BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1643 (codB-like) DE:PURINE-CYTOSINE PERMEASE related (414 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||F75087 purine-cytosine permease related PAB1643 - Pyrococcu... 823 0.0 pir||A71058 probable cytosine permease - Pyrococcus horikoshii >... 757 0.0 pir||G82032 probable permease NMA0365 [imported] - Neisseria men... 226 3e-58 pir||G81010 conserved hypothetical protein NMB2067 [imported] - ... 220 2e-56 dbj|BAB05601.1| (AP001513) cytosine permease [Bacillus halodurans] 150 4e-35 pir||H83009 probable transporter PA5099 [imported] - Pseudomonas... 122 1e-26 pir||B83591 probable transporter PA0443 [imported] - Pseudomonas... 120 4e-26 pir||E83590 cytosine permease PA0438 [imported] - Pseudomonas ae... 119 5e-26 emb|CAC11736.1| (AL445064) purine-cytosine permease related prot... 118 2e-25 pir||E70081 purine-cytosine permease homolog yxlA - Bacillus sub... 110 3e-23 sp|P25525|CODB_ECOLI CYTOSINE PERMEASE >gi|78382|pir||S22661 cyt... 109 6e-23 pir||E42594 hypothetical protein ORF5 hyuC 3'-region, hyuE 5'-re... 108 1e-22 gb|AAK41877.1| Cytosine permease (codB) [Sulfolobus solfataricus] 106 5e-22 pir||A83387 probable transporter (membrane subunit) PA2073 [impo... 106 7e-22 pir||T35663 probable transmembrane protein - Streptomyces coelic... 103 3e-21 gb|AAG02128.1|AF146701_4 (AF146701) permease homolog HyuP [Arthr... 99 1e-19 sp|P94575|YWOE_BACSU HYPOTHETICAL 54.0 KD PROTEIN IN NRGA-USD IN... 83 7e-15 gi|6320902 purine-cytosine permease; Fcy21p [Saccharomyces cerev... 77 3e-13 pir||T28687 hypothetical protein - Streptomyces coelicolor >gi|3... 77 4e-13 gb|AAG02126.1|AF146701_2 (AF146701) transport protein homolog [A... 77 4e-13 pir||S50563 hypothetical protein YER060w - yeast (Saccharomyces ... 76 5e-13 sp|Q01266|YHYC_PSESN HYPOTHETICAL PROTEIN IN HYUC 3'REGION (ORF ... 76 7e-13 emb|CAC12338.1| (AL445066) purine-cytosine permease related prot... 76 7e-13 pir||T48383 uracil transporter-like protein - Arabidopsis thalia... 76 9e-13 gb|AAA25848.1| (M72717) ORF 5 [Pseudomonas sp.] 75 1e-12 sp|P75712|ALLP_ECOLI PUTATIVE ALLANTOIN PERMEASE (ALLANTOIN TRAN... 72 1e-11 emb|CAA36040.1| (X51751) cytosine-purine permease (AA 1-533) [Sa... 72 1e-11 gi|6320897 purine-cytosine permease; Fcy2p [Saccharomyces cerevi... 70 4e-11 >pir||F75087 purine-cytosine permease related PAB1643 - Pyrococcus abyssi (strain Orsay) >gi|5458515|emb|CAB50003.1| (AJ248286) PURINE-CYTOSINE PERMEASE related [Pyrococcus abyssi] Length = 414 Score = 823 bits (2103), Expect = 0.0 Identities = 414/414 (100%), Positives = 414/414 (100%) Query: 1 MEEIKPVKEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAV 60 MEEIKPVKEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAV Sbjct: 1 MEEIKPVKEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAV 60 Query: 61 MSLIAIEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPG 120 MSLIAIEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPG Sbjct: 61 MSLIAIEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPG 120 Query: 121 TYYAWVIVLGILVTAWTIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPG 180 TYYAWVIVLGILVTAWTIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPG Sbjct: 121 TYYAWVIVLGILVTAWTIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPG 180 Query: 181 TGGLSLLIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFLGALSN 240 TGGLSLLIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFLGALSN Sbjct: 181 TGGLSLLIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFLGALSN 240 Query: 241 VAMGKEDPISLIAAYGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVLLV 300 VAMGKEDPISLIAAYGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVLLV Sbjct: 241 VAMGKEDPISLIAAYGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVLLV 300 Query: 301 GTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADESIRAPG 360 GTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADESIRAPG Sbjct: 301 GTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADESIRAPG 360 Query: 361 IIAWVIGFILYLSLTMESLIGISVPVLSQIGNEIGASIPVFLITMVLYYILSRR 414 IIAWVIGFILYLSLTMESLIGISVPVLSQIGNEIGASIPVFLITMVLYYILSRR Sbjct: 361 IIAWVIGFILYLSLTMESLIGISVPVLSQIGNEIGASIPVFLITMVLYYILSRR 414 >pir||A71058 probable cytosine permease - Pyrococcus horikoshii >gi|3257576|dbj|BAA30259.1| (AP000005) 422aa long hypothetical cytosine permease [Pyrococcus horikoshii] Length = 422 Score = 757 bits (1933), Expect = 0.0 Identities = 364/412 (88%), Positives = 397/412 (96%) Query: 1 MEEIKPVKEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAV 60 M++IKPVKE+IFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLK+ALAIIILGHLLGNAV Sbjct: 1 MQDIKPVKERIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKQALAIIILGHLLGNAV 60 Query: 61 MSLIAIEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPG 120 MSLIAIEGQETGLPTMVLSRGPLGGKGS+LPS LNYLQLIGWTAIMLIVGARALDVIFPG Sbjct: 61 MSLIAIEGQETGLPTMVLSRGPLGGKGSILPSLLNYLQLIGWTAIMLIVGARALDVIFPG 120 Query: 121 TYYAWVIVLGILVTAWTIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPG 180 TY+AWVIVLG+LVT WT+VGPERW WLEKLSV+LL +LS WLLYVIFSKYSFSELWNKPG Sbjct: 121 TYFAWVIVLGVLVTVWTLVGPERWGWLEKLSVILLAILSGWLLYVIFSKYSFSELWNKPG 180 Query: 181 TGGLSLLIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFLGALSN 240 TGGL LLIALDLVIAMPLSWAPTIADYSRFAKS++DAAWGTYLGHL GSAFCYFLGALSN Sbjct: 181 TGGLPLLIALDLVIAMPLSWAPTIADYSRFAKSKSDAAWGTYLGHLAGSAFCYFLGALSN 240 Query: 241 VAMGKEDPISLIAAYGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVLLV 300 VAMGKEDPISLIAAYGLGIPAMLIVL+STLNTTFMDIYSASITWKN+NPKA+LKTQ+L+V Sbjct: 241 VAMGKEDPISLIAAYGLGIPAMLIVLVSTLNTTFMDIYSASITWKNVNPKASLKTQILIV 300 Query: 301 GTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADESIRAPG 360 GTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMI DYF+V+++YDA +LLA++ IR PG Sbjct: 301 GTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMIADYFMVRKKYDANELLANQRIRIPG 360 Query: 361 IIAWVIGFILYLSLTMESLIGISVPVLSQIGNEIGASIPVFLITMVLYYILS 412 I+AW++GF LY+S+TMESLIG+ VPVLS +G+ IGASIPVFLIT+VLYYILS Sbjct: 361 IVAWIVGFALYISMTMESLIGVPVPVLSPLGDRIGASIPVFLITLVLYYILS 412 >pir||G82032 probable permease NMA0365 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7379117|emb|CAB83666.1| (AL162752) putative