BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1674 (lysC-like1) DE:aspartate kinase (lysC) related
(368 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||B75081 aspartate kinase (lysc) related PAB1674 - Pyrococcus... 735 0.0
pir||C71103 probable aspartokinase - Pyrococcus horikoshii >gi|3... 443 e-123
pir||A75081 aspartate kinase related (lysc) PAB1675 - Pyrococcus... 250 2e-65
pir||F71136 hypothetical protein PH0858 - Pyrococcus horikoshii ... 210 3e-53
sp|Q57991|AK_METJA PROBABLE ASPARTOKINASE (ASPARTATE KINASE) >gi... 123 4e-27
gi|11498307 aspartate kinase (lysC) [Archaeoglobus fulgidus] >gi... 115 9e-25
sp|P57290|AKH_BUCAI BIFUNCTIONAL ASPARTOKINASE/HOMOSERINE DEHYDR... 109 5e-23
pir||C46665 aspartate kinase (EC 2.7.2.4) I - Bacillus subtilis ... 106 4e-22
sp|Q04795|AK1_BACSU ASPARTOKINASE 1 (ASPARTOKINASE I) (ASPARTATE... 106 4e-22
pir||E81405 aspartate kinase (EC 2.7.2.4) alpha and beta chains ... 105 1e-21
pir||H72364 aspartokinase II - Thermotoga maritima (strain MSB8)... 104 2e-21
sp|P08660|AK3_ECOLI LYSINE-SENSITIVE ASPARTOKINASE III (ASPARTAT... 103 3e-21
gb|AAA24095.1| (M11812) aspartokinase III [Escherichia coli] 103 4e-21
sp|O25827|AK_HELPY ASPARTOKINASE (ASPARTATE KINASE) >gi|7434553|... 102 8e-21
dbj|BAB06119.1| (AP001515) aspartokinase I (alpha and beta subun... 100 4e-20
sp|Q9ZJZ7|AK_HELPJ ASPARTOKINASE (ASPARTATE KINASE) >gi|7434552|... 98 2e-19
sp|P44505|AKH_HAEIN BIFUNCTIONAL ASPARTOKINASE/HOMOSERINE DEHYDR... 97 3e-19
dbj|BAA38474.1| (D10385) aspartokinase I-homoserine dehydrogenas... 97 3e-19
sp|P27725|AK1H_SERMA BIFUNCTIONAL ASPARTOKINASE/HOMOSERINE DEHYD... 97 4e-19
dbj|BAA38477.1| (D10386) aspartokinase I-homoserine dehydrogenas... 97 4e-19
dbj|BAA38480.1| (D10387) aspartokinase I-homoserine dehydrogenas... 97 4e-19
pir||DEECK thrA bifunctional enzyme - Escherichia coli >gi|53724... 96 8e-19
sp|P00561|AK1H_ECOLI BIFUNCTIONAL ASPARTOKINASE/HOMOSERINE DEHYD... 95 1e-18
sp|P41403|AK_MYCSM ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: A... 94 2e-18
pir||E72715 probable aspartate kinase APE1140 - Aeropyrum pernix... 94 2e-18
emb|CAA23660.1| (V00361) thrA gene [EC 2.7.2.4 and EC 1.1.1.3] [... 94 3e-18
sp|P26512|AK_CORGL ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: A... 93 4e-18
gb|AAD49567.1|AF134837_1 (AF134837) aspartokinase subunit A [Amy... 91 2e-17
sp|P41398|AK_CORFL ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: A... 91 2e-17
sp|P53553|AK2_BACST ASPARTOKINASE 2 (ASPARTOKINASE II) (ASPARTAT... 89 6e-17
sp|Q59229|AK2_BACSP ASPARTOKINASE 2 (ASPARTOKINASE II) (ASPARTAT... 89 8e-17
sp|Q9ZCI7|AK_RICPR ASPARTOKINASE (ASPARTATE KINASE) >gi|7434558|... 89 8e-17
pir||H82086 aspartokinase I/homoserine dehydrogenase, threonine-... 89 1e-16
pir||T35383 probable aspartokinase - Streptomyces coelicolor >gi... 89 1e-16
sp|O67221|AK_AQUAE ASPARTOKINASE (ASPARTATE KINASE) >gi|7434554|... 89 1e-16
gb|AAD41796.1| (AF135862) precursor monofunctional aspartokinase... 89 1e-16
emb|CAA99580.1| (Z75208) aspartokinase II alpha subunit [Bacillu... 88 1e-16
pir||F82328 aspartokinase III, lysine-sensitive VC0391 [imported... 88 2e-16
pir||B69207 aspartokinase II alpha subunit - Methanobacterium th... 87 2e-16
pir||T48575 aspartate kinase - Arabidopsis thaliana >gi|7529283|... 87 2e-16
dbj|BAB08285.1| (AB007650) lysine-sensitive aspartate kinase [Ar... 87 2e-16
pir||H81865 aspartate kinase (EC 2.7.2.4) NMA1701 [imported] - N... 87 2e-16
sp|P77991|AK_THEFL ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: A... 87 2e-16
emb|CAA67376.1| (X98873) aspartate kinase [Arabidopsis thaliana] 87 3e-16
sp|P08495|AK2_BACSU ASPARTOKINASE 2 (ASPARTOKINASE II) (ASPARTAT... 87 3e-16
pir||A82311 aspartokinase, alpha and beta chains VC0547 [importe... 86 5e-16
pir||F81076 aspartokinase, alpha and beta chains NMB1498 [import... 86 5e-16
sp|P97151|AK_THETH ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: A... 86 7e-16
gb|AAB49995.1| (U90239) aspartokinase [Mycobacterium tuberculosis] 85 1e-15
sp|P97048|AK_MYCTU ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: A... 85 1e-15
gb|AAK41163.1| Aspartokinase (akH) [Sulfolobus solfataricus] 85 2e-15
dbj|BAB06815.1| (AP001517) aspartokinase II alpha and beta subun... 85 2e-15
pir||G72245 aspartokinase II - Thermotoga maritima (strain MSB8)... 84 2e-15
gb|AAF03452.1|AC010797_28 (AC010797) putative aspartate kinase [... 84 3e-15
emb|CAC06395.1| (Y16255) aspartate kinase [Arabidopsis thaliana] 83 4e-15
gb|AAB63104.1| (U62020) lysine-sensitive aspartate kinase [Arabi... 83 6e-15
pir||D81681 aspartokinase III TC0641 [imported] - Chlamydia muri... 82 8e-15
emb|CAC11508.1| (AL445064) aspartate kinase related protein [The... 81 2e-14
pir||F75405 aspartate kinase - Deinococcus radiodurans (strain R... 80 3e-14
emb|CAB57346.1| (Y15939) aspartokinase [Dichelobacter nodosus] 80 5e-14
pir||C83531 aspartate kinase alpha and beta chain PA0904 [import... 77 4e-13
pir||T39822 aspartate kinase - fission yeast (Schizosaccharomyce... 76 5e-13
pir||S76764 hypothetical protein - Synechocystis sp. (strain PCC... 75 1e-12
dbj|BAA95630.1| (AB042521) aspartate kinase [Oryza sativa] 71 2e-11
pir||T04752 aspartate kinase (EC 2.7.2.4) / homoserine dehydroge... 69 6e-11
>pir||B75081 aspartate kinase (lysc) related PAB1674 - Pyrococcus abyssi
(strain Orsay) >gi|5458463|emb|CAB49951.1| (AJ248286)
aspartate kinase (lysC) related [Pyrococcus abyssi]
Length = 368
Score = 735 bits (1878), Expect = 0.0
Identities = 368/368 (100%), Positives = 368/368 (100%)
Query: 1 MRKMIVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
MRKMIVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA
Sbjct: 1 MRKMIVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
Query: 61 IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE
Sbjct: 61 IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
Query: 121 GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMDGYRVTLG 180
GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMDGYRVTLG
Sbjct: 121 GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMDGYRVTLG 180
Query: 181 RGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAKHGMK 240
RGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAKHGMK
Sbjct: 181 RGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAKHGMK 240
Query: 241 AIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDGLLLINVEEELEYRV 300
AIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDGLLLINVEEELEYRV
Sbjct: 241 AIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDGLLLINVEEELEYRV 300
Query: 301 IDEGPFWKLYDVPGNEGIRIIRELHKAIFGNVLSMLQEPGKHIRINRHKVGKSFEHMTFN 360
IDEGPFWKLYDVPGNEGIRIIRELHKAIFGNVLSMLQEPGKHIRINRHKVGKSFEHMTFN
Sbjct: 301 IDEGPFWKLYDVPGNEGIRIIRELHKAIFGNVLSMLQEPGKHIRINRHKVGKSFEHMTFN 360
Query: 361 QSFSRKFY 368
QSFSRKFY
Sbjct: 361 QSFSRKFY 368
>pir||C71103 probable aspartokinase - Pyrococcus horikoshii
>gi|3257502|dbj|BAA30185.1| (AP000004) 346aa long
hypothetical aspartokinase [Pyrococcus horikoshii]
Length = 346
Score = 443 bits (1126), Expect = e-123
Identities = 205/327 (62%), Positives = 276/327 (83%), Gaps = 1/327 (0%)
Query: 3 KMIVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYAIK 62
KMIV+KFGGSS++++F AVSL K++ EEK+V VVVSALKGITD+L KY TFDS+YA++
Sbjct: 6 KMIVIKFGGSSLRSEFKSAVSLIKALSEEKDVVVVVSALKGITDLLEKYTDTFDSRYAVE 65
Query: 63 IADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVEGQ 122
++ +Y++F + G+D + LSP++++LFNPP LP AL DYILSIGELLSA + AE G
Sbjct: 66 VSKTYLEFGKRMGIDTSSLSPYLKQLFNPPDLPPQALRDYILSIGELLSAAMIAEKANGA 125
Query: 123 VIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMDGYRVTLGRG 182
VI+PW+LF A+G FG+GFID+KKSK+N K++ E ++SGKIPI+PGF+ ++GYRVTLGRG
Sbjct: 126 VIFPWDLFVAHGSFGNGFIDIKKSKRNVKLVKEALESGKIPIIPGFIANLNGYRVTLGRG 185
Query: 183 GSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAKHGMKAI 242
GSDYSAVALGV+LNSELVAIMS+VEGIFTADPK++P + LIPY+SY+E LIA+K+GM+AI
Sbjct: 186 GSDYSAVALGVLLNSELVAIMSDVEGIFTADPKMIPYSLLIPYMSYDEILIASKYGMEAI 245
Query: 243 QWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDG-LLLINVEEELEYRVI 301
QWKAA+LAKE + L+LFGR ++WRMGTV+SN +S MPL++Y G LL++N++ E+ Y V+
Sbjct: 246 QWKAAKLAKEYEALILFGRASDWRMGTVVSNSSSHMPLLSYDQGKLLVMNMDSEIPYEVV 305
Query: 302 DEGPFWKLYDVPGNEGIRIIRELHKAI 328
+EG FW++Y VP + I+II+ELH+ I
Sbjct: 306 EEGEFWRVYRVPKRDSIKIIKELHRKI 332
>pir||A75081 aspartate kinase related (lysc) PAB1675 - Pyrococcus abyssi
(strain Orsay) >gi|5458462|emb|CAB49950.1| (AJ248286)
aspartate kinase related (lysC) [Pyrococcus abyssi]
Length = 352
Score = 250 bits (631), Expect = 2e-65
Identities = 136/287 (47%), Positives = 192/287 (66%), Gaps = 13/287 (4%)
Query: 3 KMIVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYAIK 62
K++V+KFGGSSV+ F EA+ L K + E + VVVSALKG+TD LI++A D +
Sbjct: 4 KLLVVKFGGSSVRYAFEEALELVKYLSERIPIVVVVSALKGVTDELIRFANG-DKGALPR 62
Query: 63 IADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE-- 120
I + +F +G++ I +++ P +AL D I+S+GE +SA IFAE +E
Sbjct: 63 IERIHEEFLNYHGLNTKISISFRKDM------PPEALRDEIISLGERISAKIFAEGLELL 116
Query: 121 ---GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMDGYRV 177
+V+ P E A G+FGD +I++++SK+ A + +I SG IP++PGF G ++G+RV
Sbjct: 117 GIKSKVVDPLEFLIAKGEFGDAYINIQESKRRAGKLIRLIKSGVIPVIPGFYGNLNGFRV 176
Query: 178 TLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAKH 237
T GRGGSDYSA AL IL+S V IMS+VEGIFTADPKLVPSARLIPYLSYEE +AAK
Sbjct: 177 TFGRGGSDYSATALARILDSRCVLIMSDVEGIFTADPKLVPSARLIPYLSYEEIKVAAKL 236
Query: 238 GMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYK 284
GMKA+ WKA + I ++FG+T +W+ GT++ N S P++ ++
Sbjct: 237 GMKALHWKAVD-PVVGDIPIIFGKTKDWKFGTIVLNARSNFPIIVHR 282
>pir||F71136 hypothetical protein PH0858 - Pyrococcus horikoshii
>gi|3257269|dbj|BAA29952.1| (AP000003) 359aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 359
Score = 210 bits (528), Expect = 3e-53
Identities = 119/345 (34%), Positives = 204/345 (58%), Gaps = 16/345 (4%)
Query: 1 MRKMIVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
+ K +V+KFGG+SV+ F EA+ L + E ++ VVVSAL G+TD L++ AK D
Sbjct: 2 VEKPVVIKFGGTSVRYAFEEALELVAKLHENMKIIVVVSALAGVTDCLLRLAKG-DKSAL 60
Query: 61 IKIADSYVKFARTNGVDPNILSPHIQELFNPPS-LPKD-ALTDYILSIGELLSAVIFAEV 118
++I + + + ++ V L +++ N S P + A D I S GE SA +F+E
Sbjct: 61 LEIDEIHEELSQELNVQLEHLIHQLKKTINSKSSFPSEKAFIDEIASFGERFSAKLFSEG 120
Query: 119 VE-----GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMD 173
++ + + ++ G+FG+ ++ KKS + ++Y ++ G +P+V G+ G ++
Sbjct: 121 LKILGITARPVDSKDVLFVKGEFGNAEVEFKKSAQGVDVLYRMLRRGIVPVVTGYYGNLN 180
Query: 174 GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALI 233
G+R T GRGGSDYSA ++ ++N++ V IMS+VEGI+TADPKLVP ARLI Y+SY+EA
Sbjct: 181 GFRATFGRGGSDYSATSIASLVNAKAVLIMSDVEGIYTADPKLVPPARLIHYISYKEAKT 240
Query: 234 AAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYK-------DG 286
AAK GMK + +A + E KI ++ G+T + + GT+IS+ + +P++T+K
Sbjct: 241 AAKLGMKVLHPRAID-PVEGKIPVILGKTRDLKFGTLISHESQGIPIVTHKLLENHAEIS 299
Query: 287 LLLINVEEELEYRVIDEGPFWKLYDVPGNEGIRIIRELHKAIFGN 331
++ + L Y V +EG + ++ + ++R++H+ + N
Sbjct: 300 VVSVKTNIPLPYEVYEEGDLYFKIKTSKDQFLEVLRDVHRRVVEN 344
>sp|Q57991|AK_METJA PROBABLE ASPARTOKINASE (ASPARTATE KINASE) >gi|2127773|pir||C64371
aspartate kinase (EC 2.7.2.4) I - Methanococcus
jannaschii >gi|1591278|gb|AAB98565.1| (U67506) aspartate
kinase (lysC) [Methanococcus jannaschii]
Length = 473
Score = 123 bits (305), Expect = 4e-27
Identities = 102/303 (33%), Positives = 154/303 (50%), Gaps = 41/303 (13%)
Query: 6 VLKFGGSSVKNDF---HEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAK-TFDSKYAI 61
V+KFGG+SV + H A +TK E+ +V VVVSA+ +T+ L++ ++ D +
Sbjct: 4 VMKFGGTSVGSGERIRHVAKIVTKRKKEDDDVVVVVSAMSEVTNALVEISQQALDVRDIA 63
Query: 62 KIADSYVKFARTN---GVDPNILSPHIQE--------------------LFNPPSLPKDA 98
K+ D ++KF R ++ I S I+E + PK
Sbjct: 64 KVGD-FIKFIREKHYKAIEEAIKSEEIKEEVKKIIDSRIEELEKVLIGVAYLGELTPKSR 122
