BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1643 (codB-like) DE:PURINE-CYTOSINE PERMEASE related
         (414 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||F75087 purine-cytosine permease related PAB1643 - Pyrococcu...   823  0.0
pir||A71058 probable cytosine permease - Pyrococcus horikoshii >...   757  0.0
pir||G82032 probable permease NMA0365 [imported] - Neisseria men...   226  3e-58
pir||G81010 conserved hypothetical protein NMB2067 [imported] - ...   220  2e-56
dbj|BAB05601.1| (AP001513) cytosine permease [Bacillus halodurans]    150  4e-35
pir||H83009 probable transporter PA5099 [imported] - Pseudomonas...   122  1e-26
pir||B83591 probable transporter PA0443 [imported] - Pseudomonas...   120  4e-26
pir||E83590 cytosine permease PA0438 [imported] - Pseudomonas ae...   119  5e-26
emb|CAC11736.1| (AL445064) purine-cytosine permease related prot...   118  2e-25
pir||E70081 purine-cytosine permease homolog yxlA - Bacillus sub...   110  3e-23
sp|P25525|CODB_ECOLI CYTOSINE PERMEASE >gi|78382|pir||S22661 cyt...   109  6e-23
pir||E42594 hypothetical protein ORF5 hyuC 3'-region, hyuE 5'-re...   108  1e-22
gb|AAK41877.1| Cytosine permease (codB) [Sulfolobus solfataricus]     106  5e-22
pir||A83387 probable transporter (membrane subunit) PA2073 [impo...   106  7e-22
pir||T35663 probable transmembrane protein - Streptomyces coelic...   103  3e-21
gb|AAG02128.1|AF146701_4 (AF146701) permease homolog HyuP [Arthr...    99  1e-19
sp|P94575|YWOE_BACSU HYPOTHETICAL 54.0 KD PROTEIN IN NRGA-USD IN...    83  7e-15
gi|6320902 purine-cytosine permease; Fcy21p [Saccharomyces cerev...    77  3e-13
pir||T28687 hypothetical protein - Streptomyces coelicolor >gi|3...    77  4e-13
gb|AAG02126.1|AF146701_2 (AF146701) transport protein homolog [A...    77  4e-13
pir||S50563 hypothetical protein YER060w - yeast (Saccharomyces ...    76  5e-13
sp|Q01266|YHYC_PSESN HYPOTHETICAL PROTEIN IN HYUC 3'REGION (ORF ...    76  7e-13
emb|CAC12338.1| (AL445066) purine-cytosine permease related prot...    76  7e-13
pir||T48383 uracil transporter-like protein - Arabidopsis thalia...    76  9e-13
gb|AAA25848.1| (M72717) ORF 5 [Pseudomonas sp.]                        75  1e-12
sp|P75712|ALLP_ECOLI PUTATIVE ALLANTOIN PERMEASE (ALLANTOIN TRAN...    72  1e-11
emb|CAA36040.1| (X51751) cytosine-purine permease (AA 1-533) [Sa...    72  1e-11
gi|6320897 purine-cytosine permease; Fcy2p [Saccharomyces cerevi...    70  4e-11

>pir||F75087 purine-cytosine permease related PAB1643 - Pyrococcus abyssi
           (strain Orsay) >gi|5458515|emb|CAB50003.1| (AJ248286)
           PURINE-CYTOSINE PERMEASE related [Pyrococcus abyssi]
           Length = 414
           
 Score =  823 bits (2103), Expect = 0.0
 Identities = 414/414 (100%), Positives = 414/414 (100%)

Query: 1   MEEIKPVKEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAV 60
           MEEIKPVKEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAV
Sbjct: 1   MEEIKPVKEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAV 60

Query: 61  MSLIAIEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPG 120
           MSLIAIEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPG
Sbjct: 61  MSLIAIEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPG 120

Query: 121 TYYAWVIVLGILVTAWTIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPG 180
           TYYAWVIVLGILVTAWTIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPG
Sbjct: 121 TYYAWVIVLGILVTAWTIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPG 180

Query: 181 TGGLSLLIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFLGALSN 240
           TGGLSLLIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFLGALSN
Sbjct: 181 TGGLSLLIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFLGALSN 240

Query: 241 VAMGKEDPISLIAAYGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVLLV 300
           VAMGKEDPISLIAAYGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVLLV
Sbjct: 241 VAMGKEDPISLIAAYGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVLLV 300

Query: 301 GTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADESIRAPG 360
           GTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADESIRAPG
Sbjct: 301 GTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADESIRAPG 360

Query: 361 IIAWVIGFILYLSLTMESLIGISVPVLSQIGNEIGASIPVFLITMVLYYILSRR 414
           IIAWVIGFILYLSLTMESLIGISVPVLSQIGNEIGASIPVFLITMVLYYILSRR
Sbjct: 361 IIAWVIGFILYLSLTMESLIGISVPVLSQIGNEIGASIPVFLITMVLYYILSRR 414


>pir||A71058 probable cytosine permease - Pyrococcus horikoshii
           >gi|3257576|dbj|BAA30259.1| (AP000005) 422aa long
           hypothetical cytosine permease [Pyrococcus horikoshii]
           Length = 422
           
 Score =  757 bits (1933), Expect = 0.0
 Identities = 364/412 (88%), Positives = 397/412 (96%)

Query: 1   MEEIKPVKEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAV 60
           M++IKPVKE+IFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLK+ALAIIILGHLLGNAV
Sbjct: 1   MQDIKPVKERIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKQALAIIILGHLLGNAV 60

Query: 61  MSLIAIEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPG 120
           MSLIAIEGQETGLPTMVLSRGPLGGKGS+LPS LNYLQLIGWTAIMLIVGARALDVIFPG
Sbjct: 61  MSLIAIEGQETGLPTMVLSRGPLGGKGSILPSLLNYLQLIGWTAIMLIVGARALDVIFPG 120

Query: 121 TYYAWVIVLGILVTAWTIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPG 180
           TY+AWVIVLG+LVT WT+VGPERW WLEKLSV+LL +LS WLLYVIFSKYSFSELWNKPG
Sbjct: 121 TYFAWVIVLGVLVTVWTLVGPERWGWLEKLSVILLAILSGWLLYVIFSKYSFSELWNKPG 180

Query: 181 TGGLSLLIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFLGALSN 240
           TGGL LLIALDLVIAMPLSWAPTIADYSRFAKS++DAAWGTYLGHL GSAFCYFLGALSN
Sbjct: 181 TGGLPLLIALDLVIAMPLSWAPTIADYSRFAKSKSDAAWGTYLGHLAGSAFCYFLGALSN 240

Query: 241 VAMGKEDPISLIAAYGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVLLV 300
           VAMGKEDPISLIAAYGLGIPAMLIVL+STLNTTFMDIYSASITWKN+NPKA+LKTQ+L+V
Sbjct: 241 VAMGKEDPISLIAAYGLGIPAMLIVLVSTLNTTFMDIYSASITWKNVNPKASLKTQILIV 300

Query: 301 GTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADESIRAPG 360
           GTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMI DYF+V+++YDA +LLA++ IR PG
Sbjct: 301 GTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMIADYFMVRKKYDANELLANQRIRIPG 360

Query: 361 IIAWVIGFILYLSLTMESLIGISVPVLSQIGNEIGASIPVFLITMVLYYILS 412
           I+AW++GF LY+S+TMESLIG+ VPVLS +G+ IGASIPVFLIT+VLYYILS
Sbjct: 361 IVAWIVGFALYISMTMESLIGVPVPVLSPLGDRIGASIPVFLITLVLYYILS 412


>pir||G82032 probable permease NMA0365 [imported] - Neisseria meningitidis
           (group A strain Z2491) >gi|7379117|emb|CAB83666.1|
           (AL162752) putative permease [Neisseria meningitidis
           Z2491]
           Length = 437
           
 Score =  226 bits (571), Expect = 3e-58
 Identities = 138/379 (36%), Positives = 205/379 (53%), Gaps = 18/379 (4%)

Query: 20  IWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTMVLS 79
           IWFGA   IA I  G LL P L  +  LA ++LGH +G A+    A  G  TG  +M   
Sbjct: 17  IWFGAAVSIAEISTGTLLAP-LGWQRGLAALLLGHAVGGALFFAAAYIGALTGRSSMESV 75

Query: 80  RGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALD----VIFPGTYYAW-VIVLGILVT 134
           R   G +GSVL S  N LQL GWTA+M+  GA        V++ G  + W  +  G L+ 
Sbjct: 76  RLSFGKRGSVLFSVANMLQLAGWTAVMIYAGATVSSALGKVLWDGESFVWWALANGALIV 135

Query: 135 AWTIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPGTGGLSLLIALDLVI 194
            W + G  +   L+ +S++L+ +  +WL   +FS    +       + G+S   A++L  
Sbjct: 136 LWLVFGARKTGGLKTVSMLLMLLAVLWLSAEVFSTAGSTAA---QVSDGMSFGTAVELSA 192

Query: 195 AMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFLGALSNVAMGKEDPISLIAA 254
            MPLSW P  ADY+R A+    A     L + +   + Y LG  + +  G+ D   ++  
Sbjct: 193 VMPLSWLPLAADYTRHARRPFAATLTATLAYTLTGCWMYALGLAAALFTGETDVAKILLG 252

Query: 255 YGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVLLVGTLGTLLALVFPVD 314
            GLG   +L V++ST+ TTF+D YSA ++  NI+ K +     + V  +GTLLA++ PV 
Sbjct: 253 AGLGAAGILAVVLSTVTTTFLDAYSAGVSANNISAKLSEIPIAVAVAVVGTLLAVLLPVT 312

Query: 315 KYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADESIRAPGIIAWVIGFILY--- 371
           +YE FLLLIG  F P+AA++I D+F++KR  +       E     G++ W+ GFILY   
Sbjct: 313 EYENFLLLIGSVFAPMAAVLIADFFVLKRREEI------EGFDFAGLVLWLAGFILYRFL 366

Query: 372 LSLTMESLIGISVPVLSQI 390
           LS   ES IG++ PV+S +
Sbjct: 367 LSSGWESSIGLTAPVMSAV 385


>pir||G81010 conserved hypothetical protein NMB2067 [imported] - Neisseria
           meningitidis (group B strain MD58)
           >gi|7227329|gb|AAF42386.1| (AE002556) conserved
           hypothetical protein [Neisseria meningitidis MC58]
           Length = 407
           
