BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1502 (argF) DE:ornithine carbamoyltransferase (argF)
(317 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
sp|O93656|OTC_PYRAB ORNITHINE CARBAMOYLTRANSFERASE (OTCASE) >gi|... 647 0.0
sp|O58457|OTC_PYRHO ORNITHINE CARBAMOYLTRANSFERASE (OTCASE) >gi|... 636 0.0
gb|AAD09004.1| (AF083209) ornithine carbamoyltransferase [Pyroco... 631 e-180
pdb|1A1S| Ornithine Carbamoyltransferase From Pyrococcus Furiosus 626 e-179
sp|Q51742|OTC_PYRFU ORNITHINE CARBAMOYLTRANSFERASE (OTCASE) >gi|... 624 e-178
pir||T45077 ornithine carbamoyltransferase [imported] - Pyrococc... 621 e-177
dbj|BAB06613.1| (AP001517) ornithine carbamoyltransferase [Bacil... 372 e-102
sp|P18186|OTCA_BACSU ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (O... 367 e-100
gb|AAC78720.1| (U43091) ornithine carbamoyltransferase [Bacillus... 363 2e-99
pir||B72502 probable ornithine carbamoyltransferase APE1992 - Ae... 351 6e-96
gi|11498854 ornithine carbamoyltransferase (argF) [Archaeoglobus... 340 1e-92
sp|O27495|OTC_METTH ORNITHINE CARBAMOYLTRANSFERASE (OTCASE) >gi|... 331 6e-90
sp|Q58291|OTC_METJA ORNITHINE CARBAMOYLTRANSFERASE (OTCASE) >gi|... 323 2e-87
emb|CAC12451.1| (AL445067) probable ornithine carbamoyltransfera... 322 4e-87
gb|AAF17705.1|AF033562_1 (AF033562) ornithine carbamoyltransfera... 306 3e-82
sp|Q43814|OTC_PEA ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OTCA... 305 3e-82
sp|Q55497|OTCA_SYNY3 ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (O... 305 4e-82
dbj|BAA22924.1| (D86376) ArgF [Bacillus subtilis] 301 6e-81
gb|AAG13075.1|AC023754_13 (AC023754) Ornithine carbamoyltransfer... 301 8e-81
gb|AAC36050.1| (AF030524) ornithine carbamoyltransferase; OCT [N... 299 3e-80
gb|AAF17704.1|AF033561_1 (AF033561) ornithine carbamoyltransfera... 296 3e-79
pir||E70447 ornithine carbamoyltransferase - Aquifex aeolicus >g... 294 1e-78
sp|O50039|OTC_ARATH ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OT... 293 1e-78
pir||E83203 ornithine carbamoyltransferase, anabolic PA3537 [imp... 292 4e-78
sp|O86132|OTCC_BACLI ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC (... 291 6e-78
sp|P11724|OTCA_PSEAE ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (O... 289 4e-77
gi|6679184 ornithine transcarbamylase [Mus musculus] >gi|129277|... 287 8e-77
sp|Q02095|OTCA_MYCBO ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (O... 286 2e-76
sp|O19072|OTC_PIG ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OTCA... 286 3e-76
gb|AAF61405.1|AF134841_1 (AF134841) ornithine transcarbamylase [... 286 3e-76
sp|P94991|OTCA_MYCTU ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (O... 285 4e-76
gi|6981312 ornithine carbamoyltransferase [Rattus norvegicus] >g... 285 4e-76
sp|P96108|OTCA_THEMA ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (O... 285 4e-76
emb|CAA30121.1| (X07092) ornithine transcarbamylase [Mus musculus] 284 7e-76
sp|P00480|OTC_HUMAN ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OT... 284 9e-76
prf||1403355A Orn transcarbamylase [Homo sapiens] 284 9e-76
emb|CAA26007.1| (X01976) OTCase precursor [Rattus norvegicus] 283 2e-75
pir||JE0309 ornithine carbamoyltransferase (EC 2.1.3.3) - chicke... 282 3e-75
pdb|1C9Y|A Chain A, Human Ornithine Transcarbamylase: Crystallog... 282 5e-75
gb|AAF61410.1|AF134846_1 (AF134846) ornithine transcarbamylase [... 281 6e-75
sp|Q48296|OTC_HALSA ORNITHINE CARBAMOYLTRANSFERASE (OTCASE) >gi|... 280 1e-74
sp|Q02047|OTCA_PSESH ORNITHINE CARBAMOYLTRANSFERASE, PHASEOLOTOX... 280 1e-74
gb|AAA41772.1| (K00001) preornithine carbamoyl transferase [Ratt... 280 2e-74
gb|AAF61409.1|AF134845_1 (AF134845) ornithine transcarbamylase [... 279 4e-74
sp|P96134|OTCA_THETH ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (O... 278 5e-74
gi|9257234 ornithine carbamoyltransferase precursor; Ornithine t... 276 3e-73
pir||F75562 ornithine carbamoyltransferase - Deinococcus radiodu... 276 3e-73
gb|AAF61406.1|AF134842_1 (AF134842) ornithine transcarbamylase [... 275 6e-73
sp|P31326|OTC_RANCA ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OT... 274 8e-73
gb|AAK41159.1| Ornithine carbamoyltransferase (argF) [Sulfolobus... 272 4e-72
gb|AAF61407.1|AF134843_1 (AF134843) ornithine transcarbamylase [... 271 9e-72
gb|AAF61408.1|AF134844_1 (AF134844) ornithine transcarbamylase [... 266 3e-70
sp|P96172|OTCA_VIBS2 ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (O... 257 9e-68
emb|CAB95022.1| (AJ252021) ornithine carbamoyltransferase [Morit... 255 4e-67
sp|P31317|OTC_SCHPO ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OT... 254 1e-66
emb|CAB95016.1| (AJ252020) ornithine carbamoyltransferase [Morit... 252 3e-66
sp|Q59283|OTCA_CORGL ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (O... 252 5e-66
pir||T46742 ornithine carbamoyltransferase (EC 2.1.3.3) [validat... 248 8e-65
gb|AAB93999.1| (AF008219) ArcB [Borrelia afzelii] 247 2e-64
pir||G81374 ornithine carbamoyltransferase (EC 2.1.3.3) Cj0994c ... 246 2e-64
pir||A70205 ornithine carbamoyltransferase, catabolic (arcB) hom... 244 1e-63
emb|CAB93580.1| (AJ250129) ornithine transcarbamylase [Lactococc... 243 1e-63
gb|AAF86986.1|AF282249_5 (AF282249) ArcB [Lactococcus lactis sub... 242 4e-63
sp|O08322|OTCA_LACPL ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (O... 239 4e-62
sp|O31018|OTCC_RHIET ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC (... 238 8e-62
sp|P11066|OTC_ASPNG ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OT... 237 1e-61
sp|P11803|OTC_EMENI ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OT... 237 1e-61
pir||OWASN ornithine carbamoyltransferase (EC 2.1.3.3) precursor... 237 1e-61
dbj|BAA35119.1| (AB020737) ornithine carbamoyltransferase [Asper... 237 1e-61
pir||B81801 ornithine carbamoyltransferase (EC 2.1.3.3) NMA1762 ... 236 2e-61
gb|AAD32177.1|AF125563_2 (AF125563) ornithine carbomyltransferas... 235 4e-61
pir||F82066 ornithine carbamoyltransferase VC2508 [imported] - V... 235 4e-61
pir||E81066 ornithine carbamoyltransferase, catabolic NMB1573 [i... 235 6e-61
sp|Q00291|OTC_ASPTE ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OT... 233 2e-60
gb|AAF44121.1|AF241726_1 (AF241726) ornithine transcarbamylase [... 233 2e-60
sp|P14995|OTC_PACTA ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OT... 232 5e-60
pir||T49353 probable ornithine carbamoyltransferase precursor [i... 231 8e-60
sp|P21302|OTCC_NEIGO ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC (... 230 2e-59
sp|Q46169|OTCC_CLOPE ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC (... 230 2e-59
gi|6322373 Ornithine carbamoyltransferase; Arg3p [Saccharomyces ... 228 5e-59
pir||OWBY ornithine carbamoyltransferase (EC 2.1.3.3) - yeast (... 228 5e-59
gb|AAD01405.1| (AF007428) ornithine carbamoyltransferase homolog... 228 7e-59
sp|P08308|OTCC_PSEAE ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC (... 225 6e-58
sp|P44770|OTCC_HAEIN ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC (... 223 2e-57
pdb|1ORT|A Chain A, Ornithine Transcarbamoylase From Pseudomonas... 223 2e-57
emb|CAB75986.1| (AJ272085) ornithine carbamoyltransferase [Staph... 220 1e-56
sp|P04391|OTC1_ECOLI ORNITHINE CARBAMOYLTRANSFERASE CHAIN I (OTC... 219 3e-56
pdb|1DUV|G Chain G, Crystal Structure Of E. Coli Ornithine Trans... 219 3e-56
pdb|2OTC|A Chain A, Ornithine Transcarbamoylase Complexed With N... 217 1e-55
sp|P06960|OTC2_ECOLI ORNITHINE CARBAMOYLTRANSFERASE CHAIN F (OTC... 214 1e-54
emb|CAA25329.1| (X00759) OTCase [Escherichia coli] 212 5e-54
sp|P23752|OTCC_PSESH ORNITHINE CARBAMOYLTRANSFERASE, PHASEOLOTOX... 205 5e-52
emb|CAA25037.1| (X00210) coding sequence argI gene [Escherichia ... 205 8e-52
gb|AAC28939.1| (AF069576) ornithine carbamoyltransferase [Giardi... 205 8e-52
prf||1707278A Orn carbamoyltransferase [Pseudomonas syringae pv.... 204 1e-51
emb|CAA39136.1| (X55520) phaseolotoxin-insensitive ornithine car... 204 1e-51
sp|P78605|OTC_CORHI ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OT... 203 3e-51
dbj|BAA05061.1| (D26062) ornithine carbamoyltransferase [Coriolu... 202 4e-51
gi|11420218 similar to ornithine carbamoyltransferase (H. sapien... 202 4e-51
sp|P57449|OTCA_BUCAI ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (O... 199 3e-50
pir||S24720 ornithine carbamoyltransferase (EC 2.1.3.3) - Neisse... 198 1e-49
sp|Q01324|OTCC_NEILA ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC (... 179 3e-44
pir||S24734 ornithine carbamoyltransferase (EC 2.1.3.3) - Neisse... 178 7e-44
sp|P75473|OTCC_MYCPN ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC (... 172 4e-42
pir||F82737 ornithine carbamoyltransferase XF0998 [imported] - X... 171 9e-42
emb|CAA66276.1| (X97684) ornithine carbamoyl transferase [Clostr... 153 2e-36
emb|CAA60100.1| (X86157) ornithine carbamoyltransferase [Coryneb... 151 9e-36
pir||A81238 aspartate carbamoyltransferase (EC 2.1.3.2) catalyti... 139 4e-32
sp|Q08016|OTC1_SALTY ORNITHINE CARBAMOYLTRANSFERASE CHAIN I (OTC... 138 7e-32
sp|O58451|PYRB_PYRHO ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE T... 130 3e-29
sp|P77918|PYRB_PYRAB ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE T... 129 3e-29
sp|Q91437|PYR1_SQUAC CAD PROTEIN [INCLUDES: GLUTAMINE-DEPENDENT ... 128 1e-28
pir||A36240 pyrimidine synthesis protein CAD - human (fragment) ... 127 1e-28
gi|4757896 carbamoyl-phosphate synthetase 2, aspartate transcarb... 127 1e-28
sp|P08955|PYR1_MESAU CAD PROTEIN [INCLUDES: GLUTAMINE-DEPENDENT ... 125 7e-28
gb|AAA37064.1| (M23652) CAD protein [Mesocricetus auratus] 125 7e-28
sp|P96174|PYRB_VIBS2 ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CH... 123 3e-27
sp|Q58976|PYRB_METJA ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE T... 122 4e-27
emb|CAC11715.1| (AL445064) probable aspartate carbamoyltransfera... 122 4e-27
pir||D75435 aspartate carbamoyltransferase - Deinococcus radiodu... 122 6e-27
sp|P05654|PYRB_BACSU ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE T... 121 1e-26
pdb|2AT2|A Chain A, Aspartate Transcarbamoylase (E.C.2.1.3.2) (A... 121 1e-26
emb|CAA32782.1| (X14634) PYR1-3B multifunctional enzyme (1014 AA... 120 2e-26
pir||QZDOP3 pyrimidine synthesis protein PYR1-3 - slime mold (D... 120 2e-26
sp|P20054|PYR1_DICDI PROTEIN PYR1-3 [INCLUDES: GLUTAMINE-DEPENDE... 120 2e-26
gb|AAF48639.2| (AE003503) CG18572 gene product [Drosophila melan... 120 2e-26
sp|P49077|PYRB_ARATH ASPARTATE CARBAMOYLTRANSFERASE PRECURSOR (A... 119 5e-26
dbj|BAB02813.1| (AB024036) aspartate carbamoyltransferase [Arabi... 118 1e-25
dbj|BAB03303.1| (AB037416) aspartate carbamoyl transferase [Oryz... 117 2e-25
pir||H82066 aspartate carbamoyltransferase, catalytic chain VC25... 116 3e-25
sp|Q43087|PYB2_PEA ASPARTATE CARBAMOYLTRANSFERASE 2 PRECURSOR (A... 116 4e-25
sp|Q43064|PYB3_PEA ASPARTATE CARBAMOYLTRANSFERASE 3 PRECURSOR (A... 116 4e-25
gb|AAD09129.1| (AF112473) PyrABCN [Aspergillus nidulans] 114 1e-24
sp|Q43086|PYB1_PEA ASPARTATE CARBAMOYLTRANSFERASE 1 PRECURSOR (A... 114 2e-24
gb|AAA68280.1| (M27174) carbamyl phosphate synthetase [Saccharom... 112 5e-24
emb|CAA60825.1| (X87371) carbamyl phosphate synthetase [Saccharo... 112 5e-24
gi|6322331 carbamoyl-phophate synthetase, aspartate transcarbamy... 112 5e-24
gb|AAG21801.1|AF192346_1 (AF192346) aspartate transcarbamoylase ... 112 6e-24
gb|AAB86625.1| (AF031144) aspartate transcarbamoylase [Plasmodiu... 109 3e-23
dbj|BAA94298.1| (AB029444) Aspartate carbamoyltransferase [Leish... 109 5e-23
pir||H83595 aspartate carbamoyltransferase PA0402 [imported] - P... 108 9e-23
sp|Q59653|PYRB_PSEAE ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE T... 108 1e-22
sp|P96079|PYRB_THEAQ ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE T... 107 2e-22
gb|AAG20942.1| (AE005160) aspartate carbamoyltransferase catalyt... 107 2e-22
sp|Q09794|PYR1_SCHPO URA1 PROTEIN [INCLUDES: GLUTAMINE-DEPENDENT... 106 4e-22
pir||T30522 aspartate carbamoyltransferase (EC 2.1.3.2) - Trypan... 106 4e-22
dbj|BAA22792.1| (AB007852) aspartate carbamoyltransferase [Trypa... 105 6e-22
gb|AAG15558.1| (AY007523) aspartate carbamoyl transferase PyrB [... 105 6e-22
gb|AAA24476.1| (K01472) aspartate transcarbamoylase catalytic ch... 104 1e-21
sp|P00479|PYRB_ECOLI ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CH... 104 1e-21
gb|AAA97142.1| (U14003) aspartate carbomoyltransferase catalytic... 104 1e-21
sp|Q59711|PYRB_PSEPU ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE T... 104 2e-21
pir||S35212 aspartate carbamoyltransferase (EC 2.1.3.2) - tomato... 104 2e-21
sp|P08420|PYRB_SALTY ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CH... 103 2e-21
pir||S42709 aspartate carbamoyltransferase (EC 2.1.3.2) - tomato... 103 3e-21
sp|P41008|PYRB_BACCL ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE T... 102 5e-21
pir||I40166 aspartate carbamoyltransferase (EC 2.1.3.2) - Bacill... 102 5e-21
pir||T20371 hypothetical protein D2085.1 - Caenorhabditis elegan... 102 5e-21
gb|AAA24474.1| (J01670) aspartate transcarbamoylase catalytic ch... 102 7e-21
sp|P19910|PYRB_SERMA ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CH... 101 9e-21
gb|AAF01338.1|AF190426_2 (AF190426) aspartate transcarbamylase c... 101 2e-20
pir||OWEBAC aspartate carbamoyltransferase (EC 2.1.3.2) catalyti... 100 3e-20
pir||S65074 pyrimidine synthesis protein URA1 - fission yeast (... 100 3e-20
pir||C72547 probable aspartate carbamoyltransferase catalytic ch... 99 5e-20
sp|P57450|PYRB_BUCAI ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CH... 99 5e-20
gb|AAA37009.1| (M33702) dihydroorotase synthetase complex (EC 3.... 99 8e-20
gb|AAA35198.1| (J04711) carbamylase phosphate synthetase-asparta... 96 5e-19
emb|CAB89871.1| (AJ132624) aspartate transcarbamoylase [Lactococ... 95 9e-19
sp|O25716|PYRB_HELPY ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE T... 95 1e-18
sp|P74163|PYRB_SYNY3 ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE T... 92 8e-18
pir||C33917 pyrimidine synthesis protein CAD - Chinese hamster ... 92 1e-17
sp|Q55338|PYRB_SULAC ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE T... 92 1e-17
sp|P16964|OTCX_STRPY PROBABLE ORNITHINE CARBAMOYLTRANSFERASE (OTC) 88 1e-16
pir||PE0009 ornithine carbamoyltransferase homolog - Streptococc... 88 2e-16
sp|P05990|PYR1_DROME CAD PROTEIN (RUDIMENTARY PROTEIN) [INCLUDES... 87 2e-16
emb|CAB93367.1| (AL357523) aspartate carbamoyltransferase [Strep... 86 5e-16
gb|AAF72727.1| (AF264709) aspartate transcarbamoylase [Enterococ... 83 3e-15
gb|AAK40925.1| Aspartate carbamoyltransferase catalytic chain (A... 80 3e-14
sp|Q9UX08|PYRB_SULSO ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE T... 80 3e-14
pir||S47625 aspartate carbamoyltransferase (EC 2.1.3.2) - wheat ... 78 1e-13
sp|Q60252|PYRB_LACLE ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE T... 75 9e-13
>sp|O93656|OTC_PYRAB ORNITHINE CARBAMOYLTRANSFERASE (OTCASE) >gi|7433600|pir||G75041
ornithine carbamoyltransferase (argf) PAB1502 -
Pyrococcus abyssi (strain Orsay)
>gi|5458741|emb|CAB50228.1| (AJ248287) ornithine
carbamoyltransferase (argF) [Pyrococcus abyssi]
Length = 317
Score = 647 bits (1650), Expect = 0.0
Identities = 317/317 (100%), Positives = 317/317 (100%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT
Sbjct: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK
Sbjct: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA 180
YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA
Sbjct: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA 180
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE
Sbjct: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH
Sbjct: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
Query: 301 AQKAVLALLLGGVKTGF 317
AQKAVLALLLGGVKTGF
Sbjct: 301 AQKAVLALLLGGVKTGF 317
>sp|O58457|OTC_PYRHO ORNITHINE CARBAMOYLTRANSFERASE (OTCASE) >gi|7433591|pir||G71119
probable ornithine carbamoyltransferase - Pyrococcus
horikoshii >gi|3257134|dbj|BAA29817.1| (AP000003) 317aa
long hypothetical ornithine carbamoyltransferase
[Pyrococcus horikoshii]
Length = 317
Score = 636 bits (1622), Expect = 0.0
Identities = 312/317 (98%), Positives = 313/317 (98%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
MVVSLKGRDLLCLQDYTPEEIWTILETAKM KIWQKIGKPHRLLEGKTLAMIFQKPSTRT
Sbjct: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMFKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVY HKDVEDLAK
Sbjct: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYAHKDVEDLAK 120
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA 180
YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNV HSLMIAGTKLGA
Sbjct: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVCHSLMIAGTKLGA 180
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
DVVVATPEGYEPD+KVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE
Sbjct: 181 DVVVATPEGYEPDKKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
AEERRKIFRPFQVNKDLVKHAK DYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH
Sbjct: 241 AEERRKIFRPFQVNKDLVKHAKSDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
Query: 301 AQKAVLALLLGGVKTGF 317
AQKAVLALLLGGVKTGF
Sbjct: 301 AQKAVLALLLGGVKTGF 317
>gb|AAD09004.1| (AF083209) ornithine carbamoyltransferase [Pyrococcus abyssi]
Length = 320
Score = 631 bits (1609), Expect = e-180
Identities = 308/316 (97%), Positives = 311/316 (97%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT
Sbjct: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
RV FEVAMAHLGGH LYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK
Sbjct: 61 RVRFEVAMAHLGGHGLYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA 180
YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKV+YVGDGNNVAHSLMIAGTKLGA
Sbjct: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVIYVGDGNNVAHSLMIAGTKLGA 180
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
DVVVATPEGYEPDEKVIKWA++NAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE
Sbjct: 181 DVVVATPEGYEPDEKVIKWADENAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
AEERRKIFRPFQVNKDLVKHAKP YMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH
Sbjct: 241 AEERRKIFRPFQVNKDLVKHAKPSYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
Query: 301 AQKAVLALLLGGVKTG 316
AQKAVLALLLGG K G
Sbjct: 301 AQKAVLALLLGGRKDG 316
>pdb|1A1S| Ornithine Carbamoyltransferase From Pyrococcus Furiosus
Length = 314
Score = 626 bits (1598), Expect = e-179
Identities = 305/313 (97%), Positives = 310/313 (98%)
Query: 2 VVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTR 61
VVSL GRDLLCLQDYT EEIWTILETAKM KIWQKIGKPHRLLEGKTLAMIFQKPSTRTR
Sbjct: 1 VVSLAGRDLLCLQDYTAEEIWTILETAKMFKIWQKIGKPHRLLEGKTLAMIFQKPSTRTR 60
Query: 62 VSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKY 121
VSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKY
Sbjct: 61 VSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKY 120
Query: 122 ASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGAD 181
A+VPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGAD
Sbjct: 121 ATVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGAD 180
Query: 182 VVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA 241
VVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA
Sbjct: 181 VVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA 240
Query: 242 EERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHA 301
EERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWD+AENRLHA
Sbjct: 241 EERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDQAENRLHA 300
Query: 302 QKAVLALLLGGVK 314
QKAVLAL++GG+K
Sbjct: 301 QKAVLALVMGGIK 313
>sp|Q51742|OTC_PYRFU ORNITHINE CARBAMOYLTRANSFERASE (OTCASE) >gi|3341473|emb|CAA73260.1|
(Y12727) ornithine carbamoyltransferase [Pyrococcus
furiosus]
Length = 315
Score = 624 bits (1592), Expect = e-178
Identities = 304/314 (96%), Positives = 309/314 (97%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
MVVSL GRDLLCLQDYT EEIWTILETAKM KIWQKIGKPHRLLEGKTLAMIFQKPSTRT
Sbjct: 1 MVVSLAGRDLLCLQDYTAEEIWTILETAKMFKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK
Sbjct: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA 180
YA+VPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA
Sbjct: 121 YATVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA 180
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
DVVVATPEGYEPDEKVIKWAEQNAAE GSFELLHDPVKAVKDADVIYTDVWASMGQEAE
Sbjct: 181 DVVVATPEGYEPDEKVIKWAEQNAAERSGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWD+AENRLH
Sbjct: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDQAENRLH 300
Query: 301 AQKAVLALLLGGVK 314
AQKAVLAL++GG+K
Sbjct: 301 AQKAVLALVMGGIK 314
>pir||T45077 ornithine carbamoyltransferase [imported] - Pyrococcus furiosus
>gi|1430923|emb|CAA67609.1| (X99225) ornithine
carbamoyltransferase [Pyrococcus furiosus]
Length = 314
Score = 621 bits (1585), Expect = e-177
Identities = 305/314 (97%), Positives = 310/314 (98%), Gaps = 1/314 (0%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
MVVSL GRDLLCLQDYT EEIWTILETAKM KIWQKIGKPHRLLEGKTLAMIFQKPSTRT
Sbjct: 1 MVVSLAGRDLLCLQDYTAEEIWTILETAKMFKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK
Sbjct: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA 180
YA+VPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA
Sbjct: 121 YATVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA 180
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
DVVVATPEGYEPDEKVIKWAEQNAAES GSFELLHDPVKAVKDADVIYTDVWASMGQEAE
Sbjct: 181 DVVVATPEGYEPDEKVIKWAEQNAAES-GSFELLHDPVKAVKDADVIYTDVWASMGQEAE 239
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWD+AENRLH
Sbjct: 240 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDQAENRLH 299
Query: 301 AQKAVLALLLGGVK 314
AQKAVLAL++GG+K
Sbjct: 300 AQKAVLALVMGGIK 313
>dbj|BAB06613.1| (AP001517) ornithine carbamoyltransferase [Bacillus halodurans]
Length = 319
Score = 372 bits (946), Expect = e-102
Identities = 188/311 (60%), Positives = 228/311 (72%)
Query: 2 VVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTR 61
V+SLKGRDLL L DYTPEE+ +L A LK K G+P L GK+L MIF+ STRTR
Sbjct: 8 VISLKGRDLLTLLDYTPEEVQQLLTQALELKQKAKNGEPTPYLTGKSLGMIFENASTRTR 67
Query: 62 VSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKY 121
VSFEV M LGGHAL+L+ +DLQ+ RGE I DTA VLSRYVDAIM R H+ VE+LA Y
Sbjct: 68 VSFEVGMTQLGGHALFLSPKDLQIGRGEPIKDTANVLSRYVDAIMIRTNSHESVEELAHY 127
Query: 122 ASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGAD 181
A+VPVIN L+D HPCQALAD +TI EKK T+ G K+ Y+GDGNNV HSL+ G K G D
Sbjct: 128 ATVPVINALTDAYHPCQALADALTILEKKETLIGKKLAYIGDGNNVCHSLLAIGAKTGMD 187
Query: 182 VVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA 241
V VATP+GYE D+++ + A + A E+G + +P A ++AD IYTDVWASMG EAE
Sbjct: 188 VTVATPKGYEVDQEIFQRATEAAKETGATLVQTTNPQVAAENADAIYTDVWASMGYEAEQ 247
Query: 242 EERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHA 301
ER ++F+P+QVN L+ AK D F+HCLPAHRGEEVT VID P+S ++D+AENRLHA
Sbjct: 248 SEREEVFQPYQVNDQLLTLAKKDVSFLHCLPAHRGEEVTASVIDGPHSAIYDQAENRLHA 307
Query: 302 QKAVLALLLGG 312
QKAVL LL G
Sbjct: 308 QKAVLTALLIG 318
>sp|P18186|OTCA_BACSU ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (OTCASE)
>gi|66493|pir||OWBS ornithine carbamoyltransferase (EC
2.1.3.3) - Bacillus subtilis >gi|39811|emb|CAA37444.1|
(X53360) argF protein (AA 1 - 319) [Bacillus subtilis]
>gi|408120|emb|CAA81542.1| (Z26919) ornithine
carbamoyltransferase [Bacillus subtilis]
>gi|2633462|emb|CAB12966.1| (Z99109) ornithine
carbamoyltransferase [Bacillus subtilis]
>gi|2633479|emb|CAB12982.1| (Z99110) ornithine
carbamoyltransferase [Bacillus subtilis]
Length = 319
Score = 367 bits (932), Expect = e-100
Identities = 186/307 (60%), Positives = 231/307 (74%), Gaps = 4/307 (1%)
Query: 4 SLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVS 63
SL G+DLL L+D + E+I +L A LK K + GKTLAMIF+K STRTRVS
Sbjct: 8 SLYGKDLLTLKDLSEEDINALLAEAGELKQ----NKIQPIFHGKTLAMIFEKSSTRTRVS 63
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
FE MA LGG AL+L+ +DLQL RGET+ADTA+VLS YVDAIM R ++H+ VE+LAK A
Sbjct: 64 FEAGMAQLGGSALFLSQKDLQLGRGETVADTAKVLSGYVDAIMIRTFEHEKVEELAKEAD 123
Query: 124 VPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVV 183
+PVINGL+D HPCQALAD +TI E KG +KGVKV Y+GDGNNVAHSLMI K+G D+
Sbjct: 124 IPVINGLTDKYHPCQALADLLTIKEIKGKLKGVKVAYIGDGNNVAHSLMIGCAKMGCDIS 183
Query: 184 VATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEE 243
+A+P+GYE ++ + A+ A +SG S L DP++AVKDADVIY+DV+ SMGQEAE +E
Sbjct: 184 IASPKGYEVLDEAAEAAKTYALQSGSSVTLTDDPIEAVKDADVIYSDVFTSMGQEAEEQE 243
Query: 244 RRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQK 303
R +F P+QVN LV HAKPDY F+HCLPAHR EEVT ++ID PNS V+ +AENRLH QK
Sbjct: 244 RLAVFAPYQVNAALVSHAKPDYTFLHCLPAHREEEVTAEIIDGPNSAVFQQAENRLHVQK 303
Query: 304 AVLALLL 310
A+L +L
Sbjct: 304 ALLKAIL 310
>gb|AAC78720.1| (U43091) ornithine carbamoyltransferase [Bacillus
stearothermophilus]
Length = 311
Score = 363 bits (921), Expect = 2e-99
Identities = 183/309 (59%), Positives = 232/309 (74%), Gaps = 1/309 (0%)
Query: 2 VVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTR 61
V+SLKGRD L L D++ EEI +L A LK QK G + L GKT+AMIF+KPS TR
Sbjct: 4 VMSLKGRDFLTLLDFSTEEILDLLALAADLKAKQKAGVSYTPLSGKTMAMIFEKPSG-TR 62
Query: 62 VSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKY 121
VSFEV M LGG A+YLN LQL RGETIADTARVLS+YV IM R + H+ VE+LA+Y
Sbjct: 63 VSFEVGMIQLGGQAMYLNGNHLQLGRGETIADTARVLSQYVRVIMIRTFAHQKVEELAEY 122
Query: 122 ASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGAD 181
AS NGL+D HPCQALAD +TI+E K T +GVK+ YVGDGNNVA++L++A K+G D
Sbjct: 123 ASFRSSNGLTDDDHPCQALADLLTIYEVKKTFQGVKLAYVGDGNNVANALLVAAAKVGMD 182
Query: 182 VVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA 241
V +A P GYEP ++ ++ A + ++G + HDP+ AV AD IYTDVW SMGQE+E+
Sbjct: 183 VAIACPPGYEPKKEYVEAACRVGEQTGRRVTVTHDPLVAVAGADRIYTDVWTSMGQESES 242
Query: 242 EERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHA 301
ER ++F+P+QVN++LVK AKPDY+F+HCLPAHRGEEVT V+D PNSVV+++A NRLHA
Sbjct: 243 SERLQVFQPYQVNEELVKAAKPDYLFLHCLPAHRGEEVTAGVMDGPNSVVFEQAGNRLHA 302
Query: 302 QKAVLALLL 310
QKA+L +L
Sbjct: 303 QKAILLSVL 311
>pir||B72502 probable ornithine carbamoyltransferase APE1992 - Aeropyrum pernix
(strain K1) >gi|5105690|dbj|BAA81002.1| (AP000063) 402aa
long hypothetical ornithine carbamoyltransferase
[Aeropyrum pernix]
Length = 402
Score = 351 bits (891), Expect = 6e-96
Identities = 174/308 (56%), Positives = 236/308 (76%), Gaps = 2/308 (0%)
Query: 5 LKGRDLLCLQDYTPEEIWTILE-TAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVS 63
L+GR LL L DYT EEI ++E T +M + + + +L G+++ ++F+KPSTRTR+S
Sbjct: 94 LRGRHLLWLADYTGEEIRHMVELTLEMKRRYYAGERVIPVLRGRSVGLLFEKPSTRTRIS 153
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
EVA+A LGGH +Y+ + QL RGET+ADTARVLSRY+DAI+ARV HK +E++A++AS
Sbjct: 154 LEVAVAQLGGHTVYMTPSETQLGRGETVADTARVLSRYLDAIVARVRSHKTLEEMARHAS 213
Query: 124 VPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLGADV 182
+PVINGLSD +HP QA+AD TI EKKG ++GVK+ +VGDG +NV HSL++AG+KLG +
Sbjct: 214 IPVINGLSDLTHPLQAIADMATILEKKGRLEGVKLAFVGDGADNVLHSLLLAGSKLGLHI 273
Query: 183 VVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAE 242
VATP PDE+++ A + A ESGGS E++ DP +AV+ ADV+YTDVW SMGQE+ AE
Sbjct: 274 TVATPPQIRPDERILSIALKAAEESGGSVEIVSDPYEAVRGADVVYTDVWVSMGQESMAE 333
Query: 243 ERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQ 302
E+ ++ +P+QVN L++ +FMHCLPA RG+EVTD+VID P S VWD+AENRLHA
Sbjct: 334 EKVQLLKPYQVNAKLMEATGGRAIFMHCLPAKRGQEVTDEVIDGPWSAVWDQAENRLHAH 393
Query: 303 KAVLALLL 310
KAVL+LL+
Sbjct: 394 KAVLSLLV 401
>gi|11498854 ornithine carbamoyltransferase (argF) [Archaeoglobus fulgidus]
>gi|3183096|sp|O29013|OTC_ARCFU ORNITHINE
CARBAMOYLTRANSFERASE (OTCASE) >gi|7433595|pir||F69406
ornithine carbamoyltransferase (argF) homolog -
Archaeoglobus fulgidus >gi|2649323|gb|AAB89987.1|
(AE001017) ornithine carbamoyltransferase (argF)
[Archaeoglobus fulgidus]
Length = 307
Score = 340 bits (863), Expect = 1e-92
Identities = 167/304 (54%), Positives = 224/304 (72%), Gaps = 4/304 (1%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
+ LL + D +E++ IL+ A+ LK + G L+ K+LAMIF+ PSTRTRVSFEVA
Sbjct: 2 KHLLSMADLEKDELFEILKLAEKLKEERYKGVVTDYLKNKSLAMIFELPSTRTRVSFEVA 61
Query: 68 MAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVI 127
M LGGHALYL +LQL RGE I DTARVLSRYV A+M RV +H +E+ A+Y++VPVI
Sbjct: 62 MTDLGGHALYLGWDELQLGRGEPIKDTARVLSRYVHAVMMRVREHSTIEEFARYSTVPVI 121
Query: 128 NGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVVATP 187
NGLS+ HPCQ +AD +TI+E +G K V + +VGDGNNV +S+++A G +V++TP
Sbjct: 122 NGLSNLEHPCQVIADLLTIYEYRGDFKDVTLAWVGDGNNVCNSMILAAALTGMKMVISTP 181
Query: 188 EGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRKI 247
E Y+P+ +++K AE E G + DP +AVK+ADVIYTDVW SMGQEAE E R K
Sbjct: 182 ENYDPNPEIVKKAE----EMGAKLRFVRDPKEAVKEADVIYTDVWTSMGQEAEKEARLKA 237
Query: 248 FRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVLA 307
F+P+QV+ +L+K +K D + MHCLPAHRGEE+TD+V++ +S+V+D+AENRLHAQKA+L
Sbjct: 238 FQPYQVSDELLKFSKDDVVVMHCLPAHRGEEITDEVMEGKHSIVFDQAENRLHAQKAILL 297
Query: 308 LLLG 311
LLG
Sbjct: 298 KLLG 301
>sp|O27495|OTC_METTH ORNITHINE CARBAMOYLTRANSFERASE (OTCASE) >gi|7433596|pir||E69059
ornithine carbamoyltransferase - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622559|gb|AAB85921.1| (AE000906) ornithine
carbamoyltransferase [Methanobacterium
thermoautotrophicum]
Length = 301
Score = 331 bits (840), Expect = 6e-90
Identities = 164/272 (60%), Positives = 203/272 (74%), Gaps = 1/272 (0%)
Query: 42 RLLEGKTLAMIFQKPSTRTRVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRY 101
++L GKTLAMIF+K STRTRVSFEV +G LYL+A DLQL RGE IADTAR LSRY
Sbjct: 31 KILRGKTLAMIFEKSSTRTRVSFEVGAFQMGAQPLYLSASDLQLGRGEPIADTARTLSRY 90
Query: 102 VDAIMARVYDHKDVEDLAKYASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYV 161
VD IM R H DV +LA ASVPVINGL+D HPCQALAD TI EK G G ++V+V
Sbjct: 91 VDGIMIRAISHSDVVELAGEASVPVINGLTDLEHPCQALADMQTIREKLGGFDG-RLVFV 149
Query: 162 GDGNNVAHSLMIAGTKLGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAV 221
GDGNNV HSL++ LG D+ VA P GYEPD + + A + A E+G ++HDP +AV
Sbjct: 150 GDGNNVCHSLLLITATLGMDMDVACPPGYEPDPGIREMAGKIADETGSRIRVIHDPSEAV 209
Query: 222 KDADVIYTDVWASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTD 281
+ ADV+YTDVW SMG E EAE+R ++FRP+QVN +L++ A P+ +FMHCLPA RG+E T
Sbjct: 210 RGADVVYTDVWVSMGYEDEAEDRLEVFRPYQVNMELMELAAPEAIFMHCLPAVRGQETTA 269
Query: 282 DVIDSPNSVVWDEAENRLHAQKAVLALLLGGV 313
+VID P+SVVWD+AENRLHAQKA++ L+G +
Sbjct: 270 EVIDGPHSVVWDQAENRLHAQKAIMHWLMGDI 301
>sp|Q58291|OTC_METJA ORNITHINE CARBAMOYLTRANSFERASE (OTCASE) >gi|2129172|pir||A64410
ornithine carbamoyltransferase (EC 2.1.3.3) -
Methanococcus jannaschii >gi|1592314|gb|AAB98885.1|
(U67532) ornithine carbamoyltransferase (argF)
[Methanococcus jannaschii]
Length = 305
Score = 323 bits (819), Expect = 2e-87
Identities = 158/301 (52%), Positives = 218/301 (71%), Gaps = 3/301 (0%)
Query: 10 LLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAMA 69
LL L + E++ I+E K ++ K ++LEGK++A++F+KPSTRTR+SF++A+
Sbjct: 3 LLDLDVLSREDVLKIIEYGIYFKKNRR--KHEKILEGKSVAILFEKPSTRTRMSFDIAVY 60
Query: 70 HLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVING 129
LGGH L +N ++ L + E+I DTA+V+ RYVD I+ARVY H+ +E++AKY+SVPVIN
Sbjct: 61 ELGGHPLIMNQNEIHLGKKESIKDTAKVMGRYVDTIVARVYKHRHLEEMAKYSSVPVINA 120
Query: 130 LSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVVATPEG 189
LSD +HPCQ LAD MTI E KG KG+K+ Y+GDGNNV +SL++ +G D V TP+G
Sbjct: 121 LSDLAHPCQILADLMTIKEYKGKFKGLKIAYLGDGNNVCNSLILGSALVGMDTYVGTPKG 180
Query: 190 YEPDEKVIKWAEQNAAESG-GSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRKIF 248
YEP+ KV+ A++ G GS L +DP++A +DADV+YTDVW SMG + + EE KIF
Sbjct: 181 YEPNAKVVLKAKEIINNYGEGSLTLTNDPIEAAEDADVLYTDVWISMGDDKDKEEVLKIF 240
Query: 249 RPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVLAL 308
PFQ+N L+++AK D + MHCLPA+RG E+TDDVID +SVV+DEAENRLH QK V
Sbjct: 241 PPFQINSKLLEYAKDDVIVMHCLPANRGYEITDDVIDGEHSVVYDEAENRLHVQKGVFKF 300
Query: 309 L 309
+
Sbjct: 301 I 301
>emb|CAC12451.1| (AL445067) probable ornithine carbamoyltransferase [Thermoplasma
acidophilum]
Length = 297
Score = 322 bits (816), Expect = 4e-87
Identities = 153/272 (56%), Positives = 202/272 (74%)
Query: 39 KPHRLLEGKTLAMIFQKPSTRTRVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVL 98
+ + L K L +IF+KPSTRTR S EVA+ LGGHA+YLN ++QL RGETI+DT VL
Sbjct: 24 RSYESLRNKVLGLIFEKPSTRTRTSLEVAIDQLGGHAVYLNPSEMQLGRGETISDTGHVL 83
Query: 99 SRYVDAIMARVYDHKDVEDLAKYASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKV 158
SR++DAI R YDH++V +LA+ S+PVIN L D HP Q +AD+MTI EKKG +K
Sbjct: 84 SRFLDAIAYRAYDHRNVVELARSTSIPVINALDDVEHPLQIVADFMTIKEKKGRFTNLKF 143
Query: 159 VYVGDGNNVAHSLMIAGTKLGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPV 218
Y+GDGNN+A+SLM+ LG D+ VA+P+G+EP ++ ++ A A + G S + +DPV
Sbjct: 144 SYIGDGNNMANSLMLGAAILGTDMYVASPKGFEPKQEFVEKARSIAKQHGSSITITNDPV 203
Query: 219 KAVKDADVIYTDVWASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEE 278
+A +DADVIYTDVW SMG+E++ E+ K F+ FQ+N+ LV +AK DY+FMHCLPAHRG E
Sbjct: 204 EAARDADVIYTDVWISMGEESKKGEKEKAFKDFQINEKLVSNAKRDYIFMHCLPAHRGLE 263
Query: 279 VTDDVIDSPNSVVWDEAENRLHAQKAVLALLL 310
VTD V DS NSV++DEAENRLH++K VL LL
Sbjct: 264 VTDGVADSINSVIFDEAENRLHSEKGVLYKLL 295
>gb|AAF17705.1|AF033562_1 (AF033562) ornithine carbamoyltransferase; OCTase [Canavalia
lineata]
Length = 359
Score = 306 bits (775), Expect = 3e-82
Identities = 154/305 (50%), Positives = 211/305 (68%), Gaps = 4/305 (1%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIG-KPHRLLEGKTLAMIFQKPSTRTRVSFEV 66
++ L L D+ + I +L+ A +K K G + R EGKT++MIF KPS RTRVSFE
Sbjct: 57 KNFLHLDDFDKDTILKMLDRALEVKSLLKSGDRTFRPFEGKTMSMIFTKPSMRTRVSFET 116
Query: 67 AMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPV 126
LGGHA+YL D+Q+ + E D ARVLSRY D IMARV+ H+D+ DLAKYA+VPV
Sbjct: 117 GFTLLGGHAIYLGPDDIQMGKREETRDVARVLSRYNDIIMARVFAHQDILDLAKYATVPV 176
Query: 127 INGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVVAT 186
INGL+D++HPCQ +AD +T+ E G +G KVVYVGDGNN+ HS ++ + + V A
Sbjct: 177 INGLTDYNHPCQIMADALTMIEHIGRFEGTKVVYVGDGNNIVHSWLLMASVIPFHFVCAC 236
Query: 187 PEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRK 246
P+G+EPD K ++ A + E+ +DP +AVK ADV+Y+DVWASMGQ+ EA RR+
Sbjct: 237 PKGFEPDAKTVEKARKAGI---SKIEITNDPKEAVKGADVVYSDVWASMGQKEEAAHRRE 293
Query: 247 IFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVL 306
+F+ FQV+ +L+ A FMHCLPA RG EVTD+V+++ NS+V+ +AENR+HAQ AV+
Sbjct: 294 VFKGFQVDHNLMNIAGSKAFFMHCLPAERGVEVTDEVVEASNSIVFPQAENRMHAQNAVM 353
Query: 307 ALLLG 311
+LG
Sbjct: 354 LHVLG 358
>sp|Q43814|OTC_PEA ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OTCASE) (ORNITHINE
TRANSCARBAMYLASE) >gi|7433603|pir||T06436 probable
ornithine carbamoyltransferase (EC 2.1.3.3) - garden pea
>gi|971168|gb|AAA74997.1| (U13684) ornithine
carbamoyltransferase [Pisum sativum]
Length = 375
Score = 305 bits (774), Expect = 3e-82
Identities = 154/305 (50%), Positives = 210/305 (68%), Gaps = 4/305 (1%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIG-KPHRLLEGKTLAMIFQKPSTRTRVSFEV 66
+D + + D+ E I IL+ A +K K G + R EGKT++MIF KPS RTRVSFE
Sbjct: 73 KDFIHIDDFDKETILKILDRAIEVKTLLKSGDRTFRPFEGKTMSMIFAKPSMRTRVSFET 132
Query: 67 AMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPV 126
+ LGGHA+YL D+Q+ + E D ARVLSRY D IMARV+ H+D+ DLAKYASVPV
Sbjct: 133 GFSLLGGHAIYLGPNDIQMGKREETRDVARVLSRYNDIIMARVFSHQDILDLAKYASVPV 192
Query: 127 INGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVVAT 186
INGL+D++HP Q +AD +T+ E G +G KVVYVGDGNN+ HS ++ + V A
Sbjct: 193 INGLTDYNHPVQIMADALTMIEHIGRFEGTKVVYVGDGNNIVHSWLLLAAVVPFHFVCAC 252
Query: 187 PEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRK 246
P+G+EPD K ++ A + E+ HDP +AV+ ADV+Y+DVWASMGQ+ EA RR+
Sbjct: 253 PKGFEPDAKTVEKARKAGI---SKIEISHDPKEAVRGADVVYSDVWASMGQKEEAAYRRE 309
Query: 247 IFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVL 306
F+ FQV+++L+ A FMHCLPA RG EVTD+V+++P S+V+ +AENR+HAQ A++
Sbjct: 310 AFKGFQVDQNLMDAAGSKAFFMHCLPAERGVEVTDEVVEAPYSIVFPQAENRMHAQNAIM 369
Query: 307 ALLLG 311
+LG
Sbjct: 370 LHVLG 374
>sp|Q55497|OTCA_SYNY3 ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (OTCASE)
>gi|7433594|pir||S76000 hypothetical protein -
Synechocystis sp. (strain PCC 6803)
>gi|1001360|dbj|BAA10847.1| (D64006) ornithine
carbamoyltransferase chain f [Synechocystis sp.]
