BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1674 (lysC-like1) DE:aspartate kinase (lysC) related
         (368 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||B75081 aspartate kinase (lysc) related PAB1674 - Pyrococcus...   735  0.0
pir||C71103 probable aspartokinase - Pyrococcus horikoshii >gi|3...   443  e-123
pir||A75081 aspartate kinase related (lysc) PAB1675 - Pyrococcus...   250  2e-65
pir||F71136 hypothetical protein PH0858 - Pyrococcus horikoshii ...   210  3e-53
sp|Q57991|AK_METJA PROBABLE ASPARTOKINASE (ASPARTATE KINASE) >gi...   123  4e-27
gi|11498307 aspartate kinase (lysC) [Archaeoglobus fulgidus] >gi...   115  9e-25
sp|P57290|AKH_BUCAI BIFUNCTIONAL ASPARTOKINASE/HOMOSERINE DEHYDR...   109  5e-23
pir||C46665 aspartate kinase (EC 2.7.2.4) I - Bacillus subtilis ...   106  4e-22
sp|Q04795|AK1_BACSU ASPARTOKINASE 1 (ASPARTOKINASE I) (ASPARTATE...   106  4e-22
pir||E81405 aspartate kinase (EC 2.7.2.4) alpha and beta chains ...   105  1e-21
pir||H72364 aspartokinase II - Thermotoga maritima (strain MSB8)...   104  2e-21
sp|P08660|AK3_ECOLI LYSINE-SENSITIVE ASPARTOKINASE III (ASPARTAT...   103  3e-21
gb|AAA24095.1| (M11812) aspartokinase III [Escherichia coli]          103  4e-21
sp|O25827|AK_HELPY ASPARTOKINASE (ASPARTATE KINASE) >gi|7434553|...   102  8e-21
dbj|BAB06119.1| (AP001515) aspartokinase I (alpha and beta subun...   100  4e-20
sp|Q9ZJZ7|AK_HELPJ ASPARTOKINASE (ASPARTATE KINASE) >gi|7434552|...    98  2e-19
sp|P44505|AKH_HAEIN BIFUNCTIONAL ASPARTOKINASE/HOMOSERINE DEHYDR...    97  3e-19
dbj|BAA38474.1| (D10385) aspartokinase I-homoserine dehydrogenas...    97  3e-19
sp|P27725|AK1H_SERMA BIFUNCTIONAL ASPARTOKINASE/HOMOSERINE DEHYD...    97  4e-19
dbj|BAA38477.1| (D10386) aspartokinase I-homoserine dehydrogenas...    97  4e-19
dbj|BAA38480.1| (D10387) aspartokinase I-homoserine dehydrogenas...    97  4e-19
pir||DEECK thrA bifunctional enzyme - Escherichia coli >gi|53724...    96  8e-19
sp|P00561|AK1H_ECOLI BIFUNCTIONAL ASPARTOKINASE/HOMOSERINE DEHYD...    95  1e-18
sp|P41403|AK_MYCSM ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: A...    94  2e-18
pir||E72715 probable aspartate kinase APE1140 - Aeropyrum pernix...    94  2e-18
emb|CAA23660.1| (V00361) thrA gene [EC 2.7.2.4 and EC 1.1.1.3] [...    94  3e-18
sp|P26512|AK_CORGL ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: A...    93  4e-18
gb|AAD49567.1|AF134837_1 (AF134837) aspartokinase subunit A [Amy...    91  2e-17
sp|P41398|AK_CORFL ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: A...    91  2e-17
sp|P53553|AK2_BACST ASPARTOKINASE 2 (ASPARTOKINASE II) (ASPARTAT...    89  6e-17
sp|Q59229|AK2_BACSP ASPARTOKINASE 2 (ASPARTOKINASE II) (ASPARTAT...    89  8e-17
sp|Q9ZCI7|AK_RICPR ASPARTOKINASE (ASPARTATE KINASE) >gi|7434558|...    89  8e-17
pir||H82086 aspartokinase I/homoserine dehydrogenase, threonine-...    89  1e-16
pir||T35383 probable aspartokinase - Streptomyces coelicolor >gi...    89  1e-16
sp|O67221|AK_AQUAE ASPARTOKINASE (ASPARTATE KINASE) >gi|7434554|...    89  1e-16
gb|AAD41796.1| (AF135862) precursor monofunctional aspartokinase...    89  1e-16
emb|CAA99580.1| (Z75208) aspartokinase II alpha subunit [Bacillu...    88  1e-16
pir||F82328 aspartokinase III, lysine-sensitive VC0391 [imported...    88  2e-16
pir||B69207 aspartokinase II alpha subunit - Methanobacterium th...    87  2e-16
pir||T48575 aspartate kinase - Arabidopsis thaliana >gi|7529283|...    87  2e-16
dbj|BAB08285.1| (AB007650) lysine-sensitive aspartate kinase [Ar...    87  2e-16
pir||H81865 aspartate kinase (EC 2.7.2.4) NMA1701 [imported] - N...    87  2e-16
sp|P77991|AK_THEFL ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: A...    87  2e-16
emb|CAA67376.1| (X98873) aspartate kinase [Arabidopsis thaliana]       87  3e-16
sp|P08495|AK2_BACSU ASPARTOKINASE 2 (ASPARTOKINASE II) (ASPARTAT...    87  3e-16
pir||A82311 aspartokinase, alpha and beta chains VC0547 [importe...    86  5e-16
pir||F81076 aspartokinase, alpha and beta chains NMB1498 [import...    86  5e-16
sp|P97151|AK_THETH ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: A...    86  7e-16
gb|AAB49995.1| (U90239) aspartokinase [Mycobacterium tuberculosis]     85  1e-15
sp|P97048|AK_MYCTU ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: A...    85  1e-15
gb|AAK41163.1| Aspartokinase (akH) [Sulfolobus solfataricus]           85  2e-15
dbj|BAB06815.1| (AP001517) aspartokinase II alpha and beta subun...    85  2e-15
pir||G72245 aspartokinase II - Thermotoga maritima (strain MSB8)...    84  2e-15
gb|AAF03452.1|AC010797_28 (AC010797) putative aspartate kinase [...    84  3e-15
emb|CAC06395.1| (Y16255) aspartate kinase [Arabidopsis thaliana]       83  4e-15
gb|AAB63104.1| (U62020) lysine-sensitive aspartate kinase [Arabi...    83  6e-15
pir||D81681 aspartokinase III TC0641 [imported] - Chlamydia muri...    82  8e-15
emb|CAC11508.1| (AL445064) aspartate kinase related protein [The...    81  2e-14
pir||F75405 aspartate kinase - Deinococcus radiodurans (strain R...    80  3e-14
emb|CAB57346.1| (Y15939) aspartokinase [Dichelobacter nodosus]         80  5e-14
pir||C83531 aspartate kinase alpha and beta chain PA0904 [import...    77  4e-13
pir||T39822 aspartate kinase - fission yeast (Schizosaccharomyce...    76  5e-13
pir||S76764 hypothetical protein - Synechocystis sp. (strain PCC...    75  1e-12
dbj|BAA95630.1| (AB042521) aspartate kinase [Oryza sativa]             71  2e-11
pir||T04752 aspartate kinase (EC 2.7.2.4) / homoserine dehydroge...    69  6e-11

>pir||B75081 aspartate kinase (lysc) related PAB1674 - Pyrococcus abyssi
           (strain Orsay) >gi|5458463|emb|CAB49951.1| (AJ248286)
           aspartate kinase (lysC) related [Pyrococcus abyssi]
           Length = 368
           
 Score =  735 bits (1878), Expect = 0.0
 Identities = 368/368 (100%), Positives = 368/368 (100%)

Query: 1   MRKMIVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
           MRKMIVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA
Sbjct: 1   MRKMIVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60

Query: 61  IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
           IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE
Sbjct: 61  IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120

Query: 121 GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMDGYRVTLG 180
           GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMDGYRVTLG
Sbjct: 121 GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMDGYRVTLG 180

Query: 181 RGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAKHGMK 240
           RGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAKHGMK
Sbjct: 181 RGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAKHGMK 240

Query: 241 AIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDGLLLINVEEELEYRV 300
           AIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDGLLLINVEEELEYRV
Sbjct: 241 AIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDGLLLINVEEELEYRV 300

Query: 301 IDEGPFWKLYDVPGNEGIRIIRELHKAIFGNVLSMLQEPGKHIRINRHKVGKSFEHMTFN 360
           IDEGPFWKLYDVPGNEGIRIIRELHKAIFGNVLSMLQEPGKHIRINRHKVGKSFEHMTFN
Sbjct: 301 IDEGPFWKLYDVPGNEGIRIIRELHKAIFGNVLSMLQEPGKHIRINRHKVGKSFEHMTFN 360

Query: 361 QSFSRKFY 368
           QSFSRKFY
Sbjct: 361 QSFSRKFY 368


>pir||C71103 probable aspartokinase - Pyrococcus horikoshii
           >gi|3257502|dbj|BAA30185.1| (AP000004) 346aa long
           hypothetical aspartokinase [Pyrococcus horikoshii]
           Length = 346
           
 Score =  443 bits (1126), Expect = e-123
 Identities = 205/327 (62%), Positives = 276/327 (83%), Gaps = 1/327 (0%)

Query: 3   KMIVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYAIK 62
           KMIV+KFGGSS++++F  AVSL K++ EEK+V VVVSALKGITD+L KY  TFDS+YA++
Sbjct: 6   KMIVIKFGGSSLRSEFKSAVSLIKALSEEKDVVVVVSALKGITDLLEKYTDTFDSRYAVE 65

Query: 63  IADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVEGQ 122
           ++ +Y++F +  G+D + LSP++++LFNPP LP  AL DYILSIGELLSA + AE   G 
Sbjct: 66  VSKTYLEFGKRMGIDTSSLSPYLKQLFNPPDLPPQALRDYILSIGELLSAAMIAEKANGA 125

Query: 123 VIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMDGYRVTLGRG 182
           VI+PW+LF A+G FG+GFID+KKSK+N K++ E ++SGKIPI+PGF+  ++GYRVTLGRG
Sbjct: 126 VIFPWDLFVAHGSFGNGFIDIKKSKRNVKLVKEALESGKIPIIPGFIANLNGYRVTLGRG 185

Query: 183 GSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAKHGMKAI 242
           GSDYSAVALGV+LNSELVAIMS+VEGIFTADPK++P + LIPY+SY+E LIA+K+GM+AI
Sbjct: 186 GSDYSAVALGVLLNSELVAIMSDVEGIFTADPKMIPYSLLIPYMSYDEILIASKYGMEAI 245

Query: 243 QWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDG-LLLINVEEELEYRVI 301
           QWKAA+LAKE + L+LFGR ++WRMGTV+SN +S MPL++Y  G LL++N++ E+ Y V+
Sbjct: 246 QWKAAKLAKEYEALILFGRASDWRMGTVVSNSSSHMPLLSYDQGKLLVMNMDSEIPYEVV 305

Query: 302 DEGPFWKLYDVPGNEGIRIIRELHKAI 328
           +EG FW++Y VP  + I+II+ELH+ I
Sbjct: 306 EEGEFWRVYRVPKRDSIKIIKELHRKI 332


>pir||A75081 aspartate kinase related (lysc) PAB1675 - Pyrococcus abyssi
           (strain Orsay) >gi|5458462|emb|CAB49950.1| (AJ248286)
           aspartate kinase related (lysC) [Pyrococcus abyssi]
           Length = 352
           
 Score =  250 bits (631), Expect = 2e-65
 Identities = 136/287 (47%), Positives = 192/287 (66%), Gaps = 13/287 (4%)

Query: 3   KMIVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYAIK 62
           K++V+KFGGSSV+  F EA+ L K + E   + VVVSALKG+TD LI++A   D     +
Sbjct: 4   KLLVVKFGGSSVRYAFEEALELVKYLSERIPIVVVVSALKGVTDELIRFANG-DKGALPR 62

Query: 63  IADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE-- 120
           I   + +F   +G++  I     +++      P +AL D I+S+GE +SA IFAE +E  
Sbjct: 63  IERIHEEFLNYHGLNTKISISFRKDM------PPEALRDEIISLGERISAKIFAEGLELL 116

Query: 121 ---GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMDGYRV 177
               +V+ P E   A G+FGD +I++++SK+ A  +  +I SG IP++PGF G ++G+RV
Sbjct: 117 GIKSKVVDPLEFLIAKGEFGDAYINIQESKRRAGKLIRLIKSGVIPVIPGFYGNLNGFRV 176

Query: 178 TLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAKH 237
           T GRGGSDYSA AL  IL+S  V IMS+VEGIFTADPKLVPSARLIPYLSYEE  +AAK 
Sbjct: 177 TFGRGGSDYSATALARILDSRCVLIMSDVEGIFTADPKLVPSARLIPYLSYEEIKVAAKL 236

Query: 238 GMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYK 284
           GMKA+ WKA +      I ++FG+T +W+ GT++ N  S  P++ ++
Sbjct: 237 GMKALHWKAVD-PVVGDIPIIFGKTKDWKFGTIVLNARSNFPIIVHR 282


>pir||F71136 hypothetical protein PH0858 - Pyrococcus horikoshii
           >gi|3257269|dbj|BAA29952.1| (AP000003) 359aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 359
           
 Score =  210 bits (528), Expect = 3e-53
 Identities = 119/345 (34%), Positives = 204/345 (58%), Gaps = 16/345 (4%)

Query: 1   MRKMIVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
           + K +V+KFGG+SV+  F EA+ L   + E  ++ VVVSAL G+TD L++ AK  D    
Sbjct: 2   VEKPVVIKFGGTSVRYAFEEALELVAKLHENMKIIVVVSALAGVTDCLLRLAKG-DKSAL 60

Query: 61  IKIADSYVKFARTNGVDPNILSPHIQELFNPPS-LPKD-ALTDYILSIGELLSAVIFAEV 118
           ++I + + + ++   V    L   +++  N  S  P + A  D I S GE  SA +F+E 
Sbjct: 61  LEIDEIHEELSQELNVQLEHLIHQLKKTINSKSSFPSEKAFIDEIASFGERFSAKLFSEG 120

Query: 119 VE-----GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMD 173
           ++      + +   ++    G+FG+  ++ KKS +   ++Y ++  G +P+V G+ G ++
Sbjct: 121 LKILGITARPVDSKDVLFVKGEFGNAEVEFKKSAQGVDVLYRMLRRGIVPVVTGYYGNLN 180

Query: 174 GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALI 233
           G+R T GRGGSDYSA ++  ++N++ V IMS+VEGI+TADPKLVP ARLI Y+SY+EA  
Sbjct: 181 GFRATFGRGGSDYSATSIASLVNAKAVLIMSDVEGIYTADPKLVPPARLIHYISYKEAKT 240

Query: 234 AAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYK-------DG 286
           AAK GMK +  +A +   E KI ++ G+T + + GT+IS+ +  +P++T+K         
Sbjct: 241 AAKLGMKVLHPRAID-PVEGKIPVILGKTRDLKFGTLISHESQGIPIVTHKLLENHAEIS 299

Query: 287 LLLINVEEELEYRVIDEGPFWKLYDVPGNEGIRIIRELHKAIFGN 331
           ++ +     L Y V +EG  +       ++ + ++R++H+ +  N
Sbjct: 300 VVSVKTNIPLPYEVYEEGDLYFKIKTSKDQFLEVLRDVHRRVVEN 344


>sp|Q57991|AK_METJA PROBABLE ASPARTOKINASE (ASPARTATE KINASE) >gi|2127773|pir||C64371
           aspartate kinase (EC 2.7.2.4) I - Methanococcus
           jannaschii >gi|1591278|gb|AAB98565.1| (U67506) aspartate
           kinase (lysC) [Methanococcus jannaschii]
           Length = 473
           
 Score =  123 bits (305), Expect = 4e-27
 Identities = 102/303 (33%), Positives = 154/303 (50%), Gaps = 41/303 (13%)

Query: 6   VLKFGGSSVKNDF---HEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAK-TFDSKYAI 61
           V+KFGG+SV +     H A  +TK   E+ +V VVVSA+  +T+ L++ ++   D +   
Sbjct: 4   VMKFGGTSVGSGERIRHVAKIVTKRKKEDDDVVVVVSAMSEVTNALVEISQQALDVRDIA 63

Query: 62  KIADSYVKFARTN---GVDPNILSPHIQE--------------------LFNPPSLPKDA 98
           K+ D ++KF R      ++  I S  I+E                     +     PK  
Sbjct: 64  KVGD-FIKFIREKHYKAIEEAIKSEEIKEEVKKIIDSRIEELEKVLIGVAYLGELTPKSR 122

Query: 99  LTDYILSIGELLSAVIFAEVVE--GQVIYPWELFSAY----GKFGDGFIDLKKSKKNAKI 152
             DYILS GE LS+ I +  +   G+     E   A       FG   +   + K+    
Sbjct: 123 --DYILSFGERLSSPILSGAIRDLGEKSIALEGGEAGIITDNNFGSARVKRLEVKER--- 177

Query: 153 IYEVIDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFT 211
           +  ++  G IP+V GF+G  + GY  TLGRGGSDYSA  +G  L+++++ I ++V G++T
Sbjct: 178 LLPLLKEGIIPVVTGFIGTTEEGYITTLGRGGSDYSAALIGYGLDADIIEIWTDVSGVYT 237

Query: 212 ADPKLVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRT-NNWRMGTV 270
            DP+LVP+AR IP LSY EA+  A  G K +  +  E A EK I +L   T      GT+
Sbjct: 238 TDPRLVPTARRIPKLSYIEAMELAYFGAKVLHPRTIEPAMEKGIPILVKNTFEPESEGTL 297

