BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1728 (tyrS) DE:tyrosyl-tRNA synthetase (tyrS)
(375 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||B75072 tyrosyl-tRNA synthetase (tyrs) PAB1728 - Pyrococcus ... 764 0.0
pir||F71093 tyrosine--tRNA ligase (EC 6.1.1.1) - Pyrococcus hori... 735 0.0
pir||E72512 probable tyrosyl-tRNA synthetase APE2074 - Aeropyrum... 304 9e-82
gb|AAK40439.1| Tyrosyl-tRNA synthetase (tyrS) [Sulfolobus solfat... 281 8e-75
sp|P95982|SYY_SULSO TYROSYL-TRNA SYNTHETASE (TYROSINE--TRNA LIGA... 281 8e-75
pir||T03741 probable tyrosine--tRNA ligase (EC 6.1.1.1) - common... 224 2e-57
gb|AAC69137.1| (U78721) putative tyrosyl-tRNA synthetase [Arabid... 216 4e-55
gi|11498382 tyrosyl-tRNA synthetase (tyrS) [Archaeoglobus fulgid... 213 2e-54
gb|AAF16759.1|AC010155_12 (AC010155) F3M18.22 [Arabidopsis thali... 206 4e-52
sp|Q57834|SYY_METJA TYROSYL-TRNA SYNTHETASE (TYROSINE--TRNA LIGA... 200 2e-50
emb|CAC11652.1| (AL445064) probable tyrosyl-tRNA synthetase [The... 196 3e-49
sp|O27795|SYY_METTH TYROSYL-TRNA SYNTHETASE (TYROSINE--TRNA LIGA... 191 1e-47
emb|CAB94018.1| (AL358652) tyrosyl-tRNA synthetase isolog [Leish... 190 2e-47
gb|AAG20359.1| (AE005109) tyrosyl-tRNA synthetase; TyrS [Halobac... 155 7e-37
gi|6321624 tyrosyl-tRNA synthetase, cytoplasmic; Tys1p [Saccharo... 149 6e-35
gi|4507947 tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase; tyr... 142 7e-33
sp|P54577|SYY_HUMAN TYROSYL-TRNA SYNTHETASE (TYROSYL--TRNA LIGAS... 142 7e-33
gb|AAC82467.1| (AF087021) tyrosyl-tRNA synthetase; tyrosine--tRN... 141 2e-32
gb|AAF49462.1| (AE003527) CG4561 gene product [Drosophila melano... 136 4e-31
sp|O14055|SYYC_SCHPO TYROSYL-TRNA SYNTHETASE, CYTOPLASMIC (TYROS... 120 2e-26
prf||2122232A Tyr-tRNA synthetase [Pneumocystis carinii] 110 3e-23
emb|CAB60885.2| (AL132880) predicted using Genefinder; prelimina... 92 1e-17
>pir||B75072 tyrosyl-tRNA synthetase (tyrs) PAB1728 - Pyrococcus abyssi (strain
Orsay) >gi|5458391|emb|CAB49879.1| (AJ248286)
tyrosyl-tRNA synthetase (tyrS) [Pyrococcus abyssi]
Length = 375
Score = 764 bits (1951), Expect = 0.0
Identities = 375/375 (100%), Positives = 375/375 (100%)
Query: 1 MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60
MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD
Sbjct: 1 MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60
Query: 61 FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL 120
FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL
Sbjct: 61 FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL 120
Query: 121 ASEILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQG 180
ASEILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQG
Sbjct: 121 ASEILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQG 180
Query: 181 VTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSE 240
VTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSE
Sbjct: 181 VTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSE 240
Query: 241 EQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFRE 300
EQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFRE
Sbjct: 241 EQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFRE 300
Query: 301 EPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYFER 360
EPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYFER
Sbjct: 301 EPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYFER 360
Query: 361 HPEPLELMRSVKITR 375
HPEPLELMRSVKITR
Sbjct: 361 HPEPLELMRSVKITR 375
>pir||F71093 tyrosine--tRNA ligase (EC 6.1.1.1) - Pyrococcus horikoshii
>gi|3257425|dbj|BAA30108.1| (AP000004) 375aa long
hypothetical tyrosyl-tRNA synthetase [Pyrococcus
horikoshii]
Length = 375
Score = 735 bits (1876), Expect = 0.0
Identities = 356/375 (94%), Positives = 367/375 (96%)
Query: 1 MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60
MDIEERINLVLKKPTEEVLTVENLRHLFE+GAPLQHYIGFEISGYIHLGTGLMAGAKIAD
Sbjct: 1 MDIEERINLVLKKPTEEVLTVENLRHLFEIGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60
Query: 61 FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL 120
FQKAGIKTR+FLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL
Sbjct: 61 FQKAGIKTRVFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL 120
Query: 121 ASEILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQG 180
ASEILE GDYWQTVIDISKNVTLSRVMRSITIMGRQMGE+IDFAKLIYPMMQVADIFYQG
Sbjct: 121 ASEILEKGDYWQTVIDISKNVTLSRVMRSITIMGRQMGEAIDFAKLIYPMMQVADIFYQG 180
Query: 181 VTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSE 240
VTIAHAGMDQRKAHVIAIEVAQKL+YHPIVH GEKLKPVAVHHHLLLGLQEPP WPI SE
Sbjct: 181 VTIAHAGMDQRKAHVIAIEVAQKLRYHPIVHEGEKLKPVAVHHHLLLGLQEPPKWPIESE 240
Query: 241 EQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFRE 300