Length = 308
Score = 305 bits (773), Expect = 4e-82
Identities = 156/310 (50%), Positives = 210/310 (67%), Gaps = 6/310 (1%)
Query: 2 VVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTR 61
+ +L GRDLL + D T EE+ ++L+ A LK + KPH K L ++F K STRTR
Sbjct: 3 IKALAGRDLLAIADLTIEEMKSLLQLAADLK--SGVLKPHCR---KILGLLFYKASTRTR 57
Query: 62 VSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKY 121
VSF AM LGG L LN Q+ RGE I DTARVL RY+D + R + D++ A +
Sbjct: 58 VSFTAAMYQLGGQVLDLNPSVTQVGRGEPIQDTARVLDRYIDILAVRTFKQTDLQTFADH 117
Query: 122 ASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGAD 181
A +P+IN LSD HPCQ LAD TI E G ++G+ V Y+GDGNNVAHSL++ G +G
Sbjct: 118 AKMPIINALSDLEHPCQILADLQTIKECFGKLEGLTVTYLGDGNNVAHSLILGGVMMGMT 177
Query: 182 VVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA 241
V VATP+ YEP ++++ A+Q AA GG EL DP A + + ++YTDVWASMGQE A
Sbjct: 178 VRVATPKNYEPLAEIVQQAQQIAA-PGGKVELTDDPKAAAQGSHILYTDVWASMGQEDLA 236
Query: 242 EERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHA 301
+ R IF+P+Q+N++L+ A P+ + +HCLPAHRGEE+TD V++ P S +WD+AENR+HA
Sbjct: 237 DSRIPIFQPYQINQELLALADPEAIVLHCLPAHRGEEITDAVMEGPQSRLWDQAENRMHA 296
Query: 302 QKAVLALLLG 311
QKA++ LLG
Sbjct: 297 QKALMVALLG 306
>dbj|BAA22924.1| (D86376) ArgF [Bacillus subtilis]
Length = 238
Score = 301 bits (763), Expect = 6e-81
Identities = 145/229 (63%), Positives = 180/229 (78%)
Query: 82 DLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVINGLSDFSHPCQALA 141
DLQL RGET+ADTA+VLS YVDAIM R ++H+ VE+LAK A +PVINGL+D HPCQALA
Sbjct: 1 DLQLGRGETVADTAKVLSGYVDAIMIRTFEHEKVEELAKEADIPVINGLTDKYHPCQALA 60
Query: 142 DYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVVATPEGYEPDEKVIKWAE 201
D +TI E KG +KGVKV Y+GDGNNVAHSLMI K+G D+ +A+P+GYE ++ + A+
Sbjct: 61 DLLTIKEIKGKLKGVKVAYIGDGNNVAHSLMIGCAKMGCDISIASPKGYEVLDEAAEAAK 120
Query: 202 QNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRKIFRPFQVNKDLVKHA 261
A +SG S L DP++AVKDADVIY+DV+ SMGQEAE +ER +F P+QVN LV HA
Sbjct: 121 TYALQSGSSVTLTDDPIEAVKDADVIYSDVFTSMGQEAEEQERLAVFAPYQVNAALVSHA 180
Query: 262 KPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVLALLL 310
KPDY F+HCLPAHR EEVT ++ID PNS V+ +AENRLH QKA+L +L
Sbjct: 181 KPDYTFLHCLPAHREEEVTAEIIDGPNSAVFQQAENRLHVQKALLKAIL 229
>gb|AAG13075.1|AC023754_13 (AC023754) Ornithine carbamoyltransferase [Arabidopsis thaliana]
Length = 375
Score = 301 bits (762), Expect = 8e-81
Identities = 155/305 (50%), Positives = 210/305 (68%), Gaps = 4/305 (1%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRL-LEGKTLAMIFQKPSTRTRVSFEV 66
+D L + D+ I TIL+ A +K K G+ + L +GK+++MIF KPS RTRVSFE
Sbjct: 73 KDFLAIDDFDTATIKTILDKASEVKALLKSGERNYLPFKGKSMSMIFAKPSMRTRVSFET 132
Query: 67 AMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPV 126
LGGHALYL D+Q+ + E D ARVLSRY D IMARV+ H+D+ DLA Y+SVPV
Sbjct: 133 GFFLLGGHALYLGPNDIQMGKREETRDVARVLSRYNDIIMARVFAHQDILDLANYSSVPV 192
Query: 127 INGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVVAT 186
+NGL+D +HPCQ +AD +T+ E G ++G KVVYVGDGNN+ HS + + + V A
Sbjct: 193 VNGLTDHNHPCQIMADALTMIEHIGQVEGTKVVYVGDGNNMVHSWLELASVIPFHFVCAC 252
Query: 187 PEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRK 246
P+GYEPD++ + A+Q E+ +DP +AV ADV+Y+DVWASMGQ+ EAE RRK
Sbjct: 253 PKGYEPDKERVSKAKQAGL---SKIEITNDPKEAVIGADVVYSDVWASMGQKDEAEARRK 309
Query: 247 IFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVL 306
F+ FQV++ L+K A FMHCLPA RG EVT+ V+++P S+V+ +AENR+HAQ A++
Sbjct: 310 AFQGFQVDEALMKLAGQKAYFMHCLPAERGVEVTNGVVEAPYSIVFPQAENRMHAQNAIM 369
Query: 307 ALLLG 311
LLG
Sbjct: 370 LHLLG 374
>gb|AAC36050.1| (AF030524) ornithine carbamoyltransferase; OCT [Nostoc PCC73102]
Length = 306
Score = 299 bits (757), Expect = 3e-80
Identities = 154/312 (49%), Positives = 208/312 (66%), Gaps = 10/312 (3%)
Query: 2 VVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTR 61
+ +L GRDLL L D + E+ +L+ A LK Q +L K L ++F K STRTR
Sbjct: 1 MAALLGRDLLSLADISSTELQELLQLATQLKSQQL-----KLQCNKVLGLLFSKASTRTR 55
Query: 62 VSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKY 121
VSF VAM LGG + LN Q+ RGE + DTARVL RY+D + R + +D+E A Y
Sbjct: 56 VSFTVAMYQLGGQVIDLNPNVTQVSRGEPLQDTARVLDRYLDILAIRTFAQQDLETFAHY 115
Query: 122 ASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGAD 181
A +PVIN L+D HPCQ LAD +TI E T+ G+ + YVGDGNN+A+SLM+ +G +
Sbjct: 116 AKIPVINALTDAEHPCQVLADLLTIQESFNTLAGLTLTYVGDGNNMANSLMLGCALVGMN 175
Query: 182 VVVATPEGYEPDEKVIKWAEQNAAESGGSFELL--HDPVKAVKDADVIYTDVWASMGQEA 239
V +ATP+GYEPD +++ EQ A + E+L HDP A K + V+YTDVWASMGQE
Sbjct: 176 VRIATPDGYEPDSQIV---EQARAIANNKTEVLLTHDPELAAKGSTVLYTDVWASMGQET 232
Query: 240 EAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRL 299
EA+ IF+P+Q+++ L+ A P+ + +HCLPAHRGEE+T+ VI+ S VW++AENRL
Sbjct: 233 EADNSMPIFQPYQISEQLLSLAAPEAIVLHCLPAHRGEEITEAVIEGSQSRVWEQAENRL 292
Query: 300 HAQKAVLALLLG 311
HAQKA+LA +LG
Sbjct: 293 HAQKALLASILG 304
>gb|AAF17704.1|AF033561_1 (AF033561) ornithine carbamoyltransferase [Canavalia lineata]
Length = 369
Score = 296 bits (749), Expect = 3e-79
Identities = 146/305 (47%), Positives = 208/305 (67%), Gaps = 4/305 (1%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIG-KPHRLLEGKTLAMIFQKPSTRTRVSFEV 66
+D L + D+ + I+ IL+ A +K K G + + +GKT+AM+F KPS RT VSFE
Sbjct: 67 KDFLHINDFDKKSIFKILDRAIEVKALIKSGDRAFQPFKGKTMAMVFCKPSLRTHVSFET 126
Query: 67 AMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPV 126
LGGHA+YL D+Q+ E D AR+LSR+ D IMARV+ H+D+ L+KY SVPV
Sbjct: 127 GFTLLGGHAVYLAPTDIQMGTREETRDVARILSRFTDIIMARVFSHQDILVLSKYGSVPV 186
Query: 127 INGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVVAT 186
+NGL+D++HPCQ +AD +TI E G ++G K+ YVGDGNNV HS + + + V A+
Sbjct: 187 VNGLTDYNHPCQVMADAITIIEHIGKLEGTKIAYVGDGNNVVHSWLEMASLVPIQFVCAS 246
Query: 187 PEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRK 246
P+G+EPD+K ++ A+Q + +DP +AVK AD++YTDVWASMGQ+ EA+ R
Sbjct: 247 PKGFEPDKKTVEKAKQAGL---SKIVITNDPKEAVKGADIVYTDVWASMGQKEEADRRLA 303
Query: 247 IFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVL 306
F+ FQV++ L+ A +FMHCLPA +G EVT+DVI+ P S+++D+AENRLHAQ A++
Sbjct: 304 SFKGFQVDQSLMDLAGSKALFMHCLPAEKGTEVTEDVIEGPRSIIFDQAENRLHAQNAIM 363
Query: 307 ALLLG 311
+LG
Sbjct: 364 LHVLG 368
>pir||E70447 ornithine carbamoyltransferase - Aquifex aeolicus
>gi|2984023|gb|AAC07566.1| (AE000752) ornithine
carbamoyltransferase [Aquifex aeolicus]
Length = 306
Score = 294 bits (744), Expect = 1e-78
Identities = 146/304 (48%), Positives = 211/304 (69%), Gaps = 8/304 (2%)
Query: 8 RDLLCLQDYTPEEIWTILE-TAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEV 66
RD + L D +P+E W I++ T K+ K +++GKP L GKT+A++F KPSTRTRVSFEV
Sbjct: 3 RDFVDLWDLSPKEAWEIVKKTLKVKKGEEELGKP---LSGKTIALLFTKPSTRTRVSFEV 59
Query: 67 AMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPV 126
+ LGG++L+ ++LQ+ RGE + DTAR LS+YVD ++ R + H +++ A +ASVPV
Sbjct: 60 GIYQLGGNSLFFQEKELQVSRGEDVRDTARTLSKYVDGVIVRNHSHTWLKEFANFASVPV 119
Query: 127 INGLSDFSHPCQALADYMTIWEKKG-TIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVVA 185
IN L++ SHPCQ L+D T++E G +K +KV YVGDGNNV ++LM+ G + VA
Sbjct: 120 INALTNMSHPCQILSDVFTLYEHYGEELKNLKVAYVGDGNNVCNTLMVGAGMFGLKLFVA 179
Query: 186 TPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERR 245
TPEGYEP+ K A + + E+GGS EL ++PV++VKDADV+YTDVW SMG+E +
Sbjct: 180 TPEGYEPNSYYYKKALEFSKENGGSVELTNNPVESVKDADVVYTDVWVSMGEE---NKNI 236
Query: 246 KIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAV 305
+ F P+QVN+ L+ AK MHCLPA +G+E+T++V + ++ +AENRLH QK +
Sbjct: 237 EAFLPYQVNEKLLSFAKSSVKVMHCLPAKKGQEITEEVFEKNADFIFTQAENRLHTQKTL 296
Query: 306 LALL 309
+ L
Sbjct: 297 MEFL 300
>sp|O50039|OTC_ARATH ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OTCASE) (ORNITHINE
TRANSCARBAMYLASE) >gi|11257116|pir||T51617 ornithine
carbamoyltransferase (EC 2.1.3.3) [validated] -
Arabidopsis thaliana >gi|2764518|emb|CAA04115.1|
(AJ000476) Ornithine carbamoyltransferase [Arabidopsis
thaliana] >gi|2764737|emb|CAA05510.1| (AJ002524)
ornithine carbamoyltransferase [Arabidopsis thaliana]
Length = 375
Score = 293 bits (743), Expect = 1e-78
Identities = 153/305 (50%), Positives = 208/305 (68%), Gaps = 4/305 (1%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRL-LEGKTLAMIFQKPSTRTRVSFEV 66
+D L + D+ I TIL+ A +K K G+ + L +GK+++MIF KPS RTRVSFE
Sbjct: 73 KDFLAIDDFDTATIKTILDKASEVKALLKSGERNYLPFKGKSMSMIFAKPSMRTRVSFET 132
Query: 67 AMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPV 126
LGGHALYL D+Q+ + E D ARVLSRY D IMARV+ H+D+ DLA Y+SVPV
Sbjct: 133 GFFLLGGHALYLGPNDIQMGKREETPDVARVLSRYNDIIMARVFAHQDILDLANYSSVPV 192
Query: 127 INGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVVAT 186
+NGL+D +HPCQ +AD +T+ + G + KVVYVGDGNN+ HS + + + V A
Sbjct: 193 VNGLTDHNHPCQIMADALTMIKHIGQFERKKVVYVGDGNNMVHSWLELASVIPFHFVCAC 252
Query: 187 PEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRK 246
P+GYEPD++ + A+Q E+ +DP +AV ADV+Y+DVWASMGQ+ EAE RRK
Sbjct: 253 PKGYEPDKERVSKAKQAGL---SKIEITNDPKEAVIGADVVYSDVWASMGQKDEAEARRK 309
Query: 247 IFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVL 306
F+ FQV++ L+K A FMHCLPA RG EVT+ V+++P S+V+ +AENR+HAQ A++
Sbjct: 310 AFQGFQVDEALMKLAGQKAYFMHCLPAERGVEVTNGVVEAPYSIVFPQAENRMHAQYAIM 369
Query: 307 ALLLG 311
LLG
Sbjct: 370 LHLLG 374
>pir||E83203 ornithine carbamoyltransferase, anabolic PA3537 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9949687|gb|AAG06925.1|AE004774_3 (AE004774)
ornithine carbamoyltransferase, anabolic [Pseudomonas
aeruginosa]
Length = 305
Score = 292 bits (739), Expect = 4e-78
Identities = 145/303 (47%), Positives = 199/303 (64%), Gaps = 7/303 (2%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
R L DY+PEE+ ++ LK + G + L+ + L M+F+K STRTR+SFE
Sbjct: 4 RHFLSFMDYSPEELIGLIRRGSELKDLRNRGVLYEPLKSRVLGMVFEKASTRTRLSFEAG 63
Query: 68 MAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVI 127
M LGG A++L+ +D QL RGE I D+ARV+SR +D +M R + H + + A ++ VPVI
Sbjct: 64 MIQLGGQAIFLSPRDTQLGRGEPIGDSARVMSRMLDGVMIRTFAHATLTEFAAHSKVPVI 123
Query: 128 NGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVVATP 187
NGLSD HPCQ LAD T E +G+I+G V ++GDGNN+ +S + A K + VA P
Sbjct: 124 NGLSDDLHPCQLLADMQTFHEHRGSIQGKTVAWIGDGNNMCNSYIEAALKFDFQLRVACP 183
Query: 188 EGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRKI 247
EGYEP + + A +G ++ DP +AV A ++ TDVWASMGQE EA R +
Sbjct: 184 EGYEPKAEFV-------ALAGDRLRVVRDPREAVAGAHLVSTDVWASMGQEDEAAARIAL 236
Query: 248 FRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVLA 307
FRP+QVN L+ A D +FMHCLPAHRGEE++++++D P SV WD+AENRLHAQKA+L
Sbjct: 237 FRPYQVNAALLDGAADDVLFMHCLPAHRGEEISEELLDDPRSVAWDQAENRLHAQKALLE 296
Query: 308 LLL 310
LL+
Sbjct: 297 LLI 299
>sp|O86132|OTCC_BACLI ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC (OTCASE)
>gi|3687417|emb|CAA76778.1| (Y17554) ornithine
carbamoyltransferase [Bacillus licheniformis]
Length = 335
Score = 291 bits (738), Expect = 6e-78
Identities = 157/328 (47%), Positives = 211/328 (63%), Gaps = 19/328 (5%)
Query: 3 VSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRV 62
++LKGR L +D++ EEI +L+ A+ LK + G HR LEGK +A++F+KPSTRTR
Sbjct: 5 INLKGRSYLAEKDFSEEEILYLLDLAQKLKEKKAQGIRHRYLEGKNIALLFEKPSTRTRC 64
Query: 63 SFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYA 122
+F A LG H YL D+QL + E+I DTA+VL R D I R ++H+ V LA+++
Sbjct: 65 AFTTACIDLGAHPEYLGKDDIQLGKKESIEDTAKVLGRMFDGIEFRGFEHEKVISLAEHS 124
Query: 123 SVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLGAD 181
VPV NGL+D HP Q LAD+MT+ E G +KGVK+ Y+GDG NNVA+SL+I G K+G D
Sbjct: 125 GVPVWNGLTDLWHPTQMLADFMTVKEHTGRVKGVKLTYIGDGRNNVANSLLIGGAKVGMD 184
Query: 182 VVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA 241
V + +P+ PD+ ++K AE A ESGG + D KAV ADV+YTDVW SMG+E +
Sbjct: 185 VRICSPQELFPDQDIVKMAEAFAEESGGKITVTSDTDKAVSGADVLYTDVWVSMGEEDKF 244
Query: 242 EERRKIFRPFQVNKDLVKHAKPD-YMFMHCLPAH-----------------RGEEVTDDV 283
ER K+ +P+QVN DLVK D +F+HCLPA + EVTD+V
Sbjct: 245 AERIKLLKPYQVNMDLVKKTGNDNVIFLHCLPAFHDLHTTYGQNVYEQHGLKEMEVTDEV 304
Query: 284 IDSPNSVVWDEAENRLHAQKAVLALLLG 311
S +S V+DEAENR+H KAV+A LG
Sbjct: 305 FRSKHSKVFDEAENRMHTIKAVMAATLG 332
>sp|P11724|OTCA_PSEAE ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (OTCASE)
>gi|279495|pir||OWPSAA ornithine carbamoyltransferase
(EC 2.1.3.3), anabolic - Pseudomonas aeruginosa
>gi|151039|gb|AAA25720.1| (M19939) ornithine
carbamoyltransferase (EC 2.1.3.3) [Pseudomonas
aeruginosa]
Length = 305
Score = 289 bits (731), Expect = 4e-77
Identities = 144/303 (47%), Positives = 198/303 (64%), Gaps = 7/303 (2%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
R L DY+PEE+ ++ LK + G + L+ + L M+F+K STRTR+SFE
Sbjct: 4 RHFLSFMDYSPEELIGLIRRGSELKDLRNRGVLYEPLKSRVLGMVFEKASTRTRLSFEAG 63
Query: 68 MAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVI 127
M LGG A++L+ +D QL RGE I D+ARV+SR +D +M R + H + + A ++ VPVI
Sbjct: 64 MIQLGGQAIFLSPRDTQLGRGEPIGDSARVMSRMLDGVMIRTFAHATLTEFAAHSKVPVI 123
Query: 128 NGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVVATP 187
NGLSD HPCQ LAD T E +G+I+G V ++GDGNN+ +S + K + VA P
Sbjct: 124 NGLSDDLHPCQLLADMQTFHEHRGSIQGKTVAWIGDGNNMCNSYIEEEMKFDFQLRVACP 183
Query: 188 EGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRKI 247
EGYEP + + A +G ++ DP +AV A ++ TDVWASMGQE EA R +
Sbjct: 184 EGYEPKAEFV-------ALAGDRLRVVRDPREAVAGAHLVSTDVWASMGQEDEAAARIAM 236
Query: 248 FRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVLA 307
FRP+QVN L+ A D +FMHCLPAHRGEE++++++D P SV WD+AENRLHAQKA+L
Sbjct: 237 FRPYQVNAALLDGAADDVLFMHCLPAHRGEEISEELLDDPRSVAWDQAENRLHAQKALLE 296
Query: 308 LLL 310
LL+
Sbjct: 297 LLI 299
>gi|6679184 ornithine transcarbamylase [Mus musculus]
>gi|129277|sp|P11725|OTC_MOUSE ORNITHINE
CARBAMOYLTRANSFERASE PRECURSOR (OTCASE) (ORNITHINE
TRANSCARBAMYLASE) >gi|2144398|pir||OWMS ornithine
carbamoyltransferase (EC 2.1.3.3) precursor - mouse
>gi|200163|gb|AAA39865.1| (M17030) ornithine
transcarbamylase [Mus musculus]
Length = 354
Score = 287 bits (728), Expect = 8e-77
Identities = 151/310 (48%), Positives = 208/310 (66%), Gaps = 4/310 (1%)
Query: 3 VSLKGRDLLCLQDYTPEEIWTILETAKMLK--IWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
V LKGRDLL L+++T EEI +L + LK I QK G+ LL+GK+L MIF+K STRT
Sbjct: 35 VQLKGRDLLTLKNFTGEEIQYMLWLSADLKFRIKQK-GEYLPLLQGKSLGMIFEKRSTRT 93
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
R+S E A LGGH +L QD+ L E++ DTARVLS DA++ARVY D++ LAK
Sbjct: 94 RLSTETGFALLGGHPSFLTTQDIHLGVNESLTDTARVLSSMTDAVLARVYKQSDLDTLAK 153
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA 180
AS+P++NGLSD HP Q LADY+T+ E G++KG+ + ++GDGNN+ HS+M++ K G
Sbjct: 154 EASIPIVNGLSDLYHPIQILADYLTLQEHYGSLKGLTLSWIGDGNNILHSIMMSAAKFGM 213
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
+ ATP+GYEPD ++K AEQ A E+G + +DP++A + +V+ TD W SMGQE E
Sbjct: 214 HLQAATPKGYEPDPNIVKLAEQYAKENGTKLSMTNDPLEAARGGNVLITDTWISMGQEDE 273
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
++R + F+ +QV K A D+ F+HCLP + EEV D+V SP S+V+ EAENR
Sbjct: 274 KKKRLQAFQGYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKW 332
Query: 301 AQKAVLALLL 310
AV+ LL
Sbjct: 333 TIMAVMVSLL 342
>sp|Q02095|OTCA_MYCBO ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (OTCASE)
>gi|7433593|pir||S26215 ornithine carbamoyltransferase
(EC 2.1.3.3) - Mycobacterium bovis
>gi|581311|emb|CAA45530.1| (X64203) ornithine
carbamoyltransferase [Mycobacterium bovis]
Length = 307
Score = 286 bits (724), Expect = 2e-76
Identities = 156/305 (51%), Positives = 201/305 (65%), Gaps = 5/305 (1%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEG-KTLAMIFQKPSTRTRVSFEV 66
R L D +P E +LE A LK K R L+G + +A+IF K STRTR SFE+
Sbjct: 3 RHFLRDDDLSPAEQAEVLELAAELK---KDPVSRRPLQGPRGVAVIFDKNSTRTRFSFEL 59
Query: 67 AMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPV 126
+A LGGHA+ +++ QL R ET+ DTA+VLSRYVDAI+ R + + ++ +A A+VPV
Sbjct: 60 GIAQLGGHAVVVDSGSTQLGRDETLQDTAKVLSRYVDAIVWRTFGQERLDAMASVATVPV 119
Query: 127 INGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLGADVVVA 185
IN LSD HPCQ LAD TI E+KG ++G+++ Y GDG NN+AHSL++ G G V VA
Sbjct: 120 INALSDEFHPCQVLADLQTIAERKGALRGLRLSYFGDGANNMAHSLLLGGVTAGIHVTVA 179
Query: 186 TPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERR 245
PEG+ PD V AE+ A ++G S + D A ADV+ TD W SMGQE + +R
Sbjct: 180 APEGFLPDPSVRAAAERRAQDTGASVTVTADAHAAAAAADVLVTDTWTSMGQENDGLDRV 239
Query: 246 KIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAV 305
K FRPFQ+N L+ A D + +HCLPAHRG+E+TD V+D P S VWDEAENRLHAQKAV
Sbjct: 240 KPFRPFQLNSRLLALADSDAIVLHCLPAHRGDEITDAVMDGPASAVWDEAENRLHAQKAV 299
Query: 306 LALLL 310
L LL
Sbjct: 300 LVWLL 304
>sp|O19072|OTC_PIG ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OTCASE) (ORNITHINE
TRANSCARBAMYLASE) >gi|2293083|emb|CAA73480.1| (Y13045)
ornithine transcarbamylase [Sus scrofa]
Length = 328
Score = 286 bits (723), Expect = 3e-76
Identities = 153/310 (49%), Positives = 208/310 (66%), Gaps = 4/310 (1%)
Query: 3 VSLKGRDLLCLQDYTPEEIWTILETAKMLK--IWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
V LKGRDLL L+++T EEI IL + LK I QK G+ LL+GK+L MIF+K STRT
Sbjct: 9 VQLKGRDLLTLKNFTGEEIKYILWLSADLKFRIKQK-GEYLPLLQGKSLGMIFEKRSTRT 67
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
R+S E A LGGH +L QD+ L E++ DTARVLS DA++ARVY D++ LA+
Sbjct: 68 RLSTETGFALLGGHPCFLTTQDIHLGVNESLKDTARVLSSMTDAVLARVYKQSDLDILAQ 127
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA 180
AS+P+INGLSD HP Q LADY+T+ E G +KG+ + ++GDGNN+ HS+M++ K G
Sbjct: 128 EASIPIINGLSDLYHPIQILADYLTLQEHYGALKGLTLSWIGDGNNILHSIMMSAAKFGM 187
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
+ VATP+GYEPD + K AEQ A E+G + L +DP++A + +V+ TD W SMGQE E
Sbjct: 188 HLQVATPKGYEPDPSITKLAEQYAKENGTNVSLTNDPLEAARGGNVLITDTWISMGQEEE 247
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
++R + F+ +QV + A D+ F+HCLP + EEV D+V SP S+V+ EAENR
Sbjct: 248 KKKRLQAFQGYQVTMKTAEVAASDWTFLHCLP-RKPEEVDDEVFYSPQSLVFPEAENRKW 306
Query: 301 AQKAVLALLL 310
AV+ LL
Sbjct: 307 TIMAVMVSLL 316
>gb|AAF61405.1|AF134841_1 (AF134841) ornithine transcarbamylase [Bos taurus]
Length = 354
Score = 286 bits (723), Expect = 3e-76
Identities = 153/310 (49%), Positives = 206/310 (66%), Gaps = 4/310 (1%)
Query: 3 VSLKGRDLLCLQDYTPEEIWTILETAKMLK--IWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
V LKGRDLL L+++T EEI +L + LK I QK G+ LL+GK+L MIF+K STRT
Sbjct: 35 VQLKGRDLLTLKNFTGEEIKYMLWLSADLKFRIKQK-GEYLPLLQGKSLGMIFEKRSTRT 93
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
R+S E A LGGH +L D+ L E++ DTARVLS DA++ARVY D++ LAK
Sbjct: 94 RLSTETGFALLGGHPCFLTTDDIHLGVNESLTDTARVLSSMTDAVLARVYKQSDLDLLAK 153
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA 180
AS+P++NGLSD HP Q LADY+T+ E G++KG+ + ++GDGNN+ HS+M++ K G
Sbjct: 154 EASIPIVNGLSDLYHPIQILADYLTLQEHYGSLKGLTLSWIGDGNNILHSIMMSAAKFGM 213
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
+ VATP+GYEPD + K AEQ A E+G L +DP++A +V+ TD W SMGQE E
Sbjct: 214 HLQVATPKGYEPDPSITKMAEQYAKENGTKLSLTNDPLEAACGGNVLITDTWISMGQEEE 273
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
++R + F+ +QV K A PD+ F+HCLP + EEV D+V SP S+V EAENR
Sbjct: 274 KKKRLQAFQGYQVTMKTAKVAAPDWTFLHCLP-RKPEEVDDEVFYSPRSLVSPEAENRKW 332
Query: 301 AQKAVLALLL 310
AV+ LL
Sbjct: 333 TIMAVMVSLL 342
>sp|P94991|OTCA_MYCTU ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (OTCASE)
>gi|7433592|pir||C70621 probable argF protein -
Mycobacterium tuberculosis (strain H37RV)
>gi|1839008|emb|CAB06650.1| (Z85982) argF [Mycobacterium
tuberculosis]
Length = 307
Score = 285 bits (722), Expect = 4e-76
Identities = 155/305 (50%), Positives = 201/305 (65%), Gaps = 5/305 (1%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEG-KTLAMIFQKPSTRTRVSFEV 66
R L D +P E +LE A LK K R L+G + +A+IF K STRTR SFE+
Sbjct: 3 RHFLRDDDLSPAEQAEVLELAAELK---KDPVSRRPLQGPRGVAVIFDKNSTRTRFSFEL 59
Query: 67 AMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPV 126
+A LGGHA+ +++ QL R ET+ DTA+VLSRYVDAI+ R + + ++ +A A+VPV
Sbjct: 60 GIAQLGGHAVVVDSGSTQLGRDETLQDTAKVLSRYVDAIVWRTFGQERLDAMASVATVPV 119
Query: 127 INGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLGADVVVA 185
IN LSD HPCQ LAD TI E+KG ++G+++ Y GDG NN+AHSL++ G G V VA
Sbjct: 120 INALSDEFHPCQVLADLQTIAERKGALRGLRLSYFGDGANNMAHSLLLGGVTAGIHVTVA 179
Query: 186 TPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERR 245
PEG+ PD V AE+ A ++G S + D A ADV+ TD W SMGQE + +R
Sbjct: 180 APEGFLPDPSVRAAAERRAQDTGASVTVTADAHAAAAGADVLVTDTWTSMGQENDGLDRV 239
Query: 246 KIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAV 305
K FRPFQ+N L+ A D + +HCLPAHRG+E+TD V+D P S VWDEAENRLHAQKA+
Sbjct: 240 KPFRPFQLNSRLLALADSDAIVLHCLPAHRGDEITDAVMDGPASAVWDEAENRLHAQKAL 299
Query: 306 LALLL 310
L LL
Sbjct: 300 LVWLL 304
>gi|6981312 ornithine carbamoyltransferase [Rattus norvegicus]
>gi|129279|sp|P00481|OTC_RAT ORNITHINE
CARBAMOYLTRANSFERASE PRECURSOR (OTCASE) (ORNITHINE
TRANSCARBAMYLASE) >gi|66490|pir||OWRT ornithine
carbamoyltransferase (EC 2.1.3.3) precursor - rat
>gi|205872|gb|AAA41767.1| (M11266) preornithine
transcarbamylase [Rattus norvegicus]
>gi|205874|gb|AAA41768.1| (K03040) preornithine
carbamoyltransferase EC 2.1.3.3 [Rattus norvegicus]
>gi|205886|gb|AAA41769.1| (M16933) ornithine
carbamoyltransferase [Rattus norvegicus]
Length = 354
Score = 285 bits (722), Expect = 4e-76
Identities = 150/310 (48%), Positives = 208/310 (66%), Gaps = 4/310 (1%)
Query: 3 VSLKGRDLLCLQDYTPEEIWTILETAKMLK--IWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
V LKGRDLL L+++T EEI +L + LK I QK G+ LL+GK+L MIF+K STRT
Sbjct: 35 VQLKGRDLLTLKNFTGEEIQYMLWLSADLKFRIKQK-GEYLPLLQGKSLGMIFEKRSTRT 93
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
R+S E A LGGH +L QD+ L E++ DTARVLS DA++ARVY D++ LAK
Sbjct: 94 RLSTETGFALLGGHPSFLTTQDIHLGVNESLTDTARVLSSMTDAVLARVYKQSDLDILAK 153
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA 180
A++P++NGLSD HP Q LADY+T+ E G++KG+ + ++GDGNN+ HS+M++ K G
Sbjct: 154 EATIPIVNGLSDLYHPIQILADYLTLQEHYGSLKGLTLSWIGDGNNILHSIMMSAAKFGM 213
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
+ ATP+GYEPD ++K AEQ A E+G + +DP++A + +V+ TD W SMGQE E
Sbjct: 214 HLQAATPKGYEPDPNIVKLAEQYAKENGTRLSMTNDPLEAARGGNVLITDTWISMGQEDE 273
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
++R + F+ +QV K A D+ F+HCLP + EEV D+V SP S+V+ EAENR
Sbjct: 274 KKKRLQAFQGYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKW 332
Query: 301 AQKAVLALLL 310
AV+ LL
Sbjct: 333 TIMAVMVSLL 342
>sp|P96108|OTCA_THEMA ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (OTCASE)
>gi|7433604|pir||C72294 ornithine carbamoyltransferase,
anabolic - Thermotoga maritima (strain MSB8)
>gi|1806543|emb|CAA71670.1| (Y10661) ornithine
carbamoyltransferase [Thermotoga maritima]
>gi|4981642|gb|AAD36173.1|AE001769_3 (AE001769)
ornithine carbamoyltransferase, anabolic [Thermotoga
maritima]
Length = 313
Score = 285 bits (722), Expect = 4e-76
Identities = 155/312 (49%), Positives = 208/312 (65%), Gaps = 2/312 (0%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
M V+LKGR LL L D++PEEI +L+ +K +K+ + +G TLAMIF+K STRT
Sbjct: 1 MSVNLKGRSLLTLLDFSPEEIRYLLDISKQVKMENRSKLRTERFKGMTLAMIFEKRSTRT 60
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
R++FE A A GGH ++L+ D+ L E++ DTARVL R VDAIM R Y + VE LA+
Sbjct: 61 RLAFETAFAEEGGHPIFLSPNDIHLGAKESLEDTARVLGRMVDAIMFRGYKQETVEKLAE 120
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD-GNNVAHSLMIAGTKLG 179
Y+ VPV NGL+D HP QALAD MTI E G +KGVKVV++GD NNVA SLMIA K+G
Sbjct: 121 YSGVPVYNGLTDEFHPTQALADLMTIEENFGRLKGVKVVFMGDTRNNVATSLMIACAKMG 180
Query: 180 ADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEA 239
+ V PE +P V K ++ E+ GS + +A+ ADV+YTDVWASMG+E
Sbjct: 181 MNFVACGPEELKPRSDVFKRCQEIVKETDGSVSFTSNLEEALAGADVVYTDVWASMGEED 240
Query: 240 EAEERRKIFRPFQVNKDLVK-HAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENR 298
+ +ER + +P+QVN+ +++ K + +FMHCLPA +G+EVT +VI+ S VWDEAENR
Sbjct: 241 KEKERMALLKPYQVNERVMEMTGKSETIFMHCLPAVKGQEVTYEVIEGKQSRVWDEAENR 300
Query: 299 LHAQKAVLALLL 310
H KAV+ L
Sbjct: 301 KHTIKAVMIATL 312
>emb|CAA30121.1| (X07092) ornithine transcarbamylase [Mus musculus]
Length = 354
Score = 284 bits (720), Expect = 7e-76
Identities = 150/310 (48%), Positives = 207/310 (66%), Gaps = 4/310 (1%)
Query: 3 VSLKGRDLLCLQDYTPEEIWTILETAKMLK--IWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
V LKGRDLL L+++T EEI +L + LK I QK G+ LL+GK+L MIF+K STRT
Sbjct: 35 VQLKGRDLLTLKNFTGEEIQYMLWLSADLKFRIKQK-GEYLPLLQGKSLGMIFEKRSTRT 93
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
R+S E A LGGH +L QD+ L E++ DTARVLS DA++ARVY D++ LAK
Sbjct: 94 RLSTETGFALLGGHPSFLTTQDIHLGVNESLTDTARVLSSMTDAVLARVYKQSDLDTLAK 153
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA 180
AS+P++NGLSD HP Q LADY+T+ E G++KG+ + ++ DGNN+ HS+M++ K G
Sbjct: 154 EASIPIVNGLSDLYHPIQILADYLTLQEHYGSLKGLTLSWIRDGNNILHSIMMSAAKFGM 213
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
+ ATP+GYEPD ++K AEQ A E+G + +DP++A + +V+ TD W SMGQE E
Sbjct: 214 HLQAATPKGYEPDPNIVKLAEQYAKENGTKLSMTNDPLEAARGGNVLITDTWISMGQEDE 273
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
++R + F+ +QV K A D+ F+HCLP + EEV D+V SP S+V+ EAENR
Sbjct: 274 KKKRLQAFQGYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKW 332
Query: 301 AQKAVLALLL 310
AV+ LL
Sbjct: 333 TIMAVMVSLL 342
>sp|P00480|OTC_HUMAN ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OTCASE) (ORNITHINE
TRANSCARBAMYLASE) >gi|279486|pir||OWHU ornithine
carbamoyltransferase (EC 2.1.3.3) precursor - human
>gi|219959|dbj|BAA00161.1| (D00230) ornithine
transcarbamylase [Homo sapiens]
Length = 354
Score = 284 bits (719), Expect = 9e-76
Identities = 153/310 (49%), Positives = 206/310 (66%), Gaps = 4/310 (1%)
Query: 3 VSLKGRDLLCLQDYTPEEIWTILETAKMLK--IWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
V LKGRDLL L+++T EEI +L + LK I QK G+ LL+GK+L MIF+K STRT
Sbjct: 35 VQLKGRDLLTLKNFTGEEIKYMLWLSADLKFRIKQK-GEYLPLLQGKSLGMIFEKRSTRT 93
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
R+S E +A LGGH +L QD+ L E++ DTARVLS DA++ARVY D++ LAK
Sbjct: 94 RLSTETGLALLGGHPCFLTTQDIHLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAK 153
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA 180
AS+P+INGLSD HP Q LADY+T+ E ++KG+ + ++GDGNN+ HS+M++ K G
Sbjct: 154 EASIPIINGLSDLYHPIQILADYLTLQEHYSSLKGLTLSWIGDGNNILHSIMMSAAKFGM 213
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
+ ATP+GYEPD V K AEQ A E+G L +DP++A +V+ TD W SMGQE E
Sbjct: 214 HLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEE 273
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
++R + F+ +QV K A D+ F+HCLP + EEV D+V SP S+V+ EAENR
Sbjct: 274 KKKRLQAFQGYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKW 332
Query: 301 AQKAVLALLL 310
AV+ LL
Sbjct: 333 TIMAVMVSLL 342
>prf||1403355A Orn transcarbamylase [Homo sapiens]
Length = 354
Score = 284 bits (719), Expect = 9e-76
Identities = 153/310 (49%), Positives = 206/310 (66%), Gaps = 4/310 (1%)
Query: 3 VSLKGRDLLCLQDYTPEEIWTILETAKMLK--IWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
V LKGRDLL L+++T EEI +L + LK I QK G+ LL+GK+L MIF+K STRT
Sbjct: 35 VQLKGRDLLTLRNFTGEEIKYMLWLSADLKFRIKQK-GEYLPLLQGKSLGMIFEKRSTRT 93
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
R+S E +A LGGH +L QD+ L E++ DTARVLS DA++ARVY D++ LAK
Sbjct: 94 RLSTETGLALLGGHPCFLTTQDIHLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAK 153
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA 180
AS+P+INGLSD HP Q LADY+T+ E ++KG+ + ++GDGNN+ HS+M++ K G
Sbjct: 154 EASIPIINGLSDLYHPIQILADYLTLQEHYSSLKGLTLSWIGDGNNILHSIMMSAAKFGM 213
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
+ ATP+GYEPD V K AEQ A E+G L +DP++A +V+ TD W SMGQE E
Sbjct: 214 HLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEE 273
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
++R + F+ +QV K A D+ F+HCLP + EEV D+V SP S+V+ EAENR
Sbjct: 274 KKKRLQAFQGYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKW 332
Query: 301 AQKAVLALLL 310
AV+ LL
Sbjct: 333 TIMAVMVSLL 342
>emb|CAA26007.1| (X01976) OTCase precursor [Rattus norvegicus]
Length = 354
Score = 283 bits (716), Expect = 2e-75
Identities = 149/310 (48%), Positives = 207/310 (66%), Gaps = 4/310 (1%)
Query: 3 VSLKGRDLLCLQDYTPEEIWTILETAKMLK--IWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
V LKGRDLL L+++T EEI +L + LK I QK G+ LL+GK+L MIF+K STRT
Sbjct: 35 VQLKGRDLLTLKNFTGEEIQYMLWLSADLKFRIKQK-GEYLPLLQGKSLGMIFEKRSTRT 93
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
R+S E A LGGH +L QD+ L E++ DTARVLS DA++ARVY D++ LAK
Sbjct: 94 RLSTETGFALLGGHPSFLTTQDIHLGVNESLTDTARVLSSMTDAVLARVYKQSDLDILAK 153
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA 180
A++P++NGLSD HP Q LADY+T+ E G++KG+ + ++GDGNN+ HS+M++ K G
Sbjct: 154 EATIPIVNGLSDLYHPIQILADYLTLQEHYGSLKGLTLSWIGDGNNILHSIMMSAAKFGM 213
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
+ ATP+GYEPD ++K AEQ A E+ + +DP++A + +V+ TD W SMGQE E
Sbjct: 214 HLQAATPKGYEPDPNIVKLAEQYAKENSTRLSMTNDPLEAARGGNVLITDTWISMGQEDE 273
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
++R + F+ +QV K A D+ F+HCLP + EEV D+V SP S+V+ EAENR
Sbjct: 274 KKKRLQAFQGYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKW 332
Query: 301 AQKAVLALLL 310
AV+ LL
Sbjct: 333 TIMAVMVSLL 342
>pir||JE0309 ornithine carbamoyltransferase (EC 2.1.3.3) - chicken
>gi|4218929|gb|AAD12234.1| (AF065629) ornithine
transcarbamylase precursor [Gallus gallus]
>gi|4927368|gb|AAD33083.1| (AF065638) ornithine
transcarbamylase [Gallus gallus]
Length = 354
Score = 282 bits (715), Expect = 3e-75
Identities = 151/313 (48%), Positives = 206/313 (65%), Gaps = 6/313 (1%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKI---GKPHRLLEGKTLAMIFQKPS 57
M V LKGRDLL LQ+YT +E+ +L A LK Q+I G+ L++GK+LAMIF+K S
Sbjct: 33 MNVCLKGRDLLTLQNYTADELKYLLWVASDLK--QRIKDKGEYLPLMQGKSLAMIFEKRS 90
Query: 58 TRTRVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVED 117
TRTR+S E A LGGH+ +L QD+ L E++ DTARVLS +AI+ARVY H D++
Sbjct: 91 TRTRLSAETGFALLGGHSSFLTKQDIHLGTNESLTDTARVLSSMTNAILARVYKHNDLDL 150
Query: 118 LAKYASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTK 177
+ K A++PVINGLSD HP Q LADY+T+ E G + G+ + ++GDGNNV HS+M + K
Sbjct: 151 MTKEATIPVINGLSDLYHPLQILADYLTLQEHYGGLNGLTIAWIGDGNNVLHSIMTSAAK 210
Query: 178 LGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQ 237
LG + +ATP+G+EPD ++ K EQ + E G L DP++A A+V+ TD W SMGQ
Sbjct: 211 LGMHLRIATPKGFEPDLRITKVTEQYSKEYGTRLLLTTDPLEAANGANVLVTDTWISMGQ 270
Query: 238 EAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAEN 297
E E R K F+ +Q+ V+ A ++ F+HCLP + EEV D+V SP S+V+ EAEN
Sbjct: 271 EEEKRRRLKAFQGYQITMQTVQSAASNWTFLHCLP-RKPEEVDDEVFYSPRSLVFQEAEN 329
Query: 298 RLHAQKAVLALLL 310
R AV+ LL
Sbjct: 330 RKWTIMAVMVSLL 342
>pdb|1C9Y|A Chain A, Human Ornithine Transcarbamylase: Crystallographic
Insights Into Substrate Recognition And Catalytic
Mechanism >gi|6137343|pdb|1OTH|A Chain A, Crystal
Structure Of Human Ornithine Transcarbamoylase Complexed
With N-Phosphonacetyl-L-Ornithine
Length = 321
Score = 282 bits (713), Expect = 5e-75
Identities = 152/310 (49%), Positives = 205/310 (66%), Gaps = 4/310 (1%)
Query: 3 VSLKGRDLLCLQDYTPEEIWTILETAKMLK--IWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
V LKGRDLL L+++T EEI +L + LK I QK G+ LL+GK+L MIF+K STRT
Sbjct: 2 VQLKGRDLLTLKNFTGEEIKYMLWLSADLKFRIKQK-GEYLPLLQGKSLGMIFEKRSTRT 60
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
R+S E A LGGH +L QD+ L E++ DTARVLS DA++ARVY D++ LAK
Sbjct: 61 RLSTETGFALLGGHPCFLTTQDIHLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAK 120
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA 180
AS+P+INGLSD HP Q LADY+T+ E ++KG+ + ++GDGNN+ HS+M++ K G
Sbjct: 121 EASIPIINGLSDLYHPIQILADYLTLQEHYSSLKGLTLSWIGDGNNILHSIMMSAAKFGM 180
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
+ ATP+GYEPD V K AEQ A E+G L +DP++A +V+ TD W SMG+E E
Sbjct: 181 HLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGREEE 240
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
++R + F+ +QV K A D+ F+HCLP + EEV D+V SP S+V+ EAENR
Sbjct: 241 KKKRLQAFQGYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKW 299
Query: 301 AQKAVLALLL 310
AV+ LL
Sbjct: 300 TIMAVMVSLL 309
>gb|AAF61410.1|AF134846_1 (AF134846) ornithine transcarbamylase [Trachemys scripta elegans]
Length = 354
Score = 281 bits (712), Expect = 6e-75
Identities = 151/311 (48%), Positives = 205/311 (65%), Gaps = 6/311 (1%)
Query: 3 VSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKI---GKPHRLLEGKTLAMIFQKPSTR 59
++LKGRDLL LQ+YT EEI +L TA LK Q+I G+ LL+GK+LAMIF+K STR
Sbjct: 35 INLKGRDLLTLQNYTAEEIKYLLWTASDLK--QRIKDKGEYLPLLQGKSLAMIFEKRSTR 92
Query: 60 TRVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLA 119
TR+S E A LGGH +L QD+ L E++ DTARVLS +A++ARVY D++ LA
Sbjct: 93 TRLSTETGFALLGGHPCFLTTQDIHLGVNESLTDTARVLSSMTNAVLARVYKQSDLDLLA 152
Query: 120 KYASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLG 179
K AS+P++NGLSD HP Q LADY+T+ E G +KG+ + ++GDGNNV +S++++ K G
Sbjct: 153 KEASIPIVNGLSDSYHPIQILADYLTLQEHYGYLKGLTISWIGDGNNVLNSILMSAAKFG 212