Query: 271 ISN 273
           I+N
Sbjct: 298 ITN 300


>gi|11498307 aspartate kinase (lysC) [Archaeoglobus fulgidus]
           >gi|7448935|pir||D69337 aspartate kinase (lysC) homolog
           - Archaeoglobus fulgidus >gi|2649914|gb|AAB90539.1|
           (AE001056) aspartate kinase (lysC) [Archaeoglobus
           fulgidus]
           Length = 462
           
 Score =  115 bits (285), Expect = 9e-25
 Identities = 105/310 (33%), Positives = 149/310 (47%), Gaps = 46/310 (14%)

Query: 5   IVLKFGGSSVKN--DFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA-- 60
           IV+KFGG SVK+  + +   +L K   E  EV VVVSA++G+TD L+K A    S+ +  
Sbjct: 3   IVMKFGGVSVKDGENIYHCANLVKKFSEGNEVVVVVSAMQGVTDALLKAAHRCCSEPSAG 62

Query: 61  ---IKIADSY------VKFARTNGVDPNILSPHIQELFNPPSLPKDAL------------ 99
              + IAD        +++A  N      +   ++ L +   L K  L            
Sbjct: 63  FIKMFIADMMKRHYEAIEYAVRNDEIKAKVIAAVERLLD--ELEKVLLGISYLGELTRRS 120

Query: 100 TDYILSIGELLSAVIFAEVVEGQVIYPWELFSAYGKFGDGFIDLKKSKKNAKI---IYEV 156
            DYI+S GE LSA IF+  +    +    L       GD  I   ++   AK    +Y  
Sbjct: 121 EDYIVSFGERLSAPIFSAALLSLGVDSVALTG-----GDAGIITDRNFGRAKPLPGVYTT 175

Query: 157 IDS---------GKIPIVPGFVGGM-DGYRVTLGRGGSDYSAVALGVILNSELVAIMSNV 206
           I +           IP+V GF+G   DG   TLGRGGSDY+A  L   L+++ V +   V
Sbjct: 176 IRNRLEPLLTIKKTIPVVTGFIGATDDGSITTLGRGGSDYTATILAAALDADEVWLWKEV 235

Query: 207 EGIFTADPKLVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRT-NNW 265
           +GI T DPK VP+AR+IP +SY+EA+  +  G K +  +A E    K I +    T N  
Sbjct: 236 DGIMTCDPKYVPNARVIPEISYQEAMELSHFGAKILHPRALEPVMRKNIPVRIKNTFNPD 295

Query: 266 RMGTVISNRT 275
             GTVI   T
Sbjct: 296 APGTVIGPTT 305


>sp|P57290|AKH_BUCAI BIFUNCTIONAL ASPARTOKINASE/HOMOSERINE DEHYDROGENASE (AK-HD)
           [INCLUDES: ASPARTOKINASE ; HOMOSERINE DEHYDROGENASE ]
           >gi|10038876|dbj|BAB12911.1| (AP001118) aspartokinase I
           / homoserine dehydrogenase I [Buchnera sp. APS]
           Length = 816
           
 Score =  109 bits (270), Expect = 5e-23
 Identities = 94/324 (29%), Positives = 158/324 (48%), Gaps = 38/324 (11%)

Query: 4   MIVLKFGGSSVKN--DFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYA----KTFDS 57
           M +LKFGG+S+ N   F    S+ +   +  ++AVV+SA   IT+ L+K      K    
Sbjct: 1   MKLLKFGGTSLANAEKFLSVSSIIEENTQTDQIAVVLSAPAKITNYLVKIIENTIKNNQI 60

Query: 58  KYAIKIADSYVKFARTNGVDPNILSPH-----------------IQELFNPPSLPKDALT 100
              + +A++       N ++     PH                 IQ +      P D + 
Sbjct: 61  LETVHLAENIFMQLINNFLNIQSNFPHKEIEKIIKKEFNELKNIIQGILLLKQCP-DNIR 119

Query: 101 DYILSIGELLSAVIFAEVVEGQ-----VIYPWELFSAYG-KFGDGFIDLKKSKKNAKIIY 154
             I+S GE+LS  I   +++ +     +I P +   A G  + D  +D+ +SKKN + + 
Sbjct: 120 AIIISRGEILSVFIMKSILQSKNYNVTIINPVKNLVAIGDNYLDSTVDISESKKNIQNMN 179

Query: 155 EVIDSGKIPIVPGFVGG-MDGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTAD 213
             I+   I ++ GF+ G  D   V LGR GSDYSA  L   L++    I ++V+G+FT+D
Sbjct: 180 --INQSNIILMAGFIAGNKDKKLVVLGRNGSDYSAAVLAACLDANCCEIWTDVDGVFTSD 237

Query: 214 PKLVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWR-MGTVIS 272
           P+ VP+ARL+  +SY+EA+  +  G K +  +  E   + KI  L   TNN + +GT+I 
Sbjct: 238 PRKVPNARLLKSISYQEAMELSYFGAKVLHPRTIEPIAQFKIPCLIKNTNNVKSIGTLIC 297

Query: 273 NRTSR----MPLMTYKDGLLLINV 292
            +       +  +T+ D + + N+
Sbjct: 298 EQNCSEKDFLKGVTHLDEIAMFNI 321


>pir||C46665 aspartate kinase (EC 2.7.2.4) I - Bacillus subtilis
           >gi|142829|gb|AAA22384.1| (L08471) aspartokinase I
           [Bacillus subtilis]
           Length = 404
           
 Score =  106 bits (262), Expect = 4e-22
 Identities = 86/280 (30%), Positives = 140/280 (49%), Gaps = 37/280 (13%)

Query: 3   KMIVLKFGGSSVKNDFHEAVSL---TKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKY 59
           K+IV KFGG+SVK+D    ++L    ++I E  +V VVVSA+    D    YA   DS  
Sbjct: 2   KIIVQKFGGTSVKDDKGRKLALGHIKEAISEGYKVVVVVSAMGRKGD---PYAT--DSLL 56

Query: 60  AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVV 119
            +   D             + +SP  Q+L              +LS GE +S+V+F  ++
Sbjct: 57  GLLYGDQ------------SAISPREQDL--------------LLSCGETISSVVFTSML 90

Query: 120 EGQVIYPWELFSAYGKF--GDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMD-GYR 176
               +    L  A   F   D   + K  +   + ++ V+ +    +V GF G  + G  
Sbjct: 91  LDNGVKAAALTGAQAGFLTNDQHTNAKIIEMKPERLFSVLANHDAVVVAGFQGATEKGDT 150

Query: 177 VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAK 236
            T+GRGGSD SA ALG  +++E + I ++VEG+ TADP++V +A+ +P ++Y E    A 
Sbjct: 151 TTIGRGGSDTSAAALGAAVDAEYIDIFTDVEGVMTADPRVVENAKPLPVVTYTEICNLAY 210

Query: 237 HGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTS 276
            G K I  +A E+A + K+ +    T +   GT++++  S
Sbjct: 211 QGAKVISPRAVEIAMQAKVPIRVRSTYSNDKGTLVTSHHS 250


>sp|Q04795|AK1_BACSU ASPARTOKINASE 1 (ASPARTOKINASE I) (ASPARTATE KINASE 1) [CONTAINS:
           ASPARTOKINASE I ALPHA SUBUNIT; ASPARTOKINASE I BETA
           SUBUNIT] >gi|2634048|emb|CAB13549.1| (Z99112)
           aspartokinase I (alpha and beta subunits) [Bacillus
           subtilis]
           Length = 404
           
 Score =  106 bits (262), Expect = 4e-22
 Identities = 86/280 (30%), Positives = 140/280 (49%), Gaps = 37/280 (13%)

Query: 3   KMIVLKFGGSSVKNDFHEAVSL---TKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKY 59
           K+IV KFGG+SVK+D    ++L    ++I E  +V VVVSA+    D    YA   DS  
Sbjct: 2   KIIVQKFGGTSVKDDKGRKLALGHIKEAISEGYKVVVVVSAMGRKGD---PYAT--DSLL 56

Query: 60  AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVV 119
            +   D             + +SP  Q+L              +LS GE +S+V+F  ++
Sbjct: 57  GLLYGDQ------------SAISPREQDL--------------LLSCGETISSVVFTSML 90

Query: 120 EGQVIYPWELFSAYGKF--GDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMD-GYR 176
               +    L  A   F   D   + K  +   + ++ V+ +    +V GF G  + G  
Sbjct: 91  LDNGVKAAALTGAQAGFLTNDQHTNAKIIEMKPERLFSVLANHDAVVVAGFQGATEKGDT 150

Query: 177 VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAK 236
            T+GRGGSD SA ALG  +++E + I ++VEG+ TADP++V +A+ +P ++Y E    A 
Sbjct: 151 TTIGRGGSDTSAAALGAAVDAEYIDIFTDVEGVMTADPRVVENAKPLPVVTYTEICNLAY 210

Query: 237 HGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTS 276
            G K I  +A E+A + K+ +    T +   GT++++  S
Sbjct: 211 QGAKVISPRAVEIAMQAKVPIRVRSTYSNDKGTLVTSHHS 250


>pir||E81405 aspartate kinase (EC 2.7.2.4) alpha and beta chains Cj0582
           [imported] - Campylobacter jejuni (strain NCTC 11168)
           >gi|6968049|emb|CAB75218.1| (AL139075) aspartokinase,
           alpha and beta subunits [Campylobacter jejuni]
           Length = 400
           
 Score =  105 bits (259), Expect = 1e-21
 Identities = 94/326 (28%), Positives = 157/326 (47%), Gaps = 48/326 (14%)

Query: 4   MIVLKFGGSSVKN-DFHEAVS--LTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
           +IV K+GG+SV   +  EAV+  + +S  +  ++ VVVSA+ G+T+ LI+ A+ F     
Sbjct: 2   LIVQKYGGTSVGTLERIEAVANRVIQSAQQGNQLVVVVSAMSGVTNTLIEQAEYFSKT-- 59

Query: 61  IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
                        NG D                       D +LS GE +++ + + +  
Sbjct: 60  ------------PNGKD----------------------MDMLLSSGERVTSALLS-IAL 84

Query: 121 GQVIYPWELFSAY--GKFGDG-FIDLKKSKKNAKIIYEVIDSGKIPIVPGFVG-GMDGYR 176
            +   P   FS    G   D  F   +    + K I   + +GKI ++ GF G   +G  
Sbjct: 85  NEKGCPAISFSGRKAGIITDSVFTKARIHHIDTKAIKSELQNGKIVVIAGFQGVDEEGNV 144

Query: 177 VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAK 236
            TLGRGGSD SAVA+   LN++L  I ++V+G++T DP++ P A+ +  +SYEE L  A 
Sbjct: 145 TTLGRGGSDLSAVAVAGALNADLCEIYTDVDGVYTTDPRIEPKAKKLDKISYEEMLELAS 204

Query: 237 HGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDGLLLINVEEEL 296
            G K +Q ++ ELAK+  + ++   + N   GT+I+        +    G+ L   +  +
Sbjct: 205 LGAKVLQNRSVELAKKLNVNLVTRSSFNNNEGTMITKEDGMEQALV--SGIALDKNQARV 262

Query: 297 EYRVIDEGP--FWKLYDVPGNEGIRI 320
             R I++ P    +++ V  NE I +
Sbjct: 263 TLRNIEDKPGIAAEIFSVLANENINV 288


>pir||H72364 aspartokinase II - Thermotoga maritima (strain MSB8)
           >gi|4981061|gb|AAD35632.1|AE001729_12 (AE001729)
           aspartokinase II [Thermotoga maritima]
           Length = 739
           
 Score =  104 bits (256), Expect = 2e-21
 Identities = 87/310 (28%), Positives = 152/310 (48%), Gaps = 64/310 (20%)

Query: 4   MIVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAV----VVSALKGITDMLIKYAKTFDSKY 59
           ++V+KFGG+++ +D  +   + + I + K+  V    V+SA+   TD LI+ AKT D   
Sbjct: 340 VVVMKFGGAAI-SDVEKLEKVAEKIIKRKKSGVKPVVVLSAMGDTTDHLIELAKTIDE-- 396

Query: 60  AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVV 119
                                 +P  +EL            D +LS GE+ S  + +  +
Sbjct: 397 ----------------------NPDPREL------------DLLLSTGEIQSVALMSIAL 422

Query: 120 EGQVIYPWELFSAYG---------KFGDG-FIDLKKSKKNAKIIYEVIDSGKIPIVPGFV 169
             +    ++  S  G         ++G    ID+     N  II   +    IP+V GF 
Sbjct: 423 RKR---GYKAISFTGNQLKIITDKRYGSARIIDI-----NTDIISRYLKQDFIPVVAGFQ 474

Query: 170 GGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSY 228
           G  + G   TLGRGGSD +A+AL   L ++L  +  +V+G++TADP++V  AR+I  LS+
Sbjct: 475 GITETGDITTLGRGGSDLTAIALAYSLGADLCELYKDVDGVYTADPRIVKDARVIKELSW 534

Query: 229 EEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTS-RMPL---MTYK 284
           EE +  ++HG + +Q +AAE A++  + +L    +    GT+I   T    P+   +T++
Sbjct: 535 EEMIELSRHGAQVLQARAAEFARKYGVKVLIKNAHKETRGTLIWEGTKVENPIVRAVTFE 594

Query: 285 DGLLLINVEE 294
           DG+  + +++
Sbjct: 595 DGMAKVVLKD 604


>sp|P08660|AK3_ECOLI LYSINE-SENSITIVE ASPARTOKINASE III (ASPARTATE KINASE III)
           >gi|7428061|pir||KIECD3 aspartate kinase (EC 2.7.2.4)
           III, lysine-sensitive - Escherichia coli
           >gi|396359|gb|AAC43118.1| (U00006) aspartokinase III
           [Escherichia coli] >gi|1790455|gb|AAC76994.1| (AE000475)
           aspartokinase III, lysine sensitive [Escherichia coli
           K12]
           Length = 449
           
 Score =  103 bits (255), Expect = 3e-21
 Identities = 89/300 (29%), Positives = 151/300 (49%), Gaps = 22/300 (7%)

Query: 1   MRKMIVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAVVV-SALKGITDMLIKYAKTFDSKY 59
           M +++V KFGG+SV  DF         +  +  V +VV SA  GIT++L+  A+  +   
Sbjct: 1   MSEIVVSKFGGTSVA-DFDAMNRSADIVLSDANVRLVVLSASAGITNLLVALAEGLEPGE 59

Query: 60  AIKIADSY--VKFARTNGVD-PNILSPHIQELFNPPSLPKDA--------LTDYILSIGE 108
             +  D+   ++FA    +  PN++   I+ L    ++  +A        LTD ++S GE
Sbjct: 60  RFEKLDAIRNIQFAILERLRYPNVIREEIERLLENITVLAEAAALATSPALTDELVSHGE 119

Query: 109 LLSAVIFAEVV-EGQVIYPW----ELFSAYGKFGDGFIDLKKSKKNAKI-IYEVIDSGKI 162
           L+S ++F E++ E  V   W    ++     +FG    D+    + A + +   ++ G +
Sbjct: 120 LMSTLLFVEILRERDVQAQWFDVRKVMRTNDRFGRAEPDIAALAELAALQLLPRLNEGLV 179

Query: 163 PIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSAR 221
            I  GF+G  + G   TLGRGGSDY+A  L   L++  V I ++V GI+T DP++V +A+
Sbjct: 180 -ITQGFIGSENKGRTTTLGRGGSDYTAALLAEALHASRVDIWTDVPGIYTTDPRVVSAAK 238

Query: 222 LIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRM-GTVISNRTSRMPL 280
            I  +++ EA   A  G K +       A    I +  G + + R  GT++ N+T   PL
Sbjct: 239 RIDEIAFAEAAEMATFGAKVLHPATLLPAVRSDIPVFVGSSKDPRAGGTLVCNKTENPPL 298


>gb|AAA24095.1| (M11812) aspartokinase III [Escherichia coli]
           Length = 449
           
 Score =  103 bits (254), Expect = 4e-21
 Identities = 89/300 (29%), Positives = 151/300 (49%), Gaps = 22/300 (7%)

Query: 1   MRKMIVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAVVV-SALKGITDMLIKYAKTFDSKY 59
           M +++V KFGG+SV  DF         +  +  V +VV SA  GIT++L+  A+  +   
Sbjct: 1   MSEIVVSKFGGTSVA-DFDAMNRSADIVLSDANVRLVVLSASAGITNLLVALAEGLEPCE 59

Query: 60  AIKIADSY--VKFARTNGVD-PNILSPHIQELFNPPSLPKDA--------LTDYILSIGE 108
             +  D+   ++FA    +  PN++   I+ L    ++  +A        LTD ++S GE
Sbjct: 60  RFEKLDAIRNIQFAILERLRYPNVIREEIERLLENITVLAEAAALATSPALTDELVSHGE 119

Query: 109 LLSAVIFAEVV-EGQVIYPW----ELFSAYGKFGDGFIDLKKSKKNAKI-IYEVIDSGKI 162
           L+S ++F E++ E  V   W    ++     +FG    D+    + A + +   ++ G +
Sbjct: 120 LMSTLLFVEILRERDVQAQWFDVRKVMRTNDRFGRAEPDIAALAELAALQLLPRLNEGLV 179

