BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1769 (mmdA) DE:methylmalonyl-CoA decarboxylase, subunit alpha (mmdA) (522 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||H75135 methylmalonyl-coa decarboxylase, chain A lpha (mmda)... 1051 0.0 pir||D71074 probable methylmalonyl-CoA decarboxylase alpha chain... 1023 0.0 gi|11499799 methylmalonyl-CoA decarboxylase, subunit alpha (mmdA... 773 0.0 pir||C72344 propionyl-CoA carboxylase, beta subunit - Thermotoga... 698 0.0 dbj|BAB06676.1| (AP001517) methylmalonyl-CoA decarboxylase alpha... 651 0.0 pir||T44982 methylmalonyl-CoA decarboxylase (EC 4.1.1.41) alpha ... 639 0.0 gb|AAK42602.1| Propionyl-CoA carboxylase beta subunit (ppcB) [Su... 624 e-178 gb|AAG19817.1| (AE005066) methylmalonyl-CoA decarboxylase, subun... 621 e-177 pir||T43828 propionyl-CoA carboxylase (EC 6.4.1.3) [validated] -... 616 e-175 pir||T44289 probable methylmalonyl-CoA decarboxylase (EC 4.1.1.4... 612 e-174 pir||H75410 probable propionyl-CoA carboxylase, alpha subunit - ... 609 e-173 pir||A49094 methylmalonyl-CoA decarboxylase (EC 4.1.1.41) alpha ... 607 e-173 pir||D71667 propionyl-COA carboxylase beta chain precursor (pccB... 600 e-170 sp|P53003|PCCB_SACER PROPIONYL-COA CARBOXYLASE BETA CHAIN (PCCAS... 596 e-169 pir||T42208 propionyl-CoA carboxylase complex B chain - Streptom... 596 e-169 pir||T29065 probable methylmalonyl-CoA decarboxylase (EC 4.1.1.4... 583 e-165 sp|P79384|PCCB_PIG PROPIONYL-COA CARBOXYLASE BETA CHAIN, MITOCHO... 562 e-159 pir||T45009 propionyl-CoA carboxylase (EC 6.4.1.3) beta chain pr... 558 e-158 pir||T16428 propionyl-CoA carboxylase (EC 6.4.1.3) beta chain F5... 557 e-157 gi|4557044 propionyl Coenzyme A carboxylase, beta polypeptide [H... 555 e-157 gb|AAD13544.1| (AF080235) decarboxylase homolog [Streptomyces cy... 554 e-157 pir||A53020 propionyl-CoA carboxylase (EC 6.4.1.3) beta chain pr... 553 e-156 pir||A70980 probable accD5 protein - Mycobacterium tuberculosis ... 552 e-156 sp|P54541|PCCB_BACSU PUTATIVE PROPIONYL-COA CARBOXYLASE BETA CHA... 551 e-156 gi|8393913 propionyl Coenzyme A carboxylase, beta polypeptide [R... 550 e-155 sp|P53002|PCCB_MYCLE PROBABLE PROPIONYL-COA CARBOXYLASE BETA CHA... 550 e-155 dbj|BAA33850.1| (AB018531) dtsR2 [Corynebacterium glutamicum] 538 e-152 pir||JC4991 detergent sensitivity rescuer - Corynebacterium glut... 501 e-141 pir||A48665 methylmalonyl-CoA carboxyltransferase (EC 2.1.3.1) 1... 450 e-125 pir||C70887 probable Propionyl-CoA carboxylase - Mycobacterium t... 439 e-122 sp|Q10506|PCCB_MYCTU PROBABLE PROPIONYL-COA CARBOXYLASE BETA CHA... 351 1e-95 pir||T44709 acetyl/propionyl CoA carboxylase [imported] - Mycoba... 344 2e-93 pir||B69893 propionyl-CoA carboxylase homolog yngE - Bacillus su... 343 3e-93 dbj|BAB04855.1| (AP001511) propionyl-CoA carboxylase [Bacillus h... 341 1e-92 gb|AAG19127.1| (AE005010) propionyl-CoA carboxylase homolog; Yng... 332 8e-90 gb|AAF32341.1|AF218939_9 (AF218939) b-propionyl-CoA carboxylase ... 329 4e-89 sp|Q06101|PCCB_RHOER PROPIONYL-COA CARBOXYLASE BETA CHAIN (PCCAS... 327 2e-88 sp|P34385|YLP5_CAEEL HYPOTHETICAL 66.5 KD PROTEIN F02A9.5 IN CHR... 287 2e-76 emb|CAB87213.1| (AL163641) acetyl/propionyl CoA carboxylase, bet... 283 4e-75 gb|AAF35258.1|AF059510_1 (AF059510) 3-methylcrotonyl-CoA carboxy... 277 2e-73 gb|AAG17227.1|AF217984_1 (AF217984) unknown [Homo sapiens] 277 2e-73 pir||F70550 probable accD1 protein - Mycobacterium tuberculosis ... 276 4e-73 gi|11545863 non-biotin containing subunit of 3-methylcrotonyl-Co... 270 4e-71 gb|AAC38045.1| (U94697) propionyl-CoA carboxylase beta chain hom... 269 5e-71 gb|AAF57388.1| (AE003789) CG3267 gene product [Drosophila melano... 266 3e-70 pir||F75382 probable propionyl-CoA carboxylase, beta subunit - D... 264 2e-69 emb|CAA68941.1| (Y07660) B subunit of propionyl-CoA carboxylase ... 259 4e-68 pir||C83395 probable acyl-CoA carboxyltransferase beta chain PA2... 255 8e-67 pir||T05433 hypothetical protein F28A23.210 - Arabidopsis thalia... 253 3e-66 pir||D70719 probable propionyl-CoA carboxylase - Mycobacterium t... 238 9e-62 emb|CAB95891.1| (AL359988) putative acetyl/propionyl CoA carboxy... 238 2e-61 dbj|BAB16296.1| (AB039884) acetyl-CoA carboxylase carboxyltransf... 238 2e-61 pir||C83284 probable biotin-dependent carboxylase PA2888 [import... 235 1e-60 pir||B83471 probable pyruvate carboxylase PA1400 [imported] - Ps... 224 2e-57 pir||C75585 carboxylase - Deinococcus radiodurans (strain R1) >g... 215 1e-54 pir||T45098 probable propionyl-coA carboxylase beta chain [impor... 197 3e-49 gb|AAC69174.1| (AF030576) methylmalonyl-CoA decarboxylase alpha ... 194 2e-48 gb|AAA60036.1| (M13573) propionyl-CoA carboxylase beta chain (EC... 185 1e-45 emb|CAA74219.1| (Y13917) yngE [Bacillus subtilis] 169 9e-41 sp|Q06700|GCDA_ACIFE GLUTACONYL-COA DECARBOXYLASE A SUBUNIT (CAR... 128 2e-28 emb|CAC00930.1| (AL390935) probable propionyl-coa carboxylase be... 108 1e-22 emb|CAA19885.1| (AL031032) putative protein (fragment) [Arabidop... 94 4e-18 pir||H81687 acetyl-coenzyme A carboxylase carboxyl transferase, ... 83 9e-15 gb|AAB97629.1| (AF121266) malonate decarboxylase beta subunit [A... 80 8e-14 pir||C72124 acetyl-coenzyme A carboxylase carboxyl transferase, ... 80 8e-14 emb|CAC00894.1| (AL390935) probable propionyl-coa carboxylase be... 79 1e-13 sp|P08193|ACCD_ECOLI ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRAN... 78 3e-13 pir||B71534 probable accoa carboxylase/transferase beta - Chlamy... 77 5e-13 pir||E71875 acetyl-coenzyme A carboxylase chain B - Helicobacter... 76 9e-13 pir||F64638 acetyl-CoA carboxylase beta subunit - Helicobacter p... 76 1e-12 gb|AAG24832.1| (AF294436) acetyl-CoA carboxylase beta subunit [B... 76 1e-12 pir||S41121 acetyl-CoA carboxylase (EC 6.4.1.2) - human >gi|4523... 75 3e-12 gi|4501855 acetyl-Coenzyme A carboxylase beta [Homo sapiens] >gi... 75 3e-12 pir||A75422 acetyl-CoA carboxylase carboxyl transferase, beta su... 74 3e-12 pir||C53376 hypothetical protein (iaaH 3' region) - Pseudomonas ... 74 5e-12 sp|P48937|ACCD_BRANA ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRAN... 74 5e-12 pir||G81429 acetyl-CoA carboxylase (EC 6.4.1.2) carboxyltransfer... 73 6e-12 gi|11497537 acetyl-coA carboxylase beta subunit [Spinacia olerac... 73 1e-11 pir||T07012 acetyl-CoA carboxylase (EC 6.4.1.2) - potato chlorop... 72 2e-11 gi|11465966 acetyl-CoA carboxylase beta subunit [Nicotiana tabac... 71 3e-11 gb|AAA23965.1| (M68935) acetyl-CoA carboxylase beta subunit [Esc... 71 3e-11 gi|11466711 ORF316 [Marchantia polymorpha] >gi|141629|sp|P12217|... 71 4e-11 pir||I41212 folC expression protein - Escherichia coli >gi|14600... 70 5e-11 gi|7525042 carboxytransferase beta subunit [Arabidopsis thaliana... 69 9e-11 pir||T32413 probable acetyl-CoA carboxylase (EC 6.4.1.2) W09B6.1... 