BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1559 (hypD) DE:hydrogenase expression/formation protein
(hypD)
         (367 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||E75031 hydrogenase expression/formation protein (hypd) PAB1...   760  0.0
pir||G71076 probable hydrogenase expression/formation protein hy...   668  0.0
sp|Q58400|Y993_METJA PUTATIVE HYDROGENASE EXPRESSION/FORMATION P...   333  1e-90
gi|11498966 hydrogenase expression/formation protein (hypD) [Arc...   330  1e-89
pir||D69009 hydrogenase expression/formation protein HypD - Meth...   322  4e-87
pir||F70399 hydrogenase expression/formation protein HypD - Aqui...   289  3e-77
sp|P31903|HYPD_ALCEU HYDROGENASE EXPRESSION/FORMATION PROTEIN HY...   284  9e-76
sp|P42033|HUPD_AZOCH HYDROGENASE EXPRESSION/FORMATION PROTEIN HU...   279  3e-74
sp|P31882|HYPD_AZOVI HYDROGENASE EXPRESSION/FORMATION PROTEIN HY...   277  2e-73
pir||H81410 hydrogenase isoenzymes formation protein Cj0625 [imp...   273  3e-72
sp|P40598|HYPD_RHILV HYDROGENASE EXPRESSION/FORMATION PROTEIN HY...   272  5e-72
sp|P31904|HYPD_BRAJA HYDROGENASE EXPRESSION/FORMATION PROTEIN HY...   271  1e-71
pir||S74470 hydrogenase isoenzymes formation protein hypD - Syne...   262  4e-69
pir||B64632 hydrogenase expression/formation protein - Helicobac...   261  7e-69
pir||F71883 hydrogenase expression/formation protein - Helicobac...   259  5e-68
gb|AAA69239.1| (U29579) CG Site no. 33116; ORF_o373 [Escherichia...   243  2e-63
sp|P24192|HYPD_ECOLI HYDROGENASE ISOENZYMES FORMATION PROTEIN HY...   243  3e-63
pir||S59984 hypD protein - Rhodobacter capsulatus >gi|46055|emb|...   236  2e-61
sp|P26411|HYPD_RHOCA HYDROGENASE EXPRESSION/FORMATION PROTEIN HY...   236  2e-61
gb|AAB64435.1| (AF006594) HupD [Anabaena PCC7120]                     146  4e-34
gb|AAF20001.1|AF214145_8 (AF214145) hydrogenase maturating prote...    69  6e-11

>pir||E75031 hydrogenase expression/formation protein (hypd) PAB1559 -
           Pyrococcus abyssi (strain Orsay)
           >gi|5458659|emb|CAB50146.1| (AJ248287) hydrogenase
           expression/formation protein (hypD) [Pyrococcus abyssi]
           Length = 367
           
 Score =  760 bits (1940), Expect = 0.0
 Identities = 367/367 (100%), Positives = 367/367 (100%)

Query: 1   MLEKFRDKEIAQKIVRKIHKEAKGFDELRFMHVCGTHEDTVTRAGIRSLLPENVKIMSGP 60
           MLEKFRDKEIAQKIVRKIHKEAKGFDELRFMHVCGTHEDTVTRAGIRSLLPENVKIMSGP
Sbjct: 1   MLEKFRDKEIAQKIVRKIHKEAKGFDELRFMHVCGTHEDTVTRAGIRSLLPENVKIMSGP 60

Query: 61  GCPVCITPVEDIVRMMEIMRKAKEEGEDIILTTFGDMYRIPTPMGSFADLKSEGFDVRVV 120
           GCPVCITPVEDIVRMMEIMRKAKEEGEDIILTTFGDMYRIPTPMGSFADLKSEGFDVRVV
Sbjct: 61  GCPVCITPVEDIVRMMEIMRKAKEEGEDIILTTFGDMYRIPTPMGSFADLKSEGFDVRVV 120

Query: 121 YSIYDSYKIAQENRDKLVVHFSPGFETTTAPTAGMLETVINEGLDNFKIYSVHRLTPPAV 180
           YSIYDSYKIAQENRDKLVVHFSPGFETTTAPTAGMLETVINEGLDNFKIYSVHRLTPPAV
Sbjct: 121 YSIYDSYKIAQENRDKLVVHFSPGFETTTAPTAGMLETVINEGLDNFKIYSVHRLTPPAV 180

Query: 181 EALLKAGTVFHGLIDPGHVSTIIGVRGWAYLTEKYNIPQVVAGFEPVDVLLGILILIRMV 240
           EALLKAGTVFHGLIDPGHVSTIIGVRGWAYLTEKYNIPQVVAGFEPVDVLLGILILIRMV
Sbjct: 181 EALLKAGTVFHGLIDPGHVSTIIGVRGWAYLTEKYNIPQVVAGFEPVDVLLGILILIRMV 240

Query: 241 KEGEAKIINEYSRVVKWEGNVKAQELINKFFEVKDAKWRALGIIPQSGLELKREWKDLEI 300
           KEGEAKIINEYSRVVKWEGNVKAQELINKFFEVKDAKWRALGIIPQSGLELKREWKDLEI
Sbjct: 241 KEGEAKIINEYSRVVKWEGNVKAQELINKFFEVKDAKWRALGIIPQSGLELKREWKDLEI 300

Query: 301 RTLYNPDVPKLPDLEKGCLCGAILRGLALPPQCPHFGKTCTPRHPIGPCMVSYEGTCSIF 360
           RTLYNPDVPKLPDLEKGCLCGAILRGLALPPQCPHFGKTCTPRHPIGPCMVSYEGTCSIF
Sbjct: 301 RTLYNPDVPKLPDLEKGCLCGAILRGLALPPQCPHFGKTCTPRHPIGPCMVSYEGTCSIF 360

Query: 361 YKYGALF 367
           YKYGALF
Sbjct: 361 YKYGALF 367


>pir||G71076 probable hydrogenase expression/formation protein hypD - Pyrococcus
           horikoshii >gi|3257290|dbj|BAA29973.1| (AP000004) 367aa
           long hypothetical hydrogenase expression/formation
           protein hypD [Pyrococcus horikoshii]
           Length = 367
           
 Score =  668 bits (1705), Expect = 0.0
 Identities = 311/367 (84%), Positives = 344/367 (92%)

Query: 1   MLEKFRDKEIAQKIVRKIHKEAKGFDELRFMHVCGTHEDTVTRAGIRSLLPENVKIMSGP 60
           MLEKFR++ +AQ+I+ KI +E KG +E+RFMHVCGTHEDTVTR+GIRSLLP+NVKIMSGP
Sbjct: 1   MLEKFRERAVAQRIIEKIKEEVKGMEEVRFMHVCGTHEDTVTRSGIRSLLPKNVKIMSGP 60

Query: 61  GCPVCITPVEDIVRMMEIMRKAKEEGEDIILTTFGDMYRIPTPMGSFADLKSEGFDVRVV 120
           GCPVCITPVEDIV+MMEIM+ A+EEGE+IILTTFGDMY+IPTP GSFADLKS+G+DVR+V
Sbjct: 61  GCPVCITPVEDIVKMMEIMKIAREEGEEIILTTFGDMYKIPTPRGSFADLKSQGYDVRIV 120

Query: 121 YSIYDSYKIAQENRDKLVVHFSPGFETTTAPTAGMLETVINEGLDNFKIYSVHRLTPPAV 180
           YSIYDSYKIA+EN DKLVVHFSPGFETTTAPTAGMLE V+ EGL+NF+IYSVHRLTPPAV
Sbjct: 121 YSIYDSYKIAKENPDKLVVHFSPGFETTTAPTAGMLEVVVEEGLENFRIYSVHRLTPPAV 180

Query: 181 EALLKAGTVFHGLIDPGHVSTIIGVRGWAYLTEKYNIPQVVAGFEPVDVLLGILILIRMV 240
           EALLKAGTVF GLI PGHVSTIIGV+GW YLTEK+ IPQVVAGFEPVDVLL IL LIR+V
Sbjct: 181 EALLKAGTVFQGLITPGHVSTIIGVKGWVYLTEKFGIPQVVAGFEPVDVLLAILTLIRLV 240