Query: 163 PIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSAR 221
            I  GF+G  + G   TLGRGGSDY+A  L   L++  V I ++V GI+T DP++V +A+
Sbjct: 180 -ITQGFIGSENKGRTTTLGRGGSDYTAALLAEALHASRVDIWTDVPGIYTTDPRVVSAAK 238

Query: 222 LIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRM-GTVISNRTSRMPL 280
            I  +++ EA   A  G K +       A    I +  G + + R  GT++ N+T   PL
Sbjct: 239 RIDEIAFAEAAEMATFGAKVLHPATLLPAVRSDIPVFVGSSKDPRAGGTLVCNKTENPPL 298


>sp|O25827|AK_HELPY ASPARTOKINASE (ASPARTATE KINASE) >gi|7434553|pir||E64673
           aspartokinase - Helicobacter pylori (strain 26695)
           >gi|2314392|gb|AAD08274.1| (AE000628) aspartokinase
           (lysC) [Helicobacter pylori 26695]
           Length = 405
           
 Score =  102 bits (251), Expect = 8e-21
 Identities = 81/277 (29%), Positives = 133/277 (47%), Gaps = 48/277 (17%)

Query: 4   MIVLKFGGSS---VKNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
           +IV K+GG+S   ++   + A  + +S+    +V VVVSA+ G TD L+++ K F     
Sbjct: 2   LIVQKYGGTSMGSIERIHNVAQRVLESVTLGHQVVVVVSAMSGETDRLLEFGKNFSH--- 58

Query: 61  IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
                                +P+ +E+            D I+S+GEL+S+   +  +E
Sbjct: 59  ---------------------NPNKREM------------DRIVSVGELVSSAALSMALE 85

Query: 121 GQVIYPWELFSAYGK-----FGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGG-MDG 174
               Y     S  GK         F +      + K I E+++   I ++ GF G  + G
Sbjct: 86  R---YGHRAISLSGKEAGILTSSHFQNAVIQSIDTKRITELLEKNYIVVIAGFQGADIQG 142

Query: 175 YRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIA 234
              TLGRGGSD SAVAL   L + L  I ++V+G++T DP++   A+ I  +SY+E L  
Sbjct: 143 ETTTLGRGGSDLSAVALAGALKAHLCEIYTDVDGVYTTDPRIEEKAQKIAQISYDEMLEL 202

Query: 235 AKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVI 271
           A  G K +  ++ ELAK+  + ++   + N   GT+I
Sbjct: 203 ASMGAKVLLNRSVELAKKLSVKLVTRNSFNHSEGTLI 239


>dbj|BAB06119.1| (AP001515) aspartokinase I (alpha and beta subunits) [Bacillus
           halodurans]
           Length = 411
           
 Score = 99.8 bits (245), Expect = 4e-20
 Identities = 88/297 (29%), Positives = 138/297 (45%), Gaps = 49/297 (16%)

Query: 3   KMIVLKFGGSSVKN-DFHE--AVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKY 59
           K+I+ KFGG+SVK  +  E  A  + K++    +V VVVSA+                  
Sbjct: 2   KIIIQKFGGTSVKTAEVREMAAKHVEKAVEGGYKVVVVVSAMG----------------- 44

Query: 60  AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVV 119
             +  D Y        VD   ++   Q+L              ++S GE++S+V+F E++
Sbjct: 45  --RSGDPYATDTLLQLVDTKTIAKREQDL--------------LVSCGEIISSVVFTELL 88

Query: 120 EGQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGK-------IPIVPGFVG-G 171
             + I    +  A   F        +   NAKI+   +D  K       + +V GF G  
Sbjct: 89  LKKGIQATAMTGAQAGF-----RTNEEFTNAKIVDMKVDRLKKTLVHQDVVVVAGFQGQS 143

Query: 172 MDGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEA 231
             G   TLGRGGSD SA ALG  L++E V I ++VEGI TADP++V  AR +  ++Y E 
Sbjct: 144 PTGETTTLGRGGSDTSATALGAALDAEWVDIFTDVEGIMTADPRIVSEARPLDTMTYNEV 203

Query: 232 LIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDGLL 288
              A  G K I  +A E+A + KI +    T +   GT++++  +       +D ++
Sbjct: 204 CNMAYQGAKVIHPRAVEIAMQAKIPIHIRSTYSDGKGTLVTSMLTEAGARDVQDRII 260


>sp|Q9ZJZ7|AK_HELPJ ASPARTOKINASE (ASPARTATE KINASE) >gi|7434552|pir||H71843
           aspartokinase 2 alpha and beta chains - Helicobacter
           pylori  (strain J99) >gi|4155744|gb|AAD06723.1|
           (AE001542) ASPARTOKINASE 2 ALPHA AND BETA SUBUNITS
           [Helicobacter pylori J99]
           Length = 405
           
 Score = 97.5 bits (239), Expect = 2e-19
 Identities = 82/279 (29%), Positives = 133/279 (47%), Gaps = 52/279 (18%)

Query: 4   MIVLKFGGSS---VKNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
           +IV K+GG+S   ++   + A  + +S+    +V VVVSA+ G TD L+++ K F     
Sbjct: 2   LIVQKYGGTSMGSIERIHNVAQRVLESVKLGHQVVVVVSAMSGETDRLLEFGKNFSH--- 58

Query: 61  IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
                                +P+ +E+            D I+S GE +S+   +  +E
Sbjct: 59  ---------------------NPNKREM------------DRIVSAGEWISSAALSMALE 85

Query: 121 GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKI-------IYEVIDSGKIPIVPGFVGG-M 172
               Y     S  GK  +  I      +NA I       I E+++   I ++ GF G  +
Sbjct: 86  R---YGHRAISLSGK--EAGILTSSHFQNAVIQSIDTQRITELLEKNYIVVIAGFQGADI 140

Query: 173 DGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEAL 232
            G   TLGRGGSD SAVAL   L + L  I ++V+G++T DP++   A+ I  +SY+E L
Sbjct: 141 QGETTTLGRGGSDLSAVALAGALKAHLCEIYTDVDGVYTTDPRIEEKAQKIAQISYDEML 200

Query: 233 IAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVI 271
             A  G K +  ++ ELAK+  + ++   + N   GT+I
Sbjct: 201 ELASMGAKVLLNRSVELAKKLSVKLVTRNSFNHSEGTLI 239


>sp|P44505|AKH_HAEIN BIFUNCTIONAL ASPARTOKINASE/HOMOSERINE DEHYDROGENASE (AK-HD)
           [INCLUDES: ASPARTOKINASE ; HOMOSERINE DEHYDROGENASE ]
           >gi|1073872|pir||A64048 aspartate kinase (EC 2.7.2.4) I
           / homoserine dehydrogenase  (EC 1.1.1.3) - Haemophilus
           influenzae (strain Rd KW20) >gi|1573040|gb|AAC21767.1|
           (U32694) aspartokinase I / homoserine dehydrogenase I
           (thrA) [Haemophilus influenzae Rd]
           Length = 815
           
 Score = 97.1 bits (238), Expect = 3e-19
 Identities = 93/322 (28%), Positives = 150/322 (45%), Gaps = 35/322 (10%)

Query: 4   MIVLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAK------TF 55
           M VLKFGG+S+ N   F +A  L +    E++ A V+SA   IT+ L+  ++      + 
Sbjct: 1   MRVLKFGGTSLANPERFSQAAKLIEQAHLEEQAAGVLSAPAKITNHLVALSEKAALNQST 60

Query: 56  DSKY--AIKIADSYVKFART-------NGVDPNILSPHIQ-----ELFNPPSLPKDALTD 101
           D+ +  AI+I  + +    T       NG    I +  +Q     E        +DA+  
Sbjct: 61  DTHFNEAIEIFYNIINGLHTENNQFDLNGTKALIDAEFVQIKGLLEEIRQAGKVEDAVKA 120

Query: 102 YILSIGELLSAVIFAEVVEGQ-----VIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEV 156
            I   GE LS  +     E +     ++ P +   A G + +  +++++S K  ++    
Sbjct: 121 TIDCRGEKLSIAMMKAWFEARGYSVHIVDPVKQLLAKGGYLESSVEIEESTK--RVDAAN 178

Query: 157 IDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPK 215
           I   K+ ++ GF  G + G  V LGR GSDYSA  L   L + +  I ++V+G++T DP+
Sbjct: 179 IAKDKVVLMAGFTAGNEKGELVLLGRNGSDYSAACLAACLGASVCEIWTDVDGVYTCDPR 238

Query: 216 LVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNN-WRMGTVISNR 274
           LVP ARL+P LSY EA+  +  G K I  +       + I  +   T N    G++I   
Sbjct: 239 LVPDARLLPTLSYREAMELSYFGAKVIHPRTIGPLLPQNIPCVIKNTGNPSAPGSIIDGN 298

Query: 275 TSRMPL----MTYKDGLLLINV 292
                L    +T  D L + NV
Sbjct: 299 VKSESLQVKGITNLDNLAMFNV 320


>dbj|BAA38474.1| (D10385) aspartokinase I-homoserine dehydrogenase I [Serratia
           marcescens]
           Length = 819
           
 Score = 97.1 bits (238), Expect = 3e-19
 Identities = 101/351 (28%), Positives = 163/351 (45%), Gaps = 37/351 (10%)

Query: 4   MIVLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYA-KTFDSKYA 60
           M VLKFGG+SV N   F     + +S   + +VA V+SA   IT+ L+    KT   +  
Sbjct: 1   MRVLKFGGTSVANAERFLRVADIMESNARQGQVATVLSAPAKITNHLVAMIDKTVAGQDI 60

Query: 61  I-KIADSYVKFA----------------RTNGVDPNILSPHIQELFNPPSLPK--DALTD 101
           +  ++D+   FA                R  GV     +   Q L     L +  D++  
Sbjct: 61  LPNMSDAERIFADLLSGLAQALPGFEYDRLKGVVDQEFAQLKQVLHGVSLLGQCPDSVNA 120

Query: 102 YILSIGELLSAVIFAEVVEGQ-----VIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEV 156
            I+  GE LS  I   V   +     VI P E   A G + +  +D+ +S    +I    
Sbjct: 121 AIICRGEKLSIAIMEGVFRAKGYPVTVINPVEKLLAQGHYLESTVDIAES--TLRIAAAA 178

Query: 157 IDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPK 215
           I +  I ++ GF  G D G  V LGR GSDYSA  L   L ++   I ++V+G++T DP+
Sbjct: 179 IPADHIVLMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPR 238

Query: 216 LVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRM-GTVI--S 272
            VP ARL+  +SY+EA+  +  G K +  +      + +I  L   T+N +  GT+I   
Sbjct: 239 TVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTSNPQAPGTLIGKD 298

Query: 273 NRTSRMPL--MTYKDGLLLINVEEELEYRVIDEGPFWKLYDVPGNEGIRII 321
           +  + MP+  +T  + + +INV       ++D     +++ V    GI ++
Sbjct: 299 STDADMPVKGITNLNNMAMINVSGPGMKGMVDMAA--RVFAVMSRAGISVV 347


>sp|P27725|AK1H_SERMA BIFUNCTIONAL ASPARTOKINASE/HOMOSERINE DEHYDROGENASE I (AKI-HDI)
           [INCLUDES: ASPARTOKINASE I ; HOMOSERINE DEHYDROGENASE I
           ] >gi|421254|pir||B47057 aspartate kinase (EC 2.7.2.4) I
           / homoserine dehydrogenase  (EC 1.1.1.3) I - Serratia
           marcescens >gi|47273|emb|CAA43212.1| (X60821) aspartate
           kinase [Serratia marcescens]
           Length = 819
           
 Score = 96.7 bits (237), Expect = 4e-19
 Identities = 97/322 (30%), Positives = 152/322 (47%), Gaps = 35/322 (10%)

Query: 4   MIVLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYA-KTFDSKYA 60
           M VLKFGG+SV N   F     + +S   + +VA V+SA   IT+ L+    KT   +  
Sbjct: 1   MRVLKFGGTSVANAERFLRVADIMESNARQGQVATVLSAPAKITNHLVAMIDKTVAGQDI 60

Query: 61  I-KIADSYVKFA----------------RTNGVDPNILSPHIQELFNPPSLPK--DALTD 101
           +  ++D+   FA                R  GV     +   Q L     L +  D++  
Sbjct: 61  LPNMSDAERIFADLLSGLAQALPGFEYDRLKGVVDQEFAQLKQVLHGVSLLGQCPDSVNA 120

Query: 102 YILSIGELLSAVIFAEVVEGQ-----VIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEV 156
            I+  GE LS  I   V   +     VI P E   A G + +  +D+ +S    +I    
Sbjct: 121 AIICRGEKLSIAIMEGVFRAKGYPVTVINPVEKLLAQGHYLESTVDIAES--TLRIAAAA 178

Query: 157 IDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPK 215
           I +  I ++ GF  G D G  V LGR GSDYSA  L   L ++   I ++V+G++T DP+
Sbjct: 179 IPADHIVLMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPR 238

Query: 216 LVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRM-GTVI--S 272
            VP ARL+  +SY+EA+  +  G K +  +      + +I  L   T+N +  GT+I   
Sbjct: 239 TVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTSNPQAPGTLIGKD 298

Query: 273 NRTSRMPL--MTYKDGLLLINV 292
           +  + MP+  +T  + + +INV
Sbjct: 299 STDADMPVKGITNLNNMAMINV 320


>dbj|BAA38477.1| (D10386) aspartokinase I-homoserine dehydrogenase I [Serratia
           marcescens]
           Length = 819
           
 Score = 96.7 bits (237), Expect = 4e-19
 Identities = 97/322 (30%), Positives = 152/322 (47%), Gaps = 35/322 (10%)

Query: 4   MIVLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYA-KTFDSKYA 60
           M VLKFGG+SV N   F     + +S   + +VA V+SA   IT+ L+    KT   +  
Sbjct: 1   MRVLKFGGTSVANAERFLRVADIMESNARQGQVATVLSAPAKITNHLVAMIDKTVAGQDI 60

Query: 61  I-KIADSYVKFA----------------RTNGVDPNILSPHIQELFNPPSLPK--DALTD 101
           +  ++D+   FA                R  GV     +   Q L     L +  D++  
Sbjct: 61  LPNMSDAERIFADLLSGLAQALPGFEYDRLKGVVDQEFAQLKQVLHGVSLLGQCPDSVNA 120

Query: 102 YILSIGELLSAVIFAEVVEGQ-----VIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEV 156
            I+  GE LS  I   V   +     VI P E   A G + +  +D+ +S    +I    
Sbjct: 121 AIICRGEKLSIAIMEGVFRAKGYPVTVINPVEKLLAQGHYLESTVDIAES--TLRIAAAA 178

Query: 157 IDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPK 215
           I +  I ++ GF  G D G  V LGR GSDYSA  L   L ++   I ++V+G++T DP+
Sbjct: 179 IPADHIVLMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPR 238

Query: 216 LVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRM-GTVI--S 272
            VP ARL+  +SY+EA+  +  G K +  +      + +I  L   T+N +  GT+I   
Sbjct: 239 TVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTSNPQAPGTLIGKD 298

Query: 273 NRTSRMPL--MTYKDGLLLINV 292
           +  + MP+  +T  + + +INV
Sbjct: 299 STDADMPVKGITNLNNMAMINV 320


>dbj|BAA38480.1| (D10387) aspartokinase I-homoserine dehydrogenase I [Serratia
           marcescens]
           Length = 819
           
 Score = 96.7 bits (237), Expect = 4e-19
 Identities = 97/322 (30%), Positives = 152/322 (47%), Gaps = 35/322 (10%)

Query: 4   MIVLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYA-KTFDSKYA 60
           M VLKFGG+SV N   F     + +S   + +VA V+SA   IT+ L+    KT   +  
Sbjct: 1   MRVLKFGGTSVANAERFLRVADIMESNARQGQVATVLSAPAKITNHLVAMIDKTVAGQDI 60

Query: 61  I-KIADSYVKFA----------------RTNGVDPNILSPHIQELFNPPSLPK--DALTD 101
           +  ++D+   FA                R  GV     +   Q L     L +  D++  
Sbjct: 61  LPNMSDAERIFADLLSGLAQALPGFEYDRLKGVVDQEFAQLKQVLHGVSLLGQCPDSVNA 120

Query: 102 YILSIGELLSAVIFAEVVEGQ-----VIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEV 156
            I+  GE LS  I   V   +     VI P E   A G + +  +D+ +S    +I    
Sbjct: 121 AIICRGEKLSIAIMEGVFRAKGYPVTVINPVEKLLAQGHYLESTVDIAES--TLRIAAAA 178

Query: 157 IDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPK 215
           I +  I ++ GF  G D G  V LGR GSDYSA  L   L ++   I ++V+G++T DP+
Sbjct: 179 IPADHIVLMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPR 238

Query: 216 LVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRM-GTVI--S 272
            VP ARL+  +SY+EA+  +  G K +  +      + +I  L   T+N +  GT+I   
Sbjct: 239 TVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTSNPQAPGTLIGKD 298

Query: 273 NRTSRMPL--MTYKDGLLLINV 292
           +  + MP+  +T  + + +INV
Sbjct: 299 STDADMPVKGITNLNNMAMINV 320


>pir||DEECK thrA bifunctional enzyme - Escherichia coli
           >gi|537245|gb|AAA97301.1| (U14003) aspartokinase
           I-homoserine dehydrogenase I [Escherichia coli]
           >gi|1786183|gb|AAC73113.1| (AE000111) aspartokinase I,
           homoserine dehydrogenase I [Escherichia coli K12]
           Length = 820
           
