BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1475 (porA) DE:PYRUVATE SYNTHASE SUBUNIT PORA (EC 1.2.7.1)
(PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR)
         (395 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||G75046 pyruvate synthase (EC 1.2.7.1) alpha chain PAB1475 -...   786  0.0
pir||E71114 probable ferredoxin oxidoreductase alpha-2 subunit -...   755  0.0
sp|O73986|PORA_PYRHO PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX...   755  0.0
sp|Q51804|PORA_PYRFU PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX...   727  0.0
gb|AAF91264.1|AF230199_6 (AF230199) pyruvate oxidoreductase alph...   430  e-119
sp|P56810|PORA_METTH PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX...   414  e-114
sp|Q57715|PORA_METJA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX...   411  e-114
sp|Q51801|VORA_PYRFU KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA...   392  e-108
pir||A71114 probable ferredoxin oxidoreductase alpha subunit - P...   388  e-107
sp|O58413|VORA_PYRHO KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA...   388  e-107
pir||B75047 probable 2-oxoisovalerate--ferredoxin oxidoreductase...   383  e-105
emb|CAA59457.1| (X85171) alpha subunit of pyruvate ferredoxin ox...   340  2e-92
sp|O05651|PORA_THEMA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OX...   340  2e-92
emb|CAC11767.1| (AL445064) probable 2-ketovalerate ferredoxin ox...   326  3e-88
gi|11499291 pyruvate ferredoxin oxidoreductase, subunit alpha (p...   322  5e-87
gb|AAK41454.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin...   308  6e-83
gb|AAK42867.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin...   282  5e-75
pir||H71857 pyruvate ferrodoxin oxidoreductase - Helicobacter py...   277  2e-73
pir||F64658 pyruvate synthase (EC 1.2.7.1) alpha chain - Helicob...   275  6e-73
gb|AAC02293.1| (AF013980) pyruvate:ferredoxin oxidoreductase alp...   273  2e-72
gb|AAK42308.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin...   264  2e-69
pir||S74041 pyruvate synthase (EC 1.2.7.1) alpha chain - Sulfolo...   264  2e-69
gi|11499635 2-ketoisovalerate ferredoxin oxidoreductase, subunit...   243  3e-63
gb|AAC38206.1| (AF021092) PorA subunit of pyruvate:flavodoxin ox...   230  2e-59
emb|CAB43933.1| (Y17726) pyruvate ferredoxin oxidoreductase [Clo...   165  9e-40
gb|AAD55756.1|AF132673_1 (AF132673) pyruvate:ferredoxin oxidored...   162  5e-39
emb|CAB43935.1| (Y17727) pyruvate ferredoxin oxidoreductase [Clo...   159  7e-38
pir||A81294 pyruvate-flavodoxin oxidoreductase Cj1476c [imported...   151  2e-35
sp|P19543|NIFJ_ENTAG PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|4690...   150  3e-35
sp|P03833|NIFJ_KLEPN PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|4382...   148  1e-34
pir||QQKBFP pyruvate (flavodoxin) dehydrogenase nifJ (EC 1.2.99....   148  1e-34
pir||G71262 probable pyruvate (flavodoxin) dehydrogenase (EC 1.2...   145  7e-34
gb|AAC83148.1| (AF061850) putative pyruvate oxidoreductase; POR ...   143  3e-33
emb|CAA70873.1| (Y09702) pyruvate-ferredoxin oxidoreductase [Des...   138  9e-32
pdb|1B0P|A Chain A, Crystal Structure Of Pyruvate-Ferredoxin Oxi...   138  9e-32
emb|CAA57480.1| (X81893) nifJ [Enterobacter agglomerans]              138  1e-31
pir||C70403 ferredoxin oxidoreductase alpha subunit - Aquifex ae...   138  1e-31
dbj|BAA95605.1| (AB042412) pyruvate:ferredoxin oxidoreductase al...   138  1e-31
sp|P52647|NIFJ_ECOLI PROBABLE PYRUVATE-FLAVODOXIN OXIDOREDUCTASE...   134  1e-30
sp|P52965|NIFJ_SYNY3 PUTATIVE PYRUVATE-FLAVODOXIN OXIDOREDUCTASE...   134  2e-30
emb|CAB43934.1| (Y17727) pyruvate ferredoxin oxidoreductase [Clo...   133  3e-30
pir||F82447 pyruvate-flavoredoxin oxidoreductase VCA0530 [import...   130  3e-29
pir||B70400 ferredoxin oxidoreductase alpha subunit - Aquifex ae...   129  4e-29
sp|Q06879|NIFJ_ANASP PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|2126...   123  2e-27
gb|AAD55754.1|AF132546_1 (AF132546) pyruvate:ferredoxin oxidored...   119  5e-26
dbj|BAB12024.1| (AB021127) pyruvate:NADP+ oxidoreductase [Euglen...   115  7e-25
gb|AAB49653.1| (U30149) pyruvate:ferredoxin oxidoreductase [Enta...   115  9e-25
sp|Q53046|NIFJ_RHORU PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|6288...   113  4e-24
pir||S70963 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) - ...   113  4e-24
pir||H72214 hypothetical protein TM1759 - Thermotoga maritima (s...   112  8e-24
pir||T43259 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) pf...   111  1e-23
pir||S58236 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) - ...   109  4e-23
pir||T43258 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) pf...   109  5e-23
pir||C75168 2-ketoglutarate ferredoxin oxidoreductase, chain alp...   108  2e-22
pir||B71047 probable ferredoxin oxidoreductase alpha subunit - P...   105  1e-21
pir||T18528 probable pyruvate (flavodoxin) dehydrogenase (EC 1.2...   103  3e-21
pir||A69194 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al...    98  2e-19
sp|O26800|VORB_METTH KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORB...    98  2e-19
pir||H69004 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7....    94  2e-18
sp|O27112|KORA_METTH 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KET...    94  2e-18
gb|AAD55757.1|AF146519_1 (AF146519) putative pyruvate:ferredoxin...    90  3e-17
pir||F75168 2-ketoglutarate ferredoxin oxidoreductase, chain alp...    89  7e-17
pir||F71046 probable ferredoxin oxidoreductase alpha subunit - P...    87  3e-16
sp|Q57724|KORA_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KET...    85  1e-15
emb|CAA34396.1| (X16345) nifJ [Klebsiella pneumoniae]                  80  3e-14
pir||E64593 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) al...    72  1e-11
gb|AAC38211.1| (AF021094) OorA subunit of 2-oxoglutarate:accepto...    71  2e-11
emb|CAA25502.1| (X01007) URF [Klebsiella pneumoniae]                   71  3e-11
pir||G71919 chain of 2-oxoglutarate oxidoreductase - Helicobacte...    69  6e-11

>pir||G75046 pyruvate synthase (EC 1.2.7.1) alpha chain PAB1475 - Pyrococcus
           abyssi (strain Orsay) >gi|5458781|emb|CAB50268.1|
           (AJ248287) PYRUVATE SYNTHASE SUBUNIT PORA (EC 1.2.7.1)
           (PYRUVATE OXIDOREDUCTASE ALPHA CHAIN) (POR) [Pyrococcus
           abyssi]
           Length = 395
           
 Score =  786 bits (2007), Expect = 0.0
 Identities = 395/395 (100%), Positives = 395/395 (100%)

Query: 1   MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEH 60
           MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEH
Sbjct: 1   MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEH 60

Query: 61  SAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWND 120
           SAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWND
Sbjct: 61  SAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWND 120

Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180
           WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE
Sbjct: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180

Query: 181 IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAF 240
           IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAF
Sbjct: 181 IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAF 240

Query: 241 AEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300
           AEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP
Sbjct: 241 AEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300

Query: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV 360
           FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV
Sbjct: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV 360

Query: 361 TFNQLDEALSIAKEALEKGKVEKPIHWIGLRKELL 395
           TFNQLDEALSIAKEALEKGKVEKPIHWIGLRKELL
Sbjct: 361 TFNQLDEALSIAKEALEKGKVEKPIHWIGLRKELL 395


>pir||E71114 probable ferredoxin oxidoreductase alpha-2 subunit - Pyrococcus
           horikoshii >gi|3257092|dbj|BAA29775.1| (AP000003) 398aa
           long hypothetical ferredoxin oxidoreductase alpha-2
           subunit [Pyrococcus horikoshii]
           Length = 398
           
 Score =  755 bits (1928), Expect = 0.0
 Identities = 375/395 (94%), Positives = 388/395 (97%)

Query: 1   MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEH 60
           MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEH
Sbjct: 4   MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEH 63

Query: 61  SAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWND 120
           SAISA+VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNR+LSAPINIWND
Sbjct: 64  SAISAVVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRSLSAPINIWND 123

Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180
           WQD+ISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE
Sbjct: 124 WQDSISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 183

Query: 181 IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAF 240
           IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEA+YLVW+AME ARKVIDEAF
Sbjct: 184 IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEAKYLVWDAMEKARKVIDEAF 243

Query: 241 AEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300
           AEFEK+FGRKYQKIEEY+TDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP
Sbjct: 244 AEFEKRFGRKYQKIEEYKTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 303

Query: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV 360
           FPVEEIR LAKK KVL FIEKDIS+GLYGAVF DASAAL+NESE+PLMLDFIAGLGGRDV
Sbjct: 304 FPVEEIRALAKKAKVLGFIEKDISIGLYGAVFIDASAALVNESERPLMLDFIAGLGGRDV 363

Query: 361 TFNQLDEALSIAKEALEKGKVEKPIHWIGLRKELL 395
           TF QLD+AL IA+EALEKG+VEKPIHWIGLRKELL
Sbjct: 364 TFGQLDDALRIAEEALEKGEVEKPIHWIGLRKELL 398


>sp|O73986|PORA_PYRHO PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
           CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
           SUBUNIT)
           Length = 395
           
 Score =  755 bits (1928), Expect = 0.0
 Identities = 375/395 (94%), Positives = 388/395 (97%)

Query: 1   MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEH 60
           MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEH
Sbjct: 1   MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEH 60

Query: 61  SAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWND 120
           SAISA+VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNR+LSAPINIWND
Sbjct: 61  SAISAVVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRSLSAPINIWND 120

Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180
           WQD+ISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE
Sbjct: 121 WQDSISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180

Query: 181 IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAF 240
           IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEA+YLVW+AME ARKVIDEAF
Sbjct: 181 IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEAKYLVWDAMEKARKVIDEAF 240

Query: 241 AEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300
           AEFEK+FGRKYQKIEEY+TDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP
Sbjct: 241 AEFEKRFGRKYQKIEEYKTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300

Query: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV 360
           FPVEEIR LAKK KVL FIEKDIS+GLYGAVF DASAAL+NESE+PLMLDFIAGLGGRDV
Sbjct: 301 FPVEEIRALAKKAKVLGFIEKDISIGLYGAVFIDASAALVNESERPLMLDFIAGLGGRDV 360

Query: 361 TFNQLDEALSIAKEALEKGKVEKPIHWIGLRKELL 395
           TF QLD+AL IA+EALEKG+VEKPIHWIGLRKELL
Sbjct: 361 TFGQLDDALRIAEEALEKGEVEKPIHWIGLRKELL 395


>sp|Q51804|PORA_PYRFU PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
           CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
           SUBUNIT) >gi|11280155|pir||T45088 pyruvate synthase (EC
           1.2.7.1) alpha-2 chain [imported] - Pyrococcus furiosus
           >gi|1197363|emb|CAA59505.1| (X85250) pyruvate ferredoxin
           oxidoreductase alpha-2 [Pyrococcus furiosus]
           Length = 396
           
 Score =  727 bits (1857), Expect = 0.0
 Identities = 357/395 (90%), Positives = 383/395 (96%)

Query: 1   MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEH 60
           MPIR VMKANEAAAWAAKLAKPKVIAAFPITPSTL+PEKISEFVANGELDAEFIKVESEH
Sbjct: 1   MPIRKVMKANEAAAWAAKLAKPKVIAAFPITPSTLIPEKISEFVANGELDAEFIKVESEH 60

Query: 61  SAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWND 120
           SAISA VGA+AAGVRTFTATASQGLALMHE+LFIAAGMRLPIVMAIGNRALSAPINIWND
Sbjct: 61  SAISACVGAAAAGVRTFTATASQGLALMHEILFIAAGMRLPIVMAIGNRALSAPINIWND 120

Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180
           WQDTISQRDTGW+QFYAENNQEALDLIL+AYKVAEDERVLLPAMVGFDAFILTHTVEPVE
Sbjct: 121 WQDTISQRDTGWMQFYAENNQEALDLILIAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180

Query: 181 IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAF 240
           IPDQEVVDEFLGEYEPKHAY+DP RPITQG+LAFPAHYME+RY VWEAME A+KVIDEAF
Sbjct: 181 IPDQEVVDEFLGEYEPKHAYIDPARPITQGSLAFPAHYMESRYTVWEAMERAKKVIDEAF 240

Query: 241 AEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300
           AEFEKKFGRKYQKIEEY+T+DA+IIFVTMGSLAGTL +W+DKKREEGYKVGAAK+TVYRP
Sbjct: 241 AEFEKKFGRKYQKIEEYKTEDADIIFVTMGSLAGTLNEWIDKKREEGYKVGAAKITVYRP 300

Query: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV 360
           FPVEEIRELAKK KVLAF+EK+I++GLYGAVFTDASAALINESEKPLM+DFI G GGRDV
Sbjct: 301 FPVEEIRELAKKAKVLAFLEKNITIGLYGAVFTDASAALINESEKPLMVDFIVGHGGRDV 360

Query: 361 TFNQLDEALSIAKEALEKGKVEKPIHWIGLRKELL 395
           TFNQLDEAL IA++AL++GKVE PI+WIGLR EL+
Sbjct: 361 TFNQLDEALEIAEKALKEGKVENPINWIGLRWELV 395


>gb|AAF91264.1|AF230199_6 (AF230199) pyruvate oxidoreductase alpha subunit [Methanococcus
           maripaludis]
           Length = 387
           
 Score =  430 bits (1093), Expect = e-119
 Identities = 223/393 (56%), Positives = 286/393 (72%), Gaps = 16/393 (4%)

Query: 6   VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65
           V+    AAA AAKLA   VIAA+PITP T   EK+++FVANGEL+AE+IKVESEHSA+SA
Sbjct: 6   VITGTSAAAEAAKLADVDVIAAYPITPQTTCVEKLADFVANGELNAEYIKVESEHSAMSA 65

Query: 66  LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125
            +GASAAG R FTAT+SQGLALMHEVLF AAGMR+P+VM   NRALSAPINIWND QD++
Sbjct: 66  SIGASAAGARAFTATSSQGLALMHEVLFAAAGMRVPVVMMNANRALSAPINIWNDQQDSL 125

Query: 126 SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQE 185
           SQRDTGWIQ YAE+NQE LDL++ A+K+AEDE+VLLP MV  D FILTHTVEPV +P QE
Sbjct: 126 SQRDTGWIQLYAEDNQEVLDLVIQAFKIAEDEKVLLPVMVNLDGFILTHTVEPVTLPKQE 185

Query: 186 VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEK 245
            V +F+G YEPKHAYLDPK+P+TQG L  P +YME RY +  AMENA+KVI +    F +
Sbjct: 186 NVLDFIGTYEPKHAYLDPKKPMTQGALGDPNYYMETRYAIETAMENAKKVIADVHDAFAE 245

Query: 246 KFGRKYQK--IEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPV 303
           KF R Y    IE Y  + AE + V MGS+ GT+KD +D K++EG ++G  K+  YRP P+
Sbjct: 246 KFNRAYGNGLIESYNLEKAENVIVAMGSICGTIKDMIDLKKKEGVEIGLLKIRCYRPLPI 305

Query: 304 EEIRELAKKTKVLAFIEKDISMGL-YGAVFTDASAALINESEKPLMLDFIAGLGGRDVTF 362
           E I++  K  K +A ++K IS+G+  GA++ D ++ L ++      +++I GLGGRD+T 
Sbjct: 306 EMIKDALKNAKNVAILDKSISLGMNKGAIYADVASHLKDKK----TVNYIVGLGGRDIT- 360

Query: 363 NQLDEALSIAK--EALEKGKVEKPIHWIGLRKE 393
              ++ L I    E  E GK     +WIGL++E
Sbjct: 361 --PEDILGIYDDVEISEDGKT----NWIGLKEE 387


>sp|P56810|PORA_METTH PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
           CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
           SUBUNIT) >gi|7449945|pir||E69099 pyruvate synthase (EC
           1.2.7.1) alpha chain - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622870|gb|AAB86209.1| (AE000929) pyruvate
           oxidoreductase, alpha subunit  [Methanobacterium
           thermoautotrophicum]
           Length = 383
           
 Score =  414 bits (1052), Expect = e-114
 Identities = 209/388 (53%), Positives = 284/388 (72%), Gaps = 11/388 (2%)

Query: 6   VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65
           V+ AN+A A AAKLAKPKVI  +PITP T + E +++FVA+GEL AE+I+VESEHSA+SA
Sbjct: 5   VISANQAVAEAAKLAKPKVIPVYPITPQTSISEYLAKFVADGELKAEYIRVESEHSAMSA 64

Query: 66  LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125
            VGAS AGVR FTAT+SQGLALMHE+++ AAG+R PIVMA  NRALSAP++IWND QD+I
Sbjct: 65  CVGASGAGVRVFTATSSQGLALMHEIVYAAAGLRNPIVMANANRALSAPLSIWNDQQDSI 124

Query: 126 SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQE 185
           ++RD+GW+Q Y E+ QEALD +LL+Y+V+ED  VLLP+MV  D FILTHTVEPV+IP QE
Sbjct: 125 AERDSGWMQIYVESGQEALDSVLLSYRVSEDRDVLLPSMVCLDGFILTHTVEPVDIPSQE 184

Query: 186 VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEK 245
            VD FL E++P+   LDP  P++ GT   P +YMEARY V +AME +RK+I+ A  EF +
Sbjct: 185 DVDSFLPEFQPQ-VMLDPDEPMSLGTFTDPDYYMEARYEVEKAMERSRKIIERACREFSE 243

Query: 246 KFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVEE 305
            FGR+Y  +EEYR +DAEII V MGS+  TL++ +D+ R++G  VG  K+ V+RPFP EE
Sbjct: 244 MFGREYGLVEEYRCEDAEIILVAMGSVCSTLREVIDELRDKGKAVGLLKVRVHRPFPAEE 303

Query: 306 IRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDVTFNQL 365
           I+   +    +A ++K+I+  + GA++T+ SA L +      +  FI GLGGRD+T   +
Sbjct: 304 IKSAVRNASKVAVLDKNITFSVGGALYTEISALLRDRE----VYGFIVGLGGRDITPAHI 359

Query: 366 DEALSIAKEALEKGKVEKPIHWIGLRKE 393
           +E +   +        E+ + WIGL++E
Sbjct: 360 EEIVRRTENP------ERSVTWIGLKEE 381


>sp|Q57715|PORA_METJA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
           CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
           SUBUNIT) >gi|2127892|pir||D64333 pyruvate synthase (EC
           1.2.7.1) alpha chain - Methanococcus jannaschii
           >gi|1590995|gb|AAB98254.1| (U67482) pyruvate ferredoxin
           oxidoreductase, subunit alpha (porA) [Methanococcus
           jannaschii]
           Length = 389
           
 Score =  411 bits (1045), Expect = e-114
 Identities = 214/390 (54%), Positives = 279/390 (70%), Gaps = 12/390 (3%)

Query: 6   VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65
           V+    AAA AAKLA   VIAA+PITP T   EK++EFVANGELDAE+IKVESEHSA+SA
Sbjct: 9   VITGTSAAAEAAKLADVDVIAAYPITPQTTCVEKLAEFVANGELDAEYIKVESEHSAMSA 68

Query: 66  LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125
            +GA+A G RTFTATASQGLALMHE+LFIA+GMRLPIVM + NRALSAPINIWND QD+I
Sbjct: 69  CIGAAATGARTFTATASQGLALMHEMLFIASGMRLPIVMMVANRALSAPINIWNDHQDSI 128

Query: 126 SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQE 185
           ++RD+GWIQ Y E+NQE LD I+ AYK+AE+E VLLP MV  D FILTHTVEPV IP  E
Sbjct: 129 AERDSGWIQIYVEDNQETLDSIIQAYKIAENEDVLLPVMVCLDGFILTHTVEPVTIPKAE 188

Query: 186 VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEK 245
            V EFLG YEPKHAYLDP RPITQG +  P  YME R  + EAME A+KVI +   EF +
Sbjct: 189 RVREFLGVYEPKHAYLDPDRPITQGPVGVPDCYMETRKQIEEAMERAKKVIRDVNEEFAE 248

Query: 246 KFGRKYQK--IEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPV 303
            F RKY    +E Y  D+A+ + V MGS+ GT+K  +D+ ++EG  VG  ++  +RPFP 
Sbjct: 249 WFKRKYGNGLVEAYNLDNADTVLVAMGSVCGTIKYVIDELKKEGKNVGLLRIRAFRPFPK 308