E+FKEIKAQMKMSKSKPYSAVFIHDSPEEI+QKLRKAFCPAREV YNPVLDW E+IIFRE
Sbjct: 241 EEFKEIKAQMKMSKSKPYSAVFIHDSPEEIRQKLRKAFCPAREVRYNPVLDWVEYIIFRE 300
Query: 301 EPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYFER 360
EPTEFT+HRPAKFGGDVTYTTFEELK+DFAEGKLHPLDLKNAVAEYLI LL+PIR YFE+
Sbjct: 301 EPTEFTVHRPAKFGGDVTYTTFEELKRDFAEGKLHPLDLKNAVAEYLINLLEPIRRYFEK 360
Query: 361 HPEPLELMRSVKITR 375
HPEPLELMRSVKITR
Sbjct: 361 HPEPLELMRSVKITR 375
>pir||E72512 probable tyrosyl-tRNA synthetase APE2074 - Aeropyrum pernix
(strain K1) >gi|5105773|dbj|BAA81085.1| (AP000063) 364aa
long hypothetical tyrosyl-tRNA synthetase [Aeropyrum
pernix]
Length = 364
Score = 304 bits (771), Expect = 9e-82
Identities = 167/378 (44%), Positives = 251/378 (66%), Gaps = 20/378 (5%)
Query: 1 MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60
+D+EER N + + T E++T E L+ L GA ++ YIG+E SG H+G L+ K+ D
Sbjct: 4 VDVEERFNRIARN-TVEIVTEEELKGLLASGARIKGYIGYEPSGVAHIGW-LVWMYKVKD 61
Query: 61 FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL 120
+AG+ + A WH++INDKLGGD+++I+ A +V +E G ++V FV
Sbjct: 62 LVEAGVDFSVLEATWHAYINDKLGGDMDLIRAAARIVRRV-----MEAAGVPVERVRFVD 116
Query: 121 ASEILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGES-IDFAKLIYPMMQVADIFYQ 179
A E+ + DYW VI ++K +L+RV R++TIMGR+ E+ +D +KLIYP+MQV+DIFY
Sbjct: 117 AEELASDKDYWGLVIRVAKRASLARVRRALTIMGRRAEEAEVDASKLIYPLMQVSDIFYM 176
Query: 180 GVTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITS 239
+ IA GMDQRKAH++A +VA+KL G K KPVA+H ++ LQ P S
Sbjct: 177 DLDIALGGMDQRKAHMLARDVAEKL--------GRK-KPVAIHTPIISSLQGPGRME-AS 226
Query: 240 EEQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFR 299
+ + ++ A++KMSKSKP +AVF+ DS ++I++K+RKA+CPA++V NPVL+ A +I+F
Sbjct: 227 QGEIDDVLAEVKMSKSKPETAVFVVDSDDDIRRKIRKAYCPAKQVQGNPVLEIARYILFA 286
Query: 300 EEPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYFE 359
+ + RPAK+GG V YT++EEL++D+ +G+LHPLDLKNAVAE LIE+++PIR
Sbjct: 287 RDGFTLRVDRPAKYGGPVEYTSYEELERDYTDGRLHPLDLKNAVAESLIEVVRPIRGAVL 346
Query: 360 RHPEPLELMRSV--KITR 375
P + ++ K+TR
Sbjct: 347 GDPAMKRALEAIEGKVTR 364
>gb|AAK40439.1| Tyrosyl-tRNA synthetase (tyrS) [Sulfolobus solfataricus]
Length = 366
Score = 281 bits (712), Expect = 8e-75
Identities = 157/375 (41%), Positives = 237/375 (62%), Gaps = 24/375 (6%)
Query: 1 MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60
M I++R+ L+++ T EV+T++ LR E L+ YIGFE SG H+G L+ K+ D
Sbjct: 6 MSIDQRLQLIMRN-TAEVITIDELRKKLESDEKLKGYIGFEPSGLFHIGW-LIWTQKVKD 63
Query: 61 FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVM---GGDPKKVE 117
+AGI + A WH+WINDKLGGD+ +I K+ + ++EV+ G D K+
Sbjct: 64 LVEAGINMTLLRAAWHAWINDKLGGDMNLI--------KMAADYAVEVIKNYGVDVGKLN 115
Query: 118 FVLASEILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGES-IDFAKLIYPMMQVADI 176
V A +I++ DYW VI ++KN +L+R+ R++TIMGR+ E+ ID +KLIYP MQV+DI
Sbjct: 116 IVDADDIVKEKDYWALVIKVAKNASLARIKRALTIMGRRAEEAEIDASKLIYPAMQVSDI 175
Query: 177 FYQGVTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWP 236
FY + IA G DQRKAH++A +VA+K+ K K V++H LL+GLQ
Sbjct: 176 FYLDLDIALGGTDQRKAHMLARDVAEKMG---------KKKIVSIHTPLLVGLQGGQRMN 226
Query: 237 ITSEEQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHI 296
IT + +I+A++KMSKSKP SA+F++DS E++++K+ A+CP NP+L ++I
Sbjct: 227 ITEGMEEDDIQAEIKMSKSKPESAIFVNDSREDVERKIMGAYCPKGVAENNPILQILKYI 286
Query: 297 IFREEPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIRE 356
IF I R K+GGDV + +EEL++ + EGK+HP+DLK A L E+L+PIR+
Sbjct: 287 IF-PRYNFVKIERDIKYGGDVEFKDYEELERTYIEGKIHPMDLKKTTARKLNEILEPIRK 345
Query: 357 YFERHPEPLELMRSV 371
E+ PE E+++ +
Sbjct: 346 SLEKKPEFEEMIQKI 360
>sp|P95982|SYY_SULSO TYROSYL-TRNA SYNTHETASE (TYROSINE--TRNA LIGASE) (TYRRS)
>gi|7450987|pir||S75410 tyrosine--tRNA ligase (EC
6.1.1.1) - Sulfolobus solfataricus
>gi|1707816|emb|CAA69524.1| (Y08257) tyrosyl tRNA
synthetase [Sulfolobus solfataricus]
Length = 366
Score = 281 bits (712), Expect = 8e-75
Identities = 157/375 (41%), Positives = 237/375 (62%), Gaps = 24/375 (6%)
Query: 1 MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60
M I++R+ L+++ T EV+T++ LR E L+ YIGFE SG H+G L+ K+ D
Sbjct: 6 MSIDQRLQLIMRN-TAEVITIDELRKKLESDEKLKGYIGFEPSGLFHIGW-LIWTQKVKD 63
Query: 61 FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVM---GGDPKKVE 117
+AGI + A WH+WINDKLGGD+ +I K+ + ++EV+ G D K+
Sbjct: 64 LVEAGINMTLLRAAWHAWINDKLGGDMNLI--------KMAADYAVEVIKNYGVDVGKLN 115
Query: 118 FVLASEILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGES-IDFAKLIYPMMQVADI 176
V A +I++ DYW VI ++KN +L+R+ R++TIMGR+ E+ ID +KLIYP MQV+DI
Sbjct: 116 IVDADDIVKEKDYWALVIKVAKNASLARIKRALTIMGRRAEEAEIDASKLIYPAMQVSDI 175
Query: 177 FYQGVTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWP 236
FY + IA G DQRKAH++A +VA+K+ K K V++H LL+GLQ
