BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1679 (pgk) DE:3-phosphoglycerate kinase (pgk)
(410 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9UZW0|PGK_PYRAB PHOSPHOGLYCERATE KINASE >gi|7434540|pir||E75... 811 0.0
sp|O58965|PGK_PYRHO PHOSPHOGLYCERATE KINASE >gi|7434538|pir||D71... 723 0.0
sp|P50316|PGK_PYRWO PHOSPHOGLYCERATE KINASE >gi|2129422|pir||S68... 661 0.0
sp|Q58058|PGK_METJA PHOSPHOGLYCERATE KINASE >gi|2117896|pir||A64... 367 e-100
sp|P20971|PGK_METFE PHOSPHOGLYCERATE KINASE >gi|80951|pir||PN000... 357 1e-97
sp|O27121|PGK_METTH PHOSPHOGLYCERATE KINASE >gi|7434549|pir||B69... 351 6e-96
sp|P20972|PGK_METBR PHOSPHOGLYCERATE KINASE >gi|80906|pir||PN000... 346 3e-94
emb|CAB57772.1| (Y18930) phosphoglycerate kinase [Sulfolobus sol... 330 1e-89
emb|CAC12203.1| (AL445066) probable 3-phosphoglycerate kinase [T... 330 1e-89
gb|AAK40847.1| Phosphoglycerate kinase [Sulfolobus solfataricus] 330 1e-89
sp|P50317|PGK_SULSO PHOSPHOGLYCERATE KINASE >gi|2129446|pir||S63... 330 1e-89
gi|11498746 3-phosphoglycerate kinase (pgk) [Archaeoglobus fulgi... 284 1e-75
gb|AAG19584.1| (AE005048) glucose-6-phosphate isomerase; Pgk [Ha... 282 4e-75
sp|P40924|PGK_BACSU PHOSPHOGLYCERATE KINASE >gi|7434535|pir||C69... 265 9e-70
pdb|1VPE| Crystallographic Analysis Of Phosphoglycerate Kinase... 259 4e-68
pir||S54289 phosphoglycerate kinase (EC 2.7.2.3) / triose-phosph... 258 9e-68
sp|Q9YFS7|PGK_AERPE PHOSPHOGLYCERATE KINASE >gi|7434541|pir||B72... 257 1e-67
sp|P36204|PGKT_THEMA BIFUNCTIONAL PGK/TIM [INCLUDES: PHOSPHOGLYC... 256 3e-67
sp|P18912|PGK_BACST PHOSPHOGLYCERATE KINASE >gi|80216|pir||JQ139... 255 8e-67
sp|P24269|PGK_BACME PHOSPHOGLYCERATE KINASE >gi|66910|pir||KIBSG... 254 2e-66
emb|CAA53187.1| (X75437) 3-phosphoglycerate kinase [Thermotoga m... 254 2e-66
dbj|BAB07278.1| (AP001519) phosphoglycerate kinase [Bacillus hal... 250 2e-65
sp|O52632|PGK_CLOAB PHOSPHOGLYCERATE KINASE >gi|2829139|gb|AAC13... 250 2e-65
sp|Q9SBN4|PGKH_VOLCA PHOSPHOGLYCERATE KINASE, CHLOROPLAST PRECUR... 235 1e-60
sp|O66519|PGK_AQUAE PHOSPHOGLYCERATE KINASE >gi|7434532|pir||D70... 233 3e-60
pir||F82317 phosphoglycerate kinase VC0477 [imported] - Vibrio c... 232 5e-60
gb|AAB53931.1| (U28760) phosphoglycerate kinase [Borrelia burgdo... 231 1e-59
sp|Q59181|PGK_BORBU PHOSPHOGLYCERATE KINASE >gi|7434537|pir||H70... 228 7e-59
pir||E82020 phosphoglycerate kinase (EC 2.7.2.3) NMA0257 [import... 226 5e-58
sp|P43726|PGK_HAEIN PHOSPHOGLYCERATE KINASE >gi|1075145|pir||D64... 224 1e-57
pir||H81247 phosphoglycerate kinase NMB0010 [imported] - Neisser... 224 1e-57
pir||D75408 phosphoglycerate kinase - Deinococcus radiodurans (s... 222 4e-57
sp|P11665|PGK_ECOLI PHOSPHOGLYCERATE KINASE >gi|66907|pir||TVECG... 219 5e-56
gb|AAF45020.1|AF108451_1 (AF108451) phosphoglycerate kinase prec... 219 6e-56
sp|P12783|PGKY_WHEAT PHOSPHOGLYCERATE KINASE, CYTOSOLIC >gi|6691... 218 1e-55
sp|Q9Z5C4|PGK_STAAU PHOSPHOGLYCERATE KINASE >gi|4490614|emb|CAB3... 217 1e-55
sp|P50318|PGKH_ARATH PHOSPHOGLYCERATE KINASE, CHLOROPLAST >gi|21... 217 2e-55
sp|Q42962|PGKY_TOBAC PHOSPHOGLYCERATE KINASE, CYTOSOLIC >gi|7434... 217 2e-55
sp|O32756|PGK_LACDE PHOSPHOGLYCERATE KINASE >gi|7434542|pir||T09... 217 2e-55
gb|AAF70258.1|AF247558_1 (AF247558) phosphoglycerate kinase [Ara... 217 2e-55
pir||F83577 phosphoglycerate kinase PA0552 [imported] - Pseudomo... 217 2e-55
gb|AAF85975.1|AF275639_1 (AF275639) cytosolic phosphoglycerate k... 216 3e-55
gb|AAD30221.1|AC007202_3 (AC007202) Is a member of the PF|00162 ... 216 4e-55
dbj|BAA33802.1| (AB018411) cytosolic phosphoglycerate kinase 1 [... 215 5e-55
gb|AAF45021.1|AF108452_1 (AF108452) phosphoglycerate kinase prec... 215 9e-55
sp|P29409|PGKH_SPIOL PHOSPHOGLYCERATE KINASE, CHLOROPLAST PRECUR... 214 2e-54
dbj|BAA33801.1| (AB018410) cytosolic phosphoglycerate kinase 1 [... 214 2e-54
sp|Q42961|PGKH_TOBAC PHOSPHOGLYCERATE KINASE, CHLOROPLAST PRECUR... 213 3e-54
gb|AAG29665.1|AC069159_21 (AC069159) phosphoglycerate kinase, pu... 212 5e-54
pir||S44063 phosphoglycerate kinase (EC 2.7.2.3) - Rhizopus niveus 212 8e-54
sp|P12782|PGKH_WHEAT PHOSPHOGLYCERATE KINASE, CHLOROPLAST PRECUR... 211 1e-53
sp|P29406|PGK2_RHINI PHOSPHOGLYCERATE KINASE 2 >gi|218041|dbj|BA... 211 1e-53
pir||T07014 phosphoglycerate kinase (EC 2.7.2.3) precursor, chlo... 211 1e-53
sp|Q9Z519|PGK_STRCO PHOSPHOGLYCERATE KINASE >gi|7480321|pir||T36... 210 2e-53
sp|P41758|PGKH_CHLRE PHOSPHOGLYCERATE KINASE, CHLOROPLAST PRECUR... 210 3e-53
dbj|BAA33803.1| (AB018412) chloroplast phosphoglycerate kinase [... 208 7e-53
sp|P29405|PGK1_RHINI PHOSPHOGLYCERATE KINASE 1 >gi|1084488|pir||... 208 9e-53
pir||S26623 phosphoglycerate kinase (EC 2.7.2.3) - spinach (frag... 208 1e-52
gb|AAC63499.1| (AF052407) phosphoglycerate kinase [Trypanoplasma... 208 1e-52
sp|P57525|PGK_BUCAI PHOSPHOGLYCERATE KINASE >gi|10039114|dbj|BAB... 208 1e-52
sp|P07377|PGKB_TRYBB PHOSPHOGLYCERATE KINASE, CYTOSOLIC (B) (ALL... 207 2e-52
emb|CAB95362.1| (AL359782) phosphoglycerate kinase [Trypanosoma ... 206 3e-52
pir||TVUTGB phosphoglycerate kinase (EC 2.7.2.3), glycosomal (al... 206 4e-52
sp|P07378|PGKC_TRYBB PHOSPHOGLYCERATE KINASE, GLYCOSOMAL (C) >gi... 206 4e-52
gb|AAA32121.1| (M33775) phosphoglycerate kinase (gPGK; E.C. 2.7.... 205 6e-52
sp|P74421|PGK_SYNY3 PHOSPHOGLYCERATE KINASE 205 6e-52
pdb|16PK| Phosphoglycerate Kinase From Trypanosoma Brucei Bisu... 205 6e-52
pir||B81285 phosphoglycerate kinase (EC 2.7.2.3) Cj1402c [import... 205 1e-51
gb|AAF71544.1|AF256214_1 (AF256214) phosphoglycerate kinase; Pgk... 205 1e-51
sp|P09403|PGK_THETH PHOSPHOGLYCERATE KINASE >gi|66909|pir||TVTWG... 204 1e-51
sp|P46273|PGK_CANAL PHOSPHOGLYCERATE KINASE >gi|799385|gb|AAA665... 204 1e-51
emb|CAB61570.1| (AJ251129) phosphoglycerate kinase [Pseudomonas ... 204 2e-51
sp|Q27683|PGKB_LEIMA PHOSPHOGLYCERATE KINASE, CYTOSOLIC (B) >gi|... 203 2e-51
sp|P50312|PGKC_LEIMA PHOSPHOGLYCERATE KINASE, GLYCOSOMAL (C) >gi... 203 2e-51
sp|P08966|PGKB_CRIFA PHOSPHOGLYCERATE KINASE, CYTOSOLIC (B) >gi|... 203 4e-51
sp|P08967|PGKC_CRIFA PHOSPHOGLYCERATE KINASE, GLYCOSOMAL (C) >gi... 203 4e-51
sp|P08893|PGKE_TRYBB PHOSPHOGLYCERATE KINASE, CYTOSOLIC (B) (ALL... 203 4e-51
gb|AAA32120.1| (M33775) phosphoglycerate kinase [Trypanosoma bru... 203 4e-51
sp|P09404|PGK_ZYMMO PHOSPHOGLYCERATE KINASE >gi|66908|pir||KIZYG... 202 5e-51
sp|P41759|PGK_SCHMA PHOSPHOGLYCERATE KINASE >gi|556413|gb|AAA935... 202 5e-51
sp|P78018|PGK_MYCPN PHOSPHOGLYCERATE KINASE >gi|2146500|pir||S73... 202 5e-51
sp|P50314|PGK_XANFL PHOSPHOGLYCERATE KINASE >gi|475713|gb|AAA621... 202 7e-51
emb|CAB95363.1| (AL359782) phosphoglycerate kinase [Trypanosoma ... 201 9e-51
sp|P27362|PGK_PLAFA PHOSPHOGLYCERATE KINASE >gi|84239|pir||JU047... 201 2e-50
gi|10383781 3-phosphoglycerate kinase; Pgk1p [Saccharomyces cere... 199 5e-50
sp|P29407|PGK_YARLI PHOSPHOGLYCERATE KINASE >gi|2133236|pir||S68... 199 5e-50
sp|P50315|PGK_HALVA PHOSPHOGLYCERATE KINASE >gi|2147021|pir||S65... 199 5e-50
pdb|1QPG| 3-Phosphoglycerate Kinase, Mutation R65q 199 6e-50
sp|P47542|PGK_MYCGE PHOSPHOGLYCERATE KINASE >gi|1361751|pir||B64... 198 8e-50
sp|P41757|PGK_CANMA PHOSPHOGLYCERATE KINASE >gi|83923|pir||JT095... 198 1e-49
pdb|3PGK| Phosphoglycerate Kinase (E.C.2.7.2.3) Complex With A... 197 2e-49
sp|P50320|PGKP_ALCEU PHOSPHOGLYCERATE KINASE, PLASMID >gi|976369... 197 2e-49
sp|Q01655|PGK_CORGL PHOSPHOGLYCERATE KINASE >gi|419673|pir||B432... 197 2e-49
sp|Q27685|PGKC_LEIME PHOSPHOGLYCERATE KINASE, GLYCOSOMAL (C) >gi... 197 2e-49
sp|O74233|PGK_GLOMO PHOSPHOGLYCERATE KINASE >gi|3319309|gb|AAD09... 196 3e-49
pir||KIBYG phosphoglycerate kinase (EC 2.7.2.3) - yeast (Sacchar... 196 4e-49
gb|AAG34561.1|AF316577_1 (AF316577) phosphoglycerate kinase [Dic... 196 5e-49
sp|O94123|PGK_AGABI PHOSPHOGLYCERATE KINASE >gi|3873556|emb|CAA6... 195 7e-49
sp|P14828|PGK_KLULA PHOSPHOGLYCERATE KINASE >gi|66895|pir||KIVKG... 195 9e-49
sp|P33161|PGK_PENCI PHOSPHOGLYCERATE KINASE >gi|320113|pir||S289... 194 1e-48
pir||I39554 phosphoglycerate kinase (EC 2.7.2.3) - Alcaligenes e... 194 1e-48
sp|O60101|PGK_SCHPO PHOSPHOGLYCERATE KINASE >gi|7492300|pir||T39... 194 2e-48
sp|P41756|PGK_ASPOR PHOSPHOGLYCERATE KINASE >gi|541651|dbj|BAA05... 193 3e-48
pir||S76392 phosphoglycerate kinase (EC 2.7.2.3) - Synechocystis... 193 3e-48
sp|P91427|PGK_CAEEL PROBABLE PHOSPHOGLYCERATE KINASE >gi|7507007... 192 6e-48
sp|P50319|PGKC_ALCEU PHOSPHOGLYCERATE KINASE, CHROMOSOMAL >gi|21... 192 8e-48
sp|P41760|PGK1_TRYCO PHOSPHOGLYCERATE KINASE, CYTOSOLIC >gi|5678... 191 1e-47
sp|Q27684|PGKB_LEIME PHOSPHOGLYCERATE KINASE, CYTOSOLIC (B) >gi|... 191 1e-47
sp|P56154|PGK_HELPY PHOSPHOGLYCERATE KINASE >gi|7434530|pir||A64... 191 1e-47
pir||D82757 phosphoglycerate kinase XF0823 [imported] - Xylella ... 191 1e-47
sp|Q9Z7M5|PGK_CHLPN PHOSPHOGLYCERATE KINASE >gi|7434545|pir||C72... 190 2e-47
pir||PC1118 phosphoglycerate kinase (EC 2.7.2.3) 1 - tammar wall... 190 3e-47
sp|P29408|PGK1_MACEU PHOSPHOGLYCERATE KINASE 1 190 3e-47
sp|Q9ZJP1|PGK_HELPJ PHOSPHOGLYCERATE KINASE >gi|7434548|pir||B71... 189 4e-47
sp|P24590|PGK_TRIVI PHOSPHOGLYCERATE KINASE >gi|283403|pir||S253... 188 1e-46
pir||KIHOG phosphoglycerate kinase (EC 2.7.2.3) - horse 187 2e-46
gb|AAA39921.1| (M18654) testis-specific phosphoglycerate kinase ... 187 2e-46
sp|P00559|PGK_HORSE PHOSPHOGLYCERATE KINASE 187 3e-46
gi|4505763 phosphoglycerate kinase 1 [Homo sapiens] >gi|2144428|... 185 6e-46
pir||A24830 phosphoglycerate kinase (EC 2.7.2.3) - Emericella ni... 185 6e-46
sp|P00558|PGK1_HUMAN PHOSPHOGLYCERATE KINASE 1 (PRIMER RECOGNITI... 185 6e-46
sp|P50310|PGK_CRIGR PHOSPHOGLYCERATE KINASE >gi|2117894|pir||I48... 185 6e-46
gi|11419710 phosphoglycerate kinase 1 [Homo sapiens] 185 6e-46
sp|P16617|PGK2_RAT PHOSPHOGLYCERATE KINASE, TESTIS SPECIFIC >gi|... 185 8e-46
sp|P11977|PGK_EMENI PHOSPHOGLYCERATE KINASE >gi|168070|gb|AAA333... 185 8e-46
sp|O02608|PGK_EUPCR PHOSPHOGLYCERATE KINASE >gi|2109276|gb|AAB58... 185 8e-46
gi|6679291 phosphoglycerate kinase 1 [Mus musculus] >gi|129903|s... 184 1e-45
sp|O83549|PGK_TREPA PHOSPHOGLYCERATE KINASE >gi|7434533|pir||G71... 182 5e-45
sp|P38667|PGK_NEUCR PHOSPHOGLYCERATE KINASE >gi|11260667|pir||T4... 182 7e-45
gb|AAF73528.1| (AE002274) phosphoglycerate kinase [Chlamydia mur... 181 1e-44
gb|AAB41227.1| (U83197) 3-phosphoglycerate kinase [Chlamydia tra... 180 3e-44
emb|CAB61501.1| (AL049589) dJ570L12.1 (phosphoglycerate kinase 1... 179 4e-44
sp|P07205|PGK2_HUMAN PHOSPHOGLYCERATE KINASE, TESTIS SPECIFIC >g... 179 6e-44
sp|P50311|PGK_OPISI PHOSPHOGLYCERATE KINASE >gi|4204091|gb|AAD10... 175 9e-43
sp|O61471|PGK_APLCA PHOSPHOGLYCERATE KINASE >gi|3043929|gb|AAC13... 175 1e-42
prf||1107228A kinase,phosphoglycerate [Homo sapiens] 173 4e-42
gb|AAF02830.1|AC009894_1 (AC009894) phosphoglycerate kinase [Ara... 148 8e-35
gb|AAC37223.1| (L37337) phosphoglycerate kinase [Trypanosoma con... 95 2e-18
gb|AAA03386.1| (U02234) Homology to phosphoglycerate kinase X545... 78 1e-13
gb|AAB36526.1| (U76418) 3-phosphoglycerate kinase [Neisseria gon... 69 9e-11
>sp|Q9UZW0|PGK_PYRAB PHOSPHOGLYCERATE KINASE >gi|7434540|pir||E75080 3-phosphoglycerate
kinase (pgk) PAB1679 - Pyrococcus abyssi (strain Orsay)
>gi|5458458|emb|CAB49946.1| (AJ248286)
3-phosphoglycerate kinase (pgk) [Pyrococcus abyssi]
Length = 410
Score = 811 bits (2073), Expect = 0.0
Identities = 410/410 (100%), Positives = 410/410 (100%)
Query: 1 MFRLGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGK 60
MFRLGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGK
Sbjct: 1 MFRLGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGK 60
Query: 61 PYSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV 120
PYSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV
Sbjct: 61 PYSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV 120
Query: 121 KNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEA 180
KNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEA
Sbjct: 121 KNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEA 180
Query: 181 LMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGR 240
LMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGR
Sbjct: 181 LMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGR 240
Query: 241 KNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQ 300
KNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQ
Sbjct: 241 KNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQ 300
Query: 301 IMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGH 360
IMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGH
Sbjct: 301 IMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGH 360
Query: 361 SIASIQKYGIEGITHISTGGGAMLTFFAGEELPVLRALQISYEKFKEVKA 410
SIASIQKYGIEGITHISTGGGAMLTFFAGEELPVLRALQISYEKFKEVKA
Sbjct: 361 SIASIQKYGIEGITHISTGGGAMLTFFAGEELPVLRALQISYEKFKEVKA 410
>sp|O58965|PGK_PYRHO PHOSPHOGLYCERATE KINASE >gi|7434538|pir||D71065 probable
phosphoglycerate kinase - Pyrococcus horikoshii
>gi|3257635|dbj|BAA30318.1| (AP000005) 410aa long
hypothetical phosphoglycerate kinase [Pyrococcus
horikoshii]
Length = 410
Score = 723 bits (1845), Expect = 0.0
Identities = 352/408 (86%), Positives = 388/408 (94%)
Query: 1 MFRLGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGK 60
MFRL DFN+HNK VFLRVDLNSPMKDGKIISDARF+AVLPTI+YL+E+GA+VV+GTHQGK
Sbjct: 1 MFRLEDFNFHNKTVFLRVDLNSPMKDGKIISDARFKAVLPTIRYLIESGAKVVIGTHQGK 60
Query: 61 PYSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV 120
PYSEDY TTEEHAR+LS LL+QHVEY+EDIFGRYAREKI+ELK GE+A+LENLRFSAEEV
Sbjct: 61 PYSEDYTTTEEHARVLSELLDQHVEYIEDIFGRYAREKIKELKSGEVAILENLRFSAEEV 120
Query: 121 KNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEA 180
KNKPIEECEKTF VKKLSKVIDYVVNDAFA AHRSQPSLVGFARIKPMIMGFLME+EIEA
Sbjct: 121 KNKPIEECEKTFLVKKLSKVIDYVVNDAFATAHRSQPSLVGFARIKPMIMGFLMEKEIEA 180
Query: 181 LMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGR 240
LM+AYYSK+SP++YVLGGAKV+DSLKV ENVLRR AD++LTGGLVANVFTLAKGFDLGR
Sbjct: 181 LMRAYYSKDSPKIYVLGGAKVEDSLKVVENVLRRERADLVLTGGLVANVFTLAKGFDLGR 240
Query: 241 KNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQ 300
KN+EFMKKKGLL+ VKHAE+ILDEFYPY+RTPVDFA+DYKG+R EI LLSE R LL+ YQ
Sbjct: 241 KNVEFMKKKGLLDYVKHAEEILDEFYPYIRTPVDFAVDYKGERVEIDLLSENRGLLHQYQ 300
Query: 301 IMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGH 360
IMDIG RT EKYR+I+MKA+++VANGPMGVFEREEFA+GTVEVFKAIA+S AFSVLGGGH
Sbjct: 301 IMDIGKRTAEKYREILMKARIIVANGPMGVFEREEFAIGTVEVFKAIADSPAFSVLGGGH 360
Query: 361 SIASIQKYGIEGITHISTGGGAMLTFFAGEELPVLRALQISYEKFKEV 408
SIASIQKYGI GITHISTGGGAML+FFAGEELPVLRALQISYEKFKEV
Sbjct: 361 SIASIQKYGITGITHISTGGGAMLSFFAGEELPVLRALQISYEKFKEV 408
>sp|P50316|PGK_PYRWO PHOSPHOGLYCERATE KINASE >gi|2129422|pir||S68188 phosphoglycerate
kinase (EC 2.7.2.3) [validated] - Pyrococcus woesei
>gi|1054832|emb|CAA51930.1| (X73527) phosphoglycerate
kinase [Pyrococcus woesei]
Length = 410
Score = 661 bits (1686), Expect = 0.0
Identities = 322/408 (78%), Positives = 373/408 (90%)
Query: 1 MFRLGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGK 60
MFRL DF Y+N+ VFLRVDLNSPM +GKIISDARFRAVLPTIKYL+E+GA+VVVGTHQGK
Sbjct: 1 MFRLRDFEYYNRTVFLRVDLNSPMSNGKIISDARFRAVLPTIKYLIESGAKVVVGTHQGK 60
Query: 61 PYSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV 120
PYSE+Y+TTEEHARILS LLN HVEYVEDIFG+YARE+I+ +KPGE+ +LENLRFSAEEV
Sbjct: 61 PYSEEYSTTEEHARILSELLNMHVEYVEDIFGKYARERIKAMKPGEVIVLENLRFSAEEV 120
Query: 121 KNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEA 180
KN IEECEKTFFV+KLS+VID VVNDAFAAAHRSQPSLVGFARIKPMIMGFLME+E++A
Sbjct: 121 KNATIEECEKTFFVRKLSQVIDLVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEKEVDA 180
Query: 181 LMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGR 240
L KAY S+E PRVYVLGGAKVDDSLKVAENVLR+ AD+ILTGGLV +FTLAKGFDLGR
Sbjct: 181 LTKAYESEEKPRVYVLGGAKVDDSLKVAENVLRKEKADLILTGGLVGQLFTLAKGFDLGR 240
Query: 241 KNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQ 300
+NI+F++KKG+L+ V AEKILDEFYPYVRTPVDFAID+KG+R EI LLS+++ L ++Y
Sbjct: 241 ENIKFLEKKGILKYVDWAEKILDEFYPYVRTPVDFAIDFKGERVEIDLLSDEKRLFDEYP 300
Query: 301 IMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGH 360
I+DIGSRT+EKYR+I++KA+++VANGPMGVFEREEFA+GT+ VFKAI ES AFSV+GGGH
Sbjct: 301 ILDIGSRTVEKYREILLKARIIVANGPMGVFEREEFAVGTIGVFKAIGESPAFSVIGGGH 360
Query: 361 SIASIQKYGIEGITHISTGGGAMLTFFAGEELPVLRALQISYEKFKEV 408
SIASI KY I GI+HISTGGGAMLTFFAGE+LPVL AL+ISYEKF +
Sbjct: 361 SIASIYKYNITGISHISTGGGAMLTFFAGEKLPVLEALKISYEKFSNL 408
>sp|Q58058|PGK_METJA PHOSPHOGLYCERATE KINASE >gi|2117896|pir||A64380 phosphoglycerate
kinase (EC 2.7.2.3) - Methanococcus jannaschii
>gi|1592299|gb|AAB98636.1| (U67512) phosphoglycerate
kinase (pgk) [Methanococcus jannaschii]
Length = 417
Score = 367 bits (931), Expect = e-100
Identities = 193/413 (46%), Positives = 281/413 (67%), Gaps = 14/413 (3%)
Query: 4 LGDFNYHNKVVFLRVDLNSPM--KDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKP 61
L DFN+ +K V LRVD+N P+ G+I+ D R R + TI L+ GA+VV+ HQ +P
Sbjct: 7 LDDFNFEDKRVVLRVDINCPIDPNTGEILDDKRIREIKSTITELINKGAKVVILAHQSRP 66
Query: 62 YSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV- 120
+D+ T + HA++LS+++ + VEY++++ G ARE I +K G++ +LEN+RF +EEV
Sbjct: 67 GKKDFTTLKNHAKVLSDVIGKEVEYIDEVIGSTAREAIINMKCGDVILLENVRFYSEEVL 126
Query: 121 ------KNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLM 174
+N ++ +T +K+L+ + DY VNDAFAAAHR+QPSLVGF+ PMI G LM
Sbjct: 127 SDWKKWENITPKKQAETNLIKRLAPLFDYFVNDAFAAAHRAQPSLVGFSYYMPMIAGRLM 186
Query: 175 EREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAK 234
ERE+ L K + E P VYVLGGAK DDS++V +NVL G AD +LT G+VAN+F +A
Sbjct: 187 EREVGVLSKVLENPEKPCVYVLGGAKADDSIRVMKNVLENGTADKVLTSGIVANIFLVAM 246
Query: 235 GFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRE 294
G+DLG N++ ++ GL ++ A+++L++F + PVD A++ +R E L +++
Sbjct: 247 GYDLG-VNMDIIENLGLKSQIEIAKELLNKFEDKIVVPVDVALNINEERVEADLNKDEKV 305
Query: 295 LLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFS 354
++ I DIG +TIE Y +II +AK +VANGP GVFE+E FA GT E+ KAIA S+ FS
Sbjct: 306 ---EHLINDIGEKTIELYSEIINEAKTIVANGPAGVFEKEAFAKGTEELLKAIANSKGFS 362
Query: 355 VLGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRALQISYEKFK 406
V+GGGH A+ + +GI + I H+STGGGA L F AGE+LPV+ L+ SY+K+K
Sbjct: 363 VIGGGHLSAAAELFGIADKIDHVSTGGGATLDFLAGEKLPVIEMLKESYKKYK 415
>sp|P20971|PGK_METFE PHOSPHOGLYCERATE KINASE >gi|80951|pir||PN0008 phosphoglycerate
kinase (EC 2.7.2.3) [validated] - Methanothermus
fervidus (fragment) >gi|149808|gb|AAA72936.1| (M55529)
3-phosphoglycerate kinase [Methanothermus fervidus]
Length = 410
Score = 357 bits (906), Expect = 1e-97
Identities = 183/401 (45%), Positives = 264/401 (65%), Gaps = 8/401 (1%)
Query: 2 FRLGDFNYHNKVVFLRVDLNSPMKD--GKIISDARFRAVLPTIKYLLENGARVVVGTHQG 59
+ + DF+Y V +RVD+NSP+ G+I+ D R R T+K L++ A+V + HQ
Sbjct: 5 YTMDDFDYSGSRVLVRVDINSPVDPHTGRILDDTRMRLHSKTLKELVDENAKVAILAHQS 64
Query: 60 KPYSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE 119
+P D+ T EEH+++LSN+L+ V YVEDIFG ARE I+ ++ G+I +LEN+RF +EE
Sbjct: 65 RPGKRDFTTMEEHSKVLSNILDMPVTYVEDIFGCAARESIRNMENGDIILLENVRFYSEE 124
Query: 120 VKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIE 179
V + + +T V+KLS V+DY +NDAFAAAHRSQPSLVGF P G LMERE++
Sbjct: 125 VLKRDPKVQAETHLVRKLSSVVDYYINDAFAAAHRSQPSLVGFPLKLPSAAGRLMEREVK 184
Query: 180 ALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLG 239
L K + E P VY+LGG K+DDS+ + +N+L+ G AD ILT GLVANVF A G D+
Sbjct: 185 TLYKIIKNVEKPCVYILGGVKIDDSIMIMKNILKNGSADYILTSGLVANVFLEASGIDIK 244
Query: 240 RKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDY 299
KN + + +K + +K A+K+ D++ + TPVD AI+ G R ++ + + + ++
Sbjct: 245 EKNRKILYRKNYKKFIKMAKKLKDKYGEKILTPVDVAINKNGKRIDVPI-----DDIPNF 299
Query: 300 QIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGG 359
I DIG TI+ Y + I +AK + ANGP GVFE ++F++GT ++ AIA S AFSV+ GG
Sbjct: 300 PIYDIGMETIKIYAEKIREAKTIFANGPAGVFEEQQFSIGTEDLLNAIASSNAFSVIAGG 359
Query: 360 HSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRALQ 399
H A+ +K GI I HIS+GGGA + F +GEELP ++ L+
Sbjct: 360 HLAAAAEKMGISNKINHISSGGGACIAFLSGEELPAIKVLE 400
>sp|O27121|PGK_METTH PHOSPHOGLYCERATE KINASE >gi|7434549|pir||B69006 phosphoglycerate
kinase (EC 2.7.2.3) - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622146|gb|AAB85538.1| (AE000876) 3-phosphoglycerate
kinase [Methanobacterium thermoautotrophicum]
Length = 411
Score = 351 bits (892), Expect = 6e-96
Identities = 188/401 (46%), Positives = 256/401 (62%), Gaps = 8/401 (1%)
Query: 4 LGDFNYHNKVVFLRVDLNSPM--KDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKP 61
+ D K V +RVD+NSP+ DG I+ D R R TI+ L + GAR VV HQ +P
Sbjct: 13 MDDIEVTGKTVLVRVDINSPVDPNDGTILDDTRMRLHAETIRELSDRGARTVVMAHQSRP 72
Query: 62 YSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVK 121
D+ T E+HAR LS +L + V+YVEDIFG ARE I L GEI +LEN+RF +EEV
Sbjct: 73 GKNDFTTLEQHARALSGILRRPVKYVEDIFGSAARENISGLGDGEIILLENVRFYSEEVL 132
Query: 122 NKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEAL 181
+ EE +T V+KL+ ++DY +NDAFAAAHRSQPSLVGFA P G +MERE+ L
Sbjct: 133 KRDPEEQAETHLVRKLAPLLDYFINDAFAAAHRSQPSLVGFALRVPSAAGRVMERELRTL 192
Query: 182 MKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRK 241
A + E P VYVLGG KVDDS+ V +NVL G AD++LT GLVAN+F G +G+
Sbjct: 193 QGALENVERPCVYVLGGVKVDDSIMVMKNVLENGSADLVLTTGLVANIFLAGCGVKIGKV 252
Query: 242 NIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQI 301
N++F+K +G + +K A+K+ F + PVD A+ G R ++ + + + ++ I
Sbjct: 253 NMDFIKSRGYCDFIKVAKKLKKRFPERIVVPVDVAVCRDGKRVDVPV-----KKIPNHPI 307
Query: 302 MDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGHS 361
DIG TI+ Y I +A+ + ANGP GVFE +F++GT ++ AI+ SE FS++GGGH
Sbjct: 308 QDIGMETIKLYARRIREARTLFANGPAGVFENPDFSIGTEDILNAISSSEGFSIIGGGHL 367
Query: 362 IASIQKYGIE-GITHISTGGGAMLTFFAGEELPVLRALQIS 401
A+ K G E I HIS+GGGA ++ AGEELP +R L+ S
Sbjct: 368 AAAAVKMGFEDSINHISSGGGASISLLAGEELPAVRVLEES 408
>sp|P20972|PGK_METBR PHOSPHOGLYCERATE KINASE >gi|80906|pir||PN0007 phosphoglycerate
kinase (EC 2.7.2.3) - Methanobacterium bryantii
(fragment) >gi|149736|gb|AAA72937.1| (M55530)
3-phosphoglycerate kinase [Methanobacterium bryantii]
Length = 409
Score = 346 bits (878), Expect = 3e-94
Identities = 180/400 (45%), Positives = 259/400 (64%), Gaps = 8/400 (2%)
Query: 2 FRLGDFNYHNKVVFLRVDLNSPM--KDGKIISDARFRAVLPTIKYLLENGARVVVGTHQG 59
+ + DFN +K V +RVD+NSP+ G I+ D + + TI + + GA+ VV HQ
Sbjct: 6 YTIDDFNLEDKTVLVRVDINSPVDPSTGSILDDTKIKLHAETIDEISKKGAKTVVLAHQS 65
Query: 60 KPYSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE 119
+P +D+ T ++HA+ LSN+LN+ V+Y++DIFG ARE+I+ LK G+I +LEN+RF EE
Sbjct: 66 RPGKKDFTTLQQHAKALSNILNRPVDYIDDIFGTAAREEIKRLKKGDILLLENVRFYPEE 125
Query: 120 VKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIE 179
+ + + +T V+KL +ID +NDAFAAAHRSQPSLVGFA P G +ME+E++
Sbjct: 126 ILKRDPHQQAETHMVRKLYPIIDIFINDAFAAAHRSQPSLVGFAVKLPSGAGRIMEKELK 185
Query: 180 ALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLG 239
+L A + E P VYVLGG KVDDS+ V ENVLR G AD +LT GLVAN+F A G +LG
Sbjct: 186 SLYGAVDNAEKPCVYVLGGVKVDDSIMVLENVLRNGSADYVLTTGLVANIFLWASGINLG 245
Query: 240 RKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDY 299
+ N +F+ KG ++ V+ +++L+EF ++ P D A+ R E + + +
Sbjct: 246 KYNEDFIINKGYIDFVEKGKQLLEEFDGQIKMPDDVAVCVDNARVEYCTKN-----IPNK 300
Query: 300 QIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGG 359
I DIG+ TI +Y I AK + ANGP GVFE+E F++GT ++ IA S +S++GGG
Sbjct: 301 PIYDIGTNTITEYAKFIRDAKTIFANGPAGVFEQEGFSIGTEDILNTIASSNGYSIIGGG 360
Query: 360 HSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRAL 398
H A+ + G+ GITHIS+GGGA + AGE+LPV+ L
Sbjct: 361 HLAAAANQMGLSSGITHISSGGGASINLLAGEKLPVVEIL 400
>emb|CAB57772.1| (Y18930) phosphoglycerate kinase [Sulfolobus solfataricus]
Length = 415
Score = 330 bits (838), Expect = 1e-89
Identities = 174/401 (43%), Positives = 263/401 (65%), Gaps = 10/401 (2%)
Query: 4 LGDFNYHNKVVFLRVDLNSPM-KDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPY 62
+ D + +K V LR+D+NSP+ ++GKII D+R +A + TIK L+ G VV+ +HQG+P
Sbjct: 16 MDDIDIQSKKVLLRIDINSPVDENGKIIDDSRIKAHIGTIKELINKGNSVVLISHQGRPG 75
Query: 63 SEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKN 122
+D+ + EEHA+++S L++ V +V+D+ G YARE I++L+ I +L+N+R +EE+
Sbjct: 76 DKDFTSLEEHAKLISKYLDREVIFVDDVIGPYAREMIKKLENNGILLLDNIRLISEELIE 135
Query: 123 KPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEALM 182
P ++ K+F VKKL+ + D +NDAFA AHRSQPS+VGF P G +MERE+ AL
Sbjct: 136 APPQQHVKSFLVKKLAPLFDIYINDAFATAHRSQPSIVGFPLALPSAAGRVMEREVSALA 195
Query: 183 KAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKN 242
K + ++++P+++ LGG KV D++++ EN++R+ AD ILTGGLVA +F++AKG +L KN
Sbjct: 196 KIFNAEDTPKIFTLGGGKVHDTIRIIENLVRKRIADRILTGGLVAELFSVAKGMNLNPKN 255
Query: 243 IEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIM 302
+E ++K G+L L+ A K+L P + PVD+ ++ G+ ++ E + I
Sbjct: 256 MEILEKLGILSLIPRARKLLLSGAP-IEIPVDYKVEINGN-----VIEEPASKVTGI-IK 308
Query: 303 DIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGHSI 362
DIGS T E Y I AKVVV GPMGV E E F G+ V KA E + + ++GGGH I
Sbjct: 309 DIGSTTAEIYSSFIKDAKVVVLRGPMGVIEDERFKSGSKSVLKASLEGQGYVIIGGGHMI 368
Query: 363 ASI-QKYGIEGI-THISTGGGAMLTFFAGEELPVLRALQIS 401
+++ + I+ HISTGGGA+L F +GE LP L AL +S
Sbjct: 369 SALDEDMKIDSSKVHISTGGGALLLFLSGERLPALEALSMS 409
>emb|CAC12203.1| (AL445066) probable 3-phosphoglycerate kinase [Thermoplasma
acidophilum]
Length = 408
Score = 330 bits (838), Expect = 1e-89
Identities = 177/410 (43%), Positives = 266/410 (64%), Gaps = 12/410 (2%)
Query: 2 FRLGDFNYHNKVVFLRVDLNSPMKD--GKIISDARFRAVLPTIKYLLENGARVVVGTHQG 59
F + F+ K V+LRVD+N+P+ G+I+ RFRA + TI+ L ++VV+ HQ
Sbjct: 5 FLMNSFDLAGKTVYLRVDINAPVNPLTGEIMGIDRFRAHIDTIRNL--RNSKVVIVAHQS 62
Query: 60 KPYSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE 119
+P +D+ + +HA+ILS+LLN+ V++V+ +FG + E+ G+I MLEN RF +EE
Sbjct: 63 RPGKDDFISLRQHAQILSHLLNKRVQFVDQLFGSQVNRAVSEMSDGDIVMLENSRFYSEE 122
Query: 120 VKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIE 179
V IE E + V+ LS + DY + DAFAA HR+Q +LVGF RIKP I G L+ERE+
Sbjct: 123 VDLTTIESMESSNIVRSLSPLFDYFIIDAFAAIHRAQTTLVGFHRIKPNIAGTLIEREVS 182
Query: 180 ALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLG 239
+ + +E P++ +LGGAK++DS+ V+EN L RGF D ILTGG+VAN F A GFD+G
Sbjct: 183 MIERFRKIREKPKIAILGGAKIEDSIAVSENFLSRGFVDKILTGGVVANAFLWASGFDIG 242
Query: 240 RKNIEF-MKKKGLLE-LVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLN 297
+KN EF MK G E L+ IL ++ + P DF ++ G R +S ++ +
Sbjct: 243 KKNREFIMKNNGDYEKLLDKCRAILSKYGDKLVMPTDFVMNPSGQR-----ISINEKIPD 297
Query: 298 DYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLG 357
D + DIG TI +Y +II A+ + NGPMG++E E+++ GT EVF A+A S+AF + G
Sbjct: 298 DQILADIGLDTIVEYSEIIDGARAIFMNGPMGMYEIEDYSSGTREVFTAVAHSKAFKLAG 357
Query: 358 GGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRALQISYEKFK 406
GGH+++++ K G+ + I H STGGGA++++ +GE +PVL AL+ S + F+
Sbjct: 358 GGHTLSALDKLGLTKMIDHASTGGGALISYLSGETMPVLEALKESKKLFE 407
>gb|AAK40847.1| Phosphoglycerate kinase [Sulfolobus solfataricus]
Length = 415
Score = 330 bits (838), Expect = 1e-89
Identities = 174/401 (43%), Positives = 263/401 (65%), Gaps = 10/401 (2%)
Query: 4 LGDFNYHNKVVFLRVDLNSPM-KDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPY 62
+ D + +K V LR+D+NSP+ ++GKII D+R +A + TIK L+ G VV+ +HQG+P
Sbjct: 16 MDDIDIQSKKVLLRIDINSPVDENGKIIDDSRIKAHIGTIKELINKGNSVVLISHQGRPG 75
Query: 63 SEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKN 122
+D+ + EEHA+++S L++ V +V+D+ G YARE I++L+ I +L+N+R +EE+
Sbjct: 76 DKDFTSLEEHAKLISKYLDREVIFVDDVIGPYAREMIKKLENNGILLLDNIRLISEELIE 135
Query: 123 KPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEALM 182
P ++ K+F VKKL+ + D +NDAFA AHRSQPS+VGF P G +MERE+ AL
Sbjct: 136 APPQQHVKSFLVKKLAPLFDIYINDAFATAHRSQPSIVGFPLALPSAAGRVMEREVSALA 195
Query: 183 KAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKN 242
K + ++++P+++ LGG KV D++++ EN++R+ AD ILTGGLVA +F++AKG +L KN
Sbjct: 196 KIFNAEDTPKIFTLGGGKVHDTIRIIENLVRKRIADRILTGGLVAELFSVAKGMNLNPKN 255
Query: 243 IEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIM 302
+E ++K G+L L+ A K+L P + PVD+ ++ G+ ++ E + I
Sbjct: 256 MEILEKLGILSLIPRARKLLLSGAP-IEIPVDYKVEINGN-----VIEEPASKVTGI-IK 308
Query: 303 DIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGHSI 362
DIGS T E Y I AKVVV GPMGV E E F G+ V KA E + + ++GGGH I
Sbjct: 309 DIGSTTAEIYSSFIKDAKVVVLRGPMGVIEDERFKSGSKSVLKASLEGQGYVIIGGGHMI 368
Query: 363 ASI-QKYGIEGI-THISTGGGAMLTFFAGEELPVLRALQIS 401
+++ + I+ HISTGGGA+L F +GE LP L AL +S
Sbjct: 369 SALDEDMKIDSSKVHISTGGGALLLFLSGERLPALEALSMS 409
>sp|P50317|PGK_SULSO PHOSPHOGLYCERATE KINASE >gi|2129446|pir||S63528 phosphoglycerate
kinase (EC 2.7.2.3) - Sulfolobus solfataricus
>gi|996075|emb|CAA56459.1| (X80178) pgk [Sulfolobus
solfataricus]
Length = 408
Score = 330 bits (838), Expect = 1e-89
Identities = 174/401 (43%), Positives = 263/401 (65%), Gaps = 10/401 (2%)
Query: 4 LGDFNYHNKVVFLRVDLNSPM-KDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPY 62
+ D + +K V LR+D+NSP+ ++GKII D+R +A + TIK L+ G VV+ +HQG+P
Sbjct: 9 MDDIDIQSKKVLLRIDINSPVDENGKIIDDSRIKAHIGTIKELINKGNSVVLISHQGRPG 68
Query: 63 SEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKN 122
+D+ + EEHA+++S L++ V +V+D+ G YARE I++L+ I +L+N+R +EE+
Sbjct: 69 DKDFTSLEEHAKLISKYLDREVIFVDDVIGPYAREMIKKLENNGILLLDNIRLISEELIE 128
Query: 123 KPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEALM 182
P ++ K+F VKKL+ + D +NDAFA AHRSQPS+VGF P G +MERE+ AL
Sbjct: 129 APPQQHVKSFLVKKLAPLFDIYINDAFATAHRSQPSIVGFPLALPSAAGRVMEREVSALA 188
Query: 183 KAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKN 242
K + ++++P+++ LGG KV D++++ EN++R+ AD ILTGGLVA +F++AKG +L KN
Sbjct: 189 KIFNAEDTPKIFTLGGGKVHDTIRIIENLVRKRIADRILTGGLVAELFSVAKGMNLNPKN 248
Query: 243 IEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIM 302
+E ++K G+L L+ A K+L P + PVD+ ++ G+ ++ E + I
Sbjct: 249 MEILEKLGILSLIPRARKLLLSGAP-IEIPVDYKVEINGN-----VIEEPASKVTGI-IK 301
Query: 303 DIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGHSI 362
DIGS T E Y I AKVVV GPMGV E E F G+ V KA E + + ++GGGH I
Sbjct: 302 DIGSTTAEIYSSFIKDAKVVVLRGPMGVIEDERFKSGSKSVLKASLEGQGYVIIGGGHMI 361
Query: 363 ASI-QKYGIEGI-THISTGGGAMLTFFAGEELPVLRALQIS 401
+++ + I+ HISTGGGA+L F +GE LP L AL +S
Sbjct: 362 SALDEDMKIDSSKVHISTGGGALLLFLSGERLPALEALSMS 402
>gi|11498746 3-phosphoglycerate kinase (pgk) [Archaeoglobus fulgidus]
>gi|3122607|sp|O29119|PGK_ARCFU PHOSPHOGLYCERATE KINASE
>gi|7434539|pir||A69393 phosphoglycerate kinase (EC
2.7.2.3) - Archaeoglobus fulgidus
>gi|2649444|gb|AAB90100.1| (AE001025) 3-phosphoglycerate
kinase (pgk) [Archaeoglobus fulgidus]
Length = 407
Score = 284 bits (720), Expect = 1e-75
Identities = 159/402 (39%), Positives = 246/402 (60%), Gaps = 9/402 (2%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS 63
L D Y K V LRVD+N+P+ + I+ +RF + +PTI+ L ++ ++V+ HQ +P
Sbjct: 9 LDDIPYRGKHVLLRVDINAPIVNSTILDTSRFESHIPTIEALEDS--KLVLLAHQSRPGK 66
Query: 64 EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNK 123
+D+ + E HA LS LL + VEY+++IF + +I+E++ GE+ +LEN+RF +EE N+
Sbjct: 67 KDFTSLESHASTLSKLLGKRVEYIDEIFSKGVLRRIKEMENGEVILLENVRFYSEEQLNR 126
Query: 124 PIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEALMK 183
EE + V+KLS D VNDAF+A+HRS SLVGF + P ++G L+E E+ AL K
Sbjct: 127 SAEEHAECHMVRKLSTAFDLFVNDAFSASHRSHASLVGFVPVLPSVVGRLVENEVTALSK 186
Query: 184 AYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNI 243
E +++VLGGAK+ DS+KV +NVL A+ ++ G+VAN F + KG+D+G N
Sbjct: 187 P-LKGEGRKIFVLGGAKIKDSVKVLKNVLENNIAEKVVLTGVVANYFLMLKGYDIGEVNR 245
Query: 244 EFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIMD 303
+ ++ + IL ++ + P+D I+ G R +I L EK + Y+IMD
Sbjct: 246 KVVEDNKEDVSDEEMINILKKYSDKIILPIDLGIEKDGVRVDIPL--EKFD--GKYRIMD 301
Query: 304 IGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGHSIA 363
IG T+ + +II K VV NGP GVFE E F+LGT E+ +A A +SV+GGGH +
Sbjct: 302 IGLETVNQLSEIIPKYDYVVLNGPAGVFEDERFSLGTYEILRA-ATRAGYSVVGGGHIAS 360
Query: 364 SIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRALQISYEK 404
+ + +G+ + +HIST GGA + F +GE+L L ++ + K
Sbjct: 361 AARLFGLSDKFSHISTAGGACIRFLSGEKLVALEVIKEYWAK 402
>gb|AAG19584.1| (AE005048) glucose-6-phosphate isomerase; Pgk [Halobacterium sp.
