BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1561 (PAB1561) DE:DNA helicase, putative
         (653 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||B75105 probable DNA helicas PAB1561 - Pyrococcus abyssi (st...  1279  0.0
pir||E71080 probable DNA-binding protein - Pyrococcus horikoshii...  1116  0.0
pir||G72429 hypothetical protein TM0005 - Thermotoga maritima (s...   792  0.0
gi|11498984 DNA helicase, putative [Archaeoglobus fulgidus] >gi|...   737  0.0
pir||D69085 transcription control factor enhancer-binding protei...   687  0.0
sp|Q57568|Y104_METJA HYPOTHETICAL ATP-BINDING PROTEIN MJ0104 >gi...   540  e-152
pir||D70476 DNA helicase - Aquifex aeolicus >gi|2984278|gb|AAC07...   461  e-129
pir||T02699 hypothetical protein T18E12.6 - Arabidopsis thaliana...   352  6e-96
emb|CAC16347.1| (AJ300306) putative helicase [Arabidopsis thaliana]   351  1e-95
gb|AAG28561.1|AF199411_1 (AF199411) antifreeze-enhancer binding ...   300  3e-80
gi|4504623 immunoglobulin mu binding protein 2 [Homo sapiens] >g...   299  7e-80
pir||A47500 Ig mu chain switch region binding protein 2 - human       299  7e-80
gi|11435569 immunoglobulin mu binding protein 2 [Homo sapiens]        298  2e-79
sp|Q60560|SMB2_MESAU DNA-BINDING PROTEIN SMUBP-2 (IMMUNOGLOBULIN...   296  5e-79
gb|AAA70430.1| (L24544) DNA helicase [Homo sapiens]                   295  8e-79
gi|6678029 immunoglobulin S mu binding protein 2 [Mus musculus] ...   294  1e-78
pir||T41580 probable dna-binding protein - fission yeast  (Schiz...   262  1e-68
gi|6322835 DNA helicase A; Hcs1p [Saccharomyces cerevisiae] >gi|...   230  3e-59
dbj|BAB09253.1| (AB026643) DNA helicase-like [Arabidopsis thaliana]   219  6e-56
pir||D72258 helicase-related protein - Thermotoga maritima (stra...   215  9e-55
emb|CAC18314.1| (AL451022) probable HUPF1 protein [Neurospora cr...   215  2e-54
pir||T43280 nonsense-mediated mRNA decay trans-acting factor - C...   206  6e-52
gi|6323726 putative helicase; Nam7p [Saccharomyces cerevisiae] >...   202  1e-50
dbj|BAB10240.1| (AB013394) prematurely terminated mRNA decay fac...   200  3e-50
pir||T40065 tRNA-splicing endonuclease positive effector - fissi...   197  3e-49
gb|AAB94785.1| (AC003972) pNORF1 [Homo sapiens] >gi|3328175|gb|A...   192  7e-48
gb|AAC51140.1| (U59323) type 1 RNA helicase pNORF1 [Homo sapiens]     192  7e-48
dbj|BAA19664.1| (D86988) KIAA0221 [Homo sapiens]                      192  7e-48
sp|Q09820|YAC6_SCHPO HYPOTHETICAL 105.6 KD PROTEIN C16C9.06C IN ...   191  2e-47
pir||T37779 probable regulator of nonsense transcript stability ...   191  2e-47
gi|11426635 regulator of nonsense transcripts 1 [Homo sapiens]        190  4e-47
gi|4506479 regulator of nonsense transcripts 1 [Homo sapiens] >g...   190  5e-47
sp|Q92355|YDHA_SCHPO HYPOTHETICAL 192.5 KD PROTEIN C6G9.10C IN C...   184  3e-45
emb|CAC10094.1| (AL442164) related to SEN1 protein [Neurospora c...   174  2e-42
gb|AAB63976.1| (M74589) SEN1 [Saccharomyces cerevisiae]               167  3e-40
gi|6323462 component of a nuclear-localized tRNA splicing comple...   167  3e-40
gb|AAG19799.1| (AE005064) DNA helicase; Hel [Halobacterium sp. N...   167  4e-40
gi|6321024 DNA Helicase I; Ecm32p [Saccharomyces cerevisiae] >gi...   161  3e-38
pir||T39568 hypothetical helicase - fission yeast (Schizosacchar...   159  1e-37
pir||T51292 Dna2p - fission yeast (Schizosaccharomyces pombe) >g...   159  1e-37
gb|AAF99770.1|AC003981_20 (AC003981) F22O13.33 [Arabidopsis thal...   158  2e-37
sp|P51530|Y083_HUMAN HYPOTHETICAL PROTEIN KIAA0083 >gi|11360302|...   158  2e-37
pir||T08986 hypothetical protein F6G3.130 - Arabidopsis thaliana...   157  5e-37
pir||T26415 hypothetical protein Y106G6D.5 - Caenorhabditis eleg...   153  5e-36
pir||T00533 SEN1 protein homolog T20K24.14 - Arabidopsis thalian...   152  2e-35
dbj|BAA31600.1| (AB014525) KIAA0625 protein [Homo sapiens]            148  2e-34
gi|7662212 KIAA0625 protein [Homo sapiens] >gi|7022724|dbj|BAA91...   148  2e-34
gi|11429653 KIAA0625 protein [Homo sapiens]                           148  2e-34
gb|AAG20303.1| (AE005104) DNA binding protein eukaryotic-like; D...   147  4e-34
gb|AAF23837.1|AC007234_9 (AC007234) F1E22.14 [Arabidopsis thaliana]   142  1e-32
gb|AAG09081.1|AC026237_2 (AC026237) Similar to tRNA-splicing end...   138  1e-31
gb|AAF50482.1| (AE003556) CG7504 gene product [Drosophila melano...   137  3e-31
pir||T28788 hypothetical protein C41D11.7 - Caenorhabditis elega...   136  1e-30
dbj|BAB11057.1| (AB015478) contains similarity to nonsense-media...   135  1e-30
gb|AAF57908.1| (AE003804) CG6967 gene product [Drosophila melano...   134  2e-30
gi|6321958 DNA replication helicase; Dna2p [Saccharomyces cerevi...   134  3e-30
dbj|BAB11372.1| (AB017068) contains similarity to nonsense-media...   131  2e-29
gb|AAB67523.1| (U21094) Sen1p [Saccharomyces cerevisiae]              131  3e-29
pir||T22132 hypothetical protein F43G6.1a - Caenorhabditis elega...   131  3e-29
pir||T22138 hypothetical protein F43G6.1b - Caenorhabditis elega...   131  3e-29
gi|11499542 DNA helicase, putative [Archaeoglobus fulgidus] >gi|...   130  4e-29
dbj|BAB11370.1| (AB017068) contains similarity to nonsense-media...   127  4e-28
pir||T00740 hypothetical protein F22O13.35 - Arabidopsis thaliana     125  1e-27
dbj|BAB08973.1| (AB024026) gb|AAD48967.1~gene_id:K15O15.6~strong...   122  1e-26
dbj|BAB11373.1| (AB017068) contains similarity to DNA helicase~g...   122  1e-26
gb|AAD48967.1|AF147263_9 (AF147263) contains similarity to nonse...   122  2e-26
gb|AAF23836.1|AC007234_8 (AC007234) F1E22.16 [Arabidopsis thaliana]   122  2e-26
gb|AAF46543.1| (AE003449) CG2990 gene product [Drosophila melano...   120  4e-26
gb|AAF56255.1| (AE003746) CG6204 gene product [Drosophila melano...   115  2e-24
gb|AAA58611.1| (M64979) glial factor-1 [Homo sapiens]                 115  2e-24
pir||A70369 hypothetical protein aq_791 - Aquifex aeolicus >gi|2...   112  1e-23
pir||D64588 probable DNA helicase - Helicobacter pylori (strain ...   109  9e-23
pir||T41111 hypothetical ATP binding protein - fission yeast  (S...   101  2e-20
gb|AAF79736.1|AC005106_17 (AC005106) T25N20.11 [Arabidopsis thal...    99  1e-19
gb|AAF58307.1| (AE003816) CG6701 gene product [Drosophila melano...    96  9e-19
dbj|BAA92642.1| (AB037825) KIAA1404 protein [Homo sapiens]             95  2e-18
dbj|BAB14696.1| (AK023836) unnamed protein product [Homo sapiens]      95  2e-18
pir||T42668 hypothetical protein DKFZp434B0717.1 - human (fragme...    95  3e-18
pir||T47242 DNA helicase homolog - fission yeast (Schizosaccharo...    93  8e-18
gb|AAF47775.1| (AE003478) CG11513 gene product [Drosophila melan...    92  2e-17
gi|6678920 Moloney leukemia virus 10 [Mus musculus] >gi|127560|s...    92  2e-17
dbj|BAB13457.1| (AB046851) KIAA1631 protein [Homo sapiens]             90  5e-17
emb|CAB63041.1| (AL022328) dJ402G11.8 (novel protein similar to ...    90  7e-17
dbj|BAA90895.1| (AK000033) unnamed protein product [Homo sapiens]      88  3e-16
emb|CAC15527.1| (AL121829) dJ697K14.7 (putative novel protein) [...    85  2e-15
pir||G64575 conserved hypothetical protein HP0447 - Helicobacter...    84  4e-15
pir||B75198 DNA helicase related protein PAB0067 - Pyrococcus ab...    83  9e-15
emb|CAB60444.1| (AL132853) cDNA EST yk10h1.5 comes from this gen...    83  1e-14
pir||T46441 hypothetical protein DKFZp434C0927.1 - human >gi|680...    83  1e-14
pir||T27684 hypothetical protein ZK1067.2 - Caenorhabditis elega...    82  3e-14
pir||T23039 hypothetical protein H03G16.3 - Caenorhabditis elega...    81  3e-14
gb|AAF54715.1| (AE003693) CG14730 gene product [Drosophila melan...    81  4e-14
emb|CAB65628.1| (AL049766) dJ686N3.2 (novel protein similar to p...    78  2e-13
pir||T29386 hypothetical protein K08D10.5 - Caenorhabditis elega...    77  7e-13
sp|Q09449|YQ12_CAEEL HYPOTHETICAL 175.7 KD PROTEIN C05C10.2 IN C...    73  1e-11
pir||T23869 hypothetical protein R03D7.2 - Caenorhabditis elegan...    72  2e-11
pir||S75309 hypothetical protein sll1582 - Synechocystis sp. (st...    72  2e-11
dbj|BAB14299.1| (AK022902) unnamed protein product [Homo sapiens]      72  2e-11

>pir||B75105 probable DNA helicas PAB1561 - Pyrococcus abyssi (strain Orsay)
           >gi|5458655|emb|CAB50143.1| (AJ248286) DNA helicase,
           putative [Pyrococcus abyssi]
           Length = 653
           
 Score = 1279 bits (3274), Expect = 0.0
 Identities = 653/653 (100%), Positives = 653/653 (100%)

Query: 1   MNITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYFL 60
           MNITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYFL
Sbjct: 1   MNITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYFL 60

Query: 61  VKYGRNREIKTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWALRDVRI 120
           VKYGRNREIKTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWALRDVRI
Sbjct: 61  VKYGRNREIKTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWALRDVRI 120

Query: 121 DLYANDITFRRWLENLNTIKKAGKRALRFYLGLDEPSQGEEVNFVPFDKSLNRSQRKAIS 180
           DLYANDITFRRWLENLNTIKKAGKRALRFYLGLDEPSQGEEVNFVPFDKSLNRSQRKAIS
Sbjct: 121 DLYANDITFRRWLENLNTIKKAGKRALRFYLGLDEPSQGEEVNFVPFDKSLNRSQRKAIS 180

Query: 181 KALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLSRSGIK 240
           KALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLSRSGIK
Sbjct: 181 KALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLSRSGIK 240

Query: 241 IVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGL 300
           IVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGL
Sbjct: 241 IVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGL 300

Query: 301 SDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREADV 360
           SDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREADV
Sbjct: 301 SDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREADV 360

Query: 361 VLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSL 420
           VLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSL
Sbjct: 361 VLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSL 420

Query: 421 EAQELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRD 480
           EAQELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRD
Sbjct: 421 EAQELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRD 480

Query: 481 LVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLL 540
           LVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLL
Sbjct: 481 LVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLL 540

Query: 541 SIGVKPEWIGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIG 600
           SIGVKPEWIGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIG
Sbjct: 541 SIGVKPEWIGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIG 600

Query: 601 FLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGCFIEFPFS 653
           FLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGCFIEFPFS
Sbjct: 601 FLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGCFIEFPFS 653


>pir||E71080 probable DNA-binding protein - Pyrococcus horikoshii
           >gi|3257320|dbj|BAA30003.1| (AP000004) 656aa long
           hypothetical DNA-binding protein [Pyrococcus horikoshii]
           Length = 656
           
 Score = 1116 bits (2855), Expect = 0.0
 Identities = 563/648 (86%), Positives = 605/648 (92%)

Query: 1   MNITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYFL 60
           MNI SFINRLKELVEIE+EAEIEAMRLEM+RLSG+ERERLGRAILNLNGKI GEELGYFL
Sbjct: 1   MNIKSFINRLKELVEIEKEAEIEAMRLEMKRLSGVERERLGRAILNLNGKIAGEELGYFL 60

Query: 61  VKYGRNREIKTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWALRDVRI 120
           VKYGRNREIKTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWALRDVRI
Sbjct: 61  VKYGRNREIKTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWALRDVRI 120

Query: 121 DLYANDITFRRWLENLNTIKKAGKRALRFYLGLDEPSQGEEVNFVPFDKSLNRSQRKAIS 180
           DLYANDITFRRWLENL+ +KKAGKRAL FYLGLDEPSQGEEV+F PFDKSLN SQRKAI+
Sbjct: 121 DLYANDITFRRWLENLDRVKKAGKRALEFYLGLDEPSQGEEVSFEPFDKSLNSSQRKAIA 180

Query: 181 KALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLSRSGIK 240
           K LGSEDFFL+HGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERL++ G+K
Sbjct: 181 KGLGSEDFFLIHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLAKDGVK 240

Query: 241 IVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGL 300
           IVR+GHPSRVS+HLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGL
Sbjct: 241 IVRVGHPSRVSRHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGL 300

Query: 301 SDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREADV 360
           SD EIIKLAER+RG RGLSARLI EMAEWIKLNRQVQKAF+DARKLEERIARDIIREADV
Sbjct: 301 SDAEIIKLAERRRGIRGLSARLIKEMAEWIKLNRQVQKAFEDARKLEERIARDIIREADV 360

Query: 361 VLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSL 420
           +LTTNSSAALEVVD   YDVAIIDEATQ+TIPSILIPLNKV+RF+LAGDHKQLPPTILSL
Sbjct: 361 ILTTNSSAALEVVDATDYDVAIIDEATQATIPSILIPLNKVDRFILAGDHKQLPPTILSL 420

Query: 421 EAQELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRD 480
           EAQELS TLFEGLIERYPWKSEML +QYRMNERIMEFPSKEFY G+I+ADE V+ ITL D
Sbjct: 421 EAQELSHTLFEGLIERYPWKSEMLTIQYRMNERIMEFPSKEFYDGRIVADERVKNITLGD 480

Query: 481 LVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLL 540
           L    +    W  IL+P NV+VFIDT   +N++ERQRRGSESRENPLEA+IV+KIV+KLL
Sbjct: 481 LGIKVNATGIWRDILDPSNVLVFIDTCMLDNRFERQRRGSESRENPLEAKIVSKIVEKLL 540

Query: 541 SIGVKPEWIGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIG 600
             GVK E IGVITPYDDQRDLIS+ VPE+VEVKTVDGYQGREKEVIILS VRSNK+GEIG
Sbjct: 541 ESGVKAEMIGVITPYDDQRDLISLNVPEEVEVKTVDGYQGREKEVIILSFVRSNKVGEIG 600

Query: 601 FLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGCFI 648
           FLKDLRRLNVSLTRAKRKLI++GDSSTLSSHETYK++IE  +EKG ++
Sbjct: 601 FLKDLRRLNVSLTRAKRKLIMIGDSSTLSSHETYKRLIEHVREKGLYV 648


>pir||G72429 hypothetical protein TM0005 - Thermotoga maritima (strain MSB8)
           >gi|4980488|gb|AAD35099.1|AE001689_5 (AE001689) DNA
           helicase, putative [Thermotoga maritima]
           Length = 650
           
 Score =  792 bits (2022), Expect = 0.0
 Identities = 405/651 (62%), Positives = 508/651 (77%), Gaps = 2/651 (0%)

Query: 1   MNITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYFL 60
           M +  FI +L  LVE+ER AEI AM  EM+RLSG ERE+ GRA+L L GK IGEELGYFL
Sbjct: 1   MTVQQFIKKLVRLVELERNAEINAMLDEMKRLSGEEREKKGRAVLGLTGKFIGEELGYFL 60

Query: 61  VKYGRNREIKTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWALRDVRI 120
           V++GR ++I TEI VGDLV+ISK +PLKSD  GTVVEKG+RFI VA++ +P W L++VRI
Sbjct: 61  VRFGRRKKIDTEIGVGDLVLISKGNPLKSDYTGTVVEKGERFITVAVDRLPSWKLKNVRI 120

Query: 121 DLYANDITFRRWLENLNTIKKAGKRALRFYLGLDEPSQGEEVNFVPFDKSLNRSQRKAIS 180
           DL+A+DITFRR +ENL T+   GK+AL F LG  +P +  E  F PFD+ LN SQR+A+S
Sbjct: 121 DLFASDITFRRQIENLMTLSSEGKKALEFLLGKRKPEESFEEEFTPFDEGLNESQREAVS 180

Query: 181 KALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLSRSGIK 240
            ALGS DFFL+HGPFGTGKTRTLVE IRQEV RG K+L TAESN+AVDNLVERL    + 
Sbjct: 181 LALGSSDFFLIHGPFGTGKTRTLVEYIRQEVARGKKILVTAESNLAVDNLVERL-WGKVS 239

Query: 241 IVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGL 300
           +VRIGHPSRVS HL E+TLA+ I     Y ++++++     L +KRD++TKP+P++RRGL
Sbjct: 240 LVRIGHPSRVSSHLKESTLAHQIETSSEYEKVKKMKEELAKLIKKRDSFTKPSPQWRRGL 299

Query: 301 SDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREADV 360
           SD++I++ AE+   ARG+S   I EMAEWIKLN Q+Q   D   + EE IA  I+REA V
Sbjct: 300 SDKKILEYAEKNWSARGVSKEKIKEMAEWIKLNSQIQDIRDLIERKEEIIASRIVREAQV 359

Query: 361 VLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSL 420
           VL+TNSSAALE++    +DV ++DEA+Q+TIPSILIP++K ++FVLAGDHKQLPPTILS 
Sbjct: 360 VLSTNSSAALEILSGIVFDVVVVDEASQATIPSILIPISKGKKFVLAGDHKQLPPTILSE 419

Query: 421 EAQELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRD 480
           +A++LSRTLFE LI RYP KS +L  QYRMNE +MEFPS+EFY GK+ A E VR ITL D
Sbjct: 420 DAKDLSRTLFEELITRYPEKSSLLDTQYRMNELLMEFPSEEFYDGKLKAAEKVRNITLFD 479

Query: 481 L-VEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKL 539
           L VE  +    W  +L+P+NV+VFIDT    +++ERQR+ S SRENPLEA+IV ++V+KL
Sbjct: 480 LGVEIPNFGKFWDVVLSPKNVLVFIDTKNRSDRFERQRKDSPSRENPLEAQIVKEVVEKL 539

Query: 540 LSIGVKPEWIGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNKLGEI 599
           LS+GVK +WIG+ITPYDDQ +LI   +   VEV +VDG+QGREKEVII+S VRSNK GEI
Sbjct: 540 LSMGVKEDWIGIITPYDDQVNLIRELIEAKVEVHSVDGFQGREKEVIIISFVRSNKNGEI 599

Query: 600 GFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGCFIEF 650
           GFL+DLRRLNVSLTRAKRKLI  GDSSTLS H TY++ +EF K+KG ++ F
Sbjct: 600 GFLEDLRRLNVSLTRAKRKLIATGDSSTLSVHPTYRRFVEFVKKKGTYVIF 650


>gi|11498984 DNA helicase, putative [Archaeoglobus fulgidus]
           >gi|7446666|pir||C69423 DNA helicase homolog -
           Archaeoglobus fulgidus >gi|2649188|gb|AAB89860.1|
           (AE001009) DNA helicase, putative [Archaeoglobus
           fulgidus]
           Length = 648
           
 Score =  737 bits (1881), Expect = 0.0
 Identities = 379/644 (58%), Positives = 498/644 (76%), Gaps = 12/644 (1%)

Query: 6   FINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYFLVKYGR 65
           FI  L  L E+ER+A+I AM  E+RRLSG +RER GRA+L L GK++GEELG+ LV+YGR
Sbjct: 4   FIEGLIRLTEVERDAQISAMMDEIRRLSGEKRERKGRAVLGLRGKVVGEELGFKLVRYGR 63

Query: 66  NREIKTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWALRDVRIDLYAN 125
            + I+TEISVGD V+IS+ DPLKSDL G VVEKG R++ V+LE+VPEWALRDVRIDLYA+
Sbjct: 64  RKAIETEISVGDEVLISRGDPLKSDLRGVVVEKGSRYLTVSLESVPEWALRDVRIDLYAS 123

Query: 126 DITFRRWLENLNTIKKAGKRALRFYLGLDEPSQGEEVNFVPFDKSLNRSQRKAISKALGS 185
           D+TF+RW+ENL  + + GKRAL+F LGL+EPS+ E  +F PFD SLNR+Q KA+  A+ +
Sbjct: 124 DLTFKRWIENLENLTENGKRALKFALGLEEPSKTECEDFKPFDSSLNRAQLKAVGCAVST 183

Query: 186 EDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLSRSGIKIVRIG 245
           +DFFL+HGPFGTGKTRT+VE++RQ VKRG +VL TAESN AVDNLVE L  S +KIVR+G
Sbjct: 184 DDFFLIHGPFGTGKTRTVVEVVRQLVKRGERVLVTAESNTAVDNLVELL--SDMKIVRLG 241

Query: 246 HPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGLSDEEI 305
           HPSRV K L E TLA L+  H  Y  + E++   + +  + +  TKP+P+ RRGLSDEEI
Sbjct: 242 HPSRVEKRLKEHTLASLVLNHPDYKRIEEIKGKIEEIERRMERLTKPSPQLRRGLSDEEI 301

Query: 306 IKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREADVVLTTN 365
           ++LA   RGARG++A+ I  MAEWI+  + + + + + ++ EERI ++II E+DVV++TN
Sbjct: 302 LRLARSNRGARGVAAKKIRSMAEWIEARKALDQLYTEMKEEEERIVKEIIEESDVVISTN 361

Query: 366 SSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSLEAQEL 425
           SSA L     +++D A+IDEA+Q+TIPS+LIP+N+  +F+LAGDH+QLPPT+  ++A++L
Sbjct: 362 SSAFLL---EESFDTAVIDEASQATIPSVLIPINRARKFILAGDHRQLPPTV--MKAEKL 416

Query: 426 SRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQ 485
           S TLFE LIE YP KS++L VQYRMNE++MEFPS+EFYGG+I+A ES   I L  + + +
Sbjct: 417 SETLFEKLIELYPEKSQLLNVQYRMNEKLMEFPSREFYGGRIVAHESCTAIALSQIAKRE 476

Query: 486 SPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVK 545
           +  +   +IL  E  +VFIDTSK +N+WE +   S SR N LEAEIV +IV +LL +G+K
Sbjct: 477 A--EKLREILGDE-PLVFIDTSKCKNRWEGKLADSTSRYNRLEAEIVTEIVTELLKMGLK 533

Query: 546 PEWIGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDL 605
            E IGVITPYDDQ DL+  KV  DVEV +VDG+QGREKEVII+S VRSN+  EIGFL DL
Sbjct: 534 KEQIGVITPYDDQVDLLREKV--DVEVSSVDGFQGREKEVIIISFVRSNRKREIGFLDDL 591

Query: 606 RRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGCFIE 649
           RRLNVSLTRA+RKLI+VGDS TLS + TY ++I+  K KG ++E
Sbjct: 592 RRLNVSLTRARRKLIMVGDSETLSVNGTYARLIDHVKRKGVYVE 635


>pir||D69085 transcription control factor enhancer-binding protein -
           Methanobacterium thermoautotrophicum (strain Delta H)
           >gi|2622761|gb|AAB86107.1| (AE000922) transcriptional
           control factor (enhancer-binding protein)
           [Methanobacterium thermoautotrophicum]
           Length = 642
           
 Score =  687 bits (1754), Expect = 0.0
 Identities = 363/631 (57%), Positives = 472/631 (74%), Gaps = 6/631 (0%)

Query: 16  IEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYFLVKYGRNREIKTEISV 75
           +EREAEI AM  E+RRLS  +RER  RA+  LNGKI G ELG+ LVKYGR   I T+ISV
Sbjct: 1   MEREAEISAMMNEIRRLSPRQRERARRAVNGLNGKITGRELGFHLVKYGRRDPIDTQISV 60

Query: 76  GDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWALRDVRIDLYANDITFRRWLEN 135
           GDLV+IS+ +PL+SDL GTV  KGKRF+VVALE VP WAL++VRIDLYAND+TF+R ++N
Sbjct: 61  GDLVLISRGNPLRSDLTGTVAMKGKRFLVVALEHVPGWALKNVRIDLYANDVTFQRMIDN 120

Query: 136 LNTIKKAGKRALRFYLGLDEPSQGEEV-NFVPFDKSLNRSQRKAISKALGSEDFFLVHGP 194
           L +  +   R L F  G ++PS G +V +F   D  LN SQR AI  ALGSEDFFL+HGP
Sbjct: 121 LKSPTRNVLRVLGFLCGTEKPSDGVDVVDFQAVDPELNESQRDAIRMALGSEDFFLIHGP 180

Query: 195 FGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKHL 254
           FGTGKTRTL ELIRQEV RG++VL TAESN AVDNL+E ++   +K VR+GHP RVS+  
Sbjct: 181 FGTGKTRTLHELIRQEVMRGSRVLVTAESNAAVDNLLEGIA-GHVKCVRLGHPQRVSREN 239

Query: 255 HETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRG 314
              TLAY I  H  Y ++RE +     L E+R+ + KPTP+ RRGLSD +I+  A ++RG
Sbjct: 240 LRETLAYKIENHPEYSKVREYQEKIDELIEERERHQKPTPQIRRGLSDTQILINATKRRG 299

Query: 315 ARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREADVVLTTNSSAALEVVD 374
           ARG+S  +++ MA WI+ N+++       ++ E RIA  I+RE+ VVL+TNSSAALE +D
Sbjct: 300 ARGISPNVMISMARWIETNQRIDDLHSKLQEAEMRIADRILRESQVVLSTNSSAALEYID 359

Query: 375 YDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSLEAQELSRTLFEGLI 434
              +DVAI+DEA+Q+TIPSILIPL +  RF+LAGDH+QLPPTILS +A EL RTLFE LI
Sbjct: 360 GLRFDVAIVDEASQATIPSILIPLARAPRFILAGDHRQLPPTILSRDASELERTLFEELI 419

Query: 435 ERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKI 494
           +R+P +S ML  QYRM+  IMEFP++EFY G+I A  S+  I++RD++E    +D   K+
Sbjct: 420 KRHPGRSRMLNCQYRMHPAIMEFPNREFYDGRIRAHPSLEDISIRDIIEDVPDSDICQKL 479

Query: 495 LNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITP 554
            +P+ V+ FIDTS  +   ER+ +GS S +NPLEA++   I   L+ +GVKPE IG+ITP
Sbjct: 480 ADPDPVL-FIDTSGLDG-CERRLKGSTSIQNPLEADLAVIISRSLMRMGVKPEEIGIITP 537

Query: 555 YDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTR 614
           YDDQ DLIS  +  DVEV +VDG+QGREK+VII+S+VRSN+ G IGFLKDLRRLNVSLTR
Sbjct: 538 YDDQVDLISSMI--DVEVNSVDGFQGREKDVIIISMVRSNRNGSIGFLKDLRRLNVSLTR 595

Query: 615 AKRKLIVVGDSSTLSSHETYKKMIEFFKEKG 645
           A+RKLI++GDS TLS+H +Y+++ EF +++G
Sbjct: 596 ARRKLIIIGDSRTLSAHPSYRRLTEFCRKRG 626


>sp|Q57568|Y104_METJA HYPOTHETICAL ATP-BINDING PROTEIN MJ0104 >gi|2129217|pir||H64312
           probable DNA helicase MJ0104 - Methanococcus jannaschii
           >gi|1590880|gb|AAB98084.1| (U67467) DNA-binding protein,
           probably DNA helicase [Methanococcus jannaschii]
           Length = 663
           
 Score =  540 bits (1377), Expect = e-152
 Identities = 298/647 (46%), Positives = 435/647 (67%), Gaps = 23/647 (3%)

Query: 6   FINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYFLVKYGR 65
           ++ +  +L+EIER  E++  + E+ +L G +RE +GRAILNL GK +GE LG  +V++GR
Sbjct: 17  YVKKFMDLIEIERRCEMDFHKNEIIKL-GKKRENVGRAILNLKGKFLGESLGCTIVRFGR 75

Query: 66  NREIKTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALET-VPEWALRD-VRIDLY 123
            +  KTEIS GD+V++SK +PL+SDL   V+  GK FI VA +  VP+W  ++ VR+DLY
Sbjct: 76  KKPFKTEISPGDVVLVSKENPLQSDLYANVIYVGKNFIDVAFDVDVPKWVYKERVRVDLY 135

Query: 124 ANDITFRRWLENLNTIKKAGKRALRFYLGLDEPSQG--EEVNFVPFDKSLNRSQRKAISK 181
            NDITF+R  E L    +   +     LG++ P +   E++    +DK+LN SQ+ A+ K
Sbjct: 136 VNDITFKRMKEALREFARKRDKLAYIILGIEHPEKPLREDIKLEFYDKNLNESQKLAVKK 195

Query: 182 ALGSEDFFLVHGPFGTGKTRTLVELIRQEVK-RGNKVLATAESNVAVDNLVERLSRS--G 238
           A+ S D +L+HGP GTGKTRT+ E+I QEVK   +KVLATA+SN+A DN++E L +    
Sbjct: 196 AVLSRDLYLIHGPPGTGKTRTITEVIVQEVKFNKHKVLATADSNIAADNILEYLIKKYPD 255

Query: 239 IKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRR 298
           +K+VR+GHP+R+SK L + +L YLI  HE Y E+  LR   + + E+RD + KP+P++RR
Sbjct: 256 LKVVRVGHPTRISKDLIQHSLPYLIENHEKYQEILALREKIKEIKEQRDKFLKPSPRWRR 315

Query: 299 GLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREA 358
           G+SDE+I+K+A+RK+  RG+    I+ MAEWI  N+++++  ++  ++ E+I  +I+ EA
Sbjct: 316 GMSDEQILKVAKRKKSYRGIPKEKIVSMAEWIIRNKKIKRIINNLDEITEKIMNEILAEA 375

Query: 359 DVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTIL 418
           DV++ TNS A  E++    +DV +IDE +Q+  PS LIP+ K  + ++AGDHKQLPPT+L
Sbjct: 376 DVIVATNSMAGSEILKGWEFDVIVIDEGSQAMEPSCLIPIVKGRKLIMAGDHKQLPPTVL 435

Query: 419 SLEAQELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITL 478
           S E +EL +TLFE LI++YP  S +L +QYRMNE+IMEFP+K FY  K+ ADESV+ ITL
Sbjct: 436 S-ENEELKKTLFERLIKKYPEFSSILEIQYRMNEKIMEFPNKMFYNNKLKADESVKNITL 494

Query: 479 RDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDK 538
            DLV+ +  ++    I+N E  + FI+        ER+ + S S  N  EAE V +IV K
Sbjct: 495 LDLVKEEEIDEVDRDIIN-EIPVQFINVEGI----ERKDKESPSYYNIEEAEKVLEIVKK 549

Query: 539 LLSIGVKPEWIGVITPYDDQRDLISMKVPE---DVEVKTVDGYQGREKEVIILSLVRSNK 595
           L+   +      VITPYD Q   +     E   D+EV TVDG+QGRE E I++S VR+  
Sbjct: 550 LVKYKIP---TNVITPYDAQVRYLRRLFEEHNIDIEVNTVDGFQGRENEAIVISFVRTK- 605

Query: 596 LGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFK 642
               GFLKDLRRLNV++TRAKRKLI++G+ + L   + Y +MI++ K
Sbjct: 606 --NFGFLKDLRRLNVAITRAKRKLILIGNENLLKQDKVYNEMIKWAK 650


>pir||D70476 DNA helicase - Aquifex aeolicus >gi|2984278|gb|AAC07803.1|
           (AE000770) DNA helicase [Aquifex aeolicus]
           Length = 530
           
 Score =  461 bits (1174), Expect = e-129
 Identities = 251/484 (51%), Positives = 342/484 (69%), Gaps = 10/484 (2%)

Query: 171 LNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNL 230
           LN  Q+KA+ +AL +E  FL+HGP GTGKT TLVE I++  + G KVLATA+SNVAVDNL
Sbjct: 49  LNAYQKKAVERALKAEKVFLIHGPPGTGKTTTLVECIKRLAQEGYKVLATADSNVAVDNL 108

Query: 231 VERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYT 290
           VERL R  +K+VR+G+P RV K +   TL YL+     + + R++     +L E++  Y 
Sbjct: 109 VERLVRENVKVVRVGNPVRVLKTIQRHTLDYLVQFEPEFDKARKIYEEIDNLKEEQKKYV 168

Query: 291 KPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERI 350
           KP P++RRGLSDEEI+K A+     RGLS +++  MA+WIKL  +V++ ++ A+K EE+ 
Sbjct: 169 KPEPRYRRGLSDEEILKRAKTGTPVRGLSPKILRSMAKWIKLQEKVKELYEKAKKEEEKA 228

Query: 351 ARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDH 410
              I+  A VV TTNS+A  EV+    +DV IIDEATQ+T PS LIPL K ++ ++AGDH
Sbjct: 229 VNKILSRAQVVCTTNSTAGSEVLQNLNFDVVIIDEATQATEPSCLIPLIKGKKLIMAGDH 288

Query: 411 KQLPPTILSLEAQE-LSRTLFEGLIERYPWK-SEMLVVQYRMNERIMEFPSKEFYGGKII 468
           KQLPPT+LS EAQE LS TLFE L++ Y  +  E+L +QYRMN++IMEF +K FY GK+I
Sbjct: 289 KQLPPTVLSQEAQEALSYTLFERLLDLYGEEIYEILRIQYRMNKKIMEFSNKMFYEGKLI 348

Query: 469 ADESVRGITLRDLV---EYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESREN 525
           AD+SV   T++DL+   + +   + +  +L PE V+VFI+        E+QRRGS S  N
Sbjct: 349 ADKSVENHTIKDLINPEKLKEIPEPFKSVLEPEKVVVFINVRGK----EKQRRGSTSFYN 404

Query: 526 PLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE-DVEVKTVDGYQGREKE 584
             EA++  KIV+ L+ IG++ E IGVI+PY+DQ + +   + + +VEVKTVDG+QGREKE
Sbjct: 405 EEEAKVAVKIVEYLMKIGLRSEHIGVISPYEDQVNFLEELLKDFEVEVKTVDGFQGREKE 464

