BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1728 (tyrS) DE:tyrosyl-tRNA synthetase (tyrS)
         (375 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||B75072 tyrosyl-tRNA synthetase (tyrs) PAB1728 - Pyrococcus ...   764  0.0
pir||F71093 tyrosine--tRNA ligase (EC 6.1.1.1) - Pyrococcus hori...   735  0.0
pir||E72512 probable tyrosyl-tRNA synthetase APE2074 - Aeropyrum...   304  9e-82
gb|AAK40439.1| Tyrosyl-tRNA synthetase (tyrS) [Sulfolobus solfat...   281  8e-75
sp|P95982|SYY_SULSO TYROSYL-TRNA SYNTHETASE (TYROSINE--TRNA LIGA...   281  8e-75
pir||T03741 probable tyrosine--tRNA ligase (EC 6.1.1.1) - common...   224  2e-57
gb|AAC69137.1| (U78721) putative tyrosyl-tRNA synthetase [Arabid...   216  4e-55
gi|11498382 tyrosyl-tRNA synthetase (tyrS) [Archaeoglobus fulgid...   213  2e-54
gb|AAF16759.1|AC010155_12 (AC010155) F3M18.22 [Arabidopsis thali...   206  4e-52
sp|Q57834|SYY_METJA TYROSYL-TRNA SYNTHETASE (TYROSINE--TRNA LIGA...   200  2e-50
emb|CAC11652.1| (AL445064) probable tyrosyl-tRNA synthetase [The...   196  3e-49
sp|O27795|SYY_METTH TYROSYL-TRNA SYNTHETASE (TYROSINE--TRNA LIGA...   191  1e-47
emb|CAB94018.1| (AL358652) tyrosyl-tRNA synthetase isolog [Leish...   190  2e-47
gb|AAG20359.1| (AE005109) tyrosyl-tRNA synthetase; TyrS [Halobac...   155  7e-37
gi|6321624 tyrosyl-tRNA synthetase, cytoplasmic; Tys1p [Saccharo...   149  6e-35
gi|4507947 tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase; tyr...   142  7e-33
sp|P54577|SYY_HUMAN TYROSYL-TRNA SYNTHETASE (TYROSYL--TRNA LIGAS...   142  7e-33
gb|AAC82467.1| (AF087021) tyrosyl-tRNA synthetase; tyrosine--tRN...   141  2e-32
gb|AAF49462.1| (AE003527) CG4561 gene product [Drosophila melano...   136  4e-31
sp|O14055|SYYC_SCHPO TYROSYL-TRNA SYNTHETASE, CYTOPLASMIC (TYROS...   120  2e-26
prf||2122232A Tyr-tRNA synthetase [Pneumocystis carinii]              110  3e-23
emb|CAB60885.2| (AL132880) predicted using Genefinder; prelimina...    92  1e-17

>pir||B75072 tyrosyl-tRNA synthetase (tyrs) PAB1728 - Pyrococcus abyssi  (strain
           Orsay) >gi|5458391|emb|CAB49879.1| (AJ248286)
           tyrosyl-tRNA synthetase (tyrS) [Pyrococcus abyssi]
           Length = 375
           
 Score =  764 bits (1951), Expect = 0.0
 Identities = 375/375 (100%), Positives = 375/375 (100%)

Query: 1   MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60
           MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD
Sbjct: 1   MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60

Query: 61  FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL 120
           FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL
Sbjct: 61  FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL 120

Query: 121 ASEILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQG 180
           ASEILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQG
Sbjct: 121 ASEILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQG 180

Query: 181 VTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSE 240
           VTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSE
Sbjct: 181 VTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSE 240

Query: 241 EQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFRE 300
           EQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFRE
Sbjct: 241 EQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFRE 300

Query: 301 EPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYFER 360
           EPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYFER
Sbjct: 301 EPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYFER 360

Query: 361 HPEPLELMRSVKITR 375
           HPEPLELMRSVKITR
Sbjct: 361 HPEPLELMRSVKITR 375


>pir||F71093 tyrosine--tRNA ligase (EC 6.1.1.1) - Pyrococcus horikoshii
           >gi|3257425|dbj|BAA30108.1| (AP000004) 375aa long
           hypothetical tyrosyl-tRNA synthetase [Pyrococcus
           horikoshii]
           Length = 375
           
 Score =  735 bits (1876), Expect = 0.0
 Identities = 356/375 (94%), Positives = 367/375 (96%)

Query: 1   MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60
           MDIEERINLVLKKPTEEVLTVENLRHLFE+GAPLQHYIGFEISGYIHLGTGLMAGAKIAD
Sbjct: 1   MDIEERINLVLKKPTEEVLTVENLRHLFEIGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60

Query: 61  FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL 120
           FQKAGIKTR+FLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL
Sbjct: 61  FQKAGIKTRVFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL 120

Query: 121 ASEILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQG 180
           ASEILE GDYWQTVIDISKNVTLSRVMRSITIMGRQMGE+IDFAKLIYPMMQVADIFYQG
Sbjct: 121 ASEILEKGDYWQTVIDISKNVTLSRVMRSITIMGRQMGEAIDFAKLIYPMMQVADIFYQG 180

Query: 181 VTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSE 240
           VTIAHAGMDQRKAHVIAIEVAQKL+YHPIVH GEKLKPVAVHHHLLLGLQEPP WPI SE
Sbjct: 181 VTIAHAGMDQRKAHVIAIEVAQKLRYHPIVHEGEKLKPVAVHHHLLLGLQEPPKWPIESE 240

Query: 241 EQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFRE 300
           E+FKEIKAQMKMSKSKPYSAVFIHDSPEEI+QKLRKAFCPAREV YNPVLDW E+IIFRE
Sbjct: 241 EEFKEIKAQMKMSKSKPYSAVFIHDSPEEIRQKLRKAFCPAREVRYNPVLDWVEYIIFRE 300

Query: 301 EPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYFER 360
           EPTEFT+HRPAKFGGDVTYTTFEELK+DFAEGKLHPLDLKNAVAEYLI LL+PIR YFE+
Sbjct: 301 EPTEFTVHRPAKFGGDVTYTTFEELKRDFAEGKLHPLDLKNAVAEYLINLLEPIRRYFEK 360

Query: 361 HPEPLELMRSVKITR 375
           HPEPLELMRSVKITR
Sbjct: 361 HPEPLELMRSVKITR 375


>pir||E72512 probable tyrosyl-tRNA synthetase APE2074 - Aeropyrum pernix
           (strain K1) >gi|5105773|dbj|BAA81085.1| (AP000063) 364aa
           long hypothetical tyrosyl-tRNA synthetase [Aeropyrum
           pernix]
           Length = 364
           
 Score =  304 bits (771), Expect = 9e-82
 Identities = 167/378 (44%), Positives = 251/378 (66%), Gaps = 20/378 (5%)

Query: 1   MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60
           +D+EER N + +  T E++T E L+ L   GA ++ YIG+E SG  H+G  L+   K+ D
Sbjct: 4   VDVEERFNRIARN-TVEIVTEEELKGLLASGARIKGYIGYEPSGVAHIGW-LVWMYKVKD 61