Query: 304 EEIRELAKKTKVLAFIEKDISMGL-YGAVFTDASAALINESEKPLMLDFIAGLGGRDVTF 362
           E+++EL K    +A ++K+IS+G   GA+  + ++ L N+     + ++I GLGGRD+  
Sbjct: 309 EDVKELLKDANNIAVLDKNISLGFNKGALGIEMASILKNKK----VCNYIVGLGGRDIKI 364

Query: 363 NQLDEALSIAKEALEKGKVEKPIHWIGLRK 392
           + +   ++  ++A +   +     W+GL++
Sbjct: 365 DDIKTIINHVEKAEDDSTL-----WVGLKE 389


>sp|Q51801|VORA_PYRFU KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (VOR) (2-OXOISOVALERATE
           OXIDOREDUCTASE ALPHA CHAIN) (2-OXOISOVALERATE-FERREDOXIN
           OXIDOREDUCTASE ALPHA SUBUNIT) >gi|11280154|pir||T45085
           2-oxoisovalerate--ferredoxin oxidoreductase (EC 1.2.7.-)
           alpha chain vorA - Pyrococcus furiosus
           >gi|1197360|emb|CAA59502.1| (X85250) 2-ketovalerate
           ferredoxin oxidoreductase alpha-2 [Pyrococcus furiosus]
           Length = 394
           
 Score =  392 bits (997), Expect = e-108
 Identities = 206/392 (52%), Positives = 275/392 (69%), Gaps = 3/392 (0%)

Query: 2   PIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHS 61
           PIR V+  N AAA+AA  A+ +V+AA+PITP T + EKI+EF+ANGE D ++I VESEHS
Sbjct: 5   PIRKVVSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHS 64

Query: 62  AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDW 121
           A++A +GASA G RTFTAT++QGLALMHE+L  AAG RLPIVM   NRA++ P ++W+D 
Sbjct: 65  AMAACIGASATGARTFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQ 124

Query: 122 QDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEI 181
            D++SQRDTGW+QFYAENNQE  D +L+AYKVA  E V +PAMV   AFIL+HT + VE+
Sbjct: 125 TDSLSQRDTGWMQFYAENNQEVYDGVLMAYKVA--ETVNVPAMVVESAFILSHTYDVVEM 182

Query: 182 PDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFA 241
             QE+VDEFL   +P ++  +   PI  G LA P  Y E RY + +A E A+KVI E   
Sbjct: 183 IPQELVDEFLPPRKPLYSLANFDEPIAVGALATPNDYYEFRYKLAKAHEEAKKVIKEVGK 242

Query: 242 EFEKKFGRKY-QKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300
           EF ++FGR Y Q IE    DDA+ +F+ MGSL GT+K+ VD  R+EGYKVG AK+  +RP
Sbjct: 243 EFGERFGRDYSQMIETGYIDDADFVFMGMGSLMGTVKEAVDLLRKEGYKVGYAKVRWFRP 302

Query: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV 360
           FP EE+ E+A+  K +A ++++ S G  G +FT++  AL N S  PLM ++I GLGGRDV
Sbjct: 303 FPKEELVEIAESVKGIAVLDRNFSFGQEGILFTESKGALYNSSAHPLMKNYIVGLGGRDV 362

Query: 361 TFNQLDEALSIAKEALEKGKVEKPIHWIGLRK 392
           T   +       K+ +E GKV+K + W  L++
Sbjct: 363 TVKDIKAIADDMKKVIESGKVDKEVVWYHLKR 394


>pir||A71114 probable ferredoxin oxidoreductase alpha subunit - Pyrococcus
           horikoshii >gi|3257088|dbj|BAA29771.1| (AP000003) 397aa
           long hypothetical ferredoxin oxidoreductase alpha
           subunit [Pyrococcus horikoshii]
           Length = 397
           
 Score =  388 bits (986), Expect = e-107
 Identities = 201/392 (51%), Positives = 271/392 (68%), Gaps = 3/392 (0%)

Query: 2   PIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHS 61
           PI+ V+  N AAA+AA  A+ +V+AA+PITP T + EKI+EF+ANGE D ++I VESEHS
Sbjct: 8   PIKKVVSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHS 67

Query: 62  AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDW 121
           A++A +GASA G R FTAT++QGLALMHE+L  AAG RLPIVM   NRA++ P ++W+D 
Sbjct: 68  AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGSRLPIVMVNVNRAMAPPWSVWDDQ 127

Query: 122 QDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEI 181
            D++SQRDTGW+QFYAENNQE  D +L+AYKVA  E V +P M+   AFIL+HT E V +
Sbjct: 128 TDSLSQRDTGWMQFYAENNQEVYDGVLMAYKVA--ETVNIPTMIIESAFILSHTYEVVNM 185

Query: 182 PDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFA 241
             QE+VDEFL   +P +   D + PI  G LA PA Y E RY + +A E A+KVI     
Sbjct: 186 IPQELVDEFLPPRKPLYTLTDFENPIAVGALATPADYYEFRYKIAKAHEEAKKVIKSVGK 245

Query: 242 EFEKKFGRKYQK-IEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300
           EF ++FGR Y K IE    +DA+ +F+ MGSL GT+K+ VD  R+EGYKVG AK+  +RP
Sbjct: 246 EFGERFGRDYSKMIETGYIEDADFVFMGMGSLMGTVKEAVDLLRKEGYKVGYAKVRWFRP 305

Query: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV 360
           FP EE+ E+A+  K +A ++++ S G  G +FT+A  AL N   +P+M D+I GLGGRD 
Sbjct: 306 FPKEELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNTGVRPIMKDYIVGLGGRDF 365

Query: 361 TFNQLDEALSIAKEALEKGKVEKPIHWIGLRK 392
           T   +       K+ +E GK++K I W  L++
Sbjct: 366 TVRDVKAIAEDMKKVVESGKLDKEIEWYHLKR 397


>sp|O58413|VORA_PYRHO KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (VOR) (2-OXOISOVALERATE
           OXIDOREDUCTASE ALPHA CHAIN) (2-OXOISOVALERATE-FERREDOXIN
           OXIDOREDUCTASE ALPHA SUBUNIT)
           Length = 394
           
 Score =  388 bits (986), Expect = e-107
 Identities = 201/392 (51%), Positives = 271/392 (68%), Gaps = 3/392 (0%)

Query: 2   PIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHS 61
           PI+ V+  N AAA+AA  A+ +V+AA+PITP T + EKI+EF+ANGE D ++I VESEHS
Sbjct: 5   PIKKVVSGNYAAAYAALHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHS 64

Query: 62  AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDW 121
           A++A +GASA G R FTAT++QGLALMHE+L  AAG RLPIVM   NRA++ P ++W+D 
Sbjct: 65  AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGSRLPIVMVNVNRAMAPPWSVWDDQ 124

Query: 122 QDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEI 181
            D++SQRDTGW+QFYAENNQE  D +L+AYKVA  E V +P M+   AFIL+HT E V +
Sbjct: 125 TDSLSQRDTGWMQFYAENNQEVYDGVLMAYKVA--ETVNIPTMIIESAFILSHTYEVVNM 182

Query: 182 PDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFA 241
             QE+VDEFL   +P +   D + PI  G LA PA Y E RY + +A E A+KVI     
Sbjct: 183 IPQELVDEFLPPRKPLYTLTDFENPIAVGALATPADYYEFRYKIAKAHEEAKKVIKSVGK 242

Query: 242 EFEKKFGRKYQK-IEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300
           EF ++FGR Y K IE    +DA+ +F+ MGSL GT+K+ VD  R+EGYKVG AK+  +RP
Sbjct: 243 EFGERFGRDYSKMIETGYIEDADFVFMGMGSLMGTVKEAVDLLRKEGYKVGYAKVRWFRP 302

Query: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV 360
           FP EE+ E+A+  K +A ++++ S G  G +FT+A  AL N   +P+M D+I GLGGRD 
Sbjct: 303 FPKEELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNTGVRPIMKDYIVGLGGRDF 362

Query: 361 TFNQLDEALSIAKEALEKGKVEKPIHWIGLRK 392
           T   +       K+ +E GK++K I W  L++
Sbjct: 363 TVRDVKAIAEDMKKVVESGKLDKEIEWYHLKR 394


>pir||B75047 probable 2-oxoisovalerate--ferredoxin oxidoreductase (EC 1.2.7.-)
           alpha chain PAB1472 [similarity] - Pyrococcus abyssi
           (strain Orsay) >gi|5458784|emb|CAB50271.1| (AJ248287)
           KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORA (EC 1.-.-.-)
           (VOR) [Pyrococcus abyssi]
           Length = 395
           
 Score =  383 bits (972), Expect = e-105
 Identities = 196/392 (50%), Positives = 274/392 (69%), Gaps = 3/392 (0%)

Query: 2   PIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHS 61
           PI+ V+  N AAA+A   A+ +V+AA+PITP T + EKI+EF+ANGE D ++I VESEHS
Sbjct: 6   PIKKVVSGNYAAAYAVLHARVQVVAAYPITPQTSIIEKIAEFIANGEADIQYIPVESEHS 65

Query: 62  AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDW 121
           A++A +GASA G R FTAT++QGLALMHE+L  AAG RLPIVM   NRA++ P ++W+D 
Sbjct: 66  AMAACIGASATGARVFTATSAQGLALMHEMLHWAAGARLPIVMVDVNRAMAPPWSVWDDQ 125

Query: 122 QDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEI 181
            D++SQRDTGW+QFYAENNQE  D +L+A+KVA  E V +PAMV   AFIL+HT E V +
Sbjct: 126 TDSLSQRDTGWMQFYAENNQEVYDGVLMAFKVA--ETVNVPAMVVESAFILSHTYEIVNM 183

Query: 182 PDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFA 241
             QE+VDEFL   +P ++  D + PI  G LA PA Y E RY +  A E A+KVI +   
Sbjct: 184 IPQELVDEFLPPRKPLYSLADFENPIAVGALATPADYYEFRYKLARAHEEAKKVIKDVGR 243

Query: 242 EFEKKFGRKY-QKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300
           EF ++FGR Y + IE+   DDA+ +F+ MGSL GT+K+ V+  R++GYKVG AK+  +RP
Sbjct: 244 EFGERFGRDYSEMIEKAYIDDADFVFMGMGSLMGTVKEAVELLRKQGYKVGYAKVRWFRP 303

Query: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV 360
           FP EE+ E+A+  K +A ++++ S G  G +FT+A  AL N   +P+M ++I GLGGRD 
Sbjct: 304 FPREELLEIAESVKGIAVLDRNFSFGQEGILFTEAKGALYNNGARPIMKNYIVGLGGRDF 363

Query: 361 TFNQLDEALSIAKEALEKGKVEKPIHWIGLRK 392
           T + +       K+ +E GK+++ + W  L++
Sbjct: 364 TVSDVKAIAEDMKKVIESGKLDREVEWYHLKR 395


>emb|CAA59457.1| (X85171) alpha subunit of pyruvate ferredoxin oxidoreductase
           [Thermotoga maritima]
           >gi|4980501|gb|AAD35111.1|AE001690_5 (AE001690) pyruvate
           ferredoxin oxidoreductase, alpha subunit [Thermotoga
           maritima]
           Length = 394
           
 Score =  340 bits (863), Expect = 2e-92
 Identities = 176/389 (45%), Positives = 251/389 (64%), Gaps = 3/389 (0%)

Query: 4   RTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAI 63
           R  +   EA A A +  +P V+AA+PITP T + E  + FVA+G +  E I VESEHSA+
Sbjct: 9   RVAVTGAEAVANAMRQIEPDVVAAYPITPQTPIVEYFARFVADGVVRTEMIPVESEHSAM 68

Query: 64  SALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQD 123
           SA+VGA+AAG R  TAT++ GLALMHE+++IAA  RLPIVM + NRALS PINI  D  D
Sbjct: 69  SAVVGAAAAGARAMTATSANGLALMHEIVYIAASYRLPIVMPVVNRALSGPINIHCDHSD 128

Query: 124 TISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPD 183
            +++RD+GWIQ +AE NQEA D  +LA ++AE E V LP MV  D FIL+H VEPVE   
Sbjct: 129 AMAERDSGWIQLFAETNQEAYDFTILAVRLAEHEDVRLPVMVNLDGFILSHGVEPVEFYP 188

Query: 184 QEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEF 243
            E+V +F+GE +P +  LD + P+T G L    +Y E +    EAMEN +KV  E   EF
Sbjct: 189 DELVKKFVGELKPMYPLLDTEHPVTWGPLDLYDYYFEHKRQQIEAMENVKKVFPEIAKEF 248

Query: 244 EKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPV 303
           E+ FGRKY  +E YR +DAE + V +GS   T+K  VD+ REEGYKVG+ K+ ++RPFP 
Sbjct: 249 EETFGRKYWFVEPYRMEDAEHVMVALGSTNSTIKYVVDELREEGYKVGSLKIWMFRPFPK 308

Query: 304 EEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDVTFN 363
           E+++EL    K +  +++ +S G    ++    +AL   + +P++  ++ GLGGRD+   
Sbjct: 309 EQLQELLNGRKSVVVLDRAVSFGAEAPLYEAVKSALYEVAARPMLGSYVYGLGGRDIKPE 368

Query: 364 QLDEALSIAKEALEKGKVEKPIHWIGLRK 392
            + +A    ++A+    +     ++GLR+
Sbjct: 369 HIRKAF---EDAINGNLIADEQRYLGLRE 394


>sp|O05651|PORA_THEMA PYRUVATE SYNTHASE SUBUNIT PORA (PYRUVATE OXIDOREDUCTASE ALPHA
           CHAIN) (POR) (PYRUVIC-FERREDOXIN OXIDOREDUCTASE ALPHA
           SUBUNIT) >gi|7449946|pir||C72427 pyruvate synthase (EC
           1.2.7.1) alpha chain - Thermotoga maritima (strain MSB8)
           Length = 392
           
 Score =  340 bits (863), Expect = 2e-92
 Identities = 176/389 (45%), Positives = 251/389 (64%), Gaps = 3/389 (0%)

Query: 4   RTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAI 63
           R  +   EA A A +  +P V+AA+PITP T + E  + FVA+G +  E I VESEHSA+
Sbjct: 7   RVAVTGAEAVANAMRQIEPDVVAAYPITPQTPIVEYFARFVADGVVRTEMIPVESEHSAM 66

Query: 64  SALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQD 123
           SA+VGA+AAG R  TAT++ GLALMHE+++IAA  RLPIVM + NRALS PINI  D  D
Sbjct: 67  SAVVGAAAAGARAMTATSANGLALMHEIVYIAASYRLPIVMPVVNRALSGPINIHCDHSD 126

Query: 124 TISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPD 183
            +++RD+GWIQ +AE NQEA D  +LA ++AE E V LP MV  D FIL+H VEPVE   
Sbjct: 127 AMAERDSGWIQLFAETNQEAYDFTILAVRLAEHEDVRLPVMVNLDGFILSHGVEPVEFYP 186

Query: 184 QEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEF 243
            E+V +F+GE +P +  LD + P+T G L    +Y E +    EAMEN +KV  E   EF
Sbjct: 187 DELVKKFVGELKPMYPLLDTEHPVTWGPLDLYDYYFEHKRQQIEAMENVKKVFPEIAKEF 246

Query: 244 EKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPV 303
           E+ FGRKY  +E YR +DAE + V +GS   T+K  VD+ REEGYKVG+ K+ ++RPFP 
Sbjct: 247 EETFGRKYWFVEPYRMEDAEHVMVALGSTNSTIKYVVDELREEGYKVGSLKIWMFRPFPK 306

Query: 304 EEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDVTFN 363
           E+++EL    K +  +++ +S G    ++    +AL   + +P++  ++ GLGGRD+   
Sbjct: 307 EQLQELLNGRKSVVVLDRAVSFGAEAPLYEAVKSALYEVAARPMLGSYVYGLGGRDIKPE 366

Query: 364 QLDEALSIAKEALEKGKVEKPIHWIGLRK 392
            + +A    ++A+    +     ++GLR+
Sbjct: 367 HIRKAF---EDAINGNLIADEQRYLGLRE 392


>emb|CAC11767.1| (AL445064) probable 2-ketovalerate ferredoxin oxidoreductase
           alpha-2 chain [Thermoplasma acidophilum]
           Length = 402
           
 Score =  326 bits (827), Expect = 3e-88
 Identities = 171/391 (43%), Positives = 254/391 (64%), Gaps = 10/391 (2%)

Query: 4   RTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAI 63
           RT+M  N+A A+ AKLA+ K I+A+PITP T + EK++  +AN ELDA++++VESEHSA+
Sbjct: 18  RTIMTGNDAVAYGAKLARVKFISAYPITPQTTIVEKLASMIANDELDAKYVEVESEHSAL 77

Query: 64  SALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQD 123
           +A+  +   GVR++TAT+S GL  MHE+L   AG RLPIVM++ NRA+  P NIW D  D
Sbjct: 78  AAVFASELTGVRSYTATSSHGLLYMHEMLHWVAGQRLPIVMSVVNRAIGPPWNIWADQSD 137

Query: 124 TISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPD 183
           TI+QRDTGW+Q Y+E+NQEA+D I++ YK+AE+  V+LP M   DAFIL+HT EPV + D
Sbjct: 138 TINQRDTGWMQVYSESNQEAMDTIIMGYKIAENSGVMLPLMSMEDAFILSHTSEPVTMRD 197

Query: 184 QEVVDEFLGEYEPKHAYLDPKRPITQGTLAFP-AHYMEARYLVWEAMENARKVIDEAFAE 242
           Q++V+E+L + + K   +DP+ P+  G+   P   +ME +  + ++M NARKVI E   +
Sbjct: 198 QDLVNEYLPDLDLKFR-IDPENPMGYGSYDTPDGSFMEFKKDMIDSMNNARKVIKEETQK 256

Query: 243 FEKKFGRKY-QKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPF 301
           F + F   Y   IE YR DDA+   + MG++A T +  +D+ RE G  +G  ++  +RPF
Sbjct: 257 FNEMFETNYGALIERYRMDDADYAIIAMGTVASTARFVIDRLRENGLNIGLIRIRYFRPF 316

Query: 302 PVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDVT 361
           P +EI E  K  K    I++ +S GL G  +++  + L      P+   FI G+GGRDV 
Sbjct: 317 PYDEILEDLKNVKSAGVIDRSVSFGLAGVTYSEVISGLYGRINIPVS-SFIVGIGGRDV- 374

Query: 362 FNQLDEALSIAKEALEKGKVEKPIHWIGLRK 392
             ++++  SIA E +  G      HWI +++
Sbjct: 375 --RIEDIESIA-ETIRNGST--GTHWINVKR 400


>gi|11499291 pyruvate ferredoxin oxidoreductase, subunit alpha (porA)
           [Archaeoglobus fulgidus] >gi|7449947|pir||D69462
           pyruvate synthase (EC 1.2.7.1) alpha chain -
           Archaeoglobus fulgidus >gi|2648853|gb|AAB89548.1|
           (AE000986) pyruvate ferredoxin oxidoreductase, subunit
           alpha (porA) [Archaeoglobus fulgidus]
           Length = 391
           
 Score =  322 bits (816), Expect = 5e-87
 Identities = 178/377 (47%), Positives = 239/377 (63%), Gaps = 3/377 (0%)

Query: 3   IRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGEL-DAEFIKVESEHS 61
           +R V++   + A++ KL KP VI A+PITP T + E ++   ANGEL DAE+I  ESE  
Sbjct: 1   MRKVVRGFYSVAYSVKLCKPNVICAYPITPQTEIVENLAAMYANGELGDAEYITAESEFG 60

Query: 62  AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDW 121
           A S LVGASAAG R FTAT SQGL LM EVLF AAGMRLPIV+   NRALSAP++IWND 
Sbjct: 61  AASMLVGASAAGARVFTATCSQGLILMSEVLFNAAGMRLPIVLVNTNRALSAPLSIWNDH 120

Query: 122 QDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEI 181
           QD+++ RD G +Q Y ENNQEA D+I  AYKVAE+ +VLLP M+  D + LTH  EPV++
Sbjct: 121 QDSMAMRDAGIMQVYVENNQEAHDMIPQAYKVAENRKVLLPFMICMDGYKLTHAYEPVDL 180

Query: 182 PDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFA 241
            +QE VD FL  YEP  AY+  K+P+  G  A P  YME R  + +AME ARK++ + F 
Sbjct: 181 LEQETVDSFLPPYEPA-AYMTTKKPLAFGCYAPPHVYMEFRVAMQQAMERARKIMLDVFK 239

Query: 242 EFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPF 301
           E+ +  GR +         D++I  V MGS+ G L+  V++ R EG  VG  K+  +RPF
Sbjct: 240 EWGELTGRDWGGHITVDFPDSKIFVVAMGSVVGLLRKVVEELRGEGLSVGLIKIRTFRPF 299

Query: 302 PVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDVT 361
           PVEE+RE  K  + +  +++ +S G  G V  +  +A+   S   +   F  GLGGRD+ 
Sbjct: 300 PVEELREALKDAEKVIVLDRSVSFGYEGPVSIELKSAIYGHSSAEI-YSFAVGLGGRDMP 358

