BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1555 (PAB1555) DE:ANION TRANSPORTING ATPASE (330 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||D75032 anion transporting atpase PAB1555 - Pyrococcus abyss... 651 0.0 sp|O27555|ARSA_METTH PUTATIVE ARSENICAL PUMP-DRIVING ATPASE (ARS... 190 1e-47 dbj|BAB05514.1| (AP001513) arsenical pump-driving ATPase [Bacill... 174 1e-42 sp|Q58542|ARSA_METJA PUTATIVE ARSENICAL PUMP-DRIVING ATPASE (ARS... 172 4e-42 emb|CAC11579.1| (AL445064) arsenite translocating ATPase (ASNA1)... 157 2e-37 sp|O66674|ARS2_AQUAE PUTATIVE ARSENICAL PUMP-DRIVING ATPASE 2 (A... 156 4e-37 sp|O66908|ARS1_AQUAE PUTATIVE ARSENICAL PUMP-DRIVING ATPASE 1 (A... 147 2e-34 gb|AAF59231.1| (AE003840) CG1598 gene product [Drosophila melano... 143 4e-33 emb|CAB77013.1| (AL159951) putative arsenite-translocating atpas... 138 9e-32 gb|AAA18794.1| (U09867) unknown [Chlorobium vibrioforme] >gi|109... 136 3e-31 gi|4757796 arsA (bacterial) arsenite transporter, ATP-binding, h... 135 6e-31 sp|O54984|ARS1_MOUSE ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRA... 135 8e-31 sp|O43681|ARS1_HUMAN ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRA... 135 8e-31 gi|11525963 arsA (bacterial) arsenite transporter, ATP-binding, ... 135 8e-31 gb|AAC03551.1| (AF047469) arsenite translocating ATPase [Homo sa... 134 1e-30 sp|Q55794|ARSA_SYNY3 PUTATIVE ARSENICAL PUMP-DRIVING ATPASE (ARS... 132 7e-30 dbj|BAB09846.1| (AB005246) arsenite translocating ATPase-like pr... 125 5e-28 gb|AAF76469.1|AC020622_3 (AC020622) Contains similarity to arsen... 125 7e-28 gi|6320103 Ydl100cp [Saccharomyces cerevisiae] >gi|6647438|sp|Q1... 122 6e-27 gb|AAG18929.1| (AE004994) arsenical pump-driving ATPase; ArsA1 [... 119 5e-26 sp|P30632|ARSA_CAEEL PUTATIVE ARSENICAL PUMP-DRIVING ATPASE (ARS... 117 1e-25 gi|10803670 arsA [Halobacterium sp. NRC-1] >gi|6647419|sp|O52027... 115 1e-24 gb|AAD51849.1|AF178758_5 (AF178758) ArsA [Sinorhizobium sp. As4] 107 2e-22 gb|AAD15826.1| (AF061178) arsenical resistance ATPase [Mus muscu... 97 2e-19 pir||H72523 probable arsenite-translocating ATPase APE2165 - Aer... 96 5e-19 gb|AAF89640.1|AF168737_3 (AF168737) ArsA [Klebsiella oxytoca] 82 9e-15 pir||A25937 arsenical pump-driving ATPase (EC 3.6.1.-) - Escheri... 78 1e-13 pdb|1F48|A Chain A, Crystal Structure Of The Escherichia Coli Ar... 78 1e-13 sp|O50593|ARSA_ACIMU ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRA... 78 2e-13 sp|P52145|ARA2_ECOLI ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRA... 76 4e-13 sp|P08690|ARA1_ECOLI ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRA... 76 4e-13 pir||T36563 probable ion-transporting ATPase - Streptomyces coel... 71 2e-11 pir||A70791 probable anion transporting ATPase - Mycobacterium t... 70 4e-11 >pir||D75032 anion transporting atpase PAB1555 - Pyrococcus abyssi (strain Orsay) >gi|5458666|emb|CAB50153.1| (AJ248287) ANION TRANSPORTING ATPASE [Pyrococcus abyssi] Length = 330 Score = 651 bits (1662), Expect = 0.0 Identities = 330/330 (100%), Positives = 330/330 (100%) Query: 1 MREFLTPKEGFRVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEK 60 MREFLTPKEGFRVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEK Sbjct: 1 MREFLTPKEGFRVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEK 60 Query: 61 LSDKPREIIDNLYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIE 120 LSDKPREIIDNLYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIE Sbjct: 61 LSDKPREIIDNLYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIE 120 Query: 121 EYATLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRR 180 EYATLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRR Sbjct: 121 EYATLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRR 180 Query: 181 AITKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMN 240 AITKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMN Sbjct: 181 AITKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMN 240 Query: 241 PEFLPLYETKRAYESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEKVLSEVKREFP 300 PEFLPLYETKRAYESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEKVLSEVKREFP Sbjct: 241 PEFLPLYETKRAYESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEKVLSEVKREFP 300 Query: 301 GVEIVEIPMFQEEPRGIEWLSKVGEMIVGR 330 GVEIVEIPMFQEEPRGIEWLSKVGEMIVGR Sbjct: 301 GVEIVEIPMFQEEPRGIEWLSKVGEMIVGR 330 >sp|O27555|ARSA_METTH PUTATIVE ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING ATPASE) (ARSENICAL RESISTANCE ATPASE) >gi|7428325|pir||F69068 probable arsenical pump-driving ATPase (EC 3.6.1.-) - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622629|gb|AAB85986.1| (AE000911) arsenical pump-driving ATPase [Methanobacterium thermoautotrophicum] Length = 324 Score = 190 bits (479), Expect = 1e-47 Identities = 103/316 (32%), Positives = 187/316 (58%), Gaps = 13/316 (4%) Query: 14 IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREIIDNLY 73 +F+ GKGGVGKTT SA+ ++ +A++G +TL++S DPAH+L D ++ P +I +NLY Sbjct: 17 VFIGGKGGVGKTTISAATALWMARSGKKTLVISTDPAHSLSDSLEREIGHTPTKITENLY 76 Query: 74 ASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAIREILV 133 A E+D E ++ Y L++ M + + L+ ++ SPGI+E A + + Sbjct: 77 AVEIDPEVAMEEYQAKLQEQAA-MNPGMGLDMLQDQMDMASMSPGIDEAAAFDQFLRYMT 135 Query: 134 KGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQKFVI 193 DE+D+++FDT PTG TLR+L+ P I W K+I IR++I +A I Sbjct: 136 T-DEYDIVIFDTAPTGHTLRLLSFPEIMDSWVGKMIKIRRQIGSMAKAFKNI-----LPF 189 Query: 194 DGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYETKRAY 253 G+E EEED +++++A + +I +V+++P +TS V+ PE + +YE++RA Sbjct: 190 MGDE------EEEDRALQDMEATKKQINAAREVMSDPERTSFKMVVIPEEMSIYESERAM 243 Query: 254 ESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEKVLSEVKREFPGVEIVEIPMFQEE 313 ++L+K+ I + V++N+V+ + + + + Q++ L +++ +F + E+P+ ++E Sbjct: 244 KALEKYSIHADGVIVNQVLPEESDCEFCNARRKLQQERLKQIREKFSDKVVAEVPLLKKE 303 Query: 314 PRGIEWLSKVGEMIVG 329 +GIE L K+ E + G Sbjct: 304 AKGIETLEKIAEQLYG 319 >dbj|BAB05514.1| (AP001513) arsenical pump-driving ATPase [Bacillus halodurans] Length = 313 Score = 174 bits (436), Expect = 1e-42 Identities = 97/309 (31%), Positives = 173/309 (55%), Gaps = 17/309 (5%) Query: 13 VIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREIIDNL 72 + F+ GKGGVGK+TS+AS + A+ G +TL++S DPAHNLGD+F ++ K ++I DNL Sbjct: 9 IYFIGGKGGVGKSTSAASFAWRCAERGEKTLLISTDPAHNLGDLFHTEIGAKHKKITDNL 68 Query: 73 YASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAIREIL 132 +A+E+D E + Y++ ++ NL+ M + + + + + +PG +E A AI I+ Sbjct: 69 FATEIDPEQETRRYIQSVKDNLRGMVKSTMLDEVNRQIDAAAATPGADEAAMFNAISSIV 128 Query: 133 V-KGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQKF 191 + + +D +VFDT PTG T+R+L LP + VW + ++ RKKI E Sbjct: 129 LDEQGTYDKLVFDTAPTGHTIRLLTLPEMMGVWIDGMVKKRKKINE---------NYSNL 179 Query: 192 VIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYETKR 251 + DGE + +D + L+ ++ V +VL +P KT + V+ PE LP+ ET++ Sbjct: 180 LNDGEPV-------DDPIYDTLQQRKERFAAVRNVLLDPKKTGFMFVLIPERLPILETEK 232 Query: 252 AYESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEKVLSEVKREFPGVEIVEIPMFQ 311 A + L K + +++NK++ + + + + +++ L ++ F ++ +P+F Sbjct: 233 AVKLLAKHDLHVETLIINKILPDVADGQFLEKRRQIEQRYLQQIHNTFRKQTLLRVPLFP 292 Query: 312 EEPRGIEWL 320 E+ IE L Sbjct: 293 EDIGSIEAL 301 >sp|Q58542|ARSA_METJA PUTATIVE ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING ATPASE) (ARSENICAL RESISTANCE ATPASE) >gi|2127768|pir||E64442 probable arsenical pump-driving ATPase (EC 3.6.1.-) - Methanococcus jannaschii >gi|1591774|gb|AAB99142.1| (U67556) arsenical pump-driving ATPase (arsA) [Methanococcus jannaschii] Length = 349 Score = 172 bits (432), Expect = 4e-42 Identities = 106/327 (32%), Positives = 186/327 (56%), Gaps = 14/327 (4%) Query: 5 LTPKEGFRVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDK 64 L K+G + I GKGGVGKTT SA+ V LA+ G + +IVS DPAH+L D+F ++ + Sbjct: 20 LEKKDGTKYIMFGGKGGVGKTTMSAATGVYLAEKGLKVVIVSTDPAHSLRDIFEQEFGHE 79 Query: 65 PREI--IDNLYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIEEY 122 P ++ DNLY E+D + ++ Y E L+ ++ +L + LE E+ SPG +E Sbjct: 80 PTKVKGYDNLYVVEIDPQKAMEEYKEKLKAQIEEN-PFLGEM-LEDQLEMAALSPGTDES 137 Query: 123 ATLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAI 182 A + + + +E+DV++FDT PTG TLR L +P + + KLI +RK++ + + Sbjct: 138 AAFDVFLKYM-DSNEFDVVIFDTAPTGHTLRFLGMPEVMDKYMTKLIKLRKQMSGFMKMM 196 Query: 183 TKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPE 242 K+ F E+I + D ++ EL+ ++ I ++L++P +T+ V+ PE Sbjct: 197 KKLL---PFGGKDEDI------DYDKMLEELEKMKERIVRARNILSDPERTAFRLVVIPE 247 Query: 243 FLPLYETKRAYESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEKVLSEVKREFPGV 302 + + E++RA ++L+K+ IP + V++N++I + R + E Q K L +K +F Sbjct: 248 EMSILESERAMKALQKYGIPIDAVIVNQLIPEDVQCDFCRARRELQLKRLEMIKEKFGDK 307 Query: 303 EIVEIPMFQEEPRGIEWLSKVGEMIVG 329 I +P+ + E +GIE L ++ +++ G Sbjct: 308 VIAYVPLLRTEAKGIETLKQIAKILYG 334 >emb|CAC11579.1| (AL445064) arsenite translocating ATPase (ASNA1) related protein [Thermoplasma acidophilum] Length = 387 Score = 157 bits (393), Expect = 2e-37 Identities = 100/321 (31%), Positives = 175/321 (54%), Gaps = 23/321 (7%) Query: 12 RVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREIIDN 71 R++ GKGGVGKT+ +A+ L+ G++TLI+S DPAH+LGD F ++ +++ DN Sbjct: 4 RILLYTGKGGVGKTSIAAATGALLSSKGHKTLIISTDPAHSLGDAFGMEIGHSIKQLADN 63 Query: 72 LYASELDMEGMIKGYLEHLEKNLKNMY--RYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129 LY E+ + I + L+ L++++ + L ++ ++ + PG EE + L +R Sbjct: 64 LYGQEVSVVQSINEHWGELKDYLRSLFLSQGLDPVSADE----IATLPGFEEASELLYLR 119 Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189 +E+D I+ D+ PTG L++L+ P + + +KL I +K R + K Sbjct: 120 NYYY-DEEYDTIIMDSAPTGAALQLLSFPEVMTWYMDKLFPISRKTARVARPLLK----- 173 Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249 FV +I LP EDAV + ++ + +LTN + TS+ V NP+ + ET Sbjct: 174 PFV----DIPLP----EDAVFENIDLLYRQLTDIRKILTNNDVTSIRLVTNPDNMSYSET 225 Query: 250 KRAYESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEK-VLSEVKREFPGVEIVEIP 308 KRAY L + P + V++NK+ L E + K+ +K +++E++ F ++I + Sbjct: 226 KRAYTYLLLYGYPVDAVIINKI--LSDETGDFFEKMRGSQKDIITEMENSFVDIKIFKAR 283 Query: 309 MFQEEPRGIEWLSKVGEMIVG 329 + QEEP GI+ L ++G++I G Sbjct: 284 LLQEEPIGIKKLIELGKLIYG 304 >sp|O66674|ARS2_AQUAE PUTATIVE ARSENICAL PUMP-DRIVING ATPASE 2 (ARSENITE-TRANSLOCATING ATPASE 2) (ARSENICAL RESISTANCE ATPASE 2) >gi|7428326|pir||F70330 probable arsenical pump-driving ATPase (EC 3.6.1.-) - Aquifex aeolicus >gi|2983014|gb|AAC06625.1| (AE000684) anion transporting ATPase [Aquifex aeolicus] Length = 299 Score = 156 bits (390), Expect = 4e-37 Identities = 99/317 (31%), Positives = 168/317 (52%), Gaps = 23/317 (7%) Query: 12 RVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREIIDN 71 RV F GKGGVGKTT+S++ +V L++ G + L++S DPAH+L DVF +L + + + +N Sbjct: 2 RVFFFGGKGGVGKTTASSAFAVKLSEQGKKVLLLSTDPAHSLSDVFNTELQGETK-LSEN 60 Query: 72 LYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAI-RE 130 L E+D+ +K Y + K + R T+ LE L SPGIE+ EA+ +E Sbjct: 61 LTVKEIDLNEELKEYRSRVFKLAEATLRKETLRELEGIIHSLEESPGIEDVVIFEALSKE 120 Query: 131 ILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQK 190 ++ + +E+D IV DT PTG TL +L R + E+++ +++K+ E + Sbjct: 121 VVYRENEYDYIVVDTAPTGHTLGLLKTVRNLGNFLEEIVKLKEKVYELK----------- 169 Query: 191 FVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYETK 250 KL + + + LK ++ K +++ +K+ AV+ PE LP ETK Sbjct: 170 --------KLSGKSVHEEALEYLKERKERFKKFSEIIY--DKSYFFAVLTPEKLPFEETK 219 Query: 251 RAYESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEKVLSEVKREFPGVEIVEIPMF 310 R SLK + I +++NKV+ + ++ + E ++K L E++ F +E + IP Sbjct: 220 RLVNSLKHYGIRVKALIINKVLPENPQDEFLKARKEVEKKFLKEIENYFMDIEKISIPYQ 279 Query: 311 QEEPRGIEWLSKVGEMI 327 +EE G E L + + + Sbjct: 280 KEEVVGYEKLKEFSKFL 296 >sp|O66908|ARS1_AQUAE PUTATIVE ARSENICAL PUMP-DRIVING ATPASE 1 (ARSENITE-TRANSLOCATING ATPASE 1) (ARSENICAL RESISTANCE ATPASE 1) >gi|7451716|pir||H70359 anion transporting ATPase - Aquifex aeolicus >gi|2983270|gb|AAC06864.1| (AE000701) anion transporting ATPase [Aquifex aeolicus] Length = 396 Score = 147 bits (367), Expect = 2e-34 Identities = 103/333 (30%), Positives = 177/333 (52%), Gaps = 36/333 (10%) Query: 12 RVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVF------MEKLSDKP 65 R+I GKGGVGKTT SA+ L++ G + ++VSLDPAH+L D F K P Sbjct: 2 RIILFSGKGGVGKTTISAATGYKLSQLGKKVIVVSLDPAHSLADSFDVPEEERRKAKGLP 