BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1724 (proS) DE:prolyl-tRNA synthetase (proS)
(480 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||G75072 prolyl-tRNA synthetase (pros) PAB1724 - Pyrococcus a... 993 0.0
pir||A71093 proline--tRNA ligase (EC 6.1.1.15) - Pyrococcus hori... 940 0.0
pir||D72460 probable prolyl-tRNA synthetase APE2328 - Aeropyrum ... 531 e-150
sp|O26708|SYP_METTH PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE... 513 e-144
emb|CAB57731.1| (Y18930) prolyl (glutamyl) tRNA synthetase [Sulf... 501 e-140
gb|AAK40884.1| Prolyl -tRNA synthetase (proS) [Sulfolobus solfat... 501 e-140
emb|CAC12066.1| (AL445066) prolyl-tRNA synthetase related protei... 495 e-139
gi|11499201 prolyl-tRNA synthetase (proS) [Archaeoglobus fulgidu... 481 e-135
sp|Q58635|SYP_METJA PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE... 477 e-133
gb|AAG28517.1|AF197899_1 (AF197899) prolyl-tRNA synthetase [Meth... 455 e-127
emb|CAB71307.1| (AJ130879) prolyl tRNA synthetase [Clostridium s... 355 7e-97
gb|AAG23138.2|AF245446_1 (AF245446) prolyl-tRNA synthetase [Giar... 325 6e-88
dbj|BAB10183.1| (AP000378) prolyl tRNA synthetase [Arabidopsis t... 322 5e-87
emb|CAB36573.1| (AL035472) putative prolyl tRNA synthetase [Myco... 318 1e-85
gb|AAG18956.1| (AE004997) proline-tRNA synthetase; ProS [Halobac... 316 5e-85
pir||D75416 prolyl-tRNA synthetase - Deinococcus radiodurans (st... 315 6e-85
pir||T48004 multifunctional aminoacyl-tRNA ligase-like protein -... 312 7e-84
gi|4758294 glutamyl-prolyl tRNA synthetase; glutamate tRNA ligas... 307 2e-82
gi|11426207 glutamyl-prolyl tRNA synthetase [Homo sapiens] 307 2e-82
pir||T16915 hypothetical protein T20H4.3 - Caenorhabditis elegan... 305 9e-82
pir||A70150 proline--tRNA ligase (EC 6.1.1.15) proS - Lyme disea... 302 6e-81
gi|6321808 Aminoacyl tRNA-synthetase; Yhr020wp [Saccharomyces ce... 291 2e-77
gb|AAF56211.1| (AE003745) Aats-glupro gene product [Drosophila m... 286 3e-76
sp|P28668|SYEP_DROME MULTIFUNCTIONAL AMINOACYL-TRNA SYNTHETASE [... 286 4e-76
pir||T39812 hypothetical protein SPBC19C7.06 - fission yeast (S... 275 6e-73
pir||B82890 prolyl aminoacyl-tRNA synthetase UU452 [imported] - ... 231 1e-59
sp|P75382|SYP_MYCPN PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE... 161 1e-38
sp|P47525|SYP_MYCGE PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE... 150 3e-35
pir||T50797 hypothetical protein T30N20_150 - Arabidopsis thalia... 128 1e-28
sp|O67583|SYT_AQUAE THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI... 106 8e-22
sp|P56881|SYT_THETH THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI... 102 9e-21
pir||B75317 threonyl-tRNA synthetase - Deinococcus radiodurans (... 96 9e-19
gb|AAF68032.1|AF252642_1 (AF252642) glu-prolyl-tRNA aminoacyl sy... 91 2e-17
gb|AAF68027.1|AF252637_1 (AF252637) glu-prolyl-tRNA aminoacyl sy... 91 2e-17
gb|AAF68030.1|AF252640_1 (AF252640) glu-prolyl-tRNA aminoacyl sy... 91 2e-17
gb|AAF68031.1|AF252641_1 (AF252641) glu-prolyl-tRNA aminoacyl sy... 91 2e-17
emb|CAA39134.1| (X55518) ProRS [Escherichia coli] >gi|147362|gb|... 90 7e-17
sp|P16659|SYP_ECOLI PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE... 90 7e-17
pir||YPEC proline--tRNA ligase (EC 6.1.1.15) - Escherichia coli ... 90 7e-17
pir||D82770 threonyl-tRNA synthetase XF0736 [imported] - Xylella... 89 9e-17
pir||S77857 probable proline--tRNA ligase (EC 6.1.1.15) - Mycopl... 89 1e-16
pir||B81939 probable threonine--tRNA ligase (EC 6.1.1.3) NMA0929... 89 1e-16
prf||1614347A Pro-tRNA synthetase [Escherichia coli] 88 3e-16
pir||E81167 threonyl-tRNA synthetase NMB0720 [imported] - Neisse... 87 6e-16
sp|P43830|SYP_HAEIN PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE... 85 2e-15
sp|O51662|SYT_BORBU THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI... 85 2e-15
sp|P18256|SYT2_BACSU THREONYL-TRNA SYNTHETASE 2 (THREONINE--TRNA... 83 5e-15
emb|CAB02510.1| (Z80360) Threonyl tRNA Synthetase [Bacillus subt... 83 5e-15
pir||H82268 prolyl-tRNA synthetase VC0875 [imported] - Vibrio ch... 83 5e-15
emb|CAA23560.1| (V00291) threonyl-tRNA synthetase (thrS; EC 6.1.... 82 1e-14
dbj|BAA15486.1| (D90813) Threonine--tRNA ligase (EC 6.1.1.3) [Es... 82 1e-14
sp|P00955|SYT_ECOLI THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI... 82 1e-14
pdb|1EVK|A Chain A, Crystal Structure Of A Truncated Form Of Thr... 82 1e-14
pir||C81094 prolyl-tRNA synthetase NMB1339 [imported] - Neisseri... 80 4e-14
pir||G81400 proline--tRNA ligase (EC 6.1.1.15) Cj0543 [imported]... 78 2e-13
sp|Q9WZJ9|SYT_THEMA THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI... 78 3e-13
pir||D81847 proline--tRNA ligase (EC 6.1.1.15) NMA1553 [imported... 78 3e-13
sp|O05947|SYT_RICPR THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI... 76 6e-13
pir||H72368 proline--tRNA ligase (EC 6.1.1.15) - Thermotoga mari... 76 6e-13
sp|P56071|SYT_HELPY THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI... 76 8e-13
sp|P56124|SYP_HELPY PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE... 76 8e-13
sp|Q9ZMV3|SYT_HELPJ THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI... 76 8e-13
pir||F83303 threonyl-tRNA synthetase PA2744 [imported] - Pseudom... 76 8e-13
pir||A82479 threonyl-tRNA synthetase VCA0287 [imported] - Vibrio... 75 2e-12
sp|Q9ZMJ6|SYP_HELPJ PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE... 74 4e-12
sp|O83195|SYP_TREPA PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE... 73 6e-12
sp|O83809|SYT_TREPA THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI... 73 6e-12
sp|P43014|SYT_HAEIN THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LI... 73 7e-12
pir||F70332 proline-tRNA synthetase - Aquifex aeolicus >gi|29830... 72 1e-11
sp|P57333|SYP_BUCAI PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE... 72 1e-11
dbj|BAB06138.1| (AP001515) prolyl-tRNA synthetase [Bacillus halo... 72 2e-11
sp|O05814|SYP_MYCTU PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE... 71 2e-11
pir||C83527 prolyl-tRNA synthetase PA0956 [imported] - Pseudomon... 71 4e-11
>pir||G75072 prolyl-tRNA synthetase (pros) PAB1724 - Pyrococcus abyssi (strain
Orsay) >gi|5458396|emb|CAB49884.1| (AJ248286)
prolyl-tRNA synthetase (proS) [Pyrococcus abyssi]
Length = 480
Score = 993 bits (2539), Expect = 0.0
Identities = 480/480 (100%), Positives = 480/480 (100%)
Query: 1 MVERKRWSENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTG 60
MVERKRWSENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTG
Sbjct: 1 MVERKRWSENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTG 60
Query: 61 HQEVLFPALIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFAL 120
HQEVLFPALIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFAL
Sbjct: 61 HQEVLFPALIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFAL 120
Query: 121 WIRSHADLPFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLE 180
WIRSHADLPFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLE
Sbjct: 121 WIRSHADLPFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLE 180
Query: 181 IFDNLMKRLAIAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYN 240
IFDNLMKRLAIAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYN
Sbjct: 181 IFDNLMKRLAIAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYN 240
Query: 241 ILYEKEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQ 300
ILYEKEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQ
Sbjct: 241 ILYEKEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQ 300
Query: 301 EIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVENSTVVL 360
EIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVENSTVVL
Sbjct: 301 EIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVENSTVVL 360
Query: 361 ARRDKLEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFEDRR 420
ARRDKLEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFEDRR
Sbjct: 361 ARRDKLEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFEDRR 420
Query: 421 GIVEIPWCGEESCGLKMEEELDAKMLGIPYPEEKAKAPEGSRCPVCGRDAKFIARFARTY 480
GIVEIPWCGEESCGLKMEEELDAKMLGIPYPEEKAKAPEGSRCPVCGRDAKFIARFARTY
Sbjct: 421 GIVEIPWCGEESCGLKMEEELDAKMLGIPYPEEKAKAPEGSRCPVCGRDAKFIARFARTY 480
>pir||A71093 proline--tRNA ligase (EC 6.1.1.15) - Pyrococcus horikoshii
>gi|3257420|dbj|BAA30103.1| (AP000004) 480aa long
hypothetical prolyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 480
Score = 940 bits (2404), Expect = 0.0
Identities = 446/480 (92%), Positives = 469/480 (96%)
Query: 1 MVERKRWSENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTG 60
MVERKRWSE FSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIM+NIEKFIHEEMERTG
Sbjct: 1 MVERKRWSEEFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMRNIEKFIHEEMERTG 60
Query: 61 HQEVLFPALIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFAL 120
HQEVLFPALIPETEFKKEAEHIAGFEGEVFW+THAGHEPLDV+L+LRPTSETAMYSMFAL
Sbjct: 61 HQEVLFPALIPETEFKKEAEHIAGFEGEVFWVTHAGHEPLDVRLVLRPTSETAMYSMFAL 120
Query: 121 WIRSHADLPFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLE 180
WIRSHADLPFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLE
Sbjct: 121 WIRSHADLPFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLE 180
Query: 181 IFDNLMKRLAIAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYN 240
IFDNLM++LA+AYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNF+KAYN
Sbjct: 181 IFDNLMRKLALAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFSKAYN 240
Query: 241 ILYEKEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQ 300
ILYEKEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKK +
Sbjct: 241 ILYEKEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKGSE 300
Query: 301 EIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVENSTVVL 360
E VY YA+ IEEELR AGIRV+LD+R+KRPGWKFYDWELKGVPVR+EVGP DV+NSTVVL
Sbjct: 301 EEVYSYAKGIEEELRDAGIRVYLDLRDKRPGWKFYDWELKGVPVRVEVGPIDVQNSTVVL 360
Query: 361 ARRDKLEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFEDRR 420
ARRDKLEKIT+KREELVDKVRELF+DIM++LYERANEWL SHIKRV+TLEEAK FEDRR
Sbjct: 361 ARRDKLEKITVKREELVDKVRELFEDIMEFLYERANEWLESHIKRVDTLEEAKAVFEDRR 420
Query: 421 GIVEIPWCGEESCGLKMEEELDAKMLGIPYPEEKAKAPEGSRCPVCGRDAKFIARFARTY 480
GIVEIPWCGEESCGLKMEEEL+AKMLGIPYPEEKAKAPEGS+CPVCGR+AKFIARFARTY
Sbjct: 421 GIVEIPWCGEESCGLKMEEELEAKMLGIPYPEEKAKAPEGSKCPVCGREAKFIARFARTY 480
>pir||D72460 probable prolyl-tRNA synthetase APE2328 - Aeropyrum pernix (strain
K1) >gi|5106029|dbj|BAA81340.1| (AP000064) 485aa long
hypothetical prolyl-tRNA synthetase [Aeropyrum pernix]
Length = 485
Score = 531 bits (1352), Expect = e-150
Identities = 250/481 (51%), Positives = 343/481 (70%), Gaps = 6/481 (1%)
Query: 4 RKRWSENFSEWFNEVIEEAGILDK-RYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQ 62
R++WS +F WF+ VIE A + D RYPVKGM VW+PYG +I + + + + ++ TGH+
Sbjct: 7 REKWSSDFPRWFDWVIETAEVYDYGRYPVKGMGVWMPYGFQIRRRVLEVVRGLLDSTGHE 66
Query: 63 EVLFPALIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWI 122
EVLFP LIPE ++E+EHI GFEGEV+W+TH G E LDVKL LRPTSET++ M WI
Sbjct: 67 EVLFPLLIPEHLLRRESEHIRGFEGEVYWVTHGGREELDVKLALRPTSETSITYMETFWI 126
Query: 123 RSHADLPFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIF 182
+S+ LP K YQ+V+++RYETK TRP+IR+RE++ F EAHT H FEDAERQ+ E +E++
Sbjct: 127 KSYRQLPKKYYQVVSIFRYETKATRPMIRLREVTTFKEAHTVHESFEDAERQVLEAIEVY 186
Query: 183 DNLMKRLAIAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYNIL 242
+ RL I Y+ISKRPEWDKF GA Y++ + +MPDGR LQIGT+H+ Q+F +A++
Sbjct: 187 KAIFDRLLIPYVISKRPEWDKFAGALYTIAFDTIMPDGRALQIGTVHHLGQSFTRAFDFR 246
Query: 243 YEKEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIP--KKEKQ 300
+ D D+ QT++G+S+R++A++IA+HGDDRG+V+PP++APIQVV++PI +EK+
Sbjct: 247 IQMRDERLDHPWQTSYGVSDRVVASLIAVHGDDRGLVIPPSVAPIQVVVIPITPGDEEKR 306
Query: 301 EIVYEYAREIEEELRTAGIRVHLDMRE-KRPGWKFYDWELKGVPVRIEVGPRDVENSTVV 359
V Y + E L AG+RVH+D RE +RPG KFY WE KGVP+R+E+G R+ E T+
Sbjct: 307 GKVLTYTAKAAEALEKAGLRVHVDDREWERPGAKFYYWEAKGVPIRVEIGLREAEQDTLT 366
Query: 360 LARRDKLEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFEDR 419
+ARRD LEK + E +++REL I + ERA + + R E+LEEA+ E R
Sbjct: 367 IARRDTLEKTEVPLGEAGNRIRELMAQIESSMRERAKSFFGERLLRTESLEEARDWVEGR 426
Query: 420 RGIVEIPWCGEESCGLKMEEELDAKMLGIPYPEEKAKAPEGSRCPVCGRDAKFIARFART 479
RGI EIPWCG ESCGL+MEE ++ K+LG P+PEE + EG RCP+CGR A R A+T
Sbjct: 427 RGIAEIPWCGRESCGLEMEERVNGKVLGTPWPEEPVE--EGKRCPLCGRPAVAWIRLAKT 484
Query: 480 Y 480
Y
Sbjct: 485 Y 485
>sp|O26708|SYP_METTH PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE) (PRORS)
>gi|7449172|pir||C69181 proline--tRNA ligase (EC
6.1.1.15) - Methanobacterium thermoautotrophicum (strain
Delta H) >gi|2621691|gb|AAB85117.1| (AE000842)
prolyl-tRNA synthetase [Methanobacterium
thermoautotrophicum]
Length = 482
Score = 513 bits (1307), Expect = e-144
Identities = 242/461 (52%), Positives = 325/461 (70%), Gaps = 10/461 (2%)
Query: 11 FSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALI 70
FSEWF+ ++EEA I+D+RYPVKGM+VW+P+G I KN K + ++R H+EVLFP L+
Sbjct: 20 FSEWFHNILEEAEIIDQRYPVKGMHVWMPHGFMIRKNTLKILRRILDRD-HEEVLFPLLV 78
Query: 71 PETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPF 130
PE E KEA H+ GFE EV+W+TH G L KL LRPTSET MY MFALW+RSH DLP
Sbjct: 79 PEDELAKEAIHVKGFEDEVYWVTHGGLSKLQRKLALRPTSETVMYPMFALWVRSHTDLPM 138
Query: 131 KVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKRLA 190
+ YQ+VN +RYETKHTRPLIRVREI+ F EAHT HA +AE Q++ +EI+ L
Sbjct: 139 RFYQVVNTFRYETKHTRPLIRVREITTFKEAHTIHATASEAEEQVERAVEIYKEFFNSLG 198
Query: 191 IAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYNILYEKEDGTH 250
I Y+I++RP WDKFPG+ Y++ + +MPDG+TLQIGT+HN Q FA+ + I +E +G H
Sbjct: 199 IPYLITRRPPWDKFPGSEYTVAFDTLMPDGKTLQIGTVHNLGQTFARTFEIKFETPEGDH 258
Query: 251 DYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQEIVYEYAREI 310
+YVHQT +G+S+R++A+VIAIHGD+ G+ LPP +A QVVIVPI K+ E V E RE+
Sbjct: 259 EYVHQTCYGLSDRVIASVIAIHGDESGLCLPPDVAAHQVVIVPIIFKKAAEEVMEACREL 318
Query: 311 EEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVENSTVVLARRDKLEKIT 370
L AG RVHLD R+ R G K+Y+WE++GVP+R+E+GPRD+E V++RRD EK+T
Sbjct: 319 RSRLEAAGFRVHLDDRDIRAGRKYYEWEMRGVPLRVEIGPRDLEKGAAVISRRDTGEKVT 378
Query: 371 IKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFEDRRGIVEIPWCGE 430
+ + + +REL DI++ L RA E + S I+ ETLEEA + +++RGI+ WCGE
Sbjct: 379 ADLQGIEETLRELMKDILENLRTRAWERMESEIREAETLEEASRIVDEKRGIISFMWCGE 438
Query: 431 ESCGLKMEEELDAKMLGIPYPEEKAKAPEGS-RCPVCGRDA 470
E CG+ +EE++ +LGI EGS C CGR+A
Sbjct: 439 EECGMDVEEKVRVDILGI--------QEEGSGTCINCGREA 471
>emb|CAB57731.1| (Y18930) prolyl (glutamyl) tRNA synthetase [Sulfolobus
solfataricus]
Length = 481
Score = 501 bits (1275), Expect = e-140
Identities = 238/483 (49%), Positives = 340/483 (70%), Gaps = 8/483 (1%)
Query: 2 VERKRWSENFSEWFNEVIEEAGILDK-RYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTG 60
