BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1555 (PAB1555) DE:ANION TRANSPORTING ATPASE
         (330 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||D75032 anion transporting atpase PAB1555 - Pyrococcus abyss...   651  0.0
sp|O27555|ARSA_METTH PUTATIVE ARSENICAL PUMP-DRIVING ATPASE (ARS...   190  1e-47
dbj|BAB05514.1| (AP001513) arsenical pump-driving ATPase [Bacill...   174  1e-42
sp|Q58542|ARSA_METJA PUTATIVE ARSENICAL PUMP-DRIVING ATPASE (ARS...   172  4e-42
emb|CAC11579.1| (AL445064) arsenite translocating ATPase (ASNA1)...   157  2e-37
sp|O66674|ARS2_AQUAE PUTATIVE ARSENICAL PUMP-DRIVING ATPASE 2 (A...   156  4e-37
sp|O66908|ARS1_AQUAE PUTATIVE ARSENICAL PUMP-DRIVING ATPASE 1 (A...   147  2e-34
gb|AAF59231.1| (AE003840) CG1598 gene product [Drosophila melano...   143  4e-33
emb|CAB77013.1| (AL159951) putative arsenite-translocating atpas...   138  9e-32
gb|AAA18794.1| (U09867) unknown [Chlorobium vibrioforme] >gi|109...   136  3e-31
gi|4757796 arsA (bacterial) arsenite transporter, ATP-binding, h...   135  6e-31
sp|O54984|ARS1_MOUSE ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRA...   135  8e-31
sp|O43681|ARS1_HUMAN ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRA...   135  8e-31
gi|11525963 arsA (bacterial) arsenite transporter, ATP-binding, ...   135  8e-31
gb|AAC03551.1| (AF047469) arsenite translocating ATPase [Homo sa...   134  1e-30
sp|Q55794|ARSA_SYNY3 PUTATIVE ARSENICAL PUMP-DRIVING ATPASE (ARS...   132  7e-30
dbj|BAB09846.1| (AB005246) arsenite translocating ATPase-like pr...   125  5e-28
gb|AAF76469.1|AC020622_3 (AC020622) Contains similarity to arsen...   125  7e-28
gi|6320103 Ydl100cp [Saccharomyces cerevisiae] >gi|6647438|sp|Q1...   122  6e-27
gb|AAG18929.1| (AE004994) arsenical pump-driving ATPase; ArsA1 [...   119  5e-26
sp|P30632|ARSA_CAEEL PUTATIVE ARSENICAL PUMP-DRIVING ATPASE (ARS...   117  1e-25
gi|10803670 arsA [Halobacterium sp. NRC-1] >gi|6647419|sp|O52027...   115  1e-24
gb|AAD51849.1|AF178758_5 (AF178758) ArsA [Sinorhizobium sp. As4]      107  2e-22
gb|AAD15826.1| (AF061178) arsenical resistance ATPase [Mus muscu...    97  2e-19
pir||H72523 probable arsenite-translocating ATPase APE2165 - Aer...    96  5e-19
gb|AAF89640.1|AF168737_3 (AF168737) ArsA [Klebsiella oxytoca]          82  9e-15
pir||A25937 arsenical pump-driving ATPase (EC 3.6.1.-) - Escheri...    78  1e-13
pdb|1F48|A Chain A, Crystal Structure Of The Escherichia Coli Ar...    78  1e-13
sp|O50593|ARSA_ACIMU ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRA...    78  2e-13
sp|P52145|ARA2_ECOLI ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRA...    76  4e-13
sp|P08690|ARA1_ECOLI ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRA...    76  4e-13
pir||T36563 probable ion-transporting ATPase - Streptomyces coel...    71  2e-11
pir||A70791 probable anion transporting ATPase - Mycobacterium t...    70  4e-11

>pir||D75032 anion transporting atpase PAB1555 - Pyrococcus abyssi  (strain
           Orsay) >gi|5458666|emb|CAB50153.1| (AJ248287) ANION
           TRANSPORTING ATPASE [Pyrococcus abyssi]
           Length = 330
           
 Score =  651 bits (1662), Expect = 0.0
 Identities = 330/330 (100%), Positives = 330/330 (100%)

Query: 1   MREFLTPKEGFRVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEK 60
           MREFLTPKEGFRVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEK
Sbjct: 1   MREFLTPKEGFRVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEK 60

Query: 61  LSDKPREIIDNLYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIE 120
           LSDKPREIIDNLYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIE
Sbjct: 61  LSDKPREIIDNLYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIE 120

Query: 121 EYATLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRR 180
           EYATLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRR
Sbjct: 121 EYATLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRR 180

Query: 181 AITKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMN 240
           AITKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMN
Sbjct: 181 AITKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMN 240

Query: 241 PEFLPLYETKRAYESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEKVLSEVKREFP 300
           PEFLPLYETKRAYESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEKVLSEVKREFP
Sbjct: 241 PEFLPLYETKRAYESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEKVLSEVKREFP 300

Query: 301 GVEIVEIPMFQEEPRGIEWLSKVGEMIVGR 330
           GVEIVEIPMFQEEPRGIEWLSKVGEMIVGR
Sbjct: 301 GVEIVEIPMFQEEPRGIEWLSKVGEMIVGR 330


>sp|O27555|ARSA_METTH PUTATIVE ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING
           ATPASE) (ARSENICAL RESISTANCE ATPASE)
           >gi|7428325|pir||F69068 probable arsenical pump-driving
           ATPase (EC 3.6.1.-) - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622629|gb|AAB85986.1| (AE000911) arsenical
           pump-driving ATPase [Methanobacterium
           thermoautotrophicum]
           Length = 324
           
 Score =  190 bits (479), Expect = 1e-47
 Identities = 103/316 (32%), Positives = 187/316 (58%), Gaps = 13/316 (4%)

Query: 14  IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREIIDNLY 73
           +F+ GKGGVGKTT SA+ ++ +A++G +TL++S DPAH+L D    ++   P +I +NLY
Sbjct: 17  VFIGGKGGVGKTTISAATALWMARSGKKTLVISTDPAHSLSDSLEREIGHTPTKITENLY 76

Query: 74  ASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAIREILV 133
           A E+D E  ++ Y   L++    M   + +  L+   ++   SPGI+E A  +     + 
Sbjct: 77  AVEIDPEVAMEEYQAKLQEQAA-MNPGMGLDMLQDQMDMASMSPGIDEAAAFDQFLRYMT 135

Query: 134 KGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQKFVI 193
             DE+D+++FDT PTG TLR+L+ P I   W  K+I IR++I    +A   I        
Sbjct: 136 T-DEYDIVIFDTAPTGHTLRLLSFPEIMDSWVGKMIKIRRQIGSMAKAFKNI-----LPF 189

Query: 194 DGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYETKRAY 253
            G+E      EEED  +++++A + +I    +V+++P +TS   V+ PE + +YE++RA 
Sbjct: 190 MGDE------EEEDRALQDMEATKKQINAAREVMSDPERTSFKMVVIPEEMSIYESERAM 243

Query: 254 ESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEKVLSEVKREFPGVEIVEIPMFQEE 313
           ++L+K+ I  + V++N+V+  + +      + + Q++ L +++ +F    + E+P+ ++E
Sbjct: 244 KALEKYSIHADGVIVNQVLPEESDCEFCNARRKLQQERLKQIREKFSDKVVAEVPLLKKE 303

Query: 314 PRGIEWLSKVGEMIVG 329
            +GIE L K+ E + G
Sbjct: 304 AKGIETLEKIAEQLYG 319


>dbj|BAB05514.1| (AP001513) arsenical pump-driving ATPase [Bacillus halodurans]
           Length = 313
           
 Score =  174 bits (436), Expect = 1e-42
 Identities = 97/309 (31%), Positives = 173/309 (55%), Gaps = 17/309 (5%)

Query: 13  VIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREIIDNL 72
           + F+ GKGGVGK+TS+AS +   A+ G +TL++S DPAHNLGD+F  ++  K ++I DNL
Sbjct: 9   IYFIGGKGGVGKSTSAASFAWRCAERGEKTLLISTDPAHNLGDLFHTEIGAKHKKITDNL 68

Query: 73  YASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAIREIL 132
           +A+E+D E   + Y++ ++ NL+ M +   +  + +  +    +PG +E A   AI  I+
Sbjct: 69  FATEIDPEQETRRYIQSVKDNLRGMVKSTMLDEVNRQIDAAAATPGADEAAMFNAISSIV 128

Query: 133 V-KGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQKF 191
           + +   +D +VFDT PTG T+R+L LP +  VW + ++  RKKI E              
Sbjct: 129 LDEQGTYDKLVFDTAPTGHTIRLLTLPEMMGVWIDGMVKKRKKINE---------NYSNL 179

Query: 192 VIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYETKR 251
           + DGE +       +D +   L+  ++    V +VL +P KT  + V+ PE LP+ ET++
Sbjct: 180 LNDGEPV-------DDPIYDTLQQRKERFAAVRNVLLDPKKTGFMFVLIPERLPILETEK 232

Query: 252 AYESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEKVLSEVKREFPGVEIVEIPMFQ 311
           A + L K  +    +++NK++    +   +  + + +++ L ++   F    ++ +P+F 
Sbjct: 233 AVKLLAKHDLHVETLIINKILPDVADGQFLEKRRQIEQRYLQQIHNTFRKQTLLRVPLFP 292

