BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1560 (hypF) DE:hydrogenase expression/formation regulatory
protein (hypF)
         (773 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||D75031 hydrogenase expression/formation regulatory protein ...  1571  0.0
pir||A71079 probable transcription regulatory protein hypF - Pyr...  1469  0.0
sp|Q58123|Y713_METJA PUTATIVE HYDROGENASE EXPRESSION/FORMATION P...   680  0.0
pir||C69038 transcription regulator HypF homolog - Methanobacter...   624  e-177
gi|11498962 hydrogenase expression/formation regulatory protein ...   573  e-162
pir||T45111 hypF protein [imported] - Methanosarcina mazei (frag...   566  e-160
pir||B70359 transcription regulator HypF - Aquifex aeolicus >gi|...   558  e-158
sp|O07451|HYF2_ALCEU HYDROGENASE MATURATION PROTEIN HYPF2 >gi|21...   467  e-130
sp|P40596|HYPF_AZOVI HYDROGENASE MATURATION PROTEIN HYPF              457  e-127
sp|Q43950|HYPF_AZOCH HYDROGENASE MATURATION PROTEIN HYPF              447  e-124
pir||S23441 hypothetical protein 6 - Azotobacter vinelandii >gi|...   446  e-124
sp|P28156|HYPF_RHILV HYDROGENASE MATURATION PROTEIN HYPF >gi|420...   440  e-122
sp|Q55638|HYPF_SYNY3 HYDROGENASE MATURATION PROTEIN HYPF >gi|744...   437  e-121
pir||JN0648 hydrogenase expression/formation protein HupY - Azot...   436  e-121
pir||E81410 transcription regulatory protein hypF Cj0622 [import...   433  e-120
sp|P30131|HYPF_ECOLI HYDROGENASE MATURATION PROTEIN HYPF >gi|744...   428  e-119
gb|AAA69222.1| (U29579) CG Site No. 18232; alternate gene name h...   428  e-118
sp|Q02987|HYPF_RHOCA HYDROGENASE MATURATION PROTEIN HYPF >gi|479...   418  e-116
dbj|BAA03315.1| (D14422) HYDA [Escherichia coli]                      410  e-113
emb|CAB39912.1| (Y14197) uptake hydrogenase [Rhodobacter sphaero...   401  e-110
pir||H64525 transcription regulator - Helicobacter pylori (strai...   371  e-101
pir||G71981 probable transcription regulator - Helicobacter pylo...   360  4e-98
emb|CAA85443.1| (Z36981) HYPF [Rhizobium leguminosarum]               343  5e-93
sp|P45805|HYF1_ALCEU HYDROGENASE MATURATION PROTEIN HYPF1 >gi|21...   163  6e-39

>pir||D75031 hydrogenase expression/formation regulatory protein (hypf) PAB1560
           - Pyrococcus abyssi (strain Orsay)
           >gi|5458658|emb|CAB50145.1| (AJ248287) hydrogenase
           expression/formation regulatory protein (hypF)
           [Pyrococcus abyssi]
           Length = 773
           
 Score = 1571 bits (4023), Expect = 0.0
 Identities = 773/773 (100%), Positives = 773/773 (100%)

Query: 1   MKAYRIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDL 60
           MKAYRIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDL
Sbjct: 1   MKAYRIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDL 60

Query: 61  YRKKPPIAKIEKVEREEIPIQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDP 120
           YRKKPPIAKIEKVEREEIPIQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDP
Sbjct: 61  YRKKPPIAKIEKVEREEIPIQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDP 120

Query: 121 TNKRYMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPV 180
           TNKRYMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPV
Sbjct: 121 TNKRYMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPV 180

Query: 181 ACPVCGPSYRLYTSDGKEITGDPLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVVAEL 240
           ACPVCGPSYRLYTSDGKEITGDPLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVVAEL
Sbjct: 181 ACPVCGPSYRLYTSDGKEITGDPLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVVAEL 240

Query: 241 RKRLFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKREPFPLPENLAPG 300
           RKRLFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKREPFPLPENLAPG
Sbjct: 241 RKRLFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKREPFPLPENLAPG 300

Query: 301 LHTIGVMLPYAGTHYILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEKLKDVADYLLLHN 360
           LHTIGVMLPYAGTHYILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEKLKDVADYLLLHN
Sbjct: 301 LHTIGVMLPYAGTHYILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEKLKDVADYLLLHN 360

Query: 361 RRIPNRADDSVVRFVDGRRAVIRRSRGFVPLWIEIPFEYKGLAVGAELMNAFGVAKNGKV 420
           RRIPNRADDSVVRFVDGRRAVIRRSRGFVPLWIEIPFEYKGLAVGAELMNAFGVAKNGKV
Sbjct: 361 RRIPNRADDSVVRFVDGRRAVIRRSRGFVPLWIEIPFEYKGLAVGAELMNAFGVAKNGKV 420

Query: 421 YPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPNYNTTKLAMEIAEEFNA 480
           YPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPNYNTTKLAMEIAEEFNA
Sbjct: 421 YPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPNYNTTKLAMEIAEEFNA 480

Query: 481 EFLQVQHHYAHVASVMAEHNLEEVVGIALDGVGYGTDGKTWGGEIIYLSYEDIERLAHLE 540
           EFLQVQHHYAHVASVMAEHNLEEVVGIALDGVGYGTDGKTWGGEIIYLSYEDIERLAHLE
Sbjct: 481 EFLQVQHHYAHVASVMAEHNLEEVVGIALDGVGYGTDGKTWGGEIIYLSYEDIERLAHLE 540

Query: 541 YYPLPGGDLASYYPLRALIGILSLNHEIEEVENTIRKFCPNAIKSLKYGETELKVILRQL 600
           YYPLPGGDLASYYPLRALIGILSLNHEIEEVENTIRKFCPNAIKSLKYGETELKVILRQL
Sbjct: 541 YYPLPGGDLASYYPLRALIGILSLNHEIEEVENTIRKFCPNAIKSLKYGETELKVILRQL 600

Query: 601 SSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLESFASQGKNDLKLTIPVEGEE 660
           SSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLESFASQGKNDLKLTIPVEGEE
Sbjct: 601 SSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLESFASQGKNDLKLTIPVEGEE 660

Query: 661 IRVSELFEEVLDLMGKASPRDIAYSIHLALARVFAEVSVEKAKEFGAKTVVLGGGVGYNE 720
           IRVSELFEEVLDLMGKASPRDIAYSIHLALARVFAEVSVEKAKEFGAKTVVLGGGVGYNE
Sbjct: 661 IRVSELFEEVLDLMGKASPRDIAYSIHLALARVFAEVSVEKAKEFGAKTVVLGGGVGYNE 720

Query: 721 LIVKTVRKIVEGNGLKFLTTYEVPRGDNGINVGQAFLGGLYLEGYLNREDLSI 773
           LIVKTVRKIVEGNGLKFLTTYEVPRGDNGINVGQAFLGGLYLEGYLNREDLSI
Sbjct: 721 LIVKTVRKIVEGNGLKFLTTYEVPRGDNGINVGQAFLGGLYLEGYLNREDLSI 773


>pir||A71079 probable transcription regulatory protein hypF - Pyrococcus
           horikoshii >gi|3257308|dbj|BAA29991.1| (AP000004) 773aa
           long hypothetical transcriptional regulatory protein
           hypF [Pyrococcus horikoshii]
           Length = 773
           
 Score = 1469 bits (3762), Expect = 0.0
 Identities = 706/773 (91%), Positives = 748/773 (96%)

Query: 1   MKAYRIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDL 60
           MKAYRIHVQGIVQAVGFRPFVYRIAHAHNL+G+VRNLGDAGVEIV+EG EEDIEGFL DL
Sbjct: 1   MKAYRIHVQGIVQAVGFRPFVYRIAHAHNLKGFVRNLGDAGVEIVIEGNEEDIEGFLVDL 60

Query: 61  YRKKPPIAKIEKVEREEIPIQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDP 120
           Y+KKPPIA+I+KVE+EEIP QGFDRFYIEKSSTEKKGEGDSIIPPDIAIC+DCL+ELFDP
Sbjct: 61  YKKKPPIARIDKVEKEEIPPQGFDRFYIEKSSTEKKGEGDSIIPPDIAICDDCLKELFDP 120

Query: 121 TNKRYMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPV 180
           TNKRYMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMC+FC+SEYEDPLNRRYHAEPV
Sbjct: 121 TNKRYMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCEFCRSEYEDPLNRRYHAEPV 180

Query: 181 ACPVCGPSYRLYTSDGKEITGDPLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVVAEL 240
           ACP CGPSYRLYT+DG EI GDPLRKAAKLIDKGYI+AIKGIGGIHLACDATREDVV EL
Sbjct: 181 ACPTCGPSYRLYTNDGNEIVGDPLRKAAKLIDKGYIVAIKGIGGIHLACDATREDVVVEL 240

Query: 241 RKRLFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKREPFPLPENLAPG 300
           RKR+FRPQKPFAIMAKDLET++ FAY+S EEEEELTSYRRPIVAL+K+EPFPLPENLAPG
Sbjct: 241 RKRIFRPQKPFAIMAKDLETIRTFAYVSPEEEEELTSYRRPIVALKKKEPFPLPENLAPG 300

Query: 301 LHTIGVMLPYAGTHYILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEKLKDVADYLLLHN 360
           LHTIGVMLPYAGTHYILFHWS+TPVYVMTSANFPGMPMIKDNEEAFEKL+DVADYLLLHN
Sbjct: 301 LHTIGVMLPYAGTHYILFHWSETPVYVMTSANFPGMPMIKDNEEAFEKLRDVADYLLLHN 360

Query: 361 RRIPNRADDSVVRFVDGRRAVIRRSRGFVPLWIEIPFEYKGLAVGAELMNAFGVAKNGKV 420
           RRIPNRADDSVVRFVDGRRAVIRRSRGFVPL IEIPFEYKGLAVGA LMNAFGV+K+GKV
Sbjct: 361 RRIPNRADDSVVRFVDGRRAVIRRSRGFVPLGIEIPFEYKGLAVGAGLMNAFGVSKSGKV 420

Query: 421 YPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPNYNTTKLAMEIAEEFNA 480
           YPSQYIG+TSKIEVLEFMR+AI+HFFKILRI++LDLVVADLHP+YNTTKL MEIAEEF A
Sbjct: 421 YPSQYIGDTSKIEVLEFMRDAIRHFFKILRIDSLDLVVADLHPSYNTTKLGMEIAEEFGA 480

Query: 481 EFLQVQHHYAHVASVMAEHNLEEVVGIALDGVGYGTDGKTWGGEIIYLSYEDIERLAHLE 540
           EFLQVQHHYAHVASVMAEHNLEEVVGIALDGVGYGTDGKTWGGE+IYL YED+ERLAH+E
Sbjct: 481 EFLQVQHHYAHVASVMAEHNLEEVVGIALDGVGYGTDGKTWGGEVIYLGYEDVERLAHIE 540

Query: 541 YYPLPGGDLASYYPLRALIGILSLNHEIEEVENTIRKFCPNAIKSLKYGETELKVILRQL 600
           YYPLPGGDLASYYPLRALIGILSLNH+ EEVE  IR+FCPNAIKSLKYGETE KVILRQL
Sbjct: 541 YYPLPGGDLASYYPLRALIGILSLNHDFEEVEKIIREFCPNAIKSLKYGETEFKVILRQL 600

Query: 601 SSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLESFASQGKNDLKLTIPVEGEE 660
           SSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLESFA QGKNDL LT+P+EGEE
Sbjct: 601 SSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLESFAYQGKNDLNLTVPIEGEE 660

Query: 661 IRVSELFEEVLDLMGKASPRDIAYSIHLALARVFAEVSVEKAKEFGAKTVVLGGGVGYNE 720
           I+VSELFEEVL+LMGK +PRDIAYS+HLALAR FAEVSVEKAKEFG KTVVLGGGVGYNE
Sbjct: 661 IKVSELFEEVLELMGKVNPRDIAYSVHLALARAFAEVSVEKAKEFGVKTVVLGGGVGYNE 720

Query: 721 LIVKTVRKIVEGNGLKFLTTYEVPRGDNGINVGQAFLGGLYLEGYLNREDLSI 773
           LIVKT+RKIVEG  L+FLTTYEVPRGDNGINVGQAFLGGLYLEGYLNREDLSI
Sbjct: 721 LIVKTIRKIVEGRELRFLTTYEVPRGDNGINVGQAFLGGLYLEGYLNREDLSI 773


>sp|Q58123|Y713_METJA PUTATIVE HYDROGENASE EXPRESSION/FORMATION PROTEIN MJ0713
           >gi|2127975|pir||A64389 hydrogenase accessory protein -
           Methanococcus jannaschii >gi|1591430|gb|AAB98708.1|
           (U67518) hydrogenase expression regulatory protein
           (hypF) [Methanococcus jannaschii]
           Length = 766
           
 Score =  680 bits (1735), Expect = 0.0
 Identities = 351/759 (46%), Positives = 499/759 (65%), Gaps = 24/759 (3%)

Query: 5   RIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDLYRKK 64
           RI V+GIVQ VGFRPFVYRIA  +NL+GYV+N+G+  VEI++EG++EDI  F+ DL  KK
Sbjct: 13  RIKVKGIVQGVGFRPFVYRIAKKNNLKGYVKNMGNY-VEILIEGKKEDIRNFINDLKNKK 71

Query: 65  PPIAKIEKVEREEIP-IQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDPTNK 123
           PP+++I+K++ EEI  I+ FD FYI KS   K  E +  IP D+AIC+DCL+E+ D  ++
Sbjct: 72  PPLSRIDKLDIEEIKGIEEFDDFYIIKSENAKDEE-EGTIPADVAICDDCLKEMLDKNDR 130

Query: 124 RYMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPVACP 183
           RY YPFI CTNCGPRFTI+E LPYDRENT+MR+FP+C+ C  EY++PL+RR+HA+   CP
Sbjct: 131 RYRYPFIACTNCGPRFTIVEKLPYDRENTSMRDFPLCEKCLEEYKNPLDRRFHAQATCCP 190

Query: 184 VCGPSYRLYTSDGKEITG---DPLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVVAEL 240
           +CGP  +++ SDGKEI     + +R+  KL+++G+I+AIKGIGG HLAC    +DVV EL
Sbjct: 191 ICGP--KVFLSDGKEIIAEKDEAIRETVKLLEEGHILAIKGIGGTHLACKVGEDDVVLEL 248

Query: 241 RKRLFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKREPF-PLPENLAP 299
           RKRL RP +PFA+M+K +E  + FA    +E+  L S RRPIV L+K + +         
Sbjct: 249 RKRLGRPTQPFAVMSK-IEYTELFAEFDEDEKNALLSLRRPIVVLKKSQDYDKYFSKYVS 307

Query: 300 GLHTIGVMLPYAGTHYILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEKLKDVADYLLLH 359
            L TIGVM PY+G HY+LF   K   YVMTSAN PG+PM+KDN+E  +KL  +ADY LLH
Sbjct: 308 NLDTIGVMFPYSGLHYLLF--DKEIAYVMTSANLPGLPMVKDNDEILKKLNGIADYFLLH 365