Query: 180 ADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEA 239
+ VATP+G+EPD V+K AE+ + E DP++A A+V+ TD W SMGQE
Sbjct: 213 MHLRVATPKGFEPDPNVVKVAEEYSKEYSTKLFFTTDPLEAASGANVLVTDTWISMGQEE 272
Query: 240 EAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRL 299
E E K F+ +Q+ KHA D+ F+HCLP + EEV D+V P S+V+ EAENR
Sbjct: 273 EKESDLKAFQGYQITMQTGKHAASDWTFLHCLP-RKPEEVDDEVFYFPRSLVFQEAENRK 331
Query: 300 HAQKAVLALLL 310
AV+ LL
Sbjct: 332 WTIMAVMVSLL 342
>sp|Q48296|OTC_HALSA ORNITHINE CARBAMOYLTRANSFERASE (OTCASE) >gi|1084274|pir||S49261
ornithine carbamoyltransferase (EC 2.1.3.3) [validated]
- Halobacterium salinarum >gi|550341|emb|CAA57356.1|
(X81712) ornithine carbamoyltransferase [Halobacterium
halobium] >gi|984742|emb|CAA56906.1| (X80931) ornithine
transcarbamoylase [Halobacterium salinarum]
>gi|10584351|gb|AAG20946.1| (AE005161) ornithine
carbamoyltransferase; ArcB [Halobacterium sp. NRC-1]
Length = 295
Score = 280 bits (710), Expect = 1e-74
Identities = 143/301 (47%), Positives = 202/301 (66%), Gaps = 11/301 (3%)
Query: 10 LLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAMA 69
L+ + D EEI +L+ A +K + G+ +++ K+L M+F KPSTRTR+SFE M
Sbjct: 4 LVDINDVESEEIEQLLDLAASMK--ENPGEFSGVMDNKSLVMLFAKPSTRTRLSFETGMT 61
Query: 70 HLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVING 129
LGGH ++ QL RGE I+D ++V+SRY DAIMAR+++H ++ +LA+ A VPV+NG
Sbjct: 62 QLGGHGIFFEMGSSQLSRGEPISDVSQVMSRYEDAIMARLFEHDEMMELAENADVPVVNG 121
Query: 130 LSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVVATPEG 189
L+DF HPCQAL D T+ EK + + +VGDGNNVAHSLM A K+G D +ATPEG
Sbjct: 122 LTDFLHPCQALTDMFTMQEKD---RLDTLAFVGDGNNVAHSLMQASAKMGVDCRIATPEG 178
Query: 190 YEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRKIFR 249
EPDE++ S + + +DP +AV A +Y DV+ SMG+E + EE+ F
Sbjct: 179 MEPDEEI------QDRVSDANVTVTNDPYEAVDGATAVYGDVFVSMGEEEQREEKLAEFD 232
Query: 250 PFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVLALL 309
FQ+++DL+ A+ D +FMHCLPAHRGEEVT +V D P SV++D+AENR+H QKA++ L
Sbjct: 233 GFQIDQDLMDAARDDAIFMHCLPAHRGEEVTAEVADGPQSVIFDQAENRMHVQKAIVHTL 292
Query: 310 L 310
+
Sbjct: 293 V 293
>sp|Q02047|OTCA_PSESH ORNITHINE CARBAMOYLTRANSFERASE, PHASEOLOTOXIN-SENSITIVE, ANABOLIC
(OTCASE) >gi|540984|pir||S41291 ornithine
carbamoyltransferase (EC 2.1.3.3) - Pseudomonas syringae
>gi|151405|gb|AAA25909.1| (M99382) phaseolotoxin
sensitive octase [Pseudomonas syringae]
>gi|440574|emb|CAA54264.1| (X76945) orthinine
carbamoyltransferase [Pseudomonas syringae]
Length = 306
Score = 280 bits (710), Expect = 1e-74
Identities = 142/306 (46%), Positives = 196/306 (63%), Gaps = 7/306 (2%)
Query: 5 LKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSF 64
+ R L + DYTP+E+ ++ LK + G+ L+ + L MIF+K STRTR+SF
Sbjct: 1 MNARHFLSMMDYTPDELLGLIRRGVELKDLRIRGELFEPLKNRVLGMIFEKSSTRTRLSF 60
Query: 65 EVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASV 124
E M LGG A++L+ +D QL RGE IAD+A+V+SR +DA+M R Y H ++ + A + V
Sbjct: 61 EAGMIQLGGQAIFLSHRDTQLGRGEPIADSAKVMSRMLDAVMIRTYAHSNLTEFAANSRV 120
Query: 125 PVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVV 184
PVINGLSD HPCQ LAD T E +G+IKG V ++GDGNN+ +S + A + + V
Sbjct: 121 PVINGLSDDLHPCQLLADMQTFLEHRGSIKGKTVAWIGDGNNMCNSYIEAAIQFDFQLRV 180
Query: 185 ATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEER 244
A P GYEP+ + + A +G ++ DP AV A ++ TDVW SMGQE E R
Sbjct: 181 ACPAGYEPNPEFL-------ALAGERVTIVRDPKAAVAGAHLVSTDVWTSMGQEEETARR 233
Query: 245 RKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKA 304
+F PFQV + + A+ D +FMHCLPAHRGEE++ D++D SV WD+AENRLHAQKA
Sbjct: 234 MALFAPFQVTRASLDLAEKDVLFMHCLPAHRGEEISVDLLDDSRSVAWDQAENRLHAQKA 293
Query: 305 VLALLL 310
+L L+
Sbjct: 294 LLEFLV 299
>gb|AAA41772.1| (K00001) preornithine carbamoyl transferase [Rattus norvegicus]
Length = 354
Score = 280 bits (708), Expect = 2e-74
Identities = 148/310 (47%), Positives = 206/310 (65%), Gaps = 4/310 (1%)
Query: 3 VSLKGRDLLCLQDYTPEEIWTILETAKMLK--IWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
V LK RDLL L+++T EEI +L + LK I QK G+ LL+GK+L MIF+K STRT
Sbjct: 35 VQLKPRDLLTLKNFTGEEIQYMLWLSADLKFRIKQK-GEYLPLLQGKSLGMIFEKRSTRT 93
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
R+S E A LGGH +L QD+ L E++ DTARVLS DA++ARVY D++ LAK
Sbjct: 94 RLSTETGFALLGGHPSFLTTQDIHLGVNESLTDTARVLSSMTDAVLARVYKQSDLDILAK 153
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA 180
A++P++NGLSD HP Q LADY+T+ E G++KG+ + ++GDGNN+ HS+M++ K G
Sbjct: 154 EATIPIVNGLSDLYHPIQILADYLTLQEHYGSLKGLTLSWIGDGNNILHSIMMSAAKFGM 213
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
+ ATP+GYEPD ++K AEQ A E+ + +DP++A + +V+ TD W SMGQE E
Sbjct: 214 HLQAATPKGYEPDPNIVKLAEQYAKENSTRLSMTNDPLEAARGGNVLITDTWISMGQEDE 273
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
++R + F+ +QV K A D+ F+HCLP + EEV D+V SP S+V+ EAENR
Sbjct: 274 KKKRLQAFQGYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKW 332
Query: 301 AQKAVLALLL 310
AV+ LL
Sbjct: 333 TIMAVMVSLL 342
>gb|AAF61409.1|AF134845_1 (AF134845) ornithine transcarbamylase [Alligator mississippiensis]
Length = 357
Score = 279 bits (705), Expect = 4e-74
Identities = 154/311 (49%), Positives = 204/311 (65%), Gaps = 6/311 (1%)
Query: 3 VSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKI---GKPHRLLEGKTLAMIFQKPSTR 59
V LKGRDLL LQ+YT EEI +L A LK Q+I G+ L++GK+LAMIF+K STR
Sbjct: 38 VHLKGRDLLTLQNYTAEEIKYLLWVASDLK--QRIKHKGEYLPLMQGKSLAMIFEKRSTR 95
Query: 60 TRVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLA 119
TR+S E A LGGH +L QD+ L E++ DTARVLS DAI+ARVY D++ LA
Sbjct: 96 TRLSTETGFAVLGGHPCFLTTQDIHLGINESLTDTARVLSGMTDAILARVYKQSDLDLLA 155
Query: 120 KYASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLG 179
K AS+P+INGLSD HP Q +ADY+T+ E G + G+ + ++GDGNNV +S+M++ KLG
Sbjct: 156 KEASIPIINGLSDSYHPIQIVADYLTLQEHYGHLNGLTISWIGDGNNVLNSIMMSAAKLG 215
Query: 180 ADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEA 239
+ VATP+ +EPD ++IK AEQ + E G L DP++A A+V+ TD W SMGQE
Sbjct: 216 MHLHVATPKSFEPDYRIIKIAEQYSKEYGTKLLLTTDPLEAASGANVLVTDTWISMGQEQ 275
Query: 240 EAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRL 299
E ER + F+ +Q+ K A D+ F+HCLP + EEV D V S S+V+ EAENR
Sbjct: 276 EKIERLRAFQGYQITMQTAKAAASDWTFLHCLP-RKPEEVDDRVFYSSRSLVFQEAENRK 334
Query: 300 HAQKAVLALLL 310
AV+ LL
Sbjct: 335 WTIMAVMVSLL 345
>sp|P96134|OTCA_THETH ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (OTCASE) (OTC)
>gi|1781357|emb|CAA71315.1| (Y10266) ornithine
carbamoyltransferase [Thermus thermophilus]
>gi|3859094|emb|CAA77140.1| (Y18353) ornithine
carbamoyltransferase [Thermus thermophilus]
Length = 301
Score = 278 bits (704), Expect = 5e-74
Identities = 147/303 (48%), Positives = 202/303 (66%), Gaps = 12/303 (3%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
+DLL Y P+E+ +L+ A+ LK + G+ L+GK LA++F+KPS RTR + EVA
Sbjct: 10 KDLLDFSGYGPKELQALLDLAERLKRERYRGED---LKGKVLALLFEKPSLRTRTTLEVA 66
Query: 68 MAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVI 127
M HLGGHA+YL+ + + + E + D A+ L R+V+ I ARV+ H+ VE LA++A VPV+
Sbjct: 67 MVHLGGHAVYLDQKQVGIGEREPVRDVAKNLERFVEGIAARVFRHETVEALARHAKVPVV 126
Query: 128 NGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVVATP 187
N LSD +HP QALAD +T+ E G + G++V +VGDGNNV +SL+ G V VATP
Sbjct: 127 NALSDRAHPLQALADLLTLKEVFGGLAGLEVAWVGDGNNVLNSLLEVAPLAGLKVRVATP 186
Query: 188 EGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRKI 247
+GYEPD ++K A NA HDP +A A +YTDVW SMGQEAE +R +
Sbjct: 187 KGYEPDPGLLKRA--NAF-------FTHDPKEAALGAHALYTDVWTSMGQEAERAKRLRD 237
Query: 248 FRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVLA 307
F+ FQVN +L+K +P+ +F+HCLPAH GEE T++ + P S V+D+AENRLH KAVL
Sbjct: 238 FQGFQVNGELLKLLRPEGVFLHCLPAHYGEETTEEAVHGPRSRVFDQAENRLHTAKAVLL 297
Query: 308 LLL 310
LL
Sbjct: 298 TLL 300
>gi|9257234 ornithine carbamoyltransferase precursor; Ornithine
transcarbamylase [Homo sapiens]
>gi|189407|gb|AAA59975.1| (K02100) ornithine
transcarbamylase [Homo sapiens]
Length = 354
Score = 276 bits (698), Expect = 3e-73
Identities = 151/310 (48%), Positives = 202/310 (64%), Gaps = 4/310 (1%)
Query: 3 VSLKGRDLLCLQDYTPEEIWTILETAKMLK--IWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
V LKGRDLL L+++T EEI +L + LK I QK G+ LL+GK+L MIF+K STRT
Sbjct: 35 VQLKGRDLLTLKNFTGEEIKYMLWLSADLKFRIKQK-GEYLPLLQGKSLGMIFEKRSTRT 93
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
R+S E A LGGH + QD+ L E++ DTARVLS DA++ARVY D++ LAK
Sbjct: 94 RLSTETGFALLGGHPCFPTTQDIHLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAK 153
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA 180
AS+P+INGLSD HP Q LADY+T+ E ++KG+ + GDGNN+ HS+M++ K G
Sbjct: 154 EASIPIINGLSDLYHPIQILADYLTLQEHYSSLKGLTLSCFGDGNNILHSIMMSAAKFGM 213
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
+ ATP+GYEPD V K AEQ A E+G L +DP++A +V+ TD W SMG+E E
Sbjct: 214 HLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGREEE 273
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
++R + F+ +QV K A D+ F+HCLP + EEV D+V SP S+V+ EAENR
Sbjct: 274 KKKRLQAFQGYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKW 332
Query: 301 AQKAVLALLL 310
AV+ LL
Sbjct: 333 TIMAVMVSLL 342
>pir||F75562 ornithine carbamoyltransferase - Deinococcus radiodurans (strain
R1) >gi|6457745|gb|AAF09673.1|AE001871_5 (AE001871)
ornithine carbamoyltransferase [Deinococcus radiodurans]
Length = 353
Score = 276 bits (698), Expect = 3e-73
Identities = 148/313 (47%), Positives = 209/313 (66%), Gaps = 12/313 (3%)
Query: 5 LKGRDLLCLQDYTPEEIWTILETAKMLKI--WQKIGKPHRLLEGKTLAMIFQKPSTRTRV 62
L GRD L D T E+ +++TA +K W+ + KP L G +LA++F+K S RTR
Sbjct: 47 LAGRDFLSNLDMTSAELRAVMDTAHSMKAGEWRAV-KP---LSGLSLALVFEKASLRTRT 102
Query: 63 SFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYA 122
+F+V M LGGHA+ L+ ++ L E ++D AR L R+VD +M RVY + + +LA++A
Sbjct: 103 TFDVGMYQLGGHAITLSNTEIGLGTRERVSDVARNLERWVDGVMGRVYLQQTLVELAQHA 162
Query: 123 SVPVINGLSDFSHPCQALADYMTIWEKKGT-IKGVKVVYVGDGNNVAHSLMIAGTKLGAD 181
+PVINGLSD HP Q LADY TI E+ G ++G +VVY+GDGNN+A+S + G G D
Sbjct: 163 RIPVINGLSDMLHPAQLLADYQTIEEEFGQDLRGKRVVYIGDGNNLANSHIHMGILTGTD 222
Query: 182 VVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA 241
V V TP GYEP+ V+ +A ++G L +D + A++ ADV+YTDVW SMGQEAEA
Sbjct: 223 VTVVTPVGYEPNAGVL----MDAVKAGVEVHLTND-LDAIQGADVLYTDVWISMGQEAEA 277
Query: 242 EERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHA 301
+ RR+ FR +QV ++++ PD +F+HCLPAH GEE + + P S V+D+AENRLHA
Sbjct: 278 DIRRRAFRGYQVTPEMLETISPDGIFLHCLPAHYGEETVPEATEHPKSRVFDQAENRLHA 337
Query: 302 QKAVLALLLGGVK 314
QKA+L +LG +K
Sbjct: 338 QKALLYHVLGDMK 350
>gb|AAF61406.1|AF134842_1 (AF134842) ornithine transcarbamylase [Xenopus laevis]
Length = 351
Score = 275 bits (695), Expect = 6e-73
Identities = 150/310 (48%), Positives = 204/310 (65%), Gaps = 4/310 (1%)
Query: 3 VSLKGRDLLCLQDYTPEEIWTILETAKMLK--IWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
V LKG +LL L++YT EEI +L A LK I QK G+ LL+GK+LAMIF+K STRT
Sbjct: 32 VQLKGGNLLTLKNYTAEEIKYLLWVATDLKYRIKQK-GEYVPLLQGKSLAMIFEKRSTRT 90
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
R+S E A LGGH +L QD+ L E++ DTARVLS DA++ARVY D++ LAK
Sbjct: 91 RLSNETGFALLGGHPCFLTTQDIHLGVNESLKDTARVLSGMTDAVLARVYCQTDLDLLAK 150
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGA 180
A +P++NGLSD HP Q LADY+T+ E G + G+ + ++GDGNNV +S+M++ K G
Sbjct: 151 EAKIPIVNGLSDMYHPIQILADYLTLQEHYGHLNGLTISWIGDGNNVLNSIMMSAAKFGM 210
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
++ +ATP+GYEPD VI A+Q + E G + ++P++A A+V+ TD W SMGQE E
Sbjct: 211 NLRIATPKGYEPDSAVISAAKQFSKEFGTKLFMTNEPLEAATGANVLVTDTWVSMGQEEE 270
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
++R K F +Q+ K A PD+ F+HCLP + EEV D V SP S+V+ EAENR
Sbjct: 271 KKKRLKDFNGYQITMQTGKVASPDWTFLHCLP-RKPEEVDDAVFYSPKSLVFPEAENRKW 329
Query: 301 AQKAVLALLL 310
AV+ LL
Sbjct: 330 TVMAVMVALL 339
>sp|P31326|OTC_RANCA ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OTCASE) (ORNITHINE
TRANSCARBAMYLASE) >gi|477221|pir||A48421 ornithine
transcarbamylase - bullfrog >gi|213684|gb|AAA49528.1|
(M95193) ornithine carbamoyltransferase [Rana
catesbeiana] >gi|2522250|dbj|BAA22775.1| (D38304)
ornithine transcarbamylase [Rana catesbeiana]
Length = 350
Score = 274 bits (694), Expect = 8e-73
Identities = 146/307 (47%), Positives = 203/307 (65%), Gaps = 2/307 (0%)
Query: 5 LKGRDLLCLQDYTPEEIWTILETAKMLKIWQKI-GKPHRLLEGKTLAMIFQKPSTRTRVS 63
LKGRDLL L++Y+ EEI +L A LK K G+ LL+GK+LAMIF+K STRTR+S
Sbjct: 33 LKGRDLLTLKNYSAEEIKYLLWVAADLKYRIKEKGEYLPLLQGKSLAMIFEKRSTRTRLS 92
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
E A LGGH +L QD+ L E++ DTARVLS DA++ARVY D+E LA+ AS
Sbjct: 93 TETGFALLGGHPSFLTTQDIHLGVNESLKDTARVLSGMTDAVLARVYHQSDLEVLAEEAS 152
Query: 124 VPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVV 183
+P++NGLSD HP Q LADY+TI E G +KG+ + ++GDGNNV HS+M++ K G +
Sbjct: 153 IPIVNGLSDDYHPIQILADYLTIQEHYGHLKGLTISWIGDGNNVLHSIMMSAAKFGMHLH 212
Query: 184 VATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEE 243
+ATP+GYEP+ + + A+Q + E G + +DP++A A+V+ TD W SMGQE E ++
Sbjct: 213 IATPKGYEPNSSLTEAAKQFSKECGTKLLMTNDPLEAANGANVLVTDTWVSMGQEEEKKK 272
Query: 244 RRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQK 303
R F+ +Q+ K A P+++F+HCLP + EEV D+V P S+V+ EAENR
Sbjct: 273 RLLDFKGYQITMKTAKLAAPNWIFLHCLP-RKPEEVDDEVFYCPKSLVFQEAENRKWTIM 331
Query: 304 AVLALLL 310
V+ LL
Sbjct: 332 GVMVSLL 338
>gb|AAK41159.1| Ornithine carbamoyltransferase (argF) [Sulfolobus solfataricus]
Length = 307
Score = 272 bits (688), Expect = 4e-72
Identities = 147/306 (48%), Positives = 201/306 (65%), Gaps = 2/306 (0%)
Query: 6 KGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFE 65
+G+ LLCL D+ EI +LE + ++K + K L GK +A++F+KPSTRTRVS E
Sbjct: 3 RGKSLLCLLDFQTHEIEKMLEVSFLMKSYVYYNKVPNSLSGKRVALLFEKPSTRTRVSTE 62
Query: 66 VAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVP 125
+A++ LGG + LN QDLQ RGE I DT RVL R V+ I ARV +H + L + + VP
Sbjct: 63 LAVSLLGGIPIVLNKQDLQWSRGELIEDTGRVLGRVVNGIGARVLNHLTLVKLKESSGVP 122
Query: 126 VINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGN-NVAHSLMIAGTKLGADVVV 184
V N LSD SHP QALAD MTI E+ G VK+ +VGDG+ NV SLM KLG ++ V
Sbjct: 123 VFNLLSDLSHPLQALADLMTIRERFGN-NLVKIAFVGDGSDNVLLSLMAIVAKLGLELHV 181
Query: 185 ATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEER 244
ATP+ +P + + K + A ++G E DP +AV+ V+YTDVW SMGQE AE++
Sbjct: 182 ATPKELKPRDDLYKIISEIAEDTGSVIEFHEDPYEAVRGVHVVYTDVWVSMGQENIAEQK 241
Query: 245 RKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKA 304
+++ + ++V DL+K+A D +FMHCLPA+RGEEV +VID S VWD+AENRL+ A
Sbjct: 242 KRMLQNYRVTADLMKYAVKDAIFMHCLPANRGEEVDPEVIDGSKSAVWDQAENRLYTTMA 301
Query: 305 VLALLL 310
V +L +
Sbjct: 302 VFSLFI 307
>gb|AAF61407.1|AF134843_1 (AF134843) ornithine transcarbamylase [Raja sp.]
Length = 353
Score = 271 bits (685), Expect = 9e-72
Identities = 147/297 (49%), Positives = 195/297 (65%), Gaps = 4/297 (1%)
Query: 4 SLKGRDLLCLQDYTPEEIWTILETAKMLK--IWQKIGKPHRLLEGKTLAMIFQKPSTRTR 61
+LKGR LL L+D++ EEI L TA LK I QK G+ LL+GK++AMIF+K STRTR
Sbjct: 35 ALKGRHLLSLKDFSGEEIKQFLWTAADLKMRIKQK-GEILPLLQGKSIAMIFEKRSTRTR 93
Query: 62 VSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKY 121
+S E A LGGH +L QD+ L E+ DTARVLS D I+ARVY H D+E LA+
Sbjct: 94 LSTETGFALLGGHPCFLTTQDIHLGVNESRKDTARVLSGMTDVILARVYKHSDLEQLAED 153
Query: 122 ASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGAD 181
++PV+NGLS+ HP Q LADY+T+ E G++ G+ + ++GDGNNV +S M++ KLG
Sbjct: 154 GTIPVVNGLSEMYHPIQILADYLTLQEHFGSLNGLTLSWIGDGNNVLNSFMMSAPKLGMH 213
Query: 182 VVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA 241
+ VATP+G+EPD V K A+ A E G +DPV+A A+ + TD W SMGQE E
Sbjct: 214 LNVATPKGFEPDADVTKVAKSLAGECGTKLFFTNDPVEAASGANALVTDTWVSMGQEDEK 273
Query: 242 EERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENR 298
ER K F +Q+ K A P++ F+HCLP + EEV D+V SP S+V+ EAENR
Sbjct: 274 AERLKAFHGYQITMKTGKSAAPNWTFLHCLP-RKPEEVDDEVFYSPRSLVFQEAENR 329
>gb|AAF61408.1|AF134844_1 (AF134844) ornithine transcarbamylase [Sceloporus undulatus]
Length = 356
Score = 266 bits (672), Expect = 3e-70
Identities = 146/309 (47%), Positives = 201/309 (64%), Gaps = 2/309 (0%)
Query: 3 VSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKI-GKPHRLLEGKTLAMIFQKPSTRTR 61
V LKGRDLL LQ+++ EEI +L + LK K G+ LL+GK+LA IF+K STRTR
Sbjct: 37 VQLKGRDLLTLQNFSAEEIKYLLWVSADLKERIKHRGEYLPLLQGKSLATIFEKRSTRTR 96
Query: 62 VSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKY 121
+S E A LGGH +L A+D+ L E I DTARVLS DAI+ARV H D+E LAK
Sbjct: 97 LSTETGFALLGGHPCFLTAEDIHLGINENITDTARVLSTMTDAILARVCKHHDLELLAKE 156
Query: 122 ASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGAD 181
A +PVINGLSD HP Q LADY+T+ E G++ G+ + ++GDGNNV +S+M++ K G +
Sbjct: 157 ALIPVINGLSDSEHPIQILADYLTLQEHYGSLNGLTLCWIGDGNNVLNSIMLSAAKFGMN 216
Query: 182 VVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA 241
+ +A P+G+EPD V K AE+ + + +P++A + A+V+ TD W SMGQE E
Sbjct: 217 LHIAIPKGFEPDTMVTKTAEEYSIKYCTRLFRTTNPLEAARGANVLITDTWISMGQEEEK 276
Query: 242 EERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHA 301
+ R K F+ +Q+ + K A P + F+HCLP + +EV D+V SP S+V+ EAENR
Sbjct: 277 QARLKAFQDYQITMQIGKVAAPGWTFLHCLP-RKPQEVDDEVFYSPQSLVFQEAENRKWT 335
Query: 302 QKAVLALLL 310
AV+ LL
Sbjct: 336 IMAVMVSLL 344
>sp|P96172|OTCA_VIBS2 ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (OTCASE)
>gi|2370582|emb|CAA71921.1| (Y11033) ornithine
carbamoyltransferase [Vibrio sp.]
Length = 301
Score = 257 bits (651), Expect = 9e-68
Identities = 132/302 (43%), Positives = 195/302 (63%), Gaps = 4/302 (1%)
Query: 9 DLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAM 68
+LL ++D + ++I +L AK +K + + L GK++ I++KPS RTRV+F++ +
Sbjct: 3 NLLSVKDLSKQQILDLLALAKAVKA--NPAEYSQALAGKSIVTIYEKPSLRTRVTFDIGI 60
Query: 69 AHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVIN 128
LGGHA+YL+AQ+ + ET+ D A +SR+ DAI+ARV HK +E L ++ SVPV+N
Sbjct: 61 HKLGGHAVYLDAQNGAIGERETVKDFAANISRWADAIVARVVSHKTLEGLVEHGSVPVVN 120
Query: 129 GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVVATPE 188
L D HPCQALAD++TI E + VK+ YVG+GNNV HSLM+ G LGA+V P
Sbjct: 121 SLCDLYHPCQALADFLTISEHYEDVSKVKLAYVGEGNNVTHSLMLTGAILGAEVTAVCPR 180
Query: 189 GYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRKIF 248
G PD +++K A A SGG + D + A+ D DVIY D W SMG + + ++ +
Sbjct: 181 GSSPDAQIVKQAMALAEISGGKINVT-DNLDAIVDYDVIYGDTWVSMGDDTPLAQVKEKY 239
Query: 249 RPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVLAL 308
P+Q+NK L+ ++ +HC PAHR E+T +V+D +S+++D+AENR+HAQ AVL
Sbjct: 240 MPYQINKALLMRTGIKHV-LHCQPAHRELEITSEVMDGEHSLIFDQAENRMHAQNAVLLT 298
Query: 309 LL 310
LL
Sbjct: 299 LL 300
>emb|CAB95022.1| (AJ252021) ornithine carbamoyltransferase [Moritella sp. 2693]
Length = 301
Score = 255 bits (645), Expect = 4e-67
Identities = 131/302 (43%), Positives = 194/302 (63%), Gaps = 4/302 (1%)
Query: 9 DLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAM 68
+LL ++D + ++I +L AK +K + + L GK++ I++KPS RTRV+F++ +
Sbjct: 3 NLLSVKDLSKQQILDLLALAKAVKA--NPAEYSQALAGKSIVTIYEKPSLRTRVTFDIGI 60
Query: 69 AHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVIN 128
LGGHA+YL+AQ+ + ET+ D A +SR+ DAI+ARV HK +E L ++ SVPV+N
Sbjct: 61 HKLGGHAVYLDAQNGAIGERETVKDFAANISRWADAIVARVVSHKTLEGLVEHGSVPVVN 120
Query: 129 GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVVATPE 188
L D HPCQALAD++TI E + VK+ YVG+GNNV HSLM+ G LGA+V P
Sbjct: 121 SLCDLYHPCQALADFLTISEHYEDVSKVKLAYVGEGNNVTHSLMLTGAILGAEVTAVCPR 180
Query: 189 GYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRKIF 248
G PD +++K A A SGG + D + + D DVIY D W SMG + + ++ +
Sbjct: 181 GSSPDAQIVKQAMALAEISGGKINVT-DNLDDIVDYDVIYGDTWVSMGDDTPLAQVKEKY 239
Query: 249 RPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVLAL 308
P+Q+NK L+ ++ +HC PAHR E+T +V+D +S+++D+AENR+HAQ AVL
Sbjct: 240 MPYQINKALLMRTGIKHV-LHCQPAHRELEITSEVMDGEHSLIFDQAENRMHAQNAVLLT 298
Query: 309 LL 310
LL
Sbjct: 299 LL 300
>sp|P31317|OTC_SCHPO ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OTCASE) (ORNITHINE
TRANSCARBAMYLASE) >gi|279491|pir||OWZP ornithine
carbamoyltransferase (EC 2.1.3.3) - fission yeast
(Schizosaccharomyces pombe) >gi|4908|emb|CAA45133.1|
(X63577) ornithine carbamoyltransferase
[Schizosaccharomyces pombe] >gi|1204211|emb|CAA93560.1|
(Z69727) ornithine carbamoyltransferase precursor
[Schizosaccharomyces pombe]
Length = 327
Score = 254 bits (641), Expect = 1e-66
Identities = 143/309 (46%), Positives = 194/309 (62%), Gaps = 7/309 (2%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRL------LEGKTLAMIFQKPSTRTR 61
R LL ++D + EI +++ + +K K +R L + +AMIF K STRTR
Sbjct: 8 RHLLSIRDLSRGEIVKLIDRSSEIKQAYKQNFQNRRSVQMSGLSSQNVAMIFSKRSTRTR 67
Query: 62 VSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKY 121
VS E A++ LGG+A++L D+QL E++ DT++V+S V I+ARV + DV LAK+
Sbjct: 68 VSVESAVSCLGGNAMFLGKDDIQLGVNESLYDTSKVISSMVSGIVARVNKYSDVATLAKH 127
Query: 122 ASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGAD 181
AS PVINGL D HP QALAD +TI E + G+KV +VGD NNV H LMIA K+G
Sbjct: 128 ASCPVINGLCDTFHPLQALADLLTIKETFKSFDGLKVAWVGDANNVLHDLMIANAKVGIH 187
Query: 182 VVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA 241
VA P+ + ++ + A E+G +FE+++DP AVK+AD++ TD W SMGQEAE
Sbjct: 188 TSVAKPKDVNVRDDILSIVNEAANENGSTFEIVNDPKVAVKNADIVVTDTWISMGQEAEK 247
Query: 242 EERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHA 301
E+R K F FQV +++K AKP FMHCLP H EEV+D+V NS+V+ EAENR
Sbjct: 248 EQRLKQFTGFQVTGEIMKLAKPSCKFMHCLPRH-PEEVSDEVFYGENSLVFQEAENRKWT 306
Query: 302 QKAVLALLL 310
AVL LL
Sbjct: 307 TVAVLEALL 315
>emb|CAB95016.1| (AJ252020) ornithine carbamoyltransferase [Moritella sp. 2674]
Length = 301
Score = 252 bits (638), Expect = 3e-66
Identities = 131/307 (42%), Positives = 194/307 (62%), Gaps = 14/307 (4%)
Query: 9 DLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAM 68
+LL ++D + ++I +L AK +K + + L GK++ I++K S RTRV+F++ +
Sbjct: 3 NLLSVKDLSKQQILDLLALAKAVKA--NPAEYSQALAGKSIVTIYEKQSLRTRVTFDIGI 60
Query: 69 AHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVIN 128
LGGHA+YL+AQ+ + ET+ D A +SR+ DAI+ARV HK +E L ++ SVPV+N
Sbjct: 61 HKLGGHAVYLDAQNGAIGERETVKDFAANISRWADAIVARVMSHKTLEGLVEHGSVPVVN 120
Query: 129 GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVVATPE 188
L D HPCQALAD++TI E + VK+ Y+G+GNNV HSLM+ G LGA+V P
Sbjct: 121 SLCDLYHPCQALADFLTISEHYEDVSKVKLAYIGEGNNVTHSLMLTGAILGAEVTAVCPR 180
Query: 189 GYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRKIF 248
G PD +++K A A SGG + D + + D DVIY D W SMG + + ++ +
Sbjct: 181 GSSPDAQIVKQAMALAEISGGKINVT-DNLDDIVDYDVIYGDTWVSMGDDTPLAQVKEKY 239
Query: 249 RPFQVNKDL-----VKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQK 303
P+Q+NK+L +KH +HC PAHR E+T +V+D +S+++D+AENR+HAQ
Sbjct: 240 MPYQINKELLIRTGIKHV------LHCQPAHRELEITSEVMDGEHSLIFDQAENRMHAQN 293
Query: 304 AVLALLL 310
AVL LL
Sbjct: 294 AVLLTLL 300
>sp|Q59283|OTCA_CORGL ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (OTCASE)
>gi|3273712|gb|AAC24816.1| (AF049897) ornithine
carbamoyltransferase [Corynebacterium glutamicum]
>gi|4104080|gb|AAD01932.1| (AF031518) ornithine
carbamolytransferase [Corynebacterium glutamicum]
Length = 319
Score = 252 bits (636), Expect = 5e-66
Identities = 140/311 (45%), Positives = 194/311 (62%), Gaps = 12/311 (3%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEG-KTLAMIFQKPSTRTRVSFEV 66
R L D TP E +L A LK +P LEG K++A++F K STRTR SF+
Sbjct: 8 RHFLADDDLTPAEQAEVLTLAAKLKAAPFSERP---LEGPKSVAVLFDKTSTRTRFSFDA 64
Query: 67 AMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPV 126
+AHLGGHA+ +++ Q+ +GE++ DTA VLSRYV+AI+ R Y H + +A+ ++VP+
Sbjct: 65 GIAHLGGHAIVVDSGSSQMGKGESLQDTAAVLSRYVEAIVWRTYAHSNFHAMAETSTVPL 124
Query: 127 INGLSDFSHPCQALADYMTIWEK------KGTIKGVKVVYVGDG-NNVAHSLMIAGTKLG 179
+N LSD HPCQ LAD TI E +KG K VY+GDG NN+A+S MI G
Sbjct: 125 VNSLSDDLHPCQILADLQTIVENLSPEEGPAGLKGKKAVYLGDGDNNMANSYMIGFATAG 184
Query: 180 ADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEA 239
D+ + PEG++P + ++ AE+ E+G ++ D + V ADV+ TD W SMG E
Sbjct: 185 MDISIIAPEGFQPRAEFVERAEKRGQETGAKV-VVTDSLDEVAGADVVITDTWVSMGMEN 243
Query: 240 EAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRL 299
+ +R F P+QVN +++ A +F+HCLPA+RG+EV VID P S V+DEAENRL
Sbjct: 244 DGIDRTTPFVPYQVNDEVMAKANDGAIFLHCLPAYRGKEVAASVIDGPASKVFDEAENRL 303
Query: 300 HAQKAVLALLL 310
HAQKA+L LL
Sbjct: 304 HAQKALLVWLL 314
>pir||T46742 ornithine carbamoyltransferase (EC 2.1.3.3) [validated] -
Lactobacillus sakei >gi|2764612|emb|CAA04683.1|
(AJ001330) ornithine transcarbamoylase [Lactobacillus
sakei]
Length = 337
Score = 248 bits (626), Expect = 8e-65
Identities = 136/327 (41%), Positives = 198/327 (59%), Gaps = 20/327 (6%)
Query: 6 KGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFE 65
+GR LL +D+T E+ +++ + LK +K G PH LEGK +A++F+K STRTR +F
Sbjct: 7 QGRSLLAEKDFTKSELEYLIDFSLHLKDLKKKGIPHHYLEGKNIALLFEKNSTRTRAAFT 66
Query: 66 VAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVP 125
A LG H +L D+QL + E++ DTA+VL D I R K VEDLAKY+ VP
Sbjct: 67 TAAIDLGAHPEFLGKNDIQLGKKESVEDTAKVLGSMFDGIEFRALA-KVVEDLAKYSGVP 125
Query: 126 VINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLGADVVV 184
V NGL+D HP Q +AD+MT+ E G +KGV + YVGDG NN+A+SL++ G+ LG ++ +
Sbjct: 126 VWNGLTDEWHPTQMIADFMTVKENFGKLKGVTLTYVGDGRNNMANSLLVTGSMLGVNIHI 185
Query: 185 ATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEER 244
P+ +P ++V AE A E+G + D VK +DV+YTDVW SMG+E + EER
Sbjct: 186 VAPDSLQPTQEVRDLAEGYAKETGSKNMITSDVDAGVKGSDVLYTDVWVSMGEEDKFEER 245
Query: 245 RKIFRPFQVNKDLVKHAKPDYM-FMHCLPAH-----------------RGEEVTDDVIDS 286
+ +P+Q+N D+VK + M MHCLPA + E+TD+ S
Sbjct: 246 VNLLKPYQINMDMVKKTGNENMIIMHCLPAFHDIETEYGKKIDEQFGIQEMEITDEAFRS 305
Query: 287 PNSVVWDEAENRLHAQKAVLALLLGGV 313
+ ++EAENR+H+ KA++A LG +
Sbjct: 306 KYARQFEEAENRMHSIKAIMAATLGNL 332
>gb|AAB93999.1| (AF008219) ArcB [Borrelia afzelii]
Length = 328
Score = 247 bits (623), Expect = 2e-64
Identities = 140/326 (42%), Positives = 199/326 (60%), Gaps = 18/326 (5%)
Query: 4 SLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVS 63
+L+ R L L D+T ++I +L+ + LK + G + L+GK + +IF+K STRTR +
Sbjct: 3 NLRNRSFLNLLDFTSKDIKYLLDLSIDLKKSKYAGIEVQKLKGKNIVIIFEKDSTRTRCA 62
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
FE+A G + YL + Q+ E++ DTARVL R DAI R + + VE LA Y++
Sbjct: 63 FEIAAYDQGANITYLGPKGNQIGVKESMKDTARVLGRMYDAIGFRGFSQETVECLANYSN 122
Query: 124 VPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLGADV 182
VPV NGL+D SHP Q LAD MTI E KG++KG+K+V+ GDG N+A+SL+ +G D
Sbjct: 123 VPVYNGLTDISHPTQILADLMTIKEHKGSLKGIKIVFCGDGRGNIANSLLKGCAIMGLDF 182
Query: 183 VVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAE 242
+ P+ PD + A+ A +SGG + +AVK ADV+YTDVW SMG+E+ E
Sbjct: 183 RIFAPKELFPDSNLTLKAKSLALKSGGKITITDSKEEAVKCADVVYTDVWVSMGEESNWE 242
Query: 243 ERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHR-----------------GEEVTDDVID 285
+R + + +QVNK+L+ AK D +FMHCLPA G EVT+++ +
Sbjct: 243 DRINLLKLYQVNKELMCMAKDDAIFMHCLPAFHDLSTVVGRDIFDKYGLDGIEVTEEIFE 302
Query: 286 SPNSVVWDEAENRLHAQKAVLALLLG 311
S NSVV+D AENR+HA KAV+ LG
Sbjct: 303 SKNSVVFDVAENRVHAIKAVMVSTLG 328
>pir||G81374 ornithine carbamoyltransferase (EC 2.1.3.3) Cj0994c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968429|emb|CAB73250.1| (AL139076) ornithine
carbamoyltransferase [Campylobacter jejuni]
Length = 306
Score = 246 bits (622), Expect = 2e-64
Identities = 126/303 (41%), Positives = 192/303 (62%), Gaps = 6/303 (1%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
+ L L+D++ EEI +++ A LK +P +LL+ KTLAMIF+K STRTR++FE+A
Sbjct: 2 KHFLTLRDFSKEEILSLVNHASELK-----KEPKKLLQDKTLAMIFEKNSTRTRMAFELA 56
Query: 68 MAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVI 127
+ LGG AL+L++ DLQL RGE + DTARV+ VD +M RV H+ + + A+Y+ PVI
Sbjct: 57 ITELGGKALFLSSNDLQLSRGEPVKDTARVIGAMVDFVMMRVNKHETLLEFARYSKAPVI 116
Query: 128 NGLSDFSHPCQALADYMTIWEKKGTIKGV-KVVYVGDGNNVAHSLMIAGTKLGADVVVAT 186
N LS+ HP Q L D TI E G+ KV ++GD NN+ +S +I LG ++ +A
Sbjct: 117 NALSELYHPTQVLGDLFTIKEWNKMQNGIAKVAFIGDSNNMCNSWLITAAILGFEISIAM 176
Query: 187 PEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRK 246
P+ Y+ ++ ++A + A SG L +D +A+KD DV+ TD W SMG+E E E + K
Sbjct: 177 PKNYKISPEIWEFAMKQALISGAKISLGYDKFEALKDKDVVITDTWVSMGEENEKERKIK 236
Query: 247 IFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVL 306
F F +++ + A D + +HCLPA+RG EV++++ + V+++EA NRL+ KA+L
Sbjct: 237 EFEGFMIDEKAMSVANKDAILLHCLPAYRGYEVSEEIFEKHADVIFEEARNRLYVVKALL 296
Query: 307 ALL 309
L
Sbjct: 297 CFL 299
>pir||A70205 ornithine carbamoyltransferase, catabolic (arcB) homolog - Lyme
disease spirochete >gi|2688788|gb|AAC67190.1| (AE001183)
ornithine carbamoyltransferase, catabolic (arcB)
[Borrelia burgdorferi]
Length = 328
Score = 244 bits (616), Expect = 1e-63
Identities = 140/329 (42%), Positives = 199/329 (59%), Gaps = 19/329 (5%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
M+ +L+ R L L D+T ++I +L+ + LK + G + L+GK + +IF+K STRT
Sbjct: 1 MMYNLRNRSFLNLLDFTSKDIKYLLDLSINLKKSKYAGIEVQKLKGKNIVIIFEKDSTRT 60
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
R +FE+A G + YL ++ Q+ E++ DTARVL R DAI R + + VE LA
Sbjct: 61 RCAFEIAAYDQGANITYLGSKGNQMGSKESMIDTARVLGRMYDAIGFRGFSQQTVECLAN 120
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLG 179
Y++VPV NGL+D SHP Q LAD MTI E KG++KG+K+V+ GDG NVA+SL+ +G
Sbjct: 121 YSNVPVYNGLTDISHPTQILADLMTIKEHKGSLKGIKIVFCGDGRGNVANSLLKGCAIMG 180
Query: 180 ADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEA 239
D + P+ PD + A A ESGG + +AVK ADV+YTDVW SMG E+
Sbjct: 181 LDFRIFAPKELFPDPDLTLKARSLALESGGKITITDSKEEAVKCADVVYTDVWVSMG-ES 239
Query: 240 EAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHR-----------------GEEVTDD 282
E+R + + +QVNK+++ AK D +FMHCLPA G EVT++
Sbjct: 240 NWEDRINLLKAYQVNKEIMCMAKDDAIFMHCLPAFHDLNTVIGKDIFDKYGLDGIEVTEE 299
Query: 283 VIDSPNSVVWDEAENRLHAQKAVLALLLG 311
+ +S NSVV+D AENR+H KA++ LG
Sbjct: 300 IFESKNSVVFDVAENRVHTIKAIMVSTLG 328
>emb|CAB93580.1| (AJ250129) ornithine transcarbamylase [Lactococcus lactis]
Length = 354
Score = 243 bits (615), Expect = 1e-63
Identities = 140/330 (42%), Positives = 199/330 (59%), Gaps = 23/330 (6%)
Query: 6 KGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFE 65
+GR LL +D+TP EI +++ LK ++ PH LEGK +A++F K STRTR +F
Sbjct: 16 QGRSLLAEKDFTPAEINYLVDFGLHLKALKQQNIPHHYLEGKNIALLFAKTSTRTRAAFT 75
Query: 66 VAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVP 125
A LG H YL A D+QL E+ DTARVL DAI R + K+VEDLAKY+ VP
Sbjct: 76 TAAIDLGAHPEYLGANDIQLGIKESTEDTARVLGSMFDAIERRGFSQKEVEDLAKYSGVP 135
Query: 126 VINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLGADVVV 184
V NGL+D HP Q +AD+MT+ E G +KG+ +VYVGDG NN+A+SL++ G+ LG +V +
Sbjct: 136 VWNGLTDDWHPTQMIADFMTVKENFGYLKGLTLVYVGDGRNNMANSLIVTGSMLGVNVHI 195
Query: 185 ATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEER 244
P+ P ++V+ A + A +SG + + VK A++IY+DVW SMG E+ EER
Sbjct: 196 VAPDSLHPSKEVMDIANKFAEKSGAKPLATSNIEEGVKGANIIYSDVWVSMG-ESNWEER 254
Query: 245 RKIFRPFQVNKDLVKHA----KPDYMFMHCLPA-HRGE----------------EVTDDV 283
K+ P+++ D++K +FMHCLPA H E EVTD+V
Sbjct: 255 VKLLTPYRITMDMLKMTGNADNGKLIFMHCLPAFHDTETEYGKEIKEKYGLTEMEVTDEV 314
Query: 284 IDSPNSVVWDEAENRLHAQKAVLALLLGGV 313
S + ++EAENR+H+ KA++A LG +
Sbjct: 315 FRSKYARQFEEAENRMHSIKAIMAATLGNL 344
>gb|AAF86986.1|AF282249_5 (AF282249) ArcB [Lactococcus lactis subsp. lactis]
Length = 354
Score = 242 bits (611), Expect = 4e-63
Identities = 140/330 (42%), Positives = 198/330 (59%), Gaps = 23/330 (6%)
Query: 6 KGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFE 65
+GR LL +D+TP EI +++ LK ++ PH LEGK +A++F K STRTR +F
Sbjct: 16 QGRSLLAEKDFTPAEINYLVDFGLHLKALKQQNIPHHYLEGKNIALLFAKTSTRTRAAFT 75
Query: 66 VAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVP 125
A LG H YL A D+QL E+ DTARVL DAI R + K+VEDLAKY+ VP
Sbjct: 76 TAAIDLGAHPEYLGANDIQLGIKESTEDTARVLGSMFDAIERRGFSQKEVEDLAKYSGVP 135
Query: 126 VINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLGADVVV 184
V NGL+D HP Q +AD+MT+ E G +KG+ +VYVGDG NN+A+SL++ G+ LG +V +
Sbjct: 136 VWNGLTDDWHPTQMIADFMTVKENFGYLKGLTLVYVGDGRNNMANSLIVTGSMLGVNVHI 195
Query: 185 ATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEER 244
P+ P ++V+ A + A +SG + + VK A++IY+DVW SMG E+ EER
Sbjct: 196 VAPDSLHPSKEVMDIANKFAEKSGAKPLATSNIEEGVKGANIIYSDVWVSMG-ESNWEER 254
Query: 245 RKIFRPFQVNKDLVKHA----KPDYMFMHCLPA-HRGE----------------EVTDDV 283
K+ P+++ D++K +FMHCLPA H E EVTD V
Sbjct: 255 VKLLTPYRITMDMLKMTGNADNGKLIFMHCLPAFHDTETEYGKEIKEKYGLTEMEVTDAV 314
Query: 284 IDSPNSVVWDEAENRLHAQKAVLALLLGGV 313
S + ++EAENR+H+ KA++A LG +
Sbjct: 315 FRSKYARQFEEAENRMHSIKAIMAATLGNL 344
>sp|O08322|OTCA_LACPL ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (OTCASE)
>gi|1922883|emb|CAA68243.1| (X99978) anabolic ornithine
carbamoyltransferase [Lactobacillus plantarum]
Length = 340
Score = 239 bits (603), Expect = 4e-62
Identities = 136/327 (41%), Positives = 191/327 (57%), Gaps = 19/327 (5%)
Query: 6 KGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFE 65
+GR L DYTP E+ +++ A LK + PH L+GK +A++F+K STRTR +F
