BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1475 (porA) DE:PYRUVATE SYNTHASE SUBUNIT PORA (EC 1.2.7.1) (PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR) (395 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||G75046 pyruvate synthase (EC 1.2.7.1) alpha chain PAB1475 -... 786 0.0 pir||E71114 probable ferredoxin oxidoreductase alpha-2 subunit -... 755 0.0 sp|O73986|PORA_PYRHO PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX... 755 0.0 sp|Q51804|PORA_PYRFU PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX... 727 0.0 gb|AAF91264.1|AF230199_6 (AF230199) pyruvate oxidoreductase alph... 430 e-119 sp|P56810|PORA_METTH PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX... 414 e-114 sp|Q57715|PORA_METJA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX... 411 e-114 sp|Q51801|VORA_PYRFU KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA... 392 e-108 pir||A71114 probable ferredoxin oxidoreductase alpha subunit - P... 388 e-107 sp|O58413|VORA_PYRHO KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA... 388 e-107 pir||B75047 probable 2-oxoisovalerate--ferredoxin oxidoreductase... 383 e-105 emb|CAA59457.1| (X85171) alpha subunit of pyruvate ferredoxin ox... 340 2e-92 sp|O05651|PORA_THEMA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX... 340 2e-92 emb|CAC11767.1| (AL445064) probable 2-ketovalerate ferredoxin ox... 326 3e-88 gi|11499291 pyruvate ferredoxin oxidoreductase, subunit alpha (p... 322 5e-87 gb|AAK41454.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin... 308 6e-83 gb|AAK42867.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin... 282 5e-75 pir||H71857 pyruvate ferrodoxin oxidoreductase - Helicobacter py... 277 2e-73 pir||F64658 pyruvate synthase (EC 1.2.7.1) alpha chain - Helicob... 275 6e-73 gb|AAC02293.1| (AF013980) pyruvate:ferredoxin oxidoreductase alp... 273 2e-72 gb|AAK42308.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin... 264 2e-69 pir||S74041 pyruvate synthase (EC 1.2.7.1) alpha chain - Sulfolo... 264 2e-69 gi|11499635 2-ketoisovalerate ferredoxin oxidoreductase, subunit... 243 3e-63 gb|AAC38206.1| (AF021092) PorA subunit of pyruvate:flavodoxin ox... 230 2e-59 emb|CAB43933.1| (Y17726) pyruvate ferredoxin oxidoreductase [Clo... 165 9e-40 gb|AAD55756.1|AF132673_1 (AF132673) pyruvate:ferredoxin oxidored... 162 5e-39 emb|CAB43935.1| (Y17727) pyruvate ferredoxin oxidoreductase [Clo... 159 7e-38 pir||A81294 pyruvate-flavodoxin oxidoreductase Cj1476c [imported... 151 2e-35 sp|P19543|NIFJ_ENTAG PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|4690... 150 3e-35 sp|P03833|NIFJ_KLEPN PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|4382... 148 1e-34 pir||QQKBFP pyruvate (flavodoxin) dehydrogenase nifJ (EC 1.2.99.... 148 1e-34 pir||G71262 probable pyruvate (flavodoxin) dehydrogenase (EC 1.2... 145 7e-34 gb|AAC83148.1| (AF061850) putative pyruvate oxidoreductase; POR ... 143 3e-33 emb|CAA70873.1| (Y09702) pyruvate-ferredoxin oxidoreductase [Des... 138 9e-32 pdb|1B0P|A Chain A, Crystal Structure Of Pyruvate-Ferredoxin Oxi... 138 9e-32 emb|CAA57480.1| (X81893) nifJ [Enterobacter agglomerans] 138 1e-31 pir||C70403 ferredoxin oxidoreductase alpha subunit - Aquifex ae... 138 1e-31 dbj|BAA95605.1| (AB042412) pyruvate:ferredoxin oxidoreductase al... 138 1e-31 sp|P52647|NIFJ_ECOLI PROBABLE PYRUVATE-FLAVODOXIN OXIDOREDUCTASE... 134 1e-30 sp|P52965|NIFJ_SYNY3 PUTATIVE PYRUVATE-FLAVODOXIN OXIDOREDUCTASE... 134 2e-30 emb|CAB43934.1| (Y17727) pyruvate ferredoxin oxidoreductase [Clo... 133 3e-30 pir||F82447 pyruvate-flavoredoxin oxidoreductase VCA0530 [import... 130 3e-29 pir||B70400 ferredoxin oxidoreductase alpha subunit - Aquifex ae... 129 4e-29 sp|Q06879|NIFJ_ANASP PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|2126... 123 2e-27 gb|AAD55754.1|AF132546_1 (AF132546) pyruvate:ferredoxin oxidored... 119 5e-26 dbj|BAB12024.1| (AB021127) pyruvate:NADP+ oxidoreductase [Euglen... 115 7e-25 gb|AAB49653.1| (U30149) pyruvate:ferredoxin oxidoreductase [Enta... 115 9e-25 sp|Q53046|NIFJ_RHORU PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|6288... 113 4e-24 pir||S70963 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) - ... 113 4e-24 pir||H72214 hypothetical protein TM1759 - Thermotoga maritima (s... 112 8e-24 pir||T43259 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) pf... 111 1e-23 pir||S58236 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) - ... 109 4e-23 pir||T43258 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) pf... 109 5e-23 pir||C75168 2-ketoglutarate ferredoxin oxidoreductase, chain alp... 108 2e-22 pir||B71047 probable ferredoxin oxidoreductase alpha subunit - P... 105 1e-21 pir||T18528 probable pyruvate (flavodoxin) dehydrogenase (EC 1.2... 103 3e-21 pir||A69194 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al... 98 2e-19 sp|O26800|VORB_METTH KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORB... 98 2e-19 pir||H69004 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.... 94 2e-18 sp|O27112|KORA_METTH 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KET... 94 2e-18 gb|AAD55757.1|AF146519_1 (AF146519) putative pyruvate:ferredoxin... 90 3e-17 pir||F75168 2-ketoglutarate ferredoxin oxidoreductase, chain alp... 89 7e-17 pir||F71046 probable ferredoxin oxidoreductase alpha subunit - P... 87 3e-16 sp|Q57724|KORA_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KET... 85 1e-15 emb|CAA34396.1| (X16345) nifJ [Klebsiella pneumoniae] 80 3e-14 pir||E64593 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al... 72 1e-11 gb|AAC38211.1| (AF021094) OorA subunit of 2-oxoglutarate:accepto... 71 2e-11 emb|CAA25502.1| (X01007) URF [Klebsiella pneumoniae] 71 3e-11 pir||G71919 chain of 2-oxoglutarate oxidoreductase - Helicobacte... 69 6e-11 >pir||G75046 pyruvate synthase (EC 1.2.7.1) alpha chain PAB1475 - Pyrococcus abyssi (strain Orsay) >gi|5458781|emb|CAB50268.1| (AJ248287) PYRUVATE SYNTHASE SUBUNIT PORA (EC 1.2.7.1) (PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR) [Pyrococcus abyssi] Length = 395 Score = 786 bits (2007), Expect = 0.0 Identities = 395/395 (100%), Positives = 395/395 (100%) Query: 1 MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEH 60 MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEH Sbjct: 1 MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEH 60 Query: 61 SAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWND 120 SAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWND Sbjct: 61 SAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWND 120 Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE Sbjct: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 Query: 181 IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAF 240 IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAF Sbjct: 181 IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAF 240 Query: 241 AEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300 AEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP Sbjct: 241 AEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300 Query: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV 360 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV Sbjct: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV 360 Query: 361 TFNQLDEALSIAKEALEKGKVEKPIHWIGLRKELL 395 TFNQLDEALSIAKEALEKGKVEKPIHWIGLRKELL Sbjct: 361 TFNQLDEALSIAKEALEKGKVEKPIHWIGLRKELL 395 >pir||E71114 probable ferredoxin oxidoreductase alpha-2 subunit - Pyrococcus horikoshii >gi|3257092|dbj|BAA29775.1| (AP000003) 398aa long hypothetical ferredoxin oxidoreductase alpha-2 subunit [Pyrococcus horikoshii] Length = 398 Score = 755 bits (1928), Expect = 0.0 Identities = 375/395 (94%), Positives = 388/395 (97%) Query: 1 MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEH 60 MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEH Sbjct: 4 MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEH 63 Query: 61 SAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWND 120 SAISA+VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNR+LSAPINIWND Sbjct: 64 SAISAVVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRSLSAPINIWND 123 Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 WQD+ISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE Sbjct: 124 WQDSISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 183 Query: 181 IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAF 240 IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEA+YLVW+AME ARKVIDEAF Sbjct: 184 IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEAKYLVWDAMEKARKVIDEAF 243 Query: 241 AEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300 AEFEK+FGRKYQKIEEY+TDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP Sbjct: 244 AEFEKRFGRKYQKIEEYKTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 303 Query: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV 360 FPVEEIR LAKK KVL FIEKDIS+GLYGAVF DASAAL+NESE+PLMLDFIAGLGGRDV Sbjct: 304 FPVEEIRALAKKAKVLGFIEKDISIGLYGAVFIDASAALVNESERPLMLDFIAGLGGRDV 363 Query: 361 TFNQLDEALSIAKEALEKGKVEKPIHWIGLRKELL 395 TF QLD+AL IA+EALEKG+VEKPIHWIGLRKELL Sbjct: 364 TFGQLDDALRIAEEALEKGEVEKPIHWIGLRKELL 398 >sp|O73986|PORA_PYRHO PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) Length = 395 Score = 755 bits (1928), Expect = 0.0 Identities = 375/395 (94%), Positives = 388/395 (97%) Query: 1 MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEH 60 MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEH Sbjct: 1 MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEH 60 Query: 61 SAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWND 120 SAISA+VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNR+LSAPINIWND Sbjct: 61 SAISAVVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRSLSAPINIWND 120 Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 WQD+ISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE Sbjct: 121 WQDSISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 Query: 181 IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAF 240 IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEA+YLVW+AME ARKVIDEAF Sbjct: 181 IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEAKYLVWDAMEKARKVIDEAF 240 Query: 241 AEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300 AEFEK+FGRKYQKIEEY+TDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP Sbjct: 241 AEFEKRFGRKYQKIEEYKTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300 Query: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV 360 FPVEEIR LAKK KVL FIEKDIS+GLYGAVF DASAAL+NESE+PLMLDFIAGLGGRDV Sbjct: 301 FPVEEIRALAKKAKVLGFIEKDISIGLYGAVFIDASAALVNESERPLMLDFIAGLGGRDV 360 Query: 361 TFNQLDEALSIAKEALEKGKVEKPIHWIGLRKELL 395 TF QLD+AL IA+EALEKG+VEKPIHWIGLRKELL Sbjct: 361 TFGQLDDALRIAEEALEKGEVEKPIHWIGLRKELL 395 >sp|Q51804|PORA_PYRFU PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|11280155|pir||T45088 pyruvate synthase (EC 1.2.7.1) alpha-2 chain [imported] - Pyrococcus furiosus >gi|1197363|emb|CAA59505.1| (X85250) pyruvate ferredoxin oxidoreductase alpha-2 [Pyrococcus furiosus] Length = 396 Score = 727 bits (1857), Expect = 0.0 Identities = 357/395 (90%), Positives = 383/395 (96%) Query: 1 MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEH 60 MPIR VMKANEAAAWAAKLAKPKVIAAFPITPSTL+PEKISEFVANGELDAEFIKVESEH Sbjct: 1 MPIRKVMKANEAAAWAAKLAKPKVIAAFPITPSTLIPEKISEFVANGELDAEFIKVESEH 60 Query: 61 SAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWND 120 SAISA VGA+AAGVRTFTATASQGLALMHE+LFIAAGMRLPIVMAIGNRALSAPINIWND Sbjct: 61 SAISACVGAAAAGVRTFTATASQGLALMHEILFIAAGMRLPIVMAIGNRALSAPINIWND 120 Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 WQDTISQRDTGW+QFYAENNQEALDLIL+AYKVAEDERVLLPAMVGFDAFILTHTVEPVE Sbjct: 121 WQDTISQRDTGWMQFYAENNQEALDLILIAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 Query: 181 IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAF 240 IPDQEVVDEFLGEYEPKHAY+DP RPITQG+LAFPAHYME+RY VWEAME A+KVIDEAF Sbjct: 181 IPDQEVVDEFLGEYEPKHAYIDPARPITQGSLAFPAHYMESRYTVWEAMERAKKVIDEAF 240 Query: 241 AEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300 AEFEKKFGRKYQKIEEY+T+DA+IIFVTMGSLAGTL +W+DKKREEGYKVGAAK+TVYRP Sbjct: 241 AEFEKKFGRKYQKIEEYKTEDADIIFVTMGSLAGTLNEWIDKKREEGYKVGAAKITVYRP 300 Query: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV 360 FPVEEIRELAKK KVLAF+EK+I++GLYGAVFTDASAALINESEKPLM+DFI G GGRDV Sbjct: 301 FPVEEIRELAKKAKVLAFLEKNITIGLYGAVFTDASAALINESEKPLMVDFIVGHGGRDV 360 Query: 361 TFNQLDEALSIAKEALEKGKVEKPIHWIGLRKELL 395 TFNQLDEAL IA++AL++GKVE PI+WIGLR EL+ Sbjct: 361 TFNQLDEALEIAEKALKEGKVENPINWIGLRWELV 395 >gb|AAF91264.1|AF230199_6 (AF230199) pyruvate oxidoreductase alpha subunit [Methanococcus maripaludis] Length = 387 Score = 430 bits (1093), Expect = e-119 Identities = 223/393 (56%), Positives = 286/393 (72%), Gaps = 16/393 (4%) Query: 6 VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65 V+ AAA AAKLA VIAA+PITP T EK+++FVANGEL+AE+IKVESEHSA+SA Sbjct: 6 VITGTSAAAEAAKLADVDVIAAYPITPQTTCVEKLADFVANGELNAEYIKVESEHSAMSA 65 Query: 66 LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125 +GASAAG R FTAT+SQGLALMHEVLF AAGMR+P+VM NRALSAPINIWND QD++ Sbjct: 66 SIGASAAGARAFTATSSQGLALMHEVLFAAAGMRVPVVMMNANRALSAPINIWNDQQDSL 125 Query: 126 SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQE 185 SQRDTGWIQ YAE+NQE LDL++ A+K+AEDE+VLLP MV D FILTHTVEPV +P QE Sbjct: 126 SQRDTGWIQLYAEDNQEVLDLVIQAFKIAEDEKVLLPVMVNLDGFILTHTVEPVTLPKQE 185 Query: 186 VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEK 245 V +F+G YEPKHAYLDPK+P+TQG L P +YME RY + AMENA+KVI + F + Sbjct: 186 NVLDFIGTYEPKHAYLDPKKPMTQGALGDPNYYMETRYAIETAMENAKKVIADVHDAFAE 245 Query: 246 KFGRKYQK--IEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPV 303 KF R Y IE Y + AE + V MGS+ GT+KD +D K++EG ++G K+ YRP P+ Sbjct: 246 KFNRAYGNGLIESYNLEKAENVIVAMGSICGTIKDMIDLKKKEGVEIGLLKIRCYRPLPI 305 Query: 304 EEIRELAKKTKVLAFIEKDISMGL-YGAVFTDASAALINESEKPLMLDFIAGLGGRDVTF 362 E I++ K K +A ++K IS+G+ GA++ D ++ L ++ +++I GLGGRD+T Sbjct: 306 