BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1523 (aspB-2) DE:aspartate aminotransferase (aspB-2)
(390 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||G75037 probable aromatic-amino-acid transaminase (EC 2.6.1.... 781 0.0
pir||E71125 probable aromatic-amino-acid transaminase (EC 2.6.1.... 713 0.0
pir||B75122 probable aromatic-amino-acid transaminase (EC 2.6.1.... 415 e-115
pir||E71009 probable aromatic-amino-acid transaminase (EC 2.6.1.... 414 e-115
sp|Q60317|AAT1_METJA PROBABLE ASPARTATE AMINOTRANSFERASE 1 (TRAN... 315 5e-85
sp|O67781|AAT_AQUAE ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) ... 311 7e-84
pir||G69119 probable aspartate transaminase (EC 2.6.1.1) MTH1894... 304 9e-82
gi|11499215 aspartate aminotransferase (aspB-3) [Archaeoglobus f... 294 1e-78
dbj|BAB07069.1| (AP001518) aspartate aminotransferase [Bacillus ... 293 3e-78
pir||C33496 hisC homolog - Bacillus subtilis 282 3e-75
pir||C69672 probable aspartate transaminase (EC 2.6.1.-) patA [s... 279 4e-74
sp|P16524|PATA_BACSU PUTATIVE AMINOTRANSFERASE A >gi|2632221|emb... 279 5e-74
pir||D72450 probable aspartate transaminase (EC 2.6.1.1) APE2248... 276 3e-73
gi|11499712 aspartate aminotransferase (aspB-2) [Archaeoglobus f... 272 4e-72
sp|Q56232|AAT_THETH ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) ... 271 1e-71
pdb|1BJW|A Chain A, Aspartate Aminotransferase From Thermus Ther... 268 6e-71
sp|O33822|AAT_THEAQ ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) ... 268 1e-70
dbj|BAB05414.1| (AP001512) aspartate aminotransferase [Bacillus ... 266 2e-70
sp|Q59228|AAT_BACST ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) ... 266 4e-70
emb|CAC11669.1| (AL445064) probable aspartate aminotransferase [... 265 7e-70
sp|P23034|AAT_BACSP ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) ... 264 1e-69
pir||D75496 aspartate transaminase (EC 2.6.1.1) DR0623 [similari... 263 3e-69
gb|AAD23617.1|AC007168_8 (AC007168) putative aspartate aminotran... 263 3e-69
sp|P53001|AAT1_BACSU ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A)... 263 3e-69
gb|AAB81842.1| (AF025665) aspartate aminotransferase [Thermus aq... 258 6e-68
gb|AAF06954.1|AF146529_1 (AF146529) aromatic amino acid aminotra... 254 1e-66
pir||D64385 aspartate transaminase (EC 2.6.1.1) - Methanococcus ... 252 6e-66
sp|Q58097|AAT2_METJA PROBABLE ASPARTATE AMINOTRANSFERASE 2 (TRAN... 252 6e-66
gb|AAK41178.1| Aspartate aminotransferase (aspB-2) [Sulfolobus s... 250 1e-65
sp|P14909|AAT_SULSO ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) ... 250 1e-65
pir||S45613 aspartate aminotransferase - Sulfolobus solfataricus 250 1e-65
sp|Q55128|AAT_SYNY3 ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) ... 250 2e-65
sp|Q02635|AATA_RHIME ASPARTATE AMINOTRANSFERASE A (TRANSAMINASE ... 246 4e-64
sp|Q9ZE56|AAT_RICPR ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) ... 245 6e-64
pir||B81347 aspartate transaminase (EC 2.6.1.1) Cj0762c [importe... 245 8e-64
sp|Q60013|AAT_STRVG ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) ... 242 7e-63
gi|11499943 aspartate aminotransferase (aspB-1) [Archaeoglobus f... 242 7e-63
gb|AAG19034.1| (AE005003) aspartate aminotransferase; AspB1 [Hal... 238 8e-62
gb|AAG19132.1| (AE005011) aspartate aminotransferase; AspB2 [Hal... 237 2e-61
emb|CAB77419.1| (AL160431) aspartate aminotransferase [Streptomy... 236 2e-61
pir||B72275 probable aspartate transaminase (EC 2.6.1.1) TM1255 ... 235 7e-61
sp|O86459|AAT_RHILP ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) ... 233 2e-60
gb|AAF12702.1|AF035157_1 (AF035157) aspartate aminotransferase [... 233 4e-60
pir||B70325 probable transaminase (EC 2.6.1.-) aspC4 [similarity... 229 4e-59
pir||F83024 aspartate transaminase PA4976 [imported] - Pseudomon... 228 7e-59
pir||D71003 probable transaminase (EC 2.6.1.-) PH1322 [similarit... 227 2e-58
pir||H71909 probable aspartate transaminase (EC 2.6.1.1) aspB [s... 224 1e-57
pir||H64603 probable aspartate transaminase (EC 2.6.1.1) P0672 [... 222 7e-57
pir||G70010 probable aspartate transaminase (EC 2.6.1.1) yugH [s... 221 9e-57
gb|AAF65616.1|AF163769_1 (AF163769) alanine aminotransferase [Py... 220 2e-56
pir||A75128 probable transaminase (EC 2.6.1.-) aspB-like2 PAB181... 219 3e-56
sp|Q06191|AATB_RHIME ASPARTATE AMINOTRANSFERASE B (TRANSAMINASE ... 219 6e-56
pir||E70338 probable aspartate transaminase (EC 2.6.1.1) aspC3 [... 217 2e-55
sp|P39643|AAT2_BACSU PROBABLE ASPARTATE AMINOTRANSFERASE (TRANSA... 216 3e-55
gi|11498021 aspartate aminotransferase (aspB-4) [Archaeoglobus f... 215 7e-55
gb|AAG00592.1| (AF289216) alanine aminotransferase [Thermococcus... 213 3e-54
dbj|BAB04779.1| (AP001510) aspartate aminotransferase [Bacillus ... 204 1e-51
emb|CAC11898.1| (AL445065) aspartate transaminase related protei... 198 1e-49
pir||F69863 probable transaminase (EC 2.6.1.-) ykrV [similarity]... 198 1e-49
pir||T36548 probable transaminase (EC 2.6.1.-) SCH10.36 [similar... 189 6e-47
gb|AAD56921.1|AF180145_13 (AF180145) aspartate aminotransferase ... 188 1e-46
gb|AAF07797.1|AC010704_22 (AC010704) putative aminotransferase; ... 187 2e-46
pir||D70479 probable transaminase (EC 2.6.1.-) aspC2 [similarity... 186 3e-46
pir||S76353 probable aspartate transaminase (EC 2.6.1.1) aspC sl... 186 4e-46
pir||E83056 probable aminotransferase PA4715 [imported] - Pseudo... 185 5e-46
sp|P77434|YFDZ_ECOLI HYPOTHETICAL AMINOTRANSFERASE YFDZ >gi|7447... 180 2e-44
pir||T35706 probable aspartate transaminase (EC 2.6.1.1) SC7H1.1... 179 5e-44
pir||F81432 probable transaminase (EC 2.6.1.-) Cj0150c [similari... 178 9e-44
emb|CAB45026.1| (AL078635) putative aminotransferase [Amycolatop... 178 1e-43
dbj|BAB04655.1| (AP001510) aspartate aminotransferase [Bacillus ... 178 1e-43
pir||D83057 probable aminotransferase PA4722 [imported] - Pseudo... 175 6e-43
emb|CAC03612.1| (AJ272538) putative aspartate amino transferase ... 175 8e-43
gb|AAG19511.1| (AE005042) aspartate aminotransferase; AspC2 [Hal... 175 1e-42
pir||A83171 probable aminotransferase PA3798 [imported] - Pseudo... 174 1e-42
pir||B70815 probable transaminase (EC 2.6.1.-) Rv0858c [similari... 173 2e-42
pir||G72655 aspartate transaminase (EC 2.6.1.1) APE0674 [similar... 173 2e-42
sp|P77806|YBDL_ECOLI HYPOTHETICAL AMINOTRANSFERASE YBDL >gi|7447... 171 1e-41
sp|O87320|AATC_RHIME PUTATIVE AMINOTRANSFERASE AATC 171 2e-41
emb|CAB44334.1| (Y17462) cysteine conjugate beta-lyase [Fugu rub... 169 4e-41
pir||T37220 probable transaminase (EC 2.6.1.-) SC2H4.04c [simila... 165 9e-40
gi|10954795 aatA gene in Rhizobium leguminosarum homolog~hypothe... 161 2e-38
sp|O14209|YDT4_SCHPO HYPOTHETICAL AMINOTRANSFERASE C6B12.04C >gi... 159 5e-38
sp|Q58786|YD91_METJA PUTATIVE AMINOTRANSFERASE MT1391 >gi|212783... 158 9e-38
sp|P77727|YFBQ_ECOLI PROBABLE AMINOTRANSFERASE YFBQ >gi|7447846|... 156 3e-37
pir||C70605 probable aspartate transaminase (EC 2.6.1.1) aspB [s... 156 3e-37
pir||D72220 probable aspartate transaminase (EC 2.6.1.1) TM1698 ... 155 6e-37
dbj|BAB05914.1| (AP001514) aspartate aminotransferase [Bacillus ... 155 1e-36
pir||B83293 probable aminotransferase PA2828 [imported] - Pseudo... 152 5e-36
pir||S48737 kynurenine aminotransferase - rat >gi|688258|gb|AAB3... 152 7e-36
gi|4757928 cytoplasmic cysteine conjugate-beta lyase; glutamine ... 152 7e-36
gb|AAF06837.1|AF100154_1 (AF100154) kynurenine aminotransferase/... 152 7e-36
pir||S75949 probable aspartate transaminase (EC 2.6.1.1) aspC sl... 152 9e-36
pir||H69826 aspartate aminotransferase homolog yhdR - Bacillus s... 152 9e-36
pir||I57944 cysteine conjugate beta-lyase - rat >gi|300516|gb|AA... 150 3e-35
pir||S66270 kynurenine--oxoglutarate transaminase (EC 2.6.1.7) /... 150 3e-35
pir||S74724 aspartate transaminase (EC 2.6.1.1) - Synechocystis ... 149 6e-35
pir||H82131 probable aspartate aminotransferase VC1977 [imported... 149 6e-35
dbj|BAA75925.1| (AB012002) aspartate aminotransferase [Pyrococcu... 148 1e-34
sp|P71348|YFBQ_HAEIN PROBABLE AMINOTRANSFERASE HI0286 >gi|157325... 147 2e-34
pir||T23861 kynurenine--oxoglutarate transaminase (EC 2.6.1.7) /... 147 2e-34
emb|CAA07075.1| (AJ006517) putative aminotransferase [Streptomyc... 147 2e-34
pir||G81863 probable aminotransferase (EC 2.6.1.-) NMA1684 [impo... 146 3e-34
gi|6322401 Yjl060wp [Saccharomyces cerevisiae] >gi|1176356|sp|P4... 146 3e-34
pir||G81078 aminotransferase, class I NMB1473 [imported] - Neiss... 145 7e-34
pir||C82564 aminotransferase XF2396 [imported] - Xylella fastidi... 144 1e-33
pir||E69168 probable transaminase (EC 2.6.1.-) MTH52 [similarity... 143 4e-33
pir||T21518 kynurenine--oxoglutarate transaminase (EC 2.6.1.7) /... 142 6e-33
sp|O33267|AAT_MYCTU PROBABLE ASPARTATE AMINOTRANSFERASE (TRANSAM... 141 1e-32
pir||A75490 probable transaminase (EC 2.6.1.-) DR0671 [similarit... 141 1e-32
gb|AAF54707.1| (AE003693) CG6950 gene product [alt 3] [Drosophil... 141 1e-32
emb|CAC04464.1| (AL391572) conserved hypothetical protein [Neuro... 138 8e-32
pir||E69093 aspartate aminotransferase related protein - Methano... 138 1e-31
pir||B36886 probable transaminase (EC 2.6.1.-) - Streptococcus s... 138 1e-31
dbj|BAB07032.1| (AP001518) aminotransferase [Bacillus halodurans] 137 2e-31
gb|AAF21128.1|L78665_2 (L78665) aspartate aminotransferase [Meth... 135 1e-30
pir||G75294 probable transaminase (EC 2.6.1.-) DR2268 [similarit... 134 2e-30
pir||T22087 hypothetical protein F42D1.2 - Caenorhabditis elegan... 134 2e-30
gb|AAF27693.1|AC018848_10 (AC018848) putative aspartate aminotra... 133 4e-30
pir||D81146 aminotransferase, class I NMB0894 [imported] - Neiss... 129 7e-29
pir||E81877 probable aminotransferase NMA1113 [imported] - Neiss... 128 1e-28
gb|AAK40460.1| Aspartate aminotransferase (aspB-1) [Sulfolobus s... 127 2e-28
pir||S75385 probable valine--pyruvate transaminase (EC 2.6.1.66)... 127 2e-28
gb|AAA42203.1| (M18340) tyrosine aminotransferase (EC 2.6.1.5) [... 126 4e-28
gi|6981630 tyrosine aminotransferase [Rattus norvegicus] >gi|114... 126 5e-28
sp|Q58365|HIS8_METJA PROBABLE HISTIDINOL-PHOSPHATE AMINOTRANSFER... 126 5e-28
emb|CAA09309.1| (AJ010709) tyrosine aminotransferase [Rattus nor... 126 5e-28
pir||S76639 probable transaminase (EC 2.6.1.-) sll0480 [similari... 125 1e-27
gb|AAG37063.1|AF301900_1 (AF301900) ROOTY/SUPERROOT1 [Arabidopsi... 125 1e-27
gb|AAG37062.1|AF301899_1 (AF301899) ROOTY/SUPERROOT1 [Arabidopsi... 124 1e-27
pir||C71917 probable transaminase (EC 2.6.1.-) jhp0568 [similari... 123 3e-27
gi|4507369 tyrosine aminotransferase; Tyrosine aminotransferase,... 122 9e-27
gi|11432387 tyrosine aminotransferase [Homo sapiens] 122 9e-27
gb|AAD21706.1| (AC007048) putative tyrosine aminotransferase [Ar... 120 4e-26
pir||E71243 probable valine--pyruvate transaminase (EC 2.6.1.66)... 119 5e-26
pir||H64597 probable transaminase (EC 2.6.1.-) HP0624 [similarit... 117 2e-25
pir||F83189 probable aminotransferase PA3659 [imported] - Pseudo... 117 2e-25
gb|AAD15433.1| (AC006218) putative aspartate aminotransferase [A... 117 2e-25
gb|AAC67987.2| (AE001312) Aspartate Aminotransferase [Chlamydia ... 117 2e-25
pir||D71520 probable transaminase (EC 2.6.1.-) aspC [similarity]... 117 2e-25
pir||E75208 probable valine--pyruvate transaminase (EC 2.6.1.66)... 116 3e-25
sp|Q08432|PATB_BACSU PUTATIVE AMINOTRANSFERASE B >gi|421526|pir|... 115 7e-25
gb|AAD45375.1|AF163863_1 (AF163863) tyrosine aminotransferase [M... 115 7e-25
gb|AAF73587.1| (AE002334) aminotransferase, class I [Chlamydia m... 113 4e-24
sp|Q50672|YM94_MYCTU PUTATIVE AMINOTRANSFERASE RV2294 >gi|744782... 113 5e-24
pir||H72293 probable valine--pyruvate transaminase (EC 2.6.1.66)... 111 1e-23
emb|CAC12318.1| (AL445066) aspartate aminotransferase related pr... 111 1e-23
dbj|BAA86884.1| (AB027131) multiple substrate aminotransferase (... 111 1e-23
gb|AAF86990.1|AF282249_9 (AF282249) ArcT [Lactococcus lactis sub... 109 4e-23
gb|AAF48363.1| (AE003495) CG1461 gene product [Drosophila melano... 109 5e-23
gi|11499606 histidinol-phosphate aminotransferase (hisC-2) [Arch... 108 9e-23
pir||T04985 probable transaminase (EC 2.6.1.-) T16L1.170 [simila... 108 9e-23
pir||F72072 probable transaminase (EC 2.6.1.-) aspC [similarity]... 108 9e-23
gb|AAK40904.1| Histidinol-phosphate aminotransferase (hisC) [Sul... 107 3e-22
sp|O33770|HIS8_SULSO HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMID... 107 3e-22
pir||F72772 probable valine--pyruvate transaminase (EC 2.6.1.66)... 104 2e-21
pir||T46744 probable transaminase arcT [imported] - Lactobacillu... 104 2e-21
pir||D70849 probable aminotransferase - Mycobacterium tuberculos... 103 3e-21
gb|AAA85439.1| (U30249) hemolysin [Treponema denticola] 100 3e-20
pdb|1C7N|A Chain A, Crystal Structure Of Cystalysin From Trepone... 97 3e-19
pir||F64484 probable transaminase (EC 2.6.1.-) MJ1479 [similarit... 97 4e-19
gb|AAG10013.1| (AF279917) aspartate aminotransferase [Azospirill... 97 4e-19
dbj|BAB04151.1| (AP001508) transcriptional regulator (GntR famil... 96 9e-19
emb|CAA63240.1| (X92496) Aat-like protein [Azospirillum brasilense] 95 2e-18
pir||T36254 probable valine--pyruvate transaminase (EC 2.6.1.66)... 92 8e-18
dbj|BAB04846.1| (AP001511) aminotransferase [Bacillus halodurans] 92 8e-18
dbj|BAB05384.1| (AP001512) histidinol-phosphate aminotransferase... 92 1e-17
gb|AAC61900.1| (AF031938) hypothetical protein [Sinorhizobium me... 92 1e-17
pir||H83438 probable aminotransferase PA1654 [imported] - Pseudo... 91 2e-17
pir||B75395 aminotransferase, class I - Deinococcus radiodurans ... 90 3e-17
pir||B69780 transcription regulator GntR family homolog ydfD - B... 90 5e-17
pir||T14609 alanine transaminase homolog - Trypanosoma cruzi >gi... 90 5e-17
gb|AAF50113.1| (AE003546) CG6321 gene product [Drosophila melano... 89 9e-17
gi|6754408 kynurenine aminotransferase II [Mus musculus] >gi|510... 89 1e-16
gb|AAK43337.1| Aspartate aminotransferase (aspB-4) [Sulfolobus s... 87 3e-16
emb|CAA08874.1| (AJ009834) DapC [Bordetella pertussis] 87 4e-16
sp|Q10334|ALAT_SCHPO PUTATIVE ALANINE AMINOTRANSFERASE (GLUTAMIC... 85 1e-15
emb|CAC14933.1| (AL449216) putative transferase [Streptomyces co... 85 2e-15
sp|Q00379|1A12_CUCPE 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE ... 80 3e-14
gb|AAF42764.1|AF128839_8 (AF128839) unknown [Salmonella enteriti... 80 3e-14
dbj|BAA94600.1| (AB033503) 1-aminocyclopropane-1-carboxylate syn... 80 3e-14
pir||A41141 1-aminocyclopropane-1-carboxylate synthase (EC 4.4.1... 80 6e-14
pir||E70478 histidinol-phosphate aminotransferase - Aquifex aeol... 79 7e-14
sp|P23279|1A11_CUCPE 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE ... 79 1e-13
emb|CAB61674.1| (AL133213) putative GntR-family regulatory prot... 79 1e-13
gb|AAC83146.1| (AF057562) 1-aminocyclopropane-1-carboxylate synt... 78 1e-13
emb|CAC12206.1| (AL445066) aspartate aminotransferase related pr... 78 1e-13
sp|P23599|1A11_CUCMA 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE ... 78 2e-13
pir||E83392 probable transcription regulator PA2032 [imported] -... 78 2e-13
gb|AAA33112.1| (M61195) 1-aminocyclopropane-1-carboxylate syntha... 77 3e-13
pir||G75446 probable valine--pyruvate transaminase (EC 2.6.1.66)... 77 3e-13
gb|AAC18908.1| (M89931) beta C-S lyase [Corynebacterium glutamicum] 76 5e-13
pir||T06252 1-aminocyclopropane-1-carboxylate synthase (EC 4.4.1... 76 6e-13
sp|Q00257|1A12_CUCMA 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE ... 76 8e-13
pir||T09658 1-aminocyclopropane-1-carboxylate synthase (EC 4.4.1... 76 8e-13
dbj|BAA93712.1| (AB032935) 1-aminocyclopropane-1-carboxylate syn... 76 8e-13
emb|CAB56665.1| (AL121596) aminotransferase [Streptomyces coelic... 75 1e-12
emb|CAB01401.1| (Z77854) 1-aminocyclopropane-carboxylate synthas... 75 2e-12
dbj|BAA33374.1| (AB006803) ACC synthase [Cucumis sativus] >gi|74... 73 4e-12
pir||T10889 1-aminocyclopropane-1-carboxylate synthase (EC 4.4.1... 73 6e-12
pir||E75378 probable valine--pyruvate transaminase (EC 2.6.1.66)... 73 6e-12
dbj|BAA33376.1| (AB006805) ACC synthase [Cucumis sativus] 73 7e-12
pir||E83130 conserved hypothetical protein PA4132 [imported] - P... 73 7e-12
gb|AAC63850.1| (U73786) ACC synthase [Arabidopsis thaliana] 71 3e-11
gb|AAA78273.1| (U34986) 1-aminocyclopropane-1-carboxylic acid sy... 70 4e-11
pir||T13019 1-aminocyclopropane-1-carboxylate synthase (EC 4.4.1... 70 4e-11
pir||G82405 transcription regulator GntR family VCA0871 [importe... 70 4e-11
pir||H83282 probable transcriptional regulator PA2897 [imported]... 70 4e-11
gb|AAF22112.1|AF119414_1 (AF119414) 1-aminocyclopropane-1-carbox... 70 5e-11
pir||T47022 hypothetical protein [imported] - Yersinia pestis >g... 69 6e-11
pir||T06253 1-aminocyclopropane-1-carboxylate synthase (EC 4.4.1... 69 8e-11
>pir||G75037 probable aromatic-amino-acid transaminase (EC 2.6.1.57) PAB1523
[similarity] - Pyrococcus abyssi (strain Orsay)
>gi|5458709|emb|CAB50196.1| (AJ248287) aspartate
aminotransferase (aspB-2) [Pyrococcus abyssi]
Length = 390
Score = 781 bits (1994), Expect = 0.0
Identities = 390/390 (100%), Positives = 390/390 (100%)
Query: 1 MRQKRKYFIAERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDE 60
MRQKRKYFIAERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDE
Sbjct: 1 MRQKRKYFIAERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDE 60
Query: 61 GWTHYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVL 120
GWTHYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVL
Sbjct: 61 GWTHYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVL 120
Query: 121 IPDPAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGA 180
IPDPAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGA
Sbjct: 121 IPDPAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGA 180
Query: 181 TLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAM 240
TLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAM
Sbjct: 181 TLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAM 240
Query: 241 TGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNER 300
TGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNER
Sbjct: 241 TGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNER 300
Query: 301 RKLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKM 360
RKLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKM
Sbjct: 301 RKLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKM 360
Query: 361 GEGYVRISYATSREKLMEAMDRMEKALSEL 390
GEGYVRISYATSREKLMEAMDRMEKALSEL
Sbjct: 361 GEGYVRISYATSREKLMEAMDRMEKALSEL 390
>pir||E71125 probable aromatic-amino-acid transaminase (EC 2.6.1.57) PH0771
[similarity] - Pyrococcus horikoshii
>gi|3257180|dbj|BAA29863.1| (AP000003) 391aa long
hypothetical aspartate aminotransferase [Pyrococcus
horikoshii]
Length = 391
Score = 713 bits (1820), Expect = 0.0
Identities = 342/387 (88%), Positives = 375/387 (96%)
Query: 1 MRQKRKYFIAERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDE 60
MR+KRKYFIAERV+LIKRSKIRELFERASKME+VISLGIGEPDFDTPKNIKEA KRALDE
Sbjct: 1 MREKRKYFIAERVLLIKRSKIRELFERASKMEDVISLGIGEPDFDTPKNIKEAAKRALDE 60
Query: 61 GWTHYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVL 120
GWTHYTPNAGI +LREAVVEYYKKFY +DI+VENVIITAGAYEGTYLAFESLLE GDEV+
Sbjct: 61 GWTHYTPNAGIPELREAVVEYYKKFYGIDIEVENVIITAGAYEGTYLAFESLLERGDEVI 120
Query: 121 IPDPAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGA 180
IPDPAFVSY EDAK+AEAKPVRIPLREENNF+PDP+ELLE ++K TRMIVINYPNNPTGA
Sbjct: 121 IPDPAFVSYAEDAKVAEAKPVRIPLREENNFLPDPNELLEKISKNTRMIVINYPNNPTGA 180
Query: 181 TLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAM 240
TLDKE+AK IADIA+DYNIYILSDEPYEHFIY+DAKHYPM+KFAPENTILANSFSKTFAM
Sbjct: 181 TLDKELAKTIADIAEDYNIYILSDEPYEHFIYEDAKHYPMIKFAPENTILANSFSKTFAM 240
Query: 241 TGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNER 300
TGWRLGFVVAPS++IKEM KLHAY+IGNVASF+Q+AG+EALRSEESWKAV+EM+KEYNER
Sbjct: 241 TGWRLGFVVAPSQVIKEMTKLHAYVIGNVASFVQIAGIEALRSEESWKAVEEMKKEYNER 300
Query: 301 RKLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKM 360
RK+V+KRLK MPGI+VKEPKGAFYVFP+I TGMSSEKFSEWLLEKARVVVIPGTAFG+M
Sbjct: 301 RKIVVKRLKNMPGIKVKEPKGAFYVFPNISGTGMSSEKFSEWLLEKARVVVIPGTAFGRM 360
Query: 361 GEGYVRISYATSREKLMEAMDRMEKAL 387
GEGYVRISYATS+EKL+EAM+R+EKAL
Sbjct: 361 GEGYVRISYATSKEKLIEAMNRIEKAL 387
>pir||B75122 probable aromatic-amino-acid transaminase (EC 2.6.1.57) PAB0525
[similarity] - Pyrococcus abyssi (strain Orsay)
>gi|5458202|emb|CAB49691.1| (AJ248285) aspartate
aminotransferase (aspC) [Pyrococcus abyssi]
Length = 389
Score = 415 bits (1055), Expect = e-115
Identities = 213/384 (55%), Positives = 278/384 (71%), Gaps = 4/384 (1%)
Query: 9 IAERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPN 68
+++R+ L+ S+IR+LF+ A+ M++VISLGIGEPDFDTP++IKE K ALD G THY PN
Sbjct: 3 MSDRLDLVNPSEIRKLFDIAAGMKDVISLGIGEPDFDTPQHIKEYAKEALDMGLTHYGPN 62
Query: 69 AGIQQLREAVVEYYKKFYDVDIDV-ENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
G+ +LREA+ E KK +++ D + +++ GA + + + L+ G+EVLIP PAFV
Sbjct: 63 IGLPELREAIAEKLKKQNNIEADPNKEIMVLVGANQAFLMGLSAFLKDGEEVLIPTPAFV 122
Query: 128 SYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVA 187
SY LA KPV +P EEN F + DEL + VT+KT+ ++IN P NPTG+ L K+
Sbjct: 123 SYAPAVILAGGKPVEVPTYEENEFRLNVDELKKYVTEKTKALIINSPCNPTGSVLKKKDL 182
Query: 188 KAIADIAQDYNIYILSDEPYEHFIYDDAKHYPM--LKFAPENTILANSFSKTFAMTGWRL 245
+ IAD A ++++ ++SDE YEHFIYDD KHY + L E TI N FSKTFAMTGWRL
Sbjct: 183 EEIADFAVEHDLIVISDEVYEHFIYDDVKHYSIASLDGMFERTITVNGFSKTFAMTGWRL 242
Query: 246 GFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVL 305
GFV APS II++M+K Y +FIQ A +ALR E SWKAV+EMRKEY+ RRKLV
Sbjct: 243 GFVAAPSWIIEKMVKFQMYNATCPVTFIQYAAAKALRDERSWKAVEEMRKEYDRRRKLVW 302
Query: 306 KRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYV 365
KRL EM G+ +PKGAFY+FP IKDTG++S++FSE +L +A+V V+PG+AFGK GEGYV
Sbjct: 303 KRLNEM-GLPTVKPKGAFYIFPRIKDTGLTSKEFSELMLMEAKVAVVPGSAFGKAGEGYV 361
Query: 366 RISYATSREKLMEAMDRMEKALSE 389
RISYAT+ EKL EAMDRMEK L E
Sbjct: 362 RISYATAYEKLEEAMDRMEKVLRE 385
>pir||E71009 probable aromatic-amino-acid transaminase (EC 2.6.1.57) PH1371
[similarity] - Pyrococcus horikoshii
>gi|3257794|dbj|BAA30477.1| (AP000006) 389aa long
hypothetical aspartate aminotransferase [Pyrococcus
horikoshii]
Length = 389
Score = 414 bits (1053), Expect = e-115
Identities = 212/384 (55%), Positives = 277/384 (71%), Gaps = 4/384 (1%)
Query: 9 IAERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPN 68
+++R+ L+ S+IR+LF+ A+ M++VISLGIGEPDFDTP++IKE K ALD+G THY PN
Sbjct: 3 LSDRLELVSASEIRKLFDIAAGMKDVISLGIGEPDFDTPQHIKEYAKEALDKGLTHYGPN 62
Query: 69 AGIQQLREAVVEYYKKFYDVDIDVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
G+ +LREA+ E KK ++ D + +++ GA + + + L+ G+EVLIP PAFV
Sbjct: 63 IGLLELREAIAEKLKKQNGIEADPKTEIMVLLGANQAFLMGLSAFLKDGEEVLIPTPAFV 122
Query: 128 SYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVA 187
SY LA KPV +P EE+ F + DEL + VT KTR ++IN P NPTGA L K+
Sbjct: 123 SYAPAVILAGGKPVEVPTYEEDEFRLNVDELKKYVTDKTRALIINSPCNPTGAVLTKKDL 182
Query: 188 KAIADIAQDYNIYILSDEPYEHFIYDDAKHYPM--LKFAPENTILANSFSKTFAMTGWRL 245
+ IAD ++++ ++SDE YEHFIYDDA+HY + L E TI N FSKTFAMTGWRL
Sbjct: 183 EEIADFVVEHDLIVISDEVYEHFIYDDARHYSIASLDGMFERTITVNGFSKTFAMTGWRL 242
Query: 246 GFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVL 305
GFV APS II+ M+K Y +FIQ A +AL+ E SWKAV+EMRKEY+ RRKLV
Sbjct: 243 GFVAAPSWIIERMVKFQMYNATCPVTFIQYAAAKALKDERSWKAVEEMRKEYDRRRKLVW 302
Query: 306 KRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYV 365
KRL EM G+ +PKGAFY+FP I+DTG++S+KFSE +L++ARV V+PG+AFGK GEGYV
Sbjct: 303 KRLNEM-GLPTVKPKGAFYIFPRIRDTGLTSKKFSELMLKEARVAVVPGSAFGKAGEGYV 361
Query: 366 RISYATSREKLMEAMDRMEKALSE 389
RISYAT+ EKL EAMDRME+ L E
Sbjct: 362 RISYATAYEKLEEAMDRMERVLKE 385
>sp|Q60317|AAT1_METJA PROBABLE ASPARTATE AMINOTRANSFERASE 1 (TRANSAMINASE A) (ASPAT)
>gi|2127774|pir||A64300 aspartate transaminase (EC
2.6.1.1) - Methanococcus jannaschii
>gi|1592252|gb|AAB97984.1| (U67459) aspartate
aminotransferase (aspB1) [Methanococcus jannaschii]
Length = 375
Score = 315 bits (799), Expect = 5e-85
Identities = 174/378 (46%), Positives = 244/378 (64%), Gaps = 18/378 (4%)
Query: 9 IAERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPN 68
I+ R IK S IRE+F A+ + I+LGIGEPDFDTPK+I EA KRALDEG THY+PN
Sbjct: 2 ISSRCKNIKPSAIREIFNLATS--DCINLGIGEPDFDTPKHIIEAAKRALDEGKTHYSPN 59
Query: 69 AGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVS 128
GI +LRE + K Y++D+D +N+I+T GA E L+ +L++ GDEVLIP+P+FVS
Sbjct: 60 NGIPELREEISNKLKDDYNLDVDKDNIIVTCGASEALMLSIMTLIDRGDEVLIPNPSFVS 119
Query: 129 YVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAK 188
Y + AE K I L E NF D +++ E +TKKT++I+ N P+NPTG DKE K
Sbjct: 120 YFSLTEFAEGKIKNIDLDE--NFNIDLEKVKESITKKTKLIIFNSPSNPTGKVYDKETIK 177
Query: 189 AIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFV 248
+A+IA+DYN+ I+SDE Y+ IY D KHY ++F + IL N FSKT+AMTGWR+G++
Sbjct: 178 GLAEIAEDYNLIIVSDEVYDKIIY-DKKHYSPMQFT-DRCILINGFSKTYAMTGWRIGYL 235
Query: 249 VAPSEIIKE------MIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRK 302
E+ KE MIK+H Y +F Q + ALR S K V++M +E+ RR
Sbjct: 236 AVSDELNKELDLINNMIKIHQYSFACATTFAQYGALAALRG--SQKCVEDMVREFKMRRD 293
Query: 303 LVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGE 362
L+ LK++ +V +P GAFY+FP + + G E ++ L+E +V+ +PG AFG+ G
Sbjct: 294 LIYNGLKDI--FKVNKPDGAFYIFPDVSEYGDGVE-VAKKLIEN-KVLCVPGVAFGENGA 349
Query: 363 GYVRISYATSREKLMEAM 380
Y+R SYAT E + +A+
Sbjct: 350 NYIRFSYATKYEDIEKAL 367
>sp|O67781|AAT_AQUAE ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|7447804|pir||A70469 aspartate transaminase (EC
2.6.1.1) aspC1 [similarity] - Aquifex aeolicus
>gi|2984217|gb|AAC07746.1| (AE000766) aspartate
aminotransferase [Aquifex aeolicus]
Length = 394
Score = 311 bits (789), Expect = 7e-84
Identities = 165/392 (42%), Positives = 244/392 (62%), Gaps = 12/392 (3%)
Query: 9 IAERVILIKRSKIRELFERASKME----NVISLGIGEPDFDTPKNIKEACKRALDEGWTH 64
+A RV +K S + +A ++ +VI G GEPDFDTP IKEAC RAL EG T
Sbjct: 5 LASRVSHLKPSPTLTITAKAKELRAKGVDVIGFGAGEPDFDTPDFIKEACIRALREGKTK 64
Query: 65 YTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDP 124
Y P+AGI +LREA+ E K V+ ++++AGA +L F ++L+ GDEVL+P P
Sbjct: 65 YAPSAGIPELREAIAEKLLKENKVEYKPSEIVVSAGAKMVLFLIFMAILDEGDEVLLPSP 124
Query: 125 AFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDK 184
+V+Y E + PV +PL++E F +++ E VT++T+ IVIN PNNPTGA ++
Sbjct: 125 YWVTYPEQIRFFGGVPVEVPLKKEKGFQLSLEDVKEKVTERTKAIVINSPNNPTGAVYEE 184
Query: 185 EVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPE---NTILANSFSKTFAMT 241
E K IA+ + I+I+SDE YE+F+Y DAK F+ E T N+FSK+++MT
Sbjct: 185 EELKKIAEFCVERGIFIISDECYEYFVYGDAKFVSPASFSDEVKNITFTVNAFSKSYSMT 244
Query: 242 GWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERR 301
GWR+G+V P E K + L++ + NV +F Q +EAL++ +S V EMR + RR
Sbjct: 245 GWRIGYVACPEEYAKVIASLNSQSVSNVTTFAQYGALEALKNPKSKDFVNEMRNAFERRR 304
Query: 302 KLVLKRLKEMPGIRVKEPKGAFYVFPSIK---DTGMSSEKFSEWLLEKARVVVIPGTAFG 358
++ L ++PG+ V +P+GAFY+FP + K SE+LLEKA+V V+PG+AFG
Sbjct: 305 DTAVEELSKIPGMDVVKPEGAFYIFPDFSAYAEKLGGDVKLSEFLLEKAKVAVVPGSAFG 364
Query: 359 KMGEGYVRISYATSREKLMEAMDRMEKALSEL 390
G++R+SYA S E+L+E + R++KAL E+
Sbjct: 365 --APGFLRLSYALSEERLVEGIRRIKKALEEI 394
>pir||G69119 probable aspartate transaminase (EC 2.6.1.1) MTH1894 [similarity] -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2623027|gb|AAB86354.1| (AE000941) aspartate
aminotransferase homolog [Methanobacterium
thermoautotrophicum]
Length = 374
Score = 304 bits (771), Expect = 9e-82
Identities = 164/375 (43%), Positives = 245/375 (64%), Gaps = 12/375 (3%)
Query: 10 AERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNA 69
A RV I+ S+IR++FE A E+ I+LGIGEPDF P +++EA K A+DEG THYT N
Sbjct: 7 ASRVKDIQLSEIRKIFEVAD--EDTINLGIGEPDFSVPDHVREAVKDAVDEGLTHYTSNM 64
Query: 70 GIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSY 129
G+++LREA+ + K V + E++I+T GA E ++ ++LL+ GD LIPDP F+SY
Sbjct: 65 GMEELREAIADKLKSENRVHAEPESIIVTVGASEAIFMCTQALLDIGDHALIPDPGFLSY 124
Query: 130 VEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKA 189
+L+ A + +PL + F P+ + L+T+ TR+I++N P+NPTG+ + K+ K
Sbjct: 125 DACVRLSGAVSIPVPLSMDEGFSMSPERVESLITQDTRVIIMNSPSNPTGSVMGKDDVKG 184
Query: 190 IADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVV 249
IA+IA+D ++ I+SDE YE IY D KHY +F +N ++ N FSKT+AMTG R+G+V
Sbjct: 185 IAEIAEDNDLIIISDEIYEKIIY-DGKHYSPAQFT-DNALIVNGFSKTYAMTGLRIGYVA 242
Query: 250 APSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLK 309
+II+E++K+H Y S Q A + A+R ++ VK+M E+ RR L+ + L
Sbjct: 243 GCEDIIEELLKVHQYNTACAPSISQYAALAAIRGPQN--CVKDMVDEFRRRRDLMFRSLT 300
Query: 310 EMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISY 369
+M G+ P GAFY+FP D SE+F++ LE A V V+PG+AFG G+GY+R+SY
Sbjct: 301 DM-GLECVLPGGAFYMFPYAGD----SEEFTKLSLE-AGVAVVPGSAFGNEGKGYIRMSY 354
Query: 370 ATSREKLMEAMDRME 384
ATS E + EAM+R++
Sbjct: 355 ATSYELIEEAMERLK 369
>gi|11499215 aspartate aminotransferase (aspB-3) [Archaeoglobus fulgidus]
>gi|7447819|pir||F69452 probable aspartate transaminase
(EC 2.6.1.1) aspB3 AF1623 [similarity] - Archaeoglobus
fulgidus >gi|2648929|gb|AAB89620.1| (AE000990) aspartate
aminotransferase (aspB-3) [Archaeoglobus fulgidus]
Length = 390
Score = 294 bits (745), Expect = 1e-78
Identities = 162/383 (42%), Positives = 233/383 (60%), Gaps = 11/383 (2%)
Query: 9 IAERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPN 68
+A RV +K S IR F+ ++VISLG+GEPDF P I+E +L++G+T YT N
Sbjct: 13 LARRVEELKPSGIRRFFDLVVGRDDVISLGVGEPDFPVPWRIREEMIYSLEKGYTSYTSN 72
Query: 69 AGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVS 128
G+ +LRE + EYY +F V E V++T+G EG +A +L+E GD LIP+P +VS
Sbjct: 73 LGLPELREGIAEYYTRF-GVKALPEQVMVTSGVSEGVDIAIRALIEPGDAALIPEPCYVS 131
Query: 129 YVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAK 188
Y ++ + V IP E F + L++ K +++V+NYP NPTG + K+ +
Sbjct: 132 YKPLVEICGGEAVTIPTAPE--FRLTYEMLMQYRDAKAKILVLNYPANPTGVSYSKKELE 189
Query: 189 AIADIAQDYNIYILSDEPYEHFIYDDAKHYPM--LKFAPENTILANSFSKTFAMTGWRLG 246
IAD + ++ +LSDE Y Y +H M L + ++ N FSK FAMTG R+G
Sbjct: 190 EIADAVNELDLIVLSDEIYAELTYT-GRHVSMAALNGMEDRVVIFNGFSKAFAMTGMRVG 248
Query: 247 FVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLK 306
+V+AP +I M+K+H Y + Q+ +EALRS + V+ MR EY RR V+K
Sbjct: 249 YVIAPPDIFAGMLKIHQYCMLCAPITGQIGAIEALRSLDE---VERMRAEYMRRRNFVVK 305
Query: 307 RLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVR 366
RL E+ +K+P+GAFY FP I TGMSSE+F+E LL + V V+PG AFG+ GEGYVR
Sbjct: 306 RLSEI--FEIKKPEGAFYAFPKISSTGMSSEEFAEKLLLEKSVAVVPGNAFGECGEGYVR 363
Query: 367 ISYATSREKLMEAMDRMEKALSE 389
++YA EKL EAMDR+++ + E
Sbjct: 364 LAYAVKFEKLKEAMDRIKEFVEE 386
>dbj|BAB07069.1| (AP001518) aspartate aminotransferase [Bacillus halodurans]
Length = 393
Score = 293 bits (741), Expect = 3e-78
Identities = 152/378 (40%), Positives = 233/378 (61%), Gaps = 7/378 (1%)
Query: 9 IAERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPN 68
++ RV I+ S IR F+ ASKMEN+ISLG+GEPDF TP N++EA +++ G+T Y+ N
Sbjct: 11 LSTRVQSIQPSGIRRFFDLASKMENIISLGVGEPDFVTPWNVREASISSMERGFTAYSAN 70
Query: 69 AGIQQLREAVVEYYKKFYDVDIDVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
AGI +LREA+ Y + + + D E+ +++T GA E + ++++ GDEV++ +P+FV
Sbjct: 71 AGIIELREAISRYLYERFHIGYDPESEILVTVGASEAIDIGMRAIIDEGDEVIVVEPSFV 130
Query: 128 SYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVA 187
SY +A PV + + +F P ++ +T +T+ I++ +PNNPTG+ + KE
Sbjct: 131 SYAPLVTMAGGVPVPVGTHIDTDFQVTPAQIEAAITPRTKAIILCFPNNPTGSIMGKEEL 190
Query: 188 KAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKF--APENTILANSFSKTFAMTGWRL 245
+A+A + ++ + SDE Y Y D H + E T+L + FSK FAMTGWRL
Sbjct: 191 EAVAKVISGNDLIVFSDEIYAELTY-DGTHVSLASMDGMRERTVLISGFSKAFAMTGWRL 249
Query: 246 GFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVL 305
G+V AP +I+ M+K+H Y + + Q +EAL E V M + Y +RR V+
Sbjct: 250 GYVCAPDDILSAMLKIHQYSLMCAPTMAQHGALEAL--ETGMDDVHRMVQSYRQRRNFVV 307
Query: 306 KRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYV 365
K E+ G+ P GAFY FPS+K+TG++SE+F+E LL + V V+PG FG+ GEG++
Sbjct: 308 KTFTEI-GLTCPMPGGAFYAFPSVKETGLTSEEFAERLLMEEHVAVVPGNVFGEGGEGHI 366
Query: 366 RISYATSREKLMEAMDRM 383
R SYATS E L A++R+
Sbjct: 367 RCSYATSMEHLETALERI 384
>pir||C33496 hisC homolog - Bacillus subtilis
Length = 393
Score = 282 bits (715), Expect = 3e-75
Identities = 156/370 (42%), Positives = 226/370 (60%), Gaps = 6/370 (1%)
Query: 16 IKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLR 75
I+ S IR+ ++ E+VISL IG+PDF TP ++K A K+A+DE T YTPNAG +LR
Sbjct: 12 IEISGIRKFSNLVAQHEDVISLTIGQPDFFTPHHVKAAAKKAIDENVTSYTPNAGYLELR 71
Query: 76 EAVVEYYKKFYDVDIDVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAK 134
+AV Y KK D + D E+ +IIT GA + AF ++L GDEV++P P + Y
Sbjct: 72 QAVQLYMKKKADFNYDAESEIIITTGASQAIDAAFRTILSPGDEVIMPGPIYPGYEPIIN 131
Query: 135 LAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIA 194
L AKPV + + F + + +T T+ +V+ YP+NPTG TL +E K+IA +
Sbjct: 132 LCGAKPVIVDTTS-HGFKLTARLIEDALTPNTKCVVLPYPSNPTGVTLSEEELKSIAALL 190
Query: 195 QDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPSEI 254
+ N+++LSDE Y YD HY + + + TI+ N SK+ MTGWR+GF+ AP +I
Sbjct: 191 KGRNVFVLSDEIYSELTYD-RPHYSIATYLRDQTIVINGLSKSHTMTGWRIGFLFAPKDI 249
Query: 255 IKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGI 314
K ++K+H Y + +S Q A +EA+ + + MR++Y +R V RL M G+
Sbjct: 250 AKHILKVHQYNVSCASSISQKAALEAVTN--GFDDALIMREQYKKRLDYVYDRLVSM-GL 306
Query: 315 RVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSRE 374
V +P GAFY+FPSIK GM+S FS LLE A V ++PG++F GEGYVR+S+A S +
Sbjct: 307 DVVKPSGAFYIFPSIKSFGMTSFDFSMALLEDAGVALVPGSSFSTYGEGYVRLSFACSMD 366
Query: 375 KLMEAMDRME 384
L E +DR+E
Sbjct: 367 TLREGLDRLE 376
>pir||C69672 probable aspartate transaminase (EC 2.6.1.-) patA [similarity] -
Bacillus subtilis >gi|2633771|emb|CAB13273.1| (Z99111)
aminotransferase [Bacillus subtilis]
Length = 392
Score = 279 bits (706), Expect = 4e-74
Identities = 156/370 (42%), Positives = 227/370 (61%), Gaps = 7/370 (1%)
Query: 16 IKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLR 75
I+ S IR+ ++ E+VISL IG+PDF TP ++K A K+A+DE T YTPNAG +LR
Sbjct: 12 IEISGIRKFSNLVAQHEDVISLTIGQPDFFTPHHVKAAAKKAIDENVTSYTPNAGYLELR 71
Query: 76 EAVVEYYKKFYDVDIDVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAK 134
+AV Y KK D + D E+ +IIT GA + AF ++L GDEV++P P + Y
Sbjct: 72 QAVQLYMKKKADFNYDAESEIIITTGA-QAIDAAFRTILSPGDEVIMPGPIYPGYEPIIN 130
Query: 135 LAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIA 194
L AKPV + + F + + +T T+ +V+ YP+NPTG TL +E K+IA +
Sbjct: 131 LCGAKPVIVD-TTSHGFKLTARLIEDALTPNTKCVVLPYPSNPTGVTLSEEELKSIAALL 189
Query: 195 QDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPSEI 254
+ N+++LSDE Y Y D HY + + + TI+ N SK+ +MTGWR+GF+ AP +I
Sbjct: 190 KGRNVFVLSDEIYSELTY-DRPHYSIATYLRDQTIVINGLSKSHSMTGWRIGFLFAPKDI 248
Query: 255 IKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGI 314
K ++K+H Y + +S Q A +EA+ + + MR++Y +R V RL M G+
Sbjct: 249 AKHILKVHQYNVSCASSISQKAALEAVTN--GFDDALIMREQYKKRLDYVYDRLVSM-GL 305
Query: 315 RVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSRE 374
V +P GAFY+FPSIK GM+S FS LLE A V ++PG++F GEGYVR+S+A S +
Sbjct: 306 DVVKPSGAFYIFPSIKSFGMTSFDFSMALLEDAGVALVPGSSFSTYGEGYVRLSFACSMD 365
Query: 375 KLMEAMDRME 384
L E +DR+E
Sbjct: 366 TLREGLDRLE 375
>sp|P16524|PATA_BACSU PUTATIVE AMINOTRANSFERASE A >gi|2632221|emb|CAA10863.1| (AJ222587)
PatA protein [Bacillus subtilis]
Length = 392
Score = 279 bits (705), Expect = 5e-74
Identities = 156/370 (42%), Positives = 227/370 (61%), Gaps = 7/370 (1%)
Query: 16 IKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLR 75
I+ S IR+ ++ E+VISL IG+PDF TP ++K A K+A+DE T YTPNAG +LR
Sbjct: 12 IEISGIRKFSNLVAQHEDVISLTIGQPDFFTPHHVKAAAKKAIDENVTSYTPNAGYLELR 71
Query: 76 EAVVEYYKKFYDVDIDVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAK 134
+AV Y KK D + D E+ +IIT GA + AF ++L GDEV++P P + Y
Sbjct: 72 QAVQLYMKKKADFNYDAESEIIITTGA-QAIDAAFRTILSPGDEVIMPGPIYPGYEPIIN 130
Query: 135 LAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIA 194
L AKPV + + F + + +T T+ +V+ YP+NPTG TL +E K+IA +
Sbjct: 131 LCGAKPVIVD-TTSHGFKLTARLIEDALTPNTKCVVLPYPSNPTGVTLSEEELKSIAALL 189
Query: 195 QDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPSEI 254
+ N+++LSDE Y Y D HY + + + TI+ N SK+ +MTGWR+GF+ AP +I
Sbjct: 190 KGRNVFVLSDEIYSELTY-DRPHYSIATYLRDQTIVINGLSKSHSMTGWRIGFLFAPKDI 248
Query: 255 IKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGI 314
K ++K+H Y + +S Q A +EA+ + + MR++Y +R V RL M G+
Sbjct: 249 AKHILKVHQYNVSCASSISQKAALEAVTNGLDDALI--MREQYKKRLDYVYDRLVSM-GL 305
Query: 315 RVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSRE 374
V +P GAFY+FPSIK GM+S FS LLE A V ++PG++F GEGYVR+S+A S +
Sbjct: 306 DVVKPSGAFYIFPSIKSFGMTSFDFSMALLEDAGVALVPGSSFSTYGEGYVRLSFACSMD 365
Query: 375 KLMEAMDRME 384
L E +DR+E
Sbjct: 366 TLREGLDRLE 375
>pir||D72450 probable aspartate transaminase (EC 2.6.1.1) APE2248 [similarity] -
Aeropyrum pernix (strain K1) >gi|5105949|dbj|BAA81260.1|
(AP000064) 409aa long hypothetical aspartate
aminotransferase [Aeropyrum pernix]
Length = 409
Score = 276 bits (698), Expect = 3e-73
Identities = 161/395 (40%), Positives = 232/395 (57%), Gaps = 15/395 (3%)
Query: 9 IAERVILIKRSKIRELFERASKM----ENVISLGIGEPDFDTPKNIKEACKRALDEGWTH 64
I ERV+ I+ A K+ VIS GIG+PDF TP +I+EA K+ALDEG+T
Sbjct: 14 IQERVVEIEGETAFAYLAVARKLIQEGRRVISFGIGQPDFPTPHHIREAAKKALDEGFTG 73
Query: 65 YTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDP 124
YT AGI +LREA+ Y Y D+ E VI T GA +L L GDEV+IPDP
Sbjct: 74 YTETAGIPELREAIAWYLNSRYGADVSPEEVIATTGAKTAIFLGMALYLRPGDEVIIPDP 133
Query: 125 AFVSYVEDAKLAEAKPVRIPLREEN--NFMPDPDELLELVTKKTRMIVINYPNNPTGATL 182
++ +Y + AKL A+PV +P++ E F D + + V++KTRMIV+N P+NPTG+
Sbjct: 134 SYYAYAQVAKLFGARPVYVPMKFEPGLGFRFDIEGIERAVSEKTRMIVVNNPHNPTGSVF 193
Query: 183 DKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAP--ENTILANSFSKTFAM 240
+ +AI DIA+ + IL+DE Y++F+Y + L EN + N FSKTF+M
Sbjct: 194 PPDQVEAIHDIARRRGLIILADEIYDNFLYTEKPFKSTLSLPDWRENLVYVNGFSKTFSM 253
Query: 241 TGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNER 300
TGWRLG+VV E+I + + L I S Q AGV ALR + W V+EM +E+ R
Sbjct: 254 TGWRLGYVVLRREVIPKALDLAVTIYSCPPSIAQKAGVAALRGD--WGPVREMVEEFRSR 311
Query: 301 RKLVLKRLKEMPGIRVKEPKGAFYVFPSI----KDTGMSSEKFSEWLLEKARVVVIPGTA 356
+++ L + GI P+GAFY+FP + + TG+S E+ +E LL V+V+PGT+
Sbjct: 312 ARILYDILSQAEGIEPYLPEGAFYMFPRVAGLLRKTGLSVEQLAEKLLYSYGVLVLPGTS 371
Query: 357 FGK-MGEGYVRISYATSREKLMEAMDRMEKALSEL 390
F + +G +VR+S+AT+ + E + + +A EL
Sbjct: 372 FPESVGREHVRLSFATATSDVKEGAEIIVRASREL 406
>gi|11499712 aspartate aminotransferase (aspB-2) [Archaeoglobus fulgidus]
>gi|7447817|pir||A69516 probable aspartate transaminase
(EC 2.6.1.1) aspB2 AF2129 [similarity] - Archaeoglobus
fulgidus >gi|2648397|gb|AAB89121.1| (AE000957) aspartate
aminotransferase (aspB-2) [Archaeoglobus fulgidus]
Length = 379
Score = 272 bits (689), Expect = 4e-72
Identities = 151/384 (39%), Positives = 235/384 (60%), Gaps = 17/384 (4%)
Query: 10 AERVILIKRSKIRELFERASKME----NVISLGIGEPDFDTPKNIKEACKRALDEGWTHY 65
A R+ +++ S + A +++ +V+ + +GEPDF TP I EA +A+ EG Y
Sbjct: 6 ANRIEVVQPSATLRVSTMAKELKREGKDVVDMSVGEPDFPTPDFIIEAAYKAMKEGKVFY 65
Query: 66 TPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPA 125
TP G+ +L +A+VE + +D+ EN+I+T GA + A LL+ GDEV++ DP+
Sbjct: 66 TPTKGVPELIDAIVEKLRNENGIDVGAENIIVTPGAKYAIFEAMMCLLQEGDEVILLDPS 125
Query: 126 FVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKE 185
+VSY +A AKPV +P E F P E + +T T+MIV+N P+NP G KE
Sbjct: 126 WVSYEACILMAGAKPVWVP--HEEGFEDAPIE--DYITSNTKMIVVNTPSNPLGVVYPKE 181
Query: 186 VAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPM--LKFAPENTILANSFSKTFAMTGW 243
K + D+A D +I ++SDE YE I+ + +HY + + E TI N FSKT++MTGW
Sbjct: 182 FLKKVRDLAVDKDILVMSDEIYEKIIF-EGEHYSLAAMDGMLERTITINGFSKTYSMTGW 240
Query: 244 RLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKL 303
RLG+ AP IIK M ++ ++ + + SF+Q AGV AL+ ++S+ +KE+ +E+ RR +
Sbjct: 241 RLGYAAAPEWIIKLMNRMQSHSVSHPTSFVQYAGVAALKGDQSF--IKEIVEEFRARRDM 298
Query: 304 VLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEG 363
++ +L EM GI PKGAFY+F ++ G S +F E L++ V + PG+AFG +
Sbjct: 299 IMAKLDEM-GIEYAPPKGAFYIFMNV---GRDSNEFCEEFLKREYVALTPGSAFGVAYKS 354
Query: 364 YVRISYATSREKLMEAMDRMEKAL 387
+VR+SYATSRE++ E + R+E+ L
Sbjct: 355 WVRLSYATSRERIGEFLSRLERFL 378
>sp|Q56232|AAT_THETH ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|2120597|pir||JC4537 aspartate transaminase (EC
2.6.1.1) [validated] - Thermus aquaticus (strain HB8)
>gi|5821839|pdb|1BKG|A Chain A, Aspartate
Aminotransferase From Thermus Thermophilus With Maleate
>gi|5821840|pdb|1BKG|B Chain B, Aspartate
Aminotransferase From Thermus Thermophilus With Maleate
>gi|5821841|pdb|1BKG|C Chain C, Aspartate
Aminotransferase From Thermus Thermophilus With Maleate
>gi|5821842|pdb|1BKG|D Chain D, Aspartate
Aminotransferase From Thermus Thermophilus With Maleate
>gi|1255699|dbj|BAA07487.1| (D38459) aspartate
aminotransferase [Thermus thermophilus]
>gi|1587013|prf||2205299A Asp aminotransferase [Thermus
aquaticus thermophilus]
Length = 385
Score = 271 bits (685), Expect = 1e-71
Identities = 141/356 (39%), Positives = 220/356 (61%), Gaps = 6/356 (1%)
Query: 33 NVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYDVDIDV 92
++++L GEPDFDTP+++KEA +RAL +G T Y P AGI +LREA+ E +++ + +
Sbjct: 32 DLVALTAGEPDFDTPEHVKEAARRALAQGKTKYAPPAGIPELREALAEKFRRENGLSVTP 91
Query: 93 ENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENNFM 152
E I+T G + + F+++L+ GDEV++ P +VSY E + A V + E F+
Sbjct: 92 EETIVTVGGKQALFNLFQAILDPGDEVIVLSPYWVSYPEMVRFAGGVVVEVETLPEEGFV 151
Query: 153 PDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHFIY 212
PDP+ + +T +T+ +V+N PNNPTGA KEV +A+A +A +++ Y++SDE YEH +Y
Sbjct: 152 PDPERVRRAITPRTKALVVNSPNNPTGAVYPKEVLEALARLAVEHDFYLVSDEIYEHLLY 211
Query: 213 DDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASF 272
+ +H+ + APE+T+ N +K FAMTGWR+G+ P E+IK M + + + +
Sbjct: 212 -EGEHFSPGRVAPEHTLTVNGAAKAFAMTGWRIGYACGPKEVIKAMASVSSQSTTSPDTI 270
Query: 273 IQVAGVEALRSEESWKAVKEMRKE-YNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIKD 331
Q A +EAL ++E+ +A EM +E Y RR L+L+ L + G++ P GAFYV
Sbjct: 271 AQWATLEALTNQEASRAFVEMAREAYRRRRDLLLEGLTAL-GLKAVRPSGAFYVLMDTSP 329
Query: 332 TGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAMDRMEKAL 387
+ +E LLE A V V+PGT F G+VR+SYATS E L +A++R + L
Sbjct: 330 IAPDEVRAAERLLE-AGVAVVPGTDFAAF--GHVRLSYATSEENLRKALERFARVL 382
>pdb|1BJW|A Chain A, Aspartate Aminotransferase From Thermus Thermophilus
>gi|5821837|pdb|1BJW|B Chain B, Aspartate
Aminotransferase From Thermus Thermophilus
Length = 382
Score = 268 bits (679), Expect = 6e-71
Identities = 140/356 (39%), Positives = 219/356 (61%), Gaps = 6/356 (1%)
Query: 33 NVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYDVDIDV 92
++++L GEPDFDTP+++KEA +RAL +G T Y P AGI +LREA+ E +++ + +
Sbjct: 32 DLVALTAGEPDFDTPEHVKEAARRALAQGKTKYAPPAGIPELREALAEKFRRENGLSVTP 91
Query: 93 ENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENNFM 152
E I+T G + + F+++L+ GDEV++ P +VSY E + A V + E F+
Sbjct: 92 EETIVTVGGKQALFNLFQAILDPGDEVIVLSPYWVSYPEMVRFAGGVVVEVETLPEEGFV 151
Query: 153 PDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHFIY 212
PDP+ + +T +T+ +V+N PNNPTGA KEV +A+A +A +++ Y++SDE YEH +Y
Sbjct: 152 PDPERVRRAITPRTKALVVNSPNNPTGAVYPKEVLEALARLAVEHDFYLVSDEIYEHLLY 211
Query: 213 DDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASF 272
+ +H+ + APE+T+ N + FAMTGWR+G+ P E+IK M + + + +
Sbjct: 212 -EGEHFSPGRVAPEHTLTVNGAAXAFAMTGWRIGYACGPKEVIKAMASVSSQSTTSPDTI 270
Query: 273 IQVAGVEALRSEESWKAVKEMRKE-YNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIKD 331
Q A +EAL ++E+ +A EM +E Y RR L+L+ L + G++ P GAFYV
Sbjct: 271 AQWATLEALTNQEASRAFVEMAREAYRRRRDLLLEGLTAL-GLKAVRPSGAFYVLMDTSP 329
Query: 332 TGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAMDRMEKAL 387
+ +E LLE A V V+PGT F G+VR+SYATS E L +A++R + L
Sbjct: 330 IAPDEVRAAERLLE-AGVAVVPGTDFAAF--GHVRLSYATSEENLRKALERFARVL 382
>sp|O33822|AAT_THEAQ ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|7447805|pir||JC5775 aspartate transaminase (EC
2.6.1.1) - Thermus aquaticus >gi|2266762|emb|CAA67877.1|
(X99521) aspartate aminotransferase [Thermus aquaticus]
Length = 383
Score = 268 bits (677), Expect = 1e-70
Identities = 148/384 (38%), Positives = 230/384 (59%), Gaps = 10/384 (2%)
Query: 9 IAERVILIKRSKIRELFERASKME----NVISLGIGEPDFDTPKNIKEACKRALDEGWTH 64
+++RV +K S + RA ++ ++++L GEPDFDTP+++KEA +RAL +G T
Sbjct: 4 LSQRVKSMKPSATVAVNARALELRRKGVDLVALTAGEPDFDTPEHVKEAGRRALAQGKTK 63
Query: 65 YTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDP 124
Y P AGI +LREAV E +++ +++ E I+T G + + F+++L+ GDEV++ P
Sbjct: 64 YAPPAGIPELREAVAEKFRRENGLEVTPEETIVTVGGKQALFNLFQAILDPGDEVIVLAP 123
Query: 125 AFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDK 184
+VSY E + A PV +P E F+PDP+ + +T +T+ +V+N PNNPTG +
Sbjct: 124 YWVSYPEMVRFAGGVPVEVPTLPEEGFVPDPERVRRAITPRTKALVVNSPNNPTGVVYPE 183
Query: 185 EVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWR 244
EV +A+A++A ++ Y++SDE YEH IY+ A H+ APE+TI N +K FAMTGWR
Sbjct: 184 EVLRALAEMALQHDFYLVSDEIYEHLIYEGA-HFSPGTLAPEHTITVNGAAKAFAMTGWR 242
Query: 245 LGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKE-YNERRKL 303
+G+ P +IK M + + + + Q A +EAL + E+ A M +E Y +RR L
Sbjct: 243 IGYACGPKAVIKAMADVSSQSTTSPDTIAQWATLEALTNREASMAFIAMAREAYRKRRDL 302
Query: 304 VLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEG 363
+L+ L + G+ P GAFYV + + +E LL A V V+PGT F G
Sbjct: 303 LLEGLSRI-GLEAVRPSGAFYVLMDTSPFAPNEVEAAERLL-MAGVAVVPGTEFAAF--G 358
Query: 364 YVRISYATSREKLMEAMDRMEKAL 387
+VR+SYAT E L +A++R +AL
Sbjct: 359 HVRLSYATGEENLKKALERFAQAL 382
>dbj|BAB05414.1| (AP001512) aspartate aminotransferase [Bacillus halodurans]
Length = 395
Score = 266 bits (674), Expect = 2e-70
Identities = 141/387 (36%), Positives = 234/387 (60%), Gaps = 16/387 (4%)
Query: 9 IAERVILIKRSKIRELFERASKME----NVISLGIGEPDFDTPKNIKEACKRALDEGWTH 64
+A+RV + S + +A +++ +VI LG GEPDF+TP+ I +A R+++EG T
Sbjct: 3 LAKRVSTLTPSSTLAITAKAKELKEQGHDVIGLGAGEPDFNTPQYIIDAAVRSMEEGHTK 62
Query: 65 YTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDP 124
YTP+ G+ +L+EA++E +K+ + + + + GA Y F++LL GDEV+IP P
Sbjct: 63 YTPSGGLPKLKEAIIEKFKQDQGLTYTAKEIFVGTGAKHVLYTLFQALLNEGDEVIIPSP 122
Query: 125 AFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDK 184
+VSY E KLA +PV + +E N+F P +L ++T +T+ I+IN P+NPTG+ +
Sbjct: 123 YWVSYPEQVKLAGGEPVFVEGKESNDFKLTPAQLEPVLTDRTKAIIINSPSNPTGSLYTQ 182
Query: 185 EVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAP---ENTILANSFSKTFAMT 241
E A+ ++ +N+ I+SDE YE +YD AKH + + +P ENT++ N SK+ +MT
Sbjct: 183 EELAALGEVCLKHNVLIISDEIYEKLVYDGAKHTSVAEISPQLKENTVVINGVSKSHSMT 242
Query: 242 GWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERR 301
GWR+G+ P +I+ M L ++ N + Q + A ++ +V++MR + ER
Sbjct: 243 GWRIGYAAGPEALIQAMTNLASHSTSNPTTSAQYGAIAAYTEDDG--SVEKMRVAFEERL 300
Query: 302 KLVLKRLKEMPGIRVKEPKGAFYVFPSIKD----TGMSS-EKFSEWLLEKARVVVIPGTA 356
+ +L +PG+ +PKGAFY+FP++++ TG + + F + LLE+ +V ++PG+
Sbjct: 301 HTIYDKLVAIPGVSCVKPKGAFYLFPNVEEAAALTGHETVDDFVKVLLEEEKVALVPGSG 360
Query: 357 FGKMGEGYVRISYATSREKLMEAMDRM 383
FG VR+SYATS E L A+DR+
Sbjct: 361 FG--APDNVRLSYATSLELLEAAIDRI 385
>sp|Q59228|AAT_BACST ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|1103380|emb|CAA63799.1| (X93600) aspartate
transaminase [Bacillus stearothermophilus]
Length = 393
Score = 266 bits (672), Expect = 4e-70
Identities = 138/389 (35%), Positives = 232/389 (59%), Gaps = 16/389 (4%)
Query: 9 IAERVILIKRSKIRELFERASKME----NVISLGIGEPDFDTPKNIKEACKRALDEGWTH 64
+A+RV + S + E+A +++ +VI LG GEPDF+TP++I +A +A++EG T
Sbjct: 3 LAKRVASLTPSATLAITEKAKELKAAGHDVIGLGAGEPDFNTPQHILDAAIKAMNEGHTK 62
Query: 65 YTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDP 124
YTP+ G+ L+E +++ + + +D + VI+ GA Y F+ LL+ GDEV+IP P
Sbjct: 63 YTPSGGLPALKEEIIKKFARDQGLDYEPAEVIVCVGAKHALYTLFQVLLDEGDEVIIPTP 122
Query: 125 AFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDK 184
+VSY E KLA PV + E+N+F P++L + +T +T+ ++IN P+NPTG
Sbjct: 123 YWVSYPEQVKLAGGVPVYVEGLEQNHFKITPEQLKQAITPRTKAVIINSPSNPTGMIYTA 182
Query: 185 EVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPE---NTILANSFSKTFAMT 241
E KA+ ++ + + I+SDE YE Y AKH + + +PE T++ N SK+ +MT
Sbjct: 183 EELKALGEVCLAHGVLIVSDEIYEKLTYGGAKHVSIAELSPELKAQTVIINGVSKSHSMT 242
Query: 242 GWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERR 301
GWR+G+ P +IIK M L ++ N S Q A + A + + V++MR+ + +R
Sbjct: 243 GWRIGYAAGPKDIIKAMTDLASHSTSNPTSIAQYAAIAAYSGPQ--EPVEQMRQAFEQRL 300
Query: 302 KLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSS-----EKFSEWLLEKARVVVIPGTA 356
++ +L ++PG +P+GAFY+FP+ ++ + ++F LLE+A+V ++PG+
Sbjct: 301 NIIYDKLVQIPGFTCVKPQGAFYLFPNAREAAAMAGCRTVDEFVAALLEEAKVALVPGSG 360
Query: 357 FGKMGEGYVRISYATSREKLMEAMDRMEK 385
FG VR+SYATS + L A++R+ +
Sbjct: 361 FG--APDNVRLSYATSLDALETAVERIHR 387
>emb|CAC11669.1| (AL445064) probable aspartate aminotransferase [Thermoplasma
acidophilum]
Length = 377
Score = 265 bits (670), Expect = 7e-70
Identities = 155/385 (40%), Positives = 225/385 (58%), Gaps = 12/385 (3%)
Query: 8 FIAERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTP 67
+I E + + + +L ++ K+ N GIGEPDF TP+ I + +G THYTP
Sbjct: 3 YINESATVSASNNVEKLRKQGLKIYN---FGIGEPDFTTPEGIIDYAFEMAKQGKTHYTP 59
Query: 68 NAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
+AGI +LRE + K +D + ENV++T + G LA +L GDEV+IPDP +V
Sbjct: 60 SAGIMELREKIASKLKTRNRIDANAENVLVTPTKF-GINLAMMVILNPGDEVIIPDPYYV 118
Query: 128 SYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVA 187
SY + KLA KPV P+R +++ D DE+ + VT +TR I++N PNNPTG L ++
Sbjct: 119 SYPDIVKLAGGKPV--PVRTTDDYDIDLDEMRKFVTPRTRAIILNNPNNPTGKVLSEKEI 176
Query: 188 KAIADIAQDYNIYILSDEPYEHFIYDDAKHYP--MLKFAPENTILANSFSKTFAMTGWRL 245
+ + D A + +IYI+SDE YE IY+ + + P M K A E+TI N FSK +AMTGWR+
Sbjct: 177 RDLVDFALENDIYIVSDEIYEDLIYEGSLYSPASMGKEAFEHTITLNGFSKGYAMTGWRI 236
Query: 246 GFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVL 305
G+ VA EI++ + I +S Q A + AL ES MR E+ +RR L
Sbjct: 237 GYFVATEEIVEAANIIQQQTITCASSISQYAALRALDDNES---PARMRSEFRKRRDLAY 293
Query: 306 KRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYV 365
L E ++V +P+GAFY+FP + SEK +E LL + VVV PG+AFG G +
Sbjct: 294 GILSESTDMKVHKPEGAFYMFPGY-SKDIPSEKIAEMLLNQEHVVVTPGSAFGDRGRHHF 352
Query: 366 RISYATSREKLMEAMDRMEKALSEL 390
RIS+ATS + + E ++R+ K + L
Sbjct: 353 RISFATSEDIIKEGLERLVKFMHTL 377
>sp|P23034|AAT_BACSP ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|98167|pir||A38621 aspartate transaminase (EC
2.6.1.1) - Bacillus sp. (strain YM-2)
>gi|142538|gb|AAA22250.1| (M59430) aspartate
aminotransferase [Bacillus sp.]
