BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1490 (thrS) DE:threonyl-tRNA synthetase (thrS)
         (625 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||C75044 threonyl-tRNA synthetase (thrs) PAB1490 - Pyrococcus...  1262  0.0
sp|O58430|SYT_PYRHO THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...  1186  0.0
gi|11498158 threonyl-tRNA synthetase (thrS) [Archaeoglobus fulgi...   775  0.0
sp|Q58597|SYT_METJA THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...   581  e-165
pir||D64449 threonine--tRNA ligase (EC 6.1.1.3) - Methanococcus ...   581  e-165
sp|O27504|SYT_METTH THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...   574  e-162
sp|P56881|SYT_THETH THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...   184  3e-45
sp|P18255|SYT1_BACSU THREONYL-TRNA SYNTHETASE 1 (THREONINE--TRNA...   182  8e-45
sp|P18256|SYT2_BACSU THREONYL-TRNA SYNTHETASE 2 (THREONINE--TRNA...   177  4e-43
emb|CAB02510.1| (Z80360) Threonyl tRNA Synthetase [Bacillus subt...   177  4e-43
sp|Q55806|SYT_SYNY3 THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...   176  6e-43
gb|AAG20043.1| (AE005084) threonyl-tRNA synthetase; ThrS [Haloba...   174  3e-42
pir||B75317 threonyl-tRNA synthetase - Deinococcus radiodurans (...   173  5e-42
dbj|BAB06860.1| (AP001517) threonyl-tRNA synthetase 1 [Bacillus ...   171  3e-41
gb|AAK42622.1| Threonyl-tRNA synthetase (thrS) [Sulfolobus solfa...   165  2e-39
sp|Q9WZJ9|SYT_THEMA THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...   163  6e-39
sp|O05947|SYT_RICPR THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...   162  8e-39
sp|O67583|SYT_AQUAE THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...   161  2e-38
pir||A82479 threonyl-tRNA synthetase VCA0287 [imported] - Vibrio...   160  5e-38
pir||H82878 threonyl-tRNA synthetase UU534 [imported] - Ureaplas...   157  4e-37
sp|O51662|SYT_BORBU THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...   155  1e-36
sp|Q9ZMV3|SYT_HELPJ THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...   153  4e-36
sp|P56071|SYT_HELPY THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...   150  3e-35
sp|O83809|SYT_TREPA THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...   150  6e-35
pir||T51624 threonine--tRNA ligase (EC 6.1.1.3) [imported] - Ara...   149  1e-34
pir||B81939 probable threonine--tRNA ligase (EC 6.1.1.3) NMA0929...   148  1e-34
pir||E81167 threonyl-tRNA synthetase NMB0720 [imported] - Neisse...   148  2e-34
gb|AAF53166.1| (AE003635) CG5353 gene product [alt 1] [Drosophil...   147  3e-34
sp|O07151|SYT_MYCLE THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...   147  3e-34
dbj|BAA15486.1| (D90813) Threonine--tRNA ligase (EC 6.1.1.3) [Es...   146  5e-34
pdb|1EVK|A Chain A, Crystal Structure Of A Truncated Form Of Thr...   146  5e-34
sp|P00955|SYT_ECOLI THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...   146  5e-34
emb|CAA23560.1| (V00291) threonyl-tRNA synthetase (thrS; EC 6.1....   146  5e-34
emb|CAB70933.1| (AL137778) threonine-tRNA synthetase [Streptomyc...   143  7e-33
sp|P52709|SYTC_CAEEL PROBABLE THREONYL-TRNA SYNTHETASE, CYTOPLAS...   142  1e-32
sp|O06200|SYT_MYCTU THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...   139  6e-32
sp|P57225|SYT_BUCAI THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...   139  6e-32
sp|O04630|SYTC_ARATH PROBABLE THREONYL-TRNA SYNTHETASE, CYTOPLAS...   139  1e-31
sp|Q9Z7A0|SYT_CHLPN THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...   138  2e-31
sp|O84585|SYT_CHLTR THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...   138  2e-31
pir||G71497 threonine--tRNA ligase (EC 6.1.1.3) - Chlamydia trac...   138  2e-31
sp|P47615|SYT_MYCGE THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...   137  3e-31
sp|P75225|SYT_MYCPN THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...   137  3e-31
pir||F83303 threonyl-tRNA synthetase PA2744 [imported] - Pseudom...   136  7e-31
pir||D82770 threonyl-tRNA synthetase XF0736 [imported] - Xylella...   135  2e-30
pir||A81656 threonyl-tRNA synthetase TC0870 [imported] - Chlamyd...   134  3e-30
sp|P43014|SYT_HAEIN THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...   133  5e-30
gi|4507367 threonyl-tRNA synthetase [Homo sapiens] >gi|135177|sp...   133  6e-30
sp|P87144|SYTC_SCHPO THREONYL-TRNA SYNTHETASE, CYTOPLASMIC (THRE...   129  9e-29
emb|CAC11475.1| (AL445064) threonine--tRNA ligase related protei...   129  1e-28
emb|CAC10316.1| (AL442629) SCH63.25, possible threonyl tRNA synt...   128  2e-28
pir||E81439 threonine--tRNA ligase (EC 6.1.1.3) Cj0206 [imported...   126  8e-28
gb|AAK40712.1| Threonyl-tRNA synthetase homolog (thrS-like) [Sul...   118  1e-25
sp|P46244|SYT_BUCAP THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...   116  7e-25
emb|CAA21975.1| (AL033497) mitochondrial threonyl tRNA synthetas...   116  7e-25
gb|AAF97275.1|AC034106_18 (AC034106) Strong similarity to threon...   116  9e-25
gi|6322654 mitochondrial threonine-tRNA synthetase; Mst1p [Sacch...   113  8e-24
gb|AAA34808.1| (M12087) thr-tRNA-synthetase [Saccharomyces cerev...   112  1e-23
emb|CAA26666.1| (X02906) threonyl-tRNA synthetase (aa 1-734) [Sa...   111  3e-23
gi|6322112 Threonyl-tRNA synthetase, cytoplasmic; Ths1p [Sacchar...   111  3e-23
dbj|BAB14117.1| (AK022590) unnamed protein product [Homo sapiens]     102  9e-21
sp|O13969|SYTM_SCHPO PROBABLE THREONYL-TRNA SYNTHETASE, MITOCHON...    99  2e-19
sp|Q9YFY3|SYT2_AERPE PROBABLE THREONYL-TRNA SYNTHETASE 2 (THREON...    85  2e-15
sp|P52833|SYT_PSESY THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI...    85  3e-15
gb|AAD34790.1|AF136400_4 (AF136400) threonyl-tRNA synthetase [Ps...    80  1e-13
gb|AAF78372.1|AC069551_5 (AC069551) T10O22.10 [Arabidopsis thali...    80  1e-13
gb|AAF97829.1|AC034107_12 (AC034107) Contains similarity to thre...    73  9e-12

>pir||C75044 threonyl-tRNA synthetase (thrs) PAB1490 - Pyrococcus abyssi
           (strain Orsay) >gi|5458761|emb|CAB50248.1| (AJ248287)
           threonyl-tRNA synthetase (thrS) [Pyrococcus abyssi]
           Length = 625
           
 Score = 1262 bits (3231), Expect = 0.0
 Identities = 625/625 (100%), Positives = 625/625 (100%)

Query: 1   MRVLLIHSDYIEYEVKDKALKNPEPISEDMKRGRMEEVLVAFISVEKVDEKNPEEVSLKA 60
           MRVLLIHSDYIEYEVKDKALKNPEPISEDMKRGRMEEVLVAFISVEKVDEKNPEEVSLKA
Sbjct: 1   MRVLLIHSDYIEYEVKDKALKNPEPISEDMKRGRMEEVLVAFISVEKVDEKNPEEVSLKA 60

Query: 61  IEEISKVAEQVKAENVFVYPFAHLSSELAKPSVAMDILNRVYQGLKERGFNVGKAPFGYY 120
           IEEISKVAEQVKAENVFVYPFAHLSSELAKPSVAMDILNRVYQGLKERGFNVGKAPFGYY
Sbjct: 61  IEEISKVAEQVKAENVFVYPFAHLSSELAKPSVAMDILNRVYQGLKERGFNVGKAPFGYY 120

Query: 121 KAFKISCKGHPLAELSRTIVPEEARVEEVPEALRKEEEELVSYWYILTPEGELIEVDKFD 180
           KAFKISCKGHPLAELSRTIVPEEARVEEVPEALRKEEEELVSYWYILTPEGELIEVDKFD
Sbjct: 121 KAFKISCKGHPLAELSRTIVPEEARVEEVPEALRKEEEELVSYWYILTPEGELIEVDKFD 180

Query: 181 FTGYENLRKFVNYEIAKNRIAEKEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSL 240
           FTGYENLRKFVNYEIAKNRIAEKEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSL
Sbjct: 181 FTGYENLRKFVNYEIAKNRIAEKEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSL 240

Query: 241 LEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIVLSGDKRYFLRFAACFG 300
           LEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIVLSGDKRYFLRFAACFG
Sbjct: 241 LEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIVLSGDKRYFLRFAACFG 300

Query: 301 QFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAK 360
           QFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAK
Sbjct: 301 QFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAK 360

Query: 361 EEFKKQFKLSMEVLEGVGLTPEDYEVAIRFTEDFWKEHKDFIVELVKLIGKPVLIEMWKQ 420
           EEFKKQFKLSMEVLEGVGLTPEDYEVAIRFTEDFWKEHKDFIVELVKLIGKPVLIEMWKQ
Sbjct: 361 EEFKKQFKLSMEVLEGVGLTPEDYEVAIRFTEDFWKEHKDFIVELVKLIGKPVLIEMWKQ 420

Query: 421 RFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGA 480
           RFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGA
Sbjct: 421 RFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGA 480

Query: 481 IERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRV 540
           IERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRV
Sbjct: 481 IERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRV 540

Query: 541 DVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYETRIEELIKEIK 600
           DVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYETRIEELIKEIK
Sbjct: 541 DVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYETRIEELIKEIK 600

Query: 601 EKTEGFPYKPRPLPLLLSKRPKFRG 625
           EKTEGFPYKPRPLPLLLSKRPKFRG
Sbjct: 601 EKTEGFPYKPRPLPLLLSKRPKFRG 625


>sp|O58430|SYT_PYRHO THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|7450857|pir||D71116 threonine--tRNA ligase (EC
           6.1.1.3) - Pyrococcus horikoshii
           >gi|3257107|dbj|BAA29790.1| (AP000003) 625aa long
           hypothetical threonyl-tRNA synthetase [Pyrococcus
           horikoshii]
           Length = 625
           
 Score = 1186 bits (3035), Expect = 0.0
 Identities = 575/625 (92%), Positives = 607/625 (97%)

Query: 1   MRVLLIHSDYIEYEVKDKALKNPEPISEDMKRGRMEEVLVAFISVEKVDEKNPEEVSLKA 60
           MR+LLIHSDYIEYEVKDKA+KNPEPISE+ K+GRM+EVLVAFISVEKVDE NPEEV  KA
Sbjct: 1   MRILLIHSDYIEYEVKDKAIKNPEPISEEEKKGRMDEVLVAFISVEKVDETNPEEVVSKA 60

Query: 61  IEEISKVAEQVKAENVFVYPFAHLSSELAKPSVAMDILNRVYQGLKERGFNVGKAPFGYY 120
           +EEI  VA QVKAENVFVYPFAHLSSELAKPSVA +IL +VY+GLKE+G+NVGKAPFGYY
Sbjct: 61  VEEIINVASQVKAENVFVYPFAHLSSELAKPSVAQEILRKVYEGLKEKGYNVGKAPFGYY 120

Query: 121 KAFKISCKGHPLAELSRTIVPEEARVEEVPEALRKEEEELVSYWYILTPEGELIEVDKFD 180
           KAFKISCKGHPLAELSRTI+PE A+ EEVPEAL+KEE ELVSYWYILTPEGELIEVDKFD
Sbjct: 121 KAFKISCKGHPLAELSRTIIPEGAKEEEVPEALKKEETELVSYWYILTPEGELIEVDKFD 180

Query: 181 FTGYENLRKFVNYEIAKNRIAEKEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSL 240
           FTGYENLRKF NYEI+K+RIAEKEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSL
Sbjct: 181 FTGYENLRKFANYEISKSRIAEKEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSL 240

Query: 241 LEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIVLSGDKRYFLRFAACFG 300
           LEQYVTEKVIEYGAMEVETP+MYDFEHPALEKYLNRFPARQYIVLSGDK+YFLRFAACFG
Sbjct: 241 LEQYVTEKVIEYGAMEVETPVMYDFEHPALEKYLNRFPARQYIVLSGDKKYFLRFAACFG 300

Query: 301 QFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAK 360
           QF+I KDA+ISYR+LPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKD+EQAK
Sbjct: 301 QFLISKDAVISYRHLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDLEQAK 360

Query: 361 EEFKKQFKLSMEVLEGVGLTPEDYEVAIRFTEDFWKEHKDFIVELVKLIGKPVLIEMWKQ 420
           +EFKKQFKLSMEVL+GVGLTPEDYEVAIRFTEDFWKE++DFIVELVK+IGKPVLIEMWKQ
Sbjct: 361 DEFKKQFKLSMEVLKGVGLTPEDYEVAIRFTEDFWKENRDFIVELVKIIGKPVLIEMWKQ 420

Query: 421 RFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGA 480
           RFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGI YYDENGEEKYPLILHCSPSGA
Sbjct: 421 RFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGIKYYDENGEEKYPLILHCSPSGA 480

Query: 481 IERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRV 540
           IERVMYAILEKQAKLM EGKKPM PLWLSPIQVRVIPVSEEYLDYALY+AGKLEGA+IRV
Sbjct: 481 IERVMYAILEKQAKLMQEGKKPMLPLWLSPIQVRVIPVSEEYLDYALYIAGKLEGARIRV 540

Query: 541 DVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYETRIEELIKEIK 600
           DVDDEDERLNKKIRRAEKEWIPYIVVVGA+EKE+GTITVRRREDGKQYETR+EELIKEIK
Sbjct: 541 DVDDEDERLNKKIRRAEKEWIPYIVVVGAKEKESGTITVRRREDGKQYETRLEELIKEIK 600

Query: 601 EKTEGFPYKPRPLPLLLSKRPKFRG 625
           EK EGFPYKPRPLPLLLSKRPKFRG
Sbjct: 601 EKVEGFPYKPRPLPLLLSKRPKFRG 625


>gi|11498158 threonyl-tRNA synthetase (thrS) [Archaeoglobus fulgidus]
           >gi|3334363|sp|O29703|SYT_ARCFU THREONYL-TRNA SYNTHETASE
           (THREONINE--TRNA LIGASE) (THRRS) >gi|7450858|pir||D69318
           threonyl-tRNA synthetase (thrS) homolog - Archaeoglobus
           fulgidus >gi|2650076|gb|AAB90685.1| (AE001066)
           threonyl-tRNA synthetase (thrS) [Archaeoglobus fulgidus]
           Length = 619
           
 Score =  775 bits (1980), Expect = 0.0
 Identities = 388/629 (61%), Positives = 487/629 (76%), Gaps = 15/629 (2%)

Query: 1   MRVLLIHSDYIEYEVKDKALKNPEPISEDMKRGRMEEVLVAFISVEKVDEKNPEEVSLKA 60
           M++LLIH+DY+EYEVK K  K  EP   D K  R+EEVLVAF SVEK D++N   V  KA
Sbjct: 1   MKLLLIHADYMEYEVKKKT-KLAEPF--DGKGERVEEVLVAFTSVEKGDDEN---VVRKA 54

Query: 61  IEEISKVAEQVKAENVFVYPFAHLSSELAKPSVAMDILNRVYQGLKERGFNVGKAPFGYY 120
            E I +VAE+V AE + +YP+AHLSS LA    A+ +L ++   L +  F V ++PFG+Y
Sbjct: 55  AEAIREVAEKVNAERIMIYPYAHLSSNLADAETAVKLLKQLEAELSD--FEVHRSPFGWY 112

Query: 121 KAFKISCKGHPLAELSRTIVPEEARVEEVPEALRKEEEELVSYWYILTPEGELIEVDKFD 180
           KAF+ISCKGHPL+ELSR I  E     EV +AL+ EEE++VSYWYILTPE EL+EV+KFD
Sbjct: 113 KAFRISCKGHPLSELSREIGGEAEA--EVTQALKDEEEKVVSYWYILTPEKELVEVEKFD 170

Query: 181 FTGYENLRKFVNYEIAKNRIAEKEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSL 240
           FTGYE LRKFVNYEIAK R  +  PPHV+ M   EL DYEP SD G++RYYPKGRL+K+L
Sbjct: 171 FTGYEKLRKFVNYEIAKRRAVDVTPPHVEYMRRLELADYEPASDSGHIRYYPKGRLVKTL 230

Query: 241 LEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIVLSGDKRYFLRFAACFG 300
           LEQ++T K I+YGAMEVETPIMYD  HP L +YL RFPARQYI+    + +FLRFAACFG
Sbjct: 231 LEQFITRKCIDYGAMEVETPIMYDRNHPTLRRYLERFPARQYIIKGDKREFFLRFAACFG 290

Query: 301 QFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAK 360
           QF++   + I+YRNLPL++YELTRYSFR+E+RGEL GLRRLRAFTMPDMHT+AKD+EQAK
Sbjct: 291 QFLMLSSSTITYRNLPLKIYELTRYSFRKEQRGELVGLRRLRAFTMPDMHTVAKDMEQAK 350

Query: 361 EEFKKQFKLSMEVLEGVGLTPEDYEVAIRFTEDFWKEHKDFIVELVKLIGKPVLIEMWKQ 420
           EEF  Q++LS+EVL  +GL PEDYEVA+R T+DF++E+++F+  LV ++ KP+LIEMW  
Sbjct: 351 EEFFNQYRLSVEVLREIGLEPEDYEVAVRITKDFYEENREFVHSLVDILKKPILIEMWDH 410

Query: 421 RFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGA 480
           RFFYF+LKFEFNFVD LDKA+ALSTVQIDVENAER+GIT+ D +G+EK+P ILHCS SGA
Sbjct: 411 RFFYFVLKFEFNFVDALDKASALSTVQIDVENAERYGITFVDSDGKEKHPYILHCSVSGA 470

Query: 481 IERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRV 540
           +ERVMYA+LEK   +++EG+ PM P+WLSP QVRVIPVSE ++D A+ +A  +    IRV
Sbjct: 471 VERVMYALLEKAKFMLDEGRLPMLPVWLSPTQVRVIPVSERFVDAAIKIADDIARNGIRV 530

Query: 541 DVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENG--TITVR---RREDGKQYETRIEEL 595
           DVDD +E L KKIR A+ EWIPYI VVG +E E+G   +TVR    +++ K+ E   EEL
Sbjct: 531 DVDDRNETLGKKIRDAQTEWIPYIAVVGEKEIESGKLAVTVRAESTQKEQKRVEMSAEEL 590

Query: 596 IKEIKEKTEGFPYKPRPLPLLLSKRPKFR 624
            + ++ + EG P+ P PLP LLS RP FR
Sbjct: 591 AERVRSECEGKPFMPLPLPKLLSLRPSFR 619


>sp|Q58597|SYT_METJA THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           Length = 620
           
 Score =  581 bits (1482), Expect = e-165
 Identities = 309/636 (48%), Positives = 427/636 (66%), Gaps = 30/636 (4%)

Query: 1   MRVLLIHSDYIEYEVKDKALKNPEPISEDMKRGRMEEVLVAFISVEKVDEKNPEEVSLKA 60
           M++LLIHSDY+E+E K+K     E  +E++K G+++E L  FI+VE+ DE NPE  ++ A
Sbjct: 1   MKMLLIHSDYLEFEAKEKTKIAEE--TENLK-GKLDECLACFIAVEREDENNPEGTAIGA 57

Query: 61  IEEISKVAEQVKAENVFVYPFAHLSSELAKPSVAMDILNRVYQGLKERGFNVGKAPFGYY 120
           +EEI KVA Q+K  N+ VYP+AHLSS+L+ P  A+ +L  +   LKERG+NV +APFG+Y
Sbjct: 58  VEEIEKVANQLKVNNIVVYPYAHLSSDLSSPETAVKVLKDIESILKERGYNVLRAPFGWY 117

Query: 121 KAFKISCKGHPLAELSRTIVPEEARVEEVPEALRKEEEELVSYWYILTPEGE-LIEVDK- 178
           KAFKISCKGHPL+ELSR IV +E + EE  E          S +Y+L PE E +IE+++ 
Sbjct: 118 KAFKISCKGHPLSELSRKIVAKEEKKEEGEE----------SKFYLLNPETEEIIELNEN 167

Query: 179 -FDFTGYENLRKFVNYEIAKNRIAEK-EPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRL 236
             +    E L     +E+      E  EPPHVK + E ++  YE  SDPG+ R+YPKG+L
Sbjct: 168 NINIIKDEELLALAKHELGIREHKEHDEPPHVKFIKEKDICSYEEASDPGHFRWYPKGKL 227

Query: 237 IKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIVLSGDKRYFLRFA 296
           ++ LL  YV   V+  GAM VETPIMYD  +PA+ ++ ++F  RQY    G+K   LRFA
Sbjct: 228 MRDLLADYVYNLVVNMGAMPVETPIMYDLGNPAIREHADKFGERQYRFRQGNKELMLRFA 287

Query: 297 ACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDI 356
           ACFGQFM+KKD  +  R LPL++YEL+ YSFR E+RGEL GL+RLR FTMPDMHT+  ++
Sbjct: 288 ACFGQFMMKKDMYLLPRYLPLKLYELSTYSFRYEQRGELVGLKRLRCFTMPDMHTVCLNL 347

Query: 357 EQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIRFTEDFWKEHKDFIVELVK----LIGKP 412
           EQA EEF+KQF   ++  + + L+   Y V  RFT+DF+ EH+D+  ++ K      GK 
Sbjct: 348 EQAMEEFEKQFWECLKTGDDLNLS---YSVIFRFTKDFFDEHRDWFFKIAKEYKNKYGKD 404

Query: 413 VLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLI 472
           V++E+  +R  Y++ K +   +D+L +     TVQIDVE+A+RF I  +   G E YP+I
Sbjct: 405 VILEILPKRKHYWVGKVDIAVIDSLGRPIENPTVQIDVESAKRFDIKVHTNEG-EIYPII 463

Query: 473 LHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGK 532
           LHCSP+G+IERV+  +LEK A    +G  PM P+WLSPIQVRVIPV+E + DYAL VA K
Sbjct: 464 LHCSPTGSIERVLCGLLEKAAIEAEKGNAPMLPVWLSPIQVRVIPVAERHYDYALKVAEK 523

Query: 533 LEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDG---KQYE 589
           L    IR D DD +E ++KKIR A KEW+PY+VV+G  E E+  +TV  RE     K Y+
Sbjct: 524 LRENNIRADFDDREESVSKKIRNAGKEWVPYVVVIGDEEMESDKLTVTIREKSTLKKPYK 583

Query: 590 TR--IEELIKEIKEKTEGFPYKPRPLPLLLSKRPKF 623
            +  ++ELI+ IK++T  +PY+P PLP+  S +PKF
Sbjct: 584 EKMTLDELIERIKKETANYPYRPLPLPIRCSLQPKF 619


>pir||D64449 threonine--tRNA ligase (EC 6.1.1.3) - Methanococcus jannaschii
           >gi|1591826|gb|AAB99201.1| (U67561) threonyl-tRNA
           synthetase (thrS) [Methanococcus jannaschii]
           Length = 624
           