Query: 312 EEPRGIEWL 320
           E+   IE L
Sbjct: 293 EDIGSIEAL 301


>sp|Q58542|ARSA_METJA PUTATIVE ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING
           ATPASE) (ARSENICAL RESISTANCE ATPASE)
           >gi|2127768|pir||E64442 probable arsenical pump-driving
           ATPase (EC 3.6.1.-) - Methanococcus jannaschii
           >gi|1591774|gb|AAB99142.1| (U67556) arsenical
           pump-driving ATPase (arsA) [Methanococcus jannaschii]
           Length = 349
           
 Score =  172 bits (432), Expect = 4e-42
 Identities = 106/327 (32%), Positives = 186/327 (56%), Gaps = 14/327 (4%)

Query: 5   LTPKEGFRVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDK 64
           L  K+G + I   GKGGVGKTT SA+  V LA+ G + +IVS DPAH+L D+F ++   +
Sbjct: 20  LEKKDGTKYIMFGGKGGVGKTTMSAATGVYLAEKGLKVVIVSTDPAHSLRDIFEQEFGHE 79

Query: 65  PREI--IDNLYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIEEY 122
           P ++   DNLY  E+D +  ++ Y E L+  ++    +L  + LE   E+   SPG +E 
Sbjct: 80  PTKVKGYDNLYVVEIDPQKAMEEYKEKLKAQIEEN-PFLGEM-LEDQLEMAALSPGTDES 137

Query: 123 ATLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAI 182
           A  +   + +   +E+DV++FDT PTG TLR L +P +   +  KLI +RK++    + +
Sbjct: 138 AAFDVFLKYM-DSNEFDVVIFDTAPTGHTLRFLGMPEVMDKYMTKLIKLRKQMSGFMKMM 196

Query: 183 TKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPE 242
            K+     F    E+I      + D ++ EL+  ++ I    ++L++P +T+   V+ PE
Sbjct: 197 KKLL---PFGGKDEDI------DYDKMLEELEKMKERIVRARNILSDPERTAFRLVVIPE 247

Query: 243 FLPLYETKRAYESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEKVLSEVKREFPGV 302
            + + E++RA ++L+K+ IP + V++N++I    +    R + E Q K L  +K +F   
Sbjct: 248 EMSILESERAMKALQKYGIPIDAVIVNQLIPEDVQCDFCRARRELQLKRLEMIKEKFGDK 307

Query: 303 EIVEIPMFQEEPRGIEWLSKVGEMIVG 329
            I  +P+ + E +GIE L ++ +++ G
Sbjct: 308 VIAYVPLLRTEAKGIETLKQIAKILYG 334


>emb|CAC11579.1| (AL445064) arsenite translocating ATPase (ASNA1) related protein
           [Thermoplasma acidophilum]
           Length = 387
           
 Score =  157 bits (393), Expect = 2e-37
 Identities = 100/321 (31%), Positives = 175/321 (54%), Gaps = 23/321 (7%)

Query: 12  RVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREIIDN 71
           R++   GKGGVGKT+ +A+    L+  G++TLI+S DPAH+LGD F  ++    +++ DN
Sbjct: 4   RILLYTGKGGVGKTSIAAATGALLSSKGHKTLIISTDPAHSLGDAFGMEIGHSIKQLADN 63

Query: 72  LYASELDMEGMIKGYLEHLEKNLKNMY--RYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129
           LY  E+ +   I  +   L+  L++++  + L  ++ ++    +   PG EE + L  +R
Sbjct: 64  LYGQEVSVVQSINEHWGELKDYLRSLFLSQGLDPVSADE----IATLPGFEEASELLYLR 119

Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189
                 +E+D I+ D+ PTG  L++L+ P +   + +KL  I +K     R + K     
Sbjct: 120 NYYY-DEEYDTIIMDSAPTGAALQLLSFPEVMTWYMDKLFPISRKTARVARPLLK----- 173

Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249
            FV    +I LP    EDAV   +     ++  +  +LTN + TS+  V NP+ +   ET
Sbjct: 174 PFV----DIPLP----EDAVFENIDLLYRQLTDIRKILTNNDVTSIRLVTNPDNMSYSET 225

Query: 250 KRAYESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEK-VLSEVKREFPGVEIVEIP 308
           KRAY  L  +  P + V++NK+  L  E  +   K+   +K +++E++  F  ++I +  
Sbjct: 226 KRAYTYLLLYGYPVDAVIINKI--LSDETGDFFEKMRGSQKDIITEMENSFVDIKIFKAR 283

Query: 309 MFQEEPRGIEWLSKVGEMIVG 329
           + QEEP GI+ L ++G++I G
Sbjct: 284 LLQEEPIGIKKLIELGKLIYG 304


>sp|O66674|ARS2_AQUAE PUTATIVE ARSENICAL PUMP-DRIVING ATPASE 2 (ARSENITE-TRANSLOCATING
           ATPASE 2) (ARSENICAL RESISTANCE ATPASE 2)
           >gi|7428326|pir||F70330 probable arsenical pump-driving
           ATPase (EC 3.6.1.-) - Aquifex aeolicus
           >gi|2983014|gb|AAC06625.1| (AE000684) anion transporting
           ATPase [Aquifex aeolicus]
           Length = 299
           
 Score =  156 bits (390), Expect = 4e-37
 Identities = 99/317 (31%), Positives = 168/317 (52%), Gaps = 23/317 (7%)

Query: 12  RVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREIIDN 71
           RV F  GKGGVGKTT+S++ +V L++ G + L++S DPAH+L DVF  +L  + + + +N
Sbjct: 2   RVFFFGGKGGVGKTTASSAFAVKLSEQGKKVLLLSTDPAHSLSDVFNTELQGETK-LSEN 60

Query: 72  LYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAI-RE 130
           L   E+D+   +K Y   + K  +   R  T+  LE     L  SPGIE+    EA+ +E
Sbjct: 61  LTVKEIDLNEELKEYRSRVFKLAEATLRKETLRELEGIIHSLEESPGIEDVVIFEALSKE 120

Query: 131 ILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQK 190
           ++ + +E+D IV DT PTG TL +L   R    + E+++ +++K+ E +           
Sbjct: 121 VVYRENEYDYIVVDTAPTGHTLGLLKTVRNLGNFLEEIVKLKEKVYELK----------- 169

Query: 191 FVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYETK 250
                   KL  +   +  +  LK  ++  K   +++   +K+   AV+ PE LP  ETK
Sbjct: 170 --------KLSGKSVHEEALEYLKERKERFKKFSEIIY--DKSYFFAVLTPEKLPFEETK 219

Query: 251 RAYESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEKVLSEVKREFPGVEIVEIPMF 310
           R   SLK + I    +++NKV+    +   ++ + E ++K L E++  F  +E + IP  
Sbjct: 220 RLVNSLKHYGIRVKALIINKVLPENPQDEFLKARKEVEKKFLKEIENYFMDIEKISIPYQ 279

Query: 311 QEEPRGIEWLSKVGEMI 327
           +EE  G E L +  + +
Sbjct: 280 KEEVVGYEKLKEFSKFL 296


>sp|O66908|ARS1_AQUAE PUTATIVE ARSENICAL PUMP-DRIVING ATPASE 1 (ARSENITE-TRANSLOCATING
           ATPASE 1) (ARSENICAL RESISTANCE ATPASE 1)
           >gi|7451716|pir||H70359 anion transporting ATPase -
           Aquifex aeolicus >gi|2983270|gb|AAC06864.1| (AE000701)
           anion transporting ATPase [Aquifex aeolicus]
           Length = 396
           
 Score =  147 bits (367), Expect = 2e-34
 Identities = 103/333 (30%), Positives = 177/333 (52%), Gaps = 36/333 (10%)

Query: 12  RVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVF------MEKLSDKP 65
           R+I   GKGGVGKTT SA+    L++ G + ++VSLDPAH+L D F        K    P
Sbjct: 2   RIILFSGKGGVGKTTISAATGYKLSQLGKKVIVVSLDPAHSLADSFDVPEEERRKAKGLP 61

Query: 66  REIIDNLYASELDMEGMIKGYLEHLEKNLKNMYRYLTVI-----NLEKYFEVLRYSPGIE 120
            +I +NL   E+D++       E +E+    +YR++ ++       E   + L   PG+E
Sbjct: 62  IKINENLEIQEIDIQ-------EEIERYWGEVYRFIELLFHTTGLHEILADELAILPGME 114

Query: 121 EYATLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRR 180
           E  +L  + +   +G+  DV++ D PPTG ++R +++P + + W        KKI +  R
Sbjct: 115 EITSLLYVNKYYREGNH-DVLILDLPPTGESIRFVSMPTV-MKW------YMKKIFKTER 166

Query: 181 AITKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMN 240
            I K+         G    +P  +EE    + L+ + + +K V+++L NP+ TS+  V N
Sbjct: 167 LIMKVARPTV----GRMTDVPLPDEE--YFKALETFYERLKGVDEILINPDITSIRIVSN 220

Query: 241 PEFLPLYETKRAYESLKKFKIPFNMVVMNKVIK---LKREIPEIRVK-LEAQEKVLSEVK 296
           PE + L E++RA+     F +  + V++NKVI    +++E      K L  Q+K + E++
Sbjct: 221 PEKMVLKESQRAFLYFLLFGVNVDAVIVNKVIPEEVIQQENCSFLEKWLNIQKKYVKEIE 280