Length = 392
Score = 264 bits (667), Expect = 1e-69
Identities = 144/392 (36%), Positives = 231/392 (58%), Gaps = 16/392 (4%)
Query: 6 KYFIAERVILIKRSKIRELFERASKME----NVISLGIGEPDFDTPKNIKEACKRALDEG 61
K +A RV + S + +A +M+ +VI LG GEPDF+TP+NI +A ++ +G
Sbjct: 2 KELLANRVKTLTPSTTLAITAKAKEMKAQGIDVIGLGAGEPDFNTPQNIMDAAIDSMQQG 61
Query: 62 WTHYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLI 121
+T YTP+ G+ L++A++E +K+ ++ +I+ GA Y F+ +L GDEV+I
Sbjct: 62 YTKYTPSGGLPALKQAIIEKFKRDNQLEYKPNEIIVGVGAKHVLYTLFQVILNEGDEVII 121
Query: 122 PDPAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGAT 181
P P +VSY E KLA PV I E N+ ++L +T KT+ ++IN P+NPTG
Sbjct: 122 PIPYWVSYPEQVKLAGGVPVYIEATSEQNYKITAEQLKNAITDKTKAVIINSPSNPTGMV 181
Query: 182 LDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPE---NTILANSFSKTF 238
+E + IA IA + NI I+SDE YE +Y+ A+H+ + + + E TI+ N SK+
Sbjct: 182 YTREELEDIAKIALENNILIVSDEIYEKLLYNGAEHFSIAQISEEVKAQTIVINGVSKSH 241
Query: 239 AMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYN 298
+MTGWR+G+ ++II M L ++ N + Q A +EA + +V+EMRK +
Sbjct: 242 SMTGWRIGYAAGNADIINAMTDLASHSTSNPTTASQYAAIEAYNGPQD--SVEEMRKAFE 299
Query: 299 ERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIKD----TGMSS-EKFSEWLLEKARVVVIP 353
R + + +L +PG +V +P+GAFY+ P + + TG +S ++F+ LL +A V VIP
Sbjct: 300 SRLETIYPKLSAIPGFKVVKPQGAFYLLPDVSEAAQKTGFASVDEFASALLTEANVAVIP 359
Query: 354 GTAFGKMGEGYVRISYATSREKLMEAMDRMEK 385
G+ FG +RISYATS + EA++R+++
Sbjct: 360 GSGFG--APSTIRISYATSLNLIEEAIERIDR 389
>pir||D75496 aspartate transaminase (EC 2.6.1.1) DR0623 [similarity] -
Deinococcus radiodurans (strain R1)
>gi|6458322|gb|AAF10201.1|AE001920_4 (AE001920)
aspartate aminotransferase [Deinococcus radiodurans]
Length = 388
Score = 263 bits (665), Expect = 3e-69
Identities = 145/381 (38%), Positives = 222/381 (58%), Gaps = 9/381 (2%)
Query: 9 IAERVILIKRSKIRELFERASKME----NVISLGIGEPDFDTPKNIKEACKRALDEGWTH 64
++ R +K S + RA +++ +VIS+ +GEPDFDTP ++K A A++EG T
Sbjct: 7 LSARAQSLKPSATVAVTSRALELQRQGLDVISMSVGEPDFDTPPHVKAAGIAAIEEGKTK 66
Query: 65 YTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDP 124
YTP +GI +LREA+ +++ +D V +T+G + + AF +LL GDEVLIP P
Sbjct: 67 YTPVSGIPELREAISAKFRRENGLDYAPNAVTVTSGGKQALFNAFFALLNPGDEVLIPAP 126
Query: 125 AFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDK 184
+VSY E L A PV +P + F DPD L +T +TRM+++N P NPTGA
Sbjct: 127 HWVSYPEMVALTGAVPVTVPTTPQQGFQLDPDALAAAITPRTRMVILNSPGNPTGAVFPP 186
Query: 185 EVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWR 244
E +A+AD+A + + I++DE YEH +Y DA+ + +APE+T+ N SK +AMTGWR
Sbjct: 187 ETLRAVADLATQHGLMIVTDEIYEHLVY-DAEQVSIGTYAPEHTLTINGASKAYAMTGWR 245
Query: 245 LGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEAL-RSEESWKAVKEMRKEYNERRKL 303
+G+ P E+I M L + N +S Q A + AL + EE+ + + R Y ERR
Sbjct: 246 IGYAGGPREVIAAMNALQSQSTSNASSVSQYAALAALEQHEETMRFIDRARTAYRERRDR 305
Query: 304 VLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEG 363
++ L + G+ P+GAFYV + + + +L++A+V V+PGT F G+
Sbjct: 306 IVAGLNAL-GLPTPTPQGAFYVMADTRAIHTDELEAARIILDEAQVAVVPGTDFAAPGQ- 363
Query: 364 YVRISYATSREKLMEAMDRME 384
VR+SYATS + + E + R+E
Sbjct: 364 -VRLSYATSMDNIEEVLRRLE 383
>gb|AAD23617.1|AC007168_8 (AC007168) putative aspartate aminotransferase [Arabidopsis
thaliana]
Length = 406
Score = 263 bits (665), Expect = 3e-69
Identities = 155/400 (38%), Positives = 231/400 (57%), Gaps = 20/400 (5%)
Query: 9 IAERVILIKRSKIRELFERASKMEN----VISLGIGEPDFDTPKNIKEACKRALDEGWTH 64
++ RV +K SK + + A+ + VI L GEPDFDTPK + EA A+ EG+T
Sbjct: 3 LSPRVQSLKPSKTMVITDLAATLVQSGVPVIRLAAGEPDFDTPKVVAEAGINAIREGFTR 62
Query: 65 YTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDP 124
YT NAGI +LREA+ K+ + + ++++ GA + A ++ GDEV+IP P
Sbjct: 63 YTLNAGITELREAICRKLKEENGLSYAPDQILVSNGAKQSLLQAVLAVCSPGDEVIIPAP 122
Query: 125 AFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDK 184
+VSY E A+LA+A PV IP + NNF+ DP +L +T+K+R++++ P+NPTG+ K
Sbjct: 123 YWVSYTEQARLADATPVVIPTKISNNFLLDPKDLESKLTEKSRLLILCSPSNPTGSVYPK 182
Query: 185 EVAKAIAD-IAQDYNIYILSDEPYEHFIYDDAKH--YPMLKFAPENTILANSFSKTFAMT 241
+ + IA IA+ + +LSDE YEH IY A H + L E T+ N FSK FAMT
Sbjct: 183 SLLEEIARIIAKHPRLLVLSDEIYEHIIYAPATHTSFASLPDMYERTLTVNGFSKAFAMT 242
Query: 242 GWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEAL-RSEESWKAVKEMRKEYNER 300
GWRLG++ P I+ KL + +S Q AGV AL + + V EM K Y ER
Sbjct: 243 GWRLGYLAGPKHIVAACSKLQGQVSSGASSIAQKAGVAALGLGKAGGETVAEMVKAYRER 302
Query: 301 RKLVLKRLKEMPGIRVKEPKGAFYVF--------PSIKDTGM--SSEKFSEWLLEKARVV 350
R ++K L ++ G+++ EP+GAFY+F + G+ S + + L+K +V
Sbjct: 303 RDFLVKSLGDIKGVKISEPQGAFYLFIDFSAYYGSEAEGFGLINDSSSLALYFLDKFQVA 362
Query: 351 VIPGTAFGKMGEGYVRISYATSREKLMEAMDRMEKALSEL 390
++PG AFG + +RISYATS + L A++++ KAL L
Sbjct: 363 MVPGDAFG--DDSCIRISYATSLDVLQAAVEKIRKALEPL 400
>sp|P53001|AAT1_BACSU ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|7447803|pir||C69591 aspartate transaminase (EC
2.6.1.1) aspB [similarity] - Bacillus subtilis
>gi|1146246|gb|AAB38454.1| (L47709) aspartate
aminotransferase [Bacillus subtilis]
>gi|2634655|emb|CAB14153.1| (Z99115) aspartate
aminotransferase [Bacillus subtilis]
Length = 393
Score = 263 bits (664), Expect = 3e-69
Identities = 138/389 (35%), Positives = 229/389 (58%), Gaps = 16/389 (4%)
Query: 9 IAERVILIKRSKIRELFERASKME----NVISLGIGEPDFDTPKNIKEACKRALDEGWTH 64
+A+RV + S + +A +++ +VI LG GEPDF+TP++I +A R+++EG T
Sbjct: 3 LAKRVSALTPSTTLAITAKAKELKAAGHDVIGLGAGEPDFNTPQHIIDAAVRSMNEGHTK 62
Query: 65 YTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDP 124
YTP+ G+ +L+ ++ E +K+ +++ +I+ GA Y F+ +L+ DEV+IP P
Sbjct: 63 YTPSGGLAELKNSIAEKFKRDQNIEYKPSQIIVCTGAKHALYTLFQVILDEEDEVIIPTP 122
Query: 125 AFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDK 184
+VSY E KLA KPV + EEN+F P++L +T+KT+ IVIN P+NPTG +
Sbjct: 123 YWVSYPEQVKLAGGKPVYVEGLEENHFKISPEQLKNAITEKTKAIVINSPSNPTGVMYTE 182
Query: 185 EVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFA---PENTILANSFSKTFAMT 241
E A+ ++ +++I I+SDE YE Y KH + + + E T++ N SK+ +MT
Sbjct: 183 EELSALGEVCLEHDILIVSDEIYEKLTYGGKKHVSIAQLSDRLKEQTVIINGVSKSHSMT 242
Query: 242 GWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERR 301
GWR+G+ +IIK M L ++ N S Q + A + ++EMR+ + R
Sbjct: 243 GWRIGYAAGSEDIIKAMTNLASHSTSNPTSIAQYGAIAAYNGPS--EPLEEMREAFEHRL 300
Query: 302 KLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSS-----EKFSEWLLEKARVVVIPGTA 356
+ +L E+PG +P+GAFY+FP+ K+ S ++F + LLE+ +V ++PG+
Sbjct: 301 NTIYAKLIEIPGFSCVKPEGAFYLFPNAKEAAQSCGFKDVDEFVKALLEEEKVAIVPGSG 360
Query: 357 FGKMGEGYVRISYATSREKLMEAMDRMEK 385
FG VR+SYATS + L EA++R+++
Sbjct: 361 FGSPEN--VRLSYATSLDLLEEAIERIKR 387
>gb|AAB81842.1| (AF025665) aspartate aminotransferase [Thermus aquaticus]
Length = 383
Score = 258 bits (653), Expect = 6e-68
Identities = 144/384 (37%), Positives = 224/384 (57%), Gaps = 10/384 (2%)
Query: 9 IAERVILIKRSKIRELFERASKME----NVISLGIGEPDFDTPKNIKEACKRALDEGWTH 64
+++RV +K S + RA ++ ++++L GEPDFDTP ++KE +R L +G T
Sbjct: 4 LSQRVKSMKPSATVVVNARALELRRKGVDLVALTAGEPDFDTPHHVKERARRGLAQGKTK 63
Query: 65 YTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDP 124
Y P AGI +LREAV E ++ +++ E I+T G + + F+++L+ GDEV++ P
Sbjct: 64 YAPPAGIPELREAVAEKFRGENGLEVTPEETIVTVGGKQALFNLFQAILDPGDEVIVLAP 123
Query: 125 AFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDK 184
+VSY E + A PV +P E F+PDP+ + +T +T+ +V+N PNNPTG +
Sbjct: 124 YWVSYPEMVRFAGGVPVEVPTLPEEGFVPDPERVRRAITPRTKALVVNSPNNPTGVVYPE 183
Query: 185 EVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWR 244
EV +A+A++A ++ Y++SDE YEH IY+ A H+ APE+TI + FAMTGWR
Sbjct: 184 EVCEALAEMALQHDFYLVSDEIYEHLIYEGA-HFSPRHLAPEHTITVERAANAFAMTGWR 242
Query: 245 LGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKE-YNERRKL 303
+G+ P +IK M + + + + Q A +EAL + E+ A M +E Y +RR L
Sbjct: 243 IGYACGPKAVIKAMADVSSQSTTSPDTIAQWATLEALTNREASMAFIAMAREAYRKRRDL 302
Query: 304 VLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEG 363
+L+ L + G+ P GAFYV + + +E LL A V V+PGT F G
Sbjct: 303 LLEGLSRI-GLEAVRPSGAFYVLMDTSPFAPNEVEAAERLL-MAGVAVVPGTDFAAF--G 358
Query: 364 YVRISYATSREKLMEAMDRMEKAL 387
+VR+SYAT E L +A++R +AL
Sbjct: 359 HVRLSYATGEENLKKALERFAQAL 382
>gb|AAF06954.1|AF146529_1 (AF146529) aromatic amino acid aminotransferase [Lactococcus lactis
subsp. cremoris]
Length = 391
Score = 254 bits (643), Expect = 1e-66
Identities = 135/373 (36%), Positives = 225/373 (60%), Gaps = 9/373 (2%)
Query: 16 IKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLR 75
I+ S IR+ ++ S + ++I L +GEPDF TP+++K+A A++ +HYT AG+ +LR
Sbjct: 14 IEISLIRQFDQQVSSIPDIIKLTLGEPDFYTPEHVKQAGIAAIENNQSHYTGMAGLLELR 73
Query: 76 EAVVEYYKKFYDVDIDVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAK 134
+A E+ K Y + E+ +++T G E S+L +GDEVLIP PA+ Y
Sbjct: 74 QAASEFLLKKYGLSYAAEDEILVTVGVTEAISSVLLSILVAGDEVLIPAPAYPGYEPLIT 133
Query: 135 LAEAKPVRIPLREENNFMPDPDELLELVTK---KTRMIVINYPNNPTGATLDKEVAKAIA 191
LA V I R N+F+ P+ L + + + K + +++NYP NPTG T ++E K +A
Sbjct: 134 LAGGSLVEIDTRA-NDFVLTPEMLDQAIIEREGKVKAVILNYPANPTGVTYNREQIKDLA 192
Query: 192 DIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAP 251
++ + + +++++DE Y Y D H + ++APE TI+ N SK+ AMTGWR+G + A
Sbjct: 193 EVLKKHEVFVIADEVYSELNYTDQPHVSIAEYAPEQTIVLNGLSKSHAMTGWRIGLIFAA 252
Query: 252 SEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEM 311
E++ ++IK H Y++ + ++ Q A +EAL++ M+KEY +RR +++++ +
Sbjct: 253 RELVAQIIKTHQYLVTSASTQSQFAAIEALKNGAD--DALPMKKEYLKRRDYIIEKMSAL 310
Query: 312 PGIRVKEPKGAFYVFPSI-KDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYA 370
G ++ EP GAFY+F I D S KF+ ++ V +IPG AFG+ GEG+VR+SYA
Sbjct: 311 -GFKIIEPDGAFYIFAKIPADLEQDSFKFAVDFAKENAVAIIPGIAFGQYGEGFVRLSYA 369
Query: 371 TSREKLMEAMDRM 383
S + + +AM R+
Sbjct: 370 ASMDVIEQAMARL 382
>pir||D64385 aspartate transaminase (EC 2.6.1.1) - Methanococcus jannaschii
Length = 377
Score = 252 bits (636), Expect = 6e-66
Identities = 147/387 (37%), Positives = 231/387 (58%), Gaps = 24/387 (6%)
Query: 9 IAERVILIKRSKIRELFERASKMEN----VISLGIGEPDFDTPKNIKEACKRALDEGWTH 64
+++R++ + ++ ++ A K+E+ VI L IGEPDF+TPK I + ++L EG TH
Sbjct: 9 LSKRLLNFESFEVMDILALAQKLESEGKKVIHLEIGEPDFNTPKPIVDEGIKSLKEGKTH 68
Query: 65 YTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDP 124
YT + GI +LRE + E YK Y DI +N+IIT G+ G + A S+++ GDEVLI +P
Sbjct: 69 YTDSRGILELREKISELYKDKYKADIIPDNIIITGGSSLGLFFALSSIIDDGDEVLIQNP 128
Query: 125 AFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDK 184
+ Y + AKPV E+ L E ++ KT+ I+IN P+NP G +D+
Sbjct: 129 CYPCYKNFIRFLGAKPVFCDFTVES--------LEEALSDKTKAIIINSPSNPLGEVIDR 180
Query: 185 EVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAP--ENTILANSFSKTFAMTG 242
E I + A + YI+SDE Y +Y + K Y ++F E TIL N FSK +AMTG
Sbjct: 181 E----IYEFAYENIPYIISDEIYNGLVY-EGKCYSAIEFDENLEKTILINGFSKLYAMTG 235
Query: 243 WRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRK 302
WR+G+V++ EII+ ++KL + + + Q A ++A +E+ + + M KE++ RR+
Sbjct: 236 WRIGYVISNDEIIEAILKLQQNLFISAPTISQYAALKAF-EKETEREINSMIKEFDRRRR 294
Query: 303 LVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGE 362
LVLK +K+ G V P GA+YVFP+I + G +F+ LL++ V + PG FG G+
Sbjct: 295 LVLKYVKDF-GWEVNNPIGAYYVFPNIGEDG---REFAYKLLKEKFVALTPGIGFGSKGK 350
Query: 363 GYVRISYATSREKLMEAMDRMEKALSE 389
Y+RISYA S E + E ++R+++ L++
Sbjct: 351 NYIRISYANSYENIKEGLERIKEFLNK 377
>sp|Q58097|AAT2_METJA PROBABLE ASPARTATE AMINOTRANSFERASE 2 (TRANSAMINASE A) (ASPAT)
>gi|2826306|gb|AAB98679.1| (U67515) aspartate
aminotransferase (aspB2) [Methanococcus jannaschii]
Length = 370
Score = 252 bits (636), Expect = 6e-66
Identities = 147/387 (37%), Positives = 231/387 (58%), Gaps = 24/387 (6%)
Query: 9 IAERVILIKRSKIRELFERASKMEN----VISLGIGEPDFDTPKNIKEACKRALDEGWTH 64
+++R++ + ++ ++ A K+E+ VI L IGEPDF+TPK I + ++L EG TH
Sbjct: 2 LSKRLLNFESFEVMDILALAQKLESEGKKVIHLEIGEPDFNTPKPIVDEGIKSLKEGKTH 61
Query: 65 YTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDP 124
YT + GI +LRE + E YK Y DI +N+IIT G+ G + A S+++ GDEVLI +P
Sbjct: 62 YTDSRGILELREKISELYKDKYKADIIPDNIIITGGSSLGLFFALSSIIDDGDEVLIQNP 121
Query: 125 AFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDK 184
+ Y + AKPV E+ L E ++ KT+ I+IN P+NP G +D+
Sbjct: 122 CYPCYKNFIRFLGAKPVFCDFTVES--------LEEALSDKTKAIIINSPSNPLGEVIDR 173
Query: 185 EVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAP--ENTILANSFSKTFAMTG 242
E I + A + YI+SDE Y +Y + K Y ++F E TIL N FSK +AMTG
Sbjct: 174 E----IYEFAYENIPYIISDEIYNGLVY-EGKCYSAIEFDENLEKTILINGFSKLYAMTG 228
Query: 243 WRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRK 302
WR+G+V++ EII+ ++KL + + + Q A ++A +E+ + + M KE++ RR+
Sbjct: 229 WRIGYVISNDEIIEAILKLQQNLFISAPTISQYAALKAF-EKETEREINSMIKEFDRRRR 287
Query: 303 LVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGE 362
LVLK +K+ G V P GA+YVFP+I + G +F+ LL++ V + PG FG G+
Sbjct: 288 LVLKYVKDF-GWEVNNPIGAYYVFPNIGEDG---REFAYKLLKEKFVALTPGIGFGSKGK 343
Query: 363 GYVRISYATSREKLMEAMDRMEKALSE 389
Y+RISYA S E + E ++R+++ L++
Sbjct: 344 NYIRISYANSYENIKEGLERIKEFLNK 370
>gb|AAK41178.1| Aspartate aminotransferase (aspB-2) [Sulfolobus solfataricus]
Length = 402
Score = 250 bits (633), Expect = 1e-65
Identities = 144/389 (37%), Positives = 225/389 (57%), Gaps = 16/389 (4%)
Query: 11 ERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAG 70
E +L K +I E+ K++ +I GIG+PD T K I++A K ALD+G+T YT G
Sbjct: 17 ETTLLYK--EIARNVEKTKKIK-IIDFGIGQPDLPTFKRIRDAAKEALDQGFTFYTSAFG 73
Query: 71 IQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYV 130
I +LRE + +Y Y D+ E VI+T GA +L F + DEV++PDP+F SY
Sbjct: 74 IDELREKIAQYLNTRYGTDVKKEEVIVTPGAKPALFLVFILYINPSDEVILPDPSFYSYA 133
Query: 131 EDAKLAEAKPVRIPLR--EENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAK 188
E KL KP+ L+ E F D D+L ++K+T+MIV N P+NPTG K
Sbjct: 134 EVVKLLGGKPIYANLKWSREEGFSIDVDDLQSKISKRTKMIVFNNPHNPTGTLFSPNDVK 193
Query: 189 AIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAP--ENTILANSFSKTFAMTGWRLG 246
I DI++D I +LSDE Y++F+Y + K L+ + + I N FSKTF+MTGWRLG
Sbjct: 194 KIVDISRDNKIILLSDEIYDNFVY-EGKMRSTLEDSDWRDFLIYVNGFSKTFSMTGWRLG 252
Query: 247 FVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLK 306
++VA EII++M L A + SF+Q A V+A +++ V +M + +RR ++
Sbjct: 253 YIVAKREIIQKMGILAANVYTAPTSFVQKAAVKAF---DTFDEVNQMVSLFKKRRDVMYD 309
Query: 307 RLKEMPGIRVKEPKGAFYVFPSI----KDTGMSSEKFSEWLLEKARVVVIPGTAFG-KMG 361
L ++ G+ V +P GAFY+FP++ K +G + + L+E+ VV IPG F +G
Sbjct: 310 ELTKVKGVEVSKPNGAFYMFPNVSKILKTSGFDVKSLAIKLIEEKGVVTIPGEVFPLNIG 369
Query: 362 EGYVRISYATSREKLMEAMDRMEKALSEL 390
+ ++R+S+A + E + E + ++ + ++
Sbjct: 370 KEFLRLSFAVNEEVIKEGIQKIREFAEQM 398
>sp|P14909|AAT_SULSO ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|99262|pir||S07088 aspartate transaminase (EC
2.6.1.1) - Sulfolobus solfataricus
>gi|809765|emb|CAA34514.1| (X16505) aspartate
aminotransferase (AA 1-402) [Sulfolobus solfataricus]
>gi|226717|prf||1604198A Asp aminotransferase
[Sulfolobus solfataricus]
Length = 402
Score = 250 bits (633), Expect = 1e-65
Identities = 144/389 (37%), Positives = 225/389 (57%), Gaps = 16/389 (4%)
Query: 11 ERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAG 70
E +L K +I E+ K++ +I GIG+PD T K I++A K ALD+G+T YT G
Sbjct: 17 ETTLLYK--EIARNVEKTKKIK-IIDFGIGQPDLPTFKRIRDAAKEALDQGFTFYTSAFG 73
Query: 71 IQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYV 130
I +LRE + +Y Y D+ E VI+T GA +L F + DEV++PDP+F SY
Sbjct: 74 IDELREKIAQYLNTRYGTDVKKEEVIVTPGAKPALFLVFILYINPSDEVILPDPSFYSYA 133
Query: 131 EDAKLAEAKPVRIPLR--EENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAK 188
E KL KP+ L+ E F D D+L ++K+T+MIV N P+NPTG K
Sbjct: 134 EVVKLLGGKPIYANLKWSREEGFSIDVDDLQSKISKRTKMIVFNNPHNPTGTLFSPNDVK 193
Query: 189 AIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAP--ENTILANSFSKTFAMTGWRLG 246
I DI++D I +LSDE Y++F+Y + K L+ + + I N FSKTF+MTGWRLG
Sbjct: 194 KIVDISRDNKIILLSDEIYDNFVY-EGKMRSTLEDSDWRDFLIYVNGFSKTFSMTGWRLG 252
Query: 247 FVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLK 306
++VA EII++M L A + SF+Q A V+A +++ V +M + +RR ++
Sbjct: 253 YIVAKREIIQKMGILAANVYTAPTSFVQKAAVKAF---DTFDEVNQMVSLFKKRRDVMYD 309
Query: 307 RLKEMPGIRVKEPKGAFYVFPSI----KDTGMSSEKFSEWLLEKARVVVIPGTAFG-KMG 361
L ++ G+ V +P GAFY+FP++ K +G + + L+E+ VV IPG F +G
Sbjct: 310 ELTKVKGVEVSKPNGAFYMFPNVSKILKTSGFDVKSLAIKLIEEKGVVTIPGEVFPLNIG 369
Query: 362 EGYVRISYATSREKLMEAMDRMEKALSEL 390
+ ++R+S+A + E + E + ++ + ++
Sbjct: 370 KEFLRLSFAVNEEVIKEGIQKIREFAEQM 398
>pir||S45613 aspartate aminotransferase - Sulfolobus solfataricus
Length = 401
Score = 250 bits (633), Expect = 1e-65
Identities = 144/389 (37%), Positives = 225/389 (57%), Gaps = 16/389 (4%)
Query: 11 ERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAG 70
E +L K +I E+ K++ +I GIG+PD T K I++A K ALD+G+T YT G
Sbjct: 16 ETTLLYK--EIARNVEKTKKIK-IIDFGIGQPDLPTFKRIRDAAKEALDQGFTFYTSAFG 72
Query: 71 IQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYV 130
I +LRE + +Y Y D+ E VI+T GA +L F + DEV++PDP+F SY
Sbjct: 73 IDELREKIAQYLNTRYGTDVKKEEVIVTPGAKPALFLVFILYINPSDEVILPDPSFYSYA 132
Query: 131 EDAKLAEAKPVRIPLR--EENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAK 188
E KL KP+ L+ E F D D+L ++K+T+MIV N P+NPTG K
Sbjct: 133 EVVKLLGGKPIYANLKWSREEGFSIDVDDLQSKISKRTKMIVFNNPHNPTGTLFSPNDVK 192
Query: 189 AIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAP--ENTILANSFSKTFAMTGWRLG 246
I DI++D I +LSDE Y++F+Y + K L+ + + I N FSKTF+MTGWRLG
Sbjct: 193 KIVDISRDNKIILLSDEIYDNFVY-EGKMRSTLEDSDWRDFLIYVNGFSKTFSMTGWRLG 251
Query: 247 FVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLK 306
++VA EII++M L A + SF+Q A V+A +++ V +M + +RR ++
Sbjct: 252 YIVAKREIIQKMGILAANVYTAPTSFVQKAAVKAF---DTFDEVNQMVSLFKKRRDVMYD 308
Query: 307 RLKEMPGIRVKEPKGAFYVFPSI----KDTGMSSEKFSEWLLEKARVVVIPGTAFG-KMG 361
L ++ G+ V +P GAFY+FP++ K +G + + L+E+ VV IPG F +G
Sbjct: 309 ELTKVKGVEVSKPNGAFYMFPNVSKILKTSGFDVKSLAIKLIEEKGVVTIPGEVFPLNIG 368
Query: 362 EGYVRISYATSREKLMEAMDRMEKALSEL 390
+ ++R+S+A + E + E + ++ + ++
Sbjct: 369 KEFLRLSFAVNEEVIKEGIQKIREFAEQM 397
>sp|Q55128|AAT_SYNY3 ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|7447809|pir||S74343 probable aspartate transaminase
(EC 2.6.1.1) aspC sll0402 [similarity] - Synechocystis
sp. (strain PCC 6803) >gi|1001121|dbj|BAA10261.1|
(D64001) aspartate aminotransferase [Synechocystis sp.]
Length = 389
Score = 250 bits (631), Expect = 2e-65
Identities = 135/390 (34%), Positives = 226/390 (57%), Gaps = 12/390 (3%)
Query: 9 IAERVILIKRSKIRELFERASKME----NVISLGIGEPDFDTPKNIKEACKRALDEGWTH 64
+ +RV + S E+ +A M +V+S GEPDF TP +I EA K ALDEG T
Sbjct: 3 LTQRVSQVVPSITLEITAKAKAMRTEGIDVLSFTAGEPDFTTPPHIVEAAKLALDEGKTR 62
Query: 65 YTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDP 124
Y P AG LR+A+ + ++ ++ + N+++T G + +++E GDEV+IP P
Sbjct: 63 YGPAAGEPALRQAIAKKLREKNNLPYEAANILVTNGGKHSLFNLMLAMIEQGDEVIIPAP 122
Query: 125 AFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDK 184
++SY E +LAE PV + ++ P++L + +T K+++ V+N P+NPTGA
Sbjct: 123 YWLSYPEMVRLAEGTPVIVNTTAATDYKITPEQLRQAITSKSKLFVLNSPSNPTGAVYTP 182
Query: 185 EVAKAIADIAQDY-NIYILSDEPYEHFIYDDAKHYPMLKFAPE---NTILANSFSKTFAM 240
+A+A + +Y ++Y++SDE YE +YD +H + E TI++N F+K+++M
Sbjct: 183 AEIRALAAVILEYEDLYVVSDEIYERILYDGTEHLSIGAVNDEIFQRTIISNGFAKSYSM 242
Query: 241 TGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNER 300
TGWR+G++ +I+ + + NV +F Q + AL + ++ V+ M K + ER
Sbjct: 243 TGWRVGYLAGELPLIQACSTIQGHSTSNVCTFAQYGAIAALENPQT--CVETMVKAFTER 300
Query: 301 RKLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKM 360
R+++++ + ++ G+ PKGAFYVF I TG++S +FS LLE +V VIPG AFG
Sbjct: 301 RQVIVEGINQIAGLSCPNPKGAFYVFVDIAKTGLNSLEFSARLLESHQVAVIPGAAFG-- 358
Query: 361 GEGYVRISYATSREKLMEAMDRMEKALSEL 390
+ VR SYAT + + + + +E+ +S L
Sbjct: 359 ADDCVRFSYATDMDTIKQGLAELERFVSTL 388
>sp|Q02635|AATA_RHIME ASPARTATE AMINOTRANSFERASE A (TRANSAMINASE A) (ASPAT)
>gi|420886|pir||A47094 aspartate transaminase (EC
2.6.1.1) - Rhizobium meliloti >gi|152149|gb|AAA26245.1|
(L05064) aspartate aminotransferase [Sinorhizobium
meliloti]
Length = 400
Score = 246 bits (621), Expect = 4e-64
Identities = 149/396 (37%), Positives = 219/396 (54%), Gaps = 22/396 (5%)
Query: 8 FIAERVILIKRSKIRELFERASKME----NVISLGIGEPDFDTPKNIKEACKRALDEGWT 63
F+A+ + +K S + ++A +++ +VI LG GEPDFDTP NIK+A A+D G T
Sbjct: 3 FLADALSRVKPSATIAVSQKARELKAKGRDVIGLGAGEPDFDTPDNIKKAAIDAIDRGET 62
Query: 64 HYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPD 123
YTP +GI +LREA+ + +K+ ++D I+ G + + AF + L GDEV+IP
Sbjct: 63 KYTPVSGIPELREAIAKKFKRENNLDYTAAQTIVGTGGKQILFNAFMATLNPGDEVVIPA 122
Query: 124 PAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLD 183
P +VSY E L PV +P R+ENNF ++L +T KT+ V N P+NP+GA
Sbjct: 123 PYWVSYPEMVALCGGTPVFVPTRQENNFKLKAEDLDRAITPKTKWFVFNSPSNPSGAAYS 182
Query: 184 KEVAKAIADIAQDY-NIYILSDEPYEHFIYDDAKHYPMLKFAP---ENTILANSFSKTFA 239
E KA+ D+ + ++++L+D+ YEH Y D + ++ P E T+ N SK +A
Sbjct: 183 HEELKALTDVLMKHPHVWVLTDDMYEHLTYGDFRFATPVEVEPGLYERTLTMNGVSKAYA 242
Query: 240 MTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNE 299
MTGWR+G+ P +IK M + AS Q A VEAL + + + ++ +
Sbjct: 243 MTGWRIGYAAGPLHLIKAMDMIQGQQTSGAASIAQWAAVEALNGPQDF--IGRNKEIFQG 300
Query: 300 RRKLVLKRLKEMPGIRVKEPKGAFYVFPS----IKDTGMS------SEKFSEWLLEKARV 349
RR LV+ L + GI P+GAFYV+PS I T S E F LLE V
Sbjct: 301 RRDLVVSMLNQAKGISCPTPEGAFYVYPSCAGLIGKTAPSGKVIETDEDFVSELLETEGV 360
Query: 350 VVIPGTAFGKMGEGYVRISYATSREKLMEAMDRMEK 385
V+ G+AFG +G + RISYATS L EA R+++
Sbjct: 361 AVVHGSAFG-LGPNF-RISYATSEALLEEACRRIQR 394
>sp|Q9ZE56|AAT_RICPR ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|7447802|pir||B71718 probable aspartate transaminase
(EC 2.6.1.1) A RP091 [similarity] - Rickettsia
prowazekii >gi|3860660|emb|CAA14561.1| (AJ235270)
ASPARTATE AMINOTRANSFERASE A (aatA) [Rickettsia
prowazekii]
Length = 412
Score = 245 bits (619), Expect = 6e-64
Identities = 141/384 (36%), Positives = 218/384 (56%), Gaps = 18/384 (4%)
Query: 21 IRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVE 80
+++ E N+I+LG GEPDFDTP NIKE ++ +G+T YT GI L++A+
Sbjct: 33 VKKTLELKKAGVNIIALGAGEPDFDTPDNIKEVAITSIKDGFTKYTNVDGIPLLKQAIKN 92
Query: 81 YYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKP 140
+K+ ++D +++ +I++ G + Y F + L+ GDEV+IP P +VSY + L+ P
Sbjct: 93 KFKRENNIDYELDEIIVSTGGKQVIYNLFMASLDKGDEVIIPVPYWVSYPDMVALSTGTP 152
Query: 141 VRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDY-NI 199
V + ENNF + L +T KT+ ++IN P+NPTGA + + + IA + Y N+
Sbjct: 153 VFVNCGIENNFKLSVEALEHSITDKTKWLIINSPSNPTGAGYNCKELENIAKTLRKYPNV 212
Query: 200 YILSDEPYEHFIYDDAKHYPMLKFAP---ENTILANSFSKTFAMTGWRLGFVVAPSEIIK 256
I+SD+ YEH +DD K Y + + AP E N SK ++MTGWR+G+ +IK
Sbjct: 213 NIMSDDIYEHITFDDFKFYTLAQIAPDLKERIFTVNGVSKAYSMTGWRIGYGAGSKALIK 272
Query: 257 EMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRV 316
M + + N S Q+A +EAL + + +K + ++R L L L+E+
Sbjct: 273 AMTIIQSQSTSNPCSISQMAAIEALNGTQDY--IKSNALNFQKKRDLALSILEEVTYFEC 330
Query: 317 KEPKGAFYVFPSI-KDTG---------MSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVR 366
+P+GAFY+F K G +S FSE+LLE+A+V V+PG AFG +GY R
Sbjct: 331 YKPEGAFYLFVKCDKIFGTKTKSGRIIANSNNFSEYLLEEAKVAVVPGIAFGL--DGYFR 388
Query: 367 ISYATSREKLMEAMDRMEKALSEL 390
ISYATS ++L EA R++ A + L
Sbjct: 389 ISYATSMQELEEACIRIKHACNAL 412
>pir||B81347 aspartate transaminase (EC 2.6.1.1) Cj0762c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968208|emb|CAB73027.1| (AL139076) aspartate
aminotransferase [Campylobacter jejuni]
Length = 389
Score = 245 bits (618), Expect = 8e-64
Identities = 143/387 (36%), Positives = 217/387 (55%), Gaps = 10/387 (2%)
Query: 1 MRQKRKYFIAERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDE 60
M KR + E + L + EL +K E++IS GEPDFDTP+ IK A A+++
Sbjct: 1 MLTKRSQVLEESITLAITALANEL---KAKGEDIISFSAGEPDFDTPQTIKNAAISAIEK 57
Query: 61 GWTHYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVL 120
G YT AGI ++ +A+ +KK ++D + +I GA + E L+E DEV+
Sbjct: 58 GCGKYTAVAGIPEVLKAIQTKFKKDNNLDYETNEIITNVGAKHSLFECIECLVEKDDEVI 117
Query: 121 IPDPAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGA 180
IP P +VSY E K A KPV I EEN F ++L + +T KT+++++N P+NP G+
Sbjct: 118 IPSPYWVSYPEMVKFAGGKPVFIEGLEENGFKITAEQLKKAITAKTKVLMLNSPSNPVGS 177
Query: 181 TLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDD---AKHYPMLKFAPENTILANSFSKT 237
KE IA + + I +LSDE YE YD + K A + T+ N SK
Sbjct: 178 IYSKEELTQIAKVLEGTQITVLSDEMYEKLRYDGFDFVAFASVSKDALKRTVTINGLSKC 237
Query: 238 FAMTGWRLGFVVAPSE-IIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKE 296
AM GWR G++ + ++ +I + +L N+ S Q A + AL E K +++MR+
Sbjct: 238 GAMPGWRFGYMASKNKALISAVKRLQGQSTSNICSITQHAAIPALNGECD-KDIEKMRQA 296
Query: 297 YNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTA 356
+ +RR L L LK++P I V +P+GAFY+F +I+ S KF + LLE+ +V V+PG
Sbjct: 297 FEKRRNLALDILKQIPNISVYKPEGAFYLFVNIQKIEKDSMKFCQKLLEQEKVAVVPGVG 356
Query: 357 FGKMGEGYVRISYATSREKLMEAMDRM 383
FG +GY R+SYATS E + + ++R+
Sbjct: 357 FGM--DGYFRLSYATSDELIKKGLERI 381
>sp|Q60013|AAT_STRVG ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|7447833|pir||T11786 aspartate transaminase (EC
2.6.1.1) - Streptomyces virginiae
>gi|1217910|dbj|BAA09299.1| (D50624) aspartate
aminotransferase [Streptomyces virginiae]
Length = 397
Score = 242 bits (610), Expect = 7e-63
Identities = 130/369 (35%), Positives = 212/369 (57%), Gaps = 17/369 (4%)
Query: 34 VISLGIGEPDFDTPKNIKEACKRALDEGWTH-YTPNAGIQQLREAVVEYYKKFYDVDIDV 92
VI G GEPDF TP I EA A H YTP G+ +L+ A+ + +++
Sbjct: 30 VIGFGAGEPDFPTPDYIVEAAVEACRNPKYHRYTPAGGLPELKAAIAAKTLRDSGYEVEA 89
Query: 93 ENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENNFM 152
V++T G + Y AF ++L+ GDEV++P P + +Y E +LA PV + E +
Sbjct: 90 SQVLVTNGGKQAIYEAFAAILDPGDEVIVPAPYWTTYPESIRLAGGVPVDVVADETTGYR 149
Query: 153 PDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHFIY 212
++L T++T++++ P+NPTG+ + AKAI + A ++ +++L+DE YEH +Y
Sbjct: 150 VSVEQLEAARTERTKVVLFVSPSNPTGSVYSEADAKAIGEWAAEHGLWVLTDEIYEHLVY 209
Query: 213 DDAKHYPMLKFAP---ENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNV 269
+AK + P + I+ N +KT+AMTGWR+G+V+AP ++IK L ++ NV
Sbjct: 210 GEAKFTSLPVLVPALRDKCIIVNGVAKTYAMTGWRVGWVIAPQDVIKAATNLQSHATSNV 269
Query: 270 ASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSI 329
++ QVA + A+ + AV EMRK ++ RR+ ++K L E+ G+ P+GAFY +PS+
Sbjct: 270 SNVAQVAALAAVSG--NLDAVAEMRKAFDRRRQTMVKMLNEIDGVFCPTPEGAFYAYPSV 327
Query: 330 KD---------TGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAM 380
K+ SS + + +L++ V V+PG AFG GY+R+SYA E L+E +
Sbjct: 328 KELLGKEIRGKRPQSSVELAALILDEVEVAVVPGEAFGT--PGYLRLSYALGDEDLVEGV 385
Query: 381 DRMEKALSE 389
R++K L+E
Sbjct: 386 SRIQKLLAE 394
>gi|11499943 aspartate aminotransferase (aspB-1) [Archaeoglobus fulgidus]
>gi|7447820|pir||F69545 probable aspartate transaminase
(EC 2.6.1.1) aspB1 AF2366 [similarity] - Archaeoglobus
fulgidus >gi|2650722|gb|AAB91291.1| (AE001112) aspartate
aminotransferase (aspB-1) [Archaeoglobus fulgidus]
Length = 373
Score = 242 bits (610), Expect = 7e-63
Identities = 146/377 (38%), Positives = 214/377 (56%), Gaps = 22/377 (5%)
Query: 10 AERVILIKRSKIRELFE---RASKM-ENVISLGIGEPDFDTPKNIKEACKRALDEGWTHY 65
A R+ I S IR +FE RA K +ISL IGEPDFDTP+ + E RA++ G+THY
Sbjct: 4 AARLSQISTSMIRRMFEIVERAKKEGREIISLTIGEPDFDTPQEVIERACRAMNAGFTHY 63
Query: 66 TPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPA 125
T N G+++LR A+ E Y +D NV++TAG E A + +E G +V+IP P
Sbjct: 64 TSNFGLEELRSAIAERY------GVDSSNVMVTAGGSEALLNASLAFIEEGSKVVIPSPN 117
Query: 126 FVSYVEDAKLAEAKPVRIPLREENN-FMPDPDELLELVTKKTRMIVINYPNNPTGATLDK 184
F+SY AK+ + V+ LR NN F+PD ++L E++ + +I +NYPNNPTGA +D+
Sbjct: 118 FLSYFTYAKMCGGQIVQ--LRTHNNGFLPDVEKLNEIIDRNVSVIFLNYPNNPTGAVIDE 175
Query: 185 EVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWR 244
+ A+A+ +IA D ++SDE Y+ YD P EN + N FSK+ +MTGWR
Sbjct: 176 KDARAVVEIAADNKAIVVSDEIYDQIYYDVK---PTSLAGYENVVCVNGFSKSLSMTGWR 232
Query: 245 LGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLV 304
+GF +A +++ M+K+H +F Q A E + V M KE+ +RR +
Sbjct: 233 IGFTIADEKLLDPMLKVHQVNGVCAPAFAQKAVAEVMAERLFDSIVSRMVKEFRQRRDYL 292
Query: 305 LKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGY 364
L ++ V +P+GAFY+F ++ M +++E L+ V V PG FG E Y
Sbjct: 293 YSELSKI--YDVVKPEGAFYMFVNVNQDCM---EYAENLINLG-VAVTPGLPFGDGNETY 346
Query: 365 VRISYATSREKLMEAMD 381
VRISYA S E L +A +
Sbjct: 347 VRISYANSLENLKKAAE 363
>gb|AAG19034.1| (AE005003) aspartate aminotransferase; AspB1 [Halobacterium sp.
NRC-1]
Length = 373
Score = 238 bits (601), Expect = 8e-62
Identities = 143/380 (37%), Positives = 210/380 (54%), Gaps = 19/380 (5%)
Query: 10 AERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTH-YTPN 68
++RV + S IR +FE A E+ I+LG+G+PDF TP + ++A A++ G YT N
Sbjct: 5 SDRVAQVSISGIRAVFEAAG--EDAINLGLGQPDFPTPDHARQAAVDAIESGAADGYTSN 62
Query: 69 AGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVS 128
G L +A+VE + + VD+ VI TAG E +LA E+ ++ GDEVL PDP FVS
Sbjct: 63 RGTAALVDAIVEKHARDQGVDVAPAGVIATAGGSEALHLAMEAHVDPGDEVLFPDPGFVS 122
Query: 129 YVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAK 188
Y ++A PV +PLR++ P+ E + +T T V+N P NPTGA +
Sbjct: 123 YDALTRMAGGNPVGLPLRDDLTLAPETVE--DHITDDTAAFVVNSPANPTGAVQSPADMR 180
Query: 189 AIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFV 248
A A IA ++++ +SDE YEH +++ PM +N ++ N+ SKT++MTGWRLG+V
Sbjct: 181 AFARIADEHDVLCISDEVYEHIVFEGEHRSPMEFADTDNVVVVNACSKTYSMTGWRLGWV 240
Query: 249 VAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRL 308
A + M+++H Y+ ++ Q A AL + V EM + RR ++L L
Sbjct: 241 AASERRAERMLRVHQYVQACASAPAQYAAEAALSGPQG--VVDEMVAAFEARRDVLLDGL 298
Query: 309 KEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLE--KARVVVIPGTAFGKMGEGYVR 366
+ M G+ V P GAFY P++ D W+ E VVV+PG+AFG G G R
Sbjct: 299 EAM-GLDVPTPGGAFYAMPTVPD---------GWIDEVVDRGVVVVPGSAFGDHGAGTAR 348
Query: 367 ISYATSREKLMEAMDRMEKA 386
ISYAT L +A+D M A
Sbjct: 349 ISYATDMATLRDAIDVMRAA 368
>gb|AAG19132.1| (AE005011) aspartate aminotransferase; AspB2 [Halobacterium sp.