Sbjct: 6 EGRSFLKEIDYTPTELAYLIDFASHLKTLKAHHIPHPYLQGKNIALLFEKTSTRTRSAFT 65
Query: 66 VAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVP 125
VA LG + +L D+Q E++ DTA+VL D I R + VEDLA Y+ VP
Sbjct: 66 VAANDLGANPEFLGKDDIQFGTKESVVDTAKVLGSMYDGIEFRGFKQSTVEDLATYSGVP 125
Query: 126 VINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLGADVVV 184
V NGL+D HP Q LAD++T+ E G +KG+ + YVGDG NN+A+SL++AG LG ++ +
Sbjct: 126 VWNGLTDEWHPTQILADFLTLKEHFGHLKGLTLAYVGDGRNNMANSLLVAGAMLGINIAI 185
Query: 185 ATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEER 244
P +P V+ A+Q A +G + + DP +AV AD +YTDVW SMG++ + ER
Sbjct: 186 GAPVALQPAPAVVALAQQYAQAAGSTVVITADPQQAVTQADALYTDVWVSMGEQVDYGER 245
Query: 245 RKIFRPFQVNKDLV-KHAKPDYMFMHCLP----------AHRGE-------EVTDDVIDS 286
K PFQ+N L+ K + MHCLP A GE E+TDDV S
Sbjct: 246 IKQLLPFQINTTLLAATGKSSTIVMHCLPALHDLKTQLGAKLGEQYGMTAFEITDDVFQS 305
Query: 287 PNSVVWDEAENRLHAQKAVLALLLGGV 313
+VV++EA NR+ A KAV+A LG +
Sbjct: 306 KQAVVFEEAGNRMPAIKAVMAATLGNL 332
>sp|O31018|OTCC_RHIET ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC (OTCASE)
>gi|2555171|gb|AAC46019.1| (AF025543) ArcB; catabolic
ornithine carbamoyltransferase; cOTCase [Rhizobium etli]
Length = 334
Score = 238 bits (600), Expect = 8e-62
Identities = 145/333 (43%), Positives = 188/333 (55%), Gaps = 22/333 (6%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
M +L+ R LL +QDYTP E +L+ A+ LK + L+GK + +IF+K STRT
Sbjct: 1 MSFNLRNRSLLTVQDYTPREFRYLLDLARDLKRAKYARTEQEHLKGKEICLIFEKTSTRT 60
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
R +FEVA + G + YL+ Q+ E+ DTARVL R DAI R K VE LAK
Sbjct: 61 RCAFEVACSDQGANVTYLDPSGSQIGHKESFKDTARVLGRMYDAIEYRGSAQKGVETLAK 120
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKG-TIKGVKVVYVGD-GNNVAHSLMIAGTKL 178
YA VPV NGL+D HP Q +AD MT+ E I +K YVGD +N+ HSL+I G L
Sbjct: 121 YAGVPVYNGLTDEYHPTQMIADVMTMREHSDKPIAEIKYAYVGDTRSNMGHSLLIVGCLL 180
Query: 179 GADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQE 238
G DV + P P E+ +K A+ SG + DP +AVKD D I+TDVW SMG+
Sbjct: 181 GMDVRICGPRSLWPSEEYMKIAKVLQQASGARLLVTEDPREAVKDVDFIHTDVWVSMGEP 240
Query: 239 AEA-EERRKIFRPFQVNKDLVK-HAKPDYMFMHCLPA------------------HRGEE 278
E ER K+ P+QVN+DL+K P FMHCLPA G E
Sbjct: 241 KEVWRERIKLLTPYQVNQDLMKATGNPQTKFMHCLPAFHDTETTLGKQIAEDYGMDNGLE 300
Query: 279 VTDDVIDSPNSVVWDEAENRLHAQKAVLALLLG 311
VT+DV +S +V +++AENRLH KA+L LG
Sbjct: 301 VTNDVFESEANVAFEQAENRLHTIKALLVATLG 333
>sp|P11066|OTC_ASPNG ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OTCASE) (ORNITHINE
TRANSCARBAMYLASE) >gi|279489|pir||OWASG ornithine
carbamoyltransferase (EC 2.1.3.3) precursor -
Aspergillus niger >gi|166492|gb|AAA32688.1| (M19158)
ornithine carbamoyl transferase precursor [Aspergillus
niger] >gi|225926|prf||1403322A Orn carbamoyl
transferase [Aspergillus niger]
Length = 370
Score = 237 bits (598), Expect = 1e-61
Identities = 141/317 (44%), Positives = 190/317 (59%), Gaps = 19/317 (5%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKP----HRLLEGKTLAMIFQKPSTRTRVS 63
R LL + D TP E T++ A K K G H L GKT+AM+F K STRTR+S
Sbjct: 44 RHLLSIADLTPTEFATLVRNASSHKRAIKSGSIPQSLHGALSGKTVAMMFSKRSTRTRIS 103
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
E A+ +GGH ++L D+QL E++ DTA V+S V+ I+ARV H DV DLAK+++
Sbjct: 104 TEGAVVQMGGHPMFLGKDDIQLGVNESLYDTAVVVSSMVECIVARVGKHADVADLAKHST 163
Query: 124 VPVINGLSDFSHPCQALADYMTIWEK-----KGTIK-----GVKVVYVGDGNNVAHSLMI 173
PVIN L D HP QA+AD+ TI E KG ++ G+K+ +VGD NNV + I
Sbjct: 164 KPVINALCDSYHPLQAIADFQTISEHFAASGKGKLEGLGLNGLKIAWVGDANNVLFDMAI 223
Query: 174 AGTKLGADVVVATPEGYEPDEKVIKWAEQ--NAAESGGSFELLHDPVKAVKDADVIYTDV 231
+ K+G DV VATP+GYE +++++ E+ +S G + P +AVK ADV+ TD
Sbjct: 224 SARKMGVDVAVATPKGYEIPKEMLEIIEKAGEGVKSPGKLVQTNVPEEAVKGADVLVTDT 283
Query: 232 WASMGQEAEAEERRKIFRPFQVNKDLVKH--AKPDYMFMHCLPAHRGEEVTDDVIDSPNS 289
W SMGQE EA +R + F FQ+ +L K AK + FMHCLP H EEV D+V S
Sbjct: 284 WVSMGQEEEAAKRLRDFAGFQITSELAKRGGAKEGWRFMHCLPRH-PEEVADEVFYGHRS 342
Query: 290 VVWDEAENRLHAQKAVL 306
+V+ EAENRL A + L
Sbjct: 343 LVFPEAENRLWAAISAL 359
>sp|P11803|OTC_EMENI ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OTCASE) (ORNITHINE
TRANSCARBAMYLASE) >gi|168017|gb|AAA50816.1| (M29819)
ornithine carbamoyltransferase [Aspergillus nidulans]
Length = 359
Score = 237 bits (598), Expect = 1e-61
Identities = 143/317 (45%), Positives = 192/317 (60%), Gaps = 20/317 (6%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGK-PHRL---LEGKTLAMIFQKPSTRTRVS 63
R L + D +P E T++ A K K G P L L GKT+AMIF K STRTRVS
Sbjct: 34 RHFLSIADLSPSEFATLVRNASSHKRAIKSGSMPQNLQGSLLGKTVAMIFSKRSTRTRVS 93
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
E A+ +GGH ++L D+QL E++ DT+ V+S V I+ARV H +V DLAK++S
Sbjct: 94 TEGAVVQMGGHPMFLGKDDIQLGVNESLYDTSVVISSMVSCIVARVGKHAEVADLAKHSS 153
Query: 124 VPVINGLSDFSHPCQALADYMTIWE---------KKGTIKGVKVVYVGDGNNVAHSLMIA 174
VPVIN L D HP QA+AD+ TI+E ++G+K+ +VGD NNV + IA
Sbjct: 154 VPVINALCDSFHPLQAVADFQTIYEAFTPKAHHLSSLGLEGLKIAWVGDANNVLFDMAIA 213
Query: 175 GTKLGADVVVATPEGYEPDE---KVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDV 231
TK+G D+ VATP+GYE ++IK A + ++ G + + P +AVKDAD++ TD
Sbjct: 214 ATKMGVDIAVATPKGYEIPPHMLELIKSAGEGVSKPGKLLQ-TNIPEEAVKDADILVTDT 272
Query: 232 WASMGQEAEAEERRKIFRPFQVNKDLVKH--AKPDYMFMHCLPAHRGEEVTDDVIDSPNS 289
W SMGQE E +R K F FQ+ +L K AK + FMHCLP H EEV+D+V S S
Sbjct: 273 WVSMGQEEEKAQRLKEFDGFQITAELAKRGGAKEGWKFMHCLPRH-PEEVSDEVFYSNRS 331
Query: 290 VVWDEAENRLHAQKAVL 306
+V+ EAENRL A + L
Sbjct: 332 LVFPEAENRLWAAISAL 348
>pir||OWASN ornithine carbamoyltransferase (EC 2.1.3.3) precursor - Emericella
nidulans
Length = 397
Score = 237 bits (598), Expect = 1e-61
Identities = 143/317 (45%), Positives = 192/317 (60%), Gaps = 20/317 (6%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGK-PHRL---LEGKTLAMIFQKPSTRTRVS 63
R L + D +P E T++ A K K G P L L GKT+AMIF K STRTRVS
Sbjct: 72 RHFLSIADLSPSEFATLVRNASSHKRAIKSGSMPQNLQGSLLGKTVAMIFSKRSTRTRVS 131
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
E A+ +GGH ++L D+QL E++ DT+ V+S V I+ARV H +V DLAK++S
Sbjct: 132 TEGAVVQMGGHPMFLGKDDIQLGVNESLYDTSVVISSMVSCIVARVGKHAEVADLAKHSS 191
Query: 124 VPVINGLSDFSHPCQALADYMTIWE---------KKGTIKGVKVVYVGDGNNVAHSLMIA 174
VPVIN L D HP QA+AD+ TI+E ++G+K+ +VGD NNV + IA
Sbjct: 192 VPVINALCDSFHPLQAVADFQTIYEAFTPKAHHLSSLGLEGLKIAWVGDANNVLFDMAIA 251
Query: 175 GTKLGADVVVATPEGYEPDE---KVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDV 231
TK+G D+ VATP+GYE ++IK A + ++ G + + P +AVKDAD++ TD
Sbjct: 252 ATKMGVDIAVATPKGYEIPPHMLELIKSAGEGVSKPGKLLQ-TNIPEEAVKDADILVTDT 310
Query: 232 WASMGQEAEAEERRKIFRPFQVNKDLVKH--AKPDYMFMHCLPAHRGEEVTDDVIDSPNS 289
W SMGQE E +R K F FQ+ +L K AK + FMHCLP H EEV+D+V S S
Sbjct: 311 WVSMGQEEEKAQRLKEFDGFQITAELAKRGGAKEGWKFMHCLPRH-PEEVSDEVFYSNRS 369
Query: 290 VVWDEAENRLHAQKAVL 306
+V+ EAENRL A + L
Sbjct: 370 LVFPEAENRLWAAISAL 386
>dbj|BAA35119.1| (AB020737) ornithine carbamoyltransferase [Aspergillus oryzae]
Length = 372
Score = 237 bits (598), Expect = 1e-61
Identities = 141/312 (45%), Positives = 190/312 (60%), Gaps = 20/312 (6%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGK-PHRLL---EGKTLAMIFQKPSTRTRVS 63
R L + D T E T++ A K K G P LL G+T+AM+F K STRTR+S
Sbjct: 47 RHFLSIADLTSTEFATLVRNASSHKRTIKSGSIPQNLLGSMTGQTVAMLFSKRSTRTRIS 106
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
E A+ LGGH ++L D+QL E++ D+A V+S V I+ARV H +V DLAK+++
Sbjct: 107 TEGAVVRLGGHPMFLGKDDIQLGVNESLYDSAVVISSMVSCIVARVGKHAEVADLAKHST 166
Query: 124 VPVINGLSDFSHPCQALADYMTIWE---------KKGTIKGVKVVYVGDGNNVAHSLMIA 174
VPVIN L D HP QA+AD+ TI+E ++G+K+ +VGD NNV + IA
Sbjct: 167 VPVINALCDSFHPLQAIADFQTIYETFTPKAHRSDSLGLEGLKIAWVGDANNVLFDMAIA 226
Query: 175 GTKLGADVVVATPEGYE---PDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDV 231
TK+G D+ VATP+GYE P ++IK A ++ G E + P +AVK AD++ TD
Sbjct: 227 ATKMGIDIAVATPKGYEIPAPMLELIKQASNGVSKPGKIIE-TNVPEEAVKGADILVTDT 285
Query: 232 WASMGQEAEAEERRKIFRPFQVNKDLVKH--AKPDYMFMHCLPAHRGEEVTDDVIDSPNS 289
W SMGQEAE+ +R K F FQ+ +L K A + FMHCLP H EEV+D+V SP S
Sbjct: 286 WVSMGQEAESIKRVKDFEGFQITSELAKRGGANEGWKFMHCLPRH-PEEVSDEVFYSPRS 344
Query: 290 VVWDEAENRLHA 301
+V+ EAENRL A
Sbjct: 345 LVFPEAENRLWA 356
>pir||B81801 ornithine carbamoyltransferase (EC 2.1.3.3) NMA1762 [imported] -
Neisseria meningitidis (group A strain Z2491)
>gi|7380404|emb|CAB84990.1| (AL162757) ornithine
transcarbamoylase [Neisseria meningitidis Z2491]
Length = 331
Score = 236 bits (596), Expect = 2e-61
Identities = 139/330 (42%), Positives = 189/330 (57%), Gaps = 21/330 (6%)
Query: 3 VSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRV 62
++LK R L L D+TPEEI L+ A LK +K G+ + ++GK +A+IF+K STRTR
Sbjct: 1 MNLKNRHFLKLLDFTPEEITAYLDLAAELKAAKKAGREIQRMKGKNIALIFEKTSTRTRC 60
Query: 63 SFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYA 122
+FEVA G YL Q+ E+I DTARVL R DAI R + + VE+LAKYA
Sbjct: 61 AFEVAARDQGAGVTYLEPSASQIGHKESIKDTARVLGRMYDAIEYRGFGQETVEELAKYA 120
Query: 123 SVPVINGLSDFSHPCQALADYMTIWEKKG-TIKGVKVVYVGDGN-NVAHSLMIAGTKLGA 180
VPV NGL++ HP Q LAD +T+ E G + YVGD N+ +SL+I G KLG
Sbjct: 121 GVPVFNGLTNEFHPTQMLADALTMREHSGKPLNQTAFAYVGDARYNMGNSLLILGAKLGM 180
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
DV + P+ P E +I A A E+G L + +AVK+ D I+TDVW SMG+ E
Sbjct: 181 DVRIGAPQSLWPSEGIIAAAHAAAKETGAKITLTENAHEAVKNVDFIHTDVWVSMGEPKE 240
Query: 241 A-EERRKIFRPFQVNKDLV-KHAKPDYMFMHCLPAH-----------------RGEEVTD 281
+ER + + ++V +L+ P FMHCLPA G EVT+
Sbjct: 241 VWQERIDLLKDYRVTPELMAASGNPQVKFMHCLPAFHNRETKVGEWIYETFGLNGVEVTE 300
Query: 282 DVIDSPNSVVWDEAENRLHAQKAVLALLLG 311
+V +SP S+V+D+AENR+H KAV+ LG
Sbjct: 301 EVFESPASIVFDQAENRMHTIKAVMVAALG 330
>gb|AAD32177.1|AF125563_2 (AF125563) ornithine carbomyltransferase [Neisseria meningitidis]
Length = 331
Score = 235 bits (594), Expect = 4e-61
Identities = 139/330 (42%), Positives = 189/330 (57%), Gaps = 21/330 (6%)
Query: 3 VSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRV 62
++LK R L L D+TPEEI L+ A LK +K G+ + ++GK +A+IF+K STRTR
Sbjct: 1 MNLKNRHFLKLLDFTPEEITAYLDLAAELKAAKKAGREIQRMKGKNIALIFEKTSTRTRC 60
Query: 63 SFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYA 122
+FEVA G YL Q+ E+I DTARVL R DAI R + + VE+LAKYA
Sbjct: 61 AFEVAARDQGAGVTYLEPSASQIGHKESIKDTARVLGRMYDAIEYRGFGQEVVEELAKYA 120
Query: 123 SVPVINGLSDFSHPCQALADYMTIWEKKG-TIKGVKVVYVGDGN-NVAHSLMIAGTKLGA 180
VPV NGL++ HP Q LAD +T+ E G + YVGD N+ +SL+I G KLG
Sbjct: 121 GVPVFNGLTNEFHPTQMLADALTMREHSGKPLNQTAFAYVGDARYNMGNSLLILGAKLGM 180
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
DV + P+ P E +I A A E+G L + +AVK+ D I+TDVW SMG+ E
Sbjct: 181 DVRIGAPQSLWPSEGIIAAAHAAAKETGAKITLTENAHEAVKNVDFIHTDVWVSMGEPKE 240
Query: 241 A-EERRKIFRPFQVNKDLV-KHAKPDYMFMHCLPAH-----------------RGEEVTD 281
+ER + + ++V +L+ P FMHCLPA G EVT+
Sbjct: 241 VWQERIDLLKDYRVTPELMAASGNPQVKFMHCLPAFHNRETKVGEWIYETFGLNGVEVTE 300
Query: 282 DVIDSPNSVVWDEAENRLHAQKAVLALLLG 311
+V +SP S+V+D+AENR+H KAV+ LG
Sbjct: 301 EVFESPASIVFDQAENRMHTIKAVMVAALG 330
>pir||F82066 ornithine carbamoyltransferase VC2508 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9657091|gb|AAF95650.1|
(AE004321) ornithine carbamoyltransferase [Vibrio
cholerae]
Length = 334
Score = 235 bits (594), Expect = 4e-61
Identities = 132/333 (39%), Positives = 194/333 (57%), Gaps = 22/333 (6%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
M +L+ R+ L L D+TP+EI +L+ + LK + G + L+GK +A+IF+K STRT
Sbjct: 1 MAFNLRNRNFLKLLDFTPKEIHFLLDLSAELKRAKYAGTEQKTLQGKNIALIFEKSSTRT 60
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
R +FEVA G Y+ Q+ E++ DTARVL R D I R + + VE L +
Sbjct: 61 RCAFEVAAFDQGAQVSYIGPSGSQIGHKESMKDTARVLGRMYDGIQYRGFGQEIVEVLGQ 120
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWE--KKGTIKGVKVVYVGDG-NNVAHSLMIAGTK 177
YA VPV NGL+D HP Q LAD +T+ E + + +K Y+GD NN+ +SLM+ K
Sbjct: 121 YAGVPVWNGLTDEFHPTQILADLLTMQEYGRSKQLHEMKFAYLGDARNNMGNSLMVGAAK 180
Query: 178 LGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQ 237
+G D+ + P+ Y P++ ++ ++ A ++G L + + VK D +YTDVW SMG+
Sbjct: 181 MGMDIRLVAPKAYWPNDALVATCQEIAKQTGAKITLTEEVQEGVKGCDFLYTDVWVSMGE 240
Query: 238 EAEA-EERRKIFRPFQVNKDLVK-HAKPDYMFMHCLPAH-----------------RGEE 278
A+A +ER + +P+QVN D++K P FMHCLPA +G E
Sbjct: 241 AADAWDERVALMKPYQVNMDVIKATGNPQVKFMHCLPAFHDDQTKVGQEIAAKYGMQGLE 300
Query: 279 VTDDVIDSPNSVVWDEAENRLHAQKAVLALLLG 311
VT++V +S S+V+DEAENRLH KAV+ LG
Sbjct: 301 VTEEVFESEYSIVFDEAENRLHTIKAVMVATLG 333
>pir||E81066 ornithine carbamoyltransferase, catabolic NMB1573 [imported] -
Neisseria meningitidis (group B strain MD58)
>gi|7226821|gb|AAF41926.1| (AE002508) ornithine
carbamoyltransferase, catabolic [Neisseria meningitidis
MC58]
Length = 331
Score = 235 bits (593), Expect = 6e-61
Identities = 138/330 (41%), Positives = 189/330 (56%), Gaps = 21/330 (6%)
Query: 3 VSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRV 62
++LK R L L D+TPEEI L+ A LK +K G+ + ++GK +A+IF+K STRTR
Sbjct: 1 MNLKNRHFLKLLDFTPEEITAYLDLAAELKAAKKAGREIQRMKGKNIALIFEKTSTRTRC 60
Query: 63 SFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYA 122
+FEVA G YL Q+ E+I DTARVL R DAI R + + VE+LAKYA
Sbjct: 61 AFEVAARDQGAGVTYLEPSASQIGHKESIKDTARVLGRMYDAIEYRGFGQEVVEELAKYA 120
Query: 123 SVPVINGLSDFSHPCQALADYMTIWEKKG-TIKGVKVVYVGDGN-NVAHSLMIAGTKLGA 180
VPV NGL++ HP Q LAD +T+ E G + YVGD N+ +SL+I G KLG
Sbjct: 121 GVPVFNGLTNEFHPTQMLADALTMREHSGKPLNQTAFAYVGDARYNMGNSLLILGAKLGM 180
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
DV + P+ P E +I A A E+G L + +AVK+ D I+TDVW SMG+ E
Sbjct: 181 DVRIGAPQSLWPSEGIIAAAHAAAKETGAKITLTENAHEAVKNVDFIHTDVWVSMGEPKE 240
Query: 241 A-EERRKIFRPFQVNKDLV-KHAKPDYMFMHCLPAH-----------------RGEEVTD 281
+ER + + ++V +L+ P FMHCLPA G EVT+
Sbjct: 241 VWQERIDLLKDYRVTPELMAASGNPQVKFMHCLPAFHNRETKVGEWIYETFGLNGVEVTE 300
Query: 282 DVIDSPNSVVWDEAENRLHAQKAVLALLLG 311
++ +SP S+V+D+AENR+H KAV+ LG
Sbjct: 301 EIFESPASIVFDQAENRMHTIKAVMVAALG 330
>sp|Q00291|OTC_ASPTE ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OTCASE) (ORNITHINE
TRANSCARBAMYLASE) >gi|1054631|emb|CAA91554.1| (Z67741)
ornithine carbamoyltransferase [Aspergillus terreus]
Length = 361
Score = 233 bits (589), Expect = 2e-60
Identities = 141/317 (44%), Positives = 191/317 (59%), Gaps = 20/317 (6%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGK-PHRL---LEGKTLAMIFQKPSTRTRVS 63
R LL + D TP E T++ A K K G P L L GKT+AM+F K STRTR+S
Sbjct: 36 RHLLSIADLTPTEFTTLVRNASSHKHSIKSGSIPTNLQGSLAGKTVAMMFSKRSTRTRIS 95
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
E A LGGH ++L D+QL E++ DTA V+S V AI+ARV H +V DLAK+++
Sbjct: 96 TEGATVQLGGHPMFLGKDDIQLGVNESLYDTAVVVSSMVSAIVARVGKHAEVADLAKHST 155
Query: 124 VPVINGLSDFSHPCQALADYMTIWE---------KKGTIKGVKVVYVGDGNNVAHSLMIA 174
VPVIN L D HP QA+AD+ TI+E ++G+K+ +VGD NNV + I+
Sbjct: 156 VPVINALCDSFHPLQAIADFQTIYETFTPKAHHLSSLGLEGLKIAWVGDANNVLFDMAIS 215
Query: 175 GTKLGADVVVATPEGYE---PDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDV 231
K+G D+ VATP+GYE ++I+ A + A G + + P +AVK AD++ TD
Sbjct: 216 AAKMGVDLAVATPKGYEIPASMRELIQEAGKGVANPGKLIQ-TNVPEEAVKKADILVTDT 274
Query: 232 WASMGQEAEAEERRKIFRPFQVNKDLVKH--AKPDYMFMHCLPAHRGEEVTDDVIDSPNS 289
W SMGQE E+ +R K F FQ+ +L K A ++ FMHCLP H EEV+D+V S S
Sbjct: 275 WVSMGQEEESLKRMKAFEGFQITSELAKRGGANENWKFMHCLPRH-PEEVSDEVFYSNRS 333
Query: 290 VVWDEAENRLHAQKAVL 306
+V+ EAENRL A + L
Sbjct: 334 LVFPEAENRLWAAISAL 350
>gb|AAF44121.1|AF241726_1 (AF241726) ornithine transcarbamylase [Homo sapiens]
Length = 254
Score = 233 bits (589), Expect = 2e-60
Identities = 117/242 (48%), Positives = 159/242 (65%), Gaps = 1/242 (0%)
Query: 69 AHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVIN 128
A LGGH +L QD+ L E++ DTARVLS DA++ARVY D++ LAK AS+P+IN
Sbjct: 2 ALLGGHPCFLTTQDIHLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIIN 61
Query: 129 GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVVATPE 188
GLSD HP Q LADY+T+ E ++KG+ + ++GDGNN+ HS+M++ K G + ATP+
Sbjct: 62 GLSDLYHPIQILADYLTLQEHYSSLKGLTLSWIGDGNNILHSIMMSAAKFGMHLQAATPK 121
Query: 189 GYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRKIF 248
GYEPD V K AEQ A E+G L +DP++A +V+ TD W SMGQE E ++R + F
Sbjct: 122 GYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEKKKRLQAF 181
Query: 249 RPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVLAL 308
+ +QV K A D+ F+HCLP + EEV D+V SP S+V+ EAENR AV+
Sbjct: 182 QGYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVS 240
Query: 309 LL 310
LL
Sbjct: 241 LL 242
>sp|P14995|OTC_PACTA ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OTCASE) (ORNITHINE
TRANSCARBAMYLASE) >gi|279490|pir||OWCKPT ornithine
carbamoyltransferase (EC 2.1.3.3) precursor - yeast
(Pachysolen tannophilus) >gi|3267|emb|CAA33458.1|
(X15412) ornithine carbamoyltransferase preprotein
[Pachysolen tannophilus]
Length = 347
Score = 232 bits (585), Expect = 5e-60
Identities = 128/307 (41%), Positives = 195/307 (62%), Gaps = 7/307 (2%)
Query: 6 KGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRL--LEGKTLAMIFQKPSTRTRVS 63
K R L+ + + + +E+ +++ A K + G + L GKT+++IF K STRTRVS
Sbjct: 31 KPRHLVSMLELSIKELESLVNRAAYHKQQIRSGLVNTTQPLSGKTVSLIFNKRSTRTRVS 90
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
E A A+LGG ++L D+QL E++ DT +++S +I ARV H D++++ KY+S
Sbjct: 91 SEGAAAYLGGCPMFLGKDDIQLGVNESLHDTTKIISSMTSSIFARVNKHSDIQEMCKYSS 150
Query: 124 VPVINGLSDFSHPCQALADYMTIWEKKG-TIKGVKVVYVGDGNNVAHSLMIAGTKLGADV 182
VP+IN L D HP QA+ D +TI E G T KG+K+ ++GD NNV + L IA K G DV
Sbjct: 151 VPIINALCDTFHPLQAITDILTIKESFGNTTKGLKLAWIGDVNNVINDLCIAALKSGIDV 210
Query: 183 VVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAE 242
+A P G + +E ++ A++ +AE+G + ++ +DP++A+ A+VI TD W SMGQE E
Sbjct: 211 SIAVPSGLKFEELILSGAKEISAENGTTLKITNDPLEAINGANVIVTDTWISMGQEDERL 270
Query: 243 ERRKIFRPFQVNKDLVKHAK--PDYMFMHCLPAHRGEEVTDDVI-DSPNSVVWDEAENRL 299
++ K F FQ+ K+++ K ++ FMHCLP H EEV D+V D S+V++E ENRL
Sbjct: 271 QKLKQFEGFQITKEMISKGKAAENWKFMHCLPRH-PEEVHDEVFYDEERSLVFEEGENRL 329
Query: 300 HAQKAVL 306
+A AVL
Sbjct: 330 YAAIAVL 336
>pir||T49353 probable ornithine carbamoyltransferase precursor [imported] -
Neurospora crassa >gi|7800797|emb|CAB91256.1| (AL355927)
probable ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR
[Neurospora crassa]
Length = 363
Score = 231 bits (583), Expect = 8e-60
Identities = 142/323 (43%), Positives = 189/323 (57%), Gaps = 26/323 (8%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKI------GKPHRLLEGK----TLAMIFQKPS 57
R LL + +P E ++ A K K G+ R L+GK T+AM+F K S
Sbjct: 32 RHLLSISQLSPAEFSKLVLNASAYKQATKAAFAAGPGQVPRTLDGKLKGRTVAMMFSKRS 91
Query: 58 TRTRVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVED 117
TRTRVS E A+A +GGH ++L D+QL E++ DT++V+S ++ARV H DV D
Sbjct: 92 TRTRVSTEAAVALMGGHPMFLGKDDIQLGVNESLYDTSKVISSMTSCMVARVGPHSDVAD 151
Query: 118 LAKYASVPVINGLSDFSHPCQALADYMTIWEKKGT---------IKGVKVVYVGDGNNVA 168
LA+ +SVPVIN LSD HP QA+AD+ TI E T ++G+KV +VGD NNV
Sbjct: 152 LARDSSVPVINALSDDFHPLQAIADFQTIHEAFATKPAHEASLGLEGMKVAWVGDSNNVL 211
Query: 169 HSLMIAGTKLGADVVVATPEGYE-PD--EKVIKWAEQNAAESGGSFELLHDPVKAVKDAD 225
+ A LG D+ VA+P GY PD +++I + A+ G E P +AVKDAD
Sbjct: 212 FDMATACVMLGVDIAVASPAGYGIPDRMKQIILSVAEGVAKPGKLIETT-VPEEAVKDAD 270
Query: 226 VIYTDVWASMGQEAEAEERRKIFRPFQVNKDLVKH--AKPDYMFMHCLPAHRGEEVTDDV 283
++ TD W SMGQEAE + R K F FQ+ +L K AKP + FMHCLP H EEV D+V
Sbjct: 271 ILVTDTWVSMGQEAETQRRLKAFAGFQITNELAKRGGAKPGWKFMHCLPRH-PEEVDDEV 329
Query: 284 IDSPNSVVWDEAENRLHAQKAVL 306
P S+V+ EAENRL A + L
Sbjct: 330 FYGPQSLVFPEAENRLWAAVSAL 352
>sp|P21302|OTCC_NEIGO ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC (OTCASE)
>gi|279493|pir||OWNHG ornithine carbamoyltransferase (EC
2.1.3.3) - Neisseria gonorrhoeae
>gi|150241|gb|AAA25446.1| (M34930) ornithine
transcarbamoylase (argF) (EC 2.1.3.3) [Neisseria
gonorrhoeae]
Length = 331
Score = 230 bits (580), Expect = 2e-59
Identities = 137/330 (41%), Positives = 186/330 (55%), Gaps = 21/330 (6%)
Query: 3 VSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRV 62
++LK R L L D+TPEEI L+ A LK +K G+ + ++GK +A+IF+K STRTR
Sbjct: 1 MNLKNRHFLKLLDFTPEEITAYLDLAAELKDAKKAGREIQRMKGKNIALIFEKTSTRTRC 60
Query: 63 SFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYA 122
+FEVA G YL Q+ E+I DTARVL R DAI R + + VE+LAKYA
Sbjct: 61 AFEVAARDQGADRTYLEPSASQIGHKESIKDTARVLGRMYDAIEYRGFAQETVEELAKYA 120
Query: 123 SVPVINGLSDFSHPCQALADYMTIWEKKG-TIKGVKVVYVGDGN-NVAHSLMIAGTKLGA 180
VPV NGL++ HP Q LAD +T+ E G + YVGD N+ +SL+I G KLG
Sbjct: 121 GVPVFNGLTNEFHPTQMLADALTMREHSGKPLNQTAFAYVGDARYNMGNSLLILGAKLGM 180
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
DV + P+ P E +I A A E+G L + +AVK I+TDVW SMG+ E
Sbjct: 181 DVRIGAPQSLWPSEGIIAAAHAAAKETGAKITLTENAHEAVKGVGFIHTDVWVSMGEPKE 240
Query: 241 A-EERRKIFRPFQVNKDLV-KHAKPDYMFMHCLPAH-----------------RGEEVTD 281
+ER + + ++V +L+ P FMHCLPA G EVT+
Sbjct: 241 VWQERIDLLKDYRVTPELMAASGNPQVKFMHCLPAFHNRETKVGEWIYETFGLNGVEVTE 300
Query: 282 DVIDSPNSVVWDEAENRLHAQKAVLALLLG 311
+V +SP +V+D+AENR+H KAV+ LG
Sbjct: 301 EVFESPAGIVFDQAENRMHTIKAVMVAALG 330
>sp|Q46169|OTCC_CLOPE ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC (OTCASE)
>gi|1321787|emb|CAA66365.1| (X97768) ornithine carbamoyl
transferase [Clostridium perfringens]
Length = 331
Score = 230 bits (580), Expect = 2e-59
Identities = 133/332 (40%), Positives = 196/332 (58%), Gaps = 23/332 (6%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
M V+LKGR L L+D+TP EI +L+ + LK ++ G L+GK + ++F+K STRT
Sbjct: 1 MAVNLKGRSFLTLKDFTPAEIRYLLDLSHDLKAKKRAGILGDSLKGKNVVLLFEKTSTRT 60
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
R +FE A G H +L + Q+ + E+I DTA+VL R D I R + VE+LAK
Sbjct: 61 RCAFECGAAEEGAHVTFLT--NSQMGKKESIEDTAKVLGRMYDGIEFRGFKQSTVEELAK 118
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGT-IKGVKVVYVGDG-NNVAHSLMIAGTKL 178
+A VPV NGL+D HP Q LAD++TI E + +K+V+ G NN++++LM K+
Sbjct: 119 HAGVPVWNGLTDADHPTQILADFLTIEEHAHKPLSAIKLVFTGHTRNNMSYALMYGAAKM 178
Query: 179 GADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQ- 237
G V P+ +PDE ++K ++ + E+G + E + +AVK ADVIYTD+W SMG+
Sbjct: 179 GMHFVALGPDSLKPDEDILKEMQEYSKETGATIEFSSNVDEAVKGADVIYTDIWVSMGED 238
Query: 238 EAEAEERRKIFRPFQVNKDLV-KHAKPDYMFMHCLPAHRGE-----------------EV 279
E+ ER K+ P++V ++++ K + +FMHCLP+ E EV
Sbjct: 239 ESLYPERVKLLTPYKVTREMMNKTGNKNTLFMHCLPSFHDEDTEVCKDRWIDLGLDIREV 298
Query: 280 TDDVIDSPNSVVWDEAENRLHAQKAVLALLLG 311
D+V S NSVV+DEAENR+H KAV+ G
Sbjct: 299 EDEVFRSKNSVVFDEAENRMHTIKAVMVATAG 330
>gi|6322373 Ornithine carbamoyltransferase; Arg3p [Saccharomyces cerevisiae]
>gi|129280|sp|P05150|OTC_YEAST ORNITHINE
CARBAMOYLTRANSFERASE (OTCASE) (ORNITHINE
TRANSCARBAMYLASE) >gi|171075|gb|AAA34432.1| (M11946)
ornithine carbamoyltransferase (EC 2.1.3.3)
[Saccharomyces cerevisiae] >gi|171077|gb|AAA34433.1|
(M28301) ornithine carbamoyltransferase [Saccharomyces
cerevisiae]
Length = 338
Score = 228 bits (576), Expect = 5e-59
Identities = 125/318 (39%), Positives = 189/318 (59%), Gaps = 16/318 (5%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKP------HRLLEGKTLAMIFQKPSTRTR 61
R L+ ++D + EE +++ A+ K K K H L G+T+A+IF K STRTR
Sbjct: 12 RHLISIKDLSDEEFRILVQRAQHFKNVFKANKTNDFQSNHLKLLGRTIALIFTKRSTRTR 71
Query: 62 VSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKY 121
+S E A G ++L +D+QL E+ DT +V+S V I ARV H+D+ K
Sbjct: 72 ISTEGAATFFGAQPMFLGKEDIQLGVNESFYDTTKVVSSMVSCIFARVNKHEDILAFCKD 131
Query: 122 ASVPVINGLSDFSHPCQALADYMTIWEK---------KGTIKGVKVVYVGDGNNVAHSLM 172
+SVP+IN L D HP QA+ D +TI E KG +K+ ++GD NNV + +
Sbjct: 132 SSVPIINSLCDKFHPLQAICDLLTIIENFNISLDEVNKGINSKLKMAWIGDANNVINDMC 191
Query: 173 IAGTKLGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVW 232
IA K G V ++TP G E D ++ A++ A +G +FEL HD +KA +A+++ TD +
Sbjct: 192 IACLKFGISVSISTPPGIEMDSDIVDEAKKVAERNGATFELTHDSLKASTNANILVTDTF 251
Query: 233 ASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVW 292
SMG+E + + K F+ FQ+N++LV A P+Y FMHCLP H+ EEV+DDV +S+V+
Sbjct: 252 VSMGEEFAKQAKLKQFKGFQINQELVSVADPNYKFMHCLPRHQ-EEVSDDVFYGEHSIVF 310
Query: 293 DEAENRLHAQKAVLALLL 310
+EAENRL+A + + + +
Sbjct: 311 EEAENRLYAAMSAIDIFV 328
>pir||OWBY ornithine carbamoyltransferase (EC 2.1.3.3) - yeast (Saccharomyces
cerevisiae) >gi|929866|emb|CAA58480.1| (X83502) ARG3
(J0924) [Saccharomyces cerevisiae]
>gi|1008256|emb|CAA89381.1| (Z49363) ORF YJL088w
[Saccharomyces cerevisiae]
Length = 440
Score = 228 bits (576), Expect = 5e-59
Identities = 125/318 (39%), Positives = 189/318 (59%), Gaps = 16/318 (5%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKP------HRLLEGKTLAMIFQKPSTRTR 61
R L+ ++D + EE +++ A+ K K K H L G+T+A+IF K STRTR
Sbjct: 114 RHLISIKDLSDEEFRILVQRAQHFKNVFKANKTNDFQSNHLKLLGRTIALIFTKRSTRTR 173
Query: 62 VSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKY 121
+S E A G ++L +D+QL E+ DT +V+S V I ARV H+D+ K
Sbjct: 174 ISTEGAATFFGAQPMFLGKEDIQLGVNESFYDTTKVVSSMVSCIFARVNKHEDILAFCKD 233
Query: 122 ASVPVINGLSDFSHPCQALADYMTIWEK---------KGTIKGVKVVYVGDGNNVAHSLM 172
+SVP+IN L D HP QA+ D +TI E KG +K+ ++GD NNV + +
Sbjct: 234 SSVPIINSLCDKFHPLQAICDLLTIIENFNISLDEVNKGINSKLKMAWIGDANNVINDMC 293
Query: 173 IAGTKLGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVW 232
IA K G V ++TP G E D ++ A++ A +G +FEL HD +KA +A+++ TD +
Sbjct: 294 IACLKFGISVSISTPPGIEMDSDIVDEAKKVAERNGATFELTHDSLKASTNANILVTDTF 353
Query: 233 ASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVW 292
SMG+E + + K F+ FQ+N++LV A P+Y FMHCLP H+ EEV+DDV +S+V+
Sbjct: 354 VSMGEEFAKQAKLKQFKGFQINQELVSVADPNYKFMHCLPRHQ-EEVSDDVFYGEHSIVF 412
Query: 293 DEAENRLHAQKAVLALLL 310
+EAENRL+A + + + +
Sbjct: 413 EEAENRLYAAMSAIDIFV 430
>gb|AAD01405.1| (AF007428) ornithine carbamoyltransferase homolog [Haemophilus
paragallinarum]
Length = 334
Score = 228 bits (575), Expect = 7e-59
Identities = 131/333 (39%), Positives = 191/333 (57%), Gaps = 23/333 (6%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
M+ +LK R LL L +TP+EI +L+ AK LK + G L+GK +A+IF+K STRT
Sbjct: 1 MLFNLKNRHLLSLVHHTPQEIQFLLQLAKELKQAKYTGTEQPRLKGKNIALIFEKTSTRT 60
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
R SFEVA G + Y++ Q+ E++ DTARVL R DAI R + V +LA+
Sbjct: 61 RCSFEVAAYDQGANVTYIDPNSSQIGHKESMKDTARVLGRMYDAIEYRGFKQAVVNELAE 120
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKG-TIKGVKVVYVGDG-NNVAHSLMIAGTKL 178
YA VPV NGL+D HP Q LAD +T+ E + + VY+GD NN+ +SL++ G KL
Sbjct: 121 YAGVPVFNGLTDEFHPTQMLADVLTMMEHSDKPLSDIIYVYIGDARNNMGNSLLLIGAKL 180
Query: 179 GADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQE 238
G DV + P+ +P+ +++ ++ A ++G + D AVK D ++TDVW SMG+
Sbjct: 181 GMDVRICAPKALQPEAELVAMCQEFAQQTGARITITEDVELAVKGVDFVHTDVWVSMGEP 240
Query: 239 AEA-EERRKIFRPFQVNKDLVKHA-KPDYMFMHCLPAH-------------------RGE 277
E+ ER + P+QV L++ + P FMHCLPA G
Sbjct: 241 LESWGERINLLLPYQVTPALMQRSGNPKVKFMHCLPAFHNCETEVGKKIAEKYPHLANGI 300
Query: 278 EVTDDVIDSPNSVVWDEAENRLHAQKAVLALLL 310
EVT++V +SP ++ +D+AENR+H KAV+ L
Sbjct: 301 EVTEEVFESPMNIAFDQAENRMHTIKAVMVASL 333
>sp|P08308|OTCC_PSEAE ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC (OTCASE)
>gi|279494|pir||OWPSCA ornithine carbamoyltransferase
(EC 2.1.3.3), catabolic - Pseudomonas aeruginosa
>gi|11350695|pir||C82999 ornithine carbamoyltransferase,
catabolic PA5172 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|45288|emb|CAA29124.1| (X05637) arcB
(AA 1-336) [Pseudomonas aeruginosa]
>gi|9951475|gb|AAG08557.1|AE004930_3 (AE004930)
ornithine carbamoyltransferase, catabolic [Pseudomonas
aeruginosa]
Length = 336
Score = 225 bits (567), Expect = 6e-58
Identities = 130/336 (38%), Positives = 192/336 (56%), Gaps = 23/336 (6%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
M ++ R+LL L ++ E+ +L+ ++ LK + G + L+ K +A+IF+K STRT
Sbjct: 1 MAFNMHNRNLLSLMHHSTRELRYLLDLSRDLKRAKYTGTEQQHLKRKNIALIFEKTSTRT 60
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
R +FEVA G + Y++ Q+ E++ DTARVL R DAI R + + VE+LAK
Sbjct: 61 RCAFEVAAYDQGANVTYIDPNSSQIGHKESMKDTARVLGRMYDAIEYRGFKQEIVEELAK 120
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKG-TIKGVKVVYVGDG-NNVAHSLMIAGTKL 178
+A VPV NGL+D HP Q LAD +T+ E + + Y+GD NN+ +SL++ G KL
Sbjct: 121 FAGVPVFNGLTDEYHPTQMLADVLTMREHSDKPLHDISYAYLGDARNNMGNSLLLIGAKL 180
Query: 179 GADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQE 238
G DV +A P+ P ++ + ++ A ESG L DP +AVK D ++TDVW SMG+
Sbjct: 181 GMDVRIAAPKALWPHDEFVAQCKKFAEESGAKLTLTEDPKEAVKGVDFVHTDVWVSMGEP 240
Query: 239 AEA-EERRKIFRPFQVNKDLVK-HAKPDYMFMHCLPAH-------------------RGE 277
EA ER K P+QVN +++K P FMHCLPA G
Sbjct: 241 VEAWGERIKELLPYQVNMEIMKATGNPRAKFMHCLPAFHNSETKVGKQIAEQYPNLANGI 300
Query: 278 EVTDDVIDSPNSVVWDEAENRLHAQKAVLALLLGGV 313
EVT+DV +SP ++ +++AENR+H KA+L L +
Sbjct: 301 EVTEDVFESPYNIAFEQAENRMHTIKAILVSTLADI 336
>sp|P44770|OTCC_HAEIN ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC (OTCASE)
>gi|1075091|pir||H64079 ornithine carbamoyltransferase
(EC 2.1.3.3) - Haemophilus influenzae (strain Rd KW20)
>gi|1573585|gb|AAC22253.1| (U32741) ornithine
carbamoyltransferase (arcB) [Haemophilus influenzae Rd]
Length = 334
Score = 223 bits (562), Expect = 2e-57
Identities = 131/333 (39%), Positives = 187/333 (55%), Gaps = 23/333 (6%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
M ++K R LL L +T EI +L+ ++ LK + G + L+GK +A+IF+K STRT
Sbjct: 1 MAFNMKNRHLLSLVHHTEREIKYLLDLSRDLKRAKYAGTEQQKLKGKNIALIFEKTSTRT 60
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
R +FEVA G Y++ Q+ E++ DTARVL R D I R + V++LA
Sbjct: 61 RCAFEVAAYDQGAQVTYIDPNSSQIGHKESMKDTARVLGRMYDGIEYRGFKQSIVQELAD 120
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEK-KGTIKGVKVVYVGDG-NNVAHSLMIAGTKL 178
YA VPV NGL+D HP Q LAD +T+ E + + VY+GD NN+ +SL++ G KL
Sbjct: 121 YAGVPVFNGLTDEFHPTQMLADVLTMIEHCDKPLSEISYVYIGDARNNMGNSLLLIGAKL 180
Query: 179 GADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQE 238
G DV + P+ P+ +++ E+ A ESG + D KAVK D I+TDVW SMG+
Sbjct: 181 GMDVRICGPKALLPEANLVEMCEKFAKESGARITVTEDIDKAVKGVDFIHTDVWVSMGEP 240
Query: 239 AEA-EERRKIFRPFQVNKDLVKH-AKPDYMFMHCLPAH-------------------RGE 277
E ER K+ P+QV +L+K P FMHCLPA G
Sbjct: 241 LETWGERIKLLLPYQVTPELMKRTGNPKVKFMHCLPAFHNSETKVGRQIAEKYPELANGI 300
Query: 278 EVTDDVIDSPNSVVWDEAENRLHAQKAVLALLL 310
EVT++V +SP ++ +++AENR+H KAV+ L
Sbjct: 301 EVTEEVFESPMNIAFEQAENRMHTIKAVMVASL 333
>pdb|1ORT|A Chain A, Ornithine Transcarbamoylase From Pseudomonas Aeruginosa
>gi|1943015|pdb|1ORT|B Chain B, Ornithine
Transcarbamoylase From Pseudomonas Aeruginosa
>gi|1943016|pdb|1ORT|C Chain C, Ornithine
Transcarbamoylase From Pseudomonas Aeruginosa
>gi|1943017|pdb|1ORT|D Chain D, Ornithine
Transcarbamoylase From Pseudomonas Aeruginosa
>gi|1943018|pdb|1ORT|E Chain E, Ornithine
Transcarbamoylase From Pseudomonas Aeruginosa
>gi|1943019|pdb|1ORT|F Chain F, Ornithine
Transcarbamoylase From Pseudomonas Aeruginosa
>gi|1943020|pdb|1ORT|G Chain G, Ornithine
Transcarbamoylase From Pseudomonas Aeruginosa
>gi|1943021|pdb|1ORT|H Chain H, Ornithine
Transcarbamoylase From Pseudomonas Aeruginosa
>gi|1943022|pdb|1ORT|I Chain I, Ornithine
Transcarbamoylase From Pseudomonas Aeruginosa
>gi|1943023|pdb|1ORT|J Chain J, Ornithine
Transcarbamoylase From Pseudomonas Aeruginosa
>gi|1943024|pdb|1ORT|K Chain K, Ornithine
Transcarbamoylase From Pseudomonas Aeruginosa
>gi|1943025|pdb|1ORT|L Chain L, Ornithine
Transcarbamoylase From Pseudomonas Aeruginosa
Length = 335
Score = 223 bits (562), Expect = 2e-57
Identities = 129/333 (38%), Positives = 191/333 (56%), Gaps = 23/333 (6%)
Query: 4 SLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVS 63
++ R+LL L ++ E+ +L+ ++ LK + G + L+ K +A+IF+K STRTR +
Sbjct: 3 NMHNRNLLSLMHHSTRELRYLLDLSRDLKRAKYTGTEQQHLKRKNIALIFEKTSTRTRCA 62
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
FEVA G + Y++ Q+ E++ DTARVL R DAI R + + VE+LAK+A
Sbjct: 63 FEVAAYDQGANVTYIDPNSSQIGHKESMKDTARVLGRMYDAIGYRGFKQEIVEELAKFAG 122
Query: 124 VPVINGLSDFSHPCQALADYMTIWEKKG-TIKGVKVVYVGDG-NNVAHSLMIAGTKLGAD 181
VPV NGL+D HP Q LAD +T+ E + + Y+GD NN+ +SL++ G KLG D
Sbjct: 123 VPVFNGLTDEYHPTQMLADVLTMREHSDKPLHDISYAYLGDARNNMGNSLLLIGAKLGMD 182
Query: 182 VVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA 241
V +A P+ P ++ + ++ A ESG L DP +AVK D ++TDVW SMG+ EA
Sbjct: 183 VRIAAPKALWPHDEFVAQCKKFAEESGAKLTLTEDPKEAVKGVDFVHTDVWVSMGEPVEA 242
Query: 242 -EERRKIFRPFQVNKDLVK-HAKPDYMFMHCLPAH-------------------RGEEVT 280
ER K P+QVN +++K P FMHCLPA G EVT
Sbjct: 243 WGERIKELLPYQVNMEIMKATGNPRAKFMHCLPAFHNSETKVGKQIAEQYPNLANGIEVT 302
Query: 281 DDVIDSPNSVVWDEAENRLHAQKAVLALLLGGV 313
+DV +SP ++ +++AENR+H KA+L L +
Sbjct: 303 EDVFESPYNIAFEQAENRMHTIKAILVSTLADI 335
>emb|CAB75986.1| (AJ272085) ornithine carbamoyltransferase [Staphylococcus aureus]
>gi|7106008|emb|CAB75987.1| (AJ272086) ornithine
carbamoyltransferase Otc6850 [Staphylococcus aureus]
Length = 333
Score = 220 bits (556), Expect = 1e-56
Identities = 130/329 (39%), Positives = 191/329 (57%), Gaps = 21/329 (6%)
Query: 4 SLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVS 63
+L+ R L L D++ +E+ +L ++ LK + IG +L+ K +A++F+K STRTR +
Sbjct: 3 NLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCA 62
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
FEVA G + YL Q+ + ET DTARVL D I R + + VE LA+Y+