Query: 99 LTDYILSIGELLSAVIFAEVVE--GQVIYPWELFSAY----GKFGDGFIDLKKSKKNAKI 152
DYILS GE LS+ I + + G+ E A FG + + K+
Sbjct: 123 --DYILSFGERLSSPILSGAIRDLGEKSIALEGGEAGIITDNNFGSARVKRLEVKER--- 177
Query: 153 IYEVIDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFT 211
+ ++ G IP+V GF+G + GY TLGRGGSDYSA +G L+++++ I ++V G++T
Sbjct: 178 LLPLLKEGIIPVVTGFIGTTEEGYITTLGRGGSDYSAALIGYGLDADIIEIWTDVSGVYT 237
Query: 212 ADPKLVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRT-NNWRMGTV 270
DP+LVP+AR IP LSY EA+ A G K + + E A EK I +L T GT+
Sbjct: 238 TDPRLVPTARRIPKLSYIEAMELAYFGAKVLHPRTIEPAMEKGIPILVKNTFEPESEGTL 297
Query: 271 ISN 273
I+N
Sbjct: 298 ITN 300
>gi|11498307 aspartate kinase (lysC) [Archaeoglobus fulgidus]
>gi|7448935|pir||D69337 aspartate kinase (lysC) homolog
- Archaeoglobus fulgidus >gi|2649914|gb|AAB90539.1|
(AE001056) aspartate kinase (lysC) [Archaeoglobus
fulgidus]
Length = 462
Score = 115 bits (285), Expect = 9e-25
Identities = 105/310 (33%), Positives = 149/310 (47%), Gaps = 46/310 (14%)
Query: 5 IVLKFGGSSVKN--DFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA-- 60
IV+KFGG SVK+ + + +L K E EV VVVSA++G+TD L+K A S+ +
Sbjct: 3 IVMKFGGVSVKDGENIYHCANLVKKFSEGNEVVVVVSAMQGVTDALLKAAHRCCSEPSAG 62
Query: 61 ---IKIADSY------VKFARTNGVDPNILSPHIQELFNPPSLPKDAL------------ 99
+ IAD +++A N + ++ L + L K L
Sbjct: 63 FIKMFIADMMKRHYEAIEYAVRNDEIKAKVIAAVERLLD--ELEKVLLGISYLGELTRRS 120
Query: 100 TDYILSIGELLSAVIFAEVVEGQVIYPWELFSAYGKFGDGFIDLKKSKKNAKI---IYEV 156
DYI+S GE LSA IF+ + + L GD I ++ AK +Y
Sbjct: 121 EDYIVSFGERLSAPIFSAALLSLGVDSVALTG-----GDAGIITDRNFGRAKPLPGVYTT 175
Query: 157 IDS---------GKIPIVPGFVGGM-DGYRVTLGRGGSDYSAVALGVILNSELVAIMSNV 206
I + IP+V GF+G DG TLGRGGSDY+A L L+++ V + V
Sbjct: 176 IRNRLEPLLTIKKTIPVVTGFIGATDDGSITTLGRGGSDYTATILAAALDADEVWLWKEV 235
Query: 207 EGIFTADPKLVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRT-NNW 265
+GI T DPK VP+AR+IP +SY+EA+ + G K + +A E K I + T N
Sbjct: 236 DGIMTCDPKYVPNARVIPEISYQEAMELSHFGAKILHPRALEPVMRKNIPVRIKNTFNPD 295
Query: 266 RMGTVISNRT 275
GTVI T
Sbjct: 296 APGTVIGPTT 305
>sp|P57290|AKH_BUCAI BIFUNCTIONAL ASPARTOKINASE/HOMOSERINE DEHYDROGENASE (AK-HD)
[INCLUDES: ASPARTOKINASE ; HOMOSERINE DEHYDROGENASE ]
>gi|10038876|dbj|BAB12911.1| (AP001118) aspartokinase I
/ homoserine dehydrogenase I [Buchnera sp. APS]
Length = 816
Score = 109 bits (270), Expect = 5e-23
Identities = 94/324 (29%), Positives = 158/324 (48%), Gaps = 38/324 (11%)
Query: 4 MIVLKFGGSSVKN--DFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYA----KTFDS 57
M +LKFGG+S+ N F S+ + + ++AVV+SA IT+ L+K K
Sbjct: 1 MKLLKFGGTSLANAEKFLSVSSIIEENTQTDQIAVVLSAPAKITNYLVKIIENTIKNNQI 60
Query: 58 KYAIKIADSYVKFARTNGVDPNILSPH-----------------IQELFNPPSLPKDALT 100
+ +A++ N ++ PH IQ + P D +
Sbjct: 61 LETVHLAENIFMQLINNFLNIQSNFPHKEIEKIIKKEFNELKNIIQGILLLKQCP-DNIR 119
Query: 101 DYILSIGELLSAVIFAEVVEGQ-----VIYPWELFSAYG-KFGDGFIDLKKSKKNAKIIY 154
I+S GE+LS I +++ + +I P + A G + D +D+ +SKKN + +
Sbjct: 120 AIIISRGEILSVFIMKSILQSKNYNVTIINPVKNLVAIGDNYLDSTVDISESKKNIQNMN 179
Query: 155 EVIDSGKIPIVPGFVGG-MDGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTAD 213
I+ I ++ GF+ G D V LGR GSDYSA L L++ I ++V+G+FT+D
Sbjct: 180 --INQSNIILMAGFIAGNKDKKLVVLGRNGSDYSAAVLAACLDANCCEIWTDVDGVFTSD 237
Query: 214 PKLVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWR-MGTVIS 272
P+ VP+ARL+ +SY+EA+ + G K + + E + KI L TNN + +GT+I
Sbjct: 238 PRKVPNARLLKSISYQEAMELSYFGAKVLHPRTIEPIAQFKIPCLIKNTNNVKSIGTLIC 297
Query: 273 NRTSR----MPLMTYKDGLLLINV 292
+ + +T+ D + + N+
Sbjct: 298 EQNCSEKDFLKGVTHLDEIAMFNI 321
>pir||C46665 aspartate kinase (EC 2.7.2.4) I - Bacillus subtilis
>gi|142829|gb|AAA22384.1| (L08471) aspartokinase I
[Bacillus subtilis]
Length = 404
Score = 106 bits (262), Expect = 4e-22
Identities = 86/280 (30%), Positives = 140/280 (49%), Gaps = 37/280 (13%)
Query: 3 KMIVLKFGGSSVKNDFHEAVSL---TKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKY 59
K+IV KFGG+SVK+D ++L ++I E +V VVVSA+ D YA DS
Sbjct: 2 KIIVQKFGGTSVKDDKGRKLALGHIKEAISEGYKVVVVVSAMGRKGD---PYAT--DSLL 56
Query: 60 AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVV 119
+ D + +SP Q+L +LS GE +S+V+F ++
Sbjct: 57 GLLYGDQ------------SAISPREQDL--------------LLSCGETISSVVFTSML 90
Query: 120 EGQVIYPWELFSAYGKF--GDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMD-GYR 176
+ L A F D + K + + ++ V+ + +V GF G + G
Sbjct: 91 LDNGVKAAALTGAQAGFLTNDQHTNAKIIEMKPERLFSVLANHDAVVVAGFQGATEKGDT 150
Query: 177 VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAK 236
T+GRGGSD SA ALG +++E + I ++VEG+ TADP++V +A+ +P ++Y E A
Sbjct: 151 TTIGRGGSDTSAAALGAAVDAEYIDIFTDVEGVMTADPRVVENAKPLPVVTYTEICNLAY 210
Query: 237 HGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTS 276
G K I +A E+A + K+ + T + GT++++ S
Sbjct: 211 QGAKVISPRAVEIAMQAKVPIRVRSTYSNDKGTLVTSHHS 250
>sp|Q04795|AK1_BACSU ASPARTOKINASE 1 (ASPARTOKINASE I) (ASPARTATE KINASE 1) [CONTAINS:
ASPARTOKINASE I ALPHA SUBUNIT; ASPARTOKINASE I BETA
SUBUNIT] >gi|2634048|emb|CAB13549.1| (Z99112)
aspartokinase I (alpha and beta subunits) [Bacillus
subtilis]
Length = 404
Score = 106 bits (262), Expect = 4e-22
Identities = 86/280 (30%), Positives = 140/280 (49%), Gaps = 37/280 (13%)
Query: 3 KMIVLKFGGSSVKNDFHEAVSL---TKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKY 59
K+IV KFGG+SVK+D ++L ++I E +V VVVSA+ D YA DS
Sbjct: 2 KIIVQKFGGTSVKDDKGRKLALGHIKEAISEGYKVVVVVSAMGRKGD---PYAT--DSLL 56
Query: 60 AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVV 119
+ D + +SP Q+L +LS GE +S+V+F ++
Sbjct: 57 GLLYGDQ------------SAISPREQDL--------------LLSCGETISSVVFTSML 90
Query: 120 EGQVIYPWELFSAYGKF--GDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMD-GYR 176
+ L A F D + K + + ++ V+ + +V GF G + G
Sbjct: 91 LDNGVKAAALTGAQAGFLTNDQHTNAKIIEMKPERLFSVLANHDAVVVAGFQGATEKGDT 150
Query: 177 VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAK 236
T+GRGGSD SA ALG +++E + I ++VEG+ TADP++V +A+ +P ++Y E A
Sbjct: 151 TTIGRGGSDTSAAALGAAVDAEYIDIFTDVEGVMTADPRVVENAKPLPVVTYTEICNLAY 210
Query: 237 HGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTS 276
G K I +A E+A + K+ + T + GT++++ S
Sbjct: 211 QGAKVISPRAVEIAMQAKVPIRVRSTYSNDKGTLVTSHHS 250
>pir||E81405 aspartate kinase (EC 2.7.2.4) alpha and beta chains Cj0582
[imported] - Campylobacter jejuni (strain NCTC 11168)
>gi|6968049|emb|CAB75218.1| (AL139075) aspartokinase,
alpha and beta subunits [Campylobacter jejuni]
Length = 400
Score = 105 bits (259), Expect = 1e-21
Identities = 94/326 (28%), Positives = 157/326 (47%), Gaps = 48/326 (14%)
Query: 4 MIVLKFGGSSVKN-DFHEAVS--LTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
+IV K+GG+SV + EAV+ + +S + ++ VVVSA+ G+T+ LI+ A+ F
Sbjct: 2 LIVQKYGGTSVGTLERIEAVANRVIQSAQQGNQLVVVVSAMSGVTNTLIEQAEYFSKT-- 59
Query: 61 IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
NG D D +LS GE +++ + + +
Sbjct: 60 ------------PNGKD----------------------MDMLLSSGERVTSALLS-IAL 84
Query: 121 GQVIYPWELFSAY--GKFGDG-FIDLKKSKKNAKIIYEVIDSGKIPIVPGFVG-GMDGYR 176
+ P FS G D F + + K I + +GKI ++ GF G +G
Sbjct: 85 NEKGCPAISFSGRKAGIITDSVFTKARIHHIDTKAIKSELQNGKIVVIAGFQGVDEEGNV 144
Query: 177 VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAK 236
TLGRGGSD SAVA+ LN++L I ++V+G++T DP++ P A+ + +SYEE L A
Sbjct: 145 TTLGRGGSDLSAVAVAGALNADLCEIYTDVDGVYTTDPRIEPKAKKLDKISYEEMLELAS 204
Query: 237 HGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDGLLLINVEEEL 296
G K +Q ++ ELAK+ + ++ + N GT+I+ + G+ L + +
Sbjct: 205 LGAKVLQNRSVELAKKLNVNLVTRSSFNNNEGTMITKEDGMEQALV--SGIALDKNQARV 262
Query: 297 EYRVIDEGP--FWKLYDVPGNEGIRI 320
R I++ P +++ V NE I +
Sbjct: 263 TLRNIEDKPGIAAEIFSVLANENINV 288
>pir||H72364 aspartokinase II - Thermotoga maritima (strain MSB8)
>gi|4981061|gb|AAD35632.1|AE001729_12 (AE001729)
aspartokinase II [Thermotoga maritima]
Length = 739
Score = 104 bits (256), Expect = 2e-21
Identities = 87/310 (28%), Positives = 152/310 (48%), Gaps = 64/310 (20%)
Query: 4 MIVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAV----VVSALKGITDMLIKYAKTFDSKY 59
++V+KFGG+++ +D + + + I + K+ V V+SA+ TD LI+ AKT D
Sbjct: 340 VVVMKFGGAAI-SDVEKLEKVAEKIIKRKKSGVKPVVVLSAMGDTTDHLIELAKTIDE-- 396
Query: 60 AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVV 119
+P +EL D +LS GE+ S + + +
Sbjct: 397 ----------------------NPDPREL------------DLLLSTGEIQSVALMSIAL 422
Query: 120 EGQVIYPWELFSAYG---------KFGDG-FIDLKKSKKNAKIIYEVIDSGKIPIVPGFV 169
+ ++ S G ++G ID+ N II + IP+V GF
Sbjct: 423 RKR---GYKAISFTGNQLKIITDKRYGSARIIDI-----NTDIISRYLKQDFIPVVAGFQ 474
Query: 170 GGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSY 228
G + G TLGRGGSD +A+AL L ++L + +V+G++TADP++V AR+I LS+
Sbjct: 475 GITETGDITTLGRGGSDLTAIALAYSLGADLCELYKDVDGVYTADPRIVKDARVIKELSW 534
Query: 229 EEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTS-RMPL---MTYK 284
EE + ++HG + +Q +AAE A++ + +L + GT+I T P+ +T++
Sbjct: 535 EEMIELSRHGAQVLQARAAEFARKYGVKVLIKNAHKETRGTLIWEGTKVENPIVRAVTFE 594
Query: 285 DGLLLINVEE 294
DG+ + +++
Sbjct: 595 DGMAKVVLKD 604
>sp|P08660|AK3_ECOLI LYSINE-SENSITIVE ASPARTOKINASE III (ASPARTATE KINASE III)
>gi|7428061|pir||KIECD3 aspartate kinase (EC 2.7.2.4)
III, lysine-sensitive - Escherichia coli
>gi|396359|gb|AAC43118.1| (U00006) aspartokinase III
[Escherichia coli] >gi|1790455|gb|AAC76994.1| (AE000475)
aspartokinase III, lysine sensitive [Escherichia coli
K12]
Length = 449
Score = 103 bits (255), Expect = 3e-21
Identities = 89/300 (29%), Positives = 151/300 (49%), Gaps = 22/300 (7%)
Query: 1 MRKMIVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAVVV-SALKGITDMLIKYAKTFDSKY 59
M +++V KFGG+SV DF + + V +VV SA GIT++L+ A+ +
Sbjct: 1 MSEIVVSKFGGTSVA-DFDAMNRSADIVLSDANVRLVVLSASAGITNLLVALAEGLEPGE 59
Query: 60 AIKIADSY--VKFARTNGVD-PNILSPHIQELFNPPSLPKDA--------LTDYILSIGE 108
+ D+ ++FA + PN++ I+ L ++ +A LTD ++S GE
Sbjct: 60 RFEKLDAIRNIQFAILERLRYPNVIREEIERLLENITVLAEAAALATSPALTDELVSHGE 119
Query: 109 LLSAVIFAEVV-EGQVIYPW----ELFSAYGKFGDGFIDLKKSKKNAKI-IYEVIDSGKI 162
L+S ++F E++ E V W ++ +FG D+ + A + + ++ G +
Sbjct: 120 LMSTLLFVEILRERDVQAQWFDVRKVMRTNDRFGRAEPDIAALAELAALQLLPRLNEGLV 179
Query: 163 PIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSAR 221
I GF+G + G TLGRGGSDY+A L L++ V I ++V GI+T DP++V +A+
Sbjct: 180 -ITQGFIGSENKGRTTTLGRGGSDYTAALLAEALHASRVDIWTDVPGIYTTDPRVVSAAK 238
Query: 222 LIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRM-GTVISNRTSRMPL 280
I +++ EA A G K + A I + G + + R GT++ N+T PL
Sbjct: 239 RIDEIAFAEAAEMATFGAKVLHPATLLPAVRSDIPVFVGSSKDPRAGGTLVCNKTENPPL 298
>gb|AAA24095.1| (M11812) aspartokinase III [Escherichia coli]
Length = 449
Score = 103 bits (254), Expect = 4e-21
Identities = 89/300 (29%), Positives = 151/300 (49%), Gaps = 22/300 (7%)
Query: 1 MRKMIVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAVVV-SALKGITDMLIKYAKTFDSKY 59
M +++V KFGG+SV DF + + V +VV SA GIT++L+ A+ +
Sbjct: 1 MSEIVVSKFGGTSVA-DFDAMNRSADIVLSDANVRLVVLSASAGITNLLVALAEGLEPCE 59
Query: 60 AIKIADSY--VKFARTNGVD-PNILSPHIQELFNPPSLPKDA--------LTDYILSIGE 108
+ D+ ++FA + PN++ I+ L ++ +A LTD ++S GE
Sbjct: 60 RFEKLDAIRNIQFAILERLRYPNVIREEIERLLENITVLAEAAALATSPALTDELVSHGE 119
Query: 109 LLSAVIFAEVV-EGQVIYPW----ELFSAYGKFGDGFIDLKKSKKNAKI-IYEVIDSGKI 162
L+S ++F E++ E V W ++ +FG D+ + A + + ++ G +
Sbjct: 120 LMSTLLFVEILRERDVQAQWFDVRKVMRTNDRFGRAEPDIAALAELAALQLLPRLNEGLV 179
Query: 163 PIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSAR 221
I GF+G + G TLGRGGSDY+A L L++ V I ++V GI+T DP++V +A+
Sbjct: 180 -ITQGFIGSENKGRTTTLGRGGSDYTAALLAEALHASRVDIWTDVPGIYTTDPRVVSAAK 238
Query: 222 LIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRM-GTVISNRTSRMPL 280
I +++ EA A G K + A I + G + + R GT++ N+T PL
Sbjct: 239 RIDEIAFAEAAEMATFGAKVLHPATLLPAVRSDIPVFVGSSKDPRAGGTLVCNKTENPPL 298
>sp|O25827|AK_HELPY ASPARTOKINASE (ASPARTATE KINASE) >gi|7434553|pir||E64673
aspartokinase - Helicobacter pylori (strain 26695)
>gi|2314392|gb|AAD08274.1| (AE000628) aspartokinase
(lysC) [Helicobacter pylori 26695]
Length = 405