NRC-1]
Length = 398
Score = 282 bits (715), Expect = 4e-75
Identities = 165/397 (41%), Positives = 230/397 (57%), Gaps = 5/397 (1%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKD-GKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPY 62
L D N+ + +RVD+NSP+ G + DAR RA + T+ LL ARV V HQG+P
Sbjct: 6 LDDLAAANRAIGVRVDINSPLTAAGGLADDARLRAHVDTLAELLAADARVAVLAHQGRPG 65
Query: 63 SEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKN 122
+++A E HA L LL+ V Y + F AR+ + +L PGE +LEN RF +EE
Sbjct: 66 GDEFARLERHADRLDALLDAPVSYCDATFSTGARDAVADLAPGEAVVLENTRFYSEEYMA 125
Query: 123 KPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEALM 182
E T V L+ +D VNDAFAAAHRSQPSLVGF + P G +ME E++AL
Sbjct: 126 FAPERAADTALVDGLAPALDAYVNDAFAAAHRSQPSLVGFPEVLPSYAGRVMEAELDAL- 184
Query: 183 KAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKN 242
+PR YV+GGAKV DS++VA + L G AD +L G+VANVF A G DLGR +
Sbjct: 185 SGVADTPTPRTYVVGGAKVPDSVEVAAHALSHGLADNVLVTGVVANVFLAATGVDLGRAS 244
Query: 243 IEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIM 302
+F+ ++ + A +L + PVD A++ G R E L ++ D +
Sbjct: 245 TDFIHERDYGTEIARAADLLAAHNDALHLPVDVAVERDGARCE--LSTDALPPAGDEAVC 302
Query: 303 DIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGHSI 362
DIGS T++ Y D++ ++ VV NGP GVFE + FA GT VF A +E E S++GGG +
Sbjct: 303 DIGSDTVDAYADVLADSETVVVNGPAGVFEDDLFADGTRGVFDAASEVE-HSIVGGGDTA 361
Query: 363 ASIQKYGIEGITHISTGGGAMLTFFAGEELPVLRALQ 399
A+I+++ I G H+STGGGA + +LP + AL+
Sbjct: 362 AAIRRFDITGFDHVSTGGGAAINLLTDADLPAVAALR 398
>sp|P40924|PGK_BACSU PHOSPHOGLYCERATE KINASE >gi|7434535|pir||C69675 phosphoglycerate
kinase (EC 2.7.2.3) pgk - Bacillus subtilis
>gi|2635906|emb|CAB15398.1| (Z99121) phosphoglycerate
kinase [Bacillus subtilis]
Length = 394
Score = 265 bits (669), Expect = 9e-70
Identities = 162/401 (40%), Positives = 243/401 (60%), Gaps = 21/401 (5%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS 63
L D + KVVF RVD N PMKDG++ D R RA LPTIK+L + GA+V++ +H G+P
Sbjct: 6 LKDIDVKGKVVFCRVDFNVPMKDGEVTDDTRIRAALPTIKHLADQGAKVLLASHLGRPKG 65
Query: 64 E---DYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV 120
E + T AR L LL + V+ ++ +G + +I E+K G++ +LEN+RF E
Sbjct: 66 EVVEELRLTPVAAR-LGELLGKEVKKADEAYGDAVKAQISEMKDGDVLVLENVRFYPGEE 124
Query: 121 KNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEA 180
KN P E K F +++ D VNDAF AAHR+ S G A P + GFLME+E++
Sbjct: 125 KNDP--ELAKAF-----AELADVYVNDAFGAAHRAHASTAGIAEHLPAVAGFLMEKELDV 177
Query: 181 LMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGR 240
L KA + + P ++GGAKV D + V E++L + D ++ GG +A F A G+++G+
Sbjct: 178 LGKAVSNPDRPFTAIIGGAKVKDKIGVIESLLDK--VDNLIIGGGLAYTFVKALGYEVGK 235
Query: 241 KNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLSEKRELLNDY 299
+E K + + A++ F Y+ V A D+ D +I +S E+ +D
Sbjct: 236 SLLEEDKIELAKSFMDRAKEKGVNF--YMPEDVLVADDFSNDANVKIVPIS---EIPSDL 290
Query: 300 QIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAES-EAFSVLGG 358
+ +DIG++T E Y D+I +K+VV NGPMGVFE + FA GT V +A+AE+ + +SV+GG
Sbjct: 291 EAIDIGTKTRETYADVIKNSKLVVWNGPMGVFEIDLFAQGTKAVAEALAEAKDTYSVIGG 350
Query: 359 GHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRAL 398
G S A+++K+G+ + ++HISTGGGA L F G+ELP + AL
Sbjct: 351 GDSAAAVEKFGLADKMSHISTGGGASLEFMEGKELPGVAAL 391
>pdb|1VPE| Crystallographic Analysis Of Phosphoglycerate Kinase From The
Hyperthermophilic Bacterium Thermotoga Maritima
Length = 398
Score = 259 bits (655), Expect = 4e-68
Identities = 164/404 (40%), Positives = 232/404 (56%), Gaps = 24/404 (5%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYSED 65
D + K V +RVD N P+KDG + D R RA LPTIKY LE GA+V++ +H G+P E
Sbjct: 7 DVDLKGKRVIMRVDFNVPVKDGVVQDDTRIRAALPTIKYALEQGAKVILLSHLGRPKGEP 66
Query: 66 YA--TTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNK 123
+ A+ LS LL + V++V + G ++ ++ELK GE+ +LEN RF E KN
Sbjct: 67 SPEFSLAPVAKRLSELLGKEVKFVPAVVGDEVKKAVEELKEGEVLLLENTRFHPGETKND 126
Query: 124 PIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEALMK 183
P K + + D VNDAF AHR+ S VG A+ P + GFLME+EI+ L K
Sbjct: 127 PE-------LAKFWASLADIHVNDAFGTAHRAHASNVGIAQFIPSVAGFLMEKEIKFLSK 179
Query: 184 AYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNI 243
Y+ E P V VLGGAKV D + V N++ + AD IL GG + F A G ++G +
Sbjct: 180 VTYNPEKPYVVVLGGAKVSDKIGVITNLMEK--ADRILIGGAMMFTFLKALGKEVGSSRV 237
Query: 244 EFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYK---GDREEIYLLSEKRELLNDYQ 300
E K ELV+ A++ E + PVD I K G +++ + + + +
Sbjct: 238 EEDKIDLAKELVEKAKEKGVE----IVLPVDAVIAQKIEPGVEKKVVRIDD--GIPEGWM 291
Query: 301 IMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIA---ESEAFSVLG 357
+DIG TIE ++ + AK VV NGPMGVFE ++FA GT +V AIA E A +V+G
Sbjct: 292 GLDIGPETIELFKQKLSDAKTVVWNGPMGVFEIDDFAEGTKQVALAIAALTEKGAITVVG 351
Query: 358 GGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRALQI 400
GG S A++ K+G+E +H+STGGGA L F G+ELP + +++I
Sbjct: 352 GGDSAAAVNKFGLEDKFSHVSTGGGASLEFLEGKELPGIASMRI 395
>pir||S54289 phosphoglycerate kinase (EC 2.7.2.3) / triose-phosphate isomerase
(EC 5.3.1.1) - Thermotoga maritima
Length = 654
Score = 258 bits (652), Expect = 9e-68
Identities = 162/404 (40%), Positives = 230/404 (56%), Gaps = 24/404 (5%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYSED 65
D + K V +RVD N P+KDG + D R RA LPTIKY LE GA+V++ +H G+P E
Sbjct: 8 DVDLKGKRVIMRVDFNVPVKDGVVQDDTRIRAALPTIKYALEQGAKVILLSHLGRPKGEP 67
Query: 66 YA--TTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNK 123
+ A+ LS LL + V++V + G ++ ++ELK GE+ +LEN RF E KN
Sbjct: 68 SPEFSLAPVAKRLSELLGKEVKFVPAVVGDEVKKAVEELKEGEVLLLENTRFHPGETKND 127
Query: 124 PIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEALMK 183
P K + + D VNDAF AHR+ S VG A+ P + GFLME+EI+ L K
Sbjct: 128 PE-------LAKFWASLADIHVNDAFGTAHRAHASNVGIAQFIPSVAGFLMEKEIKFLSK 180
Query: 184 AYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNI 243
Y+ E P V VLGGAKV D + V N++ + AD IL GG + F A G ++G +
Sbjct: 181 VTYNPEKPYVVVLGGAKVSDKIGVITNLMEK--ADRILIGGAMMFTFLKALGKEVGSSRV 238
Query: 244 EFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYK---GDREEIYLLSEKRELLNDYQ 300
E K ++L K + E + PVD I K G +++ + + + +
Sbjct: 239 EEDK----IDLAKELLEKAKEKGVEIVLPVDAVIAQKIEPGVEKKVVRIDD--GIPEGWM 292
Query: 301 IMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIA---ESEAFSVLG 357
+DIG TIE ++ + AK VV NGPMGVFE ++FA GT +V AIA E A +V+G
Sbjct: 293 GLDIGPETIELFKQKLSDAKTVVWNGPMGVFEIDDFAEGTKQVALAIAALTEKGAITVVG 352
Query: 358 GGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRALQI 400
GG S A++ K+G+E +H+STGGGA L F G+ELP + +++I
Sbjct: 353 GGDSAAAVNKFGLEDKFSHVSTGGGASLEFLEGKELPGIASMRI 396
>sp|Q9YFS7|PGK_AERPE PHOSPHOGLYCERATE KINASE >gi|7434541|pir||B72773 probable
phosphoglycerate kinase APE0173 - Aeropyrum pernix
(strain K1) >gi|5103563|dbj|BAA79084.1| (AP000058) 410aa
long hypothetical phosphoglycerate kinase [Aeropyrum
pernix]
Length = 410
Score = 257 bits (651), Expect = 1e-67
Identities = 153/409 (37%), Positives = 236/409 (57%), Gaps = 10/409 (2%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDG-KIISDARFRAVLPTIKYLLENGARVVVGTHQGKPY 62
L D + K V +R DLNSP+ +G +I+ D+R T++ L + GA VV +HQG+P
Sbjct: 8 LDDVDVRGKKVIVRFDLNSPVGNGGEILDDSRIAEAAGTLRELCDRGAAVVALSHQGRPL 67
Query: 63 SEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKN 122
D+ + E HA +LS V +V D+ G A + L+PGE +L+N R +E+
Sbjct: 68 ESDFVSLERHASLLSRYSGVEVRFVMDVIGPEALRTVASLRPGEAVLLDNTRIISEDFIE 127
Query: 123 KPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEALM 182
+ V +LSK+ + VN+AF+A+HRSQ S+VGF + P G ++E+EI +L
Sbjct: 128 AEGTVHARGIMVTRLSKLANMYVNEAFSASHRSQASIVGFPYVLPSAGGRVLEKEIRSLN 187
Query: 183 KAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKN 242
+A S E P+V VLGGAK+ D++++ + + G AD +LT GLV +F A+G+ L R
Sbjct: 188 RAVSSGERPKVVVLGGAKLKDAVRIVDYLSSSGVADEVLTTGLVGLLFLYARGYRLPRDV 247
Query: 243 IEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIM 302
+ ++KKG E + A +I++E VRTP+DF ++ GD+ IY+ + + L +
Sbjct: 248 TKLLEKKGGEEAIAKARRIVEE-GRRVRTPIDFVVEV-GDK--IYI--KPADELTEGVPK 301
Query: 303 DIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGH-- 360
DIG T+E +R + A+V+V GP GV E F GTVE+ KA S A++V GGGH
Sbjct: 302 DIGPSTVEYFRAKMRGARVIVMRGPAGVIEDPRFRRGTVELVKAALSSGAYTVFGGGHFR 361
Query: 361 -SIASIQKYGIEGITHISTGGGAMLTFFAGEELPVLRALQISYEKFKEV 408
+ + ++ + H+STGGGA+L + +G LP ++AL S F V
Sbjct: 362 AILRDLPEHLSSKVGHLSTGGGALLYYLSGRPLPGVKALVDSARIFNLV 410
>sp|P36204|PGKT_THEMA BIFUNCTIONAL PGK/TIM [INCLUDES: PHOSPHOGLYCERATE KINASE ;
TRIOSEPHOSPHATE ISOMERASE (TIM)] >gi|7462920|pir||G72344
phosphoglycerate kinase (EC 2.7.2.3) / triose-phosphate
isomerase (EC 5.3.1.1) - Thermotoga maritima (strain
MSB8) >gi|4981212|gb|AAD35771.1|AE001741_4 (AE001741)
phosphoglycerate kinase/triose-phosphate isomerase
[Thermotoga maritima]
Length = 654
Score = 256 bits (647), Expect = 3e-67
Identities = 161/402 (40%), Positives = 228/402 (56%), Gaps = 24/402 (5%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYSED 65
D + K V +RVD N P+KDG + D R RA LPTIKY LE GA+V++ +H G+P E
Sbjct: 8 DVDLKGKRVIMRVDFNVPVKDGVVQDDTRIRAALPTIKYALEQGAKVILLSHLGRPKGEP 67
Query: 66 YA--TTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNK 123
+ A+ LS LL + V++V + G ++ ++ELK GE+ +LEN RF E KN
Sbjct: 68 SPEFSLAPVAKRLSELLGKEVKFVPAVVGDEVKKAVEELKEGEVLLLENTRFHPGETKND 127
Query: 124 PIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEALMK 183
P K + + D VNDAF AHR+ S VG A+ P + GFLME+EI+ L K
Sbjct: 128 PE-------LAKFWASLADIHVNDAFGTAHRAHASNVGIAQFIPSVAGFLMEKEIKFLSK 180
Query: 184 AYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNI 243
Y+ E P V VLGGAKV D + V N++ + AD IL GG + F A G ++G +
Sbjct: 181 VTYNPEKPYVVVLGGAKVSDKIGVITNLMEK--ADRILIGGAMMFTFLKALGKEVGSSRV 238
Query: 244 EFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYK---GDREEIYLLSEKRELLNDYQ 300
E K ++L K + E + PVD I K G +++ + + + +
Sbjct: 239 EEDK----IDLAKELLEKAKEKGVEIVLPVDAVIAQKIEPGVEKKVVRIDD--GIPEGWM 292
Query: 301 IMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIA---ESEAFSVLG 357
+DIG TIE ++ + AK VV NGPMGVFE ++FA GT +V AIA E A +V+G
Sbjct: 293 GLDIGPETIELFKQKLSDAKTVVWNGPMGVFEIDDFAEGTKQVALAIAALTEKGAITVVG 352
Query: 358 GGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
GG S A++ K+G+E +H+STGGGA L F G+ELP + ++
Sbjct: 353 GGDSAAAVNKFGLEDKFSHVSTGGGASLEFLEGKELPGIASI 394
>sp|P18912|PGK_BACST PHOSPHOGLYCERATE KINASE >gi|80216|pir||JQ1399 phosphoglycerate
kinase (EC 2.7.2.3) - Bacillus stearothermophilus
>gi|576239|pdb|1PHP| 3-Phosphoglycerate Kinase (Pgk)
(E.C.2.7.2.3) >gi|48855|emb|CAA41093.1| (X58059)
3-phosphoglycerate kinase [Bacillus stearothermophilus]
Length = 394
Score = 255 bits (644), Expect = 8e-67
Identities = 152/398 (38%), Positives = 231/398 (57%), Gaps = 17/398 (4%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYSE- 64
D + K VF RVD N PM+ G I D R RA LPTI+YL+E+GA+V++ +H G+P +
Sbjct: 8 DVDVRGKRVFCRVDFNVPMEQGAITDDTRIRAALPTIRYLIEHGAKVILASHLGRPKGKV 67
Query: 65 -DYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNK 123
+ + A+ L LL + V + G + + L G++ +LEN+RF E KN
Sbjct: 68 VEELRLDAVAKRLGELLERPVAKTNEAVGDEVKAAVDRLNEGDVLLLENVRFYPGEEKND 127
Query: 124 PIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEALMK 183
P E K F +++ D VNDAF AAHR+ S G A P + GFLME+E+E L K
Sbjct: 128 P--ELAKAF-----AELADLYVNDAFGAAHRAHASTEGIAHYLPAVAGFLMEKELEVLGK 180
Query: 184 AYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNI 243
A + + P ++GGAKV D + V +N+L + D ++ GG +A F A G D+G+ +
Sbjct: 181 ALSNPDRPFTAIIGGAKVKDKIGVIDNLLEK--VDNLIIGGGLAYTFVKALGHDVGKSLL 238
Query: 244 EFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIMD 303
E K + ++ A++ FY PVD + + + + + D+ +D
Sbjct: 239 EEDKIELAKSFMEKAKEKGVRFY----MPVDVVVADRFANDANTKVVPIDAIPADWSALD 294
Query: 304 IGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAES-EAFSVLGGGHSI 362
IG +T E YRD+I ++K+VV NGPMGVFE + FA GT + +A+AE+ + +SV+GGG S
Sbjct: 295 IGPKTRELYRDVIRESKLVVWNGPMGVFEMDAFAHGTKAIAEALAEALDTYSVIGGGDSA 354
Query: 363 ASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRALQ 399
A+++K+G+ + + HISTGGGA L F G++LP + AL+
Sbjct: 355 AAVEKFGLADKMDHISTGGGASLEFMEGKQLPGVVALE 392
>sp|P24269|PGK_BACME PHOSPHOGLYCERATE KINASE >gi|66910|pir||KIBSGM phosphoglycerate
kinase (EC 2.7.2.3) - Bacillus megaterium
>gi|39643|emb|CAA38375.1| (X54519) PGK protein (AA 1 -
394) [Bacillus megaterium] >gi|143318|gb|AAA73203.1|
(M87647) phosphoglycerate kinase [Bacillus megaterium]
Length = 394
Score = 254 bits (641), Expect = 2e-66
Identities = 155/401 (38%), Positives = 239/401 (58%), Gaps = 21/401 (5%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS 63
L D + K VF RVD N PMKDGK+ + R RA +PTI+YL+E GA+V++ +H G+P
Sbjct: 6 LKDIDVKGKRVFCRVDFNVPMKDGKVTDETRIRAAIPTIQYLVEQGAKVILASHLGRPKG 65
Query: 64 E--DYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVK 121
E + A L LL + V ++ FG ++ I + G++ +LEN+RF E K
Sbjct: 66 EVVEELRLNAVAERLQALLGKDVAKADEAFGEEVKKTIDGMSEGDVLVLENVRFYPGEEK 125
Query: 122 NKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEAL 181
N P E K F +++ D VNDAF AAHR+ S G A+ P + GFLME+E++ L
Sbjct: 126 NDP--ELAKAF-----AELADVYVNDAFGAAHRAHASTEGIAQHIPAVAGFLMEKELDVL 178
Query: 182 MKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRK 241
KA + E P ++GGAKV D + V +++L + D ++ GG ++ F A G ++G+
Sbjct: 179 SKALSNPERPFTAIVGGAKVKDKIGVIDHLLDK--VDNLIIGGGLSYTFIKALGHEVGKS 236
Query: 242 NIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAI--DYKGDREEIYLLSEKRELLNDY 299
+E K + ++ A+K FY PVD + D+ D I ++S + ++ +D+
Sbjct: 237 LLEEDKIELAKSFMEKAKKNGVNFY----MPVDVVVADDFSND-ANIQVVSIE-DIPSDW 290
Query: 300 QIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAE-SEAFSVLGG 358
+ +D G +T E Y D+I +K+V+ NGPMGVFE + FA GT V +A+AE ++ +SV+GG
Sbjct: 291 EGLDAGPKTREIYADVIKNSKLVIWNGPMGVFELDAFANGTKAVAEALAEATDTYSVIGG 350
Query: 359 GHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRAL 398
G S A+++K+ + + ++HISTGGGA L F G+ELP + AL
Sbjct: 351 GDSAAAVEKFNLADKMSHISTGGGASLEFMEGKELPGVVAL 391
>emb|CAA53187.1| (X75437) 3-phosphoglycerate kinase [Thermotoga maritima]
Length = 390
Score = 254 bits (641), Expect = 2e-66
Identities = 160/397 (40%), Positives = 225/397 (56%), Gaps = 24/397 (6%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYSED 65
D + K V +RVD N P+KDG + D R RA LPTIKY LE GA+V++ +H G+P E
Sbjct: 8 DVDLKGKRVIMRVDFNVPVKDGVVQDDTRIRAALPTIKYALEQGAKVILLSHLGRPKGEP 67
Query: 66 YA--TTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNK 123
+ A+ LS LL + V++V + G ++ ++ELK GE+ +LEN RF E KN
Sbjct: 68 SPEFSLAPVAKRLSELLGKEVKFVPAVVGDEVKKAVEELKEGEVLLLENTRFHPGETKND 127
Query: 124 PIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEALMK 183
P K + + D VNDAF AHR+ S VG A+ P + GFLME+EI+ L K
Sbjct: 128 PE-------LAKFWASLADIHVNDAFGTAHRAHASNVGIAQFIPSVAGFLMEKEIKFLSK 180
Query: 184 AYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNI 243
Y+ E P V VLGGAKV D + V N++ + A+ IL GG + F A G ++G +
Sbjct: 181 VTYNPEKPYVVVLGGAKVSDKIGVITNLMEK--ANRILIGGAMMFTFLKALGKEVGSSRV 238
Query: 244 EFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYK---GDREEIYLLSEKRELLNDYQ 300
E K ++L K + E + PVD I K G +++ + + + +
Sbjct: 239 EEDK----IDLAKELLEKAKEKGVEIVLPVDAVIAQKIEPGVEKKVVRIDD--GIPEGWM 292
Query: 301 IMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIA---ESEAFSVLG 357
+DIG TIE ++ + AK VV NGPMGVFE ++FA GT +V AIA E A +V+G
Sbjct: 293 GLDIGPETIELFKQKLSDAKTVVWNGPMGVFEIDDFAEGTKQVALAIAALTEKGAITVVG 352
Query: 358 GGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELP 393
GG S A++ K+G+E +H+STGGGA L F G+ELP
Sbjct: 353 GGDSAAAVNKFGLEDKFSHVSTGGGASLEFLEGKELP 389
>dbj|BAB07278.1| (AP001519) phosphoglycerate kinase [Bacillus halodurans]
Length = 394
Score = 250 bits (632), Expect = 2e-65
Identities = 156/397 (39%), Positives = 226/397 (56%), Gaps = 17/397 (4%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYSE- 64
D K VF RVD N PMKDG + D R RA LPTI+ L E GAR+++ +H G+P E
Sbjct: 8 DVELQGKKVFCRVDFNVPMKDGVVTDDTRIRAALPTIQLLAEKGARIILASHLGRPKGEV 67
Query: 65 -DYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNK 123
+ + A L LL + V V G A + ELK G++ +LEN+RF E KN
Sbjct: 68 VEELRLDPVAARLQELLGKPVAKVNVAHGPEAEQAANELKDGDVLLLENVRFYPGEEKND 127
Query: 124 PIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEALMK 183
P E K F + + D VNDAF AAHR+ S G A + G LME+E+E L K
Sbjct: 128 P--ELAKAF-----ASLADVYVNDAFGAAHRAHASTEGIAHHVTAVAGLLMEKELEVLGK 180
Query: 184 AYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNI 243
A + E P ++GGAKV D + V EN+L + D ++ GG +A F A+G ++G+ +
Sbjct: 181 ALSNPERPFTAIIGGAKVKDKIGVIENLLDK--VDNLIIGGGLAYTFIKAQGHEIGKSLL 238
Query: 244 EFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIMD 303
E K L ++ A++ F YV A D+ D + + ++ D++ +D
Sbjct: 239 EADKMDLALSFMEKAKEKGVNF--YVPQDAIVADDFSNDANTKAV--DIDQIPADWEALD 294
Query: 304 IGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAE-SEAFSVLGGGHSI 362
IG +T E YR++I +K+V+ NGPMGVFE + FA GT V +A+A+ ++ +SV+GGG S
Sbjct: 295 IGPKTRETYRNVIQSSKLVIWNGPMGVFELDAFAGGTKAVAEALADANDTYSVIGGGDSA 354
Query: 363 ASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
A+++K+G+ ++HISTGGGA L F G+ LP + AL
Sbjct: 355 AAVEKFGLANQMSHISTGGGASLEFMEGKALPGVVAL 391
>sp|O52632|PGK_CLOAB PHOSPHOGLYCERATE KINASE >gi|2829139|gb|AAC13161.1| (AF043386)
phosphoglycerate kinase [Clostridium acetobutylicum]
Length = 397
Score = 250 bits (632), Expect = 2e-65
Identities = 158/404 (39%), Positives = 230/404 (56%), Gaps = 30/404 (7%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYSED 65
D + K V +R D N P+KDG I + R LPTIKYL E+G +V++ +H GK D
Sbjct: 10 DVDVKGKRVLVRCDFNVPLKDGVITDENRLNGALPTIKYLSEHGGKVILCSHLGKAKGPD 69
Query: 66 YATT-EEHARILSNLLNQHVEYVED--IFGRYAREKIQELKPGEIAMLENLRFSAEEVKN 122
+ T A+ LS LL + V++ D + G A++ + ELK GEI +LEN RF EE KN
Sbjct: 70 PSKTLAPVAKRLSELLGREVKFAADDTVVGENAKKAVAELKEGEIVLLENTRFRPEEGKN 129
Query: 123 KPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIEAL 181
F K L+ + D VNDAF AHR+ S VG + + + G+L+++E++ L
Sbjct: 130 DDA-------FSKDLASLADVYVNDAFGTAHRAHCSTVGVTKFVDTAVCGYLIQKELKFL 182
Query: 182 MKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRK 241
A + P V +LGGAKV D + V N+L + D ++ GG +A F A+G+ +G
Sbjct: 183 GSAVENPVRPFVAILGGAKVSDKINVINNLLEK--VDTLIIGGGMAYTFLKAQGYTIGTS 240
Query: 242 NIEFMKKKGLLELVKHAE----KILDEFYPYVRTPVDFAI--DYKGDREEIYLLSEKREL 295
+E K E+++ AE K+L P+D + ++K D + + +E +
Sbjct: 241 LLEADKVDYAKEMIEKAEAKGVKLL--------LPIDNIVGAEFKADTKAV--TTEDANI 290
Query: 296 LNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSV 355
Y +DIG +T + Y D + +AK VV NGPMGVFE E FA GT +V KA+AES+A +V
Sbjct: 291 PEGYMGLDIGPKTQKLYADAVKEAKTVVWNGPMGVFEFENFAKGTKDVAKAMAESDATTV 350
Query: 356 LGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRAL 398
+GGG S A++ + G + +THISTGGGA L F G+ELP + AL
Sbjct: 351 IGGGDSAAAVNQLGFGDKMTHISTGGGASLEFLEGKELPGIVAL 394
>sp|Q9SBN4|PGKH_VOLCA PHOSPHOGLYCERATE KINASE, CHLOROPLAST PRECURSOR
>gi|5902588|gb|AAD55564.1|AF110782_1 (AF110782)
phosphoglycerate kinase precursor [Volvox carteri f.
