BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1704 (PAB1704) DE:MEMBRANE PROTEIN (264 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||A75076 membrane protein PAB1704 - Pyrococcus abyssi (strain... 505 e-142 pir||E72257 hypothetical protein TM1404 - Thermotoga maritima (s... 89 4e-17 pir||C72492 probable membrane protein APE2578 - Aeropyrum pernix... 86 4e-16 pir||D75108 daunorubicin resistance membrane protein (drrb) PAB1... 84 1e-15 gi|11499467 daunorubicin resistance membrane protein (drrB) [Arc... 82 9e-15 gb|AAK42314.1| Membrane conserved hypothetical protein [Sulfolob... 81 1e-14 emb|CAC11999.1| (AL445065) conserved hypothetical membrane prote... 80 3e-14 pir||A71081 hypothetical protein PH0911 - Pyrococcus horikoshii ... 79 5e-14 pir||S32909 hypothetical protein 5 - Streptomyces antibioticus >... 74 2e-12 pir||T50567 probable ABC-type transport protein, transmembrane c... 73 3e-12 pir||S74047 hypothetical protein c0111 - Sulfolobus solfataricus... 73 5e-12 >pir||A75076 membrane protein PAB1704 - Pyrococcus abyssi (strain Orsay) >gi|5458422|emb|CAB49910.1| (AJ248286) MEMBRANE PROTEIN [Pyrococcus abyssi] Length = 264 Score = 505 bits (1286), Expect = e-142 Identities = 264/264 (100%), Positives = 264/264 (100%) Query: 1 MTMMVNAINSFKVAISRETKIGIDLEFLLGTLFEPMIYVLLFGPLMGKLIGDLEVNGMRI 60 MTMMVNAINSFKVAISRETKIGIDLEFLLGTLFEPMIYVLLFGPLMGKLIGDLEVNGMRI Sbjct: 1 MTMMVNAINSFKVAISRETKIGIDLEFLLGTLFEPMIYVLLFGPLMGKLIGDLEVNGMRI 60 Query: 61 SYLAFMFPGVLTLVSINQGFRGATTFIQDRFYGGLETLFTLPVPRTVLFMAKILSACIRA 120 SYLAFMFPGVLTLVSINQGFRGATTFIQDRFYGGLETLFTLPVPRTVLFMAKILSACIRA Sbjct: 61 SYLAFMFPGVLTLVSINQGFRGATTFIQDRFYGGLETLFTLPVPRTVLFMAKILSACIRA 120 Query: 121 IIAMIVLSILTLIIAKDASITLTGFIGSLLVNSLLVVMLSSFMIYLLSKSQNPNLPLAIS 180 IIAMIVLSILTLIIAKDASITLTGFIGSLLVNSLLVVMLSSFMIYLLSKSQNPNLPLAIS Sbjct: 121 IIAMIVLSILTLIIAKDASITLTGFIGSLLVNSLLVVMLSSFMIYLLSKSQNPNLPLAIS 180 Query: 181 GIVILPMMFLSTVFYPETVFESSKVLSILVSINPMTHASNLVRSFIYGTHLQHSTMVVSL 240 GIVILPMMFLSTVFYPETVFESSKVLSILVSINPMTHASNLVRSFIYGTHLQHSTMVVSL Sbjct: 181 GIVILPMMFLSTVFYPETVFESSKVLSILVSINPMTHASNLVRSFIYGTHLQHSTMVVSL 240 Query: 241 AYLLVLAFIGMLIGLRGFKAALEK 264 AYLLVLAFIGMLIGLRGFKAALEK Sbjct: 241 AYLLVLAFIGMLIGLRGFKAALEK 264 >pir||E72257 hypothetical protein TM1404 - Thermotoga maritima (strain