Query: 360 NRRIPNRADDSVVRFVDGRRAVIRRSRGFV--PLWIEIPFEYKGLAVGAELMNAFGVAKN 417
           NRRI NR DDSVV+ V  R   +RRSRGF   P+ + I      L VGAEL +   + K 
Sbjct: 366 NRRIVNRCDDSVVKKVADRLVFLRRSRGFAPEPVKVNINNNKNILCVGAELNSTACIVKR 425

Query: 418 GKVYPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPNYNTTKLAMEIAEE 477
            K Y +QYIGNTSK E   ++R+AI +  ++   N +D +V DLHP +N+TKLA E++E+
Sbjct: 426 DKFYLTQYIGNTSKYETFCYLRDAINNILRLTNTNKIDAIVCDLHPQFNSTKLAEELSEK 485

Query: 478 FNAEFLQVQHHYAHVASVMAEHN-LEEVVGIALDGVGYGTDGKTWGGEIIYLSYEDIERL 536
           F AE  +VQHH+AH  S++ ++N  ++ + ++LDGVGYG DG  WGGE++      +ER+
Sbjct: 486 FGAEIFRVQHHFAHAYSLLGDNNYFDDAIILSLDGVGYGLDGNIWGGEVLLFKDGKMERV 545

Query: 537 AHLEYYPLPGGDLASYYPLRALIGILSLNHEIEEVENTIRKFCPNAIKSLKYGETELKVI 596
            HLE     GGDLA+ YPLR L+ IL      EE  + I+++         + E EL+++
Sbjct: 546 GHLEEQYQLGGDLATKYPLRMLLSIL-YKAIGEEAFDFIKRY-------NFFSEKELRLL 597

Query: 597 LRQLSSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLESFASQGKNDLKLTIPV 656
             QL   +N    +STGRVLDA S LL + + + Y+GEP+++LE  A++ K D+ +   +
Sbjct: 598 KFQLEKKLNCPITTSTGRVLDAVSALLGICFEKTYDGEPSIRLEPVANRFKGDINIEPKI 657

Query: 657 EGEEIRVSELFEEVLD-LMGKASPRDIAYSIHLALARVFAEVSVEKAKEFGAKTVVLGGG 715
           +   +  +EL  +  + L+   +   IA+  H+ +A    E++ + + +FG  T+ + GG
Sbjct: 658 KNNILNTTELIYKSYEMLLNNENKEKIAHFAHIYIADGLFEIAKKISNKFGINTIGITGG 717

Query: 716 VGYNELIVKTVRKIVEGNGLKFLTTYEVPRGDNGINVGQ 754
           V YN++I + +    +  G  F+    VP GD GI+ GQ
Sbjct: 718 VSYNKIITERIMNNAKREGFNFIYHQRVPNGDGGISFGQ 756


>pir||C69038 transcription regulator HypF homolog - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622395|gb|AAB85769.1| (AE000894) transcriptional
           regulator HypF homolog [Methanobacterium
           thermoautotrophicum]
           Length = 729
           
 Score =  624 bits (1592), Expect = e-177
 Identities = 332/726 (45%), Positives = 455/726 (61%), Gaps = 21/726 (2%)

Query: 42  VEIVVEGREEDIEGFLRDLYRKKPPIAKIEKVERE--EIPIQGFDRFYIEKSSTEKKGEG 99
           VEIV+EG  E IE F+  L + KPPI++I  ++++  E+    F  F I++SS+   G  
Sbjct: 5   VEIVLEGSHEGIEEFIERLKKDKPPISRINSIKKDIFEVNEASFTEFIIKESSSSSSGT- 63

Query: 100 DSIIPPDIAICEDCLRELFDPTNKRYMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPM 159
            S+IP D+A C  CL E+ D  N+RY+YPF  CT+CGPRFT+IE +PYDRE T+MR+FP+
Sbjct: 64  -SVIPADVATCSSCLEEMMDENNRRYLYPFTACTDCGPRFTVIESIPYDRERTSMRDFPL 122

Query: 160 CDFCKSEYEDPLNRRYHAEPVACPVCGPSYRLYTSDGKEITGDPLRKAAKLIDKGYIIAI 219
           C  C  EY +PL+RRYHAE   CP+CGP   LY  DG   T DP++ AA+L+D G I+A+
Sbjct: 123 CSSCMEEYLNPLDRRYHAEATCCPICGPKPFLYR-DGILKTHDPIKMAAELLDDGSILAV 181

Query: 220 KGIGGIHLACDATREDVVAELRKRLFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYR 279
           KGIGG HL C A  ++VV  LR  L RP +PFA M+ DLE+++ +A IS  EEE LTS R
Sbjct: 182 KGIGGTHLVCRADDDEVVKRLRSGLGRPNQPFACMSPDLESIESYASISDVEEEALTSRR 241

Query: 280 RPIVALRKREPFPLPENLAPGLHTIGVMLPYAGTHYILFHWSKTPVYVMTSANFPGMPMI 339
           RPIV L+K   + L  ++APGLH IGVMLPY+G H++L  +++ P YVMTSAN PG PM 
Sbjct: 242 RPIVVLKKSRDYCLAPSVAPGLHNIGVMLPYSGLHHVLLRYTEAPAYVMTSANRPGDPMF 301

Query: 340 KDNEEAFEKLKDVADYLLLHNRRIPNRADDSVVRFVDGRRAVIRRSRGFVPLWIEIPF-- 397
            +N E    L+ +ADY LLH+RRI NR DDSVVRF  G  A IRRSRG+ P   EIP   
Sbjct: 302 IENTEIIGGLQGIADYFLLHDRRIVNRCDDSVVRFRGGEMAFIRRSRGYAPEPYEIPHVA 361

Query: 398 -EYKGLAVGAELMNAFGVAKNGKVYPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDL 456
            +   + +G EL   F V K G+ Y SQ+IGNTS+ + L F+++A+ +   I     +D+
Sbjct: 362 GDVSAICLGPELDVTFSVLKGGQCYVSQHIGNTSRYDTLLFLKDAVDYLMGITGTEDVDV 421

Query: 457 VVADLHPNYNTTKLAMEIAEEFNAEFLQVQHHYAHVASVMAEHNLEEVVGIALDGVGYGT 516
           +  DLHP + TT  A E+A  F+AE L+VQHH+AH  ++M +  ++E + IA DGVGYG 
Sbjct: 422 IACDLHPQFLTTSYAEELASRFSAEVLRVQHHHAHALALMLDAGVDECICIAADGVGYGD 481

Query: 517 DGKTWGGEIIYLSYEDIERLAHLEYYPLPGGDLASYYPLRALIGILSLNHEIEEVENTIR 576
           DG +WGGEI++    D ERL  L    +PGGDLA+ YP R L+ +L   +E +  E    
Sbjct: 482 DGTSWGGEILHCHGSDYERLGSLMPQRMPGGDLATRYPARMLLSMLRGRYEGDLQE---- 537

Query: 577 KFCPNAIKSLKYGETELKVILRQLSSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPA 636
            F         +GE E+ V++RQL SG+N   ++ TGRVLDA S  L +   R YEGE A
Sbjct: 538 LFSERYSDYFPHGEREIGVVMRQLESGLNTGISTGTGRVLDAISAALRICGVRTYEGECA 597

Query: 637 MKLESFASQGKNDLKLTIPVEGEE------IRVSELFEEVLDLMGKASPR-DIAYSIHLA 689
           MKLES A +     KL++P E +E      +  S +  +V++L+ +   R +IA++   A
Sbjct: 598 MKLESEAFRASG--KLSMPFEVKEKGGRYILDTSAILLDVMELIDRGEDRAEIAHAAQKA 655

Query: 690 LARVFAEVSVEKAKEFGAKTVVLGGGVGYNELIVKTVRKIVEGNGLKFLTTYEVPRGDNG 749
           +A   AE++V  A + G K +   GGV YNE I   VR  V   G +F+       GD  
Sbjct: 656 VAEGLAEMAVLAADDAGVKCIGGTGGVFYNEAISLAVRDYVTERGYRFIQHRNSCAGDGS 715

Query: 750 INVGQA 755
           +++GQA
Sbjct: 716 VSLGQA 721


>gi|11498962 hydrogenase expression/formation regulatory protein (hypF)
           [Archaeoglobus fulgidus] >gi|7449698|pir||E69420
           hydrogenase expression/formation regulatory protein
           (hypF) homolog - Archaeoglobus fulgidus
           >gi|2649204|gb|AAB89876.1| (AE001009) hydrogenase
           expression/formation regulatory protein (hypF)
           [Archaeoglobus fulgidus]
           Length = 740
           
 Score =  573 bits (1461), Expect = e-162
 Identities = 332/778 (42%), Positives = 458/778 (58%), Gaps = 71/778 (9%)

Query: 4   YRIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDLYRK 63
           ++I V+G+VQ VGFRPFV+RIA    LRGYVRN GD  VEIVV+   E+   FL  L ++
Sbjct: 2   FKITVRGVVQGVGFRPFVHRIASRMGLRGYVRNTGDGSVEIVVDRNPEE---FLNILLKE 58

Query: 64  KPPIAKIEKVEREEIPIQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDPTNK 123
           +PP+  IE     +   +  + F I +S  +      S+ PPD+A+C+ CL E+ D  N+
Sbjct: 59  RPPLVVIEDFSVAKTNGEIPETFRIVESGGKSLL---SLPPPDVAVCDKCLEEVLDSKNR 115

Query: 124 RYMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPVACP 183
           RY+YPF  CT+CGPRFTI + LP+DRENT++ +FP+C  C+ EY D  +RRY A+ +ACP
Sbjct: 116 RYLYPFTSCTDCGPRFTISKSLPFDRENTSLADFPLCPDCRKEYGDIKDRRYFAQTIACP 175

Query: 184 VCGPSYRLYTSDGKEITGDPLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVVAELRKR 243
            CGP YR     G+   GD    AA  +D G IIAIKGIGG H+AC  T +DVV  LRK 
Sbjct: 176 RCGPQYRFVWKGGEGGIGD----AANALDSGKIIAIKGIGGYHIAC-LTEDDVVLRLRKL 230

Query: 244 LFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKREPFPLPENLAPGLHT 303
           L RPQ+PFA+M +DL + +  A +S EE  EL S  RPIV +RK+ PF   E +AP L T
Sbjct: 231 LNRPQQPFAVMVRDLSSAERVAELSNEERAELLSPARPIVVVRKKLPF---EAVAPELDT 287

Query: 304 IGVMLPYAGTHYILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEKLKDVADYLLLHNRRI 363
           IG+MLPY   H++LF   K    VMTSAN PG PM  D E   EK++   D  L+HN  I
Sbjct: 288 IGIMLPYTPLHHLLFQELKADYLVMTSANLPGEPMYID-ESIMEKME--LDGFLVHNLEI 344

Query: 364 PNRADDSVVRFVDGRRAVIRRSRGFVPLWIEIPFEYKGLAVGAELMNAFGVAKNGKVYPS 423
            NR DDSVV++V GRR +IRRSRGFVP  I+I   +  +AVGAEL N+  + K GK   S
Sbjct: 345 ANRVDDSVVKYVGGRRLLIRRSRGFVPQPIKIDIGFNAIAVGAELYNSIALLKEGKAVVS 404

Query: 424 QYIGNTSKIEVL-EFMREAIKHFFKILRINALDLVVADLHPNYNTTKLAMEIAEEFNAEF 482
           QYIGNT+      EF + A+K F + + +  +D +++D+HP +NTT  A ++++E +   
Sbjct: 405 QYIGNTANFRTYNEFFKRAVKFFARYMNLEKIDYIISDMHPLFNTTNFAEKLSKELSCRH 464

Query: 483 LQVQHHYAHVASVMAEHNLEEVVGIALDGVGYGTDGKTWGGEIIYLSYED--IERLAHLE 540
           ++VQHH+AH  SVMAE  LE  V I +DGVGYG DGK WGGE++ +  E    ER   LE
Sbjct: 465 IKVQHHFAHALSVMAEKGLERAVAITVDGVGYGMDGKVWGGEVLLIDLEKGRFERRGRLE 524

Query: 541 YYPLPGGDLASYYPLRALIGILSLNHEIEEVENTIRKFCPNAIKSLKYGETELKVILRQL 600
            + L GGD A+Y PLR  + +L   HE+      +  +C       KY + E   +++ L
Sbjct: 525 TFGLIGGDAATYRPLRIAVSLLK-RHEL------LEHYC-------KYEDVER--LIKAL 568

Query: 601 SSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLESFASQGKNDLKLTI------ 654
              +     +S GR LDA S +L V   R YEGEPAMKLE+ A   + ++K  I      
Sbjct: 569 PLAVK---TTSVGRFLDAVSAMLEVCLERTYEGEPAMKLEAAAEPHEVEVKPEIERRRET 625

Query: 655 -----PVEGE----EIRV-------SELFEEVLDLMGKASPRDIAYSIHLALARVFAEVS 698
                P + E    EI+V       +   E  L+  G+     IAY     +AR   E++
Sbjct: 626 CVYNSPFDTEGRQGEIKVLMLRDFFTRCMERYLEGEGRGK---IAYEAIAYVARGLGEIA 682

Query: 699 VEKAKEFGAKTVVLGGGVGYNELIVKTVRKIVEGNGLKFLTTYEVPRGDNGINVGQAF 756
           ++ A+      +++ GGVGYN   ++ V ++      + +     P GDNGI++GQ +
Sbjct: 683 LDAARNC---KILISGGVGYNRYFLREVERVCG----EIVVPSLYPLGDNGISLGQIY 733


>pir||T45111 hypF protein [imported] - Methanosarcina mazei (fragment)
           >gi|2982748|gb|AAC06379.1| (U47274) similar to
           transcriptional regulatory protein HypF in Rhizobium
           leguminosarum bv. viciae, Swiss-Prot Accession Number
           P28156 [Methanosarcina mazei]
           Length = 555
           
 Score =  566 bits (1444), Expect = e-160
 Identities = 280/555 (50%), Positives = 378/555 (67%), Gaps = 13/555 (2%)

Query: 6   IHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDLYRKKP 65
           +H+ GIVQ VGFRPF+Y++A A+ L GYV+NLG+  VEI++EG  E ++ FL++L  KKP
Sbjct: 8   LHITGIVQGVGFRPFIYQLAKANGLSGYVKNLGNY-VEILIEGDRECLDNFLKELPEKKP 66

Query: 66  PIAKIEKVEREEIPIQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDPTNKRY 125
           P+AKI ++  + +P  G+  F I  S  E     +SIIPPD AICE C  E+FDP+++ Y
Sbjct: 67  PLAKITELRTKNVPFSGYSGFIIVPS--ESGVFENSIIPPDTAICEQCRSEIFDPSSRYY 124

Query: 126 MYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPVACPVC 185
            YPF VCTNCGPR+T +  LPYDRENT M +FP+C  C+ EY DPLNRRYHA+PV CP C
Sbjct: 125 HYPFTVCTNCGPRYTTVRTLPYDRENTTMADFPLCPECEKEYTDPLNRRYHAQPVCCPKC 184

Query: 186 GPSYRLYTSDGKEITG--DPLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVVAELRKR 243
           GP   L   +G  ++   + +  A+ L+ +G I+A+KG GG H+AC+A +E+ V ELR+R
Sbjct: 185 GPEIWLSDREGNVLSRGYEAIASASDLLQEGSILAVKGFGGFHIACNARQEEPVNELRRR 244