Query: 297 REFPGVEIVEIPMFQEEPRGIEWLSKVGEMIVG 329
             F  V + ++P+ +EE  G+E L K+ ++I G
Sbjct: 281 SYFSPVPVFKVPLLEEEVVGLERLEKLAQLIYG 313


>gb|AAF59231.1| (AE003840) CG1598 gene product [Drosophila melanogaster]
           Length = 336
           
 Score =  143 bits (356), Expect = 4e-33
 Identities = 96/329 (29%), Positives = 165/329 (49%), Gaps = 23/329 (6%)

Query: 5   LTPKEGFRVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDK 64
           L  ++  + IFV GKGGVGKTT S+S++V L+K     LI+S DPAHN+ D F +K +  
Sbjct: 15  LVEQDSLKWIFVGGKGGVGKTTCSSSLAVQLSKVRESVLIISTDPAHNISDAFDQKFTKV 74

Query: 65  PREI--IDNLYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIEEY 122
           P ++   DNL+A E+D    +    E          R    ++     E++   PGI+E 
Sbjct: 75  PTKVNGFDNLFAMEIDPNAGLNELPEEYFDGENEALR----VSKGVMQEMINALPGIDEA 130

Query: 123 ATLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAI 182
            +   + + LVKG  + V+VFDT PTG TLR++A P++      KL+ ++ K+       
Sbjct: 131 MSYAEVMK-LVKGMNFSVVVFDTAPTGHTLRLIAFPQVVEKGLGKLLRLKMKVAPLLSQF 189

Query: 183 TKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPE 242
             + G      D    KL      D ++R +    ++ K       NP++T+ + V   E
Sbjct: 190 VSMLGMADVNADTLSQKL------DDMLRVITQVNEQFK-------NPDQTTFVCVCIAE 236

Query: 243 FLPLYETKRAYESLKKFKIPFNMVVMNKVIKLKREIPEIRV---KLEAQEKVLSEVKREF 299
           F  LYET+R  + L K  I  + +++N+++ L+       +   + + QEK L ++   +
Sbjct: 237 FFSLYETERLVQELTKCGIDVHNIIVNQLLFLQNSHDSCSMCASRFKIQEKYLDQIADLY 296

Query: 300 PGVEIVEIPMFQEEPRGIEWLSKVGEMIV 328
               + ++P+ ++E RG E +    E ++
Sbjct: 297 EDFHVTKLPLLEKEVRGPESIRSFSENLM 325


>emb|CAB77013.1| (AL159951) putative arsenite-translocating atpase
           [Schizosaccharomyces pombe]
           Length = 329
           
 Score =  138 bits (344), Expect = 9e-32
 Identities = 100/331 (30%), Positives = 161/331 (48%), Gaps = 28/331 (8%)

Query: 3   EFLTPKEGFRVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLS 62
           E L  +   + IFV GKGGVGKTT+S S+++ ++K     L++S DPAHNL D F  K  
Sbjct: 11  ENLLEQTSLKWIFVGGKGGVGKTTTSCSLAIQMSKVRSSVLLISTDPAHNLSDAFGTKFG 70

Query: 63  DKPREI--IDNLYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIE 120
              R++   DNL A E+D    I+   E  ++  +N    L+ +  +  F +    PGI+
Sbjct: 71  KDARKVPGFDNLSAMEIDPNLSIQEMTEQADQ--QNPNNPLSGMMQDLAFTI----PGID 124

Query: 121 EYATLEAIREIL--VKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILER 178
           E     A  EIL  +K  E+D ++FDT PTG TLR L  P +      KL  +  +    
Sbjct: 125 EAL---AFAEILKQIKSMEFDCVIFDTAPTGHTLRFLNFPTVLEKALGKLGGLSSRFGPM 181

Query: 179 RRAITKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAV 238
              +  I G                  E  +  ++++ R  I  V     NP+ T+ + V
Sbjct: 182 INQMGSIMG--------------VNANEQDLFGKMESMRANISEVNKQFKNPDLTTFVCV 227

Query: 239 MNPEFLPLYETKRAYESLKKFKIPFNMVVMNK-VIKLKREIPEIRVKLEAQEKVLSEVKR 297
              EFL LYET+R  + L  ++I  + +V+N+ ++      P+   + + Q+K L++++ 
Sbjct: 228 CISEFLSLYETERMIQELTSYEIDTHNIVVNQLLLDPNTTCPQCMARRKMQQKYLAQIEE 287

Query: 298 EFPGVEIVEIPMFQEEPRGIEWLSKVGEMIV 328
            +    +V++P    E RG E L    EM+V
Sbjct: 288 LYEDFHVVKVPQVPAEVRGTEALKSFSEMLV 318


>gb|AAA18794.1| (U09867) unknown [Chlorobium vibrioforme] >gi|1098330|prf||2115394E
           ORF Z [Chlorobium vibrioforme]
           Length = 405
           
 Score =  136 bits (340), Expect = 3e-31
 Identities = 99/325 (30%), Positives = 173/325 (52%), Gaps = 27/325 (8%)

Query: 12  RVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREIIDN 71
           R++   GKGGVGKT+ SA+ +V L++ G+RTL++S DPAH+L D F  +L  +P +I +N
Sbjct: 2   RILTFTGKGGVGKTSVSAATAVRLSEMGHRTLVLSTDPAHSLSDSFNLQLGAEPTKIKEN 61

Query: 72  LYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEK-----YFEVLRYSPGIEEYATLE 126
           L+A E      +  Y++ L++N  ++ +Y T + + +       + +   PG+EE  +L 
Sbjct: 62  LHAIE------VNPYVD-LKENWHSVQKYYTRVFMAQGVSGVMADEMTILPGMEELFSLL 114

Query: 127 AIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILER--RRAITK 184
            I+     G  +D +V DT PTG TLR+L+LP  +L W  K +    K + R   + ++K
Sbjct: 115 RIKRYKSTG-LYDALVLDTAPTGETLRLLSLPD-TLSWGMKAVKNVNKYIVRPLSKPLSK 172

Query: 185 IQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFL 244
           +  +  + I  E+      E  D V        DE++ + D+LT+  K++V  VMN E +
Sbjct: 173 MSDKIAYYIPPED----AIESVDQVF-------DELEDIRDILTDNVKSTVRLVMNAEKM 221

Query: 245 PLYETKRAYESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEKVLSEVKREFPGVEI 304
            + ET RA   L  +    +MV++NK++  +     +      Q+K L E++  F  + +
Sbjct: 222 SIKETMRALTYLNLYGFKVDMVLVNKLLDAQENSGYLEKWKGIQQKYLGEIEEGFSPLPV 281

Query: 305 VEIPMFQEEPRGIEWLSKVGEMIVG 329
            ++ M+ +E  G++ L      I G
Sbjct: 282 KKLKMYDQEIVGVKSLEVFAHDIYG 306


>gi|4757796 arsA (bacterial) arsenite transporter, ATP-binding, homolog 1 [Homo
           sapiens] >gi|1616741|gb|AAC50731.1| (U60276) hASNA-I
           [Homo sapiens]
           Length = 332
           
 Score =  135 bits (337), Expect = 6e-31
 Identities = 103/323 (31%), Positives = 166/323 (50%), Gaps = 31/323 (9%)

Query: 14  IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--IDN 71
           IFV GKGGVGKTT S S++V L+K     LI+S DPAHN+ D F +K S  P ++   DN
Sbjct: 24  IFVGGKGGVGKTTCSCSLAVQLSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDN 83

Query: 72  LYASELDMEGMIKGYLEHL--EKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129
           L+A E+D    +    +    E N+ +M + +         E +   PGI+E  +   + 
Sbjct: 84  LFAMEIDPSLGVADVPDEFFEEDNMLSMGKKMMQ-------EAMSAFPGIDEAMSYAEVM 136

Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189
             LVKG  + V+VFDT PTG TLR+L  P I      +L+ I+ +I      +  + G  
Sbjct: 137 R-LVKGMNFSVVVFDTAPTGHTLRLLNFPTIVERGLGRLMQIKNQISPFISQMCNMLG-- 193

Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249
             + D    +L ++ EE   +         I+ V +   +P +T+ I V   EFL LYET
Sbjct: 194 --LGDMNADQLASKLEETLPV---------IRSVSEQFKDPEQTTFICVCIAEFLSLYET 242

Query: 250 KRAYESLKKFKIPFNMVVMNKVIKLKREIP----EIRVKLEAQEKVLSEVKREFPGVEIV 305
           +R  + L K KI  + +++N+++    E P    E R K++A  K L +++  +    IV
Sbjct: 243 ERLIQELAKCKIDTHNIIVNQLVFPDPEKPCKMCEARHKIQA--KYLDQMEDLYEDFHIV 300

Query: 306 EIPMFQEEPRGIEWLSKVGEMIV 328
           ++P+   E RG + ++    +++
Sbjct: 301 KLPLLPHEVRGADKVNTFSALLL 323


>sp|O54984|ARS1_MOUSE ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING ATPASE)
           (ARSENICAL RESISTANCE ATPASE) (ARSA)
           >gi|2745900|gb|AAB94772.1| (AF039405)
           arsenite-translocating ATPase [Mus musculus]
           Length = 350
           