 Score =  581 bits (1482), Expect = e-165
 Identities = 309/636 (48%), Positives = 427/636 (66%), Gaps = 30/636 (4%)

Query: 1   MRVLLIHSDYIEYEVKDKALKNPEPISEDMKRGRMEEVLVAFISVEKVDEKNPEEVSLKA 60
           M++LLIHSDY+E+E K+K     E  +E++K G+++E L  FI+VE+ DE NPE  ++ A
Sbjct: 5   MKMLLIHSDYLEFEAKEKTKIAEE--TENLK-GKLDECLACFIAVEREDENNPEGTAIGA 61

Query: 61  IEEISKVAEQVKAENVFVYPFAHLSSELAKPSVAMDILNRVYQGLKERGFNVGKAPFGYY 120
           +EEI KVA Q+K  N+ VYP+AHLSS+L+ P  A+ +L  +   LKERG+NV +APFG+Y
Sbjct: 62  VEEIEKVANQLKVNNIVVYPYAHLSSDLSSPETAVKVLKDIESILKERGYNVLRAPFGWY 121

Query: 121 KAFKISCKGHPLAELSRTIVPEEARVEEVPEALRKEEEELVSYWYILTPEGE-LIEVDK- 178
           KAFKISCKGHPL+ELSR IV +E + EE  E          S +Y+L PE E +IE+++ 
Sbjct: 122 KAFKISCKGHPLSELSRKIVAKEEKKEEGEE----------SKFYLLNPETEEIIELNEN 171

Query: 179 -FDFTGYENLRKFVNYEIAKNRIAEK-EPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRL 236
             +    E L     +E+      E  EPPHVK + E ++  YE  SDPG+ R+YPKG+L
Sbjct: 172 NINIIKDEELLALAKHELGIREHKEHDEPPHVKFIKEKDICSYEEASDPGHFRWYPKGKL 231

Query: 237 IKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIVLSGDKRYFLRFA 296
           ++ LL  YV   V+  GAM VETPIMYD  +PA+ ++ ++F  RQY    G+K   LRFA
Sbjct: 232 MRDLLADYVYNLVVNMGAMPVETPIMYDLGNPAIREHADKFGERQYRFRQGNKELMLRFA 291

Query: 297 ACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDI 356
           ACFGQFM+KKD  +  R LPL++YEL+ YSFR E+RGEL GL+RLR FTMPDMHT+  ++
Sbjct: 292 ACFGQFMMKKDMYLLPRYLPLKLYELSTYSFRYEQRGELVGLKRLRCFTMPDMHTVCLNL 351

Query: 357 EQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIRFTEDFWKEHKDFIVELVK----LIGKP 412
           EQA EEF+KQF   ++  + + L+   Y V  RFT+DF+ EH+D+  ++ K      GK 
Sbjct: 352 EQAMEEFEKQFWECLKTGDDLNLS---YSVIFRFTKDFFDEHRDWFFKIAKEYKNKYGKD 408

Query: 413 VLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLI 472
           V++E+  +R  Y++ K +   +D+L +     TVQIDVE+A+RF I  +   G E YP+I
Sbjct: 409 VILEILPKRKHYWVGKVDIAVIDSLGRPIENPTVQIDVESAKRFDIKVHTNEG-EIYPII 467

Query: 473 LHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGK 532
           LHCSP+G+IERV+  +LEK A    +G  PM P+WLSPIQVRVIPV+E + DYAL VA K
Sbjct: 468 LHCSPTGSIERVLCGLLEKAAIEAEKGNAPMLPVWLSPIQVRVIPVAERHYDYALKVAEK 527

Query: 533 LEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDG---KQYE 589
           L    IR D DD +E ++KKIR A KEW+PY+VV+G  E E+  +TV  RE     K Y+
Sbjct: 528 LRENNIRADFDDREESVSKKIRNAGKEWVPYVVVIGDEEMESDKLTVTIREKSTLKKPYK 587

Query: 590 TR--IEELIKEIKEKTEGFPYKPRPLPLLLSKRPKF 623
            +  ++ELI+ IK++T  +PY+P PLP+  S +PKF
Sbjct: 588 EKMTLDELIERIKKETANYPYRPLPLPIRCSLQPKF 623


>sp|O27504|SYT_METTH THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|7450856|pir||G69060 threonine--tRNA ligase (EC
           6.1.1.3) - Methanobacterium thermoautotrophicum (strain
           Delta H) >gi|2622569|gb|AAB85930.1| (AE000907)
           threonyl-tRNA synthetase [Methanobacterium
           thermoautotrophicum]
           Length = 605
           
 Score =  574 bits (1463), Expect = e-162
 Identities = 299/623 (47%), Positives = 415/623 (65%), Gaps = 18/623 (2%)

Query: 1   MRVLLIHSDYIEYEVKDKALKNPEPISEDMKRGRMEEVLVAFISVEKVDEKNPEEVSLKA 60
           MR+LLIHSDY++YE K+K     E I ED  +G   E LV F +VE  DE NPE V   A
Sbjct: 1   MRILLIHSDYLKYETKNKT-GIAEEIPEDKMQGDFRESLVVFTAVEAEDEDNPESVIENA 59

Query: 61  IEEISKVAEQVKAENVFVYPFAHLSSELAKPSVAMDILNRVYQGLKERGFNVGKAPFGYY 120
           + EI KV   VKAENV +YP+AHLSS L+ P  A+++L  +   L+  G +V + PFG+Y
Sbjct: 60  VNEIIKVFNDVKAENVVIYPYAHLSSSLSSPKTAVEVLEGMESALRSEGVDVSRVPFGWY 119

Query: 121 KAFKISCKGHPLAELSRTIVPEEARVEEVPEALRKEEEELVSYWYILTPEGELIEVDKFD 180
           KAFKISCKGHPL+ELSR+I P+  +VEE       E EE  S W+IL   GE ++   F+
Sbjct: 120 KAFKISCKGHPLSELSRSIRPQPPKVEE-------ESEE--SEWFIL-HRGETVKPGDFE 169

Query: 181 FTGYENLRKFVNYEIAKNRIAEKEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSL 240
           F    +L   V YE+ +   + +EPPHV+LM E  L DYEP +D G+LR+YP+GRLI+ L
Sbjct: 170 FKN-RDLENLVKYELGELESSGEEPPHVRLMREKGLADYEPSADVGHLRWYPRGRLIRDL 228

Query: 241 LEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIVLSGDKRYFLRFAACFG 300
           L  YV   V   GAM VETPIMYD E  A+  +  +F  RQY  +   K   LR+A CFG
Sbjct: 229 LADYVYMLVTSEGAMPVETPIMYDLEDEAIRVHAEKFGERQY-RMKNRKELMLRYACCFG 287

Query: 301 QFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAK 360
            F I  D+ ++++NLP  +YEL+ YSFR EK+GE+ GL+RLR FTMPD+HT+  D++Q+ 
Sbjct: 288 AFRILSDSFLTWKNLPASIYELSTYSFRLEKKGEVVGLKRLRGFTMPDLHTVCADLDQSL 347

Query: 361 EEFKKQFKLSMEVLEGVGLTPEDYEVAIRFTEDFWKEHKDFIVELVKLIGKPVLIEMWKQ 420
           EEF +Q ++ M   + + +   +YEV  R T DF++E+++++ E+   IGKPVL+E+   
Sbjct: 348 EEFARQVEMCMRTGQDLQV---NYEVIFRATADFYEEYREWVHEVADKIGKPVLLEILPS 404

Query: 421 RFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGA 480
           R  Y+I K +F  +D L +     TVQIDVE+ ERFGITY + + EE  P+ILHCSP+G+
Sbjct: 405 RKHYWIAKMDFAAIDYLGRPIENPTVQIDVESGERFGITYVNSDEEEVNPIILHCSPTGS 464

Query: 481 IERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRV 540
           IERV+ ++LEK A  M+E K PM PLWLSP QVRV+P++E +++YA  +  +L  A +R 
Sbjct: 465 IERVICSLLEKTAIEMDE-KPPMLPLWLSPTQVRVLPIAERHMEYASDLVSELIAADVRA 523

Query: 541 DVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYETRIEELIKEIK 600
           D+DD  E L KKIR A ++W+PY+VV+G  E E G +TV  RE G++ +  ++ELI+ I+
Sbjct: 524 DLDDRSETLGKKIRNAAQDWVPYVVVIGDSEME-GKLTVNVRETGEKLQMGLDELIERIR 582

Query: 601 EKTEGFPYKPRPLPLLLSKRPKF 623
            +TEG P++  PLP+ LS+R  F
Sbjct: 583 AETEGMPFRRLPLPVKLSERINF 605


>sp|P56881|SYT_THETH THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|6689424|emb|CAB65483.1| (AJ250953) threonyl-tRNA
           synthetase [Thermus thermophilus]
           Length = 659
           
 Score =  184 bits (462), Expect = 3e-45
 Identities = 131/396 (33%), Positives = 194/396 (48%), Gaps = 25/396 (6%)

Query: 203 KEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIM 262
           K+  H +L  E EL   +P    G + + PKG +++  L  ++ E+ +  G   V TP +
Sbjct: 249 KKRDHRRLGRELELFLIDPLVGKGLVLWLPKGNVVREELMAFMREEQVRRGYQLVTTPHI 308

Query: 263 YDFEHPALEKYL-----NRFPARQYIVLSGDKRYFLRFAACFGQFMIKKDAIISYRNLPL 317
              E      +      ++FP   +     ++ Y L+   C     I      SYR LPL
Sbjct: 309 GSLELYKTSGHYPYYAESQFPPISFKERGEEEEYLLKPMNCPHHIRIYAYRKRSYRELPL 368

Query: 318 RMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGV 377
           R+ E     +R EK GEL GL R+R FT  D H      E+ K EF     L ++V   +
Sbjct: 369 RLAEFGTV-YRYEKAGELLGLTRVRGFTQDDAHIFCTP-EEVKGEFLGVLDLVLKVFATL 426

Query: 378 GLTPEDYEVAIRFT--------EDFWKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKF 429
           GL      + +R          E  W   +  I E     G    +E     F+    K 
Sbjct: 427 GLKDYRARIGVRDPKSDKYVGDEAKWALAERQIEEAAAEAGLRYTVEEGDAAFYG--PKL 484

Query: 430 EFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYAIL 489
           +F   D L +   L T+Q+D    ERFG+TY  ++GEE  P++LH +P G++ER +  ++
Sbjct: 485 DFVVKDALGREWQLGTIQVDYNLPERFGLTYVGKDGEEHRPVMLHRAPFGSLERFIGILI 544

Query: 490 EKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDEDERL 549
           E  A          FPLWL+P+Q  V+PVSE+  DYA  VAG+L+ A +R + D   ER+
Sbjct: 545 EHFAG--------DFPLWLAPVQAVVVPVSEKQEDYAREVAGRLKEAGLRAEADTRPERM 596

Query: 550 NKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDG 585
             +IR AE + +PYI+VVG REK  G ++VRRR+ G
Sbjct: 597 QARIRDAEVQKVPYILVVGEREKAEGAVSVRRRKKG 632


>sp|P18255|SYT1_BACSU THREONYL-TRNA SYNTHETASE 1 (THREONINE--TRNA LIGASE) (THRRS)
           >gi|68516|pir||YSBST1 threonine--tRNA ligase (EC
           6.1.1.3) thrS [validated] - Bacillus subtilis
           >gi|143766|gb|AAA22864.1| (M36594) (thrSv) (EC 6.1.1.3)
           [Bacillus subtilis] >gi|1769999|emb|CAA99608.1| (Z75208)
           threonyl-tRNA-synthetase [Bacillus subtilis]
           >gi|2293284|gb|AAC00362.1| (AF008220) threonine tRNA
           synthetase [Bacillus subtilis]
           >gi|2635360|emb|CAB14855.1| (Z99118) threonyl-tRNA
           synthetase [Bacillus subtilis]
           Length = 643
           
 Score =  182 bits (458), Expect = 8e-45
 Identities = 127/407 (31%), Positives = 200/407 (48%), Gaps = 23/407 (5%)

Query: 203 KEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIM 262
           KE  H KL  E +L         G   + PKG  I+ ++E+Y+ +K I  G   V TP++
Sbjct: 242 KERDHRKLGKELKLFANSQKVGQGLPLWLPKGATIRRVIERYIVDKEISLGYEHVYTPVL 301

Query: 263 YDFEHPALEKYLNRFPARQYIVLSGDKRYF-LRFAACFGQFMIKKDAIISYRNLPLRMYE 321
              E      + + +    +  +  D     LR   C    MI K  I SYR LP+R+ E
Sbjct: 302 GSKELYETSGHWDHYQEGMFPPMEMDNETLVLRPMNCPHHMMIYKQDIHSYRELPIRIAE 361

Query: 322 LTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTP 381
           L     R E  G LSGL+R+R  T+ D H   +  +Q K+EF +  +L  +V E  GL+ 
Sbjct: 362 LGTMH-RYEMSGALSGLQRVRGMTLNDAHIFVRP-DQIKDEFIRTVRLIQDVYEDFGLSD 419

Query: 382 EDYEVAIRFTED---------FWKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFN 432
             + ++ R  ED          W + +  + E +  IG        +  F+    K +  
Sbjct: 420 YTFRLSYRDPEDTEKYFDDDEMWNKAQSMLKEAMDEIGHDYYEAEGEAAFYG--PKLDVQ 477

Query: 433 FVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYAILEKQ 492
               + K   LSTVQ+D    ERF +TY  E+G++  P+++H      +ER +  ++E+ 
Sbjct: 478 VKTAIGKEETLSTVQLDFLLPERFDLTYIGEDGKQHRPVVIHRGVVSTMERFVAFLIEEH 537

Query: 493 AKLMNEGKKPMFPLWLSPIQVRVIPVSEE-YLDYALYVAGKLEGAKIRVDVDDEDERLNK 551
                   K   P WL+P+Q +VIPVS   +LDYA  V  +L+   +RV+VD  DE++  
Sbjct: 538 --------KGALPTWLAPVQFQVIPVSPAVHLDYAKKVQERLQCEGLRVEVDSRDEKIGY 589

Query: 552 KIRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYETRIEELIKE 598
           KIR A+ + IPY++VVG +E ENG + VR+  +       ++E +K+
Sbjct: 590 KIREAQMQKIPYMLVVGDQEAENGAVNVRKYGEQNSETISLDEFVKK 636


>sp|P18256|SYT2_BACSU THREONYL-TRNA SYNTHETASE 2 (THREONINE--TRNA LIGASE) (THRRS)
           >gi|68515|pir||YSBST2 threonine--tRNA ligase (EC
           6.1.1.3) thrZ [validated] - Bacillus subtilis
           >gi|143764|gb|AAA22863.1| (M36593) threonyl-tRNA
           synthetase (thrS2) (EC 6.1.1.3) [Bacillus subtilis]
           >gi|2636292|emb|CAB15783.1| (Z99123) threonyl-tRNA
           synthetase [Bacillus subtilis]
           Length = 638
           
 Score =  177 bits (444), Expect = 4e-43
 Identities = 110/389 (28%), Positives = 202/389 (51%), Gaps = 26/389 (6%)

Query: 225 PGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIV 284
           PG   Y PKG+++++ LE++  E     G  EV TP M +        + + +    Y  
Sbjct: 263 PGMPFYLPKGQIVRNELERFSRELQTNAGYDEVRTPFMMNQRLWEQSGHWDHYRDNMYFS 322

Query: 285 LSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAF 344
              D R+ ++   C G  +I K+++ SYR+LP+RM E  +   R E  G L+G+ R+R F
Sbjct: 323 EVDDTRFAMKPMNCPGHMLIFKNSLYSYRDLPIRMAEFGQVH-RHEYSGALNGMLRVRTF 381

Query: 345 TMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIRFT-------EDFWKE 397
              D H   ++ +Q + E K+  +L  EV    G    +Y V +          +  W+ 
Sbjct: 382 CQDDAHIFVRE-DQIESEIKEAIRLIDEVYRTFGF---EYSVELSTRPEDSLGDDSLWEA 437

Query: 398 HKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFG 457
            +  +  +++ +G    I      F+    K +F+  D L ++   +T+Q+D +  E+F 
Sbjct: 438 SERALARVLEELGLSYEINEGDGAFYG--PKIDFHIKDALKRSHQCATIQLDFQMPEKFD 495

Query: 458 ITYYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIP 517
           +TY +E  E+  P+++H +  G+I+R    ++E             FP+WL+PIQV++IP
Sbjct: 496 LTYINELNEKVRPVVIHRAVFGSIDRFFGILIEHYGGA--------FPVWLAPIQVQIIP 547

Query: 518 VSEEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTI 577
           VS  +LDY   V  +L+ A IR  +D+ +E+L  KIR ++ + IPY++V+G  E++   +
Sbjct: 548 VSHVHLDYCRKVQAELKQAGIRAGIDERNEKLGYKIRESQVQKIPYVLVLGDHEEQENAV 607

Query: 578 TVRR----REDGKQYETRIEELIKEIKEK 602
            VRR    + +   ++T  ++L+K+++ +
Sbjct: 608 NVRRFGHQQNEHVPFQTFKDKLVKQVENR 636


>emb|CAB02510.1| (Z80360) Threonyl tRNA Synthetase [Bacillus subtilis]
           Length = 601
           
 Score =  177 bits (444), Expect = 4e-43
 Identities = 110/389 (28%), Positives = 202/389 (51%), Gaps = 26/389 (6%)

Query: 225 PGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIV 284
           PG   Y PKG+++++ LE++  E     G  EV TP M +        + + +    Y  
Sbjct: 226 PGMPFYLPKGQIVRNELERFSRELQTNAGYDEVRTPFMMNQRLWEQSGHWDHYRDNMYFS 285

Query: 285 LSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAF 344
              D R+ ++   C G  +I K+++ SYR+LP+RM E  +   R E  G L+G+ R+R F
Sbjct: 286 EVDDTRFAMKPMNCPGHMLIFKNSLYSYRDLPIRMAEFGQVH-RHEYSGALNGMLRVRTF 344

Query: 345 TMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIRFT-------EDFWKE 397
              D H   ++ +Q + E K+  +L  EV    G    +Y V +          +  W+ 
Sbjct: 345 CQDDAHIFVRE-DQIESEIKEAIRLIDEVYRTFGF---EYSVELSTRPEDSLGDDSLWEA 400

Query: 398 HKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFG 457
            +  +  +++ +G    I      F+    K +F+  D L ++   +T+Q+D +  E+F 
Sbjct: 401 SERALARVLEELGLSYEINEGDGAFYG--PKIDFHIKDALKRSHQCATIQLDFQMPEKFD 458

Query: 458 ITYYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIP 517
           +TY +E  E+  P+++H +  G+I+R    ++E             FP+WL+PIQV++IP
Sbjct: 459 LTYINELNEKVRPVVIHRAVFGSIDRFFGILIEHYGGA--------FPVWLAPIQVQIIP 510

Query: 518 VSEEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTI 577
           VS  +LDY   V  +L+ A IR  +D+ +E+L  KIR ++ + IPY++V+G  E++   +
Sbjct: 511 VSHVHLDYCRKVQAELKQAGIRAGIDERNEKLGYKIRESQVQKIPYVLVLGDHEEQENAV 570

Query: 578 TVRR----REDGKQYETRIEELIKEIKEK 602
            VRR    + +   ++T  ++L+K+++ +
Sbjct: 571 NVRRFGHQQNEHVPFQTFKDKLVKQVENR 599


>sp|Q55806|SYT_SYNY3 THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|7437520|pir||S76615 hypothetical protein -
           Synechocystis sp. (strain PCC 6803)
           >gi|1001722|dbj|BAA10559.1| (D64004) threonyl-tRNA
           synthetase [Synechocystis sp.]
           Length = 603
           
 Score =  176 bits (442), Expect = 6e-43
 Identities = 131/491 (26%), Positives = 238/491 (47%), Gaps = 47/491 (9%)

Query: 127 CKGHPLAELSRTIVPEEARVEEVPEALRKEEEELVSYWYILTPEGELIEVDKFDFTGYEN 186
           C G P  E +  I P+   +E V  A          YW     +    ++ +   T +E 
Sbjct: 134 CAG-PHLESTADINPKAIALESVAGA----------YW---RGDANKAQLQRIYGTAWET 179

Query: 187 LRKFVNYEIAKNRIAEKEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVT 246
             +   Y+  K    +++  H KL  E  L  +     PG   + PKG +I+++LE ++ 
Sbjct: 180 PEQLAEYQRRKEEALKRD--HRKLGKELGLFIFADPVGPGLPLWTPKGTIIRTILEDFLK 237

Query: 247 EKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIVLSGDKR-------YFLRFAACF 299
           ++ I+ G + V TP +   +      +  ++    + +++           + L+   C 
Sbjct: 238 QEQIKRGYLPVVTPHIARVDLFKQSGHWQKYQEDMFPMMAESPEEAAQEMGFVLKPMNCP 297

Query: 300 GQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQA 359
               I K  + SYR+LPLR+ E     +R E+ GEL GL R+R FT+ D H      +Q 
Sbjct: 298 FHIQIYKSELRSYRDLPLRLAEFGTV-YRYEQSGELGGLTRVRGFTVDDSHLFVTP-DQL 355

Query: 360 KEEFKKQFKLSMEVLEGVGLTPEDYEVAIRF----------TEDFWKEHKDFIVELVKLI 409
            EEF     L + V + + L  ++++  + F          +++ W++ +  I   V+ +
Sbjct: 356 DEEFLSVVDLILTVFKSLQL--KNFKARLSFRDPESDKYIGSDEAWEKAQGAIRRAVQEL 413

Query: 410 GKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKY 469
                    +  F+    K +F F D L++   L TVQ+D    ERF + Y   +G  + 
Sbjct: 414 EMDYFEAPGEAAFYG--PKLDFIFQDALEREWQLGTVQVDYNLPERFDLEYIAADGSRQR 471

Query: 470 PLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYV 529
           P+++H +P G++ER++  ++E+ A          FPLWL+PIQVR++ VS+E+L +A  +
Sbjct: 472 PVMIHRAPFGSLERLIGILIEEYAG--------DFPLWLAPIQVRLLAVSDEFLPFAQSI 523

Query: 530 AGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYE 589
             +++   +R +VD   +RL K IR AEK+ IP + V+GA+E E   + +R R  G+  E
Sbjct: 524 VQQMQSLGLRAEVDTSGDRLGKMIRNAEKQKIPVMAVIGAKEVEANALNIRTRASGELGE 583

Query: 590 TRIEELIKEIK 600
             + E++++++
Sbjct: 584 IPVTEVLEKLQ 594


>gb|AAG20043.1| (AE005084) threonyl-tRNA synthetase; ThrS [Halobacterium sp. NRC-1]
           Length = 650
           
 Score =  174 bits (436), Expect = 3e-42
 Identities = 125/424 (29%), Positives = 211/424 (49%), Gaps = 24/424 (5%)

Query: 194 EIAKNRIAEKEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYG 253
           E    R   KE  H KL  E +L      + PG   Y+P G+ +   L +YV     E G
Sbjct: 240 EYLARREEAKERDHRKLGREMDLFSIPDVTGPGLPLYHPNGKTVLRELSEYVRGLNSEMG 299

Query: 254 AMEVETPIMYDFEHPALEKYLNRFPARQYIVLSGDKRYFLRFAACFGQFMIKKDAIISYR 313
             EVETP ++  E      + + +    +++   D+ Y L+   C G   I  +   SYR
Sbjct: 300 YDEVETPHLFRTELWKQSGHYDNYVDDMFLLDVNDEEYGLKPMNCPGHATIFNEGSWSYR 359

