BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1465 (pol30) DE:proliferating-cell nuclear antigen (pol30)
(249 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||G75048 proliferating-cell nuclear antigen (pol30) PAB1465 -... 482 e-135
sp|O58398|PCNA_PYRHO PROLIFERATING CELL NUCLEAR ANTIGEN HOMOLOG ... 460 e-129
dbj|BAA33020.2| (AB017486) Proliferation cell nuclear antigen [P... 447 e-125
sp|O73947|PCNA_PYRFU PROLIFERATING CELL NUCLEAR ANTIGEN HOMOLOG ... 445 e-124
emb|CAB59006.1| (AJ130939) proliferating cell nuclear antigen (P... 429 e-119
sp|Q57697|PCNA_METJA PROLIFERATING CELL NUCLEAR ANTIGEN HOMOLOG ... 201 6e-51
pir||G72771 probable Proliferating call nuclear antigen homolog ... 151 8e-36
gb|AAK40734.1| Proliferating cell nuclear antigen homolog (PCNA)... 151 8e-36
pir||E72738 probable proliferating cell nuclear antigen APE0441 ... 141 9e-33
gb|AAK41309.1| Proliferating cell nuclear antigen homolog (PCNA)... 129 2e-29
sp|O27367|PCNA_METTH PROLIFERATING CELL NUCLEAR ANTIGEN HOMOLOG ... 129 4e-29
emb|CAB93143.1| (AJ278286) proliferating cell nuclear antigen [H... 127 9e-29
gb|AAG20376.1| (AE005110) proliferating-cell nuclear antigen; Pc... 118 5e-26
pir||A72526 hypothetical protein APE2182 - Aeropyrum pernix (str... 116 3e-25
emb|CAC12046.1| (AL445065) proliferating cell nuclear antigen (P... 111 1e-23
gi|11497947 proliferating-cell nuclear antigen (pol30) [Archaeog... 108 5e-23
dbj|BAA92700.1| (AB039962) proliferating cell nuclear antigen su... 103 2e-21
pir||I48707 proliferating cell nuclear antigen - mouse >gi|53600... 101 7e-21
gi|9627791 proliferating cell nuclear antigen [Autographa califo... 101 1e-20
gb|AAK40726.1| Proliferating cell nuclear antigen putative homol... 100 3e-20
gi|7242171 proliferating cell nuclear antigen [Mus musculus] >gi... 100 3e-20
gi|4505641 proliferating cell nuclear antigen [Homo sapiens] >gi... 100 3e-20
sp|P18248|PCNA_XENLA PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (... 100 3e-20
pdb|1AXC|E Chain E, Human Pcna >gi|2914385|pdb|1AXC|C Chain C, H... 100 3e-20
dbj|BAA77390.1| (AB025357) proliferating cell nuclear antigen [A... 99 3e-20
gb|AAG10077.1|AF294427_1 (AF294427) proliferating cell nuclear a... 99 3e-20
sp|P04961|PCNA_RAT PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (CY... 99 4e-20
sp|P53358|PCNA_STYCL PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (... 98 7e-20
sp|O02115|PCNA_CAEEL PROBABLE PROLIFERATING CELL NUCLEAR ANTIGEN... 98 1e-19
gb|AAF53835.1| (AE003663) CG10262 gene product [Drosophila melan... 98 1e-19
sp|Q03392|PCNA_SCHPO PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) >... 96 3e-19
gb|AAB31034.1| proliferating cell nuclear antigen, PCNA [Sacchar... 96 5e-19
emb|CAC17700.1| (AJ301669) putative proliferating cell nuclear a... 95 6e-19
gi|9632127 similar to Periwinkle PCNA, corresponds to GenBank Ac... 95 8e-19
sp|P24314|PCNA_CATRO PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (... 94 1e-18
sp|Q00265|PCN2_DAUCA PROLIFERATING CELL NUCLEAR ANTIGEN, LARGE F... 94 1e-18
gi|6319564 Proliferating cell nuclear antigen; Pol30p [Saccharom... 94 2e-18
sp|Q43266|PCNA_MAIZE PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) >... 94 2e-18
sp|O16852|PCNA_SARCR PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (... 94 2e-18
gb|AAG24908.1|AF305075_1 (AF305075) proliferating cell nuclear a... 94 2e-18
sp|P17917|PCNA_DROME PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (... 93 2e-18
sp|Q43124|PCNA_BRANA PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) >... 93 3e-18
gb|AAD19905.1| (AF104412) proliferating cell nuclear antigen II ... 93 3e-18
sp|O82797|PCNA_TOBAC PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) >... 92 4e-18
dbj|BAA33151.1| (AB008186) proliferating cell nuclear antigen [P... 92 4e-18
emb|CAA10108.1| (AJ012662) proliferating cell nuclear antigen [N... 92 4e-18
gb|AAF79566.1|AC022464_24 (AC022464) F22G5.29 [Arabidopsis thali... 92 4e-18
sp|P17070|PCNA_ORYSA PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (... 92 6e-18
sp|O01377|PCNA_BOMMO PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (... 92 6e-18
gb|AAD10528.1| (U87949) proliferating cell nuclear antigen [Zea ... 92 6e-18
dbj|BAA94512.1| (AB041506) proliferating cell nuclear antigen [P... 91 1e-17
gb|AAF40018.1|AF083220_1 (AF083220) proliferating cellular nucle... 91 1e-17
emb|CAB56779.1| (X62976) proliferating cell-nuclear antigen [Dau... 90 2e-17
sp|Q9ZW35|PCNA_ARATH PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) >... 90 3e-17
gb|AAF18324.1|AF140608_1 (AF140608) proliferating cell nuclear a... 89 4e-17
sp|P31008|PCNA_PLAFK PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (... 88 8e-17
sp|Q00268|PCNA_DAUCA PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (... 87 1e-16
pir||S20592 proliferating cell nuclear antigen (clone 4.10) - ca... 86 4e-16
sp|P22177|PCNA_SOYBN PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (... 85 9e-16
gi|9631761 similar to human PCNA, corresponds to Swiss-Prot Acce... 83 2e-15
pir||H71158 hypothetical protein PHS020 - Pyrococcus horikoshii ... 76 3e-13
gb|AAB81177.1| (AF012212) proliferating cell nuclear antigen [Te... 73 3e-12
gb|AAF65548.1|AF242302_1 (AF242302) proliferating cell nuclear a... 71 2e-11
>pir||G75048 proliferating-cell nuclear antigen (pol30) PAB1465 - Pyrococcus
abyssi (strain Orsay) >gi|5458797|emb|CAB50284.1|
(AJ248287) proliferating-cell nuclear antigen (pol30)
[Pyrococcus abyssi]
Length = 249
Score = 482 bits (1227), Expect = e-135
Identities = 249/249 (100%), Positives = 249/249 (100%)
Query: 1 MPFEIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSK 60
MPFEIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSK
Sbjct: 1 MPFEIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSK 60
Query: 61 YEVDGEETIGVNMDHLKKVLKRGKAKETLILRKGEENFLEISLQGTATRTFKLPLIDVEE 120
YEVDGEETIGVNMDHLKKVLKRGKAKETLILRKGEENFLEISLQGTATRTFKLPLIDVEE
Sbjct: 61 YEVDGEETIGVNMDHLKKVLKRGKAKETLILRKGEENFLEISLQGTATRTFKLPLIDVEE 120
Query: 121 IEVDLPELPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLT 180
IEVDLPELPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLT
Sbjct: 121 IEVDLPELPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLT 180
Query: 181 LEDEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLI 240
LEDEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLI
Sbjct: 181 LEDEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLI 240
Query: 241 FLLAPRVEE 249
FLLAPRVEE
Sbjct: 241 FLLAPRVEE 249
>sp|O58398|PCNA_PYRHO PROLIFERATING CELL NUCLEAR ANTIGEN HOMOLOG (PCNA)
>gi|7440027|pir||B71112 probable proliferating-cell
nuclear antigen - Pyrococcus horikoshii
>gi|3257073|dbj|BAA29756.1| (AP000003) 249aa long
hypothetical proliferating-cell nuclear antigen
[Pyrococcus horikoshii]
Length = 249
Score = 460 bits (1171), Expect = e-129
Identities = 231/249 (92%), Positives = 247/249 (98%)
Query: 1 MPFEIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSK 60
MPFEIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLP+SIFSK
Sbjct: 1 MPFEIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPSSIFSK 60
Query: 61 YEVDGEETIGVNMDHLKKVLKRGKAKETLILRKGEENFLEISLQGTATRTFKLPLIDVEE 120
YEVDGEETIGVNMDHLKKVLKRGKAK+TLILRKGEENFLEISLQGTATRTF+LPLIDVEE
Sbjct: 61 YEVDGEETIGVNMDHLKKVLKRGKAKDTLILRKGEENFLEISLQGTATRTFRLPLIDVEE 120
Query: 121 IEVDLPELPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLT 180
IEV+LP+LP+TAKVV+LG+V+KEAVKDASLVSDS+KF+AKENEF MRAEGETQEVEVKLT
Sbjct: 121 IEVELPDLPYTAKVVVLGEVLKEAVKDASLVSDSIKFMAKENEFIMRAEGETQEVEVKLT 180
Query: 181 LEDEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLI 240
LEDEGLLDIEVQEETKSAYG+SYL+DMVKG+GKADEVT++FGNEMPMQMEYYIRDEGRL
Sbjct: 181 LEDEGLLDIEVQEETKSAYGVSYLADMVKGIGKADEVTMRFGNEMPMQMEYYIRDEGRLT 240
Query: 241 FLLAPRVEE 249
FLLAPRVEE
Sbjct: 241 FLLAPRVEE 249
>dbj|BAA33020.2| (AB017486) Proliferation cell nuclear antigen [Pyrococcus furiosus]
Length = 249
Score = 447 bits (1138), Expect = e-125
Identities = 223/249 (89%), Positives = 244/249 (97%)
Query: 1 MPFEIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSK 60
MPFEIVFEGAKEFAQLI+TAS+LIDEAAFKVTE+GISMRAMDPSRVVLIDLNLP+SIFSK
Sbjct: 1 MPFEIVFEGAKEFAQLIDTASKLIDEAAFKVTEDGISMRAMDPSRVVLIDLNLPSSIFSK 60
Query: 61 YEVDGEETIGVNMDHLKKVLKRGKAKETLILRKGEENFLEISLQGTATRTFKLPLIDVEE 120
YEV ETIGVNMDHLKK+LKRGKAK+TLIL+KGEENFLEI++QGTATRTF++PLIDVEE
Sbjct: 61 YEVVEPETIGVNMDHLKKILKRGKAKDTLILKKGEENFLEITIQGTATRTFRVPLIDVEE 120
Query: 121 IEVDLPELPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLT 180
+EVDLPELPFTAKVV+LG+V+K+AVKDASLVSDS+KFIA+ENEF M+AEGETQEVE+KLT
Sbjct: 121 MEVDLPELPFTAKVVVLGEVLKDAVKDASLVSDSIKFIARENEFIMKAEGETQEVEIKLT 180
Query: 181 LEDEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLI 240
LEDEGLLDIEVQEETKSAYG+SYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRL
Sbjct: 181 LEDEGLLDIEVQEETKSAYGVSYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLT 240
Query: 241 FLLAPRVEE 249
FLLAPRVEE
Sbjct: 241 FLLAPRVEE 249
>sp|O73947|PCNA_PYRFU PROLIFERATING CELL NUCLEAR ANTIGEN HOMOLOG (PCNA)
Length = 249
Score = 445 bits (1133), Expect = e-124
Identities = 222/249 (89%), Positives = 243/249 (97%)
Query: 1 MPFEIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSK 60
MPFEIVFEGAKEFAQLI+TAS+LIDEAAFKVTE+GISMRAMDPSRVVLIDLNLP+SIFSK
Sbjct: 1 MPFEIVFEGAKEFAQLIDTASKLIDEAAFKVTEDGISMRAMDPSRVVLIDLNLPSSIFSK 60
Query: 61 YEVDGEETIGVNMDHLKKVLKRGKAKETLILRKGEENFLEISLQGTATRTFKLPLIDVEE 120
YEV ETIGVNMDHLKK+LKRGKAK+TLIL+KGEENFLEI++QGTATRTF++PLIDVEE
Sbjct: 61 YEVVEPETIGVNMDHLKKILKRGKAKDTLILKKGEENFLEITIQGTATRTFRVPLIDVEE 120
Query: 121 IEVDLPELPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLT 180
+EVDLPELPFTAKVV+LG+V+K+AVKDASLVSD +KFIA+ENEF M+AEGETQEVE+KLT
Sbjct: 121 MEVDLPELPFTAKVVVLGEVLKDAVKDASLVSDCIKFIARENEFIMKAEGETQEVEIKLT 180
Query: 181 LEDEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLI 240