 Score =  135 bits (336), Expect = 8e-31
 Identities = 103/323 (31%), Positives = 166/323 (50%), Gaps = 31/323 (9%)

Query: 14  IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--IDN 71
           IFV GKGGVGKTT S S++V L+K     LI+S DPAHN+ D F +K S  P ++   DN
Sbjct: 40  IFVGGKGGVGKTTCSCSLAVQLSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDN 99

Query: 72  LYASELDMEGMIKGYLEHL--EKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129
           L+A E+D    +    +    E N+ +M + +         E +   PGI+E  +   + 
Sbjct: 100 LFAMEIDPSLGVAELPDEFFEEDNMLSMGKKMMQ-------EAMSAFPGIDEAMSYAEVM 152

Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189
             LVKG  + V+VFDT PTG TLR+L  P I      +L+ I+ +I      +  + G  
Sbjct: 153 R-LVKGMNFSVVVFDTAPTGHTLRLLNFPTIVERGLGRLMQIKNQISPFISQMCNMLG-- 209

Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249
             + D    +L ++ EE   +         I+ V +   +P +T+ I V   EFL LYET
Sbjct: 210 --LGDMNADQLASKLEETLPV---------IRSVSEQFKDPEQTTFICVCIAEFLSLYET 258

Query: 250 KRAYESLKKFKIPFNMVVMNKVIKLKREIP----EIRVKLEAQEKVLSEVKREFPGVEIV 305
           +R  + L K KI  + +++N+++    E P    E R K++A  K L +++  +    IV
Sbjct: 259 ERLIQELAKCKIDTHNIIVNQLVFPDPEKPCKMCEARHKIQA--KYLDQMEDLYEDFHIV 316

Query: 306 EIPMFQEEPRGIEWLSKVGEMIV 328
           ++P+   E RG + ++    +++
Sbjct: 317 KLPLLPHEVRGADKVNTFSALLL 339


>sp|O43681|ARS1_HUMAN ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING ATPASE)
           (ARSENICAL RESISTANCE ATPASE) (ARSA) (ASNA-I)
           Length = 348
           
 Score =  135 bits (336), Expect = 8e-31
 Identities = 103/323 (31%), Positives = 166/323 (50%), Gaps = 31/323 (9%)

Query: 14  IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--IDN 71
           IFV GKGGVGKTT S S++V L+K     LI+S DPAHN+ D F +K S  P ++   DN
Sbjct: 40  IFVGGKGGVGKTTCSCSLAVQLSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDN 99

Query: 72  LYASELDMEGMIKGYLEHL--EKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129
           L+A E+D    +    +    E N+ +M + +         E +   PGI+E  +   + 
Sbjct: 100 LFAMEIDPSLGVAELPDEFFEEDNMLSMGKKMMQ-------EAMSAFPGIDEAMSYAEVM 152

Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189
             LVKG  + V+VFDT PTG TLR+L  P I      +L+ I+ +I      +  + G  
Sbjct: 153 R-LVKGMNFSVVVFDTAPTGHTLRLLNFPTIVERGLGRLMQIKNQISPFISQMCNMLG-- 209

Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249
             + D    +L ++ EE   +         I+ V +   +P +T+ I V   EFL LYET
Sbjct: 210 --LGDMNADQLASKLEETLPV---------IRSVSEQFKDPEQTTFICVCIAEFLSLYET 258

Query: 250 KRAYESLKKFKIPFNMVVMNKVIKLKREIP----EIRVKLEAQEKVLSEVKREFPGVEIV 305
           +R  + L K KI  + +++N+++    E P    E R K++A  K L +++  +    IV
Sbjct: 259 ERLIQELAKCKIDTHNIIVNQLVFPDPEKPCKMCEARHKIQA--KYLDQMEDLYEDFHIV 316

Query: 306 EIPMFQEEPRGIEWLSKVGEMIV 328
           ++P+   E RG + ++    +++
Sbjct: 317 KLPLLPHEVRGADKVNTFSALLL 339


>gi|11525963 arsA (bacterial) arsenite transporter, ATP-binding, homolog 1 [Homo
           sapiens]
           Length = 331
           
 Score =  135 bits (336), Expect = 8e-31
 Identities = 103/323 (31%), Positives = 166/323 (50%), Gaps = 31/323 (9%)

Query: 14  IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--IDN 71
           IFV GKGGVGKTT S S++V L+K     LI+S DPAHN+ D F +K S  P ++   DN
Sbjct: 23  IFVGGKGGVGKTTCSCSLAVQLSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDN 82

Query: 72  LYASELDMEGMIKGYLEHL--EKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129
           L+A E+D    +    +    E N+ +M + +         E +   PGI+E  +   + 
Sbjct: 83  LFAMEIDPSLGVAELPDEFFEEDNMLSMGKKMMQ-------EAMSAFPGIDEAMSYAEVM 135

Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189
             LVKG  + V+VFDT PTG TLR+L  P I      +L+ I+ +I      +  + G  
Sbjct: 136 R-LVKGMNFSVVVFDTAPTGHTLRLLNFPTIVERGLGRLMQIKNQISPFISQMCNMLG-- 192

Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249
             + D    +L ++ EE   +         I+ V +   +P +T+ I V   EFL LYET
Sbjct: 193 --LGDMNADQLASKLEETLPV---------IRSVSEQFKDPEQTTFICVCIAEFLSLYET 241

Query: 250 KRAYESLKKFKIPFNMVVMNKVIKLKREIP----EIRVKLEAQEKVLSEVKREFPGVEIV 305
           +R  + L K KI  + +++N+++    E P    E R K++A  K L +++  +    IV
Sbjct: 242 ERLIQELAKCKIDTHNIIVNQLVFPDPEKPCKMCEARHKIQA--KYLDQMEDLYEDFHIV 299

Query: 306 EIPMFQEEPRGIEWLSKVGEMIV 328
           ++P+   E RG + ++    +++
Sbjct: 300 KLPLLPHEVRGADKVNTFSALLL 322


>gb|AAC03551.1| (AF047469) arsenite translocating ATPase [Homo sapiens]
           Length = 348
           
 Score =  134 bits (335), Expect = 1e-30
 Identities = 103/323 (31%), Positives = 166/323 (50%), Gaps = 31/323 (9%)

Query: 14  IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--IDN 71
           IFV GKGGVGKTT S S++V L+K     LI+S DPAHN+ D F +K S  P ++   DN
Sbjct: 40  IFVGGKGGVGKTTCSCSLAVQLSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDN 99

Query: 72  LYASELDMEGMIKGYLEHL--EKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129
           L+A E+D    +    +    E N+ +M + +         E +   PGI+E  +   + 
Sbjct: 100 LFAMEIDPSLGVAELPDEFFEEDNMLSMGKKMMQ-------EAMSAFPGIDEAMSYAEVM 152

Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189
             LVKG  + V+VFDT PTG TLR+L  P I      +L+ I+ +I      +  + G  
Sbjct: 153 R-LVKGMNFSVVVFDTAPTGHTLRLLNFPTIVERGLGRLMQIKNQISPFISQMFNMLG-- 209

Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249
             + D    +L ++ EE   +         I+ V +   +P +T+ I V   EFL LYET
Sbjct: 210 --LGDMNADQLASKLEETLPV---------IRSVSEQFKDPEQTTFICVCIAEFLSLYET 258

Query: 250 KRAYESLKKFKIPFNMVVMNKVIKLKREIP----EIRVKLEAQEKVLSEVKREFPGVEIV 305
           +R  + L K KI  + +++N+++    E P    E R K++A  K L +++  +    IV
Sbjct: 259 ERLIQELAKCKIDTHNIIVNQLVFPDPEKPCKMCEARHKIQA--KYLDQMEDLYEDFHIV 316

Query: 306 EIPMFQEEPRGIEWLSKVGEMIV 328
           ++P+   E RG + ++    +++
Sbjct: 317 KLPLLPHEVRGADKVNTFSALLL 339


>sp|Q55794|ARSA_SYNY3 PUTATIVE ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING
           ATPASE) (ARSENICAL RESISTANCE ATPASE)
           >gi|7451715|pir||S76602 hypothetical protein -
           Synechocystis sp. (strain PCC 6803)
           >gi|1001709|dbj|BAA10546.1| (D64004) hypothetical
           protein [Synechocystis sp.]
           Length = 396
           
 Score =  132 bits (328), Expect = 7e-30
 Identities = 98/322 (30%), Positives = 166/322 (51%), Gaps = 24/322 (7%)

Query: 12  RVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREIIDN 71
           RVI + GKGGVGKT+ +A+  +  A+ G++TL++S DPAH+L D F  +L  +PR + +N
Sbjct: 2   RVILMTGKGGVGKTSVAAATGLRCAELGHKTLVLSTDPAHSLADSFDLELGHEPRLVKEN 61

Query: 72  LYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEK-----YFEVLRYSPGIEEYATLE 126
           L+ +ELD        L  LE N   + RY+T +   +       E L   PG++E   L 
Sbjct: 62  LWGAELDA-------LMELEGNWGAVKRYITQVLQARGLDGVQAEELAILPGMDEIFGLV 114

Query: 127 AIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQ 186
            ++    + D +DV++ D+ PTG  LR+L+LP +   +  +      K L+      +  
Sbjct: 115 RMKRHYDEAD-YDVLIIDSAPTGTALRLLSLPEVGGWYMRRFY----KPLQGMSVALRPL 169