NRC-1]
Length = 380
Score = 237 bits (598), Expect = 2e-61
Identities = 139/379 (36%), Positives = 221/379 (57%), Gaps = 17/379 (4%)
Query: 12 RVILIKRSKIRELFERASKME----NVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTP 67
RV ++ S + AS++E +V+ L +GEPDFDTP++I +A K A+D G T Y P
Sbjct: 6 RVTSVEPSATLAVSTLASELEADGVDVVDLSVGEPDFDTPESIVDAGKAAMDAGHTGYAP 65
Query: 68 NAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
+ G+ +LR+A+ E + +D + NVI+T GA + Y F+++++ GDEV + DPA+V
Sbjct: 66 SNGVPELRDAIAEKLQGD-GLDYEAGNVIVTPGAKQALYETFQAVVDEGDEVALLDPAWV 124
Query: 128 SYVEDAKLAEAKPVRIPLREEN-NFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEV 186
SY AKLA + R+ L + P D+L + V+ T ++V+N P+NPTGA +
Sbjct: 125 SYEAMAKLAGGELNRVDLAPHDFQLEPALDDLADAVSDDTELLVVNSPSNPTGAVYSRAA 184
Query: 187 AKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPM--LKFAPENTILANSFSKTFAMTGWR 244
+ + D+A D++I ++SDE Y+ Y A H + L E T+ N FSK ++MTGWR
Sbjct: 185 MEGVRDLAVDHDITVISDEIYQRVNYGPA-HVSLAGLDGMFERTVTINGFSKAYSMTGWR 243
Query: 245 LGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLV 304
LG++ P ++ + K+ ++ + + A+FIQ AGVEA+R + A+ EM + RR L+
Sbjct: 244 LGYLAGPEALVDQAGKVQSHSVSSAANFIQRAGVEAIRHTDD--AIDEMVAAFESRRDLL 301
Query: 305 LKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGY 364
+ E G V P GAFY+ + D + + + L+ A V +PG+AFG GY
Sbjct: 302 VDLFAE-HGTDVSTPDGAFYLMLPVAD---DDQAWCQDALKDAHVATVPGSAFG--APGY 355
Query: 365 VRISYATSREKLMEAMDRM 383
R+SYA S ++L A+DR+
Sbjct: 356 ARLSYAASTDRLEAAVDRL 374
>emb|CAB77419.1| (AL160431) aspartate aminotransferase [Streptomyces coelicolor
A3(2)]
Length = 408
Score = 236 bits (597), Expect = 2e-61
Identities = 128/369 (34%), Positives = 207/369 (55%), Gaps = 17/369 (4%)
Query: 34 VISLGIGEPDFDTPKNIKEACKRALDEGWTH-YTPNAGIQQLREAVVEYYKKFYDVDIDV 92
VI G GEPDF TP I EA A H YTP G+ +L+ A+ + ++D
Sbjct: 41 VIGFGAGEPDFPTPDYIVEAAVEACKNPKFHRYTPAGGLPELKAAIAAKTLRDSGYEVDP 100
Query: 93 ENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENNFM 152
+++T G + Y AF ++L+ GDEV++P P + +Y E +LA PV + E +
Sbjct: 101 SQILVTNGGKQAIYEAFAAILDPGDEVIVPAPYWTTYPESIRLAGGVPVEVVADETTGYR 160
Query: 153 PDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHFIY 212
++L T+KT++++ P+NPTGA + +AI A ++ +++L+DE YEH +Y
Sbjct: 161 VTVEQLEAARTEKTKVVLFVSPSNPTGAVYGEAETEAIGRWAVEHGLWVLTDEIYEHLVY 220
Query: 213 DDAKHYPMLKFAPE---NTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNV 269
DA + PE I+ N +KT+AMTGWR+G+V+ P +++K L ++ NV
Sbjct: 221 GDAVSVSLPALLPELRDKCIVVNGVAKTYAMTGWRVGWVIGPKDVVKAATNLQSHATSNV 280
Query: 270 ASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSI 329
A+ Q A + A+ + AV +MR+ ++ RR+ +++ L E+ G+ EP+GAFY +PS+
Sbjct: 281 ANVSQAAALAAVSG--NLDAVAKMREAFDRRRQTIVRMLNEIDGVLCPEPEGAFYAYPSV 338
Query: 330 K---------DTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAM 380
K S + + +LE+A V V+PG AFG GY+R+SYA E L+E +
Sbjct: 339 KALLGKEIRGKRPQDSVELAALILEEAEVAVVPGEAFGT--PGYLRLSYALGDEDLVEGV 396
Query: 381 DRMEKALSE 389
R++K L+E
Sbjct: 397 SRIQKLLAE 405
>pir||B72275 probable aspartate transaminase (EC 2.6.1.1) TM1255 [similarity] -
Thermotoga maritima (strain MSB8)
>gi|4981811|gb|AAD36330.1|AE001781_1 (AE001781)
aspartate aminotransferase [Thermotoga maritima]
Length = 377
Score = 235 bits (593), Expect = 7e-61
Identities = 137/386 (35%), Positives = 225/386 (57%), Gaps = 18/386 (4%)
Query: 9 IAERVILIKRSKIRELFERAS----KMENVISLGIGEPDFDTPKNIKEACKRALDEGWTH 64
++ R+ I SK EL +A K E+VI+L GEPDF TP+ + E R L +G
Sbjct: 2 VSRRISEIPISKTMELDAKAKALIKKGEDVINLTAGEPDFPTPEPVVEEAVRFLQKGEVK 61
Query: 65 YTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDP 124
YT GI +LRE + + + Y DI + V++T GA + + AF +LL+ GDEV++ P
Sbjct: 62 YTDPRGIYELREGIAKRIGERYKKDISPDQVVVTNGAKQALFNAFMALLDPGDEVIVFSP 121
Query: 125 AFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDK 184
+VSY+ LA + NF P +E+ L+ KT+ ++IN PNNPTG +
Sbjct: 122 VWVSYIPQIILAGGTVNVVETFMSKNFQPSLEEVEGLLVGKTKAVLINSPNNPTGVVYRR 181
Query: 185 EVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAP--ENTILANSFSKTFAMTG 242
E + + +A+ N YI+SDE Y+ +Y D + +L + + + N FSK+ +MTG
Sbjct: 182 EFLEGLVRLAKKRNFYIISDEVYDSLVYTD-EFTSILDVSEGFDRIVYINGFSKSHSMTG 240
Query: 243 WRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRK 302
WR+G++++ ++ + K+ ++ + + Q A ++AL + S+ M + + ER+
Sbjct: 241 WRVGYLISSEKVATAVSKIQSHTTSCINTVAQYAALKALEVDNSY-----MVQTFKERKN 295
Query: 303 LVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGE 362
V++RLK+M G++ EP+GAFY+F ++ + KF E LLE+ +V ++PG+AF K
Sbjct: 296 FVVERLKKM-GVKFVEPEGAFYLFFKVRGDDV---KFCERLLEEKKVALVPGSAFLK--P 349
Query: 363 GYVRISYATSREKLMEAMDRMEKALS 388
G+VR+S+ATS E+L EA+DR+E L+
Sbjct: 350 GFVRLSFATSIERLTEALDRIEDFLN 375
>sp|O86459|AAT_RHILP ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|3559982|emb|CAA07198.1| (AJ006709) putative
aspartate aminotransferase [Rhizobium leguminosarum]
Length = 400
Score = 233 bits (589), Expect = 2e-60
Identities = 143/396 (36%), Positives = 217/396 (54%), Gaps = 22/396 (5%)
Query: 8 FIAERVILIKRSKIRELFERASKME----NVISLGIGEPDFDTPKNIKEACKRALDEGWT 63
F+A+ + +K S + ++A +++ +VI LG GEPDFDTP NIK+A A++ G T
Sbjct: 3 FLADALSRVKPSATIAVSQKARELKAKGRDVIGLGAGEPDFDTPDNIKKAAIDAINRGET 62
Query: 64 HYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPD 123
YTP +GI +LR+A+ +K+ +D E I+ G + + AF + L GDEV IP
Sbjct: 63 KYTPVSGIPELRKAIAAKFKRENGLDYSWEQTIVGTGGKQILFNAFMATLNPGDEVSIPA 122
Query: 124 PAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLD 183
P +VSY E L + +E+NF +L + +T KT+ + N P+NPTGA
Sbjct: 123 PYWVSYPEMVALCGGTRFFVSATQEHNFKLQAADLEKAITPKTKWFIFNSPSNPTGAAYT 182
Query: 184 KEVAKAIADI-AQDYNIYILSDEPYEHFIYDDAKHYPMLKFAP---ENTILANSFSKTFA 239
+ KA+ D+ ++ +++L+D+ YEH Y D K ++ P + T+ N SK +A
Sbjct: 183 HDELKALTDVLMKNPQVWVLTDDMYEHLTYGDFKFVTPVEVEPQLYDRTLTMNGVSKAYA 242
Query: 240 MTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNE 299
MTGWR+G+ P ++IK M + S Q A VEAL + + + E +K +
Sbjct: 243 MTGWRIGYAAGPIQLIKAMDMIQGQQTSGATSIAQWAAVEALNGTQDF--IPENKKIFEG 300
Query: 300 RRKLVLKRLKEMPGIRVKEPKGAFYVFPSIK-------DTGM---SSEKFSEWLLEKARV 349
RR LV+ L + GI P+GAFYV+PS K +G + E F LLE V
Sbjct: 301 RRDLVVSMLNQAKGIVCPVPEGAFYVYPSCKGLIGKTAPSGKVIETDEDFVSELLESEGV 360
Query: 350 VVIPGTAFGKMGEGYVRISYATSREKLMEAMDRMEK 385
V+ G+AFG +G + RISYATS E+L EA R+++
Sbjct: 361 AVVHGSAFG-LGPNF-RISYATSEEQLEEACRRIQR 394
>gb|AAF12702.1|AF035157_1 (AF035157) aspartate aminotransferase [Lactococcus lactis]
Length = 393
Score = 233 bits (587), Expect = 4e-60
Identities = 132/366 (36%), Positives = 209/366 (57%), Gaps = 13/366 (3%)
Query: 33 NVISLGIGEPDFDTPKNIKEACKRALDEGW-THYTPNAGIQQLREAVVEYYKKFYDVDID 91
++I L +G+PDF TPK I +A A++ G + YT G+ +L++AV Y+ +FY +I
Sbjct: 32 DIIDLTLGQPDFPTPKKIGQAAIEAINNGQASFYTQAGGLPELKKAVQHYWTRFYAYEIQ 91
Query: 92 VENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENNF 151
++ITAGA Y F + ++ DEV+IP P +VSYV+ K+A PV + ++ENNF
Sbjct: 92 TNEILITAGAKFALYAYFMATVDPLDEVIIPAPYWVSYVDQVKMAGGNPVIVEAKQENNF 151
Query: 152 MPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHFI 211
++L + T KT+++++N P+NPTG KE AI + A +++ IL+D+ Y +
Sbjct: 152 KVTVEQLEKARTSKTKILLLNSPSNPTGMIYSKEELTAIGEWAVAHDLLILADDIYHRLV 211
Query: 212 YDDAKHYPMLKFAPE---NTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGN 268
Y+ A+ + + E T + N SKTFAMTGWR+G V EII M K+ + N
Sbjct: 212 YNGAEFTAISSLSDEIRNRTTVINGVSKTFAMTGWRIGLAVGDPEIIAAMTKIASQTTSN 271
Query: 269 VASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPS 328
+ Q A +EA EE+ K+ ++M + ER + +L E+PG + +P GAFY+FP
Sbjct: 272 PTAVAQYAAIEAF--EENDKSFEKMHAAFEERLNKIYLQLSEVPGFELVKPNGAFYLFPK 329
Query: 329 I-KDTGMSS----EKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAMDRM 383
+ K M F+ +LE+A V ++ G FG VR+SYATS E L A+ R+
Sbjct: 330 VTKAMAMKGYTDVTDFTTAILEEAGVALVTGAGFGSPEN--VRLSYATSLETLEAAVTRL 387
Query: 384 EKALSE 389
+ +++
Sbjct: 388 KDWMND 393
>pir||B70325 probable transaminase (EC 2.6.1.-) aspC4 [similarity] - Aquifex
aeolicus >gi|2982964|gb|AAC06578.1| (AE000681)
aminotransferase (AspC family) [Aquifex aeolicus]
Length = 387
Score = 229 bits (578), Expect = 4e-59
Identities = 136/367 (37%), Positives = 209/367 (56%), Gaps = 8/367 (2%)
Query: 22 RELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPN-AGIQQLREAVVE 80
R+ E+ + +VI LG+G+PD TPK I EA K+AL+ H P+ G + R+AV +
Sbjct: 21 RKKQEKIEQGVDVIDLGVGDPDMPTPKPIVEAAKKALENPENHKYPSYVGKYEFRKAVAD 80
Query: 81 YYKKFYDVDIDVENVIITA-GAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAK 139
+YK+ +DVD+D +IT G+ EG + + GD VL PDPA+ Y A A
Sbjct: 81 WYKRRFDVDLDPNTEVITLIGSKEGIAHFPLAFVNPGDIVLCPDPAYPVYRIGAIFAGGT 140
Query: 140 PVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNI 199
P +PL+EENNF+PD D + E V KK ++I INYPNNPT A E K + D A++YN+
Sbjct: 141 PYTVPLKEENNFLPDLDSIPEDVAKKAKIIWINYPNNPTSAPPTLEFYKKLVDWAKEYNV 200
Query: 200 YILSDEPYEHFIYDDAKHYPMLKF--APENTILANSFSKTFAMTGWRLGFVVAPSEIIKE 257
I SD Y K +L+ A + I +S SKT+ MTGWR+G V E++
Sbjct: 201 IIASDNAYSEIYTGQEKPPSILQVPGAKDVAIEFHSLSKTYNMTGWRIGMAVGNKELVAG 260
Query: 258 MIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVK 317
+ K+ + +Q AG+ AL E + V+++R Y ER+K++ + L+++ G+ +
Sbjct: 261 LGKVKTNVDSGQFGAVQDAGIVALNLPE--EEVEKIRDVYRERKKIMTEALEKI-GLEIY 317
Query: 318 EPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLM 377
FY++ + + G +S +F L+++A +V PG FG+ GEGY RIS E+L+
Sbjct: 318 RSDYTFYLWIKVPE-GYTSAEFVGRLIDEAGIVCTPGNGFGEYGEGYFRISLTVPTERLL 376
Query: 378 EAMDRME 384
EA +R++
Sbjct: 377 EAAERIK 383
>pir||F83024 aspartate transaminase PA4976 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9951259|gb|AAG08361.1|AE004910_8
(AE004910) aspartate transaminase [Pseudomonas
aeruginosa]
Length = 393
Score = 228 bits (576), Expect = 7e-59
Identities = 124/365 (33%), Positives = 202/365 (54%), Gaps = 3/365 (0%)
Query: 27 RASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFY 86
R + E ++ L +G+PDFDTP I +A +L G THY G + LR+ + E +++
Sbjct: 27 RVEQGEEILLLSVGDPDFDTPAPIVQAAIDSLLAGNTHYADVRGKRALRQRIAERHRRRS 86
Query: 87 DVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLR 146
+D E V++ AGA Y + LL GDEV++ +P +V+Y A+ V +P+R
Sbjct: 87 GQAVDAEQVVVLAGAQCALYAVVQCLLNPGDEVIVAEPMYVTYEAVFGACGARVVPVPVR 146
Query: 147 EENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEP 206
EN F +E+ L+T +TR + +N P+NP+GA+L + +A+A++ ++++++SDE
Sbjct: 147 SENGFRVQAEEVAALITPRTRAMALNSPHNPSGASLPRATWEALAELCMAHDLWMISDEV 206
Query: 207 YEHFIYDDAKHYP-MLKFAPENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYI 265
Y ++D P L + T NS SK+ AMTGWR+G+VV P+ + + L +
Sbjct: 207 YSELLFDGEHVSPASLPGMADRTATLNSLSKSHAMTGWRVGWVVGPAALCAHLENLALCM 266
Query: 266 IGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYV 325
+ FIQ A AL E ++ MR+ Y RR LV++ L + PG+R P G +V
Sbjct: 267 LYGSPEFIQDAACTAL--EAPLPELEAMREAYRRRRDLVIECLADSPGLRPLRPDGGMFV 324
Query: 326 FPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAMDRMEK 385
I+ TG+S++ F++ LL++ V V+ G AFG G++R+ E L EA R+
Sbjct: 325 MVDIRPTGLSAQAFADRLLDRHGVSVLAGEAFGPSAAGHIRLGLVLGAEPLREACRRIAL 384
Query: 386 ALSEL 390
+EL
Sbjct: 385 CAAEL 389
>pir||D71003 probable transaminase (EC 2.6.1.-) PH1322 [similarity] - Pyrococcus
horikoshii >gi|3257745|dbj|BAA30428.1| (AP000006) 401aa
long hypothetical aspartate aminotransferase [Pyrococcus
horikoshii]
Length = 401
Score = 227 bits (573), Expect = 2e-58
Identities = 142/380 (37%), Positives = 212/380 (55%), Gaps = 20/380 (5%)
Query: 22 RELFERASKMENVISLGIGEP---DFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAV 78
REL ++ K VI L IG+P DF P+++KEA RA+ EG +Y + G+ +LREA+
Sbjct: 26 RELEKKGIK---VIRLNIGDPVKFDFQPPEHMKEAYCRAIQEGHNYYGDSEGLIELREAI 82
Query: 79 VEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEA 138
V+ K+ VDI ++V +TA E L F +LL+ GDE+LIP P++ Y K
Sbjct: 83 VKREKEKNGVDITPDDVRVTAAVTEALQLIFGALLDPGDEILIPGPSYPPYTGLVKFYGG 142
Query: 139 KPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYN 198
KPV EE + PD D+L + ++++T+ I + PNNPTGA DK+ + I ++A +++
Sbjct: 143 KPVEYRTIEEEGWQPDIDDLRKKISERTKAIAVINPNNPTGALYDKKTIEEIINVAGEHD 202
Query: 199 IYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFV--VAP----S 252
+ +LSDE Y+ Y+ P I+ N SK + TGWRLG++ V P S
Sbjct: 203 LVVLSDEIYDLMTYEGKHISPGSLTKDVPVIVMNGLSKVYFATGWRLGYMYFVDPEGKLS 262
Query: 253 EIIKEMIKLHAYII--GNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKE 310
E+ + + KL I F +AG+ S +KE K+ ERR + KRL E
Sbjct: 263 EVREAIDKLARIRICPNTPGQFAAIAGLTG-----SMDYLKEYMKKLKERRDFIYKRLNE 317
Query: 311 MPGIRVKEPKGAFYVFPSIKDTGMSSEK-FSEWLLEKARVVVIPGTAFGKMGEGYVRISY 369
+PGI +P+GAFY+FP I++ S+K F +L A V+ + G+ FG+ G+G+ RI +
Sbjct: 318 IPGISTTKPQGAFYIFPRIEEGPWKSDKEFVLDVLHNAHVLFVHGSGFGEYGKGHFRIVF 377
Query: 370 ATSREKLMEAMDRMEKALSE 389
E L EAMDR EK + E
Sbjct: 378 LPPIEILEEAMDRFEKFMRE 397
>pir||H71909 probable aspartate transaminase (EC 2.6.1.1) aspB [similarity] -
Helicobacter pylori (strain J99)
>gi|4155168|gb|AAD06196.1| (AE001493) ASPARTATE
AMINOTRANSFERASE [Helicobacter pylori J99]
Length = 390
Score = 224 bits (565), Expect = 1e-57
Identities = 124/364 (34%), Positives = 214/364 (58%), Gaps = 7/364 (1%)
Query: 26 ERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKF 85
E S+ ++++S GEPDFDTP+ IK+A +AL++G+T YTP AGI +L +A+ KK
Sbjct: 24 ELKSQGKDILSFSAGEPDFDTPQAIKDAAIKALNDGFTKYTPVAGIPELLKAIAFKLKKE 83
Query: 86 YDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPL 145
++D + ++++ GA + + A ++L+ GDEV+IP P +V+Y E K + I
Sbjct: 84 NNLDYEPSEILVSNGAKQSLFNAIQALIGEGDEVVIPVPFWVTYPELVKYSGGVSQFIQT 143
Query: 146 REENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDE 205
E+++F P +L + ++ KT+M+++ P+NPTG K +A+ ++ +D +++LSDE
Sbjct: 144 DEKSHFKITPKQLKDALSPKTKMLILTTPSNPTGMLYSKAELEALGEVLKDTKVWVLSDE 203
Query: 206 PYEHFIY--DDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVA-PSEIIKEMIKLH 262
YE +Y + + + + TI N SK+ AMTGWR+G+ + +++K M L
Sbjct: 204 IYEKLVYKGEFVSCAAVSEEMKKRTITINGLSKSVAMTGWRMGYAASKDKKLVKLMSNLQ 263
Query: 263 AYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGA 322
+ N+ S Q+A + AL K ++ MR+ + +R L ++ + G+ +P GA
Sbjct: 264 SQCTSNINSITQMASIVALEGLVD-KEIETMRQAFEKRCHLAHAKINAIEGLNALKPDGA 322
Query: 323 FYVFPSIKD-TGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAMD 381
FY+F +I G S +F LLEK V ++PG AFG EGYVR+S+A S E++ + ++
Sbjct: 323 FYLFINIGSLCGGDSMRFCHELLEKEGVALVPGKAFGL--EGYVRLSFACSEEQIEKGIE 380
Query: 382 RMEK 385
R+ +
Sbjct: 381 RIAR 384
>pir||H64603 probable aspartate transaminase (EC 2.6.1.1) P0672 [similarity] -
Helicobacter pylori (strain 26695)
>gi|2313794|gb|AAD07733.1| (AE000580) solute-binding
signature and mitochondrial signature protein (aspB)
[Helicobacter pylori 26695]
Length = 390
Score = 222 bits (559), Expect = 7e-57
Identities = 123/364 (33%), Positives = 212/364 (57%), Gaps = 7/364 (1%)
Query: 26 ERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKF 85
E S+ ++++S GEPDFDTP+ IK+A +AL++G+T YTP AGI +L +A+ KK
Sbjct: 24 ELKSQGKDILSFSAGEPDFDTPQAIKDAAIKALNDGFTKYTPVAGIPELLKAIAFKLKKE 83
Query: 86 YDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPL 145
++D + ++++ GA + + A ++L+E GDEV+IP P +V+Y E K + I
Sbjct: 84 NNLDYEPNEILVSNGAKQSLFNAIQALIEEGDEVIIPVPFWVTYPELVKYSGGVSQFIQT 143
Query: 146 REENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDE 205
E+++F P +L + ++ KT+M+++ P+NPTG K + + ++ +D +++LSDE
Sbjct: 144 DEKSHFKITPKQLKDALSPKTKMLILTTPSNPTGMLYSKAELEVLGEVLKDTKVWVLSDE 203
Query: 206 PYEHFIY--DDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVA-PSEIIKEMIKLH 262
YE +Y + + + + TI + SK+ AMTGWR+G+ + +++K M L
Sbjct: 204 IYEKLVYKGEFVSCAAVSEEMKKRTITISGLSKSVAMTGWRMGYAASKDKKLVKLMNNLQ 263
Query: 263 AYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGA 322
+ N+ S Q+A + AL K ++ MR+ + R L ++ + G+ +P GA
Sbjct: 264 SQCTSNINSITQMASIVALEGLVD-KEIETMRQAFERRCDLAHAKINAIGGLNALKPDGA 322
Query: 323 FYVFPSIKD-TGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAMD 381
FY+F I G S +F LLEK V ++PG AFG EGYVR+S+A S E++ + ++
Sbjct: 323 FYLFIHIGSLCGGDSMRFCHELLEKEGVALVPGKAFGL--EGYVRLSFACSEEQIEKGIE 380
Query: 382 RMEK 385
R+ +
Sbjct: 381 RIAR 384
>pir||G70010 probable aspartate transaminase (EC 2.6.1.1) yugH [similarity] -
Bacillus subtilis >gi|1934791|emb|CAB07920.1| (Z93934)
unknown [Bacillus subtilis] >gi|2635636|emb|CAB15129.1|
(Z99120) similar to aspartate aminotransferase [Bacillus
subtilis]
Length = 357
Score = 221 bits (558), Expect = 9e-57
Identities = 126/348 (36%), Positives = 195/348 (55%), Gaps = 6/348 (1%)
Query: 8 FIAERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTP 67
++++ V IK S IR+ F+ A+ ME VISLG+GEPDF T N++EA +L++G+T YT
Sbjct: 4 YLSDYVQQIKPSGIRKFFDLAATMEGVISLGVGEPDFVTAWNVREASILSLEQGYTSYTA 63
Query: 68 NAGIQQLREAVVEYYKKFYDVDIDVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPAF 126
NAG+ LRE + Y +D+ +N +I+T GA + +A +++ G+EV+IP+P F
Sbjct: 64 NAGLYSLREEISRYLSNRFDLSYSPDNELIVTVGASQALDIAIRAIVNPGEEVIIPEPCF 123
Query: 127 VSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEV 186
V+Y LA PV + + F + VT+KT+ I+I P+NPTG+ KE
Sbjct: 124 VAYDALVSLAGGIPVHVHTTADKGFKATAADFEAAVTEKTKAILICSPSNPTGSVYSKEE 183
Query: 187 AKAIADIAQDYNIYILSDEPYEHFIYDDA-KHYPMLKFAPENTILANSFSKTFAMTGWRL 245
IA+ A+ +++ +L+DE Y YD+ L E T++ + FSK FAMTGWRL
Sbjct: 184 LNEIAEFAKKHDVIVLADEIYAELTYDEEFTSIAALPGMKERTVVISGFSKAFAMTGWRL 243
Query: 246 GFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVL 305
GF APS + M+K+H Y + + Q A +E L++ + V++M+K Y RR L +
Sbjct: 244 GFAAAPSLLRDAMLKIHQYAMMCAPAMAQFAALEGLKN--GMEDVEKMKKSYRRRRNLFV 301
Query: 306 KRLKEMPGIRVKEPKGAFYVFPSIKDTGMS-SEKFSEWLLEKARVVVI 352
+ L E+ G+ P G F F + G E LL + +V V+
Sbjct: 302 ESLNEI-GLSCHHPGGRFLCFSIYQKHGNEFKNSLPEELLTQEKVAVV 348
>gb|AAF65616.1|AF163769_1 (AF163769) alanine aminotransferase [Pyrococcus furiosus]
Length = 398
Score = 220 bits (555), Expect = 2e-56
Identities = 138/380 (36%), Positives = 208/380 (54%), Gaps = 20/380 (5%)
Query: 22 RELFERASKMENVISLGIGEP---DFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAV 78
REL ++ K VI L IG+P DF P+++KEA +A+ EG +Y + G+ +LR+A+
Sbjct: 23 RELEKKGIK---VIRLNIGDPVKFDFQPPEHMKEAYCKAIKEGHNYYGDSEGLPELRKAI 79
Query: 79 VEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEA 138
VE K+ VDI ++V +TA E L F +LL+ GDE+L+P P++ Y K
Sbjct: 80 VEREKRKNGVDITPDDVRVTAAVTEALQLIFGALLDPGDEILVPGPSYPPYTGLVKFYGG 139
Query: 139 KPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYN 198
KPV EE ++ PD D++ + +T +T+ I + PNNPTGA DK+ + I +IA +Y
Sbjct: 140 KPVEYRTIEEEDWQPDIDDIRKKITDRTKAIAVINPNNPTGALYDKKTLEEILNIAGEYE 199
Query: 199 IYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFV--VAP----S 252
I ++SDE Y+ Y+ P I+ N SK + TGWRLG++ V P S
Sbjct: 200 IPVISDEIYDLMTYEGEHISPGSLTKDVPVIVMNGLSKVYFATGWRLGYMYFVDPENKLS 259
Query: 253 EIIKEMIKLHAYII--GNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKE 310
E+ + + +L + A F +AG+ +KE K+ ERR + KRL E
Sbjct: 260 EVREAIDRLARIRLCPNTPAQFAAIAGLTG-----PMDYLKEYMKKLKERRDYIYKRLNE 314
Query: 311 MPGIRVKEPKGAFYVFPSIKDTGMSSEK-FSEWLLEKARVVVIPGTAFGKMGEGYVRISY 369
+PGI +P+GAFY+FP I+ ++K F +L A V+ + G+ FG+ G G+ R +
Sbjct: 315 IPGISTTKPQGAFYIFPKIEVGPWKNDKEFVLDVLHNAHVLFVHGSGFGEYGAGHFRAVF 374
Query: 370 ATSREKLMEAMDRMEKALSE 389
E L EAMDR EK + E
Sbjct: 375 LPPIEILEEAMDRFEKFMKE 394
>pir||A75128 probable transaminase (EC 2.6.1.-) aspB-like2 PAB1810 [similarity]
- Pyrococcus abyssi (strain Orsay)
>gi|5458249|emb|CAB49738.1| (AJ248285) aspartate
aminotransferase (aspB-like2) [Pyrococcus abyssi]
Length = 398
Score = 219 bits (553), Expect = 3e-56
Identities = 138/377 (36%), Positives = 207/377 (54%), Gaps = 14/377 (3%)
Query: 22 RELFERASKMENVISLGIGEP---DFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAV 78
REL ++ K VI L IG+P DF P+++KEA +A+ EG +Y + G+ +LREA+
Sbjct: 23 RELEKKGIK---VIRLNIGDPVKFDFQPPEHMKEAYCKAIKEGHNYYGDSEGLMELREAI 79
Query: 79 VEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEA 138
VE KK V+I ++V +TA E + F +LL+ GDE+LIP P++ Y K
Sbjct: 80 VEREKKKNGVNITPDDVRVTAAVTEALQMIFGALLDPGDEILIPGPSYPPYTGLVKFYGG 139
Query: 139 KPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYN 198
PV EE + PD D+L + +T++T+ I + PNNPTGA DK+ + I +IA +++
Sbjct: 140 VPVEYRTIEEEGWQPDIDDLRKKITERTKAIAVINPNNPTGALYDKKTLEEIINIAGEHD 199
Query: 199 IYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFV--VAPS---E 253
I +LSDE Y+ Y+ P I+ N SK + TGWRLG++ V P
Sbjct: 200 IPVLSDEIYDLMTYEGKHISPASLTKDVPVIVMNGLSKVYFATGWRLGYMYFVDPEGKLS 259
Query: 254 IIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPG 313
++E I A I + Q A + LR + ++E K+ ERR + KRL E+PG
Sbjct: 260 EVREAIDKLARIRLCPNTPAQFAAIAGLRGPMDY--LEEYMKKLKERRDYIYKRLNEIPG 317
Query: 314 IRVKEPKGAFYVFPSIKDTGMSSEK-FSEWLLEKARVVVIPGTAFGKMGEGYVRISYATS 372
I +P+GAFY+FP I++ +K F +L A V+ + G+ FG+ G G+ R +
Sbjct: 318 ISTTKPQGAFYIFPRIEEGPWKDDKEFVLDVLHNAHVLFVHGSGFGEYGRGHFRAVFLPP 377
Query: 373 REKLMEAMDRMEKALSE 389
E L EAM+R EK + E
Sbjct: 378 VEVLEEAMNRFEKFMRE 394
>sp|Q06191|AATB_RHIME ASPARTATE AMINOTRANSFERASE B (TRANSAMINASE A) (ASPAT)
>gi|538699|pir||A40658 aspartate transaminase (EC
2.6.1.1) - Rhizobium meliloti >gi|152151|gb|AAA71965.1|
(L12149) aspartate aminotransferase [Sinorhizobium
meliloti]
Length = 410
Score = 219 bits (551), Expect = 6e-56
Identities = 129/399 (32%), Positives = 210/399 (52%), Gaps = 22/399 (5%)
Query: 10 AERVILIKRSKIRELFERASKMEN----VISLGIGEPDFDTPKNIKEACKRALDEGWTHY 65
A R+ I S+I ++ RA+ M+ VI LG GEPDFDTP ++K+A A+ G T Y
Sbjct: 15 ASRISSIGVSEILKIGARAAAMKREGKPVIILGAGEPDFDTPDHVKQAASDAIHRGETKY 74
Query: 66 TPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPA 125
T G +L++A+ E +++ + +++ + + GA + + A + L+ GDEV+IP P
Sbjct: 75 TALDGTPELKKAIREKFQRENGLAYELDEITVATGAKQILFNAMMASLDPGDEVVIPTPY 134
Query: 126 FVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKE 185
+ SY + ++ E KP+ I + F +L +T +TR +++N P+NP+GA
Sbjct: 135 WTSYSDIVQICEGKPILIACDASSGFRLTAQKLEAAITPRTRWVLLNSPSNPSGAAYSAA 194
Query: 186 VAKAIADIAQDY-NIYILSDEPYEHFIYDDAKHYPMLKFAP---ENTILANSFSKTFAMT 241
+ + D+ + ++++L D+ YEH +YD + + P + T+ N SK +AMT
Sbjct: 195 DYRPLLDVLLKHPHVWLLVDDMYEHIVYDAFRFVTPARLEPGLKDRTLTVNGVSKAYAMT 254
Query: 242 GWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERR 301
GWR+G+ P +IK M + + +S Q A V AL + + +KE + + RR
Sbjct: 255 GWRIGYAGGPRALIKAMAVVQSQATSCPSSVSQAASVAALNGPQDF--LKERTESFQRRR 312
Query: 302 KLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGM----------SSEKFSEWLLEKARVVV 351
LV+ L + G+ + P+GAFY F S F +LLE + V V
Sbjct: 313 NLVVNGLNAIEGLDCRVPEGAFYTFSGCAGVARRVTPSGKRIESDTDFCAYLLEDSHVAV 372
Query: 352 IPGTAFGKMGEGYVRISYATSREKLMEAMDRMEKALSEL 390
+PG+AFG Y RISYATS +L EA++R+ A L
Sbjct: 373 VPGSAFGL--SPYFRISYATSEAELKEALERISAACKRL 409
>pir||E70338 probable aspartate transaminase (EC 2.6.1.1) aspC3 [similarity] -
Aquifex aeolicus >gi|2983083|gb|AAC06689.1| (AE000689)
aminotransferase (AspC family) [Aquifex aeolicus]
Length = 373
Score = 217 bits (547), Expect = 2e-55
Identities = 122/371 (32%), Positives = 214/371 (56%), Gaps = 11/371 (2%)
Query: 21 IRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVE 80
+ ++ +A K E+V+ + IGEPD + + EA +RA+ E YTP G+ +LRE + E
Sbjct: 12 VMDILAQAQKYEDVVHMEIGEPDLEPSPKVMEALERAVKEKTFFYTPALGLWELRERISE 71
Query: 81 YYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKP 140
+Y+K Y V++ E VI+T G +A+ L +G+++++PDP++ Y A L +A+P
Sbjct: 72 FYRKKYSVEVSPERVIVTTGTSGAFLVAYAVTLNAGEKIILPDPSYPCYKNFAYLLDAQP 131
Query: 141 VRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIY 200
V + + +E N+ E++E + K + I+ P NPTG E K +A+ ++ +Y
Sbjct: 132 VFVNVDKETNY-EVRKEMIEDIDAKA--LHISSPQNPTGTLYSPETLKELAEYCEEKGMY 188
Query: 201 ILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIK 260
+SDE Y +Y+ +H L+F+ + I+ N FSK F M G+R+G+++ P E++++
Sbjct: 189 FISDEIYHGLVYEGREH-TALEFS-DRAIVINGFSKYFCMPGFRIGWMIVPEELVRKAEI 246
Query: 261 LHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPK 320
+ + + + Q A +EA ++ ++++RK + ERR + LK++ I K P+
Sbjct: 247 VIQNVFISAPTLSQYAALEAF----DYEYLEKVRKTFEERRNFLYGELKKLFKIDAK-PQ 301
Query: 321 GAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGK-MGEGYVRISYATSREKLMEA 379
GAFYV+ +I D S +F+ LL +ARV V PG FGK + Y+R +Y E+L E
Sbjct: 302 GAFYVWANISDYSTDSYEFALKLLREARVAVTPGVDFGKNKTKEYIRFAYTRKIEELKEG 361
Query: 380 MDRMEKALSEL 390
++R++K L +L
Sbjct: 362 VERIKKFLEKL 372
>sp|P39643|AAT2_BACSU PROBABLE ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|629092|pir||S39740 probable transaminase (EC
2.6.1.-) ywfG [similarity] - Bacillus subtilis
>gi|414009|emb|CAA51641.1| (X73124) ipa-85d [Bacillus
subtilis] >gi|2636305|emb|CAB15796.1| (Z99123) alternate
gene name: ipa-85d~similar to aspartate aminotransferase
[Bacillus subtilis]
Length = 399
Score = 216 bits (545), Expect = 3e-55
Identities = 128/378 (33%), Positives = 209/378 (54%), Gaps = 11/378 (2%)
Query: 16 IKRSKIRELFERASKME----NVISLGIGEPDFDTPKNIKEACKRA-LDEGWTHYTPNAG 70
+ R + +F++ +ME ++I+LG G PD TP +I EA + A L+ + Y P G
Sbjct: 12 LPRQEFSLVFQKVKEMEKTGAHIINLGQGNPDLPTPPHIVEALREASLNPSFHGYGPFRG 71
Query: 71 IQQLREAVVEYYKKFYDVDIDVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSY 129
L+EA+ +YK+ Y V I+ E V + G G Y+ + LL GD L+P+P + Y
Sbjct: 72 YPFLKEAIAAFYKREYGVTINPETEVALFGGGKAGLYVLTQCLLNPGDIALVPNPGYPEY 131
Query: 130 VEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKA 189
+ +A A+ +PL EEN ++PD +++ V +K +++ +NYPNNPTGA D
Sbjct: 132 LSGITMARAELYEMPLYEENGYLPDFEKIDPAVLEKAKLMFLNYPNNPTGAVADAAFYAK 191
Query: 190 IADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILAN--SFSKTFAMTGWRLGF 247
A A+++NI+++ D Y F +D K L+ T+ A SFSKTF M GWR+ F
Sbjct: 192 AAAFAKEHNIHLIHDFAYGAFEFDQ-KPASFLEAEDAKTVGAELYSFSKTFNMAGWRMAF 250
Query: 248 VVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKR 307
V +II+ + + ++ + +Q A AL + + + +++ Y ER
Sbjct: 251 AVGNEKIIQAVNEFQDHVFVGMFGGLQQAASAALSGDP--EHTESLKRIYKERIDFFTAL 308
Query: 308 LKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRI 367
++ G ++++PKG FYV+ I +T +S +FS++LLE A VVV PG FG G+ +VRI
Sbjct: 309 CEKELGWKMEKPKGTFYVWAEIPNTFETSHQFSDYLLEHAHVVVTPGEIFGSNGKRHVRI 368
Query: 368 SYATSREKLMEAMDRMEK 385
S + +E L E + R++K
Sbjct: 369 SMVSKQEDLREFVTRIQK 386
>gi|11498021 aspartate aminotransferase (aspB-4) [Archaeoglobus fulgidus]
>gi|7447816|pir||A69301 probable transaminase (EC
2.6.1.-) aspB4 AF0409 [similarity] - Archaeoglobus
fulgidus >gi|2650220|gb|AAB90825.1| (AE001076) aspartate
aminotransferase (aspB-4) [Archaeoglobus fulgidus]
Length = 386
Score = 215 bits (542), Expect = 7e-55
Identities = 130/385 (33%), Positives = 209/385 (53%), Gaps = 18/385 (4%)
Query: 7 YFIAERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYT 66
Y AE + +KR K++E + VI G+G+PD TP++I EA K A ++
Sbjct: 14 YLFAE-IDAMKRKKLQEGVK-------VIDFGVGDPDLPTPEHIVEALKNAAEKVERQKY 65
Query: 67 PN-AGIQQLREAVVEYYKKFYDVDIDVENVIITA-GAYEGTYLAFESLLESGDEVLIPDP 124
P+ G+ RE+V +Y++ V++D E+ +I+ G+ EG + + GD VL+P+P
Sbjct: 66 PSYEGMLSFRESVARFYRRRKGVNLDPESEVISLIGSKEGIAHLPLAFVNDGDYVLVPEP 125
Query: 125 AFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDK 184
+ Y LA+ P +PL+EEN F+PD + + + +K +++ +NYPNNPT A K
Sbjct: 126 GYPVYYSSTLLADGVPYEMPLKEENKFLPDFQLIPDEIARKAKIMFLNYPNNPTAAVAPK 185
Query: 185 EVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKF--APENTILANSFSKTFAMTG 242
E K D D I + D Y +D K L+F A E + NS SKT+ MTG
Sbjct: 186 EFIKEAIDFCIDNKIILAHDAAYSEITFDGYKAPSFLEFEDAFEVCVEFNSLSKTYNMTG 245
Query: 243 WRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRK 302
WR+GF +I+ ++K+ + V IQ A + A+ + + ++E K Y RR
Sbjct: 246 WRIGFACGNRDILAGLLKVKTNVDSGVFEAIQEAAIAAMDGPD--RVIEENCKVYQRRRD 303
Query: 303 LVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGE 362
L+++ L+++ GI ++PK FYV+ + G SS +F + L++KA +V PG FGK GE
Sbjct: 304 LLVEGLRDV-GIDAEKPKATFYVWAKV---GGSSIEFVKQLIDKAGIVATPGIGFGKSGE 359
Query: 363 GYVRISYATSREKLMEAMDRMEKAL 387
G+VR + + EA+DR++ L
Sbjct: 360 GFVRFALTRGEGVIEEAIDRLKTIL 384
>gb|AAG00592.1| (AF289216) alanine aminotransferase [Thermococcus sp. TK1]
Length = 397
Score = 213 bits (536), Expect = 3e-54
Identities = 135/381 (35%), Positives = 206/381 (53%), Gaps = 22/381 (5%)
Query: 22 RELFERASKMENVISLGIGEP---DFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAV 78
REL ++ K +I L IG+P DF P+++K+A A+ EG +Y + G ++LREA+
Sbjct: 23 RELEKQGIK---IIKLNIGDPVKFDFQPPEHMKKAYCEAIMEGHNYYGDSEGDRELREAI 79
Query: 79 VEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEA 138
VE KK VDI E+V +TA E F +L++ G+E+LIP P++ YV K
Sbjct: 80 VEREKKKNGVDITPEDVQVTAAVTEALQFIFGALIDGGEEILIPGPSYPPYVGLVKFYGG 139
Query: 139 KPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYN 198
P EE + PD D++ + +T+KT+ I + PNNPTGA +K+ + I D+A +Y+
Sbjct: 140 VPKAYRTVEEEGWQPDIDDMRKKITEKTKAIAVINPNNPTGALYEKKTLQEIIDLAGEYD 199
Query: 199 IYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFV--VAPSEIIK 256
+ I+SDE Y+ Y+ P I+ N SK + TGWRLG++ V P +
Sbjct: 200 LPIISDEIYDLMTYEGKHVSPGSLTKDVPVIVMNGLSKVYFATGWRLGYMYFVDPENKLA 259
Query: 257 EMIKLHAYIIGNVASF-------IQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLK 309
E+ + IG +A Q A + LR + ++E + ERR + KRL
Sbjct: 260 EVRE----AIGKLARIRLCPNTPAQKAAIAGLRGPMDY--LEEYMAKLKERRDYIYKRLN 313
Query: 310 EMPGIRVKEPKGAFYVFPSIKDTGMSSEK-FSEWLLEKARVVVIPGTAFGKMGEGYVRIS 368
EMPGI ++P+GAFY+FP I++ S+K F +L A V+ + G+ FG+ GE + R
Sbjct: 314 EMPGISTQKPQGAFYIFPKIEEGPWKSDKEFVLDVLHNAHVLFVHGSGFGEGGEMHFRSI 373
Query: 369 YATSREKLMEAMDRMEKALSE 389
+ L EAMD +EK + E
Sbjct: 374 FLAPVPVLEEAMDNLEKFMKE 394
>dbj|BAB04779.1| (AP001510) aspartate aminotransferase [Bacillus halodurans]
Length = 395
Score = 204 bits (514), Expect = 1e-51
Identities = 125/369 (33%), Positives = 199/369 (53%), Gaps = 8/369 (2%)
Query: 21 IRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTH-YTPNAGIQQLREAVV 79
+ ++ E +++I+LG G PD TP++I E + A + H Y P +G L+EAV
Sbjct: 22 VEQVQEVKKDHDDIINLGQGSPDLPTPEHIVEKLQEAAENPLYHRYAPFSGYPFLKEAVS 81
Query: 80 EYYKKFYDVDIDVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEA 138
+YY++ Y V +D + V + GA G + L GD L+PDP + Y +A
Sbjct: 82 KYYEREYGVSVDPKTEVAVLGGAKTGLVEVSQCFLNPGDMALVPDPGYPDYWSGIAIAGG 141
Query: 139 KPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYN 198
+PL++E F PD + V + +++ +NYPNNPTGA +E+ ++A++Y+
Sbjct: 142 SMYGMPLKKELGFHPDLRGIPAPVLYEAKLMFLNYPNNPTGAVATEELFAEAIELAEEYD 201
Query: 199 IYILSDEPYEHFIYDDAKHYPMLKF--APENTILANSFSKTFAMTGWRLGFVVAPSEIIK 256
I ++ D Y +D K L+ A I + SK + M GWR+GF V +IK
Sbjct: 202 ICVVHDFAYSAIGFDGQKPLSFLQVEGAKNVGIEMITLSKNYNMAGWRIGFAVGNPSVIK 261
Query: 257 EMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRV 316
+ L + ++ IQ A AL S++S V + + Y ERR ++K + + G V
Sbjct: 262 AIETLQDHYFCSLFGGIQAAAAHALLSDQS--NVTTLVQTYEERRNALVKAARAI-GWDV 318
Query: 317 KEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKL 376
+ PKG+F+ + + +G +SE+F+ +LL+KARVVV PG FG+ GEGYVR++ KL
Sbjct: 319 EAPKGSFFAWFPV-PSGFTSEEFATYLLKKARVVVAPGKGFGEHGEGYVRVALLADIAKL 377
Query: 377 MEAMDRMEK 385
EAM R+ K
Sbjct: 378 EEAMGRVGK 386
>emb|CAC11898.1| (AL445065) aspartate transaminase related protein [Thermoplasma
acidophilum]
Length = 385
Score = 198 bits (498), Expect = 1e-49
Identities = 129/371 (34%), Positives = 198/371 (52%), Gaps = 20/371 (5%)
Query: 20 KIRE-LFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAV 78
KIR+ L E + V L G+P F P++++ A + AL + THYT + GI +LR+A+
Sbjct: 21 KIRDQLLEMQRAGKKVYRLESGDPSFPIPEHVRLAIEDALKKNRTHYTDSTGIPELRKAI 80
Query: 79 VEYYKKFYDV-DIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAE 137
E K + ENV+++ G Y+ F SL+ G++V+IPDP + E KLA+
Sbjct: 81 AEKLVKKNGIRSATPENVLVSNGGMNALYITFRSLIAPGEKVIIPDPMWTEIAEIIKLAD 140
Query: 138 AKPVRIPLR---EENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIA 194
P+RIP+ EE + D + R + IN P+NPTG ++ I D A
Sbjct: 141 GIPIRIPVERYVEEMRKYENDD--------RVRAVFINSPHNPTGYVFGEKQISDIIDFA 192
Query: 195 QDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPSEI 254
+ I+I+SDE YE I+D KH ++TI S SK++AM+G R+G+ +EI
Sbjct: 193 ESKGIFIVSDEAYEDVIFDGLKHLSPGSLY-DDTISLFSMSKSYAMSGLRIGYAHTSNEI 251
Query: 255 IKE-MIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPG 313
+ + M KL I V S Q V AL + + + EMRKEY +RR ++ + + E
Sbjct: 252 LYDRMKKLLRCTINGVNSATQYGAVAALTGPQDY--IGEMRKEYQKRRDIIYEAVSESRY 309
Query: 314 IRVKEPKGAFYVFPSIKD--TGMS-SEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYA 370
+ +P G FY++ IK+ G+S S + +LLEK V PG FG GEGY+R +++
Sbjct: 310 LEPIKPHGTFYLWNRIKEYPPGVSDSWGMTSYLLEKTGVGSSPGPVFGPAGEGYIRFAFS 369
Query: 371 TSREKLMEAMD 381
+ + + EA D
Sbjct: 370 AATDHIQEAAD 380
>pir||F69863 probable transaminase (EC 2.6.1.-) ykrV [similarity] - Bacillus
subtilis >gi|2633729|emb|CAB13231.1| (Z99111) similar to
aspartate aminotransferase [Bacillus subtilis]
Length = 398
Score = 198 bits (497), Expect = 1e-49
Identities = 122/371 (32%), Positives = 197/371 (52%), Gaps = 8/371 (2%)
Query: 19 SKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTH-YTPNAGIQQLREA 77
S ++++ + ++ +VI+LG G PD TP++I E KRA+ + H Y+ G +L+ A
Sbjct: 19 SLVQKVNRKLAEGHDVINLGQGNPDQPTPEHIVEEMKRAVADPENHKYSSFRGSYRLKSA 78
Query: 78 VVEYYKKFYDVDIDVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLA 136
+YK+ Y +D+D E V + G G + LL GD +L+PDP + Y LA
Sbjct: 79 AAAFYKREYGIDLDPETEVAVLFGGKAGLVELPQCLLNPGDTILVPDPGYPDYWSGVTLA 138
Query: 137 EAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQD 196
+AK +PL ++ F+PD + + ++ +++ +NYPNNPTGA E + A +
Sbjct: 139 KAKMEMMPLVKDRAFLPDYSSITAEIREQAKLMYLNYPNNPTGAVATSEFFEDTVRFAAE 198
Query: 197 YNIYILSDEPYEHFIYDDAKHYPMLKF--APENTILANSFSKTFAMTGWRLGFVVAPSEI 254
I ++ D Y +D K L+ A + I + SKT+ M GWR+GF V + +
Sbjct: 199 NGICVVHDFAYGAVGFDGCKPLSFLQTEGAKDIGIEIYTLSKTYNMAGWRVGFAVGNASV 258
Query: 255 IKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGI 314
I+ + ++ ++ Q A EAL ++++ V E Y RR + +E+ G
Sbjct: 259 IEAINLYQDHMFVSLFRATQEAAAEALLADQT--CVAEQNARYESRRNAWITACREI-GW 315
Query: 315 RVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSRE 374
V P G+F+ + + + G +SE+FS+ LLEKA V V G FG+ GEGYVR+ TS E
Sbjct: 316 DVTAPAGSFFAWLPVPE-GYTSEQFSDLLLEKANVAVAAGNGFGEYGEGYVRVGLLTSEE 374
Query: 375 KLMEAMDRMEK 385
+L EA R+ K
Sbjct: 375 RLKEAAYRIGK 385
>pir||T36548 probable transaminase (EC 2.6.1.-) SCH10.36 [similarity] -
Streptomyces coelicolor >gi|4753882|emb|CAB42045.1|
(AL049754) putative aspartate aminotransferase
[Streptomyces coelicolor A3(2)]
Length = 396
Score = 189 bits (474), Expect = 6e-47
Identities = 122/359 (33%), Positives = 190/359 (51%), Gaps = 12/359 (3%)
Query: 35 ISLGIGEPDFDTPKNIKEACKRALDEG-WTHYTPNAGIQQLREAVVEYYKKFYDVDIDVE 93
I+LG G PD D P+ ++EA RAL +G Y P G+ +LR AV + ++ Y + D +
Sbjct: 37 INLGQGFPDTDGPEEVREAAVRALRDGRGNQYPPGPGVPELRAAVAGHQQRRYGLSYDPD 96
Query: 94 N-VIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLR-EENNF 151
V++TAGA E A +LLE GDEV+ +P + SY +A V + LR E F
Sbjct: 97 TEVLVTAGATEAIAAALLALLEPGDEVVALEPYYDSYAACIAMAGGTRVPVTLRPHEGTF 156
Query: 152 MPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHFI 211
D DEL + VT +TR++++N P+NPTG L ++ AIA++A + ++ +++DE YEH +
Sbjct: 157 RLDLDELRDAVTDRTRLLLLNTPHNPTGTVLTRDELAAIAELAVERDLLVVTDEVYEHLV 216
Query: 212 YDDAKHYPMLKF--APENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNV 269
+ A+H P+ F E T+ S KTF+ TGW++G+V A ++ + Y+
Sbjct: 217 FGTAEHIPLASFPGMRERTVTIGSAGKTFSFTGWKVGWVTAAPALLTAVRSAKQYLTYVA 276
Query: 270 ASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSI 329
+ Q A EAL ES+ A R++ +R L+ L E G V P G ++V I
Sbjct: 277 SGPFQYAVAEALALPESYFAA--YRQDMEAKRDLLAAGLAE-AGFGVYRPAGTYFVTTDI 333
Query: 330 KDTG-MSSEKFSEWLLEKARVVVIPGTAF---GKMGEGYVRISYATSREKLMEAMDRME 384
+ G F L E+A VV +P F + G +VR ++ L EA+ R++
Sbjct: 334 RPLGERDGFAFCRSLPERAGVVAVPNAVFYNHREEGAPFVRFAFCKRLPVLEEAVGRLK 392
>gb|AAD56921.1|AF180145_13 (AF180145) aspartate aminotransferase A [Zymomonas mobilis]
Length = 397
Score = 188 bits (472), Expect = 1e-46
Identities = 104/318 (32%), Positives = 180/318 (55%), Gaps = 9/318 (2%)
Query: 19 SKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAV 78
S + + E SK ++I+LG GEPDF+TP+ IKEA +A+ +G T YT G +L+EA+
Sbjct: 62 SVLSVMIELKSKGVDIITLGAGEPDFETPEFIKEAAIQAIHDGKTRYTNVDGTAELKEAI 121
Query: 79 VEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEA 138
V +++ ++ + + + +G + A + ++ GDEV+IP P +VSY + +
Sbjct: 122 VGKFRRDNHLEYRTDQISVGSGGKHVLFNALTATIDQGDEVIIPAPYWVSYPDIVRFCGG 181
Query: 139 KPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDY- 197
PV I + ++ ++L + +T+KTR + N P+NPTGA + K++A++ + +
Sbjct: 182 TPVFIQATIDQDYKITAEQLEKAITQKTRWFIFNSPSNPTGAAYSADEIKSLAEVLRRHP 241
Query: 198 NIYILSDEPYEHFIYDDAKHYPMLKFAP---ENTILANSFSKTFAMTGWRLGFVVAPSEI 254
+++ILSD+ YEH ++D+ + + + AP + T+ AN SK +AMTGWR+GF P+ +
Sbjct: 242 HVWILSDDIYEHIVFDNFRFATIAEVAPDLFDRTLTANGCSKAYAMTGWRIGFAGGPTPL 301
Query: 255 IKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGI 314
IK M KL + N S Q A V AL + + ++ ++ RR LV+ L + GI
Sbjct: 302 IKAMAKLQSQSTSNPCSISQAAAVAALNGPQDF--LQGWSDDFARRRNLVVDGLNAIEGI 359
Query: 315 ---RVKEPKGAFYVFPSI 329
+ + P + FPS+
Sbjct: 360 SCPKPQVPSMSIRAFPSL 377
>gb|AAF07797.1|AC010704_22 (AC010704) putative aminotransferase; 101422-99564 [Arabidopsis
thaliana]
Length = 440
Score = 187 bits (470), Expect = 2e-46
Identities = 123/385 (31%), Positives = 207/385 (52%), Gaps = 11/385 (2%)
Query: 9 IAERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPN 68
+A+R+ K + ++ A K I+LG G P+FD P +KEA +A+ +G Y
Sbjct: 57 VAKRLEKFKTTIFTQMSILAVK-HGAINLGQGFPNFDGPDFVKEAAIQAIKDGKNQYARG 115
Query: 69 AGIQQLREAVVEYYKKFYDVDIDVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
GI QL A+ +++ + +D E V +T+G E A L+ GDEV++ P +
Sbjct: 116 YGIPQLNSAIAARFREDTGLVVDPEKEVTVTSGCTEAIAAAMLGLINPGDEVILFAPFYD 175
Query: 128 SYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVA 187
SY +A AK I LR + +P +EL VT KTR I++N P+NPTG +E
Sbjct: 176 SYEATLSMAGAKVKGITLRPPDFSIP-LEELKAAVTNKTRAILMNTPHNPTGKMFTREEL 234
Query: 188 KAIADIAQDYNIYILSDEPYEHFIYD-DAKHYPMLKFAPENTILANSFSKTFAMTGWRLG 246
+ IA + + ++ + SDE Y+ ++ D L E T+ NS KTF++TGW++G
Sbjct: 235 ETIASLCIENDVLVFSDEVYDKLAFEMDHISIASLPGMYERTVTMNSLGKTFSLTGWKIG 294
Query: 247 FVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLK 306
+ +AP + + + H+Y+ ++ Q A V AL++ ES+ KE++++YN +++ ++K
Sbjct: 295 WAIAPPHLTWGVRQAHSYLTFATSTPAQWAAVAALKAPESY--FKELKRDYNVKKETLVK 352
Query: 307 RLKEMPGIRVKEPKGAFYVFPSIKDTGMSSE-KFSEWLLEKARVVVIPGTAF---GKMGE 362
LKE+ G V G ++V GM ++ F E+L+E+ VV IP + F + G+
Sbjct: 353 GLKEV-GFTVFPSSGTYFVVADHTPFGMENDVAFCEYLIEEVGVVAIPTSVFYLNPEEGK 411
Query: 363 GYVRISYATSREKLMEAMDRMEKAL 387
VR ++ E L A++RM++ L
Sbjct: 412 NLVRFAFCKDEETLRGAIERMKQKL 436
>pir||D70479 probable transaminase (EC 2.6.1.-) aspC2 [similarity] - Aquifex
aeolicus >gi|2984300|gb|AAC07823.1| (AE000772)
aminotransferase (AspC family) [Aquifex aeolicus]
Length = 414
Score = 186 bits (468), Expect = 3e-46
Identities = 118/374 (31%), Positives = 205/374 (54%), Gaps = 22/374 (5%)
Query: 32 ENVISLGIGEPDFDTPKNI-KEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYDVDI 90
E+V+ LG+G P+ K+I + C+ A Y+ + GI +LR+A+ +Y++ Y V +
Sbjct: 36 EDVVDLGMGNPNMPPAKHIIDKLCEVAQKPNVHGYSASRGIPRLRKAICNFYEERYGVKL 95
Query: 91 DVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREEN 149
D E I+T GA EG +++ GD V++P+P + + +A + IPL
Sbjct: 96 DPEREAILTIGAKEGYSHLMLAMISPGDTVIVPNPTYPIHYYAPIIAGGEVHSIPL---- 151
Query: 150 NFMPDPD----------ELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNI 199
NF D D E+++ K + +VI++P+NPT T++K+ K I A+++ +
Sbjct: 152 NFSDDQDHQEEFLRRLYEIVKTAMPKPKAVVISFPHNPTTITVEKDFFKEIVKFAKEHGL 211
Query: 200 YILSDEPYEHFIYDDAKHYPMLKF--APENTILANSFSKTFAMTGWRLGFVVAPSEIIKE 257
+I+ D Y +D K +L+ A + + S SK F+M GWR+ FVV +IK
Sbjct: 212 WIIHDFAYADIAFDGYKPPSILEIEGAKDVAVELYSMSKGFSMAGWRVAFVVGNEILIKN 271
Query: 258 MIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVK 317
+ L +Y+ + + IQVA + AL E ++ V++ K Y +RR ++++ L + G +VK
Sbjct: 272 LAHLKSYLDYGIFTPIQVASIIAL--ESPYEIVEKTAKVYQKRRDVLVEGLNRL-GWKVK 328
Query: 318 EPKGAFYVFPSIKD-TGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKL 376
+PK +V+ I + M+S FS +LL++A+V V PG FG+ GEGYVR + + ++
Sbjct: 329 KPKATMFVWAKIPEWINMNSLDFSLFLLKEAKVAVSPGVGFGQYGEGYVRFALVENEHRI 388
Query: 377 MEAMDRMEKALSEL 390
+A+ + KA +L
Sbjct: 389 RQAIRGIRKAFRKL 402
>pir||S76353 probable aspartate transaminase (EC 2.6.1.1) aspC sll0006
[similarity] - Synechocystis sp. (strain PCC 6803)
>gi|1001578|dbj|BAA10205.1| (D64000) aspartate
aminotransferase [Synechocystis sp.]
Length = 394
Score = 186 bits (467), Expect = 4e-46
Identities = 116/358 (32%), Positives = 196/358 (54%), Gaps = 8/358 (2%)
Query: 33 NVISLGIGEPDFDTPKNIKEACKRALDEGWTH-YTPNAGIQQLREAVVEYYKKFYDVDID 91
++I LG+G PD P+ I EA L+ +H Y P G Q R+++ +Y + Y VD+D
Sbjct: 36 DLIDLGMGNPDGKAPQPIIEAAIAELENPESHGYPPFEGTQSFRQSITRWYARQYGVDLD 95
Query: 92 VENVIITA-GAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENN 150
++ + G+ EG + + GD VL+P P++ ++ +A A+ I L +++
Sbjct: 96 PDSEALPLIGSKEGLGHLALAYVNPGDLVLVPTPSYPAHFRGPLIAGAEIYPIMLSAKDD 155
Query: 151 FMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHF 210
++ D++ E + ++ +++ NYPNNPT AT +E +AI D A+ Y I ++ D Y
Sbjct: 156 WLIQLDQIPEAIAQRAKILYFNYPNNPTTATAPREFYEAITDWARHYQIMLVHDLCYAEL 215
Query: 211 IYDDAKHYPMLKF--APENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGN 268
+D + +L+ A + ++ ++ SKT+ M GWR+GFVV EII+ + L +
Sbjct: 216 AFDGYQPTSLLEIPGAKDFSVEFHTLSKTYNMAGWRVGFVVGNQEIIQGLRTLKTNLDYG 275
Query: 269 VASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPS 328
+ +Q A AL ES+ ++ +RK Y ERR V+ L ++ G + + Y++
Sbjct: 276 IFRVVQKAAETALSLPESY--IEVVRKRYQERRDFVINGLSKL-GWSITPSQATMYLWVP 332
Query: 329 IKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAMDRMEKA 386
GMSS F+ +LEK VV+ PG AFG+ GE YVR+S ++L EA+ R+E+A
Sbjct: 333 C-PVGMSSTDFALTVLEKTGVVMTPGNAFGEGGERYVRLSLIADGDRLGEALQRIEQA 389
>pir||E83056 probable aminotransferase PA4715 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9950974|gb|AAG08101.1|AE004885_6 (AE004885) probable
aminotransferase [Pseudomonas aeruginosa]
Length = 411
Score = 185 bits (466), Expect = 5e-46
Identities = 106/355 (29%), Positives = 199/355 (55%), Gaps = 9/355 (2%)
Query: 32 ENVISLGIGEPDFDTPKNIKEA-CKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYDVDI 90
E++I L +G PD TP +I E C A E Y+ + GI +LR A+ +Y+ YDV I
Sbjct: 36 EDIIDLSMGNPDGPTPPHIVEKLCTVAQREDTHGYSTSRGIPRLRRAISHWYRDRYDVQI 95
Query: 91 DVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREEN 149
D E+ I+T G+ EG + L+ GD +L+P+P++ ++ A +A A+ +PL
Sbjct: 96 DPESEAIVTIGSKEGLAHLMLATLDHGDTILVPNPSYPIHIYGAVIAGAQVRSVPLVPGI 155
Query: 150 NFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEH 209
+F + + + K RM+++ +P+NPT ++ + + + +A+ Y++ ++ D Y
Sbjct: 156 DFFNELERAIRESIPKPRMMILGFPSNPTAQCVELDFFERVVALAKQYDVMVVHDLAYAD 215
Query: 210 FIYDDAKHYPMLKFAPENTILANSF--SKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIG 267
+YD K +++ I F SK++ M GWR+GF+V E++ + ++ +Y
Sbjct: 216 IVYDGWKAPSIMQVPGAKDIAVEFFTLSKSYNMAGWRIGFMVGNPELVSALARIKSYHDY 275
Query: 268 NVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFP 327
+ +QVA + AL ++ + V+++ ++Y +RR +++K L+E G V+ PK + YV+
Sbjct: 276 GTFTPLQVAAIAALEGDQ--QCVRDIARQYQQRRDVLVKGLRE-AGWMVENPKASMYVWA 332
Query: 328 SIKD--TGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAM 380
I + + S +F++ LL+ A+V V PG FG G+ +VR + +R++L +A+
Sbjct: 333 KIPEPYAHLGSLEFAKKLLQDAKVSVSPGIGFGDYGDDHVRFALIENRDRLRQAV 387
>sp|P77434|YFDZ_ECOLI HYPOTHETICAL AMINOTRANSFERASE YFDZ >gi|7447814|pir||H65011 probable
transaminase (EC 2.6.1.-) b2379 [similarity] -
Escherichia coli (strain K-12)
>gi|1788722|gb|AAC75438.1| (AE000326) putative
aminotransferase [Escherichia coli K12]
>gi|1799790|dbj|BAA16249.1| (D90868) PROBABLE ASPARTATE
AMINOTRANSFERASE (EC 2.6.1.1) (TRANSAMINASE A) (ASPAT).
[Escherichia coli]
Length = 412
Score = 180 bits (453), Expect = 2e-44
Identities = 104/355 (29%), Positives = 196/355 (54%), Gaps = 9/355 (2%)
Query: 32 ENVISLGIGEPDFDTPKNIKEACKRALDEGWTH-YTPNAGIQQLREAVVEYYKKFYDVDI 90
E++I +G PD TP +I E TH Y+ + GI +LR A+ +Y+ YDV+I
Sbjct: 36 EDIIDFSMGNPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLRRAISRWYQDRYDVEI 95
Query: 91 DVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREEN 149
D E+ I+T G+ EG + L+ GD VL+P+P++ ++ A +A A+ +PL E
Sbjct: 96 DPESEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGV 155
Query: 150 NFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEH 209
+F + + + K +M+++ +P+NPT ++ E + + +A+ Y++ ++ D Y
Sbjct: 156 DFFNELERAIRESYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYAD 215
Query: 210 FIYDDAKHYPMLKFAPENTILANSF--SKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIG 267
+YD K +++ + F SK++ M GWR+GF+V ++ + ++ +Y
Sbjct: 216 IVYDGWKAPSIMQVPGARDVAVEFFTLSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDY 275
Query: 268 NVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFP 327
+ +QVA + AL ++ + V+++ ++Y RR +++K L E G V+ PK + YV+
Sbjct: 276 GTFTPLQVAAIAALEGDQ--QCVRDIAEQYKRRRDVLVKGLHE-AGWMVEMPKASMYVWA 332
Query: 328 SIKD--TGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAM 380
I + M S +F++ LL +A+V V PG FG G+ +VR + +R+++ +A+
Sbjct: 333 KIPEPYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRIRQAI 387
>pir||T35706 probable aspartate transaminase (EC 2.6.1.1) SC7H1.11 [similarity]
- Streptomyces coelicolor >gi|2808769|emb|CAA16198.1|
(AL021411) aminotransferase [Streptomyces coelicolor
A3(2)]
Length = 382
Score = 179 bits (449), Expect = 5e-44
Identities = 119/381 (31%), Positives = 193/381 (50%), Gaps = 19/381 (4%)
Query: 19 SKIRELFERASKME------NVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQ 72
S+I EL R+ + +SL +GEPDF TP + +A AL EG THY G++
Sbjct: 8 SRIAELRRRSRRPALAPAPPGAVSLAMGEPDFPTPPTVVQAAVSALREGHTHYADQRGLR 67
Query: 73 QLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVED 132
+LR A+ + D ++V++T GA + + GD V++P+PA+ Y +
Sbjct: 68 ELRAALAARLPERPGGAWDADDVLVTHGATAALAAVVLATVGPGDRVVVPEPAYSLYADL 127
Query: 133 AKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIAD 192
LA +PL + ++ D D L + MI N P+NPTG +E +A+
Sbjct: 128 VVLAGGTVDFVPLAPDLHW--DLDALAAALPGAAMMIFSN-PSNPTGIVHRREELEALGK 184
Query: 193 IAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPEN----TILANSFSKTFAMTGWRLGFV 248
+ ++ ++SDE Y Y H P+ E+ T+ +FSKT+AMTGWR+G++
Sbjct: 185 LLDGTDVLVVSDEAYHRLAYPG--HEPVSALEIESLRGRTVYVQTFSKTYAMTGWRVGYL 242
Query: 249 VAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRL 308
P E++ ++H G++ + +Q A + AL + V M Y +RR LV+ RL
Sbjct: 243 TGPREVLDAAAQVHRTWNGSLNTAVQHAALAALDLPDG--VVGAMADRYRQRRDLVVGRL 300
Query: 309 KEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRIS 368
+PG+ + P+GAFY F D SE + L +V+V G +G GEG++RIS
Sbjct: 301 SGVPGLHLVPPEGAFYGFLRY-DADRPSEMVAR-ELAACQVLVRAGAEYGPSGEGHLRIS 358
Query: 369 YATSREKLMEAMDRMEKALSE 389
+A S + L ++R+ + +E
Sbjct: 359 FAASEDDLWVGLERIVRYFAE 379
>pir||F81432 probable transaminase (EC 2.6.1.-) Cj0150c [similarity] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6967644|emb|CAB72634.1| (AL139074) aminotransferase
[Campylobacter jejuni]
Length = 400
Score = 178 bits (447), Expect = 9e-44
Identities = 107/371 (28%), Positives = 202/371 (53%), Gaps = 16/371 (4%)
Query: 32 ENVISLGIGEPDFDTPKNI-KEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYDVDI 90
E++I +G P+ TP++I + C+ A + + Y+ + GI +LR A+ +YK+ Y+V++
Sbjct: 33 EDIIDFSMGNPNGKTPQHIIDKLCESANKDKTSGYSTSMGIYKLRLAICNWYKRKYNVNL 92
Query: 91 DVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREEN 149
D EN V+ T G+ EG +++ GD ++P PA+ + + +A ++PL
Sbjct: 93 DPENEVVATMGSKEGFVNLARAIINPGDVAIVPTPAYPIHTQAFIIAGGNVAKMPLAYNE 152
Query: 150 NFMPDPDELLELVTKKT-------RMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYIL 202
F D ++ E + K + +V+N+P+NPT T +K + + A+ YI+
Sbjct: 153 KFELDENQFFENLHKTLNESIPCPKYVVVNFPHNPTTVTCEKSFYERLIATAKKERFYII 212
Query: 203 SDEPYEHFIYDDAKHYPMLKF--APENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIK 260
SD Y YDD K +L+ A + + + SK++ M GWR+GFVV ++ + K
Sbjct: 213 SDIAYADLTYDDYKTPSILEIEGAKDVAVETYTLSKSYNMAGWRVGFVVGNKRLVSALKK 272
Query: 261 LHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPK 320
+ ++ + + IQVA AL +++ V E+R Y++R ++L+ E G ++++P+
Sbjct: 273 IKSWFDYGMYTPIQVAATIALDGDQT--CVDEIRATYDKRMHILLEAF-ENAGWKLQKPR 329
Query: 321 GAFYVFPSIKDT--GMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLME 378
+ +V+ + ++ + S +FS+ LL++A V V PG FG+ G+ YVRI+ + ++ +
Sbjct: 330 ASMFVWAKLPESKRHLKSLEFSKQLLQRASVAVSPGVGFGEAGDEYVRIALIENENRIRQ 389
Query: 379 AMDRMEKALSE 389
A ++K L E
Sbjct: 390 AARNIKKYLKE 400
>emb|CAB45026.1| (AL078635) putative aminotransferase [Amycolatopsis orientalis]
Length = 394
Score = 178 bits (446), Expect = 1e-43
Identities = 111/382 (29%), Positives = 191/382 (49%), Gaps = 23/382 (6%)
Query: 22 RELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTH--------YTPNAGIQQ 73
+ + E A + + L +G P F P++ E + A+ H Y + G +
Sbjct: 14 KRISEYAQRHPGTVDLTVGLPAFGPPRSFDE--RLAMLSSAPHVNARPEDQYAHSRGAIE 71
Query: 74 LREAVVEYYKKFYDVDIDVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVED 132
LR A+ YK VD+D + +++T GA ++A +L E GDEVL+ DP ++ Y
Sbjct: 72 LRAAIAHVYKSEQGVDLDPDTQILVTNGAAGALWIAVLTLTEPGDEVLLADPGYMIYPPM 131
Query: 133 AKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIAD 192
+L + VRIP + F +L +T+++R++++N P NPTG ++ +
Sbjct: 132 IELLGRRVVRIPTSPADGFRLHLSDLRSRLTQRSRVVLVNSPGNPTGRVSSEDELADLCA 191
Query: 193 IAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENT-ILANSFSKTFAMTGWRLGFVVAP 251
A ++ +Y++ DE + F Y +H ++ + I N SK F M+GWR+G++ +
Sbjct: 192 FAVEHGLYVVHDEVLDRFAY-GIEHRSVVALDHQGVGIAVNGLSKRFGMSGWRIGWLASS 250
Query: 252 SEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEM 311
S +I E K H + + V+ +Q+A AL ++ V E R ++ L L +
Sbjct: 251 SAVIAEAAKAHTFFMLAVSHAVQLAAAAALSDPKADGEVSVYAAEIRRRGEVFLADLARI 310
Query: 312 PGI-RVKEPKGAFYVF---------PSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMG 361
PG+ + P G FY F I+ +S +E+LL + V V+PG+ FG+ G
Sbjct: 311 PGLGKTTVPDGGFYAFVDVGEFARLRGIRVAESTSAAVAEYLLHECGVAVVPGSVFGRAG 370
Query: 362 EGYVRISYATSREKLMEAMDRM 383
EG+VR+S+A S E+L A+ R+
Sbjct: 371 EGFVRMSFAGSAEQLDRAVKRL 392
>dbj|BAB04655.1| (AP001510) aspartate aminotransferase [Bacillus halodurans]
Length = 385
Score = 178 bits (446), Expect = 1e-43
Identities = 103/356 (28%), Positives = 179/356 (49%), Gaps = 5/356 (1%)
Query: 34 VISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYDVDIDVE 93
+I L IG PD P + + + + G+ EAV ++Y++ Y V++
Sbjct: 33 LIDLSIGSPDLPPPDFVVQKMNAYVSNPNQYGYAITGLAAFHEAVAQFYQRRYQVNVKPH 92
Query: 94 NVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENNFMP 153
V+ G+ +G + +++GD +L PDP + Y A +A A+ PL EEN FM
Sbjct: 93 QVLSLMGSQDGLAHLALAYVDAGDLLLAPDPGYPIYAASAHIAGAELYTYPLNEENQFMF 152
Query: 154 DPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHFIYD 213
D + L + V +K +++++NYP NPT A D+ + + ++NI I+ D Y ++D
Sbjct: 153 DVETLPDDVKQKAKLMIVNYPGNPTAAMADEAYFEKLVAFGIEHNILIVHDYAYSELLFD 212
Query: 214 DAKHYPMLKF--APENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVAS 271
+ + A E I NS SK+F + G R+G+ + I++ + L +++ V
Sbjct: 213 QREALSIFSVPRAFETAIEFNSLSKSFNIAGARIGYAIGAESILQPLAALKSHLDYGVFL 272
Query: 272 FIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIKD 331
+Q +EAL E A E ++E E+R+ ++ G V +P G +++ I D
Sbjct: 273 PVQYGAIEAL---EHGDAFLETQRELYEKRRNTFVEALQLNGWTVSKPGGGMFIWAKIPD 329
Query: 332 TGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAMDRMEKAL 387
G + F + +E A V+V PG AFGK GEGYVR++ +L +A +++ + L
Sbjct: 330 DGRDAMSFVKQAMEHAGVIVTPGHAFGKEGEGYVRMALVQPETELRKAANQLAQIL 385
>pir||D83057 probable aminotransferase PA4722 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9950981|gb|AAG08108.1|AE004885_13 (AE004885)
probable aminotransferase [Pseudomonas aeruginosa]
Length = 390
Score = 175 bits (440), Expect = 6e-43
Identities = 118/374 (31%), Positives = 192/374 (50%), Gaps = 12/374 (3%)
Query: 21 IRELFERASKME----NVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLRE 76
+ L RA++++ +VI L IGEPDF T + I EA + AL G T YT G+ LRE
Sbjct: 17 VMALLARANELQAAGHDVIHLEIGEPDFTTAEPIVEAGRAALAAGHTRYTAARGLPALRE 76
Query: 77 AVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLA 136
A+ ++Y + Y VD+D + V++T G LA L++ G L+ DP + +L
Sbjct: 77 AIAKFYGERYGVDLDPQRVLVTPGGSGALLLASSLLVDPGRHWLLADPGYPCNRHFLRLV 136
Query: 137 EAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQD 196
E +P+ ++ + PD + + ++ P NPTG LD++ ++ +
Sbjct: 137 EGAAQLVPVGPDSRYQLTPDLIERHWDSDSVGALVATPANPTGTLLDRDELAGLSGALKA 196
Query: 197 YNIYILSDEPYEHFIYD-DAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPSEII 255
+++ DE Y Y DA + ++ + NSFSK F MTGWRLG++VAP+ +
Sbjct: 197 RGGHLVVDEIYHGLTYGVDA---ASVLEVDDDAFVLNSFSKYFGMTGWRLGWLVAPTAAV 253
Query: 256 KEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMP-GI 314
E+ KL + + S Q A + A + ++E R+E+ RR +L L+E+ GI
Sbjct: 254 PELEKLAQNLYISAPSMAQQAAL-ACFEPTTIAILEERREEFARRRDFLLPALRELGFGI 312
Query: 315 RVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEG-YVRISYATSR 373
V EP+GAFY++ I G + F + +E V PG FG+ G +VR +Y +
Sbjct: 313 AV-EPEGAFYLYADISAFGGDAYAFCKHFIETEHVAFTPGLDFGRHQAGHHVRFAYTQNL 371
Query: 374 EKLMEAMDRMEKAL 387
+L EA++R+ + L
Sbjct: 372 PRLQEAVERIARGL 385
>emb|CAC03612.1| (AJ272538) putative aspartate amino transferase [Kluyvera
ascorbata]
Length = 401
Score = 175 bits (439), Expect = 8e-43
Identities = 102/355 (28%), Positives = 194/355 (53%), Gaps = 9/355 (2%)
Query: 32 ENVISLGIGEPDFDTPKNIKEACKRALDEGWTH-YTPNAGIQQLREAVVEYYKKFYDVDI 90
E++I +G PD TP +I E TH Y+ + GI +LR A+ +Y++ YDV+I
Sbjct: 36 EDIIDFSMGNPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLRRAISRWYQERYDVEI 95
Query: 91 DVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREEN 149
D E+ I+T G+ EG + L+ GD VL+P+P++ ++ A +A A+ +PL E
Sbjct: 96 DPEDEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGV 155
Query: 150 NFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEH 209
+F + + + K +M+++ +P+NPT ++ E + + +A+ Y++ ++ D Y
Sbjct: 156 DFFNELERAIRESYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYAD 215
Query: 210 FIYDDAKHYPMLKFAPENTILANSF--SKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIG 267
++D K +++ + F SK++ M GWR+GF+V ++ + ++ +Y
Sbjct: 216 IVFDGWKAPSIMQVPGARDVAVEFFTLSKSYNMAGWRIGFMVGNKTLVNALARIKSYHDY 275
Query: 268 NVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFP 327
+ +QVA + AL ++ + V ++ +Y RR +++K L E G V PK + YV+
Sbjct: 276 GTFTPLQVAAIAALEGDQ--QCVLDIAAQYKRRRDVLVKGLHE-AGWMVDMPKASMYVWA 332
Query: 328 SIKD--TGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAM 380
I + M S +F++ +L+ A+V V PG FG G+ +VR + +R+++ +A+
Sbjct: 333 KIPEQYAHMGSLEFAKKMLQDAKVCVSPGIGFGDYGDTHVRFALIENRDRIRQAI 387
>gb|AAG19511.1| (AE005042) aspartate aminotransferase; AspC2 [Halobacterium sp.
