BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1678 (asd) DE:aspartate-semialdehyde dehydrogenase (asd)
(335 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||F75080 aspartate-semialdehyde dehydrogenase (asd) PAB1678 -... 669 0.0
pir||E71103 probable aspartate-semialdehyde dehydrogenase - Pyro... 577 e-164
gi|11499101 aspartate-semialdehyde dehydrogenase (asd) [Archaeog... 333 2e-90
sp|Q57658|DHAS_METJA ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA D... 320 2e-86
sp|O26890|DHAS_METTH ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA D... 307 1e-82
pir||H72715 probable aspartate-semialdehyde dehydrogenase APE114... 265 7e-70
gb|AAG19747.1| (AE005060) aspartate-semialdehyde dehydrogenase; ... 259 4e-68
gb|AAK41162.1| Aspartate-semialdehyde dehydrogenase (ASA dehydro... 230 2e-59
sp|P41394|DHAS_LEPIN ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA D... 226 4e-58
pir||T42373 probable aspartate-semialdehyde dehydrogenase (EC 1.... 206 2e-52
pir||T41167 hypothetical protein SPCC1827.06c - fission yeast (... 206 2e-52
emb|CAC11507.1| (AL445064) aspartate-semialdehyde dehydrogenase ... 199 4e-50
gb|AAK42353.1| Aspartate-semialdehyde dehydrogenase (ASA dehydro... 197 2e-49
gb|AAB03213.1| (U44901) aspartate semialdehyde dehydrogenase [Us... 192 5e-48
gi|6320362 aspartic beta semi-aldehyde dehydrogenase; Hom2p [Sac... 190 2e-47
pir||H71524 probable aspartate dehydrogenase - Chlamydia trachom... 168 7e-41
pir||G72002 aspartate dehydrogenase - Chlamydophila pneumoniae (... 166 3e-40
dbj|BAA99255.1| (AP002548) aspartate dehydrogenase [Chlamydophil... 165 6e-40
gb|AAF73580.1| (AE002332) aspartate-semialdehyde dehydrogenase [... 165 8e-40
sp|O67716|DHAS_AQUAE ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA D... 123 3e-27
pir||D72246 aspartate-semialdehyde dehydrogenase - Thermotoga ma... 116 3e-25
pir||E75326 aspartate-semialdehyde dehydrogenase - Deinococcus r... 115 1e-24
dbj|BAB06120.1| (AP001515) aspartate-semialdehyde dehydrogenase ... 109 6e-23
pir||G82690 aspartate-B-semialdehyde dehydrogenase XF1371 [impor... 106 5e-22
sp|Q04797|DHAS_BACSU ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA D... 106 5e-22
pir||D46665 aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) -... 104 1e-21
sp|O25801|DHAS_HELPY ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA D... 103 3e-21
sp|Q9ZK28|DHAS_HELPJ ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA D... 103 3e-21
pir||S14523 aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) -... 102 4e-21
sp|P23247|DHAS_VIBCH ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA D... 102 4e-21
pir||B82118 probable aspartate-semialdehyde dehydrogenase VC2107... 102 4e-21
emb|CAA66607.1| (X97964) aspartate-semialdehyde dehydrogenase [C... 102 6e-21
sp|O31219|DHAS_LEGPN ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA D... 102 6e-21
sp|Q59291|DHAS_CAMJE ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA D... 102 8e-21
emb|CAA75569.1| (Y15281) aspartate-semialdehyde dehydrogenase [V... 101 1e-20
gb|AAG33078.1|AF207064_1 (AF207064) aspartate-semialdehyde dehyd... 98 2e-19
sp|Q56734|DHAS_SHEVI ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA D... 97 3e-19
gb|AAC43359.1| (U25070) aspartate-semialdehyde dehydrogenase [Vi... 96 6e-19
gb|AAC43361.1| (U25072) aspartate-semialdehyde dehydrogenase [Vi... 96 7e-19
gb|AAC43355.1| (U25065) aspartate-semialdehyde dehydrogenase [Vi... 95 1e-18
gb|AAC43356.1| (U25066) aspartate-semialdehyde dehydrogenase [Vi... 95 1e-18
gb|AAC43358.1| (U25069) aspartate-semialdehyde dehydrogenase [Vi... 95 1e-18
gb|AAC43363.1| (U25074) aspartate-semialdehyde dehydrogenase [Vi... 95 1e-18
gb|AAC43365.1| (U25076) aspartate-semialdehyde dehydrogenase [Vi... 95 1e-18
gb|AAC43371.1| (U25082) aspartate-semialdehyde dehydrogenase [Vi... 95 1e-18
sp|Q56732|DHAS_SHESP ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA D... 94 2e-18
gb|AAC43368.1| (U25079) aspartate-semialdehyde dehydrogenase [Vi... 94 3e-18
sp|Q60080|DHAS_VIBMI ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA D... 93 4e-18
gb|AAC43367.1| (U25078) aspartate-semialdehyde dehydrogenase [Vi... 93 5e-18
pir||T35382 probable aspartate-semialdehyde dehydrogenase - Stre... 92 1e-17
emb|CAB71815.1| (AL138662) aspartate semialdehyde dehydrogenase ... 89 6e-17
gb|AAF79239.1|AC006917_24 (AC006917) F10B6.22 [Arabidopsis thali... 89 6e-17
gb|AAD49569.1|AF134837_3 (AF134837) aspartate-semialdehyde dehyd... 85 1e-15
sp|Q9ZDL2|DHAS_RICPR ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA D... 82 1e-14
sp|P41404|DHAS_MYCSM ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA D... 80 5e-14
sp|Q53612|DHAS_STRAK ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA D... 80 5e-14
emb|CAA80276.1| (Z22554) Asd protein [Bacillus subtilis] 78 1e-13
sp|Q55512|DHAS_SYNY3 ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA D... 70 4e-11
>pir||F75080 aspartate-semialdehyde dehydrogenase (asd) PAB1678 - Pyrococcus
abyssi (strain Orsay) >gi|5458459|emb|CAB49947.1|
(AJ248286) aspartate-semialdehyde dehydrogenase (asd)
[Pyrococcus abyssi]
Length = 335
Score = 669 bits (1707), Expect = 0.0
Identities = 335/335 (100%), Positives = 335/335 (100%)
Query: 1 MKRVAVLGATGLVGRTFVKLLGGHPWFKVEKLIASEKSAGKKYGDLVEDSPEEFRDYYVI 60
MKRVAVLGATGLVGRTFVKLLGGHPWFKVEKLIASEKSAGKKYGDLVEDSPEEFRDYYVI
Sbjct: 1 MKRVAVLGATGLVGRTFVKLLGGHPWFKVEKLIASEKSAGKKYGDLVEDSPEEFRDYYVI 60
Query: 61 SLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNKDH 120
SLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNKDH
Sbjct: 61 SLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNKDH 120
Query: 121 LKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRNFGIKKVRVATMQAISGAGFSGLS 180
LKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRNFGIKKVRVATMQAISGAGFSGLS
Sbjct: 121 LKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRNFGIKKVRVATMQAISGAGFSGLS 180
Query: 181 AYAIQDNVIPFISGEEWKIENESKKIMGKLKGDEIEPASFDVIAIATRVPVIHGHTEAVF 240
AYAIQDNVIPFISGEEWKIENESKKIMGKLKGDEIEPASFDVIAIATRVPVIHGHTEAVF
Sbjct: 181 AYAIQDNVIPFISGEEWKIENESKKIMGKLKGDEIEPASFDVIAIATRVPVIHGHTEAVF 240
Query: 241 VELENPDIKSIREAIENFDPLKDLKLPSYEKPIVYTEIPQPRLHRDRGRGLTVTVGRLER 300
VELENPDIKSIREAIENFDPLKDLKLPSYEKPIVYTEIPQPRLHRDRGRGLTVTVGRLER
Sbjct: 241 VELENPDIKSIREAIENFDPLKDLKLPSYEKPIVYTEIPQPRLHRDRGRGLTVTVGRLER 300
Query: 301 TSEGVKYVALGHNLVRGAAGGSVLNAELAYKLKII 335
TSEGVKYVALGHNLVRGAAGGSVLNAELAYKLKII
Sbjct: 301 TSEGVKYVALGHNLVRGAAGGSVLNAELAYKLKII 335
>pir||E71103 probable aspartate-semialdehyde dehydrogenase - Pyrococcus
horikoshii >gi|3257504|dbj|BAA30187.1| (AP000004) 334aa
long hypothetical aspartate-semialdehyde dehydrogenase
[Pyrococcus horikoshii]
Length = 334
Score = 577 bits (1470), Expect = e-164
Identities = 280/333 (84%), Positives = 309/333 (92%)
Query: 3 RVAVLGATGLVGRTFVKLLGGHPWFKVEKLIASEKSAGKKYGDLVEDSPEEFRDYYVISL 62
+VAVLGATG+VGRTFVKLL HPWFKVEKL+ASE+SAGK+YG++VEDSPEEF+DY +I L
Sbjct: 2 KVAVLGATGVVGRTFVKLLENHPWFKVEKLVASERSAGKRYGEIVEDSPEEFKDYTIIGL 61
Query: 63 NEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNKDHLK 122
EFLE+PGVDLVFNALPASIS++VEEKLAQEIPVFTNAR+HRYDEDVPILVPEVN DHLK
Sbjct: 62 KEFLEDPGVDLVFNALPASISKEVEEKLAQEIPVFTNARSHRYDEDVPILVPEVNSDHLK 121
Query: 123 LVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRNFGIKKVRVATMQAISGAGFSGLSAY 182
LVEVQRKRR W+GFIVTNPNCSTAILT+SLAPLR FGIKKVRVATMQAISGAGFSGLSAY
Sbjct: 122 LVEVQRKRRKWRGFIVTNPNCSTAILTVSLAPLRAFGIKKVRVATMQAISGAGFSGLSAY 181
Query: 183 AIQDNVIPFISGEEWKIENESKKIMGKLKGDEIEPASFDVIAIATRVPVIHGHTEAVFVE 242
AI DNVIPFI+GEEWKIENES+KI+GK GD++EPA +V AIATRVPV+HGHTEAVFVE
Sbjct: 182 AIHDNVIPFINGEEWKIENESRKILGKFTGDKVEPAEIEVAAIATRVPVLHGHTEAVFVE 241
Query: 243 LENPDIKSIREAIENFDPLKDLKLPSYEKPIVYTEIPQPRLHRDRGRGLTVTVGRLERTS 302
LE DI+ IREA ENFDPL+ L+LPSYEKPIVYTEIPQPRLHRDRG+GLTVTVGRL+ S
Sbjct: 242 LEKFDIEEIREAFENFDPLRSLELPSYEKPIVYTEIPQPRLHRDRGKGLTVTVGRLQEIS 301
Query: 303 EGVKYVALGHNLVRGAAGGSVLNAELAYKLKII 335
G+KYV LGHNLVRGAAGGS+LNAELAYKL II
Sbjct: 302 GGIKYVVLGHNLVRGAAGGSILNAELAYKLGII 334
>gi|11499101 aspartate-semialdehyde dehydrogenase (asd) [Archaeoglobus fulgidus]
>gi|6225259|sp|O28766|DHAS_ARCFU ASPARTATE-SEMIALDEHYDE
DEHYDROGENASE (ASA DEHYDROGENASE) (ASADH)
>gi|7447643|pir||A69438 aspartate-semialdehyde
dehydrogenase (asd) homolog - Archaeoglobus fulgidus
>gi|2649055|gb|AAB89738.1| (AE000998)
aspartate-semialdehyde dehydrogenase (asd)
[Archaeoglobus fulgidus]
Length = 343
Score = 333 bits (844), Expect = 2e-90
Identities = 180/343 (52%), Positives = 239/343 (69%), Gaps = 15/343 (4%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKLIASEKSAGKKYGDLVE-----DSPEEFRDYY 58
V VLGATG+VG+ F+++L HPWFK+ L ASE+ GKKYG+ V+ + P+ +D
Sbjct: 5 VGVLGATGMVGQKFIQMLAEHPWFKLTSLAASERRVGKKYGEEVDWIVSREVPDIAKDIE 64
Query: 59 VISLNEFLENPGVDLVFNALPASISRDVEEKLAQE-IPVFTNARAHRYDEDVPILVPEVN 117
++ ++ ++ D+VF+ALP+ I+R+VE K A+ V +NA A+R EDVP+++PEVN
Sbjct: 65 MVPMDP--KHVDADIVFSALPSDIAREVEPKFAEAGFVVASNASAYRMAEDVPLVIPEVN 122
Query: 118 KDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRNFGIKKVRVATMQAISGAGFS 177
+HL L+EVQ+K RGW GFIVTNPNC+T +L LSL PL + G++ VRVA+MQA+SGAG+
Sbjct: 123 PEHLGLIEVQKKNRGWDGFIVTNPNCTTIVLVLSLKPLMDLGLRTVRVASMQALSGAGYP 182
Query: 178 GLSAYAIQDNVIPFISGEEWKIENESKKIMGKLKGDEIEPASFDVIAIATRVPVIHGHTE 237
G+ + AI DNVIPFI GEE K+E E K++GK G +IE A V A RVPVI GHTE
Sbjct: 183 GVPSLAITDNVIPFIKGEEDKVEEEPLKLLGKFNGRKIEFADIKVSASCHRVPVIDGHTE 242
Query: 238 AVFVELENPDIKSIREAIENFDPLKDLKLP-SYEKPIVYTE---IPQPRLHRDRGRGLTV 293
AV+VE + S+ EA F+ LK L LP S EK I+ E PQPRL RD G G+++
Sbjct: 243 AVWVEFDRE--VSVEEAKAAFESLKPLDLPTSPEKVIIVREEPDRPQPRLDRDAGNGMSI 300
Query: 294 TVGRLERTSE-GVKYVALGHNLVRGAAGGSVLNAELAYKLKII 335
TVGR+ + E G+KY+ LGHN VRGAAG S+LNAEL K KII
Sbjct: 301 TVGRIRKDGERGLKYIVLGHNTVRGAAGASILNAELMIKEKII 343
>sp|Q57658|DHAS_METJA ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA DEHYDROGENASE) (ASADH)
>gi|2127777|pir||F64325 aspartate-semialdehyde
dehydrogenase (EC 1.2.1.11) - Methanococcus jannaschii
>gi|1590948|gb|AAB98189.1| (U67476)
aspartate-semialdehyde dehydrogenase (asd)
[Methanococcus jannaschii]
Length = 354
Score = 320 bits (811), Expect = 2e-86
Identities = 170/342 (49%), Positives = 237/342 (68%), Gaps = 13/342 (3%)
Query: 3 RVAVLGATGLVGRTFVKLLGGHPWFKVEKLIASEKSAGKKYGDLV-----EDSPEEFRDY 57
+V VLGATG VG+ FV+LL HP F++ L ASE+SAGKKY D D PE +D
Sbjct: 10 KVGVLGATGSVGQRFVQLLADHPMFELTALAASERSAGKKYKDACYWFQDRDIPENIKDM 69
Query: 58 YVISLN-EFLENPGVDLVFNALPASISRDVEEKLAQEIP-VFTNARAHRYDEDVPILVPE 115