+ R++WS+NFSEWF+ V+ E D RYP+KGM VW+PYG K+ +NI I ++ TG
Sbjct: 3 ITREKWSKNFSEWFDWVLREGEFYDYGRYPIKGMGVWMPYGFKLRQNIIGIIRNFLDSTG 62
Query: 61 HQEVLFPALIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFAL 120
H+EVLFP LIPE ++E+ HI GFE EVFW+T G LDVKL LRPTSE A+ +M L
Sbjct: 63 HEEVLFPLLIPEDLLRRESTHIKGFEEEVFWVTKGGSTDLDVKLALRPTSEVAITTMENL 122
Query: 121 WIRSHADLPFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLE 180
W++S+ LP K YQIV+V+RYETK TRP+IR+REI+ F EAHT H ++DA++Q++E +E
Sbjct: 123 WLKSYKQLPKKYYQIVSVFRYETKATRPMIRLREITTFKEAHTVHETYDDAQKQVEEAIE 182
Query: 181 IFDNLMKRLAIAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYN 240
I+ + L I Y++S+RPEWD+F GA ++ + +MPDGR +QIGT+H+ QNF+KA +
Sbjct: 183 IYKKIFDTLTIPYVLSERPEWDRFAGALHTYAFDTIMPDGRAMQIGTVHHLGQNFSKALD 242
Query: 241 ILYEKEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQ 300
+K+DG+ DY HQT++G+S+R +A+VIAIHGDD G VLPP++API+VV++PIP K ++
Sbjct: 243 FKIQKKDGSLDYPHQTSYGISDRAVASVIAIHGDDHGPVLPPSVAPIKVVVIPIPAKNEE 302
Query: 301 EI--VYEYAREIEEELRTAGIRVHLDM-REKRPGWKFYDWELKGVPVRIEVGPRDVENST 357
E V +Y+ EI E I D EK PG KFY WE+KGVP+R+E+GPR++ + T
Sbjct: 303 ETQQVMKYSIEICEMFNKNNITCLTDQDTEKTPGEKFYIWEIKGVPIRLEIGPRELISGT 362
Query: 358 VVLARRDKLEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFE 417
V + RRD + T+++EE ++K++EL ++I + L +A E L S I+ +E+AKK
Sbjct: 363 VFIKRRDNFKSYTVRKEEAINKIKELLNEIQEDLRRKAWEDLKSRIEYSNDIEKAKKILG 422
Query: 418 DRRGIVEIPWCGEESCGLKMEEELDAKMLGIPYPEEKAKAPEGSRCPVCGRDAKFIARFA 477
+ GIVE+PWCG CGLK+EE +A++LG YP EK + +C +C +AK + R A
Sbjct: 423 NNSGIVEVPWCGSNECGLKIEELTNARVLG--YPIEKREV--NDKCVICKMNAKTVLRIA 478
Query: 478 RTY 480
+TY
Sbjct: 479 KTY 481
>gb|AAK40884.1| Prolyl -tRNA synthetase (proS) [Sulfolobus solfataricus]
Length = 481
Score = 501 bits (1275), Expect = e-140
Identities = 238/483 (49%), Positives = 340/483 (70%), Gaps = 8/483 (1%)
Query: 2 VERKRWSENFSEWFNEVIEEAGILDK-RYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTG 60
+ R++WS+NFSEWF+ V+ E D RYP+KGM VW+PYG K+ +NI I ++ TG
Sbjct: 3 ITREKWSKNFSEWFDWVLREGEFYDYGRYPIKGMGVWMPYGFKLRQNIIGIIRNFLDSTG 62
Query: 61 HQEVLFPALIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFAL 120
H+EVLFP LIPE ++E+ HI GFE EVFW+T G LDVKL LRPTSE A+ +M L
Sbjct: 63 HEEVLFPLLIPEDLLRRESTHIKGFEEEVFWVTKGGSTDLDVKLALRPTSEVAITTMENL 122
Query: 121 WIRSHADLPFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLE 180
W++S+ LP K YQIV+V+RYETK TRP+IR+REI+ F EAHT H ++DA++Q++E +E
Sbjct: 123 WLKSYKQLPKKYYQIVSVFRYETKATRPMIRLREITTFKEAHTVHETYDDAQKQVEEAIE 182
Query: 181 IFDNLMKRLAIAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYN 240
I+ + L I Y++S+RPEWD+F GA ++ + +MPDGR +QIGT+H+ QNF+KA +
Sbjct: 183 IYKKIFDTLTIPYVLSERPEWDRFAGALHTYAFDTIMPDGRAMQIGTVHHLGQNFSKALD 242
Query: 241 ILYEKEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQ 300
+K+DG+ DY HQT++G+S+R +A+VIAIHGDD G VLPP++API+VV++PIP K ++
Sbjct: 243 FKIQKKDGSLDYPHQTSYGISDRAVASVIAIHGDDHGPVLPPSVAPIKVVVIPIPAKNEE 302
Query: 301 EI--VYEYAREIEEELRTAGIRVHLDM-REKRPGWKFYDWELKGVPVRIEVGPRDVENST 357
E V +Y+ EI E I D EK PG KFY WE+KGVP+R+E+GPR++ + T
Sbjct: 303 ETQQVMKYSIEICEMFNKNNITCLTDQDTEKTPGEKFYIWEIKGVPIRLEIGPRELISGT 362
Query: 358 VVLARRDKLEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFE 417
V + RRD + T+++EE ++K++EL ++I + L +A E L S I+ +E+AKK
Sbjct: 363 VFIKRRDNFKSYTVRKEEAINKIKELLNEIQEDLRRKAWEDLKSRIEYSNDIEKAKKILG 422
Query: 418 DRRGIVEIPWCGEESCGLKMEEELDAKMLGIPYPEEKAKAPEGSRCPVCGRDAKFIARFA 477
+ GIVE+PWCG CGLK+EE +A++LG YP EK + +C +C +AK + R A
Sbjct: 423 NNSGIVEVPWCGSNECGLKIEELTNARVLG--YPIEKREV--NDKCVICKMNAKTVLRIA 478
Query: 478 RTY 480
+TY
Sbjct: 479 KTY 481
>emb|CAC12066.1| (AL445066) prolyl-tRNA synthetase related protein [Thermoplasma
acidophilum]
Length = 462
Score = 495 bits (1260), Expect = e-139
Identities = 244/473 (51%), Positives = 326/473 (68%), Gaps = 17/473 (3%)
Query: 9 ENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPA 68
ENFSEW+NE+I A + DKRYPVKGMNVWLPYG KIM I+ + +++ QEV FP
Sbjct: 6 ENFSEWYNEIITLAELSDKRYPVKGMNVWLPYGWKIMSLIDSIVRRAVDKRNFQEVNFPI 65
Query: 69 LIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADL 128
LI + + E EHI GFE E++W+T G E L+ +L LRPTSE+AMY MF+LWIRSHADL
Sbjct: 66 LIGRSMLEVEFEHIRGFENEIYWVTKGGKEKLEEELALRPTSESAMYPMFSLWIRSHADL 125
Query: 129 PFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKR 188
P K+YQIV+VYRYETKHTR IR+REI FFEAHTAHA +EDAE Q+ + EI+ +
Sbjct: 126 PLKIYQIVSVYRYETKHTRSFIRIREI-HFFEAHTAHATYEDAEAQMDQYKEIWREISSL 184
Query: 189 LAIAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYNILYEKEDG 248
L + Y +RP+WDKFPGA Y++ + V+P GR+LQIGT+H Y NF+K Y+I Y KEDG
Sbjct: 185 LCLPYFYDQRPDWDKFPGAMYTIAFDTVLPSGRSLQIGTIHQYGTNFSKNYDIKYLKEDG 244
Query: 249 THDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQEIVYEYAR 308
T DY HQTT+GMSERLLAA+I IHGDD+G+VLPP +APIQV+I+PIP V EYAR
Sbjct: 245 TFDYAHQTTYGMSERLLAAIIGIHGDDKGLVLPPDVAPIQVIIIPIPGAG----VMEYAR 300
Query: 309 EIEEELRTAGIRVHLDMREK-RPGWKFYDWELKGVPVRIEVGPRDVENSTVVLARRDKLE 367
++E L + IRV +D RE PG+KF DWE++GVP+RIE+G R+V+N T+ ++ R+
Sbjct: 301 DVENTLNSINIRVKVDDRENYTPGYKFNDWEMRGVPLRIEIGEREVKNRTLTISMRNIQG 360
Query: 368 KITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFEDRRGIVEIPW 427
K+TI+R +L+ +V + I + + E A + H+ R LEE +R G++ W
Sbjct: 361 KLTIERSKLIYEVPDTLIRIREKMMENAQKVFKDHVFRATKLEEF-----NRDGLITAFW 415
Query: 428 CGEESCGLKMEEELDAKMLGIPYPEEKAKAPEGSRCPVCGRDAKFIARFARTY 480
CG + C K+E E + +LG + E +C VCG++ K +A F+R+Y
Sbjct: 416 CGSKECSDKIEAETEKSVLGF-----MVDSSETGKCVVCGKNGK-MAVFSRSY 462
>gi|11499201 prolyl-tRNA synthetase (proS) [Archaeoglobus fulgidus]
>gi|3334358|sp|O28664|SYP_ARCFU PROLYL-TRNA SYNTHETASE
(PROLINE--TRNA LIGASE) (PRORS) >gi|7449173|pir||H69450
prolyl-tRNA synthetase (proS) homolog - Archaeoglobus
fulgidus >gi|2648947|gb|AAB89637.1| (AE000991)
prolyl-tRNA synthetase (proS) [Archaeoglobus fulgidus]
Length = 575
Score = 481 bits (1225), Expect = e-135
Identities = 245/475 (51%), Positives = 322/475 (67%), Gaps = 13/475 (2%)
Query: 9 ENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPA 68
ENFSEW++EVI+ A I+D RYPVKG+ VW P+G KI + + + E M+R H EV FPA
Sbjct: 111 ENFSEWYHEVIQTAEIMDVRYPVKGLYVWFPFGFKIRQLVYSKLREIMDRE-HDEVYFPA 169
Query: 69 LIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADL 128
LIPETE KE EHI GFE EV+WITH G PLDVKL LRPTSETAMY MF LW+R+HADL
Sbjct: 170 LIPETELGKEGEHIKGFEDEVYWITHGGLTPLDVKLALRPTSETAMYPMFRLWVRNHADL 229
Query: 129 PFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKR 188
P KVYQIVN +RYETKHTRPLIR+REI+ F EAHT H DFE+A +K+ + +
Sbjct: 230 PLKVYQIVNTFRYETKHTRPLIRLREITSFKEAHTVHKDFEEAAEHVKKAIGFYKEFYDF 289
Query: 189 LAIAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYNILYEKEDG 248
LAI Y++ +RPEWDKFPGA Y++ + +MPDGRTLQIGT+H+ NFA+ ++I YE +G
Sbjct: 290 LAIPYMVIRRPEWDKFPGAAYTIAFDTIMPDGRTLQIGTVHHLADNFARTFDIKYEAPNG 349
Query: 249 THDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQEIVYEYAR 308
H Y HQT +G+SER +AA+I++HGDD G+VLP +AP+Q+VI+PI K K+E V E R
Sbjct: 350 EHYYAHQTCYGISERCIAALISVHGDDLGLVLPFEVAPVQIVIIPILYKGKEEAVMEACR 409
Query: 309 EIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVENSTVVLARRDKLEK 368
++ E+L+ RV LD E RPG K+Y WELKGVP+R E+GPRD E V++ RD+ K
Sbjct: 410 KLAEKLK--AFRVVLDEGEDRPGAKYYKWELKGVPIRFEIGPRDAEKGVAVVSFRDEKRK 467
Query: 369 ITIKREELVD-KVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFEDRRGIVEIPW 427
+ +E+ + KV E ++ + L A E + +K VE E E+ G+V +
Sbjct: 468 FEVPLDEVDEGKVLEWARELKQRLRNAAAERMAEKVKFVENTGE----IEEWGGVVAVYL 523
Query: 428 CGEESCGLKMEEELDAKMLG--IPYPEEKAKAPEGSRCPVCGRDAKFIARFARTY 480
C +E CG +EE +LG P+ PEG +C VCGR+ + +A A+TY
Sbjct: 524 CSDEDCGHSVEEH-GKSLLGWFEEVPDWLDLEPEG-KCVVCGREGR-LAALAKTY 575
>sp|Q58635|SYP_METJA PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE) (PRORS)
>gi|2129222|pir||E64454 proline--tRNA ligase (EC
6.1.1.15) - Methanococcus jannaschii
>gi|1591870|gb|AAB99242.1| (U67564) prolyl-tRNA
synthetase (proS) [Methanococcus jannaschii]
Length = 455
Score = 477 bits (1215), Expect = e-133
Identities = 225/439 (51%), Positives = 314/439 (71%), Gaps = 4/439 (0%)
Query: 11 FSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALI 70
FSEW+++++E+A I D RYP+KG V+LPYG KI + + I ++ +GH E LFP LI
Sbjct: 3 FSEWYSDILEKAEIYDVRYPIKGCGVYLPYGFKIRRYTFEIIRNLLDESGHDEALFPMLI 62
Query: 71 PETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPF 130
PE KEAEHI GFE EV+W+TH G LDVKL LRPTSET +Y M LW++ H DLP
Sbjct: 63 PEDLLAKEAEHIKGFEDEVYWVTHGGKTQLDVKLALRPTSETPIYYMMKLWVKVHTDLPI 122
Query: 131 KVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKRLA 190
K+YQIVN +RYETKHTRPLIR+REI F EAHTAH+ E+AE Q+KE + I+ L
Sbjct: 123 KIYQIVNTFRYETKHTRPLIRLREIMTFKEAHTAHSTKEEAENQVKEAISIYKKFFDTLG 182
Query: 191 IAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYNILYEKEDGTH 250
I Y+ISKRPEWDKFPGA Y++ + + PDGRT+QI T+HN QNF+K + I++E G
Sbjct: 183 IPYLISKRPEWDKFPGAEYTMAFDTIFPDGRTMQIATVHNLGQNFSKTFEIIFETPTGDK 242
Query: 251 DYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQEIVYEYAREI 310
DY +QT +G+S+R++A++IAIHGD++G++LPP +APIQVVIVP+ K K++IV E A+EI
Sbjct: 243 DYAYQTCYGISDRVIASIIAIHGDEKGLILPPIVAPIQVVIVPLIFKGKEDIVMEKAKEI 302
Query: 311 EEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVENSTVVLARRDKLEKIT 370
E+L+ RVH+D R+ RPG KF DWE+KGVP+RIEVGP+D+EN + L RRD +EK
Sbjct: 303 YEKLK-GKFRVHIDDRDIRPGRKFNDWEIKGVPLRIEVGPKDIENKKITLFRRDTMEKFQ 361
Query: 371 IKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETL--EEAKKAFEDRRGIVEIPWC 428
+ +L++ V + ++IM+ + RA E + I +E + +E K ++RG++ +P+
Sbjct: 362 VDETQLMEVVEKTLNNIMENIKNRAWEKFENFITILEDINPDEIKNILSEKRGVILVPF- 420
Query: 429 GEESCGLKMEEELDAKMLG 447
EE ++EE+++A +LG
Sbjct: 421 KEEIYNEELEEKVEATILG 439
>gb|AAG28517.1|AF197899_1 (AF197899) prolyl-tRNA synthetase [Methanococcus maripaludis]
Length = 460
Score = 455 bits (1159), Expect = e-127
Identities = 219/452 (48%), Positives = 312/452 (68%), Gaps = 11/452 (2%)
Query: 11 FSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALI 70
FSEW+++++E+AGI D RYP+KG V+LPYG KI + + + + ++ TGH E LFP LI
Sbjct: 3 FSEWYSDILEKAGIYDLRYPIKGCGVYLPYGFKIRRYSFEILRKLLDETGHDETLFPMLI 62
Query: 71 PETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPF 130
PE KE EHI GFE EVFW+TH G PL+VKL LRPTSET MY M WI+ H DLP
Sbjct: 63 PENLLAKEGEHIKGFEDEVFWVTHGGKTPLEVKLALRPTSETTMYYMMKQWIKVHTDLPL 122
Query: 131 KVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKRLA 190
K+YQ+VN +RYETKHTRPLIR+REI F EAHTAHA ++ + QI+E L ++ +
Sbjct: 123 KLYQVVNTFRYETKHTRPLIRLREIMSFKEAHTAHATKKECDAQIEEALTLYKAFFDEIG 182
Query: 191 IAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYNILYEKEDGTH 250
+ Y+ISKRPEWDKFPGA Y++ + + PDG+T+QIGT+HN QNFAK + + +E DG
Sbjct: 183 VPYVISKRPEWDKFPGADYTMAFDTIYPDGKTMQIGTVHNLGQNFAKTFELEFETPDGEK 242
Query: 251 DYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQEIVYEYAREI 310
D+V+QT +G+S+R +A++I++HGD++G+V+P +APIQ+V++P+ K K+EIV + +E+
Sbjct: 243 DFVYQTCYGISDRAIASLISVHGDEKGLVIPVDVAPIQIVLIPLLFKGKEEIVMDKIKEL 302
Query: 311 EEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVENSTVVLARRDKLEKIT 370
+ L++ RVHLD R+ RPG K+ DWELKGVP+RIE+GPRD+EN ++ RRD EKIT
Sbjct: 303 NKTLKSE-FRVHLDDRDIRPGRKYNDWELKGVPLRIELGPRDIENGHALIVRRDTGEKIT 361
Query: 371 IKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVE-------TLEEAKKAFEDRRGIV 423
++ ++++V ++ L +A E + S I V+ E+ K + +GI+
Sbjct: 362 VEYSNILEEVEKIVSMYKDNLKIKAEEKIKSFITVVDFESDVNALSEKVKAELLENKGII 421
Query: 424 EIPWCGEESC-GLKMEEELDAKMLGIPYPEEK 454
IP+ EES + EE +DA +LG+ E K
Sbjct: 422 LIPF--EESIYNEEFEELIDASVLGLTTYEGK 451
>emb|CAB71307.1| (AJ130879) prolyl tRNA synthetase [Clostridium sticklandii]
Length = 481
Score = 355 bits (901), Expect = 7e-97
Identities = 188/474 (39%), Positives = 280/474 (58%), Gaps = 11/474 (2%)
Query: 9 ENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPA 68
E+F +W+ +VI + ++D PVKG V PYG I +NI+ F+ + TGHQ FP
Sbjct: 17 EDFPQWYTDVITKTDLVDYS-PVKGFMVIKPYGYAIWENIQAFLDRRFKETGHQNCYFPL 75
Query: 69 LIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADL 128
LIPE+ KE EH+ GF EV W+TH G E L +L +RPTSET + SM++ W+ S+ +L
Sbjct: 76 LIPESLLNKEKEHVEGFAPEVAWVTHGGSEKLAERLCVRPTSETIICSMYSKWLTSYREL 135
Query: 129 PFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMK- 187
P+ Q +V R+E K TRP +R E + E HT H E+A+ + + L I+ + +
Sbjct: 136 PYLYNQWCSVVRWE-KSTRPFLRTSEF-LWQEGHTLHETAEEAQAETLQMLAIYKEMAED 193
Query: 188 RLAIAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYNILYEKED 247
LAI + ++ + ++F GA + E +M DG+ LQ GT HN Q+F KA++I ++
Sbjct: 194 LLAIPVVDGRKSDRERFAGAAATYTIEALMHDGKALQSGTSHNLAQHFTKAFDITFQGRT 253
Query: 248 GTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQEIVYEYA 307
G +Y H T++G S RL+ +I +HGD+RG+VLPP +AP QVVI+PI + +E V + A
Sbjct: 254 GELEYPHHTSWGASTRLIGGIIMVHGDNRGLVLPPRVAPTQVVIIPI--AQNKEGVLDKA 311
Query: 308 REIEEELRTAGIRVHL-DMREKRPGWKFYDWELKGVPVRIEVGPRDVENSTVVLARRDKL 366
EI++EL GIRV L D PGWKF +E+KGVP+R+E+GPRD+EN+ ++ARRD L
Sbjct: 312 YEIKKELEAKGIRVTLDDDTNYSPGWKFNQYEMKGVPLRLEIGPRDIENNVAMIARRDTL 371
Query: 367 EKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFEDRRGIVEIP 426
K + + + D V+ L D + + ERA +S + EE K+ + G +
Sbjct: 372 SKDSYSLDNIGDTVKNLLDTVHTDMLERARAHRDSKTFTFKDYEEFKRKMIETPGFAKGM 431
Query: 427 WCGEESCGLKMEEELDAKMLGIPYPEEKAKAPEGSRCPVCGRDAKFIARFARTY 480
WCGEE C K++E+ + IP+ +E G C CG+ AK + A+ Y
Sbjct: 432 WCGEEECEAKIKEDTGVTIRCIPFVQENL----GETCQFCGKPAKHMVYLAKAY 481
>gb|AAG23138.2|AF245446_1 (AF245446) prolyl-tRNA synthetase [Giardia intestinalis]
Length = 542
Score = 325 bits (825), Expect = 6e-88
Identities = 192/498 (38%), Positives = 283/498 (56%), Gaps = 27/498 (5%)
Query: 9 ENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPA 68
+ F++WF+ +++ A ++D+RYPVKG V+ PYG + I + EE + G ++LFP
Sbjct: 46 DTFADWFDAIMDAAELVDRRYPVKGCVVFRPYGFFMENAIMRLCEEEYAKVGISQILFPT 105
Query: 69 LIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADL 128
+IPE+ KKE++HI GFE E FW+ G +PL+ +L LRPTSETA+YSMF+ W+RS+ DL
Sbjct: 106 VIPESFLKKESDHIKGFEAECFWVEKGGLQPLEERLALRPTSETAIYSMFSKWVRSYKDL 165
Query: 129 PFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMK- 187
P K++Q ++R+ETK+T+PLIRVREI + EAH HA EDA Q+ + ++ D +
Sbjct: 166 PLKIHQTCTIFRHETKNTKPLIRVREI-HWNEAHCCHATAEDAVSQLSDYWKVIDTIFSD 224
Query: 188 RLAIAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYNILYEKED 247
L +R WD+FPGA YS ++VVMP GR LQ +HN Q F+ ++ILY +
Sbjct: 225 ELCFKGQKLRRVCWDRFPGADYSEVSDVVMPCGRVLQTAGIHNLGQRFSSTFDILYANKA 284
Query: 248 GTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPI--PKKEKQEI--- 302
+ + T G+S R+LA ++IHGD G+VLPP IAPI VVI+PI KK QE
Sbjct: 285 NESVHPYLTCAGISTRVLACALSIHGDSGGLVLPPLIAPIHVVIIPIGCGKKNNQESDQQ 344
Query: 303 VYEYAREIEEELRT-AGIRVHLDMR-EKRPGWKFYDWELKGVPVRIEVGPRDVENSTVVL 360
V EI + L++ G+RV +D K G K Y +ELKGVP+RIEVG RD+ N ++
Sbjct: 345 VLGKVNEIADTLKSKLGLRVSIDDDFSKSMGDKLYYYELKGVPLRIEVGQRDLANGQCIV 404
Query: 361 ARRD---------------KLEKITIKREELVDK--VRELFDDIMKYLYERANEWLNSHI 403