Query: 244 LFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKREPFPLPENLAPGLHT 303
           L RP++PFA+MAK+    + FA +     E LTS+RRPI  L + E F L ++++PGLH 
Sbjct: 245 LKRPEQPFAVMAKNAGVAESFADLEGAGREYLTSHRRPITVLPRSEEFNLADSVSPGLHN 304

Query: 304 IGVMLPYAGTHYILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEKLKDVADYLLLHNRRI 363
           IGVMLPY GT  +LF      VYVMTSAN PG PM+ DN EA EKLK + D+ LLHNR I
Sbjct: 305 IGVMLPYTGTQNLLFDRVPDAVYVMTSANLPGRPMVVDNREALEKLKGIVDFYLLHNRVI 364

Query: 364 PNRADDSVVRFVDGRRAVIRRSRGFVPLWIEIPFEYK-GLAVGAELMNAFGVAKNGKVYP 422
            NR DD+V+R V+G+ A IRRSRG+VP  +E+PFE +  + VGAE+ +   VAK    Y 
Sbjct: 365 ANRNDDTVIRIVNGQAAFIRRSRGYVPEPVELPFEIEASIGVGAEMNSTVTVAKGKLAYI 424

Query: 423 SQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPNYNTTKLAMEIAEEFNAEF 482
           SQYIGNTS +E   +  E ++H  ++  I  L     DLHP++NTT+ A+++  E     
Sbjct: 425 SQYIGNTSHVETYRYHSEVVRHLIRLTGIEPLHW-SCDLHPSFNTTRFALKMGGE---NT 480

Query: 483 LQVQHHYAHVASVMAEHNL---EEVVGIALDGVGYGTDGKTWGGEIIYLSYEDIERLAHL 539
           L++QHHYAH+ ++MA+++L     ++GIALDGVGYG DG  WGGE+   SY   ER+ HL
Sbjct: 481 LKIQHHYAHMLALMADNSLPLGSRILGIALDGVGYGGDGTIWGGELFESSYFGYERIGHL 540

Query: 540 EYYPLPGGDLASYYP 554
              P+PGGDLAS  P
Sbjct: 541 LPQPMPGGDLASRVP 555


>pir||B70359 transcription regulator HypF - Aquifex aeolicus
           >gi|2983269|gb|AAC06863.1| (AE000701) transcriptional
           regulatory protein HypF [Aquifex aeolicus]
           Length = 746
           
 Score =  558 bits (1422), Expect = e-158
 Identities = 330/762 (43%), Positives = 449/762 (58%), Gaps = 28/762 (3%)

Query: 2   KAYRIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDLY 61
           K  ++H++G VQ VGFRPFVYRIA    L+G+V N    GV I VEG EE ++ FL  L 
Sbjct: 4   KRLKLHLKGAVQGVGFRPFVYRIAKELGLKGFVIN-DSKGVYIEVEGEEERLKKFLFKLN 62

Query: 62  RKKPPIAKIEKVEREEIPIQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDPT 121
           R+KPP+A+I   E + +    ++ F I KS  E+KGE + ++ PDIA CEDCLRELF P 
Sbjct: 63  REKPPLARIYSQEIQFLEPVNYEDFVIRKS--EEKGEKEVLVLPDIATCEDCLRELFTPE 120

Query: 122 NKRYMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPVA 181
           ++RYMYPFI CTNCGPRFTIIE LPYDR+NT M+ F MC  CK EYE+PL+RR+HA+P A
Sbjct: 121 DRRYMYPFINCTNCGPRFTIIERLPYDRKNTTMKVFEMCPECKREYENPLDRRFHAQPNA 180

Query: 182 CPVCGPSYRLYTSDGKEIT--GDPLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVVAE 239
           CP CGP   LY  DGK I    + L    + I  G I+A+KG+GG HL C+AT E+ V  
Sbjct: 181 CPKCGPWVSLY-KDGKLIAEKNEALELLIEEIKIGKIVAVKGVGGFHLICNATNEESVRT 239

Query: 240 LRKRLFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKREPFPLPENLAP 299
           LRKR  R +KPFA+M K LE V+ +A  +  E+  L S  RPIV ++K++   L  +++P
Sbjct: 240 LRKRKRRSEKPFAVMFKSLEQVEAYANPTELEKALLISPERPIVLIQKKK--ELAPSVSP 297

Query: 300 GLHTIGVMLPYAGTHYILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEKLKDVADYLLLH 359
           GL  +G  LPY+  H+++ +    PV V TSAN    P+IKDN+EA EKL ++AD +L+H
Sbjct: 298 GLKRVGAFLPYSPLHHLILNSLDFPV-VATSANISEEPIIKDNKEALEKLGELADLILVH 356

Query: 360 NRRIPNRADDSVVRFVDGRRAVIRRSRGFVPLWIEIPFEY--KGLAVGAELMNAFGVAKN 417
           NR I  R DDSVV+ V G    IRRSRG+ PL +E+PFE   + LAVG  L N F +   
Sbjct: 357 NRDIKRRCDDSVVKVVSGVPTPIRRSRGYAPLPVEVPFELPKRVLAVGGMLKNTFALGFK 416

Query: 418 GKVYPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPNYNTTKLAMEIAEE 477
            +V  SQ+IG+   +  L+   E++    ++      D+VV D+HP Y TT+ A E + +
Sbjct: 417 NQVILSQHIGDIENLNTLKVFEESVFDLMELYEFEP-DVVVCDMHPRYETTRWAEEFSRK 475

Query: 478 FNAEFLQVQHHYAHVASVMAEHNL-EEVVGIALDGVGYGTDGKTWGGEIIYLSYEDIERL 536
                ++VQHHYAH+ S MAE+ + E+V+GIA DG GYG DG  WGGE +   Y   ER 
Sbjct: 476 RGIPLIKVQHHYAHMLSCMAENGIKEKVLGIAWDGTGYGEDGTLWGGEFLVADYTSYERA 535

Query: 537 AHLEYYPLPGGDLASYYPLRALIGILSLNHEIEEVENTIRKFCPNAIKSLKYGETELKVI 596
            + +   L GG+ A   P R     LSL  +I   E       P  +KS  + E ELK +
Sbjct: 536 FNFKPVKLIGGEKAVKEPRRV---ALSLLFDIFGEEALNLDLLP--VKS--FSERELKNL 588

Query: 597 LRQLSSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLESFASQGKNDLKLTIPV 656
                 GIN   +SS GR+ DA + LLN+     YEG+ AM +E        D      +
Sbjct: 589 YLAWKKGINSPLSSSVGRLFDALASLLNLKQILSYEGQGAMMVEDLYDPLVKD-NYPYEI 647

Query: 657 EGEEIRVSELFEEVLDLMGKASPRDIAYSIHLALARVFAEVSVEKAKEFGAKTVVLGGGV 716
            G+E+ + + F EVL    K   + +A S         A+V  + A   G + V L GGV
Sbjct: 648 RGKEVDLRKAFLEVL----KEKDKSLAAS---RFINTLAKVCEDIALMVGIERVCLSGGV 700

Query: 717 GYNELIVKTVRKIVEGNGLKFLTTYEVPRGDNGINVGQAFLG 758
             N+ +V  +++++E    K  T  +VP  D GI +GQA  G
Sbjct: 701 MQNDPLVTKIKELLEKEKFKVYTHQKVPPNDGGIALGQAVFG 742


>sp|O07451|HYF2_ALCEU HYDROGENASE MATURATION PROTEIN HYPF2 >gi|2183281|gb|AAB60890.1|
           (AF002655) HypF2 [Ralstonia eutropha]
           Length = 806
           
 Score =  467 bits (1188), Expect = e-130
 Identities = 301/800 (37%), Positives = 411/800 (50%), Gaps = 63/800 (7%)

Query: 5   RIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREED-IEGFLRDLYRK 63
           RI V+G+VQ VGFRPFVYR+A    L G+VRN G AGV+I  +G     ++  LR L R 
Sbjct: 16  RIRVRGVVQGVGFRPFVYRLARELGLAGWVRNDG-AGVDIEAQGSAAALVDSRLRRLRRD 74

Query: 64  KPPIAKIEKVEREEIPIQ-GFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDPTN 122
            PP+A+++++  E    Q   D F I +SS        + I  D A+C DCL ELFDP N
Sbjct: 75  APPLARVDEIGEERCAAQVDADGFAILESSRSDAAV-HTAIGHDTAVCPDCLAELFDPAN 133

Query: 123 KRYMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPVAC 182
           +RY Y FI CT CGPR+T+   LPYDR  T+M  FP C  C  EY DP +RR+HAEP AC
Sbjct: 134 RRYRYAFINCTQCGPRYTLTWALPYDRATTSMAPFPQCRPCLDEYNDPEHRRFHAEPNAC 193

Query: 183 PVCGPSYRLYTSDGKEITG-DPLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVVAELR 241
           P CGPS  L  + G  +   DP+ +    + +G I+AIKG+GG HLACDA   D VA LR
Sbjct: 194 PDCGPSLALLNAQGMPVEDVDPIAETVARLQRGEIVAIKGLGGFHLACDAHNADAVARLR 253

Query: 242 KRLFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKREPFPLPENLAPGL 301
            R  R +KPFA+M  +L T   +  I   E   LT+  RPIV LRK         +APGL
Sbjct: 254 SRKQREEKPFAVMVANLATAAQWGDIGSGEAALLTASERPIVLLRKHGVDGRFAGVAPGL 313

Query: 302 HTIGVMLPYAGTHYILFH----------WSKTP---VYVMTSANFPGMPMIKDNEEAFEK 348
             +GVMLPY    Y+LFH          W   P   V VMTSAN  G P++  N+E  ++
Sbjct: 314 VWLGVMLPYTPLQYLLFHEAAGRPEGLGWLAQPQSLVLVMTSANPGGEPLVTGNDETAQR 373

Query: 349 LKDVADYLLLHNRRIPNRADDSVVRFVDGRRA----VIRRSRGFVPLWIEIPFEYKG-LA 403
           L  +AD  LLH+R I  R DDSVVR  DG  A     IRR+RG+ P  I++       LA
Sbjct: 374 LTGIADAFLLHDREILVRCDDSVVR-GDGEPAPHVQFIRRARGYTPRAIKLARSGPSVLA 432

Query: 404 VGAELMNAFGVAKNGKVYPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHP 463
           +G    N   + +  + + SQ++G+       E + EA+ H  ++L I    LV  DLHP
Sbjct: 433 LGGSFKNTVCLTRGDEAFVSQHVGDLGNAATCEALIEAVAHLQRVLEIRP-QLVAHDLHP 491

Query: 464 NYNTTKLAMEIAEEFNAEFLQVQHHYAHVASVMAEHNLEE-VVGIALDGVGYGTDGKTWG 522
           ++ +T+ A E+A ++    + VQHH+AH+A+V+AEH  +E  +G+ALDGVG G DG+ WG
Sbjct: 492 DFFSTRHAAELAAQWGVPAVAVQHHHAHIAAVLAEHGSDEPAIGLALDGVGLGDDGQAWG 551

Query: 523 GEIIYLSYEDIERLAHLEYYPLPGGDLASYYPLRALIGILSLNHEIEEVENTIRKFCPNA 582
           GE        +     L   PLPGGD A+  P R     L      EE+E    +     
Sbjct: 552 GETAAGGRRRLLAPRSLARLPLPGGDRAAREPWRMAAAALHAMGRGEEIEGRFPR----- 606

Query: 583 IKSLKYGETELKVILRQLSSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLESF 642
                  +    ++ R L+  +N   +SS GR  DA + LL       YEG+ AM LE  
Sbjct: 607 -------QPGAPMVNRMLAQRLNAPLSSSMGRWFDAAAGLLGTRETMAYEGQAAMLLEGL 659

Query: 643 A-------SQGKNDLKL----TIPVEGEEIRVSELFE-------EVLDLM-------GKA 677
           A       S G+          +P  G   +   L +         LDL+        + 
Sbjct: 660 AESWGEQPSPGRPKTVAHSLGGVPRRGGTYKALALPDAWRIDAGNTLDLLPLLEALSAEN 719

Query: 678 SPRDIAYSIHLALARVFAEVSVEKAKEFGAKTVVLGGGVGYNELIVKTVRKIVEGNGLKF 737
             R      H  L       +V   +  G +TVV GGG   N ++ + + + +   GL  
Sbjct: 720 ECRARRSQFHATLVAALEAWTVATVQVTGVRTVVFGGGCFLNHILARNLCRRLAARGLTV 779

Query: 738 LTTYEVPRGDNGINVGQAFL 757
           LT  ++P  D GI +GQ ++
Sbjct: 780 LTARQLPPNDGGIALGQVWV 799


>sp|P40596|HYPF_AZOVI HYDROGENASE MATURATION PROTEIN HYPF
           Length = 776
           
 Score =  457 bits (1164), Expect = e-127
 Identities = 289/783 (36%), Positives = 413/783 (51%), Gaps = 62/783 (7%)

Query: 5   RIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDLYRKK 64
           R+ ++G VQ VG RP V+R+A +  L G VRN G AGV I + G  + +  F R L  + 
Sbjct: 10  RLLLRGRVQGVGMRPCVHRLATSLGLAGEVRNTG-AGVRIDLLGPPQALAEFERRLPDEL 68

Query: 65  PPIAKIEKVEREEIPI-QGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDPTNK 123
           PP+A+++ ++RE +P    F  F I  S  E++G      PPD A+C  CL ELFDP ++
Sbjct: 69  PPLARLDAIQREPLPAGTRFAGFAIAASRDERRGA--LAPPPDAAVCPACLEELFDPHDR 126

Query: 124 RYMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPVACP 183
           R+ +PFI CT+CGPR+++I  LPYDR  T++  F +C  C+ EYEDP +RR+HA+P+ACP
Sbjct: 127 RWRHPFINCTHCGPRYSLIRRLPYDRVQTSLAGFELCPECRREYEDPADRRFHAQPIACP 186

Query: 184 VCGPSYRLYTSDGKEITGDPLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVVAELRKR 243
            CGP      + G+ ++GDP+ +A   + +G I+A++G+GG HLACDA     VAELR+R
Sbjct: 187 ACGPRLCCEDASGRRLSGDPIERALAALARGEILALRGVGGFHLACDARNAGAVAELRRR 246

Query: 244 LFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKREPFP--LPENLAPGL 301
             RP KPFA+MA +  +++    ++     EL+    P+V LRKR      L   +AP L
Sbjct: 247 KRRPAKPFALMAANPASLQALVELNENGLAELSGPAAPVVLLRKRPAADDLLAAGVAPDL 306

Query: 302 HTIGVMLPYAGTHYILFH----------WSKTP---VYVMTSANFPGMPMIKDNEEAFEK 348
             +G MLP++  H++LFH          W+  P   + VMTSAN  G P I  N EA E+
Sbjct: 307 AWLGAMLPHSPLHWLLFHEAAGRPAGTGWAAAPQDLLLVMTSANLSGAPPITGNAEARER 366

Query: 349 LKDVADYLLLHNRRIPNRADDSVVRFVDGRRAVIRRSRGFVPLWIEIPFEYKG---LAVG 405
           L  +AD  LLH+R I NR DDSVV  +     VIR  RG  PL  EIP    G   LA+G
Sbjct: 367 LAGIADLWLLHDREILNRCDDSVVSALGRAPLVIRSGRGLAPL--EIPLARGGPSILALG 424

