BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1472 (vorA) DE:KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA
(EC 1.-.-.-) (VOR)
(395 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||B75047 probable 2-oxoisovalerate--ferredoxin oxidoreductase... 795 0.0
pir||A71114 probable ferredoxin oxidoreductase alpha subunit - P... 753 0.0
sp|O58413|VORA_PYRHO KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA... 753 0.0
sp|Q51801|VORA_PYRFU KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA... 742 0.0
sp|Q51804|PORA_PYRFU PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX... 389 e-107
pir||G75046 pyruvate synthase (EC 1.2.7.1) alpha chain PAB1475 -... 383 e-105
pir||E71114 probable ferredoxin oxidoreductase alpha-2 subunit -... 374 e-102
sp|O73986|PORA_PYRHO PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX... 373 e-102
sp|Q57715|PORA_METJA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX... 356 3e-97
emb|CAC11767.1| (AL445064) probable 2-ketovalerate ferredoxin ox... 353 2e-96
gb|AAF91264.1|AF230199_6 (AF230199) pyruvate oxidoreductase alph... 349 4e-95
sp|P56810|PORA_METTH PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX... 332 5e-90
gb|AAK41454.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin... 326 3e-88
sp|O05651|PORA_THEMA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX... 323 2e-87
emb|CAA59457.1| (X85171) alpha subunit of pyruvate ferredoxin ox... 323 2e-87
gi|11499291 pyruvate ferredoxin oxidoreductase, subunit alpha (p... 313 2e-84
gb|AAK42867.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin... 295 6e-79
pir||F64658 pyruvate synthase (EC 1.2.7.1) alpha chain - Helicob... 270 3e-71
gb|AAC02293.1| (AF013980) pyruvate:ferredoxin oxidoreductase alp... 269 3e-71
pir||H71857 pyruvate ferrodoxin oxidoreductase - Helicobacter py... 268 6e-71
gi|11499635 2-ketoisovalerate ferredoxin oxidoreductase, subunit... 246 4e-64
gb|AAK42308.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin... 237 1e-61
pir||S74041 pyruvate synthase (EC 1.2.7.1) alpha chain - Sulfolo... 237 1e-61
gb|AAC38206.1| (AF021092) PorA subunit of pyruvate:flavodoxin ox... 226 5e-58
gb|AAD55756.1|AF132673_1 (AF132673) pyruvate:ferredoxin oxidored... 145 9e-34
emb|CAB43935.1| (Y17727) pyruvate ferredoxin oxidoreductase [Clo... 142 8e-33
emb|CAB43933.1| (Y17726) pyruvate ferredoxin oxidoreductase [Clo... 141 1e-32
sp|P03833|NIFJ_KLEPN PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|4382... 140 3e-32
pir||QQKBFP pyruvate (flavodoxin) dehydrogenase nifJ (EC 1.2.99.... 140 3e-32
sp|P19543|NIFJ_ENTAG PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|4690... 139 4e-32
dbj|BAA95605.1| (AB042412) pyruvate:ferredoxin oxidoreductase al... 139 5e-32
gb|AAC83148.1| (AF061850) putative pyruvate oxidoreductase; POR ... 139 5e-32
pir||F82447 pyruvate-flavoredoxin oxidoreductase VCA0530 [import... 138 1e-31
pir||B70400 ferredoxin oxidoreductase alpha subunit - Aquifex ae... 136 4e-31
pir||C70403 ferredoxin oxidoreductase alpha subunit - Aquifex ae... 134 2e-30
sp|P52965|NIFJ_SYNY3 PUTATIVE PYRUVATE-FLAVODOXIN OXIDOREDUCTASE... 132 9e-30
sp|P52647|NIFJ_ECOLI PROBABLE PYRUVATE-FLAVODOXIN OXIDOREDUCTASE... 131 2e-29
pir||G71262 probable pyruvate (flavodoxin) dehydrogenase (EC 1.2... 129 6e-29
emb|CAA70873.1| (Y09702) pyruvate-ferredoxin oxidoreductase [Des... 129 7e-29
pdb|1B0P|A Chain A, Crystal Structure Of Pyruvate-Ferredoxin Oxi... 129 7e-29
pir||A81294 pyruvate-flavodoxin oxidoreductase Cj1476c [imported... 128 1e-28
sp|Q06879|NIFJ_ANASP PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|2126... 122 7e-27
emb|CAB43934.1| (Y17727) pyruvate ferredoxin oxidoreductase [Clo... 120 4e-26
sp|Q53046|NIFJ_RHORU PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|6288... 118 8e-26
gb|AAB49653.1| (U30149) pyruvate:ferredoxin oxidoreductase [Enta... 118 8e-26
pir||S70963 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) - ... 118 8e-26
pir||C75168 2-ketoglutarate ferredoxin oxidoreductase, chain alp... 113 4e-24
emb|CAA57480.1| (X81893) nifJ [Enterobacter agglomerans] 109 4e-23
dbj|BAB12024.1| (AB021127) pyruvate:NADP+ oxidoreductase [Euglen... 107 2e-22
pir||S58236 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) - ... 106 5e-22
pir||H72214 hypothetical protein TM1759 - Thermotoga maritima (s... 104 2e-21
pir||B71047 probable ferredoxin oxidoreductase alpha subunit - P... 103 3e-21
pir||T43259 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) pf... 102 5e-21
pir||F71046 probable ferredoxin oxidoreductase alpha subunit - P... 102 5e-21
sp|Q57724|KORA_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KET... 102 9e-21
pir||F75168 2-ketoglutarate ferredoxin oxidoreductase, chain alp... 101 2e-20
pir||H69004 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.... 100 3e-20
sp|O27112|KORA_METTH 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KET... 100 3e-20
pir||T43258 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) pf... 100 4e-20
gb|AAD55754.1|AF132546_1 (AF132546) pyruvate:ferredoxin oxidored... 94 3e-18
sp|O26800|VORB_METTH KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORB... 92 1e-17
pir||A69194 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al... 92 1e-17
pir||H81399 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.... 91 2e-17
pir||T18528 probable pyruvate (flavodoxin) dehydrogenase (EC 1.2... 89 9e-17
gb|AAD55757.1|AF146519_1 (AF146519) putative pyruvate:ferredoxin... 88 2e-16
pir||H72323 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.... 86 6e-16
pir||E64593 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al... 86 8e-16
gi|11498080 2-ketoglutarate ferredoxin oxidoreductase, subunit a... 83 4e-15
pir||G71919 chain of 2-oxoglutarate oxidoreductase - Helicobacte... 83 4e-15
pir||A72627 probable 2-oxoacid--ferredoxin oxidoreductase, alpha... 83 4e-15
gb|AAC38211.1| (AF021094) OorA subunit of 2-oxoglutarate:accepto... 82 9e-15
>pir||B75047 probable 2-oxoisovalerate--ferredoxin oxidoreductase (EC 1.2.7.-)
alpha chain PAB1472 [similarity] - Pyrococcus abyssi
(strain Orsay) >gi|5458784|emb|CAB50271.1| (AJ248287)
KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (EC 1.-.-.-)
(VOR) [Pyrococcus abyssi]
Length = 395
Score = 795 bits (2032), Expect = 0.0
Identities = 395/395 (100%), Positives = 395/395 (100%)
Query: 1 MVEYKPIKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPV 60
MVEYKPIKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPV
Sbjct: 1 MVEYKPIKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPV 60
Query: 61 ESEHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWS 120
ESEHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWS
Sbjct: 61 ESEHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWS 120
Query: 121 VWDDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEI 180
VWDDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEI
Sbjct: 121 VWDDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEI 180
Query: 181 VNMIPQELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKD 240
VNMIPQELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKD
Sbjct: 181 VNMIPQELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKD 240
Query: 241 VGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRW 300
VGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRW
Sbjct: 241 VGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRW 300
Query: 301 FRPFPREELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIMKNYIVGLGG 360
FRPFPREELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIMKNYIVGLGG
Sbjct: 301 FRPFPREELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIMKNYIVGLGG 360
Query: 361 RDFTVSDVKAIAEDMKKVIESGKLDREVEWYHLKR 395
RDFTVSDVKAIAEDMKKVIESGKLDREVEWYHLKR
Sbjct: 361 RDFTVSDVKAIAEDMKKVIESGKLDREVEWYHLKR 395
>pir||A71114 probable ferredoxin oxidoreductase alpha subunit - Pyrococcus
horikoshii >gi|3257088|dbj|BAA29771.1| (AP000003) 397aa
long hypothetical ferredoxin oxidoreductase alpha
subunit [Pyrococcus horikoshii]
Length = 397
Score = 753 bits (1923), Expect = 0.0
Identities = 363/394 (92%), Positives = 384/394 (97%)
Query: 2 VEYKPIKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVE 61
+EY PIKKVVSGNYAAAYA LHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVE
Sbjct: 4 MEYNPIKKVVSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVE 63
Query: 62 SEHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSV 121
SEHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAG+RLPIVMV+VNRAMAPPWSV
Sbjct: 64 SEHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGSRLPIVMVNVNRAMAPPWSV 123
Query: 122 WDDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIV 181
WDDQTDSLSQRDTGWMQFYAENNQEVYDGVLMA+KVAETVN+P M++ESAFILSHTYE+V
Sbjct: 124 WDDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAYKVAETVNIPTMIIESAFILSHTYEVV 183
Query: 182 NMIPQELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDV 241
NMIPQELVDEFLPPRKPLY+L DFENPIAVGALATPADYYEFRYK+A+AHEEAKKVIK V
Sbjct: 184 NMIPQELVDEFLPPRKPLYTLTDFENPIAVGALATPADYYEFRYKIAKAHEEAKKVIKSV 243
Query: 242 GREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWF 301
G+EFGERFGRDYS+MIE YI+DADFVFMGMGSLMGTVKEAV+LLRK+GYKVGYAKVRWF
Sbjct: 244 GKEFGERFGRDYSKMIETGYIEDADFVFMGMGSLMGTVKEAVDLLRKEGYKVGYAKVRWF 303
Query: 302 RPFPREELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIMKNYIVGLGGR 361
RPFP+EELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYN G RPIMK+YIVGLGGR
Sbjct: 304 RPFPKEELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNTGVRPIMKDYIVGLGGR 363
Query: 362 DFTVSDVKAIAEDMKKVIESGKLDREVEWYHLKR 395
DFTV DVKAIAEDMKKV+ESGKLD+E+EWYHLKR
Sbjct: 364 DFTVRDVKAIAEDMKKVVESGKLDKEIEWYHLKR 397
>sp|O58413|VORA_PYRHO KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (VOR) (2-OXOISOVALERATE
OXIDOREDUCTASE ALPHA CHAIN) (2-OXOISOVALERATE-FERREDOXIN
OXIDOREDUCTASE ALPHA SUBUNIT)
Length = 394
Score = 753 bits (1923), Expect = 0.0
Identities = 363/394 (92%), Positives = 384/394 (97%)
Query: 2 VEYKPIKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVE 61
+EY PIKKVVSGNYAAAYA LHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVE
Sbjct: 1 MEYNPIKKVVSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVE 60
Query: 62 SEHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSV 121
SEHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAG+RLPIVMV+VNRAMAPPWSV
Sbjct: 61 SEHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGSRLPIVMVNVNRAMAPPWSV 120
Query: 122 WDDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIV 181
WDDQTDSLSQRDTGWMQFYAENNQEVYDGVLMA+KVAETVN+P M++ESAFILSHTYE+V
Sbjct: 121 WDDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAYKVAETVNIPTMIIESAFILSHTYEVV 180
Query: 182 NMIPQELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDV 241
NMIPQELVDEFLPPRKPLY+L DFENPIAVGALATPADYYEFRYK+A+AHEEAKKVIK V
Sbjct: 181 NMIPQELVDEFLPPRKPLYTLTDFENPIAVGALATPADYYEFRYKIAKAHEEAKKVIKSV 240
Query: 242 GREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWF 301
G+EFGERFGRDYS+MIE YI+DADFVFMGMGSLMGTVKEAV+LLRK+GYKVGYAKVRWF
Sbjct: 241 GKEFGERFGRDYSKMIETGYIEDADFVFMGMGSLMGTVKEAVDLLRKEGYKVGYAKVRWF 300
Query: 302 RPFPREELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIMKNYIVGLGGR 361
RPFP+EELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYN G RPIMK+YIVGLGGR
Sbjct: 301 RPFPKEELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNTGVRPIMKDYIVGLGGR 360
Query: 362 DFTVSDVKAIAEDMKKVIESGKLDREVEWYHLKR 395
DFTV DVKAIAEDMKKV+ESGKLD+E+EWYHLKR
Sbjct: 361 DFTVRDVKAIAEDMKKVVESGKLDKEIEWYHLKR 394
>sp|Q51801|VORA_PYRFU KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (VOR) (2-OXOISOVALERATE
OXIDOREDUCTASE ALPHA CHAIN) (2-OXOISOVALERATE-FERREDOXIN
OXIDOREDUCTASE ALPHA SUBUNIT) >gi|11280154|pir||T45085
2-oxoisovalerate--ferredoxin oxidoreductase (EC 1.2.7.-)
alpha chain vorA - Pyrococcus furiosus
>gi|1197360|emb|CAA59502.1| (X85250) 2-ketovalerate
ferredoxin oxidoreductase alpha-2 [Pyrococcus furiosus]
Length = 394
Score = 742 bits (1896), Expect = 0.0
Identities = 360/394 (91%), Positives = 382/394 (96%)
Query: 2 VEYKPIKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVE 61
+EYKPI+KVVSGNYAAAYA LHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVE
Sbjct: 1 MEYKPIRKVVSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVE 60
Query: 62 SEHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSV 121
SEHSAMAACIGASATGAR FTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSV
Sbjct: 61 SEHSAMAACIGASATGARTFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSV 120
Query: 122 WDDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIV 181
WDDQTDSLSQRDTGWMQFYAENNQEVYDGVLMA+KVAETVNVPAMVVESAFILSHTY++V
Sbjct: 121 WDDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAYKVAETVNVPAMVVESAFILSHTYDVV 180
Query: 182 NMIPQELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDV 241
MIPQELVDEFLPPRKPLYSLA+F+ PIAVGALATP DYYEFRYKLA+AHEEAKKVIK+V
Sbjct: 181 EMIPQELVDEFLPPRKPLYSLANFDEPIAVGALATPNDYYEFRYKLAKAHEEAKKVIKEV 240
Query: 242 GREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWF 301
G+EFGERFGRDYS+MIE YIDDADFVFMGMGSLMGTVKEAV+LLRK+GYKVGYAKVRWF
Sbjct: 241 GKEFGERFGRDYSQMIETGYIDDADFVFMGMGSLMGTVKEAVDLLRKEGYKVGYAKVRWF 300
Query: 302 RPFPREELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIMKNYIVGLGGR 361
RPFP+EEL+EIAESVKGIAVLDRNFSFGQEGILFTE+KGALYN+ A P+MKNYIVGLGGR
Sbjct: 301 RPFPKEELVEIAESVKGIAVLDRNFSFGQEGILFTESKGALYNSSAHPLMKNYIVGLGGR 360
Query: 362 DFTVSDVKAIAEDMKKVIESGKLDREVEWYHLKR 395
D TV D+KAIA+DMKKVIESGK+D+EV WYHLKR
Sbjct: 361 DVTVKDIKAIADDMKKVIESGKVDKEVVWYHLKR 394
>sp|Q51804|PORA_PYRFU PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
SUBUNIT) >gi|11280155|pir||T45088 pyruvate synthase (EC
1.2.7.1) alpha-2 chain [imported] - Pyrococcus furiosus
>gi|1197363|emb|CAA59505.1| (X85250) pyruvate ferredoxin
oxidoreductase alpha-2 [Pyrococcus furiosus]
Length = 396
Score = 389 bits (989), Expect = e-107
Identities = 200/391 (51%), Positives = 274/391 (69%), Gaps = 3/391 (0%)
Query: 6 PIKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHS 65
PI+KV+ N AAA+A A+ +V+AA+PITP T I EKI+EF+ANGE D ++I VESEHS
Sbjct: 2 PIRKVMKANEAAAWAAKLAKPKVIAAFPITPSTLIPEKISEFVANGELDAEFIKVESEHS 61
Query: 66 AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQ 125
A++AC+GA+A G R FTAT++QGLALMHE+L AAG RLPIVM NRA++ P ++W+D
Sbjct: 62 AISACVGAAAAGVRTFTATASQGLALMHEILFIAAGMRLPIVMAIGNRALSAPINIWNDW 121
Query: 126 TDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVA--ETVNVPAMVVESAFILSHTYEIVNM 183
D++SQRDTGWMQFYAENNQE D +L+A+KVA E V +PAMV AFIL+HT E V +
Sbjct: 122 QDTISQRDTGWMQFYAENNQEALDLILIAYKVAEDERVLLPAMVGFDAFILTHTVEPVEI 181
Query: 184 IPQELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGR 243
QE+VDEFL +P ++ D PI G+LA PA Y E RY + A E AKKVI +
Sbjct: 182 PDQEVVDEFLGEYEPKHAYIDPARPITQGSLAFPAHYMESRYTVWEAMERAKKVIDEAFA 241
Query: 244 EFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWFRP 303
EF ++FGR Y + IE+ +DAD +F+ MGSL GT+ E ++ R++GYKVG AK+ +RP
Sbjct: 242 EFEKKFGRKY-QKIEEYKTEDADIIFVTMGSLAGTLNEWIDKKREEGYKVGAAKITVYRP 300
Query: 304 FPREELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIMKNYIVGLGGRDF 363
FP EE+ E+A+ K +A L++N + G G +FT+A AL N +P+M ++IVG GGRD
Sbjct: 301 FPVEEIRELAKKAKVLAFLEKNITIGLYGAVFTDASAALINESEKPLMVDFIVGHGGRDV 360
Query: 364 TVSDVKAIAEDMKKVIESGKLDREVEWYHLK 394
T + + E +K ++ GK++ + W L+
Sbjct: 361 TFNQLDEALEIAEKALKEGKVENPINWIGLR 391
>pir||G75046 pyruvate synthase (EC 1.2.7.1) alpha chain PAB1475 - Pyrococcus
abyssi (strain Orsay) >gi|5458781|emb|CAB50268.1|
(AJ248287) PYRUVATE SYNTHASE SUBUNIT PORA (EC 1.2.7.1)
(PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR) [Pyrococcus
abyssi]
Length = 395
Score = 383 bits (972), Expect = e-105
Identities = 196/392 (50%), Positives = 274/392 (69%), Gaps = 3/392 (0%)
Query: 6 PIKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHS 65
PI+ V+ N AAA+A A+ +V+AA+PITP T + EKI+EF+ANGE D ++I VESEHS
Sbjct: 2 PIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHS 61
Query: 66 AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQ 125