Query: 585 VIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEK 644
           VII+S VRSN+ GEIGFLKD RRLNV+LTRA+RKLI +G+  TLSS E YK+ I + K  
Sbjct: 465 VIIISFVRSNEKGEIGFLKDYRRLNVALTRARRKLITLGNEKTLSSDEVYKQFIGYVKSI 524

Query: 645 GCFI 648
           G +I
Sbjct: 525 GGYI 528


>pir||T02699 hypothetical protein T18E12.6 - Arabidopsis thaliana
           >gi|4335770|gb|AAD17447.1| (AC006284) putative helicase
           [Arabidopsis thaliana]
           Length = 635
           
 Score =  352 bits (894), Expect = 6e-96
 Identities = 249/672 (37%), Positives = 377/672 (56%), Gaps = 68/672 (10%)

Query: 1   MNITSFINRLKELVEIEREAEIEAMRLEMRRLSGIER-ERLGRAILNLNGKIIGEEL-GY 58
           M++ +F++ +  L+++E+EAEI +M L       IE  ++ G  ILNL    +   L G 
Sbjct: 1   MSLEAFVSTMAPLIDMEKEAEI-SMSLTSGASRNIETAQKKGTTILNLKCVDVQTGLMGK 59

Query: 59  FLVKYGRNR-EIKTEISVG--DLVVI--SKRDPLKSDLLGTVVEKGK-RFIVVALETVPE 112
            L+++  N+ ++      G  D+VV+  +K D   S L   VV + K   I V  + VPE
Sbjct: 60  SLIEFQSNKGDVLPAHKFGNHDVVVLKLNKSDLGSSPLAQGVVYRLKDSSITVVFDEVPE 119

Query: 113 WALR-DVRIDLYANDITFRRWLENLNTIKKAGKRA-----LRFYLGLDEPSQGEE--VNF 164
             L   +R++  AN++T+RR  + L  + K   R      +    G  +PS  ++   +F
Sbjct: 120 EGLNTSLRLEKLANEVTYRRMKDTLIQLSKGVLRGPASDLVPVLFGERQPSVSKKDVKSF 179

Query: 165 VPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESN 224
            PF+K+L++SQ+ AI+KAL S+D FL+HGP GTGKT T+VE++ QEVKRG+K+LA A SN
Sbjct: 180 TPFNKNLDQSQKDAITKALSSKDVFLLHGPPGTGKTTTVVEIVLQEVKRGSKILACAASN 239

Query: 225 VAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAE 284
           +AVDN+VERL    +K+VR+GHP+R+   + ++ L   + + +  G   ++R   ++L  
Sbjct: 240 IAVDNIVERLVPHKVKLVRVGHPARLLPQVLDSALDAQVLKGDNSGLANDIRKEMKALNG 299

Query: 285 KRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDAR 344
           K     K   K  R L  +E+  L +                               + R
Sbjct: 300 K---LLKAKDKNTRRLIQKELRTLGK-------------------------------EER 325

Query: 345 KLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERF 404
           K ++    D+I+ ADV+LTT + A    +D  T+D+ IIDE  Q+   +  I L K  R 
Sbjct: 326 KRQQLAVSDVIKNADVILTTLTGALTRKLDNRTFDLVIIDEGAQALEVACWIALLKGSRC 385

Query: 405 VLAGDHKQLPPTILSLEAQE--LSRTLFEGLIERYPWK-SEMLVVQYRMNERIMEFPSKE 461
           +LAGDH QLPPTI S EA+   L RTLFE L + Y  +   ML VQYRM+E IM + SKE
Sbjct: 386 ILAGDHLQLPPTIQSAEAERKGLGRTLFERLADLYGDEIKSMLTVQYRMHELIMNWSSKE 445

Query: 462 FYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSE 521
            Y  KI A  SV    L DL       ++  K  + E  ++ +DT+  +   E ++   E
Sbjct: 446 LYDNKITAHSSVASHMLFDL-------ENVTKSSSTEATLLLVDTAGCD--MEEKKDEEE 496

Query: 522 SRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISM-----KVPEDVEVKTVD 576
           S  N  EAE+      +L+  GV+P  IG+ITPY  Q  L+ +     +  +D+E+ TVD
Sbjct: 497 STYNEGEAEVAMAHAKRLMESGVQPSDIGIITPYAAQVMLLRILRGKEEKLKDMEISTVD 556

Query: 577 GYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKK 636
           G+QGREKE II+S+VRSN   E+GFLKD RR+NV++TR++R+  +V D+ T+SS    K+
Sbjct: 557 GFQGREKEAIIISMVRSNSKKEVGFLKDQRRMNVAVTRSRRQCCIVCDTETVSSDAFLKR 616

Query: 637 MIEFFKEKGCFI 648
           MIE+F+E G ++
Sbjct: 617 MIEYFEEHGEYL 628


>emb|CAC16347.1| (AJ300306) putative helicase [Arabidopsis thaliana]
           Length = 635
           
 Score =  351 bits (891), Expect = 1e-95
 Identities = 248/672 (36%), Positives = 375/672 (54%), Gaps = 68/672 (10%)

Query: 1   MNITSFINRLKELVEIEREAEIEAMRLEMRRLSGIER-ERLGRAILNLNGKIIGEEL-GY 58
           M++ +F++ +  L+++E+EAEI +M L       IE  ++ G  ILNL    +   L G 
Sbjct: 1   MSLEAFVSTMAPLIDMEKEAEI-SMSLTSGASRNIETAQKKGTTILNLKCVDVQTGLMGK 59

Query: 59  FLVKYGRNREIKT---EISVGDLVVI--SKRDPLKSDLLGTVVEKGK-RFIVVALETVPE 112
            L+++  N+       +    D+VV+  +K D   S L   VV + K   I V  + VPE
Sbjct: 60  SLIEFQSNKGDALPAHKFGNHDVVVLKLNKSDLGSSPLAQGVVYRLKDSSITVVFDEVPE 119

Query: 113 WALR-DVRIDLYANDITFRRWLENLNTIKKAGKRA-----LRFYLGLDEPSQGEE--VNF 164
             L   +R++  AN++T+RR  + L  + K   R      +    G  +PS  ++   +F
Sbjct: 120 EGLNTSLRLEKLANEVTYRRMKDTLIQLSKGVLRGPASDLVPVLFGERQPSVSKKDVKSF 179

Query: 165 VPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESN 224
            PF+K+L++SQ+ AI+KAL S+D FL+HGP GTGKT T+VE++ QEVKRG+K+LA A SN
Sbjct: 180 TPFNKNLDQSQKDAITKALSSKDVFLLHGPPGTGKTTTVVEIVLQEVKRGSKILACAASN 239

Query: 225 VAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAE 284
           +AVDN+VERL    +K+VR+GHP+R+   + ++ L   + + +  G   ++R   ++L  
Sbjct: 240 IAVDNIVERLVPHKVKLVRVGHPARLLPQVLDSALDAQVLKGDNSGLANDIRKEMKALNG 299

Query: 285 KRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDAR 344
           K     K   K  R L  +E+  L +                               + R
Sbjct: 300 K---LLKAKDKNTRRLIQKELRTLGK-------------------------------EER 325

Query: 345 KLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERF 404
           K ++    D+I+ ADV+LTT + A    +D  T+D+ IIDE  Q+   +  I L K  R 
Sbjct: 326 KRQQLAVSDVIKNADVILTTLTGALTRKLDNRTFDLVIIDEGAQALEVACWIALLKGSRC 385

Query: 405 VLAGDHKQLPPTILSLEAQE--LSRTLFEGLIERYPWK-SEMLVVQYRMNERIMEFPSKE 461
           +LAGDH QLPPTI S EA+   L RTLFE L + Y  +   ML VQYRM+E IM + SKE
Sbjct: 386 ILAGDHLQLPPTIQSAEAERKGLGRTLFERLADLYGDEIKSMLTVQYRMHELIMNWSSKE 445

Query: 462 FYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSE 521
            Y  KI A  SV    L DL       ++  K  + E  ++ +DT+  +   E ++   E
Sbjct: 446 LYDNKITAHSSVASHMLFDL-------ENVTKSSSTEATLLLVDTAGCD--MEEKKDEEE 496

Query: 522 SRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISM-----KVPEDVEVKTVD 576
           S  N  EAE+      +L+  GV+P  IG+ITPY  Q  L+ +     +  +D+E+ TVD
Sbjct: 497 STYNEGEAEVAMAHAKRLMESGVQPSDIGIITPYAAQVMLLRILRGKEEKLKDMEISTVD 556

Query: 577 GYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKK 636
           G+QGREKE II+S+VRSN   E+GFLKD RR+NV++TR++R+  +V D+ T+SS    K+
Sbjct: 557 GFQGREKEAIIISMVRSNSKKEVGFLKDQRRMNVAVTRSRRQCCIVCDTETVSSDAFLKR 616

Query: 637 MIEFFKEKGCFI 648
           MIE+F+E G ++
Sbjct: 617 MIEYFEEHGEYL 628


>gb|AAG28561.1|AF199411_1 (AF199411) antifreeze-enhancer binding protein AEP [Rattus
           norvegicus]
           Length = 988
           
 Score =  300 bits (760), Expect = 3e-80
 Identities = 225/676 (33%), Positives = 360/676 (52%), Gaps = 81/676 (11%)

Query: 3   ITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYF--- 59
           + SF+ +  +L+E+ER+AE+E  R      S  E +  G  +L L  ++ G+  G +   
Sbjct: 6   VESFVAQQLQLLELERDAEVEERRSWQEHSSLKELQSRGVCLLKL--QVSGQRTGLYGQR 63

Query: 60  LV-----KYGRNREIKTE-ISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEW 113
           LV     K+G    + +   + GD+V +   +       G +    ++ ++VA +   ++
Sbjct: 64  LVTFEPRKFGPAVVLPSNSFTSGDIVGLYDTNESSQLATGVLTRITQKSVIVAFDESHDF 123

Query: 114 ALRDVRIDLY-----ANDITFRRWLENLNTIKK----AGKRALRFYLGLDEPSQGEEVNF 164
            L   R + Y     AND+T++R  + L T+KK         +   LG   PS   E+  
Sbjct: 124 QLNLDRENTYRLLKLANDVTYKRLKKALLTLKKYHSGPASSLIDVLLGGSTPSPATEIPP 183

Query: 165 VPF-DKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAES 223
           + F + +L+ SQ++A+S AL  ++  ++HGP GTGKT T+VE+I Q VK+G KVL  A S
Sbjct: 184 LTFYNTTLDPSQKEAVSFALAQKEVAIIHGPPGTGKTTTVVEIILQAVKQGLKVLCCAPS 243

Query: 224 NVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQH---ELYGELRELRVIGQ 280
           N+AVDNLVERL+    +I+R+GHP+R+ + + + +L  ++ +    ++  ++R  R I Q
Sbjct: 244 NIAVDNLVERLALCKKQILRLGHPARLLESVQQHSLDAVLARSDNAQIVADIR--RDIDQ 301

Query: 281 SLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAF 340
              + + T  K     R   +    IKL  +                             
Sbjct: 302 VFGKNKKTQDK-----REKSNFRNEIKLLRK----------------------------- 327

Query: 341 DDARKLEERIARDIIREADVVLTTNSSAA----LEVVDYDTYDVAIIDEATQSTIPSILI 396
            + ++ EE      +  ADVVL TN+ A+    L+++  D +DV ++DE  Q+   S  I
Sbjct: 328 -ELKEREEAAIVQSLSAADVVLATNTGASTDGPLKLLPEDYFDVVVVDECAQALEASCWI 386

Query: 397 PLNKVERFVLAGDHKQLPPTILSLEA--QELSRTLFEGLIERY-PWKSEMLVVQYRMNER 453
           PL K  + +LAGDHKQLPPT +S +A    LSR+L E L E++      ML VQYRM++ 
Sbjct: 387 PLLKAPKCILAGDHKQLPPTTVSHKAALAGLSRSLMERLAEKHGAAVVRMLAVQYRMHQA 446

Query: 454 IMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKW 513
           I  + S+  Y G++ A  SV G  L+DL       ++   +L        IDT+      
Sbjct: 447 ITRWASEAMYHGQLTAHPSVAGHLLKDLPGVADTEETSVPLL-------LIDTAGC-GLL 498

Query: 514 ERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDL----ISMKVPED 569
           E +   S+S+ NP E  +V   +  L+  GV+   I VI PY+ Q DL    +S K PE 
Sbjct: 499 ELEEEDSQSKGNPGEVRLVTLHIQALVDAGVQAGDIAVIAPYNLQVDLLRQSLSNKHPE- 557

Query: 570 VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLS 629
           +E+K+VDG+QGREKE +IL+ VRSN+ GE+GFL + RR+NV++TRA+R + V+ DS T++
Sbjct: 558 LEIKSVDGFQGREKEAVILTFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSHTVN 617

Query: 630 SHETYKKMIEFFKEKG 645
           +H   K ++++F E G
Sbjct: 618 NHAFLKTLVDYFTEHG 633


>gi|4504623 immunoglobulin mu binding protein 2 [Homo sapiens]
           >gi|730751|sp|P38935|SMB2_HUMAN DNA-BINDING PROTEIN
           SMUBP-2 (IMMUNOGLOBULIN MU BINDING PROTEIN 2) (SMUBP-2)
           (GLIAL FACTOR-1) (GF-1) >gi|401776|gb|AAA53082.1|
           (L14754) DNA-binding protein [Homo sapiens]
           Length = 993
           
 Score =  299 bits (757), Expect = 7e-80
 Identities = 221/677 (32%), Positives = 357/677 (52%), Gaps = 82/677 (12%)

Query: 3   ITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYF--- 59
           + SF+ +  +L+E+ER+AE+E  R     +S  E +  G  +L L  ++  +  G +   
Sbjct: 6   VESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKL--QVSSQRTGLYGRL 63

Query: 60  LV-----KYGRNREIKTE-ISVGDLVVI----SKRDPLKSDLLGTVVEKGKRFIVVALET 109
           LV     +YG    + +   + GD+V +    ++   L + +L  V +K    + VA + 
Sbjct: 64  LVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKS---VTVAFDE 120

Query: 110 VPEWALRDVRIDLY-----ANDITFRRWLENLNTIKK----AGKRALRFYLGLDEPSQGE 160
             ++ L   R + Y     AND+T+RR  + L  +KK         +    G   PS   
Sbjct: 121 SHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPAS 180

Query: 161 EVNFVPF-DKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLA 219
           E++ + F +  L+ SQ++A+S AL  ++  ++HGP GTGKT T+VE+I Q VK+G KVL 
Sbjct: 181 EIHPLTFFNTCLDTSQKEAVSFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLC 240

Query: 220 TAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRV-I 278
            A SN+AVDNLVERL+    +I+R+GHP+R+ + + + +L  ++ + +    + ++R  I
Sbjct: 241 CAPSNIAVDNLVERLALCKQRILRLGHPARLLESVQQHSLDAVLARSDSAQNVADIRKDI 300

Query: 279 GQSLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQK 338
            Q   + + T  K                             R        IKL R+  K
Sbjct: 301 DQVFVKNKKTQDK-----------------------------REKSNFRNEIKLLRKELK 331

Query: 339 AFDDARKLEERIARDIIREADVVLTTNSSAA----LEVVDYDTYDVAIIDEATQSTIPSI 394
             ++A  LE       +  A+VVL TN+ A+    L+++    +DV +IDE  Q+   S 
Sbjct: 332 EREEAAMLES------LTSANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASC 385

Query: 395 LIPLNKVERFVLAGDHKQLPPTILSLEA--QELSRTLFEGLIERYPWK-SEMLVVQYRMN 451
            IPL K  + +LAGDHKQLPPT +S +A    LS +L E L E Y  +    L VQYRM+
Sbjct: 386 WIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLAEEYGARVVRTLTVQYRMH 445

Query: 452 ERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAEN 511
           + IM + S   Y G++ A  SV    LRDL    +  ++   +L        +DT+    
Sbjct: 446 QAIMRWASDTMYLGQVTAHSSVARHLLRDLPGVAATEETGVPLL-------LVDTAGC-G 497

Query: 512 KWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE--- 568
            +E +    +S+ NP E  +V+  +  L+  GV    I V++PY+ Q DL+   +     
Sbjct: 498 LFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRHP 557

Query: 569 DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL 628
           ++E+K+VDG+QGREKE +ILS VRSN+ GE+GFL + RR+NV++TRA+R + V+ DS T+
Sbjct: 558 ELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTV 617

Query: 629 SSHETYKKMIEFFKEKG 645
           ++H   K ++E+F + G
Sbjct: 618 NNHAFLKTLVEYFTQHG 634


>pir||A47500 Ig mu chain switch region binding protein 2 - human
           Length = 993
           
 Score =  299 bits (757), Expect = 7e-80
 Identities = 221/677 (32%), Positives = 357/677 (52%), Gaps = 82/677 (12%)

Query: 3   ITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYF--- 59
           + SF+ +  +L+E+ER+AE+E  R     +S  E +  G  +L L  ++  +  G +   
Sbjct: 6   VESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKL--QVSSQRTGLYGRL 63

Query: 60  LV-----KYGRNREIKTE-ISVGDLVVI----SKRDPLKSDLLGTVVEKGKRFIVVALET 109
           LV     +YG    + +   + GD+V +    ++   L + +L  V +K    + VA + 
Sbjct: 64  LVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKS---VTVAFDE 120

Query: 110 VPEWALRDVRIDLY-----ANDITFRRWLENLNTIKK----AGKRALRFYLGLDEPSQGE 160
             ++ L   R + Y     AND+T+RR  + L  +KK         +    G   PS   
Sbjct: 121 SHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPAS 180

Query: 161 EVNFVPF-DKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLA 219
           E++ + F +  L+ SQ++A+S AL  ++  ++HGP GTGKT T+VE+I Q VK+G KVL 
Sbjct: 181 EIHPLTFFNTCLDTSQKEAVSFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLC 240

Query: 220 TAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRV-I 278
            A SN+AVDNLVERL+    +I+R+GHP+R+ + + + +L  ++ + +    + ++R  I
Sbjct: 241 CAPSNIAVDNLVERLALCKQRILRLGHPARLLESVQQHSLDAVLARSDSAQNVADIRKDI 300

Query: 279 GQSLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQK 338
            Q   + + T  K                             R        IKL R+  K
Sbjct: 301 DQVFVKNKKTQDK-----------------------------REKSNFRNEIKLLRKELK 331

Query: 339 AFDDARKLEERIARDIIREADVVLTTNSSAA----LEVVDYDTYDVAIIDEATQSTIPSI 394
             ++A  LE       +  A+VVL TN+ A+    L+++    +DV +IDE  Q+   S 
Sbjct: 332 EREEAAMLES------LTSANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASC 385

Query: 395 LIPLNKVERFVLAGDHKQLPPTILSLEA--QELSRTLFEGLIERYPWK-SEMLVVQYRMN 451
            IPL K  + +LAGDHKQLPPT +S +A    LS +L E L E Y  +    L VQYRM+
Sbjct: 386 WIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLAEEYGARVVRTLTVQYRMH 445

Query: 452 ERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAEN 511
           + IM + S   Y G++ A  SV    LRDL    +  ++   +L        +DT+    
Sbjct: 446 QAIMRWASDTMYLGQVTAHSSVARHLLRDLPGVAATEETGVPLL-------LVDTAGC-G 497

Query: 512 KWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE--- 568
            +E +    +S+ NP E  +V+  +  L+  GV    I V++PY+ Q DL+   +     
Sbjct: 498 LFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRHP 557

Query: 569 DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL 628
           ++E+K+VDG+QGREKE +ILS VRSN+ GE+GFL + RR+NV++TRA+R + V+ DS T+
Sbjct: 558 ELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTV 617

Query: 629 SSHETYKKMIEFFKEKG 645
           ++H   K ++E+F + G
Sbjct: 618 NNHAFLKTLVEYFTQHG 634


>gi|11435569 immunoglobulin mu binding protein 2 [Homo sapiens]
           Length = 731
           
 Score =  298 bits (754), Expect = 2e-79
 Identities = 221/677 (32%), Positives = 357/677 (52%), Gaps = 82/677 (12%)

Query: 3   ITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYF--- 59
           + SF+ +  +L+E+ER+AE+E  R     +S  E +  G  +L L  ++  +  G +   
Sbjct: 6   VESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKL--QVSSQRTGLYGRL 63

Query: 60  LV-----KYGRNREIKTE-ISVGDLVVI----SKRDPLKSDLLGTVVEKGKRFIVVALET 109
           LV     +YG    + +   + GD+V +    ++   L + +L  V +K    + VA + 
Sbjct: 64  LVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKS---VTVAFDE 120

Query: 110 VPEWALRDVRIDLY-----ANDITFRRWLENLNTIKK----AGKRALRFYLGLDEPSQGE 160
             ++ L   R + Y     AND+T+RR  + L  +KK         +    G   PS   
Sbjct: 121 SHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPAS 180

Query: 161 EVNFVPF-DKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLA 219
           E++ + F +  L+ SQ++A+S AL  ++  ++HGP GTGKT T+VE+I Q VK+G KVL 
Sbjct: 181 EIHPLTFFNTCLDTSQKEAVSFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLC 240

Query: 220 TAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRV-I 278
            A SN+AVDNLVERL+    +I+R+GHP+R+ + + + +L  ++ + +    + ++R  I
Sbjct: 241 CAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDI 300

Query: 279 GQSLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQK 338
            Q   + + T  K                             R        IKL R+  K
Sbjct: 301 DQVFVKNKKTQDK-----------------------------REKSNFRNEIKLLRKELK 331

Query: 339 AFDDARKLEERIARDIIREADVVLTTNSSAA----LEVVDYDTYDVAIIDEATQSTIPSI 394
             ++A  LE       +  A+VVL TN+ A+    L+++    +DV +IDE  Q+   S 
Sbjct: 332 EREEAAMLES------LTSANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASC 385

Query: 395 LIPLNKVERFVLAGDHKQLPPTILSLEA--QELSRTLFEGLIERYPWK-SEMLVVQYRMN 451
            IPL K  + +LAGDHKQLPPT +S +A    LS +L E L E Y  +    L VQYRM+
Sbjct: 386 WIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLAEEYGARVVRTLTVQYRMH 445

Query: 452 ERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAEN 511
           + IM + S   Y G++ A  SV    LRDL    +  ++   +L        +DT+    
Sbjct: 446 QAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATEETGVPLL-------LVDTAGC-G 497

Query: 512 KWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE--- 568
            +E +    +S+ NP E  +V+  +  L+  GV    I V++PY+ Q DL+   +     
Sbjct: 498 LFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRHP 557

Query: 569 DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL 628
           ++E+K+VDG+QGREKE +ILS VRSN+ GE+GFL + RR+NV++TRA+R + V+ DS T+
Sbjct: 558 ELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTV 617

Query: 629 SSHETYKKMIEFFKEKG 645
           ++H   K ++E+F + G
Sbjct: 618 NNHAFLKTLVEYFTQHG 634


>sp|Q60560|SMB2_MESAU DNA-BINDING PROTEIN SMUBP-2 (IMMUNOGLOBULIN MU BINDING PROTEIN 2)
           (SMUBP-2) (INSULIN II GENE ENHANCER-BINDING PROTEIN)
           (RIPE3B-BINDING COMPLEX 3B2 P110 SUBUNIT) (RIP-1)
           >gi|11360343|pir||T48845 insulin II gene
           enhancer-binding protein rip1 [validated] - golden
           hamster >gi|290919|gb|AAB00104.1| (L15625) insulin II
           gene enhancer-binding protein [Mesocricetus auratus]
           Length = 989
           
 Score =  296 bits (750), Expect = 5e-79
 Identities = 223/678 (32%), Positives = 353/678 (51%), Gaps = 85/678 (12%)

Query: 3   ITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYFLVK 62
           + SF+ +  EL+E+ER+AE+E  R      S  E +  G  +L L  ++  +  G     
Sbjct: 6   VESFVAQQLELLELERDAEVEERRSWQEHSSLKELQSRGVCLLKL--QVSSQCTGL---- 59

Query: 63  YGRNREIKTEISVGDLVVISKRDPLKSDLLG-------------TVVEKGKRFIVVALET 109
           YG+         +G +VV+        D++G              +    ++ + VA + 
Sbjct: 60  YGQRLVTFEPRKLGPVVVLPSNSFTSGDIVGLYDANESSQLATGVLTRITQKSVTVAFDE 119

Query: 110 VPEWALRDVRIDLY-----ANDITFRRWLENLNTIKK----AGKRALRFYLGLDEPSQGE 160
             ++ L   R + Y     AND+T++R  + L T+KK         +   LG   PS   
Sbjct: 120 SHDFQLNLDRENTYRLLKLANDVTYKRLKKALMTLKKYHSGPASSLIDVLLGGSSPSPTT 179

Query: 161 EVN-FVPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLA 219
           E+  F  ++ +L+ SQ++A+S AL  ++  ++HGP GTGKT T+VE+I Q VK+G K+L 
Sbjct: 180 EIPPFTFYNTALDPSQKEAVSFALAQKEVAIIHGPPGTGKTTTVVEIILQAVKQGLKILC 239

Query: 220 TAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRV-I 278
            A SNVAVDNLVERL+    +I+R+GHP+R+ +   + +L  ++ + +    + ++R  I
Sbjct: 240 CAPSNVAVDNLVERLALCKKRILRLGHPARLLESAQQHSLDAVLARSDNAQIVADIRKDI 299

Query: 279 GQSLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQK 338
            Q   + + T  K                             R        IKL R+  K
Sbjct: 300 DQVFGKNKKTQDK-----------------------------REKSNFRNEIKLLRKELK 330

Query: 339 AFDDARKLEERIARDIIREADVVLTTNSSAA----LEVVDYDTYDVAIIDEATQSTIPSI 394
             ++A  ++   A      ADVVL TN+ A+    L+++  + +DV ++DE  Q+   S 
Sbjct: 331 EREEAAIVQSLTA------ADVVLATNTGASSDGPLKLLPENHFDVVVVDECAQALEASC 384

Query: 395 LIPLNKVERFVLAGDHKQLPPTILSLEA--QELSRTLFEGLIERY-PWKSEMLVVQYRMN 451
            IPL K  + +LAGDH+QLPPT +S +A    LSR+L E L+E++      ML VQYRM+
Sbjct: 385 WIPLLKAPKCILAGDHRQLPPTTISHKAALAGLSRSLMERLVEKHGAGAVRMLTVQYRMH 444

Query: 452 ERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAEN 511
           + I  + S+  Y G++ A  SV G  L+DL       ++   +L        IDT+    
Sbjct: 445 QAITRWASEAMYHGQLTAHPSVAGHLLKDLPGVADTEETSVPLL-------LIDTAGC-G 496

Query: 512 KWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDL----ISMKVP 567
             E     S+S+ NP E  +V   +  L+  GV    I VI PY+ Q DL    +S K P
Sbjct: 497 LLELDEEDSQSKGNPGEVRLVTLHIQALVDAGVHAGDIAVIAPYNLQVDLLRQSLSNKHP 556

Query: 568 EDVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSST 627
           E +E+K+VDG+QGREKE +IL+ VRSN+ GE+GFL + RR+NV++TRA+R + V+ DS T
Sbjct: 557 E-LEIKSVDGFQGREKEAVILTFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRT 615

Query: 628 LSSHETYKKMIEFFKEKG 645
           +++H   K ++++F E G
Sbjct: 616 VNNHAFLKTLVDYFTEHG 633


>gb|AAA70430.1| (L24544) DNA helicase [Homo sapiens]
           Length = 993
           
 Score =  295 bits (748), Expect = 8e-79
 Identities = 220/677 (32%), Positives = 356/677 (52%), Gaps = 82/677 (12%)

Query: 3   ITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYF--- 59
           + SF+ +  +L+E+ER+AE+E  R     +S  E +  G  +L L  ++  +  G +   
Sbjct: 6   VESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKL--QVSSQRTGLYGRL 63

Query: 60  LV-----KYGRNREIKTE-ISVGDLVVI----SKRDPLKSDLLGTVVEKGKRFIVVALET 109
           LV     +YG    + +   + GD+V +    ++   L + +L  V +K    + VA + 
Sbjct: 64  LVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKS---VTVAFDE 120

Query: 110 VPEWALRDVRIDLY-----ANDITFRRWLENLNTIKK----AGKRALRFYLGLDEPSQGE 160
             ++ L   R + Y     AND+T+RR  + L  +KK         +    G   PS   
Sbjct: 121 SHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPAS 180

Query: 161 EVNFVPF-DKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLA 219
           E++ + F +  L+ SQ++A+  AL  ++  ++HGP GTGKT T+VE+I Q VK+G KVL 
Sbjct: 181 EIHPLTFFNTCLDTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLC 240

Query: 220 TAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRV-I 278
            A SN+AVDNLVERL+    +I+R+GHP+R+ + + + +L  ++ + +    + ++R  I
Sbjct: 241 CAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDI 300

Query: 279 GQSLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQK 338
            Q   + + T  K                             R        IKL R+  K
Sbjct: 301 DQVFVKNKKTQDK-----------------------------REKSNFRNEIKLLRKELK 331

Query: 339 AFDDARKLEERIARDIIREADVVLTTNSSAA----LEVVDYDTYDVAIIDEATQSTIPSI 394
             ++A  LE       +  A+VVL TN+ A+    L+++    +DV +IDE  Q+   S 
Sbjct: 332 EREEAAMLES------LTSANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASC 385

Query: 395 LIPLNKVERFVLAGDHKQLPPTILSLEA--QELSRTLFEGLIERYPWK-SEMLVVQYRMN 451
            IPL K  + +LAGDHKQLPPT +S +A    LS +L E L E Y  +    L VQYRM+
Sbjct: 386 WIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLAEEYGARVVRTLTVQYRMH 445

Query: 452 ERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAEN 511
           + IM + S   Y G++ A  SV    LRDL    +  ++   +L        +DT+    
Sbjct: 446 QAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATEETGVPLL-------LVDTAGC-G 497

Query: 512 KWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE--- 568
            +E +    +S+ NP E  +V+  +  L+  GV    I V++PY+ Q DL+   +     
Sbjct: 498 LFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRHP 557

Query: 569 DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL 628
           ++E+K+VDG+QGREKE +ILS VRSN+ GE+GFL + RR+NV++TRA+R + V+ DS T+
Sbjct: 558 ELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTV 617

Query: 629 SSHETYKKMIEFFKEKG 645
           ++H   K ++E+F + G
Sbjct: 618 NNHAFLKTLVEYFTQHG 634


>gi|6678029 immunoglobulin S mu binding protein 2 [Mus musculus]
           >gi|730752|sp|P40694|SMB2_MOUSE DNA-BINDING PROTEIN
           SMUBP-2 (IMMUNOGLOBULIN MU BINDING PROTEIN 2) (SMUBP-2)
           (CARDIAC TRANSCRIPTION FACTOR 1) (CATF1)
           >gi|423421|pir||S35633 DNA-binding protein - mouse
           >gi|293806|gb|AAA40143.1| (L10075) DNA-binding protein
           [Mus musculus]
           Length = 993
           
 Score =  294 bits (746), Expect = 1e-78
 Identities = 224/674 (33%), Positives = 357/674 (52%), Gaps = 77/674 (11%)

Query: 3   ITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGK-----IIGEELG 57
           + SF+ +  +L+E+ER+AE+E  R      S  E +  G  +L L        + G+ L 
Sbjct: 6   VESFVAQQLQLLELERDAEVEERRSWQEHSSLRELQSRGVCLLKLQVSSQRTGLYGQRLV 65

Query: 58  YFLV-KYGRNREIKTE-ISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWAL 115
            F   K+G    + +   + GD+V +   +       G +    ++ + VA +   +  L
Sbjct: 66  TFEPRKFGPAVVLPSNSFTSGDIVGLYDTNENSQLATGVLTRITQKSVTVAFDESHDLQL 125

Query: 116 RDVRIDLY-----ANDITFRRWLENLNTIKK----AGKRALRFYLGLDEPSQGEEVNFVP 166
              R + Y     AND+T++R  + L T+KK         +   LG   PS   E+  + 
Sbjct: 126 NLDRENTYRLLKLANDVTYKRLKKALMTLKKYHSGPASSLIDILLGSSTPSPAMEIPPLS 185

Query: 167 F-DKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNV 225
           F + +L+ SQ++A+S AL  ++  ++HGP GTGKT T+VE+I Q VK+G KVL  A SN+
Sbjct: 186 FYNTTLDLSQKEAVSFALAQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLCCAPSNI 245

Query: 226 AVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQH---ELYGELRELRVIGQSL 282
           AVDNLVERL+    +I+R+GHP+R+ + +   +L  ++ +    ++  ++R  R I Q  
Sbjct: 246 AVDNLVERLALCKKRILRLGHPARLLESVQHHSLDAVLARSDNAQIVADIR--RDIDQVF 303

Query: 283 AEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDD 342
            + + T  K                   R++G               IKL R+  K  ++
Sbjct: 304 GKNKKTQDK-------------------REKG----------NFRSEIKLLRKELKEREE 334

Query: 343 ARKLEERIARDIIREADVVLTTNSSAA----LEVVDYDTYDVAIIDEATQSTIPSILIPL 398
           A  ++   A      ADVVL TN+ A+    L+++  D +DV ++DE  Q+   S  IPL
Sbjct: 335 AAIVQSLTA------ADVVLATNTGASSDGPLKLLPEDYFDVVVVDECAQALEASCWIPL 388

Query: 399 NKVERFVLAGDHKQLPPTILSLEA--QELSRTLFEGLIERY-PWKSEMLVVQYRMNERIM 455
            K  + +LAGDH+QLPPT +S  A    LSR+L E L E++      ML VQYRM++ IM
Sbjct: 389 LKAPKCILAGDHRQLPPTTVSHRAALAGLSRSLMERLAEKHGAGVVRMLTVQYRMHQAIM 448

Query: 456 EFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWER 515
            + S+  Y G+  +  SV G  L+DL       ++   +L        IDT+      E 
Sbjct: 449 CWASEAMYHGQFTSHPSVAGHLLKDLPGVTDTEETRVPLL-------LIDTAGC-GLLEL 500

Query: 516 QRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDL----ISMKVPEDVE 571
           +   S+S+ NP E  +V   +  L+  GV+   I VI PY+ Q DL    +S K PE +E
Sbjct: 501 EEEDSQSKGNPGEVRLVTLHIQALVDAGVQAGDIAVIAPYNLQVDLLRQSLSNKHPE-LE 559

Query: 572 VKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSH 631
           +K+VDG+QGREKE ++L+ VRSN+ GE+GFL + RR+NV++TRA+R + V+ DS T+++H
Sbjct: 560 IKSVDGFQGREKEAVLLTFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSHTVNNH 619

Query: 632 ETYKKMIEFFKEKG 645
              + ++++F E G
Sbjct: 620 AFLETLVDYFTEHG 633


>pir||T41580 probable dna-binding protein - fission yeast  (Schizosaccharomyces
           pombe) >gi|2370467|emb|CAB11611.1| (Z98951) hypothetical
           protein [Schizosaccharomyces pombe]
           >gi|4239673|emb|CAA20863.1| (AL031546) putative
           dna-binding protein [Schizosaccharomyces pombe]
           Length = 660
           
 Score =  262 bits (662), Expect = 1e-68
 Identities = 208/687 (30%), Positives = 341/687 (49%), Gaps = 88/687 (12%)

Query: 3   ITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYFLV- 61
           I  F +R  E V+  +++E++     ++R      +R G A++NL   ++    G   + 
Sbjct: 15  IQKFGDREIEFVDEAQKSEVDETEKSIKRFPLSVLQRKGLALINLRIGVVKTGFGGKTII 74