Score = 102 bits (251), Expect = 8e-21
Identities = 81/277 (29%), Positives = 133/277 (47%), Gaps = 48/277 (17%)
Query: 4 MIVLKFGGSS---VKNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
+IV K+GG+S ++ + A + +S+ +V VVVSA+ G TD L+++ K F
Sbjct: 2 LIVQKYGGTSMGSIERIHNVAQRVLESVTLGHQVVVVVSAMSGETDRLLEFGKNFSH--- 58
Query: 61 IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
+P+ +E+ D I+S+GEL+S+ + +E
Sbjct: 59 ---------------------NPNKREM------------DRIVSVGELVSSAALSMALE 85
Query: 121 GQVIYPWELFSAYGK-----FGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGG-MDG 174
Y S GK F + + K I E+++ I ++ GF G + G
Sbjct: 86 R---YGHRAISLSGKEAGILTSSHFQNAVIQSIDTKRITELLEKNYIVVIAGFQGADIQG 142
Query: 175 YRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIA 234
TLGRGGSD SAVAL L + L I ++V+G++T DP++ A+ I +SY+E L
Sbjct: 143 ETTTLGRGGSDLSAVALAGALKAHLCEIYTDVDGVYTTDPRIEEKAQKIAQISYDEMLEL 202
Query: 235 AKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVI 271
A G K + ++ ELAK+ + ++ + N GT+I
Sbjct: 203 ASMGAKVLLNRSVELAKKLSVKLVTRNSFNHSEGTLI 239
>dbj|BAB06119.1| (AP001515) aspartokinase I (alpha and beta subunits) [Bacillus
halodurans]
Length = 411
Score = 99.8 bits (245), Expect = 4e-20
Identities = 88/297 (29%), Positives = 138/297 (45%), Gaps = 49/297 (16%)
Query: 3 KMIVLKFGGSSVKN-DFHE--AVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKY 59
K+I+ KFGG+SVK + E A + K++ +V VVVSA+
Sbjct: 2 KIIIQKFGGTSVKTAEVREMAAKHVEKAVEGGYKVVVVVSAMG----------------- 44
Query: 60 AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVV 119
+ D Y VD ++ Q+L ++S GE++S+V+F E++
Sbjct: 45 --RSGDPYATDTLLQLVDTKTIAKREQDL--------------LVSCGEIISSVVFTELL 88
Query: 120 EGQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGK-------IPIVPGFVG-G 171
+ I + A F + NAKI+ +D K + +V GF G
Sbjct: 89 LKKGIQATAMTGAQAGF-----RTNEEFTNAKIVDMKVDRLKKTLVHQDVVVVAGFQGQS 143
Query: 172 MDGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEA 231
G TLGRGGSD SA ALG L++E V I ++VEGI TADP++V AR + ++Y E
Sbjct: 144 PTGETTTLGRGGSDTSATALGAALDAEWVDIFTDVEGIMTADPRIVSEARPLDTMTYNEV 203
Query: 232 LIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDGLL 288
A G K I +A E+A + KI + T + GT++++ + +D ++
Sbjct: 204 CNMAYQGAKVIHPRAVEIAMQAKIPIHIRSTYSDGKGTLVTSMLTEAGARDVQDRII 260
>sp|Q9ZJZ7|AK_HELPJ ASPARTOKINASE (ASPARTATE KINASE) >gi|7434552|pir||H71843
aspartokinase 2 alpha and beta chains - Helicobacter
pylori (strain J99) >gi|4155744|gb|AAD06723.1|
(AE001542) ASPARTOKINASE 2 ALPHA AND BETA SUBUNITS
[Helicobacter pylori J99]
Length = 405
Score = 97.5 bits (239), Expect = 2e-19
Identities = 82/279 (29%), Positives = 133/279 (47%), Gaps = 52/279 (18%)
Query: 4 MIVLKFGGSS---VKNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
+IV K+GG+S ++ + A + +S+ +V VVVSA+ G TD L+++ K F
Sbjct: 2 LIVQKYGGTSMGSIERIHNVAQRVLESVKLGHQVVVVVSAMSGETDRLLEFGKNFSH--- 58
Query: 61 IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
+P+ +E+ D I+S GE +S+ + +E
Sbjct: 59 ---------------------NPNKREM------------DRIVSAGEWISSAALSMALE 85
Query: 121 GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKI-------IYEVIDSGKIPIVPGFVGG-M 172
Y S GK + I +NA I I E+++ I ++ GF G +
Sbjct: 86 R---YGHRAISLSGK--EAGILTSSHFQNAVIQSIDTQRITELLEKNYIVVIAGFQGADI 140
Query: 173 DGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEAL 232
G TLGRGGSD SAVAL L + L I ++V+G++T DP++ A+ I +SY+E L
Sbjct: 141 QGETTTLGRGGSDLSAVALAGALKAHLCEIYTDVDGVYTTDPRIEEKAQKIAQISYDEML 200
Query: 233 IAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVI 271
A G K + ++ ELAK+ + ++ + N GT+I
Sbjct: 201 ELASMGAKVLLNRSVELAKKLSVKLVTRNSFNHSEGTLI 239
>sp|P44505|AKH_HAEIN BIFUNCTIONAL ASPARTOKINASE/HOMOSERINE DEHYDROGENASE (AK-HD)
[INCLUDES: ASPARTOKINASE ; HOMOSERINE DEHYDROGENASE ]
>gi|1073872|pir||A64048 aspartate kinase (EC 2.7.2.4) I
/ homoserine dehydrogenase (EC 1.1.1.3) - Haemophilus
influenzae (strain Rd KW20) >gi|1573040|gb|AAC21767.1|
(U32694) aspartokinase I / homoserine dehydrogenase I
(thrA) [Haemophilus influenzae Rd]
Length = 815
Score = 97.1 bits (238), Expect = 3e-19
Identities = 93/322 (28%), Positives = 150/322 (45%), Gaps = 35/322 (10%)
Query: 4 MIVLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAK------TF 55
M VLKFGG+S+ N F +A L + E++ A V+SA IT+ L+ ++ +
Sbjct: 1 MRVLKFGGTSLANPERFSQAAKLIEQAHLEEQAAGVLSAPAKITNHLVALSEKAALNQST 60
Query: 56 DSKY--AIKIADSYVKFART-------NGVDPNILSPHIQ-----ELFNPPSLPKDALTD 101
D+ + AI+I + + T NG I + +Q E +DA+
Sbjct: 61 DTHFNEAIEIFYNIINGLHTENNQFDLNGTKALIDAEFVQIKGLLEEIRQAGKVEDAVKA 120
Query: 102 YILSIGELLSAVIFAEVVEGQ-----VIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEV 156
I GE LS + E + ++ P + A G + + +++++S K ++
Sbjct: 121 TIDCRGEKLSIAMMKAWFEARGYSVHIVDPVKQLLAKGGYLESSVEIEESTK--RVDAAN 178
Query: 157 IDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPK 215
I K+ ++ GF G + G V LGR GSDYSA L L + + I ++V+G++T DP+
Sbjct: 179 IAKDKVVLMAGFTAGNEKGELVLLGRNGSDYSAACLAACLGASVCEIWTDVDGVYTCDPR 238
Query: 216 LVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNN-WRMGTVISNR 274
LVP ARL+P LSY EA+ + G K I + + I + T N G++I
Sbjct: 239 LVPDARLLPTLSYREAMELSYFGAKVIHPRTIGPLLPQNIPCVIKNTGNPSAPGSIIDGN 298
Query: 275 TSRMPL----MTYKDGLLLINV 292
L +T D L + NV
Sbjct: 299 VKSESLQVKGITNLDNLAMFNV 320
>dbj|BAA38474.1| (D10385) aspartokinase I-homoserine dehydrogenase I [Serratia
marcescens]
Length = 819
Score = 97.1 bits (238), Expect = 3e-19
Identities = 101/351 (28%), Positives = 163/351 (45%), Gaps = 37/351 (10%)
Query: 4 MIVLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYA-KTFDSKYA 60
M VLKFGG+SV N F + +S + +VA V+SA IT+ L+ KT +
Sbjct: 1 MRVLKFGGTSVANAERFLRVADIMESNARQGQVATVLSAPAKITNHLVAMIDKTVAGQDI 60
Query: 61 I-KIADSYVKFA----------------RTNGVDPNILSPHIQELFNPPSLPK--DALTD 101
+ ++D+ FA R GV + Q L L + D++
Sbjct: 61 LPNMSDAERIFADLLSGLAQALPGFEYDRLKGVVDQEFAQLKQVLHGVSLLGQCPDSVNA 120
Query: 102 YILSIGELLSAVIFAEVVEGQ-----VIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEV 156
I+ GE LS I V + VI P E A G + + +D+ +S +I
Sbjct: 121 AIICRGEKLSIAIMEGVFRAKGYPVTVINPVEKLLAQGHYLESTVDIAES--TLRIAAAA 178
Query: 157 IDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPK 215
I + I ++ GF G D G V LGR GSDYSA L L ++ I ++V+G++T DP+
Sbjct: 179 IPADHIVLMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPR 238
Query: 216 LVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRM-GTVI--S 272
VP ARL+ +SY+EA+ + G K + + + +I L T+N + GT+I
Sbjct: 239 TVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTSNPQAPGTLIGKD 298
Query: 273 NRTSRMPL--MTYKDGLLLINVEEELEYRVIDEGPFWKLYDVPGNEGIRII 321
+ + MP+ +T + + +INV ++D +++ V GI ++
Sbjct: 299 STDADMPVKGITNLNNMAMINVSGPGMKGMVDMAA--RVFAVMSRAGISVV 347
>sp|P27725|AK1H_SERMA BIFUNCTIONAL ASPARTOKINASE/HOMOSERINE DEHYDROGENASE I (AKI-HDI)
[INCLUDES: ASPARTOKINASE I ; HOMOSERINE DEHYDROGENASE I
] >gi|421254|pir||B47057 aspartate kinase (EC 2.7.2.4) I
/ homoserine dehydrogenase (EC 1.1.1.3) I - Serratia
marcescens >gi|47273|emb|CAA43212.1| (X60821) aspartate
kinase [Serratia marcescens]
Length = 819
Score = 96.7 bits (237), Expect = 4e-19
Identities = 97/322 (30%), Positives = 152/322 (47%), Gaps = 35/322 (10%)
Query: 4 MIVLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYA-KTFDSKYA 60
M VLKFGG+SV N F + +S + +VA V+SA IT+ L+ KT +
Sbjct: 1 MRVLKFGGTSVANAERFLRVADIMESNARQGQVATVLSAPAKITNHLVAMIDKTVAGQDI 60
Query: 61 I-KIADSYVKFA----------------RTNGVDPNILSPHIQELFNPPSLPK--DALTD 101
+ ++D+ FA R GV + Q L L + D++
Sbjct: 61 LPNMSDAERIFADLLSGLAQALPGFEYDRLKGVVDQEFAQLKQVLHGVSLLGQCPDSVNA 120
Query: 102 YILSIGELLSAVIFAEVVEGQ-----VIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEV 156
I+ GE LS I V + VI P E A G + + +D+ +S +I
Sbjct: 121 AIICRGEKLSIAIMEGVFRAKGYPVTVINPVEKLLAQGHYLESTVDIAES--TLRIAAAA 178
Query: 157 IDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPK 215
I + I ++ GF G D G V LGR GSDYSA L L ++ I ++V+G++T DP+
Sbjct: 179 IPADHIVLMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPR 238
Query: 216 LVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRM-GTVI--S 272
VP ARL+ +SY+EA+ + G K + + + +I L T+N + GT+I
Sbjct: 239 TVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTSNPQAPGTLIGKD 298
Query: 273 NRTSRMPL--MTYKDGLLLINV 292
+ + MP+ +T + + +INV
Sbjct: 299 STDADMPVKGITNLNNMAMINV 320
>dbj|BAA38477.1| (D10386) aspartokinase I-homoserine dehydrogenase I [Serratia
marcescens]
Length = 819
Score = 96.7 bits (237), Expect = 4e-19
Identities = 97/322 (30%), Positives = 152/322 (47%), Gaps = 35/322 (10%)
Query: 4 MIVLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYA-KTFDSKYA 60
M VLKFGG+SV N F + +S + +VA V+SA IT+ L+ KT +
Sbjct: 1 MRVLKFGGTSVANAERFLRVADIMESNARQGQVATVLSAPAKITNHLVAMIDKTVAGQDI 60
Query: 61 I-KIADSYVKFA----------------RTNGVDPNILSPHIQELFNPPSLPK--DALTD 101
+ ++D+ FA R GV + Q L L + D++
Sbjct: 61 LPNMSDAERIFADLLSGLAQALPGFEYDRLKGVVDQEFAQLKQVLHGVSLLGQCPDSVNA 120
Query: 102 YILSIGELLSAVIFAEVVEGQ-----VIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEV 156
I+ GE LS I V + VI P E A G + + +D+ +S +I
Sbjct: 121 AIICRGEKLSIAIMEGVFRAKGYPVTVINPVEKLLAQGHYLESTVDIAES--TLRIAAAA 178
Query: 157 IDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPK 215
I + I ++ GF G D G V LGR GSDYSA L L ++ I ++V+G++T DP+
Sbjct: 179 IPADHIVLMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPR 238
Query: 216 LVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRM-GTVI--S 272
VP ARL+ +SY+EA+ + G K + + + +I L T+N + GT+I
Sbjct: 239 TVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTSNPQAPGTLIGKD 298
Query: 273 NRTSRMPL--MTYKDGLLLINV 292
+ + MP+ +T + + +INV
Sbjct: 299 STDADMPVKGITNLNNMAMINV 320
>dbj|BAA38480.1| (D10387) aspartokinase I-homoserine dehydrogenase I [Serratia
marcescens]
Length = 819
Score = 96.7 bits (237), Expect = 4e-19
Identities = 97/322 (30%), Positives = 152/322 (47%), Gaps = 35/322 (10%)
Query: 4 MIVLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYA-KTFDSKYA 60
M VLKFGG+SV N F + +S + +VA V+SA IT+ L+ KT +
Sbjct: 1 MRVLKFGGTSVANAERFLRVADIMESNARQGQVATVLSAPAKITNHLVAMIDKTVAGQDI 60
Query: 61 I-KIADSYVKFA----------------RTNGVDPNILSPHIQELFNPPSLPK--DALTD 101
+ ++D+ FA R GV + Q L L + D++
Sbjct: 61 LPNMSDAERIFADLLSGLAQALPGFEYDRLKGVVDQEFAQLKQVLHGVSLLGQCPDSVNA 120
Query: 102 YILSIGELLSAVIFAEVVEGQ-----VIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEV 156
I+ GE LS I V + VI P E A G + + +D+ +S +I
Sbjct: 121 AIICRGEKLSIAIMEGVFRAKGYPVTVINPVEKLLAQGHYLESTVDIAES--TLRIAAAA 178
Query: 157 IDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPK 215
I + I ++ GF G D G V LGR GSDYSA L L ++ I ++V+G++T DP+
Sbjct: 179 IPADHIVLMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPR 238
Query: 216 LVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRM-GTVI--S 272
VP ARL+ +SY+EA+ + G K + + + +I L T+N + GT+I
Sbjct: 239 TVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTSNPQAPGTLIGKD 298
Query: 273 NRTSRMPL--MTYKDGLLLINV 292
+ + MP+ +T + + +INV
Sbjct: 299 STDADMPVKGITNLNNMAMINV 320
>pir||DEECK thrA bifunctional enzyme - Escherichia coli
>gi|537245|gb|AAA97301.1| (U14003) aspartokinase
I-homoserine dehydrogenase I [Escherichia coli]
>gi|1786183|gb|AAC73113.1| (AE000111) aspartokinase I,
homoserine dehydrogenase I [Escherichia coli K12]
Length = 820
Score = 95.6 bits (234), Expect = 8e-19
Identities = 85/289 (29%), Positives = 135/289 (46%), Gaps = 30/289 (10%)
Query: 4 MIVLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYA-KTFDSKYA 60
M VLKFGG+SV N F + +S + +VA V+SA IT+ L+ KT + A
Sbjct: 1 MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTISGQDA 60
Query: 61 I-KIADSYVKFART-----------------NGVDPNILS-PHIQELFNPPSLPKDALTD 101
+ I+D+ FA VD H+ + D++
Sbjct: 61 LPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIKHVLHGISLLGQCPDSINA 120
Query: 102 YILSIGELLSAVIFAEVVEGQ-----VIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEV 156
++ GE +S I A V+E + VI P E A G + + +D+ +S + +I
Sbjct: 121 ALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHYLESTVDIAESTR--RIAASR 178