 Score = 95.6 bits (234), Expect = 8e-19
 Identities = 85/289 (29%), Positives = 135/289 (46%), Gaps = 30/289 (10%)

Query: 4   MIVLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYA-KTFDSKYA 60
           M VLKFGG+SV N   F     + +S   + +VA V+SA   IT+ L+    KT   + A
Sbjct: 1   MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTISGQDA 60

Query: 61  I-KIADSYVKFART-----------------NGVDPNILS-PHIQELFNPPSLPKDALTD 101
           +  I+D+   FA                     VD       H+    +      D++  
Sbjct: 61  LPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIKHVLHGISLLGQCPDSINA 120

Query: 102 YILSIGELLSAVIFAEVVEGQ-----VIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEV 156
            ++  GE +S  I A V+E +     VI P E   A G + +  +D+ +S +  +I    
Sbjct: 121 ALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHYLESTVDIAESTR--RIAASR 178

Query: 157 IDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPK 215
           I +  + ++ GF  G + G  V LGR GSDYSA  L   L ++   I ++V+G++T DP+
Sbjct: 179 IPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPR 238

Query: 216 LVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNN 264
            VP ARL+  +SY+EA+  +  G K +  +      + +I  L   T N
Sbjct: 239 QVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGN 287


>sp|P00561|AK1H_ECOLI BIFUNCTIONAL ASPARTOKINASE/HOMOSERINE DEHYDROGENASE I (AKI-HDI)
           [INCLUDES: ASPARTOKINASE I ; HOMOSERINE DEHYDROGENASE I
           ]
           Length = 820
           
 Score = 94.8 bits (232), Expect = 1e-18
 Identities = 85/289 (29%), Positives = 134/289 (45%), Gaps = 30/289 (10%)

Query: 4   MIVLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYA-KTFDSKYA 60
           M VLKFGG+SV N   F     + +S   + +VA V+SA   IT+ L+    KT   + A
Sbjct: 1   MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTISGQDA 60

Query: 61  I-KIADSYVKFART-----------------NGVDPNILS-PHIQELFNPPSLPKDALTD 101
           +  I+D+   FA                     VD       H+    +      D++  
Sbjct: 61  LPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIKHVLHGISLLGQCPDSINA 120

Query: 102 YILSIGELLSAVIFAEVVEGQ-----VIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEV 156
            ++  GE +S  I A V+E +     VI P E   A G + +  +D+ +S +  +I    
Sbjct: 121 ALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHYLESTVDIAESTR--RIAASR 178

Query: 157 IDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPK 215
           I +  + ++ GF  G + G  V LGR GSDYSA  L   L ++   I ++V G++T DP+
Sbjct: 179 IPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVNGVYTCDPR 238

Query: 216 LVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNN 264
            VP ARL+  +SY+EA+  +  G K +  +      + +I  L   T N
Sbjct: 239 QVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGN 287


>sp|P41403|AK_MYCSM ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: ASPARTOKINASE ALPHA
           SUBUNIT (ASK-ALPHA); ASPARTOKINASE BETA SUBUNIT
           (ASK-BETA)] >gi|421602|pir||S31801 aspartate kinase (EC
           2.7.2.4) alpha chain - Mycobacterium smegmatis
           >gi|7434561|pir||S42422 aspartate kinase (EC 2.7.2.4)
           alpha chain - Mycobacterium smegmatis
           >gi|581352|emb|CAA78984.1| (Z17372) aspartokinase
           [Mycobacterium smegmatis]
           Length = 421
           
 Score = 94.4 bits (231), Expect = 2e-18
 Identities = 92/325 (28%), Positives = 146/325 (44%), Gaps = 64/325 (19%)

Query: 4   MIVLKFGGSSVKNDFHEAVSLTKSIFEEK----EVAVVVSALKGITDMLIKYAKTFDSKY 59
           ++V K+GGSSV  D      + + I E K    +V VVVSA+   TD L+  A+      
Sbjct: 3   LVVQKYGGSSVA-DAERIRRVAERIVETKKAGNDVVVVVSAMGDTTDDLLDLARQV---- 57

Query: 60  AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVV 119
                                         +P   P++   D +L+ GE +S  + A  +
Sbjct: 58  ------------------------------SPAPPPREM--DMLLTAGERISNALVAMAI 85

Query: 120 EGQVIYPWELF-SAYGKFGDGFIDLKKSKKNAKII-------YEVIDSGKIPIVPGFVGG 171
           E           S  G    G      +  NAKII        + +D G+I +V GF G 
Sbjct: 86  ESLGAQARSFTGSQAGVITTG------THGNAKIIDVTPGRLRDALDEGQIVLVAGFQGV 139

Query: 172 MDGYR--VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYE 229
               +   TLGRGGSD +AVA+   L++++  I ++V+GIFTADP++VP+AR +  +S+E
Sbjct: 140 SQDSKDVTTLGRGGSDTTAVAVAAALDADVCEIYTDVDGIFTADPRIVPNARHLDTVSFE 199

Query: 230 EALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDGLLL 289
           E L  A  G K +  +  E A+   + +    + + + GT++      +P+   +D +L 
Sbjct: 200 EMLEMAACGAKVLMLRCVEYARRYNVPIHVRSSYSDKPGTIVKGSIEDIPM---EDAILT 256

Query: 290 INVEEELEYRVIDEGPFWKLYDVPG 314
               +  E +V   G    L DVPG
Sbjct: 257 GVAHDRSEAKVTVVG----LPDVPG 277


>pir||E72715 probable aspartate kinase APE1140 - Aeropyrum pernix (strain K1)
           >gi|5104810|dbj|BAA80125.1| (AP000060) 473aa long
           hypothetical aspartate kinase [Aeropyrum pernix]
           Length = 473
           
 Score = 94.0 bits (230), Expect = 2e-18
 Identities = 78/261 (29%), Positives = 128/261 (48%), Gaps = 28/261 (10%)

Query: 4   MIVLKFGGSSVKND--FHEAVSLTKSIFEEK-EVAVVVSALKGITDMLIKYAKTFDSKYA 60
           ++V+KFGGS +     F  A  L   + E   E  VVVSA+KG+TD L+   +  D    
Sbjct: 27  LVVVKFGGSVLNGSPGFLAAGRLVLGLLESGLEPVVVVSAVKGVTDALLSSFERRDPGVG 86

Query: 61  IKIADSYVKFARTNGVDP------NILSPHIQELFNPPSLPKD---ALTDYILSIGELLS 111
             +  +Y+  AR  G+ P      ++ S  + +L     +       + D ++S GE LS
Sbjct: 87  GAVGKTYLSIARELGLPPESVRDVSLASAEVSKLLWAAEVLGQWTPRVRDLVVSYGERLS 146

Query: 112 AVIFAEV-----VEGQVIYPWEL-FSAYGKFGD-----GFIDLKKSKKNAKIIYEVIDSG 160
           A + A +     VE + +   E      G+FGD     G+ +    ++    +  +++ G
Sbjct: 147 AALMAGLLRRLGVEARWLGGGEAGIVTDGEFGDATPLYGYTEGVIRER----LEPMLEEG 202

Query: 161 KIPIVPGFVGGM-DGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPS 219
            +P+V GF G   +G    LGRGGSD +A  L   L +  V + ++V GI + DP++V  
Sbjct: 203 VVPVVAGFTGATREGDTTLLGRGGSDLTATLLASALGAGRVVLYTDVPGILSGDPRVVGE 262

Query: 220 ARLIPYLSYEEALIAAKHGMK 240
            R + Y+SYEEA   A+ G++
Sbjct: 263 PRRVGYMSYEEAWEVARLGLR 283


>emb|CAA23660.1| (V00361) thrA gene [EC 2.7.2.4 and EC 1.1.1.3] [Escherichia coli]
           >gi|147979|gb|AAA83914.1| (J01706) aspartokinase
           I-homoserine dehydrogenase I [Escherichia coli]
           >gi|216435|dbj|BAA01286.1| (D10483) aspartokinase I
           [Escherichia coli]
           Length = 820
           
 Score = 93.6 bits (229), Expect = 3e-18
 Identities = 84/289 (29%), Positives = 134/289 (46%), Gaps = 30/289 (10%)

Query: 4   MIVLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYA-KTFDSKYA 60
           M VLKFGG+S+ N   F     + +S   + +VA V+SA   IT+ L+    KT   + A
Sbjct: 1   MRVLKFGGTSLANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTISGQDA 60

Query: 61  I-KIADSYVKFART-----------------NGVDPNILS-PHIQELFNPPSLPKDALTD 101
           +  I+D+   FA                     VD       H+    +      D++  
Sbjct: 61  LPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIKHVLHGISLLGQCPDSINA 120

Query: 102 YILSIGELLSAVIFAEVVEGQ-----VIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEV 156
            ++  GE +S  I A V+E +     VI P E   A G + +  +D+ +S +  +I    
Sbjct: 121 ALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHYLESTVDIAESTR--RIAASR 178

Query: 157 IDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPK 215
           I +  + ++ GF  G + G  V LGR GSDYSA  L   L ++   I ++V G++T DP+
Sbjct: 179 IPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVNGVYTCDPR 238

Query: 216 LVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNN 264
            VP ARL+  +SY+EA+  +  G K +  +      + +I  L   T N
Sbjct: 239 QVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGN 287


>sp|P26512|AK_CORGL ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: ASPARTOKINASE ALPHA
           SUBUNIT; ASPARTOKINASE BETA SUBUNIT]
           >gi|320521|pir||S15276 aspartate kinase (EC 2.7.2.4)
           alpha chain - Corynebacterium glutamicum
           >gi|580983|emb|CAA40502.1| (X57226) aspartate kinase
           [Corynebacterium glutamicum]
           Length = 421
           
 Score = 93.2 bits (228), Expect = 4e-18
 Identities = 97/340 (28%), Positives = 159/340 (46%), Gaps = 69/340 (20%)

Query: 4   MIVLKFGGSSVKN-----DFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSK 58
           ++V K+GGSS+++     +  E +  TK      +V VVVSA+   TD L++ A      
Sbjct: 3   LVVQKYGGSSLESAERIRNVAERIVATKKA--GNDVVVVVSAMGDTTDELLELA------ 54

Query: 59  YAIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEV 118
                       A  N V P       +E+            D +L+ GE +S  + A  
Sbjct: 55  ------------AAVNPVPP------AREM------------DMLLTAGERISNALVAMA 84

Query: 119 VEGQVIYPWELFSAYGKFGDGFIDLKKSKK--NAKII-------YEVIDSGKIPIVPGFV 169
           +E        L +    F      +  +++  NA+I+        E +D GKI IV GF 
Sbjct: 85  IES-------LGAEAQSFTGSQAGVLTTERHGNARIVDVTPGRVREALDEGKICIVAGFQ 137

Query: 170 GGMDGYR--VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLS 227
           G     R   TLGRGGSD +AVAL   LN+++  I S+V+G++TADP++VP+A+ +  LS
Sbjct: 138 GVNKETRDVTTLGRGGSDTTAVALAAALNADVCEIYSDVDGVYTADPRIVPNAQKLEKLS 197

Query: 228 YEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDGL 287
           +EE L  A  G K +  ++ E A+   + +    + +   GT+I+     +P+   ++ +
Sbjct: 198 FEEMLELAAVGSKILVLRSVEYARAFNVPLRVRSSYSNDPGTLIAGSMEDIPV---EEAV 254

Query: 288 LLINVEEELEYRVIDEGPFWKLYDVPGNEGIRIIRELHKA 327
           L     ++ E +V   G    + D PG E  ++ R L  A
Sbjct: 255 LTGVATDKSEAKVTVLG----ISDKPG-EAAKVFRALADA 289


>gb|AAD49567.1|AF134837_1 (AF134837) aspartokinase subunit A [Amycolatopsis mediterranei]
           Length = 421
           
 Score = 91.3 bits (223), Expect = 2e-17
 Identities = 77/291 (26%), Positives = 128/291 (43%), Gaps = 57/291 (19%)

Query: 4   MIVLKFGGSSVKNDFH-----EAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSK 58
           ++V K+GGSS+++        E +  TK      +V VV SA+   TD L+  A+     
Sbjct: 3   LVVQKYGGSSLESADRIKRVAERIVATKKA--GNDVVVVCSAMGDTTDELLDLAQQV--- 57

Query: 59  YAIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEV 118
                                          NP   P +   D +L+ GE +S  + A  
Sbjct: 58  -------------------------------NPA--PPEREMDMLLTAGERISNSLVAMA 84

Query: 119 VEGQVIYPWELFSAYGKF-------GDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGG 171
           +  Q    W    +               ID+  S+     + E +D G I +V GF G 
Sbjct: 85  IAAQGAEAWSFTGSQAGVVTTSVHGNARIIDVTPSR-----VTEALDQGYIALVAGFQGV 139

Query: 172 MDGYR--VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYE 229
               +   TLGRGGSD +AVAL   LN+++  I S+V+G++TADP++VP A+ +  ++YE
Sbjct: 140 AQDTKDITTLGRGGSDTTAVALAAALNADVCEIYSDVDGVYTADPRVVPDAKKLDTVTYE 199

Query: 230 EALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPL 280
           E L  A  G K +  ++ E A+   + +    + + + GT ++     +P+
Sbjct: 200 EMLELAASGSKILHLRSVEYARRYGVPIRVRSSYSDKPGTTVTGSIEEIPV 250


>sp|P41398|AK_CORFL ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: ASPARTOKINASE ALPHA
           SUBUNIT; ASPARTOKINASE BETA SUBUNIT]
           >gi|289909|gb|AAA23293.1| (L16848) aspartokinase
           [Corynebacterium flavescens]
           Length = 421
           
 Score = 91.3 bits (223), Expect = 2e-17
 Identities = 96/340 (28%), Positives = 158/340 (46%), Gaps = 69/340 (20%)

Query: 4   MIVLKFGGSSVKN-----DFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSK 58
           ++V K+GGSS+++     +  E +  TK      +V VV SA+   TD L++ A      
Sbjct: 3   LVVQKYGGSSLESAERIRNVAERIVATKKA--GNDVVVVCSAMGDTTDELLELA------ 54

Query: 59  YAIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEV 118
                       A  N V P       +E+            D +L+ GE +S  + A  
Sbjct: 55  ------------AAVNPVPP------AREM------------DMLLTAGERISNALVAMA 84

Query: 119 VEGQVIYPWELFSAYGKFGDGFIDLKKSKK--NAKII-------YEVIDSGKIPIVPGFV 169
           +E        L +    F      +  +++  NA+I+        E +D GKI IV GF 
Sbjct: 85  IES-------LGAEAQSFTGSQAGVLTTERHGNARIVDVTPGRVREALDEGKICIVAGFQ 137

Query: 170 GGMDGYR--VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLS 227
           G     R   TLGRGGSD +AVAL   LN+++  I S+V+G++TADP++VP+A+ +  LS
Sbjct: 138 GVNKETRDVTTLGRGGSDTTAVALAAALNADVCEIYSDVDGVYTADPRIVPNAQKLEKLS 197

Query: 228 YEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDGL 287
           +EE L  A  G K +  ++ E A+   + +    + +   GT+I+     +P+   ++ +
Sbjct: 198 FEEMLELAAVGSKILVLRSVEYARAFNVPLRVRSSYSNDPGTLIAGSMEDIPV---EEAV 254

Query: 288 LLINVEEELEYRVIDEGPFWKLYDVPGNEGIRIIRELHKA 327
           L     ++ E +V   G    + D PG E  ++ R L  A
Sbjct: 255 LTGVATDKSEAKVTVLG----ISDKPG-EAAKVFRALADA 289


>sp|P53553|AK2_BACST ASPARTOKINASE 2 (ASPARTOKINASE II) (ASPARTATE KINASE 2) [CONTAINS:
           ASPARTOKINASE II ALPHA SUBUNIT; ASPARTOKINASE II BETA
           SUBUNIT] >gi|2126845|pir||JC4640 aspartate kinase (EC
           2.7.2.4) II - Bacillus stearothermophilus
           >gi|928811|gb|AAB06216.1| (L46351) aspartokinase II
           [Bacillus stearothermophilus]
           Length = 407
           
 Score = 89.3 bits (218), Expect = 6e-17
 Identities = 85/284 (29%), Positives = 127/284 (43%), Gaps = 52/284 (18%)

Query: 4   MIVLKFGGSSV---KNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
           +IV KFGG+SV   +   H A  + + + +  +V VVVSA+   TD L+  AK       
Sbjct: 3   IIVQKFGGTSVGSIERIQHVANRVIEEVQKGNDVVVVVSAMGKTTDELVNLAK------- 55

Query: 61  IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
                                     ++ N PS  +    D +LS GE +S  + A  + 
Sbjct: 56  --------------------------QISNHPSKRE---MDMLLSTGEQVSIALLAMSLH 86

Query: 121 GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKI-------IYEVIDSGKIPIVPGFVGGMD 173
            +    ++  S  G      I  ++   NA+I       I   +D G I IV GF G  +
Sbjct: 87  EK---GYKAVSLTG--WQAGITTEEMHGNARIMNIDTTRIRRCLDEGAIVIVAGFQGVTE 141

Query: 174 -GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEAL 232
            G   TLGRGGSD +AVAL   L +E   I ++V G+FT DP+ V +AR I  +SY+E L
Sbjct: 142 TGEITTLGRGGSDTTAVALAAALKAEKCDIYTDVTGVFTTDPRYVKTARKIKEISYDEML 201

Query: 233 IAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTS 276
             A  G   +  +A E AK  ++ +    +     GT++    S
Sbjct: 202 ELANLGAGVLHPRAVEFAKNYEVPLEVRSSMENERGTMVKEEVS 245