VI + + E VD+VF+ALP+ +++ E + A+E +F+NA A+R +EDVP+++PE
Sbjct: 70 VVIPTDPKHEEFEDVDIVFSALPSDLAKKFEPEFAKEGKLIFSNASAYRMEEDVPLVIPE 129
Query: 116 VNKDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGA 174
VN DHL+L+E+QR++RGW G I+TNPNCST ++L P+ + FG++ V +ATMQA+SGA
Sbjct: 130 VNADHLELIEIQREKRGWDGAIITNPNCSTICAVITLKPIMDKFGLEAVFIATMQAVSGA 189
Query: 175 GFSGLSAYAIQDNVIPFISGEEWKIENESKKIMGKLKGDEIEPASFDVIAIATRVPVIHG 234
G++G+ + AI DN+IPFI EE K++ ES K++G LK ++E A+F + A RV VI G
Sbjct: 190 GYNGVPSMAILDNLIPFIKNEEEKMQTESLKLLGTLKDGKVELANFKISASCNRVAVIDG 249
Query: 235 HTEAVFVEL-ENPDIKSIREAIENFDPLKDLKLPSYEKPIVYTE---IPQPRLHRDRGRG 290
HTE++FV+ E + + I+E ++ FDPLKDL LP+Y KPIV E PQPRL R+ G G
Sbjct: 250 HTESIFVKTKEGAEPEEIKEVMDKFDPLKDLNLPTYAKPIVIREEIDRPQPRLDRNEGNG 309
Query: 291 LTVTVGRLERTS-EGVKYVALGHNLVRGAAGGSVLNAELAYK 331
+++ VGR+ + VKY AL HN +RGAAG SVLNAE K
Sbjct: 310 MSIVVGRIRKDPIFDVKYTALEHNTIRGAAGASVLNAEYFVK 351
>sp|O26890|DHAS_METTH ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA DEHYDROGENASE) (ASADH)
>gi|7447644|pir||E69206 aspartate-semialdehyde
dehydrogenase - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2621889|gb|AAB85299.1| (AE000858)
aspartate-semialdehyde dehydrogenase [Methanobacterium
thermoautotrophicum]
Length = 347
Score = 307 bits (778), Expect = 1e-82
Identities = 170/343 (49%), Positives = 235/343 (67%), Gaps = 16/343 (4%)
Query: 1 MKRVAVLGATGLVGRTFVKLLGGHPWFKVEKLIASEKSAGKKYGDLVE-----DSPEEFR 55
M V VLGATG+VG+ F+++L HP F++ L AS +SAGK YG++ + PE R
Sbjct: 1 MVNVGVLGATGMVGQRFIQMLDKHPEFELTTLAASSRSAGKPYGEVANWYLDCEMPESVR 60
Query: 56 DYYVISLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPE 115
D V+ + VD++F+ALPA ++R VE K A++ V +NA A R + DVP+++PE
Sbjct: 61 DMEVVETDPSAVGD-VDILFSALPADVARKVEPKFAEKYIVASNASAMRMEPDVPLVIPE 119
Query: 116 VNKDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGA 174
VN + L L+EVQ++RRGW GFIVTNPNCST LTL+L P+ + + IK+V V+TMQA+SGA
Sbjct: 120 VNPEFLDLIEVQQRRRGWDGFIVTNPNCSTIALTLTLKPIYDAYTIKRVYVSTMQAVSGA 179
Query: 175 GFSGLSAYAIQDNVIPFISGEEWKIENESKKIMGKLKGDEIEPASFDVIAIATRVPVIHG 234
G++G+ + AI DN++PFI GEE KIE E+ ++G+L ++PASF V A RVPV+ G
Sbjct: 180 GYNGVPSMAILDNLVPFIGGEEEKIETETLHLLGELDEGVVKPASFGVSASCHRVPVVDG 239
Query: 235 HTEAVFVELENP-DIKSIREAIENFDPL-KDLKLPSY-EKPIVYTE---IPQPRLHRDRG 288
HTEAVF+EL++ DI +REA++ F L + L L S EKP+V + PQPR+ RD
Sbjct: 240 HTEAVFIELDDEFDIDDVREAMDKFRGLPQKLGLHSAPEKPVVVRDEENRPQPRMDRDMD 299
Query: 289 RGLTVTVGRLERTS---EGVKYVALGHNLVRGAAGGSVLNAEL 328
G+ VTVGRL + ++YV +GHN VRGAAG S+LNAEL
Sbjct: 300 GGMAVTVGRLREDAAFKNSLRYVLVGHNTVRGAAGASILNAEL 342
>pir||H72715 probable aspartate-semialdehyde dehydrogenase APE1143 - Aeropyrum
pernix (strain K1) >gi|5104813|dbj|BAA80128.1|
(AP000060) 349aa long hypothetical
aspartate-semialdehyde dehydrogenase [Aeropyrum pernix]
Length = 349
Score = 265 bits (669), Expect = 7e-70
Identities = 157/341 (46%), Positives = 223/341 (65%), Gaps = 16/341 (4%)
Query: 3 RVAVLGATGLVGRTFVKLLGGHPWFKVEKLIASEKSAGKKYGDLVE----DSPEEFRDYY 58
R AVLGA+GLVG+ F++LL GHP+F+V + +S AG + ++ P + +
Sbjct: 2 RAAVLGASGLVGQVFLRLLEGHPYFEVAAVASSPGKAGLDAAEAIDWILPGGPPGYLEGM 61
Query: 59 VISLNE--FLENPGVDLVFNALPASISRDVEEKLAQE-IPVFTNARAHRYDEDVPILVPE 115
+S E L GV+LVF+ALP+ + ++E LA+E VF+N+ R D D+P++ E
Sbjct: 62 RMSRPEPGALRAEGVELVFSALPSQAAAELEPALAREGFEVFSNSSNMRLDPDIPLVNGE 121
Query: 116 VNKDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRNF-GIKKVRVATMQAISGA 174
VN HL L + QR+R GW+G +V NPNC+TAILTL+L P+ + G+++V VATMQAISGA
Sbjct: 122 VNPGHLALAKAQRER-GWRGVVVKNPNCTTAILTLALKPIVDAAGLREVHVATMQAISGA 180
Query: 175 GFSGLSAYAIQDNVIPFISGEEWKIENESKKIMGKLKGDEIEPASFDVIAIATRVPVIHG 234
G G+ Y I DN+IP I GEE K+E ES+KI+G L+G +EPA+F V A TRVPV+ G
Sbjct: 181 GRRGVPGYGIVDNIIPHIPGEEGKVEAESRKILGSLRGGRLEPAAFSVAATTTRVPVLEG 240
Query: 235 HTEAVFVELENP-DIKSIREAIENFDPL-KDLKLPSY-EKPIVY---TEIPQPRLHRDRG 288
H E V+++ P + EA+E++ + ++L LP+ KP+ + PQPRL R G
Sbjct: 241 HLEVVYLKTARPMEPGEAVEALESYRGIPQELGLPTAPPKPLRVLRGEDRPQPRLDRAAG 300
Query: 289 RGLTVTVGRLERTSEG-VKYVALGHNLVRGAAGGSVLNAEL 328
G+TV+VGR+E G ++ V LGHNLVRGAAG ++L AEL
Sbjct: 301 GGMTVSVGRVEAKEGGWLRMVVLGHNLVRGAAGAALLAAEL 341
>gb|AAG19747.1| (AE005060) aspartate-semialdehyde dehydrogenase; Asd [Halobacterium
sp. NRC-1]
Length = 343
Score = 259 bits (654), Expect = 4e-68
Identities = 147/338 (43%), Positives = 198/338 (58%), Gaps = 12/338 (3%)
Query: 1 MKRVAVLGATGLVGRTFVKLLGGHPWFKVEKLIASEKSAGKKYGD-----LVEDSPEEFR 55
M V VLGATG VG+ FV+LL GH F++ + AS SAG+ Y D L PE
Sbjct: 1 MTTVGVLGATGAVGQRFVQLLAGHETFELSVVTASPDSAGETYRDAANWGLDTPVPESIA 60
Query: 56 DYYVISLNEFLENPGVDLVFNALPASISRDVEEKLAQE-IPVFTNARAHRYDEDVPILVP 114
+ V L+F+ALP+ + +VE L + V +NA R DVP++VP
Sbjct: 61 ELPVQPTTPAAIPDDTALLFSALPSDVGAEVEPALCEAGFVVSSNASNERRAGDVPLVVP 120
Query: 115 EVNKDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRNFGIKKVRVATMQAISGA 174
EVN DHL L++VQR RGW G +V NPNCST + +LA L FG+ +V VAT+QA+SGA
Sbjct: 121 EVNADHLGLIDVQRDARGWDGALVKNPNCSTITMVPTLAALTEFGLDRVHVATLQAVSGA 180
Query: 175 GFSGLSAYAIQDNVIPFISGEEWKIENESKKIMGKLKGDEIEPASFDVIAIATRVPVIHG 234
G+SG+++ I DNV+P I GEE K+E ES+K++G+ G E++ V A RVP + G
Sbjct: 181 GYSGVTSMEILDNVVPHIGGEERKMETESRKLLGEFTGAEVQHHDAVVSASCNRVPTLDG 240
Query: 235 HTEAVFVELENPDIKSIREAIENFDPLKDLKLPSYEKPIVYT----EIPQPRLHRDRGRG 290
H E VFV E D + + F+ L LPS P++ T E PQPRL R RG G
Sbjct: 241 HLENVFV--ETSDHPAPADVAAAFEDAPTLDLPSAPDPLIETFTAPERPQPRLDRMRGDG 298
Query: 291 LTVTVGRLERTSEGVKYVALGHNLVRGAAGGSVLNAEL 328
+ + G ++ T G++Y L HN +RGAAG S+LN EL
Sbjct: 299 MAIAAGGIQTTDTGIQYNCLAHNTIRGAAGASILNGEL 336
>gb|AAK41162.1| Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (asd-1)
[Sulfolobus solfataricus]
Length = 350
Score = 230 bits (581), Expect = 2e-59
Identities = 135/343 (39%), Positives = 210/343 (60%), Gaps = 14/343 (4%)
Query: 3 RVAVLGATGLVGRTFVKLLGGHPWFKVEKLIASEKSAGKKYGDLVE-----DSPEEFRDY 57
+V++LG+TG+VG+ V++L HP+ ++ K+ AS + GKKY D V+ D PE +
Sbjct: 6 KVSLLGSTGMVGQKMVRMLSKHPYIELVKVSASPQKIGKKYKDAVKWIEPGDIPENVAEL 65
Query: 58 YVISLNEFLENPGVDLVFNALPASISRDVEEKLAQEIP-VFTNARAHRYDEDVPILVPEV 116
++S E+ ++ VD+V +ALP ++ DVE KL ++ V +NA R D DVP++ PEV
Sbjct: 66 PIVS-TEYEDHKDVDVVLSALPNELAEDVELKLVKQGKIVVSNASPFRMDPDVPLINPEV 124
Query: 117 NKDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPL-RNFGIKKVRVATMQAISGAG 175
N +HL+L++ Q+ + W G +V NPNC+ AIL++ + PL R I + T+QA+SGAG
Sbjct: 125 NWEHLELLKYQKSSKNWNGLLVKNPNCTAAILSMPIKPLERLIKINATYIVTLQAVSGAG 184
Query: 176 FSGLSAYAIQDNVIPFISGEEWKIENESKKIMGKLKGDEIEPASFDVIAIATRVPVIHGH 235
+SGL AI NV+P+I GEE KI E K++GK + +++ +S ++ TRVPV GH
Sbjct: 185 YSGLPFMAIDGNVVPWIKGEEEKIPKEINKMLGKFEAGKLKSSSLEIHPTTTRVPVKVGH 244
Query: 236 TEAV-FVELENPDIKSIREAIENFDPLKDLK-LPSY-EKPIVY---TEIPQPRLHRDRGR 289
+ V +N D K +++A+++F L K LP+ KPI+ + PQP
Sbjct: 245 MGVINIVTDDNVDEKEVQKALDSFASLPQHKNLPTAPNKPIIVFKDEDRPQPARDLQYYD 304
Query: 290 GLTVTVGRLERTSEGVKYVALGHNLVRGAAGGSVLNAELAYKL 332
G+ VTVGR++ ++ V LG NLVRGAAG ++L E+ +L
Sbjct: 305 GMAVTVGRVKFEGNVLRLVVLGDNLVRGAAGITILTLEVMKEL 347
>sp|P41394|DHAS_LEPIN ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA DEHYDROGENASE) (ASADH)
>gi|321680|pir||A44846 aspartate-semialdehyde
dehydrogenase (EC 1.2.1.11) - Leptospira interrogans
>gi|149613|gb|AAA25262.1| (M77500) aspartate
beta-semialdehyde dehydrogenase [Leptospira
borgpetersenii] >gi|248278|gb|AAB21985.1| (S92223)
aspartate beta-semialdehyde dehydrogenase {EC 1.2.1.11}
[Leptospira interrogans, serovar icterohaemorrhagiae,
Peptide, 349 aa]
Length = 349
Score = 226 bits (569), Expect = 4e-58
Identities = 142/348 (40%), Positives = 203/348 (57%), Gaps = 19/348 (5%)
Query: 3 RVAVLGATGLVGRTFVKLLGGHPWFKVEKLIASEKSAGKKYGDLVEDSPEEFRDYYVISL 62
+VAVLGATG VG+ F++LL HP+F++ L ASE SAGK YG++++ + D +
Sbjct: 5 KVAVLGATGSVGQRFIQLLDHHPFFEITHLCASENSAGKTYGEVMKTRWKISSDIPAYAK 64
Query: 63 NEFLENPG------VDLVFNALPASISRDVEEKLAQE-IPVFTNARAHRYDEDVPILVPE 115
N + P V L F+ L ++++ +VE+ A I + +N++ HR D VPIL E
Sbjct: 65 NLVITTPDPAKTKDVVLAFSGLDSNVAGEVEKNYANAGIHIISNSKNHRMDPTVPILSAE 124
Query: 116 VNKDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGA 174
VN HL+++ Q+ KG I+TN NC+ +T+SL PL + FGI+ V + +MQAISGA
Sbjct: 125 VNSSHLEVLTSQKT----KGKIITNSNCTIMGVTISLKPLLDRFGIESVMLFSMQAISGA 180
Query: 175 GFSGLSAYAIQDNVIPFISGEEWKIENESKKIMGKLKGDEIEPASFDVIAIATRVPVIHG 234
G+ G+ I NVIP I GEE K E E K +GK++ +I A F + A RVPV G
Sbjct: 181 GYPGVPTMDILGNVIPHIGGEEEKAEIEPLKCLGKVENGKILHADFSISAHCNRVPVFDG 240
Query: 235 HTEAVFVEL-ENPDIKSIREAIENFD-PLKDLKLPSYEKPIVY----TEIPQPRLHRDRG 288
HT V V+ + P + I + ++F + L LP P++ + PQPRL D G
Sbjct: 241 HTVCVSVKFKKKPSREEIISSWKDFSGEPQTLGLPLAPNPVILFREEEDRPQPRLDLDTG 300
Query: 289 RGLTVTVGRLERTS-EGVKYVALGHNLVRGAAGGSVLNAELAYKLKII 335
+G+T +GRL KYV L HN +RGAAG ++LNAEL YK K +
Sbjct: 301 KGMTTVIGRLRPDPILDWKYVVLSHNTIRGAAGAALLNAELLYKKKFL 348
>pir||T42373 probable aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) -
fission yeast (Schizosaccharomyces pombe) (fragment)
>gi|1749466|dbj|BAA13791.1| (D89129) similar to
Saccharomyces cerevisiae aspartate-semialdehyde
dehydrogenase, SWISS-PROT Accession Number P13663
[Schizosaccharomyces pombe]
Length = 355
Score = 206 bits (520), Expect = 2e-52
Identities = 140/355 (39%), Positives = 203/355 (56%), Gaps = 28/355 (7%)
Query: 1 MKRVAVLGATGLVGRTFVKLLGGHPWFKVEKLIASEKSAGKKYGDLVE-----DSPEEFR 55
+K+V +LGATG VG+ F+ LL HP FK+ L AS +SAGK Y + P+E
Sbjct: 1 IKKVGILGATGTVGQRFITLLSDHPEFKIAVLGASARSAGKPYAVATKWKQSIAMPKEIS 60
Query: 56 DYYVISLN--EFLENPGVDLVFNALPASISRDVEEKLAQ-EIPVFTNARAHRYDEDVPIL 112
V + + EF E D+VF+ L A + ++E+ + + +NA+ +R + VP++
Sbjct: 61 QMSVKACDPKEFSE---CDIVFSGLDADFAGEIEKSFRDANLVIVSNAKNYRREPTVPLV 117
Query: 113 VPEVNKDHLKLVEVQRKRRGW-KGFIVTNPNCSTAILTLSLAPLRN-FG-IKKVRVATMQ 169
VP VN DHL +++ QR+ +G I+TN NCSTA + + L L++ FG I + V +MQ
Sbjct: 118 VPTVNTDHLDVIKYQRQENKLDRGCIITNSNCSTAAVVVPLKALQDAFGPIAQTNVVSMQ 177
Query: 170 AISGAGFSGLSAYAIQDNVIPFISGEEWKIENESKKIMGKLKG--DEIEPASFDVIAIAT 227
AISGAG+ G+S+ I DN++PFI GEE KIE E++KI+G + E V A
Sbjct: 178 AISGAGYPGVSSLDILDNIVPFIGGEEEKIEWETRKILGSVNSTISGYELTDNVVSAQCN 237
Query: 228 RVPVIHGHTEAVFVEL--ENPDIKSIREAIENF--DPLKDLKLPSYEKPIVYT------E 277
RVPVI GH + V+ +P +RE + N+ +P K L S K +Y +
Sbjct: 238 RVPVIDGHLMCISVKFAKTSPTPDQVREVLANYVSEPQK-LGCYSAPKQAIYVFDDSTPD 296
Query: 278 IPQPRLHRDRGRGLTVTVGRLERTS-EGVKYVALGHNLVRGAAGGSVLNAELAYK 331
PQPRL R+ G V+VGR+ S +K+V+L HN V GAAG +LNAE+A K
Sbjct: 297 RPQPRLDRNNENGYAVSVGRIRSDSIFDIKFVSLVHNTVLGAAGAGILNAEVAVK 351
>pir||T41167 hypothetical protein SPCC1827.06c - fission yeast
(Schizosaccharomyces pombe) >gi|3184101|emb|CAA19314.1|
(AL023777) aspartate semialdehyde dehydrogenase.