NRC-1]
Length = 391
Score = 175 bits (438), Expect = 1e-42
Identities = 108/379 (28%), Positives = 182/379 (47%), Gaps = 5/379 (1%)
Query: 10 AERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNA 69
+ER + ++ ERA+ +VI + +GEPDF P EA AL G YT +
Sbjct: 12 SERAAAVTPFAAMDVLERAADRADVIHMEVGEPDFAPPAAATEAAVDALRAGDDDYTTSR 71
Query: 70 GIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSY 129
G + LR+A+ YY Y V + E +++T G+ + ++ G V++ DP + Y
Sbjct: 72 GRRSLRDAISGYYAAEYGVSVPAERIVVTPGSSPALLTVLLATVDPGSAVVLSDPHYACY 131
Query: 130 VEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKA 189
+LA+ + L + F P + + T +++N P NPTGA +D E A
Sbjct: 132 PNFVRLADGVVRTVGLAPDAGFQPAVSDYDAAIGDDTAAMLLNSPGNPTGAVIDGESLSA 191
Query: 190 IADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVV 249
+ +A + ++SDE Y +D A H +L++ ++ + + SK + MTGWRLG+VV
Sbjct: 192 LVALADRTDTAVVSDEIYHGLAFDAAAH-SVLEYT-DDAFVIDGVSKRYGMTGWRLGWVV 249
Query: 250 APSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLK 309
P + + + + SF+Q A+R W + +R +Y RR ++ +
Sbjct: 250 CPRRYVDTINAIAQNTLICAPSFVQAGAEAAIRHGTDW--LDGVRADYRTRRDILCAAAE 307
Query: 310 EMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISY 369
P GA+Y+ + G ++ ++ LLE A V V PG FG YVR S+
Sbjct: 308 RWGFDPGYTPAGAYYMLLDVSRLG-AAPAVADALLETAGVAVTPGPDFGANATEYVRASF 366
Query: 370 ATSREKLMEAMDRMEKALS 388
A S + + EA+ R++ L+
Sbjct: 367 AVSTDAVREAVARIDAVLA 385
>pir||A83171 probable aminotransferase PA3798 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9949971|gb|AAG07185.1|AE004798_8 (AE004798) probable
aminotransferase [Pseudomonas aeruginosa]
Length = 382
Score = 174 bits (437), Expect = 1e-42
Identities = 112/376 (29%), Positives = 191/376 (50%), Gaps = 25/376 (6%)
Query: 24 LFERASKME---NVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVE 80
+F R S++ I+L G PDFD P ++EA R + G Y P G+ LRE V +
Sbjct: 13 IFTRMSQLAAECGAINLSQGFPDFDGPPELREAVGRHIAAGHNQYAPMTGLPALREQVAK 72
Query: 81 YYKKFYDVDIDVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAK 139
++FY + ++ V IT GA E + A ++L+ GDEV++ DP++ SY +LA +
Sbjct: 73 KIEQFYGRRVSADSEVTITPGATEAIFSAIQALVHPGDEVVVLDPSYDSYEPSVQLAGGR 132
Query: 140 PVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNI 199
V +PL + F D + E + +TR+++IN P+NP+GA + +E +A + +D +I
Sbjct: 133 CVHVPLALPD-FSIDWQRMAEAIGPRTRLVIINTPHNPSGALISREELDRLAALIRDRDI 191
Query: 200 YILSDEPYEHFIYDDAKHYPMLKFAP--ENTILANSFSKTFAMTGWRLGFVVAPSEIIKE 257
Y++SDE YEH ++D H +L + + +SF KT+ +TGW+ G+VVAP + E
Sbjct: 192 YLISDEVYEHLVFDGVAHTSVLSHDELYPRSFVVSSFGKTYHVTGWKTGYVVAPPALSAE 251
Query: 258 MIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVK 317
+ K+H Y+ + +Q A + + + ++++ Y +R L L + R
Sbjct: 252 LRKVHQYVNFCGVTPLQWALADYMAGHP--EHLRQLPGFYQAKRDLFCDLLLD-SRFRFT 308
Query: 318 EPKGAFY-------VFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEG---YVRI 367
G ++ + P + D M +EWL + V IP + F + VR
Sbjct: 309 RAPGTYFQCVDYSAIRPDLDDVAM-----AEWLTREHGVAAIPVSVFYEKAPDAMRLVRF 363
Query: 368 SYATSREKLMEAMDRM 383
YA E L +A +++
Sbjct: 364 CYAKREETLRQAAEKL 379
>pir||B70815 probable transaminase (EC 2.6.1.-) Rv0858c [similarity] -
Mycobacterium tuberculosis (strain H37RV)
>gi|2916917|emb|CAA17664.1| (AL022004) hypothetical
protein Rv0858c [Mycobacterium tuberculosis]
Length = 397
Score = 173 bits (435), Expect = 2e-42
Identities = 120/365 (32%), Positives = 180/365 (48%), Gaps = 19/365 (5%)
Query: 35 ISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYDVDIDVEN 94
++LG G PD D P + +A + A+ G Y P G LR A+ ++ + VD D E
Sbjct: 27 VNLGQGFPDEDGPPKMLQAAQDAIAGGVNQYPPGPGSAPLRRAIAAQRRRHFGVDYDPET 86
Query: 95 -VIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENN-FM 152
V++T GA E A L+E G EVL+ +P + SY +A A V +PL + F
Sbjct: 87 EVLVTVGATEAIAAAVLGLVEPGSEVLLIEPFYDSYSPVVAMAGAHRVTVPLVPDGRGFA 146
Query: 153 PDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHFIY 212
D D L VT +TR ++IN P+NPTGA L AIA+IA N+ +++DE YEH ++
Sbjct: 147 LDADALRRAVTPRTRALIINSPHNPTGAVLSATELAAIAEIAVAANLVVITDEVYEHLVF 206
Query: 213 DDAKHYPMLKF--APENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVA 270
D A+H P+ F E TI +S +K F TGW++G+ P+E+I + Y+
Sbjct: 207 DHARHLPLAGFDGMAERTITISSAAKMFNCTGWKIGWACGPAELIAGVRAAKQYLSYVGG 266
Query: 271 SFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIK 330
+ Q A AL +E++W V +R RR + L E+ G V + G +++ +
Sbjct: 267 APFQPAVALALDTEDAW--VAALRNSLRARRDRLAAGLTEI-GFAVHDSYGTYFLCADPR 323
Query: 331 DTGM-SSEKFSEWLLEKARVVVIPGTAFGKMGEG-----------YVRISYATSREKLME 378
G S +F L EK V IP +AF G VR ++ + L E
Sbjct: 324 PLGYDDSTEFCAALPEKVGVAAIPMSAFCDPAAGQASQQADVWNHLVRFTFCKRDDTLDE 383
Query: 379 AMDRM 383
A+ R+
Sbjct: 384 AIRRL 388
>pir||G72655 aspartate transaminase (EC 2.6.1.1) APE0674 [similarity] -
Aeropyrum pernix (strain K1) >gi|5104332|dbj|BAA79647.1|
(AP000060) 405aa long hypothetical aspartate
aminotransferase [Aeropyrum pernix]
Length = 405
Score = 173 bits (435), Expect = 2e-42
Identities = 114/385 (29%), Positives = 191/385 (49%), Gaps = 14/385 (3%)
Query: 17 KRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRAL-DEGWTH---YTPNAGIQ 72
K +RE R + +VI L G+P F P ++E +AL DEG+ YTP G
Sbjct: 23 KIDAVRERLAREGR--DVILLSTGQPGFLPPTFLRERLAQALLDEGFKRLYSYTPTPGYA 80
Query: 73 QLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVED 132
+REA+ E ++ +++++TAG E + ++LE GD+V++ DP + Y
Sbjct: 81 DVREAIAEDLAALGGPRMEPDDILVTAGGQEAMFATLSTILEPGDKVILMDPTYFGYRPI 140
Query: 133 AKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIAD 192
+ + + F PD + L E T+ + +V+ P+NPTG L E AK +AD
Sbjct: 141 VEYLGGRVEWVRAPPSLGFQPDEERLKEAFTRDVKAVVLVSPDNPTGRLLSTESAKLVAD 200
Query: 193 IAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPS 252
+A D +I+ DE Y+ ++ + +H + K AP+NTI N+FSK GWRLG++ P
Sbjct: 201 LAVDTGAWIVYDEAYKTLVF-EGEHVYLYKLAPDNTISINTFSKDPGFPGWRLGYLYGPG 259
Query: 253 EIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEY-NERRKLVLKRLKEM 311
I+ ++ + ++ S QVA L E E +E+ R + + L+EM
Sbjct: 260 WIVGKIRLVSEELVYCPPSIAQVAAKIYLEDREGRLRHLEYAREFLKTRMEAMAGALEEM 319
Query: 312 -PGIRVKEPKGAFYVFPSIKD----TGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVR 366
P P G+ ++ + ++SE S LL++ V +PG FG G+ +R
Sbjct: 320 LPEAVFARPGGSMFITVDLSSYLSKASITSEDLSVKLLDEESVATVPGRYFGPSGDTMLR 379
Query: 367 ISYAT-SREKLMEAMDRMEKALSEL 390
+S+AT + E++ E + R+ + L L
Sbjct: 380 LSFATETPERIREGIGRLARLLERL 404
>sp|P77806|YBDL_ECOLI HYPOTHETICAL AMINOTRANSFERASE YBDL >gi|7447838|pir||F64793 probable
transaminase (EC 2.6.1.-) ybdL [similarity] -
Escherichia coli >gi|1778518|gb|AAB40801.1| (U82598)
hypothetical protein [Escherichia coli]
>gi|1786816|gb|AAC73701.1| (AE000165) putative
aminotransferase [Escherichia coli K12]
>gi|4062217|dbj|BAA35230.1| (D90701) Aspartate
transaminase (EC 2.6.1.1) [Escherichia coli]
Length = 386
Score = 171 bits (429), Expect = 1e-41
Identities = 107/385 (27%), Positives = 197/385 (50%), Gaps = 19/385 (4%)
Query: 15 LIKRSKIREL-------FERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTP 67
LI +SK+ +L ++ I+L G PDFD P+ ++E + +G Y P
Sbjct: 6 LIPQSKLPQLGTTIFTQMSALAQQHQAINLSQGFPDFDGPRYLQERLAHHVAQGANQYAP 65
Query: 68 NAGIQQLREAVVEYYKKFYDVDIDVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPAF 126
G+Q LREA+ + ++ Y D ++ + +TAGA E Y A +L+ +GDEV+ DP++
Sbjct: 66 MTGVQALREAIAQKTERLYGYQPDADSDITVTAGATEALYAAITALVRNGDEVICFDPSY 125
Query: 127 VSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEV 186
SY L+ R+ L+ + F D E L++++TR++++N P+NP+ +
Sbjct: 126 DSYAPAIALSGGIVKRMALQPPH-FRVDWQEFAALLSERTRLVILNTPHNPSATVWQQAD 184
Query: 187 AKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAP--ENTILANSFSKTFAMTGWR 244
A+ + I+++SDE YEH + H +L E + +SF KT+ MTGW+
Sbjct: 185 FAALWQAIAGHEIFVISDEVYEHINFSQQGHASVLAHPQLRERAVAVSSFGKTYHMTGWK 244
Query: 245 LGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSE-ESWKAVKEMRKEYNERRKL 303
+G+ VAP+ I E+ K+H Y+ +V + Q+A + LR+E E + A+ + Y ++R +
Sbjct: 245 VGYCVAPAPISAEIRKVHQYLTFSVNTPAQLALADMLRAEPEHYLALPDF---YRQKRDI 301
Query: 304 VLKRLKEMPGIRVKEPKGAFYVFPSIKDTG-MSSEKFSEWLLEKARVVVIPGTAF--GKM 360
++ L E + + +G +++ + +F +WL ++ V IP + F
Sbjct: 302 LVNALNE-SRLEILPCEGTYFLLVDYSAVSTLDDVEFCQWLTQEHGVAAIPLSVFCADPF 360
Query: 361 GEGYVRISYATSREKLMEAMDRMEK 385
+R+ +A L+ A +R+ +
Sbjct: 361 PHKLIRLCFAKKESTLLAAAERLRQ 385
>sp|O87320|AATC_RHIME PUTATIVE AMINOTRANSFERASE AATC
Length = 405
Score = 171 bits (428), Expect = 2e-41
Identities = 112/387 (28%), Positives = 196/387 (49%), Gaps = 21/387 (5%)
Query: 20 KIREL----FERASKME--------NVISLGIGEPDFDTPKNIKEACKRALDEGWTH-YT 66
K+R L FE+ ++++ ++I LG+G PD TP++I + + + TH Y+
Sbjct: 6 KVRRLPPYVFEQVNRLKASARAAGADIIDLGMGNPDLPTPQSIVDKLCEVVQDPRTHRYS 65
Query: 67 PNAGIQQLREAVVEYYKKFYDVDIDVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPA 125
+ GI LR A YY + + V ++ E V+ T G+ EG +++ GD VL P+P
Sbjct: 66 SSKGIPGLRRAQAAYYARRFGVKLNPETQVVATLGSKEGFANMAQAITAPGDVVLCPNPT 125
Query: 126 FVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKE 185
+ + +A I + + +F P + + K +++NYP+NPT +
Sbjct: 126 YPIHAFGFLMAGGVIRSISVEPDESFFPPLERAVRHSIPKPLALILNYPSNPTAQVATLD 185
Query: 186 VAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKF--APENTILANSFSKTFAMTGW 243
K + A+ ++I +LSD Y +DDA +L+ A + T+ S SKTF+M GW
Sbjct: 186 FYKDVIAFAKKHDIIVLSDLAYSEIYFDDAPPPSVLEVPGATDVTVEFTSMSKTFSMPGW 245
Query: 244 RLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKL 303
R+GF V +I + ++ +Y+ + IQVA +AL + S + E+R Y RR +
Sbjct: 246 RMGFAVGNERLIAALTRVKSYLDYGAFTPIQVAATQALNGDGS--DIAEVRAIYKRRRDV 303
Query: 304 VLKRLKEMPGIRVKEPKGAFYVFPSI--KDTGMSSEKFSEWLLEKARVVVIPGTAFGKMG 361
+++ + G V P + + I K + S +FS+ L+EKA V V PG FG+ G
Sbjct: 304 MVESFGK-AGFEVPPPPATMFAWAKIPEKFRHLGSLEFSKLLVEKADVAVAPGIGFGEQG 362
Query: 362 EGYVRISYATSREKLMEAMDRMEKALS 388
+ YVR++ + ++ +A +++ LS
Sbjct: 363 DDYVRLALVENEHRIRQAARNIKRFLS 389
>emb|CAB44334.1| (Y17462) cysteine conjugate beta-lyase [Fugu rubripes]
Length = 419
Score = 169 bits (425), Expect = 4e-41
Identities = 118/394 (29%), Positives = 195/394 (48%), Gaps = 33/394 (8%)
Query: 25 FERASKMENVISLGIGEPDFDTPKNIKEACKRALDEG--WTHYTPNAGIQQLREAVVEYY 82
F + + + ++LG G PDF PK ++EA AL+EG YT G L +++ +++
Sbjct: 21 FTQLAAAYSKVNLGQGFPDFAPPKFVQEAFCHALNEGPMMHQYTRAFGHVPLVKSLAKFF 80
Query: 83 KKFYDVDID-VENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPV 141
+ +ID +E++++T GAY+ + AF++L+ GDEV+I +P F Y K+A +PV
Sbjct: 81 SRVIGHEIDPLEDILVTVGAYQALFSAFQALIYEGDEVIIVEPFFDCYQPMVKMAGGQPV 140
Query: 142 RIPLREENN--------FMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADI 193
IPLR + + ++ P+ L T +T+ +VIN PNNP G E + IAD+
Sbjct: 141 YIPLRPKGDGSVLSSGDWVLSPEXLAGKFTPRTKALVINTPNNPLGKVYKTEELQMIADL 200
Query: 194 AQDYNIYILSDEPYEHFIYDDAKHYPMLKFAP--ENTILANSFSKTFAMTGWRLGFVVAP 251
+++ ++SDE YE YD AKH + E TI S KTF+ TGW++G+ ++
Sbjct: 201 CIKHDVLVISDEVYEWLTYDGAKHVKIASLPGMWERTITIGSGGKTFSATGWKVGWAISS 260
Query: 252 SEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKE----MRKEYNERRKLVLKR 307
IIK M +H + + A+ Q A E E +K L
Sbjct: 261 GHIIKHMKTIHQNTVYHCATPAQEAVARGFEREYEVFGTPESYFQQLPAMLHHKKNKLAS 320
Query: 308 LKEMPGIRVKEPKGAFYV---FPSIK----DTGMSSE----KFSEWLLEKARVVVIPGTA 356
L + G++ P+G +++ F SIK D E +F +WL+++ + IP +A
Sbjct: 321 LLKSVGLKPIMPEGGYFMTADFSSIKVDCDDPSSKDEAKDFRFVKWLIKEKGLATIPVSA 380
Query: 357 F-----GKMGEGYVRISYATSREKLMEAMDRMEK 385
F GK + Y+R + L A + ++K
Sbjct: 381 FYSPEHGKEFDKYIRFCFVKEEATLDAAAEILKK 414
>pir||T37220 probable transaminase (EC 2.6.1.-) SC2H4.04c [similarity] -
Streptomyces coelicolor >gi|3559960|emb|CAA20598.1|
(AL031514) putative aminotransferase [Streptomyces
coelicolor A3(2)]
Length = 402
Score = 165 bits (413), Expect = 9e-40
Identities = 118/383 (30%), Positives = 191/383 (49%), Gaps = 22/383 (5%)
Query: 24 LFERASKME----NVISLGIGEP---DFDTPKNIKEACKRALDEGWTHYTPNAGIQQLRE 76
+ E A+ +E +V+ L G P F+ P+ I + R L YT + GI R
Sbjct: 20 VIEHANALEEAGHSVLRLNTGNPALFGFEAPEEIVQDMIRMLPRAHG-YTDSRGILSARR 78
Query: 77 AVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLA 136
AV + Y+ +++DV++V + G E +A ++LLE GDEVLIP P F + LA
Sbjct: 79 AVAQRYQAL-GLEVDVDDVFLGNGVSELISMAVQALLEDGDEVLIPAPDFPLWTAVTTLA 137
Query: 137 EAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQD 196
K V E+ + PD ++ +T +T+ +VI PNNPTGA KE+ + I D+A+
Sbjct: 138 GGKAVHYLCDEQAEWYPDLADMEAKITDRTKAVVIINPNNPTGAVYPKEIVEGILDLARR 197
Query: 197 YNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILA-NSFSKTFAMTGWRLGFVV--APSE 253
+ + +L+DE Y+ +YDDA H+ AP+ +L SKT+ + G+R G++V P +
Sbjct: 198 HGLMVLADEIYDQILYDDAVHHSAASLAPDLVVLTFCGLSKTYRVAGFRSGWLVVTGPKQ 257
Query: 254 IIKEMIK-----LHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRL 308
++ ++ + N + Q A AL +S + + +E+R + ++L
Sbjct: 258 HARDYLEGLTMLASMRLCANAPA--QYAIQAALGGRQSIRELTAPGGRLHEQRDVAWEKL 315
Query: 309 KEMPGIRVKEPKGAFYVFPSIKDTG---MSSEKFSEWLLEKARVVVIPGTAFGKMGEGYV 365
E+PGI +PKGA Y FP I E+F LL + ++ V+ GT F +
Sbjct: 316 NEIPGISCVKPKGALYAFPRIDPAVHKIHDDERFVLDLLLREKIQVVQGTGFNWPSPDHF 375
Query: 366 RISYATSREKLMEAMDRMEKALS 388
RI E L A+ R+ + LS
Sbjct: 376 RILTLPHAEDLEAAIGRIGRFLS 398
>gi|10954795 aatA gene in Rhizobium leguminosarum homolog~hypothetical
pseudogene(riorf149 and 150 seem to encode one aatA
homolog, which is divided by frame-shift) [Agrobacterium
rhizogenes] >gi|10567459|dbj|BAB16268.1| (AP002086) aatA
gene in Rhizobium leguminosarum homolog~hypothetical
pseudogene(riorf149 and 150 seem to encode one aatA
homolog, which is divided by frame-shift) [Agrobacterium
rhizogenes]
Length = 359
Score = 161 bits (402), Expect = 2e-38
Identities = 86/234 (36%), Positives = 133/234 (56%), Gaps = 7/234 (2%)
Query: 15 LIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQL 74
++ K REL ++ +V+ L IGEPDFDTP NIK A A++ G T YTP +GI +L
Sbjct: 17 IVVSQKFREL---KAEGRDVVRLNIGEPDFDTPDNIKTAAIDAINRGETKYTPVSGIPEL 73
Query: 75 REAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAK 134
R+A+ +K+ ++ E I+ G + + AF + L GDEV+IP P +VSY E
Sbjct: 74 RKAIASKFKRENGLEYSWEQTIVGTGGKQILFNAFMATLNPGDEVVIPAPYWVSYPEMVA 133
Query: 135 LAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIA 194
L PV + +E++F P +L + +T KT+ + N P+NPTGA KA+ ++
Sbjct: 134 LCGGTPVFVSATQEHDFKLQPADLEKAITPKTKWFIFNSPSNPTGAAYTHAELKALTNVL 193
Query: 195 QDY-NIYILSDEPYEHFIYDDAKHYPMLKFAP---ENTILANSFSKTFAMTGWR 244
+ ++++L+D+ YEH Y D K ++ P + T+ N SK +AMTGWR
Sbjct: 194 MQHPHVWVLTDDMYEHLTYSDFKFVTPVEVEPSLYDRTLTMNGVSKAYAMTGWR 247
>sp|O14209|YDT4_SCHPO HYPOTHETICAL AMINOTRANSFERASE C6B12.04C >gi|7492396|pir||T39011
kynurenine--oxoglutarate transaminase (EC 2.6.1.7) /
glutamine--phenylpyruvate transaminase (EC 2.6.1.64)
SPAC6B12.04c [similarity] - fission yeast
(Schizosaccharomyces pombe) >gi|2330836|emb|CAB11066.1|
(Z98531) probable aminotransferase (EC 2.6.1.-)
[Schizosaccharomyces pombe]
Length = 421
Score = 159 bits (398), Expect = 5e-38
Identities = 112/388 (28%), Positives = 186/388 (47%), Gaps = 43/388 (11%)
Query: 35 ISLGIGEPDFDTPKNIKEACKRALDE-GWTHYTPNAGIQQLREAVVEYYKKFYDVDIDVE 93
+SL G +++ PK + +A K+++DE Y+ G LR+A+ E Y ++ ++ +
Sbjct: 35 VSLSQGFFNYNPPKFVLDAAKKSIDEVACNQYSHTRGRPSLRKALSEAYSPYFKRTLNPD 94
Query: 94 N-VIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPL--REENN 150
+++TAGA EG + F + L GDEV++ +P F Y+ + + PV +P+ EE +
Sbjct: 95 TEIVVTAGANEGFFSVFAAFLNPGDEVIVMEPFFDQYISNITMNGGVPVYVPIIPPEEGS 154
Query: 151 FMP--------DPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYIL 202
P D ++L +T+KT+MIVIN P+NP G +E IAD+ +N+ ++
Sbjct: 155 VKPVSAGAWKLDMNKLRNAITEKTKMIVINTPHNPLGKIFSEEELNEIADLVLKHNLLVV 214
Query: 203 SDEPYEHFIYDDAKHYPMLKFA---PE---NTILANSFSKTFAMTGWRLGFVVAPSEIIK 256
SDE +YD P ++ A PE + + S KTF TGWR+G+++ +IK
Sbjct: 215 SDE-----VYDRLSFVPFVRLATLRPELFKHVVTVGSGGKTFGCTGWRVGWLIGDESLIK 269
Query: 257 EMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRV 316
H I V S Q A A E +E + Y +R +++ K ++ I
Sbjct: 270 YSAAAHTRICFAVNSPCQEALAIAFGEAEKHNYYEEYKSSYKKRFEILAKAFDQLE-IPY 328
Query: 317 KEPKGAFYVFPSI------KDTGMSSE--------KFSEWLLEKARVVVIPGTAF----- 357
P G++Y + KD E K W+L++ V IP T F
Sbjct: 329 TIPDGSYYTMANFSKLKLPKDYPFPEEIANRPRDFKLCYWILKEIGVATIPPTEFYTDED 388
Query: 358 GKMGEGYVRISYATSREKLMEAMDRMEK 385
+ E Y+R ++ + E L EA R++K
Sbjct: 389 APVAENYLRFAFCKTFETLEEAARRLQK 416
>sp|Q58786|YD91_METJA PUTATIVE AMINOTRANSFERASE MT1391 >gi|2127837|pir||F64473 D-alanine
transaminase (EC 2.6.1.21) - Methanococcus jannaschii
>gi|1592038|gb|AAB99401.1| (U67579) putative
aminotransferase [Methanococcus jannaschii]
Length = 418
Score = 158 bits (396), Expect = 9e-38
Identities = 112/347 (32%), Positives = 180/347 (51%), Gaps = 16/347 (4%)
Query: 16 IKRSKIRELFERASKMENVISLGIGEPD-FDTPKNIKEACKRALDEGWTHYTPNAGIQQL 74
IKR+K +E +R ME +I +G+GEPD P+ I+ C+ A Y N GIQ+L
Sbjct: 30 IKRAK-QEAMKRHPDME-LIDMGVGEPDEMADPEVIRVLCEEAKKWENRGYADN-GIQEL 86
Query: 75 REAVVEYYKKFYDV-DID-VENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVED 132
++AV Y +K Y V DID V VI + G+ + + GD L+ P +
Sbjct: 87 KDAVPPYMEKVYGVKDIDPVNEVIHSIGSKPALAYITSAFINPGDVCLMTVPGYPVTATH 146
Query: 133 AKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIAD 192
K + +PL EEN+F+PD + + E + K+ +++ +NYPNNPTGA K+ K + D
Sbjct: 147 TKWYGGEVYNLPLLEENDFLPDLESIPEDIKKRAKILYLNYPNNPTGAQATKKFYKEVVD 206
Query: 193 IAQDYNIYILSDEPYEHFIYDDAK-HYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAP 251
A + + ++ D Y +YD + +K A E + +SFSK F MTGWRL F+V
Sbjct: 207 FAFENEVIVVQDAAYGALVYDGKPLSFLSVKDAKEVGVEIHSFSKAFNMTGWRLAFLVGN 266
Query: 252 SEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEM 311
IIK + IQ AG+ L+ E + +R++Y R + ++K L E+
Sbjct: 267 ELIIKAFATVKDNFDSGQFIPIQKAGIYCLQHPE---ITERVRQKYERRLRKMVKILNEV 323
Query: 312 PGIRVKEPKGAFYVF--PSIKDTGM---SSEKFSEWLLEKARVVVIP 353
G + + P G FY++ K G+ ++E FS++L+++ + +P
Sbjct: 324 -GFKARMPGGTFYLYVKSPTKANGIEFKTAEDFSQYLIKEKLISTVP 369
>sp|P77727|YFBQ_ECOLI PROBABLE AMINOTRANSFERASE YFBQ >gi|7447846|pir||H65000 probable
transaminase (EC 2.6.1.-) b2290 [similarity] -
Escherichia coli (strain K-12)
>gi|1788627|gb|AAC75350.1| (AE000318) putative
aminotransferase [Escherichia coli K12]
>gi|1799660|dbj|BAA16127.1| (D90860) ASPARTATE
AMINOTRANSFERASE (EC 2.6.1.1) (TRANSAMINASE A) (ASPAT).
[Escherichia coli]
Length = 405
Score = 156 bits (391), Expect = 3e-37
Identities = 108/366 (29%), Positives = 185/366 (50%), Gaps = 17/366 (4%)
Query: 16 IKRSKIRELFERASKMENVISLGIGEP---DFDTPKNIKEACKRALDEGWTHYTPNAGIQ 72
I+ ++E + V+ L IG P FD P I R L Y + G+
Sbjct: 17 IRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFDAPDEILVDVIRNLPTA-QGYCDSKGLY 75
Query: 73 QLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVED 132
R+A++++Y+ D+ VE++ I G E A ++LL SGDE+L+P P + +
Sbjct: 76 SARKAIMQHYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWTAA 135
Query: 133 AKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIAD 192
L+ K V E +++ PD D++ +T +TR IVI PNNPTGA KE+ I +
Sbjct: 136 VSLSSGKAVHYLCDESSDWFPDLDDIRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVE 195
Query: 193 IAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPE-NTILANSFSKTFAMTGWRLGFVVAP 251
IA+ +N+ I +DE Y+ +YDDA+H+ + AP+ TI N SKT+ + G+R G++V
Sbjct: 196 IARQHNLIIFADEIYDKILYDDAEHHSIAPLAPDLLTITFNGLSKTYRVAGFRQGWMVLN 255
Query: 252 SEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEES----WKAVKEM---RKEYNERRKLV 304
K+ K + + +AS A V A + ++ ++++ E E+R
Sbjct: 256 GP--KKHAKGYIEGLEMLASMRLCANVPAQHAIQTALGGYQSISEFITPGGRLYEQRNRA 313
Query: 305 LKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLE---KARVVVIPGTAFGKMG 361
+ + ++PG+ +P+GA Y+FP I + + +L+ + +V+++ GTAF
Sbjct: 314 WELINDIPGVSCVKPRGALYMFPKIDAKRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPW 373
Query: 362 EGYVRI 367
+ RI
Sbjct: 374 PDHFRI 379
>pir||C70605 probable aspartate transaminase (EC 2.6.1.1) aspB [similarity] -
Mycobacterium tuberculosis (strain H37RV)
>gi|1877296|emb|CAB07140.1| (Z92774) aspB [Mycobacterium
tuberculosis]
Length = 388
Score = 156 bits (391), Expect = 3e-37
Identities = 104/359 (28%), Positives = 167/359 (45%), Gaps = 3/359 (0%)
Query: 26 ERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKF 85
ER ++++L G+P P+ ++ A AL Y+ GI +LR+A+ Y++
Sbjct: 25 ERQRTHGDLVNLSAGQPSAGAPEPVRAAAAAALHLNQLGYSVALGIPELRDAIAADYQRR 84
Query: 86 YDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPL 145
+ + ++ + V+IT G+ G LAF + ++GD V + P + Y + V IP
Sbjct: 85 HGITVEPDAVVITTGSSGGFLLAFLACFDAGDRVAMASPGYPCYRNILSALGCEVVEIPC 144
Query: 146 REENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDE 205
+ F P L E + R +V+ P NPTG + E AIA ++ ++SDE
Sbjct: 145 GPQTRFQPTAQMLAE-IDPPLRGVVVASPANPTGTVIPPEELAAIASWCDASDVRLISDE 203
Query: 206 PYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYI 265
Y +Y A N ++ NSFSK +AMTGWRLG+++ P+ + + + L
Sbjct: 204 VYHGLVYQGAPQTSCAWQTSRNAVVVNSFSKYYAMTGWRLGWLLVPTVLRRAVDCLTGNF 263
Query: 266 IGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYV 325
Q+A V A E + +A + Y R L+L L+ + R+ GAFYV
Sbjct: 264 TICPPVLSQIAAVSAFTPEATAEADGNL-ASYAINRSLLLDGLRRIGIDRLAPTDGAFYV 322
Query: 326 FPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFG-KMGEGYVRISYATSREKLMEAMDRM 383
+ + D S F LL V + PG F G +VRIS+A + EA+ R+
Sbjct: 323 YADVSDFTSDSLAFCSKLLADTGVAIAPGIDFDTARGGSFVRISFAGPSGDIEEALRRI 381
>pir||D72220 probable aspartate transaminase (EC 2.6.1.1) TM1698 [similarity] -
Thermotoga maritima (strain MSB8)
>gi|4982275|gb|AAD36765.1|AE001810_4 (AE001810)
aspartate aminotransferase [Thermotoga maritima]
Length = 397
Score = 155 bits (389), Expect = 6e-37
Identities = 115/393 (29%), Positives = 200/393 (50%), Gaps = 25/393 (6%)
Query: 10 AERVILIKRSKIREL--FERASKMENVI--SLGIGEPDFDTPKNIKEACKRALDEGWTHY 65
++RV+L + S IR+L F +K V L IG+PD TP+ E E +Y
Sbjct: 5 SDRVLLTEESPIRKLVPFAEMAKKRGVRIHHLNIGQPDLKTPEVFFERIYENKPEV-VYY 63
Query: 66 TPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPA 125
+ +AGI +LREA YYK+ VD+ ENV++T G E +F + GDE+L+ +P
Sbjct: 64 SHSAGIWELREAFASYYKRRQRVDVKPENVLVTNGGSEAILFSFAVIANPGDEILVLEPF 123
Query: 126 FVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKE 185
+ +Y AK+A K + + R E F P L + ++T+ IV++ P NPTG K+
Sbjct: 124 YANYNAFAKIAGVKLIPVTRRMEEGF-AIPQNLESFINERTKGIVLSNPCNPTGVVYGKD 182
Query: 186 VAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRL 245
+ + +IA+ + ++++ DE Y ++ + L + ++ +S SK F+ G R+
Sbjct: 183 EMRYLVEIAERHGLFLIVDEVYSEIVF-RGEFASALSIESDKVVVIDSVSKKFSACGARV 241
Query: 246 GFVVAPS-EIIKEMIKLHAYIIGNVASFI--QVAGVEALRSEESWKAVKEMRKEYNERRK 302
G ++ + E+I +KL G +A + Q+ V L ++S+ +R+ Y ER +
Sbjct: 242 GCLITRNEELISHAMKLAQ---GRLAPPLLEQIGSVGLLNLDDSF--FDFVRETYRERVE 296
Query: 303 LVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLL-----EKARVVVIPGTAF 357
VLK+L+E R +P GAFY+ + +E+F+ W+L + +V P F
Sbjct: 297 TVLKKLEEHGLKRFTKPSGAFYITAELPVE--DAEEFARWMLTDFNMDGETTMVAPLRGF 354
Query: 358 ---GKMGEGYVRISYATSREKLMEAMDRMEKAL 387
+G+ +RI+ ++ L A+D + + L
Sbjct: 355 YLTPGLGKKEIRIACVLEKDLLSRAIDVLMEGL 387
>dbj|BAB05914.1| (AP001514) aspartate aminotransferase [Bacillus halodurans]
Length = 403
Score = 155 bits (387), Expect = 1e-36
Identities = 114/399 (28%), Positives = 192/399 (47%), Gaps = 26/399 (6%)
Query: 7 YFIAERVI--LIKRSKIRELFERASKM------ENVISLGIGEPDFDTPKNIKE---ACK 55
Y IA+ + L + S IR++FE ++ ENV +G P D P + E A
Sbjct: 11 YMIAKEIEQNLTQSSWIRKMFEEGQRLKSIHGTENVFDFSLGNPIIDPPASYFEQLRAYA 70
Query: 56 RALDEGWTHYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLES 115
A +G Y PN G+ + R+ V E+ ++ +I + V +T+GA +A +S++
Sbjct: 71 NAPIQGGHSYIPNQGLPEARQKVAEHMNGRFNTNITAQTVTMTSGAAGALNVALKSIMNP 130
Query: 116 GDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPN 175
GDEV+I P F Y A V PL E+ F D +EL + ++ KT+ I++N P+
Sbjct: 131 GDEVIIFTPYFAEYKFYVGNANGVAVYCPLAEDFTF--DFNELEKAISPKTKAIILNNPH 188
Query: 176 NPTGATLDKEVAKAIAD--IAQDY----NIYILSDEPYEHFIYDDAKHYPMLKFAPENTI 229
NPTG + + + + +A++ I++L D+PY IYD P A E
Sbjct: 189 NPTGQLIPQSDLERLNQYLVAKEQEWGTEIHVLYDDPYSQLIYDGNVPNPFA--AIERLF 246
Query: 230 LANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKA 289
+SFSK + G RLG++ + + A++ N A V R
Sbjct: 247 YISSFSKDLGLAGERLGYLAIRPDFPSVEQYMAAFVFANRTLGFGNATVTVQRMISKMDT 306
Query: 290 VKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARV 349
+ + + EY +RR +++ L++ G PKG F++FP K KF + E+ ++
Sbjct: 307 LTQEQHEYKKRRDAMVQVLED-AGFEFVYPKGGFFIFP--KSPIADDTKFCQVAAEEFQL 363
Query: 350 VVIPGTAFGKMGEGYVRISYATSREKLMEAMDRMEKALS 388
+V+PG FG+ G+ R+SY+ S E++ + ++K S
Sbjct: 364 LVVPGIGFGR--AGHFRLSYSVSMEQIERSAPVLKKLKS 400
>pir||B83293 probable aminotransferase PA2828 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9948913|gb|AAG06216.1|AE004709_9 (AE004709) probable
aminotransferase [Pseudomonas aeruginosa]
Length = 403
Score = 152 bits (381), Expect = 5e-36
Identities = 103/363 (28%), Positives = 184/363 (50%), Gaps = 15/363 (4%)
Query: 34 VISLGIGEP---DFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYDVDI 90
++ L IG P F+ P+ I + R L Y+ + G+ R+AV++YY++ +
Sbjct: 34 ILKLNIGNPAPFGFEAPEEILQDVIRNLPTA-QGYSDSKGLFSARKAVMQYYQQKQVEGV 92
Query: 91 DVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENN 150
+E++ + G E ++ ++LL +GDEVLIP P + + LA KPV E+ N
Sbjct: 93 GIEDIYLGNGVSELIVMSMQALLNNGDEVLIPAPDYPLWTAAVSLAGGKPVHYLCDEQAN 152
Query: 151 FMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHF 210
+ PD +++ +T TR +VI PNNPTGA +EV + + ++A+ +N+ + SDE Y+
Sbjct: 153 WWPDLEDIKAKITPNTRAMVIINPNNPTGAVYSREVLEGMVELARQHNLVLFSDEIYDKI 212
Query: 211 IYDDAKHYPMLKFAPENTILA-NSFSKTFAMTGWRLGFVV--APSEIIKEMIKLHAYIIG 267
+YD A H AP+ L N SK++ + G+R G+V P + + I+ I+
Sbjct: 213 LYDGAVHVSTASLAPDVLCLTFNGLSKSYRVAGFRSGWVAISGPKQRAQSYIE-GLDILA 271
Query: 268 NVASFIQVAGVEALRSE-ESWKAVKEM---RKEYNERRKLVLKRLKEMPGIRVKEPKGAF 323
N+ V A+++ ++++ ++ E+R + L ++PG+ +P GA
Sbjct: 272 NMRLCANVPAQHAIQTALGGYQSINDLVLPPGRLLEQRNRAWELLNDIPGVSCVKPMGAL 331
Query: 324 YVFPSIKDTGM---SSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAM 380
Y FP I + EKF LL +++++ GTAF + R+ + L +A+
Sbjct: 332 YAFPRIDPKVCPIHNDEKFVLDLLLSEKLLIVQGTAFNWPWPDHFRVVTLPRVDDLEQAI 391
Query: 381 DRM 383
R+
Sbjct: 392 LRI 394
>pir||S48737 kynurenine aminotransferase - rat >gi|688258|gb|AAB32197.1|
(S74029) kynurenine aminotransferase, glutamine
transaminase K, KAT, GTK [rats, kidney, Peptide, 423 aa]
[Rattus sp.]
Length = 423
Score = 152 bits (380), Expect = 7e-36
Identities = 100/398 (25%), Positives = 192/398 (48%), Gaps = 38/398 (9%)
Query: 25 FERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGW--THYTPNAGIQQLREAVVEYY 82
F + +K +V++LG G PDF P +A ++A + YT G L + ++
Sbjct: 21 FGKLTKEYDVVNLGQGFPDFSPPDFATQAFQQATSGNFMLNQYTRAFGYPPLTNVLASFF 80
Query: 83 KKFYDVDID-VENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPV 141
K ++D + NV++T GAY + AF++L++ GDEV+I +PAF Y +A PV
Sbjct: 81 GKLLGQEMDPLTNVLVTVGAYGALFTAFQALVDEGDEVIIMEPAFDCYEPMTMMAGGCPV 140
Query: 142 RIPLREE----------NNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIA 191
+ L+ N++ DP EL T +T+++V+N PNNP G + + +A
Sbjct: 141 FVTLKPSPAPKGKLGASNDWQLDPAELASKFTPRTKVLVLNTPNNPLGKVFSRMELELVA 200
Query: 192 DIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAP--ENTILANSFSKTFAMTGWRLGFVV 249
++ Q +++ +SDE Y+ +YD +H + + T+ S K+F+ TGW++G+V+
Sbjct: 201 NLCQQHDVVCISDEVYQWLVYDGHQHVSIASLPGMWDRTLTIGSAGKSFSATGWKVGWVM 260
Query: 250 APSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESW-----KAVKEMRKEYNERRKLV 304
P I+K + +H I + + Q A + E+ ++ + R +
Sbjct: 261 GPDNIMKHLRTVHQNSIFHCPTQAQAAVAQCFEREQQHFGQPSSYFLQLPQAMELNRDHM 320
Query: 305 LKRLKEMPGIRVKEPKGAFYVFPSIKD--------TGMSSE----KFSEWLLEKARVVVI 352
++ L+ + G+++ +G++++ I D G E +F++W+++ +V I
Sbjct: 321 IRSLQSV-GLKLWISQGSYFLIADISDFKSKMPDLPGAEDEPYDRRFAKWMIKNMGLVGI 379
Query: 353 PGTAF-----GKMGEGYVRISYATSREKLMEAMDRMEK 385
P + F K + Y+R + + L +R+ K
Sbjct: 380 PVSTFFSRPHQKDFDHYIRFCFVKDKATLQAMDERLRK 417
>gi|4757928 cytoplasmic cysteine conjugate-beta lyase; glutamine transaminase
K; kynurenine aminotransferase; glutamine-phenylpyruvate
transaminase; glutamine-phenylpyruvate aminotransferase
[Homo sapiens] >gi|11427802|ref|XP_005366.1| cysteine
conjugate-beta lyase; cytoplasmic (glutamine
transaminase K, kyneurenine aminotransferase) [Homo
sapiens] >gi|1082403|pir||S52790
kynurenine--oxoglutarate transaminase (EC 2.6.1.7) /
glutamine--phenylpyruvate transaminase (EC 2.6.1.64),
cytosolic [similarity] - human >gi|2146953|pir||S69001
glutamine--phenylpyruvate aminotransferase (EC 2.6.1.64)
- human >gi|758591|emb|CAA57702.1| (X82224)
glutamine--phenylpyruvate aminotransferase [Homo
sapiens]
Length = 422
Score = 152 bits (380), Expect = 7e-36
Identities = 102/394 (25%), Positives = 189/394 (47%), Gaps = 39/394 (9%)
Query: 25 FERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGW--THYTPNAGIQQLREAVVEYY 82
F + + +V++LG G PDF P EA + A+ + YT G L + + ++
Sbjct: 21 FVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFF 80
Query: 83 KKFYDVDID-VENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPV 141
+ +ID + NV++T G Y + AF++L++ GDEV+I +P F Y +A +PV
Sbjct: 81 GELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPV 140
Query: 142 RIPLR----------EENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIA 191
+ L+ +N+ DP EL T +T+ +V+N PNNP G +E + +A
Sbjct: 141 FVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVA 200
Query: 192 DIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAP--ENTILANSFSKTFAMTGWRLGFVV 249
+ Q +++ ++DE Y+ +YD +H + E T+ S KTF+ TGW++G+V+
Sbjct: 201 SLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVL 260
Query: 250 APSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSE-----ESWKAVKEMRKEYNERRKLV 304
P I+K + +H + + + Q A E+ E + + + R +
Sbjct: 261 GPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHM 320
Query: 305 LKRLKEMPGIRVKEPKGAFYVFPSIKD--------TGMSSE----KFSEWLLEKARVVVI 352
++ L+ + G++ P+G++++ I D G E +F +W+++ +V I
Sbjct: 321 IRSLQSV-GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAI 379
Query: 353 PGTAF-----GKMGEGYVRISYATSREKLMEAMD 381
P + F K + Y+R + E ++AMD
Sbjct: 380 PVSIFYSVPHQKHFDHYIRFCFVKD-EATLQAMD 412
>gb|AAF06837.1|AF100154_1 (AF100154) kynurenine aminotransferase/glutamine transaminase K
[Rattus norvegicus]
Length = 457
Score = 152 bits (380), Expect = 7e-36
Identities = 100/398 (25%), Positives = 192/398 (48%), Gaps = 38/398 (9%)
Query: 25 FERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGW--THYTPNAGIQQLREAVVEYY 82
F + +K +V++LG G PDF P +A ++A + YT G L + ++
Sbjct: 55 FGKLTKEYDVVNLGQGFPDFSPPDFATQAFQQATSGNFMLNQYTRAFGYPPLTNVLASFF 114
Query: 83 KKFYDVDID-VENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPV 141
K ++D + NV++T GAY + AF++L++ GDEV+I +PAF Y +A PV
Sbjct: 115 GKLLGQEMDPLTNVLVTVGAYGALFTAFQALVDEGDEVIIMEPAFDCYEPMTMMAGGCPV 174
Query: 142 RIPLREE----------NNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIA 191
+ L+ N++ DP EL T +T+++V+N PNNP G + + +A
Sbjct: 175 FVTLKPSPAPKGKLGASNDWQLDPAELASKFTPRTKILVLNTPNNPLGKVFSRMELELVA 234
Query: 192 DIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAP--ENTILANSFSKTFAMTGWRLGFVV 249
++ Q +++ +SDE Y+ +YD +H + + T+ S K+F+ TGW++G+V+
Sbjct: 235 NLCQQHDVVCISDEVYQWLVYDGHQHVSIASLPGMWDRTLTIGSAGKSFSATGWKVGWVM 294
Query: 250 APSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESW-----KAVKEMRKEYNERRKLV 304
P I+K + +H I + + Q A + E+ ++ + R +
Sbjct: 295 GPDNIMKHLRTVHQNSIFHCPTQAQAAVAQCFEREQQHFGQPSSYFLQLPQAMELNRDHM 354
Query: 305 LKRLKEMPGIRVKEPKGAFYVFPSIKD--------TGMSSE----KFSEWLLEKARVVVI 352
++ L+ + G+++ +G++++ I D G E +F++W+++ +V I
Sbjct: 355 IRSLQSV-GLKLWISQGSYFLIADISDFKSKMPDLPGAEDEPYDRRFAKWMIKNMGLVGI 413
Query: 353 PGTAF-----GKMGEGYVRISYATSREKLMEAMDRMEK 385
P + F K + Y+R + + L +R+ K
Sbjct: 414 PVSTFFSRPHQKDFDHYIRFCFVKDKATLQAMDERLRK 451
>pir||S75949 probable aspartate transaminase (EC 2.6.1.1) aspC slr0036
[similarity] - Synechocystis sp. (strain PCC 6803)
>gi|1001309|dbj|BAA10796.1| (D64006) aspartate
aminotransferase [Synechocystis sp.]
Length = 389
Score = 152 bits (379), Expect = 9e-36
Identities = 105/367 (28%), Positives = 192/367 (51%), Gaps = 21/367 (5%)
Query: 35 ISLGIGEPDFDTPKNIKEACKRALDEGWTH-YTPNAGIQQLREAVVEYYKKFYDVDIDVE 93
ISLG G + P + A + +L++ H Y P AGI L A+ E ++ D+++ +
Sbjct: 32 ISLGQGVAFYPPPNEVAVAVRESLEQTPLHQYQPVAGIPSLISALTEKLRRDNDINLSSD 91
Query: 94 N-VIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENNFM 152
V++TAGA G A ++ E GDE+++ P + ++ ++A +PV +P ++ +
Sbjct: 92 QAVVVTAGANMGFLNAVLAITEVGDEIILNTPYYFNHEMAVRIAGCQPVLVPT--DDQYQ 149
Query: 153 PDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHFIY 212
D + + + +TR +V PNNPTGA + +A+ + Q+ IY + DE Y++F Y
Sbjct: 150 LQLDLIAQAIAPRTRAVVTISPNNPTGAIYPEADLRAVNQLCQERGIYHIHDEAYDYFAY 209
Query: 213 DDAKHYPMLKFAPE-------NTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYI 265
D P+ F+PE +TI SFSK + M GWR+G++V P E++ + K+
Sbjct: 210 DQT---PI--FSPEAMGDSGGHTISLYSFSKAYGMAGWRVGYMVIPLELLLAVKKIQDTN 264
Query: 266 IGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPG-IRVKEPKGAFY 324
+ Q A + LR +++ A + E R+ +L+ L ++ R+ P+GAFY
Sbjct: 265 LICPVVVSQYAALACLRVGKNYSA--QFLPEMAACRQQLLETLGQLSDYCRLVVPQGAFY 322
Query: 325 VFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLME-AMDRM 383
+ ++ ++ + + L+++ +V V+PG+ FG Y+RI+Y R+ A+ R+
Sbjct: 323 CLLEV-NSPLTDLELVKRLIDEFKVAVLPGSTFGVDSGCYLRIAYGALRQATASVAIARL 381
Query: 384 EKALSEL 390
E+ L +
Sbjct: 382 EQGLKSI 388
>pir||H69826 aspartate aminotransferase homolog yhdR - Bacillus subtilis
>gi|2226213|emb|CAA74502.1| (Y14082) hypothetical
protein [Bacillus subtilis] >gi|2633292|emb|CAB12796.1|
(Z99109) similar to aspartate aminotransferase [Bacillus
subtilis]
Length = 393
Score = 152 bits (379), Expect = 9e-36
Identities = 104/379 (27%), Positives = 181/379 (47%), Gaps = 21/379 (5%)
Query: 15 LIKRSKIRELFERASKM------ENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPN 68
L K S IR+LF+ +++ + V +G P + P+ K A ++G Y N
Sbjct: 14 LNKGSWIRKLFDEGARLKKEFGEDQVFDFSLGNPIVEPPEAFKRALIEEAEKGSHGYIQN 73
Query: 69 AGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVS 128
G+ RE V ++ ++ D E +++T GA +A +S++ G+EV+I P F
Sbjct: 74 QGLLAAREKVAQFLGSRFEADFSAERIVMTVGAGGALNVALKSIVNPGEEVIILAPYFAE 133
Query: 129 YVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAK 188
Y + K V PL + F D + + + +T +T+ +++N P+NPTG L ++
Sbjct: 134 YKLYIENYGGKAVSCPL--TSRFEIDIEAVRQSITPQTKGLILNTPHNPTGTVLSQKNID 191
Query: 189 AIADIAQD------YNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTG 242
+ + ++ IY+L DEPY IYD+ P + ILA+SFSK + G
Sbjct: 192 DLGALLKEIEEKSGQTIYVLFDEPYSQLIYDEELANPFQSY--HRVILASSFSKDLGIAG 249
Query: 243 WRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRK 302
RLG++ S + + ++A++ N A V R+ ++ Y ERR
Sbjct: 250 ERLGYIGLDSRMPDADLLINAFVYCNRTLGFVNAPVMMQRAVARMDDLRVDASAYKERRD 309
Query: 303 LVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGE 362
L++ LKE G + PKG F+VFP K F +K +++++P + FG
Sbjct: 310 LMVDILKE-AGFEFEMPKGGFFVFP--KSPIEDEVAFCVHAAQKYKLLIVPSSGFGM--S 364
Query: 363 GYVRISYATSREKLMEAMD 381
G+ R+S++ E++ + D
Sbjct: 365 GHFRLSFSVPIEQIKNSRD 383
>pir||I57944 cysteine conjugate beta-lyase - rat >gi|300516|gb|AAB26845.1|
(S61960) cysteine conjugate beta-lyase [rats, kidney,
Peptide, 423 aa] [Rattus sp.]
Length = 423
Score = 150 bits (375), Expect = 3e-35
Identities = 99/398 (24%), Positives = 191/398 (47%), Gaps = 38/398 (9%)
Query: 25 FERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGW--THYTPNAGIQQLREAVVEYY 82
F + +K +V++LG G PDF P +A ++A + YT G L + ++
Sbjct: 21 FGKLTKEYDVVNLGQGFPDFSPPDFATQAFQQATSGNFMLNQYTRAFGYPPLTNVLASFF 80
Query: 83 KKFYDVDID-VENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPV 141
K ++D + NV++T GAY + F++L++ GDEV+I +PAF Y +A PV
Sbjct: 81 GKLLGQEMDPLTNVLVTVGAYGALFTRFQALVDEGDEVIIMEPAFDCYEPMTMMAGGCPV 140
Query: 142 RIPLREE----------NNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIA 191
+ L+ N++ DP EL T +T+++V+N PNNP G + + +A
Sbjct: 141 FVTLKPSPAPKGKLGASNDWQLDPAELASKFTPRTKILVLNTPNNPLGKVFSRMELELVA 200
Query: 192 DIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAP--ENTILANSFSKTFAMTGWRLGFVV 249
++ Q +++ +SDE Y+ +YD +H + + T+ S K+F+ TGW++G+V+
Sbjct: 201 NLCQQHDVVCISDEVYQWLVYDGHQHVSIASLPGMWDRTLTIGSAGKSFSATGWKVGWVM 260
Query: 250 APSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESW-----KAVKEMRKEYNERRKLV 304
P I+K + +H I + + Q A + E+ ++ + R +
Sbjct: 261 GPDNIMKHLRTVHQNSIFHCPTQAQAAVAQCFEREQQHFGQPSSYFLQLPQAMELNRDHM 320
Query: 305 LKRLKEMPGIRVKEPKGAFYVFPSIKD--------TGMSSE----KFSEWLLEKARVVVI 352
++ L+ + G+++ +G++++ I D G E +F++W+++ +V I
Sbjct: 321 IRSLQSV-GLKLWISQGSYFLIADISDFKSKMPDLPGAEDEPYDRRFAKWMIKNMGLVGI 379
Query: 353 PGTAF-----GKMGEGYVRISYATSREKLMEAMDRMEK 385
P + F K + Y+R + + L +R+ K
Sbjct: 380 PVSTFFSRPHQKDFDHYIRFCFVKDKATLQAMDERLRK 417
>pir||S66270 kynurenine--oxoglutarate transaminase (EC 2.6.1.7) /
glutamine--phenylpyruvate transaminase (EC 2.6.1.64)
mitochondrial precursor [validated] - rat
>gi|1030066|emb|CAA89696.1| (Z49696) kynurenine
aminotransferase/glutamine transaminase K [Rattus
rattus]
Length = 457
Score = 150 bits (375), Expect = 3e-35
Identities = 99/398 (24%), Positives = 191/398 (47%), Gaps = 38/398 (9%)
Query: 25 FERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGW--THYTPNAGIQQLREAVVEYY 82
F + +K +V++LG G PDF P +A ++A + YT G L + ++
Sbjct: 55 FGKLTKEYDVVNLGQGFPDFSPPDFATQAFQQATSGNFMLNQYTRAFGYPPLTNVLASFF 114
Query: 83 KKFYDVDID-VENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPV 141
K ++D + NV++T GAY + F++L++ GDEV+I +PAF Y +A PV
Sbjct: 115 GKLLGQEMDPLTNVLVTVGAYGALFTRFQALVDEGDEVIIMEPAFDCYEPMTMMAGGCPV 174
Query: 142 RIPLREE----------NNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIA 191
+ L+ N++ DP EL T +T+++V+N PNNP G + + +A
Sbjct: 175 FVTLKPSPAPKGKLGASNDWQLDPAELASKFTPRTKILVLNTPNNPLGKVFSRMELELVA 234
Query: 192 DIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAP--ENTILANSFSKTFAMTGWRLGFVV 249
++ Q +++ +SDE Y+ +YD +H + + T+ S K+F+ TGW++G+V+
Sbjct: 235 NLCQQHDVVCISDEVYQWLVYDGHQHVSIASLPGMWDRTLTIGSAGKSFSATGWKVGWVM 294
Query: 250 APSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESW-----KAVKEMRKEYNERRKLV 304
P I+K + +H I + + Q A + E+ ++ + R +
Sbjct: 295 GPDNIMKHLRTVHQNSIFHCPTQAQAAVAQCFEREQQHFGQPSSYFLQLPQAMELNRDHM 354
Query: 305 LKRLKEMPGIRVKEPKGAFYVFPSIKD--------TGMSSE----KFSEWLLEKARVVVI 352
++ L+ + G+++ +G++++ I D G E +F++W+++ +V I
Sbjct: 355 IRSLQSV-GLKLWISQGSYFLIADISDFKSKMPDLPGAEDEPYDRRFAKWMIKNMGLVGI 413
Query: 353 PGTAF-----GKMGEGYVRISYATSREKLMEAMDRMEK 385
P + F K + Y+R + + L +R+ K
Sbjct: 414 PVSTFFSRPHQKDFDHYIRFCFVKDKATLQAMDERLRK 451
>pir||S74724 aspartate transaminase (EC 2.6.1.1) - Synechocystis sp. (strain
PCC 6803) >gi|1651949|dbj|BAA16875.1| (D90901) aspartate
transaminase [Synechocystis sp.]
Length = 391
Score = 149 bits (372), Expect = 6e-35
Identities = 101/364 (27%), Positives = 182/364 (49%), Gaps = 9/364 (2%)
Query: 32 ENVISLGIGEPDFDTPKNIKEACKRALDEGWTH-YTPNAGIQQLREAVVEYYKKFYDVDI 90
+ +I L +G D TP I +AL++ TH Y + G LR+A+ +Y+K + + +
Sbjct: 30 QTIIDLSLGSSDLPTPAPILATIAKALEDPSTHGYLLHQGTLPLRQAIAVWYEKRFGLAV 89
Query: 91 DVENVIITA-GAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREEN 149
D E ++ G+ EGT ++L GD L+ DP + S++ LA + + LR EN
Sbjct: 90 DAETEVLPLIGSQEGTAHLPLAVLNPGDVALLMDPGYPSHMGGVYLAGGEIYPMALRSEN 149
Query: 150 NFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEH 209
F+P + V K +M V++YP+NPT A E + +D+++ ++ D PY
Sbjct: 150 QFLPVFTAIPNSVLAKAKMTVLSYPHNPTTAIASLEFFQTAVQFCRDHDLVLVHDFPYMD 209
Query: 210 FIYDDAKHYPMLKFAPENTILA---NSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYII 266
++D P + A A +FSK++ M G+R+GF + ++I + K+ A +
Sbjct: 210 LVFDGIAMPPSVLQADRQKSCAIEFFTFSKSYNMGGFRIGFAIGNIQLISALKKIKAVVD 269
Query: 267 GNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVF 326
N + I + AL S + V++ + + +RR ++ L ++ G V P YV+
Sbjct: 270 FNQYAGILQGAIAALESPP--ETVQQTVQIFAQRRATLIDALAKI-GWAVPLPTATMYVW 326
Query: 327 PSIKDTGM-SSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAMDRMEK 385
+ ++ + +S +F + L+ K V + PG+ FG GEGYVR + + L A ++ +
Sbjct: 327 APLPESWLGNSLEFCQKLVAKTGVALSPGSGFGAGGEGYVRFALVQEPDILATAAKKIGQ 386
Query: 386 ALSE 389
L +
Sbjct: 387 FLDQ 390
>pir||H82131 probable aspartate aminotransferase VC1977 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9656518|gb|AAF95125.1| (AE004273) aspartate
aminotransferase, putative [Vibrio cholerae]
Length = 404
Score = 149 bits (372), Expect = 6e-35
Identities = 117/388 (30%), Positives = 190/388 (48%), Gaps = 31/388 (7%)
Query: 24 LFERASKMEN----VISLGIGEP---DFDTPKNIKEACKRALDEGWTHYTPNAGIQQLRE 76
+ + A +ME ++ L IG P FD P I R L Y + GI R+
Sbjct: 21 VLKHAKRMEEEGHKILKLNIGNPAPFGFDAPDEILVDVIRNLPTS-QGYCDSKGIYSARK 79
Query: 77 AVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLA 136
AVV+YY+K +DVE+V I GA E +A ++LL +GDE+L+P P + + L+
Sbjct: 80 AVVQYYQKKGIRSLDVEDVYIGNGASELIVMAMQALLNNGDEMLVPAPDYPLWTAAVALS 139
Query: 137 EAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQD 196
K V EE ++ PD D++ +T KTR IV+ PNNPTGA ++ I +IA+
Sbjct: 140 GGKAVHYICDEEADWYPDLDDIRSKITPKTRGIVLINPNNPTGAVYSRDFLLEIIEIARK 199
Query: 197 YNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILA-NSFSKTFAMTGWRLG--FVVAPSE 253
+ + I +DE Y+ +YD A H + A + ++ N SK + + G+R G F+ P +
Sbjct: 200 HKLMIFADEIYDKVLYDGAVHTSIATLADDVLVVTFNGLSKAYRVCGFRGGWMFLTGPKQ 259
Query: 254 IIKEMIKLHAYIIG--NVASFIQVAGVEALRSEES----WKAVKEM---RKEYNERRKLV 304
+ YI G +AS A V + ++ ++++ E+ E+R
Sbjct: 260 ------QAQGYIAGLDMLASMRLCANVPMQHAIQTALGGYQSINELILPGGRLLEQRDRA 313
Query: 305 LKRLKEMPGIRVKEPKGAFYVFPSIKDTGM----SSEKFSEWLLEKARVVVIPGTAFGKM 360
+ + ++PGI +PKGA Y+FP I DT M +K L + +V+++ G+ F
Sbjct: 314 WELINQIPGISCVKPKGAMYLFPKI-DTKMYPIKDDQKMVLDFLVQEKVLLVQGSGFNWP 372
Query: 361 GEGYVRISYATSREKLMEAMDRMEKALS 388
+ RI E L A+ R E+ ++
Sbjct: 373 KPDHFRIVTLPHVEDLEIAISRFERFIT 400
>dbj|BAA75925.1| (AB012002) aspartate aminotransferase [Pyrococcus kodakaraensis]
Length = 364
Score = 148 bits (369), Expect = 1e-34
Identities = 103/348 (29%), Positives = 171/348 (48%), Gaps = 29/348 (8%)
Query: 21 IRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVE 80
+ E F R +++ L G+PD + I E +L G T YT GI++LRE + E
Sbjct: 4 VYEFFNRINEVRPESRLDAGQPDIPVRREIIEEAVESLRRGETGYTSTGGIRELRERIAE 63
Query: 81 YYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKP 140
+ + + VI+ GA + + + S +V + P + +Y A+ +
Sbjct: 64 FE------GVSADEVIVAPGAK----ILIAAEIASAKKVAVVSPRWNAYSLIARQFWREV 113
Query: 141 VRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIY 200
I + ++P +E+ K +I+INYPNNPTG L + + + D+A++ +
Sbjct: 114 EVIKTTLDERWIPRVEEI------KADLIIINYPNNPTGRVLSGKEIRGLLDVAEENGVK 167
Query: 201 ILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIK 260
+LSDE Y + + + EN + FSK ++MTG+RLG+ + I+ + +
Sbjct: 168 VLSDEVYAELSF---TRFTPARELYENVVTVKGFSKLYSMTGFRLGYAIGERNEIRRIQR 224
Query: 261 LHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPK 320
+ V F+Q AGV+AL + + +KE+R+ Y ER ++ K L+ G EP+
Sbjct: 225 FIESTVTCVPPFVQRAGVKALELRD--ELIKEVRRAYLERVRMASKMLR---GFDFVEPE 279
Query: 321 GAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRIS 368
GAFY+F GM+ F+E LL + V V PG AFG ++RIS
Sbjct: 280 GAFYIFLRTPQDGMA---FAERLLSRG-VAVFPGMAFGDY-PNFIRIS 322
>sp|P71348|YFBQ_HAEIN PROBABLE AMINOTRANSFERASE HI0286 >gi|1573250|gb|AAC21948.1|
(U32714) aminotransferase [Haemophilus influenzae Rd]
Length = 404
Score = 147 bits (368), Expect = 2e-34
Identities = 110/382 (28%), Positives = 181/382 (46%), Gaps = 17/382 (4%)
Query: 22 RELFERASKMENVISLGIGEP---DFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAV 78
+E + ++ L IG P F+ P I R L Y + G+ R+A+
Sbjct: 23 KEALRLEEEGNKILKLNIGNPAPFGFEAPDEILVDVLRNLPSA-QGYCDSKGLYSARKAI 81
Query: 79 VEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEA 138
V+YY+ + V +V I G E +A ++LL GDEVL+P P + + L+
Sbjct: 82 VQYYQSKGILGATVNDVYIGNGVSELITMAMQALLNDGDEVLVPMPDYPLWTAAVTLSGG 141
Query: 139 KPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYN 198
K V E+ N+ P D++ V KT+ IVI PNNPTGA KE+ + I +IA+ N
Sbjct: 142 KAVHYLCDEDANWFPTIDDIKAKVNAKTKAIVIINPNNPTGAVYSKELLQEIVEIARQNN 201
Query: 199 IYILSDEPYEHFIYDDAKHYPMLKFAPE-NTILANSFSKTFAMTGWRLGFVVAPSEIIKE 257
+ I +DE Y+ +YD A H+ + AP+ T+ N SK + + G+R G+++ K
Sbjct: 202 LIIFADEIYDKILYDGAVHHHIAALAPDLLTVTLNGLSKAYRVAGFRQGWMILNGP--KH 259
Query: 258 MIKLHAYIIGNVASFIQVAGVEALRSEES----WKAVKEM---RKEYNERRKLVLKRLKE 310
K + + +AS A V + ++ ++++ E E+R + +
Sbjct: 260 NAKGYIEGLDMLASMRLCANVPMQHAIQTALGGYQSINEFILPGGRLLEQRNKAYDLITQ 319
Query: 311 MPGIRVKEPKGAFYVFPSI---KDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRI 367
+PGI +P GA Y+FP I K S EK LL + +V+++ G F + RI
Sbjct: 320 IPGITCVKPMGAMYMFPKIDVKKFNIHSDEKMVLDLLRQEKVLLVHGKGFNWHSPDHFRI 379
Query: 368 SYATSREKLMEAMDRMEKALSE 389
+L EA+ ++ + LS+
Sbjct: 380 VTLPYVNQLEEAITKLARFLSD 401
>pir||T23861 kynurenine--oxoglutarate transaminase (EC 2.6.1.7) /
glutamine--phenylpyruvate transaminase (EC 2.6.1.64),
mitochondrial R03A10.4 [similarity] - Caenorhabditis
elegans >gi|3878875|emb|CAA93673.1| (Z69793) Similarity
to Human glutamine-phenylpyruvate transaminase (PIR Acc.