61 Query: 66 REIIDNLYASELDMEGMIKGYLEHLEKNLKNMYRYLTVI-----NLEKYFEVLRYSPGIE 120 +I +NL E+D++ E +E+ +YR++ ++ E + L PG+E Sbjct: 62 IKINENLEIQEIDIQ-------EEIERYWGEVYRFIELLFHTTGLHEILADELAILPGME 114 Query: 121 EYATLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRR 180 E +L + + +G+ DV++ D PPTG ++R +++P + + W KKI + R Sbjct: 115 EITSLLYVNKYYREGNH-DVLILDLPPTGESIRFVSMPTV-MKW------YMKKIFKTER 166 Query: 181 AITKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMN 240 I K+ G +P +EE + L+ + + +K V+++L NP+ TS+ V N Sbjct: 167 LIMKVARPTV----GRMTDVPLPDEE--YFKALETFYERLKGVDEILINPDITSIRIVSN 220 Query: 241 PEFLPLYETKRAYESLKKFKIPFNMVVMNKVIK---LKREIPEIRVK-LEAQEKVLSEVK 296 PE + L E++RA+ F + + V++NKVI +++E K L Q+K + E++ Sbjct: 221 PEKMVLKESQRAFLYFLLFGVNVDAVIVNKVIPEEVIQQENCSFLEKWLNIQKKYVKEIE 280 Query: 297 REFPGVEIVEIPMFQEEPRGIEWLSKVGEMIVG 329 F V + ++P+ +EE G+E L K+ ++I G Sbjct: 281 SYFSPVPVFKVPLLEEEVVGLERLEKLAQLIYG 313 >gb|AAF59231.1| (AE003840) CG1598 gene product [Drosophila melanogaster] Length = 336 Score = 143 bits (356), Expect = 4e-33 Identities = 96/329 (29%), Positives = 165/329 (49%), Gaps = 23/329 (6%) Query: 5 LTPKEGFRVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDK 64 L ++ + IFV GKGGVGKTT S+S++V L+K LI+S DPAHN+ D F +K + Sbjct: 15 LVEQDSLKWIFVGGKGGVGKTTCSSSLAVQLSKVRESVLIISTDPAHNISDAFDQKFTKV 74 Query: 65 PREI--IDNLYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIEEY 122 P ++ DNL+A E+D + E R ++ E++ PGI+E Sbjct: 75 PTKVNGFDNLFAMEIDPNAGLNELPEEYFDGENEALR----VSKGVMQEMINALPGIDEA 130 Query: 123 ATLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAI 182 + + + LVKG + V+VFDT PTG TLR++A P++ KL+ ++ K+ Sbjct: 131 MSYAEVMK-LVKGMNFSVVVFDTAPTGHTLRLIAFPQVVEKGLGKLLRLKMKVAPLLSQF 189 Query: 183 TKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPE 242 + G D KL D ++R + ++ K NP++T+ + V E Sbjct: 190 VSMLGMADVNADTLSQKL------DDMLRVITQVNEQFK-------NPDQTTFVCVCIAE 236 Query: 243 FLPLYETKRAYESLKKFKIPFNMVVMNKVIKLKREIPEIRV---KLEAQEKVLSEVKREF 299 F LYET+R + L K I + +++N+++ L+ + + + QEK L ++ + Sbjct: 237 FFSLYETERLVQELTKCGIDVHNIIVNQLLFLQNSHDSCSMCASRFKIQEKYLDQIADLY 296 Query: 300 PGVEIVEIPMFQEEPRGIEWLSKVGEMIV 328 + ++P+ ++E RG E + E ++ Sbjct: 297 EDFHVTKLPLLEKEVRGPESIRSFSENLM 325 >emb|CAB77013.1| (AL159951) putative arsenite-translocating atpase [Schizosaccharomyces pombe] Length = 329 Score = 138 bits (344), Expect = 9e-32 Identities = 100/331 (30%), Positives = 161/331 (48%), Gaps = 28/331 (8%) Query: 3 EFLTPKEGFRVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLS 62 E L + + IFV GKGGVGKTT+S S+++ ++K L++S DPAHNL D F K Sbjct: 11 ENLLEQTSLKWIFVGGKGGVGKTTTSCSLAIQMSKVRSSVLLISTDPAHNLSDAFGTKFG 70 Query: 63 DKPREI--IDNLYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIE 120 R++ DNL A E+D I+ E ++ +N L+ + + F + PGI+ Sbjct: 71 KDARKVPGFDNLSAMEIDPNLSIQEMTEQADQ--QNPNNPLSGMMQDLAFTI----PGID 124 Query: 121 EYATLEAIREIL--VKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILER 178 E A EIL +K E+D ++FDT PTG TLR L P + KL + + Sbjct: 125 EAL---AFAEILKQIKSMEFDCVIFDTAPTGHTLRFLNFPTVLEKALGKLGGLSSRFGPM 181 Query: 179 RRAITKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAV 238 + I G E + ++++ R I V NP+ T+ + V Sbjct: 182 INQMGSIMG--------------VNANEQDLFGKMESMRANISEVNKQFKNPDLTTFVCV 227 Query: 239 MNPEFLPLYETKRAYESLKKFKIPFNMVVMNK-VIKLKREIPEIRVKLEAQEKVLSEVKR 297 EFL LYET+R + L ++I + +V+N+ ++ P+ + + Q+K L++++ Sbjct: 228 CISEFLSLYETERMIQELTSYEIDTHNIVVNQLLLDPNTTCPQCMARRKMQQKYLAQIEE 287 Query: 298 EFPGVEIVEIPMFQEEPRGIEWLSKVGEMIV 328 + +V++P E RG E L EM+V Sbjct: 288 LYEDFHVVKVPQVPAEVRGTEALKSFSEMLV 318 >gb|AAA18794.1| (U09867) unknown [Chlorobium vibrioforme] >gi|1098330|prf||2115394E ORF Z [Chlorobium vibrioforme] Length = 405 Score = 136 bits (340), Expect = 3e-31 Identities = 99/325 (30%), Positives = 173/325 (52%), Gaps = 27/325 (8%) Query: 12 RVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREIIDN 71 R++ GKGGVGKT+ SA+ +V L++ G+RTL++S DPAH+L D F +L +P +I +N Sbjct: 2 RILTFTGKGGVGKTSVSAATAVRLSEMGHRTLVLSTDPAHSLSDSFNLQLGAEPTKIKEN 61 Query: 72 LYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEK-----YFEVLRYSPGIEEYATLE 126 L+A E + Y++ L++N ++ +Y T + + + + + PG+EE +L Sbjct: 62 LHAIE------VNPYVD-LKENWHSVQKYYTRVFMAQGVSGVMADEMTILPGMEELFSLL 114 Query: 127 AIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILER--RRAITK 184 I+ G +D +V DT PTG TLR+L+LP +L W K + K + R + ++K Sbjct: 115 RIKRYKSTG-LYDALVLDTAPTGETLRLLSLPD-TLSWGMKAVKNVNKYIVRPLSKPLSK 172 Query: 185 IQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFL 244 + + + I E+ E D V DE++ + D+LT+ K++V VMN E + Sbjct: 173 MSDKIAYYIPPED----AIESVDQVF-------DELEDIRDILTDNVKSTVRLVMNAEKM 221 Query: 245 PLYETKRAYESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEKVLSEVKREFPGVEI 304 + ET RA L + +MV++NK++ + + Q+K L E++ F + + Sbjct: 222 SIKETMRALTYLNLYGFKVDMVLVNKLLDAQENSGYLEKWKGIQQKYLGEIEEGFSPLPV 281 Query: 305 VEIPMFQEEPRGIEWLSKVGEMIVG 329 ++ M+ +E G++ L I G Sbjct: 282 KKLKMYDQEIVGVKSLEVFAHDIYG 306 >gi|4757796 arsA (bacterial) arsenite transporter, ATP-binding, homolog 1 [Homo sapiens] >gi|1616741|gb|AAC50731.1| (U60276) hASNA-I [Homo sapiens] Length = 332 Score = 135 bits (337), Expect = 6e-31 Identities = 103/323 (31%), Positives = 166/323 (50%), Gaps = 31/323 (9%) Query: 14 IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--IDN 71 IFV GKGGVGKTT S S++V L+K LI+S DPAHN+ D F +K S P ++ DN Sbjct: 24 IFVGGKGGVGKTTCSCSLAVQLSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDN 83 Query: 72 LYASELDMEGMIKGYLEHL--EKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129 L+A E+D + + E N+ +M + + E + PGI+E + + Sbjct: 84 LFAMEIDPSLGVADVPDEFFEEDNMLSMGKKMMQ-------EAMSAFPGIDEAMSYAEVM 136 Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189 LVKG + V+VFDT PTG TLR+L P I +L+ I+ +I + + G Sbjct: 137 R-LVKGMNFSVVVFDTAPTGHTLRLLNFPTIVERGLGRLMQIKNQISPFISQMCNMLG-- 193 Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249 + D +L ++ EE + I+ V + +P +T+ I V EFL LYET Sbjct: 194 --LGDMNADQLASKLEETLPV---------IRSVSEQFKDPEQTTFICVCIAEFLSLYET 242 Query: 250 KRAYESLKKFKIPFNMVVMNKVIKLKREIP----EIRVKLEAQEKVLSEVKREFPGVEIV 305 +R + L K KI + +++N+++ E P E R K++A K L +++ + IV Sbjct: 243 