 Score =  220 bits (555), Expect = 2e-56
 Identities = 136/379 (35%), Positives = 203/379 (52%), Gaps = 18/379 (4%)

Query: 20  IWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTMVLS 79
           IWFGA   IA I  G LL P L  +  LA ++LGH +G A+    A  G  TG  +M   
Sbjct: 17  IWFGAAVSIAEISTGTLLAP-LGWQRGLAALLLGHAVGGALFFAAAYIGALTGRSSMESV 75

Query: 80  RGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALD----VIFPGTYYAW-VIVLGILVT 134
           R   G +GSVL S  N LQL GWTA+M+  GA        V++ G  + W  +  G L+ 
Sbjct: 76  RLSFGKRGSVLFSVANMLQLAGWTAVMIYAGATVSSALGKVLWDGESFVWWALANGALIV 135

Query: 135 AWTIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPGTGGLSLLIALDLVI 194
            W + G  +   L+ +S++L+ +  +WL   +FS    +       + G+S   A++L  
Sbjct: 136 LWLVFGARKTGGLKTVSMLLMLLAVLWLSAEVFSTAGSTAA---QVSDGMSFGTAVELSA 192

Query: 195 AMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFLGALSNVAMGKEDPISLIAA 254
            MPLSW P  ADY+R A+    A     L + +   + Y LG  + +  G+ D   ++  
Sbjct: 193 VMPLSWLPLAADYTRHARRPFAATLTATLAYTLTGCWMYALGLAAALFTGETDVAKILLG 252

Query: 255 YGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVLLVGTLGTLLALVFPVD 314
            GLG   +L V++ST+ TTF+D YSA  +  NI+ +       + V  +GT+LA++ PV 
Sbjct: 253 AGLGAAGILAVVLSTVTTTFLDAYSAGASANNISARFAETPVAVGVTLIGTVLAVMLPVT 312

Query: 315 KYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADESIRAPGIIAWVIGFILY--- 371
           +YE FLLLIG  F P+AA++I D+F++KR  +       E     G++ W+ GFILY   
Sbjct: 313 EYENFLLLIGSVFAPMAAVLIADFFVLKRREEI------EGFDFAGLVLWLAGFILYRFL 366

Query: 372 LSLTMESLIGISVPVLSQI 390
           LS   ES IG++ PV+S +
Sbjct: 367 LSSGWESSIGLTAPVMSAV 385


>dbj|BAB05601.1| (AP001513) cytosine permease [Bacillus halodurans]
           Length = 445
           
 Score =  150 bits (374), Expect = 4e-35
 Identities = 112/385 (29%), Positives = 190/385 (49%), Gaps = 16/385 (4%)

Query: 3   EIKPVKEKIFDFWSNFS-IWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVM 61
           E  PV E+    W + S +W G    ++    G  L   L+L +A+   +LG L+ + V 
Sbjct: 14  ERMPVPEEHRKGWIHLSLVWLGIAIALSATVLGGTLGGGLTLGQAILATMLGALVLSIVS 73

Query: 62  SLIAIEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPGT 121
           +  ++ G  TGL T ++S+  LG  G+ + S +  + L GW  + L +   +   +    
Sbjct: 74  ACCSVVGARTGLSTGLVSKFALGTYGAYVVSAVIAIALFGWFGVQLDLFGTSFQQVIMNV 133

Query: 122 Y------YAWVIVLGILVTAWTIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSEL 175
           +         VI+ GIL+T+  ++G +    L K +V L+G+L +  L+ + S   +S++
Sbjct: 134 FGLNIPKILLVIIGGILMTSTAVIGYKAIEKLSKAAVPLMGLLLIASLWRVLSSQQWSDV 193

Query: 176 WNKPGTGG-LSLLIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYF 234
            N P TG  L L IA+ LVI      A    D +R+AK+  DA  G++ G LVG +    
Sbjct: 194 VNAPMTGDPLPLGIAISLVIGSFAVGAVIGPDIARYAKTPKDAVIGSFSGFLVGFSAVLI 253

Query: 235 LGALSNVAMGKEDPISLIAAYGLGIPAMLIVLISTLNTTFMDIYSA----SITWKNINPK 290
           + A+   A G+ D ++++   G G  AMLI++++   T   ++YSA    S+ +K+I PK
Sbjct: 254 VAAILAKATGEVDIVAIMLGLGWGTFAMLILILAQWTTNDNNLYSAALGFSVIFKSI-PK 312

Query: 291 ANLKTQVLLVGTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKL 350
           A L    +  G +GTL+A+    D +  FL+ +     P+  I + DY L K +Y    L
Sbjct: 313 AKL---TIGAGIIGTLMAVFGIYDNFIPFLIFLSALIPPIGGIYVADYLLNKGKYSFANL 369

Query: 351 LADESIRAPGIIAWVIGFILYLSLT 375
              + I   G+  W+I  +     T
Sbjct: 370 SNMKMINPIGVTTWMIASLFAFMTT 394


>pir||H83009 probable transporter PA5099 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9951394|gb|AAG08484.1|AE004922_9
           (AE004922) probable transporter [Pseudomonas aeruginosa]
           Length = 480
           
 Score =  122 bits (302), Expect = 1e-26
 Identities = 113/438 (25%), Positives = 205/438 (46%), Gaps = 32/438 (7%)

Query: 6   PVKEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLS-LKEALAIIILGHLLGNAVMSLI 64
           P  E+    +S F++W GA+  I  I  GAL       +  +L  ++LG LLG AVM+L 
Sbjct: 20  PANERHGRLYSQFTLWLGANLQITAIVTGALAVVLGGDVFWSLVGLLLGQLLGGAVMALH 79

Query: 65  AIEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPGTYYA 124
           A +G   GLP M+ SR   G  G+ +P  L  L  +G+TA   ++  +A+  +   +  A
Sbjct: 80  AAQGPRLGLPQMISSRVQFGVYGACIPIALVCLMYLGFTATGTVLSGQAIGQLTGLSDSA 139

Query: 125 WVIVLGILVTAWTIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPGTGGL 184
            + +    +   T++G      + +++ VL  +   +L   +       +L         
Sbjct: 140 GIFIFAAFIVLVTVLGYRVIHIIGRIASVLGIIAFAYLFSRLMLLSDIGDLLAIRHFSWA 199

Query: 185 SLLIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTY----LGHLVGSAFCYFLG---- 236
           S L+A+ L  +  +++ P +ADYSR+  + + ++W T+    LG ++G+     LG    
Sbjct: 200 SFLLAVSLAASWQIAFGPYVADYSRYLPA-STSSWKTFLAVGLGSVLGAQASMVLGVFSA 258

Query: 237 ALSNVAMGKEDPISLIAAYGLGIPAMLI--------VLISTLNT--TFMDIYS--ASITW 284
           AL+N      +   ++     G  A L+        V ISTLN+  +FM I +  +S+  
Sbjct: 259 ALANGQFAGREVAYIVGLGSSGTVAALLYFSIAFGKVTISTLNSYGSFMCIATIISSVRG 318

Query: 285 KNINPKANLKTQVLLVGTLGTLLALVFP---VDKYEAFLLLIGGAFVPLAAIMITDYFLV 341
           +    +      VL +    TL+AL+     +  +++F+L +   F P +A+ + DY+ +
Sbjct: 319 QLEITRVQRLFFVLAIVGASTLIALLGQHSFLAAFKSFILFLLTFFTPWSAVNLVDYYFI 378

Query: 342 KREYDAEKLLADESIR-----APGIIAWVIGFILYLSLTMESLIGISVPVLSQIGNEIGA 396
            RE      LAD   R      PGI  + +G ++ +     +L   + P++  +G    +
Sbjct: 379 TRERYDVPALADPDGRYGRWNLPGIAVYTLGVLVQMPFLATTL--YTGPMVEHLGGVDIS 436

Query: 397 SIPVFLITMVLYYILSRR 414
            I   L+  VLYY+++RR
Sbjct: 437 WIIGLLVPAVLYYLVARR 454


>pir||B83591 probable transporter PA0443 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9946301|gb|AAG03832.1|AE004481_8
           (AE004481) probable transporter [Pseudomonas aeruginosa]
           Length = 496
           
 Score =  120 bits (297), Expect = 4e-26
 Identities = 115/411 (27%), Positives = 186/411 (44%), Gaps = 55/411 (13%)

Query: 7   VKEKIFDFWSNFSIWFGADFGIAVIWAGALLTPY--LSLKEALAIIILGHLLGNAVMSLI 64
           V+++ ++ W   ++W G    +     G +LT Y  LS+ EAL  I+L +L+    ++L 
Sbjct: 38  VEQRTWNRWHITALWIGMSICVPTYTLGGVLTAYFGLSVGEALLAILLANLVVLIPLTLN 97

Query: 65  AIEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPGTYYA 124
           A  G   G+P  VL R   G  GS +P  +  +   GW  I  + G  A+ +     + A
Sbjct: 98  AFAGTRYGIPFPVLLRASFGIIGSNVPCLIRAVVACGWFGIQTLFGGLAIHLFLGSIFPA 157

Query: 125 WVI------VLGIL----VTAWTIV-GPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFS 173
           W        V+G L    +  W ++ G E  +WLE LS  LL ++ + LL       S S
Sbjct: 158 WKALGGTGEVIGFLLFWGLNLWVVLRGAESIKWLETLSAPLLVLVGLGLLVWALPHISVS 217

Query: 174 ELWNKP--GTGGLSL----LIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLV 227
           EL  +P     G S+    +  L  ++    + +  I D+SR+A+S+ D      LG + 
Sbjct: 218 ELLAQPPKRPEGASVTGYFMAGLTAMVGFWATLSLNIPDFSRYARSQKD----QILGQIF 273

Query: 228 GSAFCYFLGALSNVAMGK----------EDPISLIA---AYGLGIPAMLIVLISTLNT-T 273
           G     FL A   V M             DP+SLI    + G    AM +++++TL+T T
Sbjct: 274 GLPLTMFLFAALGVVMTAASASLVGETVSDPVSLIGHIPSPGWVAVAMALIIVATLSTNT 333