LEDEGLLDIEVQEETKSAYG+SYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRL
Sbjct: 181 LEDEGLLDIEVQEETKSAYGVSYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLT 240
Query: 241 FLLAPRVEE 249
FLLAPRVEE
Sbjct: 241 FLLAPRVEE 249
>emb|CAB59006.1| (AJ130939) proliferating cell nuclear antigen (PCNA) [Thermococcus
fumicolans]
Length = 249
Score = 429 bits (1092), Expect = e-119
Identities = 210/249 (84%), Positives = 238/249 (95%)
Query: 1 MPFEIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSK 60
MPFEIVF+GAKEFA LI TAS LIDEAAFKVT+EGISMRAMDPSRVVLIDLNLP SIFSK
Sbjct: 1 MPFEIVFDGAKEFADLIATASNLIDEAAFKVTDEGISMRAMDPSRVVLIDLNLPESIFSK 60
Query: 61 YEVDGEETIGVNMDHLKKVLKRGKAKETLILRKGEENFLEISLQGTATRTFKLPLIDVEE 120
YEV+ EETIG+NMDH KK+LKRGK K+TLIL+KG+ENFLEI+ +GTA RTF+LPLIDVEE
Sbjct: 61 YEVEEEETIGINMDHFKKILKRGKGKDTLILKKGDENFLEITFEGTAKRTFRLPLIDVEE 120
Query: 121 IEVDLPELPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLT 180
+E+DLPELPFTAKVV+LG+V+KEAVKDASLVSD+MKFIAKENEF+MRAEGET EVE+KLT
Sbjct: 121 LELDLPELPFTAKVVLLGEVLKEAVKDASLVSDAMKFIAKENEFSMRAEGETNEVEIKLT 180
Query: 181 LEDEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLI 240
LEDEGLLDIEV+EETKSAYGISYL+DMVKG+GKADEVTI+FGNEMP+QM+Y+IRDEG+L
Sbjct: 181 LEDEGLLDIEVEEETKSAYGISYLADMVKGIGKADEVTIRFGNEMPLQMDYFIRDEGKLT 240
Query: 241 FLLAPRVEE 249
FLLAPRVE+
Sbjct: 241 FLLAPRVED 249
>sp|Q57697|PCNA_METJA PROLIFERATING CELL NUCLEAR ANTIGEN HOMOLOG (PCNA)
>gi|2129221|pir||H64330 proliferating-cell nuclear
antigen homolog - Methanococcus jannaschii
>gi|1590980|gb|AAB98235.1| (U67480) proliferating-cell
nuclear antigen (pol30) [Methanococcus jannaschii]
Length = 247
Score = 201 bits (506), Expect = 6e-51
Identities = 106/247 (42%), Positives = 152/247 (60%), Gaps = 3/247 (1%)
Query: 3 FEIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYE 62
F V E AKEF ++++T S L+DE F+V EEGI AMDPS V L+ L +P F +YE
Sbjct: 2 FRGVMESAKEFKKVVDTISTLLDEICFEVDEEGIKASAMDPSHVALVSLEIPRLAFEEYE 61
Query: 63 VDGEETIGVNMDHLKKVLKRGKAKETLILRKGEE-NFLEISLQGTATRTFKLPLIDVEEI 121
D + IG++++ KKV+ R KAK+ LIL EE N L + + T R F L L+D+
Sbjct: 62 ADSHD-IGIDLEAFKKVMNRAKAKDRLILELDEEKNKLNVIFENTGKRKFSLALLDISAS 120
Query: 122 EVDLPELPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTL 181
V +PE+ + ++I GD KEA+KDA L SD + A E++F + A+G+ E E
Sbjct: 121 SVKVPEIEYPNVIMIKGDAFKEALKDADLFSDYVILKADEDKFVIHAKGDLNENEAIFEK 180
Query: 182 EDEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIF 241
+ ++ +EV+EE KSA+ + YL DMVKG+ D + I GN+MP+++EY I L F
Sbjct: 181 DSSAIISLEVKEEAKSAFNLDYLMDMVKGVSSGDIIKIYLGNDMPLKLEYSIAGV-NLTF 239
Query: 242 LLAPRVE 248
LLAPR+E
Sbjct: 240 LLAPRIE 246
>pir||G72771 probable Proliferating call nuclear antigen homolog APE0162 -
Aeropyrum pernix (strain K1) >gi|5103552|dbj|BAA79073.1|
(AP000058) 263aa long hypothetical Proliferating call
nuclear antigen homolog [Aeropyrum pernix]
Length = 263
Score = 151 bits (377), Expect = 8e-36
Identities = 86/243 (35%), Positives = 144/243 (58%), Gaps = 11/243 (4%)
Query: 10 AKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGE--- 66
AK F +L+++ S+++DE F +T EG+ +R MDP+RV L+D+ +P+S F + + G+
Sbjct: 22 AKVFKELVDSVSKILDEGLFIITGEGLRLRGMDPARVALVDIEIPSSSFFDFYMAGDVER 81
Query: 67 ETIGVNMDHLKKVLKRGKAKETLILRKGEENFLEISLQGTATRTFKLPLIDVEEIEVDLP 126
+GVNM+ LK V+ R K + L +R E+ L I ++ R + LP + E+ VD+P
Sbjct: 82 VELGVNMETLKGVVARAKKGDQLEVRVREDKVLFI-VESVVLRRYLLPNL---EVIVDVP 137
Query: 127 E---LPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEG-ETQEVEVKLTLE 182
E L F A ++ DV+K+ ++D LV D ++F A E+ ++R+ G E + VE +LT E
Sbjct: 138 EDISLEFDATATVIADVVKKTLRDVELVGDIVEFDAGEDYLSIRSVGPERRRVETRLTRE 197
Query: 183 DEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFL 242
L+D+EV+E S Y + YL M+ A+ + + F + P++M + D R+ +L
Sbjct: 198 SPALIDLEVKEPATSRYDVGYLKRMLGVAKIAESIELSFSTDKPLKMVFKSPDGSRVTYL 257
Query: 243 LAP 245
LAP
Sbjct: 258 LAP 260
>gb|AAK40734.1| Proliferating cell nuclear antigen homolog (PCNA) (pcnA-1)
[Sulfolobus solfataricus]
Length = 259
Score = 151 bits (377), Expect = 8e-36
Identities = 77/244 (31%), Positives = 140/244 (56%), Gaps = 1/244 (0%)
Query: 4 EIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEV 63
++V++ + +I+ +RL+DEA K ++ + + A+D + + LI +NLP +F +Y+V
Sbjct: 17 KVVYDDVRVLKDIIQALARLVDEAVLKFKQDSVELVALDRAHISLISVNLPREMFKEYDV 76
Query: 64 DGEETIGVNMDHLKKVLKRGKAKETLILRKGEENFLEISLQGTATRTFKLPLIDVEEIEV 123
+ E G N +L K+LK K KE + + + + I++ G+ R F + ++V E E+
Sbjct: 77 NDEFKFGFNTQYLMKILKVAKRKEAIEIASESPDSVIINIIGSTNREFNVRNLEVSEQEI 136
Query: 124 DLPELPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTLED 183
L F I D K A+ + S V+D++ E+ ++AEGE+ EVEV+ + +
Sbjct: 137 PEINLQFDISATISSDGFKSAISEVSTVTDNVVVEGHEDRILIKAEGES-EVEVEFSKDT 195
Query: 184 EGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLL 243
GL D+E +E+K++Y YL D++ +D V I FGN+ P+Q+ + + G++ +LL
Sbjct: 196 GGLQDLEFSKESKNSYSAEYLDDVLSLTKLSDYVKISFGNQKPLQLFFNMEGGGKVTYLL 255
Query: 244 APRV 247
AP+V
Sbjct: 256 APKV 259
>pir||E72738 probable proliferating cell nuclear antigen APE0441 - Aeropyrum
pernix (strain K1) >gi|5104085|dbj|BAA79401.1|
(AP000059) 233aa long hypothetical proliferating cell
nuclear antigen [Aeropyrum pernix]
Length = 233
Score = 141 bits (351), Expect = 9e-33
Identities = 72/234 (30%), Positives = 133/234 (56%), Gaps = 2/234 (0%)
Query: 16 LIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEET-IGVNMD 74
++ + ++I+E F T EG+S+RA+D S V ++DL P + F +Y++ GE GV+ D
Sbjct: 1 MVASIEKIIEEGVFVATGEGLSLRALDTSHVAMVDLYYPNTAFIEYDIGGESVEFGVSFD 60
Query: 75 HLKKVLKRGKAKETLILRKGEENFLEISLQGTATRTFKLPLIDVEEIEVDLPELPFTAKV 134
L KVL+R + ++ L+L E + L + L+ RTF++P + + ++ P++ FT +
Sbjct: 61 LLSKVLRRARKEDELVLEV-EGSRLAVKLKSRGERTFRIPQVVMTYEKLPEPKVSFTVRA 119
Query: 135 VILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTLEDEGLLDIEVQEE 194
+LG +EAV+D S+++ A E+ + E VE++L+ LLD E + +
Sbjct: 120 RMLGSTFREAVRDLEPHSETLTLRALEDALLLVGSSEMATVEIELSQSRGSLLDYEAESQ 179
Query: 195 TKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLAPRVE 248
+++Y I Y S+M+ AD V + F + P++++ GRL F ++P++E
Sbjct: 180 DRASYSIEYFSEMLSAAQAADAVVVSFSEDAPVRVDMEYLGGGRLTFYVSPKIE 233
>gb|AAK41309.1| Proliferating cell nuclear antigen homolog (PCNA) (pcnA-2)
[Sulfolobus solfataricus]
Length = 246
Score = 129 bits (322), Expect = 2e-29
Identities = 75/240 (31%), Positives = 131/240 (54%), Gaps = 3/240 (1%)
Query: 10 AKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGE-ET 68
A F+ ++ T + EA F VT+EGI + +DPSRVV +D+ LP+S F +EV E E
Sbjct: 9 AVSFSYILRTVGDFLSEANFIVTKEGIRVSGIDPSRVVFLDIFLPSSYFEGFEVSQEKEI 68
Query: 69 IGVNMDHLKKVLKRGKAKETLILRKGEENFLEISLQGTATRTFKLPLIDVEEIEVDLPEL 128
IG ++ + +LKR +TLIL E L ++ G TR+F+LPLI VE + L
Sbjct: 69 IGFKLEDVNDILKRVLKDDTLILSSNESK-LTLTFDGEFTRSFELPLIQVESTQPPSVNL 127
Query: 129 PFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTLEDEGLLD 188
F K +L + + + S + + + +KEN+ G+ +V+L+ ++ LL+
Sbjct: 128 EFPFKAQLLTITFADIIDELSDLGEVLNIHSKENKLYFEVIGDLSTAKVELSTDNGTLLE 187
Query: 189 IEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLAPRVE 248
+ S+YG+ Y+++ K +D + + FG+++P+++ + + EG F +APR +
Sbjct: 188 AS-GADVSSSYGMEYVANTTKMRRASDSMELYFGSQIPLKLRFKLPQEGYGDFYIAPRAD 246
>sp|O27367|PCNA_METTH PROLIFERATING CELL NUCLEAR ANTIGEN HOMOLOG (PCNA)
>gi|7440025|pir||D69041 proliferating-cell nuclear
antigen - Methanobacterium thermoautotrophicum (strain
Delta H) >gi|2622417|gb|AAB85790.1| (AE000895)
proliferating-cell nuclear antigen [Methanobacterium
thermoautotrophicum]
Length = 244
Score = 129 bits (320), Expect = 4e-29
Identities = 73/232 (31%), Positives = 125/232 (53%), Gaps = 8/232 (3%)
Query: 18 ETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMDHLK 77
+ S ++DE +++ EG+ + A+D S + + L L A +F +Y D E I V+ + L
Sbjct: 17 DAISSIVDEVQIQLSAEGLRLDALDRSHITYVHLELKAELFDEYVCDEPERINVDTEELM 76
Query: 78 KVLKRGKAKETLILRKGEENFLEISLQGTATRTFKLPLIDVEEIEVDLPELPFTAKVVIL 137
KVLKR KA + +IL E N + I +G A RTFK+ LID+E PE+ + + +
Sbjct: 77 KVLKRAKANDRVILSTDEGNLI-IQFEGEAVRTFKIRLIDIEYETPSPPEIEYENEFEVP 135
Query: 138 GDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTLEDEGLLDIEVQEETKS 197
++K+++ D + SD + F E+ F AEGE + ++ E L + + +S
Sbjct: 136 FQLLKDSIADIDIFSDKITFRVDEDRFIASAEGEFGDAQI------EYLHGERIDKPARS 189
Query: 198 AYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRD-EGRLIFLLAPRVE 248
Y + + +M+K ++ I G++MP+++ + EG L FLLAPR+E
Sbjct: 190 IYSLDKIKEMLKADKFSETAIINLGDDMPLKLTLKMASKEGELSFLLAPRIE 241
>emb|CAB93143.1| (AJ278286) proliferating cell nuclear antigen [Haloarcula
marismortui]
Length = 256
Score = 127 bits (317), Expect = 9e-29
Identities = 83/238 (34%), Positives = 137/238 (56%), Gaps = 13/238 (5%)
Query: 17 IETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMDHL 76
+++ S L+DE + E+G+ +RA+DP+ V ++DL L A+ F YE DG IGVN+ L
Sbjct: 24 LDSVSVLVDECKIHLEEDGLEIRAVDPANVGMVDLRLDAAAFESYETDG-GLIGVNLSRL 82
Query: 77 KKVLKRGKAKETLILRKGEE-NFLEISLQGTATRTFKLPLIDVEEI--EVDLPELPFTAK 133
+ + A + + L EE L IS+ G + L LID + I E DLP+L +A
Sbjct: 83 EDIAGMADAGQLVHLDLDEETRKLHISIDGL---EYTLALIDPDSIRQEPDLPDLDLSAN 139
Query: 134 VVILGDVIKEAVKDASLVSD--SMKFIAKENEFTMRAEGETQEVEVKLTLEDEGLLDIEV 191
+VI G I +V A +VSD ++ A + F + AEG+T +V ++LT +D L+D+
Sbjct: 140 IVIEGKDIDRSVTAADMVSDHIALGVDATDELFYVDAEGDTDDVHLELTRDD--LIDL-T 196
Query: 192 QEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEY-YIRDEGRLIFLLAPRVE 248
+ S + + YL +M K + K EV ++ G E P++M + + +GR+ ++LAPR++
Sbjct: 197 PGDAHSLFSLDYLKNMNKAIPKDAEVEMELGEEFPVKMHFSFAEGQGRVTYMLAPRIQ 254
>gb|AAG20376.1| (AE005110) proliferating-cell nuclear antigen; Pcn [Halobacterium
sp. NRC-1]
Length = 247
Score = 118 bits (294), Expect = 5e-26
Identities = 80/245 (32%), Positives = 135/245 (54%), Gaps = 13/245 (5%)
Query: 10 AKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETI 69
A + +++ S L+DE + ++ +S+RA+DP+ V ++DL+L A+ F YE DG I
Sbjct: 8 ADTLQETLDSVSVLVDECKIHLDDDTLSIRAVDPASVGMVDLDLAATAFESYEADG-GLI 66