nagariensis]
Length = 462
Score = 235 bits (592), Expect = 1e-60
Identities = 151/405 (37%), Positives = 225/405 (55%), Gaps = 24/405 (5%)
Query: 4 LGDFNYHNKVVFLRVDLNSPM--KDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKP 61
LG + K VF+R DLN P+ K I D R RA +PT+KYLL+NGA+V++ +H G+P
Sbjct: 69 LGKADLEGKRVFVRADLNVPLDKKTLAITDDTRIRAAVPTLKYLLDNGAKVLLTSHLGRP 128
Query: 62 YS---EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAE 118
+ Y T AR LS LL + V+ V+D G + + LK GE+ +LEN+RF E
Sbjct: 129 KGGPEDKYRLTPVVAR-LSELLGKEVKKVDDCIGPSVEQAVASLKSGELLLLENVRFYKE 187
Query: 119 EVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMERE 177
E KN P F KKL+ D VNDAF AHR+ S G + +KP + GFL+++E
Sbjct: 188 EEKNDPE-------FAKKLASNADLYVNDAFGTAHRAHASTEGVTKFLKPSVAGFLLQKE 240
Query: 178 IEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFD 237
++ L A + + P V ++GG+KV + V E ++ + D I+ GG + F A+G
Sbjct: 241 LDYLDGAVSAPKRPFVAIVGGSKVSSKITVIEKLMEK--CDKIIIGGGMIFTFYKARGLK 298
Query: 238 LGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLN 297
+G +E K LEL K+ E I + P D + K D + +
Sbjct: 299 VGSSLVEEDK----LELAKNLEAIAKAKGVQLLLPSDVVVADKFDANANTQTVSVEAIPD 354
Query: 298 DYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAE---SEAFS 354
+ +DIG +I+ ++D + AK VV NGPMGVFE +FA+GTV + ++E A +
Sbjct: 355 GWMGLDIGPDSIKTFQDALADAKTVVWNGPMGVFEFPKFAVGTVAIANTLSELTPKGAIT 414
Query: 355 VLGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRAL 398
++GGG S+A++++ G+ E ++HISTGGGA L G+ LP + AL
Sbjct: 415 IIGGGDSVAAVEQAGVAEKMSHISTGGGASLELLEGKVLPGVAAL 459
>sp|O66519|PGK_AQUAE PHOSPHOGLYCERATE KINASE >gi|7434532|pir||D70311 probable
phosphoglycerate kinase (EC 2.7.2.3) - Aquifex aeolicus
>gi|2982854|gb|AAC06475.1| (AE000674) phosphoglycerate
kinase [Aquifex aeolicus]
Length = 397
Score = 233 bits (588), Expect = 3e-60
Identities = 142/396 (35%), Positives = 223/396 (55%), Gaps = 17/396 (4%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKD-GKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPY 62
L D + K V +RVD N P+ + G I+ D R RA LPT++YLL+ A+V++ +H G+P
Sbjct: 7 LRDVDVKGKRVLVRVDYNVPLDEQGNIVDDTRIRASLPTVEYLLDANAKVILMSHLGRPK 66
Query: 63 SEDYA-TTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVK 121
+ D + A+ LS +N+ V+ D G + + +K G++ +LENLRF EE
Sbjct: 67 NRDPKYSLAPVAKRLSRYINKEVKLAPDCVGEEVKRIVNSMKEGDVVLLENLRFHKEET- 125
Query: 122 NKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIEA 180
EC++ F ++L+ + + V DAF HR S+ + +KP +MGFL+E+EI
Sbjct: 126 -----ECDENF-ARELASLGEVYVADAFGTCHRKHASVYLVPKFLKPAVMGFLLEKEITY 179
Query: 181 LMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGR 240
KA + + P V +LGGAKV L+V +N++RR D + GG +A F A G+ +G
Sbjct: 180 FEKAMVAPQRPVVAILGGAKVSSKLEVIKNLIRR--VDKLFIGGAMAFTFLKAMGYKVGN 237
Query: 241 KNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQ 300
+E + +L+ A+K+ + Y PVDF I + + +E+ + +
Sbjct: 238 SLVEDDLQDVARDLIDVAKKLEIKLY----LPVDFVIGQEVSENTPTKVVPWQEIPDGWM 293
Query: 301 IMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGH 360
+DIG ++E ++II A+ +V NGPMGVFE ++F GT+EV K +A+S A ++ GGG
Sbjct: 294 GLDIGPVSVELVKEIISDAQTIVWNGPMGVFEIDKFKHGTIEVAKLLAQSSALTIAGGGD 353
Query: 361 SIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVL 395
+ +I K G+ +STGGGA L AG+ELP L
Sbjct: 354 TDHAIHKAGVYHAFDFVSTGGGAFLELLAGKELPCL 389
>pir||F82317 phosphoglycerate kinase VC0477 [imported] - Vibrio cholerae (group
O1 strain N16961) >gi|9654904|gb|AAF93650.1| (AE004134)
phosphoglycerate kinase [Vibrio cholerae]
Length = 392
Score = 232 bits (586), Expect = 5e-60
Identities = 155/407 (38%), Positives = 232/407 (56%), Gaps = 35/407 (8%)
Query: 1 MFRLGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGK 60
+ ++ D + K VF+R DLN P+KDGK+ SDAR A LPTIK+ LE GA+V+V +H G+
Sbjct: 8 VIKMIDLDLAGKRVFIRADLNVPVKDGKVTSDARILASLPTIKHCLEAGAKVMVTSHLGR 67
Query: 61 PYSEDYATTEEHARI-----LSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRF 115
P +YA EE + + L++ L+ V V+D EL GE+ +LEN+RF
Sbjct: 68 PTEGEYA--EEFSLLPVVNYLNDALDCEVRLVKDYLDGV------ELNAGELVVLENVRF 119
Query: 116 SAEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIM-GFLM 174
+ E KN+ KK + + D V DAF AHR+Q S G P+ G L+
Sbjct: 120 NKGEKKNEEA-------LSKKYAALCDVFVMDAFGTAHRAQASTHGVGMFAPIACAGPLL 172
Query: 175 EREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAK 234
E+EAL KA P V ++GG+KV L V E++ + AD ++ GG +AN F A
Sbjct: 173 ADELEALGKAMDKPARPMVAIVGGSKVSTKLTVLESLSK--IADQLVVGGGIANTFIAAA 230
Query: 235 GFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLSEKR 293
G ++G+ E +LV+ A+K+++E V T V A + + E EI +SE +
Sbjct: 231 GHNVGKSLYE-------ADLVETAKKLMEECAIPVATDVACAKAFDENAEAEIKHVSEVQ 283
Query: 294 ELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAF 353
+ D I D+G + + +I+ AK ++ NGP+GVFE + F GT + +AIA+SE F
Sbjct: 284 D---DDMIFDLGPNSTAELAEILKNAKTILWNGPVGVFEFKNFEAGTRGIAEAIAQSEGF 340
Query: 354 SVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRALQ 399
SV GGG ++A+I K+GI+ +++ISTGGGA L F G++LP + L+
Sbjct: 341 SVAGGGDTLAAIDKFGIKADVSYISTGGGAFLEFVEGKKLPAVEMLE 387
>gb|AAB53931.1| (U28760) phosphoglycerate kinase [Borrelia burgdorferi]
Length = 393
Score = 231 bits (582), Expect = 1e-59
Identities = 138/395 (34%), Positives = 221/395 (55%), Gaps = 16/395 (4%)
Query: 8 NYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYSEDYA 67
++ K +R D N P+K+G I D R RA L TI+YL E GAR+V+ +H G+P +
Sbjct: 11 SFAGKRALVRCDFNVPLKEGSISDDTRIRAALSTIEYLKERGARIVLVSHLGRPDGKKNP 70
Query: 68 --TTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPI 125
+ + A LS LL Q V+ + D G ++K G++ +LEN+RF AEE KN
Sbjct: 71 KYSLKPVANRLSELLGQDVKMLSDCIGSEVVNSTLQMKDGDVVLLENVRFYAEEEKN--- 127
Query: 126 EECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEALMKAY 185
+K F KKLS+ D VNDAF AAHR+ S VG A P + GFLME+E +L
Sbjct: 128 ---DKNF-AKKLSENGDVFVNDAFGAAHRAHASTVGVADYSPSVGGFLMEKEDNSLGGIL 183
Query: 186 YSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNIEF 245
+ E P V ++GG+KV + V E++L + ++V++ GG +A F ++G+ +G+ +E
Sbjct: 184 KNPERPSVSIIGGSKVSSKIAVLESLLSK--SNVVVIGGGMAYTFLHSEGYSIGKSLLE- 240
Query: 246 MKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIMDIG 305
+ + K E V P+D + ++ I + + + MDIG
Sbjct: 241 ---DEYIGIASSFLKKAKELGVKVILPLDHIVADDFNKNSIPEYIDSFNIPENKIGMDIG 297
Query: 306 SRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGHSIASI 365
+ T+++ +++ AK ++ NGP+GVFE + F+ GT +V + +A +V+GGG S+A++
Sbjct: 298 ANTLKEIENVVKTAKTIIWNGPLGVFEFDSFSKGTAKVAEMVASCSGLTVVGGGDSVAAV 357
Query: 366 QKYGI-EGITHISTGGGAMLTFFAGEELPVLRALQ 399
K+ + + ITH+STGGGA L + G LP ++ L+
Sbjct: 358 NKFNLSDKITHVSTGGGASLEYLEGRILPGIKVLE 392
>sp|Q59181|PGK_BORBU PHOSPHOGLYCERATE KINASE >gi|7434537|pir||H70106 phosphoglycerate
kinase (EC 2.7.2.3) (pgk) - Lyme disease spirochete
>gi|2687944|gb|AAC66451.1| (AE001119) phosphoglycerate
kinase (pgk) [Borrelia burgdorferi]
Length = 393
Score = 228 bits (576), Expect = 7e-59
Identities = 138/395 (34%), Positives = 221/395 (55%), Gaps = 16/395 (4%)
Query: 8 NYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYSEDYA 67
++ K +R D N P+K+G I D R RA L TI+YL E GAR+V+ +H G+P +
Sbjct: 11 SFAGKRALVRCDFNVPLKEGSISDDTRIRAALSTIEYLKERGARIVLVSHLGRPDGKKNP 70
Query: 68 --TTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPI 125
+ + A LS LL Q V+ + D G ++K G++ +LEN+RF AEE KN
Sbjct: 71 KYSLKPVANRLSELLGQDVKMLSDCIGSEVVNSTLQMKDGDVVLLENVRFYAEEEKN--- 127
Query: 126 EECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEALMKAY 185
+K F KKLS+ D VNDAF AAHR+ S VG A P + GFLME+E + L
Sbjct: 128 ---DKNF-AKKLSENGDVFVNDAFGAAHRAHASTVGVADYLPSVGGFLMEKEDKFLGGIL 183
Query: 186 YSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNIEF 245
+ E P V ++GG+KV + V E++L + ++V++ GG +A F ++G+ +G+ +E
Sbjct: 184 KNPERPFVSIIGGSKVSSKIAVLESLLSK--SNVVVIGGGMAYTFLHSEGYSIGKSLLE- 240
Query: 246 MKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIMDIG 305
+ + K E V P+D + ++ I + + + MDIG
Sbjct: 241 ---DEYIGIASSFLKKAKELGVKVILPLDHIVADDFNKNSIPEYIDSFNIPENKIGMDIG 297
Query: 306 SRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGHSIASI 365
+ T+++ +++ AK ++ NGP+GVFE + F+ GT +V + +A +V+GGG S+A++
Sbjct: 298 ANTLKEIENVVKTAKTIIWNGPLGVFEFDSFSKGTAKVAEMVASCSGLTVVGGGDSVAAV 357
Query: 366 QKYGI-EGITHISTGGGAMLTFFAGEELPVLRALQ 399
K+ + + ITH+STGGGA L + G LP ++ L+
Sbjct: 358 NKFNLSDKITHVSTGGGASLEYLEGRILPGIKVLE 392
>pir||E82020 phosphoglycerate kinase (EC 2.7.2.3) NMA0257 [imported] - Neisseria
meningitidis (group A strain Z2491)
>gi|7379019|emb|CAB83565.1| (AL162752) phosphoglycerate
kinase [Neisseria meningitidis Z2491]
Length = 392
Score = 226 bits (569), Expect = 5e-58
Identities = 144/405 (35%), Positives = 225/405 (55%), Gaps = 29/405 (7%)
Query: 3 RLGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPY 62
+L + N K V +R D+N P KDGKI D R RA + ++KY ++NGA V+V TH G+P
Sbjct: 5 KLTEQNVQGKTVLIRADMNVPFKDGKISDDTRIRASIASVKYCVDNGASVIVMTHLGRPT 64
Query: 63 SEDYATTEEHARI---LSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE 119
++ ++ A + L +LL + V+ + D RE L G++ ML+N+R + E
Sbjct: 65 EGEFHPEDDVAPVAAHLGSLLGKDVKVLNDW-----RENKPALNAGDVVMLQNVRINKGE 119
Query: 120 VKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIM-GFLMEREI 178
KN E K + + + D VNDAF AHR+Q S A+ P+ G LM E+
Sbjct: 120 KKNDL--ELGKAY-----ASLCDVFVNDAFGTAHRAQASTEAVAQAAPVACAGVLMAGEL 172
Query: 179 EALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDL 238
+AL KA P V ++ G+KV L + E++ + D ++ GG +AN F LA+G +
Sbjct: 173 DALGKALKQPARPMVAIVAGSKVSTKLTILESLADK--VDQLIVGGGIANTFLLAEGKAI 230
Query: 239 GRKNIEFMKKKGLLELVKHAEKILDEFYPY---VRTPVDFAIDYKGDREEIYLLSEKREL 295
G+ E +LV+ ++KI+ + V P D + + ++ + ++
Sbjct: 231 GKSLAEH-------DLVEESKKIMAKMAAKGGSVPLPTDVVVAKAFAADAEAVVKDIADV 283
Query: 296 LNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSV 355
D I+DIG ++ D++ A VV NGP+GVFE ++FA GT + +AIA+S+AFS+
Sbjct: 284 AEDDMILDIGPKSAAALADLLKAADTVVWNGPVGVFEFDQFAGGTKALAEAIAQSKAFSI 343
Query: 356 LGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRALQ 399
GGG ++A+I K+G+ E I +ISTGGGA L F G+ELP + AL+
Sbjct: 344 AGGGDTLAAIAKFGVTEQIGYISTGGGAFLEFLEGKELPAVAALE 388
>sp|P43726|PGK_HAEIN PHOSPHOGLYCERATE KINASE >gi|1075145|pir||D64074 phosphoglycerate
kinase (EC 2.7.2.3) - Haemophilus influenzae (strain Rd
KW20) >gi|1573508|gb|AAC22183.1| (U32734)
phosphoglycerate kinase (pgk) [Haemophilus influenzae
Rd]
Length = 386
Score = 224 bits (566), Expect = 1e-57
Identities = 145/403 (35%), Positives = 215/403 (52%), Gaps = 28/403 (6%)
Query: 1 MFRLGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGK 60
+ ++ D + K VF+R DLN P+KDGK+ SDAR RA +PT+K LE GA+V+V +H G+
Sbjct: 3 VIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARIRATIPTLKLALEKGAKVMVTSHLGR 62
Query: 61 PYSEDYATTEEHARILSNLLNQ--HVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAE 118
P ++ + ++ L N +V +D ++K GEI +LEN+R +
Sbjct: 63 PTEGEFKPEDSLQPVVDYLKNAGFNVRLEQDYLNGV------DVKDGEIVVLENVRVNKG 116
Query: 119 EVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIM-GFLMERE 177
E KN P KK + + D V DAF AHR+Q S G A P+ G L+ E
Sbjct: 117 EKKNDPE-------LGKKYAALCDVFVMDAFGTAHRAQASTYGVAEFAPIACAGPLLAAE 169
Query: 178 IEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFD 237
++AL KA P V ++GG+KV L+V ++ + AD I+ GG +AN F A G +
Sbjct: 170 LDALGKALKEPARPMVAIVGGSKVSTKLEVLNSLSK--IADQIIVGGGIANTFIAAAGHN 227
Query: 238 LGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLN 297
+G+ E L+ + K D + PVD + + E+ +
Sbjct: 228 VGKSLYE----ADLIPVAKELAANTD-----IPVPVDVRVGLEFSETAAATEKVVNEVKD 278
Query: 298 DYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLG 357
D I DIG ++ E+ +II AK V+ NGP+GVFE F GT + AIA S+AFS+ G
Sbjct: 279 DESIFDIGDKSAEQLAEIIKNAKTVLWNGPVGVFEFPHFRKGTEIISHAIANSDAFSIAG 338
Query: 358 GGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRALQ 399
GG ++A+I +GI + I++ISTGGGA L F G+ LP + L+
Sbjct: 339 GGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVEILE 381
>pir||H81247 phosphoglycerate kinase NMB0010 [imported] - Neisseria meningitidis
(group B strain MD58) >gi|7225235|gb|AAF40489.1|
(AE002359) phosphoglycerate kinase [Neisseria
meningitidis MC58]
Length = 403
Score = 224 bits (565), Expect = 1e-57
Identities = 148/416 (35%), Positives = 228/416 (54%), Gaps = 40/416 (9%)
Query: 3 RLGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPY 62
+L + N K V +R D+N P KDGKI D R RA L +IKY ++NGA V+V TH G+P
Sbjct: 5 KLTEQNVQGKTVLIRADMNVPFKDGKISDDTRIRASLASIKYCVDNGASVIVMTHLGRPT 64
Query: 63 SEDYATTEEHARI---LSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE 119
++ ++ A + L +LL + V+ + D RE L G++ ML+N+R + E
Sbjct: 65 EGEFHPEDDVAPVAAHLGSLLGKDVKVLNDW-----RENKPALNAGDVVMLQNVRINKGE 119
Query: 120 VKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIM-GFLMEREI 178
KN E K + + + D VNDAF AHR+Q S A+ P+ G LM E+
Sbjct: 120 KKNDL--ELGKAY-----ASLCDVFVNDAFGTAHRAQASTEAVAQAAPVACAGVLMAGEL 172
Query: 179 EALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDL 238
+AL KA P V ++ G+KV L + E++ + D ++ GG +AN F LA+G +
Sbjct: 173 DALGKALKQPARPMVAIVAGSKVSTKLTILESLADK--VDQLIVGGGIANTFLLAEGKAI 230
Query: 239 GRKNIEFMKKKGLLELVKHAEKILDEFYPY---VRTPVDFAID--YKGDREEIY------ 287
G+ E +LV+ ++KI+ + V P D + + D E +
Sbjct: 231 GKSLAEH-------DLVEESKKIMAKMAAKGGSVPLPTDVVVAKAFAADAEAVVKDIAAD 283
Query: 288 ---LLSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVF 344
++ + ++ D I+DIG ++ D++ A VV NGP+GVFE ++FA GT +
Sbjct: 284 AEAVVKDIADVAEDEMILDIGPKSAAALADLLKAAGTVVWNGPVGVFEFDQFAGGTKALA 343
Query: 345 KAIAESEAFSVLGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRALQ 399
+AIA+S+AFS+ GGG ++A+I K+G+ E I +ISTGGGA L F G+ELP + AL+
Sbjct: 344 EAIAQSKAFSIAGGGDTLAAIAKFGVTEQIGYISTGGGAFLEFLEGKELPAVAALE 399
>pir||D75408 phosphoglycerate kinase - Deinococcus radiodurans (strain R1)
>gi|6459094|gb|AAF10913.1|AE001980_8 (AE001980)
phosphoglycerate kinase [Deinococcus radiodurans]
Length = 411
Score = 222 bits (561), Expect = 4e-57
Identities = 152/407 (37%), Positives = 226/407 (55%), Gaps = 28/407 (6%)
Query: 1 MFRLGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGK 60
M L + K V +RVD N P+ DG + D R A +PTIK LL+ GA VV+ +H G+
Sbjct: 23 MQNLSQLDVKGKRVLVRVDYNVPVGDGVVQDDTRITASVPTIKKLLDGGASVVLMSHFGR 82
Query: 61 PYS--EDYATTEEHARILSNLLNQHVEYVEDIFGR-YAREKIQELKPGEIAMLENLRFSA 117
P + ED + + A +S L Q V+++ + G + +Q L+PGE+A+LEN+RF A
Sbjct: 83 PKNGPEDKYSLKPVAEAVSRALGQDVKFIPSLPGSDETLQAVQALRPGEVALLENVRFEA 142
Query: 118 EEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMERE 177
E KN KL+K+ D V DAF +AHR+ S+ G A P G L++ E
Sbjct: 143 GEEKNDAALN-------DKLAKLGDAFVLDAFGSAHRAHSSVSGVAGKLPHAAGGLLQSE 195
Query: 178 IEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFD 237
++AL K ++ E P V ++GGAKV D +KV EN+L + D +L GG + F A+G
Sbjct: 196 VDALGKLLHAPEHPYVVIIGGAKVSDKIKVIENLLPK--VDRMLIGGGMMFTFIKARGGQ 253
Query: 238 LGRKNIE---FMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRE 294
+G +E KGLLE K+ +K+L + T A + D + + ++ +
Sbjct: 254 IGNSLVEDDQLDLAKGLLE--KYGDKLL------LPTDAVAADKFAADAQSKVVPAD--Q 303
Query: 295 LLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIA--ESEA 352
+ + + +DIG T Y D + AK V NGPMGVFE ++FA GT V A+ + +A
Sbjct: 304 IPDGWMGLDIGPDTQRAYADALQGAKTVFWNGPMGVFEFDQFAAGTNAVAAAVGSLKDQA 363
Query: 353 FSVLGGGHSIASIQKYG-IEGITHISTGGGAMLTFFAGEELPVLRAL 398
++V+GGG S+++I K G + I HISTGGGA L G+ELP + A+
Sbjct: 364 YTVVGGGDSVSAINKSGKADQIDHISTGGGASLELLEGKELPGVVAM 410
>sp|P11665|PGK_ECOLI PHOSPHOGLYCERATE KINASE >gi|66907|pir||TVECG phosphoglycerate
kinase (EC 2.7.2.3) - Escherichia coli
>gi|41422|emb|CAA32604.1| (X14436) phosphoglycerate
kinase (AA 1-387) [Escherichia coli]
>gi|882455|gb|AAA69093.1| (U28377) phosphoglycerate
kinase [Escherichia coli] >gi|1789294|gb|AAC75963.1|
(AE000376) phosphoglycerate kinase [Escherichia coli
K12]
Length = 387
Score = 219 bits (552), Expect = 5e-56
Identities = 144/406 (35%), Positives = 221/406 (53%), Gaps = 33/406 (8%)
Query: 1 MFRLGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGK 60
+ ++ D + K VF+R DLN P+KDGK+ SDAR RA LPTI+ L+ GA+V+V +H G+
Sbjct: 3 VIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARIRASLPTIELALKQGAKVMVTSHLGR 62
Query: 61 PYSEDYATTEEHARI-----LSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRF 115
P +Y EE + + L + L+ V V+D ++ GE+ +LEN+RF
Sbjct: 63 PTEGEY--NEEFSLLPVVNYLKDKLSNPVRLVKDYLDGV------DVAEGELVVLENVRF 114
Query: 116 SAEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIM-GFLM 174
+ E K+ KK + + D V DAF AHR+Q S G + + G L+
Sbjct: 115 NKGEKKDDET-------LSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFADVACAGPLL 167
Query: 175 EREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAK 234
E++AL KA P V ++GG+KV L V +++ + AD ++ GG +AN F A+
Sbjct: 168 AAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSK--IADQLIVGGGIANTFIAAQ 225
Query: 235 GFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRE 294
G D+G+ E +LV A+++L + P D + + L +
Sbjct: 226 GHDVGKSLYE-------ADLVDEAKRLLTTCN--IPVPSDVRVATEFSETAPATLKSVND 276
Query: 295 LLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFS 354
+ D QI+DIG + ++ +I+ AK ++ NGP+GVFE F GT V AIA+SEAFS
Sbjct: 277 VKADEQILDIGDASAQELAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIADSEAFS 336
Query: 355 VLGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRALQ 399
+ GGG ++A+I +GI + I++ISTGGGA L F G+ LP + L+
Sbjct: 337 IAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLE 382
>gb|AAF45020.1|AF108451_1 (AF108451) phosphoglycerate kinase precursor [Phaeodactylum
tricornutum]
Length = 441
Score = 219 bits (551), Expect = 6e-56
Identities = 141/403 (34%), Positives = 211/403 (51%), Gaps = 21/403 (5%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS 63
L D K V +R D+N P+ KI D R R+ +PTI+YL GA V V +H G+P
Sbjct: 49 LSDAELKGKKVLVRCDVNVPLDGKKITDDTRIRSSIPTIEYLKNKGAIVSVCSHLGRPKD 108
Query: 64 --EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVK 121
ED + A + LL Q V D G + + + K G++ MLEN RF EE K
Sbjct: 109 GPEDKFSLGPCAERMGELLGQTVTLAPDCIGEEVAKIVNDAKEGDVIMLENTRFYKEETK 168
Query: 122 NKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIEA 180
N P FV+KL+ D VNDAF AHR+ S G + +KP + GFL+ +E+E
Sbjct: 169 NDPE-------FVEKLAAPFDLYVNDAFGTAHRAHASTEGVTKFLKPSVGGFLLAKELEY 221
Query: 181 LMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGR 240
L A + + P ++GG+KV + V E +L + D ++ GG + F AKGF++G
Sbjct: 222 LDGAISNGKKPMAAIVGGSKVSSKITVLEALLDK--CDKVIIGGGMVFTFLKAKGFNVGT 279
Query: 241 KNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQ 300
+E E++ AEK+ E + P+D I K D E + E+ + +
Sbjct: 280 SLVEDDFVDTAKEVLAKAEKLGKE----ILLPIDIVIADKFDAEAETKVVSAEEIPDGWM 335
Query: 301 IMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIA----ESEAFSVL 356
+D G T + ++ + K ++ NGPMGVFE E+FA GT ++ +A + A +++
Sbjct: 336 GLDNGPETTAQQKEALSDCKTIIMNGPMGVFEFEKFAKGTFDLVNILADLSKDKGAITII 395
Query: 357 GGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
GGG S+A+ ++ G G ++HISTGGGA L G+ LP + AL
Sbjct: 396 GGGDSVAATEQSGRAGDMSHISTGGGASLELLEGKVLPGVAAL 438
>sp|P12783|PGKY_WHEAT PHOSPHOGLYCERATE KINASE, CYTOSOLIC >gi|66911|pir||TVWTGY
phosphoglycerate kinase (EC 2.7.2.3), cytosolic - wheat
>gi|21835|emb|CAA33302.1| (X15232) phosphoglycerate
kinase (AA 1 - 401) [Triticum aestivum]
Length = 401
Score = 218 bits (549), Expect = 1e-55
Identities = 142/407 (34%), Positives = 222/407 (53%), Gaps = 30/407 (7%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDG-KIISDARFRAVLPTIKYLLENGARVVVGTHQGKP- 61
LG+ + K VF+R DLN P+ D KI D R RA +PTIKYLLE GA+V++ +H G+P
Sbjct: 10 LGEADLKGKKVFVRADLNVPLDDAQKITDDTRIRASIPTIKYLLEKGAKVILASHLGRPK 69
Query: 62 -YSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV 120
+ ++ AR LS LL V D G + L G + +LEN+RF EE
Sbjct: 70 GVTPKFSLKPLVAR-LSELLGLEVVMAPDCIGEEVEKLAAALPDGGVLLLENVRFYKEEE 128
Query: 121 KNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIE 179
KN P F KKL+ V D VNDAF AHR+ S G + ++P + GFLM++E++
Sbjct: 129 KNDP-------EFAKKLASVADLYVNDAFGTAHRAHASTEGVTKFLRPSVAGFLMQKELD 181
Query: 180 ALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLG 239
L+ A + + P ++GG+KV + V E++L + D+++ GG + F A+G +G
Sbjct: 182 YLVGAVANPKKPFAAIVGGSKVSSKIGVIESLLAK--VDILILGGGMIFTFYKAQGLAVG 239
Query: 240 RKNIEFMKKKGLLELVKHAE----KILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKREL 295
+ +E K + L++ A+ K+L P D + K + + +
Sbjct: 240 KSLVEEDKLELATSLIETAKSKGVKLL--------LPTDVVVADKFAADAESKIVPATAI 291
Query: 296 LNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAE---SEA 352
+ + +D+G +I+ + + + K V+ NGPMGVFE E+FA GT + K +AE
Sbjct: 292 PDGWMGLDVGPDSIKTFAEALDTTKTVIWNGPMGVFEFEKFAAGTDAIAKQLAELTGKGV 351
Query: 353 FSVLGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRAL 398
+++GGG S+A+++K G+ + ++HISTGGGA L G+ LP + AL
Sbjct: 352 TTIIGGGDSVAAVEKAGLADKMSHISTGGGASLELLEGKPLPGVLAL 398
>sp|Q9Z5C4|PGK_STAAU PHOSPHOGLYCERATE KINASE >gi|4490614|emb|CAB38646.1| (AJ133520)
phosphoglycerate kinase [Staphylococcus aureus]
Length = 396
Score = 217 bits (548), Expect = 1e-55
Identities = 145/403 (35%), Positives = 213/403 (51%), Gaps = 23/403 (5%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS 63
+ D + K V +R D N P+KDG+I +D R LPTI+Y++E G ++V+ +H GK
Sbjct: 6 VSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKE 65
Query: 64 ED---YATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV 120
E T A LS L++ V +V + G I++LK G++ ++EN R+ +
Sbjct: 66 ESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDG 125
Query: 121 KNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEA 180
K + + E K + + D VNDAF AHR S VG + GFLM++EI+
Sbjct: 126 KKESKNDPE---LGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKF 182
Query: 181 LMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGR 240
+ P V +LGGAKV D + V +N++ AD I+ GG +A F A+G ++G
Sbjct: 183 IGGVVNDPHKPVVAILGGAKVSDKINVIKNLV--NIADKIIIGGGMAYTFLKAQGKEIGI 240
Query: 241 KNIEFMK---KKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLN 297
+E K K LLE KH +KI+ PVD + + + + +
Sbjct: 241 SLLEEDKIDFAKDLLE--KHGDKIV--------LPVDTKVAKEFSNDAKITVVPSDSIPA 290
Query: 298 DYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAE-SEAFSVL 356
D + MDIG T++ + D + A VV NGPMGVFE FA GT+ V KAIA +A +++
Sbjct: 291 DQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITII 350
Query: 357 GGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
GGG S A+ G E THISTGGGA L + G+ELP ++A+
Sbjct: 351 GGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAI 393
>sp|P50318|PGKH_ARATH PHOSPHOGLYCERATE KINASE, CHLOROPLAST >gi|2129669|pir||S71368
phosphoglycerate kinase (EC 2.7.2.3) OBP44 - Arabidopsis
thaliana (fragment) >gi|1022805|gb|AAB60303.1| (U37701)
phosphoglycerate kinase [Arabidopsis thaliana]
Length = 399
Score = 217 bits (546), Expect = 2e-55
Identities = 142/396 (35%), Positives = 219/396 (54%), Gaps = 24/396 (6%)
Query: 12 KVVFLRVDLNSPMKDGKIISD-ARFRAVLPTIKYLLENGARVVVGTHQGKP--YSEDYAT 68
K VF+R DLN P+ D + I+D R RA +PTIKYL+ENGA+V++ TH G+P + ++
Sbjct: 11 KKVFVRADLNVPLDDNQTITDDTRIRAAIPTIKYLIENGAKVILSTHLGRPKGVTPKFSL 70
Query: 69 TEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPIEEC 128
R LS LL V +D G + L G + +LEN+RF EE KN P
Sbjct: 71 APLVPR-LSELLGIEVTKADDCIGPEVESLVASLPEGGVLLLENVRFYKEEEKNDP---- 125
Query: 129 EKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIEALMKAYYS 187
F KKL+ + D VNDAF AHR+ S G + +KP + GFL+++E++ L+ A +
Sbjct: 126 ---EFAKKLASLADLYVNDAFGTAHRAHASTEGVTKFLKPSVAGFLLQKELDYLVGAVSN 182
Query: 188 KESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNIEFMK 247
+ P ++GG+KV + V E++L + D++L GG + F A+G +G +E K
Sbjct: 183 PKRPFAAIVGGSKVSSKIGVIESLLEK--CDILLLGGGMIFTFYKAQGLSVGSSLVEEDK 240
Query: 248 KKGLLELVKHAE-KILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIMDIGS 306
+ EL+ A+ K + P T V A + D + + E + + +DIG
Sbjct: 241 LELATELLAKAKAKGVSLLLP---TDVVVADKFAPDANSKIVPASGIE--DGWMGLDIGP 295
Query: 307 RTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIA---ESEAFSVLGGGHSIA 363
+I+ + + + + V+ NGPMGVFE E+FA GT + +A E +++GGG S+A
Sbjct: 296 DSIKTFNEALDTTQTVIWNGPMGVFEMEKFAAGTEAIANKLAELSEKGVTTIIGGGDSVA 355
Query: 364 SIQKYGIEGI-THISTGGGAMLTFFAGEELPVLRAL 398
+++K G+ G+ +HISTGGGA L G+ LP + AL
Sbjct: 356 AVEKVGVAGVMSHISTGGGASLELLEGKVLPGVIAL 391
>sp|Q42962|PGKY_TOBAC PHOSPHOGLYCERATE KINASE, CYTOSOLIC >gi|7434547|pir||T03661
phosphoglycerate kinase (EC 2.7.2.3), cytosolic - common
tobacco >gi|1161602|emb|CAA88840.1| (Z48976)
phosphoglycerate kinase (PGK) [Nicotiana tabacum]
Length = 401
Score = 217 bits (546), Expect = 2e-55
Identities = 143/404 (35%), Positives = 224/404 (55%), Gaps = 24/404 (5%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDG-KIISDARFRAVLPTIKYLLENGARVVVGTHQGKP- 61
L + + K VF+RVDLN P+ + I D R RA +PTIKYL+++G+ V++ +H G+P
Sbjct: 10 LKEADLKGKRVFVRVDLNVPLDENFNITDDTRIRAAVPTIKYLMQHGSHVILASHLGRPK 69
Query: 62 -YSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV 120
+ Y+ R LS LL V+ D G + + E+ G + +LEN+RF EE
Sbjct: 70 GVTPKYSLKPLVPR-LSELLGVEVKIANDSIGPEVEKLVAEIPEGGVLLLENVRFYKEEE 128
Query: 121 KNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIE 179
KN+P F KKL+ + D VNDAF AHR+ S G A+ +KP + GFLM++E++
Sbjct: 129 KNEPE-------FAKKLASLADLYVNDAFGTAHRAHASTEGVAKYLKPAVAGFLMQKELD 181
Query: 180 ALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLG 239
L+ A + + P ++GG+KV + V E++L + DV+L GG + F A+G+ +G
Sbjct: 182 YLVGAVANPQKPFAAIVGGSKVSSKIGVIESLLEK--VDVLLLGGGMIFTFYKAQGYAVG 239
Query: 240 RKNIEFMKKKGLLELVKHAE-KILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLND 298
+E K L++ A+ K + P T V A + D + + E+ +
Sbjct: 240 SSLVEEDKLDLATSLMEKAKAKGVSLLLP---TDVVIADKFAADANSKVVPAS--EIPDG 294
Query: 299 YQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAE---SEAFSV 355
+ +DIG I+ + + K V+ NGPMGVFE ++FA GT + K +AE ++
Sbjct: 295 WMGLDIGPDAIKSFGSALDTTKTVIWNGPMGVFEFDKFAAGTEAIAKKLAELSGKGVTTI 354
Query: 356 LGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRAL 398
+GGG S+A+++K G+ E ++HISTGGGA L G+ LP + AL
Sbjct: 355 IGGGDSVAAVEKVGLAEKMSHISTGGGASLELLEGKPLPGVLAL 398
>sp|O32756|PGK_LACDE PHOSPHOGLYCERATE KINASE >gi|7434542|pir||T09634 phosphoglycerate
kinase (EC 2.7.2.3) - Lactobacillus delbrueckii
>gi|2624192|emb|CAA04015.1| (AJ000339) phosphoglycerate
kinase [Lactobacillus delbrueckii]
Length = 403
Score = 217 bits (546), Expect = 2e-55
Identities = 145/402 (36%), Positives = 224/402 (55%), Gaps = 24/402 (5%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS 63
+ D + +K V +RVD N P+KDG I D R A LPTIKY++ENG + ++ +H G+ S
Sbjct: 6 VSDVDVKDKKVLVRVDFNVPIKDGVIGDDNRIVAALPTIKYIIENGGKAILLSHLGRIKS 65
Query: 64 ED---YATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV 120
++ + A+ L LL + V +V G+ + I +K G++ +LEN RF +
Sbjct: 66 DEDKKSLSLAPVAKRLGELLEKPVTFVPSNEGKEVEDAINNMKDGDVVVLENTRFQDIDN 125
Query: 121 KNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARI-----KPMIMGFLME 175
E + + + D VNDAF AHRS S VG A KP GFL+E
Sbjct: 126 DFGKRESKNDPKLGEYWASLGDVFVNDAFGTAHRSHASNVGIATAMKAAGKPAAAGFLLE 185
Query: 176 REIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKG 235
+EI+ L A + P V +LGGAKV D + V N++ + AD I+ GG +A F A+G
Sbjct: 186 KEIKFLGNAVANPVHPFVTILGGAKVSDKIGVITNLIPK--ADHIIIGGGMAYTFLKAQG 243
Query: 236 FDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVD--FAIDYKGDREEIYLLSEKR 293
++G+ +E K V+ A+++L++ + P+D A ++ D + +
Sbjct: 244 HNIGKSLVEDDK-------VEFAKELLEKAGDKLVLPIDNVAATEFNNDAASEVV---GQ 293
Query: 294 ELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAE-SEA 352
++ ++ +DIG +TIE ++ + AK VV NGPMGVFE FA GT+EV +A+A+ +A
Sbjct: 294 DIPDNEMGLDIGPKTIELFKKTLEGAKTVVWNGPMGVFEMPNFAKGTLEVGRALADLPDA 353
Query: 353 FSVLGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELP 393
+++GGG S A+ ++ GI +THISTGGGA L + G+ELP
Sbjct: 354 TTIVGGGDSTAAAKQLGIAPKLTHISTGGGASLEYLEGKELP 395
>gb|AAF70258.1|AF247558_1 (AF247558) phosphoglycerate kinase [Arabidopsis thaliana]
>gi|9230131|dbj|BAB00848.1| (AB024033) phosphoglycerate
kinase [Arabidopsis thaliana]
Length = 481
Score = 217 bits (546), Expect = 2e-55
Identities = 142/396 (35%), Positives = 219/396 (54%), Gaps = 24/396 (6%)
Query: 12 KVVFLRVDLNSPMKDGKIISD-ARFRAVLPTIKYLLENGARVVVGTHQGKP--YSEDYAT 68
K VF+R DLN P+ D + I+D R RA +PTIKYL+ENGA+V++ TH G+P + ++
Sbjct: 93 KKVFVRADLNVPLDDNQTITDDTRIRAAIPTIKYLIENGAKVILSTHLGRPKGVTPKFSL 152
Query: 69 TEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPIEEC 128
R LS LL V +D G + L G + +LEN+RF EE KN P
Sbjct: 153 APLVPR-LSELLGIEVTKADDCIGPEVESLVASLPEGGVLLLENVRFYKEEEKNDP---- 207
Query: 129 EKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIEALMKAYYS 187
F KKL+ + D VNDAF AHR+ S G + +KP + GFL+++E++ L+ A +
Sbjct: 208 ---EFAKKLASLADLYVNDAFGTAHRAHASTEGVTKFLKPSVAGFLLQKELDYLVGAVSN 264
Query: 188 KESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNIEFMK 247
+ P ++GG+KV + V E++L + D++L GG + F A+G +G +E K
Sbjct: 265 PKRPFAAIVGGSKVSSKIGVIESLLEK--CDILLLGGGMIFTFYKAQGLSVGSSLVEEDK 322
Query: 248 KKGLLELVKHAE-KILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIMDIGS 306
+ EL+ A+ K + P T V A + D + + E + + +DIG
Sbjct: 323 LELATELLAKAKAKGVSLLLP---TDVVVADKFAPDANSKIVPASGIE--DGWMGLDIGP 377
Query: 307 RTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIA---ESEAFSVLGGGHSIA 363
+I+ + + + + V+ NGPMGVFE E+FA GT + +A E +++GGG S+A
Sbjct: 378 DSIKTFNEALDTTQTVIWNGPMGVFEMEKFAAGTEAIANKLAELSEKGVTTIIGGGDSVA 437
Query: 364 SIQKYGIEGI-THISTGGGAMLTFFAGEELPVLRAL 398
+++K G+ G+ +HISTGGGA L G+ LP + AL
Sbjct: 438 AVEKVGVAGVMSHISTGGGASLELLEGKVLPGVIAL 473
>pir||F83577 phosphoglycerate kinase PA0552 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9946420|gb|AAG03941.1|AE004491_8
(AE004491) phosphoglycerate kinase [Pseudomonas
aeruginosa]
Length = 387
Score = 217 bits (546), Expect = 2e-55
Identities = 140/404 (34%), Positives = 219/404 (53%), Gaps = 29/404 (7%)
Query: 1 MFRLGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGK 60
+ ++ D + K V +R DLN P+KDG++ SDAR +A LPT+K LE GA V+V +H G+
Sbjct: 3 VLKMTDLDLKGKRVLIREDLNVPVKDGQVQSDARIKAALPTLKLALEKGAAVMVCSHLGR 62
Query: 61 PYSEDYA---TTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSA 117
P +++ + + A LS L + V + D E+K G++ + EN+RF+
Sbjct: 63 PTEGEFSAENSLKPVAEYLSKALGREVPLLADYLDGV------EVKAGDLVLFENVRFNK 116
Query: 118 EEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARI-KPMIMGFLMER 176
E KN +K + + D V DAF AHR++ S G AR K G L+
Sbjct: 117 GEKKNADE-------LAQKYAALCDVFVMDAFGTAHRAEGSTHGVARFAKVAAAGPLLAA 169
Query: 177 EIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGF 236
E++AL KA + P ++ G+KV L V ++ G D ++ GG +AN F A G
Sbjct: 170 ELDALGKALGNPARPMAAIVAGSKVSTKLDVLNSLA--GICDQLIVGGGIANTFLAAAGH 227
Query: 237 DLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELL 296
+G+ E +LV+ A+ I + V PVD + + + + E+
Sbjct: 228 KVGKSLYE-------ADLVETAKAIAAKVK--VPLPVDVVVAKEFAESAVATVKAIAEVA 278
Query: 297 NDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVL 356
+D I+DIG +T ++ +++ +K ++ NGP+GVFE ++F GT + AIA+S AFS+
Sbjct: 279 DDDMILDIGPQTAAQFAELLKTSKTILWNGPVGVFEFDQFGEGTRTLANAIADSAAFSIA 338
Query: 357 GGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRALQ 399
GGG ++A+I KYGI E I++ISTGGGA L F G+ LP + L+
Sbjct: 339 GGGDTLAAIDKYGIAERISYISTGGGAFLEFVEGKVLPAVEILE 382
>gb|AAF85975.1|AF275639_1 (AF275639) cytosolic phosphoglycerate kinase [Pisum sativum]
Length = 401
Score = 216 bits (545), Expect = 3e-55
Identities = 141/404 (34%), Positives = 224/404 (54%), Gaps = 24/404 (5%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDG-KIISDARFRAVLPTIKYLLENGARVVVGTHQGKP- 61
L + + K VF+RVDLN P+ D I D R RA +PTIKYL GA+V++ +H G+P
Sbjct: 10 LKEADLKGKRVFVRVDLNVPLDDNLNITDDTRIRAAIPTIKYLTGYGAKVILSSHLGRPK 69
Query: 62 -YSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV 120
+ Y+ R LS LL V D G + + ++ G + +LEN+RF EE
Sbjct: 70 GVTPKYSLKPLVPR-LSELLGSEVTIAGDSIGEEVEKLVAQIPEGGVLLLENVRFHKEEE 128
Query: 121 KNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIE 179
KN P F KKL+ + D VNDAF AHR+ S G A+ +KP + GFLM++E++
Sbjct: 129 KNDPE-------FAKKLASLADLYVNDAFGTAHRAHASTEGVAKYLKPSVAGFLMQKELD 181
Query: 180 ALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLG 239
L+ A + + P ++GG+KV + V E++L + D++L GG + F A+G+ +G
Sbjct: 182 YLVGAVSNPKKPFAAIVGGSKVSSKIGVIESLLEK--VDILLLGGGMVFTFYKAQGYSVG 239
Query: 240 RKNIEFMKKKGLLELVKHAE-KILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLND 298
+E K L++ A+ K + P T V A + D + + + + +
Sbjct: 240 TSLVEEDKLGLATSLIEKAKAKGVSLLLP---TDVVIADKFSADANDKIVPASS--IPDG 294
Query: 299 YQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAE---SEAFSV 355
+ +DIG +I+ + + + K++ V+ NGPMGVFE ++FA GT + K +AE ++
Sbjct: 295 WMGLDIGPDSIKTFNEALDKSQTVIWNGPMGVFEFDKFAAGTEAIAKKLAEISGKGVTTI 354
Query: 356 LGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRAL 398
+GGG S+A+++K G+ + ++HISTGGGA L G+ LP + AL
Sbjct: 355 IGGGDSVAAVEKAGLADKMSHISTGGGASLELLEGKPLPGVLAL 398
>gb|AAD30221.1|AC007202_3 (AC007202) Is a member of the PF|00162 Phosphoglycerate kinase
family. ESTs gb|N38721, gb|T22178, gb|R90345,
gb|R90715, gb|T21140, gb|T46295, gb|H37082, gb|T46076,
gb|N37132, gb|AA597649, gb|AI100648 and gb|Z48462 come
from this gene. [Arabidopsis tha>
>gi|7839393|gb|AAF70260.1|AF247560_1 (AF247560)
cytosolic phosphoglycerate kinase [Arabidopsis thaliana]
Length = 401
Score = 216 bits (544), Expect = 4e-55
Identities = 144/403 (35%), Positives = 219/403 (53%), Gaps = 22/403 (5%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGK-IISDARFRAVLPTIKYLLENGARVVVGTHQGKP- 61
L + + K VF+RVDLN P+ D I D R RA +PTIKYL+ NG+RVV+ +H G+P
Sbjct: 10 LKEADLKGKSVFVRVDLNVPLDDNSNITDDTRIRAAVPTIKYLMGNGSRVVLCSHLGRPK 69
Query: 62 -YSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV 120
+ Y+ R LS LL V D G ++ + L G + +LEN+RF AEE
Sbjct: 70 GVTPKYSLKPLVPR-LSELLGVEVVMANDSIGEEVQKLVAGLPEGGVLLLENVRFYAEEE 128
Query: 121 KNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIE 179
KN P F KKL+ + D VNDAF AHR+ S G A+ +KP + GFLM++E++
Sbjct: 129 KNDPE-------FAKKLAALADVYVNDAFGTAHRAHASTEGVAKFLKPSVAGFLMQKELD 181
Query: 180 ALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLG 239
L+ A + + P ++GG+KV + V E++L D++L GG + F A+G +G
Sbjct: 182 YLVGAVANPKKPFAAIVGGSKVSTKIGVIESLLNT--VDILLLGGGMIFTFYKAQGLSVG 239
Query: 240 RKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDY 299
+E K L+L K + + P D I K + + + + +