Query: 61  FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL 120
             +AG+   +  A WH++INDKLGGD+++I+  A    +V     +E  G   ++V FV 
Sbjct: 62  LVEAGVDFSVLEATWHAYINDKLGGDMDLIRAAARIVRRV-----MEAAGVPVERVRFVD 116

Query: 121 ASEILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGES-IDFAKLIYPMMQVADIFYQ 179
           A E+  + DYW  VI ++K  +L+RV R++TIMGR+  E+ +D +KLIYP+MQV+DIFY 
Sbjct: 117 AEELASDKDYWGLVIRVAKRASLARVRRALTIMGRRAEEAEVDASKLIYPLMQVSDIFYM 176

Query: 180 GVTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITS 239
            + IA  GMDQRKAH++A +VA+KL        G K KPVA+H  ++  LQ P      S
Sbjct: 177 DLDIALGGMDQRKAHMLARDVAEKL--------GRK-KPVAIHTPIISSLQGPGRME-AS 226

Query: 240 EEQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFR 299
           + +  ++ A++KMSKSKP +AVF+ DS ++I++K+RKA+CPA++V  NPVL+ A +I+F 
Sbjct: 227 QGEIDDVLAEVKMSKSKPETAVFVVDSDDDIRRKIRKAYCPAKQVQGNPVLEIARYILFA 286

Query: 300 EEPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYFE 359
            +     + RPAK+GG V YT++EEL++D+ +G+LHPLDLKNAVAE LIE+++PIR    
Sbjct: 287 RDGFTLRVDRPAKYGGPVEYTSYEELERDYTDGRLHPLDLKNAVAESLIEVVRPIRGAVL 346

Query: 360 RHPEPLELMRSV--KITR 375
             P     + ++  K+TR
Sbjct: 347 GDPAMKRALEAIEGKVTR 364


>gb|AAK40439.1| Tyrosyl-tRNA synthetase (tyrS) [Sulfolobus solfataricus]
           Length = 366
           
 Score =  281 bits (712), Expect = 8e-75
 Identities = 157/375 (41%), Positives = 237/375 (62%), Gaps = 24/375 (6%)

Query: 1   MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60
           M I++R+ L+++  T EV+T++ LR   E    L+ YIGFE SG  H+G  L+   K+ D
Sbjct: 6   MSIDQRLQLIMRN-TAEVITIDELRKKLESDEKLKGYIGFEPSGLFHIGW-LIWTQKVKD 63

Query: 61  FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVM---GGDPKKVE 117
             +AGI   +  A WH+WINDKLGGD+ +I        K+  + ++EV+   G D  K+ 
Sbjct: 64  LVEAGINMTLLRAAWHAWINDKLGGDMNLI--------KMAADYAVEVIKNYGVDVGKLN 115

Query: 118 FVLASEILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGES-IDFAKLIYPMMQVADI 176
            V A +I++  DYW  VI ++KN +L+R+ R++TIMGR+  E+ ID +KLIYP MQV+DI
Sbjct: 116 IVDADDIVKEKDYWALVIKVAKNASLARIKRALTIMGRRAEEAEIDASKLIYPAMQVSDI 175

Query: 177 FYQGVTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWP 236
           FY  + IA  G DQRKAH++A +VA+K+          K K V++H  LL+GLQ      
Sbjct: 176 FYLDLDIALGGTDQRKAHMLARDVAEKMG---------KKKIVSIHTPLLVGLQGGQRMN 226

Query: 237 ITSEEQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHI 296
           IT   +  +I+A++KMSKSKP SA+F++DS E++++K+  A+CP      NP+L   ++I
Sbjct: 227 ITEGMEEDDIQAEIKMSKSKPESAIFVNDSREDVERKIMGAYCPKGVAENNPILQILKYI 286

Query: 297 IFREEPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIRE 356
           IF        I R  K+GGDV +  +EEL++ + EGK+HP+DLK   A  L E+L+PIR+
Sbjct: 287 IF-PRYNFVKIERDIKYGGDVEFKDYEELERTYIEGKIHPMDLKKTTARKLNEILEPIRK 345

Query: 357 YFERHPEPLELMRSV 371
             E+ PE  E+++ +
Sbjct: 346 SLEKKPEFEEMIQKI 360


>sp|P95982|SYY_SULSO TYROSYL-TRNA SYNTHETASE (TYROSINE--TRNA LIGASE) (TYRRS)
           >gi|7450987|pir||S75410 tyrosine--tRNA ligase (EC
           6.1.1.1) - Sulfolobus solfataricus
           >gi|1707816|emb|CAA69524.1| (Y08257) tyrosyl tRNA
           synthetase [Sulfolobus solfataricus]
           Length = 366
           
 Score =  281 bits (712), Expect = 8e-75
 Identities = 157/375 (41%), Positives = 237/375 (62%), Gaps = 24/375 (6%)

Query: 1   MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60
           M I++R+ L+++  T EV+T++ LR   E    L+ YIGFE SG  H+G  L+   K+ D
Sbjct: 6   MSIDQRLQLIMRN-TAEVITIDELRKKLESDEKLKGYIGFEPSGLFHIGW-LIWTQKVKD 63

Query: 61  FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVM---GGDPKKVE 117
             +AGI   +  A WH+WINDKLGGD+ +I        K+  + ++EV+   G D  K+ 
Sbjct: 64  LVEAGINMTLLRAAWHAWINDKLGGDMNLI--------KMAADYAVEVIKNYGVDVGKLN 115

Query: 118 FVLASEILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGES-IDFAKLIYPMMQVADI 176
            V A +I++  DYW  VI ++KN +L+R+ R++TIMGR+  E+ ID +KLIYP MQV+DI
Sbjct: 116 IVDADDIVKEKDYWALVIKVAKNASLARIKRALTIMGRRAEEAEIDASKLIYPAMQVSDI 175

Query: 177 FYQGVTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWP 236
           FY  + IA  G DQRKAH++A +VA+K+          K K V++H  LL+GLQ      
Sbjct: 176 FYLDLDIALGGTDQRKAHMLARDVAEKMG---------KKKIVSIHTPLLVGLQGGQRMN 226

Query: 237 ITSEEQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHI 296
           IT   +  +I+A++KMSKSKP SA+F++DS E++++K+  A+CP      NP+L   ++I
Sbjct: 227 ITEGMEEDDIQAEIKMSKSKPESAIFVNDSREDVERKIMGAYCPKGVAENNPILQILKYI 286

Query: 297 IFREEPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIRE 356
           IF        I R  K+GGDV +  +EEL++ + EGK+HP+DLK   A  L E+L+PIR+
Sbjct: 287 IF-PRYNFVKIERDIKYGGDVEFKDYEELERTYIEGKIHPMDLKKTTARKLNEILEPIRK 345

Query: 357 YFERHPEPLELMRSV 371
             E+ PE  E+++ +
Sbjct: 346 SLEKKPEFEEMIQKI 360


>pir||T03741 probable tyrosine--tRNA ligase (EC 6.1.1.1) - common tobacco
           >gi|1841468|emb|CAA71881.1| (Y10990) Tyrosyl-tRNA
           synthetase [Nicotiana tabacum]
           Length = 408
           
 Score =  224 bits (564), Expect = 2e-57
 Identities = 127/374 (33%), Positives = 206/374 (54%), Gaps = 31/374 (8%)