MSB8) >gi|4981968|gb|AAD36475.1|AE001793_5 (AE001793) antibiotic ABC transporter, transmembrane protein, putative [Thermotoga maritima] Length = 256 Score = 89.3 bits (218), Expect = 4e-17 Identities = 52/236 (22%), Positives = 114/236 (48%), Gaps = 6/236 (2%) Query: 28 LLGTLFEPMIYVLLFGPLMGKLIGDLEVNGM--RISYLAFMFPGVLTLVSINQGFRGATT 85 ++G + P+I+++ FG K+ + M + YL ++ PG+ + N F + Sbjct: 22 VIGMIINPLIWIIFFGLGWSKVFDNPWAKMMFGGVDYLTYLAPGIFAMTVFNMSFISGVS 81 Query: 86 FIQDRFYGGLETLFTLPVPRTVLFMAKILSACIRAIIAMIVLSILTLIIAKDASITLTGF 145 I D+ +G + + P R + +I+ I ++ +++ + +A+ S+ ++G Sbjct: 82 LIWDKQFGFFKEVLVAPSSRRLSITGRIVGDAIVTVLQGLIILVFNYFLAE--SLKISGL 139 Query: 146 IGSLLVNSLLVVMLSSFMIYLLSKSQNPNLPLAISGIVILPMMFLSTVFYPETVFESSKV 205 + +L V L+ V ++SF I L K ++ I +++P++FLS YP + Sbjct: 140 LPALAVGFLMSVTIASFGIALALKMESTEGFQMIMMTLMMPLVFLSGAMYP--IDSMPNW 197 Query: 206 LSILVSINPMTHASNLVRSFIYGTHLQHSTMVVSLAYLLVLAFIGMLIGLRGFKAA 261 + L INP+T+A + R ++ G + + + L +L +G+++ + F+ A Sbjct: 198 MKALAYINPLTYAVDASRGYLVGEKVMKFSFGLDWGILSILMLVGLILAMESFERA 253 >pir||C72492 probable membrane protein APE2578 - Aeropyrum pernix (strain K1) >gi|5106284|dbj|BAA81595.1| (AP000064) 283aa long hypothetical membrane protein [Aeropyrum pernix] Length = 283 Score = 86.2 bits (210), Expect = 4e-16 Identities = 60/206 (29%), Positives = 106/206 (51%), Gaps = 10/206 (4%) Query: 62 YLAFMFPGVLTLVSINQGFRGATTFIQDRFYGGLETLFTLPVPRTVLFMAKILSACIR-A 120 Y ++ G+L + S+ Q GA + DR G L L P+PR +F +K+L R Sbjct: 82 YFTYVATGMLAVFSLFQSMFGAVGVVFDRRIGYLTRLLASPIPRFSIFASKVLGTLFRIT 141 Query: 121 IIAMIVLSI-LTLIIAKDASITLTGFIGSLLVNSLLVVMLSSFMIYLLSKSQNPNLPLAI 179 ++++I+L+I L + IT+ + + LV L+ + LSS + + + A+ Sbjct: 142 VLSLILLAIAYPLGLHLKPGITIIDLVMAWLVLMLMSLGLSSLFTGMAFNITHQEVLFAL 201 Query: 180 SGIVILPMMFLSTVFYPETVFESSKVLSILVSINPMTHASNLVRSFIYGTHLQHSTMVVS 239 + ++ LP+MF S+ +P + + L + +NP+THA++LVR ++ G L+ V+S Sbjct: 202 ANLINLPLMFSSSALFPIDLMPN--WLKTVAQVNPITHAADLVRYYLVGKPLEDP--VMS 257 Query: 240 LAYLLVLAFI----GMLIGLRGFKAA 261 +AYL VL G + + G K A Sbjct: 258 IAYLAVLTLFLLAAGYTLAINGVKEA 283 >pir||D75108 daunorubicin resistance membrane protein (drrb) PAB1924 - Pyrococcus abyssi (strain Orsay) >gi|5458092|emb|CAB49581.1| (AJ248285) daunorubicin resistance membrane protein (drrB) [Pyrococcus abyssi] Length = 257 Score = 84.3 bits (205), Expect = 1e-15 Identities = 58/230 (25%), Positives = 111/230 (48%), Gaps = 14/230 (6%) Query: 28 LLGTLFEPMIYVLLFGPLMGKLIGDLEVNGMR-----ISYLAFMFPGVLTLVSINQGFRG 82 +LG+L P+I+++ FG G G + + Y+ ++ PG++ + N GF Sbjct: 25 VLGSLLNPLIWLIFFGKGWA---GAFNFPGAKMIFGGVDYMTYLVPGIVAMTVFNMGFMQ 81 Query: 83 ATTFIQDRFYGGLETLFTLPVPRTVLFMAKILSACIRAIIAMIVLSILTLIIAKDASITL 142 T I DR +G L+ L P R + + + + A+I ++ L+ + A + L Sbjct: 82 GITLIWDRQFGFLKELLVAPASRVEAIIGRSIGGALMALIQGTIILALSFTL---ADLKL 138 Query: 143 TGFIGSLLVNSLLVVMLSSFMIYLLSKSQNPNLPLAISGIVILPMMFLSTVFYPETVFES 202 +G + +LL+ L+ + +S + + + + I +++LPM FLS FYP + Sbjct: 139 SGVVPTLLLAFLVGIAVSGMGMAIAMRMTSMEGFQIIVTMLMLPMTFLSGAFYP--ISTM 196 Query: 203 SKVLSILVSINPMTHASNLVRSFIYGTHLQHSTMV-VSLAYLLVLAFIGM 251 K + L INP+T+A + R ++ G + S + + LL + F+G+ Sbjct: 197 PKWMQYLAKINPLTYAVDGARYYLAGINPTFSLAIDWGVLSLLAVIFVGI 246 >gi|11499467 daunorubicin resistance membrane protein (drrB) [Archaeoglobus fulgidus] >gi|7483281|pir||B69485 daunorubicin resistance membrane protein (drrB) homolog - Archaeoglobus fulgidus >gi|2648660|gb|AAB89369.1| (AE000972) daunorubicin resistance membrane protein (drrB) [Archaeoglobus fulgidus] Length = 251 Score = 81.5 bits (198), Expect = 9e-15 Identities = 57/249 (22%), Positives = 119/249 (46%), Gaps = 10/249 (4%) Query: 8 INSFKVAISRETKIGIDLEF-LLGTLFEPMIYVLLFGPLMGKLIGDLEVNGMRISYLAFM 66 + +F++ + R+ K + + G + P++++ FG + D + G + YL ++ Sbjct: 1 MRAFEIMVYRQIKRFLRARSRVAGMIINPLVWLTFFGIGWSRAFRDPSIFG-GVDYLTYL 59 Query: 67 FPGVLTLVSINQGFRGATTFIQDRFYGGLETLFTLPVPRTVLFMAKILSACIRAIIAMIV 126 PG+ + NQ F + I DR +G L+ + P R +I A + + Sbjct: 60 SPGIFAMTVFNQSFVSGISVIWDREFGFLKEVLVAPASRKETIAGRIFGDSAVATLQGAI 119 Query: 127 LSILTLIIAKDASITLTGFIGSLLVNSLLVVMLSSFMIYLLSKSQNPNLPLAISGIVILP 186 + LT IA+ I + G I +L V +L V SSF + + ++ ++ I +V+LP Sbjct: 120 ILALTFFIAR---INIFGVIPALGVGFVLAVAFSSFGVSIAARMRSMEGFQMIMALVMLP 176 Query: 187 MMFLSTVFYPETVFESSKVLSILVSINPMTHA---SNLVRSFIYGTHLQHSTMVVSLAYL 243 ++FLS YP + + +L +NP+T+A S ++ + + G ++++ L+ Sbjct: 177 LIFLSGAIYPIAFMPA--WMKVLALLNPLTYAVESSRVLLTGVSGIFPLDQSLLILLSLT 234 Query: 244 LVLAFIGML 252 ++ ++ M+ Sbjct: 235 ALMLYVAMV 243 >gb|AAK42314.1| Membrane conserved hypothetical protein [Sulfolobus solfataricus] Length = 290 Score = 81.1 bits (197), Expect = 1e-14 Identities = 66/254 (25%), Positives = 118/254 (45%), Gaps = 