BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1561 (PAB1561) DE:DNA helicase, putative (653 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||B75105 probable DNA helicas PAB1561 - Pyrococcus abyssi (st... 1279 0.0 pir||E71080 probable DNA-binding protein - Pyrococcus horikoshii... 1116 0.0 pir||G72429 hypothetical protein TM0005 - Thermotoga maritima (s... 792 0.0 gi|11498984 DNA helicase, putative [Archaeoglobus fulgidus] >gi|... 737 0.0 pir||D69085 transcription control factor enhancer-binding protei... 687 0.0 sp|Q57568|Y104_METJA HYPOTHETICAL ATP-BINDING PROTEIN MJ0104 >gi... 540 e-152 pir||D70476 DNA helicase - Aquifex aeolicus >gi|2984278|gb|AAC07... 461 e-129 pir||T02699 hypothetical protein T18E12.6 - Arabidopsis thaliana... 352 6e-96 emb|CAC16347.1| (AJ300306) putative helicase [Arabidopsis thaliana] 351 1e-95 gb|AAG28561.1|AF199411_1 (AF199411) antifreeze-enhancer binding ... 300 3e-80 gi|4504623 immunoglobulin mu binding protein 2 [Homo sapiens] >g... 299 7e-80 pir||A47500 Ig mu chain switch region binding protein 2 - human 299 7e-80 gi|11435569 immunoglobulin mu binding protein 2 [Homo sapiens] 298 2e-79 sp|Q60560|SMB2_MESAU DNA-BINDING PROTEIN SMUBP-2 (IMMUNOGLOBULIN... 296 5e-79 gb|AAA70430.1| (L24544) DNA helicase [Homo sapiens] 295 8e-79 gi|6678029 immunoglobulin S mu binding protein 2 [Mus musculus] ... 294 1e-78 pir||T41580 probable dna-binding protein - fission yeast (Schiz... 262 1e-68 gi|6322835 DNA helicase A; Hcs1p [Saccharomyces cerevisiae] >gi|... 230 3e-59 dbj|BAB09253.1| (AB026643) DNA helicase-like [Arabidopsis thaliana] 219 6e-56 pir||D72258 helicase-related protein - Thermotoga maritima (stra... 215 9e-55 emb|CAC18314.1| (AL451022) probable HUPF1 protein [Neurospora cr... 215 2e-54 pir||T43280 nonsense-mediated mRNA decay trans-acting factor - C... 206 6e-52 gi|6323726 putative helicase; Nam7p [Saccharomyces cerevisiae] >... 202 1e-50 dbj|BAB10240.1| (AB013394) prematurely terminated mRNA decay fac... 200 3e-50 pir||T40065 tRNA-splicing endonuclease positive effector - fissi... 197 3e-49 gb|AAB94785.1| (AC003972) pNORF1 [Homo sapiens] >gi|3328175|gb|A... 192 7e-48 gb|AAC51140.1| (U59323) type 1 RNA helicase pNORF1 [Homo sapiens] 192 7e-48 dbj|BAA19664.1| (D86988) KIAA0221 [Homo sapiens] 192 7e-48 sp|Q09820|YAC6_SCHPO HYPOTHETICAL 105.6 KD PROTEIN C16C9.06C IN ... 191 2e-47 pir||T37779 probable regulator of nonsense transcript stability ... 191 2e-47 gi|11426635 regulator of nonsense transcripts 1 [Homo sapiens] 190 4e-47 gi|4506479 regulator of nonsense transcripts 1 [Homo sapiens] >g... 190 5e-47 sp|Q92355|YDHA_SCHPO HYPOTHETICAL 192.5 KD PROTEIN C6G9.10C IN C... 184 3e-45 emb|CAC10094.1| (AL442164) related to SEN1 protein [Neurospora c... 174 2e-42 gb|AAB63976.1| (M74589) SEN1 [Saccharomyces cerevisiae] 167 3e-40 gi|6323462 component of a nuclear-localized tRNA splicing comple... 167 3e-40 gb|AAG19799.1| (AE005064) DNA helicase; Hel [Halobacterium sp. N... 167 4e-40 gi|6321024 DNA Helicase I; Ecm32p [Saccharomyces cerevisiae] >gi... 161 3e-38 pir||T39568 hypothetical helicase - fission yeast (Schizosacchar... 159 1e-37 pir||T51292 Dna2p - fission yeast (Schizosaccharomyces pombe) >g... 159 1e-37 gb|AAF99770.1|AC003981_20 (AC003981) F22O13.33 [Arabidopsis thal... 158 2e-37 sp|P51530|Y083_HUMAN HYPOTHETICAL PROTEIN KIAA0083 >gi|11360302|... 158 2e-37 pir||T08986 hypothetical protein F6G3.130 - Arabidopsis thaliana... 157 5e-37 pir||T26415 hypothetical protein Y106G6D.5 - Caenorhabditis eleg... 153 5e-36 pir||T00533 SEN1 protein homolog T20K24.14 - Arabidopsis thalian... 152 2e-35 dbj|BAA31600.1| (AB014525) KIAA0625 protein [Homo sapiens] 148 2e-34 gi|7662212 KIAA0625 protein [Homo sapiens] >gi|7022724|dbj|BAA91... 148 2e-34 gi|11429653 KIAA0625 protein [Homo sapiens] 148 2e-34 gb|AAG20303.1| (AE005104) DNA binding protein eukaryotic-like; D... 147 4e-34 gb|AAF23837.1|AC007234_9 (AC007234) F1E22.14 [Arabidopsis thaliana] 142 1e-32 gb|AAG09081.1|AC026237_2 (AC026237) Similar to tRNA-splicing end... 138 1e-31 gb|AAF50482.1| (AE003556) CG7504 gene product [Drosophila melano... 137 3e-31 pir||T28788 hypothetical protein C41D11.7 - Caenorhabditis elega... 136 1e-30 dbj|BAB11057.1| (AB015478) contains similarity to nonsense-media... 135 1e-30 gb|AAF57908.1| (AE003804) CG6967 gene product [Drosophila melano... 134 2e-30 gi|6321958 DNA replication helicase; Dna2p [Saccharomyces cerevi... 134 3e-30 dbj|BAB11372.1| (AB017068) contains similarity to nonsense-media... 131 2e-29 gb|AAB67523.1| (U21094) Sen1p [Saccharomyces cerevisiae] 131 3e-29 pir||T22132 hypothetical protein F43G6.1a - Caenorhabditis elega... 131 3e-29 pir||T22138 hypothetical protein F43G6.1b - Caenorhabditis elega... 131 3e-29 gi|11499542 DNA helicase, putative [Archaeoglobus fulgidus] >gi|... 130 4e-29 dbj|BAB11370.1| (AB017068) contains similarity to nonsense-media... 127 4e-28 pir||T00740 hypothetical protein F22O13.35 - Arabidopsis thaliana 125 1e-27 dbj|BAB08973.1| (AB024026) gb|AAD48967.1~gene_id:K15O15.6~strong... 122 1e-26 dbj|BAB11373.1| (AB017068) contains similarity to DNA helicase~g... 122 1e-26 gb|AAD48967.1|AF147263_9 (AF147263) contains similarity to nonse... 122 2e-26 gb|AAF23836.1|AC007234_8 (AC007234) F1E22.16 [Arabidopsis thaliana] 122 2e-26 gb|AAF46543.1| (AE003449) CG2990 gene product [Drosophila melano... 120 4e-26 gb|AAF56255.1| (AE003746) CG6204 gene product [Drosophila melano... 115 2e-24 gb|AAA58611.1| (M64979) glial factor-1 [Homo sapiens] 115 2e-24 pir||A70369 hypothetical protein aq_791 - Aquifex aeolicus >gi|2... 112 1e-23 pir||D64588 probable DNA helicase - Helicobacter pylori (strain ... 109 9e-23 pir||T41111 hypothetical ATP binding protein - fission yeast (S... 101 2e-20 gb|AAF79736.1|AC005106_17 (AC005106) T25N20.11 [Arabidopsis thal... 99 1e-19 gb|AAF58307.1| (AE003816) CG6701 gene product [Drosophila melano... 96 9e-19 dbj|BAA92642.1| (AB037825) KIAA1404 protein [Homo sapiens] 95 2e-18 dbj|BAB14696.1| (AK023836) unnamed protein product [Homo sapiens] 95 2e-18 pir||T42668 hypothetical protein DKFZp434B0717.1 - human (fragme... 95 3e-18 pir||T47242 DNA helicase homolog - fission yeast (Schizosaccharo... 93 8e-18 gb|AAF47775.1| (AE003478) CG11513 gene product [Drosophila melan... 92 2e-17 gi|6678920 Moloney leukemia virus 10 [Mus musculus] >gi|127560|s... 92 2e-17 dbj|BAB13457.1| (AB046851) KIAA1631 protein [Homo sapiens] 90 5e-17 emb|CAB63041.1| (AL022328) dJ402G11.8 (novel protein similar to ... 90 7e-17 dbj|BAA90895.1| (AK000033) unnamed protein product [Homo sapiens] 88 3e-16 emb|CAC15527.1| (AL121829) dJ697K14.7 (putative novel protein) [... 85 2e-15 pir||G64575 conserved hypothetical protein HP0447 - Helicobacter... 84 4e-15 pir||B75198 DNA helicase related protein PAB0067 - Pyrococcus ab... 83 9e-15 emb|CAB60444.1| (AL132853) cDNA EST yk10h1.5 comes from this gen... 83 1e-14 pir||T46441 hypothetical protein DKFZp434C0927.1 - human >gi|680... 83 1e-14 pir||T27684 hypothetical protein ZK1067.2 - Caenorhabditis elega... 82 3e-14 pir||T23039 hypothetical protein H03G16.3 - Caenorhabditis elega... 81 3e-14 gb|AAF54715.1| (AE003693) CG14730 gene product [Drosophila melan... 81 4e-14 emb|CAB65628.1| (AL049766) dJ686N3.2 (novel protein similar to p... 78 2e-13 pir||T29386 hypothetical protein K08D10.5 - Caenorhabditis elega... 77 7e-13 sp|Q09449|YQ12_CAEEL HYPOTHETICAL 175.7 KD PROTEIN C05C10.2 IN C... 73 1e-11 pir||T23869 hypothetical protein R03D7.2 - Caenorhabditis elegan... 72 2e-11 pir||S75309 hypothetical protein sll1582 - Synechocystis sp. (st... 72 2e-11 dbj|BAB14299.1| (AK022902) unnamed protein product [Homo sapiens] 72 2e-11 >pir||B75105 probable DNA helicas PAB1561 - Pyrococcus abyssi (strain Orsay) >gi|5458655|emb|CAB50143.1| (AJ248286) DNA helicase, putative [Pyrococcus abyssi] Length = 653 Score = 1279 bits (3274), Expect = 0.0 Identities = 653/653 (100%), Positives = 653/653 (100%) Query: 1 MNITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYFL 60 MNITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYFL Sbjct: 1 MNITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYFL 60 Query: 61 VKYGRNREIKTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWALRDVRI 120 VKYGRNREIKTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWALRDVRI Sbjct: 61 VKYGRNREIKTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWALRDVRI 120 Query: 121 DLYANDITFRRWLENLNTIKKAGKRALRFYLGLDEPSQGEEVNFVPFDKSLNRSQRKAIS 180 DLYANDITFRRWLENLNTIKKAGKRALRFYLGLDEPSQGEEVNFVPFDKSLNRSQRKAIS Sbjct: 121 DLYANDITFRRWLENLNTIKKAGKRALRFYLGLDEPSQGEEVNFVPFDKSLNRSQRKAIS 180 Query: 181 KALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLSRSGIK 240 KALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLSRSGIK Sbjct: 181 KALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLSRSGIK 240 Query: 241 IVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGL 300 IVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGL Sbjct: 241 IVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGL 300 Query: 301 SDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREADV 360 SDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREADV Sbjct: 301 SDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREADV 360 Query: 361 VLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSL 420 VLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSL Sbjct: 361 VLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSL 420 Query: 421 EAQELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRD 480 EAQELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRD Sbjct: 421 EAQELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRD 480 Query: 481 LVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLL 540 LVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLL Sbjct: 481 LVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLL 540 Query: 541 SIGVKPEWIGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIG 600 SIGVKPEWIGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIG Sbjct: 541 SIGVKPEWIGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIG 600 Query: 601 FLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGCFIEFPFS 653 FLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGCFIEFPFS Sbjct: 601 FLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGCFIEFPFS 653 >pir||E71080 probable DNA-binding protein - Pyrococcus horikoshii >gi|3257320|dbj|BAA30003.1| (AP000004) 656aa long hypothetical DNA-binding protein [Pyrococcus horikoshii] Length = 656 Score = 1116 bits (2855), Expect = 0.0 Identities = 563/648 (86%), Positives = 605/648 (92%) Query: 1 MNITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYFL 60 MNI SFINRLKELVEIE+EAEIEAMRLEM+RLSG+ERERLGRAILNLNGKI GEELGYFL Sbjct: 1 MNIKSFINRLKELVEIEKEAEIEAMRLEMKRLSGVERERLGRAILNLNGKIAGEELGYFL 60 Query: 61 VKYGRNREIKTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWALRDVRI 120 VKYGRNREIKTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWALRDVRI Sbjct: 61 VKYGRNREIKTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWALRDVRI 120 Query: 121 DLYANDITFRRWLENLNTIKKAGKRALRFYLGLDEPSQGEEVNFVPFDKSLNRSQRKAIS 180 DLYANDITFRRWLENL+ +KKAGKRAL FYLGLDEPSQGEEV+F PFDKSLN SQRKAI+ Sbjct: 121 DLYANDITFRRWLENLDRVKKAGKRALEFYLGLDEPSQGEEVSFEPFDKSLNSSQRKAIA 180 Query: 181 KALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLSRSGIK 240 K LGSEDFFL+HGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERL++ G+K Sbjct: 181 KGLGSEDFFLIHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLAKDGVK 240 Query: 241 IVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGL 300 IVR+GHPSRVS+HLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGL Sbjct: 241 IVRVGHPSRVSRHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGL 300 Query: 301 SDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREADV 360 SD EIIKLAER+RG RGLSARLI EMAEWIKLNRQVQKAF+DARKLEERIARDIIREADV Sbjct: 301 SDAEIIKLAERRRGIRGLSARLIKEMAEWIKLNRQVQKAFEDARKLEERIARDIIREADV 360 Query: 361 VLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSL 420 +LTTNSSAALEVVD YDVAIIDEATQ+TIPSILIPLNKV+RF+LAGDHKQLPPTILSL Sbjct: 361 ILTTNSSAALEVVDATDYDVAIIDEATQATIPSILIPLNKVDRFILAGDHKQLPPTILSL 420 Query: 421 EAQELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRD 480 EAQELS TLFEGLIERYPWKSEML +QYRMNERIMEFPSKEFY G+I+ADE V+ ITL D Sbjct: 421 EAQELSHTLFEGLIERYPWKSEMLTIQYRMNERIMEFPSKEFYDGRIVADERVKNITLGD 480 Query: 481 LVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLL 540 L + W IL+P NV+VFIDT +N++ERQRRGSESRENPLEA+IV+KIV+KLL Sbjct: 481 LGIKVNATGIWRDILDPSNVLVFIDTCMLDNRFERQRRGSESRENPLEAKIVSKIVEKLL 540 Query: 541 SIGVKPEWIGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIG 600 GVK E IGVITPYDDQRDLIS+ VPE+VEVKTVDGYQGREKEVIILS VRSNK+GEIG Sbjct: 541 ESGVKAEMIGVITPYDDQRDLISLNVPEEVEVKTVDGYQGREKEVIILSFVRSNKVGEIG 600 Query: 601 FLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGCFI 648 FLKDLRRLNVSLTRAKRKLI++GDSSTLSSHETYK++IE +EKG ++ Sbjct: 601 FLKDLRRLNVSLTRAKRKLIMIGDSSTLSSHETYKRLIEHVREKGLYV 648 >pir||G72429 hypothetical protein TM0005 - Thermotoga maritima (strain MSB8) >gi|4980488|gb|AAD35099.1|AE001689_5 (AE001689) DNA helicase, putative [Thermotoga maritima] Length = 650 Score = 792 bits (2022), Expect = 0.0 Identities = 405/651 (62%), Positives = 508/651 (77%), Gaps = 2/651 (0%) Query: 1 MNITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYFL 60 M + FI +L LVE+ER AEI AM EM+RLSG ERE+ GRA+L L GK IGEELGYFL Sbjct: 1 MTVQQFIKKLVRLVELERNAEINAMLDEMKRLSGEEREKKGRAVLGLTGKFIGEELGYFL 60 Query: 61 VKYGRNREIKTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWALRDVRI 120 V++GR ++I TEI VGDLV+ISK +PLKSD GTVVEKG+RFI VA++ +P W L++VRI Sbjct: 61 VRFGRRKKIDTEIGVGDLVLISKGNPLKSDYTGTVVEKGERFITVAVDRLPSWKLKNVRI 120 Query: 121 DLYANDITFRRWLENLNTIKKAGKRALRFYLGLDEPSQGEEVNFVPFDKSLNRSQRKAIS 180 DL+A+DITFRR +ENL T+ GK+AL F LG +P + E F PFD+ LN SQR+A+S Sbjct: 121 DLFASDITFRRQIENLMTLSSEGKKALEFLLGKRKPEESFEEEFTPFDEGLNESQREAVS 180 Query: 181 KALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLSRSGIK 240 ALGS DFFL+HGPFGTGKTRTLVE IRQEV RG K+L TAESN+AVDNLVERL + Sbjct: 181 LALGSSDFFLIHGPFGTGKTRTLVEYIRQEVARGKKILVTAESNLAVDNLVERL-WGKVS 239 Query: 241 IVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGL 300 +VRIGHPSRVS HL E+TLA+ I Y ++++++ L +KRD++TKP+P++RRGL Sbjct: 240 LVRIGHPSRVSSHLKESTLAHQIETSSEYEKVKKMKEELAKLIKKRDSFTKPSPQWRRGL 299 Query: 301 SDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREADV 360 SD++I++ AE+ ARG+S I EMAEWIKLN Q+Q D + EE IA I+REA V Sbjct: 300 SDKKILEYAEKNWSARGVSKEKIKEMAEWIKLNSQIQDIRDLIERKEEIIASRIVREAQV 359 Query: 361 VLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSL 420 VL+TNSSAALE++ +DV ++DEA+Q+TIPSILIP++K ++FVLAGDHKQLPPTILS Sbjct: 360 VLSTNSSAALEILSGIVFDVVVVDEASQATIPSILIPISKGKKFVLAGDHKQLPPTILSE 419 Query: 421 EAQELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRD 480 +A++LSRTLFE LI RYP KS +L QYRMNE +MEFPS+EFY GK+ A E VR ITL D Sbjct: 420 DAKDLSRTLFEELITRYPEKSSLLDTQYRMNELLMEFPSEEFYDGKLKAAEKVRNITLFD 479 Query: 481 L-VEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKL 539 L VE + W +L+P+NV+VFIDT +++ERQR+ S SRENPLEA+IV ++V+KL Sbjct: 480 LGVEIPNFGKFWDVVLSPKNVLVFIDTKNRSDRFERQRKDSPSRENPLEAQIVKEVVEKL 539 Query: 540 LSIGVKPEWIGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNKLGEI 599 LS+GVK +WIG+ITPYDDQ +LI + VEV +VDG+QGREKEVII+S VRSNK GEI Sbjct: 540 LSMGVKEDWIGIITPYDDQVNLIRELIEAKVEVHSVDGFQGREKEVIIISFVRSNKNGEI 599 Query: 600 GFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGCFIEF 650 GFL+DLRRLNVSLTRAKRKLI GDSSTLS H TY++ +EF K+KG ++ F Sbjct: 600 GFLEDLRRLNVSLTRAKRKLIATGDSSTLSVHPTYRRFVEFVKKKGTYVIF 650 >gi|11498984 DNA helicase, putative [Archaeoglobus fulgidus] >gi|7446666|pir||C69423 DNA helicase homolog - Archaeoglobus fulgidus >gi|2649188|gb|AAB89860.1| (AE001009) DNA helicase, putative [Archaeoglobus fulgidus] Length = 648 Score = 737 bits (1881), Expect = 0.0 Identities = 379/644 (58%), Positives = 498/644 (76%), Gaps = 12/644 (1%) Query: 6 FINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYFLVKYGR 65 FI L L E+ER+A+I AM E+RRLSG +RER GRA+L L GK++GEELG+ LV+YGR Sbjct: 4 FIEGLIRLTEVERDAQISAMMDEIRRLSGEKRERKGRAVLGLRGKVVGEELGFKLVRYGR 63 Query: 66 NREIKTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWALRDVRIDLYAN 125 + I+TEISVGD V+IS+ DPLKSDL G VVEKG R++ V+LE+VPEWALRDVRIDLYA+ Sbjct: 64 RKAIETEISVGDEVLISRGDPLKSDLRGVVVEKGSRYLTVSLESVPEWALRDVRIDLYAS 123 Query: 126 DITFRRWLENLNTIKKAGKRALRFYLGLDEPSQGEEVNFVPFDKSLNRSQRKAISKALGS 185 D+TF+RW+ENL + + GKRAL+F LGL+EPS+ E +F PFD SLNR+Q KA+ A+ + Sbjct: 124 DLTFKRWIENLENLTENGKRALKFALGLEEPSKTECEDFKPFDSSLNRAQLKAVGCAVST 183 Query: 186 EDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLSRSGIKIVRIG 245 +DFFL+HGPFGTGKTRT+VE++RQ VKRG +VL TAESN AVDNLVE L S +KIVR+G Sbjct: 184 DDFFLIHGPFGTGKTRTVVEVVRQLVKRGERVLVTAESNTAVDNLVELL--SDMKIVRLG 241 Query: 246 HPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGLSDEEI 305 HPSRV K L E TLA L+ H Y + E++ + + + + TKP+P+ RRGLSDEEI Sbjct: 242 HPSRVEKRLKEHTLASLVLNHPDYKRIEEIKGKIEEIERRMERLTKPSPQLRRGLSDEEI 301 Query: 306 IKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREADVVLTTN 365 ++LA RGARG++A+ I MAEWI+ + + + + + ++ EERI ++II E+DVV++TN Sbjct: 302 LRLARSNRGARGVAAKKIRSMAEWIEARKALDQLYTEMKEEEERIVKEIIEESDVVISTN 361 Query: 366 SSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSLEAQEL 425 SSA L +++D A+IDEA+Q+TIPS+LIP+N+ +F+LAGDH+QLPPT+ ++A++L Sbjct: 362 SSAFLL---EESFDTAVIDEASQATIPSVLIPINRARKFILAGDHRQLPPTV--MKAEKL 416 Query: 426 SRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQ 485 S TLFE LIE YP KS++L VQYRMNE++MEFPS+EFYGG+I+A ES I L + + + Sbjct: 417 SETLFEKLIELYPEKSQLLNVQYRMNEKLMEFPSREFYGGRIVAHESCTAIALSQIAKRE 476 Query: 486 SPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVK 545 + + +IL E +VFIDTSK +N+WE + S SR N LEAEIV +IV +LL +G+K Sbjct: 477 A--EKLREILGDE-PLVFIDTSKCKNRWEGKLADSTSRYNRLEAEIVTEIVTELLKMGLK 533 Query: 546 PEWIGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDL 605 E IGVITPYDDQ DL+ KV DVEV +VDG+QGREKEVII+S VRSN+ EIGFL DL Sbjct: 534 KEQIGVITPYDDQVDLLREKV--DVEVSSVDGFQGREKEVIIISFVRSNRKREIGFLDDL 591 Query: 606 RRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGCFIE 649 RRLNVSLTRA+RKLI+VGDS TLS + TY ++I+ K KG ++E Sbjct: 592 RRLNVSLTRARRKLIMVGDSETLSVNGTYARLIDHVKRKGVYVE 635 >pir||D69085 transcription control factor enhancer-binding protein - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622761|gb|AAB86107.1| (AE000922) transcriptional control factor (enhancer-binding protein) [Methanobacterium thermoautotrophicum] Length = 642 Score = 687 bits (1754), Expect = 0.0 Identities = 363/631 (57%), Positives = 472/631 (74%), Gaps = 6/631 (0%) Query: 16 IEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYFLVKYGRNREIKTEISV 75 +EREAEI AM E+RRLS +RER RA+ LNGKI G ELG+ LVKYGR I T+ISV Sbjct: 1 MEREAEISAMMNEIRRLSPRQRERARRAVNGLNGKITGRELGFHLVKYGRRDPIDTQISV 60 Query: 76 GDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWALRDVRIDLYANDITFRRWLEN 135 GDLV+IS+ +PL+SDL GTV KGKRF+VVALE VP WAL++VRIDLYAND+TF+R ++N Sbjct: 61 GDLVLISRGNPLRSDLTGTVAMKGKRFLVVALEHVPGWALKNVRIDLYANDVTFQRMIDN 120 Query: 136 LNTIKKAGKRALRFYLGLDEPSQGEEV-NFVPFDKSLNRSQRKAISKALGSEDFFLVHGP 194 L + + R L F G ++PS G +V +F D LN SQR AI ALGSEDFFL+HGP Sbjct: 121 LKSPTRNVLRVLGFLCGTEKPSDGVDVVDFQAVDPELNESQRDAIRMALGSEDFFLIHGP 180 Query: 195 FGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKHL 254 FGTGKTRTL ELIRQEV RG++VL TAESN AVDNL+E ++ +K VR+GHP RVS+ Sbjct: 181 FGTGKTRTLHELIRQEVMRGSRVLVTAESNAAVDNLLEGIA-GHVKCVRLGHPQRVSREN 239 Query: 255 HETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRG 314 TLAY I H Y ++RE + L E+R+ + KPTP+ RRGLSD +I+ A ++RG Sbjct: 240 LRETLAYKIENHPEYSKVREYQEKIDELIEERERHQKPTPQIRRGLSDTQILINATKRRG 299 Query: 315 ARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREADVVLTTNSSAALEVVD 374 ARG+S +++ MA WI+ N+++ ++ E RIA I+RE+ VVL+TNSSAALE +D Sbjct: 300 ARGISPNVMISMARWIETNQRIDDLHSKLQEAEMRIADRILRESQVVLSTNSSAALEYID 359 Query: 375 YDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSLEAQELSRTLFEGLI 434 +DVAI+DEA+Q+TIPSILIPL + RF+LAGDH+QLPPTILS +A EL RTLFE LI Sbjct: 360 GLRFDVAIVDEASQATIPSILIPLARAPRFILAGDHRQLPPTILSRDASELERTLFEELI 419 Query: 435 ERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKI 494 +R+P +S ML QYRM+ IMEFP++EFY G+I A S+ I++RD++E +D K+ Sbjct: 420 KRHPGRSRMLNCQYRMHPAIMEFPNREFYDGRIRAHPSLEDISIRDIIEDVPDSDICQKL 479 Query: 495 LNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITP 554 +P+ V+ FIDTS + ER+ +GS S +NPLEA++ I L+ +GVKPE IG+ITP Sbjct: 480 ADPDPVL-FIDTSGLDG-CERRLKGSTSIQNPLEADLAVIISRSLMRMGVKPEEIGIITP 537 Query: 555 YDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTR 614 YDDQ DLIS + DVEV +VDG+QGREK+VII+S+VRSN+ G IGFLKDLRRLNVSLTR Sbjct: 538 YDDQVDLISSMI--DVEVNSVDGFQGREKDVIIISMVRSNRNGSIGFLKDLRRLNVSLTR 595 Query: 615 AKRKLIVVGDSSTLSSHETYKKMIEFFKEKG 645 A+RKLI++GDS TLS+H +Y+++ EF +++G Sbjct: 596 ARRKLIIIGDSRTLSAHPSYRRLTEFCRKRG 626 >sp|Q57568|Y104_METJA HYPOTHETICAL ATP-BINDING PROTEIN MJ0104 >gi|2129217|pir||H64312 probable DNA helicase MJ0104 - Methanococcus jannaschii >gi|1590880|gb|AAB98084.1| (U67467) DNA-binding protein, probably DNA helicase [Methanococcus jannaschii] Length = 663 Score = 540 bits (1377), Expect = e-152 Identities = 298/647 (46%), Positives = 435/647 (67%), Gaps = 23/647 (3%) Query: 6 FINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYFLVKYGR 65 ++ + +L+EIER E++ + E+ +L G +RE +GRAILNL GK +GE LG +V++GR Sbjct: 17 YVKKFMDLIEIERRCEMDFHKNEIIKL-GKKRENVGRAILNLKGKFLGESLGCTIVRFGR 75 Query: 66 NREIKTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALET-VPEWALRD-VRIDLY 123 + KTEIS GD+V++SK +PL+SDL V+ GK FI VA + VP+W ++ VR+DLY Sbjct: 76 KKPFKTEISPGDVVLVSKENPLQSDLYANVIYVGKNFIDVAFDVDVPKWVYKERVRVDLY 135 Query: 124 ANDITFRRWLENLNTIKKAGKRALRFYLGLDEPSQG--EEVNFVPFDKSLNRSQRKAISK 181 NDITF+R E L + + LG++ P + E++ +DK+LN SQ+ A+ K Sbjct: 136 VNDITFKRMKEALREFARKRDKLAYIILGIEHPEKPLREDIKLEFYDKNLNESQKLAVKK 195 Query: 182 ALGSEDFFLVHGPFGTGKTRTLVELIRQEVK-RGNKVLATAESNVAVDNLVERLSRS--G 238 A+ S D +L+HGP GTGKTRT+ E+I QEVK +KVLATA+SN+A DN++E L + Sbjct: 196 AVLSRDLYLIHGPPGTGKTRTITEVIVQEVKFNKHKVLATADSNIAADNILEYLIKKYPD 255 Query: 239 IKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRR 298 +K+VR+GHP+R+SK L + +L YLI HE Y E+ LR + + E+RD + KP+P++RR Sbjct: 256 LKVVRVGHPTRISKDLIQHSLPYLIENHEKYQEILALREKIKEIKEQRDKFLKPSPRWRR 315 Query: 299 GLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREA 358 G+SDE+I+K+A+RK+ RG+ I+ MAEWI N+++++ ++ ++ E+I +I+ EA Sbjct: 316 GMSDEQILKVAKRKKSYRGIPKEKIVSMAEWIIRNKKIKRIINNLDEITEKIMNEILAEA 375 Query: 359 DVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTIL 418 DV++ TNS A E++ +DV +IDE +Q+ PS LIP+ K + ++AGDHKQLPPT+L Sbjct: 376 DVIVATNSMAGSEILKGWEFDVIVIDEGSQAMEPSCLIPIVKGRKLIMAGDHKQLPPTVL 435 Query: 419 SLEAQELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITL 478 S E +EL +TLFE LI++YP S +L +QYRMNE+IMEFP+K FY K+ ADESV+ ITL Sbjct: 436 S-ENEELKKTLFERLIKKYPEFSSILEIQYRMNEKIMEFPNKMFYNNKLKADESVKNITL 494 Query: 479 RDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDK 538 DLV+ + ++ I+N E + FI+ ER+ + S S N EAE V +IV K Sbjct: 495 