A++A +GASA G R FTAT++QGLALMHE+L AAG RLPIVM NRA++ P ++W+D
Sbjct: 62 AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDW 121
Query: 126 TDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVA--ETVNVPAMVVESAFILSHTYEIVNM 183
D++SQRDTGW+QFYAENNQE D +L+A+KVA E V +PAMV AFIL+HT E V +
Sbjct: 122 QDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEI 181
Query: 184 IPQELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGR 243
QE+VDEFL +P ++ D + PI G LA PA Y E RY + A E A+KVI +
Sbjct: 182 PDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFA 241
Query: 244 EFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWFRP 303
EF ++FGR Y + IE+ DDA+ +F+ MGSL GT+K+ V+ R++GYKVG AK+ +RP
Sbjct: 242 EFEKKFGRKY-QKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300
Query: 304 FPREELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIMKNYIVGLGGRDF 363
FP EE+ E+A+ K +A ++++ S G G +FT+A AL N +P+M ++I GLGGRD
Sbjct: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV 360
Query: 364 TVSDVKAIAEDMKKVIESGKLDREVEWYHLKR 395
T + + K+ +E GK+++ + W L++
Sbjct: 361 TFNQLDEALSIAKEALEKGKVEKPIHWIGLRK 392
>pir||E71114 probable ferredoxin oxidoreductase alpha-2 subunit - Pyrococcus
horikoshii >gi|3257092|dbj|BAA29775.1| (AP000003) 398aa
long hypothetical ferredoxin oxidoreductase alpha-2
subunit [Pyrococcus horikoshii]
Length = 398
Score = 374 bits (950), Expect = e-102
Identities = 192/394 (48%), Positives = 272/394 (68%), Gaps = 3/394 (0%)
Query: 4 YKPIKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESE 63
+ PI+ V+ N AAA+A A+ +V+AA+PITP T + EKI+EF+ANGE D ++I VESE
Sbjct: 3 FMPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESE 62
Query: 64 HSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWD 123
HSA++A +GASA G R FTAT++QGLALMHE+L AAG RLPIVM NR+++ P ++W+
Sbjct: 63 HSAISAVVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRSLSAPINIWN 122
Query: 124 DQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVA--ETVNVPAMVVESAFILSHTYEIV 181
D DS+SQRDTGW+QFYAENNQE D +L+A+KVA E V +PAMV AFIL+HT E V
Sbjct: 123 DWQDSISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPV 182
Query: 182 NMIPQELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDV 241
+ QE+VDEFL +P ++ D + PI G LA PA Y E +Y + A E+A+KVI +
Sbjct: 183 EIPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEAKYLVWDAMEKARKVIDEA 242
Query: 242 GREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWF 301
EF +RFGR Y + IE+ DDA+ +F+ MGSL GT+K+ V+ R++GYKVG AK+ +
Sbjct: 243 FAEFEKRFGRKY-QKIEEYKTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVY 301
Query: 302 RPFPREELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIMKNYIVGLGGR 361
RPFP EE+ +A+ K + ++++ S G G +F +A AL N RP+M ++I GLGGR
Sbjct: 302 RPFPVEEIRALAKKAKVLGFIEKDISIGLYGAVFIDASAALVNESERPLMLDFIAGLGGR 361
Query: 362 DFTVSDVKAIAEDMKKVIESGKLDREVEWYHLKR 395
D T + ++ +E G++++ + W L++
Sbjct: 362 DVTFGQLDDALRIAEEALEKGEVEKPIHWIGLRK 395
>sp|O73986|PORA_PYRHO PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
SUBUNIT)
Length = 395
Score = 373 bits (948), Expect = e-102
Identities = 192/392 (48%), Positives = 271/392 (68%), Gaps = 3/392 (0%)
Query: 6 PIKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHS 65
PI+ V+ N AAA+A A+ +V+AA+PITP T + EKI+EF+ANGE D ++I VESEHS
Sbjct: 2 PIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHS 61
Query: 66 AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQ 125
A++A +GASA G R FTAT++QGLALMHE+L AAG RLPIVM NR+++ P ++W+D
Sbjct: 62 AISAVVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRSLSAPINIWNDW 121
Query: 126 TDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVA--ETVNVPAMVVESAFILSHTYEIVNM 183
DS+SQRDTGW+QFYAENNQE D +L+A+KVA E V +PAMV AFIL+HT E V +
Sbjct: 122 QDSISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEI 181
Query: 184 IPQELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGR 243
QE+VDEFL +P ++ D + PI G LA PA Y E +Y + A E+A+KVI +
Sbjct: 182 PDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEAKYLVWDAMEKARKVIDEAFA 241
Query: 244 EFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWFRP 303
EF +RFGR Y + IE+ DDA+ +F+ MGSL GT+K+ V+ R++GYKVG AK+ +RP
Sbjct: 242 EFEKRFGRKY-QKIEEYKTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300
Query: 304 FPREELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIMKNYIVGLGGRDF 363
FP EE+ +A+ K + ++++ S G G +F +A AL N RP+M ++I GLGGRD
Sbjct: 301 FPVEEIRALAKKAKVLGFIEKDISIGLYGAVFIDASAALVNESERPLMLDFIAGLGGRDV 360
Query: 364 TVSDVKAIAEDMKKVIESGKLDREVEWYHLKR 395
T + ++ +E G++++ + W L++
Sbjct: 361 TFGQLDDALRIAEEALEKGEVEKPIHWIGLRK 392
>sp|Q57715|PORA_METJA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
SUBUNIT) >gi|2127892|pir||D64333 pyruvate synthase (EC
1.2.7.1) alpha chain - Methanococcus jannaschii
>gi|1590995|gb|AAB98254.1| (U67482) pyruvate ferredoxin
oxidoreductase, subunit alpha (porA) [Methanococcus
jannaschii]
Length = 389
Score = 356 bits (903), Expect = 3e-97
Identities = 190/390 (48%), Positives = 256/390 (64%), Gaps = 13/390 (3%)
Query: 9 KVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMA 68
KV++G AAA A A V V+AAYPITPQT+ +EK+AEF+ANGE D +YI VESEHSAM+
Sbjct: 8 KVITGTSAAAEAAKLADVDVIAAYPITPQTTCVEKLAEFVANGELDAEYIKVESEHSAMS 67
Query: 69 ACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQTDS 128
ACIGA+ATGAR FTAT++QGLALMHEML A+G RLPIVM+ NRA++ P ++W+D DS
Sbjct: 68 ACIGAAATGARTFTATASQGLALMHEMLFIASGMRLPIVMMVANRALSAPINIWNDHQDS 127
Query: 129 LSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNV--PAMVVESAFILSHTYEIVNMIPQ 186
+++RD+GW+Q Y E+NQE D ++ A+K+AE +V P MV FIL+HT E V +
Sbjct: 128 IAERDSGWIQIYVEDNQETLDSIIQAYKIAENEDVLLPVMVCLDGFILTHTVEPVTIPKA 187
Query: 187 ELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGREFG 246
E V EFL +P ++ D + PI G + P Y E R ++ A E AKKVI+DV EF
Sbjct: 188 ERVREFLGVYEPKHAYLDPDRPITQGPVGVPDCYMETRKQIEEAMERAKKVIRDVNEEFA 247
Query: 247 ERFGRDYSEMIEKAY-IDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWFRPFP 305
E F R Y + +AY +D+AD V + MGS+ GT+K ++ L+K+G VG ++R FRPFP
Sbjct: 248 EWFKRKYGNGLVEAYNLDNADTVLVAMGSVCGTIKYVIDELKKEGKNVGLLRIRAFRPFP 307
Query: 306 REELLEIAESVKGIAVLDRNFSFG-QEGILFTEAKGALYNNGARPIMKNYIVGLGGRDFT 364
+E++ E+ + IAVLD+N S G +G L E L N + NYIVGLGGRD
Sbjct: 308 KEDVKELLKDANNIAVLDKNISLGFNKGALGIEMASILKNKK----VCNYIVGLGGRDIK 363
Query: 365 VSDVKAIAEDMKKVIESGKLDREVEWYHLK 394
+ D+K I ++K + L W LK
Sbjct: 364 IDDIKTIINHVEKAEDDSTL-----WVGLK 388
>emb|CAC11767.1| (AL445064) probable 2-ketovalerate ferredoxin oxidoreductase
alpha-2 chain [Thermoplasma acidophilum]
Length = 402
Score = 353 bits (897), Expect = 2e-96
Identities = 178/398 (44%), Positives = 260/398 (64%), Gaps = 11/398 (2%)
Query: 1 MVEYKPIKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPV 60
M + +++GN A AY ARV+ ++AYPITPQT+I+EK+A IAN E D +Y+ V
Sbjct: 11 MKSVNEFRTIMTGNDAVAYGAKLARVKFISAYPITPQTTIVEKLASMIANDELDAKYVEV 70
Query: 61 ESEHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWS 120
ESEHSA+AA + TG R +TATS+ GL MHEMLHW AG RLPIVM VNRA+ PPW+
Sbjct: 71 ESEHSALAAVFASELTGVRSYTATSSHGLLYMHEMLHWVAGQRLPIVMSVVNRAIGPPWN 130
Query: 121 VWDDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAET--VNVPAMVVESAFILSHTY 178
+W DQ+D+++QRDTGWMQ Y+E+NQE D ++M +K+AE V +P M +E AFILSHT
Sbjct: 131 IWADQSDTINQRDTGWMQVYSESNQEAMDTIIMGYKIAENSGVMLPLMSMEDAFILSHTS 190
Query: 179 EIVNMIPQELVDEFLPPRKPLYSLADFENPIAVGALATP-ADYYEFRYKLARAHEEAKKV 237
E V M Q+LV+E+LP + + D ENP+ G+ TP + EF+ + + A+KV
Sbjct: 191 EPVTMRDQDLVNEYLPDLDLKFRI-DPENPMGYGSYDTPDGSFMEFKKDMIDSMNNARKV 249
Query: 238 IKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAK 297
IK+ ++F E F +Y +IE+ +DDAD+ + MG++ T + ++ LR+ G +G +
Sbjct: 250 IKEETQKFNEMFETNYGALIERYRMDDADYAIIAMGTVASTARFVIDRLRENGLNIGLIR 309
Query: 298 VRWFRPFPREELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIMKNYIVG 357
+R+FRPFP +E+LE ++VK V+DR+ SFG G+ ++E LY P+ ++IVG
Sbjct: 310 IRYFRPFPYDEILEDLKNVKSAGVIDRSVSFGLAGVTYSEVISGLYGRINIPV-SSFIVG 368
Query: 358 LGGRDFTVSDVKAIAEDMKKVIESGKLDREVEWYHLKR 395
+GGRD + D+++IAE I +G W ++KR
Sbjct: 369 IGGRDVRIEDIESIAE----TIRNGSTG--THWINVKR 400
>gb|AAF91264.1|AF230199_6 (AF230199) pyruvate oxidoreductase alpha subunit [Methanococcus
maripaludis]
Length = 387
Score = 349 bits (885), Expect = 4e-95
Identities = 190/393 (48%), Positives = 260/393 (65%), Gaps = 19/393 (4%)
Query: 9 KVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMA 68
KV++G AAA A A V V+AAYPITPQT+ +EK+A+F+ANGE + +YI VESEHSAM+
Sbjct: 5 KVITGTSAAAEAAKLADVDVIAAYPITPQTTCVEKLADFVANGELNAEYIKVESEHSAMS 64
Query: 69 ACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQTDS 128
A IGASA GAR FTATS+QGLALMHE+L AAG R+P+VM++ NRA++ P ++W+DQ DS
Sbjct: 65 ASIGASAAGARAFTATSSQGLALMHEVLFAAAGMRVPVVMMNANRALSAPINIWNDQQDS 124
Query: 129 LSQRDTGWMQFYAENNQEVYDGVLMAFKVA--ETVNVPAMVVESAFILSHTYEIVNMIPQ 186
LSQRDTGW+Q YAE+NQEV D V+ AFK+A E V +P MV FIL+HT E V + Q
Sbjct: 125 LSQRDTGWIQLYAEDNQEVLDLVIQAFKIAEDEKVLLPVMVNLDGFILTHTVEPVTLPKQ 184
Query: 187 ELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGREFG 246
E V +F+ +P ++ D + P+ GAL P Y E RY + A E AKKVI DV F
Sbjct: 185 ENVLDFIGTYEPKHAYLDPKKPMTQGALGDPNYYMETRYAIETAMENAKKVIADVHDAFA 244
Query: 247 ERFGRDYSE-MIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWFRPFP 305
E+F R Y +IE ++ A+ V + MGS+ GT+K+ ++L +K+G ++G K+R +RP P
Sbjct: 245 EKFNRAYGNGLIESYNLEKAENVIVAMGSICGTIKDMIDLKKKEGVEIGLLKIRCYRPLP 304
Query: 306 REELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIMK----NYIVGLGGR 361
E + + ++ K +A+LD++ S G KGA+Y + A + NYIVGLGGR
Sbjct: 305 IEMIKDALKNAKNVAILDKSISLGMN-------KGAIYADVASHLKDKKTVNYIVGLGGR 357
Query: 362 DFTVSDVKAIAEDMKKVIESGKLDREVEWYHLK 394
D T D+ I +D+ ++ E GK W LK
Sbjct: 358 DITPEDILGIYDDV-EISEDGK----TNWIGLK 385
>sp|P56810|PORA_METTH PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
SUBUNIT) >gi|7449945|pir||E69099 pyruvate synthase (EC
1.2.7.1) alpha chain - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622870|gb|AAB86209.1| (AE000929) pyruvate
oxidoreductase, alpha subunit [Methanobacterium
thermoautotrophicum]
Length = 383
Score = 332 bits (842), Expect = 5e-90
Identities = 177/390 (45%), Positives = 253/390 (64%), Gaps = 14/390 (3%)
Query: 7 IKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSA 66
+ KV+S N A A A A+ +V+ YPITPQTSI E +A+F+A+GE +YI VESEHSA
Sbjct: 2 VLKVISANQAVAEAAKLAKPKVIPVYPITPQTSISEYLAKFVADGELKAEYIRVESEHSA 61
Query: 67 MAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQT 126
M+AC+GAS G RVFTATS+QGLALMHE+++ AAG R PIVM + NRA++ P S+W+DQ
Sbjct: 62 MSACVGASGAGVRVFTATSSQGLALMHEIVYAAAGLRNPIVMANANRALSAPLSIWNDQQ 121
Query: 127 DSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAE--TVNVPAMVVESAFILSHTYEIVNMI 184
DS+++RD+GWMQ Y E+ QE D VL++++V+E V +P+MV FIL+HT E V++
Sbjct: 122 DSIAERDSGWMQIYVESGQEALDSVLLSYRVSEDRDVLLPSMVCLDGFILTHTVEPVDIP 181
Query: 185 PQELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGRE 244
QE VD FLP +P L D + P+++G P Y E RY++ +A E ++K+I+ RE
Sbjct: 182 SQEDVDSFLPEFQPQVML-DPDEPMSLGTFTDPDYYMEARYEVEKAMERSRKIIERACRE 240
Query: 245 FGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWFRPF 304
F E FGR+Y ++E+ +DA+ + + MGS+ T++E ++ LR +G VG KVR RPF
Sbjct: 241 FSEMFGREYG-LVEEYRCEDAEIILVAMGSVCSTLREVIDELRDKGKAVGLLKVRVHRPF 299
Query: 305 PREELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIMKNYIVGLGGRDFT 364
P EE+ + +AVLD+N +F G L+TE L + + +IVGLGGRD T
Sbjct: 300 PAEEIKSAVRNASKVAVLDKNITFSVGGALYTEISALLRDRE----VYGFIVGLGGRDIT 355
Query: 365 VSDVKAIAEDMKKVIESGKLDREVEWYHLK 394
+ ++ I V + +R V W LK
Sbjct: 356 PAHIEEI------VRRTENPERSVTWIGLK 379
>gb|AAK41454.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase
alpha chain) (porA-1) [Sulfolobus solfataricus]
Length = 385
Score = 326 bits (827), Expect = 3e-88
Identities = 166/365 (45%), Positives = 240/365 (65%), Gaps = 6/365 (1%)
Query: 13 GNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMAACIG 72
GN+A AYAV A+ +V+A +PITPQT+++EK++E+I++ E + I VESEHSA+A+ G
Sbjct: 13 GNHAVAYAVKQAKPKVLAVFPITPQTTMLEKLSEYISSEELKAELIKVESEHSALASIYG 72
Query: 73 ASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQTDSLSQR 132
A+ GARVFTATS+QGL M EM++WA G R+PIV RA+A PWS+WDD D +S+R
Sbjct: 73 AALAGARVFTATSSQGLLYMTEMIYWAGGQRVPIVAAVATRAIAEPWSIWDDHQDFVSKR 132
Query: 133 DTGWMQFYAENNQEVYDGVLMAFKVA--ETVNVPAMVVESAFILSHTYEIVNMIPQELVD 190
D W+Q AEN QE YD + AF+++ E V +P M+ FIL+HT E + ++ VD
Sbjct: 133 DAIWIQIMAENVQEAYDMTIQAFRISEDERVILPVMMGFDGFILTHTMERIEVLEDNEVD 192
Query: 191 EFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGREFGERFG 250
FLPPR+ ++L DF +PIA+G +ATP +Y ++RY+ +A E AK VI+++ E+ G
Sbjct: 193 NFLPPRQ--FNLIDFSDPIAIGPIATPEEYIKYRYEAMKAMERAKGVIEEIMGEYERISG 250
Query: 251 RDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWFRPFPREELL 310
R ++E +DA +VF+ MG+ G K AV+ LR G K G K+R FRPFP+E++
Sbjct: 251 RKQHGLVECYKCEDAKYVFVTMGAWSGDGKAAVDRLRDSGVKTGLLKIRVFRPFPKEKVE 310
Query: 311 EIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIMKNYIVGLGGRDFTVSDVKA 370
E S+KG+ V DR +S+G GIL E K ALY G R + + + G+GG+D +
Sbjct: 311 EYLRSMKGVVVFDRAYSYGYGGILVNEIKAALY--GYRVPVYSVVAGIGGKDVRPRHFQK 368
Query: 371 IAEDM 375
+ ED+
Sbjct: 369 VIEDL 373
>sp|O05651|PORA_THEMA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
SUBUNIT) >gi|7449946|pir||C72427 pyruvate synthase (EC
1.2.7.1) alpha chain - Thermotoga maritima (strain MSB8)
Length = 392
Score = 323 bits (819), Expect = 2e-87
Identities = 171/366 (46%), Positives = 233/366 (62%), Gaps = 3/366 (0%)
Query: 11 VSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMAAC 70
V+G A A A+ VVAAYPITPQT I+E A F+A+G + IPVESEHSAM+A
Sbjct: 10 VTGAEAVANAMRQIEPDVVAAYPITPQTPIVEYFARFVADGVVRTEMIPVESEHSAMSAV 69
Query: 71 IGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQTDSLS 130
+GA+A GAR TATSA GLALMHE+++ AA RLPIVM VNRA++ P ++ D +D+++
Sbjct: 70 VGAAAAGARAMTATSANGLALMHEIVYIAASYRLPIVMPVVNRALSGPINIHCDHSDAMA 129
Query: 131 QRDTGWMQFYAENNQEVYDGVLMAFKVA--ETVNVPAMVVESAFILSHTYEIVNMIPQEL 188
+RD+GW+Q +AE NQE YD ++A ++A E V +P MV FILSH E V P EL
Sbjct: 130 ERDSGWIQLFAETNQEAYDFTILAVRLAEHEDVRLPVMVNLDGFILSHGVEPVEFYPDEL 189
Query: 189 VDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGREFGER 248
V +F+ KP+Y L D E+P+ G L Y+E + + A E KKV ++ +EF E
Sbjct: 190 VKKFVGELKPMYPLLDTEHPVTWGPLDLYDYYFEHKRQQIEAMENVKKVFPEIAKEFEET 249
Query: 249 FGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWFRPFPREE 308
FGR Y +E ++DA+ V + +GS T+K V+ LR++GYKVG K+ FRPFP+E+
Sbjct: 250 FGRKY-WFVEPYRMEDAEHVMVALGSTNSTIKYVVDELREEGYKVGSLKIWMFRPFPKEQ 308
Query: 309 LLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIMKNYIVGLGGRDFTVSDV 368
L E+ K + VLDR SFG E L+ K ALY ARP++ +Y+ GLGGRD +
Sbjct: 309 LQELLNGRKSVVVLDRAVSFGAEAPLYEAVKSALYEVAARPMLGSYVYGLGGRDIKPEHI 368
Query: 369 KAIAED 374
+ ED
Sbjct: 369 RKAFED 374
>emb|CAA59457.1| (X85171) alpha subunit of pyruvate ferredoxin oxidoreductase
[Thermotoga maritima]
>gi|4980501|gb|AAD35111.1|AE001690_5 (AE001690) pyruvate
ferredoxin oxidoreductase, alpha subunit [Thermotoga
maritima]
Length = 394
Score = 323 bits (819), Expect = 2e-87
Identities = 171/366 (46%), Positives = 233/366 (62%), Gaps = 3/366 (0%)
Query: 11 VSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMAAC 70
V+G A A A+ VVAAYPITPQT I+E A F+A+G + IPVESEHSAM+A
Sbjct: 12 VTGAEAVANAMRQIEPDVVAAYPITPQTPIVEYFARFVADGVVRTEMIPVESEHSAMSAV 71
Query: 71 IGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQTDSLS 130
+GA+A GAR TATSA GLALMHE+++ AA RLPIVM VNRA++ P ++ D +D+++
Sbjct: 72 VGAAAAGARAMTATSANGLALMHEIVYIAASYRLPIVMPVVNRALSGPINIHCDHSDAMA 131
Query: 131 QRDTGWMQFYAENNQEVYDGVLMAFKVA--ETVNVPAMVVESAFILSHTYEIVNMIPQEL 188
+RD+GW+Q +AE NQE YD ++A ++A E V +P MV FILSH E V P EL
Sbjct: 132 ERDSGWIQLFAETNQEAYDFTILAVRLAEHEDVRLPVMVNLDGFILSHGVEPVEFYPDEL 191
Query: 189 VDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGREFGER 248
V +F+ KP+Y L D E+P+ G L Y+E + + A E KKV ++ +EF E
Sbjct: 192 VKKFVGELKPMYPLLDTEHPVTWGPLDLYDYYFEHKRQQIEAMENVKKVFPEIAKEFEET 251
Query: 249 FGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWFRPFPREE 308
FGR Y +E ++DA+ V + +GS T+K V+ LR++GYKVG K+ FRPFP+E+
Sbjct: 252 FGRKY-WFVEPYRMEDAEHVMVALGSTNSTIKYVVDELREEGYKVGSLKIWMFRPFPKEQ 310