31/254 (12%) Query: 28 LLGTLFEPMIYVLLFGPLM--GKLIGDLEVN--------------GMRI--------SYL 63 LL +L +P+ ++ +FG M G + + N G+ I Y Sbjct: 33 LLLSLIQPIFWIGIFGKAMNLGSIFTETTFNIPGLTIPKQVLDQIGLEILKQTFGTTDYF 92 Query: 64 AFMFPGVLTLVSINQGFRGATTFIQDRFYGGLETLFTLPVPRTVLFMAKILSACIRAII- 122 +F+ G+L+ + + + + + DR G L+ + T PVPR + + K+LSA IR+++ Sbjct: 93 SFLAAGMLSFIVLFTSMQSGMSIVWDRRLGVLDRILTTPVPRGNIIIGKVLSAVIRSLVQ 152 Query: 123 AMIVLSILTLI-IAKDASITLTGFIGSLLVNSLLVVMLSSFMIYLLSKSQNPNLPLAISG 181 A IVL + L+ + I F+G L+ LSS + L ++ + +AI Sbjct: 153 ATIVLVVAVLLGMTFAPEINPLDFLGVYAALFLMSFGLSSLFLMLALRATSWESQMAIMN 212 Query: 182 IVILPMMFLSTVFYPETVFESSKVLSILVSINPMTHASNLVRSFIYGTHLQHSTMVVSLA 241 ++ LP++F S FYP V L + INP+T+++ + R + G + + + Sbjct: 213 LLNLPLLFTSNAFYP--VKSMPYWLKPVAYINPLTYSNGVARGMLLGI---STNLAIDFL 267 Query: 242 YLLVLAFIGMLIGL 255 YL + A I IG+ Sbjct: 268 YLGLFAIILSTIGI 281 >emb|CAC11999.1| (AL445065) conserved hypothetical membrane protein [Thermoplasma acidophilum] Length = 267 Score = 80.0 bits (194), Expect = 3e-14 Identities = 60/240 (25%), Positives = 118/240 (49%), Gaps = 17/240 (7%) Query: 27 FLLGTLFEPMIYVLLFGPLM------GKLIGDLEVNGMRISYLAFMFPGVLTLVSINQGF 80 +L+ L +P+ +++LFG G + +G + Y+ +M G+LT+ + G Sbjct: 21 YLIVGLLQPVFWIILFGSAFDIAKFGGPFVSSF-FDGAK-DYITYMIGGILTITGLFTGM 78 Query: 81 RGATTFIQDRFYGGLETLFTLPVPRTVLFMAKILSACIRAIIAMIVLSILTLIIAKDASI 140 I DR G L+ P+ R+ + ++I+++ +R I+ +++L + LII I Sbjct: 79 FSGINIIWDRRLGILQRFLVSPIKRSSIVFSRIIASVVRIIVQVVILVAIALIIPDGLKI 138 Query: 141 TLTGFI--GSLLVNSLLVV--MLSSFMIYLLSKSQNPNLPLAISGIVILPMMFLSTVFYP 196 + + I L++ ++L++ + SS + + + I+ +V LP+MF S +P Sbjct: 139 SSSFTIEDAFLMIAAVLMISFIFSSIFSIIAIRMTRMETIMGITNLVNLPLMFASYALFP 198 Query: 197 ETVFESSKVLSILVSINPMTHASNLVR-SFIYG--THLQHSTMVVSLAYLLVLAFIGMLI 253 + S LS + NP++ ++ +R IYG T Q ST V + YL +L + +L+ Sbjct: 199 PDLMVS--WLSTVAKYNPVSWSAESIRLLIIYGNLTGSQMSTFVSYMLYLFILTVVMILL 256 >pir||A71081 hypothetical protein PH0911 - Pyrococcus horikoshii >gi|3257324|dbj|BAA30007.1| (AP000004) 257aa long hypothetical protein [Pyrococcus horikoshii] Length = 257 Score = 79.2 bits (192), Expect = 5e-14 Identities = 63/265 (23%), Positives = 121/265 (44%), Gaps = 22/265 (8%) Query: 8 INSFKVAISRETKIGI-DLEFLLGTLFEPMIYVLLFG---------PLMGKLIGDLEVNG 57 +N F I RE K I ++G++ P+++++ FG P+ ++ G ++ Sbjct: 4 