EMIKDALKNAKNVAILDKSISLGMNKGAIYADVASHLKDKK----TVNYIVGLGGRDIT- 360 Query: 363 NQLDEALSIAK--EALEKGKVEKPIHWIGLRKE 393 ++ L I E E GK +WIGL++E Sbjct: 361 --PEDILGIYDDVEISEDGKT----NWIGLKEE 387 >sp|P56810|PORA_METTH PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|7449945|pir||E69099 pyruvate synthase (EC 1.2.7.1) alpha chain - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622870|gb|AAB86209.1| (AE000929) pyruvate oxidoreductase, alpha subunit [Methanobacterium thermoautotrophicum] Length = 383 Score = 414 bits (1052), Expect = e-114 Identities = 209/388 (53%), Positives = 284/388 (72%), Gaps = 11/388 (2%) Query: 6 VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65 V+ AN+A A AAKLAKPKVI +PITP T + E +++FVA+GEL AE+I+VESEHSA+SA Sbjct: 5 VISANQAVAEAAKLAKPKVIPVYPITPQTSISEYLAKFVADGELKAEYIRVESEHSAMSA 64 Query: 66 LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125 VGAS AGVR FTAT+SQGLALMHE+++ AAG+R PIVMA NRALSAP++IWND QD+I Sbjct: 65 CVGASGAGVRVFTATSSQGLALMHEIVYAAAGLRNPIVMANANRALSAPLSIWNDQQDSI 124 Query: 126 SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQE 185 ++RD+GW+Q Y E+ QEALD +LL+Y+V+ED VLLP+MV D FILTHTVEPV+IP QE Sbjct: 125 AERDSGWMQIYVESGQEALDSVLLSYRVSEDRDVLLPSMVCLDGFILTHTVEPVDIPSQE 184 Query: 186 VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEK 245 VD FL E++P+ LDP P++ GT P +YMEARY V +AME +RK+I+ A EF + Sbjct: 185 DVDSFLPEFQPQ-VMLDPDEPMSLGTFTDPDYYMEARYEVEKAMERSRKIIERACREFSE 243 Query: 246 KFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVEE 305 FGR+Y +EEYR +DAEII V MGS+ TL++ +D+ R++G VG K+ V+RPFP EE Sbjct: 244 MFGREYGLVEEYRCEDAEIILVAMGSVCSTLREVIDELRDKGKAVGLLKVRVHRPFPAEE 303 Query: 306 IRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDVTFNQL 365 I+ + +A ++K+I+ + GA++T+ SA L + + FI GLGGRD+T + Sbjct: 304 IKSAVRNASKVAVLDKNITFSVGGALYTEISALLRDRE----VYGFIVGLGGRDITPAHI 359 Query: 366 DEALSIAKEALEKGKVEKPIHWIGLRKE 393 +E + + E+ + WIGL++E Sbjct: 360 EEIVRRTENP------ERSVTWIGLKEE 381 >sp|Q57715|PORA_METJA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|2127892|pir||D64333 pyruvate synthase (EC 1.2.7.1) alpha chain - Methanococcus jannaschii >gi|1590995|gb|AAB98254.1| (U67482) pyruvate ferredoxin oxidoreductase, subunit alpha (porA) [Methanococcus jannaschii] Length = 389 Score = 411 bits (1045), Expect = e-114 Identities = 214/390 (54%), Positives = 279/390 (70%), Gaps = 12/390 (3%) Query: 6 VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65 V+ AAA AAKLA VIAA+PITP T EK++EFVANGELDAE+IKVESEHSA+SA Sbjct: 9 VITGTSAAAEAAKLADVDVIAAYPITPQTTCVEKLAEFVANGELDAEYIKVESEHSAMSA 68 Query: 66 LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125 +GA+A G RTFTATASQGLALMHE+LFIA+GMRLPIVM + NRALSAPINIWND QD+I Sbjct: 69 CIGAAATGARTFTATASQGLALMHEMLFIASGMRLPIVMMVANRALSAPINIWNDHQDSI 128 Query: 126 SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQE 185 ++RD+GWIQ Y E+NQE LD I+ AYK+AE+E VLLP MV D FILTHTVEPV IP E Sbjct: 129 AERDSGWIQIYVEDNQETLDSIIQAYKIAENEDVLLPVMVCLDGFILTHTVEPVTIPKAE 188 Query: 186 VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEK 245 V EFLG YEPKHAYLDP RPITQG + P YME R + EAME A+KVI + EF + Sbjct: 189 RVREFLGVYEPKHAYLDPDRPITQGPVGVPDCYMETRKQIEEAMERAKKVIRDVNEEFAE 248 Query: 246 KFGRKYQK--IEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPV 303 F RKY +E Y D+A+ + V MGS+ GT+K +D+ ++EG VG ++ +RPFP Sbjct: 249 WFKRKYGNGLVEAYNLDNADTVLVAMGSVCGTIKYVIDELKKEGKNVGLLRIRAFRPFPK 308 Query: 304 EEIRELAKKTKVLAFIEKDISMGL-YGAVFTDASAALINESEKPLMLDFIAGLGGRDVTF 362 E+++EL K +A ++K+IS+G GA+ + ++ L N+ + ++I GLGGRD+ Sbjct: 309 EDVKELLKDANNIAVLDKNISLGFNKGALGIEMASILKNKK----VCNYIVGLGGRDIKI 364 Query: 363 NQLDEALSIAKEALEKGKVEKPIHWIGLRK 392 + + ++ ++A + + W+GL++ Sbjct: 365 DDIKTIINHVEKAEDDSTL-----WVGLKE 389 >sp|Q51801|VORA_PYRFU KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (VOR) (2-OXOISOVALERATE OXIDOREDUCTASE ALPHA CHAIN) (2-OXOISOVALERATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|11280154|pir||T45085 2-oxoisovalerate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain vorA - Pyrococcus furiosus >gi|1197360|emb|CAA59502.1| (X85250) 2-ketovalerate ferredoxin oxidoreductase alpha-2 [Pyrococcus furiosus] Length = 394 Score = 392 bits (997), Expect = e-108 Identities = 206/392 (52%), Positives = 275/392 (69%), Gaps = 3/392 (0%) Query: 2 PIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHS 61 PIR V+ N AAA+AA A+ +V+AA+PITP T + EKI+EF+ANGE D ++I VESEHS Sbjct: 5 PIRKVVSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHS 64 Query: 62 AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDW 121 A++A +GASA G RTFTAT++QGLALMHE+L AAG RLPIVM NRA++ P ++W+D Sbjct: 65 AMAACIGASATGARTFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQ 124 Query: 122 QDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEI 181 D++SQRDTGW+QFYAENNQE D +L+AYKVA E V +PAMV AFIL+HT + VE+ Sbjct: 125 TDSLSQRDTGWMQFYAENNQEVYDGVLMAYKVA--ETVNVPAMVVESAFILSHTYDVVEM 182 Query: 182 PDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFA 241 QE+VDEFL +P ++ + PI G LA P Y E RY + +A E A+KVI E Sbjct: 183 IPQELVDEFLPPRKPLYSLANFDEPIAVGALATPNDYYEFRYKLAKAHEEAKKVIKEVGK 242 Query: 242 EFEKKFGRKY-QKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300 EF ++FGR Y Q IE DDA+ +F+ MGSL GT+K+ VD R+EGYKVG AK+ +RP Sbjct: 243 EFGERFGRDYSQMIETGYIDDADFVFMGMGSLMGTVKEAVDLLRKEGYKVGYAKVRWFRP 302 Query: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV 360 FP EE+ E+A+ K +A ++++ S G G +FT++ AL N S PLM ++I GLGGRDV Sbjct: 303 FPKEELVEIAESVKGIAVLDRNFSFGQEGILFTESKGALYNSSAHPLMKNYIVGLGGRDV 362 Query: 361 TFNQLDEALSIAKEALEKGKVEKPIHWIGLRK 392 T + K+ +E GKV+K + W L++ Sbjct: 363 TVKDIKAIADDMKKVIESGKVDKEVVWYHLKR 394 >pir||A71114 probable ferredoxin oxidoreductase alpha subunit - Pyrococcus horikoshii >gi|3257088|dbj|BAA29771.1| (AP000003) 397aa long hypothetical ferredoxin oxidoreductase alpha subunit [Pyrococcus horikoshii] Length = 397 Score = 388 bits (986), Expect = e-107 Identities = 201/392 (51%), Positives = 271/392 (68%), Gaps = 3/392 (0%) Query: 2 PIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHS 61 PI+ V+ N AAA+AA A+ +V+AA+PITP T + EKI+EF+ANGE D ++I VESEHS Sbjct: 8 PIKKVVSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHS 67 Query: 62 AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDW 121 A++A +GASA G R FTAT++QGLALMHE+L AAG RLPIVM NRA++ P ++W+D Sbjct: 68 AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGSRLPIVMVNVNRAMAPPWSVWDDQ 127 Query: 122 QDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEI 181 D++SQRDTGW+QFYAENNQE D +L+AYKVA E V +P M+ AFIL+HT E V + Sbjct: 128 TDSLSQRDTGWMQFYAENNQEVYDGVLMAYKVA--ETVNIPTMIIESAFILSHTYEVVNM 185 Query: 182 PDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFA 241 QE+VDEFL +P + D + PI G LA PA Y E RY + +A E A+KVI Sbjct: 186 IPQELVDEFLPPRKPLYTLTDFENPIAVGALATPADYYEFRYKIAKAHEEAKKVIKSVGK 245 Query: 242 EFEKKFGRKYQK-IEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300 EF ++FGR Y K IE +DA+ +F+ MGSL GT+K+ VD R+EGYKVG AK+ +RP Sbjct: 246 EFGERFGRDYSKMIETGYIEDADFVFMGMGSLMGTVKEAVDLLRKEGYKVGYAKVRWFRP 305 Query: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV 360 FP EE+ E+A+ K +A ++++ S G G +FT+A AL N +P+M D+I GLGGRD Sbjct: 306 FPKEELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNTGVRPIMKDYIVGLGGRDF 365 Query: 361 TFNQLDEALSIAKEALEKGKVEKPIHWIGLRK 392 T + K+ +E GK++K I W L++ Sbjct: 366 TVRDVKAIAEDMKKVVESGKLDKEIEWYHLKR 397 >sp|O58413|VORA_PYRHO KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (VOR) (2-OXOISOVALERATE OXIDOREDUCTASE ALPHA CHAIN) (2-OXOISOVALERATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) Length = 394 Score = 388 bits (986), Expect = e-107 Identities = 201/392 (51%), Positives = 271/392 (68%), Gaps = 3/392 (0%) Query: 2 PIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHS 61 PI+ V+ N AAA+AA A+ +V+AA+PITP T + EKI+EF+ANGE D ++I VESEHS Sbjct: 5 PIKKVVSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHS 64 Query: 62 AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDW 121 A++A +GASA G R FTAT++QGLALMHE+L AAG RLPIVM NRA++ P ++W+D Sbjct: 65 AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGSRLPIVMVNVNRAMAPPWSVWDDQ 124 Query: 122 QDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEI 181 D++SQRDTGW+QFYAENNQE D +L+AYKVA E V +P M+ AFIL+HT E V + Sbjct: 125 TDSLSQRDTGWMQFYAENNQEVYDGVLMAYKVA--ETVNIPTMIIESAFILSHTYEVVNM 182 Query: 182 PDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFA 241 QE+VDEFL +P + D + PI G LA PA Y E RY + +A E A+KVI Sbjct: 183 IPQELVDEFLPPRKPLYTLTDFENPIAVGALATPADYYEFRYKIAKAHEEAKKVIKSVGK 242 Query: 242 EFEKKFGRKYQK-IEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300 EF ++FGR Y K IE +DA+ +F+ MGSL GT+K+ VD R+EGYKVG AK+ +RP Sbjct: 243 EFGERFGRDYSKMIETGYIEDADFVFMGMGSLMGTVKEAVDLLRKEGYKVGYAKVRWFRP 302 Query: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV 360 FP EE+ E+A+ K +A ++++ S G G +FT+A AL N +P+M D+I GLGGRD Sbjct: 303 FPKEELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNTGVRPIMKDYIVGLGGRDF 362 Query: 361 TFNQLDEALSIAKEALEKGKVEKPIHWIGLRK 392 T + K+ +E GK++K I W L++ Sbjct: 363 TVRDVKAIAEDMKKVVESGKLDKEIEWYHLKR 394 >pir||B75047 probable 2-oxoisovalerate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain PAB1472 [similarity] - Pyrococcus abyssi (strain Orsay) >gi|5458784|emb|CAB50271.1| (AJ248287) KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (EC 1.-.-.-) (VOR) [Pyrococcus abyssi] Length = 395 Score = 383 bits (972), Expect = e-105 Identities = 196/392 (50%), Positives = 274/392 (69%), Gaps = 3/392 (0%) Query: 2 PIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHS 61 PI+ V+ N AAA+A A+ +V+AA+PITP T + EKI+EF+ANGE D ++I VESEHS Sbjct: 6 PIKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHS 65 Query: 62 AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDW 121 A++A +GASA G R FTAT++QGLALMHE+L AAG RLPIVM NRA++ P ++W+D Sbjct: 66 AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQ 125 Query: 122 QDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEI 181 D++SQRDTGW+QFYAENNQE D +L+A+KVA E V +PAMV AFIL+HT E V + Sbjct: 126 TDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVA--ETVNVPAMVVESAFILSHTYEIVNM 183 Query: 182 PDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFA 241 QE+VDEFL +P ++ D + PI G LA PA Y E RY + A E A+KVI + Sbjct: 184 IPQELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGR 243 Query: 242 EFEKKFGRKY-QKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300 EF ++FGR Y + IE+ DDA+ +F+ MGSL GT+K+ V+ R++GYKVG AK+ +RP Sbjct: 244 EFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWFRP 303 Query: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV 360 FP EE+ E+A+ K +A ++++ S G G +FT+A AL N +P+M ++I GLGGRD Sbjct: 304 FPREELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIMKNYIVGLGGRDF 363 Query: 361 TFNQLDEALSIAKEALEKGKVEKPIHWIGLRK 392 T + + K+ +E GK+++ + W L++ Sbjct: 364 TVSDVKAIAEDMKKVIESGKLDREVEWYHLKR 395 >emb|CAA59457.1| (X85171) alpha subunit of pyruvate ferredoxin oxidoreductase [Thermotoga maritima] >gi|4980501|gb|AAD35111.1|AE001690_5 (AE001690) pyruvate ferredoxin oxidoreductase, alpha subunit [Thermotoga maritima] Length = 394 Score = 340 bits (863), Expect = 2e-92 Identities = 176/389 (45%), Positives = 251/389 (64%), Gaps = 3/389 (0%) Query: 4 RTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAI 63 R + EA A A + +P V+AA+PITP T + E + FVA+G + E I VESEHSA+ Sbjct: 9 RVAVTGAEAVANAMRQIEPDVVAAYPITPQTPIVEYFARFVADGVVRTEMIPVESEHSAM 68 Query: 64 SALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQD 123 SA+VGA+AAG R TAT++ GLALMHE+++IAA RLPIVM + NRALS PINI D D Sbjct: 69 SAVVGAAAAGARAMTATSANGLALMHEIVYIAASYRLPIVMPVVNRALSGPINIHCDHSD 128 Query: 124 TISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPD 183 +++RD+GWIQ +AE NQEA D +LA ++AE E V LP MV D FIL+H VEPVE Sbjct: 129 AMAERDSGWIQLFAETNQEAYDFTILAVRLAEHEDVRLPVMVNLDGFILSHGVEPVEFYP 188 Query: 184 QEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEF 243 E+V +F+GE +P + LD + P+T G L +Y E + EAMEN +KV E EF Sbjct: 189 DELVKKFVGELKPMYPLLDTEHPVTWGPLDLYDYYFEHKRQQIEAMENVKKVFPEIAKEF 248 Query: 244 EKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPV 303 E+ FGRKY +E YR +DAE + V +GS T+K VD+ REEGYKVG+ K+ ++RPFP Sbjct: 249 EETFGRKYWFVEPYRMEDAEHVMVALGSTNSTIKYVVDELREEGYKVGSLKIWMFRPFPK 308 Query: 304 EEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDVTFN 363 E+++EL K + +++ +S G ++ +AL + +P++ ++ GLGGRD+ Sbjct: 309 EQLQELLNGRKSVVVLDRAVSFGAEAPLYEAVKSALYEVAARPMLGSYVYGLGGRDIKPE 368 Query: 364 QLDEALSIAKEALEKGKVEKPIHWIGLRK 392 + +A ++A+ + ++GLR+ Sbjct: 369 HIRKAF---EDAINGNLIADEQRYLGLRE 394 >sp|O05651|PORA_THEMA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|7449946|pir||C72427 pyruvate synthase (EC 1.2.7.1) alpha chain - Thermotoga maritima (strain MSB8) Length = 392 Score = 340 bits (863), Expect = 2e-92 Identities = 176/389 (45%), Positives = 251/389 (64%), Gaps = 3/389 (0%) Query: 4 RTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAI 63 R + EA A A + +P V+AA+PITP T + E + FVA+G + E I VESEHSA+ Sbjct: 7 RVAVTGAEAVANAMRQIEPDVVAAYPITPQTPIVEYFARFVADGVVRTEMIPVESEHSAM 66 Query: 64 SALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQD 123 SA+VGA+AAG R TAT++ GLALMHE+++IAA RLPIVM + NRALS PINI D D Sbjct: 67 SAVVGAAAAGARAMTATSANGLALMHEIVYIAASYRLPIVMPVVNRALSGPINIHCDHSD 126 Query: 124 TISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPD 183 +++RD+GWIQ +AE NQEA D +LA ++AE E V LP MV D FIL+H VEPVE Sbjct: 127 AMAERDSGWIQLFAETNQEAYDFTILAVRLAEHEDVRLPVMVNLDGFILSHGVEPVEFYP 186 Query: 184 QEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEF 243 E+V +F+GE +P + LD + P+T G L +Y E + EAMEN +KV E EF Sbjct: 187 DELVKKFVGELKPMYPLLDTEHPVTWGPLDLYDYYFEHKRQQIEAMENVKKVFPEIAKEF 246 Query: 244 EKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPV 303 E+ FGRKY +E YR +DAE + V +GS T+K VD+ REEGYKVG+ K+ ++RPFP Sbjct: 247 EETFGRKYWFVEPYRMEDAEHVMVALGSTNSTIKYVVDELREEGYKVGSLKIWMFRPFPK 306 Query: 304 EEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDVTFN 363 E+++EL K + +++ +S G ++ +AL + +P++ ++ GLGGRD+ Sbjct: 307 