Query: 187 GEQKF-VIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLP 245
            E  F  I G    LP +E  DA       + ++I+ +E VLT+  +TSV  V NPE + 
Sbjct: 170 VEPLFRPIAG--FSLPDKEVMDAPYE----FYEQIEALEKVLTDNTQTSVRLVTNPEKMV 223

Query: 246 LYETKRAYESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEKVLSEVKREFPGVEIV 305
           L E+ RA+  L  + +  ++V+ N+++    + P  +     Q+    E+   F  + + 
Sbjct: 224 LKESLRAHAYLSLYNVSTDLVIANRILPETIDDPFFQRWKSNQQVYKQEIYDNFHPLPVK 283

Query: 306 EIPMFQEEPRGIEWLSKVGEMI 327
           E P+F EE  G+  L ++ + +
Sbjct: 284 EAPLFSEEMCGLAALERLKDTL 305


>dbj|BAB09846.1| (AB005246) arsenite translocating ATPase-like protein [Arabidopsis
           thaliana]
           Length = 417
           
 Score =  125 bits (312), Expect = 5e-28
 Identities = 94/330 (28%), Positives = 176/330 (52%), Gaps = 36/330 (10%)

Query: 18  GKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSD---KPREIIDN-LY 73
           GKGGVGKT+ +AS++V  A  G+ T++VS DPAH+L D F + LS    KP + +D+ L 
Sbjct: 102 GKGGVGKTSCAASLAVKFASHGHPTIVVSTDPAHSLSDSFSQDLSGGVLKPVQGVDSPLL 161

Query: 74  ASELDMEGMIKGYLEHL--EKNLKNMYRYLTV---------INLEKYFEVLRYSPGIEEY 122
           A E+  E ++K  ++    +K++KNM   + +         +NLE        SPGI+E 
Sbjct: 162 ALEITPE-IMKDEIKRQTGDKSVKNMMDSMGLGMFAGELGDLNLEDMLNAA--SPGIDEI 218

Query: 123 ATLEAIREILVKGD--EWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRR 180
           A +  + + +   +   +  IVFDT PTG TLR+L+LP        K+  ++KKI     
Sbjct: 219 AAISKVLQFMEAPEYSRFTRIVFDTAPTGHTLRLLSLPDFYDSSISKITKLKKKITAAAS 278

Query: 181 AITKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMN 240
           A   + G+++     ++ +LP          EL   ++ ++ V +V  + + T  + V  
Sbjct: 279 AFKLVFGKKEI----QQKELP---------NELDQLKERMEKVRNVFRDVDTTEFVIVTI 325

Query: 241 PEFLPLYETKRAYESLKKFKIPFNMVVMNKVI-KLKREIPEIRVKLEAQEKVLSEVKR-- 297
           P  + + E+ R + SL+K  +P + +++N+++ + + +     ++ + Q +VL  ++   
Sbjct: 326 PTVMAINESSRLHASLRKENVPVHRLIVNQLLPQSESDCKFCSIRRKEQTRVLGLIQNDT 385

Query: 298 EFPGVEIVEIPMFQEEPRGIEWLSKVGEMI 327
           E  G+++++ P+   E RG+  L  +G++I
Sbjct: 386 ELSGLKLIQSPLLDAEIRGVPALKFMGDLI 415


>gb|AAF76469.1|AC020622_3 (AC020622) Contains similarity to arsenite translocating ATPase
           from Homo sapiens gb|AF047469 and contains a 4Fe-4S iron
           sulfur cluster binding protein PF|00142 domain.  EST
           gb|N37510 comes from this gene. [Arabidopsis thaliana]
           Length = 345
           
 Score =  125 bits (311), Expect = 7e-28
 Identities = 95/325 (29%), Positives = 158/325 (48%), Gaps = 54/325 (16%)

Query: 8   KEGFRVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPRE 67
           +E  + +FV GKGGVGKTT S+ +++ LA      LI+S DPAHNL D F ++ +  P  
Sbjct: 16  QESLKWVFVGGKGGVGKTTCSSILAICLASVRSSVLIISTDPAHNLSDAFQQRFTKSPTL 75

Query: 68  I--IDNLYASEL-------DMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPG 118
           +    NL+A E+       DM G     ++ L  +L N                    PG
Sbjct: 76  VQGFSNLFAMEVDPTVETDDMAG--TDGMDGLFSDLANAI------------------PG 115

Query: 119 IEEYATLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILER 178
           I+E  +   + + LV+  ++  IVFDT PTG TLR+L  P        KL+ ++ +    
Sbjct: 116 IDEAMSFAEMLK-LVQTMDYATIVFDTAPTGHTLRLLQFPATLEKGLSKLMSLKSRFGGL 174

Query: 179 RRAITKIQG-EQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIA 237
              ++++ G E +F              EDA++  L+  +D I+         + T+ + 
Sbjct: 175 MTQMSRMFGMEDEF-------------GEDALLGRLEGLKDVIE--------QDMTTFVC 213

Query: 238 VMNPEFLPLYETKRAYESLKKFKIPFNMVVMNKVIKLKREIPE--IRVKLEAQEKVLSEV 295
           V  PEFL LYET+R  + L KF+I  + +++N+V+    ++    +R ++  Q+K L + 
Sbjct: 214 VCIPEFLSLYETERLVQELAKFEIDTHNIIINQVLYDDEDVESKLLRARMRMQQKYLDQF 273

Query: 296 KREFPGVEIVEIPMFQEEPRGIEWL 320
              +    I ++P+  EE  G+E L
Sbjct: 274 YMLYDDFNITKLPLLPEEVTGVEAL 298


>gi|6320103 Ydl100cp [Saccharomyces cerevisiae]
           >gi|6647438|sp|Q12154|ARSA_YEAST PUTATIVE ARSENICAL
           PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING ATPASE)
           (ARSENICAL RESISTANCE ATPASE) >gi|2131333|pir||S67642
           probable arsenical pump-driving ATPase (EC 3.6.1.-)
           YDL100c - yeast (Saccharomyces cerevisiae)
           >gi|1199549|emb|CAA64913.1| (X95644) ORF 2371
           [Saccharomyces cerevisiae] >gi|1431138|emb|CAA98667.1|
           (Z74148) ORF YDL100c [Saccharomyces cerevisiae]
           Length = 354
           
 Score =  122 bits (303), Expect = 6e-27
 Identities = 92/333 (27%), Positives = 159/333 (47%), Gaps = 38/333 (11%)

Query: 14  IFVIGKGGVGKTTSSASISV--ALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--I 69
           IFV GKGGVGKTTSS SI++  AL++   + L++S DPAHNL D F EK     R++  +
Sbjct: 21  IFVGGKGGVGKTTSSCSIAIQMALSQPNKQFLLISTDPAHNLSDAFGEKFGKDARKVTGM 80

Query: 70  DNLYASELDMEGMIKGYLEHLEKNLKNMYR------YLTVINLEKYFEVLRYSPGIEEYA 123
           +NL   E+D    +K   +       N           +++      ++    PGI+E  
Sbjct: 81  NNLSCMEIDPSAALKDMNDMAVSRANNNGSDGQGDDLGSLLQGGALADLTGSIPGIDEAL 140

Query: 124 TLEAI-----REILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILER 178
           +   +     R+   +G+ +D ++FDT PTG TLR L LP       EK  +I  K+   
Sbjct: 141 SFMEVMKHIKRQEQGEGETFDTVIFDTAPTGHTLRFLQLPNTLSKLLEKFGEITNKL--- 197

Query: 179 RRAITKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAV 238
              +    G     I G+             + ELKA    ++ +    T+P+ T+ + V
Sbjct: 198 GPMLNSFMGAGNVDISGK-------------LNELKA---NVETIRQQFTDPDLTTFVCV 241

Query: 239 MNPEFLPLYETKRAYESLKKFKIPFNMVVMNKVIKLKRE----IPEIRVKLEAQEKVLSE 294
              EFL LYET+R  + L  + +  N +++N+++  + +        + + + Q+K L +
Sbjct: 242 CISEFLSLYETERLIQELISYDMDVNSIIVNQLLFAENDQEHNCKRCQARWKMQKKYLDQ 301

Query: 295 VKREFPGVEIVEIPMFQEEPRGIEWLSKVGEMI 327
           +   +    +V++P+   E RG+  L+K  + +
Sbjct: 302 IDELYEDFHVVKMPLCAGEIRGLNNLTKFSQFL 334


>gb|AAG18929.1| (AE004994) arsenical pump-driving ATPase; ArsA1 [Halobacterium sp.
           NRC-1]
           Length = 347
           
 Score =  119 bits (295), Expect = 5e-26
 Identities = 91/334 (27%), Positives = 158/334 (47%), Gaps = 61/334 (18%)

Query: 18  GKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREIIDN--LYAS 75
           GKGGVGKTT +A+ +VA A  G  TL+VS DPAH+L D    ++  +P  I +N  L+A 
Sbjct: 28  GKGGVGKTTMAAATAVASASDGTNTLVVSTDPAHSLSDTLEAEIPSRPHRIRENVPLWAV 87

Query: 76  ELD------------MEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFE-----VLRYSPG 118
           E+D             +G + G LE             T++  +              PG
Sbjct: 88  EIDPDDALDRTGMFGQDGALSGTLE-------------TMLGGDAGAPGGGDGSAAMMPG 134

