BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1722 (PAB1722) DE:SIMILAR TO SEVERAL DNA HELICASES
(872 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||B75073 ATP-dependent RNA helicase homolog PAB1722 - Pyrococ... 1763 0.0
pir||F71092 ATP-dependent RNA helicase homolog PH1003 - Pyrococc... 1449 0.0
pir||E64496 ATP-dependent RNA helicase homolog MJ1574 - Methanoc... 769 0.0
gi|6320497 Ydr291wp [Saccharomyces cerevisiae] >gi|2131417|pir||... 231 3e-59
pir||F69164 ATP-dependent RNA helicase homolog MTH492 - Methanob... 230 4e-59
sp|P50830|YPRA_BACSU HYPOTHETICAL HELICASE IN PONA-COTD INTERGEN... 205 1e-51
dbj|BAB05483.1| (AP001513) ATP-dependent RNA helicase [Bacillus ... 196 9e-49
pir||T38420 probable dna helicases - fission yeast (Schizosaccha... 194 4e-48
pir||B70564 hypothetical protein Rv3649 - Mycobacterium tubercul... 185 2e-45
pir||T36671 probable helicase - Streptomyces coelicolor >gi|4539... 171 3e-41
gb|AAK40384.1| ATP-dependent helicase [Sulfolobus solfataricus] 165 2e-39
pir||H75564 probable ATP-dependent helicase - Deinococcus radiod... 165 2e-39
gb|AAB99596.1| (U67597) M. jannaschii predicted coding region MJ... 158 2e-37
gi|11499982 ATP-dependent RNA helicase, putative [Archaeoglobus ... 155 1e-36
gi|11500031 large helicase-related protein (lhr-2) [Archaeoglobu... 115 2e-24
gi|11498749 large helicase-related protein (lhr-1) [Archaeoglobu... 113 1e-23
gb|AAK40723.1| ATP-dependent helicase [Sulfolobus solfataricus] 112 2e-23
pir||D75091 large helicase-related protein (lhr-2) PAB0744 - Pyr... 112 2e-23
emb|CAC11727.1| (AL445064) hypothetical protein [Thermoplasma ac... 112 2e-23
pir||C71004 probable ATP-dependent helicase - Pyrococcus horikos... 111 3e-23
pir||T35049 probable ATP-dependent helicase - Streptomyces coeli... 111 3e-23
sp|Q57742|HELX_METJA PUTATIVE ATP-DEPENDENT HELICASE MJ0294 >gi|... 111 3e-23
gb|AAK40467.1| ATP-dependent helicase [Sulfolobus solfataricus] 110 6e-23
sp|P95949|HELX_SULSO PUTATIVE ATP-DEPENDENT HELICASE C04010 >gi|... 110 6e-23
pir||B75127 large helicase-related protein (lhr-1) PAB1817 - Pyr... 109 1e-22
pir||G72526 hypothetical protein APE2188 - Aeropyrum pernix (str... 107 7e-22
gb|AAG19610.1| (AE005050) ATP-dependent helicase; HelA [Halobact... 107 7e-22
emb|CAC11967.1| (AL445065) Large helicase related protein [Therm... 106 1e-21
pir||A69140 ATP-dependent helicase - Methanobacterium thermoauto... 101 5e-20
pir||C72521 hypothetical protein APE2144 - Aeropyrum pernix (str... 98 3e-19
gb|AAK41239.1| ATP-dependent helicase [Sulfolobus solfataricus] 98 6e-19
sp|O27830|HELX_METTH PUTATIVE ATP-DEPENDENT HELICASE MTH1802 >gi... 96 2e-18
pir||F83237 probable ATP-dependent DNA helicase PA3272 [imported... 94 8e-18
gi|9755332 C4 zinc finger DNA-binding protein of low sequence sp... 87 6e-16
sp|P51979|HFM1_YEAST HFM1 PROTEIN >gi|780546|gb|AAA93159.1| (U22... 87 1e-15
pir||S61610 HFM1 protein - yeast (Saccharomyces cerevisiae) >gi|... 87 1e-15
emb|CAC11964.1| (AL445065) DNA helicase related protein [Thermop... 80 1e-13
dbj|BAB05326.1| (AP001512) ATP-dependent DNA helicase [Bacillus ... 78 5e-13
gi|7305019 eukaryotic translation initiation factor 4A2 [Mus mus... 77 7e-13
prf||1413329A gene vasa [Drosophila melanogaster] 76 2e-12
emb|CAB90153.1| (AL355013) putative atp-dependent RNA helicase [... 76 2e-12
gi|11500032 SKI2-family helicase [Archaeoglobus fulgidus] 75 3e-12
pir||S01676 ATP-dependent RNA helicase homolog - fruit fly (Dros... 75 4e-12
gi|10957431 RNA helicase, putative [Deinococcus radiodurans] >gi... 75 4e-12
pir||T50496 hypothetical protein T22D6.50 - Arabidopsis thaliana... 75 4e-12
gb|AAG22819.1|AF302423_1 (AF302423) RNA helicase II/Gu [Xenopus ... 75 4e-12
pir||C69187 conserved hypothetical protein MTH656 - Methanobacte... 75 5e-12
sp|Q09811|HUS2_SCHPO ATP-DEPENDENT DNA HELICASE HUS2 >gi|2130397... 74 6e-12
pir||H64474 hypothetical protein MJ1401 - Methanococcus jannasch... 74 6e-12
pir||G71051 probable ATP-dependent helicase LHR - Pyrococcus hor... 74 6e-12
gi|11435040 similar to eukaryotic translation initiation factor ... 73 1e-11
emb|CAA40268.1| (X56953) protein synthesis initiation factor 4A ... 73 1e-11
emb|CAA73168.1| (Y12591) translation initiation factor eIF4A II ... 73 1e-11
pir||A31922 ATP-dependent RNA helicase homolog - fruit fly (Dros... 73 1e-11
gb|AAF44917.1|AE003406_122 (AE003416) symbol=vas; synonym=BG:DS0... 73 1e-11
emb|CAA26842.1| (X03039) put. eIF-4A (aa 1-390) [Mus musculus] >... 72 2e-11
emb|CAA26843.1| (X03039) put. altern. eIF-4A (aa 1-370) [Mus mus... 72 2e-11
pir||S00986 translation initiation factor eIF-4A I - mouse 72 2e-11
gi|4503529 eukaryotic translation initiation factor 4A, isoform ... 72 2e-11
sp|P29562|IF41_RABIT EUKARYOTIC INITIATION FACTOR 4A-I (EIF-4A-I... 72 2e-11
pir||S13269 translation initiation factor eIF-4A.I - rabbit (fra... 72 2e-11
pir||JS0039 translation initiation factor eIF-4A - mouse >gi|556... 72 3e-11
gi|4503531 eukaryotic translation initiation factor 4A, isoform ... 72 3e-11
dbj|BAB02697.1| (AB018114) helicase-like protein [Arabidopsis th... 72 3e-11
gb|AAK42080.1| ATP-dependent RNA helicase [Sulfolobus solfataricus] 71 4e-11
emb|CAA73167.1| (Y12590) translation initiation factor eIF4A I [... 71 4e-11
gb|AAK42222.1| ATP-dependent RNA helicase [Sulfolobus solfataricus] 71 5e-11
sp|P27639|IF4A_CAEEL EUKARYOTIC INITIATION FACTOR 4A (EIF-4A) (E... 71 7e-11
gb|AAD34681.1|AC006341_9 (AC006341) Similar to gb|L13612 DEAD-bo... 71 7e-11
pir||T38238 hypothetical protein SPAC23A1.19c - fission yeast (... 70 9e-11
gb|AAG22818.1|AF302422_1 (AF302422) RNA helicase II/Gu [Xenopus ... 70 9e-11
>pir||B75073 ATP-dependent RNA helicase homolog PAB1722 - Pyrococcus abyssi
(strain Orsay) >gi|5458399|emb|CAB49887.1| (AJ248286)
SIMILAR TO SEVERAL DNA HELICASES [Pyrococcus abyssi]
Length = 872
Score = 1763 bits (4516), Expect = 0.0
Identities = 872/872 (100%), Positives = 872/872 (100%)
Query: 1 MIDVFKGLESEIVNLHEIPPRKGSYGSFKFRHEEVNKLVEELGFKLYSHQVEALKLLYSG 60
MIDVFKGLESEIVNLHEIPPRKGSYGSFKFRHEEVNKLVEELGFKLYSHQVEALKLLYSG
Sbjct: 1 MIDVFKGLESEIVNLHEIPPRKGSYGSFKFRHEEVNKLVEELGFKLYSHQVEALKLLYSG 60
Query: 61 KNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFLLIYPTRALINNQLEKFERENEIFSKI 120
KNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFLLIYPTRALINNQLEKFERENEIFSKI
Sbjct: 61 KNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFLLIYPTRALINNQLEKFERENEIFSKI 120
Query: 121 TGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDYKWLFKNLKLLVV 180
TGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDYKWLFKNLKLLVV
Sbjct: 121 TGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDYKWLFKNLKLLVV 180
Query: 181 DELHIYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKDFAEKFFGFEFEEVT 240
DELHIYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKDFAEKFFGFEFEEVT
Sbjct: 181 DELHIYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKDFAEKFFGFEFEEVT 240
Query: 241 EAGNPSPKRYIIMFEPTRFSGEQLIRQIVERLVENDVKTLVFFDSRKGTERIMRMFLGSK 300
EAGNPSPKRYIIMFEPTRFSGEQLIRQIVERLVENDVKTLVFFDSRKGTERIMRMFLGSK
Sbjct: 241 EAGNPSPKRYIIMFEPTRFSGEQLIRQIVERLVENDVKTLVFFDSRKGTERIMRMFLGSK 300
Query: 301 VFNLITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGL 360
VFNLITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGL
Sbjct: 301 VFNLITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGL 360
Query: 361 FSLIQRFGRAGRDPNRVAINGIVLRRNGLDYYYKEHFEELVEGIEKGLVEGIPVNLDNER 420
FSLIQRFGRAGRDPNRVAINGIVLRRNGLDYYYKEHFEELVEGIEKGLVEGIPVNLDNER
Sbjct: 361 FSLIQRFGRAGRDPNRVAINGIVLRRNGLDYYYKEHFEELVEGIEKGLVEGIPVNLDNER 420
Query: 421 IAKKHLHYLLSELGVVDVNEIPEHWRIALRPLKEEGIVEEYLNPLTNKVEIRIKKPAIYS 480
IAKKHLHYLLSELGVVDVNEIPEHWRIALRPLKEEGIVEEYLNPLTNKVEIRIKKPAIYS
Sbjct: 421 IAKKHLHYLLSELGVVDVNEIPEHWRIALRPLKEEGIVEEYLNPLTNKVEIRIKKPAIYS 480
Query: 481 SIRSTSDESFFLVKDEGWIRSSLVRKSGGELLRFVNYLKARGFIIEEVDEVEFYRSLLPG 540
SIRSTSDESFFLVKDEGWIRSSLVRKSGGELLRFVNYLKARGFIIEEVDEVEFYRSLLPG
Sbjct: 481 SIRSTSDESFFLVKDEGWIRSSLVRKSGGELLRFVNYLKARGFIIEEVDEVEFYRSLLPG 540
Query: 541 MVYPSRGRLFMVIDKINVDKFHFVFAQEIPMNEDVETNVHKSENVEVLKVQDEKSFGPIK 600
MVYPSRGRLFMVIDKINVDKFHFVFAQEIPMNEDVETNVHKSENVEVLKVQDEKSFGPIK
Sbjct: 541 MVYPSRGRLFMVIDKINVDKFHFVFAQEIPMNEDVETNVHKSENVEVLKVQDEKSFGPIK 600
Query: 601 VYFGRLKVTHEYLGYAVKGKDVERHVERLERLRDAGILRGEIEFNVTMFEEWWKFARVSF 660
VYFGRLKVTHEYLGYAVKGKDVERHVERLERLRDAGILRGEIEFNVTMFEEWWKFARVSF
Sbjct: 601 VYFGRLKVTHEYLGYAVKGKDVERHVERLERLRDAGILRGEIEFNVTMFEEWWKFARVSF 660
Query: 661 YSPYKREFETEGVWLVFPRSIDEVPAEEFRHFFSIASEYNYELAMFLFNKLSRGVLFPSL 720
YSPYKREFETEGVWLVFPRSIDEVPAEEFRHFFSIASEYNYELAMFLFNKLSRGVLFPSL
Sbjct: 661 YSPYKREFETEGVWLVFPRSIDEVPAEEFRHFFSIASEYNYELAMFLFNKLSRGVLFPSL 720
Query: 721 LGATTHYIRAVIRKVAKEEGLDENFVFAVKKMVDSKDGVKSGLHAIEHNLIKIAPVVTHV 780
LGATTHYIRAVIRKVAKEEGLDENFVFAVKKMVDSKDGVKSGLHAIEHNLIKIAPVVTHV
Sbjct: 721 LGATTHYIRAVIRKVAKEEGLDENFVFAVKKMVDSKDGVKSGLHAIEHNLIKIAPVVTHV 780
Query: 781 DSRELGGYSYDDFNGLPTIFIYDGNEGGSGIARLIYENIEKLIVRSREHIAKCPCKDGCP 840
DSRELGGYSYDDFNGLPTIFIYDGNEGGSGIARLIYENIEKLIVRSREHIAKCPCKDGCP
Sbjct: 781 DSRELGGYSYDDFNGLPTIFIYDGNEGGSGIARLIYENIEKLIVRSREHIAKCPCKDGCP 840
Query: 841 ACVYSPKCGTFNEFLDKWMAIKIWDKVLNQKV 872
ACVYSPKCGTFNEFLDKWMAIKIWDKVLNQKV
Sbjct: 841 ACVYSPKCGTFNEFLDKWMAIKIWDKVLNQKV 872
>pir||F71092 ATP-dependent RNA helicase homolog PH1003 - Pyrococcus horikoshii
>gi|3257417|dbj|BAA30100.1| (AP000004) 873aa long
hypothetical helicase [Pyrococcus horikoshii]
Length = 873
Score = 1449 bits (3709), Expect = 0.0
Identities = 687/869 (79%), Positives = 786/869 (90%)
Query: 3 DVFKGLESEIVNLHEIPPRKGSYGSFKFRHEEVNKLVEELGFKLYSHQVEALKLLYSGKN 62
++FKGLE+EIVN EIPPR G YG FKF++ EVN+LV+ LGF+LYSHQV+AL LLYSGKN
Sbjct: 4 ELFKGLETEIVNADEIPPRSGKYGDFKFKNREVNELVKRLGFRLYSHQVKALNLLYSGKN 63
Query: 63 VVVSTPTASGKSEIFRLFIFDEFLEDSSSTFLLIYPTRALINNQLEKFERENEIFSKITG 122
VVVSTPTASGKSEIFRLFIFD FLE+ SSTFLL+YPTRALINNQ+EKF+ EN++F++ITG
Sbjct: 64 VVVSTPTASGKSEIFRLFIFDSFLENPSSTFLLVYPTRALINNQMEKFDNENKVFAEITG 123
Query: 123 RKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDYKWLFKNLKLLVVDE 182
KV SILTGDV+ SER++I R KPNVIFTTPDMLH+ +LPRWL+YKWL KNLKLLVVDE
Sbjct: 124 MKVKASILTGDVDWSERKKIVRNKPNVIFTTPDMLHHTILPRWLEYKWLLKNLKLLVVDE 183
Query: 183 LHIYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKDFAEKFFGFEFEEVTEA 242
LH YRGVFGSNVAYVFRR+F RLRRL +P ILALSATL+NPK+FAE FFGFEFEEVTEA
Sbjct: 184 LHTYRGVFGSNVAYVFRRVFFRLRRLNSSPLILALSATLRNPKEFAESFFGFEFEEVTEA 243
Query: 243 GNPSPKRYIIMFEPTRFSGEQLIRQIVERLVENDVKTLVFFDSRKGTERIMRMFLGSKVF 302
GNPSP+RYIIMFEP RFSGEQLI+Q++++L+ N+VKTLVFFDSRKGTERIMRMFL S+ F
Sbjct: 244 GNPSPRRYIIMFEPKRFSGEQLIKQVIDKLIRNNVKTLVFFDSRKGTERIMRMFLFSEFF 303
Query: 303 NLITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFS 362
+ ITTYKGTLTKLERW+IE DFREG LK LL TNALELGIDVGDLDAVINYGIPSDGLFS
Sbjct: 304 DKITTYKGTLTKLERWKIERDFREGNLKVLLATNALELGIDVGDLDAVINYGIPSDGLFS 363
Query: 363 LIQRFGRAGRDPNRVAINGIVLRRNGLDYYYKEHFEELVEGIEKGLVEGIPVNLDNERIA 422
LIQRFGRAGRDPNRVAINGI+LR+NGLDYYYKEHF+ELVEGIEKGLV+ IPVNL NE+IA
Sbjct: 364 LIQRFGRAGRDPNRVAINGIILRKNGLDYYYKEHFDELVEGIEKGLVDKIPVNLGNEKIA 423
Query: 423 KKHLHYLLSELGVVDVNEIPEHWRIALRPLKEEGIVEEYLNPLTNKVEIRIKKPAIYSSI 482
KKHLHYLLSELGVV +EIPE+W L LK EGIV+EY NP+T K E+R++KPA+YSSI
Sbjct: 424 KKHLHYLLSELGVVGKDEIPEYWVKVLEDLKHEGIVDEYKNPITGKFEVRVRKPAVYSSI 483
Query: 483 RSTSDESFFLVKDEGWIRSSLVRKSGGELLRFVNYLKARGFIIEEVDEVEFYRSLLPGMV 542
R+ SDESFFLV DEGWIR +L RK G ELLRF+NYLKARG IIEEVDEVEF+RSLLPGMV
Sbjct: 484 RTASDESFFLVIDEGWIRRTLRRKRGIELLRFINYLKARGLIIEEVDEVEFHRSLLPGMV 543
Query: 543 YPSRGRLFMVIDKINVDKFHFVFAQEIPMNEDVETNVHKSENVEVLKVQDEKSFGPIKVY 602
YPSRGRL+M +D++ V+KF+FVFA+EIPMNED+ETNV K E+VE+L + K+ GP+KVY
Sbjct: 544 YPSRGRLYMAVDRLKVEKFNFVFAREIPMNEDLETNVSKVESVEILNTYEGKNIGPVKVY 603
Query: 603 FGRLKVTHEYLGYAVKGKDVERHVERLERLRDAGILRGEIEFNVTMFEEWWKFARVSFYS 662
FGR++V EY GYAVKGKDVE+HV+RLE+L+D GILRGE+E VTMFE+WWKFARVSFY
Sbjct: 604 FGRIRVKQEYNGYAVKGKDVEKHVDRLEKLKDEGILRGEVEVAVTMFEDWWKFARVSFYD 663
Query: 663 PYKREFETEGVWLVFPRSIDEVPAEEFRHFFSIASEYNYELAMFLFNKLSRGVLFPSLLG 722
PY REFETEG+WL+FP+ I++VPAEEFR+FFSIAS+YNY+LAMFLFNKLSR +LFPSLLG
Sbjct: 664 PYVREFETEGIWLIFPKEIEDVPAEEFRYFFSIASDYNYDLAMFLFNKLSRKMLFPSLLG 723
Query: 723 ATTHYIRAVIRKVAKEEGLDENFVFAVKKMVDSKDGVKSGLHAIEHNLIKIAPVVTHVDS 782
AT+HYIR +I K AK+EGL E+F+FAVKKM+DSKDG+ SGLHAIEHNLIKIAPVVT+VDS
Sbjct: 724 ATSHYIRRIIEKYAKDEGLGEDFIFAVKKMIDSKDGIGSGLHAIEHNLIKIAPVVTYVDS 783
Query: 783 RELGGYSYDDFNGLPTIFIYDGNEGGSGIARLIYENIEKLIVRSREHIAKCPCKDGCPAC 842
RELGGYSYD+FNG P IFIYDGNEGGSGI + IYENIEKL+VRSREHIAKCPCKDGCPAC
Sbjct: 784 RELGGYSYDNFNGFPVIFIYDGNEGGSGIVKSIYENIEKLMVRSREHIAKCPCKDGCPAC 843
Query: 843 VYSPKCGTFNEFLDKWMAIKIWDKVLNQK 871
+YSPKCGTFNEFLDKWMAIKIW+KVL+ K
Sbjct: 844 IYSPKCGTFNEFLDKWMAIKIWEKVLDHK 872
>pir||E64496 ATP-dependent RNA helicase homolog MJ1574 - Methanococcus
jannaschii >gi|1592195|gb|AAB99590.1| (U67597)
ATP-dependent RNA helicase, eIF-4A family, putative
[Methanococcus jannaschii]
Length = 684
Score = 769 bits (1964), Expect = 0.0
Identities = 377/679 (55%), Positives = 509/679 (74%), Gaps = 7/679 (1%)
Query: 1 MIDVFKGLESEIVNLHEIPPRKGSYGSFKFRHEEVNKLVEELGFKLYSHQVEALKLLYSG 60
M DVFKG+E EI+ +++IP RKG + +FKF+++E+N+L++ LGFKLY HQV+ALK LY+
Sbjct: 1 MEDVFKGIEKEIIKIYKIPERKGRFSNFKFKNKEINELIDALGFKLYLHQVKALKYLYNK 60
Query: 61 KNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFLLIYPTRALINNQLEKFERENEIFSKI 120
K+VVV+T TASGKSEIFRL IFD FL + +LLIYPTRALINNQ EKF ENE+F KI
Sbjct: 61 KDVVVTTSTASGKSEIFRLAIFDNFLSNPDDRYLLIYPTRALINNQYEKFSMENELFYKI 120
Query: 121 TGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDYKWLFKNLKLLVV 180
T ++V ILTGDV L +RR I ++KPNV+FTTPDMLHY +L +Y WL KNLKLLVV
Sbjct: 121 TNKRVKAEILTGDVGLEKRREILKDKPNVLFTTPDMLHYQILKNHNNYLWLLKNLKLLVV 180
Query: 181 DELHIYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKDFAEKFFGFEFEEVT 240
DELH+YRGVFG+N+ YVF+RL L+RL N +IL LSATLKNPK+F + F +FE V
Sbjct: 181 DELHVYRGVFGTNMVYVFKRLLKLLKRLNNNLQILCLSATLKNPKEFVKLLFNRDFEVVD 240
Query: 241 EAGNPSPKRYIIMFEPTRFSGEQLIRQIVERLVENDVKTLVFFDSRKGTERIMRMFLGSK 300
++ NPS ++Y+ + EP +QL+R+++E LV+N++KTLVFFD+RK TE++MR L SK
Sbjct: 241 KSYNPSSRKYLAILEPKNLDNKQLLRRLIENLVDNNIKTLVFFDTRKETEKLMRFLLNSK 300
Query: 301 VFNLITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGL 360
VF ++TYKGTL K R IE F+ G++ ALLTTNALELGID+GDLDAVINYGIP DG+
Sbjct: 301 VFYKLSTYKGTLPKYVREEIEEKFKNGEILALLTTNALELGIDIGDLDAVINYGIPPDGI 360
Query: 361 FSLIQRFGRAGRDPNRVAINGIVLRRNGLDYYYKEHFEELVEGIEKGLVEGIPVNLDNER 420
FSLIQRFGRAGR ++ A+N IVLR++GLDYYYKEH EL E I KG++E +PVN+ N
Sbjct: 361 FSLIQRFGRAGR-RDKEALNIIVLRKDGLDYYYKEHLNELYERIRKGIIEYMPVNIKNRF 419
Query: 421 IAKKHLHYLLSELGVVDVNEIPEHWRIALRPLKEEGIVEEYLNPLTNKVEIRIKKPAIYS 480
+ KKHLHYL+SEL +VD +E+ + + ++ L+ EG ++ Y NP+TNK EIR K IYS
Sbjct: 420 VTKKHLHYLISELKIVDFDELNDFEKEIVKELEREGKIKIYKNPITNKTEIRNVKQPIYS 479
Query: 481 SIRSTSDESFFLVKDEGWIRSSLVRKSGGELLRFVNYLKARGFIIEEVDEVEFYRSLLPG 540
SIR+ SDES++L+ D+ WI+S L+ K+ E+L F+N+LK +G++IEEVD+ E+YRSL+ G
Sbjct: 480 SIRTASDESYYLILDKPWIKSKLLNKTQSEILSFINWLKIKGYVIEEVDKDEYYRSLITG 539
Query: 541 MVYPSRGRLFMVIDKINVDKFHFVFAQEIPMNEDVETNVHKSENVEVLKVQDEKSFGPIK 600
M Y SRG+LF+ DKI + KFHF+FA E+ M DVE K E +++L + D+KS+ I
Sbjct: 540 MPYFSRGKLFIAKDKIGIRKFHFIFADELDMFWDVEALQKKEEEIDILDIYDKKSYKDID 599
Query: 601 VYFGRLKVTHEYLGYAVKGKDVERHVERLERLRDAGILRGEIEFNVTMFEEWW--KFARV 658
+Y+GRL+V Y G+ V+G DV+++ + L L+D GIL EI+ +F++++ F V
Sbjct: 600 IYYGRLRVRKIYEGFIVRGVDVDKYYQELLALKDNGILDAEID----LFKDFFGLNFISV 655
Query: 659 SFYSPYKREFETEGVWLVF 677
F R+FET+G+WL +
Sbjct: 656 KFNKKIIRDFETDGIWLCY 674
>gi|6320497 Ydr291wp [Saccharomyces cerevisiae] >gi|2131417|pir||S70120
ATP-dependent RNA helicase homolog YDR291w - yeast
(Saccharomyces cerevisiae) >gi|1230655|gb|AAB64466.1|
(U51031) Ydr291wp [Saccharomyces cerevisiae]
Length = 1077
Score = 231 bits (583), Expect = 3e-59
Identities = 200/644 (31%), Positives = 330/644 (51%), Gaps = 69/644 (10%)
Query: 1 MIDVFKGLE---SEIVNLHEIPPRKGSYGSFKFR-HEEVNKLVEELGFKLYSHQVEALKL 56
MI+ K E S+I + IP R Y F EV + +E F YSHQ +A+
Sbjct: 244 MIEKLKSTEFYASQIKHCFTIPSRTAKYKGLCFELAPEVYQGMEHENF--YSHQADAINS 301
Query: 57 LYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFLLIYPTRALINNQLEKFERENEI 116
L+ G+NV+++T T+SGKS I++L D L+D STF+ I+PT+AL +Q F+ I
Sbjct: 302 LHQGENVIITTSTSSGKSLIYQLAAIDLLLKDPESTFMYIFPTKALAQDQKRAFK---VI 358
Query: 117 FSKITGRKVGNSILT---GDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDYKWLFK 173
SKI K N+++ GD E ER IR+ VIFT PDM+H ++LP +++
Sbjct: 359 LSKIPELK--NAVVDTYDGDTEPEERAYIRKNA-RVIFTNPDMIHTSILPNHANWRHFLY 415