Sbjct: 176 FYLDLDIALGGTDQRKAHMLARDVAEKMG---------KKKIVSIHTPLLVGLQGGQRMN 226
Query: 237 ITSEEQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHI 296
IT + +I+A++KMSKSKP SA+F++DS E++++K+ A+CP NP+L ++I
Sbjct: 227 ITEGMEEDDIQAEIKMSKSKPESAIFVNDSREDVERKIMGAYCPKGVAENNPILQILKYI 286
Query: 297 IFREEPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIRE 356
IF I R K+GGDV + +EEL++ + EGK+HP+DLK A L E+L+PIR+
Sbjct: 287 IF-PRYNFVKIERDIKYGGDVEFKDYEELERTYIEGKIHPMDLKKTTARKLNEILEPIRK 345
Query: 357 YFERHPEPLELMRSV 371
E+ PE E+++ +
Sbjct: 346 SLEKKPEFEEMIQKI 360
>pir||T03741 probable tyrosine--tRNA ligase (EC 6.1.1.1) - common tobacco
>gi|1841468|emb|CAA71881.1| (Y10990) Tyrosyl-tRNA
synthetase [Nicotiana tabacum]
Length = 408
Score = 224 bits (564), Expect = 2e-57
Identities = 127/374 (33%), Positives = 206/374 (54%), Gaps = 31/374 (8%)
Query: 1 MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60
M +EE+ +V + EE + + L +L Y GFE SG +H+ G++ +
Sbjct: 58 MSLEEKFKIV-RSIGEECIQEDELMNLLAKKPQPVCYDGFEPSGRMHIAQGVLKALNVNK 116
Query: 61 FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL 120
AG K +I++ADW + +N+K+GGDL+ I+ V ++ + + GG VEF+
Sbjct: 117 LTSAGCKVKIWIADWFAQLNNKMGGDLKKIEVVGQYLIEIWKAVGMNLEGGH---VEFLW 173
Query: 121 ASEILENG--DYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFY 178
+S+ + + +YW V+D+++ L R++R IMGR + + A++ YP MQ ADIF+
Sbjct: 174 SSKEINSRAHEYWPLVMDVARRNKLPRILRCCQIMGRSEQDELTAAQIFYPCMQCADIFF 233
Query: 179 QGVTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPIT 238
I GMDQRK +V+A E ++ K KP+ + HH+L GLQE
Sbjct: 234 LKADICQLGMDQRKVNVLAREYCDDIR--------RKNKPIILSHHMLPGLQE------- 278
Query: 239 SEEQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIF 298
Q KMSKS P S++++ D ++ K++KAFCP + V NP L++ ++I+
Sbjct: 279 ---------GQEKMSKSDPSSSIYMEDEEADVNLKIKKAFCPPKVVEKNPCLEYIKYIVL 329
Query: 299 REEPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYF 358
EF I R A+ G D TY FEEL D+ G LHP DLK A+++ + ++L+P+R++F
Sbjct: 330 -PWFNEFKIERSAENGADKTYKNFEELAADYESGNLHPADLKPALSKAINKILQPVRDHF 388
Query: 359 ERHPEPLELMRSVK 372
+ + +LM+ VK
Sbjct: 389 KNDQKAKDLMKRVK 402
>gb|AAC69137.1| (U78721) putative tyrosyl-tRNA synthetase [Arabidopsis thaliana]
Length = 460
Score = 216 bits (544), Expect = 4e-55
Identities = 127/355 (35%), Positives = 200/355 (55%), Gaps = 33/355 (9%)
Query: 2 DIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIADF 61
++E+R +V + EE + E L++L A Y GFE SG +H+ G+M +
Sbjct: 4 EVEKRYKIV-RSIGEECIQEEELKNLLAKKAAPICYDGFEPSGRMHIAQGVMKVINVNKM 62
Query: 62 QKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLA 121
AG + +I++ADW + +N+K+GGDL+ I+ V +YF ++ + G D KVEF+ +
Sbjct: 63 TSAGCRVKIWIADWFAQLNNKMGGDLKKIRVVG-EYF----QEIWKAAGMDNDKVEFLWS 117
Query: 122 SEILEN--GDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQ 179
SE + + YW V+DI++ L R++R + IMGR + + A+++YP MQ ADIF+
Sbjct: 118 SEEINSKADKYWPLVMDIARKNKLPRILRCVQIMGRSETDELSAAQILYPCMQCADIFFL 177
Query: 180 GVTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITS 239
I GMDQRK +V+A E +K K KP+ + HH+L GLQ+
Sbjct: 178 EADICQLGMDQRKVNVLAREYCDDIK--------RKNKPIILSHHMLPGLQQ-------- 221
Query: 240 EEQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFR 299
Q KMSKS P SA+F+ D E+ K++KA+CP + V NP L++ ++II
Sbjct: 222 --------GQEKMSKSDPLSAIFMEDEEAEVNVKIKKAYCPPKVVKGNPCLEYIKYIIL- 272
Query: 300 EEPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPI 354
EFT+ R ++GG+ TY +FE++ D+ G+LHP DLK + L ++L+ I
Sbjct: 273 PWFDEFTVERNEEYGGNKTYKSFEDIAADYESGELHPGDLKKGLMNALNKILQVI 327
>gi|11498382 tyrosyl-tRNA synthetase (tyrS) [Archaeoglobus fulgidus]
>gi|3122912|sp|O29482|SYY_ARCFU TYROSYL-TRNA SYNTHETASE
(TYROSINE--TRNA LIGASE) (TYRRS) >gi|7450986|pir||H69346
tyrosyl-tRNA synthetase (tyrS) homolog - Archaeoglobus
fulgidus >gi|2649832|gb|AAB90462.1| (AE001051)
tyrosyl-tRNA synthetase (tyrS) [Archaeoglobus fulgidus]
Length = 323
Score = 213 bits (538), Expect = 2e-54
Identities = 142/357 (39%), Positives = 205/357 (56%), Gaps = 41/357 (11%)
Query: 1 MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60
MDI E++ L+ + EEV+T E LR L E + Y+G+E SG IHLG +M K+ D
Sbjct: 1 MDITEKLRLITRN-AEEVVTEEELRQLIETKEKPRAYVGYEPSGEIHLGH-MMTVQKLMD 58
Query: 61 FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL 120
Q+AG + + LAD H+++N+K G E I EVA Y K K +G D + +FVL
Sbjct: 59 LQEAGFEIIVLLADIHAYLNEK--GTFEEIAEVA-DYNK----KVFIALGLDESRAKFVL 111
Query: 121 ASEILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQG 180
SE + DY V+ +++ TL+R RS+ + R+ + + +++IYP+MQ DI + G
Sbjct: 112 GSEYQLSRDYVLDVLKMARITTLNRARRSMDEVSRRKEDPM-VSQMIYPLMQALDIAHLG 170
Query: 181 VTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSE 240
V +A G+DQRK H++A E +L Y PV +H +L+GL
Sbjct: 171 VDLAVGGIDQRKIHMLARENLPRLGYS---------SPVCLHTPILVGLDG--------- 212