Query: 119 IEEYATLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILER 178
            +E A ++ + E L   D +D +V DT PTG TLR+L LP +      +L+ +R+++   
Sbjct: 135 ADEAAAMQLLLEYL-DDDRFDRVVVDTAPTGHTLRLLELPEVMDSMVGQLMQVRERLGGM 193

Query: 179 RRAITKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAV 238
              +T + G       G++         +  M +L A ++ ++ +  VLT+P +T    V
Sbjct: 194 MDGLTGMFG-------GDD-----DASAEQTMGDLDAVKERVEQLRAVLTDPQRTDFRVV 241

Query: 239 MNPEFLPLYETKRAYESLKKFKIPFNMVVMNKVIKLKREIPEIRV--------------- 283
           + PE L + E+ R    L ++ +P N VV+N+V++   ++ ++                 
Sbjct: 242 LVPEELSVAESNRLITRLDEYGVPVNTVVVNRVMEPLADVADVPADAFVAPNHEDCAFCA 301

Query: 284 -KLEAQEKVLSEVKREFPGVEIVEIPMFQEEPRG 316
            + + Q++ L++ +  F G  +  +P+  EE RG
Sbjct: 302 RRWDVQQQALADAQDIFRGHTVKRVPLLAEEVRG 335


>sp|P30632|ARSA_CAEEL PUTATIVE ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING
           ATPASE) (ARSENICAL RESISTANCE ATPASE)
           >gi|102496|pir||S15791 probable arsenical pump-driving
           ATPase (EC 3.6.1.-) - Caenorhabditis elegans
           >gi|3881667|emb|CAA77452.1| (Z11115) predicted using
           Genefinder~ArsA homologue~cDNA EST yk62f10.5 comes from
           this gene~cDNA EST yk62f10.3 comes from this gene~cDNA
           EST yk176c11.3 comes from this gene~cDNA EST yk176c11.5
           comes from this gene~cDNA EST yk140f3.3 comes from this
           gene>
           Length = 342
           
 Score =  117 bits (291), Expect = 1e-25
 Identities = 95/332 (28%), Positives = 161/332 (47%), Gaps = 34/332 (10%)

Query: 14  IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPR--EIIDN 71
           IFV GKGGVGKTT S S++  L+K   R L++S DPAHN+ D F +K +  P   E   N
Sbjct: 21  IFVGGKGGVGKTTCSCSLAAQLSKVRERVLLISTDPAHNISDAFSQKFTKTPTLVEGFKN 80

Query: 72  LYASELDM----EGMIKGYLEHLEKNLKNMYRYLTVINLEKYF--EVLRYSPGIEEYATL 125
           L+A E+D     EG+  G +E + +N           ++ K F        PGI+E  + 
Sbjct: 81  LFAMEIDSNPNGEGVEMGNIEEMLQNAAQNEGGSGGFSMGKDFLQSFAGGLPGIDEAMSF 140

Query: 126 -EAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITK 184
            E I+  L+   ++DV+VFDT PTG TLR+L  P +       L  +  KIL  +     
Sbjct: 141 GEMIK--LIDSLDFDVVVFDTAPTGHTLRLLQFPTL-------LEKVFTKILSLQGMFGP 191

Query: 185 IQGE--QKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPE 242
           +  +    F + G  +        + ++ ++    + +K +     +PN T+ + V   E
Sbjct: 192 MMNQFGGMFGMGGGSM--------NEMIEKMTTTLESVKKMNAQFKDPNCTTFVCVCIAE 243

Query: 243 FLPLYETKRAYESLKKFKIPFNMVVMNKVIKLKRE------IPEIRVKLEAQEKVLSEVK 296
           FL LYET+R  + L K  I  + +++N+++    +        +   +   Q K L+++ 
Sbjct: 244 FLSLYETERLIQELSKQGIDTHNIIVNQLLFPDTDANGTVSCRKCASRQAIQSKYLTDID 303

Query: 297 REFPGVEIVEIPMFQEEPRGIEWLSKVGEMIV 328
             +    +V++P+ + E RG   + +  E +V
Sbjct: 304 ELYEDFHVVKLPLLEAEVRGGPAILQFSERMV 335


>gi|10803670 arsA [Halobacterium sp. NRC-1] >gi|6647419|sp|O52027|ARSA_HALSA
           PUTATIVE ARSENICAL PUMP-DRIVING ATPASE
           (ARSENITE-TRANSLOCATING ATPASE) (ARSENICAL RESISTANCE
           ATPASE) >gi|7436455|pir||T08340 probable arsenical
           pump-driving ATPase (EC 3.6.1.-) H1450 - Halobacterium
           sp. (strain NRC-1) plasmid pNRC100
           >gi|2822401|gb|AAC82907.1| (AF016485) arsA
           [Halobacterium sp. NRC-1]
           Length = 644
           
 Score =  115 bits (284), Expect = 1e-24
 Identities = 101/339 (29%), Positives = 160/339 (46%), Gaps = 56/339 (16%)

Query: 3   EFLTPKEGFRVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLS 62
           E L P E  R +F  GKGGVGK+T +++ +V+LA+AGY TL+V+ DPA +L D+F + + 
Sbjct: 335 EELVPVEETRYLFFTGKGGVGKSTIASTTAVSLAEAGYETLVVTTDPAAHLADIFEQPVG 394

Query: 63  DKPREIID-NLYASELDMEGMIKGYLEHLEKNLKNMYR---------YLTVINLEKYFEV 112
            +P  +   NL A+ +D E  ++ Y   +  +++ MY             V N+E+  E 
Sbjct: 395 HEPTSVGQANLDAARIDQERALEEYRTQVLDHVREMYDEKDDTQIDVEAAVANVEEELE- 453

Query: 113 LRYSPGIEEYATLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIR 172
              SP  EE A LE       + D +D++VFDT PTG TLR+L LP              
Sbjct: 454 ---SPCAEEMAALEKFVSYF-EEDGYDIVVFDTAPTGHTLRLLELP-------------- 495

Query: 173 KKILERRRAITKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNK 232
                          + K  +D   +       + A       Y + I+ ++D    P++
Sbjct: 496 --------------SDWKGFMDLGSL------TKGAAPANGGKYDEVIETMQD----PSR 531

Query: 233 TSVIAVMNPEFLPLYETKRAYESLK-KFKIPFNMVVMNKVIKLKREIPEIRVKLEAQE-K 290
           +S   VM PEF P+ E  RA   L+ +  I  ++VV N ++              AQ+ +
Sbjct: 532 SSFAFVMYPEFTPMMEAYRAAMDLQDQVGIETSVVVANYLLPEDYGDNAFFENRRAQQAE 591

Query: 291 VLSEVKREFPGVEIVEIPMFQEEPRGIEWLSKVGEMIVG 329
            L E+   F  V ++  P+ QEEP G++ L + G  + G
Sbjct: 592 YLEEISERF-DVPMMLAPLRQEEPVGLDDLREFGADVTG 629


 Score = 92.8 bits (227), Expect = 5e-18
 Identities = 89/330 (26%), Positives = 146/330 (43%), Gaps = 43/330 (13%)

Query: 2   REFLTPK-EGFRVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEK 60
           +E + P  E    +F  GKGGVGK+T S + +  LA   Y TL+V+ DPA NL D+F + 
Sbjct: 9   KEVVEPNSEDTEFVFFSGKGGVGKSTVSCATATWLADNDYDTLLVTTDPAPNLSDIFNQD 68

Query: 61  LSDKPREIID--NLYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPG 118
           +  +   I D  NL A E+D +   +   E+ ++ ++ M   L    ++   E L  SP 
Sbjct: 69  IGHEVTAIDDVPNLSAIEIDPDVAAE---EYRQETIEPMRALLGDEEIQTVEEQLN-SPC 124

Query: 119 IEEYATLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILER 178
           +EE A  +   + +    E+DV+VFDT PTG T+R++ LP       EK           
Sbjct: 125 VEEIAAFDNFVDFM-DSPEYDVVVFDTAPTGHTIRLMELPSDWNAELEK----------- 172

Query: 179 RRAITKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAV 238
                           G     P    +D         + + +   D L++ ++TS   V
Sbjct: 173 ---------------GGSTCIGPAASMDDK--------KADYERAIDTLSDESRTSFAFV 209

Query: 239 MNPEFLPLYETKRAYESLKKFKIPFNMVVMNKVI-KLKREIPEIRVKLEAQEKVLSEVKR 297
             PE   + E +R+   L +  I   ++V+N  + +   E P    K   ++ V+  V+ 
Sbjct: 210 GKPESSSIDEIERSASDLAELGISSQLLVVNGYLPESVCEDPFFEGKRADEQAVIDRVES 269

Query: 298 EFPGVEIVEIPMFQEEPRGIEWLSKVGEMI 327
            F    +   P+   E  G+E LS VG ++
Sbjct: 270 TFDQQALATYPLQPGEIAGLELLSDVGGVL 299


>gb|AAD51849.1|AF178758_5 (AF178758) ArsA [Sinorhizobium sp. As4]
           Length = 587
           
 Score =  107 bits (264), Expect = 2e-22
 Identities = 88/315 (27%), Positives = 143/315 (44%), Gaps = 40/315 (12%)

Query: 14  IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--IDN 71
           +F  GKGGVGKT+++ + ++ LA  G + L++S DPA NL DVF  +L++KP+EI  + N
Sbjct: 16  LFFTGKGGVGKTSTACATAITLADMGKQVLLISTDPASNLQDVFEIELTNKPKEIPSVPN 75