69 9e-11 >pir||H75135 methylmalonyl-coa decarboxylase, chain A lpha (mmda) PAB1769 - Pyrococcus abyssi (strain Orsay) >gi|5458312|emb|CAB49801.1| (AJ248285) methylmalonyl-CoA decarboxylase, subunit a lpha (mmdA) [Pyrococcus abyssi] Length = 522 Score = 1051 bits (2688), Expect = 0.0 Identities = 522/522 (100%), Positives = 522/522 (100%) Query: 1 MGMMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHR 60 MGMMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHR Sbjct: 1 MGMMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHR 60 Query: 61 ATEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA 120 ATEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA Sbjct: 61 ATEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA 120 Query: 121 GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG 180 GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG Sbjct: 121 GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG 180 Query: 181 DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL 240 DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL Sbjct: 181 DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL 240 Query: 241 IKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENG 300 IKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENG Sbjct: 241 IKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENG 300 Query: 301 NPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN 360 NPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN Sbjct: 301 NPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN 360 Query: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSK 420 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSK Sbjct: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSK 420 Query: 421 HLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAA 480 HLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAA Sbjct: 421 HLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAA 480 Query: 481 SRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 SRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL Sbjct: 481 SRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 >pir||D71074 probable methylmalonyl-CoA decarboxylase alpha chain - Pyrococcus horikoshii >gi|3257707|dbj|BAA30390.1| (AP000005) 522aa long hypothetical methylmalonyl-CoA decarboxylase alpha chain [Pyrococcus horikoshii] Length = 522 Score = 1023 bits (2617), Expect = 0.0 Identities = 503/522 (96%), Positives = 518/522 (98%) Query: 1 MGMMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHR 60 MGM+EKVE+L++R+KKILQMGGEEAIKKQH+KGKLTARER+ELLLDPGSFVEIGMFVKHR Sbjct: 1 MGMIEKVEELHERKKKILQMGGEEAIKKQHEKGKLTARERLELLLDPGSFVEIGMFVKHR 60 Query: 61 ATEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA 120 ATEFGMDKR+LPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA Sbjct: 61 ATEFGMDKRELPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA 120 Query: 121 GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG 180 GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG Sbjct: 121 GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG 180 Query: 181 DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL 240 DFILMVDNPSTFMFITGPQVVKAVTGV+VTPVQLGGA+VHAQ+SGQAHLIGKSDEEVI L Sbjct: 181 DFILMVDNPSTFMFITGPQVVKAVTGVEVTPVQLGGAMVHAQRSGQAHLIGKSDEEVIML 240 Query: 241 IKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENG 300 IK+LLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNK YDVRQVIY IVDRDENG Sbjct: 241 IKKLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKGYDVRQVIYTIVDRDENG 300 Query: 301 NPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN 360 NPDFLELQPYFAPNAVIGFGRINGQ VGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN Sbjct: 301 NPDFLELQPYFAPNAVIGFGRINGQPVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN 360 Query: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSK 420 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVT+ILRKAYGGAYLAMGSK Sbjct: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTIILRKAYGGAYLAMGSK 420 Query: 421 HLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAA 480 HLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFR+QKIQEYREKFANPYVAA Sbjct: 421 HLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRRQKIQEYREKFANPYVAA 480 Query: 481 SRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 +RGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL Sbjct: 481 ARGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 >gi|11499799 methylmalonyl-CoA decarboxylase, subunit alpha (mmdA) [Archaeoglobus fulgidus] >gi|7438114|pir||A69527 methylmalonyl-CoA decarboxylase, subunit alpha (mmdA) homolog - Archaeoglobus fulgidus >gi|2648306|gb|AAB89035.1| (AE000952) methylmalonyl-CoA decarboxylase, subunit alpha (mmdA) [Archaeoglobus fulgidus] Length = 516 Score = 773 bits (1974), Expect = 0.0 Identities = 370/518 (71%), Positives = 437/518 (83%), Gaps = 5/518 (0%) Query: 5 EKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEF 64 E VE+LY +++KI QMGG+E I++QH++GKLTARERIELLLDPGSFVEI FV+ R T+F Sbjct: 4 ELVEELYGKKEKIRQMGGKERIERQHEQGKLTARERIELLLDPGSFVEINPFVEKRNTDF 63 Query: 65 GMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPV 124 G+DK DLPADGV+TGYGT++GR V V+AQDFTVMGGSLGEMH KI I++ A++ G PV Sbjct: 64 GLDKMDLPADGVVTGYGTVDGRPVAVFAQDFTVMGGSLGEMHGFKIAYILDFAMKLGIPV 123 Query: 125 IGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFIL 184 +GLNDSGGARIQEGVD+LKGYG+IF NT+ SGV+PQI+ IMGPCAGGAVYSPAIGDFI+ Sbjct: 124 VGLNDSGGARIQEGVDALKGYGDIFYRNTLASGVIPQISVIMGPCAGGAVYSPAIGDFIV 183 Query: 185 MVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRL 244 M NP+ +MFITGPQV+K VTG +V+ LGG HA KSG HL+ + D + + L++RL Sbjct: 184 MTKNPNCYMFITGPQVIKTVTGEEVSAFDLGGWQAHAMKSGNCHLVAEDDRDAMMLVRRL 243 Query: 245 LSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDF 304 LSYLP NNME PP VK D+P R TPE+YD++PDDP K YDVR VI A+VD N + Sbjct: 244 LSYLPLNNMEDPPVVKTGDDPVRLTPEIYDVLPDDPQKPYDVRDVITAVVD-----NGEL 298 Query: 305 LELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIV 364 LE+ PY+APNAV+GF RI+G++VGIVANNP H AG LD+DSSDKIARFVRFCDAFNIPI+ Sbjct: 299 LEIHPYYAPNAVVGFARIDGKSVGIVANNPRHFAGCLDVDSSDKIARFVRFCDAFNIPII 358 Query: 365 TFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGA 424 TFVDVPGYLPGV QE GIIRHGAKVLYAY+EATVP+VT+ILRKAYGGAYLAMGSKHLGA Sbjct: 359 TFVDVPGYLPGVQQEYGGIIRHGAKVLYAYSEATVPLVTIILRKAYGGAYLAMGSKHLGA 418 Query: 425 DFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGY 484 D V+A+PTAEIAVMGPEGAA I+FRKEI AE+P+ R++KI+EYREKFANPY AA+RGY Sbjct: 419 DIVYAYPTAEIAVMGPEGAAEIVFRKEIKAAEDPKAMREEKIREYREKFANPYRAAARGY 478 Query: 485 IDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 IDD+IDP TR K+V AL LE+KR KLPPKKHGNIPL Sbjct: 479 IDDIIDPKYTRVKVVSALRILESKREKLPPKKHGNIPL 516 >pir||C72344 propionyl-CoA carboxylase, beta subunit - Thermotoga maritima (strain MSB8) >gi|4981240|gb|AAD35798.1|AE001742_13 (AE001742) propionyl-CoA carboxylase, beta subunit [Thermotoga maritima] Length = 515 Score = 698 bits (1781), Expect = 0.0 Identities = 349/522 (66%), Positives = 413/522 (78%), Gaps = 7/522 (1%) Query: 1 MGMMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHR 60 M + +K+E+L + K+I Q GG E ++KQH GKLTA ER+ELLLDPG+FVEI FV+HR Sbjct: 1 MSLRDKIEELKKIEKEIEQGGGPEKVEKQHRAGKLTAWERLELLLDPGTFVEIDKFVEHR 60 Query: 61 ATEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA 120 T FG+DK LP DGVITG G INGR V V++QDFTVMGGSLGEMHA KI ++++LAL+ Sbjct: 61 NTYFGLDKVKLPRDGVITGVGEINGRKVAVFSQDFTVMGGSLGEMHAKKIVKLLDLALKM 120 Query: 121 GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG 180 G PVIG+NDSGGARIQEGVD+L GYGEIF NT+ SGVVPQIT I GPCAGGAVYSPA+ Sbjct: 121 GIPVIGINDSGGARIQEGVDALAGYGEIFLRNTLASGVVPQITVIAGPCAGGAVYSPALT 180 Query: 181 DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL 240 DFI+MVD + MFITGP V+KAVTG +++ LGGA+VH QKSG AH + +DE+ + L Sbjct: 181 DFIVMVDQTAR-MFITGPNVIKAVTGEEISQEDLGGAMVHNQKSGNAHFLADNDEKAMSL 239 Query: 241 IKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENG 300 ++ LLSYLPSNN E+PP V+ D ++ DI+PD+PNK YDVR VI +VD E Sbjct: 240 VRTLLSYLPSNNAEEPP-VEDPDTSLETPEDILDILPDNPNKGYDVRDVIKRVVDHGE-- 296 Query: 301 NPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN 360 F E+QPYFA N VIGF RI G+TVGIVAN P LAGVLDIDSSDK ARF+RF DAFN Sbjct: 297 ---FFEVQPYFAKNIVIGFARIQGKTVGIVANQPSVLAGVLDIDSSDKAARFIRFLDAFN 353 Query: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSK 420 IPI+TFVD PGYLPGV QE GIIRHGAK+LYAY+EATVP +TVILRKAYGGAY+AMGSK Sbjct: 354 IPILTFVDTPGYLPGVAQEHGGIIRHGAKLLYAYSEATVPKITVILRKAYGGAYIAMGSK 413 Query: 421 HLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAA 480 HLGAD V AWP+AEIAVMGPEGAANIIF++EI + NPEE R++ I+EY+++FANPY+AA Sbjct: 414 HLGADMVLAWPSAEIAVMGPEGAANIIFKREIEASSNPEETRRKLIEEYKQQFANPYIAA 473 Query: 481 SRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 SRGY+D VIDP ETR I+ ALE E K P KKHGNIPL Sbjct: 474 SRGYVDMVIDPRETRKYIMRALEVCETKVEYRPKKKHGNIPL 515 >dbj|BAB06676.1| (AP001517) methylmalonyl-CoA decarboxylase alpha subunit [Bacillus halodurans] Length = 516 Score = 651 bits (1662), Expect = 0.0 Identities = 