Query: 62  ------KYGRNREIKTE-ISVGDLVVI-------SKRDPLKSDLL--GTVVEKGKRFIVV 105
                  +    E+     S GD+V I        K+ P ++D+   G V    +R I V
Sbjct: 75  DFEKDPAFSNGEELPANSFSPGDVVSIRQDFQSSKKKRPNETDISVEGVVTRVHERHISV 134

Query: 106 AL---ETVPEWALRDVRIDLYANDITFRRWLENLNTIKKA--GKRALRFY---------L 151
           AL   E +P    R   + L  N +T+ R    +   K++    R   FY         +
Sbjct: 135 ALKSEEDIPSSVTRLSVVKL-VNRVTYERMRHTMLEFKRSIPEYRNSLFYTLIGRKKADV 193

Query: 152 GLDEPSQGEEVNFVPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEV 211
            +D+   G+      F+K LN SQ+KA+  ++  ++  L+HGP GTGKT TLVE+I+Q V
Sbjct: 194 SIDQKLIGD---IKYFNKELNASQKKAVKFSIAVKELSLIHGPPGTGKTHTLVEIIQQLV 250

Query: 212 KRGNKVLATAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGE 271
            R  ++L    SN+AVDN+V+RLS SGI +VR+GHP+R+   + + +L  L         
Sbjct: 251 LRNKRILVCGASNLAVDNIVDRLSSSGIPMVRLGHPARLLPSILDHSLDVL--------- 301

Query: 272 LRELRVIGQSLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIK 331
                           + T       RG+S++  + L++  +   G   R         +
Sbjct: 302 ----------------SRTGDNGDVIRGISEDIDVCLSKITKTKNGRERR---------E 336

Query: 332 LNRQVQKAFDDARKLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTI 391
           + + +++   D RK E +   +I+  + VV  T   A    +    +D  IIDEA+Q+  
Sbjct: 337 IYKNIRELRKDYRKYEAKTVANIVSASKVVFCTLHGAGSRQLKGQRFDAVIIDEASQALE 396

Query: 392 PSILIPLNKVERFVLAGDHKQLPPTILSLEAQELSRTLFEGLIE-RYPWKSEMLVVQYRM 450
           P   IPL  + + +LAGDH QL P +   +++    ++FE L++ +       L +QYRM
Sbjct: 397 PQCWIPLLGMNKVILAGDHMQLSPNV---QSKRPYISMFERLVKSQGDLVKCFLNIQYRM 453

Query: 451 NERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDT---- 506
           +E I +FPS  FY  K++  E V+   L DL   +    +       ++ I F DT    
Sbjct: 454 HELISKFPSDTFYDSKLVPAEEVKKRLLMDLENVEETELT-------DSPIYFYDTLGNY 506

Query: 507 SKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKV 566
            + +   + Q    +S+ N  EA+IV+  +  LL  G++ + I V+TPY+ Q  LI   +
Sbjct: 507 QEDDRSEDMQNFYQDSKSNHWEAQIVSYHISGLLEAGLEAKDIAVVTPYNAQVALIRQLL 566

Query: 567 PE---DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVG 623
            E   +VE+ +VD  QGREKE II SLVRSN + E+GFL + RRLNV++TR KR L V+G
Sbjct: 567 KEKGIEVEMGSVDKVQGREKEAIIFSLVRSNDVREVGFLAEKRRLNVAITRPKRHLCVIG 626

Query: 624 DSSTLS-SHETYKKMIEFFKEKGCFIE 649
           DS+T+  + E + + ++F +E    ++
Sbjct: 627 DSNTVKWASEFFHQWVDFLEENAIVMD 653


>gi|6322835 DNA helicase A; Hcs1p [Saccharomyces cerevisiae]
           >gi|465704|sp|P34243|YKB7_YEAST HYPOTHETICAL 78.3 KD
           PROTEIN IN RAM2-ATP7 INTERGENIC REGION
           >gi|422147|pir||S34700 probable purine
           nucleotide-binding protein YKL017c - yeast
           (Saccharomyces cerevisiae) >gi|395256|emb|CAA52266.1|
           (X74152) orf4; homologous to human putative GTP-binding
           protein [Saccharomyces cerevisiae]
           >gi|486007|emb|CAA81852.1| (Z28017) ORF YKL017c
           [Saccharomyces cerevisiae]
           Length = 683
           
 Score =  230 bits (581), Expect = 3e-59
 Identities = 216/708 (30%), Positives = 349/708 (48%), Gaps = 113/708 (15%)

Query: 14  VEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEEL-GYFLVKYGRNREI--- 69
           ++ ERE +I+     +  LS  +  + G AI N++ + I   L G   ++ G N  +   
Sbjct: 13  IKHEREQDIQTTSRLLTTLSIQQLVQNGLAINNIHLENIRSGLIGKLYMELGPNLAVNDK 72

Query: 70  --KTEISVGDLVVI--------SKRDPL-----------KSDLLGTVVEKGKRFIVVALE 108
             + +I VGD+V++        +K  P            +++  G V +     I +ALE
Sbjct: 73  IQRGDIKVGDIVLVRPAKTKVNTKTKPKVKKVSEDSNGEQAECSGVVYKMSDTQITIALE 132

Query: 109 TVPE------WALRDVRIDLYANDITFRRW---LENLNTIKKAGKRALRFYLGLDEP--- 156
              +      ++   + I    N +T+ R    +  L+ I    +  +  YL  + P   
Sbjct: 133 ESQDVIATTFYSYSKLYILKTTNVVTYNRMESTMRKLSEISSPIQDKIIQYLVNERPFIP 192

Query: 157 SQGEEVNFVPF-DKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRG- 214
           +     N   F + +LN SQ+ AI+ A+ + D  ++HGP GTGKT TL+ELI+Q + +  
Sbjct: 193 NTNSFQNIKSFLNPNLNDSQKTAINFAINN-DLTIIHGPPGTGKTFTLIELIQQLLIKNP 251

Query: 215 -NKVLATAESNVAVDNLVERLSR--SGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGE 271
             ++L    SN++VD ++ERL+       ++RIGHP+R+       +L  L         
Sbjct: 252 EERILICGPSNISVDTILERLTPLVPNNLLLRIGHPARLLDSNKRHSLDIL--------- 302

Query: 272 LRELRVIGQSLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIK 331
                        K++T  K           +EI KL +  +  +    R   E    IK
Sbjct: 303 ------------SKKNTIVKDI--------SQEIDKLIQENKKLKNYKQR--KENWNEIK 340

Query: 332 LNRQVQKAFDDARKLEERIARDIIREADVVLTT-NSSAALEVV-------DYDTYDVAII 383
           L R+      D +K E +  +D+I ++ +V+TT + S++ E+        ++  +D  II
Sbjct: 341 LLRK------DLKKREFKTIKDLIIQSRIVVTTLHGSSSRELCSLYRDDPNFQLFDTLII 394

Query: 384 DEATQSTIPSILIPL----NKVERFVLAGDHKQLPPTILSLEAQE----LSRTLFEGLIE 435
           DE +Q+  P   IPL    N+  + VLAGD+KQLPPTI + + +     L  TLF+ +I+
Sbjct: 395 DEVSQAMEPQCWIPLIAHQNQFHKLVLAGDNKQLPPTIKTEDDKNVIHNLETTLFDRIIK 454

Query: 436 RYPWKS--EMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQ---SPNDS 490
            +P +   + L VQYRMN++IMEFPS   Y GK++AD +V    L DL       S +D 
Sbjct: 455 IFPKRDMVKFLNVQYRMNQKIMEFPSHSMYNGKLLADATVANRLLIDLPTVDATPSEDDD 514

Query: 491 WGKILNPENVIVFIDTSKAE-NKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWI 549
             KI      +++ DT   E  +   +     S+ N  E  IV + ++ L S  V    I
Sbjct: 515 DTKI-----PLIWYDTQGDEFQETADEATILGSKYNEGEIAIVKEHIENLRSFNVPENSI 569

Query: 550 GVITPYDDQRDLISMKVPE-----DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKD 604
           GVI+PY+ Q   +   + +     D+E+ TVDG+QGREK+VIILSLVRSN+  E+GFLK+
Sbjct: 570 GVISPYNAQVSHLKKLIHDELKLTDIEISTVDGFQGREKDVIILSLVRSNEKFEVGFLKE 629

Query: 605 LRRLNVSLTRAKRKLIVVGDSSTLS-SHETYKKMIEFFKEKGCFIEFP 651
            RRLNV++TR +R+L+VVG+   L      Y K    + E+   + +P
Sbjct: 630 ERRLNVAMTRPRRQLVVVGNIEVLQRCGNKYLKSWSEWCEENADVRYP 677


>dbj|BAB09253.1| (AB026643) DNA helicase-like [Arabidopsis thaliana]
           Length = 750
           
 Score =  219 bits (553), Expect = 6e-56
 Identities = 213/703 (30%), Positives = 332/703 (46%), Gaps = 113/703 (16%)

Query: 3   ITSFINRLKELVEIEREAEIEAMRLEMRRLS------------------GIERERLGRAI 44
           I  F +++ +L+++ER+ E+E  + E+  +                   G   + L   I
Sbjct: 53  IDEFTSQMSQLLQVERDTELEVTQEELDVVPTPDESSDSSKPIEFLVRHGDAPQELCDTI 112

Query: 45  LNLNGKIIGEELG---YFLVKYGRNREIK-TEISVGDLVVISKRDPLKSDLL----GTVV 96
            NL        LG     L K G N  +  T +S GD+V I   D   +       G V 
Sbjct: 113 CNLYAVSTSTGLGGMHLVLFKVGGNHRLPPTTLSPGDMVCIRVCDSRGAGATACTQGFVH 172

Query: 97  EKGKR--FIVVALE------TVPEWALRDVRIDLY---ANDITFRRWLENLNTIKKAGKR 145
             G+    I VALE      T  +   + VRID     A+ +T+ R  E L  ++K G +
Sbjct: 173 NLGEDGCSIGVALESRHGDPTFSKLFGKSVRIDRIHGLADALTYERNCEALMLLQKNGLQ 232

Query: 146 ALRFYLGLDEP--SQGEEVNFV----------------PFDKSLNRSQRKAISKALGSE- 186
                + +       GE++ ++                P  K  + SQR+AI+  +  + 
Sbjct: 233 KKNPSISVVATLFGDGEDITWLEQNDYVDWSEAELSDEPVSKLFDSSQRRAIALGVNKKR 292

Query: 187 DFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLSRSGIKIVRIGH 246
              +V GP GTGKT  L E+I   V++G +VL TA +N AVDN+VE+L   G+ IVR+G+
Sbjct: 293 PVMIVQGPPGTGKTGMLKEVITLAVQQGERVLVTAPTNAAVDNMVEKLLHLGLNIVRVGN 352

Query: 247 PSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGLSDEEII 306
           P+R+S  +   +L  ++          +L      L  K+    K     R+ L D+ + 
Sbjct: 353 PARISSAVASKSLGEIVNS--------KLASFRAELERKKSDLRK---DLRQCLRDDVL- 400

Query: 307 KLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREADVVLTTNS 366
                   A G+  +L+ ++ + +K             K E+   ++I+  A VV  TN 
Sbjct: 401 --------AAGI-RQLLKQLGKTLK-------------KKEKETVKEILSNAQVVFATNI 438

Query: 367 SAALEVV-DYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSLEAQE- 424
            AA  ++   +T+D+ +IDEA QS  PS  IP+ + +R +L+GD  QL P +LS +A E 
Sbjct: 439 GAADPLIRRLETFDLVVIDEAGQSIEPSCWIPILQGKRCILSGDPCQLAPVVLSRKALEG 498

Query: 425 -LSRTLFEGLIERYPW-KSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLV 482
            L  +L E     +    +  L  QYRMN+ I  + SKE YGG +   +S   +    L+
Sbjct: 499 GLGVSLLERAASLHDGVLATKLTTQYRMNDVIAGWASKEMYGGWL---KSAPSVASHLLI 555

Query: 483 EYQSPNDSWGKILNPENVIVFIDT-----SKAENKWER-QRRGSESRENPLEAEIVAKIV 536
           +      +W      +  +V +DT     S +    ER    G+ S  N  EA+IV   V
Sbjct: 556 DSPFVKATW----ITQCPLVLLDTRMPYGSLSVGCEERLDPAGTGSLYNEGEADIVVNHV 611

Query: 537 DKLLSIGVKPEWIGVITPYDDQRDLI-----SMKVPEDVEVKTVDGYQGREKEVIILSLV 591
             L+  GV P  I V +PY  Q  L+        V + VEV T+D +QGRE + +I+S+V
Sbjct: 612 ISLIYAGVSPMAIAVQSPYVAQVQLLRERLDDFPVADGVEVATIDSFQGREADAVIISMV 671

Query: 592 RSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETY 634
           RSN LG +GFL D RR+NV++TRA++ + VV DSST+  H T+
Sbjct: 672 RSNNLGAVGFLGDSRRMNVAITRARKHVAVVCDSSTI-CHNTF 713


>pir||D72258 helicase-related protein - Thermotoga maritima (strain MSB8)
           >gi|4981975|gb|AAD36482.1|AE001793_12 (AE001793)
           helicase-related protein [Thermotoga maritima]
           Length = 245
           
 Score =  215 bits (543), Expect = 9e-55
 Identities = 104/157 (66%), Positives = 131/157 (83%)

Query: 494 ILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVIT 553
           +L+P+NV+VFIDT    +++ERQR+ S SRENPLEA+IV ++V+KLLS+GVK +WIG+IT
Sbjct: 89  VLSPKNVLVFIDTKNRSDRFERQRKDSPSRENPLEAQIVKEVVEKLLSMGVKEDWIGIIT 148

Query: 554 PYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLT 613
           PYDDQ +LI   +   VEV +VDG+QGREKEVII+S VRSNK GEIGFL+DLRRLNVSLT
Sbjct: 149 PYDDQVNLIRELIEAKVEVHSVDGFQGREKEVIIISFVRSNKNGEIGFLEDLRRLNVSLT 208

Query: 614 RAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGCFIEF 650
           RAKRKLI  GDSSTLS H TY++ +EF K+KG ++ F
Sbjct: 209 RAKRKLIATGDSSTLSVHPTYRRFVEFVKKKGTYVIF 245


>emb|CAC18314.1| (AL451022) probable HUPF1 protein [Neurospora crassa]
           Length = 1093
           
 Score =  215 bits (541), Expect = 2e-54
 Identities = 177/507 (34%), Positives = 252/507 (48%), Gaps = 85/507 (16%)

Query: 165 VPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGN-KVLATAES 223
           VP    LN SQ  AI + L S    L+ GP GTGKT T   +I    K  N +VL  A S
Sbjct: 450 VPGLPELNASQIAAIKQVL-SNPLSLIQGPPGTGKTVTSATIIYHLAKMSNSQVLVCAPS 508

Query: 224 NVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLA 283
           NVAVD L ER+ R+G+K+VR+   SR      E+++++L    ++               
Sbjct: 509 NVAVDQLCERIHRTGLKVVRLTAKSREDV---ESSVSFLALHEQV--------------- 550

Query: 284 EKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDA 343
                        R   +++E+  L + K               E  +L+ Q +K F   
Sbjct: 551 -------------RMNTTNKELDGLVKLK--------------TETGELSSQDEKRF--- 580

Query: 344 RKLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNK-VE 402
           ++L  +  R+I++ ADVV  T   A    +    +   +IDE+TQS  P  +IPL    +
Sbjct: 581 KQLTRQAEREILQNADVVCCTCVGAGDPRLSKMKFRNVLIDESTQSAEPECMIPLVLGCK 640

Query: 403 RFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSK 460
           + VL GDHKQL P I++ +A +  L+++LFE L+ +  +    L VQYRM+  + EFPS 
Sbjct: 641 QVVLVGDHKQLGPVIMNKKAAKAGLNQSLFERLV-KLQFTPIRLKVQYRMHPCLSEFPSN 699

Query: 461 EFYGGKIIADESVRGIT----LRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQ 516
            FY G +       G+T    LR  V++  P         PE  ++F   S   N  E  
Sbjct: 700 MFYEGSL-----QNGVTAAERLRKDVDFPWPV--------PETPMMF--WSNLGN--EEI 742

Query: 517 RRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE-------- 568
                S  N  EA  V KIV +    GVKP  IGVITPY+ QR  I   +          
Sbjct: 743 SASGTSYLNRTEAANVEKIVTRFFKAGVKPADIGVITPYEGQRSYIVNTMQNTGTFKKES 802

Query: 569 --DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSS 626
             +VEV +VD +QGREK+ I+LS VRSN+   IGFL D RRLNV+LTRAK  L+++G+  
Sbjct: 803 YREVEVASVDAFQGREKDFIVLSCVRSNENQGIGFLSDPRRLNVALTRAKYGLVIIGNPK 862

Query: 627 TLSSHETYKKMIEFFKEKGCFIEFPFS 653
            L  HE +  ++  FK+K C +E P +
Sbjct: 863 VLCKHELWHHLLVHFKDKKCLVEGPLT 889


>pir||T43280 nonsense-mediated mRNA decay trans-acting factor - Caenorhabditis
           elegans >gi|3328177|gb|AAC26789.1| (AF074017)
           nonsense-mediated mRNA decay trans-acting factor
           [Caenorhabditis elegans]
           Length = 1069
           
 Score =  206 bits (519), Expect = 6e-52
 Identities = 183/561 (32%), Positives = 273/561 (48%), Gaps = 95/561 (16%)

Query: 120 IDLYANDITFRRWLENLNTIKKAGKRALRFYLGLDEPSQGEEVNFVPFD----------K 169
           +D+  N  TF R  + L  +    K A+  YL         E   + FD           
Sbjct: 386 VDVVWNATTFERQYKALAALLNDSK-AISPYLYQKLLGHPAEEMMLKFDLPRRLSVAGLP 444

Query: 170 SLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKR--GNKVLATAESNVAV 227
            LN SQ +A+ + L +    L+ GP GTGKT     ++   V++  GN VL  + SN+AV
Sbjct: 445 ELNSSQMQAVKQVL-TRPLSLIQGPPGTGKTVVSATIVYHLVQKTEGN-VLVCSPSNIAV 502

Query: 228 DNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRD 287
           D+L E++ ++G+K+VR+   SR      ETT+ YL  QH+L       +V+G +      
Sbjct: 503 DHLAEKIHKTGLKVVRLCARSREHS---ETTVPYLTLQHQL-------KVMGGA------ 546

Query: 288 TYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLE 347
                           E+ KL + K  A  L  +                   DD R ++
Sbjct: 547 ----------------ELQKLIQLKDEAGELEFK-------------------DDLRYMQ 571

Query: 348 ERIARD--IIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNK-VERF 404
            +  ++  ++  ADV+  T SSAA   +        +IDE+TQ+T P IL+ + + V + 
Sbjct: 572 LKRVKEHELLAAADVICCTCSSAADARLSKIRTRTVLIDESTQATEPEILVSIMRGVRQL 631

Query: 405 VLAGDHKQLPPTILSLEAQ--ELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEF 462
           VL GDH QL P ++  +A    LS++LFE L+     +   L VQYRM+  + EFPS  F
Sbjct: 632 VLVGDHCQLGPVVICKKAAIAGLSQSLFERLV-LLGIRPFRLQVQYRMHPVLSEFPSNVF 690

Query: 463 YGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSES 522
           Y G +       G+T  D       +  W K   P     F   S +E   E    G+ S
Sbjct: 691 YDGSL-----QNGVTENDR-HMTGVDWHWPK---PNKPAFFWHCSGSE---ELSASGT-S 737

Query: 523 RENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLI----------SMKVPEDVEV 572
             N  EA  V K+V KL+  GV+P  IGVIT Y+ QR  I          + K+ E+VE+
Sbjct: 738 FLNRTEAANVEKLVSKLIKAGVQPHQIGVITSYEGQRSFIVNYMHTQGTLNSKLYENVEI 797

Query: 573 KTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHE 632
            +VD +QGREK+ II++ VRSN +  IGFL D RRLNV++TRAK  L++VG++  L+ H+
Sbjct: 798 ASVDAFQGREKDYIIVTCVRSNDILGIGFLSDPRRLNVAITRAKYGLVLVGNAKVLARHD 857

Query: 633 TYKKMIEFFKEKGCFIEFPFS 653
            + ++I  +K K    E P +
Sbjct: 858 LWHELINHYKSKEMLYEGPIN 878


>gi|6323726 putative helicase; Nam7p [Saccharomyces cerevisiae]
           >gi|400350|sp|P30771|NAM7_YEAST NAM7 PROTEIN
           (NONSENSE-MEDIATED MRNA DECAY PROTEIN 1) (UP-FRAMESHIFT
           SUPPRESSOR 1) >gi|83347|pir||S23408 prematurely
           terminated mRNA decay factor NAM7 - yeast
           (Saccharomyces cerevisiae) >gi|4023|emb|CAA44266.1|
           (X62394) helicase [Saccharomyces cerevisiae]
           >gi|173142|gb|AAA35197.1| (M76659) zinc finger protein
           [Saccharomyces cerevisiae] >gi|807962|emb|CAA89226.1|
           (Z49259) Nam7p [Saccharomyces cerevisiae]
           Length = 971
           
 Score =  202 bits (508), Expect = 1e-50
 Identities = 167/501 (33%), Positives = 242/501 (47%), Gaps = 83/501 (16%)

Query: 165 VPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVK-RGNKVLATAES 223
           +P    LN SQ  A+S  L      L+ GP GTGKT T   ++    K   +++L  A S
Sbjct: 403 IPNFAQLNSSQSNAVSHVL-QRPLSLIQGPPGTGKTVTSATIVYHLSKIHKDRILVCAPS 461

Query: 224 NVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLA 283
           NVAVD+L  +L   G+K+VR+   SR       + LA     H L G             
Sbjct: 462 NVAVDHLAAKLRDLGLKVVRLTAKSREDVESSVSNLAL----HNLVG------------- 504

Query: 284 EKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDA 343
                                        RGA+G    L+    E  +L+    K F   
Sbjct: 505 -----------------------------RGAKGELKNLLKLKDEVGELSASDTKRFV-- 533

Query: 344 RKLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNK-VE 402
            KL  +   +I+ +ADVV  T   A  + +D   +   +IDE+TQ++ P  LIP+ K  +
Sbjct: 534 -KLVRKTEAEILNKADVVCCTCVGAGDKRLD-TKFRTVLIDESTQASEPECLIPIVKGAK 591

Query: 403 RFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIE--RYPWKSEMLVVQYRMNERIMEFP 458
           + +L GDH+QL P IL  +A +  L ++LFE LI     P + E   VQYRMN  + EFP
Sbjct: 592 QVILVGDHQQLGPVILERKAADAGLKQSLFERLISLGHVPIRLE---VQYRMNPYLSEFP 648

Query: 459 SKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRR 518
           S  FY G +       G+T+    +   PN  +   +    ++ + +  + E        
Sbjct: 649 SNMFYEGSL-----QNGVTIE---QRTVPNSKFPWPIRGIPMMFWANYGREEIS-----A 695

Query: 519 GSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPED--------- 569
              S  N +EA    +I+ KL   GVKPE IGVITPY+ QR  I   +  +         
Sbjct: 696 NGTSFLNRIEAMNCERIITKLFRDGVKPEQIGVITPYEGQRAYILQYMQMNGSLDKDLYI 755

Query: 570 -VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL 628
            VEV +VD +QGREK+ IILS VR+N+   IGFL+D RRLNV LTRAK  L+++G+  +L
Sbjct: 756 KVEVASVDAFQGREKDYIILSCVRANEQQAIGFLRDPRRLNVGLTRAKYGLVILGNPRSL 815

Query: 629 SSHETYKKMIEFFKEKGCFIE 649
           + +  +  ++  F+EKGC +E
Sbjct: 816 ARNTLWNHLLIHFREKGCLVE 836


>dbj|BAB10240.1| (AB013394) prematurely terminated mRNA decay factor-like protein
           [Arabidopsis thaliana]
           Length = 1235
           
 Score =  200 bits (504), Expect = 3e-50
 Identities = 167/505 (33%), Positives = 245/505 (48%), Gaps = 79/505 (15%)

Query: 165 VPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGN-KVLATAES 223
           VP    LN SQ  A+   L  +   L+ GP GTGKT T   ++    K+G  +VL  A S
Sbjct: 480 VPGLPELNASQVNAVKSVL-QKPISLIQGPPGTGKTVTSAAIVYHMAKQGQGQVLVCAPS 538

Query: 224 NVAVDNLVERLSRSGIKIVRIGHPSR--VSKHLHETTLAYLITQHELYGELRELRVIGQS 281
           NVAVD L E++S +G+K+VR+   SR  VS  +   TL Y + +H    E  EL  + Q 
Sbjct: 539 NVAVDQLAEKISATGLKVVRLCAKSREAVSSPVEYLTLHYQV-RHLDTSEKSELHKLQQ- 596

Query: 282 LAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFD 341
                             L DE+                          +L+   +K + 
Sbjct: 597 ------------------LKDEQG-------------------------ELSSSDEKKYK 613

Query: 342 DARKLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNK- 400
           + ++  ER   +I + ADV+  T   AA   +    +   +IDE+TQ+T P  LIPL   
Sbjct: 614 NLKRATER---EITQSADVICCTCVGAADLRLSNFRFRQVLIDESTQATEPECLIPLVLG 670

Query: 401 VERFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFP 458
           V++ VL GDH QL P I+  +A    L+++LFE L+     K   L VQYRM+  + EFP
Sbjct: 671 VKQVVLVGDHCQLGPVIMCKKAARAGLAQSLFERLVT-LGIKPIRLQVQYRMHPALSEFP 729

Query: 459 SKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRR 518
           S  FY G +       G+T+   +E Q+    +   +    +  ++   + E        
Sbjct: 730 SNSFYEGTL-----QNGVTI---IERQTTGIDFPWPVPNRPMFFYVQLGQEEIS-----A 776

Query: 519 GSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLI----------SMKVPE 568
              S  N  EA  V K+V   L  GV P  IGVITPY+ QR  I            ++ +
Sbjct: 777 SGTSYLNRTEAANVEKLVTAFLKSGVVPSQIGVITPYEGQRAYIVNYMARNGSLRQQLYK 836

Query: 569 DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL 628
           ++EV +VD +QGREK+ IILS VRSN+   IGFL D RRLNV+LTRA+  ++++G+   L
Sbjct: 837 EIEVASVDSFQGREKDYIILSCVRSNEHQGIGFLNDPRRLNVALTRARYGIVILGNPKVL 896

Query: 629 SSHETYKKMIEFFKEKGCFIEFPFS 653
           S    +  ++  +KE  C +E P +
Sbjct: 897 SKQPLWNGLLTHYKEHECLVEGPLN 921


>pir||T40065 tRNA-splicing endonuclease positive effector - fission yeast
            (Schizosaccharomyces pombe) >gi|4007798|emb|CAA22438.1|
            (AL034463) tRNA-splicing endonuclease positive effector
            [Schizosaccharomyces pombe]
            Length = 1944
            
 Score =  197 bits (496), Expect = 3e-49
 Identities = 158/530 (29%), Positives = 258/530 (47%), Gaps = 80/530 (15%)

Query: 171  LNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRG---------------- 214
            +N  Q  AI  +  ++ F L+ GP GTGKT+T++ +I   +                   
Sbjct: 1271 VNEPQAYAIYASSVNDGFTLIQGPPGTGKTKTILGMIGAVLTSSSQGLQFNVPGQTRKTS 1330

Query: 215  -NKVLATAESNVAVDNLVERLS-----RSGIK----IVRIGHPSRVSKHLHETTLA-YLI 263
             NK+L  A SN A+D ++ R+        GIK    ++R+G    +S H  E TL   +I
Sbjct: 1331 KNKILICAPSNAAIDEILLRIKAGVYDHEGIKFFPKVIRVGFGDSISVHAKEFTLEEQMI 1390

Query: 264  TQHELYGELRELRVIGQSLAEKR-DTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARL 322
             Q EL    ++      S   K+ D+  K     R  L         E+ R     S+ L
Sbjct: 1391 KQMELTNLKKDQEANNSSDTRKKYDSIIKKRDSLREDL---------EKFRSTGKNSSIL 1441

Query: 323  IMEMAEWIKLNRQVQKAFDDARK-----------LEERIARDIIREADVVLTTNSSAALE 371
              ++ E  K    ++++ DD R+           L+++I   +++EAD+V  T S++  E
Sbjct: 1442 EAQLREITKQKNMLEQSLDDMRERQRSTNRNLDVLKKQIQNQLLQEADIVCATLSASGHE 1501

Query: 372  VVDYD--TYDVAIIDEATQSTIPSILIPLNK-VERFVLAGDHKQLPPTILSLEAQEL--S 426
            ++     T+   IIDEA Q+   S +IPL    E  V+ GD  QLPPT+LS  + +   S
Sbjct: 1502 LLLNAGLTFRTVIIDEAAQAVELSSIIPLKYGCESCVMVGDPNQLPPTVLSKTSAKFGYS 1561

Query: 427  RTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQS 486
            ++L+  + +++   + +L +QYRMN  I  FPSK FY  K++   ++  +T R    ++ 
Sbjct: 1562 QSLYVRMFKQHNESACLLSIQYRMNPEISRFPSKFFYNSKLLDGPNMSAVTSRPW--HED 1619

Query: 487  PNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKP 546
            P     +  N      F +              S+S  N  EA  +  + ++L+   +  
Sbjct: 1620 PQLGIYRFFNVHGTEAFSN--------------SKSLYNVEEASFILLLYERLIQCYLNI 1665

Query: 547  EW---IGVITPYDDQRDLISMK--------VPEDVEVKTVDGYQGREKEVIILSLVRSNK 595
            ++   IGV+TPY  Q   +  +        + + +++ TVDG+QG+EK++II S VRS+ 
Sbjct: 1666 DFEGKIGVVTPYRSQVQQLRSQFQRKYGSIIFKHLDIHTVDGFQGQEKDIIIFSCVRSSM 1725

Query: 596  LGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKG 645
             G IGFL+DLRRLNV+LTRAK  L +VG+S  L   + +  +IE  K +G
Sbjct: 1726 SGGIGFLQDLRRLNVALTRAKSSLYIVGNSKPLMQEDIFYSLIEDAKTRG 1775


>gb|AAB94785.1| (AC003972) pNORF1 [Homo sapiens] >gi|3328175|gb|AAC26788.1|
           (AF074016) nonsense-mediated mRNA decay trans-acting
           factor [Homo sapiens]
           Length = 1118
           
 Score =  192 bits (484), Expect = 7e-48
 Identities = 159/497 (31%), Positives = 246/497 (48%), Gaps = 77/497 (15%)

Query: 171 LNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGN-KVLATAESNVAVDN 229
           LN SQ  A+   L      L+ GP GTGKT T   ++    ++GN  VL  A SN+AVD 
Sbjct: 471 LNHSQVYAVKTVL-QRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQ 529

Query: 230 LVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTY 289
           L E++ ++G+K+VR+   SR +     + LA       L+ ++R +              
Sbjct: 530 LTEKIHQTGLKVVRLCAKSREAIDSPVSFLA-------LHNQIRNMD------------- 569

Query: 290 TKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEER 349
                      S  E+ KL + K               E  +L+   +K +   R L+  
Sbjct: 570 -----------SMPELQKLQQLKD--------------ETGELSSADEKRY---RALKRT 601

Query: 350 IARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNK-VERFVLAG 408
             R+++  ADV+  T   A    +    +   +IDE+TQ+T P  ++P+    ++ +L G
Sbjct: 602 AERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVG 661

Query: 409 DHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGK 466
           DH QL P ++  +A +  LS++LFE L+     +   L VQYRM+  +  FPS  FY G 
Sbjct: 662 DHCQLGPVVMCKKAAKAGLSQSLFERLVV-LGIRPIRLQVQYRMHPALSAFPSNIFYEGS 720

Query: 467 IIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENP 526
           +       G+T  D V+ +  +  W +   P+  + F  T   E   E    G+ S  N 
Sbjct: 721 L-----QNGVTAADRVK-KGFDFQWPQ---PDKPMFFYVTQGQE---EIASSGT-SYLNR 767

Query: 527 LEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISM----------KVPEDVEVKTVD 576
            EA  V KI  KLL  G KP+ IG+ITPY+ QR  +            K+ ++VE+ +VD
Sbjct: 768 TEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVD 827

Query: 577 GYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKK 636
            +QGREK+ IILS VR+N+   IGFL D RRLNV+LTRA+  +I+VG+   LS    +  
Sbjct: 828 AFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNH 887

Query: 637 MIEFFKEKGCFIEFPFS 653
           ++ ++KE+   +E P +
Sbjct: 888 LLNYYKEQKVLVEGPLN 904


>gb|AAC51140.1| (U59323) type 1 RNA helicase pNORF1 [Homo sapiens]
           Length = 1118
           
 Score =  192 bits (484), Expect = 7e-48
 Identities = 159/497 (31%), Positives = 246/497 (48%), Gaps = 77/497 (15%)

Query: 171 LNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGN-KVLATAESNVAVDN 229
           LN SQ  A+   L      L+ GP GTGKT T   ++    ++GN  VL  A SN+AVD 
Sbjct: 471 LNHSQVYAVKTVL-QRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQ 529

Query: 230 LVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTY 289
           L E++ ++G+K+VR+   SR +     + LA       L+ ++R +              
Sbjct: 530 LTEKIHQTGLKVVRLCAKSREAIDSPVSFLA-------LHNQIRNMD------------- 569

Query: 290 TKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEER 349
                      S  E+ KL + K               E  +L+   +K +   R L+  
Sbjct: 570 -----------SMPELQKLQQLKD--------------ETGELSSADEKRY---RALKRT 601

Query: 350 IARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNK-VERFVLAG 408
             R+++  ADV+  T   A    +    +   +IDE+TQ+T P  ++P+    ++ +L G
Sbjct: 602 AERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVG 661

Query: 409 DHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGK 466
           DH QL P ++  +A +  LS++LFE L+     +   L VQYRM+  +  FPS  FY G 
Sbjct: 662 DHCQLGPVVMCKKAAKAGLSQSLFERLVV-LGIRPIRLQVQYRMHPALSAFPSNIFYEGS 720

Query: 467 IIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENP 526
           +       G+T  D V+ +  +  W +   P+  + F  T   E   E    G+ S  N 
Sbjct: 721 L-----QNGVTAADRVK-KGFDFQWPQ---PDKPMFFYVTQGQE---EIASSGT-SYLNR 767

Query: 527 LEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISM----------KVPEDVEVKTVD 576
            EA  V KI  KLL  G KP+ IG+ITPY+ QR  +            K+ ++VE+ +VD
Sbjct: 768 TEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVD 827

Query: 577 GYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKK 636
            +QGREK+ IILS VR+N+   IGFL D RRLNV+LTRA+  +I+VG+   LS    +  
Sbjct: 828 AFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNH 887

Query: 637 MIEFFKEKGCFIEFPFS 653
           ++ ++KE+   +E P +
Sbjct: 888 LLNYYKEQKVLVEGPLN 904


>dbj|BAA19664.1| (D86988) KIAA0221 [Homo sapiens]
           Length = 1129
           
 Score =  192 bits (484), Expect = 7e-48
 Identities = 159/497 (31%), Positives = 246/497 (48%), Gaps = 77/497 (15%)