ERLIQELAKCKIDTHNIIVNQLVFPDPEKPCKMCEARHKIQA--KYLDQMEDLYEDFHIV 300 Query: 306 EIPMFQEEPRGIEWLSKVGEMIV 328 ++P+ E RG + ++ +++ Sbjct: 301 KLPLLPHEVRGADKVNTFSALLL 323 >sp|O54984|ARS1_MOUSE ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING ATPASE) (ARSENICAL RESISTANCE ATPASE) (ARSA) >gi|2745900|gb|AAB94772.1| (AF039405) arsenite-translocating ATPase [Mus musculus] Length = 350 Score = 135 bits (336), Expect = 8e-31 Identities = 103/323 (31%), Positives = 166/323 (50%), Gaps = 31/323 (9%) Query: 14 IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--IDN 71 IFV GKGGVGKTT S S++V L+K LI+S DPAHN+ D F +K S P ++ DN Sbjct: 40 IFVGGKGGVGKTTCSCSLAVQLSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDN 99 Query: 72 LYASELDMEGMIKGYLEHL--EKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129 L+A E+D + + E N+ +M + + E + PGI+E + + Sbjct: 100 LFAMEIDPSLGVAELPDEFFEEDNMLSMGKKMMQ-------EAMSAFPGIDEAMSYAEVM 152 Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189 LVKG + V+VFDT PTG TLR+L P I +L+ I+ +I + + G Sbjct: 153 R-LVKGMNFSVVVFDTAPTGHTLRLLNFPTIVERGLGRLMQIKNQISPFISQMCNMLG-- 209 Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249 + D +L ++ EE + I+ V + +P +T+ I V EFL LYET Sbjct: 210 --LGDMNADQLASKLEETLPV---------IRSVSEQFKDPEQTTFICVCIAEFLSLYET 258 Query: 250 KRAYESLKKFKIPFNMVVMNKVIKLKREIP----EIRVKLEAQEKVLSEVKREFPGVEIV 305 +R + L K KI + +++N+++ E P E R K++A K L +++ + IV Sbjct: 259 ERLIQELAKCKIDTHNIIVNQLVFPDPEKPCKMCEARHKIQA--KYLDQMEDLYEDFHIV 316 Query: 306 EIPMFQEEPRGIEWLSKVGEMIV 328 ++P+ E RG + ++ +++ Sbjct: 317 KLPLLPHEVRGADKVNTFSALLL 339 >sp|O43681|ARS1_HUMAN ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING ATPASE) (ARSENICAL RESISTANCE ATPASE) (ARSA) (ASNA-I) Length = 348 Score = 135 bits (336), Expect = 8e-31 Identities = 103/323 (31%), Positives = 166/323 (50%), Gaps = 31/323 (9%) Query: 14 IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--IDN 71 IFV GKGGVGKTT S S++V L+K LI+S DPAHN+ D F +K S P ++ DN Sbjct: 40 IFVGGKGGVGKTTCSCSLAVQLSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDN 99 Query: 72 LYASELDMEGMIKGYLEHL--EKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129 L+A E+D + + E N+ +M + + E + PGI+E + + Sbjct: 100 LFAMEIDPSLGVAELPDEFFEEDNMLSMGKKMMQ-------EAMSAFPGIDEAMSYAEVM 152 Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189 LVKG + V+VFDT PTG TLR+L P I +L+ I+ +I + + G Sbjct: 153 R-LVKGMNFSVVVFDTAPTGHTLRLLNFPTIVERGLGRLMQIKNQISPFISQMCNMLG-- 209 Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249 + D +L ++ EE + I+ V + +P +T+ I V EFL LYET Sbjct: 210 --LGDMNADQLASKLEETLPV---------IRSVSEQFKDPEQTTFICVCIAEFLSLYET 258 Query: 250 KRAYESLKKFKIPFNMVVMNKVIKLKREIP----EIRVKLEAQEKVLSEVKREFPGVEIV 305 +R + L K KI + +++N+++ E P E R K++A K L +++ + IV Sbjct: 259 ERLIQELAKCKIDTHNIIVNQLVFPDPEKPCKMCEARHKIQA--KYLDQMEDLYEDFHIV 316 Query: 306 EIPMFQEEPRGIEWLSKVGEMIV 328 ++P+ E RG + ++ +++ Sbjct: 317 KLPLLPHEVRGADKVNTFSALLL 339 >gi|11525963 arsA (bacterial) arsenite transporter, ATP-binding, homolog 1 [Homo sapiens] Length = 331 Score = 135 bits (336), Expect = 8e-31 Identities = 103/323 (31%), Positives = 166/323 (50%), Gaps = 31/323 (9%) Query: 14 IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--IDN 71 IFV GKGGVGKTT S S++V L+K LI+S DPAHN+ D F +K S P ++ DN Sbjct: 23 IFVGGKGGVGKTTCSCSLAVQLSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDN 82 Query: 72 LYASELDMEGMIKGYLEHL--EKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129 L+A E+D + + E N+ +M + + E + PGI+E + + Sbjct: 83 LFAMEIDPSLGVAELPDEFFEEDNMLSMGKKMMQ-------EAMSAFPGIDEAMSYAEVM 135 Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189 LVKG + V+VFDT PTG TLR+L P I +L+ I+ +I + + G Sbjct: 136 R-LVKGMNFSVVVFDTAPTGHTLRLLNFPTIVERGLGRLMQIKNQISPFISQMCNMLG-- 192 Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249 + D +L ++ EE + I+ V + +P +T+ I V EFL LYET Sbjct: 193 --LGDMNADQLASKLEETLPV---------IRSVSEQFKDPEQTTFICVCIAEFLSLYET 241 Query: 250 KRAYESLKKFKIPFNMVVMNKVIKLKREIP----EIRVKLEAQEKVLSEVKREFPGVEIV 305 +R + L K KI + +++N+++ E P E R K++A K L +++ + IV Sbjct: 242 ERLIQELAKCKIDTHNIIVNQLVFPDPEKPCKMCEARHKIQA--KYLDQMEDLYEDFHIV 299 Query: 306 EIPMFQEEPRGIEWLSKVGEMIV 328 ++P+ E RG + ++ +++ Sbjct: 300 KLPLLPHEVRGADKVNTFSALLL 322 >gb|AAC03551.1| (AF047469) arsenite translocating ATPase [Homo sapiens] Length = 348 Score = 134 bits (335), Expect = 1e-30 Identities = 103/323 (31%), Positives = 166/323 (50%), Gaps = 31/323 (9%) Query: 14 IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--IDN 71 IFV GKGGVGKTT S S++V L+K LI+S DPAHN+ D F +K S P ++ DN Sbjct: 40 IFVGGKGGVGKTTCSCSLAVQLSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDN 99 Query: 72 LYASELDMEGMIKGYLEHL--EKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129 L+A E+D + + E N+ +M + + E + PGI+E + + Sbjct: 100 LFAMEIDPSLGVAELPDEFFEEDNMLSMGKKMMQ-------EAMSAFPGIDEAMSYAEVM 152 Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189 LVKG + V+VFDT PTG TLR+L P I +L+ I+ +I + + G Sbjct: 153 R-LVKGMNFSVVVFDTAPTGHTLRLLNFPTIVERGLGRLMQIKNQISPFISQMFNMLG-- 209 Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249 + D +L ++ EE + I+ V + +P +T+ I V EFL LYET Sbjct: 210 --LGDMNADQLASKLEETLPV---------IRSVSEQFKDPEQTTFICVCIAEFLSLYET 258 Query: 250 KRAYESLKKFKIPFNMVVMNKVIKLKREIP----EIRVKLEAQEKVLSEVKREFPGVEIV 305 +R + L K KI + +++N+++ E P E R K++A K L +++ + IV Sbjct: 259 ERLIQELAKCKIDTHNIIVNQLVFPDPEKPCKMCEARHKIQA--KYLDQMEDLYEDFHIV 316 Query: 306 EIPMFQEEPRGIEWLSKVGEMIV 328 ++P+ E RG + ++ +++ Sbjct: 317 KLPLLPHEVRGADKVNTFSALLL 339 >sp|Q55794|ARSA_SYNY3 PUTATIVE ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING ATPASE) (ARSENICAL RESISTANCE ATPASE) >gi|7451715|pir||S76602 hypothetical protein - Synechocystis sp. (strain PCC 6803) >gi|1001709|dbj|BAA10546.1| (D64004) hypothetical protein [Synechocystis sp.] Length = 396 Score = 132 bits (328), Expect = 7e-30 Identities = 98/322 (30%), Positives = 166/322 (51%), Gaps = 24/322 (7%) Query: 12 RVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREIIDN 71 RVI + GKGGVGKT+ +A+ + A+ G++TL++S DPAH+L D F +L +PR + +N Sbjct: 2 RVILMTGKGGVGKTSVAAATGLRCAELGHKTLVLSTDPAHSLADSFDLELGHEPRLVKEN 61 Query: 72 LYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEK-----YFEVLRYSPGIEEYATLE 126 L+ +ELD L LE N + RY+T + + E L PG++E L Sbjct: 62 LWGAELDA-------LMELEGNWGAVKRYITQVLQARGLDGVQAEELAILPGMDEIFGLV 114 Query: 127 AIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQ 186 ++ + D +DV++ D+ PTG LR+L+LP + + + K L+ + Sbjct: 115 RMKRHYDEAD-YDVLIIDSAPTGTALRLLSLPEVGGWYMRRFY----KPLQGMSVALRPL 169 Query: 187 GEQKF-VIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLP 245 E F I G LP +E DA + ++I+ +E VLT+ +TSV V NPE + Sbjct: 170 VEPLFRPIAG--FSLPDKEVMDAPYE----FYEQIEALEKVLTDNTQTSVRLVTNPEKMV 223 Query: 246 LYETKRAYESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEKVLSEVKREFPGVEIV 305 L E+ RA+ L + + ++V+ N+++ + P + Q+ E+ F + + Sbjct: 224 LKESLRAHAYLSLYNVSTDLVIANRILPETIDDPFFQRWKSNQQVYKQEIYDNFHPLPVK 283 Query: 306 EIPMFQEEPRGIEWLSKVGEMI 327 E P+F EE G+ L ++ + + Sbjct: 284 EAPLFSEEMCGLAALERLKDTL 305 >dbj|BAB09846.1| (AB005246) arsenite translocating ATPase-like protein [Arabidopsis thaliana] Length = 417 Score = 125 bits (312), Expect = 5e-28 Identities = 94/330 (28%), Positives = 176/330 (52%), Gaps = 36/330 (10%) Query: 18 GKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSD---KPREIIDN-LY 73 GKGGVGKT+ +AS++V A G+ T++VS DPAH+L D F + LS KP + +D+ L Sbjct: 102 GKGGVGKTSCAASLAVKFASHGHPTIVVSTDPAHSLSDSFSQDLSGGVLKPVQGVDSPLL 161 Query: 74 ASELDMEGMIKGYLEHL--EKNLKNMYRYLTV---------INLEKYFEVLRYSPGIEEY 122 A E+ E ++K ++ +K++KNM + + +NLE SPGI+E Sbjct: 162 ALEITPE-IMKDEIKRQTGDKSVKNMMDSMGLGMFAGELGDLNLEDMLNAA--SPGIDEI 218 Query: 123 ATLEAIREILVKGD--EWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRR 180 A + + + + + + IVFDT PTG TLR+L+LP K+ ++KKI Sbjct: 219 AAISKVLQFMEAPEYSRFTRIVFDTAPTGHTLRLLSLPDFYDSSISKITKLKKKITAAAS 278 Query: 181 AITKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMN 240 A + G+++ ++ +LP EL ++ ++ V +V + + T + V Sbjct: 279 AFKLVFGKKEI----QQKELP---------NELDQLKERMEKVRNVFRDVDTTEFVIVTI 325 Query: 241 PEFLPLYETKRAYESLKKFKIPFNMVVMNKVI-KLKREIPEIRVKLEAQEKVLSEVKR-- 297 P + + E+ R + SL+K +P + +++N+++ + + + ++ + Q +VL ++ Sbjct: 326 PTVMAINESSRLHASLRKENVPVHRLIVNQLLPQSESDCKFCSIRRKEQTRVLGLIQNDT 385 Query: 298 EFPGVEIVEIPMFQEEPRGIEWLSKVGEMI 327 E G+++++ P+ E RG+ L +G++I Sbjct: 386 ELSGLKLIQSPLLDAEIRGVPALKFMGDLI 415 >gb|AAF76469.1|AC020622_3 (AC020622) Contains similarity to arsenite translocating ATPase from Homo sapiens gb|AF047469 and contains a 4Fe-4S iron sulfur cluster binding protein PF|00142 domain. EST gb|N37510 comes from this gene. [Arabidopsis thaliana] Length = 345 Score = 125 bits (311), Expect = 7e-28 Identities = 95/325 (29%), Positives = 158/325 (48%), Gaps = 54/325 (16%) Query: 8 KEGFRVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPRE 67 +E + +FV GKGGVGKTT S+ +++ LA LI+S DPAHNL D F ++ + P Sbjct: 16 QESLKWVFVGGKGGVGKTTCSSILAICLASVRSSVLIISTDPAHNLSDAFQQRFTKSPTL 75 Query: 68 I--IDNLYASEL-------DMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPG 118 + NL+A E+ DM G ++ L +L N PG Sbjct: 76 VQGFSNLFAMEVDPTVETDDMAG--TDGMDGLFSDLANAI------------------PG 115 Query: 119 IEEYATLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILER 178 I+E + + + LV+ ++ IVFDT PTG TLR+L P KL+ ++ + Sbjct: 116 IDEAMSFAEMLK-LVQTMDYATIVFDTAPTGHTLRLLQFPATLEKGLSKLMSLKSRFGGL 174 Query: 179 RRAITKIQG-EQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIA 237 ++++ G E +F EDA++ L+ +D I+ + T+ + Sbjct: 175 MTQMSRMFGMEDEF-------------GEDALLGRLEGLKDVIE--------QDMTTFVC 213 Query: 238 VMNPEFLPLYETKRAYESLKKFKIPFNMVVMNKVIKLKREIPE--IRVKLEAQEKVLSEV 295 V PEFL LYET+R + L KF+I + +++N+V+ ++ +R ++ Q+K L + Sbjct: 214 VCIPEFLSLYETERLVQELAKFEIDTHNIIINQVLYDDEDVESKLLRARMRMQQKYLDQF 273 Query: 296 KREFPGVEIVEIPMFQEEPRGIEWL 320 + I ++P+ EE G+E L Sbjct: 274 YMLYDDFNITKLPLLPEEVTGVEAL 298 >gi|6320103 Ydl100cp [Saccharomyces cerevisiae] >gi|6647438|sp|Q12154|ARSA_YEAST PUTATIVE ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING ATPASE) (ARSENICAL RESISTANCE ATPASE) >gi|2131333|pir||S67642 probable arsenical pump-driving ATPase (EC 3.6.1.-) YDL100c - yeast (Saccharomyces cerevisiae) >gi|1199549|emb|CAA64913.1| (X95644) ORF 2371 [Saccharomyces cerevisiae] >gi|1431138|emb|CAA98667.1| (Z74148) ORF YDL100c [Saccharomyces cerevisiae] Length = 354 Score = 122 bits (303), Expect = 6e-27 Identities = 92/333 (27%), Positives = 159/333 (47%), Gaps = 38/333 (11%) Query: 14 IFVIGKGGVGKTTSSASISV--ALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--I 69 IFV GKGGVGKTTSS SI++ AL++ + L++S DPAHNL D F EK R++ + Sbjct: 21 IFVGGKGGVGKTTSSCSIAIQMALSQPNKQFLLISTDPAHNLSDAFGEKFGKDARKVTGM 80 Query: 70 DNLYASELDMEGMIKGYLEHLEKNLKNMYR------YLTVINLEKYFEVLRYSPGIEEYA 123 +NL E+D +K + N +++ ++ PGI+E Sbjct: 81 NNLSCMEIDPSAALKDMNDMAVSRANNNGSDGQGDDLGSLLQGGALADLTGSIPGIDEAL 140 Query: 124 TLEAI-----REILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILER 178 + + R+ +G+ +D ++FDT PTG TLR L LP EK +I K+ Sbjct: 141 SFMEVMKHIKRQEQGEGETFDTVIFDTAPTGHTLRFLQLPNTLSKLLEKFGEITNKL--- 197 Query: 179 RRAITKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAV 238 + G I G+ + ELKA ++ + T+P+ T+ + V Sbjct: 198 GPMLNSFMGAGNVDISGK-------------LNELKA---NVETIRQQFTDPDLTTFVCV 241 Query: 239 MNPEFLPLYETKRAYESLKKFKIPFNMVVMNKVIKLKRE----IPEIRVKLEAQEKVLSE 294 EFL LYET+R + L + + N +++N+++ + + + + + Q+K L + Sbjct: 242 CISEFLSLYETERLIQELISYDMDVNSIIVNQLLFAENDQEHNCKRCQARWKMQKKYLDQ 301 Query: 295 VKREFPGVEIVEIPMFQEEPRGIEWLSKVGEMI 327 + + +V++P+ E RG+ L+K + + Sbjct: 302 IDELYEDFHVVKMPLCAGEIRGLNNLTKFSQFL 334 >gb|AAG18929.1| (AE004994) arsenical pump-driving ATPase; ArsA1 [Halobacterium sp. NRC-1] Length = 347 Score = 119 bits (295), Expect = 5e-26 Identities = 91/334 (27%), Positives = 158/334 (47%), Gaps = 61/334 (18%) Query: 18 GKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREIIDN--LYAS 75 GKGGVGKTT +A+ +VA A G TL+VS DPAH+L D ++ +P I +N L+A Sbjct: 28 GKGGVGKTTMAAATAVASASDGTNTLVVSTDPAHSLSDTLEAEIPSRPHRIRENVPLWAV 87 Query: 76 ELD------------MEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFE-----VLRYSPG 118 E+D +G + G LE T++ + PG Sbjct: 88 EIDPDDALDRTGMFGQDGALSGTLE-------------TMLGGDAGAPGGGDGSAAMMPG 134 Query: 119 IEEYATLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILER 178 +E A ++ + E L D +D +V DT PTG TLR+L LP + +L+ +R+++ Sbjct: 135 ADEAAAMQLLLEYL-DDDRFDRVVVDTAPTGHTLRLLELPEVMDSMVGQLMQVRERLGGM 193 Query: 179 RRAITKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAV 238 +T + G G++ + M +L A ++ ++ + VLT+P +T V Sbjct: 194 MDGLTGMFG-------GDD-----DASAEQTMGDLDAVKERVEQLRAVLTDPQRTDFRVV 241 Query: 239 MNPEFLPLYETKRAYESLKKFKIPFNMVVMNKVIKLKREIPEIRV--------------- 283 + PE L + E+ R L ++ +P N VV+N+V++ ++ ++ Sbjct: 242 LVPEELSVAESNRLITRLDEYGVPVNTVVVNRVMEPLADVADVPADAFVAPNHEDCAFCA 301 Query: 284 -KLEAQEKVLSEVKREFPGVEIVEIPMFQEEPRG 316 + + Q++ L++ + F G + +P+ EE RG Sbjct: 302 RRWDVQQQALADAQDIFRGHTVKRVPLLAEEVRG 335 >sp|P30632|ARSA_CAEEL PUTATIVE ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING ATPASE) (ARSENICAL RESISTANCE ATPASE) >gi|102496|pir||S15791 probable arsenical pump-driving ATPase (EC 3.6.1.