LDLVKEEEIDEVDRDIIN-EIPVQFINVEGI----ERKDKESPSYYNIEEAEKVLEIVKK 549 Query: 539 LLSIGVKPEWIGVITPYDDQRDLISMKVPE---DVEVKTVDGYQGREKEVIILSLVRSNK 595 L+ + VITPYD Q + E D+EV TVDG+QGRE E I++S VR+ Sbjct: 550 LVKYKIP---TNVITPYDAQVRYLRRLFEEHNIDIEVNTVDGFQGRENEAIVISFVRTK- 605 Query: 596 LGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFK 642 GFLKDLRRLNV++TRAKRKLI++G+ + L + Y +MI++ K Sbjct: 606 --NFGFLKDLRRLNVAITRAKRKLILIGNENLLKQDKVYNEMIKWAK 650 >pir||D70476 DNA helicase - Aquifex aeolicus >gi|2984278|gb|AAC07803.1| (AE000770) DNA helicase [Aquifex aeolicus] Length = 530 Score = 461 bits (1174), Expect = e-129 Identities = 251/484 (51%), Positives = 342/484 (69%), Gaps = 10/484 (2%) Query: 171 LNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNL 230 LN Q+KA+ +AL +E FL+HGP GTGKT TLVE I++ + G KVLATA+SNVAVDNL Sbjct: 49 LNAYQKKAVERALKAEKVFLIHGPPGTGKTTTLVECIKRLAQEGYKVLATADSNVAVDNL 108 Query: 231 VERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYT 290 VERL R +K+VR+G+P RV K + TL YL+ + + R++ +L E++ Y Sbjct: 109 VERLVRENVKVVRVGNPVRVLKTIQRHTLDYLVQFEPEFDKARKIYEEIDNLKEEQKKYV 168 Query: 291 KPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERI 350 KP P++RRGLSDEEI+K A+ RGLS +++ MA+WIKL +V++ ++ A+K EE+ Sbjct: 169 KPEPRYRRGLSDEEILKRAKTGTPVRGLSPKILRSMAKWIKLQEKVKELYEKAKKEEEKA 228 Query: 351 ARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDH 410 I+ A VV TTNS+A EV+ +DV IIDEATQ+T PS LIPL K ++ ++AGDH Sbjct: 229 VNKILSRAQVVCTTNSTAGSEVLQNLNFDVVIIDEATQATEPSCLIPLIKGKKLIMAGDH 288 Query: 411 KQLPPTILSLEAQE-LSRTLFEGLIERYPWK-SEMLVVQYRMNERIMEFPSKEFYGGKII 468 KQLPPT+LS EAQE LS TLFE L++ Y + E+L +QYRMN++IMEF +K FY GK+I Sbjct: 289 KQLPPTVLSQEAQEALSYTLFERLLDLYGEEIYEILRIQYRMNKKIMEFSNKMFYEGKLI 348 Query: 469 ADESVRGITLRDLV---EYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESREN 525 AD+SV T++DL+ + + + + +L PE V+VFI+ E+QRRGS S N Sbjct: 349 ADKSVENHTIKDLINPEKLKEIPEPFKSVLEPEKVVVFINVRGK----EKQRRGSTSFYN 404 Query: 526 PLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE-DVEVKTVDGYQGREKE 584 EA++ KIV+ L+ IG++ E IGVI+PY+DQ + + + + +VEVKTVDG+QGREKE Sbjct: 405 EEEAKVAVKIVEYLMKIGLRSEHIGVISPYEDQVNFLEELLKDFEVEVKTVDGFQGREKE 464 Query: 585 VIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEK 644 VII+S VRSN+ GEIGFLKD RRLNV+LTRA+RKLI +G+ TLSS E YK+ I + K Sbjct: 465 VIIISFVRSNEKGEIGFLKDYRRLNVALTRARRKLITLGNEKTLSSDEVYKQFIGYVKSI 524 Query: 645 GCFI 648 G +I Sbjct: 525 GGYI 528 >pir||T02699 hypothetical protein T18E12.6 - Arabidopsis thaliana >gi|4335770|gb|AAD17447.1| (AC006284) putative helicase [Arabidopsis thaliana] Length = 635 Score = 352 bits (894), Expect = 6e-96 Identities = 249/672 (37%), Positives = 377/672 (56%), Gaps = 68/672 (10%) Query: 1 MNITSFINRLKELVEIEREAEIEAMRLEMRRLSGIER-ERLGRAILNLNGKIIGEEL-GY 58 M++ +F++ + L+++E+EAEI +M L IE ++ G ILNL + L G Sbjct: 1 MSLEAFVSTMAPLIDMEKEAEI-SMSLTSGASRNIETAQKKGTTILNLKCVDVQTGLMGK 59 Query: 59 FLVKYGRNR-EIKTEISVG--DLVVI--SKRDPLKSDLLGTVVEKGK-RFIVVALETVPE 112 L+++ N+ ++ G D+VV+ +K D S L VV + K I V + VPE Sbjct: 60 SLIEFQSNKGDVLPAHKFGNHDVVVLKLNKSDLGSSPLAQGVVYRLKDSSITVVFDEVPE 119 Query: 113 WALR-DVRIDLYANDITFRRWLENLNTIKKAGKRA-----LRFYLGLDEPSQGEE--VNF 164 L +R++ AN++T+RR + L + K R + G +PS ++ +F Sbjct: 120 EGLNTSLRLEKLANEVTYRRMKDTLIQLSKGVLRGPASDLVPVLFGERQPSVSKKDVKSF 179 Query: 165 VPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESN 224 PF+K+L++SQ+ AI+KAL S+D FL+HGP GTGKT T+VE++ QEVKRG+K+LA A SN Sbjct: 180 TPFNKNLDQSQKDAITKALSSKDVFLLHGPPGTGKTTTVVEIVLQEVKRGSKILACAASN 239 Query: 225 VAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAE 284 +AVDN+VERL +K+VR+GHP+R+ + ++ L + + + G ++R ++L Sbjct: 240 IAVDNIVERLVPHKVKLVRVGHPARLLPQVLDSALDAQVLKGDNSGLANDIRKEMKALNG 299 Query: 285 KRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDAR 344 K K K R L +E+ L + + R Sbjct: 300 K---LLKAKDKNTRRLIQKELRTLGK-------------------------------EER 325 Query: 345 KLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERF 404 K ++ D+I+ ADV+LTT + A +D T+D+ IIDE Q+ + I L K R Sbjct: 326 KRQQLAVSDVIKNADVILTTLTGALTRKLDNRTFDLVIIDEGAQALEVACWIALLKGSRC 385 Query: 405 VLAGDHKQLPPTILSLEAQE--LSRTLFEGLIERYPWK-SEMLVVQYRMNERIMEFPSKE 461 +LAGDH QLPPTI S EA+ L RTLFE L + Y + ML VQYRM+E IM + SKE Sbjct: 386 ILAGDHLQLPPTIQSAEAERKGLGRTLFERLADLYGDEIKSMLTVQYRMHELIMNWSSKE 445 Query: 462 FYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSE 521 Y KI A SV L DL ++ K + E ++ +DT+ + E ++ E Sbjct: 446 LYDNKITAHSSVASHMLFDL-------ENVTKSSSTEATLLLVDTAGCD--MEEKKDEEE 496 Query: 522 SRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISM-----KVPEDVEVKTVD 576 S N EAE+ +L+ GV+P IG+ITPY Q L+ + + +D+E+ TVD Sbjct: 497 STYNEGEAEVAMAHAKRLMESGVQPSDIGIITPYAAQVMLLRILRGKEEKLKDMEISTVD 556 Query: 577 GYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKK 636 G+QGREKE II+S+VRSN E+GFLKD RR+NV++TR++R+ +V D+ T+SS K+ Sbjct: 557 GFQGREKEAIIISMVRSNSKKEVGFLKDQRRMNVAVTRSRRQCCIVCDTETVSSDAFLKR 616 Query: 637 MIEFFKEKGCFI 648 MIE+F+E G ++ Sbjct: 617 MIEYFEEHGEYL 628 >emb|CAC16347.1| (AJ300306) putative helicase [Arabidopsis thaliana] Length = 635 Score = 351 bits (891), Expect = 1e-95 Identities = 248/672 (36%), Positives = 375/672 (54%), Gaps = 68/672 (10%) Query: 1 MNITSFINRLKELVEIEREAEIEAMRLEMRRLSGIER-ERLGRAILNLNGKIIGEEL-GY 58 M++ +F++ + L+++E+EAEI +M L IE ++ G ILNL + L G Sbjct: 1 MSLEAFVSTMAPLIDMEKEAEI-SMSLTSGASRNIETAQKKGTTILNLKCVDVQTGLMGK 59 Query: 59 FLVKYGRNREIKT---EISVGDLVVI--SKRDPLKSDLLGTVVEKGK-RFIVVALETVPE 112 L+++ N+ + D+VV+ +K D S L VV + K I V + VPE Sbjct: 60 SLIEFQSNKGDALPAHKFGNHDVVVLKLNKSDLGSSPLAQGVVYRLKDSSITVVFDEVPE 119 Query: 113 WALR-DVRIDLYANDITFRRWLENLNTIKKAGKRA-----LRFYLGLDEPSQGEE--VNF 164 L +R++ AN++T+RR + L + K R + G +PS ++ +F Sbjct: 120 EGLNTSLRLEKLANEVTYRRMKDTLIQLSKGVLRGPASDLVPVLFGERQPSVSKKDVKSF 179 Query: 165 VPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESN 224 PF+K+L++SQ+ AI+KAL S+D FL+HGP GTGKT T+VE++ QEVKRG+K+LA A SN Sbjct: 180 TPFNKNLDQSQKDAITKALSSKDVFLLHGPPGTGKTTTVVEIVLQEVKRGSKILACAASN 239 Query: 225 VAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAE 284 +AVDN+VERL +K+VR+GHP+R+ + ++ L + + + G ++R ++L Sbjct: 240 IAVDNIVERLVPHKVKLVRVGHPARLLPQVLDSALDAQVLKGDNSGLANDIRKEMKALNG 299 Query: 285 KRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDAR 344 K K K R L +E+ L + + R Sbjct: 300 K---LLKAKDKNTRRLIQKELRTLGK-------------------------------EER 325 Query: 345 KLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERF 404 K ++ D+I+ ADV+LTT + A +D T+D+ IIDE Q+ + I L K R Sbjct: 326 KRQQLAVSDVIKNADVILTTLTGALTRKLDNRTFDLVIIDEGAQALEVACWIALLKGSRC 385 Query: 405 VLAGDHKQLPPTILSLEAQE--LSRTLFEGLIERYPWK-SEMLVVQYRMNERIMEFPSKE 461 +LAGDH QLPPTI S EA+ L RTLFE L + Y + ML VQYRM+E IM + SKE Sbjct: 386 ILAGDHLQLPPTIQSAEAERKGLGRTLFERLADLYGDEIKSMLTVQYRMHELIMNWSSKE 445 Query: 462 FYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSE 521 Y KI A SV L DL ++ K + E ++ +DT+ + E ++ E Sbjct: 446 LYDNKITAHSSVASHMLFDL-------ENVTKSSSTEATLLLVDTAGCD--MEEKKDEEE 496 Query: 522 SRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISM-----KVPEDVEVKTVD 576 S N EAE+ +L+ GV+P IG+ITPY Q L+ + + +D+E+ TVD Sbjct: 497 STYNEGEAEVAMAHAKRLMESGVQPSDIGIITPYAAQVMLLRILRGKEEKLKDMEISTVD 556 Query: 577 GYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKK 636 G+QGREKE II+S+VRSN E+GFLKD RR+NV++TR++R+ +V D+ T+SS K+ Sbjct: 557 GFQGREKEAIIISMVRSNSKKEVGFLKDQRRMNVAVTRSRRQCCIVCDTETVSSDAFLKR 616 Query: 637 MIEFFKEKGCFI 648 MIE+F+E G ++ Sbjct: 617 MIEYFEEHGEYL 628 >gb|AAG28561.1|AF199411_1 (AF199411) antifreeze-enhancer binding protein AEP [Rattus norvegicus] Length = 988 Score = 300 bits (760), Expect = 3e-80 Identities = 225/676 (33%), Positives = 360/676 (52%), Gaps = 81/676 (11%) Query: 3 ITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYF--- 59 + SF+ + +L+E+ER+AE+E R S E + G +L L ++ G+ G + Sbjct: 6 VESFVAQQLQLLELERDAEVEERRSWQEHSSLKELQSRGVCLLKL--QVSGQRTGLYGQR 63 Query: 60 LV-----KYGRNREIKTE-ISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEW 113 LV K+G + + + GD+V + + G + ++ ++VA + ++ Sbjct: 64 LVTFEPRKFGPAVVLPSNSFTSGDIVGLYDTNESSQLATGVLTRITQKSVIVAFDESHDF 123 Query: 114 ALRDVRIDLY-----ANDITFRRWLENLNTIKK----AGKRALRFYLGLDEPSQGEEVNF 164 L R + Y AND+T++R + L T+KK + LG PS E+ Sbjct: 124 QLNLDRENTYRLLKLANDVTYKRLKKALLTLKKYHSGPASSLIDVLLGGSTPSPATEIPP 183 Query: 165 VPF-DKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAES 223 + F + +L+ SQ++A+S AL ++ ++HGP GTGKT T+VE+I Q VK+G KVL A S Sbjct: 184 LTFYNTTLDPSQKEAVSFALAQKEVAIIHGPPGTGKTTTVVEIILQAVKQGLKVLCCAPS 243 Query: 224 NVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQH---ELYGELRELRVIGQ 280 N+AVDNLVERL+ +I+R+GHP+R+ + + + +L ++ + ++ ++R R I Q Sbjct: 244 NIAVDNLVERLALCKKQILRLGHPARLLESVQQHSLDAVLARSDNAQIVADIR--RDIDQ 301 Query: 281 SLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAF 340 + + T K R + IKL + Sbjct: 302 VFGKNKKTQDK-----REKSNFRNEIKLLRK----------------------------- 327 Query: 341 DDARKLEERIARDIIREADVVLTTNSSAA----LEVVDYDTYDVAIIDEATQSTIPSILI 396 + ++ EE + ADVVL TN+ A+ L+++ D +DV ++DE Q+ S I Sbjct: 328 -ELKEREEAAIVQSLSAADVVLATNTGASTDGPLKLLPEDYFDVVVVDECAQALEASCWI 386 Query: 397 PLNKVERFVLAGDHKQLPPTILSLEA--QELSRTLFEGLIERY-PWKSEMLVVQYRMNER 453 PL K + +LAGDHKQLPPT +S +A LSR+L E L E++ ML VQYRM++ Sbjct: 387 PLLKAPKCILAGDHKQLPPTTVSHKAALAGLSRSLMERLAEKHGAAVVRMLAVQYRMHQA 446 Query: 454 IMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKW 513 I + S+ Y G++ A SV G L+DL ++ +L IDT+ Sbjct: 447 ITRWASEAMYHGQLTAHPSVAGHLLKDLPGVADTEETSVPLL-------LIDTAGC-GLL 498 Query: 514 ERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDL----ISMKVPED 569 E + S+S+ NP E +V + L+ GV+ I VI PY+ Q DL +S K PE Sbjct: 499 ELEEEDSQSKGNPGEVRLVTLHIQALVDAGVQAGDIAVIAPYNLQVDLLRQSLSNKHPE- 557 Query: 570 VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLS 629 +E+K+VDG+QGREKE +IL+ VRSN+ GE+GFL + RR+NV++TRA+R + V+ DS T++ Sbjct: 558 LEIKSVDGFQGREKEAVILTFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSHTVN 617 Query: 630 SHETYKKMIEFFKEKG 645 +H K ++++F E G Sbjct: 618 NHAFLKTLVDYFTEHG 633 >gi|4504623 immunoglobulin mu binding protein 2 [Homo sapiens] >gi|730751|sp|P38935|SMB2_HUMAN DNA-BINDING PROTEIN SMUBP-2 (IMMUNOGLOBULIN MU BINDING PROTEIN 2) (SMUBP-2) (GLIAL FACTOR-1) (GF-1) >gi|401776|gb|AAA53082.1| (L14754) DNA-binding protein [Homo sapiens] Length = 993 Score = 299 bits (757), Expect = 7e-80 Identities = 221/677 (32%), Positives = 357/677 (52%), Gaps = 82/677 (12%) Query: 3 ITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYF--- 59 + SF+ + +L+E+ER+AE+E R +S E + G +L L ++ + G + Sbjct: 6 VESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKL--QVSSQRTGLYGRL 63 Query: 60 LV-----KYGRNREIKTE-ISVGDLVVI----SKRDPLKSDLLGTVVEKGKRFIVVALET 109 LV +YG + + + GD+V + ++ L + +L V +K + VA + Sbjct: 64 LVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKS---VTVAFDE 120 Query: 110 VPEWALRDVRIDLY-----ANDITFRRWLENLNTIKK----AGKRALRFYLGLDEPSQGE 160 ++ L R + Y AND+T+RR + L +KK + G PS Sbjct: 121 SHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPAS 180 Query: 161 EVNFVPF-DKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLA 219 E++ + F + L+ SQ++A+S AL ++ ++HGP GTGKT T+VE+I Q VK+G KVL Sbjct: 181 EIHPLTFFNTCLDTSQKEAVSFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLC 240 Query: 220 TAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRV-I 278 A SN+AVDNLVERL+ +I+R+GHP+R+ + + + +L ++ + + + ++R I Sbjct: 241 CAPSNIAVDNLVERLALCKQRILRLGHPARLLESVQQHSLDAVLARSDSAQNVADIRKDI 300 Query: 279 GQSLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQK 338 Q + + T K R IKL R+ K Sbjct: 301 DQVFVKNKKTQDK-----------------------------REKSNFRNEIKLLRKELK 331 Query: 339 AFDDARKLEERIARDIIREADVVLTTNSSAA----LEVVDYDTYDVAIIDEATQSTIPSI 394 ++A LE + A+VVL TN+ A+ L+++ +DV +IDE Q+ S Sbjct: 332 EREEAAMLES------LTSANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASC 385 Query: 395 LIPLNKVERFVLAGDHKQLPPTILSLEA--QELSRTLFEGLIERYPWK-SEMLVVQYRMN 451 IPL K + +LAGDHKQLPPT +S +A LS +L E L E Y + L VQYRM+ Sbjct: 386 WIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLAEEYGARVVRTLTVQYRMH 445 Query: 452 ERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAEN 511 + IM + S Y G++ A SV LRDL + ++ +L +DT+ Sbjct: 446 QAIMRWASDTMYLGQVTAHSSVARHLLRDLPGVAATEETGVPLL-------LVDTAGC-G 497 Query: 512 KWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE--- 568 +E + +S+ NP E +V+ + L+ GV I V++PY+ Q DL+ + Sbjct: 498 LFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRHP 557 Query: 569 DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL 628 ++E+K+VDG+QGREKE +ILS VRSN+ GE+GFL + RR+NV++TRA+R + V+ DS T+ Sbjct: 558 ELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTV 617 Query: 629 SSHETYKKMIEFFKEKG 645 ++H K ++E+F + G Sbjct: 618 NNHAFLKTLVEYFTQHG 634 >pir||A47500 Ig mu chain switch region binding protein 2 - human Length = 993 Score = 299 bits (757), Expect = 7e-80 Identities = 221/677 (32%), Positives = 357/677 (52%), Gaps = 82/677 (12%) Query: 3 ITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYF--- 59 + SF+ + +L+E+ER+AE+E R +S E + G +L L ++ + G + Sbjct: 6 VESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKL--QVSSQRTGLYGRL 63 Query: 60 LV-----KYGRNREIKTE-ISVGDLVVI----SKRDPLKSDLLGTVVEKGKRFIVVALET 109 LV +YG + + + GD+V + ++ L + +L V +K + VA + Sbjct: 64 LVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKS---VTVAFDE 120 Query: 110 VPEWALRDVRIDLY-----ANDITFRRWLENLNTIKK----AGKRALRFYLGLDEPSQGE 160 ++ L R + Y AND+T+RR + L +KK + G PS Sbjct: 121 SHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPAS 180 Query: 161 EVNFVPF-DKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLA 219 E++ + F + L+ SQ++A+S AL ++ ++HGP GTGKT T+VE+I Q VK+G KVL Sbjct: 181 EIHPLTFFNTCLDTSQKEAVSFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLC 240 Query: 220 TAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRV-I 278 A SN+AVDNLVERL+ +I+R+GHP+R+ + + + +L ++ + + + ++R I Sbjct: 241 CAPSNIAVDNLVERLALCKQRILRLGHPARLLESVQQHSLDAVLARSDSAQNVADIRKDI 300 Query: 279 GQSLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQK 338 Q + + T K R IKL R+ K Sbjct: 301 DQVFVKNKKTQDK-----------------------------REKSNFRNEIKLLRKELK 331 Query: 339 AFDDARKLEERIARDIIREADVVLTTNSSAA----LEVVDYDTYDVAIIDEATQSTIPSI 394 ++A LE + A+VVL TN+ A+ L+++ +DV +IDE Q+ S Sbjct: 332 EREEAAMLES------LTSANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASC 385 Query: 395 LIPLNKVERFVLAGDHKQLPPTILSLEA--QELSRTLFEGLIERYPWK-SEMLVVQYRMN 451 IPL K + +LAGDHKQLPPT +S +A LS +L E L E Y + L VQYRM+ Sbjct: 386 WIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLAEEYGARVVRTLTVQYRMH 445 Query: 452 ERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAEN 511 + IM + S Y G++ A SV LRDL + ++ +L +DT+ Sbjct: 446 QAIMRWASDTMYLGQVTAHSSVARHLLRDLPGVAATEETGVPLL-------LVDTAGC-G 497 Query: 512 KWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE--- 568 +E + +S+ NP E +V+ + L+ GV I V++PY+ Q DL+ + Sbjct: 498 LFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRHP 557 Query: 569 DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL 628 ++E+K+VDG+QGREKE +ILS VRSN+ GE+GFL + RR+NV++TRA+R + V+ DS T+ Sbjct: 558 ELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTV 617 Query: 629 SSHETYKKMIEFFKEKG 645 ++H K ++E+F + G Sbjct: 618 NNHAFLKTLVEYFTQHG 634 >gi|11435569 immunoglobulin mu binding protein 2 [Homo sapiens] Length = 731 Score = 298 bits (754), Expect = 2e-79 Identities = 221/677 (32%), Positives = 357/677 (52%), Gaps = 82/677 (12%) Query: 3 ITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYF--- 59 + SF+ + +L+E+ER+AE+E R +S E + G +L L ++ + G + Sbjct: 6 VESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKL--QVSSQRTGLYGRL 63 Query: 60 LV-----KYGRNREIKTE-ISVGDLVVI----SKRDPLKSDLLGTVVEKGKRFIVVALET 109 LV +YG + + + GD+V + ++ L + +L V +K + VA + Sbjct: 64 LVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKS---VTVAFDE 120 Query: 110 VPEWALRDVRIDLY-----ANDITFRRWLENLNTIKK----AGKRALRFYLGLDEPSQGE 160 ++ L R + Y AND+T+RR + L +KK + G PS Sbjct: 121 SHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPAS 180 Query: 161 EVNFVPF-DKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLA 219 E++ + F + L+ SQ++A+S AL ++ ++HGP GTGKT T+VE+I Q VK+G KVL Sbjct: 181 EIHPLTFFNTCLDTSQKEAVSFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLC 240 Query: 220 TAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRV-I 278 A SN+AVDNLVERL+ +I+R+GHP+R+ + + + +L ++ + + + ++R I Sbjct: 241 CAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDI 300 Query: 279 GQSLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQK 338 Q + + T K R IKL R+ K Sbjct: 301 DQVFVKNKKTQDK-----------------------------REKSNFRNEIKLLRKELK 331 Query: 339 AFDDARKLEERIARDIIREADVVLTTNSSAA----LEVVDYDTYDVAIIDEATQSTIPSI 394 ++A LE + A+VVL TN+ A+ L+++ +DV +IDE Q+ S Sbjct: 332 EREEAAMLES------LTSANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASC 385 Query: 395 LIPLNKVERFVLAGDHKQLPPTILSLEA--QELSRTLFEGLIERYPWK-SEMLVVQYRMN 451 IPL K + +LAGDHKQLPPT +S +A LS +L E L E Y + L VQYRM+ Sbjct: 386 WIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLAEEYGARVVRTLTVQYRMH 445 Query: 452 ERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAEN 511 + IM + S Y G++ A SV LRDL + ++ +L +DT+ Sbjct: 446 QAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATEETGVPLL-------LVDTAGC-G 497 Query: 512 KWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE--- 568 +E + +S+ NP E +V+ + L+ GV I V++PY+ Q DL+ + Sbjct: 498 LFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRHP 557 Query: 569 DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL 628 ++E+K+VDG+QGREKE +ILS VRSN+ GE+GFL + RR+NV++TRA+R + V+ DS T+ Sbjct: 558 ELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTV 617 Query: 629 SSHETYKKMIEFFKEKG 645 ++H K ++E+F + G Sbjct: 618 NNHAFLKTLVEYFTQHG 634 >sp|Q60560|SMB2_MESAU DNA-BINDING PROTEIN SMUBP-2 (IMMUNOGLOBULIN MU BINDING PROTEIN 2) (SMUBP-2) (INSULIN II GENE ENHANCER-BINDING PROTEIN) (RIPE3B-BINDING COMPLEX 3B2 P110 SUBUNIT) (RIP-1) >gi|11360343|pir||T48845 insulin II gene enhancer-binding protein rip1 [validated] - golden hamster >gi|290919|gb|AAB00104.1| (L15625) insulin II gene enhancer-binding protein [Mesocricetus auratus] Length = 989 Score = 296 bits (750), Expect = 5e-79 Identities = 223/678 (32%), Positives = 353/678 (51%), Gaps = 85/678 (12%) Query: 3 ITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYFLVK 62 + SF+ + EL+E+ER+AE+E R S E + G +L L ++ + G Sbjct: 6 VESFVAQQLELLELERDAEVEERRSWQEHSSLKELQSRGVCLLKL--QVSSQCTGL---- 59 Query: 63 YGRNREIKTEISVGDLVVISKRDPLKSDLLG-------------TVVEKGKRFIVVALET 109 YG+ +G +VV+ D++G + ++ + VA + Sbjct: 60 YGQRLVTFEPRKLGPVVVLPSNSFTSGDIVGLYDANESSQLATGVLTRITQKSVTVAFDE 119 Query: 110 VPEWALRDVRIDLY-----ANDITFRRWLENLNTIKK----AGKRALRFYLGLDEPSQGE 160 ++ L R + Y AND+T++R + L T+KK + LG PS Sbjct: 120 SHDFQLNLDRENTYRLLKLANDVTYKRLKKALMTLKKYHSGPASSLIDVLLGGSSPSPTT 179 Query: 161 EVN-FVPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLA 219 E+ F ++ +L+ SQ++A+S AL ++ ++HGP GTGKT T+VE+I Q VK+G K+L Sbjct: 180 EIPPFTFYNTALDPSQKEAVSFALAQKEVAIIHGPPGTGKTTTVVEIILQAVKQGLKILC 239 Query: 220 TAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRV-I 278 A SNVAVDNLVERL+ +I+R+GHP+R+ + + +L ++ + + + ++R I Sbjct: 240 CAPSNVAVDNLVERLALCKKRILRLGHPARLLESAQQHSLDAVLARSDNAQIVADIRKDI 299 Query: 279 GQSLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQK 338 Q + + T K R IKL R+ K Sbjct: 300 DQVFGKNKKTQDK-----------------------------REKSNFRNEIKLLRKELK 330 Query: 339 AFDDARKLEERIARDIIREADVVLTTNSSAA----LEVVDYDTYDVAIIDEATQSTIPSI 394 ++A ++ A ADVVL TN+ A+ L+++ + +DV ++DE Q+ S Sbjct: 331 EREEAAIVQSLTA------ADVVLATNTGASSDGPLKLLPENHFDVVVVDECAQALEASC 384 Query: 395 LIPLNKVERFVLAGDHKQLPPTILSLEA--QELSRTLFEGLIERY-PWKSEMLVVQYRMN 451 IPL K + +LAGDH+QLPPT +S +A LSR+L E L+E++ ML VQYRM+ Sbjct: 385 WIPLLKAPKCILAGDHRQLPPTTISHKAALAGLSRSLMERLVEKHGAGAVRMLTVQYRMH 444 Query: 452 ERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAEN 511 + I + S+ Y G++ A SV G L+DL ++ +L IDT+ Sbjct: 445 QAITRWASEAMYHGQLTAHPSVAGHLLKDLPGVADTEETSVPLL-------LIDTAGC-G 496 Query: 512 KWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDL----ISMKVP 567 E S+S+ NP E +V + L+ GV I VI PY+ Q DL +S K P Sbjct: 497 LLELDEEDSQSKGNPGEVRLVTLHIQALVDAGVHAGDIAVIAPYNLQVDLLRQSLSNKHP 556 Query: 568 EDVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSST 627 E +E+K+VDG+QGREKE +IL+ VRSN+ GE+GFL + RR+NV++TRA+R + V+ DS T Sbjct: 557 E-LEIKSVDGFQGREKEAVILTFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRT 615 Query: 628 LSSHETYKKMIEFFKEKG 645 +++H K ++++F E G Sbjct: 616 VNNHAFLKTLVDYFTEHG 633 >gb|AAA70430.1| (L24544) DNA helicase [Homo sapiens] Length = 993 Score = 295 bits (748), Expect = 8e-79 Identities = 220/677 (32%), Positives = 356/677 (52%), Gaps = 82/677 (12%) Query: 3 ITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYF--- 59 + SF+ + +L+E+ER+AE+E R +S E + G +L L ++ + G + Sbjct: 6 VESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKL--QVSSQRTGLYGRL 63 Query: 60 LV-----KYGRNREIKTE-ISVGDLVVI----SKRDPLKSDLLGTVVEKGKRFIVVALET 109 LV +YG + + + GD+V + ++ L + +L V +K + VA + Sbjct: 64 LVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKS---VTVAFDE 120 Query: 110 VPEWALRDVRIDLY-----ANDITFRRWLENLNTIKK----AGKRALRFYLGLDEPSQGE 160 ++ L R + Y AND+T+RR + L +KK + G PS Sbjct: 121 SHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPAS 180 Query: 161 EVNFVPF-DKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLA 219 E++ + F + L+ SQ++A+ AL ++ ++HGP GTGKT T+VE+I Q VK+G KVL Sbjct: 181 EIHPLTFFNTCLDTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLC 240 Query: 220 TAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRV-I 278 A SN+AVDNLVERL+ +I+R+GHP+R+ + + + +L ++ + + + ++R I Sbjct: 241 CAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDI 300 Query: 279 GQSLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQK 338 Q + + T K R IKL R+ K Sbjct: 301 DQVFVKNKKTQDK-----------------------------REKSNFRNEIKLLRKELK 331 Query: 339 AFDDARKLEERIARDIIREADVVLTTNSSAA----LEVVDYDTYDVAIIDEATQSTIPSI 394 ++A LE + A+VVL TN+ A+ L+++ +DV +IDE Q+ S Sbjct: 332 EREEAAMLES------LTSANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASC 385 Query: 395 LIPLNKVERFVLAGDHKQLPPTILSLEA--QELSRTLFEGLIERYPWK-SEMLVVQYRMN 451 IPL K + +LAGDHKQLPPT +S +A LS +L E L E Y + L VQYRM+ Sbjct: 386 WIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLAEEYGARVVRTLTVQYRMH 445 Query: 452 ERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAEN 511 + IM + S Y G++ A SV LRDL + ++ +L +DT+ Sbjct: 446 QAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATEETGVPLL-------LVDTAGC-G 497 Query: 512 KWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE--- 568 +E + +S+ NP E +V+ + L+ GV I V++PY+ Q DL+ + Sbjct: 498 LFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRHP 557 Query: 569 DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL 628 ++E+K+VDG+QGREKE +ILS VRSN+ GE+GFL + RR+NV++TRA+R + V+ DS T+ Sbjct: 558 ELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTV 617 Query: 629 SSHETYKKMIEFFKEKG 645 ++H K ++E+F + G Sbjct: 618 NNHAFLKTLVEYFTQHG 634 >gi|6678029 immunoglobulin S mu binding protein 2 [Mus musculus] >gi|730752|sp|P40694|SMB2_MOUSE DNA-BINDING PROTEIN SMUBP-2 (IMMUNOGLOBULIN MU BINDING PROTEIN 