EQLQELLNGRKSVVVLDRAVSFGAEAPLYEAVKSALYEVAARPMLGSYVYGLGGRDIKPE 366 Query: 364 QLDEALSIAKEALEKGKVEKPIHWIGLRK 392 + +A ++A+ + ++GLR+ Sbjct: 367 HIRKAF---EDAINGNLIADEQRYLGLRE 392 >emb|CAC11767.1| (AL445064) probable 2-ketovalerate ferredoxin oxidoreductase alpha-2 chain [Thermoplasma acidophilum] Length = 402 Score = 326 bits (827), Expect = 3e-88 Identities = 171/391 (43%), Positives = 254/391 (64%), Gaps = 10/391 (2%) Query: 4 RTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAI 63 RT+M N+A A+ AKLA+ K I+A+PITP T + EK++ +AN ELDA++++VESEHSA+ Sbjct: 18 RTIMTGNDAVAYGAKLARVKFISAYPITPQTTIVEKLASMIANDELDAKYVEVESEHSAL 77 Query: 64 SALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQD 123 +A+ + GVR++TAT+S GL MHE+L AG RLPIVM++ NRA+ P NIW D D Sbjct: 78 AAVFASELTGVRSYTATSSHGLLYMHEMLHWVAGQRLPIVMSVVNRAIGPPWNIWADQSD 137 Query: 124 TISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPD 183 TI+QRDTGW+Q Y+E+NQEA+D I++ YK+AE+ V+LP M DAFIL+HT EPV + D Sbjct: 138 TINQRDTGWMQVYSESNQEAMDTIIMGYKIAENSGVMLPLMSMEDAFILSHTSEPVTMRD 197 Query: 184 QEVVDEFLGEYEPKHAYLDPKRPITQGTLAFP-AHYMEARYLVWEAMENARKVIDEAFAE 242 Q++V+E+L + + K +DP+ P+ G+ P +ME + + ++M NARKVI E + Sbjct: 198 QDLVNEYLPDLDLKFR-IDPENPMGYGSYDTPDGSFMEFKKDMIDSMNNARKVIKEETQK 256 Query: 243 FEKKFGRKY-QKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPF 301 F + F Y IE YR DDA+ + MG++A T + +D+ RE G +G ++ +RPF Sbjct: 257 FNEMFETNYGALIERYRMDDADYAIIAMGTVASTARFVIDRLRENGLNIGLIRIRYFRPF 316 Query: 302 PVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDVT 361 P +EI E K K I++ +S GL G +++ + L P+ FI G+GGRDV Sbjct: 317 PYDEILEDLKNVKSAGVIDRSVSFGLAGVTYSEVISGLYGRINIPVS-SFIVGIGGRDV- 374 Query: 362 FNQLDEALSIAKEALEKGKVEKPIHWIGLRK 392 ++++ SIA E + G HWI +++ Sbjct: 375 --RIEDIESIA-ETIRNGST--GTHWINVKR 400 >gi|11499291 pyruvate ferredoxin oxidoreductase, subunit alpha (porA) [Archaeoglobus fulgidus] >gi|7449947|pir||D69462 pyruvate synthase (EC 1.2.7.1) alpha chain - Archaeoglobus fulgidus >gi|2648853|gb|AAB89548.1| (AE000986) pyruvate ferredoxin oxidoreductase, subunit alpha (porA) [Archaeoglobus fulgidus] Length = 391 Score = 322 bits (816), Expect = 5e-87 Identities = 178/377 (47%), Positives = 239/377 (63%), Gaps = 3/377 (0%) Query: 3 IRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGEL-DAEFIKVESEHS 61 +R V++ + A++ KL KP VI A+PITP T + E ++ ANGEL DAE+I ESE Sbjct: 1 MRKVVRGFYSVAYSVKLCKPNVICAYPITPQTEIVENLAAMYANGELGDAEYITAESEFG 60 Query: 62 AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDW 121 A S LVGASAAG R FTAT SQGL LM EVLF AAGMRLPIV+ NRALSAP++IWND Sbjct: 61 AASMLVGASAAGARVFTATCSQGLILMSEVLFNAAGMRLPIVLVNTNRALSAPLSIWNDH 120 Query: 122 QDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEI 181 QD+++ RD G +Q Y ENNQEA D+I AYKVAE+ +VLLP M+ D + LTH EPV++ Sbjct: 121 QDSMAMRDAGIMQVYVENNQEAHDMIPQAYKVAENRKVLLPFMICMDGYKLTHAYEPVDL 180 Query: 182 PDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFA 241 +QE VD FL YEP AY+ K+P+ G A P YME R + +AME ARK++ + F Sbjct: 181 LEQETVDSFLPPYEPA-AYMTTKKPLAFGCYAPPHVYMEFRVAMQQAMERARKIMLDVFK 239 Query: 242 EFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPF 301 E+ + GR + D++I V MGS+ G L+ V++ R EG VG K+ +RPF Sbjct: 240 EWGELTGRDWGGHITVDFPDSKIFVVAMGSVVGLLRKVVEELRGEGLSVGLIKIRTFRPF 299 Query: 302 PVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDVT 361 PVEE+RE K + + +++ +S G G V + +A+ S + F GLGGRD+ Sbjct: 300 PVEELREALKDAEKVIVLDRSVSFGYEGPVSIELKSAIYGHSSAEI-YSFAVGLGGRDMP 358 Query: 362 FNQLDEALSIAKEALEK 378 + L++ + E EK Sbjct: 359 KDFLEKIIRDVAEGREK 375 >gb|AAK41454.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase alpha chain) (porA-1) [Sulfolobus solfataricus] Length = 385 Score = 308 bits (781), Expect = 6e-83 Identities = 160/352 (45%), Positives = 232/352 (65%), Gaps = 5/352 (1%) Query: 10 NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISALVGA 69 N A A+A K AKPKV+A FPITP T + EK+SE++++ EL AE IKVESEHSA++++ GA Sbjct: 14 NHAVAYAVKQAKPKVLAVFPITPQTTMLEKLSEYISSEELKAELIKVESEHSALASIYGA 73 Query: 70 SAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTISQRD 129 + AG R FTAT+SQGL M E+++ A G R+PIV A+ RA++ P +IW+D QD +S+RD Sbjct: 74 ALAGARVFTATSSQGLLYMTEMIYWAGGQRVPIVAAVATRAIAEPWSIWDDHQDFVSKRD 133 Query: 130 TGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEVVDE 189 WIQ AEN QEA D+ + A++++EDERV+LP M+GFD FILTHT+E +E+ + VD Sbjct: 134 AIWIQIMAENVQEAYDMTIQAFRISEDERVILPVMMGFDGFILTHTMERIEVLEDNEVDN 193 Query: 190 FLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEKKFGR 249 FL + +D PI G +A P Y++ RY +AME A+ VI+E E+E+ GR Sbjct: 194 FLPPRQ--FNLIDFSDPIAIGPIATPEEYIKYRYEAMKAMERAKGVIEEIMGEYERISGR 251 Query: 250 K-YQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVEEIRE 308 K + +E Y+ +DA+ +FVTMG+ +G K VD+ R+ G K G K+ V+RPFP E++ E Sbjct: 252 KQHGLVECYKCEDAKYVFVTMGAWSGDGKAAVDRLRDSGVKTGLLKIRVFRPFPKEKVEE 311 Query: 309 LAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV 360 + K + ++ S G G + + AAL + + +AG+GG+DV Sbjct: 312 YLRSMKGVVVFDRAYSYGYGGILVNEIKAALY--GYRVPVYSVVAGIGGKDV 361 >gb|AAK42867.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase alpha chain) (porA-2) [Sulfolobus solfataricus] Length = 400 Score = 282 bits (714), Expect = 5e-75 Identities = 154/367 (41%), Positives = 220/367 (58%), Gaps = 7/367 (1%) Query: 3 IRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSA 62 IR ++ NEA A KLA+ V +PITP T + EK++E A GE++ E ++VESEHSA Sbjct: 2 IRKIISGNEAVALGVKLARVGVTGIYPITPQTTIIEKLAEMRAKGEIETEIVRVESEHSA 61 Query: 63 ISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQ 122 ++A GA+ GVR FTATASQGL MHE+++ AG R+P+VM +G RA+ AP NIWN+ Sbjct: 62 MAATFGAALGGVRAFTATASQGLLYMHEMVWWVAGSRVPVVMVVGTRAVGAPWNIWNEHT 121 Query: 123 DTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIP 182 D S+RD+GWI +A N QEALDL L A++++EDERV LP M+G D FIL+HT V IP Sbjct: 122 DFTSERDSGWIMAFASNPQEALDLTLQAFRISEDERVFLPMMIGMDGFILSHTKTNVLIP 181 Query: 183 DQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAE 242 DQ+ VD+FL + +DP+ P+ G + P YM R + A+ N+ VI E E Sbjct: 182 DQDQVDDFLPPRRQPYV-IDPEDPVGMGNIFPPEGYMRLRESIDLALRNSEDVIKEIGRE 240 Query: 243 FEKKFG--RKYQKIE-EYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYR 299 + KK Y + Y+ +DA+ V MG+ AG + VD RE+G K+G ++ R Sbjct: 241 YNKKINPLGDYSTLNVSYKLEDADYAVVLMGAWAGDAMEAVDTLREKGIKIGMLRIRYLR 300 Query: 300 PFPVEEIRELAKKTKVLAFIEKDISMGLYGA-VFTDASAALINESEKPLMLDFIAGLGGR 358 P+ +EIR K K + +++ S G G ++ + + + N P + ++GLGG Sbjct: 301 PWSEKEIRNTLKDKKAVLVLDRSTSFGRGGGPLYVEIKSTISN--VVPQIKGVVSGLGGV 358 Query: 359 DVTFNQL 365 V N L Sbjct: 359 TVNKNDL 365 >pir||H71857 pyruvate ferrodoxin oxidoreductase - Helicobacter pylori (strain J99) >gi|4155626|gb|AAD06616.1| (AE001531) Pyruvate ferrodoxin oxidoreductase [Helicobacter pylori J99] Length = 407 Score = 277 bits (700), Expect = 2e-73 Identities = 156/389 (40%), Positives = 232/389 (59%), Gaps = 3/389 (0%) Query: 6 VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65 V N A++ A + A+ VIAA+PITPST + + F NG +D EF+ VESEH+A+SA Sbjct: 12 VWDGNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYVDGEFVLVESEHAAMSA 71 Query: 66 LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125 VGA+AAG R TAT+SQGLALM EVL+ A+GMRLPIV+ + NRAL+AP+NI D D Sbjct: 72 CVGAAAAGGRVSTATSSQGLALMVEVLYQASGMRLPIVLNLVNRALAAPLNIHGDHSDMY 131 Query: 126 SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQE 185 RD+GWI N QEA D L+A+++AE ++V +P +V D F+ +HTV+ V Sbjct: 132 LSRDSGWISLCTCNPQEAYDFTLMAFRIAEHQKVRVPTIVNQDGFLCSHTVQNVRPLSDA 191 Query: 186 VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEK 245 V +F+GEY+ KH+ LD +P++ G A + E + + A+ +A VI+E F +F K Sbjct: 192 VAYQFVGEYQTKHSLLDFDKPVSYGAQAEEEWHYEHKAQLHHAIMSASSVIEEVFNDFAK 251 Query: 246 KFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVEE 305 GR+Y + ++ +DAEI +G+ + + R++G K G A + RPFP E Sbjct: 252 LTGRQYHLTKTFQLEDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSLRPFPYER 311 Query: 306 IRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINE--SEKPLMLDFIAGLGGRDVTFN 363 + + K K LA ++K G GA+F + ++A+ ++ P++ ++I GLG RD+T Sbjct: 312 LGQDLKNLKALAILDKSSPAGAMGAMFNEVTSAVYQTQGTKHPVVSNYIYGLGERDMTIV 371 Query: 364 QLDEALSIAKEALEKGKVEKPI-HWIGLR 391 L E E KG + P ++GLR Sbjct: 372 HLCEIFEEINEDALKGTLTHPTQQFVGLR 400 >pir||F64658 pyruvate synthase (EC 1.2.7.1) alpha chain - Helicobacter pylori (strain 26695) >gi|2314261|gb|AAD08154.1| (AE000617) pyruvate ferredoxin oxidoreductase, alpha subunit [Helicobacter pylori 26695] Length = 407 Score = 275 bits (696), Expect = 6e-73 Identities = 155/388 (39%), Positives = 231/388 (58%), Gaps = 3/388 (0%) Query: 6 VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65 V N A++ A + A+ VIAA+PITPST + + F NG +D EF+ VESEH+A+SA Sbjct: 12 VWDGNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYVDGEFVLVESEHAAMSA 71 Query: 66 LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125 VGA+AAG R TAT+SQGLALM EVL+ A+GMRLPIV+ + NRAL+AP+NI D D Sbjct: 72 CVGAAAAGGRVSTATSSQGLALMVEVLYQASGMRLPIVLNLVNRALAAPLNIHGDHSDMY 131 Query: 126 SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQE 185 RD+GWI N QEA D L+A+++AE ++V +P +V D F+ +HTV+ V Sbjct: 132 LSRDSGWISLCTCNPQEAYDFTLMAFRIAEHQKVRVPTIVNQDGFLCSHTVQNVRPLSDA 191 Query: 186 VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEK 245 V +F+GEY+ KH+ LD +P++ G A + E + + A+ +A VI+E F +F K Sbjct: 192 VAYQFVGEYQTKHSLLDFDKPVSYGAQAEEEWHYEHKAQLHHAIMSASSVIEEVFNDFAK 251 Query: 246 KFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVEE 305 GR+Y + ++ +DAEI +G+ + + R++G K G A + RPFP E Sbjct: 252 LTGRQYHLTKTFQLEDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSLRPFPYER 311 Query: 306 IRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINE--SEKPLMLDFIAGLGGRDVTFN 363 + + K K LA ++K G GA+F + ++A+ ++ P++ ++I GLG RD+T Sbjct: 312 LGQDLKNLKALAILDKSSPAGTMGAMFNEVTSAVYQTQGTKHPVVSNYIYGLGERDMTIA 371 Query: 364 QLDEALSIAKEALEKGKVEKPI-HWIGL 390 L E E KG + P ++GL Sbjct: 372 HLCEIFEEINEDALKGTLTHPTQQFVGL 399 >gb|AAC02293.1| (AF013980) pyruvate:ferredoxin oxidoreductase alpha subunit [Helicobacter pylori] Length = 396 Score = 273 bits (691), Expect = 2e-72 Identities = 152/375 (40%), Positives = 228/375 (60%), Gaps = 2/375 (0%) Query: 6 VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65 V N A++ A + A+ VIAA+PITPST + + F NG +D EF+ VESEH+A+SA Sbjct: 12 VWDGNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYIDGEFVLVESEHAAMSA 71 Query: 66 LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125 VGA+AAG R TAT+SQGLALM EVL+ A+GMRLPIV+ + NRAL+AP+NI D D Sbjct: 72 CVGAAAAGGRVSTATSSQGLALMVEVLYQASGMRLPIVLNLVNRALAAPLNIHGDHSDMY 131 Query: 126 SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQE 185 RD+GWI N QEA D L+A+K+AE ++V +P +V D F+ +HTV+ V Sbjct: 132 LSRDSGWISLCTCNPQEAYDFTLMAFKIAEHQKVRVPTIVNQDGFLCSHTVQNVRPLSDA 191 Query: 186 VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEK 245 V +F+GEY+ KH+ LD +P++ G A + E + + A+ +A VI+E F +F K Sbjct: 192 VAYQFVGEYQTKHSLLDFDKPVSYGAQAEEEWHYEHKAQLHHAIMSASSVIEEVFNDFAK 251 Query: 246 KFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVEE 305 GR+Y + ++ +DAEI +G+ + + R++G K G A + RPFP E+ Sbjct: 252 LTGRQYHLTKTFQLEDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSLRPFPYEK 311 Query: 306 IRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINE--SEKPLMLDFIAGLGGRDVTFN 363 + + K K LA ++K G GA+F + ++A+ ++ P++ ++I GLG RD+T Sbjct: 312 LGQDLKNLKALAILDKSSPAGAMGAMFNEVTSAVYQTQGTKHPVVSNYIYGLGERDMTIA 371 Query: 364 QLDEALSIAKEALEK 378 L + L + + L K Sbjct: 372 HLWKFLKKSMKTLLK 386 >gb|AAK42308.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase alpha chain) (porA-like) [Sulfolobus solfataricus] Length = 415 Score = 264 bits (667), Expect = 2e-69 Identities = 145/400 (36%), Positives = 221/400 (55%), Gaps = 15/400 (3%) Query: 6 VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65 +M +A A AA A V+AA+PI P T V + IS+ +A+GELDAEFI E EH Sbjct: 13 LMNGTQAVAHAAMYADVDVVAAYPIRPYTEVMDTISKLIADGELDAEFIVAEGEHGQFET 72 Query: 66 LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125 + AS AG RT ++ G E + + A R P+V IGNRAL P + D + Sbjct: 73 VKHASLAGARTLVGSSGVGWLYAMEAIVVTATDRAPVVAIIGNRALDDPGAYGVEHNDAL 132 Query: 126 SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQE 185 RD GW+ + + QEA D LLAY++AED+RVLLP + D LTH+ + V +P +E Sbjct: 133 MVRDVGWLLVWVDTAQEAFDTALLAYRIAEDQRVLLPLGISMDGGFLTHSEQIVRLPPRE 192 Query: 186 VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEK 245 +V FL Y + P PIT ME R EAME AR VI EA+ EF+K Sbjct: 193 LVKNFLPPYNRGKYLVHPDNPITVAPQVNEDWVMEIRRQHEEAMERARSVIVEAYEEFKK 252 Query: 246 KFGR-----------KYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAK 294 FGR + +E Y DDAE++ + MG+++ +K + R +GYKVG + Sbjct: 253 VFGRYPGSTSDLQMPENPFVEPYMIDDAEVVLIGMGTVSKPMKVAIKNMRRQGYKVGMLR 312 Query: 295 MTVYRPFPVEEIRELAKKTKVLAFIEKDISMG---LYGAVFTDASAALINESEKPLMLDF 351 + +RPFP +++ ++V+ I++D SMG G ++ + ++L + ++P +++F Sbjct: 313 IRWFRPFPTQDVIRYLANSRVVCVIDRDYSMGSPNRGGVIYHEVRSSLYDLDQRPRVMNF 372 Query: 352 IAGLGGRDVTFNQLDEALSIAKEALEKGKVEKPIHWIGLR 391 I GLGGR++T +++ + I E + + KP++W+G+R Sbjct: 373 IGGLGGREITIQDVEKIIKIGYEHRDT-PITKPVYWVGVR 411 >pir||S74041 pyruvate synthase (EC 1.2.7.1) alpha chain - Sulfolobus solfataricus >gi|1707735|emb|CAA69455.1| (Y08256) pyruvate-ferredoxin oxidoreductase alpha-2 [Sulfolobus solfataricus] Length = 415 Score = 264 bits (667), Expect = 2e-69 Identities = 145/400 (36%), Positives = 221/400 (55%), Gaps = 15/400 (3%) Query: 6 VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65 +M +A A AA A V+AA+PI P T V + IS+ +A+GELDAEFI E EH Sbjct: 13 LMNGTQAVAHAAMYADVDVVAAYPIRPYTEVMDTISKLIADGELDAEFIVAEGEHGQFET 72 Query: 66 LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125 + AS AG RT ++ G E + + A R P+V IGNRAL P + D + Sbjct: 73 VKHASLAGARTLVGSSGVGWLYAMEAIVVTATDRAPVVAIIGNRALDDPGAYGVEHNDAL 132 Query: 126 SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQE 185 RD GW+ + + QEA D LLAY++AED+RVLLP + D LTH+ + V +P +E Sbjct: 133 MVRDVGWLLVWVDTAQEAFDTALLAYRIAEDQRVLLPLGISMDGGFLTHSEQIVRLPPRE 192 Query: 186 VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEK 245 +V FL Y + P PIT ME R EAME AR VI EA+ EF+K Sbjct: 193 