-) - Caenorhabditis elegans >gi|3881667|emb|CAA77452.1| (Z11115) predicted using Genefinder~ArsA homologue~cDNA EST yk62f10.5 comes from this gene~cDNA EST yk62f10.3 comes from this gene~cDNA EST yk176c11.3 comes from this gene~cDNA EST yk176c11.5 comes from this gene~cDNA EST yk140f3.3 comes from this gene> Length = 342 Score = 117 bits (291), Expect = 1e-25 Identities = 95/332 (28%), Positives = 161/332 (47%), Gaps = 34/332 (10%) Query: 14 IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPR--EIIDN 71 IFV GKGGVGKTT S S++ L+K R L++S DPAHN+ D F +K + P E N Sbjct: 21 IFVGGKGGVGKTTCSCSLAAQLSKVRERVLLISTDPAHNISDAFSQKFTKTPTLVEGFKN 80 Query: 72 LYASELDM----EGMIKGYLEHLEKNLKNMYRYLTVINLEKYF--EVLRYSPGIEEYATL 125 L+A E+D EG+ G +E + +N ++ K F PGI+E + Sbjct: 81 LFAMEIDSNPNGEGVEMGNIEEMLQNAAQNEGGSGGFSMGKDFLQSFAGGLPGIDEAMSF 140 Query: 126 -EAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITK 184 E I+ L+ ++DV+VFDT PTG TLR+L P + L + KIL + Sbjct: 141 GEMIK--LIDSLDFDVVVFDTAPTGHTLRLLQFPTL-------LEKVFTKILSLQGMFGP 191 Query: 185 IQGE--QKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPE 242 + + F + G + + ++ ++ + +K + +PN T+ + V E Sbjct: 192 MMNQFGGMFGMGGGSM--------NEMIEKMTTTLESVKKMNAQFKDPNCTTFVCVCIAE 243 Query: 243 FLPLYETKRAYESLKKFKIPFNMVVMNKVIKLKRE------IPEIRVKLEAQEKVLSEVK 296 FL LYET+R + L K I + +++N+++ + + + Q K L+++ Sbjct: 244 FLSLYETERLIQELSKQGIDTHNIIVNQLLFPDTDANGTVSCRKCASRQAIQSKYLTDID 303 Query: 297 REFPGVEIVEIPMFQEEPRGIEWLSKVGEMIV 328 + +V++P+ + E RG + + E +V Sbjct: 304 ELYEDFHVVKLPLLEAEVRGGPAILQFSERMV 335 >gi|10803670 arsA [Halobacterium sp. NRC-1] >gi|6647419|sp|O52027|ARSA_HALSA PUTATIVE ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING ATPASE) (ARSENICAL RESISTANCE ATPASE) >gi|7436455|pir||T08340 probable arsenical pump-driving ATPase (EC 3.6.1.-) H1450 - Halobacterium sp. (strain NRC-1) plasmid pNRC100 >gi|2822401|gb|AAC82907.1| (AF016485) arsA [Halobacterium sp. NRC-1] Length = 644 Score = 115 bits (284), Expect = 1e-24 Identities = 101/339 (29%), Positives = 160/339 (46%), Gaps = 56/339 (16%) Query: 3 EFLTPKEGFRVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLS 62 E L P E R +F GKGGVGK+T +++ +V+LA+AGY TL+V+ DPA +L D+F + + Sbjct: 335 EELVPVEETRYLFFTGKGGVGKSTIASTTAVSLAEAGYETLVVTTDPAAHLADIFEQPVG 394 Query: 63 DKPREIID-NLYASELDMEGMIKGYLEHLEKNLKNMYR---------YLTVINLEKYFEV 112 +P + NL A+ +D E ++ Y + +++ MY V N+E+ E Sbjct: 395 HEPTSVGQANLDAARIDQERALEEYRTQVLDHVREMYDEKDDTQIDVEAAVANVEEELE- 453 Query: 113 LRYSPGIEEYATLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIR 172 SP EE A LE + D +D++VFDT PTG TLR+L LP Sbjct: 454 ---SPCAEEMAALEKFVSYF-EEDGYDIVVFDTAPTGHTLRLLELP-------------- 495 Query: 173 KKILERRRAITKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNK 232 + K +D + + A Y + I+ ++D P++ Sbjct: 496 --------------SDWKGFMDLGSL------TKGAAPANGGKYDEVIETMQD----PSR 531 Query: 233 TSVIAVMNPEFLPLYETKRAYESLK-KFKIPFNMVVMNKVIKLKREIPEIRVKLEAQE-K 290 +S VM PEF P+ E RA L+ + I ++VV N ++ AQ+ + Sbjct: 532 SSFAFVMYPEFTPMMEAYRAAMDLQDQVGIETSVVVANYLLPEDYGDNAFFENRRAQQAE 591 Query: 291 VLSEVKREFPGVEIVEIPMFQEEPRGIEWLSKVGEMIVG 329 L E+ F V ++ P+ QEEP G++ L + G + G Sbjct: 592 YLEEISERF-DVPMMLAPLRQEEPVGLDDLREFGADVTG 629 Score = 92.8 bits (227), Expect = 5e-18 Identities = 89/330 (26%), Positives = 146/330 (43%), Gaps = 43/330 (13%) Query: 2 REFLTPK-EGFRVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEK 60 +E + P E +F GKGGVGK+T S + + LA Y TL+V+ DPA NL D+F + Sbjct: 9 KEVVEPNSEDTEFVFFSGKGGVGKSTVSCATATWLADNDYDTLLVTTDPAPNLSDIFNQD 68 Query: 61 LSDKPREIID--NLYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPG 118 + + I D NL A E+D + + E+ ++ ++ M L ++ E L SP Sbjct: 69 IGHEVTAIDDVPNLSAIEIDPDVAAE---EYRQETIEPMRALLGDEEIQTVEEQLN-SPC 124 Query: 119 IEEYATLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILER 178 +EE A + + + E+DV+VFDT PTG T+R++ LP EK Sbjct: 125 VEEIAAFDNFVDFM-DSPEYDVVVFDTAPTGHTIRLMELPSDWNAELEK----------- 172 Query: 179 RRAITKIQGEQKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAV 238 G P +D + + + D L++ ++TS V Sbjct: 173 ---------------GGSTCIGPAASMDDK--------KADYERAIDTLSDESRTSFAFV 209 Query: 239 MNPEFLPLYETKRAYESLKKFKIPFNMVVMNKVI-KLKREIPEIRVKLEAQEKVLSEVKR 297 PE + E +R+ L + I ++V+N + + E P K ++ V+ V+ Sbjct: 210 GKPESSSIDEIERSASDLAELGISSQLLVVNGYLPESVCEDPFFEGKRADEQAVIDRVES 269 Query: 298 EFPGVEIVEIPMFQEEPRGIEWLSKVGEMI 327 F + P+ E G+E LS VG ++ Sbjct: 270 TFDQQALATYPLQPGEIAGLELLSDVGGVL 299 >gb|AAD51849.1|AF178758_5 (AF178758) ArsA [Sinorhizobium sp. As4] Length = 587 Score = 107 bits (264), Expect = 2e-22 Identities = 88/315 (27%), Positives = 143/315 (44%), Gaps = 40/315 (12%) Query: 14 IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--IDN 71 +F GKGGVGKT+++ + ++ LA G + L++S DPA NL DVF +L++KP+EI + N Sbjct: 16 LFFTGKGGVGKTSTACATAITLADMGKQVLLISTDPASNLQDVFEIELTNKPKEIPSVPN 75 Query: 72 LYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFE--VLRYSPGIEEYATLEAIR 129 L + LD E Y E + + + +E+ +E++TL + Sbjct: 76 LQVANLDPETAAYEYKERVVGPYRGKLPDAVIATMEEQLSGACTVEMAAFDEFSTLLTNK 135 Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189 E+ K +D I+FDT PTG TLR+L LP W+ LE G Sbjct: 136 ELTSK---FDHIIFDTAPTGHTLRLLQLP---TAWS--------GFLEESTHGASCLGPL 181 Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249 + D +E+ T + L+NPN+T ++ V P+ PL E Sbjct: 182 AGLGDKKELYSQTVQ---------------------ALSNPNQTMLLLVTRPDSSPLQEA 220 