Query: 241 EQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAE-HIIFR 299
KMS SK + + + D PEE+++K+RKA+CPA V NP+LD A+ HI+ R
Sbjct: 213 ---------QKMSSSKG-NYISVRDPPEEVERKIRKAYCPAGVVEENPILDIAKYHILPR 262
Query: 300 EEPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIRE 356
+ + R AKFGGDV Y +FEEL +DF G+LHPLDLK AVA+YL LL+ R+
Sbjct: 263 FG--KIVVERDAKFGGDVEYASFEELAEDFKSGQLHPLDLKIAVAKYLNMLLEDARK 317
>gb|AAF16759.1|AC010155_12 (AC010155) F3M18.22 [Arabidopsis thaliana]
Length = 895
Score = 206 bits (518), Expect = 4e-52
Identities = 130/404 (32%), Positives = 215/404 (53%), Gaps = 61/404 (15%)
Query: 2 DIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGT----------- 50
++E+R N+V + E+ + + L+ L A Y GFE SG +H+
Sbjct: 24 EVEKRYNVV-RSVGEQCIHDDELKDLLAKKAAPVCYDGFEPSGRMHIAQLALEFFYVLSS 82
Query: 51 -----------------GLMAGAKIADFQKAGIKTRIFLADWHSWINDKLGGDLEVIQEV 93
GLM + AG + +I++ADW +++N+KLGGDL+ I+ V
Sbjct: 83 LSEKLLLARLTLLLPWQGLMKIMNVNKLTSAGCRVKIWIADWFAYMNNKLGGDLKKIRVV 142
Query: 94 ALKYFKVGMEKSIEVMGGDPKKVEFVLAS-EILENGD-YWQTVIDISKNVTLSRVMRSIT 151
+YFK + + G + + VEF+ +S EI GD YW V+DI+ +L+++ R +
Sbjct: 143 G-EYFK----EIFQAAGMNSENVEFLWSSDEINAKGDEYWPLVMDIACRNSLAQIKRCMP 197
Query: 152 IMGRQMGESIDFAKLIYPMMQVADIFYQGVTIAHAGMDQRKAHVIAIEVAQKLKYHPIVH 211
IMG E + A ++Y MQ AD F+ I GMDQ+ +++A + +K
Sbjct: 198 IMGLSENEELSAAHILYVCMQCADTFFLEADICQLGMDQQTVNLLARDYCDVVK------ 251
Query: 212 NGEKLKPVAVHHHLLLGLQEPPVWPITSEEQFKEIKAQMKMSKSKPYSAVFIHDSPEEIK 271
+ KPV + HH+L GLQ+ Q KMSKS P SA+F+ D E+
Sbjct: 252 --RENKPVILSHHMLPGLQQ----------------GQKKMSKSDPSSAIFMEDEEAEVN 293
Query: 272 QKLRKAFCPAREVNYNPVLDWAEHIIFREEPTEFTIHRPAKFGGDVTYTTFEELKKDFAE 331
K++KA+CP V NP L++ +HII +EFT+ R K+GG+ T+ +FE++ D+
Sbjct: 294 VKIKKAYCPPDIVEGNPCLEYVKHIILPWF-SEFTVERDEKYGGNRTFKSFEDITTDYES 352
Query: 332 GKLHPLDLKNAVAEYLIELLKPIREYFERHPEPLELMRSVKITR 375
G+LHP DLK+A+++ L ++L+P+R++F+ + L++ VK+ +
Sbjct: 353 GQLHPKDLKDALSKALNKILQPVRDHFKTNSRAKNLLKQVKVIK 396
Score = 196 bits (493), Expect = 4e-49
Identities = 119/340 (35%), Positives = 186/340 (54%), Gaps = 33/340 (9%)
Query: 10 VLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIADFQKAGIKTR 69
+++ EE + + L++L Y GFE SG +H+ G+M + AG + +
Sbjct: 485 IVRSIGEECIQEDELKNLLAKKPAPICYDGFEPSGRMHIAQGVMKVTNVNKLTSAGCQVK 544
Query: 70 IFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLASEIL--EN 127
I++ADW + +N+KLGGDLE I+ V +YFK + + G + KVEF+ AS+ + +
Sbjct: 545 IWIADWFAQLNNKLGGDLERIRVVG-EYFK----EIWQAGGMNNDKVEFLWASDEINGKG 599
Query: 128 GDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQGVTIAHAG 187
YW V+DI++ L R++R IMGR E + A+++YP MQ ADIF I G
Sbjct: 600 SKYWPLVMDIARRNNLRRILRCGQIMGRSETEVLSAAQILYPCMQCADIFLLEADICQLG 659
Query: 188 MDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQFKEIK 247
MDQRK +++A E +K K KP+ + HH+L GLQ+
Sbjct: 660 MDQRKVNMLAREYCADIK--------RKNKPIILSHHMLPGLQQ---------------- 695
Query: 248 AQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFREEPTEFTI 307
Q KMSKS P SA+F+ D ++ +K+ KA+CP + V NP L++ ++I+ EF +
Sbjct: 696 GQEKMSKSDPSSAIFMEDEEADVNEKISKAYCPPKTVEGNPCLEYVKYIVL-PRFNEFKV 754
Query: 308 HRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYL 347
K GG+ T+ +FE++ D+ G+LHP DLK A+ + L
Sbjct: 755 -ESEKNGGNKTFNSFEDIVADYETGELHPEDLKKALMKAL 793
>sp|Q57834|SYY_METJA TYROSYL-TRNA SYNTHETASE (TYROSINE--TRNA LIGASE) (TYRRS)
>gi|2129341|pir||E64348 tyrosine--tRNA ligase (EC
6.1.1.1) - Methanococcus jannaschii
>gi|1591094|gb|AAB98375.1| (U67491) tyrosyl-tRNA
synthetase (trS) [Methanococcus jannaschii]
Length = 306
Score = 200 bits (503), Expect = 2e-50
Identities = 136/347 (39%), Positives = 197/347 (56%), Gaps = 48/347 (13%)
Query: 10 VLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIADFQKAGIKTR 69
++K+ T E+++ E LR + + YIGFE SG IHLG L K+ D Q AG
Sbjct: 6 MIKRNTSEIISEEELREVLKKDEK-SAYIGFEPSGKIHLGHYLQI-KKMIDLQNAGFDII 63
Query: 70 IFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLASEILENGD 129
I LAD H+++N K G+L+ I+++ Y K K E MG K ++V SE + D
Sbjct: 64 ILLADLHAYLNQK--GELDEIRKIG-DYNK----KVFEAMG---LKAKYVYGSEFQLDKD 113
Query: 130 YWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQGVTIAHAGMD 189
Y V ++ TL R RS+ ++ R+ E+ A++IYP+MQV DI Y GV +A GM+
Sbjct: 114 YTLNVYRLALKTTLKRARRSMELIARE-DENPKVAEVIYPIMQVNDIHYLGVDVAVGGME 172
Query: 190 QRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQFKEIKAQ 249
QRK H++A E+ K K V +H+ +L GL +
Sbjct: 173 QRKIHMLARELLPK-------------KVVCIHNPVLTGLD-----------------GE 202
Query: 250 MKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFREEPTEFTIHR 309
KMS SK + + + DSPEEI+ K++KA+CPA V NP+++ A++ F E P TI R
Sbjct: 203 GKMSSSKG-NFIAVDDSPEEIRAKIKKAYCPAGVVEGNPIMEIAKY--FLEYP--LTIKR 257
Query: 310 PAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIRE 356