Query: 171 LNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGN-KVLATAESNVAVDN 229
           LN SQ  A+   L      L+ GP GTGKT T   ++    ++GN  VL  A SN+AVD 
Sbjct: 482 LNHSQVYAVKTVL-QRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQ 540

Query: 230 LVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTY 289
           L E++ ++G+K+VR+   SR +     + LA       L+ ++R +              
Sbjct: 541 LTEKIHQTGLKVVRLCAKSREAIDSPVSFLA-------LHNQIRNMD------------- 580

Query: 290 TKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEER 349
                      S  E+ KL + K               E  +L+   +K +   R L+  
Sbjct: 581 -----------SMPELQKLQQLKD--------------ETGELSSADEKRY---RALKRT 612

Query: 350 IARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNK-VERFVLAG 408
             R+++  ADV+  T   A    +    +   +IDE+TQ+T P  ++P+    ++ +L G
Sbjct: 613 AERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVG 672

Query: 409 DHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGK 466
           DH QL P ++  +A +  LS++LFE L+     +   L VQYRM+  +  FPS  FY G 
Sbjct: 673 DHCQLGPVVMCKKAAKAGLSQSLFERLVV-LGIRPIRLQVQYRMHPALSAFPSNIFYEGS 731

Query: 467 IIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENP 526
           +       G+T  D V+ +  +  W +   P+  + F  T   E   E    G+ S  N 
Sbjct: 732 L-----QNGVTAADRVK-KGFDFQWPQ---PDKPMFFYVTQGQE---EIASSGT-SYLNR 778

Query: 527 LEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISM----------KVPEDVEVKTVD 576
            EA  V KI  KLL  G KP+ IG+ITPY+ QR  +            K+ ++VE+ +VD
Sbjct: 779 TEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVD 838

Query: 577 GYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKK 636
            +QGREK+ IILS VR+N+   IGFL D RRLNV+LTRA+  +I+VG+   LS    +  
Sbjct: 839 AFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNH 898

Query: 637 MIEFFKEKGCFIEFPFS 653
           ++ ++KE+   +E P +
Sbjct: 899 LLNYYKEQKVLVEGPLN 915


>sp|Q09820|YAC6_SCHPO HYPOTHETICAL 105.6 KD PROTEIN C16C9.06C IN CHROMOSOME I
           >gi|2130283|pir||S62476 hypothetical protein
           SPAC16C9.06c - fission yeast  (Schizosaccharomyces
           pombe)
           Length = 935
           
 Score =  191 bits (480), Expect = 2e-47
 Identities = 164/510 (32%), Positives = 251/510 (49%), Gaps = 93/510 (18%)

Query: 165 VPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELI-------RQEVKRGNKV 217
           VP    LN SQ +A+ +A+ S+   L+ GP GTGKT T   ++        ++ K  + V
Sbjct: 397 VPNLPKLNASQSEAV-RAVLSKPLSLIQGPPGTGKTVTSASVVYHLATMQSRKRKSHSPV 455

Query: 218 LATAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRV 277
           L  A SNVAVD L E++ R+G+++VR+   SR      E+++++L               
Sbjct: 456 LVCAPSNVAVDQLAEKIHRTGLRVVRVAAKSREDI---ESSVSFL--------------- 497

Query: 278 IGQSLAEKRDTYTKPTPKFRRGL---SDEEIIKLAERKRGARGLSARLIMEMAEWIKLNR 334
              SL E+   Y K  P+ +R L   S+   + + + K+       R+++  AE      
Sbjct: 498 ---SLHEQIKNY-KFNPELQRLLKLRSENNELSIQDEKK------LRILVAAAE------ 541

Query: 335 QVQKAFDDARKLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSI 394
                            ++++R A V+  T   A    +    +   +IDEATQ++ P  
Sbjct: 542 -----------------KELLRAAHVICCTCVGAGDRRISKYKFRSVLIDEATQASEPEC 584

Query: 395 LIPLNK-VERFVLAGDHKQLPPTILSLEAQ--ELSRTLFEGLI--ERYPWKSEMLVVQYR 449
           +IPL    ++ VL GDH+QL P +++ +     LS++LFE LI     P++   LVVQYR
Sbjct: 585 MIPLVLGAKQVVLVGDHQQLGPVVMNKKVALASLSQSLFERLIILGNSPFR---LVVQYR 641

Query: 450 MNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKA 509
           M+  + EFPS  FY G +       G+T  + +  +  +  W   + P++ ++F     A
Sbjct: 642 MHPCLSEFPSNTFYEGTL-----QNGVTTSERIA-RHVDFPW---IQPDSPLMFY----A 688

Query: 510 ENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPED 569
               E       S  N  EA    KIV   L   V PE IG++TPYD QR  I   +  +
Sbjct: 689 NFGQEELSASGTSFLNRTEASTCEKIVTTFLRSNVLPEQIGIVTPYDGQRSYIVQYMQNN 748

Query: 570 ----------VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKL 619
                     VEV +VD +QGREK+ IILS VRS++   IGF+ D RRLNV+LTRAK  +
Sbjct: 749 GSMQKDLYKAVEVASVDAFQGREKDFIILSCVRSSEHQGIGFVNDPRRLNVALTRAKYGV 808

Query: 620 IVVGDSSTLSSHETYKKMIEFFKEKGCFIE 649
           IV+G+   L+ H  +   +   KEKG  +E
Sbjct: 809 IVLGNPKVLAKHALWYHFVLHCKEKGYLVE 838


>pir||T37779 probable regulator of nonsense transcript stability - fission yeast
           (Schizosaccharomyces pombe) >gi|4894186|emb|CAA91194.2|
           (Z54366) putative regulator of nonsense transcript
           stability [Schizosaccharomyces pombe]
           Length = 925
           
 Score =  191 bits (480), Expect = 2e-47
 Identities = 164/510 (32%), Positives = 251/510 (49%), Gaps = 93/510 (18%)

Query: 165 VPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELI-------RQEVKRGNKV 217
           VP    LN SQ +A+ +A+ S+   L+ GP GTGKT T   ++        ++ K  + V
Sbjct: 387 VPNLPKLNASQSEAV-RAVLSKPLSLIQGPPGTGKTVTSASVVYHLATMQSRKRKSHSPV 445

Query: 218 LATAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRV 277
           L  A SNVAVD L E++ R+G+++VR+   SR      E+++++L               
Sbjct: 446 LVCAPSNVAVDQLAEKIHRTGLRVVRVAAKSREDI---ESSVSFL--------------- 487

Query: 278 IGQSLAEKRDTYTKPTPKFRRGL---SDEEIIKLAERKRGARGLSARLIMEMAEWIKLNR 334
              SL E+   Y K  P+ +R L   S+   + + + K+       R+++  AE      
Sbjct: 488 ---SLHEQIKNY-KFNPELQRLLKLRSENNELSIQDEKK------LRILVAAAE------ 531

Query: 335 QVQKAFDDARKLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSI 394
                            ++++R A V+  T   A    +    +   +IDEATQ++ P  
Sbjct: 532 -----------------KELLRAAHVICCTCVGAGDRRISKYKFRSVLIDEATQASEPEC 574

Query: 395 LIPLNK-VERFVLAGDHKQLPPTILSLEAQ--ELSRTLFEGLI--ERYPWKSEMLVVQYR 449
           +IPL    ++ VL GDH+QL P +++ +     LS++LFE LI     P++   LVVQYR
Sbjct: 575 MIPLVLGAKQVVLVGDHQQLGPVVMNKKVALASLSQSLFERLIILGNSPFR---LVVQYR 631

Query: 450 MNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKA 509
           M+  + EFPS  FY G +       G+T  + +  +  +  W   + P++ ++F     A
Sbjct: 632 MHPCLSEFPSNTFYEGTL-----QNGVTTSERIA-RHVDFPW---IQPDSPLMFY----A 678

Query: 510 ENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPED 569
               E       S  N  EA    KIV   L   V PE IG++TPYD QR  I   +  +
Sbjct: 679 NFGQEELSASGTSFLNRTEASTCEKIVTTFLRSNVLPEQIGIVTPYDGQRSYIVQYMQNN 738

Query: 570 ----------VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKL 619
                     VEV +VD +QGREK+ IILS VRS++   IGF+ D RRLNV+LTRAK  +
Sbjct: 739 GSMQKDLYKAVEVASVDAFQGREKDFIILSCVRSSEHQGIGFVNDPRRLNVALTRAKYGV 798

Query: 620 IVVGDSSTLSSHETYKKMIEFFKEKGCFIE 649
           IV+G+   L+ H  +   +   KEKG  +E
Sbjct: 799 IVLGNPKVLAKHALWYHFVLHCKEKGYLVE 828


>gi|11426635 regulator of nonsense transcripts 1 [Homo sapiens]
           Length = 1118
           
 Score =  190 bits (478), Expect = 4e-47
 Identities = 158/497 (31%), Positives = 246/497 (48%), Gaps = 77/497 (15%)

Query: 171 LNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNK-VLATAESNVAVDN 229
           LN SQ  A+   L      L+ GP GTGKT T   ++    ++G + VL  A SN+AVD 
Sbjct: 471 LNHSQVYAVKTVL-QRPLSLIQGPPGTGKTVTSATIVYHLARQGCRPVLVCAPSNIAVDQ 529

Query: 230 LVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTY 289
           L E++ ++G+K+VR+   SR +     + LA       L+ ++R +              
Sbjct: 530 LTEKIHQTGLKVVRLCAKSREAIDSPVSFLA-------LHNQIRNMD------------- 569

Query: 290 TKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEER 349
                      S  E+ KL + K               E  +L+   +K +   R L+  
Sbjct: 570 -----------SMPELQKLQQLKD--------------ETGELSSADEKRY---RALKRT 601

Query: 350 IARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNK-VERFVLAG 408
             R+++  ADV+  T   A    +    +   +IDE+TQ+T P  ++P+    ++ +L G
Sbjct: 602 AERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVG 661

Query: 409 DHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGK 466
           DH QL P ++  +A +  LS++LFE L+     +   L VQYRM+  +  FPS  FY G 
Sbjct: 662 DHCQLGPVVMCKKAAKAGLSQSLFERLVV-LGIRPIRLQVQYRMHPALSAFPSNIFYEGS 720

Query: 467 IIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENP 526
           +       G+T  D V+ +  +  W +   P+  + F  T   E   E    G+ S  N 
Sbjct: 721 L-----QNGVTAADRVK-KGFDFQWPQ---PDKPMFFYVTQGQE---EIASSGT-SYLNR 767

Query: 527 LEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISM----------KVPEDVEVKTVD 576
            EA  V KI  KLL  G KP+ IG+ITPY+ QR  +            K+ ++VE+ +VD
Sbjct: 768 TEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVD 827

Query: 577 GYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKK 636
            +QGREK+ IILS VR+N+   IGFL D RRLNV+LTRA+  +I+VG+   LS    +  
Sbjct: 828 AFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNH 887

Query: 637 MIEFFKEKGCFIEFPFS 653
           ++ ++KE+   +E P +
Sbjct: 888 LLNYYKEQKVLVEGPLN 904


>gi|4506479 regulator of nonsense transcripts 1 [Homo sapiens]
           >gi|1575536|gb|AAC50771.1| (U65533) regulator of
           nonsense transcript stability [Homo sapiens]
           Length = 1118
           
 Score =  190 bits (477), Expect = 5e-47
 Identities = 159/497 (31%), Positives = 245/497 (48%), Gaps = 77/497 (15%)

Query: 171 LNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGN-KVLATAESNVAVDN 229
           LN SQ  A+   L      L+ GP GTGKT T   ++    ++ N  VL  A SN+AVD 
Sbjct: 471 LNHSQVYAVKTVL-QRPLSLIQGPPGTGKTVTSATIVYHLARQDNGPVLVCAPSNIAVDQ 529

Query: 230 LVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTY 289
           L E++ ++G+K+VR+   SR +     + LA       L+ ++R +              
Sbjct: 530 LTEKIHQTGLKVVRLCPKSREAIDSPVSFLA-------LHNQIRNMD------------- 569

Query: 290 TKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEER 349
                      S  E+ KL + K               E  +L+   +K +   R L+  
Sbjct: 570 -----------SMPELQKLQQLKD--------------ETGELSSADEKRY---RALKRT 601

Query: 350 IARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNK-VERFVLAG 408
             R+++  ADV+  T   A    +    +   +IDE+TQ+T P  ++P+    ++ +L G
Sbjct: 602 AERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVG 661

Query: 409 DHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGK 466
           DH QL P ++  +A +  LS++LFE L+     +   L VQYRM+  +  FPS  FY G 
Sbjct: 662 DHCQLGPVVMCKKAAKAGLSQSLFERLVV-LGIRPIRLQVQYRMHPALSAFPSNIFYEGS 720

Query: 467 IIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENP 526
           +       G+T  D V+ +  +  W +   P+  + F  T   E   E    G+ S  N 
Sbjct: 721 L-----QNGVTAADRVK-KGFDFQWPQ---PDKPMFFYVTQGQE---EIASSGT-SYLNR 767

Query: 527 LEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISM----------KVPEDVEVKTVD 576
            EA  V KI  KLL  G KP+ IG+ITPY+ QR  +            K+ ++VE+ +VD
Sbjct: 768 TEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVD 827

Query: 577 GYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKK 636
            +QGREK+ IILS VR+N+   IGFL D RRLNV+LTRA+  +I+VG+   LS    +  
Sbjct: 828 AFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNH 887

Query: 637 MIEFFKEKGCFIEFPFS 653
           ++ F+KE+   +E P +
Sbjct: 888 LLIFYKEQKVLVEGPLN 904


>sp|Q92355|YDHA_SCHPO HYPOTHETICAL 192.5 KD PROTEIN C6G9.10C IN CHROMOSOME I
            >gi|7490496|pir||T39072 DNA2-NAM7 helicase family protein
            - fission yeast  (Schizosaccharomyces pombe)
            >gi|1644322|emb|CAB03612.1| (Z81317) DNA2-NAM7 helicase
            family protein [Schizosaccharomyces pombe]
            Length = 1687
            
 Score =  184 bits (462), Expect = 3e-45
 Identities = 169/606 (27%), Positives = 284/606 (45%), Gaps = 95/606 (15%)

Query: 103  IVVALETVPEWALRDVRIDLYANDITFRRWLENLNTIKK--AGKRALRFYLGLDE----- 155
            ++V L T+P   + +    L  N   +   L NL T  +  AG R L ++   D+     
Sbjct: 1052 VLVVLRTLPSMEILN---KLQGNCALWFLKLTNLATFTRQYAGIRGLPYFHLADDIIRAR 1108

Query: 156  ------PSQGEEVNFVPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRT------- 202
                       E+        +N  Q KAI  AL +  F L+ GP GTGKT+T       
Sbjct: 1109 PCSQPVKHSSSEIKAAMKRYQVNEPQAKAIMCALDNNGFTLIQGPPGTGKTKTIIGIISA 1168

Query: 203  -LVELIRQEVKRGNK----------VLATAESNVAVDNLVERLSRSGI---------KIV 242
             LV+L R  + R N+          +L  A SN AVD ++ RL R  +         ++V
Sbjct: 1169 LLVDLSRYHITRPNQQSKSTESKQQILLCAPSNAAVDEVLLRLKRGFLLENGEKYIPRVV 1228

Query: 243  RIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIG--QSLAEKRDTYTKPTPKFRRGL 300
            RIG+P  ++  + + +L Y  T+ +L    +    +G  Q L   RDT+     K     
Sbjct: 1229 RIGNPETINVSVRDLSLEYQ-TEKQLLEVNQGAIDLGSLQELTRWRDTFYDCIQKI---- 1283

Query: 301  SDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARK-----------LEER 349
              EE+ K  +  R     +  L  E+   I      ++  ++ +            L ++
Sbjct: 1284 --EELEKQIDVARDVAEDTKSLGKELQNKINEKNLAEQKVEELQSQSFTKNKEVDLLRKK 1341

Query: 350  IARDIIREADVVLTTNSSAALEVVDYDT--YDVAIIDEATQSTIPSILIPLNK-VERFVL 406
              + I+++ADVV  T S +  ++V + +  +   IIDEA Q+     +IPL    ++ +L
Sbjct: 1342 AQKAILKQADVVCATLSGSGHDLVAHSSLNFSTVIIDEAAQAVELDTIIPLRYGAKKCIL 1401

Query: 407  AGDHKQLPPTILSLEAQEL--SRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYG 464
             GD  QLPPT+LS +A  L  S++LF  + + +  +  +L +QYRM+  I  FPSK+FY 
Sbjct: 1402 VGDPNQLPPTVLSKKAASLNYSQSLFVRIQKNFSNQMCLLSIQYRMHPDISHFPSKKFYD 1461

Query: 465  GKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRE 524
             ++   +++           +     W   +NP+    F      + + + +   + S  
Sbjct: 1462 SRLEDGDNMA----------EKTQQVWH--VNPK----FTQYRLFDVRGKERTSNTMSTY 1505

Query: 525  NPLEAEIVAKIVDKLLSIGVKPEW---IGVITPYDDQ----RDLISMKVPED----VEVK 573
            N  E E +  +VD+LL+      +   IGVITPY  Q    R    +K  +     ++++
Sbjct: 1506 NLEEVEYLVNMVDELLNKFPDVNFTGRIGVITPYRSQLHELRRAFKVKYGKSFMSTIDIQ 1565

Query: 574  TVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHET 633
            TVDG+QG+EK++I  S V+S     IGFL+D RRLNV+LTRA+  L+++G+  TL + + 
Sbjct: 1566 TVDGFQGQEKDIIFFSCVKSYSKHGIGFLRDFRRLNVALTRARSSLLIIGNMETLKTDDL 1625

Query: 634  YKKMIE 639
            +  +++
Sbjct: 1626 WGSLVD 1631


>emb|CAC10094.1| (AL442164) related to SEN1 protein [Neurospora crassa]
            Length = 1825
            
 Score =  174 bits (437), Expect = 2e-42
 Identities = 178/666 (26%), Positives = 301/666 (44%), Gaps = 130/666 (19%)

Query: 72   EISVGDLVVISK-RDPLK--------SDLLGTVVEKGKRFIVVALETVPEWALRDVRIDL 122
            ++S GD+V+ISK ++PL+        S +  T  +K    +V  L       L  +   L
Sbjct: 1033 QLSEGDIVIISKGQNPLQEPEELHCLSRIWKTTYKKDNVEVVYRLNAKGNQILPAL---L 1089

Query: 123  YANDITFRRWLENLNTIKK--AGKRALRFYLGLDEPSQGEEVNFVPFDK----------S 170
              ++ T  + + N+ TI++  A   +L++Y  +DE  + E    + F +          +
Sbjct: 1090 PGSEFTVVK-ITNMTTIEREYAALESLQYYDLMDEVLRAEPSPMLSFGEENIKNTMKNWN 1148

Query: 171  LNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELI----------------------- 207
            LN  Q KAI  A  ++ F L+ GP GTGKT+T+V ++                       
Sbjct: 1149 LNPGQAKAILNAKENDGFTLIQGPPGTGKTKTIVAMVGCLLTGVLKNPTAGVAIGRPGLG 1208

Query: 208  -RQEVKRGNKVLATAESNVAVDNLVERLSRSGIK----------IVRIGHPSRVSKHLHE 256
              +      K+L  A SN AVD LV RL ++G+K          +VR+G    ++  + +
Sbjct: 1209 AAKNNAPAKKLLVCAPSNAAVDELVLRL-KNGVKTQNGTTHQIEVVRLGRSDAINSAVKD 1267

Query: 257  TTLAYLI---------------TQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGLS 301
             TL  L+                + +L+ E  E++   Q +AE R     P  +  R + 
Sbjct: 1268 VTLDELVKAKLEAQLNKDEGPTDREKLHQEAGEIK---QKIAELR-----PQLEAARTID 1319

Query: 302  DEEIIKLAER-----KRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIR 356
            D +++   +R     KR    + AR+  + A      R+ +           ++ ++I+ 
Sbjct: 1320 DRQLVNKYQREFDELKRRQAHIGARIDADKASGNTFARETEIK-------RRQVQQEILD 1372

Query: 357  EADVVLTTNSSAALEV-----VDYDTYDVAIIDEATQSTIPSILIPLN-KVERFVLAGDH 410
            +A V+  T S +  E+     V+++T    IIDEA Q    S LIPL     + +L GD 
Sbjct: 1373 KAQVLCATLSGSGHEMFKNLNVEFET---VIIDEAAQCVELSALIPLKYGCSKCILVGDP 1429

Query: 411  KQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKII 468
            KQLPPT+LS  A      ++LF  + + +     +L  QYRM+  I  FP   FY G + 
Sbjct: 1430 KQLPPTVLSQSAARYGYDQSLFVRMQKNHEKDVHLLDTQYRMHPEISSFPRAAFYEGLLQ 1489

Query: 469  ADESVRGITLRDLVEYQSPNDSWGK--ILNPENVIVFIDTSKAENKWERQRRGSESRENP 526
              + +           +S    W +  +L P     F D   ++ +  + +      E  
Sbjct: 1490 DGDDMA----------KSRLQPWHRSTLLGPYR---FFDVRGSQERGPKNQSLVNEEELK 1536

Query: 527  LEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQ----RDLISMK----VPEDVEVKTVDGY 578
            +  ++  +      ++ +K + IG+ITPY  Q    R   + +    + +++E  T D +
Sbjct: 1537 VAMQLYRRFKADYGNVDLKGK-IGIITPYKAQLYRLRSQFAQRFGDAITDEIEFNTTDAF 1595

Query: 579  QGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMI 638
            QGRE E+II S VR++  G IGF+ D+RR+NV LTRA+  L ++GDS  L   E + K+I
Sbjct: 1596 QGRECEIIIFSCVRASPTGGIGFMTDIRRMNVGLTRARSSLWILGDSRALMQGEFWAKLI 1655

Query: 639  EFFKEK 644
            E  K +
Sbjct: 1656 EDSKRR 1661


>gb|AAB63976.1| (M74589) SEN1 [Saccharomyces cerevisiae]
            Length = 2112
            
 Score =  167 bits (419), Expect = 3e-40
 Identities = 155/549 (28%), Positives = 259/549 (46%), Gaps = 84/549 (15%)

Query: 161  EVNFVPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELI------------- 207
            E+  V     LN SQ +AI  ++  E F L+ GP GTGKT+T++ +I             
Sbjct: 1206 EIETVKKSYKLNTSQAEAIVNSVSKEGFSLIQGPPGTGKTKTILGIIGYFLSTKNASSSN 1265

Query: 208  ------------RQEVKRGNKVLATAESNVAVDNLVERLSRSGI----------KIVRIG 245
                         +++ +  K+L  A SN AVD +  RL +SG+          ++VR+G
Sbjct: 1266 VIKVPLEKNSSNTEQLLKKQKILICAPSNAAVDEICLRL-KSGVYDKQGHQFKPQLVRVG 1324

Query: 246  HPSRVSKHLHETTLAYLITQ------HELYGELRELRVIGQSLAEKRDTYTKPTPKF--- 296
                V+  + + TL  L+ +      +E+  +    R    ++ ++R+   K   +    
Sbjct: 1325 RSDVVNVAIKDLTLEELVDKRIGERNYEIRTDPELERKFNNAVTKRRELRGKLDSESGNP 1384

Query: 297  RRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIAR-DII 355
               +S E+I KL  + R      +++I E+       R+        R L+ R A+  I+
Sbjct: 1385 ESPMSTEDISKLQLKIREL----SKIINELGRDRDEMREKNSVNYRNRDLDRRNAQAHIL 1440

Query: 356  READVVLTTNSSAALEVVDYD--TYDVAIIDEATQSTIPSILIPLNKV-ERFVLAGDHKQ 412
              +D++ +T S +A +V+      +D  IIDEA Q T  S +IPL    +R ++ GD  Q
Sbjct: 1441 AVSDIICSTLSGSAHDVLATMGIKFDTVIIDEACQCTELSSIIPLRYGGKRCIMVGDPNQ 1500

Query: 413  LPPTILSLEAQELSRTLFEGLIERYPWKSE--MLVVQYRMNERIMEFPSKEFYGGKIIAD 470
            LPPT+LS  A        + L  R    S   +L VQYRM+  I +FPS EFY G++   
Sbjct: 1501 LPPTVLSGAASNFKYN--QSLFVRMEKNSSPYLLDVQYRMHPSISKFPSSEFYQGRLKDG 1558

Query: 471  ESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAE 530
              +  +  R           W + L P     F D        + Q   + S  N  E  
Sbjct: 1559 PGMDILNKRP----------WHQ-LEPLAPYKFFDIISGR---QEQNAKTMSYTNMEEIR 1604

Query: 531  IVAKIVDKLL-SIGVKPEW---IGVITPYDDQRDLISMK--------VPEDVEVKTVDGY 578
            +  ++VD L      K ++   IG+I+PY +Q   +  +        + + ++  T+DG+
Sbjct: 1605 VAIELVDYLFRKFDNKIDFTGKIGIISPYREQMQKMRKEFARYFGGMINKSIDFNTIDGF 1664

Query: 579  QGREKEVIILSLVRSNKL-GEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKM 637
            QG+EKE+I++S VR++     +GFLKD RR+NV+LTRAK  + V+G   +L+  + ++ +
Sbjct: 1665 QGQEKEIILISCVRADDTKSSVGFLKDFRRMNVALTRAKTSIWVLGHQRSLAKSKLWRDL 1724

Query: 638  IEFFKEKGC 646
            IE  K++ C
Sbjct: 1725 IEDAKDRSC 1733


>gi|6323462 component of a nuclear-localized tRNA splicing complex; Sen1p
            [Saccharomyces cerevisiae]
            >gi|3123282|sp|Q00416|SEN1_YEAST TRNA-SPLICING
            ENDONUCLEASE POSITIVE EFFECTOR >gi|1078364|pir||S53416
            SEN1 protein - yeast (Saccharomyces cerevisiae)
            >gi|664872|gb|AAB67502.1| (U20939) Sen1p [Saccharomyces
            cerevisiae]
            Length = 2231
            
 Score =  167 bits (419), Expect = 3e-40
 Identities = 155/549 (28%), Positives = 259/549 (46%), Gaps = 84/549 (15%)

Query: 161  EVNFVPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELI------------- 207
            E+  V     LN SQ +AI  ++  E F L+ GP GTGKT+T++ +I             
Sbjct: 1325 EIETVKKSYKLNTSQAEAIVNSVSKEGFSLIQGPPGTGKTKTILGIIGYFLSTKNASSSN 1384

Query: 208  ------------RQEVKRGNKVLATAESNVAVDNLVERLSRSGI----------KIVRIG 245
                         +++ +  K+L  A SN AVD +  RL +SG+          ++VR+G
Sbjct: 1385 VIKVPLEKNSSNTEQLLKKQKILICAPSNAAVDEICLRL-KSGVYDKQGHQFKPQLVRVG 1443

Query: 246  HPSRVSKHLHETTLAYLITQ------HELYGELRELRVIGQSLAEKRDTYTKPTPKF--- 296
                V+  + + TL  L+ +      +E+  +    R    ++ ++R+   K   +    
Sbjct: 1444 RSDVVNVAIKDLTLEELVDKRIGERNYEIRTDPELERKFNNAVTKRRELRGKLDSESGNP 1503

Query: 297  RRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIAR-DII 355
               +S E+I KL  + R      +++I E+       R+        R L+ R A+  I+
Sbjct: 1504 ESPMSTEDISKLQLKIREL----SKIINELGRDRDEMREKNSVNYRNRDLDRRNAQAHIL 1559

Query: 356  READVVLTTNSSAALEVVDYD--TYDVAIIDEATQSTIPSILIPLNKV-ERFVLAGDHKQ 412
              +D++ +T S +A +V+      +D  IIDEA Q T  S +IPL    +R ++ GD  Q
Sbjct: 1560 AVSDIICSTLSGSAHDVLATMGIKFDTVIIDEACQCTELSSIIPLRYGGKRCIMVGDPNQ 1619

Query: 413  LPPTILSLEAQELSRTLFEGLIERYPWKSE--MLVVQYRMNERIMEFPSKEFYGGKIIAD 470
            LPPT+LS  A        + L  R    S   +L VQYRM+  I +FPS EFY G++   
Sbjct: 1620 LPPTVLSGAASNFKYN--QSLFVRMEKNSSPYLLDVQYRMHPSISKFPSSEFYQGRLKDG 1677

Query: 471  ESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAE 530
              +  +  R           W + L P     F D        + Q   + S  N  E  
Sbjct: 1678 PGMDILNKRP----------WHQ-LEPLAPYKFFDIISGR---QEQNAKTMSYTNMEEIR 1723

Query: 531  IVAKIVDKLL-SIGVKPEW---IGVITPYDDQRDLISMK--------VPEDVEVKTVDGY 578
            +  ++VD L      K ++   IG+I+PY +Q   +  +        + + ++  T+DG+
Sbjct: 1724 VAIELVDYLFRKFDNKIDFTGKIGIISPYREQMQKMRKEFARYFGGMINKSIDFNTIDGF 1783

Query: 579  QGREKEVIILSLVRSNKL-GEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKM 637
            QG+EKE+I++S VR++     +GFLKD RR+NV+LTRAK  + V+G   +L+  + ++ +
Sbjct: 1784 QGQEKEIILISCVRADDTKSSVGFLKDFRRMNVALTRAKTSIWVLGHQRSLAKSKLWRDL 1843

Query: 638  IEFFKEKGC 646
            IE  K++ C
Sbjct: 1844 IEDAKDRSC 1852


>gb|AAG19799.1| (AE005064) DNA helicase; Hel [Halobacterium sp. NRC-1]
           Length = 821
           
 Score =  167 bits (418), Expect = 4e-40
 Identities = 109/287 (37%), Positives = 155/287 (53%), Gaps = 22/287 (7%)

Query: 355 IREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLP 414
           +R A VV  T ++    ++    +DV ++DEA+Q T P  L  +N+  RFVL GDH+QLP
Sbjct: 552 LRSAPVVAATTATCGSRILRELEFDVVLVDEASQLTEPDTLAAINRGARFVLVGDHEQLP 611

Query: 415 PTILSLEAQELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKI-IADESV 473
           P + S     LS++LFE L E YP  S ML  QYRM++RI  F S+EFY G++  A   V
Sbjct: 612 PVVRS--GGRLSKSLFERLHETYPEASVMLDQQYRMSQRIQAFSSREFYDGQLRPASSEV 669

Query: 474 RGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVA 533
            G  L D+       D  G +      + F D    +          ++  +P EA+ VA
Sbjct: 670 AGQRLTDV-----GVDPGGAV---HGGVTFYDVPGTD----------DAHVDPAEADRVA 711

Query: 534 KIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRS 593
            +V   +  G+ P  IGVI P+  Q   I  + P  V V TVD +QG  KEVI++S V  
Sbjct: 712 DVVTAYVDAGLDPGEIGVIAPFRAQVAEIGRRTPAGVAVDTVDRFQGSSKEVIVVSFVAR 771

Query: 594 NKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEF 640
             L E    +D RR+NV+L+RAK+ L++VGD   L S   Y +MI++
Sbjct: 772 GTL-EGPIFEDHRRVNVALSRAKKSLVLVGDERALRSEPLYDRMIDW 817


 Score = 86.2 bits (210), Expect = 1e-15
 Identities = 81/283 (28%), Positives = 137/283 (47%), Gaps = 12/283 (4%)

Query: 5   SFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGE-ELGYFLVKY 63
           ++ + L + +E ER A  +  R ++   S  ER    RA++ L+     E   G + +  
Sbjct: 289 AYFDELYDAIEAERGAIHDEYR-KLWEQSPDERAADDRAVVGLSPAEQTELPDGRWRLTA 347

Query: 64  GRNREIKTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWALRDVRIDLY 123
            R     ++I  GD V+ S  DP+        VE   R     +E   +  +   R+D+Y
Sbjct: 348 TRPGSAASKIREGDRVLASDGDPVAGRAEMARVE---RLDADRVEVTTDEPVSLCRLDVY 404

Query: 124 ANDITFRRWLENLN-TIKKAGKRALRFYLGLDEPS-QGEEVNFVPFDKSLNRSQRKAISK 181
            ++++  R L  L+  + K+ +R          P  +G + + +P     N +Q  A+++
Sbjct: 405 PSELSVDRMLTALHDAVLKSDQRRTDLLFDRASPRFEGGDHDLIPN----NDAQNAAVNR 460

Query: 182 ALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLSRSGIK- 240
           AL +EDF LVHGP GTGKT T+  L++  V RG++VL +A +N AVDN ++ L + G + 
Sbjct: 461 ALNAEDFALVHGPPGTGKTYTIATLVQAFVARGDRVLVSAFTNRAVDNALDALRQQGHED 520

Query: 241 IVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLA 283
           IVR+G  + V   + +  L       E    LR   V+  + A
Sbjct: 521 IVRVGTETGVRADMQDLRLDRSGDPGERAAALRSAPVVAATTA 563


>gi|6321024 DNA Helicase I; Ecm32p [Saccharomyces cerevisiae]
            >gi|418429|sp|P32644|YE06_YEAST HYPOTHETICAL 127.0 KD
            PROTEIN IN RAD24-BMH1 INTERGENIC REGION
            >gi|320741|pir||S30862 DNA dependent ATPase/DNA helicase
            B - yeast (Saccharomyces cerevisiae)
            >gi|603417|gb|AAB64703.1| (U18922) Yer176wp
            [Saccharomyces cerevisiae]
            Length = 1121
            
 Score =  161 bits (402), Expect = 3e-38
 Identities = 157/531 (29%), Positives = 238/531 (44%), Gaps = 125/531 (23%)

Query: 171  LNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNK--VLATAESNVAVD 228
            LNRSQ+ A+   L +    ++ GP GTGKT T+ E+I Q ++R +   +L  A SN+A+D
Sbjct: 649  LNRSQKTAVEHVLNNS-ITILQGPPGTGKTSTIEEIIIQVIERFHAFPILCVAASNIAID 707

Query: 229  NLVERL--SRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELR-ELRVIGQSLAEK 285
            N+ E++  +R  IKI+RI    +  ++  +  L  +   + +Y  L  +++V+       
Sbjct: 708  NIAEKIMENRPQIKILRILSKKKEQQYSDDHPLGEICLHNIVYKNLSPDMQVVAN----- 762

Query: 286  RDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARK 345
                     K RRG    E+I  +E  +                               K
Sbjct: 763  ---------KTRRG----EMISKSEDTK-----------------------------FYK 780

Query: 346  LEERIARDIIREADVVLTTNSSAA-LEVVDYDTYDVAIIDEATQSTIPSILIPLNK--VE 402
             + R+   ++ ++ ++ TTN +A   E+       V I+DEATQS+  S L+PL+   + 
Sbjct: 781  EKNRVTNKVVSQSQIIFTTNIAAGGRELKVIKECPVVIMDEATQSSEASTLVPLSLPGIR 840

Query: 403  RFVLAGDHKQLPPTILSLEAQELSRTLFEGLIERYPWKSE-MLVVQYRMNERIMEFPSKE 461
             FV  GD KQL          +L  +LFE ++    +K+  ML  QYRM+ +I EFP K+
Sbjct: 841  NFVFVGDEKQLSSFS---NIPQLETSLFERVLSNGTYKNPLMLDTQYRMHPKISEFPIKK 897

Query: 462  FYGGKI---IADESVR--GITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQ 516
             Y G++   + DE     G+    L  YQ       ++ + +  IV       ENK E  
Sbjct: 898  IYNGELKDGVTDEQKAWPGVQ-HPLFFYQCDLGPESRVRSTQRDIVGF---TYENKHEC- 952