Query: 309 LLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIMKNYIVGLGGRDFTVSDV 368
L E+ K + VLDR SFG E L+ K ALY ARP++ +Y+ GLGGRD +
Sbjct: 311 LQELLNGRKSVVVLDRAVSFGAEAPLYEAVKSALYEVAARPMLGSYVYGLGGRDIKPEHI 370
Query: 369 KAIAED 374
+ ED
Sbjct: 371 RKAFED 376
>gi|11499291 pyruvate ferredoxin oxidoreductase, subunit alpha (porA)
[Archaeoglobus fulgidus] >gi|7449947|pir||D69462
pyruvate synthase (EC 1.2.7.1) alpha chain -
Archaeoglobus fulgidus >gi|2648853|gb|AAB89548.1|
(AE000986) pyruvate ferredoxin oxidoreductase, subunit
alpha (porA) [Archaeoglobus fulgidus]
Length = 391
Score = 313 bits (794), Expect = 2e-84
Identities = 172/372 (46%), Positives = 237/372 (63%), Gaps = 6/372 (1%)
Query: 7 IKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGE-ADIQYIPVESEHS 65
++KVV G Y+ AY+V + V+ AYPITPQT I+E +A ANGE D +YI ESE
Sbjct: 1 MRKVVRGFYSVAYSVKLCKPNVICAYPITPQTEIVENLAAMYANGELGDAEYITAESEFG 60
Query: 66 AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQ 125
A + +GASA GARVFTAT +QGL LM E+L AAG RLPIV+V+ NRA++ P S+W+D
Sbjct: 61 AASMLVGASAAGARVFTATCSQGLILMSEVLFNAAGMRLPIVLVNTNRALSAPLSIWNDH 120
Query: 126 TDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAET--VNVPAMVVESAFILSHTYEIVNM 183
DS++ RD G MQ Y ENNQE +D + A+KVAE V +P M+ + L+H YE V++
Sbjct: 121 QDSMAMRDAGIMQVYVENNQEAHDMIPQAYKVAENRKVLLPFMICMDGYKLTHAYEPVDL 180
Query: 184 IPQELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGR 243
+ QE VD FLPP +P + + P+A G A P Y EFR + +A E A+K++ DV +
Sbjct: 181 LEQETVDSFLPPYEPAAYMTT-KKPLAFGCYAPPHVYMEFRVAMQQAMERARKIMLDVFK 239
Query: 244 EFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWFRP 303
E+GE GRD+ I + D FV + MGS++G +++ VE LR +G VG K+R FRP
Sbjct: 240 EWGELTGRDWGGHITVDFPDSKIFV-VAMGSVVGLLRKVVEELRGEGLSVGLIKIRTFRP 298
Query: 304 FPREELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIMKNYIVGLGGRDF 363
FP EEL E + + + VLDR+ SFG EG + E K A+Y + + I ++ VGLGGRD
Sbjct: 299 FPVEELREALKDAEKVIVLDRSVSFGYEGPVSIELKSAIYGHSSAEIY-SFAVGLGGRDM 357
Query: 364 TVSDVKAIAEDM 375
++ I D+
Sbjct: 358 PKDFLEKIIRDV 369
>gb|AAK42867.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase
alpha chain) (porA-2) [Sulfolobus solfataricus]
Length = 400
Score = 295 bits (747), Expect = 6e-79
Identities = 164/393 (41%), Positives = 239/393 (60%), Gaps = 13/393 (3%)
Query: 7 IKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSA 66
I+K++SGN A A V ARV V YPITPQT+IIEK+AE A GE + + + VESEHSA
Sbjct: 2 IRKIISGNEAVALGVKLARVGVTGIYPITPQTTIIEKLAEMRAKGEIETEIVRVESEHSA 61
Query: 67 MAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQT 126
MAA GA+ G R FTAT++QGL MHEM+ W AG+R+P+VMV RA+ PW++W++ T
Sbjct: 62 MAATFGAALGGVRAFTATASQGLLYMHEMVWWVAGSRVPVVMVVGTRAVGAPWNIWNEHT 121
Query: 127 DSLSQRDTGWMQFYAENNQEVYDGVLMAFKVA--ETVNVPAMVVESAFILSHTYEIVNMI 184
D S+RD+GW+ +A N QE D L AF+++ E V +P M+ FILSHT V +
Sbjct: 122 DFTSERDSGWIMAFASNPQEALDLTLQAFRISEDERVFLPMMIGMDGFILSHTKTNVLIP 181
Query: 185 PQELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGRE 244
Q+ VD+FLPPR+ Y + D E+P+ +G + P Y R + A ++ VIK++GRE
Sbjct: 182 DQDQVDDFLPPRRQPY-VIDPEDPVGMGNIFPPEGYMRLRESIDLALRNSEDVIKEIGRE 240
Query: 245 FGERFG--RDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWFR 302
+ ++ DYS + ++DAD+ + MG+ G EAV+ LR++G K+G ++R+ R
Sbjct: 241 YNKKINPLGDYSTLNVSYKLEDADYAVVLMGAWAGDAMEAVDTLREKGIKIGMLRIRYLR 300
Query: 303 PFPREELLEIAESVKGIAVLDRNFSFGQ-EGILFTEAKGALYNNGARPIMKNYIVGLGGR 361
P+ +E+ + K + VLDR+ SFG+ G L+ E K + N P +K + GLGG
Sbjct: 301 PWSEKEIRNTLKDKKAVLVLDRSTSFGRGGGPLYVEIKSTISN--VVPQIKGVVSGLGGV 358
Query: 362 DFTVSDVKAIAEDMKKVIESGKLDREVEWYHLK 394
+D+ I K +E L +V WY+ K
Sbjct: 359 TVNKNDLVYI---FNKFVEG--LKDDVIWYYPK 386
>pir||F64658 pyruvate synthase (EC 1.2.7.1) alpha chain - Helicobacter pylori
(strain 26695) >gi|2314261|gb|AAD08154.1| (AE000617)
pyruvate ferredoxin oxidoreductase, alpha subunit
[Helicobacter pylori 26695]
Length = 407
Score = 270 bits (682), Expect = 3e-71
Identities = 147/387 (37%), Positives = 228/387 (57%), Gaps = 5/387 (1%)
Query: 9 KVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMA 68
+V GN A++ A+ A++ V+AAYPITP T I++ F NG D +++ VESEH+AM+
Sbjct: 11 EVWDGNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYVDGEFVLVESEHAAMS 70
Query: 69 ACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQTDS 128
AC+GA+A G RV TATS+QGLALM E+L+ A+G RLPIV+ VNRA+A P ++ D +D
Sbjct: 71 ACVGAAAAGGRVSTATSSQGLALMVEVLYQASGMRLPIVLNLVNRALAAPLNIHGDHSDM 130
Query: 129 LSQRDTGWMQFYAENNQEVYDGVLMAFKVAE--TVNVPAMVVESAFILSHTYEIVNMIPQ 186
RD+GW+ N QE YD LMAF++AE V VP +V + F+ SHT + V +
Sbjct: 131 YLSRDSGWISLCTCNPQEAYDFTLMAFRIAEHQKVRVPTIVNQDGFLCSHTVQNVRPLSD 190
Query: 187 ELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGREFG 246
+ +F+ + +SL DF+ P++ GA A +YE + +L A A VI++V +F
Sbjct: 191 AVAYQFVGEYQTKHSLLDFDKPVSYGAQAEEEWHYEHKAQLHHAIMSASSVIEEVFNDFA 250
Query: 247 ERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWFRPFPR 306
+ GR Y + + ++DA+ +G+ + A + +RK+G K G A + RPFP
Sbjct: 251 KLTGRQY-HLTKTFQLEDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSLRPFPY 309
Query: 307 EELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGA--RPIMKNYIVGLGGRDFT 364
E L + +++K +A+LD++ G G +F E A+Y P++ NYI GLG RD T
Sbjct: 310 ERLGQDLKNLKALAILDKSSPAGTMGAMFNEVTSAVYQTQGTKHPVVSNYIYGLGERDMT 369
Query: 365 VSDVKAIAEDMKKVIESGKLDREVEWY 391
++ + I E++ + G L + +
Sbjct: 370 IAHLCEIFEEINEDALKGTLTHPTQQF 396
>gb|AAC02293.1| (AF013980) pyruvate:ferredoxin oxidoreductase alpha subunit
[Helicobacter pylori]
Length = 396
Score = 269 bits (681), Expect = 3e-71
Identities = 147/377 (38%), Positives = 228/377 (59%), Gaps = 6/377 (1%)
Query: 9 KVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMA 68
+V GN A++ A+ A++ V+AAYPITP T I++ F NG D +++ VESEH+AM+
Sbjct: 11 EVWDGNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYIDGEFVLVESEHAAMS 70
Query: 69 ACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQTDS 128
AC+GA+A G RV TATS+QGLALM E+L+ A+G RLPIV+ VNRA+A P ++ D +D
Sbjct: 71 ACVGAAAAGGRVSTATSSQGLALMVEVLYQASGMRLPIVLNLVNRALAAPLNIHGDHSDM 130
Query: 129 LSQRDTGWMQFYAENNQEVYDGVLMAFKVAE--TVNVPAMVVESAFILSHTYEIVNMIPQ 186
RD+GW+ N QE YD LMAFK+AE V VP +V + F+ SHT + V +
Sbjct: 131 YLSRDSGWISLCTCNPQEAYDFTLMAFKIAEHQKVRVPTIVNQDGFLCSHTVQNVRPLSD 190
Query: 187 ELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGREFG 246
+ +F+ + +SL DF+ P++ GA A +YE + +L A A VI++V +F
Sbjct: 191 AVAYQFVGEYQTKHSLLDFDKPVSYGAQAEEEWHYEHKAQLHHAIMSASSVIEEVFNDFA 250
Query: 247 ERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWFRPFPR 306
+ GR Y + + ++DA+ +G+ + A + +RK+G K G A + RPFP
Sbjct: 251 KLTGRQY-HLTKTFQLEDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSLRPFPY 309
Query: 307 EELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGA--RPIMKNYIVGLGGRDFT 364
E+L + +++K +A+LD++ G G +F E A+Y P++ NYI GLG RD T
Sbjct: 310 EKLGQDLKNLKALAILDKSSPAGAMGAMFNEVTSAVYQTQGTKHPVVSNYIYGLGERDMT 369
Query: 365 VSDV-KAIAEDMKKVIE 380
++ + K + + MK +++
Sbjct: 370 IAHLWKFLKKSMKTLLK 386
>pir||H71857 pyruvate ferrodoxin oxidoreductase - Helicobacter pylori (strain
J99) >gi|4155626|gb|AAD06616.1| (AE001531) Pyruvate
ferrodoxin oxidoreductase [Helicobacter pylori J99]
Length = 407
Score = 268 bits (679), Expect = 6e-71
Identities = 147/387 (37%), Positives = 227/387 (57%), Gaps = 5/387 (1%)
Query: 9 KVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMA 68
+V GN A++ A+ A++ V+AAYPITP T I++ F NG D +++ VESEH+AM+
Sbjct: 11 EVWDGNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYVDGEFVLVESEHAAMS 70
Query: 69 ACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQTDS 128
AC+GA+A G RV TATS+QGLALM E+L+ A+G RLPIV+ VNRA+A P ++ D +D
Sbjct: 71 ACVGAAAAGGRVSTATSSQGLALMVEVLYQASGMRLPIVLNLVNRALAAPLNIHGDHSDM 130
Query: 129 LSQRDTGWMQFYAENNQEVYDGVLMAFKVAE--TVNVPAMVVESAFILSHTYEIVNMIPQ 186
RD+GW+ N QE YD LMAF++AE V VP +V + F+ SHT + V +
Sbjct: 131 YLSRDSGWISLCTCNPQEAYDFTLMAFRIAEHQKVRVPTIVNQDGFLCSHTVQNVRPLSD 190
Query: 187 ELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGREFG 246
+ +F+ + +SL DF+ P++ GA A +YE + +L A A VI++V +F
Sbjct: 191 AVAYQFVGEYQTKHSLLDFDKPVSYGAQAEEEWHYEHKAQLHHAIMSASSVIEEVFNDFA 250
Query: 247 ERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWFRPFPR 306
+ GR Y + + ++DA+ +G+ + A + +RK+G K G A + RPFP
Sbjct: 251 KLTGRQY-HLTKTFQLEDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSLRPFPY 309
Query: 307 EELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGA--RPIMKNYIVGLGGRDFT 364
E L + +++K +A+LD++ G G +F E A+Y P++ NYI GLG RD T
Sbjct: 310 ERLGQDLKNLKALAILDKSSPAGAMGAMFNEVTSAVYQTQGTKHPVVSNYIYGLGERDMT 369
Query: 365 VSDVKAIAEDMKKVIESGKLDREVEWY 391
+ + I E++ + G L + +
Sbjct: 370 IVHLCEIFEEINEDALKGTLTHPTQQF 396
>gi|11499635 2-ketoisovalerate ferredoxin oxidoreductase, subunit alpha (vorA)
[Archaeoglobus fulgidus] >gi|7449955|pir||D69506
probable 2-oxoisovalerate--ferredoxin oxidoreductase (EC
1.2.7.-) alpha chain AF2053 [similarity] - Archaeoglobus
fulgidus >gi|2648476|gb|AAB89196.1| (AE000961)
2-ketoisovalerate ferredoxin oxidoreductase, subunit
alpha (vorA) [Archaeoglobus fulgidus]
Length = 366
Score = 246 bits (621), Expect = 4e-64
Identities = 146/384 (38%), Positives = 222/384 (57%), Gaps = 32/384 (8%)
Query: 7 IKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSA 66
+KK+++ N A A AV A+ V+AAYPITPQ+ I+EK++E + +GE D +++ VESEHSA
Sbjct: 13 MKKLLTSNEAIAEAVKLAKPDVIAAYPITPQSPIVEKLSEMVDSGELDSRFVRVESEHSA 72
Query: 67 MAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQT 126
M IGA+ GARVFTATS+ GLA M+EM WAAG+RLPIVM R++ PW++ D
Sbjct: 73 MGVVIGAATAGARVFTATSSHGLAYMYEMCWWAAGSRLPIVMALAARSIGAPWNIHGDHL 132
Query: 127 DSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNMIPQ 186
D ++ RD GW+ AEN QE +D L AF ++E VN+P V F +SHT E+V
Sbjct: 133 DLMAMRDLGWIISVAENAQEAFDMTLNAFMLSEEVNIPVAVAIDGFTMSHTAEVV----- 187
Query: 187 ELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGREFG 246
E+ + +PPRK Y + + +A+ A+ RY LA+ E + ++I+
Sbjct: 188 EVREVEIPPRKQAYRILPGMD-VALNAVTFGEARMTARYDLAKDLENSAELIE------- 239
Query: 247 ERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWFRPFPR 306
++Y ++E+ ++DAD+ + G L G VK+AV++LR++G K+G ++++ RPFP+
Sbjct: 240 ----KEYGGLVERYRLEDADYAVVVTGGLSGDVKDAVDMLREEGVKMGVLRLKFIRPFPK 295
Query: 307 EELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIMKNYIVGLGGRDFTVS 366
+ + + V V+DR + G L E N N + G+GGR TV
Sbjct: 296 KAVKSLPSQV---LVVDR-ANTDLRGTLSVEVAACGVEN------VNVVAGIGGRYPTVE 345
Query: 367 DVKAIAEDMKKVIESGKLDREVEW 390
++ + K GKL +VEW
Sbjct: 346 ELYSCL----KRFADGKLS-DVEW 364
>gb|AAK42308.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase
alpha chain) (porA-like) [Sulfolobus solfataricus]
Length = 415
Score = 237 bits (599), Expect = 1e-61
Identities = 132/377 (35%), Positives = 209/377 (55%), Gaps = 15/377 (3%)
Query: 10 VVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMAA 69
+++G A A+A ++A V VVAAYPI P T +++ I++ IA+GE D ++I E EH
Sbjct: 13 LMNGTQAVAHAAMYADVDVVAAYPIRPYTEVMDTISKLIADGELDAEFIVAEGEHGQFET 72
Query: 70 CIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQTDSL 129
AS GAR +S G E + A R P+V + NRA+ P + + D+L
Sbjct: 73 VKHASLAGARTLVGSSGVGWLYAMEAIVVTATDRAPVVAIIGNRALDDPGAYGVEHNDAL 132
Query: 130 SQRDTGWMQFYAENNQEVYDGVLMAFKVAE--TVNVPAMVVESAFILSHTYEIVNMIPQE 187
RD GW+ + + QE +D L+A+++AE V +P + L+H+ +IV + P+E
Sbjct: 133 MVRDVGWLLVWVDTAQEAFDTALLAYRIAEDQRVLLPLGISMDGGFLTHSEQIVRLPPRE 192
Query: 188 LVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGREFGE 247
LV FLPP L +NPI V E R + A E A+ VI + EF +
Sbjct: 193 LVKNFLPPYNRGKYLVHPDNPITVAPQVNEDWVMEIRRQHEEAMERARSVIVEAYEEFKK 252
Query: 248 RFGR----------DYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAK 297
FGR + +E IDDA+ V +GMG++ +K A++ +R+QGYKVG +
Sbjct: 253 VFGRYPGSTSDLQMPENPFVEPYMIDDAEVVLIGMGTVSKPMKVAIKNMRRQGYKVGMLR 312
Query: 298 VRWFRPFPREELLEIAESVKGIAVLDRNFSFG---QEGILFTEAKGALYNNGARPIMKNY 354
+RWFRPFP ++++ + + + V+DR++S G + G+++ E + +LY+ RP + N+
Sbjct: 313 IRWFRPFPTQDVIRYLANSRVVCVIDRDYSMGSPNRGGVIYHEVRSSLYDLDQRPRVMNF 372
Query: 355 IVGLGGRDFTVSDVKAI 371
I GLGGR+ T+ DV+ I
Sbjct: 373 IGGLGGREITIQDVEKI 389
>pir||S74041 pyruvate synthase (EC 1.2.7.1) alpha chain - Sulfolobus
solfataricus >gi|1707735|emb|CAA69455.1| (Y08256)
pyruvate-ferredoxin oxidoreductase alpha-2 [Sulfolobus
solfataricus]
Length = 415
Score = 237 bits (599), Expect = 1e-61
Identities = 132/377 (35%), Positives = 209/377 (55%), Gaps = 15/377 (3%)
Query: 10 VVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMAA 69
+++G A A+A ++A V VVAAYPI P T +++ I++ IA+GE D ++I E EH
Sbjct: 13 LMNGTQAVAHAAMYADVDVVAAYPIRPYTEVMDTISKLIADGELDAEFIVAEGEHGQFET 72
Query: 70 CIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQTDSL 129
AS GAR +S G E + A R P+V + NRA+ P + + D+L
Sbjct: 73 VKHASLAGARTLVGSSGVGWLYAMEAIVVTATDRAPVVAIIGNRALDDPGAYGVEHNDAL 132
Query: 130 SQRDTGWMQFYAENNQEVYDGVLMAFKVAE--TVNVPAMVVESAFILSHTYEIVNMIPQE 187
RD GW+ + + QE +D L+A+++AE V +P + L+H+ +IV + P+E
Sbjct: 133 MVRDVGWLLVWVDTAQEAFDTALLAYRIAEDQRVLLPLGISMDGGFLTHSEQIVRLPPRE 192
Query: 188 LVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGREFGE 247
LV FLPP L +NPI V E R + A E A+ VI + EF +
Sbjct: 193 LVKNFLPPYNRGKYLVHPDNPITVAPQVNEDWVMEIRRQHEEAMERARSVIVEAYEEFKK 252
Query: 248 RFGR----------DYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAK 297
FGR + +E IDDA+ V +GMG++ +K A++ +R+QGYKVG +
Sbjct: 253 VFGRYPGSTSDLQMPENPFVEPYMIDDAEVVLIGMGTVSKPMKVAIKNMRRQGYKVGMLR 312
Query: 298 VRWFRPFPREELLEIAESVKGIAVLDRNFSFG---QEGILFTEAKGALYNNGARPIMKNY 354
+RWFRPFP ++++ + + + V+DR++S G + G+++ E + +LY+ RP + N+
Sbjct: 313 IRWFRPFPTQDVIRYLANSRVVCVIDRDYSMGSPNRGGVIYHEVRSSLYDLDQRPRVMNF 372
Query: 355 IVGLGGRDFTVSDVKAI 371
I GLGGR+ T+ DV+ I
Sbjct: 373 IGGLGGREITIQDVEKI 389
>gb|AAC38206.1| (AF021092) PorA subunit of pyruvate:flavodoxin oxidoreductase
[Helicobacter pylori]
Length = 408
Score = 226 bits (569), Expect = 5e-58
Identities = 133/388 (34%), Positives = 208/388 (53%), Gaps = 6/388 (1%)
Query: 9 KVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMA 68
+V GN A++ A+ A++ V+AAYPITP T I++ F NG D + VESEH+AM+
Sbjct: 11 EVWDGNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYIDGDFALVESEHAAMS 70
Query: 69 ACIGASATGARVFTATSAQGLALM-HEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQTD 127
AC+GA+A G RV TATS+QG + + +G R IV VNRA+A P ++ D +D
Sbjct: 71 ACVGAAAAGGRVSTATSSQGSGVNGRGFITKVSGMRSAIVGNLVNRALAAPLNIHGDHSD 130
Query: 128 SLSQRDTGWMQFYAENNQEVYDGVLMAFKVAE--TVNVPAMVVESAFILSHTYEIVNMIP 185
RD+GW+ N QE YD LMAFK+ E V VP +V + F+ SHT + V +
Sbjct: 131 MYLSRDSGWISLCTCNPQEAYDFTLMAFKLGEHQKVRVPTIVNQDGFLCSHTVQNVRPLS 190
Query: 186 QELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGREF 245
+ +F+ + +SL DF+ P++ GA A +YE + +L A A VI++V +F
Sbjct: 191 DGVAYQFVGEYQTKHSLVDFDKPVSYGAQAEEEWHYEHKARLHHAIMSASSVIEEVFNDF 250
Query: 246 GERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWFRPFP 305
+ GR Y + + ++DA+ +G+ + A + +RK+G K G A + P
Sbjct: 251 AKLTGRQY-HLTKTFQLEDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSCAPSL 309
Query: 306 REELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGA--RPIMKNYIVGLGGRDF 363
L +++K +A+LD+ G G +F E +Y P++ NYI GLG RD
Sbjct: 310 MRRLGRDLKNLKALAILDKRSPAGAMGAMFNEVTSTVYQTQGTKHPVVSNYIYGLGERDM 369
Query: 364 TVSDVKAIAEDMKKVIESGKLDREVEWY 391
T++ + I E++ + G L + +
Sbjct: 370 TIAHLCEIFEEINEDALKGTLTHPTQQF 397
>gb|AAD55756.1|AF132673_1 (AF132673) pyruvate:ferredoxin oxidoreductase [Clostridium
pasteurianum]
Length = 1098
Score = 145 bits (362), Expect = 9e-34
Identities = 111/383 (28%), Positives = 187/383 (47%), Gaps = 21/383 (5%)
Query: 9 KVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADI-----QYIPVESE 63
K + GN AAAYA +A +V A YPITP T + E + E+ A+ + ++ + ++SE
Sbjct: 4 KTMDGNEAAAYAS-YAFTEVAAIYPITPSTPMAESVDEWSAHDKKNVFDQAVNVVEMQSE 62
Query: 64 HSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAP-PWSVW 122
A + G+ A GA T T++QGL LM ++ AG +LP V RA+A S++
Sbjct: 63 AGAAGSVHGSLAAGALTTTYTASQGLLLMIPNMYKIAGEQLPTVFHVSARAIATHALSIF 122
Query: 123 DDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVN 182
D D ++ R TG+ + + QE D ++ VP + F SH + +
Sbjct: 123 GDHQDVMACRQTGFALLASSSVQEAMDLGCISHLSTIKSKVPFLHFFDGFRTSHEIQKIE 182