Sbjct: 63 FEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSG 122
Query: 124 VPVINGLSDFSHPCQALADYMTIWE-KKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLGAD 181
VPV NGL+D HP Q LAD++T E K + YVGDG NNVA++LM +G +
Sbjct: 123 VPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMGMN 182
Query: 182 VVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA 241
+ P+ P ++++ + AAE+GG+ + D + VK +DVIYTDVW SMG+ E
Sbjct: 183 FHLVCPKELNPTDELLNRCKNIAAENGGNILITDDIDQGVKGSDVIYTDVWVSMGEPDEV 242
Query: 242 -EERRKIFRPFQVNKDLV-KHAKPDYMFMHCLPAH-----------------RGEEVTDD 282
+ER ++ +P+QVNK+++ K P+ +F HCLP+ R EVTD+
Sbjct: 243 WKERLELLKPYQVNKEMMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVTDE 302
Query: 283 VIDSPNSVVWDEAENRLHAQKAVLALLLG 311
V +S SVV+ EAENR+H KAV+ LG
Sbjct: 303 VFESKASVVFQEAENRMHTIKAVMVATLG 331
>sp|P04391|OTC1_ECOLI ORNITHINE CARBAMOYLTRANSFERASE CHAIN I (OTCASE-1)
>gi|66492|pir||OWECI ornithine carbamoyltransferase (EC
2.1.3.3) chain I - Escherichia coli
>gi|537095|gb|AAA97150.1| (U14003) ornithine
carbamoyltransferase [Escherichia coli]
>gi|1790703|gb|AAC77211.1| (AE000496) ornithine
carbamoyltransferase 1 [Escherichia coli K12]
Length = 334
Score = 219 bits (553), Expect = 3e-56
Identities = 132/326 (40%), Positives = 181/326 (55%), Gaps = 23/326 (7%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
+ L L D+TP E+ ++L+ A LK +K GK L GK +A+IF+K STRTR SFEVA
Sbjct: 7 KHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLTGKNIALIFEKDSTRTRCSFEVA 66
Query: 68 MAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVI 127
G YL Q+ E+I DTARVL R D I R Y + VE LA+YASVPV
Sbjct: 67 AYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYASVPVW 126
Query: 128 NGLSDFSHPCQALADYMTIWE--KKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLGADVVV 184
NGL++ HP Q LAD +T+ E + +VY GD NN+ +S++ A G D+ +
Sbjct: 127 NGLTNEFHPTQLLADLLTMQEHLPGKAFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRL 186
Query: 185 ATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA-EE 243
P+ P+ ++ A ++GG+ L D K V+ AD IYTDVW SMG+ E E
Sbjct: 187 VAPQACWPEAALVTECRALAQQNGGNITLTEDVAKGVEGADFIYTDVWVSMGEAKEKWAE 246
Query: 244 RRKIFRPFQVNKDLVK-HAKPDYMFMHCLPA------------------HRGEEVTDDVI 284
R + R +QVN +++ P+ F+HCLPA H G EVTD+V
Sbjct: 247 RIALLREYQVNSKMMQLTGNPEVKFLHCLPAFHDDQTTLGKKMAEEFGLHGGMEVTDEVF 306
Query: 285 DSPNSVVWDEAENRLHAQKAVLALLL 310
+S S+V+D+AENR+H KAV+ L
Sbjct: 307 ESAASIVFDQAENRMHTIKAVMVATL 332
>pdb|1DUV|G Chain G, Crystal Structure Of E. Coli Ornithine Transcarbamoylase
Complexed With Ndelta-L-Ornithine-Diaminophosphinyl-N-
Sulphonic Acid (Psorn) >gi|9256874|pdb|1DUV|H Chain H,
Crystal Structure Of E. Coli Ornithine Transcarbamoylase
Complexed With Ndelta-L-Ornithine-Diaminophosphinyl-N-
Sulphonic Acid (Psorn) >gi|9256875|pdb|1DUV|I Chain I,
Crystal Structure Of E. Coli Ornithine Transcarbamoylase
Complexed With Ndelta-L-Ornithine-Diaminophosphinyl-N-
Sulphonic Acid (Psorn) >gi|3212448|pdb|1AKM|A Chain A,
Ornithine Transcarbamylase From Escherichia Coli
>gi|3212449|pdb|1AKM|B Chain B, Ornithine
Transcarbamylase From Escherichia Coli
>gi|3212450|pdb|1AKM|C Chain C, Ornithine
Transcarbamylase From Escherichia Coli
>gi|145344|gb|AAA23483.1| (J02842) ornithine
transcarbamoylase (argI; EC 2.1.3.3) [Escherichia coli]
Length = 333
Score = 219 bits (553), Expect = 3e-56
Identities = 132/326 (40%), Positives = 181/326 (55%), Gaps = 23/326 (7%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
+ L L D+TP E+ ++L+ A LK +K GK L GK +A+IF+K STRTR SFEVA
Sbjct: 6 KHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLTGKNIALIFEKDSTRTRCSFEVA 65
Query: 68 MAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVI 127
G YL Q+ E+I DTARVL R D I R Y + VE LA+YASVPV
Sbjct: 66 AYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYASVPVW 125
Query: 128 NGLSDFSHPCQALADYMTIWE--KKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLGADVVV 184
NGL++ HP Q LAD +T+ E + +VY GD NN+ +S++ A G D+ +
Sbjct: 126 NGLTNEFHPTQLLADLLTMQEHLPGKAFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRL 185
Query: 185 ATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA-EE 243
P+ P+ ++ A ++GG+ L D K V+ AD IYTDVW SMG+ E E
Sbjct: 186 VAPQACWPEAALVTECRALAQQNGGNITLTEDVAKGVEGADFIYTDVWVSMGEAKEKWAE 245
Query: 244 RRKIFRPFQVNKDLVK-HAKPDYMFMHCLPA------------------HRGEEVTDDVI 284
R + R +QVN +++ P+ F+HCLPA H G EVTD+V
Sbjct: 246 RIALLREYQVNSKMMQLTGNPEVKFLHCLPAFHDDQTTLGKKMAEEFGLHGGMEVTDEVF 305
Query: 285 DSPNSVVWDEAENRLHAQKAVLALLL 310
+S S+V+D+AENR+H KAV+ L
Sbjct: 306 ESAASIVFDQAENRMHTIKAVMVATL 331
>pdb|2OTC|A Chain A, Ornithine Transcarbamoylase Complexed With
N-(Phosphonacetyl)-L-Ornithine >gi|3318808|pdb|2OTC|B
Chain B, Ornithine Transcarbamoylase Complexed With
N-(Phosphonacetyl)-L-Ornithine >gi|3318809|pdb|2OTC|C
Chain C, Ornithine Transcarbamoylase Complexed With
N-(Phosphonacetyl)-L-Ornithine >gi|3318810|pdb|2OTC|D
Chain D, Ornithine Transcarbamoylase Complexed With
N-(Phosphonacetyl)-L-Ornithine >gi|3318811|pdb|2OTC|E
Chain E, Ornithine Transcarbamoylase Complexed With
N-(Phosphonacetyl)-L-Ornithine >gi|3318812|pdb|2OTC|F
Chain F, Ornithine Transcarbamoylase Complexed With
N-(Phosphonacetyl)-L-Ornithine >gi|3318813|pdb|2OTC|G
Chain G, Ornithine Transcarbamoylase Complexed With
N-(Phosphonacetyl)-L-Ornithine >gi|3318814|pdb|2OTC|H
Chain H, Ornithine Transcarbamoylase Complexed With
N-(Phosphonacetyl)-L-Ornithine >gi|3318815|pdb|2OTC|I
Chain I, Ornithine Transcarbamoylase Complexed With
N-(Phosphonacetyl)-L-Ornithine
Length = 333
Score = 217 bits (548), Expect = 1e-55
Identities = 131/326 (40%), Positives = 180/326 (55%), Gaps = 23/326 (7%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
+ L L D+TP E+ ++L+ A LK +K GK L GK +A+IF+K STRTR SFEVA
Sbjct: 6 KHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLTGKNIALIFEKDSTRTRCSFEVA 65
Query: 68 MAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVI 127
G YL Q+ E+I DTARVL R D I R Y + VE LA+YA VPV
Sbjct: 66 AYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYARVPVW 125
Query: 128 NGLSDFSHPCQALADYMTIWE--KKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLGADVVV 184
NGL++ HP Q LAD +T+ E + +VY GD NN+ +S++ A G D+ +
Sbjct: 126 NGLTNEFHPTQLLADLLTMQEHLPGKAFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRL 185
Query: 185 ATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA-EE 243
P+ P+ ++ A ++GG+ L D K V+ AD IYTDVW SMG+ E E
Sbjct: 186 VAPQACWPEAALVTECRALAQQNGGNITLTEDVAKGVEGADFIYTDVWVSMGEAKEKWAE 245
Query: 244 RRKIFRPFQVNKDLVK-HAKPDYMFMHCLPA------------------HRGEEVTDDVI 284
R + R +QVN +++ P+ F+HCLPA H G EVTD+V
Sbjct: 246 RIALLREYQVNSKMMQLTGNPEVKFLHCLPAFHDDQTTLGKKMAEEFGLHGGMEVTDEVF 305
Query: 285 DSPNSVVWDEAENRLHAQKAVLALLL 310
+S S+V+D+AENR+H KAV+ L
Sbjct: 306 ESAASIVFDQAENRMHTIKAVMVATL 331
>sp|P06960|OTC2_ECOLI ORNITHINE CARBAMOYLTRANSFERASE CHAIN F (OTCASE-2)
>gi|7427897|pir||OWECF ornithine carbamoyltransferase
(EC 2.1.3.3) chain F - Escherichia coli
>gi|1552842|gb|AAB08694.1| (U70214) OTCase [Escherichia
coli] >gi|1786469|gb|AAC73376.1| (AE000135) ornithine
carbamoyltransferase 2, chain F [Escherichia coli K12]
Length = 334
Score = 214 bits (539), Expect = 1e-54
Identities = 132/327 (40%), Positives = 177/327 (53%), Gaps = 23/327 (7%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
+ L L D+TP + ++L A LK +K GK + L GK +A+IF+K STRTR SFEVA
Sbjct: 7 KHFLKLLDFTPAQFTSLLTLAAQLKADKKNGKEVQKLTGKNIALIFEKDSTRTRCSFEVA 66
Query: 68 MAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVI 127
G YL Q+ E+I DTARVL R D I R + + VE LA+YA VPV
Sbjct: 67 AFDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGHGQEVVETLAQYAGVPVW 126
Query: 128 NGLSDFSHPCQALADYMTIWE--KKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLGADVVV 184
NGL++ HP Q LAD MT+ E + +VY GD NN+ +S++ A G D+ +
Sbjct: 127 NGLTNEFHPTQLLADLMTMQEHLPGKAFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRL 186
Query: 185 ATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA-EE 243
P+ P+E ++ A + GG L D VK AD IYTDVW SMG+ E E
Sbjct: 187 LAPKACWPEESLVAECSALAEKHGGKITLTEDVAAGVKGADFIYTDVWVSMGEAKEKWAE 246
Query: 244 RRKIFRPFQVNKDLVKHA-KPDYMFMHCLPA------------------HRGEEVTDDVI 284
R + R +QVN ++ P+ F+HCLPA H G EVTD+V
Sbjct: 247 RIALLRGYQVNAQMMALTDNPNVKFLHCLPAFHDDQTTLGKQMAKEFDLHGGMEVTDEVF 306
Query: 285 DSPNSVVWDEAENRLHAQKAVLALLLG 311
+S S+V+D+AENR+H KAV+ LG
Sbjct: 307 ESAASIVFDQAENRMHTIKAVMMATLG 333
>emb|CAA25329.1| (X00759) OTCase [Escherichia coli]
Length = 334
Score = 212 bits (534), Expect = 5e-54
Identities = 131/327 (40%), Positives = 176/327 (53%), Gaps = 23/327 (7%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
+ L L D+TP + ++L A LK +K GK + L GK +A+IF+K STRTR SFEVA
Sbjct: 7 KHFLKLLDFTPAQFTSLLTLAAQLKADKKNGKEVQKLTGKNIALIFEKDSTRTRCSFEVA 66
Query: 68 MAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVI 127
G YL Q+ E+I DTARVL R D I R + + VE LA+Y VPV
Sbjct: 67 AFDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGHGQEVVETLAQYPGVPVW 126
Query: 128 NGLSDFSHPCQALADYMTIWE--KKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLGADVVV 184
NGL++ HP Q LAD MT+ E + +VY GD NN+ +S++ A G D+ +
Sbjct: 127 NGLTNEFHPTQLLADLMTMQEHLPGKAFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRL 186
Query: 185 ATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA-EE 243
P+ P+E ++ A + GG L D VK AD IYTDVW SMG+ E E
Sbjct: 187 LAPKACWPEESLVAECSALAEKHGGKITLTEDVAAGVKGADFIYTDVWVSMGEAKEKWAE 246
Query: 244 RRKIFRPFQVNKDLVKHA-KPDYMFMHCLPA------------------HRGEEVTDDVI 284
R + R +QVN ++ P+ F+HCLPA H G EVTD+V
Sbjct: 247 RIALLRGYQVNAQMMALTDNPNVKFLHCLPAFHDDQTTLGKQMAKEFDLHGGMEVTDEVF 306
Query: 285 DSPNSVVWDEAENRLHAQKAVLALLLG 311
+S S+V+D+AENR+H KAV+ LG
Sbjct: 307 ESAASIVFDQAENRMHTIKAVMMATLG 333
>sp|P23752|OTCC_PSESH ORNITHINE CARBAMOYLTRANSFERASE, PHASEOLOTOXIN-INSENSITIVE,
CATABOLIC (OTCASE) >gi|279496|pir||OWPSY ornithine
carbamoyltransferase (EC 2.1.3.3) - Pseudomonas syringae
pv. phaseolicola >gi|151043|gb|AAA25722.1| (M94049)
ornithine carbamoyltransferase [Pseudomonas syringae]
>gi|2077926|dbj|BAA19878.1| (D86356) phaseolotoxin
resistant ornithine carbamoyltransferase [Pseudomonas
syringae]
Length = 327
Score = 205 bits (517), Expect = 5e-52
Identities = 119/319 (37%), Positives = 171/319 (53%), Gaps = 14/319 (4%)
Query: 2 VVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTR 61
+ SLK R+LL + ++ E+ +++ A K +K + L + IF KPS RT
Sbjct: 3 ITSLKNRNLLTMNEFNQSELSHLIDRAIECKRLKKDRIFNLGLNHLNICGIFLKPSGRTS 62
Query: 62 VSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKY 121
SF VA G H + A +++ E+I D ARV+ R D I R ++H+ E+LAK+
Sbjct: 63 TSFVVASYDEGAHFQFFPADNIRFGHKESIKDFARVVGRLFDGIAFRGFEHEVAEELAKH 122
Query: 122 ASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLGA 180
+ +PV N L+D HP Q LAD MT+ E+ G I+GV + YVGDG NN+ SL I K G
Sbjct: 123 SGIPVWNALTDTHHPTQVLADVMTVKEEFGRIEGVTIAYVGDGRNNMVTSLAIGALKFGY 182
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
++ + P P + V+ + E GS E+ + V ADVIYTDVW SMG+
Sbjct: 183 NLRIIAPNALHPTDAVLAGIYEQTPERNGSIEIFTEVAAGVHQADVIYTDVWISMGESVS 242
Query: 241 AEERRKIFRPFQV-NKDLVKHAKPDYMFMHCLPAHRG------------EEVTDDVIDSP 287
EER + +P++V K + K D +FMHCLPA EV D V + P
Sbjct: 243 VEERIALLKPYKVTEKMMALTGKADTIFMHCLPAFHDLDTEVARETPDLVEVEDSVFEGP 302
Query: 288 NSVVWDEAENRLHAQKAVL 306
S V+D+ ENR+H KA++
Sbjct: 303 QSRVFDQGENRMHTIKALM 321
>emb|CAA25037.1| (X00210) coding sequence argI gene [Escherichia coli]
Length = 334
Score = 205 bits (515), Expect = 8e-52
Identities = 125/326 (38%), Positives = 176/326 (53%), Gaps = 23/326 (7%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
+ L L D+TP E+ ++L+ A LK +K GK L GK +A+IF+K STRTR SFEVA
Sbjct: 7 KHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLTGKNIALIFEKDSTRTRCSFEVA 66
Query: 68 MAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVI 127
G YL Q+ E+I DTARVL R D I R Y + VE LA+Y SVPV
Sbjct: 67 AYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAQYRSVPVW 126
Query: 128 NGLSDFSHPCQALADYMTIWE--KKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLGADVVV 184
NGL++ HP Q + +T+ E + +VY GD NN+ +S++ A G D+ +
Sbjct: 127 NGLTNEFHPTQLIEYKLTMQEHLPGKAFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRL 186
Query: 185 ATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA-EE 243
P+ P+ ++ A ++GG+ L D K V+ AD IYTDVW SMG+ + E
Sbjct: 187 VAPQACWPEAALVTECRALAQQNGGNITLTEDVAKGVEGADFIYTDVWVSMGEAKQKWAE 246
Query: 244 RRKIFRPFQVNKDLVK-HAKPDYMFMHCLPA------------------HRGEEVTDDVI 284
R + +QVN +++ P+ F+HCLPA H G EVTD+V
Sbjct: 247 RIALLAEYQVNSKMMQLTGNPEVKFLHCLPAFHDDQTTLGKKMAEEFGLHGGMEVTDEVF 306
Query: 285 DSPNSVVWDEAENRLHAQKAVLALLL 310
+S S+V+ +AENR+H KAV+ L
Sbjct: 307 ESAASIVFGQAENRMHTIKAVMVATL 332
>gb|AAC28939.1| (AF069576) ornithine carbamoyltransferase [Giardia intestinalis]
Length = 327
Score = 205 bits (515), Expect = 8e-52
Identities = 130/321 (40%), Positives = 175/321 (54%), Gaps = 16/321 (4%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
R LL + P+E+ +++ A +K + K KTL F KPS RTRVS E A
Sbjct: 7 RHLLTISALCPKELAYLIDRALDMK--KNPAKYTARAANKTLLAFFAKPSLRTRVSLETA 64
Query: 68 MAHLGGHALYLN-AQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPV 126
M LGGHA+Y + + ET+ DTA V SR VD AR+ + + ++A++ASVP
Sbjct: 65 MTRLGGHAIYYELGANSNVGGKETVQDTAEVFSRMVDICTARLATKEMMREMAQHASVPC 124
Query: 127 INGLSDFSHPCQALADYMTIWEK-------KGTIKGVKVVYVGDG-NNVAHSLMIAGTKL 178
IN L DF HP Q + D+MTI EK KG+K Y GD NNV + LM L
Sbjct: 125 INALDDFGHPLQMVCDFMTIKEKFTAAGEFSNGFKGIKFAYCGDSMNNVTYDLMRGCALL 184
Query: 179 GADVVVATPE--GYEPDEKVIKWAEQNAAE--SGGSFELLHDPVKAVKDADVIYTDVWAS 234
G + V P+ ++P ++VI E+ A+ +GGS ++ HD K + DV+YTD W S
Sbjct: 185 GMECHVCCPDHKDFKPIKEVIDECEEIIAKHGTGGSIKIFHDCKKGCEGVDVVYTDSWMS 244
Query: 235 MGQEAEAEERR-KIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWD 293
E +E R K+ PFQV+ ++ +FM+CLPA RGEE T VID P SV +D
Sbjct: 245 YHITKEQKEARLKVLTPFQVDDAVMAVTSKRSIFMNCLPATRGEEQTASVIDGPKSVCYD 304
Query: 294 EAENRLHAQKAVLALLLGGVK 314
EA NRLH+ AVL L K
Sbjct: 305 EAGNRLHSAMAVLDFFLHDCK 325
>prf||1707278A Orn carbamoyltransferase [Pseudomonas syringae pv. phaseolicola]
Length = 327
Score = 204 bits (514), Expect = 1e-51
Identities = 119/319 (37%), Positives = 170/319 (52%), Gaps = 14/319 (4%)
Query: 2 VVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTR 61
+ SLK R+LL + + E+ +++ A K +K + L + IF KPS RT
Sbjct: 3 ITSLKNRNLLTMNFFNQSELSHLIDRAIECKRLKKDRIFNLGLNHLNICGIFLKPSGRTS 62
Query: 62 VSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKY 121
SF VA G H + A +++ E+I D ARV+ R D I R ++H+ E+LAK+
Sbjct: 63 TSFVVASYDEGAHFQFFPADNIRFGHKESIKDFARVVGRLFDGIAFRGFEHEVAEELAKH 122
Query: 122 ASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLGA 180
+ +PV N L+D HP Q LAD MT+ E+ G I+GV + YVGDG NN+ SL I K G
Sbjct: 123 SGIPVWNALTDTHHPTQVLADVMTVKEEFGRIEGVTIAYVGDGRNNMVTSLAIGALKFGY 182
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
++ + P P + V+ + E GS E+ + V ADVIYTDVW SMG+
Sbjct: 183 NIRIIAPNALHPTDAVLAGIYEQTPERNGSIEIFTEVAAGVHQADVIYTDVWISMGESVS 242
Query: 241 AEERRKIFRPFQV-NKDLVKHAKPDYMFMHCLPAHRG------------EEVTDDVIDSP 287
EER + +P++V K + K D +FMHCLPA EV D V + P
Sbjct: 243 VEERIALLKPYKVTEKMMALTGKADTIFMHCLPAFHDLDTEVARETPDLVEVEDSVFEGP 302
Query: 288 NSVVWDEAENRLHAQKAVL 306
S V+D+ ENR+H KA++
Sbjct: 303 QSRVFDQGENRMHTIKALM 321
>emb|CAA39136.1| (X55520) phaseolotoxin-insensitive ornithine carbamoyltransferase
[Pseudomonas syringae]
Length = 327
Score = 204 bits (514), Expect = 1e-51
Identities = 118/319 (36%), Positives = 171/319 (52%), Gaps = 14/319 (4%)
Query: 2 VVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTR 61
+ SLK R+LL + ++ E+ +++ A K +K + L + IF KPS RT
Sbjct: 3 ITSLKNRNLLTMNEFNQSELSHLIDRAIECKRLKKDRIFNLGLNHLNICGIFLKPSGRTS 62
Query: 62 VSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKY 121
SF VA G H + A +++ E+I D ARV+ R D I R ++H+ E+LAK+
Sbjct: 63 TSFVVASYDEGAHFQFFPADNIRFGHKESIKDFARVVGRLFDGIAFRGFEHEVAEELAKH 122
Query: 122 ASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLGA 180
+ +PV N L+D HP Q LAD MT+ E+ G I+GV + YVGDG NN+ SL I K G
Sbjct: 123 SGIPVWNALTDTHHPTQVLADVMTVKEEFGPIEGVTIAYVGDGRNNMVTSLAIGALKFGY 182
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
++ + P P + V+ + E GS E+ + V ADVIYTDVW SMG+
Sbjct: 183 NLRIIAPNALHPTDAVLAGIYEQTPERNGSIEIFTEVAAGVHQADVIYTDVWISMGESVS 242
Query: 241 AEERRKIFRPFQV-NKDLVKHAKPDYMFMHCLPAHRG------------EEVTDDVIDSP 287
EER + +P++V K + K D +FMHCLPA +V D V + P
Sbjct: 243 VEERIALLKPYKVTEKMMALTGKADTIFMHCLPAFHDLDTEVARETPDLVQVEDSVFEGP 302
Query: 288 NSVVWDEAENRLHAQKAVL 306
S V+D+ ENR+H KA++
Sbjct: 303 QSRVFDQGENRMHTIKALM 321
>sp|P78605|OTC_CORHI ORNITHINE CARBAMOYLTRANSFERASE PRECURSOR (OTCASE) (ORNITHINE
TRANSCARBAMYLASE) >gi|1799542|dbj|BAA05060.1| (D26061)
ornithine carbamoyltransferase [Coriolus hirsutus]
Length = 375
Score = 203 bits (510), Expect = 3e-51
Identities = 130/359 (36%), Positives = 182/359 (50%), Gaps = 49/359 (13%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKI----W-----------------QKIGK 39
M +S K L+ L D TP +I I+ + LK W K+
Sbjct: 1 MALSTKVPHLMTLADLTPGQIQRIITHSYHLKRTAQPWLAPQGRAGSGGKYSNAPHKLRM 60
Query: 40 PHRLLEGKTLAMIFQKPSTRTRVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLS 99
P + L K++A++F K STRTR+S E A LGG AL+L +D+QL ET+ D+ARV+
Sbjct: 61 PSQSLFSKSIALLFSKRSTRTRLSAETAALLLGGQALFLGREDIQLGVNETVPDSARVIG 120
Query: 100 RYVDAIMARVYDHKDVEDLAKYASVPVINGLSDFSHPCQALADYMTIWE----------- 148
I ARV DH ++E+LA+Y+ VPV+N LS HP Q LAD +T+ E
Sbjct: 121 GMCQGIFARVGDHSEIEELARYSPVPVLNALSSLWHPTQVLADILTLHEHAALFDPASAS 180
Query: 149 --------------KKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVVATPEGYEPDE 194
K G ++ + V YVGD NV H +++ +LG + VA+PE +
Sbjct: 181 PTPSAADAFSQKYTKLGEVRPLTVAYVGDSANVLHDMLVTYPRLGHQLRVASPENDKYRA 240
Query: 195 KVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRKIFRPFQVN 254
W + DP AVK AD++ TD W SMGQEAE +R K F +QV
Sbjct: 241 PKAVWDRVVELGCDKNIFWTADPRAAVKGADLVVTDTWISMGQEAEKAQRLKDFAGYQVT 300
Query: 255 KDLVKH--AKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVLALLLG 311
+ L + A PD+ FMHCLP + +EV D+V P S+V+ E++NR A+ LL G
Sbjct: 301 EALCREGGANPDWKFMHCLP-RKQDEVDDEVFYGPRSLVFQESDNRKWTIMALFDLLFG 358
>dbj|BAA05061.1| (D26062) ornithine carbamoyltransferase [Coriolus hirsutus]
Length = 375
Score = 202 bits (509), Expect = 4e-51
Identities = 130/359 (36%), Positives = 181/359 (50%), Gaps = 49/359 (13%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKI----W-----------------QKIGK 39
M +S K L+ L D TP +I I+ + LK W K+
Sbjct: 1 MALSTKVPHLMTLADLTPGQIQRIITHSYHLKRTAQPWLAPQGRAGSGGKYSNAPHKLRM 60
Query: 40 PHRLLEGKTLAMIFQKPSTRTRVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLS 99
P + L K++A++F K STRTR+S E A LGG AL+L +D+QL ET+ D+ARV+
Sbjct: 61 PSQSLFSKSIALLFSKRSTRTRLSAETAALLLGGQALFLGREDIQLGVNETVPDSARVIG 120
Query: 100 RYVDAIMARVYDHKDVEDLAKYASVPVINGLSDFSHPCQALADYMTIWE----------- 148
I ARV DH ++E+LA+Y+ VPV+N LS HP Q LAD +T+ E
Sbjct: 121 GMCQGIFARVGDHSEIEELARYSPVPVLNALSSLWHPTQVLADILTLHEHAALFDPASAS 180
Query: 149 --------------KKGTIKGVKVVYVGDGNNVAHSLMIAGTKLGADVVVATPEGYEPDE 194
K G ++ + V YVGD NV H +++ +LG + VA+PE
Sbjct: 181 PTPSAADAFSQKYTKLGEVRPLTVAYVGDSANVLHDMLVTYPRLGHQLRVASPENDRYRA 240
Query: 195 KVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRKIFRPFQVN 254
W + DP AVK AD++ TD W SMGQEAE +R K F +QV
Sbjct: 241 PKAVWDRVVELGCDKNIFWTADPRAAVKGADLVVTDTWISMGQEAEKAQRLKDFAGYQVT 300
Query: 255 KDLVKH--AKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVLALLLG 311
+ L + A PD+ FMHCLP + +EV D+V P S+V+ E++NR A+ LL G
Sbjct: 301 EALCREGGANPDWKFMHCLP-RKQDEVDDEVFYGPRSLVFQESDNRKWTIMALFDLLFG 358
>gi|11420218 similar to ornithine carbamoyltransferase (H. sapiens) [Homo
sapiens]
Length = 221
Score = 202 bits (509), Expect = 4e-51
Identities = 100/208 (48%), Positives = 138/208 (66%), Gaps = 1/208 (0%)
Query: 103 DAIMARVYDHKDVEDLAKYASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVG 162
DA++ARVY D++ LAK AS+P+INGLSD HP Q LADY+T+ E ++KG+ + ++G
Sbjct: 3 DAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQEHYSSLKGLTLSWIG 62
Query: 163 DGNNVAHSLMIAGTKLGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVK 222
DGNN+ HS+M++ K G + ATP+GYEPD V K AEQ A E+G L +DP++A
Sbjct: 63 DGNNILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAH 122
Query: 223 DADVIYTDVWASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDD 282
+V+ TD W SMGQE E ++R + F+ +QV K A D+ F+HCLP + EEV D+
Sbjct: 123 GGNVLITDTWISMGQEEEKKKRLQAFQGYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDE 181
Query: 283 VIDSPNSVVWDEAENRLHAQKAVLALLL 310
V SP S+V+ EAENR AV+ LL
Sbjct: 182 VFYSPRSLVFPEAENRKWTIMAVMVSLL 209
>sp|P57449|OTCA_BUCAI ORNITHINE CARBAMOYLTRANSFERASE, ANABOLIC (OTCASE)
>gi|10039038|dbj|BAB13072.1| (AP001119) ornithine
carbamoyltransferase chain F [Buchnera sp. APS]
Length = 338
Score = 199 bits (501), Expect = 3e-50
Identities = 120/326 (36%), Positives = 178/326 (53%), Gaps = 23/326 (7%)
Query: 4 SLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVS 63
+L RD L L D+T E+ I+ A+ LK ++K K +LL+ K +A+IF+K STRTR S
Sbjct: 3 NLYQRDCLRLLDFTSLELQNIITLAQKLKQYKKNNKEIQLLKKKNIALIFEKESTRTRCS 62
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
FEVA G H YL L E+I DTA++L R D I R + H +E LAK +
Sbjct: 63 FEVAAFDQGAHVTYLGPGSTHLGTKESIEDTAKILGRLYDGIQYRGHHHSTIEILAKNSK 122
Query: 124 VPVINGLSDFSHPCQALADYMTIWE--KKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLGA 180
VPV NGL++ HP Q LAD +TI E + +K YVGD NN+ +SL+ A + +G
Sbjct: 123 VPVWNGLTEKFHPTQLLADLLTIKEIFPERKFYEIKCAYVGDAHNNMGNSLLEAASLVGL 182
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
D+ + P+ P++ + K+ ++ G+ + + VK+ D IYTDVW SMG+ E
Sbjct: 183 DLRLVAPKECWPEKNIFKFCKEQMKNKKGNIICTENINEGVKNVDFIYTDVWVSMGESQE 242
Query: 241 AEERR-KIFRPFQVNKDLVKHA-KPDYMFMHCLPA------------------HRGEEVT 280
++R ++ +QVN ++K P +HCLPA G E+T
Sbjct: 243 VWKKRIELLSSYQVNSLMLKITNNPQVKVLHCLPALHDQKTCTVKSILKKYGFKNGMEIT 302
Query: 281 DDVIDSPNSVVWDEAENRLHAQKAVL 306
D+V +++++AENRLH KA+L
Sbjct: 303 DEVFQKNQKIIFEQAENRLHTIKAIL 328
>pir||S24720 ornithine carbamoyltransferase (EC 2.1.3.3) - Neisseria gonorrhoeae
(strain FA19) (fragment)
Length = 280
Score = 198 bits (497), Expect = 1e-49
Identities = 116/278 (41%), Positives = 157/278 (55%), Gaps = 21/278 (7%)
Query: 44 LEGKTLAMIFQKPSTRTRVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVD 103
++GK +A+IF+K STRTR +FEVA G A YL Q+ E+I DTARVL R D
Sbjct: 2 MKGKNIALIFEKTSTRTRCAFEVAARDQGAAATYLEPSASQIGHKESIKDTARVLGRMYD 61
Query: 104 AIMARVYDHKDVEDLAKYASVPVINGLSDFSHPCQALADYMTIWEKKG-TIKGVKVVYVG 162
AI R + + VE+LAKYA VPV NGL++ HP Q LAD +T+ E G + YVG
Sbjct: 62 AIEYRGFAQETVEELAKYAGVPVFNGLTNEFHPTQMLADALTMREHSGKPLNQTAFAYVG 121
Query: 163 DGN-NVAHSLMIAGTKLGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAV 221
D N+ +SL+I G KLG DV + P+ P E +I A A E+G L + +AV
Sbjct: 122 DARYNMGNSLLILGAKLGMDVRIGAPQSLWPSEGIIAAAHAAAKETGAKITLTENAHEAV 181
Query: 222 KDADVIYTDVWASMGQEAEA-EERRKIFRPFQVNKDLV-KHAKPDYMFMHCLPAH----- 274
K I+TDVW SMG+ E +ER + + ++V +L+ P FMHCLPA
Sbjct: 182 KGVGFIHTDVWVSMGEPKEVWQERIDLLKDYRVTPELMAASGNPQVKFMHCLPAFHNRET 241
Query: 275 ------------RGEEVTDDVIDSPNSVVWDEAENRLH 300
G EVT++V +SP +V+D+AENR+H
Sbjct: 242 KVGEWIYETFGLNGVEVTEEVFESPAGIVFDQAENRMH 279
>sp|Q01324|OTCC_NEILA ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC (OTCASE)
>gi|281743|pir||S24723 ornithine carbamoyltransferase
(EC 2.1.3.3) - Neisseria lactamica (NCTC 10617)
(fragment) >gi|44995|emb|CAA46083.1| (X64871) ornithine
carbamoyltransferase [Neisseria lactamica]
Length = 262
Score = 179 bits (450), Expect = 3e-44
Identities = 109/262 (41%), Positives = 144/262 (54%), Gaps = 21/262 (8%)
Query: 55 KPSTRTRVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKD 114
K STRTR +FEVA G YL + Q+ E+I DTARVL R DAI R + +
Sbjct: 1 KTSTRTRCAFEVAARDQGAGVTYLESSASQIGHKESIKDTARVLGRMYDAIEYRGFGQET 60
Query: 115 VEDLAKYASVPVINGLSDFSHPCQALADYMTIWEKKG-TIKGVKVVYVGDGN-NVAHSLM 172
VE+LAKYA VPV NGL++ HP Q LAD +T+ E G + YVGD N+ +SL+
Sbjct: 61 VEELAKYAGVPVFNGLTNEFHPTQMLADALTMREHGGKPLNQTSFAYVGDARYNMGNSLL 120
Query: 173 IAGTKLGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVW 232
I G KLG DV + PEG P E +I A A E+G L +P +AVK I+TDVW
Sbjct: 121 ILGAKLGMDVRIGAPEGLWPSEGIIAAANAVAEETGAKITLTANPQEAVKGVGFIHTDVW 180
Query: 233 ASMGQEAEA-EERRKIFRPFQVNKDLV-KHAKPDYMFMHCLPAH---------------- 274
SMG+ E +ER + + ++V +L+ P FMHCLPA
Sbjct: 181 VSMGEPKEIWQERIDLLKDYRVTSELMAASGNPQVKFMHCLPAFHNRETKIGEWIYETFG 240
Query: 275 -RGEEVTDDVIDSPNSVVWDEA 295
G EVT++V +SP +V+D+A
Sbjct: 241 LNGVEVTEEVFESPAGIVFDQA 262
>pir||S24734 ornithine carbamoyltransferase (EC 2.1.3.3) - Neisseria
meningitidis (fragment) >gi|45056|emb|CAA46077.1|
(X64865) ornithine carbamoyltransferase [Neisseria
meningitidis]
Length = 262
Score = 178 bits (447), Expect = 7e-44
Identities = 108/262 (41%), Positives = 144/262 (54%), Gaps = 21/262 (8%)
Query: 55 KPSTRTRVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKD 114
K STRTR +FEVA G YL Q+ E+I DTARVL R DAI R + +
Sbjct: 1 KTSTRTRCAFEVAARDQGAGVTYLEPSASQIGHKESIKDTARVLGRMYDAIEYRGFGQET 60
Query: 115 VEDLAKYASVPVINGLSDFSHPCQALADYMTIWEKKG-TIKGVKVVYVGDGN-NVAHSLM 172
VE+LAKYA VPV NGL++ HP Q LAD +T+ E G + YVGD N+ +SL+
Sbjct: 61 VEELAKYAGVPVFNGLTNEFHPTQMLADALTMREHSGKPLNQTAFAYVGDARYNMGNSLL 120
Query: 173 IAGTKLGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVW 232
I G KLG DV + P+ P E +I A A E+G L + +AVK+ D I+TDVW
Sbjct: 121 ILGAKLGMDVRIGAPQSLWPSEGIIAAAHAAAKETGAKITLTENAHEAVKNVDFIHTDVW 180
Query: 233 ASMGQEAEA-EERRKIFRPFQVNKDLV-KHAKPDYMFMHCLPAH---------------- 274
SMG+ E +ER + + ++V +L+ P FMHCLPA
Sbjct: 181 VSMGEPKEVWQERIDLLKDYRVTPELMAASGNPQVKFMHCLPAFHNRETKVGEWIYETFG 240
Query: 275 -RGEEVTDDVIDSPNSVVWDEA 295
G EVT++V +SP S+V+D+A
Sbjct: 241 LNGVEVTEEVFESPASIVFDQA 262
>sp|P75473|OTCC_MYCPN ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC (OTCASE)
>gi|2146484|pir||S73856 ornithine carbamoyltransferase
(EC 2.1.3.3) argI - Mycoplasma pneumoniae (strain ATCC
29342) >gi|1674226|gb|AAB96178.1| (AE000052) less
(fragment) [Mycoplasma pneumoniae]
Length = 273
Score = 172 bits (432), Expect = 4e-42
Identities = 107/271 (39%), Positives = 146/271 (53%), Gaps = 39/271 (14%)
Query: 77 YLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVINGLSDFSHP 136
Y+ + E+I DTA+VL D I R + DV+ L KY+ VPV NGL+D HP
Sbjct: 5 YIGPSGSNFGKKESIEDTAKVLGSMYDGIEFRGFKQSDVDALVKYSGVPVWNGLTDAEHP 64
Query: 137 CQALADYMTIWEKKGTIKGVKVVYVGD-GNNVAHSLMIAGTKLGADVVVATPE------- 188
Q LADYMTI E KG +KG K+V+ GD NNVA SLMI +G D+V+ P+
Sbjct: 65 TQMLADYMTIKELKGDLKGRKIVFAGDIKNNVARSLMIGAAFVGMDIVLVGPKAQHELVQ 124
Query: 189 ---GYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA-EER 244
GY ++V + + +GGS D ++A K+ADVIYTDVW S+G++ EER
Sbjct: 125 NGAGY---KEVFEQCQALFQLNGGSVSFSTDKLQAAKNADVIYTDVWLSLGEDFSLFEER 181
Query: 245 RKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGE------------------------EVT 280
+ FQV+ ++K AK D +F+HCLPA + EVT
Sbjct: 182 IQELGQFQVDMAMIKAAKSDVIFLHCLPAFHDDHTSFSLEIKQKLGKKYPVVKTGAMEVT 241
Query: 281 DDVIDSPNSVVWDEAENRLHAQKAVLALLLG 311
D V S +++ + +AENRLH KAV+ LG
Sbjct: 242 DTVFQSKHNMAFIQAENRLHTIKAVILATLG 272
>pir||F82737 ornithine carbamoyltransferase XF0998 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9105932|gb|AAF83808.1|AE003937_12 (AE003937)
ornithine carbamoyltransferase [Xylella fastidiosa]
Length = 336
Score = 171 bits (429), Expect = 9e-42
Identities = 122/336 (36%), Positives = 174/336 (51%), Gaps = 40/336 (11%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
+ L QD++ E+ +L A+ K K+G L+GK++A++F S RTR SFE+
Sbjct: 4 KHFLNTQDWSCSELNALLTQARAFK-HNKLGNG---LKGKSIALVFFNASMRTRSSFELG 59
Query: 68 MAHLGGHALYL----NAQDLQLRRG--------ETIADTARVLSRYVDAIMARV------ 109
LGGHA+ L +A ++ G E I + ARVL YVD I R
Sbjct: 60 AFQLGGHAIVLQPGKDAWPIEFDTGTVMEAETEEHICEVARVLGHYVDLIGVRAFPKFLD 119
Query: 110 --YDHKDV--EDLAKYASVPVINGLSDFSHPCQALADYMTIWEKKGT--IKGVKVVYVGD 163
YD +D+ AKY+ VPVIN + +HPCQ LA M + E GT ++G K V
Sbjct: 120 WTYDRQDIVLNGFAKYSPVPVIN-METITHPCQELAHIMALQEHFGTTDLRGKKYVLTWT 178
Query: 164 ------GNNVAHSLMIAGTKLGADVVVATPE-GYEPDEKVIKWAEQNAAESGGSFELLHD 216
VA+S + T+LG DV + P Y DE+ I WA+QN A++G +F++ HD
Sbjct: 179 YHPKPLNTAVANSALTIATRLGMDVTLLCPTPDYVLDERYIDWAQQNIADTGSTFQVSHD 238
Query: 217 PVKAVKDADVIYTDVWASM---GQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPA 273
A + ADVIY W ++ G A + R +R F V++ + + +F HCLP
Sbjct: 239 IDNAYRGADVIYAKSWGALPFFGNWAMEKPIRDQYRHFIVDEAKMALTN-NAVFSHCLPL 297
Query: 274 HRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVLALL 309
R + TD V+D PN + EA NRLH QKA++A L
Sbjct: 298 RRNVKATDAVMDGPNCIAIHEAGNRLHVQKAIMAAL 333
>emb|CAA66276.1| (X97684) ornithine carbamoyl transferase [Clostridium perfringens]
Length = 217
Score = 153 bits (384), Expect = 2e-36
Identities = 84/208 (40%), Positives = 128/208 (61%), Gaps = 4/208 (1%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
M V+LKGR L L+D+TP EI +L+ + LK ++ G L+GK + ++F+K STRT
Sbjct: 1 MAVNLKGRSFLTLKDFTPAEIRYLLDLSHDLKAKKRAGILGDSLKGKNVVLLFEKTSTRT 60
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK 120
R +FE A G H +L + Q+ + E+I DTA+VL R D I R + VE+LAK
Sbjct: 61 RCAFECGAAEEGAHVTFLT--NSQMGKKESIEDTAKVLGRMYDGIEFRGFKQSTVEELAK 118
Query: 121 YASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD-GNNVAHSLMIAGTKLG 179
+A VPV+NGL+D HP Q LAD++TI E + +K+V+ GD NN++++LM K+G
Sbjct: 119 HAGVPVVNGLTDADHPTQILADFLTI-EAHKPLSEIKLVFTGDTRNNMSYALMYGAAKMG 177
Query: 180 ADVVVATPEGYEPDEKVIKWAEQNAAES 207
V P+ +PDE ++K ++ + E+
Sbjct: 178 MHFVALGPDSLKPDEDILKEMQEYSKET 205
>emb|CAA60100.1| (X86157) ornithine carbamoyltransferase [Corynebacterium
glutamicum]
Length = 201
Score = 151 bits (378), Expect = 9e-36
Identities = 86/193 (44%), Positives = 119/193 (61%), Gaps = 11/193 (5%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEG-KTLAMIFQKPSTRTRVSFEV 66
R L D TP E +L A LK +P LEG K++A++F K STRTR SF+
Sbjct: 8 RHFLADDDLTPAEQAEVLTLAAKLKAAPFSERP---LEGPKSVAVLFDKTSTRTRFSFDA 64
Query: 67 AMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPV 126
+AHLGGHA+ +++ Q+ +GE++ DTA VLSRYV+AI+ R Y H + +A+ ++VP+
Sbjct: 65 GIAHLGGHAIVVDSGSSQMGKGESLQDTAAVLSRYVEAIVWRTYAHSNFHAMAETSTVPL 124
Query: 127 INGLSDFSHPCQALADYMTIWEK------KGTIKGVKVVYVGDG-NNVAHSLMIAGTKLG 179
+N LSD HPCQ LAD TI E +KG K VY+GDG NN+A+S MI G
Sbjct: 125 VNSLSDDLHPCQILADLQTIVENLSPEEGPAGLKGKKAVYLGDGDNNMANSYMIGFATAG 184
Query: 180 ADVVVATPEGYEP 192
D+ + PEG++P
Sbjct: 185 MDISIIAPEGFQP 197
>pir||A81238 aspartate carbamoyltransferase (EC 2.1.3.2) catalytic chain NMA0168
[imported] - Neisseria meningitidis (group B strain
MD58, group A strain Z2491) >gi|7225321|gb|AAF40565.1|
(AE002369) aspartate carbamoyltransferase, catalytic
subunit [Neisseria meningitidis MC58]
>gi|7378939|emb|CAB83482.1| (AL162752) aspartate
carbamoyltransferase catalytic chain [Neisseria
meningitidis Z2491]
Length = 306
Score = 139 bits (347), Expect = 4e-32
Identities = 94/305 (30%), Positives = 162/305 (52%), Gaps = 16/305 (5%)
Query: 10 LLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAMA 69
++ + D + E++ +L+TA LK + LLEGK + F +PSTRTR+SFE A+
Sbjct: 10 IISISDLSREQLECLLQTALKLKAHPR----GDLLEGKLIGSCFFEPSTRTRLSFETAVQ 65
Query: 70 HLGGHAL-YLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVIN 128
LGG + + + + ++GET+ADTAR++S Y DAI+ R A+++ VPVIN
Sbjct: 66 RLGGKVIGFSDGANTSAKKGETLADTARIISGYTDAIIQRHPKDGAARVAAEFSRVPVIN 125
Query: 129 -GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGADVVVA 185
G HP Q L D +TI+E +G + +K+ GD HSL A + +
Sbjct: 126 AGDGTNQHPSQTLLDLVTIYETQGRLDKLKIAMAGDLKYGRTVHSLCQALKRWNCEFAFV 185
Query: 186 TPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERR 245
+P P + + + E+G + +L +A + AD++Y + + + +E
Sbjct: 186 SP----PSLAMPDYITEELDEAGCRYRILGSLEEAAEWADILY--MTRVQRERFDEQEFA 239
Query: 246 KIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAV 305
KI F + ++ AKP+ +H LP R +E+ DV +P++ +++A N ++A+ A+
Sbjct: 240 KIQGKFNLEASMLARAKPNLRVLHPLP--RVDEIHPDVDATPHAYYFEQATNGVYARMAI 297
Query: 306 LALLL 310
L+L+L
Sbjct: 298 LSLVL 302
>sp|Q08016|OTC1_SALTY ORNITHINE CARBAMOYLTRANSFERASE CHAIN I (OTCASE-1)
>gi|421212|pir||S34359 ornithine carbamoyltransferase
(EC 2.1.3.3) chain I - Salmonella typhimurium (fragment)
>gi|312706|emb|CAA51780.1| (X73368) arnithine
carbamoyltransferase [Salmonella typhimurium]
Length = 218
Score = 138 bits (345), Expect = 7e-32
Identities = 83/212 (39%), Positives = 116/212 (54%), Gaps = 3/212 (1%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
+ L L D+T E+ +L+ A LK +K GK + L GK +A+IF+K STRTR SFEVA
Sbjct: 7 KPFLKLLDFTASELTALLQLAAKLKADKKNGKEEQKLVGKNIALIFEKDSTRTRCSFEVA 66
Query: 68 MAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVI 127
G YL + Q+ E+I DTARVL R D I R Y + VE LA+Y+ VPV
Sbjct: 67 AYDQGARVTYLGSSGSQIGHKESIKDTARVLGRMFDGIQYRGYGQEIVETLAEYSGVPVW 126
Query: 128 NGLSDFSHPCQALADYMTIWE--KKGTIKGVKVVYVGDG-NNVAHSLMIAGTKLGADVVV 184