Query: 241 KEGEAKIINEYSRVVKWEGNVKAQELINKFFEVKDAKWRALGIIPQSGLELKREWKDLEI 300
           K GEAKI+NEY+R VKWEGNVKAQELI KFFEVKDAKWRALGIIP+SGLEL++EWK+LEI
Sbjct: 241 KRGEAKIVNEYNRAVKWEGNVKAQELIRKFFEVKDAKWRALGIIPKSGLELRKEWKELEI 300

Query: 301 RTLYNPDVPKLPDLEKGCLCGAILRGLALPPQCPHFGKTCTPRHPIGPCMVSYEGTCSIF 360
           R  Y+PDVPKLPDLEKGCLCGA+LRGLALP QCPHFGKTCTPRHPIGPCMVSYEGTC IF
Sbjct: 301 RNYYDPDVPKLPDLEKGCLCGAVLRGLALPTQCPHFGKTCTPRHPIGPCMVSYEGTCHIF 360

Query: 361 YKYGALF 367
           YKYGALF
Sbjct: 361 YKYGALF 367


>sp|Q58400|Y993_METJA PUTATIVE HYDROGENASE EXPRESSION/FORMATION PROTEIN MJ0993
           >gi|2127979|pir||A64424 hydrogenase expression/formation
           protein D - Methanococcus jannaschii
           >gi|1591656|gb|AAB98998.1| (U67542) hydrogenase
           expression/formation protein (hypD) [Methanococcus
           jannaschii]
           Length = 358
           
 Score =  333 bits (846), Expect = 1e-90
 Identities = 164/358 (45%), Positives = 232/358 (63%), Gaps = 9/358 (2%)

Query: 7   DKEIAQKIVRKIHKEAKGFDELRFMHVCGTHEDTVTRAGIRSLLPENVKIMSGPGCPVCI 66
           D+ + +K + KI+K A+  D+L+ MHVCG+HE T+ + GIR +LPEN+ ++ GPGCPVC+
Sbjct: 6   DRALIKKAIDKINKLAEKIDKLKIMHVCGSHEHTICKYGIRDVLPENITVVPGPGCPVCV 65

Query: 67  TPVEDIVRMMEIMRKAKEEGEDIILTTFGDMYRIPTPMGSFADLKSEGFDVRVVYSIYDS 126
           T  ++I   + +           ++TT GDMYR+P    S  + +SEG DVR+VYSI ++
Sbjct: 66  TTQKEIDTAIYLADNG------YVITTLGDMYRVPGSEKSLMEKQSEGCDVRIVYSISEA 119

Query: 127 YKIAQENRDKLVVHFSPGFETTTAPTAGMLETVINEGLDNFKIYSVHRLTPPAVEALLKA 186
            K+A++ RDK  V  + GFETT   T   L ++ N+ ++NF I + HR TPP +E LL  
Sbjct: 120 VKMAKKERDKKFVFVAIGFETTAPTTGAELISLKNKDVNNFFILNCHRQTPPVMEFLLNE 179

Query: 187 GTVFHGLIDPGHVSTIIGVRGWAYLTEKYNIPQVVAGFEPVDVLLGILILIRMVKEGEAK 246
           G      I PGHVSTI G++ +  L EKY  P VVAGFEP+DVL+ I+++++ V  GEAK
Sbjct: 180 GVYLDAFICPGHVSTITGLKPYYGLCEKYKAPMVVAGFEPIDVLMAIIMILKQVISGEAK 239

Query: 247 IINEYSRVVKWEGNVKAQELINKFFEVKDAKWRALGIIPQSGLELKREWKDLEIRTLYNP 306
           + NEY R VK EGNV AQ++IN+ FE  D  WR   ++   G  L+ ++K  +I    + 
Sbjct: 240 VENEYIRAVKPEGNVLAQKIINEVFESIDVPWRGFPVVKNGGFGLREKYKKFDI--YEHE 297

Query: 307 DVPKLPD-LEKGCLCGAILRGLALPPQCPHFGKTCTPRHPIGPCMVSYEGTCSIFYKY 363
           D+P++ + + KGC+C  ILRG  LP  CP FG  CTP +P+G CMVS EGTC IFYKY
Sbjct: 298 DIPEIKEKIPKGCICDKILRGEKLPTDCPLFGTVCTPLNPVGSCMVSDEGTCRIFYKY 355


>gi|11498966 hydrogenase expression/formation protein (hypD) [Archaeoglobus
           fulgidus] >gi|7447453|pir||A69421 hydrogenase
           expression/formation protein (hypD) homolog -
           Archaeoglobus fulgidus >gi|2649201|gb|AAB89873.1|
           (AE001009) hydrogenase expression/formation protein
           (hypD) [Archaeoglobus fulgidus]
           Length = 371
           
 Score =  330 bits (838), Expect = 1e-89
 Identities = 167/356 (46%), Positives = 236/356 (65%), Gaps = 15/356 (4%)

Query: 13  KIVRKIHKEAKGFDELRFMHVCGTHEDTVTRAGIRSLLPENVKIMSGPGCPVCITPVEDI 72
           ++  KI + +K F+ ++ MH+CGTHEDT+T+  +RSLLPEN+ ++SGPGCPVCITP EDI
Sbjct: 22  RLSEKIRELSKEFESVKIMHLCGTHEDTITKYNLRSLLPENISLLSGPGCPVCITPDEDI 81

Query: 73  VRMMEIMRKAKEEGEDIILTTFGDMYRIPTPMGSFADLKSEGFDVRVVYSIYDSYKIAQE 132
             +M ++ K     E+I L TFGDM R+P    S   L++EG+D+R+VYSI+DS K+A E
Sbjct: 82  QMVMHLLEK-----ENITLATFGDMARVPFQGKSLFTLRAEGYDIRIVYSIFDSLKLA-E 135

Query: 133 NRDKLVVHFSPGFETTTAPTAGMLETVINEGLDNFKIYSVHRLTPPAVEALLKAGTVFHG 192
           + D+ VVHF+ GFETT   TA      + +  +NF ++S HR   PAV AL +  TV   
Sbjct: 136 SSDRPVVHFAIGFETTMPSTA----IALLDEKENFYVFSAHRFFIPAVHALCENTTV-DA 190

Query: 193 LIDPGHVSTIIGVRGWAYLTEKYNIPQVVAGFEPVDVLLGILILIRMVKEGEAKIINEYS 252
            I+PGHVSTIIGV+ +  + +KY IPQV+AGFEP DV+L I +L+  + +G  ++INEYS
Sbjct: 191 FINPGHVSTIIGVKPYREILKKYGIPQVIAGFEPEDVMLAIYLLLEAMSDGRREVINEYS 250

Query: 253 RVVKWEGNVKAQELINKFFEVKDAKWRALGIIPQSGLELKREWKDLEIRTLYN---PDVP 309
           R VK EGNV+A E +++ F  +D  WR LG++  SG  L + ++  + R ++     D  
Sbjct: 251 RAVKEEGNVRALEAMDRVFRKEDWSWRGLGVVKGSGGALAKRFEQFDARKVFEDAFADFQ 310

Query: 310 KLPDLEKG-CLCGAILRGLALPPQCPHFGKTCTPRHPIGPCMVSYEGTCSIFYKYG 364
            + D  K  C CG +L+G+A P  CP F K C PR+P+G CMVS EGTC+I+   G
Sbjct: 311 PVEDKSKRLCRCGDVLKGIATPKDCPLFMKACNPRNPVGACMVSVEGTCNIWATSG 366


>pir||D69009 hydrogenase expression/formation protein HypD - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622170|gb|AAB85561.1| (AE000877) hydrogenase
           expression/formation protein HypD [Methanobacterium
           thermoautotrophicum]
           Length = 348
           
 Score =  322 bits (817), Expect = 4e-87
 Identities = 153/359 (42%), Positives = 241/359 (66%), Gaps = 14/359 (3%)

Query: 8   KEIAQKIVRKIHKEAKGFDELRFMHVCGTHEDTVTRAGIRSLLPENVKIMSGPGCPVCIT 67
           K +++++V +I + ++    ++ MHVCG+HE T+ + G+RSLLPE V++++GPGCPVC  
Sbjct: 2   KNLSRELVSRIQEISR---PVKIMHVCGSHEHTIMQHGVRSLLPEEVEVVAGPGCPVCCV 58