Query: 274 FMDIYSASITWKNINPKANLKTQVL--------------LVGTLGTLLALVFPVDKYEAF 319
             +I S +  ++NI PK   +T+ +              L+  LG +++ +     Y  +
Sbjct: 334 AANIVSPTNDFQNIAPKLIGRTRAVWLTGFIGLALMAHELLKKLGWIVSDLSLESVYSNW 393

Query: 320 LLLIGGAFVPLAAIMITDYFLVKRE-YDAEKLLADESIRA---PGIIAWVI 366
           LL       P+A IM+ DYFLV+R+  D   L  D+   A   PG  A+ +
Sbjct: 394 LLGYSSLLGPIAGIMVVDYFLVRRQRLDLAGLYRDDVYPAWNWPGFAAFAV 444


>pir||E83590 cytosine permease PA0438 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9946296|gb|AAG03827.1|AE004481_3
           (AE004481) cytosine permease [Pseudomonas aeruginosa]
           Length = 416
           
 Score =  119 bits (296), Expect = 5e-26
 Identities = 104/397 (26%), Positives = 176/397 (44%), Gaps = 29/397 (7%)

Query: 20  IWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTMVLS 79
           +  G  F  A +W G  L   LS  +    ++LG+L+     +++   G  TGL T +L+
Sbjct: 26  VMLGLTFFSASMWTGGTLGTGLSYDDFFLAVLLGNLMLGLYTAILGFIGARTGLSTHLLA 85

Query: 80  RGPLGGKGSVLPSFLNYLQLIGWTAIML------IVGARALDVIFPGTYYAWVIVLGILV 133
               G KGS LPS L     +GW  + +      +  A  LDV         ++V G L+
Sbjct: 86  HYSFGSKGSWLPSALLGGTQVGWFGVGVAMFAIPVAKATGLDVNL------LILVSGALM 139

Query: 134 TAWTIVGPERWRWLEKLSV---VLLGVLSVWLLYVIFSKYSFSELWNKPGTGGLSLLIAL 190
           T     G      L  ++V   V+LG  SVWL   +      + L     +  LSL  A+
Sbjct: 140 TLTVFFGIAGLTLLSAIAVPAIVVLGSYSVWL--AVRDAGGLAALQQVTPSAPLSLSTAI 197

Query: 191 DLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFLGALSNVAMGKEDPIS 250
            LV+   +S     AD+ RF +S   A     +   +G++  +  GA    A+GK D   
Sbjct: 198 ALVVGSFVSAGTLTADFVRFGRSARTAVVVCLVAFFLGNSLMFIFGAAGAAAVGKSDISD 257

Query: 251 LIAAYGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVLLVGTLGTLLALV 310
           ++ A GL IPA+L++ ++   T    +Y++ + + NI   ++ +   +L G LGTL AL 
Sbjct: 258 VMIAQGLLIPAILVLGLNIWTTNDNALYASGLGFANITGLSS-RFLAMLNGALGTLAAL- 315

Query: 311 FPVDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADESIRAPGIIAWVIGFIL 370
           +  + +  +L  +  A  P+  ++I DY   +R Y        ++I    I+A   G   
Sbjct: 316 WLYNHFVGWLTFLSAAIPPIGGVIIADYLSRRRRYRQHPCADIQAINWAAILAVACG--- 372

Query: 371 YLSLTMESLIGISVPVLSQIGNEIGASIPVFLITMVL 407
                  +  G  +P +  +   +GA+I   L+  +L
Sbjct: 373 -------TAAGHWLPGIVPVNAVLGAAIAYLLLNPLL 402


>emb|CAC11736.1| (AL445064) purine-cytosine permease related protein [Thermoplasma
           acidophilum]
           Length = 460
           
 Score =  118 bits (292), Expect = 2e-25
 Identities = 104/420 (24%), Positives = 192/420 (44%), Gaps = 32/420 (7%)

Query: 16  SNFSIWFGADFGIAVIWAGALLTPYLSLKEALAIIIL--GHLLGNAVMSLIAIEGQETGL 73
           S F IWF ++  +     G  +  YL L    +I+ +  G + G  +++ ++  G    +
Sbjct: 37  SMFYIWFASNLTVGDFAVG-FIPVYLGLPILYSIVAIAVGTIAGGIMLAYMSQLGAVYRV 95

Query: 74  PTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPGTYYAWVIVLGILV 133
           P M + R P G  G  L S L +    GW  + +I+ + A+  +    YYA V+++  +V
Sbjct: 96  PQMYMGRAPFGTVGGSLLSILQWGNTAGWLTVNVILASLAIYQMVKIPYYAIVLLIVAIV 155

Query: 134 TAWTIVGPERWRWLEKLSVVLLGVLSVWL-LYVIFS----KYSFSELWNKPGTGGLSLLI 188
               +VG    R LE+    +LG+L V+L L++I S     Y + + ++ P   G++   
Sbjct: 156 ALTALVGYRAIRILERSMSYVLGLLFVFLVLFLIHSHASISYQYVDSFSIPAAFGITFAS 215

Query: 189 ALDLVIAMPLSWAPTIADYSRFAKSRADAA---WGTYLGHLVGSAFCYFLGALSNVAMGK 245
           A   +    +SW P  ADYSR   S   +    + T LG ++ S F   +G + + A G 
Sbjct: 216 AFSYI----MSWGPYAADYSRHVSSSKPSKSIFYYTLLGSVIASVFAEIVGLMVSAASGN 271

Query: 246 ------EDPISLIAAYGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVLL 299
                  D  +++  Y   +  ++ + +  ++   +++YS S+ + +I  KA+    + +
Sbjct: 272 PSGSPAADLANVMNKY--AVIGLIALFLGGISANAINLYSNSLAFLSIGFKAHRWVAIAV 329

Query: 300 VGTLGTLLALV---FPVDKYEAFLLLIGGAFVPLAAIMITDYFLVK--REYDAEKLLADE 354
                 LL ++        YE FL ++     P   IMI  +F++K  R  + E L    
Sbjct: 330 ASVFSLLLGIIGFFRFYGFYETFLFILDYWITPWIGIMIAHFFILKRLRHQEFEDL---P 386

Query: 355 SIRAPGIIAWVIGFILYLSLTMESLIGISVPVLSQIGNEIGASIPVFLITMVLYYILSRR 414
            I  PGI A++I   + +     + I I++P+ S +     +    F   M++Y  LSR+
Sbjct: 387 KIVKPGIYAYIISIAVSIPFMSPAGI-INMPLASMLHGVDISYFVSFFSAMIIYLYLSRK 445


>pir||E70081 purine-cytosine permease homolog yxlA - Bacillus subtilis
           >gi|1783255|dbj|BAA11732.1| (D83026) homologous to
           purine-cytosine permease (SwissProt:FCY2_YEAST);
           hypothetical [Bacillus subtilis]
           >gi|2636406|emb|CAB15897.1| (Z99123) similar to
           purine-cytosine permease [Bacillus subtilis]
           Length = 457
           
 Score =  110 bits (273), Expect = 3e-23
 Identities = 113/423 (26%), Positives = 187/423 (43%), Gaps = 32/423 (7%)

Query: 18  FSIWFGADFGIAVIWAGAL-LTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTM 76
           F +WFGA+  I  +  G + +   L+L  ++A II G L+G   M+  + +G + G+P M
Sbjct: 24  FPVWFGANMHITTLVTGTIPVAMGLNLFWSVAAIICGTLIGAIFMASHSAQGPQLGIPQM 83

Query: 77  VLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALD--VIFPGTYYAWVIVLGILVT 134
           + SR   G  G++LP FL     +G+ A   I+ A  L   V  PG++   +I L  +  
Sbjct: 84  IQSRAQFGVIGAILPLFLVMFIYLGFFASSTILAAGTLSSFVPIPGSWS--IIGLSAVCF 141

Query: 135 AWTIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPGTGGLSL-LIALDLV 193
             TI G +    ++K+       +      +IF     +  W  PG   L + L+A+  V
Sbjct: 142 LLTIFGHDLIHKMQKILSWTSFAVFFAATILIFQLPIPAGSW-IPGAIDLPIFLVAVSAV 200

Query: 194 IAMPLSWAPTIADYSRFAKSRADAA---WGTYLGHLVGSAFCYFLGALSNVAM---GKED 247
               L++AP +ADYSR+   +  A+   W +Y G  V S +   LGAL   ++       
Sbjct: 201 ATWQLAYAPYVADYSRYLPVKTPASKTFWYSYAGTSVSSIWMMLLGALLTTSLPDFTANS 260

Query: 248 PISLIAAYG-LGIPAMLIVLISTLNTTFMDIYSASI-TWKNINPKANLKTQ--------- 296
              ++  +G      ++IVL   +     ++Y A + T   + P   LK           
Sbjct: 261 GSQIVQLFGPFSFIMLIIVLFGQMAINVFNLYGAFMSTTTTLEPFLKLKVTPKVRIIMIL 320

Query: 297 -VLLVGTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADES 355
            V LVGT+ +LL     ++ +  F+  I    +P  AI + DY+ V+      K + D  
Sbjct: 321 GVTLVGTVLSLLGQSNFMELFLNFIFFISYFLIPWTAINLVDYYFVRHGKYQVKAMFD-- 378

Query: 356 IRAP-GIIAWVIGFILYLSLTME-SLIGISV---PVLSQIGNEIGASIPVFLITMVLYYI 410
           +  P G + W+      LS+ +E   I  S    P+    G    A I    +  VLYY+
Sbjct: 379 VNGPYGKVNWITTIAFVLSILLEIPFINTSFYIGPLAKMFGGGDIAWIIGLAVPSVLYYV 438

Query: 411 LSR 413
           L +
Sbjct: 439 LMK 441


>sp|P25525|CODB_ECOLI CYTOSINE PERMEASE >gi|78382|pir||S22661 cytosine transport protein
           - Escherichia coli >gi|581051|emb|CAA45195.1| (X63656)
           cytosine permease [Escherichia coli]
           >gi|1657532|gb|AAB18060.1| (U73857) cytosine permease
           [Escherichia coli] >gi|1786530|gb|AAC73439.1| (AE000140)
           cytosine permease/transport [Escherichia coli K12]
           >gi|1586752|prf||2204355A cytosine permease [Escherichia
           coli]
           Length = 419
           
 Score =  109 bits (270), Expect = 6e-23
 Identities = 89/351 (25%), Positives = 157/351 (44%), Gaps = 7/351 (1%)