Query: 314 NLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEV 373
           +LP+R +E  +  +R+E+RGELSGL R+ AFT+ D H  A+  +Q + E ++      EV
Sbjct: 360 DLPVRYFEDGKV-YRKEQRGELSGLSRVWAFTIDDGHVFAR-ADQIEAEVRRLMDTITEV 417

Query: 374 LEGVGLTPEDYEVAIRF-------TEDFWKEHKDFIVELVKLIGKPVLIEMWKQRFFYFI 426
           L+   L   DYEVA+         ++D W++ +  + E++   G    +E     F+   
Sbjct: 418 LDTFDL---DYEVALATRPEKSVGSDDIWEQSERQLREVLDQQGVDYDVEPGDGAFYG-- 472

Query: 427 LKFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIERVMY 486
            K +F F D L ++    TVQ+D    +RF + Y   + +   P+++H +  G+ ER   
Sbjct: 473 PKIDFGFEDALGRSWDGPTVQLDFNMPDRFDLEYTGSDNDAHQPVMIHRALYGSYERFFM 532

Query: 487 AILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDED 546
            ++E             FP WL+P QVR++PV+++ L YA  V  +L     RV+V+D D
Sbjct: 533 VLIEHY--------NGRFPTWLAPEQVRILPVTDDNLGYAHRVKNEL--GDYRVEVEDRD 582

Query: 547 ERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYETRIEELIKEIKEKTEGF 606
             + KKI++A  + +PY++VVG  E++   ++VR R++ +     + E    +  + +G 
Sbjct: 583 WTVGKKIQQAHDDNVPYMLVVGDDEEDADAVSVRDRQEREGKGVDLAEFRAHLDSEVDGK 642

Query: 607 PYKP 610
             +P
Sbjct: 643 RTEP 646


>pir||B75317 threonyl-tRNA synthetase - Deinococcus radiodurans (strain R1)
           >gi|6459875|gb|AAF11630.1|AE002044_3 (AE002044)
           threonyl-tRNA synthetase [Deinococcus radiodurans]
           Length = 649
           
 Score =  173 bits (434), Expect = 5e-42
 Identities = 127/412 (30%), Positives = 204/412 (48%), Gaps = 24/412 (5%)

Query: 203 KEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIM 262
           K   H KL  E EL   +P    G   + P G +++  L  ++ E+  + G   V TP +
Sbjct: 245 KRRDHRKLGKELELFTIDPLVGKGLPLWLPNGTVLREELTNFMKEQQFQRGYQGVVTPNI 304

Query: 263 YDFEHPALEKYLNRFPARQYIVLSGDKR-YFLRFAACFGQFMIKKDAIISYRNLPLRMYE 321
            + +      +   +   Q+  +  D+  Y L+   C     I      SYR+LP+R+ E
Sbjct: 305 GNLDLYRTSGHYPYYSESQFNPIQVDEEEYMLKPMNCPHHVRIYASKPRSYRDLPVRLAE 364

Query: 322 LTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTP 381
                +R E+ GEL+GL R+R FT  D H   +  +Q K EF     L++ VL+  G+T 
Sbjct: 365 FGTV-YRYEQSGELNGLTRVRGFTQDDAHIFCRP-DQLKREFLDVLDLTVLVLKTFGMTD 422

Query: 382 EDYEVAIRFTEDF--------WKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNF 433
             + V +R  E          W   +  I+E V+ +G P  IE     F+    K +F  
Sbjct: 423 VRFRVGVRDPESDKYVGDEQNWALAERQIIEAVEEVGLPYTIEPGDAAFYG--PKLDFVV 480

Query: 434 VDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYAILEKQA 493
            D L +   L T+Q+D    ERF I+Y  E+G+E  P+++H +P G+IER    ++E  A
Sbjct: 481 KDVLGREWQLGTIQVDYNLPERFDISYTGEDGQEHRPIMIHRAPFGSIERFTGILIEHYA 540

Query: 494 KLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKI 553
                     FPLWL+P QV +IP+++ +  YA  +  +L  A +R +VDD   R+  K+
Sbjct: 541 G--------DFPLWLAPRQVMIIPIADRHNAYAEELREELHRAGLRAEVDDSSNRMQAKV 592

Query: 554 RRAEKEWIPYIVVVGAREKENGTITVRRR--EDGKQYE-TRIEELIKEIKEK 602
           R AE   IP +++VG +E+E   ++VR R  E  K+ +  + +EL  E+ E+
Sbjct: 593 RDAELHKIPVMLIVGDKEQEAREVSVRERTGEGTKERKGVKFDELKAELLER 644


>dbj|BAB06860.1| (AP001517) threonyl-tRNA synthetase 1 [Bacillus halodurans]
           Length = 645
           
 Score =  171 bits (428), Expect = 3e-41
 Identities = 123/413 (29%), Positives = 202/413 (48%), Gaps = 23/413 (5%)

Query: 203 KEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIM 262
           KE  H KL  E  +         G   + PKG  I+ ++E+Y+ +K  + G   V TP++
Sbjct: 244 KERDHRKLGKELGIFALSQKVGQGLPLWLPKGATIRRIIERYIVDKEEKLGYQHVYTPVL 303

Query: 263 YDFEHPALEKYLNRFPARQYIVLSGD-KRYFLRFAACFGQFMIKKDAIISYRNLPLRMYE 321
              E      + + +    +  +  + +   LR   C    M+ K  + SYR LPLR+ E
Sbjct: 304 ASSELYKTSGHWDHYKDDMFPTMEMENEELVLRPMNCPHHMMVYKTEMRSYRQLPLRIAE 363

Query: 322 LTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTP 381
           L     R E  G +SGL+R+R  T+ D H   +  +Q K+EF +  +L   V E  GL  
Sbjct: 364 LG-LMHRYEMSGAVSGLQRVRGMTLNDAHIFCRP-DQIKDEFVRVVRLIQAVYEDFGLKN 421

Query: 382 EDYEVAIRFTED---------FWKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFN 432
             + ++ R  ED          W + +  + E +  + +    E   +  FY   K +  
Sbjct: 422 YSFRLSYRDPEDKEKYFDDDNMWNKAQGMLKEAMDEL-ELEYFEAEGEAAFYGP-KLDVQ 479

Query: 433 FVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYAILEKQ 492
               L K   LSTVQ+D    ERF +TY  E+G+   P+++H      +ER +  +LE+ 
Sbjct: 480 VRTALGKDETLSTVQLDFLLPERFDLTYVGEDGQPHRPVVVHRGVVSTMERFVAFLLEEY 539

Query: 493 AKLMNEGKKPMFPLWLSPIQVRVIPVSEE-YLDYALYVAGKLEGAKIRVDVDDEDERLNK 551
                   K  FP WL+P+QV+VIPVS E +L+YA  V   L+ A IRV++D+ DE++  
Sbjct: 540 --------KGAFPTWLAPVQVQVIPVSPEAHLEYAKNVQETLQQAGIRVEIDERDEKIGY 591

Query: 552 KIRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYETRIEELIKEIKEKTE 604
           KIR A+ + IPY++V+G +E E   + VR+  +       ++E ++ +  + +
Sbjct: 592 KIREAQMQKIPYMLVLGDKEVEANGVNVRKYGEKDSSSMGLDEFVRHVAREAK 644


>gb|AAK42622.1| Threonyl-tRNA synthetase (thrS) [Sulfolobus solfataricus]
           Length = 545
           
 Score =  165 bits (413), Expect = 2e-39
 Identities = 119/445 (26%), Positives = 223/445 (49%), Gaps = 28/445 (6%)

Query: 169 PEGELIEVDKFDFTGYENLRKFVNYEIAKNRIAEKEPPHVKLMLEHELVDYEPGSDPGNL 228
           P  + + +    F   E L+ ++++ + K     +E  H  +  + +L  +   +  G +
Sbjct: 107 PNEQYVRIRGVAFETEEQLKDYLSW-LEK----AEETDHRLIGEKLDLFSFHEEAGSGLV 161

Query: 229 RYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIVLSGD 288
            ++PKG+ I++ L  ++ E     G  EV T  ++  +   +  +   +  +  +     
Sbjct: 162 LFHPKGQTIRNELIAFMREINDSMGYQEVYTSHVFKTDIWKISGHYTLYRDKLIVFNMEG 221

Query: 289 KRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPD 348
             Y ++   C    +I K    +YR+LP+R  E   + +R EK+GEL GL R+R F   D
Sbjct: 222 DEYGVKPMNCPAHILIYKSKPRTYRDLPIRFSEFG-HVYRWEKKGELYGLLRVRGFVQDD 280

Query: 349 MHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIRF-------TEDFWKEHKDF 401
            H   ++ +Q +EE K     ++EV    G   +D +  +         +++ W++  + 
Sbjct: 281 GHIFLRE-DQLREEIKMLISKTVEVWHKFGFKDDDIKPYLSTRPDESIGSDELWEKATNA 339

Query: 402 IVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYY 461
           ++  ++  G    I+  K+  FY   K +F   D+L +   LST+Q+D    ERF + Y 
Sbjct: 340 LISALQESGLKFGIKE-KEGAFYGP-KIDFEIRDSLGRWWQLSTIQVDFNLPERFKLEYI 397

Query: 462 DENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEE 521
           D++G +K P+++H +  G+I+R +  +LE          K   P WLS +QVRV+P+++E
Sbjct: 398 DKDGIKKRPVMVHRAIYGSIDRFVAILLEHF--------KGKLPTWLSSVQVRVLPITDE 449

Query: 522 YLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRR 581
             +YA  V   +   +IR ++D   E L+K+I+ A  + +PYI++VG +E   GT+TVR 
Sbjct: 450 VNEYAEKVLNDMRKRRIRAEIDYAGETLSKRIKNAYDQGVPYILIVGKKEASEGTVTVRA 509

Query: 582 RED----GKQYETRIEELIKEIKEK 602
           R +      ++E  +E LI EI ++
Sbjct: 510 RGNIEVRNVKFEKFLELLITEIAQR 534


>sp|Q9WZJ9|SYT_THEMA THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|7437519|pir||G72339 threonine--tRNA ligase (EC
           6.1.1.3) - Thermotoga maritima  (strain MSB8)
           >gi|4981265|gb|AAD35821.1|AE001744_11 (AE001744)
           threonyl-tRNA synthetase [Thermotoga maritima]
           Length = 640
           
 Score =  163 bits (408), Expect = 6e-39
 Identities = 120/450 (26%), Positives = 216/450 (47%), Gaps = 31/450 (6%)

Query: 162 SYWYILTPEGELIEVDKFDFTGYENLRKFVNY-EIAKNRIAEKEPPHVKLMLEHELVDYE 220
           +YW        L  V    F   E+L  ++ + E A+ R   K  P ++L + +   +Y 
Sbjct: 201 AYWRGSEKNPMLTRVYGTAFAKKEDLDNYLKFLEEAQRRDHRKLGPQLELFMLN--TEYA 258

Query: 221 PGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPAR 280
           PG       + PKG ++ + L ++  E   E G  E+ TP++ + +   +  + + +   
Sbjct: 259 PGMP----FFLPKGVVVLNELMKFSRELHRERGYQEIFTPLIMNEQLWKISGHWDHYAEN 314

Query: 281 QYIVLSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRR 340
            Y +   ++RY ++   C G  ++ K   +SYR+LPLR +E  R   R E+ G L GL R
Sbjct: 315 MYFIEKDEERYAVKPMNCPGHILVYKSRTVSYRDLPLRFFEFGRVH-RYERSGVLHGLMR 373

Query: 341 LRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLT--------PEDYEVAIRFTE 392
           +R+FT  D H      +Q +EE      L   +    G T        PED+       E
Sbjct: 374 VRSFTQDDAHIFCTP-DQIEEEILGVLDLINTIYSQFGFTYRVELSTMPEDH----MGDE 428

Query: 393 DFWKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVEN 452
             W++    +   ++  G    +   +  F+    K +F+  D++ +    +T+Q+D   
Sbjct: 429 AIWEKATTALKNALERAGLSYKVNEGEGAFYG--PKIDFHIRDSIGREWQCATIQLDFMM 486

Query: 453 AERFGITYYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQ 512
            E+F +TY   + +E   +++H +  G++ER    ++E  A          FP WL+PIQ
Sbjct: 487 PEKFNVTYIGPDNKEHRAVMIHRAIYGSLERFFGILIEHFAGA--------FPTWLAPIQ 538

Query: 513 VRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREK 572
           V VIP+SE++ D A  VA ++     RV  D+  E L  +IR+A+ + IPY++++G +E 
Sbjct: 539 VAVIPISEKHNDGAEKVARRISQEGFRVFFDNRRETLGYRIRQAQTQKIPYMIIIGDKEL 598

Query: 573 ENGTITVRRREDGKQYETRIEELIKEIKEK 602
           E+G I+VR R   +  +   E  ++ ++ +
Sbjct: 599 ESGKISVRTRTGKEIKDVDPEHFVETLRNE 628


>sp|O05947|SYT_RICPR THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|7437518|pir||E71733 threonine--tRNA ligase (EC
           6.1.1.3) - Rickettsia prowazekii
           >gi|2073475|emb|CAA72469.1| (Y11780) threonyl-tRNA
           synthetase [Rickettsia prowazekii]
           >gi|3860783|emb|CAA14684.1| (AJ235270) THREONYL-TRNA
           SYNTHETASE (thrS) [Rickettsia prowazekii]
           Length = 635
           
 Score =  162 bits (407), Expect = 8e-39
 Identities = 119/415 (28%), Positives = 206/415 (48%), Gaps = 27/415 (6%)

Query: 201 AEKEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETP 260
           AEK   H K+  E +L  ++  +  G + ++ KG  I + +EQY+ +K+ + G +EV+TP
Sbjct: 238 AEKRD-HRKIGKELDLFHFQEEAQ-GMVFWHDKGWSIYNTIEQYIRKKIRKNGYIEVKTP 295

Query: 261 IMYDFEHPALEKYLNRFPARQYIVLSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMY 320
           ++ D        +  +F    + + + DK   L+   C     I K  I SYR+LPLRM 
Sbjct: 296 VLVDKSLWEASGHWAKFRCDMFTLETDDKTLALKPMNCPCHVQIFKQGIKSYRDLPLRMS 355

Query: 321 ELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLT 380
           E      R E  G L GL R+R+    D H    + EQ  +E  +  KL  EV +  G T
Sbjct: 356 EFG-LCHRNEASGALHGLMRVRSLVQDDAHIFCAE-EQITDETVRFCKLLTEVYKDFGFT 413

Query: 381 PEDYEVAIRFTE---------DFWKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEF 431
               ++ ++F++         + W + ++ +   ++  G    +   +  F+    K EF
Sbjct: 414 ----DIKVKFSDRSEICAGNDEVWDKAENALKTAIEKAGFIYTLNPGEAAFYG--PKIEF 467

Query: 432 NFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYAILEK 491
              D + +     T+Q+D    ER    Y   +GE+K P++LH +  G++ER +  ++E+
Sbjct: 468 VLTDAIGRQWQCGTLQMDFVLPERLDANYIAASGEKKRPVMLHRAILGSLERFIGILIEE 527

Query: 492 QAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDEDERLNK 551
            A     GK   FP+WL+P+QV +  ++ +  DYAL V   L    +R D++   +++N 
Sbjct: 528 YA-----GK---FPIWLAPVQVAIATITNDLNDYALEVQKTLIDNGVRTDINISPDKINY 579

Query: 552 KIRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYETRIEELIKEIKEKTEGF 606
           KIR    + IP I V+G +E+ N  +T+R+    +Q    IE+LI  IK++   +
Sbjct: 580 KIREFSNQKIPIIAVIGKQEQANKQVTIRKLGTIEQEILSIEQLIAMIKKENSNY 634


>sp|O67583|SYT_AQUAE THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|7437523|pir||F70444 threonine--tRNA ligase (EC
           6.1.1.3) - Aquifex aeolicus >gi|2984004|gb|AAC07549.1|
           (AE000750) threonyl-tRNA synthetase [Aquifex aeolicus]
           Length = 638
           
 Score =  161 bits (404), Expect = 2e-38
 Identities = 114/409 (27%), Positives = 202/409 (48%), Gaps = 24/409 (5%)

Query: 203 KEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIM 262
           K+  H +L  E E    +     G + + P+G + + +LE Y+ E+ ++ G   V TP +
Sbjct: 240 KKRDHRRLGKELEFFTIDDNVGAGLILWLPRGAIYRKVLEDYLREEHLKRGYQLVYTPHV 299

Query: 263 YDFEHPALEKYLNRFPARQYIVLSGDKR-YFLRFAACFGQFMIKKDAIISYRNLPLRMYE 321
              +      +L  +    +  +  D+  Y+++   C     I K    SY+ LPL+++E
Sbjct: 300 GKSKLWETSGHLECYKQNMFPSMKIDEEEYYVKPMNCPFHIAIYKSRTRSYKELPLKLFE 359

Query: 322 LTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGL-- 379
           L    +R E  G L GL R+R FT  D H +    EQ  +  ++    ++  L+  G   
Sbjct: 360 LGTV-YRYELSGVLHGLLRVRGFTQDDAHIVCTP-EQVNDVIRETLDFALSTLKDFGFNE 417

Query: 380 ------TPEDYEVAIRFTEDFWKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNF 433
                 T  +Y +    +++ W+  ++ + + ++ +G    I+     F+    K +   
Sbjct: 418 FKIYLSTRPEYSIG---SDEQWEVSQNALKKAIEDLGYEYEIDEGGGAFYG--PKIDVKI 472

Query: 434 VDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYAILEKQA 493
            D + +   LST+Q D    ERF +TY   + ++  P ++H +  G+IER    +LE  A
Sbjct: 473 RDAIGRMWQLSTIQFDFNLPERFDMTYVGPDNKKHRPYMIHRALLGSIERFTGILLEHYA 532

Query: 494 KLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKI 553
            L+        P+WLSP QV +IP+++ + +YA  V   L+   IR ++D  +ER+N KI
Sbjct: 533 GLL--------PIWLSPTQVMIIPIADRHHEYAKKVYEFLKENGIRAEMDLREERMNAKI 584

Query: 554 RRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYETRIEELIKEIKEK 602
           R AE + IP I+VVG RE +N T++VR +++G      + + +  IKEK
Sbjct: 585 RDAELKKIPVILVVGDREAQNNTVSVRTKKEGNLGSMELNKFLDWIKEK 633


>pir||A82479 threonyl-tRNA synthetase VCA0287 [imported] - Vibrio cholerae
           (group O1 strain N16961) >gi|9657684|gb|AAF96196.1|
           (AE004368) threonyl-tRNA synthetase [Vibrio cholerae]
           Length = 642
           
 Score =  160 bits (400), Expect = 5e-38
 Identities = 108/381 (28%), Positives = 187/381 (48%), Gaps = 17/381 (4%)

Query: 225 PGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIV 284
           PG + ++  G  I   LE ++ +K+ EYG  EV+ P+M D        + +++    +  
Sbjct: 262 PGMVFWHHNGWSIFRDLEIFIRQKLNEYGYQEVKGPLMMDRVLWERSGHWDKYADAMFTT 321

Query: 285 LSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAF 344
            S ++ Y ++   C G   I    + SYR+LPLRM E      R E  G L G+ R+R F
Sbjct: 322 SSENREYAIKPMNCPGHIQIFNQGLKSYRDLPLRMAEFGS-CHRNEPSGSLHGIMRVRGF 380

Query: 345 TMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIR-----FTEDFWKEHK 399
           T  D H    + +Q ++E     K+  +     G      +++ R      +++ W + +
Sbjct: 381 TQDDAHIFCTE-DQIQQEVTSCIKMVYDTYTTFGFQNIVVKLSTRPEKRVGSDEIWDKSE 439

Query: 400 DFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGIT 459
             +++ +K +  P  I+  +  F+    K EF   D LD+A    TVQ+D     R G T
Sbjct: 440 QALIDSLKAMDIPFEIQEGEGAFYG--PKIEFTLYDCLDRAWQCGTVQLDFNLPTRLGAT 497

Query: 460 YYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVS 519
           Y  E+ E   P+++H +  G++ER +  ++E+ A          FP WL+P Q  V+ ++
Sbjct: 498 YVGESNERLIPVMIHRAILGSLERFIGILIEEYAGF--------FPTWLAPEQAVVVNIT 549

Query: 520 EEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITV 579
           ++  DYA  VA KL+   IR   D  +E++  KIR    + +PY++V G +E E G I V
Sbjct: 550 DKQADYAHEVAQKLQKCGIRAKADLRNEKIGFKIREHTLKRVPYMLVCGDQEMEAGEIAV 609

Query: 580 RRREDGKQYETRIEELIKEIK 600
           R R+     + ++++ I  I+
Sbjct: 610 RTRKGKDLGKFKLDDFIAHIQ 630


>pir||H82878 threonyl-tRNA synthetase UU534 [imported] - Ureaplasma urealyticum
           >gi|6899538|gb|AAF30947.1|AE002152_6 (AE002152)
           threonyl-tRNA synthetase [Ureaplasma urealyticum]
           Length = 580
           
 Score =  157 bits (392), Expect = 4e-37
 Identities = 123/453 (27%), Positives = 214/453 (47%), Gaps = 29/453 (6%)

Query: 162 SYWYILTPEGELIEVDKFDFTGYENLRKFVNYEIAKNRIAEKEPPHVKLMLEHELVDYEP 221
           SYW       +LI +    F+  + L  ++     K+    KE  H K+  +  L  +  
Sbjct: 140 SYWRGDANNDQLIRIYGVAFSDQDQLDAYL-----KDLQERKERDHRKIGKDLNLFTFNN 194

Query: 222 GSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQ 281
            +  G   + P G +IK+ +++++ E   ++    V TPI+   +      + + +    
Sbjct: 195 LAGQGLPIWLPNGTIIKNQVQKFINEVEFQFNFDTVITPILGSIDLYKTSGHWDHYKDNI 254

Query: 282 YIVLSGDKRYF-LRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRR 340
           +  +  D     LR   C    ++  + + SYR+LP+R+ E +    R E  G L+G  R
Sbjct: 255 FSPVQIDNEILVLRPMTCPHHTLVYSNELRSYRSLPIRLSEHS-ILHRYESSGGLTGFER 313

Query: 341 LRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIRFTED------- 393
           +R   + D H   +  +Q + E    FK+  E  EG+G+   +  +++    D       
Sbjct: 314 VREMILEDCHVFCR-FDQIEHEVINAFKMIQEAQEGLGIKTFEIHLSLNDPNDKEKYYDD 372

Query: 394 --FWKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVE 451
              W++ ++ + +++K    P   EM  +  FY   K +F     L++   +ST+Q+D  
Sbjct: 373 PQMWEQSQNVLRKMLKDHNIPYK-EMVGEAAFYGP-KIDFQVKTVLNRIITVSTIQLDFL 430

Query: 452 NAERFGITYYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPI 511
              RF +TY +E+ E+  P+++H    G  ER++  +LE+         K + PLWLSPI
Sbjct: 431 LPNRFNLTYINESNEQSVPVMIHIGIIGTYERLLAILLEQ--------TKGILPLWLSPI 482

Query: 512 QVRVIPVSEE-YLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAR 570
           QV +IPV+E  + DY   +  KL    IR +VD  +ERL+KKIR A+ + IPY +V+G  
Sbjct: 483 QVVIIPVNENLHTDYVKELNIKLRKHLIRSNVDLRNERLSKKIREAQIQKIPYQIVIGDE 542