Query: 362 FNQLDEALSIAKEALEK 378
            + L++ +    E  EK
Sbjct: 359 KDFLEKIIRDVAEGREK 375


>gb|AAK41454.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase
           alpha chain) (porA-1) [Sulfolobus solfataricus]
           Length = 385
           
 Score =  308 bits (781), Expect = 6e-83
 Identities = 160/352 (45%), Positives = 232/352 (65%), Gaps = 5/352 (1%)

Query: 10  NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISALVGA 69
           N A A+A K AKPKV+A FPITP T + EK+SE++++ EL AE IKVESEHSA++++ GA
Sbjct: 14  NHAVAYAVKQAKPKVLAVFPITPQTTMLEKLSEYISSEELKAELIKVESEHSALASIYGA 73

Query: 70  SAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTISQRD 129
           + AG R FTAT+SQGL  M E+++ A G R+PIV A+  RA++ P +IW+D QD +S+RD
Sbjct: 74  ALAGARVFTATSSQGLLYMTEMIYWAGGQRVPIVAAVATRAIAEPWSIWDDHQDFVSKRD 133

Query: 130 TGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEVVDE 189
             WIQ  AEN QEA D+ + A++++EDERV+LP M+GFD FILTHT+E +E+ +   VD 
Sbjct: 134 AIWIQIMAENVQEAYDMTIQAFRISEDERVILPVMMGFDGFILTHTMERIEVLEDNEVDN 193

Query: 190 FLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEKKFGR 249
           FL   +     +D   PI  G +A P  Y++ RY   +AME A+ VI+E   E+E+  GR
Sbjct: 194 FLPPRQ--FNLIDFSDPIAIGPIATPEEYIKYRYEAMKAMERAKGVIEEIMGEYERISGR 251

Query: 250 K-YQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVEEIRE 308
           K +  +E Y+ +DA+ +FVTMG+ +G  K  VD+ R+ G K G  K+ V+RPFP E++ E
Sbjct: 252 KQHGLVECYKCEDAKYVFVTMGAWSGDGKAAVDRLRDSGVKTGLLKIRVFRPFPKEKVEE 311

Query: 309 LAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDV 360
             +  K +   ++  S G  G +  +  AAL     +  +   +AG+GG+DV
Sbjct: 312 YLRSMKGVVVFDRAYSYGYGGILVNEIKAALY--GYRVPVYSVVAGIGGKDV 361


>gb|AAK42867.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase
           alpha chain) (porA-2) [Sulfolobus solfataricus]
           Length = 400
           
 Score =  282 bits (714), Expect = 5e-75
 Identities = 154/367 (41%), Positives = 220/367 (58%), Gaps = 7/367 (1%)

Query: 3   IRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSA 62
           IR ++  NEA A   KLA+  V   +PITP T + EK++E  A GE++ E ++VESEHSA
Sbjct: 2   IRKIISGNEAVALGVKLARVGVTGIYPITPQTTIIEKLAEMRAKGEIETEIVRVESEHSA 61

Query: 63  ISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQ 122
           ++A  GA+  GVR FTATASQGL  MHE+++  AG R+P+VM +G RA+ AP NIWN+  
Sbjct: 62  MAATFGAALGGVRAFTATASQGLLYMHEMVWWVAGSRVPVVMVVGTRAVGAPWNIWNEHT 121

Query: 123 DTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIP 182
           D  S+RD+GWI  +A N QEALDL L A++++EDERV LP M+G D FIL+HT   V IP
Sbjct: 122 DFTSERDSGWIMAFASNPQEALDLTLQAFRISEDERVFLPMMIGMDGFILSHTKTNVLIP 181

Query: 183 DQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAE 242
           DQ+ VD+FL      +  +DP+ P+  G +  P  YM  R  +  A+ N+  VI E   E
Sbjct: 182 DQDQVDDFLPPRRQPYV-IDPEDPVGMGNIFPPEGYMRLRESIDLALRNSEDVIKEIGRE 240

Query: 243 FEKKFG--RKYQKIE-EYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYR 299
           + KK      Y  +   Y+ +DA+   V MG+ AG   + VD  RE+G K+G  ++   R
Sbjct: 241 YNKKINPLGDYSTLNVSYKLEDADYAVVLMGAWAGDAMEAVDTLREKGIKIGMLRIRYLR 300

Query: 300 PFPVEEIRELAKKTKVLAFIEKDISMGLYGA-VFTDASAALINESEKPLMLDFIAGLGGR 358
           P+  +EIR   K  K +  +++  S G  G  ++ +  + + N    P +   ++GLGG 
Sbjct: 301 PWSEKEIRNTLKDKKAVLVLDRSTSFGRGGGPLYVEIKSTISN--VVPQIKGVVSGLGGV 358

Query: 359 DVTFNQL 365
            V  N L
Sbjct: 359 TVNKNDL 365


>pir||H71857 pyruvate ferrodoxin oxidoreductase - Helicobacter pylori  (strain
           J99) >gi|4155626|gb|AAD06616.1| (AE001531) Pyruvate
           ferrodoxin oxidoreductase [Helicobacter pylori J99]
           Length = 407
           
 Score =  277 bits (700), Expect = 2e-73
 Identities = 156/389 (40%), Positives = 232/389 (59%), Gaps = 3/389 (0%)

Query: 6   VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65
           V   N A++ A + A+  VIAA+PITPST + +    F  NG +D EF+ VESEH+A+SA
Sbjct: 12  VWDGNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYVDGEFVLVESEHAAMSA 71

Query: 66  LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125
            VGA+AAG R  TAT+SQGLALM EVL+ A+GMRLPIV+ + NRAL+AP+NI  D  D  
Sbjct: 72  CVGAAAAGGRVSTATSSQGLALMVEVLYQASGMRLPIVLNLVNRALAAPLNIHGDHSDMY 131

Query: 126 SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQE 185
             RD+GWI     N QEA D  L+A+++AE ++V +P +V  D F+ +HTV+ V      
Sbjct: 132 LSRDSGWISLCTCNPQEAYDFTLMAFRIAEHQKVRVPTIVNQDGFLCSHTVQNVRPLSDA 191

Query: 186 VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEK 245
           V  +F+GEY+ KH+ LD  +P++ G  A    + E +  +  A+ +A  VI+E F +F K
Sbjct: 192 VAYQFVGEYQTKHSLLDFDKPVSYGAQAEEEWHYEHKAQLHHAIMSASSVIEEVFNDFAK 251

Query: 246 KFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVEE 305
             GR+Y   + ++ +DAEI    +G+   +      + R++G K G A +   RPFP E 
Sbjct: 252 LTGRQYHLTKTFQLEDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSLRPFPYER 311

Query: 306 IRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINE--SEKPLMLDFIAGLGGRDVTFN 363
           + +  K  K LA ++K    G  GA+F + ++A+     ++ P++ ++I GLG RD+T  
Sbjct: 312 LGQDLKNLKALAILDKSSPAGAMGAMFNEVTSAVYQTQGTKHPVVSNYIYGLGERDMTIV 371

Query: 364 QLDEALSIAKEALEKGKVEKPI-HWIGLR 391
            L E      E   KG +  P   ++GLR
Sbjct: 372 HLCEIFEEINEDALKGTLTHPTQQFVGLR 400


>pir||F64658 pyruvate synthase (EC 1.2.7.1) alpha chain - Helicobacter pylori
           (strain 26695) >gi|2314261|gb|AAD08154.1| (AE000617)
           pyruvate ferredoxin oxidoreductase, alpha subunit
           [Helicobacter pylori 26695]
           Length = 407
           
 Score =  275 bits (696), Expect = 6e-73
 Identities = 155/388 (39%), Positives = 231/388 (58%), Gaps = 3/388 (0%)

Query: 6   VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65
           V   N A++ A + A+  VIAA+PITPST + +    F  NG +D EF+ VESEH+A+SA
Sbjct: 12  VWDGNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYVDGEFVLVESEHAAMSA 71

Query: 66  LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125
            VGA+AAG R  TAT+SQGLALM EVL+ A+GMRLPIV+ + NRAL+AP+NI  D  D  
Sbjct: 72  CVGAAAAGGRVSTATSSQGLALMVEVLYQASGMRLPIVLNLVNRALAAPLNIHGDHSDMY 131

Query: 126 SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQE 185
             RD+GWI     N QEA D  L+A+++AE ++V +P +V  D F+ +HTV+ V      
Sbjct: 132 LSRDSGWISLCTCNPQEAYDFTLMAFRIAEHQKVRVPTIVNQDGFLCSHTVQNVRPLSDA 191

Query: 186 VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEK 245
           V  +F+GEY+ KH+ LD  +P++ G  A    + E +  +  A+ +A  VI+E F +F K
Sbjct: 192 VAYQFVGEYQTKHSLLDFDKPVSYGAQAEEEWHYEHKAQLHHAIMSASSVIEEVFNDFAK 251

Query: 246 KFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVEE 305
             GR+Y   + ++ +DAEI    +G+   +      + R++G K G A +   RPFP E 
Sbjct: 252 LTGRQYHLTKTFQLEDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSLRPFPYER 311

Query: 306 IRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINE--SEKPLMLDFIAGLGGRDVTFN 363
           + +  K  K LA ++K    G  GA+F + ++A+     ++ P++ ++I GLG RD+T  
Sbjct: 312 LGQDLKNLKALAILDKSSPAGTMGAMFNEVTSAVYQTQGTKHPVVSNYIYGLGERDMTIA 371

Query: 364 QLDEALSIAKEALEKGKVEKPI-HWIGL 390
            L E      E   KG +  P   ++GL
Sbjct: 372 HLCEIFEEINEDALKGTLTHPTQQFVGL 399


>gb|AAC02293.1| (AF013980) pyruvate:ferredoxin oxidoreductase alpha subunit
           [Helicobacter pylori]
           Length = 396
           
 Score =  273 bits (691), Expect = 2e-72
 Identities = 152/375 (40%), Positives = 228/375 (60%), Gaps = 2/375 (0%)

Query: 6   VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65
           V   N A++ A + A+  VIAA+PITPST + +    F  NG +D EF+ VESEH+A+SA
Sbjct: 12  VWDGNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYIDGEFVLVESEHAAMSA 71

Query: 66  LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125
            VGA+AAG R  TAT+SQGLALM EVL+ A+GMRLPIV+ + NRAL+AP+NI  D  D  
Sbjct: 72  CVGAAAAGGRVSTATSSQGLALMVEVLYQASGMRLPIVLNLVNRALAAPLNIHGDHSDMY 131

Query: 126 SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQE 185
             RD+GWI     N QEA D  L+A+K+AE ++V +P +V  D F+ +HTV+ V      
Sbjct: 132 LSRDSGWISLCTCNPQEAYDFTLMAFKIAEHQKVRVPTIVNQDGFLCSHTVQNVRPLSDA 191

Query: 186 VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEK 245
           V  +F+GEY+ KH+ LD  +P++ G  A    + E +  +  A+ +A  VI+E F +F K
Sbjct: 192 VAYQFVGEYQTKHSLLDFDKPVSYGAQAEEEWHYEHKAQLHHAIMSASSVIEEVFNDFAK 251

Query: 246 KFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVEE 305
             GR+Y   + ++ +DAEI    +G+   +      + R++G K G A +   RPFP E+
Sbjct: 252 LTGRQYHLTKTFQLEDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSLRPFPYEK 311

Query: 306 IRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINE--SEKPLMLDFIAGLGGRDVTFN 363
           + +  K  K LA ++K    G  GA+F + ++A+     ++ P++ ++I GLG RD+T  
Sbjct: 312 LGQDLKNLKALAILDKSSPAGAMGAMFNEVTSAVYQTQGTKHPVVSNYIYGLGERDMTIA 371

Query: 364 QLDEALSIAKEALEK 378
            L + L  + + L K
Sbjct: 372 HLWKFLKKSMKTLLK 386


>gb|AAK42308.1| Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase
           alpha chain) (porA-like) [Sulfolobus solfataricus]
           Length = 415
           
 Score =  264 bits (667), Expect = 2e-69
 Identities = 145/400 (36%), Positives = 221/400 (55%), Gaps = 15/400 (3%)

Query: 6   VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65
           +M   +A A AA  A   V+AA+PI P T V + IS+ +A+GELDAEFI  E EH     
Sbjct: 13  LMNGTQAVAHAAMYADVDVVAAYPIRPYTEVMDTISKLIADGELDAEFIVAEGEHGQFET 72

Query: 66  LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125
           +  AS AG RT   ++  G     E + + A  R P+V  IGNRAL  P     +  D +
Sbjct: 73  VKHASLAGARTLVGSSGVGWLYAMEAIVVTATDRAPVVAIIGNRALDDPGAYGVEHNDAL 132

Query: 126 SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQE 185
             RD GW+  + +  QEA D  LLAY++AED+RVLLP  +  D   LTH+ + V +P +E
Sbjct: 133 MVRDVGWLLVWVDTAQEAFDTALLAYRIAEDQRVLLPLGISMDGGFLTHSEQIVRLPPRE 192

Query: 186 VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEK 245
           +V  FL  Y      + P  PIT          ME R    EAME AR VI EA+ EF+K
Sbjct: 193 LVKNFLPPYNRGKYLVHPDNPITVAPQVNEDWVMEIRRQHEEAMERARSVIVEAYEEFKK 252

Query: 246 KFGR-----------KYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAK 294
            FGR           +   +E Y  DDAE++ + MG+++  +K  +   R +GYKVG  +
Sbjct: 253 VFGRYPGSTSDLQMPENPFVEPYMIDDAEVVLIGMGTVSKPMKVAIKNMRRQGYKVGMLR 312

Query: 295 MTVYRPFPVEEIRELAKKTKVLAFIEKDISMG---LYGAVFTDASAALINESEKPLMLDF 351
           +  +RPFP +++      ++V+  I++D SMG     G ++ +  ++L +  ++P +++F
Sbjct: 313 IRWFRPFPTQDVIRYLANSRVVCVIDRDYSMGSPNRGGVIYHEVRSSLYDLDQRPRVMNF 372

Query: 352 IAGLGGRDVTFNQLDEALSIAKEALEKGKVEKPIHWIGLR 391
           I GLGGR++T   +++ + I  E  +   + KP++W+G+R
Sbjct: 373 IGGLGGREITIQDVEKIIKIGYEHRDT-PITKPVYWVGVR 411


>pir||S74041 pyruvate synthase (EC 1.2.7.1) alpha chain - Sulfolobus
           solfataricus >gi|1707735|emb|CAA69455.1| (Y08256)
           pyruvate-ferredoxin oxidoreductase alpha-2 [Sulfolobus
           solfataricus]
           Length = 415
           
 Score =  264 bits (667), Expect = 2e-69
 Identities = 145/400 (36%), Positives = 221/400 (55%), Gaps = 15/400 (3%)

Query: 6   VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65
           +M   +A A AA  A   V+AA+PI P T V + IS+ +A+GELDAEFI  E EH     
Sbjct: 13  LMNGTQAVAHAAMYADVDVVAAYPIRPYTEVMDTISKLIADGELDAEFIVAEGEHGQFET 72

Query: 66  LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125
           +  AS AG RT   ++  G     E + + A  R P+V  IGNRAL  P     +  D +
Sbjct: 73  VKHASLAGARTLVGSSGVGWLYAMEAIVVTATDRAPVVAIIGNRALDDPGAYGVEHNDAL 132

Query: 126 SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQE 185
             RD GW+  + +  QEA D  LLAY++AED+RVLLP  +  D   LTH+ + V +P +E
Sbjct: 133 MVRDVGWLLVWVDTAQEAFDTALLAYRIAEDQRVLLPLGISMDGGFLTHSEQIVRLPPRE 192

Query: 186 VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEK 245
           +V  FL  Y      + P  PIT          ME R    EAME AR VI EA+ EF+K
Sbjct: 193 LVKNFLPPYNRGKYLVHPDNPITVAPQVNEDWVMEIRRQHEEAMERARSVIVEAYEEFKK 252

Query: 246 KFGR-----------KYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAK 294
            FGR           +   +E Y  DDAE++ + MG+++  +K  +   R +GYKVG  +
Sbjct: 253 VFGRYPGSTSDLQMPENPFVEPYMIDDAEVVLIGMGTVSKPMKVAIKNMRRQGYKVGMLR 312

Query: 295 MTVYRPFPVEEIRELAKKTKVLAFIEKDISMG---LYGAVFTDASAALINESEKPLMLDF 351
           +  +RPFP +++      ++V+  I++D SMG     G ++ +  ++L +  ++P +++F
Sbjct: 313 IRWFRPFPTQDVIRYLANSRVVCVIDRDYSMGSPNRGGVIYHEVRSSLYDLDQRPRVMNF 372

Query: 352 IAGLGGRDVTFNQLDEALSIAKEALEKGKVEKPIHWIGLR 391
           I GLGGR++T   +++ + I  E  +   + KP++W+G+R
Sbjct: 373 IGGLGGREITIQDVEKIIKIGYEHRDT-PITKPVYWVGVR 411


>gi|11499635 2-ketoisovalerate ferredoxin oxidoreductase, subunit alpha (vorA)
           [Archaeoglobus fulgidus] >gi|7449955|pir||D69506
           probable 2-oxoisovalerate--ferredoxin oxidoreductase (EC
           1.2.7.-) alpha chain AF2053 [similarity] - Archaeoglobus
           fulgidus >gi|2648476|gb|AAB89196.1| (AE000961)
           2-ketoisovalerate ferredoxin oxidoreductase, subunit
           alpha (vorA) [Archaeoglobus fulgidus]
           Length = 366
           
 Score =  243 bits (613), Expect = 3e-63
 Identities = 145/368 (39%), Positives = 215/368 (58%), Gaps = 30/368 (8%)

Query: 3   IRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSA 62
           ++ ++ +NEA A A KLAKP VIAA+PITP + + EK+SE V +GELD+ F++VESEHSA
Sbjct: 13  MKKLLTSNEAIAEAVKLAKPDVIAAYPITPQSPIVEKLSEMVDSGELDSRFVRVESEHSA 72

Query: 63  ISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQ 122
           +  ++GA+ AG R FTAT+S GLA M+E+ + AAG RLPIVMA+  R++ AP NI  D  
Sbjct: 73  MGVVIGAATAGARVFTATSSHGLAYMYEMCWWAAGSRLPIVMALAARSIGAPWNIHGDHL 132

Query: 123 DTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIP 182
           D ++ RD GWI   AEN QEA D+ L A+ ++E+  V +P  V  D F ++HT E VE+ 
Sbjct: 133 DLMAMRDLGWIISVAENAQEAFDMTLNAFMLSEE--VNIPVAVAIDGFTMSHTAEVVEVR 190

Query: 183 DQEVVDEFLGEYEPKHAY-LDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFA 241
           + E+          K AY + P   +    + F    M ARY + + +EN+ ++I     
Sbjct: 191 EVEIPPR-------KQAYRILPGMDVALNAVTFGEARMTARYDLAKDLENSAELI----- 238

Query: 242 EFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPF 301
             EK++G     +E YR +DA+   V  G L+G +KD VD  REEG K+G  ++   RPF
Sbjct: 239 --EKEYG---GLVERYRLEDADYAVVVTGGLSGDVKDAVDMLREEGVKMGVLRLKFIRPF 293

Query: 302 PVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGRDVT 361
           P + ++ L  +  V+     D    L G +  + +A  +        ++ +AG+GGR  T
Sbjct: 294 PKKAVKSLPSQVLVVDRANTD----LRGTLSVEVAACGVEN------VNVVAGIGGRYPT 343

Query: 362 FNQLDEAL 369
             +L   L
Sbjct: 344 VEELYSCL 351


>gb|AAC38206.1| (AF021092) PorA subunit of pyruvate:flavodoxin oxidoreductase
           [Helicobacter pylori]
           Length = 408
           
 Score =  230 bits (581), Expect = 2e-59
 Identities = 139/390 (35%), Positives = 214/390 (54%), Gaps = 4/390 (1%)

Query: 6   VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65
           V   N A++ A + A+  VIAA+PITPST + +    F  NG +D +F  VESEH+A+SA
Sbjct: 12  VWDGNTASSNALRQAQIDVIAAYPITPSTPIVQNYGSFKDNGYIDGDFALVESEHAAMSA 71

Query: 66  LVGASAAGVRTFTATASQGLALMHEVLFI-AAGMRLPIVMAIGNRALSAPINIWNDWQDT 124
            VGA+AAG R  TAT+SQG  +         +GMR  IV  + NRAL+AP+NI  D  D 
Sbjct: 72  CVGAAAAGGRVSTATSSQGSGVNGRGFITKVSGMRSAIVGNLVNRALAAPLNIHGDHSDM 131

Query: 125 ISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQ 184
              RD+GWI     N QEA D  L+A+K+ E ++V +P +V  D F+ +HTV+ V     
Sbjct: 132 YLSRDSGWISLCTCNPQEAYDFTLMAFKLGEHQKVRVPTIVNQDGFLCSHTVQNVRPLSD 191