Query: 157 IDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPK 215
I + + ++ GF G + G V LGR GSDYSA L L ++ I ++V+G++T DP+
Sbjct: 179 IPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPR 238
Query: 216 LVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNN 264
VP ARL+ +SY+EA+ + G K + + + +I L T N
Sbjct: 239 QVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGN 287
>sp|P00561|AK1H_ECOLI BIFUNCTIONAL ASPARTOKINASE/HOMOSERINE DEHYDROGENASE I (AKI-HDI)
[INCLUDES: ASPARTOKINASE I ; HOMOSERINE DEHYDROGENASE I
]
Length = 820
Score = 94.8 bits (232), Expect = 1e-18
Identities = 85/289 (29%), Positives = 134/289 (45%), Gaps = 30/289 (10%)
Query: 4 MIVLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYA-KTFDSKYA 60
M VLKFGG+SV N F + +S + +VA V+SA IT+ L+ KT + A
Sbjct: 1 MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTISGQDA 60
Query: 61 I-KIADSYVKFART-----------------NGVDPNILS-PHIQELFNPPSLPKDALTD 101
+ I+D+ FA VD H+ + D++
Sbjct: 61 LPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIKHVLHGISLLGQCPDSINA 120
Query: 102 YILSIGELLSAVIFAEVVEGQ-----VIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEV 156
++ GE +S I A V+E + VI P E A G + + +D+ +S + +I
Sbjct: 121 ALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHYLESTVDIAESTR--RIAASR 178
Query: 157 IDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPK 215
I + + ++ GF G + G V LGR GSDYSA L L ++ I ++V G++T DP+
Sbjct: 179 IPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVNGVYTCDPR 238
Query: 216 LVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNN 264
VP ARL+ +SY+EA+ + G K + + + +I L T N
Sbjct: 239 QVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGN 287
>sp|P41403|AK_MYCSM ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: ASPARTOKINASE ALPHA
SUBUNIT (ASK-ALPHA); ASPARTOKINASE BETA SUBUNIT
(ASK-BETA)] >gi|421602|pir||S31801 aspartate kinase (EC
2.7.2.4) alpha chain - Mycobacterium smegmatis
>gi|7434561|pir||S42422 aspartate kinase (EC 2.7.2.4)
alpha chain - Mycobacterium smegmatis
>gi|581352|emb|CAA78984.1| (Z17372) aspartokinase
[Mycobacterium smegmatis]
Length = 421
Score = 94.4 bits (231), Expect = 2e-18
Identities = 92/325 (28%), Positives = 146/325 (44%), Gaps = 64/325 (19%)
Query: 4 MIVLKFGGSSVKNDFHEAVSLTKSIFEEK----EVAVVVSALKGITDMLIKYAKTFDSKY 59
++V K+GGSSV D + + I E K +V VVVSA+ TD L+ A+
Sbjct: 3 LVVQKYGGSSVA-DAERIRRVAERIVETKKAGNDVVVVVSAMGDTTDDLLDLARQV---- 57
Query: 60 AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVV 119
+P P++ D +L+ GE +S + A +
Sbjct: 58 ------------------------------SPAPPPREM--DMLLTAGERISNALVAMAI 85
Query: 120 EGQVIYPWELF-SAYGKFGDGFIDLKKSKKNAKII-------YEVIDSGKIPIVPGFVGG 171
E S G G + NAKII + +D G+I +V GF G
Sbjct: 86 ESLGAQARSFTGSQAGVITTG------THGNAKIIDVTPGRLRDALDEGQIVLVAGFQGV 139
Query: 172 MDGYR--VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYE 229
+ TLGRGGSD +AVA+ L++++ I ++V+GIFTADP++VP+AR + +S+E
Sbjct: 140 SQDSKDVTTLGRGGSDTTAVAVAAALDADVCEIYTDVDGIFTADPRIVPNARHLDTVSFE 199
Query: 230 EALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDGLLL 289
E L A G K + + E A+ + + + + + GT++ +P+ +D +L
Sbjct: 200 EMLEMAACGAKVLMLRCVEYARRYNVPIHVRSSYSDKPGTIVKGSIEDIPM---EDAILT 256
Query: 290 INVEEELEYRVIDEGPFWKLYDVPG 314
+ E +V G L DVPG
Sbjct: 257 GVAHDRSEAKVTVVG----LPDVPG 277
>pir||E72715 probable aspartate kinase APE1140 - Aeropyrum pernix (strain K1)
>gi|5104810|dbj|BAA80125.1| (AP000060) 473aa long
hypothetical aspartate kinase [Aeropyrum pernix]
Length = 473
Score = 94.0 bits (230), Expect = 2e-18
Identities = 78/261 (29%), Positives = 128/261 (48%), Gaps = 28/261 (10%)
Query: 4 MIVLKFGGSSVKND--FHEAVSLTKSIFEEK-EVAVVVSALKGITDMLIKYAKTFDSKYA 60
++V+KFGGS + F A L + E E VVVSA+KG+TD L+ + D
Sbjct: 27 LVVVKFGGSVLNGSPGFLAAGRLVLGLLESGLEPVVVVSAVKGVTDALLSSFERRDPGVG 86
Query: 61 IKIADSYVKFARTNGVDP------NILSPHIQELFNPPSLPKD---ALTDYILSIGELLS 111
+ +Y+ AR G+ P ++ S + +L + + D ++S GE LS
Sbjct: 87 GAVGKTYLSIARELGLPPESVRDVSLASAEVSKLLWAAEVLGQWTPRVRDLVVSYGERLS 146
Query: 112 AVIFAEV-----VEGQVIYPWEL-FSAYGKFGD-----GFIDLKKSKKNAKIIYEVIDSG 160
A + A + VE + + E G+FGD G+ + ++ + +++ G
Sbjct: 147 AALMAGLLRRLGVEARWLGGGEAGIVTDGEFGDATPLYGYTEGVIRER----LEPMLEEG 202
Query: 161 KIPIVPGFVGGM-DGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPS 219
+P+V GF G +G LGRGGSD +A L L + V + ++V GI + DP++V
Sbjct: 203 VVPVVAGFTGATREGDTTLLGRGGSDLTATLLASALGAGRVVLYTDVPGILSGDPRVVGE 262
Query: 220 ARLIPYLSYEEALIAAKHGMK 240
R + Y+SYEEA A+ G++
Sbjct: 263 PRRVGYMSYEEAWEVARLGLR 283
>emb|CAA23660.1| (V00361) thrA gene [EC 2.7.2.4 and EC 1.1.1.3] [Escherichia coli]
>gi|147979|gb|AAA83914.1| (J01706) aspartokinase
I-homoserine dehydrogenase I [Escherichia coli]
>gi|216435|dbj|BAA01286.1| (D10483) aspartokinase I
[Escherichia coli]
Length = 820
Score = 93.6 bits (229), Expect = 3e-18
Identities = 84/289 (29%), Positives = 134/289 (46%), Gaps = 30/289 (10%)
Query: 4 MIVLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYA-KTFDSKYA 60
M VLKFGG+S+ N F + +S + +VA V+SA IT+ L+ KT + A
Sbjct: 1 MRVLKFGGTSLANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTISGQDA 60
Query: 61 I-KIADSYVKFART-----------------NGVDPNILS-PHIQELFNPPSLPKDALTD 101
+ I+D+ FA VD H+ + D++
Sbjct: 61 LPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIKHVLHGISLLGQCPDSINA 120
Query: 102 YILSIGELLSAVIFAEVVEGQ-----VIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEV 156
++ GE +S I A V+E + VI P E A G + + +D+ +S + +I
Sbjct: 121 ALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHYLESTVDIAESTR--RIAASR 178
Query: 157 IDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPK 215
I + + ++ GF G + G V LGR GSDYSA L L ++ I ++V G++T DP+
Sbjct: 179 IPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVNGVYTCDPR 238
Query: 216 LVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNN 264
VP ARL+ +SY+EA+ + G K + + + +I L T N
Sbjct: 239 QVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGN 287
>sp|P26512|AK_CORGL ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: ASPARTOKINASE ALPHA
SUBUNIT; ASPARTOKINASE BETA SUBUNIT]
>gi|320521|pir||S15276 aspartate kinase (EC 2.7.2.4)
alpha chain - Corynebacterium glutamicum
>gi|580983|emb|CAA40502.1| (X57226) aspartate kinase
[Corynebacterium glutamicum]
Length = 421
Score = 93.2 bits (228), Expect = 4e-18
Identities = 97/340 (28%), Positives = 159/340 (46%), Gaps = 69/340 (20%)
Query: 4 MIVLKFGGSSVKN-----DFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSK 58
++V K+GGSS+++ + E + TK +V VVVSA+ TD L++ A
Sbjct: 3 LVVQKYGGSSLESAERIRNVAERIVATKKA--GNDVVVVVSAMGDTTDELLELA------ 54
Query: 59 YAIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEV 118
A N V P +E+ D +L+ GE +S + A
Sbjct: 55 ------------AAVNPVPP------AREM------------DMLLTAGERISNALVAMA 84
Query: 119 VEGQVIYPWELFSAYGKFGDGFIDLKKSKK--NAKII-------YEVIDSGKIPIVPGFV 169
+E L + F + +++ NA+I+ E +D GKI IV GF
Sbjct: 85 IES-------LGAEAQSFTGSQAGVLTTERHGNARIVDVTPGRVREALDEGKICIVAGFQ 137
Query: 170 GGMDGYR--VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLS 227
G R TLGRGGSD +AVAL LN+++ I S+V+G++TADP++VP+A+ + LS
Sbjct: 138 GVNKETRDVTTLGRGGSDTTAVALAAALNADVCEIYSDVDGVYTADPRIVPNAQKLEKLS 197
Query: 228 YEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDGL 287
+EE L A G K + ++ E A+ + + + + GT+I+ +P+ ++ +
Sbjct: 198 FEEMLELAAVGSKILVLRSVEYARAFNVPLRVRSSYSNDPGTLIAGSMEDIPV---EEAV 254
Query: 288 LLINVEEELEYRVIDEGPFWKLYDVPGNEGIRIIRELHKA 327
L ++ E +V G + D PG E ++ R L A
Sbjct: 255 LTGVATDKSEAKVTVLG----ISDKPG-EAAKVFRALADA 289
>gb|AAD49567.1|AF134837_1 (AF134837) aspartokinase subunit A [Amycolatopsis mediterranei]
Length = 421
Score = 91.3 bits (223), Expect = 2e-17
Identities = 77/291 (26%), Positives = 128/291 (43%), Gaps = 57/291 (19%)
Query: 4 MIVLKFGGSSVKNDFH-----EAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSK 58
++V K+GGSS+++ E + TK +V VV SA+ TD L+ A+
Sbjct: 3 LVVQKYGGSSLESADRIKRVAERIVATKKA--GNDVVVVCSAMGDTTDELLDLAQQV--- 57
Query: 59 YAIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEV 118
NP P + D +L+ GE +S + A
Sbjct: 58 -------------------------------NPA--PPEREMDMLLTAGERISNSLVAMA 84
Query: 119 VEGQVIYPWELFSAYGKF-------GDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGG 171
+ Q W + ID+ S+ + E +D G I +V GF G
Sbjct: 85 IAAQGAEAWSFTGSQAGVVTTSVHGNARIIDVTPSR-----VTEALDQGYIALVAGFQGV 139
Query: 172 MDGYR--VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYE 229
+ TLGRGGSD +AVAL LN+++ I S+V+G++TADP++VP A+ + ++YE
Sbjct: 140 AQDTKDITTLGRGGSDTTAVALAAALNADVCEIYSDVDGVYTADPRVVPDAKKLDTVTYE 199
Query: 230 EALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPL 280
E L A G K + ++ E A+ + + + + + GT ++ +P+
Sbjct: 200 EMLELAASGSKILHLRSVEYARRYGVPIRVRSSYSDKPGTTVTGSIEEIPV 250
>sp|P41398|AK_CORFL ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: ASPARTOKINASE ALPHA
SUBUNIT; ASPARTOKINASE BETA SUBUNIT]
>gi|289909|gb|AAA23293.1| (L16848) aspartokinase
[Corynebacterium flavescens]
Length = 421
Score = 91.3 bits (223), Expect = 2e-17
Identities = 96/340 (28%), Positives = 158/340 (46%), Gaps = 69/340 (20%)
Query: 4 MIVLKFGGSSVKN-----DFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSK 58
++V K+GGSS+++ + E + TK +V VV SA+ TD L++ A
Sbjct: 3 LVVQKYGGSSLESAERIRNVAERIVATKKA--GNDVVVVCSAMGDTTDELLELA------ 54
Query: 59 YAIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEV 118
A N V P +E+ D +L+ GE +S + A
Sbjct: 55 ------------AAVNPVPP------AREM------------DMLLTAGERISNALVAMA 84
Query: 119 VEGQVIYPWELFSAYGKFGDGFIDLKKSKK--NAKII-------YEVIDSGKIPIVPGFV 169
+E L + F + +++ NA+I+ E +D GKI IV GF
Sbjct: 85 IES-------LGAEAQSFTGSQAGVLTTERHGNARIVDVTPGRVREALDEGKICIVAGFQ 137
Query: 170 GGMDGYR--VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLS 227
G R TLGRGGSD +AVAL LN+++ I S+V+G++TADP++VP+A+ + LS
Sbjct: 138 GVNKETRDVTTLGRGGSDTTAVALAAALNADVCEIYSDVDGVYTADPRIVPNAQKLEKLS 197
Query: 228 YEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDGL 287
+EE L A G K + ++ E A+ + + + + GT+I+ +P+ ++ +
Sbjct: 198 FEEMLELAAVGSKILVLRSVEYARAFNVPLRVRSSYSNDPGTLIAGSMEDIPV---EEAV 254
Query: 288 LLINVEEELEYRVIDEGPFWKLYDVPGNEGIRIIRELHKA 327
L ++ E +V G + D PG E ++ R L A
Sbjct: 255 LTGVATDKSEAKVTVLG----ISDKPG-EAAKVFRALADA 289
>sp|P53553|AK2_BACST ASPARTOKINASE 2 (ASPARTOKINASE II) (ASPARTATE KINASE 2) [CONTAINS:
ASPARTOKINASE II ALPHA SUBUNIT; ASPARTOKINASE II BETA
SUBUNIT] >gi|2126845|pir||JC4640 aspartate kinase (EC
2.7.2.4) II - Bacillus stearothermophilus
>gi|928811|gb|AAB06216.1| (L46351) aspartokinase II
[Bacillus stearothermophilus]
Length = 407
Score = 89.3 bits (218), Expect = 6e-17
Identities = 85/284 (29%), Positives = 127/284 (43%), Gaps = 52/284 (18%)
Query: 4 MIVLKFGGSSV---KNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
+IV KFGG+SV + H A + + + + +V VVVSA+ TD L+ AK
Sbjct: 3 IIVQKFGGTSVGSIERIQHVANRVIEEVQKGNDVVVVVSAMGKTTDELVNLAK------- 55
Query: 61 IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
++ N PS + D +LS GE +S + A +
Sbjct: 56 --------------------------QISNHPSKRE---MDMLLSTGEQVSIALLAMSLH 86
Query: 121 GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKI-------IYEVIDSGKIPIVPGFVGGMD 173
+ ++ S G I ++ NA+I I +D G I IV GF G +
Sbjct: 87 EK---GYKAVSLTG--WQAGITTEEMHGNARIMNIDTTRIRRCLDEGAIVIVAGFQGVTE 141
Query: 174 -GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEAL 232
G TLGRGGSD +AVAL L +E I ++V G+FT DP+ V +AR I +SY+E L
Sbjct: 142 TGEITTLGRGGSDTTAVALAAALKAEKCDIYTDVTGVFTTDPRYVKTARKIKEISYDEML 201
Query: 233 IAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTS 276
A G + +A E AK ++ + + GT++ S
Sbjct: 202 ELANLGAGVLHPRAVEFAKNYEVPLEVRSSMENERGTMVKEEVS 245
>sp|Q59229|AK2_BACSP ASPARTOKINASE 2 (ASPARTOKINASE II) (ASPARTATE KINASE 2) [CONTAINS:
ASPARTOKINASE II ALPHA SUBUNIT; ASPARTOKINASE II BETA
SUBUNIT] >gi|1075793|pir||A48946 aspartate kinase (EC
2.7.2.4) II precursor - Bacillus sp. (strain MGA3)
>gi|142540|gb|AAA22251.1| (M93419) aspartokinase II
[Bacillus sp.]