2) (SMUBP-2) (CARDIAC TRANSCRIPTION FACTOR 1) (CATF1) >gi|423421|pir||S35633 DNA-binding protein - mouse >gi|293806|gb|AAA40143.1| (L10075) DNA-binding protein [Mus musculus] Length = 993 Score = 294 bits (746), Expect = 1e-78 Identities = 224/674 (33%), Positives = 357/674 (52%), Gaps = 77/674 (11%) Query: 3 ITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGK-----IIGEELG 57 + SF+ + +L+E+ER+AE+E R S E + G +L L + G+ L Sbjct: 6 VESFVAQQLQLLELERDAEVEERRSWQEHSSLRELQSRGVCLLKLQVSSQRTGLYGQRLV 65 Query: 58 YFLV-KYGRNREIKTE-ISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWAL 115 F K+G + + + GD+V + + G + ++ + VA + + L Sbjct: 66 TFEPRKFGPAVVLPSNSFTSGDIVGLYDTNENSQLATGVLTRITQKSVTVAFDESHDLQL 125 Query: 116 RDVRIDLY-----ANDITFRRWLENLNTIKK----AGKRALRFYLGLDEPSQGEEVNFVP 166 R + Y AND+T++R + L T+KK + LG PS E+ + Sbjct: 126 NLDRENTYRLLKLANDVTYKRLKKALMTLKKYHSGPASSLIDILLGSSTPSPAMEIPPLS 185 Query: 167 F-DKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNV 225 F + +L+ SQ++A+S AL ++ ++HGP GTGKT T+VE+I Q VK+G KVL A SN+ Sbjct: 186 FYNTTLDLSQKEAVSFALAQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLCCAPSNI 245 Query: 226 AVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQH---ELYGELRELRVIGQSL 282 AVDNLVERL+ +I+R+GHP+R+ + + +L ++ + ++ ++R R I Q Sbjct: 246 AVDNLVERLALCKKRILRLGHPARLLESVQHHSLDAVLARSDNAQIVADIR--RDIDQVF 303 Query: 283 AEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDD 342 + + T K R++G IKL R+ K ++ Sbjct: 304 GKNKKTQDK-------------------REKG----------NFRSEIKLLRKELKEREE 334 Query: 343 ARKLEERIARDIIREADVVLTTNSSAA----LEVVDYDTYDVAIIDEATQSTIPSILIPL 398 A ++ A ADVVL TN+ A+ L+++ D +DV ++DE Q+ S IPL Sbjct: 335 AAIVQSLTA------ADVVLATNTGASSDGPLKLLPEDYFDVVVVDECAQALEASCWIPL 388 Query: 399 NKVERFVLAGDHKQLPPTILSLEA--QELSRTLFEGLIERY-PWKSEMLVVQYRMNERIM 455 K + +LAGDH+QLPPT +S A LSR+L E L E++ ML VQYRM++ IM Sbjct: 389 LKAPKCILAGDHRQLPPTTVSHRAALAGLSRSLMERLAEKHGAGVVRMLTVQYRMHQAIM 448 Query: 456 EFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWER 515 + S+ Y G+ + SV G L+DL ++ +L IDT+ E Sbjct: 449 CWASEAMYHGQFTSHPSVAGHLLKDLPGVTDTEETRVPLL-------LIDTAGC-GLLEL 500 Query: 516 QRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDL----ISMKVPEDVE 571 + S+S+ NP E +V + L+ GV+ I VI PY+ Q DL +S K PE +E Sbjct: 501 EEEDSQSKGNPGEVRLVTLHIQALVDAGVQAGDIAVIAPYNLQVDLLRQSLSNKHPE-LE 559 Query: 572 VKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSH 631 +K+VDG+QGREKE ++L+ VRSN+ GE+GFL + RR+NV++TRA+R + V+ DS T+++H Sbjct: 560 IKSVDGFQGREKEAVLLTFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSHTVNNH 619 Query: 632 ETYKKMIEFFKEKG 645 + ++++F E G Sbjct: 620 AFLETLVDYFTEHG 633 >pir||T41580 probable dna-binding protein - fission yeast (Schizosaccharomyces pombe) >gi|2370467|emb|CAB11611.1| (Z98951) hypothetical protein [Schizosaccharomyces pombe] >gi|4239673|emb|CAA20863.1| (AL031546) putative dna-binding protein [Schizosaccharomyces pombe] Length = 660 Score = 262 bits (662), Expect = 1e-68 Identities = 208/687 (30%), Positives = 341/687 (49%), Gaps = 88/687 (12%) Query: 3 ITSFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEELGYFLV- 61 I F +R E V+ +++E++ ++R +R G A++NL ++ G + Sbjct: 15 IQKFGDREIEFVDEAQKSEVDETEKSIKRFPLSVLQRKGLALINLRIGVVKTGFGGKTII 74 Query: 62 ------KYGRNREIKTE-ISVGDLVVI-------SKRDPLKSDLL--GTVVEKGKRFIVV 105 + E+ S GD+V I K+ P ++D+ G V +R I V Sbjct: 75 DFEKDPAFSNGEELPANSFSPGDVVSIRQDFQSSKKKRPNETDISVEGVVTRVHERHISV 134 Query: 106 AL---ETVPEWALRDVRIDLYANDITFRRWLENLNTIKKA--GKRALRFY---------L 151 AL E +P R + L N +T+ R + K++ R FY + Sbjct: 135 ALKSEEDIPSSVTRLSVVKL-VNRVTYERMRHTMLEFKRSIPEYRNSLFYTLIGRKKADV 193 Query: 152 GLDEPSQGEEVNFVPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEV 211 +D+ G+ F+K LN SQ+KA+ ++ ++ L+HGP GTGKT TLVE+I+Q V Sbjct: 194 SIDQKLIGD---IKYFNKELNASQKKAVKFSIAVKELSLIHGPPGTGKTHTLVEIIQQLV 250 Query: 212 KRGNKVLATAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGE 271 R ++L SN+AVDN+V+RLS SGI +VR+GHP+R+ + + +L L Sbjct: 251 LRNKRILVCGASNLAVDNIVDRLSSSGIPMVRLGHPARLLPSILDHSLDVL--------- 301 Query: 272 LRELRVIGQSLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIK 331 + T RG+S++ + L++ + G R + Sbjct: 302 ----------------SRTGDNGDVIRGISEDIDVCLSKITKTKNGRERR---------E 336 Query: 332 LNRQVQKAFDDARKLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTI 391 + + +++ D RK E + +I+ + VV T A + +D IIDEA+Q+ Sbjct: 337 IYKNIRELRKDYRKYEAKTVANIVSASKVVFCTLHGAGSRQLKGQRFDAVIIDEASQALE 396 Query: 392 PSILIPLNKVERFVLAGDHKQLPPTILSLEAQELSRTLFEGLIE-RYPWKSEMLVVQYRM 450 P IPL + + +LAGDH QL P + +++ ++FE L++ + L +QYRM Sbjct: 397 PQCWIPLLGMNKVILAGDHMQLSPNV---QSKRPYISMFERLVKSQGDLVKCFLNIQYRM 453 Query: 451 NERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDT---- 506 +E I +FPS FY K++ E V+ L DL + + ++ I F DT Sbjct: 454 HELISKFPSDTFYDSKLVPAEEVKKRLLMDLENVEETELT-------DSPIYFYDTLGNY 506 Query: 507 SKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKV 566 + + + Q +S+ N EA+IV+ + LL G++ + I V+TPY+ Q LI + Sbjct: 507 QEDDRSEDMQNFYQDSKSNHWEAQIVSYHISGLLEAGLEAKDIAVVTPYNAQVALIRQLL 566 Query: 567 PE---DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVG 623 E +VE+ +VD QGREKE II SLVRSN + E+GFL + RRLNV++TR KR L V+G Sbjct: 567 KEKGIEVEMGSVDKVQGREKEAIIFSLVRSNDVREVGFLAEKRRLNVAITRPKRHLCVIG 626 Query: 624 DSSTLS-SHETYKKMIEFFKEKGCFIE 649 DS+T+ + E + + ++F +E ++ Sbjct: 627 DSNTVKWASEFFHQWVDFLEENAIVMD 653 >gi|6322835 DNA helicase A; Hcs1p [Saccharomyces cerevisiae] >gi|465704|sp|P34243|YKB7_YEAST HYPOTHETICAL 78.3 KD PROTEIN IN RAM2-ATP7 INTERGENIC REGION >gi|422147|pir||S34700 probable purine nucleotide-binding protein YKL017c - yeast (Saccharomyces cerevisiae) >gi|395256|emb|CAA52266.1| (X74152) orf4; homologous to human putative GTP-binding protein [Saccharomyces cerevisiae] >gi|486007|emb|CAA81852.1| (Z28017) ORF YKL017c [Saccharomyces cerevisiae] Length = 683 Score = 230 bits (581), Expect = 3e-59 Identities = 216/708 (30%), Positives = 349/708 (48%), Gaps = 113/708 (15%) Query: 14 VEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEEL-GYFLVKYGRNREI--- 69 ++ ERE +I+ + LS + + G AI N++ + I L G ++ G N + Sbjct: 13 IKHEREQDIQTTSRLLTTLSIQQLVQNGLAINNIHLENIRSGLIGKLYMELGPNLAVNDK 72 Query: 70 --KTEISVGDLVVI--------SKRDPL-----------KSDLLGTVVEKGKRFIVVALE 108 + +I VGD+V++ +K P +++ G V + I +ALE Sbjct: 73 IQRGDIKVGDIVLVRPAKTKVNTKTKPKVKKVSEDSNGEQAECSGVVYKMSDTQITIALE 132 Query: 109 TVPE------WALRDVRIDLYANDITFRRW---LENLNTIKKAGKRALRFYLGLDEP--- 156 + ++ + I N +T+ R + L+ I + + YL + P Sbjct: 133 ESQDVIATTFYSYSKLYILKTTNVVTYNRMESTMRKLSEISSPIQDKIIQYLVNERPFIP 192 Query: 157 SQGEEVNFVPF-DKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRG- 214 + N F + +LN SQ+ AI+ A+ + D ++HGP GTGKT TL+ELI+Q + + Sbjct: 193 NTNSFQNIKSFLNPNLNDSQKTAINFAINN-DLTIIHGPPGTGKTFTLIELIQQLLIKNP 251 Query: 215 -NKVLATAESNVAVDNLVERLSR--SGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGE 271 ++L SN++VD ++ERL+ ++RIGHP+R+ +L L Sbjct: 252 EERILICGPSNISVDTILERLTPLVPNNLLLRIGHPARLLDSNKRHSLDIL--------- 302 Query: 272 LRELRVIGQSLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIK 331 K++T K +EI KL + + + R E IK Sbjct: 303 ------------SKKNTIVKDI--------SQEIDKLIQENKKLKNYKQR--KENWNEIK 340 Query: 332 LNRQVQKAFDDARKLEERIARDIIREADVVLTT-NSSAALEVV-------DYDTYDVAII 383 L R+ D +K E + +D+I ++ +V+TT + S++ E+ ++ +D II Sbjct: 341 LLRK------DLKKREFKTIKDLIIQSRIVVTTLHGSSSRELCSLYRDDPNFQLFDTLII 394 Query: 384 DEATQSTIPSILIPL----NKVERFVLAGDHKQLPPTILSLEAQE----LSRTLFEGLIE 435 DE +Q+ P IPL N+ + VLAGD+KQLPPTI + + + L TLF+ +I+ Sbjct: 395 DEVSQAMEPQCWIPLIAHQNQFHKLVLAGDNKQLPPTIKTEDDKNVIHNLETTLFDRIIK 454 Query: 436 RYPWKS--EMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQ---SPNDS 490 +P + + L VQYRMN++IMEFPS Y GK++AD +V L DL S +D Sbjct: 455 IFPKRDMVKFLNVQYRMNQKIMEFPSHSMYNGKLLADATVANRLLIDLPTVDATPSEDDD 514 Query: 491 WGKILNPENVIVFIDTSKAE-NKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWI 549 KI +++ DT E + + S+ N E IV + ++ L S V I Sbjct: 515 DTKI-----PLIWYDTQGDEFQETADEATILGSKYNEGEIAIVKEHIENLRSFNVPENSI 569 Query: 550 GVITPYDDQRDLISMKVPE-----DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKD 604 GVI+PY+ Q + + + D+E+ TVDG+QGREK+VIILSLVRSN+ E+GFLK+ Sbjct: 570 GVISPYNAQVSHLKKLIHDELKLTDIEISTVDGFQGREKDVIILSLVRSNEKFEVGFLKE 629 Query: 605 LRRLNVSLTRAKRKLIVVGDSSTLS-SHETYKKMIEFFKEKGCFIEFP 651 RRLNV++TR +R+L+VVG+ L Y K + E+ + +P Sbjct: 630 ERRLNVAMTRPRRQLVVVGNIEVLQRCGNKYLKSWSEWCEENADVRYP 677 >dbj|BAB09253.1| (AB026643) DNA helicase-like [Arabidopsis thaliana] Length = 750 Score = 219 bits (553), Expect = 6e-56 Identities = 213/703 (30%), Positives = 332/703 (46%), Gaps = 113/703 (16%) Query: 3 ITSFINRLKELVEIEREAEIEAMRLEMRRLS------------------GIERERLGRAI 44 I F +++ +L+++ER+ E+E + E+ + G + L I Sbjct: 53 IDEFTSQMSQLLQVERDTELEVTQEELDVVPTPDESSDSSKPIEFLVRHGDAPQELCDTI 112 Query: 45 LNLNGKIIGEELG---YFLVKYGRNREIK-TEISVGDLVVISKRDPLKSDLL----GTVV 96 NL LG L K G N + T +S GD+V I D + G V Sbjct: 113 CNLYAVSTSTGLGGMHLVLFKVGGNHRLPPTTLSPGDMVCIRVCDSRGAGATACTQGFVH 172 Query: 97 EKGKR--FIVVALE------TVPEWALRDVRIDLY---ANDITFRRWLENLNTIKKAGKR 145 G+ I VALE T + + VRID A+ +T+ R E L ++K G + Sbjct: 173 NLGEDGCSIGVALESRHGDPTFSKLFGKSVRIDRIHGLADALTYERNCEALMLLQKNGLQ 232 Query: 146 ALRFYLGLDEP--SQGEEVNFV----------------PFDKSLNRSQRKAISKALGSE- 186 + + GE++ ++ P K + SQR+AI+ + + Sbjct: 233 KKNPSISVVATLFGDGEDITWLEQNDYVDWSEAELSDEPVSKLFDSSQRRAIALGVNKKR 292 Query: 187 DFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLSRSGIKIVRIGH 246 +V GP GTGKT L E+I V++G +VL TA +N AVDN+VE+L G+ IVR+G+ Sbjct: 293 PVMIVQGPPGTGKTGMLKEVITLAVQQGERVLVTAPTNAAVDNMVEKLLHLGLNIVRVGN 352 Query: 247 PSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGLSDEEII 306 P+R+S + +L ++ +L L K+ K R+ L D+ + Sbjct: 353 PARISSAVASKSLGEIVNS--------KLASFRAELERKKSDLRK---DLRQCLRDDVL- 400 Query: 307 KLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREADVVLTTNS 366 A G+ +L+ ++ + +K K E+ ++I+ A VV TN Sbjct: 401 --------AAGI-RQLLKQLGKTLK-------------KKEKETVKEILSNAQVVFATNI 438 Query: 367 SAALEVV-DYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSLEAQE- 424 AA ++ +T+D+ +IDEA QS PS IP+ + +R +L+GD QL P +LS +A E Sbjct: 439 GAADPLIRRLETFDLVVIDEAGQSIEPSCWIPILQGKRCILSGDPCQLAPVVLSRKALEG 498 Query: 425 -LSRTLFEGLIERYPW-KSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLV 482 L +L E + + L QYRMN+ I + SKE YGG + +S + L+ Sbjct: 499 GLGVSLLERAASLHDGVLATKLTTQYRMNDVIAGWASKEMYGGWL---KSAPSVASHLLI 555 Query: 483 EYQSPNDSWGKILNPENVIVFIDT-----SKAENKWER-QRRGSESRENPLEAEIVAKIV 536 + +W + +V +DT S + ER G+ S N EA+IV V Sbjct: 556 DSPFVKATW----ITQCPLVLLDTRMPYGSLSVGCEERLDPAGTGSLYNEGEADIVVNHV 611 Query: 537 DKLLSIGVKPEWIGVITPYDDQRDLI-----SMKVPEDVEVKTVDGYQGREKEVIILSLV 591 L+ GV P I V +PY Q L+ V + VEV T+D +QGRE + +I+S+V Sbjct: 612 ISLIYAGVSPMAIAVQSPYVAQVQLLRERLDDFPVADGVEVATIDSFQGREADAVIISMV 671 Query: 592 RSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETY 634 RSN LG +GFL D RR+NV++TRA++ + VV DSST+ H T+ Sbjct: 672 RSNNLGAVGFLGDSRRMNVAITRARKHVAVVCDSSTI-CHNTF 713 >pir||D72258 helicase-related protein - Thermotoga maritima (strain MSB8) >gi|4981975|gb|AAD36482.1|AE001793_12 (AE001793) helicase-related protein [Thermotoga maritima] Length = 245 Score = 215 bits (543), Expect = 9e-55 Identities = 104/157 (66%), Positives = 131/157 (83%) Query: 494 ILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVIT 553 +L+P+NV+VFIDT +++ERQR+ S SRENPLEA+IV ++V+KLLS+GVK +WIG+IT Sbjct: 89 VLSPKNVLVFIDTKNRSDRFERQRKDSPSRENPLEAQIVKEVVEKLLSMGVKEDWIGIIT 148 Query: 554 PYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLT 613 PYDDQ +LI + VEV +VDG+QGREKEVII+S VRSNK GEIGFL+DLRRLNVSLT Sbjct: 149 PYDDQVNLIRELIEAKVEVHSVDGFQGREKEVIIISFVRSNKNGEIGFLEDLRRLNVSLT 208 Query: 614 RAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGCFIEF 650 RAKRKLI GDSSTLS H TY++ +EF K+KG ++ F Sbjct: 209 RAKRKLIATGDSSTLSVHPTYRRFVEFVKKKGTYVIF 245 >emb|CAC18314.1| (AL451022) probable HUPF1 protein [Neurospora crassa] Length = 1093 Score = 215 bits (541), Expect = 2e-54 Identities = 177/507 (34%), Positives = 252/507 (48%), Gaps = 85/507 (16%) Query: 165 VPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGN-KVLATAES 223 VP LN SQ AI + L S L+ GP GTGKT T +I K N +VL A S Sbjct: 450 VPGLPELNASQIAAIKQVL-SNPLSLIQGPPGTGKTVTSATIIYHLAKMSNSQVLVCAPS 508 Query: 224 NVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLA 283 NVAVD L ER+ R+G+K+VR+ SR E+++++L ++ Sbjct: 509 NVAVDQLCERIHRTGLKVVRLTAKSREDV---ESSVSFLALHEQV--------------- 550 Query: 284 EKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDA 343 R +++E+ L + K E +L+ Q +K F Sbjct: 551 -------------RMNTTNKELDGLVKLK--------------TETGELSSQDEKRF--- 580 Query: 344 RKLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNK-VE 402 ++L + R+I++ ADVV T A + + +IDE+TQS P +IPL + Sbjct: 581 KQLTRQAEREILQNADVVCCTCVGAGDPRLSKMKFRNVLIDESTQSAEPECMIPLVLGCK 640 Query: 403 RFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSK 460 + VL GDHKQL P I++ +A + L+++LFE L+ + + L VQYRM+ + EFPS Sbjct: 641 QVVLVGDHKQLGPVIMNKKAAKAGLNQSLFERLV-KLQFTPIRLKVQYRMHPCLSEFPSN 699 Query: 461 EFYGGKIIADESVRGIT----LRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQ 516 FY G + G+T LR V++ P PE ++F S N E Sbjct: 700 MFYEGSL-----QNGVTAAERLRKDVDFPWPV--------PETPMMF--WSNLGN--EEI 742 Query: 517 RRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE-------- 568 S N EA V KIV + GVKP IGVITPY+ QR I + Sbjct: 743 SASGTSYLNRTEAANVEKIVTRFFKAGVKPADIGVITPYEGQRSYIVNTMQNTGTFKKES 802 Query: 569 --DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSS 626 +VEV +VD +QGREK+ I+LS VRSN+ IGFL D RRLNV+LTRAK L+++G+ Sbjct: 803 YREVEVASVDAFQGREKDFIVLSCVRSNENQGIGFLSDPRRLNVALTRAKYGLVIIGNPK 862 Query: 627 TLSSHETYKKMIEFFKEKGCFIEFPFS 653 L HE + ++ FK+K C +E P + Sbjct: 863 VLCKHELWHHLLVHFKDKKCLVEGPLT 889 >pir||T43280 nonsense-mediated mRNA decay trans-acting factor - Caenorhabditis elegans >gi|3328177|gb|AAC26789.1| (AF074017) nonsense-mediated mRNA decay trans-acting factor [Caenorhabditis elegans] Length = 1069 Score = 206 bits (519), Expect = 6e-52 Identities = 183/561 (32%), Positives = 273/561 (48%), Gaps = 95/561 (16%) Query: 120 IDLYANDITFRRWLENLNTIKKAGKRALRFYLGLDEPSQGEEVNFVPFD----------K 169 +D+ N TF R + L + K A+ YL E + FD Sbjct: 386 VDVVWNATTFERQYKALAALLNDSK-AISPYLYQKLLGHPAEEMMLKFDLPRRLSVAGLP 444 Query: 170 SLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKR--GNKVLATAESNVAV 227 LN SQ +A+ + L + L+ GP GTGKT ++ V++ GN VL + SN+AV Sbjct: 445 ELNSSQMQAVKQVL-TRPLSLIQGPPGTGKTVVSATIVYHLVQKTEGN-VLVCSPSNIAV 502 Query: 228 DNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRD 287 D+L E++ ++G+K+VR+ SR ETT+ YL QH+L +V+G + Sbjct: 503 DHLAEKIHKTGLKVVRLCARSREHS---ETTVPYLTLQHQL-------KVMGGA------ 546 Query: 288 TYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLE 347 E+ KL + K A L + DD R ++ Sbjct: 547 ----------------ELQKLIQLKDEAGELEFK-------------------DDLRYMQ 571 Query: 348 ERIARD--IIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNK-VERF 404 + ++ ++ ADV+ T SSAA + +IDE+TQ+T P IL+ + + V + Sbjct: 572 LKRVKEHELLAAADVICCTCSSAADARLSKIRTRTVLIDESTQATEPEILVSIMRGVRQL 631 Query: 405 VLAGDHKQLPPTILSLEAQ--ELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEF 462 VL GDH QL P ++ +A LS++LFE L+ + L VQYRM+ + EFPS F Sbjct: 632 VLVGDHCQLGPVVICKKAAIAGLSQSLFERLV-LLGIRPFRLQVQYRMHPVLSEFPSNVF 690 Query: 463 YGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSES 522 Y G + G+T D + W K P F S +E E G+ S Sbjct: 691 YDGSL-----QNGVTENDR-HMTGVDWHWPK---PNKPAFFWHCSGSE---ELSASGT-S 737 Query: 523 RENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLI----------SMKVPEDVEV 572 N EA V K+V KL+ GV+P IGVIT Y+ QR I + K+ E+VE+ Sbjct: 738 FLNRTEAANVEKLVSKLIKAGVQPHQIGVITSYEGQRSFIVNYMHTQGTLNSKLYENVEI 797 Query: 573 KTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHE 632 +VD +QGREK+ II++ VRSN + IGFL D RRLNV++TRAK L++VG++ L+ H+ Sbjct: 798 ASVDAFQGREKDYIIVTCVRSNDILGIGFLSDPRRLNVAITRAKYGLVLVGNAKVLARHD 857 Query: 633 TYKKMIEFFKEKGCFIEFPFS 653 + ++I +K K E P + Sbjct: 858 LWHELINHYKSKEMLYEGPIN 878 >gi|6323726 putative helicase; Nam7p [Saccharomyces cerevisiae] >gi|400350|sp|P30771|NAM7_YEAST NAM7 PROTEIN (NONSENSE-MEDIATED MRNA DECAY PROTEIN 1) (UP-FRAMESHIFT SUPPRESSOR 1) >gi|83347|pir||S23408 prematurely terminated mRNA decay factor NAM7 - yeast (Saccharomyces cerevisiae) >gi|4023|emb|CAA44266.1| (X62394) helicase [Saccharomyces cerevisiae] >gi|173142|gb|AAA35197.1| (M76659) zinc finger protein [Saccharomyces cerevisiae] >gi|807962|emb|CAA89226.1| (Z49259) Nam7p [Saccharomyces cerevisiae] Length = 971 Score = 202 bits (508), Expect = 1e-50 Identities = 167/501 (33%), Positives = 242/501 (47%), Gaps = 83/501 (16%) Query: 165 VPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVK-RGNKVLATAES 223 +P LN SQ A+S L L+ GP GTGKT T ++ K +++L A S Sbjct: 403 IPNFAQLNSSQSNAVSHVL-QRPLSLIQGPPGTGKTVTSATIVYHLSKIHKDRILVCAPS 461 Query: 224 NVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLA 283 NVAVD+L +L G+K+VR+ SR + LA H L G Sbjct: 462 NVAVDHLAAKLRDLGLKVVRLTAKSREDVESSVSNLAL----HNLVG------------- 504 Query: 284 EKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDA 343 RGA+G L+ E +L+ K F Sbjct: 505 -----------------------------RGAKGELKNLLKLKDEVGELSASDTKRFV-- 533 Query: 344 RKLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNK-VE 402 KL + +I+ +ADVV T A + +D + +IDE+TQ++ P LIP+ K + Sbjct: 534 -KLVRKTEAEILNKADVVCCTCVGAGDKRLD-TKFRTVLIDESTQASEPECLIPIVKGAK 591 Query: 403 RFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIE--RYPWKSEMLVVQYRMNERIMEFP 458 + +L GDH+QL P IL +A + L ++LFE LI P + E VQYRMN + EFP Sbjct: 592 QVILVGDHQQLGPVILERKAADAGLKQSLFERLISLGHVPIRLE---VQYRMNPYLSEFP 648 Query: 459 SKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRR 518 S FY G + G+T+ + PN + + ++ + + + E Sbjct: 649 SNMFYEGSL-----QNGVTIE---QRTVPNSKFPWPIRGIPMMFWANYGREEIS-----A 695 Query: 519 GSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPED--------- 569 S N +EA +I+ KL GVKPE IGVITPY+ QR I + + Sbjct: 696 NGTSFLNRIEAMNCERIITKLFRDGVKPEQIGVITPYEGQRAYILQYMQMNGSLDKDLYI 755 Query: 570 -VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL 628 VEV +VD +QGREK+ IILS VR+N+ IGFL+D RRLNV LTRAK L+++G+ +L Sbjct: 756 KVEVASVDAFQGREKDYIILSCVRANEQQAIGFLRDPRRLNVGLTRAKYGLVILGNPRSL 815 Query: 629 SSHETYKKMIEFFKEKGCFIE 649 + + + ++ F+EKGC +E Sbjct: 816 ARNTLWNHLLIHFREKGCLVE 836 >dbj|BAB10240.1| (AB013394) prematurely terminated mRNA decay factor-like protein [Arabidopsis thaliana] Length = 1235 Score = 200 bits (504), Expect = 3e-50 Identities = 167/505 (33%), Positives = 245/505 (48%), Gaps = 79/505 (15%) Query: 165 VPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGN-KVLATAES 223 VP LN SQ A+ L + L+ GP GTGKT T ++ K+G +VL A S Sbjct: 480 VPGLPELNASQVNAVKSVL-QKPISLIQGPPGTGKTVTSAAIVYHMAKQGQGQVLVCAPS 538 Query: 224 NVAVDNLVERLSRSGIKIVRIGHPSR--VSKHLHETTLAYLITQHELYGELRELRVIGQS 281 NVAVD L E++S +G+K+VR+ SR VS + TL Y + +H E EL + Q Sbjct: 539 NVAVDQLAEKISATGLKVVRLCAKSREAVSSPVEYLTLHYQV-RHLDTSEKSELHKLQQ- 596 Query: 282 LAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFD 341 L DE+ +L+ +K + Sbjct: 597 ------------------LKDEQG-------------------------ELSSSDEKKYK 613 Query: 342 DARKLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNK- 400 + ++ ER +I + ADV+ T AA + + +IDE+TQ+T P LIPL Sbjct: 614 NLKRATER---EITQSADVICCTCVGAADLRLSNFRFRQVLIDESTQATEPECLIPLVLG 670 Query: 401 VERFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFP 458 V++ VL GDH QL P I+ +A L+++LFE L+ K L VQYRM+ + EFP Sbjct: 671 VKQVVLVGDHCQLGPVIMCKKAARAGLAQSLFERLVT-LGIKPIRLQVQYRMHPALSEFP 729 Query: 459 SKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRR 518 S FY G + G+T+ +E Q+ + + + ++ + E Sbjct: 730 SNSFYEGTL-----QNGVTI---IERQTTGIDFPWPVPNRPMFFYVQLGQEEIS-----A 776 Query: 519 GSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLI----------SMKVPE 568 S N EA V K+V L GV P IGVITPY+ QR I ++ + Sbjct: 777 SGTSYLNRTEAANVEKLVTAFLKSGVVPSQIGVITPYEGQRAYIVNYMARNGSLRQQLYK 836 Query: 569 DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL 628 ++EV +VD +QGREK+ IILS VRSN+ IGFL D RRLNV+LTRA+ ++++G+ L Sbjct: 837 EIEVASVDSFQGREKDYIILSCVRSNEHQGIGFLNDPRRLNVALTRARYGIVILGNPKVL 896 Query: 629 SSHETYKKMIEFFKEKGCFIEFPFS 653 S + ++ +KE C +E P + Sbjct: 897 SKQPLWNGLLTHYKEHECLVEGPLN 921 >pir||T40065 tRNA-splicing endonuclease positive effector - fission yeast (Schizosaccharomyces pombe) >gi|4007798|emb|CAA22438.1| (AL034463) tRNA-splicing endonuclease positive effector [Schizosaccharomyces pombe] Length = 1944 Score = 197 bits (496), Expect = 3e-49 Identities = 158/530 (29%), Positives = 258/530 (47%), Gaps = 80/530 (15%) Query: 171 LNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRG---------------- 214 +N Q AI + ++ F L+ GP GTGKT+T++ +I + Sbjct: 1271 VNEPQAYAIYASSVNDGFTLIQGPPGTGKTKTILGMIGAVLTSSSQGLQFNVPGQTRKTS 1330 Query: 215 -NKVLATAESNVAVDNLVERLS-----RSGIK----IVRIGHPSRVSKHLHETTLA-YLI 263 NK+L A SN A+D ++ R+ GIK ++R+G +S H E TL +I Sbjct: 1331 KNKILICAPSNAAIDEILLRIKAGVYDHEGIKFFPKVIRVGFGDSISVHAKEFTLEEQMI 1390 Query: 264 TQHELYGELRELRVIGQSLAEKR-DTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARL 322 Q EL ++ S K+ D+ K R L E+ R S+ L Sbjct: 1391 KQMELTNLKKDQEANNSSDTRKKYDSIIKKRDSLREDL---------EKFRSTGKNSSIL 1441 Query: 323 IMEMAEWIKLNRQVQKAFDDARK-----------LEERIARDIIREADVVLTTNSSAALE 371 ++ E K ++++ DD R+ L+++I +++EAD+V T S++ E Sbjct: 1442 EAQLREITKQKNMLEQSLDDMRERQRSTNRNLDVLKKQIQNQLLQEADIVCATLSASGHE 1501 Query: 372 VVDYD--TYDVAIIDEATQSTIPSILIPLNK-VERFVLAGDHKQLPPTILSLEAQEL--S 426 ++ T+ IIDEA Q+ S +IPL E V+ GD QLPPT+LS + + S Sbjct: 1502 LLLNAGLTFRTVIIDEAAQAVELSSIIPLKYGCESCVMVGDPNQLPPTVLSKTSAKFGYS 1561 Query: 427 RTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQS 486 ++L+ + +++ + +L +QYRMN I FPSK FY K++ ++ +T R ++ Sbjct: 1562 QSLYVRMFKQHNESACLLSIQYRMNPEISRFPSKFFYNSKLLDGPNMSAVTSRPW--HED 1619 Query: 487 PNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKP 546 P + N F + S+S N EA + + ++L+ + Sbjct: 1620 PQLGIYRFFNVHGTEAFSN--------------SKSLYNVEEASFILLLYERLIQCYLNI 1665 Query: 547 EW---IGVITPYDDQRDLISMK--------VPEDVEVKTVDGYQGREKEVIILSLVRSNK 595 ++ IGV+TPY Q + + + + +++ TVDG+QG+EK++II S VRS+ Sbjct: 1666 DFEGKIGVVTPYRSQVQQLRSQFQRKYGSIIFKHLDIHTVDGFQGQEKDIIIFSCVRSSM 1725 Query: 596 LGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKG 645 G IGFL+DLRRLNV+LTRAK L +VG+S L + + +IE K +G Sbjct: 1726 SGGIGFLQDLRRLNVALTRAKSSLYIVGNSKPLMQEDIFYSLIEDAKTRG 1775 >gb|AAB94785.1| (AC003972) pNORF1 [Homo sapiens] >gi|3328175|gb|AAC26788.1| (AF074016) nonsense-mediated mRNA decay trans-acting factor [Homo sapiens] Length = 1118 Score = 192 bits (484), Expect = 7e-48 Identities = 159/497 (31%), Positives = 246/497 (48%), Gaps = 77/497 (15%) Query: 171 LNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGN-KVLATAESNVAVDN 229 LN SQ A+ L L+ GP GTGKT T ++ ++GN VL A SN+AVD Sbjct: 471 LNHSQVYAVKTVL-QRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQ 529 Query: 230 LVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTY 289 L E++ ++G+K+VR+ SR + + LA L+ ++R + Sbjct: 530 LTEKIHQTGLKVVRLCAKSREAIDSPVSFLA-------LHNQIRNMD------------- 569 Query: 290 TKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEER 349 S E+ KL + K E +L+ +K + R L+ Sbjct: 570 -----------SMPELQKLQQLKD--------------ETGELSSADEKRY---RALKRT 601 Query: 350 IARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNK-VERFVLAG 408 R+++ ADV+ T A + + +IDE+TQ+T P ++P+ ++ +L G Sbjct: 602 AERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVG 661 Query: 409 DHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGK 466 DH QL P ++ +A + LS++LFE L+ + L VQYRM+ + FPS FY G Sbjct: 662 DHCQLGPVVMCKKAAKAGLSQSLFERLVV-LGIRPIRLQVQYRMHPALSAFPSNIFYEGS 720 Query: 467 IIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENP 526 + G+T D V+ + + W + P+ + F T E E G+ S N Sbjct: 721 L-----QNGVTAADRVK-KGFDFQWPQ---PDKPMFFYVTQGQE---EIASSGT-SYLNR 767 Query: 527 LEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISM----------KVPEDVEVKTVD 576 EA V KI KLL G KP+ IG+ITPY+ QR + K+ ++VE+ +VD Sbjct: 768 TEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVD 827 Query: 577 GYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKK 636 +QGREK+ IILS VR+N+ IGFL D RRLNV+LTRA+ +I+VG+ LS + Sbjct: 828 AFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNH 887 Query: 637 MIEFFKEKGCFIEFPFS 653 ++ ++KE+ +E P + Sbjct: 888 LLNYYKEQKVLVEGPLN 904 >gb|AAC51140.1| (U59323) type 1 RNA helicase pNORF1 [Homo sapiens] Length = 1118 Score = 192 bits (484), Expect = 7e-48 Identities = 159/497 (31%), Positives = 246/497 (48%), Gaps = 77/497 (15%) Query: 171 LNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGN-KVLATAESNVAVDN 229 LN SQ A+ L L+ GP GTGKT T ++ ++GN VL A SN+AVD Sbjct: 471 LNHSQVYAVKTVL-QRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQ 529 Query: 230 LVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTY 289 L E++ ++G+K+VR+ SR + + LA L+ ++R + Sbjct: 530 LTEKIHQTGLKVVRLCAKSREAIDSPVSFLA-------LHNQIRNMD------------- 569 Query: 290 TKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEER 349 S E+ KL + K E +L+ +K + R L+ Sbjct: 570 -----------SMPELQKLQQLKD--------------ETGELSSADEKRY---RALKRT 601 Query: 350 IARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNK-VERFVLAG 408 R+++ ADV+ T A + + +IDE+TQ+T P ++P+ ++ +L G Sbjct: 602 AERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVG 661 Query: 409 DHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGK 466 DH QL P ++ +A + LS++LFE L+ + L VQYRM+ + FPS FY G Sbjct: 662 DHCQLGPVVMCKKAAKAGLSQSLFERLVV-LGIRPIRLQVQYRMHPALSAFPSNIFYEGS 720 Query: 467 IIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENP 526 + G+T D V+ + + W + P+ + F T E E G+ S N Sbjct: 721 L-----QNGVTAADRVK-KGFDFQWPQ---PDKPMFFYVTQGQE---EIASSGT-SYLNR 767 Query: 527 LEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISM----------KVPEDVEVKTVD 576 EA V KI KLL G KP+ IG+ITPY+ QR + K+ ++VE+ +VD Sbjct: 768 TEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVD 827 Query: 577 GYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKK 636 +QGREK+ IILS VR+N+ IGFL D RRLNV+LTRA+ +I+VG+ LS + Sbjct: 828 AFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNH 887 Query: 637 MIEFFKEKGCFIEFPFS 653 ++ ++KE+ +E P + Sbjct: 888 LLNYYKEQKVLVEGPLN 904 >dbj|BAA19664.1| (D86988) KIAA0221 [Homo sapiens] Length = 1129 Score = 192 bits (484), Expect = 7e-48 Identities = 159/497 (31%), Positives = 246/497 (48%), Gaps = 77/497 (15%) Query: 171 LNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGN-KVLATAESNVAVDN 229 LN SQ A+ L L+ GP GTGKT T ++ ++GN VL A SN+AVD Sbjct: 482 LNHSQVYAVKTVL-QRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQ 540 Query: 230 LVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTY 289 L E++ ++G+K+VR+ SR + + LA L+ ++R + Sbjct: 541 LTEKIHQTGLKVVRLCAKSREAIDSPVSFLA-------LHNQIRNMD------------- 580 Query: 290 TKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEER 349 S E+ KL + K E +L+ +K + R L+ Sbjct: 581 -----------SMPELQKLQQLKD--------------ETGELSSADEKRY---RALKRT 612 Query: 350 IARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNK-VERFVLAG 408 R+++ ADV+ T A + + +IDE+TQ+T P ++P+ ++ +L G Sbjct: 613 AERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVG 672 Query: 409 DHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGK 466 DH QL P ++ +A + LS++LFE L+ + L VQYRM+ + FPS FY G Sbjct: 673 DHCQLGPVVMCKKAAKAGLSQSLFERLVV-LGIRPIRLQVQYRMHPALSAFPSNIFYEGS 731 Query: 467 IIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENP 526 + G+T D V+ + + W + P+ + F T E E G+ S N Sbjct: 732 L-----QNGVTAADRVK-KGFDFQWPQ---PDKPMFFYVTQGQE---EIASSGT-SYLNR 778 Query: 527 LEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISM----------KVPEDVEVKTVD 576 EA V KI KLL G KP+ IG+ITPY+ QR + K+ ++VE+ +VD Sbjct: 779 TEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVD 838 Query: 577 GYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKK 636 +QGREK+ IILS VR+N+ IGFL D RRLNV+LTRA+ +I+VG+ LS + Sbjct: 839 AFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNH 898 Query: 637 MIEFFKEKGCFIEFPFS 653 ++ ++KE+ +E P + Sbjct: 899 LLNYYKEQKVLVEGPLN 915 >sp|Q09820|YAC6_SCHPO HYPOTHETICAL 105.6 KD PROTEIN C16C9.06C IN CHROMOSOME I >gi|2130283|pir||S62476 hypothetical protein SPAC16C9.06c - fission yeast (Schizosaccharomyces pombe) Length = 935 Score = 191 bits (480), Expect = 2e-47 Identities = 164/510 (32%), Positives = 251/510 (49%), Gaps = 93/510 (18%) Query: 165 VPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELI-------RQEVKRGNKV 217 VP LN SQ +A+ +A+ S+ L+ GP GTGKT T ++ ++ K + V Sbjct: 397 VPNLPKLNASQSEAV-RAVLSKPLSLIQGPPGTGKTVTSASVVYHLATMQSRKRKSHSPV 455 Query: 218 LATAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRV 277 L A SNVAVD L E++ R+G+++VR+ SR E+++++L Sbjct: 456 LVCAPSNVAVDQLAEKIHRTGLRVVRVAAKSREDI---ESSVSFL--------------- 497 Query: 278 IGQSLAEKRDTYTKPTPKFRRGL---SDEEIIKLAERKRGARGLSARLIMEMAEWIKLNR 334 SL E+ Y K P+ +R L S+ + + + K+ R+++ AE Sbjct: 498 ---SLHEQIKNY-KFNPELQRLLKLRSENNELSIQDEKK------LRILVAAAE------ 541 Query: 335 QVQKAFDDARKLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSI 394 ++++R A V+ T A + + +IDEATQ++ P Sbjct: 542 -----------------KELLRAAHVICCTCVGAGDRRISKYKFRSVLIDEATQASEPEC 584 Query: 395 LIPLNK-VERFVLAGDHKQLPPTILSLEAQ--ELSRTLFEGLI--ERYPWKSEMLVVQYR 449 +IPL ++ VL GDH+QL P +++ + LS++LFE LI P++ LVVQYR Sbjct: 585 MIPLVLGAKQVVLVGDHQQLGPVVMNKKVALASLSQSLFERLIILGNSPFR---LVVQYR 641 Query: 450 MNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKA 509 M+ + EFPS FY G + G+T + + + + W + P++ ++F A Sbjct: 642 MHPCLSEFPSNTFYEGTL-----QNGVTTSERIA-RHVDFPW---IQPDSPLMFY----A 688 Query: 510 ENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPED 569 E S N EA KIV L V PE IG++TPYD QR I + + Sbjct: 689 NFGQEELSASGTSFLNRTEASTCEKIVTTFLRSNVLPEQIGIVTPYDGQRSYIVQYMQNN 748 Query: 570 ----------VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKL 619 VEV +VD +QGREK+ IILS VRS++ IGF+ D RRLNV+LTRAK + Sbjct: 749 GSMQKDLYKAVEVASVDAFQGREKDFIILSCVRSSEHQGIGFVNDPRRLNVALTRAKYGV 808 Query: 620 IVVGDSSTLSSHETYKKMIEFFKEKGCFIE 649 IV+G+ L+ H + + KEKG +E Sbjct: 809 IVLGNPKVLAKHALWYHFVLHCKEKGYLVE 838 >pir||T37779 probable regulator of nonsense transcript stability - fission yeast (Schizosaccharomyces pombe) >gi|4894186|emb|CAA91194.2| (Z54366) putative regulator of nonsense transcript stability [Schizosaccharomyces pombe] Length = 925 Score = 191 bits (480), Expect = 2e-47 Identities = 164/510 (32%), Positives = 251/510 (49%), Gaps = 93/510 (18%) Query: 165 VPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELI-------RQEVKRGNKV 217 VP LN SQ +A+ +A+ S+ L+ GP GTGKT T ++ ++ K + V Sbjct: 387 VPNLPKLNASQSEAV-RAVLSKPLSLIQGPPGTGKTVTSASVVYHLATMQSRKRKSHSPV 445 Query: 218 LATAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRV 277 L A SNVAVD L E++ R+G+++VR+ SR E+++++L Sbjct: 446 LVCAPSNVAVDQLAEKIHRTGLRVVRVAAKSREDI---ESSVSFL--------------- 487 Query: 278 IGQSLAEKRDTYTKPTPKFRRGL---SDEEIIKLAERKRGARGLSARLIMEMAEWIKLNR 334 SL E+ Y K P+ +R L S+ + + + K+ R+++ AE Sbjct: 488 ---SLHEQIKNY-KFNPELQRLLKLRSENNELSIQDEKK------LRILVAAAE------ 531 Query: 335 QVQKAFDDARKLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSI 394 ++++R A V+ T A + + +IDEATQ++ P Sbjct: 532 -----------------KELLRAAHVICCTCVGAGDRRISKYKFRSVLIDEATQASEPEC 574 Query: 395 LIPLNK-VERFVLAGDHKQLPPTILSLEAQ--ELSRTLFEGLI--ERYPWKSEMLVVQYR 449 +IPL ++ VL GDH+QL P +++ + LS++LFE LI P++ LVVQYR Sbjct: 575 MIPLVLGAKQVVLVGDHQQLGPVVMNKKVALASLSQSLFERLIILGNSPFR---LVVQYR 631 Query: 450 MNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKA 509 M+ + EFPS FY G + G+T + + + + W + P++ ++F A Sbjct: 632 MHPCLSEFPSNTFYEGTL-----QNGVTTSERIA-RHVDFPW---IQPDSPLMFY----A 678 Query: 510 ENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPED 569 E S N EA KIV L V PE IG++TPYD QR I + + Sbjct: 679 NFGQEELSASGTSFLNRTEASTCEKIVTTFLRSNVLPEQIGIVTPYDGQRSYIVQYMQNN 738 Query: 570 ----------VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKL 619 VEV +VD +QGREK+ IILS VRS++ IGF+ D RRLNV+LTRAK + Sbjct: 739 GSMQKDLYKAVEVASVDAFQGREKDFIILSCVRSSEHQGIGFVNDPRRLNVALTRAKYGV 798 Query: 620 IVVGDSSTLSSHETYKKMIEFFKEKGCFIE 649 IV+G+ L+ H + + KEKG +E Sbjct: 799 IVLGNPKVLAKHALWYHFVLHCKEKGYLVE 828 >gi|11426635 regulator of nonsense transcripts 1 [Homo sapiens] Length = 1118 Score = 190 bits (478), Expect = 4e-47 Identities = 158/497 (31%), Positives = 246/497 (48%), Gaps = 77/497 (15%) Query: 171 LNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNK-VLATAESNVAVDN 229 LN SQ A+ L L+ GP GTGKT T ++ ++G + VL A SN+AVD Sbjct: 471 LNHSQVYAVKTVL-QRPLSLIQGPPGTGKTVTSATIVYHLARQGCRPVLVCAPSNIAVDQ 529 Query: 230 LVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTY 289 L E++ ++G+K+VR+ SR + + LA L+ ++R + Sbjct: 530 LTEKIHQTGLKVVRLCAKSREAIDSPVSFLA-------LHNQIRNMD------------- 569 Query: 290 TKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEER 349 S E+ KL + K E +L+ +K + R L+ Sbjct: 570 -----------SMPELQKLQQLKD--------------ETGELSSADEKRY---RALKRT 601 Query: 350 IARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNK-VERFVLAG 408 R+++ ADV+ T A + + +IDE+TQ+T P ++P+ ++ +L G Sbjct: 602 AERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVG 661 Query: 409 DHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGK 466 DH QL P ++ +A + LS++LFE L+ + L VQYRM+ + FPS FY G Sbjct: 662 DHCQLGPVVMCKKAAKAGLSQSLFERLVV-LGIRPIRLQVQYRMHPALSAFPSNIFYEGS 720 Query: 467 IIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENP 526 + G+T D V+ + + W + P+ + F T E E G+ S N Sbjct: 721 L-----QNGVTAADRVK-KGFDFQWPQ---PDKPMFFYVTQGQE---EIASSGT-SYLNR 767 Query: 527 LEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISM----------KVPEDVEVKTVD 576 EA V KI KLL G KP+ IG+ITPY+ QR + K+ ++VE+ +VD Sbjct: 768 TEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVD 827 Query: 577 GYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKK 636 +QGREK+ IILS VR+N+ IGFL D RRLNV+LTRA+ +I+VG+ LS + Sbjct: 828 AFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNH 887 Query: 637 MIEFFKEKGCFIEFPFS 653 ++ ++KE+ +E P + Sbjct: 888 LLNYYKEQKVLVEGPLN 904 >gi|4506479 regulator of nonsense transcripts 1 [Homo sapiens] >gi|1575536|gb|AAC50771.1| (U65533) regulator of nonsense transcript stability [Homo sapiens] Length = 1118 Score = 190 bits (477), Expect = 5e-47 Identities = 159/497 (31%), Positives = 245/497 (48%), Gaps = 77/497 (15%) Query: 171 LNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGN-KVLATAESNVAVDN 229 LN SQ A+ L L+ GP GTGKT T ++ ++ N VL A SN+AVD Sbjct: 471 LNHSQVYAVKTVL-QRPLSLIQGPPGTGKTVTSATIVYHLARQDNGPVLVCAPSNIAVDQ 529 Query: 230 LVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTY 289 L E++ ++G+K+VR+ SR + + LA L+ ++R + Sbjct: 530 LTEKIHQTGLKVVRLCPKSREAIDSPVSFLA-------LHNQIRNMD------------- 569 Query: 290 TKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEER 349 S E+ KL + K E +L+ +K + R L+ Sbjct: 570 -----------SMPELQKLQQLKD--------------ETGELSSADEKRY---RALKRT 601 Query: 350 IARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNK-VERFVLAG 408 R+++ ADV+ T A + + +IDE+TQ+T P ++P+ ++ +L G Sbjct: 602 AERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVG 661 Query: 409 DHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGK 466 DH QL P ++ +A + LS++LFE L+ + L VQYRM+ + FPS FY G Sbjct: 662 DHCQLGPVVMCKKAAKAGLSQSLFERLVV-LGIRPIRLQVQYRMHPALSAFPSNIFYEGS 720 Query: 467 IIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENP 526 + G+T D V+ + + W + P+ + F T E E G+ S N Sbjct: 721 L-----QNGVTAADRVK-KGFDFQWPQ---PDKPMFFYVTQGQE---EIASSGT-SYLNR 767 Query: 527 LEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISM----------KVPEDVEVKTVD 576 EA V KI KLL G KP+ IG+ITPY+ QR + K+ ++VE+ +VD Sbjct: 768 TEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVD 827 Query: 577 GYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKK 636 +QGREK+ IILS VR+N+ IGFL D RRLNV+LTRA+ +I+VG+ LS + Sbjct: 828 AFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNH 887 Query: 637 MIEFFKEKGCFIEFPFS 653 ++ F+KE+ +E P + Sbjct: 888 LLIFYKEQKVLVEGPLN 904 >sp|Q92355|YDHA_SCHPO HYPOTHETICAL 192.5 KD PROTEIN C6G9.10C IN CHROMOSOME I >gi|7490496|pir||T39072 DNA2-NAM7 helicase family protein - fission yeast (Schizosaccharomyces pombe) >gi|1644322|emb|CAB03612.1| (Z81317) DNA2-NAM7 helicase family protein [Schizosaccharomyces pombe] Length = 1687 Score = 184 bits (462), Expect = 3e-45 Identities = 169/606 (27%), Positives = 284/606 (45%), Gaps = 95/606 (15%) Query: 103 IVVALETVPEWALRDVRIDLYANDITFRRWLENLNTIKK--AGKRALRFYLGLDE----- 155 ++V L T+P + + L N + L NL T + AG R L ++ D+ Sbjct: 1052 VLVVLRTLPSMEILN---KLQGNCALWFLKLTNLATFTRQYAGIRGLPYFHLADDIIRAR 1108 Query: 156 ------PSQGEEVNFVPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRT------- 202 E+ +N Q KAI AL + F L+ GP GTGKT+T Sbjct: 1109 PCSQPVKHSSSEIKAAMKRYQVNEPQAKAIMCALDNNGFTLIQGPPGTGKTKTIIGIISA 1168 Query: 203 -LVELIRQEVKRGNK----------VLATAESNVAVDNLVERLSRSGI---------KIV 242 LV+L R + R N+ +L A SN AVD ++ RL R + ++V Sbjct: 1169 LLVDLSRYHITRPNQQSKSTESKQQILLCAPSNAAVDEVLLRLKRGFLLENGEKYIPRVV 1228 Query: 243 RIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIG--QSLAEKRDTYTKPTPKFRRGL 300 RIG+P ++ + + +L Y T+ +L + +G Q L RDT+ K Sbjct: 1229 RIGNPETINVSVRDLSLEYQ-TEKQLLEVNQGAIDLGSLQELTRWRDTFYDCIQKI---- 1283 Query: 301 SDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARK-----------LEER 349 EE+ K + R + L E+ I ++ ++ + L ++ Sbjct: 1284 --EELEKQIDVARDVAEDTKSLGKELQNKINEKNLAEQKVEELQSQSFTKNKEVDLLRKK 1341 Query: 350 IARDIIREADVVLTTNSSAALEVVDYDT--YDVAIIDEATQSTIPSILIPLNK-VERFVL 406 + I+++ADVV T S + ++V + + + IIDEA Q+ +IPL ++ +L Sbjct: 1342 AQKAILKQADVVCATLSGSGHDLVAHSSLNFSTVIIDEAAQAVELDTIIPLRYGAKKCIL 1401 Query: 407 AGDHKQLPPTILSLEAQEL--SRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYG 464 GD QLPPT+LS +A L S++LF + + + + +L +QYRM+ I FPSK+FY Sbjct: 1402 VGDPNQLPPTVLSKKAASLNYSQSLFVRIQKNFSNQMCLLSIQYRMHPDISHFPSKKFYD 1461 Query: 465 GKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRE 524 ++ +++ + W +NP+ F + + + + + S Sbjct: 1462 SRLEDGDNMA----------EKTQQVWH--VNPK----FTQYRLFDVRGKERTSNTMSTY 1505 Query: 525 NPLEAEIVAKIVDKLLSIGVKPEW---IGVITPYDDQ----RDLISMKVPED----VEVK 573 N E E + +VD+LL+ + IGVITPY Q R +K + ++++ Sbjct: 1506 NLEEVEYLVNMVDELLNKFPDVNFTGRIGVITPYRSQLHELRRAFKVKYGKSFMSTIDIQ 1565 Query: 574 TVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHET 633 TVDG+QG+EK++I S V+S IGFL+D RRLNV+LTRA+ L+++G+ TL + + Sbjct: 1566 TVDGFQGQEKDIIFFSCVKSYSKHGIGFLRDFRRLNVALTRARSSLLIIGNMETLKTDDL 1625 Query: 634 YKKMIE 639 + +++ Sbjct: 1626 WGSLVD 1631 >emb|CAC10094.1| (AL442164) related to SEN1 protein [Neurospora crassa] Length = 1825 Score = 174 bits (437), Expect = 2e-42 Identities = 178/666 (26%), Positives = 301/666 (44%), Gaps = 130/666 (19%) Query: 72 EISVGDLVVISK-RDPLK--------SDLLGTVVEKGKRFIVVALETVPEWALRDVRIDL 122 ++S GD+V+ISK ++PL+ S + T +K +V L L + L Sbjct: 1033 QLSEGDIVIISKGQNPLQEPEELHCLSRIWKTTYKKDNVEVVYRLNAKGNQILPAL---L 1089 Query: 123 YANDITFRRWLENLNTIKK--AGKRALRFYLGLDEPSQGEEVNFVPFDK----------S 170 ++ T + + N+ TI++ A +L++Y +DE + E + F + + Sbjct: 1090 PGSEFTVVK-ITNMTTIEREYAALESLQYYDLMDEVLRAEPSPMLSFGEENIKNTMKNWN 1148 Query: 171 LNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELI----------------------- 207 LN Q KAI A ++ F L+ GP GTGKT+T+V ++ Sbjct: 1149 LNPGQAKAILNAKENDGFTLIQGPPGTGKTKTIVAMVGCLLTGVLKNPTAGVAIGRPGLG 1208 Query: 208 -RQEVKRGNKVLATAESNVAVDNLVERLSRSGIK----------IVRIGHPSRVSKHLHE 256 + K+L A SN AVD LV RL ++G+K +VR+G ++ + + Sbjct: 1209 AAKNNAPAKKLLVCAPSNAAVDELVLRL-KNGVKTQNGTTHQIEVVRLGRSDAINSAVKD 1267 Query: 257 TTLAYLI---------------TQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGLS 301 TL L+ + +L+ E E++ Q +AE R P + R + Sbjct: 1268 VTLDELVKAKLEAQLNKDEGPTDREKLHQEAGEIK---QKIAELR-----PQLEAARTID 1319 Query: 302 DEEIIKLAER-----KRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIR 356 D +++ +R KR + AR+ + A R+ + ++ ++I+ Sbjct: 1320 DRQLVNKYQREFDELKRRQAHIGARIDADKASGNTFARETEIK-------RRQVQQEILD 1372 Query: 357 EADVVLTTNSSAALEV-----VDYDTYDVAIIDEATQSTIPSILIPLN-KVERFVLAGDH 410 +A V+ T S + E+ V+++T IIDEA Q S LIPL + +L GD Sbjct: 1373 KAQVLCATLSGSGHEMFKNLNVEFET---VIIDEAAQCVELSALIPLKYGCSKCILVGDP 1429 Query: 411 KQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKII 468 KQLPPT+LS A ++LF + + + +L QYRM+ I FP FY G + Sbjct: 1430 KQLPPTVLSQSAARYGYDQSLFVRMQKNHEKDVHLLDTQYRMHPEISSFPRAAFYEGLLQ 1489 Query: 469 ADESVRGITLRDLVEYQSPNDSWGK--ILNPENVIVFIDTSKAENKWERQRRGSESRENP 526 + + +S W + +L P F D ++ + + + E Sbjct: 1490 DGDDMA----------KSRLQPWHRSTLLGPYR---FFDVRGSQERGPKNQSLVNEEELK 1536 Query: 527 LEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQ----RDLISMK----VPEDVEVKTVDGY 578 + ++ + ++ +K + IG+ITPY Q R + + + +++E T D + Sbjct: 1537 VAMQLYRRFKADYGNVDLKGK-IGIITPYKAQLYRLRSQFAQRFGDAITDEIEFNTTDAF 1595 Query: 579 QGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMI 638 QGRE E+II S VR++ G IGF+ D+RR+NV LTRA+ L ++GDS L E + K+I Sbjct: 1596 QGRECEIIIFSCVRASPTGGIGFMTDIRRMNVGLTRARSSLWILGDSRALMQGEFWAKLI 1655 Query: 639 EFFKEK 644 E K + Sbjct: 1656 EDSKRR 1661 >gb|AAB63976.1| (M74589) SEN1 [Saccharomyces cerevisiae] Length = 2112 Score = 167 bits (419), Expect = 3e-40 Identities = 155/549 (28%), Positives = 259/549 (46%), Gaps = 84/549 (15%) Query: 161 EVNFVPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELI------------- 207 E+ V LN SQ +AI ++ E F L+ GP GTGKT+T++ +I Sbjct: 1206 EIETVKKSYKLNTSQAEAIVNSVSKEGFSLIQGPPGTGKTKTILGIIGYFLSTKNASSSN 1265 Query: 208 ------------RQEVKRGNKVLATAESNVAVDNLVERLSRSGI----------KIVRIG 245 +++ + K+L A SN AVD + RL +SG+ ++VR+G Sbjct: 1266 VIKVPLEKNSSNTEQLLKKQKILICAPSNAAVDEICLRL-KSGVYDKQGHQFKPQLVRVG 1324 Query: 246 HPSRVSKHLHETTLAYLITQ------HELYGELRELRVIGQSLAEKRDTYTKPTPKF--- 296 V+ + + TL L+ + +E+ + R ++ ++R+ K + Sbjct: 1325 RSDVVNVAIKDLTLEELVDKRIGERNYEIRTDPELERKFNNAVTKRRELRGKLDSESGNP 1384 Query: 297 RRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIAR-DII 355 +S E+I KL + R +++I E+ R+ R L+ R A+ I+ Sbjct: 1385 ESPMSTEDISKLQLKIREL----SKIINELGRDRDEMREKNSVNYRNRDLDRRNAQAHIL 1440 Query: 356 READVVLTTNSSAALEVVDYD--TYDVAIIDEATQSTIPSILIPLNKV-ERFVLAGDHKQ 412 +D++ +T S +A +V+ +D IIDEA Q T S +IPL +R ++ GD Q Sbjct: 1441 AVSDIICSTLSGSAHDVLATMGIKFDTVIIDEACQCTELSSIIPLRYGGKRCIMVGDPNQ 1500 Query: 413 LPPTILSLEAQELSRTLFEGLIERYPWKSE--MLVVQYRMNERIMEFPSKEFYGGKIIAD 470 LPPT+LS A + L R S +L VQYRM+ I +FPS EFY G++ Sbjct: 1501 LPPTVLSGAASNFKYN--QSLFVRMEKNSSPYLLDVQYRMHPSISKFPSSEFYQGRLKDG 1558 Query: 471 ESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAE 530 + + R W + L P F D + Q + S N E Sbjct: 1559 PGMDILNKRP----------WHQ-LEPLAPYKFFDIISGR---QEQNAKTMSYTNMEEIR 1604 Query: 531 IVAKIVDKLL-SIGVKPEW---IGVITPYDDQRDLISMK--------VPEDVEVKTVDGY 578 + ++VD L K ++ IG+I+PY +Q + + + + ++ T+DG+ Sbjct: 1605 VAIELVDYLFRKFDNKIDFTGKIGIISPYREQMQKMRKEFARYFGGMINKSIDFNTIDGF 1664 Query: 579 QGREKEVIILSLVRSNKL-GEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKM 637 QG+EKE+I++S VR++ +GFLKD RR+NV+LTRAK + V+G +L+ + ++ + Sbjct: 1665 QGQEKEIILISCVRADDTKSSVGFLKDFRRMNVALTRAKTSIWVLGHQRSLAKSKLWRDL 1724 Query: 638 IEFFKEKGC 646 IE K++ C Sbjct: 1725 IEDAKDRSC 1733 >gi|6323462 component of a nuclear-localized tRNA splicing complex; Sen1p [Saccharomyces cerevisiae] >gi|3123282|sp|Q00416|SEN1_YEAST TRNA-SPLICING ENDONUCLEASE POSITIVE EFFECTOR >gi|1078364|pir||S53416 SEN1 protein - yeast (Saccharomyces cerevisiae) >gi|664872|gb|AAB67502.1| (U20939) Sen1p [Saccharomyces cerevisiae] Length = 2231 Score = 167 bits (419), Expect = 3e-40 Identities = 155/549 (28%), Positives = 259/549 (46%), Gaps = 84/549 (15%) Query: 161 EVNFVPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELI------------- 207 E+ V LN SQ +AI ++ E F L+ GP GTGKT+T++ +I Sbjct: 1325 EIETVKKSYKLNTSQAEAIVNSVSKEGFSLIQGPPGTGKTKTILGIIGYFLSTKNASSSN 1384 Query: 208 ------------RQEVKRGNKVLATAESNVAVDNLVERLSRSGI----------KIVRIG 245 +++ + K+L A SN AVD + RL +SG+ ++VR+G Sbjct: 1385 VIKVPLEKNSSNTEQLLKKQKILICAPSNAAVDEICLRL-KSGVYDKQGHQFKPQLVRVG 1443 Query: 246 HPSRVSKHLHETTLAYLITQ------HELYGELRELRVIGQSLAEKRDTYTKPTPKF--- 296 V+ + + TL L+ + +E+ + R ++ ++R+ K + Sbjct: 1444 RSDVVNVAIKDLTLEELVDKRIGERNYEIRTDPELERKFNNAVTKRRELRGKLDSESGNP 1503 Query: 297 RRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIAR-DII 355 +S E+I KL + R +++I E+ R+ R L+ R A+ I+ Sbjct: 1504 ESPMSTEDISKLQLKIREL----SKIINELGRDRDEMREKNSVNYRNRDLDRRNAQAHIL 1559 Query: 356 READVVLTTNSSAALEVVDYD--TYDVAIIDEATQSTIPSILIPLNKV-ERFVLAGDHKQ 412 +D++ +T S +A +V+ +D IIDEA Q T S +IPL +R ++ GD Q Sbjct: 1560 AVSDIICSTLSGSAHDVLATMGIKFDTVIIDEACQCTELSSIIPLRYGGKRCIMVGDPNQ 1619 Query: 413 LPPTILSLEAQELSRTLFEGLIERYPWKSE--MLVVQYRMNERIMEFPSKEFYGGKIIAD 470 LPPT+LS A + L R S +L VQYRM+ I +FPS EFY G++ Sbjct: 1620 LPPTVLSGAASNFKYN--QSLFVRMEKNSSPYLLDVQYRMHPSISKFPSSEFYQGRLKDG 1677 Query: 471 ESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAE 530 + + R W + L P F D + Q + S N E Sbjct: 1678 PGMDILNKRP----------WHQ-LEPLAPYKFFDIISGR---QEQNAKTMSYTNMEEIR 1723 Query: 531 IVAKIVDKLL-SIGVKPEW---IGVITPYDDQRDLISMK--------VPEDVEVKTVDGY 578 + ++VD L K ++ IG+I+PY +Q + + + + ++ T+DG+ Sbjct: 1724 VAIELVDYLFRKFDNKIDFTGKIGIISPYREQMQKMRKEFARYFGGMINKSIDFNTIDGF 1783 Query: 579 QGREKEVIILSLVRSNKL-GEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKM 637 QG+EKE+I++S VR++ +GFLKD RR+NV+LTRAK + V+G +L+ + ++ + Sbjct: 1784 QGQEKEIILISCVRADDTKSSVGFLKDFRRMNVALTRAKTSIWVLGHQRSLAKSKLWRDL 1843 Query: 638 IEFFKEKGC 646 IE K++ C Sbjct: 1844 IEDAKDRSC 1852 >gb|AAG19799.1| (AE005064) DNA helicase; Hel [Halobacterium sp. NRC-1] Length = 821 Score = 167 bits (418), Expect = 4e-40 Identities = 109/287 (37%), Positives = 155/287 (53%), Gaps = 22/287 (7%) Query: 355 IREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLP 414 +R A VV T ++ ++ +DV ++DEA+Q T P L +N+ RFVL GDH+QLP Sbjct: 552 LRSAPVVAATTATCGSRILRELEFDVVLVDEASQLTEPDTLAAINRGARFVLVGDHEQLP 611 Query: 415 PTILSLEAQELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKI-IADESV 473 P + S LS++LFE L E YP S ML QYRM++RI F S+EFY G++ A V Sbjct: 612 PVVRS--GGRLSKSLFERLHETYPEASVMLDQQYRMSQRIQAFSSREFYDGQLRPASSEV 669 Query: 474 RGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVA 533 G L D+ D G + + F D + ++ +P EA+ VA Sbjct: 670 AGQRLTDV-----GVDPGGAV---HGGVTFYDVPGTD----------DAHVDPAEADRVA 711 Query: 534 KIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRS 593 +V + G+ P IGVI P+ Q I + P V V TVD +QG KEVI++S V Sbjct: 712 DVVTAYVDAGLDPGEIGVIAPFRAQVAEIGRRTPAGVAVDTVDRFQGSSKEVIVVSFVAR 771 Query: 594 NKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEF 640 L E +D RR+NV+L+RAK+ L++VGD L S Y +MI++ Sbjct: 772 