LVKNFLPPYNRGKYLVHPDNPITVAPQVNEDWVMEIRRQHEEAMERARSVIVEAYEEFKK 252 Query: 246 KFGR-----------KYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAK 294 FGR + +E Y DDAE++ + MG+++ +K + R +GYKVG + Sbjct: 253 VFGRYPGSTSDLQMPENPFVEPYMIDDAEVVLIGMGTVSKPMKVAIKNMRRQGYKVGMLR 312 Query: 295 MTVYRPFPVEEIRELAKKTKVLAFIEKDISMG---LYGAVFTDASAALINESEKPLMLDF 351 + +RPFP +++ ++V+ I++D SMG G ++ + ++L + ++P +++F Sbjct: 313 IRWFRPFPTQDVIRYLANSRVVCVIDRDYSMGSPNRGGVIYHEVRSSLYDLDQRPRVMNF 372 Query: 352 IAGLGGRDVTFNQLDEALSIAKEALEKGKVEKPIHWIGLR 391 I GLGGR++T +++ + I E + + KP++W+G+R Sbjct: 373 IGGLGGREITIQDVEKIIKIGYEHRDT-PITKPVYWVGVR 411 >gi|11499635 2-ketoisovalerate ferredoxin oxidoreductase, subunit alpha (vorA) [Archaeoglobus fulgidus] >gi|7449955|pir||D69506 probable 2-oxoisovalerate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain AF2053 [similarity] - Archaeoglobus fulgidus >gi|2648476|gb|AAB89196.1| (AE000961) 2-ketoisovalerate ferredoxin oxidoreductase, subunit alpha (vorA) [Archaeoglobus fulgidus] Length = 366 Score = 243 bits (613), Expect = 3e-63 Identities = 145/368 (39%), Positives = 215/368 (58%), Gaps = 30/368 (8%) Query: 3 IRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSA 62 ++ ++ +NEA A A KLAKP VIAA+PITP + + EK+SE V +GELD+ F++VESEHSA Sbjct: 13 MKKLLTSNEAIAEAVKLAKPDVIAAYPITPQSPIVEKLSEMVDSGELDSRFVRVESEHSA 72 Query: 63 ISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQ 122 + ++GA+ AG R FTAT+S GLA M+E+ + AAG RLPIVMA+ R++ AP NI D Sbjct: 73 MGVVIGAATAGARVFTATSSHGLAYMYEMCWWAAGSRLPIVMALAARSIGAPWNIHGDHL 132 Query: 123 DTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIP 182 D ++ RD GWI AEN QEA D+ L A+ ++E+ V +P V D F ++HT E VE+ Sbjct: 133 DLMAMRDLGWIISVAENAQEAFDMTLNAFMLSEE--VNIPVAVAIDGFTMSHTAEVVEVR 190 Query: 183 DQEVVDEFLGEYEPKHAY-LDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFA 241 + E+ K AY + P + + F M ARY + + +EN+ ++I Sbjct: 191 EVEIPPR-------KQAYRILPGMDVALNAVTFGEARMTARYDLAKDLENSAELI----- 238 Query: 242 EFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPF 301 EK++G +E YR +DA+ V G L+G +KD VD REEG K+G ++ RPF Sbjct: 239 --EKEYG---GLVERYRLEDADYAVVVTGGLSGDVKDAVDMLREEGVKMGVLRLKFIRPF 293 Query: 302 PVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDVT 361 P + ++ L + V+ D L G + + +A + ++ +AG+GGR T Sbjct: 294 PKKAVKSLPSQVLVVDRANTD----LRGTLSVEVAACGVEN------VNVVAGIGGRYPT 343 Query: 362 FNQLDEAL 369 +L L Sbjct: 344 VEELYSCL 351 >gb|AAC38206.1| (AF021092) PorA subunit of pyruvate:flavodoxin oxidoreductase [Helicobacter pylori] Length = 408 Score = 230 bits (581), Expect = 2e-59 Identities = 139/390 (35%), Positives = 214/390 (54%), Gaps = 4/390 (1%) Query: 6 VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65 V N A++ A + A+ VIAA+PITPST + + F NG +D +F VESEH+A+SA Sbjct: 12 VWDGNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYIDGDFALVESEHAAMSA 71 Query: 66 LVGASAAGVRTFTATASQGLALMHEVLFI-AAGMRLPIVMAIGNRALSAPINIWNDWQDT 124 VGA+AAG R TAT+SQG + +GMR IV + NRAL+AP+NI D D Sbjct: 72 CVGAAAAGGRVSTATSSQGSGVNGRGFITKVSGMRSAIVGNLVNRALAAPLNIHGDHSDM 131 Query: 125 ISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQ 184 RD+GWI N QEA D L+A+K+ E ++V +P +V D F+ +HTV+ V Sbjct: 132 YLSRDSGWISLCTCNPQEAYDFTLMAFKLGEHQKVRVPTIVNQDGFLCSHTVQNVRPLSD 191 Query: 185 EVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFE 244 V +F+GEY+ KH+ +D +P++ G A + E + + A+ +A VI+E F +F Sbjct: 192 GVAYQFVGEYQTKHSLVDFDKPVSYGAQAEEEWHYEHKARLHHAIMSASSVIEEVFNDFA 251 Query: 245 KKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVE 304 K GR+Y + ++ +DAEI +G+ + + R++G K G A + P + Sbjct: 252 KLTGRQYHLTKTFQLEDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSCAPSLMR 311 Query: 305 EIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINE--SEKPLMLDFIAGLGGRDVTF 362 + K K LA ++K G GA+F + ++ + ++ P++ ++I GLG RD+T Sbjct: 312 RLGRDLKNLKALAILDKRSPAGAMGAMFNEVTSTVYQTQGTKHPVVSNYIYGLGERDMTI 371 Query: 363 NQLDEALSIAKEALEKGKVEKPI-HWIGLR 391 L E E KG + P ++GLR Sbjct: 372 AHLCEIFEEINEDALKGTLTHPTQQFVGLR 401 >emb|CAB43933.1| (Y17726) pyruvate ferredoxin oxidoreductase [Clostridium pasteurianum] Length = 1175 Score = 165 bits (413), Expect = 9e-40 Identities = 119/390 (30%), Positives = 200/390 (50%), Gaps = 16/390 (4%) Query: 3 IRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELD-----AEFIKVE 57 I M NEAAA+A+ A +V A +PITPST + E + E+ A+ + + ++++ Sbjct: 4 IMKTMDGNEAAAYAS-YAFTEVAAIYPITPSTPMAESVDEWSAHDKKNIFDQAVNVVEMQ 62 Query: 58 SEHSAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PIN 116 SE A ++ G+ AAG T T TASQGL LM ++ AG +LP V + RA++ ++ Sbjct: 63 SEAGAAGSVHGSLAAGALTTTYTASQGLLLMIPNMYKIAGEQLPTVFHVSARAIATHALS 122 Query: 117 IWNDWQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTV 176 I+ D QD ++ R TG+ + + QEA+DL +++ +V P + FD F +H Sbjct: 123 IFGDHQDVMACRQTGFALLASSSVQEAMDLGCISHLSTIKSKV--PFLHFFDGFRTSHEY 180 Query: 177 EPVEIPDQEVVDEFLGEY----EPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENA 232 + +EI D E + + +Y E + L+P+ P+ +GT P Y + R + + Sbjct: 181 QKIEIIDYEDLKNLV-DYNSIKEFRDKALNPEHPVVRGTAQNPDIYFQGREASNKFYDAV 239 Query: 233 RKVIDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGA 292 +++ E + GR+Y + Y DAE I + MGS+ T+ + +D R +G KVG Sbjct: 240 PDIVENYMKEIKSITGREYHPFDYYGAPDAENIIIAMGSVCDTIDESIDYLRNKGEKVGV 299 Query: 293 AKMTVYRPFPVEEIRELAKKT-KVLAFIEKDISMG-LYGAVFTDASAALINESEKPLMLD 350 K+ +YRPF + + KT K +A +++ G L ++ D N +EKP+++ Sbjct: 300 IKVHLYRPFSSKYFFNVFPKTVKKIAVLDRTKEPGSLAEPLYLDVVHLFNNSAEKPIIIG 359 Query: 351 FIAGLGGRDVTFNQLDEALSIAKEALEKGK 380 GLG +D +Q+ + K K K Sbjct: 360 GRYGLGSKDTRPSQILSVFNNLKSDNPKDK 389 >gb|AAD55756.1|AF132673_1 (AF132673) pyruvate:ferredoxin oxidoreductase [Clostridium pasteurianum] Length = 1098 Score = 162 bits (407), Expect = 5e-39 Identities = 110/364 (30%), Positives = 192/364 (52%), Gaps = 16/364 (4%) Query: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDA-----EFIKVESEHS 61 M NEAAA+A+ A +V A +PITPST + E + E+ A+ + + ++++SE Sbjct: 6 MDGNEAAAYAS-YAFTEVAAIYPITPSTPMAESVDEWSAHDKKNVFDQAVNVVEMQSEAG 64 Query: 62 AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWND 120 A ++ G+ AAG T T TASQGL LM ++ AG +LP V + RA++ ++I+ D Sbjct: 65 AAGSVHGSLAAGALTTTYTASQGLLLMIPNMYKIAGEQLPTVFHVSARAIATHALSIFGD 124 Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 QD ++ R TG+ + + QEA+DL +++ +V P + FD F +H ++ +E Sbjct: 125 HQDVMACRQTGFALLASSSVQEAMDLGCISHLSTIKSKV--PFLHFFDGFRTSHEIQKIE 182 Query: 181 IPDQEVVDEFLGEYEPKHAY----LDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVI 236 + D E + + + + A+ L+P+ P+T+GT P Y + R + +++ Sbjct: 183 VIDYEDLRPLV-DIDAVKAFRNNALNPEHPVTRGTAENPDVYFQGREASNKYYNAIPELV 241 Query: 237 DEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMT 296 + E K GR+Y Y +DAE I + MGS++ +++ +D +G KVG K+ Sbjct: 242 ENYMGEISKITGREYHLFNYYGAEDAERIIIAMGSISDAIEETIDYLNAKGEKVGVLKVH 301 Query: 297 VYRPFPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLMLDFIAG 354 ++RPF VE + + K K +A +++ G YG ++ D A P+++ G Sbjct: 302 LFRPFSVEHFFKYIPKTVKKIAVLDRTKEPGSYGEPLYLDVVTAFYQSDLNPVIVGGRYG 361 Query: 355 LGGR 358 LG + Sbjct: 362 LGSK 365 >emb|CAB43935.1| (Y17727) pyruvate ferredoxin oxidoreductase [Clostridium pasteurianum] Length = 1175 Score = 159 bits (397), Expect = 7e-38 Identities = 112/365 (30%), Positives = 185/365 (50%), Gaps = 16/365 (4%) Query: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELD-----AEFIKVESEHS 61 M N AAA A A V A +PITPS+ + E + E+ G + + ++++SE Sbjct: 7 MDGNTAAAHIA-YAFTDVTAIYPITPSSPMAEHVDEWAVQGRKNLFGQTVKVMEMQSEAG 65 Query: 62 AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAP-INIWND 120 A A+ G+ AG T T TASQGL LM ++ AG LP V + RAL+ +NI+ D Sbjct: 66 AAGAVHGSLQAGALTTTFTASQGLLLMIPNMYKIAGELLPGVFHVSARALATKSLNIFGD 125 Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 QD ++ R TG+ + QE +DL +A+ A +V P + FD F +H ++ +E Sbjct: 126 HQDVMAARQTGFALLAEGSVQEVMDLSAVAHLAAIKGKV--PFLNFFDGFRTSHEIQKIE 183 Query: 181 IPDQEVVDEFLGEYEPKHAY----LDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVI 236 + D E + + + + A+ L+P+ P+T+GT P Y + R + +++ Sbjct: 184 VIDYEDLRPLV-DIDAVKAFRNNALNPEHPVTRGTAENPDVYFQGREASNKYYNAIPELV 242 Query: 237 DEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMT 296 + E K GR+Y Y +DAE I + MGS++ +++ +D +G KVG K+ Sbjct: 243 ENYMGEISKITGREYHLFNYYGAEDAERIIIAMGSISDAIEETIDYLNAKGEKVGVLKVH 302 Query: 297 VYRPFPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLMLDFIAG 354 ++RPF VE + + K K +A +++ G YG ++ D A P+++ G Sbjct: 303 LFRPFSVEHFFKYIPKTVKKIAVLDRTKEPGSYGEPLYLDVVTAFYQSDLNPVIVGGRYG 362 Query: 355 LGGRD 359 LG +D Sbjct: 363 LGSKD 367 >pir||A81294 pyruvate-flavodoxin oxidoreductase Cj1476c [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968902|emb|CAB73898.1| (AL139078) pyruvate-flavodoxin oxidoreductase [Campylobacter jejuni] Length = 1186 Score = 151 bits (377), Expect = 2e-35 Identities = 118/393 (30%), Positives = 193/393 (49%), Gaps = 21/393 (5%) Query: 3 IRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGE-----LDAEFIKVE 57 I M NEAAA+AA A +V +PITPS+ + + + A G+ + + ++++ Sbjct: 4 IMKTMDGNEAAAYAA-YAFTEVAGIYPITPSSPMADYTDMWAAAGKKNLFGVPVKIVEMQ 62 Query: 58 SEHSAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAP-IN 116 SE A ++ G+ AG T T TASQGL L ++ AG LP V+ + R+L+A ++ Sbjct: 63 SEAGAAGSVHGSLQAGALTTTYTASQGLLLKIPNMYKIAGQLLPCVIHVAARSLAAQALS 122 Query: 117 IWNDWQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTV 176 I+ D QD + R G+ + + QE +DL +A+ A RV P + FD F +H + Sbjct: 123 IFGDHQDIYAARQIGFAMLCSHSVQETMDLAGVAHLAAIKGRV--PFLHFFDGFRTSHEI 180 Query: 177 EPVEIPDQEVVDEFLGE---YEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENAR 233 + VE+ D D L E ++ L+P+ P T+GT Y + R + + Sbjct: 181 QKVEVMDYAHFDRLLDREALLEFRNNALNPENPKTRGTAQNDDIYFQTREVSNRFYDALP 240 Query: 234 KVIDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAA 293 V++E E K GR+Y+ Y + E + V MGS+ L++ VD +G KVG Sbjct: 241 DVVNEYMQEISKITGREYKPFTYYGHKEPECVIVAMGSVTQALEEVVDYLNAKGEKVGIL 300 Query: 294 KMTVYRPFPVEEIRE-LAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLMLDF 351 K+ +YRPF ++ + + K K +A +++ G G ++ D +A P+++ Sbjct: 301 KVYLYRPFSLKYFFDVMPKSVKKIAVLDRTKEPGSLGEPLYLDVKSAFYGRENAPVIVGG 360 Query: 352 IAGLGGRDVTFNQLDEALSIAKEALEKGKVEKP 384 GL +DV D A IA E K++ P Sbjct: 361 RYGLSSKDV-----DPAQMIA--VFENLKLDNP 386 >sp|P19543|NIFJ_ENTAG PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|469077|emb|CAA55302.1| (X78558) nifJ [Pantoea agglomerans] >gi|1480137|emb|CAA68011.1| (X99694) nifJ [Enterobacter agglomerans] Length = 1173 Score = 150 bits (374), Expect = 3e-35 Identities = 107/365 (29%), Positives = 178/365 (48%), Gaps = 14/365 (3%) Query: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELD-----AEFIKVESEHS 61 M N AAA+ + A V A +PITPST + E + E+ A G+ + + ++++SE Sbjct: 8 MDGNTAAAYVS-YAFTDVTAIYPITPSTPMAESVDEWAAQGKKNLFGQTVKIMEMQSESG 66 Query: 62 AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWND 120 A A+ GA AG T TASQGL LM ++ AG LP V + RAL+ +NI+ D Sbjct: 67 AAGAIHGALQAGALATTYTASQGLLLMTPNMYKIAGELLPAVFHVSARALATNSLNIFGD 126 Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 QD+ + R TG + Q+ +DL +A+ A R+ P + FD F +H ++ +E Sbjct: 127 HQDSYAVRHTGCAMLAESSVQQVMDLAAVAHLTAIKGRI--PFINFFDGFRTSHEIQKIE 184 Query: 181 IPDQEVVDEFLGE---YEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVID 237 + D E + L + L P P+ +GT P Y + R + ++++ Sbjct: 185 VLDYEDLAHLLDRDAVARFRQNALHPDHPVVRGTAQNPDIYFQEREASNKFYMALPEMVE 244 Query: 238 EAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTV 297 A+ GR+Y Y DA + + MGS+ T+++ VD G KVG + + Sbjct: 245 SYMAKISALTGREYHLFNYYGAPDAGRMIIAMGSVCETIQETVDYLNARGEKVGVLTVHL 304 Query: 298 YRPFPVEE-IRELAKKTKVLAFIEKDISMG-LYGAVFTDASAALINESEKPLMLDFIAGL 355 YRPF ++ + + K +A +++ G L ++ D +A N +P+++ L Sbjct: 305 YRPFSLKHFFKYIPKSVSNIAVLDRTKEPGSLAEPLYLDVKSAFYNSDWRPVIVGGRYAL 364 Query: 356 GGRDV 360 GG+D+ Sbjct: 365 GGKDI 369 >sp|P03833|NIFJ_KLEPN PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|43821|emb|CAA31665.1| (X13303) nifJ protein (AA 1-1171) [Klebsiella pneumoniae] Length = 1171 Score = 148 bits (370), Expect = 1e-34 Identities = 109/370 (29%), Positives = 176/370 (47%), Gaps = 14/370 (3%) Query: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELD-----AEFIKVESEHS 61 M N AAAW + A +V A +PITPST + E + E+ A G+ + ++++SE Sbjct: 8 MDGNAAAAWIS-YAFTEVAAIYPITPSTPMAENVDEWAAQGKKNLFGQPVRLMEMQSEAG 66 Query: 62 AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWND 120 A A+ GA AG T T TASQGL LM ++ AG LP V + RAL+ +NI+ D Sbjct: 67 AAGAVHGALQAGALTTTYTASQGLLLMIPNMYKIAGELLPGVFHVSARALATNSLNIFGD 126 Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 QD ++ R TG N Q+ +DL +A+ A R+ P + FD F +H ++ +E Sbjct: 127 HQDVMAVRQTGCAMLAENNVQQVMDLSAVAHLAAIKGRI--PFVNFFDGFRTSHEIQKIE 184 Query: 181 IPDQEVVDEFLGE---YEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVID 237 + + E + L + L P P+ +GT P Y + R + +++ Sbjct: 185 VLEYEQLATLLDRPALDSFRRNALHPDHPVIRGTAQNPDIYFQEREAGNRFYQALPDIVE 244 Query: 238 EAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTV 297 + GR+Y DAE + + MGS+ T+++ VD G KVG + + Sbjct: 245 SYMTQISALTGREYHLFNYTGAADAERVIIAMGSVCDTVQEVVDTLNAAGEKVGLLSVHL 304 Query: 298 YRPFPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLMLDFIAGL 355 +RPF + +L K + +A +++ G + D A + + PL++ L Sbjct: 305 FRPFSLAHFFAQLPKTVQRIAVLDRTKEPGAQAEPLCLDVKNAFYHHDDAPLIVGGRYAL 364 Query: 356 GGRDVTFNQL 365 GG+DV N + Sbjct: 365 GGKDVLPNDI 374 >pir||QQKBFP pyruvate (flavodoxin) dehydrogenase nifJ (EC 1.2.99.