Length = 411
Score = 88.9 bits (217), Expect = 8e-17
Identities = 85/284 (29%), Positives = 125/284 (43%), Gaps = 52/284 (18%)
Query: 4 MIVLKFGGSSVKNDFHEAVSLTKSIFEEK----EVAVVVSALKGITDMLIKYAKTFDSKY 59
+IV KFGG+SV +++ + EEK +V VVVSA+ TD L+ AK +
Sbjct: 3 LIVQKFGGTSV-GSVERILNVANRVIEEKKNGNDVVVVVSAMGKTTDELVDLAKQISA-- 59
Query: 60 AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGE-----LLSAVI 114
+PP D L L+ GE LL+ +
Sbjct: 60 ------------------------------HPPKREMDML----LTTGEQVTISLLAMAL 85
Query: 115 FAEVVEGQVIYPWEL-FSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVG-GM 172
+ E W+ + FG+ I +++K I + ++ GKI +V GF G
Sbjct: 86 NEKGYEAISYTGWQAGITTEPVFGNARILNIETEK----IQKQLNEGKIVVVAGFQGIDE 141
Query: 173 DGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEAL 232
G TLGRGGSD +AVAL L +E I ++V G+FT DP+ V SAR + +SY+E L
Sbjct: 142 HGEITTLGRGGSDTTAVALAAALKAEKCDIYTDVTGVFTTDPRYVKSARKLASISYDEML 201
Query: 233 IAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTS 276
A G + +A E AK I + + GT+I +
Sbjct: 202 ELANLGAGVLHPRAVEFAKNYGITLEVRSSMEREEGTIIEEEVT 245
>sp|Q9ZCI7|AK_RICPR ASPARTOKINASE (ASPARTATE KINASE) >gi|7434558|pir||E71635
aspartokinase (lysC) RP753 - Rickettsia prowazekii
>gi|3861282|emb|CAA15181.1| (AJ235273) ASPARTOKINASE
(lysC) [Rickettsia prowazekii]
Length = 446
Score = 88.9 bits (217), Expect = 8e-17
Identities = 82/269 (30%), Positives = 124/269 (45%), Gaps = 57/269 (21%)
Query: 4 MIVLKFGGSSVKN--DFHEAVSLTKS-IFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
+I+ KFGG+SV N + V + K+ I + +V VVVSA+ G+T+ L+ S
Sbjct: 3 LIIQKFGGTSVANVERIKKLVPIIKAEIAKNNQVIVVVSAMAGVTNQLVTLCNEVSS--- 59
Query: 61 IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFA---- 116
+ +FA D LS GE+++A + A
Sbjct: 60 ---LNKRSQFAEY---------------------------DVALSSGEIVTASLLALALQ 89
Query: 117 -EVVEGQVIYPWEL----FSAYGKFGDGFI--DLKKSKKNAKIIYEVIDSGKIPIVPGFV 169
E ++ Q + W+L + Y K FI DL + KII PI+ GF
Sbjct: 90 EEEIKAQSLLAWQLPIRTNNNYSKALVEFITTDLLEKYLQLKII---------PIIAGFQ 140
Query: 170 GGMDGYRVT-LGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSY 228
G RVT LGRGGSD +A + + ++ I ++V+GIFTADP+++P+A+ I + +
Sbjct: 141 GINKSNRVTTLGRGGSDTTAALIAAAMKADRCDIYTDVDGIFTADPRIIPNAKRIKEIDF 200
Query: 229 EEALIAAKHGMKAIQWKAAELAKEKKILM 257
E L A G K + +A EL KI M
Sbjct: 201 LEMLELASSGAKVLHPRAVELVMRYKIDM 229
>pir||H82086 aspartokinase I/homoserine dehydrogenase, threonine-sensitive
VC2364 [imported] - Vibrio cholerae (group O1 strain
N16961) >gi|9656933|gb|AAF95507.1| (AE004306)
aspartokinase I/homoserine dehydrogenase,
threonine-sensitive [Vibrio cholerae]
Length = 825
Score = 88.5 bits (216), Expect = 1e-16
Identities = 87/324 (26%), Positives = 151/324 (45%), Gaps = 39/324 (12%)
Query: 4 MIVLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSK--- 58
M VLKFGGSS+ + F A + + +++EVAVV+SA T+ L+ ++ +
Sbjct: 7 MRVLKFGGSSLADPERFLRAADIIANNAQQEEVAVVLSAPGKTTNKLVAVIESALRQGEV 66
Query: 59 --YAIKIADSYVKFARTNGVD---PNILSPHIQELFNPP--------------SLPKDAL 99
+++ S+ +A +G+ PN+ Q+ + + D +
Sbjct: 67 EAQIVELESSF--YALLDGIKAQLPNLDDSAYQQQVHSSMTQLRQFVHGITLLGMCPDNV 124
Query: 100 TDYILSIGE-----LLSAVIFAEVVEGQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIY 154
I+S GE L+ AV+ A+ + ++ P + A G + +D++ S + +
Sbjct: 125 NARIISKGERVSIQLMKAVMEAKGLPANLVDPVKYLLAKGDHLEAMVDVEISTQRFR--Q 182
Query: 155 EVIDSGKIPIVPGFVGG-MDGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTAD 213
+ + I+PGF G G V LGR GSDYSA L L ++ I ++V+G++ D
Sbjct: 183 APLPQQHVNIMPGFTAGNAQGELVCLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYNCD 242
Query: 214 PKLVPSARLIPYLSYEEALIAAKHGMKAIQWKA-AELAKEKKILMLFGRTNNWRMGTVIS 272
P+LV ARL+ LSY+EA+ + G + K A +A+ + ++ N GT+I
Sbjct: 243 PRLVDDARLLKSLSYQEAMELSYFGASVLHPKTIAPIAQFQIPCLIKNSFNPQGAGTLIG 302
Query: 273 NRTSRMPL----MTYKDGLLLINV 292
T L +T L ++NV
Sbjct: 303 QDTGEDKLAIKGITTLSNLTMVNV 326
>pir||T35383 probable aspartokinase - Streptomyces coelicolor
>gi|5123890|emb|CAB45482.1| (AL079348) putative
aspartokinase [Streptomyces coelicolor A3(2)]
Length = 425
Score = 88.5 bits (216), Expect = 1e-16
Identities = 83/283 (29%), Positives = 127/283 (44%), Gaps = 55/283 (19%)
Query: 4 MIVLKFGGSSVKNDFHEAVSLTKSIFEEK----EVAVVVSALKGITDMLIKYAKTFDSKY 59
++V K+GGSSV D + K I E K +V VVSA+ TD LI A+
Sbjct: 3 LVVQKYGGSSVA-DAEGIKRVAKRIVEAKKNGNQVVAVVSAMGDTTDELIDLAEQ----- 56
Query: 60 AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVV 119
+SP +P D +L+ GE +S + A +
Sbjct: 57 ---------------------VSP----------IPAGRELDMLLTAGERISMALLAMAI 85
Query: 120 EGQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEV-------IDSGKIPIVPGFVGGM 172
+ E S G D +K A+II +D G + IV GF G
Sbjct: 86 KN---LGHEAQSFTGSQAGVITDSVHNK--ARIIDVTPGRIRTSVDEGNVAIVAGFQGVS 140
Query: 173 DGYR--VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEE 230
+ TLGRGGSD +AVAL L++++ I ++V+G+FTADP++VP A+ I ++S+E+
Sbjct: 141 QDSKDITTLGRGGSDTTAVALAAALDADVCEIYTDVDGVFTADPRVVPKAKKIDWISFED 200
Query: 231 ALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISN 273
L A G K + + E A+ I + + + GT +S+
Sbjct: 201 MLELAASGSKVLLHRCVEYARRYNIPIHVRSSFSGLQGTWVSS 243
>sp|O67221|AK_AQUAE ASPARTOKINASE (ASPARTATE KINASE) >gi|7434554|pir||B70399
aspartokinase - Aquifex aeolicus
>gi|2983613|gb|AAC07182.1| (AE000726) aspartokinase
[Aquifex aeolicus]
Length = 415
Score = 88.5 bits (216), Expect = 1e-16
Identities = 84/280 (30%), Positives = 130/280 (46%), Gaps = 53/280 (18%)
Query: 3 KMIVLKFGGSSVKNDFHEAVSLT-----KSIFEEKEVAVVVSALKGITDMLIKYAKTFDS 57
K++V KFGG+SV E + L K++ + + VV SA+ G TD LI+ AK
Sbjct: 2 KILVQKFGGTSVGT--LERIELCAKRVIKALEKGYKPVVVSSAMAGETDSLIELAKKVHP 59
Query: 58 KYAIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAE 117
+ P + D +L++GE + +FA
Sbjct: 60 R------------------------------------PPEREMDTLLAVGEQKAIALFAM 83
Query: 118 VVEGQVIYPWELFSAYGKFGDGFIDLKKSKKNAKII-----YEVIDSGKIPIVPGFVGGM 172
+ ++ YP S G D +K + I +I+ G IP+V GF G
Sbjct: 84 TLN-KLGYP--AVSLCGWQVPIITDNVHTKARIRKIGISRLLSLIEEGYIPVVAGFQGVT 140
Query: 173 DGYRVT-LGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEA 231
+ + +T LGRGGSD +AVAL L ++ I ++V G+FTADP++VP+A+ I +SYEE
Sbjct: 141 EDWEITTLGRGGSDTTAVALAAALKADC-EINTDVPGVFTADPRIVPNAKKIKKISYEEM 199
Query: 232 LIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVI 271
L A G K +Q ++ E A + + + T + GT I
Sbjct: 200 LELASLGAKVMQIRSVEFAAKYNVRIHVRSTFSEEEGTWI 239
>gb|AAD41796.1| (AF135862) precursor monofunctional aspartokinase [Glycine max]
Length = 564
Score = 88.5 bits (216), Expect = 1e-16
Identities = 80/280 (28%), Positives = 134/280 (47%), Gaps = 35/280 (12%)
Query: 6 VLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYAIKI 63
V+KFGGSSV + E +L S EE+ + VV+SA+ T+ L+ + S I +
Sbjct: 87 VMKFGGSSVASADRMKEVATLILSFPEERPI-VVLSAMGKTTNKLLLAGEKAVSCGVINV 145
Query: 64 A---------DSYVKFARTNGVDPNILSPHIQEL---FNPPSLPKDALT---DYILSIGE 108
+ D +++ GVD +++S H++EL ++ K+ DY++S GE
Sbjct: 146 SSIEELCFIKDLHLRTVDQLGVDGSVISKHLEELEQLLKGIAMMKELTKRTQDYLVSFGE 205
Query: 109 LLSAVIFAEVVEGQVIYPWELFSAYGKFGDGFI--------DLKKSKKNA---KIIYEVI 157
+S IFA + + + Y F GFI D+ ++ A ++ + +
Sbjct: 206 CMSTRIFAAYLNKIGVKARQ----YDAFEIGFITTDDFTNADILEATYPAVAKRLHGDWL 261
Query: 158 DSGKIPIVPGFVGGM--DGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPK 215
I IV GF+G TLGRGGSD +A +G L + + +V+G+ T DP
Sbjct: 262 SDPAIAIVTGFLGKARKSCAVTTLGRGGSDLTATTIGKALGLPEIQVWKDVDGVLTCDPN 321
Query: 216 LVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKI 255
+ P A +PYL+++EA A G + + ++ A+E I
Sbjct: 322 IYPKAEPVPYLTFDEAAELAYFGAQVLHPQSMRPARESDI 361
>emb|CAA99580.1| (Z75208) aspartokinase II alpha subunit [Bacillus subtilis]
>gi|2635312|emb|CAB14807.1| (Z99118) aspartokinase II
alpha subunit (aa 1->408) and beta subunit (aa 246->408)
[Bacillus subtilis]
Length = 408
Score = 88.2 bits (215), Expect = 1e-16
Identities = 80/277 (28%), Positives = 128/277 (45%), Gaps = 38/277 (13%)
Query: 4 MIVLKFGGSSVKNDFHEAVSLTKSIFEEK---EVAVVVSALKGITDMLIKYAKTFDSKYA 60
+IV KFGG+SV + + ++I E++ +V VVVSA+ TD L+ AK + +
Sbjct: 3 LIVQKFGGTSVGSVEKIQNAANRAIAEKQKGHQVVVVVSAMGKSTDELVSLAKAISDQPS 62
Query: 61 IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
+ D + A V ++LS +QE D + G A I E +
Sbjct: 63 KREMDMLL--ATGEQVTISLLSMALQEKGY----------DAVSYTG--WQAGIRTEAIH 108
Query: 121 GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMDGYRVT-L 179
G + + + ++ + ++ GKI IV GF G + +T L
Sbjct: 109 GNA--------------------RITDIDTSVLADQLEKGKIVIVAGFQGMTEDCEITTL 148
Query: 180 GRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAKHGM 239
GRGGSD +AVAL L ++ I ++V G+FT DP+ V SAR + +SY+E L A G
Sbjct: 149 GRGGSDTTAVALAAALKADKCDIYTDVPGVFTTDPRYVKSARKLEGISYDEMLELANLGA 208
Query: 240 KAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTS 276
+ +A E AK ++ + + GT+I +S
Sbjct: 209 GVLHPRAVEFAKNYQVPLEVRSSTETEAGTLIEEESS 245
>pir||F82328 aspartokinase III, lysine-sensitive VC0391 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9654811|gb|AAF93564.1| (AE004127) aspartokinase III,
lysine-sensitive [Vibrio cholerae]
Length = 479
Score = 87.8 bits (214), Expect = 2e-16
Identities = 75/259 (28%), Positives = 127/259 (48%), Gaps = 26/259 (10%)
Query: 6 VLKFGGSSVKNDFHEAVSLTKSIFEEKEVA--VVVSALKGITDMLIKYAK---TFDSKYA 60
V KFGG+SV N EA+S +I E VV SA G+T++L++ A + + + A
Sbjct: 34 VAKFGGTSVAN--FEAMSRCSAIIENNPQTRLVVSSACSGVTNLLVELANGVASTERRQA 91
Query: 61 I--KIAD-SYVKFARTNGVDPNILSPHIQELFNPPSLPKDA--------LTDYILSIGEL 109
I ++AD YV + DP + ++ + + + +A LTD++++ GEL
Sbjct: 92 ILQQLADIHYVIIDQL--ADPTRVEKEVKAVLDSVASAAEAASFQSSKKLTDHLVACGEL 149
Query: 110 LSAVIFAEVVEGQVIYPW-----ELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPI 164
+S I +++ + + E+ +G LK+ + AK + + +
Sbjct: 150 ISTYILTQLMRERGVDAVRFDIREVLRTDDHYGRAEPQLKEIAQLAKEKLVPLCEQYVVV 209
Query: 165 VPGFVGG-MDGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLI 223
GF+G G TLGRGGSDYSA + + + + I ++V GI++ DP++ P A I
Sbjct: 210 TQGFIGSDAQGNTTTLGRGGSDYSAALIAEAVQASGLEIWTDVPGIYSTDPRIAPKAAPI 269
Query: 224 PYLSYEEALIAAKHGMKAI 242
P +S+ EA A G K +
Sbjct: 270 PEISFSEASEMANFGAKIL 288
>pir||B69207 aspartokinase II alpha subunit - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621892|gb|AAB85302.1| (AE000858) aspartokinase II
alpha subunit [Methanobacterium thermoautotrophicum]
Length = 406
Score = 87.4 bits (213), Expect = 2e-16
Identities = 69/253 (27%), Positives = 122/253 (47%), Gaps = 49/253 (19%)
Query: 3 KMIVLKFGGSSVKNDFH---EAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKY 59
++IV KFGG+S+ N A S+ K + ++V VVVSA+ TD L++
Sbjct: 2 ELIVAKFGGTSIGNGRRIKKAARSVVKEYMKGRKVVVVVSAINKTTDELLQ--------- 52
Query: 60 AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVV 119
I+ +++ L + I+S+GE+ S IF+ +
Sbjct: 53 --------------------IVDEAMEDAVTEKQLAE------IVSMGEMTSVRIFSSAI 86
Query: 120 EG-----QVIYP----WELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVG 170
E + I P W + + + +D + +++ ++ + +++D G IP+V GF+G
Sbjct: 87 EALGVKSEYIDPFMDEWPIITDSNLL-NAKVDFEATEEKSRELLKLLDQGIIPVVCGFLG 145