Query: 68  PVEDIVRMMEIMRKAKEEGEDIILTTFGDMYRIPTPMGSFADLKSEGFDVRVVYSIYDSY 127
           P  +I   +E+ R+       + +TTFGDM R+P   GS AD +++G DVR+VY + ++ 
Sbjct: 59  PAREIDECIELARQG------VTITTFGDMLRVPGSRGSLADARADGADVRIVYGVGNAV 112

Query: 128 KIAQENRDKLVVHFSPGFETTTAPTAGMLETVINEGLDNFKIYSVHRLTPPAVEALLKAG 187
           +IA++  D+ VV  + GFETT   TA     +++   +NF + S HRL PPA+  L+++G
Sbjct: 113 EIARK-LDREVVFMAAGFETTAPTTAS---EILSGPPENFSVLSCHRLIPPALRFLIESG 168

Query: 188 TV-FHGLIDPGHVSTIIGVRGWAYLTEKYNIPQVVAGFEPVDVLLGILILIRMVKEGEAK 246
            V  + LI+PGHVSTIIG++ +   +  YNIPQV+AGF P+D+L+ + +++R +  GEAK
Sbjct: 169 EVNLNALIEPGHVSTIIGMKPYEPFSRDYNIPQVIAGFNPLDILMAVYMILRQIDRGEAK 228

Query: 247 IINEYSRVVKWEGNVKAQELINKFFEVKDAKWRALGIIPQSGLELKREWKDLEIRTLYNP 306
           + NEY R VK EGN+KAQ+++++ F+V + +WR   +IP+S  E++ E+ +   R  ++ 
Sbjct: 229 VENEYKRAVKPEGNLKAQKVMDEVFKVTEREWRGFPVIPESVYEIRDEFSEFNAREKFDI 288

Query: 307 DVPKLPDLEKGCLCGAILRGLALPPQCPHFGKTCTPRHPIGPCMVSYEGTCSIFYKYGA 365
           +V    D   GC+CGA+LRG+A P +C  F   CTP  PIG CMVS EGTC+I Y+Y +
Sbjct: 289 EVEDTVDTPAGCICGAVLRGVARPEECKLFKNECTPTSPIGACMVSREGTCNIAYRYSS 347


>pir||F70399 hydrogenase expression/formation protein HypD - Aquifex aeolicus
           >gi|2983616|gb|AAC07185.1| (AE000726) hydrogenase
           expression/formation protein HypD [Aquifex aeolicus]
           Length = 380
           
 Score =  289 bits (732), Expect = 3e-77
 Identities = 141/373 (37%), Positives = 232/373 (61%), Gaps = 16/373 (4%)

Query: 1   MLEKFRDKEIAQKIVRKIHKEAKGFDE-LRFMHVCGTHEDTVTRAGIRSLLPENVKIMSG 59
           + E ++DKE   K+  KI K ++     +  M  CG H   + + GI  LL   V+ + G
Sbjct: 8   IFEAYKDKERVLKLSEKIKKLSEKIGRTVNIMEFCGGHTHAIMKYGIDQLLKGVVRFIHG 67

Query: 60  PGCPVCITPVEDIVRMMEIMRKAKEEGEDIILTTFGDMYRIP-TPMGSFADLKSEGFDVR 118
           PGCPVC+ P++ I   +E+ ++     +D+I+ ++GD+ R+P +   S  ++++EG DVR
Sbjct: 68  PGCPVCVMPMQRIDLAIELAKR-----KDVIMCSYGDLLRVPGSKRKSLLNVRAEGADVR 122

Query: 119 VVYSIYDSYKIAQENRDKLVVHFSPGFETTTAPTAGMLETVINEGLDNFKIYSVHRLTPP 178
           +VYS  D+ KIA+EN DK V+ F+ GFETTT  TA +++    EG+ N  + S H +TP 
Sbjct: 123 MVYSCLDTLKIAKENPDKKVIFFAIGFETTTPQTAVLIKKAKEEGIKNLFVVSNHVITPA 182

Query: 179 AVEALLKAGTV-------FHGLIDPGHVSTIIGVRGWAYLTEKYNIPQVVAGFEPVDVLL 231
           A++ +L A  +           I PGHVS IIG + + Y  E++  P V+AGFEP++VL 
Sbjct: 183 AIQHILNAPEIREIGKVEIDAFIGPGHVSVIIGTKPYHYFAEEFQKPVVIAGFEPLNVLK 242

Query: 232 GILILIRMVKEGEAKIINEYSRVVKWEGNVKAQELINKFFEV-KDAKWRALGIIPQSGLE 290
            + ++++ + +G A++ N Y+R V ++GN+KAQ L+ + FE+ K+ +WR LG IP S L+
Sbjct: 243 AVYLILKQIYKGRAEVKNNYTRFVTYKGNLKAQNLVAELFELRKEFEWRGLGTIPYSALK 302

Query: 291 LKREWKDLEIRTLYNPDVPKLPDLEKGCLCGAILRGLALPPQCPHFGKTCTPRHPIGPCM 350
           +++E+++ +   ++  ++P+ P     C+CG ++RG+A P  C  FG  CTP +P+G CM
Sbjct: 303 IRKEYEEFDAEKVFEVELPE-PKEHPACICGKVIRGVARPTDCKLFGTVCTPSNPLGSCM 361

Query: 351 VSYEGTCSIFYKY 363
           VS EG C+ +YKY
Sbjct: 362 VSSEGACAAYYKY 374


>sp|P31903|HYPD_ALCEU HYDROGENASE EXPRESSION/FORMATION PROTEIN HYPD
           >gi|321749|pir||S29978 hypD protein - Alcaligenes
           eutrophus >gi|38775|emb|CAA49734.1| (X70183) HYPD
           [Ralstonia eutropha]
           Length = 379
           
 Score =  284 bits (720), Expect = 9e-76
 Identities = 147/372 (39%), Positives = 218/372 (58%), Gaps = 15/372 (4%)

Query: 2   LEKFRDKEIAQKIVRKIHKEAKGFDELRFMHVCGTHEDTVTRAGIRSLLPENVKIMSGPG 61
           +E+FRD E+AQ+I   +  EA+      FM  CG H   ++R G+  LLPENV+++ GPG
Sbjct: 4   IEEFRDGELAQRIAAHVRAEARPGQRYNFMEFCGGHTHAISRYGVTELLPENVRMIHGPG 63

Query: 62  CPVCITPVEDIVRMMEIMRKAKEEGEDIILTTFGDMYRIPTPMG-SFADLKSEGFDVRVV 120
           CPVC+ P+  I   + +  +      D I+ T+GD  R+P   G S    K+ G D+R+V
Sbjct: 64  CPVCVLPIGRIDLALHLALE-----RDAIVCTYGDTMRVPASGGMSLIRAKAHGADIRMV 118

Query: 121 YSIYDSYKIAQENRDKLVVHFSPGFETTTAPTAGMLETVINEGLDNFKIYSVHRLTPPAV 180
           YS  D+ KIAQ +  + VV  + GFETTT PTA ++       +DNF +   H LTP A+
Sbjct: 119 YSAADALKIAQRHPQREVVFLAIGFETTTPPTALIIREAKARQVDNFSVLCCHVLTPSAI 178

Query: 181 EALLKA------GTV-FHGLIDPGHVSTIIGVRGWAYLTEKYNIPQVVAGFEPVDVLLGI 233
             +L++      GTV   G + P HVS +IG R + + + +Y  P V+AGFEP+DV+  I
Sbjct: 179 THILESPEVRDYGTVPIDGFVGPAHVSIVIGTRPYEHFSREYGKPVVIAGFEPLDVMQAI 238

Query: 234 LILIRMVKEGEAKIINEYSRVVKWEGNVKAQELINKFFEVKDA-KWRALGIIPQSGLELK 292
           L+L+R V  G A++ NE+ R V  +GN  AQ ++++ FE++ + +WR LG +P S L ++
Sbjct: 239 LMLVRQVNSGRAEVENEFVRAVTRDGNESAQAMVSEVFELRPSFEWRGLGEVPYSALRIR 298

Query: 293 REWKDLEIRTLYNPDVPKLPDLEKGCLCGAILRGLALPPQCPHFGKTCTPRHPIGPCMVS 352
            ++   +    ++     +PD  K C CGAILRG+  P  C  F   CTP +P+G CMVS
Sbjct: 299 AQFARFDAEQRFDLRYRPVPD-NKACECGAILRGVKKPTDCKLFATVCTPENPMGSCMVS 357