NGL+D HP Q LAD +T+ E + +VY GD NN+ +S++ A G D+ +
Sbjct: 127 NGLTDEYHPTQLLADLLTMQEHLPGKAFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRL 186
Query: 185 ATPEGYEPDEKVIKWAEQNAAESGGSFELLHD 216
P+ P ++ A ++GG+ L D
Sbjct: 187 VAPKACWPQAALVAECSAMAKKNGGAITLTED 218
>sp|O58451|PYRB_PYRHO ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE TRANSCARBAMYLASE)
(ATCASE) >gi|7433581|pir||A71119 probable aspartate
carbamoyltransferase catalytic chain - Pyrococcus
horikoshii >gi|3257128|dbj|BAA29811.1| (AP000003) 308aa
long hypothetical aspartate carbamoyltransferase
catalytic chain [Pyrococcus horikoshii]
Length = 308
Score = 130 bits (323), Expect = 3e-29
Identities = 91/310 (29%), Positives = 161/310 (51%), Gaps = 11/310 (3%)
Query: 6 KGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFE 65
KGRD++ ++D++ E+I +L TA+ L+ K +GK LA +F +PSTRTR+SFE
Sbjct: 4 KGRDVISIRDFSKEDIEVVLSTAERLEKEMKEKGQLEYAKGKILATLFFEPSTRTRLSFE 63
Query: 66 VAMAHLGGHAL-YLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASV 124
AM LGG + + A +++GE++ DT + + +Y D I+ R A+ A +
Sbjct: 64 SAMHRLGGSVIGFAEASTSSVKKGESLRDTIKTVEQYSDVIVIRHPKEGAARLAAEVADI 123
Query: 125 PVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGAD 181
PVIN G HP Q L D TI ++ GTI G+K+ +GD HSL A +
Sbjct: 124 PVINAGDGSNQHPTQTLLDLYTIKKEFGTIDGLKIGLLGDLKYGRTVHSLAEALAFYDVE 183
Query: 182 VVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA 241
+ + +PE + +++ + + + +L + + + DV+Y + +
Sbjct: 184 LYLISPELLRMPKHIVEELRERGMKIVETTKL----EEVIGELDVLYV-TRIQKERFPDE 238
Query: 242 EERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHA 301
+E K+ +QVN ++++ K MH LP R +E+ +V + +++ + + N +
Sbjct: 239 QEYLKVKGSYQVNLKILENVKDSLRIMHPLP--RVDEIHPEVDKTKHAIYFKQVFNGVPV 296
Query: 302 QKAVLALLLG 311
+ A+LAL+LG
Sbjct: 297 RMALLALVLG 306
>sp|P77918|PYRB_PYRAB ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE TRANSCARBAMYLASE)
(ATCASE) >gi|7433599|pir||C75042 aspartate
carbamoyltransferase, catalytic chain (pyrb) PAB1498 -
Pyrococcus abyssi (strain Orsay)
>gi|1572497|gb|AAB62984.1| (U61765) aspartate
transcarbamylase catalytic chain [Pyrococcus abyssi]
>gi|5458745|emb|CAB50232.1| (AJ248287) aspartate
carbamoyltransferase, catalytic subunit (pyrB)
[Pyrococcus abyssi]
Length = 308
Score = 129 bits (322), Expect = 3e-29
Identities = 95/310 (30%), Positives = 158/310 (50%), Gaps = 11/310 (3%)
Query: 6 KGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFE 65
KGRD++ ++D++ E+I T+L TA+ L+ K +GK LA +F +PSTRTR+SFE
Sbjct: 4 KGRDVISIRDFSKEDIETVLATAERLERELKEKGQLEYAKGKILATLFFEPSTRTRLSFE 63
Query: 66 VAMAHLGGHAL-YLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASV 124
AM LGG + + A +++GE++ DT + + +Y D I+ R A+ A V
Sbjct: 64 SAMHRLGGAVIGFAEASTSSVKKGESLRDTIKTVEQYCDVIVIRHPKEGAARLAAEVAEV 123
Query: 125 PVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGAD 181
PVIN G HP Q L D TI ++ G I G+K+ +GD HSL A T +
Sbjct: 124 PVINAGDGSNQHPTQTLLDLYTIKKEFGRIDGLKIGLLGDLKYGRTVHSLAEALTFYDVE 183
Query: 182 VVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA 241
+ + +PE ++ + E G + DV+Y + +
Sbjct: 184 LYLISPELLRMPRHIV----EELREKGMKVVETTTLEDVIGKLDVLYV-TRIQKERFPDE 238
Query: 242 EERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHA 301
+E K+ +QVN +++ AK + MH LP R +E+ +V ++ +++ + + N +
Sbjct: 239 QEYLKVKGSYQVNLKVLEKAKDELRIMHPLP--RVDEIHPEVDNTKHAIYFRQVFNGVPV 296
Query: 302 QKAVLALLLG 311
+ A+LAL+LG
Sbjct: 297 RMALLALVLG 306
>sp|Q91437|PYR1_SQUAC CAD PROTEIN [INCLUDES: GLUTAMINE-DEPENDENT CARBAMOYL-PHOSPHATE
SYNTHASE ; ASPARTATE CARBAMOYLTRANSFERASE ;
DIHYDROOROTASE ] >gi|2118285|pir||A57541 pyrimidine
synthesis multifunctional protein CAD - spiny dogfish
>gi|951096|gb|AAA74569.1| (U18868) multifunctional
protein CAD [Squalus acanthias]
Length = 2242
Score = 128 bits (318), Expect = 1e-28
Identities = 90/308 (29%), Positives = 152/308 (49%), Gaps = 10/308 (3%)
Query: 7 GRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEV 66
G+ +L ++ +T +++ + A L++ + + +L+GK +A +F + STRT SF
Sbjct: 1940 GQHILSVKRFTKDQLSHLFNVAHNLRLTVQKDRSLDILKGKVMASMFYEVSTRTSSSFRA 1999
Query: 67 AMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPV 126
AM LGG ++ + +++GE++ D+ + +S YVD ++ R + VE AK++ P+
Sbjct: 2000 AMHRLGGSVIHFSEATSSVQKGESLLDSVQTMSCYVDVVVLRHPEPGAVELAAKHSRKPI 2059
Query: 127 IN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGADVV 183
IN G HP QAL D TI E+ GT+ G+ + VGD HSL T ++
Sbjct: 2060 INAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLAYLLTLYRVNLR 2119
Query: 184 VATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEE 243
TP +I++ A G E +A+ D DV+Y + A EE
Sbjct: 2120 YVTPRNLRMPPNIIRF----LASRGIKQEEFDSLEEALPDTDVLYM-TRIQKERFASEEE 2174
Query: 244 RRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQK 303
F F + ++ K + MH LP R EV+ +V P + + +AEN ++ +
Sbjct: 2175 YEACFGQFILTPHIMTKGKKKMVVMHPLP--RVNEVSVEVDSDPRAAYFRQAENGMYVRM 2232
Query: 304 AVLALLLG 311
A+LA +LG
Sbjct: 2233 ALLATVLG 2240
>pir||A36240 pyrimidine synthesis protein CAD - human (fragment)
>gi|179770|gb|AAA51907.1| (M38561) CAD [Homo sapiens]
Length = 474
Score = 127 bits (317), Expect = 1e-28
Identities = 92/311 (29%), Positives = 150/311 (47%), Gaps = 10/311 (3%)
Query: 4 SLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVS 63
SL G+ +L +Q +T +++ + A L++ + + +L+GK +A +F + STRT S
Sbjct: 169 SLVGQHILSVQQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSS 228
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
F AMA LGG L + +++GE++AD+ + +S Y D ++ R VE AK+
Sbjct: 229 FAAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCR 288
Query: 124 VPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGA 180
PVIN G HP QAL D TI E+ GT+ G+ + VGD HSL T+
Sbjct: 289 RPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRV 348
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
+ P P ++ A G E +A+ D DV+Y +
Sbjct: 349 SLRYVAP----PSLRMPPTVRAFVASRGTKQEEFESIEEALPDTDVLYM-TRIQKERFGS 403
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
+E F F + ++ AK + MH +P R E++ +V P + + +AEN ++
Sbjct: 404 TQEYEACFGQFILTPHIMTRAKKKMVVMHPMP--RVNEISVEVDSDPRAAYFRQAENGMY 461
Query: 301 AQKAVLALLLG 311
+ A+LA +LG
Sbjct: 462 IRMALLATVLG 472
>gi|4757896 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and
dihydroorotase; CAD trifunctional protein of pyrimidine
biosynthesis [Homo sapiens]
>gi|1709955|sp|P27708|PYR1_HUMAN CAD PROTEIN [INCLUDES:
GLUTAMINE-DEPENDENT CARBAMOYL-PHOSPHATE SYNTHASE ;
ASPARTATE CARBAMOYLTRANSFERASE ; DIHYDROOROTASE ]
>gi|1228049|dbj|BAA11423.1| (D78586) multifunctional
protein CAD [Homo sapiens]
Length = 2225
Score = 127 bits (317), Expect = 1e-28
Identities = 92/311 (29%), Positives = 150/311 (47%), Gaps = 10/311 (3%)
Query: 4 SLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVS 63
SL G+ +L +Q +T +++ + A L++ + + +L+GK +A +F + STRT S
Sbjct: 1920 SLVGQHILSVQQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSS 1979
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
F AMA LGG L + +++GE++AD+ + +S Y D ++ R VE AK+
Sbjct: 1980 FAAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCR 2039
Query: 124 VPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGA 180
PVIN G HP QAL D TI E+ GT+ G+ + VGD HSL T+
Sbjct: 2040 RPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRV 2099
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
+ P P ++ A G E +A+ D DV+Y +
Sbjct: 2100 SLRYVAP----PSLRMPPTVRAFVASRGTKQEEFESIEEALPDTDVLYM-TRIQKERFGS 2154
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
+E F F + ++ AK + MH +P R E++ +V P + + +AEN ++
Sbjct: 2155 TQEYEACFGQFILTPHIMTRAKKKMVVMHPMP--RVNEISVEVDSDPRAAYFRQAENGMY 2212
Query: 301 AQKAVLALLLG 311
+ A+LA +LG
Sbjct: 2213 IRMALLATVLG 2223
>sp|P08955|PYR1_MESAU CAD PROTEIN [INCLUDES: GLUTAMINE-DEPENDENT CARBAMOYL-PHOSPHATE
SYNTHASE ; ASPARTATE CARBAMOYLTRANSFERASE ;
DIHYDROOROTASE ] >gi|538556|pir||A23443 pyrimidine
synthesis multifunctional protein CAD - golden hamster
Length = 2225
Score = 125 bits (311), Expect = 7e-28
Identities = 92/311 (29%), Positives = 149/311 (47%), Gaps = 10/311 (3%)
Query: 4 SLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVS 63
SL G+ +L ++ +T +++ + A L++ + + +L+GK +A +F + STRT S
Sbjct: 1920 SLVGQHILSVKQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSS 1979
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
F AMA LGG L + +++GE++AD+ + +S Y D ++ R VE AK+
Sbjct: 1980 FAAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCR 2039
Query: 124 VPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGA 180
PVIN G HP QAL D TI E+ GT+ G+ + VGD HSL T+
Sbjct: 2040 RPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRV 2099
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
+ P V W A G E +A+ D DV+Y +
Sbjct: 2100 SLRYVAPPSLRMPPSV--W--DFVASRGTKQEEFESIEEALPDTDVLYM-TRIQKERFGS 2154
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
+E F F + ++ AK + MH +P R E++ +V P + + +AEN ++
Sbjct: 2155 TQEYEACFGQFILTPHIMTRAKKKMVVMHPMP--RVNEISVEVDSDPRAAYFRQAENGMY 2212
Query: 301 AQKAVLALLLG 311
+ A+LA +LG
Sbjct: 2213 IRMALLATVLG 2223
>gb|AAA37064.1| (M23652) CAD protein [Mesocricetus auratus]
Length = 452
Score = 125 bits (311), Expect = 7e-28
Identities = 92/311 (29%), Positives = 149/311 (47%), Gaps = 10/311 (3%)
Query: 4 SLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVS 63
SL G+ +L ++ +T +++ + A L++ + + +L+GK +A +F + STRT S
Sbjct: 147 SLVGQHILSVKQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSS 206
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
F AMA LGG L + +++GE++AD+ + +S Y D ++ R VE AK+
Sbjct: 207 FAAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCR 266
Query: 124 VPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGA 180
PVIN G HP QAL D TI E+ GT+ G+ + VGD HSL T+
Sbjct: 267 RPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRV 326
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
+ P V W A G E +A+ D DV+Y +
Sbjct: 327 SLRYVAPPSLRMPPSV--W--DFVASRGTKQEEFESIEEALPDTDVLYM-TRIQKERFGS 381
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
+E F F + ++ AK + MH +P R E++ +V P + + +AEN ++
Sbjct: 382 TQEYEACFGQFILTPHIMTRAKKKMVVMHPMP--RVNEISVEVDSDPRAAYFRQAENGMY 439
Query: 301 AQKAVLALLLG 311
+ A+LA +LG
Sbjct: 440 IRMALLATVLG 450
>sp|P96174|PYRB_VIBS2 ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN (ASPARTATE
TRANSCARBAMYLASE) (ATCASE) >gi|11257123|pir||T48882
aspartate carbamoyltransferase (EC 2.1.3.2) catalytic
chain [validated] - Vibrio sp
>gi|1708787|emb|CAA70923.1| (Y09786) aspartate
carbamoyltransferase (ATCase) catalytic chain (c)
[Vibrio sp.]
Length = 310
Score = 123 bits (306), Expect = 3e-27
Identities = 106/325 (32%), Positives = 166/325 (50%), Gaps = 38/325 (11%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
+ ++ + D + E+ I++TA LK K +P LL+ K +A F + STRTR+SFE A
Sbjct: 8 KHIVSINDISRNELELIVKTAAKLK---KQPQPE-LLKNKVIASCFFEASTRTRLSFETA 63
Query: 68 MAHLGGHAL-YLNAQDLQL-RRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVP 125
+ LGG + + NA + L ++GET+AD+ V+S YVDA + R +++++VP
Sbjct: 64 IQRLGGTVIGFDNASNTSLAKKGETLADSISVISSYVDAFVMRHPQEGAARLASEFSNVP 123
Query: 126 VINGLSDFS--HPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLG-- 179
VING D S HP Q L D +I+E +G + + + VGD HSL A K
Sbjct: 124 VING-GDGSNQHPTQTLLDLFSIYETQGCLDNLNIALVGDLKYGRTVHSLAQALAKFSGC 182
Query: 180 -----ADVVVATPEGY--EPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIY-TDV 231
A +A PE E DE + +A N+ E + V + DV+Y T V
Sbjct: 183 KFYFIAPDALAMPEYICDELDEHNVSYACYNSIE------------EVVPEIDVLYMTRV 230
Query: 232 WASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVV 291
E E + + F ++ +KHAK + +H LP R +E+ DV +P +
Sbjct: 231 QKERFDETEYQHMK---AGFILSASSLKHAKDNLKVLHPLP--RVDEIAVDVDKTPYAYY 285
Query: 292 WDEAENRLHAQKAVLALLLGGVKTG 316
+ +AEN ++A++A+LAL+L G
Sbjct: 286 FQQAENGVYAREALLALVLNATIEG 310
>sp|Q58976|PYRB_METJA ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE TRANSCARBAMYLASE)
(ATCASE) >gi|2127771|pir||D64497 aspartate
carbamoyltransferase (EC 2.1.3.2) catalytic chain -
Methanococcus jannaschii >gi|1500476|gb|AAB99601.1|
(U67598) aspartate carbamoyltransferase catalytic chain
(pyrB) [Methanococcus jannaschii]
Length = 306
Score = 122 bits (304), Expect = 4e-27
Identities = 93/310 (30%), Positives = 157/310 (50%), Gaps = 18/310 (5%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
+ L+ ++D EEI IL+ A+ ++ +P +LLEGK LA +F +PSTRTR+SFE A
Sbjct: 2 KHLISMKDIGKEEILEILDEARKMEELLNTKRPLKLLEGKILATVFYEPSTRTRLSFETA 61
Query: 68 MAHLGGHALYL-NAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPV 126
M LGG + + + + + +GE++ DT RV+S Y D I+ R ++Y+ VP+
Sbjct: 62 MKRLGGEVITMTDLKSSSVAKGESLIDTIRVISGYADIIVLRHPSEGAARLASEYSQVPI 121
Query: 127 IN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKL-GADV 182
IN G HP Q L D TI + G I G+K+ +VGD HSL+ A + ++
Sbjct: 122 INAGDGSNQHPTQTLLDLYTIMREIGRIDGIKIAFVGDLKYGRTVHSLVYALSLFENVEM 181
Query: 183 VVATPEGYEPDEKVIK--WAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
+P+ + +I+ A+ S + L D D DV+Y + +
Sbjct: 182 YFVSPKELRLPKDIIEDLKAKNIKFYEKESLDDLDD------DIDVLYV-TRIQKERFPD 234
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
E K+ +++ ++ V+ K ++ MH LP R +E+ DV D P + + ++ +
Sbjct: 235 PNEYEKVKGSYKIKREYVEGKK--FIIMHPLP--RVDEIDYDVDDLPQAKYFKQSFYGIP 290
Query: 301 AQKAVLALLL 310
+ A+L L+
Sbjct: 291 VRMAILKKLI 300
>emb|CAC11715.1| (AL445064) probable aspartate carbamoyltransferase, catalytic chain
[Thermoplasma acidophilum]
Length = 305
Score = 122 bits (304), Expect = 4e-27
Identities = 92/314 (29%), Positives = 160/314 (50%), Gaps = 18/314 (5%)
Query: 5 LKGRDLLCLQDYTPEEIWTILETA-KMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVS 63
LK R ++ ++D +++ + + + MLK +K G LL + +A +F +PSTRTR+S
Sbjct: 2 LKNRSVVSIEDVDIDDLNDLFDLSDSMLKTIEKGGSTD-LLRNRIMATLFYEPSTRTRLS 60
Query: 64 FEVAMAHLGGHALYL-NAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYA 122
FE AM LGG + + + + + +GET+ADT R+ S Y D I+ R +K+A
Sbjct: 61 FESAMHRLGGSVITVSDVKTSSVAKGETLADTIRMASSYSDIIVIRHPLEGAARLASKFA 120
Query: 123 SVPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLG 179
+ PVIN G HP Q + D TI + G+I G + VGD HSL+IA ++
Sbjct: 121 NKPVINAGDGSGQHPTQTILDLYTIKRETGSIDGKTITMVGDLRYGRTIHSLIIALSRFD 180
Query: 180 ADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLH--DPVKAVKDADVIYTDVWASMGQ 237
+ + +P+ ++K E + G ++ D K ++D DV+Y +
Sbjct: 181 VRINLVSPQ-------ILKLPEYVLTKIGDRSRIMEYDDLSKVIEDTDVLYV-TRIQKER 232
Query: 238 EAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAEN 297
++ E + + + V++DLV K D + MH LP R +E+ +V + P + + +A
Sbjct: 233 FSDQNEYQSVIGSYSVDRDLVSRMKKDAIIMHPLP--RIDEIKPEVDELPQARYFKQAYY 290
Query: 298 RLHAQKAVLALLLG 311
+ + A++ +LG
Sbjct: 291 GVPVRMALIYRILG 304
>pir||D75435 aspartate carbamoyltransferase - Deinococcus radiodurans (strain
R1) >gi|6458844|gb|AAF10682.1|AE001961_1 (AE001961)
aspartate carbamoyltransferase [Deinococcus radiodurans]
Length = 314
Score = 122 bits (303), Expect = 6e-27
Identities = 101/314 (32%), Positives = 156/314 (49%), Gaps = 22/314 (7%)
Query: 8 RDLLCLQDYTPEEIWTILETAK-MLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEV 66
R LL QD+TPE + +L+ A ML++ + K L+G T+ F + STRTR SFE+
Sbjct: 12 RHLLDFQDWTPERLEAVLDNADTMLQVLDRPVKKVPALQGLTVCTAFFENSTRTRTSFEL 71
Query: 67 AMAHLGGHALYLNAQDLQLRRGETIADTARVLSRY-VDAIMARVYDHKDVEDLAKYASVP 125
A + + A + + +GE++ DT VL+ Y VDA + R + +AKY+ P
Sbjct: 72 AARRMSADVVSFAAGNSSVSKGESLRDTIEVLTAYKVDAYVVRHHAAGAAHLVAKYSGKP 131
Query: 126 VIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGADV 182
VIN G +HP QAL D TI ++ G+++G KV +GD + VA S KLGA+V
Sbjct: 132 VINAGDGRRAHPTQALLDAYTIRQEYGSLEGKKVAIIGDIRHSRVARSNAELLPKLGAEV 191
Query: 183 VVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYT----DVWASMGQE 238
V+ P P + A + G L DP +AV+ A + + G
Sbjct: 192 VLCGPATLLPPDL--------AGQPG--VRLTTDPREAVRGAHAVMALRLQQERMNGGYL 241
Query: 239 AEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENR 298
A +E +QVN+ L++ A+ + +H P +R E++ + D P S + + EN
Sbjct: 242 ASLQEYAD---TYQVNETLMREAESGAIVLHPGPMNRDLEISTEAADGPRSRIIRQVENG 298
Query: 299 LHAQKAVLALLLGG 312
+ +VL LL G
Sbjct: 299 QAVRMSVLYHLLVG 312
>sp|P05654|PYRB_BACSU ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE TRANSCARBAMYLASE)
(ATCASE) >gi|279485|pir||OWBSAC aspartate
carbamoyltransferase (EC 2.1.3.2) catalytic chain
[validated] - Bacillus subtilis
>gi|143384|gb|AAA22685.1| (M13128) aspartate
transcarbamoylase (EC 2.1.3.2) [Bacillus subtilis]
>gi|143387|gb|AAA21267.1| (M59757) aspartate
transcarbamylase [Bacillus subtilis]
>gi|2633922|emb|CAB13423.1| (Z99112) aspartate
carbamoyltransferase [Bacillus subtilis]
Length = 304
Score = 121 bits (300), Expect = 1e-26
Identities = 92/307 (29%), Positives = 153/307 (48%), Gaps = 23/307 (7%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
+ L + + + EEI +L+TA+ LK GK L GK A +F +PSTRTR SFEVA
Sbjct: 2 KHLTTMSELSTEEIKDLLQTAQELKS----GKTDNQLTGKFAANLFFEPSTRTRFSFEVA 57
Query: 68 MAHLGGHALYLNAQDLQLRRGETIADTARVL-SRYVDAIMARVYDHKDVEDLAKYASVPV 126
LG + L L+ +++GET+ DT R L S VD + R + + E+L ++P+
Sbjct: 58 EKKLGMNVLNLDGTSTSVQKGETLYDTIRTLESIGVDVCVIRHSEDEYYEELVSQVNIPI 117
Query: 127 IN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGADVV 183
+N G HP Q+L D MTI+E+ T KG+ V GD + VA S T+LGA V+
Sbjct: 118 LNAGDGCGQHPTQSLLDLMTIYEEFNTFKGLTVSIHGDIKHSRVARSNAEVLTRLGARVL 177
Query: 184 VATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEE 243
+ P ++ +E G++ + + AV+ +DV+ + + A
Sbjct: 178 FSGPSEWQDEENTF-----------GTYVSMDE---AVESSDVVML-LRIQNERHQSAVS 222
Query: 244 RRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQK 303
+ + + + + K + MH P +RG E+ D +++S S ++ + +N + +
Sbjct: 223 QEGYLNKYGLTVERAERMKRHAIIMHPAPVNRGVEIDDSLVESEKSRIFKQMKNGVFIRM 282
Query: 304 AVLALLL 310
AV+ L
Sbjct: 283 AVIQCAL 289
>pdb|2AT2|A Chain A, Aspartate Transcarbamoylase (E.C.2.1.3.2) (Aspartate
Carbamoyltransferase) >gi|494730|pdb|2AT2|B Chain B,
Aspartate Transcarbamoylase (E.C.2.1.3.2) (Aspartate
Carbamoyltransferase) >gi|494731|pdb|2AT2|C Chain C,
Aspartate Transcarbamoylase (E.C.2.1.3.2) (Aspartate
Carbamoyltransferase)
Length = 300
Score = 121 bits (300), Expect = 1e-26
Identities = 92/307 (29%), Positives = 153/307 (48%), Gaps = 23/307 (7%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
+ L + + + EEI +L+TA+ LK GK L GK A +F +PSTRTR SFEVA
Sbjct: 2 KHLTTMSELSTEEIKDLLQTAQELKS----GKTDNQLTGKFAANLFFEPSTRTRFSFEVA 57
Query: 68 MAHLGGHALYLNAQDLQLRRGETIADTARVL-SRYVDAIMARVYDHKDVEDLAKYASVPV 126
LG + L L+ +++GET+ DT R L S VD + R + + E+L ++P+
Sbjct: 58 EKKLGMNVLNLDGTSTSVQKGETLYDTIRTLESIGVDVCVIRHSEDEYYEELVSQVNIPI 117
Query: 127 IN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGADVV 183
+N G HP Q+L D MTI+E+ T KG+ V GD + VA S T+LGA V+
Sbjct: 118 LNAGDGCGQHPTQSLLDLMTIYEEFNTFKGLTVSIHGDIKHSRVARSNAEVLTRLGARVL 177
Query: 184 VATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEE 243
+ P ++ +E G++ + + AV+ +DV+ + + A
Sbjct: 178 FSGPSEWQDEENTF-----------GTYVSMDE---AVESSDVVML-LRIQNERHQSAVS 222
Query: 244 RRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQK 303
+ + + + + K + MH P +RG E+ D +++S S ++ + +N + +
Sbjct: 223 QEGYLNKYGLTVERAERMKRHAIIMHPAPVNRGVEIDDSLVESEKSRIFKQMKNGVFIRM 282
Query: 304 AVLALLL 310
AV+ L
Sbjct: 283 AVIQCAL 289
>emb|CAA32782.1| (X14634) PYR1-3B multifunctional enzyme (1014 AA) [Dictyostelium
discoideum]
Length = 1014
Score = 120 bits (298), Expect = 2e-26
Identities = 85/311 (27%), Positives = 144/311 (45%), Gaps = 10/311 (3%)
Query: 4 SLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVS 63
SL G+ + ++ + +++ + A ++I K LL+GK LA +F +PSTRT+ S
Sbjct: 708 SLAGKHIFSVKQFNRKQLHALFGIAHEMRILVKRSGGSDLLKGKVLATLFYEPSTRTQCS 767
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
F AM LGG + ++ + +GE+IADT + L Y DA+ R VE + A
Sbjct: 768 FTAAMQRLGGSVVTVDNVSSSVAKGESIADTIQTLESYCDAVCMRHPAVGSVESAIQVAK 827
Query: 124 VPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGA 180
P+IN G HP QAL D TI E+ GT+ G+ + VGD HSL+
Sbjct: 828 KPIINAGDGVGEHPTQALLDVFTIREELGTVNGLTITVVGDLKHGRTVHSLVRLLANYQV 887
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
+ +P ++IK + E + + ++++ + +
Sbjct: 888 KINYVSPSSLSMPTEIIKELNEKGIE-----QKEYTNIESILPTTNVLYVTRVQKERFQS 942
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
EE K+ F + + A + + MH LP R E++ +V P + + + EN L+
Sbjct: 943 IEEYEKVKDSFIITPHTLTKASDNMIVMHPLP--RINEISPEVDSDPRAAYFRQMENGLY 1000
Query: 301 AQKAVLALLLG 311
+ ++LAL+ G
Sbjct: 1001 VRMSLLALVFG 1011
>pir||QZDOP3 pyrimidine synthesis protein PYR1-3 - slime mold (Dictyostelium
discoideum) (fragments)
Length = 1481
Score = 120 bits (298), Expect = 2e-26
Identities = 85/311 (27%), Positives = 144/311 (45%), Gaps = 10/311 (3%)
Query: 4 SLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVS 63
SL G+ + ++ + +++ + A ++I K LL+GK LA +F +PSTRT+ S
Sbjct: 1175 SLAGKHIFSVKQFNRKQLHALFGIAHEMRILVKRSGGSDLLKGKVLATLFYEPSTRTQCS 1234
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
F AM LGG + ++ + +GE+IADT + L Y DA+ R VE + A
Sbjct: 1235 FTAAMQRLGGSVVTVDNVSSSVAKGESIADTIQTLESYCDAVCMRHPAVGSVESAIQVAK 1294
Query: 124 VPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGA 180
P+IN G HP QAL D TI E+ GT+ G+ + VGD HSL+
Sbjct: 1295 KPIINAGDGVGEHPTQALLDVFTIREELGTVNGLTITVVGDLKHGRTVHSLVRLLANYQV 1354
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
+ +P ++IK + E + + ++++ + +
Sbjct: 1355 KINYVSPSSLSMPTEIIKELNEKGIE-----QKEYTNIESILPTTNVLYVTRVQKERFQS 1409
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
EE K+ F + + A + + MH LP R E++ +V P + + + EN L+
Sbjct: 1410 IEEYEKVKDSFIITPHTLTKASDNMIVMHPLP--RINEISPEVDSDPRAAYFRQMENGLY 1467
Query: 301 AQKAVLALLLG 311
+ ++LAL+ G
Sbjct: 1468 VRMSLLALVFG 1478
>sp|P20054|PYR1_DICDI PROTEIN PYR1-3 [INCLUDES: GLUTAMINE-DEPENDENT CARBAMOYL-PHOSPHATE
SYNTHASE ; ASPARTATE CARBAMOYLTRANSFERASE ;
DIHYDROOROTASE ]
Length = 2185
Score = 120 bits (298), Expect = 2e-26
Identities = 85/311 (27%), Positives = 144/311 (45%), Gaps = 10/311 (3%)
Query: 4 SLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVS 63
SL G+ + ++ + +++ + A ++I K LL+GK LA +F +PSTRT+ S
Sbjct: 1879 SLAGKHIFSVKQFNRKQLHALFGIAHEMRILVKRSGGSDLLKGKVLATLFYEPSTRTQCS 1938
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
F AM LGG + ++ + +GE+IADT + L Y DA+ R VE + A
Sbjct: 1939 FTAAMQRLGGSVVTVDNVSSSVAKGESIADTIQTLESYCDAVCMRHPAVGSVESAIQVAK 1998
Query: 124 VPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGA 180
P+IN G HP QAL D TI E+ GT+ G+ + VGD HSL+
Sbjct: 1999 KPIINAGDGVGEHPTQALLDVFTIREELGTVNGLTITVVGDLKHGRTVHSLVRLLANYQV 2058
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
+ +P ++IK + E + + ++++ + +
Sbjct: 2059 KINYVSPSSLSMPTEIIKELNEKGIE-----QKEYTNIESILPTTNVLYVTRVQKERFQS 2113
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
EE K+ F + + A + + MH LP R E++ +V P + + + EN L+
Sbjct: 2114 IEEYEKVKDSFIITPHTLTKASDNMIVMHPLP--RINEISPEVDSDPRAAYFRQMENGLY 2171
Query: 301 AQKAVLALLLG 311
+ ++LAL+ G
Sbjct: 2172 VRMSLLALVFG 2182
>gb|AAF48639.2| (AE003503) CG18572 gene product [Drosophila melanogaster]
Length = 2188
Score = 120 bits (298), Expect = 2e-26
Identities = 86/316 (27%), Positives = 152/316 (47%), Gaps = 11/316 (3%)
Query: 4 SLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKP-HRLLEGKTLAMIFQKPSTRTRV 62
SL G+ +L + + + + I A++LK+ +P LL GK +A +F + STRT+
Sbjct: 1878 SLMGKHILAVDMFNKDHLNDIFNLAQLLKLRGTKDRPVDELLPGKIMASVFYEVSTRTQC 1937
Query: 63 SFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYA 122
SF AM LGG + ++ +++GE++ D+ +V+S Y D ++ R V A ++
Sbjct: 1938 SFAAAMLRLGGRVISMDNITSSVKKGESLEDSIKVVSSYADVVVLRHPSPGAVARAATFS 1997
Query: 123 SVPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNN--VAHSLMIAGTKLG 179
P+IN G HP QAL D TI E+ GT+ G+ + VGD N HSL T
Sbjct: 1998 RKPLINAGDGVGEHPTQALLDIFTIREEFGTVNGLTITMVGDLKNGRTVHSLARLLTLYN 2057
Query: 180 ADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEA 239
++ P + ++V+++ Q + D + D DV+Y +
Sbjct: 2058 VNLQYVAPNSLQMPDEVVQFVHQRGVKQ----LFARDLKNVLPDTDVLYM-TRIQRERFD 2112
Query: 240 EAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRL 299
E+ K + + + AK + +H LP R E++ ++ P + + +AE +
Sbjct: 2113 NVEDYEKCCGHLVLTPEHMMRAKKRSIVLHPLP--RLNEISREIDSDPRAAYFRQAEYGM 2170
Query: 300 HAQKAVLALLLGGVKT 315
+ + A+LA+++GG T
Sbjct: 2171 YIRMALLAMVVGGRNT 2186
>sp|P49077|PYRB_ARATH ASPARTATE CARBAMOYLTRANSFERASE PRECURSOR (ASPARTATE
TRANSCARBAMYLASE) (ATCASE) >gi|1076293|pir||S46441
aspartate carbamoyltransferase (EC 2.1.3.2) -
Arabidopsis thaliana >gi|443820|emb|CAA50687.1| (X71843)
aspartate carbamoyltransferase [Arabidopsis thaliana]
Length = 390
Score = 119 bits (295), Expect = 5e-26
Identities = 95/314 (30%), Positives = 150/314 (47%), Gaps = 20/314 (6%)
Query: 9 DLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAM 68
D++ + + E + I + A+ ++ +K +L+G +A +F +PSTRTR+SFE AM
Sbjct: 86 DVIEGKQFDREMLSAIFDVAREMEKIEKSSSQSEILKGYLMATLFYEPSTRTRLSFESAM 145
Query: 69 AHLGGHALYL-NAQDL-QLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPV 126
LGG L NA++ +GET+ DT R + Y D I+ R ++ A A++PV
Sbjct: 146 KRLGGEVLTTENAREFSSAAKGETLEDTIRTVEGYSDIIVMRHFESGAARKAAATANIPV 205
Query: 127 IN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD---GNNVAHSLMIAGTKLGADV 182
IN G HP QAL D TI + G + G+ V VGD G V + +
Sbjct: 206 INAGDGPGEHPTQALLDVYTIQSEIGKLDGISVALVGDLANGRTVRSLAYLLAKFKDVKI 265
Query: 183 VVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAE 242
+PE + + + + SG +E D ++ DV+Y + Q
Sbjct: 266 YFVSPEIVKMKDDI----KDYLTSSGVEWEESSDLMEVASKCDVVY----QTRIQRERFG 317
Query: 243 ERRKIFR----PFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENR 298
ER ++ F V+KDL+ + + MH LP R +E+T DV P + + +A+N
Sbjct: 318 ERLDLYEAARGKFIVDKDLLGVMQKKAIIMHPLP--RLDEITADVDADPRAAYFRQAKNG 375
Query: 299 LHAQKAVLALLLGG 312
L + A+L LLL G
Sbjct: 376 LFIRMALLKLLLVG 389
>dbj|BAB02813.1| (AB024036) aspartate carbamoyltransferase [Arabidopsis thaliana]
Length = 390
Score = 118 bits (292), Expect = 1e-25
Identities = 94/314 (29%), Positives = 150/314 (46%), Gaps = 20/314 (6%)
Query: 9 DLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAM 68
D++ + + E + I + A+ ++ +K +L+G +A +F +PSTRTR+SFE AM
Sbjct: 86 DVIEGKQFDREMLSAIFDVAREMEKIEKSSSQSEILKGYLMATLFYEPSTRTRLSFESAM 145
Query: 69 AHLGGHALYL-NAQDL-QLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPV 126
LGG L NA++ +GET+ DT R + Y D I+ R ++ A A++PV
Sbjct: 146 KRLGGEVLTTENAREFSSAAKGETLEDTIRTVEGYSDIIVMRHFESGAARKAAATANIPV 205
Query: 127 IN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD---GNNVAHSLMIAGTKLGADV 182
IN G HP QAL D TI + G + G+ V VGD G V + +
Sbjct: 206 INAGDGPGEHPTQALLDVYTIQSEIGKLDGISVALVGDLANGRTVRSLAYLLAKFKDVKI 265
Query: 183 VVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAE 242
+PE + + + + SG +E D ++ DV+Y + Q
Sbjct: 266 YFVSPEIVKMKDDI----KDYLTSSGVEWEESSDLMEVASKCDVVY----QTRIQRERFG 317
Query: 243 ERRKIFR----PFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENR 298
ER ++ + V+KDL+ + + MH LP R +E+T DV P + + +A+N
Sbjct: 318 ERLDLYEAARGKYIVDKDLLGVMQKKAIIMHPLP--RLDEITADVDADPRAAYFRQAKNG 375
Query: 299 LHAQKAVLALLLGG 312
L + A+L LLL G
Sbjct: 376 LFIRMALLKLLLVG 389
>dbj|BAB03303.1| (AB037416) aspartate carbamoyl transferase [Oryza sativa]
>gi|9453918|dbj|BAB03304.1| (AB037417) aspartate
carbamoyl transferase [Oryza sativa]
Length = 363
Score = 117 bits (290), Expect = 2e-25
Identities = 101/327 (30%), Positives = 157/327 (47%), Gaps = 25/327 (7%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPH-----RLLEGKTLAMIFQK 55
+ SL+ D++ Q + + + I E A+ ++ ++ R+LEG +A +F +
Sbjct: 46 VAASLRLGDVIEAQQFDRDALTEIFEVAREMEALERGSSSRGAGRSRVLEGYLMATLFYE 105
Query: 56 PSTRTRVSFEVAMAHLGGHALYL-NAQDL-QLRRGETIADTARVLSRYVDAIMARVYDHK 113
PSTRTR+SFE AM LGG L NA++ +GET+ DT R + Y D I+ R ++
Sbjct: 106 PSTRTRLSFEAAMRRLGGEVLTTENAREFSSAAKGETLEDTIRTVEGYSDIIVLRHFESG 165
Query: 114 DVEDLAKYASVPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD---GNNVAH 169
A A +PVIN G HP QAL D +I + GT+ G+K+ VGD G V
Sbjct: 166 AARRAAATADIPVINAGDGPGQHPTQALLDVYSIEREIGTLDGIKLGLVGDLANGRTVRS 225
Query: 170 SLMIAGTKLGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIY- 228
+ + +P+ + + + ++ E S +LL + DVIY
Sbjct: 226 LAYLIAKYQNIKIYFVSPDVVKMKDDIKEYLTSQGVEWEESSDLL----EVASKCDVIYQ 281
Query: 229 TDVWAS-MGQEAEAEE--RRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVID 285
T + G+ + E R K +V L KHA + MH LP R +E+T DV
Sbjct: 282 TRIQKERFGERIDLYEAARGKYIVDKKVLDVLPKHA----VIMHPLP--RLDEITIDVDS 335
Query: 286 SPNSVVWDEAENRLHAQKAVLALLLGG 312
P + + +A+N L+ + A+L LLL G
Sbjct: 336 DPRAAYFRQAKNGLYIRMALLKLLLVG 362
>pir||H82066 aspartate carbamoyltransferase, catalytic chain VC2510 [imported] -
Vibrio cholerae (group O1 strain N16961)
>gi|9657093|gb|AAF95652.1| (AE004321) aspartate
carbamoyltransferase, catalytic subunit [Vibrio
cholerae]
Length = 330
Score = 116 bits (288), Expect = 3e-25
Identities = 95/322 (29%), Positives = 164/322 (50%), Gaps = 29/322 (9%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPH-RLLEGKTLAMIFQKPSTR 59
M SL + ++ + + + E+ I++TA LK +P+ L++ K +A F +PSTR
Sbjct: 22 MANSLYQKHIISIAELSRAELELIVKTAGQLK-----AQPNPELIKHKVVASCFFEPSTR 76
Query: 60 TRVSFEVAMAHLGGHAL-YLNAQDLQL-RRGETIADTARVLSRYVDAIMARVYDHKDVED 117
TR+SFE A+ +GG + + N + L ++GET+AD+ RV+S YVDA + R E
Sbjct: 77 TRLSFETAIQRIGGSVIGFDNGGNTSLAKKGETLADSVRVISSYVDAFVMR----HPQEG 132
Query: 118 LAKYAS-----VPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAH 169
A+ AS VPVIN G HP Q L D +I+E +G + + V +VGD H
Sbjct: 133 AARLASEFSNGVPVINAGDGSNQHPSQTLLDLYSIFETQGRLDNLDVAFVGDLKYGRTVH 192
Query: 170 SLMIAGTKLGAD-VVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIY 228
SL A K + PE + + + E+G +++ D + + D++Y
Sbjct: 193 SLAQALAKFDNNRFYFVAPEALAMPDYIC----EELDEAGVKYQVFSDMESVIPELDILY 248
Query: 229 TDVWASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPN 288
+ + + E I + + + A+ + +H LP R +E+T DV +P+
Sbjct: 249 --MTRVQKERFDESEYAHIKSAYILTAAHLSDARSNLKVLHPLP--RVDEITTDVDKTPH 304
Query: 289 SVVWDEAENRLHAQKAVLALLL 310
+ +++ EN ++A++A+LAL+L
Sbjct: 305 AYYFEQVENGVYAREALLALVL 326
>sp|Q43087|PYB2_PEA ASPARTATE CARBAMOYLTRANSFERASE 2 PRECURSOR (ASPARTATE
TRANSCARBAMYLASE 2) (ATCASE 2) >gi|7433605|pir||T10181
aspartate carbamoyltransferase (EC 2.1.3.2) - garden pea
>gi|495661|gb|AAA62444.1| (L15798) aspartate
transcarbamoylase [Pisum sativum]
Length = 385
Score = 116 bits (287), Expect = 4e-25
Identities = 91/312 (29%), Positives = 153/312 (48%), Gaps = 16/312 (5%)
Query: 9 DLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAM 68
D++ Q + + + I E A+ ++ ++ ++L+G +A +F +PSTRTR+SFE AM
Sbjct: 81 DVVEAQQFDRDILNAIFEVARDMEKIERNSPESQILKGYLMATLFYEPSTRTRLSFESAM 140
Query: 69 AHLGGHALYL-NAQDL-QLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPV 126
LGG L NA++ +GET+ DT R + Y D I+ R ++ A A +P+
Sbjct: 141 RRLGGEVLTTENAREFSSAAKGETLEDTIRTVEGYSDLIVLRHFESGAARRAATIAGIPI 200
Query: 127 IN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD---GNNVAHSLMIAGTKLGADV 182
+N G HP QAL D TI + G + G+KV VGD G V + +
Sbjct: 201 VNAGDGPGQHPSQALLDVYTIEREIGKLDGIKVGLVGDLANGRTVRSLTYLLAKYKDVKI 260
Query: 183 VVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIY-TDVWAS-MGQEAE 240
+PE + + + + G +E D V+ + DV+Y T + G+ +
Sbjct: 261 YFVSPEVVKMKDDI----KDYLTSKGVDWEESSDLVEVASECDVVYQTRIQKERFGERLD 316
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
E+ + F VN++++ + + MH LP R +E+T DV P + + +A+ L+
Sbjct: 317 LYEKAR--GKFIVNQNILNAMQRHAVIMHPLP--RLDEITVDVDADPRAAYFRQAKYGLY 372
Query: 301 AQKAVLALLLGG 312
+ A+L LLL G
Sbjct: 373 IRMALLKLLLVG 384
>sp|Q43064|PYB3_PEA ASPARTATE CARBAMOYLTRANSFERASE 3 PRECURSOR (ASPARTATE
TRANSCARBAMYLASE 3) (ATCASE 3) >gi|7433584|pir||T06425
aspartate carbamoyltransferase (EC 2.1.3.2) - garden pea
>gi|609344|gb|AAB67857.1| (U05293) aspartate
carbamoyltransferase [Pisum sativum]
Length = 391
Score = 116 bits (287), Expect = 4e-25
Identities = 91/312 (29%), Positives = 153/312 (48%), Gaps = 16/312 (5%)
Query: 9 DLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAM 68
D++ Q + + + I E A+ ++ ++ ++L+G +A +F +PSTRTR+SFE AM
Sbjct: 87 DVIEAQQFDRDILNAIFEIARDMENIERNSPESQILKGYLMATLFYEPSTRTRLSFESAM 146
Query: 69 AHLGGHALYL-NAQDL-QLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPV 126
LGG L NA++ +GET+ DT R + Y D I+ R ++ A A +P+
Sbjct: 147 RRLGGEVLTTENAREFSSAAKGETLEDTIRTVEGYSDLIVLRHFESGAARRAAAIAGIPI 206
Query: 127 IN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD---GNNVAHSLMIAGTKLGADV 182
+N G HP QAL D TI + G + G+KV VGD G V + +
Sbjct: 207 VNAGDGPGQHPSQALLDVYTIEREIGKLDGIKVGLVGDLANGRTVRSLAYLLAKYKDVKI 266
Query: 183 VVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIY-TDVWAS-MGQEAE 240
+PE + + + + G +E D V+ + DV+Y T + G+ +
Sbjct: 267 YFVSPEVVKMKDDI----KDYLTSKGVDWEESSDLVEVASECDVVYQTRIQKERFGERLD 322
Query: 241 AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
E+ + F VN++++ + + MH LP R +E+T DV P + + +A+ L+
Sbjct: 323 LYEKAR--GKFIVNQNILNAMQRHAVIMHPLP--RLDEITVDVDADPRAAYFRQAKYGLY 378
Query: 301 AQKAVLALLLGG 312
+ A+L LLL G