[Schizosaccharomyces pombe]
Length = 357
Score = 206 bits (520), Expect = 2e-52
Identities = 140/355 (39%), Positives = 203/355 (56%), Gaps = 28/355 (7%)
Query: 1 MKRVAVLGATGLVGRTFVKLLGGHPWFKVEKLIASEKSAGKKYGDLVE-----DSPEEFR 55
+K+V +LGATG VG+ F+ LL HP FK+ L AS +SAGK Y + P+E
Sbjct: 3 IKKVGILGATGTVGQRFITLLSDHPEFKIAVLGASARSAGKPYAVATKWKQSIAMPKEIS 62
Query: 56 DYYVISLN--EFLENPGVDLVFNALPASISRDVEEKLAQ-EIPVFTNARAHRYDEDVPIL 112
V + + EF E D+VF+ L A + ++E+ + + +NA+ +R + VP++
Sbjct: 63 QMSVKACDPKEFSE---CDIVFSGLDADFAGEIEKSFRDANLVIVSNAKNYRREPTVPLV 119
Query: 113 VPEVNKDHLKLVEVQRKRRGW-KGFIVTNPNCSTAILTLSLAPLRN-FG-IKKVRVATMQ 169
VP VN DHL +++ QR+ +G I+TN NCSTA + + L L++ FG I + V +MQ
Sbjct: 120 VPTVNTDHLDVIKYQRQENKLDRGCIITNSNCSTAAVVVPLKALQDAFGPIAQTNVVSMQ 179
Query: 170 AISGAGFSGLSAYAIQDNVIPFISGEEWKIENESKKIMGKLKG--DEIEPASFDVIAIAT 227
AISGAG+ G+S+ I DN++PFI GEE KIE E++KI+G + E V A
Sbjct: 180 AISGAGYPGVSSLDILDNIVPFIGGEEEKIEWETRKILGSVNSTISGYELTDNVVSAQCN 239
Query: 228 RVPVIHGHTEAVFVEL--ENPDIKSIREAIENF--DPLKDLKLPSYEKPIVYT------E 277
RVPVI GH + V+ +P +RE + N+ +P K L S K +Y +
Sbjct: 240 RVPVIDGHLMCISVKFAKTSPTPDQVREVLANYVSEPQK-LGCYSAPKQAIYVFDDSTPD 298
Query: 278 IPQPRLHRDRGRGLTVTVGRLERTS-EGVKYVALGHNLVRGAAGGSVLNAELAYK 331
PQPRL R+ G V+VGR+ S +K+V+L HN V GAAG +LNAE+A K
Sbjct: 299 RPQPRLDRNNENGYAVSVGRIRSDSIFDIKFVSLVHNTVLGAAGAGILNAEVAVK 353
>emb|CAC11507.1| (AL445064) aspartate-semialdehyde dehydrogenase related protein
[Thermoplasma acidophilum]
Length = 338
Score = 199 bits (501), Expect = 4e-50
Identities = 136/349 (38%), Positives = 204/349 (57%), Gaps = 31/349 (8%)
Query: 3 RVAVLGATGLVGRTFVKLLGGHPWFKVEKLIASEKSAGKKYGDLVEDSPEE-FRDYYVIS 61
RV +LG+TG+VG K++ HP+F + + AS++SAG++YG++V + +R+ V
Sbjct: 5 RVGLLGSTGVVGSLLSKMIAIHPYFDLANVYASDRSAGQRYGNVVYGGASDLYRNLEVKE 64
Query: 62 LN-EFLENPGVDLVFNALPASISRDVEEKLAQE-IPVFTNARAHRYDEDVPILVPEVNKD 119
N + + + D++F+A+ + +E +LA+ +P+FTNA A+R ++DV ++VPE+N D
Sbjct: 65 SNPDRIISDHNDIIFSAVSDEKAGLIERRLAEAGLPIFTNASANRLEDDVFLIVPEINGD 124
Query: 120 HLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAP-LRNFGIKKVRVATMQAISGAGFSG 178
+ + KR KGFI+ N NCST L L + P +R K+ V TMQA+SGAG+ G
Sbjct: 125 LVGSI----KR---KGFIIANGNCSTIGLALGIDPVIRGRSAVKIIVTTMQAVSGAGYPG 177
Query: 179 LSAYAIQDNVIPFISGEEWKIENESKKIM-GKLKGDEIEPASFDVIAIATRVPVIHGHTE 237
+S+ I DN+IP+I EE KIE E+KKI GKL ++ A TRVPV GH E
Sbjct: 178 VSSLDIIDNMIPYIQKEETKIERETKKIFSGKL--------DTEIFATTTRVPVKIGHME 229
Query: 238 AVFVELENP-DIKSIREAIENFDP--LKDLKLPSYEKPIVYTE---IPQPRLHRDRG--- 288
+V +E + D IR ++ LK + ++ ++ E PQP L G
Sbjct: 230 SVHIEFDQVLDPSEIRAEFRSYGNGLLKTVYPSLPDRSVILLEKDDRPQPALDATNGGSA 289
Query: 289 --RGLTVTVGRLERTSEGVKYVALGHNLVRGAAGGSVLNAELAYKLKII 335
G+ V+VGRL S + V L +NLVRGAAG ++LNAE+AYK II
Sbjct: 290 LKAGMAVSVGRLRVRSRSLDLVLLVNNLVRGAAGSTLLNAEIAYKEGII 338
>gb|AAK42353.1| Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (asd-2)
[Sulfolobus solfataricus]
Length = 356
Score = 197 bits (495), Expect = 2e-49
Identities = 127/344 (36%), Positives = 203/344 (58%), Gaps = 21/344 (6%)
Query: 3 RVAVLGATGLVGRTFVKLLGGHPWFKVEKLIASEKSAGKKYGDLVE-----DSPEEFRDY 57
+ A+LG+TGLVG +V++L HP+ KV L A + S GK YG++V P E D
Sbjct: 6 KAAILGSTGLVGIEYVRMLANHPYIKVGYL-AGKGSVGKPYGEVVRWQTIGQVPTEIADM 64
Query: 58 YVISLNEFLENPGVDLVFNALPASISRDVEEKLAQE-IPVFTNARAHRYDEDVPILVPEV 116
V + L + VD+VF+ LP + VEE+ A+ PV +N+ HR+D DVP+L+PEV
Sbjct: 65 EVKPTDPKLMDD-VDIVFSPLPQGAAGPVEEEFAKHGFPVISNSPDHRFDPDVPLLIPEV 123
Query: 117 NKDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPL-RNFGIKKVRVATMQAISGAG 175
N + L++ QR+RR W+GFIVT P C+ + LAP+ NF I + T+Q++SGAG
Sbjct: 124 NPHTISLIDKQRERRDWRGFIVTTPLCTAQGAAIPLAPIYMNFKIDSSLITTIQSLSGAG 183
Query: 176 FSGLSAYAIQDNVIPFISGEEWKIENESKKIMGKLKG-DEIEPASFDVIAIATRVPVIHG 234
+ G+ + + DNV+P + K E +I+ + K + + + + A RV IHG
Sbjct: 184 YPGIPSLDVIDNVLPLGDNYDNKTVKEISRILSETKRMVDDDDNNLSLGATTHRVATIHG 243
Query: 235 HTEAVFVEL-ENPDIKSIREAIENF--DPLKDLKLPSY-EKPI-VYTEIPQPRLHRDRGR 289
H E +++ E+ ++ I E +++F +P ++LKLP+ +KPI + + +P+++ DR
Sbjct: 244 HYEVIYITFKEDVTVEKIGETLDSFRGEP-QNLKLPTAPDKPILLINQDARPQVYFDRWA 302
Query: 290 ----GLTVTVGRLERTS-EGVKYVALGHNLVRGAAGGSVLNAEL 328
G++V VGRL + + ++ V++ HN VRGAAGG +L EL
Sbjct: 303 GNPPGMSVVVGRLGQINRRTIRLVSVIHNTVRGAAGGGILATEL 346
>gb|AAB03213.1| (U44901) aspartate semialdehyde dehydrogenase [Ustilago maydis]
Length = 366
Score = 192 bits (483), Expect = 5e-48
Identities = 133/349 (38%), Positives = 197/349 (56%), Gaps = 22/349 (6%)
Query: 3 RVAVLGATGLVGRTFVKLLGGHPWFKVEKLIASEKSAGKKYGDLVEDSPEEFR----DYY 58
+V +LGATG VG+ + L HP F++ L AS SAGK Y + V+ ++ R +
Sbjct: 11 KVGLLGATGTVGQRIILQLADHPQFELAALGASSSSAGKPYLEAVQGRWKQIRRVPDNVA 70
Query: 59 VISLNEFLENPGVDLVFNALPASISRDVEEKLAQ-EIPVFTNARAHRYDEDVPILVPEVN 117
+ + E V + + + R VE+ + E+ VF+NA+ +R D P++VP VN
Sbjct: 71 QLPVYECKPEYFASAVVSPVWIQVQRTVEDAFRRAELRVFSNAKNYRTDPLCPLVVPLVN 130
Query: 118 KDHLKLVEVQRKRRGWK-GFIVTNPNCSTAILTLSLAPLR-NFG-IKKVRVATMQAISGA 174
+H++++ QR++ G K GFIVTN NCST + + L L FG ++K+ V TMQAISGA
Sbjct: 131 PEHMEILPFQRQQVGTKKGFIVTNANCSTTGIVVPLKALEAKFGPLEKILVNTMQAISGA 190
Query: 175 GFSGLSAYAIQDNVIPFISGEEWKIENESKKIMGKLKGDEI-----EPASFDVIAIATRV 229
G+ G+S+ I DNV+PFISGEE KIE E+ KI+G +K D+ E V A RV
Sbjct: 191 GYPGVSSLDILDNVVPFISGEEEKIEWETAKILGGIKTDKTAFDYHEEHPLKVSAHCNRV 250
Query: 230 PVIHGHTEAVFVELEN---PDIKSIREAIENF-DPLKDLKLPSYEKPIVYT----EIPQP 281
PVI GH E V V +N P + +++ ++ F + + + S K + + PQP
Sbjct: 251 PVIDGHMECVSVSFKNRPAPSVDEVKKCLQGFTTEAQTIGVHSAPKQAITVHEEQDRPQP 310
Query: 282 RLHRDRGRGLTVTVGRL-ERTSEGVKYVALGHNLVRGAAGGSVLNAELA 329
RL RD G V VGR+ E +K+V L +N++ GAA +NAE+A
Sbjct: 311 RLDRDWQNGAGVNVGRVRECPVFDIKFVVLSNNVMIGAATSWFMNAEIA 359
>gi|6320362 aspartic beta semi-aldehyde dehydrogenase; Hom2p [Saccharomyces
cerevisiae] >gi|118513|sp|P13663|DHAS_YEAST
ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA DEHYDROGENASE)
(ASA DH) >gi|82905|pir||JQ0198 aspartate-semialdehyde
dehydrogenase (EC 1.2.1.11) [validated] - yeast
(Saccharomyces cerevisiae) >gi|3795|emb|CAA33675.1|
(X15649) aspartic semi-aldehyde dehydrogenase (AA 1-365)
[Saccharomyces cerevisiae] >gi|899405|emb|CAA90378.1|
(Z50046) Hom2p [Saccharomyces cerevisiae]
Length = 365
Score = 190 bits (477), Expect = 2e-47
Identities = 142/366 (38%), Positives = 199/366 (53%), Gaps = 37/366 (10%)
Query: 2 KRVAVLGATGLVGRTFVKLLGGHPWFKVEKLIASEKSAGKKYGDLV-----EDSPEEFRD 56
K VLGATG VG+ F+ LL HP F+++ L AS +SAGKKY D V + PE D
Sbjct: 5 KIAGVLGATGSVGQRFILLLANHPHFELKVLGASSRSAGKKYVDAVNWKQTDLLPESATD 64
Query: 57 YYVISL-NEFLENPGVDLVFNALPASISRDVEEKLAQE-IPVFTNARAHRYDEDVPILVP 114
V +EF + D+VF+ L A + +E++ + I + +NA+ +R ++DVP++VP
Sbjct: 65 IIVSECKSEFFKE--CDIVFSGLDADYAGAIEKEFMEAGIAIVSNAKNYRREQDVPLIVP 122
Query: 115 EVNKDHLKLV-------EVQRKRRGWKGFIVTNPNCSTAILTLSLAPL-RNFG-IKKVRV 165
VN +HL +V + Q K R GFI+ NCSTA L L PL FG I +
Sbjct: 123 VVNPEHLDIVAQKLDTAKAQGKPR--PGFIICISNCSTAGLVAPLKPLIEKFGPIDALTT 180
Query: 166 ATMQAISGAGFS-GLSAYAIQDNVIPFISGEEWKIENESKKIMGKLKGDE-----IEPAS 219
T+QAISGAGFS G+ I DN+IP+I GEE K+E E+KKI+ L D+ + P
Sbjct: 181 TTLQAISGAGFSPGVPGIDILDNIIPYIGGEEDKMEWETKKILAPLAEDKTHVKLLTPEE 240
Query: 220 FDVIAIATRVPVIHGHTEAVFVELEN---PDIKSIREAIENF--DPLKDLKLPSYEKPIV 274
V A RV V GHTE + + +N P ++ ++ ++ + D K L S K +
Sbjct: 241 IKVSAQCNRVAVSDGHTECISLRFKNRPAPSVEQVKTCLKEYVCDAYK-LGCHSAPKQTI 299
Query: 275 YT----EIPQPRLHRDRGRGLTVTVGRL-ERTSEGVKYVALGHNLVRGAAGGSVLNAELA 329
+ + PQPRL R+R G V+VGR+ E K V L HN + GAAG VL AE+
Sbjct: 300 HVLEQPDRPQPRLDRNRDSGYGVSVGRIREDPLLDFKMVVLSHNTIIGAAGSGVLIAEIL 359
Query: 330 YKLKII 335
+I
Sbjct: 360 LARNLI 365
>pir||H71524 probable aspartate dehydrogenase - Chlamydia trachomatis (serotype
D, strain UW3/Cx) >gi|3328786|gb|AAC67959.1| (AE001309)
Aspartate semialdehyde dehydrogenase [Chlamydia
trachomatis]
Length = 334
Score = 168 bits (422), Expect = 7e-41
Identities = 120/335 (35%), Positives = 177/335 (52%), Gaps = 29/335 (8%)
Query: 3 RVAVLGATGLVGRTFVKLLGGHPWFKVEKLIASEKSAGKKYGDL------VEDSPEEFRD 56
R+A+LGATGLVG+ + LL H +++ +L AS + +Y + PE RD
Sbjct: 4 RIAILGATGLVGQKLIALLQNHKQWEIAELGASSEKHALRYESACLWQEPLMGMPESVRD 63
Query: 57 YYVISLNEFLENPGVDLVFNALPASISRDVEEK-LAQEIPVFTNARAHRYDEDVPILVPE 115
+ S+ E N +V + LP+S++ E L+ VF+NA A+R + VPIL+PE
Sbjct: 64 LSIRSVEEIESN----IVVSCLPSSVAFSAETTCLSSGKIVFSNATAYRMHKAVPILIPE 119
Query: 116 VNKDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRNFGIKKVRVATMQAISGAG 175
+N DHL L+E Q + G I+TN NC + + L+L PL F I+ V V T+Q+ SGAG
Sbjct: 120 INSDHLSLLEEQP----FLGKIITNSNCCVSGIALALKPLLLFNIEHVHVITLQSASGAG 175
Query: 176 FSGLSAYAIQDNVIPFISGEEWKIENESKKIMGKLKGDEIEPASFDVIAIATRVPVIHGH 235
+ G+S+ + N +P+I GEE KI E+ KI+G+ PA F + A RVPV HGH
Sbjct: 176 YPGVSSLDLIGNTVPYILGEEEKILRETVKILGQ----PGFPAEFSITASVHRVPVAHGH 231
Query: 236 TEAVFVELENP-DIKSIREAIENFDPLKDLKLPSYEKPIVYTEIPQPRLHRDRGRGL-TV 293
+V V + D++ I E L Y+ P + ++ + H D + +
Sbjct: 232 VISVHVMFDQEVDLEEITSCYEKDSATYVL----YDSP-WHPQVRKDLAHDDMRLHIGPI 286
Query: 294 TVGRLERTSEGVKYVALGHNLVRGAAGGSVLNAEL 328
+ G RT +K L HNLVRGAAG + N L
Sbjct: 287 SYGGNTRT---IKMCILLHNLVRGAAGALIANMNL 318
>pir||G72002 aspartate dehydrogenase - Chlamydophila pneumoniae (strain CWL029)
>gi|4377382|gb|AAD19185.1| (AE001685) Aspartate
Dehydrogenase [Chlamydophila pneumoniae CWL029]
>gi|8163501|gb|AAF73704.1| (AE002239)
aspartate-semialdehyde dehydrogenase [Chlamydophila
pneumoniae AR39]
Length = 333
Score = 166 bits (416), Expect = 3e-40
Identities = 117/337 (34%), Positives = 177/337 (51%), Gaps = 31/337 (9%)
Query: 3 RVAVLGATGLVGRTFVKLLGGHPWFK---VEKLIASEKSAGKKYGDL------VEDSPEE 53
R+AVLG TGLVG+ FV LL H W++ + +++AS G+ YGD + PE
Sbjct: 2 RIAVLGVTGLVGQKFVALL--HKWYRDWVIAEVVASNSKYGQSYGDACIWQEPIGPMPEM 59
Query: 54 FRDYYVISLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILV 113
RD + + E D+V + LP+S L+Q VF+NA +R VPI++
Sbjct: 60 VRDLPIRKIEEVQS----DIVVSFLPSSAESMEAYCLSQGKVVFSNASTYRMHSSVPIII 115
Query: 114 PEVNKDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRNFGIKKVRVATMQAISG 173
PEVN DH +L+E Q + G I+T+PNC + +TL+LAPLR F + V + T+Q+ SG
Sbjct: 116 PEVNSDHFQLLEEQP----YPGKIITSPNCCVSGITLALAPLRKFSLDHVHIVTLQSASG 171
Query: 174 AGFSGLSAYAIQDNVIPFISGEEWKIENESKKIMGKLKGDEIEPASFDVIAIATRVPVIH 233
AG+ G+ + + N +P I GEE KI E+ KI+G K +P + RVPV +
Sbjct: 172 AGYPGVPSLDLLANTVPHIVGEEEKILRETVKILGSSK----QPLPCKLSVTVHRVPVAY 227
Query: 234 GHTEAVFVEL-ENPDIKSIREAIENFDPLKDLKLPSYEKPIVYTEIPQPRLHRDRGRGLT 292
GHT ++ V ++ D+ I + + K+ + P+ + PQ R H +
Sbjct: 228 GHTLSLHVTFSKDVDLDEILYSYQE----KNKEFPNTYQLYDNPWSPQARKHLSHD-DMR 282
Query: 293 VTVGRLERTSE--GVKYVALGHNLVRGAAGGSVLNAE 327
V +G + + +K L HNLVRGAAG + + E
Sbjct: 283 VHLGPITYGGDFRTIKMNVLIHNLVRGAAGTLLASME 319
>dbj|BAA99255.1| (AP002548) aspartate dehydrogenase [Chlamydophila pneumoniae J138]
Length = 333
Score = 165 bits (414), Expect = 6e-40
Identities = 117/337 (34%), Positives = 177/337 (51%), Gaps = 31/337 (9%)
Query: 3 RVAVLGATGLVGRTFVKLLGGHPWFK---VEKLIASEKSAGKKYGDL------VEDSPEE 53
R+AVLG TGLVG+ FV LL H W++ + +++AS G+ YGD + PE
Sbjct: 2 RIAVLGVTGLVGQKFVALL--HKWYRDWVIAEVVASNSKYGQSYGDACIWQEPIGPMPEM 59
Query: 54 FRDYYVISLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILV 113
RD + + E D+V + LP+S L+Q VF+NA +R VPI++
Sbjct: 60 VRDLPIRKIEEVQS----DIVDSFLPSSAESMEAYCLSQGKVVFSNASTYRMHSSVPIII 115
Query: 114 PEVNKDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRNFGIKKVRVATMQAISG 173
PEVN DH +L+E Q + G I+T+PNC + +TL+LAPLR F + V + T+Q+ SG
Sbjct: 116 PEVNSDHFQLLEEQP----YPGKIITSPNCCVSGITLALAPLRKFSLDHVHIVTLQSASG 171
Query: 174 AGFSGLSAYAIQDNVIPFISGEEWKIENESKKIMGKLKGDEIEPASFDVIAIATRVPVIH 233
AG+ G+ + + N +P I GEE KI E+ KI+G K +P + RVPV +
Sbjct: 172 AGYPGVPSLDLLANTVPHIVGEEEKILRETVKILGSSK----QPLPCKLSVTVHRVPVAY 227
Query: 234 GHTEAVFVEL-ENPDIKSIREAIENFDPLKDLKLPSYEKPIVYTEIPQPRLHRDRGRGLT 292
GHT ++ V ++ D+ I + + K+ + P+ + PQ R H +
Sbjct: 228 GHTLSLHVTFSKDVDLDEILYSYQE----KNKEFPNTYQLYDNPWSPQARKHLSHD-DMR 282
Query: 293 VTVGRLERTSE--GVKYVALGHNLVRGAAGGSVLNAE 327