Sbjct: 240 SSLVEEDK----LDLAKSLMEKAKAKGVSLLLPTDVVIADKFAPDANSKIVPATAIPDGW 295
Query: 300 QIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAE---SEAFSVL 356
+DIG +I+ + + + K ++ NGPMGVFE ++FA GT V K +AE +++
Sbjct: 296 MGLDIGPDSIKTFSEALDTTKTIIWNGPMGVFEFDKFAAGTEAVAKQLAELSGKGVTTII 355
Query: 357 GGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRAL 398
GGG S+A+++K G+ + ++HISTGGGA L G+ LP + AL
Sbjct: 356 GGGDSVAAVEKVGLADKMSHISTGGGASLELLEGKPLPGVLAL 398
>dbj|BAA33802.1| (AB018411) cytosolic phosphoglycerate kinase 1 [Populus nigra]
Length = 401
Score = 215 bits (543), Expect = 5e-55
Identities = 139/407 (34%), Positives = 221/407 (54%), Gaps = 30/407 (7%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDG-KIISDARFRAVLPTIKYLLENGARVVVGTHQGKP- 61
L + + K VF+RVDLN P+ D I D R RA +PT+KYL+++GARV++ +H G+P
Sbjct: 10 LKETDLKGKRVFVRVDLNVPLDDNFNITDDTRIRAAVPTVKYLMDHGARVILCSHLGRPK 69
Query: 62 -YSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV 120
+ Y+ R LS LL V+ D G + + E+ G + +LEN+RF EE
Sbjct: 70 GVTPKYSLKPLVPR-LSELLGVEVKIANDCIGEEVEKLVAEIPGGGVVLLENVRFHKEEE 128
Query: 121 KNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIE 179
KN P F KKL+ + + VNDAF AHR+ S G A+ +KP + GFLM++E++
Sbjct: 129 KNDPE-------FAKKLASLAEVYVNDAFGTAHRAHASTEGVAKYLKPAVAGFLMQKELD 181
Query: 180 ALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLG 239
L+ A + + P ++GG+KV + V E++L + D + GG + F A+G+ +G
Sbjct: 182 YLVGAVANPKKPFAAIVGGSKVSSKIGVIESLLEK--VDFLFLGGGMIFTFYKAQGYSVG 239
Query: 240 RKNIEFMKKKGLLELVKHAE----KILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKREL 295
+E K L++ A K+L P D + K + + E+
Sbjct: 240 SSLVEEDKLDLATSLIEKARVKGVKLL--------LPTDVVVADKFASDANSKVVPASEI 291
Query: 296 LNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAE---SEA 352
+ + +DIG +I+ + + + K ++ NGPMGVFE E+FA GT + +AE
Sbjct: 292 ADGWMGLDIGPDSIKTFSEALDTTKTIIWNGPMGVFEFEKFAAGTEAIAWKLAELSGKGV 351
Query: 353 FSVLGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRAL 398
+++GGG S+A+++K G+ + ++HISTGGGA L G+ LP + AL
Sbjct: 352 TTIIGGGDSVAAVEKVGLADKMSHISTGGGASLELLEGKPLPGVLAL 398
>gb|AAF45021.1|AF108452_1 (AF108452) phosphoglycerate kinase precursor [Phaeodactylum
tricornutum]
Length = 449
Score = 215 bits (541), Expect = 9e-55
Identities = 142/398 (35%), Positives = 212/398 (52%), Gaps = 26/398 (6%)
Query: 14 VFLRVDLNSPMK--DGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYSEDYATTEE 71
V +RVDLN+P+ D + D R RA++PT K+LLE GA V++ +H G+P E T +
Sbjct: 62 VLVRVDLNAPLATDDVTVTDDTRLRAIVPTTKFLLEQGANVILCSHFGRPKGEIIETGKN 121
Query: 72 H-----ARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPIE 126
+ L LL Q + ++D G + L G++ +LEN RF + E KN P
Sbjct: 122 GRLNPVVKPLEVLLGQTITKLDDCMGPDVEAATKNLGEGKVVLLENTRFYSGETKNDPE- 180
Query: 127 ECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFA-RIKPMIMGFLMEREIEALMKAY 185
L K+ DY V DAF AHR+ S G +K G LME+E++ L A
Sbjct: 181 ------LAAGLGKLADYFVMDAFGTAHRAHSSTAGVTTHMKFNAAGKLMEKELQYLQGAV 234
Query: 186 YSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNIEF 245
+ P + ++GGAKV + V E++L + DVIL GG + F A G+D+G +E
Sbjct: 235 EEPKRPMMAIVGGAKVSTKIPVIESLLDK--CDVILIGGGMIFTFYKALGYDIGASLVE- 291
Query: 246 MKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIMDIG 305
++EL K +E + PVD + K D + +++ ++ D+ +DIG
Sbjct: 292 ---DDIVELASSLMKKAEEKGVKLILPVDVVLADKFDNDANSAVAKVTDISGDWMGLDIG 348
Query: 306 SRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEV----FKAIAESEAFSVLGGGHS 361
TI+ +R I +A +V NGPMGVFE FA GT +V +A AE A +++GGG S
Sbjct: 349 PETIDLFRSEIAEANTIVWNGPMGVFEFSNFAAGTNDVAQMLAQATAERGAVTIIGGGDS 408
Query: 362 IASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRAL 398
+A++ K G+ + ++HISTGGGA L G+ LP + AL
Sbjct: 409 VAAVNKAGLGDKVSHISTGGGASLELLEGKVLPGVAAL 446
>sp|P29409|PGKH_SPIOL PHOSPHOGLYCERATE KINASE, CHLOROPLAST PRECURSOR
>gi|21272|emb|CAA48479.1| (X68430) phosphoglycerate
kinase [Spinacia oleracea]
Length = 433
Score = 214 bits (539), Expect = 2e-54
Identities = 138/395 (34%), Positives = 218/395 (54%), Gaps = 22/395 (5%)
Query: 12 KVVFLRVDLNSPMKDGK-IISDARFRAVLPTIKYLLENGARVVVGTHQGKP--YSEDYAT 68
K VF+R DLN P+ D + I D R RA +PTIK+L+ NGA+V++ +H G+P + ++
Sbjct: 45 KKVFVRADLNVPLDDSQNITDDTRIRAAIPTIKHLINNGAKVILSSHLGRPKGVTPKFSL 104
Query: 69 TEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPIEEC 128
R LS LL V +D G + + EL G + +LEN+RF EE KN P
Sbjct: 105 APLVPR-LSELLGLQVVKADDCIGPDVEKLVAELPEGGVLLLENVRFYKEEEKNDPE--- 160
Query: 129 EKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIEALMKAYYS 187
F KKL+ + D VNDAF AHR+ S G + +KP + GFL+++E++ L+ A +
Sbjct: 161 ----FAKKLASLADLYVNDAFGTAHRAHASTEGVTKFLKPSVAGFLLQKELDYLVGAVSN 216
Query: 188 KESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNIEFMK 247
+ P ++GG+KV + V E++L + D++L GG + F A+G +G +E K
Sbjct: 217 PKRPFAAIVGGSKVSSKIGVIESLLEK--CDILLLGGGMIFTFYKAQGMSVGSSLVEEDK 274
Query: 248 KKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIMDIGSR 307
L+ A+ E + P D I K + + + + + +DIG
Sbjct: 275 LDLATSLLAKAK----EKGVSLLLPTDVVIADKFAADADSKIVPASGIPDGWMGLDIGPD 330
Query: 308 TIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFK---AIAESEAFSVLGGGHSIAS 364
+I+ + + + + V+ NGPMGVFE E+FA GT + K I++ A +++GGG S+A+
Sbjct: 331 SIKTFSEALDTTQTVIWNGPMGVFEFEKFAAGTEAIAKKLEEISKKGATTIIGGGDSVAA 390
Query: 365 IQKYGI-EGITHISTGGGAMLTFFAGEELPVLRAL 398
++K G+ E ++HISTGGGA L G++LP + AL
Sbjct: 391 VEKVGVAEAMSHISTGGGASLELLEGKQLPGVLAL 425
>dbj|BAA33801.1| (AB018410) cytosolic phosphoglycerate kinase 1 [Populus nigra]
Length = 401
Score = 214 bits (539), Expect = 2e-54
Identities = 140/407 (34%), Positives = 222/407 (54%), Gaps = 30/407 (7%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDG-KIISDARFRAVLPTIKYLLENGARVVVGTHQGKP- 61
L + + K VF+RVDLN P+ D I D R RA +PTIKYL+ +GARV++ +H G+P
Sbjct: 10 LKEADLKGKSVFVRVDLNVPLDDNFNITDDTRIRAAVPTIKYLMGHGARVILSSHLGRPK 69
Query: 62 -YSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV 120
+ Y+ R LS LL V+ D G + + E+ G + +LEN+RF EE
Sbjct: 70 GVTPKYSLKPLVPR-LSELLGVDVKMANDCIGVEVEKIVAEIPEGGVLLLENVRFYKEEE 128
Query: 121 KNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIE 179
KN P F KKL+ + + VNDAF AHR+ S G A+ +KP + GFLM++E++
Sbjct: 129 KNDPE-------FAKKLASLAEIYVNDAFGTAHRAHASTEGVAKYLKPAVAGFLMQKELD 181
Query: 180 ALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLG 239
L+ A + + P ++GG+KV + V E++L + D++ GG + F A+G +G
Sbjct: 182 YLVGAVANPKKPFAAIVGGSKVSSKIGVIESLLEK--VDLLFLGGGMIYTFYKAQGHSVG 239
Query: 240 RKNIEFMKKKGLLELVKHAE----KILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKREL 295
+E K L++ A+ K+L P D + K + + E+
Sbjct: 240 SSLVEEDKLDLATSLIEKAKVKGVKLL--------LPADVVVADKFAPDANSKVVPASEI 291
Query: 296 LNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAE---SEA 352
+ + +DIG +I+ + + + K ++ NGPMGVFE E+FA GT + + +AE
Sbjct: 292 PDGWMGLDIGPDSIKTFSEALDTTKTIIWNGPMGVFEFEKFAAGTEAIARKLAELSGKGV 351
Query: 353 FSVLGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRAL 398
+++GGG S+A+++K G+ + ++HISTGGGA L G+ LP + AL
Sbjct: 352 TTIIGGGDSVAAVEKAGLADKMSHISTGGGASLELLEGKPLPGVLAL 398
>sp|Q42961|PGKH_TOBAC PHOSPHOGLYCERATE KINASE, CHLOROPLAST PRECURSOR
>gi|7434546|pir||T03660 phosphoglycerate kinase (EC
2.7.2.3) precursor, chloroplast - common tobacco
>gi|1161600|emb|CAA88841.1| (Z48977) phosphoglycerate
kinase [Nicotiana tabacum]
Length = 481
Score = 213 bits (537), Expect = 3e-54
Identities = 137/395 (34%), Positives = 217/395 (54%), Gaps = 22/395 (5%)
Query: 12 KVVFLRVDLNSPMKDGK-IISDARFRAVLPTIKYLLENGARVVVGTHQGKP--YSEDYAT 68
K VF+R DLN P+ D + I D R RA +PTIK+L+ NGA+V++ +H G+P + Y+
Sbjct: 92 KKVFVRADLNVPLDDNQNITDDTRIRAAVPTIKHLMANGAKVILSSHLGRPKGVTPKYSL 151
Query: 69 TEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPIEEC 128
R LS LL V VED G + + L G + +LEN+RF EE KN+P
Sbjct: 152 APLVPR-LSELLGIQVVKVEDCIGPEVEKLVASLPEGGVLLLENVRFYKEEEKNEPE--- 207
Query: 129 EKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIEALMKAYYS 187
F KKL+ + D VNDAF AHR+ S G + +KP + GFL+++E++ L+ A +
Sbjct: 208 ----FAKKLASLADLYVNDAFGTAHRAHASTEGVTKFLKPSVAGFLLQKELDYLVGAVSN 263
Query: 188 KESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNIEFMK 247
+ P ++GG+KV + V E++L + D++L GG + F A+G +G +E K
Sbjct: 264 PKRPFAAIVGGSKVSSKIGVIESLLEK--CDILLLGGGMIFTFYKAQGLSVGSSLVEEDK 321
Query: 248 KKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIMDIGSR 307
+ L++ A+ P D I K + + + + + +DIG
Sbjct: 322 LELATSLLEKAKAKGVSLL----LPSDVVIADKFAPDANSKIVPASAIPDGWMGLDIGPD 377
Query: 308 TIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAE---SEAFSVLGGGHSIAS 364
+++ + D + K V+ NGPMGVFE ++FA+GT + K +A+ +++GGG S+A+
Sbjct: 378 SVKTFNDALDTTKTVIWNGPMGVFEFDKFAVGTEAIAKKLADLSGKGVTTIIGGGDSVAA 437
Query: 365 IQKYGIEGI-THISTGGGAMLTFFAGEELPVLRAL 398
++K G+ + +HISTGGGA L G+ LP + AL
Sbjct: 438 VEKVGVASVMSHISTGGGASLELLEGKVLPGVIAL 472
>gb|AAG29665.1|AC069159_21 (AC069159) phosphoglycerate kinase, putative [Arabidopsis thaliana]
Length = 478
Score = 212 bits (535), Expect = 5e-54
Identities = 141/406 (34%), Positives = 217/406 (52%), Gaps = 25/406 (6%)
Query: 4 LGDFN---YHNKVVFLRVDLNSPMKDGK-IISDARFRAVLPTIKYLLENGARVVVGTHQG 59
+GD N K VF+R DLN P+ D + I D R RA +PTIK+L+ENGA+V++ TH G
Sbjct: 79 VGDLNSVDLKGKKVFVRADLNVPLDDNQNITDDTRIRAAIPTIKFLIENGAKVILSTHLG 138
Query: 60 KP--YSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSA 117
+P + ++ R LS LL V +D G + L G + +LEN+RF
Sbjct: 139 RPKGVTPKFSLAPLVPR-LSELLGIEVVKADDCIGPEVETLVASLPEGGVLLLENVRFYK 197
Query: 118 EEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMER 176
EE KN+P F KKL+ + D VNDAF AHR+ S G + +KP + GFL+++
Sbjct: 198 EEEKNEP-------DFAKKLASLADLYVNDAFGTAHRAHASTEGVTKFLKPSVAGFLLQK 250
Query: 177 EIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGF 236
E++ L+ A + + P ++GG+KV + V E++L + D++L GG + F A+G
Sbjct: 251 ELDYLVGAVSNPKRPFAAIVGGSKVSSKIGVIESLLEK--CDILLLGGGMIFTFYKAQGL 308
Query: 237 DLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELL 296
+G +E K LEL + P D I K + + +
Sbjct: 309 SVGSSLVEEDK----LELATTLLAKAKARGVSLLLPTDVVIADKFAPDANSKIVPASAIP 364
Query: 297 NDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAE---SEAF 353
+ + +DIG +++ + + + + V+ NGPMGVFE E+FA GT V +AE
Sbjct: 365 DGWMGLDIGPDSVKTFNEALDTTQTVIWNGPMGVFEFEKFAKGTEAVANKLAELSKKGVT 424
Query: 354 SVLGGGHSIASIQKYGIEGI-THISTGGGAMLTFFAGEELPVLRAL 398
+++GGG S+A+++K G+ G+ +HISTGGGA L G+ LP + AL
Sbjct: 425 TIIGGGDSVAAVEKVGVAGVMSHISTGGGASLELLEGKVLPGVVAL 470
>pir||S44063 phosphoglycerate kinase (EC 2.7.2.3) - Rhizopus niveus
Length = 416
Score = 212 bits (533), Expect = 8e-54
Identities = 152/414 (36%), Positives = 226/414 (53%), Gaps = 33/414 (7%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGA-RVVVGTHQGKPYSE 64
D + NK V +RVD N PMKDG I ++ R LPT+KY L+NGA V++ +H G+P E
Sbjct: 11 DLDLKNKRVLIRVDFNVPMKDGAITNNNRIVQALPTVKYALDNGASAVILMSHLGRPNGE 70
Query: 65 DYA--TTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE--- 119
A + + A + LL + VE++ D G + Q G++ +LENLRF EE
Sbjct: 71 AVAKYSLKPVAAEVEKLLGKPVEFLNDCVGPDVEKACQSATGGKVILLENLRFHIEEEGS 130
Query: 120 -----VKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLM 174
K K E K F L+ + D VNDAF AHR+ S+VG + GFLM
Sbjct: 131 AKVRWSKVKADAEAVKKFRA-SLTALADIYVNDAFGTAHRAHSSMVG-VDLSQRAAGFLM 188
Query: 175 EREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAK 234
++E+E KA + P + +LGGAKV D +++ EN+L + A +I+ GG+ FT K
Sbjct: 189 QKELEYFAKALENPARPFLAILGGAKVSDKIQLIENMLDKVNA-LIVCGGM---AFTFKK 244
Query: 235 GFD---LGRKNIEFMKKKGLLELVKH-AEKILDEFYPYVRTPVDF--AIDYKGDREEIYL 288
D +G+ + K + LVK AEK + + PVDF A + D Y
Sbjct: 245 TLDNVKIGKSLFDEAGSKLVRNLVKKAAEKNVKLVF-----PVDFVTADKFAPDANTGY- 298
Query: 289 LSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIA 348
++ + ++++ +D G ++ E +R+ I+K+K +V NGP GVFE + FA GT V A+
Sbjct: 299 ATDADGIPDEWEGLDCGKKSSELFREEILKSKTIVWNGPSGVFEFDAFANGTKSVLNAVI 358
Query: 349 ESE---AFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
E+ A +++GGG + + K+G EG ++HISTGGGA L G+ELP + AL
Sbjct: 359 EATKEGATTIIGGGDTATAALKWGAEGKVSHISTGGGASLELLEGKELPGVTAL 412
>sp|P12782|PGKH_WHEAT PHOSPHOGLYCERATE KINASE, CHLOROPLAST PRECURSOR
>gi|66912|pir||TVWTGC phosphoglycerate kinase (EC
2.7.2.3) precursor, chloroplast - wheat
>gi|21833|emb|CAA33303.1| (X15233) phosphoglycerate
kinase (AA 1 - 480) [Triticum aestivum]
>gi|3293043|emb|CAA51931.1| (X73528) phosphoglycerate
kinase [Triticum aestivum]
Length = 480
Score = 211 bits (532), Expect = 1e-53
Identities = 138/407 (33%), Positives = 217/407 (52%), Gaps = 46/407 (11%)
Query: 12 KVVFLRVDLNSPMKDGK-IISDARFRAVLPTIKYLLENGARVVVGTHQGKP--YSEDYAT 68
K V +R DLN P+ D + I D R RA +PTIKYLL NGA+V++ +H G+P + ++
Sbjct: 89 KRVLVRADLNVPLDDNQNITDDTRIRAAIPTIKYLLSNGAKVILTSHLGRPKGVTPKFSL 148
Query: 69 TEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPIEEC 128
R LS LL V+ ED+ G + + +L G + +LEN+RF EE KN P
Sbjct: 149 APLVPR-LSELLGIEVKKAEDVIGPEVEKLVADLANGAVLLLENVRFYKEEEKNDPE--- 204
Query: 129 EKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIEALMKAYYS 187
F KKL+ + D VNDAF AHR+ S G + +KP + GFL+++E++ L A +
Sbjct: 205 ----FAKKLASLADLFVNDAFGTAHRAHASTEGVTKFLKPSVAGFLLQKELDYLDGAVSN 260
Query: 188 KESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNIEF-- 245
+ P ++GG+KV + V E++L + D++L GG + F A+G +G +E
Sbjct: 261 PKRPFAAIVGGSKVSSKIGVIESLLEK--CDILLLGGGMIFTFYKAQGLSVGSSLVEEDK 318
Query: 246 ----------MKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKREL 295
K KG+ L+ I D+F P + A +
Sbjct: 319 LELATSLLAKAKAKGVSLLLPSDVIIADKFAPDANSQTVPA----------------SAI 362
Query: 296 LNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAE---SEA 352
+ + +DIG +++ + D + + ++ NGPMGVFE ++FA+GT + K +AE
Sbjct: 363 PDGWMGLDIGPDSVKTFNDALDTTQTIIWNGPMGVFEFDKFAVGTESIAKKLAELSKKGV 422
Query: 353 FSVLGGGHSIASIQKYGIEGI-THISTGGGAMLTFFAGEELPVLRAL 398
+++GGG S+A+++K G+ + +HISTGGGA L G+ELP + AL
Sbjct: 423 TTIIGGGDSVAAVEKVGVADVMSHISTGGGASLELLEGKELPGVVAL 469
>sp|P29406|PGK2_RHINI PHOSPHOGLYCERATE KINASE 2 >gi|218041|dbj|BAA01020.1| (D10156)
3-phosphoglycerate kinase [Rhizopus niveus]
Length = 417
Score = 211 bits (532), Expect = 1e-53
Identities = 148/410 (36%), Positives = 225/410 (54%), Gaps = 24/410 (5%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGA-RVVVGTHQGKPYSE 64
D + NK V +RVD N PMKDG I ++ R LPT+KY L+NGA V++ +H G+P E
Sbjct: 11 DLDLKNKRVLIRVDFNVPMKDGAITNNNRIVQALPTVKYALDNGASAVILMSHLGRPNGE 70
Query: 65 DYA--TTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE--- 119
A + + A + LL + VE++ D G + Q G++ +LENLRF EE
Sbjct: 71 AVAKYSLKPVAAEVEKLLGKPVEFLNDCVGPDVEKACQSATGGKVILLENLRFHIEEEGS 130
Query: 120 -----VKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLM 174
K K E K F L+ + D VNDAF AHR+ S+VG + GFLM
Sbjct: 131 AKVRWSKVKADAEAVKKFRA-SLTALADIYVNDAFGTAHRAHSSMVG-VDLSQRAAGFLM 188
Query: 175 EREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAK 234
++E+E KA + P + +LGGAKV D +++ EN+L + A +I+ GG+ FT K
Sbjct: 189 QKELEYFAKALENPARPFLAILGGAKVSDKIQLIENMLDKVNA-LIVCGGM---AFTFKK 244
Query: 235 GFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDF--AIDYKGDREEIYLLSEK 292
D ++ + + + +LV++ K E + PVDF A + D Y ++
Sbjct: 245 TLDNVKQIGKSLFDEAGSKLVRNLVKKAAEKNVKLVFPVDFVTADKFAPDANTGY-ATDA 303
Query: 293 RELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESE- 351
+ ++++ +D G ++ E +R+ I+K+K +V NGP GVFE + FA GT V A+ E+
Sbjct: 304 DGIPDEWEGLDCGKKSSELFREEILKSKTIVWNGPSGVFEFDAFANGTKSVLNAVIEATK 363
Query: 352 --AFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
A +++GGG + + K+G EG ++HISTGGGA L G+ELP + AL
Sbjct: 364 EGATTIIGGGDTATAALKWGAEGKVSHISTGGGASLELLEGKELPGVTAL 413
>pir||T07014 phosphoglycerate kinase (EC 2.7.2.3) precursor, chloroplast -
potato >gi|3328122|gb|AAC26785.1| (AF073473)
phosphoglycerate kinase precursor [Solanum tuberosum]
Length = 482
Score = 211 bits (532), Expect = 1e-53
Identities = 137/403 (33%), Positives = 217/403 (52%), Gaps = 22/403 (5%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGK-IISDARFRAVLPTIKYLLENGARVVVGTHQGKP- 61
L + K VF+R DLN P+ D + I D R RA +PTIK+L+ NGA+V++ +H G+P
Sbjct: 85 LSSSDLKGKKVFVRADLNVPLDDAQNITDDTRIRAAIPTIKHLIANGAKVILSSHLGRPK 144
Query: 62 -YSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV 120
+ Y+ R LS LL V +D G + + L G + +LEN+RF EE
Sbjct: 145 GVTPKYSLAPLVPR-LSELLGIQVVKADDCIGPEVEKLVDSLPEGGVLLLENVRFYKEEE 203
Query: 121 KNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIE 179
KN+P F KKL+ + D VNDAF AHR+ S G + +KP + GFL+++E++
Sbjct: 204 KNEPE-------FAKKLASLADLFVNDAFGTAHRAHASTEGVTKFLKPSVAGFLLQKELD 256
Query: 180 ALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLG 239
L+ A + + P ++GG+KV + V E++L + D++L GG + F A+G +G
Sbjct: 257 YLVGAVSTPKRPFAAIVGGSKVSSKIGVIESLLEK--CDILLLGGGMIFTFYKAQGLSVG 314
Query: 240 RKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDY 299
+E K + L++ A+ P D I K + + + + +
Sbjct: 315 SSLVEEDKLELATSLLEKAKAKGVSLL----LPSDVVIADKFAPDANSKIVPASAIPDGW 370
Query: 300 QIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAE---SEAFSVL 356
+DIG +I+ + D + K V+ NGPMGVFE ++FA GT + K +A+ +++
Sbjct: 371 MGLDIGPDSIKTFNDALDTTKTVIWNGPMGVFEFDKFATGTEAIAKKLADLSGKGVTTII 430
Query: 357 GGGHSIASIQKYGIEGI-THISTGGGAMLTFFAGEELPVLRAL 398
GGG S+A+++K G+ + +HISTGGGA L G+ LP + AL
Sbjct: 431 GGGDSVAAVEKVGVASVMSHISTGGGASLELLEGKVLPGVIAL 473
>sp|Q9Z519|PGK_STRCO PHOSPHOGLYCERATE KINASE >gi|7480321|pir||T36019 phosphoglycerate
kinase - Streptomyces coelicolor
>gi|4468682|emb|CAB38136.1| (AL035591) phosphoglycerate
kinase [Streptomyces coelicolor A3(2)]
Length = 403
Score = 210 bits (530), Expect = 2e-53
Identities = 142/398 (35%), Positives = 203/398 (50%), Gaps = 20/398 (5%)
Query: 12 KVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYSED---YAT 68
K VF+R DLN P+ I D R RAV+PT+K L + GARV+V +H G+P ++
Sbjct: 15 KRVFVRADLNVPLDGTTITDDGRIRAVVPTVKALADAGARVIVASHLGRPKGAPDPAFSL 74
Query: 69 TEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPIEEC 128
AR L LL V + ED G A + L G +A++ENLRF+A E ++
Sbjct: 75 APAAAR-LGELLGADVAFAEDTVGSSAEAVVTGLADGGVAVIENLRFNAGETSK---DDA 130
Query: 129 EKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEALMKAYYSK 188
E+ F KL+ + D V D F A HR S+ + P G+L+ E+ L K
Sbjct: 131 ERAAFADKLAGLADVYVGDGFGAVHRKHASVFDLPKRLPHYAGYLIATEVGVLKKLTDEV 190
Query: 189 ESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNIEFMKK 248
+ P V LGGAKV D L V + +L G AD +L GG +A F AKG+++G ++ +
Sbjct: 191 KRPYVVALGGAKVSDKLAVIDQLL--GKADRLLIGGGMAYTFLKAKGYEVGISLLQEDQI 248
Query: 249 KGLLELVKHAEKILDEFYPYVRTPVDFAI-----DYKGDREEIYLLSEKRELLNDYQIMD 303
+ E ++ AEK E PVD + D K + D + +D
Sbjct: 249 PAVKEYIERAEKNGVELV----LPVDVLVAPEFPDLKTKAPANPTTVAADAIPADQEGLD 304
Query: 304 IGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGHSIA 363
IG T + Y + A V NGPMGVFE ++A GT V +A+ ++ F+V+GGG S A
Sbjct: 305 IGPETRKLYASKLADAGTVFWNGPMGVFEHPDYAEGTKAVAQALVDAPGFTVVGGGDSAA 364
Query: 364 SIQKYGIE--GITHISTGGGAMLTFFAGEELPVLRALQ 399
+++ G + HISTGGGA L + G+ LP L AL+
Sbjct: 365 AVRTLGFDENAFGHISTGGGASLEYLEGKTLPGLAALE 402
>sp|P41758|PGKH_CHLRE PHOSPHOGLYCERATE KINASE, CHLOROPLAST PRECURSOR
>gi|7434543|pir||T08041 phosphoglycerate kinase (EC
2.7.2.3) precursor, chloroplast - Chlamydomonas
reinhardtii >gi|642454|gb|AAA70082.1| (U14912)
phosphoglycerate kinase precursor [Chlamydomonas
reinhardtii]
Length = 461
Score = 210 bits (528), Expect = 3e-53
Identities = 139/397 (35%), Positives = 212/397 (53%), Gaps = 24/397 (6%)
Query: 12 KVVFLRVDLNSPMKDGK--IISDARFRAVLPTIKYLLENGARVVVGTHQGKPY---SEDY 66
K VF+R DLN P+ I D R RA +PT+KYLL+NGA+V++ +H G+P + Y
Sbjct: 76 KRVFVRADLNVPLDKATLAITDDTRIRAAVPTLKYLLDNGAKVLLTSHLGRPKGGPEDKY 135
Query: 67 ATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPIE 126
T AR LS LL + V V+D G + + +K GE+ +LEN RF EE KN+P
Sbjct: 136 RLTPVVAR-LSELLGKPVTKVDDCIGPEVEKAVGAMKNGELLLLENCRFYKEEEKNEP-- 192
Query: 127 ECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIEALMKAY 185
F KKL+ D VNDAF AHR+ S G + +KP + GFL+++E++ L A
Sbjct: 193 -----EFAKKLAANADLYVNDAFGTAHRAHASTEGVTKFLKPSVAGFLLQKELDYLDGAV 247
Query: 186 YSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNIEF 245
+ + P V ++GG+KV + V E ++ + D I+ GG + F A+ +G +E
Sbjct: 248 SNPKRPFVAIVGGSKVSSKITVIEALMEK--CDKIIIGGGMIFTFYKARALKVGSSLVED 305
Query: 246 MKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIMDIG 305
K +EL K E++ + P D + K D + + + +DIG
Sbjct: 306 DK----IELAKKLEEMAKAKGVQLLLPTDVVVADKFDANANTQTVPITAIPDGWMGLDIG 361
Query: 306 SRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIA---ESEAFSVLGGGHSI 362
+++ + D + AK VV NGPMGVFE + TV + +A +++GGG S+
Sbjct: 362 PDSVKTFNDALADAKTVVWNGPMGVFEFPQVRQRTVSIANTLAGLTPKGCITIIGGGDSV 421
Query: 363 ASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRAL 398
A++++ G+ E ++HISTGGGA L G+ LP + AL
Sbjct: 422 AAVEQAGVAEKMSHISTGGGASLELLEGKVLPGVAAL 458
>dbj|BAA33803.1| (AB018412) chloroplast phosphoglycerate kinase [Populus nigra]
Length = 481
Score = 208 bits (525), Expect = 7e-53
Identities = 138/407 (33%), Positives = 215/407 (51%), Gaps = 46/407 (11%)
Query: 12 KVVFLRVDLNSPMKDG-KIISDARFRAVLPTIKYLLENGARVVVGTHQGKP--YSEDYAT 68
K VF+R DLN P+ + KI D R RA +PTIKYL+ GA+V++ +H G+P + ++
Sbjct: 93 KKVFVRADLNVPLDENQKITDDTRIRAAVPTIKYLISKGAKVILSSHLGRPKGVTPKFSL 152
Query: 69 TEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPIEEC 128
R LS LL V +D G + + L G + +LEN+RF EE KN+P
Sbjct: 153 APLVPR-LSELLGIQVVKADDCIGPEVEKLVASLPEGGVLLLENVRFYKEEEKNEPE--- 208
Query: 129 EKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIEALMKAYYS 187
F KKL+ + D VNDAF AHR+ S G + +KP + GFL+++E++ L+ A +
Sbjct: 209 ----FAKKLASMADLYVNDAFGTAHRAHASTEGVTKFLKPSVAGFLLQKELDYLVGAVSN 264
Query: 188 KESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGF----------- 236
+ P ++GG+KV + V E++L + D++L GG + F A+G
Sbjct: 265 PKRPFAAIVGGSKVSSKIGVIESLLEK--CDILLLGGGMIFTFYKAQGLAVGSSLVEEDK 322
Query: 237 -DLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKREL 295
DL +E K KG+ L+ I D+F P + A +
Sbjct: 323 LDLATTLLEKAKAKGVSLLLPSDVVIADKFAPDANSKTVPA----------------SAI 366
Query: 296 LNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAE---SEA 352
+ + +DIG +++ + + + + V+ NGPMGVFE E+FA GT + K +AE
Sbjct: 367 PDGWMGLDIGPESVKTFSEALGTTQTVIWNGPMGVFEFEKFANGTEAIAKKLAELSGKGV 426
Query: 353 FSVLGGGHSIASIQKYGIEGI-THISTGGGAMLTFFAGEELPVLRAL 398
+++GGG S+A+++K G+ + +HISTGGGA L G+ELP + AL
Sbjct: 427 TTIIGGGDSVAAVEKVGVADVMSHISTGGGASLELLEGKELPGVLAL 473
>sp|P29405|PGK1_RHINI PHOSPHOGLYCERATE KINASE 1 >gi|1084488|pir||S44062 phosphoglycerate
kinase (EC 2.7.2.3) - Rhizopus niveus
>gi|218039|dbj|BAA01019.1| (D10155) 3-phosphoglycerate
kinase [Rhizopus niveus]
Length = 417
Score = 208 bits (524), Expect = 9e-53
Identities = 148/411 (36%), Positives = 220/411 (53%), Gaps = 26/411 (6%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGA-RVVVGTHQGKPYSE 64
D N +K V +RVD N PMKDG I ++ R LPT+KY L+NGA V++ +H G+P E
Sbjct: 11 DLNLKDKRVLIRVDFNVPMKDGAITNNNRIVQALPTVKYALDNGASAVILMSHLGRPNGE 70
Query: 65 DYA--TTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE--- 119
A + + A + LL + VE++ D G + Q K G++ +LENLRF EE
Sbjct: 71 AVAKYSLKPVAAEVEKLLGKPVEFLNDCVGPDVEKACQSAKDGKVILLENLRFHIEEEGS 130
Query: 120 -----VKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLM 174
K K E K F L+ + D +NDAF AHR+ S+VG + GFLM
Sbjct: 131 AKVDGQKVKADAEAIKKFRA-SLTTLADIYINDAFGTAHRAHSSMVG-VDLSQRAAGFLM 188
Query: 175 EREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAK 234
++E+E KA + P + +LGGAKV D +++ EN+L + A +I+ GG+ FT K
Sbjct: 189 QKELEYFAKALENPSRPFLAILGGAKVSDKIQLIENMLDKVNA-LIICGGM---AFTFKK 244
Query: 235 GFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDF--AIDYKGDREEIYLLSEK 292
D + + G +LV++ K E + PVDF A + D Y ++
Sbjct: 245 TLDNVKIGKSLFDEPG-SKLVQNLVKKAAEKNVKIVFPVDFITADKFAPDASTGY-ATDD 302
Query: 293 RELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAI----A 348
+ + +Q +D G R+ + +R+ I+K+K +V NGP GVFE + F+ GT V A+
Sbjct: 303 DGIPDGWQGLDCGERSNKLFREEILKSKTIVWNGPSGVFEFDAFSSGTKAVLDAVINATK 362
Query: 349 ESEAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
E ++GGG + + K+G EG ++HISTGGGA L G+ELP + AL
Sbjct: 363 EGATTIIIGGGDTATAALKWGAEGQVSHISTGGGASLELLEGKELPGVTAL 413
>pir||S26623 phosphoglycerate kinase (EC 2.7.2.3) - spinach (fragment)
Length = 425
Score = 208 bits (523), Expect = 1e-52
Identities = 134/387 (34%), Positives = 212/387 (54%), Gaps = 22/387 (5%)
Query: 12 KVVFLRVDLNSPMKDGK-IISDARFRAVLPTIKYLLENGARVVVGTHQGKP--YSEDYAT 68
K VF+R DLN P+ D + I D R RA +PTIK+L+ NGA+V++ +H G+P + ++
Sbjct: 45 KKVFVRADLNVPLDDSQNITDDTRIRAAIPTIKHLINNGAKVILSSHLGRPKGVTPKFSL 104
Query: 69 TEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPIEEC 128
R LS LL V +D G + + EL G + +LEN+RF EE KN P
Sbjct: 105 APLVPR-LSELLGLQVVKADDCIGPDVEKLVAELPEGGVLLLENVRFYKEEEKNDPE--- 160
Query: 129 EKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIEALMKAYYS 187
F KKL+ + D VNDAF AHR+ S G + +KP + GFL+++E++ L+ A +
Sbjct: 161 ----FAKKLASLADLYVNDAFGTAHRAHASTEGVTKFLKPSVAGFLLQKELDYLVGAVSN 216
Query: 188 KESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNIEFMK 247
+ P ++GG+KV + V E++L + D++L GG + F A+G +G +E K
Sbjct: 217 PKRPFAAIVGGSKVSSKIGVIESLLEK--CDILLLGGGMIFTFYKAQGMSVGSSLVEEDK 274
Query: 248 KKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIMDIGSR 307
L+ A+ E + P D I K + + + + + +DIG
Sbjct: 275 LDLATSLLAKAK----EKGVSLLLPTDVVIADKFAADADSKIVPASGIPDGWMGLDIGPD 330
Query: 308 TIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFK---AIAESEAFSVLGGGHSIAS 364
+I+ + + + + V+ NGPMGVFE E+FA GT + K I++ A +++GGG S+A+
Sbjct: 331 SIKTFSEALDTTQTVIWNGPMGVFEFEKFAAGTEAIAKKLEEISKKGATTIIGGGDSVAA 390
Query: 365 IQKYGI-EGITHISTGGGAMLTFFAGE 390
++K G+ E ++HISTGGGA L G+
Sbjct: 391 VEKVGVAEAMSHISTGGGASLELLEGQ 417
>gb|AAC63499.1| (AF052407) phosphoglycerate kinase [Trypanoplasma borreli]
Length = 412
Score = 208 bits (523), Expect = 1e-52
Identities = 143/404 (35%), Positives = 215/404 (52%), Gaps = 18/404 (4%)
Query: 4 LGDFNYHNKVVFLRVDLNSPM-KDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPY 62
L D N K VF+RVD N PM K+G I+ R +A LPTI+ ++ +G RV++G+H G+P
Sbjct: 10 LDDINCRGKRVFVRVDYNVPMDKNGMIVDSNRIKATLPTIRKVITDGGRVIIGSHLGRPK 69
Query: 63 SEDYATTEEHARI-LSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVK 121
S + + + +H L L V++ + A +++ LK GE+ +LENLRF E
Sbjct: 70 SSNPSMSLKHLLPKLEELFGCSVQFAPNALA--AHQQVNMLKDGEVLLLENLRFYKGENS 127
Query: 122 NKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIEA 180
E E LS D V DAF AHR+ S+ G R I I G+LMERE+
Sbjct: 128 KNVDERMEMAAI---LSSYTDLFVCDAFGTAHRNTASMTGIPRLIGAGIAGYLMEREVNF 184
Query: 181 LMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGR 240
L + P V V+GG+KV D + + N+ F I+ GG +A F A+G ++G
Sbjct: 185 LSNVMRNPVRPVVAVVGGSKVSDKIGLLGNLCN--FCQTIVIGGAMAFTFLEAQGRNMGS 242
Query: 241 KNIEFMKKK--GLLELVKHAEKILDEFYPY---VRTPVDFAIDYKGDREEIYLLSEKREL 295
++ K G ++L A ++L + + + PVDFA K + L+++ ++
Sbjct: 243 SKVQRTAKGKGGDIDLYSVARQLLQKAKKHNVRLLLPVDFACA-KEFKNVPPLITDTPDI 301
Query: 296 LNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAES-EAFS 354
Y +D+G +TIE +D+I + + + NGP+GVFE +A G+ KAI+ + S
Sbjct: 302 PEGYMGLDVGPKTIEIIKDVIAEGRTAIWNGPLGVFEFSHYAKGSHATAKAISSNINMLS 361
Query: 355 VLGGGHSIASIQKYGIEGITHISTGGGAMLTFFAGEELPVLRAL 398
++GGG + A+ K EGITHISTGGGA L G+ LP L L
Sbjct: 362 IVGGGET-AACAKASKEGITHISTGGGATLELLEGKTLPGLICL 404
>sp|P57525|PGK_BUCAI PHOSPHOGLYCERATE KINASE >gi|10039114|dbj|BAB13148.1| (AP001119)
phosphoglycerate kinase [Buchnera sp. APS]
Length = 390
Score = 208 bits (523), Expect = 1e-52
Identities = 138/403 (34%), Positives = 217/403 (53%), Gaps = 23/403 (5%)
Query: 3 RLGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPY 62
++ + N K + +R DLN P+++G I SDAR A LPTI+ L+ A+V++ +H G+P
Sbjct: 5 KMTELNITEKRILIRSDLNVPIENGIIQSDARILAALPTIELALQKKAKVIIMSHLGRP- 63
Query: 63 SEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKN 122
E Y T + + + + F + I+ L PGEIA+LEN RF+ E+ N
Sbjct: 64 KEGYYTKKYSLFPIFEYFKKKFNNTKIYFSNNFLDGIK-LNPGEIALLENTRFNKGELNN 122
Query: 123 KPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIEAL 181
E+ K K S + D V DAF +AHR Q S G + +K G L+ EI+AL
Sbjct: 123 D--EQLSK-----KYSDLCDIFVMDAFGSAHRMQSSTYGIGKFVKIACAGLLLISEIDAL 175
Query: 182 MKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRK 241
KA + P V ++GG+KV V + + AD I+ GG +AN F LA + +G+
Sbjct: 176 KKALKKPKRPMVAIVGGSKVSTKFNVLNKLSK--IADTIIVGGGIANTF-LAIDYKIGKS 232
Query: 242 NIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQI 301
E + V A+K+ D++ V P+D + + E ++ + D +I
Sbjct: 233 LYE-------PDFVFEAKKLRDKYNIIV--PIDSRVGKNFCKNEQAIIKSPDNIKEDEEI 283
Query: 302 MDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGHS 361
MD G +I+K II +++ ++ NGP+GVFE F GT + K IA S AFS+ GGG +
Sbjct: 284 MDFGDESIKKIISIITQSQTIMWNGPVGVFEFPNFRKGTEMIAKTIANSNAFSIAGGGDT 343
Query: 362 IASIQKYGIE-GITHISTGGGAMLTFFAGEELPVLRALQISYE 403
++ I + I+ I++ISTGGGA L F G++LP ++ L+ +++
Sbjct: 344 LSVIDMFNIKNNISYISTGGGAFLEFIEGKKLPAIQMLEENFK 386
>sp|P07377|PGKB_TRYBB PHOSPHOGLYCERATE KINASE, CYTOSOLIC (B) (ALLELE 2)
>gi|66900|pir||KIUTGC phosphoglycerate kinase (EC
2.7.2.3), cytosolic (allele 2) - Trypanosoma brucei
>gi|10490|emb|CAA29317.1| (X05889) PGK gene B product
(AA 1 - 421) [Trypanosoma brucei]
>gi|10497|emb|CAA27068.1| (X03370) B PGK (cytosolic) (aa
1-421) [Trypanosoma brucei] >gi|224857|prf||1202269A
kinase,cytosolic phosphoglycerate [Trypanosoma brucei]
Length = 421
Score = 207 bits (521), Expect = 2e-52
Identities = 136/419 (32%), Positives = 213/419 (50%), Gaps = 34/419 (8%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS 63
+ + + K V +RVD N P+ DG I +D R R+ LP ++ +L G V+ +H G+P
Sbjct: 9 INECDLKGKKVLIRVDFNVPLDDGNITNDYRIRSALPAVQKVLTEGGSCVLMSHLGRPKG 68
Query: 64 ------------------EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPG 105
E AT + A+ LS LL++ V + D A + + ++ PG
Sbjct: 69 VSMAEGKELGSAGGIPGFEQKATLKPVAKALSELLSRPVTFAPDCLN--AADVVSKMSPG 126
Query: 106 EIAMLENLRFSAEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARI 165
++ +LEN+RF EE K EE E K LS D ++DAF AHR ++ G +I
Sbjct: 127 DVVLLENVRFYKEEGSKKSTEEREA--MAKILSSYGDVYISDAFGTAHRDSATMTGIPKI 184
Query: 166 KPM-IMGFLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGG 224
G+LME+EI K + P V ++GGAKV D +++ +N+L+R D +L GG
Sbjct: 185 LGNGAAGYLMEKEISYFAKVLGNPPRPLVAIVGGAKVSDKIQLLDNMLQR--IDYLLIGG 242
Query: 225 LVANVFTLAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE 284
+A F A+G+ +G E K + L+K AE + + P+D +
Sbjct: 243 AMAYTFLKAQGYSIGISMCEESKLEFARSLLKKAE----DRKVQIILPIDHVCHTEFKAV 298
Query: 285 EIYLLSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVF 344
+ L++E + + + +DIG +TIEKY I K K + NGPMGVFE ++ GT +
Sbjct: 299 DSPLITEDQNIPEGHMALDIGPKTIEKYVQTIGKCKSAIWNGPMGVFEMVPYSKGTFAIA 358
Query: 345 KAIA----ESEAFSVLGGGHSIASIQKYG-IEGITHISTGGGAMLTFFAGEELPVLRAL 398
KA+ E S++GGG S ++ + G + ++H+STGGGA L G+ LP + L
Sbjct: 359 KAMGRGTHEHGLMSIIGGGDSASAAELSGEAKRMSHVSTGGGASLELLEGKTLPGVTVL 417
>emb|CAB95362.1| (AL359782) phosphoglycerate kinase [Trypanosoma brucei]
Length = 440
Score = 206 bits (520), Expect = 3e-52
Identities = 136/419 (32%), Positives = 215/419 (50%), Gaps = 35/419 (8%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS 63
+ + + K V +RVD N P+K+GKI +D R R+ LPT+K +L G V+ +H G+P
Sbjct: 9 INECDLKGKKVLIRVDFNVPVKNGKITNDYRIRSALPTLKKVLTEGGSCVLMSHLGRPKG 68
Query: 64 ------------------EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPG 105
+ AT + A+ LS LL + V + D A + + ++ PG
Sbjct: 69 IPMAQADKIRSTGGVPGFQQKATLKPVAKRLSELLLRPVTFAPDCLN--AADVVSKMSPG 126
Query: 106 EIAMLENLRFSAEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARI 165
++ +LEN+RF EE K E + K L+ D ++DAF AHR ++ G +I
Sbjct: 127 DVVLLENVRFYKEEGSKKAKE---REAMAKILASYGDVYISDAFGTAHRDSATMTGIPKI 183
Query: 166 KPM-IMGFLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGG 224
G+LME+EI K + P V ++GGAKV D +++ +N+L+R D +L GG
Sbjct: 184 LGNGAAGYLMEKEISYFAKVLGNPPRPLVAIVGGAKVSDKIQLLDNMLQR--IDYLLIGG 241
Query: 225 LVANVFTLAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE 284
+A F A+G+ +G+ E K + L+K AE + V P+D +
Sbjct: 242 AMAYTFLKAQGYSIGKSKCEESKLEFARSLLKKAE----DRKVQVILPIDHVCHTEFKAV 297
Query: 285 EIYLLSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVF 344
+ L++E + + + +DIG +TIEKY I K K + NGPMGVFE ++ GT +
Sbjct: 298 DSPLITEDQNIPEGHMALDIGPKTIEKYVQTIGKCKSAIWNGPMGVFEMVPYSKGTFAIA 357
Query: 345 KAIA----ESEAFSVLGGGHSIASIQKYG-IEGITHISTGGGAMLTFFAGEELPVLRAL 398
KA+ E S++GGG S ++ + G + ++H+STGGGA L G+ LP + L
Sbjct: 358 KAMGRGTHEHGLMSIIGGGDSASAAELSGEAKRMSHVSTGGGASLELLEGKTLPGVAVL 416
>pir||TVUTGB phosphoglycerate kinase (EC 2.7.2.3), glycosomal (allele 4) -
Trypanosoma brucei >gi|10495|emb|CAA29321.1| (X05890)
PGK gene C product (AA 1 - 440) [Trypanosoma brucei]
Length = 440
Score = 206 bits (519), Expect = 4e-52
Identities = 135/419 (32%), Positives = 215/419 (51%), Gaps = 35/419 (8%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS 63
+ + + K V +RVD N P+K+GKI +D R R+ LPT+K +L G V+ +H G+P
Sbjct: 9 INECDLKGKKVLIRVDFNVPVKNGKITNDYRIRSALPTLKKVLTEGGSCVLMSHLGRPKG 68
Query: 64 ------------------EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPG 105
+ AT + A+ LS LL + V + D A + + ++ PG
Sbjct: 69 IPMAQADKIRSTGGVPGFQQKATLKPVAKALSELLLRPVTFAPDCLN--AADVVSKMSPG 126
Query: 106 EIAMLENLRFSAEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARI 165
++ +LEN+RF EE K + + K L+ D ++DAF AHR ++ G +I
Sbjct: 127 DVVLLENVRFYKEEGSKKAKD---REAMAKILASYGDVYISDAFGTAHRDSATMTGIPKI 183
Query: 166 KPM-IMGFLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGG 224
G+LME+EI K + P V ++GGAKV D +++ +N+L+R D +L GG
Sbjct: 184 LGNGAAGYLMEKEISYFAKVLGNPPRPLVAIVGGAKVSDKIQLLDNMLQR--IDYLLIGG 241
Query: 225 LVANVFTLAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE 284
+A F A+G+ +G+ E K + L+K AE + V P+D +
Sbjct: 242 AMAYTFLKAQGYSIGKSKCEESKLEFARSLLKKAE----DRKVQVILPIDHVCHTEFKAV 297
Query: 285 EIYLLSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVF 344
+ L++E + + + +DIG +TIEKY I K K + NGPMGVFE ++ GT +
Sbjct: 298 DSPLITEDQNIPEGHMALDIGPKTIEKYVQTIGKCKSAIWNGPMGVFEMVPYSKGTFAIA 357
Query: 345 KAIA----ESEAFSVLGGGHSIASIQKYG-IEGITHISTGGGAMLTFFAGEELPVLRAL 398
KA+ E S++GGG S ++ + G + ++H+STGGGA L G+ LP + L
Sbjct: 358 KAMGRGTHEHGLMSIIGGGDSASAAELSGEAKRMSHVSTGGGASLELLEGKTLPGVTVL 416
>sp|P07378|PGKC_TRYBB PHOSPHOGLYCERATE KINASE, GLYCOSOMAL (C) >gi|66901|pir||KIUTGG