Query: 70 GVNMDHLKKVLKRGKAKETLILRKGEE-NFLEISLQGTATRTFKLPLIDVEEI--EVDLP 126
GVN+ L+ + A + + L EE L I + G + L LID + I E D+P
Sbjct: 67 GVNLSRLEDIAGMADAGQLIQLELDEETRKLHIQIDGL---EYTLALIDPDSIRQEPDIP 123
Query: 127 ELPFTAKVVILGDVIKEAVKDASLVSD--SMKFIAKENEFTMRAEGETQEVEVKLTLEDE 184
+L A V I G I AV A +VSD ++ ++ F + AEG+T +V L L +
Sbjct: 124 DLDLPAHVAIEGRDIDRAVTAADMVSDHIALGVDTGDDLFYVNAEGDTDDVH--LELAPD 181
Query: 185 GLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRD-EGRLIFLL 243
L+D++ + S + + YL DM K + EV ++ G+E P+++ + I D +G + ++L
Sbjct: 182 QLIDLDA-GDAHSLFSLDYLKDMNKAIPTTAEVELELGDEFPIKLHFDIADAQGHVTYML 240
Query: 244 APRVE 248
APR++
Sbjct: 241 APRIQ 245
>pir||A72526 hypothetical protein APE2182 - Aeropyrum pernix (strain K1)
>gi|5105881|dbj|BAA81193.1| (AP000063) 251aa long
hypothetical protein [Aeropyrum pernix]
Length = 251
Score = 116 bits (287), Expect = 3e-25
Identities = 71/247 (28%), Positives = 125/247 (49%), Gaps = 5/247 (2%)
Query: 3 FEIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYE 62
F +V+ + +F + +T +++ DE F+ + +G+ M P + L L +P+ F +Y
Sbjct: 2 FRLVYTASSKFKYIAQTLAKINDEGVFEFSLDGLRAWIMSPDKTSLAILEMPSLSFEEYM 61
Query: 63 VDGEETIGVNMDHLKKVLKRGKAKETLILR-KGEENFLEISLQGTA---TRTFKLPLIDV 118
V+ E + + D L K+ KR + +I + EE LE+ L+ +R F +P V
Sbjct: 62 VEEEMRVVLRTDELNKISKRATRNDDIIFQWNAEEQALEVELRDRKLGFSRKFLVPATSV 121
Query: 119 EEIEVDLPELPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVK 178
E+ +L T IL D +K ++D +V D +F A E + +R++ E +E E
Sbjct: 122 GAEEMRRLKLEPTVSFTILTDDLKAMIQDVKVVGDFAEFEASEGQVVVRSQAEEKEYEWV 181
Query: 179 LTLEDEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGR 238
+ D LL +EV+E+ KS Y L K +G A+ V + F ++ PM++EY + R
Sbjct: 182 MKPGDV-LLSLEVEEDAKSIYSRQVLEIATKPVGAAESVKVSFASDYPMKIEYTFPNGER 240
Query: 239 LIFLLAP 245
+ +AP
Sbjct: 241 MELYMAP 247
>emb|CAC12046.1| (AL445065) proliferating cell nuclear antigen (PCNA) related
protein [Thermoplasma acidophilum]
Length = 271
Score = 111 bits (274), Expect = 1e-23
Identities = 68/245 (27%), Positives = 131/245 (52%), Gaps = 13/245 (5%)
Query: 11 KEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIG 70
K ++ + S ++ EA F+V E G+S+ A+DP+ V +I L +P F ++ DG+E I
Sbjct: 34 KNLKEITDLLSTIVSEAKFRVDENGMSVTAVDPAHVAMIRLEVPKEAFVEFHTDGQEEIA 93
Query: 71 VNMDHLKKVLKRGKAKETL-ILRKGEENFLEISLQGTATRTFKLPLIDVEEIEV-DLPEL 128
+++D LK V++ + E + I + GE+ E+ GT ++ + L+D I +P +
Sbjct: 94 LDIDRLKSVIRLASSSENVGITKDGEKLKFEL---GTINKS--ISLLDPSTIVTPKIPNI 148
Query: 129 PFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTLEDEGLLD 188
V+ + ++ A +SDS++F ++ F + E++E E + L + + D
Sbjct: 149 TSEYYAVLKKSDFERGLRAAEDISDSIRFTLSQDGFKAYSHSESEESE--MILPKDLITD 206
Query: 189 IEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYI-RDEGRLI---FLLA 244
+ KS+Y + YL +K + D + + F ++ P+ +E+Y+ ++ G I FLLA
Sbjct: 207 MSCNTTIKSSYPLEYLLKFIKAISSTDSLKLSFRDDYPLSVEFYLDQNPGAKIKGLFLLA 266
Query: 245 PRVEE 249
PR+E+
Sbjct: 267 PRMEQ 271
>gi|11497947 proliferating-cell nuclear antigen (pol30) [Archaeoglobus fulgidus]
>gi|7440023|pir||G69291 proliferating-cell nuclear
antigen (pol30) homolog - Archaeoglobus fulgidus
>gi|2650299|gb|AAB90899.1| (AE001081) proliferating-cell
nuclear antigen (pol30) [Archaeoglobus fulgidus]
Length = 245
Score = 108 bits (268), Expect = 5e-23
Identities = 68/241 (28%), Positives = 128/241 (52%), Gaps = 13/241 (5%)
Query: 15 QLIETASR----LIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIG 70
+L++T +R L+ EA E+G+ RA+DP+ V ++ +++P F Y +D E+TIG
Sbjct: 9 ELLKTVTRAIVALVSEARIHFLEKGLHSRAVDPANVAMVIVDIPKDSFEVYNIDEEKTIG 68
Query: 71 VNMDHLKKVLKRGKAKETLILRKGEENFLEISLQGTATRTFKLPLIDVEEI--EVDLPEL 128
V+MD + + K K+ + L +E+ L++ + +K+ LID I E +PEL
Sbjct: 69 VDMDRIFDISKSISTKDLVELIVEDESTLKVKF---GSVEYKVALIDPSAIRKEPRIPEL 125
Query: 129 PFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTLEDEGLLD 188
AK+V+ K+A+ A +SD + F + + F + A+G+ + +T + L++
Sbjct: 126 ELPAKIVMDAGEFKKAIAAADKISDQVIFRSDKEGFRIEAKGDVDSIVFHMT--ETELIE 183
Query: 189 IEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEY-YIRDEGRLIFLLAPRV 247
E +S + + YL + K G D +TI G P+++ + + ++ ++LAPR+
Sbjct: 184 FN-GGEARSMFSVDYLKEFCKVAGSGDLLTIHLGTNYPVRLVFELVGGRAKVEYILAPRI 242
Query: 248 E 248
E
Sbjct: 243 E 243
>dbj|BAA92700.1| (AB039962) proliferating cell nuclear antigen subtype1 [Xenopus
laevis] >gi|7248367|dbj|BAA92701.1| (AB039963)
proliferating cell nuclear antigen subtype2 [Xenopus
laevis] >gi|7248369|dbj|BAA92702.1| (AB039964)
proliferating cell nuclear antigen subtype3 [Xenopus
laevis]
Length = 261
Score = 103 bits (254), Expect = 2e-21
Identities = 63/245 (25%), Positives = 122/245 (49%), Gaps = 11/245 (4%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E LIDEA + +T GIS+++MD S V L+ L L + F Y D ++IGV M
Sbjct: 14 KVLEALKDLIDEACWDITSSGISLQSMDSSHVSLVQLTLRSDGFDTYRCDRNQSIGVKMS 73
Query: 75 HLKKVLKRGKAKETLILRKGEENFLEISL-----QGTATRTFKLPLIDVEEIEVDLPELP 129
+ K+LK A E +I + E+N +++ +++ L+D++ ++ +PE
Sbjct: 74 SMSKILKCA-AGEDIITLRAEDNADTVTMVFESPNQEKVSDYEMKLMDLDVEQLGIPEQE 132
Query: 130 FTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTL-----EDE 184
++ + + +D S + D++ ++ A GE VKL+ ++E
Sbjct: 133 YSCVIKMPSGEFARICRDLSQIGDAVVISCAKDGVKFSASGELGTGNVKLSQTSNVDKEE 192
Query: 185 GLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLA 244
+ IE+ E + + + YL+ K + V + ++P+ +EY I D G + + LA
Sbjct: 193 EAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVILSMSADIPLVVEYKIADMGHVKYYLA 252
Query: 245 PRVEE 249
P++E+
Sbjct: 253 PKIED 257
>pir||I48707 proliferating cell nuclear antigen - mouse
>gi|53600|emb|CAA37243.1| (X53068) proliferating cell
nuclear antigen (AA 1-261) [Mus musculus]
Length = 261
Score = 101 bits (250), Expect = 7e-21
Identities = 63/245 (25%), Positives = 122/245 (49%), Gaps = 11/245 (4%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E LI+EA + V+ G+++++MD S V L+ L L + F Y D T+GVN+
Sbjct: 14 KVLEALKDLINEACWDVSSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLTMGVNLT 73
Query: 75 HLKKVLKRGKAKETLILRKGEENFLEISLQGTA-----TRTFKLPLIDVEEIEVDLPELP 129
+ K+LK E +I + E+N ++L A +++ L+D++ ++ +PE
Sbjct: 74 SMSKILKCA-GNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQE 132
Query: 130 FTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTL-----EDE 184
++ + + +D S + D++ +N A GE +KL+ ++E
Sbjct: 133 YSCVIKMPSGEFARICRDLSHIGDAVVISCAKNGVKFSASGELGNGNIKLSQTSNVDKEE 192
Query: 185 GLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLA 244
+ IE+ E + + YL+ K + VT+ ++P+ +EY I D G L + LA
Sbjct: 193 EAVTIEMNEPVHLTFALRYLNFFTKATPLSPTVTLSMSADVPLVVEYKIADMGHLKYYLA 252
Query: 245 PRVEE 249
P++E+
Sbjct: 253 PKIED 257
>gi|9627791 proliferating cell nuclear antigen [Autographa californica
nucleopolyhedrovirus] >gi|129696|sp|P11038|PCNA_NPVAC
PROLIFERATING CELL NUCLEAR ANTIGEN (ECORI-T SITE PROTEIN
ETL) >gi|70826|pir||WMNVET EcoRI-T large (ETL) Ac-pcna
protein - Autographa californica nuclear polyhedrosis
virus >gi|332419|gb|AAA21097.1| (M20718) EcoRI-T large;
(ETL) protein [Autographa californica
nucleopolyhedrovirus] >gi|4376186|gb|AAA66679.2|
(L22858) proliferating cell nuclear antigen [Autographa
californica nucleopolyhedrovirus]
Length = 256
Score = 101 bits (248), Expect = 1e-20
Identities = 64/249 (25%), Positives = 114/249 (45%), Gaps = 6/249 (2%)
Query: 3 FEIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYE 62
FE F+ +L+ET L+ A F G+SM+ MD S V L+ L L A F KY
Sbjct: 2 FEAEFKTGAVLKRLVETFKDLLPHATFDCDNRGVSMQVMDTSHVALVSLQLHAEGFKKYR 61
Query: 63 VDGEETIGVNMDHLKKVLKRGKAKETLILRKGEEN----FLEISLQGTATRTFKLPLIDV 118
D + V+++ L K++K + +++++ ++ F+ + T T KL IDV
Sbjct: 62 CDRNVPLNVSINSLSKIVKCVNERSSVLMKAEDQGDVMAFVFNNDNRICTYTLKLMCIDV 121
Query: 119 EEIEVDLPELPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVK 178
E + +P+ + V + + KD + + + RA G+ +V+
Sbjct: 122 EHL--GIPDSDYDCVVHMSSVEFAQVCKDMTQFDHDIIVSCSKKGLQFRANGDIGSADVQ 179
Query: 179 LTLEDEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGR 238
++ ++E ++ ++ + YL K A VTI E+P ++EY I+D G
Sbjct: 180 MSADNENFSVLKAKQTVTHTFAGDYLCHFAKAAPLAPTVTIYMSEELPFKLEYCIKDVGV 239
Query: 239 LIFLLAPRV 247
L LAP++
Sbjct: 240 LACFLAPKI 248
>gb|AAK40726.1| Proliferating cell nuclear antigen putative homolog (PCNA-like)
(pcnA-like) [Sulfolobus solfataricus]
Length = 249
Score = 99.8 bits (245), Expect = 3e-20
Identities = 59/249 (23%), Positives = 121/249 (47%), Gaps = 5/249 (2%)
Query: 3 FEIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYE 62
F+IV+ AK+F I + + + D TE+GI R + +V++ + +P + S+Y
Sbjct: 2 FKIVYPNAKDFFSFINSITNVTDSIILNFTEDGIFSRHLTEDKVLMAIMRIPKDVLSEYS 61
Query: 63 VDGEETIGVNMDHLKKVLKRGKAKETLILRKGEENFLEISLQGTATRTFKLPLIDVEEIE 122
+D ++ +++ +KK+L + +K+ I ++ L+I ++ + I E+ +
Sbjct: 62 IDSPTSVKLDVSSVKKILSKASSKKATIELTETDSGLKIIIRDEKSGAKSTIYIKAEKGQ 121
Query: 123 VDL---PELPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKL 179
V+ P++ V+ D +LV + M+ +E++ + A GE + V
Sbjct: 122 VEQLTEPKVNLAVNFTTDESVLNVIAADVTLVGEEMRISTEEDKIKIEA-GEEGKRYVAF 180
Query: 180 TLEDEGLLDIEVQEETKSAYGISYLSDMVKGL-GKADEVTIKFGNEMPMQMEYYIRDEGR 238
++D+ L ++ + S+Y D VKGL G + + FG +PM+++ G
Sbjct: 181 LMKDKPLKELSIDTSASSSYSAEMFKDAVKGLRGFSAPTMVSFGENLPMKIDVEAVSGGH 240
Query: 239 LIFLLAPRV 247
+IF +APR+
Sbjct: 241 MIFWIAPRL 249
>gi|7242171 proliferating cell nuclear antigen [Mus musculus]
>gi|129695|sp|P17918|PCNA_MOUSE PROLIFERATING CELL
NUCLEAR ANTIGEN (PCNA) (CYCLIN) >gi|319907|pir||WMMS
proliferating cell nuclear antigen - mouse
>gi|53602|emb|CAA40938.1| (X57800) proliferating cell
nuclear antigen (DNA polymerase delta auxiliary
protein) [Mus musculus]
Length = 261
Score = 99.8 bits (245), Expect = 3e-20
Identities = 62/245 (25%), Positives = 121/245 (49%), Gaps = 11/245 (4%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E LI+EA + V+ G+++++MD S V L+ L L + F Y D +GVN+
Sbjct: 14 KVLEALKDLINEACWDVSSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLT 73
Query: 75 HLKKVLKRGKAKETLILRKGEENFLEISLQGTA-----TRTFKLPLIDVEEIEVDLPELP 129
+ K+LK E +I + E+N ++L A +++ L+D++ ++ +PE