V +G + + +K L HNLVRGAAG + + E
Sbjct: 283 VHLGPITYGGDFRTIKMNVLIHNLVRGAAGTLLASME 319
>gb|AAF73580.1| (AE002332) aspartate-semialdehyde dehydrogenase [Chlamydia
muridarum]
Length = 334
Score = 165 bits (413), Expect = 8e-40
Identities = 116/333 (34%), Positives = 177/333 (52%), Gaps = 31/333 (9%)
Query: 3 RVAVLGATGLVGRTFVKLLGGHPWFKVEKLIASEKSAGKKYGDL------VEDSPEEFRD 56
R+A+LGATGLVG+ + LL H +++ +L AS K +Y + PE +D
Sbjct: 4 RIAILGATGLVGQKLIALLQRHKQWEIAELSASPKKHSLRYESACLWQEPLMAMPESVQD 63
Query: 57 YYVISLNEFLENPGVDLVFNALPASISRDVEEK-LAQEIPVFTNARAHRYDEDVPILVPE 115
+ S+ E D+V + LP S++ E L+ VF+N+ A+R E VPIL+PE
Sbjct: 64 LTIRSIEEIES----DIVVSCLPTSVAFSAETACLSSGKIVFSNSGAYRMHESVPILIPE 119
Query: 116 VNKDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRNFGIKKVRVATMQAISGAG 175
VN DH+ L++ Q + G IVTN NC + + L+L PL F I+ V V T+Q+ SGAG
Sbjct: 120 VNSDHISLLDDQP----FLGKIVTNSNCCVSGIALALRPLLPFDIEHVHVVTLQSASGAG 175
Query: 176 FSGLSAYAIQDNVIPFISGEEWKIENESKKIMGKLKGDEIEPASFDVIAIATRVPVIHGH 235
+ G+S+ + N IP I GEE KI E+ KI+ G PA F + A RVPV++GH
Sbjct: 176 YPGVSSLDLIGNTIPHILGEEEKIHQETLKIL----GSPSSPAEFSITASVHRVPVMYGH 231
Query: 236 TEAVFVEL-ENPDIKSIREAIENFDPLKDLKLPSYEKPIVYTEIPQPRLHRDRGRGLTVT 294
++ V + ++ I E + L Y+ P + ++ + LH D + +
Sbjct: 232 VISMHVMFAQEVSLEKIFCCYEKYSDTYVL----YDSP-WHPQVQKDLLHDD----MRLH 282
Query: 295 VGRLER--TSEGVKYVALGHNLVRGAAGGSVLN 325
+G + +++ +K L HNLVRGAAG + N
Sbjct: 283 IGPISHGGSAKTIKMCVLLHNLVRGAAGALISN 315
>sp|O67716|DHAS_AQUAE ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA DEHYDROGENASE) (ASADH)
>gi|7431495|pir||B70461 aspartate-semialdehyde
dehydrogenase (EC 1.2.1.11) - Aquifex aeolicus
>gi|2984139|gb|AAC07674.1| (AE000760)
aspartate-semialdehyde dehydrogenase [Aquifex aeolicus]
Length = 340
Score = 123 bits (306), Expect = 3e-27
Identities = 114/370 (30%), Positives = 179/370 (47%), Gaps = 70/370 (18%)
Query: 3 RVAVLGATGLVGRTFVKLLGGHPWFKVEKLI--ASEKSAGKKYGDLVEDSPEEFRDYYVI 60
RVA++GATG VGRTF+K+L F V++L+ ASE+S GK + ++Y V
Sbjct: 4 RVAIVGATGEVGRTFLKVLEERN-FPVDELVLYASERSEGKVL-------TFKGKEYTVK 55
Query: 61 SLNEFLENPGVDLVFNALPASISRDVEEKLAQE-IPVFTNARAHRYDEDVPILVPEVNKD 119
+LN+ G+D+ + S S++ K A++ + V N+ A R D DVP++VPEVN +
Sbjct: 56 ALNKENSFKGIDIALFSAGGSTSKEWAPKFAKDGVVVIDNSSAWRMDPDVPLVVPEVNPE 115
Query: 120 HLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGAGFSG 178
+K K++G I+ NPNCST + ++L P+ + GIK+V V+T QA+SGAG
Sbjct: 116 DVK----DFKKKG----IIANPNCSTIQMVVALKPIYDKAGIKRVVVSTYQAVSGAGAKA 167
Query: 179 LS---------------------AYAIQDNVIPFI--------SGEEWKIENESKKIMGK 209
+ + I N +P I + EE K+ E++KIM
Sbjct: 168 IEDLKNQTKAWCEGKEMPKAQKFPHQIAFNALPHIDVFFEDGYTKEENKMLYETRKIM-- 225
Query: 210 LKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP-DIKSIREAIENFDPLKDLKLPS 268
+ V A R+PV +GH+E++ +E E + RE ++N + + P
Sbjct: 226 ------HDENIKVSATCVRIPVFYGHSESISMETEKEISPEEAREVLKNAPGVIVIDNPQ 279
Query: 269 YEKPIVYTEIPQPRLHRDRGRGLTVTVGRLERT---SEGVKYVALGHNLVRGAAGGSVLN 325
E P P + R V VGR+ + G+ + N+ +GAA +V
Sbjct: 280 ------NNEYPMPIMAEGRDE---VFVGRIRKDRVFEPGLSMWVVADNIRKGAATNAVQI 330
Query: 326 AELAYKLKII 335
AEL K +I
Sbjct: 331 AELLVKEGLI 340
>pir||D72246 aspartate-semialdehyde dehydrogenase - Thermotoga maritima (strain
MSB8) >gi|4982089|gb|AAD36590.1|AE001799_22 (AE001799)
aspartate-semialdehyde dehydrogenase [Thermotoga
maritima]
Length = 327
Score = 116 bits (288), Expect = 3e-25
Identities = 97/281 (34%), Positives = 142/281 (50%), Gaps = 53/281 (18%)
Query: 3 RVAVLGATGLVGRTFVKLLGGHPWFKVE-KLIASEKSAGKKYGDLVEDSPEEFRDYYVIS 61
+V V+GATG VGRT VK+L E +L ASE+S GK+ +E E+F+ V
Sbjct: 4 KVGVVGATGEVGRTMVKVLEEFNVPVTELRLFASERSVGKE----IEFKGEKFK---VEL 56
Query: 62 LNEFLENPGVDLVFNALPASISRDVEEKLAQE-IPVFTNARAHRYDEDVPILVPEVNKDH 120
L E D + AS+SR A+ + V N+ A R ++++P++VPEVN
Sbjct: 57 LTEESMKWKCDYFLFSAGASVSRKFAPIAAENGVTVIDNSSAFRMEKEIPLVVPEVNAYL 116
Query: 121 LKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGAGFSGL 179
LK G+ G I+ NPNCST + LS+ L +GI+++ V+T Q++SGAG G+
Sbjct: 117 LK---------GYTG-IIANPNCSTIQMILSIYKLHEVYGIEEIFVSTYQSVSGAGHKGI 166
Query: 180 SAYAIQD---------------NVIPFI--------SGEEWKIENESKKIMGKLKGDEIE 216
Q+ NVIP I S EE K+ NE++KI+
Sbjct: 167 EELLAQERGENVMKVFPKPIHRNVIPLIGDIQENLFSQEEMKMVNETRKILNDY------ 220
Query: 217 PASFDVIAIATRVPVIHGHTEAVFVELENP--DIKSIREAI 255
S V RVPV++GH+EA+ V L+ P ++ +RE I
Sbjct: 221 --SIRVYPTTVRVPVLYGHSEAIMVRLKKPYESLEKVREVI 259
>pir||E75326 aspartate-semialdehyde dehydrogenase - Deinococcus radiodurans
(strain R1) >gi|6459794|gb|AAF11555.1|AE002038_4
(AE002038) aspartate-semialdehyde dehydrogenase
[Deinococcus radiodurans]
Length = 338
Score = 115 bits (284), Expect = 1e-24
Identities = 114/360 (31%), Positives = 169/360 (46%), Gaps = 71/360 (19%)
Query: 3 RVAVLGATGLVGRTFVKLLGGHPW-FKVEKLIASEKSAGKKYGDLVEDSPEEFRDYYVIS 61
RVA++GATG VG +K+L F +L AS +SAG S EFR +
Sbjct: 2 RVAIVGATGAVGHELLKVLETSSLDFSELQLYASPRSAG---------STLEFRGQPLTV 52
Query: 62 LNEFLENPGVDLVFNALPASISRDVEEKLAQE-IPVFTNARAHRYDEDVPILVPEVNKDH 120
DLV + SIS++ + + V N+ A RYD+DVP++VPEVN +
Sbjct: 53 QATPDGALPADLVLASAGGSISKEKAPRWVEGGAVVIDNSSAFRYDDDVPLVVPEVNGE- 111
Query: 121 LKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPL-RNFGIKKVRVATMQAISGAGFSGL 179
G KG I+ NPNC+TAI +++AP+ R +G+K++ V+T QA SGAG G+
Sbjct: 112 --------AALGHKG-IIANPNCTTAIAVVAVAPIHRKYGVKRMIVSTYQATSGAGQKGM 162
Query: 180 S--------------------AYAIQDNVIPFI--------SGEEWKIENESKKIMGKLK 211
+ I NVIP I + EE K+ E++KIM
Sbjct: 163 DELLTETHKVLHGQDAGHHEFVHPIPFNVIPHIDVFQDNGYTKEEMKVVWETRKIM---- 218
Query: 212 GDEIEPASFDVIAIATRVPVIHGHTEAVFVELENPDI-KSIREAIENFDPLKDLKLPSYE 270
GDE S + A R+P + H+EA+ +ELE P ++IRE + ++ PS +
Sbjct: 219 GDE----SLQISCTAVRIPTLRTHSEAITLELERPATPEAIRELLATAAGVEVRDDPSAK 274
Query: 271 KPIVYTEIPQPRLHRDRGRGLTVTVGRLERT---SEGVKYVALGHNLVRGAAGGSVLNAE 327
P P + V VGR+ ++ G++ G L++GAA +V AE
Sbjct: 275 L------YPMPLTASGK---YDVEVGRIRQSLVFDGGIELFVAGDQLLKGAALNAVQIAE 325
>dbj|BAB06120.1| (AP001515) aspartate-semialdehyde dehydrogenase [Bacillus
halodurans]
Length = 349
Score = 109 bits (269), Expect = 6e-23
Identities = 111/382 (29%), Positives = 167/382 (43%), Gaps = 92/382 (24%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVE-KLIASEKSAGKKYG------DLVEDSPEEFRD 56
VAV+GATG VG+ +K L + + KL++S++SAGK + E +PE F
Sbjct: 9 VAVVGATGAVGQQMLKTLEERNFPVGQLKLLSSKRSAGKTITFKGEPYTVEEATPEAFE- 67
Query: 57 YYVISLNEFLENPGVDLVFNALPASISRD-VEEKLAQEIPVFTNARAHRYDEDVPILVPE 115
GV + + S+S+ V E + + N A R D +VP++VPE
Sbjct: 68 -------------GVQIALFSAGGSVSKKLVPEAIKRGAICVDNTSAFRMDPEVPLVVPE 114
Query: 116 VNKDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLR-NFGIKKVRVATMQAISGA 174
VN++ +K G ++ NPNCST + ++L P+R +G+KKV V+T QA+SGA
Sbjct: 115 VNEEDVK------SHNG----VIANPNCSTIQMVVALEPIRQKYGLKKVIVSTYQAVSGA 164
Query: 175 GFSGLSA---------------------------YAIQDNVIPFI--------SGEEWKI 199
G + Y I N IP I + EE K+
Sbjct: 165 GLEAIEEMKTQTKEVLEGNEVNPEILPVGGDKKHYQIAFNAIPQIDLFQDNGFTFEEMKM 224
Query: 200 ENESKKIMGKLKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELE--NPDIKSIREAIEN 257
NE+KKIM +V A R+PV GH+E+V+ E E + ++ +E
Sbjct: 225 INETKKIM--------HMPELEVAATCVRLPVETGHSESVYFETEQGGASVSELKGLLET 276
Query: 258 FDPLKDLKLPSYE-KPIVYTEIPQPRLHRDRGRGLTVTVGRLER---TSEGVKYVALGHN 313
+ PS + P+ + +P V VGRL R G + N
Sbjct: 277 APGITVQDNPSEQLYPMAIHAVGKP----------DVFVGRLRRDLDRDNGYHMWVVSDN 326
Query: 314 LVRGAAGGSVLNAELAYKLKII 335
L++GAA SV AE KL ++
Sbjct: 327 LLKGAAWNSVQIAESLVKLGLV 348
>pir||G82690 aspartate-B-semialdehyde dehydrogenase XF1371 [imported] - Xylella
fastidiosa (strain 9a5c)
>gi|9106374|gb|AAF84180.1|AE003968_11 (AE003968)
aspartate-B-semialdehyde dehydrogenase [Xylella
fastidiosa]
Length = 344
Score = 106 bits (261), Expect = 5e-22
Identities = 109/364 (29%), Positives = 161/364 (43%), Gaps = 76/364 (20%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKLI--ASEKSAGKKYGDLVEDSPEEFRDYYVIS 61
+A++GATG VG + +L F V KLI AS +SAG + E V+
Sbjct: 12 IAIVGATGAVGEAMLSILEERH-FPVAKLIPLASARSAGSQITFKGES-------INVLE 63
Query: 62 LNEFLENPGVDLVFNALPASISRDVEEKLAQE-IPVFTNARAHRYDEDVPILVPEVNKDH 120
L F + GVD+ + + +S K A + V N+ A RY+EDVP++V EVN
Sbjct: 64 LEHF-DPHGVDIALFSAGSRVSEAYAPKFAAAGVVVIDNSSAFRYEEDVPLVVSEVNPHA 122
Query: 121 LKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPL-RNFGIKKVRVATMQAISGAGFSGL 179
LK QR R I+ NPNCST L LAP+ R + I+++ VAT Q++SG G S L
Sbjct: 123 LK----QRPRG-----IIANPNCSTMQLMPVLAPIHREYRIERINVATYQSVSGGGRSAL 173
Query: 180 SAYAIQD--------------------NVIPFI--------SGEEWKIENESKKIMGKLK 211
Q N+IP I + EE K+ E+KKI
Sbjct: 174 EELGQQTAQLLAFKEINPQRFPVQIAFNLIPHIDDFQSNGYTKEEMKLIWETKKI----- 228
Query: 212 GDEIEPASFDVIAIATRVPVIHGHTEAVFVELEN----PDIKSIREAIENFDPLKDLKLP 267
+E +S V A RVPV GH+EAV +E + +++ + + + + +
Sbjct: 229 ---LEDSSIQVNPTAVRVPVFFGHSEAVNIETQKKVTPEQARALLASAPGVEVVDEWQPG 285
Query: 268 SYEKPIVYTEIPQPRLHRDRGRGLTVTVGRLERT---SEGVKYVALGHNLVRGAAGGSVL 324
Y P+ + P V VGR+ G+ + N+ +GAA ++
Sbjct: 286 GYPTPVTHASGKDP-----------VFVGRIREDLSHPRGLNLWVVADNIRKGAALNAIQ 334
Query: 325 NAEL 328
AEL
Sbjct: 335 LAEL 338
>sp|Q04797|DHAS_BACSU ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA DEHYDROGENASE) (ASADH)
>gi|7427717|pir||F69590 aspartate-semialdehyde
dehydrogenase (EC 1.2.1.11) - Bacillus subtilis
>gi|142828|gb|AAA22383.1| (L08471) aspartate
semialdehyde dehydrogenase [Bacillus subtilis]
>gi|2634047|emb|CAB13548.1| (Z99112)
aspartate-semialdehyde dehydrogenase [Bacillus subtilis]
Length = 346
Score = 106 bits (261), Expect = 5e-22
Identities = 110/383 (28%), Positives = 167/383 (42%), Gaps = 94/383 (24%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPW-FKVEKLIASEKSAGKKYG------DLVEDSPEEFRD 56
VAV+GATG VG+ +K L + L++S++SAG K + E SPE F
Sbjct: 7 VAVVGATGAVGQQMLKTLEDRNFEMDTLTLLSSKRSAGTKVTFKGQELTVQEASPESFE- 65
Query: 57 YYVISLNEFLENPGVDLVFNALPASISRDVE-EKLAQEIPVFTNARAHRYDEDVPILVPE 115
GV++ + S+S+ + E + + V N A R DE+ P++VPE
Sbjct: 66 -------------GVNIALFSAGGSVSQALAPEAVKRGAIVIDNTSAFRMDENTPLVVPE 112
Query: 116 VNKDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGA 174
VN+ L + G I+ NPNCST + +L P+R +G+ KV V+T QA+SGA
Sbjct: 113 VNEADL------HEHNG----IIANPNCSTIQMVAALEPIRKAYGLNKVIVSTYQAVSGA 162
Query: 175 GFSGLSA---------------------------YAIQDNVIPFI--------SGEEWKI 199
G + Y I N IP I + EE K+
Sbjct: 163 GNEAVKELYSQTQAILNKEEIEPEIMPVKGDKKHYQIAFNAIPQIDKFQDNGYTFEEMKM 222
Query: 200 ENESKKIMGKLKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENPDIKSIREAIENFD 259
NE+KKIM V A R+P+ GH+E+V++E++ D
Sbjct: 223 INETKKIM--------HMPDLQVAATCVRLPIQTGHSESVYIEIDRDDA----------- 263
Query: 260 PLKDLKLPSYEKP-IVYTEIPQPRLH---RDRGRGLTVTVGRLER---TSEGVKYVALGH 312
++D+K E P + + P +L+ D V VGR+ + + G +
Sbjct: 264 TVEDIKNLLKEAPGVTLQDDPSQQLYPMPADAVGKNDVFVGRIRKDLDRANGFHLWVVSD 323
Query: 313 NLVRGAAGGSVLNAELAYKLKII 335
NL++GAA SV AE KL ++
Sbjct: 324 NLLKGAAWNSVQIAESLKKLNLV 346
>pir||D46665 aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) - Bacillus
subtilis
Length = 346
Score = 104 bits (258), Expect = 1e-21
Identities = 109/383 (28%), Positives = 167/383 (43%), Gaps = 94/383 (24%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPW-FKVEKLIASEKSAGKKYG------DLVEDSPEEFRD 56
VAV+GATG VG+ +K L + L++S+++AG K + E SPE F
Sbjct: 7 VAVVGATGAVGQQMLKTLEDRNFEMDTLTLLSSKRAAGTKVTFKGQELTVQEASPESFE- 65
Query: 57 YYVISLNEFLENPGVDLVFNALPASISRDVE-EKLAQEIPVFTNARAHRYDEDVPILVPE 115
GV++ + S+S+ + E + + V N A R DE+ P++VPE
Sbjct: 66 -------------GVNIALFSAGGSVSQALAPEAVKRGAIVIDNTSAFRMDENTPLVVPE 112
Query: 116 VNKDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGA 174
VN+ L + G I+ NPNCST + +L P+R +G+ KV V+T QA+SGA
Sbjct: 113 VNEADL------HEHNG----IIANPNCSTIQMVAALEPIRKAYGLNKVIVSTYQAVSGA 162
Query: 175 GFSGLSA---------------------------YAIQDNVIPFI--------SGEEWKI 199
G + Y I N IP I + EE K+
Sbjct: 163 GNEAVKELYSQTQAILNKEEIEPEIMPVKGDKKHYQIAFNAIPQIDKFQDNGYTFEEMKM 222