permease [Neisseria meningitidis Z2491] Length = 437 Score = 226 bits (571), Expect = 3e-58 Identities = 138/379 (36%), Positives = 205/379 (53%), Gaps = 18/379 (4%) Query: 20 IWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTMVLS 79 IWFGA IA I G LL P L + LA ++LGH +G A+ A G TG +M Sbjct: 17 IWFGAAVSIAEISTGTLLAP-LGWQRGLAALLLGHAVGGALFFAAAYIGALTGRSSMESV 75 Query: 80 RGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALD----VIFPGTYYAW-VIVLGILVT 134 R G +GSVL S N LQL GWTA+M+ GA V++ G + W + G L+ Sbjct: 76 RLSFGKRGSVLFSVANMLQLAGWTAVMIYAGATVSSALGKVLWDGESFVWWALANGALIV 135 Query: 135 AWTIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPGTGGLSLLIALDLVI 194 W + G + L+ +S++L+ + +WL +FS + + G+S A++L Sbjct: 136 LWLVFGARKTGGLKTVSMLLMLLAVLWLSAEVFSTAGSTAA---QVSDGMSFGTAVELSA 192 Query: 195 AMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFLGALSNVAMGKEDPISLIAA 254 MPLSW P ADY+R A+ A L + + + Y LG + + G+ D ++ Sbjct: 193 VMPLSWLPLAADYTRHARRPFAATLTATLAYTLTGCWMYALGLAAALFTGETDVAKILLG 252 Query: 255 YGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVLLVGTLGTLLALVFPVD 314 GLG +L V++ST+ TTF+D YSA ++ NI+ K + + V +GTLLA++ PV Sbjct: 253 AGLGAAGILAVVLSTVTTTFLDAYSAGVSANNISAKLSEIPIAVAVAVVGTLLAVLLPVT 312 Query: 315 KYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADESIRAPGIIAWVIGFILY--- 371 +YE FLLLIG F P+AA++I D+F++KR + E G++ W+ GFILY Sbjct: 313 EYENFLLLIGSVFAPMAAVLIADFFVLKRREEI------EGFDFAGLVLWLAGFILYRFL 366 Query: 372 LSLTMESLIGISVPVLSQI 390 LS ES IG++ PV+S + Sbjct: 367 LSSGWESSIGLTAPVMSAV 385 >pir||G81010 conserved hypothetical protein NMB2067 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7227329|gb|AAF42386.1| (AE002556) conserved hypothetical protein [Neisseria meningitidis MC58] Length = 407 Score = 220 bits (555), Expect = 2e-56 Identities = 136/379 (35%), Positives = 203/379 (52%), Gaps = 18/379 (4%) Query: 20 IWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTMVLS 79 IWFGA IA I G LL P L + LA ++LGH +G A+ A G TG +M Sbjct: 17 IWFGAAVSIAEISTGTLLAP-LGWQRGLAALLLGHAVGGALFFAAAYIGALTGRSSMESV 75 Query: 80 RGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALD----VIFPGTYYAW-VIVLGILVT 134 R G +GSVL S N LQL GWTA+M+ GA V++ G + W + G L+ Sbjct: 76 RLSFGKRGSVLFSVANMLQLAGWTAVMIYAGATVSSALGKVLWDGESFVWWALANGALIV 135 Query: 135 AWTIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPGTGGLSLLIALDLVI 194 W + G + L+ +S++L+ + +WL +FS + + G+S A++L Sbjct: 136 LWLVFGARKTGGLKTVSMLLMLLAVLWLSAEVFSTAGSTAA---QVSDGMSFGTAVELSA 192 Query: 195 AMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFLGALSNVAMGKEDPISLIAA 254 MPLSW P ADY+R A+ A L + + + Y LG + + G+ D ++ Sbjct: 193 VMPLSWLPLAADYTRHARRPFAATLTATLAYTLTGCWMYALGLAAALFTGETDVAKILLG 252 Query: 255 YGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVLLVGTLGTLLALVFPVD 314 GLG +L V++ST+ TTF+D YSA + NI+ + + V +GT+LA++ PV Sbjct: 253 AGLGAAGILAVVLSTVTTTFLDAYSAGASANNISARFAETPVAVGVTLIGTVLAVMLPVT 312 Query: 315 KYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADESIRAPGIIAWVIGFILY--- 371 +YE FLLLIG F P+AA++I D+F++KR + E G++ W+ GFILY Sbjct: 313 EYENFLLLIGSVFAPMAAVLIADFFVLKRREEI------EGFDFAGLVLWLAGFILYRFL 366 Query: 372 LSLTMESLIGISVPVLSQI 390 LS ES IG++ PV+S + Sbjct: 367 LSSGWESSIGLTAPVMSAV 385 >dbj|BAB05601.1| (AP001513) cytosine permease [Bacillus halodurans] Length = 445 Score = 150 bits (374), Expect = 4e-35 Identities = 112/385 (29%), Positives = 190/385 (49%), Gaps = 16/385 (4%) Query: 3 EIKPVKEKIFDFWSNFS-IWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVM 61 E PV E+ W + S +W G ++ G L L+L +A+ +LG L+ + V Sbjct: 14 ERMPVPEEHRKGWIHLSLVWLGIAIALSATVLGGTLGGGLTLGQAILATMLGALVLSIVS 73 Query: 62 SLIAIEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPGT 121 + ++ G TGL T ++S+ LG G+ + S + + L GW + L + + + Sbjct: 74 ACCSVVGARTGLSTGLVSKFALGTYGAYVVSAVIAIALFGWFGVQLDLFGTSFQQVIMNV 133 Query: 122 Y------YAWVIVLGILVTAWTIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSEL 175 + VI+ GIL+T+ ++G + L K +V L+G+L + L+ + S +S++ Sbjct: 134 FGLNIPKILLVIIGGILMTSTAVIGYKAIEKLSKAAVPLMGLLLIASLWRVLSSQQWSDV 193 Query: 176 WNKPGTGG-LSLLIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYF 234 N P TG L L IA+ LVI A D +R+AK+ DA G++ G LVG + Sbjct: 194 VNAPMTGDPLPLGIAISLVIGSFAVGAVIGPDIARYAKTPKDAVIGSFSGFLVGFSAVLI 253 Query: 235 LGALSNVAMGKEDPISLIAAYGLGIPAMLIVLISTLNTTFMDIYSA----SITWKNINPK 290 + A+ A G+ D ++++ G G AMLI++++ T ++YSA S+ +K+I PK Sbjct: 254 VAAILAKATGEVDIVAIMLGLGWGTFAMLILILAQWTTNDNNLYSAALGFSVIFKSI-PK 312 Query: 291 ANLKTQVLLVGTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKL 350 A L + G +GTL+A+ D + FL+ + P+ I + DY L K +Y L Sbjct: 313 AKL---TIGAGIIGTLMAVFGIYDNFIPFLIFLSALIPPIGGIYVADYLLNKGKYSFANL 369 Query: 351 LADESIRAPGIIAWVIGFILYLSLT 375 + I G+ W+I + T Sbjct: 370 SNMKMINPIGVTTWMIASLFAFMTT 394 >pir||H83009 probable transporter PA5099 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9951394|gb|AAG08484.1|AE004922_9 (AE004922) probable transporter [Pseudomonas aeruginosa] Length = 480 Score = 122 bits (302), Expect = 1e-26 Identities = 113/438 (25%), Positives = 205/438 (46%), Gaps = 32/438 (7%) Query: 6 PVKEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLS-LKEALAIIILGHLLGNAVMSLI 64 P E+ +S F++W GA+ I I GAL + +L ++LG LLG AVM+L Sbjct: 20 PANERHGRLYSQFTLWLGANLQITAIVTGALAVVLGGDVFWSLVGLLLGQLLGGAVMALH 79 Query: 65 AIEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPGTYYA 124 A +G GLP M+ SR G G+ +P L L +G+TA ++ +A+ + + A Sbjct: 80 AAQGPRLGLPQMISSRVQFGVYGACIPIALVCLMYLGFTATGTVLSGQAIGQLTGLSDSA 139 Query: 125 WVIVLGILVTAWTIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPGTGGL 184 + + + T++G + +++ VL + +L + +L Sbjct: 140 GIFIFAAFIVLVTVLGYRVIHIIGRIASVLGIIAFAYLFSRLMLLSDIGDLLAIRHFSWA 199 Query: 185 SLLIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTY----LGHLVGSAFCYFLG---- 236 S L+A+ L + +++ P +ADYSR+ + + ++W T+ LG ++G+ LG Sbjct: 200 SFLLAVSLAASWQIAFGPYVADYSRYLPA-STSSWKTFLAVGLGSVLGAQASMVLGVFSA 258 Query: 237 ALSNVAMGKEDPISLIAAYGLGIPAMLI--------VLISTLNT--TFMDIYS--ASITW 284 AL+N + ++ G A L+ V ISTLN+ +FM I + +S+ Sbjct: 259 ALANGQFAGREVAYIVGLGSSGTVAALLYFSIAFGKVTISTLNSYGSFMCIATIISSVRG 318 Query: 285 KNINPKANLKTQVLLVGTLGTLLALVFP---VDKYEAFLLLIGGAFVPLAAIMITDYFLV 341 + + VL + TL+AL+ + +++F+L + F P +A+ + DY+ + Sbjct: 319 QLEITRVQRLFFVLAIVGASTLIALLGQHSFLAAFKSFILFLLTFFTPWSAVNLVDYYFI 378 Query: 342 KREYDAEKLLADESIR-----APGIIAWVIGFILYLSLTMESLIGISVPVLSQIGNEIGA 396 RE LAD R PGI + +G ++ + +L + P++ +G + Sbjct: 379 TRERYDVPALADPDGRYGRWNLPGIAVYTLGVLVQMPFLATTL--YTGPMVEHLGGVDIS 436 Query: 397 SIPVFLITMVLYYILSRR 414 I L+ VLYY+++RR Sbjct: 437 WIIGLLVPAVLYYLVARR 454 >pir||B83591 probable transporter PA0443 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9946301|gb|AAG03832.1|AE004481_8 (AE004481) probable transporter [Pseudomonas aeruginosa] Length = 496 Score = 120 bits (297), Expect = 4e-26 Identities = 115/411 (27%), Positives = 186/411 (44%), Gaps = 55/411 (13%) Query: 7 VKEKIFDFWSNFSIWFGADFGIAVIWAGALLTPY--LSLKEALAIIILGHLLGNAVMSLI 64 V+++ ++ W ++W G + G +LT Y LS+ EAL I+L +L+ ++L Sbjct: 38 VEQRTWNRWHITALWIGMSICVPTYTLGGVLTAYFGLSVGEALLAILLANLVVLIPLTLN 97 Query: 65 AIEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPGTYYA 124 A G G+P VL R G GS +P + + GW I + G A+ + + A Sbjct: 98 AFAGTRYGIPFPVLLRASFGIIGSNVPCLIRAVVACGWFGIQTLFGGLAIHLFLGSIFPA 157 Query: 125 WVI------VLGIL----VTAWTIV-GPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFS 173 W V+G L + W ++ G E +WLE LS LL ++ + LL S S Sbjct: 158 WKALGGTGEVIGFLLFWGLNLWVVLRGAESIKWLETLSAPLLVLVGLGLLVWALPHISVS 217 Query: 174 ELWNKP--GTGGLSL----LIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLV 227 EL +P G S+ + L ++ + + I D+SR+A+S+ D LG + Sbjct: 218 ELLAQPPKRPEGASVTGYFMAGLTAMVGFWATLSLNIPDFSRYARSQKD----QILGQIF 273 Query: 228 GSAFCYFLGALSNVAMGK----------EDPISLIA---AYGLGIPAMLIVLISTLNT-T 273 G FL A V M DP+SLI + G AM +++++TL+T T Sbjct: 274 GLPLTMFLFAALGVVMTAASASLVGETVSDPVSLIGHIPSPGWVAVAMALIIVATLSTNT 333 Query: 274 FMDIYSASITWKNINPKANLKTQVL--------------LVGTLGTLLALVFPVDKYEAF 319 +I S + ++NI PK +T+ + L+ LG +++ + Y + Sbjct: 334 AANIVSPTNDFQNIAPKLIGRTRAVWLTGFIGLALMAHELLKKLGWIVSDLSLESVYSNW 393 Query: 320 LLLIGGAFVPLAAIMITDYFLVKRE-YDAEKLLADESIRA---PGIIAWVI 366 LL P+A IM+ DYFLV+R+ D L D+ A PG A+ + Sbjct: 394 LLGYSSLLGPIAGIMVVDYFLVRRQRLDLAGLYRDDVYPAWNWPGFAAFAV 444 >pir||E83590 cytosine permease PA0438 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9946296|gb|AAG03827.1|AE004481_3 (AE004481) cytosine permease [Pseudomonas aeruginosa] Length = 416 Score = 119 bits (296), Expect = 5e-26 Identities = 104/397 (26%), Positives = 176/397 (44%), Gaps = 29/397 (7%) Query: 20 IWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTMVLS 79 + G F A +W G L LS + ++LG+L+ +++ G TGL T +L+ Sbjct: 26 VMLGLTFFSASMWTGGTLGTGLSYDDFFLAVLLGNLMLGLYTAILGFIGARTGLSTHLLA 85 Query: 80 RGPLGGKGSVLPSFLNYLQLIGWTAIML------IVGARALDVIFPGTYYAWVIVLGILV 133 G KGS LPS L +GW + + + A LDV ++V G L+ Sbjct: 86 HYSFGSKGSWLPSALLGGTQVGWFGVGVAMFAIPVAKATGLDVNL------LILVSGALM 139 Query: 134 TAWTIVGPERWRWLEKLSV---VLLGVLSVWLLYVIFSKYSFSELWNKPGTGGLSLLIAL 190 T G L ++V V+LG SVWL + + L + LSL A+ Sbjct: 140 TLTVFFGIAGLTLLSAIAVPAIVVLGSYSVWL--AVRDAGGLAALQQVTPSAPLSLSTAI 197 Query: 191 DLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFLGALSNVAMGKEDPIS 250 LV+ +S AD+ RF +S A + +G++ + GA A+GK D Sbjct: 198 ALVVGSFVSAGTLTADFVRFGRSARTAVVVCLVAFFLGNSLMFIFGAAGAAAVGKSDISD 257 Query: 251 LIAAYGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVLLVGTLGTLLALV 310 ++ A GL IPA+L++ ++ T +Y++ + + NI ++ + +L G LGTL AL Sbjct: 258 VMIAQGLLIPAILVLGLNIWTTNDNALYASGLGFANITGLSS-RFLAMLNGALGTLAAL- 315 Query: 311 FPVDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADESIRAPGIIAWVIGFIL 370 + + + +L + A P+ ++I DY +R Y ++I I+A G Sbjct: 316 WLYNHFVGWLTFLSAAIPPIGGVIIADYLSRRRRYRQHPCADIQAINWAAILAVACG--- 372 Query: 371 YLSLTMESLIGISVPVLSQIGNEIGASIPVFLITMVL 407 + G +P + + +GA+I L+ +L Sbjct: 373 -------TAAGHWLPGIVPVNAVLGAAIAYLLLNPLL 402 >emb|CAC11736.1| (AL445064) purine-cytosine permease related protein [Thermoplasma acidophilum] Length = 460 Score = 118 bits (292), Expect = 2e-25 Identities = 104/420 (24%), Positives = 192/420 (44%), Gaps = 32/420 (7%) Query: 16 SNFSIWFGADFGIAVIWAGALLTPYLSLKEALAIIIL--GHLLGNAVMSLIAIEGQETGL 73 S F IWF ++ + G + YL L +I+ + G + G +++ ++ G + Sbjct: 37 SMFYIWFASNLTVGDFAVG-FIPVYLGLPILYSIVAIAVGTIAGGIMLAYMSQLGAVYRV 95 Query: 74 PTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPGTYYAWVIVLGILV 133 P M + R P G G L S L + GW + +I+ + A+ + YYA V+++ +V Sbjct: 96 PQMYMGRAPFGTVGGSLLSILQWGNTAGWLTVNVILASLAIYQMVKIPYYAIVLLIVAIV 155 Query: 134 TAWTIVGPERWRWLEKLSVVLLGVLSVWL-LYVIFS----KYSFSELWNKPGTGGLSLLI 188 +VG R LE+ +LG+L V+L L++I S Y + + ++ P G++ Sbjct: 156 ALTALVGYRAIRILERSMSYVLGLLFVFLVLFLIHSHASISYQYVDSFSIPAAFGITFAS 215 Query: 189 ALDLVIAMPLSWAPTIADYSRFAKSRADAA---WGTYLGHLVGSAFCYFLGALSNVAMGK 245 A + +SW P ADYSR S + + T LG ++ S F +G + + A G Sbjct: 216 AFSYI----MSWGPYAADYSRHVSSSKPSKSIFYYTLLGSVIASVFAEIVGLMVSAASGN 271 Query: 246 ------EDPISLIAAYGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVLL 299 D +++ Y + ++ + + ++ +++YS S+ + +I KA+ + + Sbjct: 272 PSGSPAADLANVMNKY--AVIGLIALFLGGISANAINLYSNSLAFLSIGFKAHRWVAIAV 329 Query: 300 VGTLGTLLALV---FPVDKYEAFLLLIGGAFVPLAAIMITDYFLVK--REYDAEKLLADE 354 LL ++ YE FL ++ P IMI +F++K R + E L Sbjct: 330 ASVFSLLLGIIGFFRFYGFYETFLFILDYWITPWIGIMIAHFFILKRLRHQEFEDL---P 386 Query: 355 SIRAPGIIAWVIGFILYLSLTMESLIGISVPVLSQIGNEIGASIPVFLITMVLYYILSRR 414 I PGI A++I + + + I I++P+ S + + F M++Y LSR+ Sbjct: 387 KIVKPGIYAYIISIAVSIPFMSPAGI-INMPLASMLHGVDISYFVSFFSAMIIYLYLSRK 445 >pir||E70081 purine-cytosine permease homolog yxlA - Bacillus subtilis >gi|1783255|dbj|BAA11732.1| (D83026) homologous to purine-cytosine permease (SwissProt:FCY2_YEAST); hypothetical [Bacillus subtilis] >gi|2636406|emb|CAB15897.1| (Z99123) similar to purine-cytosine permease [Bacillus subtilis] Length = 457 Score = 110 bits (273), Expect = 3e-23 Identities = 113/423 (26%), Positives = 187/423 (43%), Gaps = 32/423 (7%) Query: 18 FSIWFGADFGIAVIWAGAL-LTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTM 76 F +WFGA+ I + G + + L+L ++A II G L+G M+ + +G + G+P M Sbjct: 24 FPVWFGANMHITTLVTGTIPVAMGLNLFWSVAAIICGTLIGAIFMASHSAQGPQLGIPQM 83 Query: 77 VLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALD--VIFPGTYYAWVIVLGILVT 134 + SR G G++LP FL +G+ A I+ A L V PG++ +I L + Sbjct: 84 IQSRAQFGVIGAILPLFLVMFIYLGFFASSTILAAGTLSSFVPIPGSWS--IIGLSAVCF 141 Query: 135 AWTIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPGTGGLSL-LIALDLV 