Query: 183 MIPQELVDEFLPPRKPLYSLADFEN-------PIAVGALATPADYYEFRYKLARAHEEAK 235
+I E L P + ++ F N P+ G P Y++ R + +
Sbjct: 183 VIDYE----DLRPLVDIDAVKAFRNNALNPEHPVTRGTAENPDVYFQGREASNKYYNAIP 238
Query: 236 KVIKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGY 295
+++++ E + GR+Y + +DA+ + + MGS+ ++E ++ L +G KVG
Sbjct: 239 ELVENYMGEISKITGREY-HLFNYYGAEDAERIIIAMGSISDAIEETIDYLNAKGEKVGV 297
Query: 296 AKVRWFRPFPREELLE-IAESVKGIAVLDRNFSFGQEG-ILFTEAKGALYNNGARPIMKN 353
KV FRPF E + I ++VK IAVLDR G G L+ + A Y + P++
Sbjct: 298 LKVHLFRPFSVEHFFKYIPKTVKKIAVLDRTKEPGSYGEPLYLDVVTAFYQSDLNPVIVG 357
Query: 354 YIVGLGGRDFTVSDVKAIAEDMK 376
GLG + ++ SD+ A+ +++K
Sbjct: 358 GRYGLGSKRYSSSDILAVYDNLK 380
>emb|CAB43935.1| (Y17727) pyruvate ferredoxin oxidoreductase [Clostridium
pasteurianum]
Length = 1175
Score = 142 bits (354), Expect = 8e-33
Identities = 111/383 (28%), Positives = 183/383 (46%), Gaps = 21/383 (5%)
Query: 9 KVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEAD-----IQYIPVESE 63
K + GN AAA+ + +A V A YPITP + + E + E+ G + ++ + ++SE
Sbjct: 5 KTMDGNTAAAH-IAYAFTDVTAIYPITPSSPMAEHVDEWAVQGRKNLFGQTVKVMEMQSE 63
Query: 64 HSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPP-WSVW 122
A A G+ GA T T++QGL LM ++ AG LP V RA+A +++
Sbjct: 64 AGAAGAVHGSLQAGALTTTFTASQGLLLMIPNMYKIAGELLPGVFHVSARALATKSLNIF 123
Query: 123 DDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVN 182
D D ++ R TG+ + QEV D +A A VP + F SH + +
Sbjct: 124 GDHQDVMAARQTGFALLAEGSVQEVMDLSAVAHLAAIKGKVPFLNFFDGFRTSHEIQKIE 183
Query: 183 MIPQELVDEFLPPRKPLYSLADFEN-------PIAVGALATPADYYEFRYKLARAHEEAK 235
+I E L P + ++ F N P+ G P Y++ R + +
Sbjct: 184 VIDYE----DLRPLVDIDAVKAFRNNALNPEHPVTRGTAENPDVYFQGREASNKYYNAIP 239
Query: 236 KVIKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGY 295
+++++ E + GR+Y + +DA+ + + MGS+ ++E ++ L +G KVG
Sbjct: 240 ELVENYMGEISKITGREY-HLFNYYGAEDAERIIIAMGSISDAIEETIDYLNAKGEKVGV 298
Query: 296 AKVRWFRPFPREELLE-IAESVKGIAVLDRNFSFGQEG-ILFTEAKGALYNNGARPIMKN 353
KV FRPF E + I ++VK IAVLDR G G L+ + A Y + P++
Sbjct: 299 LKVHLFRPFSVEHFFKYIPKTVKKIAVLDRTKEPGSYGEPLYLDVVTAFYQSDLNPVIVG 358
Query: 354 YIVGLGGRDFTVSDVKAIAEDMK 376
GLG +D SD+ A+ +++K
Sbjct: 359 GRYGLGSKDTVPSDILAVYDNLK 381
>emb|CAB43933.1| (Y17726) pyruvate ferredoxin oxidoreductase [Clostridium
pasteurianum]
Length = 1175
Score = 141 bits (352), Expect = 1e-32
Identities = 110/385 (28%), Positives = 186/385 (47%), Gaps = 21/385 (5%)
Query: 7 IKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADI-----QYIPVE 61
I K + GN AAAYA +A +V A YPITP T + E + E+ A+ + +I + ++
Sbjct: 4 IMKTMDGNEAAAYAS-YAFTEVAAIYPITPSTPMAESVDEWSAHDKKNIFDQAVNVVEMQ 62
Query: 62 SEHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAP-PWS 120
SE A + G+ A GA T T++QGL LM ++ AG +LP V RA+A S
Sbjct: 63 SEAGAAGSVHGSLAAGALTTTYTASQGLLLMIPNMYKIAGEQLPTVFHVSARAIATHALS 122
Query: 121 VWDDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEI 180
++ D D ++ R TG+ + + QE D ++ VP + F SH Y+
Sbjct: 123 IFGDHQDVMACRQTGFALLASSSVQEAMDLGCISHLSTIKSKVPFLHFFDGFRTSHEYQK 182
Query: 181 VNMIPQELVDEFLPPRKPLYSLADF-------ENPIAVGALATPADYYEFRYKLARAHEE 233
+ +I E + + S+ +F E+P+ G P Y++ R + ++
Sbjct: 183 IEIIDYEDLKNLVDYN----SIKEFRDKALNPEHPVVRGTAQNPDIYFQGREASNKFYDA 238
Query: 234 AKKVIKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKV 293
++++ +E GR+Y + DA+ + + MGS+ T+ E+++ LR +G KV
Sbjct: 239 VPDIVENYMKEIKSITGREYHPF-DYYGAPDAENIIIAMGSVCDTIDESIDYLRNKGEKV 297
Query: 294 GYAKVRWFRPFPREELLEI-AESVKGIAVLDRNFSFGQ-EGILFTEAKGALYNNGARPIM 351
G KV +RPF + + ++VK IAVLDR G L+ + N+ +PI+
Sbjct: 298 GVIKVHLYRPFSSKYFFNVFPKTVKKIAVLDRTKEPGSLAEPLYLDVVHLFNNSAEKPII 357
Query: 352 KNYIVGLGGRDFTVSDVKAIAEDMK 376
GLG +D S + ++ ++K
Sbjct: 358 IGGRYGLGSKDTRPSQILSVFNNLK 382
>sp|P03833|NIFJ_KLEPN PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|43821|emb|CAA31665.1|
(X13303) nifJ protein (AA 1-1171) [Klebsiella
pneumoniae]
Length = 1171
Score = 140 bits (349), Expect = 3e-32
Identities = 114/381 (29%), Positives = 180/381 (46%), Gaps = 15/381 (3%)
Query: 9 KVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPV-----ESE 63
K + GN AAA+ + +A +V A YPITP T + E + E+ A G+ ++ PV +SE
Sbjct: 6 KTMDGNAAAAW-ISYAFTEVAAIYPITPSTPMAENVDEWAAQGKKNLFGQPVRLMEMQSE 64
Query: 64 HSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAP-PWSVW 122
A A GA GA T T++QGL LM ++ AG LP V RA+A +++
Sbjct: 65 AGAAGAVHGALQAGALTTTYTASQGLLLMIPNMYKIAGELLPGVFHVSARALATNSLNIF 124
Query: 123 DDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVN 182
D D ++ R TG N Q+V D +A A +P + F SH + +
Sbjct: 125 GDHQDVMAVRQTGCAMLAENNVQQVMDLSAVAHLAAIKGRIPFVNFFDGFRTSHEIQKIE 184
Query: 183 MIPQELVDEFLPPRKPLYSLADF----ENPIAVGALATPADYYEFRYKLARAHEEAKKVI 238
++ E + L R L S ++P+ G P Y++ R R ++ ++
Sbjct: 185 VLEYEQLATLLD-RPALDSFRRNALHPDHPVIRGTAQNPDIYFQEREAGNRFYQALPDIV 243
Query: 239 KDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKV 298
+ + GR+Y + DA+ V + MGS+ TV+E V+ L G KVG V
Sbjct: 244 ESYMTQISALTGREY-HLFNYTGAADAERVIIAMGSVCDTVQEVVDTLNAAGEKVGLLSV 302
Query: 299 RWFRPFPREELL-EIAESVKGIAVLDRNFSFG-QEGILFTEAKGALYNNGARPIMKNYIV 356
FRPF ++ ++V+ IAVLDR G Q L + K A Y++ P++
Sbjct: 303 HLFRPFSLAHFFAQLPKTVQRIAVLDRTKEPGAQAEPLCLDVKNAFYHHDDAPLIVGGRY 362
Query: 357 GLGGRDFTVSDVKAIAEDMKK 377
LGG+D +D+ A+ +++ K
Sbjct: 363 ALGGKDVLPNDIAAVFDNLNK 383
>pir||QQKBFP pyruvate (flavodoxin) dehydrogenase nifJ (EC 1.2.99.-) - Klebsiella
pneumoniae >gi|43863|emb|CAA31501.1| (X13109)
pyruvate-flavodoxin oxidoreductase [Klebsiella
pneumoniae]
Length = 1171
Score = 140 bits (349), Expect = 3e-32
Identities = 114/381 (29%), Positives = 180/381 (46%), Gaps = 15/381 (3%)
Query: 9 KVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPV-----ESE 63
K + GN AAA+ + +A +V A YPITP T + E + E+ A G+ ++ PV +SE
Sbjct: 6 KTMDGNAAAAW-ISYAFTEVAAIYPITPSTPMAENVDEWAAQGKKNLFGQPVRLMEMQSE 64
Query: 64 HSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAP-PWSVW 122
A A GA GA T T++QGL LM ++ AG LP V RA+A +++
Sbjct: 65 AGAAGAVHGALQAGALTTTYTASQGLLLMIPNMYKIAGELLPGVFHVSARALATNSLNIF 124
Query: 123 DDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVN 182
D D ++ R TG N Q+V D +A A +P + F SH + +
Sbjct: 125 GDHQDVMAVRQTGCAMLAENNVQQVMDLSAVAHLAAIKGRIPFVNFFDGFRTSHEIQKIE 184
Query: 183 MIPQELVDEFLPPRKPLYSLADF----ENPIAVGALATPADYYEFRYKLARAHEEAKKVI 238
++ E + L R L S ++P+ G P Y++ R R ++ ++
Sbjct: 185 VLEYEQLATLLD-RPALDSFRRNALHPDHPVIRGTAQNPDIYFQEREAGNRFYQALPDIV 243
Query: 239 KDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKV 298
+ + GR+Y + DA+ V + MGS+ TV+E V+ L G KVG V
Sbjct: 244 ESYMTQISALTGREY-HLFNYTGAADAERVIIAMGSVCDTVQEVVDTLNAAGEKVGLLSV 302
Query: 299 RWFRPFPREELL-EIAESVKGIAVLDRNFSFG-QEGILFTEAKGALYNNGARPIMKNYIV 356
FRPF ++ ++V+ IAVLDR G Q L + K A Y++ P++
Sbjct: 303 HLFRPFSLAHFFAQLPKTVQRIAVLDRTKEPGAQAEPLCLDVKNAFYHHDDAPLIVGGRY 362
Query: 357 GLGGRDFTVSDVKAIAEDMKK 377
LGG+D +D+ A+ +++ K
Sbjct: 363 ALGGKDVLPNDIAAVFDNLNK 383
>sp|P19543|NIFJ_ENTAG PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|469077|emb|CAA55302.1|
(X78558) nifJ [Pantoea agglomerans]
>gi|1480137|emb|CAA68011.1| (X99694) nifJ [Enterobacter
agglomerans]
Length = 1173
Score = 139 bits (348), Expect = 4e-32
Identities = 112/379 (29%), Positives = 180/379 (46%), Gaps = 15/379 (3%)
Query: 9 KVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEAD-----IQYIPVESE 63
K + GN AAAY V +A V A YPITP T + E + E+ A G+ + ++ + ++SE
Sbjct: 6 KTMDGNTAAAY-VSYAFTDVTAIYPITPSTPMAESVDEWAAQGKKNLFGQTVKIMEMQSE 64
Query: 64 HSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAP-PWSVW 122
A A GA GA T T++QGL LM ++ AG LP V RA+A +++
Sbjct: 65 SGAAGAIHGALQAGALATTYTASQGLLLMTPNMYKIAGELLPAVFHVSARALATNSLNIF 124
Query: 123 DDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVN 182
D DS + R TG + Q+V D +A A +P + F SH + +
Sbjct: 125 GDHQDSYAVRHTGCAMLAESSVQQVMDLAAVAHLTAIKGRIPFINFFDGFRTSHEIQKIE 184
Query: 183 MIPQE----LVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVI 238
++ E L+D R +L ++P+ G P Y++ R + + +++
Sbjct: 185 VLDYEDLAHLLDRDAVARFRQNALHP-DHPVVRGTAQNPDIYFQEREASNKFYMALPEMV 243
Query: 239 KDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKV 298
+ + GR+Y + DA + + MGS+ T++E V+ L +G KVG V
Sbjct: 244 ESYMAKISALTGREY-HLFNYYGAPDAGRMIIAMGSVCETIQETVDYLNARGEKVGVLTV 302
Query: 299 RWFRPFPREELLE-IAESVKGIAVLDRNFSFGQ-EGILFTEAKGALYNNGARPIMKNYIV 356
+RPF + + I +SV IAVLDR G L+ + K A YN+ RP++
Sbjct: 303 HLYRPFSLKHFFKYIPKSVSNIAVLDRTKEPGSLAEPLYLDVKSAFYNSDWRPVIVGGRY 362
Query: 357 GLGGRDFTVSDVKAIAEDM 375
LGG+D S + +I +++
Sbjct: 363 ALGGKDILPSHIISIFDNL 381
>dbj|BAA95605.1| (AB042412) pyruvate:ferredoxin oxidoreductase alpha subunit
[Hydrogenobacter thermophilus]
Length = 400
Score = 139 bits (347), Expect = 5e-32
Identities = 109/358 (30%), Positives = 160/358 (44%), Gaps = 33/358 (9%)
Query: 8 KKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAM 67
K ++G+ A AV A V +YPITPQ+ I E G + Y ESE M
Sbjct: 30 KHFMTGSEAVKEAVKRASVDASVSYPITPQSEAAHLIGELWVEGYVGV-YFRGESEFGVM 88
Query: 68 AACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQTD 127
+ G + GAR T TS G E AG R+P+ +V + R + P S+ D +
Sbjct: 89 SEIAGCALAGARTITTTSGPGTLRAMENFPMWAGTRIPVQLVLMARGVNAPLSIQPDNLE 148
Query: 128 SLSQRDTGWMQFYAENNQEVYDGVLMAFKVAE--TVNVPAMVVESAFILSHTYEIVNMIP 185
DTG M +YAE Q+++D +L F VAE V+VP + V F +SHT E V + P
Sbjct: 149 VSFLLDTGCMIWYAETAQDLFDMILAGFVVAEQPDVHVPVITVVDGFFVSHTRETVMLPP 208
Query: 186 QELVDEFLPPRKPLYS---LADFENP---------IAVGALATPADYYEFRYKLARAHEE 233
++ LPP P + + D E P + + A + +++++ A E
Sbjct: 209 DDIA---LPPYNPYRAPMPVIDAEVPPGRFLRDPFVMKSNYISYATHASWQWEVRAAIER 265
Query: 234 AKKVIKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKV 293
++ K R E FG +AD VF+ G+ KEAV +L +G
Sbjct: 266 SRPYAKHYLRGLIEHFGD-----------PEADLVFVACGTASAQAKEAVRMLEDEGISA 314
Query: 294 GYAKVRWFRPFPREELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIM 351
K++ RPFP EEL E + K I V + F G L E + LY + + I+
Sbjct: 315 RVVKLKTIRPFPIEELREATKGAKYIFVPE----FNVVGWLEREVRRYLYGHSSAEII 368
>gb|AAC83148.1| (AF061850) putative pyruvate oxidoreductase; POR [Brachyspira
pilosicoli]
Length = 275
Score = 139 bits (347), Expect = 5e-32
Identities = 88/261 (33%), Positives = 132/261 (49%), Gaps = 5/261 (1%)
Query: 49 ANGEADIQYIPVESEHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVM 108
ANG + IP + EH A C GA+ G RVF ATSA GL E L AG R P+V+
Sbjct: 3 ANGRHTVCMIPGDGEHGAAGICYGATTAGGRVFNATSANGLLFAMEQLPVQAGTRFPMVL 62
Query: 109 VDVNRAMAPPWSVWDDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVV 168
VNR ++ P + DQ+D + +TGW+ A Q VYD + A K+AE +P +V
Sbjct: 63 NVVNRTVSGPLDIKCDQSDIMMALNTGWIIIMAHTTQMVYDFNIFALKIAEKAKLPIIVS 122
Query: 169 ESAFILSHTYEIVNMIPQEL-VDEFLPPRKP-LYSLADFENPIAVGALATPADYYEFRYK 226
F SH + +++ + V +FL P + S+ +NP+ +G + + +
Sbjct: 123 SDGFFTSHQKKKIHLFKNDKDVQDFLGKYTPEVTSVEPTKNPVTIGPYMNEDELTGSKLQ 182
Query: 227 LARAHEEAKKVIKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELL 286
L++A E+++ +I +V EF GR YS IE ++ A+ M GS T AV+ +
Sbjct: 183 LSQALEDSRAIIAEVFEEFASLSGRKYSP-IETHNMEGAEVALMLCGSAYETGTLAVDEM 241
Query: 287 RK--QGYKVGYAKVRWFRPFP 305
RK K+G + RPFP
Sbjct: 242 RKANPNLKIGAFAITQIRPFP 262
>pir||F82447 pyruvate-flavoredoxin oxidoreductase VCA0530 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9657937|gb|AAF96433.1| (AE004384)
pyruvate-flavoredoxin oxidoreductase [Vibrio cholerae]
Length = 1079
Score = 138 bits (344), Expect = 1e-31
Identities = 111/378 (29%), Positives = 182/378 (47%), Gaps = 22/378 (5%)
Query: 10 VVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADI-----QYIPVESEH 64
+ N A A V + +V+A YPITP TS+ E ++ + ++++ + + ++SE
Sbjct: 4 ITDANTAVA-RVAYQLSEVLAVYPITPSTSMAESCEQWASQQKSNLLGDVPKLVEMQSEA 62
Query: 65 SAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAP-PWSVWD 123
++A GA+ +GA T TS+QGL LM L+ AG P V+ R +A S++
Sbjct: 63 GSIAVVHGAAMSGALATTFTSSQGLLLMIPSLYKLAGELTPCVIHVAARTVATHALSIYC 122
Query: 124 DQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNM 183
D +D ++ R TG A N QE D +A A +P + F+ SH +
Sbjct: 123 DHSDVMAIRQTGVAMLCASNAQEAQDLAAIATFSALQCRLPFVHFFDGFLTSHAITQIEP 182
Query: 184 IPQELVDEFLPPRKPLYSLADF-------ENPIAVGALATPADYYEFRYKLARAHEEAKK 236
+ +E + LP + +L DF + P GA A P Y++ R H+ +
Sbjct: 183 LSEEALSALLP----MPALVDFRTRVLTPDRPTLRGATADPDSYFQCREAQTPYHQSTPE 238
Query: 237 VIKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYA 296
++++ F + GR Y ++ E A V + MGS + T+K+ V +QG ++G
Sbjct: 239 QVQNIMDCFETQTGRRY-QLAEYIGHPQAQSVIVAMGSSVDTIKQVVLAGVQQGERIGVI 297
Query: 297 KVRWFRPFPREELLE-IAESVKGIAVLDRNFSFGQEG-ILFTEAKGALYNNGARPI-MKN 353
++R +RPFP + L + + +V I+VLDR G G L+ + ALY A I +
Sbjct: 298 QIRLYRPFPSQALRDALPATVTHISVLDRTKEPGSHGEPLYLDVLSALYTQRANSIRLSR 357
Query: 354 YIVGLGGRDFTVSDVKAI 371
GL G+ F DV+AI
Sbjct: 358 GRYGLSGKAFYPEDVEAI 375
>pir||B70400 ferredoxin oxidoreductase alpha subunit - Aquifex aeolicus
>gi|2983615|gb|AAC07184.1| (AE000726) ferredoxin
oxidoreductase alpha subunit [Aquifex aeolicus]
Length = 389
Score = 136 bits (339), Expect = 4e-31
Identities = 105/344 (30%), Positives = 159/344 (45%), Gaps = 16/344 (4%)
Query: 8 KKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAM 67
KK ++G+ A A AV A V V AYPITPQ+ + + + A G Y E E+ AM
Sbjct: 20 KKFITGSQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVK-DYYRAEEEYGAM 78
Query: 68 AACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQTD 127
+A GA GAR FTATS GL E + G R+P V+ + R + P S+ D +
Sbjct: 79 SAIAGAVRGGARAFTATSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVE 138
Query: 128 SLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNV--PAMVVESAFILSHTYEIVNMIP 185
++G + +AEN Q+V+D L F ++E V+V P +V F ++H V + P
Sbjct: 139 ISYLLNSGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELPP 198
Query: 186 QELVDEFLPPRKPLYS---LADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVG 242
+++ LPPR P + D E P A P F L H ++ +
Sbjct: 199 EDMK---LPPRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYL--IHAVWQQEVWSAN 253
Query: 243 REFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWFR 302
R ++ + Y + + DA+ + G +EA +G VG KV+ R
Sbjct: 254 RR-AAKWIKHYLGGLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIKVKSLR 312
Query: 303 PFPREELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNG 346
PFP +E+ E ++ K + V + N G L E K A+ N+G
Sbjct: 313 PFPVDEIREALKNAKAVIVPEHNI----VGWLAKEVKAAIPNSG 352
>pir||C70403 ferredoxin oxidoreductase alpha subunit - Aquifex aeolicus
>gi|2983644|gb|AAC07211.1| (AE000728) ferredoxin
oxidoreductase alpha subunit [Aquifex aeolicus]
Length = 404
Score = 134 bits (334), Expect = 2e-30
Identities = 114/390 (29%), Positives = 175/390 (44%), Gaps = 38/390 (9%)
Query: 8 KKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAM 67
K ++G+ A A A V +YPITPQ+ + E G + Y ESE M
Sbjct: 33 KHFITGSEAVKEAAKRASVDASISYPITPQSEAAHMLGELWREGYIGV-YFRGESEFGVM 91
Query: 68 AACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQTD 127
+ G + GAR T TS G E+ AG+RLPI +V + R + P S+ D +
Sbjct: 92 SEVAGCAMAGARTITTTSGPGTMRAMEVFPMWAGSRLPIQLVLMARGINSPLSIQPDNLE 151
Query: 128 SLSQRDTGWMQFYAENNQEVYDGVLMAFKVAE--TVNVPAMVVESAFILSHTYEIVNMIP 185
DTG M ++AE QE++D ++ F VAE V+VP + F +SHT E V + P
Sbjct: 152 ISFLLDTGCMVWHAETAQELFDMIIAGFVVAEQPDVHVPIITAIDGFFISHTREAVYLPP 211
Query: 186 QELVDEFLPPRKPLYS---LADFENP---------IAVGALATPADYYEFRYKLARAHEE 233
+++ LPP P + D E P + + A + +++++ A E
Sbjct: 212 EDIA---LPPYNPYKAPMPPIDMEMPPGRFMRDPFVMKSNYISYATHASWQFEVRAAIER 268
Query: 234 AKKVIKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVE-LLRKQGYK 292
++ K R E FG E++ F+ G+ KEA + L+ ++G K
Sbjct: 269 SRPYAKHYLRGLVEHFGDPEGEVL-----------FIASGTAAAQAKEATQILIHEEGIK 317
Query: 293 VGYAKVRWFRPFPREELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIMK 352
+++ RPFP EE+ E + K I + + F G L E K ALY PI
Sbjct: 318 ARVLRLKTLRPFPTEEVREAVKGAKYIFIPE----FNVVGWLEREVKRALYGYTDIPIFG 373
Query: 353 NYIVGLG---GRDFTVSDV-KAIAEDMKKV 378
VG G +F V +V + I +++K V
Sbjct: 374 TPRVGGGMTMPPEFIVQEVLRLIGKEVKHV 403
>sp|P52965|NIFJ_SYNY3 PUTATIVE PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|7431613|pir||S77082
pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) nifJ -
Synechocystis sp. (strain PCC 6803)
>gi|1006618|dbj|BAA10774.1| (D64005) pyruvate
oxidoreductase [Synechocystis sp.]