Query: 200 ENESKKIMGKLKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENPDIKSIREAIENFD 259
NE+KKIM V A R+P+ GH+E+V++E++ D
Sbjct: 223 INETKKIM--------HMPDLQVAATCVRLPIQTGHSESVYIEIDRDDA----------- 263
Query: 260 PLKDLKLPSYEKP-IVYTEIPQPRLH---RDRGRGLTVTVGRLER---TSEGVKYVALGH 312
++D+K E P + + P +L+ D V VGR+ + + G +
Sbjct: 264 TVEDIKNLLKEAPGVTLQDDPSQQLYPMPADAVGKNDVFVGRIRKDLDRANGFHLWVVSD 323
Query: 313 NLVRGAAGGSVLNAELAYKLKII 335
NL++GAA SV AE KL ++
Sbjct: 324 NLLKGAAWNSVQIAESLKKLNLV 346
>sp|O25801|DHAS_HELPY ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA DEHYDROGENASE) (ASADH)
>gi|7427719|pir||E64668 aspartate-semialdehyde
dehydrogenase (EC 1.2.1.11) - Helicobacter pylori
(strain 26695) >gi|2314350|gb|AAD08235.1| (AE000625)
aspartate-semialdehyde dehydrogenase (asd) [Helicobacter
pylori 26695]
Length = 346
Score = 103 bits (255), Expect = 3e-21
Identities = 96/340 (28%), Positives = 151/340 (44%), Gaps = 78/340 (22%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKLI--ASEKSAGKKYGDLVEDSPEEFRDYYVI- 60
VA++GA+G VG+ +K L + +F ++K + AS +SAGKK +DY ++
Sbjct: 6 VAIVGASGAVGQELIKGLE-NSFFPIKKFVPLASTRSAGKKIKAFN-------KDYEILE 57
Query: 61 SLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNKDH 120
+ +E E +D+ F + S+S + ++ V N R ++DVP++VPE+N
Sbjct: 58 TTHEVFEREKIDIAFFSAGGSVSEEFATSASKTALVVDNTSFFRLNKDVPLVVPEINAKE 117
Query: 121 LKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLR-NFGIKKVRVATMQAISGAGFSGL 179
+ + I+ NPNCST +T L PL +F IK V V+T QA+SGAG G+
Sbjct: 118 IFNAPLN---------IIANPNCSTIQMTQILNPLHLHFKIKSVIVSTYQAVSGAGNKGI 168
Query: 180 S------------------------------AYAIQDNVIPFI--------SGEEWKIEN 201
AY I N I I + EE K+ +
Sbjct: 169 ESLKNELKTALECLEKDPTIDLNQVLQAGAFAYPIAFNAIAHIDTFKENGYTKEELKMLH 228
Query: 202 ESKKIMGKLKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP-DIKSIREAIENFDP 260
E+ KIMG F + A RVPV+ H+E++ + E D+K + E ++N
Sbjct: 229 ETHKIMG---------VDFPISATCVRVPVLRSHSESLSIAFEKEFDLKEVYEVLKNAPS 279
Query: 261 LKDLKLPSYEKPIVYTEIPQPRLHRDRGRGLTVTVGRLER 300
+ PS+ P H D +V +GRL +
Sbjct: 280 VAVCDDPSHN----LYPTPLKASHTD-----SVFIGRLRK 310
>sp|Q9ZK28|DHAS_HELPJ ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA DEHYDROGENASE) (ASADH)
>gi|7431501|pir||C71847 aspartate-semialdehyde
dehydrogenase - Helicobacter pylori (strain J99)
>gi|4155713|gb|AAD06695.1| (AE001539)
aspartate-semialdehyde dehydrogenase [Helicobacter
pylori J99]
Length = 346
Score = 103 bits (255), Expect = 3e-21
Identities = 87/297 (29%), Positives = 137/297 (45%), Gaps = 69/297 (23%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKLI--ASEKSAGKKYGDLVEDSPEEFRDYYVI- 60
VA++GA+G VG+ +K L + +F ++K + AS +SAGKK +DY ++
Sbjct: 6 VAIVGASGAVGQELIKGLE-NSFFPIKKFVPLASARSAGKKIRAFN-------KDYEILE 57
Query: 61 SLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNKDH 120
+ +E E +D+ F + S+S + ++ V N R ++DVP++VPE+N
Sbjct: 58 TTHEVFEKEEIDIAFFSAGGSVSEEFAISASKTALVIDNTSFFRLNKDVPLVVPEINAQE 117
Query: 121 LKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLR-NFGIKKVRVATMQAISGAGFSGL 179
+ + I+ NPNCST +T L PL +F IK V V+T QA+SGAG G+
Sbjct: 118 IFNAPLN---------IIANPNCSTIQMTQILNPLHLHFKIKSVIVSTYQAVSGAGNKGI 168
Query: 180 S------------------------------AYAIQDNVIPFI--------SGEEWKIEN 201
AY I N I I + EE K+ +
Sbjct: 169 ESLKNELKTALEHLEKDPAIDLNQVLQAGAFAYPIAFNAIAHIDTFKENGYTKEELKMVH 228
Query: 202 ESKKIMGKLKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP-DIKSIREAIEN 257
E+ KIMG F + A RVPV+ H+E++ + E D+K + E ++N
Sbjct: 229 ETHKIMG---------VDFPISATCVRVPVLRSHSESLSIAFEKEFDLKEVYEVLKN 276
>pir||S14523 aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) - Vibrio
cholerae >gi|48346|emb|CAA39048.1| (X55363)
aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
Length = 337
Score = 102 bits (253), Expect = 4e-21
Identities = 107/363 (29%), Positives = 160/363 (43%), Gaps = 76/363 (20%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKL--IASEKSAGKKY---GDLVEDSPEEFRDYY 58
VA+ GATG VG T +++L F V++L +ASE+S GK Y G V E D+
Sbjct: 7 VAIFGATGAVGETMLEVLQERE-FPVDELFLLASERSEGKTYRFNGKTVRVQNVEEFDWS 65
Query: 59 VISLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNK 118
+ + F + G +L P + V V N RYD D+P++VPEVN
Sbjct: 66 QVHIALF--SAGGELSAKWAPIAAEAGVV--------VIDNTSHFRYDYDIPLVVPEVNP 115
Query: 119 DHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGAGFS 177
+ + E + + I+ NPNCST + ++L P+ + GI+++ V T Q++SGAG +
Sbjct: 116 E--AIAEFRNRN------IIANPNCSTIQMLVALKPIYDAVGIERINVTTYQSVSGAGKA 167
Query: 178 GLSAYA--------------------IQDNVIPFI--------SGEEWKIENESKKIMGK 209
G+ A I N IP I + EE K+ E++KI
Sbjct: 168 GIDELAGQTAKLLNGYPAETQAFSQQIAFNCIPQIDQFMDNGYTKEEMKMVWETQKI--- 224
Query: 210 LKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP-DIKSIREAIENFDPLKDLKLPS 268
S V RVPV +GH EAV VE P D + + + +E D ++
Sbjct: 225 -----FNDPSIMVNPTCVRVPVFYGHAEAVHVETRAPIDAEQVMDMLEQTDGIE------ 273
Query: 269 YEKPIVYTEIPQPRLHRDRGRGLTVTVGRLERT---SEGVKYVALGHNLVRGAAGGSVLN 325
++ P RD G V VGR+ G+ + N+ +GAA +V
Sbjct: 274 -----LFRGADFPTQVRDAGGKDHVLVGRVRNDISHHSGINLWVVADNVRKGAATNAVQI 328
Query: 326 AEL 328
AEL
Sbjct: 329 AEL 331
>sp|P23247|DHAS_VIBCH ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA DEHYDROGENASE) (ASADH)
Length = 337
Score = 102 bits (253), Expect = 4e-21
Identities = 107/363 (29%), Positives = 160/363 (43%), Gaps = 76/363 (20%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKL--IASEKSAGKKY---GDLVEDSPEEFRDYY 58
VA+ GATG VG T +++L F V++L +ASE+S GK Y G V E D+
Sbjct: 7 VAIFGATGAVGETMLEVLQERE-FPVDELFLLASERSEGKTYRFNGKTVRVQNVEEFDWS 65
Query: 59 VISLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNK 118
+ + F + G +L P + V V N RYD D+P++VPEVN
Sbjct: 66 QVHIALF--SAGGELSAKWAPIAAEAGVV--------VIDNTSHFRYDYDIPLVVPEVNP 115
Query: 119 DHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGAGFS 177
+ + E + + I+ NPNCST + ++L P+ + GI+++ V T Q++SGAG +
Sbjct: 116 E--AIAEFRNRN------IIANPNCSTIQMLVALKPIYDAVGIERINVTTYQSVSGAGKA 167
Query: 178 GLSAYA--------------------IQDNVIPFI--------SGEEWKIENESKKIMGK 209
G+ A I N IP I + EE K+ E++KI
Sbjct: 168 GIDELAGQTAKLLNGYPAETNTFSQQIAFNCIPQIDQFMDNGYTKEEMKMVWETQKI--- 224
Query: 210 LKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP-DIKSIREAIENFDPLKDLKLPS 268
S V RVPV +GH EAV VE P D + + + +E D ++
Sbjct: 225 -----FNDPSIMVNPTCVRVPVFYGHAEAVHVETRAPIDAEQVMDMLEQTDGIE------ 273
Query: 269 YEKPIVYTEIPQPRLHRDRGRGLTVTVGRLERT---SEGVKYVALGHNLVRGAAGGSVLN 325
++ P RD G V VGR+ G+ + N+ +GAA +V
Sbjct: 274 -----LFRGADFPTQVRDAGGKDHVLVGRVRNDISHHSGINLWVVADNVRKGAATNAVQI 328
Query: 326 AEL 328
AEL
Sbjct: 329 AEL 331
>pir||B82118 probable aspartate-semialdehyde dehydrogenase VC2107 [imported] -
Vibrio cholerae (group O1 strain N16961)
>gi|9656657|gb|AAF95253.1| (AE004284)
aspartate-semialdehyde dehydrogenase, putative [Vibrio
cholerae]
Length = 338
Score = 102 bits (253), Expect = 4e-21
Identities = 107/363 (29%), Positives = 160/363 (43%), Gaps = 76/363 (20%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKL--IASEKSAGKKY---GDLVEDSPEEFRDYY 58
VA+ GATG VG T +++L F V++L +ASE+S GK Y G V E D+
Sbjct: 8 VAIFGATGAVGETMLEVLQERE-FPVDELFLLASERSEGKTYRFNGKTVRVQNVEEFDWS 66
Query: 59 VISLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNK 118
+ + F + G +L P + V V N RYD D+P++VPEVN
Sbjct: 67 QVHIALF--SAGGELSAKWAPIAAEAGVV--------VIDNTSHFRYDYDIPLVVPEVNP 116
Query: 119 DHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGAGFS 177
+ + E + + I+ NPNCST + ++L P+ + GI+++ V T Q++SGAG +
Sbjct: 117 E--AIAEFRNRN------IIANPNCSTIQMLVALKPIYDAVGIERINVTTYQSVSGAGKA 168
Query: 178 GLSAYA--------------------IQDNVIPFI--------SGEEWKIENESKKIMGK 209
G+ A I N IP I + EE K+ E++KI
Sbjct: 169 GIDELAGQTAKLLNGYPAETNTFSQQIAFNCIPQIDQFMDNGYTKEEMKMVWETQKI--- 225
Query: 210 LKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP-DIKSIREAIENFDPLKDLKLPS 268
S V RVPV +GH EAV VE P D + + + +E D ++
Sbjct: 226 -----FNDPSIMVNPTCVRVPVFYGHAEAVHVETRAPIDAEQVMDMLEQTDGIE------ 274
Query: 269 YEKPIVYTEIPQPRLHRDRGRGLTVTVGRLERT---SEGVKYVALGHNLVRGAAGGSVLN 325
++ P RD G V VGR+ G+ + N+ +GAA +V
Sbjct: 275 -----LFRGADFPTQVRDAGGKDHVLVGRVRNDISHHSGINLWVVADNVRKGAATNAVQI 329
Query: 326 AEL 328
AEL
Sbjct: 330 AEL 332
>emb|CAA66607.1| (X97964) aspartate-semialdehyde dehydrogenase [Campylobacter
jejuni]
Length = 343
Score = 102 bits (252), Expect = 6e-21
Identities = 97/311 (31%), Positives = 150/311 (48%), Gaps = 73/311 (23%)
Query: 2 KRVAVLGATGLVGRTFVKLLGGHPWFKVEKLI--ASEKSAGKKYGDLVEDSPEEFR--DY 57
+++A++GATG VG + +L F VE ++ AS KSAG + EFR Y
Sbjct: 5 QKIAIVGATGAVGEELLNVLDELD-FPVESILPLASAKSAGNQI---------EFRGKSY 54
Query: 58 YVISLNE--FLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAH-RYDEDVPILVP 114
+ L E F ENP VD+ F + S+S + + V + +H R +EDVP++VP
Sbjct: 55 TIKELTEDAFRENP-VDIAFFSAGGSVSEKYAKFAVEAGAVVIDNTSHFRMEEDVPLVVP 113
Query: 115 EVNKDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISG 173
E N + +K + K+ G I+ NPNCST + L PL + F +K+V V+T QA SG
Sbjct: 114 ECNPEDIK----EWKKTG----IIANPNCSTIQMVHILKPLNDAFDLKRVDVSTYQAASG 165
Query: 174 AGFSGLS----------AYAIQD------------NVIPFI--------SGEEWKIENES 203
AG G+ A+ + + N+IP I + EE K+ NE+
Sbjct: 166 AGKEGMEELVRAMQSFFAFKLDEFEAQTFPHTLALNLIPQIDVFMDNGYTKEELKMINET 225
Query: 204 KKIMGKLKGDEIEPASFDVIAIATRVPVIHGHTEAVFVEL-ENPDIKSIREAIEN----- 257
+KI+ K + ++ A RVPV+ H+EA+ + + D+ R+ ++N
Sbjct: 226 QKILHK---------NLEISATCVRVPVLRSHSEAITMHFAKEVDVNKARDILQNAPSVV 276
Query: 258 -FDPLKDLKLP 267
D KD K P
Sbjct: 277 VIDEPKDKKYP 287
>sp|O31219|DHAS_LEGPN ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA DEHYDROGENASE) (ASADH)
>gi|2645882|gb|AAC46292.1| (AF034213)
aspartate-B-semialdehyde dehydrogenase [Legionella
pneumophila]
Length = 347
Score = 102 bits (252), Expect = 6e-21
Identities = 111/370 (30%), Positives = 167/370 (45%), Gaps = 87/370 (23%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKL--IASEKSAGKKYGDLVEDSPEEFRDYY--V 59
VA++GATG VG TF+ +L F ++ L +AS +S GK FRD V
Sbjct: 7 VAIVGATGAVGETFLTVLEERN-FPIKSLYPLASSRSVGKTV---------TFRDQELDV 56
Query: 60 ISLNEFLENPGVDLVFNALPASISRDVEEK-LAQEIPVFTNARAHRYDEDVPILVP---- 114
+ L EF + VDL + ++S++ K +A V N RY++D+P++VP
Sbjct: 57 LDLAEF-DFSKVDLALFSAGGAVSKEYAPKAVAAGCVVVDNTSCFRYEDDIPLVVPGSES 115
Query: 115 EVNKDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISG 173
N+D+ K RG I+ NPNCST + ++L P+ + GI ++ VAT Q++SG
Sbjct: 116 SSNRDYTK--------RG----IIANPNCSTIQMVVALKPIYDAVGISRINVATYQSVSG 163
Query: 174 AGFSGLSAYAIQD--------------------NVIPFI--------SGEEWKIENESKK 205
G +S Q N +P I + EE K+ E++K
Sbjct: 164 TGKKAISELVAQVGDLLNGRPANVQVYPQQIAFNALPHIDQFEDNGYTREEMKMVWETRK 223
Query: 206 IMGKLKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP----DIKSIREAIENFDPL 261
IM E S V A RVPVI+GH+EAV +EL+ P D +++ +
Sbjct: 224 IM--------EDDSIMVNPTAVRVPVIYGHSEAVHLELKKPLTADDARALLAKAPGVTVV 275
Query: 262 KDLKLPSYEKPIVYTEIPQPRLHRDRGRGLTVTVGRLERTSE---GVKYVALGHNLVRGA 318
+L SY T I H D V VGR+ + G+ + N+ +GA
Sbjct: 276 DNLSKASYP-----TAIKNAVGHDD------VFVGRIRQDISHPCGLNLWIVADNIRKGA 324
Query: 319 AGGSVLNAEL 328
A +V AE+
Sbjct: 325 ATNAVQIAEI 334
>sp|Q59291|DHAS_CAMJE ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA DEHYDROGENASE) (ASADH)
>gi|11251963|pir||D81304 aspartate-semialdehyde
dehydrogenase (EC 1.2.1.11) Cj1023c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968459|emb|CAB73279.1| (AL139077)
aspartate-semialdehyde dehydrogenase [Campylobacter
jejuni]
Length = 343
Score = 102 bits (251), Expect = 8e-21
Identities = 94/324 (29%), Positives = 155/324 (47%), Gaps = 62/324 (19%)
Query: 2 KRVAVLGATGLVGRTFVKLLGGHPWFKVEKLI--ASEKSAGKKYGDLVEDSPEEFRDYYV 59
+++A++GATG VG + +L F VE ++ AS KS G + VE + ++
Sbjct: 5 QKIAIVGATGAVGEELLNVLDELD-FPVESILPLASAKSVGSE----VEFKGKAYK-VKE 58
Query: 60 ISLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAH-RYDEDVPILVPEVNK 118
++ N F ENP +D+ F + S+S + + V + +H R ++DVP++VPE N
Sbjct: 59 LTENVFKENP-IDIAFFSAGGSVSEKYAKFAVESGAVVIDNTSHFRMEKDVPLVVPECNP 117