Query: 171 -GMDGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYE 229
+GY TLGRGGSD +A LG L ++ V I+++V G+ + DP + A+ + +S E
Sbjct: 146 RDPNGYITTLGRGGSDITAFLLGHCLKADEVIIVTDVGGVMSTDPNKLQGAKKLDKISVE 205
Query: 230 EALIAAKHGMKAI 242
E A HG + +
Sbjct: 206 EMRDLATHGAQVL 218
>pir||T48575 aspartate kinase - Arabidopsis thaliana >gi|7529283|emb|CAB86635.1|
(AL163491) aspartate kinase [Arabidopsis thaliana]
Length = 569
Score = 87.4 bits (213), Expect = 2e-16
Identities = 80/293 (27%), Positives = 140/293 (47%), Gaps = 26/293 (8%)
Query: 6 VLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYAIK- 62
V+KFGGSSV + E L + EE V V+ + K ++L+ K +
Sbjct: 89 VMKFGGSSVASAERMKEVADLILTFPEESPVIVLSAMGKTTNNLLLAGEKAVSCGVSNAS 148
Query: 63 -------IADSYVKFARTNGVDPNILSPHIQEL---FNPPSLPKDALT---DYILSIGEL 109
I + +++ + +DP+++ +++EL ++ K+ DY++S GE
Sbjct: 149 EIEELSIIKELHIRTVKELNIDPSVILTYLEELEQLLKGIAMMKELTLRTRDYLVSFGEC 208
Query: 110 LSAVIFAEV-----VEGQVIYPWEL-FSAYGKFGDGFIDLKKSKKNAKIIYEV-IDSGKI 162
LS IFA V+ + +E+ F F +G I AK +Y+ + +
Sbjct: 209 LSTRIFAAYLNTIGVKARQYDAFEIGFITTDDFTNGDILEATYPAVAKRLYDDWMHDPAV 268
Query: 163 PIVPGFVGG--MDGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSA 220
PIV GF+G G TLGRGGSD +A +G L + + + +V+G+ T DP + A
Sbjct: 269 PIVTGFLGKGWKTGAVTTLGRGGSDLTATTIGKALGLKEIQVWKDVDGVLTCDPTIYKRA 328
Query: 221 RLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRM-GTVIS 272
+PYL+++EA A G + + ++ A+E +I + + N + GT+I+
Sbjct: 329 TPVPYLTFDEAAELAYFGAQVLHPQSMRPAREGEIPVRVKNSYNPKAPGTIIT 381
>dbj|BAB08285.1| (AB007650) lysine-sensitive aspartate kinase [Arabidopsis thaliana]
Length = 544
Score = 87.4 bits (213), Expect = 2e-16
Identities = 77/296 (26%), Positives = 143/296 (48%), Gaps = 32/296 (10%)
Query: 6 VLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAK--------TF 55
V+KFGGSSV++ E +L S +E+ V +V+SA+ T+ L+K +
Sbjct: 85 VMKFGGSSVESAERMKEVANLILSFPDERPV-IVLSAMGKTTNKLLKAGEKAVTCGVTNV 143
Query: 56 DSKYAIK-IADSYVKFARTNGVDPNILSPHIQ---ELFNPPSLPKDALT---DYILSIGE 108
+S + I + +++ A GV+ ++ H++ +L S+ K+ DY++S GE
Sbjct: 144 ESIEELSFIKELHLRTAHELGVETTVIEKHLEGLHQLLKGISMMKELTLRTRDYLVSFGE 203
Query: 109 LLSAVIFAEVVE--GQVIYPWELFSAYGKFGDGF-----IDLKKSKKNAKIIYEVIDSGK 161
+S +F+ + G ++ F D F ++ + ++ +
Sbjct: 204 CMSTRLFSAYLNKIGHKARQYDAFEIGFITTDDFTNADILEATYPAVSKTLVGDWSKENA 263
Query: 162 IPIVPGFVGGMDGYR----VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLV 217
+P+V G++G G+R TLGRGGSD +A +G L + + +V+G+ T DP +
Sbjct: 264 VPVVTGYLG--KGWRSCAITTLGRGGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIY 321
Query: 218 PSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKI-LMLFGRTNNWRMGTVIS 272
P A+ +PYL+++EA A G + + + A++ I + + N GTVI+
Sbjct: 322 PGAQSVPYLTFDEAAELAYFGAQVLHPLSMRPARDGDIPVRVKNSYNPTAPGTVIT 377
>pir||H81865 aspartate kinase (EC 2.7.2.4) NMA1701 [imported] - Neisseria
meningitidis (group A strain Z2491)
>gi|7380342|emb|CAB84929.1| (AL162756) aspartate kinase
[Neisseria meningitidis Z2491]
Length = 405
Score = 87.4 bits (213), Expect = 2e-16
Identities = 81/283 (28%), Positives = 136/283 (47%), Gaps = 57/283 (20%)
Query: 4 MIVLKFGGSSVKNDF---HEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
+IV K+GG+SV + + A + K+ E ++ VVVSA+ G T+ L+
Sbjct: 3 LIVHKYGGTSVGSPERIKNVAKRVAKARAEGHDIVVVVSAMSGETNRLVA---------- 52
Query: 61 IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEV-- 118
L+ +QE +P L D +LS GE ++ + A
Sbjct: 53 --------------------LAHEMQEHPDPREL------DVVLSTGEQVTIGLLAMALK 86
Query: 119 ---VEGQVIYPWELF----SAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVG- 170
V+ + W++ +A+ K ID +K + + + +GK+ IV GF G
Sbjct: 87 DIGVDAKSYTGWQVALKTDTAHTKARIESIDDEKMRAD-------LTAGKVVIVAGFQGI 139
Query: 171 GMDGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEE 230
+G TLGRGGSD SAVAL L ++ I ++V+G++T DP++VP AR + +++EE
Sbjct: 140 SSEGDISTLGRGGSDTSAVALAAALKADECQIYTDVDGVYTTDPRVVPEARRMDTVTFEE 199
Query: 231 ALIAAKHGMKAIQWKAAELAKEKKI-LMLFGRTNNWRMGTVIS 272
+ A G K +Q ++ E A + K+ L + + GT+I+
Sbjct: 200 MIELASLGSKVLQIRSVEFAGKYKVRLRVLSSLQDGGNGTLIT 242
>sp|P77991|AK_THEFL ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: ASPARTOKINASE ALPHA
SUBUNIT (ASK-ALPHA); ASPARTOKINASE BETA SUBUNIT
(ASK-BETA)] >gi|1616997|dbj|BAA07146.1| (D37928)
aspartokinase alpha-2 [Thermus aquaticus]
Length = 405
Score = 87.4 bits (213), Expect = 2e-16
Identities = 75/282 (26%), Positives = 127/282 (44%), Gaps = 44/282 (15%)
Query: 4 MIVLKFGGSSVKNDFHEAVSLTKSIFEEKE----VAVVVSALKGITDMLIKYAKTFDSKY 59
++V K+GG+SV D + + I +E +AVVVSA+ TD LI AK + +
Sbjct: 3 LVVQKYGGTSV-GDLERIHKVAQRIAHYREKGHRLAVVVSAMGHTTDELIALAKRVNPR- 60
Query: 60 AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIG-ELLSAVIFAEV 118
PP D LT + LLS ++A
Sbjct: 61 -------------------------------PPFRELDLLTTTGEQVSVALLSMQLWAMG 89
Query: 119 VEGQVIYPWEL-FSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGM-DGYR 176
+ + ++ + G++GD I + N I E +D G + ++ GF+G +G
Sbjct: 90 IPAKGFVQHQIGITTDGRYGDARI----LEVNPARIREALDQGFVAVIAGFMGTTPEGEI 145
Query: 177 VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAK 236
TLGRGGSD +AVA+ L ++ I ++ EG++T DP L+P AR + + Y++ L A
Sbjct: 146 TTLGRGGSDTTAVAIAAALGAKECEIYTDTEGVYTTDPHLIPEARKLSVIGYDQMLEMAA 205
Query: 237 HGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRM 278
G + + +A AK +++ + ++ GT++ M
Sbjct: 206 LGARVLHPRAVYYAKRYGVVLHVRSSFSYNPGTLVKEVAMEM 247
>emb|CAA67376.1| (X98873) aspartate kinase [Arabidopsis thaliana]
Length = 569
Score = 87.0 bits (212), Expect = 3e-16
Identities = 80/293 (27%), Positives = 140/293 (47%), Gaps = 26/293 (8%)
Query: 6 VLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYAIK- 62
V+KFGGSSV + E L + EE V V+ + K ++L+ K +
Sbjct: 89 VMKFGGSSVASAERMKEVADLILTFPEESPVIVLSAMGKTTNNLLLAGEKAVSCGVSNAS 148
Query: 63 -------IADSYVKFARTNGVDPNILSPHIQEL---FNPPSLPKDALT---DYILSIGEL 109
I + +++ + +DP+++ +++EL ++ K+ DY++S GE
Sbjct: 149 EIEELSIIKELHIRTVKELNIDPSVILTYLEELEQLLKGIAMMKELTLRTRDYLVSFGEC 208
Query: 110 LSAVIFAEV-----VEGQVIYPWEL-FSAYGKFGDGFIDLKKSKKNAKIIYEV-IDSGKI 162
LS IFA V+ + +E+ F F +G I AK +Y+ + +
Sbjct: 209 LSTRIFAAYLNTIGVKARQYDAFEIGFITTDDFTNGDILEATYPAVAKRLYDDWMHDPAV 268
Query: 163 PIVPGFVGG--MDGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSA 220
PIV GF+G G TLGRGGSD +A +G L + + + +V+G+ T DP + A
Sbjct: 269 PIVTGFLGKGWKTGAVTTLGRGGSDLTATTIGKALGLKEIQVWKDVDGVLTCDPTIYKRA 328
Query: 221 RLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRM-GTVIS 272
+PYL+++EA A G + + ++ A+E +I + + N + GT+I+
Sbjct: 329 TPVPYLTFDEAAELAYFGAQVLHPQSMRPAREGEIPVRVKSSYNPKAPGTIIT 381
>sp|P08495|AK2_BACSU ASPARTOKINASE 2 (ASPARTOKINASE II) (ASPARTATE KINASE 2) [CONTAINS:
ASPARTOKINASE II ALPHA SUBUNIT; ASPARTOKINASE II BETA
SUBUNIT] >gi|80248|pir||A29314 aspartate kinase (EC
2.7.2.4) II precursor - Bacillus subtilis
>gi|142523|gb|AAA87318.1| (J03294) aspartokinase II
alpha subunit [Bacillus subtilis]
Length = 408
Score = 87.0 bits (212), Expect = 3e-16
Identities = 80/277 (28%), Positives = 127/277 (44%), Gaps = 38/277 (13%)
Query: 4 MIVLKFGGSSVKNDFHEAVSLTKSIFEEK---EVAVVVSALKGITDMLIKYAKTFDSKYA 60
+IV KFGG+SV + + ++I E++ +V VVVSA+ TD L+ AK + +
Sbjct: 3 LIVQKFGGTSVGSVEKIQNAANRAIAEKQKGHQVVVVVSAMGKSTDELVSLAKAISDQPS 62
Query: 61 IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
+ D + A V ++LS +QE D + G A I E +
Sbjct: 63 KREMDMLL--ATGEQVTISLLSMALQEKGY----------DAVSYTG--WQAGIRTEAIH 108
Query: 121 GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMDGYRVT-L 179
G + + + ++ + ++ GKI IV GF G + +T L
Sbjct: 109 GNA--------------------RITDIDTSVLADQLEKGKIVIVAGFQGMTEDCEITTL 148
Query: 180 GRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAKHGM 239
GRGGSD +AVAL L + I ++V G+FT DP+ V SAR + +SY+E L A G
Sbjct: 149 GRGGSDTTAVALAAALKVDKCDIYTDVPGVFTTDPRYVKSARKLEGISYDEMLELANLGA 208
Query: 240 KAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTS 276
+ +A E AK ++ + + GT+I +S
Sbjct: 209 GVLHPRAVEFAKNYQVPLEVRSSTETEAGTLIEEESS 245
>pir||A82311 aspartokinase, alpha and beta chains VC0547 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9654975|gb|AAF93715.1| (AE004140) aspartokinase,
alpha and beta subunits [Vibrio cholerae]
Length = 395
Score = 86.2 bits (210), Expect = 5e-16
Identities = 85/303 (28%), Positives = 133/303 (43%), Gaps = 46/303 (15%)
Query: 2 RKMIVLKFGGSSVKNDFHEAVSLTKSIFEEK----EVAVVVSALKGITDMLIKYAKTFDS 57
+ +IV KFGG+SV ++ + I + K +V VVVSA+ G T+ L+ A+ DS
Sbjct: 3 KPLIVQKFGGTSV-GSIERMQTVAEHIIKAKNDGNQVVVVVSAMAGETNRLVGLAQQVDS 61
Query: 58 KYAIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAE 117
P+ +EL D +LS GE +S + A
Sbjct: 62 V------------------------PNAREL------------DVLLSAGEQVSMALVAM 85
Query: 118 VVEGQVIYPWELFSAYGKF--GDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVG-GMDG 174
+ L A + D + + I E+++ I IV GF G +G
Sbjct: 86 TLHKMGYAARSLTGAQANIVTDNQHNDATIKHIDTRTITELLEQDFIVIVAGFQGINENG 145
Query: 175 YRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIA 234
TLGRGGSD SAVAL LN++ I ++V+GI+T DP++VPSAR + + +
Sbjct: 146 DITTLGRGGSDTSAVALAGALNADECQIFTDVDGIYTCDPRIVPSARKLDVIDFPSMEEM 205
Query: 235 AKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVI--SNRTSRMPLMTYKDGLLLINV 292
A+ G K + + A + + + T G++I S T + + + + LI V
Sbjct: 206 ARKGAKVLHLPCVQYAWKHAVPLRVLSTFEVNQGSLIKGSAATHAVCGIALQRDMALIRV 265
Query: 293 EEE 295
E E
Sbjct: 266 ESE 268
>pir||F81076 aspartokinase, alpha and beta chains NMB1498 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7226740|gb|AAF41854.1| (AE002499) aspartokinase,
alpha and beta subunits [Neisseria meningitidis MC58]
Length = 405
Score = 86.2 bits (210), Expect = 5e-16
Identities = 80/278 (28%), Positives = 135/278 (47%), Gaps = 47/278 (16%)
Query: 4 MIVLKFGGSSVKNDF---HEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
+IV K+GG+SV + + A + K+ E ++ VVVSA+ G T+ L+
Sbjct: 3 LIVHKYGGTSVGSPERIKNVAKRVAKARAEGHDIVVVVSAMSGETNRLVA---------- 52
Query: 61 IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
L+ +QE +P L T ++IG LL+ + V+
Sbjct: 53 --------------------LAHEMQEHPDPRELDVVLATGEQVTIG-LLAMALKDIGVD 91
Query: 121 GQVIYPWELF----SAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVG-GMDGY 175
+ W++ +A+ K ID +K + + + +GK+ IV GF G +G
Sbjct: 92 AKSYTGWQVALKTDTAHTKARIESIDDEKMRAD-------LTAGKVVIVAGFQGISSEGD 144
Query: 176 RVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAA 235
TLGRGGSD SAVAL L ++ I ++V+G++T DP++VP AR + +++EE + A
Sbjct: 145 ISTLGRGGSDTSAVALAAALKADECQIYTDVDGVYTTDPRVVPEARRMDTVTFEEMIELA 204
Query: 236 KHGMKAIQWKAAELAKEKKI-LMLFGRTNNWRMGTVIS 272
G K +Q ++ E A + K+ L + + GT+I+
Sbjct: 205 SLGSKVLQIRSVEFAGKYKVRLRVLSSLQDGGNGTLIT 242
>sp|P97151|AK_THETH ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: ASPARTOKINASE ALPHA
SUBUNIT (ASK-ALPHA); ASPARTOKINASE BETA SUBUNIT
(ASK-BETA)] >gi|3088363|dbj|BAA25848.1| (AB013131)
aspartate kinase alpha subunit [Thermus thermophilus]
Length = 405
Score = 85.8 bits (209), Expect = 7e-16
Identities = 74/282 (26%), Positives = 127/282 (44%), Gaps = 44/282 (15%)
Query: 4 MIVLKFGGSSVKNDFHEAVSLTKSIFEEKE----VAVVVSALKGITDMLIKYAKTFDSKY 59