Length = 1199
Score = 132 bits (328), Expect = 9e-30
Identities = 107/383 (27%), Positives = 180/383 (46%), Gaps = 13/383 (3%)
Query: 6 PIKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQ-----YIPV 60
P + GN A A V + +V+A YPITP + + E + A ++ + +
Sbjct: 4 PTYATLDGNEAVA-RVAYLLSEVIAIYPITPSSPMGEWSDAWAAEHRPNLWGTVPLVVEM 62
Query: 61 ESEHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPW- 119
+SE A GA +GA T T++QGL LM +H AG +V+ R++A
Sbjct: 63 QSEGGAAGTVHGALQSGALTTTFTASQGLMLMLPNMHKIAGELTAMVLHVAARSLAAQGL 122
Query: 120 SVWDDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYE 179
S++ D +D ++ R+TG+ + + QE +D L+A + +P + F SH +
Sbjct: 123 SIFGDHSDVMAARNTGFAMLSSNSVQEAHDFALIATATSFATRIPGLHFFDGFRTSHEEQ 182
Query: 180 IVNMIPQELVDEFLPPRKPLYSLADF---ENPIAVGALATPADYYEFRYKLARAHEEAKK 236
+ ++PQE++ + L + P G P Y++ R + +
Sbjct: 183 KIELLPQEVLRGLIKDEDVLAHRGRALTPDRPKLRGTAQNPDVYFQARETVNPFYASYPN 242
Query: 237 VIKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYA 296
V++ V +FG+ GR Y E +A+ V + MGS T +E V+ L QG KVG
Sbjct: 243 VLEQVMEQFGQLTGRHY-RPYEYCGHPEAERVIVLMGSGAETAQETVDFLTAQGEKVGLL 301
Query: 297 KVRWFRPFPREELLE-IAESVKGIAVLDRNFSFGQEG-ILFTEAKGALYNNGARPIMKNY 354
KVR +RPF + L+ + ++V+ IAVLDR G G L+ + A + G P +
Sbjct: 302 KVRLYRPFAGDRLVNALPKTVQKIAVLDRCKEPGSIGEPLYQDVLTAFFEAGMMPKIIGG 361
Query: 355 IVGLGGRDFTVSDVKAIAEDMKK 377
GL ++FT + VK + + + +
Sbjct: 362 RYGLSSKEFTPAMVKGVLDHLNQ 384
>sp|P52647|NIFJ_ECOLI PROBABLE PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|7431614|pir||E64888
probable pyruvate (flavodoxin) dehydrogenase (EC
1.2.99.-) ydbK - Escherichia coli
>gi|1742250|dbj|BAA14982.1| (D90775) Pyruvate-flavodoxin
oxidoreductase (EC 1.-.-.-). [Escherichia coli]
>gi|1742256|dbj|BAA14987.1| (D90776) Pyruvate-flavodoxin
oxidoreductase (EC 1.-.-.-). [Escherichia coli]
>gi|1787642|gb|AAC74460.1| (AE000234) putative
oxidoreductase, Fe-S subunit [Escherichia coli K12]
Length = 1174
Score = 131 bits (325), Expect = 2e-29
Identities = 117/386 (30%), Positives = 182/386 (46%), Gaps = 27/386 (6%)
Query: 11 VSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADI-----QYIPVESEHS 65
+ GN A A +V +V+A YPITP +++ E+ + NG ++ + + ++SE
Sbjct: 4 IDGNGAVA-SVAFRTSEVIAIYPITPSSTMAEQADAWAGNGLKNVWGDTPRVVEMQSEAG 62
Query: 66 AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAP-PWSVWDD 124
A+A GA TGA + TS+QGL LM L+ AG P V+ R +A S++ D
Sbjct: 63 AIATVHGALQTGALSTSFTSSQGLLLMIPTLYKLAGELTPFVLHVAARTVATHALSIFGD 122
Query: 125 QTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNMI 184
+D ++ R TG A N QE D L++ VP + F SH EI ++
Sbjct: 123 HSDVMAVRQTGCAMLCAANVQEAQDFALISQIATLKSRVPFIHFFDGFRTSH--EINKIV 180
Query: 185 PQELVDEFLPPRKPLYSL-------ADFENPIAVGALATPADYYEFRYKLARAHEEAKKV 237
P L D+ + P + + E+P+ G A P Y++ R +
Sbjct: 181 P--LADDTILDLMPQVEIDAHRARALNPEHPVIRGTSANPDTYFQSREATNPWYNAVYDH 238
Query: 238 IKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAK 297
++ +F GR Y + E A+ V + MGS +GT +E V+ L +G KVG K
Sbjct: 239 VEQAMNDFSAATGRQY-QPFEYYGHPQAERVIILMGSAIGTCEEVVDELLTRGEKVGVLK 297
Query: 298 VRWFRPFPREELLE-IAESVKGIAVLDRNFSFG-QEGILFTEAKGAL---YNNGARPIMK 352
VR +RPF + LL+ + SV+ +AVLDR G Q L+ + AL +NNG R +
Sbjct: 298 VRLYRPFSAKHLLQALPGSVRSVAVLDRTKEPGAQAEPLYLDVMTALAEAFNNGERETLP 357
Query: 353 NYI---VGLGGRDFTVSDVKAIAEDM 375
I GL ++F V A+ ++
Sbjct: 358 RVIGGRYGLSSKEFGPDCVLAVFAEL 383
>pir||G71262 probable pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) TP0939 -
syphilis spirochete >gi|3323259|gb|AAC65895.1|
(AE001262) pyruvate oxidoreductase [Treponema pallidum]
Length = 1184
Score = 129 bits (321), Expect = 6e-29
Identities = 107/386 (27%), Positives = 180/386 (45%), Gaps = 23/386 (5%)
Query: 10 VVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADI-----QYIPVESEH 64
++ GN A + V HA +V+A +PITP + + E E+ A G +I + ++SE
Sbjct: 8 MMDGNTAVGH-VAHALSEVIAIFPITPSSPMGEIADEYSARGRTNIWGTVPTVVELQSEA 66
Query: 65 SAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPP-WSVWD 123
A A GA TGA T T++QGL LM ++ AG V RA+A S++
Sbjct: 67 GASGAVHGALTTGALSSTFTASQGLLLMIPNMYKIAGELTSAVFHVAARAVATSSLSIFG 126
Query: 124 DQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNM 183
D D ++ R TGW + + QE D ++A VP + F SH + +
Sbjct: 127 DHQDVMACRQTGWALLASNSVQEAMDTAVIAHAATLEARVPFVHFFDGFRTSHEIQKIEE 186
Query: 184 IPQE----LVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIK 239
+ + ++D+ L + L E P+ G P Y++ R + R + A +++
Sbjct: 187 VSYDVMRAMIDDELVHAHRMRGLTP-EKPVVRGTAQNPDVYFQVRESVNRYYAVAPSIVQ 245
Query: 240 DVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVR 299
+ GR Y + + DA+ V + +GS V+E V++L QG K G KVR
Sbjct: 246 KAMDRYAALTGRQY-RLFDYYGAPDAEKVIVMIGSGSEAVEETVDVLNAQGGKCGLVKVR 304
Query: 300 WFRPFPREELLE-IAESVKGIAVLDRNFSFGQEG-ILFTEAKGALYNNGAR--------P 349
+RPF E + + ++V+ IAVLDR G G L+ + + A+ ++ P
Sbjct: 305 LYRPFSAECFVNALPKTVQAIAVLDRTKEPGSLGEPLYEDVRTAIGQMQSQKKCPFTHYP 364
Query: 350 IMKNYIVGLGGRDFTVSDVKAIAEDM 375
++ GLG ++FT + K + +++
Sbjct: 365 LVLGGRYGLGSKEFTPAMAKGVFDNL 390
>emb|CAA70873.1| (Y09702) pyruvate-ferredoxin oxidoreductase [Desulfovibrio
africanus]
Length = 1232
Score = 129 bits (320), Expect = 7e-29
Identities = 112/379 (29%), Positives = 181/379 (47%), Gaps = 22/379 (5%)
Query: 13 GNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADI--QYIPV---ESEHSAM 67
GN A A+ V +A +V A YPITP +++ E+ ++ A G +I Q + + +SE A
Sbjct: 10 GNTATAH-VAYAMSEVAAIYPITPSSTMGEEADDWAAQGRKNIFGQTLTIREMQSEAGAA 68
Query: 68 AACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAP-PWSVWDDQT 126
A GA A GA T T++QGL LM ++ +G LP V RA+A S++ D
Sbjct: 69 GAVHGALAAGALTTTFTASQGLLLMIPNMYKISGELLPGVFHVTARAIAAHALSIFGDHQ 128
Query: 127 DSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNMIPQ 186
D + R TG+ + + QE +D L+A A NVP M F SH + + ++
Sbjct: 129 DIYAARQTGFAMLASSSVQEAHDMALVAHLAAIESNVPFMHFFDGFRTSHEIQKIEVLDY 188
Query: 187 ELVDEFLPPRKPLYSLADF-------ENPIAVGALATPADYYEFRYKLARAHEEAKKVIK 239
+ + + +LA+F E+P G P Y++ R + + ++
Sbjct: 189 ADMASLVNQK----ALAEFRAKSMNPEHPHVRGTAQNPDIYFQGREAANPYYLKVPGIVA 244
Query: 240 DVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVR 299
+ ++ GR Y ++ + DA+ V + MGS T++E + L +G K+G KVR
Sbjct: 245 EYMQKVASLTGRSY-KLFDYVGAPDAERVIVSMGSSCETIEEVINHLAAKGEKIGLIKVR 303
Query: 300 WFRPFPREELL-EIAESVKGIAVLDRNFSFGQEG-ILFTEAKGALYNNG-ARPIMKNYIV 356
+RPF E + S K I VLDR G G L+ + A G A P +
Sbjct: 304 LYRPFVSEAFFAALPASAKVITVLDRTKEPGAPGDPLYLDVCSAFVERGEAMPKILAGRY 363
Query: 357 GLGGRDFTVSDVKAIAEDM 375
GLG ++F+ + VK++ ++M
Sbjct: 364 GLGSKEFSPAMVKSVYDNM 382
>pdb|1B0P|A Chain A, Crystal Structure Of Pyruvate-Ferredoxin Oxidoreductase
From Desulfovibrio Africanus >gi|4558092|pdb|1B0P|B
Chain B, Crystal Structure Of Pyruvate-Ferredoxin
Oxidoreductase From Desulfovibrio Africanus
>gi|4558221|pdb|2PDA|A Chain A, Crystal Structure Of The
Complex Between Pyruvate- Ferredoxin Oxidoreductase From
Desulfovibrio Africanus And Pyruvate.
>gi|4558222|pdb|2PDA|B Chain B, Crystal Structure Of The
Complex Between Pyruvate- Ferredoxin Oxidoreductase From
Desulfovibrio Africanus And Pyruvate
Length = 1231
Score = 129 bits (320), Expect = 7e-29
Identities = 112/379 (29%), Positives = 181/379 (47%), Gaps = 22/379 (5%)
Query: 13 GNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADI--QYIPV---ESEHSAM 67
GN A A+ V +A +V A YPITP +++ E+ ++ A G +I Q + + +SE A
Sbjct: 9 GNTATAH-VAYAMSEVAAIYPITPSSTMGEEADDWAAQGRKNIFGQTLTIREMQSEAGAA 67
Query: 68 AACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAP-PWSVWDDQT 126
A GA A GA T T++QGL LM ++ +G LP V RA+A S++ D
Sbjct: 68 GAVHGALAAGALTTTFTASQGLLLMIPNMYKISGELLPGVFHVTARAIAAHALSIFGDHQ 127
Query: 127 DSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNMIPQ 186
D + R TG+ + + QE +D L+A A NVP M F SH + + ++
Sbjct: 128 DIYAARQTGFAMLASSSVQEAHDMALVAHLAAIESNVPFMHFFDGFRTSHEIQKIEVLDY 187
Query: 187 ELVDEFLPPRKPLYSLADF-------ENPIAVGALATPADYYEFRYKLARAHEEAKKVIK 239
+ + + +LA+F E+P G P Y++ R + + ++
Sbjct: 188 ADMASLVNQK----ALAEFRAKSMNPEHPHVRGTAQNPDIYFQGREAANPYYLKVPGIVA 243
Query: 240 DVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVR 299
+ ++ GR Y ++ + DA+ V + MGS T++E + L +G K+G KVR
Sbjct: 244 EYMQKVASLTGRSY-KLFDYVGAPDAERVIVSMGSSCETIEEVINHLAAKGEKIGLIKVR 302
Query: 300 WFRPFPREELL-EIAESVKGIAVLDRNFSFGQEG-ILFTEAKGALYNNG-ARPIMKNYIV 356
+RPF E + S K I VLDR G G L+ + A G A P +
Sbjct: 303 LYRPFVSEAFFAALPASAKVITVLDRTKEPGAPGDPLYLDVCSAFVERGEAMPKILAGRY 362
Query: 357 GLGGRDFTVSDVKAIAEDM 375
GLG ++F+ + VK++ ++M
Sbjct: 363 GLGSKEFSPAMVKSVYDNM 381
>pir||A81294 pyruvate-flavodoxin oxidoreductase Cj1476c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968902|emb|CAB73898.1| (AL139078)
pyruvate-flavodoxin oxidoreductase [Campylobacter
jejuni]
Length = 1186
Score = 128 bits (319), Expect = 1e-28
Identities = 108/381 (28%), Positives = 175/381 (45%), Gaps = 13/381 (3%)
Query: 7 IKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPV-----E 61
I K + GN AAAYA +A +V YPITP + + + + A G+ ++ +PV +
Sbjct: 4 IMKTMDGNEAAAYAA-YAFTEVAGIYPITPSSPMADYTDMWAAAGKKNLFGVPVKIVEMQ 62
Query: 62 SEHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPP-WS 120
SE A + G+ GA T T++QGL L ++ AG LP V+ R++A S
Sbjct: 63 SEAGAAGSVHGSLQAGALTTTYTASQGLLLKIPNMYKIAGQLLPCVIHVAARSLAAQALS 122
Query: 121 VWDDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEI 180
++ D D + R G+ + + QE D +A A VP + F SH +
Sbjct: 123 IFGDHQDIYAARQIGFAMLCSHSVQETMDLAGVAHLAAIKGRVPFLHFFDGFRTSHEIQK 182
Query: 181 VNMIPQELVDEFLPPRKPLY---SLADFENPIAVGALATPADYYEFRYKLARAHEEAKKV 237
V ++ D L L + + ENP G Y++ R R ++ V
Sbjct: 183 VEVMDYAHFDRLLDREALLEFRNNALNPENPKTRGTAQNDDIYFQTREVSNRFYDALPDV 242
Query: 238 IKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAK 297
+ + +E + GR+Y + + + V + MGS+ ++E V+ L +G KVG K
Sbjct: 243 VNEYMQEISKITGREYKPFTYYGH-KEPECVIVAMGSVTQALEEVVDYLNAKGEKVGILK 301
Query: 298 VRWFRPFPREELLEI-AESVKGIAVLDRNFSFGQEG-ILFTEAKGALYNNGARPIMKNYI 355
V +RPF + ++ +SVK IAVLDR G G L+ + K A Y P++
Sbjct: 302 VYLYRPFSLKYFFDVMPKSVKKIAVLDRTKEPGSLGEPLYLDVKSAFYGRENAPVIVGGR 361
Query: 356 VGLGGRDFTVSDVKAIAEDMK 376
GL +D + + A+ E++K
Sbjct: 362 YGLSSKDVDPAQMIAVFENLK 382
>sp|Q06879|NIFJ_ANASP PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|2126544|pir||I39613 pyruvate
(flavodoxin) dehydrogenase nifJ (EC 1.2.99.-) - Anabaena
sp >gi|289139|gb|AAC36818.1| (L14925) nitrogen fixation
protein [Anabaena sp.]