Query: 119 DHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGAGFS 177
+ +K K+ G I+ NPNCST + L PL + F +K+V V+T QA SGAG
Sbjct: 118 EDIK----DWKKTG----IIANPNCSTIQMVQVLKPLNDAFNLKRVDVSTYQAASGAGKE 169
Query: 178 GLS----------------------AYAIQDNVIPFI--------SGEEWKIENESKKIM 207
G+ Y + N+IP I + EE K+ NE++KI+
Sbjct: 170 GMQELVEAMQSFFAFKLDEFEPQTFPYTLALNLIPQIDVFMDNDYTKEELKMVNETQKIL 229
Query: 208 GKLKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP-DIKSIREAIENFDP---LKD 263
K + +V A RVPV+ H+EA+ + E D+K +E ++ + D
Sbjct: 230 HK---------NLEVSATCVRVPVLRSHSEAITMHFEKEIDVKKAKEILKKAPSVIVIDD 280
Query: 264 LKLPSYEKPIVYTEIPQPRLHRDR 287
K Y P++ ++ + + R R
Sbjct: 281 PKNKKYPMPLMTSDTNETYVGRIR 304
>emb|CAA75569.1| (Y15281) aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
Length = 337
Score = 101 bits (250), Expect = 1e-20
Identities = 106/363 (29%), Positives = 160/363 (43%), Gaps = 76/363 (20%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKL--IASEKSAGKKY---GDLVEDSPEEFRDYY 58
VA+ GATG VG T +++L F V++L +AS++S GK Y G V E D+
Sbjct: 7 VAIFGATGAVGETMLEVLQERE-FPVDELFLLASDRSEGKTYRFNGKTVRVQNVEEFDWS 65
Query: 59 VISLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNK 118
+ + F + G +L P + V V N RYD D+P++VPEVN
Sbjct: 66 QVHIALF--SAGGELSAKWAPIAAEAGVV--------VIDNTSHFRYDYDIPLVVPEVNP 115
Query: 119 DHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGAGFS 177
+ + E + + I+ NPNCST + ++L P+ + GI+++ V T Q++SGAG +
Sbjct: 116 E--AIAEFRNRN------IIANPNCSTIQMLVALKPIYDAVGIERINVTTYQSVSGAGKA 167
Query: 178 GLSAYA--------------------IQDNVIPFI--------SGEEWKIENESKKIMGK 209
G+ A I N IP I + EE K+ E++KI
Sbjct: 168 GIDELAGQTAKLLNGYPAETNTFSQQIAFNCIPQIDQFMDNGYTKEEMKMVWETQKI--- 224
Query: 210 LKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP-DIKSIREAIENFDPLKDLKLPS 268
S V RVPV +GH EAV VE P D + + + +E D ++
Sbjct: 225 -----FNDPSIMVNPTCVRVPVFYGHAEAVHVETRAPIDAEQVMDMLEQTDGIE------ 273
Query: 269 YEKPIVYTEIPQPRLHRDRGRGLTVTVGRLERT---SEGVKYVALGHNLVRGAAGGSVLN 325
++ P RD G V VGR+ G+ + N+ +GAA +V
Sbjct: 274 -----LFRGADFPTQVRDAGGKDHVLVGRVRNDISHHSGINLWVVADNVRKGAATNAVQI 328
Query: 326 AEL 328
AEL
Sbjct: 329 AEL 331
>gb|AAG33078.1|AF207064_1 (AF207064) aspartate-semialdehyde dehydrogenase precursor
[Arabidopsis thaliana]
Length = 340
Score = 97.5 bits (239), Expect = 2e-19
Identities = 98/365 (26%), Positives = 164/365 (44%), Gaps = 72/365 (19%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPW-FKVEKLIASEKSAGKKYGDLVEDSPEEFRDYYVISL 62
+AV+G TG VG+ F+ +L + + K++AS++SAGK+ + +Y V L
Sbjct: 6 LAVVGVTGAVGQEFLSVLSDRDFPYSSIKMLASKRSAGKRVAF-------DGHEYTVEEL 58
Query: 63 NEFLENPGVDLVFNALPASISRDVEEKLAQE-IPVFTNARAHRYDEDVPILVPEVNKDHL 121
N GVD+ + SIS++ A++ V N+ A R + VP+++PEVN + +
Sbjct: 59 TADSFN-GVDIALFSAGGSISKEFGPLAAEKGTIVVDNSSAFRMVDGVPLVIPEVNPEAM 117
Query: 122 KLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRNFG-IKKVRVATMQAISGAGFSGLS 180
K ++V KG ++ NPNCST I +++ PL + +K++ V+T QA SGAG + +
Sbjct: 118 KGIKVGMG----KGALIANPNCSTIICLMAVTPLHHHAKVKRMVVSTYQAASGAGAAAME 173
Query: 181 ------------------------AYAIQDNVIPFISG----EEWKIENESKKIMGKLKG 212
A+ + + P + EE K+ E++KI
Sbjct: 174 ELVQQTREVLEGKPPTCNIFGQQYAFNLFSHNAPILDNGYNEEEMKLVKETRKIW----- 228
Query: 213 DEIEPASFDVIAIATRVPVIHGHTEAVFVELENP-DIKSIREAIENFDP---LKDLKLPS 268
V A RVPV+ H E+V ++ ENP D + RE ++ + D +
Sbjct: 229 ---NDTEVKVTATCIRVPVMRAHAESVNLQFENPLDENTAREILKKAPGVYIIDDRASNT 285
Query: 269 YEKPIVYTEIPQPRLHRDRGRGLTVTVGRLERT-----SEGVKYVALGHNLVRGAAGGSV 323
+ P+ D V VGR+ R + G+ G + +GAA +V
Sbjct: 286 FPTPL------------DVSNKDDVAVGRIRRDVSQDGNFGLDIFVCGDQIRKGAALNAV 333
Query: 324 LNAEL 328
AE+
Sbjct: 334 QIAEM 338
>sp|Q56734|DHAS_SHEVI ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA DEHYDROGENASE) (ASADH)
>gi|7431496|pir||JC5436 aspartate-semialdehyde
dehydrogenase (EC 1.2.1.11) - Shewanella sp. DSS12
>gi|747692|dbj|BAA08490.1| (D49540) aspartate
beta-D-semialdehyde dehydrogenese [Shewanella violacea]
Length = 338
Score = 96.7 bits (237), Expect = 3e-19
Identities = 113/372 (30%), Positives = 165/372 (43%), Gaps = 93/372 (25%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKL--IASEKSAGKKY---GDLVEDSPEEFRDYY 58
V VLGA+G VG+T +++L F V KL +AS +SAG G VE + D+
Sbjct: 7 VVVLGASGAVGQTMIEILEERN-FPVAKLFPLASSRSAGGTVSFNGKQVEILDVDDFDWS 65
Query: 59 VISLNEFLENPGVDLVFNALPASISRDVEEKLA-----QEIPVFTNARAHRYDEDVPILV 113
+ F S DV EK A V N RYD DVP+++
Sbjct: 66 QAQIGFF---------------SAGGDVSEKWAPIAAENGCVVIDNTSQFRYDNDVPLVI 110
Query: 114 PEVNKDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAIS 172
PEVN + + + + + I+ NPNCST + ++L P+ + FGI ++ VAT Q++S
Sbjct: 111 PEVNPE--AIADFRNRN------IIANPNCSTIQMLVALKPIYDAFGISRINVATYQSVS 162
Query: 173 GAGFSGLSAYA--------------------IQDNVIPFI--------SGEEWKIENESK 204
G+G ++ A I NV+P I + EE K+ E++
Sbjct: 163 GSGKEAITELAGQCSKLLHGLPAESKVYPKQIAFNVLPQIDKFMENGYTKEEMKMVWETQ 222
Query: 205 KIMGKLKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP----DIKSI-REAIENFD 259
KI G D I V A RVPV +GH+EA+ +E P D+K++ REA
Sbjct: 223 KIFG---DDNIV-----VNPTAVRVPVFYGHSEAIHLETIQPAEAEDVKAVLREA----- 269
Query: 260 PLKDLKLPSYEKPIVYTEIPQPRLHRDRGRGLTVTVGRLERT---SEGVKYVALGHNLVR 316
P +L + E P TE V VGR+ + S G+ + N+ +
Sbjct: 270 PGIELFESNEEYPTAVTESAGTD---------PVYVGRVRKDISHSHGINLWVVSDNIRK 320
Query: 317 GAAGGSVLNAEL 328
GAA SV AE+
Sbjct: 321 GAALNSVQIAEV 332
>gb|AAC43359.1| (U25070) aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
Length = 316
Score = 96.0 bits (235), Expect = 6e-19
Identities = 90/294 (30%), Positives = 136/294 (45%), Gaps = 62/294 (21%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKL--IASEKSAGKKY---GDLVEDSPEEFRDYY 58
VA+ GATG VG T +++L F V++L +ASE+S GK Y G V E D+
Sbjct: 7 VAIFGATGAVGETMLEVLQERE-FPVDELFLLASERSEGKTYRFNGKTVRVQNVEEFDWS 65
Query: 59 VISLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNK 118
+ + F + G +L P + V V N RYD D+P++VPEVN
Sbjct: 66 QVHIALF--SAGGELSAKWAPIAAEAGVV--------VIDNTSHFRYDYDIPLVVPEVNP 115
Query: 119 DHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGAGFS 177
+ + E + + I+ NPNCST + ++L P+ + GI+++ V T Q++SGAG +
Sbjct: 116 E--AIAEFRNRN------IIANPNCSTIQMLVALKPIYDAVGIERINVTTYQSVSGAGKA 167
Query: 178 GLSAYA--------------------IQDNVIPFI--------SGEEWKIENESKKIMGK 209
G+ A I N IP I + EE K+ E++KI
Sbjct: 168 GIDELAGQTAKLLNGYPAETNTFSQQIAFNCIPQIDQFMDNGYTKEEMKMVWETQKI--- 224
Query: 210 LKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP-DIKSIREAIENFDPLK 262
S V + RVPV +GH EAV VE P D + + + +E D ++
Sbjct: 225 -----FNDPSIMVNPMCVRVPVFYGHAEAVHVETRAPIDAEQVMDMLEQTDGIE 273
>gb|AAC43361.1| (U25072) aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
Length = 316
Score = 95.6 bits (234), Expect = 7e-19
Identities = 89/294 (30%), Positives = 138/294 (46%), Gaps = 62/294 (21%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKL--IASEKSAGKKY---GDLVEDSPEEFRDYY 58
VA+ GATG VG T +++L F V++L +ASE+S GK Y G V E D+
Sbjct: 7 VAIFGATGAVGETMLEVLQERE-FPVDELFLLASERSEGKTYRFNGKTVRVQNVEEFDWS 65
Query: 59 VISLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNK 118
+ + F + G +L + P + V V N RYD D+P+++PEVN
Sbjct: 66 QVHIALF--SAGGELSAHWAPIAAEAGVV--------VIDNTSHFRYDYDIPLVIPEVNP 115
Query: 119 DHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGAGFS 177
+ + E + + I+ NPNCST + ++L P+ + GI+++ V T Q++SGAG +
Sbjct: 116 E--AIAEFRNRN------IIANPNCSTIQMLVALKPIYDAVGIERINVTTYQSVSGAGKA 167
Query: 178 G-----------LSAYAIQDNV---------IPFI--------SGEEWKIENESKKIMGK 209
G L+ Y ++ N IP I + EE K+ E++KI
Sbjct: 168 GIDELAGQTAKLLNGYPVETNTFSQQIAFNCIPQIDQFMDNGYTKEEMKMVWETQKI--- 224
Query: 210 LKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP-DIKSIREAIENFDPLK 262
S V RVPV +GH EAV VE P D + + + +E D ++
Sbjct: 225 -----FNDPSIMVNPTCVRVPVFYGHAEAVHVETRAPIDAEQVMDMLEQTDGIE 273
>gb|AAC43355.1| (U25065) aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
>gi|882349|gb|AAC43357.1| (U25068)
aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
>gi|882355|gb|AAC43360.1| (U25071)
aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
>gi|882363|gb|AAC43364.1| (U25075)
aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
>gi|882375|gb|AAC43370.1| (U25081)
aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
>gi|882381|gb|AAC43373.1| (U25084)
aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
>gi|882385|gb|AAC43375.1| (U25086)
aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
>gi|882387|gb|AAC43376.1| (U25087)
aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
Length = 316
Score = 95.2 bits (233), Expect = 1e-18
Identities = 90/294 (30%), Positives = 135/294 (45%), Gaps = 62/294 (21%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKL--IASEKSAGKKY---GDLVEDSPEEFRDYY 58
VA+ GATG VG T +++L F V++L +ASE+S GK Y G V E D+
Sbjct: 7 VAIFGATGAVGETMLEVLQERE-FPVDELFLLASERSEGKTYRFNGKTVRVQNVEEFDWS 65
Query: 59 VISLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNK 118
+ + F + G +L P + V V N RYD D+P++VPEVN
Sbjct: 66 QVHIALF--SAGGELSAKWAPIAAEAGVV--------VIDNTSHFRYDYDIPLVVPEVNP 115
Query: 119 DHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGAGFS 177
+ + E + + I+ NPNCST + ++L P+ + GI+++ V T Q++SGAG +
Sbjct: 116 E--AIAEFRNRN------IIANPNCSTIQMLVALKPIYDAVGIERINVTTYQSVSGAGKA 167
Query: 178 GLSAYA--------------------IQDNVIPFI--------SGEEWKIENESKKIMGK 209
G+ A I N IP I + EE K+ E++KI
Sbjct: 168 GIDELAGQTAKLLNGYPAETNTFSQQIAFNCIPQIDQFMDNGYTKEEMKMVWETQKI--- 224
Query: 210 LKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP-DIKSIREAIENFDPLK 262
S V RVPV +GH EAV VE P D + + + +E D ++
Sbjct: 225 -----FNDPSIMVNPTCVRVPVFYGHAEAVHVETRAPIDAEQVMDMLEQTDGIE 273
>gb|AAC43356.1| (U25066) aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
>gi|882359|gb|AAC43362.1| (U25073)
aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
>gi|882367|gb|AAC43366.1| (U25077)
aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
>gi|882383|gb|AAC43374.1| (U25085)
aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
Length = 316
Score = 95.2 bits (233), Expect = 1e-18
Identities = 90/294 (30%), Positives = 135/294 (45%), Gaps = 62/294 (21%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKL--IASEKSAGKKY---GDLVEDSPEEFRDYY 58
VA+ GATG VG T +++L F V++L +ASE+S GK Y G V E D+
Sbjct: 7 VAIFGATGAVGETMLEVLQERE-FPVDELFLLASERSEGKTYRFNGKTVRVQNVEEFDWS 65
Query: 59 VISLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNK 118
+ + F + G +L P + V V N RYD D+P++VPEVN
Sbjct: 66 QVHIALF--SAGGELSAKWAPIAAEAGVV--------VIDNTSHFRYDYDIPLVVPEVNP 115
Query: 119 DHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGAGFS 177
+ + E + + I+ NPNCST + ++L P+ + GI+++ V T Q++SGAG +
Sbjct: 116 E--AIAEFRNRN------IIANPNCSTIQMLVALKPIYDAVGIERINVTTYQSVSGAGKA 167
Query: 178 GLSAYA--------------------IQDNVIPFI--------SGEEWKIENESKKIMGK 209
G+ A I N IP I + EE K+ E++KI
Sbjct: 168 GIDELAGQTAKLLNGYPAETQAFSQQIAFNCIPQIDQFMDNGYTKEEMKMVWETQKI--- 224
Query: 210 LKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP-DIKSIREAIENFDPLK 262
S V RVPV +GH EAV VE P D + + + +E D ++
Sbjct: 225 -----FNDPSIMVNPTCVRVPVFYGHAEAVHVETRAPIDAEQVMDMLEQTDGIE 273
>gb|AAC43358.1| (U25069) aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
Length = 316
Score = 95.2 bits (233), Expect = 1e-18
Identities = 90/294 (30%), Positives = 135/294 (45%), Gaps = 62/294 (21%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKL--IASEKSAGKKY---GDLVEDSPEEFRDYY 58
VA+ GATG VG T +++L F V++L +ASE+S GK Y G V E D+
Sbjct: 7 VAIFGATGAVGETMLEVLQERE-FPVDELFLLASERSEGKTYRFKGKTVRVQNVEEFDWS 65
Query: 59 VISLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNK 118
+ + F + G +L P + V V N RYD D+P++VPEVN
Sbjct: 66 QVHIALF--SAGGELSAKWAPIAAEAGVV--------VIDNTSHFRYDYDIPLVVPEVNP 115
Query: 119 DHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGAGFS 177
+ + E + + I+ NPNCST + ++L P+ + GI+++ V T Q++SGAG +