Query: 20  IWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTMVLS 79
           +  G  F  A +W G  L   LS  +    +++G+LL     S +   G +TGL T +L+
Sbjct: 26  VMLGLTFFSASMWTGGTLGTGLSYHDFFLAVLIGNLLLGIYTSFLGYIGAKTGLTTHLLA 85

Query: 80  RGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPGTYYAWVIVLGILVTAWTIV 139
           R   G KGS LPS L     +GW  + + + A  +           + V G+L+T     
Sbjct: 86  RFSFGVKGSWLPSLLLGGTQVGWFGVGVAMFAIPVGKATGLDINLLIAVSGLLMTVTVFF 145

Query: 140 GPERWRWLEKLSV---VLLGVLSVWLLYVIFSKYSFSELWNKPGTGGLSLLIALDLVIAM 196
           G      L  ++V     LG  SVWL   +        L        L   +AL LV+  
Sbjct: 146 GISALTVLSVIAVPAIACLGGYSVWL--AVNGMGGLDALKAVVPAQPLDFNVALALVVGS 203

Query: 197 PLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFLGALSNVAMGKEDPISLIAAYG 256
            +S     AD+ RF ++   A     +   +G++  +  GA    A+G  D   ++ A G
Sbjct: 204 FISAGTLTADFVRFGRNAKLAVLVAMVAFFLGNSLMFIFGAAGAAALGMADISDVMIAQG 263

Query: 257 LGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVLLVGTLGTLLALVFPVDKY 316
           L +PA++++ ++   T    +Y++ + + NI   ++ KT  ++ G +GT+ AL +  + +
Sbjct: 264 LLLPAIVVLGLNIWTTNDNALYASGLGFANITGMSS-KTLSVINGIIGTVCAL-WLYNNF 321

Query: 317 EAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADESIRAPGIIAWVIG 367
             +L  +  A  P+  ++I DY + +R Y+        S+    I+A  +G
Sbjct: 322 VGWLTFLSAAIPPVGGVIIADYLMNRRRYEHFATTRMMSVNWVAILAVALG 372


>pir||E42594 hypothetical protein ORF5 hyuC 3'-region, hyuE 5'-region -
           Pseudomonas sp. plasmid pHN671
           Length = 456
           
 Score =  108 bits (267), Expect = 1e-22
 Identities = 106/443 (23%), Positives = 199/443 (43%), Gaps = 57/443 (12%)

Query: 8   KEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIE 67
           KE+     + F +W G    +      A L P LS  + +   ILG+L+   +++L+   
Sbjct: 6   KERNMSSIAYFILWVGIAVQLVTPITAAQLYPALSPLQIIIACILGNLIVAILLTLLGDI 65

Query: 68  GQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFP-----GTY 122
           G   G+P  V  R   G  G+ +P  +  +  + W      +GA ALD I          
Sbjct: 66  GVRYGIPYAVYIRASFGYLGAHIPGIVRAVPAVFWFGFQTWMGAYALDAIMEMLTGYSNL 125

Query: 123 YAWVIVLGILVTAWTIVGPE---RWRWLEKLSVVLLGVLSVWLLYVIFSKY-SFSELWNK 178
              +I+ G++    T +G E   ++ WL   S++++G+  +  +Y++   + +FSE+++ 
Sbjct: 126 TLLIILFGVVQIINTAMGMEAITKFEWLASPSILIIGI--ILQVYIMKQHHLTFSEIFSH 183

Query: 179 PGTGGLSLLIALDLVIAMPLSWAPTIADYSRFAKSRADAA---W-----GTYLGH---LV 227
            G GG+S+  A+ +++   ++ A    D++RF K++  ++   W     G++  H   L+
Sbjct: 184 GGDGGVSMGYAVVVMMGTYITMALNAPDFTRFLKTKTGSSEPNWWKVNKGSFWAHTFGLI 243

Query: 228 GSAFCY-FLGALSNVAMGKEDPI-SLIAAYGLGIPAMLIVLISTLNTTFMDIYSASITWK 285
           GS   +  +G  S VA G  +PI ++I   G   P +LIV ++ +    +  +S +I+  
Sbjct: 244 GSMLLFTIIGLTSGVATGTWNPIDAMIQTMGKDNPFLLIVCLAFV---ILAQWSTNISAN 300

Query: 286 NINP----------KANLKTQVLLVGTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMI 335
            + P          K +     ++ G +G L+      +     L++I     P+  IM 
Sbjct: 301 LLPPGYIIVNLFPRKISFPMGAIIAGIIGLLIQPWNYAEFVPQILMVITATLAPIVGIMF 360

Query: 336 TDYFLVKREYDAEKLLADESIRAPGIIAW-----VIGFILYLSLTMESLIGISVPVLSQI 390
           TDY+L+++     +L  DE  +  G   +         I Y+        G+SV +    
Sbjct: 361 TDYYLLRK----RRLNLDELYKVDGQYKYWKNVNPAAIIAYIP------SGLSVLLFPDY 410

Query: 391 GNEIGASIPVFLITMVLYYILSR 413
           G      +   LI+MVLYY L +
Sbjct: 411 G-----FVTALLISMVLYYTLMK 428


>gb|AAK41877.1| Cytosine permease (codB) [Sulfolobus solfataricus]
           Length = 453
           
 Score =  106 bits (262), Expect = 5e-22
 Identities = 100/421 (23%), Positives = 184/421 (42%), Gaps = 25/421 (5%)

Query: 8   KEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIE 67
           K+  + F++ F ++      IAVIWAG  L   L+  +A+  ++ G ++   + SL A  
Sbjct: 21  KDSRYGFFNVFLVFSSVYGAIAVIWAGGALGYGLTFSQAIIAVLSGTVVLGILGSLTAAV 80

Query: 68  GQETGLPTMVLSRGPLGGKGSVLPSFL--NYLQLIGWTAIMLIVGARALDVIFPGTYYAW 125
           G  +GL T V+ R PLG  G  +   L       IGW A+   +    +  IFP   +  
Sbjct: 81  GAYSGLSTYVMWRHPLGRWGGKIAGLLLITITTGIGWYAVETWLFGIVMSEIFPNNPFFS 140

Query: 126 VIVL----GILVTAWTIVGPERWRWLEKLSVVL-LGVLSVWLLYVIFSKYSFSELWNKPG 180
           V V     GIL+T  T VG     +L   ++   + ++++ +  V+  K  F  +     
Sbjct: 141 VGVAAIWGGILMTIMTYVGYRMLSFLSYFTIPFHIWLIAIGIAIVLALKGGFHTVMAAVP 200

Query: 181 TGGLSLLIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFLGALSN 240
           T  +SLL  +   I +  +      D SRFAKS  DA +  +   +    F    G    
Sbjct: 201 TSHMSLLDGISATIGLYSAGTIISPDISRFAKSAKDAGYAWFAHIIFLYPFLILGGVAIV 260

Query: 241 VAMGKEDPISLIAAYGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVLLV 300
           +A G     + +   G+G+  +LI++         ++YS S++  N+ P    +   ++ 
Sbjct: 261 LATGSYLITNAMLELGMGVGVLLIIVFGQFIINTDNLYSGSLSLVNLIPMRR-EIASVIN 319

Query: 301 GTLGTLLALVF------PVDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADE 354
           G +GT +A          +  +E F+ L+G     +  I++ D+++VK+  +  +     
Sbjct: 320 GVIGTAIAAYVGFSAGSSITPFENFISLLGDFLPAMGGIVLADFYIVKKYVNKIQDPHKR 379

Query: 355 SIRAPGIIAWVIGFILYLSLTMESLIG----ISVPVLSQIGNEIGASIPVFLITMVLYYI 410
               P    + I     L+L + S+IG      +P ++ +       +  FL  +++YYI
Sbjct: 380 YEFVPNNKYYNINIAGILALALGSIIGYFVNAGIPAINSL-------VTGFLSYIIIYYI 432

Query: 411 L 411
           +
Sbjct: 433 I 433


>pir||A83387 probable transporter (membrane subunit) PA2073 [imported] -
           Pseudomonas aeruginosa (strain PAO1)
           >gi|9948083|gb|AAG05461.1|AE004634_4 (AE004634) probable
           transporter (membrane subunit) [Pseudomonas aeruginosa]
           Length = 476
           
 Score =  106 bits (261), Expect = 7e-22
 Identities = 106/440 (24%), Positives = 183/440 (41%), Gaps = 39/440 (8%)

Query: 6   PVKEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKEALAI--IILGHLLGNAVMSL 63
           P  E+    W     WF  +F +  +  G    P L L    +I  I+LG   G   M+ 
Sbjct: 21  PRHERHGKVWHQAPFWFTGNFVLTTMVTG-FTGPALGLGALYSILAIVLGVCFGTFFMAF 79

Query: 64  IAIEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPGTYY 123
            A +G   GLP M+ SR   G +G+++P        IG+    +I+   A++ + PG   
Sbjct: 80  HANQGPRMGLPQMIQSRAQFGLRGAIVPFAAVVFVYIGFNVFNVILATDAINTVLPGHRA 139

Query: 124 AWVIVLGILVTAWTIVGPER----WRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKP 179
            W ++L  +     IVG +      RWL  + + + GVL+V  L    S  + + L   P
Sbjct: 140 PWYVLLIGVAVLLAIVGHDLLHTVQRWLTYVMIAVFGVLTVSALR---SLEADAALGGTP 196

Query: 180 GTGGLSLLIALDLVIAMPLSWAPTIADYSRF----AKSRADAAWGTYLGHLVGSAFCYFL 235
                + L+ L       +S+A  ++DYSR+      +R    W TYLG    + +   L
Sbjct: 197 AFSWSAFLVQLSAAAGYQISYAVYVSDYSRYLPHETPTRKVIFW-TYLGAAGSALWLMSL 255

Query: 236 GALSNVAMGKEDPISLIAAYG-------------LGIPAMLIVLISTLNTTFMDIYSASI 282
           GA    A+   D I  +   G             + +PA++ ++        +   SA  
Sbjct: 256 GAFLASALPAPDAIGSVREVGNRLYPGFGTFTVLIAVPALVGIMAVNCYGAMLTSLSAID 315