Query: 250 KRAYESLKKFKIPFNMVVMNKVIKLKREIPEI-RVKLEAQEKVLSEVKREFPGVEIVEIP 308 RA + LK+ + +++N V+ + I + Q + L + E G+ E+P Sbjct: 221 GRAAKELKEIGVNNQYLLINGVLTNYVQNDAISKALFTRQVRALENMSEELKGLPAYELP 280 Query: 309 MFQEEPRGIEWLSKV 323 + GIE + K+ Sbjct: 281 LVPFNVTGIENMRKL 295 Score = 77.3 bits (187), Expect = 2e-13 Identities = 82/315 (26%), Positives = 138/315 (43%), Gaps = 59/315 (18%) Query: 10 GFRVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREII 69 G RVIF +GKGGVGKTT +++I+V LA+ G+R + + DPA ++ V + Sbjct: 328 GKRVIFTMGKGGVGKTTVASAIAVGLAEKGHRVHLTTTDPAAHIDYVMHGEQG------- 380 Query: 70 DNLYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129 N+ S +D + ++ Y + + + K+ + LE E LR SP EE A A+ Sbjct: 381 -NITISRIDPKVEVENYRKEVIEQAKDTVDEEGLAYLE---EDLR-SPCTEEIAVFRALA 435 Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189 +I+ ++ +++V DT PTG TL +L + + I + GE Sbjct: 436 DIVEIAND-EIVVIDTAPTGHTLLLLDAAQ-----------------TYHKEIARSSGE- 476 Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249 +K + L NP +TSV+ V E P++E Sbjct: 477 --------------------------VPQSVKNLLPRLRNPEETSVVIVTLAEATPVHEA 510 Query: 250 KRAYESLKKFKIPFNMVVMNKVIKLKREI-PEIRVKLEAQEKVLSEVKREFPGVEIVEIP 308 R LK+ +I V+N+ I P ++ + +++ + EV++E V IP Sbjct: 511 SRLQGDLKRAEIHPKWWVINQSFYATHTIDPVLKGRSQSEVPWIQEVQKESQH-NCVIIP 569 Query: 309 MFQEEPRGIEWLSKV 323 E+ G E L ++ Sbjct: 570 WQSEDVIGYEKLKEL 584 >gb|AAD15826.1| (AF061178) arsenical resistance ATPase [Mus musculus] Length = 193 Score = 97.1 bits (238), Expect = 2e-19 Identities = 62/151 (41%), Positives = 85/151 (56%), Gaps = 12/151 (7%) Query: 14 IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--IDN 71 IFV GKGGVGKTT S S++V L+K LI+S DPAHN+ D F +K S P ++ DN Sbjct: 40 IFVGGKGGVGKTTCSCSLAVQLSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDN 99 Query: 72 LYASELDMEGMIKGYLEHL--EKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129 L+A E+D + + E N+ +M + + E + PGI+E + + Sbjct: 100 LFAMEIDPSLGVAELPDEFFEEDNMLSMGKKMMQ-------EAMSAFPGIDEAMSYAEVM 152 Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRI 160 LVKG + V+VFDT PTG TLR+L P I Sbjct: 153 R-LVKGMNFSVVVFDTAPTGHTLRLLNFPTI 182 >pir||H72523 probable arsenite-translocating ATPase APE2165 - Aeropyrum pernix (strain K1) >gi|5105864|dbj|BAA81176.1| (AP000063) 197aa long hypothetical arsenite-translocating ATPase [Aeropyrum pernix] Length = 197 Score = 96.0 bits (235), Expect = 5e-19 Identities = 63/190 (33%), Positives = 98/190 (51%), Gaps = 19/190 (10%) Query: 132 LVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQKF 191 L + + +V DTPPTGLTLR+L+LPR+ W E LI IR++I+ R I + G + Sbjct: 9 LYRDSRFKYVVVDTPPTGLTLRILSLPRLYTFWLESLIGIRERIVSLRYVIARSIGREP- 67 Query: 192 VIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYETKR 251 E +D V+ +L+ +D + + L +TS V PE LP+YE ++ Sbjct: 68 ------------EMDDPVLDKLREMQDRYAKLSNDLVERERTSFAIVATPEPLPVYEARK 115 Query: 252 AYESLKKFKIPFNMVVMNKVIKLKREIPEIRVKLEAQEKVLSEVKREF---PGVEIVEIP 308 E L+ +++V+N++ L EI LE Q K L+E++ P V +VEIP Sbjct: 116 TVEFLESMGAKPSIIVVNRI--LPAEIASRLGVLEVQSKALNELRTRVCRKPCV-LVEIP 172 Query: 309 MFQEEPRGIE 318 M + P +E Sbjct: 173 MVETVPSSLE 182 >gb|AAF89640.1|AF168737_3 (AF168737) ArsA [Klebsiella oxytoca] Length = 585 Score = 81.9 bits (199), Expect = 9e-15 Identities = 70/264 (26%), Positives = 115/264 (43%), Gaps = 41/264 (15%) Query: 14 IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSD--KPREIIDN 71 +F GKGGVGKT+ S + ++ LA+ G R L+VS DPA N+G VF + + + +P + Sbjct: 11 LFFTGKGGVGKTSISCATAIRLAEQGKRVLLVSTDPASNVGQVFDQAIGNTIRPVTAVHG 70 Query: 72 LYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYATLEAIREI 131 L A E+D + + Y + +K + V ++ + E A + + Sbjct: 71 LSALEIDPQNAAQQYRARIVDPIKGLLPDDVVNSISEQLS----GACTTEIAAFDEFTGL 126 Query: 132 LVKG---DEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGE 188 L G +D I+FDT PTG T+R+L LP W+ + E Sbjct: 127 LTDGFLLTRFDHIIFDTAPTGHTIRLLQLPG---AWSSFI-------------------E 164 Query: 189 QKFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYE 248 K DG P M L+ R++ + L++P +T ++ V + L E Sbjct: 165 SK--PDGASCLGP--------MAGLEKQREQYAHAVEALSDPERTRLVLVARLQKSTLQE 214 Query: 249 TKRAYESLKKFKIPFNMVVMNKVI 272 R +E L + +V+N V+ Sbjct: 215 VARTHEELSAIGLKNQYLVINGVL 238 >pir||A25937 arsenical pump-driving ATPase (EC 3.6.1.-) - Escherichia coli plasmid R773 Length = 583 Score = 78.0 bits (189), Expect = 1e-13 Identities = 67/263 (25%), Positives = 113/263 (42%), Gaps = 39/263 (14%) Query: 14 IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--IDN 71 +F GKGGVGKT+ S + ++ LA+ G R L+VS DPA N+G VF + + + + I + Sbjct: 11 LFFTGKGGVGKTSISCATAIRLAEQGKRVLLVSTDPASNVGQVFSQTIGNTIQAIASVPG 70 Query: 72 LYASELDMEGMIKGYLEHLEKNLKNMY--RYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129 L A E+D + + Y + +K + ++ IN + +E+ L Sbjct: 71 LSALEIDPQAAAQQYRARIVDPIKGVLPDDVVSSINEQLSGACTTEIAAFDEFTGLLTDT 130 Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189 +L + +D I+FDT PTG T+R+L LP G Sbjct: 131 SLLTR---FDHIIFDTAPTGHTIRLLQLP----------------------------GAW 159 Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249 ID P M L+ R++ + + L++P +T ++ V + L E Sbjct: 160 SSFIDSN----PEGASCLGPMAGLEKQREQYAYAVEALSDPKRTRLVLVARLQKSTLQEV 215 Query: 250 KRAYESLKKFKIPFNMVVMNKVI 272 R + L + +V+N V+ Sbjct: 216 ARTHLELAAIGLKNQYLVINGVL 238 >pdb|1F48|A Chain A, Crystal Structure Of The Escherichia Coli Arsenite- Translocating Atpase Length = 589 Score = 78.0 bits (189), Expect = 1e-13 Identities = 67/263 (25%), Positives = 113/263 (42%), Gaps = 39/263 (14%) Query: 14 IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--IDN 71 +F GKGGVGKT+ S + ++ LA+ G R L+VS DPA N+G VF + + + + I + Sbjct: 11 LFFTGKGGVGKTSISCATAIRLAEQGKRVLLVSTDPASNVGQVFSQTIGNTIQAIASVPG 70 Query: 72 LYASELDMEGMIKGYLEHLEKNLKNMY--RYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129 L A E+D + + Y + +K + ++ IN + +E+ L Sbjct: 71 LSALEIDPQAAAQQYRARIVDPIKGVLPDDVVSSINEQLSGACTTEIAAFDEFTGLLTDA 130 Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189 +L + +D I+FDT PTG T+R+L LP G Sbjct: 131 SLLTR---FDHIIFDTAPTGHTIRLLQLP----------------------------GAW 159 Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249 ID P M L+ R++ + + L++P +T ++ V + L E Sbjct: 160 