Sbjct: 74 SMSKILKCA-GNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQE 132
Query: 130 FTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTL-----EDE 184
++ + + +D S + D++ +N A GE +KL+ ++E
Sbjct: 133 YSCVIKMPSGEFARICRDLSHIGDAVVISCAKNGVKFSASGELGNGNIKLSQTSNVDKEE 192
Query: 185 GLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLA 244
+ IE+ E + + YL+ K + VT+ ++P+ +EY I D G L + LA
Sbjct: 193 EAVTIEMNEPVHLTFALRYLNFFTKATPLSPTVTLSMSADVPLVVEYKIADMGHLKYYLA 252
Query: 245 PRVEE 249
P++E+
Sbjct: 253 PKIED 257
>gi|4505641 proliferating cell nuclear antigen [Homo sapiens]
>gi|11421166|ref|XP_009571.1| proliferating cell nuclear
antigen [Homo sapiens] >gi|129694|sp|P12004|PCNA_HUMAN
PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (CYCLIN)
>gi|70823|pir||WMHUET proliferating cell nuclear antigen
- human >gi|2914383|pdb|1AXC|A Chain A, Human Pcna
>gi|181272|gb|AAA35736.1| (M15796) cyclin [Homo sapiens]
>gi|387005|gb|AAA60040.1| (J04718) proliferating cell
nuclear antigen (PCNA) [Homo sapiens]
Length = 261
Score = 99.8 bits (245), Expect = 3e-20
Identities = 61/245 (24%), Positives = 122/245 (48%), Gaps = 11/245 (4%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E LI+EA + ++ G+++++MD S V L+ L L + F Y D +GVN+
Sbjct: 14 KVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLT 73
Query: 75 HLKKVLKRGKAKETLILRKGEENFLEISLQGTA-----TRTFKLPLIDVEEIEVDLPELP 129
+ K+LK E +I + E+N ++L A +++ L+D++ ++ +PE
Sbjct: 74 SMSKILKCA-GNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQE 132
Query: 130 FTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTL-----EDE 184
++ V + +D S + D++ ++ A GE +KL+ ++E
Sbjct: 133 YSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEE 192
Query: 185 GLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLA 244
+ IE+ E + + + YL+ K + VT+ ++P+ +EY I D G L + LA
Sbjct: 193 EAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLA 252
Query: 245 PRVEE 249
P++E+
Sbjct: 253 PKIED 257
>sp|P18248|PCNA_XENLA PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (CYCLIN)
>gi|280684|pir||A37357 proliferating cell nuclear
antigen - African clawed frog >gi|214647|gb|AAA49926.1|
(M34080) proliferating cell nuclear antigen (PCNA)
[Xenopus laevis]
Length = 261
Score = 99.8 bits (245), Expect = 3e-20
Identities = 61/245 (24%), Positives = 121/245 (48%), Gaps = 11/245 (4%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E LIDEA + +T GIS+++MD S V L+ L L + F Y D ++IGV M
Sbjct: 14 KVLEALKDLIDEACWDITSSGISLQSMDSSHVSLVQLTLRSDGFDTYRCDRNQSIGVKMS 73
Query: 75 HLKKVLKRGKAKETLILRKGEENFLEISL-----QGTATRTFKLPLIDVEEIEVDLPELP 129
+ K+LK A + +I + E+N +++ +++ L+D++ ++ +PE
Sbjct: 74 SMSKILKCA-ASDDIITLRAEDNADTVTMVFESPNQEKVSDYEMKLMDLDVEQLGIPEQE 132
Query: 130 FTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTL-----EDE 184
++ + + +D S + D++ ++ A GE VKL+ ++E
Sbjct: 133 YSCVIKMPSGEFARICRDLSQIGDAVVISCAKDGVKFSASGELGTGNVKLSQTSNVDKEE 192
Query: 185 GLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLA 244
+ IE+ E + + + YL+ K + V + ++P+ +EY I D + + LA
Sbjct: 193 EAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVILSMSADIPLVVEYKIADMEHVKYYLA 252
Query: 245 PRVEE 249
P++E+
Sbjct: 253 PKIED 257
>pdb|1AXC|E Chain E, Human Pcna >gi|2914385|pdb|1AXC|C Chain C, Human Pcna
Length = 261
Score = 99.8 bits (245), Expect = 3e-20
Identities = 61/245 (24%), Positives = 122/245 (48%), Gaps = 11/245 (4%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E LI+EA + ++ G+++++MD S V L+ L L + F Y D +GVN+
Sbjct: 14 KVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLT 73
Query: 75 HLKKVLKRGKAKETLILRKGEENFLEISLQGTA-----TRTFKLPLIDVEEIEVDLPELP 129
+ K+LK E +I + E+N ++L A +++ L+D++ ++ +PE
Sbjct: 74 SMSKILKCA-GNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQE 132
Query: 130 FTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTL-----EDE 184
++ V + +D S + D++ ++ A GE +KL+ ++E
Sbjct: 133 YSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEE 192
Query: 185 GLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLA 244
+ IE+ E + + + YL+ K + VT+ ++P+ +EY I D G L + LA
Sbjct: 193 EAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLA 252
Query: 245 PRVEE 249
P++E+
Sbjct: 253 PKIED 257
>dbj|BAA77390.1| (AB025357) proliferating cell nuclear antigen [Anguilla japonica]
Length = 260
Score = 99.5 bits (244), Expect = 3e-20
Identities = 62/245 (25%), Positives = 122/245 (49%), Gaps = 11/245 (4%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E LI EA + V+ GIS+++MD S V L+ L L + F Y D +GV+++
Sbjct: 14 KVLEALKDLITEACWDVSSSGISLQSMDSSHVSLVQLTLRSDGFDSYRCDRNLALGVSLN 73
Query: 75 HLKKVLKRGKAKETLILRKGEEN-----FLEISLQGTATRTFKLPLIDVEEIEVDLPELP 129
+ K+LK E +I + E+N + +L +++ L+D++ ++ +PE
Sbjct: 74 SMSKMLKCA-GNEDIITLRAEDNADTLALVFETLNQEKVSDYEMKLMDLDVEQLGIPEQE 132
Query: 130 FTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTL-----EDE 184
++ V + +D S + D++ ++ A GE VKL+ E++
Sbjct: 133 YSCVVKMPSGEFARICRDLSQIGDAVMISCAKDGVMFSASGELGTGNVKLSQTSNVDEED 192
Query: 185 GLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLA 244
+ IE+ E + + ++YL+ K + VT+ ++P+ +EY I D G + + LA
Sbjct: 193 DAVTIEMNEPVQLIFALNYLNFFTKATPLSKTVTLSMSADIPLVVEYKIADMGHVKYYLA 252
Query: 245 PRVEE 249
P+++E
Sbjct: 253 PKIDE 257
>gb|AAG10077.1|AF294427_1 (AF294427) proliferating cell nuclear antigen [Cricetulus griseus]
Length = 261
Score = 99.5 bits (244), Expect = 3e-20
Identities = 61/245 (24%), Positives = 122/245 (48%), Gaps = 11/245 (4%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E LI+EA + ++ G+++++MD S V L+ L L + F Y D +GVN+
Sbjct: 14 KVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLT 73
Query: 75 HLKKVLKRGKAKETLILRKGEENFLEISLQGTA-----TRTFKLPLIDVEEIEVDLPELP 129
+ K+LK E +I + E+N ++L A +++ L+D++ ++ +PE
Sbjct: 74 SMSKILKCA-GNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQE 132
Query: 130 FTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTL-----EDE 184
++ V + +D S + D++ ++ A GE +KL+ ++E
Sbjct: 133 YSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEE 192
Query: 185 GLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLA 244
+ IE+ E + + + YL+ K + VT+ ++P+ +EY I D G L + LA
Sbjct: 193 EAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSTDVPLVVEYKISDMGHLKYYLA 252
Query: 245 PRVEE 249
P++E+
Sbjct: 253 PKIED 257
>sp|P04961|PCNA_RAT PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (CYCLIN)
>gi|70824|pir||WMRTET proliferating cell nuclear antigen
- rat >gi|56862|emb|CAA68261.1| (Y00047) cyclin (PCNA)
[Rattus norvegicus]
Length = 261
Score = 99.1 bits (243), Expect = 4e-20
Identities = 61/245 (24%), Positives = 122/245 (48%), Gaps = 11/245 (4%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E LI+EA + ++ G+++++MD S V L+ L L + F Y D +GVN+
Sbjct: 14 KVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLT 73
Query: 75 HLKKVLKRGKAKETLILRKGEENFLEISLQGTA-----TRTFKLPLIDVEEIEVDLPELP 129
+ K+LK E +I + E+N ++L A +++ L+D++ ++ +PE
Sbjct: 74 SMSKILKCA-GNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQE 132
Query: 130 FTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTL-----EDE 184
++ V + +D S + D++ ++ A GE +KL+ ++E
Sbjct: 133 YSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEE 192
Query: 185 GLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLA 244
+ IE+ E + + + YL+ K + VT+ ++P+ +EY I D G L + LA
Sbjct: 193 EAVSIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSADVPLVVEYKIADMGHLKYYLA 252
Query: 245 PRVEE 249
P++E+
Sbjct: 253 PKIED 257
>sp|P53358|PCNA_STYCL PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (CYCLIN)
>gi|1161242|gb|AAC37303.1| (L42763) proliferating cell
nuclear antigen [Styela clava]
Length = 264
Score = 98.3 bits (241), Expect = 7e-20
Identities = 58/242 (23%), Positives = 119/242 (48%), Gaps = 10/242 (4%)
Query: 18 ETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMDHLK 77
E ++ EA++ T GIS++AMD S V L+ L L A F + D +G+NM +
Sbjct: 17 EALKDIVTEASWDCTSSGISLQAMDSSHVSLVQLTLRADGFENFRCDRNLAMGINMTSMA 76
Query: 78 KVLKRGKAKETLILR-KGEENFLEI---SLQGTATRTFKLPLIDVEEIEVDLPELPFTAK 133
K++K + + LR + + LE+ S +G +++ L+D++ ++ +PE ++
Sbjct: 77 KIMKCAGNDDIITLRAEDNADMLELIFESSKGDKYSQYEMKLMDLDCEQLGIPEQDYSCC 136
Query: 134 VVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKL------TLEDEGLL 187
V + +D S + + + ++ A+G+ ++KL +++E +
Sbjct: 137 VTLPSQEFGRICRDLSQIGECVVITCTKDGVQFSAKGDLGAGKIKLKQNTGSDIKEEEQV 196
Query: 188 DIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLAPRV 247
+E+ E + + I YL+ K + V + N +P+ +EY + D G + + LAP++
Sbjct: 197 TVEISEPVQLTFAIKYLNLFAKASPLSPSVCLSMSNNVPLVVEYKVADMGHIKYFLAPKI 256
Query: 248 EE 249
E+
Sbjct: 257 ED 258
>sp|O02115|PCNA_CAEEL PROBABLE PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (CYCLIN)
>gi|7508883|pir||T28761 hypothetical protein W03D2.4 -
Caenorhabditis elegans >gi|1947162|gb|AAC48257.1|
(AF000298) strong similarity to proliferating cell
nuclear antigens (cyclins) [Caenorhabditis elegans]
Length = 263
Score = 97.9 bits (240), Expect = 1e-19
Identities = 62/258 (24%), Positives = 120/258 (46%), Gaps = 12/258 (4%)
Query: 3 FEIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYE 62
FE A +++E+ L+ +A F +E +S++AMD S V L+ L L +F Y
Sbjct: 2 FEAKLANAGLLKKIVESIKDLVTDAPFDCSETAMSLQAMDSSHVALVSLKLEVGLFDTYR 61
Query: 63 VDGEETIGVNMDHLKKVLKRGKAKETLILRKGEEN------FLEISLQGTATRTFKLPLI 116
D +G+++ ++ K LK +T +L K EEN F + T+ + ++
Sbjct: 62 CDRTINLGLSLANMSKALKCANNDDTCML-KYEENEGDSIIFTFADPKRDKTQDVTVKMM 120
Query: 117 DVEEIEVDLPELPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVE 176
D++ + +P+ + + ++ KD S SDS+ A + +G+
Sbjct: 121 DIDSEHLGIPDQDYAVVCEMPAGEFQKTCKDLSTFSDSLNITATKAGIVFTGKGDIGSSV 180
Query: 177 VKL-----TLEDEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEY 231
V T ++ + +EV++ + I Y++ K +D V + N++P+ +EY
Sbjct: 181 VTYSPSSNTDDETEAVTLEVKDPVNVNFSIKYMNQFTKATALSDRVRLSLCNDVPVVVEY 240
Query: 232 YIRDEGRLIFLLAPRVEE 249
I + G L F LAP++++
Sbjct: 241 PIEENGYLRFYLAPKIDD 258