Query: 571 E-KENGTITVRRREDGKQYETRIEELIKEIKEK 602
           E K N  +T R     K     I + I  ++ K
Sbjct: 543 EIKNNKMVTYRCYGSEKTTTVSITDFINMLENK 575


>sp|O51662|SYT_BORBU THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|7437524|pir||G70189 threonine--tRNA ligase (EC
           6.1.1.3) thrZ - Lyme disease spirochete
           >gi|2688663|gb|AAC67076.1| (AE001172) threonyl-tRNA
           synthetase (thrZ) [Borrelia burgdorferi]
           Length = 581
           
 Score =  155 bits (388), Expect = 1e-36
 Identities = 130/479 (27%), Positives = 217/479 (45%), Gaps = 27/479 (5%)

Query: 128 KGHPLAELSRTIVPEEARVEEVPEALRKEEEELVSYWYILTPEGELIEVDKFDFTGYENL 187
           K H   +L R   P    + ++     K      +YW        L  +    +   + L
Sbjct: 114 KSHNFVDLCRG--PHVENMNKIDPKAFKLTSIAGAYWRGSEKNPMLTRIYGTLWNNEKEL 171

Query: 188 RKFVNYEIAKNRIAEKEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTE 247
           R ++N      R   K+  H KL  E +L        PG + ++P G  I++L+E +  E
Sbjct: 172 RSYLNL-----REEIKKRDHRKLGKELDLFSIHEEIGPGLVFFHPNGAKIRALIEDFWRE 226

Query: 248 KVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIVLSGDKR-YFLRFAACFGQFMIKK 306
           +  + G   + TP +          +L+ +    +  +  DK  Y+L+   C     I  
Sbjct: 227 EHSKNGYDILFTPHIGKSWLWQTSGHLDFYKDSMFEKIEMDKSDYYLKPMNCPFHIAIYN 286

Query: 307 DAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQ 366
               SYR+LP R  EL    +R EK G L G+ R R FT  D H +     Q  +E K+ 
Sbjct: 287 TGKHSYRDLPFRWAELGTV-YRYEKIGALHGMMRARGFTQDDAHIICTH-SQVLDEIKEV 344

Query: 367 FKLSMEVLEGVGLT-PEDY-----EVAIRFTEDFWKEHKDFIVELVKLIGKPVLIEMWKQ 420
            + ++ +    G + P+ Y     + ++    D W+     + E +     P  I+    
Sbjct: 345 LRFAIYMWSKFGFSNPKAYLSTKPDKSVGNDSD-WEMSLKVLEETLSDFEVPYEIDKGGG 403

Query: 421 RFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGA 480
            F+    K +   VD+L++   +ST+Q D    ERF +TY  E+G+EK P ++H +  G+
Sbjct: 404 AFYG--PKIDLKIVDSLEREWQMSTIQFDFNLPERFNMTYTAEDGKEKRPFMIHRALLGS 461

Query: 481 IERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRV 540
           IER    ++E             FPLWLSP+QV +IPV+    DYA+ V  K +   IR+
Sbjct: 462 IERFFGILVEHYGGA--------FPLWLSPVQVVIIPVNNIVEDYAIKVFNKFKNEGIRI 513

Query: 541 DVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYETRIEELIKEI 599
            +D+   R+N KIR  + + IPY+ ++G RE     I++R R + +    +++E +K I
Sbjct: 514 KLDNSSSRMNAKIREYQAKKIPYMFIIGEREATEERISIRTRTNEQINGMKLDEALKFI 572


>sp|Q9ZMV3|SYT_HELPJ THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|7437521|pir||G71972 threonine--tRNA ligase (EC
           6.1.1.3) - Helicobacter pylori  (strain J99)
           >gi|4154621|gb|AAD05692.1| (AE001450) THREONYL-TRNA
           SYNTHETASE [Helicobacter pylori J99]
           Length = 612
           
 Score =  153 bits (384), Expect = 4e-36
 Identities = 114/438 (26%), Positives = 210/438 (47%), Gaps = 25/438 (5%)

Query: 173 LIEVDKFDFTGYENLRKFV-NYEIAKNRIAEKEPPHVKLMLEHELVDYEPGSDPGNLRYY 231
           LI +    F   E L+ ++   E AK R       H KL +E  L  ++     G   + 
Sbjct: 190 LIRIYGIAFATKEGLKDYLFQIEEAKKR------DHRKLGVELGLFSFDDEIGAGLPLWL 243

Query: 232 PKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIVLSGDKRY 291
           PKG  ++  +E  +++ ++  G   V+ P +   +   +  + + +    Y     ++ Y
Sbjct: 244 PKGARLRKRIEDLLSQALLLRGYEPVKGPEILKSDVWKISGHYDNYKENMYFTTIDEQEY 303

Query: 292 FLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHT 351
            ++   C G   + + A+ SYR+LPLR YE      R EK G L GL R+R FT  D H 
Sbjct: 304 GIKPMNCVGHIKVYQSALHSYRDLPLRFYEYG-VVHRHEKSGVLHGLLRVREFTQDDAHI 362

Query: 352 LAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIRFTEDF-----WKEHKDFIVELV 406
                EQ + E       + ++++  G + E  E++ R  +       W++  + + E +
Sbjct: 363 FCS-FEQIQSEVSAILDFTHKIMQAFGFSYE-MELSTRPAKSIGDDKVWEKATNALKEAL 420

Query: 407 KLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGE 466
           K       I+     F+    K +    D L +     T+Q+D+   ERF + + +E   
Sbjct: 421 KEHRIDYKIDEGGGAFYG--PKIDIKITDALKRKWQCGTIQVDMNLPERFKLAFTNEYNH 478

Query: 467 EKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYA 526
            + P+++H +  G+ ER +         +++E     FP +++P Q+ +IP++EE+  +A
Sbjct: 479 AEQPVMIHRAILGSFERFI--------AILSEHFGGNFPFFVAPTQIALIPINEEHHVFA 530

Query: 527 LYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDGK 586
           L +   L+   I V+V D+++ LNKK+R AEK+ IP I+V+G  E E   +++R RE   
Sbjct: 531 LKLKEALKKCDIFVEVLDKNDSLNKKVRLAEKQKIPMILVLGNEEVETEILSIRDREKQA 590

Query: 587 QYETRIEELIKEIKEKTE 604
           QY+  ++E +  ++ K +
Sbjct: 591 QYKMPLKEFLNMVESKMQ 608


>sp|P56071|SYT_HELPY THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|7437522|pir||C64535 threonine--tRNA ligase (EC
           6.1.1.3) - Helicobacter pylori  (strain 26695)
           >gi|2313207|gb|AAD07192.1| (AE000534) threonyl-tRNA
           synthetase (thrS) [Helicobacter pylori 26695]
           Length = 612
           
 Score =  150 bits (376), Expect = 3e-35
 Identities = 113/438 (25%), Positives = 209/438 (46%), Gaps = 25/438 (5%)

Query: 173 LIEVDKFDFTGYENLRKFV-NYEIAKNRIAEKEPPHVKLMLEHELVDYEPGSDPGNLRYY 231
           LI +    F   E L+ ++   E AK R       H KL +E  L  ++     G   + 
Sbjct: 190 LIRIYGIAFATKEGLKDYLFQIEEAKKR------DHRKLGVELGLFSFDDEIGAGLPLWL 243

Query: 232 PKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIVLSGDKRY 291
           PKG  ++  +E  +++ ++  G   V+ P +   +   +  + + +    Y     ++ Y
Sbjct: 244 PKGARLRKRIEDLLSQALLLRGYEPVKGPEILKSDVWKISGHYDNYKENMYFTTIDEQEY 303

Query: 292 FLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHT 351
            ++   C G   + + A+ SYR+LPLR YE      R EK G L GL R+R FT  D H 
Sbjct: 304 GIKPMNCVGHIKVYQSALHSYRDLPLRFYEYG-VVHRHEKSGVLHGLLRVREFTQDDAHI 362

Query: 352 LAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIRFTEDF-----WKEHKDFIVELV 406
                EQ + E       + ++++    + E  E++ R  +       W++  + + E +
Sbjct: 363 FCS-FEQIQSEVSAILDFTHKIMQAFDFSYE-MELSTRPAKSIGDDKVWEKATNALKEAL 420

Query: 407 KLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGE 466
           K       I+     F+    K +    D L +     T+Q+D+   ERF + + +E   
Sbjct: 421 KEHRIDYKIDEGGGAFYG--PKIDIKITDALKRKWQCGTIQVDMNLPERFKLAFTNEYNH 478

Query: 467 EKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYA 526
            + P+++H +  G+ ER +         +++E     FP +++P Q+ +IP++EE+  +A
Sbjct: 479 AEQPVMIHRAILGSFERFI--------AILSEHFGGNFPFFVAPTQIALIPINEEHHVFA 530

Query: 527 LYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDGK 586
           L +   L+   I V+V D+++ LNKK+R AEK+ IP I+V+G  E E   +++R RE   
Sbjct: 531 LKLKEALKKRDIFVEVLDKNDSLNKKVRLAEKQKIPMILVLGNEEVETEILSIRDREKQD 590

Query: 587 QYETRIEELIKEIKEKTE 604
           QY+  ++E +  ++ K +
Sbjct: 591 QYKMPLKEFLNMVESKMQ 608


>sp|O83809|SYT_TREPA THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|7437525|pir||B71275 threonine--tRNA ligase (EC
           6.1.1.3) (thrS) - syphilis spirochete
           >gi|3323150|gb|AAC65804.1| (AE001254) threonyl-tRNA
           synthetase (thrS) [Treponema pallidum]
           Length = 592
           
 Score =  150 bits (374), Expect = 6e-35
 Identities = 130/472 (27%), Positives = 209/472 (43%), Gaps = 42/472 (8%)

Query: 122 AFKISCKGHPLAELSRTIVPEEARVEEVPEALRKEEEELVSYWYILTPEGELIEVDKFDF 181
           AF   C+G P  +  R I P   ++  +  A          YW       +L  +    +
Sbjct: 125 AFTDLCRG-PHVQSMRDINPHAFKLTSIAGA----------YWRGNERGPQLTRIYGTAW 173

Query: 182 TGYENLRKFVNYEI-AKNRIAEKEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSL 240
              E+L  ++  +  AK R   K  P + L    E        +PG + ++P+G  +   
Sbjct: 174 ESEEDLHTYLRMQDEAKRRDHRKLGPALGLFHLDE-------ENPGQVFWHPEGWTLYVA 226

Query: 241 LEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIVLSGDKRYF-LRFAACF 299
           ++QY+   + E G  EV TP +          + +++ A  Y+   G+KR F L+   C 
Sbjct: 227 IQQYLRRVMHEDGYAEVHTPFVMPQSLWERSGHWDKYRANMYLT-EGEKRSFALKPMNCP 285

Query: 300 GQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQA 359
           G   I K    SYR+LPLR+ E    + R E  G L G+ R+R F   D H    + + A
Sbjct: 286 GHVEIFKQKTRSYRDLPLRLSEFGSCT-RNEPSGSLHGVMRVRGFVQDDAHIFCTEAQIA 344

Query: 360 KEEFKKQFKLSMEVLEGVGLTPEDYEVAI------RFTEDF-WKEHKDFIVELVKLIGKP 412
            E   +  +L   V    G   E   V        R  +D  W   +  + E  +  G  
Sbjct: 345 SE-VTRFCRLLARVYADFGFAQEQIRVKFSTRPEQRIGDDATWDRAERALAEACEAAG-- 401

Query: 413 VLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVE--NAERFGITYYDENGEEKYP 470
           +  E       ++  K EF  +D L++     T+Q+D +  + ER    Y  E+ +   P
Sbjct: 402 LSYEHAPGEGAFYGPKLEFALIDTLEREWQCGTIQVDYQLPSCERLNAEYVGEDNQRHMP 461

Query: 471 LILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVA 530
           +ILH +  G++ER +  ++E             FP WL+P+Q  VIPV+  +L+YA +VA
Sbjct: 462 VILHRTVIGSLERFIGILIEHYGGA--------FPPWLAPVQAVVIPVAPAFLEYAQHVA 513

Query: 531 GKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRR 582
            +L    +RV  D   ER+N KIR A+ + +PY+++VG RE     + VR R
Sbjct: 514 RELCARSLRVQADVSAERMNAKIRTAQTQKVPYLLIVGERELRAQQVAVRPR 565


>pir||T51624 threonine--tRNA ligase (EC 6.1.1.3) [imported] - Arabidopsis
           thaliana >gi|3617770|emb|CAA74705.1| (Y14329)
           threonyl-tRNA synthetase [Arabidopsis thaliana]
           Length = 709
           
 Score =  149 bits (372), Expect = 1e-34
 Identities = 125/454 (27%), Positives = 210/454 (45%), Gaps = 31/454 (6%)

Query: 162 SYWYILTPEGELIEVDKFDFTGYENLRKFVNY-EIAKNRIAEKEPPHVKLMLEHELVDYE 220
           +YW        L  V    +   + L+K++ + E AK           +L   H+L    
Sbjct: 277 AYWKGDKDRESLQRVYGISYPDQKQLKKYLQFLEEAKKYDHRLLGQKQELFFSHQL---- 332

Query: 221 PGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPAR 280
               PG+  + P G  + + L  ++  +    G  EV TP MY+ E      + + +   
Sbjct: 333 ---SPGSYFFLPLGTRVYNRLMDFIKNQYWHRGYTEVITPNMYNMELWQTSGHADNYKDN 389

Query: 281 QYIVLSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRR 340
            +      + + L+   C G  +I +  + SYR LPLR+ +      R E  G LSGL R
Sbjct: 390 MFTFNIEKQEFGLKPMNCPGHCLIFQHRVRSYRELPLRLADFG-VLHRNEASGALSGLTR 448

Query: 341 LRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAI-----RFTEDF- 394
           +R F   D H      EQ K E +   +    V +  G T   YE+ +     ++  D  
Sbjct: 449 VRRFQQDDAHIFCTT-EQVKGEVQGVLEFIDYVYKVFGFT---YELKLSTRPEKYLGDLE 504

Query: 395 -WKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENA 453
            W + +  + E ++  GKP+++      F+    K +    D +++    +T+Q+D +  
Sbjct: 505 TWDKAEADLKEAIEAFGKPLVLNEGDGAFYG--PKIDITVSDAMNRKFQCATLQLDFQLP 562

Query: 454 ERFGITYYDENGEEKY-PLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQ 512
            RF + Y  E+  +K  P+++H +  G++ER M+AIL +  K    GK   +P W+SP Q
Sbjct: 563 IRFNLEYAAEDEAKKSRPVMIHRAVLGSVER-MFAILLEHYK----GK---WPFWISPRQ 614

Query: 513 VRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREK 572
             V P+SE+   YA  V  +++ A   VD D  D +++KK+R A+     YI+VVG  E 
Sbjct: 615 AIVCPISEKSQQYAEKVQKQIKDAGFYVDADLTDRKIDKKVREAQLAQYNYILVVGETEA 674

Query: 573 ENGTITVRRREDGKQYETRIEELIKEIKEKTEGF 606
             G ++VR R++       IE+L++E K KT  F
Sbjct: 675 ATGQVSVRVRDNAAHSVKSIEDLLEEFKAKTAEF 708


>pir||B81939 probable threonine--tRNA ligase (EC 6.1.1.3) NMA0929 [imported] -
           Neisseria meningitidis (group A strain Z2491)
           >gi|7379634|emb|CAB84201.1| (AL162754) putative
           threonyl-tRNA synthetase [Neisseria meningitidis Z2491]
           Length = 637
           
 Score =  148 bits (371), Expect = 1e-34
 Identities = 108/392 (27%), Positives = 192/392 (48%), Gaps = 19/392 (4%)

Query: 199 RIAEKEP-PHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEV 257
           RI E E   H KL  + +L   +  + PG + ++PKG  +  ++EQ++ +++   G  EV
Sbjct: 234 RIEEAEKRDHRKLGKQLDLFHLQDEA-PGMVFWHPKGWALWQVIEQHMRKELNAAGYKEV 292

Query: 258 ETPIMYDFEHPALEKYLNRFPARQYIVLSGDKRYFLRFAACFGQFMIKKDAIISYRNLPL 317
           +TP + D        +   +    ++  S  + Y ++   C G   I  + + SYR+LP+
Sbjct: 293 KTPQIMDKTFWEKSGHWENYKDNMFVTSSEKREYAVKPMNCPGHVQIFNNGLRSYRDLPM 352

Query: 318 RMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGV 377
           R+ E      R E  G L GL R+R F   D H    + +Q   E +   +L + + +  
Sbjct: 353 RLAEFGS-CHRNEPSGALHGLMRVRGFVQDDAHIFCTE-DQIVSEARAFNELLVRIYKQF 410

Query: 378 GLTPEDYEVAIR-----FTEDFWKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFN 432
           G      ++++R      ++D W + +  + E +   G     E+  +  FY   K E++
Sbjct: 411 GFHDVSVKLSLRPEQRAGSDDVWDKAEQGLREALTACGVE-WGELPGEGAFYGP-KIEYH 468

Query: 433 FVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYAILEKQ 492
             D L ++    T+Q+D    ER    Y  EN +   P++LH +  G++ER +  ++E  
Sbjct: 469 VRDALGRSWQCGTLQLDFVLPERLDAEYVTENNDRARPVMLHRAILGSLERFIGILIENH 528

Query: 493 AKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDEDERLNKK 552
           A          FPLWL+P+Q+ ++ ++E   DY   VA KL+ A  RV++D  +E++  K
Sbjct: 529 AG--------SFPLWLAPVQLVIMNITENQADYCREVAAKLQAAGFRVELDLRNEKIGYK 580

Query: 553 IRRAEKEWIPYIVVVGAREKENGTITVRRRED 584
           IR   +   PY +VVG +EK+   + VRR+ +
Sbjct: 581 IRDNSQYRFPYQIVVGDKEKQENKVAVRRKAE 612


>pir||E81167 threonyl-tRNA synthetase NMB0720 [imported] - Neisseria
           meningitidis (group B strain MD58)
           >gi|7225946|gb|AAF41133.1| (AE002426) threonyl-tRNA
           synthetase [Neisseria meningitidis MC58]
           Length = 637
           
 Score =  148 bits (369), Expect = 2e-34
 Identities = 107/392 (27%), Positives = 192/392 (48%), Gaps = 19/392 (4%)

Query: 199 RIAEKEP-PHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEV 257
           RI E E   H KL  + +L   +  + PG + ++PKG  +  ++EQ++ +++   G  EV
Sbjct: 234 RIEEAEKRDHRKLGKQLDLFHLQDEA-PGMVFWHPKGWALWQVIEQHMRKELNAAGYKEV 292

Query: 258 ETPIMYDFEHPALEKYLNRFPARQYIVLSGDKRYFLRFAACFGQFMIKKDAIISYRNLPL 317
           +TP + D        + + +    ++  S  + Y ++   C G   I  + + SYR+LP+
Sbjct: 293 KTPQIMDKTFWEKSGHWDNYKDNMFVTSSEKREYAVKPMNCPGHVQIFNNGLRSYRDLPM 352

Query: 318 RMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGV 377
           R+ E      R E  G L GL R+R F   D H    + +Q   E +   +L + + +  
Sbjct: 353 RLAEFGS-CHRNEPSGALHGLMRVRGFVQDDAHIFCTE-DQIVSEARAFNELLIRIYKQF 410

Query: 378 GLTPEDYEVAIR-----FTEDFWKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFN 432
           G      ++++R      ++D W + +  + E +   G     E+  +  FY   K E++
Sbjct: 411 GFHDVSVKLSLRPEKRAGSDDVWDKAEQGLREALTACGVE-WGELPGEGAFYGP-KIEYH 468

Query: 433 FVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYAILEKQ 492
             D L ++    T+Q+D    ER    Y  EN +   P++LH +  G++ER +  ++E  
Sbjct: 469 VRDALGRSWQCGTLQLDFVLPERLNAEYVTENNDRARPVMLHRAILGSLERFIGILIENH 528

Query: 493 AKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDEDERLNKK 552
           A          FPLWL+P+Q+ ++ ++E   DY   VA KL+ A  R ++D  +E++  K
Sbjct: 529 AG--------SFPLWLAPVQLVIMNITENQADYCREVAAKLQAAGFRAELDLRNEKIGYK 580

Query: 553 IRRAEKEWIPYIVVVGAREKENGTITVRRRED 584
           IR   +   PY +VVG +EK+   + VRR+ +
Sbjct: 581 IRDNSQYRFPYQIVVGDKEKQENKVAVRRKAE 612


>gb|AAF53166.1| (AE003635) CG5353 gene product [alt 1] [Drosophila melanogaster]
           >gi|7297922|gb|AAF53167.1| (AE003635) CG5353 gene
           product [alt 2] [Drosophila melanogaster]
           Length = 690
           
 Score =  147 bits (368), Expect = 3e-34
 Identities = 115/416 (27%), Positives = 199/416 (47%), Gaps = 40/416 (9%)

Query: 207 HVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFE 266
           H K+  E EL  +   S PG+  + P+G  I + L  ++  +  + G  EV +P +Y+ +
Sbjct: 292 HRKIGREQELFFFHELS-PGSCFFQPRGAHIYNTLMGFIKAEYRKRGFQEVISPNIYNAK 350

Query: 267 HPALEKYLNRFPARQYIVLSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYS 326
                 +   +    +   +  +++ L+   C G  +I  +   S+R LPLRM +     
Sbjct: 351 LWMTSGHWQHYAENMFSFEAEKEKFALKPMNCPGHCLIFDNRNRSWRELPLRMADFG-VL 409

Query: 327 FRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGV--------- 377
            R E  G L+GL R+R F   D H        A E+ K + K  +E L+ V         
Sbjct: 410 HRNELSGALTGLTRVRRFQQDDAHIFC-----APEQIKSEMKGCLEFLKYVYTIFGFSFQ 464

Query: 378 ---GLTPEDYEVAIRFTEDFWKEHKDFIVELVKLIGKPVLIEMWKQR---FFYFILKFEF 431
                 P++Y   +    + W + +  + E +   G P     WK+      ++  K + 
Sbjct: 465 LVLSTRPDNYLGEL----EQWNDAEKALAESLNEFGMP-----WKENPGDGAFYGPKIDI 515

Query: 432 NFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYAILEK 491
             +D L +A   +T+Q+D +   RF ++Y  ++GE+K P+I+H +  G++ER++  + E 
Sbjct: 516 TIMDALKRAHQCATIQLDFQLPIRFNLSYIADDGEKKRPVIIHRAILGSVERMIAILTEN 575

Query: 492 QAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVD-DEDERLN 550
            A     GK   +P WLSP QV V+PV   Y  YA  V  +L  A    + D D  + +N
Sbjct: 576 FA-----GK---WPFWLSPRQVMVVPVGPAYDQYAQSVRDQLHDAGFMSEADCDAGDTMN 627

Query: 551 KKIRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYETRIEELIKEIKEKTEGF 606
           KKIR A+     +I+VVG +E+ + T+ VR R++    E  + ELI ++++  + F
Sbjct: 628 KKIRNAQLAQFNFILVVGDKERSSNTVNVRTRDNKVHGEVSVAELITKLQKIRDEF 683


>sp|O07151|SYT_MYCLE THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|2193902|emb|CAB09620.1| (Z96801) ThrS [Mycobacterium
           leprae]
           Length = 702
           