phosphoglycerate kinase (EC 2.7.2.3), glycosomal (allele
2) - Trypanosoma brucei >gi|10491|emb|CAA29318.1|
(X05889) PGK gene C product (AA 1 - 440) [Trypanosoma
brucei] >gi|10498|emb|CAA27069.1| (X03370) C PGK
(glycosomal) (aa 1-440) [Trypanosoma brucei]
>gi|224858|prf||1202269B kinase,glycosomal
phosphoglycerate [Trypanosoma brucei]
Length = 440
Score = 206 bits (519), Expect = 4e-52
Identities = 135/419 (32%), Positives = 215/419 (51%), Gaps = 35/419 (8%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS 63
+ + + K V +RVD N P+K+GKI +D R R+ LPT+K +L G V+ +H G+P
Sbjct: 9 INECDLKGKKVLIRVDFNVPVKNGKITNDYRIRSALPTLKKVLTEGGSCVLMSHLGRPKG 68
Query: 64 ------------------EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPG 105
+ AT + A+ LS LL + V + D A + + ++ PG
Sbjct: 69 IPMAQAGKIRSTGGVPGFQQKATLKPVAKALSELLLRPVTFAPDCLN--AADVVSKMSPG 126
Query: 106 EIAMLENLRFSAEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARI 165
++ +LEN+RF EE K + + K L+ D ++DAF AHR ++ G +I
Sbjct: 127 DVVLLENVRFYKEEGSKKAKD---REAMAKILASYGDVYISDAFGTAHRDSATMTGIPKI 183
Query: 166 KPM-IMGFLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGG 224
G+LME+EI K + P V ++GGAKV D +++ +N+L+R D +L GG
Sbjct: 184 LGNGAAGYLMEKEISYFAKVLGNPPRPLVAIVGGAKVSDKIQLLDNMLQR--IDYLLIGG 241
Query: 225 LVANVFTLAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE 284
+A F A+G+ +G+ E K + L+K AE + V P+D +
Sbjct: 242 AMAYTFLKAQGYSIGKSKCEESKLEFARSLLKKAE----DRKVQVILPIDHVCHTEFKAV 297
Query: 285 EIYLLSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVF 344
+ L++E + + + +DIG +TIEKY I K K + NGPMGVFE ++ GT +
Sbjct: 298 DSPLITEDQNIPEGHMALDIGPKTIEKYVQTIGKCKSAIWNGPMGVFEMVPYSKGTFAIA 357
Query: 345 KAIA----ESEAFSVLGGGHSIASIQKYG-IEGITHISTGGGAMLTFFAGEELPVLRAL 398
KA+ E S++GGG S ++ + G + ++H+STGGGA L G+ LP + L
Sbjct: 358 KAMGRGTHEHGLMSIIGGGDSASAAELSGEAKRMSHVSTGGGASLELLEGKTLPGVTVL 416
>gb|AAA32121.1| (M33775) phosphoglycerate kinase (gPGK; E.C. 2.7.2.3) [Trypanosoma
brucei]
Length = 440
Score = 205 bits (517), Expect = 6e-52
Identities = 135/419 (32%), Positives = 215/419 (51%), Gaps = 35/419 (8%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS 63
+ + + K V +RVD N P+K+GKI +D R R+ LPT+K +L G V+ +H G+P
Sbjct: 9 INECDLKGKKVLIRVDFNVPVKNGKITNDYRIRSALPTLKKVLTEGGSCVLMSHLGRPKG 68
Query: 64 ------------------EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPG 105
+ AT + A+ LS LL + V + D A + + ++ PG
Sbjct: 69 IPMAQADKIRSTGGVPGFQQKATLKPVAKRLSELLLRPVTFAPDCLN--AADVVSKMSPG 126
Query: 106 EIAMLENLRFSAEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARI 165
++ +LEN+RF EE K + + K L+ D ++DAF AHR ++ G +I
Sbjct: 127 DVVLLENVRFYKEEGSKKAKD---REAMAKILASYGDVYISDAFGTAHRDSATMTGIPKI 183
Query: 166 KPM-IMGFLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGG 224
G+LME+EI K + P V ++GGAKV D +++ +N+L+R D +L GG
Sbjct: 184 LGNGAAGYLMEKEISYFAKVLGNPPRPLVAIVGGAKVSDKIQLLDNMLQR--IDYLLIGG 241
Query: 225 LVANVFTLAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE 284
+A F A+G+ +G+ E K + L+K AE + V P+D +
Sbjct: 242 AMAYTFLKAQGYSIGKSKCEESKLEFARSLLKKAE----DRKVQVILPIDHVCHTEFKAV 297
Query: 285 EIYLLSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVF 344
+ L++E + + + +DIG +TIEKY I K K + NGPMGVFE ++ GT +
Sbjct: 298 DSPLITEDQNIPEGHMALDIGPKTIEKYVQTIGKCKSAIWNGPMGVFEMVPYSKGTFAIA 357
Query: 345 KAIA----ESEAFSVLGGGHSIASIQKYG-IEGITHISTGGGAMLTFFAGEELPVLRAL 398
KA+ E S++GGG S ++ + G + ++H+STGGGA L G+ LP + L
Sbjct: 358 KAMGRGTHEHGLMSIIGGGDSASAAELSGEAKRMSHVSTGGGASLELLEGKTLPGVAVL 416
>sp|P74421|PGK_SYNY3 PHOSPHOGLYCERATE KINASE
Length = 401
Score = 205 bits (517), Expect = 6e-52
Identities = 139/394 (35%), Positives = 212/394 (53%), Gaps = 20/394 (5%)
Query: 12 KVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYSE--DYATT 69
K VF+RVD N P+ +G I D R RA LPTIK LL GA+V++G+H G+P + D
Sbjct: 18 KRVFVRVDFNVPLDNGSITDDTRIRAALPTIKDLLSKGAKVILGSHFGRPKGKVVDSMRL 77
Query: 70 EEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPIEECE 129
L LL Q V +D G KI L G +A+LENLRF A EE
Sbjct: 78 TPVGDRLGELLGQPVVKCDDCIGAEVTAKIASLPNGGVALLENLRFHAG-------EEGN 130
Query: 130 KTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIEALMKAYYSK 188
F K L+ D VNDAF AHR+ S G + P + G+L+E+E++ L A +
Sbjct: 131 DAEFAKALAANADLYVNDAFGTAHRAHASTEGVTHFLSPNVAGYLIEKELQFLQGAIEAP 190
Query: 189 ESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNIEFMKK 248
+ P V ++GG+KV + V E +L + D ++ GG + F A+G + G+ +E K
Sbjct: 191 KRPLVAIVGGSKVSSKIGVIETLLDK--CDKLIIGGGMIFTFYKAQGLNTGKSLVEEDKL 248
Query: 249 KGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIMDIGSRT 308
L+ A++ EF + T V A ++ D + + + + + +DIG +
Sbjct: 249 DLAKSLMAKAKEKGVEF--LLPTDVVVADNFAPDANAQTVGVD--AIPDGWMGLDIGPDS 304
Query: 309 IEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAE---SEAFSVLGGGHSIASI 365
++ ++D + V+ NGPMGVFE ++FA+GT + ++AE S +++GGG S+A++
Sbjct: 305 VKTFQDALAGCGTVIWNGPMGVFEFDKFAVGTEAIACSLAELTASGTVTIIGGGDSVAAV 364
Query: 366 QKYGI-EGITHISTGGGAMLTFFAGEELPVLRAL 398
+K G+ E ++HISTGGGA L G+ LP + AL
Sbjct: 365 EKVGVAEKMSHISTGGGASLELLEGKVLPGIAAL 398
>pdb|16PK| Phosphoglycerate Kinase From Trypanosoma Brucei Bisubstrate Analog
>gi|2781023|pdb|13PK|A Chain A, Ternary Complex Of
Phosphoglycerate Kinase From Trypanosoma Brucei
>gi|2781024|pdb|13PK|B Chain B, Ternary Complex Of
Phosphoglycerate Kinase From Trypanosoma Brucei
>gi|2781025|pdb|13PK|C Chain C, Ternary Complex Of
Phosphoglycerate Kinase From Trypanosoma Brucei
>gi|2781026|pdb|13PK|D Chain D, Ternary Complex Of
Phosphoglycerate Kinase From Trypanosoma Brucei
Length = 415
Score = 205 bits (517), Expect = 6e-52
Identities = 135/419 (32%), Positives = 215/419 (51%), Gaps = 35/419 (8%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS 63
+ + + K V +RVD N P+K+GKI +D R R+ LPT+K +L G V+ +H G+P
Sbjct: 5 INECDLKGKKVLIRVDFNVPVKNGKITNDYRIRSALPTLKKVLTEGGSCVLMSHLGRPKG 64
Query: 64 ------------------EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPG 105
+ AT + A+ LS LL + V + D A + + ++ PG
Sbjct: 65 IPMAQAGKIRSTGGVPGFQQKATLKPVAKRLSELLLRPVTFAPDCLN--AADVVSKMSPG 122
Query: 106 EIAMLENLRFSAEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARI 165
++ +LEN+RF EE K + + K L+ D ++DAF AHR ++ G +I
Sbjct: 123 DVVLLENVRFYKEEGSKKAKD---REAMAKILASYGDVYISDAFGTAHRDSATMTGIPKI 179
Query: 166 KPM-IMGFLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGG 224
G+LME+EI K + P V ++GGAKV D +++ +N+L+R D +L GG
Sbjct: 180 LGNGAAGYLMEKEISYFAKVLGNPPRPLVAIVGGAKVSDKIQLLDNMLQR--IDYLLIGG 237
Query: 225 LVANVFTLAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE 284
+A F A+G+ +G+ E K + L+K AE + V P+D +
Sbjct: 238 AMAYTFLKAQGYSIGKSKCEESKLEFARSLLKKAE----DRKVQVILPIDHVCHTEFKAV 293
Query: 285 EIYLLSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVF 344
+ L++E + + + +DIG +TIEKY I K K + NGPMGVFE ++ GT +
Sbjct: 294 DSPLITEDQNIPEGHMALDIGPKTIEKYVQTIGKCKSAIWNGPMGVFEMVPYSKGTFAIA 353
Query: 345 KAIA----ESEAFSVLGGGHSIASIQKYG-IEGITHISTGGGAMLTFFAGEELPVLRAL 398
KA+ E S++GGG S ++ + G + ++H+STGGGA L G+ LP + L
Sbjct: 354 KAMGRGTHEHGLMSIIGGGDSASAAELSGEAKRMSHVSTGGGASLELLEGKTLPGVTVL 412
>pir||B81285 phosphoglycerate kinase (EC 2.7.2.3) Cj1402c [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968831|emb|CAB73826.1| (AL139078) phosphoglycerate
kinase [Campylobacter jejuni]
Length = 400
Score = 205 bits (515), Expect = 1e-51
Identities = 134/404 (33%), Positives = 213/404 (52%), Gaps = 27/404 (6%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDG-KIISDARFRAVLPTIKYLLENGARVVVGTHQGKP--Y 62
D + K VF+R D N P D I D R R+ +PTI+Y L+NG V++ +H G+P
Sbjct: 9 DIDLAKKKVFIRCDFNVPQDDFLNITDDRRIRSAIPTIRYCLDNGCSVILASHLGRPKEI 68
Query: 63 SEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKN 122
S Y+ E A+ L+ LL++ + +D+ G A+ K LK GEI +LENLRF E KN
Sbjct: 69 SSKYSL-EPVAKRLARLLDKEIVMAKDVIGEDAKTKAMNLKAGEILLLENLRFEKGETKN 127
Query: 123 KPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARI---KPMIMGFLMEREIE 179
K+L+ ++ +NDAF HR+ S+ + K GFL+++EI+
Sbjct: 128 DEN-------LAKELASMVQVYINDAFGVCHRAHSSVEAITKFFDEKHKGAGFLLQKEID 180
Query: 180 ALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLG 239
P V V+GG+KV L+ N+L + D ++ GG +A F A G+D+G
Sbjct: 181 FASNLIKHPARPFVAVVGGSKVSGKLQALTNLLPK--VDKLIIGGGMAFTFLKALGYDIG 238
Query: 240 RKNIEFMKKKGLLELVKHAEKILDE---FYPYVRTPVDFAIDYKGDREEIYLLSEKRELL 296
+E EL++ A KIL + + PVD ++ +E+
Sbjct: 239 NSLLEE-------ELLEEANKILTKGKNLGVKIYLPVDVVAAPACSQDVPMKFVPAQEIP 291
Query: 297 NDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVL 356
N + +DIG ++ ++++I A+ + NGPMGVFE ++F+ G++++ I+E A SV+
Sbjct: 292 NGWMGLDIGPASVRLFKEVISDAQTIWWNGPMGVFEIDKFSKGSIKMSHYISEGHATSVV 351
Query: 357 GGGHSIASIQKYG-IEGITHISTGGGAMLTFFAGEELPVLRALQ 399
GGG + + + G + +T ISTGGGA L G+ELP ++AL+
Sbjct: 352 GGGDTADVVARAGDADEMTFISTGGGASLELIEGKELPGVKALR 395
>gb|AAF71544.1|AF256214_1 (AF256214) phosphoglycerate kinase; Pgk [Brucella abortus]
Length = 396
Score = 205 bits (515), Expect = 1e-51
Identities = 137/407 (33%), Positives = 207/407 (50%), Gaps = 21/407 (5%)
Query: 1 MFR-LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQG 59
MFR L D N +K V +RVDLN PM +G++ R ++PTI L GA+V++ H G
Sbjct: 2 MFRTLDDANVQSKRVLVRVDLNVPMANGEVTDLTRIERIVPTIAELSRKGAKVILLAHFG 61
Query: 60 KP--YSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSA 117
+P + D + + + LS +L+ V + ED G A+ + LK G++ +LEN RF
Sbjct: 62 RPKGVASDENSLKHVVKPLSKVLDHSVHFAEDCIGDKAKPAVDALKDGDVLLLENTRFHK 121
Query: 118 EEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMERE 177
E KN P FV+ L+ D VNDAF+AAHR+ S G A + P G M+ E
Sbjct: 122 GEEKNDPE-------FVQALAANGDLYVNDAFSAAHRAHASTEGLANVLPAFAGRAMQAE 174
Query: 178 IEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFD 237
+EAL K + P V ++GGAKV L + N++ + D ++ GG +AN F AKG D
Sbjct: 175 LEALEKGLGNPARPVVAIVGGAKVSTKLDLLSNLIEK--VDALVIGGGMANTFLAAKGLD 232
Query: 238 LGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLN 297
+G+ E E++ AE + PVD + + + + +
Sbjct: 233 VGKSLCEHELASTAREIMAKAETTKCA----IILPVDAVVGWHFAADTPHQTYGVDSVPG 288
Query: 298 DYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIA----ESEAF 353
D I+D G + + I A +V NGP+G FE F TV+V + +A E +
Sbjct: 289 DAMILDAGELSTDLIASAIDDAATLVWNGPLGAFELSPFDTATVKVARHVAKRTKEGKLV 348
Query: 354 SVLGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRALQ 399
SV GGG ++A++ G+ + T+IST GGA L + G+ LP + L+
Sbjct: 349 SVGGGGDTVAALNHAGVADDFTYISTAGGAFLEWMEGKPLPGVDVLK 395
>sp|P09403|PGK_THETH PHOSPHOGLYCERATE KINASE >gi|66909|pir||TVTWG phosphoglycerate
kinase (EC 2.7.2.3) - Thermus aquaticus
>gi|48249|emb|CAA31006.1| (X12464) PGK (AA 1-390)
[Thermus thermophilus]
Length = 390
Score = 204 bits (514), Expect = 1e-51
Identities = 145/407 (35%), Positives = 212/407 (51%), Gaps = 26/407 (6%)
Query: 1 MFRLGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGK 60
M L D + K V +RVD N P++DGK+ + R LPT+++LL GA +V+ +H G+
Sbjct: 1 MRTLLDLDPKGKRVLVRVDYNVPVQDGKVQDETRILESLPTLRHLLAGGASLVLLSHLGR 60
Query: 61 PYSEDYATTEEHARILSNLLNQHVEYVEDIFGRY------AREKIQELKPGEIAMLENLR 114
P D + + L H+ E F + AR + + L+PGE+ +LEN+R
Sbjct: 61 PKGPD---PKYSLAPVGEALRAHLP--EARFAPFPPGSEEARREAEALRPGEVLLLENVR 115
Query: 115 FSAEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLM 174
F E KN P + +++ + V DAF +AHR+ S+VG AR+ P GFLM
Sbjct: 116 FEPGEEKNDPELSA-------RYARLGEAFVLDAFGSAHRAHASVVGVARLLPAYAGFLM 168
Query: 175 EREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAK 234
E+E+ AL + E P VLGGAKV D + V E++L R D +L GG +A F A
Sbjct: 169 EKEVRALSRLLKDPERPYAVVLGGAKVSDKIGVIESLLPR--IDRLLIGGAMAFTFLKAL 226
Query: 235 GFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRE 294
G ++GR +E + +L+ AE + Y P D + + + R
Sbjct: 227 GGEVGRSLVEEDRLDLAKDLLGRAEALGVRVY----LPEDVVAAERIEAGVETRVFPARA 282
Query: 295 LLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESE-AF 353
+ Y +DIG +T E + + A+ V NGPMGVFE F GT+ V +AIA E AF
Sbjct: 283 IPVPYMGLDIGPKTREAFARALEGARTVFWNGPMGVFEVPPFDEGTLAVGQAIAALEGAF 342
Query: 354 SVLGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRALQ 399
+V+GGG S+A++ + G+ E H+STGGGA L F LP L L+
Sbjct: 343 TVVGGGDSVAAVNRLGLKERFGHVSTGGGASLEFLEKGTLPGLEVLE 389
>sp|P46273|PGK_CANAL PHOSPHOGLYCERATE KINASE >gi|799385|gb|AAA66523.1| (U25180)
phosphoglycerate kinase [Candida albicans]
Length = 417
Score = 204 bits (514), Expect = 1e-51
Identities = 137/410 (33%), Positives = 221/410 (53%), Gaps = 24/410 (5%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPYSE 64
D + K VF+RVD N P+ I ++ R A LPTIKY+ E+ + +V+ +H G+P E
Sbjct: 11 DLDVAGKRVFIRVDFNVPLDGKTITNNQRIVAALPTIKYVEEHKPKYIVLASHLGRPNGE 70
Query: 65 --DYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKN 122
D + A L LL Q V ++ D G + ++ K GEI +LENLR+ EE +
Sbjct: 71 RNDKYSLAPVATELEKLLGQKVTFLNDCVGPEVTKAVENAKDGEIFLLENLRYHIEEEGS 130
Query: 123 KPIEECEKTF--------FVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLM 174
++ +K F ++L+ + D +NDAF AHR+ S+VG + GFLM
Sbjct: 131 SKDKDGKKVKADPEAVKKFRQELTSLADVYINDAFGTAHRAHSSMVGL-EVPQRAAGFLM 189
Query: 175 EREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFT-LA 233
+E+E KA + E P + +LGGAKV D +++ +N+L + D+++ GG +A F +
Sbjct: 190 SKELEYFAKALENPERPFLAILGGAKVSDKIQLIDNLLDK--VDMLIVGGGMAFTFKKIL 247
Query: 234 KGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLSEK 292
+G + K + LV+ A+K E PVDF K D++ + ++
Sbjct: 248 NKMPIGDSLFDEAGAKNVEHLVEKAKKNNVELI----LPVDFVTADKFDKDAKTSSATDA 303
Query: 293 RELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAI---AE 349
+ +++ +D G +++E ++ + KAK +V NGP GVFE E+FA GT + A AE
Sbjct: 304 EGIPDNWMGLDCGPKSVELFQQAVAKAKTIVWNGPPGVFEFEKFANGTKSLLDAAVKSAE 363
Query: 350 SEAFSVLGGGHSIASIQKYG-IEGITHISTGGGAMLTFFAGEELPVLRAL 398
+ ++GGG + +KYG +E ++H+STGGGA L G++LP + AL
Sbjct: 364 NGNIVIIGGGDTATVAKKYGVVEKLSHVSTGGGASLELLEGKDLPGVVAL 413
>emb|CAB61570.1| (AJ251129) phosphoglycerate kinase [Pseudomonas sp. 'TAC II 18']
Length = 387
Score = 204 bits (513), Expect = 2e-51
Identities = 137/404 (33%), Positives = 214/404 (52%), Gaps = 29/404 (7%)
Query: 1 MFRLGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGK 60
+ ++ D + K V +R DLN P+KDG + SDAR A LPTIK LE GA V+V +H G+
Sbjct: 3 VLKMTDLDLQGKRVLIREDLNVPVKDGVVTSDARILASLPTIKLALEKGAAVMVCSHLGR 62
Query: 61 PYSEDYA---TTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSA 117
P +++ + + A LS L + V V D ++K G+I + EN+RF+
Sbjct: 63 PTEGEFSAENSLKPVADYLSKALGREVPLVSDYLNGV------DVKAGDIVLFENVRFNK 116
Query: 118 EEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARI-KPMIMGFLMER 176
E KN K+ + + D V DAF AHR++ G A+ K G L+
Sbjct: 117 GEKKNADE-------LAKQYAALCDVFVMDAFGTAHRAEGPTHGVAKFAKVAAAGPLLAA 169
Query: 177 EIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGF 236
E++AL KA + P ++ G+KV L V ++ + D+++ GG +A+ F A G
Sbjct: 170 ELDALGKALGAPAKPMAAIVAGSKVSTKLDVLNSLSQ--ICDLLIVGGGIASTFLAAAGH 227
Query: 237 DLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELL 296
+G+ E +L+ A I + + T V A ++ E L ++
Sbjct: 228 PVGKSLYE-------PDLLDTARAIAAKVNVPLPTDVVVAKEFAESAEATVKLIA--DVA 278
Query: 297 NDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVL 356
D I+DIG +T E + ++ +K ++ NGP+GVFE ++F GT + KAIA+S AFS+
Sbjct: 279 ADDMILDIGPQTAEHFAQLLKTSKTILWNGPVGVFEFDQFGNGTKVLAKAIADSAAFSIA 338
Query: 357 GGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRALQ 399
GGG ++A+I KYG+ + I++ISTGGGA L F G+ LP + L+
Sbjct: 339 GGGDTLAAIDKYGVADQISYISTGGGAFLEFVEGKVLPAVEVLE 382
>sp|Q27683|PGKB_LEIMA PHOSPHOGLYCERATE KINASE, CYTOSOLIC (B) >gi|499641|gb|AAC12658.1|
(L25120) phosphoglycerate kinase [Leishmania major]
Length = 417
Score = 203 bits (512), Expect = 2e-51
Identities = 137/411 (33%), Positives = 212/411 (51%), Gaps = 32/411 (7%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS 63
+ D +K V +RVD N P+K+GKI +D R R+ LPTI+ +L+ G ++ +H G+P
Sbjct: 9 IDDATVRDKKVLIRVDFNVPVKNGKITNDFRIRSALPTIQKVLKEGGSCILMSHLGRPKG 68
Query: 64 ---------------EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIA 108
E+ AT A +S LL Q VE+ D A +LK ++
Sbjct: 69 ARMSDPSPEKGVRGYEEAATLRPVAARISELLGQKVEFAPDCLD--AASYASKLKNADVL 126
Query: 109 MLENLRFSAEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPM 168
+LEN+RF AEE K E E+ K L+ D V+DAF AHR ++ G ++
Sbjct: 127 LLENVRFYAEEGSKK---EEERDAMAKVLASYGDVYVSDAFGTAHRDSATMTGIPKVLGA 183
Query: 169 -IMGFLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVA 227
G+LME+EI + + P V ++GGAKV D +++ +N+L R + ++ GG +A
Sbjct: 184 GYAGYLMEKEINYFSRVLNNPPRPLVAIVGGAKVSDKIQLLDNMLGR--INYLVIGGAMA 241
Query: 228 NVFTLAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIY 287
F A+G +G E K L+L K K E V PVD + + +
Sbjct: 242 YTFQKAQGRKIGISMCEEDK----LDLAKSLLKKAQERNVQVFLPVDHVCNKEFKAADSP 297
Query: 288 LLSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAI 347
L++E ++ + Y +DIG RTI Y ++I + K + NGPMGVFE ++ GT V KA+
Sbjct: 298 LVTESVDVPDGYMALDIGPRTIHMYEEVIGRCKSAIWNGPMGVFEMPCYSKGTFAVAKAM 357
Query: 348 A----ESEAFSVLGGGHSIASIQKYG-IEGITHISTGGGAMLTFFAGEELP 393
++ S++GGG S ++ + G + ++H+STGGGA L G+ LP
Sbjct: 358 GTGTQKNGLMSIIGGGDSASAAELSGEAKNMSHVSTGGGASLELLEGKTLP 408
>sp|P50312|PGKC_LEIMA PHOSPHOGLYCERATE KINASE, GLYCOSOMAL (C) >gi|499643|gb|AAC12659.1|
(L25121) phosphoglycerate kinase [Leishmania major]
Length = 479
Score = 203 bits (512), Expect = 2e-51
Identities = 137/411 (33%), Positives = 212/411 (51%), Gaps = 32/411 (7%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS 63
+ D +K V +RVD N P+K+GKI +D R R+ LPTI+ +L+ G ++ +H G+P
Sbjct: 9 IDDATVRDKKVLIRVDFNVPVKNGKITNDFRIRSALPTIQKVLKEGGSCILMSHLGRPKG 68
Query: 64 ---------------EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIA 108
E+ AT A +S LL Q VE+ D A +LK ++
Sbjct: 69 ARMSDPSPEKGVRGYEEAATLRPVAARISELLGQKVEFAPDCLD--AASYASKLKNADVL 126
Query: 109 MLENLRFSAEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPM 168
+LEN+RF AEE K E E+ K L+ D V+DAF AHR ++ G ++
Sbjct: 127 LLENVRFYAEEGSKK---EEERDAMAKVLASYGDVYVSDAFGTAHRDSATMTGIPKVLGA 183
Query: 169 -IMGFLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVA 227
G+LME+EI + + P V ++GGAKV D +++ +N+L R + ++ GG +A
Sbjct: 184 GYAGYLMEKEINYFSRVLNNPPRPLVAIVGGAKVSDKIQLLDNMLGR--INYLVIGGAMA 241
Query: 228 NVFTLAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIY 287
F A+G +G E K L+L K K E V PVD + + +
Sbjct: 242 YTFQKAQGRKIGISMCEEDK----LDLAKSLLKKAQERNVQVFLPVDHVCNKEFKAADSP 297
Query: 288 LLSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAI 347
L++E ++ + Y +DIG RTI Y ++I + K + NGPMGVFE ++ GT V KA+
Sbjct: 298 LVTESVDVPDGYMALDIGPRTIHMYEEVIGRCKSAIWNGPMGVFEMPCYSKGTFAVAKAM 357
Query: 348 A----ESEAFSVLGGGHSIASIQKYG-IEGITHISTGGGAMLTFFAGEELP 393
++ S++GGG S ++ + G + ++H+STGGGA L G+ LP
Sbjct: 358 GTGTQKNGLMSIIGGGDSASAAELSGEAKNMSHVSTGGGASLELLEGKTLP 408
>sp|P08966|PGKB_CRIFA PHOSPHOGLYCERATE KINASE, CYTOSOLIC (B) >gi|66905|pir||TVCRGC
phosphoglycerate kinase (EC 2.7.2.3), cytosolic -
Crithidia fasciculata >gi|6983|emb|CAA30341.1| (X07458)
PGK B gene (AA 1-417) [Crithidia fasciculata]
Length = 417
Score = 203 bits (510), Expect = 4e-51
Identities = 138/408 (33%), Positives = 211/408 (50%), Gaps = 32/408 (7%)
Query: 12 KVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS-------- 63
K V +RVD N P+K+G+I +D R R+ LPTI+ +L+ G ++ +H G+P
Sbjct: 17 KKVLIRVDFNVPVKNGEITNDFRIRSALPTIQKVLKEGGSCILMSHLGRPKGAKMSDPKP 76
Query: 64 -------EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFS 116
E+ AT A LS LL Q VE+ D A +LK G++ +LEN+RF
Sbjct: 77 AKSVRGYEEAATLRPVAARLSELLGQKVEFAPDCLD--AASYAAKLKGGDVLLLENVRFY 134
Query: 117 AEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPM-IMGFLME 175
AEE K E E+ K L+ D V+DAF AHR + G ++ G+LME
Sbjct: 135 AEEGSKK---EEERDAMAKVLAAYGDVYVSDAFGTAHRDSADMTGIPKVLGAGYAGYLME 191
Query: 176 REIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKG 235
+EI + + P V ++GGAKV D +++ +N+L R + ++ GG +A F A+G
Sbjct: 192 KEINYFAQVLNNPPRPLVAIVGGAKVSDKIQLLDNMLGR--INYLVIGGAMAYTFQKAQG 249
Query: 236 FDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKREL 295
+G E K L+L K K E V PVD + + + L+++ E+
Sbjct: 250 HAIGISMCEEDK----LDLAKSLLKKAQERNVEVLLPVDHVCNKEFQGVDAPLVTKDVEI 305
Query: 296 LNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIA----ESE 351
Y +DIG +TI+ Y D+I K K + NGPMGVFE ++ GT V KA+ ++
Sbjct: 306 PEGYMALDIGPKTIKIYEDVIAKCKSTIWNGPMGVFEMPCYSKGTFAVAKAMGNGTQKNG 365
Query: 352 AFSVLGGGHSIASIQKYG-IEGITHISTGGGAMLTFFAGEELPVLRAL 398
S++GGG + ++ + G + ++H+STGGGA L G+ LP + L
Sbjct: 366 LMSIIGGGDTASAAELSGEAKNMSHVSTGGGASLELLEGKSLPGVTVL 413
>sp|P08967|PGKC_CRIFA PHOSPHOGLYCERATE KINASE, GLYCOSOMAL (C) >gi|66906|pir||TVCRGG
phosphoglycerate kinase (EC 2.7.2.3), glycosomal -
Crithidia fasciculata >gi|6985|emb|CAA30342.1| (X07459)
PGK C gene (AA 1-455) [Crithidia fasciculata]
Length = 455
Score = 203 bits (510), Expect = 4e-51
Identities = 138/408 (33%), Positives = 211/408 (50%), Gaps = 32/408 (7%)
Query: 12 KVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS-------- 63
K V +RVD N P+K+G+I +D R R+ LPTI+ +L+ G ++ +H G+P
Sbjct: 17 KKVLIRVDFNVPVKNGEITNDFRIRSALPTIQKVLKEGGSCILMSHLGRPKGAKMSDPKP 76
Query: 64 -------EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFS 116
E+ AT A LS LL Q VE+ D A +LK G++ +LEN+RF
Sbjct: 77 AKSVRGYEEAATLRPVAARLSELLGQKVEFAPDCLD--AASYAAKLKGGDVLLLENVRFY 134
Query: 117 AEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPM-IMGFLME 175
AEE K E E+ K L+ D V+DAF AHR + G ++ G+LME
Sbjct: 135 AEEGSKK---EEERDAMAKVLAAYGDVYVSDAFGTAHRDSADMTGIPKVLGAGYAGYLME 191
Query: 176 REIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKG 235
+EI + + P V ++GGAKV D +++ +N+L R + ++ GG +A F A+G
Sbjct: 192 KEINYFAQVLNNPPRPLVAIVGGAKVSDKIQLLDNMLGR--INYLVIGGAMAYTFQKAQG 249
Query: 236 FDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKREL 295
+G E K L+L K K E V PVD + + + L+++ E+
Sbjct: 250 HAIGISMCEEDK----LDLAKSLLKKAQERNVEVLLPVDHVCNKEFQGVDAPLVTKDVEI 305
Query: 296 LNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIA----ESE 351
Y +DIG +TI+ Y D+I K K + NGPMGVFE ++ GT V KA+ ++
Sbjct: 306 PEGYMALDIGPKTIKIYEDVIAKCKSTIWNGPMGVFEMPCYSKGTFAVAKAMGNGTQKNG 365
Query: 352 AFSVLGGGHSIASIQKYG-IEGITHISTGGGAMLTFFAGEELPVLRAL 398
S++GGG + ++ + G + ++H+STGGGA L G+ LP + L
Sbjct: 366 LMSIIGGGDTASAAELSGEAKNMSHVSTGGGASLELLEGKSLPGVTVL 413
>sp|P08893|PGKE_TRYBB PHOSPHOGLYCERATE KINASE, CYTOSOLIC (B) (ALLELE 4)
>gi|66903|pir||TVUTG4 phosphoglycerate kinase (EC
2.7.2.3), cytosolic (allele 4) - Trypanosoma brucei
>gi|10494|emb|CAA29320.1| (X05890) PGK gene B product
(AA 1 - 420) [Trypanosoma brucei]
Length = 420
Score = 203 bits (510), Expect = 4e-51
Identities = 137/419 (32%), Positives = 212/419 (49%), Gaps = 35/419 (8%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS 63
+ + + K V +RVD N P+ DG I +D R R+ LP ++ +L G V+ +H G+P
Sbjct: 9 INECDLKGKKVLIRVDFNVPLDDGNITNDYRIRSALPAVQKVLTEGGSCVLMSHLGRPKG 68
Query: 64 ------------------EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPG 105
E AT + A+ LS LL++ V + D A + + ++ PG
Sbjct: 69 VSMAEGKELRSTGGIPGFEQKATLKPVAKALSELLSRPVTFAPDCLN--AADVVSKMSPG 126
Query: 106 EIAMLENLRFSAEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARI 165
++ +LEN+RF EE +K EE E K L+ D ++DAF AHR ++ G +I
Sbjct: 127 DVVLLENVRFYKEE-GSKSTEEREA--MAKILASYGDVYISDAFGTAHRDSATMTGIPKI 183
Query: 166 KPM-IMGFLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGG 224
G+LME+EI K + P V ++GGAKV D +++ +N+L+R D +L GG
Sbjct: 184 LGHGAAGYLMEKEISYFAKVLGNPPRPLVAIVGGAKVSDKIQLLDNMLQR--IDYLLIGG 241
Query: 225 LVANVFTLAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE 284
+A F A+G+ +G E K + L+K AE + V P+D +
Sbjct: 242 AMAYTFLKAQGYSIGISMCEESKLEFARSLLKKAE----DRKVQVILPIDHVCHTEFKAV 297
Query: 285 EIYLLSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVF 344
+ L++E + + + +DIG +TIEKY I K K + NGPMGVFE ++ GT +
Sbjct: 298 DSPLITEDQNIPEGHMALDIGPKTIEKYVQTIGKCKSAIWNGPMGVFEMVPYSKGTFAIA 357
Query: 345 KAIA----ESEAFSVLGGGHSIASIQKYG-IEGITHISTGGGAMLTFFAGEELPVLRAL 398
KA+ E S++GGG S + + G I+H+STGGGA L G+ LP + L
Sbjct: 358 KAMGRGTHEHGLMSIIGGGESAGAAELCGEAARISHVSTGGGASLELLEGKTLPGVTVL 416
>gb|AAA32120.1| (M33775) phosphoglycerate kinase [Trypanosoma brucei]
Length = 420
Score = 203 bits (510), Expect = 4e-51
Identities = 135/419 (32%), Positives = 215/419 (51%), Gaps = 35/419 (8%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS 63
+ + + K V +RVD N P+ DG I +D R R+ LP ++ +L G V+ +H G+P
Sbjct: 9 INECDLKGKKVLIRVDFNVPLDDGNITNDYRIRSALPAVQKVLTEGGSCVLMSHLGRPKG 68
Query: 64 ------------------EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPG 105
E AT + A+ LS LL++ V + D A + + ++ PG
Sbjct: 69 VSMAEGKELRSAGGIPGFEQKATLKPVAKRLSELLSRPVTFAPDCLN--AADVVSKMSPG 126
Query: 106 EIAMLENLRFSAEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARI 165
++ +LEN+RF EE +K EE E K L+ D ++DAF AHR ++ G +I
Sbjct: 127 DVVLLENVRFYKEE-GSKSTEEREA--MAKILASYGDVYISDAFGTAHRDSATMTGIPKI 183
Query: 166 KPM-IMGFLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGG 224
G+LME+EI K + P V ++GGAKV + +++ +N+L+R D +L GG
Sbjct: 184 LGHGAAGYLMEKEISYFAKVLGNPPRPLVAIVGGAKVSEKIQLLDNMLQR--IDYLLIGG 241
Query: 225 LVANVFTLAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE 284
+A F A+G+ +G+ E K + L+K AE + V P+D +
Sbjct: 242 AMAYTFLKAQGYSIGKSKCEESKLEFARSLLKKAE----DRKVQVILPIDHVCHTEFKAV 297
Query: 285 EIYLLSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVF 344
+ L++E + + + +DIG +TIEKY I K K + NGPMGVFE ++ GT +
Sbjct: 298 DSPLITEDQNIPEGHMALDIGPKTIEKYVQTIGKCKSAIWNGPMGVFEMVPYSKGTFAIA 357
Query: 345 KAIA----ESEAFSVLGGGHSIASIQKYG-IEGITHISTGGGAMLTFFAGEELPVLRAL 398
KA+ E S++GGG S ++ + G + ++H+STGGGA L G+ LP + L
Sbjct: 358 KAMGRGTHEHGLMSIIGGGDSASAAELSGEAKRMSHVSTGGGASLELLEGKTLPGVTVL 416
>sp|P09404|PGK_ZYMMO PHOSPHOGLYCERATE KINASE >gi|66908|pir||KIZYG phosphoglycerate
kinase (EC 2.7.2.3) - Zymomonas mobilis
>gi|155604|gb|AAA27699.1| (M19376) phosphoglycerate
kinase [Zymomonas mobilis]
Length = 397
Score = 202 bits (509), Expect = 5e-51
Identities = 133/396 (33%), Positives = 203/396 (50%), Gaps = 22/396 (5%)
Query: 12 KVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYSEDYATTEE 71
K V +R DLN PM ++ D R RA +PT+ L E GA+V++ H G+P +
Sbjct: 15 KRVLVREDLNVPMDGDRVTDDTRLRAAIPTVNELAEKGAKVLILAHFGRPKGQPNPEMSL 74
Query: 72 HARI---LSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPIEEC 128
ARI L+ +L + V ++ DI G A + + L PG +A+LEN RF A E KN P
Sbjct: 75 -ARIKDALAGVLGRPVHFINDIKGEAAAKAVDALNPGAVALLENTRFYAGEEKNDPALAA 133
Query: 129 EKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEALMKAYYSK 188
E ++K+ D+ VNDAF+AAHR+ S G A P G M++E+EAL A
Sbjct: 134 E-------VAKLGDFYVNDAFSAAHRAHVSTEGLAHKLPAFAGRAMQKELEALEAALGKP 186
Query: 189 ESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNIEFMKK 248
P V+GGAKV L V N++ + D ++ GG +AN F A+G D+G+ E K
Sbjct: 187 THPVAAVVGGAKVSTKLDVLTNLVSK--VDHLIIGGGMANTFLAAQGVDVGKSLCEHELK 244
Query: 249 KGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIMDIGSRT 308
+ + AEK + + P D + + ++ D I+D+G +
Sbjct: 245 DTVKGIFAAAEKTGCK----IHLPSDVVVAKEFKANPPIRTIPVSDVAADEMILDVGPKA 300
Query: 309 IEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIA----ESEAFSVLGGGHSIAS 364
+ +++ +K +V NGP+G FE E F TV + K A SV GGG ++A+
Sbjct: 301 VAALTEVLKASKTLVWNGPLGAFEIEPFDKATVALAKEAAALTKAGSLISVAGGGDTVAA 360
Query: 365 IQKYGI-EGITHISTGGGAMLTFFAGEELPVLRALQ 399
+ G+ + + +ST GGA L + G+ELP ++AL+
Sbjct: 361 LNHAGVAKDFSFVSTAGGAFLEWMEGKELPGVKALE 396
>sp|P41759|PGK_SCHMA PHOSPHOGLYCERATE KINASE >gi|556413|gb|AAA93516.1| (L36833)
phosphoglycerate kinase [Schistosoma mansoni]
Length = 416
Score = 202 bits (509), Expect = 5e-51
Identities = 142/424 (33%), Positives = 217/424 (50%), Gaps = 48/424 (11%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKP- 61
+ D + K V +RVD N PMKDGK+ + R A +PTIKY L+ GA+ VV+ +H G+P
Sbjct: 8 ISDVDLKGKRVLIRVDFNVPMKDGKVTNTQRIAAAIPTIKYALDKGAKSVVLMSHLGRPD 67
Query: 62 -YSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV 120
+ D + + +S LL + V ++ D G PG + +LENLRF EE
Sbjct: 68 GHKVDKYSLKPVCPEVSKLLGKEVTFLNDCVGPDVVNACANPAPGSVFLLENLRFHVEEE 127
Query: 121 KNKPIEECEKT--------FFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGF 172
EKT F + L+K+ D VNDAF AHR+ S+VG ++ GF
Sbjct: 128 GKGVSPTGEKTKATADQIKAFSESLTKLGDVYVNDAFGTAHRAHASMVG-CQLPQKACGF 186
Query: 173 LMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGL------- 225
LM +E+ KA + E P + +LGGAKV D +++ N+L + ++I+ GG+
Sbjct: 187 LMNKELTYFAKALENPERPFLAILGGAKVSDKIQLINNMLDK-VNELIIGGGMAYTFLKQ 245
Query: 226 -----VANVFTLAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDF-AIDY 279
+ N A G ++ K +E K K + + PVDF D
Sbjct: 246 IHNMHIGNSLFDAPGAEIVHKVMETAKAKNVA----------------IHLPVDFVTADK 289
Query: 280 KGDREEIYLLSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALG 339
D + + + + + + +DIG +TIE++ +I +AK +V NGPMGVFE ++FA G
Sbjct: 290 FADDANTEIRTIQSGIADGWMGLDIGPKTIEEFSKVISRAKTIVWNGPMGVFEMDKFATG 349
Query: 340 TV----EVFKAIAESEAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPV 394
T EV KA ++ A +++GGG + K+ E ++H+STGGGA L G++LP
Sbjct: 350 TKAAMDEVVKA-TKNGATTIIGGGDTATCCAKWDTEDKVSHVSTGGGASLELLEGKQLPG 408
Query: 395 LRAL 398
+ AL
Sbjct: 409 VVAL 412
>sp|P78018|PGK_MYCPN PHOSPHOGLYCERATE KINASE >gi|2146500|pir||S73738 phosphoglycerate
kinase (EC 2.7.2.3) pgk - Mycoplasma pneumoniae (strain
ATCC 29342) >gi|1674096|gb|AAB96060.1| (AE000040)
phosphoglycerate kinase [Mycoplasma pneumoniae]
Length = 409
Score = 202 bits (509), Expect = 5e-51
Identities = 151/410 (36%), Positives = 215/410 (51%), Gaps = 29/410 (7%)
Query: 7 FNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYSED- 65
F++ K V LR DLN PMKDG I + R A L TIKYLL + ++V+ +H + S D
Sbjct: 10 FDFQGKTVVLRADLNVPMKDGVITDNERILASLDTIKYLLGHNCKIVLLSHLSRVKSLDD 69
Query: 66 ---YATTEEHARILSNLL-NQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRF-----S 116
+ + A L NLL N V + + G + + +L GEI +LEN R+ +
Sbjct: 70 KKGKKSLQPVASALQNLLKNTKVHFCPENTGDKVKVAVNQLPLGEILVLENTRYCDVNEA 129
Query: 117 AEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLME 175
E VK++ E F L D VNDAF AHR S G A+ IK +G LME
Sbjct: 130 GEVVKHESKNNAELAQFWASLG---DIFVNDAFGTAHRRHASNAGIAKYIKNSCIGLLME 186
Query: 176 REIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKG 235
RE+ L + + P V VLGGAKV D L+V N+ + AD IL GG + N F A G
Sbjct: 187 RELINLYRLINNPPKPFVVVLGGAKVSDKLQVVNNLFK--IADHILIGGGMVNTFLKALG 244
Query: 236 FDLGRKNIEFMKKKGLLELVKHAEKILD-EFYPYVRTPVDFAIDYKGDRE---EIYLLSE 291
++G +E +LV+ A++ILD + + VD + E E + +
Sbjct: 245 NEVGTSLVEE-------DLVQTAKQILDSDKDKKIVLGVDQMLHASFKDEPGVECVVAPQ 297
Query: 292 KRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAES- 350
L + +D+GS+T+ + + KAK + NGPMGVFE +A GT+ + KAIA++
Sbjct: 298 WPAELQGFMSLDVGSKTVALFSSYLAKAKTIFWNGPMGVFEFSNYAQGTLAIGKAIAQNQ 357
Query: 351 EAFSVLGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRALQ 399
+AFSV+GGG S A+ ++ I + + ISTGGGA L GEEL + +Q
Sbjct: 358 QAFSVIGGGDSAAAAKQLQIADQFSFISTGGGASLALIGGEELVGISDIQ 407
>sp|P50314|PGK_XANFL PHOSPHOGLYCERATE KINASE >gi|475713|gb|AAA62185.1| (U08462)
phosphoglycerate kinase [Xanthobacter flavus]
Length = 397
Score = 202 bits (508), Expect = 7e-51
Identities = 130/395 (32%), Positives = 205/395 (50%), Gaps = 19/395 (4%)
Query: 11 NKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYSEDYATT- 69
+K V +RVDLN PM+ G++ R +A+LPTI+ + G + V+ H G+P D + +
Sbjct: 15 DKRVLVRVDLNVPMESGRVTDATRLKAILPTIRDITGKGGKAVLLAHLGRPKGRDESQSL 74
Query: 70 EEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPIEECE 129
A+ L L + V + D G A+ + L GE+ +LEN RF A E KN P
Sbjct: 75 APVAKALEGELGRKVAFASDCIGDEAKSAVSRLASGEVIVLENTRFHAGEEKNAPD---- 130
Query: 130 KTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEALMKAYYSKE 189
F++ L+ + D VNDAF+ AHR+ S G AR P G ME EIEAL KA + +
Sbjct: 131 ---FIEALASLGDIYVNDAFSTAHRAHASTEGLARKLPAYAGRSMESEIEALTKALEAPQ 187
Query: 190 SPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNIEFMKKK 249
P + V+GG+KV L++ N++++ D+++ GG +AN F A G +G+ E
Sbjct: 188 RPVLAVVGGSKVSSKLELLGNLVKK--VDILVIGGGMANTFLAALGKKVGKSLCEHDLAN 245
Query: 250 GLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIMDIGSRTI 309
+++K AE E + PVD + + + ++ ++ +D ++D G T+
Sbjct: 246 TARDILKKAEAAGCE----IVLPVDAVVATEFKANAAHRVTSVDDVKDDEMMLDAGPETV 301
Query: 310 EKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAE----SEAFSVLGGGHSIASI 365
+ + AK VV NGP G FE F TV V + + + SV GGG ++A++
Sbjct: 302 GIVKQKLDGAKTVVWNGPFGAFEMTPFDAATVAVARYVGDLTHKGRLLSVAGGGDTVAAL 361
Query: 366 QKYG-IEGITHISTGGGAMLTFFAGEELPVLRALQ 399
G E +++ST GGA L + G+ LP + AL+
Sbjct: 362 NHAGTAERFSYVSTAGGAFLEWLEGKALPGVEALR 396
>emb|CAB95363.1| (AL359782) phosphoglycerate kinase [Trypanosoma brucei]
Length = 420
Score = 201 bits (507), Expect = 9e-51
Identities = 136/419 (32%), Positives = 214/419 (50%), Gaps = 35/419 (8%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS 63
+ + + K V +RVD N P+ DG I +D R R+ LP ++ +L G V+ +H G+P
Sbjct: 9 INECDLKGKKVLIRVDFNVPLDDGNITNDYRIRSALPAVQKVLTEGGSCVLMSHLGRPKG 68
Query: 64 ------------------EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPG 105
E AT + A+ LS LL++ V + D A + + ++ PG
Sbjct: 69 VSMAEGKELRSTGGIPGFEQKATLKPVAKRLSELLSRPVTFAPDCLN--AADVVSKMSPG 126
Query: 106 EIAMLENLRFSAEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARI 165
++ +LEN+RF EE +K EE E K L+ D ++DAF AHR ++ G +I
Sbjct: 127 DVVLLENVRFYKEE-GSKSTEEREA--MAKILASYGDVYISDAFGTAHRDSATMTGIPKI 183
Query: 166 KPM-IMGFLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGG 224
G+LME+EI K + P V ++GGAKV D +++ +N+L+R D +L GG
Sbjct: 184 LGHGAAGYLMEKEISYFAKVLGNPPRPLVAIVGGAKVSDKIQLLDNMLQR--IDYLLIGG 241
Query: 225 LVANVFTLAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE 284
+A F A+G+ +G E K + L+K AE + V P+D +
Sbjct: 242 AMAYTFLKAQGYSIGISMCEESKLEFARSLLKKAE----DRKVQVILPIDHVCHTEFKAV 297
Query: 285 EIYLLSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVF 344
+ L++E + + + +DIG +TIEKY I K K + NGPMGVFE ++ GT +
Sbjct: 298 DSPLITEDQNIPEGHMALDIGPKTIEKYVQTIGKCKSAIWNGPMGVFEMVPYSKGTFAIA 357
Query: 345 KAIA----ESEAFSVLGGGHSIASIQKYG-IEGITHISTGGGAMLTFFAGEELPVLRAL 398
KA+ E S++GGG S ++ + G + ++H+STGGGA L G+ LP + L
Sbjct: 358 KAMGRGTHEHGLMSIIGGGDSASAAELSGEAKRMSHVSTGGGASLELLEGKTLPGVTVL 416
>sp|P27362|PGK_PLAFA PHOSPHOGLYCERATE KINASE >gi|84239|pir||JU0475 phosphoglycerate
kinase (EC 2.7.2.3) - malaria parasite (Plasmodium
falciparum) >gi|160592|gb|AAA29727.1| (M59249)
3-phosphoglycerate kinase [Plasmodium falciparum]