No. S52790), contains similarity to Pfam domain: PF00155
(Aminotransferases class-I), Score=66.3,
E-value=2.1e-16, N=1~cDNA EST yk74a11.3 comes from this
gene~cDNA EST yk74a11>
Length = 418
Score = 147 bits (368), Expect = 2e-34
Identities = 105/378 (27%), Positives = 173/378 (44%), Gaps = 41/378 (10%)
Query: 35 ISLGIGEPDFDTPKNIKEACKRALDE----GWTHYTPNAGIQQLREAVVEYYKKFYDVDI 90
++LG G PD PK + + + YT G L + + + Y FY+V +
Sbjct: 51 VNLGQGFPDSPAPKFVTDLLENLSKHPELTAAHQYTRGYGHPMLVDILAKMYSHFYNVQV 110
Query: 91 DVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLR--- 146
D N V++T GAY Y AF + GDEVLI +PA+ Y K A PV + +
Sbjct: 111 DPMNEVLVTVGAYLSLYYAFLGWVNKGDEVLIIEPAYDCYYPQVKFAGGVPVPVVMNLAE 170
Query: 147 ---EENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILS 203
+ F D ++ + +KT+M+VIN P+NPTG + + +A+IA+ +N+ +++
Sbjct: 171 GATSASQFTIDFADMESKINEKTKMLVINNPHNPTGKLFSRHELEKLAEIAKKHNLIVIA 230
Query: 204 DEPYEHFIYD--DAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKL 261
DE YE ++D D + L E TI S K F++TGW+LG+ V P ++++ + +
Sbjct: 231 DEVYEFHVWDKNDMVRFASLPGMYERTISIGSAGKAFSVTGWKLGWAVGPKQLLEPLKAI 290
Query: 262 HAYIIGNVASFIQVAGVEALRSE--------ESWKAVKEMRKEYNERRKLVLKRLKEMPG 313
H + ++ Q+A EA R + E+ + E +R + K L+E
Sbjct: 291 HQNCVFTCSTPTQMAIAEAFRLDWPKFLSDPENSYLATGLSGELRAKRDKLAKMLEEGIN 350
Query: 314 IRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGK------MGEGYVRI 367
+ +E F FS WL + ++ VIP +AF VR+
Sbjct: 351 LPTEEDPDDFV--------------FSRWLCREKKLAVIPPSAFYSARDNKLKNSNMVRL 396
Query: 368 SYATSREKLMEAMDRMEK 385
Y E L A + ++K
Sbjct: 397 CYFKKDETLDAAEEILKK 414
>emb|CAA07075.1| (AJ006517) putative aminotransferase [Streptomyces anulatus]
>gi|3550622|emb|CAA06435.1| (AJ005198) StgA protein
[Streptomyces anulatus]
Length = 402
Score = 147 bits (367), Expect = 2e-34
Identities = 109/383 (28%), Positives = 187/383 (48%), Gaps = 24/383 (6%)
Query: 24 LFERASKME----NVISLGIGEP---DFDTPKNIKEACKRALDEGWTHYTPNAGIQQLRE 76
+ E A+ +E +V+ L G P F+ P+ I + R L + YT + G+ R
Sbjct: 20 VIEHANALEEAGHSVLRLNTGNPALFGFEAPEEIVQDMIRMLPQAHG-YTDSRGVLSARR 78
Query: 77 AVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLA 136
AV + Y+ ++ V++V + G E +A ++LLE GDE+LIP P F + L+
Sbjct: 79 AVAQRYQALGLDEVSVDDVFLGNGVSELVTMAVQALLEDGDEILIPAPDFPLWTAVTTLS 138
Query: 137 EAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQD 196
K V E ++ PD D++ +T +T+ + I NPTGA KE+ + I D+A+
Sbjct: 139 GGKAVHYVCDEAADWYPDLDDMASKITDQTKAVEI---INPTGAVYPKEILEGILDLARR 195
Query: 197 YNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILA-NSFSKTFAMTGWRLGFVV--APSE 253
+ + + +DE Y+ +YDDA H+ + AP+ +L SKT+ + G+R G++V P +
Sbjct: 196 HGLMVFADEIYDQILYDDAVHHSVAALAPDLVVLTFCGLSKTYRVAGFRSGWLVITGPRQ 255
Query: 254 IIKEMIK-----LHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRL 308
++ ++ + N + Q A AL +S + + +E+R ++L
Sbjct: 256 HARDYLEGLTMLASMRLCPNAPA--QFAIQAALGGRQSIRELTAPGGALHEQRDRAWEKL 313
Query: 309 KEMPGIRVKEPKGAFYVFPSIKDTG---MSSEKFSEWLLEKARVVVIPGTAFGKMGEGYV 365
E+PG+ +PKGA Y FP + EKF LL + ++ V+ GT F +
Sbjct: 314 NEIPGVSCVKPKGALYAFPRLDPKVHPIHDDEKFVLDLLLQEKIQVVQGTGFNWPRPDHF 373
Query: 366 RISYATSREKLMEAMDRMEKALS 388
RI + L A+ R+ + LS
Sbjct: 374 RILTLPHADDLDAAISRIGRFLS 396
>pir||G81863 probable aminotransferase (EC 2.6.1.-) NMA1684 [imported] -
Neisseria meningitidis (group A strain Z2491)
>gi|7380325|emb|CAB84912.1| (AL162756) probable
aminotransferase [Neisseria meningitidis Z2491]
Length = 404
Score = 146 bits (366), Expect = 3e-34
Identities = 112/389 (28%), Positives = 185/389 (46%), Gaps = 34/389 (8%)
Query: 20 KIRELFERASKMENVISLGIGEP---DFDTPKNIKEACKRALDEGWTHYTPNAGIQQLRE 76
K +L E +K ++ L IG P F+ P I R L Y + G+ R+
Sbjct: 24 KALQLEEEGNK---ILKLNIGNPAPFGFEAPDEILVDVIRNLPTS-QGYCDSKGLYSARK 79
Query: 77 AVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLA 136
A+V YY+ DI V++V I G E ++ ++LL+ GDE+LIP P + + A LA
Sbjct: 80 AIVHYYQTKGLRDITVDDVYIGNGVSELITMSMQALLDDGDEILIPAPDYPLWTAAATLA 139
Query: 137 EAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQD 196
EEN + P+ ++ +T KT+ IV+ PNNPTGA +E+ IA++A+
Sbjct: 140 GGTVRHYLCDEENGWFPNLADMEAKITPKTKAIVVINPNNPTGAVYSREILLEIAELARK 199
Query: 197 YNIYILSDEPYEHFIYDDAKHYPMLKFAPE-NTILANSFSKTFAMTGWRLGFVVAPSEII 255
+ + I +DE Y+ +YD A H+ + AP+ T+ N SK++ + G+R G++V
Sbjct: 200 HGLIIFADEIYDKILYDGAVHHHIAALAPDLLTVTFNGLSKSYRVAGFRQGWMVLNGP-- 257
Query: 256 KEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYN-------------ERRK 302
K HA G + ++ + + A++ Y E+R
Sbjct: 258 ----KHHAK--GYIEGLDMLSSMRLCANTPMQHAIQTALGGYQSINEFILPGGRLLEQRN 311
Query: 303 LVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGM----SSEKFSEWLLEKARVVVIPGTAFG 358
+ + ++PG+ +P GA Y+FP I DT M KF LL + +V+++ GT F
Sbjct: 312 RAWELVSQIPGVSCVKPMGAMYMFPKI-DTEMYRIRDDMKFVYDLLVREKVLLVQGTGFN 370
Query: 359 KMGEGYVRISYATSREKLMEAMDRMEKAL 387
+ + RI ++ EAM R+ + L
Sbjct: 371 WIKPDHFRIVTLPYVHQIEEAMGRLARFL 399
>gi|6322401 Yjl060wp [Saccharomyces cerevisiae]
>gi|1176356|sp|P47039|YJG0_YEAST HYPOTHETICAL
AMINOTRANSFERASE YJL060W >gi|1078066|pir||S56832
kynurenine--oxoglutarate transaminase (EC 2.6.1.7) /
glutamine--phenylpyruvate transaminase (EC 2.6.1.64)
[similarity] - yeast (Saccharomyces cerevisiae)
>gi|1008205|emb|CAA89351.1| (Z49335) ORF YJL060w
[Saccharomyces cerevisiae]
Length = 444
Score = 146 bits (366), Expect = 3e-34
Identities = 102/385 (26%), Positives = 182/385 (46%), Gaps = 36/385 (9%)
Query: 34 VISLGIGEPDFDTPKNIKEACKRALDEGWTH-YTPNAGIQQLREAVVEYYKKFYDVDIDV 92
+I+LG G + P+ + ++ALD + Y+P G L ++++ Y Y+ ++
Sbjct: 56 LINLGQGFFSYSPPQFAIKEAQKALDIPMVNQYSPTRGRPSLINSLIKLYSPIYNTELKA 115
Query: 93 ENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLR-----E 147
ENV +T GA EG LL +GDEV++ +P F Y+ + +L K V +P+ +
Sbjct: 116 ENVTVTTGANEGILSCLMGLLNAGDEVIVFEPFFDQYIPNIELCGGKVVYVPINPPKELD 175
Query: 148 ENN-----FMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYIL 202
+ N + D ++ + +T KT+ ++IN P+NP G +E + +I +N+ I+
Sbjct: 176 QRNTRGEEWTIDFEQFEKAITSKTKAVIINTPHNPIGKVFTREELTTLGNICVKHNVVII 235
Query: 203 SDEPYEHFIYDDAKHYPMLKFAPE---NTILANSFSKTFAMTGWRLGFVVA-PSEIIKEM 258
SDE YEH + D+ + +PE T+ S K+FA TGWR+G+V++ +E++
Sbjct: 236 SDEVYEHLYFTDS-FTRIATLSPEIGQLTLTVGSAGKSFAATGWRIGWVLSLNAELLSYA 294
Query: 259 IKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKE 318
K H I S +Q A ++ ++MR+EY + K+ E+ G+
Sbjct: 295 AKAHTRICFASPSPLQEACANSINDALKIGYFEKMRQEYINKFKIFTSIFDEL-GLPYTA 353
Query: 319 PKGAFYVFPSIKDTGMSSE--------------KFSEWLLEKARVVVIPGTAF-----GK 359
P+G ++V + + + S WL+ + VV IP T F K
Sbjct: 354 PEGTYFVLVDFSKVKIPEDYPYPEEILNKGKDFRISHWLINELGVVAIPPTEFYIKEHEK 413
Query: 360 MGEGYVRISYATSREKLMEAMDRME 384
E +R + L A++R++
Sbjct: 414 AAENLLRFAVCKDDAYLENAVERLK 438
>pir||G81078 aminotransferase, class I NMB1473 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7226714|gb|AAF41830.1| (AE002497) aminotransferase,
class I [Neisseria meningitidis MC58]
Length = 404
Score = 145 bits (363), Expect = 7e-34
Identities = 112/389 (28%), Positives = 183/389 (46%), Gaps = 34/389 (8%)
Query: 20 KIRELFERASKMENVISLGIGEP---DFDTPKNIKEACKRALDEGWTHYTPNAGIQQLRE 76
K +L E +K ++ L IG P F+ P I R L Y + G+ R+
Sbjct: 24 KALQLEEEGNK---ILKLNIGNPAPFGFEAPDEILVDVIRNLPTS-QGYCDSKGLYSARK 79
Query: 77 AVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLA 136
A+V YY+ DI V++V I G E ++ ++LL GDE+LIP P + + A LA
Sbjct: 80 AIVHYYQTKGLRDITVDDVYIGNGVSELITMSMQALLNDGDEILIPAPDYPLWTAAATLA 139
Query: 137 EAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQD 196
EEN + P+ ++ +T KT+ IV+ PNNPTGA +E+ IA++A+
Sbjct: 140 GGTVRHYLCDEENGWFPNLADMEAKITPKTKAIVVINPNNPTGAVYSREILLEIAELARK 199
Query: 197 YNIYILSDEPYEHFIYDDAKHYPMLKFAPE-NTILANSFSKTFAMTGWRLGFVVAPSEII 255
+ + I +DE Y+ +YD A H+ + AP+ T+ N SK + + G+R G++V
Sbjct: 200 HGLIIFADEIYDKILYDGAVHHHIAALAPDLLTVTFNGLSKAYRVAGFRQGWMVLNGP-- 257
Query: 256 KEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYN-------------ERRK 302
K HA G + ++ + + A++ Y E+R
Sbjct: 258 ----KHHAK--GYIEGLDMLSSMRLCANTPMQHAIQTALGGYQSINEFILPGGRLLEQRN 311
Query: 303 LVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGM----SSEKFSEWLLEKARVVVIPGTAFG 358
+ + ++PG+ +P GA Y+FP I DT M KF LL + +V+++ GT F
Sbjct: 312 RAWELVNQIPGVSCVKPMGAMYMFPKI-DTEMYRIRDDMKFVYDLLVREKVLLVQGTGFN 370
Query: 359 KMGEGYVRISYATSREKLMEAMDRMEKAL 387
+ + RI ++ EAM R+ + L
Sbjct: 371 WIKPDHFRIVTLPYVHQIEEAMGRLARFL 399
>pir||C82564 aminotransferase XF2396 [imported] - Xylella fastidiosa (strain
9a5c) >gi|9107577|gb|AAF85195.1|AE004048_11 (AE004048)
aminotransferase [Xylella fastidiosa]
Length = 425
Score = 144 bits (360), Expect = 1e-33
Identities = 113/391 (28%), Positives = 188/391 (47%), Gaps = 24/391 (6%)
Query: 18 RSKIR-ELFERASKME----NVISLGIGEPD---FDTPKNIKEACKRALDEGWTH-YTPN 68
R +IR EL RA ++E +I L IG P F P++++ A A D G T YT
Sbjct: 20 RYEIRGELARRARELEAEGRKLIKLNIGNPGAFGFRAPEHLQRAI--ADDMGRTDPYTHQ 77
Query: 69 AGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVS 128
G+ REA+ Y + + D D + V + G E L+ +LL GDEVL+P P +
Sbjct: 78 QGLPIAREAIAAAYVRRHYPDADADRVFVGNGVSELIDLSLRALLNPGDEVLVPSPDYPL 137
Query: 129 YVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAK 188
+ L + +PV EN F PD E+ LV+ +TR IV+ PNNP+GA +E+ +
Sbjct: 138 WSAATILNDGRPVYYRCAPENGFQPDAVEIETLVSSRTRAIVLINPNNPSGANYSQELLE 197
Query: 189 AIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPEN-TILANSFSKTFAMTGWRLGF 247
I IA +++ +L DE Y+ +YD A P+ A + I + SK GWR+G+
Sbjct: 198 RIVAIAVKHHLLLLVDEIYDQILYDGAVFVPVAPLAGTHPCITFSGLSKVHRACGWRVGW 257
Query: 248 -VVAPSEIIKEMIKLHAYIIGNVASFIQVAGV----EALRSEESWKAVKEMRKEYNERRK 302
+++ S I + ++ ++G + V G A+ ++ + E R+
Sbjct: 258 ALLSGSSIQIDNLRNAMDLLGALRLCANVPGQYAIDAAVNGPDTITPLCSPGGPLYETRR 317
Query: 303 LVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEW-----LLEKARVVVIPGTAF 357
V++ + + P GA Y FPS+ G ++ F ++ L+ V+V+PG++F
Sbjct: 318 AVIEACVVSEHLSLVVPAGALYAFPSV--VGPAARHFDDYAFALELMNDEGVLVVPGSSF 375
Query: 358 GKMGEGYVRISYATSREKLMEAMDRMEKALS 388
+ R++ + E R+++ALS
Sbjct: 376 NVPYRDHFRVTLLPDAALIREVFSRIDRALS 406
>pir||E69168 probable transaminase (EC 2.6.1.-) MTH52 [similarity] -
Methanobacterium thermoautotrophicum (strain Delta H)
>gi|2621088|gb|AAB84559.1| (AE000797) aspartate
aminotransferase related protein [Methanobacterium
thermoautotrophicum]
Length = 410
Score = 143 bits (356), Expect = 4e-33
Identities = 124/414 (29%), Positives = 190/414 (44%), Gaps = 47/414 (11%)
Query: 9 IAERVILIKRSKIR-------ELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDE- 60
+ E +L+K S I E F+R + ++I +GIG+ P+ + EA RA+DE
Sbjct: 4 VNENYLLLKSSYIFSEINRRVEEFQRKNPDADIIRMGIGDVTRPLPEAVVEAFHRAVDEM 63
Query: 61 ----GWTHYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESG 116
+ Y P G LREA+ E VDI + + I+ GA T + +
Sbjct: 64 AEEETFRGYGPEQGYPFLREAIAENDYASRGVDITADEIFISDGAKCDTG-NIQEIFGLD 122
Query: 117 DEVLIPDPAFVSYVEDAKLA-EAKP----------VRIPLREENNFMPD-PDELLELVTK 164
+ V + DP + YVE +A A P V +P EEN+F+P P+E ++L
Sbjct: 123 NVVAVTDPVYPVYVESNVMAGRAGPADDDGRYSGLVYLPCTEENSFIPSLPEERVDL--- 179
Query: 165 KTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKF- 223
I + YPNNPTG TL ++ D A+D IL D YE +I +D + + +
Sbjct: 180 ----IYLCYPNNPTGTTLTEKQLAEWVDYARDSGSLILFDAAYEAYIQEDGIPHSIYEVE 235
Query: 224 -APENTILANSFSKTFAMTGWRLGFVVAPSEI-----------IKEMIKLHAYIIGNVAS 271
A E I SFSK TG R F V P E+ ++E+ N S
Sbjct: 236 GAREVAIEFRSFSKNAGFTGTRCAFTVVPEELEVPDSSGRMHSVRELWNRRQTTKFNGVS 295
Query: 272 FIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIKD 331
+ EA+ + E + ++E Y E +++ + L E G+R A Y++ +
Sbjct: 296 YPVQRAAEAVYTPEGQREIRESIDYYMENARIIRESL-ERAGLRYYGGVNAPYIWIRTPE 354
Query: 332 TGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAMDRMEK 385
GM S +F + LL A VV PG+ FG GEGY R++ S ++AM+R+ +
Sbjct: 355 -GMDSWQFFDTLLNDAEVVGTPGSGFGPSGEGYFRLTAFNSFRNTVKAMERISE 407
>pir||T21518 kynurenine--oxoglutarate transaminase (EC 2.6.1.7) /
glutamine--phenylpyruvate transaminase (EC 2.6.1.64),
cytosolic F28H6.3 [similarity] - Caenorhabditis elegans
>gi|3876523|emb|CAA20930.1| (AL031621) predicted using
Genefinder~contains similarity to Pfam domain: PF00155
(Aminotransferases class-I), Score=68.4,
E-value=4.8e-17, N=1 [Caenorhabditis elegans]
Length = 437
Score = 142 bits (355), Expect = 6e-33
Identities = 100/371 (26%), Positives = 174/371 (45%), Gaps = 44/371 (11%)
Query: 25 FERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWT----HYTPNAGIQQLREAVVE 80
F + + +SLG G PD PK + E K YT G L + +
Sbjct: 24 FGKLAIENKAVSLGQGFPDSPAPKFVTEILKDIASHPEKIESHQYTRAFGHPDLVGILSK 83
Query: 81 YYKKFYDVDIDV-ENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAK 139
Y FY V+++ ++++IT GAY Y +F + GDEV+I +PAF Y K A
Sbjct: 84 IYSYFYGVNVNATDDILITVGAYNALYYSFLGWISKGDEVIIIEPAFDCYFPQVKFAGGT 143
Query: 140 PVRIPLR------EENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADI 193
P+ + ++ + F D +EL + + K+T+MIVIN P+NPTG +E + IA++
Sbjct: 144 PISVVMKLKEGSKSASQFTIDFEELEKKINKRTKMIVINNPHNPTGKLFSREELQHIAEL 203
Query: 194 AQDYNIYILSDEPYEHFIYDDAKHYPMLKFAP-----ENTILANSFSKTFAMTGWRLGFV 248
A++Y++ +++DE YE + ++ M++FA E TI S K ++TGW+LG+
Sbjct: 204 ARNYDLIVVADEVYEFHV---SQPKEMIRFASLPGMYERTISIGSAGKALSVTGWKLGWA 260
Query: 249 VAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKE----------MRKEYN 298
+ P ++ + + + + IQ+A A ++ W E + KE
Sbjct: 261 IGPQHLLSPLKTISQNCVYTCPTPIQLAIARAF--QQDWPKFMENPNQSYLATGLPKEVM 318
Query: 299 ERRKLVLKRLKEMPGIRVKEPKGAFYV------------FPSIKDTGMSSEKFSEWLLEK 346
++RK +L + E + P+ F++ F I ++S+WL +
Sbjct: 319 QKRK-ILANMLEKANFQTILPEAGFFMLAECKLPMKSFSFSPIVGKDPLDVQYSKWLCRE 377
Query: 347 ARVVVIPGTAF 357
++ VIP + F
Sbjct: 378 KKLAVIPFSIF 388
>sp|O33267|AAT_MYCTU PROBABLE ASPARTATE AMINOTRANSFERASE (TRANSAMINASE A) (ASPAT)
>gi|7447843|pir||H70506 probable transaminase (EC
2.6.1.-) aspC [similarity] - Mycobacterium tuberculosis
(strain H37RV) >gi|2276334|emb|CAB10792.1| (Z97991) aspC
[Mycobacterium tuberculosis]
Length = 429
Score = 141 bits (353), Expect = 1e-32
Identities = 104/377 (27%), Positives = 178/377 (46%), Gaps = 22/377 (5%)
Query: 26 ERASKME----NVISLGIGEP---DFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAV 78
+ A+++E ++ L IG P F+ P I +AL Y+ + GI R AV
Sbjct: 47 QHAARLEAEGHRILKLNIGNPAPFGFEAPDVIMRDIIQALPYA-QGYSDSQGILSARRAV 105
Query: 79 VEYYKKFYDVD-IDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAE 137
V Y+ DV++V + G E + ++LL++GD+VLIP P + + LA
Sbjct: 106 VTRYELVPGFPRFDVDDVYLGNGVSELITMTLQALLDNGDQVLIPSPDYPLWTASTSLAG 165
Query: 138 AKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDY 197
PV E + PD +L +T++T+ +V+ PNNPTGA E+ + D+A+ +
Sbjct: 166 GTPVHYLCDETQGWQPDIADLESKITERTKALVVINPNNPTGAVYSCEILTQMVDLARKH 225
Query: 198 NIYILSDEPYEHFIYDDAKHYPMLKFAPENTILA-NSFSKTFAMTGWRLGF--VVAPSEI 254
+ +L+DE Y+ +YDDAKH + AP+ L N SK + + G+R G+ + P E
Sbjct: 226 QLLLLADEIYDKILYDDAKHISLASIAPDMLCLTFNGLSKAYRVAGYRAGWLAITGPKEH 285
Query: 255 IKEMIK-----LHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLK 309
I+ + + NV + Q A AL +S + + E+R + +L
Sbjct: 286 ASSFIEGIGLLANMRLCPNVPA--QHAIQVALGGHQSIEDLVLPGGRLLEQRDIAWTKLN 343
Query: 310 EMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLE---KARVVVIPGTAFGKMGEGYVR 366
E+PG+ +P GA Y FP + + + +L+ +++V GT F ++R
Sbjct: 344 EIPGVSCVKPAGALYAFPRLDPEVYDIDDDEQLVLDLLLSEKILVTQGTGFNWPAPDHLR 403
Query: 367 ISYATSREKLMEAMDRM 383
+ L A++R+
Sbjct: 404 LVTLPWSRDLAAAIERL 420
>pir||A75490 probable transaminase (EC 2.6.1.-) DR0671 [similarity] -
Deinococcus radiodurans (strain R1)
>gi|6458374|gb|AAF10249.1|AE001924_2 (AE001924)
aminotransferase, class I [Deinococcus radiodurans]
Length = 381
Score = 141 bits (353), Expect = 1e-32
Identities = 106/367 (28%), Positives = 184/367 (49%), Gaps = 31/367 (8%)
Query: 35 ISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYDVDIDVEN 94
++LG G P P + +A +RA+ YTP G+ LREA+ D+++D +
Sbjct: 26 VNLGQGFPSNPPPAFLLDAARRAVGTV-DQYTPPLGLPALREALGA------DLNVDPAD 78
Query: 95 VIITAGAYEGTY-LAFESLLESGD----EVLIPDPAFVSYVEDAKLAEAKPVRIPLR--E 147
VI+T+GA EG LA L+ + D E+++ +P + YV A+LA A+ V +PL
Sbjct: 79 VIVTSGATEGLLTLALSLLVPTRDGQPAELVVFEPVYDVYVPQAELAGARAVPVPLHLDP 138
Query: 148 ENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPY 207
E + D + +T +T+ +++N P+NPTG + +A++++++++SDE Y
Sbjct: 139 EEGWSLDLAAVRAAITPRTQALLVNTPHNPTGLVFSWAELTELVALAREHDLWLISDEVY 198
Query: 208 EHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYI-I 266
+ +Y + + + APE T S K +TGWR+G+++ P + + +
Sbjct: 199 DE-LYASERPTSLRELAPERTFTVGSAGKRLEVTGWRVGWILCPPGLGGGLSLAGGLANV 257
Query: 267 GNVASF-----IQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKG 321
V SF +Q A EAL S +R +Y RR L+ L+ + G +V EP+G
Sbjct: 258 RQVTSFCSPAPLQAAVAEALPLARSQGYYAALRADYAARRALLSSGLRSL-GAQVHEPQG 316
Query: 322 AFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAF---GKMGEGYVRISYATSREKLME 378
+++ T +E L+E V VIPG AF G +R ++ SR +L +
Sbjct: 317 TYFL------TAQHPTWTAEGLVESGAVAVIPGEAFYVTSPPPAGLLRFAFCKSRAELEQ 370
Query: 379 AMDRMEK 385
A++R+ +
Sbjct: 371 ALERLAR 377
>gb|AAF54707.1| (AE003693) CG6950 gene product [alt 3] [Drosophila melanogaster]
>gi|7299521|gb|AAF54708.1| (AE003693) CG6950 gene
product [alt 1] [Drosophila melanogaster]
>gi|7299522|gb|AAF54709.1| (AE003693) CG6950 gene
product [alt 2] [Drosophila melanogaster]
Length = 417
Score = 141 bits (353), Expect = 1e-32
Identities = 104/386 (26%), Positives = 184/386 (46%), Gaps = 36/386 (9%)
Query: 35 ISLGIGEPDFDTPKNIKEACKRALDEG---WTHYTPNAGIQQLREAVVEYYKKFYDVDID 91
++LG G PD P+ + + E YT G +L A+ + Y +++
Sbjct: 31 LNLGQGFPDDAAPEYVTHSLADIAKEQNPLLHQYTRGYGHVRLVNALSKLYSGLVGKELN 90
Query: 92 -VENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENN 150
+ +++IT+GAYE Y ++ GDEV+I +P F Y K+A P +PL+
Sbjct: 91 PLSDILITSGAYEALYSTIMGHVDVGDEVIIIEPFFDCYEPMVKMAGGVPRFVPLKLRKT 150
Query: 151 FMP--------DPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYIL 202
P D E L KT+MI++N P+NP G +++ + IA++ + +N+ +
Sbjct: 151 EGPISSADWVLDDAEFESLFNSKTKMIILNTPHNPIGKVFNRKELERIAELCRKWNVLCV 210
Query: 203 SDEPYEHFIYDDAKHYPM--LKFAPENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIK 260
SDE YE ++D A+H + L + TI S KTF++TGW++G+ P+E+I+ +
Sbjct: 211 SDEVYEWLVFDGAEHIRICTLPGMWDRTITLGSAGKTFSVTGWKIGWAYGPAELIRNLQM 270
Query: 261 LHAYIIGNVASFIQVA-----GVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIR 315
+H + + +Q VE R + + +E ++R + K L E G+R
Sbjct: 271 VHQNSVYTCPTPLQEGVARSFEVELARLGQPESYFLSLPRELKQKRDFMAKFLSE-SGMR 329
Query: 316 VKEPKGAFYVF----PSIKDTGMSSE-------KFSEWLLEKARVVVIPGTAF-----GK 359
P+G +++ P +SSE KF++W+ + + IP +AF
Sbjct: 330 PTIPEGGYFMLADWSPLAGKIDLSSEPDKHRDYKFTKWMTKNMGLQGIPPSAFYSEPNKH 389
Query: 360 MGEGYVRISYATSREKLMEAMDRMEK 385
+GE +VR + +E L +A + + K
Sbjct: 390 LGEDFVRYCFIKKQENLDKAAELLSK 415
>emb|CAC04464.1| (AL391572) conserved hypothetical protein [Neurospora crassa]
Length = 465
Score = 138 bits (345), Expect = 8e-32
Identities = 106/391 (27%), Positives = 179/391 (45%), Gaps = 39/391 (9%)
Query: 28 ASKMENVISLGIGEPDFDTPKNIKEACKRALDE-GWTHYTPNAGIQQLREAVVEYYKKFY 86
AS + ++++G G ++ P+ I A K+ALD Y+P G +LR+A+ + Y +
Sbjct: 70 ASPRQPIVNMGQGFFGYNPPEFILNAAKKALDRVECNQYSPTRGRPRLRKALSKAYAPHW 129
Query: 87 DVDIDVENVI-ITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPL 145
++D E I IT GA EG AF + +E GDEV++ +P F Y+ + ++ K V +P+
Sbjct: 130 GRELDPETEITITTGANEGMLSAFMAFIEPGDEVIVFEPFFDQYISNIEMPGGKIVYVPM 189
Query: 146 R----------EENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQ 195
+ + D DEL VT +T+M+VIN P+NP G + + IA++
Sbjct: 190 HPPKEGHIKTLSASEWTIDFDELERAVTPRTKMLVINTPHNPVGKVFSRAELERIAELCV 249
Query: 196 DYNIYILSDEPYEHFIYDDAKHYPMLKFAPEN-TILANSFSKTFAMTGWRLGFVVAPSEI 254
I ILSDE Y+ Y L E T+ S K F TGWR+G+++ P+E+
Sbjct: 250 KNQIIILSDEVYDRLFYTPFTRMATLSPEVEKITLTVGSAGKNFYATGWRVGWLMGPAEL 309
Query: 255 IKEMIKLHAYIIGNVASFIQVA---GVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEM 311
I+ + H I + S +Q A G E + W E + R + L
Sbjct: 310 IQYVAAAHTRICYSSVSPLQEACAIGFEEADQQGFWTQCIEDMQNKMSRFNAIWDEL--- 366
Query: 312 PGIRVKEPKGAFYVFPSIKDTGMSSE--------------KFSEWLLEKARVVVIPGTAF 357
G+ P+G ++V ++ + K + +L+++ V IP + F
Sbjct: 367 -GLPYSIPEGGYFVMANLNKVEIPEGYPFPPHVAERPRDFKLAWFLIQELGVAAIPPSEF 425
Query: 358 -----GKMGEGYVRISYATSREKLMEAMDRM 383
+ E ++R + E L +A +R+
Sbjct: 426 YTDVNAHIVEDWLRFAVCKPDEVLEDAKERL 456
>pir||E69093 aspartate aminotransferase related protein - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622825|gb|AAB86166.1| (AE000927) aspartate
aminotransferase related protein [Methanobacterium
thermoautotrophicum]
Length = 385
Score = 138 bits (344), Expect = 1e-31
Identities = 110/382 (28%), Positives = 187/382 (48%), Gaps = 20/382 (5%)
Query: 1 MRQKRKYFIAERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDE 60
M +KY A +V E F K + +I +G I EA ++E
Sbjct: 1 MISPKKYAKAAKVPPNGFKTSNEFFNYVFKDKEMIWMGQNTNHLHDHSEIAEAMIECINE 60
Query: 61 G-WTHYTPNAGIQQLREAVVEYYKKFYDVDI-DVENVIITAGAYEGTYLAFESLLESGDE 118
G + Y P G +L+E V++ D+ + D +ITAG E YL +LE D
Sbjct: 61 GSYCKYPPPEGFPELKELVLK------DLGLGDDFEALITAGGTESLYLCMNDILEPEDN 114
Query: 119 VLIPDPAFVSYVEDAKLAEAKPVRIPL-REENNFMPDPDELLELVTKKTRMIVINYPNNP 177
+ DP ++ A +P+ E ++ PD +LE + + TR+I + P NP
Sbjct: 115 AITCDPGYLIIDNFASRFACSVKSVPIYSSECDYKLTPDLVLENMDRDTRLISLIDPLNP 174
Query: 178 TGATLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKT 237
G++ ++ KA ADIA D+++Y+L D Y F +H+ ++APE+T+ SFSK
Sbjct: 175 LGSSYTRDEIKAFADIAVDHDVYLLHDITYRDFA---REHHLAAEYAPEHTVTVYSFSKI 231
Query: 238 FAMTGWRLGFVVAPSEIIKEMIKLHAYIIG-NVASFIQVAGVEALRSEESWKAVKEMRKE 296
M G R+G +VA S+II+ + + +G NV S Q + AL+S+ W V+ +R E
Sbjct: 232 CGMAGLRIGAIVATSDIIESVKGIVINDLGTNVVS--QAGAIAALKSKAKW--VERIRNE 287
Query: 297 YNERRKLVLKRLKEMPGIRVK-EPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGT 355
+K++ + E+ G + P + I +TG++ +++LL K ++ V G
Sbjct: 288 TLGNQKIIKAAVDEVEGAFLPVYPSNGNMMAIDIYETGVNPVDLTDYLL-KRKIFVRQGA 346
Query: 356 AFGKM-GEGYVRISYATSREKL 376
K+ G+ Y+R+S++ RE++
Sbjct: 347 YTSKIFGDRYIRLSFSIPREQV 368
>pir||B36886 probable transaminase (EC 2.6.1.-) - Streptococcus sobrinus
(strain MT3791) (fragment) >gi|633112|dbj|BAA02580.1|
(D13323) ORF1 [Streptococcus sobrinus]
Length = 302
Score = 138 bits (343), Expect = 1e-31
Identities = 84/276 (30%), Positives = 146/276 (52%), Gaps = 6/276 (2%)
Query: 111 SLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIV 170
+L+ GD +L+PDP + Y+ L PL EN+F+PD + E + ++ + I
Sbjct: 23 ALMNPGDLLLLPDPGYPDYLSGVALGRVDYETFPLLAENDFLPDLAAIPEEIARRAKFIY 82
Query: 171 INYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPM-LKFAPENTI 229
INYPNNPTG + + + A+ Y + ++SD Y + K L P ++
Sbjct: 83 INYPNNPTGRVATSDFYQDLVAWAKKYQVGVVSDFAYVPWATRAMKILAFCLHRGPRRSV 142
Query: 230 LANSFSKTFAMT--GWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESW 287
L NS +T RL F +++I+ + + ++ ++ IQ AGV AL ++
Sbjct: 143 L-NSIPSPRPLTWPAGRLAFAAGNADMIEALNLIQDHLFVSIFPAIQDAGVAALLDPQAK 201
Query: 288 KAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKA 347
+A+ ++ + Y++RR+ ++ ++ G + KG+FY + + G +S+ F++ LLEKA
Sbjct: 202 EAIVQLNQIYDQRREAFVQASAKI-GWQAFPSKGSFYAWMPV-PRGYTSQSFADLLLEKA 259
Query: 348 RVVVIPGTAFGKMGEGYVRISYATSREKLMEAMDRM 383
V V PG FG+ G+GYVRI E+L EA++R+
Sbjct: 260 HVAVAPGVGFGQAGDGYVRIGLLVEPERLAEAVERI 295
>dbj|BAB07032.1| (AP001518) aminotransferase [Bacillus halodurans]
Length = 397
Score = 137 bits (341), Expect = 2e-31
Identities = 89/366 (24%), Positives = 182/366 (49%), Gaps = 11/366 (3%)
Query: 32 ENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYDVDID 91
E+++ + + + DF P+ + +A K ++ G Y ++ + AV + K+ YD +I
Sbjct: 32 EDLLPMWVADMDFRAPQPVIDALKERVEHGVFGYPVHS--PSVDAAVKHWVKRHYDWEIR 89
Query: 92 VENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLR-EENN 150
+++ T+G E+ GDE++I P + + + E V+ PLR +
Sbjct: 90 ESDIVYTSGVVPTISYIIEAFTAVGDEIVIQTPVYYPFYQLVNNNERTLVKNPLRFDGET 149
Query: 151 FMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHF 210
+ D + L ++++KT+M+++ P+NP G KE + IA++ +++ ++SDE +
Sbjct: 150 YTMDLEHLSSVISEKTKMLILCNPHNPVGRVWRKEELEKIAELCVKHDLLLVSDEIHADL 209
Query: 211 IYDDAKHYPMLKFAPE---NTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIK--LHAYI 265
+++ KH P+ + E T + SKTF + G + + V ++ K ++ L
Sbjct: 210 VFEGKKHIPIASLSAEVASRTFTCLAPSKTFNLAGLQTSYCVIHNDKYKTRLQKYLKKRF 269
Query: 266 IGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLK-EMPGIRVKEPKGAFY 324
+G SF ++ A + W + +RK + V L+ MP + V EP+G +
Sbjct: 270 MGMSNSFAELVTEVAYNQGDEW--LLALRKYVWDNYLYVKDTLETSMPRLSVLEPEGTYL 327
Query: 325 VFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAMDRME 384
++ G+++ + +WL+++A+V + G FG G+ + R++ A R + EAM R++
Sbjct: 328 LWIDCSRLGLTASERKKWLVDEAKVAMNHGEIFGVEGQSFERMNIACPRVTVEEAMRRLK 387
Query: 385 KALSEL 390
+A L
Sbjct: 388 RAYDAL 393
>gb|AAF21128.1|L78665_2 (L78665) aspartate aminotransferase [Methylobacillus flagellatus]
Length = 429
Score = 135 bits (336), Expect = 1e-30
Identities = 103/386 (26%), Positives = 183/386 (46%), Gaps = 29/386 (7%)
Query: 24 LFERASKMEN----VISLGIGEP---DFDTPKNIKEACKRALDEGWTHYTPNAGIQQLRE 76
+ +RA +ME +I L IG P F P+ I + R +D + YT + G+ R+
Sbjct: 21 VLDRARQMEEDGHRIIKLNIGNPAPFGFAAPEEILQDVIRNMDSA-SGYTDSKGLFAARK 79
Query: 77 AVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLA 136
A++ Y ++ + ++++II G E +A ++LL +GD+VL+P P + + LA
Sbjct: 80 AIMHYTQQKNIQGVTIDDIIIGNGVSELIVMAMQALLNNGDQVLVPMPDYPLWTAAVNLA 139
Query: 137 EAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQD 196
E+ ++PD ++ +T TR IVI PNNPTGA +E + I +IA+
Sbjct: 140 GGTARHYVCDEQTGWLPDLRDIENKITANTRGIVIINPNNPTGALYPRETLEGIIEIARH 199
Query: 197 YNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILA-NSFSKTFAMTGWRLGFVVAPSEII 255
+ + I +DE Y+ ++D H + A + + N SK + G+R G++V E
Sbjct: 200 HGLVIFADEIYDKVLFDGNTHTSIASLADDVLFVTFNGLSKNYRTCGYRAGWLVISGE-- 257
Query: 256 KEMIKLHA--YIIG-NVASFIQ--------VAGVEALRSEESWKAVKEMRKEYNERRKLV 304
K HA YI G N+ + ++ V + +S + ++R L
Sbjct: 258 ----KRHAGDYIEGLNMLASMRLSRQCARAVGDPDRAGRYQSIDDLVAPTGRLCKQRDLA 313
Query: 305 LKRLKEMPGIRVKEPKGAFYVFPSIKD---TGMSSEKFSEWLLEKARVVVIPGTAFGKMG 361
K L ++PG+ +PK Y+FP + ++F LL + +V+++ GT F
Sbjct: 314 YKMLTDIPGVSCVKPKAGLYLFPRLDPKIYPIQDDQQFILDLLLEEKVLLVQGTGFNWRA 373
Query: 362 EGYVRISYATSREKLMEAMDRMEKAL 387
+ R+ + + + L EA R+ + L
Sbjct: 374 PDHFRVVFLPNVDDLTEAFTRIARFL 399
>pir||G75294 probable transaminase (EC 2.6.1.-) DR2268 [similarity] -
Deinococcus radiodurans (strain R1)
>gi|6460074|gb|AAF11814.1|AE002059_4 (AE002059)
aminotransferase, class I [Deinococcus radiodurans]
Length = 382
Score = 134 bits (334), Expect = 2e-30
Identities = 99/356 (27%), Positives = 168/356 (46%), Gaps = 14/356 (3%)
Query: 33 NVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPN-AGIQQLREAVVEYYKKFYDVDID 91
NV L IG D P ++ + + A + T+ P + Q LR+A Y + + V ++
Sbjct: 31 NVTDLSIGSSDQHPPLSVLDELRAATHDPATYRYPLFSDTQPLRDAAAAYLARRFGVRLN 90
Query: 92 VENVIITA-GAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENN 150
+ ++ GA EG ++ + GD +L+PDP + Y A +A V +PL E
Sbjct: 91 ADTEVLPLIGAQEGLAHLLLAVTDPGDTLLLPDPCYPPYWGAAAVAGLNVVTLPLLPERG 150
Query: 151 FMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHF 210
F+PD + V + R++++NYPNNPT A E + A ++ ++ D PY
Sbjct: 151 FLPDLSRVPANV--RPRVLLLNYPNNPTSAIASAEFFREAAAWCRERGTLLVHDHPYAEL 208
Query: 211 IYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVA 270
+ D + L+ E + +S SKT + G+R+GF + + + ++ I +
Sbjct: 209 TFGDYRAPSALEAGMEGVVELHSLSKTHHLGGFRVGFAAGDAGAVAALARVKGAIDFHPY 268
Query: 271 SFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVF---P 327
IQ A AL + V + + ERR +L L+++ G V+ P+ + Y + P
Sbjct: 269 LGIQRAAAHALGLPDEVGRVG--ARIFEERRDALLSALRDL-GWEVQTPQASMYAWAQVP 325
Query: 328 SIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAMDRM 383
++D S F+ E+ VVV PG AFG+ GEG+VR + E L A ++
Sbjct: 326 GLRD----SVAFAVRAAEETGVVVSPGQAFGERGEGFVRFALVQPPEVLRGAAAKL 377
>pir||T22087 hypothetical protein F42D1.2 - Caenorhabditis elegans
>gi|3876971|emb|CAB03090.1| (Z81081) predicted using
Genefinder~Similarity to Rat tyrosine aminotransferase
(SW:ATTY_RAT), contains similarity to Pfam domain:
PF00155 (Aminotransferases class-I), Score=245.7,
E-value=2e-70, N=1~cDNA EST EMBL:M88823 comes from this
gene~cDNA EST E>
Length = 464
Score = 134 bits (333), Expect = 2e-30
Identities = 100/369 (27%), Positives = 172/369 (46%), Gaps = 21/369 (5%)
Query: 32 ENVISLGIGEPDFDTPKNIKEACKRALDEG-----WTHYTPNAGIQQLREAVVEYYKKFY 86
+ VI L +G+P E +A+ E + Y P G REA+VE Y
Sbjct: 74 KKVIKLHLGDPSVGGKLPPSEIAVQAMHESVSSHMFDGYGPAVGALAAREAIVERYSSAD 133
Query: 87 DVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEA--KPVRIP 144
+V ++V++ +G +A E++ +G+ +L+P P F Y + KP +I
Sbjct: 134 NV-FTADDVVLASGCSHALQMAIEAVANAGENILVPHPGFPLYSTLCRPHNIVDKPYKID 192
Query: 145 LREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSD 204
+ E+ + D + ++ T+ I++N P NPTG KE + I A Y + I++D
Sbjct: 193 MTGEDVRI-DLSYMATIIDDNTKAIIVNNPGNPTGGVFTKEHLEEILAFAHQYKLIIIAD 251
Query: 205 EPYEHFIYDDAKHYPMLKFAPENTIL-ANSFSKTFAMTGWRLGFVV------APSEIIKE 257
E Y +Y+ A YP+ +P+ I+ + +K + + GWRLG+++ +++
Sbjct: 252 EIYGDLVYNGATFYPLASLSPKVPIITCDGIAKRWMVPGWRLGWLIIHNHFGVLTDVKNG 311
Query: 258 MIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVK 317
++ L I+G S +Q A + LR E R +V L ++PG+RV
Sbjct: 312 IVALSQKIVG-PCSLVQGALPKILR-ETPEDYFVYTRNVIETNANIVDSILADVPGMRVV 369
Query: 318 EPKGAFYVFPSIKDTGMSSE-KFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKL 376
+PKGA Y+ +I T S+ F + L+ + V +PG AF GY R+ E +
Sbjct: 370 KPKGAMYMMVNISRTAYGSDVSFCQNLIREESVFCLPGQAFS--APGYFRVVLTCGSEDM 427
Query: 377 MEAMDRMEK 385
EA R+ +
Sbjct: 428 EEAALRIRE 436
>gb|AAF27693.1|AC018848_10 (AC018848) putative aspartate aminotransferase; 38163-36256
[Arabidopsis thaliana]
Length = 394
Score = 133 bits (331), Expect = 4e-30
Identities = 99/380 (26%), Positives = 185/380 (48%), Gaps = 20/380 (5%)
Query: 19 SKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRAL-DEGWTHYTPNAGIQQLREA 77
++IR L +++ N +SL G + P+ E K + D + Y P+ G+ +LR+A
Sbjct: 20 AQIRSLM---AELTNPMSLAQGVVHWQPPQKALEKVKELVWDPIISSYGPDEGLPELRQA 76
Query: 78 VVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAE 137
+++ ++ + + V++TAGA + +L ++GD V++ +P + + ++
Sbjct: 77 LLKKLRE--ENKLTNSQVMVTAGANQAFVNLVITLCDAGDSVVMFEPYYFNSYMAFQMTG 134
Query: 138 AKPVRIPLREENNFMPDPDELLELVTKKT---RMIVINYPNNPTGATLDKEVAKAIADIA 194
+ + + + PD D L +++ +++ + P NP+G + + + K IA I
Sbjct: 135 VTNIIVGPGQSDTLYPDADWLERTLSESKPTPKVVTVVNPGNPSGTYVPEPLLKRIAQIC 194
Query: 195 QDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPSEI 254
+D +++ D YE+F+YD KH + ++ + SFSKT+ M GWRLG++ +
Sbjct: 195 KDAGCWLIVDNTYEYFMYDGLKHCCV---EGDHIVNVFSFSKTYGMMGWRLGYIAYSERL 251
Query: 255 ---IKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEM 311
E++K+ I A Q V AL W + E K + R +V + L+ +
Sbjct: 252 DGFATELVKIQDNIPICAAIISQRLAVYALEEGSGW--ITERVKSLVKNRDIVKEALEPL 309
Query: 312 PGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYAT 371
VK +GA Y++ + + K WL + VVVIPG A G GY+R+S+
Sbjct: 310 GKENVKGGEGAIYLWAKLPEGHRDDFKVVRWLAHRHGVVVIPGCASG--SPGYLRVSFGG 367
Query: 372 SRE-KLMEAMDRMEKALSEL 390
+E ++ A R+ K + EL
Sbjct: 368 LQEVEMRAAAARLRKGIEEL 387
>pir||D81146 aminotransferase, class I NMB0894 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7226131|gb|AAF41303.1| (AE002441) aminotransferase,
class I [Neisseria meningitidis MC58]
Length = 395
Score = 129 bits (320), Expect = 7e-29
Identities = 105/371 (28%), Positives = 178/371 (47%), Gaps = 30/371 (8%)
Query: 19 SKIRELFERASKMENV--ISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLRE 76
+++RE + S E + + L IGEP TPK I +A +L E Y AG+ +LR+
Sbjct: 14 ARLREAMQGISAPEGLEAVPLHIGEPKHPTPKVITDALTASLHE-LEKYPLTAGLPELRQ 72
Query: 77 AVVEYYKKFYD-VDIDVENVIITA-GAYEGTYLAFESLLESGDE-----VLIPDPAFVSY 129
A + K+ YD + +D +N I+ G+ E + +++L + ++ P+P + Y
Sbjct: 73 ACANWLKRRYDGLTVDADNEILPVLGSREALFSFVQTVLNPVSDGIKPAIVSPNPFYQIY 132
Query: 130 VEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKA 189
E A L + +F PD + E V K+T+++ + PNNP+G+ LD + K
Sbjct: 133 -EGATLLGGGEIHFANCPAPSFNPDWRSISEEVWKRTKLVFVCSPNNPSGSVLDLDGWKE 191
Query: 190 IADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAP------ENTILANSFSKTFAMTGW 243
+ D+ Y I SDE Y +D K L+ A + ++ S SK + G
Sbjct: 192 VFDLQDKYGFIIASDECYSEIYFDGNKPLGCLQAAAQLGRSRQKLLMFTSLSKRSNVPGL 251
Query: 244 RLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKL 303
R GFV +E++K + Y ++ +Q A + A E+ V + R+ Y E+ +
Sbjct: 252 RSGFVAGDAELLKNFLLYRTYHGSAMSIPVQRASIAAWDDEQH---VIDNRRMYQEKFER 308
Query: 304 VLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPG------TAF 357
V+ L+++ VK P +FY++ + D + + W +KA + V+PG T
Sbjct: 309 VIPILQQV--FDVKLPDASFYIWLKVPDGDDLALARNLW--QKAAIQVLPGRFLARDTEQ 364
Query: 358 GKMGEGYVRIS 368
G GEGYVRI+
Sbjct: 365 GNPGEGYVRIA 375
>pir||E81877 probable aminotransferase NMA1113 [imported] - Neisseria
meningitidis (group A strain Z2491)
>gi|7379807|emb|CAB84375.1| (AL162755) putative
aminotransferase [Neisseria meningitidis Z2491]
Length = 395
Score = 128 bits (318), Expect = 1e-28
Identities = 105/371 (28%), Positives = 177/371 (47%), Gaps = 30/371 (8%)
Query: 19 SKIRELFERASKMENV--ISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLRE 76
+++ E + S E + + L IGEP TPK I +A +L E Y AG+ +LR+
Sbjct: 14 ARLHEAMQGISAPEGMEAVPLHIGEPKHPTPKVITDALTASLHE-LEKYPLTAGLPELRQ 72
Query: 77 AVVEYYKKFYD-VDIDVENVIITA-GAYEGTYLAFESLLESGDE-----VLIPDPAFVSY 129
A + K+ YD + +D +N I+ G+ E + +++L + ++ P+P + Y
Sbjct: 73 ACANWLKRRYDGLTVDADNEILPVLGSREALFSFVQTVLNPVSDGIKPAIVSPNPFYQIY 132
Query: 130 VEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKA 189
E A L + +F PD + E V K+T+++ + PNNP+G+ LD + K
Sbjct: 133 -EGATLLGGGEIHFANCPAPSFNPDWRSISEEVWKRTKLVFVCSPNNPSGSVLDLDGWKE 191
Query: 190 IADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAP------ENTILANSFSKTFAMTGW 243
+ D+ Y I SDE Y +D K L+ A + ++ S SK + G
Sbjct: 192 VFDLQDKYGFIIASDECYSEIYFDGNKPLGCLQAAAQLGRSRQKLLMFTSLSKRSNVPGL 251
Query: 244 RLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKL 303
R GFV +E++K + Y ++ +Q A + A E+ V + R+ Y E+ +
Sbjct: 252 RSGFVAGDAELLKNFLLYRTYHGSAMSIPVQRASIAAWDDEQH---VIDNRRLYQEKFER 308
Query: 304 VLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPG------TAF 357
V+ L+++ VK P +FY++ + D F+ L +KA + V+PG T
Sbjct: 309 VIPILQQV--FDVKLPDASFYIWLKVPDG--DDLAFARNLWQKAAIQVLPGRFLARDTEQ 364
Query: 358 GKMGEGYVRIS 368
G GEGYVRI+
Sbjct: 365 GNPGEGYVRIA 375
>gb|AAK40460.1| Aspartate aminotransferase (aspB-1) [Sulfolobus solfataricus]
Length = 401
Score = 127 bits (317), Expect = 2e-28
Identities = 109/395 (27%), Positives = 193/395 (48%), Gaps = 27/395 (6%)
Query: 8 FIAERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALD------EG 61
F++ ++ S+IR+L + ++ +NVISL G PD T ++E K A D +
Sbjct: 5 FLSTETKYLRTSEIRDLL-KLTEGKNVISLAGGLPDPQTFP-VEEIKKIADDILLNSADK 62
Query: 62 WTHYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLI 121
YT AGI + R +V + ID NV +T G+ E ++ F LL+ GD V++
Sbjct: 63 ALQYTATAGISEFRRELVNLSRLRGISGIDERNVFVTVGSQEALFMIFNILLDPGDNVVV 122
Query: 122 PDPAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVT------KKTR-MIVINYP 174
P +++ + + + + I + E PD DEL + KK + M VI
Sbjct: 123 EAPTYLAALNAMRTRKPNFISITVTEMG---PDLDELERKIKDAHSNGKKVKLMYVIPTA 179
Query: 175 NNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTIL-ANS 233
NP G T++ E K + +IA Y+ I D+ Y +++ P+ F E ++ ++
Sbjct: 180 QNPAGTTMNTEDRKRLLEIASKYDFLIFEDDAYGFLVFEGESPPPIKAFDKEGRVIYTST 239
Query: 234 FSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEM 293
FSK A G RLG+V+A + IKEM + + S Q +EA+R + ++
Sbjct: 240 FSKILA-PGLRLGWVIAHEDFIKEMELYKQNVDLHTPSLSQYIAMEAIRRGIIQNNLPKI 298
Query: 294 RKEYNERRKLVLKRLKEM--PGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVV 351
R+ Y E+R ++L+ ++ R +P G +VF + + + K E L++ V
Sbjct: 299 RRVYKEKRDVMLEAIETYFPNDARWTKPVGGMFVFAWLPQK-IDTTKMLEKALQRG-VAY 356
Query: 352 IPGTAF--GKMGEGYVRISYA-TSREKLMEAMDRM 383
+PG++F G+ +RI+++ +E+L+E + R+
Sbjct: 357 VPGSSFYADYSGKNTMRINFSFPKKEELIEGIKRL 391
>pir||S75385 probable valine--pyruvate transaminase (EC 2.6.1.66) c04018
[similarity] - Sulfolobus solfataricus
>gi|1707790|emb|CAA69547.1| (Y08257) aminotransferase
[Sulfolobus solfataricus]
Length = 401
Score = 127 bits (317), Expect = 2e-28
Identities = 109/395 (27%), Positives = 193/395 (48%), Gaps = 27/395 (6%)
Query: 8 FIAERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALD------EG 61
F++ ++ S+IR+L + ++ +NVISL G PD T ++E K A D +
Sbjct: 5 FLSTETKYLRTSEIRDLL-KLTEGKNVISLAGGLPDPQTFP-VEEIKKIADDILLNSADK 62
Query: 62 WTHYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLI 121
YT AGI + R +V + ID NV +T G+ E ++ F LL+ GD V++
Sbjct: 63 ALQYTATAGISEFRRELVNLSRLRGISGIDERNVFVTVGSQEALFMIFNILLDPGDNVVV 122
Query: 122 PDPAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVT------KKTR-MIVINYP 174
P +++ + + + + I + E PD DEL + KK + M VI
Sbjct: 123 EAPTYLAALNAMRTRKPNFISITVTEMG---PDLDELERKIKDAHSNGKKVKLMYVIPTA 179
Query: 175 NNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTIL-ANS 233
NP G T++ E K + +IA Y+ I D+ Y +++ P+ F E ++ ++
Sbjct: 180 QNPAGTTMNTEDRKRLLEIASKYDFLIFEDDAYGFLVFEGESPPPIKAFDKEGRVIYTST 239
Query: 234 FSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEM 293
FSK A G RLG+V+A + IKEM + + S Q +EA+R + ++
Sbjct: 240 FSKILA-PGLRLGWVIAHEDFIKEMELYKQNVDLHTPSLSQYIAMEAIRRGIIQNNLPKI 298
Query: 294 RKEYNERRKLVLKRLKEM--PGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVV 351
R+ Y E+R ++L+ ++ R +P G +VF + + + K E L++ V
Sbjct: 299 RRVYKEKRDVMLEAIETYFPNDARWTKPVGGMFVFAWLPQK-IDTTKMLEKALQRG-VAY 356
Query: 352 IPGTAF--GKMGEGYVRISYA-TSREKLMEAMDRM 383
+PG++F G+ +RI+++ +E+L+E + R+
Sbjct: 357 VPGSSFYADYSGKNTMRINFSFPKKEELIEGIKRL 391
>gb|AAA42203.1| (M18340) tyrosine aminotransferase (EC 2.6.1.5) [Rattus norvegicus]
Length = 454
Score = 126 bits (314), Expect = 4e-28
Identities = 98/388 (25%), Positives = 177/388 (45%), Gaps = 28/388 (7%)
Query: 18 RSKIRELFERASKMENVISLGIGEP----DFDTPKNIKEACKRALDEG-WTHYTPNAGIQ 72
R+K + + + + VISL IG+P + T + +A K ALD G + Y P+ G
Sbjct: 57 RAKTDNMKVQPNPNKTVISLSIGDPTVFGNLPTDPEVTQAMKDALDSGKYNGYAPSIGYL 116
Query: 73 QLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVED 132
RE V YY ++ ++ ++VI+T+G + L L G +LIP P F Y
Sbjct: 117 SSREEVASYYH-CHEAPLEAKDVILTSGCSQAIELCLAVLANPGQNILIPRPGFSLY--- 172
Query: 133 AKLAEAKPVRIPLRE---ENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKA 189
LAE+ + + L E ++ D +L L+ +K +V+N P+NP G+ K +
Sbjct: 173 RTLAESMGIEVKLYNLLPEKSWEIDLKQLESLIDEKLECLVVNNPSNPCGSVFSKRHLQK 232
Query: 190 IADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILA-NSFSKTFAMTGWRLGFV 248
I +A+ + IL+DE Y ++ D K+ P+ + IL+ +K + + GWRLG++
Sbjct: 233 ILAVAERQCVPILADEIYGDMVFSDCKYEPLANLSTNVPILSCGGLAKRWLVGGWRLGWI 292
Query: 249 -------VAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERR 301
+ +EI ++KL I+G I ++++ + +
Sbjct: 293 LIHDRRDIFGNEIRDGLVKLSQRILGPCT--IVQGALKSILQRTPQEFYHDTLSFLKSNA 350
Query: 302 KLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGM----SSEKFSEWLLEKARVVVIPGTAF 357
L L ++PG++ P GA Y+ I+ + +F+E L+ + V +P T F
Sbjct: 351 DLCYGALADLPGLQPVRPSGAMYLMVGIEMEHFPEFENDVEFTERLIAEQAVHCLPATCF 410
Query: 358 GKMGEGYVRISYATSREKLMEAMDRMEK 385
+ R+ ++EA R+++
Sbjct: 411 EY--PNFFRVVITVPEVMMLEACSRIQE 436
>gi|6981630 tyrosine aminotransferase [Rattus norvegicus]
>gi|114714|sp|P04694|ATTY_RAT TYROSINE AMINOTRANSFERASE
(L-TYROSINE:2-OXOGLUTARATE AMINOTRANSFERASE) (TAT)
>gi|66641|pir||XNRTY tyrosine transaminase (EC 2.6.1.5)
- rat >gi|57328|emb|CAA26519.1| (X02741) tyrosine
aminotransferase (aa 1-454) [Rattus norvegicus]
Length = 454
Score = 126 bits (313), Expect = 5e-28
Identities = 97/374 (25%), Positives = 171/374 (44%), Gaps = 28/374 (7%)
Query: 32 ENVISLGIGEP----DFDTPKNIKEACKRALDEG-WTHYTPNAGIQQLREAVVEYYKKFY 86
+ VISL IG+P + T + +A K ALD G + Y P+ G RE V YY +
Sbjct: 71 KTVISLSIGDPTVFGNLPTDPEVTQAMKDALDSGKYNGYAPSIGYLSSREEVASYYH-CH 129
Query: 87 DVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLR 146
+ ++ ++VI+T+G + L L G +LIP P F Y LAE+ + + L
Sbjct: 130 EAPLEAKDVILTSGCSQAIELCLAVLANPGQNILIPRPGFSLY---RTLAESMGIEVKLY 186
Query: 147 E---ENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILS 203
E ++ D +L L+ +KT +V+N P+NP G+ K + I +A+ + IL+
Sbjct: 187 NLLPEKSWEIDLKQLESLIDEKTACLVVNNPSNPCGSVFSKRHLQKILAVAERQCVPILA 246
Query: 204 DEPYEHFIYDDAKHYPMLKFAPENTILA-NSFSKTFAMTGWRLGFV-------VAPSEII 255
DE Y ++ D K+ P+ + IL+ +K + + GWRLG++ + +EI
Sbjct: 247 DEIYGDMVFSDCKYEPLANLSTNVPILSCGGLAKRWLVPGWRLGWILIHDRRDIFGNEIR 306
Query: 256 KEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIR 315
++KL I+G I ++++ + + L L +PG++
Sbjct: 307 DGLVKLSQRILGPCT--IVQGALKSILQRTPQEFYHDTLSFLKSNADLCYGALAAIPGLQ 364
Query: 316 VKEPKGAFYVFPSIKDTGM----SSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYAT 371
P GA Y+ I+ + +F+E L+ + V +P T F + R+
Sbjct: 365 PVRPSGAMYLMVGIEMEHFPEFENDVEFTERLIAEQAVHCLPATCFEY--PNFFRVVITV 422
Query: 372 SREKLMEAMDRMEK 385
++EA R+++
Sbjct: 423 PEVMMLEACSRIQE 436
>sp|Q58365|HIS8_METJA PROBABLE HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMIDAZOLE
ACETOL-PHOSPHATE TRANSAMINASE) >gi|2127971|pir||C64419
histidinol-phosphate transaminase (EC 2.6.1.9) -
Methanococcus jannaschii >gi|1591622|gb|AAB98960.1|
(U67539) histidinol-phosphate aminotransferase (hisC)
[Methanococcus jannaschii]
Length = 373
Score = 126 bits (313), Expect = 5e-28
Identities = 106/365 (29%), Positives = 182/365 (49%), Gaps = 33/365 (9%)
Query: 30 KMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYDVD 89
K E++I LG E + IKE +D+ H P + + +++ KF ++
Sbjct: 36 KPEDIIKLGSNENPWGPSPKIKEKILDEIDK--IHQYP----EPVNPILMKELSKF--LN 87
Query: 90 IDVENVIITA-GAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREE 148
+D EN+I+ GA E F + ++ GDEV+IP P F Y A + AK +E
Sbjct: 88 VDEENIIVGGDGADEIIDTIFRTFVDDGDEVIIPIPTFTQYRVSATIHNAKIKYAKYDKE 147
Query: 149 NNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYE 208
+F + + +L +T KT++I + PNNPTG ++ + + + + + ++ D Y
Sbjct: 148 KDFKLNVESVLNNITDKTKVIFLCTPNNPTGNIIEN---RDVERVINETDALVVIDHAYI 204
Query: 209 HFIYDDAKHYPMLKFAPE--NTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYII 266
+ K Y + APE N I+ +FSK F + G R+G+ VA +II M+++ I
Sbjct: 205 EYA---KKEYDWTQKAPEYDNVIVLRTFSKVFGLAGMRVGYGVANKKIIDYMMRVKP--I 259
Query: 267 GNVASFIQVAGVEALRSEESW-KAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYV 325
++ QV + ALR E + + V++ K R+++ LK+ I+V P A Y+
Sbjct: 260 FSLTRLSQVCAITALRDREFFERCVRDGIKS----REMLYNGLKKFKDIKV-YPSEANYL 314
Query: 326 FPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAMDRMEK 385
+K M +++F E LL++ V+V T+F +G+ YVR+S T E ++R K
Sbjct: 315 LVELKT--MKAKEFCEELLKRG-VIVRDCTSFDGLGDNYVRVSIGT-----FEEVERFLK 366
Query: 386 ALSEL 390
L E+
Sbjct: 367 ILEEI 371
>emb|CAA09309.1| (AJ010709) tyrosine aminotransferase [Rattus norvegicus]
Length = 454
Score = 126 bits (313), Expect = 5e-28
Identities = 97/374 (25%), Positives = 171/374 (44%), Gaps = 28/374 (7%)
Query: 32 ENVISLGIGEP----DFDTPKNIKEACKRALDEG-WTHYTPNAGIQQLREAVVEYYKKFY 86
+ VISL IG+P + T + +A K ALD G + Y P+ G RE V YY +
Sbjct: 71 KTVISLSIGDPTVFGNLPTDPEVTQAMKDALDSGKYNGYAPSIGYLSSREEVASYYH-CH 129
Query: 87 DVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLR 146
+ ++ ++VI+T+G + L L G +LIP P F Y LAE+ + + L
Sbjct: 130 EAPLEAKDVILTSGCSQAIELCLAVLANPGQNILIPRPGFSLY---RTLAESMGIEVKLY 186
Query: 147 E---ENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILS 203
E ++ D +L L+ +KT +V+N P+NP G+ K + I +A+ + IL+
Sbjct: 187 NLLPEKSWEIDLKQLESLIDEKTACLVVNNPSNPCGSVFSKRHLQKILAVAERQCVPILA 246
Query: 204 DEPYEHFIYDDAKHYPMLKFAPENTILA-NSFSKTFAMTGWRLGFV-------VAPSEII 255
DE Y ++ D K+ P+ + IL+ +K + + GWRLG++ + +EI
Sbjct: 247 DEIYGDMVFSDCKYEPLANLSTNVPILSCGGLAKRWLVLGWRLGWILIHDRRDIFGNEIR 306
Query: 256 KEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIR 315
++KL I+G I ++++ + + L L +PG++
Sbjct: 307 DGLVKLSQRILGPCT--IVQGALKSILQRTPQEFYHDTLSFLKSNADLCYGALAAIPGLQ 364
Query: 316 VKEPKGAFYVFPSIKDTGM----SSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYAT 371
P GA Y+ I+ + +F+E L+ + V +P T F + R+
Sbjct: 365 PVRPSGAMYLMVGIEMEHFPEFENDVEFTERLIAEQAVHCLPATCFEY--PNFFRVVITV 422
Query: 372 SREKLMEAMDRMEK 385
++EA R+++
Sbjct: 423 PEVMMLEACSRIQE 436
>pir||S76639 probable transaminase (EC 2.6.1.-) sll0480 [similarity] -
Synechocystis sp. (strain PCC 6803)
>gi|1001746|dbj|BAA10583.1| (D64004) hypothetical
protein [Synechocystis sp.]