Query: 406 AELMNAFGVAKNGKVYPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPNY 465
            +L NA  + +  + + S + G+    +    +   +    ++L I   + V  DLHP++
Sbjct: 425 GQLKNAVCLTRGDRAWLSPHNGDLDDADTCRALERTVARLGELLGIRP-ERVACDLHPDF 483

Query: 466 NTTKLAMEIAEEFNAEFLQVQHHYAHVASVMAEHNL-EEVVGIALDGVGYGTDGKTWGGE 524
             ++ A + AE        +QHH+AH+A+ MAEH L E V+G+ALDG G G DG+  GGE
Sbjct: 484 FASRFARDYAERHGLPLHPIQHHHAHIAATMAEHGLAEPVLGLALDGFGLGADGRLRGGE 543

Query: 525 IIYLSYEDIERLAHLEYYPLPGGDLASYYPLRALIGILSLNHEIEEVENTIRKFCPNAIK 584
           ++ ++ +    L  L   PLPGGD AS  P R   G L   H +        +F      
Sbjct: 544 LLRVAADGCAWLGELNPLPLPGGDQASREPWRMAAGAL---HALGRGGEIATRFA----- 595

Query: 585 SLKYGETELKVILRQLSSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLESFAS 644
                E     I R L  G N   +SS GR+ DA + LL +  R+ YE E A++LES   
Sbjct: 596 ----AEPGNAAIARMLERGFNCPPSSSAGRLFDAAAGLLGLGGRQRYEAEAALRLES--- 648

Query: 645 QGKNDLKLTIPVEGEEIRVSELFE-------EVLDLMGK-ASPRDI---AYSIHLALARV 693
                      V G   RV  L+        ++L L+ + A  RD    A   H  L   
Sbjct: 649 ----------RVVGLPERVPALWRIDDDNRLDLLPLLARLADMRDTRAGAELFHGVLIEA 698

Query: 694 FAEVSVEKAKEFGAKTVVLGGGVGYNELIVKTVRKIVEGNGLKFLTTYEVPRGDNGINVG 753
            A  +   A+  G   V LGGG   N ++   +   +   GL  L     P  D G+ +G
Sbjct: 699 LAIWAARAAEATGLHRVALGGGCFLNTVLRDGLCARLRAAGLTPLLARRAPLNDGGLALG 758

Query: 754 QAF 756
           QA+
Sbjct: 759 QAW 761


>sp|Q43950|HYPF_AZOCH HYDROGENASE MATURATION PROTEIN HYPF
           Length = 776
           
 Score =  447 bits (1138), Expect = e-124
 Identities = 273/773 (35%), Positives = 411/773 (52%), Gaps = 40/773 (5%)

Query: 5   RIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDLYRKK 64
           R+ ++G VQ VG RP V+R+A +  L G V N G+ GV I ++G    +  F R L  + 
Sbjct: 10  RLLLRGRVQGVGMRPGVHRLATSLGLAGAVCNTGE-GVRIDLQGPPAALAEFERRLPAEL 68

Query: 65  PPIAKIEKVEREEIPIQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDPTNKR 124
           PP+A+++ ++RE +P       +    S ++ G G    PPD A+C  CL ELFDP ++R
Sbjct: 69  PPLARLDALQRENLPAGAHFAGFAIVPSRDEAG-GALAPPPDAAVCPACLEELFDPHDRR 127

Query: 125 YMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPVACPV 184
           + +PFI CT+CGPR+++I  LPYDR  T++  F +C  C+ EYEDP +RR+HA+P+ACP 
Sbjct: 128 WRHPFINCTHCGPRYSLIRRLPYDRAQTSLAGFALCPDCRHEYEDPADRRFHAQPIACPA 187

Query: 185 CGPSYRLYTSDGKEITGDPLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVVAELRKRL 244
           CGP      + G  + G+P+  A   + +G I+A++G+GG HLACDA     VA LR+R 
Sbjct: 188 CGPRLWCEDAAGNRLPGEPVELALATLRRGEIVALRGVGGFHLACDARNAGAVALLRRRK 247

Query: 245 FRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKREPFP--LPENLAPGLH 302
            RP KPFA+MA +  +++    ++     EL++   P+V LR+R      L   +AP L 
Sbjct: 248 RRPAKPFALMAANPASLEALVELNETGLNELSAPAAPVVLLRRRPAADGLLAAEVAPDLA 307

Query: 303 TIGVMLPYAGTHYILFH----------WSKTP---VYVMTSANFPGMPMIKDNEEAFEKL 349
            +GVMLP++  H++LFH          W+  P   V VMTSAN  G P+I  N EA EKL
Sbjct: 308 WLGVMLPHSPLHWLLFHEAAGRPAGTAWTAAPQDLVLVMTSANLSGEPLITGNLEAREKL 367

Query: 350 KDVADYLLLHNRRIPNRADDSVVRFVDGRRAVIRRSRGFVPLWIEIPFEYKG---LAVGA 406
             + D  LLH+R I NR DDS+V  +     VIR  RG  P   EI     G   LA+G 
Sbjct: 368 AGITDLWLLHDREILNRVDDSLVNALGRAPVVIRSGRGLAPQ--EIRLARSGPSVLALGG 425

Query: 407 ELMNAFGVAKNGKVYPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPNYN 466
           +L NA  + +  + + S +IG+    +    +   +  F ++L +   + +  DLHP++ 
Sbjct: 426 QLKNAICLTQGDRAWLSPHIGDLHSADACRSLERTVAQFGELLGVRP-ERIACDLHPDFF 484

Query: 467 TTKLAMEIAEEFNAEFLQVQHHYAHVASVMAEHNL-EEVVGIALDGVGYGTDGKTWGGEI 525
            ++ A E AE        VQHH+AH+A+V+AEH L E V+G+ALDG G G DG+  GGE+
Sbjct: 485 ASRFAREHAERHGLPLYPVQHHHAHIAAVLAEHGLAEPVLGLALDGFGLGADGRLRGGEL 544

Query: 526 IYLSYEDIERLAHLEYYPLPGGDLASYYPLRALIGILSLNHEIEEVENTIRKFCPNAIKS 585
           + ++ +    L  L   PLPGGD A+  P R   G L   H +        +F       
Sbjct: 545 LKVAVDGCAWLGELNPLPLPGGDQAAREPWRMAAGAL---HALGRGGEIATRFA------ 595

Query: 586 LKYGETELKVILRQLSSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLES-FAS 644
               E     I R L  G N   +SS GR+ DA + LL +  R+ YE E A++LES   S
Sbjct: 596 ---AEPGSAAIARMLERGFNCPPSSSAGRLFDAAAGLLGLGERQRYEAEAALRLESRIGS 652

Query: 645 QGKNDLKLTIPVEGEEIRVSELFEEVLDLMGKASPRDIAYSIHLALARVFAEVSVEKAKE 704
             +    L    +   + +S L   + D        ++ +++ +A    +    V  A  
Sbjct: 653 LPEAVPPLWRIGDDNRLDLSPLLARLADTHDSRVGAELFHAVLIAALTAWV---VRAAAA 709

Query: 705 FGAKTVVLGGGVGYNELIVKTVRKIVEGNGLKFLTTYEVPRGDNGINVGQAFL 757
            G + + LGGG   N ++   +   ++  GL+ L     P  D G+ +GQA++
Sbjct: 710 TGLRRIALGGGCFLNTVLRDGLCTRLQAAGLEPLLPRRAPVNDGGLALGQAWV 762


>pir||S23441 hypothetical protein 6 - Azotobacter vinelandii
           >gi|39243|emb|CAA45185.1| (X63650) ORF6 [Azotobacter
           vinelandii] >gi|398009|gb|AAA19510.1| (L23970) hypF
           [Azotobacter vinelandii]
           Length = 755
           
 Score =  446 bits (1136), Expect = e-124
 Identities = 283/770 (36%), Positives = 404/770 (51%), Gaps = 62/770 (8%)

Query: 18  RPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDLYRKKPPIAKIEKVEREE 77
           RP V+R+A +  L G VRN G AGV I + G  + +  F R L  + PP+A+++ ++RE 
Sbjct: 2   RPCVHRLATSLGLAGEVRNTG-AGVRIDLLGPPQALAEFERRLPDELPPLARLDAIQREP 60

Query: 78  IPI-QGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDPTNKRYMYPFIVCTNCG 136
           +P    F  F I  S  E++G      PPD A+C  CL ELFDP ++R+ +PFI CT+CG
Sbjct: 61  LPAGTRFAGFAIAASRDERRGA--LAPPPDAAVCPACLEELFDPHDRRWRHPFINCTHCG 118

Query: 137 PRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPVACPVCGPSYRLYTSDG 196
           PR+++I  LPYDR  T++  F +C  C+ EYEDP +RR+HA+P+ACP CGP      + G
Sbjct: 119 PRYSLIRRLPYDRVQTSLAGFELCPECRREYEDPADRRFHAQPIACPACGPRLCCEDASG 178

Query: 197 KEITGDPLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVVAELRKRLFRPQKPFAIMAK 256
           + ++GDP+ +A   + +G I+A++G+GG HLACDA     VAELR+R  RP KPFA+MA 
Sbjct: 179 RRLSGDPIERALAALARGEILALRGVGGFHLACDARNAGAVAELRRRKRRPAKPFALMAA 238

Query: 257 DLETVKGFAYISREEEEELTSYRRPIVALRKREPFP--LPENLAPGLHTIGVMLPYAGTH 314
           +  +++    ++     EL+    P+V LRKR      L   +AP L  +G MLP++  H
Sbjct: 239 NPASLQALVELNENGLAELSGPAAPVVLLRKRPAADDLLAAGVAPDLAWLGAMLPHSPLH 298

Query: 315 YILFH----------WSKTP---VYVMTSANFPGMPMIKDNEEAFEKLKDVADYLLLHNR 361
           ++LFH          W+  P   + VMTSAN  G P I  N EA E+L  +AD  LLH+R
Sbjct: 299 WLLFHEAAGRPAGTGWAAAPQDLLLVMTSANLSGAPPITGNAEARERLAGIADLWLLHDR 358

Query: 362 RIPNRADDSVVRFVDGRRAVIRRSRGFVPLWIEIPFEYKG---LAVGAELMNAFGVAKNG 418
            I NR DDSVV  +     VIR  RG  PL  EIP    G   LA+G +L NA  + +  
Sbjct: 359 EILNRCDDSVVSALGRAPLVIRSGRGLAPL--EIPLARGGPSILALGGQLKNAVCLTRGD 416

Query: 419 KVYPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPNYNTTKLAMEIAEEF 478
           + + S + G+    +    +   +    ++L I   + V  DLHP++  ++ A + AE  
Sbjct: 417 RAWLSPHNGDLDDADTCRALERTVARLGELLGIRP-ERVACDLHPDFFASRFARDYAERH 475

Query: 479 NAEFLQVQHHYAHVASVMAEHNL-EEVVGIALDGVGYGTDGKTWGGEIIYLSYEDIERLA 537
                 +QHH+AH+A+ MAEH L E V+G+ALDG G G DG+  GGE++ ++ +    L 
Sbjct: 476 GLPLHPIQHHHAHIAATMAEHGLAEPVLGLALDGFGLGADGRLRGGELLRVAADGCAWLG 535

Query: 538 HLEYYPLPGGDLASYYPLRALIGILSLNHEIEEVENTIRKFCPNAIKSLKYGETELKVIL 597
            L   PLPGGD AS  P R   G L   H +        +F           E     I 
Sbjct: 536 ELNPLPLPGGDQASREPWRMAAGAL---HALGRGGEIATRFA---------AEPGNAAIA 583

Query: 598 RQLSSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLESFASQGKNDLKLTIPVE 657
           R L  G N   +SS GR+ DA + LL +  R+ YE E A++LES              V 
Sbjct: 584 RMLERGFNCPPSSSAGRLFDAAAGLLGLGGRQRYEAEAALRLES-------------RVV 630

Query: 658 GEEIRVSELFE-------EVLDLMGK-ASPRDI---AYSIHLALARVFAEVSVEKAKEFG 706
           G   RV  L+        ++L L+ + A  RD    A   H  L    A  +   A+  G
Sbjct: 631 GLPERVPALWRIDDDNRLDLLPLLARLADMRDTRAGAELFHGVLIEALAIWAARAAEATG 690

Query: 707 AKTVVLGGGVGYNELIVKTVRKIVEGNGLKFLTTYEVPRGDNGINVGQAF 756
              V LGGG   N ++   +   +   GL  L     P  D G+ +GQA+
Sbjct: 691 LHRVALGGGCFLNTVLRDGLCARLRAAGLTPLLARRAPLNDGGLALGQAW 740


>sp|P28156|HYPF_RHILV HYDROGENASE MATURATION PROTEIN HYPF >gi|420902|pir||S32875 hypF
           protein - Rhizobium leguminosarum bv. viciae
           >gi|48734|emb|CAA37161.1| (X52974) HypF product contains
           two putative metal-binding motifs CxxC-x18-CxxC
           separated by 24 aa residues and arranged as 'zinc
           fingers' [Rhizobium leguminosarum]
           Length = 759
           
 Score =  440 bits (1119), Expect = e-122
 Identities = 274/762 (35%), Positives = 400/762 (51%), Gaps = 45/762 (5%)

Query: 1   MKAYRIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDL 60
           ++  R+ V+G VQ VGFRPF YR+A A  L G+V N   AGV I +EGR  D   F   +
Sbjct: 13  VRRLRLRVRGAVQGVGFRPFAYRLARAMRLSGFVLN-DSAGVLIEIEGR--DANHFPEAV 69

Query: 61  YRKKPPIAKIEKVEREEIPIQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDP 120
             + PP+A+I+ ++  E+   G +RF I +S     G   + I  D A C+ C REL DP
Sbjct: 70  RTQAPPLARIDSIDVLELVPAGGERFEILESLG---GRSATRIGADAATCDGCRRELTDP 126

Query: 121 TNKRYMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPV 180
            ++ + YPF+ CT+CGPRFTI   LPYDR +T+M  FPMC  C ++Y DP NRR+HAEPV
Sbjct: 127 ASRFFGYPFVNCTHCGPRFTITRALPYDRAHTSMASFPMCRTCAADYVDPENRRFHAEPV 186

Query: 181 ACPVCGPSYRLYTSDGKEITGDPLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVVAEL 240
           ACP CGP               P+++ +  ++ G I+A+KG+GG HL CDA  +  +  L
Sbjct: 187 ACPNCGPR-----------LSHPIKEISARLEGGAIVALKGVGGFHLLCDARNDGAIGLL 235

Query: 241 RKRLFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKREPFPLPENLAPG 300
           R R    QKPFA+M +D+E  +  A  +  EE  L S  RPIV +  R    L   +APG
Sbjct: 236 RLRKAGDQKPFAVMVRDIEAARQLARPNEAEEALLISPARPIVLVAARAG-ELSGLIAPG 294

Query: 301 LHTIGVMLPYAGTHYILF-HWSKTPVY-----VMTSANFPGMPMIKDNEEAFEKLKDVAD 354
           L  +G+ML YA  H++L    S++  +     V TSAN  G P++ DN++A  +L  +AD
Sbjct: 295 LTRVGLMLAYAPVHHLLLDELSRSSPHCHAALVATSANPGGEPLVADNDDAGRRLVAIAD 354

