDLEIGLKVNGKIRQLGRTSQMIFKIPELIEYISHIMTLE 186 Query: 182 PGDIIATGTPPGVGPLRHGDKIEAWVEGIGVLEEEVIAEDSILC 225 PGDIIATGTPPGVGPLRHGD+IEAW+EGIG +E +V+AEDSILC Sbjct: 187 PGDIIATGTPPGVGPLRHGDRIEAWIEGIGKMEFDVLAEDSILC 230 >sp|Q59050|YG56_METJA HYPOTHETICAL PROTEIN MJ1656 >gi|2127713|pir||F64506 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase homolog - Methanococcus jannaschii >gi|1500558|gb|AAB99677.1| (U67606) 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE) [Methanococcus jannaschii] Length = 237 Score = 236 bits (597), Expect = 1e-61 Identities = 116/210 (55%), Positives = 155/210 (73%), Gaps = 6/210 (2%) Query: 12 EVRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVE 71 E++PTKII + NY +HA+E+ E PE P+IFLKP SA+I I+ PR SKRVD+EVE Sbjct: 34 EIKPTKIICVGLNYIDHAKELNMEIPEYPIIFLKPTSAIIYNEDYIIRPRISKRVDYEVE 93 Query: 72 LAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGP 131 LA++IGK+ KN+ ++A DYI+GYTIL D+TARDLQ +K WT +K FDTF PIGP Sbjct: 94 LAIVIGKKCKNIKKDEANDYIMGYTILNDVTARDLQ----QKDGQWTRAKSFDTFCPIGP 149 Query: 132 RIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTP 191 RIV +++DP +L I +VNG+++Q T MIF + EL+E+++SIMTL PGDII+TGTP Sbjct: 150 RIV--KDIDPMNLNIECRVNGEIKQKSNTKNMIFDVYELVEFVASIMTLYPGDIISTGTP 207 Query: 192 PGVGPLRHGDKIEAWVEGIGVLEEEVIAED 221 PGVG L+ GD +E +EGIG+L V E+ Sbjct: 208 PGVGELKAGDVVECEIEGIGILRNYVKDEE 237 >pir||A69068 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622625|gb|AAB85982.1| (AE000911) 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase [Methanobacterium thermoautotrophicum] Length = 260 Score = 218 bits (549), Expect = 5e-56 Identities = 105/205 (51%), Positives = 145/205 (70%), Gaps = 6/205 (2%) Query: 13 VRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVEL 72 V P+K++ + NY +HA E+G + P+EP+IFLKPP+ +IG ++ P S VD+EVEL Sbjct: 55 VSPSKVVCVGLNYRDHAAELGMDIPDEPIIFLKPPTTVIGSGDTVIYPEMSSEVDYEVEL 114 Query: 73 AVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPR 132 A ++ +RA+ V + A ++I GYT+L D+TARDLQ R+ G WT +K FDTF PIGP Sbjct: 115 AAVVSERARRVDSSAASEFIAGYTVLNDVTARDLQ---RRDG-QWTRAKSFDTFCPIGP- 169 Query: 133 IVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPP 192 V + ++ P +L+I LK+NG+VRQ TS MIF + EL+E+IS +MTLEPGD+IATGTPP Sbjct: 170 -VIETDVTPDNLDISLKLNGEVRQSSNTSNMIFTVHELLEFISHVMTLEPGDVIATGTPP 228 Query: 193 GVGPLRHGDKIEAWVEGIGVLEEEV 217 GVG + GD + A VEG+G L V Sbjct: 229 GVGQMVPGDTVRATVEGVGTLVNRV 253 >emb|CAB46032.1| (Z97340) isomerase like protein [Arabidopsis thaliana] >gi|7268342|emb|CAB78636.1| (AL161542) isomerase like protein [Arabidopsis thaliana] Length = 222 Score = 211 bits (531), Expect = 7e-54 Identities = 108/217 (49%), Positives = 147/217 (66%), Gaps = 7/217 (3%) Query: 1 MIRLPFRDGYYEVRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLP 60 MI+ F+ G TKI+ + +NYA HA+E+G+ P+EPVIFLKP S+ + I +P Sbjct: 5 MIQRMFKQG------TKIVCVGRNYAAHAKELGNAVPKEPVIFLKPTSSYLENGGTIEIP 58 Query: 61 RRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVS 120 + HEVELA++IG++A++VP A DYI GY + LD+TAR+LQA A+ G PWTV+ Sbjct: 59 HPLDSLHHEVELALVIGQKARDVPESIAMDYIGGYAVALDMTARELQASAKASGLPWTVA 118 Query: 121 KGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTL 180 KG DTF PI + DP +LE+ LKV+G+ RQ G T +MIFK+P LI YISSIMTL Sbjct: 119 KGQDTFTPISSVLPKAMVRDPDNLELWLKVDGETRQKGLTKDMIFKVPYLISYISSIMTL 178 Query: 181 EPGDIIATGTPPGVGPLRHGDKIEAWVEGIGVLEEEV 217 GD+I TGTP GVGP++ G KI A + G+ ++ +V Sbjct: 179 Y-GDVILTGTPEGVGPVKIGQKITAGITGLSEVQFDV 214 >gi|11499807 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-2) [Archaeoglobus fulgidus] >gi|9789822|sp|O28058|YM25_ARCFU HYPOTHETICAL PROTEIN AF2225 >gi|7448784|pir||A69528 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-2) homolog - Archaeoglobus fulgidus >gi|2648302|gb|AAB89031.1| (AE000952) 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-2) [Archaeoglobus fulgidus] Length = 250 Score = 208 bits (525), Expect = 3e-53 Identities = 107/209 (51%), Positives = 143/209 (68%), Gaps = 6/209 (2%) Query: 13 VRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVEL 72 V P+KIIA+ NY +HA E+ PEEP++F+KP +A+IG + I+LP+ S+RVD+E EL Sbjct: 41 VVPSKIIAVGLNYIDHAEELNMPVPEEPILFMKPSTAVIGHDDCIILPQISQRVDYEGEL 100 Query: 73 AVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPR 132 AV+I + +NVP A DYILGYT D+TARDLQA K WT +K FDTFAP+GP Sbjct: 101 AVVIAEDCRNVPETNAADYILGYTCFNDVTARDLQA----KDGQWTRAKSFDTFAPLGPY 156 Query: 133 IVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPP 192 I + DPS L I +VNGKV Q TS +IF + +L+ ++SS+MTL+ GD+IATGTP Sbjct: 157 IAEID--DPSKLGIQTRVNGKVVQKSNTSNLIFDVFQLVSFVSSVMTLKAGDVIATGTPA 214 Query: 193 GVGPLRHGDKIEAWVEGIGVLEEEVIAED 221 GVG L+ GD +E +E IG+L + D Sbjct: 215 GVGMLKDGDVVEVEIEKIGILRNTAVKID 243 >pir||D70854 hypothetical protein Rv2993c - Mycobacterium tuberculosis (strain H37RV) >gi|2791590|emb|CAA16078.1| (AL021287) hypothetical protein Rv2993c [Mycobacterium tuberculosis] Length = 239 Score = 206 bits (519), Expect = 2e-52 Identities = 106/204 (51%), Positives = 138/204 (66%), Gaps = 5/204 (2%) Query: 16 TKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVI 75 +K++ + KNYA+H EMG PP +PVIFLKP +A+IGPN+ I LP + V E ELA++ Sbjct: 35 SKVVCVGKNYADHIAEMGGRPPADPVIFLKPNTAIIGPNTPIRLPANASPVHFEGELAIV 94 Query: 76 IGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIV- 134 IG+ K+VPA +A D ILGYTI D++ARD Q + WT +KG DTF P+GP IV Sbjct: 95 IGRACKDVPAAQAVDNILGYTIGNDVSARDQQ----QSDGQWTRAKGHDTFCPVGPWIVT 150 Query: 135 DKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGV 194 D DP+DLE+ VNG V+Q RTS MI I ++E+IS+IMTL PGD+I TGTP GV Sbjct: 151 DLAPFDPADLELRTVVNGDVKQHARTSLMIHDIGAIVEWISAIMTLLPGDLILTGTPAGV 210 Query: 195 GPLRHGDKIEAWVEGIGVLEEEVI 218 GP+ GD + +EGIG L V+ Sbjct: 211 GPIEDGDTVSITIEGIGTLTNPVV 234 >gb|AAK42882.1| 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-2) [Sulfolobus solfataricus] Length = 304 Score = 203 bits (510), Expect = 2e-51 Identities = 109/214 (50%), Positives = 143/214 (65%), Gaps = 7/214 (3%) Query: 15 PTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAV 74 P KI LA NY H +E +EPP+EP IF K +ALIG N I+ P+ S +VD+E+EL V Sbjct: 91 PEKIFLLAVNYKAHGKETNNEPPKEPYIFTKFSNALIGHNQPILYPKASNKVDYEIELGV 150 Query: 75 IIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKK-GYPWTVSKGFDTFAPIGPRI 133 IIGK+ K V E+AFDY+ GYT+ DI+ RD Q + G W KG DT AP+GP I Sbjct: 151 IIGKQGKYVKRERAFDYVFGYTVFNDISYRDRQFPSEMPYGMRWVHGKGMDTGAPMGPWI 210 Query: 134 VDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPP 192 V K E+ +P +L + L+VNG+VRQ +MIFKI E+IEY+S+ +TL+PGDII+TGTPP Sbjct: 211 VTKDEIPNPYELRLTLRVNGEVRQDAYAEDMIFKIDEIIEYLSNGITLKPGDIISTGTPP 270 Query: 193 GVGP-----LRHGDKIEAWVEGIGVLEEEVIAED 221 GVG L+ GD IEA + IGVL ++ E+ Sbjct: 271 GVGLATGKFLKPGDTIEAEISKIGVLRNYLVKEE 304 >dbj|BAA95083.1| (AB041600) unnamed protein product [Mus musculus] Length = 227 Score = 201 bits (506), Expect = 6e-51 Identities = 91/193 (47%), Positives = 133/193 (68%) Query: 18 IIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIG 77 I+ + +NYA+H +EM S EPV+FLKP +A S +++P + + HEVEL V++G Sbjct: 23 IVCVGRNYADHVKEMRSTVLSEPVLFLKPSTAYAPEGSPVLMPAYCRNLHHEVELGVLLG 82 Query: 78 KRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKR 137 KR + +P A DY+ GY + LD+TARD+Q E +KKG PWT++K F + P+ + ++ Sbjct: 83 KRGEAIPEAAAMDYVAGYALCLDMTARDVQEECKKKGLPWTLAKSFTSSCPVSAFVPKEK 142 Query: 138 ELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGPL 197 DP L + LKVNG++RQ G+TS MIF IP +I Y+S I+TLE GD+I TGTP GVGP+ Sbjct: 143 IPDPHALRLWLKVNGELRQEGKTSSMIFSIPYIISYVSKIITLEEGDLILTGTPKGVGPI 202 Query: 198 RHGDKIEAWVEGI 210 + D+IEA ++G+ Sbjct: 203 KENDEIEAGIDGV 215 >dbj|BAB00076.1| (AB022217) isomerase-like protein [Arabidopsis thaliana] Length = 224 Score = 200 bits (503), Expect = 1e-50 Identities = 100/217 (46%), Positives = 144/217 (66%), Gaps = 6/217 (2%) Query: 1 MIRLPFRDGYYEVRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLP 60 MI+ F+ G TKI+ + NYA HA+E+G+ P++P++FLKP S+ + I +P Sbjct: 5 MIQRLFKQG------TKIVGVGLNYASHAKELGNALPKDPIVFLKPTSSYLENGGTIEIP 58 Query: 61 RRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVS 120 + HEVELAV+IG++A++VP A +YI GY + LD+TAR+LQ A G P T++ Sbjct: 59 HPLDSLHHEVELAVVIGQKARDVPERLAMNYIGGYALALDMTARELQVSAMASGLPCTLA 118 Query: 121 KGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTL 180 KG DTF PI + LDP++LE+ LKV+ + RQ G T +MIFK+P LI YISS+MTL Sbjct: 119 KGQDTFTPISSVLPKAMVLDPNNLELWLKVDDETRQKGWTKDMIFKVPYLISYISSVMTL 178 Query: 181 EPGDIIATGTPPGVGPLRHGDKIEAWVEGIGVLEEEV 217 GD+I TGTP G+GP++ G KI A + G+ ++ +V Sbjct: 179 FKGDVILTGTPEGIGPVKIGQKITAGITGLSEVQFDV 215 >pir||T29076 hypothetical protein SC1C2.27 - Streptomyces coelicolor >gi|3355694|emb|CAA19994.1| (AL031124) hypothetical protein SC1C2.27 [Streptomyces coelicolor A3(2)] Length = 261 Score = 199 bits (500), Expect = 3e-50 Identities = 100/207 (48%), Positives = 135/207 (64%), Gaps = 5/207 (2%) Query: 13 VRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVEL 72 V P+K++A +NYAEHARE+G+E P+ P F KP +++IGP + P ++ + HE EL Sbjct: 56 VLPSKVVAFGRNYAEHARELGNEVPDAPFAFFKPSTSVIGPGDAVQYPSFTEELHHEAEL 115 Query: 73 AVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPR 132 AV+IG+ + VP E+ D I GYT DITARD+Q ++ W +KGFD+ P+GP Sbjct: 116 AVVIGRMCREVPRERVQDVIFGYTCANDITARDVQRREKQ----WARAKGFDSSCPLGPW 171 Query: 133 IVDKRELDPS-DLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTP 191 + +L + DL + L VNG RQLGRTSEMI I +LI IS MTL PGD+I TGTP Sbjct: 172 VETDLDLAAAGDLTVQLTVNGAQRQLGRTSEMIHSIEDLIVNISEAMTLLPGDVILTGTP 231 Query: 192 PGVGPLRHGDKIEAWVEGIGVLEEEVI 218 GVGPL GD++ +EGIG L +V+ Sbjct: 232 AGVGPLNVGDEVAVTIEGIGTLTNKVV 258 >pir||S77124 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxylase/ isomerase - Synechocystis sp. (strain PCC 6803) >gi|1652763|dbj|BAA17682.1| (D90908) 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxilase/isomer [Synechocystis sp.] Length = 276 Score = 192 bits (482), Expect = 4e-48 Identities = 101/206 (49%), Positives = 136/206 (65%), Gaps = 7/206 (3%) Query: 15 PTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAV 74 P+KI+A+ +NY HA E+G++ P EP++F KPPSA+ IV P +S+RVD+E ELAV Sbjct: 57 PSKIVAVGRNYRAHAAELGNDVPAEPLLFFKPPSAIAADQEEIVYPSQSQRVDYEGELAV 116 Query: 75 IIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIV 134 IIGK+ K++ E+A I GYTI DITARDLQ ++ WT +KGFD F P+GP +V Sbjct: 117 IIGKQVKDITEEEAASAIWGYTIANDITARDLQ----RQDSQWTRAKGFDGFCPLGPWVV 172 Query: 135 DKRELDP-SDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPG 193 R +DP + LE + RQ S+M+F P L+ YIS +MTL PGD+I TGTP G Sbjct: 173 --RHIDPEAHLETTVNDEETPRQATAISDMVFTPPVLVSYISRVMTLYPGDVILTGTPEG 230 Query: 194 VGPLRHGDKIEAWVEGIGVLEEEVIA 219 + L+ GDK+E +EGIG L +IA Sbjct: 231 ISALQVGDKVEVEIEGIGNLTNTIIA 256 >pir||T45421 probable 2-hydroxyhepta-2,4-diene-1,7- dioate isomaerase [imported] - Mycobacterium leprae >gi|2414554|emb|CAB16443.1| (Z99263) possible 2-hydroxyhepta-2,4-diene-1,7- dioate isomaerase [Mycobacterium leprae] Length = 242 Score = 192 bits (482), Expect = 4e-48 Identities = 106/207 (51%), Positives = 139/207 (66%), Gaps = 8/207 (3%) Query: 16 TKIIALAKNYAEHAREMGSEP---PEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVEL 72 +K++ + KNYA+H EMG + +PVIFLKP +A+IGPN I LP + V E EL Sbjct: 35 SKVVCIGKNYADHIVEMGGQTGLASADPVIFLKPNTAIIGPNVPIRLPANASPVHFEGEL 94 Query: 73 AVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPR 132 A+++G+ K+VPA +A D ILGYTI D++ARD Q R G WT +KG DTF P+GP Sbjct: 95 ALVVGRSCKDVPAVQAVDCILGYTIGNDMSARDQQ---RADGQ-WTRAKGHDTFCPVGPW 150 Query: 133 IV-DKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTP 191 IV D LDP+DLE+ VNG+V+Q RTS MI I ++E+IS++MTL PGD+I TGTP Sbjct: 151 IVTDLGPLDPADLELRTAVNGEVKQHSRTSLMIHGIGAIMEWISAVMTLLPGDLILTGTP 210 Query: 192 PGVGPLRHGDKIEAWVEGIGVLEEEVI 218 GVGP+ GD + VEGIG L V+ Sbjct: 211 AGVGPVEDGDIVSITVEGIGTLTNPVV 237 >pir||E75376 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/ 5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase-related protein - Deinococcus radiodurans (strain R1) >gi|6459372|gb|AAF11167.1|AE002004_6 (AE002004) 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase-related protein [Deinococcus radiodurans] Length = 250 Score = 189 bits (476), Expect = 2e-47 Identities = 95/203 (46%), Positives = 136/203 (66%), Gaps = 9/203 (4%) Query: 15 PTKIIALAKNYAEHAREMGSEP---PEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVE 71 P+KI+ + +NY +H RE+G++ P EP IFLK P+AL P + P S+ E E Sbjct: 50 PSKIVCVGRNYLDHIRELGNDTGDLPAEPGIFLKGPNALAEPGGTVEYPSWSENFHFEGE 109 Query: 72 LAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGP 131 LA++IG+RA+N+ A++A +LGYT LD+TARD Q K W +K D F P+GP Sbjct: 110 LALVIGQRARNLKADEALGAVLGYTCGLDLTARDRQ----KTDLQWFRAKAADRFCPLGP 165 Query: 132 RIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTP 191 +V + DPSD+ + +VNG+ RQ GRTS MIF + +++ Y++ +TLEPGD++ TGTP Sbjct: 166 WLVT--QFDPSDVRVQTRVNGEPRQDGRTSHMIFDVVQILTYLTRFVTLEPGDVVLTGTP 223 Query: 192 PGVGPLRHGDKIEAWVEGIGVLE 214 GVGPL+ GD++E V+GIGVLE Sbjct: 224 EGVGPLQRGDRVEVEVDGIGVLE 246 >gi|11431155 CGI-105 protein [Homo sapiens] Length = 314 Score = 187 bits (471), Expect = 8e-47 Identities = 91/213 (42%), Positives = 140/213 (65%), Gaps = 10/213 (4%) Query: 14 RPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELA 73 RP K++ + NY +H +E P+EP+IF K S+++GP +VLP +S+ VD EVELA Sbjct: 104 RPDKVVCVGMNYVDHCKEQNVPVPKEPIIFSKFASSIVGPYDEVVLPPQSQEVDWEVELA 163 Query: 74 VIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRI 133 V+IGK+ K++ A A ++ G+T+ D++ARD Q R+ G W + K FDTF P+GP + Sbjct: 164 VVIGKKGKHIKATDAMAHVAGFTVAHDVSARDWQ--MRRNGKQWLLGKTFDTFCPLGPAL 221 Query: 134 VDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPP 192 V K + DP +L+I +VNG+V Q G T++M+FK +LI ++S +T PGD+I TGTPP Sbjct: 222 VTKDSVADPHNLKICCRVNGEVVQSGNTNQMVFKTEDLIAWVSQFVTFYPGDVILTGTPP 281 Query: 193 GVGP-------LRHGDKIEAWVEGIGVLEEEVI 218 GVG L+ GD+++ +E +GV+ +V+ Sbjct: 282 GVGVFRKPPVFLKKGDEVQCEIEELGVIINKVV 314 >dbj|BAB05724.1| (AP001514) 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase [Bacillus halodurans] Length = 276 Score = 187 bits (469), Expect = 1e-46 Identities = 99/209 (47%), Positives = 133/209 (63%), Gaps = 6/209 (2%) Query: 14 RPTKIIALAKNYAEHAREMGSEPPEEPV-IFLKPPSALIGPNSVIVLPRRSKRVDHEVEL 72 RP KI+A NY H +EM + + FLK +++IGPN I+LP ++R+DHE+EL Sbjct: 72 RPGKIVAAPVNYMSHKKEMNVDHTARVLGFFLKATTSIIGPNDPIILPYNNRRIDHELEL 131 Query: 73 AVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPR 132 A +IGKRAK+V E A DYI GYT L D+T R + ++ + K FDTF PIGP Sbjct: 132 AFVIGKRAKHVKKENAHDYIFGYTGLNDVTVRPTKNREEER----CLRKSFDTFTPIGPW 187 Query: 133 IVDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTP 191 IV E+ DP +L I L+VN +VRQ T++M+ I EL+E S +MTLEPGD+IATGTP Sbjct: 188 IVTSDEIKDPQNLTISLQVNHEVRQHVNTNQMVCGIAELVEIFSHVMTLEPGDLIATGTP 247 Query: 192 PGVGPLRHGDKIEAWVEGIGVLEEEVIAE 220 GVGP++ GD + +E IG V+ E Sbjct: 248 DGVGPIKDGDTVTLQMESIGSFSNPVVLE 276 >gi|7705608 CGI-105 protein [Homo sapiens] >gi|4929679|gb|AAD34100.1|AF151863_1 (AF151863) CGI-105 protein [Homo sapiens] Length = 314 Score = 186 bits (468), Expect = 2e-46 Identities = 91/213 (42%), Positives = 140/213 (65%), Gaps = 10/213 (4%) Query: 14 RPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELA 73 RP K++ + NY +H +E P+EP+IF K S+++GP +VLP +S+ VD EVELA Sbjct: 104 RPDKVVCVGMNYVDHCKEQNVPVPKEPIIFSKFASSIVGPYDEVVLPPQSQEVDWEVELA 163 Query: 74 VIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRI 133 V+IGK+ K++ A A ++ G+T+ D++ARD Q R+ G W + K FDTF P+GP + Sbjct: 164 VVIGKKGKHIKATDAMAHVGGFTVAHDVSARDWQ--MRRNGKQWLLGKTFDTFCPLGPAL 221 Query: 134 VDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPP 192 V K + DP +L+I +VNG+V Q G T++M+FK +LI ++S +T PGD+I TGTPP Sbjct: 222 VTKDSVADPHNLKICCRVNGEVVQSGNTNQMVFKTEDLIAWVSQFVTFYPGDVILTGTPP 281 Query: 193 GVGP-------LRHGDKIEAWVEGIGVLEEEVI 218 GVG L+ GD+++ +E +GV+ +V+ Sbjct: 282 GVGVFRKPPVFLKKGDEVQCEIEELGVIINKVV 314 >pir||C75575 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/ 5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase - Deinococcus radiodurans (strain R1) >gi|6460702|gb|AAF12407.1|AE001863_32 (AE001863) 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase [Deinococcus radiodurans] Length = 262 Score = 185 bits (466), Expect = 3e-46 Identities = 96/208 (46%), Positives = 136/208 (65%), Gaps = 4/208 (1%) Query: 15 PTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAV 74 P K+IALA NYA+H E+G + PEEPV+FLKP ++L+ ++ PR +K + +EVEL + Sbjct: 44 PGKVIALALNYADHVAELGFKAPEEPVMFLKPNTSLLPHQGTVIYPRGAKFMHYEVELGI 103 Query: 75 IIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIV 134 +IG+ A+ V A+ A DY+ GYTI D+ RD + + P +KG+DTF P+GP +V Sbjct: 104 VIGRDARRVKAKDADDYVGGYTIANDLVVRDYVSNYYR---PPMRAKGWDTFGPLGPYLV 160 Query: 135 DKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPG 193 E+ DP +L + VNG++RQ G T +MI K PELIE++S MTLE GD+I TGTP G Sbjct: 161 SADEVPDPYNLGLRAYVNGELRQEGSTRDMILKAPELIEFMSRFMTLEAGDVILTGTPKG 220 Query: 194 VGPLRHGDKIEAWVEGIGVLEEEVIAED 221 V + GD + ++G+G LE V ED Sbjct: 221 VSHVHPGDVMRLEIDGLGALENPVALED 248 >pir||C71425 hypothetical protein - Arabidopsis thaliana Length = 367 Score = 183 bits (461), Expect = 1e-45 Identities = 95/188 (50%), Positives = 127/188 (67%), Gaps = 7/188 (3%) Query: 1 MIRLPFRDGYYEVRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLP 60 MI+ F+ G TKI+ + +NYA HA+E+G+ P+EPVIFLKP S+ + I +P Sbjct: 5 MIQRMFKQG------TKIVCVGRNYAAHAKELGNAVPKEPVIFLKPTSSYLENGGTIEIP 58 Query: 61 RRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVS 120 + HEVELA++IG++A++VP A DYI GY + LD+TAR+LQA A+ G PWTV+ Sbjct: 59 HPLDSLHHEVELALVIGQKARDVPESIAMDYIGGYAVALDMTARELQASAKASGLPWTVA 118 Query: 121 KGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTL 180 KG DTF PI + DP +LE+ LKV+G+ RQ G T +MIFK+P LI YISSIMTL Sbjct: 119 KGQDTFTPISSVLPKAMVRDPDNLELWLKVDGETRQKGLTKDMIFKVPYLISYISSIMTL 178 Query: 181 EPGDIIAT 188 GD+I T Sbjct: 179 Y-GDVILT 185 >pir||T03559 2-hydroxyhepta-2,4-diene-1, 7-dioateisomerase/ 5-carboxymethyl-2-oxo-hex-3-ene-1, 7-dioatedecarboxylase - Rhodobacter capsulatus >gi|3128360|gb|AAC16212.1| (AF010496) 2-hydroxyhepta-2,4-diene-1, 7-dioateisomerase/5-carboxymethyl-2-oxo-hex-3-ene-1, 7-dioatedecarboxylase [Rhodobacter capsulatus] Length = 280 Score = 182 bits (457), Expect = 3e-45 Identities = 97/210 (46%), Positives = 129/210 (61%), Gaps = 11/210 (5%) Query: 17 KIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVII 76 K+IA+ NYA+HA E G P EPV+F+K SA+ GP+ + PR S+++D EVELA +I Sbjct: 72 KLIAIGLNYADHAEEAGLTVPPEPVVFMKATSAICGPDDDVEAPRGSEKLDWEVELAFVI 131 Query: 77 GKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDK 136 G RAK V E A D++ GY I D++ R Q E + W K DTFAP+GP +V K Sbjct: 132 GTRAKYVTLEDAMDHVAGYMICNDVSERSFQIE---RSGQWVKGKSHDTFAPLGPWLVTK 188 Query: 137 REL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVG 195 E+ DP L++ L VNG RQ G T+ M++ + L+ Y+S MTLEPGDII TGTPPGVG Sbjct: 189 DEIKDPQALDLWLNVNGVRRQTGTTATMVYGVAFLVHYLSQFMTLEPGDIITTGTPPGVG 248 Query: 196 P-------LRHGDKIEAWVEGIGVLEEEVI 218 L GD IE + G+G + V+ Sbjct: 249 MGSRPPKFLHAGDVIELGITGLGSQRQVVV 278 >dbj|BAB05719.1| (AP001514) 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase [Bacillus halodurans] Length = 319 Score = 175 bits (440), Expect = 3e-43 Identities = 95/209 (45%), Positives = 129/209 (61%), Gaps = 12/209 (5%) Query: 17 KIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVII 76 KII + NY EH EM E P+ PVIF K + +IGP + LP ++++D+E ELA +I Sbjct: 103 KIICVGHNYREHILEMKREIPKYPVIFAKFANTIIGPEDNVPLPSITEQLDYEAELAFVI 162 Query: 77 GKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDK 136 GK+AK+V E A DY+ GYTI+ DITARDLQ ++ W K D P+GP +V K Sbjct: 163 GKKAKDVAKEDALDYVAGYTIVNDITARDLQ----RRTIQWLQGKTLDGSLPMGPWLVTK 218 Query: 137 REL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVG 195 E+ +P LEI L VNG+ RQ T ++F I +L+ ++S IMTLEPGD++ TGTP GVG Sbjct: 219 DEIPNPHQLEITLSVNGEERQRSNTKNLVFSIQDLVVFLSGIMTLEPGDVVCTGTPGGVG 278 Query: 196 P-------LRHGDKIEAWVEGIGVLEEEV 217 L+ GD + +E +G LE V Sbjct: 279 VAREPQLFLQDGDVVRIELEKVGTLENRV 307 >pir||C69837 5-oxo-1,2,5-tricarboxilic-3-penten acid de homolog yisK - Bacillus subtilis >gi|2145376|emb|CAA70682.1| (Y09476) YisK [Bacillus subtilis] >gi|2633411|emb|CAB12915.1| (Z99109) similar to 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxylase [Bacillus subtilis] Length = 301 Score = 173 bits (435), Expect = 1e-42 Identities = 98/216 (45%), Positives = 136/216 (62%), Gaps = 16/216 (7%) Query: 14 RPTK-IIALAKNYAEHAREMGSEP--PEEPVIFLKPPSALIGPNSVIVLPRR-SKRVDHE 69 +P+K II + KNY +HA EMGSE PE P++F K P + G ++ + ++D+E Sbjct: 89 KPSKNIICIGKNYRDHAIEMGSEADIPEHPMVFTKSPVTVTGHGDIVKSHEEVTSQLDYE 148 Query: 70 VELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPI 129 ELAV+IGK + E A+D++ GYTI+ DITARDLQ K+ + + K DT P+ Sbjct: 149 GELAVVIGKSGTRISKEDAYDHVFGYTIVNDITARDLQ----KRHKQFFIGKSLDTTCPM 204 Query: 130 GPRIVDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIAT 188 GP +V K + +P L++ +VNG++RQ G S+MIF IPELIE +S MTLE GDIIAT Sbjct: 205 GPVLVHKSSIQEPERLKVETRVNGELRQSGSASDMIFSIPELIETLSKGMTLEAGDIIAT 264 Query: 189 GTPPGVGP-------LRHGDKIEAWVEGIGVLEEEV 217 GTP GVG LR GDKI+ ++ IG L ++ Sbjct: 265 GTPSGVGKGFTPPKFLRSGDKIDITIDPIGTLSNQI 300 >gb|AAG19447.1| (AE005037) 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; HpcE [Halobacterium sp. NRC-1] Length = 244 Score = 173 bits (435), Expect = 1e-42 Identities = 86/206 (41%), Positives = 128/206 (61%), Gaps = 6/206 (2%) Query: 15 PTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAV 74 P+K++ + +NYA HA E ++ P+ P++FLKPP+A+ G LP + RV+HE ELAV Sbjct: 42 PSKVVCVGRNYAAHADERDADVPDRPLLFLKPPTAVAGHGDATPLPPNT-RVEHEAELAV 100 Query: 75 IIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIV 134 +IG +A+N+ A A + GYT+ D++ R Q + W K FD P+GP + Sbjct: 101 VIGTQARNLDAGAAMAAVEGYTVANDVSNRTDQDREQN----WVRGKAFDGSCPLGPVVA 156 Query: 135 DKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGV 194 E+ P D + L VNG+ RQ G S+ +F +P L+ I++ +TL+PGD++ TGTPPGV Sbjct: 157 TPDEV-PDDATVALDVNGERRQSGSISQFVFDVPTLLAEITAFVTLQPGDVVLTGTPPGV 215 Query: 195 GPLRHGDKIEAWVEGIGVLEEEVIAE 220 G L GD++ A VEG+G LE V+ E Sbjct: 216 GELTDGDRVAASVEGVGTLEHTVVRE 241 >emb|CAB65580.1| (AL136058) putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase. [Streptomyces coelicolor A3(2)] Length = 285 Score = 170 bits (427), Expect = 1e-41 Identities = 89/211 (42%), Positives = 130/211 (61%), Gaps = 13/211 (6%) Query: 17 KIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVII 76 KI+ + NY +HARE G+EPP EPV+F K P ++GP+ +++PR S + D EVELAV+I Sbjct: 75 KIVCIGLNYHDHARETGAEPPAEPVVFFKAPDTVVGPHDTVLVPRGSTKTDWEVELAVVI 134 Query: 77 GKRAKNV-PAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVD 135 G+ A+ + AE+ + GY + D++ R+ Q E +G W K +TF P+GP +V Sbjct: 135 GRTARYLESAEEGLACVAGYAVAHDVSEREFQIE---RGGTWDKGKNCETFNPLGPWLVT 191 Query: 136 KREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGV 194 E+ DP L + L VNG+++Q G T+E IF + E++ Y+S M L PGDII TGTP GV Sbjct: 192 ADEVPDPQRLPLRLWVNGELKQDGTTAEQIFPVGEVVRYLSRFMVLRPGDIINTGTPAGV 251 Query: 195 GP--------LRHGDKIEAWVEGIGVLEEEV 217 LR GD +E +EG+G +E+ Sbjct: 252 AMGQPEPKPYLRAGDVVELEIEGLGRQRQEL 282 >sp|P34673|YO23_CAEEL HYPOTHETICAL 23.3 KDA PROTEIN ZK688.3 IN CHROMOSOME III >gi|630783|pir||S44919 ZK688.3 protein - Caenorhabditis elegans >gi|289782|gb|AAA28230.1| (L16621) coded for by C. elegans cDNAs GenBank:T01366 and T00450; putative [Caenorhabditis elegans] Length = 214 Score = 168 bits (422), Expect = 4e-41 Identities = 84/189 (44%), Positives = 118/189 (61%) Query: 16 TKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVI 75 TKI+ + +NY +HA E+G+ P++P++F+K ++ I IV P + + EVEL V+ Sbjct: 12 TKIVCVGRNYKDHALELGNAIPKKPMLFVKTVNSFIVEGEPIVAPPGCQNLHQEVELGVV 71 Query: 76 IGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVD 135 I K+A + A DYI GYT+ LD+TARD Q EA+K G PW ++K FD PIG + Sbjct: 72 ISKKASRISKSDAMDYIGGYTVALDMTARDFQDEAKKAGAPWFLAKSFDGSCPIGGFLPV 131 Query: 136 KRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVG 195 +P D+E+ K+NGK +Q RT MIF IP L+EY + TLE GD++ TGTP GV Sbjct: 132 SDIPNPHDVELFCKINGKDQQRCRTDVMIFDIPTLLEYTTQFFTLEVGDVVLTGTPAGVT 