Length = 1197
Score = 122 bits (303), Expect = 7e-27
Identities = 110/390 (28%), Positives = 185/390 (47%), Gaps = 27/390 (6%)
Query: 11 VSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADI-----QYIPVESEHS 65
+ GN A A V + +V+A YPITP +++ E ++A G ++ + ++SE
Sbjct: 8 IDGNEAVA-RVAYKLNEVIAIYPITPSSAMGEWADAWMAEGRPNLWGTVPSVVQMQSEGG 66
Query: 66 AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAP-PWSVWDD 124
A A GA TG+ T T++QGL LM L+ G +V+ R++A S++ D
Sbjct: 67 AAGAVHGALQTGSLSTTFTASQGLLLMIPNLYKIGGELTSMVVHVAARSLATHALSIFGD 126
Query: 125 QTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNMI 184
+D ++ R TG+ + + QE +D L+A V + F SH + V ++
Sbjct: 127 HSDVMAARGTGFAMLCSASVQESHDFALIAHAATLDTRVSFLHFFDGFRTSHEVQKVELL 186
Query: 185 PQELVDEFLPPRKPLYSLADF---ENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDV 241
+ V + K A ++P+ G P +++ R + +++ +
Sbjct: 187 ADDDVRSLINEDKIFAHRARALTPDSPLLRGTAQNPDVFFQAREGANPYYNACPAIVQGI 246
Query: 242 -GREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRW 300
+ FGER GR Y ++ E DAD + + MGS TV E V+ L +G KVG KVR
Sbjct: 247 MDKFFGERTGR-YYQIYEYHGASDADRLIIIMGSGCETVHETVDYLNARGEKVGVLKVRL 305
Query: 301 FRPFPREELLE-IAESVKGIAVLDRNFSFGQEG-ILFTEAKGALY------NNGARPIMK 352
FRP+ E ++ + SV+ IAVLDR G G L+ + A++ NN P +
Sbjct: 306 FRPWDVERFVQALPHSVQAIAVLDRTKEPGSAGEPLYQDVVTAIHEGWVNKNNSPVPSPQ 365
Query: 353 NYI-------VGLGGRDFTVSDVKAIAEDM 375
+ + GL ++FT + VKA+ +++
Sbjct: 366 SPVPKIIGGRYGLSSKEFTPAMVKAVFDNL 395
>emb|CAB43934.1| (Y17727) pyruvate ferredoxin oxidoreductase [Clostridium
pasteurianum]
Length = 1181
Score = 120 bits (297), Expect = 4e-26
Identities = 106/382 (27%), Positives = 174/382 (44%), Gaps = 14/382 (3%)
Query: 8 KKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADI-----QYIPVES 62
K+ + GN AAA+ V +A V YPITP + + + + + A G+ +I + + ++S
Sbjct: 5 KQSMDGNTAAAH-VAYAYTDVAGIYPITPSSPMADSVDMWSAAGQENIFGNQVKVVEMQS 63
Query: 63 EHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVM-VDVNRAMAPPWSV 121
E A G+ A GA T T++QGL LM ++ AG LP V V + ++
Sbjct: 64 EAGAAGTVHGSLAAGALTTTFTASQGLLLMIPNMYKIAGEMLPSVFHVSARTVASHALNI 123
Query: 122 WDDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIV 181
+ D +D + R G+ N QEV D +A A VP + F SH + +
Sbjct: 124 FGDHSDVYACRQVGFAMLAETNPQEVMDLSPVAHLAALEGKVPFINFFDGFRTSHEIQKI 183
Query: 182 NMIPQELVDEF--LPPRKPLYSLA-DFENPIAVGALATPADYYEFRYKLARAHEEAKKVI 238
E + E + K A + E P G+ +++ R A+ ++
Sbjct: 184 EKWDYEDLKEMCNMDAVKAFRDHALNPEKPAMRGSHENGDVFFQHREACNTAYNNLPAIV 243
Query: 239 KDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKV 298
+ + E+ G DY ++ +DAD V + MGS+ +E ++ L +G KVG KV
Sbjct: 244 EKYMAKVNEKLGTDY-DLFNYYGAEDADRVIIAMGSICDVAEEVIDYLTAKGEKVGLVKV 302
Query: 299 RWFRPFPREELLE-IAESVKGIAVLDRNFSFGQEG-ILFTEAKGALYNNGARPIMKNY-I 355
R +RP+ E +L+ + ++ K +AVLDR G G L+ + L G I+
Sbjct: 303 RLYRPWVSESILKALPKTAKKVAVLDRTKEPGALGDPLYLDVATTLREAGLNDIILTAGR 362
Query: 356 VGLGGRDFTVSDVKAIAEDMKK 377
GLG +D S V A+ ++ K
Sbjct: 363 YGLGSKDTPPSSVFAVYTELSK 384
>sp|Q53046|NIFJ_RHORU PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|628896|pir||S41961 pyruvate
oxidoreductase - Rhodospirillum rubrum
>gi|453436|emb|CAA54651.1| (X77515) pyruvate
oxidoreductase [Rhodospirillum rubrum]
Length = 1191
Score = 118 bits (294), Expect = 8e-26
Identities = 107/387 (27%), Positives = 178/387 (45%), Gaps = 23/387 (5%)
Query: 11 VSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADI-----QYIPVESEHS 65
+ GN A A +V + +V YPITP +++ E E+ A G +I Q + ++SE
Sbjct: 9 IDGNEACA-SVAYRVSEVAVIYPITPSSTMGELSDEWSAKGLTNIWGAVPQVVEMQSEGG 67
Query: 66 AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAP-PWSVWDD 124
A AC GA TG+ T T++QGL LM ++ AG P M R +A S++ D
Sbjct: 68 AAGACHGAIQTGSLGTTFTASQGLLLMIPNMYKIAGELTPFCMHVTARTLATHALSIFGD 127
Query: 125 QTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNMI 184
Q+D ++ R TG+ + + QE +D +A + +P + F SH + ++
Sbjct: 128 QSDVMACRQTGFAILASASVQEAHDLASVAHGASLESRIPFLHFFDGFRTSHEVNKIELM 187
Query: 185 PQE----LVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKD 240
+ ++D+ L +L + P+ G P +++ + ++ +++
Sbjct: 188 TDDDLHAMIDDDLVAAHRARALTP-DTPVTRGTAQNPDTFFQAQEARNPFYDACPAIVQS 246
Query: 241 VGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRW 300
GR Y + + A+ V + MGS TV E V+ L +G K+G KVR
Sbjct: 247 YMDRLAALTGRRYG-LFDYVGHPQAERVVVIMGSGAETVAETVDWLVARGEKIGVVKVRL 305
Query: 301 FRPFPREELL-EIAESVKGIAVLDRNFSFGQEG-ILFTEAKGALYNNGARPIMKNYI--- 355
FRPF + + + SV+ IAVLDR G G L+ + GAL A + +
Sbjct: 306 FRPFSVDAFVAALPVSVRAIAVLDRCKESGAIGEPLYLDVVGALARAKALGLRAGIVDPA 365
Query: 356 -----VGLGGRDFTVSDVKAIAEDMKK 377
GL ++FT + VKAI +++ K
Sbjct: 366 VIGGRYGLSSKEFTPAMVKAIFDELAK 392
>gb|AAB49653.1| (U30149) pyruvate:ferredoxin oxidoreductase [Entamoeba histolytica]
Length = 1162
Score = 118 bits (294), Expect = 8e-26
Identities = 106/377 (28%), Positives = 176/377 (46%), Gaps = 13/377 (3%)
Query: 11 VSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADI--QYIPV---ESEHS 65
V GN AAAY V +A V +PITP + + E + + G ++ Q + V ESE
Sbjct: 4 VDGNQAAAY-VSYALSDVSFIFPITPSSPMAENADVWSSQGRKNVFGQVVDVYEMESEAG 62
Query: 66 AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMA-PPWSVWDD 124
A A G A G+ V T T +QGL LM + AG LP V RA+A S++ D
Sbjct: 63 ASGAVHGGCAAGSLVSTYTCSQGLMLMIPNMIKIAGEHLPCVFHVTARALAGQALSIFGD 122
Query: 125 QTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNMI 184
+D ++ R TG+ + N Q+ +D ++A ++P M F SH + ++ +
Sbjct: 123 HSDVMACRSTGFCLLSSHNVQQCHDLAIVAHLATLEASLPFMHFFDGFRTSHEIQKIHQL 182
Query: 185 PQELVDEFLPPRKPLYSLADFENPIAVGALAT---PADYYEFRYKLARAHEEAKKVIKDV 241
+ + + + + NPI T P +++ K + + ++++
Sbjct: 183 TYDQIKSLVDMKYVDRAHKRGLNPIHPSQRGTSQGPDVFFQAVEKSNADYLKVPEIVQKY 242
Query: 242 GREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWF 301
+ GE GR Y ++ E DA+ V + MG+ + ++E V+ L K G KVG V +
Sbjct: 243 MDKVGELTGRHY-KIFEYYGAADAERVVVVMGAAVPVLEECVDYLMKSGEKVGVLSVHLY 301
Query: 302 RPFPREELLE-IAESVKGIAVLDRNFSFGQEG-ILFTEAKGALYNNGARPIMKNYIVGLG 359
RP+ + LE + +V I+VLDR G G L+ + L + G GLG
Sbjct: 302 RPWSAKHFLEQLPNTVTKISVLDRTKEAGSFGEPLYLDVATTLLDAGKHIKCVGGRYGLG 361
Query: 360 GRDFTVSDVKAIAEDMK 376
++FT + KA+ +++K
Sbjct: 362 SKEFTPAMAKAVFDNLK 378
>pir||S70963 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) - Rhodospirillum
rubrum
Length = 1191
Score = 118 bits (294), Expect = 8e-26
Identities = 107/387 (27%), Positives = 178/387 (45%), Gaps = 23/387 (5%)
Query: 11 VSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADI-----QYIPVESEHS 65
+ GN A A +V + +V YPITP +++ E E+ A G +I Q + ++SE
Sbjct: 9 IDGNEACA-SVAYRVSEVAVIYPITPSSTMGELSDEWSAKGLTNIWGAVPQVVEMQSEGG 67
Query: 66 AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAP-PWSVWDD 124
A AC GA TG+ T T++QGL LM ++ AG P M R +A S++ D
Sbjct: 68 AAGACHGAIQTGSLGTTFTASQGLLLMIPNMYKIAGELTPFCMHVTARTLATHALSIFGD 127
Query: 125 QTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNMI 184
Q+D ++ R TG+ + + QE +D +A + +P + F SH + ++
Sbjct: 128 QSDVMACRQTGFAILASASVQEAHDLASVAHGASLESRIPFLHFFDGFRTSHEVNKIELM 187
Query: 185 PQE----LVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKD 240
+ ++D+ L +L + P+ G P +++ + ++ +++
Sbjct: 188 TDDDLHAMIDDDLVAAHRARALTP-DTPVTRGTAQNPDTFFQAQEARNPFYDACPAIVQS 246
Query: 241 VGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRW 300
GR Y + + A+ V + MGS TV E V+ L +G K+G KVR
Sbjct: 247 YMDRLAALTGRRYG-LFDYVGHPQAERVVVIMGSGAETVAETVDWLVARGEKIGVVKVRL 305
Query: 301 FRPFPREELL-EIAESVKGIAVLDRNFSFGQEG-ILFTEAKGALYNNGARPIMKNYI--- 355
FRPF + + + SV+ IAVLDR G G L+ + GAL A + +
Sbjct: 306 FRPFSVDAFVAALPVSVRAIAVLDRCKESGAIGEPLYLDVVGALARAKALGLRAGIVDPA 365
Query: 356 -----VGLGGRDFTVSDVKAIAEDMKK 377
GL ++FT + VKAI +++ K
Sbjct: 366 VIGGRYGLSSKEFTPAMVKAIFDELAK 392
>pir||C75168 2-ketoglutarate ferredoxin oxidoreductase, chain alpha (kora-1)
PAB2359 - Pyrococcus abyssi (strain Orsay)
>gi|5457936|emb|CAB49426.1| (AJ248284) 2-ketoglutarate
ferredoxin oxidoreductase, subunit alpha (korA-1)
[Pyrococcus abyssi]
Length = 408
Score = 113 bits (280), Expect = 4e-24
Identities = 98/349 (28%), Positives = 155/349 (44%), Gaps = 39/349 (11%)
Query: 4 YKPIKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESE 63
YKP + G+ A AY + A + A YPITP + I E +A + + Y+ +E E
Sbjct: 30 YKPGNYFMMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDE 87
Query: 64 HSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRA-MAPPWSVW 122
+++AA +GAS TG +V TATS G +LM E L +A P+V+VDV R+ + +
Sbjct: 88 IASIAAMVGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATK 147
Query: 123 DDQTDSLSQR-----DTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHT 177
Q D R D + + ++ + + AF VAE + P +V+ IL HT
Sbjct: 148 GAQGDFFQARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAERLRTPVVVLFDG-ILGHT 206
Query: 178 YE------------IVNMIPQELVDEFLP---------PRKPLYSLADFENPIAVGALAT 216
E + +PQ + LP P PL+ F + T
Sbjct: 207 REQIRIPDPDEVEIVYRKLPQNEEEARLPFGDPHGDGVPPMPLFGHGYFTH-------VT 259
Query: 217 PADYYEFRYKLARAHEEAKKVIKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLM 276
+ + E + E K+++ + R+ + R+ E E+ Y DDA+ + + G
Sbjct: 260 GSTHKENGLRDVYTQEVHDKLVRRIHRKIEQ--NREVYEKYEEYYTDDAEILVVSWGVSA 317
Query: 277 GTVKEAVELLRKQGYKVGYAKVRWFRPFPREELLEIAESVKGIAVLDRN 325
AV RK+G KVG + PFP E + E+ + V+ I V + N
Sbjct: 318 RPSLGAVLKARKEGIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMN 366
>emb|CAA57480.1| (X81893) nifJ [Enterobacter agglomerans]
Length = 308
Score = 109 bits (271), Expect = 4e-23
Identities = 88/306 (28%), Positives = 143/306 (45%), Gaps = 13/306 (4%)
Query: 9 KVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEAD-----IQYIPVESE 63
K + GN AAAY V +A V A YPITP T + E + E+ A G+ + ++ + ++SE
Sbjct: 6 KTMDGNTAAAY-VSYAFTDVTAIYPITPSTPMAESVDEWAAQGKKNLFGQTVKVMEMQSE 64
Query: 64 HSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAP-PWSVW 122
A A GA GA T T++QGL LM ++ AG LP V RA+A +++
Sbjct: 65 SGAAGAIHGALQAGALATTYTASQGLLLMTPNMYKIAGELLPAVFHVSARALATNSLNIF 124
Query: 123 DDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVN 182
D D ++ R TG + Q+V D +A A +P + F SH + +
Sbjct: 125 GDHQDVMAVRQTGCAMLAESSVQQVMDLAAVAHLTAIKGRIPFINFFDGFRTSHEIQKIE 184
Query: 183 MIPQE----LVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVI 238
++ E L+D R +L ++P+ G P Y++ R + + +++
Sbjct: 185 VLDYEELAALLDWDAVTRFRQNALHP-DHPVVRGTAQNPDIYFQEREASNKFYMALPEMV 243
Query: 239 KDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKV 298
+ + + GR+Y + DA + + MGS+ T++E V+ L G KVG V
Sbjct: 244 ESYMAKISKLTGREY-HLFNYYGAPDAGRMIIAMGSVCETIQETVDYLNASGEKVGVLTV 302
Query: 299 RWFRPF 304
+RPF
Sbjct: 303 HLYRPF 308
>dbj|BAB12024.1| (AB021127) pyruvate:NADP+ oxidoreductase [Euglena gracilis]
Length = 1803
Score = 107 bits (265), Expect = 2e-22
Identities = 103/374 (27%), Positives = 168/374 (44%), Gaps = 15/374 (4%)
Query: 11 VSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEAD-----IQYIPVESEHS 65
V G+ A ++ V +A YPITP + + E ++A G + + ++SE
Sbjct: 72 VDGSQATSH-VAYALSDTAFIYPITPSSVMGELADVWMAQGRKNAFGQVVDVREMQSEAG 130
Query: 66 AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAP-PWSVWDD 124
A A GA A GA T T++QGL LM ++ AG +P V+ R +A S++
Sbjct: 131 AAGALHGALAAGAIATTFTASQGLLLMIPNMYKIAGELMPSVIHVAARELAGHALSIFGG 190
Query: 125 QTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNMI 184
D ++ R TGW + Q+ +D L++ ++P + F SH + M+
Sbjct: 191 HADVMAVRQTGWAMLCSHTVQQSHDMALISHVATLKSSIPFVHFFDGFRTSHEVNKIKML 250
Query: 185 PQELVDEFLPPRKPLYSLADFENPI--AVGALATPAD-YYEFRYKLARAHEEAKKVIKDV 241
P + + +PP A NP+ + AD Y++ + + + +V+++
Sbjct: 251 PYAELKKLVPPGTMEQHWARSLNPMHPTIRGTNQSADIYFQNMESANQYYTDLAEVVQET 310
Query: 242 GREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWF 301
E GR Y ++ E DA+ V + MGS TV EAV+LL K+G KVG V +
Sbjct: 311 MDEVAPYIGRHY-KIFEYVGAPDAEEVTVLMGSGATTVNEAVDLLVKRGKKVGAVLVHLY 369
Query: 302 RPFPREELLEI-AESVKGIAVLDR---NFSFGQEGILFTEAKGALYNNGARPIMKNYIVG 357
RP+ + ++ ++VK IA LDR + G+ L A L+ + G
Sbjct: 370 RPWSTKAFEKVLPKTVKRIAALDRCKEVTALGEPLYLDVSATLNLFPERQNVKVIGGRYG 429
Query: 358 LGGRDFTVSDVKAI 371
LG +DF AI
Sbjct: 430 LGSKDFIPEHALAI 443
>pir||S58236 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) - Entamoeba
histolytica >gi|929587|emb|CAA90575.1| (Z50193) pyruvate
oxidoreductase [Entamoeba histolytica]
Length = 1165
Score = 106 bits (262), Expect = 5e-22
Identities = 105/380 (27%), Positives = 172/380 (44%), Gaps = 16/380 (4%)
Query: 11 VSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADI--QYIPV---ESEHS 65
V GN AAAY V +A V +PITP + + E + + G ++ Q + V ESE
Sbjct: 4 VDGNQAAAY-VSYALSDVSFIFPITPSSPMAENADVWSSQGRKNVFGQVVDVYEMESEAG 62
Query: 66 AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMA-PPWSVWDD 124
A A G A G+ V T T +QGL LM + AG LP V RA+A S++ D
Sbjct: 63 ASGAVHGGCAAGSLVSTYTCSQGLMLMIPNMIKIAGEHLPCVFHVTARALAEQALSIFGD 122
Query: 125 QTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNMI 184
+D ++ R TG+ + N Q+ +D ++A ++P M F SH + ++ +
Sbjct: 123 HSDVMACRSTGFCLLSSHNVQQCHDLAIVAHLATLEASLPFMHFFDGFRTSHEIQKIHQL 182
Query: 185 PQELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEA-----KKVIK 239
+ + + + + NPI T L + A ++++
Sbjct: 183 TYDQIKSLVDMKYVDRAHKRGLNPIHPSQRGTSQGPDVILPSLLKIKSNADYLKVPEIVQ 242
Query: 240 DVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQ-GYKVGYAKV 298
+ GE GR Y ++ E DA+ V + MG+ + ++E V+ L K+ KVG V
Sbjct: 243 KYMDKVGELTGRHY-KIFEYYGAADAERVVVVMGAAVPVLEECVDYLMKELEEKVGVLSV 301
Query: 299 RWFRPFPREELLE-IAESVKGIAVLDRNFSFGQEG-ILFTEAKGALYNNGARPIMKNYIV 356
+RP+ + LE + +V I+VLDR G G L+ + L + G
Sbjct: 302 HLYRPWSAKHFLEQLPNTVTKISVLDRTKEAGLFGEPLYLDVATTLLDAGKHIKCVGGRY 361
Query: 357 GLGGRDFTVSDVKAIAEDMK 376
GLG ++FT + KA+ +++K
Sbjct: 362 GLGSKEFTPAMAKAVFDNLK 381
>pir||H72214 hypothetical protein TM1759 - Thermotoga maritima (strain MSB8)
>gi|4982338|gb|AAD36824.1|AE001814_6 (AE001814)
2-oxoisovalerate oxidoreductase, beta subunit, putative
[Thermotoga maritima]
Length = 356
Score = 104 bits (256), Expect = 2e-21
Identities = 92/329 (27%), Positives = 145/329 (43%), Gaps = 38/329 (11%)
Query: 8 KKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAM 67
K ++ GN A A + + A ++ AYPITPQ+ I E +A + E ++ ESE + +
Sbjct: 6 KLMMKGNEAIAESAIRAGCRLYFAYPITPQSEIAEYMARRLP--EVGGVFLQTESEIATV 63
Query: 68 AACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQTD 127
GA+ TG RV T+TS+ G +LM E + + AGA LP V VDV R ++ Q D
Sbjct: 64 NMVYGAACTGKRVMTSTSSPGFSLMQEGISYIAGAELPCVFVDVVRGGPGLGNIQPSQGD 123
Query: 128 SLSQRDTGWMQFY------AENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIV 181
G Y QE D +AF +A+ P +++
Sbjct: 124 YFQAVKGGGHGDYRLIVLAPSTLQEAVDLTQLAFDLADRYRNPVLILAD----------- 172
Query: 182 NMIPQELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDV 241
MI Q + LP + L +L D + GA + H A I V
Sbjct: 173 GMIGQMMEPVELPEMRDLSTLPDHSDWALRGA------------RNREPHRIAAFNIDPV 220
Query: 242 GRE-FGERFGRDY------SEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVG 294
G E +R Y + E+ +D A+++ +G G++ +K V+ LR++G G
Sbjct: 221 GLEKMNKRLQEKYRLIEASEQRWEEYRVDGAEYLMVGYGTMGRILKSVVDSLREEGIPAG 280
Query: 295 YAKVRWFRPFPREELLEIAESVKGIAVLD 323
+ PFP+ L E+A+ V+ I V++
Sbjct: 281 LFRPVTLWPFPKRRLKELAKKVQLIFVVE 309
>pir||B71047 probable ferredoxin oxidoreductase alpha subunit - Pyrococcus
horikoshii >gi|3258095|dbj|BAA30778.1| (AP000006) 408aa
long hypothetical ferredoxin oxidoreductase alpha
subunit [Pyrococcus horikoshii]
Length = 408
Score = 103 bits (255), Expect = 3e-21
Identities = 96/344 (27%), Positives = 153/344 (43%), Gaps = 29/344 (8%)
Query: 4 YKPIKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESE 63
Y+P + G+ A AY + A + A YPITP + I E +A + + Y+ +E E
Sbjct: 30 YRPGNYFMMGDEAIAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDE 87