GTL-EGPIFEDHRRVNVALSRAKKSLVLVGDERALRSEPLYDRMIDW 817 Score = 86.2 bits (210), Expect = 1e-15 Identities = 81/283 (28%), Positives = 137/283 (47%), Gaps = 12/283 (4%) Query: 5 SFINRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGE-ELGYFLVKY 63 ++ + L + +E ER A + R ++ S ER RA++ L+ E G + + Sbjct: 289 AYFDELYDAIEAERGAIHDEYR-KLWEQSPDERAADDRAVVGLSPAEQTELPDGRWRLTA 347 Query: 64 GRNREIKTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVALETVPEWALRDVRIDLY 123 R ++I GD V+ S DP+ VE R +E + + R+D+Y Sbjct: 348 TRPGSAASKIREGDRVLASDGDPVAGRAEMARVE---RLDADRVEVTTDEPVSLCRLDVY 404 Query: 124 ANDITFRRWLENLN-TIKKAGKRALRFYLGLDEPS-QGEEVNFVPFDKSLNRSQRKAISK 181 ++++ R L L+ + K+ +R P +G + + +P N +Q A+++ Sbjct: 405 PSELSVDRMLTALHDAVLKSDQRRTDLLFDRASPRFEGGDHDLIPN----NDAQNAAVNR 460 Query: 182 ALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLSRSGIK- 240 AL +EDF LVHGP GTGKT T+ L++ V RG++VL +A +N AVDN ++ L + G + Sbjct: 461 ALNAEDFALVHGPPGTGKTYTIATLVQAFVARGDRVLVSAFTNRAVDNALDALRQQGHED 520 Query: 241 IVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLA 283 IVR+G + V + + L E LR V+ + A Sbjct: 521 IVRVGTETGVRADMQDLRLDRSGDPGERAAALRSAPVVAATTA 563 >gi|6321024 DNA Helicase I; Ecm32p [Saccharomyces cerevisiae] >gi|418429|sp|P32644|YE06_YEAST HYPOTHETICAL 127.0 KD PROTEIN IN RAD24-BMH1 INTERGENIC REGION >gi|320741|pir||S30862 DNA dependent ATPase/DNA helicase B - yeast (Saccharomyces cerevisiae) >gi|603417|gb|AAB64703.1| (U18922) Yer176wp [Saccharomyces cerevisiae] Length = 1121 Score = 161 bits (402), Expect = 3e-38 Identities = 157/531 (29%), Positives = 238/531 (44%), Gaps = 125/531 (23%) Query: 171 LNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNK--VLATAESNVAVD 228 LNRSQ+ A+ L + ++ GP GTGKT T+ E+I Q ++R + +L A SN+A+D Sbjct: 649 LNRSQKTAVEHVLNNS-ITILQGPPGTGKTSTIEEIIIQVIERFHAFPILCVAASNIAID 707 Query: 229 NLVERL--SRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELR-ELRVIGQSLAEK 285 N+ E++ +R IKI+RI + ++ + L + + +Y L +++V+ Sbjct: 708 NIAEKIMENRPQIKILRILSKKKEQQYSDDHPLGEICLHNIVYKNLSPDMQVVAN----- 762 Query: 286 RDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARK 345 K RRG E+I +E + K Sbjct: 763 ---------KTRRG----EMISKSEDTK-----------------------------FYK 780 Query: 346 LEERIARDIIREADVVLTTNSSAA-LEVVDYDTYDVAIIDEATQSTIPSILIPLNK--VE 402 + R+ ++ ++ ++ TTN +A E+ V I+DEATQS+ S L+PL+ + Sbjct: 781 EKNRVTNKVVSQSQIIFTTNIAAGGRELKVIKECPVVIMDEATQSSEASTLVPLSLPGIR 840 Query: 403 RFVLAGDHKQLPPTILSLEAQELSRTLFEGLIERYPWKSE-MLVVQYRMNERIMEFPSKE 461 FV GD KQL +L +LFE ++ +K+ ML QYRM+ +I EFP K+ Sbjct: 841 NFVFVGDEKQLSSFS---NIPQLETSLFERVLSNGTYKNPLMLDTQYRMHPKISEFPIKK 897 Query: 462 FYGGKI---IADESVR--GITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQ 516 Y G++ + DE G+ L YQ ++ + + IV ENK E Sbjct: 898 IYNGELKDGVTDEQKAWPGVQ-HPLFFYQCDLGPESRVRSTQRDIVGF---TYENKHEC- 952 Query: 517 RRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLIS------------- 563 EIV I +L V E IGVITPY QRDL+S Sbjct: 953 ------------VEIVKIIQILMLDKKVPLEEIGVITPYSAQRDLLSDILTKNVVINPKQ 1000 Query: 564 -----------------------------MKVPEDVEVKTVDGYQGREKEVIILSLVRSN 594 + + + V TVD +QG EK II S VR+N Sbjct: 1001 ISMQQEYDEIELFNAAGSQGTAGSLQNNVINIINGLHVATVDSFQGHEKSFIIFSCVRNN 1060 Query: 595 KLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHE-TYKKMIEFFKEK 644 +IGFL+D RRLNV+LTRAK LIVVG+ + L + +K I + +E+ Sbjct: 1061 TENKIGFLRDKRRLNVALTRAKHGLIVVGNKNVLRKGDPLWKDYITYLEEQ 1111 >pir||T39568 hypothetical helicase - fission yeast (Schizosaccharomyces pombe) >gi|4481950|emb|CAB38508.1| (AL035637) dna replication helicase [Schizosaccharomyces pombe] Length = 1398 Score = 159 bits (397), Expect = 1e-37 Identities = 106/318 (33%), Positives = 168/318 (52%), Gaps = 22/318 (6%) Query: 340 FDDARKLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLN 399 FDD L+ + +V ++ + + +D IIDEA+Q +P L PL Sbjct: 1027 FDDLASLKH-----FYEDPQIVACSSLGVYHSIFNKRKFDYCIIDEASQIPLPICLGPLQ 1081 Query: 400 KVERFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEF 457 E+FVL GDH QLPP + + + LS +LF+ L E++P L +QYRMNE I Sbjct: 1082 LAEKFVLVGDHYQLPPLVKNSRTSKDGLSLSLFKLLSEKHPEAVTTLRLQYRMNEDINSL 1141 Query: 458 PSKEFYGGKIIADES--------VRGITLRDLVEYQSPNDSW-GKILNPENVIVFIDTSK 508 S+ YGG ++ + L D + S + W K++NP + ++F +T Sbjct: 1142 SSELIYGGNLVCGSKTISQKKLILPKAHLSDGLPDSSSSLHWVNKLINPSHSVIFFNT-- 1199 Query: 509 AENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLIS--MKV 566 ++ + + + EN EA ++ + V L GVK IG+I+ Y Q +L+S +K Sbjct: 1200 -DDILGVESKTNNILENHTEAFLIEQAVSSFLERGVKQSSIGIISIYKSQVELLSKNLKS 1258 Query: 567 PEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIG-FLKDLRRLNVSLTRAKRKLIVVGDS 625 ++E+ TVD YQGR+K++I++S VRSN +G L+D RLNV+L+RAK K I+ G Sbjct: 1259 FTEIEINTVDRYQGRDKDIILISFVRSNSKNLVGELLRDWHRLNVALSRAKVKCIMFGSL 1318 Query: 626 STLSSHETYKKMIEFFKE 643 STLSS +++ ++ Sbjct: 1319 STLSSSNIVSHLLKLLEK 1336 >pir||T51292 Dna2p - fission yeast (Schizosaccharomyces pombe) >gi|5052396|gb|AAD38528.1|AF144384_1 (AF144384) Dna2p [Schizosaccharomyces pombe] Length = 1397 Score = 159 bits (397), Expect = 1e-37 Identities = 106/318 (33%), Positives = 168/318 (52%), Gaps = 22/318 (6%) Query: 340 FDDARKLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLN 399 FDD L+ + +V ++ + + +D IIDEA+Q +P L PL Sbjct: 1026 FDDLASLKH-----FYEDPQIVACSSLGVYHSIFNKRKFDYCIIDEASQIPLPICLGPLQ 1080 Query: 400 KVERFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEF 457 E+FVL GDH QLPP + + + LS +LF+ L E++P L +QYRMNE I Sbjct: 1081 LAEKFVLVGDHYQLPPLVKNSRTSKDGLSLSLFKLLSEKHPEAVTTLRLQYRMNEDINSL 1140 Query: 458 PSKEFYGGKIIADES--------VRGITLRDLVEYQSPNDSW-GKILNPENVIVFIDTSK 508 S+ YGG ++ + L D + S + W K++NP + ++F +T Sbjct: 1141 SSELIYGGNLVCGSKTISQKKLILPKAHLSDGLPDSSSSLHWVNKLINPSHSVIFFNT-- 1198 Query: 509 AENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLIS--MKV 566 ++ + + + EN EA ++ + V L GVK IG+I+ Y Q +L+S +K Sbjct: 1199 -DDILGVESKTNNILENHTEAFLIEQAVSSFLERGVKQSSIGIISIYKSQVELLSKNLKS 1257 Query: 567 PEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIG-FLKDLRRLNVSLTRAKRKLIVVGDS 625 ++E+ TVD YQGR+K++I++S VRSN +G L+D RLNV+L+RAK K I+ G Sbjct: 1258 FTEIEINTVDRYQGRDKDIILISFVRSNSKNLVGELLRDWHRLNVALSRAKVKCIMFGSL 1317 Query: 626 STLSSHETYKKMIEFFKE 643 STLSS +++ ++ Sbjct: 1318 STLSSSNIVSHLLKLLEK 1335 >gb|AAF99770.1|AC003981_20 (AC003981) F22O13.33 [Arabidopsis thaliana] Length = 865 Score = 158 bits (396), Expect = 2e-37 Identities = 117/326 (35%), Positives = 171/326 (51%), Gaps = 26/326 (7%) Query: 312 KRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREADVVLTTNSSAALE 371 K R LS +++E + K +V AF D +K +++ VV +T Sbjct: 508 KNTCRELSFYVLVETRLYTKKFEKV--AFQDIKKKLDQVK--------VVASTCLGINSP 557 Query: 372 VVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSLEAQE--LSRTL 429 ++ +DV IIDEA Q +P + PL FVL GDH QLPP + S EA+E + +L Sbjct: 558 LLVNRRFDVCIIDEAGQIALPVSIGPLLFASTFVLVGDHYQLPPLVQSTEARENGMGISL 617 Query: 430 FEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADES-VRGITLRDLVEYQSPN 488 F L E +P +L QYRM IME + YG ++ + V TL ++ S Sbjct: 618 FRRLSEAHPQAISVLQNQYRMCRGIMELSNALIYGDRLCCGSAEVADATL--VLSTSSST 675 Query: 489 DSW-GKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPE 547 W K+L P +VF++T + R + NP+EA I+A ++L++ GV + Sbjct: 676 SPWLKKVLEPTRTVVFVNTDMLR---AFEARDQNAINNPVEASIIA---EELVNNGVDSK 729 Query: 548 WIGVITPYDDQRDLISMKVP-EDVEVKTVDGYQGREKEVIILSLVRSN---KLGEIGFLK 603 IG+ITPY+ Q LI +P VE+ T+D YQGR+K+ I++S VRS + L Sbjct: 730 DIGIITPYNSQASLIQHAIPTTPVEIHTIDKYQGRDKDCILVSFVRSREKPRSSASSLLG 789 Query: 604 DLRRLNVSLTRAKRKLIVVGDSSTLS 629 D R+NV+LTRAK+KLI+VG TLS Sbjct: 790 DWHRINVALTRAKKKLIMVGSQRTLS 815 >sp|P51530|Y083_HUMAN HYPOTHETICAL PROTEIN KIAA0083 >gi|11360302|pir||T50697 hypothetical protein KIAA0083 [imported] - human (fragment) >gi|1531548|dbj|BAA07647.1| (D42046) The ha3631 gene product is related to S.cerevisiae protein encoded in chromosome VIII. [Homo sapiens] Length = 1077 Score = 158 bits (395), Expect = 2e-37 Identities = 110/310 (35%), Positives = 166/310 (53%), Gaps = 22/310 (7%) Query: 360 VVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILS 419 +V TT + +D I+DEA+Q + P L PL RFVL GDH+QLPP +L+ Sbjct: 755 IVATTCMGINHPIFSRKIFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLN 814 Query: 420 LEAQEL--SRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKI------IADE 471 EA+ L S +LF+ L E+ L VQYRMN +IM +K Y GK+ +A+ Sbjct: 815 REARALGMSESLFKRL-EQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANA 873 Query: 472 SVRGITLRDL---VEY---QSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESREN 525 + +D+ +E+ S N + P N + F++T K E+ +G S N Sbjct: 874 VINLRHFKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAP-EQVEKGGVS--N 930 Query: 526 PLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPED---VEVKTVDGYQGRE 582 EA+++ + + G P IG+I PY Q +I+ + VEV TVD YQGR+ Sbjct: 931 VTEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRD 990 Query: 583 KEVIILSLVRSNKLGEIG-FLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFF 641 K ++++S VRSNK G +G LKD RRLNV++TRAK KLI++G +L+ + +K++ Sbjct: 991 KSIVLVSFVRSNKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHL 1050 Query: 642 KEKGCFIEFP 651 + I+ P Sbjct: 1051 NSEKLIIDLP 1060 >pir||T08986 hypothetical protein F6G3.130 - Arabidopsis thaliana >gi|4938486|emb|CAB43845.1| (AL078464) putative protein [Arabidopsis thaliana] >gi|7269910|emb|CAB81003.1| (AL161576) putative protein [Arabidopsis thaliana] Length = 1311 Score = 157 bits (392), Expect = 5e-37 Identities = 147/482 (30%), Positives = 235/482 (48%), Gaps = 64/482 (13%) Query: 216 KVLATAESNVAVDNLVERLSRSGI----------KIVRIGHPSRVSKHL-----HETTLA 260 ++L A SN A D L+ R+ G + R+G ++ + L Sbjct: 743 RMLVCAPSNAATDELLSRVLDRGFIDGEMRVYRPDVARVGVDTQTKAAQAVSVERRSDLL 802 Query: 261 YLITQHELYGELRELRVIGQSLAE-----KRDTYTKPTPKFRRGLS--DEEIIKLAERKR 313 ++ E+ G + LRV L++ KR+ +G D +++ + ++ R Sbjct: 803 LAKSREEILGHIHNLRVRDAQLSQDIAGLKRELTAAAFANRSQGSVGVDPDVLMVRDQTR 862 Query: 314 GA--RGLSARLIMEMAEWIKLNRQ--VQKAFDDARKLEERIAR-----DIIREADVVLTT 364 A + LSA + + ++++R V+ F AR EA++V TT Sbjct: 863 DAMLQRLSAVVEARDKDLVEMSRLLIVEGKFRAGTSFNLEEARASLEASFANEAEIVFTT 922 Query: 365 NSSAALEVVDYDT--YDVAIIDEATQSTIPSILIPLNK-VERFVLAGDHKQLPPTILSLE 421 SS+ ++ T +D+ +IDEA Q++ +L PL R VL GD +QLP T++S Sbjct: 923 VSSSGRKLFSRLTHGFDMVVIDEAAQASEVGVLPPLALGAARCVLVGDPQQLPATVISKA 982 Query: 422 AQEL--SRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLR 479 A L SR+LFE + + +L VQYRM+ +I +FPS+ FY G++ ESV T Sbjct: 983 AGTLLYSRSLFERF-QLAGCPTLLLTVQYRMHPQIRDFPSRYFYQGRLTDSESVS--TAP 1039 Query: 480 DLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAE----IVAKI 535 D + Y+ +L P +F D S E R GS S EN EA + + Sbjct: 1040 DEIYYKD------SVLKP---YLFFDISHGR---ESHRGGSVSYENIDEARFCVGVYLHL 1087 Query: 536 VDKLLSIGVKPEWIGVITPYDDQR--------DLISMKVPEDVEVKTVDGYQGREKEVII 587 L S+G +GVITPY Q + +S +++ + TVD +QG+E++VII Sbjct: 1088 QRTLKSLGGGKVSVGVITPYKLQLKCLKIEFGNALSQDELQEIYINTVDAFQGQERDVII 1147 Query: 588 LSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGCF 647 +S VR++ G +GF+ D+RR+NV+LTRAKR L V+G++S L E + +I K + CF Sbjct: 1148 MSCVRASNHG-VGFVADIRRMNVALTRAKRALWVMGNASALMKCEDWAALITDAKARNCF 1206 Query: 648 IE 649 +E Sbjct: 1207 ME 1208 >pir||T26415 hypothetical protein Y106G6D.5 - Caenorhabditis elegans >gi|3880678|emb|CAA20978.1| (AL031629) cDNA EST EMBL:T00167 comes from this gene~cDNA EST yk384f3.3 comes from this gene~cDNA EST yk287a1.5 comes from this gene~cDNA EST yk384f3.5 comes from this gene [Caenorhabditis elegans] Length = 693 Score = 153 bits (383), Expect = 5e-36 Identities = 97/294 (32%), Positives = 168/294 (56%), Gaps = 16/294 (5%) Query: 360 VVLTTNSSAALEVVDYD-TYDVAIIDEATQSTIPSILIPL---NKVERFVLAGDHKQLPP 415 V T +S+ ++ +Y DV I+DEA Q T P+ +P+ ++ +L GD KQLP Sbjct: 381 VFSTLGTSSIQKLPEYHWNADVMIVDEAAQCTEPATWVPVLTTPSCKKLILVGDQKQLPA 440 Query: 416 TILSLEAQE--LSRTLFEGLIERYPWKSEMLVV--QYRMNERIMEFPSKEFYGGKIIADE 471 +LS +A + +L E L E + + +++ QYRMN++IM + ++ FY ++ A Sbjct: 441 VVLSDKAMKGNFKLSLMEKLAEEFSSNNINILLNEQYRMNKKIMNWSNEVFYENQLTAHS 500 Query: 472 SVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEI 531 +V ITLRD+ PN +LN N I+ I+ +++ + S S N E + Sbjct: 501 TVSDITLRDIC----PNLPEDHVLN--NPIMMINMENVKDR-SHEEFESHSFTNTDELNL 553 Query: 532 VAKIVDKLL-SIGVKPEWIGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSL 590 V + V++L+ +G+ P+ I VI+PY Q + + +P V+V TVD +QG E++V+I L Sbjct: 554 VTEYVNRLVVDLGINPKAIAVISPYYAQIEKLRRSIPFRVDVNTVDAFQGHERQVVIFCL 613 Query: 591 VRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEK 644 VR N G+IGFL + RRLNV++TRA+R+ +++G+ + ++ K+ + + + Sbjct: 614 VRDNDEGQIGFLNETRRLNVAVTRARRQFVLIGNGRMMKGNKHLLKLYKHLQSE 667 >pir||T00533 SEN1 protein homolog T20K24.14 - Arabidopsis thaliana >gi|3176714|gb|AAD12029.1| (AC002392) putative DNA2-NAM7 helicase family protein [Arabidopsis thaliana] Length = 1090 Score = 152 bits (379), Expect = 2e-35 Identities = 147/483 (30%), Positives = 236/483 (48%), Gaps = 66/483 (13%) Query: 216 KVLATAESNVAVDNLVERLSRSGI----------KIVRIGHPSR------VSKHLHETTL 259 ++L A SN A D L+ R+ G + R+G S+ VS L Sbjct: 580 RMLVCAPSNAATDELLSRVLDRGFIDGEMRVYRPDVARVGVDSQSRAAQAVSVERRSDQL 639 Query: 260 AYLITQHELYGELRELRV----IGQSLAE-KRDTYTKPTPKFRRGLS--DEEIIKLAERK 312 I++ E+ +R LR+ I Q++A KR+ +G D E++ ++K Sbjct: 640 L-AISRDEILRHMRNLRLQETQISQNIAGLKRELNAAAFATRSQGSVGVDPEVLISRDQK 698 Query: 313 RGARGLSARLIMEMAE--WIKLNRQ--VQKAFDDARKLEERIAR-----DIIREADVVLT 363 R A ++E + ++++R V+ F AR EA++V T Sbjct: 699 RDALLQHLAAVVEARDKVLVEISRLLIVEGKFRAGNNFNLEEARASLEASFANEAEIVFT 758 Query: 364 TNSSAALEVVDYDT--YDVAIIDEATQSTIPSILIPLNK-VERFVLAGDHKQLPPTILSL 420 T SS+ ++ T +D+ +IDEA Q++ +L PL R VL GD +QLP T++S Sbjct: 759 TVSSSGRKLFSRLTHGFDMVVIDEAAQASEVGVLPPLALGAARCVLVGDPQQLPATVISK 818 Query: 421 EAQEL--SRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITL 478 A L SR+LFE + + +L VQYRM+ +I +FPS+ FY G++ ES+ Sbjct: 819 AAGTLLYSRSLFERF-QLAGCPTLLLTVQYRMHPQIRDFPSRYFYQGRLKDSESISSAP- 876 Query: 479 RDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAE----IVAK 534 D + Y+ P +L P +F + S E R GS S EN EA + Sbjct: 877 -DEIYYKDP------VLRP---YLFFNISHGR---ESHRGGSVSYENVDEARFCVGVYMH 923 Query: 535 IVDKLLSIGVKPEWIGVITPYDDQRDLISMKVP--------EDVEVKTVDGYQGREKEVI 586 + L S+G +GVITPY Q + + +++ + TVD +QG+E++VI Sbjct: 924 LQKTLKSLGAGKVSVGVITPYKLQLKCLKHEFGNALGQDELKEIYINTVDAFQGQERDVI 983 Query: 587 ILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGC 646 I+S VR++ G +GF+ D+RR+NV+LTRA+R L V+G++S L E + +I + + C Sbjct: 984 IMSCVRASGHG-VGFVSDIRRMNVALTRARRALWVMGNASALMKSEDWAALISDARGRNC 1042 Query: 647 FIE 649 F+E Sbjct: 1043 FME 1045 >dbj|BAA31600.1| (AB014525) KIAA0625 protein [Homo sapiens] Length = 791 Score = 148 bits (369), Expect = 2e-34 Identities = 143/561 (25%), Positives = 255/561 (44%), Gaps = 115/561 (20%) Query: 165 VPFDKSLNRSQRKAISKALGS-------EDFFLVHGPFGTGKTRTLV----ELIRQEVKR 213 + + + N Q+KAI A L+HGP GTGK++T+V L+ + ++ Sbjct: 42 IAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRK 101 Query: 214 G------------NKVLATAESNVAVDNLVERL----------------SRSGIKIVRIG 245 G N+VL A SN AVD L++++ + I +VR+G Sbjct: 102 GHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLG 161 Query: 246 HPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGLSDEEI 305 K ++ L + + + +EL Q++ ++++ D ++ Sbjct: 162 P----EKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKE------------FLDYQL 205 Query: 306 IKLAERKRGARGLSARLIMEMAEWI-KLNRQVQKAFDDARKLEERIARD---IIREADVV 361 +L+ ++ RG E+ E I K++++ Q+ ++++ R + II E+ ++ Sbjct: 206 DELSRQRALCRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHII 265 Query: 362 LTTNSSAALEVVDYD-------TYDVAIIDEATQSTIPSILIPL-NKVERFVLAGDHKQL 413 T S++ +++ + I+DEA QS L PL ++ + +L GD KQL Sbjct: 266 CCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQL 325 Query: 414 PPTILSLEAQE--------------LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPS 459 PPT++S++AQE L + +I R P L VQYRM+ I FPS Sbjct: 326 PPTVISMKAQEYGYDQSMMARFCRLLEENVEHNMISRLPILQ--LTVQYRMHPDICLFPS 383 Query: 460 KEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRG 519 Y + + I + W P + D +RR Sbjct: 384 NYVYNRNLKTNRQTEAIRC---------SSDW-----PFQPYLVFDVGDGS-----ERRD 424 Query: 520 SESRENPLEAEIVAKIV----DKLLSIGVKPEWIGVITPYDDQRDLISMKVPED------ 569 ++S N E ++V +I+ DK + + IG+IT Y Q+ +I + ++ Sbjct: 425 NDSYINVQEIKLVMEIIKLIKDKRKDVSFRN--IGIITHYKAQKTMIQKDLDKEFDRKGP 482 Query: 570 VEVKTVDGYQGREKEVIILSLVRSNKL-GEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL 628 EV TVD +QGR+K+ +I++ VR+N + G IGFL L+RLNV++TRAK L ++G TL Sbjct: 483 AEVDTVDAFQGRQKDCVIVTCVRANSIQGSIGFLASLQRLNVTITRAKYSLFILGHLRTL 542 Query: 629 SSHETYKKMIEFFKEKGCFIE 649 ++ + ++I+ +++G I+ Sbjct: 543 MENQHWNQLIQDAQKRGAIIK 563 >gi|7662212 KIAA0625 protein [Homo sapiens] >gi|7022724|dbj|BAA91701.1| (AK001456) unnamed protein product [Homo sapiens] Length = 828 Score = 148 bits (369), Expect = 2e-34 Identities = 143/561 (25%), Positives = 255/561 (44%), Gaps = 115/561 (20%) Query: 165 VPFDKSLNRSQRKAISKALGS-------EDFFLVHGPFGTGKTRTLV----ELIRQEVKR 213 + + + N Q+KAI A L+HGP GTGK++T+V L+ + ++ Sbjct: 79 IAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRK 138 Query: 214 G------------NKVLATAESNVAVDNLVERL----------------SRSGIKIVRIG 245 G N+VL A SN AVD L++++ + I +VR+G Sbjct: 139 GHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLG 198 Query: 246 HPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGLSDEEI 305 K ++ L + + + +EL Q++ ++++ D ++ Sbjct: 199 P----EKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKE------------FLDYQL 242 Query: 306 IKLAERKRGARGLSARLIMEMAEWI-KLNRQVQKAFDDARKLEERIARD---IIREADVV 361 +L+ ++ RG E+ E I K++++ Q+ ++++ R + II E+ ++ Sbjct: 243 DELSRQRALCRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHII 302 Query: 362 LTTNSSAALEVVDYD-------TYDVAIIDEATQSTIPSILIPL-NKVERFVLAGDHKQL 413 T S++ +++ + I+DEA QS L PL ++ + +L GD KQL Sbjct: 303 CCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQL 362 Query: 414 PPTILSLEAQE--------------LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPS 459 PPT++S++AQE L + +I R P L VQYRM+ I FPS Sbjct: 363 PPTVISMKAQEYGYDQSMMARFCRLLEENVEHNMISRLPILQ--LTVQYRMHPDICLFPS 420 Query: 460 KEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRG 519 Y + + I + W P + D +RR Sbjct: 421 NYVYNRNLKTNRQTEAIRC---------SSDW-----PFQPYLVFDVGDGS-----ERRD 461 Query: 520 SESRENPLEAEIVAKIV----DKLLSIGVKPEWIGVITPYDDQRDLISMKVPED------ 569 ++S N E ++V +I+ DK + + IG+IT Y Q+ +I + ++ Sbjct: 462 NDSYINVQEIKLVMEIIKLIKDKRKDVSFRN--IGIITHYKAQKTMIQKDLDKEFDRKGP 519 Query: 570 VEVKTVDGYQGREKEVIILSLVRSNKL-GEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL 628 EV TVD +QGR+K+ +I++ VR+N + G IGFL L+RLNV++TRAK L ++G TL Sbjct: 520 AEVDTVDAFQGRQKDCVIVTCVRANSIQGSIGFLASLQRLNVTITRAKYSLFILGHLRTL 579 Query: 629 SSHETYKKMIEFFKEKGCFIE 649 ++ + ++I+ +++G I+ Sbjct: 580 MENQHWNQLIQDAQKRGAIIK 600 >gi|11429653 KIAA0625 protein [Homo sapiens] Length = 916 Score = 148 bits (369), Expect = 2e-34 Identities = 143/561 (25%), Positives = 255/561 (44%), Gaps = 115/561 (20%) Query: 165 VPFDKSLNRSQRKAISKALGS-------EDFFLVHGPFGTGKTRTLV----ELIRQEVKR 213 + + + N Q+KAI A L+HGP GTGK++T+V L+ + ++ Sbjct: 167 IAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRK 226 Query: 214 G------------NKVLATAESNVAVDNLVERL----------------SRSGIKIVRIG 245 G N+VL A SN AVD L++++ + I +VR+G Sbjct: 227 GHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLG 286 Query: 246 HPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGLSDEEI 305 K ++ L + + + +EL Q++ ++++ D ++ Sbjct: 287 P----EKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKE------------FLDYQL 330 Query: 306 IKLAERKRGARGLSARLIMEMAEWI-KLNRQVQKAFDDARKLEERIARD---IIREADVV 361 +L+ ++ RG E+ E I K++++ Q+ ++++ R + II E+ ++ Sbjct: 331 DELSRQRALCRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHII 390 Query: 362 LTTNSSAALEVVDYD-------TYDVAIIDEATQSTIPSILIPL-NKVERFVLAGDHKQL 413 T S++ +++ + I+DEA QS L PL ++ + +L GD KQL Sbjct: 391 CCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQL 450 Query: 414 PPTILSLEAQE--------------LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPS 459 PPT++S++AQE L + +I R P L VQYRM+ I FPS Sbjct: 451 PPTVISMKAQEYGYDQSMMARFCRLLEENVEHNMISRLPILQ--LTVQYRMHPDICLFPS 508 Query: 460 KEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRG 519 Y + + I + W P + D +RR Sbjct: 509 NYVYNRNLKTNRQTEAIRC---------SSDW-----PFQPYLVFDVGDGS-----ERRD 549 Query: 520 SESRENPLEAEIVAKIV----DKLLSIGVKPEWIGVITPYDDQRDLISMKVPED------ 569 ++S N E ++V +I+ DK + + IG+IT Y Q+ +I + ++ Sbjct: 550 NDSYINVQEIKLVMEIIKLIKDKRKDVSFRN--IGIITHYKAQKTMIQKDLDKEFDRKGP 607 Query: 570 VEVKTVDGYQGREKEVIILSLVRSNKL-GEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL 628 EV TVD +QGR+K+ +I++ VR+N + G IGFL L+RLNV++TRAK L ++G TL Sbjct: 608 AEVDTVDAFQGRQKDCVIVTCVRANSIQGSIGFLASLQRLNVTITRAKYSLFILGHLRTL 667 Query: 629 SSHETYKKMIEFFKEKGCFIE 649 ++ + ++I+ +++G I+ Sbjct: 668 MENQHWNQLIQDAQKRGAIIK 688 >gb|AAG20303.1| (AE005104) DNA binding protein eukaryotic-like; Dbp [Halobacterium sp. NRC-1] Length = 751 Score = 147 bits (367), Expect = 4e-34 Identities = 105/309 (33%), Positives = 163/309 (51%), Gaps = 45/309 (14%) Query: 344 RKLEERIARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVER 403 R +++ + + ADVV T + AA D + +D+A++DEATQ++ + I +N + Sbjct: 442 RVVDDHYRQRGVDAADVVAATTNGAA--TFDQNAFDLAVVDEATQASRAATAIAVNAADT 499 Query: 404 FVLAGDHKQLPP-TILSLEAQELSRTLFEGLIERYPWKSEMLVV-QYRMNERIMEFPSKE 461 VLAGDH+QLPP + A E+ +LFE LI+RY +L+ QYRM++ I FP++ Sbjct: 500 LVLAGDHRQLPPYGVREGGAGEMRPSLFETLIDRYGDDVAVLLARQYRMHDAIAGFPNEA 559 Query: 462 FYGGK-----IIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQ 516 FYGG+ + AD +V G+ + +D + E R Sbjct: 560 FYGGRLETAAVAADRAVDGLP----------------------PVAVVDVAGQE---RRD 594 Query: 517 RRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE------DV 570 RG+ R N EA +VA VD + GV+P +GVI Y D I + + + Sbjct: 595 ERGASVR-NAAEASVVADRVDTIRRAGVEPGDLGVIAAYSDHVSAIRGVLADRGLDRPAL 653 Query: 571 EVKTVDGYQGREKEVIILSLVRSNKLGEIGFLK----DLRRLNVSLTRAKRKLIVVGDSS 626 V TVD +QG E++ +++S RSN + GFL+ RRLNV+LTRA+R L +VGD + Sbjct: 654 TVDTVDSFQGGERDAVVVSFARSNDAHDAGFLEHPAAGPRRLNVALTRARRHLSLVGDWA 713 Query: 627 TLSSHETYK 635 TL+ +++ Sbjct: 714 TLTDPASHR 722 >gb|AAF23837.1|AC007234_9 (AC007234) F1E22.14 [Arabidopsis thaliana] Length = 1076 Score = 142 bits (354), Expect = 1e-32 Identities = 110/352 (31%), Positives = 180/352 (50%), Gaps = 31/352 (8%) Query: 314 GARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIREADVVLTTNSSAALEVV 373 G+ S++ + +++KL R + + F + + +++ +L + +S + + Sbjct: 500 GSDRFSSQHVTVEDDYLKLLRSIPEIFPLPAVSDRHLIKELCLGHACLLFSTASCSARLY 559 Query: 374 DYDTYDVAIIDEATQ--STIPSILIPLNKVERFVLAGDHKQLPPTILSLEAQE--LSRTL 429 + +IDEA Q SI + L + +L GD +QLP + S A E R+L Sbjct: 560 TGTPIQLLVIDEAAQLKECESSIPMQLPGLRHLILVGDERQLPAMVESQIALEAGFGRSL 619 Query: 430 FEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPND 489 FE L K ML +QYRM+ I FP+KE YG KI+ +VR R+ + P + Sbjct: 620 FERLA-LLGHKKYMLNIQYRMHCSISSFPNKELYGKKILDAPTVRQ---RNYTKQYLPGE 675 Query: 490 SWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEW- 548 +G P + I + A + E S +N +E +VA I+ LL + K + Sbjct: 676 MYG----PYSFI-----NIAYGREEYGEGEGRSLKNNVEVVVVAAIIANLLQVSEKTKTR 726 Query: 549 --IGVITPYDDQRDLISMKVPE----------DVEVKTVDGYQGREKEVIILSLVRSNKL 596 +GVI+PY Q I K+ E + ++TVDG+QG E+++II+S VRSN + Sbjct: 727 