P KFGGD+T ++EEL+ F +LHP+DLKNAVAE LI++L+PIR+
Sbjct: 258 PEKFGGDLTVNSYEELESLFKNKELHPMDLKNAVAEELIKILEPIRK 304
>emb|CAC11652.1| (AL445064) probable tyrosyl-tRNA synthetase [Thermoplasma
acidophilum]
Length = 332
Score = 196 bits (494), Expect = 3e-49
Identities = 126/352 (35%), Positives = 196/352 (54%), Gaps = 41/352 (11%)
Query: 13 KPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIADFQKAGIKTRIFL 72
K T EV+T E+ L E + ++ YIG E SG H+ T +M K+A+ Q IK + L
Sbjct: 9 KNTREVVTREDAERL-EGKSDIKSYIGIEPSGIPHIATAVMWPRKLAEIQD-DIKVTVLL 66
Query: 73 ADWHSWINDKLGGDLEVIQ---EVALKYFKV-GMEKSIEVMGGDPKKVEFVLASEILENG 128
ADWH+ IN+KL GDL++I+ E+ K F+ G+ K+ ++V AS+++++
Sbjct: 67 ADWHAMINNKLHGDLDLIRKGGEILRKTFQAEGLTKA-----------DYVWASDLVDSS 115
Query: 129 DYWQTVIDISKNVTLSRVMRSITIMGRQMGESI-DFAKLIYPMMQVADIFYQGVTIAHAG 187
+YW+ ID +K TL RV+RS+ IMGR ++ DF+ +YP+MQV DIFY V +A G
Sbjct: 116 EYWRMFIDTAKRSTLKRVIRSLPIMGRNETDAEKDFSMYLYPIMQVTDIFYLDVDMAFGG 175
Query: 188 MDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQFKEIK 247
MDQR AH++A ++A+K+K + K V+VH LL L+ +
Sbjct: 176 MDQRHAHMLARDIAEKMK---------RKKVVSVHGFLLSSLKGN-----------ARMD 215
Query: 248 AQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFREEPTEFTI 307
+KMSKS P SA+ + D E+I++K+ A+CP ++V NPV + ++II I
Sbjct: 216 NFVKMSKSDPNSAILVTDHMEDIERKINAAYCPPQQVEGNPVAEIMKYIIIPYYGKSIEI 275
Query: 308 HRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYFE 359
H G + + E + + G++ P DLK+ VA L E+++P R E
Sbjct: 276 HGS---NGVINLDSVENFDQAYQRGEIQPADLKHKVATILNEMVEPARRSLE 324
>sp|O27795|SYY_METTH TYROSYL-TRNA SYNTHETASE (TYROSINE--TRNA LIGASE) (TYRRS)
>gi|7450985|pir||H69102 tyrosine--tRNA ligase (EC
6.1.1.1) - Methanobacterium thermoautotrophicum (strain
Delta H) >gi|2622897|gb|AAB86233.1| (AE000932)
tyrosyl-tRNA synthetase [Methanobacterium
thermoautotrophicum]
Length = 319
Score = 191 bits (480), Expect = 1e-47
Identities = 123/343 (35%), Positives = 190/343 (54%), Gaps = 39/343 (11%)
Query: 17 EVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIADFQKAGIKTRIFLADWH 76
EV+T E L + + P+ Y G+E SG IHLG L K+ + Q AG + +I LAD+H
Sbjct: 14 EVITPEELMDVLKKDEPVV-YTGYEPSGRIHLGHALTV-RKLRELQDAGFRVKILLADYH 71
Query: 77 SWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLASEILENGDYWQTVID 136
+++N K G +E I+E+A Y +K +G P++ EF+L S +Y V
Sbjct: 72 AYLNGK--GSMERIRELA-DY----NQKCFLALGLSPERTEFILGSSFQTEPEYTDLVYR 124
Query: 137 ISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQGVTIAHAGMDQRKAHVI 196
++ TL R RS+ + R+ + A++IYP+MQV D+ Y GV +A GM+QRK H++
Sbjct: 125 LALITTLLRAKRSMAQITRESRDH-KVAEVIYPLMQVIDMVYLGVDVALGGMEQRKIHML 183
Query: 197 AIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQFKEIKAQMKMSKSK 256
A E +L + PV +H LL G KMS SK
Sbjct: 184 ARENLPRLGFDA---------PVCIHTPLLHGTD-----------------GSEKMSSSK 217
Query: 257 PYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFREEPTEFTIHRPAKFGGD 316
+ + + DSP+EI++K++K++CP E NP+++ ++ I E TI RP KFGGD
Sbjct: 218 G-NFIAVDDSPDEIREKVKKSYCPMGETEGNPIIEIVKYFIMPEYGM-MTIRRPEKFGGD 275
Query: 317 VTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYFE 359
+ +EL + ++ +LHPLDLKNAV++YL+++L+P+REY E
Sbjct: 276 LELE-LDELLEMYSSSELHPLDLKNAVSDYLVDMLEPVREYME 317
>emb|CAB94018.1| (AL358652) tyrosyl-tRNA synthetase isolog [Leishmania major]
Length = 682
Score = 190 bits (479), Expect = 2e-47
Identities = 125/392 (31%), Positives = 205/392 (51%), Gaps = 55/392 (14%)
Query: 1 MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60
M+ +ER L L+ EE + LR+L E ++ Y GFE SG +H+ G+ +
Sbjct: 1 MNTDERYKL-LRSVGEECIQESELRNLIEKKPLIRCYDGFEPSGRMHIAQGIFKAVNVNK 59
Query: 61 FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL 120
AG + ++ADW + +NDK+GG+LE I+ V +V + G D KV F+
Sbjct: 60 CTAAGCEFVFWVADWFALMNDKVGGELEKIRIVGRYLIEVW-----KAAGMDMDKVLFLW 114
Query: 121 AS-EILENGD-YWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFY 178
+S EI + D YW+ V+DI + T++R+ + TIMG+ G ++ A+++YP+MQ DIF+
Sbjct: 115 SSEEITSHADTYWRMVLDIGRQNTIARIKKCCTIMGKTEG-TLTAAQVLYPLMQCCDIFF 173
Query: 179 QGVTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPIT 238
I G+DQRK +++A E + G KLKPV + HH+L GL++
Sbjct: 174 LKADICQLGLDQRKVNMLAREYCDLI--------GRKLKPVILSHHMLAGLKQ------- 218
Query: 239 SEEQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFC---------------PARE 283
Q KMSKS P SA+F+ D+ E++ +K+R+A+C P
Sbjct: 219 ---------GQAKMSKSDPDSAIFMEDTEEDVARKIRQAYCPRVKQSASAITDDGAPVAT 269
Query: 284 VNYNPVLDWAEHIIFREEPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAV 343
+ NPVLD+ + +++ TI TY T+E+L++ F ++ LK+ +
Sbjct: 270 DDRNPVLDYFQCVVYARPGAAATI-------DGTTYATYEDLEQAFVSDEVSEDALKSCL 322
Query: 344 AEYLIELLKPIREYFERHPEPLELMRSVKITR 375
+ + LL+P+R++F + E EL+ +VK R
Sbjct: 323 IDEVNALLEPVRQHFASNEEAHELLEAVKSYR 354