Query: 1   MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60
           M +EE+  +V +   EE +  + L +L         Y GFE SG +H+  G++    +  
Sbjct: 58  MSLEEKFKIV-RSIGEECIQEDELMNLLAKKPQPVCYDGFEPSGRMHIAQGVLKALNVNK 116

Query: 61  FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL 120
              AG K +I++ADW + +N+K+GGDL+ I+ V     ++     + + GG    VEF+ 
Sbjct: 117 LTSAGCKVKIWIADWFAQLNNKMGGDLKKIEVVGQYLIEIWKAVGMNLEGGH---VEFLW 173

Query: 121 ASEILENG--DYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFY 178
           +S+ + +   +YW  V+D+++   L R++R   IMGR   + +  A++ YP MQ ADIF+
Sbjct: 174 SSKEINSRAHEYWPLVMDVARRNKLPRILRCCQIMGRSEQDELTAAQIFYPCMQCADIFF 233

Query: 179 QGVTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPIT 238
               I   GMDQRK +V+A E    ++         K KP+ + HH+L GLQE       
Sbjct: 234 LKADICQLGMDQRKVNVLAREYCDDIR--------RKNKPIILSHHMLPGLQE------- 278

Query: 239 SEEQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIF 298
                     Q KMSKS P S++++ D   ++  K++KAFCP + V  NP L++ ++I+ 
Sbjct: 279 ---------GQEKMSKSDPSSSIYMEDEEADVNLKIKKAFCPPKVVEKNPCLEYIKYIVL 329

Query: 299 REEPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYF 358
                EF I R A+ G D TY  FEEL  D+  G LHP DLK A+++ + ++L+P+R++F
Sbjct: 330 -PWFNEFKIERSAENGADKTYKNFEELAADYESGNLHPADLKPALSKAINKILQPVRDHF 388

Query: 359 ERHPEPLELMRSVK 372
           +   +  +LM+ VK
Sbjct: 389 KNDQKAKDLMKRVK 402


>gb|AAC69137.1| (U78721) putative tyrosyl-tRNA synthetase [Arabidopsis thaliana]
           Length = 460
           
 Score =  216 bits (544), Expect = 4e-55
 Identities = 127/355 (35%), Positives = 200/355 (55%), Gaps = 33/355 (9%)

Query: 2   DIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIADF 61
           ++E+R  +V +   EE +  E L++L    A    Y GFE SG +H+  G+M    +   
Sbjct: 4   EVEKRYKIV-RSIGEECIQEEELKNLLAKKAAPICYDGFEPSGRMHIAQGVMKVINVNKM 62

Query: 62  QKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLA 121
             AG + +I++ADW + +N+K+GGDL+ I+ V  +YF    ++  +  G D  KVEF+ +
Sbjct: 63  TSAGCRVKIWIADWFAQLNNKMGGDLKKIRVVG-EYF----QEIWKAAGMDNDKVEFLWS 117

Query: 122 SEILEN--GDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQ 179
           SE + +    YW  V+DI++   L R++R + IMGR   + +  A+++YP MQ ADIF+ 
Sbjct: 118 SEEINSKADKYWPLVMDIARKNKLPRILRCVQIMGRSETDELSAAQILYPCMQCADIFFL 177

Query: 180 GVTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITS 239
              I   GMDQRK +V+A E    +K         K KP+ + HH+L GLQ+        
Sbjct: 178 EADICQLGMDQRKVNVLAREYCDDIK--------RKNKPIILSHHMLPGLQQ-------- 221

Query: 240 EEQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFR 299
                    Q KMSKS P SA+F+ D   E+  K++KA+CP + V  NP L++ ++II  
Sbjct: 222 --------GQEKMSKSDPLSAIFMEDEEAEVNVKIKKAYCPPKVVKGNPCLEYIKYIIL- 272

Query: 300 EEPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPI 354
               EFT+ R  ++GG+ TY +FE++  D+  G+LHP DLK  +   L ++L+ I
Sbjct: 273 PWFDEFTVERNEEYGGNKTYKSFEDIAADYESGELHPGDLKKGLMNALNKILQVI 327


>gi|11498382 tyrosyl-tRNA synthetase (tyrS) [Archaeoglobus fulgidus]
           >gi|3122912|sp|O29482|SYY_ARCFU TYROSYL-TRNA SYNTHETASE
           (TYROSINE--TRNA LIGASE) (TYRRS) >gi|7450986|pir||H69346
           tyrosyl-tRNA synthetase (tyrS) homolog - Archaeoglobus
           fulgidus >gi|2649832|gb|AAB90462.1| (AE001051)
           tyrosyl-tRNA synthetase (tyrS) [Archaeoglobus fulgidus]
           Length = 323
           
 Score =  213 bits (538), Expect = 2e-54
 Identities = 142/357 (39%), Positives = 205/357 (56%), Gaps = 41/357 (11%)

Query: 1   MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60
           MDI E++ L+ +   EEV+T E LR L E     + Y+G+E SG IHLG  +M   K+ D
Sbjct: 1   MDITEKLRLITRN-AEEVVTEEELRQLIETKEKPRAYVGYEPSGEIHLGH-MMTVQKLMD 58

Query: 61  FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL 120
            Q+AG +  + LAD H+++N+K  G  E I EVA  Y K    K    +G D  + +FVL
Sbjct: 59  LQEAGFEIIVLLADIHAYLNEK--GTFEEIAEVA-DYNK----KVFIALGLDESRAKFVL 111

Query: 121 ASEILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQG 180
            SE   + DY   V+ +++  TL+R  RS+  + R+  + +  +++IYP+MQ  DI + G
Sbjct: 112 GSEYQLSRDYVLDVLKMARITTLNRARRSMDEVSRRKEDPM-VSQMIYPLMQALDIAHLG 170

Query: 181 VTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSE 240
           V +A  G+DQRK H++A E   +L Y           PV +H  +L+GL           
Sbjct: 171 VDLAVGGIDQRKIHMLARENLPRLGYS---------SPVCLHTPILVGLDG--------- 212

Query: 241 EQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAE-HIIFR 299
                     KMS SK  + + + D PEE+++K+RKA+CPA  V  NP+LD A+ HI+ R
Sbjct: 213 ---------QKMSSSKG-NYISVRDPPEEVERKIRKAYCPAGVVEENPILDIAKYHILPR 262

Query: 300 EEPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIRE 356
               +  + R AKFGGDV Y +FEEL +DF  G+LHPLDLK AVA+YL  LL+  R+
Sbjct: 263 FG--KIVVERDAKFGGDVEYASFEELAEDFKSGQLHPLDLKIAVAKYLNMLLEDARK 317


>gb|AAF16759.1|AC010155_12 (AC010155) F3M18.22 [Arabidopsis thaliana]
           Length = 895
           
 Score =  206 bits (518), Expect = 4e-52
 Identities = 130/404 (32%), Positives = 215/404 (53%), Gaps = 61/404 (15%)

Query: 2   DIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGT----------- 50
           ++E+R N+V +   E+ +  + L+ L    A    Y GFE SG +H+             
Sbjct: 24  EVEKRYNVV-RSVGEQCIHDDELKDLLAKKAAPVCYDGFEPSGRMHIAQLALEFFYVLSS 82