Query: 64 HSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRA-MAPPWSVW 122
++AA IGAS TG + TATS G +LM E + +A PIV+V+V R+ + +
Sbjct: 88 IGSIAAMIGASWTGLKAMTATSGPGFSLMQENIGYAVMTETPIVVVNVQRSGPSTGQATK 147
Query: 123 DDQTDSLSQR-----DTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHT 177
Q D R D + + ++ + + AF +AE + P +V+ IL HT
Sbjct: 148 GAQGDFFQARWGTHGDHPMIAVSPISVEDAFWETIRAFNIAEKLRTPVIVLFDG-ILGHT 206
Query: 178 YEIVNMIPQ----ELVDEFLPPRKPLYSLADFENPIAVGALATPA-DYYEFRYKLARAHE 232
E + IP E+ LP + L F +P G P + F + H+
Sbjct: 207 REQIR-IPDPDEVEITYRKLPGSEEEAKL-PFGDPHGDGVPPMPLFGHGYFTHVTGSTHK 264
Query: 233 E-----------AKKVIKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKE 281
E K+++ + R+ + RD E E+ Y DDA+ + + G
Sbjct: 265 ENGLRDVYTQEVHDKLVRRIHRKIEQ--NRDVYEKYEEYYTDDAEILVVSWGVSARPSLG 322
Query: 282 AVELLRKQGYKVGYAKVRWFRPFPREELLEIAESVKGIAVLDRN 325
AV R++G K G + PFP E + E+ + V+ I V + N
Sbjct: 323 AVLKAREEGIKAGLFVPKTVHPFPGERMRELGKKVRAILVPEMN 366
>pir||T43259 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) pfoB precursor,
hydrogenosomal - Trichomonas vaginalis
>gi|622960|gb|AAA85495.1| (U16823) pyruvate:ferredoxin
oxidoreductase proprotein [Trichomonas vaginalis]
Length = 1157
Score = 102 bits (253), Expect = 5e-21
Identities = 108/386 (27%), Positives = 168/386 (42%), Gaps = 29/386 (7%)
Query: 8 KKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADI-----QYIPVES 62
K+V AA +V + + YPITP T++ E + +IA G +I ++S
Sbjct: 7 KRVPGDGNTAATSVAYQLTETSFIYPITPATTMGELVDAWIAQGRKNIWGNKVNMAMMQS 66
Query: 63 EHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMA-PPWSV 121
E A AA GA+A GA T T++QG LM ++ G P V R +A S+
Sbjct: 67 EGGAAAAVHGATAVGALCATFTASQGALLMIPDMYKIVGEMCPAVFHIAARCIATSALSI 126
Query: 122 WDDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSH---TY 178
++D D + R TG ++ QE +D +A + +P + F SH TY
Sbjct: 127 YNDHGDIYACRATGMPILFSNGVQEAHDLAAVAHLTSIHTGLPFIHTFDGFRTSHEINTY 186
Query: 179 EIVNMIPQELVDEFLPPRKPLYSLADF-------ENPIAVGALATPADYYEFRYKLARAH 231
E EL +E L P +LA F E+P G + P ++ KL + +
Sbjct: 187 E-------ELDNETLWPLIDQKALAAFRARSLNPEHPSERGTICGPEYVWQMHEKLRKPY 239
Query: 232 EEAKKVIKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGY 291
+ ++ + + G++ GR Y + + A D + V + MGS V+E + Y
Sbjct: 240 QALPAEVEKMMKALGDKTGR-YYKPYQYAGPRDPENVIIMMGSGCDPVEEFI--TEHPEY 296
Query: 292 KVGYAKVRWFRPFPREEL-LEIAESVKGIAVLDRNFS-FGQEGILFTEAKGALYNNGARP 349
K G KV +RPF E I SVK + VLD+ G LF + A+
Sbjct: 297 KTGLIKVYLYRPFSVEMFNAAIPSSVKRVCVLDKVVDPTGPREPLFEDVAAAIIGQRNVK 356
Query: 350 IMKNYIVGLGGRDFTVSDVKAIAEDM 375
I+ G+ RDF V+AI +++
Sbjct: 357 IIGGR-YGISSRDFAPVHVEAIVKNL 381
>pir||F71046 probable ferredoxin oxidoreductase alpha subunit - Pyrococcus
horikoshii >gi|3258091|dbj|BAA30774.1| (AP000006) 385aa
long hypothetical ferredoxin oxidoreductase alpha
subunit [Pyrococcus horikoshii]
Length = 385
Score = 102 bits (253), Expect = 5e-21
Identities = 98/335 (29%), Positives = 149/335 (44%), Gaps = 25/335 (7%)
Query: 11 VSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMAAC 70
+ G+ A A A + A + A YPITP + I E +A ++ + + I +E E ++AA
Sbjct: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLIDGVV--IQMEDEIGSIAAV 70
Query: 71 IGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNR----AMAPPWSVWDDQT 126
IGAS G + TATS G +LM E + +A PIV+V+V R P D
Sbjct: 71 IGASWAGVKAMTATSGPGFSLMQENIGYAVMTETPIVVVNVQRGGPSTGQPTLPSQGDIM 130
Query: 127 DSL--SQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNMI 184
S+ + D + QE +D + AF +AE P +++ A + H E V I
Sbjct: 131 QSIWGTHGDHTLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEV-GHMRERV-YI 188
Query: 185 PQ----ELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKD 240
P+ E+V+ LP + L F +P G P +R + + K +
Sbjct: 189 PEPDEIEIVNRKLPGSEEEAKL-PFGDPHGDGVPPMPIFGKGYRTYVTGLTHDEKGRPRT 247
Query: 241 VGREFGERFGRDYSEMIEK----------AYIDDADFVFMGMGSLMGTVKEAVELLRKQG 290
V RE ER R E IEK +DDA+ + G + + A++ LR G
Sbjct: 248 VEREVHERLIRRIFEKIEKNKKDIFDYEARELDDAEIAIVTTGIVARSALRAIKELRNLG 307
Query: 291 YKVGYAKVRWFRPFPREELLEIAESVKGIAVLDRN 325
K G K+ PF E + ++AE V+ I V + N
Sbjct: 308 IKAGLLKINTIWPFDFELIEKVAEKVERIYVPEMN 342
>sp|Q57724|KORA_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KETOGLUTARATE
OXIDOREDUCTASE ALPHA CHAIN) (KOR)
(2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT)
>gi|2127893|pir||E64334 2-oxoacid--ferredoxin
oxidoreductase (EC 1.2.7.-) alpha chain - Methanococcus
jannaschii >gi|1592279|gb|AAB98264.1| (U67483)
2-ketoglutarate ferredoxin oxidoreductase, subunit alpha
(korA) [Methanococcus jannaschii]
Length = 366
Score = 102 bits (251), Expect = 9e-21
Identities = 93/330 (28%), Positives = 144/330 (43%), Gaps = 24/330 (7%)
Query: 11 VSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMAAC 70
+ GN A A + A + A YPITP T I E +A + + YI +E E ++AA
Sbjct: 6 MQGNQACAKGAIKAGCRFFAGYPITPSTEIAEAMARELP--KVGGYYIQMEDEIGSIAAV 63
Query: 71 IGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNR-AMAPPWSVWDDQTDSL 129
IGAS G + TATS G +LM E + +A P V+VD+ R + Q D +
Sbjct: 64 IGASWGGLKAMTATSGPGFSLMQENIGFAYMTETPCVVVDIQRGGPSTGQPTMASQGDMM 123
Query: 130 -----SQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNMI 184
S D + + QE+YD +MAF AE +P V+ + +++
Sbjct: 124 QCRWGSHGDYEVIALAPSSVQEMYDFTIMAFNYAEKYRIPVFVMADEIVGHMREKVILHD 183
Query: 185 PQELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGRE 244
E+++ P KP F+ + + + Y + H+E + DV E
Sbjct: 184 NIEIINRKKPEEKPCKKPYPFDK--LIPEMPVFGEGYNV-HITGLTHDE--RGYPDVSPE 238
Query: 245 FGERFGRDYSEMIEKAYID---------DADFVFMGMGSLMGTVKEAVELLRKQGYKVGY 295
++ R I K + DA+ VF+ GS TVK AV LR++G VGY
Sbjct: 239 THDKLVRRIVNKIRKNKDEIIKWEGENLDAEIVFVCYGSPSRTVKHAVRNLREKGLDVGY 298
Query: 296 AKVRWFRPFPREELLEIAESVKGIAVLDRN 325
++ PFP + L ++ K + V + N
Sbjct: 299 IRLITVYPFPDDLLKKL--KAKKVVVPEMN 326
>pir||F75168 2-ketoglutarate ferredoxin oxidoreductase, chain alpha (kora-2)
PAB0346 - Pyrococcus abyssi (strain Orsay)
>gi|5457939|emb|CAB49429.1| (AJ248284) 2-ketoglutarate
ferredoxin oxidoreductase, subunit alpha (korA-2)
[Pyrococcus abyssi]
Length = 385
Score = 101 bits (249), Expect = 2e-20
Identities = 100/336 (29%), Positives = 152/336 (44%), Gaps = 27/336 (8%)
Query: 11 VSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMAAC 70
+ G+ A A A + A + A YPITP + I E +A ++ + + I +E E +++AA
Sbjct: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPLVDGVV--IQMEDEIASIAAI 70
Query: 71 IGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNR----AMAPPWSVWDDQT 126
IGAS GA+ TATS G +LM E + +A PIV+VDV R P D
Sbjct: 71 IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130
Query: 127 DSL--SQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNMI 184
S+ + D + QE +D + AF +AE P +++ A + H E V I
Sbjct: 131 QSIWGTHGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRTPVILLSDAEV-GHMRERV-YI 188
Query: 185 PQ----ELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFR-YKLARAHEEAKKVIK 239
P+ E+V+ LP + L F +P P +R Y H+E + +
Sbjct: 189 PEPDEIEIVNRKLPQNEEEAKL-PFGDPHGDFVPPMPIFGRGYRTYVTGLTHDERGRP-R 246
Query: 240 DVGREFGERFGRDYSEMIEK----------AYIDDADFVFMGMGSLMGTVKEAVELLRKQ 289
V RE ER R E IE+ +DDA+ + G + + A++ LR+
Sbjct: 247 TVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKELREL 306
Query: 290 GYKVGYAKVRWFRPFPREELLEIAESVKGIAVLDRN 325
G K G K+ PF E + +IA V+ I V + N
Sbjct: 307 GIKAGLLKINTIWPFDFELIEKIAGKVERIYVPEMN 342
>pir||H69004 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain
- Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2622136|gb|AAB85529.1| (AE000875) 2-oxoglutarate
oxidoreductase, alpha subunit [Methanobacterium
thermoautotrophicum]
Length = 378
Score = 100 bits (247), Expect = 3e-20
Identities = 93/336 (27%), Positives = 147/336 (43%), Gaps = 30/336 (8%)
Query: 11 VSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMAAC 70
+ GN A A + A + A YPITP T I E++A + E + ++ +E E A+ A
Sbjct: 9 IQGNDACARGAIKAGCRFFAGYPITPSTEIAEEMALLLPR-EGGV-FVQMEDEIGALGAV 66
Query: 71 IGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNR-AMAPPWSVWDDQTDSL 129
IGA +G R TATS G +LM E + +AA P+V+V+V R + + Q+D +
Sbjct: 67 IGAVWSGVRGMTATSGPGFSLMQEHVGYAAMTETPLVIVNVQRGSPSTGQPTMASQSDMM 126
Query: 130 SQR-----DTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNMI 184
R D + + QE +D + AF +AE VP MV+ I+ H E + +
Sbjct: 127 QARWGSHGDYEIIALSPSSVQECFDFTVRAFNLAEEYRVPVMVMGDE-IVGHMREKITIP 185
Query: 185 ----------PQELVDEFLP---PRKPLYSLADFEN--PIAVGALATPADYYEFRYKLAR 229
P +EFLP P + + F + I V L Y
Sbjct: 186 DRVKIRKRRGPSVPPEEFLPFSAPEDGVPEMPAFGDGYRIPVTGLTHDEGGYPDASNPEG 245
Query: 230 AHEEAKKVIKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQ 289
H K++ + R RD +++ +DA + G+ +V AV++ R+
Sbjct: 246 HHRLVKRLCDKILRH------RDRISDVQEELTEDAYITVISYGAPSRSVATAVKMARED 299
Query: 290 GYKVGYAKVRWFRPFPREELLEIAESVKGIAVLDRN 325
G + GY K+ PFP E+ AE + V++ N
Sbjct: 300 GVRAGYLKINTPWPFPETEVRAAAERSGKLLVVEMN 335
>sp|O27112|KORA_METTH 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KETOGLUTARATE
OXIDOREDUCTASE ALPHA CHAIN) (KOR)
(2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT)
Length = 376
Score = 100 bits (247), Expect = 3e-20
Identities = 93/336 (27%), Positives = 147/336 (43%), Gaps = 30/336 (8%)
Query: 11 VSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMAAC 70
+ GN A A + A + A YPITP T I E++A + E + ++ +E E A+ A
Sbjct: 7 IQGNDACARGAIKAGCRFFAGYPITPSTEIAEEMALLLPR-EGGV-FVQMEDEIGALGAV 64
Query: 71 IGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNR-AMAPPWSVWDDQTDSL 129
IGA +G R TATS G +LM E + +AA P+V+V+V R + + Q+D +
Sbjct: 65 IGAVWSGVRGMTATSGPGFSLMQEHVGYAAMTETPLVIVNVQRGSPSTGQPTMASQSDMM 124
Query: 130 SQR-----DTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNMI 184
R D + + QE +D + AF +AE VP MV+ I+ H E + +
Sbjct: 125 QARWGSHGDYEIIALSPSSVQECFDFTVRAFNLAEEYRVPVMVMGDE-IVGHMREKITIP 183
Query: 185 ----------PQELVDEFLP---PRKPLYSLADFEN--PIAVGALATPADYYEFRYKLAR 229
P +EFLP P + + F + I V L Y
Sbjct: 184 DRVKIRKRRGPSVPPEEFLPFSAPEDGVPEMPAFGDGYRIPVTGLTHDEGGYPDASNPEG 243
Query: 230 AHEEAKKVIKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQ 289
H K++ + R RD +++ +DA + G+ +V AV++ R+
Sbjct: 244 HHRLVKRLCDKILRH------RDRISDVQEELTEDAYITVISYGAPSRSVATAVKMARED 297
Query: 290 GYKVGYAKVRWFRPFPREELLEIAESVKGIAVLDRN 325
G + GY K+ PFP E+ AE + V++ N
Sbjct: 298 GVRAGYLKINTPWPFPETEVRAAAERSGKLLVVEMN 333
>pir||T43258 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) pfoA precursor,
hydrogenosomal - Trichomonas vaginalis
>gi|622958|gb|AAA85494.1| (U16822) pyruvate:ferredoxin
oxidoreductas proprotein [Trichomonas vaginalis]
Length = 1157
Score = 100 bits (246), Expect = 4e-20
Identities = 109/386 (28%), Positives = 166/386 (42%), Gaps = 29/386 (7%)
Query: 8 KKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADI-----QYIPVES 62
K++ AA +V + + YPITP T++ E + +IA G +I ++S
Sbjct: 7 KRIPGDGNTAATSVAYQLSETSFIYPITPATTMGELVDAWIAQGRKNIWGNKVHMAMMQS 66
Query: 63 EHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMA-PPWSV 121
E A AA GA+A GA T T++QG LM ++ G P V R +A S+
Sbjct: 67 EGGAAAAVHGATAVGALCATFTASQGALLMIPDMYKIIGEMCPAVFHISARCIATSALSI 126
Query: 122 WDDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSH---TY 178
++D D + R TG ++ QE +D +A +P + F SH TY
Sbjct: 127 YNDHGDIYACRATGMPILFSNGVQEAHDLAAVAHLTTIHTGLPFIHTFDGFRTSHEINTY 186
Query: 179 EIVNMIPQELVDEFLPPRKPLYSLADF-------ENPIAVGALATPADYYEFRYKLARAH 231
E EL +E L P +LA F E+P G + P ++ KL +
Sbjct: 187 E-------ELDNETLWPLIDQKALAAFRARSLNPEHPSERGTICGPEYVWQMHEKLRKPF 239
Query: 232 EEAKKVIKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGY 291
+ ++ + + G++ GR Y + + A D + V + MGS V+E + +
Sbjct: 240 QALPTEVEKMMKALGDKTGR-YYKPYQYAGPRDPENVIIMMGSGCDPVEEYI--TEHPEF 296
Query: 292 KVGYAKVRWFRPFPREEL-LEIAESVKGIAVLDRNFS-FGQEGILFTEAKGALYNNGARP 349
K G KV FRPF E I SVK I VLD+ G LF + AL
Sbjct: 297 KTGLIKVHLFRPFSVEMFNAAIPASVKKICVLDKVVDPTGPREPLFEDVAAALIGERNVK 356
Query: 350 IMKNYIVGLGGRDFTVSDVKAIAEDM 375
I+ G+ RDF V+AI +++
Sbjct: 357 IIGGR-YGISSRDFAPVHVEAIVKNL 381
>gb|AAD55754.1|AF132546_1 (AF132546) pyruvate:ferredoxin oxidoreductase [Spironucleus
barkhanus]
Length = 1182
Score = 94.0 bits (230), Expect = 3e-18
Identities = 103/391 (26%), Positives = 170/391 (43%), Gaps = 40/391 (10%)
Query: 11 VSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADI-----QYIPVESEHS 65
+ GN AAA+ + + +PI+P + + E + E+ + G + + + E
Sbjct: 1 IDGNTAAAH-IAYYLCDNSLIFPISPSSPMAELVDEWASKGRLNAFDQVHRVTELNHEGG 59
Query: 66 AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAP-PWSVWDD 124
A A GA G+ T T++QGL LM L+ A LP V+ R +A S+ D
Sbjct: 60 AAGALHGALLNGSLSSTYTASQGLLLMIPNLYKMAAEHLPGVLHVAARTIATHSLSIHGD 119
Query: 125 QTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNMI 184
+D ++ + TG + + QE D L+A A + P + + SHT + V +I
Sbjct: 120 HSDIMAIKQTGISILVSPDVQEAMDFALVAHIAAINADTPFIHAFDGYRTSHTIKKVEVI 179
Query: 185 PQELVDEFLPPRKPLYSLADF-------ENPIAVGALATP--------ADYYEFRYKLAR 229
+ + F+P K +A+F + P A G+ P AD + L
Sbjct: 180 SYDKIKPFVPYEK----IAEFRHKSLNSQRPEAYGSCMGPPVWMQSQEADNLHYSKILGH 235
Query: 230 AHEEAKKVIKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQ 289
+ V K GR++ E+I+ DA V + MGS TV+E V+ L Q
Sbjct: 236 FEDAFVTVEKITGRKY---------EVIQYHGCADATDVIVIMGSGCITVRETVDYLNAQ 286
Query: 290 GYKVGYAKVRWFRPFPREELL-EIAESVKGIAVLDRNFSFGQEG-ILFTEAKGALYNNGA 347
G KVG + FRPFP ++ ++ S + I LDR G + + L ++
Sbjct: 287 GRKVGAIFINLFRPFPSAHIIAKLPVSCQRICTLDRCKEPESTGEPIKLDVMSCLISSRR 346
Query: 348 RPIMKNYIVGLGG---RDFTVSDVKAIAEDM 375
++ I G G +DFT +DV A+ +++
Sbjct: 347 IQTIQTLIGGRYGQSSKDFTPADVIAVYDNL 377
>sp|O26800|VORB_METTH KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORB (VOR) (2-OXOISOVALERATE
OXIDOREDUCTASE BETA CHAIN) (2-OXOISOVALERATE-FERREDOXIN
OXIDOREDUCTASE BETA SUBUNIT)
Length = 352
Score = 92.1 bits (225), Expect = 1e-17
Identities = 87/333 (26%), Positives = 142/333 (42%), Gaps = 38/333 (11%)
Query: 9 KVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMA 68
++V GN A ++A YPITP + I+ + + + +++ ESE +A+
Sbjct: 4 QMVKGNTAVIIGAMYAGCDCYFGYPITPASEILHEASRYFPM--VGRKFVQAESEEAAIN 61
Query: 69 ACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQTDS 128
GA+A G RV TA+S G++L E + + AGA LP V+VDV RA ++ +Q D
Sbjct: 62 MVYGAAAAGHRVMTASSGPGISLKQEGISFLAGAELPAVIVDVMRAGPGLGNIGPEQGDY 121
Query: 129 LSQRDTGW------MQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVN 182
G M + QE+ D + AF++A+ P +V+ A +L E +
Sbjct: 122 NQIVKGGGHGNYRNMVLAPSSVQEMCDLTMEAFELADKYRNPVVVLTDA-VLGQMAEPLR 180
Query: 183 MIPQELVDEFLPPRKPLYSLADFENPIAVGALATPA-----DYYEFRYKLARAHEEAKKV 237
P+E V+ +P S A N + L T + EF + L + +
Sbjct: 181 -FPEEAVE-----HRPDTSWAVCGNRETMKNLVTSIFLDFDELEEFNFYLQEKYARIE-- 232
Query: 238 IKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAK 297
+ E+ +DDA+ V + G + AVE R +G VG +
Sbjct: 233 --------------ENEVRYEEYLVDDAEIVMVAYGISSRVARSAVETARAEGINVGLLR 278
Query: 298 VRWFRPFPREELLEIAESVKGIAVLDRNFSFGQ 330
PFP + + E+A+ G + S GQ
Sbjct: 279 PITLFPFPSDRIRELADG--GCRFISVEMSSGQ 309
>pir||A69194 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2621790|gb|AAB85209.1| (AE000849) 2-oxoisovalerate
oxidoreductase, beta subunit [Methanobacterium
thermoautotrophicum]
Length = 348
Score = 91.7 bits (224), Expect = 1e-17
Identities = 87/332 (26%), Positives = 141/332 (42%), Gaps = 38/332 (11%)
Query: 10 VVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMAA 69
+V GN A ++A YPITP + I+ + + + +++ ESE +A+
Sbjct: 1 MVKGNTAVIIGAMYAGCDCYFGYPITPASEILHEASRYFPM--VGRKFVQAESEEAAINM 58
Query: 70 CIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQTDSL 129
GA+A G RV TA+S G++L E + + AGA LP V+VDV RA ++ +Q D