Query: 353 YEGTCSIFYKYG 364
            EG C+  Y YG
Sbjct: 358 SEGACAAHYSYG 369


>sp|P42033|HUPD_AZOCH HYDROGENASE EXPRESSION/FORMATION PROTEIN HUPD
           >gi|2120752|pir||I39743 hydrogenase homolog 1 -
           Azotobacter chroococcum >gi|142321|gb|AAA22136.1|
           (M92282) hydrogenase-related protein [Azotobacter
           chroococcum] >gi|382215|prf||1819270A hydrogenase
           [Azotobacter chroococcum]
           Length = 379
           
 Score =  279 bits (707), Expect = 3e-74
 Identities = 148/371 (39%), Positives = 223/371 (59%), Gaps = 14/371 (3%)

Query: 2   LEKFRDKEIAQKIVRKIHKEAKGFDELRFMHVCGTHEDTVTRAGIRSLLPENVKIMSGPG 61
           +++FRD   A+++  +I  EA    + R M  CG H   + R GI  LLP +V+++ GPG
Sbjct: 4   VDEFRDGATARQLAARIAAEADPARQYRLMEFCGGHTHAIFRYGIPDLLPASVRLIHGPG 63

Query: 62  CPVCITPVEDIVRMMEIMRKAKEEGEDIILTTFGDMYRIPTP-MGSFADLKSEGFDVRVV 120
           CPVC+ P+  +   +E+ R+      ++IL T+GDM R+P     S    ++E   VR++
Sbjct: 64  CPVCVMPIGRLDMAIELARRP-----EVILCTYGDMLRVPASGRVSLLKARAESAAVRML 118

Query: 121 YSIYDSYKIAQENRDKLVVHFSPGFETTTAPTAGMLETVINEGLDNFKIYSVHRLTPPAV 180
           YS  ++ K+AQ+N  K VV F+ GFETTT PTA ++E     GL NF ++  H LTP A+
Sbjct: 119 YSPAEALKLAQDNPSKEVVFFAIGFETTTPPTALVIEQAQRLGLKNFSVFCNHVLTPAAM 178

Query: 181 EALL-----KAGTV-FHGLIDPGHVSTIIGVRGWAYLTEKYNIPQVVAGFEPVDVLLGIL 234
            A+L     +AGT+   G I P HVST+IG   +A   ++Y  P V+AGFEP+D+L  +L
Sbjct: 179 HAILATPEARAGTLQLDGFIGPAHVSTVIGSAPYAPFPQQYGTPLVIAGFEPLDLLQALL 238

Query: 235 ILIRMVKEGEAKIINEYSRVVKWEGNVKAQELINKFFEVKDA-KWRALGIIPQSGLELKR 293
           +L+R + EG A++ N+++R V  EGN KA+ L  + FEV+++ +WR LG +P S L+++ 
Sbjct: 239 MLVRQLNEGRAEVENQFTRAVTAEGNRKAKALTERVFEVRESFEWRGLGAVPHSALQIRE 298

Query: 294 EWKDLEIRTLYNPDVPKLPDLEKGCLCGAILRGLALPPQCPHFGKTCTPRHPIGPCMVSY 353
            + +      +  + P+     K C C AILRG   P  C  FG  CTP +P+G CMVS 
Sbjct: 299 AFAEFNAERRFALE-PRTGLENKACECPAILRGAKSPRDCKLFGNPCTPDNPLGSCMVSS 357

Query: 354 EGTCSIFYKYG 364
           EG C+ +Y YG
Sbjct: 358 EGACAAWYAYG 368


>sp|P31882|HYPD_AZOVI HYDROGENASE EXPRESSION/FORMATION PROTEIN HYPD >gi|95053|pir||S23443
           hypothetical protein 8 - Azotobacter vinelandii
           >gi|39245|emb|CAA45187.1| (X63650) ORF8 [Azotobacter
           vinelandii] >gi|398011|gb|AAA19512.1| (L23970) hypD
           [Azotobacter vinelandii]
           Length = 379
           
 Score =  277 bits (700), Expect = 2e-73
 Identities = 146/371 (39%), Positives = 222/371 (59%), Gaps = 14/371 (3%)

Query: 2   LEKFRDKEIAQKIVRKIHKEAKGFDELRFMHVCGTHEDTVTRAGIRSLLPENVKIMSGPG 61
           +++FRD   A+++  +I  EA    + R M  CG H   + R GI  LLP NV+++ GPG
Sbjct: 4   VDEFRDGATARQLAARIAAEADPKRQYRLMEFCGGHTHAIFRYGIPDLLPANVRLIHGPG 63

Query: 62  CPVCITPVEDIVRMMEIMRKAKEEGEDIILTTFGDMYRIPTP-MGSFADLKSEGFDVRVV 120
           CPVC+ P+  +   +E+ R+       +IL T+GDM R+P     S    ++EG  VR++
Sbjct: 64  CPVCVMPIGRLDMAIELARRP-----GVILCTYGDMLRVPASGRVSLLKARAEGAAVRML 118

Query: 121 YSIYDSYKIAQENRDKLVVHFSPGFETTTAPTAGMLETVINEGLDNFKIYSVHRLTPPAV 180
           YS  ++ K+AQ+N D+ VV F+ GFETTT PTA ++E     GL NF ++  H LTP A+
Sbjct: 119 YSPIEALKLAQDNPDRDVVFFAIGFETTTPPTALVIEQAQRLGLKNFSVFCNHVLTPAAM 178

Query: 181 EALL-----KAGTV-FHGLIDPGHVSTIIGVRGWAYLTEKYNIPQVVAGFEPVDVLLGIL 234
            A+L     +AGT+   G I P HVST+IG   +A    +Y  P V+AGFEP+D+L  +L
Sbjct: 179 HAILATPEARAGTLQLDGFIGPAHVSTVIGSDAYAPFPRQYGTPLVIAGFEPLDLLQALL 238

Query: 235 ILIRMVKEGEAKIINEYSRVVKWEGNVKAQELINKFFEVKDA-KWRALGIIPQSGLELKR 293
           +L+R + EG A++ N+++R V   GN+KA+ L  + FE++++ +WR LG +P S L ++ 
Sbjct: 239 MLVRQLNEGRAEVENQFTRAVTAGGNLKAKALTGRIFELRESFEWRGLGALPNSALRIRE 298

Query: 294 EWKDLEIRTLYNPDVPKLPDLEKGCLCGAILRGLALPPQCPHFGKTCTPRHPIGPCMVSY 353
            + + +    +  +     +  K C C AILRG   P  C  FG  C+P +P+G CMVS 
Sbjct: 299 AFAEFDAERRFALEARSGLE-NKACECPAILRGAKSPRDCKLFGNPCSPDNPLGSCMVSS 357

Query: 354 EGTCSIFYKYG 364
           EG C+ +Y YG
Sbjct: 358 EGACAAWYAYG 368


>pir||H81410 hydrogenase isoenzymes formation protein Cj0625 [imported] -
           Campylobacter jejuni (strain NCTC 11168)
           >gi|6968092|emb|CAB75261.1| (AL139075) hydrogenase
           isoenzymes formation protein [Campylobacter jejuni]
           Length = 363
           
 Score =  273 bits (690), Expect = 3e-72
 Identities = 146/363 (40%), Positives = 214/363 (58%), Gaps = 9/363 (2%)

Query: 2   LEKFRDKEIAQKIVRKIHKEAKGFDELRFMHVCGTHEDTVTRAGIRSLLPENVKIMSGPG 61
           +++FRDKE    + + I +E K  + +  M +CG H  ++ +  + S+LP+ +  + GPG
Sbjct: 4   IDEFRDKESILALKKLIEQELK--NPINIMEICGGHTHSIMKYALPSILPKEINFIHGPG 61

Query: 62  CPVCITPVEDIVRMMEIMRKAKEEGEDIILTTFGDMYRIPTPMGSFADLKSEGFDVRVVY 121
           CPVC+ P    VR+   ++ A  +  D I  T GD+ R+P    S  DL+++G DVR +Y
Sbjct: 62  CPVCVMPR---VRIDTAIKLASMK--DTIFCTLGDLLRVPGSEISLLDLRAKGADVRALY 116