Query: 283 TWKNINPKANLK-TQVLLVGTLGTLLALVFP---VDKYEAFLLLIGGAFVPLAAIMITDY 338
            ++ + P  NL+ T + ++  +   +AL  P   +  +  F+LL+    VP  A+ + D+
Sbjct: 316 AFRKVTPTLNLRVTGIGVIALVVFGVALSIPESYLGSFNTFVLLMLYFLVPWTAVNLVDF 375

Query: 339 FLVKR-EYDAEKLLADESIRA----PGIIAWVIGFILYLSLTMESLIGISVPVLSQIGNE 393
           + V+   Y   ++   E I      PG+ A++ G  L   +   SL   S P    +G  
Sbjct: 376 YFVRNGHYAISEIFNPEGIYGHWGRPGLSAYLAG--LLAMVPFMSLSFYSGPFAVALGGA 433

Query: 394 IGASIPVFLITMVLYYILSR 413
             A +   L+   +Y  + R
Sbjct: 434 DVAFVVGLLVAGAVYAFMCR 453


>pir||T35663 probable transmembrane protein - Streptomyces coelicolor
           >gi|4007738|emb|CAA22422.1| (AL034447) putative
           transmembrane protein [Streptomyces coelicolor A3(2)]
           Length = 485
           
 Score =  103 bits (255), Expect = 3e-21
 Identities = 109/435 (25%), Positives = 183/435 (42%), Gaps = 43/435 (9%)

Query: 18  FSIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGH--LLGNAVMSLIAIEGQETGLPT 75
           F  W GA+  + ++  GA L     L    A+++ G   ++   ++ LI I G+  G P 
Sbjct: 32  FPTWVGANISVLLLTMGASLVVAYRLNFWQALVVAGAAPVVSYGLVGLIGIAGKRGGAPG 91

Query: 76  MVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARA----LDVIF---PGTYYAWVIV 128
           M LSR   G +G++LP  L ++   GW  I  + GA A    LD++F     +    V +
Sbjct: 92  MALSRAVFGQRGNLLPGSLIWVARWGWETINAVTGAYALLTVLDIVFGIRANSVLDMVTL 151

Query: 129 LGILVTAWTI--VGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPGTGGLSL 186
           L  +V  + I  +G    +   K +  L G  SV +L  +     +S ++++      ++
Sbjct: 152 LAFVVATFAISGLGINAVQKCNKYAAYLFGAFSVLVLGYLVVDTDWSAVFDRSAGSVAAM 211

Query: 187 LIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFL-----GALSNV 241
           +  + L+ A  +SW P+  D++R+    A +     +G  VG A    L     GA+  V
Sbjct: 212 ITGVGLIAAGGVSWIPSAPDFTRYLPRTASSK--GIVGVTVGGAGIVVLPMVLMGAVMAV 269

Query: 242 A----MGKEDPISL---IAAYGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLK 294
           +        DP+S    I    + +P +LI LI  L    M +YSA  T + +  K    
Sbjct: 270 STPDLASAADPVSFLGEILPTWIAVPYLLIALIGMLLINSMSMYSAGFTAQTLGFKVPRH 329

Query: 295 TQV-------LLVGTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDA 347
             V       L+ G +  L+A  F +  + AFL L+  AF     +   D  L  REYD 
Sbjct: 330 WAVSVNAVISLVFGGVLMLVATSF-MGSFIAFLSLLAVAFSAWVGVFGAD-MLRGREYDG 387

Query: 348 EKLLADESIRA---------PGIIAWVIGFILYLSLTMESLIGISVPVLSQIGNEIGASI 398
           E L       A           ++AW +G    L  T        +   + +G      +
Sbjct: 388 EALADTGRTSAYWYRGGFSPAAVVAWAVGLAAGLMFTTSDWFTGPLATDNFVGEYGLGWV 447

Query: 399 PVFLITMVLYYILSR 413
              +I+ +LY +L +
Sbjct: 448 ATVVISALLYAVLPK 462


>gb|AAG02128.1|AF146701_4 (AF146701) permease homolog HyuP [Arthrobacter aurescens]
           Length = 478
           
 Score = 98.7 bits (242), Expect = 1e-19
 Identities = 93/378 (24%), Positives = 167/378 (43%), Gaps = 32/378 (8%)

Query: 19  SIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTMVL 78
           +IWF     +A+  A   LT    + + +  I  G  +   V+          G+   V 
Sbjct: 34  AIWFAMAIQVAIFIAAGQLTASFQVWQVIVAIAAGCTIAVVVVFFTQSAAIRWGINFTVA 93

Query: 79  SRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFP-----GTYYAWVIVLGILV 133
           +R P G +GS++P  +  L  + W      +GA ALD I            WV++ G + 
Sbjct: 94  ARMPFGIRGSLIPIVVKALLSLFWFGFQTWLGALALDEITRILTGFSNLTLWVLIFGAVQ 153

Query: 134 TAWTIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSK--YSFSELWNKPG-TGGLSLLIAL 190
              T  G    RW+   +  +L  + V+++Y++ +    +  E+ +  G T G+    A+
Sbjct: 154 VVTTFYGISFIRWMNIFAAPVLLAMGVFMVYLMLNGAGVTLGEVMSMGGETPGMPFSTAV 213

Query: 191 DLVIAMPLSWAPTIADY----------SRFAKSRADAAWGT--YLGHLVGSAFCYFLGAL 238
            + +   ++   +I D           SR  + ++DA +    + G +  S    F+GA 
Sbjct: 214 MIFVGGWIAVVVSIHDIVKECKVSPSESREGRVKSDAKYAAAQWWGMVPASVIFGFIGAA 273

Query: 239 SNVAMGKEDPISLIA------AYGLGIPAMLIVLISTLNTT-FMDIYSASITWKNINPKA 291
           S V +G+ +P+  I       +  + I   + VL++T +T    ++ S + T  +  P+ 
Sbjct: 274 SMVLVGEWNPVFAITKVVGEVSVPMAILFQVFVLLATWSTNPAANLLSPAYTLCSTFPRV 333

Query: 292 -NLKTQVLLVGTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKL 350
            + KT V++ G +G L+      D   +FL ++  A  PLA IMITDYFLV+R     ++
Sbjct: 334 FSFKTGVIVSGAIGLLMMPWQFADTLNSFLNILASALGPLAGIMITDYFLVRR----GRV 389

Query: 351 LADESIRAPGIIAWVIGF 368
              +  R  GI  +  GF
Sbjct: 390 SLQDLYRTKGIYTYWHGF 407


>sp|P94575|YWOE_BACSU HYPOTHETICAL 54.0 KD PROTEIN IN NRGA-USD INTERGENIC REGION
           >gi|7430010|pir||H70064 permease homolog ywoE - Bacillus
           subtilis >gi|1684649|emb|CAB05378.1| (Z82987) unknown,
           similar to uracil permease from Schizosaccharomyces
           pombe [Bacillus subtilis] >gi|2636172|emb|CAB15664.1|
           (Z99122) similar to permease [Bacillus subtilis]
           Length = 490
           
 Score = 82.7 bits (201), Expect = 7e-15
 Identities = 113/458 (24%), Positives = 190/458 (40%), Gaps = 86/458 (18%)

Query: 19  SIWFGADFGIAVI-WAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTMV 77
           SIW G    I      G L+   LS  + LAIII   L+    ++L    G + GLP  V
Sbjct: 35  SIWMGCIHNIPTYATVGGLIAIGLSPWQVLAIIITASLILFGALALNGHAGTKYGLPFPV 94

Query: 78  LSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPGTYYAWVIVLGILVTAWT 137
           + R   G  G+ +P+ L     I W  I    G+ AL+++    +  W    G +   W 
Sbjct: 95  IIRASYGIYGANIPALLRAFTAIMWLGIQTFAGSTALNILLLNMWPGW----GEIGGEWN 150

Query: 138 IVGPER-------WRWLEKLSVVLLGVLS-----VW---LLYVIFSK------------- 169
           I+G          + W   L V+  G+ S     VW   L+Y++F               
Sbjct: 151 ILGIHLSGLLSFVFFWAIHLLVLHHGMESIKRFEVWAGPLVYLVFGGMVWWAVDIAGGLG 210

Query: 170 ---------YSFSE-LWNKPGTGGLSLLIALDLVIAMPLSWAPTIADYSRFAKSRADAAW 219
                    ++FSE  W  P   G++ +I +   + +       I D++RFA+++ +   
Sbjct: 211 PIYSQPGKFHTFSETFW--PFAAGVTGIIGIWATLIL------NIPDFTRFAETQKEQIK 262

Query: 220 GTYLGHLVGSAFCYFLGALSNVAMGKE--------DPISLIAAYG---LGIPAMLIVLIS 268
           G + G  +   F  F  A   V  G +        D + ++A +    + + +++ + I+
Sbjct: 263 GQFYG--LPGTFALFAFASITVTSGSQVAFGEPIWDVVDILARFDNPYVIVLSVITLCIA 320

Query: 269 TLNTTF-MDIYSASITWKNINPK-ANLKTQVLLVGTLGTLLA---LVFPVDKYEAFLLLI 323
           T++     +I S +    N  PK  N K    +   L        L+       AFL LI
Sbjct: 321 TISVNVAANIVSPAYDIANALPKYINFKRGSFITALLALFTVPWKLMESATSVYAFLGLI 380

Query: 324 GGAFVPLAAIMITDYFLV-KREYDAEKLLAD-------ESIRAPGIIAWVIGFILYLSLT 375
           GG   P+A +M+ DYF++ KRE   + L ++       +        A ++G ++     
Sbjct: 381 GGMLGPVAGVMMADYFIIRKRELSVDDLYSETGRYVYWKGYNYRAFAATMLGALI----- 435

Query: 376 MESLIGISVPVLSQIGNEIGASIPVFLITMVLYYILSR 413
             SLIG+ VPVL  +  +I   + V LI+ + Y +L R
Sbjct: 436 --SLIGMYVPVLKSL-YDISWFVGV-LISFLFYIVLMR 469


>gi|6320902 purine-cytosine permease; Fcy21p [Saccharomyces cerevisiae]
           >gi|1723597|sp|P40039|YEP0_YEAST HYPOTHETICAL 58.1 KD
           PROTEIN IN PET117-CEM1 INTERGENIC REGION
           >gi|1321943|emb|CAA66032.1| (X97346) FCYY [Saccharomyces
           cerevisiae] >gi|1381128|gb|AAB64596.1| (U18813) Fcy21p:
           Purine-cytosine permease [Saccharomyces cerevisiae]
           Length = 528
           