++V K+GG+SV D + + I +E +AVVVSA+ TD LI AK + +
Sbjct: 3 LVVQKYGGTSV-GDLERIHKVAQRIAHYREKGHRLAVVVSAMGHTTDELIALAKRVNPR- 60
Query: 60 AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIG-ELLSAVIFAEV 118
PP D LT + LLS ++A
Sbjct: 61 -------------------------------PPFRELDLLTTTGEQVSVALLSMQLWAMG 89
Query: 119 VEGQVIYPWEL-FSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGM-DGYR 176
+ + ++ + G++GD I + N I E ++ G + ++ GF+G +G
Sbjct: 90 IPAKGFVQHQIGITTDGRYGDARI----LEVNPARIREALEQGFVAVIAGFMGTTPEGEI 145
Query: 177 VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAK 236
TLGRGGSD +AVA+ L ++ I ++ EG++T DP L+P AR + + Y++ L A
Sbjct: 146 TTLGRGGSDTTAVAIAAALGAKECEIYTDTEGVYTTDPHLIPEARKLSVIGYDQMLEMAA 205
Query: 237 HGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRM 278
G + + +A AK +++ + ++ GT++ M
Sbjct: 206 LGARVLHPRAVYYAKRYGVVLHVRSSFSYNPGTLVKEVAMEM 247
>gb|AAB49995.1| (U90239) aspartokinase [Mycobacterium tuberculosis]
Length = 428
Score = 85.0 bits (207), Expect = 1e-15
Identities = 91/326 (27%), Positives = 146/326 (43%), Gaps = 66/326 (20%)
Query: 4 MIVLKFGGSSVKNDFH-----EAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSK 58
++V K+GGSSV + E + TK + +V VVVSA+ TD L+ A+
Sbjct: 3 LVVQKYGGSSVADAERIRRVAERIVATKK--QGNDVVVVVSAMGDTTDDLLDLAQQ---- 56
Query: 59 YAIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEV 118
V P +P +EL D +L+ GE +S + A
Sbjct: 57 -----------------VCP---APPPREL------------DMLLTAGERISNALVAMA 84
Query: 119 VEGQVIYPWELF-SAYGKFGDGFIDLKKSKKNAKII-------YEVIDSGKIPIVPGFVG 170
+E + S G G + NAKII ++ G++ +V GF G
Sbjct: 85 IESLGAHARSFTGSQAGVITTG------THGNAKIIDVTPGRLQTALEEGRVVLVAGFQG 138
Query: 171 GMDGYR--VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSY 228
+ TLGRGGSD +AVA+ L +++ I ++V+GIF+ADP++V +AR + +++
Sbjct: 139 VSQDTKDVTTLGRGGSDTTAVAMAAALGADVCEIYTDVDGIFSADPRIVRNARKLDTVTF 198
Query: 229 EEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDGLL 288
EE L A G K + + E A+ I + + + R GTV+ +P+ +D +L
Sbjct: 199 EEMLEMAACGAKVLMLRCVEYARRHNIPVHVRSSYSDRPGTVVVGSIKDVPM---EDPIL 255
Query: 289 LINVEEELEYRVIDEGPFWKLYDVPG 314
+ E +V G L D+PG
Sbjct: 256 TGVAHDRSEAKVTIVG----LPDIPG 277
>sp|P97048|AK_MYCTU ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: ASPARTOKINASE ALPHA
SUBUNIT (ASK-ALPHA); ASPARTOKINASE BETA SUBUNIT
(ASK-BETA)] >gi|7434559|pir||F70794 probable ask protein
- Mycobacterium tuberculosis (strain H37RV)
>gi|2960133|emb|CAA18031.1| (AL022121) ask
[Mycobacterium tuberculosis]
Length = 421
Score = 85.0 bits (207), Expect = 1e-15
Identities = 91/326 (27%), Positives = 146/326 (43%), Gaps = 66/326 (20%)
Query: 4 MIVLKFGGSSVKNDFH-----EAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSK 58
++V K+GGSSV + E + TK + +V VVVSA+ TD L+ A+
Sbjct: 3 LVVQKYGGSSVADAERIRRVAERIVATKK--QGNDVVVVVSAMGDTTDDLLDLAQQ---- 56
Query: 59 YAIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEV 118
V P +P +EL D +L+ GE +S + A
Sbjct: 57 -----------------VCP---APPPREL------------DMLLTAGERISNALVAMA 84
Query: 119 VEGQVIYPWELF-SAYGKFGDGFIDLKKSKKNAKII-------YEVIDSGKIPIVPGFVG 170
+E + S G G + NAKII ++ G++ +V GF G
Sbjct: 85 IESLGAHARSFTGSQAGVITTG------THGNAKIIDVTPGRLQTALEEGRVVLVAGFQG 138
Query: 171 GMDGYR--VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSY 228
+ TLGRGGSD +AVA+ L +++ I ++V+GIF+ADP++V +AR + +++
Sbjct: 139 VSQDTKDVTTLGRGGSDTTAVAMAAALGADVCEIYTDVDGIFSADPRIVRNARKLDTVTF 198
Query: 229 EEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDGLL 288
EE L A G K + + E A+ I + + + R GTV+ +P+ +D +L
Sbjct: 199 EEMLEMAACGAKVLMLRCVEYARRHNIPVHVRSSYSDRPGTVVVGSIKDVPM---EDPIL 255
Query: 289 LINVEEELEYRVIDEGPFWKLYDVPG 314
+ E +V G L D+PG
Sbjct: 256 TGVAHDRSEAKVTIVG----LPDIPG 277
>gb|AAK41163.1| Aspartokinase (akH) [Sulfolobus solfataricus]
Length = 446
Score = 84.7 bits (206), Expect = 2e-15
Identities = 82/271 (30%), Positives = 135/271 (49%), Gaps = 45/271 (16%)
Query: 5 IVLKFGGSSVKNDFHEAVSLTKSI--FEEK--EVAVVVSALKGITDMLIKYAKTFDS--- 57
+++K GGS ++ D + + K I F +K ++ VV SA+K +T+ LI D+
Sbjct: 3 LIVKIGGS-IQKDEKDYELIVKKIQDFSKKSDKIIVVTSAIKNVTNELISATSNTDNSPN 61
Query: 58 ----------KYAIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPK--DALT----D 101
K K+AD K + D + LS ELF + D +T D
Sbjct: 62 IVTEIYERHIKLLSKLADG--KEFENSFKDISRLS---DELFRVAWSIRVLDEVTPRVRD 116
Query: 102 YILSIGELLSAVIFAEVV-------EGQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIY 154
YILS GE ++ ++ + ++ EG + P+ YG+ + DL K++ I
Sbjct: 117 YILSFGERMATLLLSAILRSNGIEAEGIITPPFLTDENYGE-ANVIEDLSKNE-----IA 170
Query: 155 EVIDSGK--IPIVPGFVGGM-DGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFT 211
++++ K + ++PGF+G +G TLGRGGSDY+A LG ++ V +++ V GI T
Sbjct: 171 NILENAKANVIVLPGFIGRTREGRYTTLGRGGSDYTATLLGKLVGVREVRLVTEVPGIMT 230
Query: 212 ADPKLVPSARLIPYLSYEEALIAAKHGMKAI 242
DPK +A+ I LS EEA+ ++ G K +
Sbjct: 231 GDPKKFENAKTISRLSLEEAIELSQLGAKRL 261
>dbj|BAB06815.1| (AP001517) aspartokinase II alpha and beta subunits [Bacillus
halodurans]
Length = 412
Score = 84.7 bits (206), Expect = 2e-15
Identities = 77/279 (27%), Positives = 126/279 (44%), Gaps = 52/279 (18%)
Query: 4 MIVLKFGGSSV---KNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
+IV K+GG+SV + H A + + K+V VVVSA+ TD L+ A
Sbjct: 3 IIVQKYGGTSVGSVQRIEHVANRIIATAASGKKVVVVVSAMGKTTDELVGLAS------- 55
Query: 61 IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVV- 119
+I D P+ D +L+ GE ++ + A +
Sbjct: 56 -EITDE----------------------------PRKREMDMLLATGEQVTIALLAMALH 86
Query: 120 ----EGQVIYPWE--LFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVG-GM 172
E + W+ + + +++++++ + E++D + IV GF G
Sbjct: 87 KRGQEATSLTGWQAGMITESHHGNARILEVERARMD-----ELLDKVHVVIVAGFQGIDQ 141
Query: 173 DGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEAL 232
G +TLGRGGSD SAVA+ L +E I ++V G+FT DP++V AR + +SY+E L
Sbjct: 142 QGEIMTLGRGGSDTSAVAIAAALKAERCEIYTDVTGVFTTDPRVVKQARKLQTISYDEML 201
Query: 233 IAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVI 271
A G + +A E AK +I +L + GT+I
Sbjct: 202 EMANLGASVLHPRAVEFAKNYEIPLLVASSMVDEPGTMI 240
>pir||G72245 aspartokinase II - Thermotoga maritima (strain MSB8)
>gi|4982084|gb|AAD36585.1|AE001799_17 (AE001799)
aspartokinase II [Thermotoga maritima]
Length = 401
Score = 84.3 bits (205), Expect = 2e-15
Identities = 80/277 (28%), Positives = 124/277 (43%), Gaps = 43/277 (15%)
Query: 4 MIVLKFGGSSVKNDF---HEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
++V K+GGSSV + A + K + E +V VVVSA+ TD LIK AK +
Sbjct: 3 VVVQKYGGSSVATPERIKNVAQRIKKKVDEGYKVVVVVSAMGKTTDNLIKLAKEISPR-- 60
Query: 61 IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
P +EL D +L+ GE +SA + + ++
Sbjct: 61 ----------------------PDSREL------------DMLLATGEQVSAALLSMALK 86
Query: 121 GQVIYPWEL--FSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMD-GYRV 177
+ L F K + + +I E + + +V GF G + G
Sbjct: 87 DLGVKAKSLNAFQVKIKTTPHHTSARIVDIDDSVIRENLKDYDVLVVTGFQGVNEHGDLT 146
Query: 178 TLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAKH 237
TLGRGGSD SAVAL L I S+V+GI+T DP++ P A+ + Y++Y+EAL
Sbjct: 147 TLGRGGSDTSAVALAAKLRVPC-EIYSDVDGIYTCDPRVHPRAKKLAYITYDEALELTAL 205
Query: 238 GMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNR 274
G K + ++ E+AK+ I + + GT++ R
Sbjct: 206 GAKVLHSRSVEIAKKYGIPIYCASSFTEEEGTMVVER 242
>gb|AAF03452.1|AC010797_28 (AC010797) putative aspartate kinase [Arabidopsis thaliana]
>gi|6513929|gb|AAF14833.1|AC011664_15 (AC011664)
putative aspartate kinase [Arabidopsis thaliana]
Length = 559
Score = 83.9 bits (204), Expect = 3e-15
Identities = 77/298 (25%), Positives = 142/298 (46%), Gaps = 36/298 (12%)
Query: 6 VLKFGGSSVKNDFHEAVSLTKSI--FEEKEVAVVVSALKGITDMLIKYAK---------- 53
V+KFGGSSV + + + K I F +++ VV+SA+ T+ L+ +
Sbjct: 86 VMKFGGSSVASA-ERMIQVAKLILSFPDEKPVVVLSAMAKTTNKLLMAGEKAVCCGVTNV 144
Query: 54 -TFDSKYAIKIADSYVKFARTNGVDPNILSPHIQ---ELFNPPSLPKDALT---DYILSI 106
T + IK + +++ A GV+ +++ H++ +L ++ K+ DY++S
Sbjct: 145 DTIEELSYIK--ELHIRTAHELGVETAVIAEHLEGLEQLLKGVAMMKELTLRSRDYLVSF 202
Query: 107 GELLSAVIFAEVVE--GQVIYPWELFSAYGKFGDGF-----IDLKKSKKNAKIIYEVIDS 159
GE +S +FA + G ++ F D F ++ + K++ +
Sbjct: 203 GECMSTRLFAAYLNKIGHKARQYDAFEIGIITTDDFTNADILEATYPAVSKKLLGDWSKE 262
Query: 160 GKIPIVPGFVGGMDGYR----VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPK 215
+P+V GF+G G+R TLGRGGSD +A +G L + + +V+G+ T DP
Sbjct: 263 NALPVVTGFLG--KGWRSCAVTTLGRGGSDLTATTIGKALGLREIQVWKDVDGVLTCDPN 320
Query: 216 LVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKI-LMLFGRTNNWRMGTVIS 272
+ A+ +P+L+++EA A G + + + A+E I + + N GTVI+
Sbjct: 321 IYCGAQPVPHLTFDEAAELAYFGAQVLHPLSMRPAREGNIPVRVKNSYNPTAPGTVIT 378
>emb|CAC06395.1| (Y16255) aspartate kinase [Arabidopsis thaliana]
Length = 544
Score = 83.5 bits (203), Expect = 4e-15
Identities = 75/297 (25%), Positives = 139/297 (46%), Gaps = 34/297 (11%)
Query: 6 VLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDML----------IKYAK 53
V+KFGGSSV + E +L S +E+ V V+ + K I +L + +
Sbjct: 85 VMKFGGSSVGSAERMKEVANLIFSFPDERPVIVLSAMGKTINKLLKAGEKAVTCGVTNVE 144
Query: 54 TFDSKYAIKIADSYVKFARTNGVDPNILSPHIQ---ELFNPPSLPKDALT---DYILSIG 107
+ + IK + +++ A GV+ ++ H++ +L S+ K+ DY++S G
Sbjct: 145 SIEELSFIK--ELHLRTAHELGVETTVIEKHLEGLHQLLKGISMMKELTLRTRDYLVSFG 202
Query: 108 ELLSAVIFAEVVE--GQVIYPWELFSAYGKFGDGF-----IDLKKSKKNAKIIYEVIDSG 160
E +S +F+ + G ++ F D F ++ + ++ +
Sbjct: 203 ECMSTRLFSAYLNKIGHKARQYDAFEIGFITTDDFTNADILEATYPAVSKTLVGDWSKEN 262
Query: 161 KIPIVPGFVGGMDGYR----VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKL 216
+P+V G++G G+R TLGRGGSD +A +G L + + +V+G+ T DP +
Sbjct: 263 AVPVVTGYLG--KGWRSCAITTLGRGGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNI 320
Query: 217 VPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKI-LMLFGRTNNWRMGTVIS 272
P A+ +PYL+++EA A G + + + A++ I + + N GTVI+
Sbjct: 321 YPGAQSVPYLTFDEAAELAYFGAQVLHPLSMRPARDGDIPVRVKNSYNPTAPGTVIT 377
>gb|AAB63104.1| (U62020) lysine-sensitive aspartate kinase [Arabidopsis thaliana]
Length = 544
Score = 82.7 bits (201), Expect = 6e-15
Identities = 75/295 (25%), Positives = 136/295 (45%), Gaps = 30/295 (10%)
Query: 6 VLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDS------ 57
V+KFGGSSV + E +L S +E+ V V+ + K I +L K
Sbjct: 85 VMKFGGSSVGSAERMKEVANLIFSFPDERPVIVLSAMGKTINKLLKAGEKAVTCGVTNVG 144
Query: 58 --KYAIKIADSYVKFARTNGVDPNILSPHIQ---ELFNPPSLPKDALT---DYILSIGEL 109
+ I + +++ A GV+ ++ H++ +L S+ K+ DY++S GE
Sbjct: 145 SIEELSFIKELHLRTAHELGVETTVIEKHLEGLHQLLKGISMMKELTLRTRDYLVSFGEC 204
Query: 110 LSAVIFAEVVE--GQVIYPWELFSAYGKFGDGF-----IDLKKSKKNAKIIYEVIDSGKI 162
+S +F+ + G ++ F D F ++ + ++ + +
Sbjct: 205 MSTRLFSAYLNKIGHKARQYDAFEIGFITTDDFTNADILEATYPAVSKTLVGDWSKENAV 264
Query: 163 PIVPGFVGGMDGYR----VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVP 218
P+V G++G G+R TLGRGGSD +A +G L + + +V+G+ T DP + P
Sbjct: 265 PVVTGYLG--KGWRSCAITTLGRGGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIYP 322
Query: 219 SARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKI-LMLFGRTNNWRMGTVIS 272