Length = 412
Score = 125 bits (310), Expect = 1e-27
Identities = 113/392 (28%), Positives = 174/392 (43%), Gaps = 38/392 (9%)
Query: 25 FERASKMENVISLGIGEPDFDTPKNIKEACKRALDE-----GWTHYTPNAGIQQLREAVV 79
F A+ VI LGIG+ P ++A +A+D+ + Y P G LRE +
Sbjct: 27 FTTANPNAQVIKLGIGDVTEPLPLACRQAMAKAIDDMGDRQTFKGYGPEQGYAWLREKIA 86
Query: 80 EYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLA--- 136
++ + +++ E + I+ G+ T + + + + + DP + YV+ +A
Sbjct: 87 QHDFQARGCEVNAEEIFISDGSKCDTGNILD-IFGKDNTIAVTDPVYPVYVDTNVMAGHT 145
Query: 137 -EAKP-------VRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAK 188
+A V +P+ EN+F+ + +KK +I + +PNNPTGAT K K
Sbjct: 146 GDANEKGEYGGLVYLPISAENDFVA------AIPSKKVDLIYLCFPNNPTGATATKAYLK 199
Query: 189 AIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKF--APENTILANSFSKTFAMTGWRLG 246
D A + I D YE FI D + + + A + I SFSK TG R
Sbjct: 200 QWVDYALAHGSIIFFDAAYEAFITDPTLPHSIYEIEGARDCAIEFRSFSKNAGFTGTRCA 259
Query: 247 FVVAPSEIIK--------EMIKL---HAYIIGNVASFIQVAGVEALRSEESWKAVKEMRK 295
V P + E+ KL N S+I G EA+ S E V+E+
Sbjct: 260 LTVVPKTLTAKAADGSDVELWKLWNRRQSTKFNGVSYIIQRGAEAVYSPEGQAQVQELIA 319
Query: 296 EYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGT 355
Y E +++ ++L G++V A YV+ G+SS F + LL VV PG+
Sbjct: 320 FYLENARIIREKLAAA-GLQVYGGINAPYVWVKTPH-GLSSWDFFDKLLHTVNVVGTPGS 377
Query: 356 AFGKMGEGYVRISYATSREKLMEAMDRMEKAL 387
FG GEGY RIS SR + EAM+R+ L
Sbjct: 378 GFGAAGEGYFRISAFNSRANVEEAMERITSTL 409
>gb|AAG37063.1|AF301900_1 (AF301900) ROOTY/SUPERROOT1 [Arabidopsis thaliana]
Length = 462
Score = 125 bits (310), Expect = 1e-27
Identities = 105/388 (27%), Positives = 183/388 (47%), Gaps = 25/388 (6%)
Query: 18 RSKIRELFERASKMEN--VISLGIGEPD----FDTPKNIKEACKRALDEG-WTHYTPNAG 70
R I LF+ K N ++ LG G+P F T ++A L G Y P AG
Sbjct: 50 RGVIYMLFDNCGKDVNKTILPLGHGDPSVYPCFRTCIEAEDAVVDVLRSGKGNSYGPGAG 109
Query: 71 IQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYV 130
I R AV +Y + + E++ +TAG +G + FESL +L+P P F Y
Sbjct: 110 ILPARRAVADYMNRDLPHKLTPEDIFLTAGCNQGIEIVFESLARPNANILLPRPGFPHYD 169
Query: 131 EDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAI 190
A + + + L E + D + + + +KT +V+ PNNP G + K +
Sbjct: 170 ARAAYSGLEVRKFDLLPEKEWEIDLEGIEAIADEKTVAMVVINPNNPCGNVYSHDHLKKV 229
Query: 191 ADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILA-NSFSKTFAMTGWRLGFV- 248
A+ A+ I ++SDE Y+ I+ D PM KFA +L SK + + GW++G++
Sbjct: 230 AETARKLGIMVISDEVYDRTIFGDNPFVPMGKFASIVPVLTLAGISKGWVVPGWKIGWIA 289
Query: 249 ------VAPSEIIKEMIKLHAYIIGNVASFIQVAGVEAL-RSEESWKAVKEMRKEYNERR 301
V + + + IK + + + A+ IQ A L ++++++ A K ++N
Sbjct: 290 LNDPEGVFETTKVLQSIKQNLDVTPDPATIIQAALPAILEKADKNFFAKKNKILKHNV-- 347
Query: 302 KLVLKRLKEMPGIRV-KEPKGAFYVFPSIKDTGMSSEK----FSEWLLEKARVVVIPGTA 356
LV RLK++P + K+P+ Y+ ++ + M + K F L + +V +PG A
Sbjct: 348 DLVCDRLKDIPCVVCPKKPESCTYLLTKLELSLMDNIKDDIDFCVKLAREENLVFLPGDA 407
Query: 357 FGKMGEGYVRISYATSREKLMEAMDRME 384
G + ++RI+ L +A++R++
Sbjct: 408 LGL--KNWMRITIGVEAHMLEDALERLK 433
>gb|AAG37062.1|AF301899_1 (AF301899) ROOTY/SUPERROOT1 [Arabidopsis thaliana]
Length = 462
Score = 124 bits (309), Expect = 1e-27
Identities = 105/388 (27%), Positives = 183/388 (47%), Gaps = 25/388 (6%)
Query: 18 RSKIRELFERASKMEN--VISLGIGEPD----FDTPKNIKEACKRALDEG-WTHYTPNAG 70
R I LF+ K N ++ LG G+P F T ++A L G Y P AG
Sbjct: 50 RGVIYMLFDNCGKDVNKTILPLGHGDPSVYPCFRTCIEAEDAVVDVLRSGKGNSYGPGAG 109
Query: 71 IQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYV 130
I R AV +Y + + E++ +TAG +G + FESL +L+P P F Y
Sbjct: 110 ILPARRAVADYMNRDLPHKLTPEDIFLTAGCNQGIEIVFESLARPNANILLPRPGFPHYD 169
Query: 131 EDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAI 190
A + + + L E + D + + + +KT +V+ PNNP G + K +
Sbjct: 170 ARAAYSGLEVRKFDLLPEKEWEIDLEGIEAIADEKTVAMVVINPNNPCGNVYSHDHLKKV 229
Query: 191 ADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILA-NSFSKTFAMTGWRLGFV- 248
A+ A+ I ++SDE Y+ I+ D PM KFA +L SK + + GW++G++
Sbjct: 230 AETARKLGIMVISDEVYDRTIFGDNPFVPMGKFASIVPVLTLAGISKGWVVPGWKIGWIA 289
Query: 249 ------VAPSEIIKEMIKLHAYIIGNVASFIQVAGVEAL-RSEESWKAVKEMRKEYNERR 301
V + + + IK + + + A+ IQ A L ++++++ A K ++N
Sbjct: 290 LNDPEGVFETTKVLQSIKQNLDVTPDPATIIQAALPAILEKADKNFFAKKNKILKHNV-- 347
Query: 302 KLVLKRLKEMPGIRV-KEPKGAFYVFPSIKDTGMSSEK----FSEWLLEKARVVVIPGTA 356
LV RLK++P + K+P+ Y+ ++ + M + K F L + +V +PG A
Sbjct: 348 DLVCDRLKDIPCVVCPKKPESCTYLLTKLELSLMDNIKDDIDFCVKLAREENLVFLPGYA 407
Query: 357 FGKMGEGYVRISYATSREKLMEAMDRME 384
G + ++RI+ L +A++R++
Sbjct: 408 LGL--KNWMRITIGVEAHMLEDALERLK 433
>pir||C71917 probable transaminase (EC 2.6.1.-) jhp0568 [similarity] -
Helicobacter pylori (strain J99)
>gi|4155107|gb|AAD06139.1| (AE001489) AMINOTRANSFERASE
[Helicobacter pylori J99]
Length = 375
Score = 123 bits (306), Expect = 3e-27
Identities = 105/379 (27%), Positives = 184/379 (47%), Gaps = 37/379 (9%)
Query: 20 KIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVV 79
++R LF+ + + + LGIGEP F+TPK I++A K + Y +A + LREA
Sbjct: 10 RLRALFKEITPKKKGLDLGIGEPRFETPKFIQDALK-SHTHSLNIYPKSAFEESLREAQR 68
Query: 80 EYYKKFYDVDIDVENVIITAGAYE--GTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAE 137
++K+ + +++ ++ T G+ E + +F + P+P + Y A+ A
Sbjct: 69 GFFKRRFKIELKENELVSTLGSREVLFNFPSFVLFDYPNPTIAYPNPFYQIYEGSAQFAR 128
Query: 138 AKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDY 197
AK + +PL +EN+F P L E ++ ++++N PNNPTG TL E A +A +
Sbjct: 129 AKSLLMPLVKENDFTP---SLNEKELQEVDLVILNSPNNPTGRTLSLEELIAWVKLALKH 185
Query: 198 NIYILSDEPYEHFIYDDAKHYPMLKF-------APENTILANSFSKTFAMTGWRLGFVVA 250
+ +++DE Y IY++ +L+ A +N ++ +S SK + G R GF+
Sbjct: 186 DFILINDECYSE-IYENTPPSSLLEACMLADNGAFKNVLVIHSLSKRSSAPGLRSGFIAG 244
Query: 251 PSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESW---KAVKEMRKEYNERRKLVLKR 307
S ++++ Y+ A+ IQ A SE +W + + R Y KL K
Sbjct: 245 DSSLLEKYKAFRTYLGYTSANAIQKA------SEVAWLDDRHAEFFRNIYANNLKLARKI 298
Query: 308 LKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGK--MGEGYV 365
KE + P +FY + +KD E F++ L + + +P G+ +G YV
Sbjct: 299 FKE----TLIYPY-SFYAYLPVKD----GENFAKTLYQNEGITTLPALYLGRNHIGADYV 349
Query: 366 RIS--YATS-REKLMEAMD 381
R++ Y TS EK +E ++
Sbjct: 350 RLALVYDTSLLEKPLEIIE 368
>gi|4507369 tyrosine aminotransferase; Tyrosine aminotransferase, cytosolic
[Homo sapiens] >gi|114713|sp|P17735|ATTY_HUMAN TYROSINE
AMINOTRANSFERASE (L-TYROSINE:2-OXOGLUTARATE
AMINOTRANSFERASE) (TAT) >gi|88955|pir||S10887 tyrosine
transaminase (EC 2.6.1.5) - human
>gi|2136247|pir||S60718 tat protein - human
>gi|36713|emb|CAA36750.1| (X52520) tyrosine
aminotransferase (AA 1-454) [Homo sapiens]
>gi|37502|emb|CAA39210.1| (X55675) tyrosine
aminotransferase [Homo sapiens]
>gi|1217965|emb|CAA36749.1| (X52509) tyrosine
aminotransferase [Homo sapiens]
>gi|1093948|prf||2105189A Tyr aminotransferase [Homo
sapiens]
Length = 454
Score = 122 bits (302), Expect = 9e-27
Identities = 94/374 (25%), Positives = 170/374 (45%), Gaps = 28/374 (7%)
Query: 32 ENVISLGIGEP----DFDTPKNIKEACKRALDEG-WTHYTPNAGIQQLREAVVEYYKKFY 86
+ +ISL IG+P + T + +A K ALD G + Y P+ G RE + YY
Sbjct: 71 KTMISLSIGDPTVFGNLPTDPEVTQAMKDALDSGKYNGYAPSIGFLSSREEIASYYH-CP 129
Query: 87 DVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLR 146
+ ++ ++VI+T+G + L L G +L+P P F Y LAE+ + + L
Sbjct: 130 EAPLEAKDVILTSGCSQAIDLCLAVLANPGQNILVPRPGFSLY---KTLAESMGIEVKLY 186
Query: 147 E---ENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILS 203
E ++ D +L L+ +KT +++N P+NP G+ K + I +A + IL+
Sbjct: 187 NLLPEKSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILA 246
Query: 204 DEPYEHFIYDDAKHYPMLKFAPENTILA-NSFSKTFAMTGWRLGFV-------VAPSEII 255
DE Y ++ D K+ P+ + + IL+ +K + + GWRLG++ + +EI
Sbjct: 247 DEIYGDMVFSDCKYEPLATLSTDVPILSCGGLAKRWLVPGWRLGWILIHDRRDIFGNEIR 306
Query: 256 KEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIR 315
++KL I+G I ++++ + L L +PG+R
Sbjct: 307 DGLVKLSQRILGPCT--IVQGALKSILCRTPGEFYHNTLSFLKSNADLCYGALAAIPGLR 364
Query: 316 VKEPKGAFYVFPSIKDTGM----SSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYAT 371
P GA Y+ I+ + +F+E L+ + V +P T F ++R+
Sbjct: 365 PVRPSGAMYLMVGIEMEHFPEFENDVEFTERLVAEQSVHCLPATCFEY--PNFIRVVITV 422
Query: 372 SREKLMEAMDRMEK 385
++EA R+++
Sbjct: 423 PEVMMLEACSRIQE 436
>gi|11432387 tyrosine aminotransferase [Homo sapiens]
Length = 486
Score = 122 bits (302), Expect = 9e-27
Identities = 94/374 (25%), Positives = 170/374 (45%), Gaps = 28/374 (7%)
Query: 32 ENVISLGIGEP----DFDTPKNIKEACKRALDEG-WTHYTPNAGIQQLREAVVEYYKKFY 86
+ +ISL IG+P + T + +A K ALD G + Y P+ G RE + YY
Sbjct: 103 KTMISLSIGDPTVFGNLPTDPEVTQAMKDALDSGKYNGYAPSIGFLSSREEIASYYH-CP 161
Query: 87 DVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLR 146
+ ++ ++VI+T+G + L L G +L+P P F Y LAE+ + + L
Sbjct: 162 EAPLEAKDVILTSGCSQAIDLCLAVLANPGQNILVPRPGFSLY---KTLAESMGIEVKLY 218
Query: 147 E---ENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILS 203
E ++ D +L L+ +KT +++N P+NP G+ K + I +A + IL+
Sbjct: 219 NLLPEKSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILA 278
Query: 204 DEPYEHFIYDDAKHYPMLKFAPENTILA-NSFSKTFAMTGWRLGFV-------VAPSEII 255
DE Y ++ D K+ P+ + + IL+ +K + + GWRLG++ + +EI
Sbjct: 279 DEIYGDMVFSDCKYEPLATLSTDVPILSCGGLAKRWLVPGWRLGWILIHDRRDIFGNEIR 338
Query: 256 KEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIR 315
++KL I+G I ++++ + L L +PG+R
Sbjct: 339 DGLVKLSQRILGPCT--IVQGALKSILCRTPGEFYHNTLSFLKSNADLCYGALAAIPGLR 396
Query: 316 VKEPKGAFYVFPSIKDTGM----SSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYAT 371
P GA Y+ I+ + +F+E L+ + V +P T F ++R+
Sbjct: 397 PVRPSGAMYLMVGIEMEHFPEFENDVEFTERLVAEQSVHCLPATCFEY--PNFIRVVITV 454
Query: 372 SREKLMEAMDRMEK 385
++EA R+++
Sbjct: 455 PEVMMLEACSRIQE 468
>gb|AAD21706.1| (AC007048) putative tyrosine aminotransferase [Arabidopsis
thaliana] >gi|11527939|gb|AAG37061.1|AF301898_1
(AF301898) ROOTY/SUPERROOT1 [Arabidopsis thaliana]
Length = 462
Score = 120 bits (297), Expect = 4e-26
Identities = 103/388 (26%), Positives = 181/388 (46%), Gaps = 25/388 (6%)
Query: 18 RSKIRELFERASKMEN--VISLGIGEPD----FDTPKNIKEACKRALDEG-WTHYTPNAG 70
R I LF+ K N ++ LG G+P F T ++A L G Y P AG
Sbjct: 50 RGVIYMLFDNCGKDVNKTILPLGHGDPSVYPCFRTCIEAEDAVVDVLRSGKGNSYGPGAG 109
Query: 71 IQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYV 130
I R AV +Y + + E++ +TAG +G + FESL +L+P P F Y
Sbjct: 110 ILPARRAVADYMNRDLPHKLTPEDIFLTAGCNQGIEIVFESLARPNANILLPRPGFPHYD 169
Query: 131 EDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAI 190
A + + + L E + D + + + + T +V+ PNNP G + K +
Sbjct: 170 ARAAYSGLEVRKFDLLPEKEWEIDLEGIEAIADENTVAMVVINPNNPCGNVYSHDHLKKV 229
Query: 191 ADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILA-NSFSKTFAMTGWRLGFV- 248
A+ A+ I ++SDE Y+ I+ D M KFA +L SK + + GW++G++
Sbjct: 230 AETARKLGIMVISDEVYDRTIFGDNPFVSMGKFASIVPVLTLAGISKGWVVPGWKIGWIA 289
Query: 249 ------VAPSEIIKEMIKLHAYIIGNVASFIQVAGVEAL-RSEESWKAVKEMRKEYNERR 301
V + + + IK + + + A+ IQ A L ++++++ A K ++N
Sbjct: 290 LNDPEGVFETTKVLQSIKQNLDVTPDPATIIQAALPAILEKADKNFFAKKNKILKHNV-- 347
Query: 302 KLVLKRLKEMPGIRV-KEPKGAFYVFPSIKDTGMSSEK----FSEWLLEKARVVVIPGTA 356
LV RLK++P + K+P+ Y+ ++ + M + K F L + +V +PG A
Sbjct: 348 DLVCDRLKDIPCVVCPKKPESCTYLLTKLELSLMDNIKDDIDFCVKLAREENLVFLPGDA 407
Query: 357 FGKMGEGYVRISYATSREKLMEAMDRME 384
G + ++RI+ L +A++R++
Sbjct: 408 LGL--KNWMRITIGVEAHMLEDALERLK 433
>pir||E71243 probable valine--pyruvate transaminase (EC 2.6.1.66) PH0207
[similarity] - Pyrococcus horikoshii
>gi|3256593|dbj|BAA29276.1| (AP000001) 428aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 428
Score = 119 bits (296), Expect = 5e-26
Identities = 102/400 (25%), Positives = 203/400 (50%), Gaps = 26/400 (6%)
Query: 8 FIAERVILIKRSKIRELFERASKMENVISLGIGEPDFDT-PKNI-----KEACKRALDEG 61
F +++ + ++ S++REL + + ++ISL G P+ T PK I E ++ D+
Sbjct: 33 FFSKKALEMRASEVRELLKLV-ETSDIISLAGGLPNPKTFPKEIIRDILVEIMEKYADKA 91
Query: 62 WTHYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLI 121
Y G LRE ++++ K Y + D +++IT+G+ + L L GD V++
Sbjct: 92 -LQYGTTKGFTPLRETLMKWLGKRYGISQD-NDIMITSGSQQALDLIGRVFLNPGDIVVV 149
Query: 122 PDPAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYP----NNP 177
P +++ ++ E + ++IPL +E + +E L+ + + + + + Y NP
Sbjct: 150 EAPTYLAALQAFNFYEPQYIQIPLDDEGMKVEILEEKLKELKSQGKKVKVVYTVPTFQNP 209
Query: 178 TGATLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTIL-ANSFSK 236
G T++++ K + ++A +Y+ ++ D+PY Y + E ++ +FSK
Sbjct: 210 AGVTMNEDRRKYLLELASEYDFIVVEDDPYGELRYSGNPEKKIKALDNEGRVIYLGTFSK 269
Query: 237 TFAMTGWRLGFVVAPSEIIK--EMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMR 294
A G+R+G++V II+ E+ K + NV F QV + K + E+R
Sbjct: 270 ILA-PGFRIGWMVGDPGIIRKMEIAKQSTDLCTNV--FGQVVAWRYVDGGYLEKHIPEIR 326
Query: 295 KEYNERRKLVLKRLKE-MP-GIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVI 352
K Y RR +L+ L+E MP G++ +P+G +++ ++ D G+ S+K E ++K V +
Sbjct: 327 KFYKPRRDAMLEALEEFMPEGVKWTKPEGGMFIWVTLPD-GIDSKKMLERAIKKG-VAYV 384
Query: 353 PGTAF--GKMGEGYVRISYA-TSREKLMEAMDRMEKALSE 389
PG AF + + +R+++ +K+ME + R+ + + E
Sbjct: 385 PGEAFYAHRDVKNTMRLNFTYVDEDKIMEGIKRLAETIKE 424
>pir||H64597 probable transaminase (EC 2.6.1.-) HP0624 [similarity] -
Helicobacter pylori (strain 26695)
>gi|2313744|gb|AAD07687.1| (AE000576) solute-binding
signature and mitochondrial signature protein (aspB)
[Helicobacter pylori 26695]
Length = 375
Score = 117 bits (291), Expect = 2e-25
Identities = 98/379 (25%), Positives = 180/379 (46%), Gaps = 34/379 (8%)
Query: 20 KIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVV 79
++R L + + + + LGIGEP F+TPK I++A K Y +A + LR A
Sbjct: 10 RLRALLKEITPKKRGLDLGIGEPQFETPKFIQDALKNH-THSLNIYPKSAFEESLRAAQR 68
Query: 80 EYYKKFYDVDIDVENVIITAGAYE--GTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAE 137
++K+ + +++ +I T G+ E + +F + P+P + Y AK +
Sbjct: 69 GFFKRRFKIELKENELISTLGSREVLFNFPSFVLFDYQNPTIAYPNPFYQIYEGAAKFIK 128
Query: 138 AKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDY 197
AK + +PL +EN+F P L E ++ ++++N PNNPTG TL E + +A +
Sbjct: 129 AKSLLMPLTKENDFTP---SLNEKELQEVDLVILNSPNNPTGRTLSLEELISWVKLALKH 185
Query: 198 NIYILSDEPYEHFIYDDAKHYPMLKF-------APENTILANSFSKTFAMTGWRLGFVVA 250
+ +++DE Y IY++ +L+ A +N ++ +S SK + G R GF+
Sbjct: 186 DFILINDECYSE-IYENTPPPSLLEACMLAGNEAFKNVLVIHSLSKRSSAPGLRSGFIAG 244
Query: 251 PSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESW---KAVKEMRKEYNERRKLVLKR 307
S ++++ AY+ A+ IQ A SE +W + + R Y KL K
Sbjct: 245 DSRLLEKYKAFRAYLGYTSANAIQKA------SEAAWLDDRHAEFFRNIYANNLKLARKI 298
Query: 308 LKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFG--KMGEGYV 365
K + P +FYV+ ++ + E F++ L + ++ +P G ++G YV
Sbjct: 299 FKN----TLIYPY-SFYVYLPVQ----NGENFAKTLYQNEGIITLPALYLGRNRIGADYV 349
Query: 366 RISYATSREKLMEAMDRME 384
R++ L + ++ +E
Sbjct: 350 RLALVYDTPLLEKPLEIIE 368
>pir||F83189 probable aminotransferase PA3659 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9949820|gb|AAG07047.1|AE004785_11 (AE004785)
probable aminotransferase [Pseudomonas aeruginosa]
Length = 402
Score = 117 bits (291), Expect = 2e-25
Identities = 101/377 (26%), Positives = 164/377 (42%), Gaps = 33/377 (8%)
Query: 35 ISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYDVD---ID 91
I+L IGEP +P + E LD+ Y G+ LREA+ + ++ + V +D
Sbjct: 32 IALSIGEPKHRSPSFVAETLAENLDQ-LAVYPTTLGLPALREAIARWCERRFSVPAGWLD 90
Query: 92 VENVIITAGAYEGTYLAFESLLESGDE-------VLIPDPAFVSYVEDAKLAEAKPVRIP 144
++ AF + E V+ P+P + Y A LA A P +P
Sbjct: 91 AARHVLPVNGTREALFAFTQTVVRRSEPGEAPGLVVSPNPFYQIYEGAALLAGAVPHYLP 150
Query: 145 LREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSD 204
REEN F PD D + E ++ +++ + P NPTGA + E K + +A Y+ I +D
Sbjct: 151 CREENGFNPDFDAVDEATWQRCQILFLCSPGNPTGALVPLETLKKLIALADRYDFVIAAD 210
Query: 205 EPYEHFIYDDAKHYPMLKFAP--------ENTILANSFSKTFAMTGWRLGFVVAPSEIIK 256
E Y +D+ P L A ++ +S SK + G R GFV +EI+K
Sbjct: 211 ECYSELYFDENAPPPGLLNACAELGRTDFSRCVVFHSLSKRSNLPGLRSGFVAGDAEILK 270
Query: 257 EMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRV 316
+ + Y + Q+A + A E V+ R Y E+ VL L + + V
Sbjct: 271 KFLLYRTYHGCAMPVQTQLASIAAWNDEVH---VRANRSLYREKFDAVLAILDGV--LDV 325
Query: 317 KEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGK------MGEGYVRISYA 370
+ P G+FY++ T + F+ L E+ V V+PG+ + G VR++
Sbjct: 326 QRPDGSFYLWAR---TPVDDTVFTRELFEQQHVTVVPGSYLSREVDGENPGANRVRMALV 382
Query: 371 TSREKLMEAMDRMEKAL 387
+ +EA +R+ L
Sbjct: 383 APLAECVEAAERIRDYL 399
>gb|AAD15433.1| (AC006218) putative aspartate aminotransferase [Arabidopsis
thaliana]
Length = 429
Score = 117 bits (290), Expect = 2e-25
Identities = 109/390 (27%), Positives = 176/390 (44%), Gaps = 39/390 (10%)
Query: 22 RELFERASKMENV--ISLGIGEPDFDTPKNIKEACKR-----ALDEGWTHYTPNAGIQQL 74
REL E K NV ISLG G+ P+ I + EG+ Y G + L
Sbjct: 32 REL-EHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTL 90
Query: 75 REAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAK 134
R+A+ E + + D+ + V ++ GA + + LL S + + DP F +Y++ +
Sbjct: 91 RKAIAETF--YRDLHVKSNEVFVSDGA-QSDISRLQLLLGSNVTIAVQDPTFPAYIDSSV 147
Query: 135 LAEA------------KPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATL 182
+ V +P N+F PD +T +T +I PNNPTG
Sbjct: 148 IIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDL-----AMTPRTDVIFFCSPNNPTGYVA 202
Query: 183 DKEVAKAIADIAQDYNIYILSDEPYEHFIYDDA-KHYPMLKFAPENTILANSFSKTFAMT 241
++ + D A+ I+ D Y FI D + + + A E I +SFSK T
Sbjct: 203 SRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFT 262
Query: 242 GWRLGFVVAPSEIIKE-----MIKLHAYIIG--NVASFIQVAGVEALRSEESWKAVKEMR 294
G RLG+ + P E++ + H + N AS I AG A S K ++ +
Sbjct: 263 GVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVN 322
Query: 295 KEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPG 354
Y E RK+++ L + G++V A Y++ K + S + F+E +LE ++ +PG
Sbjct: 323 NYYKENRKILMDTLVSL-GLKVYGGVNAPYLWVHFKGS-KSWDVFNE-ILENTHIITVPG 379
Query: 355 TAFGKMGEGYVRISYATSREKLMEAMDRME 384
+ FG GE Y+RIS R+ ++EA R++
Sbjct: 380 SGFGPGGEEYLRISGFGRRDHIVEASKRLQ 409
>gb|AAC67987.2| (AE001312) Aspartate Aminotransferase [Chlamydia trachomatis]
Length = 394
Score = 117 bits (290), Expect = 2e-25
Identities = 99/378 (26%), Positives = 165/378 (43%), Gaps = 30/378 (7%)
Query: 25 FERASKMENVISLGIGEPDFDTPKNIKEACKRALDE-----GWTHYTPNAGIQQLREAVV 79
F + VI+L IG+ ++ EA ++ Y P+ G+ LR+ +
Sbjct: 26 FRLENPQHTVINLSIGDTTQPLNASVAEAFASSIARLSSPTTCRGYGPDFGLPALRQKLS 85
Query: 80 EYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAK 139
E FY +D + + I+ GA + S V I DP++ +Y++ A+L AK
Sbjct: 86 E---DFYRGFVDAKEIFISDGAKVDLFRLL-SFFGPNQTVAIQDPSYPAYLDIARLTGAK 141
Query: 140 PV-RIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYN 198
+ +P +EN F P+ E + ++ + PNNPTG L+K+ +AI A ++
Sbjct: 142 EIIALPCLQENAFFPEFPEDTHI-----DILCLCSPNNPTGTVLNKDQLRAIVHYAIEHE 196
Query: 199 IYILSDEPYEHFIYDDAKHYPMLKFAPEN--TILANSFSKTFAMTGWRLGFVVAPSE--- 253
I IL D Y FI D + + + I NSFSK G RLG+ V P E
Sbjct: 197 ILILFDAAYSTFISDPSLPKSIFEIPDARFCAIEINSFSKPLGFAGIRLGWTVIPQELTY 256
Query: 254 -----IIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRL 308
+I++ + + + Q AGV L +A+ R+ + RK +L
Sbjct: 257 ADGHFVIQDWERFLSTTFNGASIPAQEAGVAGLSILPQLEAIHYYRENSDLLRKALLAT- 315
Query: 309 KEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRIS 368
G V + A Y++ +S ++ L + + + PG FG+ G G+VR S
Sbjct: 316 ----GFEVFGGEHAPYLWVKPTQANISDRDLFDFFLREYHIAITPGIGFGRSGSGFVRFS 371
Query: 369 YATSREKLMEAMDRMEKA 386
RE ++ A +R++ A
Sbjct: 372 SLGKREDILAACERLQMA 389
>pir||D71520 probable transaminase (EC 2.6.1.-) aspC [similarity] - Chlamydia
trachomatis (serotype D, strain UW3/Cx)
Length = 400
Score = 117 bits (290), Expect = 2e-25
Identities = 99/378 (26%), Positives = 165/378 (43%), Gaps = 30/378 (7%)
Query: 25 FERASKMENVISLGIGEPDFDTPKNIKEACKRALDE-----GWTHYTPNAGIQQLREAVV 79
F + VI+L IG+ ++ EA ++ Y P+ G+ LR+ +
Sbjct: 32 FRLENPQHTVINLSIGDTTQPLNASVAEAFASSIARLSSPTTCRGYGPDFGLPALRQKLS 91
Query: 80 EYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAK 139
E FY +D + + I+ GA + S V I DP++ +Y++ A+L AK
Sbjct: 92 E---DFYRGFVDAKEIFISDGAKVDLFRLL-SFFGPNQTVAIQDPSYPAYLDIARLTGAK 147
Query: 140 PV-RIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYN 198
+ +P +EN F P+ E + ++ + PNNPTG L+K+ +AI A ++
Sbjct: 148 EIIALPCLQENAFFPEFPEDTHI-----DILCLCSPNNPTGTVLNKDQLRAIVHYAIEHE 202
Query: 199 IYILSDEPYEHFIYDDAKHYPMLKFAPEN--TILANSFSKTFAMTGWRLGFVVAPSE--- 253
I IL D Y FI D + + + I NSFSK G RLG+ V P E
Sbjct: 203 ILILFDAAYSTFISDPSLPKSIFEIPDARFCAIEINSFSKPLGFAGIRLGWTVIPQELTY 262
Query: 254 -----IIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRL 308
+I++ + + + Q AGV L +A+ R+ + RK +L
Sbjct: 263 ADGHFVIQDWERFLSTTFNGASIPAQEAGVAGLSILPQLEAIHYYRENSDLLRKALLAT- 321
Query: 309 KEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRIS 368
G V + A Y++ +S ++ L + + + PG FG+ G G+VR S
Sbjct: 322 ----GFEVFGGEHAPYLWVKPTQANISDRDLFDFFLREYHIAITPGIGFGRSGSGFVRFS 377
Query: 369 YATSREKLMEAMDRMEKA 386
RE ++ A +R++ A
Sbjct: 378 SLGKREDILAACERLQMA 395
>pir||E75208 probable valine--pyruvate transaminase (EC 2.6.1.66) PAB2227
[similarity] - Pyrococcus abyssi (strain Orsay)
>gi|5457625|emb|CAB49116.1| (AJ248283) AMINOTRANSFERASE
[Pyrococcus abyssi]
Length = 410
Score = 116 bits (289), Expect = 3e-25
Identities = 103/399 (25%), Positives = 203/399 (50%), Gaps = 24/399 (6%)
Query: 8 FIAERVILIKRSKIRELFERASKMENVISLGIGEPDFDT-PKNI-KEACKRALDEGWT-- 63
F +++ + +K S++REL + + ++ISL G P+ T PK I KE ++E
Sbjct: 15 FFSKKAMEMKASEVRELLKLV-ETSDIISLAGGLPNPKTFPKEIIKEILIEIMEEHADKA 73
Query: 64 -HYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIP 122
Y G LRE ++++ +K Y + + +++IT+G+ + L ++ GD V++
Sbjct: 74 LQYGTTKGFTPLRETLLDWLEKRYGISKE-NDIMITSGSQQALDLIGRVFIDPGDIVIVE 132
Query: 123 DPAFVSYVEDAKLAEAKPVRIPLREEN-NFMPDPDELLELVTKKTRM-IVINYPN--NPT 178
P +++ ++ E K +++PL + N DEL +L + ++ IV P NP
Sbjct: 133 APTYLAALQAFNFYEPKYIQVPLDDNGMNVEALEDELRKLKAEGKKVKIVYTVPTFQNPA 192
Query: 179 GATLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTIL-ANSFSKT 237
G T+ +E K + ++A +Y++ ++ D+PY Y + E ++ +FSK
Sbjct: 193 GVTMSEERRKHLIELASEYDLIVIEDDPYGELRYSGKPKKKIKALDKEGRVIYLGTFSKI 252
Query: 238 FAMTGWRLGFVVAPSEIIK--EMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRK 295
A G+R+G++V II+ E+ K + NV F QV + + + + ++R+
Sbjct: 253 LA-PGFRIGWIVGDPGIIRKLEIAKQSTDLCTNV--FGQVVAWKYVSEGHLDRHIPKIRE 309
Query: 296 EYNERRKLVLKRLKE-MP-GIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIP 353
Y RR +L+ L+E MP ++ +P+G +V+ ++ D G+ S+K E ++K V +P
Sbjct: 310 FYKPRRDAMLEALEEFMPENVKWTKPEGGMFVWVTLPD-GIDSKKMLEKAVKKG-VAYVP 367
Query: 354 GTAFGKMGE--GYVRISYA-TSREKLMEAMDRMEKALSE 389
G AF + +R+++ +K+ E + R+ + + E
Sbjct: 368 GEAFYAYRDVKNTMRLNFTYVDEDKIREGVKRLAETIKE 406
>sp|Q08432|PATB_BACSU PUTATIVE AMINOTRANSFERASE B >gi|421526|pir||S32934 aminotransferase
patB - Bacillus subtilis >gi|1934779|emb|CAB07910.1|
(Z93933) aminotransferase [Bacillus subtilis]
>gi|1934787|emb|CAB07924.1| (Z93934) aminotransferase
[Bacillus subtilis] >gi|2231218|gb|AAB61979.1| (U63302)
PatB [Bacillus subtilis] >gi|2635640|emb|CAB15133.1|
(Z99120) aminotransferase [Bacillus subtilis]
Length = 387
Score = 115 bits (286), Expect = 7e-25
Identities = 84/382 (21%), Positives = 175/382 (44%), Gaps = 18/382 (4%)
Query: 16 IKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLR 75
+K K ELF + + + + + + DF P+ I EA K LD G YT Q+ +
Sbjct: 15 VKWDKTGELFG----VTDALPMWVADMDFRAPEAITEALKERLDHGIFGYTTPD--QKTK 68
Query: 76 EAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKL 135
+AV + + + ++ E++ + G +A ++ E GD+V++ P + + +
Sbjct: 69 DAVCGWMQNRHGWKVNPESITFSPGVVTALSMAVQAFTEPGDQVVVQPPVYTPFYHMVEK 128
Query: 136 AEAKPVRIPLREENNFMPDPDELLE--LVTKKTRMIVINYPNNPTGATLDKEVAKAIADI 193
+ PL E++ E LE L + ++ P+NP+G + +E + ++
Sbjct: 129 NGRHILHNPLLEKDGAYAIDFEDLETKLSDPSVTLFILCNPHNPSGRSWSREDLLKLGEL 188
Query: 194 AQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPEN---TILANSFSKTFAMTGWRLGFVVA 250
++ + ++SDE + + KH P + + ++ + SKTF + G + ++
Sbjct: 189 CLEHGVTVVSDEIHSDLMLYGHKHTPFASLSDDFADISVTCAAPSKTFNIAGLQASAIII 248
Query: 251 PSEI--IKEMIKLHAYIIGNVASFIQVAGVEALRSEESW--KAVKEMRKEYNERRKLVLK 306
P + K L +G + +F A A W + + + K NE +
Sbjct: 249 PDRLKRAKFSASLQRNGLGGLNAFAVTAIEAAYSKGGPWLDELITYIEKNMNEAEAFLST 308
Query: 307 RLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVR 366
E+P +++ +P ++ ++ G+S + + +L+K +V++ PGT +G GEG++R
Sbjct: 309 ---ELPKVKMMKPDASYLIWLDFSAYGLSDAELQQRMLKKGKVILEPGTKYGPGGEGFMR 365
Query: 367 ISYATSREKLMEAMDRMEKALS 388
++ S L + + R++ ALS
Sbjct: 366 LNAGCSLATLQDGLRRIKAALS 387
>gb|AAD45375.1|AF163863_1 (AF163863) tyrosine aminotransferase [Mustela vison]
Length = 454
Score = 115 bits (286), Expect = 7e-25
Identities = 90/374 (24%), Positives = 169/374 (45%), Gaps = 28/374 (7%)
Query: 32 ENVISLGIGEP----DFDTPKNIKEACKRALDEG-WTHYTPNAGIQQLREAVVEYYKKFY 86
+ +I+L IG+P + T + +A K ALD G + Y P+ G RE + YY +
Sbjct: 71 KTMIALSIGDPTVFGNLPTDPEVTQAMKDALDSGKYNGYAPSIGYLSSREEIASYYHR-P 129
Query: 87 DVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLR 146
+ ++ ++VI+T+G + L L G +L+P P F Y LAE+ + + L
Sbjct: 130 EAPLEAKDVILTSGCSQAIELCLAVLANPGQNILVPRPGFSLY---RTLAESMGIEVKLY 186
Query: 147 E---ENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILS 203
E ++ D +L L+ +KT +++N P+NP G+ + + I +A + IL+
Sbjct: 187 NLLPEKSWEIDLKQLESLIDEKTACLIVNNPSNPCGSVFSRSHLQKILAVAARQCVPILA 246
Query: 204 DEPYEHFIYDDAKHYPMLKFAPENTILA-NSFSKTFAMTGWRLGFV-------VAPSEII 255
DE Y ++ D+ P+ + IL+ +K + + GWRLG++ + +EI
Sbjct: 247 DEIYGDMVFSDSTFEPLATLSSNVPILSCGGLAKRWLVPGWRLGWILIHDRRDIFGNEIR 306
Query: 256 KEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIR 315
++KL I+G I ++++ + L L +PG++
Sbjct: 307 DGLVKLSQRILGPCT--IVQGALKSILHRTPQEFYHNTLSLLKSNADLCYGALAAIPGLQ 364
Query: 316 VKEPKGAFYVFPSIKDTGM----SSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYAT 371
P GA Y+ I+ + +F+E L+ + V +P T F + R+
Sbjct: 365 PVRPSGAMYLMVGIEMEHFPEFENDVEFTERLVAEQSVHCLPATCFEY--PNFFRVVITV 422
Query: 372 SREKLMEAMDRMEK 385
+ ++EA R+++
Sbjct: 423 PKVMMLEACSRIQE 436
>gb|AAF73587.1| (AE002334) aminotransferase, class I [Chlamydia muridarum]
Length = 393
Score = 113 bits (280), Expect = 4e-24
Identities = 104/381 (27%), Positives = 171/381 (44%), Gaps = 27/381 (7%)
Query: 18 RSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRAL-----DEGWTHYTPNAGIQ 72
R++I + F + VI+L IG+ ++ EA +A+ + Y P+ G+
Sbjct: 20 RNRIAQ-FHSENPQHQVINLSIGDTTQPLDTSVAEAFSQAIARFSSPSTYCGYGPDFGLP 78
Query: 73 QLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVED 132
LR+ + E K Y ++ E + I+ GA + S V + DP++ +Y++
Sbjct: 79 SLRQKLSE---KLYHGCVNAEEIFISDGAKVDLFRLL-SFFGPNQIVAVQDPSYPAYIDI 134
Query: 133 AKLAEAKP-VRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIA 191
A+L AK V +P +EN+F+P E + ++ + PNNPTG L+K +AI
Sbjct: 135 ARLTGAKEIVSLPCLQENDFLPVFPENTHI-----DILCLCSPNNPTGTALNKNQLRAIV 189
Query: 192 DIAQDYNIYILSDEPYEHFIYDDAKHYPMLKF-APENTILA---NSFSKTFAMTGWRLGF 247
A ++NI IL D Y FI A P F P+ A NSFSK+ G RLG+
Sbjct: 190 RYAIEHNILILFDAAYSAFI--SAPSLPKSIFEIPDARFCAIEINSFSKSLGFAGIRLGW 247
Query: 248 VVAPSEIIKE----MIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKL 303
V P E+ E +I+ + + + EA + S + E Y E L
Sbjct: 248 TVIPKELTYEDGQPIIRDWKRFLSTTFNGASIPAQEAATAGLSTLSKLEAVHYYKENSHL 307
Query: 304 VLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEG 363
LK G +V + A Y++ + ++ L++ + + PG FG G G
Sbjct: 308 -LKTSLLKAGFQVFGGEHAPYLWVKPTIETVPYRDLFDFFLQEYHIAITPGIGFGLCGSG 366
Query: 364 YVRISYATSREKLMEAMDRME 384
+VR S RE ++ A +R++
Sbjct: 367 FVRFSSLGKREDVLVACERLQ 387
>sp|Q50672|YM94_MYCTU PUTATIVE AMINOTRANSFERASE RV2294 >gi|7447824|pir||B70733 probable
aminotransferase - Mycobacterium tuberculosis (strain
H37RV) >gi|1449326|emb|CAB00976.1| (Z77163) hypothetical
protein Rv2294 [Mycobacterium tuberculosis]
Length = 407
Score = 113 bits (279), Expect = 5e-24
Identities = 93/384 (24%), Positives = 172/384 (44%), Gaps = 34/384 (8%)
Query: 33 NVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYY-KKFYDVDID 91
+V+ L + E D P + +A +RA+D+G T Y + EAV E+ +++ D++
Sbjct: 29 DVLPLWVAEMDVKLPPTVADALRRAIDDGDTGYPYGT---EYAEAVREFACQRWQWHDLE 85
Query: 92 VENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENNF 151
V I G + + GD V++ P + + + + PLR +
Sbjct: 86 VSRTAIVPDVMLGIVEVLRLITDRGDPVIVNSPVYAPFYAFVSHDGRRVIPAPLRGDGRI 145
Query: 152 MPDPDELLELVTKKTRM--------IVINYPNNPTGATLDKEVAKAIADIAQDYNIYILS 203
D D L E + ++ P+NPTG+ + + IA+ AQ + + ++S
Sbjct: 146 --DLDALQEAFSSARASSGSSGNVAYLLCNPHNPTGSVHTADELRGIAERAQRFGVRVVS 203
Query: 204 DEPYEHFIYDDAKHYPMLKF-APENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLH 262
DE + I A+ P L EN S SK + + G + +A E ++ ++
Sbjct: 204 DEIHAPLIPSGARFTPYLSVPGAENAFALMSASKAWNLGGLKAALAIAGREAAADLARMP 263
Query: 263 AYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKE-MPGIRVKEPKG 321
+ + +A A R+ +W + + + + R L+ + E +PG++ + P+G
Sbjct: 264 EEVGHGPSHLGVIAHTAAFRTGGNW--LDALLRGLDHNRTLLGALVDEHLPGVQYRWPQG 321
Query: 322 AFYVFPSIKDTGM---SSEKFSE-------------WLLEKARVVVIPGTAFGKMGEGYV 365
+ + ++ G +S++ +E W L+ ARV + G FG G G+V
Sbjct: 322 TYLAWLDCRELGFDDAASDEMTEGLAVVSDLSGPARWFLDHARVALSSGHVFGIGGAGHV 381
Query: 366 RISYATSREKLMEAMDRMEKALSE 389
RI++ATSR L+EA+ RM ++L E
Sbjct: 382 RINFATSRAILIEAVSRMSRSLLE 405
>pir||H72293 probable valine--pyruvate transaminase (EC 2.6.1.66) TM1131
[similarity] - Thermotoga maritima (strain MSB8)
>gi|4981677|gb|AAD36207.1|AE001770_19 (AE001770)
aminotransferase, putative [Thermotoga maritima]
Length = 413
Score = 111 bits (276), Expect = 1e-23
Identities = 94/395 (23%), Positives = 191/395 (47%), Gaps = 26/395 (6%)
Query: 16 IKRSKIRELFERASKMENVISLGIGEPDFDT--PKNIKEACKRALDEGWTH---YTPNAG 70
+K S IRE+ + A+ ++ IS G G PD +T K + E K +++ + + Y+ G
Sbjct: 16 MKSSIIREILKFAAD-KDAISFGGGVPDPETFPRKELAEIAKEIIEKEYHYTLQYSTTEG 74
Query: 71 IQQLREAVVEYYKKFYDVD-IDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSY 129
L++ +++ ++ Y + +D +N+I T G+ + L + L+ ++ DPA++
Sbjct: 75 DPVLKQQILKLLERMYGITGLDEDNLIFTVGSQQALDLIGKLFLDDESYCVLDDPAYLGA 134
Query: 130 VEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRM-------IVINYPNNPTGATL 182
+ + A V +PL ++ + + L K ++ +V N+ +NP G T
Sbjct: 135 INAFRQYLANFVVVPLEDDGMDLNVLERKLSEFDKNGKIKQVKFIYVVSNF-HNPAGVTT 193
Query: 183 DKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKF-APENTILANSFSKTFAMT 241
E KA+ +IA+ Y+++I+ D+PY Y+ P+ K PE +L N+FSK A
Sbjct: 194 SLEKRKALVEIAEKYDLFIVEDDPYGALRYEGETVDPIFKIGGPERVVLLNTFSKVLA-P 252
Query: 242 GWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERR 301
G R+G V E I+++++ + L + + +K + Y +R
Sbjct: 253 GLRIGMVAGSKEFIRKIVQAKQSADLCSPAITHRLAARYLERYDLLEQLKPTIELYRRKR 312
Query: 302 KLVLKRLKE----MPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAF 357
++L L+E +PG++ + +G +++ ++ + G + + E+ K +V +PG F
Sbjct: 313 TVMLNALEEYFSDIPGVKWVKSEGGLFIWLTLPE-GFDTWEMFEYAKRK-KVFYVPGRVF 370
Query: 358 GKMGE--GYVRISYA-TSREKLMEAMDRMEKALSE 389
E +R+S+ EK++E + R+ + + E
Sbjct: 371 KVYDEPSPSMRLSFCLPPDEKIVEGIKRLREVVLE 405
>emb|CAC12318.1| (AL445066) aspartate aminotransferase related protein [Thermoplasma
acidophilum]
Length = 402
Score = 111 bits (276), Expect = 1e-23
Identities = 102/393 (25%), Positives = 187/393 (46%), Gaps = 27/393 (6%)
Query: 16 IKRSKIRELFERASKMENVISLGIGEPDFDT--PKNIKEACKRALD---EGWTHYTPNAG 70
IK S+IR L + S E +IS G G P+ ++ K +KE +D + Y G
Sbjct: 12 IKPSEIRSLLKYTSDPE-LISFGGGMPNPESFPIKEMKEILNDVIDNYGKKALQYGTTEG 70
Query: 71 IQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYV 130
+ LR+ + +Y +K + E +I+T G+ + Y + G+ V+ P +V +
Sbjct: 71 LDPLRDELAKYVEKTEGIRAKREEIILTTGSQQALYAIGKIFTNPGETVITEGPTYVGAI 130
Query: 131 EDAKLAEAKPVRIPLREENNFMPDPDELLELV-------TKKTRMIVINYPNNPTGATLD 183
+A+ + I L ++ D D L E + TK + VI NP G T+
Sbjct: 131 SAFNSNKAEMIAIDLDDKG---MDVDALEERIRNFMANGTKPKFIYVIPTFQNPAGTTMV 187
Query: 184 KEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPE--NTILANSFSKTFAMT 241
+ K + +I++ Y I I+ D PY Y D P +K + N I +FSK A
Sbjct: 188 LDRRKQLLEISKRYEIPIVEDNPYGQLRY-DGDPVPSIKSMDDDGNVIYLGTFSKVMA-P 245
Query: 242 GWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERR 301
G RLG+V+A +I++++ + + S + E L+ + ++ + + Y ++R
Sbjct: 246 GLRLGYVIADRQIVEKINLVKQGLDLASDSLSEYIAYEYLKRGDIYRQIPKTVSLYRKKR 305
Query: 302 KLVLKRLKEM--PGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGK 359
L+LK + E G++ +P G +++ S+ D + + + E L KA+V + G AF
Sbjct: 306 DLMLKSIAEYFPEGVKYTKPNGGMFLWVSL-DEKIDTTRMLERAL-KAKVAYVSGAAFYP 363
Query: 360 MGEGY--VRISYATS-REKLMEAMDRMEKALSE 389
GE + +R+++ S +K++E + R+ ++E
Sbjct: 364 HGEKHNSMRLNFTYSDDDKIVEGIKRLAYVINE 396
>dbj|BAA86884.1| (AB027131) multiple substrate aminotransferase (MsAT) [Thermococcus
profundus]
Length = 417
Score = 111 bits (275), Expect = 1e-23
Identities = 96/397 (24%), Positives = 192/397 (48%), Gaps = 19/397 (4%)
Query: 8 FIAERVILIKRSKIRELFERASKMENVISL--GIGEPDFDTPKNIKEACKRALDEGWT-- 63
F +E+ +L+K S++REL + + +VISL G+ P+ + IK+ L+E
Sbjct: 18 FFSEKAMLMKASEVRELLKLV-ETSDVISLAGGLPAPETFPVETIKKIAVEVLEEHADKA 76
Query: 64 -HYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIP 122
Y G LR A+ + +K YD+ + ++ AG+ + L L GD +++
Sbjct: 77 LQYGTTKGFTPLRLALARWMEKRYDIPMSKVEIMTVAGSQQALDLIGRVFLNPGDPIVVE 136
Query: 123 DPAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYP----NNPT 178
P +++ ++ K + + + IPL ++ + +E LE + K+ + + I Y NP
Sbjct: 137 APTYLAAIQAFKYYDPEFISIPLDDKGMRVDLLEEKLEELRKQGKRVKIVYTVSTFQNPA 196
Query: 179 GATLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTIL-ANSFSKT 237
G T+ + K + ++A +Y+ I+ D PY Y P+ F ++ +FSK
Sbjct: 197 GVTMSVDRRKKLLELANEYDFLIVEDGPYSELRYSGEPTPPIKHFDDYGRVIYLGTFSKI 256
Query: 238 FAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEY 297
A G+R+G+V A +I++M I +F Q + + + + + ++ + Y
Sbjct: 257 LA-PGFRIGWVAAHPHLIRKMEIAKQSIDLCTNTFGQAIAWKYVENGYLDEHIPKIIEFY 315
Query: 298 NERRKLVLKRLKE-MP-GIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGT 355
RR +L+ L+E MP G+ +P+G +V+ ++ + G+ ++ E + K V +PG
Sbjct: 316 KPRRDAMLEALEEYMPEGVEWTKPEGGMFVWVTLPE-GIDTKLMMERAVAKG-VAYVPGE 373
Query: 356 AF--GKMGEGYVRISYA-TSREKLMEAMDRMEKALSE 389
AF + + +R+++ E + E + R+ + + E
Sbjct: 374 AFFVHRDKKNTMRLNFTYVPEETIREGVRRLAETIKE 410
>gb|AAF86990.1|AF282249_9 (AF282249) ArcT [Lactococcus lactis subsp. lactis]
Length = 376
Score = 109 bits (271), Expect = 4e-23
Identities = 83/342 (24%), Positives = 150/342 (43%), Gaps = 18/342 (5%)
Query: 50 IKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAF 109
+ + K GW +P + V + YK+ + +N++ T GA +L
Sbjct: 48 MSQMMKEKFSYGWIEGSP-----AFKSEVAKLYKR-----VSEDNILSTNGATGANFLTI 97
Query: 110 ESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMI 169
L+ GD V+ P++ + K A+ ++EEN+++P ++L LV T++I
Sbjct: 98 LGLIGQGDHVIAQYPSYQQLYDCPKTLGAQVDYWKIKEENHWLPQIEDLRRLVKPNTKLI 157
Query: 170 VINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTI 229
+N PTGA + + + +IA+ + YIL DE Y D+ Y + E I
Sbjct: 158 CLNNAAQPTGAIMSPDFLAEVVEIARSVDAYILCDEVY--LPLDEETPYAPIADLYEKGI 215
Query: 230 LANSFSKTFAMTGWRLGFVVAPS-EIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWK 288
NS SKT+++ G R+G+V ++ E K+ Y + F L+ ++ K
Sbjct: 216 STNSISKTYSVPGIRVGWVATQDRDLCNEFRKIRDYTLICTGVFDDALASLVLKHKD--K 273
Query: 289 AVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTG-MSSEKFSEWLLEKA 347
+ R ++ + ++ P + + P F + M +E F+ LL +
Sbjct: 274 VLARARDIVKGNLSILKEWVENEPLVSMVYPNAVSVSFVKFEQLDPMKTEDFAIQLLREK 333
Query: 348 RVVVIPGTAFGKMGEGYVRISYATSREKLMEAMDRMEKALSE 389
V++IPG F GY RI Y T ++ L + + + + L E
Sbjct: 334 GVLIIPGNRFDL--PGYARIGYCTDKKTLRQGLQLLSEFLRE 373
>gb|AAF48363.1| (AE003495) CG1461 gene product [Drosophila melanogaster]
Length = 501
Score = 109 bits (270), Expect = 5e-23
Identities = 97/399 (24%), Positives = 173/399 (43%), Gaps = 37/399 (9%)
Query: 12 RVILIKRSKIRELFERASKMEN----VISLGIGEPD-FDTPKNIKEACK---RALDEG-W 62
++ L ++IR + E N +I L IG+P F K E K +L+ G +
Sbjct: 85 KLSLNTHNRIRNIVESLKIKPNPEKPMIPLSIGDPTTFGNLKAADETMKAVLHSLESGKY 144
Query: 63 THYTPNAGIQQLREAVVEYYK-KFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLI 121
Y G + R+AV +Y + D +ID V++ +G +L + G VL+
Sbjct: 145 NGYASTQGHEIARKAVAKYSAHQRPDGEIDANEVVLCSGCSSALEYCILALADRGQNVLV 204
Query: 122 PDPAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGAT 181
P P F Y A+ + + L + + D +L L+ + T ++IN P+NP G+
Sbjct: 205 PRPGFCLYYTLAQGLDIEVRYYDLLPDQQWRADLVQLESLIDENTAALLINNPSNPCGSV 264
Query: 182 LDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILA-NSFSKTFAM 240
D++ + + I + + + I++DE YEHF++ +KH + E +L+ +K F +
Sbjct: 265 FDEKHLRELIAICERHYLPIIADEIYEHFVFPGSKHLAVSSLTTEVPVLSCGGLTKRFLV 324
Query: 241 TGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEY--- 297
GWR+G+++ + +L I+G ++ G + + + + Y
Sbjct: 325 PGWRMGWII----VHDRKNRLRDAIVGLKNMCGRILGSNTIIQGALPDILTKTPQSYFDG 380
Query: 298 -----NERRKLVLKRLKEMPGIRVKEPKGAFYV--------FPSIKDTGMSSEKFSEWLL 344
+ L K LK++ G+ P GA Y+ FP KD F + ++
Sbjct: 381 VIDVLHSNAMLAYKMLKQVRGLDPVMPNGAMYMMIGVSIERFPEFKD----DTHFVQEMV 436
Query: 345 EKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAMDRM 383
+ V +PG+ F GYVRI + EA R+
Sbjct: 437 NEQSVFCLPGSCFEY--PGYVRIVLTVPGAMIEEACSRI 473
>gi|11499606 histidinol-phosphate aminotransferase (hisC-2) [Archaeoglobus
fulgidus] >gi|7450423|pir||G69502 histidinol-phosphate
aminotransferase (hisC-2) homolog - Archaeoglobus
fulgidus >gi|2648510|gb|AAB89229.1| (AE000963)
histidinol-phosphate aminotransferase (hisC-2)
[Archaeoglobus fulgidus]
Length = 342
Score = 108 bits (268), Expect = 9e-23
Identities = 104/369 (28%), Positives = 182/369 (49%), Gaps = 43/369 (11%)
Query: 24 LFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYK 83
LF + V++L E ++ + ++EA RA+ + P A +L++A+ EY
Sbjct: 15 LFPEDFPDKEVVNLSSNENPYEPSEEVREAYLRAVK--YIPRYPKADYARLKKALAEY-- 70
Query: 84 KFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRI 143
+VEN+ + GA E LLE D V+IP P++ Y A L A +
Sbjct: 71 ----TGFEVENIAVGCGASELISCICNVLLEELDRVVIPMPSYTLYSIYAMLRSAS-ISF 125
Query: 144 PLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILS 203
P+ E + DPD + E ++ +++ + PNNPTG +L +E+ + +A+ A+ Y++
Sbjct: 126 PVFE--GYRVDPDVIAE---ERPKLVFLCSPNNPTGNSLSREIVQKVAESAE----YVVL 176
Query: 204 DEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHA 263
DE Y F DD+K + + N I+ SFSK F + G R+G+ V +EI + + K+
Sbjct: 177 DEAYVEFS-DDSKIEMVRDY--NNLIVLRSFSKFFGLAGMRVGYAVCSAEIAEAIEKVR- 232
Query: 264 YIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAF 323
G ++ A + ALRS + +K V++ + ER +L+ ++LKE+ + V P A
Sbjct: 233 LPFGISYPAVETA-IAALRSLDYYKKVRD--RIVRERERLI-EKLKEIEWLEV-YPSDAN 287
Query: 324 YVFPSIKDTGMSSEKFSE--WLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAMD 381
+V G+ EK +E +++ A V+ + G Y+RI+ + D
Sbjct: 288 FVLVKANKEGV-VEKLAEKGFIVRDASVMGLEGL--------YIRITVGKREDN-----D 333
Query: 382 RMEKALSEL 390
R+ +AL E+
Sbjct: 334 RLIEALREI 342
>pir||T04985 probable transaminase (EC 2.6.1.-) T16L1.170 [similarity] -
Arabidopsis thaliana >gi|3549670|emb|CAA20581.1|
(AL031394) putative protein [Arabidopsis thaliana]
>gi|7270317|emb|CAB80085.1| (AL161584) putative protein
[Arabidopsis thaliana]
Length = 426
Score = 108 bits (268), Expect = 9e-23
Identities = 107/381 (28%), Positives = 174/381 (45%), Gaps = 44/381 (11%)
Query: 34 VISLGIGE-----PDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYD- 87
VISLGIG+ P+ T K+A + + EG++ Y G + LR A+ K FY
Sbjct: 58 VISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIA---KTFYGG 114
Query: 88 VDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDA-------------- 133
+ I ++V ++ GA + + + S + + DP++ +YV+ +
Sbjct: 115 LGIGDDDVFVSDGA-KCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQ 173
Query: 134 KLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADI 193
K + +R EN F PD + +T +I PNNPTGA +E + +
Sbjct: 174 KYGNIEYMRCT--PENGFFPDLSTV-----GRTDIIFFCSPNNPTGAAATREQLTQLVEF 226
Query: 194 AQDYNIYILSDEPYEHFIYDD-AKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPS 252
A+ I+ D Y ++ DD + + A E + SFSK TG RLG+ V P
Sbjct: 227 AKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPK 286
Query: 253 EII--------KEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLV 304
+++ K+ ++ N AS I AG A + E +A+ ++ Y E ++
Sbjct: 287 KLLYSDGFPVAKDFNRIICTCF-NGASNISQAGALACLTPEGLEAMHKVIGFYKENTNII 345
Query: 305 LKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGY 364
+ + G V K A YV+ + S + F+E +LEK VV PG+ FG GEG+
Sbjct: 346 IDTFTSL-GYDVYGGKNAPYVWVHFPNQS-SWDVFAE-ILEKTHVVTTPGSGFGPGGEGF 402
Query: 365 VRISYATSREKLMEAMDRMEK 385
VR+S RE ++EA R ++
Sbjct: 403 VRVSAFGHRENILEACRRFKQ 423
>pir||F72072 probable transaminase (EC 2.6.1.-) aspC [similarity] -
Chlamydophila pneumoniae (strain CWL029)
>gi|4376781|gb|AAD18635.1| (AE001634) Aspartate
Aminotransferase [Chlamydophila pneumoniae CWL029]
>gi|8163398|gb|AAF73649.1| (AE002186) aminotransferase,
class I [Chlamydophila pneumoniae AR39]
>gi|8978865|dbj|BAA98701.1| (AP002546) aspartate
aminotransferase [Chlamydophila pneumoniae J138]
Length = 397
Score = 108 bits (268), Expect = 9e-23
Identities = 100/384 (26%), Positives = 172/384 (44%), Gaps = 37/384 (9%)
Query: 19 SKIRELFERASKMENVISLGIGEPDFDTPKNIKEACK-----RALDEGWTHYTPNAGIQQ 73
SK F + + +VI L IG+ ++I +A K + E + Y P G+++
Sbjct: 20 SKKLAQFRKENPEISVIDLSIGDTTQPLCRSITQAIKEFCVSQEKQETYRGYGPETGLEK 79
Query: 74 LREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDA 133
LR + + Y+ I E + I+ GA + F S S + + DP + +Y + A
Sbjct: 80 LRTKIAS---EVYENRISPEEIFISDGAKPDIFRLF-SFFGSEKTLGLQDPVYPAYRDIA 135
Query: 134 KLAEAKPVRIPL--REENNFMPD-PDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAI 190
+ + + IPL R+E F+P+ P++ + ++ + YPNNPTG L + +A+
Sbjct: 136 HITGIRDI-IPLACRKETGFIPELPNQ------QSLDILCLCYPNNPTGTVLTFQQLQAL 188
Query: 191 ADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILA---NSFSKTFAMTGWRLGF 247
+ A + ++ D Y F+ D + + + PE A NSFSK+ TG RL +
Sbjct: 189 VNYANQHGTVLIFDAAYSAFVSDPSLPKSIFEI-PEAKYCAIEINSFSKSLGFTGMRLAW 247
Query: 248 VVAPSEI--------IKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNE 299
V P E+ I + +L A + +Q AG L + A+ +
Sbjct: 248 NVIPKELTYDNNEPMINDWKRLFATTFNGASLLMQEAGYYGLDLFPTPPAISLYLTNAQK 307
Query: 300 RRKLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGK 359
LK+ E G V A Y++ + + G+S E+ ++ L + + V PG FG
Sbjct: 308 -----LKKSLETAGFSVHGGDHAPYLWVELPE-GISDEEAFDFFLHQYHIAVTPGHGFGS 361
Query: 360 MGEGYVRISYATSREKLMEAMDRM 383
G+G+VR S T + + A DR+
Sbjct: 362 CGQGFVRFSALTQPQNIALACDRL 385
>gb|AAK40904.1| Histidinol-phosphate aminotransferase (hisC) [Sulfolobus
solfataricus]
Length = 376
Score = 107 bits (264), Expect = 3e-22
Identities = 97/383 (25%), Positives = 182/383 (47%), Gaps = 52/383 (13%)
Query: 18 RSKIRELFERASK-----MENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQ 72
R+KI+ AS+ ++ I L + E F+ P+ I +A K L +G + P+ ++
Sbjct: 27 RNKIKSWLLNASEYDFTDIKEGIRLHLNESPFEPPQFIIDAVKMYLSKGNRYQHPDL-LE 85
Query: 73 QLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVED 132
+ RE EY K ++ EN+ + GA F +L+E GD +L P++ Y
Sbjct: 86 KYRELAAEYSK------VEPENIYPSVGADGSIRAIFYNLVEPGDTILTNYPSYSMYSVY 139
Query: 133 AKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIAD 192
+ + K +++ L+E+N + + + L +K +++I+ PNNPTG+ + + I
Sbjct: 140 SSVRGTKVIKVNLKEDNEWWKENTDDLLAQAEKVELVIIDDPNNPTGSPMLNGKKELIGQ 199
Query: 193 IAQDYNIYILSDEPYEHF--------IYDDAKHYPMLKFAPENTILANSFSKTFAMTGWR 244
+A++ +++ DE Y F IYD YP N ++ + SK F++ +R
Sbjct: 200 LAENTKGFVVIDEAYYEFGGYTVSPYIYD----YP-------NVLVVRTLSKAFSLASYR 248
Query: 245 LGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLV 304
LG+ +A EI+K ++K + S I AG+ AL E+ +K++ N R+++
Sbjct: 249 LGYTIANEEIVKALMKSSTPFDIPLPSLI--AGITAL---ENPSYIKDVVNIVNRNREIL 303
Query: 305 LKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGY 364
+ LK + ++V + F + IKD + E L+ G A K+ + +
Sbjct: 304 YQGLKNL-NLKVYKSITNFLL---IKD----NRNLQEMLMRH-------GIAIRKLYDNF 348
Query: 365 VRISYATSREKLMEAMDRMEKAL 387
RI+ T + M +D++ + L
Sbjct: 349 YRITIGTEDQCKM-VIDKLGEEL 370
>sp|O33770|HIS8_SULSO HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMIDAZOLE ACETOL-PHOSPHATE
TRANSAMINASE) >gi|2253619|gb|AAB63018.1| (U82227)
imidazole acetol phosphate aminotransferase [Sulfolobus
solfataricus] >gi|6015881|emb|CAB57708.1| (Y18930) HisC
(imidazole acetol phosphate aminotransferase)
[Sulfolobus solfataricus]
Length = 376
Score = 107 bits (264), Expect = 3e-22
Identities = 97/383 (25%), Positives = 182/383 (47%), Gaps = 52/383 (13%)
Query: 18 RSKIRELFERASK-----MENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQ 72
R+KI+ AS+ ++ I L + E F+ P+ I +A K L +G + P+ ++
Sbjct: 27 RNKIKSWLLNASEYDFTDIKEGIRLHLNESPFEPPQFIIDAVKMYLSKGNRYQHPDL-LE 85
Query: 73 QLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVED 132
+ RE EY K ++ EN+ + GA F +L+E GD +L P++ Y
Sbjct: 86 KYRELAAEYSK------VEPENIYPSVGADGSIRAIFYNLVEPGDTILTNYPSYSMYSVY 139
Query: 133 AKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIAD 192
+ + K +++ L+E+N + + + L +K +++I+ PNNPTG+ + + I
Sbjct: 140 SSVRGTKVIKVNLKEDNEWWKENTDDLLAQAEKVELVIIDDPNNPTGSPMLNGKKELIGQ 199
Query: 193 IAQDYNIYILSDEPYEHF--------IYDDAKHYPMLKFAPENTILANSFSKTFAMTGWR 244
+A++ +++ DE Y F IYD YP N ++ + SK F++ +R