Length = 416
Score = 201 bits (505), Expect = 2e-50
Identities = 134/409 (32%), Positives = 224/409 (54%), Gaps = 32/409 (7%)
Query: 11 NKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGA-RVVVGTHQGKP---YSEDY 66
NK V +RVD N P+++G I R A LPTI +L + GA ++++ +H G+P +E Y
Sbjct: 16 NKKVLVRVDFNVPIENGIIKDTNRITATLPTINHLKKEGASKIILISHCGRPDGLRNEKY 75
Query: 67 ATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPI- 125
T + A L LL + V ++ D G+ +KI K + +LENLRF EE + K +
Sbjct: 76 -TLKPVAETLKGLLGEEVLFLNDCVGKEVEDKINAAKENSVILLENLRFHIEE-EGKGVD 133
Query: 126 ----------EECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLME 175
E+ EK F L+K+ D +NDAF AHR+ S+VG ++ GFLM+
Sbjct: 134 ANGNKVKANKEDVEK--FQNDLTKLADVFINDAFGTAHRAHSSMVG-VKLNVKASGFLMK 190
Query: 176 REIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFT-LAK 234
+E+E KA + + P + +LGGAKV D +++ +N+L + D ++ GG +A F +
Sbjct: 191 KELEYFSKALENPQRPLLAILGGAKVSDKIQLIKNLLDK--VDRMIIGGGMAYTFKKVLN 248
Query: 235 GFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAI-DYKGDREEIYLLSEKR 293
+G + K + E+++ A+ + + PVDF I D + ++++
Sbjct: 249 NMKIGTSLFDEAGSKIVGEIMEKAKAKNVQIF----LPVDFKIADNFDNNANTKFVTDEE 304
Query: 294 ELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAE---S 350
+ +++ +D G ++IE Y+D+I+ +K V+ NGP GVFE FA G++E + E
Sbjct: 305 GIPDNWMGLDAGPKSIENYKDVILTSKTVIWNGPQGVFEMPNFAKGSIECLNLVVEVTKK 364
Query: 351 EAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
A +++GGG + + +++ + I+H+STGGGA L G+ELP + AL
Sbjct: 365 GAITIVGGGDTASLVEQQNKKNEISHVSTGGGASLELLEGKELPGVLAL 413
>gi|10383781 3-phosphoglycerate kinase; Pgk1p [Saccharomyces cerevisiae]
>gi|129930|sp|P00560|PGK_YEAST PHOSPHOGLYCERATE KINASE
>gi|1197055|gb|AAA88729.1| (J01342) 3-phosphoglycerate
kinase [Saccharomyces cerevisiae]
Length = 416
Score = 199 bits (501), Expect = 5e-50
Identities = 140/405 (34%), Positives = 215/405 (52%), Gaps = 25/405 (6%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPYSE 64
D + +K VF+RVD N P+ KI S+ R A LPTIKY+LE+ R VV+ +H G+P E
Sbjct: 11 DLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGRPNGE 70
Query: 65 --DYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKN 122
+ + A+ L +LL + V ++ D G ++ PG + +LENLR+ EE +
Sbjct: 71 RNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHIEEEGS 130
Query: 123 KPI---------EECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFL 173
+ + E+ +K F +LS + D +NDAF AHR+ S+VGF + GFL
Sbjct: 131 RKVDGQKVKASKEDVQK--FRHELSSLADVYINDAFGTAHRAHSSMVGF-DLPQRAAGFL 187
Query: 174 MEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLA 233
+E+E++ KA + P + +LGGAKV D +++ +N+L + D I+ GG +A FT
Sbjct: 188 LEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDK--VDSIIIGGGMA--FTFK 243
Query: 234 KGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAI-DYKGDREEIYLLSEK 292
K + K G + K EK + V PVDF I D +++K
Sbjct: 244 KVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVV-LPVDFIIADAFSADANTKTVTDK 302
Query: 293 RELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEA 352
+ +Q +D G + + + + KAK +V NGP GVFE E+FA GT + + +S A
Sbjct: 303 EGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSA 362
Query: 353 FS---VLGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELP 393
++GGG + +KYG+ + I+H+STGGGA L G+ELP
Sbjct: 363 AGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELP 407
>sp|P29407|PGK_YARLI PHOSPHOGLYCERATE KINASE >gi|2133236|pir||S68151 phosphoglycerate
kinase (EC 2.7.2.3) - yeast (Yarrowia lipolytica)
>gi|173252|gb|AAC37504.1| (M91598) 3-phosphoglycerate
kinase [Yarrowia lipolytica]
Length = 417
Score = 199 bits (501), Expect = 5e-50
Identities = 135/410 (32%), Positives = 219/410 (52%), Gaps = 24/410 (5%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPYS- 63
D + NK VF+RVD N P+ I ++ R A LP+IKY ++ GA+ V++ +H G+P
Sbjct: 11 DLDLKNKRVFIRVDFNVPLDGTTITNNQRIVAALPSIKYAIDQGAKAVILASHLGRPNGQ 70
Query: 64 --EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV- 120
E Y+ A LS LL + V +++D G E++ + K GE+ +LENLRF EE
Sbjct: 71 RVEKYSLKPVQAE-LSKLLGKPVTFLDDCVGPKVEEEVSKAKDGEVILLENLRFHPEEEG 129
Query: 121 -------KNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFL 173
K + + F K L+ + D VNDAF AHR+ S+VG + GFL
Sbjct: 130 SHKDADGKKIKADPAKVEEFRKSLTSLADVYVNDAFGTAHRAHSSMVGI-ELPQRAAGFL 188
Query: 174 MEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLA 233
+ +E+E KA E P + +LGGAKV D +++ +N+L + A +I+ GG+
Sbjct: 189 VAKELEFFAKALEHPERPFLAILGGAKVSDKIQLIDNLLDKVNA-LIIGGGMAFTFKKTL 247
Query: 234 KGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLSEK 292
+ +G + K + LV+ A+K + PVD+ K ++ ++ ++
Sbjct: 248 ENVKIGNSLFDEDGSKIVAGLVEKAKKNNVKLV----FPVDYVTADKFSKDAKVGHATDA 303
Query: 293 RELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKA---IAE 349
+ + +Q +D G ++IE+++ +I ++K ++ NGP GVFE + FA GT V A +
Sbjct: 304 EGIPDGWQGLDCGPKSIEEFQKVIGESKTILWNGPPGVFEFDNFAKGTKAVLDACVKAVD 363
Query: 350 SEAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
+ A ++GGG + +KYG E ++H+STGGGA L G+ LP + AL
Sbjct: 364 NGATVIIGGGDTATVAKKYGAEDKLSHVSTGGGASLELLEGKTLPGVAAL 413
>sp|P50315|PGK_HALVA PHOSPHOGLYCERATE KINASE >gi|2147021|pir||S65044 phosphoglycerate
kinase (EC 2.7.2.3) - Haloarcula vallismortis
>gi|1009048|gb|AAB03731.1| (L47295) phosphoglycerate
kinase [Haloarcula vallismortis]
Length = 401
Score = 199 bits (501), Expect = 5e-50
Identities = 130/396 (32%), Positives = 212/396 (52%), Gaps = 21/396 (5%)
Query: 14 VFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYSEDYATTEEHA 73
V +R+DLNSP++DG + + RF T+K L + G V V HQG+P +D+ + ++HA
Sbjct: 16 VLVRLDLNSPVEDGTVQDNRRFDRHAETVKELADRGFEVAVLAHQGRPGRDDFVSLDQHA 75
Query: 74 RILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPIEECEKTFF 133
IL++ +++ V++V++ +G A I +L G++ +LEN R +E+ + E +T F
Sbjct: 76 DILADHIDRDVDFVDETYGPQAIHDIADLDSGDVLVLENTRMCDDELPEEDPEVKAQTEF 135
Query: 134 VKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEALMKAYYSKE--SP 191
VK L+ D +NDA++AAHRS SLVGF + G +ME E EA A KE
Sbjct: 136 VKTLAGEFDAYINDAYSAAHRSHASLVGFPLVMDAYAGRVMETEYEA-NTAIAEKEFDGQ 194
Query: 192 RVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLA---KGFDLGRKNIEFMKK 248
V+GG K D + V ++ + D L GG+ V A G+D+ N+ +
Sbjct: 195 VTMVVGGTKATDVIDVMTHLDEK--VDDFLLGGIAGTVPAAAGHPVGYDIDDANLYDEQW 252
Query: 249 KGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGD---REEIYLLSEKRELLNDYQIMDIG 305
+ E + E +L++ + VD A + + D + + + EKR +D+G
Sbjct: 253 EANSEKI---ESMLEDHRDQITLAVDLAYEDENDDRAEQAVDDIDEKR-----LSYLDVG 304
Query: 306 SRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGHSIASI 365
S T+ +Y II +++ V G G+FE E F++GT V +AIA+++ FSV+GGG + +I
Sbjct: 305 SETLMEYSPIIRESEAVFGEGRAGMFEDERFSVGTAGVLEAIADTDCFSVVGGGDTSRAI 364
Query: 366 QKYGIE--GITHISTGGGAMLTFFAGEELPVLRALQ 399
+ YG+E H+S GGA + +L + LQ
Sbjct: 365 EMYGMEEDEFGHVSIAGGAYIRALTRAQLVGVEVLQ 400
>pdb|1QPG| 3-Phosphoglycerate Kinase, Mutation R65q
Length = 415
Score = 199 bits (500), Expect = 6e-50
Identities = 140/405 (34%), Positives = 215/405 (52%), Gaps = 25/405 (6%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPYSE 64
D + +K VF+RVD N P+ KI S+ R A LPTIKY+LE+ R VV+ +H G+P E
Sbjct: 10 DLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGQPNGE 69
Query: 65 --DYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKN 122
+ + A+ L +LL + V ++ D G ++ PG + +LENLR+ EE +
Sbjct: 70 RNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHIEEEGS 129
Query: 123 KPI---------EECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFL 173
+ + E+ +K F +LS + D +NDAF AHR+ S+VGF + GFL
Sbjct: 130 RKVDGQKVKASKEDVQK--FRHELSSLADVYINDAFGTAHRAHSSMVGF-DLPQRAAGFL 186
Query: 174 MEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLA 233
+E+E++ KA + P + +LGGAKV D +++ +N+L + D I+ GG +A FT
Sbjct: 187 LEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDK--VDSIIIGGGMA--FTFK 242
Query: 234 KGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAI-DYKGDREEIYLLSEK 292
K + K G + K EK + V PVDF I D +++K
Sbjct: 243 KVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVV-LPVDFIIADAFSADANTKTVTDK 301
Query: 293 RELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEA 352
+ +Q +D G + + + + KAK +V NGP GVFE E+FA GT + + +S A
Sbjct: 302 EGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSA 361
Query: 353 FS---VLGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELP 393
++GGG + +KYG+ + I+H+STGGGA L G+ELP
Sbjct: 362 AGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELP 406
>sp|P47542|PGK_MYCGE PHOSPHOGLYCERATE KINASE >gi|1361751|pir||B64233 phosphoglycerate
kinase (EC 2.7.2.3) - Mycoplasma genitalium
>gi|3844879|gb|AAC71522.1| (U39710) phosphoglycerate
kinase (pgk) [Mycoplasma genitalium]
Length = 416
Score = 198 bits (499), Expect = 8e-50
Identities = 148/413 (35%), Positives = 218/413 (51%), Gaps = 36/413 (8%)
Query: 8 NYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS-EDY 66
++ NK V LR D N PM +G I R A L TIK+L++ ++V+ +H + S ED
Sbjct: 16 DFQNKTVVLRSDFNVPMINGVISDSERILAGLDTIKFLVKKNCKIVLLSHLSRIKSLEDK 75
Query: 67 ATTEEHARILSNLLNQHVEYVEDIF-----GRYAREKIQELKPGEIAMLENLRF-----S 116
++ + ++ LL Q + V+ F G ++K+Q L GEI +LEN R+
Sbjct: 76 LNNKKSLKPVAELLQQLLPTVKVQFSCKNTGAEVKQKVQALAFGEILLLENTRYCDVNDK 135
Query: 117 AEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLME 175
E VK + + E F L ++ VNDAF AHR S G A+ + +GFLME
Sbjct: 136 GEIVKLESKNDPELAKFWASLGEIF---VNDAFGTAHRKHASNAGIAKYVAKSCIGFLME 192
Query: 176 REIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKG 235
+E++ L S + P V VLGGAKV D LKV EN+L+ AD IL GG + N F AKG
Sbjct: 193 KELKNLSYLIQSPQKPFVVVLGGAKVSDKLKVVENLLK--LADNILIGGGMVNTFLKAKG 250
Query: 236 FDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAID------YKGDREEIYLL 289
+E EL+ A++ILD+ + AID +K +
Sbjct: 251 KATANSLVE-------KELIDVAKQILDKD---THNKIVLAIDQVMGSEFKDQTGITLDV 300
Query: 290 SEK-RELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIA 348
S+K +E Y +D+GS+TI + + AK + NGP+GVFE FA GT ++ + IA
Sbjct: 301 SDKIQEQYQSYMSLDVGSKTIALFESYLKTAKTIFWNGPLGVFEFTNFAKGTSKIGEIIA 360
Query: 349 ESE-AFSVLGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRALQ 399
+++ AFSV+GGG S A++++ + + + ISTGGGA L GEEL + +Q
Sbjct: 361 KNKTAFSVIGGGDSAAAVKQMQLSDQFSFISTGGGASLALIGGEELVGISDIQ 413
>sp|P41757|PGK_CANMA PHOSPHOGLYCERATE KINASE >gi|83923|pir||JT0950 phosphoglycerate
kinase (EC 2.7.2.3) - yeast (Candida maltosa)
>gi|218364|dbj|BAA02040.1| (D12474) phosphoglycerate
kinase [Candida maltosa]
Length = 417
Score = 198 bits (497), Expect = 1e-49
Identities = 135/410 (32%), Positives = 217/410 (52%), Gaps = 24/410 (5%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPYSE 64
D N K VF+RVD N P+ I ++ R A LPTIKY+ E + +++ +H G+P E
Sbjct: 11 DLNVTGKRVFIRVDFNVPLDGKTITNNQRIVAALPTIKYVEEQKPKCIILASHLGRPNGE 70
Query: 65 --DYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKN 122
+ + A L LL Q V +++D G + + G+I +LENLRF EE +
Sbjct: 71 RNEKYSLAPVAAELEKLLGQKVTFLDDCVGPEVTKAVDSATEGQIFLLENLRFHIEEEGS 130
Query: 123 KPIEECEKTF--------FVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLM 174
++ +KT F ++L+ + D VNDAF AHR+ S+VG + GFLM
Sbjct: 131 AKDKDGKKTKADPEAVKKFREQLTSLADVYVNDAFGTAHRAHSSMVGL-EVPERAAGFLM 189
Query: 175 EREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVF-TLA 233
+E+E KA + + P + +LGGAKV D +++ +N+L + D+++ GG +A F +
Sbjct: 190 SKELEYFAKALENPQRPFLAILGGAKVSDKIQLIDNLLDK--VDMLIVGGGMAFTFKKVL 247
Query: 234 KGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLSEK 292
+G + K + LV A+K E PVDF K D++ E+ +
Sbjct: 248 NNMPIGDSLFDEAGAKNVENLVAKAKKNNVELI----LPVDFVTADKFDKDAEVSTADDV 303
Query: 293 RELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVF-KAIAESE 351
+ + + +D G ++ + + D + KAK +V NGP GVFE ++FA GT + A+ +E
Sbjct: 304 TGIPDKWMGLDCGPKSRKLFADAVAKAKTIVWNGPPGVFEFDKFAEGTKSLLDDAVKSAE 363
Query: 352 A--FSVLGGGHSIASIQKYG-IEGITHISTGGGAMLTFFAGEELPVLRAL 398
++GGG + +KYG ++ ++H+STGGGA L G+ELP + AL
Sbjct: 364 VGNIVIIGGGDTATVAKKYGVVDKLSHVSTGGGASLELLEGKELPGVTAL 413
>pdb|3PGK| Phosphoglycerate Kinase (E.C.2.7.2.3) Complex With Atp, Magnesium
Or Manganese, 3-Phosphoglycerate
Length = 416
Score = 197 bits (496), Expect = 2e-49
Identities = 139/405 (34%), Positives = 215/405 (52%), Gaps = 25/405 (6%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPYSE 64
D + +K VF+RVD N P+ KI S+ R A LPTIKY+LE+ R VV+ +H G+P E
Sbjct: 11 DLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGRPNGE 70
Query: 65 --DYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKN 122
+ + A+ L +LL + V ++ D G ++ PG + +LENLR+ EE +
Sbjct: 71 RNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHIEEEGS 130
Query: 123 KPI---------EECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFL 173
+ + E+ +K F +LS + D +NDAF AHR+ S+VGF + GFL
Sbjct: 131 RKVDGQKVKASKEDVQK--FRHELSSLADVYINDAFGTAHRAHSSMVGF-DLPQRAAGFL 187
Query: 174 MEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLA 233
+E+E++ KA + P + +LGGAKV D +++ +N+L + D I+ GG +A FT
Sbjct: 188 LEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDK--VDSIIIGGGMA--FTFK 243
Query: 234 KGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAI-DYKGDREEIYLLSEK 292
K + K E+ K EK + V PVDF I D +++K
Sbjct: 244 KVLENTEIGDSIFDKAVGPEIAKLMEKAKAKGVEVV-LPVDFIIADAFSASANTKTVTDK 302
Query: 293 RELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEA 352
+ +Q +D G + + + + KA V++ NGP GVFE E+FA GT + + +S A
Sbjct: 303 EGIPAGWQGLDNGPESRKLFAATVAKATVILWNGPPGVFEFEKFAAGTKALLDEVVKSSA 362
Query: 353 FS---VLGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELP 393
++GGG + +KYG+ + I+H+STGGGA L G+ELP
Sbjct: 363 AGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELP 407
>sp|P50320|PGKP_ALCEU PHOSPHOGLYCERATE KINASE, PLASMID >gi|976369|gb|AAC43447.1| (U12423)
3-phosphoglycerate kinase [Ralstonia eutropha]
Length = 412
Score = 197 bits (496), Expect = 2e-49
Identities = 140/399 (35%), Positives = 209/399 (52%), Gaps = 34/399 (8%)
Query: 12 KVVFLRVDLNSPMKD-GKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYSEDYATTE 70
K VF+R DLN P G I D R RA +P I L+ GA V+V +H G+P ++ A
Sbjct: 32 KRVFIRADLNVPQDAAGDITDDTRIRASVPAIAACLQAGAAVMVTSHLGRP--QEGAPDP 89
Query: 71 EHA-----RILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPI 125
H+ R LS LL + V + E ++ PG++ +LEN R + E KN
Sbjct: 90 RHSLAPVGRRLSELLGRQVPLLSGW-----TEGGFQVPPGQVVLLENCRMNTGEKKNSDE 144
Query: 126 EECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIM-GFLMEREIEALMKA 184
+K++ + D VNDAF AHR++ + G AR P+ G L+ EI+AL KA
Sbjct: 145 -------LAQKMAALCDVYVNDAFGTAHRAEATTHGIARYAPVACAGPLLAAEIDALGKA 197
Query: 185 YYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNIE 244
P V ++ G+KV L + +++ + D ++ GG +AN F LA G +G+ E
Sbjct: 198 LGQPARPLVAIVAGSKVSTKLTILKSLADK--VDNLVVGGGIANTFMLAAGLKIGKSLAE 255
Query: 245 FMKKKGLLELVKHAEKILDEFYPY---VRTPVDFAIDYKGDREEIYLLSEKRELLNDYQI 301
+L+ A I+D V PVD + + + R++ +D I
Sbjct: 256 -------PDLLADARAIIDIMAARGASVPIPVDVVCAKEFSATAAAAVKDVRDVADDDMI 308
Query: 302 MDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGHS 361
+DIG +T D + A +V NGP+GVFE ++F GT + +AIAES+AFS+ GGG +
Sbjct: 309 LDIGPKTAAMLADQLKAAGTIVWNGPVGVFEFDQFGNGTRVLAQAIAESKAFSIAGGGDT 368
Query: 362 IASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRALQ 399
+A+I KYGI + + +ISTGGGA L F G++LP L L+
Sbjct: 369 LAAIAKYGIADRVGYISTGGGAFLEFLEGKKLPALDVLE 407
>sp|Q01655|PGK_CORGL PHOSPHOGLYCERATE KINASE >gi|419673|pir||B43260 phosphoglycerate
kinase (EC 2.7.2.3) - Corynebacterium glutamicum
>gi|40499|emb|CAA42046.1| (X59403) phosphoglycerate
kinase [Corynebacterium glutamicum]
Length = 403
Score = 197 bits (495), Expect = 2e-49
Identities = 133/392 (33%), Positives = 208/392 (52%), Gaps = 26/392 (6%)
Query: 14 VFLRVDLNSPMKDGKIISD-ARFRAVLPTIKYLLENGARVVVGTHQGKP--YSEDYATTE 70
V +R D N P+ D + I+D R A LPT+K L E GA+V+V H G+ +E Y+
Sbjct: 19 VIVRSDFNVPLNDDREITDKGRIIASLPTLKALSEGGAKVIVMAHLGRQGEVNEKYSLAP 78
Query: 71 EHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPIEECEK 130
A LS+ L Q+V D+ G A E+ L G+I +LEN+RF E +E E+
Sbjct: 79 V-AEALSDELGQYVALAADVVGEDAHERANGLTEGDILLLENVRFDPRETSK---DEAER 134
Query: 131 TFFVKKLSKVI---DYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIEALMKAYYS 187
F ++L+ + V+D F HR+Q S+ A++ P G L+E EI L K S
Sbjct: 135 NRFAQELAALAADNGAFVSDGFGVVHRAQTSVYDIAKLLPHYAGGLVETEISVLEKIAES 194
Query: 188 KESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNIEFMK 247
E+P V VLGG+KV D + V E + + AD I+ GG + F A+G ++ + ++
Sbjct: 195 PEAPYVVVLGGSKVSDKIGVIEALAAK--ADKIIVGGGMCYTFLAAQGHNVQQSLLQEEM 252
Query: 248 KKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIMDIGSR 307
K +L+ +KI+ PVD + +++ + + + + +DIG
Sbjct: 253 KATCTDLLASVDKIV--------LPVDLVAASEFNKDAEKQIVDLDSIPEGWMSLDIGPE 304
Query: 308 TIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAI----AESEAFSVLGGGHSIA 363
+++ + +++ AK + NGPMGVFE F+ GT + A ++AFSV+GGG S A
Sbjct: 305 SVKNFGEVLSTAKTIFWNGPMGVFEFAAFSEGTRASPRPSSMQHAGNDAFSVVGGGDSAA 364
Query: 364 SIQKYGI--EGITHISTGGGAMLTFFAGEELP 393
S++ G+ +G +HISTGGGA L + G+ELP
Sbjct: 365 SVRVLGLNEDGFSHISTGGGASLEYLEGKELP 396
>sp|Q27685|PGKC_LEIME PHOSPHOGLYCERATE KINASE, GLYCOSOMAL (C) >gi|1403361|emb|CAA67113.1|
(X98487) glycosomal phosphoglycerate kinase [Leishmania
mexicana]
Length = 479
Score = 197 bits (495), Expect = 2e-49
Identities = 133/411 (32%), Positives = 210/411 (50%), Gaps = 32/411 (7%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS 63
+ D +K V +RVD N P+K+G+I +D R R+ LPTI+ +L+ G ++ +H G+P
Sbjct: 9 IDDVALKDKKVLIRVDFNVPVKNGEITNDFRIRSALPTIQKVLKEGGSCILMSHLGRPKG 68
Query: 64 ---------------EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIA 108
E+ AT A LS LL + V + D A + +LK G++
Sbjct: 69 ARMSDPKPEKGVRGYEEAATLRPVAAALSELLEKKVAFAPDCLN--ASIYVSKLKRGDVL 126
Query: 109 MLENLRFSAEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPM 168
+LEN+RF EE K E E K L+ D V+DAF AHR ++ G ++
Sbjct: 127 LLENVRFYTEEGSKK---EEEADAMAKVLASYADLYVSDAFGTAHRDSATMTGIPKVLGS 183
Query: 169 -IMGFLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVA 227
G+LME+EI + + P V ++GGAKV D +++ +N+L R + ++ GG +A
Sbjct: 184 GYAGYLMEKEINYFSRVLNNPPRPLVAIVGGAKVSDKIELLDNMLGR--INYLVIGGAMA 241
Query: 228 NVFTLAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIY 287
F A+G +G E K L+L K K E V PVD + + +
Sbjct: 242 YTFQKAQGRKIGISMCEEDK----LDLAKSLLKKAQERGVQVLLPVDHVCNKEFKAVDSP 297
Query: 288 LLSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAI 347
L++E ++ + Y +DIG +TI Y ++I + K + NGPMGVFE ++ GT V KA+
Sbjct: 298 LVTEDVDVPDGYMALDIGPKTIHMYEEVIGRCKSAIWNGPMGVFEMPCYSKGTFAVAKAM 357
Query: 348 A----ESEAFSVLGGGHSIASIQKYG-IEGITHISTGGGAMLTFFAGEELP 393
+ S++GGG + ++ + G + ++H+STGGGA L G+ LP
Sbjct: 358 GTGTQKDGLLSIIGGGDTASAAELSGEAKNMSHVSTGGGASLELLEGKTLP 408
>sp|O74233|PGK_GLOMO PHOSPHOGLYCERATE KINASE >gi|3319309|gb|AAD09406.1| (AF072893)
3-phosphoglycerate kinase [Glomus mosseae]
Length = 416
Score = 196 bits (494), Expect = 3e-49
Identities = 132/409 (32%), Positives = 218/409 (53%), Gaps = 22/409 (5%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPYSE 64
D N +K V +RVD N P+ I ++ R A LPTIKY LE A+ VV+ +H G+P +
Sbjct: 11 DLNVKDKRVLIRVDFNVPLDGTTITNNQRIVAALPTIKYALEQKAKTVVLMSHLGRPDGK 70
Query: 65 --DYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKN 122
D + A+ + LL + V ++ED G ++ GE+ +LENLRF AEE +
Sbjct: 71 KVDKYSLAPVAKEVERLLGKKVTFLEDCVGEGVENYVKNACDGEVILLENLRFHAEEEGS 130
Query: 123 KPIEECEKTF--------FVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLM 174
+ +K F + L+ + D +NDAF AHR+ S+VG + GFL+
Sbjct: 131 SKGPDGKKVKADLEKVKEFRRSLTALGDVYINDAFGTAHRAHSSMVG-VELPQKAAGFLV 189
Query: 175 EREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAK 234
++E+E KA S E P + +LGGAKV D +++ +N++ + +I+ GG+ +
Sbjct: 190 KKELEYFAKALESPERPFLAILGGAKVSDKIQLIDNLIAK-VDSLIICGGMAFTFKKTLE 248
Query: 235 GFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLSEKR 293
+G + K + E+++ A+K E V PVD+ K ++ ++ +++
Sbjct: 249 NVKIGNSLFDADGAKTVGEVMEKAKKHDVE----VVLPVDYITADKFAKDAQVGYATDQE 304
Query: 294 ELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALG---TVEVFKAIAES 350
+ + + +D G +++E Y+ I KAK ++ NGP GVFE + FA G T++ A+S
Sbjct: 305 GIPDGWMGLDCGEKSVELYKQTIAKAKTILWNGPAGVFEFDNFAKGTKATLDCAVEAAQS 364
Query: 351 EAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
++GGG + KYG+E ++H+STGGGA L G++LP + AL
Sbjct: 365 GKIVIIGGGDTATVAAKYGVEDKLSHVSTGGGASLELLEGKDLPGVSAL 413
>pir||KIBYG phosphoglycerate kinase (EC 2.7.2.3) - yeast (Saccharomyces
cerevisiae) >gi|1907155|emb|CAA42329.1| (X59720)
YCR012w, len:416 [Saccharomyces cerevisiae]
Length = 416
Score = 196 bits (493), Expect = 4e-49
Identities = 139/405 (34%), Positives = 214/405 (52%), Gaps = 25/405 (6%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPYSE 64
D + +K VF+RVD N P+ KI S+ R A LPTIKY+LE+ R VV+ +H G+P E
Sbjct: 11 DLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGRPNGE 70
Query: 65 --DYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKN 122
+ + A+ L +LL + V ++ D ++ PG + +LENLR+ EE +
Sbjct: 71 RNEKYSLAPVAKELQSLLGKDVTFLNDCVRPEVEAAVKASAPGSVILLENLRYHIEEEGS 130
Query: 123 KPI---------EECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFL 173
+ + E+ +K F +LS + D +NDAF AHR+ S+VGF + GFL
Sbjct: 131 RKVDGQKVKASKEDVQK--FRHELSSLADVYINDAFGTAHRAHSSMVGF-DLPQRAAGFL 187
Query: 174 MEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLA 233
+E+E++ KA + P + +LGGAKV D +++ +N+L + D I+ GG +A FT
Sbjct: 188 LEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDK--VDSIIIGGGMA--FTFK 243
Query: 234 KGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAI-DYKGDREEIYLLSEK 292
K + K G + K EK + V PVDF I D +++K
Sbjct: 244 KVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVV-LPVDFIIADAFSADANTKTVTDK 302
Query: 293 RELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEA 352
+ +Q +D G + + + + KAK +V NGP GVFE E+FA GT + + +S A
Sbjct: 303 EGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSA 362
Query: 353 FS---VLGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELP 393
++GGG + +KYG+ + I+H+STGGGA L G+ELP
Sbjct: 363 AGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELP 407
>gb|AAG34561.1|AF316577_1 (AF316577) phosphoglycerate kinase [Dictyostelium discoideum]
Length = 420
Score = 196 bits (492), Expect = 5e-49
Identities = 141/417 (33%), Positives = 217/417 (51%), Gaps = 49/417 (11%)
Query: 12 KVVFLRVDLNSPM-KDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPYSEDYATT 69
K V +RVD N P+ K+ I S R A +PT++Y L+NGA+ +V+ +H G+P D
Sbjct: 20 KRVLIRVDYNVPLDKNNNITSTQRIDASIPTLEYCLKNGAKSIVLMSHLGRP---DGLVK 76
Query: 70 EEHA-----RILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE----- 119
E++ ++L + L + ++++ D G ++ + G + +LENLRF EE
Sbjct: 77 PEYSLKPVVKVLEDQLKRPIKFLSDCVGEQVEKECANPEEGTVILLENLRFHIEEEGSGV 136
Query: 120 ------VKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFL 173
VK P + E F + L+K+ D VNDAF AHR+ S+VG + GFL
Sbjct: 137 DAEGKKVKANPEKVKE---FRESLTKLGDVYVNDAFGTAHRAHSSMVGI-NLPQKAAGFL 192
Query: 174 MEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLA 233
M++E+E KA S P + +LGGAKV D +K+ EN+L + D ++ GG +A FT
Sbjct: 193 MKKELEYFAKALESPSKPFLAILGGAKVXDKIKLIENLLYK--VDEMIIGGGMA--FTFK 248
Query: 234 K-------GFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-E 285
K G L K E + K + + K+ K+ PVD+ I K D +
Sbjct: 249 KFIDNKEIGSSLFEKTAEQITKDIIAKAAKNNVKL--------HFPVDYVIADKFDNDAN 300
Query: 286 IYLLSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFK 345
I +++ + + + +D G TI++ RD I +AK +V NGPMGVFE+ F GT
Sbjct: 301 IKTVTQDQGIPEGWMGLDCGPETIKENRDTISRAKTIVWNGPMGVFEKSNFEAGTKAAMD 360
Query: 346 AIAESE---AFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
+ + A +++GGG + KY E ++H+STGGGA L G+ELP + AL
Sbjct: 361 DVVNATTNGAITIIGGGDTATCAAKYNTEDKVSHVSTGGGASLELLEGKELPGVTAL 417
>sp|O94123|PGK_AGABI PHOSPHOGLYCERATE KINASE >gi|3873556|emb|CAA66195.1| (X97580)
3-phosphoglycerate kinase [Agaricus bisporus]
>gi|5911461|emb|CAA62559.1| (X91105) phosphoglycerate
kinase [Agaricus bisporus]
Length = 416
Score = 195 bits (491), Expect = 7e-49
Identities = 130/404 (32%), Positives = 220/404 (54%), Gaps = 22/404 (5%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGA-RVVVGTHQGKPYSE 64
D K V +RVD NSP++DGKI + AR A LPTIKY L+NGA +V++ +H G+P +
Sbjct: 11 DLALTGKRVLIRVDFNSPIQDGKITNPARINAALPTIKYALDNGASKVILMSHLGRPDGK 70
Query: 65 DYA--TTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKN 122
+ + + A L LL + V ++ D G + + E G + +LENLRF EE +
Sbjct: 71 AISKYSLKPVASELEKLLKKPVFFLHDCVGPDIEKAVLEAPEGAVVLLENLRFHIEEEGS 130
Query: 123 KPIEECEK--------TFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLM 174
EE +K T F ++L+++ D VNDAF AHR+ S+VG ++ GFL+
Sbjct: 131 AKNEEGKKIKADPSKVTQFREQLTRLGDVYVNDAFGTAHRAHSSMVGI-KLPRRASGFLV 189
Query: 175 EREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAK 234
++E++ KA + E P + +LGGAKV D +++ EN+L + +++ GG+ +
Sbjct: 190 KKELDYFAKALENPERPFLAILGGAKVSDKIQLIENMLDK-VNCLVIGGGMAFTFKKTMQ 248
Query: 235 GFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIY-LLSEKR 293
+G + + + +V+ A+K E + PVD+ + K D + ++++
Sbjct: 249 NVAIGNSLFDKPGSEKVAGIVEKAKKNNVE----IVFPVDYVVGDKFDANANHKIVTDDE 304
Query: 294 ELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAES--- 350
+ + + +D+G ++ E +R+ ++KAK ++ NGP GVFE FA G+ + A E+
Sbjct: 305 GVPDGWMGLDVGPKSNELFREAVLKAKTILWNGPPGVFEFPAFAKGSKVLLDATVEAVQK 364
Query: 351 EAFSVLGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELP 393
A ++GGG + + + E ++H+STGGGA L G+ LP
Sbjct: 365 GATVIVGGGDTATVVANHDAEEKLSHVSTGGGASLELLEGKTLP 408
>sp|P14828|PGK_KLULA PHOSPHOGLYCERATE KINASE >gi|66895|pir||KIVKGL phosphoglycerate
kinase (EC 2.7.2.3) - yeast (Kluyveromyces marxianus
var. lactis) >gi|2867|emb|CAA35646.1| (X17654)
3-phosphoglycerate kinase (AA 1-416) [Kluyveromyces
lactis]
Length = 416
Score = 195 bits (490), Expect = 9e-49
Identities = 133/403 (33%), Positives = 218/403 (54%), Gaps = 21/403 (5%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPYSE 64
D + K VF+RVD N P+ KI S+ R A LPTI+Y+LE + +V+ +H G+P E
Sbjct: 11 DLDVTGKRVFIRVDFNVPLDGKKITSNQRIVAALPTIQYVLEKKPKAIVLASHLGRPNGE 70
Query: 65 --DYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKN 122
D + A LS LL + V ++ D G + K GE+ +LENLRF EE +
Sbjct: 71 VNDKYSLAPVADELSRLLQKPVTFLHDCVGEEVTNAVNNAKDGEVFLLENLRFHIEEEGS 130
Query: 123 KPI-------EECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLME 175
+ + ++ T F ++LS + D VNDAF AHR+ S+VGF + GFL+
Sbjct: 131 RKVDGNKVKADKAAVTKFREQLSSLADVYVNDAFGTAHRAHSSIVGF-DLPNRAAGFLLS 189
Query: 176 REIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKG 235
+E++ KA + P + +LGGAKV D +++ +N+L + +I+ GG+ + +
Sbjct: 190 KELQYFAKALENPTRPFLAILGGAKVADKIQLIDNLLDK-VDSLIIGGGMAFTFKKVLEN 248
Query: 236 FDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLSEKRE 294
++G + + + +LV+ A+K + + P DF I K + ++++K
Sbjct: 249 TEIGDSIYDAAGAELVPKLVEKAKKNNVK----IVLPTDFVIGDKFSADANTKVVTDKEG 304
Query: 295 LLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKA-IAESEAF 353
+ + +Q +D G + + + + +AK +V NGP GVFE FA GT + A +A S+A
Sbjct: 305 IPSGWQGLDNGPESRKAFAATVAEAKTIVWNGPPGVFEFAPFAKGTEALLDAVVASSQAG 364
Query: 354 S--VLGGGHSIASIQKYG-IEGITHISTGGGAMLTFFAGEELP 393
+ ++GGG + +KYG ++ I+H+STGGGA L G+ELP
Sbjct: 365 NNVIIGGGDTATVAKKYGVVDKISHVSTGGGASLELLEGKELP 407
>sp|P33161|PGK_PENCI PHOSPHOGLYCERATE KINASE >gi|320113|pir||S28922 phosphoglycerate
kinase (EC 2.7.2.3) - Penicillium citrinum
>gi|298258|gb|AAB25344.1| (S54965) 3-phosphoglycerate
kinase, PGK {EC 2.7.2.3} [Penicillium citrinum, Peptide,
417 aa]
Length = 417
Score = 194 bits (489), Expect = 1e-48
Identities = 133/410 (32%), Positives = 214/410 (51%), Gaps = 23/410 (5%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDA-RFRAVLPTIKYLLENGAR-VVVGTHQGKPYS 63
D + K V +RVD N P+ + K +++ R LPTIKY ++NGA+ VV+ +H G+P
Sbjct: 11 DVDLKGKRVLIRVDFNVPLDENKNVTNPQRIVGALPTIKYAIDNGAKAVVLMSHLGRPDG 70
Query: 64 E--DYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV- 120
+ + + +L LL + V + ED G E + + G++ +LENLRF AEE
Sbjct: 71 KVNPKYSLKPVVPVLEKLLGKSVTFAEDCVGPQTEETVNKASDGQVILLENLRFHAEEEG 130
Query: 121 -------KNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFL 173
K ++ + F K L+ + D VNDAF AHR+ S+VG + GFL
Sbjct: 131 SSKDAEGKKVKADKADVDAFRKGLTALGDVYVNDAFGTAHRAHSSMVG-VDLPQKAAGFL 189
Query: 174 MEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLA 233
+++E+E KA S P + +LGGAKV D +++ +N+L + +I+TGG+
Sbjct: 190 VKKELEYFAKALESPARPFLAILGGAKVSDKIQLIDNLLPK-VNSLIITGGMAFTFKKTL 248
Query: 234 KGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLSEK 292
+ +G + K + E+V+ A+K E + PVD+ K + + ++
Sbjct: 249 ENVKIGNSLFDEAGSKIVGEIVEKAKKYNVE----IVLPVDYVTADKFSADATVGAATDA 304
Query: 293 RELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKA---IAE 349
+ + Y +D+G +++ Y+ I +AK ++ NGP GVFE + FA T A AE
Sbjct: 305 TGIPDGYMGLDVGPESVKLYQKTIAEAKTILWNGPPGVFELKPFASATEATLDAAVKAAE 364
Query: 350 SEAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
S + ++GGG + KY +E I+H+STGGGA L G+ELP + AL
Sbjct: 365 SGSIVIIGGGDTATVAAKYKVEDKISHVSTGGGASLELLEGKELPGVAAL 414
>pir||I39554 phosphoglycerate kinase (EC 2.7.2.3) - Alcaligenes eutrophus
Length = 412
Score = 194 bits (489), Expect = 1e-48
Identities = 139/399 (34%), Positives = 208/399 (51%), Gaps = 34/399 (8%)
Query: 12 KVVFLRVDLNSPMKD-GKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYSEDYATTE 70
K VF+R DLN P G I D R RA +P I L+ GA V+V +H G+P ++ A
Sbjct: 32 KRVFIRADLNVPQDAAGDITDDTRIRASVPAIAACLQAGAAVMVTSHLGRP--QEGAPDP 89
Query: 71 EHA-----RILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPI 125
H+ R LS LL + V + E ++ PG++ +LEN R + E KN
Sbjct: 90 RHSLAPVGRRLSELLGRQVPLLSGW-----TEGGFQVPPGQVVLLENCRMNTGEKKNSDE 144
Query: 126 EECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIM-GFLMEREIEALMKA 184
+K++ + D VNDAF AHR++ + G AR P+ G L+ EI+AL KA
Sbjct: 145 -------LAQKMAALCDVYVNDAFGTAHRAEATTHGIARYAPVACAGPLLAAEIDALGKA 197
Query: 185 YYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNIE 244
P ++ G+KV L + +++ + D ++ GG +AN F LA G +G+ E
Sbjct: 198 LGQPARPLWAIVAGSKVSTKLTILKSLADK--VDNLVVGGGIANTFMLAAGLKIGKSLAE 255
Query: 245 FMKKKGLLELVKHAEKILDEFYPY---VRTPVDFAIDYKGDREEIYLLSEKRELLNDYQI 301
+L+ A I+D V PVD + + + R++ +D I
Sbjct: 256 -------PDLLADARAIIDIMAARGASVPIPVDVVCAKEFSATAAAAVKDVRDVADDDMI 308
Query: 302 MDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGHS 361
+DIG +T D + A +V NGP+GVFE ++F GT + +AIAES+AFS+ GGG +
Sbjct: 309 LDIGPKTAAMLADQLKAAGTIVWNGPVGVFEFDQFGNGTRVLAQAIAESKAFSIAGGGDT 368
Query: 362 IASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRALQ 399
+A+I KYGI + + +ISTGGGA L F G++LP L L+
Sbjct: 369 LAAIAKYGIADRVGYISTGGGAFLEFLEGKKLPALDVLE 407
>sp|O60101|PGK_SCHPO PHOSPHOGLYCERATE KINASE >gi|7492300|pir||T39450 phosphoglycerate
kinase - fission yeast (Schizosaccharomyces pombe)
>gi|3184107|emb|CAA19322.1| (AL023780) phosphoglycerate
kinase [Schizosaccharomyces pombe]
Length = 414
Score = 194 bits (488), Expect = 2e-48
Identities = 133/408 (32%), Positives = 215/408 (52%), Gaps = 22/408 (5%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPYSE 64
D + K V +RVD N P+ +I ++AR LPTIKY LE + V++ +H G+P
Sbjct: 11 DVDLKGKNVLIRVDFNVPLDGDRITNNARIVGALPTIKYALEQQPKAVILMSHLGRPNGA 70
Query: 65 DYA--TTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE--- 119
A + + A LS LL + V++++D G + +E K GE+ +LENLRF EE
Sbjct: 71 RVAKYSLKPVAAELSKLLGKPVKFLDDCVGPEVEKACKEAKGGEVILLENLRFHIEEEGS 130
Query: 120 --VKNKPIEECEKTF--FVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLME 175
V K ++ F K L+ + D VNDAF AHR+ S+VG P + GFLM+
Sbjct: 131 AKVDGKKVKADASAVEAFRKSLTSLGDIFVNDAFGTAHRAHSSMVGVDL--PRVSGFLMK 188
Query: 176 REIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKG 235
+E++ KA + P + +LGGAKV D +++ +N+L + +I+ GG+ + G
Sbjct: 189 KELDYFSKALENPARPFLAILGGAKVADKIQLIDNLLDK-VNRLIICGGMAFTFLKVLNG 247
Query: 236 FDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLSEKRE 294
+G + K + ++ A+K E + PVDF K D++ ++ + +
Sbjct: 248 MKIGDSLFDEAGSKNVESMMAKAKKNNVEVF----LPVDFVTADKFDKDAKVGSATAEEG 303
Query: 295 LLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKA---IAESE 351
+ + + +D G ++ K+ ++I +K +V NGP GVFE + FA GT + A E+
Sbjct: 304 IPDGWMGLDCGPKSSAKFAEVITTSKTIVWNGPAGVFEFDNFAKGTKSMLDACVKTCEAG 363
Query: 352 AFSVLGGGHSIASIQKYGIE-GITHISTGGGAMLTFFAGEELPVLRAL 398
++GGG + +KYG E ++H+STGGGA L G+ LP + AL
Sbjct: 364 NVVIVGGGDTATVAKKYGKEDALSHVSTGGGASLELLEGKALPGVVAL 411
>sp|P41756|PGK_ASPOR PHOSPHOGLYCERATE KINASE >gi|541651|dbj|BAA05843.1| (D28484)
phosphoglycerate kinase [Aspergillus oryzae]
Length = 417
Score = 193 bits (486), Expect = 3e-48
Identities = 139/416 (33%), Positives = 221/416 (52%), Gaps = 35/416 (8%)
Query: 6 DFNYHNKVVFLRVDLNSPMK-DGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKP-- 61
D + +K V +RVD N P+ D KI ++ R LPTIKY +ENGA+ VV+ +H G+P
Sbjct: 11 DVDLKDKRVLIRVDFNVPLDADKKITNNQRIVGALPTIKYAIENGAKAVVLMSHLGRPDG 70
Query: 62 -----YSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFS 116
YS TE L LL++ V + E+ G+ E + + G+I +LENLRF
Sbjct: 71 KANPKYSLKPVATE-----LEKLLSKSVIFAENCVGKETEEIVNKATGGQIILLENLRFH 125
Query: 117 AEEVKNKPIEECEKTF--------FVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPM 168
AEE + E +K F K L+ + D +NDAF AHR+ S+VG +
Sbjct: 126 AEEEGSSKDAEGKKVKADKEKVEEFRKGLTALGDVYINDAFGTAHRAHSSMVG-VDLPQK 184
Query: 169 IMGFLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVAN 228
GFL+++E+E KA S + P + +LGGAKV D +++ +N+L + +I+TG +
Sbjct: 185 ASGFLVKKELEYFAKALESPQRPFLAILGGAKVSDKIQLIDNLLPK-VNSLIITGAMAFT 243
Query: 229 VFTLAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDF--AIDYKGDREEI 286
+ +G + K + ++V+ A+K + + PVD+ A + D +
Sbjct: 244 FKKTLENVKIGNSLFDEAGSKIVGDIVEKAKKNNVK----IVLPVDYVTADKFAADAKTG 299
Query: 287 YLLSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALG---TVEV 343
Y ++ + + Y +D+G +++E Y+ I +AK ++ NGP GVFE E FA T++
Sbjct: 300 YA-TDADGIPDGYMGLDVGEKSVELYKKTIAEAKTILWNGPPGVFELEPFANATKKTLDA 358
Query: 344 FKAIAESEAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
A A+S + ++GGG + KYG E ++H+STGGGA L G+ LP + AL
Sbjct: 359 AVAAAQSGSIVIIGGGDTATVAAKYGAEAKLSHVSTGGGASLELLEGKVLPGVDAL 414
>pir||S76392 phosphoglycerate kinase (EC 2.7.2.3) - Synechocystis sp. (strain
PCC 6803) >gi|1653609|dbj|BAA18521.1| (D90915)
phosphoglycerate kinase [Synechocystis sp.]