-) - Klebsiella pneumoniae >gi|43863|emb|CAA31501.1| (X13109) pyruvate-flavodoxin oxidoreductase [Klebsiella pneumoniae] Length = 1171 Score = 148 bits (370), Expect = 1e-34 Identities = 109/370 (29%), Positives = 176/370 (47%), Gaps = 14/370 (3%) Query: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELD-----AEFIKVESEHS 61 M N AAAW + A +V A +PITPST + E + E+ A G+ + ++++SE Sbjct: 8 MDGNAAAAWIS-YAFTEVAAIYPITPSTPMAENVDEWAAQGKKNLFGQPVRLMEMQSEAG 66 Query: 62 AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWND 120 A A+ GA AG T T TASQGL LM ++ AG LP V + RAL+ +NI+ D Sbjct: 67 AAGAVHGALQAGALTTTYTASQGLLLMIPNMYKIAGELLPGVFHVSARALATNSLNIFGD 126 Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 QD ++ R TG N Q+ +DL +A+ A R+ P + FD F +H ++ +E Sbjct: 127 HQDVMAVRQTGCAMLAENNVQQVMDLSAVAHLAAIKGRI--PFVNFFDGFRTSHEIQKIE 184 Query: 181 IPDQEVVDEFLGE---YEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVID 237 + + E + L + L P P+ +GT P Y + R + +++ Sbjct: 185 VLEYEQLATLLDRPALDSFRRNALHPDHPVIRGTAQNPDIYFQEREAGNRFYQALPDIVE 244 Query: 238 EAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTV 297 + GR+Y DAE + + MGS+ T+++ VD G KVG + + Sbjct: 245 SYMTQISALTGREYHLFNYTGAADAERVIIAMGSVCDTVQEVVDTLNAAGEKVGLLSVHL 304 Query: 298 YRPFPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLMLDFIAGL 355 +RPF + +L K + +A +++ G + D A + + PL++ L Sbjct: 305 FRPFSLAHFFAQLPKTVQRIAVLDRTKEPGAQAEPLCLDVKNAFYHHDDAPLIVGGRYAL 364 Query: 356 GGRDVTFNQL 365 GG+DV N + Sbjct: 365 GGKDVLPNDI 374 >pir||G71262 probable pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) TP0939 - syphilis spirochete >gi|3323259|gb|AAC65895.1| (AE001262) pyruvate oxidoreductase [Treponema pallidum] Length = 1184 Score = 145 bits (363), Expect = 7e-34 Identities = 112/376 (29%), Positives = 187/376 (48%), Gaps = 24/376 (6%) Query: 6 VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELD-----AEFIKVESEH 60 +M N A A A +VIA FPITPS+ + E E+ A G + ++++SE Sbjct: 8 MMDGNTAVGHVAH-ALSEVIAIFPITPSSPMGEIADEYSARGRTNIWGTVPTVVELQSEA 66 Query: 61 SAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRAL-SAPINIWN 119 A A+ GA G + T TASQGL LM ++ AG V + RA+ ++ ++I+ Sbjct: 67 GASGAVHGALTTGALSSTFTASQGLLLMIPNMYKIAGELTSAVFHVAARAVATSSLSIFG 126 Query: 120 DWQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPV 179 D QD ++ R TGW + + QEA+D ++A+ + RV P + FD F +H ++ + Sbjct: 127 DHQDVMACRQTGWALLASNSVQEAMDTAVIAHAATLEARV--PFVHFFDGFRTSHEIQKI 184 Query: 180 EIPDQEVVDEFLGEYEPKHAY----LDPKRPITQGTLAFPAHYMEARYLVWEAMENARKV 235 E +V+ + + E HA+ L P++P+ +GT P Y + R V A + Sbjct: 185 EEVSYDVMRAMIDD-ELVHAHRMRGLTPEKPVVRGTAQNPDVYFQVRESVNRYYAVAPSI 243 Query: 236 IDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKM 295 + +A + GR+Y+ + Y DAE + V +GS + +++ VD +G K G K+ Sbjct: 244 VQKAMDRYAALTGRQYRLFDYYGAPDAEKVIVMIGSGSEAVEETVDVLNAQGGKCGLVKV 303 Query: 296 TVYRPFPVE-EIRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALIN-ESEK------- 345 +YRPF E + L K + +A +++ G G ++ D A+ +S+K Sbjct: 304 RLYRPFSAECFVNALPKTVQAIAVLDRTKEPGSLGEPLYEDVRTAIGQMQSQKKCPFTHY 363 Query: 346 PLMLDFIAGLGGRDVT 361 PL+L GLG ++ T Sbjct: 364 PLVLGGRYGLGSKEFT 379 >gb|AAC83148.1| (AF061850) putative pyruvate oxidoreductase; POR [Brachyspira pilosicoli] Length = 275 Score = 143 bits (357), Expect = 3e-33 Identities = 89/262 (33%), Positives = 133/262 (49%), Gaps = 6/262 (2%) Query: 45 ANGELDAEFIKVESEHSAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVM 104 ANG I + EH A GA+ AG R F AT++ GL E L + AG R P+V+ Sbjct: 3 ANGRHTVCMIPGDGEHGAAGICYGATTAGGRVFNATSANGLLFAMEQLPVQAGTRFPMVL 62 Query: 105 AIGNRALSAPINIWNDWQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAM 164 + NR +S P++I D D + +TGWI A Q D + A K+A E+ LP + Sbjct: 63 NVVNRTVSGPLDIKCDQSDIMMALNTGWIIIMAHTTQMVYDFNIFALKIA--EKAKLPII 120 Query: 165 VGFDAFILTHTVEPVEI-PDQEVVDEFLGEYEPKHAYLDP-KRPITQGTLAFPAHYMEAR 222 V D F +H + + + + + V +FLG+Y P+ ++P K P+T G ++ Sbjct: 121 VSSDGFFTSHQKKKIHLFKNDKDVQDFLGKYTPEVTSVEPTKNPVTIGPYMNEDELTGSK 180 Query: 223 YLVWEAMENARKVIDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSL--AGTLKDWV 280 + +A+E++R +I E F EF GRKY IE + + AE+ + GS GTL Sbjct: 181 LQLSQALEDSRAIIAEVFEEFASLSGRKYSPIETHNMEGAEVALMLCGSAYETGTLAVDE 240 Query: 281 DKKREEGYKVGAAKMTVYRPFP 302 +K K+GA +T RPFP Sbjct: 241 MRKANPNLKIGAFAITQIRPFP 262 >emb|CAA70873.1| (Y09702) pyruvate-ferredoxin oxidoreductase [Desulfovibrio africanus] Length = 1232 Score = 138 bits (345), Expect = 9e-32 Identities = 109/364 (29%), Positives = 177/364 (47%), Gaps = 19/364 (5%) Query: 10 NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDA-----EFIKVESEHSAIS 64 N A A A A +V A +PITPS+ + E+ ++ A G + +++SE A Sbjct: 11 NTATAHVA-YAMSEVAAIYPITPSSTMGEEADDWAAQGRKNIFGQTLTIREMQSEAGAAG 69 Query: 65 ALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWNDWQD 123 A+ GA AAG T T TASQGL LM ++ +G LP V + RA++A ++I+ D QD Sbjct: 70 AVHGALAAGALTTTFTASQGLLLMIPNMYKISGELLPGVFHVTARAIAAHALSIFGDHQD 129 Query: 124 TISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPD 183 + R TG+ + + QEA D+ L+A+ A + V P M FD F +H ++ +E+ D Sbjct: 130 IYAARQTGFAMLASSSVQEAHDMALVAHLAAIESNV--PFMHFFDGFRTSHEIQKIEVLD 187 Query: 184 QE-----VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDE 238 V + L E+ K ++P+ P +GT P Y + R ++ E Sbjct: 188 YADMASLVNQKALAEFRAKS--MNPEHPHVRGTAQNPDIYFQGREAANPYYLKVPGIVAE 245 Query: 239 AFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVY 298 + GR Y+ + DAE + V+MGS T+++ ++ +G K+G K+ +Y Sbjct: 246 YMQKVASLTGRSYKLFDYVGAPDAERVIVSMGSSCETIEEVINHLAAKGEKIGLIKVRLY 305 Query: 299 RPFPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESE-KPLMLDFIAGL 355 RPF E L KV+ +++ G G ++ D +A + E P +L GL Sbjct: 306 RPFVSEAFFAALPASAKVITVLDRTKEPGAPGDPLYLDVCSAFVERGEAMPKILAGRYGL 365 Query: 356 GGRD 359 G ++ Sbjct: 366 GSKE 369 >pdb|1B0P|A Chain A, Crystal Structure Of Pyruvate-Ferredoxin Oxidoreductase From Desulfovibrio Africanus >gi|4558092|pdb|1B0P|B Chain B, Crystal Structure Of Pyruvate-Ferredoxin Oxidoreductase From Desulfovibrio Africanus >gi|4558221|pdb|2PDA|A Chain A, Crystal Structure Of The Complex Between Pyruvate- Ferredoxin Oxidoreductase From Desulfovibrio Africanus And Pyruvate. >gi|4558222|pdb|2PDA|B Chain B, Crystal Structure Of The Complex Between Pyruvate- Ferredoxin Oxidoreductase From Desulfovibrio Africanus And Pyruvate Length = 1231 Score = 138 bits (345), Expect = 9e-32 Identities = 109/364 (29%), Positives = 177/364 (47%), Gaps = 19/364 (5%) Query: 10 NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDA-----EFIKVESEHSAIS 64 N A A A A +V A +PITPS+ + E+ ++ A G + +++SE A Sbjct: 10 NTATAHVA-YAMSEVAAIYPITPSSTMGEEADDWAAQGRKNIFGQTLTIREMQSEAGAAG 68 Query: 65 ALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWNDWQD 123 A+ GA AAG T T TASQGL LM ++ +G LP V + RA++A ++I+ D QD Sbjct: 69 AVHGALAAGALTTTFTASQGLLLMIPNMYKISGELLPGVFHVTARAIAAHALSIFGDHQD 128 Query: 124 TISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPD 183 + R TG+ + + QEA D+ L+A+ A + V P M FD F +H ++ +E+ D Sbjct: 129 IYAARQTGFAMLASSSVQEAHDMALVAHLAAIESNV--PFMHFFDGFRTSHEIQKIEVLD 186 Query: 184 QE-----VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDE 238 V + L E+ K ++P+ P +GT P Y + R ++ E Sbjct: 187 YADMASLVNQKALAEFRAKS--MNPEHPHVRGTAQNPDIYFQGREAANPYYLKVPGIVAE 244 Query: 239 AFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVY 298 + GR Y+ + DAE + V+MGS T+++ ++ +G K+G K+ +Y Sbjct: 245 YMQKVASLTGRSYKLFDYVGAPDAERVIVSMGSSCETIEEVINHLAAKGEKIGLIKVRLY 304 Query: 299 RPFPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESE-KPLMLDFIAGL 355 RPF E L KV+ +++ G G ++ D +A + E P +L GL Sbjct: 305 RPFVSEAFFAALPASAKVITVLDRTKEPGAPGDPLYLDVCSAFVERGEAMPKILAGRYGL 364 Query: 356 GGRD 359 G ++ Sbjct: 365 GSKE 368 >emb|CAA57480.1| (X81893) nifJ [Enterobacter agglomerans] Length = 308 Score = 138 bits (344), Expect = 1e-31 Identities = 96/304 (31%), Positives = 150/304 (48%), Gaps = 12/304 (3%) Query: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELD-----AEFIKVESEHS 61 M N AAA+ + A V A +PITPST + E + E+ A G+ + + ++++SE Sbjct: 8 MDGNTAAAYVS-YAFTDVTAIYPITPSTPMAESVDEWAAQGKKNLFGQTVKVMEMQSESG 66 Query: 62 AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWND 120 A A+ GA AG T TASQGL LM ++ AG LP V + RAL+ +NI+ D Sbjct: 67 AAGAIHGALQAGALATTYTASQGLLLMTPNMYKIAGELLPAVFHVSARALATNSLNIFGD 126 Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 QD ++ R TG + Q+ +DL +A+ A R+ P + FD F +H ++ +E Sbjct: 127 HQDVMAVRQTGCAMLAESSVQQVMDLAAVAHLTAIKGRI--PFINFFDGFRTSHEIQKIE 184 Query: 181 IPDQEVVDEFL---GEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVID 237 + D E + L + L P P+ +GT P Y + R + ++++ Sbjct: 185 VLDYEELAALLDWDAVTRFRQNALHPDHPVVRGTAQNPDIYFQEREASNKFYMALPEMVE 244 Query: 238 EAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTV 297 A+ K GR+Y Y DA + + MGS+ T+++ VD G KVG + + Sbjct: 245 SYMAKISKLTGREYHLFNYYGAPDAGRMIIAMGSVCETIQETVDYLNASGEKVGVLTVHL 304 Query: 298 YRPF 301 YRPF Sbjct: 305 YRPF 308 >pir||C70403 ferredoxin oxidoreductase alpha subunit - Aquifex aeolicus >gi|2983644|gb|AAC07211.1| (AE000728) ferredoxin oxidoreductase alpha subunit [Aquifex aeolicus] Length = 404 Score = 138 bits (344), Expect = 1e-31 Identities = 97/337 (28%), Positives = 161/337 (46%), Gaps = 19/337 (5%) Query: 10 NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISALVGA 69 +EA AAK A ++PITP + + E G + F + ESE +S + G Sbjct: 39 SEAVKEAAKRASVDASISYPITPQSEAAHMLGELWREGYIGVYF-RGESEFGVMSEVAGC 97 Query: 70 SAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTISQRD 129 + AG RT T T+ G EV + AG RLPI + + R +++P++I D + D Sbjct: 98 AMAGARTITTTSGPGTMRAMEVFPMWAGSRLPIQLVLMARGINSPLSIQPDNLEISFLLD 157 Query: 130 TGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEVVDE 189 TG + ++AE QE D+I+ + VAE V +P + D F ++HT E V +P +++ Sbjct: 158 TGCMVWHAETAQELFDMIIAGFVVAEQPDVHVPIITAIDGFFISHTREAVYLPPEDIA-- 215 Query: 190 FLGEYEPKHAYLDP-KRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEKKFG 248 L Y P A + P + G M++ Y+ + A + + A E + + Sbjct: 216 -LPPYNPYKAPMPPIDMEMPPGRFMRDPFVMKSNYISY-ATHASWQFEVRAAIERSRPYA 273 Query: 249 RKYQK--IEEYRTDDAEIIFVTMGSLAGTLKDWVD-KKREEGYKVGAAKMTVYRPFPVEE 305 + Y + +E + + E++F+ G+ A K+ EEG K ++ RPFP EE Sbjct: 274 KHYLRGLVEHFGDPEGEVLFIASGTAAAQAKEATQILIHEEGIKARVLRLKTLRPFPTEE 333 Query: 306 IRELAKKTK--------VLAFIEKDISMGLYGAVFTD 334 +RE K K V+ ++E+++ LYG +TD Sbjct: 334 VREAVKGAKYIFIPEFNVVGWLEREVKRALYG--YTD 368 >dbj|BAA95605.1| (AB042412) pyruvate:ferredoxin oxidoreductase alpha subunit [Hydrogenobacter thermophilus] Length = 400 Score = 138 bits (343), Expect = 1e-31 Identities = 93/333 (27%), Positives = 156/333 (45%), Gaps = 14/333 (4%) Query: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAL 66 M +EA A K A ++PITP + I E G + F + ESE +S + Sbjct: 33 MTGSEAVKEAVKRASVDASVSYPITPQSEAAHLIGELWVEGYVGVYF-RGESEFGVMSEI 91 Query: 67 VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTIS 126 G + AG RT T T+ G E + AG R+P+ + + R ++AP++I D + Sbjct: 92 AGCALAGARTITTTSGPGTLRAMENFPMWAGTRIPVQLVLMARGVNAPLSIQPDNLEVSF 151 Query: 127 QRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEV 186 DTG + +YAE Q+ D+IL + VAE V +P + D F ++HT E V +P ++ Sbjct: 152 LLDTGCMIWYAETAQDLFDMILAGFVVAEQPDVHVPVITVVDGFFVSHTRETVMLPPDDI 211 Query: 187 VDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEKK 246 Y +D + P G M++ Y+ + + + + A E + Sbjct: 212 ALPPYNPYRAPMPVIDAEVP--PGRFLRDPFVMKSNYISYATHASWQWEV-RAAIERSRP 268 Query: 247 FGRKYQK--IEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVE 304 + + Y + IE + +A+++FV G+ + K+ V +EG K+ RPFP+E Sbjct: 269 YAKHYLRGLIEHFGDPEADLVFVACGTASAQAKEAVRMLEDEGISARVVKLKTIRPFPIE 328 Query: 305 EIRELAKKTK--------VLAFIEKDISMGLYG 329 E+RE K K V+ ++E+++ LYG Sbjct: 329 ELREATKGAKYIFVPEFNVVGWLEREVRRYLYG 361 >sp|P52647|NIFJ_ECOLI PROBABLE PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|7431614|pir||E64888 probable pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) ydbK - Escherichia coli >gi|1742250|dbj|BAA14982.1| (D90775) Pyruvate-flavodoxin oxidoreductase (EC 1.-.-.-). [Escherichia coli] >gi|1742256|dbj|BAA14987.1| (D90776) Pyruvate-flavodoxin oxidoreductase (EC 1.-.-.-). [Escherichia coli] >gi|1787642|gb|AAC74460.1| (AE000234) putative oxidoreductase, Fe-S subunit [Escherichia coli K12] Length = 1174 Score = 134 bits (335), Expect = 1e-30 Identities = 101/350 (28%), Positives = 167/350 (46%), Gaps = 18/350 (5%) Query: 23 KVIAAFPITPSTLVPEKISEFVANGELDA-----EFIKVESEHSAISALVGASAAGVRTF 77 +VIA +PITPS+ + E+ + NG + ++++SE AI+ + GA G + Sbjct: 19 EVIAIYPITPSSTMAEQADAWAGNGLKNVWGDTPRVVEMQSEAGAIATVHGALQTGALST 78 Query: 78 TATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWNDWQDTISQRDTGWIQFY 136 + T+SQGL LM L+ AG P V+ + R ++ ++I+ D D ++ R TG Sbjct: 79 SFTSSQGLLLMIPTLYKLAGELTPFVLHVAARTVATHALSIFGDHSDVMAVRQTGCAMLC 138 Query: 137 AENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEVVDEFLGEYE- 195 A N QEA D L++ RV P + FD F +H + + + + + + + E Sbjct: 139 AANVQEAQDFALISQIATLKSRV--PFIHFFDGFRTSHEINKIVPLADDTILDLMPQVEI 196 Query: 196 --PKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEKKFGRKYQK 253 + L+P+ P+ +GT A P Y ++R +++A +F GR+YQ Sbjct: 197 DAHRARALNPEHPVIRGTSANPDTYFQSREATNPWYNAVYDHVEQAMNDFSAATGRQYQP 256 Query: 254 IEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVEE-IRELAKK 312 E Y AE + + MGS GT ++ VD+ G KVG K+ +YRPF + ++ L Sbjct: 257 FEYYGHPQAERVIILMGSAIGTCEEVVDELLTRGEKVGVLKVRLYRPFSAKHLLQALPGS 316 Query: 313 TKVLAFIEKDISMG-----LYGAVFTDASAALINESEKPLMLDFIAGLGG 357 + +A +++ G LY V T A A N E+ + I G G Sbjct: 317 VRSVAVLDRTKEPGAQAEPLYLDVMT-ALAEAFNNGERETLPRVIGGRYG 365 >sp|P52965|NIFJ_SYNY3 PUTATIVE PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|7431613|pir||S77082 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) nifJ - Synechocystis sp. (strain PCC 6803) >gi|1006618|dbj|BAA10774.1| (D64005) pyruvate oxidoreductase [Synechocystis sp.] Length = 1199 Score = 134 bits (334), Expect = 2e-30 Identities = 108/372 (29%), Positives = 179/372 (48%), Gaps = 14/372 (3%) Query: 1 MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAE-----FIK 55 +P + NEA A A L +VIA +PITPS+ + E + A + ++ Sbjct: 3 LPTYATLDGNEAVARVAYLLS-EVIAIYPITPSSPMGEWSDAWAAEHRPNLWGTVPLVVE 61 Query: 56 VESEHSAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAP- 114 ++SE A + GA +G T T TASQGL LM + AG +V+ + R+L+A Sbjct: 62 MQSEGGAAGTVHGALQSGALTTTFTASQGLMLMLPNMHKIAGELTAMVLHVAARSLAAQG 121 Query: 115 INIWNDWQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTH 174 ++I+ D D ++ R+TG+ + + QEA D L+A + R+ P + FD F +H Sbjct: 122 LSIFGDHSDVMAARNTGFAMLSSNSVQEAHDFALIATATSFATRI--PGLHFFDGFRTSH 179 Query: 175 TVEPVEIPDQEVVDEFLGEYEP---KHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMEN 231 + +E+ QEV+ + + + + L P RP +GT P Y +AR V + Sbjct: 180 EEQKIELLPQEVLRGLIKDEDVLAHRGRALTPDRPKLRGTAQNPDVYFQARETVNPFYAS 239 Query: 232 ARKVIDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVG 291 V+++ +F + GR Y+ E +AE + V MGS A T ++ VD +G KVG Sbjct: 240 YPNVLEQVMEQFGQLTGRHYRPYEYCGHPEAERVIVLMGSGAETAQETVDFLTAQGEKVG 299 Query: 292 AAKMTVYRPFPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLML 349 K+ +YRPF + + L K + +A +++ G G ++ D A P ++ Sbjct: 300 LLKVRLYRPFAGDRLVNALPKTVQKIAVLDRCKEPGSIGEPLYQDVLTAFFEAGMMPKII 359 Query: 350 DFIAGLGGRDVT 361 GL ++ T Sbjct: 360 GGRYGLSSKEFT 371 >emb|CAB43934.1| (Y17727) pyruvate ferredoxin oxidoreductase [Clostridium pasteurianum] Length = 1181 Score = 133 bits (332), Expect = 3e-30 Identities = 105/366 (28%), Positives = 177/366 (47%), Gaps = 17/366 (4%) Query: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELD-----AEFIKVESEHS 61 M N AAA A A V +PITPS+ + + + + A G+ + + ++++SE Sbjct: 8 MDGNTAAAHVA-YAYTDVAGIYPITPSSPMADSVDMWSAAGQENIFGNQVKVVEMQSEAG 66 Query: 62 AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWND 120 A + G+ AAG T T TASQGL LM ++ AG LP V + R +++ +NI+ D Sbjct: 67 AAGTVHGSLAAGALTTTFTASQGLLLMIPNMYKIAGEMLPSVFHVSARTVASHALNIFGD 126 Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 D + R G+ N QE +DL +A+ A + +V P + FD F +H ++ +E Sbjct: 127 HSDVYACRQVGFAMLAETNPQEVMDLSPVAHLAALEGKV--PFINFFDGFRTSHEIQKIE 184 Query: 181 IPDQEVVDEFLGEYEPK----HAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVI 236 D E + E K HA L+P++P +G+ + + R A N ++ Sbjct: 185 KWDYEDLKEMCNMDAVKAFRDHA-LNPEKPAMRGSHENGDVFFQHREACNTAYNNLPAIV 243 Query: 237 DEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMT 296 ++ A+ +K G Y Y +DA+ + + MGS+ ++ +D +G KVG K+ Sbjct: 244 EKYMAKVNEKLGTDYDLFNYYGAEDADRVIIAMGSICDVAEEVIDYLTAKGEKVGLVKVR 303 Query: 297 VYRPFPVEEI-RELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLMLDF-IA 353 +YRP+ E I + L K K +A +++ G G ++ D + L ++L Sbjct: 304 LYRPWVSESILKALPKTAKKVAVLDRTKEPGALGDPLYLDVATTLREAGLNDIILTAGRY 363 Query: 354 GLGGRD 359 GLG +D Sbjct: 364 GLGSKD 369 >pir||F82447 pyruvate-flavoredoxin oxidoreductase VCA0530 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9657937|gb|AAF96433.1| (AE004384) pyruvate-flavoredoxin oxidoreductase [Vibrio cholerae] Length = 1079 Score = 130 bits (323), Expect = 3e-29 Identities = 100/359 (27%), Positives = 172/359 (47%), Gaps = 22/359 (6%) Query: 6 VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDA-----EFIKVESEH 60 + AN A A A +V+A +PITPST + E ++ + + + + ++++SE Sbjct: 4 ITDANTAVARVAYQLS-EVLAVYPITPSTSMAESCEQWASQQKSNLLGDVPKLVEMQSEA 62 Query: 61 SAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWN 119 +I+ + GA+ +G T T+SQGL LM L+ AG P V+ + R ++ ++I+ Sbjct: 63 GSIAVVHGAAMSGALATTFTSSQGLLLMIPSLYKLAGELTPCVIHVAARTVATHALSIYC 122 Query: 120 DWQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPV 179 D D ++ R TG A N QEA DL +A A R LP + FD F+ +H + + Sbjct: 123 DHSDVMAIRQTGVAMLCASNAQEAQDLAAIATFSALQCR--LPFVHFFDGFLTSHAITQI 180 Query: 180 EIPDQEVVDEFLGEYEPKHAYLD-------PKRPITQGTLAFPAHYMEARYLVWEAMENA 232 E +E + L P A +D P RP +G A P Y + R ++ Sbjct: 181 EPLSEEALSALL----PMPALVDFRTRVLTPDRPTLRGATADPDSYFQCREAQTPYHQST 236 Query: 233 RKVIDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGA 292 + + FE + GR+YQ E A+ + V MGS T+K V ++G ++G Sbjct: 237 PEQVQNIMDCFETQTGRRYQLAEYIGHPQAQSVIVAMGSSVDTIKQVVLAGVQQGERIGV 296 Query: 293 AKMTVYRPFPVEEIRELAKKTKV-LAFIEKDISMGLYG-AVFTDASAALINESEKPLML 349 ++ +YRPFP + +R+ T ++ +++ G +G ++ D +AL + + L Sbjct: 297 IQIRLYRPFPSQALRDALPATVTHISVLDRTKEPGSHGEPLYLDVLSALYTQRANSIRL 355 >pir||B70400 ferredoxin oxidoreductase alpha subunit - Aquifex aeolicus >gi|2983615|gb|AAC07184.1| (AE000726) ferredoxin oxidoreductase alpha subunit [Aquifex aeolicus] Length = 389 Score = 129 bits (322), Expect = 4e-29 Identities = 103/378 (27%), Positives = 166/378 (43%), Gaps = 32/378 (8%) Query: 10 NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISALVGA 69 ++A A A K A V A+PITP + + + A G + ++ + E E+ A+SA+ GA Sbjct: 26 SQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVK-DYYRAEEEYGAMSAIAGA 84 Query: 70 SAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTISQRD 129 G R FTAT+ GL E + G R+P V+ + R ++AP++I D + + Sbjct: 85 VRGGARAFTATSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVEISYLLN 144 Query: 130 TGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEVV-- 187 +G + +AEN Q+ D L + ++E V LP +V + F +TH VE+P +++ Sbjct: 145 SGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELPPEDMKLP 204 Query: 188 --DEFLGEYEPKHAYLDPKR-----PITQGTLAFPAHYMEARYLVWEAMENARKVIDEAF 240 D + P + P R P+ + + + VW A A K I Sbjct: 205 PRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQQEVWSANRRAAKWIKHYL 264 Query: 241 AEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300 + E DAE+ V G A ++ EG VG K+ RP Sbjct: 265 G-----------GLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIKVKSLRP 313 Query: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGR-- 358 FPV+EIRE K K + E +I G + + AA+ N +++D GG Sbjct: 314 FPVDEIREALKNAKAVIVPEHNI----VGWLAKEVKAAIPNSG---IVVDGPRVYGGMTL 366 Query: 359 --DVTFNQLDEALSIAKE 374 ++ ++ +A I KE Sbjct: 367 PVELIMEEIYKAFGIKKE 384 >sp|Q06879|NIFJ_ANASP PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|2126544|pir||I39613 pyruvate (flavodoxin) dehydrogenase nifJ (EC 1.2.99.-) - Anabaena sp >gi|289139|gb|AAC36818.1| (L14925) nitrogen fixation protein [Anabaena sp.] Length = 1197 Score = 123 bits (307), Expect = 2e-27 Identities = 104/359 (28%), Positives = 173/359 (47%), Gaps = 29/359 (8%) Query: 10 NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDA-----EFIKVESEHSAIS 64 NEA A A +VIA +PITPS+ + E ++A G + ++++SE A Sbjct: 11 NEAVARVAYKLN-EVIAIYPITPSSAMGEWADAWMAEGRPNLWGTVPSVVQMQSEGGAAG 69 Query: 65 ALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWNDWQD 123 A+ GA G + T TASQGL LM L+ G +V+ + R+L+ ++I+ D D Sbjct: 70 AVHGALQTGSLSTTFTASQGLLLMIPNLYKIGGELTSMVVHVAARSLATHALSIFGDHSD 129 Query: 124 TISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPD 183 ++ R TG+ + + QE+ D L+A+ D RV + FD F +H V+ VE+ Sbjct: 130 VMAARGTGFAMLCSASVQESHDFALIAHAATLDTRVSF--LHFFDGFRTSHEVQKVELLA 187 Query: 184 QEVVDEFLGE---YEPKHAYLDPKRPITQGTLAFPAHYMEAR------YLVWEAMENARK 234 + V + E + + L P P+ +GT P + +AR Y A+ + Sbjct: 188 DDDVRSLINEDKIFAHRARALTPDSPLLRGTAQNPDVFFQAREGANPYYNACPAI--VQG 245 Query: 235 VIDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAK 294 ++D+ F E + GR YQ E + DA+ + + MGS T+ + VD G KVG K Sbjct: 246 IMDKFFGE---RTGRYYQIYEYHGASDADRLIIIMGSGCETVHETVDYLNARGEKVGVLK 302 Query: 295 MTVYRPFPVEE-IRELAKKTKVLAFIEKDISMG-----LYGAVFTDASAALINESEKPL 347 + ++RP+ VE ++ L + +A +++ G LY V T +N++ P+ Sbjct: 303 VRLFRPWDVERFVQALPHSVQAIAVLDRTKEPGSAGEPLYQDVVTAIHEGWVNKNNSPV 361 >gb|AAD55754.1|AF132546_1 (AF132546) pyruvate:ferredoxin oxidoreductase [Spironucleus barkhanus] Length = 1182 Score = 119 bits (296), Expect = 5e-26 Identities = 89/289 (30%), Positives = 145/289 (49%), Gaps = 13/289 (4%) Query: 28 FPITPSTLVPEKISEFVANGELDA-----EFIKVESEHSAISALVGASAAGVRTFTATAS 82 FPI+PS+ + E + E+ + G L+A ++ E A AL GA G + T TAS Sbjct: 21 FPISPSSPMAELVDEWASKGRLNAFDQVHRVTELNHEGGAAGALHGALLNGSLSSTYTAS 80 Query: 83 QGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWNDWQDTISQRDTGWIQFYAENNQ 141 QGL LM L+ A LP V+ + R ++ ++I D D ++ + TG + + Q Sbjct: 81 QGLLLMIPNLYKMAAEHLPGVLHVAARTIATHSLSIHGDHSDIMAIKQTGISILVSPDVQ 140 Query: 142 EALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEVVDEFLGEYEP----K 197 EA+D L+A+ A + P + FD + +HT++ VE+ + + F+ YE + Sbjct: 141 EAMDFALVAHIAAINADT--PFIHAFDGYRTSHTIKKVEVISYDKIKPFV-PYEKIAEFR 197 Query: 198 HAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEKKFGRKYQKIEEY 257 H L+ +RP G+ P +M+++ ++AF EK GRKY+ I+ + Sbjct: 198 HKSLNSQRPEAYGSCMGPPVWMQSQEADNLHYSKILGHFEDAFVTVEKITGRKYEVIQYH 257 Query: 258 RTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVEEI 306 DA + V MGS T+++ VD +G KVGA + ++RPFP I Sbjct: 258 GCADATDVIVIMGSGCITVRETVDYLNAQGRKVGAIFINLFRPFPSAHI 306 >dbj|BAB12024.1| (AB021127) pyruvate:NADP+ oxidoreductase [Euglena gracilis] Length = 1803 Score = 115 bits (286), Expect = 7e-25 Identities = 98/345 (28%), Positives = 165/345 (47%), Gaps = 15/345 (4%) Query: 28 FPITPSTLVPEKISEFVANGELDA-----EFIKVESEHSAISALVGASAAGVRTFTATAS 82 +PITPS+++ E ++A G +A + +++SE A AL GA AAG T TAS Sbjct: 92 YPITPSSVMGELADVWMAQGRKNAFGQVVDVREMQSEAGAAGALHGALAAGAIATTFTAS 151 Query: 83 QGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWNDWQDTISQRDTGWIQFYAENNQ 141 QGL LM ++ AG +P V+ + R L+ ++I+ D ++ R TGW + Q Sbjct: 152 QGLLLMIPNMYKIAGELMPSVIHVAARELAGHALSIFGGHADVMAVRQTGWAMLCSHTVQ 211 Query: 142 EALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEVVDEFL--GEYEPKHA 199 ++ D+ L+++ + P + FD F +H V +++ + + + G E A Sbjct: 212 QSHDMALISHVATLKSSI--PFVHFFDGFRTSHEVNKIKMLPYAELKKLVPPGTMEQHWA 269 Query: 200 Y-LDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEKKFGRKYQKIEEYR 258 L+P P +GT Y + + + +V+ E E GR Y+ E Sbjct: 270 RSLNPMHPTIRGTNQSADIYFQNMESANQYYTDLAEVVQETMDEVAPYIGRHYKIFEYVG 329 Query: 259 TDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVEEIRELAKKT-KVLA 317 DAE + V MGS A T+ + VD + G KVGA + +YRP+ + ++ KT K +A Sbjct: 330 APDAEEVTVLMGSGATTVNEAVDLLVKRGKKVGAVLVHLYRPWSTKAFEKVLPKTVKRIA 389 Query: 318 FIEKDISMGLYG-AVFTDASAA--LINESEKPLMLDFIAGLGGRD 359 +++ + G ++ D SA L E + ++ GLG +D Sbjct: 390 ALDRCKEVTALGEPLYLDVSATLNLFPERQNVKVIGGRYGLGSKD 434 >gb|AAB49653.1| (U30149) pyruvate:ferredoxin oxidoreductase [Entamoeba histolytica] Length = 1162 Score = 115 bits (285), Expect = 9e-25 Identities = 100/386 (25%), Positives = 176/386 (44%), Gaps = 21/386 (5%) Query: 10 NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDA-----EFIKVESEHSAIS 64 N+AAA+ + A V FPITPS+ + E + + G + + ++ESE A Sbjct: 7 NQAAAYVS-YALSDVSFIFPITPSSPMAENADVWSSQGRKNVFGQVVDVYEMESEAGASG 65 Query: 65 ALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAP-INIWNDWQD 123 A+ G AAG T T SQGL LM + AG LP V + RAL+ ++I+ D D Sbjct: 66 AVHGGCAAGSLVSTYTCSQGLMLMIPNMIKIAGEHLPCVFHVTARALAGQALSIFGDHSD 125 Query: 124 TISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPD 183 ++ R TG+ + N Q+ DL ++A+ + LP M FD F +H ++ + Sbjct: 126 VMACRSTGFCLLSSHNVQQCHDLAIVAHLATLEAS--LPFMHFFDGFRTSHEIQKIHQLT 183 Query: 184 QEVVDEFLGEYEPKHAY---LDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAF 240 + + + A+ L+P P +GT P + +A +++ + Sbjct: 184 YDQIKSLVDMKYVDRAHKRGLNPIHPSQRGTSQGPDVFFQAVEKSNADYLKVPEIVQKYM 243 Query: 241 AEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300 + + GR Y+ E Y DAE + V MG+ L++ VD + G KVG + +YRP Sbjct: 244 DKVGELTGRHYKIFEYYGAADAERVVVVMGAAVPVLEECVDYLMKSGEKVGVLSVHLYRP 303 Query: 301 FPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLMLDFIAGLGGR 358 + + + +L ++ +++ G +G ++ D + L++ + + GLG + Sbjct: 304 WSAKHFLEQLPNTVTKISVLDRTKEAGSFGEPLYLDVATTLLDAGKHIKCVGGRYGLGSK 363 Query: 359 DVTFNQLDEALSIAKEALEKGKVEKP 384 + T ++AK + K E+P Sbjct: 364 EFT-------PAMAKAVFDNLKNEEP 382 >sp|Q53046|NIFJ_RHORU PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|628896|pir||S41961 pyruvate oxidoreductase - Rhodospirillum rubrum >gi|453436|emb|CAA54651.1| (X77515) pyruvate oxidoreductase [Rhodospirillum rubrum] Length = 1191 Score = 113 bits (280), Expect = 4e-24 Identities = 101/363 (27%), Positives = 165/363 (44%), Gaps = 18/363 (4%) Query: 10 NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDA-----EFIKVESEHSAIS 64 NEA A A +V +PITPS+ + E E+ A G + + ++++SE A Sbjct: 12 NEACASVAYRVS-EVAVIYPITPSSTMGELSDEWSAKGLTNIWGAVPQVVEMQSEGGAAG 70 Query: 65 ALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWNDWQD 123 A GA G T TASQGL LM ++ AG P M + R L+ ++I+ D D Sbjct: 71 ACHGAIQTGSLGTTFTASQGLLLMIPNMYKIAGELTPFCMHVTARTLATHALSIFGDQSD 130 Query: 124 TISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPD 183 ++ R TG+ + + QEA DL +A+ + + R+ P + FD F +H V +E+ Sbjct: 131 VMACRQTGFAILASASVQEAHDLASVAHGASLESRI--PFLHFFDGFRTSHEVNKIELMT 188 Query: 184 QE----VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEA 239 + ++D+ L A L P P+T+GT P + +A+ + ++ Sbjct: 189 DDDLHAMIDDDLVAAHRARA-LTPDTPVTRGTAQNPDTFFQAQEARNPFYDACPAIVQSY 247 Query: 240 FAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYR 299 GR+Y + AE + V MGS A T+ + VD G K+G K+ ++R Sbjct: 248 MDRLAALTGRRYGLFDYVGHPQAERVVVIMGSGAETVAETVDWLVARGEKIGVVKVRLFR 307 Query: 300 PFPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLMLDFI--AGL 355 PF V+ + L + +A +++ G G ++ D AL L + A + Sbjct: 308 PFSVDAFVAALPVSVRAIAVLDRCKESGAIGEPLYLDVVGALARAKALGLRAGIVDPAVI 367 Query: 356 GGR 358 GGR Sbjct: 368 GGR 370 >pir||S70963 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) - Rhodospirillum rubrum Length = 1191 Score = 113 bits (280), Expect = 4e-24 Identities = 101/363 (27%), Positives = 165/363 (44%), Gaps = 18/363 (4%) Query: 10 NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDA-----EFIKVESEHSAIS 64 NEA A A +V +PITPS+ + E E+ A G + + ++++SE A Sbjct: 12 NEACASVAYRVS-EVAVIYPITPSSTMGELSDEWSAKGLTNIWGAVPQVVEMQSEGGAAG 70 Query: 65 ALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWNDWQD 123 A GA G T TASQGL LM ++ AG P M + R L+ ++I+ D D Sbjct: 71 ACHGAIQTGSLGTTFTASQGLLLMIPNMYKIAGELTPFCMHVTARTLATHALSIFGDQSD 130 Query: 124 TISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPD 183 ++ R TG+ + + QEA DL +A+ + + R+ P + FD F +H V +E+ Sbjct: 131 VMACRQTGFAILASASVQEAHDLASVAHGASLESRI--PFLHFFDGFRTSHEVNKIELMT 188 Query: 184 QE----VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEA 239 + ++D+ L A L P P+T+GT P + +A+ + ++ Sbjct: 189 DDDLHAMIDDDLVAAHRARA-LTPDTPVTRGTAQNPDTFFQAQEARNPFYDACPAIVQSY 247 Query: 240 FAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYR 299 GR+Y + AE + V MGS A T+ + VD G K+G K+ ++R Sbjct: 248 MDRLAALTGRRYGLFDYVGHPQAERVVVIMGSGAETVAETVDWLVARGEKIGVVKVRLFR 307 Query: 300 PFPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLMLDFI--AGL 355 PF V+ + L + +A +++ G G ++ D AL L + A + Sbjct: 308 PFSVDAFVAALPVSVRAIAVLDRCKESGAIGEPLYLDVVGALARAKALGLRAGIVDPAVI 367 Query: 356 GGR 358 GGR Sbjct: 368 GGR 370 >pir||H72214 hypothetical protein TM1759 - Thermotoga maritima (strain MSB8) >gi|4982338|gb|AAD36824.1|AE001814_6 (AE001814) 2-oxoisovalerate oxidoreductase, beta subunit, putative [Thermotoga maritima] Length = 356 Score = 112 bits (277), Expect = 8e-24 Identities = 100/343 (29%), Positives = 155/343 (45%), Gaps = 36/343 (10%) Query: 4 RTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANG--ELDAEFIKVESEHS 61 + +MK NEA A +A A ++ A+PITP + +I+E++A E+ F++ ESE + Sbjct: 6 KLMMKGNEAIAESAIRAGCRLYFAYPITPQS----EIAEYMARRLPEVGGVFLQTESEIA 61 Query: 62 AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDW 121 ++ + GA+ G R T+T+S G +LM E + AG LP V R NI Sbjct: 62 TVNMVYGAACTGKRVMTSTSSPGFSLMQEGISYIAGAELPCVFVDVVRGGPGLGNIQPSQ 121 Query: 122 QDTIS------QRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHT 175 D D I QEA+DL LA+ +A+ R P ++ D I Sbjct: 122 GDYFQAVKGGGHGDYRLIVLAPSTLQEAVDLTQLAFDLAD--RYRNPVLILADGMI-GQM 178 Query: 176 VEPVEIPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKV 235 +EPVE+P+ + P H+ +G H + A + +E K Sbjct: 179 MEPVELPEMRDLSTL-----PDHSDW-----ALRGARNREPHRIAAFNIDPVGLEKMNKR 228 Query: 236 IDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKM 295 + E + E Q+ EEYR D AE + V G++ LK VD REEG G + Sbjct: 229 LQEKYRLIEAS----EQRWEEYRVDGAEYLMVGYGTMGRILKSVVDSLREEGIPAGLFRP 284 Query: 296 TVYRPFPVEEIRELAKKTKVLAFIE-------KDISMGLYGAV 331 PFP ++ELAKK +++ +E +D+ + + G V Sbjct: 285 VTLWPFPKRRLKELAKKVQLIFVVEMSSGQMVEDVQISVEGKV 327 >pir||T43259 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) pfoB precursor, hydrogenosomal - Trichomonas vaginalis >gi|622960|gb|AAA85495.1| (U16823) pyruvate:ferredoxin oxidoreductase proprotein [Trichomonas vaginalis] Length = 1157 Score = 111 bits (276), Expect = 1e-23 Identities = 97/335 (28%), Positives = 156/335 (45%), Gaps = 33/335 (9%) Query: 28 FPITPSTLVPEKISEFVANGELDAEFIKV-----ESEHSAISALVGASAAGVRTFTATAS 82 +PITP+T + E + ++A G + KV +SE A +A+ GA+A G T TAS Sbjct: 31 YPITPATTMGELVDAWIAQGRKNIWGNKVNMAMMQSEGGAAAAVHGATAVGALCATFTAS 90 Query: 83 QGLALMHEVLFIAAGMRLPIVMAIGNRAL-SAPINIWNDWQDTISQRDTGWIQFYAENNQ 141 QG LM ++ G P V I R + ++ ++I+ND D + R TG ++ Q Sbjct: 91 QGALLMIPDMYKIVGEMCPAVFHIAARCIATSALSIYNDHGDIYACRATGMPILFSNGVQ 150 Query: 142 EALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEVV-----DEFLGEYEP 196 EA DL +A+ + LP + FD F +H + E D E + + L + Sbjct: 151 EAHDLAAVAHLTS--IHTGLPFIHTFDGFRTSHEINTYEELDNETLWPLIDQKALAAFRA 208 Query: 197 KHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEK-------KFGR 249 + L+P+ P +GT+ P + VW+ E RK AE EK K GR Sbjct: 209 RS--LNPEHPSERGTICGPEY-------VWQMHEKLRKPYQALPAEVEKMMKALGDKTGR 259 Query: 250 KYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVEEIR-E 308 Y+ + D E + + MGS +++++ + E YK G K+ +YRPF VE Sbjct: 260 YYKPYQYAGPRDPENVIIMMGSGCDPVEEFITEHPE--YKTGLIKVYLYRPFSVEMFNAA 317 Query: 309 LAKKTKVLAFIEKDIS-MGLYGAVFTDASAALINE 342 + K + ++K + G +F D +AA+I + Sbjct: 318 IPSSVKRVCVLDKVVDPTGPREPLFEDVAAAIIGQ 352 >pir||S58236 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) - Entamoeba histolytica >gi|929587|emb|CAA90575.1| (Z50193) pyruvate oxidoreductase [Entamoeba histolytica] Length = 1165 Score = 109 bits (271), Expect = 4e-23 Identities = 102/391 (26%), Positives = 181/391 (46%), Gaps = 28/391 (7%) Query: 10 NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDA-----EFIKVESEHSAIS 64 N+AAA+ + A V FPITPS+ + E + + G + + ++ESE A Sbjct: 7 NQAAAYVS-YALSDVSFIFPITPSSPMAENADVWSSQGRKNVFGQVVDVYEMESEAGASG 65 Query: 65 ALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALS-APINIWNDWQD 123 A+ G AAG T T SQGL LM + AG LP V + RAL+ ++I+ D D Sbjct: 66 AVHGGCAAGSLVSTYTCSQGLMLMIPNMIKIAGEHLPCVFHVTARALAEQALSIFGDHSD 125 Query: 124 TISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPD 183 ++ R TG+ + N Q+ DL ++A+ + LP M FD F +H ++ + Sbjct: 126 VMACRSTGFCLLSSHNVQQCHDLAIVAHLATLE--ASLPFMHFFDGFRTSHEIQKIHQLT 183 Query: 184 QEVVDEFLGEYEPKHAY---LDPKRPITQGTLAFPAHYMEARYLVWEAMENAR--KVIDE 238 + + + A+ L+P P +GT P + + + + + +++ + Sbjct: 184 YDQIKSLVDMKYVDRAHKRGLNPIHPSQRGTSQGPDVILPSLLKIKSNADYLKVPEIVQK 243 Query: 239 AFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVD---KKREEGYKVGAAKM 295 + + GR Y+ E Y DAE + V MG+ L++ VD K+ EE KVG + Sbjct: 244 YMDKVGELTGRHYKIFEYYGAADAERVVVVMGAAVPVLEECVDYLMKELEE--KVGVLSV 301 Query: 296 TVYRPFPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLMLDFIA 353 +YRP+ + + +L ++ +++ GL+G ++ D + L++ + + Sbjct: 302 HLYRPWSAKHFLEQLPNTVTKISVLDRTKEAGLFGEPLYLDVATTLLDAGKHIKCVGGRY 361 Query: 354 GLGGRDVTFNQLDEALSIAKEALEKGKVEKP 384 GLG ++ T ++AK + K E+P Sbjct: 362 GLGSKEFT-------PAMAKAVFDNLKNEEP 385 >pir||T43258 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) pfoA precursor, hydrogenosomal - Trichomonas vaginalis >gi|622958|gb|AAA85494.1| (U16822) pyruvate:ferredoxin oxidoreductas proprotein [Trichomonas vaginalis] Length = 1157 Score = 109 bits (270), Expect = 5e-23 Identities = 96/335 (28%), Positives = 154/335 (45%), Gaps = 33/335 (9%) Query: 28 FPITPSTLVPEKISEFVANGELDAEFIKV-----ESEHSAISALVGASAAGVRTFTATAS 82 +PITP+T + E + ++A G + KV +SE A +A+ GA+A G T TAS Sbjct: 31 YPITPATTMGELVDAWIAQGRKNIWGNKVHMAMMQSEGGAAAAVHGATAVGALCATFTAS 90 Query: 83 QGLALMHEVLFIAAGMRLPIVMAIGNRAL-SAPINIWNDWQDTISQRDTGWIQFYAENNQ 141 QG LM ++ G P V I R + ++ ++I+ND D + R TG ++ Q Sbjct: 91 QGALLMIPDMYKIIGEMCPAVFHISARCIATSALSIYNDHGDIYACRATGMPILFSNGVQ 150 Query: 142 EALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEVV-----DEFLGEYEP 196 EA DL +A+ LP + FD F +H + E D E + + L + Sbjct: 151 EAHDLAAVAHLTT--IHTGLPFIHTFDGFRTSHEINTYEELDNETLWPLIDQKALAAFRA 208 Query: 197 KHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEK-------KFGR 249 + L+P+ P +GT+ P + VW+ E RK E EK K GR Sbjct: 209 RS--LNPEHPSERGTICGPEY-------VWQMHEKLRKPFQALPTEVEKMMKALGDKTGR 259 Query: 250 KYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVEEIR-E 308 Y+ + D E + + MGS +++++ + E +K G K+ ++RPF VE Sbjct: 260 YYKPYQYAGPRDPENVIIMMGSGCDPVEEYITEHPE--FKTGLIKVHLFRPFSVEMFNAA 317 Query: 309 LAKKTKVLAFIEKDIS-MGLYGAVFTDASAALINE 342 + K + ++K + G +F D +AALI E Sbjct: 318 IPASVKKICVLDKVVDPTGPREPLFEDVAAALIGE 352 >pir||C75168 2-ketoglutarate ferredoxin oxidoreductase, chain alpha (kora-1) PAB2359 - Pyrococcus abyssi (strain Orsay) >gi|5457936|emb|CAB49426.1| (AJ248284) 2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA-1) [Pyrococcus abyssi] Length = 408 Score = 108 bits (266), Expect = 2e-22 Identities = 102/337 (30%), Positives = 155/337 (45%), Gaps = 26/337 (7%) Query: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAL 66 M +EA A+ A A + A +PITPS+ + E ++ + ++ ++++E E ++I+A+ Sbjct: 37 MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAM 94 Query: 67 VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTIS 126 VGAS G++ TAT+ G +LM E L A P+V+ R+ + Q Sbjct: 95 VGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFF 154 Query: 127 QRDTGW------IQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 Q G + + ++A + A+ VAE R+ P +V FD IL HT E + Sbjct: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAE--RLRTPVVVLFDG-ILGHTREQIR 211 Query: 181 IPDQ---EVVDEFLGEYEPKHAYLDPKRPITQGTLAFP--AHYMEARYLVWEAMENARKV 235 IPD E+V L + E + A L P G P H EN + Sbjct: 212 IPDPDEVEIVYRKLPQNE-EEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRD 270 Query: 236 I--DEAFAEFEKKFGRK-------YQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREE 286 + E + ++ RK Y+K EEY TDDAEI+ V+ G A V K R+E Sbjct: 271 VYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKE 330 Query: 287 GYKVGAAKMTVYRPFPVEEIRELAKKTKVLAFIEKDI 323 G KVG PFP E +REL KK + + E ++ Sbjct: 331 GIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNL 367 >pir||B71047 probable ferredoxin oxidoreductase alpha subunit - Pyrococcus horikoshii >gi|3258095|dbj|BAA30778.1| (AP000006) 408aa long hypothetical ferredoxin oxidoreductase alpha subunit [Pyrococcus horikoshii] Length = 408 Score = 105 bits (259), Expect = 1e-21 Identities = 99/336 (29%), Positives = 148/336 (43%), Gaps = 24/336 (7%) Query: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAL 66 M +EA A+ A A + A +PITPS+ + E ++ + ++ ++++E E +I+A+ Sbjct: 37 MMGDEAIAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIGSIAAM 94 Query: 67 VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTIS 126 +GAS G++ TAT+ G +LM E + A PIV+ R+ + Q Sbjct: 95 IGASWTGLKAMTATSGPGFSLMQENIGYAVMTETPIVVVNVQRSGPSTGQATKGAQGDFF 154 Query: 127 QR------DTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 Q D I + ++A + A+ +AE R P +V FD IL HT E + Sbjct: 155 QARWGTHGDHPMIAVSPISVEDAFWETIRAFNIAEKLRT--PVIVLFDG-ILGHTREQIR 211 Query: 181 IPDQEVVDEFL-----GEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKV 235 IPD + V+ E E K + DP F Y R V Sbjct: 212 IPDPDEVEITYRKLPGSEEEAKLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDV 271 Query: 236 -IDEAFAEFEKKFGRK-------YQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEG 287 E + ++ RK Y+K EEY TDDAEI+ V+ G A V K REEG Sbjct: 272 YTQEVHDKLVRRIHRKIEQNRDVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKAREEG 331 Query: 288 YKVGAAKMTVYRPFPVEEIRELAKKTKVLAFIEKDI 323 K G PFP E +REL KK + + E ++ Sbjct: 332 IKAGLFVPKTVHPFPGERMRELGKKVRAILVPEMNL 367 >pir||T18528 probable pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) - Giardia intestinalis >gi|960283|gb|AAA74894.1| (L27221) pyruvate:ferredoxin oxidoreductase [Giardia intestinalis] Length = 1253 Score = 103 bits (255), Expect = 3e-21 Identities = 87/330 (26%), Positives = 157/330 (47%), Gaps = 18/330 (5%) Query: 26 AAFPITPSTLVPEKISEFVANGELD--AEFIKVE---SEHSAISALVGASAAGVRTFTAT 80 A FPITPS+++ E I ++ A G+ + + V SE AI GA+ AG T T + Sbjct: 31 AIFPITPSSVMAEMIEQYAAQGKKNIFGNVVTVRQAWSELGAIGTCHGAATAGALTATFS 90 Query: 81 ASQGLALMHEVLFIAAGMRLPIVMAIGNRALS-APINIWNDWQDTISQRDTGWIQFYAEN 139 +SQG+ LM L+ AG R+P V+ + R + A ++ D D + T + N Sbjct: 91 SSQGVLLMISNLYHMAGERIPFVLHVATRTVGMAATSLATDHTDVYAIEGTNMCALSSCN 150 Query: 140 NQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEI-PDQEVVDEFLGE----- 193 QE D+ L+A+ A + + F+ + ++H E +++ D + +FL E Sbjct: 151 VQECYDMSLVAHTTATNVQAAFCHF--FEGYRVSHQFETIQVFKDDADIKDFLSEDQLAK 208 Query: 194 YEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEKKFGRKYQK 253 + ++A +D RPI +M+ ++ I+EAF +K GR+Y Sbjct: 209 WRSENA-MDTDRPIASNIGLGGEIHMQIVESQGAVFDSIPYRIEEAFDLLHRKTGRRYHC 267 Query: 254 IEEYRTDDAEIIFVTMGSLAGTLKDWVDK-KREEGYKVGAAKMTVYRPFPVEEI-RELAK 311 E + +++ V MG+ + T ++ VD E +VG ++ ++RPF +E + K Sbjct: 268 FEYFGHPTPDVVVVVMGATSLTFENVVDALVNRENRRVGFVRVRLFRPFSIELFSNAIPK 327 Query: 312 KTKVLAFIEKDIS-MGLYGAVFTDASAALI 340 KV+ +++ + G ++ + AAL+ Sbjct: 328 SAKVVVALDRAPELLNAGGTLYRETLAALM 357 >pir||A69194 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621790|gb|AAB85209.1| (AE000849) 2-oxoisovalerate oxidoreductase, beta subunit [Methanobacterium thermoautotrophicum] Length = 348 Score = 97.9 bits (240), Expect = 2e-19 Identities = 87/311 (27%), Positives = 142/311 (44%), Gaps = 27/311 (8%) Query: 6 VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65 ++K N A A A +PITP++ + + S + + +F++ ESE +AI+ Sbjct: 1 MVKGNTAVIIGAMYAGCDCYFGYPITPASEILHEASRYFPM--VGRKFVQAESEEAAINM 58 Query: 66 LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINI---WNDWQ 122 + GA+AAG R TA++ G++L E + AG LP V+ RA NI D+ Sbjct: 59 VYGAAAAGHRVMTASSGPGISLKQEGISFLAGAELPAVIVDVMRAGPGLGNIGPEQGDYN 118 Query: 123 DTISQRDTGWIQ---FYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPV 179 + G + + QE DL + A+++A+ R P +V DA +L EP+ Sbjct: 119 QIVKGGGHGNYRNMVLAPSSVQEMCDLTMEAFELADKYR--NPVVVLTDA-VLGQMAEPL 175 Query: 180 EIPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEA 239 P++ V E+ P ++ G + + + +L ++ +E + E Sbjct: 176 RFPEEAV------EHRPDTSW------AVCGNRETMKNLVTSIFLDFDELEEFNFYLQEK 223 Query: 240 FAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYR 299 +A E+ R EEY DDAEI+ V G + + V+ R EG VG + Sbjct: 224 YARIEENEVR----YEEYLVDDAEIVMVAYGISSRVARSAVETARAEGINVGLLRPITLF 279 Query: 300 PFPVEEIRELA 310 PFP + IRELA Sbjct: 280 PFPSDRIRELA 290 >sp|O26800|VORB_METTH KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORB (VOR) (2-OXOISOVALERATE OXIDOREDUCTASE BETA CHAIN) (2-OXOISOVALERATE-FERREDOXIN OXIDOREDUCTASE BETA SUBUNIT) Length = 352 Score = 97.9 bits (240), Expect = 2e-19 Identities = 87/311 (27%), Positives = 142/311 (44%), Gaps = 27/311 (8%) Query: 6 VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65 ++K N A A A +PITP++ + + S + + +F++ ESE +AI+ Sbjct: 5 MVKGNTAVIIGAMYAGCDCYFGYPITPASEILHEASRYFPM--VGRKFVQAESEEAAINM 62 Query: 66 LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINI---WNDWQ 122 + GA+AAG R TA++ G++L E + AG LP V+ RA NI D+ Sbjct: 63 VYGAAAAGHRVMTASSGPGISLKQEGISFLAGAELPAVIVDVMRAGPGLGNIGPEQGDYN 122 Query: 123 DTISQRDTGWIQ---FYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPV 179 + G + + QE DL + A+++A+ R P +V DA +L EP+ Sbjct: 123 QIVKGGGHGNYRNMVLAPSSVQEMCDLTMEAFELADKYR--NPVVVLTDA-VLGQMAEPL 179 Query: 180 EIPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEA 239 P++ V E+ P ++ G + + + +L ++ +E + E Sbjct: 180 RFPEEAV------EHRPDTSW------AVCGNRETMKNLVTSIFLDFDELEEFNFYLQEK 227 Query: 240 FAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYR 299 +A E+ R EEY DDAEI+ V G + + V+ R EG VG + Sbjct: 228 YARIEENEVR----YEEYLVDDAEIVMVAYGISSRVARSAVETARAEGINVGLLRPITLF 283 Query: 300 PFPVEEIRELA 310 PFP + IRELA Sbjct: 284 PFPSDRIRELA 294 >pir||H69004 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622136|gb|AAB85529.1| (AE000875) 2-oxoglutarate oxidoreductase, alpha subunit [Methanobacterium thermoautotrophicum] Length = 378 Score = 94.4 bits (231), Expect = 2e-18 Identities = 89/339 (26%), Positives = 148/339 (43%), Gaps = 23/339 (6%) Query: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAL 66 ++ N+A A A A + A +PITPST + E+++ + F+++E E A+ A+ Sbjct: 9 IQGNDACARGAIKAGCRFFAGYPITPSTEIAEEMALLLPRE--GGVFVQMEDEIGALGAV 66 Query: 67 VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTIS 126 +GA +GVR TAT+ G +LM E + AA P+V+ R + Q + Sbjct: 67 IGAVWSGVRGMTATSGPGFSLMQEHVGYAAMTETPLVIVNVQRGSPSTGQPTMASQSDMM 126 Query: 127 QRDTGW------IQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 Q G I + QE D + A+ +AE+ RV P MV D I+ H E + Sbjct: 127 QARWGSHGDYEIIALSPSSVQECFDFTVRAFNLAEEYRV--PVMVMGDE-IVGHMREKIT 183 Query: 181 IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAF 240 IPD+ + + G P +L P G PA R V + D + Sbjct: 184 