>sp|Q59229|AK2_BACSP ASPARTOKINASE 2 (ASPARTOKINASE II) (ASPARTATE KINASE 2) [CONTAINS:
           ASPARTOKINASE II ALPHA SUBUNIT; ASPARTOKINASE II BETA
           SUBUNIT] >gi|1075793|pir||A48946 aspartate kinase (EC
           2.7.2.4) II precursor - Bacillus sp.  (strain MGA3)
           >gi|142540|gb|AAA22251.1| (M93419) aspartokinase II
           [Bacillus sp.]
           Length = 411
           
 Score = 88.9 bits (217), Expect = 8e-17
 Identities = 85/284 (29%), Positives = 125/284 (43%), Gaps = 52/284 (18%)

Query: 4   MIVLKFGGSSVKNDFHEAVSLTKSIFEEK----EVAVVVSALKGITDMLIKYAKTFDSKY 59
           +IV KFGG+SV       +++   + EEK    +V VVVSA+   TD L+  AK   +  
Sbjct: 3   LIVQKFGGTSV-GSVERILNVANRVIEEKKNGNDVVVVVSAMGKTTDELVDLAKQISA-- 59

Query: 60  AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGE-----LLSAVI 114
                                         +PP    D L    L+ GE     LL+  +
Sbjct: 60  ------------------------------HPPKREMDML----LTTGEQVTISLLAMAL 85

Query: 115 FAEVVEGQVIYPWEL-FSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVG-GM 172
             +  E      W+   +    FG+  I   +++K    I + ++ GKI +V GF G   
Sbjct: 86  NEKGYEAISYTGWQAGITTEPVFGNARILNIETEK----IQKQLNEGKIVVVAGFQGIDE 141

Query: 173 DGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEAL 232
            G   TLGRGGSD +AVAL   L +E   I ++V G+FT DP+ V SAR +  +SY+E L
Sbjct: 142 HGEITTLGRGGSDTTAVALAAALKAEKCDIYTDVTGVFTTDPRYVKSARKLASISYDEML 201

Query: 233 IAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTS 276
             A  G   +  +A E AK   I +    +     GT+I    +
Sbjct: 202 ELANLGAGVLHPRAVEFAKNYGITLEVRSSMEREEGTIIEEEVT 245


>sp|Q9ZCI7|AK_RICPR ASPARTOKINASE (ASPARTATE KINASE) >gi|7434558|pir||E71635
           aspartokinase (lysC) RP753 - Rickettsia prowazekii
           >gi|3861282|emb|CAA15181.1| (AJ235273) ASPARTOKINASE
           (lysC) [Rickettsia prowazekii]
           Length = 446
           
 Score = 88.9 bits (217), Expect = 8e-17
 Identities = 82/269 (30%), Positives = 124/269 (45%), Gaps = 57/269 (21%)

Query: 4   MIVLKFGGSSVKN--DFHEAVSLTKS-IFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
           +I+ KFGG+SV N     + V + K+ I +  +V VVVSA+ G+T+ L+       S   
Sbjct: 3   LIIQKFGGTSVANVERIKKLVPIIKAEIAKNNQVIVVVSAMAGVTNQLVTLCNEVSS--- 59

Query: 61  IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFA---- 116
               +   +FA                             D  LS GE+++A + A    
Sbjct: 60  ---LNKRSQFAEY---------------------------DVALSSGEIVTASLLALALQ 89

Query: 117 -EVVEGQVIYPWEL----FSAYGKFGDGFI--DLKKSKKNAKIIYEVIDSGKIPIVPGFV 169
            E ++ Q +  W+L     + Y K    FI  DL +     KII         PI+ GF 
Sbjct: 90  EEEIKAQSLLAWQLPIRTNNNYSKALVEFITTDLLEKYLQLKII---------PIIAGFQ 140

Query: 170 GGMDGYRVT-LGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSY 228
           G     RVT LGRGGSD +A  +   + ++   I ++V+GIFTADP+++P+A+ I  + +
Sbjct: 141 GINKSNRVTTLGRGGSDTTAALIAAAMKADRCDIYTDVDGIFTADPRIIPNAKRIKEIDF 200

Query: 229 EEALIAAKHGMKAIQWKAAELAKEKKILM 257
            E L  A  G K +  +A EL    KI M
Sbjct: 201 LEMLELASSGAKVLHPRAVELVMRYKIDM 229


>pir||H82086 aspartokinase I/homoserine dehydrogenase, threonine-sensitive
           VC2364 [imported] - Vibrio cholerae  (group O1 strain
           N16961) >gi|9656933|gb|AAF95507.1| (AE004306)
           aspartokinase I/homoserine dehydrogenase,
           threonine-sensitive [Vibrio cholerae]
           Length = 825
           
 Score = 88.5 bits (216), Expect = 1e-16
 Identities = 87/324 (26%), Positives = 151/324 (45%), Gaps = 39/324 (12%)

Query: 4   MIVLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSK--- 58
           M VLKFGGSS+ +   F  A  +  +  +++EVAVV+SA    T+ L+   ++   +   
Sbjct: 7   MRVLKFGGSSLADPERFLRAADIIANNAQQEEVAVVLSAPGKTTNKLVAVIESALRQGEV 66

Query: 59  --YAIKIADSYVKFARTNGVD---PNILSPHIQELFNPP--------------SLPKDAL 99
               +++  S+  +A  +G+    PN+     Q+  +                 +  D +
Sbjct: 67  EAQIVELESSF--YALLDGIKAQLPNLDDSAYQQQVHSSMTQLRQFVHGITLLGMCPDNV 124

Query: 100 TDYILSIGE-----LLSAVIFAEVVEGQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIY 154
              I+S GE     L+ AV+ A+ +   ++ P +   A G   +  +D++ S +  +   
Sbjct: 125 NARIISKGERVSIQLMKAVMEAKGLPANLVDPVKYLLAKGDHLEAMVDVEISTQRFR--Q 182

Query: 155 EVIDSGKIPIVPGFVGG-MDGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTAD 213
             +    + I+PGF  G   G  V LGR GSDYSA  L   L ++   I ++V+G++  D
Sbjct: 183 APLPQQHVNIMPGFTAGNAQGELVCLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYNCD 242

Query: 214 PKLVPSARLIPYLSYEEALIAAKHGMKAIQWKA-AELAKEKKILMLFGRTNNWRMGTVIS 272
           P+LV  ARL+  LSY+EA+  +  G   +  K  A +A+ +   ++    N    GT+I 
Sbjct: 243 PRLVDDARLLKSLSYQEAMELSYFGASVLHPKTIAPIAQFQIPCLIKNSFNPQGAGTLIG 302

Query: 273 NRTSRMPL----MTYKDGLLLINV 292
             T    L    +T    L ++NV
Sbjct: 303 QDTGEDKLAIKGITTLSNLTMVNV 326


>pir||T35383 probable aspartokinase - Streptomyces coelicolor
           >gi|5123890|emb|CAB45482.1| (AL079348) putative
           aspartokinase [Streptomyces coelicolor A3(2)]
           Length = 425
           
 Score = 88.5 bits (216), Expect = 1e-16
 Identities = 83/283 (29%), Positives = 127/283 (44%), Gaps = 55/283 (19%)

Query: 4   MIVLKFGGSSVKNDFHEAVSLTKSIFEEK----EVAVVVSALKGITDMLIKYAKTFDSKY 59
           ++V K+GGSSV  D      + K I E K    +V  VVSA+   TD LI  A+      
Sbjct: 3   LVVQKYGGSSVA-DAEGIKRVAKRIVEAKKNGNQVVAVVSAMGDTTDELIDLAEQ----- 56

Query: 60  AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVV 119
                                +SP          +P     D +L+ GE +S  + A  +
Sbjct: 57  ---------------------VSP----------IPAGRELDMLLTAGERISMALLAMAI 85

Query: 120 EGQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEV-------IDSGKIPIVPGFVGGM 172
           +       E  S  G       D   +K  A+II          +D G + IV GF G  
Sbjct: 86  KN---LGHEAQSFTGSQAGVITDSVHNK--ARIIDVTPGRIRTSVDEGNVAIVAGFQGVS 140

Query: 173 DGYR--VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEE 230
              +   TLGRGGSD +AVAL   L++++  I ++V+G+FTADP++VP A+ I ++S+E+
Sbjct: 141 QDSKDITTLGRGGSDTTAVALAAALDADVCEIYTDVDGVFTADPRVVPKAKKIDWISFED 200

Query: 231 ALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISN 273
            L  A  G K +  +  E A+   I +    + +   GT +S+
Sbjct: 201 MLELAASGSKVLLHRCVEYARRYNIPIHVRSSFSGLQGTWVSS 243


>sp|O67221|AK_AQUAE ASPARTOKINASE (ASPARTATE KINASE) >gi|7434554|pir||B70399
           aspartokinase - Aquifex aeolicus
           >gi|2983613|gb|AAC07182.1| (AE000726) aspartokinase
           [Aquifex aeolicus]
           Length = 415
           
 Score = 88.5 bits (216), Expect = 1e-16
 Identities = 84/280 (30%), Positives = 130/280 (46%), Gaps = 53/280 (18%)

Query: 3   KMIVLKFGGSSVKNDFHEAVSLT-----KSIFEEKEVAVVVSALKGITDMLIKYAKTFDS 57
           K++V KFGG+SV     E + L      K++ +  +  VV SA+ G TD LI+ AK    
Sbjct: 2   KILVQKFGGTSVGT--LERIELCAKRVIKALEKGYKPVVVSSAMAGETDSLIELAKKVHP 59

Query: 58  KYAIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAE 117
           +                                    P +   D +L++GE  +  +FA 
Sbjct: 60  R------------------------------------PPEREMDTLLAVGEQKAIALFAM 83

Query: 118 VVEGQVIYPWELFSAYGKFGDGFIDLKKSKKNAKII-----YEVIDSGKIPIVPGFVGGM 172
            +  ++ YP    S  G       D   +K   + I       +I+ G IP+V GF G  
Sbjct: 84  TLN-KLGYP--AVSLCGWQVPIITDNVHTKARIRKIGISRLLSLIEEGYIPVVAGFQGVT 140

Query: 173 DGYRVT-LGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEA 231
           + + +T LGRGGSD +AVAL   L ++   I ++V G+FTADP++VP+A+ I  +SYEE 
Sbjct: 141 EDWEITTLGRGGSDTTAVALAAALKADC-EINTDVPGVFTADPRIVPNAKKIKKISYEEM 199

Query: 232 LIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVI 271
           L  A  G K +Q ++ E A +  + +    T +   GT I
Sbjct: 200 LELASLGAKVMQIRSVEFAAKYNVRIHVRSTFSEEEGTWI 239


>gb|AAD41796.1| (AF135862) precursor monofunctional aspartokinase [Glycine max]
           Length = 564
           
 Score = 88.5 bits (216), Expect = 1e-16
 Identities = 80/280 (28%), Positives = 134/280 (47%), Gaps = 35/280 (12%)

Query: 6   VLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYAIKI 63
           V+KFGGSSV +     E  +L  S  EE+ + VV+SA+   T+ L+   +   S   I +
Sbjct: 87  VMKFGGSSVASADRMKEVATLILSFPEERPI-VVLSAMGKTTNKLLLAGEKAVSCGVINV 145

Query: 64  A---------DSYVKFARTNGVDPNILSPHIQEL---FNPPSLPKDALT---DYILSIGE 108
           +         D +++     GVD +++S H++EL       ++ K+      DY++S GE
Sbjct: 146 SSIEELCFIKDLHLRTVDQLGVDGSVISKHLEELEQLLKGIAMMKELTKRTQDYLVSFGE 205

Query: 109 LLSAVIFAEVVEGQVIYPWELFSAYGKFGDGFI--------DLKKSKKNA---KIIYEVI 157
            +S  IFA  +    +   +    Y  F  GFI        D+ ++   A   ++  + +
Sbjct: 206 CMSTRIFAAYLNKIGVKARQ----YDAFEIGFITTDDFTNADILEATYPAVAKRLHGDWL 261

Query: 158 DSGKIPIVPGFVGGM--DGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPK 215
               I IV GF+G         TLGRGGSD +A  +G  L    + +  +V+G+ T DP 
Sbjct: 262 SDPAIAIVTGFLGKARKSCAVTTLGRGGSDLTATTIGKALGLPEIQVWKDVDGVLTCDPN 321

Query: 216 LVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKI 255
           + P A  +PYL+++EA   A  G + +  ++   A+E  I
Sbjct: 322 IYPKAEPVPYLTFDEAAELAYFGAQVLHPQSMRPARESDI 361


>emb|CAA99580.1| (Z75208) aspartokinase II alpha subunit [Bacillus subtilis]
           >gi|2635312|emb|CAB14807.1| (Z99118) aspartokinase II
           alpha subunit (aa 1->408) and beta subunit (aa 246->408)
           [Bacillus subtilis]
           Length = 408
           
 Score = 88.2 bits (215), Expect = 1e-16
 Identities = 80/277 (28%), Positives = 128/277 (45%), Gaps = 38/277 (13%)

Query: 4   MIVLKFGGSSVKNDFHEAVSLTKSIFEEK---EVAVVVSALKGITDMLIKYAKTFDSKYA 60
           +IV KFGG+SV +      +  ++I E++   +V VVVSA+   TD L+  AK    + +
Sbjct: 3   LIVQKFGGTSVGSVEKIQNAANRAIAEKQKGHQVVVVVSAMGKSTDELVSLAKAISDQPS 62

Query: 61  IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
            +  D  +  A    V  ++LS  +QE             D +   G    A I  E + 
Sbjct: 63  KREMDMLL--ATGEQVTISLLSMALQEKGY----------DAVSYTG--WQAGIRTEAIH 108

Query: 121 GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMDGYRVT-L 179
           G                      + +  +  ++ + ++ GKI IV GF G  +   +T L
Sbjct: 109 GNA--------------------RITDIDTSVLADQLEKGKIVIVAGFQGMTEDCEITTL 148

Query: 180 GRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAKHGM 239
           GRGGSD +AVAL   L ++   I ++V G+FT DP+ V SAR +  +SY+E L  A  G 
Sbjct: 149 GRGGSDTTAVALAAALKADKCDIYTDVPGVFTTDPRYVKSARKLEGISYDEMLELANLGA 208

Query: 240 KAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTS 276
             +  +A E AK  ++ +    +     GT+I   +S
Sbjct: 209 GVLHPRAVEFAKNYQVPLEVRSSTETEAGTLIEEESS 245


>pir||F82328 aspartokinase III, lysine-sensitive VC0391 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9654811|gb|AAF93564.1| (AE004127) aspartokinase III,
           lysine-sensitive [Vibrio cholerae]
           Length = 479
           
 Score = 87.8 bits (214), Expect = 2e-16
 Identities = 75/259 (28%), Positives = 127/259 (48%), Gaps = 26/259 (10%)

Query: 6   VLKFGGSSVKNDFHEAVSLTKSIFEEKEVA--VVVSALKGITDMLIKYAK---TFDSKYA 60
           V KFGG+SV N   EA+S   +I E       VV SA  G+T++L++ A    + + + A
Sbjct: 34  VAKFGGTSVAN--FEAMSRCSAIIENNPQTRLVVSSACSGVTNLLVELANGVASTERRQA 91

Query: 61  I--KIAD-SYVKFARTNGVDPNILSPHIQELFNPPSLPKDA--------LTDYILSIGEL 109
           I  ++AD  YV   +    DP  +   ++ + +  +   +A        LTD++++ GEL
Sbjct: 92  ILQQLADIHYVIIDQL--ADPTRVEKEVKAVLDSVASAAEAASFQSSKKLTDHLVACGEL 149

Query: 110 LSAVIFAEVVEGQVIYPW-----ELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPI 164
           +S  I  +++  + +        E+      +G     LK+  + AK     +    + +
Sbjct: 150 ISTYILTQLMRERGVDAVRFDIREVLRTDDHYGRAEPQLKEIAQLAKEKLVPLCEQYVVV 209

Query: 165 VPGFVGG-MDGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLI 223
             GF+G    G   TLGRGGSDYSA  +   + +  + I ++V GI++ DP++ P A  I
Sbjct: 210 TQGFIGSDAQGNTTTLGRGGSDYSAALIAEAVQASGLEIWTDVPGIYSTDPRIAPKAAPI 269

Query: 224 PYLSYEEALIAAKHGMKAI 242
           P +S+ EA   A  G K +
Sbjct: 270 PEISFSEASEMANFGAKIL 288


>pir||B69207 aspartokinase II alpha subunit - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2621892|gb|AAB85302.1| (AE000858) aspartokinase II
           alpha subunit [Methanobacterium thermoautotrophicum]
           Length = 406
           
 Score = 87.4 bits (213), Expect = 2e-16
 Identities = 69/253 (27%), Positives = 122/253 (47%), Gaps = 49/253 (19%)

Query: 3   KMIVLKFGGSSVKNDFH---EAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKY 59
           ++IV KFGG+S+ N       A S+ K   + ++V VVVSA+   TD L++         
Sbjct: 2   ELIVAKFGGTSIGNGRRIKKAARSVVKEYMKGRKVVVVVSAINKTTDELLQ--------- 52

Query: 60  AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVV 119
                               I+   +++      L +      I+S+GE+ S  IF+  +
Sbjct: 53  --------------------IVDEAMEDAVTEKQLAE------IVSMGEMTSVRIFSSAI 86