Query: 185 EVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFE 244
            V  +F+GEY+ KH+ +D  +P++ G  A    + E +  +  A+ +A  VI+E F +F 
Sbjct: 192 GVAYQFVGEYQTKHSLVDFDKPVSYGAQAEEEWHYEHKARLHHAIMSASSVIEEVFNDFA 251

Query: 245 KKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVE 304
           K  GR+Y   + ++ +DAEI    +G+   +      + R++G K G A +    P  + 
Sbjct: 252 KLTGRQYHLTKTFQLEDAEIAIFALGTTYESAIVAAKEMRKKGIKAGVATIHSCAPSLMR 311

Query: 305 EIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINE--SEKPLMLDFIAGLGGRDVTF 362
            +    K  K LA ++K    G  GA+F + ++ +     ++ P++ ++I GLG RD+T 
Sbjct: 312 RLGRDLKNLKALAILDKRSPAGAMGAMFNEVTSTVYQTQGTKHPVVSNYIYGLGERDMTI 371

Query: 363 NQLDEALSIAKEALEKGKVEKPI-HWIGLR 391
             L E      E   KG +  P   ++GLR
Sbjct: 372 AHLCEIFEEINEDALKGTLTHPTQQFVGLR 401


>emb|CAB43933.1| (Y17726) pyruvate ferredoxin oxidoreductase [Clostridium
           pasteurianum]
           Length = 1175
           
 Score =  165 bits (413), Expect = 9e-40
 Identities = 119/390 (30%), Positives = 200/390 (50%), Gaps = 16/390 (4%)

Query: 3   IRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELD-----AEFIKVE 57
           I   M  NEAAA+A+  A  +V A +PITPST + E + E+ A+ + +        ++++
Sbjct: 4   IMKTMDGNEAAAYAS-YAFTEVAAIYPITPSTPMAESVDEWSAHDKKNIFDQAVNVVEMQ 62

Query: 58  SEHSAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PIN 116
           SE  A  ++ G+ AAG  T T TASQGL LM   ++  AG +LP V  +  RA++   ++
Sbjct: 63  SEAGAAGSVHGSLAAGALTTTYTASQGLLLMIPNMYKIAGEQLPTVFHVSARAIATHALS 122

Query: 117 IWNDWQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTV 176
           I+ D QD ++ R TG+    + + QEA+DL  +++      +V  P +  FD F  +H  
Sbjct: 123 IFGDHQDVMACRQTGFALLASSSVQEAMDLGCISHLSTIKSKV--PFLHFFDGFRTSHEY 180

Query: 177 EPVEIPDQEVVDEFLGEY----EPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENA 232
           + +EI D E +   + +Y    E +   L+P+ P+ +GT   P  Y + R    +  +  
Sbjct: 181 QKIEIIDYEDLKNLV-DYNSIKEFRDKALNPEHPVVRGTAQNPDIYFQGREASNKFYDAV 239

Query: 233 RKVIDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGA 292
             +++    E +   GR+Y   + Y   DAE I + MGS+  T+ + +D  R +G KVG 
Sbjct: 240 PDIVENYMKEIKSITGREYHPFDYYGAPDAENIIIAMGSVCDTIDESIDYLRNKGEKVGV 299

Query: 293 AKMTVYRPFPVEEIRELAKKT-KVLAFIEKDISMG-LYGAVFTDASAALINESEKPLMLD 350
            K+ +YRPF  +    +  KT K +A +++    G L   ++ D      N +EKP+++ 
Sbjct: 300 IKVHLYRPFSSKYFFNVFPKTVKKIAVLDRTKEPGSLAEPLYLDVVHLFNNSAEKPIIIG 359

Query: 351 FIAGLGGRDVTFNQLDEALSIAKEALEKGK 380
              GLG +D   +Q+    +  K    K K
Sbjct: 360 GRYGLGSKDTRPSQILSVFNNLKSDNPKDK 389


>gb|AAD55756.1|AF132673_1 (AF132673) pyruvate:ferredoxin oxidoreductase [Clostridium
           pasteurianum]
           Length = 1098
           
 Score =  162 bits (407), Expect = 5e-39
 Identities = 110/364 (30%), Positives = 192/364 (52%), Gaps = 16/364 (4%)

Query: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDA-----EFIKVESEHS 61
           M  NEAAA+A+  A  +V A +PITPST + E + E+ A+ + +        ++++SE  
Sbjct: 6   MDGNEAAAYAS-YAFTEVAAIYPITPSTPMAESVDEWSAHDKKNVFDQAVNVVEMQSEAG 64

Query: 62  AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWND 120
           A  ++ G+ AAG  T T TASQGL LM   ++  AG +LP V  +  RA++   ++I+ D
Sbjct: 65  AAGSVHGSLAAGALTTTYTASQGLLLMIPNMYKIAGEQLPTVFHVSARAIATHALSIFGD 124

Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180
            QD ++ R TG+    + + QEA+DL  +++      +V  P +  FD F  +H ++ +E
Sbjct: 125 HQDVMACRQTGFALLASSSVQEAMDLGCISHLSTIKSKV--PFLHFFDGFRTSHEIQKIE 182

Query: 181 IPDQEVVDEFLGEYEPKHAY----LDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVI 236
           + D E +   + + +   A+    L+P+ P+T+GT   P  Y + R    +      +++
Sbjct: 183 VIDYEDLRPLV-DIDAVKAFRNNALNPEHPVTRGTAENPDVYFQGREASNKYYNAIPELV 241

Query: 237 DEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMT 296
           +    E  K  GR+Y     Y  +DAE I + MGS++  +++ +D    +G KVG  K+ 
Sbjct: 242 ENYMGEISKITGREYHLFNYYGAEDAERIIIAMGSISDAIEETIDYLNAKGEKVGVLKVH 301

Query: 297 VYRPFPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLMLDFIAG 354
           ++RPF VE   + + K  K +A +++    G YG  ++ D   A       P+++    G
Sbjct: 302 LFRPFSVEHFFKYIPKTVKKIAVLDRTKEPGSYGEPLYLDVVTAFYQSDLNPVIVGGRYG 361

Query: 355 LGGR 358
           LG +
Sbjct: 362 LGSK 365


>emb|CAB43935.1| (Y17727) pyruvate ferredoxin oxidoreductase [Clostridium
           pasteurianum]
           Length = 1175
           
 Score =  159 bits (397), Expect = 7e-38
 Identities = 112/365 (30%), Positives = 185/365 (50%), Gaps = 16/365 (4%)

Query: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELD-----AEFIKVESEHS 61
           M  N AAA  A  A   V A +PITPS+ + E + E+   G  +      + ++++SE  
Sbjct: 7   MDGNTAAAHIA-YAFTDVTAIYPITPSSPMAEHVDEWAVQGRKNLFGQTVKVMEMQSEAG 65

Query: 62  AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAP-INIWND 120
           A  A+ G+  AG  T T TASQGL LM   ++  AG  LP V  +  RAL+   +NI+ D
Sbjct: 66  AAGAVHGSLQAGALTTTFTASQGLLLMIPNMYKIAGELLPGVFHVSARALATKSLNIFGD 125

Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180
            QD ++ R TG+      + QE +DL  +A+  A   +V  P +  FD F  +H ++ +E
Sbjct: 126 HQDVMAARQTGFALLAEGSVQEVMDLSAVAHLAAIKGKV--PFLNFFDGFRTSHEIQKIE 183

Query: 181 IPDQEVVDEFLGEYEPKHAY----LDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVI 236
           + D E +   + + +   A+    L+P+ P+T+GT   P  Y + R    +      +++
Sbjct: 184 VIDYEDLRPLV-DIDAVKAFRNNALNPEHPVTRGTAENPDVYFQGREASNKYYNAIPELV 242

Query: 237 DEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMT 296
           +    E  K  GR+Y     Y  +DAE I + MGS++  +++ +D    +G KVG  K+ 
Sbjct: 243 ENYMGEISKITGREYHLFNYYGAEDAERIIIAMGSISDAIEETIDYLNAKGEKVGVLKVH 302

Query: 297 VYRPFPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLMLDFIAG 354
           ++RPF VE   + + K  K +A +++    G YG  ++ D   A       P+++    G
Sbjct: 303 LFRPFSVEHFFKYIPKTVKKIAVLDRTKEPGSYGEPLYLDVVTAFYQSDLNPVIVGGRYG 362

Query: 355 LGGRD 359
           LG +D
Sbjct: 363 LGSKD 367


>pir||A81294 pyruvate-flavodoxin oxidoreductase Cj1476c [imported] -
           Campylobacter jejuni (strain NCTC 11168)
           >gi|6968902|emb|CAB73898.1| (AL139078)
           pyruvate-flavodoxin oxidoreductase [Campylobacter
           jejuni]
           Length = 1186
           
 Score =  151 bits (377), Expect = 2e-35
 Identities = 118/393 (30%), Positives = 193/393 (49%), Gaps = 21/393 (5%)

Query: 3   IRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGE-----LDAEFIKVE 57
           I   M  NEAAA+AA  A  +V   +PITPS+ + +    + A G+     +  + ++++
Sbjct: 4   IMKTMDGNEAAAYAA-YAFTEVAGIYPITPSSPMADYTDMWAAAGKKNLFGVPVKIVEMQ 62

Query: 58  SEHSAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAP-IN 116
           SE  A  ++ G+  AG  T T TASQGL L    ++  AG  LP V+ +  R+L+A  ++
Sbjct: 63  SEAGAAGSVHGSLQAGALTTTYTASQGLLLKIPNMYKIAGQLLPCVIHVAARSLAAQALS 122

Query: 117 IWNDWQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTV 176
           I+ D QD  + R  G+    + + QE +DL  +A+  A   RV  P +  FD F  +H +
Sbjct: 123 IFGDHQDIYAARQIGFAMLCSHSVQETMDLAGVAHLAAIKGRV--PFLHFFDGFRTSHEI 180

Query: 177 EPVEIPDQEVVDEFLGE---YEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENAR 233
           + VE+ D    D  L      E ++  L+P+ P T+GT      Y + R +     +   
Sbjct: 181 QKVEVMDYAHFDRLLDREALLEFRNNALNPENPKTRGTAQNDDIYFQTREVSNRFYDALP 240

Query: 234 KVIDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAA 293
            V++E   E  K  GR+Y+    Y   + E + V MGS+   L++ VD    +G KVG  
Sbjct: 241 DVVNEYMQEISKITGREYKPFTYYGHKEPECVIVAMGSVTQALEEVVDYLNAKGEKVGIL 300

Query: 294 KMTVYRPFPVEEIRE-LAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLMLDF 351
           K+ +YRPF ++   + + K  K +A +++    G  G  ++ D  +A       P+++  
Sbjct: 301 KVYLYRPFSLKYFFDVMPKSVKKIAVLDRTKEPGSLGEPLYLDVKSAFYGRENAPVIVGG 360

Query: 352 IAGLGGRDVTFNQLDEALSIAKEALEKGKVEKP 384
             GL  +DV     D A  IA    E  K++ P
Sbjct: 361 RYGLSSKDV-----DPAQMIA--VFENLKLDNP 386


>sp|P19543|NIFJ_ENTAG PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|469077|emb|CAA55302.1|
           (X78558) nifJ [Pantoea agglomerans]
           >gi|1480137|emb|CAA68011.1| (X99694) nifJ [Enterobacter
           agglomerans]
           Length = 1173
           
 Score =  150 bits (374), Expect = 3e-35
 Identities = 107/365 (29%), Positives = 178/365 (48%), Gaps = 14/365 (3%)

Query: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELD-----AEFIKVESEHS 61
           M  N AAA+ +  A   V A +PITPST + E + E+ A G+ +      + ++++SE  
Sbjct: 8   MDGNTAAAYVS-YAFTDVTAIYPITPSTPMAESVDEWAAQGKKNLFGQTVKIMEMQSESG 66

Query: 62  AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWND 120
           A  A+ GA  AG    T TASQGL LM   ++  AG  LP V  +  RAL+   +NI+ D
Sbjct: 67  AAGAIHGALQAGALATTYTASQGLLLMTPNMYKIAGELLPAVFHVSARALATNSLNIFGD 126

Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180
            QD+ + R TG       + Q+ +DL  +A+  A   R+  P +  FD F  +H ++ +E
Sbjct: 127 HQDSYAVRHTGCAMLAESSVQQVMDLAAVAHLTAIKGRI--PFINFFDGFRTSHEIQKIE 184

Query: 181 IPDQEVVDEFLGE---YEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVID 237
           + D E +   L        +   L P  P+ +GT   P  Y + R    +      ++++
Sbjct: 185 VLDYEDLAHLLDRDAVARFRQNALHPDHPVVRGTAQNPDIYFQEREASNKFYMALPEMVE 244

Query: 238 EAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTV 297
              A+     GR+Y     Y   DA  + + MGS+  T+++ VD     G KVG   + +
Sbjct: 245 SYMAKISALTGREYHLFNYYGAPDAGRMIIAMGSVCETIQETVDYLNARGEKVGVLTVHL 304

Query: 298 YRPFPVEE-IRELAKKTKVLAFIEKDISMG-LYGAVFTDASAALINESEKPLMLDFIAGL 355
           YRPF ++   + + K    +A +++    G L   ++ D  +A  N   +P+++     L
Sbjct: 305 YRPFSLKHFFKYIPKSVSNIAVLDRTKEPGSLAEPLYLDVKSAFYNSDWRPVIVGGRYAL 364

Query: 356 GGRDV 360
           GG+D+
Sbjct: 365 GGKDI 369


>sp|P03833|NIFJ_KLEPN PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|43821|emb|CAA31665.1|
           (X13303) nifJ protein (AA 1-1171) [Klebsiella
           pneumoniae]
           Length = 1171
           
 Score =  148 bits (370), Expect = 1e-34
 Identities = 109/370 (29%), Positives = 176/370 (47%), Gaps = 14/370 (3%)

Query: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELD-----AEFIKVESEHS 61
           M  N AAAW +  A  +V A +PITPST + E + E+ A G+ +        ++++SE  
Sbjct: 8   MDGNAAAAWIS-YAFTEVAAIYPITPSTPMAENVDEWAAQGKKNLFGQPVRLMEMQSEAG 66

Query: 62  AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWND 120
           A  A+ GA  AG  T T TASQGL LM   ++  AG  LP V  +  RAL+   +NI+ D
Sbjct: 67  AAGAVHGALQAGALTTTYTASQGLLLMIPNMYKIAGELLPGVFHVSARALATNSLNIFGD 126

Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180
            QD ++ R TG       N Q+ +DL  +A+  A   R+  P +  FD F  +H ++ +E
Sbjct: 127 HQDVMAVRQTGCAMLAENNVQQVMDLSAVAHLAAIKGRI--PFVNFFDGFRTSHEIQKIE 184

Query: 181 IPDQEVVDEFLGE---YEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVID 237
           + + E +   L        +   L P  P+ +GT   P  Y + R       +    +++
Sbjct: 185 VLEYEQLATLLDRPALDSFRRNALHPDHPVIRGTAQNPDIYFQEREAGNRFYQALPDIVE 244

Query: 238 EAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTV 297
               +     GR+Y         DAE + + MGS+  T+++ VD     G KVG   + +
Sbjct: 245 SYMTQISALTGREYHLFNYTGAADAERVIIAMGSVCDTVQEVVDTLNAAGEKVGLLSVHL 304

Query: 298 YRPFPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLMLDFIAGL 355
           +RPF +     +L K  + +A +++    G     +  D   A  +  + PL++     L
Sbjct: 305 FRPFSLAHFFAQLPKTVQRIAVLDRTKEPGAQAEPLCLDVKNAFYHHDDAPLIVGGRYAL 364

Query: 356 GGRDVTFNQL 365
           GG+DV  N +
Sbjct: 365 GGKDVLPNDI 374


>pir||QQKBFP pyruvate (flavodoxin) dehydrogenase nifJ (EC 1.2.99.-) - Klebsiella
           pneumoniae >gi|43863|emb|CAA31501.1| (X13109)
           pyruvate-flavodoxin oxidoreductase [Klebsiella
           pneumoniae]
           Length = 1171
           
 Score =  148 bits (370), Expect = 1e-34
 Identities = 109/370 (29%), Positives = 176/370 (47%), Gaps = 14/370 (3%)

Query: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELD-----AEFIKVESEHS 61
           M  N AAAW +  A  +V A +PITPST + E + E+ A G+ +        ++++SE  
Sbjct: 8   MDGNAAAAWIS-YAFTEVAAIYPITPSTPMAENVDEWAAQGKKNLFGQPVRLMEMQSEAG 66

Query: 62  AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWND 120
           A  A+ GA  AG  T T TASQGL LM   ++  AG  LP V  +  RAL+   +NI+ D
Sbjct: 67  AAGAVHGALQAGALTTTYTASQGLLLMIPNMYKIAGELLPGVFHVSARALATNSLNIFGD 126

Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180
            QD ++ R TG       N Q+ +DL  +A+  A   R+  P +  FD F  +H ++ +E
Sbjct: 127 HQDVMAVRQTGCAMLAENNVQQVMDLSAVAHLAAIKGRI--PFVNFFDGFRTSHEIQKIE 184

Query: 181 IPDQEVVDEFLGE---YEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVID 237
           + + E +   L        +   L P  P+ +GT   P  Y + R       +    +++
Sbjct: 185 VLEYEQLATLLDRPALDSFRRNALHPDHPVIRGTAQNPDIYFQEREAGNRFYQALPDIVE 244

Query: 238 EAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTV 297
               +     GR+Y         DAE + + MGS+  T+++ VD     G KVG   + +
Sbjct: 245 SYMTQISALTGREYHLFNYTGAADAERVIIAMGSVCDTVQEVVDTLNAAGEKVGLLSVHL 304

Query: 298 YRPFPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLMLDFIAGL 355
           +RPF +     +L K  + +A +++    G     +  D   A  +  + PL++     L
Sbjct: 305 FRPFSLAHFFAQLPKTVQRIAVLDRTKEPGAQAEPLCLDVKNAFYHHDDAPLIVGGRYAL 364

Query: 356 GGRDVTFNQL 365
           GG+DV  N +
Sbjct: 365 GGKDVLPNDI 374


>pir||G71262 probable pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) TP0939 -
           syphilis spirochete >gi|3323259|gb|AAC65895.1|
           (AE001262) pyruvate oxidoreductase [Treponema pallidum]
           Length = 1184
           
 Score =  145 bits (363), Expect = 7e-34
 Identities = 112/376 (29%), Positives = 187/376 (48%), Gaps = 24/376 (6%)

Query: 6   VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELD-----AEFIKVESEH 60
           +M  N A    A  A  +VIA FPITPS+ + E   E+ A G  +        ++++SE 
Sbjct: 8   MMDGNTAVGHVAH-ALSEVIAIFPITPSSPMGEIADEYSARGRTNIWGTVPTVVELQSEA 66

Query: 61  SAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRAL-SAPINIWN 119
            A  A+ GA   G  + T TASQGL LM   ++  AG     V  +  RA+ ++ ++I+ 
Sbjct: 67  GASGAVHGALTTGALSSTFTASQGLLLMIPNMYKIAGELTSAVFHVAARAVATSSLSIFG 126

Query: 120 DWQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPV 179
           D QD ++ R TGW    + + QEA+D  ++A+    + RV  P +  FD F  +H ++ +
Sbjct: 127 DHQDVMACRQTGWALLASNSVQEAMDTAVIAHAATLEARV--PFVHFFDGFRTSHEIQKI 184

Query: 180 EIPDQEVVDEFLGEYEPKHAY----LDPKRPITQGTLAFPAHYMEARYLVWEAMENARKV 235
           E    +V+   + + E  HA+    L P++P+ +GT   P  Y + R  V      A  +
Sbjct: 185 EEVSYDVMRAMIDD-ELVHAHRMRGLTPEKPVVRGTAQNPDVYFQVRESVNRYYAVAPSI 243

Query: 236 IDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKM 295
           + +A   +    GR+Y+  + Y   DAE + V +GS +  +++ VD    +G K G  K+
Sbjct: 244 VQKAMDRYAALTGRQYRLFDYYGAPDAEKVIVMIGSGSEAVEETVDVLNAQGGKCGLVKV 303

Query: 296 TVYRPFPVE-EIRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALIN-ESEK------- 345
            +YRPF  E  +  L K  + +A +++    G  G  ++ D   A+   +S+K       
Sbjct: 304 RLYRPFSAECFVNALPKTVQAIAVLDRTKEPGSLGEPLYEDVRTAIGQMQSQKKCPFTHY 363

Query: 346 PLMLDFIAGLGGRDVT 361
           PL+L    GLG ++ T
Sbjct: 364 PLVLGGRYGLGSKEFT 379


>gb|AAC83148.1| (AF061850) putative pyruvate oxidoreductase; POR [Brachyspira
           pilosicoli]
           Length = 275
           
 Score =  143 bits (357), Expect = 3e-33
 Identities = 89/262 (33%), Positives = 133/262 (49%), Gaps = 6/262 (2%)