Sbjct: 379 IRMALLKLLLVG 390
>gb|AAD09129.1| (AF112473) PyrABCN [Aspergillus nidulans]
Length = 2275
Score = 114 bits (283), Expect = 1e-24
Identities = 81/281 (28%), Positives = 137/281 (47%), Gaps = 9/281 (3%)
Query: 6 KGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFE 65
K + +L + + ++ + A+ +++ + +L+G+ L +F +PSTRT SF+
Sbjct: 1953 KQKHVLSVNQFNRADLHLLFTVAQEMRLGVQREGVLDILKGRLLCTLFYEPSTRTSASFD 2012
Query: 66 VAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVP 125
VAM LGG + ++ + ++GET+ DT R L Y DA++ R + E AK++ VP
Sbjct: 2013 VAMQRLGGRTIAISTEHSSTKKGETLQDTLRTLGCYGDAVVLRHPEPSSTEVAAKFSPVP 2072
Query: 126 VIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGADV 182
VIN G HP QA D TI E+ GT+ G+ + + GD HSL+ V
Sbjct: 2073 VINGGNGSVEHPTQAFLDLFTIREELGTVGGLTITFTGDLKYGRPVHSLIKLLQFYDVRV 2132
Query: 183 VVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAE 242
+ P+ + + S EL + V +DV+Y+ + A+ E
Sbjct: 2133 QLVAPKDLSLPADIRQQLLATGQLLTESEELTPE---IVARSDVLYS-TRVQKERFADLE 2188
Query: 243 ERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDV 283
+ ++ F ++ L+KHAK + MH LP R EV+++V
Sbjct: 2189 QYERLKNSFIIDNALLKHAKSHMVVMHPLP--RNAEVSEEV 2227
>sp|Q43086|PYB1_PEA ASPARTATE CARBAMOYLTRANSFERASE 1 PRECURSOR (ASPARTATE
TRANSCARBAMYLASE 1) (ATCASE 1) >gi|7433585|pir||T06484
aspartate carbamoyltransferase (EC 2.1.3.2) - garden pea
>gi|495659|gb|AAA62443.1| (M96981) aspartate
carbamoyltransferase [Pisum sativum]
Length = 386
Score = 114 bits (282), Expect = 2e-24
Identities = 90/314 (28%), Positives = 153/314 (48%), Gaps = 20/314 (6%)
Query: 9 DLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAM 68
D++ Q + E + I E A+ ++ + ++L+G +A +F +PSTRTR+SFE AM
Sbjct: 82 DVIEAQQFDRETLSAIFEVARSMENIRGNSSGSQMLKGYLMATLFYEPSTRTRLSFESAM 141
Query: 69 AHLGGHALYL-NAQDL-QLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPV 126
LGG L NA++ +GET+ DT R + Y D I+ R ++ A A++PV
Sbjct: 142 KRLGGDVLTTENAREFSSAAKGETLEDTIRTVEGYSDIIVLRHFESGAARRAAATANIPV 201
Query: 127 IN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD---GNNVAHSLMIAGTKLGADV 182
IN G HP QAL D TI + G + G+KV VGD G V + +
Sbjct: 202 INAGDGPGQHPSQALLDVYTIEREIGKLDGIKVGLVGDLANGRTVRSLAYLLAKYRDVKL 261
Query: 183 VVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAE 242
+P + + + ++ G +E D ++ DV+Y + Q+
Sbjct: 262 YFVSPNVVKMKDDI----KEYLTSKGVEWEESSDLMEVASKCDVVY----QTRIQKERFG 313
Query: 243 ERRKIFR----PFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENR 298
E+ ++ + VN+D++K + + MH LP + +E+ DV + P + + +A+N
Sbjct: 314 EKLNLYEEARGKYIVNQDVLKVMQNHAVVMHPLP--KLDEIEADVDNDPRAAYFRQAKNG 371
Query: 299 LHAQKAVLALLLGG 312
L+ + A+L +LL G
Sbjct: 372 LYIRMALLKVLLLG 385
>gb|AAA68280.1| (M27174) carbamyl phosphate synthetase [Saccharomyces cerevisiae]
Length = 2214
Score = 112 bits (278), Expect = 5e-24
Identities = 87/313 (27%), Positives = 149/313 (46%), Gaps = 17/313 (5%)
Query: 6 KGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFE 65
+GR +L ++ + + + A+ L+ L++G + IF +PSTRT SF
Sbjct: 1909 RGRHILSIKQFKRSDFHVLFAVAQELRARVAREGVLDLMKGHVITTIFFEPSTRTCSSFI 1968
Query: 66 VAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVP 125
AM LGG + +N +++GET+ DT R L+ Y DAI+ R + V AKY+ VP
Sbjct: 1969 AAMERLGGRIVNVNPLVSSVKKGETLQDTIRTLACYSDAIVMRHSEEMSVHIAAKYSPVP 2028
Query: 126 VIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGADV 182
+IN G HP QA D TI E+ GT+ G+ V ++GD HSL +
Sbjct: 2029 IINGGNGSREHPTQAFLDLFTIREEIGTVNGITVTFMGDLKHGRTVHSLCRLLMHYQVRI 2088
Query: 183 VVATPEGYEPDEKVIKWAEQNAAESG-GSFELLHDPVKAVKDADVIYTDVWASMGQEA-- 239
+ +P P+ ++ + + ++G E + + DV+Y + QE
Sbjct: 2089 NLVSP----PELRLPEGLREELRKAGLLGVESIELTPHIISKTDVLY----CTRVQEERF 2140
Query: 240 -EAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENR 298
EE ++ + V+ ++ HAK + MH LP R E+ ++V + + + +
Sbjct: 2141 NSPEEYARLKDTYIVDNKILAHAKENMAIMHPLP--RVNEIKEEVDYDHRAAYFRQMKYG 2198
Query: 299 LHAQKAVLALLLG 311
L + A+LA+++G
Sbjct: 2199 LFVRMALLAMVMG 2211
>emb|CAA60825.1| (X87371) carbamyl phosphate synthetase [Saccharomyces cerevisiae]
Length = 2040
Score = 112 bits (278), Expect = 5e-24
Identities = 87/313 (27%), Positives = 149/313 (46%), Gaps = 17/313 (5%)
Query: 6 KGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFE 65
+GR +L ++ + + + A+ L+ L++G + IF +PSTRT SF
Sbjct: 1735 RGRHILSIKQFKRSDFHVLFAVAQELRAAVAREGVLDLMKGHVITTIFFEPSTRTCSSFI 1794
Query: 66 VAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVP 125
AM LGG + +N +++GET+ DT R L+ Y DAI+ R + V AKY+ VP
Sbjct: 1795 AAMERLGGRIVNVNPLVSSVKKGETLQDTIRTLACYSDAIVMRHSEEMSVHIAAKYSPVP 1854
Query: 126 VIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGADV 182
+IN G HP QA D TI E+ GT+ G+ V ++GD HSL +
Sbjct: 1855 IINGGNGSREHPTQAFLDLFTIREEIGTVNGITVTFMGDLKHGRTVHSLCRLLMHYQVRI 1914
Query: 183 VVATPEGYEPDEKVIKWAEQNAAESG-GSFELLHDPVKAVKDADVIYTDVWASMGQEA-- 239
+ +P P+ ++ + + ++G E + + DV+Y + QE
Sbjct: 1915 NLVSP----PELRLPEGLREELRKAGLLGVESIELTPHIISKTDVLY----CTRVQEERF 1966
Query: 240 -EAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENR 298
EE ++ + V+ ++ HAK + MH LP R E+ ++V + + + +
Sbjct: 1967 NSPEEYARLKDTYIVDNKILAHAKENMAIMHPLP--RVNEIKEEVDYDHRAAYFRQMKYG 2024
Query: 299 LHAQKAVLALLLG 311
L + A+LA+++G
Sbjct: 2025 LFVRMALLAMVMG 2037
>gi|6322331 carbamoyl-phophate synthetase, aspartate transcarbamylase, and
glutamine amidotransferase; Ura2p [Saccharomyces
cerevisiae] >gi|1172782|sp|P07259|PYR1_YEAST URA1 PROTEIN
[INCLUDES: GLUTAMINE-DEPENDENT CARBAMOYL-PHOSPHATE
SYNTHASE ; ASPARTATE CARBAMOYLTRANSFERASE ]
>gi|1070511|pir||QZBYU2 pyrimidine synthesis protein URA2
- yeast (Saccharomyces cerevisiae)
>gi|1008332|emb|CAA89425.1| (Z49405) ORF YJL130c
[Saccharomyces cerevisiae]
Length = 2214
Score = 112 bits (278), Expect = 5e-24
Identities = 87/313 (27%), Positives = 149/313 (46%), Gaps = 17/313 (5%)
Query: 6 KGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFE 65
+GR +L ++ + + + A+ L+ L++G + IF +PSTRT SF
Sbjct: 1909 RGRHILSIKQFKRSDFHVLFAVAQELRAAVAREGVLDLMKGHVITTIFFEPSTRTCSSFI 1968
Query: 66 VAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVP 125
AM LGG + +N +++GET+ DT R L+ Y DAI+ R + V AKY+ VP
Sbjct: 1969 AAMERLGGRIVNVNPLVSSVKKGETLQDTIRTLACYSDAIVMRHSEEMSVHIAAKYSPVP 2028
Query: 126 VIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGADV 182
+IN G HP QA D TI E+ GT+ G+ V ++GD HSL +
Sbjct: 2029 IINGGNGSREHPTQAFLDLFTIREEIGTVNGITVTFMGDLKHGRTVHSLCRLLMHYQVRI 2088
Query: 183 VVATPEGYEPDEKVIKWAEQNAAESG-GSFELLHDPVKAVKDADVIYTDVWASMGQEA-- 239
+ +P P+ ++ + + ++G E + + DV+Y + QE
Sbjct: 2089 NLVSP----PELRLPEGLREELRKAGLLGVESIELTPHIISKTDVLY----CTRVQEERF 2140
Query: 240 -EAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENR 298
EE ++ + V+ ++ HAK + MH LP R E+ ++V + + + +
Sbjct: 2141 NSPEEYARLKDTYIVDNKILAHAKENMAIMHPLP--RVNEIKEEVDYDHRAAYFRQMKYG 2198
Query: 299 LHAQKAVLALLLG 311
L + A+LA+++G
Sbjct: 2199 LFVRMALLAMVMG 2211
>gb|AAG21801.1|AF192346_1 (AF192346) aspartate transcarbamoylase [Burkholderia cepacia]
Length = 431
Score = 112 bits (277), Expect = 6e-24
Identities = 93/316 (29%), Positives = 147/316 (46%), Gaps = 21/316 (6%)
Query: 10 LLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAMA 69
LL + ++ E + + A +++ + K R+LEG L +F + STRTRVSF A
Sbjct: 92 LLSVDQFSRESVEALFRVADVMQPIARRHKISRVLEGAVLGNLFFEASTRTRVSFGAAFC 151
Query: 70 HLGGHALYLNAQDL-QLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVIN 128
LGG + +GE+I DT+RV++ YVDA + R + V + A+ ++PVIN
Sbjct: 152 RLGGSVCDTTGFTFSSMAKGESIYDTSRVMAGYVDAFVIRHPEKGSVAEFARATNLPVIN 211
Query: 129 -GLSDFSHPCQALADYMTI---WEKKGTI-KGVKVVYVGD---GNNVAHSLMIAGTKLGA 180
G HP QAL D TI + + G I G + VGD G V + + G
Sbjct: 212 GGDGPGEHPSQALLDLYTIQREFSRLGKIVDGAHIALVGDLKYGRTVHSLVKLLALYRGL 271
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
+ +P E ++ A +G E D ++ ADV+Y + +E
Sbjct: 272 KFTLVSPPTLEMPAYIV----DQIATNGHVIEQTTDLAAGLRGADVVYA---TRIQKERF 324
Query: 241 AEERRKIFRP-FQVNKDLVKH-AKPDYMFMHCLPAHRGEEVTDDVID---SPNSVVWDEA 295
+E + + P FQ+N+ LV KPD + MH LP D +D P ++ +
Sbjct: 325 TDESFEGYTPDFQINQALVDTVCKPDTLIMHPLPRDSRPGANDLSVDLNRDPRLAIFRQT 384
Query: 296 ENRLHAQKAVLALLLG 311
+N + + A+ A+LLG
Sbjct: 385 DNGIPVRMAIFAVLLG 400
>gb|AAB86625.1| (AF031144) aspartate transcarbamoylase [Plasmodium falciparum]
Length = 339
Score = 109 bits (271), Expect = 3e-23
Identities = 83/323 (25%), Positives = 150/323 (45%), Gaps = 17/323 (5%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
++ +K + ++ + D EE+ IL T+K + K + + LE K +F +PSTRT
Sbjct: 15 IMTKMKNKSVINIDDVDDEELLAILYTSKQFEKILKNNEDSKYLENKVFCSVFLEPSTRT 74
Query: 61 RVSFEVAMAHLGGHALYL-NAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLA 119
R SF+ A+ LG L + + +GET+ D ++LS YVD I+ R K+V+
Sbjct: 75 RCSFDAAILKLGSKVLNITDMNSTSFYKGETVEDAFKILSTYVDGIIYRDPSKKNVDIAV 134
Query: 120 KYASVPVIN-GLSDFSHPCQALADYMTIWE------KKGTIKGVKVVYVGDGNN--VAHS 170
+S P+IN G HP Q+L D+ TI + K + + +VGD N HS
Sbjct: 135 SSSSKPIINAGNGTGEHPTQSLLDFYTIHNYFPFILDRNINKKLNIAFVGDLKNGRTVHS 194
Query: 171 LMIAGTKLGADVVVATPEGYEPDEKVIKWAEQNAAE----SGGSFELLHDPVKAVKDADV 226
L ++ + + + ++ N + S S + + + ++D +
Sbjct: 195 LSKLLSRYNVSFNFVSCKSLNIPKDIVNTITYNLKKNNFYSDDSIKYFDNLEEGLEDVHI 254
Query: 227 IYTDVWASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDS 286
IY + + +E + F ++ +++ + D +H LP R E+ +V +
Sbjct: 255 IYM-TRIQKERFTDVDEYNQYKNAFILSNKTLENTRDDTKILHPLP--RVNEIKVEVDSN 311
Query: 287 PNSVVWDEAENRLHAQKAVLALL 309
P SV + +AEN L+ + A+L L+
Sbjct: 312 PKSVYFTQAENGLYVRMALLYLI 334
>dbj|BAA94298.1| (AB029444) Aspartate carbamoyltransferase [Leishmania mexicana
amazonensis]
Length = 327
Score = 109 bits (269), Expect = 5e-23
Identities = 87/320 (27%), Positives = 149/320 (46%), Gaps = 15/320 (4%)
Query: 4 SLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVS 63
SLKG+ + ++ +I +++ A +K + GK L G+ + +F + S+RT S
Sbjct: 9 SLKGQSVASAAQFSRADIDALIQLALDMKTHIEAGKTIDALRGRVMTPLFFEDSSRTLSS 68
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
F AM LGG + + + +GET+ DT R L Y D ++ R + +E A+
Sbjct: 69 FCAAMMRLGGGVVNFTVETSSVNKGETLQDTVRTLDSYSDVLVLRHVKEEALEQAMSVAT 128
Query: 124 VPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGA 180
P++N G HP QAL D +TI + G + G+ + +GD HSL+ T A
Sbjct: 129 HPIMNAGNGAGEHPTQALLDILTIHAELGAVDGITIALIGDLKKGRTVHSLLKLLTHNFA 188
Query: 181 --DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHD-PVKAVKDADVIYTD------V 231
V + P G E +V++ + + G + E + V D DV+Y
Sbjct: 189 LRKVYLIAPAGLEMPAEVLEHVATDVQKRGITMEQACGLTPEVVADCDVLYATRLQKERF 248
Query: 232 WASMGQEAEAEERRKIFR-PFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSV 290
AS +A+A + + +++K + HAK + MH LP R +E++ D+ D P +
Sbjct: 249 VASTAGDADAMAAFEASKASLRIDKARLAHAKAKMIVMHPLP--RVDELSTDIDDDPRAG 306
Query: 291 VWDEAENRLHAQKAVLALLL 310
+ + L + A+L +L
Sbjct: 307 YFRQMRYGLFMRMAILFSVL 326
>pir||H83595 aspartate carbamoyltransferase PA0402 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9946256|gb|AAG03791.1|AE004477_8 (AE004477)
aspartate carbamoyltransferase [Pseudomonas aeruginosa]
Length = 334
Score = 108 bits (267), Expect = 9e-23
Identities = 97/311 (31%), Positives = 145/311 (46%), Gaps = 20/311 (6%)
Query: 15 DYTPEEIWT-ILETA-KMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAMAHLG 72
D P E+ T IL+TA L++ + K LL GKT+ +F + STRTR +FE+A L
Sbjct: 24 DGLPRELLTEILDTADSFLEVGARAVKKVPLLRGKTVCNVFFENSTRTRTTFELAAQRLS 83
Query: 73 GHALYLNAQDLQLRRGETIADTARVL-SRYVDAIMARVYDHKDVEDLAKYAS--VPVING 129
+ LN +GET+ DT R L + D + R D +A++ S V VING
Sbjct: 84 ADVISLNVSTSSTSKGETLTDTLRNLEAMAADMFVVRHSDSGAAHFIAEHVSPNVAVING 143
Query: 130 LSD-FSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGA-DVVVA 185
+HP Q + D +TI KG + + V VGD + VA S M+A LG D+ V
Sbjct: 144 GDGRHAHPTQGMLDMLTIRRHKGNFEQLSVAIVGDILHSRVARSNMLALKTLGCPDIRVI 203
Query: 186 TPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDAD-VIYTDVWASMGQEAEAEER 244
P P I EQ + + + +KD D VI + Q
Sbjct: 204 APRTLLP----IGLEEQYGV------RVFTNADEGLKDVDVVIMLRLQRERMQGGLLPSE 253
Query: 245 RKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKA 304
+ F+ + + + +K AKPD + MH P +RG E+ V D SV+ ++ + + A
Sbjct: 254 GEFFKLYGLTEKRLKLAKPDAIVMHPGPINRGVEIESAVADGAQSVILNQVTYGIAIRMA 313
Query: 305 VLALLLGGVKT 315
VL++ + G T
Sbjct: 314 VLSMAMSGQNT 324
>sp|Q59653|PYRB_PSEAE ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE TRANSCARBAMYLASE)
(ATCASE) >gi|309885|gb|AAA25976.1| (L19649) 'aspartate
transcarbamoylase' [Pseudomonas aeruginosa]
Length = 334
Score = 108 bits (266), Expect = 1e-22
Identities = 97/311 (31%), Positives = 145/311 (46%), Gaps = 20/311 (6%)
Query: 15 DYTPEEIWT-ILETA-KMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAMAHLG 72
D P E+ T IL+TA L++ + K LL GKT+ +F + STRTR +FE+A L
Sbjct: 24 DGLPRELLTEILDTADSFLEVGARAVKKVPLLRGKTVCNVFFENSTRTRTTFELAAQRLS 83
Query: 73 GHALYLNAQDLQLRRGETIADTARVL-SRYVDAIMARVYDHKDVEDLAKYAS--VPVING 129
+ LN +GET+ DT R L + D + R D +A++ S V VING
Sbjct: 84 ADVISLNVSTSSTSKGETLTDTLRNLEAMAADMFVVRHSDSGAAHFIAEHVSPNVAVING 143
Query: 130 LSD-FSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGA-DVVVA 185
+HP Q + D +TI KG + + V VGD + VA S M+A LG D+ V
Sbjct: 144 GDGRHAHPTQGMLDMLTIRRHKGNFEQLSVAIVGDILHSRVARSNMLALKTLGCPDIRVI 203
Query: 186 TPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDAD-VIYTDVWASMGQEAEAEER 244
P P I EQ + + + +KD D VI + Q
Sbjct: 204 APATLLP----IGLEEQYGV------RVFTNADEGLKDVDVVIMLRLQRERMQGGLLPSE 253
Query: 245 RKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKA 304
+ F+ + + + +K AKPD + MH P +RG E+ V D SV+ ++ + + A
Sbjct: 254 GEFFKLYGLTEKRLKLAKPDAIVMHPGPINRGVEIESAVADGAQSVILNQVTYGIAIRMA 313
Query: 305 VLALLLGGVKT 315
VL++ + G T
Sbjct: 314 VLSMAMSGQNT 324
>sp|P96079|PYRB_THEAQ ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE TRANSCARBAMYLASE)
(ATCASE) >gi|1684759|emb|CAA70729.1| (Y09536) aspartate
carbamoyltransferase (ATCase) [Thermus aquaticus]
Length = 301
Score = 107 bits (265), Expect = 2e-22
Identities = 94/310 (30%), Positives = 143/310 (45%), Gaps = 18/310 (5%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLK-IWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEV 66
R LL Q +T E+ ++L+TA++++ + ++ K L+G T+A +F +PSTRTR+SFE+
Sbjct: 2 RHLLDFQGWTRPEVESLLDTARVMREVLERPVKKVPALQGFTVATVFFEPSTRTRISFEL 61
Query: 67 AMAHLGGHALYLNAQDLQLRRGETIADTARVLSRY-VDAIMARVYDHKDVEDLAKYASVP 125
A + + AQ L++GE+ DT L VDA + R ++
Sbjct: 62 AARRMSADVVSFAAQTSSLQKGESYKDTLLTLEAMGVDAYVIRADSAGVPHQATRWVKGA 121
Query: 126 VINGLSD-FSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGADV 182
VING +HP QAL D T+ E GT++G KV VGD + VA S LGA V
Sbjct: 122 VINGGDGRRAHPTQALLDAYTLLEALGTLEGKKVAIVGDILHSRVARSNAELLPLLGAQV 181
Query: 183 VVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAE 242
A P P +S L +A+++AD + EA
Sbjct: 182 FCAGPPSLLP-------------QSLPGAHLTPRLEEALEEADAVMVLRLQKERMEAGLV 228
Query: 243 ERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQ 302
+QV + + AKP +H P +R E+ + DS S+V + +N + +
Sbjct: 229 HLEDYIARYQVTEKRLALAKPQAPLLHPGPMNRDVELEGTLADSARSLVNRQVQNGVAVR 288
Query: 303 KAVLALLLGG 312
AVL LL G
Sbjct: 289 MAVLYHLLVG 298
>gb|AAG20942.1| (AE005160) aspartate carbamoyltransferase catalytic subunit; PyrB
[Halobacterium sp. NRC-1]
Length = 341
Score = 107 bits (265), Expect = 2e-22
Identities = 79/276 (28%), Positives = 138/276 (49%), Gaps = 14/276 (5%)
Query: 45 EGKTLAMIFQKPSTRTRVSFEVAMAHLGGHALYLNAQDLQ-LRRGETIADTARVLSRYVD 103
E L ++F +PSTRT++SF+ AM LGG + + + D +++GET+ADT RV+ Y D
Sbjct: 70 ENTVLGLLFFEPSTRTKMSFDTAMKRLGGDIVDMGSVDSSSVKKGETLADTVRVIEGYAD 129
Query: 104 AIMARVYDHKDVEDLAKYASVPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVG 162
A++ R + + +++ VP++N G HP Q L D TI E G ++ + + +G
Sbjct: 130 ALVLRHPNQGAAQMASEFVDVPLLNAGDGAGHHPTQTLLDLYTIRENAG-LEDLTIGIMG 188
Query: 163 D--GNNVAHSLMIAGTKLGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKA 220
D HSL A T D +PE + V+ EQ + + D
Sbjct: 189 DLKYGRTVHSLSRALTNFDVDQHFISPESLQLPRDVVYDLEQESGTRVREHDSFED---V 245
Query: 221 VKDADVIYTDVWASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVT 280
+ + D++Y + + E +K+ +Q+ ++ AK D MH LP R +E+
Sbjct: 246 LPELDILYV-TRIQRERFPDENEYQKVAGEYQLTATHLEAAKDDLTIMHPLP--RVDEIA 302
Query: 281 DDVIDSPNSVVWDEAENRLHAQKAVLALLL---GGV 313
++ D+ ++ +++A N + + A+L L+L GGV
Sbjct: 303 PEIDDTDHAAYFEQAHNGVPVRMALLDLVLSADGGV 338
>sp|Q09794|PYR1_SCHPO URA1 PROTEIN [INCLUDES: GLUTAMINE-DEPENDENT CARBAMOYL-PHOSPHATE
SYNTHASE ; ASPARTATE CARBAMOYLTRANSFERASE ]
>gi|2130327|pir||S62450 hypothetical protein SPAC22G7.06c
- fission yeast (Schizosaccharomyces pombe)
>gi|7436765|pir||T11616 carbamoyl-phosphate synthase
(glutamine-hydrolyzing) (EC 6.3.5.5) - fission yeast
(Schizosaccharomyces pombe) >gi|1009456|emb|CAA91130.1|
(Z54328) ura1 protein contains: glutamine-dependent
carbamoyl-phosphatesynthase [Schizosaccharomyces pombe]
Length = 2244
Score = 106 bits (262), Expect = 4e-22
Identities = 84/311 (27%), Positives = 143/311 (45%), Gaps = 10/311 (3%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
+ ++ + T ++ + A ++I + L GK L +F +PSTRT SF+ A
Sbjct: 1937 KHIISVHQVTRSDLHVLFAIAHQMRIIVERQGVIDLCYGKLLCTMFFEPSTRTSSSFDAA 1996
Query: 68 MAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVI 127
M LGG + + A + +GE++ADT R L Y DAI+ R + A ++ VP+I
Sbjct: 1997 MQRLGGKVVAVTASASSVNKGESLADTIRTLGCYGDAIVLRHPSIESARIAANFSPVPII 2056
Query: 128 N-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGADVVV 184
N G HP QA D TI E+ G++ G+ + ++GD HSL ++ +
Sbjct: 2057 NGGNGSKEHPTQAFLDLYTIREELGSVNGLTITFIGDLKYGRTVHSLARLLAFWHVELHL 2116
Query: 185 ATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEER 244
+PE + V N EL + V +DV+Y + A +E
Sbjct: 2117 VSPEQLALPDDVKDDIRANGLNFIEHRELTKE---VVAQSDVLYC-TRVQKERFASVDEY 2172
Query: 245 RKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDV-IDSPNSVVWDEAENRLHAQK 303
K+ F V+ ++ AK + MH LP R E++++V D + + + L+ +
Sbjct: 2173 EKLKDSFIVDNSVLASAKSHCIVMHPLP--RNREISEEVDFDQRRAAYFRQMRYGLYIRM 2230
Query: 304 AVLALLLGGVK 314
A+LA ++G +
Sbjct: 2231 ALLACVMGATE 2241
>pir||T30522 aspartate carbamoyltransferase (EC 2.1.3.2) - Trypanosoma cruzi
>gi|4210457|dbj|BAA74525.1| (AB017765) ACTase
[Trypanosoma cruzi]
Length = 326
Score = 106 bits (262), Expect = 4e-22
Identities = 79/317 (24%), Positives = 144/317 (44%), Gaps = 14/317 (4%)
Query: 2 VVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTR 61
V SLKG+ + + ++ +I+ ++ A ++ G+ LL+G+ + +F + S+RT
Sbjct: 7 VASLKGKSITSAEQFSRADIYALIHLASAMQRKIDAGEVLNLLQGRIMTPLFFEDSSRTF 66
Query: 62 VSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKY 121
SF AM LGG + + + +GET+ADT R L Y D ++ R +E+
Sbjct: 67 SSFCAAMIRLGGSVVNFKVEASSINKGETLADTIRTLDSYSDVLVMRHPRQDAIEEALSV 126
Query: 122 ASVPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD---GNNVAHSLMIAGTK 177
A P++N G HP QAL D +TI + G++ G+ + +GD G V L +
Sbjct: 127 AQHPILNAGNGAGEHPTQALLDTLTIHSELGSVDGITIALIGDLKMGRTVHSLLKLLVRN 186
Query: 178 LGAD-VVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPV-KAVKDADVIYTD----- 230
V + P+ + + V++ + A G H + ++ +DV+YT
Sbjct: 187 FSIKCVFLVAPDALQMPQDVLEPLQHEIATKGVIIHRTHALTDEVMQKSDVLYTTRLQKE 246
Query: 231 -VWASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNS 289
AS +A A + ++ ++ AK + MH LP R +E++ V P +
Sbjct: 247 RFMASTSDDAAALQSFAAKTDITIDAARIRLAKEKMIVMHPLP--RNDELSTTVDADPRA 304
Query: 290 VVWDEAENRLHAQKAVL 306
+ + + + A+L
Sbjct: 305 AYFRQMRYGMFMRMAIL 321
>dbj|BAA22792.1| (AB007852) aspartate carbamoyltransferase [Trypanosoma cruzi]
Length = 326
Score = 105 bits (260), Expect = 6e-22
Identities = 79/317 (24%), Positives = 144/317 (44%), Gaps = 14/317 (4%)
Query: 2 VVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTR 61
V SLKG+ + + ++ +I+ ++ A ++ G+ LL+G+ + +F + S+RT
Sbjct: 7 VASLKGKSITSAEQFSRADIYALIHLASAMQRKIDAGEVLNLLQGRIMTPLFFEDSSRTF 66
Query: 62 VSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKY 121
SF AM LGG + + + +GET+ADT R L Y D ++ R +E+
Sbjct: 67 SSFCAAMIRLGGSVVNFKVEASSINKGETLADTIRTLDSYSDVLVMRHPRQDAIEEALSV 126
Query: 122 ASVPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD---GNNVAHSLMIAGTK 177
A P++N G HP QAL D +TI + G++ G+ + +GD G V L +
Sbjct: 127 AQHPILNAGNGAGEHPTQALLDTLTIHSELGSVDGITIALIGDLKMGRTVHSLLKLLVRN 186
Query: 178 LGAD-VVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPV-KAVKDADVIYTD----- 230
V + P+ + + V++ + A G H + ++ +DV+YT
Sbjct: 187 FSIKCVFLVAPDALQMPQDVLEPLQHEIATKGVIIHRTHALTDEVMQKSDVLYTTRLQKE 246
Query: 231 -VWASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNS 289
AS +A A + ++ ++ AK + MH LP R +E++ V P +
Sbjct: 247 RFMASTSDDAAALQSFAAKADITIDAARMRLAKEKMIVMHPLP--RNDELSTTVDADPRA 304
Query: 290 VVWDEAENRLHAQKAVL 306
+ + + + A+L
Sbjct: 305 AYFRQMRYGMFMRMAIL 321
>gb|AAG15558.1| (AY007523) aspartate carbamoyl transferase PyrB [Pseudomonas
fluorescens]
Length = 334
Score = 105 bits (260), Expect = 6e-22
Identities = 93/314 (29%), Positives = 146/314 (45%), Gaps = 26/314 (8%)
Query: 11 LCLQDYTPEEIWTILETA-KMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAMA 69
L L E + IL+TA L++ + K LL GKT+ +F + STRTR +FE+A
Sbjct: 22 LSLDGLRRELLTEILDTADSFLEVGARAVKKVPLLRGKTVCNVFFENSTRTRTTFELAAQ 81
Query: 70 HLGGHALYLNAQDLQLRRGETIADTARVL-SRYVDAIMARVYDHKDVEDLAKYA--SVPV 126
L + LN +GET+ DT R L + D + R D +A++ V +
Sbjct: 82 RLSADVITLNVSTSSASKGETLLDTLRNLEAMAADMFVVRHGDSGAAHFIAEHVCPQVAI 141
Query: 127 INGLSD-FSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGA-DV 182
ING +HP Q + D +TI KG+ + + V VGD + VA S M+A LG D+
Sbjct: 142 INGGDGRHAHPTQGMLDMLTIRRHKGSFENLSVAIVGDILHSRVARSNMLALKTLGCPDI 201
Query: 183 VVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA- 241
V P+ P E G ++ D + +KD DV+ + + +E
Sbjct: 202 RVIAPKTLLP----------IGVEQYG-VKVYTDMTEGLKDVDVV---IMLRLQRERMTG 247
Query: 242 ---EERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENR 298
+ +R F + + AKPD + MH P +RG E+ V D P+SV+ ++
Sbjct: 248 GLLPSEGEFYRLFGLTTARLAGAKPDAIVMHPGPINRGVEIESAVADGPHSVILNQVTYG 307
Query: 299 LHAQKAVLALLLGG 312
+ + AVL++ + G
Sbjct: 308 IAIRMAVLSMAMSG 321
>gb|AAA24476.1| (K01472) aspartate transcarbamoylase catalytic chain (pyrB)
[Escherichia coli]
Length = 311
Score = 104 bits (258), Expect = 1e-21
Identities = 92/318 (28%), Positives = 155/318 (47%), Gaps = 21/318 (6%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
M L + ++ + D + +++ +L TA LK LL+ K +A F + STRT
Sbjct: 1 MANPLYQKHIISINDLSRDDLNLVLATAAKLKA----NPQPELLKHKVIASCFFEASTRT 56
Query: 61 RVSFEVAMAHLGGHAL-YLNAQDLQL-RRGETIADTARVLSRYVDAIMARVYDHKDVEDL 118
R+SFE +M LG + + ++ + L ++GET+ADT V+S YVDAI+ R + + L
Sbjct: 57 RLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDAIVMR-HPQEGAARL 115
Query: 119 AKYAS--VPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMI 173
A S VPV+N G HP Q L D TI E +G + + V VGD HSL
Sbjct: 116 ATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETEGRLDNLHVAMVGDLKYGRTVHSLTQ 175
Query: 174 AGTKL-GADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVW 232
A K G P+ + ++ + E G ++ L + + + D++Y +
Sbjct: 176 ALAKFDGNRFYFIAPDALAMPQYILDMLD----EKGIAWSLHSSIEEVMAEVDILY--MT 229
Query: 233 ASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVW 292
+ + E + F + + +AK + +H LP R +E+ DV +P++ +
Sbjct: 230 RVQKERLDPSEYANVKAQFVLRASDLHNAKANMKVLHPLP--RVDEIATDVDKTPHAWYF 287
Query: 293 DEAENRLHAQKAVLALLL 310
+A N + A++A+LAL+L
Sbjct: 288 QQAGNGIFARQALLALVL 305
>sp|P00479|PYRB_ECOLI ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN (ASPARTATE
TRANSCARBAMYLASE) (ATCASE) >gi|7427896|pir||DTECC
aspartate carbamoyltransferase (EC 2.1.3.2) catalytic
chain - Escherichia coli (strain K-12)
>gi|8569590|pdb|1EKX|A Chain A, The Isolated,
Unregulated Catalytic Trimer Of Aspartate
Transcarbamoylase Complexed With Bisubstrate Analog Pala
(N (Phosphonacetyl)-L-Aspartate) >gi|8569591|pdb|1EKX|B
Chain B, The Isolated, Unregulated Catalytic Trimer Of
Aspartate Transcarbamoylase Complexed With Bisubstrate
Analog Pala (N (Phosphonacetyl)-L-Aspartate)
>gi|8569592|pdb|1EKX|C Chain C, The Isolated,
Unregulated Catalytic Trimer Of Aspartate
Transcarbamoylase Complexed With Bisubstrate Analog Pala
(N (Phosphonacetyl)-L-Aspartate)
>gi|2367364|gb|AAC77202.1| (AE000495) aspartate
carbamoyltransferase, catalytic subunit [Escherichia
coli K12]
Length = 311
Score = 104 bits (258), Expect = 1e-21
Identities = 92/318 (28%), Positives = 155/318 (47%), Gaps = 21/318 (6%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
M L + ++ + D + +++ +L TA LK LL+ K +A F + STRT
Sbjct: 1 MANPLYQKHIISINDLSRDDLNLVLATAAKLKA----NPQPELLKHKVIASCFFEASTRT 56
Query: 61 RVSFEVAMAHLGGHAL-YLNAQDLQL-RRGETIADTARVLSRYVDAIMARVYDHKDVEDL 118
R+SFE +M LG + + ++ + L ++GET+ADT V+S YVDAI+ R + + L
Sbjct: 57 RLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDAIVMR-HPQEGAARL 115
Query: 119 AKYAS--VPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMI 173
A S VPV+N G HP Q L D TI E +G + + V VGD HSL
Sbjct: 116 ATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAMVGDLKYGRTVHSLTQ 175
Query: 174 AGTKL-GADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVW 232
A K G P+ + ++ + E G ++ L + + + D++Y +
Sbjct: 176 ALAKFDGNRFYFIAPDALAMPQYILDMLD----EKGIAWSLHSSIEEVMAEVDILY--MT 229
Query: 233 ASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVW 292
+ + E + F + + +AK + +H LP R +E+ DV +P++ +
Sbjct: 230 RVQKERLDPSEYANVKAQFVLRASDLHNAKANMKVLHPLP--RVDEIATDVDKTPHAWYF 287
Query: 293 DEAENRLHAQKAVLALLL 310
+A N + A++A+LAL+L
Sbjct: 288 QQAGNGIFARQALLALVL 305
>gb|AAA97142.1| (U14003) aspartate carbomoyltransferase catalytic subunit
[Escherichia coli]
Length = 311
Score = 104 bits (257), Expect = 1e-21
Identities = 92/318 (28%), Positives = 155/318 (47%), Gaps = 21/318 (6%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
M L + ++ + D + +++ +L TA LK LL+ K +A F + STRT
Sbjct: 1 MANPLYQKHIISINDLSRDDLNLVLATAAKLKA----NPQPELLKHKVIASCFFEASTRT 56
Query: 61 RVSFEVAMAHLGGHAL-YLNAQDLQL-RRGETIADTARVLSRYVDAIMARVYDHKDVEDL 118
R+SFE +M LG + + ++ + L ++GET+ADT V+S YVDAI+ R + + L
Sbjct: 57 RLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDAIVMR-HPQEGAARL 115
Query: 119 AKYAS--VPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMI 173
A S VPV+N G HP Q L D TI E +G + + V VGD HSL
Sbjct: 116 ATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAMVGDLKYGRTVHSLTQ 175
Query: 174 AGTKL-GADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVW 232
A K G P+ + ++ + E G ++ L + + + D++Y +
Sbjct: 176 ALAKFDGNRFYFIAPDALAMRQYILDMLD----EKGIAWSLHSSIEEVMAEVDILY--MT 229
Query: 233 ASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVW 292
+ + E + F + + +AK + +H LP R +E+ DV +P++ +
Sbjct: 230 RVQKERLDPSEYANVKAQFVLRASDLHNAKANMKVLHPLP--RVDEIATDVDKTPHAWYF 287
Query: 293 DEAENRLHAQKAVLALLL 310
+A N + A++A+LAL+L
Sbjct: 288 QQAGNGIFARQALLALVL 305
>sp|Q59711|PYRB_PSEPU ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE TRANSCARBAMYLASE)
(ATCASE) >gi|1360919|pir||A56144 aspartate
carbamoyltransferase (EC 2.1.3.2) 36k catalytic chain -
Pseudomonas putida (strain PpN-1)
>gi|151521|gb|AAD15279.1| (M97253) aspartate
carbamoyltransferase [Pseudomonas putida]
Length = 334
Score = 104 bits (256), Expect = 2e-21
Identities = 96/312 (30%), Positives = 147/312 (46%), Gaps = 29/312 (9%)
Query: 15 DYTPEEIWT-ILETA-KMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAMAHLG 72
D P E+ T IL+TA L++ + K LL GKT+ +F + STRTR +FE+A L
Sbjct: 25 DGLPRELLTEILDTADSFLEVGARAVKKVPLLRGKTVCNVFFENSTRTRTTFELAAQRLS 84
Query: 73 GHALYLNAQDLQLRRGETIADTARVL-SRYVDAIMARVYDHKDVEDLAKYA--SVPVING 129
+ LN +GET+ DT R L + D + R D +A++ V VING
Sbjct: 85 ADVISLNVSTSSTSKGETLFDTLRNLEAMAADMFVVRHSDSGAAHFIAEHVCPDVAVING 144
Query: 130 LSD-FSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGADVVVAT 186
+HP Q + D +TI KG+ + + V VGD + VA S M+A LG
Sbjct: 145 GDGRHAHPTQGMLDMLTIRRHKGSFENLSVAIVGDILHSRVARSDMLALKALGC------ 198
Query: 187 PEGYEPDEKVI--KWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEA--- 241
PD +VI K E G ++ D + +KD DV+ + + +E A
Sbjct: 199 -----PDIRVIGPKTLIPIGIEQYG-VKVYTDLAEGLKDVDVV---IMLRLQRERMAGGL 249
Query: 242 -EERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLH 300
+ +R F + + AKPD + MH P +RG E+ V D +SV+ ++ +
Sbjct: 250 LPSEGEFYRLFGLTTARLACAKPDAIVMHPGPINRGVEIESAVADGKHSVILNQVTYGIA 309
Query: 301 AQKAVLALLLGG 312
+ AVL++ + G
Sbjct: 310 VRMAVLSMAMSG 321
>pir||S35212 aspartate carbamoyltransferase (EC 2.1.3.2) - tomato (fragment)
Length = 268
Score = 104 bits (256), Expect = 2e-21
Identities = 86/277 (31%), Positives = 131/277 (47%), Gaps = 20/277 (7%)
Query: 46 GKTLAMIFQKPSTRTRVSFEVAMAHLGGHALYL-NAQDL-QLRRGETIADTARVLSRYVD 103
G +A +F +PSTRTR+SFE +M LGG L NA++ +GET+ DT R + Y D
Sbjct: 1 GYLMATLFYEPSTRTRLSFESSMKRLGGEVLTTENAREFSSAAKGETLEDTIRTVEGYSD 60
Query: 104 AIMARVYDHKDVEDLAKYASVPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVG 162
I+ R ++ A AS+P+IN G HP QAL D TI + G + G+ + VG
Sbjct: 61 IIVMRHFESGAARRAALTASIPIINAGDGPGQHPTQALLDVYTIGREIGKLDGINIALVG 120
Query: 163 D---GNNVAHSLMIAGTKLGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVK 219
D G V + + +P+ + + + + G +E D ++
Sbjct: 121 DLAYGRTVRSLAHLLALYKDVKIYFVSPDVVKMKDDI----KDYLTSMGVRWEESADLIE 176
Query: 220 AVKDADVIY-TDVWAS-MGQEAE--AEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHR 275
DV+Y T + G+ + E R K V + KHA + MH LP R
Sbjct: 177 VASKCDVVYQTRIQRERFGERVDLYEEARGKYIVDMSVVNAMQKHA----VVMHPLP--R 230
Query: 276 GEEVTDDVIDSPNSVVWDEAENRLHAQKAVLALLLGG 312
+E+T DV P + + +A+N L+ + A+L LLL G
Sbjct: 231 LDEITVDVDGDPRAAYFRQAKNGLYIRMALLKLLLLG 267
>sp|P08420|PYRB_SALTY ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN (ASPARTATE
TRANSCARBAMYLASE) (ATCASE)
Length = 310
Score = 103 bits (255), Expect = 2e-21
Identities = 93/318 (29%), Positives = 154/318 (48%), Gaps = 22/318 (6%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
M L + ++ + D + +++ +L TA LK LL+ K +A F + STRT
Sbjct: 1 MANPLYQKHIISINDLSRDDLNLVLATAAKLKA----NPQPELLKHKVIASCFFEASTRT 56
Query: 61 RVSFEVAMAHLGGHAL-YLNAQDLQL-RRGETIADTARVLSRYVDAIMARVYDHKDVEDL 118
R+SFE +M LG + + ++ + L ++GET+ADT V+S YVDAI+ R + + L
Sbjct: 57 RLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDAIVMR-HPQEGAARL 115
Query: 119 AKYAS--VPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMI 173
A S VPV+N G HP Q L D TI E +G + + + VGD HSL
Sbjct: 116 ATEFSGQVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHIAMVGDLKYGRTVHSLAQ 175
Query: 174 AGTKL-GADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVW 232
K G P+ + ++ + E G ++ L + + D D++Y +
Sbjct: 176 TLAKFSGNRFYFIAPDALAMPQYILDMLD----EKGMAWSLHGSIEEVMADVDILY--MT 229
Query: 233 ASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVW 292
+ + E + F + DL A+ + +H LP R +E+T DV +P++ +
Sbjct: 230 RVQKERLDPSEYANVKAQFVLRPDL-NGARENMKVLHPLP--RIDEITTDVDKTPHAWYF 286
Query: 293 DEAENRLHAQKAVLALLL 310
+A N + A +A+LAL+L
Sbjct: 287 QQAGNGIFAAQALLALVL 304
>pir||S42709 aspartate carbamoyltransferase (EC 2.1.3.2) - tomato (fragment)
>gi|397385|emb|CAA52201.1| (X74072) aspartate
carbamoyltransferase [Lycopersicon esculentum]
Length = 268
Score = 103 bits (254), Expect = 3e-21
Identities = 86/277 (31%), Positives = 129/277 (46%), Gaps = 20/277 (7%)
Query: 46 GKTLAMIFQKPSTRTRVSFEVAMAHLGGHALYL-NAQDL-QLRRGETIADTARVLSRYVD 103
G +A +F +PSTRTR+SFE +M LGG L NA++ +GET+ DT R + Y D
Sbjct: 1 GYLMATLFYEPSTRTRLSFESSMKRLGGEVLTTENAREFSSAAKGETLEDTIRTVEGYSD 60
Query: 104 AIMARVYDHKDVEDLAKYASVPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVG 162
I+ R ++ A AS+P+IN G HP QAL D TI + G + G+ + VG
Sbjct: 61 IIVMRHFESGAARRAALSASIPIINAGDGPGQHPTQALLDVYTIGREIGKLDGINIALVG 120
Query: 163 D---GNNVAHSLMIAGTKLGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVK 219
D G V + + +P+ + + + + G +E D ++
Sbjct: 121 DLAYGRTVRSLAHLLALYKDVKIYFVSPDVVKMKDDI----KDYLTSMGVRWEESADLIE 176
Query: 220 AVKDADVIY-TDVWASMGQEAEA---EERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHR 275
DV+Y T + E A E R K + KHA + MH LP R
Sbjct: 177 VASKCDVVYQTRIQRERFGERVALYEEARGKYIVDMSAVNAMQKHA----VVMHPLP--R 230
Query: 276 GEEVTDDVIDSPNSVVWDEAENRLHAQKAVLALLLGG 312
+E+T DV P + + +A+N L+ + A+L LLL G
Sbjct: 231 LDEITVDVDGDPRAAYFRQAKNGLYIRMALLKLLLLG 267
>sp|P41008|PYRB_BACCL ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE TRANSCARBAMYLASE)
(ATCASE) >gi|312440|emb|CAA51736.1| (X73308) aspartate
carbamoyltransferase [Bacillus caldolyticus]
Length = 308
Score = 102 bits (252), Expect = 5e-21
Identities = 82/311 (26%), Positives = 150/311 (47%), Gaps = 29/311 (9%)
Query: 10 LLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAMA 69
L L + +EI +L+ A+ + G+ R +A +F +PSTRT+ SFE+A
Sbjct: 4 LFALSELPLDEIHRLLDEAERFRS----GRIWRPAAPMYVANLFFEPSTRTKCSFEMAER 59
Query: 70 HLGGHALYLNAQDLQLRRGETIADTARVLSRY-VDAIMARVYDHKDVEDLAKYASVPVIN 128
LG H + + + +++GET+ DT R L VDA++ R ++ E L +P+IN
Sbjct: 60 KLGLHVIPFDPERSSVQKGETLYDTVRTLEAIGVDAVVIRHHEDAYFEALRHAVGIPIIN 119
Query: 129 -GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGADVVVA 185
G HP Q+L D +TI ++ G G+ V +GD + VA S T+LGA+V+ +
Sbjct: 120 AGDGCGHHPTQSLLDLLTIRQEFGAFTGLTVAIIGDIRHSRVARSNAEVLTRLGANVLFS 179