Query: 174 NLKLLVVDELHIYRGVFGSNVAYVFRRLFLRLRRLKVNP--RILALSATLKNPKDFAEKF 231
+LKL+VVDELHIY+G+FGS+VA V RRL N + ++ SATLK+P +
Sbjct: 416 HLKLVVVDELHIYKGLFGSHVALVMRRLLRLCHCFYENSGLQFISCSATLKSPVQHMKDM 475
Query: 232 FGF-EFEEVTEAGNPSPKRYIIMFEPT-----RFSGEQLIRQ---IVERLVENDVKTLVF 282
FG E + E G+P+ ++++++ P E IR+ I+ +L+ N+V+T+ F
Sbjct: 476 FGINEVTLIHEDGSPTGAKHLVVWNPPILPQHERKRENFIRESAKILVQLILNNVRTIAF 535
Query: 283 FDSRKGTERIMR----MFLGSKVFNLIT---TYKGTLTKLERWRIESDFREGKLKALLTT 335
R+ E +M+ +F+ + +L+T +Y+G + +R +IE + G LKA+++T
Sbjct: 536 CYVRRVCELLMKEVRNIFIETGREDLVTEVMSYRGGYSASDRRKIEREMFHGNLKAVIST 595
Query: 336 NALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNRVAINGIVLRRNGLDYYYKE 395
NALELGID+G LDAV+ G P + + Q+ GRAGR N ++ +V + +D +Y
Sbjct: 596 NALELGIDIGGLDAVLMCGFPL-SMANFHQQSGRAGR-RNNDSLTLVVASDSPVDQHYVA 653
Query: 396 HFEELVEGIEKGLVEGIPVNLDNERIAKKHLHYLLSELGVVDVNEIPEHWRIALRPLKEE 455
H E L+E + + ++ +N I + H+ EL + + ++
Sbjct: 654 HPESLLEVNNFESYQDLVLDFNNILILEGHIQCAAFELPINFERD-------------KQ 700
Query: 456 GIVEEYLNPLTNKVEIRIKKPAIYSSIRSTSDESFFLVKDEGWIRSSLVRKSGGELLRF- 514
E +L + + + + ++S R FL W S V GGE +F
Sbjct: 701 YFTESHLRKICVE-RLHHNQDGYHASNR-------FL----PW-PSKCVSLRGGEEDQFA 747
Query: 515 -VNYLKARGFIIEEVDEVEFYRSLLPGMVYPSRGRLFMVIDKINVDKFHFVFAQEIPMNE 573
V+ R IIEE++ +L G ++ +G ++V + N D+ +A+ ++
Sbjct: 748 VVDITNGRNIIIEEIEASRTSFTLYDGGIFIHQGYPYLV-KEFNPDE---RYAKVQRVDV 803
Query: 574 DVETNVHKSENVEVLKVQDEKSF--GPIKVYFGRLKVTHEYLGY 615
D TN +V+ +++ +S + VYFG++K T G+
Sbjct: 804 DWVTNQRDFTDVDPQEIELIRSLRNSDVPVYFGKIKTTIIVFGF 847
>pir||F69164 ATP-dependent RNA helicase homolog MTH492 - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621563|gb|AAB84998.1| (AE000833) ATP-dependent RNA
helicase, eIF-4A family [Methanobacterium
thermoautotrophicum]
Length = 822
Score = 230 bits (581), Expect = 4e-59
Identities = 184/620 (29%), Positives = 291/620 (46%), Gaps = 64/620 (10%)
Query: 12 IVNLHEIPPRKGSYGSFKFRHEEVNKLVEELGFKLYSHQVEALKLLYSGKNVVVSTPTAS 71
I ++ IP R+ Y + + ++ G +LY HQ EAL + G N++++TPTAS
Sbjct: 19 IEHVETIPGREARYSDSTDIPDNIRDYLDAGGIRLYRHQREALDAIREGMNILITTPTAS 78
Query: 72 GKSEIFRLFIFDEFLEDSSSTFLLIYPTRALINNQLEKFER-ENEIFSKITGRKVGNSIL 130
GK+ F L I + + +T L IYP +AL +QL E E+E+ G K+ S
Sbjct: 79 GKTLAFNLPIMETLTLNPDATALYIYPVKALSRDQLGVLEELESEL-----GLKLNPSTY 133
Query: 131 TGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDYKWLFKNLKLLVVDELHIYRGVF 190
GD ERR RE VI T P LH +LP ++ + NL+ +V+DE H YRGVF
Sbjct: 134 DGDTP-RERRPWIRENSRVILTNPHQLH-RILPWHHQWRRFYSNLRYVVIDEAHQYRGVF 191
Query: 191 GSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKDFAEKFFGFEFEEVTEAGNPSPKRY 250
GSNVA + RRL R P+ + SATL NP +F+ K G +F +++ +PS ++
Sbjct: 192 GSNVALLLRRLRRICRYYGSEPQFVLASATLANPAEFSRKLTGLDFRVISDDTSPSGPKH 251
Query: 251 IIMFEPTRFSGEQLIR----QIVERLVENDVKTLVFFDSRKGTERIMRMFL------GSK 300
I++ P R G+ I+ LV V+TL F SRK E + R K
Sbjct: 252 FILYNPYRKRGDPSAHLETSAILSYLVLRGVQTLCFTISRKMAELVTRWTREQLDRENRK 311
Query: 301 VFNLITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGL 360
+ + +T+Y+ +R RIE+D +EG+L + TNALELGID+G LDAVI G P +
Sbjct: 312 LVDRVTSYRAGYLAEQRRRIEADLKEGRLLGVTATNALELGIDIGSLDAVIISGYPGT-M 370
Query: 361 FSLIQRFGRAGRDPNRVAINGIVLRRNGLDYYYKEHFEELVEGIEKGLVEGIPVNLDNER 420
S Q+ GRAGR+ + +V N LD Y ++ + E + + ++L N
Sbjct: 371 ISTWQQAGRAGRNLKDSMVI-LVAFENPLDQYIMKNPSFIFERPHENAI----IDLQNRL 425
Query: 421 IAKKHLHYLLSELGVVDVNEIPEHWRIALR-PLKEEGIVEEYLNPLTNKVEIRIKKPAIY 479
I + SEL ++ + + + + + + +G +E + LT + P
Sbjct: 426 ILRNQTACAASELPLILDDFLEYDFSVGVAGEMLADGELELAPDGLTCSGD-----PQFR 480
Query: 480 SSIRSTSDESFFLVKDEGWIRSSLVRKSGGELLRFVNYLKARGFIIEEVDEVEFYRSLLP 539
+ S ++F ++ G ++E + + YR
Sbjct: 481 YGLDDVSQDTFTVI--------------------------CEGRVLETMSRSQAYREAHE 514
Query: 540 GMVYPSRGRLFMVIDKINVDKFHFVFAQEIPMNEDVE--TNVHKSENVEVLKVQDEKSFG 597
G V + G + V D F + I DVE T+V + + +++ ++ G
Sbjct: 515 GAVLMNHGNTYTVRD------FDLEGRRIIVDRRDVEYHTSVLRDTELRIIRKLRQRRLG 568
Query: 598 PIKVYFGRLKVTHEYLGYAV 617
++V FG ++VT Y GY V
Sbjct: 569 DLEVNFGEVEVTEHYTGYRV 588
Score = 82.7 bits (201), Expect = 2e-14
Identities = 44/117 (37%), Positives = 63/117 (53%), Gaps = 4/117 (3%)
Query: 757 DGVKSGLHAIEHNLIKIAPVVTHVDSRELGGYS---YDDFNGLPTIFIYDGNEGGSGIAR 813
D G+H E LI + P+ D ++GG S + D TIFIYDG EGG G+A
Sbjct: 631 DAFHGGIHGAEDALISLFPLHVLCDRSDIGGISTPMHPDTQEA-TIFIYDGFEGGIGLAE 689
Query: 814 LIYENIEKLIVRSREHIAKCPCKDGCPACVYSPKCGTFNEFLDKWMAIKIWDKVLNQ 870
E L+ + E ++ C C +GCP+C+YSPKCG N L + +KI + ++ Q
Sbjct: 690 KGVEVFGDLLASTLELVSSCSCTEGCPSCIYSPKCGNENSPLHRDATVKILEYLMEQ 746
>sp|P50830|YPRA_BACSU HYPOTHETICAL HELICASE IN PONA-COTD INTERGENIC REGION
>gi|7446091|pir||B69941 ATP-dependent RNA helicase
homolog yprA - Bacillus subtilis
>gi|1146178|gb|AAB38468.1| (L47838) helicase [Bacillus
subtilis] >gi|2634641|emb|CAB14139.1| (Z99115) similar
to ATP-dependent helicase [Bacillus subtilis]
Length = 749
Score = 205 bits (517), Expect = 1e-51
Identities = 161/535 (30%), Positives = 262/535 (48%), Gaps = 46/535 (8%)
Query: 1 MIDVFKGLESEIVNLHEIPPRKGSYGSF-KFRHEEVNKLVEELGF-KLYSHQVEALKLLY 58
+I KG E+ +VN HEI PR+ + E + + + G +LY+HQ A + +
Sbjct: 9 LISDLKGNEN-VVNWHEIEPREAKTRPMPESIDERIKAALSKRGIDELYTHQYSAFQYVQ 67
Query: 59 SGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFLLIYPTRALINNQLEKFERENEIFS 118
G+++V TPTASGK+ + L + +D ++ L ++PT+AL +Q + NEI
Sbjct: 68 KGESIVTVTPTASGKTLCYNLPVLQSIAQDETNRALYLFPTKALAQDQKSEL---NEIID 124
Query: 119 KITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDYKWLFKNLKLL 178
++ G + + GD + R+++R+ +++ T PDMLH +LP + LF+NLK +
Sbjct: 125 EM-GIDIKSFTYDGDTSPAIRQKVRKAG-HIVITNPDMLHSAILPHHTKWVSLFENLKYI 182
Query: 179 VVDELHIYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKDFAEKFFGFEFEE 238
V+DELH YRGVFGS+VA V RRL R +P + SAT+ NPK+ E+ G
Sbjct: 183 VIDELHTYRGVFGSHVANVIRRLKRICRFYGSDPVFICTSATIANPKELGEQLTGKPMRL 242
Query: 239 VTEAGNPSPKRYIIMFEP--------TRFSGEQLIRQIVERLVENDVKTLVFFDSRKGTE 290
V + G PS +++ + + P R S + ++ + ++N V+T+VF SR E
Sbjct: 243 VDDNGAPSGRKHFVFYNPPIVNKPLNIRRSATAEVNELAKEFLKNKVQTIVFARSRVRVE 302
Query: 291 -------RIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGID 343
+++ +G+K I Y+G ER IE REG + +++TNALELG+D
Sbjct: 303 IILSHIQELVKKEIGTK---SIRGYRGGYLPKERREIERGLREGDILGVVSTNALELGVD 359
Query: 344 VGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNRVAINGIVLRRNGLDYYYKEHFEELVEG 403
+G L + G P + S Q+ GRAGR I +V +D Y H E
Sbjct: 360 IGQLQVCVMTGYPG-SVASAWQQAGRAGRRHGESLII-MVANSTPIDQYIVRHPEYFFNR 417
Query: 404 IEKGL---VEGIPVNLDNERIAKKHLHYLL-SELGVVDVNEIPEHWRIALRPLKEEGIVE 459
+ E + + +D+ + A L + E G ++V++I E+ L+EE ++
Sbjct: 418 SPESARINPENLIILVDHLKCAAYELPFRADEEFGAMEVSDILEY-------LQEEAVLH 470
Query: 460 EYLNPLTNKVEIRIKKPAIYSSIRSTSDESFFLVKDEGWIRSSLVRKSGGELLRF 514
E PA S+RS S E+ +V ++ GE+ RF
Sbjct: 471 RNGERYHWASE---SFPASNISLRSASQENVVIVDQSDIANVRII----GEMDRF 518
>dbj|BAB05483.1| (AP001513) ATP-dependent RNA helicase [Bacillus halodurans]
Length = 764
Score = 196 bits (493), Expect = 9e-49
Identities = 161/536 (30%), Positives = 254/536 (47%), Gaps = 61/536 (11%)
Query: 8 LESEIVNLHEIPPRKGSYGSFKFRHE-EVNKLVEELGF-KLYSHQVEALKLLYSGKNVVV 65
++ IV+ HEI + F + + + +E+ G +LY+HQ A + G++VV
Sbjct: 19 IKKNIVHWHEIEAKPAQTMPFPTTLDIRIREALEKRGIGQLYTHQNTAYECSEKGEHVVA 78
Query: 66 STPTASGKSEIFRLFIFDEFLEDSSSTFLLIYPTRALINNQLEKFERENEIFSKITGRKV 125
TPTASGK+ + L + + D SS L ++PT+AL +Q + NEI ++ G V
Sbjct: 79 VTPTASGKTLCYNLPVLQQIRRDESSRALYLFPTKALAQDQKSEL---NEIIEEM-GISV 134
Query: 126 GNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDYKWLFKNLKLLVVDELHI 185
GD + R+ +R+ +V+ T PDMLH +LP + F+NLK +V+DELH
Sbjct: 135 KCFTYDGDTAPNIRQAVRKAG-HVVITNPDMLHSAILPHHTKWVAFFENLKYVVIDELHT 193
Query: 186 YRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKDFAEKFFGFEFEEVTEAGNP 245
YRGVFGS+VA V RRL R P + SAT+ NP++ A + G + G P
Sbjct: 194 YRGVFGSHVANVIRRLKRIARYYGSEPTFICTSATIANPQELASQLTGHNVRLIDNNGAP 253
Query: 246 SPKRYIIMFEP--------TRFSGEQLIRQIVERLVENDVKTLVFFDSRKGTERIMRMF- 296
S K++ + + P R S + ++ ++ +EN+++T+VF SR E I+
Sbjct: 254 SGKKHFVFYNPPVVNEPLNIRKSATVEVNRLAKKFLENNIQTIVFARSRVRVEVILSHLQ 313
Query: 297 -LGSKVF--NLITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINY 353
L K + Y+G +R IE R G + +++TNALELG+D+G L I
Sbjct: 314 ELTKKKIGQQAVRGYRGGYLPKQRREIERGLRNGDIIGVVSTNALELGVDIGQLQVCIMT 373
Query: 354 GIPSDGLFSLIQRFGRAGRDPNRVAINGIVLRRNGLDYYYKEHFEELVEGIEKGLVEGIP 413
G P + S Q+ GRAGR + ++ +V + +D Y +H + +E E +
Sbjct: 374 GYPG-SIASAWQQSGRAGRRQHE-SLTLLVAGSSPIDQYMIQHPDYFLEKSP----ESVR 427
Query: 414 VNLDNERIAKKHLHYLLSELGVVDVNEIPEHWRIALRPLKE----EGI-VEEYLNPLTNK 468
+N DN I HL EL P KE +G+ +EE L LT +
Sbjct: 428 INRDNLIILVDHLKCAAYEL-----------------PFKEGETLDGVEIEEILEFLTEE 470
Query: 469 VEIRIKK----------PAIYSSIRSTSDESFFLVKDEGWIRSSLVRKSGGELLRF 514
+ + PA S+RS S E+ ++ ++ GE+ RF
Sbjct: 471 HVLHHRGSKWYWMNDGFPAHGISLRSASQENVVIIDQSDIANPQVI----GEMDRF 522
>pir||T38420 probable dna helicases - fission yeast (Schizosaccharomyces pombe)
(fragment) >gi|2656007|emb|CAB16187.1| (Z99126)
DEAD/DEAH box helicase [Schizosaccharomyces pombe]
Length = 643
Score = 194 bits (488), Expect = 4e-48
Identities = 132/374 (35%), Positives = 200/374 (53%), Gaps = 31/374 (8%)
Query: 9 ESEIVN--LHEIPPRKGSYGSFK--FRHEEVNKLVEELGF-KLYSHQVEALKLLYSGKNV 63
E +IV LH P + YG+ E +N L K Y HQ +A+ L++G +V
Sbjct: 270 EGQIVQEALHTYPAVEAQYGALSRPLSQELINALYTSRNIEKTYKHQADAINHLWNGFHV 329
Query: 64 VVSTPTASGKSEIFRLFIFDEFLEDSSSTFLLIYPTRALINNQLEKFERENEIFSKI-TG 122
+VST T+SGKS I+++ I LED+ ST ++PT++L +Q + +I S + T
Sbjct: 330 IVSTSTSSGKSLIYQIPILQSLLEDNQSTAFFVFPTKSLAQDQKKSLI---DILSYMPTL 386
Query: 123 RKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDYKWLFKNLKLLVVDE 182
+ + GD L R I R N+IFT PDMLH +LP + + FKNLKL V+DE
Sbjct: 387 KNIRVDTFDGDTPLESRESIIRSA-NIIFTNPDMLHQTILPNANRWYYFFKNLKLFVLDE 445
Query: 183 LHIYRGVFGSNVAYVFRRLFLRLRRLKVNP--RILALSATLKNPKDFAEKFFGFE-FEEV 239
H+Y G+FG +VA+V RR+ R+ N R ++ SAT+++P +K FG + + +
Sbjct: 446 AHVYNGIFGVHVAFVLRRM-RRIAEYFGNSQYRFVSCSATIEDPLQHMKKIFGVDNIKLI 504
Query: 240 TEAGNPSPKRYIIMFEPT----------RFSGEQLIRQIVERLVENDVKTLVFFDSRKGT 289
+PS + +M+ P + S +++ + E V+T+VF RK
Sbjct: 505 NYTSSPSGSKKFVMWNPPYVDPKHPDDGKKSAISEASKLLIKFAEKRVRTIVFCRVRKTC 564
Query: 290 ERIMRMF---LGSK----VFNLITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGI 342
E +MR+ L +K + + I +Y+ T ER +IES+ GKL ++ TNALELGI
Sbjct: 565 ESLMRLVRQELKTKQKGDLLSKIQSYRAGYTVQERRKIESEMFNGKLYGIIATNALELGI 624
Query: 343 DVGDLDAVINYGIP 356
D+G LDAVI G P
Sbjct: 625 DIGSLDAVITIGFP 638
>pir||B70564 hypothetical protein Rv3649 - Mycobacterium tuberculosis (strain
H37RV) >gi|2105045|emb|CAB08839.1| (Z95436) hypothetical
protein Rv3649 [Mycobacterium tuberculosis]
Length = 771
Score = 185 bits (465), Expect = 2e-45
Identities = 135/430 (31%), Positives = 218/430 (50%), Gaps = 31/430 (7%)
Query: 9 ESEIVNLHEIPPRKGS-YGSFKFRHEEVNKLVEELGFKL-YSHQVEALKLLYSGKNVVVS 66
E + ++ E+PP+ G G ++ +V + G +SHQ EA +L Y+G++VV+
Sbjct: 20 ERPLRHVAELPPQAGRPRGWPEWAEPDVVDAFADRGISSPWSHQAEAAELAYAGRHVVIG 79
Query: 67 TPTASGKSEIFRLFIFDEFLEDSSSTFLLIYPTRALINNQLEKFERENEIFSKITGRKVG 126
T ASGKS ++L + + DS + L + PT+AL ++QL ++ V
Sbjct: 80 TGPASGKSLAYQLLVLNALATDSRARALYLSPTKALGHDQLRAAHALAAAVPRLAD--VA 137
Query: 127 NSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDYKWLFKNLKLLVVDELHIY 186
+ GD E RR RE+ +F+ P+M H ++L + L +NL+ ++VDE H Y
Sbjct: 138 PTAYDGDSP-DEVRRFARERSRWLFSNPEMTHLSVLRNHARWAVLLRNLRFVIVDECHYY 196
Query: 187 RGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKDFAEKFFGFEFEEVTEAGNPS 246
RGVFGSNVA V RRL R +P ++ SAT +P A G EVTE G+P
Sbjct: 197 RGVFGSNVAMVLRRLLRLCARYSAHPTVIFASATTASPGATAADLIGQPVVEVTEDGSPR 256
Query: 247 PKRYIIMFEPT--------------RFSGEQLIRQIVERLVENDVKTLVFFDSRKGTE-- 290
R + ++EP R +G + R + + +VE +TL F SR+ E
Sbjct: 257 GARTVALWEPALRSDVIGEHGAPVRRSAGAEAARVMADLIVEG-AQTLTFVRSRRAAELT 315
Query: 291 ----RIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGIDVGD 346
R + + ++ + + +Y+ +R + EG+L+ L TTNALELG+D+
Sbjct: 316 ALGARARLVDIAPELSDTVASYRAGYLAEDRSALHQALAEGQLRGLATTNALELGVDIAG 375
Query: 347 LDAVINYGIPSDGLFSLIQRFGRAGRDPNRVAINGIVLRRNGLDYYYKEHFEELVE-GIE 405
LDAV+ G P + S Q+ GR+GR + A+ ++ R + LD Y H L++ +E
Sbjct: 376 LDAVVLAGFPGT-VASFWQQAGRSGR-RGQGALVVLIARDDPLDTYLVHHPAALLDKPVE 433
Query: 406 KGLVEGIPVN 415
+ +++ PVN
Sbjct: 434 RVVID--PVN 441
Score = 87.4 bits (213), Expect = 6e-16
Identities = 44/111 (39%), Positives = 61/111 (54%), Gaps = 1/111 (0%)
Query: 759 VKSGLHAIEHNLIKIAPVVTHVDSRELGGYSYDDF-NGLPTIFIYDGNEGGSGIARLIYE 817
+ LHA EH I + P+V D ++GG S GLP++F+YDG GG+G A +
Sbjct: 653 IPGSLHAAEHAAIGLLPLVASCDRGDIGGMSTATGPEGLPSVFVYDGYPGGAGFAERGFR 712
Query: 818 NIEKLIVRSREHIAKCPCKDGCPACVYSPKCGTFNEFLDKWMAIKIWDKVL 868
+ + E I C C GCP+CV SPKCG N+ LDK A+++ VL
Sbjct: 713 RARTWLGATAEAIEACECPSGCPSCVQSPKCGNGNDPLDKAGAVRVLRLVL 763
>pir||T36671 probable helicase - Streptomyces coelicolor
>gi|4539568|emb|CAB38487.1| (AL035636) putative helicase
[Streptomyces coelicolor A3(2)]
Length = 815
Score = 171 bits (429), Expect = 3e-41
Identities = 169/632 (26%), Positives = 271/632 (42%), Gaps = 66/632 (10%)
Query: 10 SEIVNLHEIPPRKGSYGSFKFR-HEEVNKLVEELGFKL-YSHQVEALKLLYSGKNVVVST 67
+ I + +PPR G + + R EV V G + ++HQ + G +VVV+T
Sbjct: 53 ARITHTEHLPPRAGRHAVWPDRIRPEVLAAVRAAGIEHPWAHQARVAEHALDGDSVVVAT 112
Query: 68 PTASGKSEIFRLFIFDEFLEDSSS------TFLLIYPTRALINNQLEKFERENEIFSKIT 121
TASGKS + + + ++ S + T L + PT+AL +Q + S+
Sbjct: 113 GTASGKSLAYLVPVLSALVDGSEAPNGRGATTLYLAPTKALAADQCRSVKE----LSQPL 168
Query: 122 GRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDYKWLFKNLKLLVVD 181
G V ++ GD ER IR+ V+ T PDMLH +LP + K LK +V+D
Sbjct: 169 GTSVRAAVYDGDTPFEEREWIRQYGTYVL-TNPDMLHRGILPSHPRWSSFLKALKYVVID 227
Query: 182 ELHIYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKDFAEKFFGFEFEEVTE 241
E H YRGVFGS+VA V RRL R +P L SAT P A + G EV +
Sbjct: 228 ECHTYRGVFGSHVAQVLRRLRRLCARYGASPVFLLASATAAEPSVAARRLTGLPVIEVAD 287
Query: 242 AGNPSPKRYIIMFEP--TRFSGEQ----------LIRQIVERLVENDVKTLVFFDSRKGT 289
+P + ++EP T GE+ ++ L ++++ F SR+G
Sbjct: 288 DASPRGELVFALWEPPLTELEGEKGAPVRRTATAEAADLLTDLTVQGMRSITFVRSRRGA 347
Query: 290 ERIMRMF------LGSKVFNLITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGID 343
E I + + + + Y+G ER +E G L L TNALELG+D
Sbjct: 348 ELISVIAQERLAEVDRSLAGRVAAYRGGYLPEERRALERALHSGDLLGLAATNALELGLD 407
Query: 344 VGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNRVAINGIVLRRNGLDYYYKEHFEELVEG 403
+ LDAV+ G P SL Q+ GRAGR + A+ +V R + LD + H E L +
Sbjct: 408 ISGLDAVVIAGYPGTRA-SLWQQAGRAGR-AGQGALAVLVARDDPLDTFLVHHPEALFD- 464
Query: 404 IEKGLVEGIPVNLDNERIAKKHLHYLLSELGVVDVNEIPEHWRIALRPLKEEGIVEEYLN 463
VE ++ DN + HL +EL + + LK G E L
Sbjct: 465 ---QPVESTVLDPDNPYVLAPHLCAAAAELPLTE------------EDLKLFGPACEELL 509
Query: 464 PLTNKVEIRIKKPAIYSSIRSTSDESFFLVKDEGWIRSSLVRKSGGELLRFVNYLKARGF 523
P ++ ++ + R ++ EG +V + G LL
Sbjct: 510 PQLEAAKLLRRRTRAWHWTRRERAADLTDIRGEGGRPVQVVEEGTGRLL----------- 558
Query: 524 IIEEVDEVEFYRSLLPGMVYPSRGRLFMVIDKINVDKFHFVFAQEIPMNEDVETNVHKSE 583
VD + ++ G V+ +GR ++V ++++ + Q P T +
Sbjct: 559 --GTVDAGAAHTTVHEGAVHLHQGRTYLV-RSLDLEDSVALVEQATPA---YSTVARDTT 612
Query: 584 NVEVLKVQDEKSFGPIKVYFGRLKVTHEYLGY 615
+ VL+ E +G ++ +G ++VT++ + +
Sbjct: 613 AISVLETDIEVPWGDGRLCYGSVEVTNQVVSF 644
Score = 84.3 bits (205), Expect = 5e-15
Identities = 41/103 (39%), Positives = 58/103 (55%), Gaps = 2/103 (1%)
Query: 763 LHAIEHNLIKIAPVVTHVDSRELGGYSYDDFNG--LPTIFIYDGNEGGSGIARLIYENIE 820
LHA EH I + P+ D ++GG S LPT+F+YDG+ GG+G A +
Sbjct: 695 LHAAEHASIGMLPLFATCDRWDIGGVSVPLHPDTLLPTVFVYDGHPGGAGFAERAFHTAR 754
Query: 821 KLIVRSREHIAKCPCKDGCPACVYSPKCGTFNEFLDKWMAIKI 863
+ +RE IA C C GCP+C+ SPKCG N+ L K A+++
Sbjct: 755 DWLTATREAIASCECDAGCPSCIQSPKCGNGNDPLHKRGAVRL 797
>gb|AAK40384.1| ATP-dependent helicase [Sulfolobus solfataricus]
Length = 739
Score = 165 bits (413), Expect = 2e-39
Identities = 138/475 (29%), Positives = 228/475 (47%), Gaps = 30/475 (6%)
Query: 3 DVFKGLESEIVNLHE---IPPRKGSYGSFKFRHEEVNKLVEELGF-KLYSHQVEALKLLY 58
D K ++I ++H + P G + +++ K + E G +LY +Q +A + +
Sbjct: 9 DKLKTFNAKIAHVHTETFLEPEYGPSINEIDIDDKLKKSIIEYGIERLYKYQYDAYRKIK 68
Query: 59 SGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFLLIYPTRALINNQLEKFERENEIFS 118
+ +NV++ + T +GK+E F + I D L+ S +L+YPT+AL +QL + + +
Sbjct: 69 NKENVMIISGTGTGKTEAFLIPILDLALKGERS--VLVYPTKALARDQLTRVYK----LA 122
Query: 119 KITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDYKWLFKNLKLL 178
+ G VG I GD ER R+ R P+++ T PDM+H L +++L +
Sbjct: 123 RELGLNVG--IFDGDTPEKERERLYRNPPHILITNPDMIHLGLALS-TRFRFLLRTADHF 179
Query: 179 VVDELHIYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKDFAEKFFGFEFEE 238
+ DE+H+Y GV G+++ R L R++ K + I+A SAT+ K E+ FG E E
Sbjct: 180 IFDEVHVYEGVLGAHI----RNLADRIKEFKNDIHIVASSATVGATKYLFEELFGVEGEI 235
Query: 239 VTEAGNPSPKRYIIMFEPTRFSGEQLIRQIVERLVENDVKTLVFFDSRKGTERIMRMFLG 298
+ + + S L + LV+N +K LVF DS++ E + ++
Sbjct: 236 IEGIRRRKGIAIHSIIDSGNSSRWTLAAYLAAVLVKNGLKVLVFTDSQQMAELVAKIADR 295
Query: 299 SKVFNLITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSD 358
+V + ++ L ER ++E R G+L ++ T LELGID+G +DAVI P
Sbjct: 296 FRVN--LEVHRAGLIAEERIKVEEKLRNGELDGVVATPTLELGIDIGTIDAVIMAENP-P 352
Query: 359 GLFSLIQRFGRAGRDPNRVAINGIVLRRNGLDYYYKEHFEELVEGIEKGLVEGIPVNLDN 418
+QR GRAGR N + +L + +D YY H EE ++ + + N
Sbjct: 353 SYTKYVQRAGRAGR-RNNAGLVFTILGDDPIDSYYLRHPEEFF----TRKIQALTFDPTN 407
Query: 419 ERIAKKHLHYLLSELGVVDVNEIPEHWRIALRPLKEEG---IVEEYL--NPLTNK 468
+ K H L+E V +N +P W+ A L E IV Y+ P T K
Sbjct: 408 IEVIKIHALAYLAEKYRVKLNNLPPLWKKAYEILATESRAKIVGSYVLATPETKK 462
Score = 84.7 bits (206), Expect = 4e-15
Identities = 39/105 (37%), Positives = 63/105 (59%), Gaps = 4/105 (3%)
Query: 764 HAIEHNLIKIAPVVTHVDSRELGGYSYDDFNGLPTIFIYDGNEGGSGIARLIYENIEKLI 823
HA EH LI A V +LGG SY + + IYD + GGSG+++L++E +E+
Sbjct: 622 HATEHVLISAARVAAGASLTDLGGISYPSGH----VVIYDSSIGGSGVSKLLFERLEQAY 677
Query: 824 VRSREHIAKCPCKDGCPACVYSPKCGTFNEFLDKWMAIKIWDKVL 868
+ + + C C+DGCP CVYSP CG N++L + ++++ D ++
Sbjct: 678 EVALDIVKSCNCEDGCPNCVYSPYCGNNNKYLSRKKSLRLIDGLI 722
>pir||H75564 probable ATP-dependent helicase - Deinococcus radiodurans (strain
R1) >gi|6457724|gb|AAF09654.1|AE001869_3 (AE001869)
ATP-dependent helicase, putative [Deinococcus
radiodurans]
Length = 872
Score = 165 bits (413), Expect = 2e-39
Identities = 132/436 (30%), Positives = 209/436 (47%), Gaps = 46/436 (10%)
Query: 45 KLYSHQVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFLLIYPTRALIN 104
++Y+HQ + +L+++GKNV+++TPTASGK+ F +F+ + +T L +YP AL
Sbjct: 56 EVYAHQADTYRLMHAGKNVIITTPTASGKTGAFFPAVFERLEQKPEATALFVYPLVALGQ 115
Query: 105 NQLEKFE--RENEIF----SKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLH 158
+Q +K RE F + G + TG+V + + TPD LH
Sbjct: 116 DQRDKLRAFREKGGFGWDIAAFHGSAQPGDVFTGNVRM-------------VTATPDKLH 162
Query: 159 YNL-LPRWLDYKWLFKNLKLLVVDELHIYRGVFGSNVAYVFRRLFLRLRRLKVNPRILAL 217
+ L P D+ + L+ +V+DE H YRG FGS VA + RRL R L NP+++
Sbjct: 163 WALDKPAVRDF---LRRLEFIVLDEAHTYRGGFGSEVAGMLRRLLDLARALGANPQVVLS 219
Query: 218 SATLKNPKDFAEKFFGFEFEEVTEAGNP-SPKRYII---MFEPTRFSGEQLIRQIVERLV 273
+AT+ NP +FA + G E E+V E+G KRY + +P RF +V +
Sbjct: 220 TATIGNPAEFARELVGVEAEQVGESGAARHGKRYYLADHRGQPRRFWD-----SVVSASI 274
Query: 274 ENDVKTLVFFDSRKGTERIMRMFLGSKVF--NLITTYKGTLTKLERWRIESDFREGKLKA 331
+D+K L FF R R+ + + ++ GT + R S+FR K
Sbjct: 275 HHDLKVLAFFRGRSRAARLYSTYRSQSRYAPHVHLYMAGTSDREGRL---SEFRRTKSGV 331
Query: 332 LLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNRVAINGIVLRRNG--- 388
+ TNALE G+D+GDL+ VI G P + + Q GRAGR + + L G
Sbjct: 332 MFATNALEAGVDIGDLEVVIIDGYPGSRM-AFRQMAGRAGRVAPGLVLYLPALNEQGVPQ 390
Query: 389 -LDYYYKE--HFEELVEG-IEKGLVEGIPVNLDNERIAKKHLHYLLSELGVVDVNEIPEH 444
+D +Y +F EL+ G +EK +VE L A+++ + + L + P +
Sbjct: 391 PVDAFYSNLGNFRELLTGPLEKAVVEAGNPYLSPRHQARRNAEFRAAGLPALP-RPGPSY 449
Query: 445 WRIALRPLKEEGIVEE 460
W + ++EE
Sbjct: 450 WNLRGEGSATFAVIEE 465
>gb|AAB99596.1| (U67597) M. jannaschii predicted coding region MJ1572.1
[Methanococcus jannaschii]
Length = 112
Score = 158 bits (396), Expect = 2e-37
Identities = 69/112 (61%), Positives = 87/112 (77%), Gaps = 5/112 (4%)
Query: 763 LHAIEHNLIKIAPVVTHVDSRELGGYSYDDFN-----GLPTIFIYDGNEGGSGIARLIYE 817
+HAIEHN+IKI P+ T++DSRE+GGYSY+ FN IFIYDGNEGG G+A ++YE
Sbjct: 1 MHAIEHNIIKITPIFTYIDSREIGGYSYERFNRNLFKDKAVIFIYDGNEGGFGLAEILYE 60
Query: 818 NIEKLIVRSREHIAKCPCKDGCPACVYSPKCGTFNEFLDKWMAIKIWDKVLN 869
N EKL+ +S EH+ C C DGCP C+YS KCGTFNEFLDKW AI+I +K+L+
Sbjct: 61 NAEKLLNKSLEHLKNCNCADGCPLCIYSTKCGTFNEFLDKWQAIRILEKLLS 112
>gi|11499982 ATP-dependent RNA helicase, putative [Archaeoglobus fulgidus]
>gi|7446072|pir||G69550 ATP-dependent RNA helicase
homolog AF2406 - Archaeoglobus fulgidus
>gi|2650686|gb|AAB91259.1| (AE001109) ATP-dependent RNA
helicase, putative [Archaeoglobus fulgidus]
Length = 766
Score = 155 bits (389), Expect = 1e-36
Identities = 127/417 (30%), Positives = 208/417 (49%), Gaps = 32/417 (7%)
Query: 45 KLYSHQVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFLLIYPTRALIN 104
+LY Q EA+ L G++VV++ PT GK+E F + + L + ++ YPT+AL
Sbjct: 85 RLYPFQKEAMIRLMEGRDVVITAPTGFGKTEAFAVPMLWRALHGGKA--MVFYPTKALAR 142
Query: 105 NQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPR 164
+Q EK + ++ G + GD ERR + K ++I T PDM+ Y+L
Sbjct: 143 DQEEKIK----FYTSSLGLRAVR--FDGDSGREERRAVLSGKCDIILTNPDMVDYHLR-N 195
Query: 165 WLDYKWLFKNLKLLVVDELHIYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNP 224
++ + + L + VDELH Y GV GSN+ Y+ +RL R + I SATL N
Sbjct: 196 TPAFRRICRELSFIAVDELHTYTGVLGSNMHYLVKRLS-RFAEFQ----IACASATLSNA 250
Query: 225 KDFAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIRQIVERLVENDVKTLVFFD 284
+FAE+ F +F V+ I + P+ +S +R+IV L + K +VF +
Sbjct: 251 AEFAEELFDRDFVLVSGEHRKGTLHLIFRYTPSLYSA---VREIVTAL--RNRKIIVFGN 305
Query: 285 SRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGIDV 344
S K E I + + + I +K L K R +E+ F+ G++ +++T LELG+D+
Sbjct: 306 SYKSVETINLILRRHGLKSAI--HKSGLPKEVREEVEAKFKRGEINIVVSTPTLELGVDI 363
Query: 345 GDLDAVINYGIPSDGLFSLIQRFGRAGRDPNRVAINGIVLRR-NGLDYYYKEHFEELVEG 403
GD+D V++ +P +IQR GRAGR + ++ ++LR + + YY+ E+ +
Sbjct: 364 GDVDVVVSELVPYG---QMIQRVGRAGR-KGQESVGVVILREDDSISTYYRTKPEDYFKE 419
Query: 404 IEKGLVEGIPVNLDNERIAKKHLHYLLSELGVVDVNEIPEHWRIALRPLKEEGIVEE 460
G VE NE + K L + E V + E+ ++ L+ +GIV E
Sbjct: 420 EANGYVE-----RHNEEVMKFQLISMCIE-KPVRLEELDRQSAEIMQKLQAQGIVVE 470
Score = 82.7 bits (201), Expect = 2e-14
Identities = 47/147 (31%), Positives = 79/147 (52%), Gaps = 12/147 (8%)
Query: 726 HYIRAVIRKVAKEEGLDENFVFAVK--KMVDSKDGVKSGLHAIEHNLIKIAPVVTHVDSR 783
HY+ + K +G F+F+ D +D HA+EH +I+ +T SR
Sbjct: 606 HYLDEPVSYTFKTKG----FLFSAPFPDPADYEDYYAGSFHALEHVIIETTDAITGGGSR 661
Query: 784 ELGGYSYDDFNGLPTIFIYDGNEGGSGIARLIYENIEKLIVRSREHIAKCPCK--DGCPA 841
E+GG S + + IF+YD + GGSG+++L+++ + + S+ + C C DGCP
Sbjct: 662 EMGGISVPEGD----IFVYDASVGGSGLSKLLFKRLRRAFEISKTILESCDCGRVDGCPK 717
Query: 842 CVYSPKCGTFNEFLDKWMAIKIWDKVL 868
C YS +CG N+ L++ A+ I +KV+
Sbjct: 718 CTYSYQCGNNNQPLNRIGALNIAEKVI 744
>gi|11500031 large helicase-related protein (lhr-2) [Archaeoglobus fulgidus]
Length = 862
Score = 115 bits (285), Expect = 2e-24
Identities = 147/614 (23%), Positives = 274/614 (43%), Gaps = 106/614 (17%)
Query: 35 VNKLVEELGFKLYSH----QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSS 90
++ LV E YS Q A+ + G+NV++++PT SGK+ L +E +
Sbjct: 17 LHPLVREWFLSKYSEFTPPQKYAIVEAFKGRNVLITSPTGSGKTLAAFLAAISMLVEKAE 76
Query: 91 STFL-------LIYPTRALINNQLEKFERE--NEIFSK-----ITGRKVGNSILTGDVEL 136
L + P +AL NN + K E EI++ I +K+ ++ TGD +
Sbjct: 77 KGELEDRVYVVYVSPLKAL-NNDIRKNLEEPLEEIYALAEKKGIKLQKIRAAVRTGDTDA 135
Query: 137 SERRRIRREKPNVIFTTPDMLHYNLLPRWLDYKWLFKNLKLLVVDELHIYRGVFGSNVAY 196
+E+++ R+ P+++ TTP+ L L + N++ L+VDE+H N
Sbjct: 136 AEKQKQARKPPHILITTPETLAIVLCSP--KFSKSLTNVRFLIVDEIH----AIAENKRG 189
Query: 197 VFRRLFL-RLRRLKVNPRI-LALSATLKNPKDFAEKFFGFEFEE-----VTEAGNPSPKR 249
V L + RL+R++ + + LSAT+ ++ A G+ + E + + P
Sbjct: 190 VHLTLSMERLQRIQEGEMVRIGLSATISPLEEIARFLVGYNYGEERDCVIADVTFEKPMD 249
Query: 250 YIIMFEPTRF---SGEQLIRQIVERLVE---NDVKTLVFFDSRKGTERIMRMFLGSKVFN 303
++ F S E++ ++ + L E + TL+F ++R TER++
Sbjct: 250 IKVVSPINDFFSASAEEISDRLYDLLAEYVKSSKTTLIFTNTRSATERVVYHLKKRLKDF 309
Query: 304 LITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSL 363
I + +L+K R +E++ + G+L+ ++++ +LELGID+G +D VI G P +
Sbjct: 310 PIKAHHSSLSKEVRLEVENELKNGELRCVVSSTSLELGIDIGYIDLVILLGSPK-SINRA 368
Query: 364 IQRFGRAGRDPNRVAINGIVLRRNGLDYYYKEHFEELVEGIEKGLVEGIPVNLDNERIAK 423
+QR GR+G + V++ IV+ ++LVE E LD +I +
Sbjct: 369 LQRIGRSGHRLHEVSVGRIVVVDQ----------DDLVECTVLA-KEARERRLDRVKIPR 417
Query: 424 KHLHYLLSELGVVDVNEIPEHWRI--ALRPLK-----EEGIVEEYLNPLT----NKVEIR 472
K L L + + + ++ W + AL ++ E EE+L+ L N E+
Sbjct: 418 KCLDVLCQHVVGMAIEKV---WSVDEALALIRNAYPYRELTREEFLSVLRYLSGNFSELE 474
Query: 473 IKKPAIYSSIRSTSDESFFLVKDEGWIRSSLVRKSGGELLRFVNYLKARGFIIEEVD--- 529
KK +Y+ I +E F G+++R + YL G I +EV
Sbjct: 475 KKK--VYAKIWFDEEEGVF--------------GRRGKMIRPIYYLNT-GTIPDEVAVKV 517
Query: 530 -----------EVEFYRSLLPGMVYPSRGRLF---------MVIDKINVDK--FHFVFAQ 567
E EF +LLPG ++ G+ F ++++++ +K F++
Sbjct: 518 ITKDGKRVGKVEEEFAENLLPGDIFVLAGKTFRFLKAKGMSIIVEEVEGEKPTVPSWFSE 577
Query: 568 EIPMNEDVETNVHK 581
++P++ D+ + K
Sbjct: 578 QLPLSYDLAERIRK 591
>gi|11498749 large helicase-related protein (lhr-1) [Archaeoglobus fulgidus]
>gi|7446074|pir||D69393 large helicase-related protein
(lhr-1) homolog - Archaeoglobus fulgidus
>gi|2649437|gb|AAB90094.1| (AE001024) large
helicase-related protein (lhr-1) [Archaeoglobus
fulgidus]
Length = 892
Score = 113 bits (279), Expect = 1e-23
Identities = 140/575 (24%), Positives = 253/575 (43%), Gaps = 91/575 (15%)
Query: 50 QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLE-DSSSTFLLIY--PTRALINNQ 106
Q+EA + + SGK+V++ PT SGK+E + IF+ L+ + + IY P RAL +
Sbjct: 22 QLEAFRKILSGKDVLIIAPTGSGKTEAAIIPIFEAMLKMEKPEGIVAIYITPLRALNRDM 81
Query: 107 LEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWL 166
L + ++ G +V + GD S+R R R+ P+++ TTP+ L + L
Sbjct: 82 LRRIRG----IAEFLGIRV--DVRHGDTPDSQRARQSRKPPHLLITTPETFQILFLGKNL 135
Query: 167 DYKWLFKNLKLLVVDELHIY----RGVFGSNVAYVFRRLFLRLRRLKVNPRI--LALSAT 220
+ KN++ +VVDE+H RGV +L + L RL+ R + LSAT
Sbjct: 136 --RKALKNVRYVVVDEIHELIDSERGV----------QLSVALERLREMARFQTIGLSAT 183
Query: 221 LKNPKDFAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQL---------IRQIVER 271
+ PK +F G + E + + ++ E +L ++ I +
Sbjct: 184 VSRPK-LVSRFVGADAEVLEWKAEKEYEIEVVKPEVDEKLAAKLGVDAEIAGELKFIADA 242
Query: 272 LVENDVKTLVFFDSRKGTERIMRMFLGSKVFNLITT--YKGTLTKLERWRIESDFREGKL 329
+ E+ L+F ++R+ E LG K+ LI + G+L++ R E F +G+L
Sbjct: 243 VKEHG-SALIFVNTRQTAEA-----LGIKLKKLIDVEVHHGSLSRETRVEAEERFAKGEL 296
Query: 330 KALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNRVAINGIVLRRNGL 389
AL+ T+++ELGID+G ++ V+ Y P + L+QR GR+G RV+
Sbjct: 297 DALICTSSMELGIDIGHVNLVVQYNSPRQAV-RLVQRVGRSGHGLGRVS----------K 345
Query: 390 DYYYKEHFEELVEG------IEKGLVEGIPVNLDNERIAKKHLHYLLSELGVVDVNEIPE 443
Y F++++E ++GL+E ++ + + + L E G +D +
Sbjct: 346 GYVVASSFDDILESAVIVRRAKEGLLEDAEIHFKSFDVLANQICALALEYGRIDAEKA-- 403
Query: 444 HWRIALRPLKEEGIVEEYLNPLTN------KVEIRIKKPAIYSSIRSTSDESFFLVKDEG 497
RI R + E + + N K+ + + R E+ ++ DE
Sbjct: 404 -HRIVKRAFPYRNLTFEEFDEVCNFLARIGKIFYDEGEIGARRNTRRYFYENISMIPDEK 462
Query: 498 WIRSSLVRKSGGELLRFVNYLKARGFIIEEVDEVEFYRSLLPGMVYPSRGRLFMVIDKIN 557
R +V S G+ + ++ E + S G ++ +G L+ V+
Sbjct: 463 HYR--VVDVSSGKTIGSLD---------------ESFLSTFSGEIFAMKGELWRVLSVDE 505
Query: 558 VDKFHFVFAQ-EIP--MNEDVETNVHKSENVEVLK 589
V + V A+ EIP + E++ ++ V +L+
Sbjct: 506 VVRVEPVSAEGEIPSWVGEEIPVPFEVAQEVGMLR 540
>gb|AAK40723.1| ATP-dependent helicase [Sulfolobus solfataricus]
Length = 913
Score = 112 bits (278), Expect = 2e-23
Identities = 108/406 (26%), Positives = 201/406 (48%), Gaps = 38/406 (9%)
Query: 39 VEELGFK-LYSHQVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFLLIY 97
+++LG++ L Q A+ + SGKNV++ PT GK+E L IF +D +Y
Sbjct: 12 LKKLGYEDLTPIQKIAIPKVLSGKNVLIIAPTGYGKTEAAILPIFYTIFKDKPEKISTLY 71
Query: 98 --PTRALINNQLE-KFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTP 154
P RAL N LE + R E F+ + ++ GD ER+ I P+V+ TP
Sbjct: 72 ITPLRAL-NRDLELRLRRLGEAFN------ISVNVRHGDSSQKERKEILDNPPDVLLVTP 124
Query: 155 DMLHYNLLPRWLDYKWLFKNLKLLVVDEL-HIYRGVFGSNVAYVFRRLFLRLRRLKVNPR 213
+ L Y +L ++ F NLK +++DEL + G ++ + +R+ R K+ +
Sbjct: 125 ETLLYLVLND--TFRKYFTNLKWIIIDELQEMLDEKRGIELSVLIQRIKKIATRNKI--Q 180
Query: 214 ILALSATLKNPKDFAEKFFGFEFEEVTEAGNPSP----KRYIIMFEPTRFSGEQLIR--- 266
++ +SAT+ + A+++ E E E N + K +I+ + + + ++
Sbjct: 181 LIGISATI-GDVEIAKRYLDREGE--VEIANINAIKDIKVDLILPKVEKKDADLAVKLGL 237
Query: 267 --------QIVERLVENDVKTLVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERW 318
+ + +++N+ ++F ++R+ +E I + + I ++ G+L++ R
Sbjct: 238 RPDTIARLEKLNEIIKNNKPIIIFTNTRETSEFIANQLMSNYSLK-IASHHGSLSREIRI 296
Query: 319 RIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNRVA 378
+ E+DF+ G + A++ T++LELGID+G ++ V+ Y P + LIQR GR+G R +
Sbjct: 297 KTENDFKNGNIDAIVATSSLELGIDIGRINLVVQYMSPRQ-VIRLIQRVGRSGHKIGRTS 355
Query: 379 INGIVLRRNGLDYY-YKEHFEELVEG-IEKGLVEGIPVNLDNERIA 422
I ++ + D + E L G +EK L E P+++ IA
Sbjct: 356 IGYVIPSEDLFDILECRAIIEALYSGYLEKPLFEENPLDVAAHEIA 401
>pir||D75091 large helicase-related protein (lhr-2) PAB0744 - Pyrococcus abyssi
(strain Orsay) >gi|5458545|emb|CAB50033.1| (AJ248286)
large helicase-related protein (lhr-2) [Pyrococcus
abyssi]
Length = 867
Score = 112 bits (278), Expect = 2e-23
Identities = 142/598 (23%), Positives = 260/598 (42%), Gaps = 113/598 (18%)
Query: 53 ALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLE-------DSSSTFLLIYPTRALIN- 104
A+ ++ G+NV++S+PT SGK+ L I E + + + + P RAL N
Sbjct: 43 AIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGKLEDKIYCVYVSPLRALNND 102
Query: 105 ---NQLEKFERENEIFSKITGR--KVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHY 159
N E + E+ ++ ++ ++ T D E+ ++ + P+++ TTP+ L
Sbjct: 103 IRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKSKMLKMPPHILITTPESLAI 162
Query: 160 NL-LPRWLDYKWLFKNLKLLVVDELH-IYRGVFGSNVAYVFRRLFLRLRRLKVNPRILAL 217
L PR ++ +++K ++VDE+H + GS++A RL +R V + L
Sbjct: 163 ALNAPR---FREKLRDVKWVIVDEVHALAENKRGSHLALTLERLRELTKRDFVR---IGL 216
Query: 218 SATLKNPKDFAEKFFGFEFEEVTEAGNPSPKRYI------------------IMFEPTRF 259
SAT+ ++ A+ FGF ++ G P P + +++ P
Sbjct: 217 SATIHPLEEVAKFVFGF-----SDDGKPRPGLIVDVSFAKKTKITVESVVEDLVYTPANV 271
Query: 260 SGEQLIRQIVERLVENDVKTLVFFDSRKGTERIMRMFLGSKVF----NLITTYKGTLTKL 315
E L R+I E LV + TL+F ++R G ER+ K+F + I + +L++
Sbjct: 272 LNEALYRRIGE-LVRSRKTTLIFTNTRSGAERVAYHL--KKMFPEWEDKIEAHHSSLSRE 328
Query: 316 ERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPN 375
R +E + G+LK ++++ +LELGID+G +D VI G P + +QR GRAG +
Sbjct: 329 VRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPK-SVNRALQRIGRAGHRLH 387
Query: 376 RVAINGIVLRRNGLDYYYKEHFEELVEGIEKGLVEGIPVNLDNERIAKKHLHYLLSEL-- 433
V+ G++L LD L K LD +I K L L+ L
Sbjct: 388 EVS-EGVIL---ALDRDDLVEVTVLAHNARKR-------KLDRIKIPKNPLDVLVQHLLG 436
Query: 434 -GVVDVNEIPEHWRIALRPLKEEGI-VEEYLNPLTNKVE--IRIKKPAIYSSIRSTSDES 489
+ V E+ E +++ R + E+++N L +++ +Y+ I
Sbjct: 437 MALERVWEVEEAYKVVRRAYPYHDLPFEDFINVLKYLAGEFSGLEERKVYAKI------- 489
Query: 490 FFLVKDEGWIRSSLVRKSGGELLRFVNYLKARGFIIEEVD--------------EVEFYR 535
W+ + K G++ R + Y+ G I +E E EF
Sbjct: 490 --------WLENGKFGKR-GKMTRAIYYMNT-GTIPDEAKIDVFTMDKKYIGTVEEEFAE 539
Query: 536 SLLPGMVYPSRGRLFMVIDKINVDKFHFV------------FAQEIPMNEDVETNVHK 581
L+PG ++ GR + + K +K + + F++ +P++ D+ ++ K
Sbjct: 540 RLIPGDIFVLAGRTYEFV-KSRGNKIYVIPREGVKPTIPSWFSEMLPLSFDLALDIQK 596
>emb|CAC11727.1| (AL445064) hypothetical protein [Thermoplasma acidophilum]
Length = 1690
Score = 112 bits (278), Expect = 2e-23
Identities = 108/373 (28%), Positives = 185/373 (48%), Gaps = 41/373 (10%)
Query: 28 FKFRHEEVNKLVEELGFKLYSHQVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLE 87
F F V+K L Q A+ L++SG+NV+VS+PT +GK+ L I +E +
Sbjct: 14 FPFLDTHVSKWFNSNYSSLTEPQKYAIPLIHSGRNVLVSSPTGTGKTMTAFLTIINELVS 73
Query: 88 DSSSTFL-------LIYPTRALIN--NQLEKFERENEIFSKITGR-----KVGNSILTGD 133
+ L I P +AL N N+ KF + I+S + +V S+ +GD
Sbjct: 74 LAKEGRLEDRVYCVYISPLKALANDINKNLKFPLDG-IYSIMDSEGIKVPRVRISVRSGD 132
Query: 134 VELSERRRIRREKPNVIFTTPDMLHYNLL-PRWLDYKWLFKNLKLLVVDELH-IYRGVFG 191
SER+++ R+ P+++ TTP+ L P+ + +N++ +++DE+H I G
Sbjct: 133 TTESERQKMVRKPPHILITTPESFSLALSSPKMREN---LRNVRYVIIDEIHEISSTKRG 189
Query: 192 SNVAYVFRRLFLRLRRLKVNPRI--LALSATLKNPKDFAEKFFGFEFE--------EVTE 241
S ++ RL L ++P + + LSAT ++ A+ GFE E EV
Sbjct: 190 SLLSANLERLNL------ISPGMVRIGLSATQSPIEEIAKYLVGFEGEKARPCEIVEVRG 243
Query: 242 AGNPSPKRYIIMFEPTRFSGE---QLIRQIVERLVENDVKTLVFFDSRKGTERIMRMFLG 298
+ + + + TR S E + I+ LV+ TL+F ++R GTE + M L
Sbjct: 244 EKHLDLRTITPVPDLTRVSYEVANDRMYDIIADLVKQYRTTLIFTNTRSGTEHVA-MRLK 302
Query: 299 SKVFNLITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSD 358
S+ + + ++ K +R +E+ + G+L+ ++T+ +LELGID+G +D VI G P
Sbjct: 303 SRGIESLEAHHSSMGKDQRLEVENKLKNGELRCVITSTSLELGIDIGFIDLVIQIGSPK- 361
Query: 359 GLFSLIQRFGRAG 371
+ +QR GR+G
Sbjct: 362 SVSKGLQRIGRSG 374
>pir||C71004 probable ATP-dependent helicase - Pyrococcus horikoshii
>gi|3257752|dbj|BAA30435.1| (AP000006) 912aa long
hypothetical ATP-dependent helicase [Pyrococcus
horikoshii]
Length = 912