>gb|AAG20359.1| (AE005109) tyrosyl-tRNA synthetase; TyrS [Halobacterium sp. NRC-1]
Length = 327
Score = 155 bits (388), Expect = 7e-37
Identities = 116/360 (32%), Positives = 181/360 (50%), Gaps = 45/360 (12%)
Query: 1 MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60
M+ ERI + T EV+T E +R L E + Y+G+E SG +HLG L+ K+ D
Sbjct: 1 MNAYERIT----RNTAEVVTEEEVRELAEDPEGKRVYVGYEPSGVLHLGH-LLTANKLMD 55
Query: 61 FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL 120
Q AG++ + LAD H+++NDK G E I+ A + M+ G D + EFVL
Sbjct: 56 LQDAGMEVVVLLADVHAYLNDK--GSFEEIRATADQ-----MKAQFLAYGLDEDQTEFVL 108
Query: 121 ASEILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQG 180
S + DY + + +L R R++ + Q GE+ + ++YP+MQ DI Y
Sbjct: 109 GSSFQLDEDYELDLHAMQVETSLKRAQRAMAEI--QSGETPKVSHVVYPLMQALDIEYLD 166
Query: 181 VTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSE 240
+ +A GMDQRK H++A E + Y +PV L P + + S
Sbjct: 167 LDLAIGGMDQRKVHMLAREELPSVGYEK--------RPV---------LHTPIIGDLGSG 209
Query: 241 EQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPARE----VNYNPVLDWAEHI 296
+ KMS S+ + + + DS +I++K+ AFCP NPVL+ ++
Sbjct: 210 DG--------KMSSSEGVT-ISMEDSTADIEEKVTGAFCPQTRDPEGETVNPVLELFQYH 260
Query: 297 IFREEPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIRE 356
+F E + RP ++GGD+ Y ++E+L D G+LHP D K A+A L EL++P R+
Sbjct: 261 VFPRFD-EVVVQRPDEYGGDLVYESYEDLADDLESGELHPADAKGALAAALDELIEPGRQ 319
>gi|6321624 tyrosyl-tRNA synthetase, cytoplasmic; Tys1p [Saccharomyces
cerevisiae] >gi|549037|sp|P36421|SYYC_YEAST TYROSYL-TRNA
SYNTHETASE, CYTOPLASMIC (TYROSYL--TRNA LIGASE) (TYRRS)
>gi|539380|pir||A45999 tyrosine--tRNA ligase (EC
6.1.1.1) [validated] - yeast (Saccharomyces cerevisiae)
>gi|173120|gb|AAB59329.1| (L12221) tyrosyl-tRNA
synthetase [Saccharomyces cerevisiae]
>gi|1323328|emb|CAA97211.1| (Z72970) ORF YGR185c
[Saccharomyces cerevisiae] >gi|1430951|emb|CAA67529.1|
(X99074) G7522 [Saccharomyces cerevisiae]
Length = 394
Score = 149 bits (372), Expect = 6e-35
Identities = 115/371 (30%), Positives = 181/371 (47%), Gaps = 39/371 (10%)
Query: 1 MDIEERINLVLKKPTEEVLTVENLRHLFEVGAP-LQHYIGFEISGYIHLGTGLMAGAKIA 59
+D E L+ K +EVL + ++ + EV L+ Y G +G H G + K+A
Sbjct: 7 VDPNEAFGLITKN-LQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGY-FVPMTKLA 64
Query: 60 DFQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFV 119
DF KAG + + LAD H+++ D + LEV+ A KY+++ ++ + + +K++FV
Sbjct: 65 DFLKAGCEVTVLLADLHAFL-DNMKAPLEVVNYRA-KYYELTIKAILRSINVPIEKLKFV 122
Query: 120 LASEILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQ 179
+ S DY + +S V+ + R+ + +Q+ + + LIYP+MQ D +
Sbjct: 123 VGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPL-LSGLIYPLMQALDEQFL 181
Query: 180 GVTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITS 239
V G+DQRK V+A E L Y H + P GL +
Sbjct: 182 DVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVP---------GLAQGG------ 226
Query: 240 EEQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHII-- 297
KMS S P S + + + P+++K+K+ AFC V N +L + +++I
Sbjct: 227 -----------KMSASDPNSKIDLLEEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAP 275
Query: 298 -----FREEPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLK 352
F EF I RP KFGG +TY +FEE+K F E KL P DLK VA+ + ELL+
Sbjct: 276 IQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLE 335
Query: 353 PIREYFERHPE 363
PIR+ F + E
Sbjct: 336 PIRQEFANNKE 346
>gi|4507947 tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase; tyrosyl tRNA
ligase [Homo sapiens] >gi|2665519|gb|AAB88409.1|
(U89436) tyrosyl-tRNA synthetase [Homo sapiens]
Length = 528
Score = 142 bits (354), Expect = 7e-33
Identities = 110/355 (30%), Positives = 181/355 (50%), Gaps = 34/355 (9%)
Query: 4 EERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIADFQK 63
EE+++L+ + +EVL E L+ + + L+ Y G +G H+ + +KIADF K
Sbjct: 8 EEKLHLITRN-LQEVLGEEKLKEILKE-RELKIYWGTATTGKPHVAY-FVPMSKIADFLK 64
Query: 64 AGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLASE 123
AG + I AD H+++ D + E++ E+ + Y++ ++ +E +G +K++F+ ++
Sbjct: 65 AGCEVTILFADLHAYL-DNMKAPWELL-ELRVSYYENVIKAMLESIGVPLEKLKFIKGTD 122
Query: 124 ILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQGVTI 183
+ +Y V +S VT ++ + +Q+ + + L+YP +Q D Y V
Sbjct: 123 YQLSKEYTLDVYRLSSVVTQHDSKKAGAEVVKQVEHPL-LSGLLYPGLQALDEEYLKVDA 181
Query: 184 AHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQF 243
G+DQRK A + L Y VH L P V +T
Sbjct: 182 QFGGIDQRKIFTFAEKYLPALGYSKRVH-----------------LMNPMVPGLTGS--- 221
Query: 244 KEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFREEPT 303
KMS S+ S + + D E++K+KL+KAFC V N VL + +H++F + +
Sbjct: 222 -------KMSSSEEESKIDLLDRKEDVKKKLKKAFCEPGNVENNGVLSFIKHVLFPLK-S 273
Query: 304 EFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYF 358
EF I R K+GG+ TYT + +L+KDFA +HP DLKN+V L +LL PIRE F