 Score = 77.3 bits (187), Expect = 3e-13
 Identities = 94/424 (22%), Positives = 183/424 (42%), Gaps = 56/424 (13%)

Query: 19  SIWFGADFGIAVIWAGAL--LTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTM 76
           S+WF A+  +     GAL  +   L+  +++ +II  +LLG   ++  ++ G E GL  M
Sbjct: 89  SMWFSANMVLPAYAIGALGPMVFDLNFGQSVFVIIFFNLLGLVSVAFFSVFGAELGLRQM 148

Query: 77  VLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPG----TYYAWVIVLG-- 130
           +LSR  +G   + + SF+N++  IGW  +  +  ++ L+++ PG     +   ++++G  
Sbjct: 149 ILSRYLVGNIAARIFSFINFIACIGWGIVNTVASSQVLNMVNPGHQCPLWAGCIVIIGAT 208

Query: 131 ILVTAW---TIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPGTGGLSLL 187
           ++VT +    I   E+W W+   +V L+ +  +        K+   E  + P T G ++L
Sbjct: 209 VIVTFFGYGVIHAYEKWAWVPNFAVFLVIIARL----ARSKKFVLGEWTSGPTTAG-NVL 263

Query: 188 IALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSA----FCYFLG-ALSNVA 242
                V      W    ADY+ +   + +  +  +   +VG A    F   LG A++  A
Sbjct: 264 SFGSTVYGFAAGWTTYAADYTVYMPRKTN-KYKIFFSLVVGLATPLYFTMILGAAVAMAA 322

Query: 243 MG--------KEDPISLI--------AAYGLGIPAMLIVLISTLNTTFMDIY----SASI 282
           +G         E+ I  +        + +G G    +++ +ST+     ++Y    S   
Sbjct: 323 IGDPAWKTYYDENSIGGLTFAVLVPNSVHGFGQFCCVLLSLSTIANNVPNMYTIALSVQA 382

Query: 283 TWKNINPKANLKTQVLLVGTLGTLLALVFPVDKY-----EAFLLLIGGAFVPLAAIMITD 337
           TW+   P A +   +  +      L +  P   Y       F+  IG       AI  ++
Sbjct: 383 TWE---PLAKVPRVIWTLLGNAAALGIAIPACYYFSTFMNYFMDSIGYYLAIYIAIACSE 439

Query: 338 YFLVKREYDAEKLLADES-----IRAPGIIAWVIG-FILYLSLTMESLIGISVPVLSQIG 391
           +F+ +R + A  +   +S     I   G  A ++G F + L +     +G    ++   G
Sbjct: 440 HFIYRRSFSAYNVDDWDSWERLPIGIAGTAALIVGAFGVALGMCQTYWVGEISRLIGDYG 499

Query: 392 NEIG 395
            +IG
Sbjct: 500 GDIG 503


>pir||T28687 hypothetical protein - Streptomyces coelicolor
           >gi|3127838|emb|CAA18904.1| (AL023496) hypothetical
           protein [Streptomyces coelicolor A3(2)]
           Length = 522
           
 Score = 76.9 bits (186), Expect = 4e-13
 Identities = 112/467 (23%), Positives = 198/467 (41%), Gaps = 75/467 (16%)

Query: 6   PVKEKIFDFWSNFSIWFGADFGIAVIW--AGALLTPYLSLKEALAIIILGHLLGNAVMSL 63
           PV+ + +  ++  ++W G     A  W  A  L+   +  K+A+  I L +L+  A M L
Sbjct: 49  PVEGRTWTTYNFSALWVGMAHNTAS-WTLASGLIAVGMDWKQAVFTIALANLIVLAPMLL 107

Query: 64  IAIEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIF----- 118
               G + G+P  V +R   G +G+ LP+ +  L   GW  I   +G  A+  +      
Sbjct: 108 TGHAGPKYGIPFPVFARASFGIRGANLPAVVRALVACGWFGIQTWIGGEAIYFLAGKLIG 167

Query: 119 -----PGTY--YAWVIVLGILVTAWTIVGPERWRWLEKL--------SVVLLGVLSVWLL 163
                 GT+  +AW + L   +  W +     +R +E +          VL+G   V L 
Sbjct: 168 DGWTNAGTFGGHAWTMWLSFAI-FWALQVAIIYRGMETIRRFENWAAPFVLVGAF-VMLW 225

Query: 164 YVIFSKYSFSELWNKP---GTGGLSLLIALDLVIAMPLSWAP---TIADYSRFAKSRADA 217
           ++      F  L+++P   G GG    +    ++ M   W+     I D++R+ KS+   
Sbjct: 226 WMADKAGGFGPLFDQPSRLGWGGDFWKLFWPSLMGMIGFWSTLSLNIPDFTRYGKSQRAQ 285

Query: 218 AWGTYLGHLVGSAFCYFLGAL----SNVAMGKE--DPISLIA----AYGLGIPAMLIVLI 267
             G  LG         FL  +    S    G+   DP+ L A      GL + A++ VL+
Sbjct: 286 TRGQALGLPTTMTLFAFLSVMVTSGSQAVYGEPIWDPVQLAAKTDNVVGL-LFALVTVLV 344

Query: 268 STLNTTF-MDIYSASITWKNINP-KANLKTQVLLVGTLGTLLALVFPVDKYE-------A 318
           +TL+     ++ S +  + N+ P + + +   L+   L     L+FP   Y         
Sbjct: 345 ATLSVNIAANLVSPAFDFSNVAPRRVSFRAGALITSVLA---VLIFPWKLYSDPQGYIFT 401

Query: 319 FLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADESIRA-----------PGIIAWVIG 367
           +L L+GG    +A I+I DY++++R   A   L D   R              ++A+V+G
Sbjct: 402 WLGLVGGLLGTVAGILIADYWILRR---ARLHLVDLYRRGGRYWYEGGWNWRAVLAFVVG 458

Query: 368 FILYL-SLTMESLI-GISVPVLSQIGN-----EIGASIPVFLITMVL 407
            +L +       L+ G  VP L  + +      +  S+ ++LI M+L
Sbjct: 459 GVLAVGGADFHPLVDGRPVPFLEPLADYGWAVGLATSLVLYLILMLL 505


>gb|AAG02126.1|AF146701_2 (AF146701) transport protein homolog [Arthrobacter aurescens]
           Length = 468
           
 Score = 76.9 bits (186), Expect = 4e-13
 Identities = 105/424 (24%), Positives = 181/424 (41%), Gaps = 51/424 (12%)

Query: 30  VIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTMVLSRGPLGGKGS- 88
           V+    ++   LS+ +A+ +I++ + L   +M   A  G  +G+PT +++R   G +G+ 
Sbjct: 42  VVIGATIMVFGLSMWQAVVVILVANSL-MFLMGWFASIGAASGVPTSIITRALFGMRGNK 100

Query: 89  --------VLPSFLNYLQLIGWTAIMLIVGAR---ALDVIFPGTYYAWVIVLGILVTAWT 137
                   VL + +  + L+  T   L+V  R   A DV          IV GI+V A T
Sbjct: 101 VFGAGVVVVLSTLVTIVNLVIGTQGGLVVAERLGMAPDVA------TTAIVCGIIVLAST 154

Query: 138 IVGPERWRWLEKLSVVLLGVLS---VWLLYVIFSKYSFSELWNKPGTGG-LSLLIALDLV 193
            +    +  + K S VL  +++   V L + +F K   +     P     +  ++AL L 
Sbjct: 155 GLAIYGYNMMVKTSGVLTVIIAAAFVLLGFFVFQKVDLASFQPVPTENPVIGFIVALTLC 214

Query: 194 IAMPLSWAPTIADYSRFAKS---RADAAWGTYLGHLVGSAFCYFLGALSNVAMGKEDPIS 250
           IAMPLSW  + AD++R   S   R        LG ++       +G L+  A    +P++
Sbjct: 215 IAMPLSWG-SAADFARHIPSTTRRKPIVLAVGLGGMIPLVGLELVGVLAATATDMSEPVT 273

Query: 251 ---LIAAYGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVL---LVGTLG 304
               +     G   +++++I ++  T M IY  S+  +      +    V    L   +G
Sbjct: 274 GLMNLVPDWFGTVLVVVIVIGSIMNTVMTIYGGSLAVQAAGVPVSRVVAVTGLGLTAAIG 333

Query: 305 TLLALVFP---VDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADES------ 355
           T   L F    ++  +  L  +G   +PL AI + D    K  YD    L+D S      
Sbjct: 334 TAYVLFFADSFLNILQLGLTCLGSVAMPLTAIYLVDSVRRKGRYDG-VALSDPSQGGPYW 392

Query: 356 ----IRAPGIIAWVIGFIL-YLSLTMESLIGISVPVLSQIGNEIGASIPVFLITMVLYYI 410
                R  GI A + G ++  LSL   S  G   P+ + +G    + +    +  VL+  
Sbjct: 393 HRGGFRLSGICALLGGSVVALLSLNGASYQG---PIAALLGGIDMSIVLGGTVAAVLFVA 449

Query: 411 LSRR 414
           LSR+
Sbjct: 450 LSRQ 453


>pir||S50563 hypothetical protein YER060w - yeast (Saccharomyces cerevisiae)
           Length = 528
           
 Score = 76.5 bits (185), Expect = 5e-13
 Identities = 94/424 (22%), Positives = 183/424 (42%), Gaps = 56/424 (13%)

Query: 19  SIWFGADFGIAVIWAGAL--LTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTM 76
           S+WF A+  +     GAL  +   L+  +++ +II  +LLG   ++  ++ G E GL  M
Sbjct: 89  SMWFSANMVLPAYAIGALGPMVFDLNFGQSVFVIIFFNLLGLVSVAFFSVFGAELGLRQM 148

Query: 77  VLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPG----TYYAWVIVLG-- 130
           +LSR  +G   + + SF+N++  IGW  +  +  ++ L+++ PG     +   ++++G  
Sbjct: 149 ILSRYLVGNIAARIFSFINFIACIGWGIVNTVASSQVLNMVNPGHQCPLWAGCIVIIGAT 208

Query: 131 ILVTAW---TIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPGTGGLSLL 187
           ++VT +    I   E+W W+   +V L+ +  +        K+   E  + P T G ++L
Sbjct: 209 VIVTFFGYGVIHAYEKWAWVPNFAVFLVIIARL----ARSKKFVLGEWTSGPTTAG-NVL 263