Query: 120 EG-----QVIYP----WELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVG 170
           E      + I P    W + +      +  +D + +++ ++ + +++D G IP+V GF+G
Sbjct: 87  EALGVKSEYIDPFMDEWPIITDSNLL-NAKVDFEATEEKSRELLKLLDQGIIPVVCGFLG 145

Query: 171 -GMDGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYE 229
              +GY  TLGRGGSD +A  LG  L ++ V I+++V G+ + DP  +  A+ +  +S E
Sbjct: 146 RDPNGYITTLGRGGSDITAFLLGHCLKADEVIIVTDVGGVMSTDPNKLQGAKKLDKISVE 205

Query: 230 EALIAAKHGMKAI 242
           E    A HG + +
Sbjct: 206 EMRDLATHGAQVL 218


>pir||T48575 aspartate kinase - Arabidopsis thaliana >gi|7529283|emb|CAB86635.1|
           (AL163491) aspartate kinase [Arabidopsis thaliana]
           Length = 569
           
 Score = 87.4 bits (213), Expect = 2e-16
 Identities = 80/293 (27%), Positives = 140/293 (47%), Gaps = 26/293 (8%)

Query: 6   VLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYAIK- 62
           V+KFGGSSV +     E   L  +  EE  V V+ +  K   ++L+   K      +   
Sbjct: 89  VMKFGGSSVASAERMKEVADLILTFPEESPVIVLSAMGKTTNNLLLAGEKAVSCGVSNAS 148

Query: 63  -------IADSYVKFARTNGVDPNILSPHIQEL---FNPPSLPKDALT---DYILSIGEL 109
                  I + +++  +   +DP+++  +++EL       ++ K+      DY++S GE 
Sbjct: 149 EIEELSIIKELHIRTVKELNIDPSVILTYLEELEQLLKGIAMMKELTLRTRDYLVSFGEC 208

Query: 110 LSAVIFAEV-----VEGQVIYPWEL-FSAYGKFGDGFIDLKKSKKNAKIIYEV-IDSGKI 162
           LS  IFA       V+ +    +E+ F     F +G I        AK +Y+  +    +
Sbjct: 209 LSTRIFAAYLNTIGVKARQYDAFEIGFITTDDFTNGDILEATYPAVAKRLYDDWMHDPAV 268

Query: 163 PIVPGFVGG--MDGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSA 220
           PIV GF+G     G   TLGRGGSD +A  +G  L  + + +  +V+G+ T DP +   A
Sbjct: 269 PIVTGFLGKGWKTGAVTTLGRGGSDLTATTIGKALGLKEIQVWKDVDGVLTCDPTIYKRA 328

Query: 221 RLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRM-GTVIS 272
             +PYL+++EA   A  G + +  ++   A+E +I +    + N +  GT+I+
Sbjct: 329 TPVPYLTFDEAAELAYFGAQVLHPQSMRPAREGEIPVRVKNSYNPKAPGTIIT 381


>dbj|BAB08285.1| (AB007650) lysine-sensitive aspartate kinase [Arabidopsis thaliana]
           Length = 544
           
 Score = 87.4 bits (213), Expect = 2e-16
 Identities = 77/296 (26%), Positives = 143/296 (48%), Gaps = 32/296 (10%)

Query: 6   VLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAK--------TF 55
           V+KFGGSSV++     E  +L  S  +E+ V +V+SA+   T+ L+K  +          
Sbjct: 85  VMKFGGSSVESAERMKEVANLILSFPDERPV-IVLSAMGKTTNKLLKAGEKAVTCGVTNV 143

Query: 56  DSKYAIK-IADSYVKFARTNGVDPNILSPHIQ---ELFNPPSLPKDALT---DYILSIGE 108
           +S   +  I + +++ A   GV+  ++  H++   +L    S+ K+      DY++S GE
Sbjct: 144 ESIEELSFIKELHLRTAHELGVETTVIEKHLEGLHQLLKGISMMKELTLRTRDYLVSFGE 203

Query: 109 LLSAVIFAEVVE--GQVIYPWELFSAYGKFGDGF-----IDLKKSKKNAKIIYEVIDSGK 161
            +S  +F+  +   G     ++ F       D F     ++      +  ++ +      
Sbjct: 204 CMSTRLFSAYLNKIGHKARQYDAFEIGFITTDDFTNADILEATYPAVSKTLVGDWSKENA 263

Query: 162 IPIVPGFVGGMDGYR----VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLV 217
           +P+V G++G   G+R     TLGRGGSD +A  +G  L    + +  +V+G+ T DP + 
Sbjct: 264 VPVVTGYLG--KGWRSCAITTLGRGGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIY 321

Query: 218 PSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKI-LMLFGRTNNWRMGTVIS 272
           P A+ +PYL+++EA   A  G + +   +   A++  I + +    N    GTVI+
Sbjct: 322 PGAQSVPYLTFDEAAELAYFGAQVLHPLSMRPARDGDIPVRVKNSYNPTAPGTVIT 377


>pir||H81865 aspartate kinase (EC 2.7.2.4) NMA1701 [imported] - Neisseria
           meningitidis (group A strain Z2491)
           >gi|7380342|emb|CAB84929.1| (AL162756) aspartate kinase
           [Neisseria meningitidis Z2491]
           Length = 405
           
 Score = 87.4 bits (213), Expect = 2e-16
 Identities = 81/283 (28%), Positives = 136/283 (47%), Gaps = 57/283 (20%)

Query: 4   MIVLKFGGSSVKNDF---HEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
           +IV K+GG+SV +     + A  + K+  E  ++ VVVSA+ G T+ L+           
Sbjct: 3   LIVHKYGGTSVGSPERIKNVAKRVAKARAEGHDIVVVVSAMSGETNRLVA---------- 52

Query: 61  IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEV-- 118
                               L+  +QE  +P  L      D +LS GE ++  + A    
Sbjct: 53  --------------------LAHEMQEHPDPREL------DVVLSTGEQVTIGLLAMALK 86

Query: 119 ---VEGQVIYPWELF----SAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVG- 170
              V+ +    W++     +A+ K     ID +K + +       + +GK+ IV GF G 
Sbjct: 87  DIGVDAKSYTGWQVALKTDTAHTKARIESIDDEKMRAD-------LTAGKVVIVAGFQGI 139

Query: 171 GMDGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEE 230
             +G   TLGRGGSD SAVAL   L ++   I ++V+G++T DP++VP AR +  +++EE
Sbjct: 140 SSEGDISTLGRGGSDTSAVALAAALKADECQIYTDVDGVYTTDPRVVPEARRMDTVTFEE 199

Query: 231 ALIAAKHGMKAIQWKAAELAKEKKI-LMLFGRTNNWRMGTVIS 272
            +  A  G K +Q ++ E A + K+ L +     +   GT+I+
Sbjct: 200 MIELASLGSKVLQIRSVEFAGKYKVRLRVLSSLQDGGNGTLIT 242


>sp|P77991|AK_THEFL ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: ASPARTOKINASE ALPHA
           SUBUNIT (ASK-ALPHA); ASPARTOKINASE BETA SUBUNIT
           (ASK-BETA)] >gi|1616997|dbj|BAA07146.1| (D37928)
           aspartokinase alpha-2 [Thermus aquaticus]
           Length = 405
           
 Score = 87.4 bits (213), Expect = 2e-16
 Identities = 75/282 (26%), Positives = 127/282 (44%), Gaps = 44/282 (15%)

Query: 4   MIVLKFGGSSVKNDFHEAVSLTKSIFEEKE----VAVVVSALKGITDMLIKYAKTFDSKY 59
           ++V K+GG+SV  D      + + I   +E    +AVVVSA+   TD LI  AK  + + 
Sbjct: 3   LVVQKYGGTSV-GDLERIHKVAQRIAHYREKGHRLAVVVSAMGHTTDELIALAKRVNPR- 60

Query: 60  AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIG-ELLSAVIFAEV 118
                                          PP    D LT     +   LLS  ++A  
Sbjct: 61  -------------------------------PPFRELDLLTTTGEQVSVALLSMQLWAMG 89

Query: 119 VEGQVIYPWEL-FSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGM-DGYR 176
           +  +     ++  +  G++GD  I     + N   I E +D G + ++ GF+G   +G  
Sbjct: 90  IPAKGFVQHQIGITTDGRYGDARI----LEVNPARIREALDQGFVAVIAGFMGTTPEGEI 145

Query: 177 VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAK 236
            TLGRGGSD +AVA+   L ++   I ++ EG++T DP L+P AR +  + Y++ L  A 
Sbjct: 146 TTLGRGGSDTTAVAIAAALGAKECEIYTDTEGVYTTDPHLIPEARKLSVIGYDQMLEMAA 205

Query: 237 HGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRM 278
            G + +  +A   AK   +++    + ++  GT++      M
Sbjct: 206 LGARVLHPRAVYYAKRYGVVLHVRSSFSYNPGTLVKEVAMEM 247


>emb|CAA67376.1| (X98873) aspartate kinase [Arabidopsis thaliana]
           Length = 569
           
 Score = 87.0 bits (212), Expect = 3e-16
 Identities = 80/293 (27%), Positives = 140/293 (47%), Gaps = 26/293 (8%)

Query: 6   VLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYAIK- 62
           V+KFGGSSV +     E   L  +  EE  V V+ +  K   ++L+   K      +   
Sbjct: 89  VMKFGGSSVASAERMKEVADLILTFPEESPVIVLSAMGKTTNNLLLAGEKAVSCGVSNAS 148

Query: 63  -------IADSYVKFARTNGVDPNILSPHIQEL---FNPPSLPKDALT---DYILSIGEL 109
                  I + +++  +   +DP+++  +++EL       ++ K+      DY++S GE 
Sbjct: 149 EIEELSIIKELHIRTVKELNIDPSVILTYLEELEQLLKGIAMMKELTLRTRDYLVSFGEC 208

Query: 110 LSAVIFAEV-----VEGQVIYPWEL-FSAYGKFGDGFIDLKKSKKNAKIIYEV-IDSGKI 162
           LS  IFA       V+ +    +E+ F     F +G I        AK +Y+  +    +
Sbjct: 209 LSTRIFAAYLNTIGVKARQYDAFEIGFITTDDFTNGDILEATYPAVAKRLYDDWMHDPAV 268

Query: 163 PIVPGFVGG--MDGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSA 220
           PIV GF+G     G   TLGRGGSD +A  +G  L  + + +  +V+G+ T DP +   A
Sbjct: 269 PIVTGFLGKGWKTGAVTTLGRGGSDLTATTIGKALGLKEIQVWKDVDGVLTCDPTIYKRA 328

Query: 221 RLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRM-GTVIS 272
             +PYL+++EA   A  G + +  ++   A+E +I +    + N +  GT+I+
Sbjct: 329 TPVPYLTFDEAAELAYFGAQVLHPQSMRPAREGEIPVRVKSSYNPKAPGTIIT 381


>sp|P08495|AK2_BACSU ASPARTOKINASE 2 (ASPARTOKINASE II) (ASPARTATE KINASE 2) [CONTAINS:
           ASPARTOKINASE II ALPHA SUBUNIT; ASPARTOKINASE II BETA
           SUBUNIT] >gi|80248|pir||A29314 aspartate kinase (EC
           2.7.2.4) II precursor - Bacillus subtilis
           >gi|142523|gb|AAA87318.1| (J03294) aspartokinase II
           alpha subunit [Bacillus subtilis]
           Length = 408
           
 Score = 87.0 bits (212), Expect = 3e-16
 Identities = 80/277 (28%), Positives = 127/277 (44%), Gaps = 38/277 (13%)

Query: 4   MIVLKFGGSSVKNDFHEAVSLTKSIFEEK---EVAVVVSALKGITDMLIKYAKTFDSKYA 60
           +IV KFGG+SV +      +  ++I E++   +V VVVSA+   TD L+  AK    + +
Sbjct: 3   LIVQKFGGTSVGSVEKIQNAANRAIAEKQKGHQVVVVVSAMGKSTDELVSLAKAISDQPS 62

Query: 61  IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
            +  D  +  A    V  ++LS  +QE             D +   G    A I  E + 
Sbjct: 63  KREMDMLL--ATGEQVTISLLSMALQEKGY----------DAVSYTG--WQAGIRTEAIH 108

Query: 121 GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMDGYRVT-L 179
           G                      + +  +  ++ + ++ GKI IV GF G  +   +T L
Sbjct: 109 GNA--------------------RITDIDTSVLADQLEKGKIVIVAGFQGMTEDCEITTL 148

Query: 180 GRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAKHGM 239
           GRGGSD +AVAL   L  +   I ++V G+FT DP+ V SAR +  +SY+E L  A  G 
Sbjct: 149 GRGGSDTTAVALAAALKVDKCDIYTDVPGVFTTDPRYVKSARKLEGISYDEMLELANLGA 208

Query: 240 KAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTS 276
             +  +A E AK  ++ +    +     GT+I   +S
Sbjct: 209 GVLHPRAVEFAKNYQVPLEVRSSTETEAGTLIEEESS 245


>pir||A82311 aspartokinase, alpha and beta chains VC0547 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9654975|gb|AAF93715.1| (AE004140) aspartokinase,
           alpha and beta subunits [Vibrio cholerae]
           Length = 395
           
 Score = 86.2 bits (210), Expect = 5e-16
 Identities = 85/303 (28%), Positives = 133/303 (43%), Gaps = 46/303 (15%)

Query: 2   RKMIVLKFGGSSVKNDFHEAVSLTKSIFEEK----EVAVVVSALKGITDMLIKYAKTFDS 57
           + +IV KFGG+SV        ++ + I + K    +V VVVSA+ G T+ L+  A+  DS
Sbjct: 3   KPLIVQKFGGTSV-GSIERMQTVAEHIIKAKNDGNQVVVVVSAMAGETNRLVGLAQQVDS 61

Query: 58  KYAIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAE 117
                                    P+ +EL            D +LS GE +S  + A 
Sbjct: 62  V------------------------PNAREL------------DVLLSAGEQVSMALVAM 85

Query: 118 VVEGQVIYPWELFSAYGKF--GDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVG-GMDG 174
            +         L  A       +   D      + + I E+++   I IV GF G   +G
Sbjct: 86  TLHKMGYAARSLTGAQANIVTDNQHNDATIKHIDTRTITELLEQDFIVIVAGFQGINENG 145

Query: 175 YRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIA 234
              TLGRGGSD SAVAL   LN++   I ++V+GI+T DP++VPSAR +  + +      
Sbjct: 146 DITTLGRGGSDTSAVALAGALNADECQIFTDVDGIYTCDPRIVPSARKLDVIDFPSMEEM 205

Query: 235 AKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVI--SNRTSRMPLMTYKDGLLLINV 292
           A+ G K +     + A +  + +    T     G++I  S  T  +  +  +  + LI V
Sbjct: 206 ARKGAKVLHLPCVQYAWKHAVPLRVLSTFEVNQGSLIKGSAATHAVCGIALQRDMALIRV 265

Query: 293 EEE 295
           E E
Sbjct: 266 ESE 268


>pir||F81076 aspartokinase, alpha and beta chains NMB1498 [imported] - Neisseria
           meningitidis (group B strain MD58)
           >gi|7226740|gb|AAF41854.1| (AE002499) aspartokinase,
           alpha and beta subunits [Neisseria meningitidis MC58]
           Length = 405
           
 Score = 86.2 bits (210), Expect = 5e-16
 Identities = 80/278 (28%), Positives = 135/278 (47%), Gaps = 47/278 (16%)

Query: 4   MIVLKFGGSSVKNDF---HEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
           +IV K+GG+SV +     + A  + K+  E  ++ VVVSA+ G T+ L+           
Sbjct: 3   LIVHKYGGTSVGSPERIKNVAKRVAKARAEGHDIVVVVSAMSGETNRLVA---------- 52

Query: 61  IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
                               L+  +QE  +P  L     T   ++IG LL+  +    V+
Sbjct: 53  --------------------LAHEMQEHPDPRELDVVLATGEQVTIG-LLAMALKDIGVD 91

Query: 121 GQVIYPWELF----SAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVG-GMDGY 175
            +    W++     +A+ K     ID +K + +       + +GK+ IV GF G   +G 
Sbjct: 92  AKSYTGWQVALKTDTAHTKARIESIDDEKMRAD-------LTAGKVVIVAGFQGISSEGD 144

Query: 176 RVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAA 235
             TLGRGGSD SAVAL   L ++   I ++V+G++T DP++VP AR +  +++EE +  A
Sbjct: 145 ISTLGRGGSDTSAVALAAALKADECQIYTDVDGVYTTDPRVVPEARRMDTVTFEEMIELA 204

Query: 236 KHGMKAIQWKAAELAKEKKI-LMLFGRTNNWRMGTVIS 272
             G K +Q ++ E A + K+ L +     +   GT+I+
Sbjct: 205 SLGSKVLQIRSVEFAGKYKVRLRVLSSLQDGGNGTLIT 242


>sp|P97151|AK_THETH ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: ASPARTOKINASE ALPHA
           SUBUNIT (ASK-ALPHA); ASPARTOKINASE BETA SUBUNIT
           (ASK-BETA)] >gi|3088363|dbj|BAA25848.1| (AB013131)
           aspartate kinase alpha subunit [Thermus thermophilus]
           Length = 405
           
 Score = 85.8 bits (209), Expect = 7e-16
 Identities = 74/282 (26%), Positives = 127/282 (44%), Gaps = 44/282 (15%)