Query: 122 SIYDSYKIAQENRDKLVVHFSPGFETTTAPTAGMLETVINEGLDNFKIYSVHRLTPPAVE 181
           S  +  +IA++N +K ++ F+ GFETTT  +A +L+ VI E ++N   +  H   P  VE
Sbjct: 117 SPLEVLEIAKQNLNKNIIFFAIGFETTTPMSALLLQKVIEEKINNVFFHINHITVPAPVE 176

Query: 182 ALLKAGTV-FHGLIDPGHVSTIIGVRGWAYLTEKYNIPQVVAGFEPVDVLLGILILIRMV 240
           A++    V  +  + P HVS I G   +  L  K+  P  V+GFEPVD+L  +L +I+  
Sbjct: 177 AIMNDENVKINAFLGPSHVSVITGYGIYEPLAAKFKTPIAVSGFEPVDILESVLNIIKQS 236

Query: 241 KEGEAKIINEYSRVVKWEGNVKAQELINKFFEVKDAKWRALGIIPQSGLELKREWKDLEI 300
            EG  K+ N+Y R V  EGNVKAQ L+ K+F V D ++R LG+I   GLELK E+   + 
Sbjct: 237 NEGTFKVYNQYKRAVSKEGNVKAQNLVKKYFRVCDFEFRGLGLIKDGGLELKEEFSAYDA 296

Query: 301 RTLYNPDVPKLPDLEKGCLCGAILRGLALPPQCPHFGKTCTPRHPIGPCMVSYEGTCSIF 360
              ++  V    +  K C+CG ILRGLA P  C  FGK CTPR PIG CMVS EG C+ +
Sbjct: 297 SKKFDCTVQSKNE-SKACICGQILRGLAKPYDCKVFGKACTPRSPIGSCMVSGEGACAAY 355

Query: 361 YKY 363
           YKY
Sbjct: 356 YKY 358


>sp|P40598|HYPD_RHILV HYDROGENASE EXPRESSION/FORMATION PROTEIN HYPD
           >gi|420900|pir||S32877 hypD protein - Rhizobium
           leguminosarum bv. viciae >gi|48736|emb|CAA37163.1|
           (X52974) hypD [Rhizobium leguminosarum]
           Length = 385
           
 Score =  272 bits (688), Expect = 5e-72
 Identities = 146/372 (39%), Positives = 212/372 (56%), Gaps = 15/372 (4%)

Query: 2   LEKFRDKEIAQKIVRKIHKEAKGFDELRFMHVCGTHEDTVTRAGIRSLLPENVKIMSGPG 61
           ++++RD  +A+ + R+I   A       FM  CG H   ++R G+  LLP NV+++ GPG
Sbjct: 4   IDEYRDGSLAKDVARQITALADPARSYHFMEFCGGHTHAISRYGLEDLLPANVRMIHGPG 63

Query: 62  CPVCITPVEDIVRMMEIMRKAKEEGEDIILTTFGDMYRIPTPMGS-FADLKSEGFDVRVV 120
           CPVC+ P+  I   + +  +      +I L T+GD+ R+P   GS     K+ G D+R+V
Sbjct: 64  CPVCVLPIGRIDAAIALAMRP-----EITLCTYGDLMRVPGSNGSSLLKAKAAGADIRMV 118

Query: 121 YSIYDSYKIAQENRDKLVVHFSPGFETTTAPTAGMLETVINEGLDNFKIYSVHRLTPPAV 180
           YS  D+ +IA    D+ VV F+ GFETTT  TA  L+  I  GL NF I+  H LTP  +
Sbjct: 119 YSTLDALRIADAEPDREVVFFAIGFETTTPTTALALKAAIARGLGNFSIFCNHVLTPAPI 178

Query: 181 EALL------KAGTV-FHGLIDPGHVSTIIGVRGWAYLTEKYNIPQVVAGFEPVDVLLGI 233
           + +L      K GT+   G I P HVST+IG   + +  E++  P VVAGFEP+DV+  I
Sbjct: 179 QNILESPDVRKLGTIKIDGFIGPAHVSTVIGTEPYEFFAEEFRKPVVVAGFEPLDVIQAI 238

Query: 234 LILIRMVKEGEAKIINEYSRVVKWEGNVKAQELINKFFEVKDA-KWRALGIIPQSGLELK 292
           L+L+R V +G  ++ N+Y R V   GN KAQ  +  FFE++++ +WR LG +P   L L+
Sbjct: 239 LMLVRQVNDGRHEVENQYIRAVTALGNEKAQAEVANFFELRESFEWRGLGEVPYGALRLR 298

Query: 293 REWKDLEIRTLYNPDVPKLPDLEKGCLCGAILRGLALPPQCPHFGKTCTPRHPIGPCMVS 352
            ++   +    ++   P   D    C CGAILRG+  P  C  FG  CTP  P+G CMVS
Sbjct: 299 PQYAAYDAEKRFSMVTPAAKD-NPACECGAILRGVKKPADCKLFGTVCTPDTPMGSCMVS 357

Query: 353 YEGTCSIFYKYG 364
            EG C+  + YG
Sbjct: 358 PEGACAAHWAYG 369


>sp|P31904|HYPD_BRAJA HYDROGENASE EXPRESSION/FORMATION PROTEIN HYPD
           >gi|486752|pir||S35229 hypD' protein - Bradyrhizobium
           japonicum (fragment) >gi|39535|emb|CAA78988.1| (Z17373)
           hypD' [Bradyrhizobium japonicum]
           >gi|448282|prf||1916405A hypD gene [Bradyrhizobium
           japonicum]
           Length = 347
           
 Score =  271 bits (685), Expect = 1e-71
 Identities = 136/340 (40%), Positives = 206/340 (60%), Gaps = 15/340 (4%)

Query: 34  CGTHEDTVTRAGIRSLLPENVKIMSGPGCPVCITPVEDIVRMMEIMRKAKEEGEDIILTT 93
           CG H   ++R G+  +LP NV+++ GPGCPVC+ P   I   + +  +      DIIL  
Sbjct: 3   CGGHTHAISRYGLEDMLPANVRMIHGPGCPVCVLPAGRIDMAIRLAMRP-----DIILCV 57

Query: 94  FGDMYRIPTPMG-SFADLKSEGFDVRVVYSIYDSYKIAQENRDKLVVHFSPGFETTTAPT 152
           +GD+ R+P   G S    K+ G D+R+VYS  D+ +IA++N  + VV F+ GFETTT PT
Sbjct: 58  YGDLMRVPGSQGASLLKAKARGADIRMVYSTIDAIRIAEDNPGREVVFFAIGFETTTPPT 117

Query: 153 AGMLETVINEGLDNFKIYSVHRLTPPAVEALLKAGTV-------FHGLIDPGHVSTIIGV 205
           A M+     + L+NF ++  H LTPPA++ +L++  +         G + P HVSTIIG 
Sbjct: 118 AVMIRLAGKKQLENFSVFCNHVLTPPAMQNILESPDIRNIGRVEIDGFVGPAHVSTIIGT 177

Query: 206 RGWAYLTEKYNIPQVVAGFEPVDVLLGILILIRMVKEGEAKIINEYSRVVKWEGNVKAQE 265
             + +  E++  P V+AGFEP+D++  IL+L+R V E   ++ N+YSR V  +GN++A+E
Sbjct: 178 APYEFFAEEFGKPVVIAGFEPLDMMQAILMLVRQVNEHRHEVENQYSRAVTRDGNLRAKE 237

Query: 266 LINKFFEVKDA-KWRALGIIPQSGLELKREWKDLEIRTLYNPDVPKLPDLEKGCLCGAIL 324
            ++  FE++D  +WR LG +P SGL+LKR +   +    ++ +  ++ D    C CGAIL
Sbjct: 238 EVSDIFELRDQFEWRGLGQVPYSGLKLKRAYAKYDAEVRFDMNELRVDD-NPACECGAIL 296

Query: 325 RGLALPPQCPHFGKTCTPRHPIGPCMVSYEGTCSIFYKYG 364
           RG+  P  C  FG  CTP  P+G CMVS EG C+  + YG
Sbjct: 297 RGVKKPVDCKLFGTVCTPETPMGSCMVSSEGACAAHWTYG 336


>pir||S74470 hydrogenase isoenzymes formation protein hypD - Synechocystis sp.
           (strain PCC 6803) >gi|1651694|dbj|BAA16622.1| (D90899)
           hydrogenase isoenzymes formation protein HypD
           [Synechocystis sp.]
           Length = 374
           