325/527 (61%), Positives = 400/527 (75%), Gaps = 16/527 (3%) Query: 1 MGMMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHR 60 M M +++ ++ RR K+ GG + I QHD+GKLTARERI+LLLD G+FVE+ F++HR Sbjct: 1 MDMFDRIHEMEVRRDKVKLGGGSKRIDAQHDRGKLTARERIDLLLDEGTFVELNPFIEHR 60 Query: 61 ATEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA 120 +FG + P +GV+TGYG ++GRLVF++AQDFTV GG+LGEMHA KI ++M+LA E Sbjct: 61 GLDFGT--AEAPGEGVVTGYGKVDGRLVFLFAQDFTVFGGALGEMHARKITKVMDLAAEN 118 Query: 121 GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG 180 GAP++GLNDSGGARIQEGV SL GYGEIF N+I SGV+PQI+ I+GPCAGGAVYSPAI Sbjct: 119 GAPIVGLNDSGGARIQEGVRSLDGYGEIFYRNSIYSGVIPQISVILGPCAGGAVYSPAIT 178 Query: 181 DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL 240 DF+ MV+ S MFITGP+V+++VTG + LGGA VH+ SG AH S+E V+ Sbjct: 179 DFVFMVEKTSQ-MFITGPKVIESVTGAKINSEDLGGAKVHSTISGNAHFTAASEEGVLQQ 237 Query: 241 IKRLLSYLPSNNMEKPPRVK-----PKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVD 295 ++ LLSYLPS+ EKPP + P DE R EL DIVP D K YDVR VI +VD Sbjct: 238 VRNLLSYLPSSFEEKPPHQRAKHPVPLDE---RVQELLDIVPVDGTKVYDVRHVIEKVVD 294 Query: 296 RDENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRF 355 ++ FLE+QP FA N V+GF RING TVGI+ANNP +AG LDI+SSDK ARF+RF Sbjct: 295 DEQ-----FLEVQPQFARNIVVGFARINGDTVGIIANNPKMMAGGLDINSSDKCARFIRF 349 Query: 356 CDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYL 415 CD FNIP++TF DV G++PGV QE GIIRHGAK+LYAY+EATVP +TVILRKAYGGAY+ Sbjct: 350 CDCFNIPLITFEDVSGFIPGVQQEHGGIIRHGAKILYAYSEATVPKITVILRKAYGGAYV 409 Query: 416 AMGSKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFAN 475 A+ SK +GAD VFAWP AE+AVMGPEGAANIIF KEI ++ NP+ R+ KI EYRE+FAN Sbjct: 410 ALNSKAIGADLVFAWPNAELAVMGPEGAANIIFAKEIKESANPDATRQAKISEYRERFAN 469 Query: 476 PYVAASRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 PYVAA+ G IDDVIDP +TR +V AL L+NK+ LP KKHGNIPL Sbjct: 470 PYVAAANGMIDDVIDPRDTRKSLVSALAMLKNKKKTLPKKKHGNIPL 516 >pir||T44982 methylmalonyl-CoA decarboxylase (EC 4.1.1.41) alpha chain [validated] - Propionigenium modestum (fragment) >gi|2706398|emb|CAA05137.1| (AJ002015) methylmalonyl-CoA decarboxylase, alpha-subunit [Propionigenium modestum] Length = 512 Score = 639 bits (1630), Expect = 0.0 Identities = 316/518 (61%), Positives = 397/518 (76%), Gaps = 6/518 (1%) Query: 5 EKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEF 64 +K++DL ++++KI GG + I+KQH GK+TARER+ L D G+FVE+ FV+HR T F Sbjct: 1 KKIQDLQKKKEKIALGGGIKRIEKQHASGKMTARERLAYLFDEGTFVEMDAFVQHRCTNF 60 Query: 65 GMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPV 124 GMDK+DLP++ V+TGYG ++GR+V+ ++QDFTV GG+LGEMHA KI + M++A + GAPV Sbjct: 61 GMDKQDLPSESVVTGYGMVDGRVVYAFSQDFTVTGGALGEMHAKKICKAMDMAGKVGAPV 120 Query: 125 IGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFIL 184 +GLNDSGGARIQE VD+L GYG+IF N+I SGVVPQI+AI+GPCAGGAVYSPA+ DFI Sbjct: 121 VGLNDSGGARIQEAVDALSGYGDIFYRNSIYSGVVPQISAILGPCAGGAVYSPALTDFIF 180 Query: 185 MVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRL 244 MVD S MFITGPQV+K VTG +VT QLGGA+ H SG A I + D+ I I+RL Sbjct: 181 MVDQTSQ-MFITGPQVIKTVTGEEVTAEQLGGAMTHNSTSGCAQFISQDDKACIDDIRRL 239 Query: 245 LSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDF 304 +S+LPSNNMEK P +D+ + PEL ++PD+PNKAY++ VI IVD N D+ Sbjct: 240 ISFLPSNNMEKAPEFGCEDDLNIQFPELDALMPDNPNKAYNMFDVITKIVD-----NGDY 294 Query: 305 LELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIV 364 +E QP+++ N + F R+NG++VGI+AN P +AG LDIDS DK A+F+R CDAFNIP++ Sbjct: 295 MEYQPHYSKNIITCFARVNGKSVGIIANQPQVMAGCLDIDSGDKCAKFIRTCDAFNIPLL 354 Query: 365 TFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGA 424 T VDVPG+LPGV QE GIIRHGAK+LYAY+EATVP VT+I RKAYGGAY+AM SK LGA Sbjct: 355 TIVDVPGFLPGVTQEYGGIIRHGAKILYAYSEATVPKVTLITRKAYGGAYVAMCSKSLGA 414 Query: 425 DFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGY 484 D V AWPTAEIAVMGP GA NIIFRK+I A++P KQK+ EY +FANPY AA RG Sbjct: 415 DVVLAWPTAEIAVMGPAGAVNIIFRKDIKDAKDPAATTKQKLDEYTTEFANPYQAARRGL 474 Query: 485 IDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 +DDVI+P +R +IV A LE KR KLP KKHGNIPL Sbjct: 475 VDDVIEPKTSRQRIVDAFNMLEGKREKLPAKKHGNIPL 512 >gb|AAK42602.1| Propionyl-CoA carboxylase beta subunit (ppcB) [Sulfolobus solfataricus] Length = 523 Score = 624 bits (1592), Expect = e-178 Identities = 305/520 (58%), Positives = 381/520 (72%), Gaps = 5/520 (0%) Query: 3 MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRAT 62 M + +EDL ++K+ + GGEE I QH KGKLTARER+ L D G F EI F RAT Sbjct: 9 MDKLIEDLKILKEKVYKGGGEEKINFQHGKGKLTARERLNQLFDEGKFNEILTFATTRAT 68 Query: 63 EFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGA 122 EFG+DK DGVI G+G I+GR VF YAQDFT++GGSLGE HA KI R ELAL+ GA Sbjct: 69 EFGLDKNRFYGDGVIAGWGKIDGRQVFAYAQDFTILGGSLGETHANKIVRAYELALKVGA 128 Query: 123 PVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDF 182 PVIG+NDSGGARIQEG SL+GYG +FKMN + SGV+PQIT + GP AGGAVYSPA+ DF Sbjct: 129 PVIGINDSGGARIQEGALSLEGYGAVFKMNVMASGVIPQITIMAGPAAGGAVYSPALTDF 188 Query: 183 ILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIK 242 ++M+ + +MF+TGP++ K G +V+ LGGA++HA KSG H + +++++ I + K Sbjct: 189 LIMIKGDAYYMFVTGPEITKVSIGEEVSYQDLGGAIIHATKSGVVHFVAENEQDAINITK 248 Query: 243 RLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNP 302 RLLSYLPSNNME+PP V D R IVP D K +D+R +IY IVD N Sbjct: 249 RLLSYLPSNNMEEPPYVDTGDPADRAVQSAESIVPTDSVKPFDIRDLIYNIVD-----NS 303 Query: 303 DFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIP 362 +FLE+ +A N +GFGRING VGIVANN + G +DID++DK ARF+RFCDAFNIP Sbjct: 304 EFLEVHKLWAQNITVGFGRINGNVVGIVANNSAYYGGAIDIDAADKAARFIRFCDAFNIP 363 Query: 363 IVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHL 422 +++ VD PGY+PG DQE +GIIRHGAK+LYA+AEATVP +TVI+R++YGGA++AM K L Sbjct: 364 VISLVDTPGYVPGTDQEYKGIIRHGAKMLYAFAEATVPKITVIVRRSYGGAHIAMSIKSL 423 Query: 423 GADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASR 482 GAD V+AWP+AEIAV GPEGA I++R+EI A+NPEE KQKI EY++ FANPY AA + Sbjct: 424 GADLVYAWPSAEIAVTGPEGAVRILYRREIQSAQNPEELLKQKITEYKKLFANPYWAAEK 483 Query: 483 GYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 G IDDVI+P +TR I LE L NKR PKKHGNIPL Sbjct: 484 GLIDDVIEPKDTRNVIARGLEMLRNKREFRYPKKHGNIPL 523 >gb|AAG19817.1| (AE005066) methylmalonyl-CoA decarboxylase, subunit alpha; MmdA [Halobacterium sp. NRC-1] Length = 516 Score = 621 bits (1583), Expect = e-177 Identities = 306/522 (58%), Positives = 388/522 (73%), Gaps = 6/522 (1%) Query: 1 MGMMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHR 60 M M E++EDL ++ ++ L GGE I+ QH+KGKLTARERI+ LD G+F E+ HR Sbjct: 1 MTMEERIEDLREQTERALLGGGEARIESQHEKGKLTARERIDYFLDDGTFNELDQLRTHR 60 Query: 61 ATEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA 120 +T F MD+ LP DGV+TGYG +NGR FV+A DFTV GGSLGE+ A K+ ++M+ A+E Sbjct: 61 STNFDMDETKLPGDGVVTGYGDVNGRTTFVFAHDFTVFGGSLGEVFAEKVTKVMDRAMEV 120 Query: 121 GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG 180 GAPV+GLNDS GARIQEGVD+L G+ EIF N SGVVPQI+AIMGPCAGGAVYSPAI Sbjct: 121 GAPVVGLNDSAGARIQEGVDALGGFAEIFTRNEKASGVVPQISAIMGPCAGGAVYSPAIT 180 Query: 181 DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL 240 DF +MV + S MFITGP V++ VTG V +LGGA HA +SG AH S+E + Sbjct: 181 DFTVMVKDTS-HMFITGPDVIETVTGEQVGFEELGGATTHAAESGVAHFACDSEEAALDN 239 Query: 241 IKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENG 300 IKRLLSYLP NN+E PPRV+P D+P RR L IVPD+P K YD+ V+ ++VD Sbjct: 240 IKRLLSYLPQNNVEDPPRVEPYDDPERRDDALETIVPDEPRKPYDMTDVVDSVVDEQS-- 297 Query: 301 NPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN 360 F E+Q +A N V+GF R++G++VGIVAN P AG LDID+S+K +RFVRFCD+FN Sbjct: 298 ---FFEVQADYAKNIVVGFARLDGRSVGIVANQPRVNAGTLDIDASEKGSRFVRFCDSFN 354 Query: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSK 420 +PI+T VDVPG+LPG DQE GIIRHGAK+LYA++EA+VP++TVI RKAYGGAY M SK Sbjct: 355 VPILTLVDVPGFLPGTDQEHGGIIRHGAKLLYAFSEASVPLMTVITRKAYGGAYDVMASK 414 Query: 421 HLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAA 480 H+GAD +AWPTAEIAVMGP+GA N+++ E+ A++ R++ I EYRE+FANPY AA Sbjct: 415 HIGADVNYAWPTAEIAVMGPKGAVNVLYSDELEAADDTAARRQELIDEYREEFANPYTAA 