Score = 111 bits (276), Expect = 3e-23
Identities = 103/363 (28%), Positives = 181/363 (49%), Gaps = 51/363 (14%)
Query: 32 HEEVNKLVEELGFKLYSHQVEALKLLYS-GKNVVVSTPTASGKSEIFRLFIFDEFLEDSS 90
H + K ++E KL Q++A K +Y G++V++ PT SGK+E + + + L+D+
Sbjct: 2 HIVLKKAIKEKFGKLNKLQIQAFKAIYGEGESVLIIAPTGSGKTEAAIIPVINSILKDNL 61
Query: 91 STFLLIY--PTRALINNQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPN 148
+Y P +AL + LE+ + E TG KV + GD S R + + P+
Sbjct: 62 RPISCLYIAPLKALNRDLLERLKWWGEK----TGIKV--EVRHGDTPQSMRAKQVKNPPH 115
Query: 149 VIFTTPDMLHYNLLPRWLDYKWLFKNLKLLVVDELHIY----RGVFGSNVAYVFRRLFLR 204
++ TTP+ L L + L K+L +N+K ++VDE+ RG+ +L L
Sbjct: 116 ILITTPESLPAILTTKSLR-KYL-ENVKFVIVDEITELVDNKRGI----------QLILN 163
Query: 205 LRRLKVNPRIL--ALSATLKNPKDFAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGE 262
L+RL + + LSAT+ N ++ E FE + + + ++ +++ + +
Sbjct: 164 LKRLSLIADFIRIGLSATVGNEEEIRE---WFEAKRIIKPHLKKRYKFKVLYPQPKPEDQ 220
Query: 263 QLIRQI------------VERLVENDVKTLVFFDSRKGTERIMRMFLGSKVFNL---ITT 307
+L ++ + +VE K L+F ++R+ E LG ++ +
Sbjct: 221 ELAEKLKVPGDVATRLRTLWEIVEKYKKALIFVNTRQFAE-----ILGHRLKTWGKPVEV 275
Query: 308 YKGTLTKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRF 367
+ G+L+K R E +EGK+KAL+ T+++ELGID+GD+D VI Y P + LIQR
Sbjct: 276 HHGSLSKEARIEAERKLKEGKIKALICTSSMELGIDIGDVDVVIQYMSPRQ-VNRLIQRA 334
Query: 368 GRA 370
GR+
Sbjct: 335 GRS 337
>pir||T35049 probable ATP-dependent helicase - Streptomyces coelicolor
>gi|3483040|emb|CAA20551.1| (AL031371) putative
ATP-dependent helicase [Streptomyces coelicolor A3(2)]
Length = 731
Score = 111 bits (275), Expect = 3e-23
Identities = 107/363 (29%), Positives = 177/363 (48%), Gaps = 39/363 (10%)
Query: 35 VNKLVEELGFK-LYSHQVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLED--SSS 91
++ +V LG+ L Q A+ L G++ V+ PTA GK+E + E + +
Sbjct: 24 LHHIVNTLGWSDLRPLQRAAITPLMEGEDAVLLAPTAGGKTEAACFPLLSAMAEQKWTGT 83
Query: 92 TFLLIYPTRALINNQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIF 151
+ L + P +AL+NN + + + +++ GR+ ++ GD + S+R+RIR E P+V+
Sbjct: 84 SVLYLCPLKALLNNLVSRVDT----YTQWLGRRA--ALWHGDTKESQRQRIRTEAPDVLL 137
Query: 152 TTPDMLHYNLLPRWLDYKWLFKNLKLLVVDELHIYRGVFGSNVAYVFRRLFLRLRRLKVN 211
TTP+ L L+ D+ L +++ +VVDE+H + G + + + RL ++
Sbjct: 138 TTPESLEAMLIGVKTDHARLLGSVRAVVVDEVHAFA---GDDRGWHLLAVLERLEQVTGR 194
Query: 212 P-RILALSATLKNPKDFAEKFFGFEFEEVTEAGN-PSPKRYIIMFE-------PT----- 257
P + + LSAT+ NP + G E T AG +P + FE PT
Sbjct: 195 PIQRIGLSATVGNPDQLLDWLQGAGVE--TRAGRVVAPGVTLPAFEAVGSDRKPTAEEVP 252
Query: 258 RFSGEQLIRQI--------VERLVENDVKTLVFFDSRKGTERIMRMFLGSKVFNLITTYK 309
R +GE + + + + K LVF DSR E++ +V ++
Sbjct: 253 RPAGEVELDYVGSLDNAAKLIATLHRGEKRLVFCDSRAQVEQLGAALRAREVTVFLS--H 310
Query: 310 GTLTKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGR 369
+L+ ER R E F E + +++T+ LELGIDVGDLD VI P+ + S +QR GR
Sbjct: 311 ASLSVDERTRSEQAFAEARDCVIVSTSTLELGIDVGDLDRVIQIDSPAT-VASFLQRIGR 369
Query: 370 AGR 372
GR
Sbjct: 370 TGR 372
>sp|Q57742|HELX_METJA PUTATIVE ATP-DEPENDENT HELICASE MJ0294 >gi|2129094|pir||G64336
large helicase related protein LHR homolog -
Methanococcus jannaschii >gi|1591016|gb|AAB98279.1|
(U67484) large helicase-related protein (LHR), probably
RNA helicase [Methanococcus jannaschii]
Length = 841
Score = 111 bits (275), Expect = 3e-23
Identities = 138/610 (22%), Positives = 277/610 (44%), Gaps = 101/610 (16%)
Query: 53 ALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSST-------FLLIYPTRALINN 105
A+K ++ GKNV++ +PT SGK+ L +E ++ S L + P RAL NN
Sbjct: 42 AIKEIHEGKNVLICSPTGSGKTLSAFLAGINELIKLSMENKLEDRIYILYVSPLRAL-NN 100
Query: 106 QLEKFERE--NEIF--SKITGRKVGN---SILTGDVELSERRRIRREKPNVIFTTPDMLH 158
+E+ +E EI+ +K G ++ ++ T D S+++R+ ++ P+++ TTP+ L
Sbjct: 101 DIERNLKEPLKEIYDVAKEIGIELDEIRVAVRTSDTTSSQKQRMLKKPPHILITTPESLA 160
Query: 159 YNL-LPRWLDYKWLFKNLKLLVVDELHIYRGVFGSNVAYVFRRLFLRLRRLKVNPRILAL 217
L P+ + L +K ++VDE+H G +++ RL +++ L
Sbjct: 161 IALNSPK---FSQLLSGIKYVIVDEIHALTNKRGVHLSLSLERLNRIANFIRIG-----L 212
Query: 218 SATLKNPKDFAEKFFG---------FEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIRQI 268
SAT+ + A+ G +++ E SP I + P+ ++L +
Sbjct: 213 SATIHPLTEVAKFLVGNGRDCYIVDVSYKKEIEIKVISPVDDFI-YTPSEEISKRLYN-L 270
Query: 269 VERLVENDVKTLVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFREGK 328
+++L+E TL+F ++R TER+ +L + T+ +L++ R +E ++G+
Sbjct: 271 LKKLIEEHKTTLIFTNTRSATERVA-FYLKQLGVEKVETHHSSLSREHRLEVEEKLKKGE 329
Query: 329 LKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNRVAINGIVLRRNG 388
++ +++ +LELG+D+G +D VI G P + +QR GR+G + + GI++ +
Sbjct: 330 IRVCISSTSLELGVDIGSIDLVILLGSPK-SVSRALQRIGRSGHRLHEKS-KGIIIPFDR 387
Query: 389 LDYYYKEHFEELVEGIEKGLVEGIPVNLDNERIAKKHLHYLLSEL---GVVDVNEIPEHW 445
++LVE + I +D I K L L L + V ++ E +
Sbjct: 388 ---------DDLVENVVLAYDAKIG-KIDRIHIPKNCLDVLAQHLVGMALEKVWDVDEAY 437
Query: 446 RIALRPLKEEGIVEEYLNPLTNKVEIRIKKPAIYSSIRSTSDESFFLVKDEGWIRSSLVR 505
+ + + + ++ + N + I++ +Y+ I W++ +
Sbjct: 438 NLIKKAYPYKDLSKKDFLDVLNYLAGGIEEKNVYAKI---------------WLKDNKFG 482
Query: 506 KSGGELLRFVNYLK-------------ARGFIIEEVDEVEFYRSLLPGMVYPSRGRLFMV 552
K G+ +R + Y+ A G + EV+E EF L+ G ++ G+ +
Sbjct: 483 KR-GKSVRAIYYMNVGTIPDETAVDVIADGKYVGEVEE-EFAEKLMKGDIFVLGGKTYKY 540
Query: 553 I----DKINVDK-------FHFVFAQEIPMNEDVETNVHK------SENVEVLKVQ---D 592
+ +KI V + F++++P+ D+ ++ K S ++E ++ + D
Sbjct: 541 LGGRGNKIRVKEVFDEKPTIPAWFSEQLPLAYDLALDIEKFRKEVLSSDIEEIREKYDID 600
Query: 593 EKSFGPIKVY 602
EK+ IK Y
Sbjct: 601 EKTAKAIKNY 610
>gb|AAK40467.1| ATP-dependent helicase [Sulfolobus solfataricus]
Length = 875
Score = 110 bits (273), Expect = 6e-23
Identities = 100/363 (27%), Positives = 178/363 (48%), Gaps = 38/363 (10%)
Query: 50 QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFL-------LIYPTRAL 102
Q A+ L+ NV+VS+PT SGK+ L I D E + L I P RAL
Sbjct: 35 QRAAIPLIKQNYNVLVSSPTGSGKTLAAFLGILDSLFELGDNNELEDKVYAIYISPLRAL 94
Query: 103 IN----NQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLH 158
N N LE ++ SK+ +VG I T D E++++ ++ P+++ TTP+
Sbjct: 95 NNDMQRNLLEPLNELRQVNSKLPDVRVG--IRTSDTTPYEKQKMLKKPPHILITTPESFG 152
Query: 159 YNLLPRWLDYKWLFKNLKLLVVDELHIY----RGVFGSNVAYVFRRLFLRLRRLKVNPRI 214
++ K ++K ++VDE+H RG + S + +FR L + +++
Sbjct: 153 ISITSPKFSQK--LTDVKWIIVDEIHELANSKRGAYLSAMLELFRNLITKKEFVRIG--- 207
Query: 215 LALSATLKNPKDFAEKFFGFEFE-EVTEAG--NPSPKRYIIMFEPTRFSGEQLIRQIVER 271
LSAT+ ++ A+ G + E + +A P + I + S E + + + +
Sbjct: 208 --LSATVSPLEEVAQFLVGKDREYRIVDARFVKPVDIKVISPVKDLVHSSESEVDKGIYK 265
Query: 272 LVENDVK----TLVFFDSRKGTERIM----RMFLGSKVFNL--ITTYKGTLTKLERWRIE 321
+ N+VK TL+F ++R TER+ ++ KVF++ I + +L++ R +E
Sbjct: 266 TILNEVKKHRTTLIFTNTRHATERVAYKLRKLAENEKVFDVDAIEAHHSSLSRDVRLDVE 325
Query: 322 SDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNRVAING 381
++G LK ++++ +LELGID+G +D VI P + L+QR GRAG ++
Sbjct: 326 EKLKKGILKVVVSSTSLELGIDIGYIDLVILLSSPK-SVSRLLQRIGRAGHHIRSISKGR 384
Query: 382 IVL 384
+++
Sbjct: 385 VIV 387
>sp|P95949|HELX_SULSO PUTATIVE ATP-DEPENDENT HELICASE C04010 >gi|7446117|pir||S75377
probable helicase LHR - Sulfolobus solfataricus
>gi|1707782|emb|CAA69580.1| (Y08257) ATP-dependent
helicase [Sulfolobus solfataricus]
Length = 875
Score = 110 bits (273), Expect = 6e-23
Identities = 100/363 (27%), Positives = 178/363 (48%), Gaps = 38/363 (10%)
Query: 50 QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFL-------LIYPTRAL 102
Q A+ L+ NV+VS+PT SGK+ L I D E + L I P RAL
Sbjct: 35 QRAAIPLIKQNYNVLVSSPTGSGKTLAAFLGILDSLFELGDNNELEDKVYAIYISPLRAL 94
Query: 103 IN----NQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLH 158
N N LE ++ SK+ +VG I T D E++++ ++ P+++ TTP+
Sbjct: 95 NNDMQRNLLEPLNELRQVNSKLPDVRVG--IRTSDTTPYEKQKMLKKPPHILITTPESFG 152
Query: 159 YNLLPRWLDYKWLFKNLKLLVVDELHIY----RGVFGSNVAYVFRRLFLRLRRLKVNPRI 214
++ K ++K ++VDE+H RG + S + +FR L + +++
Sbjct: 153 ISITSPKFSQK--LTDVKWIIVDEIHELANSKRGAYLSAMLELFRNLITKKEFVRIG--- 207
Query: 215 LALSATLKNPKDFAEKFFGFEFE-EVTEAG--NPSPKRYIIMFEPTRFSGEQLIRQIVER 271
LSAT+ ++ A+ G + E + +A P + I + S E + + + +
Sbjct: 208 --LSATVSPLEEVAQFLVGKDREYRIVDARFVKPVDIKVISPVKDLVHSSESEVDKGIYK 265
Query: 272 LVENDVK----TLVFFDSRKGTERIM----RMFLGSKVFNL--ITTYKGTLTKLERWRIE 321
+ N+VK TL+F ++R TER+ ++ KVF++ I + +L++ R +E
Sbjct: 266 TILNEVKKHRTTLIFTNTRHATERVAYKLRKLAENEKVFDVDAIEAHHSSLSRDVRLDVE 325
Query: 322 SDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNRVAING 381
++G LK ++++ +LELGID+G +D VI P + L+QR GRAG ++
Sbjct: 326 EKLKKGILKVVVSSTSLELGIDIGYIDLVILLSSPK-SVSRLLQRIGRAGHHIRSISKGR 384
Query: 382 IVL 384
+++
Sbjct: 385 VIV 387
>pir||B75127 large helicase-related protein (lhr-1) PAB1817 - Pyrococcus abyssi
(strain Orsay) >gi|5458242|emb|CAB49731.1| (AJ248285)
large helicase-related protein (lhr-1) [Pyrococcus
abyssi]
Length = 912
Score = 109 bits (270), Expect = 1e-22
Identities = 104/358 (29%), Positives = 176/358 (49%), Gaps = 42/358 (11%)
Query: 32 HEEVNKLVEELGFKLYSHQVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSS 91
H + K ++E +L Q+EA K + GK+V++ PT SGK+E L + + L+D
Sbjct: 2 HILLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLP 61
Query: 92 TFLLIY--PTRALINNQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNV 149
+Y P +AL + LE+ + + TG ++ + GD R + R P+V
Sbjct: 62 PISCLYIAPLKALNRDLLERLKW----WEAKTGIRI--DVRHGDTTQYRRAKQVRNPPHV 115
Query: 150 IFTTPDMLHYNLLPRWLDYKWL---FKNLKLLVVDEL-HIYRGVFGSNVAYVFRRLFLRL 205
+ TTP+ L P L K L KN++ +VVDE+ + G+ + +RL L
Sbjct: 116 LITTPETL-----PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIA 170
Query: 206 RRLKVNPRILALSATLKNPKDFAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQL- 264
+++ LSAT+ N ++ E +E+ + ++ ++F R ++L
Sbjct: 171 DFIRIG-----LSATVGNEEEVKE---WLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELA 222
Query: 265 --IRQIVE---------RLVENDVKTLVFFDSRKGTERIM-RMFLGSKVFNLITTYKGTL 312
+R VE +VE + LVF ++R+ E + R+ K + + G+L
Sbjct: 223 ELLRVDVEVAARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKP---VEVHHGSL 279
Query: 313 TKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRA 370
+K R E +EGK+KAL+ T+++ELGID+G++DAVI Y P + LIQR GR+
Sbjct: 280 SKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQ-VNRLIQRAGRS 336
>pir||G72526 hypothetical protein APE2188 - Aeropyrum pernix (strain K1)
>gi|5105887|dbj|BAA81199.1| (AP000063) 977aa long
hypothetical protein [Aeropyrum pernix]
Length = 977
Score = 107 bits (264), Expect = 7e-22
Identities = 96/349 (27%), Positives = 169/349 (47%), Gaps = 27/349 (7%)
Query: 35 VNKLVEELGFK-LYSHQVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSST- 92
V +L+ E G+K L Q +A ++Y G N +V PT SGK+E + ++
Sbjct: 39 VLELLREAGYKSLLPIQEKAFPIIYRGLNALVVAPTGSGKTEAALAPLLARLRNGRVASG 98
Query: 93 ----FLLIYPTRALINNQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPN 148
+ + P RAL + + ER +F + GD S RRR P+
Sbjct: 99 GGVKVVYVTPLRALNRDLEGRVERLAGLFGYTV------QVRHGDTVQSSRRRFLERPPD 152
Query: 149 VIFTTPDMLHYNLLPRWLDYKWLFKNLKLLVVDELH-IYRGVFGSNVAYVFRRLFLRL-R 206
++ TTP+ L L + K + K + +VVDE+H + G ++ +L L R
Sbjct: 153 IVITTPESLALLLTVKRA--KEVLKQARAVVVDEIHELMESKRGVELSLNLEKLELMAGR 210
Query: 207 RLKVNPRILALSATLKNPKDFAEKFFGFEFEEVTEAGNPSPKRY----IIMFEPTRFSGE 262
RL+ + LSAT+ + V+ + SPK Y +++ + RF E
Sbjct: 211 RLQR----IGLSATVSRHSLYRAASLLGAGRHVSMVLDTSPKEYDVRVVVVGDEGRF-WE 265
Query: 263 QLIRQIVERLVENDVKTLVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIES 322
++ I E LV+ + +++ F + + T + L ++ + + G+L++ R R+E
Sbjct: 266 NSVKAIAE-LVKGEGGSVLIFANTRSTVETLAFALSRELGEEVPAHHGSLSRHVRERVER 324
Query: 323 DFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAG 371
DF+EG++KA++ T++LELGIDVG + V+ + P + +++QR GR+G
Sbjct: 325 DFKEGRVKAIVATSSLELGIDVGRVALVVQFLSPRQ-VTAMVQRAGRSG 372
>gb|AAG19610.1| (AE005050) ATP-dependent helicase; HelA [Halobacterium sp. NRC-1]
Length = 946
Score = 107 bits (264), Expect = 7e-22
Identities = 106/384 (27%), Positives = 175/384 (44%), Gaps = 43/384 (11%)
Query: 23 GSYGSFKFRHEEVNKLVEELGFKLYSH-QVEALKLLYSGKNVVVSTPTASGKSEIFRLFI 81
G +F EV + E GF + Q A+ L G+N +V PT +GK+E L +
Sbjct: 7 GRMDAFTHLGSEVRNALSERGFTTPTEPQRRAVPALADGRNGLVVAPTGTGKTETAMLPV 66
Query: 82 FDEFLEDSSST----FLLIYPTRALINNQLEKFERENEIFSKITGRKVGNSILTGDVELS 137
FD + D L + P RAL + E+ + E G +V + GD
Sbjct: 67 FDALVSDGGPPDGFGALYVTPLRALNRDMRERLDWWGETL----GLEV--DVRHGDTTDY 120
Query: 138 ERRRIRREKPNVIFTTPDMLHYNLLPRWLDYKWLFKNLKLLVVDELHIYRGVF-GSNVAY 196
+RR+ + P+V+ TTP+ L L L + +++ +VVDE+H G G+ +A
Sbjct: 121 QRRQQATDPPDVLVTTPETLQAMLTGSTL--RDGLADVEHVVVDEVHELAGAKRGAQLAI 178
Query: 197 VFRRLFLRLRRLKVNPRI--LALSATLKNPKDFAEKFFGFEFEEVTEAGNPSPKRYIIMF 254
RL ++V R+ + LSAT+ +P + G E+ E S + +
Sbjct: 179 GLERL------VEVAGRVQRIGLSATVGDPHEIGAFLTGGRGCEIIEVDVTSNVSFEVRE 232
Query: 255 EPTRFSGEQLIRQI------------VERLVENDVKTLVFFDSRKGTERIMRMFLGSKVF 302
+ E+L ++ + +V+ L+F ++R+ E LGS+
Sbjct: 233 PAVTDADERLASELLTTPAMASHVRAIREIVDRHDSVLIFVNTRQTAEA-----LGSRFK 287
Query: 303 NL---ITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDG 359
L I + G+L+K R +E F+ G L LL T+++ELGIDVG +D V+ Y P +
Sbjct: 288 ELDANIGVHHGSLSKDARIDVEDRFKSGDLDGLLCTSSMELGIDVGGIDHVVQYNSPRE- 346
Query: 360 LFSLIQRFGRAGRDPNRVAINGIV 383
+ L+QR GRAG + V+ ++
Sbjct: 347 VKRLLQRVGRAGHSRDAVSEGTVI 370
>emb|CAC11967.1| (AL445065) Large helicase related protein [Thermoplasma
acidophilum]
Length = 894
Score = 106 bits (262), Expect = 1e-21
Identities = 110/413 (26%), Positives = 187/413 (44%), Gaps = 53/413 (12%)
Query: 27 SFKFRHEEVNKLVEELGFKLYSH-QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEF 85
SF + E + ++ + G + Q + + L+ GKNV++ +PT SGK+E L +F
Sbjct: 4 SFSYLDERIIAMLRDRGITDPTDPQEQIIPLVLEGKNVLLLSPTGSGKTEAAVLPVFQRI 63
Query: 86 LEDSSSTFLLIY--PTRALINNQLEKFERENEIFSKIT--GRKVGNSILT--GDVELSER 139
L + +Y P RAL +I S++ GR++G + D+ +++
Sbjct: 64 LREKPKKVFALYITPLRAL----------NRDILSRLVDYGRELGIDVQVRHSDMSDADK 113
Query: 140 RRIRREKPNVIFTTPDMLHYNLLPRWLDYKWLFKNLKLLVVDELH-IYRGVFGSNVAYVF 198
RR+ P+++ TTP+ L +L + + N+++++VDELH GS ++
Sbjct: 114 RRMAESPPDILVTTPESL--QILLNGKNLRRFIANVRVVIVDELHDAAENERGSQLSLAL 171
Query: 199 RRLFLRLRRLKVNPRILALSATLKNPKDFAEKFF---GFEFEEVTEAGNPSPKRYIIMFE 255
RLR L N + + LSAT+ NP D A E T N S I +
Sbjct: 172 E----RLRDLAGNFQRIGLSATVGNPGDLARFLVPNGTCEIISTTLKKNMS----IDVMV 223
Query: 256 PTRFSGEQLIRQIVER-----------LVENDVKTLVFFDSRKGTERI---MRMFLGSKV 301
P S E +R L+ +LVF + R E + +++ G
Sbjct: 224 PDESSEEDAEVMGCDRQYAGAILKVWDLINRHAGSLVFVNRRFVAEDLAFRLKLKFGEIP 283
Query: 302 FNLITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLF 361
+ + G+L+K R E F+ G++KAL+ T++LELGIDVG +AVI + P +
Sbjct: 284 ---VLVHHGSLSKETREFAERSFKNGEVKALICTSSLELGIDVGTANAVIQFNSPRQ-IN 339
Query: 362 SLIQRFGRAGRDPNRVAINGIVLRRNGLDYYYKEHFEELVEGIEKGLVEGIPV 414
+IQR GR+ + + +V D E +V+ I +G +E + +
Sbjct: 340 KMIQRIGRSEHWIGKTSKGYVVC----TDVIEMEEAIAIVDSIAEGKIENVQI 388
>pir||A69140 ATP-dependent helicase - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2621366|gb|AAB84818.1| (AE000816)
ATP-dependent helicase [Methanobacterium
thermoautotrophicum]
Length = 702
Score = 101 bits (248), Expect = 5e-20
Identities = 93/347 (26%), Positives = 162/347 (45%), Gaps = 39/347 (11%)
Query: 38 LVEELGFK-LYSHQVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFLLI 96
L LG++ L Q AL+ + G++ ++ PTASGK+E + +F+ L + ++
Sbjct: 14 LANRLGWRSLRDVQKSALEAIGRGEDTLIVAPTASGKTEAALIPVFNSILSEGLPPVSML 73
Query: 97 Y--PTRALINNQLEKFERENEIFSKITGRKVGNSILT--GDVELSERRRIRREKPNVIFT 152
Y P +ALIN+ + E + G ++ GDV + +RR + +++
Sbjct: 74 YVSPLKALINDMHSRLE--------LWGNHFNLEVMKWHGDVPANRKRRFIKNPSDILLI 125
Query: 153 TPDMLHYNLLPRW-LDYKWLFKNLKLLVVDELHIYRGVFGSNVAYVFRRLFLRLRRLK-V 210
TP+ L ++ R + + + NL+ ++VDE+H + ++ L RL R V
Sbjct: 126 TPESLEVMMINRSRAEKERILGNLRYIIVDEIHQF---IEADRGVQLNSLLARLERYTGV 182
Query: 211 NPRILALSATLKNPKDFAEKFF--GFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIRQI 268
P+ + LSAT+ NP++ G + E K +FE +++R+
Sbjct: 183 RPQRIGLSATVGNPEEVLNWMSPSGAVVRDTAER-----KLQYRIFELNHHKLIEVLRRF 237
Query: 269 VERLVENDVKTLVFFDSRKGTER---IMRMFLGSKVFNLITTYKGTLTKLERWRIESDFR 325
+ K L+F SR+ E+ I+R L VF + ++ + R E FR
Sbjct: 238 TGK------KVLIFVPSRRDAEKYYNIIRKCLDVDVF----IHHSSINRDSREEAEERFR 287
Query: 326 EGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGR 372
++ T+ LELGIDVGD+D VI+ P+ + +QR GR+GR
Sbjct: 288 SVSAAFMVNTSTLELGIDVGDIDVVIHIRSPT-SVNRFLQRTGRSGR 333
>pir||C72521 hypothetical protein APE2144 - Aeropyrum pernix (strain K1)
>gi|5105843|dbj|BAA81155.1| (AP000063) 880aa long
hypothetical protein [Aeropyrum pernix]
Length = 880
Score = 98.3 bits (241), Expect = 3e-19
Identities = 99/357 (27%), Positives = 175/357 (48%), Gaps = 40/357 (11%)
Query: 50 QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFL-------EDSSSTFLLIYPTRAL 102