Length = 374
Score = 193 bits (485), Expect = 3e-48
Identities = 132/383 (34%), Positives = 204/383 (52%), Gaps = 20/383 (5%)
Query: 23 PMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYSE--DYATTEEHARILSNLL 80
P+ +G I D R RA LPTIK LL GA+V++G+H G+P + D L LL
Sbjct: 2 PLDNGSITDDTRIRAALPTIKDLLSKGAKVILGSHFGRPKGKVVDSMRLTPVGDRLGELL 61
Query: 81 NQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPIEECEKTFFVKKLSKV 140
Q V +D G KI L G +A+LENLRF A EE F K L+
Sbjct: 62 GQPVVKCDDCIGAEVTAKIASLPNGGVALLENLRFHAG-------EEGNDAEFAKALAAN 114
Query: 141 IDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMEREIEALMKAYYSKESPRVYVLGGA 199
D VNDAF AHR+ S G + P + G+L+E+E++ L A + + P V ++GG+
Sbjct: 115 ADLYVNDAFGTAHRAHASTEGVTHFLSPNVAGYLIEKELQFLQGAIEAPKRPLVAIVGGS 174
Query: 200 KVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNIEFMKKKGLLELVKHAE 259
KV + V E +L + D ++ GG + F A+G + G+ +E K L+ A+
Sbjct: 175 KVSSKIGVIETLLDK--CDKLIIGGGMIFTFYKAQGLNTGKSLVEEDKLDLAKSLMAKAK 232
Query: 260 KILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIMDIGSRTIEKYRDIIMKA 319
+ EF + T V A ++ D + + + + + +DIG +++ ++D +
Sbjct: 233 EKGVEF--LLPTDVVVADNFAPDANAQTVGVD--AIPDGWMGLDIGPDSVKTFQDALAGC 288
Query: 320 KVVVANGPMGVFEREEFALGTVEVFKAIAE---SEAFSVLGGGHSIASIQKYGI-EGITH 375
V+ NGPMGVFE ++FA+GT + ++AE S +++GGG S+A+++K G+ E ++H
Sbjct: 289 GTVIWNGPMGVFEFDKFAVGTEAIACSLAELTASGTVTIIGGGDSVAAVEKVGVAEKMSH 348
Query: 376 ISTGGGAMLTFFAGEELPVLRAL 398
ISTGGGA L G+ LP + AL
Sbjct: 349 ISTGGGASLELLEGKVLPGIAAL 371
>sp|P91427|PGK_CAEEL PROBABLE PHOSPHOGLYCERATE KINASE >gi|7507007|pir||T29198
hypothetical protein T03F1.3 - Caenorhabditis elegans
>gi|1825605|gb|AAB42230.1| (U88169) similar to
phosphoglycerate kinase; coded for by C. elegans cDNA
yk61f4.5; coded for by C. elegans cDNA yk69b6.5; coded
for by [Caenorhabditis elegans]
Length = 417
Score = 192 bits (483), Expect = 6e-48
Identities = 137/413 (33%), Positives = 218/413 (52%), Gaps = 26/413 (6%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKP- 61
+ N K V +RVD N P+KDGKI ++ R A +PTI++ L NGA+ VV+ +H G+P
Sbjct: 9 IDQLNLAGKRVLIRVDFNVPLKDGKITNNQRIAAAVPTIQHALSNGAKSVVLMSHLGRPD 68
Query: 62 -YSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE- 119
+D T + A L LL + V +++D G + PG + +LENLR+ EE
Sbjct: 69 GRRQDKYTLKPVAEELKALLKKDVLFLDDCVGSEVEAACADPAPGSVILLENLRYHLEEE 128
Query: 120 --------VKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMG 171
K K K F + L+K+ D VNDAF AHR+ S+VG G
Sbjct: 129 GKGVDASGAKVKADSAAVKK-FRESLTKLGDIYVNDAFGTAHRAHSSMVGVEH-SQRASG 186
Query: 172 FLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFT 231
FL++ E+ KA + P + +LGGAKV D +++ +N+L + ++I+ GG+
Sbjct: 187 FLLKNELSYFSKALDNPARPFLAILGGAKVADKIQLIKNLLDK-VNEMIIGGGMAYTFLK 245
Query: 232 LAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAI-DYKGDREEIYLLS 290
+A+G +G + K + EL++ A+ + + PVDF I D + ++
Sbjct: 246 VAQGVKIGNSLYDEEGAKIVNELLEAAKAKGVQ----IHLPVDFVIADKFAEDATSKTVT 301
Query: 291 EKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTV----EVFKA 346
+ + + + +D+G + + + I +AK +V NGP GVFE ++FA GT EV KA
Sbjct: 302 AEEGVPDGHMGLDVGPESSKIFAAAIQRAKTIVWNGPAGVFEFDKFATGTKSLMDEVVKA 361
Query: 347 IAESEAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
A + A +++GGG + + +KY E ++H+STGGGA L G+ LP + AL
Sbjct: 362 TA-AGAITIIGGGDTATAAKKYNTEDKVSHVSTGGGASLELLEGKVLPGVDAL 413
>sp|P50319|PGKC_ALCEU PHOSPHOGLYCERATE KINASE, CHROMOSOMAL >gi|2117891|pir||I39551
phosphoglycerate kinase (EC 2.7.2.3) - Alcaligenes
eutrophus >gi|976365|gb|AAC43444.1| (U12422)
3-phosphoglycerate kinase [Ralstonia eutropha]
Length = 413
Score = 192 bits (482), Expect = 8e-48
Identities = 137/398 (34%), Positives = 207/398 (51%), Gaps = 34/398 (8%)
Query: 12 KVVFLRVDLNSPMKD-GKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYSEDYATTE 70
K VF+R DLN P G I D R RA +P I L+ GA V+V +H G+P ++ A
Sbjct: 33 KRVFIRADLNVPQDAAGAITDDTRIRASVPAIAACLQAGAAVMVTSHLGRP--QEGAPDP 90
Query: 71 EHA-----RILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPI 125
H+ R LS LL + V + E ++ PG++ +LEN R + E KN
Sbjct: 91 RHSLAPVGRRLSELLGRQVPLLSGW-----TEGGFQVPPGQVVLLENCRMNTGEKKNSDE 145
Query: 126 EECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIM-GFLMEREIEALMKA 184
+K++ + D VNDAF AHR++ + G AR P+ G L+ EI+AL KA
Sbjct: 146 -------LAQKMAALCDVYVNDAFGTAHRAEATTHGIARYAPIACAGPLLAAEIDALGKA 198
Query: 185 YYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNIE 244
P V ++ G+KV L + +++ + D ++ GG +AN F LA G +G+ E
Sbjct: 199 LGQPARPLVAIVAGSKVSTKLTILKSLADK--VDNLIVGGGIANTFMLAAGLKIGKSLAE 256
Query: 245 FMKKKGLLELVKHAEKILDEFY---PYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQI 301
+L+ A I+D V PVD + + + +++ +D I
Sbjct: 257 -------PDLLADARAIIDIMARRGASVPIPVDVVCAKEFSATAAATVKDVKDVADDDMI 309
Query: 302 MDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGHS 361
+DIG +T + + A +V NGP+GVFE ++F GT + +AIAES+AFS+ GGG +
Sbjct: 310 LDIGPKTAAMLAEQLKAAGTIVWNGPVGVFEFDQFGNGTRVLAQAIAESKAFSIAGGGDT 369
Query: 362 IASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRAL 398
+A+I K+GI + + +ISTGGGA L F G+ LP L L
Sbjct: 370 LAAIAKHGIADRVGYISTGGGAFLEFLEGKTLPALAVL 407
>sp|P41760|PGK1_TRYCO PHOSPHOGLYCERATE KINASE, CYTOSOLIC >gi|567899|gb|AAC37222.1|
(L37337) phosphoglycerate kinase [Trypanosoma
congolense] >gi|567903|gb|AAC37225.1| (L37336)
phosphoglycerate kinase [Trypanosoma congolense]
Length = 420
Score = 191 bits (481), Expect = 1e-47
Identities = 127/414 (30%), Positives = 211/414 (50%), Gaps = 35/414 (8%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS 63
+ + + K +RVD N P+K G I +D R R+ LPTI+ +L G ++ +H G+P
Sbjct: 9 INECDLKGKKTLVRVDFNVPVKGGVITNDYRIRSALPTIQKVLNEGGSCILMSHLGRPKG 68
Query: 64 ------------------EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPG 105
E+ AT A+ L LL++ V + D A + ++++ PG
Sbjct: 69 ISISEAAAVRSAGKVPGYEEAATLRPVAQRLGELLSKPVVFAPDCLD--AADVVKKMSPG 126
Query: 106 EIAMLENLRFSAEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARI 165
++ +LEN+RF EE K E E+ K L+ D V+DAF AHR ++ G ++
Sbjct: 127 DVVLLENVRFYREEGSKK---EEEREAMAKVLASYGDIFVSDAFGTAHRDSATMTGIPKV 183
Query: 166 KPM-IMGFLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGG 224
G+LME+EI K + P V ++GG+KV D +++ +N+L+R D +L GG
Sbjct: 184 LGHGAAGYLMEKEISYFSKVLGNPPRPLVAIVGGSKVSDKIQLLDNMLQR--IDYLLIGG 241
Query: 225 LVANVFTLAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE 284
+A F A+G +G M ++ L+L + K ++ V PVD +
Sbjct: 242 AMAYTFLKAQGHRIGTS----MCEEDRLDLARSLLKKAEDRKVQVLLPVDHVCHTEFKAV 297
Query: 285 EIYLLSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVF 344
+ +++ ++ + + +DIG +TI Y + I K K + NGPMGVFE ++ GT V
Sbjct: 298 DTPVVTADADIPDGHMALDIGPKTIANYVETIGKCKSAIWNGPMGVFEMTPYSKGTFAVA 357
Query: 345 KAIAE----SEAFSVLGGGHSIASIQKYG-IEGITHISTGGGAMLTFFAGEELP 393
KA+ + + S++GGG S ++ ++ G ++H+STGGGA L G+ LP
Sbjct: 358 KAMGDCTQKNGLMSIIGGGDSASAAEQSGEATRMSHVSTGGGASLELLEGKTLP 411
>sp|Q27684|PGKB_LEIME PHOSPHOGLYCERATE KINASE, CYTOSOLIC (B) >gi|1403359|emb|CAA67112.1|
(X98486) cytosolic phosphoglycerate kinase [Leishmania
mexicana]
Length = 417
Score = 191 bits (480), Expect = 1e-47
Identities = 132/411 (32%), Positives = 207/411 (50%), Gaps = 32/411 (7%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS 63
+ D +K V +RVD N P+K+G+I +D R R+ LPTI+ +L+ G ++ +H G+P
Sbjct: 9 IDDVALKDKKVLIRVDFNVPVKNGEITNDFRIRSALPTIQKVLKEGGSCILMSHLGRPKG 68
Query: 64 ---------------EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIA 108
E+ AT A LS LL + V D A + +LK G++
Sbjct: 69 ARMSDPKPEKGVRGYEEAATLRPVAARLSELLEEKVAKAPDCLN--ASIYVSKLKRGDVL 126
Query: 109 MLENLRFSAEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPM 168
+LEN+RF EE K E E K L+ D V+DAF AHR ++ G ++
Sbjct: 127 LLENVRFYTEEGSKK---EEEADAMAKVLASYADLYVSDAFGTAHRDSATMTGIPKVLGS 183
Query: 169 -IMGFLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVA 227
G+LME+EI + + P V ++GGAKV D +++ +N+L R + ++ GG +A
Sbjct: 184 GYAGYLMEKEINYFSRVLNNPPRPLVAIVGGAKVSDKIELLDNMLGR--INYLVIGGAMA 241
Query: 228 NVFTLAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIY 287
F A+G +G E K L+L K K E V PVD + + +
Sbjct: 242 YTFQKAQGRKIGISMCEEDK----LDLAKSLLKKAQERGVQVLLPVDHVCNKEFKAVDSP 297
Query: 288 LLSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAI 347
L++E ++ + Y +DIG +TI Y ++I + K + NGPMGVFE + GT V KA+
Sbjct: 298 LVTEDVDVPDGYMALDIGPKTIHMYEEVIGRCKSAIWNGPMGVFEMPCISKGTFAVAKAM 357
Query: 348 A----ESEAFSVLGGGHSIASIQ-KYGIEGITHISTGGGAMLTFFAGEELP 393
+ S++GGG + ++ + + ++H+STGGGA L G+ LP
Sbjct: 358 GTGTQKDGLLSIIGGGDTASAAELSARAKNMSHVSTGGGASLELLEGKTLP 408
>sp|P56154|PGK_HELPY PHOSPHOGLYCERATE KINASE >gi|7434530|pir||A64688 probable
phosphoglycerate kinase (EC 2.7.2.3) - Helicobacter
pylori (strain 26695) >gi|2314511|gb|AAD08386.1|
(AE000635) phosphoglycerate kinase [Helicobacter pylori
26695]
Length = 402
Score = 191 bits (480), Expect = 1e-47
Identities = 125/394 (31%), Positives = 214/394 (53%), Gaps = 22/394 (5%)
Query: 11 NKVVFLRVDLNSPMKDG-KIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPYS-EDYA 67
+K V +RVD N P+ + I D R R LPTI+Y ++N A+ +++ +H G+P E+
Sbjct: 21 HKRVLIRVDFNVPLDENLNITDDTRIRESLPTIQYCIDNKAKDIILVSHLGRPKGVEEKL 80
Query: 68 TTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPIEE 127
+ + + L LLN V + ++I ++ + E P I +LEN+RF E +N
Sbjct: 81 SLKPFLKRLERLLNHEVVFSQNIV--QLKQALNENAPTRIFLLENIRFLRGEEENDEN-- 136
Query: 128 CEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPM-IMGFLMEREIEALMKAYY 186
K L+ + D VNDAF +HR S G A+ P+ + GFL+++EI++ +A+
Sbjct: 137 -----LAKDLASLCDVFVNDAFGTSHRKHASTYGTAKFAPIKVSGFLLKKEIDSFYQAFN 191
Query: 187 SKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRKNIEFM 246
P + ++GGAKV L + +N+L D ++ G ++N F A G+D+ ++E
Sbjct: 192 HPLRPLLLIVGGAKVSSKLTLLKNIL--DLIDKLIIAGAMSNTFLKALGYDVQDSSVEDA 249
Query: 247 KKKGLLELVKHA-EKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQIMDIG 305
LEL++ A EK + + P D ++ K + +S +++ ++I DIG
Sbjct: 250 LINDALELLQSAKEKKVKVYLPIDAVTTDDILNPKHIK-----ISPVQDIEPKHKIADIG 304
Query: 306 SRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGHSIASI 365
+++ + ++I A ++ NGP+GV E++EFA GT + IA++ AFS++GGG +I +I
Sbjct: 305 PASLKLFSEVIESAPTILWNGPLGVHEKQEFARGTTFLAHKIADTYAFSLIGGGDTIDAI 364
Query: 366 QKYG-IEGITHISTGGGAMLTFFAGEELPVLRAL 398
+ G + ++ ISTGGGA L G+ LP L
Sbjct: 365 NRAGEKDNMSFISTGGGASLELLEGKILPCFEVL 398
>pir||D82757 phosphoglycerate kinase XF0823 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9105725|gb|AAF83633.1|AE003922_3
(AE003922) phosphoglycerate kinase [Xylella fastidiosa]
Length = 500
Score = 191 bits (480), Expect = 1e-47
Identities = 132/402 (32%), Positives = 205/402 (50%), Gaps = 24/402 (5%)
Query: 3 RLGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPY 62
R+ D K V +R DLN P+ G+I S+ R A LPTI+ LE GA V+V +H G+P
Sbjct: 114 RMTDLALSGKRVLIRQDLNVPIDQGRITSEQRIIASLPTIRVALERGAAVMVTSHLGRPK 173
Query: 63 SEDYATTEEHARI---LSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE 119
++ + A + LS LL V D ++ PG++ +LEN R + E
Sbjct: 174 EGVWSEEDSLAPVAKRLSQLLGIEVPLRRDWVDGV------QVAPGQLVLLENCRMNVGE 227
Query: 120 VKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGF-LMEREI 178
+N +K + + D V DAF AHR+Q S G + G L+ E+
Sbjct: 228 AENDEA-------LARKYAALCDVFVMDAFGTAHRAQASTHGVICCAAIAAGGPLLMAEL 280
Query: 179 EALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDL 238
+AL + P + ++GG+KV L++ N++ + ++TGG +AN F A G+ +
Sbjct: 281 DALSRGLEHPVKPLLAIVGGSKVSTKLELLSNLVNN--VEQLITGGGIANTFLAAAGYSI 338
Query: 239 GRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLND 298
G+ E + E++ A+ E + P D + + + ++ D
Sbjct: 339 GKSLYEGDLIETAREIITAAKARGAE----IPLPTDVVVAKQFLPGVTATVKTVDAIVAD 394
Query: 299 YQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGG 358
I+DIG +T Y +I A VV NGP+GVFE + F+ GT + +A+A S AFS+ GG
Sbjct: 395 DLILDIGPQTARHYAALIETAATVVWNGPVGVFEFDAFSKGTEVLARAVAASSAFSIAGG 454
Query: 359 GHSIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRALQ 399
G ++A+I KYG+ + I++ISTGGGA L F G+ LP + ALQ
Sbjct: 455 GDTLAAIDKYGVADQISYISTGGGAFLEFLEGKTLPAVAALQ 496
>sp|Q9Z7M5|PGK_CHLPN PHOSPHOGLYCERATE KINASE >gi|7434545|pir||C72049 phosphoglycerate
kinase CP0068 [imported] - Chlamydophila pneumoniae
(strains CWL029 and AR39) >gi|4376980|gb|AAD18818.1|
(AE001650) Phosphoglycerate Kinase [Chlamydophila
pneumoniae CWL029] >gi|7189004|gb|AAF37956.1| (AE002170)
phosphoglycerate kinase [Chlamydophila pneumoniae AR39]
>gi|8979051|dbj|BAA98886.1| (AP002547) phosphoglycerate
kinase [Chlamydophila pneumoniae J138]
Length = 402
Score = 190 bits (479), Expect = 2e-47
Identities = 137/406 (33%), Positives = 201/406 (48%), Gaps = 23/406 (5%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKP---- 61
D + K V +RVD N PM+DGKI+ D R R+ +PTI YLL+ A V++ +H G+P
Sbjct: 8 DLSPEEKKVLVRVDFNVPMQDGKILDDIRIRSAMPTINYLLKKHAAVILMSHLGRPKGQG 67
Query: 62 YSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVK 121
+ E+Y + + +L L HV D G AR+ + +L PG + +LENLRF E
Sbjct: 68 FQEEY-SLQPVVDVLEGYLGHHVPLAPDCVGEVARQAVAQLSPGRVLLLENLRFHIGE-- 124
Query: 122 NKPIEECEK-TFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKP--MIMGFLMEREI 178
E EK F +LS D+ VNDAF +HR S+ + P G LME+E+
Sbjct: 125 ----EHPEKDPTFAAELSSYGDFYVNDAFGTSHRKHASVYVVPQAFPGRAAAGLLMEKEL 180
Query: 179 EALMK-AYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFD 237
E L + S + P +LGGAK+ + V E +L + D +L G + F A G
Sbjct: 181 EFLGRHLLTSPKRPFTAILGGAKISSKIGVIEALLNQ--VDYLLLAGGMGFTFLQALGKS 238
Query: 238 LGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLN 297
LG +E K L+L ++ KI + P D +E ++S + +
Sbjct: 239 LGNSLVE----KSALDLARNVLKIAKSRNVTIVLPSDVKAAENLQSKEYSVISIDQGIPP 294
Query: 298 DYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIA-ESEAFSVL 356
Q DIG RT E++ II ++ V NGP+GV+E F G++ + A+ A +V+
Sbjct: 295 HLQGFDIGPRTTEEFIRIINQSATVFWNGPVGVYEVPPFDSGSIAIANALGNHPSAVTVV 354
Query: 357 GGGHSIASIQKYGIE-GITHISTGGGAMLTFFAGEELPVLRALQIS 401
GGG + A + G ++H+STGGGA L F LP L S
Sbjct: 355 GGGDAAAVVALAGCSTKVSHVSTGGGASLEFLEQGFLPGTEVLSPS 400
>pir||PC1118 phosphoglycerate kinase (EC 2.7.2.3) 1 - tammar wallaby (fragment)
>gi|1150|emb|CAA45574.1| (X64296) phosphoglycerate
kinase [Macropus eugenii]
Length = 416
Score = 190 bits (477), Expect = 3e-47
Identities = 136/404 (33%), Positives = 210/404 (51%), Gaps = 23/404 (5%)
Query: 12 KVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPYS---EDYA 67
K V +RVD N PMK+ +I ++ R +A LP+I Y L+NGA+ VV+ +H G+P D
Sbjct: 16 KRVIMRVDFNVPMKNKEITNNQRIKAALPSINYCLDNGAKSVVLMSHLGRPDGVPMPDKY 75
Query: 68 TTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV-KNKPI- 125
+ E A L +LL + V +++D G + G I +LENLRF EE K K
Sbjct: 76 SLEPVAAELKSLLGKDVLFLKDCVGPEVEQACANPPNGSIILLENLRFHVEEEGKGKDAS 135
Query: 126 ------EECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIE 179
E + F LSK+ D VNDAF AHR+ S+VG + GFLM++E+
Sbjct: 136 GNKIKAEPAKMEAFQASLSKLGDVYVNDAFGTAHRAHSSMVG-VNLPQKACGFLMKKELT 194
Query: 180 ALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLG 239
KA S E P + +LGGAKV D +++ N+L + ++I+ GG+ + ++G
Sbjct: 195 YFAKALDSPERPFLAILGGAKVADKIQLINNMLDK-VNEMIIGGGMGFTFLKVLNNMEIG 253
Query: 240 RKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLSEKRELLND 298
+ K + +L+ AEK + + PVDF K D + + +
Sbjct: 254 TSLFDEEGAKIVKDLMAKAEKNGVK----ITLPVDFVTADKFDENAKTGQATLASGIPAG 309
Query: 299 YQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESE---AFSV 355
+ +D G ++ +KY +++ AK +V NGP+GVFE EEFA GT E+ + E+ ++
Sbjct: 310 WMGLDCGPKSSKKYVEVVTWAKQIVWNGPVGVFEWEEFARGTKELMNNVVEATKRGCITI 369
Query: 356 LGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
+GGG + K+ E ++H+STGGGA L G+ LP + L
Sbjct: 370 IGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVSTL 413
>sp|P29408|PGK1_MACEU PHOSPHOGLYCERATE KINASE 1
Length = 417
Score = 190 bits (477), Expect = 3e-47
Identities = 136/404 (33%), Positives = 210/404 (51%), Gaps = 23/404 (5%)
Query: 12 KVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPYS---EDYA 67
K V +RVD N PMK+ +I ++ R +A LP+I Y L+NGA+ VV+ +H G+P D
Sbjct: 17 KRVIMRVDFNVPMKNKEITNNQRIKAALPSINYCLDNGAKSVVLMSHLGRPDGVPMPDKY 76
Query: 68 TTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV-KNKPI- 125
+ E A L +LL + V +++D G + G I +LENLRF EE K K
Sbjct: 77 SLEPVAAELKSLLGKDVLFLKDCVGPEVEQACANPPNGSIILLENLRFHVEEEGKGKDAS 136
Query: 126 ------EECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIE 179
E + F LSK+ D VNDAF AHR+ S+VG + GFLM++E+
Sbjct: 137 GNKIKAEPAKMEAFQASLSKLGDVYVNDAFGTAHRAHSSMVG-VNLPQKACGFLMKKELT 195
Query: 180 ALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLG 239
KA S E P + +LGGAKV D +++ N+L + ++I+ GG+ + ++G
Sbjct: 196 YFAKALDSPERPFLAILGGAKVADKIQLINNMLDK-VNEMIIGGGMGFTFLKVLNNMEIG 254
Query: 240 RKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLSEKRELLND 298
+ K + +L+ AEK + + PVDF K D + + +
Sbjct: 255 TSLFDEEGAKIVKDLMAKAEKNGVK----ITLPVDFVTADKFDENAKTGQATLASGIPAG 310
Query: 299 YQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESE---AFSV 355
+ +D G ++ +KY +++ AK +V NGP+GVFE EEFA GT E+ + E+ ++
Sbjct: 311 WMGLDCGPKSSKKYVEVVTWAKQIVWNGPVGVFEWEEFARGTKELMNNVVEATKRGCITI 370
Query: 356 LGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
+GGG + K+ E ++H+STGGGA L G+ LP + L
Sbjct: 371 IGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVSTL 414
>sp|Q9ZJP1|PGK_HELPJ PHOSPHOGLYCERATE KINASE >gi|7434548|pir||B71830 phosphoglycerate
kinase - Helicobacter pylori (strain J99)
>gi|4155865|gb|AAD06837.1| (AE001549) PHOSPHOGLYCERATE
KINASE [Helicobacter pylori J99]
Length = 402
Score = 189 bits (476), Expect = 4e-47
Identities = 124/399 (31%), Positives = 216/399 (54%), Gaps = 22/399 (5%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDG-KIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPYS 63
+ + ++K V +RVD N P+ + I D R R LPTI++ ++N A+ +++ +H G+P
Sbjct: 16 EVDVNHKRVLIRVDFNVPLDENLNITDDTRIRESLPTIQFCIDNKAKDIILVSHLGRPKG 75
Query: 64 -EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKN 122
E+ + + + L LLN V + ++I ++ + E P I +LEN+RF E +N
Sbjct: 76 VEEKLSLKPFLKRLERLLNHEVVFSQNI--AQLKQALNENAPTRIFLLENIRFLKGEEEN 133
Query: 123 KPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPM-IMGFLMEREIEAL 181
K L+ + D VNDAF +HR S G A+ P+ + GFL+++EI++
Sbjct: 134 DEN-------LAKDLASLCDVFVNDAFGTSHRKHASTYGTAKFAPIKVSGFLLKKEIDSF 186
Query: 182 MKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLGRK 241
+A+ P + ++GGAKV L + +N+L D ++ G ++N F A G+D+
Sbjct: 187 YQAFNHPLRPLLLIVGGAKVSSKLTLLKNIL--DLIDKLIIAGAMSNTFLKALGYDVQDS 244
Query: 242 NIEFMKKKGLLELVKHA-EKILDEFYPYVRTPVDFAIDYKGDREEIYLLSEKRELLNDYQ 300
++E LEL++ A EK + + P D ++ K + +S +++ ++
Sbjct: 245 SVEDALINDALELLQSAKEKKVKVYLPIDAVTTDDILNPKHIK-----ISPVQDIEPKHK 299
Query: 301 IMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESEAFSVLGGGH 360
I DIG +++ + ++I A ++ NGP+GV E++EFA GT + IA + AFS++GGG
Sbjct: 300 IADIGPASLKLFSEVIESAPTILWNGPLGVHEKQEFARGTTFLAHKIANTYAFSLIGGGD 359
Query: 361 SIASIQKYG-IEGITHISTGGGAMLTFFAGEELPVLRAL 398
+I +I + G + ++ ISTGGGA L G+ LP L
Sbjct: 360 TIDAINRAGEKDNMSFISTGGGASLELLEGKILPCFEVL 398
>sp|P24590|PGK_TRIVI PHOSPHOGLYCERATE KINASE >gi|283403|pir||S25381 phosphoglycerate
kinase (EC 2.7.2.3) - fungus (Trichoderma viride)
Length = 417
Score = 188 bits (472), Expect = 1e-46
Identities = 137/410 (33%), Positives = 210/410 (50%), Gaps = 23/410 (5%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDA-RFRAVLPTIKYLLENGAR-VVVGTHQGKPYS 63
D + K V +RVD N P+ + K I++ R +PTIK+ L+NGA+ V++ +H G+P
Sbjct: 11 DVDVKGKRVLIRVDFNVPLDENKNITNPQRIAGAIPTIKHALDNGAKAVILMSHLGRPNG 70
Query: 64 EDYATTEEHARI--LSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVK 121
A + L LL + V + D G + + G + +LENLRF EE
Sbjct: 71 AVNAKYSLKPVVPKLEELLGKPVTFAPDCVGPEVEAIVNKADNGAVILLENLRFHIEEEG 130
Query: 122 NKPIEECEKTF--------FVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFL 173
+ +E KT F K L+ + D VNDAF AHR+ S+VG + GFL
Sbjct: 131 SSKDKEGNKTKADKAKVEEFRKGLTALGDVYVNDAFGTAHRAHSSMVG-VDLPQKAAGFL 189
Query: 174 MEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLA 233
M++E++ KA S + P + +LGGAKV D +++ +N+L + +I+ GG+ FT
Sbjct: 190 MKKELDYFAKALESPQRPFLAILGGAKVSDKIQLIDNLLDK-VNTLIICGGMA---FTFK 245
Query: 234 KGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLSEK 292
K D K G + K EK + V P DF K D++ L ++K
Sbjct: 246 KVLDNLAIGDSLFDKAGAETVPKLVEKAKAKNVKIV-LPTDFITADKFDKDANTGLATDK 304
Query: 293 RELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAE--- 349
+ + + +D G +I+ Y++ I +AK ++ NGP GVFE E+FA GT A+ E
Sbjct: 305 DGIPDGWMGLDCGDESIKLYKEAIDEAKTILWNGPAGVFEFEKFAGGTKATLDAVVEGCK 364
Query: 350 SEAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
+ ++GGG + KYG+E ++H+STGGGA L G+ELP + AL
Sbjct: 365 NGKIVIIGGGDTATVAAKYGVEDKLSHVSTGGGASLELLEGKELPGVTAL 414
>pir||KIHOG phosphoglycerate kinase (EC 2.7.2.3) - horse
Length = 416
Score = 187 bits (471), Expect = 2e-46
Identities = 137/413 (33%), Positives = 213/413 (51%), Gaps = 25/413 (6%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGK-- 60
L N K V +RVD N PMK+ +I ++ R +A +P+IK+ L+NGA+ VV+ +H G+
Sbjct: 8 LDKLNVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPD 67
Query: 61 -PYSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE 119
P D + + A L +LL + V +++D G + + G + +LENLRF EE
Sbjct: 68 GPVMPDKYSLQPVAVELKSLLGKDVLFLKDCVGPEVEKACADPAAGSVILLENLRFHVEE 127
Query: 120 V-KNK-------PIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMG 171
K K E + F LSK+ D VNDAF AHR+ S+VG + G
Sbjct: 128 EGKGKDASGNKVKAEPAKIETFRASLSKLGDVYVNDAFGTAHRAHSSMVG-VNLPQKAGG 186
Query: 172 FLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFT 231
FLM++E+ KA S E P + +LGGAKV D +++ N+L + ++I+ GG+
Sbjct: 187 FLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDK-VNEMIIGGGMAFTFLK 245
Query: 232 LAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLS 290
+ ++G + K + L+ AEK + + PVDF K D + +
Sbjct: 246 VLNNMEIGTSLFDEEGAKIVKNLMSKAEKNGVK----ITLPVDFVTADKFDEHAKTGQAT 301
Query: 291 EKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTV----EVFKA 346
+ + +D G+ + +KY + + +AK +V NGP+GVFE E FA GT EV KA
Sbjct: 302 VASGIPAGWMGLDCGTESSKKYAEAVARAKQIVWNGPVGVFEWEAFARGTKALMDEVVKA 361
Query: 347 IAESEAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
+ +++GGG + K+ E ++H+STGGGA L G+ LP + AL
Sbjct: 362 TSRG-CITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDAL 413
>gb|AAA39921.1| (M18654) testis-specific phosphoglycerate kinase [Mus musculus]
Length = 417
Score = 187 bits (471), Expect = 2e-46
Identities = 135/405 (33%), Positives = 213/405 (52%), Gaps = 25/405 (6%)
Query: 12 KVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPYS---EDYA 67
K V +RVD N PMK+ +I ++ R +A +P+IK+ L+NGA+ VV+ +H G+P D
Sbjct: 17 KRVIMRVDFNVPMKNNQITNNQRIKAAIPSIKHCLDNGAKSVVLMSHLGRPDGIPMPDKY 76
Query: 68 TTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEV------- 120
+ E A L +LLN+ V +++D G + G I +LENLRF EE
Sbjct: 77 SLEPVADELKSLLNKDVIFLKDCVGPEVEQACANPDNGSIILLENLRFHVEEEGKGKDSS 136
Query: 121 -KNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIE 179
K + + F LSK+ D VNDAF AHR+ S+VG + GFLM++E++
Sbjct: 137 GKKISADPAKVEAFQASLSKLGDVYVNDAFGTAHRAHSSMVG-VNLPQKASGFLMKKELD 195
Query: 180 ALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLG 239
KA E P + +LGGAKV D +++ +N+L + +I+ GG+ K +G
Sbjct: 196 YFSKALEKPERPFLAILGGAKVKDKIQLIKNMLDK-VNFMIIGGGMAYTFLKELKNMQIG 254
Query: 240 RKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLSEKRELLND 298
+ + E+++ AEK + + PVDF K D ++ + + + +
Sbjct: 255 ASLFDEEGATIVKEIMEKAEKNGVK----IVFPVDFVTGDKFDENAKVGQATIESGIPSG 310
Query: 299 YQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTV----EVFKAIAESEAFS 354
+ +D G +I+ I+ +AK++V NGP+GVFE + FA GT EV KA + +
Sbjct: 311 WMGLDCGPESIKINAQIVAQAKLIVWNGPIGVFEWDAFAKGTKALMDEVVKATSNG-CVT 369
Query: 355 VLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
++GGG + K+G E ++H+STGGGA L G+ LP + AL
Sbjct: 370 IIGGGDTATCCAKWGTEDKVSHVSTGGGASLELLEGKILPGVEAL 414
>sp|P00559|PGK_HORSE PHOSPHOGLYCERATE KINASE
Length = 416
Score = 187 bits (469), Expect = 3e-46
Identities = 137/413 (33%), Positives = 213/413 (51%), Gaps = 25/413 (6%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKP- 61
L N K V +RVD N PMK+ +I ++ R +A +P+IK+ L+NGA+ VV+ +H G+P
Sbjct: 8 LDKLNVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPD 67
Query: 62 --YSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE 119
D + + A L +LL + V +++D G + + G + +LENLRF EE
Sbjct: 68 VGPMPDKYSLQPVAVELKSLLGKDVLFLKDCVGPEVEKACADPAAGSVILLENLRFHVEE 127
Query: 120 V-KNK-------PIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMG 171
K K E + F LSK+ D VNDAF AHR+ S+VG + G
Sbjct: 128 EGKGKDASGNKVKAEPAKIETFRASLSKLGDVYVNDAFGTAHRAHSSMVG-VNLPQKAGG 186
Query: 172 FLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFT 231
FLM++E+ KA S E P + +LGGAKV D +++ N+L + ++I+ GG+
Sbjct: 187 FLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDK-VNEMIIGGGMAFTFLK 245
Query: 232 LAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLS 290
+ ++G + K + L+ AEK + + PVDF K D + +
Sbjct: 246 VLNNMEIGTSLFDEEGAKIVKNLMSKAEKNGVK----ITLPVDFVTADKFDENAKTGQAT 301
Query: 291 EKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTV----EVFKA 346
+ + +D G+ + +KY + + +AK +V NGP+GVFE E FA GT EV KA
Sbjct: 302 VASGIPAGWMGLDCGTESSKKYAEAVARAKQIVWNGPVGVFEWEAFARGTKALMDEVVKA 361
Query: 347 IAESEAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
+ +++GGG + K+ E ++H+STGGGA L G+ LP + AL
Sbjct: 362 TSRG-CITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDAL 413
>gi|4505763 phosphoglycerate kinase 1 [Homo sapiens] >gi|2144428|pir||KIHUG
phosphoglycerate kinase (EC 2.7.2.3) - human
>gi|35435|emb|CAA23835.1| (V00572) coding sequence [Homo
sapiens] >gi|387020|gb|AAA60078.1| (L00160)
phosphoglycerate kinase (EC 2.7.2.3) [Homo sapiens]
>gi|387021|gb|AAA60079.1| (M11968) phosphoglycerate
kinase [Homo sapiens]
Length = 417
Score = 185 bits (466), Expect = 6e-46
Identities = 137/413 (33%), Positives = 212/413 (51%), Gaps = 25/413 (6%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPY 62
L + K V +RVD N PMK+ +I ++ R +A +P+IK+ L+NGA+ VV+ +H G+P
Sbjct: 9 LDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPD 68
Query: 63 S---EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE 119
D + E A L +LL + V +++D G + G + +LENLRF EE
Sbjct: 69 GVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEE 128
Query: 120 V-KNK-------PIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMG 171
K K E + F LSK+ D VNDAF AHR+ S+VG + G
Sbjct: 129 EGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVG-VNLPQKAGG 187
Query: 172 FLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFT 231
FLM++E+ KA S E P + +LGGAKV D +++ N+L + ++I+ GG+
Sbjct: 188 FLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDK-VNEMIIGGGMAFTFLK 246
Query: 232 LAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLS 290
+ ++G + K + +L+ AEK + + PVDF K D + +
Sbjct: 247 VLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVK----ITLPVDFVTADKFDENAKTGQAT 302
Query: 291 EKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTV----EVFKA 346
+ + +D G + +KY + + +AK +V NGP+GVFE E FA GT EV KA
Sbjct: 303 VASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKA 362
Query: 347 IAESEAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
+ +++GGG + K+ E ++H+STGGGA L G+ LP + AL
Sbjct: 363 TSRG-CITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDAL 414
>pir||A24830 phosphoglycerate kinase (EC 2.7.2.3) - Emericella nidulans
Length = 421
Score = 185 bits (466), Expect = 6e-46
Identities = 130/413 (31%), Positives = 211/413 (50%), Gaps = 27/413 (6%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGK---IISDARFRAVLPTIKYLLENGAR-VVVGTHQGKP 61
D + +K V +RVD N P+ I + R LPTIKY ++NGA+ V++ +H G+P
Sbjct: 11 DVDLKDKRVLIRVDFNVPLDKNDNTTITNPQRIVGALPTIKYAIDNGAKAVILMSHLGRP 70
Query: 62 YSEDYATTEEHARI--LSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE 119
+ + L LL + V + ED G E + + G++ +LENLRF AEE
Sbjct: 71 DGKKNPKYSLKPVVPKLKELLGRDVIFTEDCVGPEVEETVNKASGGQVILLENLRFHAEE 130
Query: 120 VKNKPIEECEKTF--------FVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMG 171
+ + K F K L+ + D +NDAF AHR+ S+VG + G
Sbjct: 131 EGSSKDADGNKVKADKDAVAQFRKGLTALGDITINDAFGTAHRAHSSMVG-VDLPQKASG 189
Query: 172 FLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFT 231
FL+++E+E KA + P + +LGG+KV D +++ +N+L + +I+TGG+
Sbjct: 190 FLVKKELEYFAKALEEPQRPFLAILGGSKVSDKIQLIDNLLPK-VNSLIITGGMAFTFKK 248
Query: 232 LAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDF--AIDYKGDREEIYLL 289
+ +G + K + +++ A+K V PVD+ A + D + Y
Sbjct: 249 TLENVKIGSSLFDEAGSKIVGNIIEKAKK----HNVKVVLPVDYVTADKFAADAKTGYAT 304
Query: 290 SEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFA---LGTVEVFKA 346
E+ + + Y +D+G +++E Y+ I ++K ++ NGP GVFE E FA T++ A
Sbjct: 305 DEQG-IPDGYMGLDVGEKSVESYKQTIAESKTILWNGPPGVFEMEPFAKATKATLDAAVA 363
Query: 347 IAESEAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
++ A ++GGG + KYG E I+H+STGGGA L G+ELP + AL
Sbjct: 364 AVQNGATVIIGGGDTATVAAKYGAEDKISHVSTGGGASLELLEGKELPGVAAL 416
>sp|P00558|PGK1_HUMAN PHOSPHOGLYCERATE KINASE 1 (PRIMER RECOGNITION PROTEIN 2) (PRP 2)
Length = 418
Score = 185 bits (466), Expect = 6e-46
Identities = 137/413 (33%), Positives = 212/413 (51%), Gaps = 25/413 (6%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPY 62
L + K V +RVD N PMK+ +I ++ R +A +P+IK+ L+NGA+ VV+ +H G+P
Sbjct: 9 LDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPD 68
Query: 63 S---EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE 119
D + E A L +LL + V +++D G + G + +LENLRF EE
Sbjct: 69 GVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEE 128
Query: 120 V-KNK-------PIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMG 171
K K E + F LSK+ D VNDAF AHR+ S+VG + G
Sbjct: 129 EGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVG-VNLPQKAGG 187
Query: 172 FLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFT 231
FLM++E+ KA S E P + +LGGAKV D +++ N+L + ++I+ GG+