Sbjct: 274 EFVILRDEKWGGNKTYTAYVDLEKDFAAEVVHPGDLKNSVEVALNKLLDPIREKF 328
>sp|P54577|SYY_HUMAN TYROSYL-TRNA SYNTHETASE (TYROSYL--TRNA LIGASE) (TYRRS)
>gi|1184699|gb|AAB39406.1| (U40714) tyrosyl-tRNA
synthetase [Homo sapiens]
Length = 388
Score = 142 bits (354), Expect = 7e-33
Identities = 110/355 (30%), Positives = 181/355 (50%), Gaps = 34/355 (9%)
Query: 4 EERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIADFQK 63
EE+++L+ + +EVL E L+ + + L+ Y G +G H+ + +KIADF K
Sbjct: 8 EEKLHLITRN-LQEVLGEEKLKEILKE-RELKIYWGTATTGKPHVAY-FVPMSKIADFLK 64
Query: 64 AGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLASE 123
AG + I AD H+++ D + E++ E+ + Y++ ++ +E +G +K++F+ ++
Sbjct: 65 AGCEVTILFADLHAYL-DNMKAPWELL-ELRVSYYENVIKAMLESIGVPLEKLKFIKGTD 122
Query: 124 ILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQGVTI 183
+ +Y V +S VT ++ + +Q+ + + L+YP +Q D Y V
Sbjct: 123 YQLSKEYTLDVYRLSSVVTQHDSKKAGAEVVKQVEHPL-LSGLLYPGLQALDEEYLKVDA 181
Query: 184 AHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQF 243
G+DQRK A + L Y VH L P V +T
Sbjct: 182 QFGGIDQRKIFTFAEKYLPALGYSKRVH-----------------LMNPMVPGLTGS--- 221
Query: 244 KEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFREEPT 303
KMS S+ S + + D E++K+KL+KAFC V N VL + +H++F + +
Sbjct: 222 -------KMSSSEEESKIDLLDRKEDVKKKLKKAFCEPGNVENNGVLSFIKHVLFPLK-S 273
Query: 304 EFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYF 358
EF I R K+GG+ TYT + +L+KDFA +HP DLKN+V L +LL PIRE F
Sbjct: 274 EFVILRDEKWGGNKTYTAYVDLEKDFAAEVVHPGDLKNSVEVALNKLLDPIREKF 328
>gb|AAC82467.1| (AF087021) tyrosyl-tRNA synthetase; tyrosine--tRNA ligase [Bos
taurus]
Length = 528
Score = 141 bits (351), Expect = 2e-32
Identities = 109/355 (30%), Positives = 179/355 (49%), Gaps = 34/355 (9%)
Query: 4 EERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIADFQK 63
EE+++L+ + +EVL E L+ + + L+ Y G +G H+ + +KIADF K
Sbjct: 8 EEKLSLITRN-LQEVLGEEKLKEILKE-RELKVYWGTATTGKPHVAY-FVPMSKIADFLK 64
Query: 64 AGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLASE 123
AG + I AD H+++ D + +V+ E+ Y++ ++ +E +G +K+ F+ ++
Sbjct: 65 AGCEVTILFADLHAYL-DNMKAPWDVL-ELRTSYYENVIKAMLESIGVPLEKLRFIKGTD 122
Query: 124 ILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQGVTI 183
+ +Y V +S VT ++ + +Q+ + + L+YP +Q D Y V
Sbjct: 123 YQLSKEYTLDVYRLSSVVTQHDAKKAGAEVVKQVEHPL-LSGLLYPGLQALDEEYLKVDA 181
Query: 184 AHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQF 243
G+DQRK A + L Y +H L P V +T
Sbjct: 182 QFGGVDQRKIFTFAEKYLPALGYSKRIH-----------------LMNPMVPGLTGS--- 221
Query: 244 KEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFREEPT 303
KMS S+ S + + D E++K+KL+KAFC V N VL + H++F + +
Sbjct: 222 -------KMSSSEEESKIDLLDRKEDVKKKLKKAFCEPGNVENNGVLAFIRHVLFPLK-S 273
Query: 304 EFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYF 358
EF I R K+GG+ TYT + +L+KDFA+ +HP DLKN+V L +LL PIRE F
Sbjct: 274 EFVILRDEKWGGNKTYTAYLDLEKDFADEVVHPGDLKNSVEVALNKLLDPIREKF 328
>gb|AAF49462.1| (AE003527) CG4561 gene product [Drosophila melanogaster]
Length = 525
Score = 136 bits (339), Expect = 4e-31
Identities = 102/335 (30%), Positives = 170/335 (50%), Gaps = 40/335 (11%)
Query: 34 LQHYIGFEISGYIHLGTGLMAGAKIADFQKAGIKTRIFLADWHSWINDKLGGDLEVIQEV 93
L+ Y G +G H+ + +KIADF KAG + I AD H+++ D + ++ E+
Sbjct: 35 LKIYWGTATTGKPHVAY-FVPMSKIADFLKAGCEVTILFADLHAYL-DNMKAPWSLL-EL 91
Query: 94 ALKYFKVGMEKSIEVMGGDPKKVEFVLASEILENGDYWQTVIDISKNVTLSRVMRSITIM 153
KY++ ++ + +G +K++FV S+ + +Y V +S VT ++
Sbjct: 92 RTKYYEQVIKAMLSSIGVPLEKLKFVKGSDYQLSKEYTLDVYKLSSVVTQHDAKKA---- 147
Query: 154 GRQMGESIDF---AKLIYPMMQVADIFYQGVTIAHAGMDQRKAHVIAIEVAQKLKYHPIV 210
G ++ + +++ + L+YP +Q D Y V G+DQRK + + +L Y +
Sbjct: 148 GAEVVKQVEYPLLSGLLYPGLQALDEEYLKVDAQFGGVDQRKIFTFSEKYLPQLGYEKRI 207
Query: 211 HNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQFKEIKAQMKMSKSKPYSAVFIHDSPEEI 270
H + P GL A KMS S+ S + + DSP +
Sbjct: 208 HFMNPMVP---------GL------------------AGGKMSSSEEDSKIDLLDSPANV 240
Query: 271 KQKLRKAFCPAREVNYNPVLDWAEHIIFR--EEPTEFTIHRPAKFGGDVTYTTFEELKKD 328
K+KL+KAFC + N +L + +H++F +E F ++R A+ GGDVT+ +E+L+K
Sbjct: 241 KKKLKKAFCEPGNIADNGLLSFVKHVLFSLFKEGEGFEVNREAEHGGDVTFLKYEDLEKY 300
Query: 329 FAEGKLHPLDLKNAVAEYLIELLKPIREYFERHPE 363
+AE KLHP DLK V +Y+ LL PIR+ FE +PE
Sbjct: 301 YAEDKLHPGDLKATVEKYINRLLDPIRKAFE-NPE 334
>sp|O14055|SYYC_SCHPO TYROSYL-TRNA SYNTHETASE, CYTOPLASMIC (TYROSYL--TRNA LIGASE) (TYRRS)
>gi|7493542|pir||T41049 tyrosine--tRNA ligase (EC
6.1.1.1) cytoplasmic - fission yeast
(Schizosaccharomyces pombe) >gi|3451306|emb|CAA20443.1|
(AL031324) tyrosyl-trna synthetase cytoplasmic EC
6.1.1.1 [Schizosaccharomyces pombe]
Length = 401
Score = 120 bits (299), Expect = 2e-26
Identities = 100/365 (27%), Positives = 173/365 (47%), Gaps = 38/365 (10%)