RD K+ T + ELV K +++ D L E+A + NS +
Sbjct: 405 VPRDVGKDQKRVIPITEVMKVSSHTTENHELVVKNVIKDELDAYKARLKEKAFAFHNSMV 464
Query: 404 KRVETLEEAKKAFEDRRGIVEIPWCGEESCGLKMEEEL-DAKMLGIPYPEEKAKAPEGSR 462
++ +E E++ G+ P+ E+ G +++L DA I G
Sbjct: 465 TNCKSFDEIVACIENKGGLARFPFYTTEADGEVWDKKLKDACSAEIRGHNPDENVLPGEV 524
Query: 463 CPVCGRDAKFIARFARTY 480
C + G+ A A++Y
Sbjct: 525 CALSGKPAVCYMYCAKSY 542
>dbj|BAB10183.1| (AP000378) prolyl tRNA synthetase [Arabidopsis thaliana]
Length = 543
Score = 322 bits (817), Expect = 5e-87
Identities = 184/482 (38%), Positives = 287/482 (59%), Gaps = 17/482 (3%)
Query: 8 SENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFP 67
S++F+ W+ +VI A + D PV+G V PYG I + I+ +++ + + TGH + FP
Sbjct: 70 SQDFNAWYLDVIASAELADYG-PVRGTMVIRPYGYAIWEAIQDYLNVKFKETGHSNMYFP 128
Query: 68 ALIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHAD 127
IP + +KEA H+ GF E+ +T G + L+ KL++RPTSET + MF WI S+ D
Sbjct: 129 QFIPYSFIEKEASHVEGFSPELALVTVGGGKELEEKLVVRPTSETIVNHMFTQWIHSYRD 188
Query: 128 LPFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNL-M 186
LP + Q NV R+E + T+P IR E + E HTAHA E+AE++ K+ +EI+
Sbjct: 189 LPLMINQWANVTRWEMR-TKPFIRTLEF-LWQEGHTAHATPEEAEKEAKQMIEIYTRFAF 246
Query: 187 KRLAIAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYNILYEKE 246
++ AI I ++ + + F GA + E +M D + LQ GT HN QNF++A+ + E
Sbjct: 247 EQTAIPVIPGRKSKLETFAGADITYTIEAMMGDRKALQAGTSHNLGQNFSRAFGTQFADE 306
Query: 247 DGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQEI-VYE 305
+G +V QT++ +S R + +I HGDD G++LPP IAPIQVVIVPI KK+ ++ V
Sbjct: 307 NGERQHVWQTSWAVSTRFVGGIIMTHGDDTGLMLPPKIAPIQVVIVPIWKKDTEKTGVLS 366
Query: 306 YAREIEEELRTAGIRVHLDMREKR-PGWKFYDWELKGVPVRIEVGPRDVENSTVVLARRD 364
A ++E L+TAG+RV LD ++R PGWKF WE+KG+P+RIE+GPRDV +++VV++RRD
Sbjct: 367 AASSVKEALQTAGVRVKLDDTDQRTPGWKFNFWEMKGIPLRIEIGPRDVSSNSVVVSRRD 426
Query: 365 ------KLEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFED 418
K+ I+++ LV V+E D+I L E+A + +S+I V + E K A
Sbjct: 427 VPGKAGKVFGISMEPSTLVAYVKEKLDEIQTSLLEKALSFRDSNIVDVNSYAELKDAISS 486
Query: 419 RRGIVEIPWCGEESCGLKMEEELDAKMLGIPYPEEKAKAPEGSRCPVCGRDAKFIARFAR 478
+ PW ++ +++EE A + P+ + + C + G A+ +A FA+
Sbjct: 487 GKW-ARGPWSASDADEQRVKEETGATIRCFPFEQTQGT----KTCLMTGNPAEEVAIFAK 541
Query: 479 TY 480
+Y
Sbjct: 542 SY 543
>emb|CAB36573.1| (AL035472) putative prolyl tRNA synthetase [Mycobacterium leprae]
Length = 473
Score = 318 bits (806), Expect = 1e-85
Identities = 180/481 (37%), Positives = 271/481 (55%), Gaps = 16/481 (3%)
Query: 6 RWSENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVL 65
R ++FS W+NEV+ +AG++D R P KG V PYG +I + ++ + +++ GH+
Sbjct: 3 RQEDDFSAWYNEVVAKAGLID-RGPAKGTMVIRPYGYRIWELLQDELDSKIKELGHENAY 61
Query: 66 FPALIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSH 125
FP LIPE F +EAEH+ GF E+ +THAG + L L++RPTSET + M A WI SH
Sbjct: 62 FPMLIPENYFNREAEHVEGFHPELAVVTHAGGKELSEPLVIRPTSETVIGDMMAKWITSH 121
Query: 126 ADLPFKVYQIVNVYRYETKHTRPLIRVREISRFF-EAHTAHADFEDAERQIKEDLEIFDN 184
DLP ++ Q NV R+E RP + +R I + E H+AH + DA R+ L+I+
Sbjct: 122 RDLPLRLNQWSNVVRWEL---RPRMLLRTIEFLWQEGHSAHIEKSDALRETLFALDIYTT 178
Query: 185 LMKRLAIAYIIS-KRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYNILY 243
L + +A I+S ++ ++F GA + E +M DG+ LQ T H NFA+A+NI Y
Sbjct: 179 LARDMAAIPIVSGEKTAGERFAGALNTYTIEAMMRDGKALQSATTHYLGDNFARAFNIRY 238
Query: 244 EKEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQEIV 303
+ +VH T+FG+S R++ A++ +HGDD+G+VLPP +AP QVVIVPI K V
Sbjct: 239 TTAEEQQAFVHTTSFGLSTRMIGAIVMVHGDDKGLVLPPQVAPYQVVIVPITTGNKASEV 298
Query: 304 YEYAREIEEELRTAGIRVHLDMR-EKRPGWKFYDWELKGVPVRIEVGPRDVENSTVVLAR 362
A ++ L+ AG+R H+D R + PGWK+ +WEL+GVP+R+E+GPRD+E T V+ R
Sbjct: 299 GHAAADLARRLQAAGVRTHVDARPQLTPGWKYNEWELRGVPIRLELGPRDLEAGTTVMVR 358
Query: 363 R-DKLEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFEDRRG 421
R + K I ++ + ++ + L ERA ++ + H V+ + A G
Sbjct: 359 RIGEKAKQPIAIAAAPTELPGILEEFQRTLLERATQFRDDHTTLVDNWDAF--ATTVATG 416
Query: 422 IVEIPWCGEESCGLKMEEELDAKMLGIPYPEEKAKAPEGSRCPVCGRDAKFIAR--FART 479
CG C EE++ A+ P + AP RC C + + R FAR
Sbjct: 417 WALAIHCGNPEC----EEDIKAETAATPRCVPRQGAPATGRCIRCDAPSAYDKRVIFARA 472
Query: 480 Y 480
Y
Sbjct: 473 Y 473
>gb|AAG18956.1| (AE004997) proline-tRNA synthetase; ProS [Halobacterium sp. NRC-1]
Length = 465
Score = 316 bits (800), Expect = 5e-85
Identities = 166/464 (35%), Positives = 265/464 (56%), Gaps = 17/464 (3%)
Query: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
G V P G + + I+ + + TG + FP IPE ++E + + GF+ EV W+
Sbjct: 3 GFIVTRPRGYALWEAIQDNLDGWFKDTGVENAYFPMFIPEDYLEREKDIVEGFDPEVAWV 62
Query: 93 THAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHTRPLIRV 152
T GH+ LD +L +RPTSE+ + + W+RSH DLP +V Q +V R+E T+P R
Sbjct: 63 TQGGHDDLDQRLAVRPTSESIIAPYLSQWVRSHRDLPLRVNQWNSVVRWEATETKPFFRT 122
Query: 153 REISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKR-LAIAYIISKRPEWDKFPGAFYSL 211
+E + E HTAHA E A + L+ + L + L I + ++P+ DKFPGA ++
Sbjct: 123 KEFL-WQEGHTAHATDEAAWAETTLRLDQYHRLYEDVLGIPVLRGRKPDHDKFPGADTTM 181
Query: 212 GAEVVMPDGRTLQIGTMHNYKQNFAKAYNILYEKEDGTHDYVHQTTFGMSERLLAAVIAI 271
E +MPDG+++Q GT H+ Q+FA A++I + ED + T++G+S R + A++
Sbjct: 182 SVEALMPDGKSVQGGTSHHLGQSFADAFDITFADEDEAERTAYTTSWGLSWRAIGALVMS 241
Query: 272 HGDDRGMVLPPTIAPIQVVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKR-P 330
H DD+G+VLPPT+AP QVVIVPI +++ ++ V +Y EI EL G+RVH D R+ R P
Sbjct: 242 HSDDQGLVLPPTVAPKQVVIVPIWQEDTKDDVEQYGAEIAAELEAQGVRVHFDDRDGRNP 301
Query: 331 GWKFYDWELKGVPVRIEVGPRDVENSTVVLARRDKLEKITIKREELVDKVRELFDDIMKY 390
G+KF +WEL GVPVR E+GP +VE+ V + R E R + D+V + D++
Sbjct: 302 GFKFNEWELNGVPVRFEIGPNEVEDDEVTVVHRPDGESTVEDRAAIADRVHDHLDEVYDK 361
Query: 391 LYERANEWLNSHIKRVETLEEAKKAFEDRRGIVEIPWCGEESCGLKMEEELDAKMLGIPY 450
LY+ A + L +++ + + G V+ PWCG++ C ++++++ A+++ +P
Sbjct: 362 LYDAAADRLAENVREADNRADILGTIGQHGGYVKAPWCGDQDCEAEIKDQIAAEIVMVPL 421
Query: 451 PEEKA----------KAPE----GSRCPVCGRDAKFIARFARTY 480
E+ A + PE G C +CG +A A FA++Y
Sbjct: 422 GEDSAARAASELEGERVPEPDHDGEDCAICGDEATRTAYFAKSY 465
>pir||D75416 prolyl-tRNA synthetase - Deinococcus radiodurans (strain R1)
>gi|6459012|gb|AAF10837.1|AE001974_2 (AE001974)
prolyl-tRNA synthetase [Deinococcus radiodurans]
Length = 499
Score = 315 bits (799), Expect = 6e-85
Identities = 165/478 (34%), Positives = 284/478 (58%), Gaps = 9/478 (1%)
Query: 8 SENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFP 67
S +F++W+NEV+++A + D PV G V PYG + +NI++++ + + +GH+ ++FP
Sbjct: 26 SVDFNDWYNEVVKKADLADNS-PVAGAMVVRPYGSALWENIQRWLDDRFKASGHESLIFP 84
Query: 68 ALIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHAD 127
LIP KEA+H+ GF E+F + G E L ++RPTSET + M++ W+ S+ D
Sbjct: 85 TLIPMNFIMKEADHVEGFAPELFTVNKIGTEELAEPYVMRPTSETIIGHMWSGWLNSYRD 144
Query: 128 LPFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMK 187
LPF YQ +V+R E + T+ +R E + E HTAHAD +A ++++ L+++ +
Sbjct: 145 LPFLHYQWGSVFRAELR-TKAFLRTSEFF-WHEGHTAHADEAEARAEVRQQLDLYHEFCR 202
Query: 188 R-LAIAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYNILYEKE 246
LA+ + ++ ++F GA + E +M DG+ LQ GT H QNF++A+++ Y+
Sbjct: 203 DVLALPVVRGEKTASERFAGAVATYSIEGMMRDGKALQSGTSHYLGQNFSRAFDVKYQTR 262
Query: 247 DGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQEIVYEY 306
+ ++ H T++ +S R++ A+I HGDD G+++PP IAPIQVV++P+ +K+ + + +
Sbjct: 263 EQKEEFAHTTSWAISSRIIGAIIMTHGDDSGLMMPPRIAPIQVVVIPVGRKDNFDQMVQE 322
Query: 307 AREIEEELRTAGIRVHLDMRE-KRPGWKFYDWELKGVPVRIEVGPRDVENSTVVLARRDK 365
++ ELR G+RV +D R+ G+K+ DWELKGVPVRIE+GPRD+E+ +V+ R
Sbjct: 323 GEKLAAELRAQGLRVKVDGRDGVTNGFKYNDWELKGVPVRIELGPRDLESGVLVVKNRHS 382
Query: 366 LEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFEDRRGIVEI 425
+K T+ R E V + D I +L +RA ++L ++ V++ + ++ E V
Sbjct: 383 EDKETLPRAEAVSGMSARLDTIHDFLMKRATDFLLANTAEVDSYDAFQREIEAGHW-VRA 441
Query: 426 PWCGEESCGLKMEEELDAKMLGIPYPEEKAKAPEG-SRCPVCGRDAKFIAR--FARTY 480
CGE +C ++E+ A +P+ + + A G +C CG+ + + R F R Y
Sbjct: 442 YHCGEPACEKSIKEDTKATARNVPFDDAEFFAERGEGQCVKCGQPSAYGKRVLFGRQY 499
>pir||T48004 multifunctional aminoacyl-tRNA ligase-like protein - Arabidopsis
thaliana >gi|6899922|emb|CAB71872.1| (AL138651)
multifunctional aminoacyl-tRNA ligase-like protein
[Arabidopsis thaliana]
Length = 530
Score = 312 bits (790), Expect = 7e-84
Identities = 173/483 (35%), Positives = 274/483 (55%), Gaps = 19/483 (3%)
Query: 9 ENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPA 68
ENF EW++EV ++ I + Y + G + P+ + I + ++ F E+++ + FP
Sbjct: 56 ENFGEWYSEVCKQDMI--EYYDISGCYILRPWSMAIWEIMQIFFDAEIKKMKVKNCYFPL 113
Query: 69 LIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADL 128
+ +KE +HI GF EV W+T +G L+V + +RPTSET MY ++ WIR H DL
Sbjct: 114 FVSPGVLEKEKDHIEGFAPEVAWVTKSGKSDLEVPIAIRPTSETVMYPYYSKWIRGHRDL 173
Query: 129 PFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKR 188
P K+ Q NV R+E + P IR RE + E HTA A +A+ ++ + LE++ + +
Sbjct: 174 PLKLNQWCNVVRWEFSNPTPFIRSREF-LWQEGHTAFATKAEADEEVLQILELYRRIYEE 232
Query: 189 -LAIAYIISKRPEWDKFPGAFYSLGAEVVMPD-GRTLQIGTMHNYKQNFAKAYNILYEKE 246
LA+ + + E +KF G Y+ E +P+ GR +Q T H QNFAK + I +E E
Sbjct: 233 YLAVPVVKGMKSENEKFAGGLYTTSVEAFIPNTGRGVQGATSHCLGQNFAKMFEINFENE 292
Query: 247 DGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKE-KQEIVYE 305
+ V Q ++ S R + +I HGDD+G+VLPP +A +QVV++P+P K+ + +Y+
Sbjct: 293 KAETEMVWQNSWAYSTRTIGVMIMTHGDDKGLVLPPKVASVQVVVIPVPYKDANTQGIYD 352
Query: 306 YAREIEEELRTAGIRVHLDMREK-RPGWKFYDWELKGVPVRIEVGPRDVENSTVVLARRD 364
L AGIR D+R+ PGWK+ DWE+KGVP+RIE+GPRD+EN V RRD
Sbjct: 353 ACTATASALCEAGIRAEEDLRDNYSPGWKYSDWEMKGVPLRIEIGPRDLENDQVRTVRRD 412
Query: 365 KLEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFEDRRGIVE 424
K I R LV+ V+EL + I + +YE A + + ++ V+T +E KA +++ ++
Sbjct: 413 NGVKEDIPRGSLVEHVKELLEKIQQNMYEVAKQKREACVQEVKTWDEFIKALNEKK-LIL 471
Query: 425 IPWCGEESCGLKMEEELDAKMLG-------IPYPEEKAKAPEGSRCPVCGRDAKFIARFA 477
PWC EE ++E ++ A+ G + P ++ + PEG+ C G+ AK +
Sbjct: 472 APWCDEE----EVERDVKARTKGETGAAKTLCSPFDQPELPEGTLCFASGKPAKKWTYWG 527
Query: 478 RTY 480
R+Y
Sbjct: 528 RSY 530
>gi|4758294 glutamyl-prolyl tRNA synthetase; glutamate tRNA ligase [Homo sapiens]
>gi|135104|sp|P07814|SYEP_HUMAN MULTIFUNCTIONAL
AMINOACYL-TRNA SYNTHETASE [INCLUDES: GLUTAMYL-TRNA
SYNTHETASE (GLUTAMATE--TRNA LIGASE); PROLYL-TRNA
SYNTHETASE (PROLINE--TRNA LIGASE)] >gi|68554|pir||SYHUQT
multifunctional aminoacyl-tRNA ligase - human
>gi|31958|emb|CAA38224.1| (X54326) glutaminyl-tRNA
synthetase [Homo sapiens]
Length = 1440
Score = 307 bits (777), Expect = 2e-82
Identities = 170/496 (34%), Positives = 285/496 (57%), Gaps = 29/496 (5%)
Query: 9 ENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPA 68
EN ++W+++VI ++ +++ + + G + P+ I + I+ F E+++ G + FP
Sbjct: 950 ENLADWYSQVITKSEMIEY-HDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPM 1008
Query: 69 LIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADL 128
+ ++ +KE H+A F EV W+T +G L + +RPTSET MY +A W++SH DL
Sbjct: 1009 FVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDL 1068
Query: 129 PFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKR 188
P K+ Q NV R+E KH +P +R RE + E H+A A E+A ++ + L+++ + +
Sbjct: 1069 PIKLNQWCNVVRWEFKHPQPFLRTREF-LWQEGHSAFATMEEAAEEVLQILDLYAQVYEE 1127
Query: 189 -LAIAYIISKRPEWDKFPGAFYSLGAEV-VMPDGRTLQIGTMHNYKQNFAKAYNILYE-- 244
LAI + ++ E +KF G Y+ E + GR +Q GT H+ QNF+K + I++E
Sbjct: 1128 LLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDP 1187
Query: 245 KEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIP-----KKEK 299
K G + +Q ++G++ R + + +HGD+ G+VLPP +A +QVVI+P +E
Sbjct: 1188 KIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEED 1247
Query: 300 QEIVYEYAREIEEELRTAGIRVHLDMREK-RPGWKFYDWELKGVPVRIEVGPRDVENSTV 358
+E + + L + IRV D+R+ PGWKF WELKGVP+R+EVGPRD+++
Sbjct: 1248 KEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQF 1307
Query: 359 VLARRDKLEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFED 418
V RRD EK+T+ E K++ + +DI L+ RA+E L +H+ T+E+ +K +
Sbjct: 1308 VAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDS 1367
Query: 419 RRGIVEIPWCGEESC------GLKMEEELD-------AKMLGIPYPEEKAKAPEGSRCPV 465
+ IV+IP+CGE C +++L+ AK L IP+ + + G++C V
Sbjct: 1368 GK-IVQIPFCGEIDCEDWIKKTTARDQDLEPGAPSMGAKSLCIPF-KPLCELQPGAKC-V 1424
Query: 466 CGRD-AKFIARFARTY 480
CG++ AK+ F R+Y
Sbjct: 1425 CGKNPAKYYTLFGRSY 1440
>gi|11426207 glutamyl-prolyl tRNA synthetase [Homo sapiens]
Length = 1440
Score = 307 bits (777), Expect = 2e-82
Identities = 170/496 (34%), Positives = 285/496 (57%), Gaps = 29/496 (5%)
Query: 9 ENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPA 68
EN ++W+++VI ++ +++ + + G + P+ I + I+ F E+++ G + FP
Sbjct: 950 ENLADWYSQVITKSEMIEY-HDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPM 1008
Query: 69 LIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADL 128
+ ++ +KE H+A F EV W+T +G L + +RPTSET MY +A W++SH DL
Sbjct: 1009 FVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDL 1068
Query: 129 PFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKR 188
P K+ Q NV R+E KH +P +R RE + E H+A A E+A ++ + L+++ + +
Sbjct: 1069 PIKLNQWCNVVRWEFKHPQPFLRTREF-LWQEGHSAFATMEEAAEEVLQILDLYAQVYEE 1127
Query: 189 -LAIAYIISKRPEWDKFPGAFYSLGAEV-VMPDGRTLQIGTMHNYKQNFAKAYNILYE-- 244
LAI + ++ E +KF G Y+ E + GR +Q GT H+ QNF+K + I++E
Sbjct: 1128 LLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDP 1187
Query: 245 KEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIP-----KKEK 299
K G + +Q ++G++ R + + +HGD+ G+VLPP +A +QVVI+P +E
Sbjct: 1188 KIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEED 1247
Query: 300 QEIVYEYAREIEEELRTAGIRVHLDMREK-RPGWKFYDWELKGVPVRIEVGPRDVENSTV 358
+E + + L + IRV D+R+ PGWKF WELKGVP+R+EVGPRD+++
Sbjct: 1248 KEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQF 1307
Query: 359 VLARRDKLEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFED 418
V RRD EK+T+ E K++ + +DI L+ RA+E L +H+ T+E+ +K +
Sbjct: 1308 VAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDS 1367
Query: 419 RRGIVEIPWCGEESC------GLKMEEELD-------AKMLGIPYPEEKAKAPEGSRCPV 465
+ IV+IP+CGE C +++L+ AK L IP+ + + G++C V
Sbjct: 1368 GK-IVQIPFCGEIDCEDWIKKTTARDQDLEPGAPSMGAKSLCIPF-KPLCELQPGAKC-V 1424
Query: 466 CGRD-AKFIARFARTY 480
CG++ AK+ F R+Y
Sbjct: 1425 CGKNPAKYYTLFGRSY 1440
>pir||T16915 hypothetical protein T20H4.3 - Caenorhabditis elegans
>gi|459009|gb|AAA50660.1| (U00037) similar to
multifunctional aminoacyl-tRNA synthetase, especially to
the prolyl-tRNA synthetase region [Caenorhabditis
elegans]
Length = 581
Score = 305 bits (772), Expect = 9e-82
Identities = 168/488 (34%), Positives = 275/488 (55%), Gaps = 19/488 (3%)
Query: 9 ENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPA 68
+N+SEW++EVI +A +++ Y V G V P+ + ++I+++ +++ G + FP
Sbjct: 97 DNYSEWYSEVITKAEMIEY-YDVSGCYVLRPWSFAVWESIQEWFDSGIKKLGVKNCYFPM 155
Query: 69 LIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADL 128
+ ++E HIA F EV W+T AG+ + + +RPTSET MY + W++SH DL