MNVFLTMIYRELKRFIRSPSRIIGSILNPLLWLIFFGKGWSGVFNFPMATRIFGGVD--- 60 Query: 58 MRISYLAFMFPGVLTLVSINQGFRGATTFIQDRFYGGLETLFTLPVPRTVLFMAKILSAC 117 Y+ ++ PGV+ + + F T I D+ +G ++ + P R + +I Sbjct: 61 ----YMTYLVPGVVVMTVFDMSFLQGLTIIWDKQFGFMKEILVAPASRVESILGRITGGA 116 Query: 118 IRAIIAMIVLSILTLIIAKDASITLTGFIGSLLVNSLLVVMLSSFMIYLLSKSQNPNLPL 177 I A+I ++ L+ I+A ++ ++G I +L++ + V ++ + + K + Sbjct: 117 IVAMIQGFIMVALSFIVA---NLKVSGVIPTLILAFFVGVAIAGLGVAVALKMSSMEGFQ 173 Query: 178 AISGIVILPMMFLSTVFYPETVFESSKVLSILVSINPMTHASNLVRSFIYGTHLQHSTMV 237 I +++LPMMFLS FYP V + L INP+T+A + R ++ G M Sbjct: 174 IIVMMLMLPMMFLSGAFYP--VRTMPNWMQWLAKINPLTYAVDGARYYLAGVTPTFGIMQ 231 Query: 238 VSLAYLLVLAFIGMLIGLRGFKAAL 262 + +L+ GL KA L Sbjct: 232 DWIVLILLALVFAGFAGLEFRKAYL 256 >pir||S32909 hypothetical protein 5 - Streptomyces antibioticus >gi|153383|gb|AAA26794.1| (L06249) membrane protein [Streptomyces antibioticus] Length = 273 Score = 73.7 bits (178), Expect = 2e-12 Identities = 55/227 (24%), Positives = 109/227 (47%), Gaps = 7/227 (3%) Query: 24 DLEFLLGTLFEPMIYVLLFGPLMGKLIGDLEVNGMRISYLAFMFPGVLTLVSINQGFRGA 83 D E + + P+++ LLF + G IG + G + Y+ ++ PG+L ++ +N Sbjct: 40 DPESMFDAILFPVVFTLLFVYVFGGSIGK-SLGGGQEQYVQYVVPGLLAMMGMNMAQGVG 98 Query: 84 TTFIQDRFYGGLETLFTLPVPRTVLFMAKILSACIRAIIAMIVLSILTLIIAKDASITLT 143 T F QD G ++ +LP+ R + AKI +R + A VL ++ L++ + + L Sbjct: 99 TGFNQDFNSGVMDRFRSLPIGRGSVLFAKIAVELMRMLFATAVLLVVALLVGYEVGM-LE 157 Query: 144 GFIGSLLVNSLLVVMLSSFMIYLLSKSQNPNLPLAISGIVILPMMFLSTVFYPETVFESS 203 +GS+ +++L L + L +N A+ +V++P+ F S++F P Sbjct: 158 RLLGSVALSALFGSALMWVFLTLGVVMKNAQSVQAMGFLVLMPLQFGSSIFAPTQSMPG- 216 Query: 204 KVLSILVSINPMTHASNLVRSFIYGTHLQHS---TMVVSLAYLLVLA 247 L NP++ ++ R + G + H+ T++ S+ +V+A Sbjct: 217 -WLQAFTDYNPLSALADCARGLMEGGPVAHALWVTVIWSVGLTVVMA 262 >pir||T50567 probable ABC-type transport protein, transmembrane component [imported] - Streptomyces coelicolor >gi|6469243|emb|CAB61704.1| (AL133220) probable ABC-transporter, transmembrane component. [Streptomyces coelicolor A3(2)] Length = 274 Score = 73.4 bits (177), Expect = 3e-12 Identities = 58/239 (24%), Positives = 111/239 (46%), Gaps = 11/239 (4%) Query: 24 DLEFLLGTLFEPMIYVLLFGPLMGKLIGDLEVNGMRISYLAFMFPGVLTLVSINQGFRGA 83 D E + + P+++ LLF + G IG + G + +Y+ ++ PG++ ++ +N Sbjct: 41 DPESMFDAILFPIVFTLLFVYVFGGSIGQ-SLGGGQQAYVQYVIPGLMAMMGMNMAQGVG 