Query: 51  -----------------GLMAGAKIADFQKAGIKTRIFLADWHSWINDKLGGDLEVIQEV 93
                            GLM    +     AG + +I++ADW +++N+KLGGDL+ I+ V
Sbjct: 83  LSEKLLLARLTLLLPWQGLMKIMNVNKLTSAGCRVKIWIADWFAYMNNKLGGDLKKIRVV 142

Query: 94  ALKYFKVGMEKSIEVMGGDPKKVEFVLAS-EILENGD-YWQTVIDISKNVTLSRVMRSIT 151
             +YFK    +  +  G + + VEF+ +S EI   GD YW  V+DI+   +L+++ R + 
Sbjct: 143 G-EYFK----EIFQAAGMNSENVEFLWSSDEINAKGDEYWPLVMDIACRNSLAQIKRCMP 197

Query: 152 IMGRQMGESIDFAKLIYPMMQVADIFYQGVTIAHAGMDQRKAHVIAIEVAQKLKYHPIVH 211
           IMG    E +  A ++Y  MQ AD F+    I   GMDQ+  +++A +    +K      
Sbjct: 198 IMGLSENEELSAAHILYVCMQCADTFFLEADICQLGMDQQTVNLLARDYCDVVK------ 251

Query: 212 NGEKLKPVAVHHHLLLGLQEPPVWPITSEEQFKEIKAQMKMSKSKPYSAVFIHDSPEEIK 271
              + KPV + HH+L GLQ+                 Q KMSKS P SA+F+ D   E+ 
Sbjct: 252 --RENKPVILSHHMLPGLQQ----------------GQKKMSKSDPSSAIFMEDEEAEVN 293

Query: 272 QKLRKAFCPAREVNYNPVLDWAEHIIFREEPTEFTIHRPAKFGGDVTYTTFEELKKDFAE 331
            K++KA+CP   V  NP L++ +HII     +EFT+ R  K+GG+ T+ +FE++  D+  
Sbjct: 294 VKIKKAYCPPDIVEGNPCLEYVKHIILPWF-SEFTVERDEKYGGNRTFKSFEDITTDYES 352

Query: 332 GKLHPLDLKNAVAEYLIELLKPIREYFERHPEPLELMRSVKITR 375
           G+LHP DLK+A+++ L ++L+P+R++F+ +     L++ VK+ +
Sbjct: 353 GQLHPKDLKDALSKALNKILQPVRDHFKTNSRAKNLLKQVKVIK 396


 Score =  196 bits (493), Expect = 4e-49
 Identities = 119/340 (35%), Positives = 186/340 (54%), Gaps = 33/340 (9%)

Query: 10  VLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIADFQKAGIKTR 69
           +++   EE +  + L++L         Y GFE SG +H+  G+M    +     AG + +
Sbjct: 485 IVRSIGEECIQEDELKNLLAKKPAPICYDGFEPSGRMHIAQGVMKVTNVNKLTSAGCQVK 544

Query: 70  IFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLASEIL--EN 127
           I++ADW + +N+KLGGDLE I+ V  +YFK    +  +  G +  KVEF+ AS+ +  + 
Sbjct: 545 IWIADWFAQLNNKLGGDLERIRVVG-EYFK----EIWQAGGMNNDKVEFLWASDEINGKG 599

Query: 128 GDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQGVTIAHAG 187
             YW  V+DI++   L R++R   IMGR   E +  A+++YP MQ ADIF     I   G
Sbjct: 600 SKYWPLVMDIARRNNLRRILRCGQIMGRSETEVLSAAQILYPCMQCADIFLLEADICQLG 659

Query: 188 MDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQFKEIK 247
           MDQRK +++A E    +K         K KP+ + HH+L GLQ+                
Sbjct: 660 MDQRKVNMLAREYCADIK--------RKNKPIILSHHMLPGLQQ---------------- 695

Query: 248 AQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFREEPTEFTI 307
            Q KMSKS P SA+F+ D   ++ +K+ KA+CP + V  NP L++ ++I+      EF +
Sbjct: 696 GQEKMSKSDPSSAIFMEDEEADVNEKISKAYCPPKTVEGNPCLEYVKYIVL-PRFNEFKV 754

Query: 308 HRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYL 347
               K GG+ T+ +FE++  D+  G+LHP DLK A+ + L
Sbjct: 755 -ESEKNGGNKTFNSFEDIVADYETGELHPEDLKKALMKAL 793


>sp|Q57834|SYY_METJA TYROSYL-TRNA SYNTHETASE (TYROSINE--TRNA LIGASE) (TYRRS)
           >gi|2129341|pir||E64348 tyrosine--tRNA ligase (EC
           6.1.1.1) - Methanococcus jannaschii
           >gi|1591094|gb|AAB98375.1| (U67491) tyrosyl-tRNA
           synthetase (trS) [Methanococcus jannaschii]
           Length = 306
           
 Score =  200 bits (503), Expect = 2e-50
 Identities = 136/347 (39%), Positives = 197/347 (56%), Gaps = 48/347 (13%)

Query: 10  VLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIADFQKAGIKTR 69
           ++K+ T E+++ E LR + +       YIGFE SG IHLG  L    K+ D Q AG    
Sbjct: 6   MIKRNTSEIISEEELREVLKKDEK-SAYIGFEPSGKIHLGHYLQI-KKMIDLQNAGFDII 63

Query: 70  IFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLASEILENGD 129
           I LAD H+++N K  G+L+ I+++   Y K    K  E MG    K ++V  SE   + D
Sbjct: 64  ILLADLHAYLNQK--GELDEIRKIG-DYNK----KVFEAMG---LKAKYVYGSEFQLDKD 113

Query: 130 YWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQGVTIAHAGMD 189
           Y   V  ++   TL R  RS+ ++ R+  E+   A++IYP+MQV DI Y GV +A  GM+
Sbjct: 114 YTLNVYRLALKTTLKRARRSMELIARE-DENPKVAEVIYPIMQVNDIHYLGVDVAVGGME 172

Query: 190 QRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQFKEIKAQ 249
           QRK H++A E+  K             K V +H+ +L GL                   +
Sbjct: 173 QRKIHMLARELLPK-------------KVVCIHNPVLTGLD-----------------GE 202

Query: 250 MKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFREEPTEFTIHR 309
            KMS SK  + + + DSPEEI+ K++KA+CPA  V  NP+++ A++  F E P   TI R
Sbjct: 203 GKMSSSKG-NFIAVDDSPEEIRAKIKKAYCPAGVVEGNPIMEIAKY--FLEYP--LTIKR 257

Query: 310 PAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIRE 356
           P KFGGD+T  ++EEL+  F   +LHP+DLKNAVAE LI++L+PIR+
Sbjct: 258 PEKFGGDLTVNSYEELESLFKNKELHPMDLKNAVAEELIKILEPIRK 304


>emb|CAC11652.1| (AL445064) probable tyrosyl-tRNA synthetase [Thermoplasma
           acidophilum]
           Length = 332
           
 Score =  196 bits (494), Expect = 3e-49
 Identities = 126/352 (35%), Positives = 196/352 (54%), Gaps = 41/352 (11%)