Q +A+ L+ GK+V++++PT +GK+ L + DE L E+ + + P RAL
Sbjct: 21 QRQAIPLVKQGKSVLITSPTGTGKTLAAFLGVIDEILFLMENRWEEKGILAVYVSPLRAL 80
Query: 103 INN---QLEKFERENEIFSKITGR---KVGNSILTGDVELSERRRIRREKPNVIFTTPDM 156
N+ LE+ R E ++ G +V ++ T D E++++ ++ P+++ TTP+
Sbjct: 81 NNDIRRNLEEPLRGIEEKAREMGLEPPRVKVAVRTSDTTPYEKQKMVKDPPHILITTPES 140
Query: 157 LHYNLLPRWLDYKWLFKNLKLLVVDELH-IYRGVFGSNVAYVFRRLFLRLRRLKVNP-RI 214
L L ++ +K +V+DE+H + G+++ RL +R P R
Sbjct: 141 LAAALAAP--KFRERLSTVKWVVLDEIHELASNKRGAHLMVSVERLEELVREAGGKPLRR 198
Query: 215 LALSATLKNPKDFAEKFFG-FEFE------EVTEA--GNPSPKRYI-----IMFEPTRFS 260
+ LSAT+ P D F G F+ E + +A P + I ++ +P
Sbjct: 199 IGLSATIA-PLDVVANFLGGFDDEGRPREVHIVDARFAKPIDIKVITPDVDLLRDPPDKI 257
Query: 261 GEQLIRQIVERLVENDVKTLVFFDSRKGTERIMRMFL------GSKVFNLITTYKGTLTK 314
E + R+I E LV+ TL+F ++R TER++ G + I + +L++
Sbjct: 258 NEAIYRKIAE-LVKQHRTTLIFTNTRSATERVVHKLKQILVKEGIASEDQIEAHHSSLSR 316
Query: 315 LERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAG 371
R +E + G+LK ++++ +LELGID+G +D VI P + L+QR GRAG
Sbjct: 317 NLRLDVEERLKRGELKVVVSSTSLELGIDIGYIDLVILLSSPK-SVSRLLQRVGRAG 372
>gb|AAK41239.1| ATP-dependent helicase [Sulfolobus solfataricus]
Length = 933
Score = 97.5 bits (239), Expect = 6e-19
Identities = 97/350 (27%), Positives = 167/350 (47%), Gaps = 28/350 (8%)
Query: 33 EEVNKLVEELGF-KLYSHQVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSS 91
+ + KL+EE + KL Q + + + +G N +V PT GK+E L I + L++
Sbjct: 7 QRLRKLIEEKNWMKLTRVQEMSFEPISNGYNTLVIAPTGYGKTEAALLPILNRMLKEDVK 66
Query: 92 TFLLIY--PTRALINNQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNV 149
+IY P +ALIN+ L + + + RK G+V E+ + P++
Sbjct: 67 PVTVIYITPLKALINDLLYRIDWWASRLGFLVNRK------HGEVPQKEKNLRLKRIPHI 120
Query: 150 IFTTPDMLHYNLLPRWLD-YKWLFKNLKLLVVDELH-IYRGVFGSNVAYVFRRLFLRLRR 207
I TTP+ L +L W ++ +KN+K +VVDE+H + G+ ++ + RL +
Sbjct: 121 IVTTPEGLEIDL--DWASRFREHYKNVKWVVVDEIHELINSKRGTQLSILLERLKYFIG- 177
Query: 208 LKVNPRILALSATLKNPKDFAEKFFGFEFEEVTEAGNPSPKRYIIMFEP----TRFSGEQ 263
+ + + LSAT+ + A+ FG ++ + + I F+ +
Sbjct: 178 --YDFQRIGLSATVSDEDKVAQFLFGSSERKMKIIRLNDTRNFEIKINKLGNDNSFALWK 235
Query: 264 LIRQIVERLVENDVKTLVFFDSRKGTERIMRMF--LGSKVFNLITTYKGTLTKLERWRIE 321
+ + +L+E TLVF +SR TER+ LG+K I + ++++ + E
Sbjct: 236 SAAEKINQLIEKP--TLVFTNSRFSTERLHEELEKLGNKE---IYVHHSSVSRDLKNLAE 290
Query: 322 SDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAG 371
+ R G KA++ T LELGI VGD+ VI P + S +QR GR+G
Sbjct: 291 GELRNGNAKAVVCTKTLELGIHVGDIKKVIMLR-PPTSVSSFLQRLGRSG 339
>sp|O27830|HELX_METTH PUTATIVE ATP-DEPENDENT HELICASE MTH1802 >gi|7446115|pir||H69107
ATP-dependent helicase - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622934|gb|AAB86268.1| (AE000934) ATP-dependent
helicase [Methanobacterium thermoautotrophicum]
Length = 862
Score = 95.6 bits (234), Expect = 2e-18
Identities = 97/363 (26%), Positives = 166/363 (45%), Gaps = 41/363 (11%)
Query: 53 ALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEF--------LEDSSSTFLLIYPTRALIN 104
A+ ++ G+NV+VS+PT SGK+ L I E LEDS + I P +AL N
Sbjct: 40 AIMDIHRGRNVLVSSPTGSGKTLTAFLSIISELTRLADDGELEDSVYC-IYISPLKALDN 98
Query: 105 NQLEKFERENEIFSKIT---GR--KVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHY 159
+ E I GR ++ ++ TGD ER R+ ++ P+++ TTP+ L
Sbjct: 99 DIERNLEEPLSAIRDIAAGEGRDLEIRKAVRTGDTTSYERSRMLKKPPHILITTPETLSI 158
Query: 160 NLLPRWLDYKWLFKNLKLLVVDELHIYRGVFGSNVAYVFRRLFL-RLRRLKVNPRILALS 218
L+ ++ ++ ++VDE+H N V L L RL+ L + + LS
Sbjct: 159 LLVAP--KFREKLSTVRYVIVDEIHS----LADNKRGVHLSLSLERLQHLVGDFTRIGLS 212
Query: 219 ATLKNPKDFAEKFFGFEFEEVTEA-------------GNPSPKRYIIMFEPTRFSGEQLI 265
AT+ + A G+ + E P I+ +P +
Sbjct: 213 ATVHPLERVARFLVGYSYGSERECLIVDVSYLKELDIDLICPVDDIVAADPEEIGNA--L 270
Query: 266 RQIVERLVENDVKTLVFFDSRKGTERIM----RMFLGSKVFNLITTYKGTLTKLERWRIE 321
I+ L+E+ TL+F ++R GTE ++ F S + I + +L++ R E
Sbjct: 271 YDILHDLIEDHRTTLIFTNTRSGTESVVYNLKSRFPESYSDSNIMAHHSSLSREIRLETE 330
Query: 322 SDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNRVAING 381
+ G+LKA++++ +LELGID+G +D V+ P + +QR GR+G ++ +
Sbjct: 331 EKLKRGELKAVVSSTSLELGIDIGYIDLVVLLSSPK-SVSRALQRIGRSGHQLHQRSKGR 389
Query: 382 IVL 384
IV+
Sbjct: 390 IVV 392
>pir||F83237 probable ATP-dependent DNA helicase PA3272 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9949397|gb|AAG06660.1|AE004749_9 (AE004749) probable
ATP-dependent DNA helicase [Pseudomonas aeruginosa]
Length = 1448
Score = 93.6 bits (229), Expect = 8e-18
Identities = 90/351 (25%), Positives = 152/351 (42%), Gaps = 36/351 (10%)
Query: 50 QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDS---------SSTFLLIYPTR 100
QVEA + G + +V+ PT SGK+ L D + + ++ + + P +
Sbjct: 40 QVEAWPAIREGLSTLVAAPTGSGKTLTAFLAAIDALVVEGLAAGGELADATQVVYVSPLK 99
Query: 101 ALINNQLEKFE------RENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTP 154
AL N+ E RE + + +++ TGD ER +R+ P+++ TTP
Sbjct: 100 ALSNDIRINLEQPLAGIREELARLGLPDVDIRSAVRTGDTPQVERGAMRKRPPHILVTTP 159
Query: 155 DMLHYNLLPRWLDYKWLFKNLKLLVVDELHIYRGVF-GSNVAYVFRRLFLRLRRLKVNPR 213
+ L+ L + + ++ ++VDE+H G GS++A RL + L P
Sbjct: 160 ESLYILLGSE--SGRQMLAGVRSVIVDEIHALAGSKRGSHLALSLERL----QALCPRPL 213
Query: 214 I-LALSATLKNPKDFAEKFFGFEFE------EVTEAGNPSPKRYIIMFEPTRFSGE---- 262
+ + LSAT K + A G + + G P+ I P
Sbjct: 214 LRIGLSATQKPIEKVARFLVGASGNPRDPACRIVDVGYTRPRDLGIEVPPVALEAVMSND 273
Query: 263 --QLIRQIVERLVENDVKTLVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRI 320
+L+ + L TLVF ++R+ ER+ R + + G+L K R
Sbjct: 274 TWELVYDRLAHLAGEHRTTLVFVNTRRMAERVTRFLAERLGSRQVAAHHGSLAKELRLDA 333
Query: 321 ESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAG 371
E + G+LK L+ T +LELGID+GD++ V P + + +QR GR+G
Sbjct: 334 EQRLKAGQLKVLVATASLELGIDIGDVELVCQLSSPR-SIAAFLQRVGRSG 383
>gi|9755332 C4 zinc finger DNA-binding protein of low sequence specificity in
vitro; Probable 119 kD DNA/RNA helicase family member;
Hfm1p [Saccharomyces cerevisiae]
Length = 1187
Score = 87.4 bits (213), Expect = 6e-16
Identities = 110/456 (24%), Positives = 188/456 (41%), Gaps = 88/456 (19%)
Query: 26 GSFKFRHEEVNKLVEELGFKLYSHQVEALKLLY-SGKNVVVSTPTASGKSEIFRLFIFDE 84
G FKF E NK+ Q EA +Y S +N ++S+PT SGK+ +F L I
Sbjct: 132 GVFKFT--EFNKM-----------QSEAFPSIYESNENCIISSPTGSGKTVLFELAILRL 178
Query: 85 FLEDSSST----FLLIYPTRALINNQLEKFERENEIFSKITGRKVGNSILTGDVELSERR 140
E +S T + I PT++L +E F VG +LT D E
Sbjct: 179 IKETNSDTNNTKIIYIAPTKSLC------YEMYKNWFPSFVNLSVG--MLTSDTSFLETE 230
Query: 141 RIRREKPNVIFTTPDMLHYNLLPRWLDYKWLFKNLKLLVVDELHIYRGVFGSNVAYVFRR 200
+ + K N+I TTP+ L RW DY LF+ +KL++VDE+H + G+++ +
Sbjct: 231 KAK--KCNIIITTPEKWDL-LTRRWSDYSRLFELVKLVLVDEIHTIKEKRGASLEVI--- 284
Query: 201 LFLRLRRLKVNPRILALSATLKNPKD-----------------FAEKFFGFEFEEVTEAG 243
R+ + N R +ALSAT+ N +D F E + + +
Sbjct: 285 -LTRMNTMCQNIRFVALSATVPNIEDLALWLKTNNELPANILSFDESYRQVQLTKFVYGY 343
Query: 244 NPSPKRYIIMFEPTRFSGEQLIRQIVERLVENDVKTLVFFDSRKGTERIMRMFLGSKVFN 303
+ + K F+ +LI +I+E+ +N L+F +R T + L + +F+
Sbjct: 344 SFNCKN---DFQKDAIYNSKLI-EIIEKHADNR-PVLIFCPTRASTISTAKFLLNNHIFS 398
Query: 304 L---------------------ITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGI 342
I + ++ +R +E +F G + L +T+ L +G+
Sbjct: 399 KSKKRCNHNPSDKILNECMQQGIAFHHAGISLEDRTAVEKEFLAGSINILCSTSTLAVGV 458
Query: 343 DVGDLDAVI-------NYGIPSDGLFSLIQRFGRAGRDPNRVAINGIVLRRNGLDYYYKE 395
++ +I + I ++Q GRAGR +++ D K+
Sbjct: 459 NLPAYLVIIKGTKSWNSSEIQEYSDLDVLQMIGRAGRPQFETHGCAVIM----TDSKMKQ 514
Query: 396 HFEELVEGIEKGLVEGIPVNLDNERIAKKHLHYLLS 431
+E L+ G + L + +NL A+ L + S
Sbjct: 515 TYENLIHGTDV-LESSLHLNLIEHLAAETSLETVYS 549
>sp|P51979|HFM1_YEAST HFM1 PROTEIN >gi|780546|gb|AAA93159.1| (U22156) Hfm1p
[Saccharomyces cerevisiae]
Length = 1048
Score = 86.6 bits (211), Expect = 1e-15
Identities = 103/432 (23%), Positives = 180/432 (40%), Gaps = 75/432 (17%)
Query: 50 QVEALKLLY-SGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSST----FLLIYPTRALIN 104
Q EA +Y S +N ++S+PT SGK+ +F L I E +S T + I PT++L
Sbjct: 2 QSEAFPSIYESNENCIISSPTGSGKTVLFELAILRLIKETNSDTNNTKIIYIAPTKSLC- 60
Query: 105 NQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPR 164
+E F VG +LT D E + + K N+I TTP+ L R
Sbjct: 61 -----YEMYKNWFPSFVNLSVG--MLTSDTSFLETEKAK--KCNIIITTPEKWDL-LTRR 110
Query: 165 WLDYKWLFKNLKLLVVDELHIYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNP 224
W DY LF+ +KL++VDE+H + G+++ + R+ + N R +ALSAT+ N
Sbjct: 111 WSDYSRLFELVKLVLVDEIHTIKEKRGASLEVI----LTRMNTMCQNIRFVALSATVPNI 166
Query: 225 KD-----------------FAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIRQ 267
+D F E + + + + + K F+ +LI +
Sbjct: 167 EDLALWLKTNNELPANILSFDESYRQVQLTKFVYGYSFNCKN---DFQKDAIYNSKLI-E 222
Query: 268 IVERLVENDVKTLVFFDSRKGTERIMRMFLGSKVFNL---------------------IT 306
I+E+ +N L+F +R T + L + +F+ I
Sbjct: 223 IIEKHADNR-PVLIFCPTRASTISTAKFLLNNHIFSKSKKRCNHNPSDKILNECMQQGIA 281
Query: 307 TYKGTLTKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVI-------NYGIPSDG 359
+ ++ +R +E +F G + L +T+ L +G+++ +I + I
Sbjct: 282 FHHAGISLEDRTAVEKEFLAGSINILCSTSTLAVGVNLPAYLVIIKGTKSWNSSEIQEYS 341
Query: 360 LFSLIQRFGRAGRDPNRVAINGIVLRRNGLDYYYKEHFEELVEGIEKGLVEGIPVNLDNE 419
++Q GRAGR +++ D K+ +E L+ G + L + +NL
Sbjct: 342 DLDVLQMIGRAGRPQFETHGCAVIM----TDSKMKQTYENLIHGTDV-LESSLHLNLIEH 396
Query: 420 RIAKKHLHYLLS 431
A+ L + S
Sbjct: 397 LAAETSLETVYS 408
>pir||S61610 HFM1 protein - yeast (Saccharomyces cerevisiae)
>gi|1150588|emb|CAA64136.1| (X94357) ORF NRE1041;
EMBL:SC22156;U22156 [Saccharomyces cerevisiae]
>gi|1322927|emb|CAA96971.1| (Z72773) ORF YGL251c
[Saccharomyces cerevisiae]
Length = 1046
Score = 86.6 bits (211), Expect = 1e-15
Identities = 103/432 (23%), Positives = 180/432 (40%), Gaps = 75/432 (17%)
Query: 50 QVEALKLLY-SGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSST----FLLIYPTRALIN 104
Q EA +Y S +N ++S+PT SGK+ +F L I E +S T + I PT++L
Sbjct: 2 QSEAFPSIYESNENCIISSPTGSGKTVLFELAILRLIKETNSDTNNTKIIYIAPTKSLC- 60
Query: 105 NQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPR 164
+E F VG +LT D E + + K N+I TTP+ L R
Sbjct: 61 -----YEMYKNWFPSFVNLSVG--MLTSDTSFLETEKAK--KCNIIITTPEKWDL-LTRR 110
Query: 165 WLDYKWLFKNLKLLVVDELHIYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNP 224
W DY LF+ +KL++VDE+H + G+++ + R+ + N R +ALSAT+ N
Sbjct: 111 WSDYSRLFELVKLVLVDEIHTIKEKRGASLEVI----LTRMNTMCQNIRFVALSATVPNI 166
Query: 225 KD-----------------FAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIRQ 267
+D F E + + + + + K F+ +LI +
Sbjct: 167 EDLALWLKTNNELPANILSFDESYRQVQLTKFVYGYSFNCKN---DFQKDAIYNSKLI-E 222
Query: 268 IVERLVENDVKTLVFFDSRKGTERIMRMFLGSKVFNL---------------------IT 306
I+E+ +N L+F +R T + L + +F+ I
Sbjct: 223 IIEKHADNR-PVLIFCPTRASTISTAKFLLNNHIFSKSKKRCNHNPSDKILNECMQQGIA 281
Query: 307 TYKGTLTKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVI-------NYGIPSDG 359
+ ++ +R +E +F G + L +T+ L +G+++ +I + I
Sbjct: 282 FHHAGISLEDRTAVEKEFLAGSINILCSTSTLAVGVNLPAYLVIIKGTKSWNSSEIQEYS 341
Query: 360 LFSLIQRFGRAGRDPNRVAINGIVLRRNGLDYYYKEHFEELVEGIEKGLVEGIPVNLDNE 419
++Q GRAGR +++ D K+ +E L+ G + L + +NL
Sbjct: 342 DLDVLQMIGRAGRPQFETHGCAVIM----TDSKMKQTYENLIHGTDV-LESSLHLNLIEH 396
Query: 420 RIAKKHLHYLLS 431
A+ L + S
Sbjct: 397 LAAETSLETVYS 408
>emb|CAC11964.1| (AL445065) DNA helicase related protein [Thermoplasma acidophilum]
Length = 674
Score = 79.6 bits (193), Expect = 1e-13
Identities = 105/374 (28%), Positives = 163/374 (43%), Gaps = 77/374 (20%)
Query: 44 FKLYSHQVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFLLIYPTRALI 103
F+LY HQ A++ + G+NVVVS PTA+GK+ I I++ F + S + I P R+L
Sbjct: 21 FQLYDHQRMAIEQIRKGRNVVVSVPTAAGKTLIAYSAIYETFQRNLKSIY--IVPLRSLA 78
Query: 104 NNQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTT---PDMLHYN 160
+ + R ++ G KV SI GD + S R + VI T+ +LH++
Sbjct: 79 MEKFSELSRLRDL-----GLKVKMSI--GDYDDSPDFIKRYDA--VILTSEKADSLLHHD 129
Query: 161 LLPRWLDYKWLFKNLKLLVVDELHIY----RGVFGSNVAYVFRRLFLRLRRLKVNP--RI 214
++ ++ LLV+DE+H RG VA + R VNP RI
Sbjct: 130 --------PYILNDVGLLVLDEIHTIGDESRGPTLETVASIAR---------YVNPDVRI 172
Query: 215 LALSATLKNPKDFAEKFFGFEFEEVTEAGNPSPKRYIIMF------EPTRFSGEQLIRQI 268
LALSAT+ N + A + + P P + I++ + R SG I QI
Sbjct: 173 LALSATVSNAMELAS---WLDASLIKSDFRPVPLKTGILYRDQLYLDGKRRSGVS-INQI 228
Query: 269 VERLVENDVKTLVFFDSRK---GTERIMRMFLGSKVFNLITT------------------ 307
+ VE++ + L+F SRK T R + GS I++
Sbjct: 229 IRETVEDNGQVLMFVSSRKKAEDTARDLAQIFGSDANIKISSDETNVYDDMLNEILPRGV 288
Query: 308 --YKGTLTKLERWRIESDFREGKLKALLTTNALELGID-------VGDLDAVINYGIPSD 358
+ L+ +R IE +FR ++K ++ T L G++ V D+ + GI
Sbjct: 289 AFHHAGLSNDQRAFIEREFRARRIKVIVATPTLAAGVNLPARLVIVRDITRWGSDGISYL 348
Query: 359 GLFSLIQRFGRAGR 372
+ Q GRAGR
Sbjct: 349 TNMEIKQMIGRAGR 362
>dbj|BAB05326.1| (AP001512) ATP-dependent DNA helicase [Bacillus halodurans]
Length = 491
Score = 77.6 bits (188), Expect = 5e-13
Identities = 94/339 (27%), Positives = 154/339 (44%), Gaps = 47/339 (13%)
Query: 48 SHQVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFLLIYPTRALINNQL 107
S Q E ++ L G +V PT +GKS ++L + L+I P +L+ +Q+
Sbjct: 18 SGQKEVIEALVEGNDVFAMLPTGTGKSICYQLPA-----RITEGVTLVISPLLSLMEDQV 72
Query: 108 EKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKP--NVIFTTPDMLHYNLLPRW 165
++ K G K + L+ + + RI ++ ++F +P+M+ + ++
Sbjct: 73 QQL--------KSNGWK-DVAALSSFLSKGAKERIIKQLHLYKLLFLSPEMVQHPVV--- 120
Query: 166 LDYKWLFKNLKLL-----VVDELHIYRGVFGSNVAYVFRRLFLRLRRLKV---NPRILAL 217
FK LK + VVDE H S + FR FLRL +K NP LAL
Sbjct: 121 ------FKRLKQVKVSYFVVDEAHCI-----SQWGHDFRPDFLRLSDVKHQLGNPPCLAL 169
Query: 218 SATLKNPKDFAEKFFGFEFEE-VTEAGNPSPKRYIIMFE--PTRFSGEQLIRQIVERLVE 274
+AT P + +E VT + I E PT ++IR I+ER
Sbjct: 170 TATA-TPAVQQDILTQLSIDEAVTIVHSVDRPNISISVEQTPTVKDKLEVIRGIIER--- 225
Query: 275 NDVKTLVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFREGKLKALLT 334
+ +++F SR +E+I R + V + Y G ++ +R I+ F G+L + +
Sbjct: 226 HSGAGIIYFSSRLWSEQIARELM-LNVKKRVAFYHGGMSNEDRILIQQQFMAGELDLICS 284
Query: 335 TNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRD 373
T+A +GI+ D+ VI+Y P + S +Q GRAGRD
Sbjct: 285 TSAFGMGINKQDIRFVIHYHYPQQ-IASYVQEIGRAGRD 322
>gi|7305019 eukaryotic translation initiation factor 4A2 [Mus musculus]
>gi|50823|emb|CAA31025.1| (X12507) initiation factor
4AII (AA 1 - 407) [Mus musculus]
Length = 407
Score = 77.3 bits (187), Expect = 7e-13
Identities = 92/373 (24%), Positives = 168/373 (44%), Gaps = 55/373 (14%)
Query: 50 QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEF-LEDSSSTFLLIYPTRALINNQLE 108
Q A+ G +V+ + +GK+ F + I + +E + L++ PTR L Q++
Sbjct: 60 QQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQ-QIQ 118
Query: 109 KFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDY 168
K + T ++ + G +E ++++ E P+++ TP + L R+L
Sbjct: 119 KVILALGDYMGATC----HACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSP 174
Query: 169 KWLFKNLKLLVVDELH--IYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKD 226
KW+ K+ V+DE + RG +++ R+++L + +++ LSAT+ P D
Sbjct: 175 KWI----KMFVLDEADEMLSRGFKD--------QIYERVQKLNTSIQVVLLSATM--PTD 220
Query: 227 FAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIRQIVER----------LVEND 276
E VT+ P R ++ E G + VER L E
Sbjct: 221 VLE---------VTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETL 271
Query: 277 VKT--LVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFREGKLKALLT 334
T ++F ++R+ + + ++ ++ G + + ER I +FR G + L+T
Sbjct: 272 TITQAVIFLNTRRKVDWLTEKM--QAIYFTVSALHGDMDQKERDVIMREFRSGSSRVLIT 329
Query: 335 TNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNR-VAINGI------VLRRN 387
T+ L GIDV + VINY +P++ + I R GR GR + VAIN + +LR
Sbjct: 330 TDLLARGIDVQQVSLVINYDLPTN-RENYIHRIGRGGRFGRKGVAINFVTEEDKRILRH- 387
Query: 388 GLDYYYKEHFEEL 400
++ +Y EE+
Sbjct: 388 -IETFYNTTVEEM 399
>prf||1413329A gene vasa [Drosophila melanogaster]
Length = 660
Score = 76.1 bits (184), Expect = 2e-12
Identities = 83/345 (24%), Positives = 156/345 (45%), Gaps = 36/345 (10%)
Query: 39 VEELGFKLYSH-QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFL--- 94
V + GFK+ + Q ++ ++ SG++++ T SGK+ F L I + LED L
Sbjct: 260 VNKSGFKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLEDPHELELGRP 319
Query: 95 ---LIYPTRAL---INNQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPN 148
++ PTR L I N+ KF E+ + K+G I+ G + +
Sbjct: 320 QVVIVSPTRELAIQIFNEARKFAFESYL-------KIG--IVYGGTSFRHQNECITRGCH 370
Query: 149 VIFTTPDMLHYNLLPRWLDYKWL-FKNLKLLVVDELHIYRGVFGSNVAYVFRRLFLRLRR 207
V+ TP L ++D ++ F++ + +V+DE + + RR+ +
Sbjct: 371 VVIATPGRLL-----DFVDRTFITFEDTRFVVLDEAD---RMLDMGFSEDMRRIMTHVT- 421
Query: 208 LKVNPRILALSATLKNP-KDFAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIR 266
++ + L SAT + A +F F + G ++E +++