 Score =  147 bits (368), Expect = 3e-34
 Identities = 118/424 (27%), Positives = 198/424 (45%), Gaps = 35/424 (8%)

Query: 207 HVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFE 266
           H KL +E +L  +      G   ++PKG +++  +E+Y   K IE G   V TP +   +
Sbjct: 280 HRKLGIELDLFSFPDEIGSGLAIFHPKGSIVRREMEEYSRRKHIEAGYQFVNTPHITKAQ 339

Query: 267 --HPA--LEKYLNR-FPARQYIVLSGD--------KRYFLRFAACFGQFMIKKDAIISYR 313
             H +  L+ Y    FP         D        + Y+L+   C    +I      SYR
Sbjct: 340 LFHTSGHLDWYAEGIFPPMHLDAEHNDDGTVRKPGQDYYLKPMNCPMHTLIFSSRGRSYR 399

Query: 314 NLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEV 373
            LPLR++E     +R EK G + GL R R FTM D H      EQ   E     +  +++
Sbjct: 400 ELPLRLFEFGTI-YRYEKSGVVHGLTRARGFTMDDSHIFCTR-EQLHCELASLLRFVLDL 457

Query: 374 LEGVGLTPEDYEVAIRFTEDF------WKEHKDFIVELVKLIGKPVLIEMWKQRFFYFIL 427
           L   GL     E++ +  E F      W+E    + E+ +    P++ +     F+    
Sbjct: 458 LGDYGLEDFYLELSTKDPEKFVGSEEIWEEATAALAEVAENSTLPLVPDPGGAAFYG--P 515

Query: 428 KFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYA 487
           K      D L ++  +ST+Q+D    ERF + Y   +G  + P+++H +  G+IER    
Sbjct: 516 KISVQVRDALGRSWQMSTIQVDFNFPERFALEYTSADGTRQRPVMIHRALFGSIERFFGI 575

Query: 488 ILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDEDE 547
           + E  A          FP WL+PIQV  IPV+ E++ Y   VA +L+   +R +VD  D+
Sbjct: 576 LTEHYAGA--------FPAWLAPIQVVGIPVTGEHVSYLEEVAAQLKSCGVRTEVDVSDD 627

Query: 548 RLNKKIRRAEKEWIPYIVVVGAREKENGTITV----RRREDGKQYETRIEELIKEIKEKT 603
           R+ KKI R   + +P++++ G R+   G+++     R + +G   ++ +E ++  I ++ 
Sbjct: 628 RMAKKIVRHTNQKVPFMLLAGDRDVRTGSVSFRFGDRTQINGVARDSAVEAIVCWIVDRE 687

Query: 604 EGFP 607
             FP
Sbjct: 688 NDFP 691


>dbj|BAA15486.1| (D90813) Threonine--tRNA ligase (EC 6.1.1.3) [Escherichia coli]
           Length = 628
           
 Score =  146 bits (366), Expect = 5e-34
 Identities = 104/383 (27%), Positives = 180/383 (46%), Gaps = 17/383 (4%)

Query: 225 PGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIV 284
           PG + ++  G  I   LE +V  K+ EY   EV+ P M D        + + +    +  
Sbjct: 247 PGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTT 306

Query: 285 LSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAF 344
            S ++ Y ++   C G   I    + SYR+LPLRM E      R E  G L GL R+R F
Sbjct: 307 SSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGS-CHRNEPSGSLHGLMRVRGF 365

Query: 345 TMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIR-----FTEDFWKEHK 399
           T  D H    + EQ ++E     +L  ++    G      +++ R      +++ W   +
Sbjct: 366 TQDDAHIFCTE-EQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAE 424

Query: 400 DFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGIT 459
             +   ++    P   ++ +  F+    K EF   D LD+A    TVQ+D     R   +
Sbjct: 425 ADLAVALEENNIPFEYQLGEGAFYG--PKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSAS 482

Query: 460 YYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVS 519
           Y  E+ E K P+++H +  G++ER +  + E+ A          FP WL+P+QV ++ ++
Sbjct: 483 YVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGF--------FPTWLAPVQVVIMNIT 534

Query: 520 EEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITV 579
           +   +Y   +  KL  A IRV  D  +E++  KIR      +PY++V G +E E+G + V
Sbjct: 535 DSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAV 594

Query: 580 RRREDGKQYETRIEELIKEIKEK 602
           R R         + E+I++++++
Sbjct: 595 RTRRGKDLGSMDVNEVIEKLQQE 617


>pdb|1EVK|A Chain A, Crystal Structure Of A Truncated Form Of Threonyl-Trna
           Synthetase With The Ligand Threonine
           >gi|9955216|pdb|1EVK|B Chain B, Crystal Structure Of A
           Truncated Form Of Threonyl-Trna Synthetase With The
           Ligand Threonine >gi|9955217|pdb|1EVL|A Chain A, Crystal
           Structure Of A Truncated Form Of Threonyl-Trna
           Synthetase With A Threonyl Adenylate Analog
           >gi|9955218|pdb|1EVL|B Chain B, Crystal Structure Of A
           Truncated Form Of Threonyl-Trna Synthetase With A
           Threonyl Adenylate Analog >gi|9955219|pdb|1EVL|C Chain
           C, Crystal Structure Of A Truncated Form Of
           Threonyl-Trna Synthetase With A Threonyl Adenylate
           Analog >gi|9955220|pdb|1EVL|D Chain D, Crystal Structure
           Of A Truncated Form Of Threonyl-Trna Synthetase With A
           Threonyl Adenylate Analog
           Length = 401
           
 Score =  146 bits (366), Expect = 5e-34
 Identities = 104/383 (27%), Positives = 180/383 (46%), Gaps = 17/383 (4%)

Query: 225 PGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIV 284
           PG + ++  G  I   LE +V  K+ EY   EV+ P M D        + + +    +  
Sbjct: 20  PGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTT 79

Query: 285 LSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAF 344
            S ++ Y ++   C G   I    + SYR+LPLRM E      R E  G L GL R+R F
Sbjct: 80  SSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGS-CHRNEPSGSLHGLMRVRGF 138

Query: 345 TMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIR-----FTEDFWKEHK 399
           T  D H    + EQ ++E     +L  ++    G      +++ R      +++ W   +
Sbjct: 139 TQDDAHIFCTE-EQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAE 197

Query: 400 DFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGIT 459
             +   ++    P   ++ +  F+    K EF   D LD+A    TVQ+D     R   +
Sbjct: 198 ADLAVALEENNIPFEYQLGEGAFYG--PKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSAS 255

Query: 460 YYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVS 519
           Y  E+ E K P+++H +  G++ER +  + E+ A          FP WL+P+QV ++ ++
Sbjct: 256 YVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGF--------FPTWLAPVQVVIMNIT 307

Query: 520 EEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITV 579
           +   +Y   +  KL  A IRV  D  +E++  KIR      +PY++V G +E E+G + V
Sbjct: 308 DSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAV 367

Query: 580 RRREDGKQYETRIEELIKEIKEK 602
           R R         + E+I++++++
Sbjct: 368 RTRRGKDLGSMDVNEVIEKLQQE 390


>sp|P00955|SYT_ECOLI THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|7428463|pir||SYECTT threonine--tRNA ligase (EC
           6.1.1.3) - Escherichia coli >gi|5107656|pdb|1QF6|A Chain
           A, Structure Of E. Coli Threonyl-Trna Synthetase
           Complexed With Its Cognate Trna
           >gi|1742811|dbj|BAA15498.1| (D90814) Threonine--tRNA
           ligase (EC 6.1.1.3) [Escherichia coli]
           >gi|1742818|dbj|BAA15504.1| (D90815) Threonine--tRNA
           ligase (EC 6.1.1.3) [Escherichia coli]
           >gi|1788013|gb|AAC74789.1| (AE000267) threonine tRNA
           synthetase [Escherichia coli K12]
           Length = 642
           
 Score =  146 bits (366), Expect = 5e-34
 Identities = 104/383 (27%), Positives = 180/383 (46%), Gaps = 17/383 (4%)

Query: 225 PGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIV 284
           PG + ++  G  I   LE +V  K+ EY   EV+ P M D        + + +    +  
Sbjct: 261 PGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTT 320

Query: 285 LSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAF 344
            S ++ Y ++   C G   I    + SYR+LPLRM E      R E  G L GL R+R F
Sbjct: 321 SSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGS-CHRNEPSGSLHGLMRVRGF 379

Query: 345 TMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIR-----FTEDFWKEHK 399
           T  D H    + EQ ++E     +L  ++    G      +++ R      +++ W   +
Sbjct: 380 TQDDAHIFCTE-EQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAE 438

Query: 400 DFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGIT 459
             +   ++    P   ++ +  F+    K EF   D LD+A    TVQ+D     R   +
Sbjct: 439 ADLAVALEENNIPFEYQLGEGAFYG--PKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSAS 496

Query: 460 YYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVS 519
           Y  E+ E K P+++H +  G++ER +  + E+ A          FP WL+P+QV ++ ++
Sbjct: 497 YVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGF--------FPTWLAPVQVVIMNIT 548

Query: 520 EEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITV 579
           +   +Y   +  KL  A IRV  D  +E++  KIR      +PY++V G +E E+G + V
Sbjct: 549 DSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAV 608

Query: 580 RRREDGKQYETRIEELIKEIKEK 602
           R R         + E+I++++++
Sbjct: 609 RTRRGKDLGSMDVNEVIEKLQQE 631


>emb|CAA23560.1| (V00291) threonyl-tRNA synthetase (thrS; EC 6.1.1.3) [Escherichia
           coli]
           Length = 642
           
 Score =  146 bits (366), Expect = 5e-34
 Identities = 104/383 (27%), Positives = 180/383 (46%), Gaps = 17/383 (4%)

Query: 225 PGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIV 284
           PG + ++  G  I   LE +V  K+ EY   EV+ P M D        + + +    +  
Sbjct: 261 PGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTT 320

Query: 285 LSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAF 344
            S ++ Y ++   C G   I    + SYR+LPLRM E      R E  G L GL R+R F
Sbjct: 321 SSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGS-CHRNEPSGSLHGLMRVRGF 379

Query: 345 TMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIR-----FTEDFWKEHK 399
           T  D H    + EQ ++E     +L  ++    G      +++ R      +++ W   +
Sbjct: 380 TQDDAHIFCTE-EQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAE 438

Query: 400 DFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGIT 459
             +   ++    P   ++ +  F+    K EF   D LD+A    TVQ+D     R   +
Sbjct: 439 ADLAVALEENNIPFEYQLGEGAFYG--PKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSAS 496

Query: 460 YYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVS 519
           Y  E+ E K P+++H +  G++ER +  + E+ A          FP WL+P+QV ++ ++
Sbjct: 497 YVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGF--------FPTWLAPVQVVIMNIT 548

Query: 520 EEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITV 579
           +   +Y   +  KL  A IRV  D  +E++  KIR      +PY++V G +E E+G + V
Sbjct: 549 DSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAV 608

Query: 580 RRREDGKQYETRIEELIKEIKEK 602
           R R         + E+I++++++
Sbjct: 609 RTRRGKDLGSMDVNEVIEKLQQE 631


>emb|CAB70933.1| (AL137778) threonine-tRNA synthetase [Streptomyces coelicolor
           A3(2)]
           Length = 658
           
 Score =  143 bits (356), Expect = 7e-33
 Identities = 113/395 (28%), Positives = 182/395 (45%), Gaps = 22/395 (5%)

Query: 201 AEKEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETP 260
           AEK   H KL  E +L         G   ++PKG +I+ ++E Y   +  E G   V TP
Sbjct: 255 AEKRD-HRKLGSELDLFSIPEQIGSGLAVFHPKGGIIRRVMEDYSRRRHEEEGYEFVYTP 313

Query: 261 IMYDFEHPALEKYLNRFPARQYIVLSGDKR--YFLRFAACFGQFMIKKDAIISYRNLPLR 318
                +      +L+ +    Y  +  D+   Y+L+   C    +I      SYR LPLR
Sbjct: 314 HATKGKLFETSGHLDWYADGMYPPMQLDEGVDYYLKPMNCPMHNLIFDARGRSYRELPLR 373

Query: 319 MYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVG 378
           ++E     +R EK G + GL R R FT  D H      EQ  EE  K     + +L   G
Sbjct: 374 LFEFGTV-YRYEKSGVVHGLTRARGFTQDDAHIYCTR-EQMSEELDKTLTFVLNLLRDYG 431

Query: 379 LTPEDYEVAIRFTEDF------WKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFN 432
           L     E++ +  E F      W+E  + + ++ +     ++ +     F+    K    
Sbjct: 432 LNDFYLELSTKDPEKFVGSDEAWEEATETLRQVAEKQNLELVADPGGAAFYG--PKISVQ 489

Query: 433 FVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYAILEKQ 492
             D + +   +ST+Q+D    ERF + Y   +G +  P+++H +  G+IER    +LE  
Sbjct: 490 ARDAIGRTWQMSTIQLDFNLPERFSLEYTAADGAKTRPVMIHRALFGSIERFFAVLLEHY 549

Query: 493 AKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDEDERLNKK 552
           A  M        P WL+P+Q   IPV + ++ Y    A +     +RVDVD   +R+ KK
Sbjct: 550 AGAM--------PPWLAPVQAVGIPVGDAHVQYLEEFAAEARRKGLRVDVDASSDRMQKK 601

Query: 553 IRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQ 587
           IR  +K+ +P++++VG  +   GT++ R R DG Q
Sbjct: 602 IRTQQKQKVPFMIIVGDEDMHGGTVSFRYR-DGSQ 635


>sp|P52709|SYTC_CAEEL PROBABLE THREONYL-TRNA SYNTHETASE, CYTOPLASMIC (THREONINE--TRNA
           LIGASE) (THRRS) >gi|7497557|pir||T19994 hypothetical
           protein C47D12.6 - Caenorhabditis elegans
           >gi|3875006|emb|CAA93762.1| (Z69902) predicted using
           Genefinder~Similarity to Human threonyl-tRNA synthetase
           (SW:SYTC_HUMAN), contains similarity to Pfam domain:
           PF00587 (tRNA synthetase class II (G, H, P, S and T)),
           Score=493.9, E-value=4e-145, N=1~cDNA EST EMBL:M89192
           comes fro>
           Length = 725
           
 Score =  142 bits (354), Expect = 1e-32
 Identities = 108/404 (26%), Positives = 193/404 (47%), Gaps = 27/404 (6%)

Query: 207 HVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFE 266
           H KL  EH+L  +   S PG+  +YPKG  I + L  ++ ++    G  EV TP MY+ +
Sbjct: 322 HRKLGKEHDLFFFHQLS-PGSAFWYPKGAHIYNKLVDFIRKQYRRRGFTEVITPNMYNKK 380

Query: 267 HPALEKYLNRFPARQYIVLSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYS 326
                 +   +    + +    + + L+   C G  ++      +Y  LP R  +     
Sbjct: 381 LWETSGHWQHYSEDMFKIEVEKEEFGLKPMNCPGHCLMFGHMPHTYNELPFRFADFG-VL 439

Query: 327 FRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGV-GLT----- 380
            R E  G L+GL R+R F   D H   +  +Q  EE K+         E V G T     
Sbjct: 440 HRNEMSGALTGLTRVRRFQQDDAHIFCRQ-DQISEEIKQCLDFLEYAYEKVFGFTFKLNL 498

Query: 381 ---PEDYEVAIRFTEDFWKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNL 437
              PE +   I    + W + +  +   +   G+  ++      F+    K +    D L
Sbjct: 499 STRPEGFLGNI----ETWDKAEADLTNALNASGRKWVLNPGDGAFYG--PKIDITIQDAL 552

Query: 438 DKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMN 497
            +    +T+Q+D +   +F ++Y+DE GE++ P+++H +  G++ER+   + E       
Sbjct: 553 KRNFQCATIQLDFQLPNQFDLSYFDEKGEKQRPVMIHRAVLGSVERMTAILTESYG---- 608

Query: 498 EGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDE-DERLNKKIRRA 556
            GK   +P WLSP Q ++I V E   DYA  V  ++  A   ++ ++   + +NK++R+A
Sbjct: 609 -GK---WPFWLSPRQCKIITVHESVRDYANDVKKQIFEAGFEIEYEENCGDTMNKQVRKA 664

Query: 557 EKEWIPYIVVVGAREKENGTITVRRREDGKQYETRIEELIKEIK 600
           +     +I+V+GA+EKENGT+ VR R++  + E  +++LI + +
Sbjct: 665 QLAQFNFILVIGAKEKENGTVNVRTRDNAVRGEVALDKLISKFR 708


>sp|O06200|SYT_MYCTU THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|7437528|pir||E70571 probable thrS protein -
           Mycobacterium tuberculosis (strain H37RV)
           >gi|2104299|emb|CAB08628.1| (Z95387) thrS [Mycobacterium
           tuberculosis]
           Length = 692
           
 Score =  139 bits (348), Expect = 6e-32
 Identities = 107/393 (27%), Positives = 182/393 (46%), Gaps = 31/393 (7%)

Query: 207 HVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFE 266
           H KL +E +L  +      G   ++PKG +++  LE Y   K  E G   V +P +   +
Sbjct: 270 HRKLGVELDLFSFPDEIGSGLAVFHPKGGIVRRELEDYSRRKHTEAGYQFVNSPHITKAQ 329

Query: 267 HPALEKYLNRFPARQYIVLSGD-------------KRYFLRFAACFGQFMIKKDAIISYR 313
                 +L+ +    +  +  D             + Y+L+   C    +I +    SYR
Sbjct: 330 LFHTSGHLDWYADGMFPPMHIDAEYNADGSLRKPGQDYYLKPMNCPMHCLIFRARGRSYR 389

Query: 314 NLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEV 373
            LPLR++E     +R EK G + GL R+R  TM D H      +Q ++E +   +  +++
Sbjct: 390 ELPLRLFEFGTV-YRYEKSGVVHGLTRVRGLTMDDAHIFCTR-DQMRDELRSLLRFVLDL 447

Query: 374 LEGVGLTPEDYEVAIRFTEDF------WKEHKDFIVELVKLIGKPVLIEMWKQRFFYFIL 427
           L   GLT    E++ +  E F      W+E    + E+    G  ++ +     F+    
Sbjct: 448 LADYGLTDFYLELSTKDPEKFVGAEEVWEEATTVLAEVGAESGLELVPDPGGAAFYG--P 505

Query: 428 KFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYA 487
           K      D L +   +ST+Q+D    ERFG+ Y   +G    P+++H +  G+IER    
Sbjct: 506 KISVQVKDALGRTWQMSTIQLDFNFPERFGLEYTAADGTRHRPVMIHRALFGSIERFFGI 565

Query: 488 ILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDEDE 547
           + E  A          FP WL+P+QV  IPV++E++ Y   VA +L+   +R +VD  D+
Sbjct: 566 LTEHYA--------GAFPAWLAPVQVVGIPVADEHVAYLEEVATQLKSHGVRAEVDASDD 617

Query: 548 RLNKKIRRAEKEWIPYIVVVGAREKENGTITVR 580
           R+ KKI       +P++V+ G R+   G ++ R
Sbjct: 618 RMAKKIVHHTNHKVPFMVLAGDRDVAAGAVSFR 650


>sp|P57225|SYT_BUCAI THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|10038808|dbj|BAB12843.1| (AP001118) threonyl-tRNA
           synthetase [Buchnera sp. APS]
           Length = 642
           
 Score =  139 bits (348), Expect = 6e-32
 Identities = 103/383 (26%), Positives = 180/383 (46%), Gaps = 17/383 (4%)

Query: 225 PGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIV 284
           PG + ++ KG +I + L+ +V  K+ EY   EV+TP++ D        + + +    +  
Sbjct: 261 PGMIFWHNKGWIIFNELQNFVRVKLKEYKYEEVKTPLLIDKLIWKQSGHWDNYKNAIFTT 320

Query: 285 LSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAF 344
           LS  + Y ++   C G   I    + SYR+LP+RM E      R E  G L GL R+R F
Sbjct: 321 LSEHREYCIKPMNCPGHVQIFNSRLKSYRDLPIRMAEFGS-CHRNEPSGSLHGLMRVRNF 379

Query: 345 TMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIR-----FTEDFWKEHK 399
           T  D H      EQ + E     K+  ++           +++ R      T+  W E +
Sbjct: 380 TQDDAHIFCTR-EQVRSEINDCIKMIYDLYSTFHFKKILVKLSTRPEKRIGTDSLWNESE 438

Query: 400 DFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGIT 459
             + ++  LI   +  E       ++  K EF   D+LD+     T+Q+D     R    
Sbjct: 439 KDLSDM--LIENHLSFEYQSGEGAFYGPKIEFILQDSLDRNWQCGTIQLDFYLPLRLSSF 496

Query: 460 YYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVS 519
           Y +E  E+K P+I+H +  G+IER +  ++E+ +  +        P WLSP+QV +I ++
Sbjct: 497 YINEKNEKKVPVIIHRAILGSIERFIGILIEECSGNL--------PTWLSPVQVVIISIT 548

Query: 520 EEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITV 579
           +    Y   +  K     IR++ D  +E++  KIR      IPYI++ G +E  +  I+V
Sbjct: 549 DISSGYVKELFKKFSDVNIRIECDLRNEKIGFKIREHTLRRIPYILICGEKESSSKKISV 608

Query: 580 RRREDGKQYETRIEELIKEIKEK 602
           R R+        ++  IK+++++
Sbjct: 609 RNRQGHNFGMIDVDFFIKKLQKE 631


>sp|O04630|SYTC_ARATH PROBABLE THREONYL-TRNA SYNTHETASE, CYTOPLASMIC (THREONINE--TRNA
           LIGASE) (THRRS) >gi|7437517|pir||T01763 threonine--tRNA
           ligase (EC 6.1.1.3) - Arabidopsis thaliana
           >gi|2191162|gb|AAB61048.1| (AF007270) Similar to
           threonyl-tRNA synthetase; coded for by A. thaliana cDNA
           R65376 [Arabidopsis thaliana]
           Length = 702
           
 Score =  139 bits (346), Expect = 1e-31
 Identities = 124/467 (26%), Positives = 210/467 (44%), Gaps = 44/467 (9%)

Query: 162 SYWYILTPEGELIEVDKFDFTGYENLRKFVNY-EIAKNRIAEKEPPHVKLMLEHELVDYE 220
           +YW        L  V    +   + L+K++ + E AK           +L   H+L    
Sbjct: 257 AYWKGDKDRESLQRVYGISYPDQKQLKKYLQFLEEAKKYDHRLLGQKQELFFSHQL---- 312

Query: 221 PGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPAR 280
               PG+  + P G  + + L  ++  +    G  EV TP MY+ E      + + +   
Sbjct: 313 ---SPGSYFFLPLGTRVYNRLMDFIKNQYWHRGYTEVITPNMYNMELWQTSGHADNYKDN 369

Query: 281 QYIVLSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRR 340
            +      + + L+   C G  +I +  + SYR LP+R+ +      R E  G LSGL R
Sbjct: 370 MFTFNIEKQEFGLKPMNCPGHCLIFQHRVRSYRELPMRLADFG-VLHRNEASGALSGLTR 428

Query: 341 LRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAI-----RFTEDF- 394
           +R F   D H      EQ K E +   +    V +  G T   YE+ +     ++  D  
Sbjct: 429 VRRFQQDDAHIFCTT-EQVKGEVQGVLEFIDYVYKVFGFT---YELKLSTRPEKYLGDLE 484