IPDRVKIRKRRGPSVPPEEFLPFSAP-EDGVPEMPAFGDGYRIPVTGLTHDEGGYPDASN 242 Query: 241 AEFEKKFGRKY-----------QKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYK 289 E + ++ ++E T+DA I ++ G+ + ++ V RE+G + Sbjct: 243 PEGHHRLVKRLCDKILRHRDRISDVQEELTEDAYITVISYGAPSRSVATAVKMAREDGVR 302 Query: 290 VGAAKMTVYRPFPVEEIRELAKKTKVLAFIEKDISMGLY 328 G K+ PFP E+R A+++ L +E ++ Y Sbjct: 303 AGYLKINTPWPFPETEVRAAAERSGKLLVVEMNLGQMFY 341 >sp|O27112|KORA_METTH 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KETOGLUTARATE OXIDOREDUCTASE ALPHA CHAIN) (KOR) (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) Length = 376 Score = 94.4 bits (231), Expect = 2e-18 Identities = 89/339 (26%), Positives = 148/339 (43%), Gaps = 23/339 (6%) Query: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAL 66 ++ N+A A A A + A +PITPST + E+++ + F+++E E A+ A+ Sbjct: 7 IQGNDACARGAIKAGCRFFAGYPITPSTEIAEEMALLLPRE--GGVFVQMEDEIGALGAV 64 Query: 67 VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTIS 126 +GA +GVR TAT+ G +LM E + AA P+V+ R + Q + Sbjct: 65 IGAVWSGVRGMTATSGPGFSLMQEHVGYAAMTETPLVIVNVQRGSPSTGQPTMASQSDMM 124 Query: 127 QRDTGW------IQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180 Q G I + QE D + A+ +AE+ RV P MV D I+ H E + Sbjct: 125 QARWGSHGDYEIIALSPSSVQECFDFTVRAFNLAEEYRV--PVMVMGDE-IVGHMREKIT 181 Query: 181 IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAF 240 IPD+ + + G P +L P G PA R V + D + Sbjct: 182 IPDRVKIRKRRGPSVPPEEFLPFSAP-EDGVPEMPAFGDGYRIPVTGLTHDEGGYPDASN 240 Query: 241 AEFEKKFGRKY-----------QKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYK 289 E + ++ ++E T+DA I ++ G+ + ++ V RE+G + Sbjct: 241 PEGHHRLVKRLCDKILRHRDRISDVQEELTEDAYITVISYGAPSRSVATAVKMAREDGVR 300 Query: 290 VGAAKMTVYRPFPVEEIRELAKKTKVLAFIEKDISMGLY 328 G K+ PFP E+R A+++ L +E ++ Y Sbjct: 301 AGYLKINTPWPFPETEVRAAAERSGKLLVVEMNLGQMFY 339 >gb|AAD55757.1|AF146519_1 (AF146519) putative pyruvate:ferredoxin oxidoreductase 2 [Giardia intestinalis] Length = 512 Score = 90.5 bits (221), Expect = 3e-17 Identities = 69/244 (28%), Positives = 118/244 (48%), Gaps = 8/244 (3%) Query: 70 SAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWNDWQDTISQR 128 S G+ T TASQGL LM ++ AG LP V + R ++ +++ D D ++ R Sbjct: 15 SDTGLLASTYTASQGLLLMIPNMYKMAGEHLPAVFHVAARTIATHSLSVHGDHADIMAVR 74 Query: 129 DTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEVVD 188 TG +E+ QEA+D+ + A+ A P + FD F +HT++ VE+ D E + Sbjct: 75 QTGCTIMVSEDIQEAMDMAIAAHLTAIYSSY--PVVHAFDGFRTSHTIKKVELIDYEHLR 132 Query: 189 EFLGEYEPKHAY----LDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFE 244 + Y+ A+ L P+ P +G+ P +M+A + ++ AF + Sbjct: 133 PHV-PYDEIEAFRQKSLSPQHPEMRGSCQGPPIWMQAGEADNKHYAEIPGHVERAFEKVR 191 Query: 245 KKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVE 304 + GR Y+ + DA + + MGS T+ + V+ E G KVG + ++RPF + Sbjct: 192 EITGRSYKFFNYFGAPDATAVVIIMGSGYLTVHEVVEYLVERGDKVGVVCVHLFRPFCGD 251 Query: 305 EIRE 308 ++ E Sbjct: 252 KLLE 255 >pir||F75168 2-ketoglutarate ferredoxin oxidoreductase, chain alpha (kora-2) PAB0346 - Pyrococcus abyssi (strain Orsay) >gi|5457939|emb|CAB49429.1| (AJ248284) 2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA-2) [Pyrococcus abyssi] Length = 385 Score = 89.3 bits (218), Expect = 7e-17 Identities = 94/331 (28%), Positives = 148/331 (44%), Gaps = 32/331 (9%) Query: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAL 66 ++ +EA A AA LA + A +PITP++ + E ++ ++ +D I++E E ++I+A+ Sbjct: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL--VDGVVIQMEDEIASIAAI 70 Query: 67 VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVM--------AIGNRALSAPINIW 118 +GAS AG + TAT+ G +LM E + A PIV+ + G L + +I Sbjct: 71 IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130 Query: 119 NDWQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEP 178 T D I QEA D + A+ +AE R P ++ DA + H E Sbjct: 131 QSIWGT--HGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRT--PVILLSDAEV-GHMRER 185 Query: 179 VEIPDQ---EVVDEFL--GEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMEN-- 231 V IP+ E+V+ L E E K + DP F Y Y+ + Sbjct: 186 VYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGY--RTYVTGLTHDERG 243 Query: 232 -----ARKVIDEAFAEFEKKFGRKYQKIEEYRT---DDAEIIFVTMGSLAGTLKDWVDKK 283 R+V + +K R + I +Y DDAE+ VT G +A + + + Sbjct: 244 RPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKEL 303 Query: 284 REEGYKVGAAKMTVYRPFPVEEIRELAKKTK 314 RE G K G K+ PF E I ++A K + Sbjct: 304 RELGIKAGLLKINTIWPFDFELIEKIAGKVE 334 >pir||F71046 probable ferredoxin oxidoreductase alpha subunit - Pyrococcus horikoshii >gi|3258091|dbj|BAA30774.1| (AP000006) 385aa long hypothetical ferredoxin oxidoreductase alpha subunit [Pyrococcus horikoshii] Length = 385 Score = 87.4 bits (213), Expect = 3e-16 Identities = 95/329 (28%), Positives = 145/329 (43%), Gaps = 28/329 (8%) Query: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAL 66 ++ +EA A AA LA + A +PITP++ + E ++ ++ +D I++E E +I+A+ Sbjct: 13 IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL--IDGVVIQMEDEIGSIAAV 70 Query: 67 VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVM--------AIGNRALSAPINIW 118 +GAS AGV+ TAT+ G +LM E + A PIV+ + G L + +I Sbjct: 71 IGASWAGVKAMTATSGPGFSLMQENIGYAVMTETPIVVVNVQRGGPSTGQPTLPSQGDIM 130 Query: 119 NDWQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEP 178 T D I QEA D + A+ +AE R P ++ DA + H E Sbjct: 131 QSIWGT--HGDHTLIVLSPSTVQEAFDFTIRAFNLAEKYRT--PVILLSDAEV-GHMRER 185 Query: 179 VEIPDQ---EVVDEFL--GEYEPKHAYLDPKRPITQGTLAFPAHYME-ARYLVWEAMENA 232 V IP+ E+V+ L E E K + DP F Y L + Sbjct: 186 VYIPEPDEIEIVNRKLPGSEEEAKLPFGDPHGDGVPPMPIFGKGYRTYVTGLTHDEKGRP 245 Query: 233 RKVIDEAFAEFEKKFGRKYQK-------IEEYRTDDAEIIFVTMGSLAGTLKDWVDKKRE 285 R V E ++ K +K E DDAEI VT G +A + + + R Sbjct: 246 RTVEREVHERLIRRIFEKIEKNKKDIFDYEARELDDAEIAIVTTGIVARSALRAIKELRN 305 Query: 286 EGYKVGAAKMTVYRPFPVEEIRELAKKTK 314 G K G K+ PF E I ++A+K + Sbjct: 306 LGIKAGLLKINTIWPFDFELIEKVAEKVE 334 >sp|Q57724|KORA_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KETOGLUTARATE OXIDOREDUCTASE ALPHA CHAIN) (KOR) (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT) >gi|2127893|pir||E64334 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain - Methanococcus jannaschii >gi|1592279|gb|AAB98264.1| (U67483) 2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA) [Methanococcus jannaschii] Length = 366 Score = 85.0 bits (207), Expect = 1e-15 Identities = 95/366 (25%), Positives = 168/366 (44%), Gaps = 37/366 (10%) Query: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAL 66 M+ N+A A A A + A +PITPST + E ++ + ++ +I++E E +I+A+ Sbjct: 6 MQGNQACAKGAIKAGCRFFAGYPITPSTEIAEAMARELP--KVGGYYIQMEDEIGSIAAV 63 Query: 67 VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVM--------AIGNRALSAPINIW 118 +GAS G++ TAT+ G +LM E + A P V+ + G +++ ++ Sbjct: 64 IGASWGGLKAMTATSGPGFSLMQENIGFAYMTETPCVVVDIQRGGPSTGQPTMASQGDMM 123 Query: 119 N-DWQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVE 177 W S D I + QE D ++A+ AE R+ P V D I+ H E Sbjct: 124 QCRWG---SHGDYEVIALAPSSVQEMYDFTIMAFNYAEKYRI--PVFVMADE-IVGHMRE 177 Query: 178 PVEIPDQ-EVVDEFLGEYEP-KHAY----LDPKRPITQGTLAFPAHYMEARYLVWEAMEN 231 V + D E+++ E +P K Y L P+ P+ + H + + Sbjct: 178 KVILHDNIEIINRKKPEEKPCKKPYPFDKLIPEMPVFGE--GYNVHITGLTHDERGYPDV 235 Query: 232 ARKVIDEAFAEFEKKFGRKYQKIEEYRTD--DAEIIFVTMGSLAGTLKDWVDKKREEGYK 289 + + D+ K + +I ++ + DAEI+FV GS + T+K V RE+G Sbjct: 236 SPETHDKLVRRIVNKIRKNKDEIIKWEGENLDAEIVFVCYGSPSRTVKHAVRNLREKGLD 295 Query: 290 VGAAKMTVYRPFPVEEIRELAKKTKVLAFIEKDISMG-LYGAVFTDASAALINESEKPLM 348 VG ++ PFP +L KK K + ++++G +Y V + ++E+ ++ Sbjct: 296 VGYIRLITVYPFP----DDLLKKLKAKKVVVPEMNLGQIYYEV-----ERVCKKAEEVIL 346 Query: 349 LDFIAG 354 +D I G Sbjct: 347 VDKIGG 352 >emb|CAA34396.1| (X16345) nifJ [Klebsiella pneumoniae] Length = 167 Score = 80.4 bits (195), Expect = 3e-14 Identities = 56/150 (37%), Positives = 81/150 (53%), Gaps = 8/150 (5%) Query: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELD-----AEFIKVESEHS 61 M N AAAW + A +V A +PITPST + E + E+ A G+ + ++++SE Sbjct: 8 MDGNAAAAWIS-YAFTEVAAIYPITPSTPMAENVDEWAAQGKKNLFGQPVRLMEMQSEAG 66 Query: 62 AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWND 120 A A+ GA AG T T TASQGL LM ++ AG LP V + RAL+ +NI+ D Sbjct: 67 AAGAVHGALQAGALTTTYTASQGLLLMIPNMYKIAGELLPGVFHVSARALATNSLNIFGD 126 Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLA 150 D ++ R +G N Q+ +DL +A Sbjct: 127 -HDVMAVRQSGCAMLAENNVQQVMDLSTIA 155 >pir||E64593 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain - Helicobacter pylori (strain 26695) >gi|2313707|gb|AAD07654.1| (AE000572) ferredoxin oxidoreductase, alpha subunit [Helicobacter pylori 26695] Length = 375 Score = 72.2 bits (174), Expect = 1e-11 Identities = 85/341 (24%), Positives = 146/341 (41%), Gaps = 37/341 (10%) Query: 6 VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65 + NE A AA + +PITPS+ + +S VA + FI++E E S IS Sbjct: 5 ISDGNELVAKAAIEVGCRFFGGYPITPSSDIMHAMS--VALPKCGGHFIQMEDEISGISV 62 Query: 66 LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125 +GAS +G ++ TA++ G++L E + + +P+V+A R S P + Sbjct: 63 SLGASMSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMR--SGPS---TGMPTRV 117 Query: 126 SQRDTGWIQ-----------FYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTH 174 +Q D +++ N +EA + A+ +A E ++ P + D + H Sbjct: 118 AQGDVNFLRHPIHGDFKAVALAPANLEEAYTETVRAFNLA--EMLMTPVFLLMDETV-GH 174 Query: 175 TVEPVEIPDQEVVD-------EFLG---EYEPKHAYLDPKRPITQGTLAFPAHYMEARY- 223 V+IPD E V EFLG +Y+P D + + H + Sbjct: 175 MYGKVQIPDLEEVQKMTINRKEFLGDKKDYKPYGVAQDEPAVLNPFFKGYRYHVSGLHHG 234 Query: 224 ---LVWEAMENARKVIDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWV 280 E + +ID F + E K + EE + AEI+ + GS++ +K+ + Sbjct: 235 PIGFPTEDAKIGGDLIDRLFNKIESK-QDIINENEEMDLEGAEIVVIAYGSVSLAVKEAL 293 Query: 281 -DKKREEGYKVGAAKMTVYRPFPVEEIRELAKKTKVLAFIE 320 D +E KVG + P P + ++E+ K + + IE Sbjct: 294 KDYHKESKQKVGFFRPKTLWPSPAKRLKEIGDKYEKILVIE 334 >gb|AAC38211.1| (AF021094) OorA subunit of 2-oxoglutarate:acceptor oxidoreductase [Helicobacter pylori] Length = 371 Score = 71.0 bits (171), Expect = 2e-11 Identities = 84/338 (24%), Positives = 143/338 (41%), Gaps = 31/338 (9%) Query: 6 VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65 + NE A AA + +PITPS+ + +S VA FI++E E S IS Sbjct: 5 ISDGNELVAKAAIEVGCRFFGGYPITPSSDIMHAMS--VALPNCGGHFIQMEDEISGISV 62 Query: 66 LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125 +GAS +G ++ TA++ G++L E + + +P+V+A R S P + Sbjct: 63 SLGASMSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMR--SGPS---TGMPTRV 117 Query: 126 SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVL---LPAMVGFDAFILT-----HTVE 177 Q D +++ + +A+ L + + A E L M+ F+L H Sbjct: 118 DQGDVNFLRHPIHGDFKAVALAPASLEEAYTETARAFNLAEMLMTPVFLLMDETVGHMYG 177 Query: 178 PVEIPDQEVVD-------EFLG---EYEPKHAYLDPKRPITQGTLAFPAHYMEARY---- 223 V+IPD E V EF+G +Y+P D + + H + Sbjct: 178 KVQIPDLEEVQKTTINRKEFVGDKKDYKPYGVAQDEPAVLNPFFKGYRYHVSGLHHGPIG 237 Query: 224 LVWEAMENARKVIDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWV-DK 282 E + +ID F + E K + EE + AEI+ + GS++ +K+ + D Sbjct: 238 FPTEDAKIGGDLIDRLFNKIESK-QDIINENEEMDLEGAEIVIIAYGSVSLAVKEALKDY 296 Query: 283 KREEGYKVGAAKMTVYRPFPVEEIRELAKKTKVLAFIE 320 +E KVG + P P + ++E+ K + + IE Sbjct: 297 HKESNQKVGFFRPKTLWPSPAKRLKEIGDKYEKILVIE 334 >emb|CAA25502.1| (X01007) URF [Klebsiella pneumoniae] Length = 127 Score = 70.6 bits (170), Expect = 3e-11 Identities = 48/120 (40%), Positives = 67/120 (55%), Gaps = 7/120 (5%) Query: 7 MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELD-----AEFIKVESEHS 61 M N AAAW + A +V A +PITPST + E + E+ A G+ + ++++SE Sbjct: 8 MDGNAAAAWIS-YAFTEVAAIYPITPSTPMAENVDEWAAQGKKNLFGQPVRLMEMQSEAG 66 Query: 62 AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWND 120 A A+ GA AG T T TASQGL LM ++ AG LP V + RAL+ +NI+ D Sbjct: 67 AAGAVHGALQAGALTTTYTASQGLLLMIPNMYKIAGELLPGVFHVSARALATNSLNIFGD 126 >pir||G71919 chain of 2-oxoglutarate oxidoreductase - Helicobacter pylori (strain J99) >gi|4155084|gb|AAD06119.1| (AE001486) SUBUNIT OF 2-OXOGLUTARATE OXIDOREDUCTASE [Helicobacter pylori J99] Length = 375 Score = 69.5 bits (167), Expect = 6e-11 Identities = 83/341 (24%), Positives = 144/341 (41%), Gaps = 37/341 (10%) Query: 6 VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65 + NE A AA + +PITPS+ + +S VA + FI++E E S IS Sbjct: 5 ISDGNELVAKAAIEVGCRFFGGYPITPSSDIMHAMS--VALPKCGGHFIQMEDEISGISV 62 Query: 66 LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125 +GAS +G ++ TA++ G++L E + + +P+V+A R S P + Sbjct: 63 SLGASMSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMR--SGPS---TGMPTRV 117 Query: 126 SQRDTGWIQ-----------FYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTH 174 +Q D +++ N +EA + A+ +A E ++ P + D + H Sbjct: 118 AQGDVNFLRHPIHGDFKAVALAPANLEEAYTETVRAFNLA--EMLMTPVFLLMDETV-GH 174 Query: 175 TVEPVEIPDQEVVD-------EFLG---EYEPKHAYLDPKRPITQGTLAFPAHYMEARY- 223 V+IPD E V EF G +Y+P D + + H + Sbjct: 175 MYGKVQIPDLEEVQKMTINRKEFAGDKKDYKPYGVAQDEPAVLNPFFKGYRYHVSGLHHG 234 Query: 224 ---LVWEAMENARKVIDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWV 280 E + +ID F + E K + EE + EI+ + GS++ +K+ + Sbjct: 235 PIGFPTEDAKIGGDLIDRLFHKIESK-QDIINENEEMDLEGTEIVIIAYGSVSLAVKEAL 293 Query: 281 -DKKREEGYKVGAAKMTVYRPFPVEEIRELAKKTKVLAFIE 320 D +E KVG + P P + ++E+ K + + IE Sbjct: 294 KDYNKESKQKVGFFRPKTLWPSPAKRLKEIGDKYEKILVIE 334 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.319 0.135 0.387 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 138190127 Number of Sequences: 2977 Number of extensions: 5664194 Number of successful extensions: 16900 Number of sequences better than 1.0e-10: 69 Number of HSP's better than 0.0 without gapping: 28 Number of HSP's successfully gapped in prelim test: 41 Number of HSP's that attempted gapping in prelim test: 16697 Number of HSP's gapped (non-prelim): 75 length of query: 395 length of database: 189,106,746 effective HSP length: 58 effective length of query: 337 effective length of database: 154,394,500 effective search space: 52030946500 effective search space used: 52030946500 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.7 bits) S2: 166 (69.1 bits)