Query: 188 IALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSA----FCYFLG-ALSNVA 242
                V      W    ADY+ +   + +  +  +   +VG A    F   LG A++  A
Sbjct: 264 SFGSTVYGFAAGWTTYAADYTVYMPRKTN-KYKIFFSLVVGLATPLYFTMILGAAVAMAA 322

Query: 243 MG--------KEDPISLI--------AAYGLGIPAMLIVLISTLNTTFMDIY----SASI 282
           +G         E+ I  +        + +G G    +++ +ST+     ++Y    S   
Sbjct: 323 IGDPAWKTYYDENSIGGLTFAVLVPNSVHGFGQFCCVLLSLSTIANNVPNMYTIALSVQA 382

Query: 283 TWKNINPKANLKTQVLLVGTLGTLLALVFPVDKY-----EAFLLLIGGAFVPLAAIMITD 337
           TW+   P A +   +  +      L +  P   Y       F+  IG       AI  ++
Sbjct: 383 TWE---PLAKVPRVIWTLLGNAAALGIAIPACYYFSTFMNYFMDSIGYYLAIYIAIACSE 439

Query: 338 YFLVKREYDAEKLLADES-----IRAPGIIAWVIG-FILYLSLTMESLIGISVPVLSQIG 391
           +F+ +R + A  +   +S     I   G  A + G F + L +     +G    ++ + G
Sbjct: 440 HFIYRRSFSAYNVDDWDSWERLPIGIAGTAALIAGAFGVALGMCQTYWVGEISRLIGEYG 499

Query: 392 NEIG 395
            +IG
Sbjct: 500 GDIG 503


>sp|Q01266|YHYC_PSESN HYPOTHETICAL PROTEIN IN HYUC 3'REGION (ORF 5)
           >gi|216834|dbj|BAA01380.1| (D10494) ORF5 unidentified
           protein [Pseudomonas sp.]
           Length = 245
           
 Score = 76.1 bits (184), Expect = 7e-13
 Identities = 56/242 (23%), Positives = 115/242 (47%), Gaps = 11/242 (4%)

Query: 8   KEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIE 67
           KE+     + F +W G    +      A L P LS  + +   ILG+L+   +++L+   
Sbjct: 6   KERNMSSIAYFILWVGIAVQLVTPITAAQLYPALSPLQIIIACILGNLIVAILLTLLGDI 65

Query: 68  GQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFP-----GTY 122
           G   G+P  V  R   G  G+ +P  +  +  + W      +GA ALD I          
Sbjct: 66  GVRYGIPYAVYIRASFGYLGAHIPGIVRAVPAVFWFGFQTWMGAYALDAIMEMLTGYSNL 125

Query: 123 YAWVIVLGILVTAWTIVGPE---RWRWLEKLSVVLLGVLSVWLLYVIFSKY-SFSELWNK 178
              +I+ G++    T +G E   ++ WL   S++++G+  +  +Y++   + +FSE+++ 
Sbjct: 126 TLLIILFGVVQIINTAMGMEAITKFEWLASPSILIIGI--ILQVYIMKQHHLTFSEIFSH 183

Query: 179 PGTGGLSLLIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFLGAL 238
            G GG+S+  A+ +++   ++ A    D++RF K++  ++   +     GS + +  G +
Sbjct: 184 GGDGGVSMGYAVVVMMGTYITMALNAPDFTRFLKTKTGSSEPNWWKVNKGSFWAHTFGLI 243

Query: 239 SN 240
            +
Sbjct: 244 GS 245


>emb|CAC12338.1| (AL445066) purine-cytosine permease related protein [Thermoplasma
           acidophilum]
           Length = 480
           
 Score = 76.1 bits (184), Expect = 7e-13
 Identities = 88/366 (24%), Positives = 158/366 (43%), Gaps = 33/366 (9%)

Query: 6   PVKEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIA 65
           P   +I   W     W  A         G LL P L L + L  I +  L+G   + + +
Sbjct: 34  PGTSRIMGPWKMTVFWSMASASALTPLIGYLLYP-LGLIDMLIAISIAFLIGFVPVGIFS 92

Query: 66  IEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPGTYYAW 125
             G+   +P M++SR  LG   S + S +     +GW  +  I G   L  +   +   W
Sbjct: 93  EMGRTIPVPAMIISRKTLGYASSSVMSLIFTFVNLGWFGLNDITGGLILASVTSSSPIIW 152

Query: 126 VIVLGILVTAWTIVGPER----WRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPGT 181
           +  + I+     + G +     +R+   L V   G+L+ +LL+ ++    ++ L   P T
Sbjct: 153 ISFMAIVQIMLVLFGAKYLEKFYRYTAILLVFSYGILT-YLLFRVYRPDMYAVL--HPST 209

Query: 182 GGLSLLIALDLVIAMP-LSWAPTIADYSRFAKSR-----ADAAWGTYLGHLVGSAF-CYF 234
             ++   A+ LV+A   L+WA  ++  SRFA+ R     A    G ++   +G     Y 
Sbjct: 210 -AVNWGSAIGLVLAFSILAWAYKVSTISRFARKREAGEPALERSGFFMAPSIGIIVPVYV 268

Query: 235 LGALSNVAMGKEDPISLIAA--YGLG-------IPAMLIVLISTLNTTFMDIYSASITWK 285
           +G+L  ++    +  +L A    GLG       I A +   ++ ++T  M++Y A+    
Sbjct: 269 MGSLGLISEAAAENWNLAAVRFSGLGSIGGAVAIIASIGASLAIIHTNSMNLYPATADLL 328

Query: 286 N-----INPKANLKTQVL---LVGTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMITD 337
           +      N +     Q +   ++GTLG +LA    ++    FL L G    P   ++I D
Sbjct: 329 SAIEGLFNKRLRKFAQPISTAILGTLGAVLAYAGILNYASGFLNLSGSIIFPFTFVLIAD 388

Query: 338 YFLVKR 343
           +F++ R
Sbjct: 389 WFMMNR 394


>pir||T48383 uracil transporter-like protein - Arabidopsis thaliana
           >gi|7378642|emb|CAB83318.1| (AL162751) uracil
           transporter-like protein [Arabidopsis thaliana]
           Length = 599
           
 Score = 75.7 bits (183), Expect = 9e-13
 Identities = 89/388 (22%), Positives = 166/388 (41%), Gaps = 51/388 (13%)

Query: 2   EEIKPV--KEKIFDFWSNFSIWFGADFGIAVIW-AGALLTPYLSLKEALAIIILGHLLGN 58
           +++KP    ++ F +    S+W G   G+   + AG+L+   ++  + +A ++  +L+  
Sbjct: 120 DDLKPTTPSQRTFSWLDMSSLWIGLVVGVPTYYLAGSLVDLGMAWWQGIATVVTANLILL 179

Query: 59  AVMSLIAIEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIF 118
             + L A  G   G+   VL+R   G +G+ +P+ L  L   GW  I   +G  A+ ++ 
Sbjct: 180 VPLVLTAQPGTLYGISFPVLARSSFGIRGAHIPTLLRALVGCGWYGIETWIGGEAIFLLL 239

Query: 119 PGTYYAWVIVLGILVTAWTIVGPERWR-----WLEKLSVVLLGV-----LSVWLLYVIFS 168
           PG      +   +    W    P  +      WL +L +V  G+     L  +   ++ S
Sbjct: 240 PGHIKKSALSHTL---PWLGTSPLEFSCFIVFWLAQLCIVWRGMDGIRKLEKYSAPILIS 296

Query: 169 KYSFSELWNKPGTGGLSLLIALDLVIAMPLSW-----------------APTIADYSRFA 211
             S    W+    GG   +++L   +     W                 A  I D+SRFA
Sbjct: 297 LTSCLLAWSYLKAGGFGHMLSLSSKLTSAQFWTLFFPSLTANISFWATLALNIPDFSRFA 356

Query: 212 KSRADAAWGTYLGHLVGSAFCYFLG----ALSNVAMGK--EDPISLIAAYGLGIPAMLIV 265
           KS+ D   G  +G  V      F+G    + +++  G+   +PI L+   G G+   L+ 
Sbjct: 357 KSQTDQIIG-QVGLPVFMGLFTFVGVAVTSSTSIIFGRVISNPIELLGQIG-GLATTLLA 414

Query: 266 LI----STLNTTF-MDIYSASITWKNINPK-ANLKTQVLLVGTLGTLLALVFPVDKYEAF 319
           ++    +TL T    ++ + +    N+NPK         L   LG +      +   E+F
Sbjct: 415 IVGISLATLTTNIAANVVAPANALVNLNPKFFTFGRGAFLTAVLGIVFQPWRLLKSSESF 474

Query: 320 LL--LIGGAFV--PLAAIMITDYFLVKR 343
           +   LIG + +  P+  I++ DY+L+K+
Sbjct: 475 VYTWLIGYSALLGPIGGIILVDYYLIKK 502


>gb|AAA25848.1| (M72717) ORF 5 [Pseudomonas sp.]
           Length = 233
           
 Score = 75.3 bits (182), Expect = 1e-12
 Identities = 53/220 (24%), Positives = 107/220 (48%), Gaps = 11/220 (5%)

Query: 8   KEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIE 67
           KE+     + F +W G    +      A L P LS  + +   ILG+L+   +++L+   
Sbjct: 6   KERNMSSIAYFILWVGIAVQLVTPITAAQLYPALSPLQIIIACILGNLIVAILLTLLGDI 65

Query: 68  GQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFP-----GTY 122
           G   G+P  V  R   G  G+ +P  +  +  + W      +GA ALD I          
Sbjct: 66  GVRYGIPYAVYIRASFGYLGAHIPGIVRAVPAVFWFGFQTWMGAYALDAIMEMLTGYSNL 125

Query: 123 YAWVIVLGILVTAWTIVGPE---RWRWLEKLSVVLLGVLSVWLLYVIFSKY-SFSELWNK 178
              +I+ G++    T +G E   ++ WL   S++++G+  +  +Y++   + +FSE+++ 
Sbjct: 126 TLLIILFGVVQIINTAMGMEAITKFEWLASPSILIIGI--ILQVYIMKQHHLTFSEIFSH 183