Query: 395 -WKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENA 453
            W + +  + E ++  GKP+++      F+    K +    D +++    +T+Q+D +  
Sbjct: 485 TWDKAEADLKEAIEAFGKPLVLNEGDGAFYG--PKIDITVSDAMNRKFQCATLQLDFQLP 542

Query: 454 ERFGITYYDENGEEKY-PLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQ 512
            RF + Y  E+  +K  P+++H +  G++ER M+AIL +  K    GK   +P W+SP Q
Sbjct: 543 IRFNLEYAAEDEAKKSRPVMIHRAVLGSVER-MFAILLEHYK----GK---WPFWISPRQ 594

Query: 513 VRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDEDERLNKK-------------IRRAEKE 559
             V P+SE+   YA  V  +++ A   VD D  D +++KK             +R A+  
Sbjct: 595 AIVCPISEKSQQYAEKVQKQIKDAGFYVDADLTDRKIDKKVNDFGSCSKFCSVVREAQLA 654

Query: 560 WIPYIVVVGAREKENGTITVRRREDGKQYETRIEELIKEIKEKTEGF 606
              YI+VVG  E   G ++VR R++       IE+L++E K KT  F
Sbjct: 655 QYNYILVVGETEAATGQVSVRVRDNAAHSVKSIEDLLEEFKAKTAEF 701


>sp|Q9Z7A0|SYT_CHLPN THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|7437526|pir||G72034 threonine--tRNA ligase (EC
           6.1.1.3) CP1065 [similarity] - Chlamydophila pneumoniae
           (strains CWL029 and AR39) >gi|4377117|gb|AAD18944.1|
           (AE001661) Threonyl tRNA Synthetase [Chlamydophila
           pneumoniae CWL029] >gi|7189978|gb|AAF38837.1| (AE002263)
           threonyl-tRNA synthetase [Chlamydophila pneumoniae AR39]
           >gi|8979180|dbj|BAA99014.1| (AP002548) threonyl tRNA
           synthetase [Chlamydophila pneumoniae J138]
           Length = 635
           
 Score =  138 bits (343), Expect = 2e-31
 Identities = 102/386 (26%), Positives = 181/386 (46%), Gaps = 19/386 (4%)

Query: 223 SDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQY 282
           S PG   ++P+G ++   L +Y  +     G  E+ TP + + +   +  + + + A  Y
Sbjct: 253 SSPGMPFFHPRGMIVWDALIRYWKQLHTAAGYKEILTPQLMNRQLWEVSGHWDNYKANMY 312

Query: 283 IVLSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLR 342
            +   D+ Y ++   C G  +  K  + SY+  PLR+ E+  +  R+E  G LSGL R+R
Sbjct: 313 TLQIDDEDYAIKPMNCPGCMLYYKTRLHSYKEFPLRVAEVG-HVHRQEASGALSGLMRVR 371

Query: 343 AFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIRFTED------FWK 396
           AF   D H      EQ +EE     +L   +    GL     E++ R  +D       W+
Sbjct: 372 AFHQDDAHVFLTP-EQVEEETLNILQLVSTLYGTFGLEYH-LELSTRPEKDTIGDDSLWE 429

Query: 397 EHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERF 456
              D +   +   G P ++   +  F+    K + +  D + +     T+Q+D+   ERF
Sbjct: 430 LATDALNRALVQSGTPFIVRPGEGAFYG--PKIDIHVKDAIQRTWQCGTIQLDMFLPERF 487

Query: 457 GITYYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVI 516
            + Y    G +  P++LH +  G+IER +  ++E          K  FPLWLSP QVR+I
Sbjct: 488 ELEYTTAQGTKSVPVMLHRALFGSIERFLGILIENF--------KGRFPLWLSPEQVRII 539

Query: 517 PVSEEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGT 576
            V++ ++  A  +    +   + V +DD  E ++KKIR A+   + Y++ +G  E     
Sbjct: 540 TVADRHIPRAKELEEAWKRLGLVVTLDDSSESVSKKIRNAQNMQVNYMITLGDHEINENV 599

Query: 577 ITVRRREDGKQYETRIEELIKEIKEK 602
           + VR R++    +  +E  +  I E+
Sbjct: 600 LAVRTRDNRVINDVSVERFLNTILEE 625


>sp|O84585|SYT_CHLTR THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|6578108|gb|AAC68183.2| (AE001328) Threonyl tRNA
           Synthetase [Chlamydia trachomatis]
           Length = 635
           
 Score =  138 bits (343), Expect = 2e-31
 Identities = 102/389 (26%), Positives = 177/389 (45%), Gaps = 23/389 (5%)

Query: 230 YYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIVLSGDK 289
           ++P+G ++ + L  Y        G  +++TP + + E   +  +   +    Y +   ++
Sbjct: 260 FHPRGMVVWNALVDYWKRLHQRAGYQQIQTPQLMNRELWEISGHWENYKENMYTLTVDEE 319

Query: 290 RYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDM 349
            Y ++   C G  +  K  + SYR  PLR+ E+  +  R E  G LSGL R+R F   D 
Sbjct: 320 DYAIKPMNCPGCMLYYKTQLHSYREFPLRIAEIG-HVHRHELSGALSGLMRVRTFHQDDA 378

Query: 350 HTLAKDIEQAKEEFKKQFKLSMEVLEGVGLT--------PEDYEVAIRFTEDFWKEHKDF 401
           H      EQ +EE      L  E+    GL         PE   +    ++D W+     
Sbjct: 379 HVFLTP-EQVEEETLNILNLVSELYGTFGLEYHLELSTRPEQGTIG---SDDLWELATKA 434

Query: 402 IVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYY 461
           +   +    KP +I   +  F+    K + +  D +++     T+Q+D+   ERF + Y 
Sbjct: 435 LKRALVKSQKPFIISPGEGAFYG--PKIDIHVKDAINRTWQCGTIQLDMFLPERFDLKYT 492

Query: 462 DENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEE 521
           +  GE+  P++LH +  G+IER +  ++E          K  FPLWLSP  VR+I V++ 
Sbjct: 493 NAQGEKSTPIMLHRALFGSIERFLGILIEHF--------KGRFPLWLSPEHVRIITVADR 544

Query: 522 YLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRR 581
           +   A  +A       I V VD  +E ++KKIR A+   + Y++ +G +E E   + VR 
Sbjct: 545 HEARAQELAKHFSQMGIIVSVDSSNESVSKKIRNAQNMQVNYMITIGDKELETHLLAVRT 604

Query: 582 REDGKQYETRIEELIKEIKEKTEGFPYKP 610
           R++    +  +E+    I E+       P
Sbjct: 605 RDNRVLNDIAVEQFSHVILEELRSLSLTP 633


>pir||G71497 threonine--tRNA ligase (EC 6.1.1.3) - Chlamydia trachomatis
           (serotype D, strain UW3/Cx)
           Length = 660
           
 Score =  138 bits (343), Expect = 2e-31
 Identities = 102/389 (26%), Positives = 177/389 (45%), Gaps = 23/389 (5%)

Query: 230 YYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIVLSGDK 289
           ++P+G ++ + L  Y        G  +++TP + + E   +  +   +    Y +   ++
Sbjct: 285 FHPRGMVVWNALVDYWKRLHQRAGYQQIQTPQLMNRELWEISGHWENYKENMYTLTVDEE 344

Query: 290 RYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDM 349
            Y ++   C G  +  K  + SYR  PLR+ E+  +  R E  G LSGL R+R F   D 
Sbjct: 345 DYAIKPMNCPGCMLYYKTQLHSYREFPLRIAEIG-HVHRHELSGALSGLMRVRTFHQDDA 403

Query: 350 HTLAKDIEQAKEEFKKQFKLSMEVLEGVGLT--------PEDYEVAIRFTEDFWKEHKDF 401
           H      EQ +EE      L  E+    GL         PE   +    ++D W+     
Sbjct: 404 HVFLTP-EQVEEETLNILNLVSELYGTFGLEYHLELSTRPEQGTIG---SDDLWELATKA 459

Query: 402 IVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYY 461
           +   +    KP +I   +  F+    K + +  D +++     T+Q+D+   ERF + Y 
Sbjct: 460 LKRALVKSQKPFIISPGEGAFYG--PKIDIHVKDAINRTWQCGTIQLDMFLPERFDLKYT 517

Query: 462 DENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEE 521
           +  GE+  P++LH +  G+IER +  ++E          K  FPLWLSP  VR+I V++ 
Sbjct: 518 NAQGEKSTPIMLHRALFGSIERFLGILIEHF--------KGRFPLWLSPEHVRIITVADR 569

Query: 522 YLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRR 581
           +   A  +A       I V VD  +E ++KKIR A+   + Y++ +G +E E   + VR 
Sbjct: 570 HEARAQELAKHFSQMGIIVSVDSSNESVSKKIRNAQNMQVNYMITIGDKELETHLLAVRT 629

Query: 582 REDGKQYETRIEELIKEIKEKTEGFPYKP 610
           R++    +  +E+    I E+       P
Sbjct: 630 RDNRVLNDIAVEQFSHVILEELRSLSLTP 658


>sp|P47615|SYT_MYCGE THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|1361863|pir||E64241 threonine--tRNA ligase (EC
           6.1.1.3) - Mycoplasma genitalium
           >gi|3844963|gb|AAC71602.1| (U39719) threonyl-tRNA
           synthetase (thrS) [Mycoplasma genitalium]
           Length = 564
           
 Score =  137 bits (342), Expect = 3e-31
 Identities = 107/392 (27%), Positives = 185/392 (46%), Gaps = 23/392 (5%)

Query: 194 EIAKNRIAEKEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYG 253
           ++ K      +  H  L  + EL  ++P    G   +  KG  +++++  +V  + + +G
Sbjct: 155 QLIKENEERLKKDHRSLGKQLELFSFDPLIGAGLPIWLAKGTTLRNIIGNFVHHQQLLFG 214

Query: 254 AMEVETPIMYDFEHPALEKYLNRFPARQYIVLSGDKR-YFLRFAACFGQFMIKKDAIISY 312
              V +P++ + E   +  +   +    +  +  D +   LR   C    +I K    SY
Sbjct: 215 FNTVCSPVLANIELFKISGHYQHYKEDMFPAIKLDSQAMMLRPMTCPHHCLIFKQKRYSY 274

Query: 313 RNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSME 372
           + +P R  E      R E  G L GL R+R  T+ D H   +  +Q K E K  F L  +
Sbjct: 275 KKMPQRFSE-DSILHRFEASGGLIGLERVRCMTLLDNHIFCR-ADQIKSEIKNAFNLIQK 332

Query: 373 V-------LEGVGLTPEDYEVAIRFTED--FWKEHKDFIVELVKLIGKPVLIEMWKQRFF 423
           V        + + L+  D +   +F ++   W+E +  +  ++K +      E+    F+
Sbjct: 333 VNKKFGFIFDRIDLSLHDPKNQSKFIDNPGLWRESESQMENVLKDLNIQYQKEIGAAAFY 392

Query: 424 YFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIER 483
               K +F F     K   ++T+Q+D    E+F +TY D+    K P+I+H    G  ER
Sbjct: 393 G--PKIDFQFKTIFKKMITIATIQLDFLLPEKFDLTYIDKKNTLKKPVIIHVGIIGTYER 450

Query: 484 VMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVS-EEYLDYALYVAGKLEGAKIRVDV 542
            + A+LEK +          FPLWL+P+Q  +IPV+ +++L  A  +  KL    IRV++
Sbjct: 451 FIAALLEKTS--------GNFPLWLAPVQAVIIPVNIQKHLKAAKKLYNKLLKENIRVNL 502

Query: 543 DDEDERLNKKIRRAEKEWIPYIVVVGAREKEN 574
           DD  +RL KK+R+A  E IP  ++VG +E EN
Sbjct: 503 DDNQDRLAKKVRQAIIEKIPLQLIVGDKEIEN 534


>sp|P75225|SYT_MYCPN THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|2146662|pir||S73615 threonine--tRNA ligase (EC
           6.1.1.3) thrSv - Mycoplasma pneumoniae (strain ATCC
           29342) >gi|1673960|gb|AAB95937.1| (AE000027)
           threonyl-tRNA synthetase [Mycoplasma pneumoniae]
           Length = 564
           
 Score =  137 bits (342), Expect = 3e-31
 Identities = 109/399 (27%), Positives = 188/399 (46%), Gaps = 24/399 (6%)

Query: 215 ELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYL 274
           E+  ++P    G   +  KG ++K ++  +V  + + +G   V +P++ + E   +  + 
Sbjct: 176 EIFTFDPLVGAGFPIWLEKGAVLKKIIGDFVHYQQLMFGFKTVSSPVLANLELYKISGHY 235

Query: 275 NRFPARQY-IVLSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRG 333
             +    +  V   ++   LR   C    +I K    SY+ LP R  E      R E  G
Sbjct: 236 VHYSEDMFPSVKLENQMMMLRPMTCPHHCLIFKHKRRSYKELPQRFCE-DSILHRFEASG 294

Query: 334 ELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIRF--- 390
            L+GL R+R  T+ D H   +  +Q K E K  FKL   V    G + +  ++A+     
Sbjct: 295 GLTGLERVRCMTLLDNHIFCRT-DQIKAEIKNAFKLIQTVNNKFGFSFDRIDLALHDPNN 353

Query: 391 ------TEDFWKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALS 444
                  +  W   +  I  + K +  P  I++    F+    K +F F   L+K   ++
Sbjct: 354 KAKFIDNDQLWANSESQIESVFKELNVPYKIDVGAAAFYG--PKIDFQFKTALNKMITIA 411

Query: 445 TVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMF 504
           T+Q+D    ERF + Y+DE    + P+I+H    G  ER + A+LEK       G     
Sbjct: 412 TIQLDFLLPERFELRYFDEQSNAQTPVIIHVGIVGTYERFIAALLEK-----THGN---L 463

Query: 505 PLWLSPIQVRVIPVS-EEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPY 563
           PLW++P+QV VIPV+ +++   A  +  KL    IRV +D+ ++RL KK+R A    IP 
Sbjct: 464 PLWMAPVQVVVIPVNIDKHEKAAKKLYQKLLKENIRVSLDESEDRLGKKVRTAIVNKIPL 523

Query: 564 IVVVGAREKENGT-ITVRRREDGKQYETRIEELIKEIKE 601
            ++VG +E ++ T IT R  +  K  +      +K++++
Sbjct: 524 QIIVGDKEMQDLTRITCRGFKGEKVQKLYWANFVKKVRK 562


>pir||F83303 threonyl-tRNA synthetase PA2744 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9948822|gb|AAG06132.1|AE004702_9
           (AE004702) threonyl-tRNA synthetase [Pseudomonas
           aeruginosa]
           Length = 640
           
 Score =  136 bits (339), Expect = 7e-31
 Identities = 103/382 (26%), Positives = 175/382 (44%), Gaps = 20/382 (5%)

Query: 225 PGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIV 284
           PG + ++P G  +  +LEQY+ +   ++G +EV TP + D        + + +    +  
Sbjct: 260 PGMVFWHPNGWSVYQVLEQYMRKVQRDHGYVEVRTPQVVDRILWERSGHWSNYAENMFTT 319

Query: 285 LSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAF 344
            S  + Y ++   C     I    + SYR+LPLR+ E      R E  G L G+ R+R F
Sbjct: 320 SSESRDYAVKPMNCPCHVQIFNQGLKSYRDLPLRLAEFGA-CHRNEPSGALHGIMRVRGF 378

Query: 345 TMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIR-----FTEDFWKEHK 399
           T  D H    + EQ K+E     KL+++V    G T    +++ R      +++ W   +
Sbjct: 379 TQDDAHIFCTE-EQVKKEAADFIKLTLQVYRDFGFTDIAMKLSTRPAKRVGSDELWDRAE 437

Query: 400 DFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGIT 459
             + + +   G  +  E       ++  K EF   D L +     T+Q D    ER   +
Sbjct: 438 GALADALNESG--LAWEYQPGEGAFYGPKIEFTLKDCLGRNWQCGTLQYDPNLPERLDAS 495

Query: 460 YYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVS 519
           Y  E+   K P++LH +  G+ ER +  ++E  A          FP WL+P Q  V+ ++
Sbjct: 496 YIAEDNNRKRPVMLHRAILGSFERFIGMLIEHYAGA--------FPAWLAPTQAVVMNIT 547

Query: 520 EEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITV 579
           ++  D+A  V   L  +  R   D  +E++  KIR      +PY++V+G RE E+  + V
Sbjct: 548 DKQADFAAEVVRILGESGFRAKSDLRNEKIGFKIREHTLLKVPYLLVIGDREVESKAVAV 607

Query: 580 RRRED---GKQYETRIEELIKE 598
           R RE    G    T+  EL+ +
Sbjct: 608 RTREGEDLGSMPVTQFAELLAQ 629


>pir||D82770 threonyl-tRNA synthetase XF0736 [imported] - Xylella fastidiosa
           (strain 9a5c) >gi|9105624|gb|AAF83546.1|AE003915_11
           (AE003915) threonyl-tRNA synthetase [Xylella fastidiosa]
           Length = 635
           
 Score =  135 bits (336), Expect = 2e-30
 Identities = 98/365 (26%), Positives = 165/365 (44%), Gaps = 15/365 (4%)

Query: 225 PGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIV 284
           PG + ++PKG +I   +E Y+       G  E+  P + D        + + +    +  
Sbjct: 262 PGLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSGHWDNYKENMFFT 321

Query: 285 LSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAF 344
            S  + Y ++   C G   +    + SYR+LP+R  E      R E  G L GL R+R F
Sbjct: 322 DSEKRTYAVKPMNCPGHVQVFNQGLHSYRDLPIRYGEFGA-CHRNEPSGALHGLLRVRGF 380

Query: 345 TMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIRFTEDFWKEHKDFIVE 404
           T  D H    +  Q + E     + +++V    G      ++A+R  +           E
Sbjct: 381 TQDDGHIFCTEA-QIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWDKAE 439

Query: 405 LVKLIGKPVLIEMWKQ---RFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYY 461
                        W++      ++  K E++  D + +   L T+Q+D     R G  Y 
Sbjct: 440 AALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGAEYV 499

Query: 462 DENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEE 521
           DE  +  +P++LH +  G++ER +  ++E  A +        +P WL+P+QV V  +++ 
Sbjct: 500 DERSQRCHPVMLHRAIVGSMERFIGILIEHYAGI--------WPTWLAPVQVVVANITDA 551

Query: 522 YLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVR- 580
             +YA  V   L     RV+ D  +E++  KIR    + +PY++VVG REKENGT+ VR 
Sbjct: 552 QYEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTVAVRT 611

Query: 581 -RRED 584
             RED
Sbjct: 612 CSRED 616


>pir||A81656 threonyl-tRNA synthetase TC0870 [imported] - Chlamydia muridarum
           (strain Nigg) >gi|7190897|gb|AAF39666.1| (AE002353)
           threonyl-tRNA synthetase [Chlamydia muridarum]
           Length = 635
           
 Score =  134 bits (334), Expect = 3e-30
 Identities = 101/381 (26%), Positives = 174/381 (45%), Gaps = 23/381 (6%)

Query: 230 YYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIVLSGDK 289
           ++P+G +I + L  Y        G  +++TP +   E   +  +   +    Y +   ++
Sbjct: 260 FHPRGMVIWNALIDYWKRLHQLAGYQQIQTPQLMSRELWEISGHWENYKENMYTLTVDEE 319

Query: 290 RYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDM 349
            Y ++   C G  +  K  + SYR  PLR+ E+  +  R E  G LSGL R+R F   D 
Sbjct: 320 DYAIKPMNCPGCMLYYKTQLHSYREFPLRIAEIG-HVHRHELSGALSGLMRVRTFHQDDA 378

Query: 350 HTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIRF--------TEDFWKEHKDF 401
           H      EQ +EE      L  E+    GL   DY + +          ++D W+   + 
Sbjct: 379 HVFLTP-EQVEEETLNILNLVSELYGTFGL---DYHLELSTRPEQGTIGSDDLWELATEA 434

Query: 402 IVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYY 461
           +   +    KP +I   +  F+    K + +  D +++     T+Q+D+   ERF + Y 
Sbjct: 435 LKNALVKSQKPFIISPGEGAFYG--PKIDIHVKDAINRTWQCGTIQLDMFLPERFDLKYT 492

Query: 462 DENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEE 521
           +  GE+  P++LH +  G+IER +  ++E          K  FPLWLSP  VR+I V++ 
Sbjct: 493 NPQGEKSTPIMLHRALFGSIERFLGILIEHF--------KGRFPLWLSPEHVRIITVADR 544

Query: 522 YLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRR 581
           +   A  +A       I   VD   E ++KKIR A+   + Y++ +G +E E   + VR 
Sbjct: 545 HEARAQELAKYFTQQGILATVDQASESVSKKIRNAQNMQVNYMITIGDKELETQLLAVRT 604

Query: 582 REDGKQYETRIEELIKEIKEK 602
           R++    +  +E     I E+
Sbjct: 605 RDNRVLNDISVEHFTNTILEE 625


>sp|P43014|SYT_HAEIN THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|1075350|pir||H64119 threonine--tRNA ligase (EC
           6.1.1.3) - Haemophilus influenzae
           >gi|1574199|gb|AAC23014.1| (U32816) threonyl-tRNA
           synthetase (thrS) [Haemophilus influenzae Rd]
           Length = 643
           
 Score =  133 bits (332), Expect = 5e-30
 Identities = 103/383 (26%), Positives = 169/383 (43%), Gaps = 17/383 (4%)

Query: 225 PGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIV 284
           PG + ++  G  I   LE +V  K+ +Y   EV+ P M D        +   +    +  
Sbjct: 261 PGMVFWHNDGWTIFRELETFVRTKLKQYDYQEVKGPFMMDRVLWEKTGHWQNYADLMFTT 320

Query: 285 LSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAF 344
            S ++ Y ++   C G   I    + SYR+LP+RM E      R E  G L GL R+R F
Sbjct: 321 QSENREYAIKPMNCPGHVQIFNQGLKSYRDLPIRMAEFGS-CHRNEPSGSLHGLMRVRGF 379

Query: 345 TMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIR-----FTEDFWKEHK 399
           T  D H    + +Q + E     K+  ++    G T    +++ R      +++ W   +
Sbjct: 380 TQDDAHIFCTE-DQIESEVTSCIKMVYDIYSTFGFTNIAVKLSTRPENRIGSDEMWDRAE 438

Query: 400 DFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGIT 459
             +   +   G    I+  +  F+    K EF   D L +     TVQ+D     R   T
Sbjct: 439 AGLAAALAHNGLEYEIQEGEGAFYG--PKIEFALRDCLGREWQCGTVQLDFALPGRLDAT 496

Query: 460 YYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVS 519
           Y  E+   K P+++H +  G+IER +  I E+ A          FP WL+P Q  V+ ++
Sbjct: 497 YVAEDNSRKTPVMIHRAILGSIERFIGIITEEYAGF--------FPAWLAPTQAVVMNIT 548

Query: 520 EEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITV 579
           +   DY   VA +L    +RV  D  +E++  KIR      +PY++V G +E   G + V
Sbjct: 549 DSQADYVQKVAKQLSDVGLRVKTDLRNEKVGFKIREHTLRRVPYMLVCGDKEIAEGKVAV 608