Query: 13  KPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIADFQKAGIKTRIFL 72
           K T EV+T E+   L E  + ++ YIG E SG  H+ T +M   K+A+ Q   IK  + L
Sbjct: 9   KNTREVVTREDAERL-EGKSDIKSYIGIEPSGIPHIATAVMWPRKLAEIQD-DIKVTVLL 66

Query: 73  ADWHSWINDKLGGDLEVIQ---EVALKYFKV-GMEKSIEVMGGDPKKVEFVLASEILENG 128
           ADWH+ IN+KL GDL++I+   E+  K F+  G+ K+           ++V AS+++++ 
Sbjct: 67  ADWHAMINNKLHGDLDLIRKGGEILRKTFQAEGLTKA-----------DYVWASDLVDSS 115

Query: 129 DYWQTVIDISKNVTLSRVMRSITIMGRQMGESI-DFAKLIYPMMQVADIFYQGVTIAHAG 187
           +YW+  ID +K  TL RV+RS+ IMGR   ++  DF+  +YP+MQV DIFY  V +A  G
Sbjct: 116 EYWRMFIDTAKRSTLKRVIRSLPIMGRNETDAEKDFSMYLYPIMQVTDIFYLDVDMAFGG 175

Query: 188 MDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQFKEIK 247
           MDQR AH++A ++A+K+K         + K V+VH  LL  L+               + 
Sbjct: 176 MDQRHAHMLARDIAEKMK---------RKKVVSVHGFLLSSLKGN-----------ARMD 215

Query: 248 AQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFREEPTEFTI 307
             +KMSKS P SA+ + D  E+I++K+  A+CP ++V  NPV +  ++II         I
Sbjct: 216 NFVKMSKSDPNSAILVTDHMEDIERKINAAYCPPQQVEGNPVAEIMKYIIIPYYGKSIEI 275

Query: 308 HRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYFE 359
           H      G +   + E   + +  G++ P DLK+ VA  L E+++P R   E
Sbjct: 276 HGS---NGVINLDSVENFDQAYQRGEIQPADLKHKVATILNEMVEPARRSLE 324


>sp|O27795|SYY_METTH TYROSYL-TRNA SYNTHETASE (TYROSINE--TRNA LIGASE) (TYRRS)
           >gi|7450985|pir||H69102 tyrosine--tRNA ligase (EC
           6.1.1.1) - Methanobacterium thermoautotrophicum (strain
           Delta H) >gi|2622897|gb|AAB86233.1| (AE000932)
           tyrosyl-tRNA synthetase [Methanobacterium
           thermoautotrophicum]
           Length = 319
           
 Score =  191 bits (480), Expect = 1e-47
 Identities = 123/343 (35%), Positives = 190/343 (54%), Gaps = 39/343 (11%)

Query: 17  EVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIADFQKAGIKTRIFLADWH 76
           EV+T E L  + +   P+  Y G+E SG IHLG  L    K+ + Q AG + +I LAD+H
Sbjct: 14  EVITPEELMDVLKKDEPVV-YTGYEPSGRIHLGHALTV-RKLRELQDAGFRVKILLADYH 71

Query: 77  SWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLASEILENGDYWQTVID 136
           +++N K  G +E I+E+A  Y     +K    +G  P++ EF+L S      +Y   V  
Sbjct: 72  AYLNGK--GSMERIRELA-DY----NQKCFLALGLSPERTEFILGSSFQTEPEYTDLVYR 124

Query: 137 ISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQGVTIAHAGMDQRKAHVI 196
           ++   TL R  RS+  + R+  +    A++IYP+MQV D+ Y GV +A  GM+QRK H++
Sbjct: 125 LALITTLLRAKRSMAQITRESRDH-KVAEVIYPLMQVIDMVYLGVDVALGGMEQRKIHML 183

Query: 197 AIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQFKEIKAQMKMSKSK 256
           A E   +L +           PV +H  LL G                      KMS SK
Sbjct: 184 ARENLPRLGFDA---------PVCIHTPLLHGTD-----------------GSEKMSSSK 217

Query: 257 PYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFREEPTEFTIHRPAKFGGD 316
             + + + DSP+EI++K++K++CP  E   NP+++  ++ I  E     TI RP KFGGD
Sbjct: 218 G-NFIAVDDSPDEIREKVKKSYCPMGETEGNPIIEIVKYFIMPEYGM-MTIRRPEKFGGD 275

Query: 317 VTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYFE 359
           +     +EL + ++  +LHPLDLKNAV++YL+++L+P+REY E
Sbjct: 276 LELE-LDELLEMYSSSELHPLDLKNAVSDYLVDMLEPVREYME 317


>emb|CAB94018.1| (AL358652) tyrosyl-tRNA synthetase isolog [Leishmania major]
           Length = 682
           
 Score =  190 bits (479), Expect = 2e-47
 Identities = 125/392 (31%), Positives = 205/392 (51%), Gaps = 55/392 (14%)

Query: 1   MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60
           M+ +ER  L L+   EE +    LR+L E    ++ Y GFE SG +H+  G+     +  
Sbjct: 1   MNTDERYKL-LRSVGEECIQESELRNLIEKKPLIRCYDGFEPSGRMHIAQGIFKAVNVNK 59

Query: 61  FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL 120
              AG +   ++ADW + +NDK+GG+LE I+ V     +V      +  G D  KV F+ 
Sbjct: 60  CTAAGCEFVFWVADWFALMNDKVGGELEKIRIVGRYLIEVW-----KAAGMDMDKVLFLW 114

Query: 121 AS-EILENGD-YWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFY 178
           +S EI  + D YW+ V+DI +  T++R+ +  TIMG+  G ++  A+++YP+MQ  DIF+
Sbjct: 115 SSEEITSHADTYWRMVLDIGRQNTIARIKKCCTIMGKTEG-TLTAAQVLYPLMQCCDIFF 173

Query: 179 QGVTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPIT 238
               I   G+DQRK +++A E    +        G KLKPV + HH+L GL++       
Sbjct: 174 LKADICQLGLDQRKVNMLAREYCDLI--------GRKLKPVILSHHMLAGLKQ------- 218

Query: 239 SEEQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFC---------------PARE 283
                     Q KMSKS P SA+F+ D+ E++ +K+R+A+C               P   
Sbjct: 219 ---------GQAKMSKSDPDSAIFMEDTEEDVARKIRQAYCPRVKQSASAITDDGAPVAT 269

Query: 284 VNYNPVLDWAEHIIFREEPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAV 343
            + NPVLD+ + +++       TI          TY T+E+L++ F   ++    LK+ +
Sbjct: 270 DDRNPVLDYFQCVVYARPGAAATI-------DGTTYATYEDLEQAFVSDEVSEDALKSCL 322

Query: 344 AEYLIELLKPIREYFERHPEPLELMRSVKITR 375
            + +  LL+P+R++F  + E  EL+ +VK  R
Sbjct: 323 IDEVNALLEPVRQHFASNEEAHELLEAVKSYR 354


>gb|AAG20359.1| (AE005109) tyrosyl-tRNA synthetase; TyrS [Halobacterium sp. NRC-1]
           Length = 327
           
 Score =  155 bits (388), Expect = 7e-37
 Identities = 116/360 (32%), Positives = 181/360 (50%), Gaps = 45/360 (12%)