Query: 72  LYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFE--VLRYSPGIEEYATLEAIR 129
           L  + LD E     Y E +    +       +  +E+             +E++TL   +
Sbjct: 76  LQVANLDPETAAYEYKERVVGPYRGKLPDAVIATMEEQLSGACTVEMAAFDEFSTLLTNK 135

Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189
           E+  K   +D I+FDT PTG TLR+L LP     W+          LE         G  
Sbjct: 136 ELTSK---FDHIIFDTAPTGHTLRLLQLP---TAWS--------GFLEESTHGASCLGPL 181

Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249
             + D +E+   T +                      L+NPN+T ++ V  P+  PL E 
Sbjct: 182 AGLGDKKELYSQTVQ---------------------ALSNPNQTMLLLVTRPDSSPLQEA 220

Query: 250 KRAYESLKKFKIPFNMVVMNKVIKLKREIPEI-RVKLEAQEKVLSEVKREFPGVEIVEIP 308
            RA + LK+  +    +++N V+    +   I +     Q + L  +  E  G+   E+P
Sbjct: 221 GRAAKELKEIGVNNQYLLINGVLTNYVQNDAISKALFTRQVRALENMSEELKGLPAYELP 280

Query: 309 MFQEEPRGIEWLSKV 323
           +      GIE + K+
Sbjct: 281 LVPFNVTGIENMRKL 295


 Score = 77.3 bits (187), Expect = 2e-13
 Identities = 82/315 (26%), Positives = 138/315 (43%), Gaps = 59/315 (18%)

Query: 10  GFRVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREII 69
           G RVIF +GKGGVGKTT +++I+V LA+ G+R  + + DPA ++  V   +         
Sbjct: 328 GKRVIFTMGKGGVGKTTVASAIAVGLAEKGHRVHLTTTDPAAHIDYVMHGEQG------- 380

Query: 70  DNLYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129
            N+  S +D +  ++ Y + + +  K+      +  LE   E LR SP  EE A   A+ 
Sbjct: 381 -NITISRIDPKVEVENYRKEVIEQAKDTVDEEGLAYLE---EDLR-SPCTEEIAVFRALA 435

Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189
           +I+   ++ +++V DT PTG TL +L   +                    + I +  GE 
Sbjct: 436 DIVEIAND-EIVVIDTAPTGHTLLLLDAAQ-----------------TYHKEIARSSGE- 476

Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249
                                         +K +   L NP +TSV+ V   E  P++E 
Sbjct: 477 --------------------------VPQSVKNLLPRLRNPEETSVVIVTLAEATPVHEA 510

Query: 250 KRAYESLKKFKIPFNMVVMNKVIKLKREI-PEIRVKLEAQEKVLSEVKREFPGVEIVEIP 308
            R    LK+ +I     V+N+       I P ++ + +++   + EV++E      V IP
Sbjct: 511 SRLQGDLKRAEIHPKWWVINQSFYATHTIDPVLKGRSQSEVPWIQEVQKESQH-NCVIIP 569

Query: 309 MFQEEPRGIEWLSKV 323
              E+  G E L ++
Sbjct: 570 WQSEDVIGYEKLKEL 584


>gb|AAD15826.1| (AF061178) arsenical resistance ATPase [Mus musculus]
           Length = 193
           
 Score = 97.1 bits (238), Expect = 2e-19
 Identities = 62/151 (41%), Positives = 85/151 (56%), Gaps = 12/151 (7%)

Query: 14  IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--IDN 71
           IFV GKGGVGKTT S S++V L+K     LI+S DPAHN+ D F +K S  P ++   DN
Sbjct: 40  IFVGGKGGVGKTTCSCSLAVQLSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDN 99

Query: 72  LYASELDMEGMIKGYLEHL--EKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129
           L+A E+D    +    +    E N+ +M + +         E +   PGI+E  +   + 
Sbjct: 100 LFAMEIDPSLGVAELPDEFFEEDNMLSMGKKMMQ-------EAMSAFPGIDEAMSYAEVM 152

Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRI 160
             LVKG  + V+VFDT PTG TLR+L  P I
Sbjct: 153 R-LVKGMNFSVVVFDTAPTGHTLRLLNFPTI 182


>pir||H72523 probable arsenite-translocating ATPase APE2165 - Aeropyrum pernix
           (strain K1) >gi|5105864|dbj|BAA81176.1| (AP000063) 197aa
           long hypothetical arsenite-translocating ATPase
           [Aeropyrum pernix]
           Length = 197
           
 Score = 96.0 bits (235), Expect = 5e-19
 Identities = 63/190 (33%), Positives = 98/190 (51%), Gaps = 19/190 (10%)

Query: 132 LVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQKF 191
           L +   +  +V DTPPTGLTLR+L+LPR+   W E LI IR++I+  R  I +  G +  
Sbjct: 9   LYRDSRFKYVVVDTPPTGLTLRILSLPRLYTFWLESLIGIRERIVSLRYVIARSIGREP- 67

Query: 192 VIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYETKR 251
                       E +D V+ +L+  +D    + + L    +TS   V  PE LP+YE ++
Sbjct: 68  ------------EMDDPVLDKLREMQDRYAKLSNDLVERERTSFAIVATPEPLPVYEARK 115

Query: 252 AYESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEKVLSEVKREF---PGVEIVEIP 308
             E L+      +++V+N++  L  EI      LE Q K L+E++      P V +VEIP
Sbjct: 116 TVEFLESMGAKPSIIVVNRI--LPAEIASRLGVLEVQSKALNELRTRVCRKPCV-LVEIP 172

Query: 309 MFQEEPRGIE 318
           M +  P  +E
Sbjct: 173 MVETVPSSLE 182


>gb|AAF89640.1|AF168737_3 (AF168737) ArsA [Klebsiella oxytoca]
           Length = 585
           
 Score = 81.9 bits (199), Expect = 9e-15
 Identities = 70/264 (26%), Positives = 115/264 (43%), Gaps = 41/264 (15%)

Query: 14  IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSD--KPREIIDN 71
           +F  GKGGVGKT+ S + ++ LA+ G R L+VS DPA N+G VF + + +  +P   +  
Sbjct: 11  LFFTGKGGVGKTSISCATAIRLAEQGKRVLLVSTDPASNVGQVFDQAIGNTIRPVTAVHG 70

Query: 72  LYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAIREI 131
           L A E+D +   + Y   +   +K +     V ++ +            E A  +    +
Sbjct: 71  LSALEIDPQNAAQQYRARIVDPIKGLLPDDVVNSISEQLS----GACTTEIAAFDEFTGL 126

Query: 132 LVKG---DEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGE 188
           L  G     +D I+FDT PTG T+R+L LP     W+  +                   E
Sbjct: 127 LTDGFLLTRFDHIIFDTAPTGHTIRLLQLPG---AWSSFI-------------------E 164

Query: 189 QKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYE 248
            K   DG     P        M  L+  R++     + L++P +T ++ V   +   L E
Sbjct: 165 SK--PDGASCLGP--------MAGLEKQREQYAHAVEALSDPERTRLVLVARLQKSTLQE 214

Query: 249 TKRAYESLKKFKIPFNMVVMNKVI 272
             R +E L    +    +V+N V+
Sbjct: 215 VARTHEELSAIGLKNQYLVINGVL 238


>pir||A25937 arsenical pump-driving ATPase (EC 3.6.1.-) - Escherichia coli
           plasmid R773
           Length = 583
           
 Score = 78.0 bits (189), Expect = 1e-13
 Identities = 67/263 (25%), Positives = 113/263 (42%), Gaps = 39/263 (14%)

Query: 14  IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--IDN 71
           +F  GKGGVGKT+ S + ++ LA+ G R L+VS DPA N+G VF + + +  + I  +  
Sbjct: 11  LFFTGKGGVGKTSISCATAIRLAEQGKRVLLVSTDPASNVGQVFSQTIGNTIQAIASVPG 70

Query: 72  LYASELDMEGMIKGYLEHLEKNLKNMY--RYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129
           L A E+D +   + Y   +   +K +     ++ IN +            +E+  L    
Sbjct: 71  LSALEIDPQAAAQQYRARIVDPIKGVLPDDVVSSINEQLSGACTTEIAAFDEFTGLLTDT 130

Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189
            +L +   +D I+FDT PTG T+R+L LP                            G  
Sbjct: 131 SLLTR---FDHIIFDTAPTGHTIRLLQLP----------------------------GAW 159

Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249
              ID      P        M  L+  R++  +  + L++P +T ++ V   +   L E 
Sbjct: 160 SSFIDSN----PEGASCLGPMAGLEKQREQYAYAVEALSDPKRTRLVLVARLQKSTLQEV 215

Query: 250 KRAYESLKKFKIPFNMVVMNKVI 272
            R +  L    +    +V+N V+
Sbjct: 216 ARTHLELAAIGLKNQYLVINGVL 238


>pdb|1F48|A Chain A, Crystal Structure Of The Escherichia Coli Arsenite-
           Translocating Atpase
           Length = 589
           
 Score = 78.0 bits (189), Expect = 1e-13
 Identities = 67/263 (25%), Positives = 113/263 (42%), Gaps = 39/263 (14%)