Sbjct: 188 FLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDK-VNEMIIGGGMAFTFLK 246
Query: 232 LAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLS 290
+ ++G + K + +L+ AEK + + PVDF K D + +
Sbjct: 247 VLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVK----ITLPVDFVTADKFDENAKTGQAT 302
Query: 291 EKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTV----EVFKA 346
+ + +D G + +KY + + +AK +V NGP+GVFE E FA GT EV KA
Sbjct: 303 VASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKA 362
Query: 347 IAESEAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
+ +++GGG + K+ E ++H+STGGGA L G+ LP + AL
Sbjct: 363 TSRG-CITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDAL 414
>sp|P50310|PGK_CRIGR PHOSPHOGLYCERATE KINASE >gi|2117894|pir||I48074 phosphoglycerate
kinase (EC 2.7.2.3) - Chinese hamster
>gi|987048|emb|CAA86028.1| (Z37974) phosphoglycerate
kinase [Cricetulus griseus]
Length = 417
Score = 185 bits (466), Expect = 6e-46
Identities = 137/413 (33%), Positives = 212/413 (51%), Gaps = 25/413 (6%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPY 62
L + K V +RVD N PMK+ +I ++ R +A +P+IK+ L+NGA+ VV+ +H G+P
Sbjct: 9 LDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPD 68
Query: 63 S---EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE 119
D + E A L +LL + V +++D G G + +LENLRF EE
Sbjct: 69 GVPMPDKYSLEPVAAELKSLLGKDVLFLKDCVGPEVENACANPAAGTVILLENLRFHVEE 128
Query: 120 V-KNK-------PIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMG 171
K K E + F LSK+ D VNDAF AHR+ S+VG + G
Sbjct: 129 EGKGKDASGNKIKAEPAKIDAFRASLSKLGDVYVNDAFGTAHRAHSSMVG-VNLPQKAGG 187
Query: 172 FLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFT 231
FLM++E+ KA S E P + +LGGAKV D +++ N+L + ++I+ GG+
Sbjct: 188 FLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDK-VNEMIIGGGMAFTFLK 246
Query: 232 LAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLS 290
+ ++G + K + +L+ AEK + + PVDF K D + +
Sbjct: 247 VLNNMEIGTSLYDEEGAKIVKDLMAKAEKNGVK----ITLPVDFVTADKFDENAKTGQAT 302
Query: 291 EKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTV----EVFKA 346
+ + +D G+ + +KY + + +AK +V NGP+GVFE E FA GT EV KA
Sbjct: 303 VASGIPAGWMGLDCGTESSKKYAEAVARAKQIVWNGPVGVFEWEAFARGTKSLMDEVVKA 362
Query: 347 IAESEAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
+ +++GGG + K+ E ++H+STGGGA L G+ LP + AL
Sbjct: 363 TSRG-CITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDAL 414
>gi|11419710 phosphoglycerate kinase 1 [Homo sapiens]
Length = 443
Score = 185 bits (466), Expect = 6e-46
Identities = 137/413 (33%), Positives = 212/413 (51%), Gaps = 25/413 (6%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPY 62
L + K V +RVD N PMK+ +I ++ R +A +P+IK+ L+NGA+ VV+ +H G+P
Sbjct: 35 LDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPD 94
Query: 63 S---EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE 119
D + E A L +LL + V +++D G + G + +LENLRF EE
Sbjct: 95 GVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEE 154
Query: 120 V-KNK-------PIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMG 171
K K E + F LSK+ D VNDAF AHR+ S+VG + G
Sbjct: 155 EGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVG-VNLPQKAGG 213
Query: 172 FLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFT 231
FLM++E+ KA S E P + +LGGAKV D +++ N+L + ++I+ GG+
Sbjct: 214 FLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDK-VNEMIIGGGMAFTFLK 272
Query: 232 LAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLS 290
+ ++G + K + +L+ AEK + + PVDF K D + +
Sbjct: 273 VLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVK----ITLPVDFVTADKFDENAKTGQAT 328
Query: 291 EKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTV----EVFKA 346
+ + +D G + +KY + + +AK +V NGP+GVFE E FA GT EV KA
Sbjct: 329 VASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKA 388
Query: 347 IAESEAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
+ +++GGG + K+ E ++H+STGGGA L G+ LP + AL
Sbjct: 389 TSRG-CITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDAL 440
>sp|P16617|PGK2_RAT PHOSPHOGLYCERATE KINASE, TESTIS SPECIFIC >gi|112127|pir||A33792
phosphoglycerate kinase (EC 2.7.2.3) - rat
>gi|206113|gb|AAA41838.1| (M31788) phosphoglycerate
kinase [Rattus norvegicus]
Length = 417
Score = 185 bits (465), Expect = 8e-46
Identities = 137/413 (33%), Positives = 211/413 (50%), Gaps = 25/413 (6%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPY 62
L + K V +RVD N PMK+ +I ++ R +A +P+IK+ L+NGA VV+ +H G+P
Sbjct: 9 LDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGANSVVLMSHLGRPD 68
Query: 63 S---EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE 119
D + E A L +LL + V +++D G G + +LENLRF EE
Sbjct: 69 GVPMPDKYSLEPVAAELKSLLGKDVLFLKDCVGSEVENACANPAAGTVILLENLRFHVEE 128
Query: 120 V-KNK-------PIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMG 171
K K E + F LSK+ D VNDAF AHR+ S+VG + G
Sbjct: 129 EGKGKDASGNKVKAEPAKIDAFRASLSKLGDVYVNDAFGTAHRAHSSMVG-VNLPQKAGG 187
Query: 172 FLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFT 231
FLM++E+ KA S E P + +LGGAKV D +++ N+L + ++I+ GG+
Sbjct: 188 FLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDK-VNEMIIGGGMAFTFLK 246
Query: 232 LAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLS 290
+ ++G + K + +L+ AEK + + PVDF K D + +
Sbjct: 247 VLNNMEIGTSLYDEEGAKIVKDLMTKAEKNGVK----ITLPVDFVTADKFDENAKTGQAT 302
Query: 291 EKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTV----EVFKA 346
+ + +D G+ + +KY + + +AK +V NGP+GVFE E FA GT EV KA
Sbjct: 303 VASGIPAGWMGLDCGTESSKKYAEAVARAKQIVWNGPVGVFEWEAFARGTKSLMDEVVKA 362
Query: 347 IAESEAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
+ +++GGG + K+ E ++H+STGGGA L G+ LP + AL
Sbjct: 363 TSRG-CITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDAL 414
>sp|P11977|PGK_EMENI PHOSPHOGLYCERATE KINASE >gi|168070|gb|AAA33318.1| (M27549)
3-phosphoglycerate kinase (PGK) [Aspergillus nidulans]
Length = 421
Score = 185 bits (465), Expect = 8e-46
Identities = 130/413 (31%), Positives = 211/413 (50%), Gaps = 27/413 (6%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGK---IISDARFRAVLPTIKYLLENGAR-VVVGTHQGKP 61
D + +K V +RVD N P+ I + R LPTIKY ++NGA+ V++ +H G+P
Sbjct: 11 DVDLKDKRVLIRVDFNVPLDKNDNTTITNPQRIVGALPTIKYAIDNGAKAVILMSHLGRP 70
Query: 62 YSEDYATTEEHARI--LSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE 119
+ + L LL + V + ED G E + + G++ +LENLRF AEE
Sbjct: 71 DGKKNPKYSLKPVVPKLKELLGRDVIFTEDCVGPEVEETVNKASGGQVILLENLRFHAEE 130
Query: 120 VKNKPIEECEKTF--------FVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMG 171
+ + K F K L+ + D +NDAF AHR+ S+VG + G
Sbjct: 131 EGSSKDADGNKVKADKDAVAQFRKGLTALGDIYINDAFGTAHRAHSSMVG-VDLPQKASG 189
Query: 172 FLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFT 231
FL+++E+E KA + P + +LGG+KV D +++ +N+L + +I+TGG+
Sbjct: 190 FLVKKELEYFAKALEEPQRPFLAILGGSKVSDKIQLIDNLLPK-VNSLIITGGMAFTFKK 248
Query: 232 LAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDF--AIDYKGDREEIYLL 289
+ +G + K + +++ A+K V PVD+ A + D + Y
Sbjct: 249 TLENVKIGSSLFDEAGSKIVGNIIEKAKK----HNVKVVLPVDYVTADKFAADAKTGYAT 304
Query: 290 SEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFA---LGTVEVFKA 346
E+ + + Y +D+G +++E Y+ I ++K ++ NGP GVFE E FA T++ A
Sbjct: 305 DEQG-IPDGYMGLDVGEKSVESYKQTIAESKTILWNGPPGVFEMEPFAKATKATLDAAVA 363
Query: 347 IAESEAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
++ A ++GGG + KYG E I+H+STGGGA L G+ELP + AL
Sbjct: 364 AVQNGATVIIGGGDTATVAAKYGAEDKISHVSTGGGASLELLEGKELPGVAAL 416
>sp|O02608|PGK_EUPCR PHOSPHOGLYCERATE KINASE >gi|2109276|gb|AAB58162.1| (U97355)
phosphoglycerate kinase [Euplotes crassus]
Length = 418
Score = 185 bits (465), Expect = 8e-46
Identities = 132/406 (32%), Positives = 210/406 (51%), Gaps = 26/406 (6%)
Query: 11 NKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKP--YSEDYA 67
NK V +RVD N P+KDGK+ R + L TI +L ENGA+ +V+ +H G+P ++
Sbjct: 17 NKRVLVRVDFNVPIKDGKVADPTRIVSTLDTINFLKENGAKSIVLMSHLGRPKGVRQEQF 76
Query: 68 TTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKNKPIEE 127
+ L +++ Q V ++ D G ++ K G I +LENLRF EE + K +
Sbjct: 77 SLAPVVPALEDIIGQKVNFLNDCIGTEVEGEVANTKDGNILLLENLRFYLEE-EGKGVIN 135
Query: 128 CEKT--------FFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGFLMEREIE 179
EK F +L+++ D VNDAF HR+ S+VG + GFL+++E++
Sbjct: 136 GEKVKADPTKVESFRSQLTRLGDLYVNDAFGTCHRAHSSMVG-VNVDTRAAGFLLKKELD 194
Query: 180 ALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLG 239
K + P +LGGAKV D +++ N+L AD ++ GG +A FT K +
Sbjct: 195 YFSKVLEDPKRPLTVILGGAKVADKIQLINNLL--DLADEMIIGGGMA--FTFNKVLNNT 250
Query: 240 RKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDF--AIDYKGDREEIYLLSEKRELLN 297
++G + EK ++ + P DF A + D + Y L K E +
Sbjct: 251 PIGASLYDEEGAKTVHGIMEKAKEKGVK-IHIPSDFVCAESFAEDAKFAYKLKMK-ESQD 308
Query: 298 DYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESE---AFS 354
+ +DIG +TI + ++I ++ + NGP GVFE + FA G+ + +A+ ES S
Sbjct: 309 GWLGLDIGDKTIRSFDEVIRRSNTLFWNGPSGVFEWKNFAKGSHAMLQAVTESTKNGTVS 368
Query: 355 VLGGGHSIASIQKY--GIEGITHISTGGGAMLTFFAGEELPVLRAL 398
V GGG ++ +++ E I+H+STGGGA L G+ELP ++AL
Sbjct: 369 VCGGGDTLNLLKQVDGAKENISHVSTGGGASLELVEGKELPGIKAL 414
>gi|6679291 phosphoglycerate kinase 1 [Mus musculus]
>gi|129903|sp|P09411|PGK1_MOUSE PHOSPHOGLYCERATE KINASE
1 >gi|91176|pir||A25567 phosphoglycerate kinase (EC
2.7.2.3) - mouse >gi|202423|gb|AAA70267.1| (M15668)
phosphoglycerate kinase [Mus musculus]
Length = 417
Score = 184 bits (463), Expect = 1e-45
Identities = 137/413 (33%), Positives = 211/413 (50%), Gaps = 25/413 (6%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPY 62
L + K V +RVD N PMK+ +I ++ R +A +P+IK+ L+NGA VV+ +H G+P
Sbjct: 9 LDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGANSVVLMSHLGRPD 68
Query: 63 S---EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE 119
D + E A L +LL + V +++D G G + +LENLRF EE
Sbjct: 69 GVPMPDKYSLEPVAAELKSLLGKDVLFLKDCVGPEVENACANPAAGTVILLENLRFHVEE 128
Query: 120 V-KNK-------PIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMG 171
K K E + F LSK+ D VNDAF AHR+ S+VG + G
Sbjct: 129 EGKGKDASGNKVKAEPAKIDAFRASLSKLGDVYVNDAFGTAHRAHSSMVG-VNLPQKAGG 187
Query: 172 FLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFT 231
FLM++E+ KA S E P + +LGGAKV D +++ N+L + ++I+ GG+
Sbjct: 188 FLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDK-VNEMIIGGGMAFTFLK 246
Query: 232 LAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLS 290
+ ++G + K + +L+ AEK + + PVDF K D + +
Sbjct: 247 VLNNMEIGTSLYDEEGAKIVKDLMSKAEKNGVK----ITLPVDFVTADKFDENAKTGQAT 302
Query: 291 EKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTV----EVFKA 346
+ + +D G+ + +KY + + +AK +V NGP+GVFE E FA GT EV KA
Sbjct: 303 VASGIPAGWMGLDCGTESSKKYAEAVGRAKQIVWNGPVGVFEWEAFARGTKSLMDEVVKA 362
Query: 347 IAESEAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
+ +++GGG + K+ E ++H+STGGGA L G+ LP + AL
Sbjct: 363 TSRG-CITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDAL 414
>sp|O83549|PGK_TREPA PHOSPHOGLYCERATE KINASE >gi|7434533|pir||G71311 probable
phosphoglycerate kinase (pgk) - syphilis spirochete
>gi|3322829|gb|AAC65523.1| (AE001229) phosphoglycerate
kinase (pgk) [Treponema pallidum]
Length = 419
Score = 182 bits (458), Expect = 5e-45
Identities = 140/427 (32%), Positives = 214/427 (49%), Gaps = 49/427 (11%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKP--- 61
D + V +RVD N PM+DG + D R A +PT++Y++E G R VV+ +H G P
Sbjct: 8 DVTMRGERVVVRVDFNVPMRDGMVQDDTRVTAAVPTLRYIIEQGPRHVVLISHLGDPTRD 67
Query: 62 -------YSEDYATTEEHARI------------LSNLLNQHVEYVEDIFGRYAREKIQEL 102
+D + HA I L+ L V + G+ RE I+ L
Sbjct: 68 ADKAEGNAKKDGCPFDRHAFINGKHRLKPVADCLAKKLGVPVHFAPSCVGQ--REFIEGL 125
Query: 103 KPGEIAMLENLRFSAEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGF 162
G + +LEN+RF EE + + F ++L++ D VNDAF AHR S V
Sbjct: 126 PDGSVVLLENVRFHPEETSG---DAKVQEQFARELAQYGDIFVNDAFGTAHREHASTVVL 182
Query: 163 ARI-KPMIMGFLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVIL 221
R+ + + G L+ERE+ L + + P V V+GGAKV + V E++LR A ++
Sbjct: 183 PRLMRRRVAGLLIEREVRYLEPMVCNPKVPMVAVVGGAKVSSKIAVLESLLRTSTA--LI 240
Query: 222 TGGLVANVFTLAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYP---YVRTPVDF--A 276
GG +A F A+G +G +E + + A +L + V PVD A
Sbjct: 241 IGGGMAYTFLKAQGVGVGTSLVED-------DFIDTARMLLQKAQSGGVSVVLPVDHVCA 293
Query: 277 IDYKGDREEIYLLSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEF 336
+ D + + + + + MD+G RT+E+YR + V+ NGP+GVFE + F
Sbjct: 294 STFCADAQPVAV--DDVHIPMHLMGMDVGPRTLEQYRAHLKGVSSVLWNGPVGVFEFDAF 351
Query: 337 ALGTVEVFKAIAESE---AFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEEL 392
A GT + + IAE+ A SV+GGG SIA++ K+G+ ++H+STGGGA L F G+ L
Sbjct: 352 AHGTRVLAQLIAEATDAGATSVVGGGDSIAAVSKFGLASRMSHVSTGGGASLKLFEGKVL 411
Query: 393 PVLRALQ 399
P + L+
Sbjct: 412 PGISCLE 418
>sp|P38667|PGK_NEUCR PHOSPHOGLYCERATE KINASE >gi|11260667|pir||T43864 phosphoglycerate
kinase (EC 2.7.2.3) [imported] - Neurospora crassa
>gi|3052|emb|CAA39865.1| (X56512) phosphoglycerate
kinase [Neurospora crassa]
Length = 418
Score = 182 bits (457), Expect = 7e-45
Identities = 133/415 (32%), Positives = 208/415 (50%), Gaps = 33/415 (7%)
Query: 6 DFNYHNKVVFLRVDLNSPMK-DGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKP-- 61
D + K V +RVD N P+ + K+ + R +PTIKY L++GA+ VV+ +H G+P
Sbjct: 11 DVDLKGKRVLIRVDFNVPLDAEKKVTNPQRIAGAIPTIKYALDHGAKAVVLMSHLGRPDR 70
Query: 62 -----YSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFS 116
YS E L LL + V + D G E + + GE+ +LENLRF
Sbjct: 71 KPNPKYSLKPVVPE-----LEKLLGKKVTFAPDCVGPEVEEIVNKADNGEVILLENLRFH 125
Query: 117 AEEVKNKPIEECEKTF--------FVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPM 168
EE E K F K L+K+ D +NDAF AHR+ S+VG +
Sbjct: 126 IEEEGKGTDAEGNKVKADKAKVEEFRKNLTKLGDVYINDAFGTAHRAHSSMVGID-LPVK 184
Query: 169 IMGFLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVAN 228
GFLM++E++ K S + P + +LGGAKV D +++ +N+L + +I+ GG+
Sbjct: 185 AAGFLMKKELQYFAKVLESPQRPFLSILGGAKVSDKIQLIDNLLDK-VNTLIVCGGMAFT 243
Query: 229 VFTLAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIY 287
+ +G + K + +LVK AEK + PVDF I K D++
Sbjct: 244 FKKTLQNMPIGNSLFDEAGAKIVPDLVKKAEKNNVKLV----LPVDFTIADKFDKDANTG 299
Query: 288 LLSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKA- 346
++K + + + +D G +++ + I +++ ++ NGP GVFE ++FA GT A
Sbjct: 300 YATDKDGIPDGWMGLDCGEESVKLFTQAINESQTILWNGPAGVFEFDKFAKGTKATLDAC 359
Query: 347 --IAESEAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
AE ++GGG + KYG+E ++H+STGGGA L G+ LP + AL
Sbjct: 360 VKAAEEGRTVIIGGGDTATVAAKYGVEDKLSHVSTGGGASLELLEGKALPGVVAL 414
>gb|AAF73528.1| (AE002274) phosphoglycerate kinase [Chlamydia muridarum]
Length = 403
Score = 181 bits (455), Expect = 1e-44
Identities = 130/397 (32%), Positives = 199/397 (49%), Gaps = 20/397 (5%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYSED 65
D + K V +RVD N P+KDGKI+ D R R+ +PTI YLL+ A +++ +H G+P +
Sbjct: 8 DLSPEGKKVLVRVDFNVPIKDGKILDDVRIRSAMPTINYLLKRDAAIILVSHLGRPKGDM 67
Query: 66 YATTEEHARI---LSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKN 122
+ A I L L HV D G AR+ + +L PG + +LEN+RF E
Sbjct: 68 FEEAYSLAPIVPVLEGYLGHHVPLSPDCVGEVARQAVAQLSPGRVLLLENVRFHRGEEHP 127
Query: 123 KPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKP--MIMGFLMEREIEA 180
+ E F +L+ D+ VNDAF +HR S+ ++ P GFLME+E+E
Sbjct: 128 E-----EDPSFAVELAAYADFYVNDAFGTSHRKHASVYRVPQMFPDRAAAGFLMEKELEF 182
Query: 181 L-MKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLG 239
L + P +LGGAKV + V E +L R +++L GG+ F A +G
Sbjct: 183 LGQHLLVEPKRPFTAILGGAKVSSKIGVIEALLSR-VDNLVLAGGM-GYTFLKAMNQQVG 240
Query: 240 RKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDR-EEIYLLSEKRELLND 298
+E + G+ + EK + + PVD + + + E+ LS + +
Sbjct: 241 NSLVE---ETGIPLAKRVLEKARTQGVK-IYLPVDAKVARRCETGEDWQELSIQEGIPEG 296
Query: 299 YQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIA-ESEAFSVLG 357
+ DIGS+TI + ++I + V NGP+GV+E F G+ + + +A S A +V+G
Sbjct: 297 FSGFDIGSKTIALFSEVIQDSATVFWNGPVGVYEVPPFDQGSKAIAQCLASHSSAVTVVG 356
Query: 358 GGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELP 393
GG + A + G I+H+STGGGA L F LP
Sbjct: 357 GGDAAAVVALAGCTSQISHVSTGGGASLEFLEKGYLP 393
>gb|AAB41227.1| (U83197) 3-phosphoglycerate kinase [Chlamydia trachomatis]
Length = 405
Score = 180 bits (451), Expect = 3e-44
Identities = 129/400 (32%), Positives = 200/400 (49%), Gaps = 26/400 (6%)
Query: 6 DFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS-- 63
D + K V +RVD N P+KDGKI+ D R R+ +PTI YLL+ A V++ +H G+P
Sbjct: 10 DLSLEGKKVLVRVDFNVPIKDGKILDDVRIRSAMPTIHYLLKQDAAVILVSHLGRPKGGV 69
Query: 64 -EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEEVKN 122
E+ + +L L HV D G AR+ + +L PG + +LEN+RF E
Sbjct: 70 FEEAYSLAPIVPVLEGYLGHHVPLSPDCIGEVARQAVAQLSPGRVLLLENVRFHKGE--E 127
Query: 123 KPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKP--MIMGFLMEREIEA 180
P E+ F +L+ D+ VNDAF +HR S+ ++ P GFLME+E+E
Sbjct: 128 HPDED---PSFAIELAAYADFYVNDAFGTSHRKHASVYRVPQLFPDRAAAGFLMEKELEF 184
Query: 181 L-MKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGFDLG 239
L + P +LGGAK+ + V E +L D ++ G + F A +G
Sbjct: 185 LGQHLLVEPKRPFTAILGGAKMSSKIGVIEALL--SCVDHLVLAGGMGYTFLRAMNRQVG 242
Query: 240 RKNIEFMKKKGLLELVKHAEKILDEFYPY---VRTPVDFAIDYKGDREEIYL-LSEKREL 295
+E + G + A+K+L++ + PVD + + D E + LS + +
Sbjct: 243 NSLVE---ESG----IPLAKKVLEKAQALGVKIHLPVDAKVAKQCDSGEDWRELSIQEGI 295
Query: 296 LNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIA-ESEAFS 354
DIG++TIE + +I ++ + NGP+GV+E F G+ + + +A S A +
Sbjct: 296 PEGLAGFDIGAQTIELFSKVIQESATIFWNGPVGVYEVPPFDQGSKAIAQCLASHSSAVT 355
Query: 355 VLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELP 393
V+GGG + A + G I+H+STGGGA L F LP
Sbjct: 356 VVGGGDAAAVVALAGCTSQISHVSTGGGASLEFLEKGSLP 395
>emb|CAB61501.1| (AL049589) dJ570L12.1 (phosphoglycerate kinase 1) [Homo sapiens]
Length = 410
Score = 179 bits (450), Expect = 4e-44
Identities = 135/409 (33%), Positives = 209/409 (51%), Gaps = 28/409 (6%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPY 62
L + K V +RVD N PMK+ +I ++ R +A +P+IK+ L+NGA+ VV+ +H G+P
Sbjct: 9 LDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPD 68
Query: 63 S---EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE 119
D + E A L +LL + V +++D G + G + +LENLRF EE
Sbjct: 69 GVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEE 128
Query: 120 V-KNK-------PIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMG 171
K K E + F LSK+ D VNDAF AHR+ S+VG + G
Sbjct: 129 EGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVG-VNLPQKAGG 187
Query: 172 FLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFT 231
FLM++E+ KA S E P + +LGGAKV D +++ N+L + ++I+ GG+
Sbjct: 188 FLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDK-VNEMIIGGGMAFTFLK 246
Query: 232 LAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLLS 290
+ ++G + K + +L+ AEK + + PVDF K D + +
Sbjct: 247 VLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVK----ITLPVDFVTADKFDENAKTGQAT 302
Query: 291 EKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTV----EVFKA 346
+ + +D G + +KY + + +AK +V NGP+GVFE E FA GT EV KA
Sbjct: 303 VASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKA 362
Query: 347 IAESEAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPV 394
+ +++GGG + K+ E ++H+STGGGA L E+PV
Sbjct: 363 TSRG-CITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELL---EVPV 407
>sp|P07205|PGK2_HUMAN PHOSPHOGLYCERATE KINASE, TESTIS SPECIFIC >gi|88344|pir||A27816
phosphoglycerate kinase (EC 2.7.2.3) 2 - human
>gi|35438|emb|CAA28872.1| (X05246) PGK (AA 1-417) [Homo
sapiens] >gi|225539|prf||1305347A
kinase,phosphoglycerate [Homo sapiens]
Length = 417
Score = 179 bits (449), Expect = 6e-44
Identities = 128/414 (30%), Positives = 209/414 (49%), Gaps = 27/414 (6%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVV-----GTHQ 58
L + K V +RVD N PMK +I ++ R +A +P+IKY L+NGA+ VV G
Sbjct: 9 LDKLDVRGKRVIMRVDFNVPMKKNQITNNQRIKASIPSIKYCLDNGAKAVVLMSHLGRPD 68
Query: 59 GKPYSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAE 118
G P + Y+ A L +LL + V +++D G + PG + +LENLRF E
Sbjct: 69 GVPMPDKYSLAPV-AVELKSLLGKDVLFLKDCVGAEVEKACANPAPGSVILLENLRFHVE 127
Query: 119 EV--------KNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIM 170
E K E + F LSK+ D VNDAF AHR+ S+VG +
Sbjct: 128 EEGKGQDPSGKKIKAEPDKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVG-VNLPHKAS 186
Query: 171 GFLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVF 230
GFLM++E++ KA + P + +LGGAKV D +++ +N+L + ++I+ GG+
Sbjct: 187 GFLMKKELDYFAKALENPVRPFLAILGGAKVADKIQLIKNMLDK-VNEMIIGGGMAYTFL 245
Query: 231 TLAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLL 289
+ ++G + K + +++ A+K + PVDF K D ++
Sbjct: 246 KVLNNMEIGASLFDEEGAKIVKDIMAKAQK----NGVRITFPVDFVTGDKFDENAQVGKA 301
Query: 290 SEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTV----EVFK 345
+ + + +D G + + + ++ +A+++V NGP+GVFE + FA GT E+ K
Sbjct: 302 TVASGISPGWMGLDCGPESNKNHAQVVAQARLIVWNGPLGVFEWDAFAKGTKALMDEIVK 361
Query: 346 AIAESEAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
A ++ +V+GGG + K+ E ++H+STG GA L G+ LP + AL
Sbjct: 362 ATSKG-CITVIGGGDTATCCAKWNTEDKVSHVSTGRGASLELLEGKILPGVEAL 414
>sp|P50311|PGK_OPISI PHOSPHOGLYCERATE KINASE >gi|4204091|gb|AAD10200.1| (L47982)
phosphoglycerate kinase [Clonorchis sinensis]
Length = 415
Score = 175 bits (439), Expect = 9e-43
Identities = 128/419 (30%), Positives = 207/419 (48%), Gaps = 38/419 (9%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPY 62
+ + + +K V +RVD N PMKDGK+ + R PTIKY L+ GA+ +V+ +H G
Sbjct: 8 IANVDLKDKRVLMRVDFNVPMKDGKVTNTQRIVGASPTIKYALDKGAKSIVLMSHLGGRV 67
Query: 63 SEDYA--TTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAEE- 119
A + +S LL + V+++ D G E + + G + +LENLRF EE
Sbjct: 68 GNKVARYSLNPVGEEVSKLLGKPVKFLPDCVGPETTEGMCQSSAGSVFLLENLRFHVEEE 127
Query: 120 --------VKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMG 171
K K E K F + L+K+ D +NDAF AHR+ S+VG R+ G
Sbjct: 128 GKGVSPTGEKIKATPEQVKA-FSENLTKLGDVYLNDAFGTAHRAHASMVG-CRLTQRACG 185
Query: 172 FLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFT 231
FLM++E+ K + P + ++GGAKV D +++ +N+L + ++I+TGG+
Sbjct: 186 FLMDKELTYFSKLLDQPQHPFLAIIGGAKVSDKIQLIKNMLDK-VDELIITGGMAFTFLK 244
Query: 232 LAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRT-------PVDFAI-DYKGDR 283
+G+ + + I+DE+ ++ PVDF D +
Sbjct: 245 KLHNMKIGKSLYD-----------EPGAAIVDEWMQLAKSKNVKIHLPVDFITGDKFAED 293
Query: 284 EEIYLLSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEV 343
+ + + + + +D G +T+E++ +I +AK +V NGPMGVFE E+FA GT
Sbjct: 294 ANTGTATVEPGIRDTHMGLDGGPKTMEEFCKVISRAKTIVWNGPMGVFEMEKFAGGTKAA 353
Query: 344 FKAIAESEAFSVL---GGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
A+ + V GGG + K+ E ++H+STG GA L G++LP + AL
Sbjct: 354 MDAVVAATTKGVTNNNGGGDTATCCPKWKTEAQVSHVSTGVGASLELLEGKQLPGILAL 412
>sp|O61471|PGK_APLCA PHOSPHOGLYCERATE KINASE >gi|3043929|gb|AAC13267.1| (AF042738)
phosphoglycerate kinase [Aplysia californica]
Length = 412
Score = 175 bits (438), Expect = 1e-42
Identities = 127/414 (30%), Positives = 207/414 (49%), Gaps = 29/414 (7%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGAR-VVVGTHQGKPY 62
+ D + +K V +RVD N P+K+G+I ++ R A LPTIK LE GA+ VV+ +H G+P
Sbjct: 6 INDVDVRDKRVLIRVDFNVPLKNGQISNNQRIAAALPTIKLALEKGAKSVVLMSHLGRPD 65
Query: 63 SEDY--ATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAE-E 119
A+ + L NLL + + ++ED G +PG + +LENLRF E E
Sbjct: 66 GRPIHAASMKPVVAELENLLGKKIMFLEDCVGSKVEAACANPEPGSVILLENLRFHVEKE 125
Query: 120 VKNK-------PIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIMGF 172
K K ++ F LSK+ D VNDAF AHR+ S+VG + G
Sbjct: 126 GKGKDAQGNKAKADDAAVAAFRASLSKLGDVYVNDAFGTAHRAHSSMVG-VDLPVKACGL 184
Query: 173 LMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTL 232
LM++E++ KA + P + +LGGAKV D +++ EN++ + ++I+ GG+ +
Sbjct: 185 LMKKELDYFAKALENPARPFLAILGGAKVADKIQLIENLMDK-VNEMIIGGGMAFTFLKV 243
Query: 233 AKGFDLGRKNIEFMKKKGLLELVKHAEKILD---EFYPYVRTPVDFAI-DYKGDREEIYL 288
D+G + E K +++D E + P DF D D +
Sbjct: 244 LNNMDIGGSLFD--------EGAKIVGRLVDKAKEKGVKLHLPSDFITGDKFADVAKSAT 295
Query: 289 LSEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAI- 347
S + + +D+G++T E ++ +I AK +V NGP GVFE E F+ G+ ++ ++
Sbjct: 296 ASVASGIPEGWMGLDVGTKTNEVFQKVIEGAKTIVWNGPPGVFEFENFSTGSKQMMDSVV 355
Query: 348 --AESEAFSVLGG-GHSIASIQKYGIEGITHISTGGGAMLTFFAGEELPVLRAL 398
E+ +++GG + + E ++H+STG G L G+ LP + AL
Sbjct: 356 RATEAGTITIIGGCDTATCAKNSNATEKVSHVSTGSGTSLELLEGKILPGVAAL 409
>prf||1107228A kinase,phosphoglycerate [Homo sapiens]
Length = 417
Score = 173 bits (433), Expect = 4e-42
Identities = 125/414 (30%), Positives = 207/414 (49%), Gaps = 27/414 (6%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVV-----GTHQ 58
L + K V +RVD N PMK +I ++ R +A +P+IKY L+NGA+ VV G
Sbjct: 9 LDKLDVRGKRVIMRVDFNVPMKKNQITNNQRIKASIPSIKYCLDNGAKAVVLMSHLGRPD 68
Query: 59 GKPYSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSAE 118
G P + Y+ A L +LL + V +++D G + PG + +LENLRF E
Sbjct: 69 GVPMPDKYSLAPV-AVELKSLLGKDVLFLKDCVGAEVEKACANPAPGSVILLENLRFHVE 127
Query: 119 EV--------KNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARIKPMIM 170
E K E + F LSK+ D VNDAF AHR+ S+VG +
Sbjct: 128 EEGKGQDPSGKKIKAEPDKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVG-VNLPHKAS 186
Query: 171 GFLMEREIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVF 230
GFLM++E++ KA + P + +LGGAKV D +++ +N+L + ++I+ GG++
Sbjct: 187 GFLMKKELDYFAKALENPVRPFLAILGGAKVADKIQLIKNMLDK-VNEMIIGGGMLITFL 245
Query: 231 TLAKGFDLGRKNIEFMKKKGLLELVKHAEKILDEFYPYVRTPVDFAIDYKGDRE-EIYLL 289
+ ++G + K + +++ A+K + PVDF K D ++
Sbjct: 246 KVLNNMEIGASLFDEEGAKIVKDIMAKAQK----NGVRITFPVDFVTGDKFDENAQVGKA 301
Query: 290 SEKRELLNDYQIMDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTV----EVFK 345
+ + + +D G + + + ++ +A+++V NGP+ FE + FA GT E+ K
Sbjct: 302 TVASGISPGWMGLDCGPESNKNHAQVVAQARLIVWNGPLEXFEWDAFAKGTKALMDEIVK 361
Query: 346 AIAESEAFSVLGGGHSIASIQKYGIEG-ITHISTGGGAMLTFFAGEELPVLRAL 398
A ++ +V+GGG + K+ E ++H+ST GA L G+ LP + AL
Sbjct: 362 ATSKG-CITVIGGGDTATCCAKWNTEDKVSHVSTXSGASLELLEGKILPGVEAL 414
>gb|AAF02830.1|AC009894_1 (AC009894) phosphoglycerate kinase [Arabidopsis thaliana]
Length = 320
Score = 148 bits (371), Expect = 8e-35
Identities = 91/248 (36%), Positives = 138/248 (54%), Gaps = 17/248 (6%)
Query: 4 LGDFN---YHNKVVFLRVDLNSPMKDGK-IISDARFRAVLPTIKYLLENGARVVVGTHQG 59
+GD N K VF+R DLN P+ D + I D R RA +PTIK+L+ENGA+V++ TH G
Sbjct: 79 VGDLNSVDLKGKKVFVRADLNVPLDDNQNITDDTRIRAAIPTIKFLIENGAKVILSTHLG 138
Query: 60 KP--YSEDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPGEIAMLENLRFSA 117
+P + ++ R LS LL V +D G + L G + +LEN+RF
Sbjct: 139 RPKGVTPKFSLAPLVPR-LSELLGIEVVKADDCIGPEVETLVASLPEGGVLLLENVRFYK 197
Query: 118 EEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFAR-IKPMIMGFLMER 176
EE KN+P F KKL+ + D VNDAF AHR+ S G + +KP + GFL+++
Sbjct: 198 EEEKNEP-------DFAKKLASLADLYVNDAFGTAHRAHASTEGVTKFLKPSVAGFLLQK 250
Query: 177 EIEALMKAYYSKESPRVYVLGGAKVDDSLKVAENVLRRGFADVILTGGLVANVFTLAKGF 236
E++ L+ A + + P ++GG+KV + V E++L + D++L GG + F A+G
Sbjct: 251 ELDYLVGAVSNPKRPFAAIVGGSKVSSKIGVIESLLEK--CDILLLGGGMIFTFYKAQGL 308
Query: 237 DLGRKNIE 244
+G +E
Sbjct: 309 SVGSSLVE 316
>gb|AAC37223.1| (L37337) phosphoglycerate kinase [Trypanosoma congolense]
Length = 215
Score = 94.8 bits (232), Expect = 2e-18
Identities = 63/212 (29%), Positives = 102/212 (47%), Gaps = 24/212 (11%)
Query: 4 LGDFNYHNKVVFLRVDLNSPMKDGKIISDARFRAVLPTIKYLLENGARVVVGTHQGKPYS 63
+ + + K +RVD N P+K G I +D R R+ LPTI+ +L G ++ +H G+P
Sbjct: 9 INECDLKGKKTLVRVDFNVPVKGGVITNDYRIRSALPTIQKVLNEGGSCILMSHLGRPKG 68
Query: 64 ------------------EDYATTEEHARILSNLLNQHVEYVEDIFGRYAREKIQELKPG 105
E+ AT A+ L LL++ V + D A + ++++ PG
Sbjct: 69 ISISEAAAVRSAGKVPGYEEAATLRPVAQRLGELLSKPVVFAPDCLD--AADVVKKMSPG 126
Query: 106 EIAMLENLRFSAEEVKNKPIEECEKTFFVKKLSKVIDYVVNDAFAAAHRSQPSLVGFARI 165
++ +LEN+RF EE K E E+ K L+ D V+DAF AHR ++ G ++
Sbjct: 127 DVVLLENVRFYREEGSKK---EEEREAMAKVLASYGDIFVSDAFGTAHRDSATMTGIPKV 183
Query: 166 KPM-IMGFLMEREIEALMKAYYSKESPRVYVL 196
G+LME+EI K + P V ++
Sbjct: 184 LGHGAAGYLMEKEISYFSKVLGNPPRPLVAIV 215
>gb|AAA03386.1| (U02234) Homology to phosphoglycerate kinase X54519 [Mycoplasma
genitalium]
Length = 101
Score = 78.4 bits (190), Expect = 1e-13
Identities = 42/100 (42%), Positives = 65/100 (65%), Gaps = 2/100 (2%)
Query: 302 MDIGSRTIEKYRDIIMKAKVVVANGPMGVFEREEFALGTVEVFKAIAESE-AFSVLGGGH 360
+D+GS+TI + + AK + NGP+GVFE FA GT ++ + IA+++ AFSV+GGG
Sbjct: 1 LDVGSKTIALFESYLKTAKTIFWNGPLGVFEFTNFAKGTSKIGEIIAKNKTAFSVIGGGD 60
Query: 361 SIASIQKYGI-EGITHISTGGGAMLTFFAGEELPVLRALQ 399
S A++++ + + + ISTGGGA L GEEL + +Q
Sbjct: 61 SAAAVKQMQLSDQFSFISTGGGASLALIGGEELVGISDIQ 100
>gb|AAB36526.1| (U76418) 3-phosphoglycerate kinase [Neisseria gonorrhoeae]
Length = 76
Score = 69.1 bits (166), Expect = 9e-11
Identities = 34/67 (50%), Positives = 51/67 (75%), Gaps = 1/67 (1%)
Query: 334 EEFALGTVEVFKAIAESEAFSVLGGGHSIASIQKYGI-EGITHISTGGGAMLTFFAGEEL 392
++FA GT + +AIA+S+AFS+ GGG ++A+I K+G+ + I +ISTGGGA L F G+EL
Sbjct: 1 DQFAGGTKALAEAIAQSKAFSIAGGGDTLAAIAKFGVTDQIGYISTGGGAFLEFLEGKEL 60
Query: 393 PVLRALQ 399
P + AL+
Sbjct: 61 PAVAALE 67
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.321 0.139 0.388
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 143652810
Number of Sequences: 2977
Number of extensions: 5935333
Number of successful extensions: 16984
Number of sequences better than 1.0e-10: 177
Number of HSP's better than 0.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 136
Number of HSP's that attempted gapping in prelim test: 15970
Number of HSP's gapped (non-prelim): 186
length of query: 410
length of database: 189,106,746
effective HSP length: 58
effective length of query: 352
effective length of database: 154,394,500
effective search space: 54346864000
effective search space used: 54346864000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 166 (69.1 bits)