Query: 186 TPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAE--- 242
PE +W ++ + + +A+ ADV+ + + E AE
Sbjct: 180 GPE---------EWKDET-----NPYGTYVEVDEAIARADVV---MLLRIQHERHAETMG 222
Query: 243 -ERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHA 301
+ + + + + + K + +H P +RG E+ +++++ S ++ + EN ++
Sbjct: 223 LTKEEYHARYGLTLERARRMKSGAIILHPAPVNRGVEIASELVEAKASRIFKQMENGVYV 282
Query: 302 QKAVLALLLGG 312
+ AVL + G
Sbjct: 283 RMAVLKRAMEG 293
>pir||I40166 aspartate carbamoyltransferase (EC 2.1.3.2) - Bacillus caldolyticus
Length = 308
Score = 102 bits (252), Expect = 5e-21
Identities = 82/311 (26%), Positives = 150/311 (47%), Gaps = 29/311 (9%)
Query: 10 LLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAMA 69
L L + +EI +L+ A+ + G+ R +A +F +PSTRT+ SFE+A
Sbjct: 4 LFALSELPLDEIHRLLDEAERFRS----GRIWRPAAPMYVANLFFEPSTRTKCSFEMAER 59
Query: 70 HLGGHALYLNAQDLQLRRGETIADTARVLSRY-VDAIMARVYDHKDVEDLAKYASVPVIN 128
LG H + + + +++GET+ DT R L VDA++ R ++ E L +P+IN
Sbjct: 60 KLGLHVIPFDPERSSVQKGETLYDTVRTLEAIGVDAVVIRHHEDAYFEALRHAVGIPIIN 119
Query: 129 -GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGADVVVA 185
G HP Q+L D +TI ++ G G+ V +GD + VA S T+LGA+V+ +
Sbjct: 120 AGDGCGHHPTQSLLDLLTIRQEFGAFTGLTVAIIGDIRHSRVARSNAEVLTRLGANVLFS 179
Query: 186 TPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAE--- 242
PE +W ++ + + +A+ ADV+ + + E AE
Sbjct: 180 GPE---------EWKDET-----NPYGTYVEVDEAIARADVV---MLLRIQHERHAETMG 222
Query: 243 -ERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHA 301
+ + + + + + K + +H P +RG E+ +++++ S ++ + EN ++
Sbjct: 223 LTKEEYHARYGLTLERARRMKSGAIILHPAPVNRGVEIASELVEAKASRIFKQMENGVYV 282
Query: 302 QKAVLALLLGG 312
+ AVL + G
Sbjct: 283 RMAVLKRAMEG 293
>pir||T20371 hypothetical protein D2085.1 - Caenorhabditis elegans
>gi|3875382|emb|CAA91059.1| (Z54284) contains similarity
to Pfam domain: PF00117 (Glutamine amidotransferase
class-I), Score=244.1, E-value=6.1e-70, N=1; PF00185
(Aspartate/ornithine carbamoyltransferase), Score=397.5,
E-value=4.1e-116, N=1; PF00289 (Carbamoyl-phosphate
synthase >
Length = 2198
Score = 102 bits (252), Expect = 5e-21
Identities = 88/327 (26%), Positives = 149/327 (44%), Gaps = 26/327 (7%)
Query: 5 LKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKP-HRLLEGKTLAMIFQKPSTRTRVS 63
L ++ + ++ +I I E A K + G P +L GK L +F + STRT S
Sbjct: 1874 LLAKNCISVKHLDKGQINRIFELADRYKHDVEKGHPLTHILNGKVLVNLFYEVSTRTSCS 1933
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
F AM LGG + +++Q +++GET+ DT +VL Y D ++ R ++ + A+
Sbjct: 1934 FSAAMQRLGGSVISVDSQSSSVQKGETLEDTVQVLGSYGDILVLRSNENGAADRAARVCD 1993
Query: 124 VPVINGLSDF-SHPCQALADYMTIWEKKGTIKGVKVVYVGDGNN--VAHSL--MIAGTKL 178
PVING HP QAL D TI ++ GT+ G+ + VGD N HSL ++ K
Sbjct: 1994 QPVINGGDGTGEHPTQALLDVYTIRQEMGTVNGLTIALVGDLKNGRTVHSLAKLLCLYKD 2053
Query: 179 GADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQE 238
VA E ++V+ + + F L + + DV+Y +
Sbjct: 2054 ITLHYVAPSTELEMPQEVLDYVSSKSNFVQKKFTSL---AEGINHVDVVYV-TRIQKERF 2109
Query: 239 AEAEERRKIFRPFQVNKDLVKHAKPDY--------------MFMHCLPAHRGEEVTDDVI 284
+ +E K+ + +N L+ A D + MH LP R +E+ ++
Sbjct: 2110 SSPDEYNKVKGSYVINAKLLNEAARDVEEPSSLLVPARSLPIVMHPLP--RVDEIAVELD 2167
Query: 285 DSPNSVVWDEAENRLHAQKAVLALLLG 311
+ + +A+N + + ++L+LLLG
Sbjct: 2168 HDERAAYFRQAKNGVFVRMSILSLLLG 2194
>gb|AAA24474.1| (J01670) aspartate transcarbamoylase catalytic chain [Escherichia
coli]
Length = 311
Score = 102 bits (251), Expect = 7e-21
Identities = 91/318 (28%), Positives = 154/318 (47%), Gaps = 21/318 (6%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
M L + ++ + D + +++ +L TA LK LL+ K +A F + STRT
Sbjct: 1 MANPLYQKHIISINDLSRDDLNLVLATAAKLKA----NPQPELLKHKVIASCFFEASTRT 56
Query: 61 RVSFEVAMAHLGGHAL-YLNAQDLQL-RRGETIADTARVLSRYVDAIMARVYDHKDVEDL 118
R+SF+ +M LG + + ++ + L ++GET+ADT V+S YVDAI+ R + + L
Sbjct: 57 RLSFQTSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDAIVMR-HPQEGAARL 115
Query: 119 AKYAS--VPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMI 173
A S VPV+N G HP Q L D TI E +G + + V VGD HSL
Sbjct: 116 ATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAMVGDLKYGRTVHSLTQ 175
Query: 174 AGTKL-GADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVW 232
A K G P+ + ++ + E G ++ L + + + D++Y +
Sbjct: 176 ALAKFDGNRFYFIAPDALAMPQYILDMLD----EKGIAWSLHSSIEEVMVEVDILY--MT 229
Query: 233 ASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVW 292
+ + E + F + + +AK + +H LP R +E+ DV +P++ +
Sbjct: 230 RVQKERLDPSEYANVKAQFVLRASDLHNAKANMKVLHPLP--RVDEIATDVDKTPHAWYF 287
Query: 293 DEAENRLHAQKAVLALLL 310
+A N + A +A+LAL+L
Sbjct: 288 QQAGNGIFALQALLALVL 305
>sp|P19910|PYRB_SERMA ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN (ASPARTATE
TRANSCARBAMYLASE) (ATCASE) >gi|279484|pir||OWSEAC
aspartate carbamoyltransferase (EC 2.1.3.2) catalytic
chain - Serratia marcescens >gi|398075|gb|AAA26564.1|
(J05033) aspartate transcarbamoylase [Serratia
marcescens]
Length = 306
Score = 101 bits (250), Expect = 9e-21
Identities = 92/318 (28%), Positives = 153/318 (47%), Gaps = 26/318 (8%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
M L + ++ + D + +++ +L TA LK LL+ K +A F + STRT
Sbjct: 1 MANPLYHKHIISINDLSRDDLELVLATAAGLKA----NPQPELLKHKVIASCFFEASTRT 56
Query: 61 RVSFEVAMAHLGGHAL-YLNAQDLQL-RRGETIADTARVLSRYVDAIMARVYDHKDVEDL 118
R+SFE +M LG + + + + L ++GET+ADT V+S YVDAI+ R + +
Sbjct: 57 RLSFETSMHRLGASVVGFADGSNTSLGKKGETLADTISVISTYVDAIVMR-HPQEGARMA 115
Query: 119 AKYA-SVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAG 175
++++ +VPV+N HP Q L D TI E +G + + + VGD HSL A
Sbjct: 116 SEFSGNVPVLNAGDGNQHPTQTLLDLFTIQETQGRLSNLSIAMVGDLKYGRTVHSLTQAL 175
Query: 176 TKL-GADVVVATPEGYEPDEKVIKWAEQNAAE--SGGSFELLHDPVKAVKDADVIYTDVW 232
K G P+ ++K E+ E S GS E + V + D++Y +
Sbjct: 176 AKFEGNRFYFIAPDALAMPAYILKMLEEKGIEYSSHGSIE------EVVPELDILY--MT 227
Query: 233 ASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVW 292
+ + E + F + DL A + +H LP R +E+ DV +P++ +
Sbjct: 228 RVQKERLDPSEYANVKAQFVLAADLAGAA--NLKVLHPLP--RIDEIATDVDKTPHAYYF 283
Query: 293 DEAENRLHAQKAVLALLL 310
+A N + A+ A LAL++
Sbjct: 284 QQAGNGIFARSA-LALVV 300
>gb|AAF01338.1|AF190426_2 (AF190426) aspartate transcarbamylase catalytic subunit [Erwinia
herbicola]
Length = 311
Score = 101 bits (248), Expect = 2e-20
Identities = 95/326 (29%), Positives = 153/326 (46%), Gaps = 37/326 (11%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
M L + ++ + D + EE+ L TA LK + LL+ K +A F + STRT
Sbjct: 1 MANPLYRKHIISINDLSREELELALHTAAKLKAHPQ----PELLKHKVIASCFFEASTRT 56
Query: 61 RVSFEVAMAHLGGHAL-YLNAQDLQL-RRGETIADTARVLSRYVDAIMARVYDHKDVEDL 118
R+SFE A+ LG A+ + + + L ++GET+ADT V+S YVDAI+ R + + L
Sbjct: 57 RLSFETAIHRLGASAVGFADGSNTSLGKKGETLADTISVISTYVDAIVMR-HPQEGAARL 115
Query: 119 AKYAS--VPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMI 173
A S +P++N G HP Q L D TI E + + + V VGD HSL
Sbjct: 116 ATEFSGGIPILNAGDGANQHPTQTLLDLFTIQETQSRLNQLNVAMVGDLKYGRTVHSLTQ 175
Query: 174 AGTKL-GADVVVATPEGYEP--------DEKVIKWAEQNAAESGGSFELLHDPVKAVKDA 224
A K G P+ DEK I W+ ++ E + +
Sbjct: 176 ALAKFDGNRFFFIAPDALAMPAYITDMLDEKNISWSRHDSFE------------EVMPQL 223
Query: 225 DVIYTDVWASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVI 284
D++Y + + + E + F + + A+ + +H LP R +E+T DV
Sbjct: 224 DILY--MTRVQKERLDPSEYANVKAQFILRAADLATARDNMKVLHPLP--RIDEITTDVD 279
Query: 285 DSPNSVVWDEAENRLHAQKAVLALLL 310
+P + + +A N ++A++A+LAL+L
Sbjct: 280 KTPYAWYFQQAGNGIYARQALLALVL 305
>pir||OWEBAC aspartate carbamoyltransferase (EC 2.1.3.2) catalytic chain -
Salmonella typhimurium >gi|47863|emb|CAA29129.1|
(X05641) pyrB (AA 1-311) [Salmonella typhimurium]
Length = 311
Score = 100 bits (246), Expect = 3e-20
Identities = 92/319 (28%), Positives = 154/319 (47%), Gaps = 23/319 (7%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
M L + ++ + D + +++ +L TA LK LL+ K +A F + STRT
Sbjct: 1 MANPLYQKHIISINDLSRDDLNLVLATAAKLKA----NPQPELLKHKVIASCFFEASTRT 56
Query: 61 RVSFEVAMAHLGGHAL-YLNAQDLQL-RRGETIADTARVLSRYVDAIMARVYDHKDVEDL 118
R+SFE +M LG + + ++ + L ++GET+ADT V+S YVDAI+ R + + L
Sbjct: 57 RLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDAIVMR-HPQEGAARL 115
Query: 119 AKYAS--VPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD---GNNVAHSLM 172
A S VPV+N G HP Q L D TI E +G + + + VGD G V +
Sbjct: 116 ATEFSGQVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHIAMVGDLKYGRTVHFAKP 175
Query: 173 IAGTKL-GADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDV 231
K G P+ + ++ + E G ++ L + + D D++Y +
Sbjct: 176 RTLAKFSGNRFYFIAPDALAMPQYILDMLD----EKGMAWSLHGSIEEVMADVDILY--M 229
Query: 232 WASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVV 291
+ + E + F + DL A+ + +H LP R +E+T DV +P++
Sbjct: 230 TRVQKERLDPSEYANVKAQFVLRPDL-NGARENMKVLHPLP--RIDEITTDVDKTPHAWY 286
Query: 292 WDEAENRLHAQKAVLALLL 310
+ +A N + A +A+LAL+L
Sbjct: 287 FQQAGNGIFAAQALLALVL 305
>pir||S65074 pyrimidine synthesis protein URA1 - fission yeast
(Schizosaccharomyces pombe) >gi|1154952|emb|CAA57433.1|
(X81841) carbamoyl-phosphate synthase
(glutamine-hydrolysing) [Schizosaccharomyces pombe]
Length = 2223
Score = 100 bits (246), Expect = 3e-20
Identities = 82/311 (26%), Positives = 141/311 (44%), Gaps = 10/311 (3%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
+ ++ + T ++ + A ++I + L K L +F +PSTRT SF+ A
Sbjct: 1916 KHIISVHQVTRSDLHVLFAIAHQMRIIVERQGVIDLCYEKLLCTMFFEPSTRTSSSFDAA 1975
Query: 68 MAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVI 127
M LG + + A + +GE++ADT R L Y DAI+ R + A ++ VP+I
Sbjct: 1976 MQRLGEKVVAVTASASSVNKGESLADTIRTLGCYGDAIVLRHPSIESARIAANFSPVPII 2035
Query: 128 N-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGADVVV 184
N G HP QA D TI E+ G++ G+ + ++GD HSL ++ +
Sbjct: 2036 NGGNGSKEHPTQAFLDLYTIREELGSVNGLTITFIGDLKYGRTVHSLARLLAFWHVELHL 2095
Query: 185 ATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEER 244
+PE + V N EL + V +DV+Y + A +E
Sbjct: 2096 VSPEQLALPDDVKDDIRANGLNFIEHRELTKE---VVAQSDVLYC-TRVQKERFASVDEY 2151
Query: 245 RKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDV-IDSPNSVVWDEAENRLHAQK 303
K+ F V+ ++ AK + MH LP R E++++V D + + + L+ +
Sbjct: 2152 EKLKDSFIVDNSVLASAKSHCIVMHPLP--RNREISEEVDFDQRRAAYFRQMRYGLYIRM 2209
Query: 304 AVLALLLGGVK 314
A+LA ++G +
Sbjct: 2210 ALLACVMGATE 2220
>pir||C72547 probable aspartate carbamoyltransferase catalytic chain APE1663 -
Aeropyrum pernix (strain K1) >gi|5105351|dbj|BAA80664.1|
(AP000062) 312aa long hypothetical aspartate
carbamoyltransferase catalytic chain [Aeropyrum pernix]
Length = 312
Score = 99.5 bits (244), Expect = 5e-20
Identities = 89/313 (28%), Positives = 150/313 (47%), Gaps = 17/313 (5%)
Query: 6 KGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFE 65
KGRD++ + D+T ++ + A +++ K G + L+GK +A+ F +PSTRTR+SFE
Sbjct: 11 KGRDVISITDFTRGDLELLFRQADVIE--SKAGS--KPLDGKVVALAFFEPSTRTRLSFE 66
Query: 66 VAMAHLGGHALYLNAQD-LQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASV 124
A+ LGG L ++ ++ + + +GE +ADT +L Y DAI+ R A+ A
Sbjct: 67 TAVKRLGGSTLLISGEEAISVAKGENLADTITMLDSYADAIVIRHRYEGAALYAAEVAEK 126
Query: 125 PVINGLSDFS-HPCQALADYMTIWEKKGTIKGVKVVYVGD-GNNVAHSLMIAGTKL--GA 180
PVING HP QA+ D T++ GT+ G+ +GD A S I G L
Sbjct: 127 PVINGGDGRQHHPTQAMLDLYTVYSLFGTVDGLTYGVLGDLRYGRAASSFILGLSLFNPR 186
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAE 240
V + +P +V++ E+ E L D + + DV+Y + +
Sbjct: 187 HVYLISPPQLRARREVLEALEKRGVPY-TEVERLQD---VLGELDVLYV-TRIQKERIPD 241
Query: 241 AEERRKIFRPFQVNKDLVK-HAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRL 299
E + ++V DL++ AK +H LP R +E+ V S + +A +
Sbjct: 242 PREYESLRGSYRVTLDLLESFAKESLKVLHPLP--RVDEIDFSVDSSRYQAYFTQARLGV 299
Query: 300 HAQKAVLALLLGG 312
+ A++ L++ G
Sbjct: 300 RVRMALMNLVMRG 312
>sp|P57450|PYRB_BUCAI ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN (ASPARTATE
TRANSCARBAMYLASE) (ATCASE) >gi|10039039|dbj|BAB13073.1|
(AP001119) aspartate carbamoyltransferase catalytic
chain [Buchnera sp. APS]
Length = 310
Score = 99.5 bits (244), Expect = 5e-20
Identities = 88/322 (27%), Positives = 156/322 (48%), Gaps = 35/322 (10%)
Query: 4 SLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVS 63
SL ++++ + D E+ +L + MLK K +P+ LL+ K +A F + STRTR+S
Sbjct: 4 SLYKKNIISINDLQRNELELVLNKSAMLK---KTPQPN-LLKNKVIASCFFEASTRTRLS 59
Query: 64 FEVAMAHLGGHAL-YLNAQDLQL-RRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKY 121
FE A+ LG + + + ++ L ++GET+ DT V+S YVDAI+ R A++
Sbjct: 60 FETAIYRLGASIVGFSDGNNISLEKKGETLTDTISVISSYVDAIIIRHPQEGSARLAAEF 119
Query: 122 AS-VPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTK 177
++ P+ N G HP Q L D TI E + + + + VGD HSL A K
Sbjct: 120 SNKKPIFNAGDGANQHPTQTLLDLFTIQETQNRLTQLNIAIVGDLKYGRTVHSLTQALAK 179
Query: 178 LGAD-VVVATPEGYEP--------DEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIY 228
+ +P+ + D+K I W N E + + + D++Y
Sbjct: 180 FKHNKFYFISPDALKMPNYINNMLDKKEIYWKRHNNIE------------EIISEIDILY 227
Query: 229 TDVWASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPN 288
+ + ++ E F + ++K+A+ + +H LP R +E+ DV +P
Sbjct: 228 --MTRIQKERLDSTEYANAKSKFVLRAAILKNARNNMKILHPLP--RIDEIDRDVDYTPY 283
Query: 289 SVVWDEAENRLHAQKAVLALLL 310
+ + +A N ++A++A+L+L+L
Sbjct: 284 AWYFKQAANGIYARQAILSLVL 305
>gb|AAA37009.1| (M33702) dihydroorotase synthetase complex (EC 3.5.2.3) [Cricetulus
sp.]
Length = 708
Score = 98.7 bits (242), Expect = 8e-20
Identities = 60/171 (35%), Positives = 94/171 (54%), Gaps = 3/171 (1%)
Query: 4 SLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVS 63
SL G+ +L ++ +T +++ + A L++ + + +L+GK +A +F + STRT S
Sbjct: 518 SLVGQHILSVKQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSS 577
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
F AMA LGG L + +++GE++AD+ + +S Y D ++ R VE AK+
Sbjct: 578 FAAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCR 637
Query: 124 VPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSL 171
PVIN G HP QAL D TI E+ GT+ G+ + VGD HSL
Sbjct: 638 RPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSL 688
>gb|AAA35198.1| (J04711) carbamylase phosphate synthetase-aspartate
transcarbamylase (EC 2.1.3.2) [Saccharomyces cerevisiae]
Length = 947
Score = 96.0 bits (235), Expect = 5e-19
Identities = 84/314 (26%), Positives = 145/314 (45%), Gaps = 18/314 (5%)
Query: 6 KGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFE 65
+GR +L ++ + + + A+ L+ L++G + IF +PSTRT SF
Sbjct: 641 RGRHILSIKQFKRSDFHVLFAVAQELRARVAREGVLDLMKGHVITTIFFEPSTRTCSSFI 700
Query: 66 VAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVP 125
AM LGG + +N +++GET+ D R L+ Y DAI+ R + V AKY+ VP
Sbjct: 701 AAMERLGGRIVNVNPLVSSVKKGETLQDIIRTLACYSDAIVMRHSEEMSVHIAAKYSPVP 760
Query: 126 VINGLSDFSH-PCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGADV 182
+ING + P QA D TI E+ GT+ G+ V ++GD HSL +
Sbjct: 761 IINGGNGSRELPTQAFLDLFTIREEIGTVNGITVTFMGDLKHGRTVHSLCRLLMHYQVRI 820
Query: 183 VVATPEGYEPDEKVIKWAEQNAAESG-GSFELLHDPVKAVKDADVIYTDVWASMGQEA-- 239
+ +P P+ ++ + + ++G E + + DV+Y + QE
Sbjct: 821 NLVSP----PELRLPEGLREELRKAGLLGVESIELTPHIISKTDVLY----CTRVQEERF 872
Query: 240 -EAEERRKIFRPFQVNKDLVKHAKPDYM-FMHCLPAHRGEEVTDDVIDSPNSVVWDEAEN 297
EE ++ + V+ H + M MH LP R E+ ++V + + + +
Sbjct: 873 NSPEEYARLKDTYIVDNVRSWHTQQKNMAIMHPLP--RVNEIKEEVDYDHRAAYFRQMKY 930
Query: 298 RLHAQKAVLALLLG 311
L + A+LA+++G
Sbjct: 931 GLFVRMALLAMVMG 944
>emb|CAB89871.1| (AJ132624) aspartate transcarbamoylase [Lactococcus lactis]
Length = 310
Score = 95.2 bits (233), Expect = 9e-19
Identities = 86/315 (27%), Positives = 145/315 (45%), Gaps = 27/315 (8%)
Query: 9 DLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAM-IFQKPSTRTRVSFEVA 67
+L +++ + +E+ +++ A K GK L+ +T A +F + STRT SF +A
Sbjct: 12 NLTSMENLSIDEVMGLIKRASAFKA----GKADFALDEQTFASNLFFENSTRTHHSFHIA 67
Query: 68 MAHLGGHALYLNAQDLQLRRGETIADTARVLSRY-VDAIMARVYDHKDVEDLAKYASV-- 124
LG L +AQ + +GET+ DT L VD + R E+L ++
Sbjct: 68 ERKLGLDVLEFDAQASSISKGETLYDTVLTLDALGVDICVIRSGVEHYYEELVNSDNIHC 127
Query: 125 PVINGLSDFS--HPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAGTKLGA 180
++NG D S HP Q L D MTI+E+ G +G+K+ GD + VA S M+ KLGA
Sbjct: 128 AIVNG-GDGSGQHPSQCLLDLMTIYEEFGKFEGLKIAISGDLTHSRVAKSNMMMLQKLGA 186
Query: 181 DVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADV-IYTDVWASMGQEA 239
+ P + +E + G + L + + + DV + V
Sbjct: 187 RLYFTGPAAWYSEE----------FDDYGHYANLD---RILPELDVHMLLRVQHERHDSG 233
Query: 240 EAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRL 299
E+ + F + ++ K KP + MH P +R E+ D +++SP S + + N +
Sbjct: 234 ESFSKEGYHTHFGLTQERAKMLKPTAIIMHPAPVNRDVEIADSLVESPQSRIVQQMSNGV 293
Query: 300 HAQKAVLALLLGGVK 314
+ + A+L +L G K
Sbjct: 294 YTRMAILEAILAGKK 308
>sp|O25716|PYRB_HELPY ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE TRANSCARBAMYLASE)
(ATCASE) >gi|7433607|pir||D64655 aspartate
transcarbamoylase - Helicobacter pylori (strain 26695)
>gi|2314233|gb|AAD08128.1| (AE000615) aspartate
transcarbamoylase (pyrB) [Helicobacter pylori 26695]
Length = 307
Score = 94.8 bits (232), Expect = 1e-18
Identities = 88/326 (26%), Positives = 152/326 (45%), Gaps = 45/326 (13%)
Query: 6 KGRDLLCLQDYTPEEIWTILETAKML-KIWQKIG-KPHRLLEGKTLAMIFQKPSTRTRVS 63
K R LL D + +EI +LE A + + + + + K + +F + STRT S
Sbjct: 4 KCRHLLQTSDLSLDEIKLLLEKASVYANDFNAVSLETKEKMHNKIIVALFFENSTRTVSS 63
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTAR-VLSRYVDAIMARVYDHKDVEDLAKYA 122
FE+A LG + LN Q +GET+ DT + + + DAI+ R LA+++
Sbjct: 64 FEIASLRLGAKIVKLNMQTSSASKGETLTDTFKNIHAMQPDAIITRHAFSSAPFKLAEFS 123
Query: 123 SVPVINGLSDFS-HPCQALADYMTIWEKKGT---IKGVKVVYVGDGNN--VAHSLMIAGT 176
P+IN S S HP QAL D +T+++ G+ +KG K+ ++GD N VA+S +
Sbjct: 124 QCPLINAGSGVSAHPTQALLDLLTLYQHFGSLENLKGKKIAFIGDVKNSRVANSNIKLLQ 183
Query: 177 KLGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIY-------- 228
+LG ++++ P P S + H+ +A+ AD++
Sbjct: 184 RLGLEIMLCAPSSMLPSV---------------SLKTTHNVEEAIAFADILMSLRTQTER 228
Query: 229 --TDVWASMGQEAEAEERRKIFRPFQVNKDLVK-HAK-PDYMFMHCLPAHRGEEVTDDVI 284
T ++AS+ A + + + +K HAK + + +H P HR ++ V+
Sbjct: 229 HNTPIFASLKDYGNA---------YCITQQRLKAHAKNKEVIILHPGPVHRDIDIESAVL 279
Query: 285 DSPNSVVWDEAENRLHAQKAVLALLL 310
+ S V ++ +N + + AVL LL
Sbjct: 280 EDERSKVLEQVKNGVAMRMAVLEFLL 305
>sp|P74163|PYRB_SYNY3 ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE TRANSCARBAMYLASE)
(ATCASE) >gi|7433608|pir||S75691 aspartate
carbamoyltransferase (EC 2.1.3.2) pyrB - Synechocystis
sp. (strain PCC 6803) >gi|1653337|dbj|BAA18252.1|
(D90912) aspartate carbamoyltransferase [Synechocystis
sp.]
Length = 331
Score = 92.1 bits (225), Expect = 8e-18
Identities = 89/328 (27%), Positives = 141/328 (42%), Gaps = 23/328 (7%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLK-IWQKIGKPHRLLEGKTLAMIFQKPSTR 59
MV S +L L D+ EE+ +L+TA + + K L+G+ + +F +PSTR
Sbjct: 3 MVASWTRNHILDLTDWRGEELDIVLQTATTFQQVLSGQTKKVPALQGQVVTNLFFEPSTR 62
Query: 60 TRVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLA 119
TR SFE+A L + + L +GETI DTA+ I + V
Sbjct: 63 TRSSFELAAKRLSADVMNFSPGTSSLTKGETILDTAKTYLAMGSDIFVIRHQQAGVPHFI 122
Query: 120 K------YASVPVIN-GLSDFSHPCQALADYMTIWEKKGT-------IKGVKVVYVGD-- 163
V V+N G HP Q L D TI + ++G K+ VGD
Sbjct: 123 ASQMDRLQTGVKVLNAGDGQHEHPSQGLLDLFTICSQFAPDNPAIQCLQGKKIAVVGDIL 182
Query: 164 GNNVAHSLMIAGTKLGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKD 223
+ VA S + + T GADV +A P P E + + A G A++
Sbjct: 183 HSRVARSNLWSLTTAGADVHLAGPPTLLPKE----FQQLTLAPGSGKLHCHWQLQPALEG 238
Query: 224 ADVIYTDVWASMGQEAEA-EERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDD 282
AD++ T A R+ F + D +K +P +H P +RG E++ +
Sbjct: 239 ADIVMTLRLQKERMTAHLLPSLREYHHYFGITHDRLKVCQPGVKVLHPGPVNRGVEISSE 298
Query: 283 VIDSPN-SVVWDEAENRLHAQKAVLALL 309
++D P+ S++ D+ + + + A+L LL
Sbjct: 299 LMDDPDISLIQDQVTSGVAIRMALLYLL 326
>pir||C33917 pyrimidine synthesis protein CAD - Chinese hamster (fragment)
Length = 156
Score = 91.7 bits (224), Expect = 1e-17
Identities = 54/154 (35%), Positives = 87/154 (56%), Gaps = 1/154 (0%)
Query: 4 SLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVS 63
SL G+ +L ++ +T +++ + A L++ + + +L+GK +A +F + STRT S
Sbjct: 3 SLVGQHILSVKQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSS 62
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS 123
F AMA LGG L + +++GE++AD+ + +S Y D ++ R VE AK+
Sbjct: 63 FAAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCR 122
Query: 124 VPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGV 156
PVIN G HP QAL D TI E+ GT+ G+
Sbjct: 123 RPVINAGDGVGEHPTQALLDIFTIREELGTVNGM 156
>sp|Q55338|PYRB_SULAC ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE TRANSCARBAMYLASE)
(ATCASE) >gi|1486468|emb|CAA68165.1| (X99872) aspartate
carbamoyltransferase [Sulfolobus acidocaldarius]
Length = 299
Score = 91.7 bits (224), Expect = 1e-17
Identities = 76/288 (26%), Positives = 140/288 (48%), Gaps = 21/288 (7%)
Query: 32 KIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAMAHLGGHAL-YLNAQDLQLRRGET 90
K + + ++L GKT+++ F +PSTRT +SF+ A+ +LGG + + + + +GE
Sbjct: 24 KYSKNLNDTRKILSGKTISIAFFEPSTRTYLSFQKAIINLGGDVIGFSGEESTSVAKGEN 83
Query: 91 IADTARVLSRYVDAIMARVYDHKDVEDLAKYAS----VPVIN-GLSDFSHPCQALADYMT 145
+ADT R+L+ Y D I+ R HK + +++AS +PVIN G HP QA+ D T
Sbjct: 84 LADTIRMLNNYSDGIVMR---HK-YDGASRFASEISDIPVINAGDGKHEHPTQAVIDIYT 139
Query: 146 IWEKKGTIKGVKVVYVGDGN--NVAHSLMIAGTKLGADVVVATPEGYEPDEKVIKWAEQN 203
I + TI G+ +GD +SL+ T+ +V Y ++++ ++
Sbjct: 140 INKHFNTIDGLVFALLGDLKYARTVNSLLRILTRFRPKLV------YLISPQLLRARKEI 193
Query: 204 AAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRKIFRPFQVNKDLVKHAKP 263
E + + +P + + + DV+Y + + E KI + V+ DL K
Sbjct: 194 LDELNYPVKEVENPFEVINEVDVLYV-TRIQKERFVDEMEYEKIKGSYIVSLDLANKMKK 252
Query: 264 DYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVLALLLG 311
D + +H LP R E+ V + + +++A + + ++L + G
Sbjct: 253 DSIILHPLP--RVNEIDRKVDKTTKAKYFEQASYGVPVRMSILTKIYG 298
>sp|P16964|OTCX_STRPY PROBABLE ORNITHINE CARBAMOYLTRANSFERASE (OTC)
Length = 108
Score = 88.2 bits (215), Expect = 1e-16
Identities = 46/108 (42%), Positives = 64/108 (58%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
M +GR L +D+T E+ +++ + LK +K G PH LEGK +A++F+K STRT
Sbjct: 1 MTQVFQGRSFLAEKDFTRAELEYLIDFSAHLKDLKKRGVPHHYLEGKNIALLFEKTSTRT 60
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMAR 108
R +F A LG H YL A D+QL + E+ DTA+VL R D I R
Sbjct: 61 RAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMFDGIEFR 108
>pir||PE0009 ornithine carbamoyltransferase homolog - Streptococcus pyogenes
(fragment) >gi|217042|dbj|BAA02940.1| (D13790) ORF3
[Streptococcus pyogenes]
Length = 107
Score = 87.8 bits (214), Expect = 2e-16
Identities = 45/105 (42%), Positives = 63/105 (59%)
Query: 1 MVVSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRT 60
M +GR L +D+T E+ +++ + LK +K G PH LEGK +A++F+K STRT
Sbjct: 1 MTQVFQGRSFLAEKDFTRAELEYLIDFSAHLKDLKKRGVPHHYLEGKNIALLFEKTSTRT 60
Query: 61 RVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAI 105
R +F A LG H YL A D+QL + E+ DTA+VL R D I
Sbjct: 61 RAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMFDGI 105
>sp|P05990|PYR1_DROME CAD PROTEIN (RUDIMENTARY PROTEIN) [INCLUDES: GLUTAMINE-DEPENDENT
CARBAMOYL-PHOSPHATE SYNTHASE ; ASPARTATE
CARBAMOYLTRANSFERASE ; DIHYDROOROTASE ]
>gi|2144531|pir||QZFF rudimentary protein - fruit fly
(Drosophila melanogaster)
Length = 2236
Score = 87.4 bits (213), Expect = 2e-16
Identities = 75/313 (23%), Positives = 138/313 (43%), Gaps = 14/313 (4%)
Query: 4 SLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVS 63
SL G+ +L + + + + I A++LK+ +P LL GK +A +F + STRT S
Sbjct: 1919 SLMGKHILAVDMFNKDHLNDIFNLAQLLKLRGTKDRPVALLPGKIMASVFYEVSTRTPCS 1978
Query: 64 FEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAK--Y 121
F AM LGG + ++ +++GET +R+ + + R H +A+ +
Sbjct: 1979 FAAAMLRLGGRVISMDNITSSVKKGETWRTASRLCPAMPTSWLLR---HPSPGAVARTTF 2035
Query: 122 ASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNN--VAHSLMIAGTKLG 179
+ + H QAL D T GT+ G+ + VGD N HSL T
Sbjct: 2036 SQSRLSMPACRREHSHQALLDIFTDPRVGGTVNGLTITMVGDLKNGRTVHSLARLLTLYN 2095
Query: 180 ADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEA 239
++ P + ++V+++ Q + D + D DV+Y +
Sbjct: 2096 VNLQYVAPNSLQMPDEVVQFVHQRGVKQ----LFARDLKNVLPDTDVLYM-TRIQRERFD 2150
Query: 240 EAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRL 299
E+ K + + + AK + +H LP R E++ ++ P + + +AE +
Sbjct: 2151 NVEDYEKCCGHLVLTPEHMMRAKKRSIVLHPLP--RLNEISREIDLDPRAAYFRQAEYGM 2208
Query: 300 HAQKAVLALLLGG 312
+ + A+LA+++GG
Sbjct: 2209 YIRMALLAMVVGG 2221
>emb|CAB93367.1| (AL357523) aspartate carbamoyltransferase [Streptomyces coelicolor
A3(2)]
Length = 326
Score = 86.2 bits (210), Expect = 5e-16
Identities = 91/321 (28%), Positives = 141/321 (43%), Gaps = 27/321 (8%)
Query: 8 RDLLCLQDYTPEEIWTILETAK-MLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEV 66
R L+ D T ++ IL+TA+ M ++ + K L G+T+ +F + STRTR+SFE
Sbjct: 3 RHLISAADLTRDDAVLILDTAEEMARVADRPIKKLPTLRGRTVVNLFFEDSTRTRISFEA 62
Query: 67 AMAHLGGHALYLNAQDLQLRRGETIADTARVLSRY-VDAIMARVYDHKDVEDLAK--YAS 123
A L + A+ + +GE++ DTA+ L VDA++ R LA +
Sbjct: 63 AEKRLSADVINFTAKGSSVSKGESLKDTAQTLEAMGVDAVVIRHSASGAPYRLATSGWID 122
Query: 124 VPVIN-GLSDFSHPCQALADYMTIWEK--------KGTIKGVKVVYVGD--GNNVAHSLM 172
V+N G HP QAL D T+ + + G ++ VGD + VA S +
Sbjct: 123 AAVVNAGDGTHQHPTQALLDAFTMRRRLVGRDAGLGKDLDGRRITLVGDILHSRVARSNV 182
Query: 173 IAGTKLGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDAD-VIYTDV 231
LGA+V + P P V W E+ +D + +D V+ V
Sbjct: 183 DLLHTLGAEVTLVAPPTLLP-VGVETW----------PCEVSYDLDSTLPKSDAVMLLRV 231
Query: 232 WASMGQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVV 291
A R+ R + ++ D + + MH P RG E+T +V DS V
Sbjct: 232 QRERMNAAFFPTEREYSRRYGLDGDRMAKMPDHAIVMHPGPMVRGMEITAEVADSDRCTV 291
Query: 292 WDEAENRLHAQKAVLALLLGG 312
++ N + + AVL LLLGG
Sbjct: 292 VEQVTNGVSIRMAVLYLLLGG 312
>gb|AAF72727.1| (AF264709) aspartate transcarbamoylase [Enterococcus faecalis]
Length = 308
Score = 83.5 bits (203), Expect = 3e-15
Identities = 87/317 (27%), Positives = 144/317 (44%), Gaps = 25/317 (7%)
Query: 3 VSLKGRDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRV 62
+SLK LL + T E+ ++ A K K R L F + STRT
Sbjct: 8 ISLK--HLLTAEALTDREVMGLIRRAGEFKQGAKWHPEERQYFATNL---FFENSTRTHK 62
Query: 63 SFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRY-VDAIMARVYDHKDVEDL--A 119
SFEVA LG + A +++GET+ DT +S VD + R ++L +
Sbjct: 63 SFEVAEKKLGLEVIEFEASRSSVQKGETLYDTVLTMSAIGVDVAVIRHGKENYYDELIQS 122
Query: 120 KYASVPVINGLSDFS--HPCQALADYMTIWEKKGTIKGVKVVYVGD--GNNVAHSLMIAG 175
K +ING D S HP Q L D MTI+E+ G +G+KV VGD + VA S M
Sbjct: 123 KTIQCSIING-GDGSGQHPTQCLLDLMTIYEEFGGFEGLKVAIVGDITHSRVAKSNMQLL 181
Query: 176 TKLGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASM 235
+LGA++ + PE +W + + + G + L + V+ V ++
Sbjct: 182 NRLGAEIYFSGPE---------EWYD-HQFDVYGQYVPLDEIVEKVDVMMLLRVQHERHD 231
Query: 236 GQEAEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEA 295
G+E+ ++E + + + + + + MH P +R E+ D++++S S + +
Sbjct: 232 GKESFSKEGYHL--EYGLTNERATRLQKHAIIMHPAPVNRDVELADELVESLQSRIVAQM 289
Query: 296 ENRLHAQKAVLALLLGG 312
N + + A+L +L G
Sbjct: 290 SNGVFMRMAILEAILHG 306
>gb|AAK40925.1| Aspartate carbamoyltransferase catalytic chain (ATCase) (pyrB)
[Sulfolobus solfataricus]
Length = 303
Score = 80.4 bits (195), Expect = 3e-14
Identities = 80/313 (25%), Positives = 142/313 (44%), Gaps = 27/313 (8%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
R ++ D T ++ + I E A +K+ L GK +++ F +PSTRT SF A
Sbjct: 4 RHVVSSLDLTRDDYFRIFELADKFYDVKKLN----YLSGKVVSLAFFEPSTRTAQSFHTA 59
Query: 68 MAHLGGHAL-YLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS--- 123
LG + + + + + +GE +ADT R+L+ Y + I+ R HK + A +AS
Sbjct: 60 AIKLGADVIGFASEESTSIAKGENLADTIRMLNNYSNCIVMR---HK-FDGAALFASEIS 115
Query: 124 -VPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGN--NVAHSLMIAGTKL- 178
+P+IN G HP QA+ D T+++ G I G +GD +SL+ A T+
Sbjct: 116 DIPIINAGDGKHEHPTQAVIDLYTVYKAFGEIDGRTFALLGDLKYARTVNSLLRALTRFK 175
Query: 179 GADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQE 238
V + +P + +++ E+ +P +++ DV+Y +
Sbjct: 176 PKKVFLISPSQLKVRREILDELNYPVIET-------ENPYDVIQEIDVLYV-TRIQKERF 227
Query: 239 AEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENR 298
+ E K+ + V+ LV K D + +H LP R E+ V + N+ + +A
Sbjct: 228 VDEVEYEKVKESYVVDLKLVNMMKKDGIILHPLP--RVTEIDRRVDKTVNAKYFYQASLA 285
Query: 299 LHAQKAVLALLLG 311
+ + A+ +LG
Sbjct: 286 VPVRMALFYEVLG 298
>sp|Q9UX08|PYRB_SULSO ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE TRANSCARBAMYLASE)
(ATCASE) >gi|6015859|emb|CAB57686.1| (Y18930) aspartate
carbamoyltransferase catalytic chain, (ATCASE)
[Sulfolobus solfataricus]
Length = 303
Score = 80.4 bits (195), Expect = 3e-14
Identities = 80/313 (25%), Positives = 142/313 (44%), Gaps = 27/313 (8%)
Query: 8 RDLLCLQDYTPEEIWTILETAKMLKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVA 67
R ++ D T ++ + I E A +K+ L GK +++ F +PSTRT SF A
Sbjct: 4 RHVVSSLDLTRDDYFRIFELADKFYDVKKLN----YLSGKVVSLAFFEPSTRTAQSFHTA 59
Query: 68 MAHLGGHAL-YLNAQDLQLRRGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYAS--- 123
LG + + + + + +GE +ADT R+L+ Y + I+ R HK + A +AS
Sbjct: 60 AIKLGADVIGFASEESTSIAKGENLADTIRMLNNYSNCIVMR---HK-FDGAALFASEIS 115
Query: 124 -VPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGN--NVAHSLMIAGTKL- 178
+P+IN G HP QA+ D T+++ G I G +GD +SL+ A T+
Sbjct: 116 DIPIINAGDGKHEHPTQAVIDLYTVYKAFGEIDGRTFALLGDLKYARTVNSLLRALTRFK 175
Query: 179 GADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQE 238
V + +P + +++ E+ +P +++ DV+Y +
Sbjct: 176 PKKVFLISPSQLKVRREILDELNYPVIET-------ENPYDVIQEIDVLYV-TRIQKERF 227
Query: 239 AEAEERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENR 298
+ E K+ + V+ LV K D + +H LP R E+ V + N+ + +A
Sbjct: 228 VDEVEYEKVKESYVVDLKLVNMMKKDGIILHPLP--RVTEIDRRVDKTVNAKYFYQASLA 285
Query: 299 LHAQKAVLALLLG 311
+ + A+ +LG
Sbjct: 286 VPVRMALFYEVLG 298
>pir||S47625 aspartate carbamoyltransferase (EC 2.1.3.2) - wheat (fragment)
>gi|688218|gb|AAB31820.1| aspartate carbamoyltransferase
{C-terminal} {EC 2.1.3.2} [Triticum aestivum=wheat,
avalon, seedlings, Peptide Partial, 233 aa]
Length = 233
Score = 78.0 bits (189), Expect = 1e-13
Identities = 67/233 (28%), Positives = 108/233 (45%), Gaps = 14/233 (6%)
Query: 87 RGETIADTARVLSRYVDAIMARVYDHKDVEDLAKYASVPVIN-GLSDFSHPCQALADYMT 145
+GET+ DT R + Y D I+ R ++ A A +PVIN G HP QAL D T
Sbjct: 2 KGETLEDTIRTVEGYSDIIVLRHFESGAARRAAATAEIPVINAGDGPGQHPTQALLDVYT 61
Query: 146 IWEKKGTIKGVKVVYVGD---GNNVAHSLMIAGTKLGADVVVATPEGYEPDEKVIKWAEQ 202
I + G + G+K+ VGD G V + + +P+ + + + ++
Sbjct: 62 IKREIGRLDGIKLGLVGDLANGRTVRSLAYLIAKYQNIKIYFVSPDVVKMKDDIKEYLTS 121
Query: 203 NAAESGGSFELLHDPVKAVKDADVIY-TDVWAS-MGQEAEAEERRKIFRPFQVNKDLVKH 260
E S +LL DVIY T + G+ + E + + V+K +++
Sbjct: 122 QGVEWEESSDLL----DVASRCDVIYQTRIQKERFGERIDHYEAAR--GKYIVDKKVLRC 175
Query: 261 AKPDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVLALLLGGV 313
A + MH LP R +E+T DV P + + +A+N L+ + A+L LLL G+
Sbjct: 176 AAKHAVIMHPLP--RLDEITVDVDSDPRAAYFRQAKNGLYIRMALLKLLLVGL 226
>sp|Q60252|PYRB_LACLE ASPARTATE CARBAMOYLTRANSFERASE (ASPARTATE TRANSCARBAMYLASE)
(ATCASE) >gi|1359907|emb|CAA59021.1| (X84262) aspartate
transcarbamylase [Lactobacillus leichmannii]
Length = 351
Score = 75.3 bits (182), Expect = 9e-13
Identities = 69/277 (24%), Positives = 126/277 (44%), Gaps = 20/277 (7%)
Query: 52 IFQKPSTRTRVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRY-VDAIMARVY 110
+F + STRT SFEVA LG + + + +GE + DT ++ ++ + R
Sbjct: 80 MFFENSTRTHTSFEVAERRLGLTVIPFDPSHSSVNKGENLYDTELTMASLGIELSVIRHP 139
Query: 111 DHKDVEDLAK-----YASVPVIN-GLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDG 164
++ ++ + + + ++N G HP Q++ D MTI+ + G G+K++ VGD
Sbjct: 140 ENAYYNEIIRPKEGQHLQMGLVNAGDGSGQHPSQSMLDMMTIYNEFGHFDGLKIMIVGDL 199
Query: 165 NN--VAHSLMIAGTKLGADVVVATPEGYEPDEKVIKWAEQNAAESGGSFELLHDPVKAVK 222
N VA S M LGA+V + PE + E+ K+ G + + D + +
Sbjct: 200 TNSRVARSNMEILNTLGAEVYFSGPEYWYNAEEFSKY--------GTYVKNIDDEIPELD 251
Query: 223 DADVIYTDVWASMGQEAEAE---ERRKIFRPFQVNKDLVKHAKPDYMFMHCLPAHRGEEV 279
++ G EA+ E + + + +N+ K D + MH P +RG E
Sbjct: 252 VLMLLRVQHERHNGAEAKTEQLFDAKDYNAAYGLNQRRYDMLKDDAIIMHPGPINRGVEW 311
Query: 280 TDDVIDSPNSVVWDEAENRLHAQKAVLALLLGGVKTG 316
D++++P S + N + + A++ +L G K G
Sbjct: 312 DGDLVEAPKSRYAVQMHNGVFVRMAMIEAVLRGRKLG 348
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.319 0.135 0.400
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 119401155
Number of Sequences: 2977
Number of extensions: 4839244
Number of successful extensions: 12238
Number of sequences better than 1.0e-10: 235
Number of HSP's better than 0.0 without gapping: 156
Number of HSP's successfully gapped in prelim test: 79
Number of HSP's that attempted gapping in prelim test: 11561
Number of HSP's gapped (non-prelim): 240
length of query: 317
length of database: 189,106,746
effective HSP length: 56
effective length of query: 261
effective length of database: 155,591,474
effective search space: 40609374714
effective search space used: 40609374714
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 165 (68.7 bits)