Query: 4 EERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIADFQK 63
+E+ L+ + +EVL + +R + + Y G +G H G + K+ADF K
Sbjct: 6 DEKYELITRN-LQEVLGAKMIREILNE-RDISLYWGSAPTGRPHCGY-FVPMMKLADFLK 62
Query: 64 AGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLASE 123
AG+ + LAD H+++ D + +E++Q ++Y+++ ++ ++ + +K+ FV+ S
Sbjct: 63 AGVHVTVLLADVHAFL-DNMKAPMELVQH-RVRYYEIIVKSILKSLNIPIEKLRFVIGSS 120
Query: 124 ILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQGVTI 183
DY ++ + T R+ + +Q+ + + LIYP MQ D Y GV +
Sbjct: 121 YQLKEDYTLDNFRLAASTTEHTARRAGAEVVKQVASPL-LSSLIYPGMQALDEQYLGVDV 179
Query: 184 AHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQF 243
G+DQRK V+A EV L Y H L P V +
Sbjct: 180 QFGGVDQRKIFVMAEEVLPVLGYKKRGH-----------------LMNPMVPSL------ 216
Query: 244 KEIKAQMKMSKSKPYSA-VFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIF---- 298
A KMS S +A + I D P+ + +K+R AFC V N L + +++ F
Sbjct: 217 ----AGGKMSSSAAANAKIDILDDPKTVNKKIRSAFCEPGVVEENGCLAFLKYVSFPAME 272
Query: 299 REEPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYF 358
TEF I RP +FGG + + T+EE++K + + L P DLK + + LL ++E
Sbjct: 273 LRGETEFVIDRPEQFGGRMVFKTYEEVEKAYKDLTLSPQDLKLGLESSVNTLLAGVQEQL 332
Query: 359 ERHPE 363
+++P+
Sbjct: 333 KQYPD 337
>prf||2122232A Tyr-tRNA synthetase [Pneumocystis carinii]
Length = 370
Score = 110 bits (272), Expect = 3e-23
Identities = 105/364 (28%), Positives = 174/364 (46%), Gaps = 37/364 (10%)
Query: 10 VLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIADFQKAGIKTR 69
++ + +EVL E LR + E L+ Y G +G H G + KIADF KA ++
Sbjct: 14 LITRGLQEVLGAERLRKILEE-RDLKLYWGTSPTGKPHCGY-FVPMIKIADFLKAEVEVT 71
Query: 70 IFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLASEILENGD 129
I AD H+++ D L +++++ A KY++ ++ ++ +G +K+ FVL S +
Sbjct: 72 ILFADIHAFL-DNLKAPIDIVKYRA-KYYEFIIKAILKSIGVSTEKLRFVLGSSYQLSSK 129
Query: 130 YWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQGVTIAHAGMD 189
Y + VT ++ + +Q+ S+ + L+YP MQ D Y G+D
Sbjct: 130 YCMDNFRLCTIVTEHDAKKAGAEVVKQVENSL-LSGLLYPGMQALDEEYLDSDAQFGGVD 188
Query: 190 QRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQFKEIKAQ 249
QRK A KY P++ G K K + + ++ GL A
Sbjct: 189 QRKIFTFAE------KYLPML--GLK-KRIHLMSPMIPGL------------------AG 221
Query: 250 MKMSKS-KPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFREEPTE---- 304
KMS S + + I D E +K+K+ KA C V N +L+ A+H+IF +
Sbjct: 222 GKMSASGNENNKIDILDDAETVKKKINKALCVEAAVENNGLLELAKHVIFPVLALKGIPA 281
Query: 305 FTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYFERHPEP 364
TI+R K+GG V+Y ++E L+ ++ KL P DLK +++ L LL+ IR F + E
Sbjct: 282 LTINREEKWGGPVSYNSYELLELEYVNRKLSPQDLKIGISDSLNFLLESIRLEFAENKEF 341
Query: 365 LELM 368
E++
Sbjct: 342 QEIL 345
>emb|CAB60885.2| (AL132880) predicted using Genefinder; preliminary prediction
[Caenorhabditis elegans]
Length = 540
Score = 92.1 bits (225), Expect = 1e-17
Identities = 93/354 (26%), Positives = 162/354 (45%), Gaps = 42/354 (11%)
Query: 4 EERINLVLKKPTEEVLTVENLRHLFEVGAPLQH-YIGFEISGYIHLGTGLMAGAKIADFQ 62
+E L+L+ +E L V+ L E + H Y G +G H+G L+ KIADF
Sbjct: 17 KETRELILRN-LQESLGVDKLTKQLETPGKVPHVYWGTATTGKPHVGY-LVPMRKIADFL 74
Query: 63 KAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLAS 122
+AG+K I AD H+++ D + E+++ + Y V ++ ++ + +++ F +
Sbjct: 75 QAGLKVTILFADLHAYL-DNMKSSWELLKCRVIYYENV-IKALLQSLDVPIEQLYFKKGT 132
Query: 123 EILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQGVT 182
E + +Y V+ +S V+ +++ + +Q+ ES + L+YP++Q D Y V
Sbjct: 133 EYQLSREYTDDVLRLSAQVSQRDALKAGAEVVKQV-ESPLLSGLLYPLLQALDEQYLKVD 191
Query: 183 IAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQ 242
G+DQRK ++A E KLK H L P V +T
Sbjct: 192 GQFGGVDQRKIFILAEEQLPKLKLGKRWH-----------------LMNPMVPGLTG--- 231
Query: 243 FKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFR-EE 301
KMS S+ S + + D PE+++ K+ A C +R+ N VL + ++F
Sbjct: 232 -------TKMSSSEEDSKIDVLDEPEKVRSKIMGAAC-SRDQPDNGVLSFYNFVLFPIVS 283
Query: 302 PTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIR 355
P I F + LK+ + +GKL LK +A++L+ LL+ +R
Sbjct: 284 PNAIEIENQQFF-------DIDSLKRAYLDGKLDENTLKTFLADFLVNLLEKVR 330
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.320 0.139 0.406
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 141220035
Number of Sequences: 2977
Number of extensions: 6077400
Number of successful extensions: 14987
Number of sequences better than 1.0e-10: 22
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 14892
Number of HSP's gapped (non-prelim): 28
length of query: 375
length of database: 189,106,746
effective HSP length: 55
effective length of query: 320
effective length of database: 156,189,961
effective search space: 49980787520
effective search space used: 49980787520
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 166 (69.1 bits)