Query: 45  ANGELDAEFIKVESEHSAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVM 104
           ANG      I  + EH A     GA+ AG R F AT++ GL    E L + AG R P+V+
Sbjct: 3   ANGRHTVCMIPGDGEHGAAGICYGATTAGGRVFNATSANGLLFAMEQLPVQAGTRFPMVL 62

Query: 105 AIGNRALSAPINIWNDWQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAM 164
            + NR +S P++I  D  D +   +TGWI   A   Q   D  + A K+A  E+  LP +
Sbjct: 63  NVVNRTVSGPLDIKCDQSDIMMALNTGWIIIMAHTTQMVYDFNIFALKIA--EKAKLPII 120

Query: 165 VGFDAFILTHTVEPVEI-PDQEVVDEFLGEYEPKHAYLDP-KRPITQGTLAFPAHYMEAR 222
           V  D F  +H  + + +  + + V +FLG+Y P+   ++P K P+T G          ++
Sbjct: 121 VSSDGFFTSHQKKKIHLFKNDKDVQDFLGKYTPEVTSVEPTKNPVTIGPYMNEDELTGSK 180

Query: 223 YLVWEAMENARKVIDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSL--AGTLKDWV 280
             + +A+E++R +I E F EF    GRKY  IE +  + AE+  +  GS    GTL    
Sbjct: 181 LQLSQALEDSRAIIAEVFEEFASLSGRKYSPIETHNMEGAEVALMLCGSAYETGTLAVDE 240

Query: 281 DKKREEGYKVGAAKMTVYRPFP 302
            +K     K+GA  +T  RPFP
Sbjct: 241 MRKANPNLKIGAFAITQIRPFP 262


>emb|CAA70873.1| (Y09702) pyruvate-ferredoxin oxidoreductase [Desulfovibrio
           africanus]
           Length = 1232
           
 Score =  138 bits (345), Expect = 9e-32
 Identities = 109/364 (29%), Positives = 177/364 (47%), Gaps = 19/364 (5%)

Query: 10  NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDA-----EFIKVESEHSAIS 64
           N A A  A  A  +V A +PITPS+ + E+  ++ A G  +         +++SE  A  
Sbjct: 11  NTATAHVA-YAMSEVAAIYPITPSSTMGEEADDWAAQGRKNIFGQTLTIREMQSEAGAAG 69

Query: 65  ALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWNDWQD 123
           A+ GA AAG  T T TASQGL LM   ++  +G  LP V  +  RA++A  ++I+ D QD
Sbjct: 70  AVHGALAAGALTTTFTASQGLLLMIPNMYKISGELLPGVFHVTARAIAAHALSIFGDHQD 129

Query: 124 TISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPD 183
             + R TG+    + + QEA D+ L+A+  A +  V  P M  FD F  +H ++ +E+ D
Sbjct: 130 IYAARQTGFAMLASSSVQEAHDMALVAHLAAIESNV--PFMHFFDGFRTSHEIQKIEVLD 187

Query: 184 QE-----VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDE 238
                  V  + L E+  K   ++P+ P  +GT   P  Y + R            ++ E
Sbjct: 188 YADMASLVNQKALAEFRAKS--MNPEHPHVRGTAQNPDIYFQGREAANPYYLKVPGIVAE 245

Query: 239 AFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVY 298
              +     GR Y+  +     DAE + V+MGS   T+++ ++    +G K+G  K+ +Y
Sbjct: 246 YMQKVASLTGRSYKLFDYVGAPDAERVIVSMGSSCETIEEVINHLAAKGEKIGLIKVRLY 305

Query: 299 RPFPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESE-KPLMLDFIAGL 355
           RPF  E     L    KV+  +++    G  G  ++ D  +A +   E  P +L    GL
Sbjct: 306 RPFVSEAFFAALPASAKVITVLDRTKEPGAPGDPLYLDVCSAFVERGEAMPKILAGRYGL 365

Query: 356 GGRD 359
           G ++
Sbjct: 366 GSKE 369


>pdb|1B0P|A Chain A, Crystal Structure Of Pyruvate-Ferredoxin Oxidoreductase
           From Desulfovibrio Africanus >gi|4558092|pdb|1B0P|B
           Chain B, Crystal Structure Of Pyruvate-Ferredoxin
           Oxidoreductase From Desulfovibrio Africanus
           >gi|4558221|pdb|2PDA|A Chain A, Crystal Structure Of The
           Complex Between Pyruvate- Ferredoxin Oxidoreductase From
           Desulfovibrio Africanus And Pyruvate.
           >gi|4558222|pdb|2PDA|B Chain B, Crystal Structure Of The
           Complex Between Pyruvate- Ferredoxin Oxidoreductase From
           Desulfovibrio Africanus And Pyruvate
           Length = 1231
           
 Score =  138 bits (345), Expect = 9e-32
 Identities = 109/364 (29%), Positives = 177/364 (47%), Gaps = 19/364 (5%)

Query: 10  NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDA-----EFIKVESEHSAIS 64
           N A A  A  A  +V A +PITPS+ + E+  ++ A G  +         +++SE  A  
Sbjct: 10  NTATAHVA-YAMSEVAAIYPITPSSTMGEEADDWAAQGRKNIFGQTLTIREMQSEAGAAG 68

Query: 65  ALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWNDWQD 123
           A+ GA AAG  T T TASQGL LM   ++  +G  LP V  +  RA++A  ++I+ D QD
Sbjct: 69  AVHGALAAGALTTTFTASQGLLLMIPNMYKISGELLPGVFHVTARAIAAHALSIFGDHQD 128

Query: 124 TISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPD 183
             + R TG+    + + QEA D+ L+A+  A +  V  P M  FD F  +H ++ +E+ D
Sbjct: 129 IYAARQTGFAMLASSSVQEAHDMALVAHLAAIESNV--PFMHFFDGFRTSHEIQKIEVLD 186

Query: 184 QE-----VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDE 238
                  V  + L E+  K   ++P+ P  +GT   P  Y + R            ++ E
Sbjct: 187 YADMASLVNQKALAEFRAKS--MNPEHPHVRGTAQNPDIYFQGREAANPYYLKVPGIVAE 244

Query: 239 AFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVY 298
              +     GR Y+  +     DAE + V+MGS   T+++ ++    +G K+G  K+ +Y
Sbjct: 245 YMQKVASLTGRSYKLFDYVGAPDAERVIVSMGSSCETIEEVINHLAAKGEKIGLIKVRLY 304

Query: 299 RPFPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESE-KPLMLDFIAGL 355
           RPF  E     L    KV+  +++    G  G  ++ D  +A +   E  P +L    GL
Sbjct: 305 RPFVSEAFFAALPASAKVITVLDRTKEPGAPGDPLYLDVCSAFVERGEAMPKILAGRYGL 364

Query: 356 GGRD 359
           G ++
Sbjct: 365 GSKE 368


>emb|CAA57480.1| (X81893) nifJ [Enterobacter agglomerans]
           Length = 308
           
 Score =  138 bits (344), Expect = 1e-31
 Identities = 96/304 (31%), Positives = 150/304 (48%), Gaps = 12/304 (3%)

Query: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELD-----AEFIKVESEHS 61
           M  N AAA+ +  A   V A +PITPST + E + E+ A G+ +      + ++++SE  
Sbjct: 8   MDGNTAAAYVS-YAFTDVTAIYPITPSTPMAESVDEWAAQGKKNLFGQTVKVMEMQSESG 66

Query: 62  AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWND 120
           A  A+ GA  AG    T TASQGL LM   ++  AG  LP V  +  RAL+   +NI+ D
Sbjct: 67  AAGAIHGALQAGALATTYTASQGLLLMTPNMYKIAGELLPAVFHVSARALATNSLNIFGD 126

Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180
            QD ++ R TG       + Q+ +DL  +A+  A   R+  P +  FD F  +H ++ +E
Sbjct: 127 HQDVMAVRQTGCAMLAESSVQQVMDLAAVAHLTAIKGRI--PFINFFDGFRTSHEIQKIE 184

Query: 181 IPDQEVVDEFL---GEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVID 237
           + D E +   L        +   L P  P+ +GT   P  Y + R    +      ++++
Sbjct: 185 VLDYEELAALLDWDAVTRFRQNALHPDHPVVRGTAQNPDIYFQEREASNKFYMALPEMVE 244

Query: 238 EAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTV 297
              A+  K  GR+Y     Y   DA  + + MGS+  T+++ VD     G KVG   + +
Sbjct: 245 SYMAKISKLTGREYHLFNYYGAPDAGRMIIAMGSVCETIQETVDYLNASGEKVGVLTVHL 304

Query: 298 YRPF 301
           YRPF
Sbjct: 305 YRPF 308


>pir||C70403 ferredoxin oxidoreductase alpha subunit - Aquifex aeolicus
           >gi|2983644|gb|AAC07211.1| (AE000728) ferredoxin
           oxidoreductase alpha subunit [Aquifex aeolicus]
           Length = 404
           
 Score =  138 bits (344), Expect = 1e-31
 Identities = 97/337 (28%), Positives = 161/337 (46%), Gaps = 19/337 (5%)

Query: 10  NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISALVGA 69
           +EA   AAK A      ++PITP +     + E    G +   F + ESE   +S + G 
Sbjct: 39  SEAVKEAAKRASVDASISYPITPQSEAAHMLGELWREGYIGVYF-RGESEFGVMSEVAGC 97

Query: 70  SAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTISQRD 129
           + AG RT T T+  G     EV  + AG RLPI + +  R +++P++I  D  +     D
Sbjct: 98  AMAGARTITTTSGPGTMRAMEVFPMWAGSRLPIQLVLMARGINSPLSIQPDNLEISFLLD 157

Query: 130 TGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEVVDE 189
           TG + ++AE  QE  D+I+  + VAE   V +P +   D F ++HT E V +P +++   
Sbjct: 158 TGCMVWHAETAQELFDMIIAGFVVAEQPDVHVPIITAIDGFFISHTREAVYLPPEDIA-- 215

Query: 190 FLGEYEPKHAYLDP-KRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEKKFG 248
            L  Y P  A + P    +  G        M++ Y+ + A   + +    A  E  + + 
Sbjct: 216 -LPPYNPYKAPMPPIDMEMPPGRFMRDPFVMKSNYISY-ATHASWQFEVRAAIERSRPYA 273

Query: 249 RKYQK--IEEYRTDDAEIIFVTMGSLAGTLKDWVD-KKREEGYKVGAAKMTVYRPFPVEE 305
           + Y +  +E +   + E++F+  G+ A   K+       EEG K    ++   RPFP EE
Sbjct: 274 KHYLRGLVEHFGDPEGEVLFIASGTAAAQAKEATQILIHEEGIKARVLRLKTLRPFPTEE 333

Query: 306 IRELAKKTK--------VLAFIEKDISMGLYGAVFTD 334
           +RE  K  K        V+ ++E+++   LYG  +TD
Sbjct: 334 VREAVKGAKYIFIPEFNVVGWLEREVKRALYG--YTD 368


>dbj|BAA95605.1| (AB042412) pyruvate:ferredoxin oxidoreductase alpha subunit
           [Hydrogenobacter thermophilus]
           Length = 400
           
 Score =  138 bits (343), Expect = 1e-31
 Identities = 93/333 (27%), Positives = 156/333 (45%), Gaps = 14/333 (4%)

Query: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAL 66
           M  +EA   A K A      ++PITP +     I E    G +   F + ESE   +S +
Sbjct: 33  MTGSEAVKEAVKRASVDASVSYPITPQSEAAHLIGELWVEGYVGVYF-RGESEFGVMSEI 91

Query: 67  VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTIS 126
            G + AG RT T T+  G     E   + AG R+P+ + +  R ++AP++I  D  +   
Sbjct: 92  AGCALAGARTITTTSGPGTLRAMENFPMWAGTRIPVQLVLMARGVNAPLSIQPDNLEVSF 151

Query: 127 QRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEV 186
             DTG + +YAE  Q+  D+IL  + VAE   V +P +   D F ++HT E V +P  ++
Sbjct: 152 LLDTGCMIWYAETAQDLFDMILAGFVVAEQPDVHVPVITVVDGFFVSHTRETVMLPPDDI 211

Query: 187 VDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEKK 246
                  Y      +D + P   G        M++ Y+ +    + +  +  A  E  + 
Sbjct: 212 ALPPYNPYRAPMPVIDAEVP--PGRFLRDPFVMKSNYISYATHASWQWEV-RAAIERSRP 268

Query: 247 FGRKYQK--IEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVE 304
           + + Y +  IE +   +A+++FV  G+ +   K+ V    +EG      K+   RPFP+E
Sbjct: 269 YAKHYLRGLIEHFGDPEADLVFVACGTASAQAKEAVRMLEDEGISARVVKLKTIRPFPIE 328

Query: 305 EIRELAKKTK--------VLAFIEKDISMGLYG 329
           E+RE  K  K        V+ ++E+++   LYG
Sbjct: 329 ELREATKGAKYIFVPEFNVVGWLEREVRRYLYG 361


>sp|P52647|NIFJ_ECOLI PROBABLE PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|7431614|pir||E64888
           probable pyruvate (flavodoxin) dehydrogenase (EC
           1.2.99.-) ydbK - Escherichia coli
           >gi|1742250|dbj|BAA14982.1| (D90775) Pyruvate-flavodoxin
           oxidoreductase (EC 1.-.-.-). [Escherichia coli]
           >gi|1742256|dbj|BAA14987.1| (D90776) Pyruvate-flavodoxin
           oxidoreductase (EC 1.-.-.-). [Escherichia coli]
           >gi|1787642|gb|AAC74460.1| (AE000234) putative
           oxidoreductase, Fe-S subunit [Escherichia coli K12]
           Length = 1174
           
 Score =  134 bits (335), Expect = 1e-30
 Identities = 101/350 (28%), Positives = 167/350 (46%), Gaps = 18/350 (5%)

Query: 23  KVIAAFPITPSTLVPEKISEFVANGELDA-----EFIKVESEHSAISALVGASAAGVRTF 77
           +VIA +PITPS+ + E+   +  NG  +        ++++SE  AI+ + GA   G  + 
Sbjct: 19  EVIAIYPITPSSTMAEQADAWAGNGLKNVWGDTPRVVEMQSEAGAIATVHGALQTGALST 78

Query: 78  TATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWNDWQDTISQRDTGWIQFY 136
           + T+SQGL LM   L+  AG   P V+ +  R ++   ++I+ D  D ++ R TG     
Sbjct: 79  SFTSSQGLLLMIPTLYKLAGELTPFVLHVAARTVATHALSIFGDHSDVMAVRQTGCAMLC 138

Query: 137 AENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEVVDEFLGEYE- 195
           A N QEA D  L++       RV  P +  FD F  +H +  +     + + + + + E 
Sbjct: 139 AANVQEAQDFALISQIATLKSRV--PFIHFFDGFRTSHEINKIVPLADDTILDLMPQVEI 196

Query: 196 --PKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEKKFGRKYQK 253
              +   L+P+ P+ +GT A P  Y ++R             +++A  +F    GR+YQ 
Sbjct: 197 DAHRARALNPEHPVIRGTSANPDTYFQSREATNPWYNAVYDHVEQAMNDFSAATGRQYQP 256

Query: 254 IEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVEE-IRELAKK 312
            E Y    AE + + MGS  GT ++ VD+    G KVG  K+ +YRPF  +  ++ L   
Sbjct: 257 FEYYGHPQAERVIILMGSAIGTCEEVVDELLTRGEKVGVLKVRLYRPFSAKHLLQALPGS 316

Query: 313 TKVLAFIEKDISMG-----LYGAVFTDASAALINESEKPLMLDFIAGLGG 357
            + +A +++    G     LY  V T A A   N  E+  +   I G  G
Sbjct: 317 VRSVAVLDRTKEPGAQAEPLYLDVMT-ALAEAFNNGERETLPRVIGGRYG 365


>sp|P52965|NIFJ_SYNY3 PUTATIVE PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|7431613|pir||S77082
           pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) nifJ -
           Synechocystis sp. (strain PCC 6803)
           >gi|1006618|dbj|BAA10774.1| (D64005) pyruvate
           oxidoreductase [Synechocystis sp.]
           Length = 1199
           
 Score =  134 bits (334), Expect = 2e-30
 Identities = 108/372 (29%), Positives = 179/372 (48%), Gaps = 14/372 (3%)

Query: 1   MPIRTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAE-----FIK 55
           +P    +  NEA A  A L   +VIA +PITPS+ + E    + A    +        ++
Sbjct: 3   LPTYATLDGNEAVARVAYLLS-EVIAIYPITPSSPMGEWSDAWAAEHRPNLWGTVPLVVE 61

Query: 56  VESEHSAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAP- 114
           ++SE  A   + GA  +G  T T TASQGL LM   +   AG    +V+ +  R+L+A  
Sbjct: 62  MQSEGGAAGTVHGALQSGALTTTFTASQGLMLMLPNMHKIAGELTAMVLHVAARSLAAQG 121

Query: 115 INIWNDWQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTH 174
           ++I+ D  D ++ R+TG+    + + QEA D  L+A   +   R+  P +  FD F  +H
Sbjct: 122 LSIFGDHSDVMAARNTGFAMLSSNSVQEAHDFALIATATSFATRI--PGLHFFDGFRTSH 179

Query: 175 TVEPVEIPDQEVVDEFLGEYEP---KHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMEN 231
             + +E+  QEV+   + + +    +   L P RP  +GT   P  Y +AR  V     +
Sbjct: 180 EEQKIELLPQEVLRGLIKDEDVLAHRGRALTPDRPKLRGTAQNPDVYFQARETVNPFYAS 239

Query: 232 ARKVIDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVG 291
              V+++   +F +  GR Y+  E     +AE + V MGS A T ++ VD    +G KVG
Sbjct: 240 YPNVLEQVMEQFGQLTGRHYRPYEYCGHPEAERVIVLMGSGAETAQETVDFLTAQGEKVG 299

Query: 292 AAKMTVYRPFPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLML 349
             K+ +YRPF  +  +  L K  + +A +++    G  G  ++ D   A       P ++
Sbjct: 300 LLKVRLYRPFAGDRLVNALPKTVQKIAVLDRCKEPGSIGEPLYQDVLTAFFEAGMMPKII 359

Query: 350 DFIAGLGGRDVT 361
               GL  ++ T
Sbjct: 360 GGRYGLSSKEFT 371


>emb|CAB43934.1| (Y17727) pyruvate ferredoxin oxidoreductase [Clostridium
           pasteurianum]
           Length = 1181
           
 Score =  133 bits (332), Expect = 3e-30
 Identities = 105/366 (28%), Positives = 177/366 (47%), Gaps = 17/366 (4%)

Query: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELD-----AEFIKVESEHS 61
           M  N AAA  A  A   V   +PITPS+ + + +  + A G+ +      + ++++SE  
Sbjct: 8   MDGNTAAAHVA-YAYTDVAGIYPITPSSPMADSVDMWSAAGQENIFGNQVKVVEMQSEAG 66

Query: 62  AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWND 120
           A   + G+ AAG  T T TASQGL LM   ++  AG  LP V  +  R +++  +NI+ D
Sbjct: 67  AAGTVHGSLAAGALTTTFTASQGLLLMIPNMYKIAGEMLPSVFHVSARTVASHALNIFGD 126

Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180
             D  + R  G+      N QE +DL  +A+  A + +V  P +  FD F  +H ++ +E
Sbjct: 127 HSDVYACRQVGFAMLAETNPQEVMDLSPVAHLAALEGKV--PFINFFDGFRTSHEIQKIE 184

Query: 181 IPDQEVVDEFLGEYEPK----HAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVI 236
             D E + E       K    HA L+P++P  +G+      + + R     A  N   ++
Sbjct: 185 KWDYEDLKEMCNMDAVKAFRDHA-LNPEKPAMRGSHENGDVFFQHREACNTAYNNLPAIV 243

Query: 237 DEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMT 296
           ++  A+  +K G  Y     Y  +DA+ + + MGS+    ++ +D    +G KVG  K+ 
Sbjct: 244 EKYMAKVNEKLGTDYDLFNYYGAEDADRVIIAMGSICDVAEEVIDYLTAKGEKVGLVKVR 303

Query: 297 VYRPFPVEEI-RELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLMLDF-IA 353
           +YRP+  E I + L K  K +A +++    G  G  ++ D +  L       ++L     
Sbjct: 304 LYRPWVSESILKALPKTAKKVAVLDRTKEPGALGDPLYLDVATTLREAGLNDIILTAGRY 363

Query: 354 GLGGRD 359
           GLG +D
Sbjct: 364 GLGSKD 369


>pir||F82447 pyruvate-flavoredoxin oxidoreductase VCA0530 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9657937|gb|AAF96433.1| (AE004384)
           pyruvate-flavoredoxin oxidoreductase [Vibrio cholerae]
           Length = 1079
           
 Score =  130 bits (323), Expect = 3e-29
 Identities = 100/359 (27%), Positives = 172/359 (47%), Gaps = 22/359 (6%)