Query: 179 PGTGGLSLLIALDLVIAMPLSWAPTIADYSRFAKSRADAA 218
            G GG+S+  A+ +++   ++ A    D++RF K++  ++
Sbjct: 184 GGDGGVSMGYAVVVMMGTYITMALNAPDFTRFLKTKTGSS 223


>sp|P75712|ALLP_ECOLI PUTATIVE ALLANTOIN PERMEASE (ALLANTOIN TRANSPORT PROTEIN)
           >gi|1773191|gb|AAB40263.1| (U82664) similar to
           Pseudomonas sp. ORF5 [Escherichia coli]
           >gi|2735237|gb|AAB93852.1| (U89279) GlxB2 [Escherichia
           coli]
           Length = 484
           
 Score = 72.2 bits (174), Expect = 1e-11
 Identities = 92/398 (23%), Positives = 169/398 (42%), Gaps = 46/398 (11%)

Query: 5   KPVKEKIFDFWSNFSIWFGADFGIA-VIWAGALLTPYLSLKEALAIIILGHLLGNAVMSL 63
           K   ++ +  ++ F++W G+   +   +  G      LS    +  IIL      AVM L
Sbjct: 20  KTQSQRTWKTFNYFTLWMGSVHNVPNYVMVGGFFILGLSTFSIMLAIILSAFFIAAVMVL 79

Query: 64  IAIEGQETGLPTMVLSRGPLGGKGSVLPSFL-NYLQLIGWTAIMLIVGARA----LDVIF 118
               G + G+P  ++ R   G +G++ P  L   +  I W  +    G+ A    +  I+
Sbjct: 80  NGAAGSKYGVPFAMILRASYGVRGALFPGLLRGGIAAIMWFGLQCYAGSLACLILIGKIW 139

Query: 119 PG--TYYAWVIVLGI----LVT---AWTI---VGPERWRWLEKLSVVL-------LGVLS 159
           PG  T      +LG+    L+T    W +   +G    + L K + +L        G ++
Sbjct: 140 PGFLTLGGDFTLLGLSLPGLITFLIFWLVNVGIGFGGGKVLNKFTAILNPCIYIVFGGMA 199

Query: 160 VWLLYVIFSKYSFSEL---WNKPGTGGLSLLIALDLVIAMPLSWAPTIADYSRFAKSRAD 216
           +W + ++     F  +     K   GG   L+ ++ V+A+  + A + +D+++ A S  +
Sbjct: 200 IWAISLVGIGPIFDYIPSGIQKAENGGFLFLVVINAVVAVWAAPAVSASDFTQNAHSFRE 259

Query: 217 AAWGTYLGHLVG------SAFCYFLGALSNVAMGKEDPISLIAAYG---LGIPAMLIVLI 267
            A G  LG +V       +  C   GA  +      + + ++  +        A+L++L+
Sbjct: 260 QALGQTLGLVVAYILFAVAGVCIIAGASIHYGADTWNVLDIVQRWDSLFASFFAVLVILM 319

Query: 268 STLNTTFM-DIYSASITWKNINP-KANLKTQVLLVGTLGTLLA---LVFPVDKYEAFLLL 322
           +T++T    +I  A      I P K   K  VL+   +  L+    L+   D    FL +
Sbjct: 320 TTISTNATGNIIPAGYQIAAIAPTKLTYKNGVLIASIISLLICPWKLMENQDSIYLFLDI 379

Query: 323 IGGAFVPLAAIMITDYFLVKREYDAEKLLADESIRAPG 360
           IGG   P+  +M+  YF+V R     ++  DE   APG
Sbjct: 380 IGGMLGPVIGVMMAHYFVVMR----GQINLDELYTAPG 413


>emb|CAA36040.1| (X51751) cytosine-purine permease (AA 1-533) [Saccharomyces
           cerevisiae]
           Length = 533
           
 Score = 71.8 bits (173), Expect = 1e-11
 Identities = 95/423 (22%), Positives = 182/423 (42%), Gaps = 52/423 (12%)

Query: 19  SIWFGADFGIAVIWAGAL--LTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTM 76
           S+WF A+  IA    GAL  +   L+  +++ +II  +++G   ++  ++ G E GL  M
Sbjct: 92  SMWFSANMVIASYALGALGPMVFGLNFGQSVLVIIFFNIMGLIFVAFFSVFGAELGLRQM 151

Query: 77  VLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPGTYYA---W---VIVLG 130
           +LSR  +G   + + S +N +  +GW  +   V A+ L+++  G+ +    W   +I++G
Sbjct: 152 ILSRYLVGNVTARIFSLINVIACVGWGIVNTSVSAQLLNMMNEGSGHVCPIWAGCLIIIG 211

Query: 131 --ILVTAW---TIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPGTGGLS 185
             +LVT +    I   E+W W+   +V L+ +  +        K+   E W   GT   S
Sbjct: 212 GTVLVTFFGYSVIHAYEKWSWVPNFAVFLVIIAQL----SRSGKFKGGE-WVGGGTTAGS 266

Query: 186 LLIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYF----LGALSNV 241
           +L     +      W    ADY+ +   ++   +  +   + G AF  F    LGA S +
Sbjct: 267 VLSFGSSIFGFAAGWTTYAADYTVY-MPKSTNKYKIFFSLVAGLAFPLFFTMILGAASAM 325

Query: 242 ---------------AMGKEDPISLI--AAYGLGIPAMLIVLISTLNTTFMDIYSASITW 284
                          AMG      L+  +  G G    +++ +ST+     ++Y+ +++ 
Sbjct: 326 AALNDPTWKAYYDKNAMGGVIYAILVPNSLNGFGQFCCVLLALSTIANNIPNMYTVALSA 385

Query: 285 KNI-NPKANLKTQVLLVGTLGTLLALVFPVDKY-----EAFLLLIGGAFVPLAAIMITDY 338
           + +  P A +   V  +      L +  P   Y     E F+  IG       AI  +++
Sbjct: 386 QALWAPLAKIPRVVWTMAGNAATLGISIPATYYFDGFMENFMDSIGYYLAIYIAISCSEH 445

Query: 339 FLVKREYDAEKLLADES-----IRAPGIIAWVIG-FILYLSLTMESLIGISVPVLSQIGN 392
           F  +R + A  +   ++     I   G  A ++G F + L +     +G    ++ + G 
Sbjct: 446 FFYRRSFSAYNIDDWDNWEHLPIGIAGTAALIVGAFGVALGMCQTYWVGEIGRLIGKYGG 505

Query: 393 EIG 395
           +IG
Sbjct: 506 DIG 508


>gi|6320897 purine-cytosine permease; Fcy2p [Saccharomyces cerevisiae]
           >gi|729467|sp|P17064|FCY2_YEAST PURINE-CYTOSINE PERMEASE
           (PCP) (CYTOSINE/PURINE TRANSPORT PROTEIN)
           >gi|1070658|pir||GRBYCP cytosine/purine transport
           protein - yeast (Saccharomyces cerevisiae)
           >gi|603292|gb|AAB64592.1| (U18813) Fcy2p:
           purine-cytosine permease [Saccharomyces cerevisiae]
           Length = 533
           
 Score = 70.2 bits (169), Expect = 4e-11
 Identities = 94/423 (22%), Positives = 181/423 (42%), Gaps = 52/423 (12%)

Query: 19  SIWFGADFGIAVIWAGAL--LTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTM 76
           S+WF A+  IA    GAL  +   L+  +++ +II  +++G   ++  ++ G E GL  M
Sbjct: 92  SMWFSANMVIASYALGALGPMVFGLNFGQSVLVIIFFNIMGLIFVAFFSVFGAELGLRQM 151

Query: 77  VLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPGTYYA---W---VIVLG 130
           +LSR  +G   + + S +N +  +GW  +   V A+ L+++  G+ +    W   +I++G
Sbjct: 152 ILSRYLVGNVTARIFSLINVIACVGWGIVNTSVSAQLLNMVNEGSGHVCPIWAGCLIIIG 211

Query: 131 --ILVTAW---TIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPGTGGLS 185
             +LVT +    I   E+W W+   +V L+ +  +        K+   E W    T   S
Sbjct: 212 GTVLVTFFGYSVIHAYEKWSWVPNFAVFLVIIAQL----SRSGKFKGGE-WVGGATTAGS 266

Query: 186 LLIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYF----LGALSNV 241
           +L     +      W    ADY+ +   ++   +  +   + G AF  F    LGA S +
Sbjct: 267 VLSFGSSIFGFAAGWTTYAADYTVY-MPKSTNKYKIFFSLVAGLAFPLFFTMILGAASAM 325

Query: 242 ---------------AMGKEDPISLI--AAYGLGIPAMLIVLISTLNTTFMDIYSASITW 284
                          AMG      L+  +  G G    +++ +ST+     ++Y+ +++ 
Sbjct: 326 AALNDPTWKAYYDKNAMGGVIYAILVPNSLNGFGQFCCVLLALSTIANNIPNMYTVALSA 385

Query: 285 KNI-NPKANLKTQVLLVGTLGTLLALVFPVDKY-----EAFLLLIGGAFVPLAAIMITDY 338
           + +  P A +   V  +      L +  P   Y     E F+  IG       AI  +++
Sbjct: 386 QALWAPLAKIPRVVWTMAGNAATLGISIPATYYFDGFMENFMDSIGYYLAIYIAISCSEH 445

Query: 339 FLVKREYDAEKLLADES-----IRAPGIIAWVIG-FILYLSLTMESLIGISVPVLSQIGN 392
           F  +R + A  +   ++     I   G  A ++G F + L +     +G    ++ + G 
Sbjct: 446 FFYRRSFSAYNIDDWDNWEHLPIGIAGTAALIVGAFGVALGMCQTYWVGEIGRLIGKYGG 505

Query: 393 EIG 395
           +IG
Sbjct: 506 DIG 508


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.326    0.143    0.438 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 155241751
Number of Sequences: 2977
Number of extensions: 6467489
Number of successful extensions: 22072
Number of sequences better than 1.0e-10: 28
Number of HSP's better than  0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 21994
Number of HSP's gapped (non-prelim): 31
length of query: 414
length of database: 189,106,746
effective HSP length: 52
effective length of query: 362
effective length of database: 157,985,422
effective search space: 57190722764
effective search space used: 57190722764
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.6 bits)
S2: 166 (69.1 bits)