Query: 1   MDIEERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIAD 60
           M+  ERI     + T EV+T E +R L E     + Y+G+E SG +HLG  L+   K+ D
Sbjct: 1   MNAYERIT----RNTAEVVTEEEVRELAEDPEGKRVYVGYEPSGVLHLGH-LLTANKLMD 55

Query: 61  FQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVL 120
            Q AG++  + LAD H+++NDK  G  E I+  A +     M+      G D  + EFVL
Sbjct: 56  LQDAGMEVVVLLADVHAYLNDK--GSFEEIRATADQ-----MKAQFLAYGLDEDQTEFVL 108

Query: 121 ASEILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQG 180
            S    + DY   +  +    +L R  R++  +  Q GE+   + ++YP+MQ  DI Y  
Sbjct: 109 GSSFQLDEDYELDLHAMQVETSLKRAQRAMAEI--QSGETPKVSHVVYPLMQALDIEYLD 166

Query: 181 VTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSE 240
           + +A  GMDQRK H++A E    + Y          +PV         L  P +  + S 
Sbjct: 167 LDLAIGGMDQRKVHMLAREELPSVGYEK--------RPV---------LHTPIIGDLGSG 209

Query: 241 EQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPARE----VNYNPVLDWAEHI 296
           +         KMS S+  + + + DS  +I++K+  AFCP          NPVL+  ++ 
Sbjct: 210 DG--------KMSSSEGVT-ISMEDSTADIEEKVTGAFCPQTRDPEGETVNPVLELFQYH 260

Query: 297 IFREEPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIRE 356
           +F     E  + RP ++GGD+ Y ++E+L  D   G+LHP D K A+A  L EL++P R+
Sbjct: 261 VFPRFD-EVVVQRPDEYGGDLVYESYEDLADDLESGELHPADAKGALAAALDELIEPGRQ 319


>gi|6321624 tyrosyl-tRNA synthetase, cytoplasmic; Tys1p [Saccharomyces
           cerevisiae] >gi|549037|sp|P36421|SYYC_YEAST TYROSYL-TRNA
           SYNTHETASE, CYTOPLASMIC (TYROSYL--TRNA LIGASE) (TYRRS)
           >gi|539380|pir||A45999 tyrosine--tRNA ligase (EC
           6.1.1.1) [validated] - yeast  (Saccharomyces cerevisiae)
           >gi|173120|gb|AAB59329.1| (L12221) tyrosyl-tRNA
           synthetase [Saccharomyces cerevisiae]
           >gi|1323328|emb|CAA97211.1| (Z72970) ORF YGR185c
           [Saccharomyces cerevisiae] >gi|1430951|emb|CAA67529.1|
           (X99074) G7522 [Saccharomyces cerevisiae]
           Length = 394
           
 Score =  149 bits (372), Expect = 6e-35
 Identities = 115/371 (30%), Positives = 181/371 (47%), Gaps = 39/371 (10%)

Query: 1   MDIEERINLVLKKPTEEVLTVENLRHLFEVGAP-LQHYIGFEISGYIHLGTGLMAGAKIA 59
           +D  E   L+ K   +EVL  + ++ + EV    L+ Y G   +G  H G   +   K+A
Sbjct: 7   VDPNEAFGLITKN-LQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGY-FVPMTKLA 64

Query: 60  DFQKAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFV 119
           DF KAG +  + LAD H+++ D +   LEV+   A KY+++ ++  +  +    +K++FV
Sbjct: 65  DFLKAGCEVTVLLADLHAFL-DNMKAPLEVVNYRA-KYYELTIKAILRSINVPIEKLKFV 122

Query: 120 LASEILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQ 179
           + S      DY   +  +S  V+ +   R+   + +Q+   +  + LIYP+MQ  D  + 
Sbjct: 123 VGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPL-LSGLIYPLMQALDEQFL 181

Query: 180 GVTIAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITS 239
            V     G+DQRK  V+A E    L Y    H    + P         GL +        
Sbjct: 182 DVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVP---------GLAQGG------ 226

Query: 240 EEQFKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHII-- 297
                      KMS S P S + + + P+++K+K+  AFC    V  N +L + +++I  
Sbjct: 227 -----------KMSASDPNSKIDLLEEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAP 275

Query: 298 -----FREEPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLK 352
                F     EF I RP KFGG +TY +FEE+K  F E KL P DLK  VA+ + ELL+
Sbjct: 276 IQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLE 335

Query: 353 PIREYFERHPE 363
           PIR+ F  + E
Sbjct: 336 PIRQEFANNKE 346


>gi|4507947 tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase; tyrosyl tRNA
           ligase [Homo sapiens] >gi|2665519|gb|AAB88409.1|
           (U89436) tyrosyl-tRNA synthetase [Homo sapiens]
           Length = 528
           
 Score =  142 bits (354), Expect = 7e-33
 Identities = 110/355 (30%), Positives = 181/355 (50%), Gaps = 34/355 (9%)

Query: 4   EERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIADFQK 63
           EE+++L+ +   +EVL  E L+ + +    L+ Y G   +G  H+    +  +KIADF K
Sbjct: 8   EEKLHLITRN-LQEVLGEEKLKEILKE-RELKIYWGTATTGKPHVAY-FVPMSKIADFLK 64

Query: 64  AGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLASE 123
           AG +  I  AD H+++ D +    E++ E+ + Y++  ++  +E +G   +K++F+  ++
Sbjct: 65  AGCEVTILFADLHAYL-DNMKAPWELL-ELRVSYYENVIKAMLESIGVPLEKLKFIKGTD 122

Query: 124 ILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQGVTI 183
              + +Y   V  +S  VT     ++   + +Q+   +  + L+YP +Q  D  Y  V  
Sbjct: 123 YQLSKEYTLDVYRLSSVVTQHDSKKAGAEVVKQVEHPL-LSGLLYPGLQALDEEYLKVDA 181

Query: 184 AHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQF 243
              G+DQRK    A +    L Y   VH                 L  P V  +T     
Sbjct: 182 QFGGIDQRKIFTFAEKYLPALGYSKRVH-----------------LMNPMVPGLTGS--- 221

Query: 244 KEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFREEPT 303
                  KMS S+  S + + D  E++K+KL+KAFC    V  N VL + +H++F  + +
Sbjct: 222 -------KMSSSEEESKIDLLDRKEDVKKKLKKAFCEPGNVENNGVLSFIKHVLFPLK-S 273

Query: 304 EFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYF 358
           EF I R  K+GG+ TYT + +L+KDFA   +HP DLKN+V   L +LL PIRE F
Sbjct: 274 EFVILRDEKWGGNKTYTAYVDLEKDFAAEVVHPGDLKNSVEVALNKLLDPIREKF 328


>sp|P54577|SYY_HUMAN TYROSYL-TRNA SYNTHETASE (TYROSYL--TRNA LIGASE) (TYRRS)
           >gi|1184699|gb|AAB39406.1| (U40714) tyrosyl-tRNA
           synthetase [Homo sapiens]
           Length = 388
           
 Score =  142 bits (354), Expect = 7e-33
 Identities = 110/355 (30%), Positives = 181/355 (50%), Gaps = 34/355 (9%)