Query: 6   VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDA-----EFIKVESEH 60
           +  AN A A  A     +V+A +PITPST + E   ++ +  + +      + ++++SE 
Sbjct: 4   ITDANTAVARVAYQLS-EVLAVYPITPSTSMAESCEQWASQQKSNLLGDVPKLVEMQSEA 62

Query: 61  SAISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWN 119
            +I+ + GA+ +G    T T+SQGL LM   L+  AG   P V+ +  R ++   ++I+ 
Sbjct: 63  GSIAVVHGAAMSGALATTFTSSQGLLLMIPSLYKLAGELTPCVIHVAARTVATHALSIYC 122

Query: 120 DWQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPV 179
           D  D ++ R TG     A N QEA DL  +A   A   R  LP +  FD F+ +H +  +
Sbjct: 123 DHSDVMAIRQTGVAMLCASNAQEAQDLAAIATFSALQCR--LPFVHFFDGFLTSHAITQI 180

Query: 180 EIPDQEVVDEFLGEYEPKHAYLD-------PKRPITQGTLAFPAHYMEARYLVWEAMENA 232
           E   +E +   L    P  A +D       P RP  +G  A P  Y + R       ++ 
Sbjct: 181 EPLSEEALSALL----PMPALVDFRTRVLTPDRPTLRGATADPDSYFQCREAQTPYHQST 236

Query: 233 RKVIDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGA 292
            + +      FE + GR+YQ  E      A+ + V MGS   T+K  V    ++G ++G 
Sbjct: 237 PEQVQNIMDCFETQTGRRYQLAEYIGHPQAQSVIVAMGSSVDTIKQVVLAGVQQGERIGV 296

Query: 293 AKMTVYRPFPVEEIRELAKKTKV-LAFIEKDISMGLYG-AVFTDASAALINESEKPLML 349
            ++ +YRPFP + +R+    T   ++ +++    G +G  ++ D  +AL  +    + L
Sbjct: 297 IQIRLYRPFPSQALRDALPATVTHISVLDRTKEPGSHGEPLYLDVLSALYTQRANSIRL 355


>pir||B70400 ferredoxin oxidoreductase alpha subunit - Aquifex aeolicus
           >gi|2983615|gb|AAC07184.1| (AE000726) ferredoxin
           oxidoreductase alpha subunit [Aquifex aeolicus]
           Length = 389
           
 Score =  129 bits (322), Expect = 4e-29
 Identities = 103/378 (27%), Positives = 166/378 (43%), Gaps = 32/378 (8%)

Query: 10  NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISALVGA 69
           ++A A A K A   V  A+PITP +     + +  A G +  ++ + E E+ A+SA+ GA
Sbjct: 26  SQAFAEAVKRANVDVAIAYPITPQSETMHLVGDLYAQGYVK-DYYRAEEEYGAMSAIAGA 84

Query: 70  SAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTISQRD 129
              G R FTAT+  GL    E +    G R+P V+ +  R ++AP++I  D  +     +
Sbjct: 85  VRGGARAFTATSGPGLLRGLEAIVSWPGHRIPAVLGVMTRVVNAPLSIQPDNVEISYLLN 144

Query: 130 TGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEVV-- 187
           +G +  +AEN Q+  D  L  + ++E   V LP +V  + F +TH    VE+P +++   
Sbjct: 145 SGLVVLHAENQQDVFDFTLAGFVISEKVDVYLPVVVATEGFFVTHAKGYVELPPEDMKLP 204

Query: 188 --DEFLGEYEPKHAYLDPKR-----PITQGTLAFPAHYMEARYLVWEAMENARKVIDEAF 240
             D +     P    + P R     P+ +        +   +  VW A   A K I    
Sbjct: 205 PRDPYKAPVPPTDCEIPPARIQRDAPVQKSNFMSYLIHAVWQQEVWSANRRAAKWIKHYL 264

Query: 241 AEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300
                        + E    DAE+  V  G  A   ++       EG  VG  K+   RP
Sbjct: 265 G-----------GLIEVVNPDAEVFVVASGCAAAQGREAQRYATMEGLNVGLIKVKSLRP 313

Query: 301 FPVEEIRELAKKTKVLAFIEKDISMGLYGAVFTDASAALINESEKPLMLDFIAGLGGR-- 358
           FPV+EIRE  K  K +   E +I     G +  +  AA+ N     +++D     GG   
Sbjct: 314 FPVDEIREALKNAKAVIVPEHNI----VGWLAKEVKAAIPNSG---IVVDGPRVYGGMTL 366

Query: 359 --DVTFNQLDEALSIAKE 374
             ++   ++ +A  I KE
Sbjct: 367 PVELIMEEIYKAFGIKKE 384


>sp|Q06879|NIFJ_ANASP PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|2126544|pir||I39613 pyruvate
           (flavodoxin) dehydrogenase nifJ (EC 1.2.99.-) - Anabaena
           sp >gi|289139|gb|AAC36818.1| (L14925) nitrogen fixation
           protein [Anabaena sp.]
           Length = 1197
           
 Score =  123 bits (307), Expect = 2e-27
 Identities = 104/359 (28%), Positives = 173/359 (47%), Gaps = 29/359 (8%)

Query: 10  NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDA-----EFIKVESEHSAIS 64
           NEA A  A     +VIA +PITPS+ + E    ++A G  +        ++++SE  A  
Sbjct: 11  NEAVARVAYKLN-EVIAIYPITPSSAMGEWADAWMAEGRPNLWGTVPSVVQMQSEGGAAG 69

Query: 65  ALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWNDWQD 123
           A+ GA   G  + T TASQGL LM   L+   G    +V+ +  R+L+   ++I+ D  D
Sbjct: 70  AVHGALQTGSLSTTFTASQGLLLMIPNLYKIGGELTSMVVHVAARSLATHALSIFGDHSD 129

Query: 124 TISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPD 183
            ++ R TG+    + + QE+ D  L+A+    D RV    +  FD F  +H V+ VE+  
Sbjct: 130 VMAARGTGFAMLCSASVQESHDFALIAHAATLDTRVSF--LHFFDGFRTSHEVQKVELLA 187

Query: 184 QEVVDEFLGE---YEPKHAYLDPKRPITQGTLAFPAHYMEAR------YLVWEAMENARK 234
            + V   + E   +  +   L P  P+ +GT   P  + +AR      Y    A+   + 
Sbjct: 188 DDDVRSLINEDKIFAHRARALTPDSPLLRGTAQNPDVFFQAREGANPYYNACPAI--VQG 245

Query: 235 VIDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAK 294
           ++D+ F E   + GR YQ  E +   DA+ + + MGS   T+ + VD     G KVG  K
Sbjct: 246 IMDKFFGE---RTGRYYQIYEYHGASDADRLIIIMGSGCETVHETVDYLNARGEKVGVLK 302

Query: 295 MTVYRPFPVEE-IRELAKKTKVLAFIEKDISMG-----LYGAVFTDASAALINESEKPL 347
           + ++RP+ VE  ++ L    + +A +++    G     LY  V T      +N++  P+
Sbjct: 303 VRLFRPWDVERFVQALPHSVQAIAVLDRTKEPGSAGEPLYQDVVTAIHEGWVNKNNSPV 361


>gb|AAD55754.1|AF132546_1 (AF132546) pyruvate:ferredoxin oxidoreductase [Spironucleus
           barkhanus]
           Length = 1182
           
 Score =  119 bits (296), Expect = 5e-26
 Identities = 89/289 (30%), Positives = 145/289 (49%), Gaps = 13/289 (4%)

Query: 28  FPITPSTLVPEKISEFVANGELDA-----EFIKVESEHSAISALVGASAAGVRTFTATAS 82
           FPI+PS+ + E + E+ + G L+A        ++  E  A  AL GA   G  + T TAS
Sbjct: 21  FPISPSSPMAELVDEWASKGRLNAFDQVHRVTELNHEGGAAGALHGALLNGSLSSTYTAS 80

Query: 83  QGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWNDWQDTISQRDTGWIQFYAENNQ 141
           QGL LM   L+  A   LP V+ +  R ++   ++I  D  D ++ + TG     + + Q
Sbjct: 81  QGLLLMIPNLYKMAAEHLPGVLHVAARTIATHSLSIHGDHSDIMAIKQTGISILVSPDVQ 140

Query: 142 EALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEVVDEFLGEYEP----K 197
           EA+D  L+A+  A +     P +  FD +  +HT++ VE+   + +  F+  YE     +
Sbjct: 141 EAMDFALVAHIAAINADT--PFIHAFDGYRTSHTIKKVEVISYDKIKPFV-PYEKIAEFR 197

Query: 198 HAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEKKFGRKYQKIEEY 257
           H  L+ +RP   G+   P  +M+++              ++AF   EK  GRKY+ I+ +
Sbjct: 198 HKSLNSQRPEAYGSCMGPPVWMQSQEADNLHYSKILGHFEDAFVTVEKITGRKYEVIQYH 257

Query: 258 RTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVEEI 306
              DA  + V MGS   T+++ VD    +G KVGA  + ++RPFP   I
Sbjct: 258 GCADATDVIVIMGSGCITVRETVDYLNAQGRKVGAIFINLFRPFPSAHI 306


>dbj|BAB12024.1| (AB021127) pyruvate:NADP+ oxidoreductase [Euglena gracilis]
           Length = 1803
           
 Score =  115 bits (286), Expect = 7e-25
 Identities = 98/345 (28%), Positives = 165/345 (47%), Gaps = 15/345 (4%)

Query: 28  FPITPSTLVPEKISEFVANGELDA-----EFIKVESEHSAISALVGASAAGVRTFTATAS 82
           +PITPS+++ E    ++A G  +A     +  +++SE  A  AL GA AAG    T TAS
Sbjct: 92  YPITPSSVMGELADVWMAQGRKNAFGQVVDVREMQSEAGAAGALHGALAAGAIATTFTAS 151

Query: 83  QGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWNDWQDTISQRDTGWIQFYAENNQ 141
           QGL LM   ++  AG  +P V+ +  R L+   ++I+    D ++ R TGW    +   Q
Sbjct: 152 QGLLLMIPNMYKIAGELMPSVIHVAARELAGHALSIFGGHADVMAVRQTGWAMLCSHTVQ 211

Query: 142 EALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEVVDEFL--GEYEPKHA 199
           ++ D+ L+++       +  P +  FD F  +H V  +++     + + +  G  E   A
Sbjct: 212 QSHDMALISHVATLKSSI--PFVHFFDGFRTSHEVNKIKMLPYAELKKLVPPGTMEQHWA 269

Query: 200 Y-LDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEKKFGRKYQKIEEYR 258
             L+P  P  +GT      Y +      +   +  +V+ E   E     GR Y+  E   
Sbjct: 270 RSLNPMHPTIRGTNQSADIYFQNMESANQYYTDLAEVVQETMDEVAPYIGRHYKIFEYVG 329

Query: 259 TDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVEEIRELAKKT-KVLA 317
             DAE + V MGS A T+ + VD   + G KVGA  + +YRP+  +   ++  KT K +A
Sbjct: 330 APDAEEVTVLMGSGATTVNEAVDLLVKRGKKVGAVLVHLYRPWSTKAFEKVLPKTVKRIA 389

Query: 318 FIEKDISMGLYG-AVFTDASAA--LINESEKPLMLDFIAGLGGRD 359
            +++   +   G  ++ D SA   L  E +   ++    GLG +D
Sbjct: 390 ALDRCKEVTALGEPLYLDVSATLNLFPERQNVKVIGGRYGLGSKD 434


>gb|AAB49653.1| (U30149) pyruvate:ferredoxin oxidoreductase [Entamoeba histolytica]
           Length = 1162
           
 Score =  115 bits (285), Expect = 9e-25
 Identities = 100/386 (25%), Positives = 176/386 (44%), Gaps = 21/386 (5%)

Query: 10  NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDA-----EFIKVESEHSAIS 64
           N+AAA+ +  A   V   FPITPS+ + E    + + G  +      +  ++ESE  A  
Sbjct: 7   NQAAAYVS-YALSDVSFIFPITPSSPMAENADVWSSQGRKNVFGQVVDVYEMESEAGASG 65

Query: 65  ALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAP-INIWNDWQD 123
           A+ G  AAG    T T SQGL LM   +   AG  LP V  +  RAL+   ++I+ D  D
Sbjct: 66  AVHGGCAAGSLVSTYTCSQGLMLMIPNMIKIAGEHLPCVFHVTARALAGQALSIFGDHSD 125

Query: 124 TISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPD 183
            ++ R TG+    + N Q+  DL ++A+    +    LP M  FD F  +H ++ +    
Sbjct: 126 VMACRSTGFCLLSSHNVQQCHDLAIVAHLATLEAS--LPFMHFFDGFRTSHEIQKIHQLT 183

Query: 184 QEVVDEFLGEYEPKHAY---LDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAF 240
            + +   +       A+   L+P  P  +GT   P  + +A            +++ +  
Sbjct: 184 YDQIKSLVDMKYVDRAHKRGLNPIHPSQRGTSQGPDVFFQAVEKSNADYLKVPEIVQKYM 243

Query: 241 AEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRP 300
            +  +  GR Y+  E Y   DAE + V MG+    L++ VD   + G KVG   + +YRP
Sbjct: 244 DKVGELTGRHYKIFEYYGAADAERVVVVMGAAVPVLEECVDYLMKSGEKVGVLSVHLYRP 303

Query: 301 FPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLMLDFIAGLGGR 358
           +  +  + +L      ++ +++    G +G  ++ D +  L++  +    +    GLG +
Sbjct: 304 WSAKHFLEQLPNTVTKISVLDRTKEAGSFGEPLYLDVATTLLDAGKHIKCVGGRYGLGSK 363

Query: 359 DVTFNQLDEALSIAKEALEKGKVEKP 384
           + T        ++AK   +  K E+P
Sbjct: 364 EFT-------PAMAKAVFDNLKNEEP 382


>sp|Q53046|NIFJ_RHORU PYRUVATE-FLAVODOXIN OXIDOREDUCTASE >gi|628896|pir||S41961 pyruvate
           oxidoreductase - Rhodospirillum rubrum
           >gi|453436|emb|CAA54651.1| (X77515) pyruvate
           oxidoreductase [Rhodospirillum rubrum]
           Length = 1191
           
 Score =  113 bits (280), Expect = 4e-24
 Identities = 101/363 (27%), Positives = 165/363 (44%), Gaps = 18/363 (4%)

Query: 10  NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDA-----EFIKVESEHSAIS 64
           NEA A  A     +V   +PITPS+ + E   E+ A G  +      + ++++SE  A  
Sbjct: 12  NEACASVAYRVS-EVAVIYPITPSSTMGELSDEWSAKGLTNIWGAVPQVVEMQSEGGAAG 70

Query: 65  ALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWNDWQD 123
           A  GA   G    T TASQGL LM   ++  AG   P  M +  R L+   ++I+ D  D
Sbjct: 71  ACHGAIQTGSLGTTFTASQGLLLMIPNMYKIAGELTPFCMHVTARTLATHALSIFGDQSD 130

Query: 124 TISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPD 183
            ++ R TG+    + + QEA DL  +A+  + + R+  P +  FD F  +H V  +E+  
Sbjct: 131 VMACRQTGFAILASASVQEAHDLASVAHGASLESRI--PFLHFFDGFRTSHEVNKIELMT 188

Query: 184 QE----VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEA 239
            +    ++D+ L       A L P  P+T+GT   P  + +A+       +    ++   
Sbjct: 189 DDDLHAMIDDDLVAAHRARA-LTPDTPVTRGTAQNPDTFFQAQEARNPFYDACPAIVQSY 247

Query: 240 FAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYR 299
                   GR+Y   +      AE + V MGS A T+ + VD     G K+G  K+ ++R
Sbjct: 248 MDRLAALTGRRYGLFDYVGHPQAERVVVIMGSGAETVAETVDWLVARGEKIGVVKVRLFR 307

Query: 300 PFPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLMLDFI--AGL 355
           PF V+  +  L    + +A +++    G  G  ++ D   AL       L    +  A +
Sbjct: 308 PFSVDAFVAALPVSVRAIAVLDRCKESGAIGEPLYLDVVGALARAKALGLRAGIVDPAVI 367

Query: 356 GGR 358
           GGR
Sbjct: 368 GGR 370


>pir||S70963 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) - Rhodospirillum
           rubrum
           Length = 1191
           
 Score =  113 bits (280), Expect = 4e-24
 Identities = 101/363 (27%), Positives = 165/363 (44%), Gaps = 18/363 (4%)

Query: 10  NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDA-----EFIKVESEHSAIS 64
           NEA A  A     +V   +PITPS+ + E   E+ A G  +      + ++++SE  A  
Sbjct: 12  NEACASVAYRVS-EVAVIYPITPSSTMGELSDEWSAKGLTNIWGAVPQVVEMQSEGGAAG 70

Query: 65  ALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWNDWQD 123
           A  GA   G    T TASQGL LM   ++  AG   P  M +  R L+   ++I+ D  D
Sbjct: 71  ACHGAIQTGSLGTTFTASQGLLLMIPNMYKIAGELTPFCMHVTARTLATHALSIFGDQSD 130

Query: 124 TISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPD 183
            ++ R TG+    + + QEA DL  +A+  + + R+  P +  FD F  +H V  +E+  
Sbjct: 131 VMACRQTGFAILASASVQEAHDLASVAHGASLESRI--PFLHFFDGFRTSHEVNKIELMT 188

Query: 184 QE----VVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEA 239
            +    ++D+ L       A L P  P+T+GT   P  + +A+       +    ++   
Sbjct: 189 DDDLHAMIDDDLVAAHRARA-LTPDTPVTRGTAQNPDTFFQAQEARNPFYDACPAIVQSY 247

Query: 240 FAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYR 299
                   GR+Y   +      AE + V MGS A T+ + VD     G K+G  K+ ++R
Sbjct: 248 MDRLAALTGRRYGLFDYVGHPQAERVVVIMGSGAETVAETVDWLVARGEKIGVVKVRLFR 307

Query: 300 PFPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLMLDFI--AGL 355
           PF V+  +  L    + +A +++    G  G  ++ D   AL       L    +  A +
Sbjct: 308 PFSVDAFVAALPVSVRAIAVLDRCKESGAIGEPLYLDVVGALARAKALGLRAGIVDPAVI 367

Query: 356 GGR 358
           GGR
Sbjct: 368 GGR 370


>pir||H72214 hypothetical protein TM1759 - Thermotoga maritima (strain MSB8)
           >gi|4982338|gb|AAD36824.1|AE001814_6 (AE001814)
           2-oxoisovalerate oxidoreductase, beta subunit, putative
           [Thermotoga maritima]
           Length = 356
           
 Score =  112 bits (277), Expect = 8e-24
 Identities = 100/343 (29%), Positives = 155/343 (45%), Gaps = 36/343 (10%)

Query: 4   RTVMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANG--ELDAEFIKVESEHS 61
           + +MK NEA A +A  A  ++  A+PITP +    +I+E++A    E+   F++ ESE +
Sbjct: 6   KLMMKGNEAIAESAIRAGCRLYFAYPITPQS----EIAEYMARRLPEVGGVFLQTESEIA 61

Query: 62  AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDW 121
            ++ + GA+  G R  T+T+S G +LM E +   AG  LP V     R      NI    
Sbjct: 62  TVNMVYGAACTGKRVMTSTSSPGFSLMQEGISYIAGAELPCVFVDVVRGGPGLGNIQPSQ 121

Query: 122 QDTIS------QRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHT 175
            D           D   I       QEA+DL  LA+ +A+  R   P ++  D  I    
Sbjct: 122 GDYFQAVKGGGHGDYRLIVLAPSTLQEAVDLTQLAFDLAD--RYRNPVLILADGMI-GQM 178

Query: 176 VEPVEIPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKV 235
           +EPVE+P+   +        P H+         +G      H + A  +    +E   K 
Sbjct: 179 MEPVELPEMRDLSTL-----PDHSDW-----ALRGARNREPHRIAAFNIDPVGLEKMNKR 228

Query: 236 IDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKM 295
           + E +   E       Q+ EEYR D AE + V  G++   LK  VD  REEG   G  + 
Sbjct: 229 LQEKYRLIEAS----EQRWEEYRVDGAEYLMVGYGTMGRILKSVVDSLREEGIPAGLFRP 284

Query: 296 TVYRPFPVEEIRELAKKTKVLAFIE-------KDISMGLYGAV 331
               PFP   ++ELAKK +++  +E       +D+ + + G V
Sbjct: 285 VTLWPFPKRRLKELAKKVQLIFVVEMSSGQMVEDVQISVEGKV 327


>pir||T43259 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) pfoB precursor,
           hydrogenosomal - Trichomonas vaginalis
           >gi|622960|gb|AAA85495.1| (U16823) pyruvate:ferredoxin
           oxidoreductase proprotein [Trichomonas vaginalis]
           Length = 1157
           
 Score =  111 bits (276), Expect = 1e-23
 Identities = 97/335 (28%), Positives = 156/335 (45%), Gaps = 33/335 (9%)