Sbjct: 116 E--AIAEFRNRN------IIANPNCSTIQMLVALKPIYDAVGIERINVTTYQSVSGAGKA 167
Query: 178 GLSAYA--------------------IQDNVIPFI--------SGEEWKIENESKKIMGK 209
G+ A I N IP I + EE K+ E++KI
Sbjct: 168 GIDELAGQTAKLLNGYPAETNTFSQQIAFNCIPQIDQFMDNGYTKEEMKMVWETQKI--- 224
Query: 210 LKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP-DIKSIREAIENFDPLK 262
S V RVPV +GH EAV VE P D + + + +E D ++
Sbjct: 225 -----FNDPSIMVNPTCVRVPVFYGHAEAVHVETRAPIDAEQVMDMLEQTDGIE 273
>gb|AAC43363.1| (U25074) aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
Length = 316
Score = 95.2 bits (233), Expect = 1e-18
Identities = 90/294 (30%), Positives = 135/294 (45%), Gaps = 62/294 (21%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKL--IASEKSAGKKY---GDLVEDSPEEFRDYY 58
VA+ GATG VG T +++L F V++L +ASE+S GK Y G V E D+
Sbjct: 7 VAIFGATGAVGETMLEVLQERE-FPVDELFLLASERSEGKTYRFNGKTVRVQNVEEFDWS 65
Query: 59 VISLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNK 118
+ + F + G +L P + V V N RYD D+P++VPEVN
Sbjct: 66 QVHIALF--SAGGELSAKWAPIAAEAGVV--------VIDNTSHFRYDYDIPLVVPEVNP 115
Query: 119 DHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGAGFS 177
+ + E + + I+ NPNCST + ++L P+ + GI+++ V T Q++SGAG +
Sbjct: 116 E--AIAEFRNRN------IIANPNCSTIQMLVALKPIYDAVGIERINVTTYQSVSGAGKA 167
Query: 178 GLSAYA--------------------IQDNVIPFI--------SGEEWKIENESKKIMGK 209
G+ A I N IP I + EE K+ E++KI
Sbjct: 168 GIDELAGQTDKLLNGYPAETQAFSQQIAFNCIPQIDQFMDNGYTKEEMKMVWETQKI--- 224
Query: 210 LKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP-DIKSIREAIENFDPLK 262
S V RVPV +GH EAV VE P D + + + +E D ++
Sbjct: 225 -----FNDPSIMVNPTCVRVPVFYGHAEAVHVETRAPIDAEQVMDMLEQTDGIE 273
>gb|AAC43365.1| (U25076) aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
Length = 316
Score = 95.2 bits (233), Expect = 1e-18
Identities = 88/294 (29%), Positives = 133/294 (44%), Gaps = 62/294 (21%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKL--IASEKSAGKKY---GDLVEDSPEEFRDYY 58
VA+ GATG VG T +++L F V++L +ASE+S GK Y G V E D+
Sbjct: 7 VAIFGATGAVGETMLEVLQERE-FPVDELFLLASERSEGKTYRFNGKTVRVQNVEEFDWS 65
Query: 59 VISLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNK 118
+ + F + + L A + V N RYD D+P++VPEVN
Sbjct: 66 QVHIALFSAGGELSAKWAPLAAEAG----------VVVIDNTSHFRYDYDIPLVVPEVNP 115
Query: 119 DHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGAGFS 177
+ + E + + I+ NPNCST + ++L P+ + GI+++ V T Q++SGAG +
Sbjct: 116 E--AIAEFRNRN------IIANPNCSTIQMLVALKPIYDAVGIERINVTTYQSVSGAGKA 167
Query: 178 GLSAYA--------------------IQDNVIPFI--------SGEEWKIENESKKIMGK 209
G+ A I N IP I + EE K+ E++KI
Sbjct: 168 GIDELAGQTAKLLNGYPAETQAFSQQIAFNCIPQIDQFMDNGYTKEEMKMVWETQKI--- 224
Query: 210 LKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP-DIKSIREAIENFDPLK 262
S V RVPV +GH EAV VE P D + + + +E D ++
Sbjct: 225 -----FNDPSIMVNPTCVRVPVFYGHAEAVHVETRAPIDAEQVMDMLEQTDGIE 273
>gb|AAC43371.1| (U25082) aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
>gi|882379|gb|AAC43372.1| (U25083)
aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
Length = 316
Score = 95.2 bits (233), Expect = 1e-18
Identities = 88/294 (29%), Positives = 133/294 (44%), Gaps = 62/294 (21%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKL--IASEKSAGKKY---GDLVEDSPEEFRDYY 58
VA+ GATG VG T +++L F V++L +ASE+S GK Y G V E D+
Sbjct: 7 VAIFGATGAVGETMLEVLQERE-FPVDELFLLASERSEGKTYRFNGKTVRVQNVEEFDWS 65
Query: 59 VISLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNK 118
+ + F + + L A + V N RYD D+P++VPEVN
Sbjct: 66 QVHIALFSAGGELSAKWAPLAAEAG----------VVVIDNTSHFRYDYDIPLVVPEVNP 115
Query: 119 DHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGAGFS 177
+ + E + + I+ NPNCST + ++L P+ + GI+++ V T Q++SGAG +
Sbjct: 116 E--AIAEFRNRN------IIANPNCSTIQMLVALKPIYDAVGIERINVTTYQSVSGAGKA 167
Query: 178 GLSAYA--------------------IQDNVIPFI--------SGEEWKIENESKKIMGK 209
G+ A I N IP I + EE K+ E++KI
Sbjct: 168 GIDELAGQTAKLLNGYPAETNTFSQQIAFNCIPQIDQFMDNGYTKEEMKMVWETQKI--- 224
Query: 210 LKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP-DIKSIREAIENFDPLK 262
S V RVPV +GH EAV VE P D + + + +E D ++
Sbjct: 225 -----FNDPSIMVNPTCVRVPVFYGHAEAVHVETRAPIDAEQVMDMLEQTDGIE 273
>sp|Q56732|DHAS_SHESP ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA DEHYDROGENASE) (ASADH)
>gi|7431497|pir||JC5435 aspartate-semialdehyde
dehydrogenase (EC 1.2.1.11) - Shewanella sp. DB6705
>gi|747689|dbj|BAA08488.1| (D49539) aspartate
beta-D-semialdehyde dehydrogenese [Shewanella sp.]
Length = 338
Score = 94.4 bits (231), Expect = 2e-18
Identities = 108/367 (29%), Positives = 159/367 (42%), Gaps = 83/367 (22%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKL--IASEKSAGKKY---GDLVEDSPEEFRDYY 58
V VLGA+G VG+T +++L F + KL +AS +SAG G VE + D+
Sbjct: 7 VVVLGASGAVGQTIIEILQERN-FPIAKLFPLASSRSAGGTVSFNGKQVEILDVDDFDWS 65
Query: 59 VISLNEFLENPGVDLVFNALPASISRDVEEKLA-----QEIPVFTNARAHRYDEDVPILV 113
+ F S DV EK A V N RYD DVP+++
Sbjct: 66 QAQIGFF---------------SAGGDVSEKWAPIAAESGCVVIDNTSHFRYDNDVPLVI 110
Query: 114 PEVNKDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAIS 172
PEVN + + + + + I+ NPNCST + ++L P+ + FGI ++ VAT Q++S
Sbjct: 111 PEVNPE--AIADFRNRN------IIANPNCSTIQMLVALKPIYDAFGISRINVATYQSVS 162
Query: 173 GAGFSGLSAYA--------------------IQDNVIPFI--------SGEEWKIENESK 204
G+G ++ A I NV+P I + EE K+ E++
Sbjct: 163 GSGKEAIAELAGQCSKLLQGLPIEPKVYSKQIAFNVLPQIDTFMENGYTKEEMKMVWETQ 222
Query: 205 KIMGKLKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENPDIKSIREAIENFDPLKDL 264
KI G D I V A RVPV GH+EA+ +E P +A+ P +L
Sbjct: 223 KIFG---DDNIV-----VNPTAVRVPVFFGHSEAIHLETIQPAEAEDVKAVLRDAPGIEL 274
Query: 265 KLPSYEKPIVYTEIPQPRLHRDRGRGLTVTVGRLERT---SEGVKYVALGHNLVRGAAGG 321
+ E P TE V VGR+ + S G+ + N+ +GAA
Sbjct: 275 FESNEEYPTAVTESAGTD---------PVYVGRVRKDISHSHGINLWVVSDNIRKGAALN 325
Query: 322 SVLNAEL 328
SV AE+
Sbjct: 326 SVQIAEV 332
>gb|AAC43368.1| (U25079) aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
>gi|882373|gb|AAC43369.1| (U25080)
aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
Length = 316
Score = 93.6 bits (229), Expect = 3e-18
Identities = 88/294 (29%), Positives = 135/294 (44%), Gaps = 62/294 (21%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKL--IASEKSAGKKY---GDLVEDSPEEFRDYY 58
VA+ GATG VG T +++L F V++L +ASE+S GK Y G V E D+
Sbjct: 7 VAIFGATGAVGETMLEVLQERE-FPVDELFLLASERSEGKTYRFNGKTVRVQNVEEFDWS 65
Query: 59 VISLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNK 118
+ + F + G +L P + V V N RYD D+P+++PEVN
Sbjct: 66 QVHIALF--SAGGELSAKWAPIAAEAGVV--------VIDNTSHFRYDYDIPLVIPEVNP 115
Query: 119 DHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGAGFS 177
+ + E + + I+ NPNCST + ++L P+ + GI+++ V T Q++SGAG +
Sbjct: 116 E--AIAEFRNRN------IIANPNCSTIQMLVALKPIYDAVGIERINVTTYQSVSGAGKA 167
Query: 178 GLSAYA--------------------IQDNVIPFI--------SGEEWKIENESKKIMGK 209
G+ A I N IP I + EE K+ E++KI
Sbjct: 168 GIDELAGQTAKLLNGYPAETNTFSQQIAFNCIPQIDQFMDNGYTKEEMKMVWETQKI--- 224
Query: 210 LKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP-DIKSIREAIENFDPLK 262
S V RVPV +GH EAV VE P D + + + ++ D ++
Sbjct: 225 -----FNDPSIMVNPTCVRVPVFYGHAEAVHVETRAPIDAEQVMDMLDQTDGIE 273
>sp|Q60080|DHAS_VIBMI ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA DEHYDROGENASE) (ASADH)
>gi|882389|gb|AAC43377.1| (U25067)
aspartate-semialdehyde dehydrogenase [Vibrio mimicus]
Length = 316
Score = 93.2 bits (228), Expect = 4e-18
Identities = 88/294 (29%), Positives = 135/294 (44%), Gaps = 62/294 (21%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKL--IASEKSAGKKY---GDLVEDSPEEFRDYY 58
VA+ GATG VG T +++L F V++L +ASE+S GK Y G V E D+
Sbjct: 7 VAIFGATGAVGETMLEVLQERE-FPVDELFLLASERSEGKTYRFNGKTVRVQNVEEFDWS 65
Query: 59 VISLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNK 118
+ + F + G +L + P V V N RYD D+P+++PEVN
Sbjct: 66 QVHIALF--SAGGELSAHWAPIRAEAGVV--------VIDNTSHFRYDYDIPLVIPEVNP 115
Query: 119 DHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGAGFS 177
+ + E + + I+ NPNCST + ++L P+ + GI+++ V T Q++SGAG +
Sbjct: 116 E--AIAEFRNRN------IIANPNCSTIQMLVALKPIYDAVGIERINVTTYQSVSGAGKA 167
Query: 178 GLSAYA--------------------IQDNVIPFI--------SGEEWKIENESKKIMGK 209
G+ A I N IP I + EE K+ E++KI
Sbjct: 168 GIDELAGQTAKLLNGYPAETNTFSQQIAFNCIPQIDQFMDNGYTKEEMKMVWETQKI--- 224
Query: 210 LKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP-DIKSIREAIENFDPLK 262
S V RVPV +GH EAV VE P D + + + ++ D ++
Sbjct: 225 -----FNDPSIMVNPTCVRVPVFYGHAEAVHVETRAPIDAEQVMDMLDQTDGIE 273
>gb|AAC43367.1| (U25078) aspartate-semialdehyde dehydrogenase [Vibrio cholerae]
Length = 316
Score = 92.8 bits (227), Expect = 5e-18
Identities = 89/294 (30%), Positives = 134/294 (45%), Gaps = 62/294 (21%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKL--IASEKSAGKKY---GDLVEDSPEEFRDYY 58
VA+ GATG VG T +++L F V++L +ASE+S GK Y G V E D+
Sbjct: 7 VAIFGATGAVGETMLEVLQERE-FPVDELFLLASERSEGKTYRFNGKTVRVQNVEEFDWS 65
Query: 59 VISLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPVFTNARAHRYDEDVPILVPEVNK 118
+ + F + G +L P + V V N RYD D+P++VPEVN
Sbjct: 66 QVHIALF--SAGGELSAKWAPIAAEAGVV--------VIDNTSHFRYDFDIPLVVPEVNP 115
Query: 119 DHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGAGFS 177
+ + E + + I+ NPNCST + ++L P+ + GI+++ V T ++SGAG +
Sbjct: 116 E--AIAEFRNRN------IIANPNCSTIQMLVALKPIYDAVGIERINVTTYHSVSGAGKA 167
Query: 178 GLSAYA--------------------IQDNVIPFI--------SGEEWKIENESKKIMGK 209
G+ A I N IP I + EE K+ E++KI
Sbjct: 168 GIDELAGQTAKLLNGYPAETQAFSQQIAFNCIPQIDQFMDNGYTKEEMKMVWETQKI--- 224
Query: 210 LKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP-DIKSIREAIENFDPLK 262
S V RVPV +GH EAV VE P D + + + +E D ++
Sbjct: 225 -----FNDPSIMVNPTCVRVPVFYGHAEAVHVETRAPIDAEQVMDMLEQTDGIE 273
>pir||T35382 probable aspartate-semialdehyde dehydrogenase - Streptomyces
coelicolor >gi|5123889|emb|CAB45481.1| (AL079348)
putative aspartate-semialdehyde dehydrogenase
[Streptomyces coelicolor A3(2)]
Length = 362
Score = 91.7 bits (224), Expect = 1e-17
Identities = 109/375 (29%), Positives = 166/375 (44%), Gaps = 87/375 (23%)
Query: 4 VAVLGATGLVGRTFVKLLGGHP--WFKVEKLIASEKSAGKKY---GDLVEDSPEEFRDYY 58
+AV+GATG VG +++L H W + +LIAS +SAG+K G+ VE
Sbjct: 19 LAVVGATGAVGSVMLQILSQHADVWGDI-RLIASPRSAGRKLAVRGEEVE---------- 67
Query: 59 VISLNEFLENPGVDLVFNALPASISRD-VEEKLAQEIPVFTNARAHRYDEDVPILVPEVN 117
V++L+E + GVD+ +P ++ A+ V N+ A R D DVP++VPEVN
Sbjct: 68 VVALSEEAFD-GVDVAMFDVPDEVAAQWAPLAAAKGAVVVDNSGAFRMDPDVPLVVPEVN 126
Query: 118 KDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLR-NFGIKKVRVATMQAISGAGF 176
V+ + RG IV NPNC+T + ++L L FG++++ V++ QA+SGAG
Sbjct: 127 PH-----AVRMRPRG----IVANPNCTTLSMIVALGALHAEFGLRELVVSSYQAVSGAGR 177
Query: 177 SGLSAY---------------------AIQD-----------NVIPFI--------SGEE 196
G+ A+ D NV+P+ S EE
Sbjct: 178 DGVDTLRRQLSLVAGTELGTHPGDVRRAVGDDTGPFPEPVALNVVPWAGSLREDGWSSEE 237
Query: 197 WKIENESKKIMGKLKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENPDIKSIREAIE 256
K+ +ES+KI+G + V RVPV+ H+ V E S++ A E
Sbjct: 238 MKVRDESRKILGL--------PNLPVAVTCVRVPVVTTHSLTVHARFEGE--VSVQGARE 287
Query: 257 NFDPLKDLKLPSYEKPIVYTEIPQPRLHRDRGRGLTVTVGRLERTSE---GVKYVALGHN 313
+ L ++ P E P P D VGR+ R + ++ G N
Sbjct: 288 ILATAPGVVL--FDNPAA-GEFPTP---ADAVGTDPTWVGRVRRALDDPTALELFVCGDN 341
Query: 314 LVRGAAGGSVLNAEL 328
L +GAA + AEL
Sbjct: 342 LRKGAALNTAQIAEL 356
>emb|CAB71815.1| (AL138662) aspartate semialdehyde dehydrogenase [Streptomyces
coelicolor A3(2)]
Length = 340
Score = 89.3 bits (218), Expect = 6e-17
Identities = 103/371 (27%), Positives = 152/371 (40%), Gaps = 86/371 (23%)
Query: 3 RVAVLGATGLVGRTFVKLLGGHPWFKVE-KLIASEKSAGKKY-GDLVEDSPEEFRDYYVI 60
RV ++GATG VG ++L + E +L AS +SAGK+ G VED+ DY
Sbjct: 2 RVGIVGATGQVGTVMRRILTERDFPVTELRLFASARSAGKELDGVTVEDAATA--DY--- 56
Query: 61 SLNEFLENPGVDLVFNALPASISRDVEEKLAQEIPV-FTNARAHRYDEDVPILVPEVNKD 119
G+D+V + + S+ + EK+A + PV N+ A R D +VP++V EVN