193 TI G + ++K+ + +IF + W PG L + L+A+ V Sbjct: 142 LLTIFGHDLIHKMQKILSWTSFAVFFAATILIFQLPIPAGSW-IPGAIDLPIFLVAVSAV 200 Query: 194 IAMPLSWAPTIADYSRFAKSRADAA---WGTYLGHLVGSAFCYFLGALSNVAM---GKED 247 L++AP +ADYSR+ + A+ W +Y G V S + LGAL ++ Sbjct: 201 ATWQLAYAPYVADYSRYLPVKTPASKTFWYSYAGTSVSSIWMMLLGALLTTSLPDFTANS 260 Query: 248 PISLIAAYG-LGIPAMLIVLISTLNTTFMDIYSASI-TWKNINPKANLKTQ--------- 296 ++ +G ++IVL + ++Y A + T + P LK Sbjct: 261 GSQIVQLFGPFSFIMLIIVLFGQMAINVFNLYGAFMSTTTTLEPFLKLKVTPKVRIIMIL 320 Query: 297 -VLLVGTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADES 355 V LVGT+ +LL ++ + F+ I +P AI + DY+ V+ K + D Sbjct: 321 GVTLVGTVLSLLGQSNFMELFLNFIFFISYFLIPWTAINLVDYYFVRHGKYQVKAMFD-- 378 Query: 356 IRAP-GIIAWVIGFILYLSLTME-SLIGISV---PVLSQIGNEIGASIPVFLITMVLYYI 410 + P G + W+ LS+ +E I S P+ G A I + VLYY+ Sbjct: 379 VNGPYGKVNWITTIAFVLSILLEIPFINTSFYIGPLAKMFGGGDIAWIIGLAVPSVLYYV 438 Query: 411 LSR 413 L + Sbjct: 439 LMK 441 >sp|P25525|CODB_ECOLI CYTOSINE PERMEASE >gi|78382|pir||S22661 cytosine transport protein - Escherichia coli >gi|581051|emb|CAA45195.1| (X63656) cytosine permease [Escherichia coli] >gi|1657532|gb|AAB18060.1| (U73857) cytosine permease [Escherichia coli] >gi|1786530|gb|AAC73439.1| (AE000140) cytosine permease/transport [Escherichia coli K12] >gi|1586752|prf||2204355A cytosine permease [Escherichia coli] Length = 419 Score = 109 bits (270), Expect = 6e-23 Identities = 89/351 (25%), Positives = 157/351 (44%), Gaps = 7/351 (1%) Query: 20 IWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTMVLS 79 + G F A +W G L LS + +++G+LL S + G +TGL T +L+ Sbjct: 26 VMLGLTFFSASMWTGGTLGTGLSYHDFFLAVLIGNLLLGIYTSFLGYIGAKTGLTTHLLA 85 Query: 80 RGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPGTYYAWVIVLGILVTAWTIV 139 R G KGS LPS L +GW + + + A + + V G+L+T Sbjct: 86 RFSFGVKGSWLPSLLLGGTQVGWFGVGVAMFAIPVGKATGLDINLLIAVSGLLMTVTVFF 145 Query: 140 GPERWRWLEKLSV---VLLGVLSVWLLYVIFSKYSFSELWNKPGTGGLSLLIALDLVIAM 196 G L ++V LG SVWL + L L +AL LV+ Sbjct: 146 GISALTVLSVIAVPAIACLGGYSVWL--AVNGMGGLDALKAVVPAQPLDFNVALALVVGS 203 Query: 197 PLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFLGALSNVAMGKEDPISLIAAYG 256 +S AD+ RF ++ A + +G++ + GA A+G D ++ A G Sbjct: 204 FISAGTLTADFVRFGRNAKLAVLVAMVAFFLGNSLMFIFGAAGAAALGMADISDVMIAQG 263 Query: 257 LGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVLLVGTLGTLLALVFPVDKY 316 L +PA++++ ++ T +Y++ + + NI ++ KT ++ G +GT+ AL + + + Sbjct: 264 LLLPAIVVLGLNIWTTNDNALYASGLGFANITGMSS-KTLSVINGIIGTVCAL-WLYNNF 321 Query: 317 EAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADESIRAPGIIAWVIG 367 +L + A P+ ++I DY + +R Y+ S+ I+A +G Sbjct: 322 VGWLTFLSAAIPPVGGVIIADYLMNRRRYEHFATTRMMSVNWVAILAVALG 372 >pir||E42594 hypothetical protein ORF5 hyuC 3'-region, hyuE 5'-region - Pseudomonas sp. plasmid pHN671 Length = 456 Score = 108 bits (267), Expect = 1e-22 Identities = 106/443 (23%), Positives = 199/443 (43%), Gaps = 57/443 (12%) Query: 8 KEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIE 67 KE+ + F +W G + A L P LS + + ILG+L+ +++L+ Sbjct: 6 KERNMSSIAYFILWVGIAVQLVTPITAAQLYPALSPLQIIIACILGNLIVAILLTLLGDI 65 Query: 68 GQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFP-----GTY 122 G G+P V R G G+ +P + + + W +GA ALD I Sbjct: 66 GVRYGIPYAVYIRASFGYLGAHIPGIVRAVPAVFWFGFQTWMGAYALDAIMEMLTGYSNL 125 Query: 123 YAWVIVLGILVTAWTIVGPE---RWRWLEKLSVVLLGVLSVWLLYVIFSKY-SFSELWNK 178 +I+ G++ T +G E ++ WL S++++G+ + +Y++ + +FSE+++ Sbjct: 126 TLLIILFGVVQIINTAMGMEAITKFEWLASPSILIIGI--ILQVYIMKQHHLTFSEIFSH 183 Query: 179 PGTGGLSLLIALDLVIAMPLSWAPTIADYSRFAKSRADAA---W-----GTYLGH---LV 227 G GG+S+ A+ +++ ++ A D++RF K++ ++ W G++ H L+ Sbjct: 184 GGDGGVSMGYAVVVMMGTYITMALNAPDFTRFLKTKTGSSEPNWWKVNKGSFWAHTFGLI 243 Query: 228 GSAFCY-FLGALSNVAMGKEDPI-SLIAAYGLGIPAMLIVLISTLNTTFMDIYSASITWK 285 GS + +G S VA G +PI ++I G P +LIV ++ + + +S +I+ Sbjct: 244 GSMLLFTIIGLTSGVATGTWNPIDAMIQTMGKDNPFLLIVCLAFV---ILAQWSTNISAN 300 Query: 286 NINP----------KANLKTQVLLVGTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMI 335 + P K + ++ G +G L+ + L++I P+ IM Sbjct: 301 LLPPGYIIVNLFPRKISFPMGAIIAGIIGLLIQPWNYAEFVPQILMVITATLAPIVGIMF 360 Query: 336 TDYFLVKREYDAEKLLADESIRAPGIIAW-----VIGFILYLSLTMESLIGISVPVLSQI 390 TDY+L+++ +L DE + G + I Y+ G+SV + Sbjct: 361 TDYYLLRK----RRLNLDELYKVDGQYKYWKNVNPAAIIAYIP------SGLSVLLFPDY 410 Query: 391 GNEIGASIPVFLITMVLYYILSR 413 G + LI+MVLYY L + Sbjct: 411 G-----FVTALLISMVLYYTLMK 428 >gb|AAK41877.1| Cytosine permease (codB) [Sulfolobus solfataricus] Length = 453 Score = 106 bits (262), Expect = 5e-22 Identities = 100/421 (23%), Positives = 184/421 (42%), Gaps = 25/421 (5%) Query: 8 KEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIE 67 K+ + F++ F ++ IAVIWAG L L+ +A+ ++ G ++ + SL A Sbjct: 21 KDSRYGFFNVFLVFSSVYGAIAVIWAGGALGYGLTFSQAIIAVLSGTVVLGILGSLTAAV 80 Query: 68 GQETGLPTMVLSRGPLGGKGSVLPSFL--NYLQLIGWTAIMLIVGARALDVIFPGTYYAW 125 G +GL T V+ R PLG G + L IGW A+ + + IFP + Sbjct: 81 GAYSGLSTYVMWRHPLGRWGGKIAGLLLITITTGIGWYAVETWLFGIVMSEIFPNNPFFS 140 Query: 126 VIVL----GILVTAWTIVGPERWRWLEKLSVVL-LGVLSVWLLYVIFSKYSFSELWNKPG 180 V V GIL+T T VG +L ++ + ++++ + V+ K F + Sbjct: 141 VGVAAIWGGILMTIMTYVGYRMLSFLSYFTIPFHIWLIAIGIAIVLALKGGFHTVMAAVP 200 Query: 181 TGGLSLLIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFLGALSN 240 T +SLL + I + + D SRFAKS DA + + + F G Sbjct: 201 TSHMSLLDGISATIGLYSAGTIISPDISRFAKSAKDAGYAWFAHIIFLYPFLILGGVAIV 260 Query: 241 VAMGKEDPISLIAAYGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVLLV 300 +A G + + G+G+ +LI++ ++YS S++ N+ P + ++ Sbjct: 261 LATGSYLITNAMLELGMGVGVLLIIVFGQFIINTDNLYSGSLSLVNLIPMRR-EIASVIN 319 Query: 301 GTLGTLLALVF------PVDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADE 354 G +GT +A + +E F+ L+G + I++ D+++VK+ + + Sbjct: 320 GVIGTAIAAYVGFSAGSSITPFENFISLLGDFLPAMGGIVLADFYIVKKYVNKIQDPHKR 379 Query: 355 SIRAPGIIAWVIGFILYLSLTMESLIG----ISVPVLSQIGNEIGASIPVFLITMVLYYI 410 P + I L+L + S+IG +P ++ + + FL +++YYI Sbjct: 380 YEFVPNNKYYNINIAGILALALGSIIGYFVNAGIPAINSL-------VTGFLSYIIIYYI 432 Query: 411 L 411 + Sbjct: 433 I 433 >pir||A83387 probable transporter (membrane subunit) PA2073 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9948083|gb|AAG05461.1|AE004634_4 (AE004634) probable transporter (membrane subunit) [Pseudomonas aeruginosa] Length = 476 