Query: 28  FPITPSTLVPEKISEFVANGELDAEFIKV-----ESEHSAISALVGASAAGVRTFTATAS 82
           +PITP+T + E +  ++A G  +    KV     +SE  A +A+ GA+A G    T TAS
Sbjct: 31  YPITPATTMGELVDAWIAQGRKNIWGNKVNMAMMQSEGGAAAAVHGATAVGALCATFTAS 90

Query: 83  QGLALMHEVLFIAAGMRLPIVMAIGNRAL-SAPINIWNDWQDTISQRDTGWIQFYAENNQ 141
           QG  LM   ++   G   P V  I  R + ++ ++I+ND  D  + R TG    ++   Q
Sbjct: 91  QGALLMIPDMYKIVGEMCPAVFHIAARCIATSALSIYNDHGDIYACRATGMPILFSNGVQ 150

Query: 142 EALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEVV-----DEFLGEYEP 196
           EA DL  +A+  +      LP +  FD F  +H +   E  D E +      + L  +  
Sbjct: 151 EAHDLAAVAHLTS--IHTGLPFIHTFDGFRTSHEINTYEELDNETLWPLIDQKALAAFRA 208

Query: 197 KHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEK-------KFGR 249
           +   L+P+ P  +GT+  P +       VW+  E  RK      AE EK       K GR
Sbjct: 209 RS--LNPEHPSERGTICGPEY-------VWQMHEKLRKPYQALPAEVEKMMKALGDKTGR 259

Query: 250 KYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVEEIR-E 308
            Y+  +     D E + + MGS    +++++ +  E  YK G  K+ +YRPF VE     
Sbjct: 260 YYKPYQYAGPRDPENVIIMMGSGCDPVEEFITEHPE--YKTGLIKVYLYRPFSVEMFNAA 317

Query: 309 LAKKTKVLAFIEKDIS-MGLYGAVFTDASAALINE 342
           +    K +  ++K +   G    +F D +AA+I +
Sbjct: 318 IPSSVKRVCVLDKVVDPTGPREPLFEDVAAAIIGQ 352


>pir||S58236 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) - Entamoeba
           histolytica >gi|929587|emb|CAA90575.1| (Z50193) pyruvate
           oxidoreductase [Entamoeba histolytica]
           Length = 1165
           
 Score =  109 bits (271), Expect = 4e-23
 Identities = 102/391 (26%), Positives = 181/391 (46%), Gaps = 28/391 (7%)

Query: 10  NEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDA-----EFIKVESEHSAIS 64
           N+AAA+ +  A   V   FPITPS+ + E    + + G  +      +  ++ESE  A  
Sbjct: 7   NQAAAYVS-YALSDVSFIFPITPSSPMAENADVWSSQGRKNVFGQVVDVYEMESEAGASG 65

Query: 65  ALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALS-APINIWNDWQD 123
           A+ G  AAG    T T SQGL LM   +   AG  LP V  +  RAL+   ++I+ D  D
Sbjct: 66  AVHGGCAAGSLVSTYTCSQGLMLMIPNMIKIAGEHLPCVFHVTARALAEQALSIFGDHSD 125

Query: 124 TISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPD 183
            ++ R TG+    + N Q+  DL ++A+    +    LP M  FD F  +H ++ +    
Sbjct: 126 VMACRSTGFCLLSSHNVQQCHDLAIVAHLATLE--ASLPFMHFFDGFRTSHEIQKIHQLT 183

Query: 184 QEVVDEFLGEYEPKHAY---LDPKRPITQGTLAFPAHYMEARYLVWEAMENAR--KVIDE 238
            + +   +       A+   L+P  P  +GT   P   + +   +    +  +  +++ +
Sbjct: 184 YDQIKSLVDMKYVDRAHKRGLNPIHPSQRGTSQGPDVILPSLLKIKSNADYLKVPEIVQK 243

Query: 239 AFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVD---KKREEGYKVGAAKM 295
              +  +  GR Y+  E Y   DAE + V MG+    L++ VD   K+ EE  KVG   +
Sbjct: 244 YMDKVGELTGRHYKIFEYYGAADAERVVVVMGAAVPVLEECVDYLMKELEE--KVGVLSV 301

Query: 296 TVYRPFPVEE-IRELAKKTKVLAFIEKDISMGLYG-AVFTDASAALINESEKPLMLDFIA 353
            +YRP+  +  + +L      ++ +++    GL+G  ++ D +  L++  +    +    
Sbjct: 302 HLYRPWSAKHFLEQLPNTVTKISVLDRTKEAGLFGEPLYLDVATTLLDAGKHIKCVGGRY 361

Query: 354 GLGGRDVTFNQLDEALSIAKEALEKGKVEKP 384
           GLG ++ T        ++AK   +  K E+P
Sbjct: 362 GLGSKEFT-------PAMAKAVFDNLKNEEP 385


>pir||T43258 pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) pfoA precursor,
           hydrogenosomal - Trichomonas vaginalis
           >gi|622958|gb|AAA85494.1| (U16822) pyruvate:ferredoxin
           oxidoreductas proprotein [Trichomonas vaginalis]
           Length = 1157
           
 Score =  109 bits (270), Expect = 5e-23
 Identities = 96/335 (28%), Positives = 154/335 (45%), Gaps = 33/335 (9%)

Query: 28  FPITPSTLVPEKISEFVANGELDAEFIKV-----ESEHSAISALVGASAAGVRTFTATAS 82
           +PITP+T + E +  ++A G  +    KV     +SE  A +A+ GA+A G    T TAS
Sbjct: 31  YPITPATTMGELVDAWIAQGRKNIWGNKVHMAMMQSEGGAAAAVHGATAVGALCATFTAS 90

Query: 83  QGLALMHEVLFIAAGMRLPIVMAIGNRAL-SAPINIWNDWQDTISQRDTGWIQFYAENNQ 141
           QG  LM   ++   G   P V  I  R + ++ ++I+ND  D  + R TG    ++   Q
Sbjct: 91  QGALLMIPDMYKIIGEMCPAVFHISARCIATSALSIYNDHGDIYACRATGMPILFSNGVQ 150

Query: 142 EALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEVV-----DEFLGEYEP 196
           EA DL  +A+         LP +  FD F  +H +   E  D E +      + L  +  
Sbjct: 151 EAHDLAAVAHLTT--IHTGLPFIHTFDGFRTSHEINTYEELDNETLWPLIDQKALAAFRA 208

Query: 197 KHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEK-------KFGR 249
           +   L+P+ P  +GT+  P +       VW+  E  RK       E EK       K GR
Sbjct: 209 RS--LNPEHPSERGTICGPEY-------VWQMHEKLRKPFQALPTEVEKMMKALGDKTGR 259

Query: 250 KYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVEEIR-E 308
            Y+  +     D E + + MGS    +++++ +  E  +K G  K+ ++RPF VE     
Sbjct: 260 YYKPYQYAGPRDPENVIIMMGSGCDPVEEYITEHPE--FKTGLIKVHLFRPFSVEMFNAA 317

Query: 309 LAKKTKVLAFIEKDIS-MGLYGAVFTDASAALINE 342
           +    K +  ++K +   G    +F D +AALI E
Sbjct: 318 IPASVKKICVLDKVVDPTGPREPLFEDVAAALIGE 352


>pir||C75168 2-ketoglutarate ferredoxin oxidoreductase, chain alpha  (kora-1)
           PAB2359 - Pyrococcus abyssi (strain Orsay)
           >gi|5457936|emb|CAB49426.1| (AJ248284) 2-ketoglutarate
           ferredoxin oxidoreductase, subunit alpha (korA-1)
           [Pyrococcus abyssi]
           Length = 408
           
 Score =  108 bits (266), Expect = 2e-22
 Identities = 102/337 (30%), Positives = 155/337 (45%), Gaps = 26/337 (7%)

Query: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAL 66
           M  +EA A+ A  A  +  A +PITPS+ + E ++  +   ++   ++++E E ++I+A+
Sbjct: 37  MMGDEAVAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIASIAAM 94

Query: 67  VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTIS 126
           VGAS  G++  TAT+  G +LM E L  A     P+V+    R+  +        Q    
Sbjct: 95  VGASWTGLKVMTATSGPGFSLMQENLGYAVMTETPLVLVDVQRSGPSTGQATKGAQGDFF 154

Query: 127 QRDTGW------IQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180
           Q   G       +     + ++A    + A+ VAE  R+  P +V FD  IL HT E + 
Sbjct: 155 QARWGTHGDHPIVAISPVSVEDAFWETIRAFNVAE--RLRTPVVVLFDG-ILGHTREQIR 211

Query: 181 IPDQ---EVVDEFLGEYEPKHAYLDPKRPITQGTLAFP--AHYMEARYLVWEAMENARKV 235
           IPD    E+V   L + E + A L    P   G    P   H            EN  + 
Sbjct: 212 IPDPDEVEIVYRKLPQNE-EEARLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRD 270

Query: 236 I--DEAFAEFEKKFGRK-------YQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREE 286
           +   E   +  ++  RK       Y+K EEY TDDAEI+ V+ G  A      V K R+E
Sbjct: 271 VYTQEVHDKLVRRIHRKIEQNREVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKARKE 330

Query: 287 GYKVGAAKMTVYRPFPVEEIRELAKKTKVLAFIEKDI 323
           G KVG        PFP E +REL KK + +   E ++
Sbjct: 331 GIKVGLFVPKTVHPFPGERMRELGKKVRAILVPEMNL 367


>pir||B71047 probable ferredoxin oxidoreductase alpha subunit - Pyrococcus
           horikoshii >gi|3258095|dbj|BAA30778.1| (AP000006) 408aa
           long hypothetical ferredoxin oxidoreductase alpha
           subunit [Pyrococcus horikoshii]
           Length = 408
           
 Score =  105 bits (259), Expect = 1e-21
 Identities = 99/336 (29%), Positives = 148/336 (43%), Gaps = 24/336 (7%)

Query: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAL 66
           M  +EA A+ A  A  +  A +PITPS+ + E ++  +   ++   ++++E E  +I+A+
Sbjct: 37  MMGDEAIAYGAIFAGCRFYAGYPITPSSEIAETMARELP--KVGGYYLQMEDEIGSIAAM 94

Query: 67  VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTIS 126
           +GAS  G++  TAT+  G +LM E +  A     PIV+    R+  +        Q    
Sbjct: 95  IGASWTGLKAMTATSGPGFSLMQENIGYAVMTETPIVVVNVQRSGPSTGQATKGAQGDFF 154

Query: 127 QR------DTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180
           Q       D   I     + ++A    + A+ +AE  R   P +V FD  IL HT E + 
Sbjct: 155 QARWGTHGDHPMIAVSPISVEDAFWETIRAFNIAEKLRT--PVIVLFDG-ILGHTREQIR 211

Query: 181 IPDQEVVDEFL-----GEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKV 235
           IPD + V+         E E K  + DP          F   Y              R V
Sbjct: 212 IPDPDEVEITYRKLPGSEEEAKLPFGDPHGDGVPPMPLFGHGYFTHVTGSTHKENGLRDV 271

Query: 236 -IDEAFAEFEKKFGRK-------YQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEG 287
              E   +  ++  RK       Y+K EEY TDDAEI+ V+ G  A      V K REEG
Sbjct: 272 YTQEVHDKLVRRIHRKIEQNRDVYEKYEEYYTDDAEILVVSWGVSARPSLGAVLKAREEG 331

Query: 288 YKVGAAKMTVYRPFPVEEIRELAKKTKVLAFIEKDI 323
            K G        PFP E +REL KK + +   E ++
Sbjct: 332 IKAGLFVPKTVHPFPGERMRELGKKVRAILVPEMNL 367


>pir||T18528 probable pyruvate (flavodoxin) dehydrogenase (EC 1.2.99.-) -
           Giardia intestinalis >gi|960283|gb|AAA74894.1| (L27221)
           pyruvate:ferredoxin oxidoreductase [Giardia
           intestinalis]
           Length = 1253
           
 Score =  103 bits (255), Expect = 3e-21
 Identities = 87/330 (26%), Positives = 157/330 (47%), Gaps = 18/330 (5%)

Query: 26  AAFPITPSTLVPEKISEFVANGELD--AEFIKVE---SEHSAISALVGASAAGVRTFTAT 80
           A FPITPS+++ E I ++ A G+ +     + V    SE  AI    GA+ AG  T T +
Sbjct: 31  AIFPITPSSVMAEMIEQYAAQGKKNIFGNVVTVRQAWSELGAIGTCHGAATAGALTATFS 90

Query: 81  ASQGLALMHEVLFIAAGMRLPIVMAIGNRALS-APINIWNDWQDTISQRDTGWIQFYAEN 139
           +SQG+ LM   L+  AG R+P V+ +  R +  A  ++  D  D  +   T      + N
Sbjct: 91  SSQGVLLMISNLYHMAGERIPFVLHVATRTVGMAATSLATDHTDVYAIEGTNMCALSSCN 150

Query: 140 NQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEI-PDQEVVDEFLGE----- 193
            QE  D+ L+A+  A + +        F+ + ++H  E +++  D   + +FL E     
Sbjct: 151 VQECYDMSLVAHTTATNVQAAFCHF--FEGYRVSHQFETIQVFKDDADIKDFLSEDQLAK 208

Query: 194 YEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFEKKFGRKYQK 253
           +  ++A +D  RPI          +M+         ++    I+EAF    +K GR+Y  
Sbjct: 209 WRSENA-MDTDRPIASNIGLGGEIHMQIVESQGAVFDSIPYRIEEAFDLLHRKTGRRYHC 267

Query: 254 IEEYRTDDAEIIFVTMGSLAGTLKDWVDK-KREEGYKVGAAKMTVYRPFPVEEI-RELAK 311
            E +     +++ V MG+ + T ++ VD     E  +VG  ++ ++RPF +E     + K
Sbjct: 268 FEYFGHPTPDVVVVVMGATSLTFENVVDALVNRENRRVGFVRVRLFRPFSIELFSNAIPK 327

Query: 312 KTKVLAFIEKDIS-MGLYGAVFTDASAALI 340
             KV+  +++    +   G ++ +  AAL+
Sbjct: 328 SAKVVVALDRAPELLNAGGTLYRETLAALM 357


>pir||A69194 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain -
           Methanobacterium thermoautotrophicum (strain Delta H)
           >gi|2621790|gb|AAB85209.1| (AE000849) 2-oxoisovalerate
           oxidoreductase, beta subunit  [Methanobacterium
           thermoautotrophicum]
           Length = 348
           
 Score = 97.9 bits (240), Expect = 2e-19
 Identities = 87/311 (27%), Positives = 142/311 (44%), Gaps = 27/311 (8%)

Query: 6   VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65
           ++K N A    A  A       +PITP++ +  + S +     +  +F++ ESE +AI+ 
Sbjct: 1   MVKGNTAVIIGAMYAGCDCYFGYPITPASEILHEASRYFPM--VGRKFVQAESEEAAINM 58

Query: 66  LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINI---WNDWQ 122
           + GA+AAG R  TA++  G++L  E +   AG  LP V+    RA     NI     D+ 
Sbjct: 59  VYGAAAAGHRVMTASSGPGISLKQEGISFLAGAELPAVIVDVMRAGPGLGNIGPEQGDYN 118

Query: 123 DTISQRDTGWIQ---FYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPV 179
             +     G  +       + QE  DL + A+++A+  R   P +V  DA +L    EP+
Sbjct: 119 QIVKGGGHGNYRNMVLAPSSVQEMCDLTMEAFELADKYR--NPVVVLTDA-VLGQMAEPL 175

Query: 180 EIPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEA 239
             P++ V      E+ P  ++         G      + + + +L ++ +E     + E 
Sbjct: 176 RFPEEAV------EHRPDTSW------AVCGNRETMKNLVTSIFLDFDELEEFNFYLQEK 223

Query: 240 FAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYR 299
           +A  E+   R     EEY  DDAEI+ V  G  +   +  V+  R EG  VG  +     
Sbjct: 224 YARIEENEVR----YEEYLVDDAEIVMVAYGISSRVARSAVETARAEGINVGLLRPITLF 279

Query: 300 PFPVEEIRELA 310
           PFP + IRELA
Sbjct: 280 PFPSDRIRELA 290


>sp|O26800|VORB_METTH KETOISOVALERATE OXIDOREDUCTASE SUBUNIT VORB (VOR) (2-OXOISOVALERATE
           OXIDOREDUCTASE BETA CHAIN) (2-OXOISOVALERATE-FERREDOXIN
           OXIDOREDUCTASE BETA SUBUNIT)
           Length = 352
           
 Score = 97.9 bits (240), Expect = 2e-19
 Identities = 87/311 (27%), Positives = 142/311 (44%), Gaps = 27/311 (8%)

Query: 6   VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65
           ++K N A    A  A       +PITP++ +  + S +     +  +F++ ESE +AI+ 
Sbjct: 5   MVKGNTAVIIGAMYAGCDCYFGYPITPASEILHEASRYFPM--VGRKFVQAESEEAAINM 62

Query: 66  LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINI---WNDWQ 122
           + GA+AAG R  TA++  G++L  E +   AG  LP V+    RA     NI     D+ 
Sbjct: 63  VYGAAAAGHRVMTASSGPGISLKQEGISFLAGAELPAVIVDVMRAGPGLGNIGPEQGDYN 122

Query: 123 DTISQRDTGWIQ---FYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPV 179
             +     G  +       + QE  DL + A+++A+  R   P +V  DA +L    EP+
Sbjct: 123 QIVKGGGHGNYRNMVLAPSSVQEMCDLTMEAFELADKYR--NPVVVLTDA-VLGQMAEPL 179

Query: 180 EIPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEA 239
             P++ V      E+ P  ++         G      + + + +L ++ +E     + E 
Sbjct: 180 RFPEEAV------EHRPDTSW------AVCGNRETMKNLVTSIFLDFDELEEFNFYLQEK 227

Query: 240 FAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYR 299
           +A  E+   R     EEY  DDAEI+ V  G  +   +  V+  R EG  VG  +     
Sbjct: 228 YARIEENEVR----YEEYLVDDAEIVMVAYGISSRVARSAVETARAEGINVGLLRPITLF 283

Query: 300 PFPVEEIRELA 310
           PFP + IRELA
Sbjct: 284 PFPSDRIRELA 294


>pir||H69004 2-oxoglutarate--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain
           - Methanobacterium thermoautotrophicum (strain Delta H)
           >gi|2622136|gb|AAB85529.1| (AE000875) 2-oxoglutarate
           oxidoreductase, alpha subunit  [Methanobacterium
           thermoautotrophicum]
           Length = 378
           
 Score = 94.4 bits (231), Expect = 2e-18
 Identities = 89/339 (26%), Positives = 148/339 (43%), Gaps = 23/339 (6%)

Query: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAL 66
           ++ N+A A  A  A  +  A +PITPST + E+++  +        F+++E E  A+ A+
Sbjct: 9   IQGNDACARGAIKAGCRFFAGYPITPSTEIAEEMALLLPRE--GGVFVQMEDEIGALGAV 66

Query: 67  VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTIS 126
           +GA  +GVR  TAT+  G +LM E +  AA    P+V+    R   +        Q  + 
Sbjct: 67  IGAVWSGVRGMTATSGPGFSLMQEHVGYAAMTETPLVIVNVQRGSPSTGQPTMASQSDMM 126

Query: 127 QRDTGW------IQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180
           Q   G       I     + QE  D  + A+ +AE+ RV  P MV  D  I+ H  E + 
Sbjct: 127 QARWGSHGDYEIIALSPSSVQECFDFTVRAFNLAEEYRV--PVMVMGDE-IVGHMREKIT 183

Query: 181 IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAF 240
           IPD+  + +  G   P   +L    P   G    PA     R  V     +     D + 
Sbjct: 184 IPDRVKIRKRRGPSVPPEEFLPFSAP-EDGVPEMPAFGDGYRIPVTGLTHDEGGYPDASN 242

Query: 241 AEFEKKFGRKY-----------QKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYK 289
            E   +  ++              ++E  T+DA I  ++ G+ + ++   V   RE+G +
Sbjct: 243 PEGHHRLVKRLCDKILRHRDRISDVQEELTEDAYITVISYGAPSRSVATAVKMAREDGVR 302

Query: 290 VGAAKMTVYRPFPVEEIRELAKKTKVLAFIEKDISMGLY 328
            G  K+    PFP  E+R  A+++  L  +E ++    Y
Sbjct: 303 AGYLKINTPWPFPETEVRAAAERSGKLLVVEMNLGQMFY 341


>sp|O27112|KORA_METTH 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KETOGLUTARATE
           OXIDOREDUCTASE ALPHA CHAIN) (KOR)
           (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT)
           Length = 376
           
 Score = 94.4 bits (231), Expect = 2e-18
 Identities = 89/339 (26%), Positives = 148/339 (43%), Gaps = 23/339 (6%)

Query: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAL 66
           ++ N+A A  A  A  +  A +PITPST + E+++  +        F+++E E  A+ A+
Sbjct: 7   IQGNDACARGAIKAGCRFFAGYPITPSTEIAEEMALLLPRE--GGVFVQMEDEIGALGAV 64