Sbjct: 422 MRPEHQTLMFSATFPEEIQRMAGEFLKLRFVAIGIVGGRCSDVKQTIYEVNKYAKRS--- 478
Query: 267 QIVERLVENDVKTLVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFRE 326
+++E L E T+VF ++++G + + FL K F T+ +G + +R + DF+
Sbjct: 479 KLIEILSEQADGTIVFVETKRGAD-FLASFLSEKEFPT-TSIRGDRLQSQREQALRDFKN 536
Query: 327 GKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAG 371
G +K L+ T+ G+D+ ++ VINY +PS + + R GR G
Sbjct: 537 GSMKVLIATSVASRGLDIKNIKHVINYDMPSK-IDDYVHRIGRTG 580
>emb|CAB90153.1| (AL355013) putative atp-dependent RNA helicase [Schizosaccharomyces
pombe]
Length = 465
Score = 75.7 bits (183), Expect = 2e-12
Identities = 93/358 (25%), Positives = 163/358 (44%), Gaps = 35/358 (9%)
Query: 33 EEVNKLVEELGFKLYSH-QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSS 91
+E+ + E+LGFK + Q EA+ ++ + ++V+ T SGK+ F L + E + S
Sbjct: 55 DELCEACEKLGFKTPTPIQQEAIPVVLNKRDVIGLAQTGSGKTAAFALPVIQELWNNPSP 114
Query: 92 TFLLIY-PTRALINNQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVI 150
F ++ PTR L E+FE I I R V ++ G +++ + +KP+V+
Sbjct: 115 FFAVVLAPTRELAYQISEQFEA---IGGSIGVRSV---VIVGGMDMVTQAVALSKKPHVL 168
Query: 151 FTTPDMLHYNLLPRWLDYKWLFKNLKLLVVDELHIYRGV-FGSNVAYVFRRLFLRLRRLK 209
TP L +L + KNLK L++DE + FG + + LK
Sbjct: 169 VCTPGRLMDHLENT---KGFSLKNLKYLIMDEADRLLDMDFGPIIDKI----------LK 215
Query: 210 VNP---RILALSATLKNPKDFAEKFFGFEFEEVTEAGNPSPKRYII---MFEPTRFSGEQ 263
+ P R L SAT+ + + ++ + V + S +I +F P +
Sbjct: 216 IIPHERRTLLFSATMTSKVEKLQRASLHQPVRVAVSSKFSTVDTLIQRYLFFPFKHKDTY 275
Query: 264 LIRQIVERLVENDVKTLVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESD 323
L+ +V L N + ++F + T+R+ + L + F+ I + G L++ R +
Sbjct: 276 LV-YLVNELAGNSI--IIFARTVNDTQRLA-ILLRTLGFSAIPLH-GQLSQSNRLGALNK 330
Query: 324 FREGKLKALLTTNALELGIDVGDLDAVINYGIPSD--GLFSLIQRFGRAGRDPNRVAI 379
F+ G L+ T+ G+D+ +D VINY IP+D + R RAGR +A+
Sbjct: 331 FKSGARSTLVATDVAARGLDIPLVDVVINYDIPTDSKAYIHRVGRTARAGRAGKSIAL 388
>gi|11500032 SKI2-family helicase [Archaeoglobus fulgidus]
Length = 691
Score = 75.3 bits (182), Expect = 3e-12
Identities = 95/380 (25%), Positives = 158/380 (41%), Gaps = 64/380 (16%)
Query: 35 VNKLVEELGFKLYSHQVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFL 94
V L EE +L+ Q EA++ ++SGKN++++ PTA+GK+ + + + E ++ S L
Sbjct: 15 VGILKEEGIEELFPPQAEAVEKVFSGKNLLLAMPTAAGKTLLAEMAMVREAIKGGKS--L 72
Query: 95 LIYPTRALINNQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTP 154
+ P RAL + E F++ +I G ++G I TGD E R ++I TT
Sbjct: 73 YVVPLRALAGEKYESFKKWEKI-----GLRIG--ISTGDY---ESRDEHLGDCDIIVTTS 122
Query: 155 DMLHYNLLPRWLDYKWLFKNLKLLVVDELHIYRGVFGSNVAYVFRRLFLRLRRLKVNPRI 214
+ + R W+ K + LVVDE+H+ + L ++RR+ R+
Sbjct: 123 EKADSLIRNR---ASWI-KAVSCLVVDEIHL---LDSEKRGATLEILVTKMRRMNKALRV 175
Query: 215 LALSATLKNPKDFAEKFFGFEFEEVTEAGNPSPKRYIIMFEPT------RFSGEQLIR-- 266
+ LSAT N + AE + + P P ++ E T FS + ++
Sbjct: 176 IGLSATAPNVTEIAE---WLDADYYVSDWRPVPLVEGVLCEGTLELFDGAFSTSRRVKFE 232
Query: 267 QIVERLVENDVKTLVFFDSRKGTERI----------------------------MRMFLG 298
++VE V + LVF +R+G E+ M L
Sbjct: 233 ELVEECVAENGGVLVFESTRRGAEKTAVKLSAITAKYVENEGLEKAILEENEGEMSRKLA 292
Query: 299 SKVFNLITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSD 358
V + L +R +E FR G +K ++ T L G+++ ++ D
Sbjct: 293 ECVRKGAAFHHAGLLNGQRRVVEDAFRRGNIKVVVATPTLAAGVNLPARRVIVRSLYRFD 352
Query: 359 GLFSLI------QRFGRAGR 372
G I Q GRAGR
Sbjct: 353 GYSKRIKVSEYKQMAGRAGR 372
>pir||S01676 ATP-dependent RNA helicase homolog - fruit fly (Drosophila
melanogaster)
Length = 660
Score = 74.9 bits (181), Expect = 4e-12
Identities = 83/345 (24%), Positives = 155/345 (44%), Gaps = 36/345 (10%)
Query: 39 VEELGFKLYSH-QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFL--- 94
V + GFK+ + Q ++ ++ SG++++ T SGK+ F L I + LED L
Sbjct: 260 VNKSGFKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLEDPHELELGRP 319
Query: 95 ---LIYPTRAL---INNQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPN 148
++ PTR L I N+ KF E+ + K+G I+ G + +
Sbjct: 320 QVVIVSPTRELAIQIFNEARKFAFESYL-------KIG--IVYGGTSFRHQNECITRGCH 370
Query: 149 VIFTTPDMLHYNLLPRWLDYKWL-FKNLKLLVVDELHIYRGVFGSNVAYVFRRLFLRLRR 207
V+ TP L ++D ++ F++ + +V+DE + + RR+ +
Sbjct: 371 VVIATPGRLL-----DFVDRTFITFEDTRFVVLDEAD---RMLDMGFSEDMRRIMTHVT- 421
Query: 208 LKVNPRILALSATLKNP-KDFAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIR 266
++ + L SAT + A +F F + G ++E +++
Sbjct: 422 MRPEHQTLMFSATFPEEIQRMAGEFLKLRFVAIGIVGGRCSDVKQTIYEVNKYAKRS--- 478
Query: 267 QIVERLVENDVKTLVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFRE 326
+++E L E T+VF ++++G + + FL K F T+ G + +R + DF+
Sbjct: 479 KLIEILSEQADGTIVFVETKRGAD-FLASFLSEKEFPT-TSIHGDRLQSQREQALRDFKN 536
Query: 327 GKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAG 371
G +K L+ T+ G+D+ ++ VINY +PS + + R GR G
Sbjct: 537 GSMKVLIATSVASRGLDIKNIKHVINYDMPSK-IDDYVHRIGRTG 580
>gi|10957431 RNA helicase, putative [Deinococcus radiodurans]
>gi|7473663|pir||B75633 probable RNA helicase -
Deinococcus radiodurans (strain R1)
>gi|6460860|gb|AAF12564.1|AE001826_33 (AE001826) RNA
helicase, putative [Deinococcus radiodurans]
Length = 1706
Score = 74.9 bits (181), Expect = 4e-12
Identities = 61/191 (31%), Positives = 97/191 (49%), Gaps = 15/191 (7%)
Query: 46 LYSHQVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSST---FLLIYPTRAL 102
L++HQ +A +L G++ VV+T T SGKS + L I D L S +++YP AL
Sbjct: 88 LHAHQRDAARLAREGRSYVVTTGTGSGKSLTYILPIVDHVLRRGSGKGIQAIVVYPMNAL 147
Query: 103 INNQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLL 162
N+Q+E+ + +T R+ TG + E+ I P+++ T ML L
Sbjct: 148 ANSQVEELSKFLGDNGPVTFRRY-----TGQEKREEKDAIIANPPDILLTNYMMLELILT 202
Query: 163 PRWLDYKWLFK---NLKLLVVDELHIYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSA 219
+ D L + ++ +V DELH YRG G++VA + RRL RLR + + SA
Sbjct: 203 RQ--DEAALVRAAEGVRFVVFDELHTYRGRQGADVALLIRRLRERLR--APDAICVGTSA 258
Query: 220 TLKNPKDFAEK 230
T+ + +AE+
Sbjct: 259 TMSSSPVYAER 269
>pir||T50496 hypothetical protein T22D6.50 - Arabidopsis thaliana
>gi|8346548|emb|CAB93712.1| (AL357612) putative protein
[Arabidopsis thaliana]
Length = 1058
Score = 74.9 bits (181), Expect = 4e-12
Identities = 44/139 (31%), Positives = 74/139 (52%), Gaps = 6/139 (4%)
Query: 7 GLESEIVNLHEIPPRKGSYGSFKFRHEEVNK-LVEELGFK-LYSHQVEALKLLYSGKNVV 64
G + ++V++ I RK +Y + E K ++ +G LYSHQ EA+ +GKNV
Sbjct: 353 GSKGQVVHVEVIKARKSAYVEMSDKLSETTKSALKRIGLNTLYSHQAEAISAALAGKNVA 412
Query: 65 VSTPTASGKSEIFRLFIFDEFLEDSSSTFLLIYPTRALINNQLEKFERENEIFSKITGRK 124
V+T T+SGKS + + +F+E +D++S L ++PT+AL +QL + F
Sbjct: 413 VATMTSSGKSLCYNVPVFEELCKDTNSCALYLFPTKALAQDQLRALSDLIKGFE----AS 468
Query: 125 VGNSILTGDVELSERRRIR 143
+ + GD +R R+R
Sbjct: 469 INMGVYDGDTPYKDRTRLR 487
Score = 73.7 bits (178), Expect = 8e-12
Identities = 76/296 (25%), Positives = 141/296 (46%), Gaps = 33/296 (11%)
Query: 265 IRQIVERLVENDVKTLVFFDSRKGTERIM---RMFLGSKVFNL---ITTYKGTLTKLERW 318
+ + +V++ ++ + F SRK E ++ R L +L IT+Y+G +R
Sbjct: 560 VSHLFAEMVQHGLRCIAFCPSRKLCELVLCLTREILAETAPHLVEAITSYRGGYIAEDRR 619
Query: 319 RIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNRVA 378
+IESD GKL + TNALELGIDVG +D ++ G P + SL Q+ GR+GR + +
Sbjct: 620 KIESDLFGGKLCGIAATNALELGIDVGHIDVTLHLGFPG-SIASLWQQAGRSGR-RQKPS 677
Query: 379 INGIVLRRNGLDYYYKEHFEELVEGIEKGLVEGIPVNLDNERIAKKHLHYLLSELGVVDV 438
+ V LD YY ++L G P+ + I ++ H L+ L +
Sbjct: 678 LAVYVAFLGPLDQYYMSFPDKLF---------GSPIECCH--IDSQNKHVLMQHLACAAL 726
Query: 439 NEIPEHWRIALRPLKEEGIVEEYLNPLTNKV-EIRIKKPAIYSSIRSTSDESF-FLVKDE 496
EH PL + + + + L++ + E+R K + R +S + ++ +++
Sbjct: 727 ----EH------PLSLQYDQQHFGSGLSDPLAELRNKGFLSFDPSRDSSSRIWNYIGREK 776
Query: 497 GWIRSSLVRKSGGELLRFVNYLKARGFIIEEVDEVEFYRSLLPGMVYPSRGRLFMV 552
R +R E +R+ K +++E++E + + + G +Y ++GR ++V
Sbjct: 777 NPARIVSIRAI--ETVRYRVMEKKSKDVLDEIEESKAFFHVYEGAIYMNQGRNYLV 830
>gb|AAG22819.1|AF302423_1 (AF302423) RNA helicase II/Gu [Xenopus laevis]
Length = 759
Score = 74.9 bits (181), Expect = 4e-12
Identities = 92/378 (24%), Positives = 167/378 (43%), Gaps = 35/378 (9%)
Query: 9 ESEIVNLHEIPPRKGSYGSFKFRHEEVNKLVEELGFKLYSHQVEALKLLYSGKNVVVSTP 68
E + +N +I G + F E + L + L+ Q + YSGK+VVV
Sbjct: 168 EEQDINQEKID---GDFSKFPLSKETIKNLQAKGVSYLFPIQSKTFHTAYSGKDVVVQAR 224
Query: 69 TASGKSEIFRLFIFDEFLEDS-------SSTFLLIYPTRALINNQLEKFERENEIFSKIT 121
T +GK+ F + + ++ ED + +++ PTR L + NEI S IT
Sbjct: 225 TGTGKTFSFAIPLVEKLNEDQQPLARGRAPRVIILTPTRELA------IQITNEIRS-IT 277
Query: 122 GRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDYKWLFKNLKLLVVD 181
+K+ S G ++ ++ + + TP + +L+ +Y+ LK +V+D
Sbjct: 278 -KKLKVSCFYGGTPYQQQVFAIKDGIDFLVGTPGRVR-DLVQ---NYRLDLTTLKHVVLD 332
Query: 182 ELHIYRGV-FGSNVAYVFRRLFLRLRR-LKVNPRILALSATLKN-PKDFAEKFFGFEFEE 238
E+ + + F V + L +R + + NP+ L SAT + + A+K+ +FE+
Sbjct: 333 EVDMMFDMGFSEQVEEI---LSVRYKADPEENPQTLLFSATCPDWMYNMAKKYMRKQFEK 389
Query: 239 VTEAGNPSPKRYI----IMFEPTRFSGEQLIRQIVERLVENDVKTLVFFDSRKGTERIMR 294
+ G+ S K + E TR ++ +V+ + KT++F DS+ +
Sbjct: 390 IDLIGHRSQKAATTVEHLAIECTRSQKAAVLGDLVQVYSGSHGKTIIFCDSKLEAHTLAT 449
Query: 295 MFLGSKVFNLITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYG 354
K + G L + ER + FR+G + L+ TN G+D+ ++D V+ Y
Sbjct: 450 SCGSLK--QSAKSLHGDLQQKEREVVLKGFRQGTFEVLIATNVAARGLDIPEVDLVVLYS 507
Query: 355 IPSDGLFSLIQRFGRAGR 372
P + + + R GR GR
Sbjct: 508 APKEA-DAYVHRSGRTGR 524
>pir||C69187 conserved hypothetical protein MTH656 - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2621738|gb|AAB85161.1| (AE000845) ATP-dependent RNA
helicase related protein [Methanobacterium
thermoautotrophicum]
Length = 837
Score = 74.5 bits (180), Expect = 5e-12
Identities = 91/329 (27%), Positives = 145/329 (43%), Gaps = 31/329 (9%)
Query: 57 LYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFLLIYPTRALINNQLEKFERENEI 116
L G++++V + TASGK+ I L L F+ + P AL N + F R
Sbjct: 235 LLEGEDLMVVSATASGKTLIAELAGIPRAL--GGEKFIYLTPLVALANQKYRDFRRRYSP 292
Query: 117 FSKITGRKVGNSILTGDVELSERRRIRR---EKPNVIFTTPDMLHYNLLPRWLDYKWLFK 173
T KVG S + EL RI K +++ T + + Y L +
Sbjct: 293 LKLKTAIKVGMSRIRARDEL----RIPETDVSKADIVVGTYEGMDYILRA---GRSGILG 345
Query: 174 NLKLLVVDELHIYRGVF-GSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKDFAEKFF 232
++ ++V+DE+H GS + + + R+RRL + +I+ALSAT+KN + A +F
Sbjct: 346 DVGVVVIDEIHTLEDEERGSRL----KGMIKRIRRLFPDAQIIALSATVKNNLEVASEF- 400
Query: 233 GFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIRQIVERLVENDVK------TLVFFDSR 286
G E P P ++F + LI ++ ER + + T+VF +SR
Sbjct: 401 GLRLVEYDR--RPVPLERHLVFSRGEEDKKNLILRLAEREFSTESEKGFRGQTIVFTNSR 458
Query: 287 KGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGIDVGD 346
+ T R++ +L + + G L+ ER RIE F +L A++TT AL G+D
Sbjct: 459 RKT-RLIADYLTRRGVRAAAYHAG-LSYRERQRIERAFASQELAAIVTTAALAAGVDFPA 516
Query: 347 LDAVINYGIPSDGLF---SLIQRFGRAGR 372
V + + Q GRAGR
Sbjct: 517 SQVVFETLLMGNRWLMPNEFAQMLGRAGR 545
>sp|Q09811|HUS2_SCHPO ATP-DEPENDENT DNA HELICASE HUS2 >gi|2130397|pir||S62467
ATP-dependent DNA helicase hus2 - fission yeast
(Schizosaccharomyces pombe) >gi|1019410|emb|CAA91177.1|
(Z54354) atp-dependent dna helicase hus2
[Schizosaccharomyces pombe] >gi|1684754|emb|CAA70577.1|
(Y09426) DNA-helicase [Schizosaccharomyces pombe]
Length = 1328
Score = 74.1 bits (179), Expect = 6e-12
Identities = 92/345 (26%), Positives = 158/345 (45%), Gaps = 40/345 (11%)
Query: 43 GFKLYSHQVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSS--TFLLIYPTR 100
GF+ +Q+EA+ SGK+V + PT GKS ++L +E +S L+I P
Sbjct: 519 GFR--KNQLEAINGTLSGKDVFILMPTGGGKSLCYQL---PAVIEGGASRGVTLVISPLL 573
Query: 101 ALINNQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRI------RREKPNVIFTTP 154
+L+ +QL+ + N + + L+G+ ERR++ + +++ TP
Sbjct: 574 SLMQDQLDHLRKLN----------IPSLPLSGEQPADERRQVISFLMAKNVLVKLLYVTP 623
Query: 155 DMLHYN-LLPRWLDYKWLFKNLKLLVVDELHIYRGVFGSNVAYVFRRLFLRLRRLKVNPR 213
+ L N + R L + K L +V+DE H +G + +++L L R + P
Sbjct: 624 EGLASNGAITRVLKSLYERKLLARIVIDEAHCVSH-WGHDFRPDYKQLGLLRDRYQGIP- 681
Query: 214 ILALSATLKN--PKDFAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIRQIVER 271
+AL+AT KD E+ + N Y I +P + +L R I
Sbjct: 682 FMALTATANEIVKKDIINTLRMENCLELKSSFNRPNLFYEI--KPKKDLYTELYRFISNG 739
Query: 272 LVENDVKTLVFFDSRKGTERI---MRMFLGSKVFNLITTYKGTLTKLERWRIESDFREGK 328
+ +++ SR E++ +R G K ++ Y L K+ER RI+++++ G
Sbjct: 740 HLHES--GIIYCLSRTSCEQVAAKLRNDYGLKAWH----YHAGLEKVERQRIQNEWQSGS 793
Query: 329 LKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRD 373
K ++ T A +G+D GD+ VI++ P L Q GRAGRD
Sbjct: 794 YKIIVATIAFGMGVDKGDVRFVIHHSFPK-SLEGYYQETGRAGRD 837
>pir||H64474 hypothetical protein MJ1401 - Methanococcus jannaschii
>gi|1592049|gb|AAB99409.1| (U67580) putative ATP
dependent RNA helicase [Methanococcus jannaschii]
Length = 808
Score = 74.1 bits (179), Expect = 6e-12
Identities = 105/434 (24%), Positives = 194/434 (44%), Gaps = 54/434 (12%)
Query: 33 EEVNKLVEELGFK-LYSHQVEALKL-LYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSS 90
EE+ ++++ G + L Q ++K L +G ++++ + T+SGK+ I L ++ +
Sbjct: 198 EELKEIIKSRGIEELLPVQTLSVKAGLLNGDDLLIISATSSGKTLIGELAGIKNLIK-TG 256
Query: 91 STFLLIYPTRALINNQLEKF-ERENEIFSKITGR----KVGNSILTGDVELSERRRIRRE 145
FL + P AL N + +F ER ++ K++ R ++G + DVE S
Sbjct: 257 KKFLFLVPLVALANQKYLEFKERYEKLGFKVSLRVGLGRIGKKV---DVETSL------- 306
Query: 146 KPNVIFTTPDMLHYNLLPRWLDYKWLFKNLKLLVVDELHIYRGVFGSNVAYVFRRL---F 202
++I T + + Y + + L K++ +V+DE+H N+ RL
Sbjct: 307 DADIIVGTYEGIDYLIRTKRL------KDIGTVVIDEIH------SLNLEERGARLDGLI 354
Query: 203 LRLRRLKVNPRILALSATLKNPKDFAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGE 262
RLR L + + LSAT+ NPK+ A++ + V G P P I+F F+
Sbjct: 355 GRLRFLFKEAQKIYLSATIGNPKELAKQL---NAKLVLYNGRPVPLERHIIFCKNDFAKL 411
Query: 263 QLIRQIVERLVENDVK------TLVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLE 316
+I++IV+R +N K L+F SRK E + + + Y G + ++
Sbjct: 412 NIIKEIVKREWQNISKFGYRGQCLIFTYSRKRAEYLAKALKSKGI--KAEFYHGGMEYIK 469
Query: 317 RWRIESDFREGKLKALLTTNALELGIDVGDLDAVI-NYGIPSDGL--FSLIQRFGRAGRD 373
R ++E DF K++ ++TT AL G+D ++ + + +D L Q GRAGR
Sbjct: 470 RRKVEDDFANQKIQCVVTTAALSAGVDFPASTVILESLAMGADWLNPAEFQQMCGRAGRK 529
Query: 374 PNRVAINGIVLRRNGLDYYYKEHFEELVEGIEKGLVEGIPVNLDNERIAKKHLHYLLSEL 433
+L G Y+ K E + + L+ +P ++ E + +L+ +
Sbjct: 530 GMHEIGKVYLLVEIGKKYHAK--MENTEDEVAFKLLNAVPEDVKVEYNEDEEEEQILATI 587
Query: 434 GV-----VDVNEIP 442
D++ +P
Sbjct: 588 SAGITNRYDIDRVP 601
>pir||G71051 probable ATP-dependent helicase LHR - Pyrococcus horikoshii
>gi|3257526|dbj|BAA30209.1| (AP000005) 1352aa long
hypothetical ATP-dependent helicase LHR [Pyrococcus
horikoshii]
Length = 1352
Score = 74.1 bits (179), Expect = 6e-12
Identities = 80/312 (25%), Positives = 148/312 (46%), Gaps = 39/312 (12%)
Query: 53 ALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLE-------DSSSTFLLIYPTRAL--- 102
A+ ++ G+NV++S+PT SGK+ L I E + + + I P RAL
Sbjct: 43 AIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRKGKLEDKIYCVYISPLRALNND 102
Query: 103 INNQLEKFERENEIFSKITGRKVGN---SILTGDVELSERRRIRREKPNVIFTTPDMLHY 159
I LE+ RE + ++ G ++ ++ T D E+ ++ ++ P+++ TTP+ L
Sbjct: 103 IRRNLEEPLREIKELAQELGEEIPEIRIAVRTSDTSSYEKSKMVKKPPHILITTPESLAI 162
Query: 160 NL-LPRWLDYKWLFKNLKLLVVDELH-IYRGVFGSNVAYVFRRLFLRLRRLKVNPRILAL 217
L P+ ++ ++++ ++VDE+H + GS++A RL + R V + L
Sbjct: 163 ALNAPK---FRERLRDVRWVIVDEVHALAENKRGSHLALTLERLRELVGRDFVR---IGL 216
Query: 218 SATLKNPKDFAEKFFGFEFE---------EVTEAGNPSPKRYIIMFEPTRFSGEQLIRQI 268
SAT+ ++ A+ FGF + +V+ A K ++ + E L +
Sbjct: 217 SATIHPLEEVAKFVFGFNDDGTPRSGLIVDVSFAKQTEIKVESVVEDLIYTDAETLSNAL 276
Query: 269 VERLVE---NDVKTLVFFDSRKGTERIMRMFLGSKVF----NLITTYKGTLTKLERWRIE 321
RL E TL+F ++R G ER+ F K F LI T+ +L++ R +E
Sbjct: 277 YNRLAELIRKHKTTLIFTNTRSGAERV--AFNLKKRFPEFKGLIETHHSSLSREVRLDVE 334
Query: 322 SDFREGKLKALL 333
+ G+L+A++
Sbjct: 335 EKLKRGELRAVV 346
>gi|11435040 similar to eukaryotic translation initiation factor 4A, isoform 2
(H. sapiens) [Homo sapiens]
>gi|2507330|sp|P10630|IF42_MOUSE EUKARYOTIC INITIATION
FACTOR 4A-II (EIF-4A-II) >gi|90966|pir||S00985
translation initiation factor eIF-4A II - mouse
>gi|673434|emb|CAA40269.1| (X56953) protein synthesis
initiation factor 4A [Mus musculus]
>gi|227239|prf||1617105C initiation factor 4AII
[Oryctolagus cuniculus]
Length = 407
Score = 73.4 bits (177), Expect = 1e-11
Identities = 94/373 (25%), Positives = 169/373 (45%), Gaps = 55/373 (14%)
Query: 50 QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEF-LEDSSSTFLLIYPTRALINNQLE 108
Q A+ G +V+ + +GK+ F + I + +E + L++ PTR L Q++
Sbjct: 60 QQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQ-QIQ 118
Query: 109 KFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDY 168
K + T ++ + G +E ++++ E P+++ TP + L R+L
Sbjct: 119 KVILALGDYMGATC----HACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSP 174