Query: 4   EERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIADFQK 63
           EE+++L+ +   +EVL  E L+ + +    L+ Y G   +G  H+    +  +KIADF K
Sbjct: 8   EEKLHLITRN-LQEVLGEEKLKEILKE-RELKIYWGTATTGKPHVAY-FVPMSKIADFLK 64

Query: 64  AGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLASE 123
           AG +  I  AD H+++ D +    E++ E+ + Y++  ++  +E +G   +K++F+  ++
Sbjct: 65  AGCEVTILFADLHAYL-DNMKAPWELL-ELRVSYYENVIKAMLESIGVPLEKLKFIKGTD 122

Query: 124 ILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQGVTI 183
              + +Y   V  +S  VT     ++   + +Q+   +  + L+YP +Q  D  Y  V  
Sbjct: 123 YQLSKEYTLDVYRLSSVVTQHDSKKAGAEVVKQVEHPL-LSGLLYPGLQALDEEYLKVDA 181

Query: 184 AHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQF 243
              G+DQRK    A +    L Y   VH                 L  P V  +T     
Sbjct: 182 QFGGIDQRKIFTFAEKYLPALGYSKRVH-----------------LMNPMVPGLTGS--- 221

Query: 244 KEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFREEPT 303
                  KMS S+  S + + D  E++K+KL+KAFC    V  N VL + +H++F  + +
Sbjct: 222 -------KMSSSEEESKIDLLDRKEDVKKKLKKAFCEPGNVENNGVLSFIKHVLFPLK-S 273

Query: 304 EFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYF 358
           EF I R  K+GG+ TYT + +L+KDFA   +HP DLKN+V   L +LL PIRE F
Sbjct: 274 EFVILRDEKWGGNKTYTAYVDLEKDFAAEVVHPGDLKNSVEVALNKLLDPIREKF 328


>gb|AAC82467.1| (AF087021) tyrosyl-tRNA synthetase; tyrosine--tRNA ligase [Bos
           taurus]
           Length = 528
           
 Score =  141 bits (351), Expect = 2e-32
 Identities = 109/355 (30%), Positives = 179/355 (49%), Gaps = 34/355 (9%)

Query: 4   EERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIADFQK 63
           EE+++L+ +   +EVL  E L+ + +    L+ Y G   +G  H+    +  +KIADF K
Sbjct: 8   EEKLSLITRN-LQEVLGEEKLKEILKE-RELKVYWGTATTGKPHVAY-FVPMSKIADFLK 64

Query: 64  AGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLASE 123
           AG +  I  AD H+++ D +    +V+ E+   Y++  ++  +E +G   +K+ F+  ++
Sbjct: 65  AGCEVTILFADLHAYL-DNMKAPWDVL-ELRTSYYENVIKAMLESIGVPLEKLRFIKGTD 122

Query: 124 ILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQGVTI 183
              + +Y   V  +S  VT     ++   + +Q+   +  + L+YP +Q  D  Y  V  
Sbjct: 123 YQLSKEYTLDVYRLSSVVTQHDAKKAGAEVVKQVEHPL-LSGLLYPGLQALDEEYLKVDA 181

Query: 184 AHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQF 243
              G+DQRK    A +    L Y   +H                 L  P V  +T     
Sbjct: 182 QFGGVDQRKIFTFAEKYLPALGYSKRIH-----------------LMNPMVPGLTGS--- 221

Query: 244 KEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFREEPT 303
                  KMS S+  S + + D  E++K+KL+KAFC    V  N VL +  H++F  + +
Sbjct: 222 -------KMSSSEEESKIDLLDRKEDVKKKLKKAFCEPGNVENNGVLAFIRHVLFPLK-S 273

Query: 304 EFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYF 358
           EF I R  K+GG+ TYT + +L+KDFA+  +HP DLKN+V   L +LL PIRE F
Sbjct: 274 EFVILRDEKWGGNKTYTAYLDLEKDFADEVVHPGDLKNSVEVALNKLLDPIREKF 328


>gb|AAF49462.1| (AE003527) CG4561 gene product [Drosophila melanogaster]
           Length = 525
           
 Score =  136 bits (339), Expect = 4e-31
 Identities = 102/335 (30%), Positives = 170/335 (50%), Gaps = 40/335 (11%)

Query: 34  LQHYIGFEISGYIHLGTGLMAGAKIADFQKAGIKTRIFLADWHSWINDKLGGDLEVIQEV 93
           L+ Y G   +G  H+    +  +KIADF KAG +  I  AD H+++ D +     ++ E+
Sbjct: 35  LKIYWGTATTGKPHVAY-FVPMSKIADFLKAGCEVTILFADLHAYL-DNMKAPWSLL-EL 91

Query: 94  ALKYFKVGMEKSIEVMGGDPKKVEFVLASEILENGDYWQTVIDISKNVTLSRVMRSITIM 153
             KY++  ++  +  +G   +K++FV  S+   + +Y   V  +S  VT     ++    
Sbjct: 92  RTKYYEQVIKAMLSSIGVPLEKLKFVKGSDYQLSKEYTLDVYKLSSVVTQHDAKKA---- 147

Query: 154 GRQMGESIDF---AKLIYPMMQVADIFYQGVTIAHAGMDQRKAHVIAIEVAQKLKYHPIV 210
           G ++ + +++   + L+YP +Q  D  Y  V     G+DQRK    + +   +L Y   +
Sbjct: 148 GAEVVKQVEYPLLSGLLYPGLQALDEEYLKVDAQFGGVDQRKIFTFSEKYLPQLGYEKRI 207

Query: 211 HNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQFKEIKAQMKMSKSKPYSAVFIHDSPEEI 270
           H    + P         GL                  A  KMS S+  S + + DSP  +
Sbjct: 208 HFMNPMVP---------GL------------------AGGKMSSSEEDSKIDLLDSPANV 240

Query: 271 KQKLRKAFCPAREVNYNPVLDWAEHIIFR--EEPTEFTIHRPAKFGGDVTYTTFEELKKD 328
           K+KL+KAFC    +  N +L + +H++F   +E   F ++R A+ GGDVT+  +E+L+K 
Sbjct: 241 KKKLKKAFCEPGNIADNGLLSFVKHVLFSLFKEGEGFEVNREAEHGGDVTFLKYEDLEKY 300

Query: 329 FAEGKLHPLDLKNAVAEYLIELLKPIREYFERHPE 363
           +AE KLHP DLK  V +Y+  LL PIR+ FE +PE
Sbjct: 301 YAEDKLHPGDLKATVEKYINRLLDPIRKAFE-NPE 334


>sp|O14055|SYYC_SCHPO TYROSYL-TRNA SYNTHETASE, CYTOPLASMIC (TYROSYL--TRNA LIGASE) (TYRRS)
           >gi|7493542|pir||T41049 tyrosine--tRNA ligase (EC
           6.1.1.1) cytoplasmic - fission yeast
           (Schizosaccharomyces pombe) >gi|3451306|emb|CAA20443.1|
           (AL031324) tyrosyl-trna synthetase cytoplasmic EC
           6.1.1.1 [Schizosaccharomyces pombe]
           Length = 401
           
 Score =  120 bits (299), Expect = 2e-26
 Identities = 100/365 (27%), Positives = 173/365 (47%), Gaps = 38/365 (10%)