Query: 580 RRREDGKQYETRIEELIKEIKEK 602
           R R+        +EE  + +K +
Sbjct: 609 RTRKGADLGTFTVEEFAEILKNQ 631


>gi|4507367 threonyl-tRNA synthetase [Homo sapiens]
           >gi|135177|sp|P26639|SYTC_HUMAN THREONYL-TRNA
           SYNTHETASE, CYTOPLASMIC (THREONINE--TRNA LIGASE) (THRRS)
           >gi|319870|pir||YSHUT threonine--tRNA ligase (EC
           6.1.1.3) - human >gi|1464742|gb|AAB04939.1| (M63180)
           threonyl-tRNA synthetase [Homo sapiens]
           Length = 712
           
 Score =  133 bits (331), Expect = 6e-30
 Identities = 122/457 (26%), Positives = 202/457 (43%), Gaps = 39/457 (8%)

Query: 162 SYWYILTPEGELIEVDKFDFTGYENLRKFVNY-EIAKNRIAEKEPPHVKLMLEHELVDYE 220
           +YW        L  +    F   + L+++  + E AKNR   K     +L   HEL    
Sbjct: 271 TYWEGKADMETLQRIYGISFPDPKMLKEWEKFQEEAKNRDHRKIGRDQELYFFHEL---- 326

Query: 221 PGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPAR 280
               PG+  + PKG  I + L +++  +  + G  EV TP +++        +   +   
Sbjct: 327 ---SPGSCFFLPKGVYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSEN 383

Query: 281 QYIVLSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRR 340
            +      + + L+   C G  ++      S+R LPLR+ +      R E  G L+GL R
Sbjct: 384 MFSFEVEKELFALKPMNCPGHSLMFDHRPRSWRELPLRLADFGGLH-RNELSGALTGLTR 442

Query: 341 LRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLT--------PEDYEVAIRFTE 392
           +R F   D H     +EQ ++E K        V    G +        PE +   I   +
Sbjct: 443 VRRFQQDDAHIFCA-MEQIEDEIKGCLDFLRTVYSVFGFSFKLNLSTRPEKFLGDIEVWD 501

Query: 393 DFWKEHKDFIVELVKLIGKPVLIEMWKQRF---FYFILKFEFNFVDNLDKAAALSTVQID 449
              K+ ++ + E           E W+       ++  K +    D + +    +T+Q+D
Sbjct: 502 QAEKQLENSLNEFG---------EKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLD 552

Query: 450 VENAERFGITYYDENGEEKY-PLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWL 508
            +   RF +TY   +GE+K  P+I+H +  G++ER++  + E      N G K + P WL
Sbjct: 553 FQLPIRFNLTYVSHDGEDKKRPVIVHRAILGSVERMIAILTE------NYGGK-LAPFWL 605

Query: 509 SPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVD-DEDERLNKKIRRAEKEWIPYIVVV 567
           SP QV V+PV     +YA  V  +   AK   D+D D    LNKKIR A+     +I+VV
Sbjct: 606 SPRQVMVVPVGPTCDEYAQNVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILVV 665

Query: 568 GAREKENGTITVRRREDGKQYETRIEELIKEIKEKTE 604
           G +EK  GT+ +R R++    E  I E I+ +++  E
Sbjct: 666 GEKEKITGTVNIRTRDNKVHGERTISETIERLQQLKE 702


>sp|P87144|SYTC_SCHPO THREONYL-TRNA SYNTHETASE, CYTOPLASMIC (THREONINE--TRNA LIGASE)
           (THRRS) >gi|7493479|pir||T39997 Ths1p - fission yeast
           (Schizosaccharomyces pombe) >gi|2104451|emb|CAB08788.1|
           (Z95397) threonyl-trna synthetase, cytoplasmic
           [Schizosaccharomyces pombe]
           Length = 703
           
 Score =  129 bits (321), Expect = 9e-29
 Identities = 117/419 (27%), Positives = 188/419 (43%), Gaps = 35/419 (8%)

Query: 207 HVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFE 266
           H K+  + EL  +   S PG+  + P G  I + L +Y+  +  + G  EV TP MY+  
Sbjct: 291 HRKIGRDQELFFFNEIS-PGSCFFLPHGARIYNTLLKYMRYQYSKRGYQEVITPNMYNVN 349

Query: 267 HPALEKYLNRFPARQYIVLSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYS 326
                 + N +    +      ++Y L+   C G  ++ K    SYR+LP R+ +     
Sbjct: 350 LWKTSGHWNNYSENMFSFDIEKEKYALKPMNCPGHCVMFKSRDRSYRDLPWRVADFG-VL 408

Query: 327 FRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEV 386
            R E  G LSGL R+R F   D H      +Q + E +  F    EV    G T    E+
Sbjct: 409 HRNEFSGALSGLTRVRRFQQDDAHIFCTP-DQVRSEIEGCFDFLKEVYGTFGFTFH-LEL 466

Query: 387 AIRFTEDF------WKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKA 440
           + R  E +      W + +  +   +   G    +      F+    K +    D L + 
Sbjct: 467 STRPEEKYLGDLATWDKAEAQLKAALDASGYKWELNAGDGAFYG--PKIDITVFDALKRQ 524

Query: 441 AALSTVQIDVENAERFGITYY---------DENGEEKY--PLILHCSPSGAIERVMYAIL 489
              +T+Q+D +  ERF + ++         +     KY  P+++H +  G++ER++  + 
Sbjct: 525 HQCATIQLDFQLPERFQLEFHAPASAEEAKESGNNNKYTRPVMVHRAILGSLERMIAILT 584

Query: 490 EKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDEDERL 549
           E  A     GK   +P W+SP QV +IPVS    +YA  V   L  A I VD D  D  L
Sbjct: 585 EHYA-----GK---WPFWMSPRQVCIIPVSAAAYNYADKVHNILSEADIFVDTDKSDNTL 636

Query: 550 NKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYE----TRIEELIKEIKEKTE 604
            KKIR A+     +I VVGA E+   ++ VR R+D K+        +EE++K++ +  E
Sbjct: 637 PKKIRNAQLAQYNFIFVVGAEEESTNSVNVRNRDDPKKQSKGSTVAVEEVVKKLLKLKE 695


>emb|CAC11475.1| (AL445064) threonine--tRNA ligase related protein [Thermoplasma
           acidophilum]
           Length = 660
           
 Score =  129 bits (320), Expect = 1e-28
 Identities = 122/455 (26%), Positives = 198/455 (42%), Gaps = 61/455 (13%)

Query: 192 NYEIAKNRIAEKEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIE 251
           N E AK R       H +++ E +L  +     PG   Y   G+ I+  L  Y+     +
Sbjct: 217 NLEEAKRR------DHRRIIAEMDLAVFNSEWAPGFPLYTQYGQTIRKELLSYMDSMNRK 270

Query: 252 YGAMEVETPIMY-DFEHPALEKYLNRFPARQYIVLSGDKRYFLRFAACFGQFMIKKDAII 310
            G  +V TP ++ D        Y    P      L     Y ++   C G   I      
Sbjct: 271 NGWFDVWTPHVFRDTIWKQSGHYAKYRPNMYLFTLPDGDSYGIKPMNCPGHIAIFSRRKY 330

Query: 311 SYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLS 370
           SYR+LP+R Y      +R EK GE+ GL R RAFT  D H   + ++Q  +E +    + 
Sbjct: 331 SYRDLPVR-YSEPGTVYRYEKSGEVGGLTRPRAFTQDDGHAFLR-MDQIGDEIRTLLTMV 388

Query: 371 MEVLE----GVGLT----------PEDYEVAI------------RFTE------------ 392
            +V       + L+          PE+Y V+             R T+            
Sbjct: 389 KDVFTILFGNIELSFDLSVIDRDHPENYLVSYVCRNCGYRIEGARGTDIECPVCHSHDLE 448

Query: 393 ---DFWKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQID 449
                W    + + + +K +G  +  + +     ++  K + +  D + +   LST+Q+D
Sbjct: 449 PDLSVWDNATEQLRDALKSMG--IEYKEYPGEAAFYGPKIDVHVKDAIGRMWQLSTIQLD 506

Query: 450 VENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLS 509
                 FG+TY +  G+E   +++H +  G+ ERVM  +LE  A     GK    P WL+
Sbjct: 507 FFMPVNFGLTYTNSEGKEDRVVMIHRAIYGSYERVMAILLEHYA-----GK---LPTWLT 558

Query: 510 PIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGA 569
           PIQ  V+P+S  + +YA +V  +L    IR ++D   E ++KKI+        YI+VVG+
Sbjct: 559 PIQTYVVPISSNFDEYARHVHEELIRHGIRSEIDTSQETVSKKIKLIHPYRPAYIIVVGS 618

Query: 570 REKENGTITVRRREDGKQYETRIEELIKEIKEKTE 604
           +E E  ++T R RE GK     + E I  +K++ E
Sbjct: 619 KEMETNSVTARNRE-GKSKTYSLSEFIDVVKKEIE 652


>emb|CAC10316.1| (AL442629) SCH63.25, possible threonyl tRNA synthetase, len: 430
           aa; highly similar to C-terminal region of many threonyl
           tRNA synthetases, e.g. SW:SYT1_BACSU (EMBL:M36594)
           Bacillus subtilis threonyl tRNA synthetase 1 (EC
           6.1.1.3) ThrS, 643 aa; fasta s>
           Length = 430
           
 Score =  128 bits (318), Expect = 2e-28
 Identities = 109/416 (26%), Positives = 187/416 (44%), Gaps = 26/416 (6%)

Query: 199 RIAEKEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVE 258
           R  +++  H +L  E  L D +P    G   + P G +++  LE+YV E     G   V 
Sbjct: 21  RSHDRDHDHRRLGRELALFDTDPLMGAGLPYWLPDGAVVRHTLEEYVREAERRAGYRHVY 80

Query: 259 TPIMYDFEHPALEKYLNRFPARQYIVLS-GDKRYFLRFAACFGQFMIKKDAIISYRNLPL 317
           +P++   E   +  +   +    +  +  G +   LR + C    ++ +    SYR LPL
Sbjct: 81  SPVLGKRELYEISGHWEHYRDDMFPPMELGAEEVVLRPSLCPHHALVYRSRARSYRELPL 140

Query: 318 RMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGV 377
           R+ EL    +R E  G L GL R+RA  + D H      +QA  E +    L       +
Sbjct: 141 RIAELGAM-YRSEPSGVLGGLSRVRAIHLNDAHIFCTP-DQAAAEARAALGLIRRAHADL 198

Query: 378 GLTPEDYEVAI-----RFTED--FWKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFE 430
           G+    + +++     ++  D   W+     + E   L G P   E  +    ++  K +
Sbjct: 199 GIRAARHRLSLPGPGGKYVADPELWRRATALLEEA--LDGLPY--EAVEGEAAFYGPKID 254

Query: 431 FNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYAILE 490
               D   + + LSTVQID    ERFG+ Y   +G    P+++H S  G++ER +  ++E
Sbjct: 255 VQIEDAAGRESTLSTVQIDFHQPERFGLRYLGPDGARHRPVMVHRSVIGSVERAVAHLIE 314

Query: 491 KQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDV-DDEDERL 549
                        FP WL+P+Q+ V+PV+    + A  +  +     +R +V D E   L
Sbjct: 315 AHG--------GAFPAWLAPVQLVVLPVAGAQREAAYALVRQATDLGLRAEVADPERGSL 366

Query: 550 NKKIRRAEKEWIPYIVVVGAREKENG-TITVRRREDGKQYETRIEELIKEIKEKTE 604
             ++R A K  +PY  V+G RE ++G  + VR R+  +  +    EL+  I ++ E
Sbjct: 367 GARVRAARK--VPYQAVIGVREAQDGDLVDVRLRDGRRPGQLSGTELLHRITDRVE 420


>pir||E81439 threonine--tRNA ligase (EC 6.1.1.3) Cj0206 [imported] -
           Campylobacter jejuni (strain NCTC 11168)
           >gi|6967699|emb|CAB72689.1| (AL139074) threonyl-tRNA
           synthetase [Campylobacter jejuni]
           Length = 602
           
 Score =  126 bits (313), Expect = 8e-28
 Identities = 111/430 (25%), Positives = 191/430 (43%), Gaps = 29/430 (6%)

Query: 181 FTGYENLRKFVNY-EIAKNRIAEKEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKS 239
           F   E+L++++   E AK R       H KL  E +L  ++     G   +   G  ++S
Sbjct: 188 FADKESLKEYLTIIEEAKKR------DHRKLGTELKLFTFDDEIGGGLPIWLSNGARLRS 241

Query: 240 LLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIVLSGDKRYFLRFAACF 299
            LE  + +     G   V  P +   +   +  +   +    Y     ++ Y ++   C 
Sbjct: 242 KLEHMLYKIHRLRGYEPVRGPELLKADAWKISGHYANYKENMYFTQIDEQEYGIKPMNCV 301

Query: 300 GQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQA 359
           G   I +  + SYR+LPL+ +E      R EK G L GL R+R FT  D H       Q 
Sbjct: 302 GHIKIYQSDVRSYRDLPLKFFEYG-VVHRHEKSGVLHGLFRVREFTQDDAHIFCMP-SQI 359

Query: 360 KEEFKKQFKLSMEVLEGVGLTPEDYEVAIRFT-------EDFWKEHKDFIVELVKLIGKP 412
           KE+  +       +++   L    YE+ I          ++ W+     + E +   G  
Sbjct: 360 KEQVLEILAFVDNLMK---LFDFSYEMEISTKPEKAIGDDEIWEIATKALKEALDEQGLK 416

Query: 413 VLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLI 472
             I+     F+    K +    D L +     T+Q+D     RF + Y D + E+K P++
Sbjct: 417 YGIDEGGGAFYG--PKIDIKITDALKRKWQCGTIQVDFNLPSRFKLEYTDSDNEKKQPVM 474

Query: 473 LHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGK 532
           LH +  G+ ER +  + E  A          FP +++P  V ++P+ E ++ YA  +  +
Sbjct: 475 LHRAILGSFERFIGILTEHCAG--------EFPFFIAPTAVGIVPIGEAHIAYAKEIQKE 526

Query: 533 LEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYETRI 592
           L    I  +V +++E L+KKIR AEK+ +P I+V+G  E    ++ +R R   +Q    +
Sbjct: 527 LLELNIDSEVYEKNESLSKKIRIAEKQKLPMILVLGDDEVAKRSVALRDRRAKEQKNLSL 586

Query: 593 EELIKEIKEK 602
           +E IK +KEK
Sbjct: 587 DEFIKLVKEK 596


>gb|AAK40712.1| Threonyl-tRNA synthetase homolog (thrS-like) [Sulfolobus
           solfataricus]
           Length = 386
           
 Score =  118 bits (294), Expect = 1e-25
 Identities = 70/158 (44%), Positives = 96/158 (60%), Gaps = 14/158 (8%)

Query: 1   MRVLLIHSDYIEYEVKDKALKNPEPISEDMKRGRMEEVLVAFISVEKVDEKNPEEVSLKA 60
           M +L IH+    + VK++A+K PE     +K   ++  LV F +VEK D+   EE+  KA
Sbjct: 1   MIILFIHASDFSFNVKERAIKEPEEAK--LKSIELKNTLVCFTTVEKGDD---EEILSKA 55

Query: 61  IEEISKVAEQVKAENVFVYPFAHLSSELAKPSVAMDILNRVYQGLKERGFNVGKAPFGYY 120
           I++I  V  +VKA++V +YP+AHLSS LA P  A+ IL  +   LK++   V +APFG+Y
Sbjct: 56  IDDILDVYSKVKADSVVIYPYAHLSSNLANPDTAIKILESLENLLKDK-VKVYRAPFGWY 114

Query: 121 KAFKISCKGHPLAELSRTIVPEEARVEEVPEALRKEEE 158
           KAF ISC GHPL+ELSR I           E L K EE
Sbjct: 115 KAFSISCYGHPLSELSRRI--------RKTEELEKSEE 144


 Score =  108 bits (267), Expect = 2e-22
 Identities = 51/121 (42%), Positives = 81/121 (66%), Gaps = 5/121 (4%)

Query: 484 VMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVD 543
           + Y ILE   +     + P  P WL+PIQVR++PV +++LD+++ VA +L    IRV++D
Sbjct: 254 IYYFILESVKQ-----QPPTLPDWLNPIQVRLLPVKKDFLDFSIQVAERLRKEGIRVNID 308

Query: 544 DEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYETRIEELIKEIKEKT 603
           D D+ L  KIRRA  +WIP+++V+G RE +  T+TV+ R   +Q    +EEL+KEIK++ 
Sbjct: 309 DLDDSLGNKIRRAGTDWIPFVIVIGEREVKTNTLTVKIRARNEQKSMTVEELVKEIKDEV 368

Query: 604 E 604
           +
Sbjct: 369 K 369


>sp|P46244|SYT_BUCAP THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|2118340|pir||I40071 threonine--tRNA ligase (EC
           6.1.1.3) - Buchnera aphidicola >gi|868027|gb|AAC43605.1|
           (U11066) threonyl-tRNA synthetase [Buchnera aphidicola]
           >gi|1098080|prf||2115235B Thr-tRNA synthetase [Buchnera
           aphidicola]
           Length = 642
           
 Score =  116 bits (288), Expect = 7e-25
 Identities = 100/391 (25%), Positives = 179/391 (45%), Gaps = 32/391 (8%)

Query: 225 PGNLRYYPKGRLIKSLLEQYVTEK---VIEYGAMEVETPIMYDFEHPALEKYLNRFPARQ 281
           PG + ++  G +I + LE +V EK   +I Y   EV+TP++          + + +  R 
Sbjct: 260 PGMIFWHNNGWIIFNELEIFVREKLKGIINY--KEVKTPLLIHKSIWQKSGHWDNYQDRI 317

Query: 282 YIVLSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRL 341
           +   S ++ Y ++   C G   I    + SYR+LP+RM E      R E  G L GL R+
Sbjct: 318 FTTSSENREYCIKPMNCPGHVQIFNCGLKSYRDLPIRMAEFGS-CHRNESSGSLHGLMRI 376

Query: 342 RAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIRFT---------E 392
           R FT  D H      EQ + E     K+  ++           ++ ++F+         E
Sbjct: 377 RNFTQDDAHIFCTQ-EQLRYEINNCIKMIYDLYSTFNFK----KILVKFSTRPKKRIGDE 431

Query: 393 DFWKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVEN 452
             W + +  + ++  LI   +  E  +    ++  K EF   D+LD+     T+Q+D   
Sbjct: 432 SVWDQAEKDLSDV--LIENNLKFEHQEGEGAFYGPKIEFVLQDSLDRNWQCGTIQLDFYL 489

Query: 453 AERFGITYYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQ 512
             R    Y DE+  +K P+I+H +  G+IER +  ++E+  ++         P WLSPIQ
Sbjct: 490 PIRLRSFYIDEHNHQKIPIIIHRAILGSIERFIGILIEEFQEI---------PTWLSPIQ 540

Query: 513 VRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREK 572
           V ++ +++ +++Y   +        IRV+ D  +E++  KIR          + +  +EK
Sbjct: 541 VVILSITDSHINYVKKIVQHFSDINIRVESDLRNEKIGFKIRATYIASNSIYINLWRKEK 600

Query: 573 EN-GTITVRRREDGKQYETRIEELIKEIKEK 602
            N   I+VR R         I+  IK+++++
Sbjct: 601 LNLKKISVRTRNGYNLGIIDIDCFIKKLQKE 631


>emb|CAA21975.1| (AL033497) mitochondrial threonyl tRNA synthetase [Candida
           albicans]
           Length = 455
           
 Score =  116 bits (288), Expect = 7e-25
 Identities = 98/434 (22%), Positives = 190/434 (43%), Gaps = 43/434 (9%)

Query: 197 KNRIAEKEPPHVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAME 256
           K + AE       ++   +L+     + PG++ + P G  I + L Q++  +  +YG  E
Sbjct: 22  KTKEAESSTQSNHVISSKQLLYTTDPTSPGSIFFLPHGTRILNKLIQFMKNQQTKYGFQE 81

Query: 257 VETPIMY------------DFEHPALEKYLNRFPARQYIVLSGDKRYFLRFAACFGQFMI 304
           V TP+++            +++    +   N     +Y     +  Y L+   C    MI
Sbjct: 82  VVTPLIFKTKLWKKSGHWDNYKDDMFKVVGNDITKEEYTDNIEEHEYGLKPMNCPSHCMI 141

Query: 305 KKDAIISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFK 364
                 SY+ LP+R  + +    R E  G LSGL R+R F   D H     ++Q   E K
Sbjct: 142 FAKFDRSYQELPVRYSDFSSLH-RNEASGALSGLTRVRRFHQDDGHIFCS-MDQIDGEIK 199

Query: 365 KQFKLSMEVLEGVGLTPEDYEVAIRFTEDFWKEHKDFIV---ELVKLIGKPVLIEMWKQR 421
              +L  +     G+   ++ ++ R  + F  E + + +   +L  ++        W  R
Sbjct: 200 NTLELIKDTYNVFGINEIEFYLSTRPEDKFIGEIETWDIAESQLKNVLNSTAGEGNWATR 259

Query: 422 F---FYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKY-PLILHCSP 477
                ++  K +    D  +K   + T+Q+D +   RF + Y  E+G+  + P+++H + 
Sbjct: 260 EGDGAFYGPKIDVLLKDAFNKKHQVGTIQLDFQLPNRFELKYVGEDGKRDHQPILVHRAV 319

Query: 478 SGAIERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAK 537
            G++ER    +L+       +GK   +P W++P Q  ++P++E ++  A  +  KL G  
Sbjct: 320 FGSLERFFAILLDHY-----QGK---WPFWINPRQALIVPINESHVPVAEELQKKLSGDI 371

Query: 538 I--------------RVDVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRRE 583
           +               VD+D   E +  + + A ++   Y++++G ++  NGT  VR R+
Sbjct: 372 VSCDNAIAPLTGFTFHVDIDKRGETVGARTKDAIQKGYSYLIMIGDKDIANGTFAVRSRD 431

Query: 584 DGKQYETRIEELIK 597
           D K      +E+ K
Sbjct: 432 DRKIKNMTSDEIYK 445


>gb|AAF97275.1|AC034106_18 (AC034106) Strong similarity to threonyl-tRNA synthetase from
           Arabidopsis thaliana gb|Y14329 and is a member of the
           tRNA synthetase PF|00587 class II
           Length = 458
           
 Score =  116 bits (287), Expect = 9e-25
 Identities = 91/303 (30%), Positives = 141/303 (46%), Gaps = 26/303 (8%)

Query: 315 LPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVL 374
           LP+RM E      R E  G L G+ R+R F   D H   + ++Q +EE K        V 
Sbjct: 170 LPIRMAEFG-VLHRNEDSGALGGMTRVRRFVQDDAHIFCR-VDQVEEEVKGVLDFIDYVY 227

Query: 375 EGVGLTPEDYEVAIRFTE-------DFWKEHKDFIVELVKLIGKPVLIEMWKQRFFYFIL 427
              G T   YE+ +           + W + ++ + + +   GKP +I+     F+    
Sbjct: 228 RIFGFT---YELTLSTRPKDHIGDLETWAKAENDLEKALDDFGKPWVIKEGDGAFYG--P 282

Query: 428 KFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYA 487
           K +    D  ++    +T+Q+D +    F + Y  E  E + P+++H +  G+IER+   
Sbjct: 283 KIDITVSDARNRKFQCATIQLDFQLPACFKLKYLSEKNEMEAPVMIHSAVLGSIERMFAI 342

Query: 488 ILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDEDE 547
           +LE          K ++P WLSP Q  V  +SE+   YA  V  ++      VD+D+ D 
Sbjct: 343 LLEHY--------KGIWPFWLSPRQAIVCSLSEDCSSYAKQVQKQINEVGYYVDIDESDR 394