99 Query: 84 TTFIQDRFYGGLETLFTLPVPRTVLFMAKILSACIRAIIAMIVLSILTLIIAKDASITLT 143 T F QD G ++ +LP+ R + AKI +R + A VL ++ +++ D +T Sbjct: 100 TGFNQDFNSGVMDRFRSLPIGRGSVLFAKIAVELLRMLFATAVLMVVAVLVGFD----IT 155 Query: 144 GFIGSLLVNSLLVVMLSSFMIYLLSKS---QNPNLPLAISGIVILPMMFLSTVFYPETVF 200 + G L L V S+ M L+ +N A+ +V++P+ F S++F P Sbjct: 156 DWAGLLASVGLSAVFGSALMWVFLTLGVVMKNAQSVQAMGFLVLMPLQFGSSIFAPTDSM 215 Query: 201 ESSKVLSILVSINPMTHASNLVRSFIYGTHLQHSTMVVSLAYLLVLAFIGMLIGLRGFK 259 L NP++ ++ R + G + H + V+LA+ L + I + F+ Sbjct: 216 PG--WLQSFTDYNPLSSLADTARGLMLGGPVAHD-LWVTLAWSAALTAVMAPIAIHKFR 271 >pir||S74047 hypothetical protein c0111 - Sulfolobus solfataricus >gi|1707741|emb|CAA69461.1| (Y08256) orf c01011 [Sulfolobus solfataricus] Length = 192 Score = 72.6 bits (175), Expect = 5e-12 Identities = 52/188 (27%), Positives = 93/188 (48%), Gaps = 7/188 (3%) Query: 70 VLTLVSINQGFRGATTFIQDRFYGGLETLFTLPVPRTVLFMAKILSACIRAII-AMIVLS 128 +L+ + + + + + DR G L+ + T PVPR + + K+LSA IR+++ A IVL Sbjct: 1 MLSFIVLFTSMQSGMSIVWDRRLGVLDRILTTPVPRGNIIIGKVLSAVIRSLVQATIVLV 60 Query: 129 ILTLI-IAKDASITLTGFIGSLLVNSLLVVMLSSFMIYLLSKSQNPNLPLAISGIVILPM 187 + L+ + I F+G L+ LSS + L ++ + +AI ++ LP+ Sbjct: 61 VAVLLGMTFAPEINPLDFLGVYAALFLMSFGLSSLFLMLALRATSWESQMAIMNLLNLPL 120 Query: 188 MFLSTVFYPETVFESSKVLSILVSINPMTHASNLVRSFIYGTHLQHSTMVVSLAYLLVLA 247 +F S FYP V L + INP+T+++ + R + G + + + YL + A Sbjct: 121 LFTSNAFYP--VKSMPYWLKPVAYINPLTYSNGVARGMLLGI---STNLAIDFLYLGLFA 175 Query: 248 FIGMLIGL 255 I IG+ Sbjct: 176 IILSTIGI 183 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.330 0.144 0.401 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 79227167 Number of Sequences: 2977 Number of extensions: 2976386 Number of successful extensions: 15696 Number of sequences better than 1.0e-10: 11 Number of HSP's better than 0.0 without gapping: 1 Number of HSP's successfully gapped in prelim test: 10 Number of HSP's that attempted gapping in prelim test: 15677 Number of HSP's gapped (non-prelim): 11 length of query: 264 length of database: 189,106,746 effective HSP length: 55 effective length of query: 209 effective length of database: 156,189,961 effective search space: 32643701849 effective search space used: 32643701849 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 40 (21.8 bits) S2: 164 (68.3 bits)