474 Query: 481 SRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 RGY+D VI+P ETR +++ L+ L +KR + P KKHGNIPL Sbjct: 475 DRGYLDAVIEPTETRPRLIDDLDMLASKREETPDKKHGNIPL 516 >pir||T43828 propionyl-CoA carboxylase (EC 6.4.1.3) [validated] - Myxococcus xanthus >gi|2627219|dbj|BAA23583.1| (AB007000) propionyl-CoA carboxylase [Myxococcus xanthus] Length = 524 Score = 616 bits (1571), Expect = e-175 Identities = 316/506 (62%), Positives = 380/506 (74%), Gaps = 10/506 (1%) Query: 21 GGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGMDKRDLPADGVITGY 80 GG + I KQH+ GKLTARERI+LLLDPGSF E+ FV HR++EFGM + +P GV+TGY Sbjct: 25 GGADRIAKQHESGKLTARERIDLLLDPGSFCELDKFVTHRSSEFGMGDKKIPGHGVVTGY 84 Query: 81 GTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVD 140 GT+ GR VFV+AQDFTV GGSL +A KI +IM+LA GAPVIGLNDSGGARIQEGV+ Sbjct: 85 GTVEGRKVFVFAQDFTVFGGSLSGAYAQKICKIMDLATRVGAPVIGLNDSGGARIQEGVE 144 Query: 141 SLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFMFITGPQV 200 SL GY +IF NT SGVVPQI+ IMGPCAGGAVYSPAI DFI+MV + S +MFITGP V Sbjct: 145 SLAGYADIFVRNTGCSGVVPQISLIMGPCAGGAVYSPAITDFIMMVKDTS-YMFITGPDV 203 Query: 201 VKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSNNMEKPPRVK 260 +K VT +V+ LGGA+ H QKSG AH ++++ I + + LLS+LPSNN E+ P Sbjct: 204 IKTVTHEEVSKEALGGAVTHNQKSGVAHFAAENEQAAIVMTRELLSFLPSNNQEEAPVQP 263 Query: 261 PKDEPFR-RTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIGF 319 +D+ FR R IVP +PNK YD+++VI AIVD + F E+Q +FA N VIGF Sbjct: 264 CEDDAFRGRRSRSRTIVPSNPNKPYDIKEVIKAIVD-----DKHFFEVQEHFAKNIVIGF 318 Query: 320 GRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPGYLPGVDQE 379 R+NG+TVG+VAN P LAGVLDID+S K ARFVRFCD FNIP+VT VDVPG+LPG DQE Sbjct: 319 ARMNGRTVGVVANQPAVLAGVLDIDASIKAARFVRFCDCFNIPLVTLVDVPGFLPGTDQE 378 Query: 380 SRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADF---VFAWPTAEIA 436 GII HGAK+LYAYAEATVP VTVI RKAYGGAY M SKH+ AD FAWPTAEIA Sbjct: 379 WGGIITHGAKLLYAYAEATVPKVTVITRKAYGGAYDVMASKHIRADMNFANFAWPTAEIA 438 Query: 437 VMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYIDDVIDPAETRA 496 VMGPEGA NIIFR E+AKA + R + +YR+KFA P+ AA GYID++I P ETRA Sbjct: 439 VMGPEGAVNIIFRNELAKAPDAAAERARLTADYRDKFATPFKAAELGYIDEIIRPEETRA 498 Query: 497 KIVMALEALENKRVKLPPKKHGNIPL 522 K++ +LE L++KR + P+KHGNIPL Sbjct: 499 KLIRSLELLKDKRQENLPRKHGNIPL 524 >pir||T44289 probable methylmalonyl-CoA decarboxylase (EC 4.1.1.41) [imported] - Sulfolobus metallicus >gi|2792514|gb|AAB97083.1| (AF042099) putative carboxyl transferase [Sulfolobus metallicus] Length = 517 Score = 612 bits (1561), Expect = e-174 Identities = 293/514 (57%), Positives = 383/514 (74%), Gaps = 5/514 (0%) Query: 3 MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRAT 62 M + +E++ + K + GGE+ IK QH+KGK+TARERI LL D G+F EI F + ++T Sbjct: 1 MDKLIEEMKSLKAKAMAGGGEDKIKAQHEKGKMTARERIALLFDEGTFSEIMTFARTQST 60 Query: 63 EFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGA 122 EFG+DK DL DGV+TG+G I+GR FVY+QDFT +GG+LGEMHA KI ++ ELAL+ GA Sbjct: 61 EFGLDKTDLYGDGVVTGWGKIDGRTAFVYSQDFTSLGGTLGEMHASKIGKVYELALKVGA 120 Query: 123 PVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDF 182 PVIG+NDSGGARIQEG SL+GYG +FK N + SGV+PQIT + GP AGGAVYSPA+ DF Sbjct: 121 PVIGINDSGGARIQEGAASLEGYGLVFKNNVMASGVIPQITIMAGPAAGGAVYSPALTDF 180 Query: 183 ILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIK 242 ++MV + +MF+TGP++ K V G DV+ LGGA+VHA KSG H + S++E I K Sbjct: 181 LIMVKGDAYYMFVTGPEITKVVLGEDVSMQDLGGAVVHASKSGVVHFMVDSEQEAINTAK 240 Query: 243 RLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNP 302 RLLSYLPSNNME+PP + D R + IVP D K +D+R ++YA+VD N Sbjct: 241 RLLSYLPSNNMEEPPYMDTGDTNDREVKDAESIVPTDSAKTFDIRDLVYAVVD-----NG 295 Query: 303 DFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIP 362 +FLE+ ++A N +GF R+ G VGIVANN + +G +DID++DK ARF+RFCDAFNIP Sbjct: 296 EFLEVHKHWAQNITVGFARVAGNVVGIVANNSAYASGAIDIDAADKAARFIRFCDAFNIP 355 Query: 363 IVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHL 422 +V+ VD PGY+PG DQE RGIIRHGAK+LYA+AEATVP +TV++R++YGGA++AM K L Sbjct: 356 LVSIVDTPGYIPGTDQEYRGIIRHGAKMLYAFAEATVPKITVVVRRSYGGAHIAMSIKSL 415 Query: 423 GADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASR 482 GAD ++AWP+AEIAV GPEGA I+++KE+ A NP+E KQ+I EY++ FANPY AA + Sbjct: 416 GADVIYAWPSAEIAVTGPEGAVRILYKKELQAASNPDELLKQRIAEYKKLFANPYWAAKK 475 Query: 483 GYIDDVIDPAETRAKIVMALEALENKRVKLPPKK 516 G IDDVI+P +TR I+ AL L+NKR PKK Sbjct: 476 GLIDDVIEPKDTRKVIMSALSMLKNKREYRYPKK 509 >pir||H75410 probable propionyl-CoA carboxylase, alpha subunit - Deinococcus radiodurans (strain R1) >gi|6459066|gb|AAF10887.1|AE001978_7 (AE001978) propionyl-CoA carboxylase, alpha subunit, putative [Deinococcus radiodurans] Length = 520 Score = 609 bits (1553), Expect = e-173 Identities = 315/521 (60%), Positives = 388/521 (74%), Gaps = 9/521 (1%) Query: 3 MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRAT 62 + E + + QRR+K+ + GG E +KQ + GKLTARERIE LLDPGSF+E FV+H Sbjct: 8 LQELIATMEQRRRKVEEGGGPERQQKQREGGKLTARERIERLLDPGSFLESSTFVEHGRN 67 Query: 63 EFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGA 122 MD + P +GV+TG GTI+GR VFV++QDFTV+GGSLG+M+A K+ +IM+LA + G Sbjct: 68 RL-MDGIEAPGEGVVTGSGTIDGRQVFVFSQDFTVLGGSLGKMNASKVTKIMDLAAKTGC 126 Query: 123 PVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDF 182 PVIGLNDS GARIQEGVDSL GYGEIF N + SG VPQI+AI+GPCAGGAVYSPAI DF Sbjct: 127 PVIGLNDSAGARIQEGVDSLSGYGEIFYRNAVYSGSVPQISAILGPCAGGAVYSPAITDF 186 Query: 183 ILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIK 242 ILM S++MFITGP+V+K+VT +VT QLGGA VH +KSG AHL + DE VI IK Sbjct: 187 ILM-SRGSSYMFITGPEVIKSVTREEVTFDQLGGADVHTRKSGVAHLAYEGDEAVIDGIK 245 Query: 243 RLLSYLPSNNMEKPPRVKPKDEPF-RRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGN 301 LL YLP N EK P VKP +P RR +L DIV D + Y ++ VI +VD + Sbjct: 246 DLLGYLPQNAREKAP-VKPTSDPADRRNEKLLDIVTPDQRRPYAMQDVIRELVD-----D 299 Query: 302 PDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNI 361 FLE+QP +A N ++GF R+NGQ+VGIVANNP L+G L+ID+SDK ARF+R CD +N+ Sbjct: 300 GTFLEIQPDWAKNIIVGFARLNGQSVGIVANNPKALSGSLNIDASDKAARFIRTCDCYNV 359 Query: 362 PIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKH 421 PI+T VDV G+LPGV QE GIIRHGAK+LYAYAEATVP VT+I RK+YGGAYLAM S+ Sbjct: 360 PILTLVDVSGFLPGVQQEYGGIIRHGAKMLYAYAEATVPKVTLITRKSYGGAYLAMNSRD 419 Query: 422 LGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAAS 481 +GAD V+AWPTA +AVMG EGAANI++RK+I +ENP R +KI EY+E F NPYVAA+ Sbjct: 420 MGADVVYAWPTATVAVMGAEGAANIVYRKDIKDSENPAATRAEKIAEYKEAFDNPYVAAA 479 Query: 482 RGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 +GYIDDVI ETR +++ E L NK P KKHGNIPL Sbjct: 480 KGYIDDVIPMEETRERLIRTFEMLANKEETRPFKKHGNIPL 520 >pir||A49094 methylmalonyl-CoA decarboxylase (EC 4.1.1.41) alpha chain - Veillonella parvula >gi|415593|gb|AAC36820.1| (L22208) methylmalonyl-CoA decarboxylase alpha-subunit [Veillonella parvula] >gi|415915|emb|CAA80872.1| (Z24754) alpha-subunit,methylmalonyl-CoA decarboxylase [Veillonella parvula] Length = 509 Score = 607 bits (1549), Expect = e-173 Identities = 300/520 (57%), Positives = 385/520 (73%), Gaps = 14/520 (2%) Query: 3 MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRAT 62 + EK+E L+++ K+ GGE+ ++KQH +GK+TARER+ L D SFVE+ FVKHR Sbjct: 4 VQEKIELLHEKLAKVKAGGGEKRVEKQHAQGKMTARERLAKLFDDNSFVELDQFVKHRCV 63 Query: 63 EFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGA 122 FG +K++LP +GV+TGYGTI+GRLV+ +AQDFTV GGSLGEMHA KI ++ LA++ GA Sbjct: 64 NFGQEKKELPGEGVVTGYGTIDGRLVYAFAQDFTVEGGSLGEMHAAKIVKVQRLAMKMGA 123 Query: 123 PVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDF 182 P++G+NDSGGARIQE VD+L GYG+IF NT SGV+PQI+ IMGPCAGGAVYSPA+ DF Sbjct: 124 PIVGINDSGGARIQEAVDALAGYGKIFFENTNASGVIPQISVIMGPCAGGAVYSPALTDF 183 Query: 183 ILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIK 242 I MV N S MFITGP V+K+VTG +VT LGGA+ H SG AH +++++ I I+ Sbjct: 184 IYMVKNTSQ-MFITGPAVIKSVTGEEVTAEDLGGAMAHNSVSGVAHFAAENEDDCIAQIR 242 Query: 243 RLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNP 302 LL +LPSNNME P V D+P R L ++PD+ N YD++ VI A VD N Sbjct: 243 YLLGFLPSNNMEDAPLVDTGDDPTREDESLNSLLPDNSNMPYDMKDVIAATVD-----NG 297 Query: 303 DFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIP 362 ++ E+QP++A N + F R +GQ+VGI+AN P +AG LDI++SDK +RF+RFCDAFNIP Sbjct: 298 EYYEVQPFYATNIITCFARFDGQSVGIIANQPKVMAGCLDINASDKSSRFIRFCDAFNIP 357 Query: 363 IVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHL 422 IV FVDVPG+LPG +QE GIIRHGAK+LYAY+EATVP +TVI RKAYGG+YLAM S+ L Sbjct: 358 IVNFVDVPGFLPGTNQEWGGIIRHGAKMLYAYSEATVPKITVITRKAYGGSYLAMCSQDL 417 Query: 423 GADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASR 482 GAD V+AWPT+EIAVMGP GAANIIF+K +E + K +Y E+FA PY AA R Sbjct: 418 GADQVYAWPTSEIAVMGPAGAANIIFKK--------DEDKDAKTAKYVEEFATPYKAAER 469 Query: 483 GYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 G++D VI+P +TR ++ AL L +KR PKKHGNIPL Sbjct: 470 GFVDVVIEPKQTRPAVINALAMLASKRENRAPKKHGNIPL 509 >pir||D71667 propionyl-COA carboxylase beta chain precursor (pccB) RP619 - Rickettsia prowazekii >gi|3861162|emb|CAA15062.1| (AJ235272) PROPIONYL-COA CARBOXYLASE BETA CHAIN PRECURSOR (pccB) [Rickettsia prowazekii] Length = 514 Score = 600 bits (1530), Expect = e-170 Identities = 307/516 (59%), Positives = 374/516 (71%), Gaps = 13/516 (2%) Query: 9 DLYQRRKKILQMGGEEA-IKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGMD 67 +L RK I + GG EA I QH KGKLTARERIE+LLDP SF E GMFV HR FGM Sbjct: 10 ELLDERKNIARQGGGEARINAQHQKGKLTARERIEVLLDPNSFTETGMFVSHRCDNFGMQ 69 Query: 68 KRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGL 127 + DGV+TGYGTINGRLVF+Y+QDFTV+GGSLGE HA KI I++ A+ GAPVIG+ Sbjct: 70 NKKFLGDGVVTGYGTINGRLVFIYSQDFTVLGGSLGEYHAKKICDIIDQAIATGAPVIGI 129 Query: 128 NDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVD 187 NDSGGARIQEGVD+L GYGE+F+ N + SGV+PQIT IMGPCAGGAVYSPA+ DFI MV Sbjct: 130 NDSGGARIQEGVDALAGYGELFQRNVLASGVIPQITLIMGPCAGGAVYSPALTDFIFMVK 189 Query: 188 NPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSY 247 N S++MF+TGP VVK VTG +VT +LGGA +H KSG A L +D E + I++ ++ Sbjct: 190 N-SSYMFVTGPDVVKTVTGEEVTQEKLGGARMHTTKSGVADLAFNNDIEALLEIRKFFNF 248 Query: 248 LPSNNMEKPPRVKPKDEPFRRTP-ELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLE 306 LPS+N P V+P +P R L ++P+ PNK YD+++++ IVD E F E Sbjct: 249 LPSSNRSTLP-VRPTVDPADRVDMSLSTLIPNTPNKPYDMKELVERIVDEGE-----FFE 302 Query: 307 LQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTF 366 LQP FA N +IGFG + G VG +AN P+HLAG LDI++S K ARF+RFCDAFNI IV+ Sbjct: 303 LQPDFAKNIIIGFGYMEGYPVGFIANQPLHLAGCLDINASRKAARFIRFCDAFNISIVSL 362 Query: 367 VDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADF 426 VDVPG+LPG QE GII+HGAK+LYAYAEATVP +TVI RKAYGGAY+ M SKHL D Sbjct: 363 VDVPGFLPGTSQEHEGIIKHGAKLLYAYAEATVPKITVITRKAYGGAYIVMNSKHLRGDI 422 Query: 427 VFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYID 486 +AW +EIAVMG EGAA IIF++E E +KQKI EYR+ +P+VAASRGY+D Sbjct: 423 NYAWFNSEIAVMGAEGAAEIIFKEEC----KDNEAKKQKIDEYRKVVTSPFVAASRGYLD 478 Query: 487 DVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 D+I P TR +I AL L K+V LP KKH N+PL Sbjct: 479 DIIRPQNTRWRICKALNFLRTKKVSLPWKKHDNLPL 514 >sp|P53003|PCCB_SACER PROPIONYL-COA CARBOXYLASE BETA CHAIN (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) >gi|2127500|pir||S71008 propionyl-CoA carboxylase beta chain homolog - Saccharopolyspora erythraea >gi|1177652|emb|CAA63310.1| (X92557) propionyl-CoA carboxylase [Saccharopolyspora erythraea] Length = 546 Score = 596 bits (1520), Expect = e-169 Identities = 305/530 (57%), Positives = 379/530 (70%), Gaps = 20/530 (3%) Query: 6 KVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFG 65 K+ DLY+R + + G E A+ KQH KGK TARERI++LLD GSFVE+ +HR+T FG Sbjct: 24 KLADLYRRNHEAVHAGSERAVAKQHAKGKRTARERIDMLLDEGSFVELDEHARHRSTNFG 83 Query: 66 MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125 MD DGV+TG+GT++GR V V++QDFTV GGSLGE+ KI ++M+LA++ G P++ Sbjct: 84 MDADRPYGDGVVTGWGTVDGRRVCVFSQDFTVFGGSLGEVFGEKIVKVMDLAMKTGCPLV 143 Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185 G+NDSGGARIQEGV +L Y EIFK NT SGV+PQI+ IMGPCAGGAVYSPAI DF +M Sbjct: 144 GINDSGGARIQEGVAALGLYAEIFKRNTHASGVIPQISLIMGPCAGGAVYSPAITDFTVM 203 Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245 VD S MFITGP V+K VTG DV+ LGGA H ++SG AH + +++ I +K LL Sbjct: 204 VDQTS-HMFITGPDVIKTVTGEDVSFEDLGGARTHNERSGNAHYLATDEDDAISYVKELL 262 Query: 246 SYLPSNNMEKPPRVKPKDEPFRRTP---------ELYDIVPDDPNKAYDVRQVIYAIVDR 296 S+LPSNN+ P V P E + EL +VPD PN+ YD+R+VI +VD Sbjct: 263 SFLPSNNLSSSP-VFPGAEVEEGSVADGVGDADLELDALVPDSPNQPYDMREVITRLVDE 321 Query: 297 DENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFC 356 E FLE+ FAPN + GFGRI G +VG+VAN P+ LAG LDID+S+K ARFVRFC Sbjct: 322 GE-----FLEVSALFAPNMLCGFGRIEGASVGVVANQPMQLAGTLDIDASEKAARFVRFC 376 Query: 357 DAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLA 416 DAFNIP++T VDVPG+LPG Q+ IIR GAK+LYAYAEATVP+VTVI RKAYGGAY Sbjct: 377 DAFNIPVLTLVDVPGFLPGTGQDWNAIIRRGAKLLYAYAEATVPLVTVITRKAYGGAYDV 436 Query: 417 MGSKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKA----ENPEEFRKQKIQEYREK 472 MGSKHLGAD AWPTA+IAVMG +GAANI++R+++A+A E+ E R + QEY + Sbjct: 437 MGSKHLGADINLAWPTAQIAVMGAQGAANILYRRQLAEAAERGEDVEALRARLQQEYEDT 496 Query: 473 FANPYVAASRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 NPYVAA RGY+D VI P+ TR + AL L +KR LP KKHGNIPL Sbjct: 497 LCNPYVAAERGYVDSVIPPSHTRGHVARALRMLADKREALPAKKHGNIPL 546 >pir||T42208 propionyl-CoA carboxylase complex B chain - Streptomyces coelicolor >gi|4704652|gb|AAD28194.1|AF113605_1 (AF113605) propionyl-CoA carboxylase complex B subunit [Streptomyces coelicolor A3(2)] Length = 530 Score = 596 bits (1520), Expect = e-169 Identities = 301/521 (57%), Positives = 378/521 (71%), Gaps = 11/521 (2%) Query: 6 KVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFG 65 K+ DL +R ++ G A++KQH KGKLTARERI+LLLD GSFVE+ F +HR+T FG Sbjct: 17 KLADLRRRIEEATHAGSARAVEKQHAKGKLTARERIDLLLDEGSFVELDEFARHRSTNFG 76 Query: 66 MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125 +D DGV+TGYGT++GR V V++QDFTV GG+LGE++ KI ++M+ AL+ G PV+ Sbjct: 77 LDANRPYGDGVVTGYGTVDGRPVAVFSQDFTVFGGALGEVYGQKIVKVMDFALKTGCPVV 136 Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185 G+NDSGGARIQEGV SL YGEIF+ NT SGV+PQI+ ++GPCAGGAVYSPAI DF +M Sbjct: 137 GINDSGGARIQEGVASLGAYGEIFRRNTHASGVIPQISLVVGPCAGGAVYSPAITDFTVM 196 Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245 VD S MFITGP V+K VTG DV +LGGA H SG AH + +++ + +K+LL Sbjct: 197 VDQTS-HMFITGPDVIKTVTGEDVGFEELGGARTHNSTSGVAHHMAGDEKDAVEYVKQLL 255 Query: 246 SYLPSNNMEKPPRVKPKDEPFRRT---PELYDIVPDDPNKAYDVRQVIYAIVDRDENGNP 302 SYLPSNN+ +PP P++ T EL IVPD N+ YD+ VI ++D + Sbjct: 256 SYLPSNNLSEPPAF-PEEADLAVTDEDAELDTIVPDSANQPYDMHSVIEHVLD-----DA 309 Query: 303 DFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIP 362 +F E QP FAPN + GFGR+ G+ VGIVAN P+ AG LDI +S+K ARFVR CDAFN+P Sbjct: 310 EFFETQPLFAPNILTGFGRVEGRPVGIVANQPMQFAGCLDITASEKAARFVRTCDAFNVP 369 Query: 363 IVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHL 422 ++TFVDVPG+LPGVDQE GIIR GAK+++AYAEATVP++TVI RKA+GGAY MGSKHL Sbjct: 370 VLTFVDVPGFLPGVDQEHDGIIRRGAKLIFAYAEATVPLITVITRKAFGGAYDVMGSKHL 429 Query: 423 GADFVFAWPTAEIAVMGPEGAANIIFRKEIAKA-ENPEEFRKQKIQEYREKFANPYVAAS 481 GAD AWPTA+IAVMG +GA NI+ R+ IA A ++ E R + IQEY + NPY AA Sbjct: 430 GADLNLAWPTAQIAVMGAQGAVNILHRRTIADAGDDAEATRARLIQEYEDALLNPYTAAE 489 Query: 482 RGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 RGY+D VI P++TR IV L L KR LPPKKHGNIPL Sbjct: 490 RGYVDAVIMPSDTRRHIVRGLRQLRTKRESLPPKKHGNIPL 530 >pir||T29065 probable methylmalonyl-CoA decarboxylase (EC 4.1.1.41) - Streptomyces coelicolor >gi|3355683|emb|CAA19983.1| (AL031124) putative carboxyl transferase [Streptomyces coelicolor A3(2)] Length = 527 Score = 583 bits (1486), Expect = e-165 Identities = 290/516 (56%), Positives = 369/516 (71%), Gaps = 6/516 (1%) Query: 6 KVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFG 65 +V +L+ R L E+A QH KGKLTARERIELLLDPGSF E+ +HRAT FG Sbjct: 17 RVAELHGIRAAALAGPSEKATAAQHAKGKLTARERIELLLDPGSFREVEQLRRHRATGFG 