Sbjct: 200 LAENTKGFVVIDEAYYEFGGYTVSPYIYD----YP-------NVLVVRTLSKAFSLASYR 248
Query: 245 LGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLV 304
LG+ +A EI+K ++K + S I AG+ AL E+ +K++ N R+++
Sbjct: 249 LGYTIANEEIVKALMKSSTPFDIPLPSLI--AGITAL---ENPSYIKDVVNIVNRNREIL 303
Query: 305 LKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGY 364
+ LK + ++V + F + IKD + E L+ G A K+ + +
Sbjct: 304 YQGLKNL-NLKVYKSITNFLL---IKD----NRNLQEMLMRH-------GIAIRKLYDNF 348
Query: 365 VRISYATSREKLMEAMDRMEKAL 387
RI+ T + M +D++ + L
Sbjct: 349 YRITIGTEDQCKM-VIDKLGEEL 370
>pir||F72772 probable valine--pyruvate transaminase (EC 2.6.1.66) APE0169
[similarity] - Aeropyrum pernix (strain K1)
>gi|5103559|dbj|BAA79080.1| (AP000058) 407aa long
hypothetical aminotransferase [Aeropyrum pernix]
Length = 407
Score = 104 bits (257), Expect = 2e-21
Identities = 93/396 (23%), Positives = 182/396 (45%), Gaps = 32/396 (8%)
Query: 17 KRSKIRELFERASKMENVISLGIGEPD---------FDTPKNI-KEACKRALDEGWTHYT 66
+ S +REL + ++ + VIS G PD D +N+ E +AL Y+
Sbjct: 20 RASDVRELL-KLTEGKRVISFAGGLPDPRVFPAEELADIARNVVSELGDKALQ-----YS 73
Query: 67 PNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAF 126
P G+ RE + + ++ + +++T G+ E +L S L GD V++ +P +
Sbjct: 74 PTPGVSIFRERALSFLERM-GLKTSDRQLLVTTGSQEALFLTALSTLSPGDVVIMEEPGY 132
Query: 127 VSYVEDAKLAEAKPVRIPLREEN---NFMPDPDELLELVTKKTRMIVINYP-NNPTGATL 182
++ + K A+ V +P+ ++ + + + L+ K +++ N NNP G T+
Sbjct: 133 LAAINVFKALGARIVPVPVDDKGLNTGVLAETLDRLDAEGVKPKLVYTNPTCNNPNGTTM 192
Query: 183 DKEVAKAIADIAQDYNIYILSDEPYEHFIYD-DAKHYPMLKFAPENTIL-ANSFSKTFAM 240
+ + + +A +Y++ ++ D+PY H ++ + P+ E ++ +FSK A
Sbjct: 193 PLDRRRELLQLASNYDMLVIEDDPYSHIAFEKTGEEVPLQALDSEGRVVYVTTFSKILA- 251
Query: 241 TGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNER 300
G RLG +APSE+ + L + + ++ Q EAL K + Y +
Sbjct: 252 PGLRLGLTLAPSEVTARIELLKQIVDLHTSTLDQYIAAEALERGIVDKVISRAVSIYRRK 311
Query: 301 RKLVLKRLKE-MPGIRV-KEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAF- 357
R ++++ L+E M G+ +P G F++F I + +E+ V +PG AF
Sbjct: 312 RDIMIESLEENMSGVATWTKPIGGFFIFLRINGP-VDMRALMPKAVERG-VAYVPGDAFH 369
Query: 358 --GKMGEGYVRISYA-TSREKLMEAMDRMEKALSEL 390
G R+SY+ + E++ E + + K + E+
Sbjct: 370 VTPGAGRNTARLSYSFNTEEEIPEGISILSKLVKEV 405
>pir||T46744 probable transaminase arcT [imported] - Lactobacillus sakei
>gi|2764614|emb|CAA04685.1| (AJ001330) orfT
[Lactobacillus sakei]
Length = 371
Score = 104 bits (256), Expect = 2e-21
Identities = 85/327 (25%), Positives = 151/327 (45%), Gaps = 18/327 (5%)
Query: 64 HYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPD 123
+Y G + ++AV E Y+ ++ V+ T GA LA +L++ G+ V+
Sbjct: 57 NYGAIEGSEAFKQAVSELYQT-----VNSNQVLQTNGATGANLLALYALVKPGNHVITMF 111
Query: 124 PAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLD 183
P + E A L E+NN++PD EL +L+ +T++I +N NNPTG +
Sbjct: 112 PTYQQLYEIPISIGATVSYWQLDEDNNWVPDIAELKKLIRPETKLICLNNANNPTGTVIS 171
Query: 184 KEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGW 243
E+ +AI ++A+ Y+L DE Y + + + E I NS SKT+++ G
Sbjct: 172 TELMQAIVEVARTVGAYVLVDEVY--LPLGEGQQTTSIADLYELGIATNSLSKTYSVPGI 229
Query: 244 RLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKL 303
R+G++VA + K Y + F V L++ + A ++N ++
Sbjct: 230 RVGWLVANETLTDLFRKYRDYTMICAGVFSDQLAVYVLQNRKQVLARNRALVQHN--LEI 287
Query: 304 VLKRLKEMPGIRVKEPKG---AFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKM 360
+ + P + V P+ +F F I+D E F ++LL++ V+++PG F
Sbjct: 288 FKAWVAQEPLVDVVYPESVSTSFIHFKEIED----DEAFCKYLLKEYGVLLVPGKRFEI- 342
Query: 361 GEGYVRISYATSREKLMEAMDRMEKAL 387
G+ R+ Y L + + + KAL
Sbjct: 343 -PGHARLGYCAPEATLKKGLAELSKAL 368
>pir||D70849 probable aminotransferase - Mycobacterium tuberculosis (strain
H37RV) >gi|2808732|emb|CAA16256.1| (AL021428)
hypothetical protein Rv0075 [Mycobacterium tuberculosis]
Length = 390
Score = 103 bits (255), Expect = 3e-21
Identities = 90/371 (24%), Positives = 169/371 (45%), Gaps = 23/371 (6%)
Query: 33 NVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYDVDIDV 92
+V+ L + E DF T + + + +D Y P G L A ++ ++ Y
Sbjct: 28 DVVPLWLAEMDFPTAPAVLDGVRACVDNEEFGYPP-LGEDSLPRATADWCRQRYGWCPRP 86
Query: 93 ENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENN-- 150
+ V + +G + E L V +P PA++ + + + + V +P+ ++++
Sbjct: 87 DWVRVVPDVLKGMEVVVEFLTRPESPVALPVPAYMPFFDVLHVTGRQRVEVPMVQQDSGR 146
Query: 151 FMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHF 210
++ D D L + ++I PNNP G + +AI DIA + +++DE +
Sbjct: 147 YLLDLDALQAAFVRGAGSVIICNPNNPLGTAFTEAELRAIVDIAARHGARVIADEIWAPV 206
Query: 211 IYDDAKHY---PMLKFAPENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIG 267
+Y ++H + + A E + S SK GW L ++ I+ H +
Sbjct: 207 VY-GSRHVAAASVSEAAAEVVVTLVSASK-----GWNLPGLMCAQVILSNRRDAHDWDRI 260
Query: 268 NV-----ASFIQV-AGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEM-PGIRVKEPK 320
N+ AS + + A + A ESW + E+ R + + L E+ PG+ V P
Sbjct: 261 NMLHRMGASTVGIRANIAAYHHGESW--LDELLPYLRANRDHLARALPELAPGVEVNAPD 318
Query: 321 GAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFG-KMGEGYVRISYATSREKLMEA 379
G + + + + SE +E+LL KA+V + PG FG +G G+ R+++AT+R L A
Sbjct: 319 GTYLSWVDFRALALPSEP-AEYLLSKAKVALSPGIPFGAAVGSGFARLNFATTRAILDRA 377
Query: 380 MDRMEKALSEL 390
++ + AL ++
Sbjct: 378 IEAIAAALRDI 388
>gb|AAA85439.1| (U30249) hemolysin [Treponema denticola]
Length = 399
Score = 100 bits (247), Expect = 3e-20
Identities = 87/371 (23%), Positives = 162/371 (43%), Gaps = 24/371 (6%)
Query: 34 VISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYDVDIDVE 93
V+ L + + +F P + E K+ LDE YT ++ ++ V ++ K + DI+ +
Sbjct: 33 VVPLSVADMEFKNPPELIEGLKKYLDETVLGYT--GPTEEYKKTVKKWMKDRHQWDIETD 90
Query: 94 NVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENNFMP 153
+I TAG + A + GD V+I P + + K E K + L E++ +
Sbjct: 91 WIINTAGVVPAVFNAVREFTKPGDGVIIITPVYYPFFMAIKNQERKIIECELLEKDGYYT 150
Query: 154 DPDELLELVTK--KTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDE------ 205
E LE ++K + ++ P+NP G K+ + I DI ++ + SDE
Sbjct: 151 IDFEKLEKLSKDKNNKALLFCSPHNPVGRVWKKDELQKIKDIVLKSDLMLWSDEIHFDLI 210
Query: 206 --PYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHA 263
YEH ++ + TI + SKTF + G + ++ + I+E
Sbjct: 211 MPGYEHTVFQSIDEQ-----LADKTITFTAPSKTFNIAGMGMSNIIIKNPDIRERFTKSR 265
Query: 264 YIIGNVASFIQVAGVEALRS--EESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEP-- 319
I + G +A +E K + K ++ +++V K E+ +K P
Sbjct: 266 DITSGMP--FTTLGYKACEICYKECGKWLDGCIKVIDKNQRIV-KDFFEVNHPEIKAPLI 322
Query: 320 KGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEA 379
+G + + + M + E+++ KA++ G FG G G+ RI+ A + E+
Sbjct: 323 EGTYLQWIDFRALKMDHKAMEEFMIHKAQIFFDEGYIFGDGGIGFERINLAAPSSVIQES 382
Query: 380 MDRMEKALSEL 390
++R+ KAL +L
Sbjct: 383 LERLNKALKDL 393
>pdb|1C7N|A Chain A, Crystal Structure Of Cystalysin From Treponema Denticola
Contains A Pyridoxal 5'-Phosphate Cofactor
>gi|9955070|pdb|1C7N|B Chain B, Crystal Structure Of
Cystalysin From Treponema Denticola Contains A Pyridoxal
5'-Phosphate Cofactor >gi|9955071|pdb|1C7N|C Chain C,
Crystal Structure Of Cystalysin From Treponema Denticola
Contains A Pyridoxal 5'-Phosphate Cofactor
>gi|9955072|pdb|1C7N|D Chain D, Crystal Structure Of
Cystalysin From Treponema Denticola Contains A Pyridoxal
5'-Phosphate Cofactor >gi|9955073|pdb|1C7N|E Chain E,
Crystal Structure Of Cystalysin From Treponema Denticola
Contains A Pyridoxal 5'-Phosphate Cofactor
>gi|9955074|pdb|1C7N|F Chain F, Crystal Structure Of
Cystalysin From Treponema Denticola Contains A Pyridoxal
5'-Phosphate Cofactor >gi|9955075|pdb|1C7N|G Chain G,
Crystal Structure Of Cystalysin From Treponema Denticola
Contains A Pyridoxal 5'-Phosphate Cofactor
>gi|9955076|pdb|1C7N|H Chain H, Crystal Structure Of
Cystalysin From Treponema Denticola Contains A Pyridoxal
5'-Phosphate Cofactor >gi|9955077|pdb|1C7O|A Chain A,
Crystal Structure Of Cystalysin From Treponema Denticola
Contains A Pyridoxal
5'-Phosphate-L-Aminoethoxyvinylglycine Complex
>gi|9955078|pdb|1C7O|B Chain B, Crystal Structure Of
Cystalysin From Treponema Denticola Contains A Pyridoxal
5'-Phosphate-L-Aminoethoxyvinylglycine Complex
>gi|9955079|pdb|1C7O|C Chain C, Crystal Structure Of
Cystalysin From Treponema Denticola Contains A Pyridoxal
5'-Phosphate-L-Aminoethoxyvinylglycine Complex
>gi|9955080|pdb|1C7O|D Chain D, Crystal Structure Of
Cystalysin From Treponema Denticola Contains A Pyridoxal
5'-Phosphate-L-Aminoethoxyvinylglycine Complex
>gi|9955081|pdb|1C7O|E Chain E, Crystal Structure Of
Cystalysin From Treponema Denticola Contains A Pyridoxal
5'-Phosphate-L-Aminoethoxyvinylglycine Complex
>gi|9955082|pdb|1C7O|F Chain F, Crystal Structure Of
Cystalysin From Treponema Denticola Contains A Pyridoxal
5'-Phosphate-L-Aminoethoxyvinylglycine Complex
>gi|9955083|pdb|1C7O|G Chain G, Crystal Structure Of
Cystalysin From Treponema Denticola Contains A Pyridoxal
5'-Phosphate-L-Aminoethoxyvinylglycine Complex
>gi|9955084|pdb|1C7O|H Chain H, Crystal Structure Of
Cystalysin From Treponema Denticola Contains A Pyridoxal
5'-Phosphate-L-Aminoethoxyvinylglycine Complex
Length = 399
Score = 97.1 bits (238), Expect = 3e-19
Identities = 86/370 (23%), Positives = 162/370 (43%), Gaps = 22/370 (5%)
Query: 34 VISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYDVDIDVE 93
V+ L + + +F P + E K+ LDE YT ++ ++ V ++ K + DI +
Sbjct: 33 VVPLSVADMEFKNPPELIEGLKKYLDETVLGYT--GPTEEYKKTVKKWMKDRHQWDIQTD 90
Query: 94 NVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENNFMP 153
+I TAG + A + GD V+I P + + K E K + L E++ +
Sbjct: 91 WIINTAGVVPAVFNAVREFTKPGDGVIIITPVYYPFFMAIKNQERKIIECELLEKDGYYT 150
Query: 154 DPDELLELVTK--KTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDE------ 205
+ LE ++K + ++ P+NP G K+ + I DI ++ + SDE
Sbjct: 151 IDFQKLEKLSKDKNNKALLFCSPHNPVGRVWKKDELQKIKDIVLKSDLMLWSDEIHFDLI 210
Query: 206 --PYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMI-KLH 262
YEH ++ + TI + SKTF + G + ++ + I+E K
Sbjct: 211 MPGYEHTVFQSIDEQ-----LADKTITFTAPSKTFNIAGMGMSNIIIKNPDIRERFTKSR 265
Query: 263 AYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEP--K 320
G + + E + +E K + K ++ +++V K E+ +K P +
Sbjct: 266 DATSGMPFTTLGYKACE-ICYKECGKWLDGCIKVIDKNQRIV-KDFFEVNHPEIKAPLIE 323
Query: 321 GAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAM 380
G + + + M + E+++ KA++ G FG G G+ RI+ A + E++
Sbjct: 324 GTYLQWIDFRALKMDHKAMEEFMIHKAQIFFDEGYIFGDGGIGFERINLAAPSSVIQESL 383
Query: 381 DRMEKALSEL 390
+R+ KAL +L
Sbjct: 384 ERLNKALKDL 393
>pir||F64484 probable transaminase (EC 2.6.1.-) MJ1479 [similarity] -
Methanococcus jannaschii >gi|2826418|gb|AAB99491.1|
(U67589) putative aminotransferase [Methanococcus
jannaschii]
Length = 432
Score = 96.7 bits (237), Expect = 4e-19
Identities = 97/415 (23%), Positives = 179/415 (42%), Gaps = 47/415 (11%)
Query: 20 KIRELFERASKME----NVISLGIGEP---DFDTPKNIKEACKRALDEGWTH-YTPNAGI 71
+IRE+ + A K+E N+ IG+P P IK+ + ++ Y P G+
Sbjct: 16 EIREIVDVAKKIEEFGINITWENIGDPVAKGEKIPDWIKDIIAEIVKNDCSYAYCPTKGL 75
Query: 72 QQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVE 131
+ RE + E K V I E++I G + + LL+ V+ P P++ ++
Sbjct: 76 LETREFLAEQVNKRGGVQITAEDIIFFNGLGDAIAKIY-GLLKRQVRVINPSPSYSTHSS 134
Query: 132 -DAKLAEAKPVRIPLREENNFMPDPDELLELVTKK---TRMIVINYPNNPTGATLDKEVA 187
+A A + PV L N + PD D+L + + + ++VIN P+NPTGA K++
Sbjct: 135 AEASHAGSPPVTYFLDPYNYWYPDIDDLEKRIKYNPAVSGILVIN-PDNPTGAVYPKKIL 193
Query: 188 KAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILA-NSFSKTFAMTGWRLG 246
I D+A +Y+++I+ DE Y + +Y+ K + + + + L+ SK G R G
Sbjct: 194 NEIVDLANEYDLFIICDEIYCNLVYNGKKQHLLCEVIDDVCGLSLKGISKELPWPGARCG 253
Query: 247 FV----VAPSEIIKEMIK--LHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNER 300
++ E K+ ++ A +I ++ + + + ++K E R + E+
Sbjct: 254 WIEIYNADKDEEFKKYVESIYKAKLIEVCSTTLPQMAIPRIMGHRNYKKYLEERNRFFEK 313
Query: 301 R-KLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMS------------------------ 335
R K+LK++ G+ + GAFY+ +D ++
Sbjct: 314 RSNTAYKKLKDLDGVIANKANGAFYMSVVFEDNYLNGNNSIKIENEKLKEFIEHQIKDAS 373
Query: 336 -SEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAMDRMEKALSE 389
+KF +LL + V+P T+F G+ EK D + + + E
Sbjct: 374 IDKKFVYYLLASTGICVVPLTSFCSQLNGFRVTLLERDDEKFEWIFDTLAEKIDE 428
>gb|AAG10013.1| (AF279917) aspartate aminotransferase [Azospirillum brasilense]
Length = 417
Score = 96.7 bits (237), Expect = 4e-19
Identities = 97/378 (25%), Positives = 150/378 (39%), Gaps = 36/378 (9%)
Query: 35 ISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFY---DVDID 91
I + +GEP P I E RA W Y P G + REAV + + Y D D
Sbjct: 50 IMMSVGEPQHQPPAIIDETL-RANAHLWGKYPPVGGTPEFREAVGAWLARRYALPDGLFD 108
Query: 92 VE-NVIITAGAYEGTYLAF-----ESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPL 145
E +V+ +G E +L S VL+P+P + Y A LA A+PV +P
Sbjct: 109 AEKSVLPVSGTREALFLLALLAVPPSKAGRQPAVLMPNPFYAPYEGAALLAGAEPVFLPS 168
Query: 146 REENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDE 205
E F+PD D L + ++T + + P NP GA D + +A+ Y + DE
Sbjct: 169 TRETGFLPDLDALTPELLERTALFYLCTPANPQGAAADAAYLERAIGLARRYGFILAVDE 228
Query: 206 PYEHFIYDDAKHYPMLKFAP---------ENTILANSFSKTFAMTGWRLGFVVAPSEIIK 256
Y IY D L+ A N ++ +S SK + G R GFV E++
Sbjct: 229 CYAE-IYLDKPPVGALQLASGLHHGGKPWTNILVFHSLSKRSSAAGLRSGFVAGDPELMS 287
Query: 257 EMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRV 316
+L +Y + + A R E V+E R Y + L G
Sbjct: 288 RFTRLRSYSNAGMPLPVLAASAALWRDEAH---VEENRALYRAKFDAAEAALNGRYG--Y 342
Query: 317 KEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEG-------YVRISY 369
P G F+++ + D E+ + L + + V+PG + G ++RI+
Sbjct: 343 YRPDGGFFLWLEVGD----GEEATRRLWAEGGIRVLPGAYLTRCNPGEANPGAPFIRIAL 398
Query: 370 ATSREKLMEAMDRMEKAL 387
E + A + + L
Sbjct: 399 VNDAETVAHACSTIARIL 416
>dbj|BAB04151.1| (AP001508) transcriptional regulator (GntR family) [Bacillus
halodurans]
Length = 482
Score = 95.6 bits (234), Expect = 9e-19
Identities = 83/368 (22%), Positives = 155/368 (41%), Gaps = 15/368 (4%)
Query: 32 ENVISLGIGE--PDFDTPKNIKEA-CKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYDV 88
E V+ LG GE K +E +L+ Y G LREAV E+ K Y +
Sbjct: 119 EEVVRLGTGELAKGLLPVKQTEEVLASLSLEASHLSYEEAKGSLALREAVCEFVSK-YGI 177
Query: 89 DIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREE 148
+ +V+I +GA + L L ++G V + P+++ + A + V++PL +
Sbjct: 178 HVSPSSVLIVSGALQALSLMTNGLFQAGARVAVESPSYLMSLRILTSANIRGVQVPLADV 237
Query: 149 NNFMPDPDELLELVTKKTRMIVINYP--NNPTGATLDKEVAKAIADIAQDYNIYILSDEP 206
+ P L + ++ + P +NPT T V K + + Q + I+ D+
Sbjct: 238 QH---KPSVLRQYKRQQDVQMFYTIPTFHNPTNVTYSTAVRKELLHVCQAIQLPIIEDDV 294
Query: 207 YEHFIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYII 266
Y +D A P+ +L G R+G+V+ P +I + +
Sbjct: 295 YRELWFDAAPPPPLKSLDQTGNVLYLGSMSKIISPGLRVGWVIGPEPVIHRLADMKMQTD 354
Query: 267 GNVASFIQVAGVEALRSEESWKA-VKEMRKEYNERRKLVLKRLKEMPG--IRVKEPKGAF 323
+S Q L + + + + + +R + +R +L+ L+E G P G+F
Sbjct: 355 YGASSISQAIAQRWLTNNDWFTSHAQFVRDKLKNQRNAMLQLLQEHMGELAEWNRPSGSF 414
Query: 324 YVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYA-TSREKLMEAMDR 382
Y++ +K + F L K V++ PGT + Y+R+SY+ + E+L +
Sbjct: 415 YIWCKLKHPVDMNRVFHRCL--KDNVLIHPGTIYEGSKHSYIRLSYSYETGERLEYGIKA 472
Query: 383 MEKALSEL 390
+ + + E+
Sbjct: 473 LARVIHEM 480
>emb|CAA63240.1| (X92496) Aat-like protein [Azospirillum brasilense]
Length = 417
Score = 94.8 bits (232), Expect = 2e-18
Identities = 97/378 (25%), Positives = 150/378 (39%), Gaps = 36/378 (9%)
Query: 35 ISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFY---DVDID 91
I + +GEP P I E RA W Y P G + REAV + + Y D D
Sbjct: 50 IMMSVGEPQHQPPAIIDETL-RANAHLWGKYPPVGGTPEFREAVGAWLARRYALPDGLFD 108
Query: 92 VE-NVIITAGAYEGTYLAF-----ESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPL 145
E +V+ +G E +L S VL+P+P + Y A LA A+ V +P
Sbjct: 109 AEKSVLPVSGTREALFLLALLAVPPSKAGRQPAVLMPNPFYAPYEGAALLAGAESVFLPS 168
Query: 146 REENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDE 205
E F+PD D L + ++T + + P NP GA D + +A+ Y + DE
Sbjct: 169 TRETGFLPDLDALTPELLERTALFYLCTPANPQGAAADAAYLERAIGLARRYGFILAVDE 228
Query: 206 PYEHFIYDDAKHYPMLKFAP---------ENTILANSFSKTFAMTGWRLGFVVAPSEIIK 256
Y IY D L+ A N ++ +S SK + G R GFV E++
Sbjct: 229 CYAE-IYLDKPPVGALQVASGLAHDGKPWANILVFHSLSKRSSAAGLRSGFVAGDPELMS 287
Query: 257 EMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRV 316
+L +Y + + A R E V+E R Y + LK G
Sbjct: 288 RFTRLRSYSNAGMPLPVLAASAALWRDEAH---VEENRALYRAKFDAAEASLKGRYG--Y 342
Query: 317 KEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEG-------YVRISY 369
P G F+++ + D E+ + L + + V+PG + G ++RI+
Sbjct: 343 YRPDGGFFLWLEVGD----GEEATRRLWAEGGIRVLPGAYLTRCNPGEANPGAPFIRIAL 398
Query: 370 ATSREKLMEAMDRMEKAL 387
E + A + + L
Sbjct: 399 VNDAETVAHACGTIARIL 416
>pir||T36254 probable valine--pyruvate transaminase (EC 2.6.1.66) SCE68.04c
[similarity] - Streptomyces coelicolor
>gi|5123651|emb|CAB45340.1| (AL079345) putative
aminotransferase [Streptomyces coelicolor A3(2)]
Length = 404
Score = 92.4 bits (226), Expect = 8e-18
Identities = 97/399 (24%), Positives = 181/399 (45%), Gaps = 34/399 (8%)
Query: 9 IAERVILIKRSKIRELFERASKMENV-ISLGIGEPDFDTPKNIKEACKRALDEGWTH--- 64
+A R I S +R++ ++ E + + G+ P+ + I A + L E
Sbjct: 17 LAARARSIGGSPVRDILAVTARPEVINFAGGLPAPELFDAEGIAAAYRDVLAETPARALQ 76
Query: 65 YTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDP 124
Y+ G LR A+ + D +++++T G+ + L +LLE GD VL+ P
Sbjct: 77 YSTTEGEPALRAALAARTSA-RGLATDADDILVTTGSQQALSLLATALLEPGDTVLVERP 135
Query: 125 AFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYP--NNPTGATL 182
+++ ++ A A+ V +P E DP L ELV ++ ++ P +NPTG T+
Sbjct: 136 CYLAALQAFGFAGARVVAVPGDEHG---IDPGALEELVVRERPKLLYTVPTFSNPTGRTV 192
Query: 183 DKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPML---KFAPENTILANSFSKTFA 239
A+A++A ++I+ D+PY + + + P + + A + T+L SFSK A
Sbjct: 193 PAARRAAVAEVAGRCGLWIVEDDPYGELRF-EGERVPWIASYEGARDRTVLLGSFSKVMA 251
Query: 240 MTGWRLGFVVAPSE------IIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEM 293
G RLG++ AP+E + K+ LH + Q+A L + V +
Sbjct: 252 -PGLRLGWLRAPAELRRACAVAKQAADLHTPTVN------QLAAARYLADRDLDAHVARV 304
Query: 294 RKEYNERRKLVLKRLKE-MPGIRV-KEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVV 351
Y ERR +L L + +P V P+G +++ + ++ E + + V
Sbjct: 305 AAVYGERRDAMLAGLADALPAGSVWTRPEGGMFLWARLPQGYDTTALLPE--VVRHDVAY 362
Query: 352 IPGTAF--GKMGEGYVRISYAT-SREKLMEAMDRMEKAL 387
+PG F G+ +R+ + T + +++ E + R+ + L
Sbjct: 363 VPGAPFHAGEPDRATLRLCFVTQTPDEIAEGLRRLGEGL 401
>dbj|BAB04846.1| (AP001511) aminotransferase [Bacillus halodurans]
Length = 400
Score = 92.4 bits (226), Expect = 8e-18
Identities = 81/360 (22%), Positives = 166/360 (45%), Gaps = 13/360 (3%)
Query: 6 KYFIAERVILIKRSKIRELFERASKMENVISLGIGEPDFDT--PKNIKEACKRALDEGWT 63
KY A+RV + S +R++ + ++ + VIS G PD + + +++A R G
Sbjct: 2 KYAFAKRVRHLHSSAVRDILKVVNQ-QGVISFAGGLPDDELFPLEAMEDAFSRVFATGKK 60
Query: 64 --HYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLI 121
Y+ G LRE ++E + NV+IT G+ + L + GD VL
Sbjct: 61 SMQYSETEGFLPLRELILERMGRKGIRSYSERNVLITTGSQQAIDLFSRVMFNPGDVVLT 120
Query: 122 PDPAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGAT 181
DP +++ ++ + EA+ V + +E D ++ ++ K +V + +NP G
Sbjct: 121 EDPTYLAALQVFESYEAEIVPVASDDEGMIPEDLEQKMKQHKPKCVYVVPTF-SNPAGRV 179
Query: 182 LDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKF--APENTILANSFSKTFA 239
E K + ++A +++ I D+PY ++ + Y L + + ++FSKT A
Sbjct: 180 WSLERRKHLLNMAHKHHVLIFEDDPYGDIQFNQEETYVPLAAMDTGSHVLYTSTFSKT-A 238
Query: 240 MTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNE 299
+ R G++ P ++++ M + + S Q A + + ++ + + Y
Sbjct: 239 VPALRTGWITGPFQVVRMMAQAKQANDLHSNSLSQQALYQLFTHHDMDGHIQRLIEVYRS 298
Query: 300 RRKLVLKRLK--EMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAF 357
R+ +++K L+ ++PG+R EPKG +++ + + +S E + + + +PG F
Sbjct: 299 RKDVMIKTLQGADIPGLRFVEPKGGMFLWAELDEAINTSLLIKEAVAK--GMAYVPGEPF 356
>dbj|BAB05384.1| (AP001512) histidinol-phosphate aminotransferase/tyrosine and
phenylalanine aminotransferase [Bacillus halodurans]
Length = 369
Score = 92.1 bits (225), Expect = 1e-17
Identities = 76/287 (26%), Positives = 136/287 (46%), Gaps = 19/287 (6%)
Query: 17 KRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLRE 76
K K E +R +E V+ L E F + EA + AL T P+ + LR+
Sbjct: 14 KPGKPMEDVKRELGLETVVKLASNENPFGASPKVAEAIQEALHH--TAIYPDGYARTLRD 71
Query: 77 AVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLA 136
V Y V + E +I G+ E + + L ++ +P F Y +A +
Sbjct: 72 KVAHY------VGVAPEELIFGNGSDEVIQILCRAFLNEQTNTVMAEPTFSQYKLNAVIE 125
Query: 137 EAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKA-IADIAQ 195
A+ +PL++ + D D +LE++ + TR++ + PNNPTG + E ++ +A + +
Sbjct: 126 GAELREVPLKDG---VHDLDGMLEVIDENTRIVWVCNPNNPTGTYVSAEAFQSFLAKVPE 182
Query: 196 DYNIYILSDEPYEHFIYDD--AKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPSE 253
D + ++SDE Y ++ D PM++ +N ++ +FSK F + R+G+ VA
Sbjct: 183 D--VLVVSDEAYVEYVTADDYPDTVPMIR-TYKNLVVLRTFSKVFGLAALRIGYGVANQA 239
Query: 254 IIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNER 300
+I+++ + N ++F QVA V AL E ++ E E E+
Sbjct: 240 LIEKIEPVRPPF--NNSTFSQVAAVAALEDEAFVQSSVEKNNEGMEQ 284
>gb|AAC61900.1| (AF031938) hypothetical protein [Sinorhizobium meliloti]
Length = 237
Score = 91.7 bits (224), Expect = 1e-17
Identities = 58/210 (27%), Positives = 103/210 (48%), Gaps = 14/210 (6%)
Query: 20 KIREL----FERASKME--------NVISLGIGEPDFDTPKNIKEACKRALDEGWTH-YT 66
K+R L FE+ ++++ ++I LG+G PD TP++I + + + TH Y+
Sbjct: 10 KVRRLPPYVFEQVNRLKASARAAGADIIDLGMGNPDLRTPQSIVDKLCEVVQDPRTHRYS 69
Query: 67 PNAGIQQLREAVVEYYKKFYDVDIDVEN-VIITAGAYEGTYLAFESLLESGDEVLIPDPA 125
+ GI LR A YY + + V ++ E V+ T G+ EG +++ GD VL P+P
Sbjct: 70 SSKGIPGLRRAQAAYYARRFGVKLNPETQVVATLGSKEGFANMAQAITAPGDVVLCPNPT 129
Query: 126 FVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKE 185
+ + +A I + + +F P + + K +++NYP+NPT +
Sbjct: 130 YPIHAFGFLMAGGVIRSISVEPDESFFPPLERAVRHSIPKPLALILNYPSNPTAQVATLD 189
Query: 186 VAKAIADIAQDYNIYILSDEPYEHFIYDDA 215
K + A+ ++I +LSD Y +DDA
Sbjct: 190 FYKDVIAFAKKHDIIVLSDLAYSEIYFDDA 219
>pir||H83438 probable aminotransferase PA1654 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9947624|gb|AAG05043.1|AE004593_5 (AE004593) probable
aminotransferase [Pseudomonas aeruginosa]
Length = 388
Score = 90.9 bits (222), Expect = 2e-17
Identities = 97/396 (24%), Positives = 182/396 (45%), Gaps = 34/396 (8%)
Query: 10 AERVILIKRSKIRELFERASKMENVISLGIGEP-DFDTPKNIKEACKRALDEGWTHYTPN 68
+ER+ +K S IRE+ A + E V+S G P + PK E ++ + Y +
Sbjct: 4 SERISRLKSSLIREILAAAQRPE-VMSFAGGLPAEPMLPKVQWEQMPASMGQ----YGMS 58
Query: 69 AGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVS 128
G LREA+ + V + V+I +G+ + LA + ++ G EVL+ P +++
Sbjct: 59 EGEPALREAIAAEARAL-GVPCEASQVLIVSGSQQTLDLASKLFIDPGTEVLLEAPTYLA 117
Query: 129 YVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPN--NPTGATLDKEV 186
++ +L A V +PL E PD L + + + P NP+G +E
Sbjct: 118 ALQAFQLFGADCVTVPLGAEG---PDLVALRQRLERHKPAFAYLIPTFQNPSGVRYSEER 174
Query: 187 AKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPML-KFAPENTILANSFSKTFAMTGWRL 245
A+A + ++ + ++ DEPY ++D+ + P++ + + I + SKT + G R+
Sbjct: 175 RDAVAALLDEFGVTLIEDEPYRELVFDEGRATPLVSRLRKSSWIYTGTVSKTL-LPGLRV 233
Query: 246 GFVVAPSEI------IKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNE 299
GF++A ++ +K+ LH +G + +Q G EA R + E+R+ Y
Sbjct: 234 GFLIATPDLFPHLLRLKQSADLHTNRVGQWQA-LQWFGSEAYRQH-----LAELREFYRV 287
Query: 300 RRKLVLKRLKEMPG--IRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAF 357
RR + + L E G P+G + + +++ + L A V +PG F
Sbjct: 288 RRDAMQEALLEHFGELAEWNIPEGGLFFWLTLRQPLDTRTLLQPAL--AADVAFMPGEPF 345
Query: 358 GKMGE---GYVRISYA-TSREKLMEAMDRMEKALSE 389
E G +R++++ + E+L E + R+ K + +
Sbjct: 346 FAEPEQNLGRLRLNFSHVAPERLHEGLRRLAKVVRD 381
>pir||B75395 aminotransferase, class I - Deinococcus radiodurans (strain R1)
>gi|6459210|gb|AAF11020.1|AE001989_8 (AE001989)
aminotransferase, class I [Deinococcus radiodurans]
Length = 401
Score = 90.5 bits (221), Expect = 3e-17
Identities = 86/369 (23%), Positives = 160/369 (43%), Gaps = 22/369 (5%)
Query: 32 ENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYDVDID 91
E VI + I + DF I A + L G + P +L + + D+
Sbjct: 37 EGVIPMWIADMDFPVAPPILRALEDRLTRGLGY--PLGRDDRLIADLQTKWASQGLTDVP 94
Query: 92 VENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENNF 151
+ + T G Y L E GD V+ P + + + PLRE +
Sbjct: 95 ADGIHFTPSVVPGLYAGVHGLTEPGDRVVTMTPIYHPFHLAINDLGREVAAAPLREGDTR 154
Query: 152 MPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHFI 211
+ LE + R++++ +P+NP G D + + ++ +++Y++SDE +
Sbjct: 155 WEIDWDALERAAEGARLLMLCHPHNPCGRVWDADELARLRELVLAHDLYVISDELHADLR 214
Query: 212 YDDAKHYPMLKFAP-----ENTILANSFSKTFAMTGWRLGFVVA-PSEIIKEMIKLHAYI 265
+ DA P FA + T+ K F G +G +V E++ + + A +
Sbjct: 215 FTDA---PFEAFAADPRVRDRTLTVTGPCKAFNTAGLGIGVMVTHDPELLARVQRRVAGL 271
Query: 266 IGNVASFIQVAGVEALRSEESW--KAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAF 323
G+ ++ AL W + V+ +R + + +RL P +R P+ +
Sbjct: 272 GGHPSALSFTMWRVALEDGGPWLARTVEYLRGNRDFMTAFLRERL---PWVRFTVPEATY 328
Query: 324 YVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAF--GKMG---EGYVRISYATSREKLME 378
+ +++ + + E+LLE+A+V V G F G+ G +G++R+++ATSR L E
Sbjct: 329 LAWLDLRE-HPEAGRIQEFLLEEAKVAVHNGPTFAPGEQGAAYQGFIRVNFATSRAILTE 387
Query: 379 AMDRMEKAL 387
A++RM +AL
Sbjct: 388 ALERMARAL 396
>pir||B69780 transcription regulator GntR family homolog ydfD - Bacillus
subtilis >gi|1881344|dbj|BAA19371.1| (AB001488) SIMILAR
TO THE RHIZOPINE CATABOLISM (MOCR) GENE OF RHIZOBIUM
MELILOTI. [Bacillus subtilis]
>gi|2632837|emb|CAB12344.1| (Z99106) similar to
transcriptional regulator (GntR family) /
aminotransferase (MocR-like) [Bacillus subtilis]
Length = 482
Score = 89.7 bits (219), Expect = 5e-17
Identities = 83/338 (24%), Positives = 155/338 (45%), Gaps = 25/338 (7%)
Query: 65 YTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDP 124
Y G LREA+ Y K +++ +++I +GA + L LL+ G V + P
Sbjct: 155 YEEPKGYLPLREALSNYLKTI-GINVSSSSILIVSGALQALQLISMGLLQRGSTVYLDQP 213
Query: 125 AFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYP--NNPTGATL 182
+++ + + A K +P+ E +P+ L ++ R I+ P +NPTG +
Sbjct: 214 SYLYSLHVFQSAGMKLTGLPMDNE-GLLPENVHLTR--GERGRAILYTNPCFHNPTGILM 270
Query: 183 DKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTIL-ANSFSKTFAMT 241
K+ + I ++++ + I+ D+ Y D+ YP+ +L S SKT +
Sbjct: 271 SKKRREEILAVSENTQLPIIEDDIYRELWIDEIPPYPIKTIDKNGHVLYIGSLSKTLS-P 329
Query: 242 GWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERR 301
G R+G++V P +I+ + + +S Q E S + V+++R++ RR
Sbjct: 330 GLRIGWIVGPEPVIERLSDIKMQTDYGSSSLSQRVAAEWFTSGHYQQHVEKVRQQLKVRR 389
Query: 302 KLVLK----RLKEMPGIRVKEPKGAFYVF----PSIKDTGMSSEKFSEWLLEKARVVVIP 353
+L L LKE+ + PKG F+V+ PSI + ++ S+ +L +
Sbjct: 390 ELALSALETHLKEVATWNI--PKGGFFVWIKILPSISMKLLYTKALSKGIL------INL 441
Query: 354 GTAFGKMGEGYVRISYA-TSREKLMEAMDRMEKALSEL 390
G+ + + Y+R+SYA S E L + + + + EL
Sbjct: 442 GSIYAQEKGNYIRLSYAYASLEDLQKGIYELGLMIKEL 479
>pir||T14609 alanine transaminase homolog - Trypanosoma cruzi
>gi|3063546|gb|AAC14082.1| (AF052832) unknown
[Trypanosoma cruzi]
Length = 497
Score = 89.7 bits (219), Expect = 5e-17
Identities = 93/374 (24%), Positives = 167/374 (43%), Gaps = 56/374 (14%)
Query: 65 YTPNAGIQQLREAVV-EYYKKFYDVD--IDVENVIITAGAYEGTYLAFESLL-ESGDEVL 120
YT +AG +R+ V + ++ +++ +D ++ +T GA G L + L+ ++ D V+
Sbjct: 117 YTDSAGYAFVRDIVARQINERDHEIKPLVDASSIFLTDGASSGVRLLLQVLVGDASDAVM 176
Query: 121 IPDPAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELL----ELVTKKT---RMIVINY 173
+P P + Y L P L E++N+ + +EL E V K R++V+
Sbjct: 177 VPIPQYPLYTAQLTLLGGTPAMYYLCEKDNWALNVEELASVYDECVAKNNATPRVLVVIN 236
Query: 174 PNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKF--------AP 225
P NPTG LD++V +A+A D I +++DE Y+ +Y K + L F AP
Sbjct: 237 PGNPTGGVLDRDVMEAVAKFCCDRGIVLMADEVYQENVYAAGKRF--LSFREVVLGLPAP 294
Query: 226 EN--TILANSFSKT---FAMTGWRLGFVVA---PSEIIKEMIKLHAYI-IGNVASFIQVA 276
N T+LA+ S + G R G+ P+ + ++++K+ + + +V + A
Sbjct: 295 YNTDTVLASLHSTSKGIIGECGRRGGYFCLTNFPAPVREQVLKMCSMVPCSSVNGQLMTA 354
Query: 277 GVEA------LRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIK 330
+ + E W + +R L+ K L + G + +GA Y FP+I+
Sbjct: 355 LMCSPPRPGDASYESYWAEYNGIFASLKKRALLLAKELSTIRGFSCQPVEGAMYAFPTIE 414
Query: 331 --------------DTGMSSEKFSEW---LLEKARVVVIPGTAFGKMGEGYVRISYATSR 373
G + W LLE + VVV+ G+ FG+ + + T+
Sbjct: 415 LPEKYFQHNEELNAKEGRKLGPDTRWALELLESSGVVVVAGSGFGQQPN---TLHFRTTI 471
Query: 374 EKLMEAMDRMEKAL 387
+ M+RM KA+
Sbjct: 472 LPPEQQMERMVKAM 485
>gb|AAF50113.1| (AE003546) CG6321 gene product [Drosophila melanogaster]
Length = 418
Score = 88.9 bits (217), Expect = 9e-17
Identities = 90/408 (22%), Positives = 180/408 (44%), Gaps = 41/408 (10%)
Query: 20 KIRELFERAS---KMENVISLGIGEP-------DFDTPKNIKEAC----KRALDEGWTHY 65
K++ LF+ N+++LG+G P + D+ + + C KR Y
Sbjct: 9 KLKHLFDGGDWNVYAPNILNLGVGAPGPDILTANCDSFRTATDHCLEREKRENQSLIFQY 68
Query: 66 TPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPA 125
P +G ++R + Y+ + + ++ E++IIT GA G ++ ++L+ V + +
Sbjct: 69 GPTSGTFEVRREISTYFTEMFKSPVNCEDLIITTGASHGLHILLSTMLDFEGFVFVDEYT 128
Query: 126 FVSYVEDAK-LAEAKPVRIPLREENNFMPDPDELL---ELVTKKTRMIVINYP----NNP 177
++ ++ K + V + L ++ + D +E + +KK I Y +NP
Sbjct: 129 YMIALDSIKHFSTVTIVPVKLNDDGVDLKDLEEKVSKRRFQSKKKEFWGIYYTIPTYHNP 188
Query: 178 TGATLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDA-KHYPMLKFAPEN-------TI 229
TG EV + I +A++Y+ ++ D+ Y Y + H +L + N I
Sbjct: 189 TGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYGETPTHSRLLSYDDRNDANFAGHVI 248
Query: 230 LANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGV--EALRSEESW 287
SFSK G RLG++ P +K ++ + +G+ + +
Sbjct: 249 SNGSFSKILG-PGVRLGWLEVPPR-LKPILDGSGFATSGGCFNNYTSGIVGSLFELKLAQ 306
Query: 288 KAVKEMRKEYNERRKLVLKRLK-EMPG-IRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLE 345
K + E + Y ER + L+ E+P ++ P G ++++ I D + +F ++ +E
Sbjct: 307 KQISESYEAYKERMLATTQVLRDELPDCCKLVSPTGGYFIWVRIPDR-LDCREFLKYCME 365
Query: 346 KARVVVIPGTAF---GKMGEGYVRISYA-TSREKLMEAMDRMEKALSE 389
++ I GT F G+ G+ + R+S A + KL++ R+ AL +
Sbjct: 366 NHKIYFIVGTRFSADGQSGKQFFRLSIAFYPKSKLVDGARRLCNALKD 413
>gi|6754408 kynurenine aminotransferase II [Mus musculus]
>gi|5106393|gb|AAD39680.1|AF072376_1 (AF072376)
kynurenine aminotransferase II [Mus musculus]
Length = 425
Score = 88.5 bits (216), Expect = 1e-16
Identities = 87/365 (23%), Positives = 169/365 (45%), Gaps = 40/365 (10%)
Query: 55 KRALDEGWTHYTPNAGIQQLREAVVEYYKKF-------YDVDIDVENVIITAGAYEGTYL 107
KRAL Y+P+ GI +L + ++ K Y + ++ IT+G +G
Sbjct: 69 KRALQ-----YSPSYGIPELLSWLKQFQVKLHNPPTVNYPPNQGQMDLCITSGCQDGLCK 123
Query: 108 AFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENNFMPD----------PDE 157
AFE L+ GD +L+ +P F + K + +P +E+ +P+ P++
Sbjct: 124 AFEMLINPGDTILVNEPLFPGTLYAMKPLGCNIINVP-SDEHGIIPEGLKKILSQWKPED 182
Query: 158 LLELVTKKTRMIVINYPN--NPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDA 215
+ TKKT + PN NPTG +L + K I ++A+ Y+ I+ D+PY +
Sbjct: 183 SKD-PTKKTPKFLYTVPNGNNPTGNSLTGDRKKEIYELARKYDFLIIEDDPYYFLQFSKP 241
Query: 216 KHYPMLKFAPENTIL-ANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIG-NVASFI 273
L + ++ A++FSKT + +G R+GF+ P +I+ ++ LH + + +
Sbjct: 242 WEPTFLSMDVDGRVIRADTFSKTVS-SGLRVGFMTGPKTLIQNIV-LHTQVSSVHACTLS 299
Query: 274 QVAGVEALR--SEESWKAVKEMRKEY--NERRKLVLKRLKEMPGI-RVKEPKGAFYVFPS 328
Q+ ++ L EE + A + ++ N+R ++ K + G+ PK +++
Sbjct: 300 QLMILQLLHQWGEEGFLAHIDRTIDFYKNQRDSILAAADKWLRGLAEWHVPKAGMFLWIK 359
Query: 329 IKDTGMSSEKFSEWLLEKARVVVIPGTAF---GKMGEGYVRISYATSREKLME-AMDRME 384
+K + + E +E+ V+++PG F G + R S++ + M+ A R+
Sbjct: 360 VKGISDTKQLIEEKAIER-EVLLVPGNGFFIDGSAPTSFFRASFSLATPAQMDTAFQRLA 418
Query: 385 KALSE 389
+ + E
Sbjct: 419 QLIKE 423
>gb|AAK43337.1| Aspartate aminotransferase (aspB-4) [Sulfolobus solfataricus]
Length = 380
Score = 87.0 bits (212), Expect = 3e-16
Identities = 87/371 (23%), Positives = 169/371 (45%), Gaps = 19/371 (5%)
Query: 28 ASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTH--YTPNAGIQQLREAVVEYYKKF 85
A +++ ++ G +P K IK+A L+E + P AG Q+ E + E KF
Sbjct: 21 AKRVKINMASGTPDPRKMPIKEIKDAYSEVLNELGPKVLFYPGAGGQE--ELIREIEDKF 78
Query: 86 YDV----DIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPV 141
V E +++T+GA L + LE+ D + + +P F+ KL + +
Sbjct: 79 LSVLNLTKRKDEKIVVTSGAQHAMELLGKYFLEN-DVIAVENPTFIETFNALKLRSSSVI 137
Query: 142 RIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYI 201
I L + + + LL++V + ++ N +NP G + + K + ++A+ Y+ YI
Sbjct: 138 PISLDPSGIDVNELETLLKVVKIRLLYVIPNC-HNPAGVNMSECRRKRLIELAEKYDFYI 196
Query: 202 LSDEPYEHFIYDDAKHYPMLKFAPENTIL-ANSFSKTFAMTGWRLGFVVAPSEIIKEMIK 260
+ D+PY + + P+ + ++ +SFSK A G R+GF++A E I E I
Sbjct: 197 IEDDPYRPIAGETPQ--PIKNYDNNGRVIYVSSFSKIIA-PGLRVGFLIA-KEDIAEKIS 252
Query: 261 LHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPK 320
L + + ++ Q LR + KE+ + Y + K+++ L + + EPK
Sbjct: 253 LMEQLDFSTSTINQYVVARLLRKGVVTERSKELYEHYKSKMKILVDSLVDKGLDKFNEPK 312
Query: 321 GAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYA-TSREKLMEA 379
F++ + D G S +EK V F + G+ R+S + ++E+++E
Sbjct: 313 CGFFL---LLDVGKDSWNVFHKAVEKGLSFVPAKPFFLRGGDTMARLSVSVATKEEIIEG 369
Query: 380 MDRMEKALSEL 390
+ + + + +
Sbjct: 370 VKILNEVIRNI 380
>emb|CAA08874.1| (AJ009834) DapC [Bordetella pertussis]
Length = 397
Score = 86.6 bits (211), Expect = 4e-16
Identities = 87/387 (22%), Positives = 172/387 (43%), Gaps = 35/387 (9%)
Query: 20 KIRELFERASKMEN---VISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLRE 76
K+R L A K + I+L IGEP P + +A L G + Y G LR+
Sbjct: 15 KLRALLADAGKPTHDLPPINLSIGEPKHAAPACVGQAIAANL-AGLSVYPSTKGEPALRQ 73
Query: 77 AVVEYYKKFYDVDI-DVENVIITA-GAYEGTYLAFESLLE--SGDEVLIPDPAFVSYVED 132
A+ ++ + Y + D E+ ++ G+ E + +++++ +G V+ P+P + Y
Sbjct: 74 AISQWLSRRYSIPAPDPESEVLPVLGSREALFAFAQTVIDPSAGALVVCPNPFYQIYEGA 133
Query: 133 AKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIAD 192
A LA A P + +F + + V ++T+++ + P NP G + E + + +
Sbjct: 134 ALLAGATPYYVNADPARDFGLRTGRVPDEVWRRTQLVFVCSPGNPAGNVMSLEEWRTLFE 193
Query: 193 IAQDYNIYILSDEPY-EHFIYDDAKHYPMLKFAPE-------NTILANSFSKTFAMTGWR 244
++ + I + E Y E ++ +D L+ A N + +S SK + G R
Sbjct: 194 LSDRHGFVIAAYECYSEIYLDEDTPPLGSLQAARRLGRDRYTNLVAFSSLSKRSNVPGMR 253
Query: 245 LGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRK--EYNERRK 302
GFV + ++ + Y ++ + A + A W + RK +Y + +
Sbjct: 254 SGFVAGDAALLARFLLYRTYHGSAMSPVVSAASIAA------WSMRRMCRKTAQYRAKFE 307
Query: 303 LVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGK--- 359
VL L+ + + V+ P+ +FY++ T S F+ L + V V+PG+ +
Sbjct: 308 AVLPILQNV--LDVRAPQASFYLWAG---TPGSDTAFARELYGRTGVTVLPGSLLAREAH 362
Query: 360 ---MGEGYVRISYATSREKLMEAMDRM 383
G+G +RI+ ++ ++A +R+
Sbjct: 363 NANPGQGRIRIALVAPLDQCVQAAERI 389
>sp|Q10334|ALAT_SCHPO PUTATIVE ALANINE AMINOTRANSFERASE (GLUTAMIC--PYRUVIC TRANSAMINASE)
(GPT) (GLUTAMIC--ALANINE TRANSAMINASE)
>gi|7490106|pir||T37975 probable alanine
aminotransferase - fission yeast (Schizosaccharomyces
pombe) >gi|7492366|pir||T40567 probable alanine
aminotransferase - fission yeast (Schizosaccharomyces
pombe) >gi|1216244|emb|CAA93786.1| (Z69909)
aminotransferase [Schizosaccharomyces pombe]
>gi|5420444|emb|CAB46671.1| (AL096788) putative alanine
aminotransferase [Schizosaccharomyces pombe]
Length = 505
Score = 85.4 bits (208), Expect = 1e-15
Identities = 97/388 (25%), Positives = 168/388 (43%), Gaps = 47/388 (12%)
Query: 47 PKNIKEACKRALDEGWT--HYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEG 104
P ++ + K L E + Y+ + GI +R V ++ + D + ++ +T+GA
Sbjct: 116 PTDVVQRSKMLLKESGSLGAYSASQGIPLVRRHVADFIRARDGFDCEPSDIYLTSGASHA 175
Query: 105 TYLAFESLL-ESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDEL---LE 160
L ++ D V++P P + Y L V L EENN+ D D+ +
Sbjct: 176 ARLIMTLIIARPTDGVMVPAPQYPLYGAQIDLMSGSMVSYSLSEENNWDIDFDQFKKSFD 235
Query: 161 LVTKK---TRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKH 217
+KK R+ V+ P NPTGA + + + + A+ I +L+DE Y++ IY + H
Sbjct: 236 EASKKGINVRLCVVINPGNPTGACISENSMEKVLRFAKAKGIVLLADEVYQNNIYQNKFH 295
Query: 218 YPMLKFA------PEN------TILANSFSK-TFAMTGWRLGF---VVAPSEIIKEMIKL 261
K P+N I NS SK F G R G+ V P +++KL
Sbjct: 296 SFRRKLGELREKEPDNHWDQVSLISVNSVSKGQFGECGQRGGYLDVVNIPEPAKDQILKL 355
Query: 262 HAY-IIGNVAS--FIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRL----KEMPGI 314
I VA + + + S+ + E +E +L ++L K M +
Sbjct: 356 ATIDICPPVAGQLLVDMLVNPPKPGDPSYDLFIKEVDEIHEALRLQCRQLYEGTKRMKRV 415
Query: 315 RVKEPKGAFYVFPSIK-----------DTGMSSEKFSEWLLEKARVVVIPGTAFGK-MGE 362
EP GA Y+ PS+ E ++ LL+++ + V+PG+ FG+ G+
Sbjct: 416 SCLEPHGAMYLHPSVSLPEKLITTAKAQKIQPDEFYAIELLKRSGICVVPGSGFGQPEGD 475
Query: 363 GYVRISYATSREKLMEAMDRMEKALSEL 390
++RI++ K E ++R KA +E+
Sbjct: 476 YHIRITFLA---KGTEYIERFVKAHNEI 500
>emb|CAC14933.1| (AL449216) putative transferase [Streptomyces coelicolor]
Length = 393
Score = 84.7 bits (206), Expect = 2e-15
Identities = 89/366 (24%), Positives = 159/366 (43%), Gaps = 21/366 (5%)
Query: 33 NVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYDVD-ID 91
+V+ L + E D + + A A++ G T Y EA+ + K + D +
Sbjct: 37 DVLPLWVAEMDVPLARPVVRAVTEAMELGDTGYPVGTAYA---EALAAFAAKRWGWDGLA 93
Query: 92 VENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENNF 151
VE I G + + GD V++ P + + + + + V PL +
Sbjct: 94 VERTAIVPDVMLGVVEMLKLVTGPGDPVIVNPPVYPPFYQFVTHMDRRVVEAPLGPDLRI 153
Query: 152 MPDPDELLELVTKKT------RMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDE 205
+LE V ++ ++ P+NPTG E A+A +A+ Y + +++DE
Sbjct: 154 DLG---VLEAVFRRAVAGGGRAAFLLCSPHNPTGTVHTAEELAAVAALAERYGVRVVADE 210
Query: 206 PYEHFIY-DDAKHYPMLKF-APENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHA 263
+ + DA+ P L E + S SK + + G + VA ++ ++
Sbjct: 211 IHAPVVTAPDARFVPYLGVPGAERGLSLMSASKGWNLAGLKAALAVAGPGAAADLARMPE 270
Query: 264 YIIGNVASFIQV-AGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKE-MPGIRVKEPKG 321
+ G+ S I V A ALR +W + + +E R+L+ L E +PG+ + +
Sbjct: 271 EV-GHGPSHIGVLAHTAALRDGTAW--LDAVLAGLDENRRLLTGLLAERLPGVVHRAGEA 327
Query: 322 AFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAMD 381
+ + + G+ E ++ L++ RV + G FG G G+VR++ ATS E L EA+
Sbjct: 328 TYLAWLDCRALGLGDEP-ADVFLDRGRVALSSGVPFGSGGPGHVRLNLATSPEVLTEAVR 386
Query: 382 RMEKAL 387
RM AL
Sbjct: 387 RMAAAL 392
>sp|Q00379|1A12_CUCPE 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE 2 (ACC SYNTHASE)
(S-ADENOSYL-L-METHIONINE METHYLTHIOADENOSINE-LYASE)
>gi|99627|pir||B41141 1-aminocyclopropane-1-carboxylate
synthase (EC 4.4.1.14) 1B - zucchini
Length = 494
Score = 80.4 bits (195), Expect = 3e-14
Identities = 75/346 (21%), Positives = 153/346 (43%), Gaps = 29/346 (8%)
Query: 70 GIQQLREAVVEYYKKFYD--VDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
G+Q+ R+A+ + K V D +++ GA + L + GD L+P P +
Sbjct: 97 GLQEFRKAMASFMGKVRGGRVKFDPSRIVMGGGATGASETVIFCLADPGDAFLVPSPYYA 156
Query: 128 SYVEDAKL-AEAKPVRIPLREENNFMPDPDELLELVTKKTRM-------IVINYPNNPTG 179
++ D K A+ + + NNF + LE+ KK + ++I P+NP G
Sbjct: 157 AFDRDLKWRTRAQIIPVHCNSSNNFQVT-EAALEIAYKKAQEANMKVKGVIITNPSNPLG 215
Query: 180 ATLDKEVAKAIADIAQDYNIYILSDEPYEHFIY------DDAKHYPMLKFAPENTI-LAN 232
T D++ K + ++I+++ DE Y ++ A+ ++ + I +
Sbjct: 216 TTYDRDTLKTLVTFVNQHDIHLICDEIYSATVFKAPTFTSIAEIVEQMEHCKKELIHILY 275
Query: 233 SFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESW--KAV 290
S SK + G+R+G + + ++++ + G V+S Q + A+ S+E + K +
Sbjct: 276 SLSKDMGLPGFRVGIIYSYNDVVVRRAR-QMSSFGLVSSQTQHL-LAAMLSDEDFVDKFL 333
Query: 291 KEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPS----IKDTGMSSE-KFSEWLLE 345
E K ER K L +M GI +V+ +KD +E + ++
Sbjct: 334 AENSKRLGERHARFTKELDKM-GITCLNSNAGVFVWMDLRRLLKDQTFKAEMELWRVIIN 392
Query: 346 KARVVVIPGTAFGKMGEGYVRISYATSREKLME-AMDRMEKALSEL 390
+ ++ V PG++F G+ R+ +A + ++ A++R+ + +
Sbjct: 393 EVKLNVSPGSSFHVTEPGWFRVCFANMDDNTVDVALNRIHSFVENI 438
>gb|AAF42764.1|AF128839_8 (AF128839) unknown [Salmonella enteritidis]
Length = 475
Score = 80.4 bits (195), Expect = 3e-14
Identities = 81/355 (22%), Positives = 160/355 (44%), Gaps = 25/355 (7%)
Query: 21 IRELFERASKMENVISLGIGEPD---FDTP---KNIKEACKRALDEGWTHYTPNAGIQQL 74
I E+ + AS+ +V+ PD F P +++ + K A P G +L
Sbjct: 93 IFEMLQLASRDTSVVPFASAFPDPRLFPLPQLNRSLAQVSKTATAMSVIENLP-PGNAEL 151
Query: 75 REAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAK 134
R A+ Y + + + ++ITAGA E L+ +++ GD V++ +P F ++ +
Sbjct: 152 RYAIARRYA-LQGITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALE 210
Query: 135 LAEAKPVRIP--LREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIAD 192
K + IP ++E + M L E K ++ + NP G TL E +
Sbjct: 211 RLRLKALSIPTDVKEGIDLMALEQALQEYPVKACWLMTNS--QNPLGFTLSAEKKARLVA 268
Query: 193 IAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTIL-ANSFSKTFAMTGWRLGFVVAP 251
+ +N+ ++ D+ Y + K P + ++T+L +SFSK + G+R+G+V
Sbjct: 269 LLTHHNVTLIEDDVYSELYFGREKPLPAKAWDRDDTVLHCSSFSKCL-VPGFRIGWVAGG 327
Query: 252 SEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKR-LKE 310
S +++ +L + +S +Q+A V+ L + ++ +R++ ER++ + L+
Sbjct: 328 SH-ARQIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQQAWQTLLRH 386
Query: 311 MPG-IRVKEPKGAFYVF---PSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMG 361
+P +++ ++++ P D G S K E L+ + PG F G
Sbjct: 387 LPAEVKIHHNDSGYFLWLELPEQLDAGELSAKALEHLIS-----IAPGKMFSTSG 436
>dbj|BAA94600.1| (AB033503) 1-aminocyclopropane-1-carboxylate synthase [Populus
euramericana]
Length = 486
Score = 80.4 bits (195), Expect = 3e-14
Identities = 80/347 (23%), Positives = 157/347 (45%), Gaps = 33/347 (9%)
Query: 70 GIQQLREAVVEYYKKFYD--VDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
G+ + R+A+ ++ + V D + ++++ GA L L + GD L+P P +
Sbjct: 91 GLPEFRQAIAKFMGRVRGGRVTFDPDRIVMSGGATGANELIMFCLADPGDAFLVPSPYYP 150
Query: 128 SYVEDAKLAEA-KPVRIPLREENNFMPDPDELLELVTK------KTRMIVINYPNNPTGA 180
++ D + V + NNF L K + ++I P+NP G
Sbjct: 151 AFYRDLGWRTGVQIVPVDCDSSNNFQITKVALEAAYDKAQQDGINVKGLIITNPSNPLGT 210
Query: 181 TLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILAN-------- 232
TLD+E K + + NI+I+ DE Y I+ ++++ + E + N
Sbjct: 211 TLDRETLKCLLSFINEKNIHIVCDEIYAATIF-SSQNFVSVSEVIEEVMDCNRDLIHIVY 269
Query: 233 SFSKTFAMTGWRLGFVVAPSE-IIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWK-AV 290
S SK + G+R+G V + ++ ++ K+ ++ G V+S Q L EE + +
Sbjct: 270 SLSKDMGLPGFRVGIVYSYNDAVVNCGRKMSSF--GLVSSQTQYLLASMLSDEEFVEDFL 327
Query: 291 KEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVV 350
E K +R + K L+++ GI E K +V+ +++ + E+ ++ +E RV+
Sbjct: 328 AESSKRLKKRHGIFTKGLEQI-GISCLESKAGLFVWMNLRH--LLKEQTNDGEMELWRVI 384
Query: 351 -------VIPGTAFGKMGEGYVRISYATSREKLME-AMDRMEKALSE 389
V PG++F + G+ R+ +A ++ +E A+ R+ + E
Sbjct: 385 VNDVKLNVSPGSSFHCVEPGWFRVCFANMDDETLEVALKRIHAFVGE 431
>pir||A41141 1-aminocyclopropane-1-carboxylate synthase (EC 4.4.1.14) 1A -
zucchini >gi|167494|gb|AAA33111.1| (M61195)
1-aminocyclopropane-1-carboxylate synthase [Cucurbita
pepo]
Length = 493
Score = 79.6 bits (193), Expect = 6e-14
Identities = 75/346 (21%), Positives = 150/346 (42%), Gaps = 29/346 (8%)
Query: 70 GIQQLREAVVEYYKKFYD--VDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
G+ + R A+ + K V D +++ GA + L + GD L+P P +
Sbjct: 97 GLPEFRNAIANFMGKVRGGRVKFDPSRIVMGGGATGASETVIFCLADPGDAFLVPSPYYA 156
Query: 128 SYVEDAKL-AEAKPVRIPLREENNFMPDPDELLELVTKKTRM-------IVINYPNNPTG 179
+ D K A+ +R+ NNF LE+ KK + ++I P+NP G
Sbjct: 157 GFDRDLKWRTRAQIIRVHCNRSNNFQVTK-AALEIAYKKAQEANMKVKGVIITNPSNPLG 215
Query: 180 ATLDKEVAKAIADIAQDYNIYILSDEPYEHFIY------DDAKHYPMLKFAPENTI-LAN 232
T D++ K + ++I+++ DE Y ++ A+ ++ + I +
Sbjct: 216 TTYDRDTLKTLVTFVNQHDIHLICDEIYSATVFKAPTFTSIAEIVEQMEHCKKELIHILY 275
Query: 233 SFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESW--KAV 290
S SK + G+R+G + + ++++ + G V+S Q + A+ S+E + K +
Sbjct: 276 SLSKDMGLPGFRVGIIYSYNDVVVRRAR-QMSSFGLVSSQTQHL-LAAMLSDEDFVDKFL 333
Query: 291 KEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPS----IKDTGMSSE-KFSEWLLE 345
E K ER K L +M GI +V+ +KD +E + ++
Sbjct: 334 AENSKRVGERHARFTKELDKM-GITCLNSNAGVFVWMDLRRLLKDQTFKAEMELWRVIIN 392
Query: 346 KARVVVIPGTAFGKMGEGYVRISYATSREKLME-AMDRMEKALSEL 390
+ ++ V PG++F G+ R+ +A + ++ A++R+ + +
Sbjct: 393 EVKLNVSPGSSFHVTEPGWFRVCFANMDDNTVDVALNRIHSFVENI 438
>pir||E70478 histidinol-phosphate aminotransferase - Aquifex aeolicus
>gi|2984289|gb|AAC07813.1| (AE000771)
histidinol-phosphate aminotransferase [Aquifex aeolicus]
Length = 354
Score = 79.2 bits (192), Expect = 7e-14
Identities = 89/367 (24%), Positives = 163/367 (44%), Gaps = 49/367 (13%)
Query: 35 ISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYDVDIDVEN 94
+ L E +D P+ IK+ L + + P+ ++L+ + +++ + EN
Sbjct: 21 VRLSSNEFPYDFPEEIKQRALEELKKVPLNKYPDPEAKELKAVLADFF------GVKEEN 74
Query: 95 VIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENNFMPD 154
+++ G+ E Y ++ E V IP P F Y AK+ V++ L E NF D
Sbjct: 75 LVLGNGSDELIYYLSIAIGELYIPVYIPVPTFPMYEISAKVLGRPLVKVQLDE--NFDID 132
Query: 155 PDELLELVTKKTRMI-VINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEH---- 209
+ +EL+ K+ ++ YPNNPTG + + I ++ ++ + DE Y H
Sbjct: 133 LERSIELIEKEKPVLGYFAYPNNPTGNLFSRGKIEEI----RNRGVFCVIDEAYYHYSGE 188