Query: 517  RRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLIS------------- 563
                         EIV  I   +L   V  E IGVITPY  QRDL+S             
Sbjct: 953  ------------VEIVKIIQILMLDKKVPLEEIGVITPYSAQRDLLSDILTKNVVINPKQ 1000

Query: 564  -----------------------------MKVPEDVEVKTVDGYQGREKEVIILSLVRSN 594
                                         + +   + V TVD +QG EK  II S VR+N
Sbjct: 1001 ISMQQEYDEIELFNAAGSQGTAGSLQNNVINIINGLHVATVDSFQGHEKSFIIFSCVRNN 1060

Query: 595  KLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHE-TYKKMIEFFKEK 644
               +IGFL+D RRLNV+LTRAK  LIVVG+ + L   +  +K  I + +E+
Sbjct: 1061 TENKIGFLRDKRRLNVALTRAKHGLIVVGNKNVLRKGDPLWKDYITYLEEQ 1111


>pir||T39568 hypothetical helicase - fission yeast (Schizosaccharomyces pombe)
            >gi|4481950|emb|CAB38508.1| (AL035637) dna replication
            helicase [Schizosaccharomyces pombe]
            Length = 1398
            
 Score =  159 bits (397), Expect = 1e-37
 Identities = 106/318 (33%), Positives = 168/318 (52%), Gaps = 22/318 (6%)

Query: 340  FDDARKLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLN 399
            FDD   L+         +  +V  ++      + +   +D  IIDEA+Q  +P  L PL 
Sbjct: 1027 FDDLASLKH-----FYEDPQIVACSSLGVYHSIFNKRKFDYCIIDEASQIPLPICLGPLQ 1081

Query: 400  KVERFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEF 457
              E+FVL GDH QLPP + +    +  LS +LF+ L E++P     L +QYRMNE I   
Sbjct: 1082 LAEKFVLVGDHYQLPPLVKNSRTSKDGLSLSLFKLLSEKHPEAVTTLRLQYRMNEDINSL 1141

Query: 458  PSKEFYGGKIIADES--------VRGITLRDLVEYQSPNDSW-GKILNPENVIVFIDTSK 508
             S+  YGG ++            +    L D +   S +  W  K++NP + ++F +T  
Sbjct: 1142 SSELIYGGNLVCGSKTISQKKLILPKAHLSDGLPDSSSSLHWVNKLINPSHSVIFFNT-- 1199

Query: 509  AENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLIS--MKV 566
             ++    + + +   EN  EA ++ + V   L  GVK   IG+I+ Y  Q +L+S  +K 
Sbjct: 1200 -DDILGVESKTNNILENHTEAFLIEQAVSSFLERGVKQSSIGIISIYKSQVELLSKNLKS 1258

Query: 567  PEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIG-FLKDLRRLNVSLTRAKRKLIVVGDS 625
              ++E+ TVD YQGR+K++I++S VRSN    +G  L+D  RLNV+L+RAK K I+ G  
Sbjct: 1259 FTEIEINTVDRYQGRDKDIILISFVRSNSKNLVGELLRDWHRLNVALSRAKVKCIMFGSL 1318

Query: 626  STLSSHETYKKMIEFFKE 643
            STLSS      +++  ++
Sbjct: 1319 STLSSSNIVSHLLKLLEK 1336


>pir||T51292 Dna2p - fission yeast (Schizosaccharomyces pombe)
            >gi|5052396|gb|AAD38528.1|AF144384_1 (AF144384) Dna2p
            [Schizosaccharomyces pombe]
            Length = 1397
            
 Score =  159 bits (397), Expect = 1e-37
 Identities = 106/318 (33%), Positives = 168/318 (52%), Gaps = 22/318 (6%)

Query: 340  FDDARKLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLN 399
            FDD   L+         +  +V  ++      + +   +D  IIDEA+Q  +P  L PL 
Sbjct: 1026 FDDLASLKH-----FYEDPQIVACSSLGVYHSIFNKRKFDYCIIDEASQIPLPICLGPLQ 1080

Query: 400  KVERFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEF 457
              E+FVL GDH QLPP + +    +  LS +LF+ L E++P     L +QYRMNE I   
Sbjct: 1081 LAEKFVLVGDHYQLPPLVKNSRTSKDGLSLSLFKLLSEKHPEAVTTLRLQYRMNEDINSL 1140

Query: 458  PSKEFYGGKIIADES--------VRGITLRDLVEYQSPNDSW-GKILNPENVIVFIDTSK 508
             S+  YGG ++            +    L D +   S +  W  K++NP + ++F +T  
Sbjct: 1141 SSELIYGGNLVCGSKTISQKKLILPKAHLSDGLPDSSSSLHWVNKLINPSHSVIFFNT-- 1198

Query: 509  AENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLIS--MKV 566
             ++    + + +   EN  EA ++ + V   L  GVK   IG+I+ Y  Q +L+S  +K 
Sbjct: 1199 -DDILGVESKTNNILENHTEAFLIEQAVSSFLERGVKQSSIGIISIYKSQVELLSKNLKS 1257

Query: 567  PEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIG-FLKDLRRLNVSLTRAKRKLIVVGDS 625
              ++E+ TVD YQGR+K++I++S VRSN    +G  L+D  RLNV+L+RAK K I+ G  
Sbjct: 1258 FTEIEINTVDRYQGRDKDIILISFVRSNSKNLVGELLRDWHRLNVALSRAKVKCIMFGSL 1317

Query: 626  STLSSHETYKKMIEFFKE 643
            STLSS      +++  ++
Sbjct: 1318 STLSSSNIVSHLLKLLEK 1335


>gb|AAF99770.1|AC003981_20 (AC003981) F22O13.33 [Arabidopsis thaliana]
           Length = 865
           
 Score =  158 bits (396), Expect = 2e-37
 Identities = 117/326 (35%), Positives = 171/326 (51%), Gaps = 26/326 (7%)

Query: 312 KRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREADVVLTTNSSAALE 371
           K   R LS  +++E   + K   +V  AF D +K  +++         VV +T       
Sbjct: 508 KNTCRELSFYVLVETRLYTKKFEKV--AFQDIKKKLDQVK--------VVASTCLGINSP 557

Query: 372 VVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSLEAQE--LSRTL 429
           ++    +DV IIDEA Q  +P  + PL     FVL GDH QLPP + S EA+E  +  +L
Sbjct: 558 LLVNRRFDVCIIDEAGQIALPVSIGPLLFASTFVLVGDHYQLPPLVQSTEARENGMGISL 617

Query: 430 FEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADES-VRGITLRDLVEYQSPN 488
           F  L E +P    +L  QYRM   IME  +   YG ++    + V   TL  ++   S  
Sbjct: 618 FRRLSEAHPQAISVLQNQYRMCRGIMELSNALIYGDRLCCGSAEVADATL--VLSTSSST 675

Query: 489 DSW-GKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPE 547
             W  K+L P   +VF++T         + R   +  NP+EA I+A   ++L++ GV  +
Sbjct: 676 SPWLKKVLEPTRTVVFVNTDMLR---AFEARDQNAINNPVEASIIA---EELVNNGVDSK 729

Query: 548 WIGVITPYDDQRDLISMKVP-EDVEVKTVDGYQGREKEVIILSLVRSN---KLGEIGFLK 603
            IG+ITPY+ Q  LI   +P   VE+ T+D YQGR+K+ I++S VRS    +      L 
Sbjct: 730 DIGIITPYNSQASLIQHAIPTTPVEIHTIDKYQGRDKDCILVSFVRSREKPRSSASSLLG 789

Query: 604 DLRRLNVSLTRAKRKLIVVGDSSTLS 629
           D  R+NV+LTRAK+KLI+VG   TLS
Sbjct: 790 DWHRINVALTRAKKKLIMVGSQRTLS 815


>sp|P51530|Y083_HUMAN HYPOTHETICAL PROTEIN KIAA0083 >gi|11360302|pir||T50697 hypothetical
            protein KIAA0083 [imported] - human (fragment)
            >gi|1531548|dbj|BAA07647.1| (D42046) The ha3631 gene
            product is related to S.cerevisiae protein encoded in
            chromosome VIII. [Homo sapiens]
            Length = 1077
            
 Score =  158 bits (395), Expect = 2e-37
 Identities = 110/310 (35%), Positives = 166/310 (53%), Gaps = 22/310 (7%)

Query: 360  VVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILS 419
            +V TT       +     +D  I+DEA+Q + P  L PL    RFVL GDH+QLPP +L+
Sbjct: 755  IVATTCMGINHPIFSRKIFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLN 814

Query: 420  LEAQEL--SRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKI------IADE 471
             EA+ L  S +LF+ L E+       L VQYRMN +IM   +K  Y GK+      +A+ 
Sbjct: 815  REARALGMSESLFKRL-EQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANA 873

Query: 472  SVRGITLRDL---VEY---QSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESREN 525
             +     +D+   +E+    S N     +  P N + F++T K     E+  +G  S  N
Sbjct: 874  VINLRHFKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAP-EQVEKGGVS--N 930

Query: 526  PLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPED---VEVKTVDGYQGRE 582
              EA+++  +    +  G  P  IG+I PY  Q  +I+  +      VEV TVD YQGR+
Sbjct: 931  VTEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRD 990

Query: 583  KEVIILSLVRSNKLGEIG-FLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFF 641
            K ++++S VRSNK G +G  LKD RRLNV++TRAK KLI++G   +L+ +   +K++   
Sbjct: 991  KSIVLVSFVRSNKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHL 1050

Query: 642  KEKGCFIEFP 651
              +   I+ P
Sbjct: 1051 NSEKLIIDLP 1060


>pir||T08986 hypothetical protein F6G3.130 - Arabidopsis thaliana
            >gi|4938486|emb|CAB43845.1| (AL078464) putative protein
            [Arabidopsis thaliana] >gi|7269910|emb|CAB81003.1|
            (AL161576) putative protein [Arabidopsis thaliana]
            Length = 1311
            
 Score =  157 bits (392), Expect = 5e-37
 Identities = 147/482 (30%), Positives = 235/482 (48%), Gaps = 64/482 (13%)

Query: 216  KVLATAESNVAVDNLVERLSRSGI----------KIVRIGHPSRVSKHL-----HETTLA 260
            ++L  A SN A D L+ R+   G            + R+G  ++            + L 
Sbjct: 743  RMLVCAPSNAATDELLSRVLDRGFIDGEMRVYRPDVARVGVDTQTKAAQAVSVERRSDLL 802

Query: 261  YLITQHELYGELRELRVIGQSLAE-----KRDTYTKPTPKFRRGLS--DEEIIKLAERKR 313
               ++ E+ G +  LRV    L++     KR+          +G    D +++ + ++ R
Sbjct: 803  LAKSREEILGHIHNLRVRDAQLSQDIAGLKRELTAAAFANRSQGSVGVDPDVLMVRDQTR 862

Query: 314  GA--RGLSARLIMEMAEWIKLNRQ--VQKAFDDARKLEERIAR-----DIIREADVVLTT 364
             A  + LSA +     + ++++R   V+  F          AR         EA++V TT
Sbjct: 863  DAMLQRLSAVVEARDKDLVEMSRLLIVEGKFRAGTSFNLEEARASLEASFANEAEIVFTT 922

Query: 365  NSSAALEVVDYDT--YDVAIIDEATQSTIPSILIPLNK-VERFVLAGDHKQLPPTILSLE 421
             SS+  ++    T  +D+ +IDEA Q++   +L PL     R VL GD +QLP T++S  
Sbjct: 923  VSSSGRKLFSRLTHGFDMVVIDEAAQASEVGVLPPLALGAARCVLVGDPQQLPATVISKA 982

Query: 422  AQEL--SRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLR 479
            A  L  SR+LFE   +     + +L VQYRM+ +I +FPS+ FY G++   ESV   T  
Sbjct: 983  AGTLLYSRSLFERF-QLAGCPTLLLTVQYRMHPQIRDFPSRYFYQGRLTDSESVS--TAP 1039

Query: 480  DLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAE----IVAKI 535
            D + Y+        +L P    +F D S      E  R GS S EN  EA     +   +
Sbjct: 1040 DEIYYKD------SVLKP---YLFFDISHGR---ESHRGGSVSYENIDEARFCVGVYLHL 1087

Query: 536  VDKLLSIGVKPEWIGVITPYDDQR--------DLISMKVPEDVEVKTVDGYQGREKEVII 587
               L S+G     +GVITPY  Q         + +S    +++ + TVD +QG+E++VII
Sbjct: 1088 QRTLKSLGGGKVSVGVITPYKLQLKCLKIEFGNALSQDELQEIYINTVDAFQGQERDVII 1147

Query: 588  LSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGCF 647
            +S VR++  G +GF+ D+RR+NV+LTRAKR L V+G++S L   E +  +I   K + CF
Sbjct: 1148 MSCVRASNHG-VGFVADIRRMNVALTRAKRALWVMGNASALMKCEDWAALITDAKARNCF 1206

Query: 648  IE 649
            +E
Sbjct: 1207 ME 1208


>pir||T26415 hypothetical protein Y106G6D.5 - Caenorhabditis elegans
           >gi|3880678|emb|CAA20978.1| (AL031629) cDNA EST
           EMBL:T00167 comes from this gene~cDNA EST yk384f3.3
           comes from this gene~cDNA EST yk287a1.5 comes from this
           gene~cDNA EST yk384f3.5 comes from this gene
           [Caenorhabditis elegans]
           Length = 693
           
 Score =  153 bits (383), Expect = 5e-36
 Identities = 97/294 (32%), Positives = 168/294 (56%), Gaps = 16/294 (5%)

Query: 360 VVLTTNSSAALEVVDYD-TYDVAIIDEATQSTIPSILIPL---NKVERFVLAGDHKQLPP 415
           V  T  +S+  ++ +Y    DV I+DEA Q T P+  +P+      ++ +L GD KQLP 
Sbjct: 381 VFSTLGTSSIQKLPEYHWNADVMIVDEAAQCTEPATWVPVLTTPSCKKLILVGDQKQLPA 440

Query: 416 TILSLEAQE--LSRTLFEGLIERYPWKSEMLVV--QYRMNERIMEFPSKEFYGGKIIADE 471
            +LS +A +     +L E L E +   +  +++  QYRMN++IM + ++ FY  ++ A  
Sbjct: 441 VVLSDKAMKGNFKLSLMEKLAEEFSSNNINILLNEQYRMNKKIMNWSNEVFYENQLTAHS 500

Query: 472 SVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEI 531
           +V  ITLRD+     PN     +LN  N I+ I+    +++   +   S S  N  E  +
Sbjct: 501 TVSDITLRDIC----PNLPEDHVLN--NPIMMINMENVKDR-SHEEFESHSFTNTDELNL 553

Query: 532 VAKIVDKLL-SIGVKPEWIGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSL 590
           V + V++L+  +G+ P+ I VI+PY  Q + +   +P  V+V TVD +QG E++V+I  L
Sbjct: 554 VTEYVNRLVVDLGINPKAIAVISPYYAQIEKLRRSIPFRVDVNTVDAFQGHERQVVIFCL 613

Query: 591 VRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEK 644
           VR N  G+IGFL + RRLNV++TRA+R+ +++G+   +  ++   K+ +  + +
Sbjct: 614 VRDNDEGQIGFLNETRRLNVAVTRARRQFVLIGNGRMMKGNKHLLKLYKHLQSE 667


>pir||T00533 SEN1 protein homolog T20K24.14 - Arabidopsis thaliana
            >gi|3176714|gb|AAD12029.1| (AC002392) putative DNA2-NAM7
            helicase family protein [Arabidopsis thaliana]
            Length = 1090
            
 Score =  152 bits (379), Expect = 2e-35
 Identities = 147/483 (30%), Positives = 236/483 (48%), Gaps = 66/483 (13%)

Query: 216  KVLATAESNVAVDNLVERLSRSGI----------KIVRIGHPSR------VSKHLHETTL 259
            ++L  A SN A D L+ R+   G            + R+G  S+      VS       L
Sbjct: 580  RMLVCAPSNAATDELLSRVLDRGFIDGEMRVYRPDVARVGVDSQSRAAQAVSVERRSDQL 639

Query: 260  AYLITQHELYGELRELRV----IGQSLAE-KRDTYTKPTPKFRRGLS--DEEIIKLAERK 312
               I++ E+   +R LR+    I Q++A  KR+          +G    D E++   ++K
Sbjct: 640  L-AISRDEILRHMRNLRLQETQISQNIAGLKRELNAAAFATRSQGSVGVDPEVLISRDQK 698

Query: 313  RGARGLSARLIMEMAE--WIKLNRQ--VQKAFDDARKLEERIAR-----DIIREADVVLT 363
            R A       ++E  +   ++++R   V+  F          AR         EA++V T
Sbjct: 699  RDALLQHLAAVVEARDKVLVEISRLLIVEGKFRAGNNFNLEEARASLEASFANEAEIVFT 758

Query: 364  TNSSAALEVVDYDT--YDVAIIDEATQSTIPSILIPLNK-VERFVLAGDHKQLPPTILSL 420
            T SS+  ++    T  +D+ +IDEA Q++   +L PL     R VL GD +QLP T++S 
Sbjct: 759  TVSSSGRKLFSRLTHGFDMVVIDEAAQASEVGVLPPLALGAARCVLVGDPQQLPATVISK 818

Query: 421  EAQEL--SRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITL 478
             A  L  SR+LFE   +     + +L VQYRM+ +I +FPS+ FY G++   ES+     
Sbjct: 819  AAGTLLYSRSLFERF-QLAGCPTLLLTVQYRMHPQIRDFPSRYFYQGRLKDSESISSAP- 876

Query: 479  RDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAE----IVAK 534
             D + Y+ P      +L P    +F + S      E  R GS S EN  EA     +   
Sbjct: 877  -DEIYYKDP------VLRP---YLFFNISHGR---ESHRGGSVSYENVDEARFCVGVYMH 923

Query: 535  IVDKLLSIGVKPEWIGVITPYDDQRDLISMKVP--------EDVEVKTVDGYQGREKEVI 586
            +   L S+G     +GVITPY  Q   +  +          +++ + TVD +QG+E++VI
Sbjct: 924  LQKTLKSLGAGKVSVGVITPYKLQLKCLKHEFGNALGQDELKEIYINTVDAFQGQERDVI 983

Query: 587  ILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGC 646
            I+S VR++  G +GF+ D+RR+NV+LTRA+R L V+G++S L   E +  +I   + + C
Sbjct: 984  IMSCVRASGHG-VGFVSDIRRMNVALTRARRALWVMGNASALMKSEDWAALISDARGRNC 1042

Query: 647  FIE 649
            F+E
Sbjct: 1043 FME 1045


>dbj|BAA31600.1| (AB014525) KIAA0625 protein [Homo sapiens]
           Length = 791
           
 Score =  148 bits (369), Expect = 2e-34
 Identities = 143/561 (25%), Positives = 255/561 (44%), Gaps = 115/561 (20%)

Query: 165 VPFDKSLNRSQRKAISKALGS-------EDFFLVHGPFGTGKTRTLV----ELIRQEVKR 213
           + + +  N  Q+KAI  A              L+HGP GTGK++T+V     L+ +  ++
Sbjct: 42  IAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRK 101

Query: 214 G------------NKVLATAESNVAVDNLVERL----------------SRSGIKIVRIG 245
           G            N+VL  A SN AVD L++++                +   I +VR+G
Sbjct: 102 GHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLG 161

Query: 246 HPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGLSDEEI 305
                 K ++   L + +     +   +EL    Q++ ++++              D ++
Sbjct: 162 P----EKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKE------------FLDYQL 205

Query: 306 IKLAERKRGARGLSARLIMEMAEWI-KLNRQVQKAFDDARKLEERIARD---IIREADVV 361
            +L+ ++   RG       E+ E I K++++ Q+     ++++ R  +    II E+ ++
Sbjct: 206 DELSRQRALCRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHII 265

Query: 362 LTTNSSAALEVVDYD-------TYDVAIIDEATQSTIPSILIPL-NKVERFVLAGDHKQL 413
             T S++   +++          +   I+DEA QS     L PL ++  + +L GD KQL
Sbjct: 266 CCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQL 325

Query: 414 PPTILSLEAQE--------------LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPS 459
           PPT++S++AQE              L   +   +I R P     L VQYRM+  I  FPS
Sbjct: 326 PPTVISMKAQEYGYDQSMMARFCRLLEENVEHNMISRLPILQ--LTVQYRMHPDICLFPS 383

Query: 460 KEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRG 519
              Y   +  +     I           +  W     P    +  D          +RR 
Sbjct: 384 NYVYNRNLKTNRQTEAIRC---------SSDW-----PFQPYLVFDVGDGS-----ERRD 424

Query: 520 SESRENPLEAEIVAKIV----DKLLSIGVKPEWIGVITPYDDQRDLISMKVPED------ 569
           ++S  N  E ++V +I+    DK   +  +   IG+IT Y  Q+ +I   + ++      
Sbjct: 425 NDSYINVQEIKLVMEIIKLIKDKRKDVSFRN--IGIITHYKAQKTMIQKDLDKEFDRKGP 482

Query: 570 VEVKTVDGYQGREKEVIILSLVRSNKL-GEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL 628
            EV TVD +QGR+K+ +I++ VR+N + G IGFL  L+RLNV++TRAK  L ++G   TL
Sbjct: 483 AEVDTVDAFQGRQKDCVIVTCVRANSIQGSIGFLASLQRLNVTITRAKYSLFILGHLRTL 542

Query: 629 SSHETYKKMIEFFKEKGCFIE 649
             ++ + ++I+  +++G  I+
Sbjct: 543 MENQHWNQLIQDAQKRGAIIK 563


>gi|7662212 KIAA0625 protein [Homo sapiens] >gi|7022724|dbj|BAA91701.1|
           (AK001456) unnamed protein product [Homo sapiens]
           Length = 828
           
 Score =  148 bits (369), Expect = 2e-34
 Identities = 143/561 (25%), Positives = 255/561 (44%), Gaps = 115/561 (20%)

Query: 165 VPFDKSLNRSQRKAISKALGS-------EDFFLVHGPFGTGKTRTLV----ELIRQEVKR 213
           + + +  N  Q+KAI  A              L+HGP GTGK++T+V     L+ +  ++
Sbjct: 79  IAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRK 138

Query: 214 G------------NKVLATAESNVAVDNLVERL----------------SRSGIKIVRIG 245
           G            N+VL  A SN AVD L++++                +   I +VR+G
Sbjct: 139 GHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLG 198

Query: 246 HPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGLSDEEI 305
                 K ++   L + +     +   +EL    Q++ ++++              D ++
Sbjct: 199 P----EKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKE------------FLDYQL 242

Query: 306 IKLAERKRGARGLSARLIMEMAEWI-KLNRQVQKAFDDARKLEERIARD---IIREADVV 361
            +L+ ++   RG       E+ E I K++++ Q+     ++++ R  +    II E+ ++
Sbjct: 243 DELSRQRALCRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHII 302

Query: 362 LTTNSSAALEVVDYD-------TYDVAIIDEATQSTIPSILIPL-NKVERFVLAGDHKQL 413
             T S++   +++          +   I+DEA QS     L PL ++  + +L GD KQL
Sbjct: 303 CCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQL 362

Query: 414 PPTILSLEAQE--------------LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPS 459
           PPT++S++AQE              L   +   +I R P     L VQYRM+  I  FPS
Sbjct: 363 PPTVISMKAQEYGYDQSMMARFCRLLEENVEHNMISRLPILQ--LTVQYRMHPDICLFPS 420

Query: 460 KEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRG 519
              Y   +  +     I           +  W     P    +  D          +RR 
Sbjct: 421 NYVYNRNLKTNRQTEAIRC---------SSDW-----PFQPYLVFDVGDGS-----ERRD 461

Query: 520 SESRENPLEAEIVAKIV----DKLLSIGVKPEWIGVITPYDDQRDLISMKVPED------ 569
           ++S  N  E ++V +I+    DK   +  +   IG+IT Y  Q+ +I   + ++      
Sbjct: 462 NDSYINVQEIKLVMEIIKLIKDKRKDVSFRN--IGIITHYKAQKTMIQKDLDKEFDRKGP 519

Query: 570 VEVKTVDGYQGREKEVIILSLVRSNKL-GEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL 628
            EV TVD +QGR+K+ +I++ VR+N + G IGFL  L+RLNV++TRAK  L ++G   TL
Sbjct: 520 AEVDTVDAFQGRQKDCVIVTCVRANSIQGSIGFLASLQRLNVTITRAKYSLFILGHLRTL 579

Query: 629 SSHETYKKMIEFFKEKGCFIE 649
             ++ + ++I+  +++G  I+
Sbjct: 580 MENQHWNQLIQDAQKRGAIIK 600


>gi|11429653 KIAA0625 protein [Homo sapiens]
           Length = 916
           
 Score =  148 bits (369), Expect = 2e-34
 Identities = 143/561 (25%), Positives = 255/561 (44%), Gaps = 115/561 (20%)

Query: 165 VPFDKSLNRSQRKAISKALGS-------EDFFLVHGPFGTGKTRTLV----ELIRQEVKR 213
           + + +  N  Q+KAI  A              L+HGP GTGK++T+V     L+ +  ++
Sbjct: 167 IAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRK 226

Query: 214 G------------NKVLATAESNVAVDNLVERL----------------SRSGIKIVRIG 245
           G            N+VL  A SN AVD L++++                +   I +VR+G
Sbjct: 227 GHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLG 286

Query: 246 HPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGLSDEEI 305
                 K ++   L + +     +   +EL    Q++ ++++              D ++
Sbjct: 287 P----EKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKE------------FLDYQL 330

Query: 306 IKLAERKRGARGLSARLIMEMAEWI-KLNRQVQKAFDDARKLEERIARD---IIREADVV 361
            +L+ ++   RG       E+ E I K++++ Q+     ++++ R  +    II E+ ++
Sbjct: 331 DELSRQRALCRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHII 390

Query: 362 LTTNSSAALEVVDYD-------TYDVAIIDEATQSTIPSILIPL-NKVERFVLAGDHKQL 413
             T S++   +++          +   I+DEA QS     L PL ++  + +L GD KQL
Sbjct: 391 CCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQL 450

Query: 414 PPTILSLEAQE--------------LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPS 459
           PPT++S++AQE              L   +   +I R P     L VQYRM+  I  FPS
Sbjct: 451 PPTVISMKAQEYGYDQSMMARFCRLLEENVEHNMISRLPILQ--LTVQYRMHPDICLFPS 508

Query: 460 KEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRG 519
              Y   +  +     I           +  W     P    +  D          +RR 
Sbjct: 509 NYVYNRNLKTNRQTEAIRC---------SSDW-----PFQPYLVFDVGDGS-----ERRD 549

Query: 520 SESRENPLEAEIVAKIV----DKLLSIGVKPEWIGVITPYDDQRDLISMKVPED------ 569
           ++S  N  E ++V +I+    DK   +  +   IG+IT Y  Q+ +I   + ++      
Sbjct: 550 NDSYINVQEIKLVMEIIKLIKDKRKDVSFRN--IGIITHYKAQKTMIQKDLDKEFDRKGP 607

Query: 570 VEVKTVDGYQGREKEVIILSLVRSNKL-GEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL 628
            EV TVD +QGR+K+ +I++ VR+N + G IGFL  L+RLNV++TRAK  L ++G   TL
Sbjct: 608 AEVDTVDAFQGRQKDCVIVTCVRANSIQGSIGFLASLQRLNVTITRAKYSLFILGHLRTL 667

Query: 629 SSHETYKKMIEFFKEKGCFIE 649
             ++ + ++I+  +++G  I+
Sbjct: 668 MENQHWNQLIQDAQKRGAIIK 688


>gb|AAG20303.1| (AE005104) DNA binding protein eukaryotic-like; Dbp [Halobacterium
           sp. NRC-1]
           Length = 751
           
 Score =  147 bits (367), Expect = 4e-34
 Identities = 105/309 (33%), Positives = 163/309 (51%), Gaps = 45/309 (14%)

Query: 344 RKLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVER 403
           R +++   +  +  ADVV  T + AA    D + +D+A++DEATQ++  +  I +N  + 
Sbjct: 442 RVVDDHYRQRGVDAADVVAATTNGAA--TFDQNAFDLAVVDEATQASRAATAIAVNAADT 499

Query: 404 FVLAGDHKQLPP-TILSLEAQELSRTLFEGLIERYPWKSEMLVV-QYRMNERIMEFPSKE 461
            VLAGDH+QLPP  +    A E+  +LFE LI+RY     +L+  QYRM++ I  FP++ 
Sbjct: 500 LVLAGDHRQLPPYGVREGGAGEMRPSLFETLIDRYGDDVAVLLARQYRMHDAIAGFPNEA 559

Query: 462 FYGGK-----IIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQ 516
           FYGG+     + AD +V G+                        +  +D +  E    R 
Sbjct: 560 FYGGRLETAAVAADRAVDGLP----------------------PVAVVDVAGQE---RRD 594

Query: 517 RRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE------DV 570
            RG+  R N  EA +VA  VD +   GV+P  +GVI  Y D    I   + +       +
Sbjct: 595 ERGASVR-NAAEASVVADRVDTIRRAGVEPGDLGVIAAYSDHVSAIRGVLADRGLDRPAL 653

Query: 571 EVKTVDGYQGREKEVIILSLVRSNKLGEIGFLK----DLRRLNVSLTRAKRKLIVVGDSS 626
            V TVD +QG E++ +++S  RSN   + GFL+      RRLNV+LTRA+R L +VGD +
Sbjct: 654 TVDTVDSFQGGERDAVVVSFARSNDAHDAGFLEHPAAGPRRLNVALTRARRHLSLVGDWA 713

Query: 627 TLSSHETYK 635
           TL+   +++
Sbjct: 714 TLTDPASHR 722


>gb|AAF23837.1|AC007234_9 (AC007234) F1E22.14 [Arabidopsis thaliana]
           Length = 1076
           
 Score =  142 bits (354), Expect = 1e-32
 Identities = 110/352 (31%), Positives = 180/352 (50%), Gaps = 31/352 (8%)

Query: 314 GARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREADVVLTTNSSAALEVV 373
           G+   S++ +    +++KL R + + F      +  + +++      +L + +S +  + 
Sbjct: 500 GSDRFSSQHVTVEDDYLKLLRSIPEIFPLPAVSDRHLIKELCLGHACLLFSTASCSARLY 559

Query: 374 DYDTYDVAIIDEATQ--STIPSILIPLNKVERFVLAGDHKQLPPTILSLEAQE--LSRTL 429
                 + +IDEA Q      SI + L  +   +L GD +QLP  + S  A E    R+L
Sbjct: 560 TGTPIQLLVIDEAAQLKECESSIPMQLPGLRHLILVGDERQLPAMVESQIALEAGFGRSL 619

Query: 430 FEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPND 489
           FE L      K  ML +QYRM+  I  FP+KE YG KI+   +VR    R+  +   P +
Sbjct: 620 FERLA-LLGHKKYMLNIQYRMHCSISSFPNKELYGKKILDAPTVRQ---RNYTKQYLPGE 675

Query: 490 SWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEW- 548
            +G    P + I     + A  + E       S +N +E  +VA I+  LL +  K +  
Sbjct: 676 MYG----PYSFI-----NIAYGREEYGEGEGRSLKNNVEVVVVAAIIANLLQVSEKTKTR 726

Query: 549 --IGVITPYDDQRDLISMKVPE----------DVEVKTVDGYQGREKEVIILSLVRSNKL 596
             +GVI+PY  Q   I  K+ E           + ++TVDG+QG E+++II+S VRSN +
Sbjct: 727 INVGVISPYKAQVIAIQEKIQETSIGDAGGLFSLRIRTVDGFQGGEEDIIIVSTVRSNGV 786

Query: 597 GEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL-SSHETYKKMIEFFKEKGCF 647
           G +GFL + RR NV LTRA+  L ++G+ +TL +S   ++ +I+  KE+GCF
Sbjct: 787 GRVGFLGNRRRTNVLLTRARFCLWILGNEATLMNSKSVWRNLIQDAKERGCF 838


>gb|AAG09081.1|AC026237_2 (AC026237) Similar to tRNA-splicing endonuclease positive effector
            SEN1 [Arabidopsis thaliana]
            Length = 2142
            
 Score =  138 bits (345), Expect = 1e-31
 Identities = 138/513 (26%), Positives = 222/513 (42%), Gaps = 97/513 (18%)

Query: 216  KVLATAESNVAVDNLVERLSRSGIK----------IVRIGHPSRVSKHLHETTLAYLITQ 265
            +VL  A+SN AVD LV R+S  GI           +VR+G+   V  +     L  L+ Q
Sbjct: 1306 RVLICAQSNAAVDELVSRISSLGIYGRDGKMFKPYLVRVGNAKTVHSNSMPFFLDTLVDQ 1365

Query: 266  HELYGELR------------------ELRVIGQSLA-----------EKRDTYTKPTPKF 296
                  +R                   L  +   +            E  D   KP  + 
Sbjct: 1366 RLAEERMRINESKSNKGADSSALLRSNLEKVVDQITHFEAKRANINQESLDAKDKPENEH 1425

Query: 297  RRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIR 356
                 D +++  AE     R L  +      +   +  Q +KA  + R L++++ + I++
Sbjct: 1426 HNKDDDGKLMSDAELGIRLRRLYEQKRKIYKDLSAVQAQERKANYEMRTLKQKLRKSILK 1485

Query: 357  EADVVLTTNSSAALEVVDY----------------DTYDVAIIDEATQSTIPSILIPLNK 400
            EA +V+TT S    ++                   + +D  +IDEA Q+  P+ LIPL  
Sbjct: 1486 EAQIVVTTLSGCGGDLYSVCAESLAAHKFGSPSEDNLFDAVVIDEAAQALEPATLIPLQL 1545

Query: 401  VE----RFVLAGDHKQLPPTILSLEAQEL--SRTLFEGLIERYPWKSEMLVVQYRMNERI 454
            ++    + ++ GD KQLP T+LS  A +     ++FE L +R  +   ML  QYRM+  I
Sbjct: 1546 LKSRGTKCIMVGDPKQLPATVLSNVASKFLYECSMFERL-QRAGYPILMLTQQYRMHPEI 1604

Query: 455  MEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWE 514
              FPS  FY  K++      G+ +         N   G         VF D    +   E
Sbjct: 1605 CRFPSMHFYDNKLL-----NGVDMSSKSAPFHENHHLGPY-------VFYDIVDGQ---E 1649

Query: 515  RQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEW----IGVITPYDDQRDLISMK----- 565
             +   S S  N  EAE   +++ +        E+    IG+ITPY  Q  ++  +     
Sbjct: 1650 HRSGDSSSVCNEQEAEAAVQLL-RFFKKRYPSEFVAGRIGIITPYKRQLAVLRSRFTGAF 1708

Query: 566  ---VPEDVEVKTVDGYQGREKEVIILSLVRSN-------KLGEIGFLKDLRRLNVSLTRA 615
               V  D+E+ TVDG+QG+E ++++LS VR+            IGF+ D+RR+NV+LTRA
Sbjct: 1709 GAQVTADMEMNTVDGFQGKEVDILVLSTVRATHSAPDGVNQSRIGFVADVRRMNVALTRA 1768

Query: 616  KRKLIVVGDSSTLSSHETYKKMIEFFKEKGCFI 648
            K  L V+G++ TL     +  +++  KE+   I
Sbjct: 1769 KLSLWVLGNTRTLQRDHNWGALVKDAKEREVII 1801