>gb|AAF53835.1| (AE003663) CG10262 gene product [Drosophila melanogaster]
Length = 255
Score = 97.9 bits (240), Expect = 1e-19
Identities = 55/239 (23%), Positives = 117/239 (48%), Gaps = 4/239 (1%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
++++ +I + +E G+ +++MD S V L+ L+L + F K+ D ++G+++
Sbjct: 14 KIVDALKEIIAQGTLDCSENGLELQSMDNSHVSLVALSLASDCFEKFHCDRNVSLGLDLK 73
Query: 75 HLKKVLKRGKAKETLILR---KGEENFLEISLQGTA-TRTFKLPLIDVEEIEVDLPELPF 130
L KVLK + + + ++ + E+ L G T ++L L+++++ +++P+ +
Sbjct: 74 SLGKVLKCANSDDAVTIKAVDRPEKITLSFESDGKERTADYELKLLNLDQDHMEIPKKDY 133
Query: 131 TAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTLEDEGLLDIE 190
T + + +D S+ +S+ A+G+ ++L+ + IE
Sbjct: 134 TCFIQLPSSEFARICRDMSMFDESLTIACSSKGIRFLAKGDLGTANIQLSAGTAMDVSIE 193
Query: 191 VQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLAPRVEE 249
VQE ++ YL+ K AD V + +E P+ +EY I D G + + LAP+V +
Sbjct: 194 VQEPVTQSFAGRYLNTFTKATPLADRVKLYLSDERPLLVEYPIEDYGHIRYYLAPKVND 252
>sp|Q03392|PCNA_SCHPO PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) >gi|319908|pir||WMZPET
proliferating cell nuclear antigen [validated] - fission
yeast (Schizosaccharomyces pombe)
>gi|7493184|pir||T39573 proliferating cell nuclear
antigen - fission yeast (Schizosaccharomyces pombe)
>gi|5003|emb|CAA38636.1| (X54857) proliferating cell
nuclear antigen [Schizosaccharomyces pombe]
>gi|4481955|emb|CAB38513.1| (AL035637) proliferating
cell nuclear antigen [Schizosaccharomyces pombe]
Length = 260
Score = 96.3 bits (236), Expect = 3e-19
Identities = 63/257 (24%), Positives = 124/257 (47%), Gaps = 14/257 (5%)
Query: 4 EIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEV 63
E F+ A +L++ L+ +A F + GIS++AMD S V L+ + + + F Y
Sbjct: 3 EARFQQAALLKKLLDAIKELVTDANFDCNDNGISLQAMDSSHVALVSMLIKSDGFEPYRC 62
Query: 64 DGEETIGVNMDHLKKVLKRGKAKETLILRKGEE-----NFLEISLQGTATRTFKLPLIDV 118
D +G+N++ L KVL R E L+ K E+ N + S + + + L+D+
Sbjct: 63 DRNIALGINLNALSKVL-RCAQNEDLVTLKAEDTPEVLNLVFESEKNDRISDYDVKLMDI 121
Query: 119 EEIEVDLPELPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGE------T 172
++ + +P++ + A + + + +D +SDS+ A + +G+ T
Sbjct: 122 DQEHLGIPDIEYDATITMPAAEFQRITRDLLTLSDSVTINASKEGVRFSCKGDIGNGSTT 181
Query: 173 QEVEVKLTLEDEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYY 232
+ L+ +D+ ++I + + + + YL+ K A VT+ N++P+ +EY
Sbjct: 182 LKQHTDLSDQDQS-IEISLTQAVTLTFSLKYLAQFTKATPLATRVTLSMSNDVPLLVEYK 240
Query: 233 IRDEGRLIFLLAPRVEE 249
+ + G L F LAP++ E
Sbjct: 241 M-ESGFLRFYLAPKIGE 256
>gb|AAB31034.1| proliferating cell nuclear antigen, PCNA [Saccharomyces cerevisiae,
pol30-33, Peptide Mutant, 257 aa]
Length = 257
Score = 95.6 bits (234), Expect = 5e-19
Identities = 65/254 (25%), Positives = 127/254 (49%), Gaps = 9/254 (3%)
Query: 4 EIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEV 63
E FE A F ++I+ + F+ E+GI +A+D SRV+L+ L + F +Y
Sbjct: 3 EAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYRC 62
Query: 64 DGEETIGVNMDHLKKVLKRGKAKETL-ILRKGEENFLEISLQGT---ATRTFKLPLIDVE 119
D T+G+++ L K+L+ G +TL ++ + + + + T + L L+D++
Sbjct: 63 DHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMDID 122
Query: 120 EIEVDLPELPFTAKVVILGDVIKEAVKDASLVSDSMK-FIAKENEFTMRAEGETQEVEVK 178
+ + EL + + + + + V+D+S +SDS+ I KE +F + + V +K
Sbjct: 123 ADFLKIEELQYDSTLSLPSSEFSKIVRDSSQLSDSINIMITKEIKFVADGDIGSGSVIIK 182
Query: 179 LTLE---DEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRD 235
++ E + +E+ + +G YL D++KG +D V I+ +E P ++ ++
Sbjct: 183 PFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLK- 241
Query: 236 EGRLIFLLAPRVEE 249
G L F LAP+ +
Sbjct: 242 SGFLQFFLAPKFND 255
>emb|CAC17700.1| (AJ301669) putative proliferating cell nuclear antigen [Coturnix
japonica]
Length = 262
Score = 95.2 bits (233), Expect = 6e-19
Identities = 61/245 (24%), Positives = 119/245 (47%), Gaps = 11/245 (4%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E LI EA + + GIS+++MD S V L+ L L + F Y D +GVN++
Sbjct: 14 RVLEALKDLITEACWDLGSGGISLQSMDSSHVSLVQLTLRSEGFDTYRCDRNIAMGVNLN 73
Query: 75 HLKKVLKRGKAKETLILRKGEENFLEISL-----QGTATRTFKLPLIDVEEIEVDLPELP 129
+ K+LK E +I + E+N ++L +++ L+D++ ++ +PE
Sbjct: 74 SMSKILKCA-GNEDIITLRAEDNADTLALVFETPNQEKVSDYEMKLMDLDVEQLGIPEQE 132
Query: 130 FTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTL-----EDE 184
++ V + +D S + D++ ++ A GE +KL+ ++E
Sbjct: 133 YSCVVKMPSAEFARICRDLSHIGDAVVISCAKDGVKFSANGELGNGNIKLSQTSNVDKEE 192
Query: 185 GLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLA 244
+ IE+ E + + + YL+ K + VT+ ++P+ +EY I D G + LA
Sbjct: 193 EAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSADVPLVVEYKIADMGHXKYYLA 252
Query: 245 PRVEE 249
P++E+
Sbjct: 253 PKIED 257
>gi|9632127 similar to Periwinkle PCNA, corresponds to GenBank Accession Number
X55052 [Paramecium bursaria Chlorella virus 1]
>gi|3334295|sp|O41056|PCN2_CHVP1 PROLIFERATING CELL
NUCLEAR ANTIGEN HOMOLOG A574L >gi|7461876|pir||T18076
proliferating cell nuclear antigen homolog A574L -
Chlorella virus PBCV-1 >gi|2447069|gb|AAC96927.1|
(U42580) similar to Periwinkle PCNA, corresponds to
GenBank Accession Number X55052 [Paramecium bursaria
Chlorella virus 1]
Length = 264
Score = 94.8 bits (232), Expect = 8e-19
Identities = 63/250 (25%), Positives = 124/250 (49%), Gaps = 11/250 (4%)
Query: 3 FEIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYE 62
F IV + A+ +L + L+D A T EG+S+++MD S V L++L + S F Y
Sbjct: 16 FTIVSDAAETIKKLFVVFNDLVDIANLSFTNEGLSVQSMDTSHVSLVNLKIGKSYFKDYS 75
Query: 63 VDGEETIGVNMDHLKKVLK-RGKAKETLILRKGEENFLEISLQGTATRTFKLPLIDVEEI 121
+ E T+G+ + + ++L G + T+ + L + + + FK+ ID+E
Sbjct: 76 IAQEATVGIKISNFVRILDCVGNDEITISFTYDNPDELIVKSEYS---DFKMKTIDIETE 132
Query: 122 EVDLPELPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTL 181
E+++PE+ + ++I++ +K+ + D++K +++ M+ GE EV+ L +
Sbjct: 133 EMEIPEMDIDVLIDADSNIIQKYLKNMAGFGDTVKIYTQDDVVHMKTAGEIGEVD--LQI 190
Query: 182 EDEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYI--RDEGRL 239
D+ +E++ + YL K G + V IK ++ P EY + ++
Sbjct: 191 HDQ---RVEIKGRLTCEFATRYLMTFAKAAGISKRVVIKLLDDQPGIFEYVFDAESDSKI 247
Query: 240 IFLLAPRVEE 249
F LAP+V++
Sbjct: 248 SFFLAPKVKD 257
>sp|P24314|PCNA_CATRO PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (CYCLIN)
>gi|100169|pir||S15434 proliferating cell nuclear
antigen - Madagascar periwinkle
>gi|18172|emb|CAA38893.1| (X55052) proliferating cell
nuclear antigen [Catharanthus roseus]
Length = 268
Score = 94.4 bits (231), Expect = 1e-18
Identities = 64/245 (26%), Positives = 122/245 (49%), Gaps = 11/245 (4%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E+ L+ +A F + G S++AMD S V L+ L L + F Y D ++G+N++
Sbjct: 14 KVLESLKDLVTDANFDCSASGFSLQAMDSSHVALVALLLRSEGFEHYRCDRNPSMGMNLN 73
Query: 75 HLKKVLKRGKAKETLILRKGEEN----FLEISLQGTATRTFKLPLIDVEEIEVDLPELPF 130
++ K+LK + + L+ + + F+ S F++ L+D++ + +PE +
Sbjct: 74 NMAKMLKCAGNDDIITLKADDGSDTVTFMFESPTQDKISDFEMKLMDIDSEHLGIPEAEY 133
Query: 131 TAKVVILGDVIKEAVKDASLVSDSMKF-IAKEN-EFTMRAEGETQEV----EVKLTLEDE 184
A V + KD S + D++ + KE +F+ R + T + + DE
Sbjct: 134 HAIVRMPSAEFARICKDLSSIGDTVVISVTKEGVKFSTRGDIGTANIVCRQNTTVDKPDE 193
Query: 185 GLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLA 244
+ IE+ E + + YL+ K ++ VTI +E+P+ +EY I + G + F LA
Sbjct: 194 ATI-IEMNEPVSLTFALRYLNSFTKATPLSNNVTISLSSELPVVVEYKIAEMGYIRFYLA 252
Query: 245 PRVEE 249
P++EE
Sbjct: 253 PKIEE 257
>sp|Q00265|PCN2_DAUCA PROLIFERATING CELL NUCLEAR ANTIGEN, LARGE FORM (PCNA) (CYCLIN)
>gi|478596|pir||S20591 proliferating cell nuclear
antigen large form - carrot
Length = 365
Score = 94.0 bits (230), Expect = 1e-18
Identities = 62/245 (25%), Positives = 124/245 (50%), Gaps = 11/245 (4%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E+ L+++A F + G S++AMD S V L+ + L + F Y D ++G+N+
Sbjct: 14 KVLESIKDLVNDANFDCSASGFSLQAMDSSHVALVAVLLRSEGFEHYRCDRNISMGMNLG 73
Query: 75 HLKKVLKRGKAKETLILRKGEEN-----FLEISLQGTATRTFKLPLIDVEEIEVDLPELP 129
++ K+L R + ++ K +++ F+ S F++ L+D++ + +PE
Sbjct: 74 NMAKML-RCAGNDDIVTMKADDDGDVITFMFESPTQDKISDFEMKLMDIDSEHLGIPESE 132
Query: 130 FTAKVVILGDVIKEAVKDASLVSDSMKF-IAKEN-EFTMRAEGETQEVEVKLTL---EDE 184
+ A V + KD S + D++ + KE +F+ R + T + + + E
Sbjct: 133 YEAIVRMPSAEFARICKDLSTIGDTVVISVTKEGVKFSTRGDIGTANIVCRQNTSVDKPE 192
Query: 185 GLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLA 244
IE+QE + + Y++ K A++VTI +E+P+ +EY I + G + + LA
Sbjct: 193 DATIIEMQETVSLTFALRYMNSFTKATPLANQVTISLSSELPVVVEYKIAEMGYIRYYLA 252
Query: 245 PRVEE 249
P++EE
Sbjct: 253 PKIEE 257
>gi|6319564 Proliferating cell nuclear antigen; Pol30p [Saccharomyces
cerevisiae] >gi|129701|sp|P15873|PCNA_YEAST
PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA)
>gi|319909|pir||WMBYET proliferating cell nuclear
antigen - yeast (Saccharomyces cerevisiae)
>gi|999590|pdb|1PLQ| Proliferating Cell Nuclear Antigen
(Pcna) (Synchrotron X-Ray Diffraction)
>gi|999599|pdb|1PLR| Proliferating Cell Nuclear Antigen
(Pcna) >gi|4193|emb|CAA34664.1| (X16676) proliferating
cell nuclear antigen (AA 1-258) [Saccharomyces
cerevisiae] >gi|476047|emb|CAA55594.1| (X78993)
proliferating cell nuclear antigen [Saccharomyces
cerevisiae] >gi|536356|emb|CAA85038.1| (Z35957) ORF
YBR088c [Saccharomyces cerevisiae]
Length = 258
Score = 93.6 bits (229), Expect = 2e-18
Identities = 63/255 (24%), Positives = 126/255 (48%), Gaps = 10/255 (3%)
Query: 4 EIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEV 63
E FE A F ++I+ + F+ E+GI +A+D SRV+L+ L + F +Y
Sbjct: 3 EAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYRC 62
Query: 64 DGEETIGVNMDHLKKVLKRGKAKETL-ILRKGEENFLEISLQGT---ATRTFKLPLIDVE 119
D T+G+++ L K+L+ G +TL ++ + + + + T + L L+D++
Sbjct: 63 DHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMDID 122
Query: 120 EIEVDLPELPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGE--TQEVEV 177
+ + EL + + + + + V+D S +SDS+ + + A+G+ + V +
Sbjct: 123 ADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVII 182
Query: 178 KLTLE---DEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIR 234