Score = 106 bits (261), Expect = 7e-22 Identities = 106/440 (24%), Positives = 183/440 (41%), Gaps = 39/440 (8%) Query: 6 PVKEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKEALAI--IILGHLLGNAVMSL 63 P E+ W WF +F + + G P L L +I I+LG G M+ Sbjct: 21 PRHERHGKVWHQAPFWFTGNFVLTTMVTG-FTGPALGLGALYSILAIVLGVCFGTFFMAF 79 Query: 64 IAIEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPGTYY 123 A +G GLP M+ SR G +G+++P IG+ +I+ A++ + PG Sbjct: 80 HANQGPRMGLPQMIQSRAQFGLRGAIVPFAAVVFVYIGFNVFNVILATDAINTVLPGHRA 139 Query: 124 AWVIVLGILVTAWTIVGPER----WRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKP 179 W ++L + IVG + RWL + + + GVL+V L S + + L P Sbjct: 140 PWYVLLIGVAVLLAIVGHDLLHTVQRWLTYVMIAVFGVLTVSALR---SLEADAALGGTP 196 Query: 180 GTGGLSLLIALDLVIAMPLSWAPTIADYSRF----AKSRADAAWGTYLGHLVGSAFCYFL 235 + L+ L +S+A ++DYSR+ +R W TYLG + + L Sbjct: 197 AFSWSAFLVQLSAAAGYQISYAVYVSDYSRYLPHETPTRKVIFW-TYLGAAGSALWLMSL 255 Query: 236 GALSNVAMGKEDPISLIAAYG-------------LGIPAMLIVLISTLNTTFMDIYSASI 282 GA A+ D I + G + +PA++ ++ + SA Sbjct: 256 GAFLASALPAPDAIGSVREVGNRLYPGFGTFTVLIAVPALVGIMAVNCYGAMLTSLSAID 315 Query: 283 TWKNINPKANLK-TQVLLVGTLGTLLALVFP---VDKYEAFLLLIGGAFVPLAAIMITDY 338 ++ + P NL+ T + ++ + +AL P + + F+LL+ VP A+ + D+ Sbjct: 316 AFRKVTPTLNLRVTGIGVIALVVFGVALSIPESYLGSFNTFVLLMLYFLVPWTAVNLVDF 375 Query: 339 FLVKR-EYDAEKLLADESIRA----PGIIAWVIGFILYLSLTMESLIGISVPVLSQIGNE 393 + V+ Y ++ E I PG+ A++ G L + SL S P +G Sbjct: 376 YFVRNGHYAISEIFNPEGIYGHWGRPGLSAYLAG--LLAMVPFMSLSFYSGPFAVALGGA 433 Query: 394 IGASIPVFLITMVLYYILSR 413 A + L+ +Y + R Sbjct: 434 DVAFVVGLLVAGAVYAFMCR 453 >pir||T35663 probable transmembrane protein - Streptomyces coelicolor >gi|4007738|emb|CAA22422.1| (AL034447) putative transmembrane protein [Streptomyces coelicolor A3(2)] Length = 485 Score = 103 bits (255), Expect = 3e-21 Identities = 109/435 (25%), Positives = 183/435 (42%), Gaps = 43/435 (9%) Query: 18 FSIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGH--LLGNAVMSLIAIEGQETGLPT 75 F W GA+ + ++ GA L L A+++ G ++ ++ LI I G+ G P Sbjct: 32 FPTWVGANISVLLLTMGASLVVAYRLNFWQALVVAGAAPVVSYGLVGLIGIAGKRGGAPG 91 Query: 76 MVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARA----LDVIF---PGTYYAWVIV 128 M LSR G +G++LP L ++ GW I + GA A LD++F + V + Sbjct: 92 MALSRAVFGQRGNLLPGSLIWVARWGWETINAVTGAYALLTVLDIVFGIRANSVLDMVTL 151 Query: 129 LGILVTAWTI--VGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPGTGGLSL 186 L +V + I +G + K + L G SV +L + +S ++++ ++ Sbjct: 152 LAFVVATFAISGLGINAVQKCNKYAAYLFGAFSVLVLGYLVVDTDWSAVFDRSAGSVAAM 211 Query: 187 LIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFL-----GALSNV 241 + + L+ A +SW P+ D++R+ A + +G VG A L GA+ V Sbjct: 212 ITGVGLIAAGGVSWIPSAPDFTRYLPRTASSK--GIVGVTVGGAGIVVLPMVLMGAVMAV 269 Query: 242 A----MGKEDPISL---IAAYGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLK 294 + DP+S I + +P +LI LI L M +YSA T + + K Sbjct: 270 STPDLASAADPVSFLGEILPTWIAVPYLLIALIGMLLINSMSMYSAGFTAQTLGFKVPRH 329 Query: 295 TQV-------LLVGTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDA 347 V L+ G + L+A F + + AFL L+ AF + D L REYD Sbjct: 330 WAVSVNAVISLVFGGVLMLVATSF-MGSFIAFLSLLAVAFSAWVGVFGAD-MLRGREYDG 387 Query: 348 EKLLADESIRA---------PGIIAWVIGFILYLSLTMESLIGISVPVLSQIGNEIGASI 398 E L A ++AW +G L T + + +G + Sbjct: 388 EALADTGRTSAYWYRGGFSPAAVVAWAVGLAAGLMFTTSDWFTGPLATDNFVGEYGLGWV 447 Query: 399 PVFLITMVLYYILSR 413 +I+ +LY +L + Sbjct: 448 ATVVISALLYAVLPK 462 >gb|AAG02128.1|AF146701_4 (AF146701) permease homolog HyuP [Arthrobacter aurescens] Length = 478 Score = 98.7 bits (242), Expect = 1e-19 Identities = 93/378 (24%), Positives = 167/378 (43%), Gaps = 32/378 (8%) Query: 19 SIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTMVL 78 +IWF +A+ A LT + + + I G + V+ G+ V Sbjct: 34 AIWFAMAIQVAIFIAAGQLTASFQVWQVIVAIAAGCTIAVVVVFFTQSAAIRWGINFTVA 93 Query: 79 SRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFP-----GTYYAWVIVLGILV 133 +R P G +GS++P + L + W +GA ALD I WV++ G + Sbjct: 94 ARMPFGIRGSLIPIVVKALLSLFWFGFQTWLGALALDEITRILTGFSNLTLWVLIFGAVQ 153 Query: 134 TAWTIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSK--YSFSELWNKPG-TGGLSLLIAL 190 T G RW+ + +L + V+++Y++ + + E+ + G T G+ A+ Sbjct: 154 VVTTFYGISFIRWMNIFAAPVLLAMGVFMVYLMLNGAGVTLGEVMSMGGETPGMPFSTAV 213 Query: 191 DLVIAMPLSWAPTIADY----------SRFAKSRADAAWGT--YLGHLVGSAFCYFLGAL 238 + + ++ +I D SR + ++DA + + G + S F+GA Sbjct: 214 MIFVGGWIAVVVSIHDIVKECKVSPSESREGRVKSDAKYAAAQWWGMVPASVIFGFIGAA 273 Query: 239 SNVAMGKEDPISLIA------AYGLGIPAMLIVLISTLNTT-FMDIYSASITWKNINPKA 291 S V +G+ +P+ I + + I + VL++T +T ++ S + T + P+ Sbjct: 274 SMVLVGEWNPVFAITKVVGEVSVPMAILFQVFVLLATWSTNPAANLLSPAYTLCSTFPRV 333 Query: 292 -NLKTQVLLVGTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKL 350 + KT V++ G +G L+ D +FL ++ A PLA IMITDYFLV+R ++ Sbjct: 334 FSFKTGVIVSGAIGLLMMPWQFADTLNSFLNILASALGPLAGIMITDYFLVRR----GRV 389 Query: 351 LADESIRAPGIIAWVIGF 368 + R GI + GF Sbjct: 390 SLQDLYRTKGIYTYWHGF 407 >sp|P94575|YWOE_BACSU HYPOTHETICAL 54.0 KD PROTEIN IN NRGA-USD INTERGENIC REGION >gi|7430010|pir||H70064 permease homolog ywoE - Bacillus subtilis >gi|1684649|emb|CAB05378.1| (Z82987) unknown, similar to uracil permease from Schizosaccharomyces pombe [Bacillus subtilis] >gi|2636172|emb|CAB15664.1| (Z99122) similar to permease [Bacillus subtilis] Length = 490 Score = 82.7 bits (201), Expect = 7e-15 Identities = 113/458 (24%), Positives = 190/458 (40%), Gaps = 86/458 (18%) Query: 19 SIWFGADFGIAVI-WAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTMV 77 SIW G I G L+ LS + LAIII L+ ++L G + GLP V Sbjct: 35 SIWMGCIHNIPTYATVGGLIAIGLSPWQVLAIIITASLILFGALALNGHAGTKYGLPFPV 94 Query: 78 LSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPGTYYAWVIVLGILVTAWT 137 + R G G+ +P+ L I W I G+ AL+++ + W G + W Sbjct: 95 IIRASYGIYGANIPALLRAFTAIMWLGIQTFAGSTALNILLLNMWPGW----GEIGGEWN 150 Query: 138 IVGPER-------WRWLEKLSVVLLGVLS-----VW---LLYVIFSK------------- 169 I+G + W L V+ G+ S VW L+Y++F Sbjct: 151 ILGIHLSGLLSFVFFWAIHLLVLHHGMESIKRFEVWAGPLVYLVFGGMVWWAVDIAGGLG 210 Query: 170 ---------YSFSE-LWNKPGTGGLSLLIALDLVIAMPLSWAPTIADYSRFAKSRADAAW 219 ++FSE W P G++ +I + + + I D++RFA+++ + Sbjct: 211 PIYSQPGKFHTFSETFW--PFAAGVTGIIGIWATLIL------NIPDFTRFAETQKEQIK 262 Query: 220 GTYLGHLVGSAFCYFLGALSNVAMGKE--------DPISLIAAYG---LGIPAMLIVLIS 