 Score =  262 bits (663), Expect = 4e-69
 Identities = 140/371 (37%), Positives = 211/371 (56%), Gaps = 22/371 (5%)

Query: 2   LEKFRDKEIA----QKIVRKIHKEAKGFDELRFMHVCGTHEDTVTRAGIRSLLPENVKIM 57
           ++++RD +      Q I R+I K          M +CG    ++ + G+ +LLP+N+ ++
Sbjct: 4   VDEYRDAQAVAHYRQAIAREITKP------WTLMEICGGQTHSIVKYGLDALLPKNLTLI 57

Query: 58  SGPGCPVCITPVEDIVRMMEIMRKAKEEGEDIILTTFGDMYRIPTPMGSFADLKSEGFDV 117
            GPGCPVC+TP+E I + + + ++      +II  +FGDM R+P        +K++G DV
Sbjct: 58  HGPGCPVCVTPMELIDQALWLAKQP-----EIIFCSFGDMLRVPGSGADLLSIKAQGGDV 112

Query: 118 RVVYSIYDSYKIAQENRDKLVVHFSPGFETTTAPTAGMLETVINEGLDNFKIYSVHRLTP 177
           R+VYS  D   IA+EN ++ VV F  GFETT   TA  L     +G+ NF +   H L P
Sbjct: 113 RIVYSPLDCLAIARENPNREVVFFGVGFETTAPATAMTLHQARAQGISNFSLLCAHVLVP 172

Query: 178 PAVEALL-KAGTVFHGLIDPGHVSTIIGVRGWAYLTEKYNIPQVVAGFEPVDVLLGILIL 236
           PA+EALL    ++  G +  GHV T+ G R + ++ EKY +P V+ GFEPVD++ GI   
Sbjct: 173 PAMEALLGNPNSLVQGFLAAGHVCTVTGERAYQHIAEKYQVPIVITGFEPVDIMQGIFAC 232

Query: 237 IRMVKEGEAKIINEYSRVVKWEGNVKAQELINKFFEVKDAKWRALGIIPQSGLELKREWK 296
           +R ++ G+    N+Y R V+ +GN  AQ++I++ FE  D  WR LG+IP SGL L+  + 
Sbjct: 233 VRQLESGQFTCNNQYRRSVQPQGNAHAQKIIDQVFEPVDRHWRGLGLIPASGLGLRPAFA 292

Query: 297 D----LEIRTLYNPDVPKLPDLEKGCLCGAILRGLALPPQCPHFGKTCTPRHPIGPCMVS 352
                ++   L     P +   E  C+ G IL+G   P  CP FG  CTP  P+G  MVS
Sbjct: 293 PWDAAVKFANLLQTMAPTMG--ETVCISGEILQGQRKPSDCPAFGTICTPEQPLGAPMVS 350

Query: 353 YEGTCSIFYKY 363
            EG C+ +Y+Y
Sbjct: 351 SEGACAAYYRY 361


>pir||B64632 hydrogenase expression/formation protein - Helicobacter pylori
           (strain 26695) >gi|2314033|gb|AAD07944.1| (AE000599)
           hydrogenase expression/formation protein (hypD)
           [Helicobacter pylori 26695]
           Length = 370
           
 Score =  261 bits (661), Expect = 7e-69
 Identities = 141/367 (38%), Positives = 212/367 (57%), Gaps = 9/367 (2%)

Query: 1   MLEKFRDKEIAQKIVRKIHKEAKGFDE-LRFMHVCGTHEDTVTRAGIRSLLPENVKIMSG 59
           ++  FRDK     +   I K A   ++ L  M VCG H  ++ + G+  L+P N++ + G
Sbjct: 6   LISPFRDKRTLLALSNAIKKLAFKLEKKLVIMEVCGGHTHSIMKYGLLDLMPNNLEFVHG 65

Query: 60  PGCPVCITPVEDIVRMMEIMRKAKEEGEDIILTTFGDMYRIPTPMGSFADLKSEGFDVRV 119
           PGCPVC+ P   +    E+        +D I+ + GDM R+P   GS    + +G D R 
Sbjct: 66  PGCPVCVMPRARLDEAYELATI-----KDSIVLSLGDMMRVPGSYGSLIQAREKGLDARF 120

Query: 120 VYSIYDSYKIAQENRDKLVVHFSPGFETTTAPTAGMLETVINEGLDNFKIYSVHRLTPPA 179
           +YS   + +IA+EN  K V++ + GFETTT  +A +L +   E ++N   +  H L PP+
Sbjct: 121 LYSPMQALEIAKENPTKKVIYIAIGFETTTPMSASVLWSAKKEKINNLFFHINHILVPPS 180

Query: 180 VEALLK-AGTVFHGLIDPGHVSTIIGVRGWAYLTEKYNIPQVVAGFEPVDVLLGILILIR 238
           V A+LK      + L+ P HVS I G + +A L +++ IP +V+GFEPVD+L  +L+LI+
Sbjct: 181 VSAILKDPACQINALLAPSHVSVISGAQIYAPLVDRFKIPIIVSGFEPVDILESVLMLIK 240

Query: 239 MVKEGEAKIINEYSRVVKWEGNVKAQELINKFFEVKD-AKWRALGIIPQSGLELKREWKD 297
                EAK+  +Y R V +EGNVKAQEL+N   EV++  +WR LG I +S L+LK  +  
Sbjct: 241 QALNKEAKLEIQYKRAVSFEGNVKAQELVNACMEVRENFEWRGLGNIKRSALKLKEAFAS 300

Query: 298 LEIRTLYNPDVP-KLPDLEKGCLCGAILRGLALPPQCPHFGKTCTPRHPIGPCMVSYEGT 356
            +   ++   +  K     K C CG IL+G+A P  C  F  TCTP++PIG CMVS EG 
Sbjct: 301 YDAEEVFKEYLSHKTSKENKACKCGEILKGIAKPLDCSLFATTCTPQNPIGSCMVSSEGA 360

Query: 357 CSIFYKY 363
           C+ +Y+Y
Sbjct: 361 CAAYYRY 367


>pir||F71883 hydrogenase expression/formation protein - Helicobacter pylori
           (strain J99) >gi|4155404|gb|AAD06413.1| (AE001512)
           Hydrogenase expression/formation protein [Helicobacter
           pylori J99]
           Length = 370
           
 Score =  259 bits (654), Expect = 5e-68
 Identities = 140/367 (38%), Positives = 209/367 (56%), Gaps = 9/367 (2%)

Query: 1   MLEKFRDKEIAQKIVRKIHKEA-KGFDELRFMHVCGTHEDTVTRAGIRSLLPENVKIMSG 59
           ++  FRDK I   +  +I K A K   +L  M VCG H  ++ + G+  L+P+N++   G
Sbjct: 6   LISPFRDKRIILALSNEIKKFASKLTKKLVIMEVCGGHTHSIMKYGLLDLMPKNLEFAHG 65

Query: 60  PGCPVCITPVEDIVRMMEIMRKAKEEGEDIILTTFGDMYRIPTPMGSFADLKSEGFDVRV 119
           PGCPVC+ P   +    E+        +D I+ + GDM R+P   GS    + +G D R 
Sbjct: 66  PGCPVCVMPRARLDEAYELASM-----KDSIVLSLGDMMRVPGSYGSLIQAREKGLDARF 120

Query: 120 VYSIYDSYKIAQENRDKLVVHFSPGFETTTAPTAGMLETVINEGLDNFKIYSVHRLTPPA 179
           +YS   + +IA+EN  K V++ + GFETTT  TA +L     E L N   +  H L PP+
Sbjct: 121 LYSPMQALEIAKENPHKKVIYIAIGFETTTPMTASVLLNAKKEKLKNLFFHINHILVPPS 180

Query: 180 VEALLKAGTV-FHGLIDPGHVSTIIGVRGWAYLTEKYNIPQVVAGFEPVDVLLGILILIR 238
           V  +L+      + L+ P HVS I G + +A L +++ +P +V+GFEPVD+L  +L+L +
Sbjct: 181 VSTILEDKACRINALLAPSHVSVISGAQIYAPLVDRFKLPIIVSGFEPVDILESVLMLTK 240

Query: 239 MVKEGEAKIINEYSRVVKWEGNVKAQELINKFFEVKD-AKWRALGIIPQSGLELKREWKD 297
                EAK+  +Y R V +EGN KAQEL+N   EV++  +WR LG I +S L+LK  +  
Sbjct: 241 QALNKEAKLEIQYKRAVSYEGNTKAQELVNACMEVRENFEWRGLGNIKRSALKLKEAFAS 300