K ++ E + +E+ + +G YL D++KG +D V I+ +E P ++ ++
Sbjct: 183 KPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLK 242
Query: 235 DEGRLIFLLAPRVEE 249
G L F LAP+ +
Sbjct: 243 -SGFLQFFLAPKFND 256
>sp|Q43266|PCNA_MAIZE PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) >gi|1076822|pir||S52115
proliferating cell nuclear antigen (PCNA) homolog -
maize >gi|732990|emb|CAA55669.1| (X79065) proliferative
cell nuclear antigen [Zea mays]
>gi|1093954|prf||2105195A proliferating cell nuclear
antigen [Zea mays]
Length = 263
Score = 93.6 bits (229), Expect = 2e-18
Identities = 60/245 (24%), Positives = 118/245 (47%), Gaps = 11/245 (4%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E L+++A F + G S++AMD S V L+ L L A F Y D ++G+N++
Sbjct: 14 KVLEAIRELVNDANFDCSGTGFSLQAMDSSHVALVALLLRAEGFEHYRCDRNLSMGMNLN 73
Query: 75 HLKKVLKRGKAKETLILRKGEEN-----FLEISLQGTATRTFKLPLIDVEEIEVDLPELP 129
++ K+L R + +I K ++ F+ S + F++ L+D++ + +P+
Sbjct: 74 NMAKML-RCAGNDDIITIKADDGSDTVTFMFESPKQDKIADFEMKLMDIDSEHLGIPDSE 132
Query: 130 FTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEV-----KLTLEDE 184
+ A V + KD S + D++ + GE + + + E
Sbjct: 133 YQAIVRMPSSEFMRICKDLSSIGDTVVISVTKEGVKFSTSGEIGSANIVCRQNQTIDKPE 192
Query: 185 GLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLA 244
IE+QE + + Y++ K +++VTI +E+P+ +EY I + G + F LA
Sbjct: 193 EATIIEMQEPVSLTFALRYMNSFTKASSLSEQVTISLSSELPVVVEYKIAEMGYIRFYLA 252
Query: 245 PRVEE 249
P++E+
Sbjct: 253 PKIED 257
>sp|O16852|PCNA_SARCR PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (CYCLIN)
>gi|2443812|gb|AAC24238.1| (AF020427) proliferating cell
nuclear antigen [Sarcophaga crassipalpis]
Length = 260
Score = 93.6 bits (229), Expect = 2e-18
Identities = 62/257 (24%), Positives = 123/257 (47%), Gaps = 11/257 (4%)
Query: 3 FEIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYE 62
FE A ++++ L+ EA F+ +E GI ++AMD S V L L L + F K+
Sbjct: 2 FEARLINATILKKILDAIKELLHEATFECSESGIQLQAMDNSHVSLGSLTLRSDGFDKFR 61
Query: 63 VDGEETIGVNMDHLKKVLKRGKAKETLILRKGEEN-----FLEISLQGTATRTFKLPLID 117
D ++G+N+ + K+LK +T+ + K ++N F+ S +++ L++
Sbjct: 62 CDRNISMGMNLGSMAKILKCANNDDTVTV-KAQDNADTVTFMFESPNHEKVSDYEMKLMN 120
Query: 118 VEEIEVDLPELPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEV 177
+++ + +PE ++ V + +D + S+SM + A G+ V
Sbjct: 121 LDQEHLGIPETDYSCVVRMPSMEFARICRDLAQFSESMLICCTKEGVKFSASGDVGSANV 180
Query: 178 KLTL-----EDEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYY 232
KL ++E + IE+QE + YL+ K + +V + ++P+ +EY
Sbjct: 181 KLAQTSSVDKEEEAVIIEMQEPVTLTFACRYLNAFTKATPLSAQVQLSMCADVPLVVEYA 240
Query: 233 IRDEGRLIFLLAPRVEE 249
I++ G + + LAP++E+
Sbjct: 241 IKELGHIRYYLAPKIED 257
>gb|AAG24908.1|AF305075_1 (AF305075) proliferating cell nuclear antigen [Nicotiana
benthamiana]
Length = 264
Score = 93.6 bits (229), Expect = 2e-18
Identities = 64/244 (26%), Positives = 121/244 (49%), Gaps = 9/244 (3%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E+ L+++A F + G S++AMD S V L+ L L + F Y D ++G+N+
Sbjct: 14 KVLESIKELVNDANFDCSATGFSLQAMDSSHVALVALLLRSEGFEHYRCDRNISMGMNLG 73
Query: 75 HLKKVLKRGKAKETLILRKGEEN----FLEISLQGTATRTFKLPLIDVEEIEVDLPELPF 130
++ K+LK + + L+ + + F+ S F++ L+D++ + +PE +
Sbjct: 74 NMAKMLKCAGNDDIITLKADDGSDTVTFMFESPTQDKIADFEMKLMDIDSEHLGIPEAEY 133
Query: 131 TAKVVILGDVIKEAVKDASLVSDSMKF-IAKEN-EFTMRAEGETQEVEVKLTL---EDEG 185
A V + KD S + D++ + KE +F+ R + T V + + E
Sbjct: 134 HAIVRMPSAEFARICKDLSSIGDTVVISVTKEGVKFSTRGDIGTANVVCRQNTTVDKPEE 193
Query: 186 LLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLAP 245
IE+ E + + YL+ K ++ VTI +E+P+ +EY I + G + F LAP
Sbjct: 194 ATVIEMNEPVSLTFALRYLNSFTKATPLSNTVTISLSSELPVVVEYKIAEMGYIRFYLAP 253
Query: 246 RVEE 249
++EE
Sbjct: 254 KIEE 257
>sp|P17917|PCNA_DROME PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (CYCLIN)
(MUTAGEN-SENSITIVE 209 PROTEIN) >gi|85117|pir||A34752
proliferating cell nuclear antigen - fruit fly
(Drosophila melanogaster) >gi|158038|gb|AAA28746.1|
(M33950) proliferating cell nuclear antigen [Drosophila
melanogaster] >gi|7302405|gb|AAF57493.1| (AE003792)
mus209 gene product [Drosophila melanogaster]
Length = 260
Score = 93.2 bits (228), Expect = 2e-18
Identities = 58/257 (22%), Positives = 125/257 (48%), Gaps = 11/257 (4%)
Query: 3 FEIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYE 62
FE A ++++ L++EA F ++ GI ++AMD S V L+ L L + F K+
Sbjct: 2 FEARLGQATILKKILDAIKDLLNEATFDCSDSGIQLQAMDNSHVSLVSLTLRSDGFDKFR 61
Query: 63 VDGEETIGVNMDHLKKVLKRGKAKETLILRKGEENFLEISLQGTATR-----TFKLPLID 117
D ++G+N+ + K+LK ++ + + K ++N +++ + +++ L++
Sbjct: 62 CDRNLSMGMNLGSMAKILKCANNEDNVTM-KAQDNADTVTIMFESANQEKVSDYEMKLMN 120
Query: 118 VEEIEVDLPELPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEV 177
+++ + +PE F+ V + +D + S+S+ + A G+ +
Sbjct: 121 LDQEHLGIPETDFSCVVRMPAMEFARICRDLAQFSESVVICCTKEGVKFSASGDVGTANI 180
Query: 178 KLTL-----EDEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYY 232
KL ++E + IE+QE + YL+ K + +V + ++P+ +EY
Sbjct: 181 KLAQTGSVDKEEEAVIIEMQEPVTLTFACRYLNAFTKATPLSTQVQLSMCADVPLVVEYA 240
Query: 233 IRDEGRLIFLLAPRVEE 249
I+D G + + LAP++E+
Sbjct: 241 IKDLGHIRYYLAPKIED 257
>sp|Q43124|PCNA_BRANA PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) >gi|7440029|pir||T09523
proliferating cell nuclear antigen PCNA - rape
>gi|408232|gb|AAB27811.1| (S64617) PCNA=proliferating
cell nuclear antigen [Brassica napus=oilseed rape, cv.
Westar, apical meristem, Peptide, 263 aa]
Length = 263
Score = 92.8 bits (227), Expect = 3e-18
Identities = 55/244 (22%), Positives = 118/244 (47%), Gaps = 9/244 (3%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E+ L+++A F + G S++AMD S V L+ L L + F Y D ++G+N+
Sbjct: 14 KVLESIKDLVNDANFDCSTTGFSLQAMDSSHVALVSLLLRSEGFEHYRCDRNLSMGMNLG 73
Query: 75 HLKKVLKRGKAKETLILRKGEEN----FLEISLQGTATRTFKLPLIDVEEIEVDLPELPF 130
++ K+LK + + ++ + F+ S + F++ L+D++ + +P+ +
Sbjct: 74 NMSKMLKCAGNDDIITIKADDGGDTVTFMFESPKQDKIADFEMKLMDIDSEHLGIPDAEY 133
Query: 131 TAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTL-----EDEG 185
+ V + + KD S + D++ + G+ + L + E
Sbjct: 134 HSIVRMPSNEFSRICKDLSTIGDTVVISVTKEGVKFSTAGDIGTANIVLRQNTTVDKPED 193
Query: 186 LLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLAP 245
+ IE+ E ++ + Y++ K +D VTI +E+P+ +EY + + G + + LAP
Sbjct: 194 AIVIEMNEPVSLSFALRYMNSFTKATPLSDTVTISLSSELPVVVEYKVAEMGYIRYYLAP 253
Query: 246 RVEE 249
++EE
Sbjct: 254 KIEE 257
>gb|AAD19905.1| (AF104412) proliferating cell nuclear antigen II [Nicotiana
tabacum]
Length = 264
Score = 92.8 bits (227), Expect = 3e-18
Identities = 63/244 (25%), Positives = 122/244 (49%), Gaps = 9/244 (3%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E+ L+++A F + G S++AMD S V L+ L L + F Y D ++G+N+
Sbjct: 14 KVLESIKDLVNDANFDCSATGFSLQAMDSSHVALVALLLRSEGFEHYRCDRNISMGMNLG 73
Query: 75 HLKKVLKRGKAKETLILRKGEEN----FLEISLQGTATRTFKLPLIDVEEIEVDLPELPF 130
++ K+LK + + L+ + + F+ S F++ L+D++ + +PE +
Sbjct: 74 NMAKMLKCAGNDDIITLKADDGSDTVTFMFESPTQDKIADFEMRLMDIDSEHLGIPEAEY 133
Query: 131 TAKVVILGDVIKEAVKDASLVSDSMKF-IAKEN-EFTMRAEGETQEVEVKLTL---EDEG 185
A +++ KD S + D++ + KE +F+ R + T V + + E
Sbjct: 134 HAILIMPSAEFARICKDLSSIGDTVVISVTKEGVKFSTRGDIGTANVVCRQNTTVDKPEE 193
Query: 186 LLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLAP 245
IE+ E + + YL+ K ++ VTI +E+P+ +EY I + G + F LAP
Sbjct: 194 ATVIEMPEPVSLTFALRYLNSFTKATPLSNTVTISLSSEIPVVVEYKIAEMGYIRFYLAP 253
Query: 246 RVEE 249
++EE
Sbjct: 254 KIEE 257
>sp|O82797|PCNA_TOBAC PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA)
>gi|3366661|gb|AAC27992.1| (AF038875) proliferating cell
nuclear antigen [Nicotiana tabacum]
>gi|3514105|gb|AAC34126.1| (AF085197) proliferating cell
nuclear antigen [Nicotiana tabacum]
>gi|4586306|dbj|BAA76349.1| (AB025029) proliferating
cell nuclear antigen [Nicotiana tabacum]
Length = 264
Score = 92.4 bits (226), Expect = 4e-18
Identities = 63/244 (25%), Positives = 121/244 (48%), Gaps = 9/244 (3%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E+ L+++A F + G S++AMD S V L+ L L + F Y D ++G+N+
Sbjct: 14 KVLESIKDLVNDANFDCSATGFSLQAMDSSHVALVALLLRSEGFEHYRCDRNISMGMNLA 73
Query: 75 HLKKVLKRGKAKETLILRKGEEN----FLEISLQGTATRTFKLPLIDVEEIEVDLPELPF 130
++ K+LK + + L+ + + F+ S F++ L+D++ + +PE +
Sbjct: 74 NMAKMLKCAGNDDIITLKADDGSDTVTFMFESPTQDKIADFEMKLMDIDSEHLGIPEAEY 133
Query: 131 TAKVVILGDVIKEAVKDASLVSDSMKF-IAKEN-EFTMRAEGETQEVEVKLTL---EDEG 185
A V + KD S + D++ + KE +F+ R + T + + + E
Sbjct: 134 HAIVRMPSAEFSRICKDLSSIGDTVVISVTKEGVKFSTRGDIGTANIVCRQNTTVDKPEE 193
Query: 186 LLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLAP 245
IE+ E + + YL+ K ++ VTI +E+P+ +EY I + G + F LAP
Sbjct: 194 ATVIEMNEPVSLTFALRYLNSFTKATPLSNTVTISLSSELPVVVEYKIAEMGYIRFYLAP 253
Query: 246 RVEE 249
++EE
Sbjct: 254 KIEE 257
>dbj|BAA33151.1| (AB008186) proliferating cell nuclear antigen [Pisum sativum]
>gi|3821259|emb|CAA77062.1| (Y18135) PCNA protein
[Nicotiana tabacum] >gi|4379382|emb|CAA76392.1| (Y16796)
proliferating cell nuclear antigen [Pisum sativum]
Length = 266
Score = 92.4 bits (226), Expect = 4e-18
Identities = 59/244 (24%), Positives = 117/244 (47%), Gaps = 9/244 (3%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E+ L+++A F + G S++AMD S V L+ L L + F Y D ++G+N++
Sbjct: 14 KVLESIKELVNDANFDCSSTGFSLQAMDSSHVALVALLLRSEGFEHYRCDRNLSMGMNLN 73
Query: 75 HLKKVLKRGKAKETLILRKGEEN----FLEISLQGTATRTFKLPLIDVEEIEVDLPELPF 130
++ K+LK + + ++ + + F+ S F++ L+D++ + +PE +
Sbjct: 74 NMAKMLKCAGNDDIITIKADDGSDTVTFMFESPTQDKISDFEMKLMDIDSEHLGIPEAEY 133
Query: 131 TAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEV----KLTLE-DEG 185
A V + KD S + D++ + +G+ + T++ E
Sbjct: 134 HAIVRMPSAEFARICKDLSSIGDTVVIAVSKEGVKFSTKGDIGSANIVCRQNTTVDKPEE 193
Query: 186 LLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLAP 245
IE+ E + + Y++ K + VTI NE+P+ +EY I + G + F LAP
Sbjct: 194 ATVIEMNEPVALQFALRYMNSFTKATPLSSSVTISLSNELPVVVEYKIAEMGYVRFYLAP 253
Query: 246 RVEE 249
++EE
Sbjct: 254 KIEE 257
>emb|CAA10108.1| (AJ012662) proliferating cell nuclear antigen [Nicotiana tabacum]