268 G + G + F F A V G + D + ++A + + + +++ + I+ Sbjct: 263 GQFYG--LPGTFALFAFASITVTSGSQVAFGEPIWDVVDILARFDNPYVIVLSVITLCIA 320 Query: 269 TLNTTF-MDIYSASITWKNINPK-ANLKTQVLLVGTLGTLLA---LVFPVDKYEAFLLLI 323 T++ +I S + N PK N K + L L+ AFL LI Sbjct: 321 TISVNVAANIVSPAYDIANALPKYINFKRGSFITALLALFTVPWKLMESATSVYAFLGLI 380 Query: 324 GGAFVPLAAIMITDYFLV-KREYDAEKLLAD-------ESIRAPGIIAWVIGFILYLSLT 375 GG P+A +M+ DYF++ KRE + L ++ + A ++G ++ Sbjct: 381 GGMLGPVAGVMMADYFIIRKRELSVDDLYSETGRYVYWKGYNYRAFAATMLGALI----- 435 Query: 376 MESLIGISVPVLSQIGNEIGASIPVFLITMVLYYILSR 413 SLIG+ VPVL + +I + V LI+ + Y +L R Sbjct: 436 --SLIGMYVPVLKSL-YDISWFVGV-LISFLFYIVLMR 469 >gi|6320902 purine-cytosine permease; Fcy21p [Saccharomyces cerevisiae] >gi|1723597|sp|P40039|YEP0_YEAST HYPOTHETICAL 58.1 KD PROTEIN IN PET117-CEM1 INTERGENIC REGION >gi|1321943|emb|CAA66032.1| (X97346) FCYY [Saccharomyces cerevisiae] >gi|1381128|gb|AAB64596.1| (U18813) Fcy21p: Purine-cytosine permease [Saccharomyces cerevisiae] Length = 528 Score = 77.3 bits (187), Expect = 3e-13 Identities = 94/424 (22%), Positives = 183/424 (42%), Gaps = 56/424 (13%) Query: 19 SIWFGADFGIAVIWAGAL--LTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTM 76 S+WF A+ + GAL + L+ +++ +II +LLG ++ ++ G E GL M Sbjct: 89 SMWFSANMVLPAYAIGALGPMVFDLNFGQSVFVIIFFNLLGLVSVAFFSVFGAELGLRQM 148 Query: 77 VLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPG----TYYAWVIVLG-- 130 +LSR +G + + SF+N++ IGW + + ++ L+++ PG + ++++G Sbjct: 149 ILSRYLVGNIAARIFSFINFIACIGWGIVNTVASSQVLNMVNPGHQCPLWAGCIVIIGAT 208 Query: 131 ILVTAW---TIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPGTGGLSLL 187 ++VT + I E+W W+ +V L+ + + K+ E + P T G ++L Sbjct: 209 VIVTFFGYGVIHAYEKWAWVPNFAVFLVIIARL----ARSKKFVLGEWTSGPTTAG-NVL 263 Query: 188 IALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSA----FCYFLG-ALSNVA 242 V W ADY+ + + + + + +VG A F LG A++ A Sbjct: 264 SFGSTVYGFAAGWTTYAADYTVYMPRKTN-KYKIFFSLVVGLATPLYFTMILGAAVAMAA 322 Query: 243 MG--------KEDPISLI--------AAYGLGIPAMLIVLISTLNTTFMDIY----SASI 282 +G E+ I + + +G G +++ +ST+ ++Y S Sbjct: 323 IGDPAWKTYYDENSIGGLTFAVLVPNSVHGFGQFCCVLLSLSTIANNVPNMYTIALSVQA 382 Query: 283 TWKNINPKANLKTQVLLVGTLGTLLALVFPVDKY-----EAFLLLIGGAFVPLAAIMITD 337 TW+ P A + + + L + P Y F+ IG AI ++ Sbjct: 383 TWE---PLAKVPRVIWTLLGNAAALGIAIPACYYFSTFMNYFMDSIGYYLAIYIAIACSE 439 Query: 338 YFLVKREYDAEKLLADES-----IRAPGIIAWVIG-FILYLSLTMESLIGISVPVLSQIG 391 +F+ +R + A + +S I G A ++G F + L + +G ++ G Sbjct: 440 HFIYRRSFSAYNVDDWDSWERLPIGIAGTAALIVGAFGVALGMCQTYWVGEISRLIGDYG 499 Query: 392 NEIG 395 +IG Sbjct: 500 GDIG 503 >pir||T28687 hypothetical protein - Streptomyces coelicolor >gi|3127838|emb|CAA18904.1| (AL023496) hypothetical protein [Streptomyces coelicolor A3(2)] Length = 522 Score = 76.9 bits (186), Expect = 4e-13 Identities = 112/467 (23%), Positives = 198/467 (41%), Gaps = 75/467 (16%) Query: 6 PVKEKIFDFWSNFSIWFGADFGIAVIW--AGALLTPYLSLKEALAIIILGHLLGNAVMSL 63 PV+ + + ++ ++W G A W A L+ + K+A+ I L +L+ A M L Sbjct: 49 PVEGRTWTTYNFSALWVGMAHNTAS-WTLASGLIAVGMDWKQAVFTIALANLIVLAPMLL 107 Query: 64 IAIEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIF----- 118 G + G+P V +R G +G+ LP+ + L GW I +G A+ + Sbjct: 108 TGHAGPKYGIPFPVFARASFGIRGANLPAVVRALVACGWFGIQTWIGGEAIYFLAGKLIG 167 Query: 119 -----PGTY--YAWVIVLGILVTAWTIVGPERWRWLEKL--------SVVLLGVLSVWLL 163 GT+ +AW + L + W + +R +E + VL+G V L Sbjct: 168 DGWTNAGTFGGHAWTMWLSFAI-FWALQVAIIYRGMETIRRFENWAAPFVLVGAF-VMLW 225 Query: 164 YVIFSKYSFSELWNKP---GTGGLSLLIALDLVIAMPLSWAP---TIADYSRFAKSRADA 217 ++ F L+++P G GG + ++ M W+ I D++R+ KS+ Sbjct: 226 WMADKAGGFGPLFDQPSRLGWGGDFWKLFWPSLMGMIGFWSTLSLNIPDFTRYGKSQRAQ 285 Query: 218 AWGTYLGHLVGSAFCYFLGAL----SNVAMGKE--DPISLIA----AYGLGIPAMLIVLI 267 G LG FL + S G+ DP+ L A GL + A++ VL+ Sbjct: 286 TRGQALGLPTTMTLFAFLSVMVTSGSQAVYGEPIWDPVQLAAKTDNVVGL-LFALVTVLV 344 Query: 268 STLNTTF-MDIYSASITWKNINP-KANLKTQVLLVGTLGTLLALVFPVDKYE-------A 318 +TL+ ++ S + + N+ P + + + L+ L L+FP Y Sbjct: 345 ATLSVNIAANLVSPAFDFSNVAPRRVSFRAGALITSVLA---VLIFPWKLYSDPQGYIFT 401 Query: 319 FLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADESIRA-----------PGIIAWVIG 367 +L L+GG +A I+I DY++++R A L D R ++A+V+G Sbjct: 402 WLGLVGGLLGTVAGILIADYWILRR---ARLHLVDLYRRGGRYWYEGGWNWRAVLAFVVG 458 Query: 368 FILYL-SLTMESLI-GISVPVLSQIGN-----EIGASIPVFLITMVL 407 +L + L+ G VP L + + + S+ ++LI M+L Sbjct: 459 GVLAVGGADFHPLVDGRPVPFLEPLADYGWAVGLATSLVLYLILMLL 505 >gb|AAG02126.1|AF146701_2 (AF146701) transport protein homolog [Arthrobacter aurescens] Length = 468 Score = 76.9 bits (186), Expect = 4e-13 Identities = 105/424 (24%), Positives = 181/424 (41%), Gaps = 51/424 (12%) Query: 30 VIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTMVLSRGPLGGKGS- 88 V+ ++ LS+ +A+ +I++ + L +M A G +G+PT +++R G +G+ Sbjct: 42 VVIGATIMVFGLSMWQAVVVILVANSL-MFLMGWFASIGAASGVPTSIITRALFGMRGNK 100 Query: 89 --------VLPSFLNYLQLIGWTAIMLIVGAR---ALDVIFPGTYYAWVIVLGILVTAWT 137 VL + + + L+ T L+V R A DV IV GI+V A T Sbjct: 101 VFGAGVVVVLSTLVTIVNLVIGTQGGLVVAERLGMAPDVA------TTAIVCGIIVLAST 154 Query: 138 IVGPERWRWLEKLSVVLLGVLS---VWLLYVIFSKYSFSELWNKPGTGG-LSLLIALDLV 193 + + + K S VL +++ V L + +F K + P + ++AL L Sbjct: 155 GLAIYGYNMMVKTSGVLTVIIAAAFVLLGFFVFQKVDLASFQPVPTENPVIGFIVALTLC 214 Query: 194 IAMPLSWAPTIADYSRFAKS---RADAAWGTYLGHLVGSAFCYFLGALSNVAMGKEDPIS 250 IAMPLSW + AD++R S R LG ++ +G L+ A +P++ Sbjct: 215 IAMPLSWG-SAADFARHIPSTTRRKPIVLAVGLGGMIPLVGLELVGVLAATATDMSEPVT 273 Query: 251 ---LIAAYGLGIPAMLIVLISTLNTTFMDIYSASITWKNINPKANLKTQVL---LVGTLG 304 + G +++++I ++ T M IY S+ + + V L +G Sbjct: 274 GLMNLVPDWFGTVLVVVIVIGSIMNTVMTIYGGSLAVQAAGVPVSRVVAVTGLGLTAAIG 333 Query: 305 TLLALVFP---VDKYEAFLLLIGGAFVPLAAIMITDYFLVKREYDAEKLLADES------ 355 T L F ++ + L +G +PL AI + D K YD L+D S Sbjct: 334 TAYVLFFADSFLNILQLGLTCLGSVAMPLTAIYLVDSVRRKGRYDG-VALSDPSQGGPYW 392 Query: 356 ----IRAPGIIAWVIGFIL-YLSLTMESLIGISVPVLSQIGNEIGASIPVFLITMVLYYI 410 R GI A + G ++ LSL S G P+ + +G + + + VL+ Sbjct: 393 HRGGFRLSGICALLGGSVVALLSLNGASYQG---PIAALLGGIDMSIVLGGTVAAVLFVA 449 Query: 411 LSRR 414 LSR+ Sbjct: 450 LSRQ 453 >pir||S50563 hypothetical protein YER060w - yeast (Saccharomyces cerevisiae) Length = 528 Score = 76.5 bits (185), Expect = 5e-13 Identities = 94/424 (22%), Positives = 183/424 (42%), Gaps = 56/424 (13%) Query: 19 