Query: 355 YLLLHNRRIPNRADDSVVRFVDGRRAVIRRSRGFVPLWIEIPFEYKG-LAVGAELMNAFG 413
            ++ H+R I  RADDSV++ +DG  A IRR+RGFVP  +++  +    +A GA+L N   
Sbjct: 355 LVVTHDRDIVVRADDSVMQVIDGAPAFIRRARGFVPEPVDLGADGPSVIATGADLKNTIC 414

Query: 414 VAKNGKVYPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPNYNTTKLAME 473
           V +  + + SQ+IG     E + F RE I H   IL +   +    DLHP++ + +    
Sbjct: 415 VTRGREAFLSQHIGGLDNAEAIRFQREVIAHLCSILDVKP-EFAACDLHPDFRSVR---- 469

Query: 474 IAEEFNAEFLQVQHHYAHVASVMAEHNLE-EVVGIALDGVGYGTDGKTWGGEIIYLSYED 532
            AE  N   + VQHH AHVA+V+A+  L   V+G+ALDG G+GTDG +WGGEI+ + +  
Sbjct: 470 TAEGLNLPIVPVQHHLAHVAAVVADDRLSGPVLGLALDGHGFGTDGTSWGGEIVVIDHHR 529

Query: 533 IERLAHLEYYPLPGGDLASYYPLRALIGILSLNHEIEEVENTIRKFCPNAIKSLKYGETE 592
            +R   L   PLP GD A+  P R  +  L     I+                L  G + 
Sbjct: 530 WQRAGSLMPLPLPSGDRAAREPWRMGVAALQAAGRID------------LAPQLWPGHSG 577

Query: 593 LKVILRQLSSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLESFASQGKNDLKL 652
           +  +    S  +     SS GR+ DA + +  V   + YEG+ AM+ E+   +    L  
Sbjct: 578 VTQLTAMFSGSMPTPVTSSLGRLFDAAAAIAGVRLVQDYEGQAAMEFEALV-RAPRCLAG 636

Query: 653 TIPVEGEEIRVSELFEEVLDLMGKASPRDIAYSIHLALARVFAEVSVEKAKEFGAKTVVL 712
              +    +    L   + +  G+    D A   H  L    A+ +   A   G + V L
Sbjct: 637 GYSIGDGTLDFRPLILHLAE-QGRPCGADAADVFHGTLIAGLADWAARGAAARGTRQVAL 695

Query: 713 GGGVGYNELIVKTVRKIVEGNGLKFLTTYEVPRGDNGINVGQ 754
           GGG   N ++   + + +   GL+       P  D GI +GQ
Sbjct: 696 GGGCMMNRVLAAGLARALRERGLEPSLPRLAPANDGGIALGQ 737


>sp|Q55638|HYPF_SYNY3 HYDROGENASE MATURATION PROTEIN HYPF >gi|7449693|pir||S76302
           hypothetical protein - Synechocystis sp. (strain PCC
           6803) >gi|1001527|dbj|BAA10154.1| (D64000)
           transcriptional regulatory protein HypF [Synechocystis
           sp.]
           Length = 767
           
 Score =  437 bits (1113), Expect = e-121
 Identities = 276/769 (35%), Positives = 403/769 (51%), Gaps = 30/769 (3%)

Query: 1   MKAYRIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDL 60
           +K   I VQG VQ VGFRPFVY +A    L G+V N    G  +V+   E+ I  F   L
Sbjct: 2   LKTVAIQVQGRVQGVGFRPFVYTLAQEMGLNGWVNN-STQGATVVITADEKAIADFTERL 60

Query: 61  YRKKPPIAKIEKVEREEIPIQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDP 120
            +  PP   IE++  E++P++ F  F I  SS    G   + I PD++ C  CL ELFDP
Sbjct: 61  TKTLPPPGLIEQLAVEQLPLESFTNFTIRPSSD---GPKTASILPDLSTCSACLTELFDP 117

Query: 121 TNKRYMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPV 180
           +++RY+YPFI CT+CGPR+TIIE LPYDR  T M  F  C  C+ EY+ P +RR+HA+P 
Sbjct: 118 SDRRYLYPFINCTHCGPRYTIIEALPYDRCRTTMARFRQCTDCEREYKQPGDRRFHAQPN 177

Query: 181 ACPVCGPSYRLYTSDGKEI--TGDPLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVVA 238
           ACP CGP    +   G+ I    + L  A   +  G IIAIKG+GG HL CDAT  + V 
Sbjct: 178 ACPRCGPQLAFWNRQGQVIAEANEALNFAVDNLKVGNIIAIKGLGGFHLCCDATDFEAVE 237

Query: 239 ELRKRLFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKREPFPLPENLA 298
           +LR R  RP KP A+M  +L  +      +  E E L S   PIV L K++   L EN+A
Sbjct: 238 KLRLRKHRPDKPLAVMYGNLGQIVEHYQPNNLEVELLQSAAAPIVLLNKKKQLILVENIA 297

Query: 299 PGLHTIGVMLPYAGTHYILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEKLKDVADYLLL 358
           PG   +GVML Y   H++L    K P+ V TS N  G  +  DN +A  +L+++AD  L+
Sbjct: 298 PGNPRVGVMLAYTPLHHLLLKKLKKPM-VATSGNLAGEQICIDNIDALTRLQNIADGFLV 356

Query: 359 HNRRIPNRADDSVVRFVDGRRAVIRRSRGFVPLWIEI--PFEYKGLAVGAELMNAFGVAK 416
           H+R I    DDSVV+ V G+   +RR+RG+ P  I +  P + K LA+G    N   +AK
Sbjct: 357 HDRPIVCPVDDSVVQIVAGKPLFLRRARGYAPQPITLPKPTQKKLLAMGGHYKNTVAIAK 416

Query: 417 NGKVYPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPNYNTTKLAMEIAE 476
             + Y SQ++G+ +     +   EAI H  ++   +  + +VADLHP+Y     + + AE
Sbjct: 417 QNQAYVSQHLGDLNSAPTYQNFEEAIAHLSQLYDFSPQE-IVADLHPDY----FSHQYAE 471

Query: 477 EFNAEFLQVQHHYAHVASVMAEHNL--EEVVGIALDGVGYGTDGKTWGGEIIYLSYEDIE 534
                   VQHHYAH+ +VMAEH +  E V+GIA DG GYG DG  WGGE + ++    +
Sbjct: 472 NQALPVTFVQHHYAHILAVMAEHGVMEESVLGIAWDGTGYGMDGTIWGGEFLKITQGTWQ 531

Query: 535 RLAHLEYYPLPGGDLASYYPLRALIGIL----SLNHEIEEVEN--TIRKFCPNAIKSLKY 588
           R+AHL+ + L G   A  YP R  + +L      +   + + N         N I S   
Sbjct: 532 RIAHLQPFHLLGNQQAIKYPHRIALALLWPTFGDDFSADSLGNWLNFNNGFKNKINSRLN 591

Query: 589 GETELKVILRQLSSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLESFASQGKN 648
            +   K  LRQL         SS GR+ D  + L+ +     +EG+ A+ LE+       
Sbjct: 592 QDLNNK-NLRQLWQRGQAPLTSSMGRLFDGIATLIGLINEVTFEGQAAIALEAQIMPNLT 650

Query: 649 DLKLTIPVEGEEIRVSELFEEVLDLM---GKASPRDIAYSIHLALARVFAEVSVEKAKEF 705
           +    + +  +E +++  +  ++  +    ++    IA   H +L  +   +    A++ 
Sbjct: 651 EEYYPLTLNNKEKKLAVDWRPLIKAITTEDRSKTNLIATKFHNSLVNLIITI----AQQQ 706

Query: 706 GAKTVVLGGGVGYNELIVKTVRKIVEGNGLKFLTTYEVPRGDNGINVGQ 754
           G + V LGGG   N  ++ +    ++  G   L   E+P  D  I +GQ
Sbjct: 707 GIEKVALGGGCFQNCYLLASTITALKKAGFSPLWPRELPPNDGAICMGQ 755


>pir||JN0648 hydrogenase expression/formation protein HupY - Azotobacter
           chroococcum >gi|289236|gb|AAA22134.1| (L00674)
           hydrogenase accessory protein HupY [Azotobacter
           chroococcum]
           Length = 755
           
 Score =  436 bits (1110), Expect = e-121
 Identities = 267/760 (35%), Positives = 402/760 (52%), Gaps = 40/760 (5%)

Query: 18  RPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDLYRKKPPIAKIEKVEREE 77
           RP V+R+A +  L G V N G+ GV I ++G    +  F R L  + PP+A+++ ++RE 
Sbjct: 2   RPGVHRLATSLGLAGAVCNTGE-GVRIDLQGPPAALAEFERRLPAELPPLARLDALQREN 60

Query: 78  IPIQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDPTNKRYMYPFIVCTNCGP 137
           +P       +    S ++ G G    PPD A+C  CL ELFDP ++R+ +PFI CT+CGP
Sbjct: 61  LPAGAHFAGFAIVPSRDEAG-GALAPPPDAAVCPACLEELFDPHDRRWRHPFINCTHCGP 119

Query: 138 RFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPVACPVCGPSYRLYTSDGK 197
           R+++I  LPYDR  T++  F +C  C+ EYEDP +RR+HA+P+ACP CGP      + G 
Sbjct: 120 RYSLIRRLPYDRAQTSLAGFALCPDCRHEYEDPADRRFHAQPIACPACGPRLWCEDAAGN 179

Query: 198 EITGDPLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVVAELRKRLFRPQKPFAIMAKD 257
            + G+P+  A   + +G I+A++G+GG HLACDA     VA LR+R  RP KPFA+MA +
Sbjct: 180 RLPGEPVELALATLRRGEIVALRGVGGFHLACDARNAGAVALLRRRKRRPAKPFALMAAN 239

Query: 258 LETVKGFAYISREEEEELTSYRRPIVALRKREPFP--LPENLAPGLHTIGVMLPYAGTHY 315
             +++    ++     EL++   P+V LR+R      L   +AP L  +GVMLP++  H+
Sbjct: 240 PASLEALVELNETGLNELSAPAAPVVLLRRRPAADGLLAAEVAPDLAWLGVMLPHSPLHW 299

Query: 316 ILFH----------WSKTP---VYVMTSANFPGMPMIKDNEEAFEKLKDVADYLLLHNRR 362
           +LFH          W+  P   V VMTSAN  G P+I  N EA EKL  + D  LLH+R 
Sbjct: 300 LLFHEAAGRPAGTAWTAAPQDLVLVMTSANLSGEPLITGNLEAREKLAGITDLWLLHDRE 359

Query: 363 IPNRADDSVVRFVDGRRAVIRRSRGFVPLWIEIPFEYKG---LAVGAELMNAFGVAKNGK 419
           I NR DDS+V  +     VIR  RG  P   EI     G   LA+G +L NA  + +  +
Sbjct: 360 ILNRVDDSLVNALGRAPVVIRSGRGLAPQ--EIRLARSGPSVLALGGQLKNAICLTQGDR 417

Query: 420 VYPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPNYNTTKLAMEIAEEFN 479
            + S +IG+    +    +   +  F ++L +   + +  DLHP++  ++ A E AE   
Sbjct: 418 AWLSPHIGDLHSADACRSLERTVAQFGELLGVRP-ERIACDLHPDFFASRFAREHAERHG 476

Query: 480 AEFLQVQHHYAHVASVMAEHNL-EEVVGIALDGVGYGTDGKTWGGEIIYLSYEDIERLAH 538
                VQHH+AH+A+V+AEH L E V+G+ALDG G G DG+  GGE++ ++ +    L  
Sbjct: 477 LPLYPVQHHHAHIAAVLAEHGLAEPVLGLALDGFGLGADGRLRGGELLKVAVDGCAWLGE 536

Query: 539 LEYYPLPGGDLASYYPLRALIGILSLNHEIEEVENTIRKFCPNAIKSLKYGETELKVILR 598
           L   PLPGGD A+  P R   G L   H +        +F           E     I R
Sbjct: 537 LNPLPLPGGDQAAREPWRMAAGAL---HALGRGGEIATRFA---------AEPGSAAIAR 584

Query: 599 QLSSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLES-FASQGKNDLKLTIPVE 657
            L  G N   +SS GR+ DA + LL +  R+ YE E A++LES   S  +    L    +
Sbjct: 585 MLERGFNCPPSSSAGRLFDAAAGLLGLGERQRYEAEAALRLESRIGSLPEAVPPLWRIGD 644

Query: 658 GEEIRVSELFEEVLDLMGKASPRDIAYSIHLALARVFAEVSVEKAKEFGAKTVVLGGGVG 717
              + +S L   + D        ++ +++ +A    +    V  A   G + + LGGG  
Sbjct: 645 DNRLDLSPLLARLADTHDSRVGAELFHAVLIAALTAWV---VRAAAATGLRRIALGGGCF 701

Query: 718 YNELIVKTVRKIVEGNGLKFLTTYEVPRGDNGINVGQAFL 757
            N ++   +   ++  GL+ L     P  D G+ +GQA++
Sbjct: 702 LNTVLRDGLCTRLQAAGLEPLLPRRAPVNDGGLALGQAWV 741


>pir||E81410 transcription regulatory protein hypF Cj0622 [imported] -
           Campylobacter jejuni (strain NCTC 11168)
           >gi|6968089|emb|CAB75258.1| (AL139075) transcriptional
           regulatory protein hypF [Campylobacter jejuni]
           Length = 729
           
 Score =  433 bits (1101), Expect = e-120
 Identities = 269/763 (35%), Positives = 414/763 (54%), Gaps = 60/763 (7%)

Query: 4   YRIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDLYRK 63
           Y+I + G+VQ VGFRP VY +A    L G VRN G  GVEI++   +++ E F+ +L   
Sbjct: 6   YKIKISGLVQGVGFRPLVYELALKSKLFGEVRNDG-FGVEIILACTQKECENFIENLKNH 64

Query: 64  KPPIAKIEKVEREEIPIQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDPTNK 123
            PP+A+I+++   +I I  ++ F I  S    K    + +  D A C++C +E FD  N 
Sbjct: 65  LPPLARIDQLIITQISISNYENFSITPSLENTKS---TPMLSDFAFCKECKKEFFDEKNP 121

Query: 124 RYMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPVACP 183
           R++YPFI CT+CGPRF+II+ LPYDR +T+M+E  MC+FCKSEYEDP NRR+HA+P++CP
Sbjct: 122 RFLYPFITCTHCGPRFSIIKSLPYDRAHTSMQELLMCEFCKSEYEDPKNRRFHAQPISCP 181

Query: 184 VCGPSYRLYTSDGKEITGD--PLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVVAELR 241
            C  +  L    G+ +  D     ++AK + +G I+AIKGIGG HL CDA  E+ +  LR
Sbjct: 182 KCKINVFLKNPKGEILAKDQEAFMQSAKFLKEGKILAIKGIGGFHLMCDAFNEEALKTLR 241

Query: 242 KRLFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKREPFPLPENLAPGL 301
            R  RP+KPFA+M KDL++ K  A+I  +EE  L     PIV L+ ++ F L   +AP +
Sbjct: 242 LRKNRPKKPFALMCKDLQSAKELAFIDEKEEALLGGVLAPIVILKAKKAFSL---IAPDV 298

Query: 302 HTIGVMLPYAGTHYILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEKLKDVADYLLLHNR 361
             IG+ML Y   H +LF + K  + V TSAN  G  +IKD     +KL  V D+ L ++R
Sbjct: 299 DKIGIMLAYTPLHLLLFEYFKGSL-VATSANLSGESIIKDEFNLCKKLDKVFDFYLDYDR 357

Query: 362 RIPNRADDSVVRFVDGRRAVIRRSRGFVPLWIEIPFEYKG--LAVGAELMNAFGVAKNGK 419
            I N +DDS+ + V+G    +R SRG  P ++E  F  KG  LA+GAEL N F +    K
Sbjct: 358 EIINASDDSIAQVVNGETMFLRTSRGLNPFYLERNFNKKGTFLALGAELKNEFVIFYENK 417

Query: 420 VYPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPNYNTTKLAMEIAEEFN 479
           +  S YIG+   ++V E   + ++ FFK       D ++ D HP+++        A+EF 
Sbjct: 418 LLISPYIGDLKSLDVHERFFKLLE-FFKQNYDLKFDAILCDKHPHFS-------YAKEFE 469

Query: 480 AEFLQVQHHYAHVASVMAEHNL-----EEVVGIALDGVGYGTDGKTWGGEIIYLSYEDIE 534
            E +++ HHYAH  +   E+       E+ +    DG GYG DGK WGGE+   + ++ E
Sbjct: 470 -ERIKISHHYAHFCAAYFEYEENFAKDEKALAFICDGTGYGEDGKIWGGEVFVGNLKEYE 528

Query: 535 RLAHLEYYPLPGGDLASYYPLRALIGILSLNHEIEE-VENTIRKFCPNAIKSLK--YGET 591
           R+AH E + L   D+ +   ++ L   L  ++++E+  ++ + K     +K+LK  Y  +
Sbjct: 529 RIAHFENFTLINSDIKN---IQNLALSLIFHYDLEDKAKDFLAKIPKIKLKNLKKIYSHS 585

Query: 592 ELKVILRQLSSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLESFASQGKNDLK 651
            L+               SS GR++DAF  ++    +  YE +  +  E+F  +   D  
Sbjct: 586 NLQ--------------TSSLGRIIDAFGSIVFNLEKSSYEAQVGLMCEAFYDKNL-DFS 630

Query: 652 LTIPVEGEEIRVSELFEEVLDLMGKASPRDIAYSIHLALARVFAEVSVEKAKEFGAKTVV 711
             + VE  ++    L    L        +D        +    A   ++ +K++  K V+
Sbjct: 631 YKLFVEKGQVNFKNLILGAL--------QDEKTKAITGMFNALANFIIDFSKDYDLK-VL 681

Query: 712 LGGGVGYNELIVKTVRKIVEGNGLKFLTTYEVPRGDNGINVGQ 754
           L GGV  N    KT+ +I++     F    + P  D+ I +GQ
Sbjct: 682 LSGGVFQN----KTLLEILKAKNFDFFIPLKYPCNDSSIALGQ 720


>sp|P30131|HYPF_ECOLI HYDROGENASE MATURATION PROTEIN HYPF >gi|7449696|pir||D65051 hypF
           protein - Escherichia coli (strain K-12)
           >gi|2367152|gb|AAC75754.1| (AE000355) transcriptional
           regulatory protein [Escherichia coli K12]
           Length = 750
           
 Score =  428 bits (1090), Expect = e-119
 Identities = 285/767 (37%), Positives = 406/767 (52%), Gaps = 53/767 (6%)

Query: 5   RIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDLYRKK 64
           ++ ++G VQ VGFRPFV+++A   NL G V N GD GVE+ +    ED E FL  LY+  
Sbjct: 10  QLRIRGKVQGVGFRPFVWQLAQQLNLHGDVCNDGD-GVEVRLR---EDPETFLVQLYQHC 65

Query: 65  PPIAKIEKVEREEIPIQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDPTNKR 124
           PP+A+I+ VERE          +  + ST   G  ++ I PD A C  CL E+  P  +R
Sbjct: 66  PPLARIDSVEREPFIWSQLPTEFTIRQSTG--GTMNTQIVPDAATCPACLAEMNTPGERR 123

Query: 125 YMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPVACPV 184
           Y YPFI CT+CGPRFTII  +PYDR  T M  FP+C  C  EY DPL+RR+HA+PVACP 
Sbjct: 124 YRYPFINCTHCGPRFTIIRAMPYDRPFTVMAAFPLCPACDKEYRDPLDRRFHAQPVACPE 183

Query: 185 CGPSYRLYTSDGKEITGD-PLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVVAELRKR 243
           CGP    + S G+    +  L+ A   +  G I+AIKGIGG HLACDA   + VA LR R
Sbjct: 184 CGPHLE-WVSHGEHAEQEAALQAAIAQLKMGKIVAIKGIGGFHLACDARNSNAVATLRAR 242

Query: 244 LFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKREPFPLPENLAPGLHT 303
             RP KP A+M   L    G    +R   + LT+   PIV + K+    L +++AP L+ 
Sbjct: 243 KHRPAKPLAVM---LPVADGLPDAAR---QLLTTPAAPIVLVDKKYVPELCDDIAPDLNE 296

Query: 304 IGVMLPYAGTHYILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEKLKDVADYLLLHNRRI 363
           +GVMLP     ++L    + P+ VMTS N  G P    NE+A   L+ +AD  L+HNR I
Sbjct: 297 VGVMLPANPLQHLLLQELQCPL-VMTSGNLSGKPPAISNEQALADLQGIADGFLIHNRDI 355

Query: 364 PNRADDSVVRFVDGRRAVIRRSRGFVPLWIEIPFEYKG----LAVGAELMNAFGVAKNGK 419
             R DDSVVR       ++RRSRG+VP  + +P  +K     L +GA+L N F + +  +
Sbjct: 356 VQRMDDSVVR---ESGEMLRRSRGYVPDALALPPGFKNVPPVLCLGADLKNTFCLVRGEQ 412

Query: 420 VYPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPNYNTTKLAMEIAEEFN 479
              SQ++G+ S   +    REA++    I        VV D HP Y    ++ + A E N
Sbjct: 413 AVLSQHLGDLSDDGIQMQWREALRLMQNIYDFTP-QYVVHDAHPGY----VSSQWAREMN 467

Query: 480 AEFLQVQHHYAHVASVMAEHNLE----EVVGIALDGVGYGTDGKTWGGEIIYLSYEDIER 535
                V HH+AH A+ +AEH       +V+ + LDG+G G +G  WGGE + ++Y + E 
Sbjct: 468 LPTQTVLHHHAHAAACLAEHQWPLDGGDVIALTLDGIGMGENGALWGGECLRVNYRECEH 527

Query: 536 LAHLEYYPLPGGDLASYYPLRALIGILSLNHEIEEVENTIRKFCP---NAIKSLKYGETE 592
           L  L    LPGGDLA+  P R L+                 +F P   N  ++    +  
Sbjct: 528 LGGLPAVALPGGDLAAKQPWRNLLA-------------QCLRFVPEWQNYSETASVQQQN 574

Query: 593 LKVILRQLSSGINVAYASSTGRVLDAFSVLLNVS-YRRHYEGEPAMKLESFASQGKN-DL 650
             V+ R +  GIN   ASS GR  DA +  L  +     YEGE A  LE+ A+       
Sbjct: 575 WSVLARAIERGINAPLASSCGRFFDAVAAALGCAPATLSYEGEAACALEALAASCHGVTH 634

Query: 651 KLTIPVEGEEIRVSELFEEVLDLMGKASPRDIAYSIHLALARVFAEVSVEKAKEFGAKTV 710
            +T+P    ++ ++  +++ L+     + R  A++ H ALA+ FA +  E+A   G  T+
Sbjct: 635 PVTMPRVDNQLDLATFWQQWLNWQAPVNQR--AWAFHDALAQGFAALMREQATMRGITTL 692

Query: 711 VLGGGVGYNELIVKTVRKIVEGNGLKFLTTYEVPRGDNGINVGQAFL 757
           V  GGV +N L+   +   +    L F     +P GD G+++GQ  +
Sbjct: 693 VFSGGVIHNRLLRARLAHYLADFTLLF--PQSLPAGDGGLSLGQGVI 737


>gb|AAA69222.1| (U29579) CG Site No. 18232; alternate gene name hypF [Escherichia
           coli]
           Length = 750
           
 Score =  428 bits (1088), Expect = e-118
 Identities = 285/767 (37%), Positives = 405/767 (52%), Gaps = 53/767 (6%)

Query: 5   RIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDLYRKK 64
           ++ ++G VQ VGFRPFV+++A   NL G V N GD GVE+ +    ED E FL  LY+  
Sbjct: 10  QLRIRGKVQGVGFRPFVWQLAQQLNLHGDVCNDGD-GVEVRLR---EDPETFLVQLYQHC 65

Query: 65  PPIAKIEKVEREEIPIQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDPTNKR 124
           PP+A+I+ VERE          +  + ST   G  ++ I PD A C  CL E+  P  +R
Sbjct: 66  PPLARIDSVEREPFIWSQLPTEFTIRQSTG--GTMNTQIVPDAATCPACLAEMNTPGERR 123

Query: 125 YMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPVACPV 184
           Y YPFI CT+CGPRFTII  +PYDR  T M  FP+C  C  EY DPL+RR+HA+PVACP 
Sbjct: 124 YRYPFINCTHCGPRFTIIRAMPYDRPFTVMAAFPLCPACDKEYRDPLDRRFHAQPVACPE 183

Query: 185 CGPSYRLYTSDGKEITGD-PLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVVAELRKR 243
           CGP    + S G+    +  L+ A   +  G I+AIKGIGG HLACDA   + VA LR R
Sbjct: 184 CGPHLE-WVSHGEHAEQEAALQAAIAQLKMGKIVAIKGIGGFHLACDARNSNAVATLRAR 242

Query: 244 LFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKREPFPLPENLAPGLHT 303
             RP KP A+M   L    G    +R   + LT+   PIV + K+    L +++AP L+ 
Sbjct: 243 KHRPAKPLAVM---LPVADGLPDAAR---QLLTTPAAPIVLVDKKYVPELCDDIAPDLNE 296

Query: 304 IGVMLPYAGTHYILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEKLKDVADYLLLHNRRI 363
           +GVMLP     ++L    + P+ VMTS N  G P    NE+A   L+ +AD  L+HNR I
Sbjct: 297 VGVMLPANPLQHLLLQELQCPL-VMTSGNLSGKPPAISNEQALADLQGIADGFLIHNRDI 355

Query: 364 PNRADDSVVRFVDGRRAVIRRSRGFVPLWIEIPFEYKG----LAVGAELMNAFGVAKNGK 419
             R DDSVVR       ++RRSRG+VP  + +P  +K     L +GA+L N F + +  +
Sbjct: 356 VQRMDDSVVR---ESGEMLRRSRGYVPDALALPPGFKNVPPVLCLGADLKNTFCLVRGEQ 412

Query: 420 VYPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPNYNTTKLAMEIAEEFN 479
              SQ++G+ S   +    REA++    I        VV D HP Y    ++ + A E N
Sbjct: 413 AVLSQHLGDLSDDGIQMQWREALRLMQNIYDFTP-QYVVHDAHPGY----VSSQWAREMN 467

Query: 480 AEFLQVQHHYAHVASVMAEHNLE----EVVGIALDGVGYGTDGKTWGGEIIYLSYEDIER 535
                V HH+AH A+ +AEH       +V+ + LDG+G G +G  WGGE + ++Y + E 
Sbjct: 468 LPTQTVLHHHAHAAACLAEHQWPLDGGDVIALTLDGIGMGENGALWGGECLRVNYRECEH 527

Query: 536 LAHLEYYPLPGGDLASYYPLRALIGILSLNHEIEEVENTIRKFCP---NAIKSLKYGETE 592
           L  L    LPGGDLA+  P R L+                 +F P   N  ++       
Sbjct: 528 LGGLPAVALPGGDLAAKQPWRNLLA-------------QCLRFVPEWQNYSETASVQHQN 574

Query: 593 LKVILRQLSSGINVAYASSTGRVLDAFSVLLNVS-YRRHYEGEPAMKLESFASQGKN-DL 650
             V+ R +  GIN   ASS GR  DA +  L  +     YEGE A  LE+ A+       
Sbjct: 575 WSVLARAIERGINAPLASSCGRFFDAVAAALGCAPATLSYEGEAACALEALAASCHGVTH 634

Query: 651 KLTIPVEGEEIRVSELFEEVLDLMGKASPRDIAYSIHLALARVFAEVSVEKAKEFGAKTV 710
            +T+P    ++ ++  +++ L+     + R  A++ H ALA+ FA +  E+A   G  T+
Sbjct: 635 PVTMPRVDNQLDLATFWQQWLNWQAPVNQR--AWAFHDALAQGFAALMREQATMRGITTL 692

Query: 711 VLGGGVGYNELIVKTVRKIVEGNGLKFLTTYEVPRGDNGINVGQAFL 757
           V  GGV +N L+   +   +    L F     +P GD G+++GQ  +
Sbjct: 693 VFSGGVIHNRLLRARLAHYLADFTLLF--PQSLPAGDGGLSLGQGVI 737


>sp|Q02987|HYPF_RHOCA HYDROGENASE MATURATION PROTEIN HYPF >gi|479252|pir||S32948 hypF
           protein - Rhodobacter capsulatus
           >gi|46050|emb|CAA78795.1| (Z15087) hypF [Rhodobacter
           capsulatus]
           Length = 739
           
 Score =  418 bits (1064), Expect = e-116
 Identities = 287/779 (36%), Positives = 411/779 (51%), Gaps = 58/779 (7%)

Query: 1   MKAYRIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDL 60
           M+A+RI V+G VQ VGFRPFV+++A A  LRG V N  + GV I V G   D    LRD 
Sbjct: 1   MQAWRIRVRGQVQGVGFRPFVWQLARARGLRGVVLNDAE-GVLIRVAGDLGDFAAALRD- 58

Query: 61  YRKKPPIAKIEKVER-----EEIPIQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLR 115
             + PP+A+++ VE      +++P    + F I  S        ++ + PD A C DCL 
Sbjct: 59  --QAPPLARVDAVEVTAAVCDDLP----EGFQIAASGA---AGAETRVTPDAATCPDCLA 109

Query: 116 ELFDPTNKRYMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRY 175
           E+     +R  Y F  CT+CGPRF+I++ LPYDR  T M  F MC  C++EYEDP +RR+
Sbjct: 110 EIRGEGRRRG-YAFTNCTHCGPRFSILQSLPYDRARTTMAPFAMCPACRAEYEDPADRRF 168

Query: 176 HAEPVACPVCGPSYRLYTSDGKEITGDPLRKAAKLIDKGYIIAIKGIGGIHLACDATRED 235
           HA+P+ACP CGP   L  + G E+ GD +  AA  +  G I+A+KG+GG HLACDAT  D
Sbjct: 169 HAQPIACPDCGPRLWL-EAGGAELPGDAIGLAAARLKAGEILAVKGLGGFHLACDATNAD 227

Query: 236 VVAELRKRLFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKREPFPLPE 295
            V  LR R  RP KPFA+MA++ E +     +S      L     PIV +  R    LPE
Sbjct: 228 AVDLLRARKRRPAKPFALMARE-EDLARIVAVSPAALAALRDPAAPIVLMPARG--SLPE 284