Query: 210 -FIYDDAKHYPMLKFAPENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLH-----A 263
F+ D K E+T++ + SK M R+G ++ EI+ E+ K+
Sbjct: 189 TFLEDALKR--------EDTVVLRTLSK-IGMASLRVGILIGKGEIVSEINKVRLPFNVT 239
Query: 264 YIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAF 323
Y +A + G E L E+ + VKE + Y+E +K++ G+ V K F
Sbjct: 240 YPSQVMAKVLLTEGREFL-MEKIQEVVKERERMYDE--------MKKIEGVEVFPSKANF 290
Query: 324 YVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSRE--KLMEAMD 381
+F + + E + E L R V++ ++ + + +R+S E K +EA++
Sbjct: 291 LLF---RTPYPAHEVYQELL---KRDVLVRNVSYMEGLQKCLRVSVGKPEENNKFLEALE 344
Query: 382 RMEKALS 388
K+LS
Sbjct: 345 ESIKSLS 351
>sp|P23279|1A11_CUCPE 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE 1 (ACC SYNTHASE)
(S-ADENOSYL-L-METHIONINE METHYLTHIOADENOSINE-LYASE)
>gi|99625|pir||A38649 1-aminocyclopropane-1-carboxylate
synthase (EC 4.4.1.14) - zucchini
>gi|167497|gb|AAA33113.1| (M58323)
1-aminocyclopropane-1-carboxylate synthase [Cucurbita
pepo]
Length = 493
Score = 78.8 bits (191), Expect = 1e-13
Identities = 75/346 (21%), Positives = 150/346 (42%), Gaps = 29/346 (8%)
Query: 70 GIQQLREAVVEYYKKFYD--VDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
G+ + R A+ + K V D +++ GA + L + GD L+P P +
Sbjct: 97 GLPEFRNAIANFMGKVRGGRVKFDPSRIVMGGGATGASETVIFCLADPGDAFLVPSPYYA 156
Query: 128 SYVEDAKL-AEAKPVRIPLREENNFMPDPDELLELVTKKTRM-------IVINYPNNPTG 179
+ D K A+ +R+ NNF LE+ KK + ++I P+NP G
Sbjct: 157 GFDRDLKWRTRAQIIRVHCNGSNNFQVTK-AALEIAYKKAQEANMKVKGVIITNPSNPLG 215
Query: 180 ATLDKEVAKAIADIAQDYNIYILSDEPYEHFIY------DDAKHYPMLKFAPENTI-LAN 232
T D++ K + ++I+++ DE Y ++ A+ ++ + I +
Sbjct: 216 TTYDRDTLKTLVTFVNQHDIHLICDEIYSATVFKAPTFTSIAEIVEQMEHCKKELIHILY 275
Query: 233 SFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESW--KAV 290
S SK + G+R+G + + ++++ + G V+S Q + A+ S+E + K +
Sbjct: 276 SLSKDMGLPGFRVGIIYSYNDVVVRRAR-QMSSFGLVSSQTQHL-LAAMLSDEDFVDKFL 333
Query: 291 KEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPS----IKDTGMSSE-KFSEWLLE 345
E K ER K L +M GI +V+ +KD +E + ++
Sbjct: 334 AENSKRVGERHARFTKELDKM-GITCLNSNAGVFVWMDLRRLLKDQTFKAEMELWRVIIN 392
Query: 346 KARVVVIPGTAFGKMGEGYVRISYATSREKLME-AMDRMEKALSEL 390
+ ++ V PG++F G+ R+ +A + ++ A++R+ + +
Sbjct: 393 EVKLNVSPGSSFHVTEPGWFRVCFANMDDNTVDVALNRIHSFVENI 438
>emb|CAB61674.1| (AL133213) putative GntR-family regulatory protein. [Streptomyces
coelicolor A3(2)]
Length = 500
Score = 78.8 bits (191), Expect = 1e-13
Identities = 92/369 (24%), Positives = 157/369 (41%), Gaps = 24/369 (6%)
Query: 33 NVISLGIGEPDFDTPKNIKEACKRALDE----GWTHYTPNAGIQQLREAVVEYYKKFYDV 88
+VI LG P + A + AL+E TH AG+ LR + E Y +
Sbjct: 120 SVIDLGCAALPAPEPW-LTRAVQGALEELPPYAHTHGDYPAGLPALRAMIAERYTA-RGI 177
Query: 89 DIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREE 148
E +++T GA G+ + + P++ + ++ + A A+ V + + E
Sbjct: 178 PTMPEQIMVTTGAMGAIDAICHLFGGRGERIAVESPSYANILQLMREAGARLVPVAMAEG 237
Query: 149 NNFMPDPD---ELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDE 205
D D ++L + +V ++ +NPTGA D + + + D A+ +++DE
Sbjct: 238 LTGW-DVDRWRQVLRDAAPRIAYVVADF-HNPTGALADDDQRRRLVDAARSAGTVLVADE 295
Query: 206 PYEHFIYDDAKHY--PMLKFAP--ENTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKL 261
D+ P+ F P I S SK F G R+G+V A ++I+ ++
Sbjct: 296 TMSELWLDEDVEMPRPVCAFDPAGSTVITVGSASKAF-WAGMRIGWVRAAPDVIRSLVAA 354
Query: 262 HAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEY--NERRKLVLKRLKEMPGIRVKEP 319
AY Q+A V L S W+ +R+E R +LV +E+P + P
Sbjct: 355 RAYADLGTPVLEQLA-VNWLFSTGGWEQAVTVRREQARQNRDELVAAVRRELPDWEFEVP 413
Query: 320 KGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMG--EGYVRISYATSREKLM 377
+G ++ ++ G+S + +E E+ V V G FG G EGYVR+ +
Sbjct: 414 RGGLTLW--VRTGGLSGSRLAE-AGERVGVRVPSGPRFGVDGAFEGYVRLPFTVGGAVAE 470
Query: 378 EAMDRMEKA 386
EA R+ A
Sbjct: 471 EAAVRLAAA 479
>gb|AAC83146.1| (AF057562) 1-aminocyclopropane-1-carboxylate synthase [Nicotiana
glutinosa]
Length = 489
Score = 78.4 bits (190), Expect = 1e-13
Identities = 72/344 (20%), Positives = 150/344 (42%), Gaps = 28/344 (8%)
Query: 70 GIQQLREAVVEYYKKFYD--VDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
G+ + R A+ ++ +K V D E V++ GA L ++GD L+P P +
Sbjct: 95 GLTEFRRAIAKFMEKTRGGRVTFDPERVVMAGGATGANETIIFCLADAGDAFLVPSPYYP 154
Query: 128 SYVEDAKLAEA-KPVRIPLREENNFMPDPDELLELVTK------KTRMIVINYPNNPTGA 180
++ D + + + IP NNF + E+ K + +++ P+NP G
Sbjct: 155 AFNRDLRWRTGVQLIPIPCDSSNNFQITTKAVKEVYENAQKSNIKVKGLILTNPSNPLGT 214
Query: 181 TLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILAN-------- 232
TLD++ K + +NI+++ DE Y ++ + + + + N
Sbjct: 215 TLDRDTLKNLLTFTNQHNIHLVCDEIYAATVFSTPQFVSIAEIVNDEMRHCNKDLVHIVY 274
Query: 233 SFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEE-SWKAVK 291
S SK + G+R+G V + ++ + + + G V++ Q E L E+ +
Sbjct: 275 SLSKDMGLPGFRIGIVYSFNDTVVSCARKMS-SFGLVSTQTQYLLAEMLSDEKFVSNFLT 333
Query: 292 EMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVF----PSIKDTGMSSEKFSEW--LLE 345
E K +R K L+++ GI+ + + P +K++ +E S W ++
Sbjct: 334 ESSKRLAKRHKHFTNGLEQV-GIKCLRSNAGLFCWMDLRPLLKESNFDAE-MSLWRVIIN 391
Query: 346 KARVVVIPGTAFGKMGEGYVRISYATSREKLME-AMDRMEKALS 388
++ V G++F G+ R+ +A ++ ++ A+ R+ + +S
Sbjct: 392 DVKLNVSKGSSFDCQEPGFFRVFFANMDDETVDIALRRIRRFVS 435
>emb|CAC12206.1| (AL445066) aspartate aminotransferase related protein [Thermoplasma
acidophilum]
Length = 354
Score = 78.4 bits (190), Expect = 1e-13
Identities = 87/391 (22%), Positives = 163/391 (41%), Gaps = 40/391 (10%)
Query: 1 MRQKRKYFIAERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDE 60
++ + I+ ++ K K + + +K N+ + G+ EPD + +D
Sbjct: 2 LQYRSSKMISMEIVEFKWLKFLDRYRSMAK-HNLSNSGMPEPDLRS---------MGIDT 51
Query: 61 GWTHYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVL 120
+ Y + L A+ + + Y VD D NVIIT G E +LA + S + +
Sbjct: 52 RYESYLNE--MVDLDAALRDTVARRYGVDRD--NVIITNGGTEAIFLASAFISASSEVIA 107
Query: 121 IPDPAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGA 180
+P P + + + + R+ L E + K + + ++ PNNPTG
Sbjct: 108 VPSPEYEPIFIVPESLDRRVRRVKL-----------EKIGQAEKNSESLALSLPNNPTGK 156
Query: 181 TLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILANSFSKTFAM 240
D +A + D + Y Y+ DE + F D L +N I++N+ +K + +
Sbjct: 157 YGD--IADLVRDAGRTYR-YVYIDETFHDFTDDRGS---SLYDGSKNLIVSNTMTKFYGL 210
Query: 241 TGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNER 300
+ R+G++V+ E I + ++ N A F +A+ E W +E +
Sbjct: 211 SSLRVGWIVSDKENIDAIRRIKDLTTINNARFSLFLARQAI---EKWDRFRERTHSIVRK 267
Query: 301 RKLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKM 360
+ ++ G E +GA ++F + D SE + + V+V PG+ FG
Sbjct: 268 NADIARKELSDFGFYSDEYEGAPFMF--VGDGRFDSEMMASKAISGYGVLVAPGSYFGL- 324
Query: 361 GEGYVRISYAT--SREKLMEAMDRMEKALSE 389
+GY+R+ +RE + + EK L +
Sbjct: 325 -DGYLRVCLTALDAREDIAAFREFAEKELGK 354
>sp|P23599|1A11_CUCMA 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE CMW33 (ACC SYNTHASE)
(S-ADENOSYL-L-METHIONINE METHYLTHIOADENOSINE-LYASE)
>gi|81570|pir||JQ0926 1-aminocyclopropane-1-carboxylate
synthase (EC 4.4.1.14), wound-induced - winter squash
>gi|217907|dbj|BAA00838.1| (D01032)
1-aminocyclopropane-1-carboxylate synthase [Cucurbita
maxima] >gi|227773|prf||1710321A aminocyclopropane
carboxylate synthase [Cucurbita maxima]
>gi|448306|prf||1916421A aminocyclopropane carboxylate
synthase:ISOTYPE=wound-induced [Cucurbita maxima]
Length = 493
Score = 78.0 bits (189), Expect = 2e-13
Identities = 73/346 (21%), Positives = 147/346 (42%), Gaps = 29/346 (8%)
Query: 70 GIQQLREAVVEYYKKFYD--VDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
G+ + R + + K V D +++ GA + L + GD L+P P +
Sbjct: 97 GLPEFRNGIASFMGKVRGGRVQFDPSRIVMGGGATGASETVIFCLADPGDAFLVPSPYYA 156
Query: 128 SYVEDAKL-AEAKPVRIPLREENNFMPDPDELLELVTKKTRM-------IVINYPNNPTG 179
++ D K A+ +R+ NNF LE+ KK + ++I P+NP G
Sbjct: 157 AFDRDLKWRTRAQIIRVHCNSSNNFQVTK-AALEIAYKKAQEANIKVKGVIITNPSNPLG 215
Query: 180 ATLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPEN-------TILAN 232
T D++ K + ++I+++ DE Y ++ + + E +
Sbjct: 216 TTYDRDTLKTLVTFVNQHDIHLICDEIYSATVFKAPTFISIAQIVEEMEHCKKELIHILY 275
Query: 233 SFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESW--KAV 290
S SK + G+R+G + + ++++ + G V+S Q + A+ S+E + K +
Sbjct: 276 SLSKDMGLPGFRVGIIYSYNDVVVRRAR-QMSSFGLVSSQTQHL-LAAMLSDEDFVDKFL 333
Query: 291 KEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPS----IKDTGMSSE-KFSEWLLE 345
E K ER K L +M GI +V+ +KD +E + ++
Sbjct: 334 AENSKRLAERHARFTKELDKM-GITCLNSNAGVFVWMDLRRLLKDQTFKAEMELWRVIIN 392
Query: 346 KARVVVIPGTAFGKMGEGYVRISYATSREKLME-AMDRMEKALSEL 390
+ ++ V PG++F G+ R+ +A + ++ A++R+ + +
Sbjct: 393 EVKLNVSPGSSFHVTEPGWFRVCFANMDDNTVDVALNRIHSFVENI 438
>pir||E83392 probable transcription regulator PA2032 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9948037|gb|AAG05420.1|AE004629_9 (AE004629) probable
transcriptional regulator [Pseudomonas aeruginosa]
Length = 474
Score = 78.0 bits (189), Expect = 2e-13
Identities = 94/375 (25%), Positives = 157/375 (41%), Gaps = 28/375 (7%)
Query: 33 NVISLGIGEPDFDTPKNIKEACK------RALDEGWTHYTPNAGIQQLREAVVEYYKKFY 86
+V+ LG G PD +P ++K + R D Y G LRE V
Sbjct: 105 DVVQLGRGMPDISSP-SLKPLTRSLARLNRHADARALAYDGIHGSPLLREEVARLLVDS- 162
Query: 87 DVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLR 146
+V+IT G +E ++ ++ E GD V + P+F ++ K K + IP
Sbjct: 163 GCRATASDVVITTGCHEALSVSIRAVCEPGDIVAVESPSFHGAMQSLKGLGMKALEIPTD 222
Query: 147 EENNFMPDPDEL-LELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDE 205
N + EL LE K + N NNP G + + +A+ +AQ Y++ I+ D+
Sbjct: 223 PVNGISLEALELALEQWPIKAIQVTPNC-NNPLGYIMPESRKRALLALAQRYDVAIIEDD 281
Query: 206 PYEHFIYDDAKHYPMLKFAPE-NTILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAY 264
Y Y + + + + +L SFSK A G R+G++V P ++ +
Sbjct: 282 VYGDLAYTYPRPRTIKSYDDDGRVLLCGSFSKVLA-PGLRIGWMV-PGRYADRVLHMKYI 339
Query: 265 IIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEM--PGIRVKEPKGA 322
G A Q+A E + + ++ MR +Y R L++ + G R P+G
Sbjct: 340 STGASALQPQLAIAEFIGNGHYEPHLRRMRAQYQRGRDLMIDWVARYFPEGTRASRPQGG 399
Query: 323 FYVFPSIKDTGMSSEKFSEWLLEKA----RVVVIPGTAFGKMGE--GYVRISYATSREKL 376
F ++ + E F L+KA V V G F G+ +R++YA
Sbjct: 400 FLLWVEL------DEAFDTLRLDKALRNRGVQVAVGCIFSASGKYRNCLRMNYAALPTPA 453
Query: 377 ME-AMDRMEKALSEL 390
+E A+ R+ ++ EL
Sbjct: 454 IEQAVRRVGESACEL 468
>gb|AAA33112.1| (M61195) 1-aminocyclopropane-1-carboxylate synthase [Cucurbita
pepo]
Length = 495
Score = 77.3 bits (187), Expect = 3e-13
Identities = 72/346 (20%), Positives = 151/346 (42%), Gaps = 28/346 (8%)
Query: 70 GIQQLREAVVEYYKKFYD--VDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
G+Q+ R+A+ + K V D +++ GA + L + GD L+P P +
Sbjct: 97 GLQEFRKAMASFMGKVRGGRVKFDPSRIVMGGGATGASETVIFCLADPGDAFLVPSPYYA 156
Query: 128 SYVEDAKL-AEAKPVRIPLREENNFMPDPDELLELVTKKTRM-------IVINYPNNPTG 179
++ D K A+ + + NNF + LE+ KK + ++I P+NP G
Sbjct: 157 AFDRDLKWRTRAQIIPVHCNSSNNFQVT-EAALEIAYKKAQEANMKVKGVIITNPSNPLG 215
Query: 180 ATLDKEVAKAIADIAQDYNIYILSDEPYEHFIY------DDAKHYPMLKFAPENTI-LAN 232
T D++ K + ++I+++ DE Y ++ A+ ++ + I +
Sbjct: 216 TTYDRDTLKTLVTFVNQHDIHLICDEIYSATVFKAPTFTSIAEIVEQMEHCKKELIHILY 275
Query: 233 SFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESW--KAV 290
S SK + G+R+G + + ++++ + G V+S Q + A+ S+E + K +
Sbjct: 276 SLSKDMGLPGFRVGIIYSYNDVVVRRAR-QMSSFGLVSSQTQHL-LAAMLSDEDFVDKFL 333
Query: 291 KEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPS----IKDTGMSSE-KFSEWLLE 345
E K ER + + GI +V+ +KD +E + ++
Sbjct: 334 AENSKRLGERHASRFTKELDKMGITCLNSNAGVFVWMDLRRLLKDQTFKAEMELWRVIIN 393
Query: 346 KARVVVIPGTAFGKMGEGYVRISYATSREKLME-AMDRMEKALSEL 390
+ ++ V PG++F G+ R+ +A + ++ A++R+ + +
Sbjct: 394 EVKLNVSPGSSFHVTEPGWFRVCFANMDDNTVDVALNRIHSFVENI 439
>pir||G75446 probable valine--pyruvate transaminase (EC 2.6.1.66) DR1030
[similarity] - Deinococcus radiodurans (strain R1)
>gi|6458758|gb|AAF10603.1|AE001954_7 (AE001954)
aminotransferase, putative [Deinococcus radiodurans]
Length = 378
Score = 77.3 bits (187), Expect = 3e-13
Identities = 85/373 (22%), Positives = 161/373 (42%), Gaps = 20/373 (5%)
Query: 32 ENVISLGIGEPDFDTP--KNIKEACKRALDEG---WTHYTPNAGIQQLREAVVEYYKKFY 86
E VI+L +G P + +++A +G + Y G LR + Y + Y
Sbjct: 11 EGVINLAVGHPSLHMLPLREMEQAAAHRFAQGNAEFLQYGYEWGDGFLRTELAAYLTREY 70
Query: 87 DVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLR 146
+ E I+ G + L L GD V++ DP + + V P+
Sbjct: 71 GFPVSAEQTFISGGTSQAIDLCCAMLTRPGDTVIVEDPTYFFAFGMFRDHGLNIVTAPVD 130
Query: 147 EENNFMPDPDELLELVTKKTRMIVINYP--NNPTGATLDKEVAKAIADIAQDYNIYILSD 204
E+ D D L LV + +V P NP G TL +E + + +AQ++ IL+D
Sbjct: 131 EQGL---DVDALETLVAQHRPKLVYTIPVHQNPAGVTLPQERREKLVRLAQEHGFTILAD 187
Query: 205 EPYEHFIYDDAKHYPMLKFAPENTILA-NSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHA 263
E Y+ ++ +A +++ SFSK A G RLG++ A ++++ + + A
Sbjct: 188 EVYQLLTFEGTPPPSFAAWADTGQVVSLGSFSKILA-PGTRLGWINAREDVLERLAQNGA 246
Query: 264 YIIGNVASFIQVAGVEA-LRSEESWKAVKEMRKEYNERRKLVLKRLKEMP--GIRVKEPK 320
+ G S + V + L + + ++R+ + R + + L E+ G+ + P
Sbjct: 247 LVSGGGYSPLGGGMVRSMLELGLLPEYIGKLRETFRRRSRALADALDELRPLGLDFQRPT 306
Query: 321 GAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMG--EGYVRISYATSRE-KLM 377
G ++++ ++ G+S+ + L+ V PG F G R+ +A E +L+
Sbjct: 307 GGYFIWVTL-PAGVSATELLPRALDHG-VRFQPGPLFSPNGTQTDKARLCFAFYEEAELV 364
Query: 378 EAMDRMEKALSEL 390
E + R+ + L ++
Sbjct: 365 EGVRRLGEVLRQV 377
>gb|AAC18908.1| (M89931) beta C-S lyase [Corynebacterium glutamicum]
Length = 325
Score = 76.5 bits (185), Expect = 5e-13
Identities = 72/325 (22%), Positives = 140/325 (42%), Gaps = 13/325 (4%)
Query: 65 YTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDP 124
Y P+A L +A+ +Y++ Y + E+V G LA E + G +++P P
Sbjct: 12 YPPDA--TGLNDALTGFYERRYGFGPNPESVFAIPDVVRGLKLAIEHFTKPGSAIIVPLP 69
Query: 125 AFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDK 184
A+ ++E K+ + + I E D E+ + ++ P+NP G +
Sbjct: 70 AYPPFIELPKVTGRQAIYIDAHEY-----DLKEIEKAFADGAGSLLFCNPHNPLGTVFSE 124
Query: 185 EVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYP--MLKFAPENTILANSFSKTFAMTG 242
E + + DIA Y+ I++DE + +Y+ + + A I + SK + G
Sbjct: 125 EYIRELTDIAAKYDARIIADEIHAPLVYEGTHVVAAGVSENAANTCITITATSKAWNTAG 184
Query: 243 WRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRK 302
+ + E + K + I + S + + E + +E + + E + + R
Sbjct: 185 LKCAQIFFSGEADVKAWKNLSDITRDGVSILGLIAAETVYNEGE-EFLDESIQILKDNRD 243
Query: 303 LVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGE 362
L+++ G++V P + ++ T + E S+ L E+ +V++ G AFG
Sbjct: 244 FAAAELEKL-GVKVYAPDSTYLMWLDFAGTKI-EEAPSKILREEGKVMLNDGAAFGGF-T 300
Query: 363 GYVRISYATSREKLMEAMDRMEKAL 387
R+++A SRE L E + R+ L
Sbjct: 301 TCARLNFACSRETLEEGLRRIASVL 325
>pir||T06252 1-aminocyclopropane-1-carboxylate synthase (EC 4.4.1.14) 1 - garden
pea >gi|2360987|gb|AAD04198.1| (AF016458)
1-aminocyclopropane-1-carboxylate synthase; ACC synthase
[Pisum sativum] >gi|2360991|gb|AAB69137.1| (AF016460)
1-aminocyclopropane-1-carboxylate synthase; ACC synthase
[Pisum sativum]
Length = 480
Score = 76.1 bits (184), Expect = 6e-13
Identities = 73/351 (20%), Positives = 156/351 (43%), Gaps = 36/351 (10%)
Query: 70 GIQQLREAVVEYYKKFYD--VDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
G+ ++A+V++ + V D ++++TAGA L E G+ L+P P +
Sbjct: 87 GLPSFKKALVDFMAEIRGNKVTFDPNHIVLTAGATSANETLMFCLAEKGEAFLLPTPYYP 146
Query: 128 SYVEDAKLAEA-KPVRIPLREENNFMPDPDELLEL------VTKKTRMIVINYPNNPTGA 180
+ D K + V I NNF L + K + +++ P+NP G
Sbjct: 147 GFDRDLKWRTGVEIVPIQCTSSNNFQMTESALQQAHEDAKKKNLKVKGVLVTNPSNPLGT 206
Query: 181 TLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENT------------ 228
T+ K + D +D N++++SDE Y ++ +++ E T
Sbjct: 207 TMSKNELNLLIDFIKDKNMHLISDEIYSGTVFTSPNFVSVMEILNERTDKDFLDANVSER 266
Query: 229 -ILANSFSKTFAMTGWRLGFVVAPSE-IIKEMIKLHAYIIGNVASFIQVAGVEALRSEES 286
+ S SK + G+R+G + + +E ++ K+ ++ G V+S Q + A+ ++
Sbjct: 267 VHIVYSLSKDLGLPGFRVGAIYSDNETVVAAATKMSSF--GLVSSQTQYL-LSAMLGDKK 323
Query: 287 W--KAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSE--- 341
+ + E +K +R+K+++ L++ +K + + +++ ++S+ F
Sbjct: 324 FTRNYLSENQKRLKKRQKMLVNGLQKAGISCLKTNNAGLFCWVDMRNL-LTSDTFEAEMD 382
Query: 342 -W--LLEKARVVVIPGTAFGKMGEGYVRISYAT-SREKLMEAMDRMEKALS 388
W +L + + + PG++ G+ R+ +A S + L AM R++ +S
Sbjct: 383 LWKKILYEVGLNISPGSSCHCTEPGWFRVCFANMSEDTLNLAMKRLKDFVS 433
>sp|Q00257|1A12_CUCMA 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE CMA101 (ACC SYNTHASE)
(S-ADENOSYL-L-METHIONINE METHYLTHIOADENOSINE-LYASE)
>gi|625967|pir||JQ2214 1-aminocyclopropane-1-carboxylate
synthase (EC 4.4.1.14), auxin-induced - winter squash
>gi|217905|dbj|BAA00839.1| (D01033)
1-aminocyclopropane-1-carboxylate synthase [Cucurbita
maxima] >gi|1022841|gb|AAA91152.1| (U37774)
1-aminocyclopropane-1-carboxylic acid synthase
[Cucurbita maxima] >gi|448307|prf||1916421B
aminocyclopropane carboxylate
synthase:ISOTYPE=auxin-induced [Cucurbita maxima]
Length = 475
Score = 75.7 bits (183), Expect = 8e-13
Identities = 73/350 (20%), Positives = 157/350 (44%), Gaps = 34/350 (9%)
Query: 70 GIQQLREAVVEYYKKFYD--VDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
G+ ++A+VE+ + V + N+++TAGA L E+GD L+P P +
Sbjct: 87 GLPAFKKALVEFMAEIRGNKVSFEANNIVLTAGATSANETLMFCLAEAGDAFLLPTPYYP 146
Query: 128 SYVEDAK-LAEAKPVRIPLREENNFMPDPDEL----LELVTKKTRM--IVINYPNNPTGA 180
+ D K + V I N F L + T+ R+ +++ P+NP G
Sbjct: 147 GFDRDLKWRTGVEIVPIHCTSSNGFQITQSALEQAYKDAQTRNLRVKGVLVTNPSNPLGT 206
Query: 181 TLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTI----------L 230
T++++ + D I+++SDE Y ++ ++ E + +
Sbjct: 207 TMNRDELNLVFDFITSKGIHLISDEIYSGTVFGSPGFVSAMEVLKERSSEDEEVWKRVHI 266
Query: 231 ANSFSKTFAMTGWRLGFVVAPSE-IIKEMIKLHAYIIGNVASFIQVAGVEALRSEESW-- 287
S SK + G+R+G + + + ++ K+ ++ G V+S Q + A+ S++ +
Sbjct: 267 VYSLSKDLGLPGFRVGAIYSNDDMVVAAATKMSSF--GLVSSQTQYL-LSAMLSDKKFTI 323
Query: 288 KAVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKA 347
+ E +K +R+K+++ L++ GI + + + ++ + S+KF L
Sbjct: 324 SYISENQKRLKQRQKMLVSGLQK-AGINCLDSNAGLFCWVDMRHL-LESDKFESELELWK 381
Query: 348 RVV------VIPGTAFGKMGEGYVRISYATSREKLME-AMDRMEKALSEL 390
++V + PG++ G+ R+ +A E ++ A+ R++ ++EL
Sbjct: 382 KIVYEVGLNISPGSSCHCTEPGWFRVCFANMSESTLKLAVRRLKSFVTEL 431
>pir||T09658 1-aminocyclopropane-1-carboxylate synthase (EC 4.4.1.14) -
muskmelon >gi|695402|dbj|BAA06464.1| (D30805)
1-aminocyclopropane-1-carboxylate synthase [Cucumis
melo] >gi|5811577|dbj|BAA83618.1| (AB025906)
1-aminocyclopropane-1-carboxylate synthase [Cucumis
melo]
Length = 493
Score = 75.7 bits (183), Expect = 8e-13
Identities = 74/346 (21%), Positives = 151/346 (43%), Gaps = 29/346 (8%)
Query: 70 GIQQLREAVVEYYKKFYD--VDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
G+ + R A+ + K V D +++ GA + L + GD LIP P +
Sbjct: 97 GLPEFRNAIASFMGKARGGRVKFDPSRIVMGGGATGASETVIFCLADPGDAFLIPSPYYA 156
Query: 128 SYVEDAKL-AEAKPVRIPLREENNFMPDPDELLELVTKKT-------RMIVINYPNNPTG 179
++ D + A+ + + NNF E LE+ KK + ++I P+NP G
Sbjct: 157 AFDRDLQWRTRAQIIPVHCNSSNNFQITR-EALEVAYKKAEESNIKVKGLIITNPSNPLG 215
Query: 180 ATLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPEN-------TILAN 232
D++ K++ + D NI+++ DE Y ++ + + E + +
Sbjct: 216 TIYDRDTLKSLVNFVNDNNIHLICDEIYSATVFKSPSFTSIAEIIEEMDHCKKELIHILS 275
Query: 233 SFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESW--KAV 290
S SK + G+R+G + + ++ + + + + G V+S Q + A+ S+E + +
Sbjct: 276 SLSKDMGLPGFRVGILYSYNDTVVSIARKMS-SFGLVSSQTQHL-LAAMLSDEEFVDNFL 333
Query: 291 KEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPS----IKDTGMSSE-KFSEWLLE 345
E K +R + L++M GI +V+ +KD SE + ++
Sbjct: 334 VENSKRLAKRHARFTEELEKM-GITCLNSNAGLFVWMDLRKLLKDQSFESEMELWRVIIN 392
Query: 346 KARVVVIPGTAFGKMGEGYVRISYATSREKLM-EAMDRMEKALSEL 390
+ ++ V PG++F G+ R+ +A + + A+DR+ + ++
Sbjct: 393 EVKLNVSPGSSFHVTEPGWFRVCFANMDDNTVGVALDRIHSFVGKI 438
>dbj|BAA93712.1| (AB032935) 1-aminocyclopropane-1-carboxylate synthase [Cucumis
melo]
Length = 493
Score = 75.7 bits (183), Expect = 8e-13
Identities = 74/346 (21%), Positives = 151/346 (43%), Gaps = 29/346 (8%)
Query: 70 GIQQLREAVVEYYKKFYD--VDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
G+ + R A+ + K V D +++ GA + L + GD LIP P +
Sbjct: 97 GLPEFRNAIASFMGKARGGRVKFDPSRIVMGGGATGASETVIFCLADPGDAFLIPSPYYA 156
Query: 128 SYVEDAKL-AEAKPVRIPLREENNFMPDPDELLELVTKKT-------RMIVINYPNNPTG 179
++ D + A+ + + NNF E LE+ KK + ++I P+NP G
Sbjct: 157 AFDRDLQWRTRAQIIPVHCNSSNNFQITR-EALEVAYKKAEESNIKVKGLIITNPSNPLG 215
Query: 180 ATLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPEN-------TILAN 232
D++ K++ + D NI+++ DE Y ++ + + E + +
Sbjct: 216 TIYDRDTLKSLVNFVNDNNIHLICDEIYSATVFKSPSFTSIAEIIEEMDHCKKELIHILS 275
Query: 233 SFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESW--KAV 290
S SK + G+R+G + + ++ + + + + G V+S Q + A+ S+E + +
Sbjct: 276 SLSKDMGLPGFRVGILYSYNDTVVSIARKMS-SFGLVSSQTQHL-LAAMLSDEEFVDNFL 333
Query: 291 KEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPS----IKDTGMSSE-KFSEWLLE 345
E K +R + L++M GI +V+ +KD SE + ++
Sbjct: 334 VENSKRLAKRHARFTEELEKM-GITCLNSNAGLFVWMDLRKLLKDQSFESEMELWRVIIN 392
Query: 346 KARVVVIPGTAFGKMGEGYVRISYATSREKLM-EAMDRMEKALSEL 390
+ ++ V PG++F G+ R+ +A + + A+DR+ + ++
Sbjct: 393 EVKLNVSPGSSFHVTEPGWFRVCFANMDDNTVGVALDRIHSFVGKI 438
>emb|CAB56665.1| (AL121596) aminotransferase [Streptomyces coelicolor A3(2)]
Length = 401
Score = 74.9 bits (181), Expect = 1e-12
Identities = 77/364 (21%), Positives = 151/364 (41%), Gaps = 18/364 (4%)
Query: 33 NVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNAGIQQLREAVVEYYKKFYDVDIDV 92
+++ I + DF+T + A + L+ G Y+ A+V +Y + +D
Sbjct: 44 DLLPFTISDMDFETAPEVLAALRGRLEHGVLGYS-RWRQDDFLSAIVHWYAARHGTAVDP 102
Query: 93 ENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREENNFM 152
+V+ GD V+ P + ++ + + + PL +
Sbjct: 103 GSVVYAPSVVYQVSRLLHLWSRPGDGVVAHTPMYDAFPRTVAASGRRLLECPLDD----W 158
Query: 153 PDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYEHFIY 212
P+ + LL L T ++++ P+NPTG +A + + + ++SDE + +
Sbjct: 159 PELERLLAL--PDTAVLLLCSPHNPTGRVWSAAELDRMARLCARHGVAVVSDEIHSDLAH 216
Query: 213 DDAKHYPMLKFAPENT-ILANSFSKTF---AMTGWRLGFVVAPSEIIKEMIKLH-AYIIG 267
H P ++ A + + S SK+F A+TG G + P+ + +L A +
Sbjct: 217 APHLHRPWVRHAGDGRWAVVTSASKSFNIPALTG-SYGIIGDPASRDAYLRQLKDADGLS 275
Query: 268 NVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKE-MPGIRVKEPKGAFYVF 326
+ A V + A R W + +R +V RL+ PG+ + P+ + +
Sbjct: 276 SPAVLSLVGHIAAYREGAPW--LDALRTYLAGNLAMVADRLRAAFPGLDWRPPQAGYLAW 333
Query: 327 PSIKDTGMSSEKFSEWLLEKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAMDRMEKA 386
++ G+ E+ L+E +V V+PG A+G G VR++ R K ++ + +A
Sbjct: 334 IDLRPLGVDDEELQRELVEVEKVAVMPGAAYGSPGR--VRLNVGCPRSKAEAGVEALVRA 391
Query: 387 LSEL 390
L L
Sbjct: 392 LGRL 395
>emb|CAB01401.1| (Z77854) 1-aminocyclopropane-carboxylate synthase homologue
[Phalaenopsis sp.]
Length = 445
Score = 74.5 bits (180), Expect = 2e-12
Identities = 73/345 (21%), Positives = 149/345 (43%), Gaps = 30/345 (8%)
Query: 70 GIQQLREAVVEYYKKFYD--VDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
G+Q R+A+ ++ V + + +++TAGA L L + GD VL+P P +
Sbjct: 93 GLQSFRKAMASLMEQIRGKRVKFNPDRMVLTAGATAANELLTFILADPGDAVLVPTPYYP 152
Query: 128 SYVEDAKLAEA-KPVRIPLREENNF------MPDPDELLELVTKKTRMIVINYPNNPTGA 180
+ D + K + N F + + E + + ++I P+NP G
Sbjct: 153 GFDRDLQWRTGVKIFPVHCHSSNGFQLTLPSLQSAYSIAEASNLRVKALLITNPSNPLGT 212
Query: 181 TLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAP-------ENTILANS 233
T+ + + + I + NI+++SDE Y ++ + + + + + S
Sbjct: 213 TMPRSLLEDILNFISQKNIHLISDEIYSGSVFSSPEFISVAEVVEASQHKNCDGVHIVYS 272
Query: 234 FSKTFAMTGWRLGFVVAPSE-IIKEMIKLHAYIIGNVASFIQVAGVEALRSEE-SWKAVK 291
SK + G+R+G + + ++ ++ ++ ++ + V+S Q L EE + K +K
Sbjct: 273 LSKDLGLPGFRVGTIYSYNDRVVTTARRMSSFSL--VSSQTQKMLASMLSDEEFTVKYIK 330
Query: 292 EMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSE-----W--LL 344
R+ R +++ LK+ GI E + + ++ T M EK E W +L
Sbjct: 331 TNRERLRRRHGYIVEGLKD-AGIECLEGNAGLFCWMNL--TQMLEEKSMEGELRLWKMIL 387
Query: 345 EKARVVVIPGTAFGKMGEGYVRISYATSREKLMEAMDRMEKALSE 389
+ ++ V PG++ G+ R+ +A ++ +E R K E
Sbjct: 388 SEVKLNVSPGSSCYCAEPGWFRVCFANMTKETLEVALRRTKDFVE 432
>dbj|BAA33374.1| (AB006803) ACC synthase [Cucumis sativus]
>gi|7416126|dbj|BAA93714.1| (AB032937)
1-aminocyclopropane-1-carboxylate synthase [Cucumis
sativus]
Length = 493
Score = 73.4 bits (177), Expect = 4e-12
Identities = 84/403 (20%), Positives = 171/403 (41%), Gaps = 42/403 (10%)
Query: 25 FERASKMENVISLGIGEPDFDTPKNIKEACKR------ALDEGWTHYTPNA------GIQ 72
F + VI +G+ E +P + + K+ DEG ++ A G+
Sbjct: 41 FHPENNPSGVIQMGLAENQL-SPDLLVDWIKKHPKASICTDEGLLNFKDIANFQDYHGLP 99
Query: 73 QLREAVVEYYKKFYD--VDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYV 130
+ R A+ + K V D +++ GA + L + GD LIP P + ++
Sbjct: 100 EFRNAIASFMGKARGGRVKFDPSRIVMGGGATGASEAVIFCLADPGDAFLIPSPYYAAFD 159
Query: 131 EDAKL-AEAKPVRIPLREENNFMPDPDELLELVTKKT-------RMIVINYPNNPTGATL 182
D + A+ + + NNF E LE+ KK + ++I P+NP G
Sbjct: 160 RDLQWRTRAQIIPVHCNSSNNFQITR-EALEVAYKKAEESNIKVKGLIITNPSNPLGTIY 218
Query: 183 DKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPEN-------TILANSFS 235
D++ K++ + D NI+++ DE Y ++ + + E + +S S
Sbjct: 219 DRDTLKSLVNFVNDNNIHLVCDEIYCATVFKSPSFISIAEIIEEMDHCKKELIHILSSLS 278
Query: 236 KTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESW--KAVKEM 293
K + G+R+G + + ++ + + + + G V+S Q + A+ S++ + + E
Sbjct: 279 KDMELPGFRVGILYSYNDTVVSIARKMS-SFGLVSSQTQHL-LAAMLSDDEFVDNFLVEN 336
Query: 294 RKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPS----IKDTGMSSE-KFSEWLLEKAR 348
K +R K L++M GI +V+ +KD SE + ++ + +
Sbjct: 337 SKRLAKRHARFTKELEKM-GITCLNGNAGLFVWMDLRKLLKDQSFESEMELWRVIINEVK 395
Query: 349 VVVIPGTAFGKMGEGYVRISYATSREKLME-AMDRMEKALSEL 390
+ V PG++F G+ R+ +A + ++ A+ R+ + ++
Sbjct: 396 LNVSPGSSFRVTEPGWFRVCFANMDDNTVDVALGRIHSFVGKI 438
>pir||T10889 1-aminocyclopropane-1-carboxylate synthase (EC 4.4.1.14) 6 - mung
bean >gi|1813331|dbj|BAA19161.1| (AB000679)
1-aminocyclopropane-1-carboxylate synthase [Vigna
radiata] >gi|3769286|dbj|BAA33859.1| (AB018355)
1-aminocyclopropane-1-carboxylate synthase [Vigna
radiata]
Length = 472
Score = 73.0 bits (176), Expect = 6e-12
Identities = 71/350 (20%), Positives = 152/350 (43%), Gaps = 32/350 (9%)
Query: 70 GIQQLREAVVEYYKKFYD--VDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
G+ ++A+V++ + V D ++++TAG+ L E GD L+P P +
Sbjct: 87 GLPSFKKALVDFMAEIRGNKVTFDPNHIVLTAGSTSANQTLMFCLAELGDAFLLPTPYYP 146
Query: 128 SYVEDAKLAEA-KPVRIPLREENNFMPDPDELLELVTK------KTRMIVINYPNNPTGA 180
+ D K + V I NNF L + + + + +++ P+NP G
Sbjct: 147 GFDRDLKWRTGVEIVPIQCTSSNNFQITEAALKQAYQEAKKRNLRVKGVLVTNPSNPLGT 206
Query: 181 TLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILAN-------- 232
T+ + + D +D N++++SDE Y +Y+ +++ + L +
Sbjct: 207 TMSRSELNLLVDFIKDKNMHLISDEIYSGTVYNSPGFVSIMEILKDRNDLKDCGANVWDR 266
Query: 233 -----SFSKTFAMTGWRLGFVVAPSE-IIKEMIKLHAYIIGNVASFIQVAGVEALRSEES 286
S SK + G+R+G + + +E ++ K+ ++ G V+S Q L ++
Sbjct: 267 VHIVYSLSKDLGLPGFRVGAIYSENEVVVAAATKMSSF--GLVSSQTQYLLSAMLGDKKF 324
Query: 287 WK-AVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIK-----DTGMSSEKFS 340
K + E K R++ ++ L++ +K + + ++ +T + +
Sbjct: 325 TKNYISENLKRLKRRQRNLVSGLQKAGISCLKTNNAGLFCWVDMRHLLHSNTFEAEMELW 384
Query: 341 EWLLEKARVVVIPGTAFGKMGEGYVRISYAT-SREKLMEAMDRMEKALSE 389
+ +L + R+ + PG++ G+ R+ +A S E L AM R++ + E
Sbjct: 385 KKILYEVRLNISPGSSCHCTEPGWFRMCFANMSEETLNLAMKRLKTFVQE 434
>pir||E75378 probable valine--pyruvate transaminase (EC 2.6.1.66) DR1588
[similarity] - Deinococcus radiodurans (strain R1)
>gi|6459351|gb|AAF11148.1|AE002002_6 (AE002002)
aminotransferase, class I, putative [Deinococcus
radiodurans]
Length = 420
Score = 73.0 bits (176), Expect = 6e-12
Identities = 88/397 (22%), Positives = 174/397 (43%), Gaps = 40/397 (10%)
Query: 9 IAERVILIKRSKIRELFERASKMENVISL--GIGEPDFDTPKNIKEACKRALDE---GWT 63
I+ R + S IRE+ + ++ +VIS G+ P+ +++A + AL +
Sbjct: 27 ISRRAQTMTASAIREIL-KITQQPDVISFAGGLPAPELFPLDAVRQAAETALSKYGPAAL 85
Query: 64 HYTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPD 123
Y+ G LRE + + I NV I G+ +G L + L++ GD VL+
Sbjct: 86 QYSTTEGHLPLREWIAGRH------GIPAANVQIVTGSQQGLDLLGKILIDEGDLVLVEA 139
Query: 124 PAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVT-------KKTRMIVINYPNN 176
P ++ ++ + + +P E D D L L+ K + I N
Sbjct: 140 PTYLGALQSFQPYLPRYAEMPTDEGGI---DVDALATLLAGLAAQGEKPKLLYAIPNFQN 196
Query: 177 PTGATLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPE--------NT 228
PTG TL E + + ++ Y + ++ D+PY + + + E +
Sbjct: 197 PTGRTLSLERRRRLVELTAQYGVLVIEDDPYGQLRFSGEALPSLYEIGLELAGDVDRNHV 256
Query: 229 ILANSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWK 288
I ++SFSKT + G R +V A + +I ++I+ + + Q+ E L +
Sbjct: 257 IYSSSFSKTL-VPGLRDAWVEAAAPVITKLIQAKQGADLHTPTLNQMMITELLPLLPA-- 313
Query: 289 AVKEMRKEYNERRKLVLKRLKEM--PGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEK 346
++ ++ Y ER +L ++ E G+ P+G +++ ++ + G+ + +E
Sbjct: 314 QIETVKAAYRERGAHMLSQMDEFFPAGVTYTRPQGGMFLWVTLPE-GVDTVALLPRAVEN 372
Query: 347 ARVVVIPGTAFGKMGEG--YVRISYATSR-EKLMEAM 380
+V +PG F +G G +R+SY+++ E++ + M
Sbjct: 373 -KVAYVPGQPFFALGGGANTMRMSYSSATPEQITQGM 408
>dbj|BAA33376.1| (AB006805) ACC synthase [Cucumis sativus]
Length = 481
Score = 72.6 bits (175), Expect = 7e-12
Identities = 68/348 (19%), Positives = 150/348 (42%), Gaps = 30/348 (8%)
Query: 70 GIQQLREAVVEYYKKFYD--VDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
G+ ++A+VE+ + V + N+++TAGA L E+GD L+P P +
Sbjct: 87 GLPAFKKALVEFMAEIRGNKVTFEANNIVLTAGATSANETLMFCLAEAGDAFLLPTPYYP 146
Query: 128 SYVEDAK-LAEAKPVRIPLREENNFMPDPDELLELVTK------KTRMIVINYPNNPTGA 180
+ D K + V I N F L + + + + +++ P+NP G
Sbjct: 147 GFDRDLKWRTGVEIVPIHCTSSNGFQVTQPALEQAYQEAQARNLRVKGVLVTNPSNPLGT 206
Query: 181 TLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENT----------IL 230
T+ + + D I+++SDE Y ++ ++ E + +
Sbjct: 207 TMTRNELDLVFDFITSKGIHLISDEIYSGTVFGSPGFVSAMEVLKERSNEDEEVWKRVHI 266
Query: 231 ANSFSKTFAMTGWRLGFVVAPSE-IIKEMIKLHAY-IIGNVASFIQVAGVEALRSEESWK 288
S SK + G+R+G + + E ++ K+ ++ ++ + ++ A + + ++
Sbjct: 267 VYSLSKDLGLPGFRVGAIYSNDEMVVAAATKMSSFGLVSSQTHYLLSAMLSDKKFTRTY- 325
Query: 289 AVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIK-----DTGMSSEKFSEWL 343
+ E +K +R+K+++ L E GI+ E + + ++ DT K + +
Sbjct: 326 -ISENQKRLKQRQKMLVSGL-EKAGIKCLESSAGLFCWVDMRHLLESDTFECELKLWKKI 383
Query: 344 LEKARVVVIPGTAFGKMGEGYVRISYAT-SREKLMEAMDRMEKALSEL 390
+ + + + PG++ G+ R+ +A S+ L A+ R++ + EL
Sbjct: 384 VYEVGLNISPGSSCHCTEPGWFRVCFANMSQSTLKLAIRRLKSFVQEL 431
>pir||E83130 conserved hypothetical protein PA4132 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9950336|gb|AAG07519.1|AE004829_9 (AE004829)
conserved hypothetical protein [Pseudomonas aeruginosa]
Length = 471
Score = 72.6 bits (175), Expect = 7e-12
Identities = 72/316 (22%), Positives = 143/316 (44%), Gaps = 29/316 (9%)
Query: 90 IDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVEDAKLAEAKPVRIPLREEN 149
+ VE ++I+ GA E L + + GD V I PAF + ++ + + K V IP+
Sbjct: 167 LPVEELVISNGALEALNLCLQVVTRPGDLVAIEAPAFYATLQVLERLKLKAVEIPVHPRE 226
Query: 150 NF-MPDPDELLELVTKKTRMIVINYPNNPTGATLDKEVAKAIADIAQDYNIYILSDEPYE 208
+ + LE + K + N+ NP GA++D E +A+A++ + + ++ D+ Y
Sbjct: 227 GIDLEVLADSLERLPIKACWFMSNF-QNPMGASMDDEKKRALAELLARHQVPMIEDDVYA 285
Query: 209 HFIYDDAKHYPMLKFAPENTIL-ANSFSKTFAMTGWRLGFVVA-----PSEIIKEMIKLH 262
+ P+ + E ++ +SFSK+ A G+R+G+V E +K M L
Sbjct: 286 ELYFGQQAPKPVKAYDQEGLVMHCSSFSKSLA-PGYRVGWVAGGRYAEQIERLKLMTSLS 344
Query: 263 AYIIGN--VASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLKRLKEM--PGIRVKE 318
A I +A ++Q G + + ++++R ++ +L + RV
Sbjct: 345 ASIPAQAAIADYLQHGGYD--------RHLRKLRYALETQQNAMLAAVARYFPEQTRVSR 396
Query: 319 PKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFG--KMGEGYVRISY----ATS 372
P G ++++ + + S F L + + + PG F + R++Y +
Sbjct: 397 PSGGYFLWLELPEAVDSLRLFQLALAQ--GISLAPGPIFSATRRFAHCARLNYGHPWSAR 454
Query: 373 REKLMEAMDRMEKALS 388
+EK ME + R+ ++L+
Sbjct: 455 QEKAMETLGRITQSLA 470
>gb|AAC63850.1| (U73786) ACC synthase [Arabidopsis thaliana]
Length = 466
Score = 70.6 bits (170), Expect = 3e-11
Identities = 74/344 (21%), Positives = 151/344 (43%), Gaps = 25/344 (7%)
Query: 70 GIQQLREAVVEYYKKFYD--VDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
G+ + R+AV ++ +K + V D + ++++ GA L GD L+P P +
Sbjct: 69 GLPEFRQAVAKFMEKTRNNKVKFDPDRIVMSGGATGAHETVAFCLANPGDGFLVPTPYYP 128
Query: 128 SYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRM-------IVINYPNNPTGA 180
+ D + + +N E LE + R +++ P+NP G
Sbjct: 129 GFDRDLRWRTGVNLVPVTCHSSNGFKITVEALEAAYENARKSNIPVKGLLVTNPSNPLGT 188
Query: 181 TLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPE----NTILAN---S 233
TLD+E K++ + D I++++DE Y + ++ + + E N L + S
Sbjct: 189 TLDRECLKSLVNFTNDKGIHLIADEIYAATTFGQSEFISVAEVIEEIEDCNRDLIHIVYS 248
Query: 234 FSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESW-KAVKE 292
SK + G R+G V + ++ + ++ + + G V+S Q + L EE + ++E
Sbjct: 249 LSKDMGLPGLRVGIVYSYNDRVVQIARKMS-SFGLVSSQTQHLIAKMLSDEEFVDEFIRE 307
Query: 293 MRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIKD---TGMSSEKFSEW--LLEKA 347
+ R + L + GI + K +++ +++ T + W ++ +
Sbjct: 308 SKLRLAARHAEITTGLDGL-GIGWLKAKAGLFLWMDLRNLLKTATFDSETELWRVIVHQV 366
Query: 348 RVVVIPGTAFGKMGEGYVRISYATSREKLME-AMDRMEKALSEL 390
++ V PG +F G+ R+ +A K ME A++R++ S+L
Sbjct: 367 KLNVSPGGSFHCHEPGWFRVCFANMDHKTMETALERIKVFTSQL 410
>gb|AAA78273.1| (U34986) 1-aminocyclopropane-1-carboxylic acid synthase [Vigna
radiata]
Length = 472
Score = 70.2 bits (169), Expect = 4e-11
Identities = 70/350 (20%), Positives = 152/350 (43%), Gaps = 32/350 (9%)
Query: 70 GIQQLREAVVEYYKKFYD--VDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
G+ ++A+V++ + V D ++++TAG+ L E GD L+P P +
Sbjct: 87 GLPSFKKALVDFMAEIRGNKVTFDPNHIVLTAGSTSANETLMFCLAELGDAFLLPTPYYP 146
Query: 128 SYVEDAKLAEA-KPVRIPLREENNFMPDPDELLELVTK------KTRMIVINYPNNPTGA 180
+ D K + V I NNF L + + + + +++ P+NP G
Sbjct: 147 GFDRDLKWRTGVEIVPIQCTSSNNFQITEAALKQAYQEAKKRNLRVKGVLVTNPSNPLGT 206
Query: 181 TLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTILAN-------- 232
T+ + + D +D N++++SDE Y +Y+ +++ + L +
Sbjct: 207 TMSRSELNLLVDFIKDKNMHLISDEIYSGTVYNSPGFVSIMEILKDRNDLKDCGANVWDR 266
Query: 233 -----SFSKTFAMTGWRLGFVVAPSE-IIKEMIKLHAYIIGNVASFIQVAGVEALRSEES 286
S SK + G+R+G + + +E ++ K+ ++ G V+S Q L ++
Sbjct: 267 VHIVYSLSKDLGLPGFRVGAIYSENEVVVAAATKMSSF--GLVSSQTQYLLSAMLGDKKF 324
Query: 287 WK-AVKEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIK-----DTGMSSEKFS 340
K + E K R++ ++ L++ +K + + ++ +T + +
Sbjct: 325 TKNYISENLKRLKRRQRNLVSGLQKAGISCLKTNNAGLFCWVDMRHLLHSNTFEAEMELW 384
Query: 341 EWLLEKARVVVIPGTAFGKMGEGYVRISYAT-SREKLMEAMDRMEKALSE 389
+ +L + R+ + PG++ G+ R+ +A S E L AM+ ++ + E
Sbjct: 385 KKILYQERLNISPGSSCHCTEPGWFRMCFANMSEETLNLAMNGLKTFVQE 434
>pir||T13019 1-aminocyclopropane-1-carboxylate synthase (EC 4.4.1.14) ACS-6 -
Arabidopsis thaliana >gi|5596474|emb|CAB51412.1|
(AL096882) ACC synthase (AtACS-6) [Arabidopsis thaliana]
>gi|7267827|emb|CAB81229.1| (AL161531) ACC synthase
(AtACS-6) [Arabidopsis thaliana]
Length = 495
Score = 70.2 bits (169), Expect = 4e-11
Identities = 74/344 (21%), Positives = 150/344 (43%), Gaps = 25/344 (7%)
Query: 70 GIQQLREAVVEYYKKFYD--VDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
G+ + R+AV ++ +K + V D + ++++ GA L GD L+P P +
Sbjct: 98 GLPEFRQAVAKFMEKTRNNKVKFDPDRIVMSGGATGAHETVAFCLANPGDGFLVPTPYYP 157
Query: 128 SYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRM-------IVINYPNNPTGA 180
+ D + + +N E LE + R +++ P+NP G
Sbjct: 158 GFDRDLRWRTGVNLVPVTCHSSNGFKITVEALEAAYENARKSNIPVKGLLVTNPSNPLGT 217
Query: 181 TLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPE----NTILAN---S 233
TLD+E K++ + D I++++DE Y + ++ + + E N L + S
Sbjct: 218 TLDRECLKSLVNFTNDKGIHLIADEIYAATTFGQSEFISVAEVIEEIEDCNRDLIHIVYS 277
Query: 234 FSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESW-KAVKE 292
SK + G R+G V + ++ + ++ + + G V+S Q + L EE + ++E
Sbjct: 278 LSKDMGLPGLRVGIVYSYNDRVVQIARKMS-SFGLVSSQTQHLIAKMLSDEEFVDEFIRE 336
Query: 293 MRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIKD---TGMSSEKFSEW--LLEKA 347
+ R + L + GI + K +++ +++ T + W ++ +
Sbjct: 337 SKLRLAARHAEITTGLDGL-GIGWLKAKAGLFLWMDLRNLLKTATFDSETELWRVIVHQV 395
Query: 348 RVVVIPGTAFGKMGEGYVRISYATSREKLME-AMDRMEKALSEL 390
++ V PG +F G+ R+ +A K ME A++R+ S+L
Sbjct: 396 KLNVSPGGSFHCHEPGWFRVCFANMDHKTMETALERIRVFTSQL 439
>pir||G82405 transcription regulator GntR family VCA0871 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9658304|gb|AAF96769.1| (AE004415) transcriptional
regulator, GntR family [Vibrio cholerae]
Length = 473
Score = 70.2 bits (169), Expect = 4e-11
Identities = 78/330 (23%), Positives = 145/330 (43%), Gaps = 24/330 (7%)
Query: 70 GIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSY 129
G Q LR + + Y+K +++ ++++IT+GA E L +S + GD V I PAF
Sbjct: 148 GSQTLRRQIAQRYQKS-GLNVLPDDIVITSGAMEALNLCLQSCTKPGDLVAIEYPAFYGV 206
Query: 130 VEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKK--TRMIVINYPNNPTGATLDKEVA 187
++ + V IP + D D L + + + NP G ++ +
Sbjct: 207 LQAIERLNLTAVEIPTDPRDGI--DLDVLASVFSSMDIKACWFMTESQNPLGYSMSETNK 264
Query: 188 KAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKF-APENTILANSFSKTFAMTGWRLG 246
+ +A++ Y I ++ D+ Y + P + N +L SFSK+ + G+R+G
Sbjct: 265 QRLAELVNHYQIPMIEDDVYRELGIGNPSSLPAKAYDKVGNILLCGSFSKSLS-PGFRIG 323
Query: 247 FVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKLVLK 306
+VVA + H + + IQ+ L +K++RK NER+K +
Sbjct: 324 WVVAGERALNIQRLQHLSTLSSSIP-IQLGLSHYLTFYNFDHHLKKLRKLLNERKKAHAE 382
Query: 307 RLKE-MP-GIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAFG--KMGE 362
L+ +P ++ G ++++ + T + +E E LE + + PG F K
Sbjct: 383 LLRTYLPHNTKIHLNNGGYFIWVELPQT-IYAETLYEQALEH-NIAIAPGILFSSDKRFS 440
Query: 363 GYVRI--SYATSREKLMEAMDRMEKALSEL 390
++R+ SYA +R+E+A+ L
Sbjct: 441 HHIRLNCSYACD--------ERIEQAIQTL 462
>pir||H83282 probable transcriptional regulator PA2897 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9948989|gb|AAG06285.1|AE004716_3 (AE004716) probable
transcriptional regulator [Pseudomonas aeruginosa]
Length = 479
Score = 70.2 bits (169), Expect = 4e-11
Identities = 74/357 (20%), Positives = 151/357 (41%), Gaps = 17/357 (4%)
Query: 11 ERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTHYTPNA- 69
ER L+ RS I S+ E V LG P D A + L + +P A
Sbjct: 86 ERPGLVTRSSIINQVLAESRREGVFPLGAAVPHVDYLP--VRALHQQLAKVTRFQSPRAF 143
Query: 70 ------GIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPD 123
G + LR V + V +D V IT G + ++A L GD +
Sbjct: 144 SYMFSPGFEPLRRQVAIRMRDA-GVVVDPSQVTITHGCVDAIHMALRVLTRPGDLIATES 202
Query: 124 PAFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLD 183
P++ ++ A + K + IP + +L +++ +NP G T+
Sbjct: 203 PSYYGLLQLADVLGLKVIEIPSDPRTGISLEALQLAANQWSIKALVLTARLSNPFGGTIP 262
Query: 184 KEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENTIL-ANSFSKTFAMTG 242
++ K + + ++NI ++ D+ Y ++D + + + ++ +SFSKT + G
Sbjct: 263 EDRQKQLLKLTAEHNIGVVEDDIYGELMFDQGQARSLKSHDRDGRVIYCSSFSKTIS-PG 321
Query: 243 WRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRK 302
R+G+++A +E+ +L + + + Q+ L + + ++ +R+EY +
Sbjct: 322 VRIGWIIA-ERYQEEIRRLQTFTTHSACTVTQMGVAAYLENGGYDRHLRYIRQEYRKNMT 380
Query: 303 LVLKRLKEM--PGIRVKEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAF 357
+++ G ++ PKG F ++ S+ +++++ LE+ + + PG F
Sbjct: 381 AYQLAVQQYFPEGTQMTRPKGGFILWVSL-PAKVNTKELHVRALEQG-ISIAPGLIF 435
>gb|AAF22112.1|AF119414_1 (AF119414) 1-aminocyclopropane-1-carboxylate synthase 5 [Lupinus
albus]
Length = 448
Score = 69.9 bits (168), Expect = 5e-11
Identities = 78/403 (19%), Positives = 170/403 (41%), Gaps = 42/403 (10%)
Query: 25 FERASKMENVISLGIGEPD--FDTPKNIKEACKRALD--EGWTHYTPNA------GIQQL 74
+ + VI +G+ E FD + E A +G + NA G++
Sbjct: 39 YHEITNPSGVIQMGLAENQVSFDLIEKYLEEHSEAATWGKGAPSFKDNALFQDYHGLKSF 98
Query: 75 REAVVEYYKKFYD--VDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFVSYVED 132
R A+ + ++ D +++TAGA L + GD +L+P P + + D
Sbjct: 99 RTAMASFMEQIRGGRAKFDPSRIVLTAGATAANELLTFIIANPGDALLLPTPYYPGFDRD 158
Query: 133 AKLAEAKPVRIPLR--EENNFMPDPDEL------LELVTKKTRMIVINYPNNPTGATLDK 184
+ + +P+ NNF P L E + K + ++I P+NP GAT+ +
Sbjct: 159 LRWRTGVNI-VPIHCDSSNNFQITPKALEAAYKEAEAMNMKVKGVLITNPSNPLGATIQR 217
Query: 185 EVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFA-------PENTILANSFSKT 237
+V + I D NI+++SDE Y ++ ++ + + E + S SK
Sbjct: 218 KVLEEILDFVTLKNIHLVSDEIYSGSVFSSSEFISIAEILEARKYKNAERVHIVYSLSKD 277
Query: 238 FAMTGWRLGFVVAPSE-IIKEMIKLHAYIIGNVASFIQVAGVEALRSEE-SWKAVKEMRK 295
+ G+R+G + + ++ ++ ++ ++ + ++S Q L + + +K R+
Sbjct: 278 LGLPGFRVGTIYSYNDKVVTTARRMSSFTL--ISSQTQQLLASMLSDKVFTENYIKTNRE 335
Query: 296 EYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSE------W--LLEKA 347
+R ++++ L GI + + + ++ + K + W L +
Sbjct: 336 RLRKRYTMIIEGLIS-AGIECLKGNAGLFCWMNLSPLLVLENKVTREGELELWNETLHEM 394
Query: 348 RVVVIPGTAFGKMGEGYVRISYATSREKLME-AMDRMEKALSE 389
++ + PG++ G+ R+ +A E+ +E A+ R+ +++
Sbjct: 395 KLNISPGSSCHCSEPGWFRVCFANMSEQTLELALQRIRDFMAK 437
>pir||T47022 hypothetical protein [imported] - Yersinia pestis
>gi|4106610|emb|CAA21365.1| (AL031866) ORF42, len=386 aa
, similarity to an aminotransferase, in P95957
Sulfolobus solfataricus, (401 aa), 33.1% identity in 393
aa overlap, Fasta scores: opt:468, E(): 8.5e-24, in
Q64602 R. norvegicus,(425 aa), 28.6% identity in 409 aa
overlap, Fa>
Length = 386
Score = 69.5 bits (167), Expect = 6e-11
Identities = 80/377 (21%), Positives = 163/377 (43%), Gaps = 21/377 (5%)
Query: 5 RKYFIAERVILIKRSKIRELFERASKMENVISLGIGEPDFDTPKNIKEACKRALDEGWTH 64
+++ + RV + S IRE+ + +IS G P ++ ++ + +
Sbjct: 8 QRHQFSSRVNDLHPSPIREILSVIDR-PGMISFAGGLPAVESFPHMS---LEGMPQPMLQ 63
Query: 65 YTPNAGIQQLREAVVEYYKKFYDVDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDP 124
Y + G +LR+ + + + + E V+I +G+ +G L + ++ G V + P
Sbjct: 64 YGASEGELELRQQIAQNLCE-RGLSCTEEQVLIISGSQQGIDLVAKLFIDEGTPVAVESP 122
Query: 125 AFVSYVEDAKLAEAKPVRIPLREENNFMPDPDELLELVTKKTRMIVINYPNNPTGATLDK 184
+++ ++ + A+ V ++ PD D+L K I NP+G LD
Sbjct: 123 TYLAALQVFRFFGAQFVAY-----DSTQPDIDKLR--TEKPAFAYTIPTFQNPSGHCLDT 175
Query: 185 EVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPM-LKFAPENTILANSFSKTFAMTGW 243
E + +A D + + D+PY +YD + P+ + I SFSK+ +
Sbjct: 176 EQRELLAKTCDDIMLPLFEDDPYHDLVYDPCERKPVCASLQRASWIYQGSFSKSLS-PAL 234
Query: 244 RLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEESWKAVKEMRKEYNERRKL 303
RLG++VA SE+I + +L + + Q ++ LRS + + E+ Y RR
Sbjct: 235 RLGYLVASSELIPYLTRLKQAADLHSSRISQWLVLQQLRSPRHTEHMHELAAYYRTRRDA 294
Query: 304 VLKRLKEMPGIRV--KEPKGAFYVFPSIKDTGMSSEKFSEWLLEKARVVVIPGTAF---G 358
L+ G K+P G + + ++ + + + L + + +PG +F
Sbjct: 295 FEISLQRHFGSLATWKKPAGGLFFWLTLNRCIDTRQLLPKAL--ASNIAFMPGESFLPHS 352
Query: 359 KMGEGYVRISYATSREK 375
G G +R++++ + E+
Sbjct: 353 SEGCGQLRLNFSHATEE 369
>pir||T06253 1-aminocyclopropane-1-carboxylate synthase (EC 4.4.1.14) 2 - garden
pea >gi|2360989|gb|AAD04199.1| (AF016459)
1-aminocyclopropane-1-carboxylate synthase; ACC synthase
[Pisum sativum]
Length = 487
Score = 69.1 bits (166), Expect = 8e-11
Identities = 67/345 (19%), Positives = 149/345 (42%), Gaps = 27/345 (7%)
Query: 70 GIQQLREAVVEYYKKFYD--VDIDVENVIITAGAYEGTYLAFESLLESGDEVLIPDPAFV 127
G+ + R AV ++ + V D E ++++ GA L + G+ +L+P P +
Sbjct: 95 GLPEFRNAVAKFMSRTRGNRVTFDPERIVMSGGATGAHEATAFCLADRGEALLVPTPYYP 154
Query: 128 SYVEDAKLAEA-KPVRIPLREENNFMPDPDELLELVTK------KTRMIVINYPNNPTGA 180
+ D + K V + NNF L E K + + ++I P+NP G
Sbjct: 155 GFDRDLRWRTGVKLVPVICESSNNFKLTKQALEEAYEKAKEDNIRFKGLLITNPSNPLGT 214
Query: 181 TLDKEVAKAIADIAQDYNIYILSDEPYEHFIYDDAKHYPMLKFAPENT---------ILA 231
+D+ + + + I+++SDE Y ++ + + +T +
Sbjct: 215 VMDRNTLRTVITFINEKRIHLISDEIYAATVFSHPSFISIAEIIEHDTDIECDRNLVHIV 274
Query: 232 NSFSKTFAMTGWRLGFVVAPSEIIKEMIKLHAYIIGNVASFIQVAGVEALRSEE-SWKAV 290
S SK G+R+G + + ++ + + + + G V++ Q + L ++ K +
Sbjct: 275 YSLSKDMGFPGFRVGIIYSYNDTVVDCTRKMS-SFGLVSTQTQYLIAKMLSDDDFVEKFL 333
Query: 291 KEMRKEYNERRKLVLKRLKEMPGIRVKEPKGAFYVFPSIKDTGMSSEKFSE---W--LLE 345
E K +R ++ L ++ GI+ + G +V+ ++ ++ SE W ++
Sbjct: 334 PESAKRLAQRYRVFTGGLIKV-GIKCLQSNGGLFVWMDLRGLLKNATFESEIELWRVIIH 392
Query: 346 KARVVVIPGTAFGKMGEGYVRISYATSREKLME-AMDRMEKALSE 389
+ ++ V PG +F G+ R+ YA ++ ++ A+ R+ +++
Sbjct: 393 EVKINVSPGVSFHCSEPGWFRVCYANMDDRDVQIALQRIRSFVTQ 437
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.318 0.136 0.385
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 142032960
Number of Sequences: 2977
Number of extensions: 6129961
Number of successful extensions: 18309
Number of sequences better than 1.0e-10: 335
Number of HSP's better than 0.0 without gapping: 86
Number of HSP's successfully gapped in prelim test: 249
Number of HSP's that attempted gapping in prelim test: 17455
Number of HSP's gapped (non-prelim): 352
length of query: 390
length of database: 189,106,746
effective HSP length: 58
effective length of query: 332
effective length of database: 154,394,500
effective search space: 51258974000
effective search space used: 51258974000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 166 (69.1 bits)