>gb|AAF50482.1| (AE003556) CG7504 gene product [Drosophila melanogaster]
            Length = 1417
            
 Score =  137 bits (342), Expect = 3e-31
 Identities = 136/485 (28%), Positives = 226/485 (46%), Gaps = 75/485 (15%)

Query: 190  LVHGPFGTGKTRTLVELIRQEVKRGN-------KVLATAESNVAVDNLVERL-------S 235
            L+ GP GTGK+R + EL  Q +  GN       K+L  A SN AVD++V  L       +
Sbjct: 938  LIQGPPGTGKSRVISELCLQTLY-GNAAKTLDRKILICAHSNTAVDHIVGLLGSVLRVMN 996

Query: 236  RSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPK 295
            R    ++R G   ++S +    +  + +  H    + ++L+ + +  AE          K
Sbjct: 997  RDQFHLLRFGMHEKMSHY----SRPFSLEAHFNKAKEQKLQRVSKENAEI-------LKK 1045

Query: 296  FRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDD--ARKLEERIARD 353
                L DE    + + K      S  L+ ++ +  K  + +         ++ E  I+  
Sbjct: 1046 QHNDLKDE----IQQLKEKTNLTSTYLLQQLQQKEKKLQLISNQLSPPLTQREEFEISHM 1101

Query: 354  IIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLN-KVERFVLAGDHKQ 412
             +  A+++ TT SS        D +D+ I+DEATQ T P  L+P+   +   VL GD +Q
Sbjct: 1102 CVTRANIICTTLSSCVKLANYVDFFDICIVDEATQCTEPWTLLPMRFGLTHMVLVGDMQQ 1161

Query: 413  LPPTILSLEAQE--LSRTLFE-------------GLIERYPWKSEMLVVQYRMNERIMEF 457
            LP  +LS +A +  LS ++F+             G       K   L  QYRM+  I  +
Sbjct: 1162 LPAVVLSKKAIDFGLSNSMFDRIQRSLQTQLDKPGSYHLMHTKLFKLSTQYRMHPEICRW 1221

Query: 458  PSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQR 517
            P++ FY  ++I  E            + SP   +  I    N+    D++ A+NK     
Sbjct: 1222 PNQYFYEDQLINAECT--------ARFASPLIPYCVI----NLKYTCDSNGAQNK----- 1264

Query: 518  RGSESRENPLEAEIVAKIVDKL-LSIGVKPEWIGVITPYDDQRDLISMKVPEDVEV--KT 574
                S  N  EA  VAK++ ++   +  K    G+I+PY +Q   +S  +P  + +  +T
Sbjct: 1265 ----SISNNEEARFVAKLLTEMDKHMPSKRFSYGLISPYQNQCYALSQVIPSHMNITPQT 1320

Query: 575  VDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETY 634
            VD YQG EK+VII+S  R+      GFL + +RLNV+LTR +R L++ G+   L S E +
Sbjct: 1321 VDSYQGLEKDVIIISNARTR---GCGFLTNYQRLNVALTRPRRCLVICGNFEDLKSVEMW 1377

Query: 635  KKMIE 639
            + +++
Sbjct: 1378 RNLLD 1382


>pir||T28788 hypothetical protein C41D11.7 - Caenorhabditis elegans
           >gi|2105497|gb|AAC48142.1| (AF003740) similar to
           mammalian DNA-binding proteins SMUBP-2 [Caenorhabditis
           elegans]
           Length = 633
           
 Score =  136 bits (338), Expect = 1e-30
 Identities = 156/594 (26%), Positives = 259/594 (43%), Gaps = 110/594 (18%)

Query: 95  VVEKGKRFIVVALETVPEWALRDVRIDLYANDITFRRWLENLN----TIKKAGKRALRFY 150
           ++E  K+F    LE V +W +  V ++   N     ++    N    T++   +  +   
Sbjct: 1   MIEADKKF----LELVKKWGVLSVGLNQKQNTNPVYQYTLEDNPESLTLQDVLESHMTDP 56

Query: 151 LGLDEPSQGEEVNFVPFDKSLNRSQRKAISKALG-SEDFFLVHGPFGTGKTRTLVELIRQ 209
           + L+     E+   +PF    N  QR AI  AL  +     + GP GTGKT TL  L+ +
Sbjct: 57  IELNSFDSMEKEAGIPFS---NEKQRTAIKMALNENRKLVCIQGPPGTGKTFTLTLLLCR 113

Query: 210 EVKRGNKVLATAESNVAVDNL----VERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQ 265
            +++  +V+  A +  A+ N+     + L R GIK+             HE  L      
Sbjct: 114 LIQQKKQVVVLAPTREALANIRMMTKKTLKRMGIKV-------------HEHAL------ 154

Query: 266 HELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARG-LSARLIM 324
                             E RD   K     R  ++ EE+  L  RK    G ++  ++ 
Sbjct: 155 --------------MDTNEYRDVINKSD---RALMAAEEVRDL--RKAFDNGEITENVLD 195

Query: 325 EMAEWIKLNRQVQKAFDDARKLEERIARDIIREADVVLTTNSSAALE-VVDYDTYD--VA 381
           EM + I +NR           +   +  ++I    V   T  ++ ++ V+ +  +D  + 
Sbjct: 196 EMRQSI-INR-----------VRNEVGAEVIGNVRVAFATIGASFVDFVMKHKKFDPCLC 243

Query: 382 IIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIER--- 436
           IIDEA Q         + K++R V+AGD KQLP  + + EA+   L  ++ + ++E+   
Sbjct: 244 IIDEAAQVMEAQTWPAVYKMKRIVMAGDPKQLPALVFTDEAKAFGLQNSVMDRILEKKNN 303

Query: 437 YPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILN 496
           + W   ML  QYR N +I  + +  FY  ++  D      +L  ++  Q       K  N
Sbjct: 304 FSWI--MLENQYRSNAKIATWSNTCFYHNQLKTDVKCHEYSLHTILNPQPK-----KFRN 356

Query: 497 PENVIVFIDTSKAENKWER---------------QRRGSESRENPLEAEIVAKIVDKLLS 541
             + +V IDTS   +  +R               + +   S  N  EA+I      +LL 
Sbjct: 357 LFDPLVLIDTSLERDVEKRLETYEHAVFDTNSINKTKQGFSYANLAEAKIAIGHYQRLLK 416

Query: 542 IGVKPEWIGVITPYDDQRDLISMKVPE-----------DVEVKTVDGYQGREKEVIILSL 590
            GV+P  I +ITPY  Q  L++  + E              + TVD  QG+E EV+I ++
Sbjct: 417 YGVQPSDIAIITPYKGQTSLVTKLMEEFGAETGYTDFVQTTIGTVDSVQGKEYEVVIFTM 476

Query: 591 VRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL--SSHETYKKMIEFFK 642
           VRSN    +GF+ +LRRLNV +TRAKR  + +G+   L  S  +  +K+ + FK
Sbjct: 477 VRSNPRKTMGFVSELRRLNVVITRAKRHFMFIGNGYLLAESKKDEIRKLYDCFK 530


>dbj|BAB11057.1| (AB015478) contains similarity to nonsense-mediated mRNA decay
           trans-acting factor~gene_id:MSG15.19 [Arabidopsis
           thaliana]
           Length = 676
           
 Score =  135 bits (337), Expect = 1e-30
 Identities = 102/340 (30%), Positives = 177/340 (52%), Gaps = 39/340 (11%)

Query: 330 IKLNRQVQKAFDDARKLE-ERIARDIIREADVVLTTNSSAA-LEVVDYDTYDVAIIDEAT 387
           +K  R + K F+    LE E I +  ++ AD++L T S AA + V      ++ ++DEA 
Sbjct: 314 LKALRLLPKRFEIPDMLENEDIRKFCLQNADIILCTASGAAEMNVERTGNVELLVVDEAA 373

Query: 388 Q----STIPSILIPLNKVERFVLAGDHKQLPPTILS--LEAQELSRTLFEGLIERYPWKS 441
           Q     ++ ++ +P   +   +L GD  QLP  + +   E  +  R+LFE L+       
Sbjct: 374 QLKECESVAALQLP--GLRHAILIGDEFQLPAMVHNEMCEKAKFGRSLFERLV-LLGHNK 430

Query: 442 EMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVI 501
            +L VQYRM+  I  FP+KEFYGG+I   E+V+    +      +  DS+          
Sbjct: 431 HLLDVQYRMHPSISRFPNKEFYGGRIKDAENVKESIYQKRFLKGNMFDSFS--------- 481

Query: 502 VFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEW---IGVITPYDDQ 558
            FI+  + + ++        S +N +E  ++++I+  L  +  +      +GV++PY  Q
Sbjct: 482 -FINVGRGKEEFG----DGHSPKNMVEVAVISEIISNLYKVSCERRMKVSVGVVSPYKGQ 536

Query: 559 RDLISMKVPED----------VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRL 608
              I  K+ +           + V++VDG+QG E+++II+S VRSN  G++GFL + +R 
Sbjct: 537 MRAIQEKIGDKYSSLSGQQFTLNVRSVDGFQGGEEDIIIISTVRSNGNGKVGFLNNRQRA 596

Query: 609 NVSLTRAKRKLIVVGDSSTLS-SHETYKKMIEFFKEKGCF 647
           NV+LTRA+  L V+G+ +TL+ S   +  +I   + +GCF
Sbjct: 597 NVALTRARHCLWVIGNETTLALSGSIWATLISESRTRGCF 636


>gb|AAF57908.1| (AE003804) CG6967 gene product [Drosophila melanogaster]
           Length = 765
           
 Score =  134 bits (335), Expect = 2e-30
 Identities = 139/509 (27%), Positives = 231/509 (45%), Gaps = 103/509 (20%)

Query: 172 NRSQRKAISKALG---SEDFFLVHGPFGTGKTRTLVELIRQE--VKRGNKVLATAESNVA 226
           N  Q +A+ + +    ++  +++ GP GTGKT T+VE I Q    +  +++L TA SN A
Sbjct: 252 NAEQLEAVQRIVAGPSTQGPYILFGPPGTGKTTTIVEAILQLRLQQPQSRILVTAGSNSA 311

Query: 227 VDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKR 286
            D +  +L         I    R+ +H  +  L      H+L      +RV  +S+ EK 
Sbjct: 312 CDTIALKLCEY------IESNIRLQEHFAQQKLPE--PDHQL------IRVYSRSIYEK- 356

Query: 287 DTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKL 346
                                      G   + + L+              K  + ++ +
Sbjct: 357 ---------------------------GFASVPSLLL--------------KNSNCSKSI 375

Query: 347 EERIARDIIREADVVLTTNSSAALEVVD----YDTYDVAIIDEATQSTIPSILIPLNKVE 402
            + I    I +  +++ T  + A  V D    Y+ +    IDEA  ST P  LI +  ++
Sbjct: 376 YDHIKASRIVKYGIIVATLCTVARLVTDTLGRYNFFTHIFIDEAGASTEPEALIGIMGIK 435

Query: 403 R-----FVLAGDHKQLPPTILSLEAQEL--SRTLFEGLIERYPWKSE-----------ML 444
           +      +L+GDHKQL   I S  A  L  SR+L E L++   +KS+            L
Sbjct: 436 QTADCHVILSGDHKQLGAVIKSNRAASLGLSRSLMERLLQSDCYKSDENGNYDRNRQMRL 495

Query: 445 VVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFI 504
              YR + +I+   ++ +Y G++ A      + L           +W  + NP+  I+F 
Sbjct: 496 CRNYRSHPQIVRLFNELYYNGELKAQAPAMDVNLAA---------NWSVLTNPQFPIIFQ 546

Query: 505 DTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVK-PEWIGVITPYDDQRDLIS 563
            T    N+     + S S  N LEAE++   V +L++  V   E +G++ PY  Q  L++
Sbjct: 547 ATHGVTNR----EQNSTSSYNNLEAEVICWYVKRLINDRVVGQEDVGIVAPYTAQGKLVT 602

Query: 564 MKVPE----DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKL 619
             +      +VEV +V+ YQGREK +II SLV+S     +GF+ + RR+NV L+RAK  L
Sbjct: 603 KLLQSKGYPNVEVGSVETYQGREKTIIIASLVKS--FTNMGFMCNPRRVNVLLSRAKALL 660

Query: 620 IVVGDSSTLSSHETYKKMIEFFKEKGCFI 648
           I+VG+  TL  H  +K +I   K+ G ++
Sbjct: 661 ILVGNPVTLRHHSDFKFVINECKKHGTYL 689


>gi|6321958 DNA replication helicase; Dna2p [Saccharomyces cerevisiae]
            >gi|731738|sp|P38859|DNA2_YEAST DNA REPLICATION HELICASE
            DNA2 >gi|626832|pir||S48904 probable purine
            nucleotide-binding protein YHR164c - yeast
            (Saccharomyces cerevisiae) >gi|458906|gb|AAB68010.1|
            (U00027) Dna2p: DNA replication helicase [Saccharomyces
            cerevisiae]
            Length = 1522
            
 Score =  134 bits (334), Expect = 3e-30
 Identities = 99/309 (32%), Positives = 163/309 (52%), Gaps = 21/309 (6%)

Query: 355  IREADVVLTT--NSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQ 412
            I    VV TT    +  L  ++   +D  I+DEA+Q ++P  L PL    RF++ GDH Q
Sbjct: 1155 INSTSVVATTCLGINDILFTLNEKDFDYVILDEASQISMPVALGPLRYGNRFIMVGDHYQ 1214

Query: 413  LPPTILSLEAQ--ELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKI--- 467
            LPP + +  A+   L  +LF+   E++P     L +QYRM   I+   +   Y  K+   
Sbjct: 1215 LPPLVKNDAARLGGLEESLFKTFCEKHPESVAELTLQYRMCGDIVTLSNFLIYDNKLKCG 1274

Query: 468  ---IADESVRGITLRDLVEYQSPNDS---WGK-ILNPENVIVFIDTSKAENKWERQRRGS 520
               +  +S+       L  Y++ + +   W + IL P   +VF++     +  E+  +  
Sbjct: 1275 NNEVFAQSLELPMPEALSRYRNESANSKQWLEDILEPTRKVVFLNYDNCPDIIEQSEK-- 1332

Query: 521  ESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQ----RDLISMKVPEDVEVKTVD 576
            ++  N  EAE+  + V+ +L  GV  E IGV+T Y  Q    + + +  V + +E+ T D
Sbjct: 1333 DNITNHGEAELTLQCVEGMLLSGVPCEDIGVMTLYRAQLRLLKKIFNKNVYDGLEILTAD 1392

Query: 577  GYQGREKEVIILSLVRSN-KLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYK 635
             +QGR+K+ II+S+VR N +L     LK+LRR+NV++TRAK KLI++G  ST+ S    K
Sbjct: 1393 QFQGRDKKCIIISMVRRNSQLNGGALLKELRRVNVAMTRAKSKLIIIGSKSTIGSVPEIK 1452

Query: 636  KMIEFFKEK 644
              +   +E+
Sbjct: 1453 SFVNLLEER 1461


>dbj|BAB11372.1| (AB017068) contains similarity to nonsense-mediated mRNA decay
           trans-acting factors~gene_id:MJG14.22 [Arabidopsis
           thaliana]
           Length = 880
           
 Score =  131 bits (327), Expect = 2e-29
 Identities = 102/351 (29%), Positives = 177/351 (50%), Gaps = 48/351 (13%)

Query: 330 IKLNRQVQKAFDDARKLE-ERIARDIIREADVVLTTNSSAA-LEVVDYDTYDVAIIDEAT 387
           +K  R + K F+    LE E I +  ++ AD++L T S AA + V      ++ ++DEA 
Sbjct: 509 LKALRLLPKRFEIPDMLENEDIRKFCLQNADIILCTASGAAEMNVERTGNVELLVVDEAA 568

Query: 388 Q----STIPSILIPLNKVERFVLAGDHKQLPPTILS-----------LEAQELSRTLFEG 432
           Q     ++ ++ +P   +   +L GD  QLP  + +            E  +  R+LFE 
Sbjct: 569 QLKECESVAALQLP--GLRHAILIGDEFQLPAMVHNEYCNMGIMWQMCEKAKFGRSLFER 626

Query: 433 LIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWG 492
           L+        +L VQYRM+  I  FP+KEFYGG+I   E+V+    +      +   S+ 
Sbjct: 627 LV-LLGHNKHLLDVQYRMHPSISRFPNKEFYGGRIKDAENVKESIYQKRFLQGNMFGSFS 685

Query: 493 KILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEW---I 549
                     FI+  + + ++        S +N +E  +V++I+  L  +  +      +
Sbjct: 686 ----------FINVGRGKEEFG----DGHSPKNMVEVAVVSEIISNLFKVSCERRMKVSV 731

Query: 550 GVITPYDDQRDLISMKVPED----------VEVKTVDGYQGREKEVIILSLVRSNKLGEI 599
           GV++PY  Q   I  K+ +           + V++VDG+QG E+++II+S VRSN  G++
Sbjct: 732 GVVSPYKGQMRAIQEKIGDKYSSLSGQQFTLNVRSVDGFQGGEEDIIIISTVRSNSNGKV 791

Query: 600 GFLKDLRRLNVSLTRAKRKLIVVGDSSTLS-SHETYKKMIEFFKEKGCFIE 649
           GFL + +R NV+LTRA+  L V+G+ +TL+ S   +  +I   + +GCF +
Sbjct: 792 GFLNNRQRANVALTRARHCLWVIGNETTLALSGSIWATLISESRTRGCFYD 842


>gb|AAB67523.1| (U21094) Sen1p [Saccharomyces cerevisiae]
           Length = 757
           
 Score =  131 bits (326), Expect = 3e-29
 Identities = 112/366 (30%), Positives = 182/366 (49%), Gaps = 39/366 (10%)

Query: 300 LSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIAR-DIIREA 358
           +S E+I KL  + R      +++I E+       R+        R L+ R A+  I+  +
Sbjct: 33  MSTEDISKLQLKIREL----SKIINELGRDRDEMREKNSVNYRNRDLDRRNAQAHILAVS 88

Query: 359 DVVLTTNSSAALEVVDYD--TYDVAIIDEATQSTIPSILIPLNKV-ERFVLAGDHKQLPP 415
           D++ +T S +A +V+      +D  IIDEA Q T  S +IPL    +R ++ GD  QLPP
Sbjct: 89  DIICSTLSGSAHDVLATMGIKFDTVIIDEACQCTELSSIIPLRYGGKRCIMVGDPNQLPP 148

Query: 416 TILSLEAQELSRTLFEGLIERYPWKSE--MLVVQYRMNERIMEFPSKEFYGGKIIADESV 473
           T+LS  A        + L  R    S   +L VQYRM+  I +FPS EFY G++     +
Sbjct: 149 TVLSGAASNFKYN--QSLFVRMEKNSSPYLLDVQYRMHPSISKFPSSEFYQGRLKDGPGM 206

Query: 474 RGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVA 533
             +  R           W + L P     F D        + Q   + S  N  E  +  
Sbjct: 207 DILNKRP----------WHQ-LEPLAPYKFFDIISGR---QEQNAKTMSYTNMEEIRVAI 252

Query: 534 KIVDKLL-SIGVKPEW---IGVITPYDDQRDLISMK--------VPEDVEVKTVDGYQGR 581
           ++VD L      K ++   IG+I+PY +Q   +  +        + + ++  T+DG+QG+
Sbjct: 253 ELVDYLFRKFDNKIDFTGKIGIISPYREQMQKMRKEFARYFGGMINKSIDFNTIDGFQGQ 312

Query: 582 EKEVIILSLVRSNKL-GEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEF 640
           EKE+I++S VR++     +GFLKD RR+NV+LTRAK  + V+G   +L+  + ++ +IE 
Sbjct: 313 EKEIILISCVRADDTKSSVGFLKDFRRMNVALTRAKTSIWVLGHQRSLAKSKLWRDLIED 372

Query: 641 FKEKGC 646
            K++ C
Sbjct: 373 AKDRSC 378


>pir||T22132 hypothetical protein F43G6.1a - Caenorhabditis elegans
            >gi|3877086|emb|CAA90399.1| (Z50070) similar to DNA
            binding protein~cDNA EST EMBL:Z14942 comes from this
            gene~cDNA EST yk46a12.3 comes from this gene~cDNA EST
            yk27h9.5 comes from this gene~cDNA EST yk46a12.5 comes
            from this gene~cDNA EST yk130a10.5 comes from this
            gene~cDNA EST y>
            Length = 1105
            
 Score =  131 bits (326), Expect = 3e-29
 Identities = 100/285 (35%), Positives = 154/285 (53%), Gaps = 13/285 (4%)

Query: 352  RDIIREADVVLTTNSSAALEVV-DYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDH 410
            R +++   +V  T      E++  Y  +DV I+DEA+    P +L  L    +FVL GD 
Sbjct: 793  RKVMKTTPIVACTCHHVPRELLFSYRHFDVVIVDEASMVLEPLLLPVLATSNKFVLVGDC 852

Query: 411  KQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKII 468
            KQL P ++S +A++     +  E L + +P     L  QYRMN  I    SK FY  ++I
Sbjct: 853  KQLTPLVVSRKAKQEGAGISTMEKLQQSHPGVVVSLTSQYRMNREISVLSSKLFYENRLI 912

Query: 469  -ADESVRGITLRDLVEY----QSPNDSWGKILNPE--NVIVFIDT-SKAENKWERQRRGS 520
              +ESV   +L    +Y       +D   K L+ +  +  VF+DT S   +K + +    
Sbjct: 913  CGNESVSRSSLDRTGDYIVAMDDGSDHIRKALSGDIKDSCVFLDTQSTINSKMQCEDGEG 972

Query: 521  ESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLI-SMKVPEDVEVKTVDGYQ 579
                N  EA++++++  + +  GVKP  IGV++ Y  Q D I  +   +++EV T+D YQ
Sbjct: 973  GGMCNDGEAKLISELCQQFVMSGVKPHEIGVMSAYRRQVDHIRGILNSDELEVNTIDSYQ 1032

Query: 580  GREKEVIILSLV-RSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVG 623
            GREK VII SL   +N   +   LKD RR+NV+LTRA++KL+VVG
Sbjct: 1033 GREKRVIIWSLTWTNNSTKKSELLKDERRVNVALTRARQKLVVVG 1077


>pir||T22138 hypothetical protein F43G6.1b - Caenorhabditis elegans
            >gi|5824500|emb|CAB54253.1| (Z50070) cDNA EST yk592a5.5
            comes from this gene~cDNA EST yk653b11.5 comes from this
            gene [Caenorhabditis elegans]
            Length = 1069
            
 Score =  131 bits (326), Expect = 3e-29
 Identities = 100/285 (35%), Positives = 154/285 (53%), Gaps = 13/285 (4%)

Query: 352  RDIIREADVVLTTNSSAALEVV-DYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDH 410
            R +++   +V  T      E++  Y  +DV I+DEA+    P +L  L    +FVL GD 
Sbjct: 757  RKVMKTTPIVACTCHHVPRELLFSYRHFDVVIVDEASMVLEPLLLPVLATSNKFVLVGDC 816

Query: 411  KQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKII 468
            KQL P ++S +A++     +  E L + +P     L  QYRMN  I    SK FY  ++I
Sbjct: 817  KQLTPLVVSRKAKQEGAGISTMEKLQQSHPGVVVSLTSQYRMNREISVLSSKLFYENRLI 876

Query: 469  -ADESVRGITLRDLVEY----QSPNDSWGKILNPE--NVIVFIDT-SKAENKWERQRRGS 520
              +ESV   +L    +Y       +D   K L+ +  +  VF+DT S   +K + +    
Sbjct: 877  CGNESVSRSSLDRTGDYIVAMDDGSDHIRKALSGDIKDSCVFLDTQSTINSKMQCEDGEG 936

Query: 521  ESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLI-SMKVPEDVEVKTVDGYQ 579
                N  EA++++++  + +  GVKP  IGV++ Y  Q D I  +   +++EV T+D YQ
Sbjct: 937  GGMCNDGEAKLISELCQQFVMSGVKPHEIGVMSAYRRQVDHIRGILNSDELEVNTIDSYQ 996

Query: 580  GREKEVIILSLV-RSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVG 623
            GREK VII SL   +N   +   LKD RR+NV+LTRA++KL+VVG
Sbjct: 997  GREKRVIIWSLTWTNNSTKKSELLKDERRVNVALTRARQKLVVVG 1041


>gi|11499542 DNA helicase, putative [Archaeoglobus fulgidus]
           >gi|7483284|pir||G69494 DNA helicase homolog -
           Archaeoglobus fulgidus >gi|2648582|gb|AAB89295.1|
           (AE000968) DNA helicase, putative [Archaeoglobus
           fulgidus]
           Length = 453
           
 Score =  130 bits (324), Expect = 4e-29
 Identities = 109/306 (35%), Positives = 156/306 (50%), Gaps = 30/306 (9%)

Query: 349 RIARDIIREADVVLTTN----SSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERF 404
           RI  D+IR+  +V+ +       +AL+  D+DT    IIDEA+ + I + L+ L K E+ 
Sbjct: 164 RIQNDMIRKGKIVVGSTILKGMMSALKNYDFDT---VIIDEASNTCISTALLALEKAEKA 220

Query: 405 VLAGDHKQLPPTILSLEAQELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYG 464
           V+ GD  QLPP       +    + +  LI  Y  K+  L   YR N +I EF ++  YG
Sbjct: 221 VVVGDPYQLPPVYEVGGHKAAKFSAYNFLINIY-GKNLWLRRHYRSNAKIAEFAARHVYG 279

Query: 465 GKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRE 524
              I DE  R I +      +    +  ++ +PE  +VFID +  E      RR   S+ 
Sbjct: 280 FLEI-DEKCRRIKI------EPCKTTIPEVGDPEKPLVFIDCNGVE------RREGRSKV 326

Query: 525 NPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE---DVEVKTVDGYQGR 581
           N  EAE+VA I ++L    V  E +GVITPY  Q +LI   + E    VEV TV  YQGR
Sbjct: 327 NEEEAEVVAMIAEELAEC-VGEENVGVITPYVKQAELIRGILSEFGVMVEVSTVHSYQGR 385

Query: 582 EKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETY--KKMIE 639
           EK+V+I S+  +   G   F  + R  NV+LTRA++K I VG+S  L        + M+ 
Sbjct: 386 EKDVVIYSITAT---GNPYFASEKRLFNVALTRARKKFIAVGNSKALEGKNLLLTRFMVA 442

Query: 640 FFKEKG 645
             KE G
Sbjct: 443 AIKEGG 448


>dbj|BAB11370.1| (AB017068) contains similarity to nonsense-mediated mRNA decay
           trans-acting factors~gene_id:MJG14.20 [Arabidopsis
           thaliana]
           Length = 701
           
 Score =  127 bits (316), Expect = 4e-28
 Identities = 98/339 (28%), Positives = 174/339 (50%), Gaps = 34/339 (10%)

Query: 330 IKLNRQVQKAFDDARKLEERIARDI-IREADVVLTTNSSAA-LEVVDYDTYDVAIIDEAT 387
           +++ R + + F+ +  LE    +   ++ AD++  T S AA +  +   + D+ ++DEA 
Sbjct: 340 LQILRLLPERFEVSDMLENNDTKTFCLQNADIIFCTASGAADMNPIRTGSVDLLVVDEAA 399

Query: 388 Q-STIPSIL-IPLNKVERFVLAGDHKQLPPTILS--LEAQELSRTLFEGLIERYPWKSEM 443
           Q     S+  + L+ +   VL GD  QLP  + +   E  +  R+LFE L+        +
Sbjct: 400 QLKECESVAALQLSGLRHAVLIGDELQLPAMVHNEICEKAKFGRSLFERLV-LLGHNKHL 458

Query: 444 LVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVF 503
           L VQYRM+  I  FP+KEFYGG+I    +V+    +      +   S+           F
Sbjct: 459 LNVQYRMHPSISRFPNKEFYGGRIKDAANVQESIYQKRFLQGNMFGSFS----------F 508

Query: 504 IDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEW---IGVITPYDDQRD 560
           I+  + E ++        S +N +E  ++++I+  L  +  +      +GV++PY  Q  
Sbjct: 509 INVGRGEEEFG----DGHSPKNMVEVAVISEIISNLFKVSSERRIKMSVGVVSPYKGQVR 564

Query: 561 LISMKVPED---------VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVS 611
            I  +             + V++VDG+QG E+++II+S VRSN  G++GFL + +R NV+
Sbjct: 565 AIQERTTNKYSSLSGLFTLNVRSVDGFQGGEEDIIIISTVRSNGNGKVGFLNNRQRANVA 624

Query: 612 LTRAKRKLIVVGDSSTLS-SHETYKKMIEFFKEKGCFIE 649
           LTRA+  L V+G+ +TL+ S  ++ K+I   +  GCF +
Sbjct: 625 LTRARHCLWVIGNETTLALSGSSWAKLISESRTLGCFYD 663


>pir||T00740 hypothetical protein F22O13.35 - Arabidopsis thaliana
           Length = 814
           
 Score =  125 bits (312), Expect = 1e-27
 Identities = 90/258 (34%), Positives = 127/258 (48%), Gaps = 49/258 (18%)

Query: 378 YDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIE 435
           +DV IIDEA Q  +P  + PL     FVL GDH QLPP + S EA+E  +  +LF  L E
Sbjct: 550 FDVCIIDEAGQIALPVSIGPLLFASTFVLVGDHYQLPPLVQSTEARENGMGISLFRRLSE 609

Query: 436 RYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKIL 495
            +P    +L  QYRM   IME  +   YG ++    +                       
Sbjct: 610 AHPQAISVLQNQYRMCRGIMELSNALIYGDRLCCGSA----------------------- 646

Query: 496 NPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPY 555
              +  + + TS + + W                  + KIV++L++ GV  + IG+ITPY
Sbjct: 647 EVADATLVLSTSSSTSPW------------------LKKIVEELVNNGVDSKDIGIITPY 688

Query: 556 DDQRDLISMKVP-EDVEVKTVDGYQGREKEVIILSLVRSN---KLGEIGFLKDLRRLNVS 611
           + Q  LI   +P   VE+ T+D YQGR+K+ I++S VRS    +      L D  R+NV+
Sbjct: 689 NSQASLIQHAIPTTPVEIHTIDKYQGRDKDCILVSFVRSREKPRSSASSLLGDWHRINVA 748

Query: 612 LTRAKRKLIVVGDSSTLS 629
           LTRA  KLI+VG   TLS
Sbjct: 749 LTRA--KLIMVGSQRTLS 764


 Score = 77.6 bits (188), Expect = 4e-13
 Identities = 41/127 (32%), Positives = 77/127 (60%), Gaps = 2/127 (1%)

Query: 157 SQGEEVNFVPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNK 216
           SQ   ++++  +KSLN  QR+AI K L ++D+ L+ G  GTGKT T+V  ++  + RG+ 
Sbjct: 410 SQDPAISYIWSEKSLNNDQRQAILKILTAKDYALILGMPGTGKTSTMVHAVKALLIRGSS 469

Query: 217 VLATAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLA--YLITQHELYGELRE 274
           +L  + +N AVDNL+ +L   GI+ +RIG    V + + E+  +   + +  ++  +L +
Sbjct: 470 ILLASYTNSAVDNLLIKLKAQGIEFLRIGRDEAVHEEVRESCFSAMNMCSVEDIKKKLDQ 529

Query: 275 LRVIGQS 281
           ++V+  +
Sbjct: 530 VKVVAST 536


>dbj|BAB08973.1| (AB024026) gb|AAD48967.1~gene_id:K15O15.6~strong similarity to
           unknown protein [Arabidopsis thaliana]
           Length = 536
           
 Score =  122 bits (304), Expect = 1e-26
 Identities = 94/305 (30%), Positives = 158/305 (50%), Gaps = 39/305 (12%)

Query: 367 SAALEVVDYDT--YDVAIIDEATQ----STIPSILIPLNKVERFVLAGDHKQLPPTILS- 419
           S A E+ +  T   +V ++DEA Q     ++ ++ +P   +   +L GD  QLP  + + 
Sbjct: 233 SGAAEINEERTGNIEVLVVDEAAQLKECESVAALQLP--GLRHAILIGDEFQLPAMVHND 290

Query: 420 -LEAQELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITL 478
             E  +  R+LFE L+     K  +L VQYRM+  I  FP KEFYGG+I    +V+    
Sbjct: 291 QCEKAKFGRSLFERLV-LLGHKKHLLDVQYRMHPSISRFPYKEFYGGRIKDAANVQESIY 349

Query: 479 RDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDK 538
           +      +   S+           FI+  + + ++       +S +N +E  +V++I+  
Sbjct: 350 QKRFLQGNMFGSFS----------FINVGRGKEEFG----DGDSPKNMVEVAVVSEIISN 395

Query: 539 LLSIGVKPEW---IGVITPYDDQRDLISMKVPED----------VEVKTVDGYQGREKEV 585
           L  +  + +    +GVITPY  Q   I  ++ +           V V++VDG+QG E+++
Sbjct: 396 LFKVSRERKMKMSVGVITPYKGQVRAIQERIRDKYSSLSGELFTVNVRSVDGFQGGEEDI 455

Query: 586 IILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLS-SHETYKKMIEFFKEK 644
           II+S VRSN  G++GFL + +R NV+LTRA+  L V+G+ STL+ S   +  +I   K +
Sbjct: 456 IIISTVRSNSNGKVGFLSNRQRANVALTRARHCLWVIGNESTLARSGSIWANLISDSKRR 515

Query: 645 GCFIE 649
            CF +
Sbjct: 516 KCFYD 520


>dbj|BAB11373.1| (AB017068) contains similarity to DNA helicase~gene_id:MJG14.23
           [Arabidopsis thaliana]
           Length = 834
           
 Score =  122 bits (303), Expect = 1e-26
 Identities = 95/324 (29%), Positives = 164/324 (50%), Gaps = 39/324 (12%)

Query: 348 ERIARDIIREADVVLTTNSSAA-LEVVDYDTYDVAIIDEATQ----STIPSILIPLNKVE 402
           E I +  ++ AD++  T SS A +      + D+ ++DE  Q     ++ ++ +P   + 
Sbjct: 492 EDIRKFCLQNADIIFCTASSVANINPARIGSVDLLVVDETAQLKECESVAALQLP--GLC 549

Query: 403 RFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSK 460
             +L GD  QLP  + + E  +    R+LFE L+        +L VQYRM+  I  FP+K
Sbjct: 550 HALLIGDEYQLPAMVHNEECDKAKFGRSLFERLV-LIGHSKHLLNVQYRMHPSISRFPNK 608

Query: 461 EFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGS 520
           EFYGG+I    +V+          +S  +      N      FI+  + + ++       
Sbjct: 609 EFYGGRITDAANVQ----------ESIYEKRFLQGNMFGTFSFINVGRGKEEFG----DG 654

Query: 521 ESRENPLEAEIVAKIVDKLLSIGVKPEW---IGVITPYDDQRDLISMKVPED-------- 569
            S +N +E  +++KI+  L  +  + +    +GVI+PY  Q   I  +V +         
Sbjct: 655 HSPKNMVEVAVISKIISNLFKVSSQRKQKMSVGVISPYKGQVRAIQERVGDKYNSLSVDQ 714

Query: 570 ---VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSS 626
              + V++VDG+QG E +VII+S VR N  G +GFL + +R NV+LTRA+  L V+G+ +
Sbjct: 715 LFTLNVQSVDGFQGGEVDVIIISTVRCNVNGNVGFLSNRQRANVALTRARHCLWVIGNGT 774