76 Query: 66 MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125 ++ + DGVITG+GT+ GR VFVYA DF + GG+LGE HA KI +IM++A+ AGAP++ Sbjct: 77 LEAKKPYTDGVITGWGTVEGRTVFVYAHDFRIFGGALGEAHATKIHKIMDMAIAAGAPLV 136 Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185 LND GARIQEGV +L GYG IF+ NT SGV+PQI+ ++GPCAGGA YSPA+ DF+ M Sbjct: 137 SLNDGAGARIQEGVSALAGYGGIFQRNTKASGVIPQISVMLGPCAGGAAYSPALTDFVFM 196 Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245 V + S MFITGP VVKAVTG ++T LGGA VHA+ SG H +E + ++ LL Sbjct: 197 VRDTSQ-MFITGPDVVKAVTGEEITQNGLGGADVHAETSGVCHFAYDDEETCLAEVRYLL 255 Query: 246 SYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFL 305 S LP NN E PPR + D RR+ L D+VP D N+ YD+ +VI +VD E +L Sbjct: 256 SLLPQNNRENPPRAESSDPVDRRSDTLLDLVPADGNRPYDMTKVIEELVDEGE-----YL 310 Query: 306 ELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVT 365 E+ +A N + R++G+ VGIVAN P LAGVLDI++S+K ARFV+ CDAFNIPI+T Sbjct: 311 EVHERWARNIICALARLDGRVVGIVANQPQALAGVLDIEASEKAARFVQMCDAFNIPIIT 370 Query: 366 FVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGAD 425 +DVPG+LPGVDQE GIIRHGAK+LYAY ATVP +++ILRKAYGGAY+ M S+ +GAD Sbjct: 371 LLDVPGFLPGVDQEHGGIIRHGAKLLYAYCNATVPRISLILRKAYGGAYIVMDSQSIGAD 430 Query: 426 FVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYI 485 +AWPT EIAVMG EGAAN+IFR++IA AE+PE R + ++EY+ + +PY AA RG + Sbjct: 431 LTYAWPTNEIAVMGAEGAANVIFRRQIADAEDPEAMRARMVKEYKSELMHPYYAAERGLV 490 Query: 486 DDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIP 521 DDVIDPAETR ++ +L L K LP +KHGN P Sbjct: 491 DDVIDPAETREVLITSLAMLHTKHADLPSRKHGNPP 526 >sp|P79384|PCCB_PIG PROPIONYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL PRECURSOR (PCCASE BETA SUBUNIT) (PROPANOYL-COA:CARBON DIOXIDE LIGASE BETA SUBUNIT) >gi|1840397|dbj|BAA19203.1| (AB000886) Propionyl-CoA carboxylase beta chain precursor [Sus scrofa] Length = 539 Score = 562 bits (1433), Expect = e-159 Identities = 293/517 (56%), Positives = 362/517 (69%), Gaps = 16/517 (3%) Query: 8 EDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGM- 66 E + +R+ L GG+ I QH +GKLTARERI LLLDPGSF+E MFV+HR +FGM Sbjct: 37 ERIENKRQAALLGGGQRRIDSQHKRGKLTARERISLLLDPGSFIESDMFVEHRCADFGMA 96 Query: 67 -DKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125 DK P D V+TG G INGRLV+V++QDFTV GGSL HA KI +IM+ A+ GAPVI Sbjct: 97 ADKNKFPGDSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAMTVGAPVI 156 Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185 GLNDSGGARIQEGV+SL GY +IF N SGV+PQI+ IMGPCAGGAVYSPA+ DF M Sbjct: 157 GLNDSGGARIQEGVESLAGYADIFLRNVSASGVIPQISLIMGPCAGGAVYSPALTDFTFM 216 Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245 V + S ++FITGP VVK+VT DVT +LGGA H SG AH +D + + ++ Sbjct: 217 VKDTS-YLFITGPDVVKSVTNEDVTQEELGGARTHTTMSGVAHRAFDNDVDALCNLREFF 275 Query: 246 SYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFL 305 +YLP +N + P + D R PEL +VP + +AYD+ +IY+IVD DF Sbjct: 276 NYLPLSNQDPAPIRECHDPSDRLVPELDTVVPLESTRAYDMVDIIYSIVDER-----DFF 330 Query: 306 ELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVT 365 E+ P +A N ++GF R+NG+TVGIV N P +G LDI+SS K ARFVRFCDAFNIP++T Sbjct: 331 EIMPNYAKNIIVGFARMNGRTVGIVGNQPKVASGCLDINSSVKGARFVRFCDAFNIPLIT 390 Query: 366 FVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGAD 425 FVDVPG+LPG QE GIIRHGAK+LYA+AEATVP +TVI RKAYGGAY M SKHL D Sbjct: 391 FVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKITVITRKAYGGAYDVMSSKHLCGD 450 Query: 426 FVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYI 485 +AWPTAEIAVMG +GA IIF+ EN E + EY EKFANP+ AA RG++ Sbjct: 451 TNYAWPTAEIAVMGAKGAVEIIFKGH----ENVEAAQ----AEYIEKFANPFPAAVRGFV 502 Query: 486 DDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 DD+I P+ TRA+I L+ L +K+V+ P +KH NIPL Sbjct: 503 DDIIQPSSTRARICCDLDVLASKKVQRPWRKHANIPL 539 >pir||T45009 propionyl-CoA carboxylase (EC 6.4.1.3) beta chain precursor [validated] - human >gi|4127990|emb|CAA07066.1| (AJ006487) propionyl-CoA carboxylase [Homo sapiens] Length = 539 Score = 558 bits (1423), Expect = e-158 Identities = 293/517 (56%), Positives = 363/517 (69%), Gaps = 16/517 (3%) Query: 8 EDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGM- 66 E + +R+ L GG+ I QH +GKLTARERI LLLDPGSFVE MFV+HR +FGM Sbjct: 37 ERIENKRRTALLGGGQRRIDAQHKRGKLTARERISLLLDPGSFVESDMFVEHRCADFGMA 96 Query: 67 -DKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125 DK P D V+TG G INGRLV+V++QDFTV GGSL HA KI +IM+ A+ GAPVI Sbjct: 97 ADKNKFPGDSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVI 156 Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185 GLNDSGGARIQEGV+SL GY +IF N SGV+PQI+ IMGPCAGGAVYSPA+ DF M Sbjct: 157 GLNDSGGARIQEGVESLAGYADIFLRNVTASGVIPQISLIMGPCAGGAVYSPALTDFTFM 216 Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245 V + S ++FITGP VVK+VT DVT +LGGA H SG AH ++D + + ++ Sbjct: 217 VKDTS-YLFITGPDVVKSVTNEDVTQEELGGAKTHTTMSGVAHRAFENDVDALCNLRDFF 275 Query: 246 SYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFL 305 +YLP ++ + P + D R PEL IVP + KAY++ +I+++VD E F Sbjct: 276 NYLPLSSQDPAPVRECHDPSDRLVPELDTIVPLESTKAYNMVDIIHSVVDERE-----FF 330 Query: 306 ELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVT 365 E+ P +A N ++GF R+NG+TVGIV N P +G LDI+SS K ARFVRFCDAFNIP++T Sbjct: 331 EIMPNYAKNIIVGFARMNGRTVGIVGNQPKVASGCLDINSSVKGARFVRFCDAFNIPLIT 390 Query: 366 FVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGAD 425 FVDVPG+LPG QE GIIRHGAK+LYA+AEATVP VTVI RKAYGGAY M SKHL D Sbjct: 391 FVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKVTVITRKAYGGAYDVMSSKHLCGD 450 Query: 426 FVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYI 485 +AWPTAEIAVMG +GA IIF+ EN E + EY EKFANP+ AA RG++ Sbjct: 451 TNYAWPTAEIAVMGAKGAVEIIFKGH----ENVEAAQ----AEYIEKFANPFPAAVRGFV 502 Query: 486 DDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 DD+I P+ TRA+I L+ L +K+V+ P +KH NIPL Sbjct: 503 DDIIQPSSTRARICCDLDVLASKKVQRPWRKHANIPL 539 >pir||T16428 propionyl-CoA carboxylase (EC 6.4.1.3) beta chain F52E4.1 [similarity] - Caenorhabditis elegans >gi|1293830|gb|AAB54030.1| (U56964) Similar to propionyl-CoA carboxylase beta; coded for by C. elegans cDNA yk74f9.5; coded for by C. elegans cDNA yk51d4.5; coded for by C. elegans cDNA yk90b1.5; coded for by C. elegans cDNA yk104d12.5; coded for by C. elegans cDNA yk82f4.5; cod> Length = 536 Score = 557 bits (1420), Expect = e-157 Identities = 287/511 (56%), Positives = 360/511 (70%), Gaps = 13/511 (2%) Query: 12 QRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGMDKRDL 71 + R+K L GG++ + QH +GKLTARERI+LLLD +F E MF +H +FGM K Sbjct: 39 ETREKALLGGGKKRVDAQHARGKLTARERIDLLLDRNTFREYDMFAEHTCNDFGMQKEKY 98 Query: 72 PADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSG 131 P D V+TG G INGR VFV++QDFTV GGSL +HA KI +IM A+ GAPVIGLNDSG Sbjct: 99 PGDSVVTGRGEINGRTVFVFSQDFTVFGGSLSSIHAKKIVKIMREAMLVGAPVIGLNDSG 158 Query: 132 GARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVDNPST 191 GARIQEGV+SL GY +IF+ N + SGVVPQI+ IMGPCAGGAVYSPA+ DF MV + S Sbjct: 159 GARIQEGVESLAGYADIFQENVMASGVVPQISMIMGPCAGGAVYSPALTDFTFMVRDTS- 217 Query: 192 FMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSN 251 ++FITGP VVKAVT +VT +LGGA H SG AH +D + + ++ L +YLP + Sbjct: 218 YLFITGPDVVKAVTNEEVTQEELGGAKTHTVTSGVAHGAFDNDVDALMSLRELFNYLPLS 277 Query: 252 NMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYF 311 N + P +D R P L +VP + AY+++ V++A+VD DF E+ P + Sbjct: 278 NTDAAPIRAAEDPWDRAVPSLDTVVPLESTAAYNMKDVVHALVDEG-----DFFEIMPDY 332 Query: 312 APNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPG 371 A N VIGF R+NG+TVGIV NNP AG LDI+SS K ARFVRFCDAFNIPI+T VDVPG Sbjct: 333 AKNLVIGFARMNGRTVGIVGNNPKFAAGCLDINSSVKGARFVRFCDAFNIPIITLVDVPG 392 Query: 372 YLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAWP 431 +LPG QE GIIRHGAK+LYA+AEATVP +T+I RKA+GGAY M SKHL D +AWP Sbjct: 393 FLPGTAQEYGGIIRHGAKLLYAFAEATVPKITIITRKAFGGAYDVMSSKHLRGDINYAWP 452 Query: 432 TAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYIDDVIDP 491 TAE+AVMG +GA +I+FR N +E Q +EY E F+NP+ AA RG++DD+I P Sbjct: 453 