Length = 264
Score = 92.4 bits (226), Expect = 4e-18
Identities = 64/244 (26%), Positives = 120/244 (48%), Gaps = 9/244 (3%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E+ L+++A F + G S++AMD S V L+ L L + F Y D ++G+N+
Sbjct: 14 KVLESIKDLVNDANFDCSATGFSLQAMDSSHVALVALLLRSEGFEHYRCDRNISMGMNLG 73
Query: 75 HLKKVLKRGKAKETLILRKGEEN----FLEISLQGTATRTFKLPLIDVEEIEVDLPELPF 130
++ K+LK + + L+ + + F+ S F++ L+D++ + +PE +
Sbjct: 74 NMAKMLKCAGNDDIITLKADDGSDTVTFMFESPTQDKIADFEMKLMDIDSEHLGIPEAEY 133
Query: 131 TAKVVILGDVIKEAVKDASLVSDSMKF-IAKEN-EFTMRAEGETQEVEVKLTL---EDEG 185
A V + KD S + D + + KE +F+ R + T V + + E
Sbjct: 134 HAIVRMPSAEFARICKDLSSIGDQVVISVTKEGVKFSTRGDIGTANVVCRQNTTVDKPEE 193
Query: 186 LLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLAP 245
IE+ E + + YL+ K ++ VTI +E+P+ +EY I + G + F LAP
Sbjct: 194 ATVIEMNEPVSLTFALRYLNSFTKATPLSNTVTISLSSELPVVVEYKIAEMGYIRFYLAP 253
Query: 246 RVEE 249
++EE
Sbjct: 254 KIEE 257
>gb|AAF79566.1|AC022464_24 (AC022464) F22G5.29 [Arabidopsis thaliana]
Length = 263
Score = 92.4 bits (226), Expect = 4e-18
Identities = 55/244 (22%), Positives = 118/244 (47%), Gaps = 9/244 (3%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E+ L+++A F + G S++AMD S V L+ L L + F Y D ++G+N+
Sbjct: 14 KVLESIKDLVNDANFDCSSTGFSLQAMDSSHVALVSLLLRSEGFEHYRCDRNLSMGMNLG 73
Query: 75 HLKKVLKRGKAKETLILRKGEEN----FLEISLQGTATRTFKLPLIDVEEIEVDLPELPF 130
++ K+LK + + ++ + F+ S F++ L+D++ + +P+ +
Sbjct: 74 NMSKMLKCAGNDDIITIKADDGGDTVTFMFESPTQDKIADFEMKLMDIDSEHLGIPDAEY 133
Query: 131 TAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTL-----EDEG 185
+ V + + KD S + D++ + G+ + L + E
Sbjct: 134 HSIVRMPSNEFSRICKDLSSIGDTVVISVTKEGVKFSTAGDIGTANIVLRQNTTVDKPED 193
Query: 186 LLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLAP 245
+ IE++E ++ + Y++ K +D VTI +E+P+ +EY + + G + + LAP
Sbjct: 194 AIVIEMKEPVSLSFALRYMNSFTKATPLSDTVTISLSSELPVVVEYKVAEMGYIRYYLAP 253
Query: 246 RVEE 249
++EE
Sbjct: 254 KIEE 257
>sp|P17070|PCNA_ORYSA PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (CYCLIN)
>gi|100698|pir||S14415 proliferating cell nuclear
antigen - rice >gi|20284|emb|CAA37979.1| (X54046)
proliferating cell nuclear antigen [Oryza sativa]
Length = 263
Score = 92.1 bits (225), Expect = 6e-18
Identities = 60/245 (24%), Positives = 116/245 (46%), Gaps = 11/245 (4%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E L+ +A F + G S++AMD S V L+ L L + F Y D ++G+N++
Sbjct: 14 KVLEAIRELVTDANFDCSGTGFSLQAMDSSHVALVALLLRSEGFEHYRCDRNLSMGMNLN 73
Query: 75 HLKKVLKRGKAKETLILRKGEEN-----FLEISLQGTATRTFKLPLIDVEEIEVDLPELP 129
++ K+L R + +I K ++ F+ S F++ L+D++ + +P+
Sbjct: 74 NMAKML-RCAGNDDIITIKADDGSDTVTFMFESPNQDKIADFEMKLMDIDSEHLGIPDSE 132
Query: 130 FTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEV-----KLTLEDE 184
+ A V + KD S + D++ + G+ + K + E
Sbjct: 133 YQAIVRMPSSEFSRICKDLSSIGDTVIISVTKEGVKFSTAGDIGTANIVCRQNKTVDKPE 192
Query: 185 GLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLA 244
IE+QE + + Y++ K +++VTI +E+P+ +EY I + G + F LA
Sbjct: 193 DATIIEMQEPVSLTFALRYMNSFTKASPLSEQVTISLSSELPVVVEYKIAEMGYIRFYLA 252
Query: 245 PRVEE 249
P++EE
Sbjct: 253 PKIEE 257
>sp|O01377|PCNA_BOMMO PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (CYCLIN)
>gi|7440016|pir||JC5890 proliferating cell nuclear
antigen - silkworm >gi|1944021|dbj|BAA19522.1|
(AB002264) PCNA [Bombyx mori]
Length = 260
Score = 92.1 bits (225), Expect = 6e-18
Identities = 60/245 (24%), Positives = 115/245 (46%), Gaps = 11/245 (4%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E L+ +A F + GI ++AMD S V L+ L L A F KY D ++G+N+
Sbjct: 14 KVLEAIKDLLTQATFDCDDNGIQLQAMDNSHVSLVSLTLRADGFDKYRCDRNISMGMNLG 73
Query: 75 HLKKVLKRGKAKETLILRKGEEN-----FLEISLQGTATRTFKLPLIDVEEIEVDLPELP 129
+ K+L K+T + K ++N F+ S +++ L++++ + +PE
Sbjct: 74 SMSKILIFAGDKDTATI-KAQDNADNVTFVFESPNQEKVSDYEMKLMNLDLEHLGIPETE 132
Query: 130 FTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTL-----EDE 184
++ + + +D S +SM + A G+ VKL ++E
Sbjct: 133 YSCTIRMPSSEFARICRDLSQFGESMVISCTKEGVKFSATGDIGSANVKLAQTASIDKEE 192
Query: 185 GLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLA 244
+ IE++E + YL+ K + +V + ++P+ +EY I D G + + LA
Sbjct: 193 EAVVIEMEEPVTLTFACQYLNYFTKATSLSPQVQLSMSADVPLVVEYRIPDIGHIRYYLA 252
Query: 245 PRVEE 249
P++EE
Sbjct: 253 PKIEE 257
>gb|AAD10528.1| (U87949) proliferating cell nuclear antigen [Zea mays]
Length = 263
Score = 92.1 bits (225), Expect = 6e-18
Identities = 60/245 (24%), Positives = 117/245 (47%), Gaps = 11/245 (4%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E L+ +A F + G S++AMD S V L+ L L A F Y D ++G+N++
Sbjct: 14 KVLEAIRELVTDANFDCSGTGFSLQAMDSSHVALVALLLRAEGFEHYRCDRNLSMGMNLN 73
Query: 75 HLKKVLKRGKAKETLILRKGEEN-----FLEISLQGTATRTFKLPLIDVEEIEVDLPELP 129
++ K+L R E +I K ++ F+ S + F++ L+D++ + +P+
Sbjct: 74 NMAKML-RCAGNEDIITIKADDGSDTVTFMFESPKQDKIADFEMKLMDIDSEHLGIPDSE 132
Query: 130 FTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEV-----KLTLEDE 184
+ A V + KD S + D++ + GE + + + E
Sbjct: 133 YQAIVRMPSAEFMRICKDLSSIGDTVVISVTKEGVKFSTSGEIGSANIVCRQNQTIDKPE 192
Query: 185 GLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLA 244
IE+QE + + Y++ K +++VTI +E+P+ +EY I + G + F LA
Sbjct: 193 EATIIEMQEPVSLTFALRYMNSFTKASSLSEQVTISLSSELPVVVEYKIAEMGYIRFYLA 252
Query: 245 PRVEE 249
P++++
Sbjct: 253 PKIDD 257
>dbj|BAA94512.1| (AB041506) proliferating cell nuclear antigen [Populus nigra]
Length = 264
Score = 91.3 bits (223), Expect = 1e-17
Identities = 61/245 (24%), Positives = 122/245 (48%), Gaps = 11/245 (4%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E+ L+++A F + G S+++MD S V L+ L L + F Y D ++G+N+
Sbjct: 14 KVLESIKDLVNDANFDFSSSGFSLQSMDSSHVALVALLLKSEGFEHYRCDRNTSMGMNLG 73
Query: 75 HLKKVLKRGKAKETLILRKGEE-----NFLEISLQGTATRTFKLPLIDVEEIEVDLPELP 129
++ K+LK + +I KG++ F+ S F++ L+D++ + +PE
Sbjct: 74 NMSKMLKCA-GNDDIITIKGDDGSDTVTFMFESPTQDKIADFEMKLMDIDSEHLGIPEAE 132
Query: 130 FTAKVVILGDVIKEAVKDASLVSDSMKF-IAKEN-EFTMRAEGETQEVEVKLTL---EDE 184
+ A V + KD + + D++ + KE +F+ R + T + ++ + E
Sbjct: 133 YHAIVKMPSAEFARICKDLASIGDTVVISVTKEGVKFSTRGDIGTANIVLRQNTTVDKPE 192
Query: 185 GLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLA 244
IE+ E + + Y++ K ++ VTI ++P+ +EY I + G + F LA
Sbjct: 193 DATVIEMNEPVSMTFALRYMNSFTKATPLSNTVTISMSPDLPVVVEYKIAEMGYVRFYLA 252
Query: 245 PRVEE 249
P++EE
Sbjct: 253 PKMEE 257
>gb|AAF40018.1|AF083220_1 (AF083220) proliferating cellular nuclear antigen [Arabidopsis
thaliana]
Length = 263
Score = 90.9 bits (222), Expect = 1e-17
Identities = 55/244 (22%), Positives = 117/244 (47%), Gaps = 9/244 (3%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E+ L+++A F + G S++AMD S V L L L + F Y D ++G+N+
Sbjct: 14 KVLESIKDLVNDANFDCSSTGFSLQAMDSSHVALASLLLRSEGFEHYRCDRNLSMGMNLG 73
Query: 75 HLKKVLKRGKAKETLILRKGEEN----FLEISLQGTATRTFKLPLIDVEEIEVDLPELPF 130
++ K+LK + + ++ + F+ S F++ L+D++ + +P+ +
Sbjct: 74 NMSKMLKCAGNDDIITIKADDGGDTVTFMFESPTQDKIADFEMKLMDIDSEHLGIPDAEY 133
Query: 131 TAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTL-----EDEG 185
+ V + + KD S + D++ + G+ + L + E
Sbjct: 134 HSIVRMPSNEFSRICKDLSSIGDTVVISVTKEGVKFSTAGDIGTANIVLRQNTTVDKPED 193
Query: 186 LLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLAP 245
+ IE++E ++ + Y++ K +D VTI +E+P+ +EY + + G + + LAP
Sbjct: 194 AIVIEMKEPVSLSFALRYMNSFTKATPLSDTVTISLSSELPVVVEYKVAEMGYIRYYLAP 253
Query: 246 RVEE 249
++EE
Sbjct: 254 KIEE 257
>emb|CAB56779.1| (X62976) proliferating cell-nuclear antigen [Daucus carota]
Length = 367
Score = 90.5 bits (221), Expect = 2e-17
Identities = 61/247 (24%), Positives = 126/247 (50%), Gaps = 13/247 (5%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E+ L+++A F + G S++AMD S V L+ + L + F Y D ++G+N+
Sbjct: 14 KVLESIKDLVNDANFDCSASGFSLQAMDSSHVALVAVLLRSEGFEHYRCDRNISMGMNLG 73
Query: 75 HLKKVLKRGKAKETLILRKGEEN-----FLEISLQGTATRTFKLPLIDVEEIEVDLPELP 129
++ K+L R + ++ K +++ F+ S F++ L+D++ + +PE
Sbjct: 74 NMAKML-RCAGNDDIVTMKADDDGDVITFMFESPTQDKISDFEMKLMDIDSEHLGIPESE 132
Query: 130 FTAKVVILGDVIKEA--VKDASLVSDSMKF-IAKEN-EFTMRAEGETQEVEVKLTL---E 182
+ + ++ + A KD S + D++ + KE +F+ R + T + + +
Sbjct: 133 YEYEAIVRMPSAEFARICKDLSTIGDTVVISVTKEGVKFSTRGDIGTANIVCRQNTSVDK 192
Query: 183 DEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFL 242
E IE+QE + + Y++ K A++VTI +E+P+ +EY I + G + +
Sbjct: 193 PEDATIIEMQETVSLTFALRYMNSFTKATPLANQVTISLSSELPVVVEYKIAEMGYIRYY 252
Query: 243 LAPRVEE 249
LAP++EE
Sbjct: 253 LAPKIEE 259
>sp|Q9ZW35|PCNA_ARATH PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA)
>gi|3980379|gb|AAC95182.1| (AC004561) putative
proliferating cell nuclear antigen, PCNA [Arabidopsis
thaliana]
Length = 264
Score = 89.7 bits (219), Expect = 3e-17
Identities = 54/244 (22%), Positives = 116/244 (47%), Gaps = 9/244 (3%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E L+++A F + G S++AMD S V L+ L L + F Y D ++G+N+
Sbjct: 14 KVLEAVKDLVNDANFDCSTTGFSLQAMDSSHVALVSLLLRSEGFEHYRCDRNLSMGMNLG 73
Query: 75 HLKKVLKRGKAKETLILRKGEEN----FLEISLQGTATRTFKLPLIDVEEIEVDLPELPF 130
++ K+LK + + ++ + + F+ S F++ L+D++ + +P+ +
Sbjct: 74 NMSKMLKCAGNDDIITIKADDGSDTVTFMFESPTQDKIADFEMKLMDIDSEHLGIPDAEY 133
Query: 131 TAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTL-----EDEG 185
+ V + KD S + D++ + G+ + L + E
Sbjct: 134 HSIVRMPSGEFSRICKDLSSIGDTVVISVTKEGVKFSTAGDIGTANIVLRQNTTVDKPED 193
Query: 186 LLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLAP 245
+ IE+ E ++ + Y++ K ++ VTI +E+P+ +EY + + G + + LAP
Sbjct: 194 AIVIEMNEPVSLSFALRYMNSFTKATPLSETVTISLSSELPVVVEYKVAEMGYIRYYLAP 253
Query: 246 RVEE 249
++EE
Sbjct: 254 KIEE 257
>gb|AAF18324.1|AF140608_1 (AF140608) proliferating cell nuclear antigen [Danio rerio]
Length = 261
Score = 89.3 bits (218), Expect = 4e-17
Identities = 63/246 (25%), Positives = 120/246 (48%), Gaps = 13/246 (5%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++E LI EA + V+ GIS+++MD S V L+ L L + F Y D +GVN+
Sbjct: 14 KVLEALKDLITEACWDVSSSGISLQSMDSSHVSLVQLTLRSDGFDSYRCDRNLAMGVNLS 73