Query: 627 TLS-SHETYKKMIEFFKEKGCFIE 649
           TL+ S   + ++I   + +GCF +
Sbjct: 775 TLALSGSIWAELISESRTRGCFYD 798


>gb|AAD48967.1|AF147263_9 (AF147263) contains similarity to nonsense-mediated mRNA decay
           trans-acting factors [Arabidopsis thaliana]
           >gi|7267314|emb|CAB81096.1| (AL161503) contains
           similarity to nonsense-mediated mRNA decay trans-acting
           factors~similarity to~Contains Prokaryotic membrane
           lipoprotein lipid attachment site AA120-130 [Arabidopsis
           thaliana]
           Length = 660
           
 Score =  122 bits (302), Expect = 2e-26
 Identities = 101/315 (32%), Positives = 160/315 (50%), Gaps = 34/315 (10%)

Query: 334 RQVQKAFD-DARKLEERIARDIIREADVVLTTNSSAALEVVDY-DTYDVAIIDEATQ-ST 390
           R + K F+  A  ++E I    ++ A ++  T S AA    +   + D+ ++DEA Q   
Sbjct: 356 RLLSKRFEIPALLMKEDIRTFCLQNAHIIFCTASGAAEMTAERAGSIDMLVVDEAAQLKE 415

Query: 391 IPSIL-IPLNKVERFVLAGDHKQLPPTILS--LEAQELSRTLFEGLIERYPWKSEMLVVQ 447
             S+  + L  +   VL GD  QLP  + S   E  +  R+LFE L +    K  +L VQ
Sbjct: 416 CESVAALQLQGLHHAVLIGDELQLPAMVQSEVCEKAKFVRSLFERL-DSLGHKKHLLNVQ 474

Query: 448 YRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTS 507
           YRM+  I  FP+ EFYGGKI   E V+  T +      +   S+           FI+  
Sbjct: 475 YRMHPSISLFPNMEFYGGKISDAEIVKESTYQKRFLQGNMFGSFS----------FINVG 524

Query: 508 KAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEW---IGVITPYDDQRDLISM 564
             + ++        S +N +E  +V++I+  LL +  + +    +GVI+PY  Q   I  
Sbjct: 525 LGKEEFG----DGHSPKNMVEIAVVSEILTNLLKVSSETKTKMSVGVISPYKAQVSAIQE 580

Query: 565 KVPED----------VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTR 614
           ++ +           + V++VDG+QG E+++II+S VRSN  G IGFL + +R NV+LTR
Sbjct: 581 RIGDKYTSVSDNLFTLNVRSVDGFQGGEEDIIIISTVRSNCNGNIGFLSNRQRANVALTR 640

Query: 615 AKRKLIVVGDSSTLS 629
           A+  L V+G+  TLS
Sbjct: 641 ARHCLWVIGNERTLS 655


>gb|AAF23836.1|AC007234_8 (AC007234) F1E22.16 [Arabidopsis thaliana]
           Length = 1075
           
 Score =  122 bits (302), Expect = 2e-26
 Identities = 103/326 (31%), Positives = 161/326 (48%), Gaps = 58/326 (17%)

Query: 363 TTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNK--VERFVLAGDHKQLPPTILS- 419
           T +SSA L +       + +IDEA Q       IPL    ++  +L GD KQLP  I S 
Sbjct: 540 TASSSARLHMSS--PIQLLVIDEAAQLKECESAIPLQLRGLQHAILIGDEKQLPAMIKSN 597

Query: 420 --------------------------LEAQELSRTLFEGLIERYPWKSEMLVVQYRMNER 453
                                         +L R+LFE L+       ++L +QYRM+  
Sbjct: 598 VGSLILTNYTHIHSLLFAYLISYVQIASEADLGRSLFERLV-LLGHNKQLLNMQYRMHPS 656

Query: 454 IMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKW 513
           I  FP++EFY  KI+   SVR   LR   +   P   +G          FI+ +    ++
Sbjct: 657 ISIFPNREFYDMKILDAPSVR---LRSYEKKFLPEKMYGP-------YSFINIAYGREQF 706

Query: 514 ERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPE---WIGVITPYDDQRDLISMKVPE-- 568
                   S +N +E  +VA+IV KL S+  K      +GVI+PY  Q   I  ++ E  
Sbjct: 707 GE----GYSSKNLVEVSVVAEIVSKLYSVSRKTGRTISVGVISPYKAQVFAIQERIGEKY 762

Query: 569 ------DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVV 622
                  V V++VDG+QG E+++II+S VRSN  G IGFL + +R NV+LTRA+  L ++
Sbjct: 763 NTEGTFTVSVRSVDGFQGGEEDIIIISTVRSNGNGAIGFLSNQQRTNVALTRARYCLWIL 822

Query: 623 GDSSTLSSHET-YKKMIEFFKEKGCF 647
           G+ +TL+++ + ++++++  K + CF
Sbjct: 823 GNEATLTNNRSVWRQLVDDAKARNCF 848


>gb|AAF46543.1| (AE003449) CG2990 gene product [Drosophila melanogaster]
            Length = 1119
            
 Score =  120 bits (299), Expect = 4e-26
 Identities = 98/313 (31%), Positives = 153/313 (48%), Gaps = 50/313 (15%)

Query: 378  YDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIE 435
            +D  I+DEATQ   P++L PL    +FVL GD +QLPP + S EA++     TLF+ L  
Sbjct: 784  FDYCIVDEATQVLQPTVLRPLIHCSKFVLVGDPEQLPPIVRSKEARQRGADETLFQRLDS 843

Query: 436  RYPWKSEMLVVQYRMNERIMEFPSKEFYGGKI-IADESVRGITLRDLVEYQSPNDSWGK- 493
                 + +L +QYRMN+ I    ++  YGG +  A + V G      VE  +    W + 
Sbjct: 844  EKA--TAVLSLQYRMNKTITRLANELTYGGDLKCASDEVSGARFE--VELLNEAPRWVQR 899

Query: 494  --ILNPENVIVFIDT--------------------------SKAENKWERQRRGSESR-- 523
                + E  +  I+T                          S +E+K E ++  S+ R  
Sbjct: 900  ALTTHLEQAVTLINTGDCLERCQEFVYASQRLVDTCSSIEQSFSEDKDEIRKLTSKKRVS 959

Query: 524  --ENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDL---ISMKVPEDVEVKTVDGY 578
               N  EA IV  ++  LL  G +   IGVI PY  Q +L   ++ K+  D+E  TVD +
Sbjct: 960  KYTNYCEAGIVMHLLRYLLKSGYEASRIGVIAPYRAQVELFKKLASKLDTDLECNTVDQF 1019

Query: 579  QGREKEVIILSLVRSN-------KLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSH 631
            QGR+K +II S  ++        +  E   L+D RRL V++TRAK KLI++GD   L  +
Sbjct: 1020 QGRDKNLIIYSCSKTGGDFSDMERSREAEILEDQRRLTVAITRAKNKLILLGDIKCLEQY 1079

Query: 632  ETYKKMIEFFKEK 644
              ++++ +   ++
Sbjct: 1080 GPFRQLFKHIPDR 1092


 Score = 71.0 bits (171), Expect = 4e-11
 Identities = 78/270 (28%), Positives = 123/270 (44%), Gaps = 28/270 (10%)

Query: 36  ERERLGRAILNLNGKIIGEELGYFLVKYGRNREIKTE-----------ISVGDLVVISKR 84
           ERE+ G AI +L   + G+E+     +Y +  E+  E             +G+ VVIS  
Sbjct: 501 EREKEGIAIRHLK-LVKGQEVILEEGRYRQTLELGEEADPSRDLSLSGFDLGEYVVISST 559

Query: 85  DPLKSDLLGTVVEKGKRFIVVALET--VPEWALRDVRIDLYANDITFRRWLENLNTIKKA 142
             L +   G +V    R + + LE      ++     ID + +         NL  +   
Sbjct: 560 SRL-AVAAGFIVSIEARRLDLRLERDLSQRYSEETFIIDKHDSQSFATFNFTNLGMLLSE 618

Query: 143 GKR--ALRFYLGLDEPSQGEEV-------NFVPFDKSLNRSQRKAISKALGSEDFFLVHG 193
           G+R   LR  +   +P +  +V          P   +LN+ Q+ A  +AL +    L+ G
Sbjct: 619 GERFQELRDIIVAKKPPEQHKVLPKIILTKGAPILLNLNKVQQNAALRALTTSSHLLIKG 678

Query: 194 PFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKH 253
             GTGKT+TLV L+R     G  VL TA+++ AVDNL+ RL   G+ ++R+G  SR+ K 
Sbjct: 679 LPGTGKTQTLVALVRLLHLLGKSVLITAQTHSAVDNLIMRLLPFGLPMMRLGSGSRIHKQ 738

Query: 254 LHETTLAYLI----TQHELYGELRELRVIG 279
           L E +   L     T  EL   L +  ++G
Sbjct: 739 LEEISEERLTKDCKTVEELEKALGQPSIVG 768


>gb|AAF56255.1| (AE003746) CG6204 gene product [Drosophila melanogaster]
           Length = 903
           
 Score =  115 bits (284), Expect = 2e-24
 Identities = 134/492 (27%), Positives = 227/492 (45%), Gaps = 75/492 (15%)

Query: 165 VPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNK-----VLA 219
           +P D  LN SQ+ A  +AL  E F ++ GP GTGKT   V+L+   ++         ++ 
Sbjct: 444 LPEDLHLNESQKTAFKEALCRE-FSIIQGPPGTGKTHLSVQLVNSLIQNAKALGTGPIIV 502

Query: 220 TAESNVAVDNLVERLSRSGIKIVRIGHPSR---VSKHLHETTLAYLITQHELYGELRELR 276
              +N ++D  + ++SR   +I+R G+ SR   +SK    TT+   +    L       R
Sbjct: 503 LTYTNNSLDKFLVKISRYTQEILRFGNQSRDPQISKFNLSTTIKPELVPPRLK------R 556

Query: 277 VIGQSLAEKRDTYTKPTPKFRRGLSDEEIIK--LAERKRGARGLSARLIMEMAEWIKLNR 334
           +      E ++ +      +      EE  +  LA +++         + ++AE I+  R
Sbjct: 557 IWWLVNCEYKEKFRNLQGLYANFDGSEESYQDTLAAQEK---------LNQVAERIETLR 607

Query: 335 QVQKAFDDARKLEERIARDIIREADVVLTTNSSAALEVVDYDTYD--VAIIDEATQSTIP 392
            V + F             + RE D++  T + AA     +        + +EA +    
Sbjct: 608 MVFQFF-------------LAREKDLLAMTTTCAARHNFLFRLLQSKCVLFEEAAEIQEA 654

Query: 393 SILIPLNK-VERFVLAGDHKQLPPTILSLEAQELSRTLFEGLIER-YPWKSEMLVVQYRM 450
            I+  L    E  +L GDHKQL P   S +  ++S  LFE LI    P+    L +QYRM
Sbjct: 655 HIVACLTPHTEHVILVGDHKQLQPFSGSRKVPQIS--LFERLIVAGLPFSR--LNLQYRM 710

Query: 451 NERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAE 510
              I E      Y  +++  ESV+        EY+         L  +N + F+  ++ E
Sbjct: 711 RSCISELLVPSIYD-ELLCSESVK--------EYEDIR------LMSKN-LYFVQHNQPE 754

Query: 511 NKWERQRRGSESRENPLEAEIVAKIVDKLLSIG-VKPEWIGVITPYDDQRDLISMKVPED 569
           +       G     N  EA ++AK+ + L+     K   I +++PY+ Q + I   +P++
Sbjct: 755 HCMSDMSIG-----NLYEAGVLAKLTEFLIQKAQYKHSDIVILSPYNGQIECIKNALPQN 809

Query: 570 ----VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDS 625
               V+V +VD +QG E  +++LSLVRSN  G IGFL+   R+ V+L+RA+  L +VG+ 
Sbjct: 810 YRSTVQVASVDSFQGLEANIVLLSLVRSNISGRIGFLRQANRVCVALSRARWALYIVGNV 869

Query: 626 STLSSHETYKKM 637
           + L   +T+ K+
Sbjct: 870 TILK--DTFPKI 879


>gb|AAA58611.1| (M64979) glial factor-1 [Homo sapiens]
           Length = 376
           
 Score =  115 bits (284), Expect = 2e-24
 Identities = 56/136 (41%), Positives = 91/136 (66%), Gaps = 3/136 (2%)

Query: 513 WERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE---D 569
           +E +    +S+ NP E  +V+  +  L+  GV    I V++PY+ Q DL+   +     +
Sbjct: 9   FELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRHPE 68

Query: 570 VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLS 629
           +E+K+VDG+QGREKE +ILS VRSN+ GE+GFL + RR+NV++TRA+R + V+ DS T++
Sbjct: 69  LEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTVN 128

Query: 630 SHETYKKMIEFFKEKG 645
           +H   K ++E+F + G
Sbjct: 129 NHAFLKTLVEYFTQHG 144


>pir||A70369 hypothetical protein aq_791 - Aquifex aeolicus
           >gi|2983352|gb|AAC06940.1| (AE000707) putative protein
           [Aquifex aeolicus]
           Length = 163
           
 Score =  112 bits (278), Expect = 1e-23
 Identities = 65/138 (47%), Positives = 92/138 (66%), Gaps = 4/138 (2%)

Query: 8   NRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEEL-GYFLVKYGRN 66
           N  K L+++ER A+ E    E++ LSG ERE+ GRAILNL  K +G  L G +LV+Y R 
Sbjct: 14  NYFKRLIDLERRAQTELHLKEIKTLSGKEREKRGRAILNLRAKFLGRGLGGVYLVRYSRP 73

Query: 67  REI-KTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVAL-ETVPEWAL-RDVRIDLY 123
           + + KTEIS GD+V++SK  P   ++ GTV EK   ++VVA  +  P +AL +DVRIDL+
Sbjct: 74  QGLPKTEISTGDIVLVSKGKPTVKEVQGTVAEKTNYYLVVAFRDKPPPYALGKDVRIDLF 133

Query: 124 ANDITFRRWLENLNTIKK 141
           +N+ITF+R  E L   K+
Sbjct: 134 SNEITFKRMEEALKNFKE 151


>pir||D64588 probable DNA helicase - Helicobacter pylori (strain 26695)
           Length = 274
           
 Score =  109 bits (270), Expect = 9e-23
 Identities = 76/284 (26%), Positives = 147/284 (51%), Gaps = 44/284 (15%)

Query: 378 YDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTI----------------LSLE 421
           +DV IIDE  ++T P ILIP  + ++ +L GDH QLPP+I                 +++
Sbjct: 3   FDVTIIDETGRATAPEILIPALRTKKLILIGDHNQLPPSIDRYLLEQLESDDIQNLDAID 62

Query: 422 AQELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDL 481
            Q L  + FE L +  P  ++ ++ ++RM   I    S+ FY       E ++   +++ 
Sbjct: 63  RQLLEESFFENLYKYIPESNKAMLNEFRMPASIGSLVSQLFY------KEKLKNGVIKNT 116

Query: 482 VEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLS 541
            ++           +P+N+I +I+    E + + ++  S ++    +   + + ++++L+
Sbjct: 117 SQF----------YDPKNIIRWIN---VEGEHQLEKTSSYNKNQVQKIIELLEQINRVLN 163

Query: 542 IGVKPEWIGVITPYDDQRDLISMKVP-------EDVEVKTVDGYQGREKEVIILSLVRSN 594
                + IG+ITPY+ Q+  +  +V        +++++ TVD +QG + ++II S V++ 
Sbjct: 164 QRKIRKTIGIITPYNAQKRCLRSEVEKYGFKNFDELKIDTVDAFQGEKADIIIYSTVKT- 222

Query: 595 KLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMI 638
             G + FL D +RLNV+++RAK  LI VG  S   +  + +K I
Sbjct: 223 -YGNLSFLIDSKRLNVAISRAKENLIFVGKKSFFENLRSDEKNI 265


>pir||T41111 hypothetical ATP binding protein - fission yeast
           (Schizosaccharomyces pombe) >gi|3581879|emb|CAA20777.1|
           (AL031540) hypothetical protein [Schizosaccharomyces
           pombe]
           Length = 1015
           
 Score =  101 bits (250), Expect = 2e-20
 Identities = 84/291 (28%), Positives = 146/291 (49%), Gaps = 38/291 (13%)

Query: 354 IIREADVV--LTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIP--LNKVERFVLAGD 409
           ++R A+V+   TT  +   ++++     +  I+EA    +   +IP     +E+ VL GD
Sbjct: 679 LLRGANVIGMTTTGLNKYRDILERINPKICFIEEAAD-VLEGPIIPAVFPSLEQLVLIGD 737

Query: 410 HKQLPPTILSLEAQE----LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGG 465
           HKQL P   +   ++    LS ++FE L+E    +   L +Q RM+ +I    S  +   
Sbjct: 738 HKQLRPGCSTYALRQDPFNLSISMFERLVEN-DMEYTRLTMQRRMHPQIRRLVSSVY--- 793

Query: 466 KIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESREN 525
                     ++  ++ +Y       G+I        F+  S+ E+       G  S+ N
Sbjct: 794 --------EDLSDYEITKYWPSIPGMGEIRR-----FFLTHSRIEDN-----DGFASKIN 835

Query: 526 PLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPED-------VEVKTVDGY 578
             EA+++ +    L++ GV+P+ I  +T Y  Q+DLI   + E        ++V TVDGY
Sbjct: 836 LFEAQMLVQFAVYLINNGVEPQKITCLTFYAAQKDLIERLLSESLNREKHFIKVATVDGY 895

Query: 579 QGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLS 629
           QG E +V++LSLVR+N   E+GFL    R+ VSL+RA+R L + G++  ++
Sbjct: 896 QGEENDVVLLSLVRNNDRTEVGFLSSPHRVCVSLSRARRGLFIFGNAQLVA 946


>gb|AAF79736.1|AC005106_17 (AC005106) T25N20.11 [Arabidopsis thaliana]
           Length = 1048
           
 Score = 99.1 bits (243), Expect = 1e-19
 Identities = 100/335 (29%), Positives = 164/335 (48%), Gaps = 60/335 (17%)

Query: 360 VVLTTNSSAAL---EVVDYDTYDVAIIDEATQSTIPSILIPLNKV----ERFVLAGDHKQ 412
           +V++T  SA+L   E V+   +   ++DEA Q++ P  +I ++ +       VLAGD +Q
Sbjct: 564 LVVSTYMSASLLNAEGVNRGHFTHILLDEAGQASEPENMIAVSNLCLTETVVVLAGDPRQ 623

Query: 413 LPPTILSLEAQELS--RTLFEGLIE---------RYPWKSEMLVVQYRMNERIMEFPSKE 461
           L P I S +A+ L   ++  E L E          Y  K   LV  YR +  I++ PSK 
Sbjct: 624 LGPVIYSRDAESLGLGKSYLERLFECDYYCEGDENYVTK---LVKNYRCHPEILDLPSKL 680

Query: 462 FYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSE 521
           FY G+++A +      L  L            + N E  +VF      +     +R G+ 
Sbjct: 681 FYDGELVASKEDTDSVLASL----------NFLPNKEFPMVFYGIQGCD-----EREGNN 725

Query: 522 -SRENPLEAEIVAKIVDKLLSIG-VKPEWIGVITPYDDQ----RDLISMKVPEDVEVKTV 575
            S  N +E   V + + +L +   V+ E IGVITPY  Q    ++++      +V+V +V
Sbjct: 726 PSWFNRIEISKVIETIKRLTANDCVQEEDIGVITPYRQQVMKIKEVLDRLDMTEVKVGSV 785

Query: 576 DGYQGREKEVIILSLVRSN-KLGE------IGFLKDLRRLNVSLTRAKRKLIVVGDSSTL 628
           + +QG+EK+VII+S VRS  K  E      +GFL + RR NV++TRA   L+++G+   +
Sbjct: 786 EQFQGQEKQVIIISTVRSTIKHNEFDRAYCLGFLSNPRRFNVAITRAISLLVIIGNPHII 845

Query: 629 SSHETYKKM----IEFFKEKGC-------FIEFPF 652
                + K+    ++    +GC       F+E PF
Sbjct: 846 CKDMNWNKLLWRCVDNNAYQGCGLPEQEEFVEEPF 880


>gb|AAF58307.1| (AE003816) CG6701 gene product [Drosophila melanogaster]
           Length = 1194
           
 Score = 96.3 bits (236), Expect = 9e-19
 Identities = 86/295 (29%), Positives = 145/295 (49%), Gaps = 40/295 (13%)

Query: 376 DTYDVAIIDEATQSTIPSILI----PLNKVERFVLAGDHKQLPPTILSLEAQE--LSRTL 429
           + Y    +DEA  ST   +L+     L+     +L+GDHKQL P + S  A E  L  TL
Sbjct: 618 NVYTHVFVDEAAASTEAEVLMGITCTLSPTLNLILSGDHKQLGPVLQSQRANEWGLGLTL 677

Query: 430 FEGLIERYPWKSE-----------MLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITL 478
           FE L++R  ++ E            L+  +R +  I+   +  +Y G +   E+   I  
Sbjct: 678 FERLLQRKCYQVEEDGSYNASVQTRLIRNFRSHPEIVSLYNNMYYEGHL-RTEAPMEIVC 736

Query: 479 RDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDK 538
           R    +  PN ++  + +     VF  T   ++        S S  N  E ++V   V  
Sbjct: 737 RFHNWFYLPNATFPIMFHS----VFGTTMNTKS--------SVSLCNNKEIDVVMDYVKD 784

Query: 539 LLSIGVKPEW-----IGVITPYDDQ----RDLISMKVPEDVEVKTVDGYQGREKEVIILS 589
           L+  G+  E      IG+I+PY +Q    ++ ++M+    ++  +V+ +QG+EK VII+S
Sbjct: 785 LMYFGLNGEKLLQTDIGIISPYKNQYQRIQEQLNMRNWSQIDCGSVELFQGKEKHVIIVS 844

Query: 590 LVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEK 644
            VRS    ++GFL + RRLNV L+R    LI++G+  TLS +  ++ +IE  + +
Sbjct: 845 FVRSFT-PKLGFLNNERRLNVLLSRPISLLILIGNPRTLSQNSDFQHIIEMCRNR 898


>dbj|BAA92642.1| (AB037825) KIAA1404 protein [Homo sapiens]
            Length = 1925
            
 Score = 95.2 bits (233), Expect = 2e-18
 Identities = 88/313 (28%), Positives = 149/313 (47%), Gaps = 35/313 (11%)

Query: 344  RKLEERIARD--IIREADVVLTTNSSAAL--EVVDYDTYDVAIIDEATQSTIPSILIPLN 399
            R  E R+  D  I+++A VV  T + AA   +++      + I++EA +      +  L+
Sbjct: 969  RMAELRLQEDLHILKDAQVVGMTTTGAAKYRQILQKVEPRIVIVEEAAEVLEAHTIATLS 1028

Query: 400  KV-ERFVLAGDHKQLPPTILSLEAQE---LSRTLFEGLIE-RYPWKSEMLVVQYRMNERI 454
            K  +  +L GDH+QL P+    +  +   L  +LFE L++   P+    L  Q+RM   I
Sbjct: 1029 KACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFERLVKVNIPFVR--LNYQHRMCPEI 1086

Query: 455  MEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWE 514
                +   Y               +DL  + S    + KI    + + F++     N  E
Sbjct: 1087 ARLLTPHIY---------------QDLENHPSVL-KYEKIKGVSSNLFFVE----HNFPE 1126

Query: 515  RQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQ----RDLISMKVPEDV 570
            ++ +  +S +N  EA  V ++    L     P  I ++T Y  Q    R L+  K    V
Sbjct: 1127 QEIQEGKSHQNQHEAHFVVELCKYFLCQEYLPSQITILTTYTGQLFCLRKLMPAKTFAGV 1186

Query: 571  EVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSS 630
             V  VD YQG E ++I+LSLVRSN+ G++GFL+   R+ V+L+RAK+ +  +G+   L+ 
Sbjct: 1187 RVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQISNRICVALSRAKKGMYCIGNMQMLAK 1246

Query: 631  HETYKKMIEFFKE 643
               + K+I   +E
Sbjct: 1247 VPLWSKIIHTLRE 1259


>dbj|BAB14696.1| (AK023836) unnamed protein product [Homo sapiens]
           Length = 1137
           
 Score = 95.2 bits (233), Expect = 2e-18
 Identities = 88/313 (28%), Positives = 149/313 (47%), Gaps = 35/313 (11%)

Query: 344 RKLEERIARD--IIREADVVLTTNSSAAL--EVVDYDTYDVAIIDEATQSTIPSILIPLN 399
           R  E R+  D  I+++A VV  T + AA   +++      + I++EA +      +  L+
Sbjct: 254 RMAELRLQEDLHILKDAQVVGMTTTGAAKYRQILQKVEPRIVIVEEAAEVLEAHTIATLS 313

Query: 400 KV-ERFVLAGDHKQLPPTILSLEAQE---LSRTLFEGLIE-RYPWKSEMLVVQYRMNERI 454
           K  +  +L GDH+QL P+    +  +   L  +LFE L++   P+    L  Q+RM   I
Sbjct: 314 KACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFERLVKVNIPFVR--LNYQHRMCPEI 371

Query: 455 MEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWE 514
               +   Y               +DL  + S    + KI    + + F++     N  E
Sbjct: 372 ARLLTPHIY---------------QDLENHPSVL-KYEKIKGVSSNLFFVE----HNFPE 411

Query: 515 RQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQ----RDLISMKVPEDV 570
           ++ +  +S +N  EA  V ++    L     P  I ++T Y  Q    R L+  K    V
Sbjct: 412 QEIQEGKSHQNQHEAHFVVELCKYFLCQEYLPSQITILTTYTGQLFCLRKLMPAKTFAGV 471

Query: 571 EVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSS 630
            V  VD YQG E ++I+LSLVRSN+ G++GFL+   R+ V+L+RAK+ +  +G+   L+ 
Sbjct: 472 RVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQISNRICVALSRAKKGMYCIGNMQMLAK 531

Query: 631 HETYKKMIEFFKE 643
              + K+I   +E
Sbjct: 532 VPLWSKIIHTLRE 544


>pir||T42668 hypothetical protein DKFZp434B0717.1 - human (fragment)
           >gi|6453506|emb|CAB61391.1| (AL133068) hypothetical
           protein [Homo sapiens]
           Length = 678
           
 Score = 94.8 bits (232), Expect = 3e-18
 Identities = 122/444 (27%), Positives = 193/444 (42%), Gaps = 79/444 (17%)

Query: 262 LITQHELYGELRELRVI--GQSLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLS 319
           L  +  L G+ R L  I  G     K  T  +   +    L D  I+  A     A  + 
Sbjct: 218 LAVKRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHFALPDSRILVCAPSNSAADLVC 277

Query: 320 ARL----IMEMAEWIKLNR--QVQKAFDDARKLEERIARDIIREAD--VVLTTNSSAALE 371
            RL    ++  A  +++N   + ++   DA K   R   DI + +   +++TT SS+ L 
Sbjct: 278 LRLHESKVLRPATMVRVNATCRFEEIVIDAVKPYCRDGEDIWKASRFRIIITTCSSSGLF 337

Query: 372 V---VDYDTYDVAIIDEATQSTIPSILIPLNKVE----RFVLAGDHKQLPPTILSLEAQE 424
               V    +    +DEA Q++ P  LIPL  +     + VLAGD  QL P I S  A  
Sbjct: 338 YQIGVRVGHFTHVFVDEAGQASEPECLIPLGLMSDISGQIVLAGDPMQLGPVIKSRLAMA 397

Query: 425 --LSRTLFEGLIERYPWKSE----------------MLVVQYRMNERIMEFPSKEFYGGK 466
             L+ +  E L+ R  ++ +                 LV  YR +E ++  PS+ FY  +
Sbjct: 398 YGLNVSFLERLMSRPAYQRDENAFGACGAHNPLLVTKLVKNYRSHEALLMLPSRLFYHRE 457

Query: 467 --IIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRE 524
             + AD +V    L            W K+      ++F              RGSE+RE
Sbjct: 458 LEVCADPTVVTSLL-----------GWEKLPKKGFPLIFHGV-----------RGSEARE 495

Query: 525 -------NPLEAEIVAK---IVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE----DV 570
                  NP EA  V +   ++   +S  V    IGVITPY  Q + I + +      D+
Sbjct: 496 GKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQVEKIRILLRNVDLMDI 555

Query: 571 EVKTVDGYQGREKEVIILSLVRSNK------LGEIGFLKDLRRLNVSLTRAKRKLIVVGD 624
           +V +V+ +QG+E  VII+S VRSN+         +GFL + +R NV++TR K  LIV+G+
Sbjct: 556 KVGSVEEFQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGN 615

Query: 625 SSTLSSHETYKKMIEFFKEKGCFI 648
              L     +  ++E+    G ++
Sbjct: 616 PHVLVRDPCFGALLEYSITNGVYM 639


>pir||T47242 DNA helicase homolog - fission yeast (Schizosaccharomyces pombe)
           (fragment) >gi|3329511|gb|AAC39502.1| (AF075169) DNA
           helicase homolog [Schizosaccharomyces pombe]
           Length = 191
           
 Score = 93.2 bits (228), Expect = 8e-18
 Identities = 63/189 (33%), Positives = 97/189 (50%), Gaps = 14/189 (7%)

Query: 378 YDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIE 435
           +D  IIDEA+Q  +P  L PL   E+FVL GDH QLPP + +    +  LS +LF+ L E
Sbjct: 6   FDYCIIDEASQIPLPICLGPLQLAEKFVLVGDHYQLPPLVKNSRTSKDGLSLSLFKLLSE 65

Query: 436 RYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADES--------VRGITLRDLVEYQSP 487
           ++P     L +QYRMNE I    S+  YGG ++            +    L D +   S 
Sbjct: 66  KHPEAVTTLRLQYRMNEDINSLSSELIYGGNLVCGSKTISQKKLILPKAHLSDGLPDSSS 125

Query: 488 NDSW-GKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKP 546
           +  W  K++NP + ++F +T   ++    + + +   EN  EA ++ + V   L  GVK 
Sbjct: 126 SLHWVNKLINPSHSVIFFNT---DDILGVESKTNNILENHTEAFLIEQAVSSFLERGVKQ 182

Query: 547 EWIGVITPY 555
             IG+I+ Y
Sbjct: 183 SSIGIISIY 191


>gb|AAF47775.1| (AE003478) CG11513 gene product [Drosophila melanogaster]
            Length = 1274
            
 Score = 92.1 bits (225), Expect = 2e-17
 Identities = 83/297 (27%), Positives = 143/297 (47%), Gaps = 47/297 (15%)

Query: 382  IIDEATQSTIPSILIPL----NKVERFVLAGDHKQLPPTILSLEAQEL--SRTLFEGLIE 435
            + DEA Q T P  ++P+     K  + VL+GD +QL   + S  A ++  S +  E L+E
Sbjct: 946  LFDEAGQCTEPETMVPIVMLTKKRSQVVLSGDPRQLQSIVTSRIASKMGFSISFLERLLE 1005

Query: 436  RYPWKSEM----------------LVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLR 479
            R P++ ++                L+  YR    IM   S+ FY  ++I   S +     
Sbjct: 1006 RSPYRKDLQRFPESSGYNPLVLTKLLYNYRALPSIMSIYSRLFYDDELIPVLSEKDSRES 1065

Query: 480  DLVE-----YQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAK 534
             L+      ++S  D       P+    F      EN   RQ   S S  NP E   V  
Sbjct: 1066 RLLSKLRCVFESEKDI------PQAHGTFFYGIIGEN---RQNNDSPSWFNPQEVREVFL 1116

Query: 535  IVDKLLSIGVKPEWIGVITPYDDQRDLI-SMKVPEDV---EVKTVDGYQGREKEVIILSL 590
            +   L    V  + IG+ITPY  Q  ++ SM +  DV   ++ +V+ +QG+E+++I++S 
Sbjct: 1117 MTIALYRANVTADQIGIITPYQKQVKMLRSMFIGTDVVMPKIGSVEEFQGQERDIILIST 1176

Query: 591  VRSNK-------LGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEF 640
            VRS++          +GF++  +RLNV+++RA+  +I+ G+   L+  E ++++I F
Sbjct: 1177 VRSSEEILRMDARFSLGFVRCSKRLNVAVSRARAMMIIFGNPHLLAVDECWRQLILF 1233


>gi|6678920 Moloney leukemia virus 10 [Mus musculus]
           >gi|127560|sp|P23249|MV10_MOUSE PROTEIN MOV-10
           >gi|110821|pir||A39611 probable GTP-binding protein -
           mouse >gi|53169|emb|CAA36803.1| (X52574) GTP binding
           protein [Mus musculus]
           Length = 1004
           
 Score = 91.7 bits (224), Expect = 2e-17
 Identities = 103/358 (28%), Positives = 163/358 (44%), Gaps = 73/358 (20%)

Query: 351 ARDIIREADVVLTTNSSAALEV-----VDYDTYDVAIIDEATQSTIPSILIPL------- 398
           A+  +++  V++TT  +A+  V     +D+ T+    IDEA     P  L+ +       
Sbjct: 610 AKKHLQQYRVLITTLITASRLVSAQFPIDHFTH--IFIDEAGHCMEPESLVAIAGLMDVK 667

Query: 399 ---NKVERFVLAGDHKQLPPTILSLEAQELSRTLFEGLIERY---------------PWK 440
              N   + VLAGD +QL P + S  A  L   L   L+ER                P  
Sbjct: 668 ETGNPGGQLVLAGDPRQLGPVLRSPLA--LKHGLGYSLLERLLAYNSLYKKGPNGYDPQF 725

Query: 441 SEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENV 500
              L+  YR +  I++ P++ +Y G++ A          D+V+ +     W  +      
Sbjct: 726 ITKLLRNYRSHPTILDIPNQLYYDGELQA--------CADVVDRER-FCRWEGLPQQGFP 776

Query: 501 IVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVK-------PEWIGVIT 553
           I+F        K ER+   S S  NP EA  V   + +LL+   K       P  +GVI+
Sbjct: 777 IIFHGVM---GKDEREGN-SPSFFNPEEAATVTSYLKQLLAPSSKKGKARLSPRNVGVIS 832

Query: 554 PYDDQ------------RDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNKLG---- 597
           PY  Q            R+L  +   +D++V +V+ +QG+E+ VI++S VRS++      
Sbjct: 833 PYRKQVEKIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLD 892

Query: 598 ---EIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGCFIEFPF 652
               +GFLK+ +R NV++TRAK  LIVVG+   L     +K  +EF KE G +   PF
Sbjct: 893 LDFNLGFLKNPKRFNVAVTRAKALLIVVGNPLLLGHDPDWKTFLEFCKENGGYTGCPF 950


>dbj|BAB13457.1| (AB046851) KIAA1631 protein [Homo sapiens]
           Length = 1032
           
 Score = 90.5 bits (221), Expect = 5e-17
 Identities = 106/366 (28%), Positives = 169/366 (45%), Gaps = 70/366 (19%)

Query: 342 DARKLEERI-ARDIIREADVVLTTNSSAALEV-----VDYDTYDVAIIDEATQSTIPSIL 395
           DA+K E    A+  ++E  V++TT  +A   V     +D+ T+    IDEA     P  L
Sbjct: 628 DAKKGEYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTH--IFIDEAGHCMEPESL 685