Query: 4   MIVLKFGGSSVKNDFHEAVSLTKSIFEEKE----VAVVVSALKGITDMLIKYAKTFDSKY 59
           ++V K+GG+SV  D      + + I   +E    +AVVVSA+   TD LI  AK  + + 
Sbjct: 3   LVVQKYGGTSV-GDLERIHKVAQRIAHYREKGHRLAVVVSAMGHTTDELIALAKRVNPR- 60

Query: 60  AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIG-ELLSAVIFAEV 118
                                          PP    D LT     +   LLS  ++A  
Sbjct: 61  -------------------------------PPFRELDLLTTTGEQVSVALLSMQLWAMG 89

Query: 119 VEGQVIYPWEL-FSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGM-DGYR 176
           +  +     ++  +  G++GD  I     + N   I E ++ G + ++ GF+G   +G  
Sbjct: 90  IPAKGFVQHQIGITTDGRYGDARI----LEVNPARIREALEQGFVAVIAGFMGTTPEGEI 145

Query: 177 VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAK 236
            TLGRGGSD +AVA+   L ++   I ++ EG++T DP L+P AR +  + Y++ L  A 
Sbjct: 146 TTLGRGGSDTTAVAIAAALGAKECEIYTDTEGVYTTDPHLIPEARKLSVIGYDQMLEMAA 205

Query: 237 HGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRM 278
            G + +  +A   AK   +++    + ++  GT++      M
Sbjct: 206 LGARVLHPRAVYYAKRYGVVLHVRSSFSYNPGTLVKEVAMEM 247


>gb|AAB49995.1| (U90239) aspartokinase [Mycobacterium tuberculosis]
           Length = 428
           
 Score = 85.0 bits (207), Expect = 1e-15
 Identities = 91/326 (27%), Positives = 146/326 (43%), Gaps = 66/326 (20%)

Query: 4   MIVLKFGGSSVKNDFH-----EAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSK 58
           ++V K+GGSSV +        E +  TK   +  +V VVVSA+   TD L+  A+     
Sbjct: 3   LVVQKYGGSSVADAERIRRVAERIVATKK--QGNDVVVVVSAMGDTTDDLLDLAQQ---- 56

Query: 59  YAIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEV 118
                            V P   +P  +EL            D +L+ GE +S  + A  
Sbjct: 57  -----------------VCP---APPPREL------------DMLLTAGERISNALVAMA 84

Query: 119 VEGQVIYPWELF-SAYGKFGDGFIDLKKSKKNAKII-------YEVIDSGKIPIVPGFVG 170
           +E    +      S  G    G      +  NAKII          ++ G++ +V GF G
Sbjct: 85  IESLGAHARSFTGSQAGVITTG------THGNAKIIDVTPGRLQTALEEGRVVLVAGFQG 138

Query: 171 GMDGYR--VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSY 228
                +   TLGRGGSD +AVA+   L +++  I ++V+GIF+ADP++V +AR +  +++
Sbjct: 139 VSQDTKDVTTLGRGGSDTTAVAMAAALGADVCEIYTDVDGIFSADPRIVRNARKLDTVTF 198

Query: 229 EEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDGLL 288
           EE L  A  G K +  +  E A+   I +    + + R GTV+      +P+   +D +L
Sbjct: 199 EEMLEMAACGAKVLMLRCVEYARRHNIPVHVRSSYSDRPGTVVVGSIKDVPM---EDPIL 255

Query: 289 LINVEEELEYRVIDEGPFWKLYDVPG 314
                +  E +V   G    L D+PG
Sbjct: 256 TGVAHDRSEAKVTIVG----LPDIPG 277


>sp|P97048|AK_MYCTU ASPARTOKINASE (ASPARTATE KINASE) [CONTAINS: ASPARTOKINASE ALPHA
           SUBUNIT (ASK-ALPHA); ASPARTOKINASE BETA SUBUNIT
           (ASK-BETA)] >gi|7434559|pir||F70794 probable ask protein
           - Mycobacterium tuberculosis (strain H37RV)
           >gi|2960133|emb|CAA18031.1| (AL022121) ask
           [Mycobacterium tuberculosis]
           Length = 421
           
 Score = 85.0 bits (207), Expect = 1e-15
 Identities = 91/326 (27%), Positives = 146/326 (43%), Gaps = 66/326 (20%)

Query: 4   MIVLKFGGSSVKNDFH-----EAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSK 58
           ++V K+GGSSV +        E +  TK   +  +V VVVSA+   TD L+  A+     
Sbjct: 3   LVVQKYGGSSVADAERIRRVAERIVATKK--QGNDVVVVVSAMGDTTDDLLDLAQQ---- 56

Query: 59  YAIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEV 118
                            V P   +P  +EL            D +L+ GE +S  + A  
Sbjct: 57  -----------------VCP---APPPREL------------DMLLTAGERISNALVAMA 84

Query: 119 VEGQVIYPWELF-SAYGKFGDGFIDLKKSKKNAKII-------YEVIDSGKIPIVPGFVG 170
           +E    +      S  G    G      +  NAKII          ++ G++ +V GF G
Sbjct: 85  IESLGAHARSFTGSQAGVITTG------THGNAKIIDVTPGRLQTALEEGRVVLVAGFQG 138

Query: 171 GMDGYR--VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSY 228
                +   TLGRGGSD +AVA+   L +++  I ++V+GIF+ADP++V +AR +  +++
Sbjct: 139 VSQDTKDVTTLGRGGSDTTAVAMAAALGADVCEIYTDVDGIFSADPRIVRNARKLDTVTF 198

Query: 229 EEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNRTSRMPLMTYKDGLL 288
           EE L  A  G K +  +  E A+   I +    + + R GTV+      +P+   +D +L
Sbjct: 199 EEMLEMAACGAKVLMLRCVEYARRHNIPVHVRSSYSDRPGTVVVGSIKDVPM---EDPIL 255

Query: 289 LINVEEELEYRVIDEGPFWKLYDVPG 314
                +  E +V   G    L D+PG
Sbjct: 256 TGVAHDRSEAKVTIVG----LPDIPG 277


>gb|AAK41163.1| Aspartokinase (akH) [Sulfolobus solfataricus]
           Length = 446
           
 Score = 84.7 bits (206), Expect = 2e-15
 Identities = 82/271 (30%), Positives = 135/271 (49%), Gaps = 45/271 (16%)

Query: 5   IVLKFGGSSVKNDFHEAVSLTKSI--FEEK--EVAVVVSALKGITDMLIKYAKTFDS--- 57
           +++K GGS ++ D  +   + K I  F +K  ++ VV SA+K +T+ LI      D+   
Sbjct: 3   LIVKIGGS-IQKDEKDYELIVKKIQDFSKKSDKIIVVTSAIKNVTNELISATSNTDNSPN 61

Query: 58  ----------KYAIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPK--DALT----D 101
                     K   K+AD   K    +  D + LS    ELF      +  D +T    D
Sbjct: 62  IVTEIYERHIKLLSKLADG--KEFENSFKDISRLS---DELFRVAWSIRVLDEVTPRVRD 116

Query: 102 YILSIGELLSAVIFAEVV-------EGQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIY 154
           YILS GE ++ ++ + ++       EG +  P+     YG+  +   DL K++     I 
Sbjct: 117 YILSFGERMATLLLSAILRSNGIEAEGIITPPFLTDENYGE-ANVIEDLSKNE-----IA 170

Query: 155 EVIDSGK--IPIVPGFVGGM-DGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFT 211
            ++++ K  + ++PGF+G   +G   TLGRGGSDY+A  LG ++    V +++ V GI T
Sbjct: 171 NILENAKANVIVLPGFIGRTREGRYTTLGRGGSDYTATLLGKLVGVREVRLVTEVPGIMT 230

Query: 212 ADPKLVPSARLIPYLSYEEALIAAKHGMKAI 242
            DPK   +A+ I  LS EEA+  ++ G K +
Sbjct: 231 GDPKKFENAKTISRLSLEEAIELSQLGAKRL 261


>dbj|BAB06815.1| (AP001517) aspartokinase II alpha and beta subunits [Bacillus
           halodurans]
           Length = 412
           
 Score = 84.7 bits (206), Expect = 2e-15
 Identities = 77/279 (27%), Positives = 126/279 (44%), Gaps = 52/279 (18%)

Query: 4   MIVLKFGGSSV---KNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
           +IV K+GG+SV   +   H A  +  +    K+V VVVSA+   TD L+  A        
Sbjct: 3   IIVQKYGGTSVGSVQRIEHVANRIIATAASGKKVVVVVSAMGKTTDELVGLAS------- 55

Query: 61  IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVV- 119
            +I D                             P+    D +L+ GE ++  + A  + 
Sbjct: 56  -EITDE----------------------------PRKREMDMLLATGEQVTIALLAMALH 86

Query: 120 ----EGQVIYPWE--LFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVG-GM 172
               E   +  W+  + +         +++++++ +     E++D   + IV GF G   
Sbjct: 87  KRGQEATSLTGWQAGMITESHHGNARILEVERARMD-----ELLDKVHVVIVAGFQGIDQ 141

Query: 173 DGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEAL 232
            G  +TLGRGGSD SAVA+   L +E   I ++V G+FT DP++V  AR +  +SY+E L
Sbjct: 142 QGEIMTLGRGGSDTSAVAIAAALKAERCEIYTDVTGVFTTDPRVVKQARKLQTISYDEML 201

Query: 233 IAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVI 271
             A  G   +  +A E AK  +I +L   +     GT+I
Sbjct: 202 EMANLGASVLHPRAVEFAKNYEIPLLVASSMVDEPGTMI 240


>pir||G72245 aspartokinase II - Thermotoga maritima (strain MSB8)
           >gi|4982084|gb|AAD36585.1|AE001799_17 (AE001799)
           aspartokinase II [Thermotoga maritima]
           Length = 401
           
 Score = 84.3 bits (205), Expect = 2e-15
 Identities = 80/277 (28%), Positives = 124/277 (43%), Gaps = 43/277 (15%)

Query: 4   MIVLKFGGSSVKNDF---HEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
           ++V K+GGSSV       + A  + K + E  +V VVVSA+   TD LIK AK    +  
Sbjct: 3   VVVQKYGGSSVATPERIKNVAQRIKKKVDEGYKVVVVVSAMGKTTDNLIKLAKEISPR-- 60

Query: 61  IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
                                 P  +EL            D +L+ GE +SA + +  ++
Sbjct: 61  ----------------------PDSREL------------DMLLATGEQVSAALLSMALK 86

Query: 121 GQVIYPWEL--FSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGMD-GYRV 177
              +    L  F    K        +    +  +I E +    + +V GF G  + G   
Sbjct: 87  DLGVKAKSLNAFQVKIKTTPHHTSARIVDIDDSVIRENLKDYDVLVVTGFQGVNEHGDLT 146

Query: 178 TLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAKH 237
           TLGRGGSD SAVAL   L      I S+V+GI+T DP++ P A+ + Y++Y+EAL     
Sbjct: 147 TLGRGGSDTSAVALAAKLRVPC-EIYSDVDGIYTCDPRVHPRAKKLAYITYDEALELTAL 205

Query: 238 GMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISNR 274
           G K +  ++ E+AK+  I +    +     GT++  R
Sbjct: 206 GAKVLHSRSVEIAKKYGIPIYCASSFTEEEGTMVVER 242


>gb|AAF03452.1|AC010797_28 (AC010797) putative aspartate kinase [Arabidopsis thaliana]
           >gi|6513929|gb|AAF14833.1|AC011664_15 (AC011664)
           putative aspartate kinase [Arabidopsis thaliana]
           Length = 559
           
 Score = 83.9 bits (204), Expect = 3e-15
 Identities = 77/298 (25%), Positives = 142/298 (46%), Gaps = 36/298 (12%)

Query: 6   VLKFGGSSVKNDFHEAVSLTKSI--FEEKEVAVVVSALKGITDMLIKYAK---------- 53
           V+KFGGSSV +     + + K I  F +++  VV+SA+   T+ L+   +          
Sbjct: 86  VMKFGGSSVASA-ERMIQVAKLILSFPDEKPVVVLSAMAKTTNKLLMAGEKAVCCGVTNV 144

Query: 54  -TFDSKYAIKIADSYVKFARTNGVDPNILSPHIQ---ELFNPPSLPKDALT---DYILSI 106
            T +    IK  + +++ A   GV+  +++ H++   +L    ++ K+      DY++S 
Sbjct: 145 DTIEELSYIK--ELHIRTAHELGVETAVIAEHLEGLEQLLKGVAMMKELTLRSRDYLVSF 202

Query: 107 GELLSAVIFAEVVE--GQVIYPWELFSAYGKFGDGF-----IDLKKSKKNAKIIYEVIDS 159
           GE +S  +FA  +   G     ++ F       D F     ++      + K++ +    
Sbjct: 203 GECMSTRLFAAYLNKIGHKARQYDAFEIGIITTDDFTNADILEATYPAVSKKLLGDWSKE 262

Query: 160 GKIPIVPGFVGGMDGYR----VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPK 215
             +P+V GF+G   G+R     TLGRGGSD +A  +G  L    + +  +V+G+ T DP 
Sbjct: 263 NALPVVTGFLG--KGWRSCAVTTLGRGGSDLTATTIGKALGLREIQVWKDVDGVLTCDPN 320

Query: 216 LVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKI-LMLFGRTNNWRMGTVIS 272
           +   A+ +P+L+++EA   A  G + +   +   A+E  I + +    N    GTVI+
Sbjct: 321 IYCGAQPVPHLTFDEAAELAYFGAQVLHPLSMRPAREGNIPVRVKNSYNPTAPGTVIT 378


>emb|CAC06395.1| (Y16255) aspartate kinase [Arabidopsis thaliana]
           Length = 544
           
 Score = 83.5 bits (203), Expect = 4e-15
 Identities = 75/297 (25%), Positives = 139/297 (46%), Gaps = 34/297 (11%)

Query: 6   VLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDML----------IKYAK 53
           V+KFGGSSV +     E  +L  S  +E+ V V+ +  K I  +L          +   +
Sbjct: 85  VMKFGGSSVGSAERMKEVANLIFSFPDERPVIVLSAMGKTINKLLKAGEKAVTCGVTNVE 144

Query: 54  TFDSKYAIKIADSYVKFARTNGVDPNILSPHIQ---ELFNPPSLPKDALT---DYILSIG 107
           + +    IK  + +++ A   GV+  ++  H++   +L    S+ K+      DY++S G
Sbjct: 145 SIEELSFIK--ELHLRTAHELGVETTVIEKHLEGLHQLLKGISMMKELTLRTRDYLVSFG 202

Query: 108 ELLSAVIFAEVVE--GQVIYPWELFSAYGKFGDGF-----IDLKKSKKNAKIIYEVIDSG 160
           E +S  +F+  +   G     ++ F       D F     ++      +  ++ +     
Sbjct: 203 ECMSTRLFSAYLNKIGHKARQYDAFEIGFITTDDFTNADILEATYPAVSKTLVGDWSKEN 262

Query: 161 KIPIVPGFVGGMDGYR----VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKL 216
            +P+V G++G   G+R     TLGRGGSD +A  +G  L    + +  +V+G+ T DP +
Sbjct: 263 AVPVVTGYLG--KGWRSCAITTLGRGGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNI 320

Query: 217 VPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKI-LMLFGRTNNWRMGTVIS 272
            P A+ +PYL+++EA   A  G + +   +   A++  I + +    N    GTVI+
Sbjct: 321 YPGAQSVPYLTFDEAAELAYFGAQVLHPLSMRPARDGDIPVRVKNSYNPTAPGTVIT 377


>gb|AAB63104.1| (U62020) lysine-sensitive aspartate kinase [Arabidopsis thaliana]
           Length = 544
           
 Score = 82.7 bits (201), Expect = 6e-15
 Identities = 75/295 (25%), Positives = 136/295 (45%), Gaps = 30/295 (10%)

Query: 6   VLKFGGSSVKND--FHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDS------ 57
           V+KFGGSSV +     E  +L  S  +E+ V V+ +  K I  +L    K          
Sbjct: 85  VMKFGGSSVGSAERMKEVANLIFSFPDERPVIVLSAMGKTINKLLKAGEKAVTCGVTNVG 144

Query: 58  --KYAIKIADSYVKFARTNGVDPNILSPHIQ---ELFNPPSLPKDALT---DYILSIGEL 109
             +    I + +++ A   GV+  ++  H++   +L    S+ K+      DY++S GE 
Sbjct: 145 SIEELSFIKELHLRTAHELGVETTVIEKHLEGLHQLLKGISMMKELTLRTRDYLVSFGEC 204

Query: 110 LSAVIFAEVVE--GQVIYPWELFSAYGKFGDGF-----IDLKKSKKNAKIIYEVIDSGKI 162
           +S  +F+  +   G     ++ F       D F     ++      +  ++ +      +
Sbjct: 205 MSTRLFSAYLNKIGHKARQYDAFEIGFITTDDFTNADILEATYPAVSKTLVGDWSKENAV 264

Query: 163 PIVPGFVGGMDGYR----VTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVP 218
           P+V G++G   G+R     TLGRGGSD +A  +G  L    + +  +V+G+ T DP + P
Sbjct: 265 PVVTGYLG--KGWRSCAITTLGRGGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIYP 322

Query: 219 SARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKI-LMLFGRTNNWRMGTVIS 272
            A+ +PYL+++EA   A  G + +   +   A++  I + +    N    GTVI+
Sbjct: 323 GAQSVPYLTFDEAAELAYFGAQVLHPLSMRPARDGDIPVRVKNSYNPTAPGTVIT 377