SIWFGADFGIAVIWAGAL--LTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTM 76 S+WF A+ + GAL + L+ +++ +II +LLG ++ ++ G E GL M Sbjct: 89 SMWFSANMVLPAYAIGALGPMVFDLNFGQSVFVIIFFNLLGLVSVAFFSVFGAELGLRQM 148 Query: 77 VLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPG----TYYAWVIVLG-- 130 +LSR +G + + SF+N++ IGW + + ++ L+++ PG + ++++G Sbjct: 149 ILSRYLVGNIAARIFSFINFIACIGWGIVNTVASSQVLNMVNPGHQCPLWAGCIVIIGAT 208 Query: 131 ILVTAW---TIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPGTGGLSLL 187 ++VT + I E+W W+ +V L+ + + K+ E + P T G ++L Sbjct: 209 VIVTFFGYGVIHAYEKWAWVPNFAVFLVIIARL----ARSKKFVLGEWTSGPTTAG-NVL 263 Query: 188 IALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSA----FCYFLG-ALSNVA 242 V W ADY+ + + + + + +VG A F LG A++ A Sbjct: 264 SFGSTVYGFAAGWTTYAADYTVYMPRKTN-KYKIFFSLVVGLATPLYFTMILGAAVAMAA 322 Query: 243 MG--------KEDPISLI--------AAYGLGIPAMLIVLISTLNTTFMDIY----SASI 282 +G E+ I + + +G G +++ +ST+ ++Y S Sbjct: 323 IGDPAWKTYYDENSIGGLTFAVLVPNSVHGFGQFCCVLLSLSTIANNVPNMYTIALSVQA 382 Query: 283 TWKNINPKANLKTQVLLVGTLGTLLALVFPVDKY-----EAFLLLIGGAFVPLAAIMITD 337 TW+ P A + + + L + P Y F+ IG AI ++ Sbjct: 383 TWE---PLAKVPRVIWTLLGNAAALGIAIPACYYFSTFMNYFMDSIGYYLAIYIAIACSE 439 Query: 338 YFLVKREYDAEKLLADES-----IRAPGIIAWVIG-FILYLSLTMESLIGISVPVLSQIG 391 +F+ +R + A + +S I G A + G F + L + +G ++ + G Sbjct: 440 HFIYRRSFSAYNVDDWDSWERLPIGIAGTAALIAGAFGVALGMCQTYWVGEISRLIGEYG 499 Query: 392 NEIG 395 +IG Sbjct: 500 GDIG 503 >sp|Q01266|YHYC_PSESN HYPOTHETICAL PROTEIN IN HYUC 3'REGION (ORF 5) >gi|216834|dbj|BAA01380.1| (D10494) ORF5 unidentified protein [Pseudomonas sp.] Length = 245 Score = 76.1 bits (184), Expect = 7e-13 Identities = 56/242 (23%), Positives = 115/242 (47%), Gaps = 11/242 (4%) Query: 8 KEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIE 67 KE+ + F +W G + A L P LS + + ILG+L+ +++L+ Sbjct: 6 KERNMSSIAYFILWVGIAVQLVTPITAAQLYPALSPLQIIIACILGNLIVAILLTLLGDI 65 Query: 68 GQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFP-----GTY 122 G G+P V R G G+ +P + + + W +GA ALD I Sbjct: 66 GVRYGIPYAVYIRASFGYLGAHIPGIVRAVPAVFWFGFQTWMGAYALDAIMEMLTGYSNL 125 Query: 123 YAWVIVLGILVTAWTIVGPE---RWRWLEKLSVVLLGVLSVWLLYVIFSKY-SFSELWNK 178 +I+ G++ T +G E ++ WL S++++G+ + +Y++ + +FSE+++ Sbjct: 126 TLLIILFGVVQIINTAMGMEAITKFEWLASPSILIIGI--ILQVYIMKQHHLTFSEIFSH 183 Query: 179 PGTGGLSLLIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYFLGAL 238 G GG+S+ A+ +++ ++ A D++RF K++ ++ + GS + + G + Sbjct: 184 GGDGGVSMGYAVVVMMGTYITMALNAPDFTRFLKTKTGSSEPNWWKVNKGSFWAHTFGLI 243 Query: 239 SN 240 + Sbjct: 244 GS 245 >emb|CAC12338.1| (AL445066) purine-cytosine permease related protein [Thermoplasma acidophilum] Length = 480 Score = 76.1 bits (184), Expect = 7e-13 Identities = 88/366 (24%), Positives = 158/366 (43%), Gaps = 33/366 (9%) Query: 6 PVKEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIA 65 P +I W W A G LL P L L + L I + L+G + + + Sbjct: 34 PGTSRIMGPWKMTVFWSMASASALTPLIGYLLYP-LGLIDMLIAISIAFLIGFVPVGIFS 92 Query: 66 IEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPGTYYAW 125 G+ +P M++SR LG S + S + +GW + I G L + + W Sbjct: 93 EMGRTIPVPAMIISRKTLGYASSSVMSLIFTFVNLGWFGLNDITGGLILASVTSSSPIIW 152 Query: 126 VIVLGILVTAWTIVGPER----WRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPGT 181 + + I+ + G + +R+ L V G+L+ +LL+ ++ ++ L P T Sbjct: 153 ISFMAIVQIMLVLFGAKYLEKFYRYTAILLVFSYGILT-YLLFRVYRPDMYAVL--HPST 209 Query: 182 GGLSLLIALDLVIAMP-LSWAPTIADYSRFAKSR-----ADAAWGTYLGHLVGSAF-CYF 234 ++ A+ LV+A L+WA ++ SRFA+ R A G ++ +G Y Sbjct: 210 -AVNWGSAIGLVLAFSILAWAYKVSTISRFARKREAGEPALERSGFFMAPSIGIIVPVYV 268 Query: 235 LGALSNVAMGKEDPISLIAA--YGLG-------IPAMLIVLISTLNTTFMDIYSASITWK 285 +G+L ++ + +L A GLG I A + ++ ++T M++Y A+ Sbjct: 269 MGSLGLISEAAAENWNLAAVRFSGLGSIGGAVAIIASIGASLAIIHTNSMNLYPATADLL 328 Query: 286 N-----INPKANLKTQVL---LVGTLGTLLALVFPVDKYEAFLLLIGGAFVPLAAIMITD 337 + N + Q + ++GTLG +LA ++ FL L G P ++I D Sbjct: 329 SAIEGLFNKRLRKFAQPISTAILGTLGAVLAYAGILNYASGFLNLSGSIIFPFTFVLIAD 388 Query: 338 YFLVKR 343 +F++ R Sbjct: 389 WFMMNR 394 >pir||T48383 uracil transporter-like protein - Arabidopsis thaliana >gi|7378642|emb|CAB83318.1| (AL162751) uracil transporter-like protein [Arabidopsis thaliana] Length = 599 Score = 75.7 bits (183), Expect = 9e-13 Identities = 89/388 (22%), Positives = 166/388 (41%), Gaps = 51/388 (13%) Query: 2 EEIKPV--KEKIFDFWSNFSIWFGADFGIAVIW-AGALLTPYLSLKEALAIIILGHLLGN 58 +++KP ++ F + S+W G G+ + AG+L+ ++ + +A ++ +L+ Sbjct: 120 DDLKPTTPSQRTFSWLDMSSLWIGLVVGVPTYYLAGSLVDLGMAWWQGIATVVTANLILL 179 Query: 59 AVMSLIAIEGQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIF 118 + L A G G+ VL+R G +G+ +P+ L L GW I +G A+ ++ Sbjct: 180 VPLVLTAQPGTLYGISFPVLARSSFGIRGAHIPTLLRALVGCGWYGIETWIGGEAIFLLL 239 Query: 119 PGTYYAWVIVLGILVTAWTIVGPERWR-----WLEKLSVVLLGV-----LSVWLLYVIFS 168 PG + + W P + WL +L +V G+ L + ++ S Sbjct: 240 PGHIKKSALSHTL---PWLGTSPLEFSCFIVFWLAQLCIVWRGMDGIRKLEKYSAPILIS 296 Query: 169 KYSFSELWNKPGTGGLSLLIALDLVIAMPLSW-----------------APTIADYSRFA 211 S W+ GG +++L + W A I D+SRFA Sbjct: 297 LTSCLLAWSYLKAGGFGHMLSLSSKLTSAQFWTLFFPSLTANISFWATLALNIPDFSRFA 356 Query: 212 KSRADAAWGTYLGHLVGSAFCYFLG----ALSNVAMGK--EDPISLIAAYGLGIPAMLIV 265 KS+ D G +G V F+G + +++ G+ +PI L+ G G+ L+ Sbjct: 357 KSQTDQIIG-QVGLPVFMGLFTFVGVAVTSSTSIIFGRVISNPIELLGQIG-GLATTLLA 414 Query: 266 LI----STLNTTF-MDIYSASITWKNINPK-ANLKTQVLLVGTLGTLLALVFPVDKYEAF 319 ++ +TL T ++ + + N+NPK L LG + + E+F Sbjct: 415 IVGISLATLTTNIAANVVAPANALVNLNPKFFTFGRGAFLTAVLGIVFQPWRLLKSSESF 474 Query: 320 LL--LIGGAFV--PLAAIMITDYFLVKR 343 + LIG + + P+ I++ DY+L+K+ Sbjct: 475 VYTWLIGYSALLGPIGGIILVDYYLIKK 502 >gb|AAA25848.1| (M72717) ORF 5 [Pseudomonas sp.] Length = 233 Score = 75.3 bits (182), Expect = 1e-12 Identities = 53/220 (24%), Positives = 107/220 (48%), Gaps = 11/220 (5%) Query: 8 KEKIFDFWSNFSIWFGADFGIAVIWAGALLTPYLSLKEALAIIILGHLLGNAVMSLIAIE 67 KE+ + F +W G + A L P LS + + ILG+L+ +++L+ Sbjct: 6 KERNMSSIAYFILWVGIAVQLVTPITAAQLYPALSPLQIIIACILGNLIVAILLTLLGDI 65 Query: 68 GQETGLPTMVLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFP-----GTY 122 G G+P V R G G+ +P + + + W +GA ALD I Sbjct: 66 GVRYGIPYAVYIRASFGYLGAHIPGIVRAVPAVFWFGFQTWMGAYALDAIMEMLTGYSNL 125 Query: 123 YAWVIVLGILVTAWTIVGPE---RWRWLEKLSVVLLGVLSVWLLYVIFSKY-SFSELWNK 178 +I+ G++ T +G E ++ WL S++++G+ + +Y++ + +FSE+++ Sbjct: 126 TLLIILFGVVQIINTAMGMEAITKFEWLASPSILIIGI--ILQVYIMKQHHLTFSEIFSH 183 Query: 179 PGTGGLSLLIALDLVIAMPLSWAPTIADYSRFAKSRADAA 218 G GG+S+ A+ +++ ++ A D++RF K++ ++ Sbjct: 184 GGDGGVSMGYAVVVMMGTYITMALNAPDFTRFLKTKTGSS 223 >sp|P75712|ALLP_ECOLI PUTATIVE ALLANTOIN PERMEASE (ALLANTOIN TRANSPORT PROTEIN) >gi|1773191|gb|AAB40263.1| (U82664) similar to Pseudomonas sp. ORF5 [Escherichia coli] >gi|2735237|gb|AAB93852.1| (U89279) GlxB2 [Escherichia coli] Length = 484 Score = 72.2 bits (174), Expect = 1e-11 Identities = 92/398 (23%), Positives = 169/398 (42%), Gaps = 46/398 (11%) Query: 5 KPVKEKIFDFWSNFSIWFGADFGIA-VIWAGALLTPYLSLKEALAIIILGHLLGNAVMSL 63 K ++ + ++ F++W G+ + + G LS + IIL AVM L Sbjct: 20 KTQSQRTWKTFNYFTLWMGSVHNVPNYVMVGGFFILGLSTFSIMLAIILSAFFIAAVMVL 79 Query: 64 IAIEGQETGLPTMVLSRGPLGGKGSVLPSFL-NYLQLIGWTAIMLIVGARA----LDVIF 118 G + G+P ++ R G +G++ P L + I W + G+ A + I+ Sbjct: 80 NGAAGSKYGVPFAMILRASYGVRGALFPGLLRGGIAAIMWFGLQCYAGSLACLILIGKIW 139 Query: 119 PG--TYYAWVIVLGI----LVT---AWTI---VGPERWRWLEKLSVVL-------LGVLS 159 PG T +LG+ L+T W + +G + L K + +L G ++ Sbjct: 140 PGFLTLGGDFTLLGLSLPGLITFLIFWLVNVGIGFGGGKVLNKFTAILNPCIYIVFGGMA 199 Query: 160 VWLLYVIFSKYSFSEL---WNKPGTGGLSLLIALDLVIAMPLSWAPTIADYSRFAKSRAD 216 +W + ++ F + K GG L+ ++ V+A+ + A + +D+++ A S + Sbjct: 200 IWAISLVGIGPIFDYIPSGIQKAENGGFLFLVVINAVVAVWAAPAVSASDFTQNAHSFRE 259 Query: 217 AAWGTYLGHLVG------SAFCYFLGALSNVAMGKEDPISLIAAYG---LGIPAMLIVLI 267 A G LG +V + C GA + + + ++ + A+L++L+ Sbjct: 260 QALGQTLGLVVAYILFAVAGVCIIAGASIHYGADTWNVLDIVQRWDSLFASFFAVLVILM 319 Query: 268 STLNTTFM-DIYSASITWKNINP-KANLKTQVLLVGTLGTLLA---LVFPVDKYEAFLLL 322 +T++T +I A I P K K VL+ + L+ L+ D FL + Sbjct: 320 TTISTNATGNIIPAGYQIAAIAPTKLTYKNGVLIASIISLLICPWKLMENQDSIYLFLDI 379 Query: 323 IGGAFVPLAAIMITDYFLVKREYDAEKLLADESIRAPG 360 IGG P+ +M+ YF+V R ++ DE APG Sbjct: 380 IGGMLGPVIGVMMAHYFVVMR----GQINLDELYTAPG 413 >emb|CAA36040.1| (X51751) cytosine-purine permease (AA 1-533) [Saccharomyces cerevisiae] Length = 533 Score = 71.8 bits (173), Expect = 1e-11 Identities = 95/423 (22%), Positives = 182/423 (42%), Gaps = 52/423 (12%) Query: 19 SIWFGADFGIAVIWAGAL--LTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTM 76 S+WF A+ IA GAL + L+ +++ +II +++G ++ ++ G E GL M Sbjct: 92 SMWFSANMVIASYALGALGPMVFGLNFGQSVLVIIFFNIMGLIFVAFFSVFGAELGLRQM 151 Query: 77 VLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPGTYYA---W---VIVLG 130 +LSR +G + + S +N + +GW + V A+ L+++ G+ + W +I++G Sbjct: 152 ILSRYLVGNVTARIFSLINVIACVGWGIVNTSVSAQLLNMMNEGSGHVCPIWAGCLIIIG 211 Query: 131 --ILVTAW---TIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPGTGGLS 185 +LVT + I E+W W+ +V L+ + + K+ E W GT S Sbjct: 212 GTVLVTFFGYSVIHAYEKWSWVPNFAVFLVIIAQL----SRSGKFKGGE-WVGGGTTAGS 266 Query: 186 LLIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYF----LGALSNV 241 +L + W ADY+ + ++ + + + G AF F LGA S + Sbjct: 267 VLSFGSSIFGFAAGWTTYAADYTVY-MPKSTNKYKIFFSLVAGLAFPLFFTMILGAASAM 325 Query: 242 ---------------AMGKEDPISLI--AAYGLGIPAMLIVLISTLNTTFMDIYSASITW 284 AMG L+ + G G +++ +ST+ ++Y+ +++ Sbjct: 326 AALNDPTWKAYYDKNAMGGVIYAILVPNSLNGFGQFCCVLLALSTIANNIPNMYTVALSA 385 Query: 285 KNI-NPKANLKTQVLLVGTLGTLLALVFPVDKY-----EAFLLLIGGAFVPLAAIMITDY 338 + + P A + V + L + P Y E F+ IG AI +++ Sbjct: 386 QALWAPLAKIPRVVWTMAGNAATLGISIPATYYFDGFMENFMDSIGYYLAIYIAISCSEH 445 Query: 339 FLVKREYDAEKLLADES-----IRAPGIIAWVIG-FILYLSLTMESLIGISVPVLSQIGN 392 F +R + A + ++ I G A ++G F + L + +G ++ + G Sbjct: 446 FFYRRSFSAYNIDDWDNWEHLPIGIAGTAALIVGAFGVALGMCQTYWVGEIGRLIGKYGG 505 Query: 393 EIG 395 +IG Sbjct: 506 DIG 508 >gi|6320897 purine-cytosine permease; Fcy2p [Saccharomyces cerevisiae] >gi|729467|sp|P17064|FCY2_YEAST PURINE-CYTOSINE PERMEASE (PCP) (CYTOSINE/PURINE TRANSPORT PROTEIN) >gi|1070658|pir||GRBYCP cytosine/purine transport protein - yeast (Saccharomyces cerevisiae) >gi|603292|gb|AAB64592.1| (U18813) Fcy2p: purine-cytosine permease [Saccharomyces cerevisiae] Length = 533 Score = 70.2 bits (169), Expect = 4e-11 Identities = 94/423 (22%), Positives = 181/423 (42%), Gaps = 52/423 (12%) Query: 19 SIWFGADFGIAVIWAGAL--LTPYLSLKEALAIIILGHLLGNAVMSLIAIEGQETGLPTM 76 S+WF A+ IA GAL + L+ +++ +II +++G ++ ++ G E GL M Sbjct: 92 SMWFSANMVIASYALGALGPMVFGLNFGQSVLVIIFFNIMGLIFVAFFSVFGAELGLRQM 151 Query: 77 VLSRGPLGGKGSVLPSFLNYLQLIGWTAIMLIVGARALDVIFPGTYYA---W---VIVLG 130 +LSR +G + + S +N + +GW + V A+ L+++ G+ + W +I++G Sbjct: 152 ILSRYLVGNVTARIFSLINVIACVGWGIVNTSVSAQLLNMVNEGSGHVCPIWAGCLIIIG 211 Query: 131 --ILVTAW---TIVGPERWRWLEKLSVVLLGVLSVWLLYVIFSKYSFSELWNKPGTGGLS 185 +LVT + I E+W W+ +V L+ + + K+ E W T S Sbjct: 212 GTVLVTFFGYSVIHAYEKWSWVPNFAVFLVIIAQL----SRSGKFKGGE-WVGGATTAGS 266 Query: 186 LLIALDLVIAMPLSWAPTIADYSRFAKSRADAAWGTYLGHLVGSAFCYF----LGALSNV 241 +L + W ADY+ + ++ + + + G AF F LGA S + Sbjct: 267 VLSFGSSIFGFAAGWTTYAADYTVY-MPKSTNKYKIFFSLVAGLAFPLFFTMILGAASAM 325 Query: 242 ---------------AMGKEDPISLI--AAYGLGIPAMLIVLISTLNTTFMDIYSASITW 284 AMG L+ + G G +++ +ST+ ++Y+ +++ Sbjct: 326 AALNDPTWKAYYDKNAMGGVIYAILVPNSLNGFGQFCCVLLALSTIANNIPNMYTVALSA 385 Query: 285 KNI-NPKANLKTQVLLVGTLGTLLALVFPVDKY-----EAFLLLIGGAFVPLAAIMITDY 338 + + P A + V + L + P Y E F+ IG AI +++ Sbjct: 386 QALWAPLAKIPRVVWTMAGNAATLGISIPATYYFDGFMENFMDSIGYYLAIYIAISCSEH 445 Query: 339 FLVKREYDAEKLLADES-----IRAPGIIAWVIG-FILYLSLTMESLIGISVPVLSQIGN 392 F +R + A + ++ I G A ++G F + L + +G ++ + G Sbjct: 446 FFYRRSFSAYNIDDWDNWEHLPIGIAGTAALIVGAFGVALGMCQTYWVGEIGRLIGKYGG 505 Query: 393 EIG 395 +IG Sbjct: 506 DIG 508 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.326 0.143 0.438 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 155241751 Number of Sequences: 2977 Number of extensions: 6467489 Number of successful extensions: 22072 Number of sequences better than 1.0e-10: 28 Number of HSP's better than 0.0 without gapping: 4 Number of HSP's successfully gapped in prelim test: 24 Number of HSP's that attempted gapping in prelim test: 21994 Number of HSP's gapped (non-prelim): 31 length of query: 414 length of database: 189,106,746 effective HSP length: 52 effective length of query: 362 effective length of database: 157,985,422 effective search space: 57190722764 effective search space used: 57190722764 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 40 (21.6 bits) S2: 166 (69.1 bits)