SSFIDSN----PEGASCLGPMAGLEKQREQYAYAVEALSDPKRTRLVLVARLQKSTLQEV 215 Query: 250 KRAYESLKKFKIPFNMVVMNKVI 272 R + L + +V+N V+ Sbjct: 216 ARTHLELAAIGLKNQYLVINGVL 238 >sp|O50593|ARSA_ACIMU ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING ATPASE) (ARSENICAL RESISTANCE ATPASE) >gi|2879919|dbj|BAA24822.1| (AB004659) ArsA [Acidiphilium multivorum] Length = 583 Score = 77.6 bits (188), Expect = 2e-13 Identities = 68/263 (25%), Positives = 115/263 (42%), Gaps = 39/263 (14%) Query: 14 IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSD--KPREIIDN 71 +F GKGGVGKT+ S + ++ LA+ G R L+VS DPA N+G VF + + +P + Sbjct: 11 LFFTGKGGVGKTSISCATAIHLAEQGKRVLLVSTDPASNVGQVFDLAIGNTIRPVTAVPG 70 Query: 72 LYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFE--VLRYSPGIEEYATLEAIR 129 L A E+D + + Y + +K + V ++ + +E+ L Sbjct: 71 LSALEIDPQEAARQYRARIVDPIKGLLPDDVVNSISEQLSGACTTEIAAFDEFTGLLTDA 130 Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189 +L + +D I+FDT PTG T+R+L LP W+ +E Sbjct: 131 SLLTR---FDHIIFDTAPTGHTIRLLQLPG---AWS--------SFIESNP--------- 167 Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249 DG P M L+ R++ + L++P +T ++ V + L E Sbjct: 168 ----DGASCLGP--------MAGLEKQREQYAHAVEALSDPERTRLVLVARLQNSTLQEV 215 Query: 250 KRAYESLKKFKIPFNMVVMNKVI 272 R +E L + + +V+N V+ Sbjct: 216 ARTHEELAEIGLKNQYLVINGVL 238 >sp|P52145|ARA2_ECOLI ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING ATPASE) (ARSENICAL RESISTANCE ATPASE) >gi|1061416|gb|AAB09626.1| (U38947) ArsA [Plasmid R46] Length = 583 Score = 76.5 bits (185), Expect = 4e-13 Identities = 67/268 (25%), Positives = 115/268 (42%), Gaps = 39/268 (14%) Query: 14 IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSD--KPREIIDN 71 +F GKGGVGKT+ S + ++ LA+ G R L+VS DPA N+G VF + + + +P + Sbjct: 11 LFFTGKGGVGKTSISCATAIRLAELGKRVLLVSTDPASNVGQVFDQTIGNTIQPVTAVSG 70 Query: 72 LYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFE--VLRYSPGIEEYATLEAIR 129 L A E+D + + Y + + + V ++ + +E+ L Sbjct: 71 LSALEIDPQDAAQQYRARIVDPIIGLLPDDVVNSISEQLSGACTTEIAAFDEFTGLLTDA 130 Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189 +L + +D I+FDT PTG T+R+L LP W+ +E Sbjct: 131 SLLTR---FDHIIFDTAPTGHTIRLLQLPG---AWS--------SFIESNP--------- 167 Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249 DG P M L+ R++ + L++P +T ++ V + L E Sbjct: 168 ----DGASCLGP--------MAGLEKQREQYAHAVEALSDPERTRLVLVARLQKSTLQEV 215 Query: 250 KRAYESLKKFKIPFNMVVMNKVIKLKRE 277 R ++ L + +V+N V+ E Sbjct: 216 ARTHDELSAIGLKNQYLVINGVLPASEE 243 >sp|P08690|ARA1_ECOLI ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING ATPASE) (ARSENICAL RESISTANCE ATPASE) >gi|151857|gb|AAA21094.1| (J02591) ArsA [Plasmid R773] Length = 583 Score = 76.5 bits (185), Expect = 4e-13 Identities = 67/263 (25%), Positives = 112/263 (42%), Gaps = 39/263 (14%) Query: 14 IFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVFMEKLSDKPREI--IDN 71 +F GKGGVGKT+ S + ++ LA+ G R L+VS DPA N+G VF + + + I + Sbjct: 11 LFFTGKGGVGKTSISCATAIRLAEQGKRVLLVSTDPASNVGQVFSQTIGITIQAIASVPG 70 Query: 72 LYASELDMEGMIKGYLEHLEKNLKNMY--RYLTVINLEKYFEVLRYSPGIEEYATLEAIR 129 L A E+D + + Y + +K + ++ IN + +E+ L Sbjct: 71 LSALEIDPQAAAQQYRARIVDPIKGVLPDDVVSSINEQLSGACTTEIAAFDEFTGLLTDA 130 Query: 130 EILVKGDEWDVIVFDTPPTGLTLRVLALPRISLVWTEKLIDIRKKILERRRAITKIQGEQ 189 +L + +D I+FDT PTG T+R+L LP G Sbjct: 131 SLLTR---FDHIIFDTAPTGHTIRLLQLP----------------------------GAW 159 Query: 190 KFVIDGEEIKLPTREEEDAVMRELKAYRDEIKFVEDVLTNPNKTSVIAVMNPEFLPLYET 249 ID P M L+ R++ + + L++P +T ++ V + L E Sbjct: 160 SSFIDSN----PEGASCLGPMAGLEKQREQYAYAVEALSDPKRTRLVLVARLQKSTLQEV 215 Query: 250 KRAYESLKKFKIPFNMVVMNKVI 272 R + L + +V+N V+ Sbjct: 216 ARTHLELAAIGLKNQYLVINGVL 238 >pir||T36563 probable ion-transporting ATPase - Streptomyces coelicolor >gi|5139632|emb|CAB45559.1| (AL079353) putative ion-transporting ATPase [Streptomyces coelicolor A3(2)] Length = 481 Score = 71.0 bits (171), Expect = 2e-11 Identities = 45/156 (28%), Positives = 84/156 (53%), Gaps = 13/156 (8%) Query: 12 RVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLG-DVFMEKLSDKPREI-- 68 R++ G GGVGKTT++A++ + A+ G + +++++DPA L + ++ L + PR + Sbjct: 50 RIVVCCGSGGVGKTTTAAALGLRAAERGRKVVVLTIDPARRLAQSMGIDSLDNTPRRVKG 109 Query: 69 IDN-----LYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYA 123 +D+ L+A LDM K + + ++ + R ++ Y + G +EY Sbjct: 110 VDDSAGGELHAMMLDM----KRTFDEIVESHADPERAAAILGNPFYQSLSAGFAGTQEYM 165 Query: 124 TLEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPR 159 +E + ++ + DEWD+IV DTPP+ L L P+ Sbjct: 166 AMEKLGQLRSR-DEWDLIVVDTPPSRSALDFLDAPK 200 >pir||A70791 probable anion transporting ATPase - Mycobacterium tuberculosis (strain H37RV) >gi|2960104|emb|CAA18002.1| (AL022121) hypothetical protein Rv3680 [Mycobacterium tuberculosis] Length = 386 Score = 69.9 bits (168), Expect = 4e-11 Identities = 45/155 (29%), Positives = 80/155 (51%), Gaps = 12/155 (7%) Query: 12 RVIFVIGKGGVGKTTSSASISVALAKAGYRTLIVSLDPAHNLGDVF-MEKLSDKPR---- 66 RV+ G GGVGKTT++A++++ A+ G +++++DPA L + L + P+ Sbjct: 20 RVVVCCGAGGVGKTTTAAALALRAAEYGRTVVVLTIDPAKRLAQALGINDLGNTPQRVPL 79 Query: 67 --EIIDNLYASELDMEGMIKGYLEHLEKNLKNMYRYLTVINLEKYFEVLRYSPGIEEYAT 124 E+ L+A LDM + + + R ++++ + Y V G +EY Sbjct: 80 APEVPGELHAMMLDM----RRTFDEMVMQYSGPERAQSILDNQFYQTVATSLAGTQEYMA 135 Query: 125 LEAIREILVKGDEWDVIVFDTPPTGLTLRVLALPR 159 +E + ++L + D WD+IV DTPP+ L L P+ Sbjct: 136 MEKLGQLLSQ-DRWDLIVVDTPPSRNALDFLDAPK 169 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.319 0.139 0.388 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 117811944 Number of Sequences: 2977 Number of extensions: 4911432 Number of successful extensions: 20304 Number of sequences better than 1.0e-10: 33 Number of HSP's better than 0.0 without gapping: 6 Number of HSP's successfully gapped in prelim test: 27 Number of HSP's that attempted gapping in prelim test: 20216 Number of HSP's gapped (non-prelim): 49 length of query: 330 length of database: 189,106,746 effective HSP length: 58 effective length of query: 272 effective length of database: 154,394,500 effective search space: 41995304000 effective search space used: 41995304000 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.7 bits) S2: 165 (68.7 bits)