Query: 67  VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTIS 126
           +GA  +GVR  TAT+  G +LM E +  AA    P+V+    R   +        Q  + 
Sbjct: 65  IGAVWSGVRGMTATSGPGFSLMQEHVGYAAMTETPLVIVNVQRGSPSTGQPTMASQSDMM 124

Query: 127 QRDTGW------IQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVE 180
           Q   G       I     + QE  D  + A+ +AE+ RV  P MV  D  I+ H  E + 
Sbjct: 125 QARWGSHGDYEIIALSPSSVQECFDFTVRAFNLAEEYRV--PVMVMGDE-IVGHMREKIT 181

Query: 181 IPDQEVVDEFLGEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAF 240
           IPD+  + +  G   P   +L    P   G    PA     R  V     +     D + 
Sbjct: 182 IPDRVKIRKRRGPSVPPEEFLPFSAP-EDGVPEMPAFGDGYRIPVTGLTHDEGGYPDASN 240

Query: 241 AEFEKKFGRKY-----------QKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYK 289
            E   +  ++              ++E  T+DA I  ++ G+ + ++   V   RE+G +
Sbjct: 241 PEGHHRLVKRLCDKILRHRDRISDVQEELTEDAYITVISYGAPSRSVATAVKMAREDGVR 300

Query: 290 VGAAKMTVYRPFPVEEIRELAKKTKVLAFIEKDISMGLY 328
            G  K+    PFP  E+R  A+++  L  +E ++    Y
Sbjct: 301 AGYLKINTPWPFPETEVRAAAERSGKLLVVEMNLGQMFY 339


>gb|AAD55757.1|AF146519_1 (AF146519) putative pyruvate:ferredoxin oxidoreductase 2 [Giardia
           intestinalis]
           Length = 512
           
 Score = 90.5 bits (221), Expect = 3e-17
 Identities = 69/244 (28%), Positives = 118/244 (48%), Gaps = 8/244 (3%)

Query: 70  SAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWNDWQDTISQR 128
           S  G+   T TASQGL LM   ++  AG  LP V  +  R ++   +++  D  D ++ R
Sbjct: 15  SDTGLLASTYTASQGLLLMIPNMYKMAGEHLPAVFHVAARTIATHSLSVHGDHADIMAVR 74

Query: 129 DTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEPVEIPDQEVVD 188
            TG     +E+ QEA+D+ + A+  A       P +  FD F  +HT++ VE+ D E + 
Sbjct: 75  QTGCTIMVSEDIQEAMDMAIAAHLTAIYSSY--PVVHAFDGFRTSHTIKKVELIDYEHLR 132

Query: 189 EFLGEYEPKHAY----LDPKRPITQGTLAFPAHYMEARYLVWEAMENARKVIDEAFAEFE 244
             +  Y+   A+    L P+ P  +G+   P  +M+A     +        ++ AF +  
Sbjct: 133 PHV-PYDEIEAFRQKSLSPQHPEMRGSCQGPPIWMQAGEADNKHYAEIPGHVERAFEKVR 191

Query: 245 KKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWVDKKREEGYKVGAAKMTVYRPFPVE 304
           +  GR Y+    +   DA  + + MGS   T+ + V+   E G KVG   + ++RPF  +
Sbjct: 192 EITGRSYKFFNYFGAPDATAVVIIMGSGYLTVHEVVEYLVERGDKVGVVCVHLFRPFCGD 251

Query: 305 EIRE 308
           ++ E
Sbjct: 252 KLLE 255


>pir||F75168 2-ketoglutarate ferredoxin oxidoreductase, chain alpha  (kora-2)
           PAB0346 - Pyrococcus abyssi (strain Orsay)
           >gi|5457939|emb|CAB49429.1| (AJ248284) 2-ketoglutarate
           ferredoxin oxidoreductase, subunit alpha (korA-2)
           [Pyrococcus abyssi]
           Length = 385
           
 Score = 89.3 bits (218), Expect = 7e-17
 Identities = 94/331 (28%), Positives = 148/331 (44%), Gaps = 32/331 (9%)

Query: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAL 66
           ++ +EA A AA LA  +  A +PITP++ + E ++ ++    +D   I++E E ++I+A+
Sbjct: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL--VDGVVIQMEDEIASIAAI 70

Query: 67  VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVM--------AIGNRALSAPINIW 118
           +GAS AG +  TAT+  G +LM E +  A     PIV+        + G   L +  +I 
Sbjct: 71  IGASWAGAKAMTATSGPGFSLMQENIGYAVMTETPIVVVDVQRGGPSTGQPTLPSQGDIM 130

Query: 119 NDWQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEP 178
                T    D   I       QEA D  + A+ +AE  R   P ++  DA +  H  E 
Sbjct: 131 QSIWGT--HGDHSLIVLSPSTVQEAFDFTIRAFNLAEKYRT--PVILLSDAEV-GHMRER 185

Query: 179 VEIPDQ---EVVDEFL--GEYEPKHAYLDPKRPITQGTLAFPAHYMEARYLVWEAMEN-- 231
           V IP+    E+V+  L   E E K  + DP          F   Y    Y+     +   
Sbjct: 186 VYIPEPDEIEIVNRKLPQNEEEAKLPFGDPHGDFVPPMPIFGRGY--RTYVTGLTHDERG 243

Query: 232 -----ARKVIDEAFAEFEKKFGRKYQKIEEYRT---DDAEIIFVTMGSLAGTLKDWVDKK 283
                 R+V +       +K  R  + I +Y     DDAE+  VT G +A +    + + 
Sbjct: 244 RPRTVEREVHERVIRRIVEKIERNKKDIFDYEARELDDAEVAIVTTGIVARSALRAIKEL 303

Query: 284 REEGYKVGAAKMTVYRPFPVEEIRELAKKTK 314
           RE G K G  K+    PF  E I ++A K +
Sbjct: 304 RELGIKAGLLKINTIWPFDFELIEKIAGKVE 334


>pir||F71046 probable ferredoxin oxidoreductase alpha subunit - Pyrococcus
           horikoshii >gi|3258091|dbj|BAA30774.1| (AP000006) 385aa
           long hypothetical ferredoxin oxidoreductase alpha
           subunit [Pyrococcus horikoshii]
           Length = 385
           
 Score = 87.4 bits (213), Expect = 3e-16
 Identities = 95/329 (28%), Positives = 145/329 (43%), Gaps = 28/329 (8%)

Query: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAL 66
           ++ +EA A AA LA  +  A +PITP++ + E ++ ++    +D   I++E E  +I+A+
Sbjct: 13  IQGDEAIARAAILAGCRFYAGYPITPASEIFEAMALYMPL--IDGVVIQMEDEIGSIAAV 70

Query: 67  VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVM--------AIGNRALSAPINIW 118
           +GAS AGV+  TAT+  G +LM E +  A     PIV+        + G   L +  +I 
Sbjct: 71  IGASWAGVKAMTATSGPGFSLMQENIGYAVMTETPIVVVNVQRGGPSTGQPTLPSQGDIM 130

Query: 119 NDWQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVEP 178
                T    D   I       QEA D  + A+ +AE  R   P ++  DA +  H  E 
Sbjct: 131 QSIWGT--HGDHTLIVLSPSTVQEAFDFTIRAFNLAEKYRT--PVILLSDAEV-GHMRER 185

Query: 179 VEIPDQ---EVVDEFL--GEYEPKHAYLDPKRPITQGTLAFPAHYME-ARYLVWEAMENA 232
           V IP+    E+V+  L   E E K  + DP          F   Y      L  +     
Sbjct: 186 VYIPEPDEIEIVNRKLPGSEEEAKLPFGDPHGDGVPPMPIFGKGYRTYVTGLTHDEKGRP 245

Query: 233 RKVIDEAFAEFEKKFGRKYQK-------IEEYRTDDAEIIFVTMGSLAGTLKDWVDKKRE 285
           R V  E      ++   K +K        E    DDAEI  VT G +A +    + + R 
Sbjct: 246 RTVEREVHERLIRRIFEKIEKNKKDIFDYEARELDDAEIAIVTTGIVARSALRAIKELRN 305

Query: 286 EGYKVGAAKMTVYRPFPVEEIRELAKKTK 314
            G K G  K+    PF  E I ++A+K +
Sbjct: 306 LGIKAGLLKINTIWPFDFELIEKVAEKVE 334


>sp|Q57724|KORA_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA (2-KETOGLUTARATE
           OXIDOREDUCTASE ALPHA CHAIN) (KOR)
           (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE ALPHA SUBUNIT)
           >gi|2127893|pir||E64334 2-oxoacid--ferredoxin
           oxidoreductase (EC 1.2.7.-) alpha chain - Methanococcus
           jannaschii >gi|1592279|gb|AAB98264.1| (U67483)
           2-ketoglutarate ferredoxin oxidoreductase, subunit alpha
           (korA) [Methanococcus jannaschii]
           Length = 366
           
 Score = 85.0 bits (207), Expect = 1e-15
 Identities = 95/366 (25%), Positives = 168/366 (44%), Gaps = 37/366 (10%)

Query: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISAL 66
           M+ N+A A  A  A  +  A +PITPST + E ++  +   ++   +I++E E  +I+A+
Sbjct: 6   MQGNQACAKGAIKAGCRFFAGYPITPSTEIAEAMARELP--KVGGYYIQMEDEIGSIAAV 63

Query: 67  VGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVM--------AIGNRALSAPINIW 118
           +GAS  G++  TAT+  G +LM E +  A     P V+        + G   +++  ++ 
Sbjct: 64  IGASWGGLKAMTATSGPGFSLMQENIGFAYMTETPCVVVDIQRGGPSTGQPTMASQGDMM 123

Query: 119 N-DWQDTISQRDTGWIQFYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTHTVE 177
              W    S  D   I     + QE  D  ++A+  AE  R+  P  V  D  I+ H  E
Sbjct: 124 QCRWG---SHGDYEVIALAPSSVQEMYDFTIMAFNYAEKYRI--PVFVMADE-IVGHMRE 177

Query: 178 PVEIPDQ-EVVDEFLGEYEP-KHAY----LDPKRPITQGTLAFPAHYMEARYLVWEAMEN 231
            V + D  E+++    E +P K  Y    L P+ P+      +  H     +      + 
Sbjct: 178 KVILHDNIEIINRKKPEEKPCKKPYPFDKLIPEMPVFGE--GYNVHITGLTHDERGYPDV 235

Query: 232 ARKVIDEAFAEFEKKFGRKYQKIEEYRTD--DAEIIFVTMGSLAGTLKDWVDKKREEGYK 289
           + +  D+       K  +   +I ++  +  DAEI+FV  GS + T+K  V   RE+G  
Sbjct: 236 SPETHDKLVRRIVNKIRKNKDEIIKWEGENLDAEIVFVCYGSPSRTVKHAVRNLREKGLD 295

Query: 290 VGAAKMTVYRPFPVEEIRELAKKTKVLAFIEKDISMG-LYGAVFTDASAALINESEKPLM 348
           VG  ++    PFP     +L KK K    +  ++++G +Y  V       +  ++E+ ++
Sbjct: 296 VGYIRLITVYPFP----DDLLKKLKAKKVVVPEMNLGQIYYEV-----ERVCKKAEEVIL 346

Query: 349 LDFIAG 354
           +D I G
Sbjct: 347 VDKIGG 352


>emb|CAA34396.1| (X16345) nifJ [Klebsiella pneumoniae]
           Length = 167
           
 Score = 80.4 bits (195), Expect = 3e-14
 Identities = 56/150 (37%), Positives = 81/150 (53%), Gaps = 8/150 (5%)

Query: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELD-----AEFIKVESEHS 61
           M  N AAAW +  A  +V A +PITPST + E + E+ A G+ +        ++++SE  
Sbjct: 8   MDGNAAAAWIS-YAFTEVAAIYPITPSTPMAENVDEWAAQGKKNLFGQPVRLMEMQSEAG 66

Query: 62  AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWND 120
           A  A+ GA  AG  T T TASQGL LM   ++  AG  LP V  +  RAL+   +NI+ D
Sbjct: 67  AAGAVHGALQAGALTTTYTASQGLLLMIPNMYKIAGELLPGVFHVSARALATNSLNIFGD 126

Query: 121 WQDTISQRDTGWIQFYAENNQEALDLILLA 150
             D ++ R +G       N Q+ +DL  +A
Sbjct: 127 -HDVMAVRQSGCAMLAENNVQQVMDLSTIA 155


>pir||E64593 2-oxoacid--ferredoxin oxidoreductase (EC 1.2.7.-) alpha chain -
           Helicobacter pylori (strain 26695)
           >gi|2313707|gb|AAD07654.1| (AE000572) ferredoxin
           oxidoreductase, alpha subunit [Helicobacter pylori
           26695]
           Length = 375
           
 Score = 72.2 bits (174), Expect = 1e-11
 Identities = 85/341 (24%), Positives = 146/341 (41%), Gaps = 37/341 (10%)

Query: 6   VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65
           +   NE  A AA     +    +PITPS+ +   +S  VA  +    FI++E E S IS 
Sbjct: 5   ISDGNELVAKAAIEVGCRFFGGYPITPSSDIMHAMS--VALPKCGGHFIQMEDEISGISV 62

Query: 66  LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125
            +GAS +G ++ TA++  G++L  E +  +    +P+V+A   R  S P          +
Sbjct: 63  SLGASMSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMR--SGPS---TGMPTRV 117

Query: 126 SQRDTGWIQ-----------FYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTH 174
           +Q D  +++               N +EA    + A+ +A  E ++ P  +  D  +  H
Sbjct: 118 AQGDVNFLRHPIHGDFKAVALAPANLEEAYTETVRAFNLA--EMLMTPVFLLMDETV-GH 174

Query: 175 TVEPVEIPDQEVVD-------EFLG---EYEPKHAYLDPKRPITQGTLAFPAHYMEARY- 223
               V+IPD E V        EFLG   +Y+P     D    +      +  H     + 
Sbjct: 175 MYGKVQIPDLEEVQKMTINRKEFLGDKKDYKPYGVAQDEPAVLNPFFKGYRYHVSGLHHG 234

Query: 224 ---LVWEAMENARKVIDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWV 280
                 E  +    +ID  F + E K      + EE   + AEI+ +  GS++  +K+ +
Sbjct: 235 PIGFPTEDAKIGGDLIDRLFNKIESK-QDIINENEEMDLEGAEIVVIAYGSVSLAVKEAL 293

Query: 281 -DKKREEGYKVGAAKMTVYRPFPVEEIRELAKKTKVLAFIE 320
            D  +E   KVG  +     P P + ++E+  K + +  IE
Sbjct: 294 KDYHKESKQKVGFFRPKTLWPSPAKRLKEIGDKYEKILVIE 334


>gb|AAC38211.1| (AF021094) OorA subunit of 2-oxoglutarate:acceptor oxidoreductase
           [Helicobacter pylori]
           Length = 371
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 84/338 (24%), Positives = 143/338 (41%), Gaps = 31/338 (9%)

Query: 6   VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65
           +   NE  A AA     +    +PITPS+ +   +S  VA       FI++E E S IS 
Sbjct: 5   ISDGNELVAKAAIEVGCRFFGGYPITPSSDIMHAMS--VALPNCGGHFIQMEDEISGISV 62

Query: 66  LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125
            +GAS +G ++ TA++  G++L  E +  +    +P+V+A   R  S P          +
Sbjct: 63  SLGASMSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMR--SGPS---TGMPTRV 117

Query: 126 SQRDTGWIQFYAENNQEALDLILLAYKVAEDERVL---LPAMVGFDAFILT-----HTVE 177
            Q D  +++     + +A+ L   + + A  E      L  M+    F+L      H   
Sbjct: 118 DQGDVNFLRHPIHGDFKAVALAPASLEEAYTETARAFNLAEMLMTPVFLLMDETVGHMYG 177

Query: 178 PVEIPDQEVVD-------EFLG---EYEPKHAYLDPKRPITQGTLAFPAHYMEARY---- 223
            V+IPD E V        EF+G   +Y+P     D    +      +  H     +    
Sbjct: 178 KVQIPDLEEVQKTTINRKEFVGDKKDYKPYGVAQDEPAVLNPFFKGYRYHVSGLHHGPIG 237

Query: 224 LVWEAMENARKVIDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWV-DK 282
              E  +    +ID  F + E K      + EE   + AEI+ +  GS++  +K+ + D 
Sbjct: 238 FPTEDAKIGGDLIDRLFNKIESK-QDIINENEEMDLEGAEIVIIAYGSVSLAVKEALKDY 296

Query: 283 KREEGYKVGAAKMTVYRPFPVEEIRELAKKTKVLAFIE 320
            +E   KVG  +     P P + ++E+  K + +  IE
Sbjct: 297 HKESNQKVGFFRPKTLWPSPAKRLKEIGDKYEKILVIE 334


>emb|CAA25502.1| (X01007) URF [Klebsiella pneumoniae]
           Length = 127
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 48/120 (40%), Positives = 67/120 (55%), Gaps = 7/120 (5%)

Query: 7   MKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELD-----AEFIKVESEHS 61
           M  N AAAW +  A  +V A +PITPST + E + E+ A G+ +        ++++SE  
Sbjct: 8   MDGNAAAAWIS-YAFTEVAAIYPITPSTPMAENVDEWAAQGKKNLFGQPVRLMEMQSEAG 66

Query: 62  AISALVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSA-PINIWND 120
           A  A+ GA  AG  T T TASQGL LM   ++  AG  LP V  +  RAL+   +NI+ D
Sbjct: 67  AAGAVHGALQAGALTTTYTASQGLLLMIPNMYKIAGELLPGVFHVSARALATNSLNIFGD 126


>pir||G71919 chain of 2-oxoglutarate oxidoreductase - Helicobacter pylori
           (strain J99) >gi|4155084|gb|AAD06119.1| (AE001486)
           SUBUNIT OF 2-OXOGLUTARATE OXIDOREDUCTASE [Helicobacter
           pylori J99]
           Length = 375
           
 Score = 69.5 bits (167), Expect = 6e-11
 Identities = 83/341 (24%), Positives = 144/341 (41%), Gaps = 37/341 (10%)

Query: 6   VMKANEAAAWAAKLAKPKVIAAFPITPSTLVPEKISEFVANGELDAEFIKVESEHSAISA 65
           +   NE  A AA     +    +PITPS+ +   +S  VA  +    FI++E E S IS 
Sbjct: 5   ISDGNELVAKAAIEVGCRFFGGYPITPSSDIMHAMS--VALPKCGGHFIQMEDEISGISV 62

Query: 66  LVGASAAGVRTFTATASQGLALMHEVLFIAAGMRLPIVMAIGNRALSAPINIWNDWQDTI 125
            +GAS +G ++ TA++  G++L  E +  +    +P+V+A   R  S P          +
Sbjct: 63  SLGASMSGTKSMTASSGPGISLKVEQIGYSFMAEIPLVIADVMR--SGPS---TGMPTRV 117

Query: 126 SQRDTGWIQ-----------FYAENNQEALDLILLAYKVAEDERVLLPAMVGFDAFILTH 174
           +Q D  +++               N +EA    + A+ +A  E ++ P  +  D  +  H
Sbjct: 118 AQGDVNFLRHPIHGDFKAVALAPANLEEAYTETVRAFNLA--EMLMTPVFLLMDETV-GH 174

Query: 175 TVEPVEIPDQEVVD-------EFLG---EYEPKHAYLDPKRPITQGTLAFPAHYMEARY- 223
               V+IPD E V        EF G   +Y+P     D    +      +  H     + 
Sbjct: 175 MYGKVQIPDLEEVQKMTINRKEFAGDKKDYKPYGVAQDEPAVLNPFFKGYRYHVSGLHHG 234

Query: 224 ---LVWEAMENARKVIDEAFAEFEKKFGRKYQKIEEYRTDDAEIIFVTMGSLAGTLKDWV 280
                 E  +    +ID  F + E K      + EE   +  EI+ +  GS++  +K+ +
Sbjct: 235 PIGFPTEDAKIGGDLIDRLFHKIESK-QDIINENEEMDLEGTEIVIIAYGSVSLAVKEAL 293

Query: 281 -DKKREEGYKVGAAKMTVYRPFPVEEIRELAKKTKVLAFIE 320
            D  +E   KVG  +     P P + ++E+  K + +  IE
Sbjct: 294 KDYNKESKQKVGFFRPKTLWPSPAKRLKEIGDKYEKILVIE 334


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.319    0.135    0.387 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 138190127
Number of Sequences: 2977
Number of extensions: 5664194
Number of successful extensions: 16900
Number of sequences better than 1.0e-10: 69
Number of HSP's better than  0.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 41
Number of HSP's that attempted gapping in prelim test: 16697
Number of HSP's gapped (non-prelim): 75
length of query: 395
length of database: 189,106,746
effective HSP length: 58
effective length of query: 337
effective length of database: 154,394,500
effective search space: 52030946500
effective search space used: 52030946500
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 166 (69.1 bits)