Sbjct: 156 FVSNAALEREKTHIADFAPEVAWVTRAGNSEMAEPIAIRPTSETVMYPSYKKWVQSHRDL 215
Query: 129 PFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNL-MK 187
P K+ Q NV R+E KH P +R RE + E HTA A+ DAE+++ + L+++ +
Sbjct: 216 PIKLNQWCNVVRWEFKHPTPFLRTREF-LWQEGHTAFANPADAEKEVFQILDLYAGVYTD 274
Query: 188 RLAIAYIISKRPEWDKFPGAFYSLGAEV-VMPDGRTLQIGTMHNYKQNFAKAYNILYE-- 244
LAI + ++ E +KF G ++ E V +GR +Q T H+ QNF+K ++I YE
Sbjct: 275 LLAIPVVKGRKSEKEKFAGGDFTTTVEAYVACNGRGIQGATSHHLGQNFSKMFDISYEDP 334
Query: 245 KEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIP-KKEKQEIV 303
++G + Q ++G+S R + A++ IHGDD+G+VLPP +A +QV++VP+ K E ++ +
Sbjct: 335 AKEGERAFAWQNSWGLSTRTIGAMVMIHGDDKGLVLPPRVAAVQVIVVPVGFKTENKQSL 394
Query: 304 YEYAREIEEELRTAGIRVHLDMREK-RPGWKFYDWELKGVPVRIEVGPRDVENSTVVLAR 362
++ ++ ++L G++ D+RE GWKF WELKGVP+R EVGP D+ + V
Sbjct: 395 FDAVDKVTKDLVADGVKAEHDLRENYNAGWKFNHWELKGVPIRFEVGPNDLAKNQVTAVI 454
Query: 363 RDKLEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFEDRRGI 422
R EK + E L V+ L D+I +Y + +SH+K +EE KK D + I
Sbjct: 455 RHNGEKKQLSLEGLSKTVKSLLDEIHTAMYNKVLAQRDSHLKSTTCIEEFKKLL-DEKCI 513
Query: 423 VEIPWCGEESCGLKMEE----------ELDAKMLGIPYPEEKAKAPEGSRCPVCGRDAKF 472
+ P+CG C ++++ ++ AK L IP + K + P P C +AK
Sbjct: 514 ILSPFCGRPDCEEEIKKASTREDGEGAQMGAKTLCIPLDQPKQELPSKCLFPSCTYNAKA 573
Query: 473 IARFARTY 480
A F R+Y
Sbjct: 574 FALFGRSY 581
>pir||A70150 proline--tRNA ligase (EC 6.1.1.15) proS - Lyme disease spirochete
>gi|2688299|gb|AAC66767.1| (AE001145) prolyl-tRNA
synthetase (proS) [Borrelia burgdorferi]
Length = 488
Score = 302 bits (765), Expect = 6e-81
Identities = 173/483 (35%), Positives = 279/483 (56%), Gaps = 15/483 (3%)
Query: 9 ENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPA 68
+++S+W+ +++++A + D PVKG V +PYG I I+ + ++ + TGH+ FP
Sbjct: 10 DDYSKWYLDIVQKAKLADYS-PVKGCMVIMPYGYSIWSKIQSILDKKFKETGHENAYFPM 68
Query: 69 LIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADL 128
LIP + ++E +HI GF E I AG E L L+LRPTSET +++M++ WI+S+ DL
Sbjct: 69 LIPYSFLEREKDHIDGFSPEFAIIKDAGGESLAEPLVLRPTSETIIWNMYSKWIKSYRDL 128
Query: 129 PFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMK- 187
P K+ Q NV R+E K TRP +R E + E HTAHA E+A + L+++ ++
Sbjct: 129 PLKINQWANVVRWE-KRTRPFLRTTEF-LWQEGHTAHATEEEALEETLLILDVYKRFIED 186
Query: 188 RLAIAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYNILYEKED 247
LAI K+ E +KF GA + E +M D + LQ T H NFAKA+++ ++ +D
Sbjct: 187 YLAIPVFCGKKSEKEKFAGAVSTYSIEALMQDKKALQAATSHYLGLNFAKAFDVKFQDKD 246
Query: 248 GTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQ--EIVYE 305
G +V +++G+S RL+ A+I +H D++G+VLPP IAPI+++++PI KKE + + + +
Sbjct: 247 GKMRHVFASSWGVSTRLIGALIMVHSDEKGLVLPPRIAPIEIIVIPIFKKEDEINKKILD 306
Query: 306 YAREIEEELRTAGIRVHLDMR-EKRPGWKFYDWELKGVPVRIEVGPRDVENSTVVLARRD 364
Y+ + + L+ A RV +D PG++F E KG+P+R+EVG DV ++V ++RRD
Sbjct: 307 YSDCVVDALKKAEFRVEIDKDVRSSPGFRFSSAEFKGIPIRLEVGINDVLLNSVTISRRD 366
Query: 365 KLEKI--TIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRV-----ETLEEAKKAFE 417
K K I + L+ KV+ D + K L++RA + + K + ++ E K
Sbjct: 367 KDRKFKYQISLDSLISKVKVELDLMQKDLFQRALNFRILNTKEIFRSSKDSYETFKAYVN 426
Query: 418 DRRGIVEIPWCGEESCGLKMEEELDAKMLGIPYPEEKAKAPEGSRCPVCGRDAKFIARFA 477
D G V WCG +C ++ E A + IP + KA+ G C C AK+ FA
Sbjct: 427 DYSGFVLSCWCGSLNCENIIKNETKATIRCIP-DDFKARDLTGMTCIYCSSKAKYFVLFA 485
Query: 478 RTY 480
++Y
Sbjct: 486 KSY 488
>gi|6321808 Aminoacyl tRNA-synthetase; Yhr020wp [Saccharomyces cerevisiae]
>gi|731640|sp|P38708|YHI0_YEAST PUTATIVE PROLYL-TRNA
SYNTHETASE YHR020W (PROLINE--TRNA LIGASE) (PRORS)
>gi|626755|pir||S46774 multifunctional amino acid--tRNA
ligase homolog - yeast (Saccharomyces cerevisiae)
>gi|500692|gb|AAB68873.1| (U10399) Yhr020wp
[Saccharomyces cerevisiae]
Length = 688
Score = 291 bits (736), Expect = 2e-77
Identities = 159/500 (31%), Positives = 277/500 (54%), Gaps = 34/500 (6%)
Query: 10 NFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPAL 69
+F W+ +++ + +LD Y V G + P I +NI+K+ ++++ G Q FP
Sbjct: 194 DFPGWYQQILTKGEMLDY-YDVSGCYILRPPSYAIWENIQKWFDDKIKAIGVQNAYFPMF 252
Query: 70 IPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLP 129
+ +KE +H+ GF EV W+T AG L+ + +RPTSET MY +A W++S+ DLP
Sbjct: 253 VSSRVLEKEKDHVEGFAPEVAWVTRAGSSELEEPIAIRPTSETVMYPYYAKWVQSYRDLP 312
Query: 130 FKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKR- 188
K+ Q +V R+E KH +P +R RE + E HTAH +DAE ++ + L+ + + +
Sbjct: 313 LKLNQWNSVVRWEFKHPQPFLRTREF-LWQEGHTAHLTAKDAEEEVLQILDFYAGVYEEL 371
Query: 189 LAIAYIISKRPEWDKFPGAFYSLGAEVVMPD-GRTLQIGTMHNYKQNFAKAYNILYEKED 247
LA+ + ++ E +KF G ++ E +P GR +Q T H+ QNF+K +N+ E
Sbjct: 372 LAVPVVKGRKTEKEKFAGGDFTTTCEGYIPQTGRGIQGATSHHLGQNFSKMFNLSVENPL 431
Query: 248 GTHD---YVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPI-----PKKEK 299
G+ + +Q ++G+S R++ ++ IH D++G+V+PP ++ Q V++P+ +E+
Sbjct: 432 GSDHPKIFAYQNSWGLSTRVIGVMVMIHSDNKGLVIPPRVSQFQSVVIPVGITKKTSEEQ 491
Query: 300 QEIVYEYAREIEEELRTAGIRVHLDMREK-RPGWKFYDWELKGVPVRIEVGPRDVENSTV 358
++ ++E AR +E L+ GIR D + PGWKF +ELKG+P+RIE+GP+D+E + V
Sbjct: 492 RKHIHETARSVESRLKKVGIRAFGDYNDNYTPGWKFSQYELKGIPIRIELGPKDIEKNQV 551
Query: 359 VLARRDKLEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFED 418
V+ RR+ +K + +EL ++ E+ +++ L+++A E ++H V A +
Sbjct: 552 VVVRRNDSKKYVVSFDELEARIPEILEEMQGDLFKKAKELFDTHRVIVNEWSGFVPAL-N 610
Query: 419 RRGIVEIPWCGEESC-------------GLKMEEE-----LDAKMLGIPYPEEKAKAPEG 460
++ ++ PWCG C G + EE+ + AK L IP+ ++ EG
Sbjct: 611 KKNVILAPWCGVMECEEDIKESSAKKDDGEEFEEDDKAPSMGAKSLCIPF--DQPVLNEG 668
Query: 461 SRCPVCGRDAKFIARFARTY 480
+C C R A F R+Y
Sbjct: 669 QKCIKCERIAVNYCMFGRSY 688
>gb|AAF56211.1| (AE003745) Aats-glupro gene product [Drosophila melanogaster]
Length = 1714
Score = 286 bits (725), Expect = 3e-76
Identities = 167/496 (33%), Positives = 273/496 (54%), Gaps = 28/496 (5%)
Query: 9 ENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPA 68
+N +W+++VI + +++ Y V G + + I K I+ + E+ R G +E FP
Sbjct: 1223 DNLPDWYSQVITKGEMIEY-YDVSGCYILRQWSFAIWKAIKTWFDAEITRMGVKECYFPI 1281
Query: 69 LIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADL 128
+ + +KE HIA F EV W+T +G L + +RPTSET MY +A W++S+ DL
Sbjct: 1282 FVSKAVLEKEKTHIADFAPEVAWVTKSGDSDLAEPIAVRPTSETVMYPAYAKWVQSYRDL 1341
Query: 129 PFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKR 188
P ++ Q NV R+E K P +R RE + E HTA AD E+A +++ + L+++ +
Sbjct: 1342 PIRLNQWNNVVRWEFKQPTPFLRTREF-LWQEGHTAFADKEEAAKEVLDILDLYALVYTH 1400
Query: 189 -LAIAYIISKRPEWDKFPGAFYSLGAEV-VMPDGRTLQIGTMHNYKQNFAKAYNILYE-K 245
LAI + ++ E +KF G Y+ E + GR +Q T H+ QNF+K + I+YE
Sbjct: 1401 LLAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSKMFEIVYEDP 1460
Query: 246 EDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPI-----PKKEKQ 300
E YV+Q ++G++ R + +I +H D++G+VLPP +A IQ ++VP K +++
Sbjct: 1461 ETQQKKYVYQNSWGITTRTIGVMIMVHADNQGLVLPPHVACIQAIVVPCGITVNTKDDER 1520
Query: 301 EIVYEYAREIEEELRTAGIRVHLDMREK-RPGWKFYDWELKGVPVRIEVGPRDVENSTVV 359
+ + + +E+ L G+R D R+ PGWKF WELKGVP+R+EVGP+D++ +V
Sbjct: 1521 AQLLDACKALEKRLVGGGVRCEGDYRDNYSPGWKFNHWELKGVPLRLEVGPKDLKAQQLV 1580
Query: 360 LARRDKLEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFEDR 419
RRD +EKITI ++ K+ L + I + + +A E + SH K+V + F ++
Sbjct: 1581 AVRRDTVEKITIPLADVEKKIPALLETIHESMLNKAQEDMTSHTKKVTNWTDF-CGFLEQ 1639
Query: 420 RGIVEIPWCGEESCGLKMEEE-------------LDAKMLGIPYPEEKAKAPEGSRC--P 464
+ I+ P+CGE SC K++ + + AK L IP+ ++ A +C P
Sbjct: 1640 KNILLAPFCGEISCEDKIKADSARGEEAEPGAPAMGAKSLCIPF-DQPAPIAASDKCINP 1698
Query: 465 VCGRDAKFIARFARTY 480
C KF F R+Y
Sbjct: 1699 SCTNKPKFYTLFGRSY 1714
>sp|P28668|SYEP_DROME MULTIFUNCTIONAL AMINOACYL-TRNA SYNTHETASE [INCLUDES: GLUTAMYL-TRNA
SYNTHETASE (GLUTAMATE--TRNA LIGASE); PROLYL-TRNA
SYNTHETASE (PROLINE--TRNA LIGASE)] >gi|103253|pir||S18644
multifunctional amino acid--tRNA ligase (EC 6.1.1.-) -
fruit fly (Drosophila melanogaster)
>gi|157564|gb|AAA28594.1| (M74104) transfer RNA-Glu-Pro
aminoacyl synthetase [Drosophila melanogaster]
>gi|1871360|gb|AAC47469.1| (U59923) glutamyl-prolyl-tRNA
synthetase [Drosophila melanogaster]
Length = 1714
Score = 286 bits (724), Expect = 4e-76
Identities = 167/497 (33%), Positives = 273/497 (54%), Gaps = 29/497 (5%)
Query: 9 ENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPA 68
+N +W+++VI + +++ Y V G + + I K I+ + E+ R G +E FP
Sbjct: 1222 DNLPDWYSQVITKGEMIEY-YDVSGCYILRQWSFAIWKAIKTWFDAEITRMGVKECYFPI 1280
Query: 69 LIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADL 128
+ + +KE HIA F EV W+T +G L + +RPTSET MY +A W++S+ DL
Sbjct: 1281 FVSKAVLEKEKTHIADFAPEVAWVTKSGDSDLAEPIAVRPTSETVMYPAYAKWVQSYRDL 1340
Query: 129 PFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKR 188
P ++ Q NV R+E K P +R RE + E HTA AD E+A +++ + L+++ +
Sbjct: 1341 PIRLNQWNNVVRWEFKQPTPFLRTREF-LWQEGHTAFADKEEAAKEVLDILDLYALVYTH 1399
Query: 189 -LAIAYIISKRPEWDKFPGAFYSLGAEV-VMPDGRTLQIGTMHNYKQNFAKAYNILYEKE 246
LAI + ++ E +KF G Y+ E + GR +Q T H+ QNF+K + I+YE
Sbjct: 1400 LLAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSKMFEIVYEDP 1459
Query: 247 DGTHD--YVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPI-----PKKEK 299
+ T YV+Q ++G++ R + +I +H D++G+VLPP +A IQ ++VP K ++
Sbjct: 1460 EKTQQKKYVYQNSWGITTRTIGVMIMVHADNQGLVLPPHVACIQAIVVPCGITVNTKDDE 1519
Query: 300 QEIVYEYAREIEEELRTAGIRVHLDMREK-RPGWKFYDWELKGVPVRIEVGPRDVENSTV 358
+ + + + +E+ L G+R D R+ PGWKF WELKGVP+R+EVGP+D++ +
Sbjct: 1520 RAQLLDACKALEKRLVGGGVRCEGDYRDNYSPGWKFNHWELKGVPLRLEVGPKDLKAQQL 1579
Query: 359 VLARRDKLEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFED 418
V RRD EKITI ++ K+ L + I + + +A E + SH K+V + F +
Sbjct: 1580 VAVRRDTGEKITIPLADVEKKIPALLETIHESMLNKAQEDMTSHTKKVTNWTDF-CGFLE 1638
Query: 419 RRGIVEIPWCGEESCGLKMEEE-------------LDAKMLGIPYPEEKAKAPEGSRC-- 463
++ I+ P+CGE SC K++ + + AK L IP+ ++ A +C
Sbjct: 1639 QKNILLAPFCGEISCEDKIKADSARGEEAEPGAPAMGAKSLCIPF-DQPAPIAASDKCIN 1697
Query: 464 PVCGRDAKFIARFARTY 480
P C KF F R+Y
Sbjct: 1698 PSCTNKPKFYTLFGRSY 1714
>pir||T39812 hypothetical protein SPBC19C7.06 - fission yeast
(Schizosaccharomyces pombe) >gi|3218410|emb|CAA19574.1|
(AL023859) putative prolyl-trna synthetase
[Schizosaccharomyces pombe]
Length = 716
Score = 275 bits (697), Expect = 6e-73
Identities = 166/510 (32%), Positives = 264/510 (51%), Gaps = 38/510 (7%)
Query: 6 RWSENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVL 65
R +F W+ +V+ ++ +++ Y + G + P+ I + I+ + +E+++ G +
Sbjct: 210 RKDADFPNWYQQVLTKSDMIEY-YDISGCYILKPWSYSIWEAIQGWFDKEIKKLGVRNGY 268
Query: 66 FPALIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSH 125
FP + +KE +H+ GF EV W+T AG LD + +RPTSET MY +A WIRSH
Sbjct: 269 FPLFVSSKVLEKEKDHVEGFAPEVAWVTRAGTSELDEPIAIRPTSETVMYPYYAKWIRSH 328
Query: 126 ADLPFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNL 185
DLP K+ Q +V R+E K+ +P +R RE + E HTAH E A ++ + L+++ +
Sbjct: 329 RDLPLKLNQWNSVVRWEFKNPQPFLRTREF-LWQEGHTAHMTLEGATEEVHQILDLYARI 387
Query: 186 -MKRLAIAYIISKRPEWDKFPGAFYSLGAEVVMP-DGRTLQIGTMHNYKQNFAKAYNILY 243
LA+ I + E +KF G ++ E +P GR +Q T H QNF+K +NI+
Sbjct: 388 YTDLLAVPVIKGVKSENEKFAGGMFTTTVEGYIPTTGRGIQGATSHCLGQNFSKMFNIVV 447
Query: 244 EKEDGTHD--------YVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVP-- 293
E + +V Q ++G+S R + + +HGDD+G+ LPP IA +Q V+VP
Sbjct: 448 EDPNAEIGPTGERPKLFVWQNSWGLSTRTIGVAVMVHGDDKGLKLPPAIALVQSVVVPCG 507
Query: 294 IPKK---EKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGP 350
I K +++ + + ++ + L A IR D+R PG+KF WE+KGVP+R+E GP
Sbjct: 508 ITNKTTDQERNEIEGFCSKLADRLNAADIRTEADLRAYTPGYKFSHWEMKGVPLRLEYGP 567
Query: 351 RDVENSTVVLARRDKLEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLE 410
D + + V RRD EKI + L V +L I +YE A ++H+ +V+
Sbjct: 568 NDAKKNQVTAVRRDTFEKIPVPLNNLEKGVSDLLAKIQTNMYETAKAERDAHVVKVKEWA 627
Query: 411 EAKKAFEDRRGIVEIPWCGEESC-------------GLKMEEE----LDAKMLGIPYPE- 452
+ A +++ IV IPWC C G + E+E + AK L IP +
Sbjct: 628 DFVPAL-NKKNIVMIPWCNTTECEKEIKKNSARQVNGDEPEDEKAPSMGAKSLCIPLEQP 686
Query: 453 --EKAKAPEGSRCPVCGRDAKFIARFARTY 480
E A ++C CG AK F R+Y
Sbjct: 687 SGEDAIIEGTTKCAGCGNLAKVWGLFGRSY 716
>pir||B82890 prolyl aminoacyl-tRNA synthetase UU452 [imported] - Ureaplasma
urealyticum >gi|6899444|gb|AAF30864.1|AE002141_10
(AE002141) prolyl aminoacyl-tRNA synthetase [Ureaplasma
urealyticum]
Length = 472
Score = 231 bits (583), Expect = 1e-59
Identities = 139/413 (33%), Positives = 226/413 (54%), Gaps = 7/413 (1%)
Query: 9 ENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPA 68
ENF++W+ ++ A ++ +KGM V+ P I + I+ I E ++ G + + P
Sbjct: 13 ENFADWYTSIVNNAKLIQYT-DIKGMMVFQPNAWAIWEAIKNQIDVEFKKHGVRNLAMPT 71
Query: 69 LIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADL 128
LIP +EF+KE +HI GF E+F + G + LD +RPTSE + F + S+ DL
Sbjct: 72 LIPLSEFQKEKDHIEGFAPELFMVNQIGDKKLDNSYAIRPTSEILFCNYFKNIVNSYNDL 131
Query: 129 PFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKR 188
P K Q +V R E K TRP +R E + E H A +A+ K L+++ + ++
Sbjct: 132 PIKNNQWCSVMRAE-KTTRPFLRNAEF-HWQELHAIFASENEADSFAKVILDVYTDFVQN 189
Query: 189 -LAIAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYNILYEKED 247
L I I + W++F GA + E +M DG+ LQ T H Q FAKAY+I ++ +D
Sbjct: 190 YLCIPVIKGLKTPWERFAGAQKTYTIEAMMQDGQALQSATSHYLGQFFAKAYDIKFQGQD 249
Query: 248 GTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQEIVYEYA 307
YVHQ + G+S R++ A+I +H DD+G++LPP IA Q+ I+ I + +++ + +
Sbjct: 250 NQMHYVHQMSAGLSTRIIGALIMVHADDQGLILPPDIAFNQIAILTIFSNKNPQLL-KIS 308
Query: 308 REIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVENSTVVLARRDKLE 367
++I E+L R+ D +K G+K E++G P+ I VG +++ N VV+ RRD E
Sbjct: 309 QQICEQLN--NYRLFEDHSDKGIGYKLAQQEIEGTPICILVGAKELVNQQVVIVRRDTHE 366
Query: 368 KITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFEDRR 420
KI + +L + +L DI + +YE+A + L I V +EE K+ +
Sbjct: 367 KINVDLTDLKLIIPKLLADIKRNIYEKAKKDLEDSIVFVNNIEELKQVIAQNK 419
>sp|P75382|SYP_MYCPN PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE) (PRORS)
>gi|2146518|pir||S73762 probable proline--tRNA ligase
(EC 6.1.1.15) - Mycoplasma pneumoniae (strain ATCC
29342) >gi|1674123|gb|AAB96084.1| (AE000043) putative
prolyl-tRNA synthetase; similar to Swiss-Prot Accession
Number P38708, from S. cerevisiae [Mycoplasma
pneumoniae]
Length = 483
Score = 161 bits (404), Expect = 1e-38
Identities = 127/497 (25%), Positives = 232/497 (46%), Gaps = 44/497 (8%)
Query: 9 ENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEK------------------ 50
+N + W+++++ +A ++ VKG N +LP + I++
Sbjct: 6 QNLTLWYDQLLSKAQLVSYG-DVKGTNCFLPNSWNLWLQIQRLYNNATALIKLKDKVILK 64
Query: 51 -FIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPT 109
FI E ++V P L +E++KE H+ GF E+F I G + L L+LRPT
Sbjct: 65 QFIPIEPLPYTVEQVQLPTLSFYSEYQKEKRHVEGFNPELFLIEQIGTKKLHDPLVLRPT 124
Query: 110 SETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFE 169
SE A +++ S+ +LP Q V+R E K+TRP +R E + E H +D
Sbjct: 125 SEIAFCNLWKKQSFSYQNLPVIYNQWTCVFRAE-KNTRPFLRNSEFY-WQETHGLFSDGV 182
Query: 170 DAERQIKEDLEIF-DNLMKRLAIAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTM 228