>pir||D81681 aspartokinase III TC0641 [imported] - Chlamydia muridarum  (strain
           Nigg) >gi|7190680|gb|AAF39470.1| (AE002332)
           aspartokinase III [Chlamydia muridarum]
           Length = 437
           
 Score = 82.3 bits (200), Expect = 8e-15
 Identities = 71/247 (28%), Positives = 119/247 (47%), Gaps = 11/247 (4%)

Query: 5   IVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKT---FDSKYAI 61
           +V KFGG+SV         + + I +EK   VVVSA+ G+TD+L ++ +      S++  
Sbjct: 9   LVCKFGGTSVGTS-SSIQRVCEIIRKEKPSFVVVSAVAGVTDLLEEFCRAPVGQKSQFTA 67

Query: 62  KIADSYVKFARTNGVDPNILSPHIQEL--FNPPSLPKDALTDYILSIGELLSAVIFAEVV 119
            I + +   A+  G+D  I  P +  L  F      +      IL+IGE LSA +     
Sbjct: 68  MIREKHESIAKELGIDVAI-EPFLGPLKQFEGAGHLQQEDQAKILAIGEDLSASLICSYC 126

Query: 120 EGQVIYPWELFSAYGKFGDG-FIDLKKSKKNAKIIYE--VIDSGKIPIVPGFVGGM-DGY 175
               +   +L +      D  F+  +      + ++   V+    I ++ GF+G    G 
Sbjct: 127 RANSLQLEQLEARQVILTDSQFLRAEPDLALMQTMWGELVLKENTIYLMQGFLGATASGA 186

Query: 176 RVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAA 235
              LGRGGSD+SA  +G +  +  + I ++V G+ TADPK++   +LI +L++EE    A
Sbjct: 187 TTVLGRGGSDFSASLVGELCEARELRIYTDVRGVHTADPKILKDTQLIDFLTFEEMQELA 246

Query: 236 KHGMKAI 242
             G K +
Sbjct: 247 SSGSKVL 253


>emb|CAC11508.1| (AL445064) aspartate kinase related protein [Thermoplasma
           acidophilum]
           Length = 272
           
 Score = 81.1 bits (197), Expect = 2e-14
 Identities = 82/283 (28%), Positives = 125/283 (43%), Gaps = 23/283 (8%)

Query: 1   MRKMIVLKFGGSSVKNDFHEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
           M +  V+K GGS +K D      +   I   +   +VVSA  GITD L ++ + +D    
Sbjct: 1   MTEKCVIKIGGSVLK-DGSSLPRVMDIISHFRSPILVVSAFGGITDALYRFYE-YDESRM 58

Query: 61  IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDY--ILSIGELLSAVIFAEV 118
            K+ D  +           IL  +  E     S+   ++ D    +S GE +SA   A  
Sbjct: 59  DKLRDLLLMHL-------GILWKYNIEAHPEISIQDSSILDQDAYVSYGEKMSAFTLARF 111

Query: 119 VEGQVIYPWELFSAYGKF------GDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVGGM 172
           + G  I    +++            +  +DL+ S+   + I  V  SGK+P+V GF G +
Sbjct: 112 LTGNGIPAAPIYTDEAGLIVEEISKERTVDLEGSRAFFENIARVETSGKVPVVTGFFG-I 170

Query: 173 DGYRVT--LGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEE 230
           D Y  T  LGR  SDYSAVA+  IL    V ++ +V GI+     L     ++  + YE 
Sbjct: 171 DRYGKTRILGRNSSDYSAVAVAAILGIREVILIKDVPGIYM---NLEDRTSIVNRIDYET 227

Query: 231 ALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRMGTVISN 273
           AL     G K +   A  LA +  + +L     N   GTVI +
Sbjct: 228 ALRIVDRGSKVVHRAALRLAMKMGMNLLITSPENLESGTVIGD 270


>pir||F75405 aspartate kinase - Deinococcus radiodurans (strain R1)
           >gi|6459119|gb|AAF10936.1|AE001982_10 (AE001982)
           aspartate kinase [Deinococcus radiodurans]
           Length = 473
           
 Score = 80.4 bits (195), Expect = 3e-14
 Identities = 82/313 (26%), Positives = 143/313 (45%), Gaps = 43/313 (13%)

Query: 3   KMIVLKFGGSSVKNDF---HEAVSLTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKY 59
           +++V+KFGG+++++     H A    +S+ E  +V VVVSA+ G+T+ L+  A    S  
Sbjct: 9   RLLVMKFGGTNMQSAHAIRHSASLAGRSVREGVKVVVVVSAMAGVTNGLLHLADAAQSGD 68

Query: 60  AIKIADSYVKF-------ARTNGVDPNILSPHIQELFNPPSLPKDAL------------- 99
             +  D            A+  G  P+  S  ++EL       + A+             
Sbjct: 69  IARANDEIAALRTRHFTAAQELGAAPD--SETVRELRELHETLRQAVYGVYLLRELTPRS 126

Query: 100 TDYILSIGELLSAVIFAEVVEGQVIYPWELFSAYGKFGDGFIDLKKSKKNAKII---YE- 155
            D I++ GE LSA + +  +E   +    L       G+  I    +  NA+ +   YE 
Sbjct: 127 RDLIVAFGERLSAPLMSLALEQSGLRARHLTG-----GEAGILTDTNFGNARPLPGTYER 181

Query: 156 -------VIDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVE 207
                   + +G  P++ GF+G  + G   TLGRGG+D+SA  +G  L ++ V    +V+
Sbjct: 182 VGDRLSGFLSAGVTPVIAGFMGETEQGAITTLGRGGTDFSATIVGKALGADEVWAWKDVD 241

Query: 208 GIFTADPKLVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKI-LMLFGRTNNWR 266
           G+ +ADP++V  A  I  LSY E +  A  G K +   A    ++  I L +    +   
Sbjct: 242 GVMSADPRVVGDASNIGVLSYGEVMELAYFGAKVLHPLAVTPLQDSGIPLRVKSAADPDF 301

Query: 267 MGTVISNRTSRMP 279
            GT++ ++   +P
Sbjct: 302 AGTLVRSQAEEIP 314


>emb|CAB57346.1| (Y15939) aspartokinase [Dichelobacter nodosus]
           Length = 206
           
 Score = 79.6 bits (193), Expect = 5e-14
 Identities = 47/137 (34%), Positives = 79/137 (57%), Gaps = 2/137 (1%)

Query: 153 IYEVIDSGKIPIVPGFVGGMD-GYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFT 211
           IY  + +GK+ IV GF G  + G   TLGRGGSD +AVAL  +L ++   I ++V+G++T
Sbjct: 9   IYRALSAGKVVIVAGFQGVDEAGDITTLGRGGSDTTAVALAAVLKADECQIYTDVDGVYT 68

Query: 212 ADPKLVPSARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKI-LMLFGRTNNWRMGTV 270
            DP++ P AR +  +S+ E L  A  G K +Q ++ E A +  + + +    ++   GT+
Sbjct: 69  TDPRIEPRARKLEQISFVEMLEMASLGSKVLQIRSVEFAGKYHVPVRVLSSFSDDETGTL 128

Query: 271 ISNRTSRMPLMTYKDGL 287
           IS+    +   T+  G+
Sbjct: 129 ISSVEGAIIEATHVTGI 145


>pir||C83531 aspartate kinase alpha and beta chain PA0904 [imported] -
           Pseudomonas aeruginosa (strain PAO1)
           >gi|9946806|gb|AAG04293.1|AE004525_1 (AE004525)
           aspartate kinase alpha and beta chain [Pseudomonas
           aeruginosa]
           Length = 412
           
 Score = 76.9 bits (186), Expect = 4e-13
 Identities = 84/310 (27%), Positives = 137/310 (44%), Gaps = 45/310 (14%)

Query: 4   MIVLKFGGSSVKN-DFHEAVSLTKSIFEEK--EVAVVVSALKGITDMLIKYAKTFDSKYA 60
           +IV KFGG+SV   +  E V+     F E   +V VVVSA+ G T+ LI  A     +  
Sbjct: 3   LIVQKFGGTSVGTVERIEQVAEKVKKFREAGDDVVVVVSAMSGETNRLIGLANQIMEQPV 62

Query: 61  IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
            +  D  V                            + +T  +LS+  +   V       
Sbjct: 63  PRELDVMVSTG-------------------------EQVTIALLSMALIKRGVPAVSYTG 97

Query: 121 GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVG-GMDGYRVTL 179
            QV    +  SA+ K     ID    + + K       +G++ +V GF G   +G   TL
Sbjct: 98  NQVRILTD--SAHTKARILHIDDTHIRADLK-------AGRVVVVAGFQGVDGNGNITTL 148

Query: 180 GRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAKHGM 239
           GRGGSD + VAL   L ++   I ++V+G++T DP++VP AR +  +++EE L  A  G 
Sbjct: 149 GRGGSDTTGVALAAALKADECQIYTDVDGVYTTDPRVVPQARRLDKITFEEMLEMASLGS 208

Query: 240 KAIQWKAAELAKEKKILMLFGRTNNWRMGTVIS----NRTSRMPLMTYKDGLLLINVEEE 295
           K +Q +A E A +  + +    +     GT+I+      +   P+++   G+     E +
Sbjct: 209 KVLQIRAVEFAGKYNVPLRVLHSFQEGPGTLITIDDEEESMEQPIIS---GIAFNRDEAK 265

Query: 296 LEYRVIDEGP 305
           L  R + + P
Sbjct: 266 LTIRGVPDTP 275


>pir||T39822 aspartate kinase - fission yeast (Schizosaccharomyces pombe)
           >gi|3080523|emb|CAA18652.1| (AL022599) aspartate kinase
           [Schizosaccharomyces pombe]
           Length = 519
           
 Score = 76.5 bits (185), Expect = 5e-13
 Identities = 77/278 (27%), Positives = 129/278 (45%), Gaps = 47/278 (16%)

Query: 5   IVLKFGGSSV-KNDFHEAVSLTKSIFEEKEVAVVVSA------LKGITDMLIKYAKTFDS 57
           +V KFGG+SV K     AV + K     K VA+V SA       +G T  LI+ A     
Sbjct: 16  VVQKFGGTSVGKFPIKIAVDVAKEYLSTKRVALVCSARSTDTKAEGTTTRLIR-ATEAAL 74

Query: 58  KYAIKIADSYVKFARTN------------GVDPNILSP------HIQELFNPPSLPKDA- 98
           + A+      V+   T+            G+   ++         +++  N   +  +  
Sbjct: 75  RPAVGSVHDLVRIIETDHVQAARDFIQDVGIQDELIDAFHADCVELEQYLNAIRVLSEVS 134

Query: 99  --LTDYILSIGELLSAVIFAEVVEGQVIYPWELFSAYGKFGDGFIDLKKSKKN------- 149
               D ++ +GE LS    A V++ Q I    +  ++       ID ++  +N       
Sbjct: 135 PRTRDLVIGMGERLSCRFMAAVLKDQGIDSEFIDMSH------IIDEQREWRNLDASFYA 188

Query: 150 ---AKIIYEVIDSG-KIPIVPGFVGGMDGYRVT-LGRGGSDYSAVALGVILNSELVAIMS 204
              +++  +V   G K+P+V GF G + G  ++ +GRG +D+ A  L V LN++ + I  
Sbjct: 189 YLASQLASKVTAVGNKVPVVTGFFGMVPGGLLSQIGRGYTDFCAALLAVGLNADELQIWK 248

Query: 205 NVEGIFTADPKLVPSARLIPYLSYEEALIAAKHGMKAI 242
            V+GIFTADP+ VP+ARL+P ++ EEA     +G + I
Sbjct: 249 EVDGIFTADPRKVPTARLLPLITPEEAAELTYYGSEVI 286


>pir||S76764 hypothetical protein - Synechocystis sp. (strain PCC 6803)
           >gi|1653765|dbj|BAA18676.1| (D90916) aspartate kinase
           [Synechocystis sp.]
           Length = 600
           
 Score = 74.9 bits (181), Expect = 1e-12
 Identities = 71/254 (27%), Positives = 119/254 (45%), Gaps = 40/254 (15%)

Query: 4   MIVLKFGGSSVKN-DFHEAVS--LTKSIFEEKEVAVVVSALKGITDMLIKYAKTFDSKYA 60
           +IV KFGG+SV   +  +AV+  + +++     + VVVSA+   TD+L+  A+       
Sbjct: 3   LIVQKFGGTSVGTVERIQAVAQRIKRTVQGGNSLVVVVSAMGKSTDVLVDLAQQISPNPC 62

Query: 61  IKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPKDALTDYILSIGELLSAVIFAEVVE 120
            +  D  +       V   +LS  +QE+  P           I   G  +  V  AE   
Sbjct: 63  RREMDMLLSTGEQ--VSIALLSLALQEIDQPA----------ISLTGAQVGIVTEAEHSR 110

Query: 121 GQVIYPWELFSAYGKFGDGFIDLKKSKKNAKIIYEVIDSGKIPIVPGFVG--GMDGYRVT 178
            +++                 +++  +     +   +  GK+ +V GF G   ++   +T
Sbjct: 111 ARIL-----------------EIRPDR-----LEHHLREGKVVVVAGFQGISSVEHLEIT 148

Query: 179 -LGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPSARLIPYLSYEEALIAAKH 237
            LGRGGSD SAVAL   L ++   I ++V GI T DP+LVP A+L+  ++ +E L  A  
Sbjct: 149 TLGRGGSDTSAVALAAALKADFCEIYTDVPGILTTDPRLVPEAQLMAEITCDEMLELASL 208

Query: 238 GMKAIQWKAAELAK 251
           G K +  +A E+A+
Sbjct: 209 GAKVLHPRAVEIAR 222


>dbj|BAA95630.1| (AB042521) aspartate kinase [Oryza sativa]
           Length = 354
           
 Score = 71.0 bits (171), Expect = 2e-11
 Identities = 41/116 (35%), Positives = 65/116 (55%), Gaps = 3/116 (2%)

Query: 162 IPIVPGFVGG--MDGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFTADPKLVPS 219
           IPIV GF+G     G   TLGRGGSD +A  +G  L    + +  +V+G+ T DP + P+
Sbjct: 64  IPIVTGFLGKGWKSGAVTTLGRGGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIYPN 123

Query: 220 ARLIPYLSYEEALIAAKHGMKAIQWKAAELAKEKKILMLFGRTNNWRM-GTVISNR 274
           A  +PYL++EEA   A  G + +  ++   A+E  I +    + N +  GT+I+ +
Sbjct: 124 ATTVPYLTFEEAAELAYFGAQVLHPQSMRPAREGDIPVRVKNSYNPKAPGTLITKQ 179


>pir||T04752 aspartate kinase (EC 2.7.2.4) / homoserine dehydrogenase (EC
           1.1.1.3) T16H5.70 - Arabidopsis thaliana
           >gi|3250680|emb|CAA19688.1| (AL024486) aspartate
           kinase-homoserine dehydrogenase-like protein
           [Arabidopsis thaliana] >gi|7268767|emb|CAB78973.1|
           (AL161551) aspartate kinase-homoserine
           dehydrogenase-like protein [Arabidopsis thaliana]
           Length = 916
           
 Score = 69.5 bits (167), Expect = 6e-11
 Identities = 70/260 (26%), Positives = 117/260 (44%), Gaps = 43/260 (16%)

Query: 6   VLKFGGSSVKNDFHEAVSLTKSIFEE--KEVAVVVSALKGITDM---LIKYAKTFDSKY- 59
           V KFGG+ V N      ++ + I  +  +   VVVSA+  +TDM   LI+ A++ D  Y 
Sbjct: 91  VHKFGGTCVGNS-QRIRNVAEVIINDNSERKLVVVSAMSKVTDMMYDLIRKAQSRDDSYL 149

Query: 60  -AIKIADSYVKFARTNGVDPNILSPHIQELFNPPSLPK-------------DALTDYILS 105
            A++      +    + +D + L+  +  L N  S  K             ++ +D++  
Sbjct: 150 SALEAVLEKHRLTARDLLDGDDLASFLSHLHNDISNLKAMLRAIYIAGHASESFSDFVAG 209

Query: 106 IGELLSAVIFAEVVEGQ-------------VIYPWELFSAYGKFGDGFIDLKKSKKNAKI 152
            GEL SA + + VV                ++ P         FG+    L K       
Sbjct: 210 HGELWSAQMLSYVVRKTGLECKWMDTRDVLIVNPTSSNQVDPDFGESEKRLDK------- 262

Query: 153 IYEVIDSGKIPIVPGFVGGM-DGYRVTLGRGGSDYSAVALGVILNSELVAIMSNVEGIFT 211
            +  ++  KI I  GF+         TL R GSD+SA  +G +L +  V I ++V+G+++
Sbjct: 263 -WFSLNPSKIIIATGFIASTPQNIPTTLKRDGSDFSAAIMGALLRARQVTIWTDVDGVYS 321

Query: 212 ADPKLVPSARLIPYLSYEEA 231
           ADP+ V  A ++  LSY+EA
Sbjct: 322 ADPRKVNEAVILQTLSYQEA 341


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.320    0.139    0.400 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 134894577
Number of Sequences: 2977
Number of extensions: 5652565
Number of successful extensions: 13051
Number of sequences better than 1.0e-10: 65
Number of HSP's better than  0.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 41
Number of HSP's that attempted gapping in prelim test: 12937
Number of HSP's gapped (non-prelim): 92
length of query: 368
length of database: 189,106,746
effective HSP length: 56
effective length of query: 312
effective length of database: 155,591,474
effective search space: 48544539888
effective search space used: 48544539888
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 166 (69.1 bits)