Sbjct: 59 VYGAAAAGHRVMTASSGPGISLKQEGISFLAGAELPAVIVDVMRAGPGLGNIGPEQGDYN 118
Query: 130 SQRDTGW------MQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNM 183
G M + QE+ D + AF++A+ P +V+ A +L E +
Sbjct: 119 QIVKGGGHGNYRNMVLAPSSVQEMCDLTMEAFELADKYRNPVVVLTDA-VLGQMAEPLR- 176
Query: 184 IPQELVDEFLPPRKPLYSLADFENPIAVGALATPA-----DYYEFRYKLARAHEEAKKVI 238
P+E V+ +P S A N + L T + EF + L + +
Sbjct: 177 FPEEAVE-----HRPDTSWAVCGNRETMKNLVTSIFLDFDELEEFNFYLQEKYARIE--- 228
Query: 239 KDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKV 298
+ E+ +DDA+ V + G + AVE R +G VG +
Sbjct: 229 -------------ENEVRYEEYLVDDAEIVMVAYGISSRVARSAVETARAEGINVGLLRP 275
Query: 299 RWFRPFPREELLEIAESVKGIAVLDRNFSFGQ 330
PFP + + E+A+ G + S GQ
Sbjct: 276 ITLFPFPSDRIRELADG--GCRFISVEMSSGQ 305
>pir||H81399 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain
Cj0536 [similarity] - Campylobacter jejuni (strain NCTC
11168) >gi|6968004|emb|CAB75172.1| (AL139075) OORA
subunit of 2-oxoglutarate:acceptor oxidoreductase
[Campylobacter jejuni]
Length = 374
Score = 91.3 bits (223), Expect = 2e-17
Identities = 90/370 (24%), Positives = 164/370 (44%), Gaps = 30/370 (8%)
Query: 10 VVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMAA 69
+ +GN A A + + YPITP + I +++ + + +I +E E S ++
Sbjct: 5 IATGNVLIAKAAIDCGCKFFGGYPITPSSEIAHELSHMLPANDGT--FIQMEDEISGISV 62
Query: 70 CIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNR---AMAPPWSVWDD-- 124
IGA+ +G + TA+S G++L E + A A +P+V+V+V R + P V
Sbjct: 63 AIGAAMSGVKSMTASSGPGISLKAEQIGLAFIAEIPLVIVNVMRGGPSTGLPTRVAQGDL 122
Query: 125 -QTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVN- 182
Q + + D + + +E Y + AF +AE P + ++ T +N
Sbjct: 123 FQAKAPTHGDFASIAIAPASLEEAYTETIRAFNLAEKYMTPVFL-----LMDETVGHMNG 177
Query: 183 -MIPQELVDEFLPPRKPLYSLADFENPIAVGAL--ATPADYYE-FRYKLARAH------- 231
+ +L D + RK P A G AT ++ +RY + H
Sbjct: 178 KAVLPDLKDIKVYNRKKFEGDKKDYKPYAAGENEPATLNPFFTGYRYHVTGLHHGDIGFP 237
Query: 232 -EEAKKVIKDVGREFGE-RFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQ 289
E+ V K++ R G+ + ++ E+ +DDA+F+ + GS+ + KEA++ LR+Q
Sbjct: 238 TEDGVIVKKNMERLIGKIKNNQEDICTYEEYMLDDAEFLIIAYGSVSRSAKEAIQRLREQ 297
Query: 290 GYKVGYAKVRWFRPFPREELLEIAESVKGIAVLDRNFSFGQEGILFTEAKG---ALYNNG 346
G KVG + P +++ E+ K + V + N E I ++ +L+
Sbjct: 298 GIKVGLFRPITLYPVAEKKIAEVVSKFKKVMVSELNMGQYLEEIERVTSRRDFISLHRAN 357
Query: 347 ARPIMKNYIV 356
RPI + I+
Sbjct: 358 GRPITPSEII 367
>pir||T18528 probable pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) -
Giardia intestinalis >gi|960283|gb|AAA74894.1| (L27221)
pyruvate:ferredoxin oxidoreductase [Giardia
intestinalis]
Length = 1253
Score = 88.9 bits (217), Expect = 9e-17
Identities = 94/360 (26%), Positives = 151/360 (41%), Gaps = 16/360 (4%)
Query: 17 AAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADI--QYIPVE---SEHSAMAACI 71
A +++ + A +PITP + + E I ++ A G+ +I + V SE A+ C
Sbjct: 18 ATSMMVYRLIDFTAIFPITPSSVMAEMIEQYAAQGKKNIFGNVVTVRQAWSELGAIGTCH 77
Query: 72 GASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMA-PPWSVWDDQTDSLS 130
GA+ GA T +S+QG+ LM L+ AG R+P V+ R + S+ D TD +
Sbjct: 78 GAATAGALTATFSSSQGVLLMISNLYHMAGERIPFVLHVATRTVGMAATSLATDHTDVYA 137
Query: 131 QRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIVNMIPQEL-V 189
T + N QE YD L+A A V + +SH +E + + + +
Sbjct: 138 IEGTNMCALSSCNVQECYDMSLVAHTTATNVQAAFCHFFEGYRVSHQFETIQVFKDDADI 197
Query: 190 DEFLP----PRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGREF 245
+FL + + D + PIA + + + I++
Sbjct: 198 KDFLSEDQLAKWRSENAMDTDRPIASNIGLGGEIHMQIVESQGAVFDSIPYRIEEAFDLL 257
Query: 246 GERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVE-LLRKQGYKVGYAKVRWFRPF 304
+ GR Y E D V + MG+ T + V+ L+ ++ +VG+ +VR FRPF
Sbjct: 258 HRKTGRRY-HCFEYFGHPTPDVVVVVMGATSLTFENVVDALVNRENRRVGFVRVRLFRPF 316
Query: 305 PREELLE-IAESVKGIAVLDRNFS-FGQEGILFTEAKGALYNNGARPIMKNYI-VGLGGR 361
E I +S K + LDR G L+ E AL G KN + + GGR
Sbjct: 317 SIELFSNAIPKSAKVVVALDRAPELLNAGGTLYRETLAALMKTGRLGAGKNSVRLVAGGR 376
>gb|AAD55757.1|AF146519_1 (AF146519) putative pyruvate:ferredoxin oxidoreductase 2 [Giardia
intestinalis]
Length = 512
Score = 88.2 bits (215), Expect = 2e-16
Identities = 99/332 (29%), Positives = 144/332 (42%), Gaps = 22/332 (6%)
Query: 60 VESEHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAP-P 118
+ SE A C S TG T T++QGL LM ++ AG LP V R +A
Sbjct: 1 MNSEGLLQAPCTELSDTGLLASTYTASQGLLLMIPNMYKMAGEHLPAVFHVAARTIATHS 60
Query: 119 WSVWDDQTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTY 178
SV D D ++ R TG +E+ QE D + A A + P + F SHT
Sbjct: 61 LSVHGDHADIMAVRQTGCTIMVSEDIQEAMDMAIAAHLTAIYSSYPVVHAFDGFRTSHTI 120
Query: 179 EIVNMIPQELVD-EFLPPRKPLYSLADF-------ENPIAVGALATPADYYEFRYKLARA 230
+ V EL+D E L P P + F ++P G+ P + + +
Sbjct: 121 KKV-----ELIDYEHLRPHVPYDEIEAFRQKSLSPQHPEMRGSCQGPPIWMQAGEADNKH 175
Query: 231 HEEAKKVIKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQG 290
+ E ++ + E GR Y + DA V + MGS TV E VE L ++G
Sbjct: 176 YAEIPGHVERAFEKVREITGRSY-KFFNYFGAPDATAVVIIMGSGYLTVHEVVEYLVERG 234
Query: 291 YKVGYAKVRWFRPFPREELLE-IAESVKGIAVLD--RNFSFGQEGILFTEAKGALYNN-- 345
KVG V FRPF ++LLE I S + I V++ + G E L + ALY+
Sbjct: 235 DKVGVVCVHLFRPFCGDKLLEAIPTSCRRICVMEKAKEIMAGAEP-LRLDVIEALYSGNR 293
Query: 346 -GARPIMKNYIVGLGGRDFTVSDVKAIAEDMK 376
A + I GL +DF +D AI+ +++
Sbjct: 294 LSAVTTVIGGIFGLSSKDFNTADAFAISRNLQ 325
>pir||H72323 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain
TM0878 [similarity] - Thermotoga maritima (strain MSB8)
>gi|4981412|gb|AAD35959.1|AE001753_15 (AE001753)
pyruvate:ferredoxin 2-oxidoreductase-related protein
[Thermotoga maritima]
Length = 386
Score = 86.2 bits (210), Expect = 6e-16
Identities = 85/344 (24%), Positives = 142/344 (40%), Gaps = 31/344 (9%)
Query: 6 PIKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHS 65
P + GN A A + A + A YPITP T I E +A + + ++ +E E +
Sbjct: 4 PEMMFLQGNEACALGAIKAGCRFFAGYPITPSTEIAEVMARELP--KVGGVFVQMEDEIA 61
Query: 66 AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNR----AMAPPWSV 121
+ AA +GAS G + TATS G +L+ E++ +A P V +V R P
Sbjct: 62 SAAAVVGASLAGVKSMTATSGPGFSLIQEVIGYAIMTETPCVFANVMRLGPSTGLPTKPA 121
Query: 122 WDD--QTDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYE 179
D QT + D + Y + EVY ++ AF +AE P + + A +L H E
Sbjct: 122 QGDIMQTRWGTHGDHAIIALYPSSVAEVYRYIITAFNLAEEYRTPVVFLMDA-MLGHMRE 180
Query: 180 IVNMIPQELVDEFLPPR--KPLYSLADFENPIAVGALATPADYYEFRYKLARAH------ 231
+ P + + F+ R + D P + A P + + H
Sbjct: 181 --SFYPPKDEELFIIERLKDTSFGEEDLFVPFSESEYAEPTPFPMAEMGKTKFHVSGLVH 238
Query: 232 ----------EEAKKVIKDVGREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKE 281
+ A+K+I+ + + R D E+ +DA+ + + G + + +
Sbjct: 239 DESGFPLSSPDAAEKLIRRLTNKI--RLHADEIAFYEEYETEDAEILVVAYGIVARSAMK 296
Query: 282 AVELLRKQGYKVGYAKVRWFRPFPREELLEIAESVKGIAVLDRN 325
AV++ R+ KVG K P P ++AE V I + + N
Sbjct: 297 AVKIARRDRIKVGLFKPITIWPAPVSRFRKLAEKVNTIVIAEMN 340
>pir||E64593 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain -
Helicobacter pylori (strain 26695)
>gi|2313707|gb|AAD07654.1| (AE000572) ferredoxin
oxidoreductase, alpha subunit [Helicobacter pylori
26695]
Length = 375
Score = 85.8 bits (209), Expect = 8e-16
Identities = 86/340 (25%), Positives = 153/340 (44%), Gaps = 25/340 (7%)
Query: 7 IKKVVS-GNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHS 65
+++++S GN A A + + YPITP + I+ ++ +A + +I +E E S
Sbjct: 1 MREIISDGNELVAKAAIEVGCRFFGGYPITPSSDIMHAMS--VALPKCGGHFIQMEDEIS 58
Query: 66 AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNR---AMAPPWSVW 122
++ +GAS +G + TA+S G++L E + ++ A +P+V+ DV R + P V
Sbjct: 59 GISVSLGASMSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMRSGPSTGMPTRVA 118
Query: 123 DDQTDSLSQRDTGWMQFYA---ENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYE 179
+ L G + A N +E Y + AF +AE + P ++ + H Y
Sbjct: 119 QGDVNFLRHPIHGDFKAVALAPANLEEAYTETVRAFNLAEMLMTPVFLLMDETV-GHMYG 177
Query: 180 IVNMIPQELVDEFLPPRKPLYSLADFENPIAVG----ALATPADYYEFRYKLARAH---- 231
V + E V + RK P V A+ P + +RY ++ H
Sbjct: 178 KVQIPDLEEVQKMTINRKEFLGDKKDYKPYGVAQDEPAVLNPF-FKGYRYHVSGLHHGPI 236
Query: 232 ----EEAKKVIKDVGREFGE-RFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELL 286
E+AK + R F + +D E+ ++ A+ V + GS+ VKEA++
Sbjct: 237 GFPTEDAKIGGDLIDRLFNKIESKQDIINENEEMDLEGAEIVVIAYGSVSLAVKEALKDY 296
Query: 287 RKQG-YKVGYAKVRWFRPFPREELLEIAESVKGIAVLDRN 325
K+ KVG+ + + P P + L EI + + I V++ N
Sbjct: 297 HKESKQKVGFFRPKTLWPSPAKRLKEIGDKYEKILVIELN 336
>gi|11498080 2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA)
[Archaeoglobus fulgidus]
>gi|6685587|sp|O29781|KORA_ARCFU 2-OXOGLUTARATE SYNTHASE
SUBUNIT KORA (2-KETOGLUTARATE OXIDOREDUCTASE ALPHA
CHAIN) (KOR) (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE
ALPHA SUBUNIT) >gi|7433685|pir||E69308
2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-)
alpha chain korA - Archaeoglobus fulgidus
>gi|2650159|gb|AAB90768.1| (AE001072) 2-ketoglutarate
ferredoxin oxidoreductase, subunit alpha (korA)
[Archaeoglobus fulgidus]
Length = 346
Score = 83.5 bits (203), Expect = 4e-15
Identities = 82/324 (25%), Positives = 145/324 (44%), Gaps = 27/324 (8%)
Query: 9 KVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHSAMA 68
+++ GN AA ++A A YPITP + I +AE + +I +E E ++++
Sbjct: 4 ELIQGNEAAVRGAINAGCNFFAGYPITPSSEIAHGMAELLPKFGG--VFIQMEDEIASIS 61
Query: 69 ACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSV--WDDQT 126
A IGAS GA TATS G +LM E + +AA P+V+ +V RA P + Q
Sbjct: 62 AVIGASMAGAVAMTATSGPGFSLMQEGMGYAAITESPVVIFNVMRA-GPSTGIPTAPSQG 120
Query: 127 DSLSQR-----DTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYEIV 181
D++ R D + + +++Y + AFK+A + P +V+ S I+ H E V
Sbjct: 121 DAMQARYGSHGDYPIVVLAPASVKDMYYLTVEAFKIAFRFSTPVIVL-SDEIVGHMRESV 179
Query: 182 NMIPQELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDV 241
+ P ++ + K +L D G + T EE +K+++ +
Sbjct: 180 ALPPLGEIESY---EKRAKNLIDGRRRHRTGLVHTENGL------PTTDLEEYEKLLRLL 230
Query: 242 GREFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWF 301
+F D+ M+ + + +F+ GS K + +LL ++G G K+
Sbjct: 231 FAKFD-----DFRPMVR--FEGEEGVLFVAYGSSYRLAKSSAKLLAEKGVSAGILKLESL 283
Query: 302 RPFPREELLEIAESVKGIAVLDRN 325
PFP + + ++ + V + N
Sbjct: 284 FPFPEDAVRRYSKKADLVVVPEMN 307
>pir||G71919 chain of 2-oxoglutarate oxidoreductase - Helicobacter pylori
(strain J99) >gi|4155084|gb|AAD06119.1| (AE001486)
SUBUNIT OF 2-OXOGLUTARATE OXIDOREDUCTASE [Helicobacter
pylori J99]
Length = 375
Score = 83.5 bits (203), Expect = 4e-15
Identities = 85/340 (25%), Positives = 152/340 (44%), Gaps = 25/340 (7%)
Query: 7 IKKVVS-GNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHS 65
+++++S GN A A + + YPITP + I+ ++ +A + +I +E E S
Sbjct: 1 MREIISDGNELVAKAAIEVGCRFFGGYPITPSSDIMHAMS--VALPKCGGHFIQMEDEIS 58
Query: 66 AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNR---AMAPPWSVW 122
++ +GAS +G + TA+S G++L E + ++ A +P+V+ DV R + P V
Sbjct: 59 GISVSLGASMSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMRSGPSTGMPTRVA 118
Query: 123 DDQTDSLSQRDTGWMQFYA---ENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYE 179
+ L G + A N +E Y + AF +AE + P ++ + H Y
Sbjct: 119 QGDVNFLRHPIHGDFKAVALAPANLEEAYTETVRAFNLAEMLMTPVFLLMDETV-GHMYG 177
Query: 180 IVNMIPQELVDEFLPPRKPLYSLADFENPIAVG----ALATPADYYEFRYKLARAH---- 231
V + E V + RK P V A+ P + +RY ++ H
Sbjct: 178 KVQIPDLEEVQKMTINRKEFAGDKKDYKPYGVAQDEPAVLNPF-FKGYRYHVSGLHHGPI 236
Query: 232 ----EEAKKVIKDVGREFGE-RFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELL 286
E+AK + R F + +D E+ ++ + V + GS+ VKEA++
Sbjct: 237 GFPTEDAKIGGDLIDRLFHKIESKQDIINENEEMDLEGTEIVIIAYGSVSLAVKEALKDY 296
Query: 287 RKQG-YKVGYAKVRWFRPFPREELLEIAESVKGIAVLDRN 325
K+ KVG+ + + P P + L EI + + I V++ N
Sbjct: 297 NKESKQKVGFFRPKTLWPSPAKRLKEIGDKYEKILVIELN 336
>pir||A72627 probable 2-oxoacid--ferredoxin oxidoreductase, alpha chain APE1473
- Aeropyrum pernix (strain K1)
>gi|5105157|dbj|BAA80471.1| (AP000061) 616aa long
hypothetical 2-oxoacid--ferredoxin oxidoreductase ,
alpha chain [Aeropyrum pernix]
Length = 616
Score = 83.5 bits (203), Expect = 4e-15
Identities = 103/420 (24%), Positives = 178/420 (41%), Gaps = 73/420 (17%)
Query: 10 VVSGNYAAAYAVLHARVQVVAAYPITPQT------------SIIEKIAEFIANGEADIQY 57
V +GN A + + V+ YPITP + SI +AE + + +
Sbjct: 215 VATGNDLVAMGKIVGGLGVITYYPITPSSDEALYVEKHSYISIDGPLAEKLGYDKIAVAI 274
Query: 58 IPVESEHSAMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRA--- 114
+ +E E +++ A +GA+A GAR T TS G +LM+E + A A +P+V+ RA
Sbjct: 275 VQMEDELASINAVLGAAAAGARASTTTSGPGFSLMNEAVSLAVEAEIPVVVTLWMRAGPS 334
Query: 115 -MAPPWSVWDDQTDSL--SQRDTGWMQFYAENNQEVYDGVLMAFKVAETVNVPAMVVESA 171
P + D S+ D + + ++ E + + AF AE P + +
Sbjct: 335 TGMPTRTGQQDLLHSIFSGHGDAPKIVLASGDHVEAFYDAIKAFNWAEEFQTPVIHLLDK 394
Query: 172 FILSHTYEIVNMIPQELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEF-------- 223
++ S + ++ P + P+ +NP PADY +
Sbjct: 395 YLASSMVSLAR-------EDLDPSKVPITRGKLLDNP--------PADYRRYEVVEDGIS 439
Query: 224 -RYKLARA--------HEEAKKVIKD-VGREF----GERFGRDYSEMI---EKAYI---D 263
R +L A H+E +D V RE ER + E I EKA +
Sbjct: 440 PRARLGSATMVITGLEHDEYGYATEDPVMREIMMFKRERKFKVIEERIPDEEKAVLHGDS 499
Query: 264 DADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWFRPFPREELLEIAESVKGIAVLD 323
+A + GS + EA+E+LR +G + +A+VR PFP + E+ E V+ + +++
Sbjct: 500 EASVALVSFGSTKQPILEALEMLRDEGVRARFAQVRLLYPFPGRLVEEMLEGVEKVIMVE 559
Query: 324 RNFSFGQEGILFTEAKGALYNNGARPIMKNYIVGLGGRDFTVSDVKAIAEDMKKVIESGK 383
+N GQ +L + +P + IV + GR +V A +K+++E+G+
Sbjct: 560 QNL-LGQLAMLLRA------HTSIKP--DSSIVKINGRPLYSFEV---AGAVKRILETGE 607
>gb|AAC38211.1| (AF021094) OorA subunit of 2-oxoglutarate:acceptor oxidoreductase
[Helicobacter pylori]
Length = 371
Score = 82.3 bits (200), Expect = 9e-15
Identities = 85/340 (25%), Positives = 151/340 (44%), Gaps = 25/340 (7%)
Query: 7 IKKVVS-GNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHS 65
+++++S GN A A + + YPITP + I+ ++ + N +I +E E S
Sbjct: 1 MREIISDGNELVAKAAIEVGCRFFGGYPITPSSDIMHAMSVALPNCGG--HFIQMEDEIS 58
Query: 66 AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNR---AMAPPWSVW 122
++ +GAS +G + TA+S G++L E + ++ A +P+V+ DV R + P V
Sbjct: 59 GISVSLGASMSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMRSGPSTGMPTRVD 118
Query: 123 DDQTDSLSQRDTGWMQFYA---ENNQEVYDGVLMAFKVAETVNVPAMVVESAFILSHTYE 179
+ L G + A + +E Y AF +AE + P ++ + H Y
Sbjct: 119 QGDVNFLRHPIHGDFKAVALAPASLEEAYTETARAFNLAEMLMTPVFLLMDETV-GHMYG 177
Query: 180 IVNMIPQELVDEFLPPRKPLYSLADFENPIAVG----ALATPADYYEFRYKLARAH---- 231
V + E V + RK P V A+ P + +RY ++ H
Sbjct: 178 KVQIPDLEEVQKTTINRKEFVGDKKDYKPYGVAQDEPAVLNPF-FKGYRYHVSGLHHGPI 236
Query: 232 ----EEAKKVIKDVGREFGE-RFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELL 286
E+AK + R F + +D E+ ++ A+ V + GS+ VKEA++
Sbjct: 237 GFPTEDAKIGGDLIDRLFNKIESKQDIINENEEMDLEGAEIVIIAYGSVSLAVKEALKDY 296
Query: 287 RKQ-GYKVGYAKVRWFRPFPREELLEIAESVKGIAVLDRN 325
K+ KVG+ + + P P + L EI + + I V++ N
Sbjct: 297 HKESNQKVGFFRPKTLWPSPAKRLKEIGDKYEKILVIELN 336
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.320 0.136 0.395
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 141551935
Number of Sequences: 2977
Number of extensions: 5740656
Number of successful extensions: 14943
Number of sequences better than 1.0e-10: 71
Number of HSP's better than 0.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 14712
Number of HSP's gapped (non-prelim): 81
length of query: 395
length of database: 189,106,746
effective HSP length: 57
effective length of query: 338
effective length of database: 154,992,987
effective search space: 52387629606
effective search space used: 52387629606
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 166 (69.1 bits)