++E +++ D ++ +L I + + ++F GA + E +MPDG+ LQ T
Sbjct: 183 NSESAAIAFWKLYQDIIVNQLCIPAFVGLKSPNERFAGAQNTWTVESIMPDGQALQCATS 242
Query: 229 HNYKQNFAKAYNILYEKEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQ 288
H+ Q F K + + ++ + + + G+S R+L A++ H DD G+VLP +APIQ
Sbjct: 243 HDLGQTFTKPFGLTFQNQANQQAIPYSFSCGISTRILGALLLTHSDDFGLVLPWKVAPIQ 302
Query: 289 VVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEV 348
V + KK + V E A++++ L IR E + G + E+ G+P ++ V
Sbjct: 303 VKLYLFDKKGDTKTV-ELAQKVQTLLEQLAIRFQFIKVENQLGKQLGQGEVNGIPFQLIV 361
Query: 349 GPRDVENSTVVLARRDKLEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVET 408
TV + R K E+L + EL + +Y++A + + + T
Sbjct: 362 D----NPQTVNIFNRLTRVKTAYSFEQLASRFVELVQQYHQAMYDKAKAVVQQKVVQATT 417
Query: 409 LEEAKKAFEDRRGIVEIPWCGEESCGLKMEEELDAKM-----LGIPYPEEKAKAPEGSRC 463
L++ ++AF D++ ++ C +++ + L+ ++ + + E+ + P+ C
Sbjct: 418 LKQIEQAFNDKKAVL---------CAVRLTDTLEQQLKERYQVTVRCCLEQLQKPQ--IC 466
Query: 464 PVCGRDAKFIARFARTY 480
P G A+ AR Y
Sbjct: 467 PFSGESAQDYVLIARAY 483
>sp|P47525|SYP_MYCGE PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE) (PRORS)
>gi|1361767|pir||C64231 proline--tRNA ligase (EC
6.1.1.15) - Mycoplasma genitalium
>gi|1045979|gb|AAC71505.1| (U39708) prolyl-tRNA
synthetase (proS) [Mycoplasma genitalium]
Length = 483
Score = 150 bits (376), Expect = 3e-35
Identities = 109/381 (28%), Positives = 188/381 (48%), Gaps = 17/381 (4%)
Query: 63 EVLFPALIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWI 122
+V P L +E++KE HI GF E+F I G + L+ L+LRPTSE A +++
Sbjct: 78 QVQLPTLSFYSEYQKEKTHIKGFNPELFLINQVGQKQLNDPLVLRPTSEIAFCNLWKKQE 137
Query: 123 RSHADLPFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIF 182
S+ DLP Q V+R E K+TRP +R E + E H D +E+ ++
Sbjct: 138 LSYHDLPLIYNQWTQVFRAE-KNTRPFLRNSEFY-WQETHGLFVDQSQSEQAAISFWNLY 195
Query: 183 DNLM-KRLAIAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYNI 241
+L+ +L I + + E +KF GA + E +MPDG++LQ T H+ F K++ I
Sbjct: 196 QDLIINKLCIPAFVGLKSESEKFAGAKNTWTIEAIMPDGQSLQCATSHDLGDTFTKSFTI 255
Query: 242 LYEKEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQE 301
Y+ + + GMS R+L A+ H DD G+VLP +A QV + K +
Sbjct: 256 SYQSKTNQKMTPSSFSCGMSTRILGAIFLTHSDDYGLVLPWYLASKQVKLYLFDKNNNPK 315
Query: 302 IVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVENSTVVLA 361
A +++ L IR + G + E++G+P+++ V D E + +
Sbjct: 316 -TRALAFLVKDFLEKLKIRFSFIEINNQLGKQLLKGEIEGIPLQMIV---DNEKTINIFN 371
Query: 362 RRDKLEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFEDRRG 421
R +L K ++ L + L ++ +Y +AN+ + + RV+TL+E ++AF++++
Sbjct: 372 RLTRL-KTSLTFANLQTEFVNLVNNYHTEMYRKANDLVEQKLARVQTLKEIEQAFKNKKA 430
Query: 422 IVEIPWCGEESCGLKMEEELD 442
++ C +K+ EL+
Sbjct: 431 VL---------CTVKLTGELE 442
>pir||T50797 hypothetical protein T30N20_150 - Arabidopsis thaliana
>gi|8979722|emb|CAB96843.1| (AL365234) putative protein
[Arabidopsis thaliana]
Length = 309
Score = 128 bits (319), Expect = 1e-28
Identities = 81/260 (31%), Positives = 136/260 (52%), Gaps = 37/260 (14%)
Query: 252 YVHQTTFGMSERLLA---------------AVIAIHGDDRGMVLPPTIAPIQVVIVPIPK 296
Y + T G+ +RLL A HGDD+G+V PP +AP+QVV++ +P
Sbjct: 56 YTNTTLKGLLQRLLGLQELVDKRTQGPPFEAACMTHGDDKGLVFPPKVAPVQVVVIHVPI 115
Query: 297 K---EKQEIVYEYAREIEEELRTAGIRVHLDMREKRP-GWKFYDWELKGVPVRIEVGPRD 352
K + QE+ + +E L AGIR D+R+ GWK+ D EL GVP+RIE GPRD
Sbjct: 116 KGAADYQELC-DACEAVESTLLGAGIRAEADIRDNYSCGWKYADQELTGVPLRIETGPRD 174
Query: 353 VENSTVVLARRDKLEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEA 412
+ N V + RD K+ +KR +L+++V++L + I LY+ A + ++VET +E
Sbjct: 175 LANDQVRIVTRDNGAKMDVKRGDLIEQVKDLLEKIQSNLYDVAKRKVEECTQKVETWDEF 234
Query: 413 KKAFEDRRGIVEIPWCGEESCGLKMEEELDAKMLG------------IPYPEEKAKAPEG 460
+A ++ ++ PWC + +++E+++ + G + P E+ + E
Sbjct: 235 VEALSQKK-LILAPWCDK----VEVEKDVKRRTRGDETGGGGGGAKTLCTPLEQPELGEE 289
Query: 461 SRCPVCGRDAKFIARFARTY 480
+ C G+ AK + + R+Y
Sbjct: 290 TLCFASGKPAKKWSYWGRSY 309
>sp|O67583|SYT_AQUAE THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
>gi|7437523|pir||F70444 threonine--tRNA ligase (EC
6.1.1.3) - Aquifex aeolicus >gi|2984004|gb|AAC07549.1|
(AE000750) threonyl-tRNA synthetase [Aquifex aeolicus]
Length = 638
Score = 106 bits (261), Expect = 8e-22
Identities = 97/387 (25%), Positives = 178/387 (45%), Gaps = 54/387 (13%)
Query: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
G+ +WLP G K +E ++ EE + G+Q V P + +++ + + H+ ++ +F
Sbjct: 263 GLILWLPRGAIYRKVLEDYLREEHLKRGYQLVYTPH-VGKSKLWETSGHLECYKQNMFPS 321
Query: 93 THAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHT-RPLIR 151
E VK P + +++ RS+ +LP K++++ VYRYE L+R
Sbjct: 322 MKIDEEEYYVK----PMNCPFHIAIYKSRTRSYKELPLKLFELGTVYRYELSGVLHGLLR 377
Query: 152 VREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKRLA---IAYIISKRPEW------- 201
VR ++ +AH E I+E L+ + +K +S RPE+
Sbjct: 378 VRGFTQ-DDAHIVCTP-EQVNDVIRETLDFALSTLKDFGFNEFKIYLSTRPEYSIGSDEQ 435
Query: 202 ---------------------DKFPGAFYSLGAEVVMPD--GRTLQIGTMHNYKQNFAKA 238
D+ GAFY +V + D GR Q+ T+ + N +
Sbjct: 436 WEVSQNALKKAIEDLGYEYEIDEGGGAFYGPKIDVKIRDAIGRMWQLSTI-QFDFNLPER 494
Query: 239 YNILYEKEDGTHD---YVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIP 295
+++ Y D +H+ G ER ++ + +LP ++P QV+I+PI
Sbjct: 495 FDMTYVGPDNKKHRPYMIHRALLGSIERFTGILLEHYAG----LLPIWLSPTQVMIIPIA 550
Query: 296 KKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVEN 355
+ +EYA+++ E L+ GIR +D+RE+R K D ELK +PV + VG R+ +N
Sbjct: 551 DRH-----HEYAKKVYEFLKENGIRAEMDLREERMNAKIRDAELKKIPVILVVGDREAQN 605
Query: 356 STVVLARRDKLEKITIKREELVDKVRE 382
+TV + + + +++ + +D ++E
Sbjct: 606 NTVSVRTKKEGNLGSMELNKFLDWIKE 632
>sp|P56881|SYT_THETH THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
>gi|6689424|emb|CAB65483.1| (AJ250953) threonyl-tRNA
synthetase [Thermus thermophilus]
Length = 659
Score = 102 bits (252), Expect = 9e-21
Identities = 105/377 (27%), Positives = 159/377 (41%), Gaps = 59/377 (15%)
Query: 32 KGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFW 91
KG+ +WLP G + + + F+ EE R G+Q V P I E K + H + F
Sbjct: 271 KGLVLWLPKGNVVREELMAFMREEQVRRGYQLVTTPH-IGSLELYKTSGHYPYYAESQFP 329
Query: 92 ITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETK-HTRPLI 150
+ + +L+P + ++A RS+ +LP ++ + VYRYE L
Sbjct: 330 PISFKERGEEEEYLLKPMNCPHHIRIYAYRKRSYRELPLRLAEFGTVYRYEKAGELLGLT 389
Query: 151 RVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKRLAI-------AYIISKRPEWDK 203
RVR F AH F E E L + D ++K A A I + P+ DK
Sbjct: 390 RVRG----FTQDDAHI-FCTPEEVKGEFLGVLDLVLKVFATLGLKDYRARIGVRDPKSDK 444
Query: 204 FPG------------------------------AFYSLGAEVVMPD--GRTLQIGTMHNY 231
+ G AFY + V+ D GR Q+GT+
Sbjct: 445 YVGDEAKWALAERQIEEAAAEAGLRYTVEEGDAAFYGPKLDFVVKDALGREWQLGTIQ-V 503
Query: 232 KQNFAKAYNILYEKEDGTHD---YVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQ 288
N + + + Y +DG +H+ FG ER + +I D P +AP+Q
Sbjct: 504 DYNLPERFGLTYVGKDGEEHRPVMLHRAPFGSLERFIGILIEHFAGD----FPLWLAPVQ 559
Query: 289 VVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEV 348
V+VP+ EKQE +YARE+ L+ AG+R D R +R + D E++ VP + V
Sbjct: 560 AVVVPV--SEKQE---DYAREVAGRLKEAGLRAEADTRPERMQARIRDAEVQKVPYILVV 614
Query: 349 GPRDVENSTVVLARRDK 365
G R+ V + RR K
Sbjct: 615 GEREKAEGAVSVRRRKK 631
>pir||B75317 threonyl-tRNA synthetase - Deinococcus radiodurans (strain R1)
>gi|6459875|gb|AAF11630.1|AE002044_3 (AE002044)
threonyl-tRNA synthetase [Deinococcus radiodurans]
Length = 649
Score = 96.0 bits (235), Expect = 9e-19
Identities = 102/394 (25%), Positives = 169/394 (42%), Gaps = 60/394 (15%)
Query: 32 KGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFW 91
KG+ +WLP G + + + F+ E+ + G+Q V+ P I + + + H + F
Sbjct: 267 KGLPLWLPNGTVLREELTNFMKEQQFQRGYQGVVTPN-IGNLDLYRTSGHYPYYSESQFN 325
Query: 92 ITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETK-HTRPLI 150
E + +L+P + ++A RS+ DLP ++ + VYRYE L
Sbjct: 326 PIQVDEE----EYMLKPMNCPHHVRIYASKPRSYRDLPVRLAEFGTVYRYEQSGELNGLT 381
Query: 151 RVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKRLA---IAYIISKR-PEWDKFPG 206
RVR ++ +AH + +R+ + L++ ++K + + + R PE DK+ G
Sbjct: 382 RVRGFTQD-DAHIFCRP-DQLKREFLDVLDLTVLVLKTFGMTDVRFRVGVRDPESDKYVG 439
Query: 207 ------------------------------AFYSLGAEVVMPD--GRTLQIGTMHNYKQN 234
AFY + V+ D GR Q+GT+ N
Sbjct: 440 DEQNWALAERQIIEAVEEVGLPYTIEPGDAAFYGPKLDFVVKDVLGREWQLGTIQ-VDYN 498
Query: 235 FAKAYNILYEKEDGTHD---YVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVI 291
+ ++I Y EDG +H+ FG ER +I + D P +AP QV+I
Sbjct: 499 LPERFDISYTGEDGQEHRPIMIHRAPFGSIERFTGILIEHYAGD----FPLWLAPRQVMI 554
Query: 292 VPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPR 351
+PI + YA E+ EEL AG+R +D R K D EL +PV + VG +
Sbjct: 555 IPIADRHNA-----YAEELREELHRAGLRAEVDDSSNRMQAKVRDAELHKIPVMLIVGDK 609
Query: 352 DVENSTVVLARR---DKLEKITIKREELVDKVRE 382
+ E V + R E+ +K +EL ++ E
Sbjct: 610 EQEAREVSVRERTGEGTKERKGVKFDELKAELLE 643
>gb|AAF68032.1|AF252642_1 (AF252642) glu-prolyl-tRNA aminoacyl synthetase [Drosophila
simulans]
Length = 449
Score = 91.3 bits (223), Expect = 2e-17
Identities = 45/130 (34%), Positives = 73/130 (55%), Gaps = 1/130 (0%)
Query: 9 ENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPA 68
+N +W+++VI + +++ Y V G + + I K I+ + E+ R G +E FP
Sbjct: 320 DNLPDWYSQVITKGEMIEY-YDVSGCYILRHWSFAIWKAIKTWFDAEITRMGVKECYFPI 378
Query: 69 LIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADL 128
+ + +KE HIA F EV W+T +G L + +RPTSET MY +A W++S+ DL
Sbjct: 379 FVSKAVLEKEKTHIADFAPEVAWVTKSGDSDLAEPIAVRPTSETVMYPAYAKWVQSYRDL 438
Query: 129 PFKVYQIVNV 138
P ++ Q NV
Sbjct: 439 PIRLNQWNNV 448
>gb|AAF68027.1|AF252637_1 (AF252637) glu-prolyl-tRNA aminoacyl synthetase [Drosophila
simulans] >gi|7715425|gb|AAF68028.1|AF252638_1
(AF252638) glu-prolyl-tRNA aminoacyl synthetase
[Drosophila simulans]
>gi|7715427|gb|AAF68029.1|AF252639_1 (AF252639)
glu-prolyl-tRNA aminoacyl synthetase [Drosophila
simulans]
Length = 449
Score = 91.3 bits (223), Expect = 2e-17
Identities = 45/130 (34%), Positives = 73/130 (55%), Gaps = 1/130 (0%)
Query: 9 ENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPA 68
+N +W+++VI + +++ Y V G + + I K I+ + E+ R G +E FP
Sbjct: 320 DNLPDWYSQVITKGEMIEY-YDVSGCYILRHWSFAIWKAIKTWFDAEITRMGVKECYFPI 378
Query: 69 LIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADL 128
+ + +KE HIA F EV W+T +G L + +RPTSET MY +A W++S+ DL
Sbjct: 379 FVSKAVLEKEKTHIADFAPEVAWVTKSGDSDLAEPIAVRPTSETVMYPAYAKWVQSYRDL 438
Query: 129 PFKVYQIVNV 138
P ++ Q NV
Sbjct: 439 PIRLNQWNNV 448
>gb|AAF68030.1|AF252640_1 (AF252640) glu-prolyl-tRNA aminoacyl synthetase [Drosophila
simulans]
Length = 449
Score = 91.3 bits (223), Expect = 2e-17
Identities = 45/130 (34%), Positives = 73/130 (55%), Gaps = 1/130 (0%)
Query: 9 ENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPA 68
+N +W+++VI + +++ Y V G + + I K I+ + E+ R G +E FP
Sbjct: 320 DNLPDWYSQVITKGEMIEY-YDVSGCYILRHWSFAIWKAIKTWFDAEITRMGVKECYFPI 378
Query: 69 LIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADL 128
+ + +KE HIA F EV W+T +G L + +RPTSET MY +A W++S+ DL
Sbjct: 379 FVSKAVLEKEKTHIADFAPEVAWVTKSGDSDLAEPIAVRPTSETVMYPAYAKWVQSYRDL 438
Query: 129 PFKVYQIVNV 138
P ++ Q NV
Sbjct: 439 PIRLNQWNNV 448
>gb|AAF68031.1|AF252641_1 (AF252641) glu-prolyl-tRNA aminoacyl synthetase [Drosophila
simulans]
Length = 449
Score = 91.3 bits (223), Expect = 2e-17
Identities = 45/130 (34%), Positives = 73/130 (55%), Gaps = 1/130 (0%)
Query: 9 ENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPA 68
+N +W+++VI + +++ Y V G + + I K I+ + E+ R G +E FP
Sbjct: 320 DNLPDWYSQVITKGEMIEY-YDVSGCYILRHWSFAIWKAIKTWFDAEITRMGVKECYFPI 378
Query: 69 LIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADL 128
+ + +KE HIA F EV W+T +G L + +RPTSET MY +A W++S+ DL
Sbjct: 379 FVSKAVLEKEKTHIADFAPEVAWVTKSGDSDLAEPIAVRPTSETVMYPAYAKWVQSYRDL 438
Query: 129 PFKVYQIVNV 138
P ++ Q NV
Sbjct: 439 PIRLNQWNNV 448
>emb|CAA39134.1| (X55518) ProRS [Escherichia coli] >gi|147362|gb|AAA24420.1|
(M97858) prolyl-tRNA synthetase [Escherichia coli]
Length = 572
Score = 89.7 bits (219), Expect = 7e-17
Identities = 58/169 (34%), Positives = 90/169 (52%), Gaps = 9/169 (5%)
Query: 218 PDG-------RTLQIGTMHNYKQNFAKAYNILYEKEDGTHDYVHQTTFGMS-ERLLAAVI 269
PDG R +++G + +++A + EDG + + +G+ R++AA I
Sbjct: 397 PDGQGRLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAI 456
Query: 270 AIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKR 329
+ D+RG+V P IAP QV I+P+ K V E A ++ ELR GI V LD R++R
Sbjct: 457 EQNYDERGIVWPDAIAPFQVAILPM-NMHKSFRVQELAEKLYSELRAQGIEVLLDDRKER 515
Query: 330 PGWKFYDWELKGVPVRIEVGPRDVENSTVVLARRDKLEKITIKREELVD 378
PG F D EL G+P I +G R+++N + R EK IK ++V+
Sbjct: 516 PGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVE 564
>sp|P16659|SYP_ECOLI PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE) (PRORS) (GLOBAL RNA
SYNTHESIS FACTOR) >gi|4902936|dbj|BAA77870.1| (D83536)
Prolyl-tRNA synthetase (EC 6.1.1.15) [Escherichia coli]
Length = 572
Score = 89.7 bits (219), Expect = 7e-17
Identities = 58/169 (34%), Positives = 90/169 (52%), Gaps = 9/169 (5%)
Query: 218 PDG-------RTLQIGTMHNYKQNFAKAYNILYEKEDGTHDYVHQTTFGMS-ERLLAAVI 269
PDG R +++G + +++A + EDG + + +G+ R++AA I
Sbjct: 397 PDGQGRLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAI 456
Query: 270 AIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKR 329
+ D+RG+V P IAP QV I+P+ K V E A ++ ELR GI V LD R++R
Sbjct: 457 EQNYDERGIVWPDAIAPFQVAILPM-NMHKSFRVQELAEKLYSELRAQGIEVLLDDRKER 515
Query: 330 PGWKFYDWELKGVPVRIEVGPRDVENSTVVLARRDKLEKITIKREELVD 378
PG F D EL G+P I +G R+++N + R EK IK ++V+
Sbjct: 516 PGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVE 564
>pir||YPEC proline--tRNA ligase (EC 6.1.1.15) - Escherichia coli
>gi|1552770|gb|AAB08622.1| (U70214) proline-tRNA ligase
[Escherichia coli] >gi|1786392|gb|AAC73305.1| (AE000128)
proline tRNA synthetase [Escherichia coli K12]
Length = 572
Score = 89.7 bits (219), Expect = 7e-17
Identities = 58/169 (34%), Positives = 90/169 (52%), Gaps = 9/169 (5%)
Query: 218 PDG-------RTLQIGTMHNYKQNFAKAYNILYEKEDGTHDYVHQTTFGMS-ERLLAAVI 269
PDG R +++G + +++A + EDG + + +G+ R++AA I
Sbjct: 397 PDGQGRLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAI 456
Query: 270 AIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKR 329
+ D+RG+V P IAP QV I+P+ K V E A ++ ELR GI V LD R++R
Sbjct: 457 EQNYDERGIVWPDAIAPFQVAILPM-NMHKSFRVQELAEKLYSELRAQGIEVLLDDRKER 515
Query: 330 PGWKFYDWELKGVPVRIEVGPRDVENSTVVLARRDKLEKITIKREELVD 378
PG F D EL G+P I +G R+++N + R EK IK ++V+
Sbjct: 516 PGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVE 564
>pir||D82770 threonyl-tRNA synthetase XF0736 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9105624|gb|AAF83546.1|AE003915_11
(AE003915) threonyl-tRNA synthetase [Xylella fastidiosa]
Length = 635
Score = 89.3 bits (218), Expect = 9e-17
Identities = 94/362 (25%), Positives = 157/362 (42%), Gaps = 49/362 (13%)
Query: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