INVGVISPYKAQVIAIQEKIQETSIGDAGGLFSLRIRTVDGFQGGEEDIIIVSTVRSNGV 786 Query: 597 GEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL-SSHETYKKMIEFFKEKGCF 647 G +GFL + RR NV LTRA+ L ++G+ +TL +S ++ +I+ KE+GCF Sbjct: 787 GRVGFLGNRRRTNVLLTRARFCLWILGNEATLMNSKSVWRNLIQDAKERGCF 838 >gb|AAG09081.1|AC026237_2 (AC026237) Similar to tRNA-splicing endonuclease positive effector SEN1 [Arabidopsis thaliana] Length = 2142 Score = 138 bits (345), Expect = 1e-31 Identities = 138/513 (26%), Positives = 222/513 (42%), Gaps = 97/513 (18%) Query: 216 KVLATAESNVAVDNLVERLSRSGIK----------IVRIGHPSRVSKHLHETTLAYLITQ 265 +VL A+SN AVD LV R+S GI +VR+G+ V + L L+ Q Sbjct: 1306 RVLICAQSNAAVDELVSRISSLGIYGRDGKMFKPYLVRVGNAKTVHSNSMPFFLDTLVDQ 1365 Query: 266 HELYGELR------------------ELRVIGQSLA-----------EKRDTYTKPTPKF 296 +R L + + E D KP + Sbjct: 1366 RLAEERMRINESKSNKGADSSALLRSNLEKVVDQITHFEAKRANINQESLDAKDKPENEH 1425 Query: 297 RRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIARDIIR 356 D +++ AE R L + + + Q +KA + R L++++ + I++ Sbjct: 1426 HNKDDDGKLMSDAELGIRLRRLYEQKRKIYKDLSAVQAQERKANYEMRTLKQKLRKSILK 1485 Query: 357 EADVVLTTNSSAALEVVDY----------------DTYDVAIIDEATQSTIPSILIPLNK 400 EA +V+TT S ++ + +D +IDEA Q+ P+ LIPL Sbjct: 1486 EAQIVVTTLSGCGGDLYSVCAESLAAHKFGSPSEDNLFDAVVIDEAAQALEPATLIPLQL 1545 Query: 401 VE----RFVLAGDHKQLPPTILSLEAQEL--SRTLFEGLIERYPWKSEMLVVQYRMNERI 454 ++ + ++ GD KQLP T+LS A + ++FE L +R + ML QYRM+ I Sbjct: 1546 LKSRGTKCIMVGDPKQLPATVLSNVASKFLYECSMFERL-QRAGYPILMLTQQYRMHPEI 1604 Query: 455 MEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWE 514 FPS FY K++ G+ + N G VF D + E Sbjct: 1605 CRFPSMHFYDNKLL-----NGVDMSSKSAPFHENHHLGPY-------VFYDIVDGQ---E 1649 Query: 515 RQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEW----IGVITPYDDQRDLISMK----- 565 + S S N EAE +++ + E+ IG+ITPY Q ++ + Sbjct: 1650 HRSGDSSSVCNEQEAEAAVQLL-RFFKKRYPSEFVAGRIGIITPYKRQLAVLRSRFTGAF 1708 Query: 566 ---VPEDVEVKTVDGYQGREKEVIILSLVRSN-------KLGEIGFLKDLRRLNVSLTRA 615 V D+E+ TVDG+QG+E ++++LS VR+ IGF+ D+RR+NV+LTRA Sbjct: 1709 GAQVTADMEMNTVDGFQGKEVDILVLSTVRATHSAPDGVNQSRIGFVADVRRMNVALTRA 1768 Query: 616 KRKLIVVGDSSTLSSHETYKKMIEFFKEKGCFI 648 K L V+G++ TL + +++ KE+ I Sbjct: 1769 KLSLWVLGNTRTLQRDHNWGALVKDAKEREVII 1801 >gb|AAF50482.1| (AE003556) CG7504 gene product [Drosophila melanogaster] Length = 1417 Score = 137 bits (342), Expect = 3e-31 Identities = 136/485 (28%), Positives = 226/485 (46%), Gaps = 75/485 (15%) Query: 190 LVHGPFGTGKTRTLVELIRQEVKRGN-------KVLATAESNVAVDNLVERL-------S 235 L+ GP GTGK+R + EL Q + GN K+L A SN AVD++V L + Sbjct: 938 LIQGPPGTGKSRVISELCLQTLY-GNAAKTLDRKILICAHSNTAVDHIVGLLGSVLRVMN 996 Query: 236 RSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYTKPTPK 295 R ++R G ++S + + + + H + ++L+ + + AE K Sbjct: 997 RDQFHLLRFGMHEKMSHY----SRPFSLEAHFNKAKEQKLQRVSKENAEI-------LKK 1045 Query: 296 FRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDD--ARKLEERIARD 353 L DE + + K S L+ ++ + K + + ++ E I+ Sbjct: 1046 QHNDLKDE----IQQLKEKTNLTSTYLLQQLQQKEKKLQLISNQLSPPLTQREEFEISHM 1101 Query: 354 IIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLN-KVERFVLAGDHKQ 412 + A+++ TT SS D +D+ I+DEATQ T P L+P+ + VL GD +Q Sbjct: 1102 CVTRANIICTTLSSCVKLANYVDFFDICIVDEATQCTEPWTLLPMRFGLTHMVLVGDMQQ 1161 Query: 413 LPPTILSLEAQE--LSRTLFE-------------GLIERYPWKSEMLVVQYRMNERIMEF 457 LP +LS +A + LS ++F+ G K L QYRM+ I + Sbjct: 1162 LPAVVLSKKAIDFGLSNSMFDRIQRSLQTQLDKPGSYHLMHTKLFKLSTQYRMHPEICRW 1221 Query: 458 PSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQR 517 P++ FY ++I E + SP + I N+ D++ A+NK Sbjct: 1222 PNQYFYEDQLINAECT--------ARFASPLIPYCVI----NLKYTCDSNGAQNK----- 1264 Query: 518 RGSESRENPLEAEIVAKIVDKL-LSIGVKPEWIGVITPYDDQRDLISMKVPEDVEV--KT 574 S N EA VAK++ ++ + K G+I+PY +Q +S +P + + +T Sbjct: 1265 ----SISNNEEARFVAKLLTEMDKHMPSKRFSYGLISPYQNQCYALSQVIPSHMNITPQT 1320 Query: 575 VDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETY 634 VD YQG EK+VII+S R+ GFL + +RLNV+LTR +R L++ G+ L S E + Sbjct: 1321 VDSYQGLEKDVIIISNARTR---GCGFLTNYQRLNVALTRPRRCLVICGNFEDLKSVEMW 1377 Query: 635 KKMIE 639 + +++ Sbjct: 1378 RNLLD 1382 >pir||T28788 hypothetical protein C41D11.7 - Caenorhabditis elegans >gi|2105497|gb|AAC48142.1| (AF003740) similar to mammalian DNA-binding proteins SMUBP-2 [Caenorhabditis elegans] Length = 633 Score = 136 bits (338), Expect = 1e-30 Identities = 156/594 (26%), Positives = 259/594 (43%), Gaps = 110/594 (18%) Query: 95 VVEKGKRFIVVALETVPEWALRDVRIDLYANDITFRRWLENLN----TIKKAGKRALRFY 150 ++E K+F LE V +W + V ++ N ++ N T++ + + Sbjct: 1 MIEADKKF----LELVKKWGVLSVGLNQKQNTNPVYQYTLEDNPESLTLQDVLESHMTDP 56 Query: 151 LGLDEPSQGEEVNFVPFDKSLNRSQRKAISKALG-SEDFFLVHGPFGTGKTRTLVELIRQ 209 + L+ E+ +PF N QR AI AL + + GP GTGKT TL L+ + Sbjct: 57 IELNSFDSMEKEAGIPFS---NEKQRTAIKMALNENRKLVCIQGPPGTGKTFTLTLLLCR 113 Query: 210 EVKRGNKVLATAESNVAVDNL----VERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQ 265 +++ +V+ A + A+ N+ + L R GIK+ HE L Sbjct: 114 LIQQKKQVVVLAPTREALANIRMMTKKTLKRMGIKV-------------HEHAL------ 154 Query: 266 HELYGELRELRVIGQSLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARG-LSARLIM 324 E RD K R ++ EE+ L RK G ++ ++ Sbjct: 155 --------------MDTNEYRDVINKSD---RALMAAEEVRDL--RKAFDNGEITENVLD 195 Query: 325 EMAEWIKLNRQVQKAFDDARKLEERIARDIIREADVVLTTNSSAALE-VVDYDTYD--VA 381 EM + I +NR + + ++I V T ++ ++ V+ + +D + Sbjct: 196 EMRQSI-INR-----------VRNEVGAEVIGNVRVAFATIGASFVDFVMKHKKFDPCLC 243 Query: 382 IIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIER--- 436 IIDEA Q + K++R V+AGD KQLP + + EA+ L ++ + ++E+ Sbjct: 244 IIDEAAQVMEAQTWPAVYKMKRIVMAGDPKQLPALVFTDEAKAFGLQNSVMDRILEKKNN 303 Query: 437 YPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILN 496 + W ML QYR N +I + + FY ++ D +L ++ Q K N Sbjct: 304 FSWI--MLENQYRSNAKIATWSNTCFYHNQLKTDVKCHEYSLHTILNPQPK-----KFRN 356 Query: 497 PENVIVFIDTSKAENKWER---------------QRRGSESRENPLEAEIVAKIVDKLLS 541 + +V IDTS + +R + + S N EA+I +LL Sbjct: 357 LFDPLVLIDTSLERDVEKRLETYEHAVFDTNSINKTKQGFSYANLAEAKIAIGHYQRLLK 416 Query: 542 IGVKPEWIGVITPYDDQRDLISMKVPE-----------DVEVKTVDGYQGREKEVIILSL 590 GV+P I +ITPY Q L++ + E + TVD QG+E EV+I ++ Sbjct: 417 YGVQPSDIAIITPYKGQTSLVTKLMEEFGAETGYTDFVQTTIGTVDSVQGKEYEVVIFTM 476 Query: 591 VRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTL--SSHETYKKMIEFFK 642 VRSN +GF+ +LRRLNV +TRAKR + +G+ L S + +K+ + FK Sbjct: 477 VRSNPRKTMGFVSELRRLNVVITRAKRHFMFIGNGYLLAESKKDEIRKLYDCFK 530 >dbj|BAB11057.1| (AB015478) contains similarity to nonsense-mediated mRNA decay trans-acting factor~gene_id:MSG15.19 [Arabidopsis thaliana] Length = 676 Score = 135 bits (337), Expect = 1e-30 Identities = 102/340 (30%), Positives = 177/340 (52%), Gaps = 39/340 (11%) Query: 330 IKLNRQVQKAFDDARKLE-ERIARDIIREADVVLTTNSSAA-LEVVDYDTYDVAIIDEAT 387 +K R + K F+ LE E I + ++ AD++L T S AA + V ++ ++DEA Sbjct: 314 LKALRLLPKRFEIPDMLENEDIRKFCLQNADIILCTASGAAEMNVERTGNVELLVVDEAA 373 Query: 388 Q----STIPSILIPLNKVERFVLAGDHKQLPPTILS--LEAQELSRTLFEGLIERYPWKS 441 Q ++ ++ +P + +L GD QLP + + E + R+LFE L+ Sbjct: 374 QLKECESVAALQLP--GLRHAILIGDEFQLPAMVHNEMCEKAKFGRSLFERLV-LLGHNK 430 Query: 442 EMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVI 501 +L VQYRM+ I FP+KEFYGG+I E+V+ + + DS+ Sbjct: 431 HLLDVQYRMHPSISRFPNKEFYGGRIKDAENVKESIYQKRFLKGNMFDSFS--------- 481 Query: 502 VFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEW---IGVITPYDDQ 558 FI+ + + ++ S +N +E ++++I+ L + + +GV++PY Q Sbjct: 482 -FINVGRGKEEFG----DGHSPKNMVEVAVISEIISNLYKVSCERRMKVSVGVVSPYKGQ 536 Query: 559 RDLISMKVPED----------VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRL 608 I K+ + + V++VDG+QG E+++II+S VRSN G++GFL + +R Sbjct: 537 MRAIQEKIGDKYSSLSGQQFTLNVRSVDGFQGGEEDIIIISTVRSNGNGKVGFLNNRQRA 596 Query: 609 NVSLTRAKRKLIVVGDSSTLS-SHETYKKMIEFFKEKGCF 647 NV+LTRA+ L V+G+ +TL+ S + +I + +GCF Sbjct: 597 NVALTRARHCLWVIGNETTLALSGSIWATLISESRTRGCF 636 >gb|AAF57908.1| (AE003804) CG6967 gene product [Drosophila melanogaster] Length = 765 Score = 134 bits (335), Expect = 2e-30 Identities = 139/509 (27%), Positives = 231/509 (45%), Gaps = 103/509 (20%) Query: 172 NRSQRKAISKALG---SEDFFLVHGPFGTGKTRTLVELIRQE--VKRGNKVLATAESNVA 226 N Q +A+ + + ++ +++ GP GTGKT T+VE I Q + +++L TA SN A Sbjct: 252 NAEQLEAVQRIVAGPSTQGPYILFGPPGTGKTTTIVEAILQLRLQQPQSRILVTAGSNSA 311 Query: 227 VDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKR 286 D + +L I R+ +H + L H+L +RV +S+ EK Sbjct: 312 CDTIALKLCEY------IESNIRLQEHFAQQKLPE--PDHQL------IRVYSRSIYEK- 356 Query: 287 DTYTKPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKL 346 G + + L+ K + ++ + Sbjct: 357 ---------------------------GFASVPSLLL--------------KNSNCSKSI 375 Query: 347 EERIARDIIREADVVLTTNSSAALEVVD----YDTYDVAIIDEATQSTIPSILIPLNKVE 402 + I I + +++ T + A V D Y+ + IDEA ST P LI + ++ Sbjct: 376 YDHIKASRIVKYGIIVATLCTVARLVTDTLGRYNFFTHIFIDEAGASTEPEALIGIMGIK 435 Query: 403 R-----FVLAGDHKQLPPTILSLEAQEL--SRTLFEGLIERYPWKSE-----------ML 444 + +L+GDHKQL I S A L SR+L E L++ +KS+ L Sbjct: 436 QTADCHVILSGDHKQLGAVIKSNRAASLGLSRSLMERLLQSDCYKSDENGNYDRNRQMRL 495 Query: 445 VVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFI 504 YR + +I+ ++ +Y G++ A + L +W + NP+ I+F Sbjct: 496 CRNYRSHPQIVRLFNELYYNGELKAQAPAMDVNLAA---------NWSVLTNPQFPIIFQ 546 Query: 505 DTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVK-PEWIGVITPYDDQRDLIS 563 T N+ + S S N LEAE++ V +L++ V E +G++ PY Q L++ Sbjct: 547 ATHGVTNR----EQNSTSSYNNLEAEVICWYVKRLINDRVVGQEDVGIVAPYTAQGKLVT 602 Query: 564 MKVPE----DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKL 619 + +VEV +V+ YQGREK +II SLV+S +GF+ + RR+NV L+RAK L Sbjct: 603 KLLQSKGYPNVEVGSVETYQGREKTIIIASLVKS--FTNMGFMCNPRRVNVLLSRAKALL 660 Query: 620 IVVGDSSTLSSHETYKKMIEFFKEKGCFI 648 I+VG+ TL H +K +I K+ G ++ Sbjct: 661 ILVGNPVTLRHHSDFKFVINECKKHGTYL 689 >gi|6321958 DNA replication helicase; Dna2p [Saccharomyces cerevisiae] >gi|731738|sp|P38859|DNA2_YEAST DNA REPLICATION HELICASE DNA2 >gi|626832|pir||S48904 probable purine nucleotide-binding protein YHR164c - yeast (Saccharomyces cerevisiae) >gi|458906|gb|AAB68010.1| (U00027) Dna2p: DNA replication helicase [Saccharomyces cerevisiae] Length = 1522 Score = 134 bits (334), Expect = 3e-30 Identities = 99/309 (32%), Positives = 163/309 (52%), Gaps = 21/309 (6%) Query: 355 IREADVVLTT--NSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQ 412 I VV TT + L ++ +D I+DEA+Q ++P L PL RF++ GDH Q Sbjct: 1155 INSTSVVATTCLGINDILFTLNEKDFDYVILDEASQISMPVALGPLRYGNRFIMVGDHYQ 1214 Query: 413 LPPTILSLEAQ--ELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKI--- 467 LPP + + A+ L +LF+ E++P L +QYRM I+ + Y K+ Sbjct: 1215 LPPLVKNDAARLGGLEESLFKTFCEKHPESVAELTLQYRMCGDIVTLSNFLIYDNKLKCG 1274 Query: 468 ---IADESVRGITLRDLVEYQSPNDS---WGK-ILNPENVIVFIDTSKAENKWERQRRGS 520 + +S+ L Y++ + + W + IL P +VF++ + E+ + Sbjct: 1275 NNEVFAQSLELPMPEALSRYRNESANSKQWLEDILEPTRKVVFLNYDNCPDIIEQSEK-- 1332 Query: 521 ESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQ----RDLISMKVPEDVEVKTVD 576 ++ N EAE+ + V+ +L GV E IGV+T Y Q + + + V + +E+ T D Sbjct: 1333 DNITNHGEAELTLQCVEGMLLSGVPCEDIGVMTLYRAQLRLLKKIFNKNVYDGLEILTAD 1392 Query: 577 GYQGREKEVIILSLVRSN-KLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYK 635 +QGR+K+ II+S+VR N +L LK+LRR+NV++TRAK KLI++G ST+ S K Sbjct: 1393 QFQGRDKKCIIISMVRRNSQLNGGALLKELRRVNVAMTRAKSKLIIIGSKSTIGSVPEIK 1452 Query: 636 KMIEFFKEK 644 + +E+ Sbjct: 1453 SFVNLLEER 1461 >dbj|BAB11372.1| (AB017068) contains similarity to nonsense-mediated mRNA decay trans-acting factors~gene_id:MJG14.22 [Arabidopsis thaliana] Length = 880 Score = 131 bits (327), Expect = 2e-29 Identities = 102/351 (29%), Positives = 177/351 (50%), Gaps = 48/351 (13%) Query: 330 IKLNRQVQKAFDDARKLE-ERIARDIIREADVVLTTNSSAA-LEVVDYDTYDVAIIDEAT 387 +K R + K F+ LE E I + ++ AD++L T S AA + V ++ ++DEA Sbjct: 509 LKALRLLPKRFEIPDMLENEDIRKFCLQNADIILCTASGAAEMNVERTGNVELLVVDEAA 568 Query: 388 Q----STIPSILIPLNKVERFVLAGDHKQLPPTILS-----------LEAQELSRTLFEG 432 Q ++ ++ +P + +L GD QLP + + E + R+LFE Sbjct: 569 QLKECESVAALQLP--GLRHAILIGDEFQLPAMVHNEYCNMGIMWQMCEKAKFGRSLFER 626 Query: 433 LIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWG 492 L+ +L VQYRM+ I FP+KEFYGG+I E+V+ + + S+ Sbjct: 627 LV-LLGHNKHLLDVQYRMHPSISRFPNKEFYGGRIKDAENVKESIYQKRFLQGNMFGSFS 685 Query: 493 KILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEW---I 549 FI+ + + ++ S +N +E +V++I+ L + + + Sbjct: 686 ----------FINVGRGKEEFG----DGHSPKNMVEVAVVSEIISNLFKVSCERRMKVSV 731 Query: 550 GVITPYDDQRDLISMKVPED----------VEVKTVDGYQGREKEVIILSLVRSNKLGEI 599 GV++PY Q I K+ + + V++VDG+QG E+++II+S VRSN G++ Sbjct: 732 GVVSPYKGQMRAIQEKIGDKYSSLSGQQFTLNVRSVDGFQGGEEDIIIISTVRSNSNGKV 791 Query: 600 GFLKDLRRLNVSLTRAKRKLIVVGDSSTLS-SHETYKKMIEFFKEKGCFIE 649 GFL + +R NV+LTRA+ L V+G+ +TL+ S + +I + +GCF + Sbjct: 792 GFLNNRQRANVALTRARHCLWVIGNETTLALSGSIWATLISESRTRGCFYD 842 >gb|AAB67523.1| (U21094) Sen1p [Saccharomyces cerevisiae] Length = 757 Score = 131 bits (326), Expect = 3e-29 Identities = 112/366 (30%), Positives = 182/366 (49%), Gaps = 39/366 (10%) Query: 300 LSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERIAR-DIIREA 358 +S E+I KL + R +++I E+ R+ R L+ R A+ I+ + Sbjct: 33 MSTEDISKLQLKIREL----SKIINELGRDRDEMREKNSVNYRNRDLDRRNAQAHILAVS 88 Query: 359 DVVLTTNSSAALEVVDYD--TYDVAIIDEATQSTIPSILIPLNKV-ERFVLAGDHKQLPP 415 D++ +T S +A +V+ +D IIDEA Q T S +IPL +R ++ GD QLPP Sbjct: 89 DIICSTLSGSAHDVLATMGIKFDTVIIDEACQCTELSSIIPLRYGGKRCIMVGDPNQLPP 148 Query: 416 TILSLEAQELSRTLFEGLIERYPWKSE--MLVVQYRMNERIMEFPSKEFYGGKIIADESV 473 T+LS A + L R S +L VQYRM+ I +FPS EFY G++ + Sbjct: 149 TVLSGAASNFKYN--QSLFVRMEKNSSPYLLDVQYRMHPSISKFPSSEFYQGRLKDGPGM 206 Query: 474 RGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVA 533 + R W + L P F D + Q + S N E + Sbjct: 207 DILNKRP----------WHQ-LEPLAPYKFFDIISGR---QEQNAKTMSYTNMEEIRVAI 252 Query: 534 KIVDKLL-SIGVKPEW---IGVITPYDDQRDLISMK--------VPEDVEVKTVDGYQGR 581 ++VD L K ++ IG+I+PY +Q + + + + ++ T+DG+QG+ Sbjct: 253 ELVDYLFRKFDNKIDFTGKIGIISPYREQMQKMRKEFARYFGGMINKSIDFNTIDGFQGQ 312 Query: 582 EKEVIILSLVRSNKL-GEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEF 640 EKE+I++S VR++ +GFLKD RR+NV+LTRAK + V+G +L+ + ++ +IE Sbjct: 313 EKEIILISCVRADDTKSSVGFLKDFRRMNVALTRAKTSIWVLGHQRSLAKSKLWRDLIED 372 Query: 641 FKEKGC 646 K++ C Sbjct: 373 AKDRSC 378 >pir||T22132 hypothetical protein F43G6.1a - Caenorhabditis elegans >gi|3877086|emb|CAA90399.1| (Z50070) similar to DNA binding protein~cDNA EST EMBL:Z14942 comes from this gene~cDNA EST yk46a12.3 comes from this gene~cDNA EST yk27h9.5 comes from this gene~cDNA EST yk46a12.5 comes from this gene~cDNA EST yk130a10.5 comes from this gene~cDNA EST y> Length = 1105 Score = 131 bits (326), Expect = 3e-29 Identities = 100/285 (35%), Positives = 154/285 (53%), Gaps = 13/285 (4%) Query: 352 RDIIREADVVLTTNSSAALEVV-DYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDH 410 R +++ +V T E++ Y +DV I+DEA+ P +L L +FVL GD Sbjct: 793 RKVMKTTPIVACTCHHVPRELLFSYRHFDVVIVDEASMVLEPLLLPVLATSNKFVLVGDC 852 Query: 411 KQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKII 468 KQL P ++S +A++ + E L + +P L QYRMN I SK FY ++I Sbjct: 853 KQLTPLVVSRKAKQEGAGISTMEKLQQSHPGVVVSLTSQYRMNREISVLSSKLFYENRLI 912 Query: 469 -ADESVRGITLRDLVEY----QSPNDSWGKILNPE--NVIVFIDT-SKAENKWERQRRGS 520 +ESV +L +Y +D K L+ + + VF+DT S +K + + Sbjct: 913 CGNESVSRSSLDRTGDYIVAMDDGSDHIRKALSGDIKDSCVFLDTQSTINSKMQCEDGEG 972 Query: 521 ESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLI-SMKVPEDVEVKTVDGYQ 579 N EA++++++ + + GVKP IGV++ Y Q D I + +++EV T+D YQ Sbjct: 973 GGMCNDGEAKLISELCQQFVMSGVKPHEIGVMSAYRRQVDHIRGILNSDELEVNTIDSYQ 1032 Query: 580 GREKEVIILSLV-RSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVG 623 GREK VII SL +N + LKD RR+NV+LTRA++KL+VVG Sbjct: 1033 GREKRVIIWSLTWTNNSTKKSELLKDERRVNVALTRARQKLVVVG 1077 >pir||T22138 hypothetical protein F43G6.1b - Caenorhabditis elegans >gi|5824500|emb|CAB54253.1| (Z50070) cDNA EST yk592a5.5 comes from this gene~cDNA EST yk653b11.5 comes from this gene [Caenorhabditis elegans] Length = 1069 Score = 131 bits (326), Expect = 3e-29 Identities = 100/285 (35%), Positives = 154/285 (53%), Gaps = 13/285 (4%) Query: 352 RDIIREADVVLTTNSSAALEVV-DYDTYDVAIIDEATQSTIPSILIPLNKVERFVLAGDH 410 R +++ +V T E++ Y +DV I+DEA+ P +L L +FVL GD Sbjct: 757 RKVMKTTPIVACTCHHVPRELLFSYRHFDVVIVDEASMVLEPLLLPVLATSNKFVLVGDC 816 Query: 411 KQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKII 468 KQL P ++S +A++ + E L + +P L QYRMN I SK FY ++I Sbjct: 817 KQLTPLVVSRKAKQEGAGISTMEKLQQSHPGVVVSLTSQYRMNREISVLSSKLFYENRLI 876 Query: 469 -ADESVRGITLRDLVEY----QSPNDSWGKILNPE--NVIVFIDT-SKAENKWERQRRGS 520 +ESV +L +Y +D K L+ + + VF+DT S +K + + Sbjct: 877 CGNESVSRSSLDRTGDYIVAMDDGSDHIRKALSGDIKDSCVFLDTQSTINSKMQCEDGEG 936 Query: 521 ESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLI-SMKVPEDVEVKTVDGYQ 579 N EA++++++ + + GVKP IGV++ Y Q D I + +++EV T+D YQ Sbjct: 937 GGMCNDGEAKLISELCQQFVMSGVKPHEIGVMSAYRRQVDHIRGILNSDELEVNTIDSYQ 996 Query: 580 GREKEVIILSLV-RSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVG 623 GREK VII SL +N + LKD RR+NV+LTRA++KL+VVG Sbjct: 997 GREKRVIIWSLTWTNNSTKKSELLKDERRVNVALTRARQKLVVVG 1041 >gi|11499542 DNA helicase, putative [Archaeoglobus fulgidus] >gi|7483284|pir||G69494 DNA helicase homolog - Archaeoglobus fulgidus >gi|2648582|gb|AAB89295.1| (AE000968) DNA helicase, putative [Archaeoglobus fulgidus] Length = 453 Score = 130 bits (324), Expect = 4e-29 Identities = 109/306 (35%), Positives = 156/306 (50%), Gaps = 30/306 (9%) Query: 349 RIARDIIREADVVLTTN----SSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVERF 404 RI D+IR+ +V+ + +AL+ D+DT IIDEA+ + I + L+ L K E+ Sbjct: 164 RIQNDMIRKGKIVVGSTILKGMMSALKNYDFDT---VIIDEASNTCISTALLALEKAEKA 220 Query: 405 VLAGDHKQLPPTILSLEAQELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYG 464 V+ GD QLPP + + + LI Y K+ L YR N +I EF ++ YG Sbjct: 221 VVVGDPYQLPPVYEVGGHKAAKFSAYNFLINIY-GKNLWLRRHYRSNAKIAEFAARHVYG 279 Query: 465 GKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRE 524 I DE R I + + + ++ +PE +VFID + E RR S+ Sbjct: 280 FLEI-DEKCRRIKI------EPCKTTIPEVGDPEKPLVFIDCNGVE------RREGRSKV 326 Query: 525 NPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE---DVEVKTVDGYQGR 581 N EAE+VA I ++L V E +GVITPY Q +LI + E VEV TV YQGR Sbjct: 327 NEEEAEVVAMIAEELAEC-VGEENVGVITPYVKQAELIRGILSEFGVMVEVSTVHSYQGR 385 Query: 582 EKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETY--KKMIE 639 EK+V+I S+ + G F + R NV+LTRA++K I VG+S L + M+ Sbjct: 386 EKDVVIYSITAT---GNPYFASEKRLFNVALTRARKKFIAVGNSKALEGKNLLLTRFMVA 442 Query: 640 FFKEKG 645 KE G Sbjct: 443 AIKEGG 448 >dbj|BAB11370.1| (AB017068) contains similarity to nonsense-mediated mRNA decay trans-acting factors~gene_id:MJG14.20 [Arabidopsis thaliana] Length = 701 Score = 127 bits (316), Expect = 4e-28 Identities = 98/339 (28%), Positives = 174/339 (50%), Gaps = 34/339 (10%) Query: 330 IKLNRQVQKAFDDARKLEERIARDI-IREADVVLTTNSSAA-LEVVDYDTYDVAIIDEAT 387 +++ R + + F+ + LE + ++ AD++ T S AA + + + D+ ++DEA Sbjct: 340 LQILRLLPERFEVSDMLENNDTKTFCLQNADIIFCTASGAADMNPIRTGSVDLLVVDEAA 399 Query: 388 Q-STIPSIL-IPLNKVERFVLAGDHKQLPPTILS--LEAQELSRTLFEGLIERYPWKSEM 443 Q S+ + L+ + VL GD QLP + + E + R+LFE L+ + Sbjct: 400 QLKECESVAALQLSGLRHAVLIGDELQLPAMVHNEICEKAKFGRSLFERLV-LLGHNKHL 458 Query: 444 LVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVF 503 L VQYRM+ I FP+KEFYGG+I +V+ + + S+ F Sbjct: 459 LNVQYRMHPSISRFPNKEFYGGRIKDAANVQESIYQKRFLQGNMFGSFS----------F 508 Query: 504 IDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEW---IGVITPYDDQRD 560 I+ + E ++ S +N +E ++++I+ L + + +GV++PY Q Sbjct: 509 INVGRGEEEFG----DGHSPKNMVEVAVISEIISNLFKVSSERRIKMSVGVVSPYKGQVR 564 Query: 561 LISMKVPED---------VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVS 611 I + + V++VDG+QG E+++II+S VRSN G++GFL + +R NV+ Sbjct: 565 AIQERTTNKYSSLSGLFTLNVRSVDGFQGGEEDIIIISTVRSNGNGKVGFLNNRQRANVA 624 Query: 612 LTRAKRKLIVVGDSSTLS-SHETYKKMIEFFKEKGCFIE 649 LTRA+ L V+G+ +TL+ S ++ K+I + GCF + Sbjct: 625 LTRARHCLWVIGNETTLALSGSSWAKLISESRTLGCFYD 663 >pir||T00740 hypothetical protein F22O13.35 - Arabidopsis thaliana Length = 814 Score = 125 bits (312), Expect = 1e-27 Identities = 90/258 (34%), Positives = 127/258 (48%), Gaps = 49/258 (18%) Query: 378 YDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIE 435 +DV IIDEA Q +P + PL FVL GDH QLPP + S EA+E + +LF L E Sbjct: 550 FDVCIIDEAGQIALPVSIGPLLFASTFVLVGDHYQLPPLVQSTEARENGMGISLFRRLSE 609 Query: 436 RYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKIL 495 +P +L QYRM IME + YG ++ + Sbjct: 610 AHPQAISVLQNQYRMCRGIMELSNALIYGDRLCCGSA----------------------- 646 Query: 496 NPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPY 555 + + + TS + + W + KIV++L++ GV + IG+ITPY Sbjct: 647 EVADATLVLSTSSSTSPW------------------LKKIVEELVNNGVDSKDIGIITPY 688 Query: 556 DDQRDLISMKVP-EDVEVKTVDGYQGREKEVIILSLVRSN---KLGEIGFLKDLRRLNVS 611 + Q LI +P VE+ T+D YQGR+K+ I++S VRS + L D R+NV+ Sbjct: 689 NSQASLIQHAIPTTPVEIHTIDKYQGRDKDCILVSFVRSREKPRSSASSLLGDWHRINVA 748 Query: 612 LTRAKRKLIVVGDSSTLS 629 LTRA KLI+VG TLS Sbjct: 749 LTRA--KLIMVGSQRTLS 764 Score = 77.6 bits (188), Expect = 4e-13 Identities = 41/127 (32%), Positives = 77/127 (60%), Gaps = 2/127 (1%) Query: 157 SQGEEVNFVPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNK 216 SQ ++++ +KSLN QR+AI K L ++D+ L+ G GTGKT T+V ++ + RG+ Sbjct: 410 SQDPAISYIWSEKSLNNDQRQAILKILTAKDYALILGMPGTGKTSTMVHAVKALLIRGSS 469 Query: 217 VLATAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKHLHETTLA--YLITQHELYGELRE 274 +L + +N AVDNL+ +L GI+ +RIG V + + E+ + + + ++ +L + Sbjct: 470 ILLASYTNSAVDNLLIKLKAQGIEFLRIGRDEAVHEEVRESCFSAMNMCSVEDIKKKLDQ 529 Query: 275 LRVIGQS 281 ++V+ + Sbjct: 530 VKVVAST 536 >dbj|BAB08973.1| (AB024026) gb|AAD48967.1~gene_id:K15O15.6~strong similarity to unknown protein [Arabidopsis thaliana] Length = 536 Score = 122 bits (304), Expect = 1e-26 Identities = 94/305 (30%), Positives = 158/305 (50%), Gaps = 39/305 (12%) Query: 367 SAALEVVDYDT--YDVAIIDEATQ----STIPSILIPLNKVERFVLAGDHKQLPPTILS- 419 S A E+ + T +V ++DEA Q ++ ++ +P + +L GD QLP + + Sbjct: 233 SGAAEINEERTGNIEVLVVDEAAQLKECESVAALQLP--GLRHAILIGDEFQLPAMVHND 290 Query: 420 -LEAQELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITL 478 E + R+LFE L+ K +L VQYRM+ I FP KEFYGG+I +V+ Sbjct: 291 QCEKAKFGRSLFERLV-LLGHKKHLLDVQYRMHPSISRFPYKEFYGGRIKDAANVQESIY 349 Query: 479 RDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDK 538 + + S+ FI+ + + ++ +S +N +E +V++I+ Sbjct: 350 QKRFLQGNMFGSFS----------FINVGRGKEEFG----DGDSPKNMVEVAVVSEIISN 395 Query: 539 LLSIGVKPEW---IGVITPYDDQRDLISMKVPED----------VEVKTVDGYQGREKEV 585 L + + + +GVITPY Q I ++ + V V++VDG+QG E+++ Sbjct: 396 LFKVSRERKMKMSVGVITPYKGQVRAIQERIRDKYSSLSGELFTVNVRSVDGFQGGEEDI 455 Query: 586 IILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLS-SHETYKKMIEFFKEK 644 II+S VRSN G++GFL + +R NV+LTRA+ L V+G+ STL+ S + +I K + Sbjct: 456 IIISTVRSNSNGKVGFLSNRQRANVALTRARHCLWVIGNESTLARSGSIWANLISDSKRR 515 Query: 645 GCFIE 649 CF + Sbjct: 516 KCFYD 520 >dbj|BAB11373.1| (AB017068) contains similarity to DNA helicase~gene_id:MJG14.23 [Arabidopsis thaliana] Length = 834 Score = 122 bits (303), Expect = 1e-26 Identities = 95/324 (29%), Positives = 164/324 (50%), Gaps = 39/324 (12%) Query: 348 ERIARDIIREADVVLTTNSSAA-LEVVDYDTYDVAIIDEATQ----STIPSILIPLNKVE 402 E I + ++ AD++ T SS A + + D+ ++DE Q ++ ++ +P + Sbjct: 492 