Sbjct: 57 --------SGLDIVLFSAGGATSKALAEKVASQGPVVIDNSSAWRRDPEVPLVVSEVNPH 108
Query: 120 HLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLR-NFGIKKVRVATMQAISGAGFSG 178
+ + +G I+ NPNC+T L PL G++ V VAT QA+SG+G +G
Sbjct: 109 -----AITDRPKG----IIANPNCTTMAAMPVLRPLHAEAGLEAVVVATYQAVSGSGLAG 159
Query: 179 LS-------------------------------AYAIQDNVIPFI----------SGEEW 197
+ I NV+P + EE
Sbjct: 160 VDELFEQVQKVGADAPKLTHDGSAVEFPKPDKYVAPIAYNVLPLAGSIVDDGLHETDEEQ 219
Query: 198 KIENESKKIMGKLKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENPDIKSIREAIEN 257
K+ NES+KI +E V RVPV GH+ + P S+ A E
Sbjct: 220 KLRNESRKI--------LEIPELKVSGTCVRVPVFSGHSLQINARFARP--ISVERAKE- 268
Query: 258 FDPLKDLKLPSYEKPIVYTEIPQPRLHRDRGRGLTVTVGRLERTSEGVKYVALGHNLVRG 317
L + + TE+P P + + + E G+ NL +G
Sbjct: 269 --------LLAGAPGVALTEVPTPLEAAGQDPSYVGRIRQDETVDNGLALFVSNDNLRKG 320
Query: 318 AAGGSVLNAEL 328
AA +V AEL
Sbjct: 321 AALNAVQIAEL 331
>gb|AAF79239.1|AC006917_24 (AC006917) F10B6.22 [Arabidopsis thaliana]
Length = 730
Score = 89.3 bits (218), Expect = 6e-17
Identities = 98/389 (25%), Positives = 166/389 (42%), Gaps = 88/389 (22%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPW-FKVEKLIASEKSAGKKYGDLVEDSPEEFRDYYVISL 62
+AV+G TG VG+ F+ +L + + K++AS++SAGK+ + +Y V L
Sbjct: 364 LAVVGVTGAVGQEFLSVLSDRDFPYSSIKMLASKRSAGKRVAF-------DGHEYTVEEL 416
Query: 63 NEFLENPGVDLVFNALPASISRDVEEKLAQE-IPVFTNARAHRYDEDVPILVPEVNKDHL 121
N GVD+ + SIS++ A++ V N+ A R + VP+++PEVN + +
Sbjct: 417 TADSFN-GVDIALFSAGGSISKEFGPLAAEKGTIVVDNSSAFRMVDGVPLVIPEVNPEAM 475
Query: 122 KLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRNFG-IKKVRVATMQAISGAGFSGLS 180
K ++V KG ++ NPNCST I +++ PL + +K++ V+T QA SGAG + +
Sbjct: 476 KGIKVGMG----KGALIANPNCSTIICLMAVTPLHHHAKVKRMVVSTYQAASGAGAAAME 531
Query: 181 ------------------------AYAIQDNVIPFISG----EEWKIENESKKI------ 206
A+ + + P + EE K+ E++KI
Sbjct: 532 ELVQQTREVLEGKPPTCNIFGQQYAFNLFSHNAPILDNGYNEEEMKLVKETRKIWVSGYL 591
Query: 207 ------------------MGKLKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENP-D 247
+ + V A RVPV+ H E+V ++ ENP D
Sbjct: 592 SAILCSFHFDLLFKNFRYLTPISCPSQNDTEVKVTATCIRVPVMRAHAESVNLQFENPLD 651
Query: 248 IKSIREAIENFDP---LKDLKLPSYEKPIVYTEIPQPRLHRDRGRGLTVTVGRLERT--- 301
+ RE ++ + D ++ P+ D V VGR+ R
Sbjct: 652 ENTAREILKKAPGVYIIDDRASNTFPTPL------------DVSNKDDVAVGRIRRDVSQ 699
Query: 302 --SEGVKYVALGHNLVRGAAGGSVLNAEL 328
+ G+ G + +GAA +V AE+
Sbjct: 700 DGNFGLDIFVCGDQIRKGAALNAVQIAEM 728
>gb|AAD49569.1|AF134837_3 (AF134837) aspartate-semialdehyde dehydrogenase [Amycolatopsis
mediterranei]
Length = 346
Score = 84.7 bits (206), Expect = 1e-15
Identities = 104/374 (27%), Positives = 154/374 (40%), Gaps = 86/374 (22%)
Query: 3 RVAVLGATGLVGRTFVKLLGGHPWFKVE-KLIASEKSAGKKYGDLVEDSPEEFRDYYVIS 61
RV V+GATG VG KLL + E + AS +SAG K +RD +
Sbjct: 6 RVGVVGATGQVGAVMRKLLAEREFPIAELRYFASARSAGSKL---------PWRDTEITI 56
Query: 62 LNEFLENP-GVDLVFNALPASISRDVEEKLAQE-IPVFTNARAHRYDEDVPILVPEVNKD 119
+ +P G+D+ + S S+ + A + V N+ A R D DVP++V EVN +
Sbjct: 57 EDASTADPSGLDIALFSAGGSTSKAQAPRFAAAGVTVIDNSSAFRMDPDVPLVVSEVNPE 116
Query: 120 HLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGAGFSG 178
V+ R+G I+ NPNC+T L PL + G+ ++ +T QA+SG+G +G
Sbjct: 117 -----AVKEARKG----IIANPNCTTIAAMPVLKPLHDEAGLVRLVASTYQAVSGSGLAG 167
Query: 179 LSAYA-------------------------------IQDNVIP----------FISGEEW 197
+ A I NV+P F + EE
Sbjct: 168 VDELAGQVRAAAEHASLLTHDGAAIDFPKPEKYVRPIAFNVLPMAGSIVDDGEFETDEEK 227
Query: 198 KIENESKKIMGKLKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENPDIKSIREAIEN 257
K NES+KI + V RVPV GH+ +V E E P S+ A E
Sbjct: 228 KFRNESRKI--------LSIPGLAVSCTCVRVPVFSGHSVSVNAEFERP--LSVERATE- 276
Query: 258 FDPLKDLKLPSYEKPIVYTEIPQPRLHRDRGRGLTVTVGRLERTSEGVKYVAL---GHNL 314
L ++ + +E P P + R++ EG + +AL NL
Sbjct: 277 --------LLTHAPGVELSEEPTPLQAAGNDPSYVGRI-RVDPGVEGGRGLALFLSNDNL 327
Query: 315 VRGAAGGSVLNAEL 328
+GAA ++ AEL
Sbjct: 328 RKGAALNAIQIAEL 341
>sp|Q9ZDL2|DHAS_RICPR ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA DEHYDROGENASE) (ASADH)
>gi|7431503|pir||F71687 aspartate-semialdehyde
dehydrogenase (asd) RP316 - Rickettsia prowazekii
>gi|3860876|emb|CAA14776.1| (AJ235271)
ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (asd) [Rickettsia
prowazekii]
Length = 338
Score = 81.5 bits (198), Expect = 1e-14
Identities = 90/342 (26%), Positives = 146/342 (42%), Gaps = 73/342 (21%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPWFKVEKL--IASEKSAGK--KYGDLVEDSPEEFRDYYV 59
+AV+GATG VGR + +L F + K+ IAS+ S G+ ++G+ + ++
Sbjct: 7 IAVIGATGNVGRETLNILAERH-FPINKIYAIASDNSLGREVRFGEKI---------LHI 56
Query: 60 ISLNEFLENPGVDLVFNALPASISRDVEEKLAQ-EIPVFTNARAHRYDEDVPILVPEVNK 118
S+ F + +++ F +++S++ K V R D VP++VPEVN
Sbjct: 57 NSIKIFNFHD-IEIAFFCAGSNVSKEFIPKATSCNCIVIDKTSLFRADNQVPLIVPEVNL 115
Query: 119 DHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGAGFS 177
LK + I+ NPNC L + L PL N IK+V ++T Q++SGAG +
Sbjct: 116 STLKEFNTKN--------IIANPNCIVIPLVVVLKPLDNEIKIKRVVISTYQSVSGAGKA 167
Query: 178 GL--------SAYAIQD------------NVIPFI--------SGEEWKIENESKKIMGK 209
G+ S Y ++ N+ P+I + EE KI E KIMG
Sbjct: 168 GMDELYNQTKSKYVFRENNPKKFPKQIAFNLFPYIGDLNKDGYTSEETKIAFELNKIMGN 227
Query: 210 LKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELEN----PDIKSIREAIENFDPLKDLK 265
F + RVPV GH +V +E + D++ I + + + +
Sbjct: 228 ---------HFKTSVTSVRVPVFIGHAISVNIEFSDKIYAKDVEEILQDADGIVTISNNN 278
Query: 266 LPSYEKPI-------VYTEIPQPRLHRDRGRGLTVTVGRLER 300
+Y PI VY + L +D L +T L +
Sbjct: 279 GLAYISPIEVVGEDAVYVSRIRNDLSKDNTINLWITCDNLRK 320
>sp|P41404|DHAS_MYCSM ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA DEHYDROGENASE) (ASADH)
>gi|421606|pir||S31803 aspartate-semialdehyde
dehydrogenase (EC 1.2.1.11) - Mycobacterium smegmatis
>gi|7431498|pir||S42423 aspartate-semialdehyde
dehydrogenase (EC 1.2.1.11) - Mycobacterium smegmatis
>gi|44510|emb|CAA78986.1| (Z17372) semialdehyde
dehydrogenase [Mycobacterium smegmatis]
Length = 346
Score = 79.6 bits (193), Expect = 5e-14
Identities = 103/377 (27%), Positives = 156/377 (41%), Gaps = 85/377 (22%)
Query: 1 MKRVAVLGATGLVGRTFVKLLGGHPWFKVE--KLIASEKSAGKKYGDLVEDSPEEFRDYY 58
M + V+GATG GR ++ L F + AS +S GKK FR
Sbjct: 1 MVNIGVVGATGQ-GRQVMRNLLEQRNFPATSVRFFASPRSEGKKL---------TFRGQE 50
Query: 59 VISLNEFLENP-GVDLVFNALPASISRDVEEKLAQE-IPVFTNARAHRYDEDVPILVPEV 116
+ N +P G+D+ + A++SR + A+ + V N+ A R D DVP++V EV
Sbjct: 51 IEVENAETADPSGLDIALFSAGATMSRVQAPRFAEAGVIVVDNSSAFRKDPDVPLVVSEV 110
Query: 117 NKDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPL-RNFGIKKVRVATMQAISGAG 175
N D +V+ K+ KG I+ NPNC+T L PL G++++ V++ QA+SG+G
Sbjct: 111 NFDR----DVRGKKLA-KG-IIANPNCTTMAAMPVLKPLHEEAGLQRLIVSSYQAVSGSG 164
Query: 176 FSGLSAYA-------------------------------IQDNVIPFI----------SG 194
+G+ A I N++P +
Sbjct: 165 IAGVEELAGQARPVIDGVEQLVHDGSALQYPAPNKYVAPIAFNIVPLAGNYVDDGSGETD 224
Query: 195 EEWKIENESKKIMGKLKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENPDIKSIREA 254
E+ K+ NES+KI+G V RVPV GH+ ++ E P S+
Sbjct: 225 EDQKLRNESRKILG--------IPELLVSGTCVRVPVFSGHSLSINAEFSQP--ISVERT 274
Query: 255 IENFDPLKDLKLPSYEKPIVYTEIPQ---PRLHRDRGRGLTVTVGRLERTSEGVKYVALG 311
E +KL P+ I R+ +D G V GR G+ G
Sbjct: 275 KELLSAAAGVKLVDVPTPLAAAGIDDCLVGRIRQDPG----VPDGR------GLALFVSG 324
Query: 312 HNLVRGAAGGSVLNAEL 328
NL +GAA ++ AEL
Sbjct: 325 DNLRKGAALNTIQIAEL 341
>sp|Q53612|DHAS_STRAK ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA DEHYDROGENASE) (ASADH)
>gi|904039|gb|AAC44053.1| (U29446)
aspartate-semialdehyde dehydrogenase [Streptomyces
akiyoshiensis]
Length = 338
Score = 79.6 bits (193), Expect = 5e-14
Identities = 102/371 (27%), Positives = 151/371 (40%), Gaps = 86/371 (23%)
Query: 3 RVAVLGATGLVGRTFVKLLGGHPWFKVE-KLIASEKSAGKKY-GDLVEDSPEEFRDYYVI 60
RV ++GATG VG ++L + E +L AS +SAG + G VED+ DY
Sbjct: 2 RVGIVGATGQVGTVMRRILTERNFPVTELRLFASARSAGTELDGVTVEDAATA--DY--- 56
Query: 61 SLNEFLENPGVDLVFNALPASISRDVEEKLA-QEIPVFTNARAHRYDEDVPILVPEVNKD 119
G+D+V + + S+ + EK+A Q V N+ A R +VP++V EVN
Sbjct: 57 --------TGLDIVLFSAGGATSKALAEKVASQGAVVIDNSSAWRKHPEVPLVVSEVNPH 108
Query: 120 HLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGAGFSG 178
+K + +G I+ NPNC+T L PL + G++ + VAT QA+SG+G +G
Sbjct: 109 AIK-----DRPKG----IIANPNCTTMAAMPVLRPLHDEAGLEALVVATYQAVSGSGLAG 159
Query: 179 LSAY-------------------------------AIQDNVIPFI----------SGEEW 197
++ I NV+P + EE
Sbjct: 160 VAELHGQTQKVVADAEKLTHDGEAVDFPEPGVYKRPIAFNVLPLAGSIVDDGLNETDEEQ 219
Query: 198 KIENESKKIMGKLKGDEIEPASFDVIAIATRVPVIHGHTEAVFVELENPDIKSIREAIEN 257
K+ NES+KI +E V RVPV GH+ + P A
Sbjct: 220 KLRNESRKI--------LEIPGLKVSGTCVRVPVFSGHSLQINARFARP-----ISADGA 266
Query: 258 FDPLKDLKLPSYEKPIVYTEIPQPRLHRDRGRGLTVTVGRLERTSEGVKYVALGHNLVRG 317
+ LKD P E ++IP P + + E G+ NL +G
Sbjct: 267 TELLKD--APGVE----LSDIPTPLQAAGKDPSYVGRIRSDETVDNGLALFVSNDNLRKG 320
Query: 318 AAGGSVLNAEL 328
AA +V AEL
Sbjct: 321 AALNAVQIAEL 331
>emb|CAA80276.1| (Z22554) Asd protein [Bacillus subtilis]
Length = 208
Score = 78.0 bits (189), Expect = 1e-13
Identities = 70/221 (31%), Positives = 107/221 (47%), Gaps = 37/221 (16%)
Query: 4 VAVLGATGLVGRTFVKLLGGHPW-FKVEKLIASEKSAGKKYG------DLVEDSPEEFRD 56
VAV+GATG VG+ +K L + L++S+++AG K + E SPE F
Sbjct: 7 VAVVGATGAVGQQMLKTLEDRNFEMDTLTLLSSKRAAGTKVTFKGQELTVQEASPESFE- 65
Query: 57 YYVISLNEFLENPGVDLVFNALPASISRDVE-EKLAQEIPVFTNARAHRYDEDVPILVPE 115
GV++ + ++S+ + E + + V N A R DE+ P++VPE
Sbjct: 66 -------------GVNIALFSAGGTVSQALAPEAVKRGAIVIDNTSAFRMDENTPLVVPE 112
Query: 116 VNKDHLKLVEVQRKRRGWKGFIVTNPNCSTAILTLSLAPLRN-FGIKKVRVATMQAISGA 174
VN+ L + G I+ NPNCST + +L P+R +G+ KV V+T QA+SGA
Sbjct: 113 VNEADL------HEHNG----IIANPNCSTIQMVAALEPIRKAYGLNKVIVSTYQAVSGA 162
Query: 175 GFSGLSAYAIQDNVIPFISGEEWKIENESKKIMGKLKGDEI 215
G + Q I ++ EE IE E + G K +I
Sbjct: 163 GNEAVKELYSQTQAI--LNKEE--IEPEIMPVKGDKKHYQI 199
>sp|Q55512|DHAS_SYNY3 ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (ASA DEHYDROGENASE) (ASADH)
>gi|7427718|pir||S76022 aspartate-semialdehyde
dehydrogenase (EC 1.2.1.11) - Synechocystis sp. (strain
PCC 6803) >gi|1001379|dbj|BAA10869.1| (D64006) aspartate
beta-semialdehyde dehydrogenese [Synechocystis sp.]
Length = 280
Score = 69.9 bits (168), Expect = 4e-11
Identities = 79/293 (26%), Positives = 128/293 (42%), Gaps = 61/293 (20%)
Query: 70 GVDLVFNALPASISRDVEEKLAQEIPVFT-NARAHRYDEDVPILVPEVNKDHLKLVEVQR 128
G DLV + S S+ E++ + V N+ A R +VP++VPE+N E +
Sbjct: 8 GCDLVLASAGGSTSKRWAEEITKAGAVMVDNSSAFRMVPEVPLVVPEINP------EAAQ 61
Query: 129 KRRGWKGFIVTNPNCSTAILTLSLAPLRNFG-IKKVRVATMQAISGAGFSGLSA------ 181
+G I+ NPNC+T ++ +++ PL IK++ VAT Q+ SGAG +
Sbjct: 62 NHQG----IIANPNCTTILMGVAIYPLHQLQPIKRIVVATYQSASGAGAMAMEEVKHQSR 117
Query: 182 --------------YAIQDNVIPFISG--------EEWKIENESKKIMGKLKGDEIEPAS 219
Y + N+ P S EE K+ E++KI ++I
Sbjct: 118 DILEGKIPQAEILPYPLAFNLFPHNSPITANHYCEEEMKMVQETRKIFA---AEDIR--- 171
Query: 220 FDVIAIATRVPVIHGHTEAVFVELENP-DIKSIREAIENFDPLKDLKLPSYEKPIVYTEI 278
+ A RVPV+ H+EAV +E P ++ + AI +K + ++K Y +
Sbjct: 172 --ITATCVRVPVLRAHSEAVNLEFATPFPVELAKTAIAKAPGVK--LVEDWQKN--YFPM 225
Query: 279 PQPRLHRDRGRGLTVTVGRLERT---SEGVKYVALGHNLVRGAAGGSVLNAEL 328
P +D V VGR+ + G+ G + +GAA +V AEL
Sbjct: 226 PMDATGQD-----DVLVGRIRQDISHPNGLDLWLCGDQIRKGAALNAVQIAEL 273
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.318 0.138 0.395
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 125219522
Number of Sequences: 2977
Number of extensions: 5385112
Number of successful extensions: 14717
Number of sequences better than 1.0e-10: 58
Number of HSP's better than 0.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 14448
Number of HSP's gapped (non-prelim): 72
length of query: 335
length of database: 189,106,746
effective HSP length: 56
effective length of query: 279
effective length of database: 155,591,474
effective search space: 43410021246
effective search space used: 43410021246
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 165 (68.7 bits)