Query: 4   EERINLVLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIADFQK 63
           +E+  L+ +   +EVL  + +R +      +  Y G   +G  H G   +   K+ADF K
Sbjct: 6   DEKYELITRN-LQEVLGAKMIREILNE-RDISLYWGSAPTGRPHCGY-FVPMMKLADFLK 62

Query: 64  AGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLASE 123
           AG+   + LAD H+++ D +   +E++Q   ++Y+++ ++  ++ +    +K+ FV+ S 
Sbjct: 63  AGVHVTVLLADVHAFL-DNMKAPMELVQH-RVRYYEIIVKSILKSLNIPIEKLRFVIGSS 120

Query: 124 ILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQGVTI 183
                DY      ++ + T     R+   + +Q+   +  + LIYP MQ  D  Y GV +
Sbjct: 121 YQLKEDYTLDNFRLAASTTEHTARRAGAEVVKQVASPL-LSSLIYPGMQALDEQYLGVDV 179

Query: 184 AHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQF 243
              G+DQRK  V+A EV   L Y    H                 L  P V  +      
Sbjct: 180 QFGGVDQRKIFVMAEEVLPVLGYKKRGH-----------------LMNPMVPSL------ 216

Query: 244 KEIKAQMKMSKSKPYSA-VFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIF---- 298
               A  KMS S   +A + I D P+ + +K+R AFC    V  N  L + +++ F    
Sbjct: 217 ----AGGKMSSSAAANAKIDILDDPKTVNKKIRSAFCEPGVVEENGCLAFLKYVSFPAME 272

Query: 299 REEPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYF 358
               TEF I RP +FGG + + T+EE++K + +  L P DLK  +   +  LL  ++E  
Sbjct: 273 LRGETEFVIDRPEQFGGRMVFKTYEEVEKAYKDLTLSPQDLKLGLESSVNTLLAGVQEQL 332

Query: 359 ERHPE 363
           +++P+
Sbjct: 333 KQYPD 337


>prf||2122232A Tyr-tRNA synthetase [Pneumocystis carinii]
           Length = 370
           
 Score =  110 bits (272), Expect = 3e-23
 Identities = 105/364 (28%), Positives = 174/364 (46%), Gaps = 37/364 (10%)

Query: 10  VLKKPTEEVLTVENLRHLFEVGAPLQHYIGFEISGYIHLGTGLMAGAKIADFQKAGIKTR 69
           ++ +  +EVL  E LR + E    L+ Y G   +G  H G   +   KIADF KA ++  
Sbjct: 14  LITRGLQEVLGAERLRKILEE-RDLKLYWGTSPTGKPHCGY-FVPMIKIADFLKAEVEVT 71

Query: 70  IFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLASEILENGD 129
           I  AD H+++ D L   +++++  A KY++  ++  ++ +G   +K+ FVL S    +  
Sbjct: 72  ILFADIHAFL-DNLKAPIDIVKYRA-KYYEFIIKAILKSIGVSTEKLRFVLGSSYQLSSK 129

Query: 130 YWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQGVTIAHAGMD 189
           Y      +   VT     ++   + +Q+  S+  + L+YP MQ  D  Y        G+D
Sbjct: 130 YCMDNFRLCTIVTEHDAKKAGAEVVKQVENSL-LSGLLYPGMQALDEEYLDSDAQFGGVD 188

Query: 190 QRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQFKEIKAQ 249
           QRK    A       KY P++  G K K + +   ++ GL                  A 
Sbjct: 189 QRKIFTFAE------KYLPML--GLK-KRIHLMSPMIPGL------------------AG 221

Query: 250 MKMSKS-KPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFREEPTE---- 304
            KMS S    + + I D  E +K+K+ KA C    V  N +L+ A+H+IF     +    
Sbjct: 222 GKMSASGNENNKIDILDDAETVKKKINKALCVEAAVENNGLLELAKHVIFPVLALKGIPA 281

Query: 305 FTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIREYFERHPEP 364
            TI+R  K+GG V+Y ++E L+ ++   KL P DLK  +++ L  LL+ IR  F  + E 
Sbjct: 282 LTINREEKWGGPVSYNSYELLELEYVNRKLSPQDLKIGISDSLNFLLESIRLEFAENKEF 341

Query: 365 LELM 368
            E++
Sbjct: 342 QEIL 345


>emb|CAB60885.2| (AL132880) predicted using Genefinder; preliminary prediction
           [Caenorhabditis elegans]
           Length = 540
           
 Score = 92.1 bits (225), Expect = 1e-17
 Identities = 93/354 (26%), Positives = 162/354 (45%), Gaps = 42/354 (11%)

Query: 4   EERINLVLKKPTEEVLTVENLRHLFEVGAPLQH-YIGFEISGYIHLGTGLMAGAKIADFQ 62
           +E   L+L+   +E L V+ L    E    + H Y G   +G  H+G  L+   KIADF 
Sbjct: 17  KETRELILRN-LQESLGVDKLTKQLETPGKVPHVYWGTATTGKPHVGY-LVPMRKIADFL 74

Query: 63  KAGIKTRIFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLAS 122
           +AG+K  I  AD H+++ D +    E+++   + Y  V ++  ++ +    +++ F   +
Sbjct: 75  QAGLKVTILFADLHAYL-DNMKSSWELLKCRVIYYENV-IKALLQSLDVPIEQLYFKKGT 132

Query: 123 EILENGDYWQTVIDISKNVTLSRVMRSITIMGRQMGESIDFAKLIYPMMQVADIFYQGVT 182
           E   + +Y   V+ +S  V+    +++   + +Q+ ES   + L+YP++Q  D  Y  V 
Sbjct: 133 EYQLSREYTDDVLRLSAQVSQRDALKAGAEVVKQV-ESPLLSGLLYPLLQALDEQYLKVD 191

Query: 183 IAHAGMDQRKAHVIAIEVAQKLKYHPIVHNGEKLKPVAVHHHLLLGLQEPPVWPITSEEQ 242
               G+DQRK  ++A E   KLK     H                 L  P V  +T    
Sbjct: 192 GQFGGVDQRKIFILAEEQLPKLKLGKRWH-----------------LMNPMVPGLTG--- 231

Query: 243 FKEIKAQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVNYNPVLDWAEHIIFR-EE 301
                   KMS S+  S + + D PE+++ K+  A C +R+   N VL +   ++F    
Sbjct: 232 -------TKMSSSEEDSKIDVLDEPEKVRSKIMGAAC-SRDQPDNGVLSFYNFVLFPIVS 283

Query: 302 PTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPIR 355
           P    I     F         + LK+ + +GKL    LK  +A++L+ LL+ +R
Sbjct: 284 PNAIEIENQQFF-------DIDSLKRAYLDGKLDENTLKTFLADFLVNLLEKVR 330


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.320    0.139    0.406 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 141220035
Number of Sequences: 2977
Number of extensions: 6077400
Number of successful extensions: 14987
Number of sequences better than 1.0e-10: 22
Number of HSP's better than  0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 14892
Number of HSP's gapped (non-prelim): 28
length of query: 375
length of database: 189,106,746
effective HSP length: 55
effective length of query: 320
effective length of database: 156,189,961
effective search space: 49980787520
effective search space used: 49980787520
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 166 (69.1 bits)