Query: 169 KWLFKNLKLLVVDELH--IYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKD 226
KW+ K+ V+DE + RG F + +F++L + +++ LSAT+ P D
Sbjct: 175 KWI----KMFVLDEADEMLSRG-FKDQIYEIFQKL-------NTSIQVVLLSATM--PTD 220
Query: 227 FAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIRQIVER----------LVEND 276
E VT+ P R ++ E G + VER L E
Sbjct: 221 VLE---------VTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETL 271
Query: 277 VKT--LVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFREGKLKALLT 334
T ++F ++R+ + + + ++ F ++ G + + ER I +FR G + L+T
Sbjct: 272 TITQAVIFLNTRRKVDWLTEK-MHARDFT-VSALHGDMDQKERDVIMREFRSGSSRVLIT 329
Query: 335 TNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNR-VAINGI------VLRRN 387
T+ L GIDV + VINY +P++ + I R GR GR + VAIN + +LR
Sbjct: 330 TDLLARGIDVQQVSLVINYDLPTN-RENYIHRIGRGGRFGRKGVAINFVTEEDKRILR-- 386
Query: 388 GLDYYYKEHFEEL 400
++ +Y EE+
Sbjct: 387 DIETFYNTTVEEM 399
>emb|CAA40268.1| (X56953) protein synthesis initiation factor 4A [Mus musculus]
Length = 408
Score = 73.4 bits (177), Expect = 1e-11
Identities = 94/373 (25%), Positives = 169/373 (45%), Gaps = 55/373 (14%)
Query: 50 QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEF-LEDSSSTFLLIYPTRALINNQLE 108
Q A+ G +V+ + +GK+ F + I + +E + L++ PTR L Q++
Sbjct: 61 QQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQ-QIQ 119
Query: 109 KFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDY 168
K + T ++ + G +E ++++ E P+++ TP + L R+L
Sbjct: 120 KVILALGDYMGATC----HACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSP 175
Query: 169 KWLFKNLKLLVVDELH--IYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKD 226
KW+ K+ V+DE + RG F + +F++L + +++ LSAT+ P D
Sbjct: 176 KWI----KMFVLDEADEMLSRG-FKDQIYEIFQKL-------NTSIQVVLLSATM--PTD 221
Query: 227 FAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIRQIVER----------LVEND 276
E VT+ P R ++ E G + VER L E
Sbjct: 222 VLE---------VTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETL 272
Query: 277 VKT--LVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFREGKLKALLT 334
T ++F ++R+ + + + ++ F ++ G + + ER I +FR G + L+T
Sbjct: 273 TITQAVIFLNTRRKVDWLTEK-MHARDFT-VSALHGDMDQKERDVIMREFRSGSSRVLIT 330
Query: 335 TNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNR-VAINGI------VLRRN 387
T+ L GIDV + VINY +P++ + I R GR GR + VAIN + +LR
Sbjct: 331 TDLLARGIDVQQVSLVINYDLPTN-RENYIHRIGRGGRFGRKGVAINFVTEEDKRILR-- 387
Query: 388 GLDYYYKEHFEEL 400
++ +Y EE+
Sbjct: 388 DIETFYNTTVEEM 400
>emb|CAA73168.1| (Y12591) translation initiation factor eIF4A II [Xenopus laevis]
Length = 413
Score = 73.4 bits (177), Expect = 1e-11
Identities = 84/338 (24%), Positives = 151/338 (43%), Gaps = 45/338 (13%)
Query: 50 QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSST-FLLIYPTRALINNQLE 108
Q A+ G +V+ + +GK+ F + I + D +T L++ PTR L +
Sbjct: 65 QQRAIMPCIKGYDVIAQAQSGTGKTATFAISILQQIELDMKATQALMLAPTRELAQQIQK 124
Query: 109 KFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDY 168
+ +G + + +V+ +++ E P++I TP + L R+L
Sbjct: 125 VVMALGDYMGASCHACIGGTNVRAEVQ-----KLQSEAPHIIVGTPGRVFDMLNRRYLSP 179
Query: 169 KWLFKNLKLLVVDELH--IYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKD 226
K++ K+ V+DE + RG F + +F+++ L +N +++ LSAT+ P D
Sbjct: 180 KYI----KMFVLDEADEMLSRG-FKDQIYDIFQKV------LSMNAQVVLLSATM--PAD 226
Query: 227 FAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIRQIVER----------LVEND 276
E VT+ P R ++ E G + VER L E
Sbjct: 227 VLE---------VTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETL 277
Query: 277 VKT--LVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFREGKLKALLT 334
T ++F ++R+ + + + ++ F ++ G + + ER I +FR G + L+T
Sbjct: 278 TITQAVIFINTRRKVDWLTEK-MHARDFT-VSALHGDMDQKERDVIMREFRSGSSRVLIT 335
Query: 335 TNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGR 372
T+ L GIDV + VINY +P++ + I R GR GR
Sbjct: 336 TDLLARGIDVQQVSLVINYDLPTN-RENYIHRIGRGGR 372
>pir||A31922 ATP-dependent RNA helicase homolog - fruit fly (Drosophila
melanogaster) >gi|158796|gb|AAA29013.1| (M23560) Mab4611
antigen (vasa) [Drosophila melanogaster]
Length = 648
Score = 73.0 bits (176), Expect = 1e-11
Identities = 84/350 (24%), Positives = 158/350 (45%), Gaps = 37/350 (10%)
Query: 39 VEELGFKLYSH-QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFL--- 94
V + G+K+ + Q ++ ++ SG++++ T SGK+ F L I + LED L
Sbjct: 247 VNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLEDPHELELGRP 306
Query: 95 ---LIYPTRAL---INNQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPN 148
++ PTR L I N+ KF E+ + K+G I+ G + +
Sbjct: 307 QVCIVSPTRELAIQIFNEARKFAFESYL-------KIG--IVYGGTSFRHQNECITRGCH 357
Query: 149 VIFTTPDMLHYNLLPRWLDYKWL-FKNLKLLVVDELHIYRGVFGSNVAYVFRRLFLRLRR 207
V+ TP L ++D ++ F++ + +V+DE + + RR+ +
Sbjct: 358 VVIATPGRLL-----DFVDRTFITFEDTRFVVLDEAD---RMLDMGFSEDMRRIMTHVT- 408
Query: 208 LKVNPRILALSATLKNP-KDFAEKFF-GFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLI 265
++ + L SAT + A +F + F + G ++E +++
Sbjct: 409 MRPEHQTLMFSATFPEEIQRMAGEFLKNYVFVAIGIVGGACSDVKQTIYEVNKYAKRS-- 466
Query: 266 RQIVERLVENDVKTLVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFR 325
+++E L E T+VF ++++G + + FL K F T+ G + +R + DF+
Sbjct: 467 -KLIEILSEQADGTIVFVETKRGAD-FLASFLSEKEFPT-TSIHGDRLQSQREQALRDFK 523
Query: 326 EGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPN 375
G +K L+ T+ G+D+ ++ VINY +PS + + R GR GR N
Sbjct: 524 NGSMKVLIATSVASRGLDIKNIKHVINYDMPSK-IDDYVHRIGRTGRVGN 572
>gb|AAF44917.1|AE003406_122 (AE003416) symbol=vas; synonym=BG:DS00929.14; cDNA=method:''sim4'',
score:''1000.0'', desc:''LD06084 LD Drosophila
melanogaster embryo BlueScript Drosophila melanogaster
cDNA clone LD06084 5prime, mRNA sequence:AA246989'';
match=method:''sim4'', score:>
>gi|7298204|gb|AAF53438.1| (AE003646) vas gene product
[Drosophila melanogaster]
Length = 661
Score = 73.0 bits (176), Expect = 1e-11
Identities = 84/350 (24%), Positives = 158/350 (45%), Gaps = 37/350 (10%)
Query: 39 VEELGFKLYSH-QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFL--- 94
V + G+K+ + Q ++ ++ SG++++ T SGK+ F L I + LED L
Sbjct: 260 VNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLEDPHELELGRP 319
Query: 95 ---LIYPTRAL---INNQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPN 148
++ PTR L I N+ KF E+ + K+G I+ G + +
Sbjct: 320 QVVIVSPTRELAIQIFNEARKFAFESYL-------KIG--IVYGGTSFRHQNECITRGCH 370
Query: 149 VIFTTPDMLHYNLLPRWLDYKWL-FKNLKLLVVDELHIYRGVFGSNVAYVFRRLFLRLRR 207
V+ TP L ++D ++ F++ + +V+DE + + RR+ +
Sbjct: 371 VVIATPGRLL-----DFVDRTFITFEDTRFVVLDEAD---RMLDMGFSEDMRRIMTHVT- 421
Query: 208 LKVNPRILALSATLKNP-KDFAEKFF-GFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLI 265
++ + L SAT + A +F + F + G ++E +++
Sbjct: 422 MRPEHQTLMFSATFPEEIQRMAGEFLKNYVFVAIGIVGGACSDVKQTIYEVNKYAKRS-- 479
Query: 266 RQIVERLVENDVKTLVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFR 325
+++E L E T+VF ++++G + + FL K F T+ G + +R + DF+
Sbjct: 480 -KLIEILSEQADGTIVFVETKRGAD-FLASFLSEKEFPT-TSIHGDRLQSQREQALRDFK 536
Query: 326 EGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPN 375
G +K L+ T+ G+D+ ++ VINY +PS + + R GR GR N
Sbjct: 537 NGSMKVLIATSVASRGLDIKNIKHVINYDMPSK-IDDYVHRIGRTGRVGN 585
>emb|CAA26842.1| (X03039) put. eIF-4A (aa 1-390) [Mus musculus]
>gi|50819|emb|CAA26845.1| (X03040) put. eIF-4A (aa
1-390) [Mus musculus]
Length = 390
Score = 72.2 bits (174), Expect = 2e-11
Identities = 91/371 (24%), Positives = 162/371 (43%), Gaps = 51/371 (13%)
Query: 50 QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSST-FLLIYPTRALINNQLE 108
Q A+ G +V+ + +GK+ F + I + D +T L++ PTR L +
Sbjct: 43 QQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQK 102
Query: 109 KFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDY 168
+ +G + + +V+ +++ E P++I TP + L R+L
Sbjct: 103 VVMALGDYMGASCHACIGGTNVRAEVQ-----KLQMEAPHIIVGTPGRVFDMLNRRYLSP 157
Query: 169 KWLFKNLKLLVVDELH--IYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKD 226
K++ K+ V+DE + RG F + +F++L N +++ LSAT+ P D
Sbjct: 158 KYI----KMFVLDEADEMLSRG-FKDQIYDIFQKL-------NSNTQVVLLSATM--PSD 203
Query: 227 FAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIRQIVER----------LVEND 276
E VT+ P R ++ E G + VER L E
Sbjct: 204 VLE---------VTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETL 254
Query: 277 VKT--LVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFREGKLKALLT 334
T ++F ++R+ + + + ++ F ++ G + + ER I +FR G + L+T
Sbjct: 255 TITQAVIFINTRRKVDWLTEK-MHARDFT-VSAMHGDMDQKERDVIMREFRSGSSRVLIT 312
Query: 335 TNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNR-VAINGIV----LRRNGL 389
T+ L GIDV + VINY +P++ + I R GR GR + VAIN + +
Sbjct: 313 TDLLARGIDVQQVSLVINYDLPTN-RENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI 371
Query: 390 DYYYKEHFEEL 400
+ +Y EE+
Sbjct: 372 ETFYNTSIEEM 382
>emb|CAA26843.1| (X03039) put. altern. eIF-4A (aa 1-370) [Mus musculus]
>gi|50820|emb|CAA26846.1| (X03040) put. altern. eIF-4A
(aa 1-370) [Mus musculus]
Length = 370
Score = 72.2 bits (174), Expect = 2e-11
Identities = 91/371 (24%), Positives = 162/371 (43%), Gaps = 51/371 (13%)
Query: 50 QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSST-FLLIYPTRALINNQLE 108
Q A+ G +V+ + +GK+ F + I + D +T L++ PTR L +
Sbjct: 23 QQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQK 82
Query: 109 KFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDY 168
+ +G + + +V+ +++ E P++I TP + L R+L
Sbjct: 83 VVMALGDYMGASCHACIGGTNVRAEVQ-----KLQMEAPHIIVGTPGRVFDMLNRRYLSP 137
Query: 169 KWLFKNLKLLVVDELH--IYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKD 226
K++ K+ V+DE + RG F + +F++L N +++ LSAT+ P D
Sbjct: 138 KYI----KMFVLDEADEMLSRG-FKDQIYDIFQKL-------NSNTQVVLLSATM--PSD 183
Query: 227 FAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIRQIVER----------LVEND 276
E VT+ P R ++ E G + VER L E
Sbjct: 184 VLE---------VTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETL 234
Query: 277 VKT--LVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFREGKLKALLT 334
T ++F ++R+ + + + ++ F ++ G + + ER I +FR G + L+T
Sbjct: 235 TITQAVIFINTRRKVDWLTEK-MHARDFT-VSAMHGDMDQKERDVIMREFRSGSSRVLIT 292
Query: 335 TNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNR-VAINGIV----LRRNGL 389
T+ L GIDV + VINY +P++ + I R GR GR + VAIN + +
Sbjct: 293 TDLLARGIDVQQVSLVINYDLPTN-RENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI 351
Query: 390 DYYYKEHFEEL 400
+ +Y EE+
Sbjct: 352 ETFYNTSIEEM 362
>pir||S00986 translation initiation factor eIF-4A I - mouse
Length = 407
Score = 72.2 bits (174), Expect = 2e-11
Identities = 90/371 (24%), Positives = 162/371 (43%), Gaps = 51/371 (13%)
Query: 50 QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSST-FLLIYPTRALINNQLE 108
Q A+ G +V+ + +GK+ F + I + D +T L++ PTR L +
Sbjct: 60 QQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQK 119
Query: 109 KFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDY 168
+ +G + + +V+ +++ E P+++ TP + L R+L
Sbjct: 120 VVMALGDYMGASCHACIGGTNVRAEVQ-----KLQMEAPHIVIGTPGRVFDMLNRRYLSP 174
Query: 169 KWLFKNLKLLVVDELH--IYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKD 226
K++ K+ V+DE + RG F + +F++L N +++ LSAT+ P D
Sbjct: 175 KYI----KMFVLDEADEMLSRG-FKDQIYDIFQKL-------NSNTQVVLLSATM--PSD 220
Query: 227 FAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIRQIVER----------LVEND 276
E VT+ P R ++ E G + VER L E
Sbjct: 221 VLE---------VTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETL 271
Query: 277 VKT--LVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFREGKLKALLT 334
T ++F ++R+ + + + ++ F ++ G + + ER I +FR G + L+T
Sbjct: 272 TITQAVIFINTRRKVDWLTEK-MHARDFT-VSAMHGDMDQKERDVIMREFRSGSSRVLIT 329
Query: 335 TNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNR-VAINGIV----LRRNGL 389
T+ L GIDV + VINY +P++ + I R GR GR + VAIN + +
Sbjct: 330 TDLLARGIDVQQVSLVINYDLPTN-RENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI 388
Query: 390 DYYYKEHFEEL 400
+ +Y EE+
Sbjct: 389 ETFYNTSIEEM 399
>gi|4503529 eukaryotic translation initiation factor 4A, isoform 1 [Homo
sapiens] >gi|417180|sp|P04765|IF41_HUMAN EUKARYOTIC
INITIATION FACTOR 4A-I (EIF-4A-I) >gi|422959|pir||S33681
translation initiation factor eIF-4A.I - human
>gi|7428973|pir||FIMS4A translation initiation factor
eIF-4A I - mouse >gi|219403|dbj|BAA02897.1| (D13748)
eukaryotic initiation factor 4AI [Homo sapiens]
>gi|2943740|dbj|BAA25075.1| (AB011595) eIF4A [Mus
musculus] >gi|227238|prf||1617105B initiation factor 4AI
[Oryctolagus cuniculus]
Length = 406
Score = 72.2 bits (174), Expect = 2e-11
Identities = 91/371 (24%), Positives = 162/371 (43%), Gaps = 51/371 (13%)
Query: 50 QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSST-FLLIYPTRALINNQLE 108
Q A+ G +V+ + +GK+ F + I + D +T L++ PTR L +
Sbjct: 59 QQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQK 118
Query: 109 KFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDY 168
+ +G + + +V+ +++ E P++I TP + L R+L
Sbjct: 119 VVMALGDYMGASCHACIGGTNVRAEVQ-----KLQMEAPHIIVGTPGRVFDMLNRRYLSP 173
Query: 169 KWLFKNLKLLVVDELH--IYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKD 226
K++ K+ V+DE + RG F + +F++L N +++ LSAT+ P D
Sbjct: 174 KYI----KMFVLDEADEMLSRG-FKDQIYDIFQKL-------NSNTQVVLLSATM--PSD 219
Query: 227 FAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIRQIVER----------LVEND 276
E VT+ P R ++ E G + VER L E
Sbjct: 220 VLE---------VTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETL 270
Query: 277 VKT--LVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFREGKLKALLT 334
T ++F ++R+ + + + ++ F ++ G + + ER I +FR G + L+T
Sbjct: 271 TITQAVIFINTRRKVDWLTEK-MHARDFT-VSAMHGDMDQKERDVIMREFRSGSSRVLIT 328
Query: 335 TNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNR-VAINGIV----LRRNGL 389
T+ L GIDV + VINY +P++ + I R GR GR + VAIN + +
Sbjct: 329 TDLLARGIDVQQVSLVINYDLPTN-RENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI 387
Query: 390 DYYYKEHFEEL 400
+ +Y EE+
Sbjct: 388 ETFYNTSIEEM 398
>sp|P29562|IF41_RABIT EUKARYOTIC INITIATION FACTOR 4A-I (EIF-4A-I) (EIF4A-I)
Length = 394
Score = 72.2 bits (174), Expect = 2e-11
Identities = 91/371 (24%), Positives = 162/371 (43%), Gaps = 51/371 (13%)
Query: 50 QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSST-FLLIYPTRALINNQLE 108
Q A+ G +V+ + +GK+ F + I + D +T L++ PTR L +
Sbjct: 47 QQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQK 106
Query: 109 KFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDY 168
+ +G + + +V+ +++ E P++I TP + L R+L
Sbjct: 107 VVMALGDYMGASCHACIGGTNVRAEVQ-----KLQMEAPHIIVGTPGRVFDMLNRRYLSP 161
Query: 169 KWLFKNLKLLVVDELH--IYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKD 226
K++ K+ V+DE + RG F + +F++L N +++ LSAT+ P D
Sbjct: 162 KYI----KMFVLDEADEMLSRG-FKDQIYDIFQKL-------NSNTQVVLLSATM--PSD 207
Query: 227 FAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIRQIVER----------LVEND 276
E VT+ P R ++ E G + VER L E
Sbjct: 208 VLE---------VTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETL 258
Query: 277 VKT--LVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFREGKLKALLT 334
T ++F ++R+ + + + ++ F ++ G + + ER I +FR G + L+T
Sbjct: 259 TITQAVIFINTRRKVDWLTEK-MHARDFT-VSAMHGDMDQKERDVIMREFRSGSSRVLIT 316
Query: 335 TNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNR-VAINGIV----LRRNGL 389
T+ L GIDV + VINY +P++ + I R GR GR + VAIN + +
Sbjct: 317 TDLLARGIDVQQVSLVINYDLPTN-RENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI 375
Query: 390 DYYYKEHFEEL 400
+ +Y EE+
Sbjct: 376 ETFYNTSIEEM 386
>pir||S13269 translation initiation factor eIF-4A.I - rabbit (fragment)
Length = 398
Score = 72.2 bits (174), Expect = 2e-11
Identities = 91/371 (24%), Positives = 162/371 (43%), Gaps = 51/371 (13%)
Query: 50 QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSST-FLLIYPTRALINNQLE 108
Q A+ G +V+ + +GK+ F + I + D +T L++ PTR L +
Sbjct: 51 QQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQK 110
Query: 109 KFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDY 168
+ +G + + +V+ +++ E P++I TP + L R+L
Sbjct: 111 VVMALGDYMGASCHACIGGTNVRAEVQ-----KLQMEAPHIIVGTPGRVFDMLNRRYLSP 165
Query: 169 KWLFKNLKLLVVDELH--IYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKD 226
K++ K+ V+DE + RG F + +F++L N +++ LSAT+ P D
Sbjct: 166 KYI----KMFVLDEADEMLSRG-FKDQIYDIFQKL-------NSNTQVVLLSATM--PSD 211
Query: 227 FAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIRQIVER----------LVEND 276
E VT+ P R ++ E G + VER L E
Sbjct: 212 VLE---------VTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETL 262