Query: 296 NLAPGLHTIGVMLPYAGTHYILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEKLKDVADY 355
            LAPG+  +GVMLPY   H++L   +   V VMTS N  G P +  N+EA EKL   AD 
Sbjct: 285 TLAPGMAELGVMLPYTPLHHLLLD-AFGGVLVMTSGNLSGAPQVIGNDEAREKLSAFADA 343

Query: 356 LLLHNRRIPNRADDSVVRFVDGRRAVIRRSRGFVPLWIEIPFEYKG----LAVGAELMNA 411
            L+H+R I  R DDSVVR VD    V+RR+RG VP  + +P  ++     +A G ++  A
Sbjct: 344 FLMHDRAIARRLDDSVVR-VD-PPMVLRRARGQVPGTLPLPPGFETAPQIVAYGGQMKAA 401

Query: 412 FGVAKNGKVYPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPNYNTTKLA 471
             + K G+     ++G   +    E   +A   +  +   +    V  DLHP++  ++  
Sbjct: 402 LCLIKTGQALLGHHLGELDEALTWEAFLQADADYAALFD-HRPQAVAVDLHPDFRASRHG 460

Query: 472 MEIAEEFNAEFLQVQHHYAHVASVMAEH----NLEEVVGIALDGVGYGTDGKTWGGEIIY 527
              A       + VQHH+AH+A+ + E+    +  +V  I LDG+G G DG  WGGE++ 
Sbjct: 461 AARAGRLGVPLIAVQHHHAHLAACLGENLWPKDGGKVAVIVLDGLGLGPDGTVWGGELLL 520

Query: 528 LSYEDIERLAHLEYYPLPGGDLASYYPLR-ALIGILSLNHEIEEVENTIRKFCPNAIKSL 586
             Y+  ER+A L+  PL GGD A   P R AL+ +     +   + +   +  P A + L
Sbjct: 521 GDYKGFERVAWLKPAPLIGGDRAQIEPWRNALVRL-----DAAGLSDLADRLFPAAPRDL 575

Query: 587 KYGETELKVILRQLSS-GINVAYASSTGRVLDAFSVLLNV-SYRRHYEGEPAMKLESFAS 644
                      RQL++ GIN   +SS GR+ DA +  L +   R+ YEGE AM+LES A+
Sbjct: 576 ----------ARQLAAKGINAPLSSSAGRLFDAVAACLGICPMRQSYEGEAAMRLESLAA 625

Query: 645 QGKNDLKLTIPVEGEEIRVSELFEEVLDLMGKASPRDIAYSIHLALARVFAEVSVEKAKE 704
                    +P  G  I  + LF+    L     P  +A+++H +LA+ FA  +    + 
Sbjct: 626 D--TGPVPDLPCVGGAIDPAPLFQL---LAAGERPDRVAHALHASLAQAFAAEARRLIEA 680

Query: 705 FGAKTVVLGGGVGYNELIVKTVRKIVEGNGLKFLTTYEVPRGDNGINVGQAFLGGLYLE 763
             A+ V L GG   N  +    R  +   G+  LT   +P  D G+ +GQA +    LE
Sbjct: 681 GQAEAVALTGGCFQNSRLATMTRNFLADQGI--LTQGRIPANDGGLALGQALVAAAKLE 737


>dbj|BAA03315.1| (D14422) HYDA [Escherichia coli]
           Length = 749
           
 Score =  410 bits (1043), Expect = e-113
 Identities = 281/768 (36%), Positives = 398/768 (51%), Gaps = 56/768 (7%)

Query: 5   RIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDLYRKK 64
           ++ ++G VQ VGFRPFV+++A   NL G V N GD GVE+ +    ED E FL  LY+  
Sbjct: 10  QLRIRGKVQGVGFRPFVWQLARELNLHGDVCNDGD-GVEVRLR---EDPETFLVQLYQHC 65

Query: 65  PPIAKIEKVEREEIPIQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDPTNKR 124
           PP+A+I+ VERE          +  + ST   G  ++ I PD A C  CL E+  P  +R
Sbjct: 66  PPLARIDSVEREPFIWSQLPTEFTIRQSTG--GTMNTQIVPDAATCPACLAEMNTPGERR 123

Query: 125 YMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPVACPV 184
           Y YPFI CT+CGPRFTII  +PYDR  T M  FP+C  C  EY DPL+RR+HA+PVACP 
Sbjct: 124 YRYPFINCTHCGPRFTIIRAMPYDRPFTVMAAFPLCPACDKEYRDPLDRRFHAQPVACPE 183

Query: 185 CGPSYRLYTSDGKEITGD-PLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVVAELRKR 243
           CGP    + S G+    +  L+ A   +  G I+AIKGIGG HLACDA   + VA LR R
Sbjct: 184 CGPHLE-WVSHGEHAEQEAALQAAIAQLKMGKIVAIKGIGGFHLACDARNSNAVATLRAR 242

Query: 244 LFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKREPFPLPENLAPGLHT 303
             RP KP A+M   L    G    +R   + LT+   PIV + K+    L +++AP L+ 
Sbjct: 243 KHRPAKPLAVM---LPVADGLPDAAR---QLLTTPAAPIVLVDKKYVPELCDDIAPDLNE 296

Query: 304 IGVMLPYAGTHYILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEKLKDVADYLLLHNRRI 363
           +GVMLP     ++L    + P+ VMTS N  G P    NE+A   L+ +AD  L+HNR I
Sbjct: 297 VGVMLPANPLQHLLLQELQCPL-VMTSGNLSGKPPAISNEQALADLQGIADGFLIHNRDI 355

Query: 364 PNRADDSVVRFVDGRRA-----VIRRSRGFVPLWIEIPFEYKGLAVGAELMNAFGVAKNG 418
             R DDSVVR  + R A     V     GF   +  +P     L +GA+L N F + +  
Sbjct: 356 VQRMDDSVVR--ERRNAAPFAGVCAGCAGFASGFKNVP---PVLCLGADLKNTFCLVRGE 410

Query: 419 KVYPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPNYNTTKLAMEIAEEF 478
           +   SQ++G+ S   +     EA +    I        VV D HP Y    ++ + A E 
Sbjct: 411 QAVLSQHLGDLSDDGIQMQCAEASRLMQNIYDFTP-QYVVHDAHPGY----VSSQWAREM 465

Query: 479 NAEFLQVQHHYAHVASVMAEHNLE----EVVGIALDGVGYGTDGKTWGGEIIYLSYEDIE 534
           N     V HH+AH A+ +AEH       +V+ + LDG+G G +G  WGGE + ++Y + E
Sbjct: 466 NLPTQTVLHHHAHAAACLAEHQWPLDGGDVIALTLDGIGMGENGALWGGECLRVNYRECE 525

Query: 535 RLAHLEYYPLPGGDLASYYPLRALIGILSLNHEIEEVENTIRKFCP---NAIKSLKYGET 591
            L  L    LPGGDLA+  P R L+                 +F P   N  ++    + 
Sbjct: 526 HLGGLPAVALPGGDLAAKQPWRNLLA-------------QCLRFVPEWQNYSETASVQQQ 572

Query: 592 ELKVILRQLSSGINVAYASSTGRVLDAFSVLLNVS-YRRHYEGEPAMKLESFASQGKN-D 649
              V+ R +  GIN   ASS GR  DA +  L  +     YEGE A  LE+ A+      
Sbjct: 573 NWSVLARAIERGINAPLASSCGRFFDAVAAALGCAPATLSYEGEAACALEALAASCHGVT 632

Query: 650 LKLTIPVEGEEIRVSELFEEVLDLMGKASPRDIAYSIHLALARVFAEVSVEKAKEFGAKT 709
             +T+P    ++ ++  +++ L+     + R  A++ H ALA+ FA +  E+A   G  T
Sbjct: 633 HPVTMPRVDNQLDLATFWQQWLNWQAPVNQR--AWAFHDALAQGFAALMREQATMRGITT 690

Query: 710 VVLGGGVGYNELIVKTVRKIVEGNGLKFLTTYEVPRGDNGINVGQAFL 757
           +V  GGV +N L+   +   +    L F     +P GD G+++GQ  +
Sbjct: 691 LVFSGGVIHNRLLRARLAHYLADFTLLF--PQSLPAGDGGLSLGQGVI 736


>emb|CAB39912.1| (Y14197) uptake hydrogenase [Rhodobacter sphaeroides]
           Length = 758
           
 Score =  401 bits (1020), Expect = e-110
 Identities = 274/780 (35%), Positives = 404/780 (51%), Gaps = 70/780 (8%)

Query: 6   IHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDLYRKKP 65
           I V+G VQ VGFRPFV+++A    L G V N G AGV I   G    +  FL  L  + P
Sbjct: 9   IRVRGQVQGVGFRPFVWQLARRLGLEGEVLNDG-AGVMIRATGAR--LAEFLAALGTEAP 65

Query: 66  PIAKIEKVEREEIPIQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDPTNKRY 125
           P+A+++ VE    P+     F I  S+    G   + + PD A C  CL E+   T +R 
Sbjct: 66  PLARVDAVEARPAPVVRRP-FRIAASAG---GAVATRVTPDAATCPACLAEIRG-TGRRR 120

Query: 126 MYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPVACPVC 185
            Y F  CT+CGPR+TI+ +LPYDR  T+M  FPMC  C++EYEDP +RR+HA+P+ACP C
Sbjct: 121 GYAFTNCTHCGPRYTILRELPYDRARTSMAPFPMCPDCRAEYEDPADRRFHAQPIACPAC 180

Query: 186 GPSYRL-----------YTSDGKE------ITGDPLRKAAKLIDKGYIIAIKGIGGIHLA 228
           GP   L             ++G E        GDP+ +AA+L+ +G I+A+KG+GG HLA
Sbjct: 181 GPRLWLEAEGLCLLDGPVRAEGAEAPQGGLCAGDPVAEAARLLARGGILAVKGLGGFHLA 240

Query: 229 CDATREDVVAELRKRLFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKR 288
           CDA     + +LR R  RP KPFA+MA + E   G A +++ +   L     P+V +R R
Sbjct: 241 CDARDSGALRQLRLRKRRPGKPFALMATE-EMAAGIADLAQADRVLLRDPAAPVVLVRGR 299

Query: 289 EPFPLPENLAPGLHTIGVMLPYAGTHYILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEK 348
               LPE +APG+ T+G+M PY   H+ L      P+ VMTSAN  G P +  N EA  +
Sbjct: 300 G--LLPEEVAPGMTTLGIMRPYTPLHHRLIEAFGGPL-VMTSANRSGAPQVIGNGEARAE 356

Query: 349 LKDVADYLLLHNRRIPNRADDSVVRFVDGRRAVIRRSRGFVPLWIEIPFEY----KGLAV 404
           L  +AD  L+H+R I  R DDSV R       V+RR+RG  P  + +P  +    + LA+
Sbjct: 357 LAGIADAFLMHDRAIVRRLDDSVER--ARPPMVLRRARGRAPGTLPLPEGFGRAPRVLAL 414

Query: 405 GAELMNAFGVAKNGKVYPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPN 464
           G ++  A  + K+G+   S ++G+  + +  E    AI     +    A +LV  DLHP 
Sbjct: 415 GGQMKGAICLVKDGQALLSHHLGDLDEAQSFEAFTRAIADHAALFDHRA-ELVAVDLHPG 473

Query: 465 YNTTKLAMEIAEEFNAEFLQVQHHYAHVASVMAEH----NLEEVVGIALDGVGYGTDGKT 520
           Y  T    +          +VQHH+AH+A+ + +         V GI LDG G G+DG  
Sbjct: 474 YRAT----QEGRRMGLPLAEVQHHHAHLAACLGDAFWPLGAGPVAGIVLDGAGLGSDGTI 529

Query: 521 WGGEIIYLSYEDIERLAHLEYYPLPGGDLASYYPLR-ALIGILSLNHEIEEVENTIRKFC 579
           WGGE++  SY ++ R+AHL   PLPGG+ A+  P R AL+ +     +   + +   +  
Sbjct: 530 WGGELLLGSYREVLRVAHLAQAPLPGGEAAARDPWRNALVRL-----DAAGLGDLADRLF 584

Query: 580 PNAIKSLKYGETELKVILRQLSSGINVAYASSTGRVLDAFSVLLNVSY-RRHYEGEPAMK 638
           P+  +         + + R +++G+N   +SS GR+ DA +  L ++  R+ YEG+ AM+
Sbjct: 585 PDRPR---------ETLRRAVAAGVNAPLSSSAGRLFDAVAACLGLAADRQSYEGDAAMR 635

Query: 639 LESFASQGKNDLKLTIPVEGEEIRVSELFEEV-LDLMGKASPRDIAYSIHLALARVFAEV 697
           LE+    G        P     +  + +F  +  DL     P  I+ S+H  LAR     
Sbjct: 636 LEALEGTG-------APYPFAGLDPAPMFRALATDLAAGVPPGAISDSLHRGLARAVCAP 688

Query: 698 SVEKAKEFGAKTVVLGGGVGYNELIVKTVRKIVEGNGLKFLTTYEVPRGDNGINVGQAFL 757
           +        A+ V L GG   N  ++     + E  G+  LT   VP  D G+ +GQA +
Sbjct: 689 ARALVAGGRAEAVALTGGAFQNARLLAAC--LAELAGVPVLTHRAVPPNDGGLALGQALI 746


>pir||H64525 transcription regulator - Helicobacter pylori (strain 26695)
           >gi|2313122|gb|AAD07115.1| (AE000526) transcriptional
           regulator (hypF) [Helicobacter pylori 26695]
           Length = 769
           
 Score =  371 bits (942), Expect = e-101
 Identities = 251/769 (32%), Positives = 382/769 (49%), Gaps = 48/769 (6%)

Query: 5   RIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDLYRKK 64
           +I + G+VQ VG RPF+Y +A    L G+VRN   A +EI++   +   E FL  L +  
Sbjct: 22  KITLFGVVQGVGMRPFIYTLAQKLELVGFVRNT-QAALEIILPAHKT--ESFLNALKKGL 78

Query: 65  PPIAKIEKVEREEIP-IQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDPTNK 123
           PP+A +EK+          F+ F I +S         S IP D+ +C+DCLRE+ D  + 
Sbjct: 79  PPLALVEKIIISPYDKALHFNGFRILESKNHPLNLL-SQIPKDLGVCKDCLREIRDKNSP 137

Query: 124 RYMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPVACP 183
            + Y F  C  CG R++++  LPYDREN+A++ F +CDFC S Y+DP N+R+H + ++C 
Sbjct: 138 YFHYAFNSCAKCGARYSLLNALPYDRENSALKPFKLCDFCASIYQDPTNKRFHIQGISCK 197

Query: 184 VCG--PSYRLYTSDGKEITGDPLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVVAELR 241
            CG   +Y+ + +D      D L + AK I KG IIA+KG+GG  L CD      +  LR
Sbjct: 198 KCGIALNYKRFKND------DALLECAKDIQKGKIIALKGLGGFALLCDGRNFQTIERLR 251

Query: 242 KRLFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKREPFPLPENLAPGL 301
               RP KPFA+M KDL T K  A+++  E E L S   PI+  RK+    L  N+A   
Sbjct: 252 LLKNRPLKPFALMFKDLNTAKQHAFLNALECESLISTSAPILLARKKPDIKLAPNIAKNS 311

Query: 302 HTIGVMLPYAGTHYILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEKLKDVADYLLLHNR 361
              GV+LPY   H +L      P+ V TSANF  +P+  D  E  + L  + D+ L HNR
Sbjct: 312 PFYGVILPYTPLHALLLDLLDFPI-VFTSANFSSLPLASDEAE-IDALSFIFDFKLTHNR 369

Query: 362 RIPNRADDSVVRFVDGRRAVIRRSRGFVPLWIEIPFEYKG-----LAVGAELMNAFGVAK 416
            I +R DDS+V+ VD     +R +RGF PL++ +P    G     LA+GA+    F +  
Sbjct: 370 AIIHRIDDSIVQHVDNAIRPMRLARGFAPLYLTLPKRSNGSPKKILALGAQQKGHFSLLD 429

Query: 417 NGK--VYPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPNYNTTKLAMEI 474
           +G   +  S + G+ S +E  +  +E +  F K        ++  D H NY TT++A   
Sbjct: 430 SGTSILLLSPFCGDLSVLENEKHFKETLNFFLKTYDFKP-TILACDKHQNYTTTQMAF-- 486

Query: 475 AEEFNAEFLQVQHHYAH-VASVM-----AEHNLEEVVGIALDGVGYGTDGKTWGGEIIYL 528
             +FN   LQVQHH+AH +ASV+       H     +GI  DG G   + K +G E    
Sbjct: 487 --DFNTPLLQVQHHHAHFLASVLDALLQDPHLNHPFIGIVWDGSG-AYENKIYGAECFVG 543

Query: 529 SYEDIERLAHLEYYPLPGGDLASYYPLRALIGILSLNHEIEEVENTIRKFCPNAIKSLKY 588
             E IE  A  E + L GG  A   P R ++ I +L H++ ++   ++K          +
Sbjct: 544 DLERIEETARFEEFWLLGGQKAIKEPRRLVLEI-ALKHQLNKLLKRVQK---------HF 593

Query: 589 GETELKVILRQLSSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLESFASQGKN 648
            E EL++  +     I     +S GR+ D  +  L+++    +E E    LE+ A Q   
Sbjct: 594 KEDELEIFQQMHDKKIQSIATNSIGRLFDIVAFSLDLTGTISFEAESGQVLENLALQSDE 653

Query: 649 DLKLTIPVEGEEIRVSELFEEVLDLMGKASPRDIAYSIHLALARVFAEVSVEKAKEFGAK 708
                  ++   + + E ++     +G   P  IA     +L  +   + V     F   
Sbjct: 654 IAFYPFEIKNSVVCLKEFYQAFEKDLGVLEPERIAKKFFNSLVEIITALIV----PFKEH 709

Query: 709 TVVLGGGVGYNELIVKTVRKIVEGNGLKFLTTYEVPRGDNGINVGQAFL 757
            VV  GGV  N+L+ + + K + G   ++      P  D+ I +GQA +
Sbjct: 710 VVVCSGGVFCNQLLCEQLAKRLRGLKRQYFFHKHFPPNDSSIPIGQALM 758


>pir||G71981 probable transcription regulator - Helicobacter pylori  (strain
           J99) >gi|4154540|gb|AAD05618.1| (AE001443) putative
           TRANSCRIPTIONAL REGULATOR [Helicobacter pylori J99]
           Length = 757
           
 Score =  360 bits (914), Expect = 4e-98
 Identities = 253/773 (32%), Positives = 381/773 (48%), Gaps = 56/773 (7%)

Query: 5   RIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDLYRKK 64
           +I + G+VQ VG RPFVY +A    L G+VRN   A +EIV+   +   E FL  L +  
Sbjct: 10  KITLFGVVQGVGMRPFVYILAQKLGLVGFVRN-AQAALEIVLPAHKT--ESFLNALKKGL 66

Query: 65  PPIAKIEKVEREEIPIQGFDR--FYIEKSSTEKKGEGDSI---IPPDIAICEDCLRELFD 119
           PP+A +EK     I I  +D+   + +    E K    ++   IP D+ +CEDCL E+ D
Sbjct: 67  PPLALVEK-----IIISPYDKALHFNDFRILESKNHPLNLLSQIPKDLGVCEDCLCEIRD 121

Query: 120 PTNKRYMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEP 179
             +  + Y F  C  CG R++++  +PYDREN+A++ F +C FC S Y+D  N+R+H + 
Sbjct: 122 KNSPYFHYAFNSCAKCGARYSLLNAMPYDRENSALKPFKLCKFCASVYKDAHNKRFHIQG 181

Query: 180 VACPVCG--PSYRLYTSDGKEITGDPLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVV 237
           ++C  CG   +Y+ + +D      D L + AK I KG IIA+KG+GG  L CDA     +
Sbjct: 182 ISCKKCGIALNYKRFKND------DALLECAKDIQKGKIIALKGLGGFALLCDARNFKTI 235

Query: 238 AELRKRLFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKREPFPLPENL 297
             LR    RP KPFA+M KDL   K  A+++  E E L S   PI+  RK+    L  N+
Sbjct: 236 ERLRLLKNRPLKPFALMFKDLNAAKQHAFLNALECESLNSVSAPILLARKKPDTQLAPNI 295

Query: 298 APGLHTIGVMLPYAGTHYILFHWSKTPVYVMTSANFPGMPMIKDNEEAFEKLKDVADYLL 357
           A      GV+LPY   H +L     +P+ V TSANF  +P+  D +E  + L  + D+ L
Sbjct: 296 AKNSPFYGVILPYTPLHALLLDLLDSPI-VFTSANFSSLPLASDEKE-IDSLHFIFDFKL 353

Query: 358 LHNRRIPNRADDSVVRFVDGRRAVIRRSRGFVPLWIEIP-----FEYKGLAVGAELMNAF 412
            HNR I +R DDS+ + VD     +R  RGF PL++ +P        K LA+GAE    F
Sbjct: 354 THNRTIIHRIDDSIAQRVDNAIRPMRLVRGFAPLYLTLPKRSFNAPKKILALGAEQKGHF 413

Query: 413 GV--AKNGKVYPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPNYNTTKL 470
            +  ++   +  S + G+ S +E  +  +E +  F K        L+  D H NY TTK+
Sbjct: 414 SLLDSETSVLLLSPFCGDLSVLENEKHFKETLNFFLKTYDFKP-TLLACDEHQNYTTTKM 472

Query: 471 AMEIAEEFNAEFLQVQHHYAH-VASVM-----AEHNLEEVVGIALDGVGYGTDGKTWGGE 524
           A     +FN   LQVQHH+AH +ASV+       H     +GI  DG G   + K +G E
Sbjct: 473 AF----DFNTPLLQVQHHHAHFLASVLDALLQDPHLNHPFIGIVWDGSG-AYENKIYGAE 527

Query: 525 IIYLSYEDIERLAHLEYYPLPGGDLASYYPLRALIGILSLNHEIEEVENTIRKFCPNAIK 584
                 E IE +A  E + L GG  A   P R ++ I +L H++ ++   ++K       
Sbjct: 528 CFVGDLERIEEVARFEEFWLLGGQKAIKEPRRLVLEI-ALKHQLNKLLKRVQK------- 579

Query: 585 SLKYGETELKVILRQLSSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLESFAS 644
              + E EL +  +     I     +S GR+ D  +  L V     +E E    LE+ A 
Sbjct: 580 --HFKEDELGIFKQMHDKKIQSVATNSIGRLFDIVAFSLGVVGTISFEAESGQVLENLAL 637

Query: 645 QGKNDLKLTIPVEGEEIRVSELFEEVLDLMGKASPRDIAYSIHLALARVFAEVSVEKAKE 704
           Q          ++   +R+ E ++     +G   P+ IA     +L     E+       
Sbjct: 638 QSDEIAFYPFEIKNSVVRLKEFYQAFEKDLGVLEPKRIAKKFFNSL----VEIITALIAP 693

Query: 705 FGAKTVVLGGGVGYNELIVKTVRKIVEGNGLKFLTTYEVPRGDNGINVGQAFL 757
           F    VV  GGV  N+L+ + + K ++    ++      P  D+ I VGQA +
Sbjct: 694 FKGHVVVCSGGVFCNQLLCEQLAKRLKKLQREYFFHKHFPPNDSSIPVGQALM 746


>emb|CAA85443.1| (Z36981) HYPF [Rhizobium leguminosarum]
           Length = 476
           
 Score =  343 bits (870), Expect = 5e-93
 Identities = 194/478 (40%), Positives = 278/478 (57%), Gaps = 26/478 (5%)

Query: 1   MKAYRIHVQGIVQAVGFRPFVYRIAHAHNLRGYVRNLGDAGVEIVVEGREEDIEGFLRDL 60
           ++  R+ V+G VQ VGFRPF YR+A A  L G+V N   AGV I +EGR  D   F   +
Sbjct: 13  VRRLRLRVRGAVQGVGFRPFAYRLARAMRLSGFVLN-DSAGVLIEIEGR--DANHFPEAV 69

Query: 61  YRKKPPIAKIEKVEREEIPIQGFDRFYIEKSSTEKKGEGDSIIPPDIAICEDCLRELFDP 120
             + PP+A+I+ ++  E+   G +RF I +S     G   + I  D A C+ C REL DP
Sbjct: 70  RTQAPPLARIDSIDVLELVPAGGERFEILESLG---GRSATRIGADAATCDGCRRELTDP 126

Query: 121 TNKRYMYPFIVCTNCGPRFTIIEDLPYDRENTAMREFPMCDFCKSEYEDPLNRRYHAEPV 180
            ++ + YPF+ CT+CGPRFTI   LPYDR +T+M  FPMC  C ++Y DP NRR+HAEPV
Sbjct: 127 ASRFFGYPFVNCTHCGPRFTITRALPYDRAHTSMASFPMCRTCAADYVDPENRRFHAEPV 186

Query: 181 ACPVCGPSYRLYTSDGKEITGDPLRKAAKLIDKGYIIAIKGIGGIHLACDATREDVVAEL 240
           ACP CGP               P+++ +  ++ G I+A+KG+GG HL CDA  +  +  L
Sbjct: 187 ACPNCGPR-----------LSHPIKEISARLEGGAIVALKGVGGFHLLCDARNDGAIGLL 235

Query: 241 RKRLFRPQKPFAIMAKDLETVKGFAYISREEEEELTSYRRPIVALRKREPFPLPENLAPG 300
           R R  R QKPFA+M +D+E  +  A  +  EE  L S  RPIV +  R    L   +APG
Sbjct: 236 RLRKARDQKPFAVMVRDIEAARQLARPNEAEEALLISPARPIVLVAARAG-ELSGLIAPG 294

Query: 301 LHTIGVMLPYAGTHYILF-HWSKTPVY-----VMTSANFPGMPMIKDNEEAFEKLKDVAD 354
           L  +G+ML YA  H++L    S++  +     V TSAN  G P++ DN++A  +L  +AD
Sbjct: 295 LTRVGLMLAYAPVHHLLLDELSRSSPHCHAALVATSANPGGEPLVADNDDAGRRLVAIAD 354

Query: 355 YLLLHNRRIPNRADDSVVRFVDGRRAVIRRSRGFVPLWIEIPFEYKG-LAVGAELMNAFG 413
            ++ H+R I  RADDSV++ +DG  A IRR+RGFVP  +++  +    +A GA+L N   
Sbjct: 355 LVVTHDRDIVVRADDSVMQVIDGAPAFIRRARGFVPEPVDLGADGPSVIATGADLKNTIC 414

Query: 414 VAKNGKVYPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADLHPNYNTTKLA 471
           V +  + + SQ+IG     E + F RE I H   IL +   +    DLHP++ + + A
Sbjct: 415 VTRGREAFLSQHIGGLDNAEAIRFQREVIAHLCSILDVKP-EFAACDLHPDFRSVRTA 471


>sp|P45805|HYF1_ALCEU HYDROGENASE MATURATION PROTEIN HYPF1 >gi|2120944|pir||I39530 hypF
           protein - Alcaligenes eutrophus >gi|7465681|pir||S29976
           hypF1 protein - Alcaligenes eutrophus
           >gi|577728|emb|CAA49731.1| (X70183) HYPF [Ralstonia
           eutropha]
           Length = 394
           
 Score =  163 bits (409), Expect = 6e-39
 Identities = 115/366 (31%), Positives = 184/366 (49%), Gaps = 20/366 (5%)

Query: 402 LAVGAELMNAFGVAKNGKVYPSQYIGNTSKIEVLEFMREAIKHFFKILRINALDLVVADL 461
           LA GA L NA  + +  +V  S   G+       + + ++++          +  V  DL
Sbjct: 16  LACGAWLKNAACLLRGAEVLWSPIHGDLGDPANCDALDQSVEQLLDSAH-GQVQAVAHDL 74

Query: 462 HPNYNTTKLAMEIAEEFNAEFLQVQHHYAHVASVMAEHNLEE-VVGIALDGVGYGTDGKT 520
           HP++ +T+LA  +A       + VQHH+AH+A++MAE++L E V+G+ALDGVG GTDG  
Sbjct: 75  HPDFYSTQLAQRLAARLCVPAVAVQHHHAHIAALMAEYDLREPVIGLALDGVGLGTDGTA 134

Query: 521 WGGEIIYLSYEDIERLAHLEYYPLPGGDLASYYPLRALIGILSLNHEIEEVENTIRKFCP 580
           WGGE++++S  +  RL HL+  PLPGGD+A+  P R     L   H ++      R++  
Sbjct: 135 WGGELLWVSPSEWCRLGHLQSLPLPGGDVAAREPWRMAAAAL---HVLDRTGEIGRRY-- 189

Query: 581 NAIKSLKYGETELKVILRQLSSGINVAYASSTGRVLDAFSVLLNVSYRRHYEGEPAMKLE 640
                   GE   + +   L   +N   +SS GR  DA +  L VS R+  E + A+ LE
Sbjct: 190 ----GAVVGEQAARTVAAMLERQLNCPRSSSAGRWFDAAAGALGVSVRQQAEAQAAIALE 245

Query: 641 SFASQGKNDLKL-----TIPVEGEEI-RVSELFEEVLDLMGKASPRDIAYS---IHLALA 691
           + A+   + L       T  V+ + +  +  L E++  L  +      A      H+ALA
Sbjct: 246 ALAADYLSALSPPECVGTYVVDQDGVLDLRGLLEQLFALADEGQAGQAARGAALFHVALA 305

Query: 692 RVFAEVSVEKAKEFGAKTVVLGGGVGYNELIVKTVRKIVEGNGLKFLTTYEVPRGDNGIN 751
                 + + A+  G KTV LGGG   N ++  +V+  +   GL+ L    V  GD G+ 
Sbjct: 306 EALVGWAADAAQGHGLKTVALGGGCFMNGILSASVQAGLAARGLQALLPRAVSCGDAGLA 365

Query: 752 VGQAFL 757
           +GQA++
Sbjct: 366 LGQAWV 371


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.321    0.141    0.414 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 293682594
Number of Sequences: 2977
Number of extensions: 13108552
Number of successful extensions: 31771
Number of sequences better than 1.0e-10: 24
Number of HSP's better than  0.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 31502
Number of HSP's gapped (non-prelim): 25
length of query: 773
length of database: 189,106,746
effective HSP length: 56
effective length of query: 717
effective length of database: 155,591,474
effective search space: 111559086858
effective search space used: 111559086858
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 169 (70.2 bits)