Query: 298 LEIRTLYNPDVP-KLPDLEKGCLCGAILRGLALPPQCPHFGKTCTPRHPIGPCMVSYEGT 356
            +   ++   +  K     K C CG IL+G+A P  C  F  TCTP++PIG CMVS EG 
Sbjct: 301 YDAEKVFKAYLSHKTSKENKACKCGEILKGIAKPLDCSLFATTCTPQNPIGSCMVSSEGA 360

Query: 357 CSIFYKY 363
           C+ +Y+Y
Sbjct: 361 CAAYYRY 367


>gb|AAA69239.1| (U29579) CG Site no. 33116; ORF_o373 [Escherichia coli]
           Length = 373
           
 Score =  243 bits (614), Expect = 2e-63
 Identities = 133/369 (36%), Positives = 200/369 (54%), Gaps = 13/369 (3%)

Query: 2   LEKFRDKEIAQKIVRKIHKEAKGFD-----ELRFMHVCGTHEDTVTRAGIRSLLPENVKI 56
           ++++R  E   +++  + + A          LR M VCG H   + + G+  LLPENV+ 
Sbjct: 4   VDEYRAPEQVMQLIEHLRERASHLSYTAERPLRIMEVCGGHTHAIFKFGLDQLLPENVEF 63

Query: 57  MSGPGCPVCITPVEDIVRMMEIMRKAKEEGEDIILTTFGDMYRIPTPMGSFADLKSEGFD 116
           + GPGCPVC+ P+  I   +EI         ++I  TFGD  R+P   GS    K+ G D
Sbjct: 64  IHGPGCPVCVLPMGRIDTCVEIASHP-----EVIFCTFGDAMRVPGKQGSLLQAKARGAD 118

Query: 117 VRVVYSIYDSYKIAQENRDKLVVHFSPGFETTTAPTAGMLETVINEGLDNFKIYSVHRLT 176
           VR+VYS  D+ K+AQEN  + VV F  GFETT   TA  L+      + NF  +  H   
Sbjct: 119 VRIVYSPMDALKLAQENPTRKVVFFGLGFETTMPTTAITLQQAKARDVQNFYFFCQHITL 178

Query: 177 PPAVEALL-KAGTVFHGLIDPGHVSTIIGVRGWAYLTEKYNIPQVVAGFEPVDVLLGILI 235
            P + +LL +        + PGHVS +IG   + ++   ++ P VVAGFEP+D+L G+++
Sbjct: 179 IPTLRSLLEQPDNGIDAFLAPGHVSMVIGTDAYNFIASDFHRPLVVAGFEPLDLLQGVVM 238

Query: 236 LIRMVKEGEAKIINEYSRVVKWEGNVKAQELINKFFEVK-DAKWRALGIIPQSGLELKRE 294
           L++      +K+ N+Y RVV   GN+ AQ+ I   F V  D++WR LG+I  SG+ L  +
Sbjct: 239 LVQQKIAAHSKVENQYRRVVPDAGNLLAQQAIXDVFCVNGDSEWRGLGVIESSGVHLTPD 298

Query: 295 WKDLEIRTLYNPDVPKLPDLEKGCLCGAILRGLALPPQCPHFGKTCTPRHPIGPCMVSYE 354
           ++  +    + P   ++ D +    CG +L G   P QCP FG TC P+   G  MVS E
Sbjct: 299 YQRFDAEAHFRPAPQQVCD-DPRARCGEVLTGKCKPHQCPLFGNTCNPQTAFGALMVSSE 357

Query: 355 GTCSIFYKY 363
           G C+ +Y+Y
Sbjct: 358 GACAAWYQY 366


>sp|P24192|HYPD_ECOLI HYDROGENASE ISOENZYMES FORMATION PROTEIN HYPD >gi|95944|pir||S15200
           hydrogenase expression/formation protein HypD -
           Escherichia coli >gi|41778|emb|CAA38415.1| (X54543)
           hydrogenase isoenzyme hypD [Escherichia coli]
           >gi|1789084|gb|AAC75771.1| (AE000356) pleiotrophic
           effects on 3 hydrogenase isozymes [Escherichia coli K12]
           Length = 373
           
 Score =  243 bits (613), Expect = 3e-63
 Identities = 133/369 (36%), Positives = 200/369 (54%), Gaps = 13/369 (3%)

Query: 2   LEKFRDKEIAQKIVRKIHKEAKGFD-----ELRFMHVCGTHEDTVTRAGIRSLLPENVKI 56
           ++++R  E   +++  + + A          LR M VCG H   + + G+  LLPENV+ 
Sbjct: 4   VDEYRAPEQVMQLIEHLRERASHLSYTAERPLRIMEVCGGHTHAIFKFGLDQLLPENVEF 63

Query: 57  MSGPGCPVCITPVEDIVRMMEIMRKAKEEGEDIILTTFGDMYRIPTPMGSFADLKSEGFD 116
           + GPGCPVC+ P+  I   +EI         ++I  TFGD  R+P   GS    K+ G D
Sbjct: 64  IHGPGCPVCVLPMGRIDTCVEIASHP-----EVIFCTFGDAMRVPGKQGSLLQAKARGAD 118

Query: 117 VRVVYSIYDSYKIAQENRDKLVVHFSPGFETTTAPTAGMLETVINEGLDNFKIYSVHRLT 176
           VR+VYS  D+ K+AQEN  + VV F  GFETT   TA  L+      + NF  +  H   
Sbjct: 119 VRIVYSPMDALKLAQENPTRKVVFFGLGFETTMPTTAITLQQAKARDVQNFYFFCQHITL 178

Query: 177 PPAVEALL-KAGTVFHGLIDPGHVSTIIGVRGWAYLTEKYNIPQVVAGFEPVDVLLGILI 235
            P + +LL +        + PGHVS +IG   + ++   ++ P VVAGFEP+D+L G+++
Sbjct: 179 IPTLRSLLEQPDNGIDAFLAPGHVSMVIGTDAYNFIASDFHRPLVVAGFEPLDLLQGVVM 238

Query: 236 LIRMVKEGEAKIINEYSRVVKWEGNVKAQELINKFFEVK-DAKWRALGIIPQSGLELKRE 294
           L++      +K+ N+Y RVV   GN+ AQ+ I   F V  D++WR LG+I  SG+ L  +
Sbjct: 239 LVQQKIAAHSKVENQYRRVVPDAGNLLAQQAIADVFCVNGDSEWRGLGVIESSGVHLTPD 298

Query: 295 WKDLEIRTLYNPDVPKLPDLEKGCLCGAILRGLALPPQCPHFGKTCTPRHPIGPCMVSYE 354
           ++  +    + P   ++ D +    CG +L G   P QCP FG TC P+   G  MVS E
Sbjct: 299 YQRFDAEAHFRPAPQQVCD-DPRARCGEVLTGKCKPHQCPLFGNTCNPQTAFGALMVSSE 357

Query: 355 GTCSIFYKY 363
           G C+ +Y+Y
Sbjct: 358 GACAAWYQY 366


>pir||S59984 hypD protein - Rhodobacter capsulatus >gi|46055|emb|CAA43328.1|
           (X61007) HypD [Rhodobacter capsulatus]
           Length = 473
           
 Score =  236 bits (597), Expect = 2e-61
 Identities = 129/371 (34%), Positives = 200/371 (53%), Gaps = 15/371 (4%)

Query: 4   KFRDKEIAQKIVRKIHKEAKGFDE-----LRFMHVCGTHEDTVTRAGIRSLLPENVKIMS 58
           +FRD  +A+ ++ +I + A          +  M +CG H  ++ R G+  L+   ++ + 
Sbjct: 102 EFRDPALAKGLLAEIARLADQIGATAEKPVHIMEICGGHTHSIFRYGLDKLIHPGIEFIH 161

Query: 59  GPGCPVCITPVEDIVRMMEIMRKAKEEGEDIILTTFGDMYRIPTPMGSFADLKSEGFDVR 118
           GPGCPVC+ P   +   +EI  +      ++I  TFGD  R+P    S    K+ G D+R
Sbjct: 162 GPGCPVCVLPRARVDECIEIAGRP-----EVIFCTFGDAMRVPGSKLSLMQAKAAGADIR 216