Query: 277 VKT--LVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFREGKLKALLT 334
T ++F ++R+ + + + ++ F ++ G + + ER I +FR G + L+T
Sbjct: 263 TITQAVIFINTRRKVDWLTEK-MHARDFT-VSAMHGDMDQKERDVIMREFRSGSSRVLIT 320
Query: 335 TNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNR-VAINGIV----LRRNGL 389
T+ L GIDV + VINY +P++ + I R GR GR + VAIN + +
Sbjct: 321 TDLLARGIDVQQVSLVINYDLPTN-RENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI 379
Query: 390 DYYYKEHFEEL 400
+ +Y EE+
Sbjct: 380 ETFYNTSIEEM 390
>pir||JS0039 translation initiation factor eIF-4A - mouse
>gi|556308|gb|AAA50407.1| (L36611) protein synthesis
initiation factor 4A [Mus musculus]
Length = 406
Score = 71.8 bits (173), Expect = 3e-11
Identities = 91/371 (24%), Positives = 162/371 (43%), Gaps = 51/371 (13%)
Query: 50 QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSST-FLLIYPTRALINNQLE 108
Q A+ G +V+ + +GK+ F + I + D +T L++ PTR L +
Sbjct: 59 QQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQK 118
Query: 109 KFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDY 168
+ +G + + +V+ +++ E P++I TP + L R+L
Sbjct: 119 VVMALGDYMGASCHACIGGTNVRAEVQ-----KLQMEAPHIIVGTPGRVFDMLNRRYLSP 173
Query: 169 KWLFKNLKLLVVDELH--IYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKD 226
K++ K+ V+DE + RG F + +F++L N +++ LSAT+ P D
Sbjct: 174 KYI----KMFVLDEADEMLSRG-FKDQIYDIFQKL-------NSNTQVVLLSATM--PSD 219
Query: 227 FAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIRQIVER----------LVEND 276
E VT+ P R ++ E G + VER L E
Sbjct: 220 VLE---------VTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETL 270
Query: 277 VKT--LVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFREGKLKALLT 334
T ++F ++R+ + + + ++ F + + G + + ER I +FR G + L+T
Sbjct: 271 TITQAVIFINTRRKVDWLTEK-MHARDFTVCAMH-GDMDQKERDVIMREFRSGSSRVLIT 328
Query: 335 TNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNR-VAINGIV----LRRNGL 389
T+ L GIDV + VINY +P++ + I R GR GR + VAIN + +
Sbjct: 329 TDLLARGIDVQQVSLVINYDLPTN-RENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI 387
Query: 390 DYYYKEHFEEL 400
+ +Y EE+
Sbjct: 388 ETFYNTSIEEM 398
>gi|4503531 eukaryotic translation initiation factor 4A, isoform 2 [Homo
sapiens] >gi|2500513|sp|Q14240|IF42_HUMAN EUKARYOTIC
INITIATION FACTOR 4A-II (EIF-4A-II) (EIF4A-II)
>gi|485388|dbj|BAA06336.1| (D30655) eukaryotic
initiation factor 4AII [Homo sapiens]
Length = 407
Score = 71.8 bits (173), Expect = 3e-11
Identities = 93/373 (24%), Positives = 165/373 (43%), Gaps = 55/373 (14%)
Query: 50 QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEF-LEDSSSTFLLIYPTRALINNQLE 108
Q A+ G +V+ + +GK+ F + I + +E + L++ PTR L Q++
Sbjct: 60 QQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQ-QIQ 118
Query: 109 KFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDY 168
K + T ++ + G +E ++++ E P+++ TP + L R+L
Sbjct: 119 KVILALGDYMGATC----HACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSP 174
Query: 169 KWLFKNLKLLVVDELH--IYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKNPKD 226
KW+ K+ V+DE + RG F + +F++L N I + A+ P D
Sbjct: 175 KWI----KMFVLDEADEMLSRG-FKDQIYEIFQKL---------NTSIQVVFASATMPTD 220
Query: 227 FAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIRQIVER----------LVEND 276
E VT+ P R ++ E G + VER L E
Sbjct: 221 VLE---------VTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETL 271
Query: 277 VKT--LVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFREGKLKALLT 334
T ++F ++R+ + + + ++ F ++ G + + ER I +FR G + L+T
Sbjct: 272 TITQAVIFLNTRRKVDWLTEK-MHARDFT-VSALHGDMDQKERDVIMREFRSGSSRVLIT 329
Query: 335 TNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNR-VAINGI------VLRRN 387
T+ L GIDV + VINY +P++ + I R GR GR + VAIN + +LR
Sbjct: 330 TDLLARGIDVQQVSLVINYDLPTN-RENYIHRIGRGGRFGRKGVAINFVTEEDKRILR-- 386
Query: 388 GLDYYYKEHFEEL 400
++ +Y EE+
Sbjct: 387 DIETFYNTTVEEM 399
>dbj|BAB02697.1| (AB018114) helicase-like protein [Arabidopsis thaliana]
Length = 1111
Score = 71.8 bits (173), Expect = 3e-11
Identities = 100/382 (26%), Positives = 167/382 (43%), Gaps = 61/382 (15%)
Query: 58 YSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTFLLIYPTRALINNQLEKFERENEIF 117
+S N+++S PT SGK+ +F L I F + S ++ AL K E+ +
Sbjct: 38 HSDINMIISAPTGSGKTVLFELCILRLFSKSISKEGSFLHAKGAL------KTEKLRDWN 91
Query: 118 SKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPD----MLHYNLLPRWLDYKWLFK 173
K + LTGD E + I + ++I TTP+ + Y + L + F
Sbjct: 92 QKFNSWGISCLELTGDNETYSTKNI--QDADIILTTPEKFDAVSRYRVTSGGLGF---FS 146
Query: 174 NLKLLVVDELHIYRGVFGSNVAYVFRRLFL-----RLRRLKV-NPRILALSATLKNPKDF 227
++ L+++DE+H+ G+ + + RL + LR + + R+LA+SAT+ N +D
Sbjct: 147 DIALVLIDEVHLLNDPRGAALEAIVSRLKILSSNHELRSSTLASVRLLAVSATIPNIEDL 206
Query: 228 AE---------KFFGFEFEEVTEAGNPSPKRYI--IMFEPTRFSGEQLIRQIVERLVEND 276
AE K FG E V I +M P S L R+ +ERL E
Sbjct: 207 AEWLKVPTAGIKRFGEEMRPVKLTTKVFGTGLISKVMLLPRMTS--SLKREQLERLRE-- 262
Query: 277 VKTLVFFDSRKGTERIMRMFL---GSKVFNLITTYKGTLTKLERWRIESDFREGKLKALL 333
S +++ M+ ++ +K+ L+ + G L + +R +E F G ++ +
Sbjct: 263 -------ASPMCSDKQMQSYILQGVTKMSQLVGYHNGGLCQKDRSLVEGLFLNGDIQVIC 315
Query: 334 TTNALELGIDVGDLDAVI---NYGIPSDGLF------SLIQRFGRAGRDP-NRVAINGIV 383
TTN L GI++ VI + G + +L+Q GRAGR P + + I+
Sbjct: 316 TTNTLAHGINLPAHTVVIKSTQHFNKEKGHYMEYDRSTLLQMSGRAGRPPFDDTGMVIIM 375
Query: 384 LRRNGLDYYYKEHFEELVEGIE 405
RR + Y E L+ G E
Sbjct: 376 TRRETVHLY-----ENLLNGCE 392
>gb|AAK42080.1| ATP-dependent RNA helicase [Sulfolobus solfataricus]
Length = 343
Score = 71.4 bits (172), Expect = 4e-11
Identities = 82/347 (23%), Positives = 149/347 (42%), Gaps = 35/347 (10%)
Query: 28 FKFRHEEVNKLVEELGF-KLYSHQVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFL 86
F+ E++ K + E G+ K Q + L +GK+V+ T SGK+ + + I +
Sbjct: 2 FENLSEDLRKALSEAGYIKPTKVQEVVIPELLNGKSVIAQAKTGSGKTAAYVIPILER-- 59
Query: 87 EDSSSTFLLIYPTRALINNQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREK 146
+ST L++ PTR L L++ + + +++ S++ G + +R+ R
Sbjct: 60 ---NSTALILSPTRELATQILDEIRKLGKY------KQIDVSLIIGGMSYDGQRQSR--- 107
Query: 147 PNVIFTTPDMLHYNLLPRWLDYKWLFKNLKLLVVDELHIYRGV-FGSNVAYVFRRLFLRL 205
++ TP LL W K F +++VDE + F ++ R+ L
Sbjct: 108 --IVVGTPG----RLLDLWSKGKIDFSGYDVIIVDEADRMLDMGFIDDI-----RMILNH 156
Query: 206 RRLKVNPRILALSATLKNPKDFAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLI 265
K+ SAT+ + K F + E+ + +F R +
Sbjct: 157 SNAKITG---FFSATIPDEIMTLAKEFSKDLREIVLDEYKPVEEVKQIFVKVRNDWSDKV 213
Query: 266 RQIVERLVENDVKTLVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFR 325
+++E + + K LVF +R ++ + G V + G + + R + F+
Sbjct: 214 SKLLEEI--SGEKILVFARTRDRARKLYFLLRGKGVN--VGLLSGDMPQSVRLKNFYGFK 269
Query: 326 EGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGR 372
+GK L+ T+ GID+ D+D VIN+ IP D + + I R GR GR
Sbjct: 270 KGKYNVLVATDLASRGIDIVDVDKVINFDIPRD-VETYIHRVGRTGR 315
>emb|CAA73167.1| (Y12590) translation initiation factor eIF4A I [Xenopus laevis]
Length = 406
Score = 71.4 bits (172), Expect = 4e-11
Identities = 91/350 (26%), Positives = 159/350 (45%), Gaps = 53/350 (15%)
Query: 50 QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSST-FLLIYPTRALINNQLE 108
Q A+ G +V+ + +GK+ F + I + D +T L++ PTR L Q++
Sbjct: 59 QQRAIMPCIKGYDVIAQAQSGTGKTATFAISILQQIELDMKATQALVLAPTRELAQ-QIQ 117
Query: 109 KFERENEIFSKITGRKVG---NSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRW 165
K G +G ++ + G +E ++++ E P+++ TP + L R+
Sbjct: 118 KVVMA-------LGDYMGAGCHACIGGTDVRAEVQKLQSEAPHIVVGTPGRVFDMLNRRY 170
Query: 166 LDYKWLFKNLKLLVVDELH--IYRGVFGSNVAYVFRRLFLRLRRLKVNPRILALSATLKN 223
L K++ K+ V+DE + RG F + +F++L N +++ LSAT+
Sbjct: 171 LSPKYI----KMFVLDEADEMLSRG-FKDQIYDIFQKL-------SSNAQVVLLSATM-- 216
Query: 224 PKDFAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIRQIVER----------LV 273
P D E VT+ P R ++ E G + VER L
Sbjct: 217 PADVLE---------VTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLY 267
Query: 274 ENDVKT--LVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFREGKLKA 331
E T ++F ++R+ + + + ++ F ++ G + + ER I +FR G +
Sbjct: 268 ETLTITQAVIFINTRRKVDWLTEK-MHARDFT-VSALHGDMDQKERDVIMREFRSGSSRV 325
Query: 332 LLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNR-VAIN 380
L+TT+ L GIDV + VINY +P++ + I R GR GR + VAIN
Sbjct: 326 LITTDLLARGIDVQQVSLVINYDLPTN-RENYIHRIGRGGRFGRKGVAIN 374
>gb|AAK42222.1| ATP-dependent RNA helicase [Sulfolobus solfataricus]
Length = 360
Score = 71.0 bits (171), Expect = 5e-11
Identities = 79/347 (22%), Positives = 148/347 (41%), Gaps = 35/347 (10%)
Query: 28 FKFRHEEVNKLVEELGF-KLYSHQVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFL 86
F+ E++ K + E G+ K Q + L +GK+V+V T SGK+ + + I +
Sbjct: 19 FENLSEDLRKALNEAGYIKPTRVQEVVIPELMNGKSVIVQAKTGSGKTAAYVIPILER-- 76
Query: 87 EDSSSTFLLIYPTRALINNQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREK 146
+ST L++ PTR L L++ ++ + +++ S++ G + ++R+ +
Sbjct: 77 ---NSTALILSPTRELATQILDEIKKLGKY------KQIDVSLIIGGMSYDDQRQSK--- 124
Query: 147 PNVIFTTPDMLHYNLLPRWLDYKWLFKNLKLLVVDELHIYRGV-FGSNVAYVFRRLFLRL 205
++ TP LL W K F ++VDE + F ++ + ++
Sbjct: 125 --IVVGTPG----RLLDLWSKGKIDFSGYDFVIVDEADRMLDMGFIDDIRMILNHCNAKI 178
Query: 206 RRLKVNPRILALSATLKNPKDFAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLI 265
SAT+ + K F + E+ + F R +
Sbjct: 179 AGF--------FSATIPDEIMTLAKEFSKDLREIVLDEYKPVEEVKQKFVKVRNDWNDKV 230
Query: 266 RQIVERLVENDVKTLVFFDSRKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFR 325
+++E + N K LVF +R ++ + G V + G + + R + F+
Sbjct: 231 SKLLEEI--NGEKILVFARTRDRARKLYYLLKGKGV--NVGLLSGDMPQSVRLKNFYGFK 286
Query: 326 EGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGR 372
+GK L+ T+ GID+ D++ VIN+ IP D + + I R GR GR
Sbjct: 287 KGKYNVLVATDLASRGIDIIDVNKVINFDIPRD-VETYIHRVGRTGR 332
>sp|P27639|IF4A_CAEEL EUKARYOTIC INITIATION FACTOR 4A (EIF-4A) (EIF4A)
>gi|283547|pir||S26281 translation initiation factor
eIF-4A homolog - Caenorhabditis elegans
>gi|6700|emb|CAA78102.1| (Z12116) unnamed protein
product [Caenorhabditis elegans]
>gi|532818|gb|AAA21170.1| (U13876) C. elegans eukaryotic
initiation factor 4a (EMBL:Z12116) [Caenorhabditis
elegans]
Length = 402
Score = 70.6 bits (170), Expect = 7e-11
Identities = 100/402 (24%), Positives = 174/402 (42%), Gaps = 71/402 (17%)
Query: 33 EEVNKLVEELGFKLYSH-QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEF-LEDSS 90
EE+ + + GF+ S Q A+ +GK+V+ + +GK+ F + I ED
Sbjct: 38 EELLRGIYGFGFEKPSAIQKRAIVPCTTGKDVIAQAQSGTGKTATFSVSILQRIDHEDPH 97
Query: 91 STFLLIYPTRALINNQLEKFERENEIFSKITGRKVGNSILT--GDVELSERRRIRREKPN 148
L++ PTR L Q++K + S + G + +IL G + + +R +
Sbjct: 98 VQALVMAPTRELAQ-QIQK------VMSAL-GEYLNVNILPCIGGTSVRDDQRKLEAGIH 149
Query: 149 VIFTTP----DMLHYNLLPRWLDYKWLFKNLKLLVVDELH--IYRGVFGSNVAYVFRRLF 202
V+ TP DM++ N L +K+ V+DE + RG F + VFR +
Sbjct: 150 VVVGTPGRVGDMINRNALDT--------SRIKMFVLDEADEMLSRG-FKDQIYEVFRSM- 199
Query: 203 LRLRRLKVNPRILALSATLKNPKDFAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGE 262
+ +++ LSAT+ + E +VT +P R ++ + G
Sbjct: 200 ------PQDVQVVLLSATMPS-----------EVLDVTNRFMRNPIRILVKKDELTLEG- 241
Query: 263 QLIRQIVERL---------------VENDVKTLVFFDSRKGTERIMRMFLGSKVFNLITT 307
IRQ + V N + ++F ++R+ + + ++ ++
Sbjct: 242 --IRQFYINVQKDEWKFDCLCDLYNVVNVTQAVIFCNTRRKVDTLTEKMTENQF--TVSC 297
Query: 308 YKGTLTKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRF 367
G + + ER I +FR G + L+TT+ L GIDV + VINY +PS+ + I R
Sbjct: 298 LHGDMDQAERDTIMREFRSGSSRVLITTDILARGIDVQQVSLVINYDLPSN-RENYIHRI 356
Query: 368 GRAGRDPNR-VAINGI----VLRRNGLDYYYKEHFEELVEGI 404
GR+GR + VAIN + + ++ YY EE+ E I
Sbjct: 357 GRSGRFGRKGVAINFVTENDARQLKEIESYYTTQIEEMPESI 398
>gb|AAD34681.1|AC006341_9 (AC006341) Similar to gb|L13612 DEAD-box protein (dbp45A) from
Drosophila melanogaster and is a member of PF|00270
DEAD/DEAH box helicase family. [Arabidopsis thaliana]
Length = 491
Score = 70.6 bits (170), Expect = 7e-11
Identities = 79/336 (23%), Positives = 150/336 (44%), Gaps = 21/336 (6%)
Query: 50 QVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSSTF-LLIYPTRALINNQLE 108
Q + + +G++V+ T SGK+ F L I ED F L++ PTR L E
Sbjct: 85 QTHCVPKILAGRDVLGLAQTGSGKTAAFALPILHRLAEDPYGVFALVVTPTRELAFQLAE 144
Query: 109 KFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNVIFTTPDMLHYNLLPRWLDY 168
+F+ + + S++ G +++ + +P+++ TTP + LL D
Sbjct: 145 QFKALGSCLN------LRCSVIVGGMDMLTQTMSLVSRPHIVITTPGRIKV-LLENNPDV 197
Query: 169 KWLFKNLKLLVVDELHIYRGV-FGSNVAYVFRRLFLRLRRLKVNPRILA-LSATLKNPKD 226
+F K LV+DE V F + +F+ L + L + + + L A L++ +
Sbjct: 198 PPVFSRTKFLVLDEADRVLDVGFQDELRTIFQCLPKSRQTLLFSATMTSNLQALLEHSSN 257
Query: 227 FAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQLIRQIVERLVENDVKT-LVFFDS 285
K + +E E + + +++I + + E + I+ ++ + +++ ++F +
Sbjct: 258 ---KAYFYEAYEGLKTVDTLTQQFIFEDKDAK---ELYLVHILSQMEDKGIRSAMIFVST 311
Query: 286 RKGTERIMRMFLGSKVFNLITTYKGTLTKLERWRIESDFREGKLKALLTTNALELGIDVG 345
+ +R+ M +V N+ ++ R S F+ GK+ LL T+ G+D+
Sbjct: 312 CRTCQRLSLMLDELEVENI--AMHSLNSQSMRLSALSKFKSGKVPILLATDVASRGLDIP 369
Query: 346 DLDAVINYGIPSD--GLFSLIQRFGRAGRDPNRVAI 379
+D VINY IP D + R RAGR V+I
Sbjct: 370 TVDLVINYDIPRDPRDYVHRVGRTARAGRGGLAVSI 405
>pir||T38238 hypothetical protein SPAC23A1.19c - fission yeast
(Schizosaccharomyces pombe) (fragment)
>gi|2879807|emb|CAA16993.1| (AL021813) hypothetical
helicase [Schizosaccharomyces pombe]
Length = 452
Score = 70.2 bits (169), Expect = 9e-11
Identities = 79/298 (26%), Positives = 133/298 (44%), Gaps = 46/298 (15%)
Query: 332 LLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRAGRDPNRVAINGIVLRRNGLDY 391
++ TNALELGID+G LDAVI G P L +L Q+FGRAGR N+ ++ ++ +D
Sbjct: 3 IIATNALELGIDIGSLDAVITIGFPY-SLSNLRQQFGRAGR-RNKSSLAVYIVETFPVDQ 60
Query: 392 YYKEHFEELVEGIEKGLVEGIPVNLDNERIAKKHLHYLLSELGVVDVNEIPEHWRIALRP 451
+Y +H L+ + ++L NE + HL EL +++ + + ++
Sbjct: 61 FYLKH-PILIHTQPNA---ELTLDLTNEVLLASHLQCAAYEL-PINIRSDEKFFGNQIQD 115
Query: 452 LKEEGI--VEEYLNPLTNKVEIRIKKPAIYSSIRSTSDESFFLVKDEGWIRSSLVRKSGG 509
+ E + VEE P + PA IRS S++ F L
Sbjct: 116 ICEANLEMVEESYRPHPKYLPF----PASQVRIRSVSEDMFTL----------------- 154
Query: 510 ELLRFVNYLKARGFIIEEVDEVEFYRSLLPGMVYPSRGRLFMVIDKINVDKFHFVFAQEI 569
V+ + I+E ++ + G VY +G+ F +I +N++K + A ++
Sbjct: 155 -----VDVTNDKNVILELLEPFRVALTAYEGAVYVYQGKTF-IIRLLNINK-RIITAHQV 207
Query: 570 PMNEDVETNVHKSENVEVLKVQD---EKSFGPIKVYFGRLKVTHEYLGY--AVKGKDV 622
DVE + + + +V V+ + G +YFG +K T GY K KD+
Sbjct: 208 ----DVEWSTLQRDFTDVDPVRSLMKKTMHGSTNIYFGAVKATLHVFGYFKVNKQKDI 261
>gb|AAG22818.1|AF302422_1 (AF302422) RNA helicase II/Gu [Xenopus laevis]
Length = 800
Score = 70.2 bits (169), Expect = 9e-11
Identities = 88/367 (23%), Positives = 160/367 (42%), Gaps = 38/367 (10%)
Query: 23 GSYGSFKFRHEEVNKLVEELGFKLYSHQVEALKLLYSGKNVVVSTPTASGKSEIFRLFIF 82
G + F + + + L+ Q + +YSGK+VVV T +GK+ F + +
Sbjct: 221 GDFSKFPISKDTIKNXQAKGVTYLFPIQSKTFHTVYSGKDVVVQARTGTGKTFSFGIPLV 280
Query: 83 DEFLEDS-------SSTFLLIYPTRALINNQLEKFERENEIFSKITGRKVGNSILTGDVE 135
+ ED + +++ PTR L + NE+ S KV + G
Sbjct: 281 ERLSEDQQPLARGRAPRVIILTPTRELA------IQITNELRSMTKKLKV--ACFYGGTP 332
Query: 136 LSERRRIRREKPNVIFTTPDMLHYNLLPRWLDYKWLFKNLKLLVVDELHIYRGV-FGSNV 194
++ ++ + + TP + +L+ +Y+ LK +V+DE+ + V F V
Sbjct: 333 YQQQVFAIKDGIDFLVGTPGRIR-DLVQ---NYRLDLTALKHVVLDEVDMMFDVGFSEQV 388
Query: 195 AYVFRRLFLRLRR-LKVNPRILALSATLKN-PKDFAEKFFGFEFEEVTEAGNPSPKRYI- 251
+ L +R + + NP+ L SAT + + A+K+ ++E+V G+ S K I
Sbjct: 389 EEI---LSVRYKPDPEENPQTLLFSATCPDWMYNVAKKYMRKQYEKVDLVGHRSQKAAIT 445
Query: 252 ---IMFEPTRFSGEQLIRQIVERLVENDVKTLVFFDSRKGTERIMRMFLGSKVFNLITTY 308
+ E R ++ IV+ + KT++F DS+ L + +L +
Sbjct: 446 VEHLAIECNRSQKAAVLGDIVQVYSGSHGKTIIFCDSKLQAHE-----LSTNCGSLKQSA 500
Query: 309 K---GTLTKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQ 365
K G L + ER + FR+G + L+ TN G+D+ ++D V+ Y P + + +
Sbjct: 501 KPLHGDLQQKEREVVLKGFRQGTFEVLIATNVAARGLDIPEVDLVVLYSAPKEA-DAYVH 559
Query: 366 RFGRAGR 372
R GR GR
Sbjct: 560 RSGRTGR 566
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.322 0.142 0.416
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 329607345
Number of Sequences: 2977
Number of extensions: 14742982
Number of successful extensions: 35233
Number of sequences better than 1.0e-10: 71
Number of HSP's better than 0.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 60
Number of HSP's that attempted gapping in prelim test: 35034
Number of HSP's gapped (non-prelim): 106
length of query: 872
length of database: 189,106,746
effective HSP length: 56
effective length of query: 816
effective length of database: 155,591,474
effective search space: 126962642784
effective search space used: 126962642784
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.9 bits)
S2: 169 (70.2 bits)