Query: 396 IPLNKVE----------RFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLI--------- 434
           + +  +           + VLAGD +QL P + S   Q+  L  +L E L+         
Sbjct: 686 VAIAGLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKG 745

Query: 435 -ERY-PWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWG 492
            + Y P     L+  YR +  I++ P++ +Y G++ A          D+V+ +     W 
Sbjct: 746 PDGYDPQFITKLLRNYRSHPTILDIPNQLYYEGELQA--------CADVVDRER-FCRWA 796

Query: 493 KILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVK------- 545
            +      I+F        K ER+   S S  NP EA  V   +  LL+   K       
Sbjct: 797 GLPRQGFPIIFHGVM---GKDEREGN-SPSFFNPEEAATVTSYLKLLLAPSSKKGKARLS 852

Query: 546 PEWIGVITPYDDQ------------RDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRS 593
           P  +GVI+PY  Q            R+L  +   +D++V +V+ +QG+E+ VI++S VRS
Sbjct: 853 PRSVGVISPYRKQVEKIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRS 912

Query: 594 NKLG-------EIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGC 646
           ++          +GFLK+ +R NV++TRAK  LI+VG+   L     +K  +EF KE G 
Sbjct: 913 SQSFVQLDLDFNLGFLKNPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCKENGG 972

Query: 647 FIEFPF 652
           +   PF
Sbjct: 973 YTGCPF 978


>emb|CAB63041.1| (AL022328) dJ402G11.8 (novel protein similar to mouse MOV10 (GB110)
           and yeast and plant predicted proteins) [Homo sapiens]
           Length = 417
           
 Score = 90.1 bits (220), Expect = 7e-17
 Identities = 105/362 (29%), Positives = 162/362 (44%), Gaps = 73/362 (20%)

Query: 335 QVQKAFDDARKLEERIARDIIREADVV-LTTNSSAALE---VVDYDTYDVAIIDEATQST 390
           QV  A  D+R L   +       AD+V L  + S  L+   +V    +    +DEA Q++
Sbjct: 42  QVHFALPDSRIL---VCAPSNSAADLVCLRLHESKVLQPATMVRVGHFTHVFVDEAGQAS 98

Query: 391 IPSILIPLNKVE----RFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSE-- 442
            P  LIPL  +     + VLAGD  QL P I S  A    L+ +  E L+ R  ++ +  
Sbjct: 99  EPECLIPLGLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDEN 158

Query: 443 --------------MLVVQYRMNERIMEFPSKEFYGGK--IIADESVRGITLRDLVEYQS 486
                          LV  YR +E ++  PS+ FY  +  + AD +V    L        
Sbjct: 159 AFGACGAHNPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLL-------- 210

Query: 487 PNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRE-------NPLEAEIVAK---IV 536
               W K+      ++F              RGSE+RE       NP EA  V +   ++
Sbjct: 211 ---GWEKLPKKGFPLIFHGV-----------RGSEAREGKSPSWFNPAEAVQVLRYCCLL 256

Query: 537 DKLLSIGVKPEWIGVITPYDDQRDLISMKVPE----DVEVKTVDGYQGREKEVIILSLVR 592
              +S  V    IGVITPY  Q + I + +      D++V +V+ +QG+E  VII+S VR
Sbjct: 257 AHSISSQVSASDIGVITPYRKQVEKIRILLRNVDLMDIKVGSVEEFQGQEYLVIIISTVR 316

Query: 593 SNK------LGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGC 646
           SN+         +GFL + +R NV++TR K  LIV+G+   L     +  ++E+    G 
Sbjct: 317 SNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRDPCFGALLEYSITNGV 376

Query: 647 FI 648
           ++
Sbjct: 377 YM 378


>dbj|BAA90895.1| (AK000033) unnamed protein product [Homo sapiens]
           Length = 338
           
 Score = 87.8 bits (214), Expect = 3e-16
 Identities = 91/310 (29%), Positives = 141/310 (45%), Gaps = 66/310 (21%)

Query: 383 IDEATQSTIPSILIPLNKVE----RFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIER 436
           +DEA Q++ P  LIPL  +     + VLAGD  QL P I S  A    L+ +  E L+ R
Sbjct: 12  VDEAGQASEPECLIPLGLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSR 71

Query: 437 YPWKSE----------------MLVVQYRMNERIMEFPSKEFYGGK--IIADESVRGITL 478
             ++ +                 LV  YR +E ++  PS+ FY  +  + AD +V    L
Sbjct: 72  PAYQRDENAFGACGAHNPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLL 131

Query: 479 RDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRE-------NPLEAEI 531
                       W K+      ++F              RGSE+RE       NP EA  
Sbjct: 132 -----------GWEKLPKKGFPLIFHGV-----------RGSEAREGKSPSWFNPAEAVQ 169

Query: 532 VAK---IVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE----DVEVKTVDGYQGREKE 584
           V +   ++   +S  V    +GVITPY  Q + I + +      D++V +V+  QG+E  
Sbjct: 170 VLRYCCLLAHSISSQVSASDVGVITPYRKQVEKIRILLRNVDLMDIKVGSVEELQGQEYL 229

Query: 585 VIILSLVRSNK------LGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMI 638
           VII+S VRSN+         +GFL + +R NV++TR K  LIV+G+   L     +  ++
Sbjct: 230 VIIISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRDPCFGALL 289

Query: 639 EFFKEKGCFI 648
           E+    G ++
Sbjct: 290 EYSITNGVYM 299


>emb|CAC15527.1| (AL121829) dJ697K14.7 (putative novel protein) [Homo sapiens]
           Length = 451
           
 Score = 85.0 bits (207), Expect = 2e-15
 Identities = 95/341 (27%), Positives = 150/341 (43%), Gaps = 78/341 (22%)

Query: 337 QKAFDDARKLEERIARDIIREADVVLTTNS---SAALEVVDYDTYDVAIIDEATQSTIPS 393
           +K   +ARK E       +   +V+L T S   SA+L+++D       ++DEA  +T P 
Sbjct: 84  KKVLWEARKFE-------LDRHEVILCTCSCAASASLKILDVRQI---LVDEAGMATEPE 133

Query: 394 ILIPL---NKVERFVLAGDHKQLPPTILSLEAQELSRTLFEGLIERYPWKSEMLVVQYRM 450
            LIPL    + E+ VL GDHKQL P + +   Q L   L   L ERY   + ML  QYRM
Sbjct: 134 TLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNLG--LDRSLFERYHEDAHMLDTQYRM 191

Query: 451 NERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDS----WGKILNPENVIVFIDT 506
           +E I  FPS  FY  K+   ++ +G+     V   +  +S    +G +   E  ++    
Sbjct: 192 HEGICAFPSVAFYKSKL---KTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTD 248

Query: 507 SKAENKWERQRRGSESRENPLEAEIVAKIVDKL-LSIGVKPEWIGVITPYDDQRDLISMK 565
              EN          S+ N  E   V +I  +L L   V+P+ I V+TPY+ Q   IS  
Sbjct: 249 EGNEN----------SKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKA 298

Query: 566 VPED----VEVKTVDGYQGR-------------------------EKEVIILSLVRSNKL 596
           +  +    V V ++   QG                          E   +++S VR+   
Sbjct: 299 LRREGIAGVAVSSITKSQGEAGGSWVGPGGWAQRQQGLTSHPAGSEWRYVLVSTVRTCAK 358

Query: 597 GE-------------IGFLKDLRRLNVSLTRAKRKLIVVGD 624
            +             +GF+ D  ++NV++TRA+  L ++G+
Sbjct: 359 SDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGE 399


>pir||G64575 conserved hypothetical protein HP0447 - Helicobacter pylori
           (strain 26695) >gi|2313555|gb|AAD07514.1| (AE000560)
           conserved hypothetical protein [Helicobacter pylori
           26695]
           Length = 360
           
 Score = 84.3 bits (205), Expect = 4e-15
 Identities = 91/310 (29%), Positives = 149/310 (47%), Gaps = 44/310 (14%)

Query: 363 TTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKV-ERFVLAGDHKQLPPTI---- 417
           T   + ALE  +   +D  I+DEA ++    +L+ +    ER +L GD +QLP  +    
Sbjct: 53  TGQHNQALERKETPYFDSVIVDEAAKANPLELLMVMALAKERIILVGDDRQLPHYLDDEI 112

Query: 418 ---LSLEAQE--------LSRTLFEGLIERYPWKSEM--------LVVQYRMNERIMEFP 458
              L  E+Q+        L  ++F+ L ER     E+        L +QY M+  + E  
Sbjct: 113 GKKLEDESQDAQDEIEKALKDSMFKKLKERAQKLKELDGKECFITLNMQYGMHPLLGELV 172

Query: 459 SKEFYGGKIIADES-VRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQR 517
           S  FY     + ES ++G  L +      P     ++L+    + +ID    E+K +R  
Sbjct: 173 SDVFYKPHNESFESPLKGKHLEE-----KPFKHNLRVLD-NKPLAWIDVK--ESKEKRNA 224

Query: 518 RGSESRENPLEAEIVAKIVDKLLSIGVKPE---WIGVITPYDDQRDLI--SMKVPEDVEV 572
            GS  RE+ + A      + + L + +K E     GVIT + +Q+ L+  ++K   ++E+
Sbjct: 225 DGSYYRESEITA------IKECLDLFMKDEPDFTFGVITFFSEQKRLLEQALKGYANLEI 278

Query: 573 KTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHE 632
            TVD +QG+E +V+ LS VR+      GFLK    L V+L+R KR LIV GD     + E
Sbjct: 279 GTVDSFQGKEFDVVFLSSVRTRHTEGFGFLKISSCLCVALSRQKRALIVAGDREKFDTPE 338

Query: 633 TYKKMIEFFK 642
           +  K+   F+
Sbjct: 339 SKDKVSGLFE 348


>pir||B75198 DNA helicase related protein PAB0067 - Pyrococcus abyssi  (strain
            Orsay) >gi|5457542|emb|CAB49033.1| (AJ248283) DNA
            HELICASE RELATED PROTEIN [Pyrococcus abyssi]
            Length = 1308
            
 Score = 83.1 bits (202), Expect = 9e-15
 Identities = 129/517 (24%), Positives = 208/517 (39%), Gaps = 145/517 (28%)

Query: 171  LNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNL 230
            LN  QRK +           + GP GTGKT   +            VLA A S +     
Sbjct: 839  LNEDQRKFVLDI--DHRIVTLQGPPGTGKTSGAI---------APAVLARAYSTI----- 882

Query: 231  VERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYT 290
              +  +S + IV        +   H      LI  + L  EL+ ++ +            
Sbjct: 883  --KQGKSALFIV--------TALSHRAVNEALIRTYRLKEELKNIKEL------------ 920

Query: 291  KPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERI 350
                +  RG+S EE I+  +R+ G               IK++ + +  F  +       
Sbjct: 921  -KNVELIRGVSGEEAIEPMKRELGG--------------IKVDIRARFTFSKST------ 959

Query: 351  ARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVE-RFVLAGD 409
               +     ++  T  +    V +Y+  D+ +IDEA+   +P  L+     + + +L GD
Sbjct: 960  ---LFPTVKILFATPQTVFKLVKNYEA-DLVVIDEASMMDLPMFLLATKNAKGQVLLVGD 1015

Query: 410  HKQLPPTIL-----------------------------SLEAQELSRTLFEGLIERYP-- 438
            H+Q+ P  +                              LE +EL R  F+ ++ R P  
Sbjct: 1016 HRQMQPIQVHEWELEDRKTIEEHLPFLSALNFIRFLRGELEERELKR--FKRILGRNPPK 1073

Query: 439  WKSEM--------LVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSP--- 487
            WK +         L   +R+ + + E  S+ FY        S  GI LR   E       
Sbjct: 1074 WKVDKEDVLPMHRLRETFRLPQALAELHSELFY--------SFDGIKLRSRKEPSEEIAR 1125

Query: 488  -------NDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLL 540
                   N+    IL+P+  +V I              GS S+ N LEA IV +IV+ L 
Sbjct: 1126 ALRNAGKNEFLRFILDPDYPVVLI---------VHDENGS-SKVNELEAGIVKEIVEALN 1175

Query: 541  SIGVKPEWIGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNK---LG 597
             + V     GV+ PY  Q+ LI   V  +V+V TV+ +QG E+++II+S+  S+    L 
Sbjct: 1176 GVDV-----GVVVPYRAQKRLIRSLV--NVQVDTVERFQGGERDIIIVSMTSSDPSYLLK 1228

Query: 598  EIGFLKDLRRLNVSLTRAKRKLIVVGDSS--TLSSHE 632
             + FL D  RLNV+ +RA+ KLI++   +  TLS+ +
Sbjct: 1229 VMDFLYDPNRLNVAGSRAREKLILIASRNLFTLSARD 1265


>emb|CAB60444.1| (AL132853) cDNA EST yk10h1.5 comes from this gene~cDNA EST yk27d4.5
           comes from this gene~cDNA EST yk42b2.5 comes from this
           gene~cDNA EST yk49b5.5 comes from this gene~cDNA EST
           yk147h7.5 comes from this gene~cDNA EST yk192e10.5 comes
           from this gene~cDNA>
           Length = 1212
           
 Score = 82.7 bits (201), Expect = 1e-14
 Identities = 87/299 (29%), Positives = 139/299 (46%), Gaps = 46/299 (15%)

Query: 354 IIREADVVLTTNSSAAL---EVVDYD-TYDVAIIDEATQSTIPSILIPL---------NK 400
           +++EA ++  T + AAL   E+V     YD  +++EA Q       IPL         N+
Sbjct: 710 LVKEAKIIAMTCTHAALRRNELVKLGFRYDNIVMEEAAQILEVETFIPLLLQNPQDGHNR 769

Query: 401 VERFVLAGDHKQLPPTILSLEAQELS---RTLFEGLIERYPWKSEMLVVQYRMNERIMEF 457
           ++R+++ GDH QLPP + +   Q+ S   ++LF  L+ R    +  L  Q R   +I E 
Sbjct: 770 LKRWIMIGDHHQLPPVVQNQAFQKYSNMEQSLFARLV-RLSVPNVQLDRQGRARAQIAEL 828

Query: 458 PSKEFYG-GKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQ 516
               + G G +     V G     L ++Q+ N  +           FID        E Q
Sbjct: 829 YQWRYNGLGNL---PHVDG-----LPQFQNANAGFAFPFQ------FIDIPDFNGHGETQ 874

Query: 517 RRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLI----------SMKV 566
                  +N  EAE    +   +  +G   E I ++T Y+ Q  LI          +  +
Sbjct: 875 P-SPHFYQNLGEAEYACALYTYMRILGYPAEKISILTTYNGQAQLIRDVFQRRCDTNPLI 933

Query: 567 PEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDS 625
               +V TVD YQG++ + IILSLV++  +G I   +D+RRL V+L+RA+  L V+G S
Sbjct: 934 GMPAKVSTVDKYQGQQNDFIILSLVKTRNIGHI---RDVRRLVVALSRARLGLYVLGRS 989


>pir||T46441 hypothetical protein DKFZp434C0927.1 - human
           >gi|6808062|emb|CAB70881.1| (AL137700) hypothetical
           protein [Homo sapiens]
           Length = 239
           
 Score = 82.7 bits (201), Expect = 1e-14
 Identities = 65/209 (31%), Positives = 100/209 (47%), Gaps = 32/209 (15%)

Query: 440 KSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPEN 499
           K  +L  QYR +  I    +  FY G ++      G+T  +    +SP   W   L   N
Sbjct: 4   KPILLRTQYRCHPAISAIANDLFYKGALM-----NGVTEIE----RSPLLEWLPTLCFYN 54

Query: 500 VIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQR 559
           V           K   Q     S  N  EA    K++  L++ G+    IGVIT Y  Q 
Sbjct: 55  V-----------KGLEQIERDNSFHNVAEATFTLKLIQSLIASGIAGSMIGVITLYKSQM 103

Query: 560 -------DLISMKVPE--DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNV 610
                    +    P+   V+V TVD +QG EKE+IILS VR+    ++GF+   +R+NV
Sbjct: 104 YKLCHLLSAVDFHHPDIKTVQVSTVDAFQGAEKEIIILSCVRTR---QVGFIDSEKRMNV 160

Query: 611 SLTRAKRKLIVVGDSSTLSSHETYKKMIE 639
           +LTR KR L++VG+ + L  ++ + ++I+
Sbjct: 161 ALTRGKRHLLIVGNLACLRKNQLWGRVIQ 189


>pir||T27684 hypothetical protein ZK1067.2 - Caenorhabditis elegans
            >gi|3881525|emb|CAA93884.1| (Z70038) cDNA EST yk19a4.3
            comes from this gene~cDNA EST yk19a4.5 comes from this
            gene~cDNA EST yk224b3.5 comes from this gene~cDNA EST
            yk357f10.5 comes from this gene~cDNA EST yk518c10.5 comes
            from this gene [Caenorhabditis elegans]
            Length = 2219
            
 Score = 81.5 bits (198), Expect = 3e-14
 Identities = 101/392 (25%), Positives = 181/392 (45%), Gaps = 59/392 (15%)

Query: 278  IGQSLAEKRDTYTKPTPKFRRGLSD-EEIIKLAERKRGARGLSARLIMEMAEWIKLNRQV 336
            I   ++E +D      P  ++ L+D + I  LA  KR +  ++    +       L RQ+
Sbjct: 1124 INNLVSEIKDMILSSQPVPKKDLNDIKYIFSLARLKRWSLYITWCDALRSIVTENLPRQI 1183

Query: 337  QK---AFDDARKLEERIARDIIREADVV--LTTNSSAALEVVDYDTYDVAIIDEATQSTI 391
            ++   A ++ +  + R+  +I+R   ++   TT  S     ++     + I++EA +   
Sbjct: 1184 REYREACENFKNAQNRVDAEIMRMTMIIGATTTGCSRLRPTLEKVGPRILIVEEAAEVLE 1243

Query: 392  PSILIPL-NKVERFVLAGDHKQLPPTILSLE---AQELSRTLFEGLIER-YPWKSEMLVV 446
              I+  + + VE  V+ GDHKQL P     E   A  L  ++FE L+ER  P+    L  
Sbjct: 1244 AHIISAMISTVEHVVMIGDHKQLRPNPAVHELGVAYGLRISMFERLVERGLPFSQ--LRQ 1301

Query: 447  QYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPE------NV 500
            Q+RMN                I+D+ V+      L  Y +  D+    L P+      N+
Sbjct: 1302 QHRMN--------------LTISDKIVK------LSFYDNVTDAENVGLYPDVQGMATNL 1341

Query: 501  IVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRD 560
              +  TS  E+  E       S  N  E  +   +V  LL        I V+  Y  Q++
Sbjct: 1342 FFWSHTSMEESPDE------VSWLNKHEISMTVALVKHLLKQNYTTNDIVVLATYSAQKN 1395

Query: 561  LISMK-------VPED--VEVKTVDGYQGREKEVIILSLVRSNKLGE----IGFLKDLRR 607
            L+  +        P+   + V+TVD +QG+E++++I+SLVRS++ G     IGFL    R
Sbjct: 1396 LMYREYANVFGSTPDSNVIPVETVDSFQGKERKIVIVSLVRSHRGGRENTGIGFLAVANR 1455

Query: 608  LNVSLTRAKRKLIVVGDSS-TLSSHETYKKMI 638
            + V+LTRA+  + ++G+ +  +++ E + K++
Sbjct: 1456 ICVALTRAQHGMYIIGNGAYIMNNSELWNKIV 1487


>pir||T23039 hypothetical protein H03G16.3 - Caenorhabditis elegans
           >gi|3877990|emb|CAB07226.1| (Z92790) H03G16.3
           [Caenorhabditis elegans]
           Length = 646
           
 Score = 81.1 bits (197), Expect = 3e-14
 Identities = 89/323 (27%), Positives = 141/323 (43%), Gaps = 55/323 (17%)

Query: 353 DIIREADVVLTTNSSAALE-VVDYDTYDVA--IIDEATQSTIPSILIPLNKVERFVLAGD 409
           D+I    VVL T  +  L  V   +  D +  IIDEA           + K + FV+AGD
Sbjct: 196 DMIGNVLVVLATIGADFLNFVAKQEALDPSFCIIDEAGLVMASETWPDVYKSKGFVIAGD 255

Query: 410 HKQLPPTILS-------------LEAQELSRTLFEGLIERYPWKSE-----MLVVQYRMN 451
             +L P I +             LE + L   +   +++    K+E     +L  QYR N
Sbjct: 256 PNELFPQIYNHDNGNGFFNQFCCLEQKRLETQV--SILDCINEKTENLSPIILDTQYRSN 313

Query: 452 ERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPE-NVIVFIDTSKAE 510
           E IM + +  FY  K+  D     +TLR   +        G   NP  +  V +DTS  E
Sbjct: 314 ETIMAWSNACFYNPKVKTDFKCGSLTLRSFFK--------GSKFNPLFHPFVIVDTS-CE 364

Query: 511 NKWERQRRG-----------SESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQR 559
            + E++              +E   N  EA+I      +LL + V+   I +ITPY  Q 
Sbjct: 365 KEMEKRNETFEYLVFNNNNENEGYANVAEAKIAMHHYKQLLKLKVQASDIAIITPYRGQS 424

Query: 560 DLISMKVPE-----------DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRL 608
            ++   + +           D  V  VD   G+E +V+I ++VRSN   ++G   D RRL
Sbjct: 425 HVVRQMMRKFANEESRSDCFDTHVGDVDKIVGKEFDVVIFTMVRSNPKLDMGKAGDPRRL 484

Query: 609 NVSLTRAKRKLIVVGDSSTLSSH 631
           +V +T+AK+  + +G+   L+ +
Sbjct: 485 HVIITKAKKHFMFIGNGFLLAEN 507


>gb|AAF54715.1| (AE003693) CG14730 gene product [Drosophila melanogaster]
            Length = 1170
            
 Score = 80.8 bits (196), Expect = 4e-14
 Identities = 92/333 (27%), Positives = 158/333 (46%), Gaps = 50/333 (15%)

Query: 338  KAFDDARKLEERIARDIIREADVVLTTNSSAAL---EVVDYD-TYDVAIIDEATQSTIPS 393
            +AF+  R   +R    +++EA ++  T + AAL   E+V+    YD  +++E+ Q     
Sbjct: 712  RAFELLRTGLDRSKYLLVKEAKIIAMTCTHAALKRKELVNLGFRYDNILMEESAQILEIE 771

Query: 394  ILIPL---------NKVERFVLAGDHKQLPPTILSLEAQELS---RTLFEGLIERYPWKS 441
              IPL         N+++R+++ GDH QLPP I ++  Q+ S   ++LF  L+ R    +
Sbjct: 772  TFIPLLLQNPLDGLNRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRLV-RLGVPT 830

Query: 442  EMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVI 501
              L  Q R    I        Y  +    E ++ I  RD  EY+  N  +       NV 
Sbjct: 831  VDLDGQGRARASIC-----SLYKWRYKKLEDLQHIFERD--EYKQANPGFVHDYQLINVE 883

Query: 502  VFIDTSKAE-NKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQ-- 558
             F    ++E N +  Q        N  EAE +  +   +  +G     I ++T Y+ Q  
Sbjct: 884  DFKGVGESEPNPYFYQ--------NLAEAEYIVAVYMYMRLLGYPAAKISILTTYNGQKH 935

Query: 559  --RDLISMKVPEDV------EVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNV 610
              RD+I+ +   +       ++ TVD YQG++ + I++SLVR+     +G L+D+RRL V
Sbjct: 936  LIRDVINARCGNNPLIGWPHKITTVDKYQGQQNDYILISLVRTK---AVGHLRDVRRLVV 992

Query: 611  SLTRAKRKLIVVGDSS----TLSSHETYKKMIE 639
            +++RA+  L V G  S     L   +T+K + +
Sbjct: 993  AMSRARLGLYVFGRVSLFKNCLELQQTFKLLTQ 1025


>emb|CAB65628.1| (AL049766) dJ686N3.2 (novel protein similar to plant, yeast, worm,
            bacterial and human (predicted) proteins) [Homo sapiens]
            Length = 1814
            
 Score = 78.4 bits (190), Expect = 2e-13
 Identities = 46/134 (34%), Positives = 74/134 (54%), Gaps = 4/134 (2%)

Query: 514  ERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQ----RDLISMKVPED 569
            E++ +  +S +N  EA  V ++    L     P  I ++T Y  Q    R L+  K    
Sbjct: 1015 EQEIQEGKSHQNQHEAHFVVELCKYFLCQEYLPSQITILTTYTGQLFCLRKLMPAKTFAG 1074

Query: 570  VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLS 629
            V V  VD YQG E ++I+LSLVRSN+ G++GFL+   R+ V+L+RAK+ +  +G+   L+
Sbjct: 1075 VRVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQISNRICVALSRAKKGMYCIGNMQMLA 1134

Query: 630  SHETYKKMIEFFKE 643
                + K+I   +E
Sbjct: 1135 KVPLWSKIIHTLRE 1148


>pir||T29386 hypothetical protein K08D10.5 - Caenorhabditis elegans
           >gi|1280167|gb|AAA98031.1| (U55857) K08D10.5 gene
           product [Caenorhabditis elegans]
           Length = 602
           
 Score = 76.9 bits (186), Expect = 7e-13
 Identities = 86/345 (24%), Positives = 147/345 (41%), Gaps = 41/345 (11%)

Query: 325 EMAEWIKLNRQVQKA-----FDDARKLEERIARDIIREADVVLTTNSSAALEVVDY---- 375
           E  EWI +  ++ KA     F+   K E  I R  ++  D  L   ++AA+++       
Sbjct: 250 EPNEWIVMAARLLKAAVKLPFNTIPK-EINIFRVFMKLYDPQLIIGTAAAIQLAFNQPDL 308

Query: 376 ----DTYDVAIIDEATQSTIPSI--LIPLNKVERFVLAGDHKQLPPTILSLEAQELSRTL 429
               D +D+  IDEA+Q  +  +  L  L    R +L GD  QLPP        EL R  
Sbjct: 309 AEIKDLFDITFIDEASQLALYVLGSLATLLPKTRIILVGDMHQLPPYTEDALPAELKRAA 368

Query: 430 F-EGL---IERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIAD-ESVRGITLRDLVEY 484
             E L   ++   W S  L   +R  + I +     FYG  + +  ++V  + + + +E 
Sbjct: 369 VGEPLTLAVKGRRWSSMHLTRVHRCPKMITDLLGAVFYGNTLTSTRKAVNRVPILEAMEL 428

Query: 485 QSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGV 544
            S            +  VF+      N   +Q +  +S  N  EA    ++V  L     
Sbjct: 429 PS-----------HHPFVFV------NYISQQTQVGKSFSNENEARYALQLVTALKRHAR 471

Query: 545 KPEW---IGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIGF 601
           +      + V+  Y  Q   +     + V V T+DG QG+E +V I+ L RS+   +  F
Sbjct: 472 EQNTTVSVAVLNFYGAQYSYVYSIAEDGVRVNTIDGCQGQEYDVSIVLLTRSDPYEKSKF 531

Query: 602 LKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGC 646
           L +  R+NV+L+R+K   +V+G    + +H   ++      ++ C
Sbjct: 532 LVNPNRINVALSRSKMATVVIGQRHLIGNHPNVQQAKRGRYQRSC 576


>sp|Q09449|YQ12_CAEEL HYPOTHETICAL 175.7 KD PROTEIN C05C10.2 IN CHROMOSOME II
            >gi|7495408|pir||T18941 hypothetical protein C05C10.2 -
            Caenorhabditis elegans >gi|3874068|emb|CAA88201.1|
            (Z48178) similarity with yeast NAM7 protein (Swiss Prot
            accession number P30771) and may possibly interact with
            DNA or RNA~cDNA EST yk43d4.3 comes from this gene~cDNA
            EST yk7f5.5 comes from this gene~cDNA EST yk68h2.5 comes
            from this gene~cDNA EST yk13>
            Length = 1551
            
 Score = 72.6 bits (175), Expect = 1e-11
 Identities = 81/298 (27%), Positives = 139/298 (46%), Gaps = 31/298 (10%)

Query: 360  VVLTTNSSAALEVVDYDTYDVAIIDEATQ---STIPSILIPLNKVERFVLAGDHKQLPPT 416
            V++T +S+  L  +  D   V I DEA+Q    T+  +L   N    F L GD  QLPP 
Sbjct: 1186 VMVTADSAKGLLNILRDVCAVQI-DEASQLAECTLLGLLKSFNNAS-FGLIGDIHQLPPY 1243

Query: 417  ILSLEAQELSRTLFEGLIERYPWKSEMLVV-----QYRMNERIMEFPSKEFYGGKIIADE 471
                   +L        +ER   K +M  V      YR + +  E  S+ FY G +++  
Sbjct: 1244 CEEGLEGKLKDFGIGNTMER-AIKEKMFPVCTLRNVYRCHPKTTELLSELFYDGALVS-- 1300

Query: 472  SVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEI 531
               G++     ++ +  D +    NP+  ++F++ + A  K         S  N  E  I
Sbjct: 1301 ---GVSELARSDFMTKRDDFWP--NPKFPMMFVNNTGASTKM------GTSTSNSSEKSI 1349

Query: 532  VAKIVDKLLSIG---VKPEWIGVITPYDDQRDLISMKVP-EDVEVKTVDGYQGREKEVII 587
            V +IV  L++     V P  IGVI+ Y  Q  +++  +    V+  TVD +QG EKE+II
Sbjct: 1350 VGEIVQNLINDPRNPVNPSDIGVISFYSAQTSILTEHLRGSGVKCGTVDAFQGSEKEIII 1409

Query: 588  LSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKG 645
            +    + ++ +  F++   RLNV+++RAK+  I++G    L     +  ++   ++ G
Sbjct: 1410 MCST-NERISD--FMQLSNRLNVAMSRAKQVTIIIGHLDGLRRANYWSTIVNKIEQNG 1464


>pir||T23869 hypothetical protein R03D7.2 - Caenorhabditis elegans
           >gi|3878792|emb|CAA86856.1| (Z46828) similar to helicase
           domain~cDNA EST yk138d12.5 comes from this gene~cDNA EST
           yk138d12.3 comes from this gene [Caenorhabditis elegans]
           Length = 542
           
 Score = 72.2 bits (174), Expect = 2e-11
 Identities = 73/275 (26%), Positives = 120/275 (43%), Gaps = 27/275 (9%)

Query: 358 ADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSI--LIPLNKVERFVLAGDHKQLPP 415
           A + L  + +  LE+ D   +D+  IDEA+Q  +  +  L  +    R +L GD  QLPP
Sbjct: 198 AAIKLAFSQAPFLEIKD--RFDITFIDEASQLALYVLGSLATMLPKSRMILVGDMHQLPP 255

Query: 416 TILSLEAQELSRTLF-EGL---IERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADE 471
            +      EL R    E L   ++   W S  L   +R  + I E     FYG  + + +
Sbjct: 256 YMEEALPAELKRAAIGEPLTLAVKGRRWPSMHLTRVHRCPKMITEVLGDLFYGNTLTSSK 315

Query: 472 SVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEI 531
              G+T   +++           L   + +VF+      N    Q    +S  N  EA  
Sbjct: 316 P--GVTDIPVLKAMG--------LPSRHPMVFV------NYTSPQTAVGKSFSNEGEARY 359

Query: 532 VAKIVDKLL---SIGVKPEWIGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIIL 588
             ++V+ L    S   K     ++  Y  Q   +     ++V V T+DG QG+E +V I+
Sbjct: 360 ALQLVEALTRYASTANKKITAAILNFYGAQYSYVYSMAEDEVTVNTIDGCQGQEYDVTIV 419

Query: 589 SLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVG 623
            L RS+      FL +  R+NV+L+R K   +++G
Sbjct: 420 LLTRSDPYERSKFLVNANRINVALSRPKIATVIIG 454


>pir||S75309 hypothetical protein sll1582 - Synechocystis sp. (strain PCC 6803)
            >gi|1652300|dbj|BAA17223.1| (D90904) hypothetical protein
            [Synechocystis sp.]
            Length = 1118
            
 Score = 71.8 bits (173), Expect = 2e-11
 Identities = 87/319 (27%), Positives = 137/319 (42%), Gaps = 68/319 (21%)

Query: 378  YDVAIIDEATQST---IPSILIPLNKVERFVLAGDHKQLPPTILSLEAQ----------- 423
            +D  IIDEA+Q T   +  I++  NK   FVL GD KQLP  I   E +           
Sbjct: 806  FDQLIIDEASQLTEADLAGIVVLFNK---FVLIGDQKQLPAVITQNEEECRVEVEPFRRY 862

Query: 424  -----ELSRTLFEGLIERYPWKS-----EMLVVQYRMNERIMEFPSKEFYGGKIIADESV 473
                 +L  +LFE LI     K        L   YRM+  I    +  +    +   +  
Sbjct: 863  AINISDLRISLFERLINNAKNKGWNHCYGQLTEHYRMHRDIASLIAHHYDRPLVEQTQEQ 922

Query: 474  RGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVA 533
            R I   +     + ND   K+     + +           E     S  R+N  EA I A
Sbjct: 923  RKI---ESSYENNDNDLLSKLSKSRTIFI-----------ETPSETSIQRKNTNEAIIAA 968

Query: 534  KIV-----DKLLSIGVKPEWIGVITPYDDQRDLISMKVP----------EDVEVKTVDGY 578
             IV     +KLL +      IG+I P+  Q   I+ ++           + + V TV+ +
Sbjct: 969  TIVKTYWENKLLPMAE----IGIIAPFRAQVAEINQQLEKIFAGADFSRDSIVVDTVERF 1024

Query: 579  QGREKEVIILS--LVRSNKLGEIGFLKDL------RRLNVSLTRAKRKLIVVGDSSTLSS 630
            QG E+E+II S  +  S ++  I  + D       R+L VS++RAK KL+++G+SS L  
Sbjct: 1025 QGDERELIIFSTTISWSKQVKNIQSIADGDRQGTDRKLLVSISRAKSKLVILGNSSQLQF 1084

Query: 631  HETYKKMIEFFKEKGCFIE 649
               Y+++I+  ++    I+
Sbjct: 1085 APAYRELIKHIEQSNGLID 1103


>dbj|BAB14299.1| (AK022902) unnamed protein product [Homo sapiens]
           Length = 324
           
 Score = 71.8 bits (173), Expect = 2e-11
 Identities = 34/80 (42%), Positives = 57/80 (70%), Gaps = 1/80 (1%)

Query: 571 EVKTVDGYQGREKEVIILSLVRSNKL-GEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLS 629
           EV TVD +QGR+K+ +I++ VR+N + G IGFL  L+RLNV++TRAK  L ++G   TL 
Sbjct: 17  EVDTVDAFQGRQKDCVIVTCVRANSIQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLM 76

Query: 630 SHETYKKMIEFFKEKGCFIE 649
            ++ + ++I+  +++G  I+
Sbjct: 77  ENQHWNQLIQDAQKRGAIIK 96


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.318    0.137    0.381 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 223438808
Number of Sequences: 2977
Number of extensions: 9185145
Number of successful extensions: 30231
Number of sequences better than 1.0e-10: 98
Number of HSP's better than  0.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 60
Number of HSP's that attempted gapping in prelim test: 29766
Number of HSP's gapped (non-prelim): 166
length of query: 653
length of database: 189,106,746
effective HSP length: 61
effective length of query: 592
effective length of database: 152,599,039
effective search space: 90338631088
effective search space used: 90338631088
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 168 (69.9 bits)