G+ W P G I + IE +I +G+ E+ P ++ + ++K H ++ +F+
Sbjct: 263 GLVFWHPKGWVIWQTIENYIRRVYRNSGYGELRCPQILDVSLWQKSG-HWDNYKENMFF- 320
Query: 93 THAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHT-RPLIR 151
T + VK P + +F + S+ DLP + + +R E L+R
Sbjct: 321 TDSEKRTYAVK----PMNCPGHVQVFNQGLHSYRDLPIRYGEFGACHRNEPSGALHGLLR 376
Query: 152 VR------------------EISRFF-EAHTAHADFEDAERQIK----EDLEIFDNLMKR 188
VR E++ F +A +ADF + QIK D + D+L
Sbjct: 377 VRGFTQDDGHIFCTEAQIESEVTAFHRQALQVYADFGFEDIQIKIALRPDKRLGDSLSWD 436
Query: 189 LAIAYIISK----RPEWDKFPG--AFYSLGAEVVMPD--GRTLQIGTMH-NYKQNFAKAY 239
A A + + EW + PG AFY E + D GRT Q+GT+ ++
Sbjct: 437 KAEAALRAALSACEVEWQELPGEGAFYGPKIEYHLKDAIGRTWQLGTIQVDFMMPGRLGA 496
Query: 240 NILYEKEDGTHDYV-HQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKE 298
+ E+ H + H+ G ER + +I + + P +AP+QVV+ I +
Sbjct: 497 EYVDERSQRCHPVMLHRAIVGSMERFIGILIEHYAG----IWPTWLAPVQVVVANITDAQ 552
Query: 299 KQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVENSTV 358
YEYA + + L G RV+ D+R ++ G+K + L+ VP + VG R+ EN TV
Sbjct: 553 -----YEYAERVHKALLNQGFRVNTDLRNEKIGYKIREHTLQRVPYLLVVGDREKENGTV 607
Query: 359 VL 360
+
Sbjct: 608 AV 609
>pir||S77857 probable proline--tRNA ligase (EC 6.1.1.15) - Mycoplasma capricolum
(fragment) >gi|530495|emb|CAA83845.1| (Z33341) Pro-tRNA
synthetase [Mycoplasma capricolum]
Length = 110
Score = 88.5 bits (216), Expect = 1e-16
Identities = 44/109 (40%), Positives = 63/109 (57%)
Query: 29 YPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGE 88
+ VKG ++ PYG +I + I+K++ EE ++ V FP LIPE+ F KE +HI GF E
Sbjct: 2 WSVKGTMIFRPYGYRIWELIQKYLDEEFKKVNVDNVYFPLLIPESLFNKEKDHIDGFSPE 61
Query: 89 VFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVN 137
+ +T G + L+ L +RPTSE M F+ I S+ DLP Q N
Sbjct: 62 IATVTRVGQKQLEENLFIRPTSEVLMMDYFSNEINSYRDLPLIYNQWCN 110
>pir||B81939 probable threonine--tRNA ligase (EC 6.1.1.3) NMA0929 [imported] -
Neisseria meningitidis (group A strain Z2491)
>gi|7379634|emb|CAB84201.1| (AL162754) putative
threonyl-tRNA synthetase [Neisseria meningitidis Z2491]
Length = 637
Score = 88.5 bits (216), Expect = 1e-16
Identities = 93/374 (24%), Positives = 161/374 (42%), Gaps = 67/374 (17%)
Query: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
GM W P G + + IE+ + +E+ G++EV P ++ +T ++K H ++ +F
Sbjct: 261 GMVFWHPKGWALWQVIEQHMRKELNAAGYKEVKTPQIMDKTFWEKSG-HWENYKDNMFVT 319
Query: 93 THAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHT-RPLIR 151
+ E ++P + +F +RS+ DLP ++ + + +R E L+R
Sbjct: 320 SSEKRE-----YAVKPMNCPGHVQIFNNGLRSYRDLPMRLAEFGSCHRNEPSGALHGLMR 374
Query: 152 VREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKRL-------AIAYIISKRPE---- 200
VR F AH E QI + F+ L+ R+ ++ +S RPE
Sbjct: 375 VRG----FVQDDAH--IFCTEDQIVSEARAFNELLVRIYKQFGFHDVSVKLSLRPEQRAG 428
Query: 201 ----WDKF--------------------PGAFYSLGAEVVMPD--GRTLQIGTMHNYKQN 234
WDK GAFY E + D GR+ Q GT+ + +
Sbjct: 429 SDDVWDKAEQGLREALTACGVEWGELPGEGAFYGPKIEYHVRDALGRSWQCGTL---QLD 485
Query: 235 FAKAYNILYEKEDGTHD-----YVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQV 289
F + E +D +H+ G ER + +I H P +AP+Q+
Sbjct: 486 FVLPERLDAEYVTENNDRARPVMLHRAILGSLERFIGILIENHAGS----FPLWLAPVQL 541
Query: 290 VIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVG 349
VI+ I + + +Y RE+ +L+ AG RV LD+R ++ G+K D P +I VG
Sbjct: 542 VIMNITENQA-----DYCREVAAKLQAAGFRVELDLRNEKIGYKIRDNSQYRFPYQIVVG 596
Query: 350 PRDVENSTVVLARR 363
++ + + V + R+
Sbjct: 597 DKEKQENKVAVRRK 610
>prf||1614347A Pro-tRNA synthetase [Escherichia coli]
Length = 572
Score = 87.8 bits (214), Expect = 3e-16
Identities = 58/169 (34%), Positives = 89/169 (52%), Gaps = 9/169 (5%)
Query: 218 PDG-------RTLQIGTMHNYKQNFAKAYNILYEKEDGTHDYVHQTTFGMS-ERLLAAVI 269
PDG R +++G + +++A + EDG + + G+ R++AA I
Sbjct: 397 PDGQGRLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCTGIGVTRVVAAAI 456
Query: 270 AIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKR 329
+ D+RG+V P IAP QV I+P+ K V E A ++ ELR GI V LD R++R
Sbjct: 457 EQNYDERGIVWPDAIAPFQVAILPM-NMHKSFRVQELAEKLYSELRAQGIEVLLDDRKER 515
Query: 330 PGWKFYDWELKGVPVRIEVGPRDVENSTVVLARRDKLEKITIKREELVD 378
PG F D EL G+P I +G R+++N + R EK IK ++V+
Sbjct: 516 PGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVE 564
>pir||E81167 threonyl-tRNA synthetase NMB0720 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7225946|gb|AAF41133.1| (AE002426) threonyl-tRNA
synthetase [Neisseria meningitidis MC58]
Length = 637
Score = 86.6 bits (211), Expect = 6e-16
Identities = 92/374 (24%), Positives = 160/374 (42%), Gaps = 67/374 (17%)
Query: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
GM W P G + + IE+ + +E+ G++EV P ++ +T ++K H ++ +F
Sbjct: 261 GMVFWHPKGWALWQVIEQHMRKELNAAGYKEVKTPQIMDKTFWEKSG-HWDNYKDNMFVT 319
Query: 93 THAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHT-RPLIR 151
+ E ++P + +F +RS+ DLP ++ + + +R E L+R
Sbjct: 320 SSEKRE-----YAVKPMNCPGHVQIFNNGLRSYRDLPMRLAEFGSCHRNEPSGALHGLMR 374
Query: 152 VREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKRL-------AIAYIISKRPE---- 200
VR F AH E QI + F+ L+ R+ ++ +S RPE
Sbjct: 375 VRG----FVQDDAH--IFCTEDQIVSEARAFNELLIRIYKQFGFHDVSVKLSLRPEKRAG 428
Query: 201 ----WDKF--------------------PGAFYSLGAEVVMPD--GRTLQIGTMHNYKQN 234
WDK GAFY E + D GR+ Q GT+ + +
Sbjct: 429 SDDVWDKAEQGLREALTACGVEWGELPGEGAFYGPKIEYHVRDALGRSWQCGTL---QLD 485
Query: 235 FAKAYNILYEKEDGTHD-----YVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQV 289
F + E +D +H+ G ER + +I H P +AP+Q+
Sbjct: 486 FVLPERLNAEYVTENNDRARPVMLHRAILGSLERFIGILIENHAGS----FPLWLAPVQL 541
Query: 290 VIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVG 349
VI+ I + + +Y RE+ +L+ AG R LD+R ++ G+K D P +I VG
Sbjct: 542 VIMNITENQA-----DYCREVAAKLQAAGFRAELDLRNEKIGYKIRDNSQYRFPYQIVVG 596
Query: 350 PRDVENSTVVLARR 363
++ + + V + R+
Sbjct: 597 DKEKQENKVAVRRK 610
>sp|P43830|SYP_HAEIN PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE) (PRORS)
>gi|1075176|pir||C64089 proline--tRNA ligase (EC
6.1.1.15) - Haemophilus influenzae (strain Rd KW20)
>gi|1573733|gb|AAC22388.1| (U32756) prolyl-tRNA
synthetase (proS) [Haemophilus influenzae Rd]
Length = 572
Score = 85.0 bits (207), Expect = 2e-15
Identities = 54/174 (31%), Positives = 92/174 (52%), Gaps = 10/174 (5%)
Query: 218 PDG-------RTLQIGTMHNYKQNFAKAYNILYEKEDGTHDYVHQTTFGMS-ERLLAAVI 269
PDG R +++G + + +++A + EDG + +G+ R++A+ I
Sbjct: 395 PDGKGTLQIKRGIEVGHIFQLGKKYSEAMKATVQGEDGKPLVMTMGCYGIGVTRVVASAI 454
Query: 270 AIHGDDRGMVLP-PTIAPIQVVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREK 328
H D+RG++ P IAP V IVP+ K E V +YA E+ L++ G+ V D R++
Sbjct: 455 EQHHDERGIIWPSDEIAPFTVAIVPM-NMHKSEAVQKYAEELYRTLQSQGVDVIFDDRKE 513
Query: 329 RPGWKFYDWELKGVPVRIEVGPRDVENSTVVLARRDKLEKITIKREELVDKVRE 382
RPG F D EL GVP + +G ++++N + R EK I +++L+ + E
Sbjct: 514 RPGVMFADMELIGVPHMVVIGEKNLDNGEIEYKNRRTGEKEMISKDKLLSVLNE 567
>sp|O51662|SYT_BORBU THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
>gi|7437524|pir||G70189 threonine--tRNA ligase (EC
6.1.1.3) thrZ - Lyme disease spirochete
>gi|2688663|gb|AAC67076.1| (AE001172) threonyl-tRNA
synthetase (thrZ) [Borrelia burgdorferi]
Length = 581
Score = 85.0 bits (207), Expect = 2e-15
Identities = 84/387 (21%), Positives = 160/387 (40%), Gaps = 68/387 (17%)
Query: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
G+ + P G KI IE F EE + G+ ++LF I ++ + + H+ ++ +F
Sbjct: 205 GLVFFHPNGAKIRALIEDFWREEHSKNGY-DILFTPHIGKSWLWQTSGHLDFYKDSMF-- 261
Query: 93 THAGHEPLDVK---LILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYET------ 143
E +++ L+P + +++ S+ DLPF+ ++ VYRYE
Sbjct: 262 -----EKIEMDKSDYYLKPMNCPFHIAIYNTGKHSYRDLPFRWAELGTVYRYEKIGALHG 316
Query: 144 ----------------KHTRPLIRVREISRFFEAHTAHADFEDAERQIKE---------- 177
H++ L ++E+ RF + F + + +
Sbjct: 317 MMRARGFTQDDAHIICTHSQVLDEIKEVLRFAIYMWSKFGFSNPKAYLSTKPDKSVGNDS 376
Query: 178 ----DLEIFDNLMKRLAIAYIISKRPEWDKFPGAFYSLGAEVVMPDG--RTLQIGTMHNY 231
L++ + + + Y E DK GAFY ++ + D R Q+ T+ +
Sbjct: 377 DWEMSLKVLEETLSDFEVPY------EIDKGGGAFYGPKIDLKIVDSLEREWQMSTIQ-F 429
Query: 232 KQNFAKAYNILYEKEDGTHD---YVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQ 288
N + +N+ Y EDG +H+ G ER ++ +G P ++P+Q
Sbjct: 430 DFNLPERFNMTYTAEDGKEKRPFMIHRALLGSIERFFGILVEHYGG----AFPLWLSPVQ 485
Query: 289 VVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEV 348
VVI+P+ IV +YA ++ + + GIR+ LD R K +++ K +P +
Sbjct: 486 VVIIPV-----NNIVEDYAIKVFNKFKNEGIRIKLDNSSSRMNAKIREYQAKKIPYMFII 540
Query: 349 GPRDVENSTVVLARRDKLEKITIKREE 375
G R+ + + R + +K +E
Sbjct: 541 GEREATEERISIRTRTNEQINGMKLDE 567
>sp|P18256|SYT2_BACSU THREONYL-TRNA SYNTHETASE 2 (THREONINE--TRNA LIGASE) (THRRS)
>gi|68515|pir||YSBST2 threonine--tRNA ligase (EC
6.1.1.3) thrZ [validated] - Bacillus subtilis
>gi|143764|gb|AAA22863.1| (M36593) threonyl-tRNA
synthetase (thrS2) (EC 6.1.1.3) [Bacillus subtilis]
>gi|2636292|emb|CAB15783.1| (Z99123) threonyl-tRNA
synthetase [Bacillus subtilis]
Length = 638
Score = 83.5 bits (203), Expect = 5e-15
Identities = 84/367 (22%), Positives = 159/367 (42%), Gaps = 56/367 (15%)
Query: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
GM +LP G + +E+F E G+ EV P ++ + +++ H + +++
Sbjct: 264 GMPFYLPKGQIVRNELERFSRELQTNAGYDEVRTPFMMNQRLWEQSG-HWDHYRDNMYF- 321
Query: 93 THAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHT-RPLIR 151
E D + ++P + +F + S+ DLP ++ + V+R+E ++R
Sbjct: 322 ----SEVDDTRFAMKPMNCPGHMLIFKNSLYSYRDLPIRMAEFGQVHRHEYSGALNGMLR 377
Query: 152 VREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKRLAIAYII--SKRPE--------W 201
VR + +AH + + E +IKE + + D + + Y + S RPE W
Sbjct: 378 VRTFCQD-DAHIFVRE-DQIESEIKEAIRLIDEVYRTFGFEYSVELSTRPEDSLGDDSLW 435
Query: 202 D--------------------KFPGAFYSLGAEVVMPDG--RTLQIGTMH---NYKQNFA 236
+ + GAFY + + D R+ Q T+ + F
Sbjct: 436 EASERALARVLEELGLSYEINEGDGAFYGPKIDFHIKDALKRSHQCATIQLDFQMPEKFD 495
Query: 237 KAY-NILYEKEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIP 295
Y N L EK +H+ FG +R +I +G P +APIQV I+P+
Sbjct: 496 LTYINELNEKVRPV--VIHRAVFGSIDRFFGILIEHYGG----AFPVWLAPIQVQIIPV- 548
Query: 296 KKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVEN 355
+ +Y R+++ EL+ AGIR +D R ++ G+K + +++ +P + +G + +
Sbjct: 549 ----SHVHLDYCRKVQAELKQAGIRAGIDERNEKLGYKIRESQVQKIPYVLVLGDHEEQE 604
Query: 356 STVVLAR 362
+ V + R
Sbjct: 605 NAVNVRR 611
>emb|CAB02510.1| (Z80360) Threonyl tRNA Synthetase [Bacillus subtilis]
Length = 601
Score = 83.5 bits (203), Expect = 5e-15
Identities = 84/367 (22%), Positives = 159/367 (42%), Gaps = 56/367 (15%)
Query: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
GM +LP G + +E+F E G+ EV P ++ + +++ H + +++
Sbjct: 227 GMPFYLPKGQIVRNELERFSRELQTNAGYDEVRTPFMMNQRLWEQSG-HWDHYRDNMYF- 284
Query: 93 THAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHT-RPLIR 151
E D + ++P + +F + S+ DLP ++ + V+R+E ++R
Sbjct: 285 ----SEVDDTRFAMKPMNCPGHMLIFKNSLYSYRDLPIRMAEFGQVHRHEYSGALNGMLR 340
Query: 152 VREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKRLAIAYII--SKRPE--------W 201
VR + +AH + + E +IKE + + D + + Y + S RPE W
Sbjct: 341 VRTFCQD-DAHIFVRE-DQIESEIKEAIRLIDEVYRTFGFEYSVELSTRPEDSLGDDSLW 398
Query: 202 D--------------------KFPGAFYSLGAEVVMPDG--RTLQIGTMH---NYKQNFA 236
+ + GAFY + + D R+ Q T+ + F
Sbjct: 399 EASERALARVLEELGLSYEINEGDGAFYGPKIDFHIKDALKRSHQCATIQLDFQMPEKFD 458
Query: 237 KAY-NILYEKEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIP 295
Y N L EK +H+ FG +R +I +G P +APIQV I+P+
Sbjct: 459 LTYINELNEKVRPV--VIHRAVFGSIDRFFGILIEHYGG----AFPVWLAPIQVQIIPV- 511
Query: 296 KKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVEN 355
+ +Y R+++ EL+ AGIR +D R ++ G+K + +++ +P + +G + +
Sbjct: 512 ----SHVHLDYCRKVQAELKQAGIRAGIDERNEKLGYKIRESQVQKIPYVLVLGDHEEQE 567
Query: 356 STVVLAR 362
+ V + R
Sbjct: 568 NAVNVRR 574
>pir||H82268 prolyl-tRNA synthetase VC0875 [imported] - Vibrio cholerae (group
O1 strain N16961) >gi|9655329|gb|AAF94037.1| (AE004172)
prolyl-tRNA synthetase [Vibrio cholerae]
Length = 571
Score = 83.5 bits (203), Expect = 5e-15
Identities = 52/162 (32%), Positives = 84/162 (51%), Gaps = 2/162 (1%)
Query: 221 RTLQIGTMHNYKQNFAKAYNILYEKEDGTHDYVHQTTFGMS-ERLLAAVIAIHGDDRGMV 279
R +++G + N+++ N +G + + +G+ R++AA I + DD G++
Sbjct: 407 RGIEVGHIFQLGTNYSEKMNCGVLDSNGKNVILEMGCYGIGVSRVVAAAIEQNHDDYGII 466
Query: 280 LPPTIAPIQVVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWEL 339
P IAP QV IVP+ K E V + A ++ EL AGI V D R++RPG F D EL
Sbjct: 467 WPDAIAPFQVAIVPM-NMHKSERVQQAAEKLYAELTAAGIEVLFDDRKERPGVMFSDMEL 525
Query: 340 KGVPVRIEVGPRDVENSTVVLARRDKLEKITIKREELVDKVR 381
GVP I +G R ++ R + EK + E ++D ++
Sbjct: 526 IGVPHTIIIGDRSMDEGHFEYKNRRQGEKEAVAMESIIDFIQ 567
>emb|CAA23560.1| (V00291) threonyl-tRNA synthetase (thrS; EC 6.1.1.3) [Escherichia
coli]
Length = 642
Score = 81.9 bits (199), Expect = 1e-14
Identities = 91/387 (23%), Positives = 166/387 (42%), Gaps = 55/387 (14%)
Query: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
GM W G I + +E F+ +++ +QEV P ++ ++K H ++ +F
Sbjct: 262 GMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTG-HWDNYKDAMFTT 320
Query: 93 THAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHT-RPLIR 151
+ E ++P + +F ++S+ DLP ++ + + +R E + L+R
Sbjct: 321 SSENRE-----YCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMR 375
Query: 152 VREISRFFEAHTAHAD----------------------FEDA--------ERQIKEDLEI 181
VR ++ +AH + FE E++I D E+
Sbjct: 376 VRGFTQD-DAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSD-EM 433
Query: 182 FDNLMKRLAIAYIISKRP-EWDKFPGAFYSLGAEVVMPD--GRTLQIGTMHNYKQNFAKA 238
+D LA+A + P E+ GAFY E + D R Q GT+ +
Sbjct: 434 WDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQ-LDFSLPSR 492
Query: 239 YNILYEKEDGTHDY---VHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIP 295
+ Y ED +H+ G ER I I ++ P +AP+QVVI+ I
Sbjct: 493 LSASYVGEDNERKVPVMIHRAILGSMERF----IGILTEEFAGFFPTWLAPVQVVIMNIT 548
Query: 296 KKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVEN 355
+ EY E+ ++L AGIRV D+R ++ G+K + L+ VP + G ++VE+
Sbjct: 549 DSQS-----EYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVES 603
Query: 356 STVVLARRDKLEKITIKREELVDKVRE 382
V + R + ++ E+++K+++
Sbjct: 604 GKVAVRTRRGKDLGSMDVNEVIEKLQQ 630
>dbj|BAA15486.1| (D90813) Threonine--tRNA ligase (EC 6.1.1.3) [Escherichia coli]
Length = 628
Score = 81.9 bits (199), Expect = 1e-14
Identities = 91/387 (23%), Positives = 166/387 (42%), Gaps = 55/387 (14%)
Query: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
GM W G I + +E F+ +++ +QEV P ++ ++K H ++ +F
Sbjct: 248 GMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTG-HWDNYKDAMFTT 306
Query: 93 THAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHT-RPLIR 151
+ E ++P + +F ++S+ DLP ++ + + +R E + L+R
Sbjct: 307 SSENRE-----YCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMR 361
Query: 152 VREISRFFEAHTAHAD----------------------FEDA--------ERQIKEDLEI 181
VR ++ +AH + FE E++I D E+
Sbjct: 362 VRGFTQD-DAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSD-EM 419