Query: 75 HLKKVLKRGKAKETLILRKGEENFLEISLQGTA-----TRTFKLPLIDVEEIEVDLPELP 129
+ K+LK ++ LR E+N ++L A +++ L+D++ ++ +PE
Sbjct: 74 SMSKILKCAGNEDIQTLR-AEDNADTLALVFEAQNQEKVSDYEMKLMDLDVEQLGIPEQE 132
Query: 130 FTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLT------LED 183
++ V + +D S + D++ ++ A GE +KL+ ED
Sbjct: 133 YSCVVKMPSGEFARICRDLSQIGDAVMISCAKDGVKFSASGELGTGNIKLSQTSNVDKED 192
Query: 184 EGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLL 243
E + IE+ E + + ++YL+ K + VT++ +P+ +E I D + + L
Sbjct: 193 EA-VTIEMNEPVQLIFALNYLNFFTKPTPLSRTVTLRMSAHIPLVVEDKIADLEHVKYYL 251
Query: 244 APRVEE 249
AP++E+
Sbjct: 252 APQIED 257
>sp|P31008|PCNA_PLAFK PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (CYCLIN)
>gi|422318|pir||S30224 proliferating cell nuclear
antigen - malaria parasite (Plasmodium falciparum)
>gi|9932|emb|CAA48673.1| (X68739) proliferating cell
nuclear antigen [Plasmodium falciparum]
Length = 274
Score = 88.2 bits (215), Expect = 8e-17
Identities = 69/266 (25%), Positives = 125/266 (46%), Gaps = 20/266 (7%)
Query: 4 EIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEV 63
E A +L E L+++A E G+ ++A+D + V L+ L+L S FS Y
Sbjct: 3 EAKLNNASILKKLFECIKDLVNDANVDADESGLKLQALDGNHVSLVSLHLLDSGFSHYRC 62
Query: 64 DGEETIGVNMDHLKKVLKRGKAKETLILRKGEE----NFLEISLQGTATRTFKLPLIDVE 119
D E +GVN+ L KV K A E++++ ++ NF+ + + F L L+ +E
Sbjct: 63 DRERVLGVNIASLNKVFKLCGANESVVISSKDDEDNLNFVFENNKEDKVTNFSLKLMSIE 122
Query: 120 EIEVDLP--ELPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEV 177
+++P E F A+V + + ++ S SD++ N +G + EV
Sbjct: 123 LDSLNIPDCEEGFDAEVELSSKELTNIFRNLSEFSDTVFIEIDSNCIKFTTKGIVGDAEV 182
Query: 178 KL-----TLEDEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYY 232
L T ED+ + I+ +++ K ++ I YL+ K AD V + + P++ +Y
Sbjct: 183 ALKPRDSTSEDDIGVTIKSKKKIKQSFAIKYLNLFSKSNILADVVVLGLSDSRPIEFKYE 242
Query: 233 IRDE---------GRLIFLLAPRVEE 249
I+D G + F LAP++++
Sbjct: 243 IKDTSPDSDTLKIGFVKFFLAPKMDD 268
>sp|Q00268|PCNA_DAUCA PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (CYCLIN)
Length = 264
Score = 87.4 bits (213), Expect = 1e-16
Identities = 59/244 (24%), Positives = 120/244 (49%), Gaps = 9/244 (3%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++++ L+++A F + G S++AMD S V L+ + L + F Y D ++G+N+
Sbjct: 14 KVMDSIKDLVNDANFDCSATGFSLQAMDSSHVALVAVLLRSEGFEHYRCDRNISMGMNLG 73
Query: 75 HLKKVLKRGKAKETLILRKGEEN----FLEISLQGTATRTFKLPLIDVEEIEVDLPELPF 130
++ K+LK + + ++ + + F+ S F++ L+D++ + +PE +
Sbjct: 74 NMAKMLKCAGNDDIITIKADDGSDTVTFMFESPTQDKIADFEMKLMDIDSEHLGIPEAEY 133
Query: 131 TAKVVILGDVIKEAVKDASLVSDSMKF-IAKEN-EFTMRAEGETQEVEVKLTL---EDEG 185
A V + KD S + D++ + KE +F+ R + T + + + E
Sbjct: 134 HAIVRMPSAEFARICKDLSSIGDTVVISVTKEGVKFSTRGDIGTANIVCRQNTTVDKPEE 193
Query: 186 LLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLAP 245
IE+ E + + Y++ K + VTI +E+P+ +EY I + G + F LAP
Sbjct: 194 ATVIEMNEPVSLTFALRYMNSFTKASPLSSTVTISLSSELPVVVEYKIAEMGYIRFYLAP 253
Query: 246 RVEE 249
++EE
Sbjct: 254 KIEE 257
>pir||S20592 proliferating cell nuclear antigen (clone 4.10) - carrot
Length = 264
Score = 85.8 bits (209), Expect = 4e-16
Identities = 59/244 (24%), Positives = 120/244 (49%), Gaps = 9/244 (3%)
Query: 15 QLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMD 74
+++++ L+++A F + G S++AMD S V L+ + L + F Y D ++G+N+
Sbjct: 14 KVMDSIKDLVNDANFDCSATGFSLQAMDSSHVALVAVLLRSEGFEHYRCDRNISMGMNLG 73
Query: 75 HLKKVLKRGKAKETLILRKGEEN----FLEISLQGTATRTFKLPLIDVEEIEVDLPELPF 130
++ K+LK + + ++ + + F+ S F++ L+D++ + +PE +
Sbjct: 74 NMAKMLKCAGNDDIITIKADDGSDTVTFMFESPTQDKIADFEMKLMDIDSEHLGIPEAEY 133
Query: 131 TAKVVILGDVIKEAVKDASLVSDSMKF-IAKEN-EFTMRAEGETQEVEVKLTL---EDEG 185
A V + KD S + D++ + KE +F+ R + T + + + E
Sbjct: 134 HAIVRMPSAEFARICKDLSSIGDTVVISVTKEGVKFSTRGDIGTANIVCRQNTTVDKPEE 193
Query: 186 LLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLAP 245
IE+ E + + Y++ K + VTI +E+P+ +EY I + G + F LAP
Sbjct: 194 ATVIEMNEPVSLTFALRYMNSFTKLSPLSSTVTISLSSELPVVVEYKIAEMGYIRFYLAP 253
Query: 246 RVEE 249
++EE
Sbjct: 254 KIEE 257
>sp|P22177|PCNA_SOYBN PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) (CYCLIN)
>gi|99946|pir||S14414 proliferating cell nuclear antigen
- soybean (fragment) >gi|18726|emb|CAA39239.1| (X55706)
proliferating cell nuclear antigen [Glycine max]
Length = 236
Score = 84.7 bits (206), Expect = 9e-16
Identities = 57/224 (25%), Positives = 110/224 (48%), Gaps = 9/224 (4%)
Query: 35 GISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMDHLKKVLKRGKAKETLILRKG 94
G S++AMD S V L+ L L + F Y D ++G+N++++ K+LK + + ++
Sbjct: 4 GFSLQAMDSSHVALVALLLRSEGFEHYRCDRNISMGMNLNNMAKMLKCAGNDDIITIKAD 63
Query: 95 EEN----FLEISLQGTATRTFKLPLIDVEEIEVDLPELPFTAKVVILGDVIKEAVKDASL 150
+ + F+ S F++ L+D++ + +PE + A V + KD S
Sbjct: 64 DGSDTVTFMFESPTQDKISDFEMKLMDIDSEHLGIPEAEYHAIVKMPSSEFARICKDLSS 123
Query: 151 VSDSMKF-IAKEN-EFTMRAEGETQEVEVKLTL---EDEGLLDIEVQEETKSAYGISYLS 205
+ D++ + KE +F+ + + T + + + E IE+ E + + Y++
Sbjct: 124 IGDTVVISVTKEGVKFSTKGDIGTANIVCRQNTSVDKPEEATVIEMNEPVSLTFALRYMN 183
Query: 206 DMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLAPRVEE 249
K ++ VTI NE+P+ +EY I + G + F LAP++EE
Sbjct: 184 SFTKATPLSNTVTISLSNELPVVVEYKIAEMGYVRFYLAPKIEE 227
>gi|9631761 similar to human PCNA, corresponds to Swiss-Prot Accession Number
P12004 [Paramecium bursaria Chlorella virus 1]
>gi|3334296|sp|Q84513|PCN1_CHVP1 PROLIFERATING CELL
NUCLEAR ANTIGEN HOMOLOG A193L >gi|7461877|pir||T17683
proliferating cell nuclear antigen-like protein A193L -
Chlorella virus PBCV-1 >gi|1181356|gb|AAC96561.1|
(U42580) similar to human PCNA, corresponds to
Swiss-Prot Accession Number P12004 [Paramecium bursaria
Chlorella virus 1]
Length = 262
Score = 83.5 bits (203), Expect = 2e-15
Identities = 49/239 (20%), Positives = 117/239 (48%), Gaps = 9/239 (3%)
Query: 16 LIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMDH 75
L + ++ + GI + A+D ++V L+ L L + F +Y+ + +GVN+ +
Sbjct: 21 LFDCLKEILHDVMLSFGPTGIRISALDGAKVSLVHLKLDSESFEEYKCEHTYELGVNVLN 80
Query: 76 LKKVLKRGKAKETLILR--KGEENFLEISLQG---TATRTFKLPLIDVEEIEVDLPELPF 130
+ K+L+ + ++++ R K + + +E+++Q + F + LI+++ +E+++ ++ F
Sbjct: 81 MFKLLRSAGSHDSILFRYLKNDPHMIELTIQNFEKNSLTKFNMKLIEIDSVEIEVGDIEF 140
Query: 131 TAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGE--TQEVEVKLTL--EDEGL 186
+V+ + + +D S ++D + + K +E + ++ T K + D G
Sbjct: 141 DTIIVMPANYFQRICRDMSDITDHLVIVKKGDEVSFNSDYTCVTDFASQKTIIGDSDNGQ 200
Query: 187 LDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLAP 245
+ + +S + + YL+ K G + V I P+ ++Y + G L F++AP
Sbjct: 201 ITCNNDTDYESKFSLKYLTSFCKASGMSSAVEIYLKESYPLILKYTVGSMGALKFVIAP 259
>pir||H71158 hypothetical protein PHS020 - Pyrococcus horikoshii
>gi|3256874|dbj|BAA29557.1| (AP000002) 97aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 97
Score = 76.5 bits (185), Expect = 3e-13
Identities = 33/91 (36%), Positives = 59/91 (64%)
Query: 30 KVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMDHLKKVLKRGKAKETL 89
+V E+G S++ + RV + + +P +F KY ++G+E + + L++VLKR K + L
Sbjct: 4 EVAEQGASLQIKEAKRVAFVKIYIPRGLFLKYNIEGKELVEIPWYDLERVLKRSKGSDIL 63
Query: 90 ILRKGEENFLEISLQGTATRTFKLPLIDVEE 120
IL+K ++ LE++ +G A RTFKLPL+ ++
Sbjct: 64 ILKKENKSVLEVTFEGAAIRTFKLPLLSPQK 94
>gb|AAB81177.1| (AF012212) proliferating cell nuclear antigen [Tetraselmis chui]
Length = 206
Score = 73.0 bits (176), Expect = 3e-12
Identities = 45/201 (22%), Positives = 91/201 (44%), Gaps = 9/201 (4%)
Query: 58 FSKYEVDGEETIGVNMDHLKKVLKRGKAKETLILRKGEE----NFLEISLQGTATRTFKL 113
F Y D ++G+N+ ++ K+LK + + ++ ++ F+ S F+L
Sbjct: 3 FEHYRCDRSLSMGLNLGNMAKMLKCAGNDDVITIKADDKPDSLTFMMESPSQDRVSDFEL 62
Query: 114 PLIDVEEIEVDLPELPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQ 173
L+D++ + +PE A V + + +D S + D++ ++ +G+
Sbjct: 63 KLMDIDSEHLGIPETEHQAVVKLPASEFQRICRDLSSIGDTVNISVTKDGVRFSTKGDIG 122
Query: 174 EVEVKLTL-----EDEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQ 228
+ + E + IE+QE + + YL+ K + VT+ E+P+
Sbjct: 123 SANISCRQNTSVDKPEEAVVIEMQEPVTLTFALRYLNSFAKATPLSSTVTLSMSKELPIV 182
Query: 229 MEYYIRDEGRLIFLLAPRVEE 249
+EY I+D G + F LAP++EE
Sbjct: 183 VEYRIQDMGFVKFYLAPKIEE 203
>gb|AAF65548.1|AF242302_1 (AF242302) proliferating cell nuclear antigen 2 [Toxoplasma gondii]
Length = 272
Score = 70.6 bits (170), Expect = 2e-11
Identities = 63/274 (22%), Positives = 120/274 (42%), Gaps = 47/274 (17%)
Query: 18 ETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMDHLK 77
E ++ + GIS+ +MD S V ++D+ L +F KY D +G+++ +L
Sbjct: 1 ECLKEMVTDVNLVCNASGISLDSMDGSHVAVVDVRLAVDLFHKYRCDRPVQLGLSVPNLL 60
Query: 78 KVLKRGKAKETLILRKG---------EENFLEISLQGTA---TRTFKLPLIDVEEIEVDL 125
L+ K+ ETL+ E+ L I+++ T + ++ L+DVE ++++
Sbjct: 61 LALQPVKSAETLVHLSSLHGDDEDDEEDTILHINIEDPESGDTWSMEVRLLDVESEQLEV 120
Query: 126 PE-LPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTLEDE 184
PE A V+ +++ V+ + +S+S+ + K ++ M+ V ++ E
Sbjct: 121 PEHTEHEATAVVRSKELQDLVRYLNSLSESI--VVKMDKTHMQLSARGDSVAASRKMQPE 178
Query: 185 GLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIR---------- 234
L+ T+ + YL+ +KG AD V I + +PMQ+ + ++
Sbjct: 179 SLV---CTNSTEHEFAARYLNMFLKGAVLADFVEIGCSHGLPMQISFRLKLQAERERDAK 235
Query: 235 --------------DEG-----RLIFLLAPRVEE 249
DEG L F LAPR+E+
Sbjct: 236 KKGADRLHDVKMDEDEGPQSRSTLSFYLAPRIED 269
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.315 0.136 0.359
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80044286
Number of Sequences: 2977
Number of extensions: 3117702
Number of successful extensions: 7507
Number of sequences better than 1.0e-10: 63
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 54
Number of HSP's that attempted gapping in prelim test: 7343
Number of HSP's gapped (non-prelim): 101
length of query: 249
length of database: 189,106,746
effective HSP length: 61
effective length of query: 188
effective length of database: 152,599,039
effective search space: 28688619332
effective search space used: 28688619332
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 42 (22.0 bits)
S2: 164 (68.3 bits)