Query: 119 VVYSIYDSYKIAQENRDKLVVHFSPGFETTTAPTAGMLETVINEGLDNFKIYSVHRLTPP 178
           +VYS  D+ ++A+ N  + VV F  GFETTT  TA  ++    EGL NF ++  H   P 
Sbjct: 217 MVYSPLDALELARRNPGREVVFFGLGFETTTPSTALAIQQAAREGLANFSVFCNHITVPE 276

Query: 179 AVEALLKAGTV-FHGLIDPGHVSTIIGVRGWAYLTEKYNIPQVVAGFEPVDVLLGILILI 237
            + ALL    +   G I PGHVS +IG+  + ++ E Y  P VVAGFEP D+L  +L+++
Sbjct: 277 PIRALLDDPYMRLDGFIGPGHVSMVIGIHPYDFIAEDYGKPLVVAGFEPTDLLQSVLMVL 336

Query: 238 RMVKEGEAKIINEYSRVVKWEGNVKAQELINKFFEVKDA-KWRALGIIPQSGLELKREWK 296
           R + +G A I N+Y+RVV   GN  +   I   +E + + +WR LG I  SGL ++  ++
Sbjct: 337 RQISQGRAAIENQYARVVPEHGNRVSLAAIADVYERRPSFEWRGLGEIDASGLRIRAAYR 396

Query: 297 DLEIRTLYNPDVP---KLPDLEKGCLCGAILRGLALPPQCPHFGKTCTPRHPIGPCMVSY 353
             +    +           +  +GC CGA++ G   P  C  FGK CTP  P+G  MVS 
Sbjct: 397 AHDAEEKFGVGYAGQRAAVEEAEGCACGAVMTGRMKPVACAQFGKGCTPEMPLGALMVSS 456

Query: 354 EGTCSIFYKYG 364
           EG C+ +++YG
Sbjct: 457 EGACAAYWQYG 467


>sp|P26411|HYPD_RHOCA HYDROGENASE EXPRESSION/FORMATION PROTEIN HYPD
           >gi|2126467|pir||S59985 hypD protein - Rhodobacter
           capsulatus
           Length = 377
           
 Score =  236 bits (597), Expect = 2e-61
 Identities = 129/371 (34%), Positives = 200/371 (53%), Gaps = 15/371 (4%)

Query: 4   KFRDKEIAQKIVRKIHKEAKGFDE-----LRFMHVCGTHEDTVTRAGIRSLLPENVKIMS 58
           +FRD  +A+ ++ +I + A          +  M +CG H  ++ R G+  L+   ++ + 
Sbjct: 6   EFRDPALAKGLLAEIARLADQIGATAEKPVHIMEICGGHTHSIFRYGLDKLIHPGIEFIH 65

Query: 59  GPGCPVCITPVEDIVRMMEIMRKAKEEGEDIILTTFGDMYRIPTPMGSFADLKSEGFDVR 118
           GPGCPVC+ P   +   +EI  +      ++I  TFGD  R+P    S    K+ G D+R
Sbjct: 66  GPGCPVCVLPRARVDECIEIAGRP-----EVIFCTFGDAMRVPGSKLSLMQAKAAGADIR 120

Query: 119 VVYSIYDSYKIAQENRDKLVVHFSPGFETTTAPTAGMLETVINEGLDNFKIYSVHRLTPP 178
           +VYS  D+ ++A+ N  + VV F  GFETTT  TA  ++    EGL NF ++  H   P 
Sbjct: 121 MVYSPLDALELARRNPGREVVFFGLGFETTTPSTALAIQQAAREGLANFSVFCNHITVPE 180

Query: 179 AVEALLKAGTV-FHGLIDPGHVSTIIGVRGWAYLTEKYNIPQVVAGFEPVDVLLGILILI 237
            + ALL    +   G I PGHVS +IG+  + ++ E Y  P VVAGFEP D+L  +L+++
Sbjct: 181 PIRALLDDPYMRLDGFIGPGHVSMVIGIHPYDFIAEDYGKPLVVAGFEPTDLLQSVLMVL 240

Query: 238 RMVKEGEAKIINEYSRVVKWEGNVKAQELINKFFEVKDA-KWRALGIIPQSGLELKREWK 296
           R + +G A I N+Y+RVV   GN  +   I   +E + + +WR LG I  SGL ++  ++
Sbjct: 241 RQISQGRAAIENQYARVVPEHGNRVSLAAIADVYERRPSFEWRGLGEIDASGLRIRAAYR 300

Query: 297 DLEIRTLYNPDVP---KLPDLEKGCLCGAILRGLALPPQCPHFGKTCTPRHPIGPCMVSY 353
             +    +           +  +GC CGA++ G   P  C  FGK CTP  P+G  MVS 
Sbjct: 301 AHDAEEKFGVGYAGQRAAVEEAEGCACGAVMTGRMKPVACAQFGKGCTPEMPLGALMVSS 360

Query: 354 EGTCSIFYKYG 364
           EG C+ +++YG
Sbjct: 361 EGACAAYWQYG 371


>gb|AAB64435.1| (AF006594) HupD [Anabaena PCC7120]
           Length = 199
           
 Score =  146 bits (365), Expect = 4e-34
 Identities = 71/174 (40%), Positives = 106/174 (60%), Gaps = 2/174 (1%)

Query: 192 GLIDPGHVSTIIGVRGWAYLTEKYNIPQVVAGFEPVDVLLGILILIRMVKEGEAKIINEY 251
           G I PGHVS +IG   + ++ ++Y+ P VV+GFEP+D+   I +L++ + E   ++ N+Y
Sbjct: 7   GFIGPGHVSMVIGTEPYEFIAQQYHKPIVVSGFEPLDIFQSIWMLLQQLVENRCEVENQY 66

Query: 252 SRVVKWEGNVKAQELINKFFEVKDA-KWRALGIIPQSGLELKREWKDLEIRTLYNPDVPK 310
           +R+V+  GN  A   ++K F V++   WR L  IP SGL+++ E+   +    +     K
Sbjct: 67  NRLVQKGGNQIALAAMHKVFAVREKFAWRGLDEIPDSGLKIREEYAQFDAELKFTIPNLK 126

Query: 311 LPDLEKGCLCGAILRGLALPPQCPHFGKTCTPRHPIGPCMVSYEGTCSIFYKYG 364
           + D  K C CG IL+G+  P QC  FG  CTP  PIG CMVS EG C+ +YKYG
Sbjct: 127 VAD-HKACKCGEILKGVPQPWQCKVFGTACTPETPIGTCMVSSEGACAAYYKYG 179


>gb|AAF20001.1|AF214145_8 (AF214145) hydrogenase maturating protein HypD [Rhodobacter
           sphaeroides]
           Length = 123
           
 Score = 69.5 bits (167), Expect = 6e-11
 Identities = 38/123 (30%), Positives = 60/123 (47%), Gaps = 10/123 (8%)

Query: 4   KFRDKEIAQKIVRKIHKEAKGFDELR-----FMHVCGTHEDTVTRAGIRSLLPENVKIMS 58
           +FRD  +A+ ++  I   A      R      M +CG H   + R G+  L+ E ++ + 
Sbjct: 6   EFRDPALARSLLAAIAARADEMGATRARPLHIMEICGGHTHAIFRYGLDRLVHEGIEFIH 65

Query: 59  GPGCPVCITPVEDIVRMMEIMRKAKEEGEDIILTTFGDMYRIPTPMGSFADLKSEGFDVR 118
           GPGCPVC+ P+  + + + I          +ILTTF     +P   GS    K+ G D+R
Sbjct: 66  GPGCPVCVLPIPPLHQSIPI-----PHPPHLILTTFPHPIPLPGARGSLLQAKARGADIR 120

Query: 119 VVY 121
           +VY
Sbjct: 121 MVY 123


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.322    0.142    0.433 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 146479878
Number of Sequences: 2977
Number of extensions: 6442854
Number of successful extensions: 12846
Number of sequences better than 1.0e-10: 21
Number of HSP's better than  0.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 12754
Number of HSP's gapped (non-prelim): 21
length of query: 367
length of database: 189,106,746
effective HSP length: 52
effective length of query: 315
effective length of database: 157,985,422
effective search space: 49765407930
effective search space used: 49765407930
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.9 bits)
S2: 166 (69.1 bits)