Query: 182 FDNLMKRLAIAYIISKRP-EWDKFPGAFYSLGAEVVMPD--GRTLQIGTMHNYKQNFAKA 238
+D LA+A + P E+ GAFY E + D R Q GT+ +
Sbjct: 420 WDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQ-LDFSLPSR 478
Query: 239 YNILYEKEDGTHDY---VHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIP 295
+ Y ED +H+ G ER I I ++ P +AP+QVVI+ I
Sbjct: 479 LSASYVGEDNERKVPVMIHRAILGSMERF----IGILTEEFAGFFPTWLAPVQVVIMNIT 534
Query: 296 KKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVEN 355
+ EY E+ ++L AGIRV D+R ++ G+K + L+ VP + G ++VE+
Sbjct: 535 DSQS-----EYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVES 589
Query: 356 STVVLARRDKLEKITIKREELVDKVRE 382
V + R + ++ E+++K+++
Sbjct: 590 GKVAVRTRRGKDLGSMDVNEVIEKLQQ 616
>sp|P00955|SYT_ECOLI THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
>gi|7428463|pir||SYECTT threonine--tRNA ligase (EC
6.1.1.3) - Escherichia coli >gi|5107656|pdb|1QF6|A Chain
A, Structure Of E. Coli Threonyl-Trna Synthetase
Complexed With Its Cognate Trna
>gi|1742811|dbj|BAA15498.1| (D90814) Threonine--tRNA
ligase (EC 6.1.1.3) [Escherichia coli]
>gi|1742818|dbj|BAA15504.1| (D90815) Threonine--tRNA
ligase (EC 6.1.1.3) [Escherichia coli]
>gi|1788013|gb|AAC74789.1| (AE000267) threonine tRNA
synthetase [Escherichia coli K12]
Length = 642
Score = 81.9 bits (199), Expect = 1e-14
Identities = 91/387 (23%), Positives = 166/387 (42%), Gaps = 55/387 (14%)
Query: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
GM W G I + +E F+ +++ +QEV P ++ ++K H ++ +F
Sbjct: 262 GMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTG-HWDNYKDAMFTT 320
Query: 93 THAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHT-RPLIR 151
+ E ++P + +F ++S+ DLP ++ + + +R E + L+R
Sbjct: 321 SSENRE-----YCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMR 375
Query: 152 VREISRFFEAHTAHAD----------------------FEDA--------ERQIKEDLEI 181
VR ++ +AH + FE E++I D E+
Sbjct: 376 VRGFTQD-DAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSD-EM 433
Query: 182 FDNLMKRLAIAYIISKRP-EWDKFPGAFYSLGAEVVMPD--GRTLQIGTMHNYKQNFAKA 238
+D LA+A + P E+ GAFY E + D R Q GT+ +
Sbjct: 434 WDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQ-LDFSLPSR 492
Query: 239 YNILYEKEDGTHDY---VHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIP 295
+ Y ED +H+ G ER I I ++ P +AP+QVVI+ I
Sbjct: 493 LSASYVGEDNERKVPVMIHRAILGSMERF----IGILTEEFAGFFPTWLAPVQVVIMNIT 548
Query: 296 KKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVEN 355
+ EY E+ ++L AGIRV D+R ++ G+K + L+ VP + G ++VE+
Sbjct: 549 DSQS-----EYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVES 603
Query: 356 STVVLARRDKLEKITIKREELVDKVRE 382
V + R + ++ E+++K+++
Sbjct: 604 GKVAVRTRRGKDLGSMDVNEVIEKLQQ 630
>pdb|1EVK|A Chain A, Crystal Structure Of A Truncated Form Of Threonyl-Trna
Synthetase With The Ligand Threonine
>gi|9955216|pdb|1EVK|B Chain B, Crystal Structure Of A
Truncated Form Of Threonyl-Trna Synthetase With The
Ligand Threonine >gi|9955217|pdb|1EVL|A Chain A, Crystal
Structure Of A Truncated Form Of Threonyl-Trna
Synthetase With A Threonyl Adenylate Analog
>gi|9955218|pdb|1EVL|B Chain B, Crystal Structure Of A
Truncated Form Of Threonyl-Trna Synthetase With A
Threonyl Adenylate Analog >gi|9955219|pdb|1EVL|C Chain
C, Crystal Structure Of A Truncated Form Of
Threonyl-Trna Synthetase With A Threonyl Adenylate
Analog >gi|9955220|pdb|1EVL|D Chain D, Crystal Structure
Of A Truncated Form Of Threonyl-Trna Synthetase With A
Threonyl Adenylate Analog
Length = 401
Score = 81.9 bits (199), Expect = 1e-14
Identities = 91/387 (23%), Positives = 166/387 (42%), Gaps = 55/387 (14%)
Query: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
GM W G I + +E F+ +++ +QEV P ++ ++K H ++ +F
Sbjct: 21 GMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTG-HWDNYKDAMFTT 79
Query: 93 THAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHT-RPLIR 151
+ E ++P + +F ++S+ DLP ++ + + +R E + L+R
Sbjct: 80 SSENRE-----YCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMR 134
Query: 152 VREISRFFEAHTAHAD----------------------FEDA--------ERQIKEDLEI 181
VR ++ +AH + FE E++I D E+
Sbjct: 135 VRGFTQD-DAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSD-EM 192
Query: 182 FDNLMKRLAIAYIISKRP-EWDKFPGAFYSLGAEVVMPD--GRTLQIGTMHNYKQNFAKA 238
+D LA+A + P E+ GAFY E + D R Q GT+ +
Sbjct: 193 WDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQ-LDFSLPSR 251
Query: 239 YNILYEKEDGTHDY---VHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIP 295
+ Y ED +H+ G ER I I ++ P +AP+QVVI+ I
Sbjct: 252 LSASYVGEDNERKVPVMIHRAILGSMERF----IGILTEEFAGFFPTWLAPVQVVIMNIT 307
Query: 296 KKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVEN 355
+ EY E+ ++L AGIRV D+R ++ G+K + L+ VP + G ++VE+
Sbjct: 308 DSQS-----EYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVES 362
Query: 356 STVVLARRDKLEKITIKREELVDKVRE 382
V + R + ++ E+++K+++
Sbjct: 363 GKVAVRTRRGKDLGSMDVNEVIEKLQQ 389
>pir||C81094 prolyl-tRNA synthetase NMB1339 [imported] - Neisseria meningitidis
(group B strain MD58) >gi|7226583|gb|AAF41714.1|
(AE002482) prolyl-tRNA synthetase [Neisseria
meningitidis MC58]
Length = 570
Score = 80.4 bits (195), Expect = 4e-14
Identities = 54/171 (31%), Positives = 88/171 (50%), Gaps = 9/171 (5%)
Query: 218 PDG-------RTLQIGTMHNYKQNFAKAYNILYEKEDGTHDYVHQTTFGMS-ERLLAAVI 269
PDG R +++G + + + +A N+ + +G + +G+ R++AA I
Sbjct: 395 PDGQGRLKLARGIEVGHVFQLRDKYTQAMNVSFLDNNGKSQIMEMGCYGIGITRVVAAAI 454
Query: 270 AIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKR 329
+ D++G++ +AP +VVIVP+ K K + V E A +I EL AG V LD R++R
Sbjct: 455 EQNNDEKGIIWTKAMAPFEVVIVPMNYK-KSDTVREAADKIYAELLAAGADVLLDDRDER 513
Query: 330 PGWKFYDWELKGVPVRIEVGPRDVENSTVVLARRDKLEKITIKREELVDKV 380
G D EL G+P RI +G R ++ V A R E + E+V +V
Sbjct: 514 AGVLLNDSELLGIPHRIVIGDRALKEGNVEYAERRDNEAQAVAIGEIVARV 564
>pir||G81400 proline--tRNA ligase (EC 6.1.1.15) Cj0543 [imported] -
Campylobacter jejuni (strain NCTC 11168)
>gi|6968011|emb|CAB75179.1| (AL139075) prolyl-tRNA
synthetase [Campylobacter jejuni]
Length = 569
Score = 78.0 bits (189), Expect = 2e-13
Identities = 47/167 (28%), Positives = 92/167 (54%), Gaps = 4/167 (2%)
Query: 217 MPDGRTLQIGTMHNYKQNFAKAYNILYEKEDGTHDYVHQTTFGMS-ERLLAAVIAIHGDD 275
+ + +++G + Q ++KA N + E+G + +G+ RLLA I + D+
Sbjct: 403 LKQSKGIEVGHIFKLGQKYSKAMNANFLDENGKSQPFYMGCYGIGVSRLLAVAIEANHDE 462
Query: 276 RGMVLPPTIAPIQVVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFY 335
+G + T+AP + I+ K+++ + E+A ++ +L G+ V LD R +R G K
Sbjct: 463 KGCIWNKTLAPFVLEIIVSNLKDEKAL--EFANKLYRDLTNLGLEVLLDDRNERFGVKMN 520
Query: 336 DWELKGVPVRIEVGPRDVENSTVVLARRDKLEKITIKREELVDKVRE 382
D+EL G P + +G + +EN+ + L +R+ L K IK +EL++ +++
Sbjct: 521 DFELMGFPYALVIG-KGLENNEIELIQREGLVKELIKTDELMEILKK 566
>sp|Q9WZJ9|SYT_THEMA THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
>gi|7437519|pir||G72339 threonine--tRNA ligase (EC
6.1.1.3) - Thermotoga maritima (strain MSB8)
>gi|4981265|gb|AAD35821.1|AE001744_11 (AE001744)
threonyl-tRNA synthetase [Thermotoga maritima]
Length = 640
Score = 77.6 bits (188), Expect = 3e-13
Identities = 84/385 (21%), Positives = 157/385 (39%), Gaps = 54/385 (14%)
Query: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
GM +LP G+ ++ + KF E G+QE+ P LI + K + H + +++I
Sbjct: 260 GMPFFLPKGVVVLNELMKFSRELHRERGYQEIFTP-LIMNEQLWKISGHWDHYAENMYFI 318
Query: 93 THAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHT-RPLIR 151
E + + ++P + ++ S+ DLP + ++ V+RYE L+R
Sbjct: 319 -----EKDEERYAVKPMNCPGHILVYKSRTVSYRDLPLRFFEFGRVHRYERSGVLHGLMR 373
Query: 152 VREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKRLAIAYII--SKRPE--------W 201
VR ++ +AH + E +I L++ + + + Y + S PE W
Sbjct: 374 VRSFTQ-DDAH-IFCTPDQIEEEILGVLDLINTIYSQFGFTYRVELSTMPEDHMGDEAIW 431
Query: 202 DKF--------------------PGAFYSLGAEVVMPD--GRTLQIGTMHNYKQNFAKAY 239
+K GAFY + + D GR Q T+ + +
Sbjct: 432 EKATTALKNALERAGLSYKVNEGEGAFYGPKIDFHIRDSIGREWQCATI-QLDFMMPEKF 490
Query: 240 NILYEKEDGTHD---YVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPK 296
N+ Y D +H+ +G ER +I + P +APIQV ++PI +
Sbjct: 491 NVTYIGPDNKEHRAVMIHRAIYGSLERFFGILI----EHFAGAFPTWLAPIQVAVIPISE 546
Query: 297 KEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVENS 356
K + A ++ + G RV D R + G++ + + +P I +G +++E+
Sbjct: 547 KHN-----DGAEKVARRISQEGFRVFFDNRRETLGYRIRQAQTQKIPYMIIIGDKELESG 601
Query: 357 TVVLARRDKLEKITIKREELVDKVR 381
+ + R E + E V+ +R
Sbjct: 602 KISVRTRTGKEIKDVDPEHFVETLR 626
>pir||D81847 proline--tRNA ligase (EC 6.1.1.15) NMA1553 [imported] - Neisseria
meningitidis (group A strain Z2491)
>gi|7380194|emb|CAB84780.1| (AL162756) prolyl-tRNA
synthetase [Neisseria meningitidis Z2491]
Length = 570
Score = 77.6 bits (188), Expect = 3e-13
Identities = 54/171 (31%), Positives = 87/171 (50%), Gaps = 9/171 (5%)
Query: 218 PDG-------RTLQIGTMHNYKQNFAKAYNILYEKEDGTHDYVHQTTFGMS-ERLLAAVI 269
PDG R +++G + + + +A N+ + +G + +G+ R++AA I
Sbjct: 395 PDGQGRLKLARGIEVGHVFQLRDKYTQAMNVSFLDNNGKSQIMEMGCYGIGITRVVAAAI 454
Query: 270 AIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKR 329
+ D++G++ +A +VVIVP+ K K + V E A +I EL AG V LD R++R
Sbjct: 455 EQNNDEKGIIWTKAMASFEVVIVPMNYK-KSDTVREAADKIYAELLAAGADVLLDDRDER 513
Query: 330 PGWKFYDWELKGVPVRIEVGPRDVENSTVVLARRDKLEKITIKREELVDKV 380
G D EL G+P RI +G R ++ V A R E I E+V +V
Sbjct: 514 AGVLLNDSELLGIPHRIVIGDRALKEGNVEYAERRDNEAQAIAIGEIVARV 564
>sp|O05947|SYT_RICPR THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
>gi|7437518|pir||E71733 threonine--tRNA ligase (EC
6.1.1.3) - Rickettsia prowazekii
>gi|2073475|emb|CAA72469.1| (Y11780) threonyl-tRNA
synthetase [Rickettsia prowazekii]
>gi|3860783|emb|CAA14684.1| (AJ235270) THREONYL-TRNA
SYNTHETASE (thrS) [Rickettsia prowazekii]
Length = 635
Score = 76.5 bits (185), Expect = 6e-13
Identities = 88/389 (22%), Positives = 167/389 (42%), Gaps = 57/389 (14%)
Query: 32 KGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFW 91
+GM W G I IE++I +++ + G+ EV P L+ ++ ++ H A F ++F
Sbjct: 260 QGMVFWHDKGWSIYNTIEQYIRKKIRKNGYIEVKTPVLVDKSLWEASG-HWAKFRCDMFT 318
Query: 92 ITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHT-RPLI 150
+ E D L L+P + +F I+S+ DLP ++ + +R E L+
Sbjct: 319 L-----ETDDKTLALKPMNCPCHVQIFKQGIKSYRDLPLRMSEFGLCHRNEASGALHGLM 373
Query: 151 RVREISRFFEAHTAHADFEDAERQIK---------EDLEIFDNLMKRLAIAYIISKRPE- 200
RVR + + +AH A+ + + ++ +D D +K + I + E
Sbjct: 374 RVRSLVQD-DAHIFCAEEQITDETVRFCKLLTEVYKDFGFTDIKVKFSDRSEICAGNDEV 432
Query: 201 WDKF------------------PG--AFYSLGAEVVMPD--GRTLQIGTMHNYKQNFA-- 236
WDK PG AFY E V+ D GR Q GT+ + +F
Sbjct: 433 WDKAENALKTAIEKAGFIYTLNPGEAAFYGPKIEFVLTDAIGRQWQCGTL---QMDFVLP 489
Query: 237 ---KAYNILYEKEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVP 293
A I E +H+ G ER + +I ++ P +AP+QV I
Sbjct: 490 ERLDANYIAASGEKKRPVMLHRAILGSLERFIGILI----EEYAGKFPIWLAPVQVAIAT 545
Query: 294 IPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDV 353
I + +YA E+++ L G+R +++ + +K ++ + +P+ +G ++
Sbjct: 546 ITND-----LNDYALEVQKTLIDNGVRTDINISPDKINYKIREFSNQKIPIIAVIGKQEQ 600
Query: 354 ENSTVVLARRDKLEKITIKREELVDKVRE 382
N V + + +E+ + E+L+ +++
Sbjct: 601 ANKQVTIRKLGTIEQEILSIEQLIAMIKK 629
>pir||H72368 proline--tRNA ligase (EC 6.1.1.15) - Thermotoga maritima (strain
MSB8) >gi|4981026|gb|AAD35599.1|AE001727_11 (AE001727)
prolyl-tRNA synthetase [Thermotoga maritima]
Length = 577
Score = 76.5 bits (185), Expect = 6e-13
Identities = 50/163 (30%), Positives = 82/163 (49%), Gaps = 6/163 (3%)
Query: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
G+ +LP G +++ IE + EEM R G QE+L P L P E K++ + E+ +
Sbjct: 38 GIYTYLPLGRRVLLKIENIVREEMNRIGAQEILMPILQP-AELWKQSGRWDDYGPEMMKL 96
Query: 93 THAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHTRPLIRV 152
HE L PT E + + +RS+ LP +YQI N YR E + L+R
Sbjct: 97 KDR-HER---DFTLGPTHEEIVTDLVKNELRSYKQLPLTLYQIANKYRDEIRPRFGLLRA 152
Query: 153 REISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKRLAIAYII 195
RE +A++ HA +E + ++ + + +M+RL + Y+I
Sbjct: 153 REFI-MKDAYSFHASWESLDETYEQFKKAYSRIMERLGVRYMI 194
>sp|P56071|SYT_HELPY THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
>gi|7437522|pir||C64535 threonine--tRNA ligase (EC
6.1.1.3) - Helicobacter pylori (strain 26695)
>gi|2313207|gb|AAD07192.1| (AE000534) threonyl-tRNA
synthetase (thrS) [Helicobacter pylori 26695]
Length = 612
Score = 76.1 bits (184), Expect = 8e-13
Identities = 83/391 (21%), Positives = 168/391 (42%), Gaps = 54/391 (13%)
Query: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
G+ +WLP G ++ K IE + + + G++ V P ++ +++ K + H ++ +++
Sbjct: 238 GLPLWLPKGARLRKRIEDLLSQALLLRGYEPVKGPEIL-KSDVWKISGHYDNYKENMYFT 296
Query: 93 THAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHT-RPLIR 151
T E ++P + ++ + S+ DLP + Y+ V+R+E L+R
Sbjct: 297 TIDEQE-----YGIKPMNCVGHIKVYQSALHSYRDLPLRFYEYGVVHRHEKSGVLHGLLR 351
Query: 152 VREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKRLAIAY--IISKRPE--------W 201
VRE ++ +AH FE + ++ L+ +M+ +Y +S RP W
Sbjct: 352 VREFTQ-DDAH-IFCSFEQIQSEVSAILDFTHKIMQAFDFSYEMELSTRPAKSIGDDKVW 409
Query: 202 DKFP--------------------GAFYSLGAEVVMPDG--RTLQIGTMH---NYKQNFA 236
+K GAFY ++ + D R Q GT+ N + F
Sbjct: 410 EKATNALKEALKEHRIDYKIDEGGGAFYGPKIDIKITDALKRKWQCGTIQVDMNLPERFK 469
Query: 237 KAYNILYEKEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPK 296
A+ Y + +H+ G ER IAI + G P +AP Q+ ++PI +
Sbjct: 470 LAFTNEYNHAE-QPVMIHRAILGSFERF----IAILSEHFGGNFPFFVAPTQIALIPINE 524
Query: 297 KEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVENS 356
+ + +A +++E L+ I V + + K E + +P+ + +G +VE
Sbjct: 525 EH-----HVFALKLKEALKKRDIFVEVLDKNDSLNKKVRLAEKQKIPMILVLGNEEVETE 579
Query: 357 TVVLARRDKLEKITIKREELVDKVRELFDDI 387
+ + R+K ++ + +E ++ V ++
Sbjct: 580 ILSIRDREKQDQYKMPLKEFLNMVESKMQEV 610
>sp|P56124|SYP_HELPY PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE) (PRORS)
>gi|7437709|pir||F64549 proline--tRNA ligase (EC
6.1.1.15) - Helicobacter pylori (strain 26695)
>gi|2313329|gb|AAD07305.1| (AE000543) prolyl-tRNA
synthetase (proS) [Helicobacter pylori 26695]
Length = 577
Score = 76.1 bits (184), Expect = 8e-13
Identities = 51/166 (30%), Positives = 83/166 (49%), Gaps = 3/166 (1%)
Query: 221 RTLQIGTMHNYKQNFAKAYNILYEKEDGTHDYVHQTTFGMS-ERLLAAVIAIHGDDRGMV 279
++L++G + Q +AK+ + ++G + +G+ RLL+A++ DD G V
Sbjct: 412 KSLEVGHIFKLGQGYAKSLKASFLDKNGKEQFFEMGCYGIGISRLLSAILEQKSDDLGCV 471
Query: 280 LPPTIAPIQVVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWEL 339
AP VVIV K E + A E+ E L G+ LD R+ R G K D+EL
Sbjct: 472 WTKNTAPFDVVIVV--SNWKDEAQKKLAFEVYERLLQKGVDALLDDRDARFGAKMRDFEL 529
Query: 340 KGVPVRIEVGPRDVENSTVVLARRDKLEKITIKREELVDKVRELFD 385
G + + +G + +E+ +R LEK TIK EL +K+ E+ +
Sbjct: 530 IGERLALIIGKQTLESKEFECIKRANLEKQTIKDIELEEKILEMLE 575
>sp|Q9ZMV3|SYT_HELPJ THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
>gi|7437521|pir||G71972 threonine--tRNA ligase (EC
6.1.1.3) - Helicobacter pylori (strain J99)
>gi|4154621|gb|AAD05692.1| (AE001450) THREONYL-TRNA