Query: 14  IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--IDN 71
           +F  GKGGVGKT+ S + ++ LA+ G R L+VS DPA N+G VF + + +  + I  +  
Sbjct: 11  LFFTGKGGVGKTSISCATAIRLAEQGKRVLLVSTDPASNVGQVFSQTIGNTIQAIASVPG 70

Query: 72  LYASELDMEGMIKGYLEHLEKNLKNMY--RYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129
           L A E+D +   + Y   +   +K +     ++ IN +            +E+  L    
Sbjct: 71  LSALEIDPQAAAQQYRARIVDPIKGVLPDDVVSSINEQLSGACTTEIAAFDEFTGLLTDA 130

Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189
            +L +   +D I+FDT PTG T+R+L LP                            G  
Sbjct: 131 SLLTR---FDHIIFDTAPTGHTIRLLQLP----------------------------GAW 159

Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249
              ID      P        M  L+  R++  +  + L++P +T ++ V   +   L E 
Sbjct: 160 SSFIDSN----PEGASCLGPMAGLEKQREQYAYAVEALSDPKRTRLVLVARLQKSTLQEV 215

Query: 250 KRAYESLKKFKIPFNMVVMNKVI 272
            R +  L    +    +V+N V+
Sbjct: 216 ARTHLELAAIGLKNQYLVINGVL 238


>sp|O50593|ARSA_ACIMU ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING ATPASE)
           (ARSENICAL RESISTANCE ATPASE)
           >gi|2879919|dbj|BAA24822.1| (AB004659) ArsA
           [Acidiphilium multivorum]
           Length = 583
           
 Score = 77.6 bits (188), Expect = 2e-13
 Identities = 68/263 (25%), Positives = 115/263 (42%), Gaps = 39/263 (14%)

Query: 14  IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSD--KPREIIDN 71
           +F  GKGGVGKT+ S + ++ LA+ G R L+VS DPA N+G VF   + +  +P   +  
Sbjct: 11  LFFTGKGGVGKTSISCATAIHLAEQGKRVLLVSTDPASNVGQVFDLAIGNTIRPVTAVPG 70

Query: 72  LYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFE--VLRYSPGIEEYATLEAIR 129
           L A E+D +   + Y   +   +K +     V ++ +             +E+  L    
Sbjct: 71  LSALEIDPQEAARQYRARIVDPIKGLLPDDVVNSISEQLSGACTTEIAAFDEFTGLLTDA 130

Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189
            +L +   +D I+FDT PTG T+R+L LP     W+          +E            
Sbjct: 131 SLLTR---FDHIIFDTAPTGHTIRLLQLPG---AWS--------SFIESNP--------- 167

Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249
               DG     P        M  L+  R++     + L++P +T ++ V   +   L E 
Sbjct: 168 ----DGASCLGP--------MAGLEKQREQYAHAVEALSDPERTRLVLVARLQNSTLQEV 215

Query: 250 KRAYESLKKFKIPFNMVVMNKVI 272
            R +E L +  +    +V+N V+
Sbjct: 216 ARTHEELAEIGLKNQYLVINGVL 238


>sp|P52145|ARA2_ECOLI ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING ATPASE)
           (ARSENICAL RESISTANCE ATPASE) >gi|1061416|gb|AAB09626.1|
           (U38947) ArsA [Plasmid R46]
           Length = 583
           
 Score = 76.5 bits (185), Expect = 4e-13
 Identities = 67/268 (25%), Positives = 115/268 (42%), Gaps = 39/268 (14%)

Query: 14  IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSD--KPREIIDN 71
           +F  GKGGVGKT+ S + ++ LA+ G R L+VS DPA N+G VF + + +  +P   +  
Sbjct: 11  LFFTGKGGVGKTSISCATAIRLAELGKRVLLVSTDPASNVGQVFDQTIGNTIQPVTAVSG 70

Query: 72  LYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFE--VLRYSPGIEEYATLEAIR 129
           L A E+D +   + Y   +   +  +     V ++ +             +E+  L    
Sbjct: 71  LSALEIDPQDAAQQYRARIVDPIIGLLPDDVVNSISEQLSGACTTEIAAFDEFTGLLTDA 130

Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189
            +L +   +D I+FDT PTG T+R+L LP     W+          +E            
Sbjct: 131 SLLTR---FDHIIFDTAPTGHTIRLLQLPG---AWS--------SFIESNP--------- 167

Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249
               DG     P        M  L+  R++     + L++P +T ++ V   +   L E 
Sbjct: 168 ----DGASCLGP--------MAGLEKQREQYAHAVEALSDPERTRLVLVARLQKSTLQEV 215

Query: 250 KRAYESLKKFKIPFNMVVMNKVIKLKRE 277
            R ++ L    +    +V+N V+    E
Sbjct: 216 ARTHDELSAIGLKNQYLVINGVLPASEE 243


>sp|P08690|ARA1_ECOLI ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING ATPASE)
           (ARSENICAL RESISTANCE ATPASE) >gi|151857|gb|AAA21094.1|
           (J02591) ArsA [Plasmid R773]
           Length = 583
           
 Score = 76.5 bits (185), Expect = 4e-13
 Identities = 67/263 (25%), Positives = 112/263 (42%), Gaps = 39/263 (14%)

Query: 14  IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--IDN 71
           +F  GKGGVGKT+ S + ++ LA+ G R L+VS DPA N+G VF + +    + I  +  
Sbjct: 11  LFFTGKGGVGKTSISCATAIRLAEQGKRVLLVSTDPASNVGQVFSQTIGITIQAIASVPG 70

Query: 72  LYASELDMEGMIKGYLEHLEKNLKNMY--RYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129
           L A E+D +   + Y   +   +K +     ++ IN +            +E+  L    
Sbjct: 71  LSALEIDPQAAAQQYRARIVDPIKGVLPDDVVSSINEQLSGACTTEIAAFDEFTGLLTDA 130

Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189
            +L +   +D I+FDT PTG T+R+L LP                            G  
Sbjct: 131 SLLTR---FDHIIFDTAPTGHTIRLLQLP----------------------------GAW 159

Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249
              ID      P        M  L+  R++  +  + L++P +T ++ V   +   L E 
Sbjct: 160 SSFIDSN----PEGASCLGPMAGLEKQREQYAYAVEALSDPKRTRLVLVARLQKSTLQEV 215

Query: 250 KRAYESLKKFKIPFNMVVMNKVI 272
            R +  L    +    +V+N V+
Sbjct: 216 ARTHLELAAIGLKNQYLVINGVL 238


>pir||T36563 probable ion-transporting ATPase - Streptomyces coelicolor
           >gi|5139632|emb|CAB45559.1| (AL079353) putative
           ion-transporting ATPase [Streptomyces coelicolor A3(2)]
           Length = 481
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 45/156 (28%), Positives = 84/156 (53%), Gaps = 13/156 (8%)

Query: 12  RVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLG-DVFMEKLSDKPREI-- 68
           R++   G GGVGKTT++A++ +  A+ G + +++++DPA  L   + ++ L + PR +  
Sbjct: 50  RIVVCCGSGGVGKTTTAAALGLRAAERGRKVVVLTIDPARRLAQSMGIDSLDNTPRRVKG 109

Query: 69  IDN-----LYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYA 123
           +D+     L+A  LDM    K   + + ++  +  R   ++    Y  +     G +EY 
Sbjct: 110 VDDSAGGELHAMMLDM----KRTFDEIVESHADPERAAAILGNPFYQSLSAGFAGTQEYM 165

Query: 124 TLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPR 159
            +E + ++  + DEWD+IV DTPP+   L  L  P+
Sbjct: 166 AMEKLGQLRSR-DEWDLIVVDTPPSRSALDFLDAPK 200


>pir||A70791 probable anion transporting ATPase - Mycobacterium tuberculosis
           (strain H37RV) >gi|2960104|emb|CAA18002.1| (AL022121)
           hypothetical protein Rv3680 [Mycobacterium tuberculosis]
           Length = 386
           
 Score = 69.9 bits (168), Expect = 4e-11
 Identities = 45/155 (29%), Positives = 80/155 (51%), Gaps = 12/155 (7%)

Query: 12  RVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVF-MEKLSDKPR---- 66
           RV+   G GGVGKTT++A++++  A+ G   +++++DPA  L     +  L + P+    
Sbjct: 20  RVVVCCGAGGVGKTTTAAALALRAAEYGRTVVVLTIDPAKRLAQALGINDLGNTPQRVPL 79

Query: 67  --EIIDNLYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYAT 124
             E+   L+A  LDM    +   + +        R  ++++ + Y  V     G +EY  
Sbjct: 80  APEVPGELHAMMLDM----RRTFDEMVMQYSGPERAQSILDNQFYQTVATSLAGTQEYMA 135

Query: 125 LEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPR 159
           +E + ++L + D WD+IV DTPP+   L  L  P+
Sbjct: 136 MEKLGQLLSQ-DRWDLIVVDTPPSRNALDFLDAPK 169


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.319    0.139    0.388 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 117811944
Number of Sequences: 2977
Number of extensions: 4911432
Number of successful extensions: 20304
Number of sequences better than 1.0e-10: 33
Number of HSP's better than  0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 20216
Number of HSP's gapped (non-prelim): 49
length of query: 330
length of database: 189,106,746
effective HSP length: 58
effective length of query: 272
effective length of database: 154,394,500
effective search space: 41995304000
effective search space used: 41995304000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 165 (68.7 bits)