Query: 548 RLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRRED--GKQ--YETRIEELIKEIKEKT 603
            L KK+  A      YI+VVG +E   G +TVR RED  G++   E  IE L+ E K KT
Sbjct: 395 SLRKKVADARDAPYNYILVVGQKEVATGQVTVRLREDPEGRKDLPEMSIESLLDEFKFKT 454

Query: 604 EGF 606
             F
Sbjct: 455 VNF 457


>gi|6322654 mitochondrial threonine-tRNA synthetase; Mst1p [Saccharomyces
           cerevisiae] >gi|549032|sp|P07236|SYTM_YEAST
           THREONYL-TRNA SYNTHETASE, MITOCHONDRIAL PRECURSOR
           (THREONINE--TRNA LIGASE) (THRRS) >gi|538561|pir||YSBYTM
           threonine--tRNA ligase (EC 6.1.1.3) precursor,
           mitochondrial - yeast (Saccharomyces cerevisiae)
           >gi|486345|emb|CAA82038.1| (Z28194) ORF YKL194c
           [Saccharomyces cerevisiae]
           Length = 462
           
 Score =  113 bits (279), Expect = 8e-24
 Identities = 104/402 (25%), Positives = 176/402 (42%), Gaps = 51/402 (12%)

Query: 225 PGNLRYYPKG-RLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYI 283
           PG++ + P G ++   L+E    ++  ++G  EV TP++Y         +   +    + 
Sbjct: 56  PGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFK 115

Query: 284 VLSGDKR---YFLRFAACFGQFMI--KKDAIISYRNLPLRMYELTRYSFRREKRGELSGL 338
           V + D+    Y L+   C G  +I  KKD   SY  LPLR  + +    R E  G LSGL
Sbjct: 116 VETTDEEKEEYGLKPMNCPGHCLIFGKKDR--SYNELPLRFSDFSPLH-RNEASGALSGL 172

Query: 339 RRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEV-------LEGVGLTPEDYEVAIRFT 391
            RLR F   D H       Q K E     KL   V       ++G      +Y +     
Sbjct: 173 TRLRKFHQDDGHIFCTP-SQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAESNYFINFSTR 231

Query: 392 EDF-------WKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALS 444
            D        W   +  + E+++  GKP  +      F+    K +    D+L K   ++
Sbjct: 232 PDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYG--PKLDIMVTDHLRKTHQVA 289

Query: 445 TVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMF 504
           T+Q+D +  ERF + + D++   K P+++H +  G+IER M  +++      NEG+   +
Sbjct: 290 TIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDS-----NEGR---W 341

Query: 505 PLWLSPIQVRVIPVSE---EYLDYALYVAGKLEGA--------------KIRVDVDDEDE 547
           P WL+P Q  +IPV+    + LD    +  KL                    VD+D  +E
Sbjct: 342 PFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNE 401

Query: 548 RLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYE 589
            +  +I+ A  +   Y+++VG  E +     +R R++ K +E
Sbjct: 402 PVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFE 443


>gb|AAA34808.1| (M12087) thr-tRNA-synthetase [Saccharomyces cerevisiae]
           Length = 462
           
 Score =  112 bits (278), Expect = 1e-23
 Identities = 104/402 (25%), Positives = 176/402 (42%), Gaps = 51/402 (12%)

Query: 225 PGNLRYYPKG-RLIKSLLEQYVTEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYI 283
           PG++ + P G ++   L+E    ++  ++G  EV TP++Y         +   +    + 
Sbjct: 56  PGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFK 115

Query: 284 VLSGDKR---YFLRFAACFGQFMI--KKDAIISYRNLPLRMYELTRYSFRREKRGELSGL 338
           V + D+    Y L+   C G  +I  KKD   SY  LPLR  + +    R E  G LSGL
Sbjct: 116 VETTDEEKEEYGLKPMNCPGHCLIFGKKDR--SYNELPLRFSDFSPLH-RNEASGALSGL 172

Query: 339 RRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEV-------LEGVGLTPEDYEVAIRFT 391
            RLR F   D H       Q K E     KL   V       ++G      +Y +     
Sbjct: 173 TRLRKFHQDDGHIFCTP-SQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAESNYFINFSTR 231

Query: 392 EDF-------WKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALS 444
            D        W   +  + E+++  GKP  +      F+    K +    D+L K   ++
Sbjct: 232 PDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPSDGAFYG--PKLDIMVTDHLRKTHQVA 289

Query: 445 TVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMF 504
           T+Q+D +  ERF + + D++   K P+++H +  G+IER M  +++      NEG+   +
Sbjct: 290 TIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDS-----NEGR---W 341

Query: 505 PLWLSPIQVRVIPVSE---EYLDYALYVAGKLEGA--------------KIRVDVDDEDE 547
           P WL+P Q  +IPV+    + LD    +  KL                    VD+D  +E
Sbjct: 342 PFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNE 401

Query: 548 RLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYE 589
            +  +I+ A  +   Y+++VG  E +     +R R++ K +E
Sbjct: 402 PVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFE 443


>emb|CAA26666.1| (X02906) threonyl-tRNA synthetase (aa 1-734) [Saccharomyces
           cerevisiae]
           Length = 734
           
 Score =  111 bits (274), Expect = 3e-23
 Identities = 107/406 (26%), Positives = 180/406 (43%), Gaps = 26/406 (6%)

Query: 207 HVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFE 266
           H K+  E EL  +   S PG+  + P G  I + L   +  +  + G  EV TP MY+ +
Sbjct: 330 HRKIGKEQELFLFNEMS-PGSCFWLPHGTRIYNTLVDLLRTEYRKRGYEEVITPNMYNSK 388

Query: 267 HPALEKYLNRFPARQYIVLSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYS 326
                 +   +    +      + + L+   C G  ++ K    SYR LP R+ +     
Sbjct: 389 LWETSGHWANYKENMFTFEVEKETFGLKPMNCPGHCLMFKSRERSYRELPWRVADFG-VI 447

Query: 327 FRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEV 386
            R E  G LSGL R+R F   D H      +Q + E +  F   ++ + GV     + E+
Sbjct: 448 HRNEFSGALSGLTRVRRFQQDDAHIFCTH-DQIESEIENIFNF-LQYIYGVFGFEFEMEL 505

Query: 387 AIRFTE-----DFWKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAA 441
           + R  +     + W   +  +   +K  G    I      F+    K +    D L +  
Sbjct: 506 STRPEKYVGKIETWDAAESKLESALKKWGGNWEINAGDGAFYG--PKIDIMISDALRRWH 563

Query: 442 ALSTVQIDVENAERFGITYYDENGE-EKY--PLILHCSPSGAIERVMYAILEKQAKLMNE 498
             +T+Q+D +   RF + +  ++ + E Y  P+++H +  G++ER+   + E  A     
Sbjct: 564 QCATIQLDFQLPNRFELEFKSKDQDSESYERPVMIHRAILGSVERMTAILTEHFA----- 618

Query: 499 GKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEK 558
           GK   +P WLSP QV V+PV  +Y  YA  V  KL  A    DVD     L KK+R  + 
Sbjct: 619 GK---WPFWLSPRQVLVVPVGVKYQGYAEDVRNKLHDAGFYADVDLTGNTLQKKVRNGQM 675

Query: 559 EWIPYIVVVGAREKENGTITVRRR----EDGKQYETRIEELIKEIK 600
               +I +VG +E    ++ +R R    + GK     +EE++K+++
Sbjct: 676 LKYNFIFIVGEQEMNEKSVNIRNRDVMEQQGKNATVSVEEVLKQLR 721


>gi|6322112 Threonyl-tRNA synthetase, cytoplasmic; Ths1p [Saccharomyces
           cerevisiae] >gi|730881|sp|P04801|SYTC_YEAST
           THREONYL-TRNA SYNTHETASE, CYTOPLASMIC (THREONINE--TRNA
           LIGASE) (THRRS) >gi|625247|pir||YSBYTC threonine--tRNA
           ligase (EC 6.1.1.3), cytosolic - yeast  (Saccharomyces
           cerevisiae) >gi|556869|emb|CAA86092.1| (Z37997)
           threonyl-tRNA synthetase [Saccharomyces cerevisiae]
           Length = 734
           
 Score =  111 bits (274), Expect = 3e-23
 Identities = 109/410 (26%), Positives = 178/410 (42%), Gaps = 34/410 (8%)

Query: 207 HVKLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFE 266
           H K+  E EL  +   S PG+  + P G  I + L   +  +  + G  EV TP MY+ +
Sbjct: 330 HRKIGKEQELFLFNEMS-PGSCFWLPHGTRIYNTLVDLLRTEYRKRGYEEVITPNMYNSK 388

Query: 267 HPALEKYLNRFPARQYIVLSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYS 326
                 +   +    +      + + L+   C G  ++ K    SYR LP R+ +     
Sbjct: 389 LWETSGHWANYKENMFTFEVEKETFGLKPMNCPGHCLMFKSRERSYRELPWRVADFG-VI 447

Query: 327 FRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGV--------- 377
            R E  G LSGL R+R F   D H      +Q + E +  F   ++ + GV         
Sbjct: 448 HRNEFSGALSGLTRVRRFQQDDAHIFCTH-DQIESEIENIFNF-LQYIYGVFGFEFKMEL 505

Query: 378 GLTPEDYEVAIRFTEDFWKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNL 437
              PE Y   I    + W   +  +   +K  G    I      F+    K +    D L
Sbjct: 506 STRPEKYVGKI----ETWDAAESKLESALKKWGGNWEINAGDGAFYG--PKIDIMISDAL 559

Query: 438 DKAAALSTVQIDVENAERFGITYYDENGE-EKY--PLILHCSPSGAIERVMYAILEKQAK 494
            +    +T+Q+D +   RF + +  ++ + E Y  P+++H +  G++ER+   + E  A 
Sbjct: 560 RRWHQCATIQLDFQLPNRFELEFKSKDQDSESYERPVMIHRAILGSVERMTAILTEHFA- 618

Query: 495 LMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKIR 554
               GK   +P WLSP QV V+PV  +Y  YA  V  KL  A    DVD     L KK+R
Sbjct: 619 ----GK---WPFWLSPRQVLVVPVGVKYQGYAEDVRNKLHDAGFYADVDLTGNTLQKKVR 671

Query: 555 RAEKEWIPYIVVVGAREKENGTITVRRR----EDGKQYETRIEELIKEIK 600
             +     +I +VG +E    ++ +R R    + GK     +EE++K+++
Sbjct: 672 NGQMLKYNFIFIVGEQEMNEKSVNIRNRDVMEQQGKNATVSVEEVLKQLR 721


>dbj|BAB14117.1| (AK022590) unnamed protein product [Homo sapiens]
           Length = 588
           
 Score =  102 bits (253), Expect = 9e-21
 Identities = 83/299 (27%), Positives = 140/299 (46%), Gaps = 23/299 (7%)

Query: 311 SYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLS 370
           S+R LPLR+ +      R E  G L GL RLR F   D H      +Q + E +      
Sbjct: 292 SWRELPLRLADFGALH-RAEASGGLGGLTRLRCFQQDDAHIFCTT-DQLEAEIQSCLDFL 349

Query: 371 MEVLEGVGLTPEDYEVAIR-----FTED--FWKEHKDFIVELVKLIGKPVLIEMWKQRFF 423
             V   +G +   + +A+      F  D   W + +  + + +K  G+P  +      F+
Sbjct: 350 RSVYAVLGFS---FRLALSTRPSGFLGDPCLWDQAEQVLKQALKEFGEPWDLNSGDGAFY 406

Query: 424 YFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIER 483
               K + +  D L +     T+Q+D +   RF + Y  + G  + P+++H +  G++ER
Sbjct: 407 G--PKIDVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKGQAGALERPVLIHRAVLGSVER 464

Query: 484 VMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVD 543
           ++  + E        GK   +PLWLSP QV VIPV  E  +YA      L  A +  D+D
Sbjct: 465 LLGVLAESCG-----GK---WPLWLSPFQVVVIPVGSEQEEYAKEAQQSLRAAGLVSDLD 516

Query: 544 -DEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYETRIEELIKEIKE 601
            D    L+++IRRA+     +  VVG +E+   T+ +R R++ +  E  + E ++ + E
Sbjct: 517 ADSGLTLSRRIRRAQLAHYNFQFVVGQKEQSKRTVNIRTRDNRRLGEWDLPEAVQRLVE 575


>sp|O13969|SYTM_SCHPO PROBABLE THREONYL-TRNA SYNTHETASE, MITOCHONDRIAL PRECURSOR
           (THREONINE--TRNA LIGASE) (THRRS) >gi|7493478|pir||T38350
           threonine-tRNA ligase precursor, mitochondrial - fission
           yeast (Schizosaccharomyces pombe)
           >gi|2330792|emb|CAB11266.1| (Z98601) mitochondrial
           threonyl trna synthetase [Schizosaccharomyces pombe]
           Length = 473
           
 Score = 98.7 bits (242), Expect = 2e-19
 Identities = 100/420 (23%), Positives = 178/420 (41%), Gaps = 50/420 (11%)

Query: 225 PGNLRYYPKGRLIKSLLEQYVTEKVIEYGAMEVETPIMYDFE-------HPALEKYLNRF 277
           PG++ + P G  I + L  ++  +   +G  E+ TP+++  +           EK + R 
Sbjct: 65  PGSIFFLPHGTRIYNRLVDFLRAQYQIHGFEEIITPLIFKKDLWEKSGHWQNYEKEIFRV 124

Query: 278 P-ARQYIVLSGDKRYFLRFAACFGQFMIKKDAIISYRNLPLRMYELTRYSFRREKRGELS 336
             +R       +  Y L+   C G  ++      SY+ LPLR  + +    R E  G LS
Sbjct: 125 EESRNVEDEHSNATYGLKPMNCPGHCIVYASTERSYKELPLRFADFSPLH-RNEASGALS 183

Query: 337 GLRRLRAFTMPDMHTLAKDIEQAKEEFKKQFKLSMEVLEGVGLTPEDYEVAIRFTE---- 392
           GL RLR F   D H      E  K+E K       +V   +G+      ++ R  E    
Sbjct: 184 GLTRLRCFHQDDGHIFCSP-ESIKDEIKNTLTFVKQVYSLLGMNKLKLYLSTRPEEHIGS 242

Query: 393 -DFWKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVE 451
            D W E ++ + E ++  G+  +I      F+    K +    D   K    +T+Q+D  
Sbjct: 243 LDTWNEAENGLREALQESGETWIINEGDGAFYG--PKIDVMVADARGKWHQTATIQLDFN 300

Query: 452 NAERFGITYYDENGEE-------KYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMF 504
             +RF + Y  + G+        K P+++H +  G++ER M  ++E             +
Sbjct: 301 LPQRFKLYYRTDAGDNAGSEKLIKQPVMIHRAIFGSLERFMGILIEHL--------NGHW 352

Query: 505 PLWLSPIQVRVIPV--SEEYLDYALYVAGKLEGAKIR-------------VDVDDEDERL 549
           P WLSP    ++PV  ++  L YA  V  +L   ++              VD++ E + +
Sbjct: 353 PFWLSPRHAVILPVNQTDRILTYAKQVQKELSNQEVNESEFLPLNKNTYYVDINAEAQSI 412

Query: 550 NKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYETR---IEELIKEIKEKTEGF 606
            K++R +      Y +V+G  E +   ++V  R +    +TR   I++L KE  E  + +
Sbjct: 413 GKRLRESRLLNYNYEIVIGEDEVDKEILSVSSRHNHNSRDTRKMTIQQLKKEFIENVKAY 472


>sp|Q9YFY3|SYT2_AERPE PROBABLE THREONYL-TRNA SYNTHETASE 2 (THREONINE--TRNA LIGASE 2)
           (THRRS 2) >gi|7521473|pir||B72766 probable threonyl-tRNA
           synthetase APE0117 - Aeropyrum pernix (strain K1)
           >gi|5103507|dbj|BAA79028.1| (AP000058) 406aa long
           hypothetical threonyl-tRNA synthetase [Aeropyrum pernix]
           Length = 406
           
 Score = 85.0 bits (207), Expect = 2e-15
 Identities = 53/121 (43%), Positives = 73/121 (59%), Gaps = 7/121 (5%)

Query: 19  ALKNPEPISEDMKRGRMEEVLVAFISVEKVDEKNPEEVSLKAIEEISKVAEQVKAENVFV 78
           ALKNP     +   G   E LV F +VE  D   P+ V + A  +I+  + ++K   V +
Sbjct: 4   ALKNPPDPPGEASFG---EALVVFTTVE--DGDGPQTV-MYAASDIASHSSRLKVTTVIL 57

Query: 79  YPFAHLSSELAKPSVAMDILNRVYQGLKER-GFNVGKAPFGYYKAFKISCKGHPLAELSR 137
           YP+AHLSS LAKP  A   L  +   L+ +   +V +APFG+YK+F I+CKGHPLAELSR
Sbjct: 58  YPYAHLSSRLAKPMAAHKRLIELEGALRTKFPGHVHRAPFGWYKSFSIACKGHPLAELSR 117

Query: 138 T 138
           +
Sbjct: 118 S 118


 Score = 73.7 bits (178), Expect = 6e-12
 Identities = 43/113 (38%), Positives = 60/113 (53%), Gaps = 2/113 (1%)

Query: 494 KLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKI 553
           K   EG  P     L+P+Q  VIPV  E   YA  +A  L  + +RV +      L +++
Sbjct: 285 KARKEGLTPYLNPTLTPVQSAVIPVDSESEGYAQRIAEDLAASGVRVSIV-RGSGLGRRV 343

Query: 554 RRAEKEWIPYIVVVGAREKENGTITVRRR-EDGKQYETRIEELIKEIKEKTEG 605
           R A + W   ++VVG RE+E GT+ VRRR E GKQ    ++EL  E K+   G
Sbjct: 344 REAGRSWASLVIVVGKREEETGTVVVRRRWEPGKQEVLTLDELSSEAKKLASG 396


>sp|P52833|SYT_PSESY THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
           >gi|1171431|gb|AAB05013.1| (U44118) threonyl-tRNA
           synthetase [Pseudomonas syringae pv. syringae]
           Length = 227
           
 Score = 84.7 bits (206), Expect = 3e-15
 Identities = 54/193 (27%), Positives = 94/193 (47%), Gaps = 10/193 (5%)

Query: 391 TEDFWKEHKDFIVELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDV 450
           +++ W   +  +   +   G+P  ++  +  F+    K EF+  D L +     T+Q+D 
Sbjct: 16  SDELWDRAESALASALDSAGQPYDLQPGEGAFYG--PKIEFSLKDCLGRVWQCGTLQLDF 73

Query: 451 ENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMFPLWLSP 510
               R    Y  E+   K P++LH +  G+ ER +  ++E       EG    FP WL+P
Sbjct: 74  NLPIRLSAEYVSEDNSRKNPVMLHRAILGSFERFIGILIEHY-----EGA---FPAWLAP 125

Query: 511 IQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYIVVVGAR 570
            Q  ++ ++++  D+AL V   L  +  R   D  +E++  KIR      +PY++V+G R
Sbjct: 126 TQAVIMNITDKQADFALEVEKTLAESGFRAKSDLRNEKIGFKIREHTLLKVPYLLVIGDR 185

Query: 571 EKENGTITVRRRE 583
           E E  T+ VR RE
Sbjct: 186 EVEMQTVAVRTRE 198


>gb|AAD34790.1|AF136400_4 (AF136400) threonyl-tRNA synthetase [Pseudomonas fluorescens]
           Length = 161
           
 Score = 79.6 bits (193), Expect = 1e-13
 Identities = 47/139 (33%), Positives = 74/139 (52%), Gaps = 8/139 (5%)

Query: 445 TVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMNEGKKPMF 504
           T+Q+D     R G  Y  E+   K+P++LH +  G+ ER +  ++E       EG    F
Sbjct: 2   TLQLDFNLPIRLGAEYVSEDNSRKHPVMLHRAILGSFERFVGILIEHY-----EGA---F 53

Query: 505 PLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRVDVDDEDERLNKKIRRAEKEWIPYI 564
           P WL+P Q  V+ ++++  D+AL V   L  +  R   D  +E++  KIR      +PY+
Sbjct: 54  PAWLAPTQAVVMNITDKQADFALEVEKTLNQSGFRAKSDLRNEKIGFKIREHTLLKVPYL 113

Query: 565 VVVGAREKENGTITVRRRE 583
           +V+G RE E  T+ VR RE
Sbjct: 114 LVIGDREVEMQTVAVRTRE 132


>gb|AAF78372.1|AC069551_5 (AC069551) T10O22.10 [Arabidopsis thaliana]
           Length = 270
           
 Score = 79.6 bits (193), Expect = 1e-13
 Identities = 63/186 (33%), Positives = 90/186 (47%), Gaps = 22/186 (11%)

Query: 422 FFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEE-KYPLILHCSPSGA 480
           FF+F   F          A  L+   +D    +RF + Y  EN    +  +++H +   +
Sbjct: 105 FFFFFFLFP---------AFLLAVYLVDFHLRDRFKLEYSAENETMIERSVLIHRAVLSS 155

Query: 481 IERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRV 540
           +ER ++AIL +Q K    GK   FP WLSP Q  V  VSE+Y  YA  V  ++  A   V
Sbjct: 156 VER-LFAILLEQYK----GK---FPFWLSPRQAIVCSVSEDYRSYADKVRDQIHEAGYYV 207

Query: 541 DVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYETRIEELIKEIK 600
           DVD  D  ++ K++ A+     YI+VVG  E   G +TV  R++    ET    L  E K
Sbjct: 208 DVDTTDRNVSDKVQEAQVAHYNYILVVGDEEARTGQVTVWLRDEMMSIET----LSDEFK 263

Query: 601 EKTEGF 606
            KT  F
Sbjct: 264 LKTANF 269


>gb|AAF97829.1|AC034107_12 (AC034107) Contains similarity to threonyl-tRNA synthetase from
           Arabidopsis thaliana gb|Y14329
           Length = 130
           
 Score = 73.0 bits (176), Expect = 9e-12
 Identities = 46/126 (36%), Positives = 64/126 (50%), Gaps = 4/126 (3%)

Query: 481 IERVMYAILEKQAKLMNEGKKPMFPLWLSPIQVRVIPVSEEYLDYALYVAGKLEGAKIRV 540
           I R + + +E+   ++ E  K  FP WLSP Q  V  VSE+Y  YA  V  ++  A   V
Sbjct: 8   IHRAVLSSVERLFAILLEQYKGKFPFWLSPRQAIVCSVSEDYRSYADKVRDQIHEAGYYV 67

Query: 541 DVDDEDERLNKKIRRAEKEWIPYIVVVGAREKENGTITVRRREDGKQYETRIEELIKEIK 600
           DVD  D  ++ K++ A+     YI+VVG  E   G +TV  R++    ET    L  E K
Sbjct: 68  DVDTTDRNVSDKVQEAQVAHYNYILVVGDEEARTGQVTVWLRDEMMSIET----LSDEFK 123

Query: 601 EKTEGF 606
            KT  F
Sbjct: 124 LKTANF 129


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.319    0.139    0.399 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 239413458
Number of Sequences: 2977
Number of extensions: 10614569
Number of successful extensions: 33130
Number of sequences better than 1.0e-10: 67
Number of HSP's better than  0.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 32843
Number of HSP's gapped (non-prelim): 80
length of query: 625
length of database: 189,106,746
effective HSP length: 58
effective length of query: 567
effective length of database: 154,394,500
effective search space: 87541681500
effective search space used: 87541681500
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 168 (69.9 bits)