SYNTHETASE [Helicobacter pylori J99]
Length = 612
Score = 76.1 bits (184), Expect = 8e-13
Identities = 83/391 (21%), Positives = 167/391 (42%), Gaps = 54/391 (13%)
Query: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
G+ +WLP G ++ K IE + + + G++ V P ++ +++ K + H ++ +++
Sbjct: 238 GLPLWLPKGARLRKRIEDLLSQALLLRGYEPVKGPEIL-KSDVWKISGHYDNYKENMYFT 296
Query: 93 THAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHT-RPLIR 151
T E ++P + ++ + S+ DLP + Y+ V+R+E L+R
Sbjct: 297 TIDEQE-----YGIKPMNCVGHIKVYQSALHSYRDLPLRFYEYGVVHRHEKSGVLHGLLR 351
Query: 152 VREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKRLAIAY--IISKRPE--------W 201
VRE ++ +AH FE + ++ L+ +M+ +Y +S RP W
Sbjct: 352 VREFTQ-DDAH-IFCSFEQIQSEVSAILDFTHKIMQAFGFSYEMELSTRPAKSIGDDKVW 409
Query: 202 DKFP--------------------GAFYSLGAEVVMPDG--RTLQIGTMH---NYKQNFA 236
+K GAFY ++ + D R Q GT+ N + F
Sbjct: 410 EKATNALKEALKEHRIDYKIDEGGGAFYGPKIDIKITDALKRKWQCGTIQVDMNLPERFK 469
Query: 237 KAYNILYEKEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPK 296
A+ Y + +H+ G ER IAI + G P +AP Q+ ++PI +
Sbjct: 470 LAFTNEYNHAE-QPVMIHRAILGSFERF----IAILSEHFGGNFPFFVAPTQIALIPINE 524
Query: 297 KEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVENS 356
+ + +A +++E L+ I V + + K E + +P+ + +G +VE
Sbjct: 525 EH-----HVFALKLKEALKKCDIFVEVLDKNDSLNKKVRLAEKQKIPMILVLGNEEVETE 579
Query: 357 TVVLARRDKLEKITIKREELVDKVRELFDDI 387
+ + R+K + + +E ++ V ++
Sbjct: 580 ILSIRDREKQAQYKMPLKEFLNMVESKMQEV 610
>pir||F83303 threonyl-tRNA synthetase PA2744 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9948822|gb|AAG06132.1|AE004702_9
(AE004702) threonyl-tRNA synthetase [Pseudomonas
aeruginosa]
Length = 640
Score = 76.1 bits (184), Expect = 8e-13
Identities = 84/375 (22%), Positives = 149/375 (39%), Gaps = 67/375 (17%)
Query: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
GM W P G + + +E+++ + G+ EV P ++ +++ H + + +F
Sbjct: 261 GMVFWHPNGWSVYQVLEQYMRKVQRDHGYVEVRTPQVVDRILWERSG-HWSNYAENMFTT 319
Query: 93 THAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHT-RPLIR 151
+ + ++P + +F ++S+ DLP ++ + +R E ++R
Sbjct: 320 SSESRD-----YAVKPMNCPCHVQIFNQGLKSYRDLPLRLAEFGACHRNEPSGALHGIMR 374
Query: 152 VREISRFFEAHT---------AHADFEDAERQIKEDLEIFDNLMKRLAIAYIISKRPE-- 200
VR ++ +AH ADF Q+ D D MK +S RP
Sbjct: 375 VRGFTQD-DAHIFCTEEQVKKEAADFIKLTLQVYRDFGFTDIAMK-------LSTRPAKR 426
Query: 201 ------WDKFPGA--------------------FYSLGAEVVMPD--GRTLQIGTMHNYK 232
WD+ GA FY E + D GR Q GT+ Y
Sbjct: 427 VGSDELWDRAEGALADALNESGLAWEYQPGEGAFYGPKIEFTLKDCLGRNWQCGTLQ-YD 485
Query: 233 QNFAKAYNILYEKEDGTHD---YVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQV 289
N + + Y ED +H+ G ER + +I + P +AP Q
Sbjct: 486 PNLPERLDASYIAEDNNRKRPVMLHRAILGSFERFIGMLIEHYAG----AFPAWLAPTQA 541
Query: 290 VIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVG 349
V++ I K+ ++A E+ L +G R D+R ++ G+K + L VP + +G
Sbjct: 542 VVMNITDKQA-----DFAAEVVRILGESGFRAKSDLRNEKIGFKIREHTLLKVPYLLVIG 596
Query: 350 PRDVENSTVVLARRD 364
R+VE+ V + R+
Sbjct: 597 DREVESKAVAVRTRE 611
>pir||A82479 threonyl-tRNA synthetase VCA0287 [imported] - Vibrio cholerae
(group O1 strain N16961) >gi|9657684|gb|AAF96196.1|
(AE004368) threonyl-tRNA synthetase [Vibrio cholerae]
Length = 642
Score = 74.9 bits (181), Expect = 2e-12
Identities = 82/386 (21%), Positives = 159/386 (40%), Gaps = 55/386 (14%)
Query: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
GM W G I +++E FI +++ G+QEV P ++ +++ H + +F
Sbjct: 263 GMVFWHHNGWSIFRDLEIFIRQKLNEYGYQEVKGPLMMDRVLWERSG-HWDKYADAMFTT 321
Query: 93 THAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHT-RPLIR 151
+ E ++P + +F ++S+ DLP ++ + + +R E + ++R
Sbjct: 322 SSENRE-----YAIKPMNCPGHIQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGIMR 376
Query: 152 VREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKRLAIAYIISK---RPE-------- 200
VR ++ +AH + + ++++ +++ + I+ K RPE
Sbjct: 377 VRGFTQD-DAHIFCTE-DQIQQEVTSCIKMVYDTYTTFGFQNIVVKLSTRPEKRVGSDEI 434
Query: 201 WDKFP--------------------GAFYSLGAEVVMPD--GRTLQIGTMHNYKQNFAKA 238
WDK GAFY E + D R Q GT+ N
Sbjct: 435 WDKSEQALIDSLKAMDIPFEIQEGEGAFYGPKIEFTLYDCLDRAWQCGTVQ-LDFNLPTR 493
Query: 239 YNILYEKEDGTH---DYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIP 295
Y E +H+ G ER + +I ++ P +AP Q V+V I
Sbjct: 494 LGATYVGESNERLIPVMIHRAILGSLERFIGILI----EEYAGFFPTWLAPEQAVVVNIT 549
Query: 296 KKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVEN 355
K+ +YA E+ ++L+ GIR D+R ++ G+K + LK VP + G +++E
Sbjct: 550 DKQA-----DYAHEVAQKLQKCGIRAKADLRNEKIGFKIREHTLKRVPYMLVCGDQEMEA 604
Query: 356 STVVLARRDKLEKITIKREELVDKVR 381
+ + R + K ++ + ++
Sbjct: 605 GEIAVRTRKGKDLGKFKLDDFIAHIQ 630
>sp|Q9ZMJ6|SYP_HELPJ PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE) (PRORS)
>gi|7437708|pir||B71959 proline--tRNA ligase (EC
6.1.1.15) - Helicobacter pylori (strain J99)
>gi|4154734|gb|AAD05795.1| (AE001460) PROLYL-TRNA
SYNTHETASE [Helicobacter pylori J99]
Length = 576
Score = 73.7 bits (178), Expect = 4e-12
Identities = 51/164 (31%), Positives = 82/164 (49%), Gaps = 3/164 (1%)
Query: 221 RTLQIGTMHNYKQNFAKAYNILYEKEDGTHDYVHQTTFGMS-ERLLAAVIAIHGDDRGMV 279
++L++G + Q++AK+ + ++G + +G+ RLL+ ++ DD G V
Sbjct: 411 KSLEVGHIFKLGQSYAKSLKASFLDKNGKERFFEMGCYGIGISRLLSVILEQKSDDLGCV 470
Query: 280 LPPTIAPIQVVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWEL 339
AP VVIV K E + A E+ E L G+ LD R+ R G K D+EL
Sbjct: 471 WTKNTAPFDVVIVV--SNLKDEAQKKLAFEVYERLLQKGVDALLDDRDARFGAKMRDFEL 528
Query: 340 KGVPVRIEVGPRDVENSTVVLARRDKLEKITIKREELVDKVREL 383
G + + VG + +E+ +R LEK TIK EL +K+ E+
Sbjct: 529 IGERLALIVGKQTLESKEFECIKRANLEKQTIKDIELEEKILEM 572
>sp|O83195|SYP_TREPA PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE) (PRORS)
>gi|7437711|pir||F71359 proline--tRNA ligase (EC
6.1.1.15) (proS) - syphilis spirochete
>gi|3322426|gb|AAC65149.1| (AE001200) prolyl-tRNA
synthetase (proS) [Treponema pallidum]
Length = 617
Score = 73.4 bits (177), Expect = 6e-12
Identities = 39/124 (31%), Positives = 67/124 (53%), Gaps = 4/124 (3%)
Query: 224 QIGTMHNYKQNFAKAYNILYEKEDGTHDYVHQTTFGMS-ERLLAAVIAIHGDDRGMVLPP 282
++G + + ++ ++ + E G + +G+ +R LA+V+ H D RG+ P
Sbjct: 452 ELGHLFKLGDKYTRSMHLTFTDEQGVRQFPLMGCYGIGLDRTLASVVENHHDTRGISWPL 511
Query: 283 TIAPIQVVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGV 342
I+P VV++PIP + Y A + +LRT G+ V D R +RPG KF D +L G+
Sbjct: 512 AISPYAVVLIPIPHTQAP---YAAAEALYVQLRTRGVEVLFDDRAERPGVKFADADLIGI 568
Query: 343 PVRI 346
P+R+
Sbjct: 569 PLRV 572
>sp|O83809|SYT_TREPA THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
>gi|7437525|pir||B71275 threonine--tRNA ligase (EC
6.1.1.3) (thrS) - syphilis spirochete
>gi|3323150|gb|AAC65804.1| (AE001254) threonyl-tRNA
synthetase (thrS) [Treponema pallidum]
Length = 592
Score = 73.4 bits (177), Expect = 6e-12
Identities = 91/383 (23%), Positives = 151/383 (38%), Gaps = 67/383 (17%)
Query: 25 LDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAG 84
LD+ P G W P G + I++++ M G+ EV P ++P++ +++ H
Sbjct: 206 LDEENP--GQVFWHPEGWTLYVAIQQYLRRVMHEDGYAEVHTPFVMPQSLWERSG-HWDK 262
Query: 85 FEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETK 144
+ ++ E L+P + +F RS+ DLP ++ + + R E
Sbjct: 263 YRANMYLT-----EGEKRSFALKPMNCPGHVEIFKQKTRSYRDLPLRLSEFGSCTRNEPS 317
Query: 145 HT-RPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKRL---------AIAYI 194
+ ++RVR F AH +A QI ++ F L+ R+ I
Sbjct: 318 GSLHGVMRVRG----FVQDDAHIFCTEA--QIASEVTRFCRLLARVYADFGFAQEQIRVK 371
Query: 195 ISKRPE--------WDKFP--------------------GAFYSLGAEVVMPDG--RTLQ 224
S RPE WD+ GAFY E + D R Q
Sbjct: 372 FSTRPEQRIGDDATWDRAERALAEACEAAGLSYEHAPGEGAFYGPKLEFALIDTLEREWQ 431
Query: 225 IGTMH-NYKQNFAKAYNILYEKEDGTHDY---VHQTTFGMSERLLAAVIAIHGDDRGMVL 280
GT+ +Y+ + N Y ED +H+T G ER + +I +G
Sbjct: 432 CGTIQVDYQLPSCERLNAEYVGEDNQRHMPVILHRTVIGSLERFIGILIEHYGG----AF 487
Query: 281 PPTIAPIQVVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELK 340
PP +AP+Q V++P+ EYA+ + EL +RV D+ +R K + +
Sbjct: 488 PPWLAPVQAVVIPVAPA-----FLEYAQHVARELCARSLRVQADVSAERMNAKIRTAQTQ 542
Query: 341 GVPVRIEVGPRDVENSTVVLARR 363
VP + VG R++ V + R
Sbjct: 543 KVPYLLIVGERELRAQQVAVRPR 565
>sp|P43014|SYT_HAEIN THREONYL-TRNA SYNTHETASE (THREONINE--TRNA LIGASE) (THRRS)
>gi|1075350|pir||H64119 threonine--tRNA ligase (EC
6.1.1.3) - Haemophilus influenzae
>gi|1574199|gb|AAC23014.1| (U32816) threonyl-tRNA
synthetase (thrS) [Haemophilus influenzae Rd]
Length = 643
Score = 73.0 bits (176), Expect = 7e-12
Identities = 82/385 (21%), Positives = 160/385 (41%), Gaps = 59/385 (15%)
Query: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
GM W G I + +E F+ ++++ +QEV P ++ ++K H + +F
Sbjct: 262 GMVFWHNDGWTIFRELETFVRTKLKQYDYQEVKGPFMMDRVLWEKTG-HWQNYADLMFTT 320
Query: 93 THAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHT-RPLIR 151
E ++P + +F ++S+ DLP ++ + + +R E + L+R
Sbjct: 321 QSENRE-----YAIKPMNCPGHVQIFNQGLKSYRDLPIRMAEFGSCHRNEPSGSLHGLMR 375
Query: 152 VREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKRLA---IAYIISKRPE-------- 200
VR ++ +AH + + E ++ +++ ++ IA +S RPE
Sbjct: 376 VRGFTQD-DAHIFCTE-DQIESEVTSCIKMVYDIYSTFGFTNIAVKLSTRPENRIGSDEM 433
Query: 201 WDKFP--------------------GAFYSLGAEVVMPD--GRTLQIGTMHNYKQNFAKA 238
WD+ GAFY E + D GR Q GT+ + +FA
Sbjct: 434 WDRAEAGLAAALAHNGLEYEIQEGEGAFYGPKIEFALRDCLGREWQCGTV---QLDFALP 490
Query: 239 YNI--LYEKEDGTHD---YVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVP 293
+ Y ED + +H+ G ER + + ++ P +AP Q V++
Sbjct: 491 GRLDATYVAEDNSRKTPVMIHRAILGSIERFIGIIT----EEYAGFFPAWLAPTQAVVMN 546
Query: 294 IPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDV 353
I + +Y +++ ++L G+RV D+R ++ G+K + L+ VP + G +++
Sbjct: 547 ITDSQA-----DYVQKVAKQLSDVGLRVKTDLRNEKVGFKIREHTLRRVPYMLVCGDKEI 601
Query: 354 ENSTVVLARRDKLEKITIKREELVD 378
V + R + T EE +
Sbjct: 602 AEGKVAVRTRKGADLGTFTVEEFAE 626
>pir||F70332 proline-tRNA synthetase - Aquifex aeolicus
>gi|2983039|gb|AAC06648.1| (AE000686) proline-tRNA
synthetase [Aquifex aeolicus]
Length = 570
Score = 72.2 bits (174), Expect = 1e-11
Identities = 48/170 (28%), Positives = 88/170 (51%), Gaps = 4/170 (2%)
Query: 221 RTLQIGTMHNYKQNFAKAYNILYEKEDGTHDYVHQTTFGMS-ERLLAAVIAIHGDDRGMV 279
R L++G + +++ + DG + +G+ R+LAA++ + DD+G+
Sbjct: 404 RGLELGHIFLLGTRYSEPMKAYFTDRDGKEKPIIMGCYGIGVSRILAALVEQYHDDKGIK 463
Query: 280 LPPTIAPIQVVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWEL 339
P +AP ++ I+ + K+++ + A ++ E GI V D RE+ PG+KF D +L
Sbjct: 464 WPTPVAPFELDIILLNTKDEE--MKNVAEKLYLEAEEKGIDVIFDDREESPGFKFADADL 521
Query: 340 KGVPVRIEVGPRDVENSTVVLARRDKLEKITIKREELVDKVRELFDDIMK 389
G P RI VG + V+ V + R EK ++ E+ +D V+E ++ K
Sbjct: 522 VGFPYRIVVG-KKVKEGKVEVQSRHTGEKWDVEIEKAIDFVKEKIEEDKK 570
>sp|P57333|SYP_BUCAI PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE) (PRORS)
>gi|10038919|dbj|BAB12954.1| (AP001118) prolyl-tRNA
synthetase [Buchnera sp. APS]
Length = 572
Score = 72.2 bits (174), Expect = 1e-11
Identities = 45/157 (28%), Positives = 83/157 (52%), Gaps = 2/157 (1%)
Query: 221 RTLQIGTMHNYKQNFAKAYNILYEKEDGTHDYVHQTTFGMS-ERLLAAVIAIHGDDRGMV 279
++++IG + Q +++ + ++G ++ +G+ R+ AAVI H D G++
Sbjct: 407 QSIEIGHIFQLGQKYSRKIQQSVKIKNGNLKNLYMGCYGIGITRIAAAVIEQHHDKNGII 466
Query: 280 LPPTIAPIQVVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWEL 339
P +IAP +VVI+PI K+ +I A + ++ + GI V LD R++RPG F + +L
Sbjct: 467 WPDSIAPFEVVILPINMKKDNKIKI-IAHFLYKKFKKTGIDVILDDRDERPGVMFNEVDL 525
Query: 340 KGVPVRIEVGPRDVENSTVVLARRDKLEKITIKREEL 376
G+P +I + R + V R E I I +++
Sbjct: 526 IGIPHQIIISKRSINYDNVEYRERKNKENILINIKDI 562
>dbj|BAB06138.1| (AP001515) prolyl-tRNA synthetase [Bacillus halodurans]
Length = 569
Score = 71.8 bits (173), Expect = 2e-11
Identities = 52/174 (29%), Positives = 93/174 (52%), Gaps = 14/174 (8%)
Query: 209 YSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYNILYEKEDGTHDYVHQTTFGMS-ERLLAA 267
++ G EV G+ ++GT+++ K + E+G + +G+ R++AA
Sbjct: 401 FAQGIEV----GQVFKLGTVYSEK------LGATFLDENGKSQPMLMGCYGIGVSRMVAA 450
Query: 268 VIAIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMRE 327
VI H D+ G+V P ++AP V ++ + K+++++ + A + L+ AG+ V LD R
Sbjct: 451 VIEQHHDEDGIVWPTSVAPFDVHVLALNVKKEEQM--KLADSVYHSLQQAGLDVLLDDRP 508
Query: 328 KRPGWKFYDWELKGVPVRIEVGPRDVENSTVVLARRDKLEKITIKREELVDKVR 381
+R G KF D +L G+P+R+ VG R E V R+ E I + +ELV ++
Sbjct: 509 ERAGVKFKDADLIGLPLRVAVGKRADEGYVEVKVRKTG-EVIEVHADELVPTIQ 561
>sp|O05814|SYP_MYCTU PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE) (PRORS)
>gi|7437716|pir||H70588 probable proS protein -
Mycobacterium tuberculosis (strain H37RV)
>gi|2078014|emb|CAB08445.1| (Z95207) proS [Mycobacterium
tuberculosis]
Length = 582
Score = 71.4 bits (172), Expect = 2e-11
Identities = 48/168 (28%), Positives = 81/168 (47%), Gaps = 16/168 (9%)
Query: 33 GMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWI 92
G+ WLP GL++++NIE+ I +EM G QE+LFPAL+P + + + VF +
Sbjct: 40 GLYSWLPLGLRVLRNIERVIRDEMNAIGGQEILFPALLPRAPY-ETTNRWTQYGDSVFRL 98
Query: 93 -THAGHEPLDVKLILRPTSETAMYSMFALWIR----SHADLPFKVYQIVNVYRYETKHTR 147
G++ +L PT E +F L ++ S+ D P +YQI YR E +
Sbjct: 99 KDRRGND-----YLLGPTHE----ELFTLTVKGEYSSYKDFPLTLYQIQTKYRDEARPRA 149
Query: 148 PLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKRLAIAYII 195
++R RE ++++ D + E + + RL + Y+I
Sbjct: 150 GILRAREFV-MKDSYSFDIDAAGLKAAYHAHREAYQRIFDRLQVRYVI 196
>pir||C83527 prolyl-tRNA synthetase PA0956 [imported] - Pseudomonas aeruginosa
(strain PAO1) >gi|9946862|gb|AAG04345.1|AE004529_11
(AE004529) prolyl-tRNA synthetase [Pseudomonas
aeruginosa]
Length = 571
Score = 70.6 bits (170), Expect = 4e-11
Identities = 51/175 (29%), Positives = 85/175 (48%), Gaps = 12/175 (6%)
Query: 218 PDG-------RTLQIGTMHNYKQNFAKAYNILYEKEDGTHDYVHQTTFGMS-ERLLAAVI 269
PDG R +++G + +++A + E G + +G+ R++AA I
Sbjct: 395 PDGKGTLVIKRGIEVGHIFQLGTKYSEAMKLSVLSEQGKPVNLIMGCYGIGVSRVVAAAI 454
Query: 270 AIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKR 329
+ D+RG++ P +AP Q+ +VP+ K + E V + ++ EL AG V LD R+K+
Sbjct: 455 EQNHDERGILWPSALAPFQIALVPL--KYETESVKQATDKLYAELTAAGFEVLLDDRDKK 512
Query: 330 --PGWKFYDWELKGVPVRIEVGPRDVENSTVVLARRDKLEKITIKREELVDKVRE 382
PG KF D EL G+P RI + R + + R E + EL+ + E
Sbjct: 513 TSPGVKFADMELIGIPHRIVISDRGLSEGVLEYKGRRDSESQNLPIGELMSFITE 567
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.321 0.139 0.418
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 188689985
Number of Sequences: 2977
Number of extensions: 8290278
Number of successful extensions: 22745
Number of sequences better than 1.0e-10: 73
Number of HSP's better than 0.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 22510
Number of HSP's gapped (non-prelim): 102
length of query: 480
length of database: 189,106,746
effective HSP length: 54
effective length of query: 426
effective length of database: 156,788,448
effective search space: 66791878848
effective search space used: 66791878848
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 167 (69.5 bits)