191 Query: 196 PLRHGDKIE 204 + GD IE Sbjct: 192 KINSGDVIE 200 >gb|AAF55854.1| (AE003733) CG5793 gene product [Drosophila melanogaster] Length = 220 Score = 167 bits (419), Expect = 9e-41 Identities = 85/204 (41%), Positives = 123/204 (59%) Query: 17 KIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVII 76 KI+ +A NY + P+EP++FLKP S+ + IVLP+ +V +EVEL V+I Sbjct: 17 KIVGVALNYMDVVLARNVPVPKEPLVFLKPTSSYLQEGQPIVLPKVFTKVAYEVELGVVI 76 Query: 77 GKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDK 136 GK KNV A Y+ GY + LD+TA+ AR G+PWT+ KGFDT P+ I + Sbjct: 77 GKPCKNVSKADAMSYVAGYCLALDLTAQCNLGPARAAGHPWTLGKGFDTSTPVSQFIPIE 136 Query: 137 RELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGP 196 + DP +L + L VNG ++Q G T+++IFK+P++I Y+S MTLE D+I TGTP G Sbjct: 137 KVTDPHNLPLWLTVNGDLKQNGCTADLIFKVPDIISYVSKYMTLEANDLILTGTPNGADA 196 Query: 197 LRHGDKIEAWVEGIGVLEEEVIAE 220 + GD I+ + + L +V AE Sbjct: 197 FKAGDVIQCGMADLAKLTFQVEAE 220 >emb|CAB55708.1| (AL117387) putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase [Streptomyces coelicolor A3(2)] Length = 292 Score = 166 bits (416), Expect = 2e-40 Identities = 88/206 (42%), Positives = 127/206 (60%), Gaps = 10/206 (4%) Query: 14 RPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELA 73 RP ++ + +NYA HA E GSEPP PVIF KPP+ ++GPN + +PR S R D EVELA Sbjct: 71 RPGAVVCIGQNYAAHAAESGSEPPTRPVIFFKPPNTVVGPNDEVEIPRGSARTDWEVELA 130 Query: 74 VIIGKRAKNVPAE-KAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPR 132 V+IG+ A+ + + +A +++ GY + D++ RD Q E G W+ K TF P+GP Sbjct: 131 VVIGRTARYLDSPGQALEHVAGYAVSNDVSERDFQLE--HSGGQWSKGKSCATFNPLGPF 188 Query: 133 IVDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTP 191 +V E+ D L + VNG+ RQ RT++MIF + +L+ +S + L+PGD+I TGTP Sbjct: 189 LVPADEVPDVQALRLRSFVNGEPRQDSRTADMIFSVAQLVYDLSQYLVLDPGDVINTGTP 248 Query: 192 PGVG------PLRHGDKIEAWVEGIG 211 GV LR GD +E +EG+G Sbjct: 249 EGVALSGRFPYLRPGDVMEIEIEGLG 274 >sp|P76004|YCGM_ECOLI PROTEIN YCGM >gi|7448786|pir||A64864 probable 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase b1180 - Escherichia coli >gi|1787428|gb|AAC74264.1| (AE000216) putative isomerase [Escherichia coli K12] >gi|4062757|dbj|BAA36014.1| (D90751) ZK688.3 protein [Escherichia coli] >gi|4062767|dbj|BAA36027.1| (D90752) ZK688.3 protein [Escherichia coli] Length = 219 Score = 165 bits (414), Expect = 4e-40 Identities = 83/195 (42%), Positives = 117/195 (59%), Gaps = 1/195 (0%) Query: 16 TKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVI 75 +K++ + NYA+H +EMGS PEEPV+F+KP +AL + +P V HEVELAV+ Sbjct: 17 SKVVCVGSNYAKHIKEMGSAVPEEPVLFIKPETALCDLRQPLAIPSDFGSVHHEVELAVL 76 Query: 76 IGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRI-V 134 IG + E I GY + LD+T RD+Q + +K G PW +K FD P+ I Sbjct: 77 IGATLRQATEEHVRKAIAGYGVALDLTLRDVQGKMKKAGQPWEKAKAFDNSCPLSGFIPA 136 Query: 135 DKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGV 194 + DP + + L VNG+ RQ G T++MI KI LI Y+S TL+ GD++ TGTP GV Sbjct: 137 AEFTGDPQNTTLSLSVNGEQRQQGTTADMIHKIVPLIAYMSKFFTLKAGDVVLTGTPDGV 196 Query: 195 GPLRHGDKIEAWVEG 209 GPL+ GD++ +G Sbjct: 197 GPLQSGDELTVTFDG 211 >sp|Q46978|HPAG_ECOLI 4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYLASE [INCLUDES: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE (HHDD ISOMERASE); 5-CARBOXYMETHYL-2-OXO-HEX-3-ENE-1,7-DIOATE DECARBOXYLASE (OPET DECARBOXYLASE)] >gi|757826|emb|CAA86040.1| (Z37980) 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxilase/isomer [Escherichia coli] Length = 429 Score = 164 bits (410), Expect = 1e-39 Identities = 86/206 (41%), Positives = 124/206 (59%), Gaps = 4/206 (1%) Query: 18 IIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIG 77 + AL NYA+HA E+ +PPEEP++FLK P+ L G N V P + + +E EL V+IG Sbjct: 225 LFALGLNYADHASELEFKPPEEPLVFLKAPNTLTGDNQTSVRPNNIEYMHYEAELVVVIG 284 Query: 78 KRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKR 137 K+A+NV A DY+ GYT+ D RD + P K D P+ IV K Sbjct: 285 KQARNVSEADAMDYVAGYTVCNDYAIRDYLENYYR---PNLRVKSRDGLTPMLSTIVPKE 341 Query: 138 EL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGP 196 + DP +L + VNG++RQ G T+++IF +P LI Y+S MTL PGD+IATGTP G+ Sbjct: 342 AIPDPHNLTLRTFVNGELRQQGTTADLIFSVPFLIAYLSEFMTLNPGDMIATGTPKGLSD 401 Query: 197 LRHGDKIEAWVEGIGVLEEEVIAEDS 222 + GD++ VEG+G L +++E++ Sbjct: 402 VVPGDEVVVEVEGVGRLVNRIVSEET 427 Score = 81.5 bits (198), Expect = 8e-15 Identities = 58/188 (30%), Positives = 91/188 (47%), Gaps = 9/188 (4%) Query: 36 PPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGY 95 PP+ V F+KP + +IG I P+ K V +A+I+GK A V E A +YI GY Sbjct: 31 PPKTAVWFIKPRNTVIGCGEPIPFPQGEK-VLSGATVALIVGKTATKVREEDAAEYIAGY 89 Query: 96 TILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVR 155 + D++ L E+ + P +K D F PIG + + +L I ++NG+ Sbjct: 90 ALANDVS---LPEESFYR--PAIKAKCRDGFCPIGETVALS---NVDNLTIYTEINGRPA 141 Query: 156 QLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGPLRHGDKIEAWVEGIGVLEE 215 T+++ +L+ +S TL PGD I GTP ++ GD++ EG LE Sbjct: 142 DHWNTADLQRNAAQLLSALSEFATLNPGDAILLGTPQARVEIQPGDRVRVLAEGFPPLEN 201 Query: 216 EVIAEDSI 223 V+ E + Sbjct: 202 PVVDEREV 209 >sp|Q9RPU5|HPAG_SALDU 4-HYDROXYPHENYLACETATE DEGRADATION BIFUNCTIONAL ISOMERASE/DECARBOXYLASE [INCLUDES: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE (HHDD ISOMERASE); 5-CARBOXYMETHYL-2-OXO-HEX-3-ENE-1,7-DIOATE DECARBOXYLASE (OPET DECARBOXYLASE)] >gi|5833401|gb|AAD53501.1|AF144422_8 (AF144422) HpaG [Salmonella dublin] Length = 429 Score = 161 bits (402), Expect = 9e-39 Identities = 83/206 (40%), Positives = 124/206 (59%), Gaps = 4/206 (1%) Query: 18 IIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIG 77 + AL NYA+HA E+ PP+EP++F+K P+ + V P + + +E EL V+IG Sbjct: 225 LFALGLNYADHASELAFTPPKEPLVFIKAPNTFTEHHQTSVRPNNVEYMHYEAELVVVIG 284 Query: 78 KRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKR 137 K A+ V +A +Y+ GYT+ D RD + P K D PIGP IVDK Sbjct: 285 KTARKVSEAEAMEYVAGYTVCNDYAIRDYLENYYR---PNLRVKSRDGLTPIGPWIVDKE 341 Query: 138 EL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGP 196 + DP +L + VNG++RQ G T+++IF IP LI Y+S MTL+PGD+IATGTP G+ Sbjct: 342 AVSDPHNLTLRTFVNGELRQEGTTADLIFSIPFLISYLSEFMTLQPGDMIATGTPKGLSD 401 Query: 197 LRHGDKIEAWVEGIGVLEEEVIAEDS 222 + GD++ ++G+G L +++ E+S Sbjct: 402 VVPGDEVVLEIKGVGRLVNQIVCEES 427 Score = 81.5 bits (198), Expect = 8e-15 Identities = 58/186 (31%), Positives = 92/186 (49%), Gaps = 9/186 (4%) Query: 36 PPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGY 95 PP+ V F+KP + +I I+ P+ K V +A+I+GK A +E A +YI GY Sbjct: 31 PPKTAVWFIKPRNTVIRHGEPILYPQGEK-VLSGATVALIVGKTASRKRSEAAAEYIAGY 89 Query: 96 TILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVR 155 + +++ L E+ + P +K D F P+G D +L I ++NG+ Sbjct: 90 ALANEVS---LPEESFYR--PAIKAKCRDGFCPLGEMAPLS---DVDNLTIITEINGREA 141 Query: 156 QLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGPLRHGDKIEAWVEGIGVLEE 215 T+++ +L+ +S TL PGD I GTP LR GD++ +G+ LE Sbjct: 142 DHWNTADLQRSAAQLLSALSEFATLNPGDAILLGTPQNRVALRPGDRVRILAKGLPALEN 201 Query: 216 EVIAED 221 V+AED Sbjct: 202 PVVAED 207 >emb|CAC12279.1| (AL445066) 2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase related protein [Thermoplasma acidophilum] Length = 250 Score = 159 bits (399), Expect = 2e-38 Identities = 86/212 (40%), Positives = 124/212 (57%), Gaps = 8/212 (3%) Query: 13 VRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVEL 72 V P KI A N+ H++E ++ P +P F K +AL+G N PR +++D+E E+ Sbjct: 34 VNPGKIFLPAVNFRSHSQESDTKFPPKPYFFTKFSNALVGHNGTAHRPREIEKLDYEGEI 93 Query: 73 AVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQ-AEARKKGYPWTVSKGFDTFAPIGP 131 ++IGKR K + E+A +YI G+TI+ D++ARD Q E GY W K FD P+GP Sbjct: 94 GIVIGKRGKRIGVEEAQNYIFGFTIVDDVSARDYQFPEMHPYGYNWVQGKAFDEALPVGP 153 Query: 132 RIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTP 191 IV + E+ L+I +VNG++RQ G T +M+F + +LI +S +TLEPGD+I TGTP Sbjct: 154 YIVTRDEI-RFPLKIETRVNGELRQSGTTEDMVFSVEQLISTVSQTITLEPGDLITTGTP 212 Query: 192 PGVGP------LRHGDKIEAWVEGIGVLEEEV 217 GV L GD + V GIG L + Sbjct: 213 AGVAAFTEAKYLSDGDTVSISVSGIGELVHRI 