EDIRKFCLQNADIIFCTASSVANINPARIGSVDLLVVDETAQLKECESVAALQLP--GLC 549 Query: 403 RFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSK 460 +L GD QLP + + E + R+LFE L+ +L VQYRM+ I FP+K Sbjct: 550 HALLIGDEYQLPAMVHNEECDKAKFGRSLFERLV-LIGHSKHLLNVQYRMHPSISRFPNK 608 Query: 461 EFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGS 520 EFYGG+I +V+ +S + N FI+ + + ++ Sbjct: 609 EFYGGRITDAANVQ----------ESIYEKRFLQGNMFGTFSFINVGRGKEEFG----DG 654 Query: 521 ESRENPLEAEIVAKIVDKLLSIGVKPEW---IGVITPYDDQRDLISMKVPED-------- 569 S +N +E +++KI+ L + + + +GVI+PY Q I +V + Sbjct: 655 HSPKNMVEVAVISKIISNLFKVSSQRKQKMSVGVISPYKGQVRAIQERVGDKYNSLSVDQ 714 Query: 570 ---VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSS 626 + V++VDG+QG E +VII+S VR N G +GFL + +R NV+LTRA+ L V+G+ + Sbjct: 715 LFTLNVQSVDGFQGGEVDVIIISTVRCNVNGNVGFLSNRQRANVALTRARHCLWVIGNGT 774 Query: 627 TLS-SHETYKKMIEFFKEKGCFIE 649 TL+ S + ++I + +GCF + Sbjct: 775 TLALSGSIWAELISESRTRGCFYD 798 >gb|AAD48967.1|AF147263_9 (AF147263) contains similarity to nonsense-mediated mRNA decay trans-acting factors [Arabidopsis thaliana] >gi|7267314|emb|CAB81096.1| (AL161503) contains similarity to nonsense-mediated mRNA decay trans-acting factors~similarity to~Contains Prokaryotic membrane lipoprotein lipid attachment site AA120-130 [Arabidopsis thaliana] Length = 660 Score = 122 bits (302), Expect = 2e-26 Identities = 101/315 (32%), Positives = 160/315 (50%), Gaps = 34/315 (10%) Query: 334 RQVQKAFD-DARKLEERIARDIIREADVVLTTNSSAALEVVDY-DTYDVAIIDEATQ-ST 390 R + K F+ A ++E I ++ A ++ T S AA + + D+ ++DEA Q Sbjct: 356 RLLSKRFEIPALLMKEDIRTFCLQNAHIIFCTASGAAEMTAERAGSIDMLVVDEAAQLKE 415 Query: 391 IPSIL-IPLNKVERFVLAGDHKQLPPTILS--LEAQELSRTLFEGLIERYPWKSEMLVVQ 447 S+ + L + VL GD QLP + S E + R+LFE L + K +L VQ Sbjct: 416 CESVAALQLQGLHHAVLIGDELQLPAMVQSEVCEKAKFVRSLFERL-DSLGHKKHLLNVQ 474 Query: 448 YRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTS 507 YRM+ I FP+ EFYGGKI E V+ T + + S+ FI+ Sbjct: 475 YRMHPSISLFPNMEFYGGKISDAEIVKESTYQKRFLQGNMFGSFS----------FINVG 524 Query: 508 KAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEW---IGVITPYDDQRDLISM 564 + ++ S +N +E +V++I+ LL + + + +GVI+PY Q I Sbjct: 525 LGKEEFG----DGHSPKNMVEIAVVSEILTNLLKVSSETKTKMSVGVISPYKAQVSAIQE 580 Query: 565 KVPED----------VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTR 614 ++ + + V++VDG+QG E+++II+S VRSN G IGFL + +R NV+LTR Sbjct: 581 RIGDKYTSVSDNLFTLNVRSVDGFQGGEEDIIIISTVRSNCNGNIGFLSNRQRANVALTR 640 Query: 615 AKRKLIVVGDSSTLS 629 A+ L V+G+ TLS Sbjct: 641 ARHCLWVIGNERTLS 655 >gb|AAF23836.1|AC007234_8 (AC007234) F1E22.16 [Arabidopsis thaliana] Length = 1075 Score = 122 bits (302), Expect = 2e-26 Identities = 103/326 (31%), Positives = 161/326 (48%), Gaps = 58/326 (17%) Query: 363 TTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNK--VERFVLAGDHKQLPPTILS- 419 T +SSA L + + +IDEA Q IPL ++ +L GD KQLP I S Sbjct: 540 TASSSARLHMSS--PIQLLVIDEAAQLKECESAIPLQLRGLQHAILIGDEKQLPAMIKSN 597 Query: 420 --------------------------LEAQELSRTLFEGLIERYPWKSEMLVVQYRMNER 453 +L R+LFE L+ ++L +QYRM+ Sbjct: 598 VGSLILTNYTHIHSLLFAYLISYVQIASEADLGRSLFERLV-LLGHNKQLLNMQYRMHPS 656 Query: 454 IMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKW 513 I FP++EFY KI+ SVR LR + P +G FI+ + ++ Sbjct: 657 ISIFPNREFYDMKILDAPSVR---LRSYEKKFLPEKMYGP-------YSFINIAYGREQF 706 Query: 514 ERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPE---WIGVITPYDDQRDLISMKVPE-- 568 S +N +E +VA+IV KL S+ K +GVI+PY Q I ++ E Sbjct: 707 GE----GYSSKNLVEVSVVAEIVSKLYSVSRKTGRTISVGVISPYKAQVFAIQERIGEKY 762 Query: 569 ------DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVV 622 V V++VDG+QG E+++II+S VRSN G IGFL + +R NV+LTRA+ L ++ Sbjct: 763 NTEGTFTVSVRSVDGFQGGEEDIIIISTVRSNGNGAIGFLSNQQRTNVALTRARYCLWIL 822 Query: 623 GDSSTLSSHET-YKKMIEFFKEKGCF 647 G+ +TL+++ + ++++++ K + CF Sbjct: 823 GNEATLTNNRSVWRQLVDDAKARNCF 848 >gb|AAF46543.1| (AE003449) CG2990 gene product [Drosophila melanogaster] Length = 1119 Score = 120 bits (299), Expect = 4e-26 Identities = 98/313 (31%), Positives = 153/313 (48%), Gaps = 50/313 (15%) Query: 378 YDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIE 435 +D I+DEATQ P++L PL +FVL GD +QLPP + S EA++ TLF+ L Sbjct: 784 FDYCIVDEATQVLQPTVLRPLIHCSKFVLVGDPEQLPPIVRSKEARQRGADETLFQRLDS 843 Query: 436 RYPWKSEMLVVQYRMNERIMEFPSKEFYGGKI-IADESVRGITLRDLVEYQSPNDSWGK- 493 + +L +QYRMN+ I ++ YGG + A + V G VE + W + Sbjct: 844 EKA--TAVLSLQYRMNKTITRLANELTYGGDLKCASDEVSGARFE--VELLNEAPRWVQR 899 Query: 494 --ILNPENVIVFIDT--------------------------SKAENKWERQRRGSESR-- 523 + E + I+T S +E+K E ++ S+ R Sbjct: 900 ALTTHLEQAVTLINTGDCLERCQEFVYASQRLVDTCSSIEQSFSEDKDEIRKLTSKKRVS 959 Query: 524 --ENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDL---ISMKVPEDVEVKTVDGY 578 N EA IV ++ LL G + IGVI PY Q +L ++ K+ D+E TVD + Sbjct: 960 KYTNYCEAGIVMHLLRYLLKSGYEASRIGVIAPYRAQVELFKKLASKLDTDLECNTVDQF 1019 Query: 579 QGREKEVIILSLVRSN-------KLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSH 631 QGR+K +II S ++ + E L+D RRL V++TRAK KLI++GD L + Sbjct: 1020 QGRDKNLIIYSCSKTGGDFSDMERSREAEILEDQRRLTVAITRAKNKLILLGDIKCLEQY 1079 Query: 632 ETYKKMIEFFKEK 644 ++++ + ++ Sbjct: 1080 GPFRQLFKHIPDR 1092 Score = 71.0 bits (171), Expect = 4e-11 Identities = 78/270 (28%), Positives = 123/270 (44%), Gaps = 28/270 (10%) Query: 36 ERERLGRAILNLNGKIIGEELGYFLVKYGRNREIKTE-----------ISVGDLVVISKR 84 ERE+ G AI +L + G+E+ +Y + E+ E +G+ VVIS Sbjct: 501 EREKEGIAIRHLK-LVKGQEVILEEGRYRQTLELGEEADPSRDLSLSGFDLGEYVVISST 559 Query: 85 DPLKSDLLGTVVEKGKRFIVVALET--VPEWALRDVRIDLYANDITFRRWLENLNTIKKA 142 L + G +V R + + LE ++ ID + + NL + Sbjct: 560 SRL-AVAAGFIVSIEARRLDLRLERDLSQRYSEETFIIDKHDSQSFATFNFTNLGMLLSE 618 Query: 143 GKR--ALRFYLGLDEPSQGEEV-------NFVPFDKSLNRSQRKAISKALGSEDFFLVHG 193 G+R LR + +P + +V P +LN+ Q+ A +AL + L+ G Sbjct: 619 GERFQELRDIIVAKKPPEQHKVLPKIILTKGAPILLNLNKVQQNAALRALTTSSHLLIKG 678 Query: 194 PFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNLVERLSRSGIKIVRIGHPSRVSKH 253 GTGKT+TLV L+R G VL TA+++ AVDNL+ RL G+ ++R+G SR+ K Sbjct: 679 LPGTGKTQTLVALVRLLHLLGKSVLITAQTHSAVDNLIMRLLPFGLPMMRLGSGSRIHKQ 738 Query: 254 LHETTLAYLI----TQHELYGELRELRVIG 279 L E + L T EL L + ++G Sbjct: 739 LEEISEERLTKDCKTVEELEKALGQPSIVG 768 >gb|AAF56255.1| (AE003746) CG6204 gene product [Drosophila melanogaster] Length = 903 Score = 115 bits (284), Expect = 2e-24 Identities = 134/492 (27%), Positives = 227/492 (45%), Gaps = 75/492 (15%) Query: 165 VPFDKSLNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNK-----VLA 219 +P D LN SQ+ A +AL E F ++ GP GTGKT V+L+ ++ ++ Sbjct: 444 LPEDLHLNESQKTAFKEALCRE-FSIIQGPPGTGKTHLSVQLVNSLIQNAKALGTGPIIV 502 Query: 220 TAESNVAVDNLVERLSRSGIKIVRIGHPSR---VSKHLHETTLAYLITQHELYGELRELR 276 +N ++D + ++SR +I+R G+ SR +SK TT+ + L R Sbjct: 503 LTYTNNSLDKFLVKISRYTQEILRFGNQSRDPQISKFNLSTTIKPELVPPRLK------R 556 Query: 277 VIGQSLAEKRDTYTKPTPKFRRGLSDEEIIK--LAERKRGARGLSARLIMEMAEWIKLNR 334 + E ++ + + EE + LA +++ + ++AE I+ R Sbjct: 557 IWWLVNCEYKEKFRNLQGLYANFDGSEESYQDTLAAQEK---------LNQVAERIETLR 607 Query: 335 QVQKAFDDARKLEERIARDIIREADVVLTTNSSAALEVVDYDTYD--VAIIDEATQSTIP 392 V + F + RE D++ T + AA + + +EA + Sbjct: 608 MVFQFF-------------LAREKDLLAMTTTCAARHNFLFRLLQSKCVLFEEAAEIQEA 654 Query: 393 SILIPLNK-VERFVLAGDHKQLPPTILSLEAQELSRTLFEGLIER-YPWKSEMLVVQYRM 450 I+ L E +L GDHKQL P S + ++S LFE LI P+ L +QYRM Sbjct: 655 HIVACLTPHTEHVILVGDHKQLQPFSGSRKVPQIS--LFERLIVAGLPFSR--LNLQYRM 710 Query: 451 NERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAE 510 I E Y +++ ESV+ EY+ L +N + F+ ++ E Sbjct: 711 RSCISELLVPSIYD-ELLCSESVK--------EYEDIR------LMSKN-LYFVQHNQPE 754 Query: 511 NKWERQRRGSESRENPLEAEIVAKIVDKLLSIG-VKPEWIGVITPYDDQRDLISMKVPED 569 + G N EA ++AK+ + L+ K I +++PY+ Q + I +P++ Sbjct: 755 HCMSDMSIG-----NLYEAGVLAKLTEFLIQKAQYKHSDIVILSPYNGQIECIKNALPQN 809 Query: 570 ----VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDS 625 V+V +VD +QG E +++LSLVRSN G IGFL+ R+ V+L+RA+ L +VG+ Sbjct: 810 YRSTVQVASVDSFQGLEANIVLLSLVRSNISGRIGFLRQANRVCVALSRARWALYIVGNV 869 Query: 626 STLSSHETYKKM 637 + L +T+ K+ Sbjct: 870 TILK--DTFPKI 879 >gb|AAA58611.1| (M64979) glial factor-1 [Homo sapiens] Length = 376 Score = 115 bits (284), Expect = 2e-24 Identities = 56/136 (41%), Positives = 91/136 (66%), Gaps = 3/136 (2%) Query: 513 WERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE---D 569 +E + +S+ NP E +V+ + L+ GV I V++PY+ Q DL+ + + Sbjct: 9 FELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRHPE 68 Query: 570 VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLS 629 +E+K+VDG+QGREKE +ILS VRSN+ GE+GFL + RR+NV++TRA+R + V+ DS T++ Sbjct: 69 LEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTVN 128 Query: 630 SHETYKKMIEFFKEKG 645 +H K ++E+F + G Sbjct: 129 NHAFLKTLVEYFTQHG 144 >pir||A70369 hypothetical protein aq_791 - Aquifex aeolicus >gi|2983352|gb|AAC06940.1| (AE000707) putative protein [Aquifex aeolicus] Length = 163 Score = 112 bits (278), Expect = 1e-23 Identities = 65/138 (47%), Positives = 92/138 (66%), Gaps = 4/138 (2%) Query: 8 NRLKELVEIEREAEIEAMRLEMRRLSGIERERLGRAILNLNGKIIGEEL-GYFLVKYGRN 66 N K L+++ER A+ E E++ LSG ERE+ GRAILNL K +G L G +LV+Y R Sbjct: 14 NYFKRLIDLERRAQTELHLKEIKTLSGKEREKRGRAILNLRAKFLGRGLGGVYLVRYSRP 73 Query: 67 REI-KTEISVGDLVVISKRDPLKSDLLGTVVEKGKRFIVVAL-ETVPEWAL-RDVRIDLY 123 + + KTEIS GD+V++SK P ++ GTV EK ++VVA + P +AL +DVRIDL+ Sbjct: 74 QGLPKTEISTGDIVLVSKGKPTVKEVQGTVAEKTNYYLVVAFRDKPPPYALGKDVRIDLF 133 Query: 124 ANDITFRRWLENLNTIKK 141 +N+ITF+R E L K+ Sbjct: 134 SNEITFKRMEEALKNFKE 151 >pir||D64588 probable DNA helicase - Helicobacter pylori (strain 26695) Length = 274 Score = 109 bits (270), Expect = 9e-23 Identities = 76/284 (26%), Positives = 147/284 (51%), Gaps = 44/284 (15%) Query: 378 YDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTI----------------LSLE 421 +DV IIDE ++T P ILIP + ++ +L GDH QLPP+I +++ Sbjct: 3 FDVTIIDETGRATAPEILIPALRTKKLILIGDHNQLPPSIDRYLLEQLESDDIQNLDAID 62 Query: 422 AQELSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDL 481 Q L + FE L + P ++ ++ ++RM I S+ FY E ++ +++ Sbjct: 63 RQLLEESFFENLYKYIPESNKAMLNEFRMPASIGSLVSQLFY------KEKLKNGVIKNT 116 Query: 482 VEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLS 541 ++ +P+N+I +I+ E + + ++ S ++ + + + ++++L+ Sbjct: 117 SQF----------YDPKNIIRWIN---VEGEHQLEKTSSYNKNQVQKIIELLEQINRVLN 163 Query: 542 IGVKPEWIGVITPYDDQRDLISMKVP-------EDVEVKTVDGYQGREKEVIILSLVRSN 594 + IG+ITPY+ Q+ + +V +++++ TVD +QG + ++II S V++ Sbjct: 164 QRKIRKTIGIITPYNAQKRCLRSEVEKYGFKNFDELKIDTVDAFQGEKADIIIYSTVKT- 222 Query: 595 KLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMI 638 G + FL D +RLNV+++RAK LI VG S + + +K I Sbjct: 223 -YGNLSFLIDSKRLNVAISRAKENLIFVGKKSFFENLRSDEKNI 265 >pir||T41111 hypothetical ATP binding protein - fission yeast (Schizosaccharomyces pombe) >gi|3581879|emb|CAA20777.1| (AL031540) hypothetical protein [Schizosaccharomyces pombe] Length = 1015 Score = 101 bits (250), Expect = 2e-20 Identities = 84/291 (28%), Positives = 146/291 (49%), Gaps = 38/291 (13%) Query: 354 IIREADVV--LTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIP--LNKVERFVLAGD 409 ++R A+V+ TT + ++++ + I+EA + +IP +E+ VL GD Sbjct: 679 LLRGANVIGMTTTGLNKYRDILERINPKICFIEEAAD-VLEGPIIPAVFPSLEQLVLIGD 737 Query: 410 HKQLPPTILSLEAQE----LSRTLFEGLIERYPWKSEMLVVQYRMNERIMEFPSKEFYGG 465 HKQL P + ++ LS ++FE L+E + L +Q RM+ +I S + Sbjct: 738 HKQLRPGCSTYALRQDPFNLSISMFERLVEN-DMEYTRLTMQRRMHPQIRRLVSSVY--- 793 Query: 466 KIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESREN 525 ++ ++ +Y G+I F+ S+ E+ G S+ N Sbjct: 794 --------EDLSDYEITKYWPSIPGMGEIRR-----FFLTHSRIEDN-----DGFASKIN 835 Query: 526 PLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPED-------VEVKTVDGY 578 EA+++ + L++ GV+P+ I +T Y Q+DLI + E ++V TVDGY Sbjct: 836 LFEAQMLVQFAVYLINNGVEPQKITCLTFYAAQKDLIERLLSESLNREKHFIKVATVDGY 895 Query: 579 QGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLS 629 QG E +V++LSLVR+N E+GFL R+ VSL+RA+R L + G++ ++ Sbjct: 896 QGEENDVVLLSLVRNNDRTEVGFLSSPHRVCVSLSRARRGLFIFGNAQLVA 946 >gb|AAF79736.1|AC005106_17 (AC005106) T25N20.11 [Arabidopsis thaliana] Length = 1048 Score = 99.1 bits (243), Expect = 1e-19 Identities = 100/335 (29%), Positives = 164/335 (48%), Gaps = 60/335 (17%) Query: 360 VVLTTNSSAAL---EVVDYDTYDVAIIDEATQSTIPSILIPLNKV----ERFVLAGDHKQ 412 +V++T SA+L E V+ + ++DEA Q++ P +I ++ + VLAGD +Q Sbjct: 564 LVVSTYMSASLLNAEGVNRGHFTHILLDEAGQASEPENMIAVSNLCLTETVVVLAGDPRQ 623 Query: 413 LPPTILSLEAQELS--RTLFEGLIE---------RYPWKSEMLVVQYRMNERIMEFPSKE 461 L P I S +A+ L ++ E L E Y K LV YR + I++ PSK Sbjct: 624 LGPVIYSRDAESLGLGKSYLERLFECDYYCEGDENYVTK---LVKNYRCHPEILDLPSKL 680 Query: 462 FYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSE 521 FY G+++A + L L + N E +VF + +R G+ Sbjct: 681 FYDGELVASKEDTDSVLASL----------NFLPNKEFPMVFYGIQGCD-----EREGNN 725 Query: 522 -SRENPLEAEIVAKIVDKLLSIG-VKPEWIGVITPYDDQ----RDLISMKVPEDVEVKTV 575 S N +E V + + +L + V+ E IGVITPY Q ++++ +V+V +V Sbjct: 726 PSWFNRIEISKVIETIKRLTANDCVQEEDIGVITPYRQQVMKIKEVLDRLDMTEVKVGSV 785 Query: 576 DGYQGREKEVIILSLVRSN-KLGE------IGFLKDLRRLNVSLTRAKRKLIVVGDSSTL 628 + +QG+EK+VII+S VRS K E +GFL + RR NV++TRA L+++G+ + Sbjct: 786 EQFQGQEKQVIIISTVRSTIKHNEFDRAYCLGFLSNPRRFNVAITRAISLLVIIGNPHII 845 Query: 629 SSHETYKKM----IEFFKEKGC-------FIEFPF 652 + K+ ++ +GC F+E PF Sbjct: 846 CKDMNWNKLLWRCVDNNAYQGCGLPEQEEFVEEPF 880 >gb|AAF58307.1| (AE003816) CG6701 gene product [Drosophila melanogaster] Length = 1194 Score = 96.3 bits (236), Expect = 9e-19 Identities = 86/295 (29%), Positives = 145/295 (49%), Gaps = 40/295 (13%) Query: 376 DTYDVAIIDEATQSTIPSILI----PLNKVERFVLAGDHKQLPPTILSLEAQE--LSRTL 429 + Y +DEA ST +L+ L+ +L+GDHKQL P + S A E L TL Sbjct: 618 NVYTHVFVDEAAASTEAEVLMGITCTLSPTLNLILSGDHKQLGPVLQSQRANEWGLGLTL 677 Query: 430 FEGLIERYPWKSE-----------MLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITL 478 FE L++R ++ E L+ +R + I+ + +Y G + E+ I Sbjct: 678 FERLLQRKCYQVEEDGSYNASVQTRLIRNFRSHPEIVSLYNNMYYEGHL-RTEAPMEIVC 736 Query: 479 RDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDK 538 R + PN ++ + + VF T ++ S S N E ++V V Sbjct: 737 RFHNWFYLPNATFPIMFHS----VFGTTMNTKS--------SVSLCNNKEIDVVMDYVKD 784 Query: 539 LLSIGVKPEW-----IGVITPYDDQ----RDLISMKVPEDVEVKTVDGYQGREKEVIILS 589 L+ G+ E IG+I+PY +Q ++ ++M+ ++ +V+ +QG+EK VII+S Sbjct: 785 LMYFGLNGEKLLQTDIGIISPYKNQYQRIQEQLNMRNWSQIDCGSVELFQGKEKHVIIVS 844 Query: 590 LVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEK 644 VRS ++GFL + RRLNV L+R LI++G+ TLS + ++ +IE + + Sbjct: 845 FVRSFT-PKLGFLNNERRLNVLLSRPISLLILIGNPRTLSQNSDFQHIIEMCRNR 898 >dbj|BAA92642.1| (AB037825) KIAA1404 protein [Homo sapiens] Length = 1925 Score = 95.2 bits (233), Expect = 2e-18 Identities = 88/313 (28%), Positives = 149/313 (47%), Gaps = 35/313 (11%) Query: 344 RKLEERIARD--IIREADVVLTTNSSAAL--EVVDYDTYDVAIIDEATQSTIPSILIPLN 399 R E R+ D I+++A VV T + AA +++ + I++EA + + L+ Sbjct: 969 RMAELRLQEDLHILKDAQVVGMTTTGAAKYRQILQKVEPRIVIVEEAAEVLEAHTIATLS 1028 Query: 400 KV-ERFVLAGDHKQLPPTILSLEAQE---LSRTLFEGLIE-RYPWKSEMLVVQYRMNERI 454 K + +L GDH+QL P+ + + L +LFE L++ P+ L Q+RM I Sbjct: 1029 KACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFERLVKVNIPFVR--LNYQHRMCPEI 1086 Query: 455 MEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWE 514 + Y +DL + S + KI + + F++ N E Sbjct: 1087 ARLLTPHIY---------------QDLENHPSVL-KYEKIKGVSSNLFFVE----HNFPE 1126 Query: 515 RQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQ----RDLISMKVPEDV 570 ++ + +S +N EA V ++ L P I ++T Y Q R L+ K V Sbjct: 1127 QEIQEGKSHQNQHEAHFVVELCKYFLCQEYLPSQITILTTYTGQLFCLRKLMPAKTFAGV 1186 Query: 571 EVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSS 630 V VD YQG E ++I+LSLVRSN+ G++GFL+ R+ V+L+RAK+ + +G+ L+ Sbjct: 1187 RVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQISNRICVALSRAKKGMYCIGNMQMLAK 1246 Query: 631 HETYKKMIEFFKE 643 + K+I +E Sbjct: 1247 VPLWSKIIHTLRE 1259 >dbj|BAB14696.1| (AK023836) unnamed protein product [Homo sapiens] Length = 1137 Score = 95.2 bits (233), Expect = 2e-18 Identities = 88/313 (28%), Positives = 149/313 (47%), Gaps = 35/313 (11%) Query: 344 RKLEERIARD--IIREADVVLTTNSSAAL--EVVDYDTYDVAIIDEATQSTIPSILIPLN 399 R E R+ D I+++A VV T + AA +++ + I++EA + + L+ Sbjct: 254 RMAELRLQEDLHILKDAQVVGMTTTGAAKYRQILQKVEPRIVIVEEAAEVLEAHTIATLS 313 Query: 400 KV-ERFVLAGDHKQLPPTILSLEAQE---LSRTLFEGLIE-RYPWKSEMLVVQYRMNERI 454 K + +L GDH+QL P+ + + L +LFE L++ P+ L Q+RM I Sbjct: 314 KACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFERLVKVNIPFVR--LNYQHRMCPEI 371 Query: 455 MEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWE 514 + Y +DL + S + KI + + F++ N E Sbjct: 372 ARLLTPHIY---------------QDLENHPSVL-KYEKIKGVSSNLFFVE----HNFPE 411 Query: 515 RQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQ----RDLISMKVPEDV 570 ++ + +S +N EA V ++ L P I ++T Y Q R L+ K V Sbjct: 412 QEIQEGKSHQNQHEAHFVVELCKYFLCQEYLPSQITILTTYTGQLFCLRKLMPAKTFAGV 471 Query: 571 EVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSS 630 V VD YQG E ++I+LSLVRSN+ G++GFL+ R+ V+L+RAK+ + +G+ L+ Sbjct: 472 RVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQISNRICVALSRAKKGMYCIGNMQMLAK 531 Query: 631 HETYKKMIEFFKE 643 + K+I +E Sbjct: 532 VPLWSKIIHTLRE 544 >pir||T42668 hypothetical protein DKFZp434B0717.1 - human (fragment) >gi|6453506|emb|CAB61391.1| (AL133068) hypothetical protein [Homo sapiens] Length = 678 Score = 94.8 bits (232), Expect = 3e-18 Identities = 122/444 (27%), Positives = 193/444 (42%), Gaps = 79/444 (17%) Query: 262 LITQHELYGELRELRVI--GQSLAEKRDTYTKPTPKFRRGLSDEEIIKLAERKRGARGLS 319 L + L G+ R L I G K T + + L D I+ A A + Sbjct: 218 LAVKRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHFALPDSRILVCAPSNSAADLVC 277 Query: 320 ARL----IMEMAEWIKLNR--QVQKAFDDARKLEERIARDIIREAD--VVLTTNSSAALE 371 RL ++ A +++N + ++ DA K R DI + + +++TT SS+ L Sbjct: 278 LRLHESKVLRPATMVRVNATCRFEEIVIDAVKPYCRDGEDIWKASRFRIIITTCSSSGLF 337 Query: 372 V---VDYDTYDVAIIDEATQSTIPSILIPLNKVE----RFVLAGDHKQLPPTILSLEAQE 424 V + +DEA Q++ P LIPL + + VLAGD QL P I S A Sbjct: 338 YQIGVRVGHFTHVFVDEAGQASEPECLIPLGLMSDISGQIVLAGDPMQLGPVIKSRLAMA 397 Query: 425 --LSRTLFEGLIERYPWKSE----------------MLVVQYRMNERIMEFPSKEFYGGK 466 L+ + E L+ R ++ + LV YR +E ++ PS+ FY + Sbjct: 398 YGLNVSFLERLMSRPAYQRDENAFGACGAHNPLLVTKLVKNYRSHEALLMLPSRLFYHRE 457 Query: 467 --IIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRE 524 + AD +V L W K+ ++F RGSE+RE Sbjct: 458 LEVCADPTVVTSLL-----------GWEKLPKKGFPLIFHGV-----------RGSEARE 495 Query: 525 -------NPLEAEIVAK---IVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE----DV 570 NP EA V + ++ +S V IGVITPY Q + I + + D+ Sbjct: 496 GKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQVEKIRILLRNVDLMDI 555 Query: 571 EVKTVDGYQGREKEVIILSLVRSNK------LGEIGFLKDLRRLNVSLTRAKRKLIVVGD 624 +V +V+ +QG+E VII+S VRSN+ +GFL + +R NV++TR K LIV+G+ Sbjct: 556 KVGSVEEFQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGN 615 Query: 625 SSTLSSHETYKKMIEFFKEKGCFI 648 L + ++E+ G ++ Sbjct: 616 PHVLVRDPCFGALLEYSITNGVYM 639 >pir||T47242 DNA helicase homolog - fission yeast (Schizosaccharomyces pombe) (fragment) >gi|3329511|gb|AAC39502.1| (AF075169) DNA helicase homolog [Schizosaccharomyces pombe] Length = 191 Score = 93.2 bits (228), Expect = 8e-18 Identities = 63/189 (33%), Positives = 97/189 (50%), Gaps = 14/189 (7%) Query: 378 YDVAIIDEATQSTIPSILIPLNKVERFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIE 435 +D IIDEA+Q +P L PL E+FVL GDH QLPP + + + LS +LF+ L E Sbjct: 6 FDYCIIDEASQIPLPICLGPLQLAEKFVLVGDHYQLPPLVKNSRTSKDGLSLSLFKLLSE 65 Query: 436 RYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADES--------VRGITLRDLVEYQSP 487 ++P L +QYRMNE I S+ YGG ++ + L D + S Sbjct: 66 KHPEAVTTLRLQYRMNEDINSLSSELIYGGNLVCGSKTISQKKLILPKAHLSDGLPDSSS 125 Query: 488 NDSW-GKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKP 546 + W K++NP + ++F +T ++ + + + EN EA ++ + V L GVK Sbjct: 126 SLHWVNKLINPSHSVIFFNT---DDILGVESKTNNILENHTEAFLIEQAVSSFLERGVKQ 182 Query: 547 EWIGVITPY 555 IG+I+ Y Sbjct: 183 SSIGIISIY 191 >gb|AAF47775.1| (AE003478) CG11513 gene product [Drosophila melanogaster] Length = 1274 Score = 92.1 bits (225), Expect = 2e-17 Identities = 83/297 (27%), Positives = 143/297 (47%), Gaps = 47/297 (15%) Query: 382 IIDEATQSTIPSILIPL----NKVERFVLAGDHKQLPPTILSLEAQEL--SRTLFEGLIE 435 + DEA Q T P ++P+ K + VL+GD +QL + S A ++ S + E L+E Sbjct: 946 LFDEAGQCTEPETMVPIVMLTKKRSQVVLSGDPRQLQSIVTSRIASKMGFSISFLERLLE 1005 Query: 436 RYPWKSEM----------------LVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLR 479 R P++ ++ L+ YR IM S+ FY ++I S + Sbjct: 1006 RSPYRKDLQRFPESSGYNPLVLTKLLYNYRALPSIMSIYSRLFYDDELIPVLSEKDSRES 1065 Query: 480 DLVE-----YQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAK 534 L+ ++S D P+ F EN RQ S S NP E V Sbjct: 1066 RLLSKLRCVFESEKDI------PQAHGTFFYGIIGEN---RQNNDSPSWFNPQEVREVFL 1116 Query: 535 IVDKLLSIGVKPEWIGVITPYDDQRDLI-SMKVPEDV---EVKTVDGYQGREKEVIILSL 590 + L V + IG+ITPY Q ++ SM + DV ++ +V+ +QG+E+++I++S Sbjct: 1117 MTIALYRANVTADQIGIITPYQKQVKMLRSMFIGTDVVMPKIGSVEEFQGQERDIILIST 1176 Query: 591 VRSNK-------LGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEF 640 VRS++ +GF++ +RLNV+++RA+ +I+ G+ L+ E ++++I F Sbjct: 1177 VRSSEEILRMDARFSLGFVRCSKRLNVAVSRARAMMIIFGNPHLLAVDECWRQLILF 1233 >gi|6678920 Moloney leukemia virus 10 [Mus musculus] >gi|127560|sp|P23249|MV10_MOUSE PROTEIN MOV-10 >gi|110821|pir||A39611 probable GTP-binding protein - mouse >gi|53169|emb|CAA36803.1| (X52574) GTP binding protein [Mus musculus] Length = 1004 Score = 91.7 bits (224), Expect = 2e-17 Identities = 103/358 (28%), Positives = 163/358 (44%), Gaps = 73/358 (20%) Query: 351 ARDIIREADVVLTTNSSAALEV-----VDYDTYDVAIIDEATQSTIPSILIPL------- 398 A+ +++ V++TT +A+ V +D+ T+ IDEA P L+ + Sbjct: 610 AKKHLQQYRVLITTLITASRLVSAQFPIDHFTH--IFIDEAGHCMEPESLVAIAGLMDVK 667 Query: 399 ---NKVERFVLAGDHKQLPPTILSLEAQELSRTLFEGLIERY---------------PWK 440 N + VLAGD +QL P + S A L L L+ER P Sbjct: 668 ETGNPGGQLVLAGDPRQLGPVLRSPLA--LKHGLGYSLLERLLAYNSLYKKGPNGYDPQF 725 Query: 441 SEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENV 500 L+ YR + I++ P++ +Y G++ A D+V+ + W + Sbjct: 726 ITKLLRNYRSHPTILDIPNQLYYDGELQA--------CADVVDRER-FCRWEGLPQQGFP 776 Query: 501 IVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVK-------PEWIGVIT 553 I+F K ER+ S S NP EA V + +LL+ K P +GVI+ Sbjct: 777 IIFHGVM---GKDEREGN-SPSFFNPEEAATVTSYLKQLLAPSSKKGKARLSPRNVGVIS 832 Query: 554 PYDDQ------------RDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNKLG---- 597 PY Q R+L + +D++V +V+ +QG+E+ VI++S VRS++ Sbjct: 833 PYRKQVEKIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLD 892 Query: 598 ---EIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGCFIEFPF 652 +GFLK+ +R NV++TRAK LIVVG+ L +K +EF KE G + PF Sbjct: 893 LDFNLGFLKNPKRFNVAVTRAKALLIVVGNPLLLGHDPDWKTFLEFCKENGGYTGCPF 950 >dbj|BAB13457.1| (AB046851) KIAA1631 protein [Homo sapiens] Length = 1032 Score = 90.5 bits (221), Expect = 5e-17 Identities = 106/366 (28%), Positives = 169/366 (45%), Gaps = 70/366 (19%) Query: 342 DARKLEERI-ARDIIREADVVLTTNSSAALEV-----VDYDTYDVAIIDEATQSTIPSIL 395 DA+K E A+ ++E V++TT +A V +D+ T+ IDEA P L Sbjct: 628 DAKKGEYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTH--IFIDEAGHCMEPESL 685 Query: 396 IPLNKVE----------RFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLI--------- 434 + + + + VLAGD +QL P + S Q+ L +L E L+ Sbjct: 686 VAIAGLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKG 745 Query: 435 -ERY-PWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWG 492 + Y P L+ YR + I++ P++ +Y G++ A D+V+ + W Sbjct: 746 PDGYDPQFITKLLRNYRSHPTILDIPNQLYYEGELQA--------CADVVDRER-FCRWA 796 Query: 493 KILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVK------- 545 + I+F K ER+ S S NP EA V + LL+ K Sbjct: 797 GLPRQGFPIIFHGVM---GKDEREGN-SPSFFNPEEAATVTSYLKLLLAPSSKKGKARLS 852 Query: 546 PEWIGVITPYDDQ------------RDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRS 593 P +GVI+PY Q R+L + +D++V +V+ +QG+E+ VI++S VRS Sbjct: 853 PRSVGVISPYRKQVEKIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRS 912 Query: 594 NKLG-------EIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGC 646 ++ +GFLK+ +R NV++TRAK LI+VG+ L +K +EF KE G Sbjct: 913 SQSFVQLDLDFNLGFLKNPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCKENGG 972 Query: 647 FIEFPF 652 + PF Sbjct: 973 YTGCPF 978 >emb|CAB63041.1| (AL022328) dJ402G11.8 (novel protein similar to mouse MOV10 (GB110) and yeast and plant predicted proteins) [Homo sapiens] Length = 417 Score = 90.1 bits (220), Expect = 7e-17 Identities = 105/362 (29%), Positives = 162/362 (44%), Gaps = 73/362 (20%) Query: 335 QVQKAFDDARKLEERIARDIIREADVV-LTTNSSAALE---VVDYDTYDVAIIDEATQST 390 QV A D+R L + AD+V L + S L+ +V + +DEA Q++ Sbjct: 42 QVHFALPDSRIL---VCAPSNSAADLVCLRLHESKVLQPATMVRVGHFTHVFVDEAGQAS 98 Query: 391 IPSILIPLNKVE----RFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIERYPWKSE-- 442 P LIPL + + VLAGD QL P I S A L+ + E L+ R ++ + Sbjct: 99 EPECLIPLGLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDEN 158 Query: 443 --------------MLVVQYRMNERIMEFPSKEFYGGK--IIADESVRGITLRDLVEYQS 486 LV YR +E ++ PS+ FY + + AD +V L Sbjct: 159 AFGACGAHNPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLL-------- 210 Query: 487 PNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRE-------NPLEAEIVAK---IV 536 W K+ ++F RGSE+RE NP EA V + ++ Sbjct: 211 ---GWEKLPKKGFPLIFHGV-----------RGSEAREGKSPSWFNPAEAVQVLRYCCLL 256 Query: 537 DKLLSIGVKPEWIGVITPYDDQRDLISMKVPE----DVEVKTVDGYQGREKEVIILSLVR 592 +S V IGVITPY Q + I + + D++V +V+ +QG+E VII+S VR Sbjct: 257 AHSISSQVSASDIGVITPYRKQVEKIRILLRNVDLMDIKVGSVEEFQGQEYLVIIISTVR 316 Query: 593 SNK------LGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGC 646 SN+ +GFL + +R NV++TR K LIV+G+ L + ++E+ G Sbjct: 317 SNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRDPCFGALLEYSITNGV 376 Query: 647 FI 648 ++ Sbjct: 377 YM 378 >dbj|BAA90895.1| (AK000033) unnamed protein product [Homo sapiens] Length = 338 Score = 87.8 bits (214), Expect = 3e-16 Identities = 91/310 (29%), Positives = 141/310 (45%), Gaps = 66/310 (21%) Query: 383 IDEATQSTIPSILIPLNKVE----RFVLAGDHKQLPPTILSLEAQE--LSRTLFEGLIER 436 +DEA Q++ P LIPL + + VLAGD QL P I S A L+ + E L+ R Sbjct: 12 VDEAGQASEPECLIPLGLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSR 71 Query: 437 YPWKSE----------------MLVVQYRMNERIMEFPSKEFYGGK--IIADESVRGITL 478 ++ + LV YR +E ++ PS+ FY + + AD +V L Sbjct: 72 PAYQRDENAFGACGAHNPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLL 131 Query: 479 RDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRE-------NPLEAEI 531 W K+ ++F RGSE+RE NP EA Sbjct: 132 -----------GWEKLPKKGFPLIFHGV-----------RGSEAREGKSPSWFNPAEAVQ 169 Query: 532 VAK---IVDKLLSIGVKPEWIGVITPYDDQRDLISMKVPE----DVEVKTVDGYQGREKE 584 V + ++ +S V +GVITPY Q + I + + D++V +V+ QG+E Sbjct: 170 VLRYCCLLAHSISSQVSASDVGVITPYRKQVEKIRILLRNVDLMDIKVGSVEELQGQEYL 229 Query: 585 VIILSLVRSNK------LGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMI 638 VII+S VRSN+ +GFL + +R NV++TR K LIV+G+ L + ++ Sbjct: 230 VIIISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRDPCFGALL 289 Query: 639 EFFKEKGCFI 648 E+ G ++ Sbjct: 290 EYSITNGVYM 299 >emb|CAC15527.1| (AL121829) dJ697K14.7 (putative novel protein) [Homo sapiens] Length = 451 Score = 85.0 bits (207), Expect = 2e-15 Identities = 95/341 (27%), Positives = 150/341 (43%), Gaps = 78/341 (22%) Query: 337 QKAFDDARKLEERIARDIIREADVVLTTNS---SAALEVVDYDTYDVAIIDEATQSTIPS 393 +K +ARK E + +V+L T S SA+L+++D ++DEA +T P Sbjct: 84 KKVLWEARKFE-------LDRHEVILCTCSCAASASLKILDVRQI---LVDEAGMATEPE 133 Query: 394 ILIPL---NKVERFVLAGDHKQLPPTILSLEAQELSRTLFEGLIERYPWKSEMLVVQYRM 450 LIPL + E+ VL GDHKQL P + + Q L L L ERY + ML QYRM Sbjct: 134 TLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNLG--LDRSLFERYHEDAHMLDTQYRM 191 Query: 451 NERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDS----WGKILNPENVIVFIDT 506 +E I FPS FY K+ ++ +G+ V + +S +G + E ++ Sbjct: 192 HEGICAFPSVAFYKSKL---KTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTD 248 Query: 507 SKAENKWERQRRGSESRENPLEAEIVAKIVDKL-LSIGVKPEWIGVITPYDDQRDLISMK 565 EN S+ N E V +I +L L V+P+ I V+TPY+ Q IS Sbjct: 249 EGNEN----------SKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKA 298 Query: 566 VPED----VEVKTVDGYQGR-------------------------EKEVIILSLVRSNKL 596 + + V V ++ QG E +++S VR+ Sbjct: 299 LRREGIAGVAVSSITKSQGEAGGSWVGPGGWAQRQQGLTSHPAGSEWRYVLVSTVRTCAK 358 Query: 597 GE-------------IGFLKDLRRLNVSLTRAKRKLIVVGD 624 + +GF+ D ++NV++TRA+ L ++G+ Sbjct: 359 SDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGE 399 >pir||G64575 conserved hypothetical protein HP0447 - Helicobacter pylori (strain 26695) >gi|2313555|gb|AAD07514.1| (AE000560) conserved hypothetical protein [Helicobacter pylori 26695] Length = 360 Score = 84.3 bits (205), Expect = 4e-15 Identities = 91/310 (29%), Positives = 149/310 (47%), Gaps = 44/310 (14%) Query: 363 TTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKV-ERFVLAGDHKQLPPTI---- 417 T + ALE + +D I+DEA ++ +L+ + ER +L GD +QLP + Sbjct: 53 TGQHNQALERKETPYFDSVIVDEAAKANPLELLMVMALAKERIILVGDDRQLPHYLDDEI 112 Query: 418 ---LSLEAQE--------LSRTLFEGLIERYPWKSEM--------LVVQYRMNERIMEFP 458 L E+Q+ L ++F+ L ER E+ L +QY M+ + E Sbjct: 113 GKKLEDESQDAQDEIEKALKDSMFKKLKERAQKLKELDGKECFITLNMQYGMHPLLGELV 172 Query: 459 SKEFYGGKIIADES-VRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQR 517 S FY + ES ++G L + P ++L+ + +ID E+K +R Sbjct: 173 SDVFYKPHNESFESPLKGKHLEE-----KPFKHNLRVLD-NKPLAWIDVK--ESKEKRNA 224 Query: 518 RGSESRENPLEAEIVAKIVDKLLSIGVKPE---WIGVITPYDDQRDLI--SMKVPEDVEV 572 GS RE+ + A + + L + +K E GVIT + +Q+ L+ ++K ++E+ Sbjct: 225 DGSYYRESEITA------IKECLDLFMKDEPDFTFGVITFFSEQKRLLEQALKGYANLEI 278 Query: 573 KTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHE 632 TVD +QG+E +V+ LS VR+ GFLK L V+L+R KR LIV GD + E Sbjct: 279 GTVDSFQGKEFDVVFLSSVRTRHTEGFGFLKISSCLCVALSRQKRALIVAGDREKFDTPE 338 Query: 633 TYKKMIEFFK 642 + K+ F+ Sbjct: 339 SKDKVSGLFE 348 >pir||B75198 DNA helicase related protein PAB0067 - Pyrococcus abyssi (strain Orsay) >gi|5457542|emb|CAB49033.1| (AJ248283) DNA HELICASE RELATED PROTEIN [Pyrococcus abyssi] Length = 1308 Score = 83.1 bits (202), Expect = 9e-15 Identities = 129/517 (24%), Positives = 208/517 (39%), Gaps = 145/517 (28%) Query: 171 LNRSQRKAISKALGSEDFFLVHGPFGTGKTRTLVELIRQEVKRGNKVLATAESNVAVDNL 230 LN QRK + + GP GTGKT + VLA A S + Sbjct: 839 LNEDQRKFVLDI--DHRIVTLQGPPGTGKTSGAI---------APAVLARAYSTI----- 882 Query: 231 VERLSRSGIKIVRIGHPSRVSKHLHETTLAYLITQHELYGELRELRVIGQSLAEKRDTYT 290 + +S + IV + H LI + L EL+ ++ + Sbjct: 883 --KQGKSALFIV--------TALSHRAVNEALIRTYRLKEELKNIKEL------------ 920 Query: 291 KPTPKFRRGLSDEEIIKLAERKRGARGLSARLIMEMAEWIKLNRQVQKAFDDARKLEERI 350 + RG+S EE I+ +R+ G IK++ + + F + Sbjct: 921 -KNVELIRGVSGEEAIEPMKRELGG--------------IKVDIRARFTFSKST------ 959 Query: 351 ARDIIREADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSILIPLNKVE-RFVLAGD 409 + ++ T + V +Y+ D+ +IDEA+ +P L+ + + +L GD Sbjct: 960 ---LFPTVKILFATPQTVFKLVKNYEA-DLVVIDEASMMDLPMFLLATKNAKGQVLLVGD 1015 Query: 410 HKQLPPTIL-----------------------------SLEAQELSRTLFEGLIERYP-- 438 H+Q+ P + LE +EL R F+ ++ R P Sbjct: 1016 HRQMQPIQVHEWELEDRKTIEEHLPFLSALNFIRFLRGELEERELKR--FKRILGRNPPK 1073 Query: 439 WKSEM--------LVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSP--- 487 WK + L +R+ + + E S+ FY S GI LR E Sbjct: 1074 WKVDKEDVLPMHRLRETFRLPQALAELHSELFY--------SFDGIKLRSRKEPSEEIAR 1125 Query: 488 -------NDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLL 540 N+ IL+P+ +V I GS S+ N LEA IV +IV+ L Sbjct: 1126 ALRNAGKNEFLRFILDPDYPVVLI---------VHDENGS-SKVNELEAGIVKEIVEALN 1175 Query: 541 SIGVKPEWIGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNK---LG 597 + V GV+ PY Q+ LI V +V+V TV+ +QG E+++II+S+ S+ L Sbjct: 1176 GVDV-----GVVVPYRAQKRLIRSLV--NVQVDTVERFQGGERDIIIVSMTSSDPSYLLK 1228 Query: 598 EIGFLKDLRRLNVSLTRAKRKLIVVGDSS--TLSSHE 632 + FL D RLNV+ +RA+ KLI++ + TLS+ + Sbjct: 1229 VMDFLYDPNRLNVAGSRAREKLILIASRNLFTLSARD 1265 >emb|CAB60444.1| (AL132853) cDNA EST yk10h1.5 comes from this gene~cDNA EST yk27d4.5 comes from this gene~cDNA EST yk42b2.5 comes from this gene~cDNA EST yk49b5.5 comes from this gene~cDNA EST yk147h7.5 comes from this gene~cDNA EST yk192e10.5 comes from this gene~cDNA> Length = 1212 Score = 82.7 bits (201), Expect = 1e-14 Identities = 87/299 (29%), Positives = 139/299 (46%), Gaps = 46/299 (15%) Query: 354 IIREADVVLTTNSSAAL---EVVDYD-TYDVAIIDEATQSTIPSILIPL---------NK 400 +++EA ++ T + AAL E+V YD +++EA Q IPL N+ Sbjct: 710 LVKEAKIIAMTCTHAALRRNELVKLGFRYDNIVMEEAAQILEVETFIPLLLQNPQDGHNR 769 Query: 401 VERFVLAGDHKQLPPTILSLEAQELS---RTLFEGLIERYPWKSEMLVVQYRMNERIMEF 457 ++R+++ GDH QLPP + + Q+ S ++LF L+ R + L Q R +I E Sbjct: 770 LKRWIMIGDHHQLPPVVQNQAFQKYSNMEQSLFARLV-RLSVPNVQLDRQGRARAQIAEL 828 Query: 458 PSKEFYG-GKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQ 516 + G G + V G L ++Q+ N + FID E Q Sbjct: 829 YQWRYNGLGNL---PHVDG-----LPQFQNANAGFAFPFQ------FIDIPDFNGHGETQ 874 Query: 517 RRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRDLI----------SMKV 566 +N EAE + + +G E I ++T Y+ Q LI + + Sbjct: 875 P-SPHFYQNLGEAEYACALYTYMRILGYPAEKISILTTYNGQAQLIRDVFQRRCDTNPLI 933 Query: 567 PEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDS 625 +V TVD YQG++ + IILSLV++ +G I +D+RRL V+L+RA+ L V+G S Sbjct: 934 GMPAKVSTVDKYQGQQNDFIILSLVKTRNIGHI---RDVRRLVVALSRARLGLYVLGRS 989 >pir||T46441 hypothetical protein DKFZp434C0927.1 - human >gi|6808062|emb|CAB70881.1| (AL137700) hypothetical protein [Homo sapiens] Length = 239 Score = 82.7 bits (201), Expect = 1e-14 Identities = 65/209 (31%), Positives = 100/209 (47%), Gaps = 32/209 (15%) Query: 440 KSEMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPEN 499 K +L QYR + I + FY G ++ G+T + +SP W L N Sbjct: 4 KPILLRTQYRCHPAISAIANDLFYKGALM-----NGVTEIE----RSPLLEWLPTLCFYN 54 Query: 500 VIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQR 559 V K Q S N EA K++ L++ G+ IGVIT Y Q Sbjct: 55 V-----------KGLEQIERDNSFHNVAEATFTLKLIQSLIASGIAGSMIGVITLYKSQM 103 Query: 560 -------DLISMKVPE--DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNV 610 + P+ V+V TVD +QG EKE+IILS VR+ ++GF+ +R+NV Sbjct: 104 YKLCHLLSAVDFHHPDIKTVQVSTVDAFQGAEKEIIILSCVRTR---QVGFIDSEKRMNV 160 Query: 611 SLTRAKRKLIVVGDSSTLSSHETYKKMIE 639 +LTR KR L++VG+ + L ++ + ++I+ Sbjct: 161 ALTRGKRHLLIVGNLACLRKNQLWGRVIQ 189 >pir||T27684 hypothetical protein ZK1067.2 - Caenorhabditis elegans >gi|3881525|emb|CAA93884.1| (Z70038) cDNA EST yk19a4.3 comes from this gene~cDNA EST yk19a4.5 comes from this gene~cDNA EST yk224b3.5 comes from this gene~cDNA EST yk357f10.5 comes from this gene~cDNA EST yk518c10.5 comes from this gene [Caenorhabditis elegans] Length = 2219 Score = 81.5 bits (198), Expect = 3e-14 Identities = 101/392 (25%), Positives = 181/392 (45%), Gaps = 59/392 (15%) Query: 278 IGQSLAEKRDTYTKPTPKFRRGLSD-EEIIKLAERKRGARGLSARLIMEMAEWIKLNRQV 336 I ++E +D P ++ L+D + I LA KR + ++ + L RQ+ Sbjct: 1124 INNLVSEIKDMILSSQPVPKKDLNDIKYIFSLARLKRWSLYITWCDALRSIVTENLPRQI 1183 Query: 337 QK---AFDDARKLEERIARDIIREADVV--LTTNSSAALEVVDYDTYDVAIIDEATQSTI 391 ++ A ++ + + R+ +I+R ++ TT S ++ + I++EA + Sbjct: 1184 REYREACENFKNAQNRVDAEIMRMTMIIGATTTGCSRLRPTLEKVGPRILIVEEAAEVLE 1243 Query: 392 PSILIPL-NKVERFVLAGDHKQLPPTILSLE---AQELSRTLFEGLIER-YPWKSEMLVV 446 I+ + + VE V+ GDHKQL P E A L ++FE L+ER P+ L Sbjct: 1244 AHIISAMISTVEHVVMIGDHKQLRPNPAVHELGVAYGLRISMFERLVERGLPFSQ--LRQ 1301 Query: 447 QYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPE------NV 500 Q+RMN I+D+ V+ L Y + D+ L P+ N+ Sbjct: 1302 QHRMN--------------LTISDKIVK------LSFYDNVTDAENVGLYPDVQGMATNL 1341 Query: 501 IVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQRD 560 + TS E+ E S N E + +V LL I V+ Y Q++ Sbjct: 1342 FFWSHTSMEESPDE------VSWLNKHEISMTVALVKHLLKQNYTTNDIVVLATYSAQKN 1395 Query: 561 LISMK-------VPED--VEVKTVDGYQGREKEVIILSLVRSNKLGE----IGFLKDLRR 607 L+ + P+ + V+TVD +QG+E++++I+SLVRS++ G IGFL R Sbjct: 1396 LMYREYANVFGSTPDSNVIPVETVDSFQGKERKIVIVSLVRSHRGGRENTGIGFLAVANR 1455 Query: 608 LNVSLTRAKRKLIVVGDSS-TLSSHETYKKMI 638 + V+LTRA+ + ++G+ + +++ E + K++ Sbjct: 1456 ICVALTRAQHGMYIIGNGAYIMNNSELWNKIV 1487 >pir||T23039 hypothetical protein H03G16.3 - Caenorhabditis elegans >gi|3877990|emb|CAB07226.1| (Z92790) H03G16.3 [Caenorhabditis elegans] Length = 646 Score = 81.1 bits (197), Expect = 3e-14 Identities = 89/323 (27%), Positives = 141/323 (43%), Gaps = 55/323 (17%) Query: 353 DIIREADVVLTTNSSAALE-VVDYDTYDVA--IIDEATQSTIPSILIPLNKVERFVLAGD 409 D+I VVL T + L V + D + IIDEA + K + FV+AGD Sbjct: 196 DMIGNVLVVLATIGADFLNFVAKQEALDPSFCIIDEAGLVMASETWPDVYKSKGFVIAGD 255 Query: 410 HKQLPPTILS-------------LEAQELSRTLFEGLIERYPWKSE-----MLVVQYRMN 451 +L P I + LE + L + +++ K+E +L QYR N Sbjct: 256 PNELFPQIYNHDNGNGFFNQFCCLEQKRLETQV--SILDCINEKTENLSPIILDTQYRSN 313 Query: 452 ERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPE-NVIVFIDTSKAE 510 E IM + + FY K+ D +TLR + G NP + V +DTS E Sbjct: 314 ETIMAWSNACFYNPKVKTDFKCGSLTLRSFFK--------GSKFNPLFHPFVIVDTS-CE 364 Query: 511 NKWERQRRG-----------SESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQR 559 + E++ +E N EA+I +LL + V+ I +ITPY Q Sbjct: 365 KEMEKRNETFEYLVFNNNNENEGYANVAEAKIAMHHYKQLLKLKVQASDIAIITPYRGQS 424 Query: 560 DLISMKVPE-----------DVEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRL 608 ++ + + D V VD G+E +V+I ++VRSN ++G D RRL Sbjct: 425 HVVRQMMRKFANEESRSDCFDTHVGDVDKIVGKEFDVVIFTMVRSNPKLDMGKAGDPRRL 484 Query: 609 NVSLTRAKRKLIVVGDSSTLSSH 631 +V +T+AK+ + +G+ L+ + Sbjct: 485 HVIITKAKKHFMFIGNGFLLAEN 507 >gb|AAF54715.1| (AE003693) CG14730 gene product [Drosophila melanogaster] Length = 1170 Score = 80.8 bits (196), Expect = 4e-14 Identities = 92/333 (27%), Positives = 158/333 (46%), Gaps = 50/333 (15%) Query: 338 KAFDDARKLEERIARDIIREADVVLTTNSSAAL---EVVDYD-TYDVAIIDEATQSTIPS 393 +AF+ R +R +++EA ++ T + AAL E+V+ YD +++E+ Q Sbjct: 712 RAFELLRTGLDRSKYLLVKEAKIIAMTCTHAALKRKELVNLGFRYDNILMEESAQILEIE 771 Query: 394 ILIPL---------NKVERFVLAGDHKQLPPTILSLEAQELS---RTLFEGLIERYPWKS 441 IPL N+++R+++ GDH QLPP I ++ Q+ S ++LF L+ R + Sbjct: 772 TFIPLLLQNPLDGLNRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRLV-RLGVPT 830 Query: 442 EMLVVQYRMNERIMEFPSKEFYGGKIIADESVRGITLRDLVEYQSPNDSWGKILNPENVI 501 L Q R I Y + E ++ I RD EY+ N + NV Sbjct: 831 VDLDGQGRARASIC-----SLYKWRYKKLEDLQHIFERD--EYKQANPGFVHDYQLINVE 883 Query: 502 VFIDTSKAE-NKWERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQ-- 558 F ++E N + Q N EAE + + + +G I ++T Y+ Q Sbjct: 884 DFKGVGESEPNPYFYQ--------NLAEAEYIVAVYMYMRLLGYPAAKISILTTYNGQKH 935 Query: 559 --RDLISMKVPEDV------EVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNV 610 RD+I+ + + ++ TVD YQG++ + I++SLVR+ +G L+D+RRL V Sbjct: 936 LIRDVINARCGNNPLIGWPHKITTVDKYQGQQNDYILISLVRTK---AVGHLRDVRRLVV 992 Query: 611 SLTRAKRKLIVVGDSS----TLSSHETYKKMIE 639 +++RA+ L V G S L +T+K + + Sbjct: 993 AMSRARLGLYVFGRVSLFKNCLELQQTFKLLTQ 1025 >emb|CAB65628.1| (AL049766) dJ686N3.2 (novel protein similar to plant, yeast, worm, bacterial and human (predicted) proteins) [Homo sapiens] Length = 1814 Score = 78.4 bits (190), Expect = 2e-13 Identities = 46/134 (34%), Positives = 74/134 (54%), Gaps = 4/134 (2%) Query: 514 ERQRRGSESRENPLEAEIVAKIVDKLLSIGVKPEWIGVITPYDDQ----RDLISMKVPED 569 E++ + +S +N EA V ++ L P I ++T Y Q R L+ K Sbjct: 1015 EQEIQEGKSHQNQHEAHFVVELCKYFLCQEYLPSQITILTTYTGQLFCLRKLMPAKTFAG 1074 Query: 570 VEVKTVDGYQGREKEVIILSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLS 629 V V VD YQG E ++I+LSLVRSN+ G++GFL+ R+ V+L+RAK+ + +G+ L+ Sbjct: 1075 VRVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQISNRICVALSRAKKGMYCIGNMQMLA 1134 Query: 630 SHETYKKMIEFFKE 643 + K+I +E Sbjct: 1135 KVPLWSKIIHTLRE 1148 >pir||T29386 hypothetical protein K08D10.5 - Caenorhabditis elegans >gi|1280167|gb|AAA98031.1| (U55857) K08D10.5 gene product [Caenorhabditis elegans] Length = 602 Score = 76.9 bits (186), Expect = 7e-13 Identities = 86/345 (24%), Positives = 147/345 (41%), Gaps = 41/345 (11%) Query: 325 EMAEWIKLNRQVQKA-----FDDARKLEERIARDIIREADVVLTTNSSAALEVVDY---- 375 E EWI + ++ KA F+ K E I R ++ D L ++AA+++ Sbjct: 250 EPNEWIVMAARLLKAAVKLPFNTIPK-EINIFRVFMKLYDPQLIIGTAAAIQLAFNQPDL 308 Query: 376 ----DTYDVAIIDEATQSTIPSI--LIPLNKVERFVLAGDHKQLPPTILSLEAQELSRTL 429 D +D+ IDEA+Q + + L L R +L GD QLPP EL R Sbjct: 309 AEIKDLFDITFIDEASQLALYVLGSLATLLPKTRIILVGDMHQLPPYTEDALPAELKRAA 368 Query: 430 F-EGL---IERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIAD-ESVRGITLRDLVEY 484 E L ++ W S L +R + I + FYG + + ++V + + + +E Sbjct: 369 VGEPLTLAVKGRRWSSMHLTRVHRCPKMITDLLGAVFYGNTLTSTRKAVNRVPILEAMEL 428 Query: 485 QSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVAKIVDKLLSIGV 544 S + VF+ N +Q + +S N EA ++V L Sbjct: 429 PS-----------HHPFVFV------NYISQQTQVGKSFSNENEARYALQLVTALKRHAR 471 Query: 545 KPEW---IGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIILSLVRSNKLGEIGF 601 + + V+ Y Q + + V V T+DG QG+E +V I+ L RS+ + F Sbjct: 472 EQNTTVSVAVLNFYGAQYSYVYSIAEDGVRVNTIDGCQGQEYDVSIVLLTRSDPYEKSKF 531 Query: 602 LKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKGC 646 L + R+NV+L+R+K +V+G + +H ++ ++ C Sbjct: 532 LVNPNRINVALSRSKMATVVIGQRHLIGNHPNVQQAKRGRYQRSC 576 >sp|Q09449|YQ12_CAEEL HYPOTHETICAL 175.7 KD PROTEIN C05C10.2 IN CHROMOSOME II >gi|7495408|pir||T18941 hypothetical protein C05C10.2 - Caenorhabditis elegans >gi|3874068|emb|CAA88201.1| (Z48178) similarity with yeast NAM7 protein (Swiss Prot accession number P30771) and may possibly interact with DNA or RNA~cDNA EST yk43d4.3 comes from this gene~cDNA EST yk7f5.5 comes from this gene~cDNA EST yk68h2.5 comes from this gene~cDNA EST yk13> Length = 1551 Score = 72.6 bits (175), Expect = 1e-11 Identities = 81/298 (27%), Positives = 139/298 (46%), Gaps = 31/298 (10%) Query: 360 VVLTTNSSAALEVVDYDTYDVAIIDEATQ---STIPSILIPLNKVERFVLAGDHKQLPPT 416 V++T +S+ L + D V I DEA+Q T+ +L N F L GD QLPP Sbjct: 1186 VMVTADSAKGLLNILRDVCAVQI-DEASQLAECTLLGLLKSFNNAS-FGLIGDIHQLPPY 1243 Query: 417 ILSLEAQELSRTLFEGLIERYPWKSEMLVV-----QYRMNERIMEFPSKEFYGGKIIADE 471 +L +ER K +M V YR + + E S+ FY G +++ Sbjct: 1244 CEEGLEGKLKDFGIGNTMER-AIKEKMFPVCTLRNVYRCHPKTTELLSELFYDGALVS-- 1300 Query: 472 SVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEI 531 G++ ++ + D + NP+ ++F++ + A K S N E I Sbjct: 1301 ---GVSELARSDFMTKRDDFWP--NPKFPMMFVNNTGASTKM------GTSTSNSSEKSI 1349 Query: 532 VAKIVDKLLSIG---VKPEWIGVITPYDDQRDLISMKVP-EDVEVKTVDGYQGREKEVII 587 V +IV L++ V P IGVI+ Y Q +++ + V+ TVD +QG EKE+II Sbjct: 1350 VGEIVQNLINDPRNPVNPSDIGVISFYSAQTSILTEHLRGSGVKCGTVDAFQGSEKEIII 1409 Query: 588 LSLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLSSHETYKKMIEFFKEKG 645 + + ++ + F++ RLNV+++RAK+ I++G L + ++ ++ G Sbjct: 1410 MCST-NERISD--FMQLSNRLNVAMSRAKQVTIIIGHLDGLRRANYWSTIVNKIEQNG 1464 >pir||T23869 hypothetical protein R03D7.2 - Caenorhabditis elegans >gi|3878792|emb|CAA86856.1| (Z46828) similar to helicase domain~cDNA EST yk138d12.5 comes from this gene~cDNA EST yk138d12.3 comes from this gene [Caenorhabditis elegans] Length = 542 Score = 72.2 bits (174), Expect = 2e-11 Identities = 73/275 (26%), Positives = 120/275 (43%), Gaps = 27/275 (9%) Query: 358 ADVVLTTNSSAALEVVDYDTYDVAIIDEATQSTIPSI--LIPLNKVERFVLAGDHKQLPP 415 A + L + + LE+ D +D+ IDEA+Q + + L + R +L GD QLPP Sbjct: 198 AAIKLAFSQAPFLEIKD--RFDITFIDEASQLALYVLGSLATMLPKSRMILVGDMHQLPP 255 Query: 416 TILSLEAQELSRTLF-EGL---IERYPWKSEMLVVQYRMNERIMEFPSKEFYGGKIIADE 471 + EL R E L ++ W S L +R + I E FYG + + + Sbjct: 256 YMEEALPAELKRAAIGEPLTLAVKGRRWPSMHLTRVHRCPKMITEVLGDLFYGNTLTSSK 315 Query: 472 SVRGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEI 531 G+T +++ L + +VF+ N Q +S N EA Sbjct: 316 P--GVTDIPVLKAMG--------LPSRHPMVFV------NYTSPQTAVGKSFSNEGEARY 359 Query: 532 VAKIVDKLL---SIGVKPEWIGVITPYDDQRDLISMKVPEDVEVKTVDGYQGREKEVIIL 588 ++V+ L S K ++ Y Q + ++V V T+DG QG+E +V I+ Sbjct: 360 ALQLVEALTRYASTANKKITAAILNFYGAQYSYVYSMAEDEVTVNTIDGCQGQEYDVTIV 419 Query: 589 SLVRSNKLGEIGFLKDLRRLNVSLTRAKRKLIVVG 623 L RS+ FL + R+NV+L+R K +++G Sbjct: 420 LLTRSDPYERSKFLVNANRINVALSRPKIATVIIG 454 >pir||S75309 hypothetical protein sll1582 - Synechocystis sp. (strain PCC 6803) >gi|1652300|dbj|BAA17223.1| (D90904) hypothetical protein [Synechocystis sp.] Length = 1118 Score = 71.8 bits (173), Expect = 2e-11 Identities = 87/319 (27%), Positives = 137/319 (42%), Gaps = 68/319 (21%) Query: 378 YDVAIIDEATQST---IPSILIPLNKVERFVLAGDHKQLPPTILSLEAQ----------- 423 +D IIDEA+Q T + I++ NK FVL GD KQLP I E + Sbjct: 806 FDQLIIDEASQLTEADLAGIVVLFNK---FVLIGDQKQLPAVITQNEEECRVEVEPFRRY 862 Query: 424 -----ELSRTLFEGLIERYPWKS-----EMLVVQYRMNERIMEFPSKEFYGGKIIADESV 473 +L +LFE LI K L YRM+ I + + + + Sbjct: 863 AINISDLRISLFERLINNAKNKGWNHCYGQLTEHYRMHRDIASLIAHHYDRPLVEQTQEQ 922 Query: 474 RGITLRDLVEYQSPNDSWGKILNPENVIVFIDTSKAENKWERQRRGSESRENPLEAEIVA 533 R I + + ND K+ + + E S R+N EA I A Sbjct: 923 RKI---ESSYENNDNDLLSKLSKSRTIFI-----------ETPSETSIQRKNTNEAIIAA 968 Query: 534 KIV-----DKLLSIGVKPEWIGVITPYDDQRDLISMKVP----------EDVEVKTVDGY 578 IV +KLL + IG+I P+ Q I+ ++ + + V TV+ + Sbjct: 969 TIVKTYWENKLLPMAE----IGIIAPFRAQVAEINQQLEKIFAGADFSRDSIVVDTVERF 1024 Query: 579 QGREKEVIILS--LVRSNKLGEIGFLKDL------RRLNVSLTRAKRKLIVVGDSSTLSS 630 QG E+E+II S + S ++ I + D R+L VS++RAK KL+++G+SS L Sbjct: 1025 QGDERELIIFSTTISWSKQVKNIQSIADGDRQGTDRKLLVSISRAKSKLVILGNSSQLQF 1084 Query: 631 HETYKKMIEFFKEKGCFIE 649 Y+++I+ ++ I+ Sbjct: 1085 APAYRELIKHIEQSNGLID 1103 >dbj|BAB14299.1| (AK022902) unnamed protein product [Homo sapiens] Length = 324 Score = 71.8 bits (173), Expect = 2e-11 Identities = 34/80 (42%), Positives = 57/80 (70%), Gaps = 1/80 (1%) Query: 571 EVKTVDGYQGREKEVIILSLVRSNKL-GEIGFLKDLRRLNVSLTRAKRKLIVVGDSSTLS 629 EV TVD +QGR+K+ +I++ VR+N + G IGFL L+RLNV++TRAK L ++G TL Sbjct: 17 EVDTVDAFQGRQKDCVIVTCVRANSIQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLM 76 Query: 630 SHETYKKMIEFFKEKGCFIE 649 ++ + ++I+ +++G I+ Sbjct: 77 ENQHWNQLIQDAQKRGAIIK 96 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.318 0.137 0.381 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 223438808 Number of Sequences: 2977 Number of extensions: 9185145 Number of successful extensions: 30231 Number of sequences better than 1.0e-10: 98 Number of HSP's better than 0.0 without gapping: 38 Number of HSP's successfully gapped in prelim test: 60 Number of HSP's that attempted gapping in prelim test: 29766 Number of HSP's gapped (non-prelim): 166 length of query: 653 length of database: 189,106,746 effective HSP length: 61 effective length of query: 592 effective length of database: 152,599,039 effective search space: 90338631088 effective search space used: 90338631088 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.7 bits) S2: 168 (69.9 bits)