A+ +PYL+++EA A G + + + A++ I + + N GTVI+
Sbjct: 323 GAQSVPYLTFDEAAELAYFGAQVLHPLSMRPARDGDIPVRVKNSYNPTAPGTVIT 377
>pir||D81681 aspartokinase III TC0641 [imported] - Chlamydia muridarum (strain
Nigg) >gi|7190680|gb|AAF39470.1| (AE002332)
aspartokinase III [Chlamydia muridarum]
Length = 437
Score = 82.3 bits (200), Expect = 8e-15
Identities = 71/247 (28%), Positives = 119/247 (47%), Gaps = 11/247 (4%)
Query: 5 IVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKT---FDSKYAI 61
+V KFGG+SV + + I +EK VVVSA+ G+TD+L ++ + S++
Sbjct: 9 LVCKFGGTSVGTS-SSIQRVCEIIRKEKPSFVVVSAVAGVTDLLEEFCRAPVGQKSQFTA 67
Query: 62 KIADSYVKFARTNGVDPNILSPHIQEL--FNPPSLPKDALTDYILSIGELLSAVIFAEVV 119
I + + A+ G+D I P + L F + IL+IGE LSA +
Sbjct: 68 MIREKHESIAKELGIDVAI-EPFLGPLKQFEGAGHLQQEDQAKILAIGEDLSASLICSYC 126
Query: 120 EGQVIYPWELFSAYGKFGDG-FIDLKKSKKNAKIIYE--VIDSGKIPIVPGFVGGM-DGY 175
+ +L + D F+ + + ++ V+ I ++ GF+G G
Sbjct: 127 RANSLQLEQLEARQVILTDSQFLRAEPDLALMQTMWGELVLKENTIYLMQGFLGATASGA 186
Query: 176 RVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAA 235
LGRGGSD+SA +G + + + I ++V G+ TADPK++ +LI +L++EE A
Sbjct: 187 TTVLGRGGSDFSASLVGELCEARELRIYTDVRGVHTADPKILKDTQLIDFLTFEEMQELA 246
Query: 236 KHGMKAI 242
G K +
Sbjct: 247 SSGSKVL 253
>emb|CAC11508.1| (AL445064) aspartate kinase related protein [Thermoplasma
acidophilum]
Length = 272
Score = 81.1 bits (197), Expect = 2e-14
Identities = 82/283 (28%), Positives = 125/283 (43%), Gaps = 23/283 (8%)
Query: 1 MRKMIVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
M + V+K GGS +K D + I + +VVSA GITD L ++ + +D
Sbjct: 1 MTEKCVIKIGGSVLK-DGSSLPRVMDIISHFRSPILVVSAFGGITDALYRFYE-YDESRM 58
Query: 61 IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDY--ILSIGELLSAVIFAEV 118
K+ D + IL + E S+ ++ D +S GE +SA A
Sbjct: 59 DKLRDLLLMHL-------GILWKYNIEAHPEISIQDSSILDQDAYVSYGEKMSAFTLARF 111
Query: 119 VEGQVIYPWELFSAYGKF------GDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGM 172
+ G I +++ + +DL+ S+ + I V SGK+P+V GF G +
Sbjct: 112 LTGNGIPAAPIYTDEAGLIVEEISKERTVDLEGSRAFFENIARVETSGKVPVVTGFFG-I 170
Query: 173 DGYRVT--LGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEE 230
D Y T LGR SDYSAVA+ IL V ++ +V GI+ L ++ + YE
Sbjct: 171 DRYGKTRILGRNSSDYSAVAVAAILGIREVILIKDVPGIYM---NLEDRTSIVNRIDYET 227
Query: 231 ALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISN 273
AL G K + A LA + + +L N GTVI +
Sbjct: 228 ALRIVDRGSKVVHRAALRLAMKMGMNLLITSPENLESGTVIGD 270
>pir||F75405 aspartate kinase - Deinococcus radiodurans (strain R1)
>gi|6459119|gb|AAF10936.1|AE001982_10 (AE001982)
aspartate kinase [Deinococcus radiodurans]
Length = 473
Score = 80.4 bits (195), Expect = 3e-14
Identities = 82/313 (26%), Positives = 143/313 (45%), Gaps = 43/313 (13%)
Query: 3 KMIVLKFGGSSVKNDF---HEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKY 59
+++V+KFGG+++++ H A +S+ E +V VVVSA+ G+T+ L+ A S
Sbjct: 9 RLLVMKFGGTNMQSAHAIRHSASLAGRSVREGVKVVVVVSAMAGVTNGLLHLADAAQSGD 68
Query: 60 AIKIADSYVKF-------ARTNGVDPNILSPHIQELFNPPSLPKDAL------------- 99
+ D A+ G P+ S ++EL + A+
Sbjct: 69 IARANDEIAALRTRHFTAAQELGAAPD--SETVRELRELHETLRQAVYGVYLLRELTPRS 126
Query: 100 TDYILSIGELLSAVIFAEVVEGQVIYPWELFSAYGKFGDGFIDLKKSKKNAKII---YE- 155
D I++ GE LSA + + +E + L G+ I + NA+ + YE
Sbjct: 127 RDLIVAFGERLSAPLMSLALEQSGLRARHLTG-----GEAGILTDTNFGNARPLPGTYER 181
Query: 156 -------VIDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVE 207
+ +G P++ GF+G + G TLGRGG+D+SA +G L ++ V +V+
Sbjct: 182 VGDRLSGFLSAGVTPVIAGFMGETEQGAITTLGRGGTDFSATIVGKALGADEVWAWKDVD 241
Query: 208 GIFTADPKLVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKI-LMLFGRTNNWR 266
G+ +ADP++V A I LSY E + A G K + A ++ I L + +
Sbjct: 242 GVMSADPRVVGDASNIGVLSYGEVMELAYFGAKVLHPLAVTPLQDSGIPLRVKSAADPDF 301
Query: 267 MGTVISNRTSRMP 279
GT++ ++ +P
Sbjct: 302 AGTLVRSQAEEIP 314
>emb|CAB57346.1| (Y15939) aspartokinase [Dichelobacter nodosus]
Length = 206
Score = 79.6 bits (193), Expect = 5e-14
Identities = 47/137 (34%), Positives = 79/137 (57%), Gaps = 2/137 (1%)
Query: 153 IYEVIDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFT 211
IY + +GK+ IV GF G + G TLGRGGSD +AVAL +L ++ I ++V+G++T
Sbjct: 9 IYRALSAGKVVIVAGFQGVDEAGDITTLGRGGSDTTAVALAAVLKADECQIYTDVDGVYT 68
Query: 212 ADPKLVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKI-LMLFGRTNNWRMGTV 270
DP++ P AR + +S+ E L A G K +Q ++ E A + + + + ++ GT+
Sbjct: 69 TDPRIEPRARKLEQISFVEMLEMASLGSKVLQIRSVEFAGKYHVPVRVLSSFSDDETGTL 128
Query: 271 ISNRTSRMPLMTYKDGL 287
IS+ + T+ G+
Sbjct: 129 ISSVEGAIIEATHVTGI 145
>pir||C83531 aspartate kinase alpha and beta chain PA0904 [imported] -
Pseudomonas aeruginosa (strain PAO1)
>gi|9946806|gb|AAG04293.1|AE004525_1 (AE004525)
aspartate kinase alpha and beta chain [Pseudomonas
aeruginosa]
Length = 412
Score = 76.9 bits (186), Expect = 4e-13
Identities = 84/310 (27%), Positives = 137/310 (44%), Gaps = 45/310 (14%)
Query: 4 MIVLKFGGSSVKN-DFHEAVSLTKSIFEEK--EVAVVVSALKGITDMLIKYAKTFDSKYA 60
+IV KFGG+SV + E V+ F E +V VVVSA+ G T+ LI A +
Sbjct: 3 LIVQKFGGTSVGTVERIEQVAEKVKKFREAGDDVVVVVSAMSGETNRLIGLANQIMEQPV 62
Query: 61 IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
+ D V + +T +LS+ + V
Sbjct: 63 PRELDVMVSTG-------------------------EQVTIALLSMALIKRGVPAVSYTG 97
Query: 121 GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVG-GMDGYRVTL 179
QV + SA+ K ID + + K +G++ +V GF G +G TL
Sbjct: 98 NQVRILTD--SAHTKARILHIDDTHIRADLK-------AGRVVVVAGFQGVDGNGNITTL 148
Query: 180 GRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAKHGM 239
GRGGSD + VAL L ++ I ++V+G++T DP++VP AR + +++EE L A G
Sbjct: 149 GRGGSDTTGVALAAALKADECQIYTDVDGVYTTDPRVVPQARRLDKITFEEMLEMASLGS 208
Query: 240 KAIQWKAAELAKEKKILMLFGRTNNWRMGTVIS----NRTSRMPLMTYKDGLLLINVEEE 295
K +Q +A E A + + + + GT+I+ + P+++ G+ E +
Sbjct: 209 KVLQIRAVEFAGKYNVPLRVLHSFQEGPGTLITIDDEEESMEQPIIS---GIAFNRDEAK 265
Query: 296 LEYRVIDEGP 305
L R + + P
Sbjct: 266 LTIRGVPDTP 275
>pir||T39822 aspartate kinase - fission yeast (Schizosaccharomyces pombe)
>gi|3080523|emb|CAA18652.1| (AL022599) aspartate kinase
[Schizosaccharomyces pombe]
Length = 519
Score = 76.5 bits (185), Expect = 5e-13
Identities = 77/278 (27%), Positives = 129/278 (45%), Gaps = 47/278 (16%)
Query: 5 IVLKFGGSSV-KNDFHEAVSLTKSIFEEKEVAVVVSA------LKGITDMLIKYAKTFDS 57
+V KFGG+SV K AV + K K VA+V SA +G T LI+ A
Sbjct: 16 VVQKFGGTSVGKFPIKIAVDVAKEYLSTKRVALVCSARSTDTKAEGTTTRLIR-ATEAAL 74
Query: 58 KYAIKIADSYVKFARTN------------GVDPNILSP------HIQELFNPPSLPKDA- 98
+ A+ V+ T+ G+ ++ +++ N + +
Sbjct: 75 RPAVGSVHDLVRIIETDHVQAARDFIQDVGIQDELIDAFHADCVELEQYLNAIRVLSEVS 134
Query: 99 --LTDYILSIGELLSAVIFAEVVEGQVIYPWELFSAYGKFGDGFIDLKKSKKN------- 149
D ++ +GE LS A V++ Q I + ++ ID ++ +N
Sbjct: 135 PRTRDLVIGMGERLSCRFMAAVLKDQGIDSEFIDMSH------IIDEQREWRNLDASFYA 188
Query: 150 ---AKIIYEVIDSG-KIPIVPGFVGGMDGYRVT-LGRGGSDYSAVALGVILNSELVAIMS 204
+++ +V G K+P+V GF G + G ++ +GRG +D+ A L V LN++ + I
Sbjct: 189 YLASQLASKVTAVGNKVPVVTGFFGMVPGGLLSQIGRGYTDFCAALLAVGLNADELQIWK 248
Query: 205 NVEGIFTADPKLVPSARLIPYLSYEEALIAAKHGMKAI 242
V+GIFTADP+ VP+ARL+P ++ EEA +G + I
Sbjct: 249 EVDGIFTADPRKVPTARLLPLITPEEAAELTYYGSEVI 286
>pir||S76764 hypothetical protein - Synechocystis sp. (strain PCC 6803)
>gi|1653765|dbj|BAA18676.1| (D90916) aspartate kinase
[Synechocystis sp.]
Length = 600
Score = 74.9 bits (181), Expect = 1e-12
Identities = 71/254 (27%), Positives = 119/254 (45%), Gaps = 40/254 (15%)
Query: 4 MIVLKFGGSSVKN-DFHEAVS--LTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
+IV KFGG+SV + +AV+ + +++ + VVVSA+ TD+L+ A+
Sbjct: 3 LIVQKFGGTSVGTVERIQAVAQRIKRTVQGGNSLVVVVSAMGKSTDVLVDLAQQISPNPC 62
Query: 61 IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
+ D + V +LS +QE+ P I G + V AE
Sbjct: 63 RREMDMLLSTGEQ--VSIALLSLALQEIDQPA----------ISLTGAQVGIVTEAEHSR 110
Query: 121 GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVG--GMDGYRVT 178
+++ +++ + + + GK+ +V GF G ++ +T
Sbjct: 111 ARIL-----------------EIRPDR-----LEHHLREGKVVVVAGFQGISSVEHLEIT 148
Query: 179 -LGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAKH 237
LGRGGSD SAVAL L ++ I ++V GI T DP+LVP A+L+ ++ +E L A
Sbjct: 149 TLGRGGSDTSAVALAAALKADFCEIYTDVPGILTTDPRLVPEAQLMAEITCDEMLELASL 208
Query: 238 GMKAIQWKAAELAK 251
G K + +A E+A+
Sbjct: 209 GAKVLHPRAVEIAR 222
>dbj|BAA95630.1| (AB042521) aspartate kinase [Oryza sativa]
Length = 354
Score = 71.0 bits (171), Expect = 2e-11
Identities = 41/116 (35%), Positives = 65/116 (55%), Gaps = 3/116 (2%)
Query: 162 IPIVPGFVGG--MDGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPS 219
IPIV GF+G G TLGRGGSD +A +G L + + +V+G+ T DP + P+
Sbjct: 64 IPIVTGFLGKGWKSGAVTTLGRGGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIYPN 123
Query: 220 ARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRM-GTVISNR 274
A +PYL++EEA A G + + ++ A+E I + + N + GT+I+ +
Sbjct: 124 ATTVPYLTFEEAAELAYFGAQVLHPQSMRPAREGDIPVRVKNSYNPKAPGTLITKQ 179
>pir||T04752 aspartate kinase (EC 2.7.2.4) / homoserine dehydrogenase (EC
1.1.1.3) T16H5.70 - Arabidopsis thaliana
>gi|3250680|emb|CAA19688.1| (AL024486) aspartate
kinase-homoserine dehydrogenase-like protein
[Arabidopsis thaliana] >gi|7268767|emb|CAB78973.1|
(AL161551) aspartate kinase-homoserine
dehydrogenase-like protein [Arabidopsis thaliana]
Length = 916
Score = 69.5 bits (167), Expect = 6e-11
Identities = 70/260 (26%), Positives = 117/260 (44%), Gaps = 43/260 (16%)
Query: 6 VLKFGGSSVKNDFHEAVSLTKSIFEE--KEVAVVVSALKGITDM---LIKYAKTFDSKY- 59
V KFGG+ V N ++ + I + + VVVSA+ +TDM LI+ A++ D Y
Sbjct: 91 VHKFGGTCVGNS-QRIRNVAEVIINDNSERKLVVVSAMSKVTDMMYDLIRKAQSRDDSYL 149
Query: 60 -AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPK-------------DALTDYILS 105
A++ + + +D + L+ + L N S K ++ +D++
Sbjct: 150 SALEAVLEKHRLTARDLLDGDDLASFLSHLHNDISNLKAMLRAIYIAGHASESFSDFVAG 209
Query: 106 IGELLSAVIFAEVVEGQ-------------VIYPWELFSAYGKFGDGFIDLKKSKKNAKI 152
GEL SA + + VV ++ P FG+ L K
Sbjct: 210 HGELWSAQMLSYVVRKTGLECKWMDTRDVLIVNPTSSNQVDPDFGESEKRLDK------- 262
Query: 153 IYEVIDSGKIPIVPGFVGGM-DGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFT 211
+ ++ KI I GF+ TL R GSD+SA +G +L + V I ++V+G+++
Sbjct: 263 -WFSLNPSKIIIATGFIASTPQNIPTTLKRDGSDFSAAIMGALLRARQVTIWTDVDGVYS 321
Query: 212 ADPKLVPSARLIPYLSYEEA 231
ADP+ V A ++ LSY+EA
Sbjct: 322 ADPRKVNEAVILQTLSYQEA 341
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.320 0.139 0.400
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 134894577
Number of Sequences: 2977
Number of extensions: 5652565
Number of successful extensions: 13051
Number of sequences better than 1.0e-10: 65
Number of HSP's better than 0.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 41
Number of HSP's that attempted gapping in prelim test: 12937
Number of HSP's gapped (non-prelim): 92
length of query: 368
length of database: 189,106,746
effective HSP length: 56
effective length of query: 312
effective length of database: 155,591,474
effective search space: 48544539888
effective search space used: 48544539888
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 166 (69.1 bits)