244 >gb|AAF55945.1| (AE003737) CG6028 gene product [Drosophila melanogaster] Length = 288 Score = 159 bits (399), Expect = 2e-38 Identities = 87/214 (40%), Positives = 126/214 (58%), Gaps = 12/214 (5%) Query: 15 PTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAV 74 P KII + NY +H E P+EP+ F K +AL+GP ++ S ++D EVEL Sbjct: 77 PGKIICIGLNYQDHCDEQNKPTPKEPLFFSKFNNALVGPQDNVIAHAASSKIDWEVELVC 136 Query: 75 IIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIV 134 +IGK A+ VP +A DY+ GY++ DI+ARD Q E + G + + K DTF P+GP +V Sbjct: 137 VIGKVARQVPKSQAMDYVFGYSVAQDISARDWQKE--RNGGQFLMGKSMDTFLPLGPAVV 194 Query: 135 DKRELDPSDLEIGLK--VNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPP 192 K L P + LK VNG +Q G T +IFK+ ++I +S +TL PGDII TGTP Sbjct: 195 HK-SLVPDVYNLNLKTWVNGVEKQNGNTGNLIFKLDDVINRLSQTITLLPGDIIVTGTPK 253 Query: 193 GVGP-------LRHGDKIEAWVEGIGVLEEEVIA 219 GVG L+ GD +++ + G+G L +++A Sbjct: 254 GVGMHRTPPEFLQPGDVVQSEIVGLGKLCNKIVA 287 >pir||G83604 conserved hypothetical protein PA0318 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9946165|gb|AAG03707.1|AE004470_1 (AE004470) conserved hypothetical protein [Pseudomonas aeruginosa] Length = 221 Score = 159 bits (397), Expect = 4e-38 Identities = 78/203 (38%), Positives = 126/203 (61%), Gaps = 1/203 (0%) Query: 17 KIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVII 76 K++ + +NYAEHA+E+ + P EP++F+KP S ++ + + LP+ V +E E+AV+I Sbjct: 19 KLVCVGRNYAEHAKELNNPVPTEPLLFIKPGSCVVPVSGGLSLPQERGSVHYEAEIAVLI 78 Query: 77 GKRAKNVP-AEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVD 135 GK P E+ D I GY LD+T R++QA+ ++KG PW ++K FD + P + Sbjct: 79 GKPLSRKPNREEVLDAISGYAPALDLTLREVQAKLKEKGLPWELAKSFDGAGVLSPFVNA 138 Query: 136 KRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVG 195 + DP+D+ I L +NG+VRQ G + +M+ I LI++I+ +L+ GD++ TGTP GVG Sbjct: 139 DQFPDPTDIGIRLTINGEVRQDGNSRDMLNPIVPLIQHIAGHFSLQAGDVVLTGTPSGVG 198 Query: 196 PLRHGDKIEAWVEGIGVLEEEVI 218 PL GD++ + G E V+ Sbjct: 199 PLNSGDELLLELPGASRFETRVL 221 >pir||G83131 conserved hypothetical protein PA4122 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9950325|gb|AAG07509.1|AE004828_10 (AE004828) conserved hypothetical protein [Pseudomonas aeruginosa] Length = 259 Score = 156 bits (391), Expect = 2e-37 Identities = 87/204 (42%), Positives = 118/204 (57%), Gaps = 4/204 (1%) Query: 18 IIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIG 77 + AL NYA+HA E+ + P EP+ FLK P G V P + +E EL +IG Sbjct: 46 MFALGLNYADHAAELSFKAPSEPLAFLKSPGTYTGHRQVSWRPDNVDYMHYECELVAVIG 105 Query: 78 KRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKR 137 K A+NV E A Y+ GYT+ D RD + P K D P+GP IVD Sbjct: 106 KPARNVRREDALGYLAGYTVCNDYAIRDYLENYYR---PNLRVKNRDATTPVGPWIVDAA 162 Query: 138 EL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGP 196 E+ +P+ L + VNG++RQ G T++MIF IP LIEY SS MTL+PGD+IATGTP G+ Sbjct: 163 EVPEPNRLTLRTWVNGELRQEGSTADMIFDIPYLIEYFSSFMTLQPGDMIATGTPEGLSD 222 Query: 197 LRHGDKIEAWVEGIGVLEEEVIAE 220 + GD++ VEG+G L +++E Sbjct: 223 VVPGDEVVVEVEGVGRLVNRIVSE 246 >gi|6324161 Ynl168cp [Saccharomyces cerevisiae] >gi|1730800|sp|P53889|YNQ8_YEAST HYPOTHETICAL 28.8 KDA PROTEIN IN PSD1-SKO1 INTERGENIC REGION >gi|2131905|pir||S60959 hypothetical protein YNL168c - yeast (Saccharomyces cerevisiae) >gi|1050785|emb|CAA63271.1| (X92517) N1696 [Saccharomyces cerevisiae] >gi|1302142|emb|CAA96055.1| (Z71444) ORF YNL168c [Saccharomyces cerevisiae] Length = 259 Score = 156 bits (390), Expect = 2e-37 Identities = 89/221 (40%), Positives = 133/221 (59%), Gaps = 36/221 (16%) Query: 17 KIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSV-------------------- 56 KII + +NYA H +E+ + P++P FLKP S+++ P S Sbjct: 11 KIICIGRNYAAHIKELNNSTPKQPFFFLKPTSSIVTPLSSSLVKTTRPANSTFNGLNEDG 70 Query: 57 -----IVLPRRSKRVDHEVELAVIIGKRAKNVPA---EKAFDYILGYTILLDITARDLQA 108 I +PR K V HE+ELA+I+ K NV E+ +D I G + LD+TAR++Q Sbjct: 71 TNPGPIFIPRGVK-VHHEIELALIVSKHLSNVTKMKPEEVYDSISGVALALDLTARNVQD 129 Query: 109 EARKKGYPWTVSKGFDTFAPIGPRIVDKRELD--PSDLE----IGLKVNGKVRQLGRTSE 162 EA+KKG PWT+SKGFDTF PI IV + + S+L+ + VNG++RQ G T+ Sbjct: 130 EAKKKGLPWTISKGFDTFMPIS-AIVSREKFSSYKSNLQDIFRVKCSVNGQLRQDGGTNL 188 Query: 163 MIFKIPELIEYISSIMTLEPGDIIATGTPPGVGPLRHGDKI 203 M+ + +++++IS++++LEPGDII TGTP GVG L+ GD++ Sbjct: 189 MLHPLHKILQHISTMISLEPGDIILTGTPAGVGELKPGDRV 229 >pir||T50353 homolog to prokaryotic 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase [imported] - fission yeast (Schizosaccharomyces pombe) >gi|7106074|emb|CAB76045.1| (AL157918) similar to prokaryotic 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase [Schizosaccharomyces pombe] Length = 221 Score = 152 bits (380), Expect = 4e-36 Identities = 82/208 (39%), Positives = 125/208 (59%), Gaps = 5/208 (2%) Query: 14 RPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELA 73 R K++ + +NYA H RE+ + P +P FLKP SA++ P ++ +EVEL Sbjct: 4 RAGKVVCIGRNYAAHIRELNNPFPTKPFFFLKPTSAIVEPGHGNLIIPPDVSAHYEVELG 63 Query: 74 VIIGKRA---KNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIG 130 +I+ R + V + D I Y + +D+TAR++Q EA+KKG PW+ +KG+DTF P+G Sbjct: 64 LIMKDRLPARRPVSSNSWLDSIGAYFVGIDMTARNIQNEAKKKGLPWSFAKGYDTFLPVG 123 Query: 131 PRIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGT 190 P I DP ++ + L +NGKV Q TS M+ KIP++ I+ M+L PGD++ TGT Sbjct: 124 PIIPKHLIPDPHNVILELSLNGKVVQKDSTSLMLNKIPKIFSSITEAMSLNPGDLVLTGT 183 Query: 191 PPGVGPLRHGDKIEAWVEGIGVLEEEVI 218 P GVGP+ GD + A + + E+E+I Sbjct: 184 PKGVGPVVPGDILSARL--LTAQEQEII 209 >pir||A83338 conserved hypothetical protein PA2471 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9948521|gb|AAG05859.1|AE004674_9 (AE004674) conserved hypothetical protein [Pseudomonas aeruginosa] Length = 232 Score = 152 bits (379), Expect = 5e-36 Identities = 75/207 (36%), Positives = 117/207 (56%), Gaps = 5/207 (2%) Query: 17 KIIALAKNYAEHAREMGSEPPEEPVIFL-KPPSALI----GPNSVIVLPRRSKRVDHEVE 71 ++ + +NYA HAREMG +P EP F KP A++ G + P ++ +E+E Sbjct: 26 RVYCVGRNYAAHAREMGFDPEREPPFFFCKPADAVVPVAAGSTLELAYPSQTGNYHYEIE 85 Query: 72 LAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGP 131 L IGK ++P E+A +++ GY + LD+T RDLQ R+ G PW + K FD APIGP Sbjct: 86 LVAAIGKGGCDIPLEQAEEHVWGYAVGLDMTRRDLQMRMREMGRPWEIGKAFDRSAPIGP 145 Query: 132 RIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTP 191 + P I L+V+G+ RQ ++I+ + E + Y+S L PGD++ TGTP Sbjct: 146 LYPASQVGHPRHAAISLQVDGEDRQRSDIDQLIWSVAETVSYLSRFFELRPGDLVFTGTP 205 Query: 192 PGVGPLRHGDKIEAWVEGIGVLEEEVI 218 GVG + G+++ ++G+G L V+ Sbjct: 206 EGVGAVERGERMLGAIDGLGELSVRVV 232 >emb|CAC11884.1| (AL445065) probable 2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase [Thermoplasma acidophilum] Length = 315 Score = 152 bits (379), Expect = 5e-36 Identities = 90/215 (41%), Positives = 122/215 (55%), Gaps = 19/215 (8%) Query: 13 VRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVEL 72 +R KI+ + NY EHA+E + E P IF K ++IG I +P+ +K++D+E EL Sbjct: 109 LRSGKILCIGVNYMEHAKESRQKVMEHPTIFCKFQDSIIGNMDDITVPKDAKQIDYEGEL 168 Query: 73 AVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPR 132 VIIG+ + + I GYTI D++ARDLQ + W + K TFAPIGP Sbjct: 169 VVIIGRSSGTAESS-----IFGYTIGNDVSARDLQFRTSQ----WLLGKALPTFAPIGPV 219 Query: 133 IVDKRELD-PSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTP 191 IV K EL DL+I +VNG VRQ G TS+MIF + +++Y+S L PGDII TGTP Sbjct: 220 IVGKNELGFARDLQIITRVNGTVRQNGNTSDMIFDVRAIVDYLSGYFNLGPGDIIFTGTP 279 Query: 192 PGV---------GPLRHGDKIEAWVEGIGVLEEEV 217 GV L+HGD I+ + GIG L + Sbjct: 280 EGVILGLPENERVWLKHGDVIDVSITGIGTLTNRI 314 >sp|P37352|HPCE_ECOLI HOMOPROTOCATECHUATE CATABOLISM BIFUNCTIONAL ISOMERASE/DECARBOXYLASE [INCLUDES: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE (HHDD ISOMERASE); 5-CARBOXYMETHYL-2-OXO-HEX-3-ENE-1,7-DIOATE DECARBOXYLASE (OPET DECARBOXYLASE)] >gi|481224|pir||S38348 5-carboxymethyl-2-hydroxymuconate Delta-isomerase (EC 5.3.3.10) - Escherichia coli >gi|402576|emb|CAA52936.1| (X75028) 5-carboxymethyl-2-hydroxymuconate delta-isomerase [Escherichia coli] Length = 405 Score = 146 bits (366), Expect = 2e-34 Identities = 78/178 (43%), Positives = 107/178 (59%), Gaps = 4/178 (2%) Query: 18 IIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIG 77 + AL NYA+HA E+ +PPEEP++FLK P+ L G N V P + + +E EL V+IG Sbjct: 225 LFALGLNYADHASELEFKPPEEPLVFLKAPNTLTGDNQTSVRPNNIEYMHYEAELVVVIG 284 Query: 78 KRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKR 137 K+A+NV A DY+ GYT+ D RD + P K D P+ IV K Sbjct: 285 KQARNVSEADAMDYVAGYTVCNDYAIRDYLENYYR---PNLRVKSRDGLTPMLSTIVPKE 341 Query: 138 EL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGV 194 + DP +L + VNG++RQ G T+++IF +P LI Y+S MTL PGD+IATGTP G+ Sbjct: 342 AIPDPHNLTLRTFVNGELRQQGTTADLIFSVPFLIAYLSEFMTLNPGDMIATGTPKGL 399 Score = 80.8 bits (196), Expect = 1e-14 Identities = 57/188 (30%), Positives = 90/188 (47%), Gaps = 9/188 (4%) Query: 36 PPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGY 95 PP+ V F+KP + +IG I P+ + +A+I+GK A V E A +YI GY Sbjct: 31 PPKTAVWFIKPRNTVIGCGEPIPFPQGENLLSGAT-VALIVGKTATKVREEDAAEYIAGY 89 Query: 96 TILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVR 155 + D++ L E+ + P +K D F PIG + + +L I ++NG+ Sbjct: 90 ALANDVS---LPEESFYR--PAIKAKCRDGFCPIGETVALS---NVDNLTIYTEINGRPA 141 Query: 156 QLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGPLRHGDKIEAWVEGIGVLEE 215 TS++ +L+ +S TL PGD I GTP ++ GD++ EG LE Sbjct: 142 DHWNTSDLQRNAAQLLSALSEFATLNPGDAILLGTPQARVEIQPGDRVRVLAEGFPPLEN 201 Query: 216 EVIAEDSI 223 V+ E + Sbjct: 202 PVVDEREV 209 >pir||H72757 hypothetical protein APE0053 - Aeropyrum pernix (strain K1) >gi|5103441|dbj|BAA78962.1| (AP000058) 293aa long hypothetical protein [Aeropyrum pernix] Length = 293 Score = 145 bits (361), Expect = 6e-34 Identities = 85/215 (39%), Positives = 125/215 (57%), Gaps = 17/215 (7%) Query: 13 VRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVEL 72 V P + ++YAEHAREMG ++ F KP ++L G + +V+P S++ D+E E+ Sbjct: 81 VSPVSAWGVGRSYAEHAREMGMS--KQIAFFSKPVTSLTGHLNPVVVPPVSEKPDYEGEI 138 Query: 73 AVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGP- 131 +IIGKR KN +A I GYT DIT R LQ W+++KG DT+ P+GP Sbjct: 139 VIIIGKRIKNASTAEAGKAIAGYTAGADITDRLLQDMMS-----WSMAKGLDTYGPVGPV 193 Query: 132 -RIVDKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGT 190 I+D + D L + +NG+ Q G T +MI IP+++ +S++ TL PGDI+ TGT Sbjct: 194 ATIIDSPD-DLDGLCVHTWLNGEKVQRGCTGDMIVSIPDMVSRLSALATLRPGDIVFTGT 252 Query: 191 PPGVGP-------LRHGDKIEAWVEGIGVLEEEVI 218 PPGVG LRHGD++E V G+ L +++ Sbjct: 253 PPGVGHARKPPRYLRHGDELEVRVSGLPPLRNQIV 287 >dbj|BAA25605.1| (D88014) homologous to HpcE (HHDD isomerase) protein of E. coli [Rhodococcus erythropolis] Length = 295 Score = 144 bits (360), Expect = 8e-34 Identities = 78/191 (40%), Positives = 112/191 (57%), Gaps = 4/191 (2%) Query: 14 RPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELA 73 RP +I A+ NY +H E G PE P +F K P ++ GP + I LP S VD EVEL Sbjct: 69 RPGQIFAVGVNYRDHVEESGLSLPEAPFVFTKFPGSITGPYNNIELPDGS--VDFEVELV 126 Query: 74 VIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRI 133 +IG+ A++V A +DY+ G T+ D++ R LQ +++ K + FAPIGP + Sbjct: 127 AVIGRAARHVDASNGWDYVAGVTLGQDLSERQLQLSGPAP-QQFSLGKSYAGFAPIGPVL 185 Query: 134 VDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPP 192 V E DP D+ + +++G Q RT +IF IPEL+ Y+SSI+ L PGD+I TGTP Sbjct: 186 VTPDEFADPDDIGVSTRLSGDEMQNSRTRHLIFPIPELVAYLSSILPLSPGDLIFTGTPE 245 Query: 193 GVGPLRHGDKI 203 G+G R ++ Sbjct: 246 GIGWTREPKRL 256 >emb|CAA12268.1| (AJ224977) ORF 2 [Sphingomonas sp. RW5] Length = 231 Score = 144 bits (360), Expect = 8e-34 Identities = 74/195 (37%), Positives = 113/195 (57%), Gaps = 1/195 (0%) Query: 17 KIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSV-IVLPRRSKRVDHEVELAVI 75 +I + +NYAEHAREMG +P EP F + I P+ V + P + +E EL V Sbjct: 25 RIFCVGRNYAEHAREMGRDPDREPPFFFTKWAETIVPSDVEVAYPSATANFHYEAELVVA 84 Query: 76 IGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVD 135 IG +++P E A D++ GY LD+T RDLQ +AR +G PW K + +P+G Sbjct: 85 IGLEGRDIPVETALDHVFGYATGLDMTRRDLQLKARAEGRPWDTGKNVEQSSPLGLLHPV 144 Query: 136 KRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVG 195 S I L VNG+V+Q +++I+ + ++I ++S + L PGD+I TGTP GVG Sbjct: 145 AECGHLSTGAISLTVNGEVKQSADLADLIWPVADIIAFLSGLYRLLPGDLIYTGTPAGVG 204 Query: 196 PLRHGDKIEAWVEGI 210 P+ GD+I+ ++G+ Sbjct: 205 PVVPGDEIDVRIDGL 219 >gi|11497711 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-1) [Archaeoglobus fulgidus] >gi|7448790|pir||C69261 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-1) homolog - Archaeoglobus fulgidus >gi|2650557|gb|AAB91138.1| (AE001100) 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-1) [Archaeoglobus fulgidus] Length = 324 Score = 141 bits (352), Expect = 7e-33 Identities = 83/218 (38%), Positives = 129/218 (59%), Gaps = 16/218 (7%) Query: 17 KIIALAKNYAEHAR----EMGSEPPEE----PVIFLKPPSALIGPNSVIVLPRRSKRVDH 68 K++ + EH R ++G P+E PV + P ++IGP ++ P ++ +D+ Sbjct: 105 KLMVDFSTFEEHVRMGFEKLGMSIPQEWYQVPVGYKMNPYSVIGPEEPVIWPSFTQILDY 164 Query: 69 EVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQ-AEARKKGYPWTVSKGFDTFA 127 E+E +++GKR KNV E A DY+LGYTI+ DI+ARD++ E + SK FD Sbjct: 165 ELEFGIVVGKRGKNVSKEDAMDYVLGYTIVNDISARDMEFIELKAMPLGPLKSKDFDNAT 224 Query: 128 PIGPRIVDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDII 186 P+GP IV K E+ DP +L++ +VNG+V T +M +KIP+LI ++S T+ PG ++ Sbjct: 225 PMGPCIVTKDEIKDPHNLKMVARVNGEVWSEASTKDMHWKIPDLIAHLSKDQTIHPGTVM 284 Query: 187 ATGTPPG-----VGP-LRHGDKIEAWVEGIGVLEEEVI 218 +GTP G VG L+ GD +E +EGIGVL ++ Sbjct: 285 LSGTPGGGCGMHVGKLLKPGDVVELEIEGIGVLRNPIV 322 >gb|AAG39451.1| (AF173167) probable maleylpyruvate isomerase [Pseudomonas alcaligenes] Length = 287 Score = 136 bits (339), Expect = 2e-31 Identities = 80/215 (37%), Positives = 117/215 (54%), Gaps = 20/215 (9%) Query: 15 PTKIIALAKNYAEHAREMGSEPP----------EEPVIFLKPPSALIGPNSVIVLPR-RS 63 P KIIA NYA+H E + ++ +FLK S+ +GP+ I LP Sbjct: 80 PGKIIAAPVNYADHLDESNQDKGINFGTEISLIDKYALFLKAGSSSVGPDEGISLPAVEG 139 Query: 64 KRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGF 123 +R DHEVELA++IGK + V ++A + GY I LDIT R + + +K F Sbjct: 140 RRFDHEVELALVIGKETRRVTVDEALSSVAGYFIGLDITMRGTEDRSYRKS--------F 191 Query: 124 DTFAPIGPRIVDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEP 182 D+F +GP +V P + L VNG+ RQ T+++++ + ++I S TL P Sbjct: 192 DSFTVMGPWLVTSDAFGSPEGVAFSLSVNGEQRQNANTNDLVWSVAKIISVASHAYTLYP 251 Query: 183 GDIIATGTPPGVGPLRHGDKIEAWVEGIGVLEEEV 217 GD+I TGTP GVGP++ GDKI A ++ IG +E V Sbjct: 252 GDVILTGTPAGVGPIKAGDKISASIDRIGSMEVPV 286 >pir||B81094 isomerase, probable NMB1338 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7226582|gb|AAF41713.1| (AE002482) isomerase, putative [Neisseria meningitidis MC58] Length = 218 Score = 131 bits (326), Expect = 8e-30 Identities = 68/194 (35%), Positives = 108/194 (55%), Gaps = 1/194 (0%) Query: 18 IIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIG 77 I + +NYA H E+ +E P EPV+F+KP +++ I+LP S+ V E EL +++G Sbjct: 16 IFCIGRNYAAHIEELKNEIPSEPVVFMKPSGSILNSGGTILLPEFSRDVQFECELVLLVG 75 Query: 78 KRAKNVPAEK-AFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDK 136 K + K + GY + LD+TARD+Q ++KG PW +KGF A + Sbjct: 76 KDSDGTGEGKDILGCVAGYGVGLDLTARDIQCRLKEKGLPWLKAKGFRHSACVSDFAAAG 135 Query: 137 RELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGP 196 R +P + LK NG ++Q G T MI+ I E++ +++ L GD++ TGTP GVG Sbjct: 136 RIGNPEKVLFSLKQNGVLKQRGDTGLMIYPIREILHKLAADYGLGKGDLVFTGTPSGVGA 195 Query: 197 LRHGDKIEAWVEGI 210 + GD + ++G+ Sbjct: 196 IGAGDNLALELDGL 209 >gb|AAF49840.1| (AE003539) CG11251 gene product [Drosophila melanogaster] Length = 338 Score = 129 bits (321), Expect = 3e-29 Identities = 79/215 (36%), Positives = 117/215 (53%), Gaps = 22/215 (10%) Query: 15 PTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAV 74 P+KII + NY ++ E P EP +K S++ G I +K +D+ +LAV Sbjct: 131 PSKIIGVDCNYVDNCDEQHISIPREPSFHVKFASSITGALDNIRAHSSAKHIDYGCQLAV 190 Query: 75 IIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKG---FDTFAPIGP 131 ++GKR + V ++A +++ G+ ++ DI ARD W V G DTF P+GP Sbjct: 191 VMGKRCREVSPKEALNHVFGFMVVQDIVARD-----------WNVPLGGHSMDTFLPLGP 239 Query: 132 RIVDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGT 190 IV + + D ++L I +NG+ RQ G T MIFKI LI +S +TL PGDII TGT Sbjct: 240 TIVHRCHVPDLNNLWIKTIINGEERQTGNTRNMIFKIDFLIHRLSQYLTLCPGDIILTGT 299 Query: 191 PPGVGPLRH-------GDKIEAWVEGIGVLEEEVI 218 P G G RH GD IE+ ++ +G + +V+ Sbjct: 300 PAGSGAFRHPSCFLKPGDLIESEIQNLGKMCNKVV 334 >pir||T50940 DitD protein [imported] - Pseudomonas abietaniphila >gi|4455075|gb|AAD21066.1| (AF119621) DitD [Pseudomonas abietaniphila] Length = 293 Score = 129 bits (320), Expect = 4e-29 Identities = 75/208 (36%), Positives = 115/208 (55%), Gaps = 11/208 (5%) Query: 17 KIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVII 76 ++ + NY H + +GS PE P+ ++KP SAL+G + I P + ++D+EVEL +I Sbjct: 69 RVFGVGLNYLSHLQHLGSTAPEHPLGYIKPESALVGASDDIQYPALTAQLDYEVELVAVI 128 Query: 77 GKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIV-- 134 + + P A +LGYT DI+ARD A R K D P+GP +V Sbjct: 129 ARALGDEPCASA--CLLGYTCGNDISARD--AGKRIGRLDLLTQKAMDRTTPVGPWVVTL 184 Query: 135 DKRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGV 194 D+ + L+I L VN + RQ T +M+F I EL+ Y+ + +TL+PGD++ TG+ GV Sbjct: 185 DEIGVGQPHLDIELSVNDECRQFDNTRQMLFPIDELLNYVDARITLQPGDLVFTGSTHGV 244 Query: 195 GP-----LRHGDKIEAWVEGIGVLEEEV 217 G L+ GD++E +EGIG + V Sbjct: 245 GLEDGRFLQPGDRVEVRIEGIGSMSNRV 272 >pir||C81847 probable hydrolase NMA1552 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7380193|emb|CAB84779.1| (AL162756) putative hydrolase [Neisseria meningitidis Z2491] Length = 218 Score = 129 bits (320), Expect = 4e-29 Identities = 67/194 (34%), Positives = 108/194 (55%), Gaps = 1/194 (0%) Query: 18 IIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIG 77 I + +NYA H E+ +E P EPV+F+KP +++ I+LP S+ V E EL +++G Sbjct: 16 IFCIGRNYAAHIEELKNEIPSEPVVFMKPSGSILNSGGTILLPEFSRDVQFECELVLLVG 75 Query: 78 KRAKNVPAEK-AFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDK 136 K + K + GY + LD+TARD+Q ++KG PW +KGF A + Sbjct: 76 KDSDGTGEGKDILGCVAGYGVGLDLTARDIQCRLKEKGLPWLKAKGFRHSACVSDFAAAG 135 Query: 137 RELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGP 196 R +P ++ LK NG ++Q G T MI+ I E++ +++ L GD++ TGT GVG Sbjct: 136 RIGNPENVLFSLKQNGVLKQRGDTGLMIYPIREILHKLAADYGLGKGDLVFTGTSSGVGA 195 Query: 197 LRHGDKIEAWVEGI 210 + GD + ++G+ Sbjct: 196 IGAGDNLALELDGL 209 >gb|AAC69614.1| (AF061446) unknown [Chromobacterium violaceum] Length = 138 Score = 123 bits (306), Expect = 2e-27 Identities = 58/115 (50%), Positives = 79/115 (68%) Query: 9 GYYEVRPTKIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDH 68 G + +R I + +NYA HA E+G++ +EP++FLKP SAL+ +S I LP S V H Sbjct: 7 GLHAIRVGNIFCIGRNYAAHAAELGNKVEDEPLVFLKPTSALLDESSPIRLPEYSGDVHH 66 Query: 69 EVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGF 123 E EL +IGK ++P EKA D++ GY I LD+TARD QAEA++KG PWT +KGF Sbjct: 67 ECELVALIGKGGDDIPPEKALDHVAGYGIGLDLTARDAQAEAKRKGQPWTKAKGF 121 >dbj|BAA36035.1| (D90753) ZK688.3 protein [Escherichia coli] Length = 160 Score = 122 bits (304), Expect = 3e-27 Identities = 64/152 (42%), Positives = 87/152 (57%), Gaps = 1/152 (0%) Query: 59 LPRRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWT 118 +P V HEVELAV+IG + E I GY + LD+T RD+Q + +K G PW Sbjct: 1 IPSDFGSVHHEVELAVLIGATLRQATEEHVRKAIAGYGVALDLTLRDVQGKMKKAGQPWE 60 Query: 119 VSKGFDTFAPIGPRIVDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSI 177 +K FD P+ I DP + + L VNG+ RQ G T++MI KI LI Y+S Sbjct: 61 KAKAFDNSCPLSGFIPAAEFTGDPQNTTLSLSVNGEQRQQGTTADMIHKIVPLIAYMSKF 120 Query: 178 MTLEPGDIIATGTPPGVGPLRHGDKIEAWVEG 209 TL+ GD++ TGTP GVGPL+ GD++ +G Sbjct: 121 FTLKAGDVVLTGTPDGVGPLQSGDELTVTFDG 152 >emb|CAA73581.1| (Y13118) ORF1 [Sphingomonas sp.] Length = 216 Score = 122 bits (302), Expect = 5e-27 Identities = 78/217 (35%), Positives = 119/217 (53%), Gaps = 16/217 (7%) Query: 15 PTKIIALAKNYAEHAR-EMG-SEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVEL 72 P ++ A+ NY +HA E G E P P+IF K P+ + GP + LP + VD E+EL Sbjct: 2 PRQVFAVGLNYRDHALGEAGLKELPTSPLIFTKFPTCIAGPYDDLPLPVGN--VDWEIEL 59 Query: 73 AVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYP-WTVSKGFDTFAPIGP 131 +IG RA V E A D++ GY + D + R +Q G P +++ K F F P GP Sbjct: 60 VAVIGTRASRVSVEDALDHVAGYAVGQDFSERLMQLSG---GMPQFSLGKSFPGFGPFGP 116 Query: 132 RIVDKRELDPSD-LEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGT 190 +V LD ++ L + VNG Q TS++IF + +L+ +S + TL PGD+I TGT Sbjct: 117 WLVTLDALDETNGLAVECTVNGVKVQGSDTSQLIFPVNDLVSRLSHVCTLLPGDVIFTGT 176 Query: 191 PPGVGPLRH-------GDKIEAWVEGIGVLEEEVIAE 220 P GVG R+ GD++ + + IG +++ +A+ Sbjct: 177 PAGVGNARNPKWFLKPGDEVVSTIAQIGSIKQTCVAD 213 >emb|CAA73583.1| (Y13118) ORF2 [Sphingomonas sp.] Length = 190 Score = 120 bits (299), Expect = 1e-26 Identities = 65/173 (37%), Positives = 96/173 (54%), Gaps = 1/173 (0%) Query: 38 EEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTI 97 E P F K S + S I P + +E+EL V IGK+A + +A I G+ Sbjct: 8 EAPFYFNKAASTFVASGSTIPYPPGTSNYHYEMELVVAIGKQAFQISEAEAGSIIYGFAC 67 Query: 98 LLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVRQL 157 LD+T RDLQ AR+KG PW + K F+ A + P I + + I L VNG+++Q Sbjct: 68 GLDMTRRDLQLVAREKGRPWDLGKDFEQSAVVAP-ITKAAQFAIENQRISLSVNGEIKQD 126 Query: 158 GRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGPLRHGDKIEAWVEGI 210 +++++ +PELI +S L PGD+I TGTP GVGP+ GD +E ++G+ Sbjct: 127 QVLADLVWSVPELIADLSRFYHLAPGDLIFTGTPAGVGPVVAGDTLEGTIDGL 179 >pir||F83131 conserved hypothetical protein PA4121 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9950324|gb|AAG07508.1|AE004828_9 (AE004828) conserved hypothetical protein [Pseudomonas aeruginosa] Length = 219 Score = 117 bits (291), Expect = 1e-25 Identities = 65/187 (34%), Positives = 109/187 (57%), Gaps = 6/187 (3%) Query: 35 EPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILG 94 +PP +PV+F+K P+ ++ ++ PR +R+ L V+I + A V E+A ++ G Sbjct: 38 KPPVKPVLFIKTPNTRNEHDAPVLFPRGVERLQPGPALGVVIARDASRVKEEEAMAHVAG 97 Query: 95 YTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKREL-DPSDLEIGLKVNGK 153 Y I+ + + L ++ + P +K D F P+GP++V +E+ DP LE+ L VNG+ Sbjct: 98 YVIVNEFS---LPEDSYYR--PAVKAKCRDGFCPLGPQLVPVQEIVDPHALELKLYVNGE 152 Query: 154 VRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGPLRHGDKIEAWVEGIGVL 213 +RQ T+ ++ IP LI IS MTL GD++ TGTP G + GD++E ++G+G L Sbjct: 153 LRQRNNTANLVRDIPRLIAEISEFMTLHAGDVLITGTPEGRVDVHPGDRVEVEIDGLGRL 212 Query: 214 EEEVIAE 220 ++AE Sbjct: 213 ANSIVAE 219 >dbj|BAB04790.1| (AP001510) unknown conserved protein in others [Bacillus halodurans] Length = 206 Score = 115 bits (284), Expect = 6e-25 Identities = 62/188 (32%), Positives = 103/188 (53%), Gaps = 5/188 (2%) Query: 18 IIALAKNYAEHAREMGSEPPEEPVIFLKPPSAL-IGPNSVIVLPRRSKRVDHEVELAVII 76 I + +NYA+HARE+G+ P++P++F KP +L I ++ P + HE+E+ + I Sbjct: 6 IYCIGRNYADHARELGNAIPDKPILFSKPTHSLTIANGQMLEFPSNRGEIHHELEIVLHI 65 Query: 77 GKR-AKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVD 135 GK K + E+ D + + +D T RD Q E +KKG+PW +KGF A + Sbjct: 66 GKPYEKGISLEELVDVM---ALGIDFTLRDEQNELKKKGHPWLRAKGFKHAAVVTDFWSF 122 Query: 136 KRELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVG 195 E + L ++ +V Q G +M+F +++E + L GD++ TGTP GVG Sbjct: 123 PGEETCKATDFSLLIHDQVVQKGNIQQMLFSFEQMVEEVGEAFGLGEGDLLFTGTPEGVG 182 Query: 196 PLRHGDKI 203 P++ GD++ Sbjct: 183 PIQSGDQL 190 >gb|AAD12620.1| (AF036940) fumarylpyruvate hydrolase [Ralstonia sp. U2] Length = 192 Score = 114 bits (282), Expect = 1e-24 Identities = 64/173 (36%), Positives = 93/173 (52%), Gaps = 1/173 (0%) Query: 38 EEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTI 97 E+ F K P L+ + + P R+ +E+EL + IGK V ++A + I GY Sbjct: 10 EQAFYFTKSPQTLVESGATVAYPPRTSNYHYEMELVLAIGKPGFRVSEDQAHELIYGYAA 69 Query: 98 LLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKRELDPSDLEIGLKVNGKVRQL 157 LD+T RDLQ AR KG PW K + + IV + + I L+VNG+ +Q Sbjct: 70 GLDMTRRDLQLVARDKGRPWDTGKDIEE-GSVCSEIVPMQGVVVEQGAIALEVNGQTKQS 128 Query: 158 GRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGPLRHGDKIEAWVEGI 210 ++I+ + E+I +S+ L+PGD+I TGTP GVG + GDKI VEGI Sbjct: 129 SNVDKLIWNVREIIADLSTYYHLQPGDLIYTGTPEGVGAVVAGDKIIGRVEGI 181 >pir||A82389 conserved hypothetical protein VCA1004 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9658447|gb|AAF96900.1| (AE004427) conserved hypothetical protein [Vibrio cholerae] Length = 204 Score = 101 bits (248), Expect = 1e-20 Identities = 58/186 (31%), Positives = 95/186 (50%), Gaps = 16/186 (8%) Query: 17 KIIALAKNYAEHAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVII 76 K++ + +NY EH +E+ + PE+ V+F KP SA+ + + +E E+ ++ Sbjct: 15 KVLCVGRNYVEHIQELHNSIPEQMVLFHKPSSAVTSQLRAF----HQEPLHYEAEICFLV 70 Query: 77 GKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDK 136 K + I LD+T R +Q+ + KG PW +K FD A + R V Sbjct: 71 EK-----------GQYVAVGIGLDLTKRQMQSYLKSKGLPWERAKAFDGAAVLS-RFVAL 118 Query: 137 RELDPSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVGP 196 LD DL + L +N Q G S+M++ +++ + S +TLE GD++ TGTP GVG Sbjct: 119 DGLDADDLNLELLINSVRVQKGHVSQMLYSPQAVLQELKSYLTLEDGDVVMTGTPQGVGE 178 Query: 197 LRHGDK 202 + GD+ Sbjct: 179 VHQGDR 184 >pir||H81417 hypothetical protein Cj0021c [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6967526|emb|CAB72514.1| (AL139074) hypothetical protein Cj0021c [Campylobacter jejuni] Length = 292 Score = 100 bits (247), Expect = 1e-20 Identities = 74/211 (35%), Positives = 109/211 (51%), Gaps = 19/211 (9%) Query: 18 IIALAKNYAEHAREMGS------EPPEEPVIFLKPPSALIGPNSVIVLPRR-SKRVDHEV 70 II L N+ +HA+E E E PV F K + P I L + ++D+E Sbjct: 77 IICLGINFLDHAKESAKFKGEKFEEREYPVYFGKRCNQATAPFGDIPLHADVTSQLDYEC 136 Query: 71 ELAVIIGKRAKNVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIG 130 ELA I+ K A + A+ A DYI GYTI+ +I+AR+LQ K+ + +K + +G Sbjct: 137 ELAFILSKDAYKIKAKDAKDYIFGYTIINEISARELQ----KRHKQFYRAKSLEGSTIMG 192 Query: 131 PRIVDKRELD-PSDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATG 189 P I E+ P L++ VN ++RQ T IF I ++E +S+ M L+ G II+ G Sbjct: 193 PYITSVDEISYPPKLQLQSYVNDELRQNSNTQLFIFDIAYVLEELSAGMLLKAGSIISMG 252 Query: 190 TPPGVGP-------LRHGDKIEAWVEGIGVL 213 TP GVG L+ GDK+ +E +G L Sbjct: 253 TPSGVGMGLNPPTFLKSGDKVRCVIENLGEL 283 >pir||T50935 isomerase/decarboxylase homolog DitH [imported] - Pseudomonas abietaniphila >gi|4455079|gb|AAD21070.1| (AF119621) DitH [Pseudomonas abietaniphila] Length = 336 Score = 99.8 bits (245), Expect = 2e-20 Identities = 64/179 (35%), Positives = 100/179 (55%), Gaps = 7/179 (3%) Query: 39 EPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTIL 98 +P+ + A+IG + + P SK +D E+E IGK+ K++ + A D+I+G+TI Sbjct: 140 QPIYYKCNRFAVIGADDEFLWPAFSKALDFELEFGCYIGKKGKDISRDNARDHIVGFTIF 199 Query: 99 LDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKREL-DPSDLEIGLKVNGKVRQL 157 D++ARD QA SK FDT +GP +V EL DP DL + +VNG+ Sbjct: 200 NDMSARDAQAAEMPGMLGPAKSKDFDTANIMGPCLVTADELGDPYDLNMVARVNGEEWGR 259 Query: 158 GRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPP---GVGPLRH---GDKIEAWVEGI 210 G T +M ++ ++I +IS TL PG+ + +GT G+ LR+ GD++E V+GI Sbjct: 260 GNTRDMRWRFEDVIAHISRSETLYPGEFLGSGTVGNGCGLEQLRYLKPGDRVELEVDGI 318 >gb|AAK42651.1| 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-1) [Sulfolobus solfataricus] Length = 318 Score = 98.7 bits (242), Expect = 5e-20 Identities = 70/200 (35%), Positives = 105/200 (52%), Gaps = 13/200 (6%) Query: 30 REMGSEPPEE----PVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIGKRAKNVPA 85 + G PEE P+ + P+ G + P+ SK VD E+E+A II KR K++ Sbjct: 117 KRRGQPIPEEWFRIPIYYKGDPAIFYGHLEEVPWPKYSKLVDIELEIAAIIYKRGKDIDK 176 Query: 86 EKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKREL-DPSDL 144 +A DYILG+TI D +ARD+Q A KG +KG D +GP IV K EL D L Sbjct: 177 IRARDYILGFTIFNDFSARDIQM-AEMKGL-LGPAKGKDFANGLGPWIVTKDELSDIKGL 234 Query: 145 EIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPG-----VG-PLR 198 + KVN ++ + +M + ++I Y+S + PGD+ +GT G +G L+ Sbjct: 235 RVYAKVNNEIWCDTKAEDMQWSFEDMIAYVSQDEYIRPGDVFGSGTVSGCTGLDIGKSLK 294 Query: 199 HGDKIEAWVEGIGVLEEEVI 218 IE +VE IG+L+ ++ Sbjct: 295 PNSSIELYVEKIGILKNIIV 314 >pir||C70585 hypothetical protein Rv0939 - Mycobacterium tuberculosis (strain H37RV) >gi|3261756|emb|CAB08493.1| (Z95209) hypothetical protein Rv0939 [Mycobacterium tuberculosis] Length = 644 Score = 85.8 bits (209), Expect = 4e-16 Identities = 65/198 (32%), Positives = 94/198 (46%), Gaps = 23/198 (11%) Query: 40 PVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIGKRAKNVPAEKAFDYILGYTILL 99 P + PS ++GP S D E+E+A +IG K++ E+A I+GYTI Sbjct: 105 PAFYFACPSTVLGPYDDAPTAPGSAWQDFELEIAAVIGTSGKDLTVEQAERSIIGYTIFN 164 Query: 100 DITARDLQ-AEARKKGYPWTVSKGFDTFAPIGPRIVDKRELDP------SDLEIGLKVNG 152 D +ARDLQ E + + +KG D+ +GP +V EL+P L + VNG Sbjct: 165 DWSARDLQMLEGQLR---IGQAKGKDSGITLGPYLVTPDELEPYCRGGKLSLRVIALVNG 221 Query: 153 KVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGV-------------GPLRH 199 V G T++M + E+I Y S +TL PGD+ +GT P G L Sbjct: 222 TVIGSGSTAQMDWSFGEVIAYASRGVTLTPGDVFGSGTVPTCTLVEHLRPPESFPGWLHD 281 Query: 200 GDKIEAWVEGIGVLEEEV 217 GD + VEG+G + V Sbjct: 282 GDVVTLQVEGLGETRQTV 299 >gb|AAB58814.1| (U38978) homolog to 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Method: conceptual translation supplied by author. [naphthalenesulfonate-degrading bacterium BN6] Length = 144 Score = 81.5 bits (198), Expect = 8e-15 Identities = 49/147 (33%), Positives = 79/147 (53%), Gaps = 13/147 (8%) Query: 82 NVPAEKAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRIVDKRELDP 141 ++ + A +I+ Y++ D + RD Q + + WTV K FD GP +V EL Sbjct: 1 DISKDDALSHIVAYSVFNDGSIRDYQLKTPQ----WTVGKNFDDTGAFGPWLVTADELPA 56 Query: 142 --SDLEIGLKVNGKVRQLGRTSEMIFKIPELIEYISSIMTLEPGDIIATGTPPGVG---- 195 + L+I ++NG+V Q TS+M+F + + + +S+ TLE GD++ GTP G+G Sbjct: 57 GGAGLKIETRLNGQVVQSANTSDMVFDVVDTVALLSTCFTLEAGDVLVMGTPSGIGLARK 116 Query: 196 -PL--RHGDKIEAWVEGIGVLEEEVIA 219 PL + GD E +E IG+L + A Sbjct: 117 PPLFMKDGDVCEVEIEKIGLLVNPIKA 143 >dbj|BAA87171.1| (AB027867) Hypothetical protein [Schizosaccharomyces pombe] Length = 114 Score = 80.4 bits (195), Expect = 2e-14 Identities = 42/107 (39%), Positives = 64/107 (59%), Gaps = 3/107 (2%) Query: 30 REMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDHEVELAVIIGKRA---KNVPAE 86 RE+ + P +P FLKP SA++ P ++ +EVEL +I+ R + V + Sbjct: 1 RELNNPFPTKPFFFLKPTSAIVEPGHGNLIIPPDVSAHYEVELGLIMKDRLPARRPVSSN 60 Query: 87 KAFDYILGYTILLDITARDLQAEARKKGYPWTVSKGFDTFAPIGPRI 133 D I Y + +D+TAR++Q EA+KKG PW+ +KG+DTF P+GP I Sbjct: 61 SWLDSIGAYFVGIDMTARNIQNEAKKKGLPWSFAKGYDTFLPVGPII 107 >gb|AAK43045.1| 2-hydroxyhepta-2 ,4-diene-1,7-dioate isomerase (hpcE-3) [Sulfolobus solfataricus] Length = 288 Score = 79.6 bits (193), Expect = 3e-14 Identities = 63/199 (31%), Positives = 94/199 (46%), Gaps = 23/199 (11%) Query: 13 VRPTKIIALAKNYAE----HAREMGSEPPEEPVIFLKPPSALIGPNSVIVLPRRSKRVDH 68 ++P+ II N + + + E + P F+K P+ I I+ P + R Sbjct: 50 IQPSAIICTLVNSPKMVGVNDKNEAKEMVKSPKFFIKLPTVAIAHRQPIISPPDAIRP-- 107 Query: 69 EVELAVIIGKRAKNVPAEKAFDYILGYTILLDIT-----ARDLQAEARKKGYPWTVSKGF 123 EVE+ VI + K+V YILGYT+ DIT D R+ V K Sbjct: 108 EVEIGVITRFKMKDVSRSDVKKYILGYTVFNDITYPPGLKEDSYYAMRRDPTDGNVKKLL 167 Query: 124 -----------DTFAPIGPRIVDKREL-DPSDLEIGLKVNGKVRQLGRTSEMIFKIPELI 171 DTFAPIGP IV + E+ D + L + NG++ Q G +SE IF I E++ Sbjct: 168 MRGTHFRNKVRDTFAPIGPYIVTEEEIGDVNSLRMRSYYNGELVQDGYSSEFIFSIEEIL 227 Query: 172 EYISSIMTLEPGDIIATGT 190 +S I+T+ P +I+TG+ Sbjct: 228 SELSKIVTIPPFSVISTGS 246 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.318 0.141 0.412 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 91844096 Number of Sequences: 2977 Number of extensions: 4026116 Number of successful extensions: 7907 Number of sequences better than 1.0e-10: 63 Number of HSP's better than 0.0 without gapping: 46 Number of HSP's successfully gapped in prelim test: 17 Number of HSP's that attempted gapping in prelim test: 7735 Number of HSP's gapped (non-prelim): 66 length of query: 225 length of database: 189,106,746 effective HSP length: 53 effective length of query: 172 effective length of database: 157,386,935 effective search space: 27070552820 effective search space used: 27070552820 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.7 bits) S2: 163 (67.9 bits)