TAEVAVMGAKGAVSILFR-------NDKEHAVQHEEEYTELFSNPFPAAVRGFVDDIIIP 505 Query: 492 AETRAKIVMALEALENKRVKLPPKKHGNIPL 522 +ETR K+ L LE+K++K P KKHGNIPL Sbjct: 506 SETRKKVCEDLNMLESKKLKNPWKKHGNIPL 536 >gi|4557044 propionyl Coenzyme A carboxylase, beta polypeptide [Homo sapiens] >gi|1709602|sp|P05166|PCCB_HUMAN PROPIONYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL PRECURSOR (PCCASE BETA SUBUNIT) (PROPANOYL-COA:CARBON DIOXIDE LIGASE BETA SUBUNIT) >gi|312812|emb|CAA51825.1| (X73424) propionyl-CoA carboxylase [Homo sapiens] Length = 539 Score = 555 bits (1415), Expect = e-157 Identities = 292/517 (56%), Positives = 362/517 (69%), Gaps = 16/517 (3%) Query: 8 EDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGM- 66 E + +R+ L GG+ I QH +GKLTARERI LLLDPGSFVE MFV+HR +FGM Sbjct: 37 ERIENKRRTALLGGGQRRIDAQHKRGKLTARERISLLLDPGSFVESDMFVEHRCADFGMA 96 Query: 67 -DKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125 DK P D V+TG G INGRLV+V++QDFTV GGSL HA KI +IM+ A+ GAPVI Sbjct: 97 ADKNKFPGDSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVI 156 Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185 GLNDSGGARIQEGV+SL GY +IF N SGV+PQI+ IMGPCAGGAVYSPA+ DF M Sbjct: 157 GLNDSGGARIQEGVESLAGYADIFLRNVTASGVIPQISLIMGPCAGGAVYSPALTDFTFM 216 Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245 V + S ++FITGP VVK+VT DVT +LGGA H SG AH ++D + + ++ Sbjct: 217 VKDTS-YLFITGPDVVKSVTNEDVTQEELGGAKTHTTMSGVAHRAFENDVDALCNLRDFF 275 Query: 246 SYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFL 305 +YLP ++ + + D R PEL IVP + KAY++ +I+++VD E F Sbjct: 276 NYLPLSSQDPASVRECHDPSDRLVPELDTIVPLESTKAYNMVDIIHSVVDERE-----FF 330 Query: 306 ELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVT 365 E+ P +A N ++GF R+NG+TVGIV N P +G LDI+SS K ARFVRFCDAFNIP++T Sbjct: 331 EIMPNYAKNIIVGFARMNGRTVGIVGNQPKVASGCLDINSSVKGARFVRFCDAFNIPLIT 390 Query: 366 FVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGAD 425 FVDVPG+LPG QE GIIRHGAK+LYA+AEATVP VTVI RKAYGGAY M SKHL D Sbjct: 391 FVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKVTVITRKAYGGAYDVMSSKHLCGD 450 Query: 426 FVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYI 485 +AWPTAEIAVMG +GA IIF+ EN E + EY EKFANP+ AA RG++ Sbjct: 451 TNYAWPTAEIAVMGAKGAVEIIFKGH----ENVEAAQ----AEYIEKFANPFPAAVRGFV 502 Query: 486 DDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 DD+I P+ TRA+I L+ L +K+V+ P +KH NIPL Sbjct: 503 DDIIQPSSTRARICCDLDVLASKKVQRPWRKHANIPL 539 >gb|AAD13544.1| (AF080235) decarboxylase homolog [Streptomyces cyanogenus] Length = 524 Score = 554 bits (1412), Expect = e-157 Identities = 282/519 (54%), Positives = 361/519 (69%), Gaps = 6/519 (1%) Query: 3 MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRAT 62 + +++++L + +++ + A ++QH KGKLTA ERIELLLD SF E+ +HRA Sbjct: 11 IQDRLDELRELKRQAREGLDPSATERQHAKGKLTAYERIELLLDEDSFNEVEPLRRHRAQ 70 Query: 63 EFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGA 122 FG++ + DGVITG+GT+ GR VFVYA DF + GG+LGE HA KI +IM++AL AGA Sbjct: 71 GFGLEAKKPYTDGVITGWGTVEGRTVFVYAHDFRIFGGALGEAHATKIHKIMDMALSAGA 130 Query: 123 PVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDF 182 P++ LND GARIQEGV +L GYG IF+ NT SGV+PQI+ ++GPCAGGA YSPA+ DF Sbjct: 131 PLVSLNDGAGARIQEGVTALAGYGGIFQRNTKASGVIPQISVMLGPCAGGAAYSPALTDF 190 Query: 183 ILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIK 242 + MV S MFITGP VVKAVTG ++T LGGA VHA SG AH +E + ++ Sbjct: 191 VFMVRETSQ-MFITGPDVVKAVTGEEITQNGLGGADVHAGTSGVAHFAYDDEESCLQEVR 249 Query: 243 RLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNP 302 LLS LP+NN E P D R T L +VP D ++YD+R VI IVD E+ Sbjct: 250 FLLSLLPANNRELAPVEDSGDPAERLTEALLTLVPADSGRSYDIRAVIEEIVDGGEH--- 306 Query: 303 DFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIP 362 E+ P + N V R++G VGIVAN P +AGVLDI+SS+K ARFV+FCDAFNIP Sbjct: 307 --FEVHPAWGANLVCALARLDGHVVGIVANQPTVMAGVLDIESSEKGARFVQFCDAFNIP 364 Query: 363 IVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHL 422 +VT VDVPG+LPGVDQE GIIR GAK+LYAY ATVP V+++LRKAYGGAY+ M S+ + Sbjct: 365 LVTLVDVPGFLPGVDQEHSGIIRRGAKLLYAYCNATVPRVSLVLRKAYGGAYIVMDSRSI 424 Query: 423 GADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASR 482 GAD AWPT EIAVMG EGAAN+IFR+EI +++PE R+Q+I+EYR + +PY A R Sbjct: 425 GADLALAWPTNEIAVMGAEGAANVIFRREINASDDPESVRRQRIKEYRTELMHPYYGAER 484 Query: 483 GYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIP 521 G IDDVIDP +TR ++ +L L K LP +KHGN P Sbjct: 485 GLIDDVIDPRDTRRVLIRSLAMLRAKHADLPSRKHGNPP 523 >pir||A53020 propionyl-CoA carboxylase (EC 6.4.1.3) beta chain precursor - human >gi|455713|gb|AAB28900.1| (S67325) propionyl CoA carboxylase beta subunit, beta PCC {EC 6.4.1.3} [human, liver, placenta, HL 1008, Peptide, 539 aa] [Homo sapiens] Length = 539 Score = 553 bits (1409), Expect = e-156 Identities = 291/517 (56%), Positives = 361/517 (69%), Gaps = 16/517 (3%) Query: 8 EDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGM- 66 E + +R+ L GG+ I +GKLTARERI LLLDPGSFVE MFV+HR +FGM Sbjct: 37 ERIENKRRTALLGGGQRRIDAHDKRGKLTARERISLLLDPGSFVESDMFVEHRCADFGMA 96 Query: 67 -DKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125 DK P D V+TG G INGRLV+V++QDFTV GGSL HA KI +IM+ A+ GAPVI Sbjct: 97 ADKNKFPGDSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVI 156 Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185 GLNDSGGARIQEGV+SL GY +IF N SGV+PQI+ IMGPCAGGAVYSPA+ DF M Sbjct: 157 GLNDSGGARIQEGVESLAGYADIFLRNVTASGVIPQISLIMGPCAGGAVYSPALTDFTFM 216 Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245 V + S ++FITGP VVK+VT DVT +LGGA H SG AH ++D + + ++ Sbjct: 217 VKDTS-YLFITGPDVVKSVTNEDVTQEELGGAKTHTTMSGVAHRAFENDVDALCNLRDFF 275 Query: 246 SYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFL 305 +YLP ++ + P + D R PEL IVP + KAY++ +I+++VD E F Sbjct: 276 NYLPLSSQDPAPVRECHDPSDRLVPELDTIVPLESTKAYNMVDIIHSVVDERE-----FF 330 Query: 306 ELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVT 365 E+ P +A N ++GF R+NG+TVGIV N P +G LDI+SS K ARFVRFCDAFNIP++T Sbjct: 331 EIMPNYAKNIIVGFARMNGRTVGIVGNQPKVASGCLDINSSVKGARFVRFCDAFNIPLIT 390 Query: 366 FVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGAD 425 FVDVPG+LPG QE GIIRHGAK+LYA+AEATVP VTVI RKAYGGAY M SKHL D Sbjct: 391 FVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKVTVITRKAYGGAYDVMSSKHLCGD 450 Query: 426 FVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYI 485 +AWPTAEIAVMG +GA IIF+ EN E + EY EKFANP+ AA RG++ Sbjct: 451 TNYAWPTAEIAVMGAKGAVEIIFKGH----ENVEAAQ----AEYIEKFANPFPAAVRGFV 502 Query: 486 DDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 DD+I P+ TRA+I L+ L +K+V+ P +KH NIPL Sbjct: 503 DDIIQPSSTRARICCDLDVLASKKVQRPWRKHANIPL 539 >pir||A70980 probable accD5 protein - Mycobacterium tuberculosis (strain H37RV) >gi|1877335|emb|CAB07063.1| (Z92771) accD5 [Mycobacterium tuberculosis] Length = 548 Score = 552 bits (1408), Expect = e-156 Identities = 284/528 (53%), Positives = 364/528 (68%), Gaps = 18/528 (3%) Query: 6 KVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFG 65 K+ +L++RR++ L GE+A++K H KGKLTARERI LLD SFVE+ KHR+T F Sbjct: 28 KLAELHKRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDSFVELDALAKHRSTNFN 87 Query: 66 MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125 + ++ DGV+TGYGTI+GR V +++QD TV GGSLGE++ KI ++ ELA++ G P+I Sbjct: 88 LGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLI 147 Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185 G+ND GARIQEGV SL Y IF+ N + SGV+PQI+ IMG AGG VYSPA+ DF++M Sbjct: 148 GINDGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPALTDFVIM 207 Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245 VD S MFITGP V+K VTG +VT +LGGA H KSG AH +++ ++ LL Sbjct: 208 VDQTSQ-MFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQDAFDYVRELL 266 Query: 246 SYLPSNNMEKPPRVK------PKDEPFRRTP-ELYDIVPDDPNKAYDVRQVIYAIVDRDE 298 SYLP NN PR + P +E EL ++PD PN+ YD+ +VI ++D Sbjct: 267 SYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQPYDMHEVITRLLD--- 323 Query: 299 NGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDA 358 +FLE+Q +A N V+GFGRI+G+ VGIVAN P H AG LDI++S+K ARFVR CD Sbjct: 324 ---DEFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFAGCLDINASEKAARFVRTCDC 380 Query: 359 FNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMG 418 FNIPIV VDVPG+LPG DQE GIIR GAK+LYAY EATVP +TVI RKAYGGAY MG Sbjct: 381 FNIPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMG 440 Query: 419 SKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKA----ENPEEFRKQKIQEYREKFA 474 SK +G D AWPTA+IAVMG GA ++R+++A+A E+ ++ R + QEY + Sbjct: 441 SKDMGCDVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEYEDTLV 500 Query: 475 NPYVAASRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 NPYVAA RGY+D VI P+ TR I AL LE K +LPPKKHGN+PL Sbjct: 501 NPYVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPPKKHGNVPL 548 >sp|P54541|PCCB_BACSU PUTATIVE PROPIONYL-COA CARBOXYLASE BETA CHAIN (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) >gi|7438115|pir||D69963 propionyl-CoA carboxylase homolog yqjD - Bacillus subtilis >gi|1303955|dbj|BAA12610.1| (D84432) YqjD [Bacillus subtilis] >gi|2634826|emb|CAB14323.1| (Z99116) similar to propionyl-CoA carboxylase [Bacillus subtilis] Length = 506 Score = 551 bits (1404), Expect = e-156 Identities = 281/511 (54%), Positives = 366/511 (70%), Gaps = 13/511 (2%) Query: 12 QRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGMDKRDL 71 + RK+ + GG E + +Q KGKLTARERI LLD SF+E+ F++ + ++ + Sbjct: 9 RNRKQAEEGGGREKLAQQRQKGKLTARERIIFLLDQDSFIELHPFMESQVLT---REQRM 65 Query: 72 PADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSG 131 DGV+TGYGTI+GR V+V+AQDFTV GG+LGE HA KI +M+LA + AP+IGLNDSG Sbjct: 66 LGDGVVTGYGTIDGRSVYVFAQDFTVYGGALGETHARKICALMDLAAKNKAPIIGLNDSG 125 Query: 132 GARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVDNPST 191 GARIQEGV SL GYG IF N + SGV+PQI+ I+GPCAGGAVYSPA+ DFI M + Sbjct: 126 GARIQEGVLSLDGYGHIFYRNVLYSGVIPQISVILGPCAGGAVYSPALTDFIFMAEQTGR 185 Query: 192 FMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSN 251 MFITGP+V++ VTG V LGGA +H SG AH G +++EV+ +++LLSYLP N Sbjct: 186 -MFITGPKVIEKVTGEQVDAESLGGAGIHNAVSGNAHFSGHTEKEVLTGVRKLLSYLPLN 244 Query: 252 NMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYF 311 P KP+ E R P L +VP D K YDVR+VI + D F E+QP+F Sbjct: 245 GRTTEP--KPEKEASR--PLLNRLVPADTTKPYDVRKVIRELADPQS-----FFEIQPFF 295 Query: 312 APNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPG 371 A N VIGF R+ + +GIVA+ P HLAG L ID++DK ARF+RFCDAF+IP++T DVPG Sbjct: 296 AKNIVIGFARLGEKAIGIVASQPKHLAGSLTIDAADKAARFIRFCDAFDIPLLTVEDVPG 355 Query: 372 YLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAWP 431 +LPG+ QE GIIRHGAK+L+AYAEATVP VT+I+RKAYGGAY+AM SK +GAD VFAWP Sbjct: 356 FLPGIQQEHNGIIRHGAKLLFAYAEATVPKVTLIIRKAYGGAYVAMNSKAIGADLVFAWP 415 Query: 432 TAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYIDDVIDP 491 AEIAVMGPEGAA+I++ KEI + +P++ +++K EY+++ A PY AA+ G +DD+I P Sbjct: 416 NAEIAVMGPEGAASILYEKEIKASADPQKTKREKTAEYKKQNAGPYKAAACGMVDDIILP 475 Query: 492 AETRAKIVMALEALENKRVKLPPKKHGNIPL 522 E+R +++ A L +K + P KKHGNIPL Sbjct: 476 EESRGRLIQAFHMLTHKTEERPKKKHGNIPL 506 >gi|8393913 propionyl Coenzyme A carboxylase, beta polypeptide [Rattus norvegicus] >gi|129686|sp|P07633|PCCB_RAT PROPIONYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL PRECURSOR (PCCASE BETA SUBUNIT) (PROPANOYL-COA:CARBON DIOXIDE LIGASE BETA SUBUNIT) >gi|92655|pir||A25516 propionyl-CoA carboxylase (EC 6.4.1.3) beta chain precursor - rat >gi|206042|gb|AAA41818.1| (M14634) prepropionyl-CoA carboxylase (EC 6.4.1.3) [Rattus norvegicus] Length = 541 Score = 550 bits (1403), Expect = e-155 Identities = 288/519 (55%), Positives = 362/519 (69%), Gaps = 20/519 (3%) Query: 8 EDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGM- 66 E + +R L GG+ I QH +GKLTARERI LLLDPGSF+E MFV+HR +FGM Sbjct: 39 ERIENKRHAALLGGGQRRIDAQHKRGKLTARERISLLLDPGSFLESDMFVEHRCADFGMA 98 Query: 67 -DKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125 +K P D V+TG G INGRLV+V++QDFTV GGSL HA KI +IM+ A+ GAPVI Sbjct: 99 AEKNKFPGDSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVI 158 Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185 GLNDSGGARIQEGV+SL GY +IF N SGV+PQI+ IMGPCAGGAVYSPA+ DF M Sbjct: 159 GLNDSGGARIQEGVESLAGYADIFLRNVTASGVIPQISLIMGPCAGGAVYSPALTDFTFM 218 Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245 V + S ++FITGP+ VK+VT DVT QLGGA H SG AH +D + + ++ L Sbjct: 219 VKDTS-YLFITGPEFVKSVTNEDVTQEQLGGAKTHTTVSGVAHRAFDNDVDALCNLREFL 277 Query: 246 SYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFL 305 ++LP +N + + D R PEL +VP + +KAY++ +I+A++D E F Sbjct: 278 NFLPLSNQDPASIRECHDPSDRLVPELDTVVPLESSKAYNMLDIIHAVIDERE-----FF 332 Query: 306 ELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVT 365 E+ P +A N VIGF R+NG+TVGIV N P +G LDI+SS K ARFVRFCDAF+IP++T Sbjct: 333 EIMPNYAKNIVIGFARMNGRTVGIVGNQPNVASGCLDINSSVKGARFVRFCDAFSIPLIT 392 Query: 366 FVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGAD 425 FVDVPG+LPG QE GIIRHGAK+LYA+AEATVP +TVI RKAYGGAY M SKHL D Sbjct: 393 FVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKITVITRKAYGGAYDVMSSKHLLGD 452 Query: 426 FVFAWPTAEIAVMGPEGAANIIFR--KEIAKAENPEEFRKQKIQEYREKFANPYVAASRG 483 +AWPTAEIAVMG +GA IIF+ +++ A+ EY EKFANP+ AA RG Sbjct: 453 TNYAWPTAEIAVMGAKGAVEIIFKGHEDVEAAQ----------AEYVEKFANPFPAAVRG 502 Query: 484 YIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 ++DD+I P+ TRA+I LE L +K+V P +KH N+PL Sbjct: 503 FVDDIIQPSSTRARICCDLEVLASKKVHRPWRKHANVPL 541 >sp|P53002|PCCB_MYCLE PROBABLE PROPIONYL-COA CARBOXYLASE BETA CHAIN (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) >gi|466841|gb|AAA85917.1| (U00012) pccB; B1308_C1_125 [Mycobacterium leprae] Length = 549 Score = 550 bits (1401), Expect = e-155 Identities = 283/528 (53%), Positives = 360/528 (67%), Gaps = 17/528 (3%) Query: 6 KVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFG 65 K+ +L++R ++ L G A +K H KGK TARERI LLD SFVE+ +HR+T FG Sbjct: 28 KLAELHKRTEEALHPVGAAAFEKVHAKGKFTARERIYALLDDDSFVELDALARHRSTNFG 87 Query: 66 MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125 + + DGV+TGYGTI+GR V +++QD TV GGSLGE++ KI ++ ELA++ G P+I Sbjct: 88 LGENRPVGDGVVTGYGTIDGRDVCIFSQDVTVFGGSLGEVYGEKIVKVQELAIKTGRPLI 147 Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185 G+ND GARIQEGV SL Y IF+ N + SGV+PQI+ IMG AGG VYSPA+ DF++M Sbjct: 148 GINDGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPALTDFVVM 207 Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245 VD S MFITGP V+K VTG DVT +LGGA H KSG AH + +++ ++ +L Sbjct: 208 VDQTSQ-MFITGPDVIKTVTGEDVTMEELGGAHTHMAKSGTAHYVASGEQDAFDWVRDVL 266 Query: 246 SYLPSNNMEKPPRV-KP------KDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDE 298 SYLPSNN PR KP +D + EL ++PD PN+ YD+ +V+ ++D +E Sbjct: 267 SYLPSNNFTDAPRYSKPVPHGSIEDNLTAKDLELDTLIPDSPNQPYDMHEVVTRLLDEEE 326 Query: 299 NGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDA 358 FLE+Q +A N V+G GRI+ + VGIVAN PI AG LDI++S+K ARFVR CD Sbjct: 327 -----FLEVQAGYATNIVVGLGRIDDRPVGIVANQPIQFAGCLDINASEKAARFVRVCDC 381 Query: 359 FNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMG 418 FNIPIV VDVPG+LPG +QE GIIR GAK+L+AY EATVP +TVI RKAYGGAY MG Sbjct: 382 FNIPIVMLVDVPGFLPGTEQEYDGIIRRGAKLLFAYGEATVPKITVITRKAYGGAYCVMG 441 Query: 419 SKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKA----ENPEEFRKQKIQEYREKFA 474 SK++G D AWPTA+IAVMG GA ++RKE+A+A N +E R Q QEY + Sbjct: 442 SKNMGCDVNLAWPTAQIAVMGASGAVGFVYRKELAQAAKNGANVDELRLQLQQEYEDTLV 501 Query: 475 NPYVAASRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 NPY+AA RGY+D VI P+ TR I AL LE K LPPKKHGNIPL Sbjct: 502 NPYIAAERGYVDAVIPPSHTRGYIATALHLLERKIAHLPPKKHGNIPL 549 >dbj|BAA33850.1| (AB018531) dtsR2 [Corynebacterium glutamicum] Length = 537 Score = 538 bits (1371), Expect = e-152 Identities = 282/528 (53%), Positives = 355/528 (66%), Gaps = 17/528 (3%) Query: 6 KVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFG 65 K+ DL R + GE ++K H G+ TARERIE LLD GSFVEI +HR+ FG Sbjct: 16 KLSDLRSRLAEAQAPMGEATVEKVHAAGRKTARERIEYLLDEGSFVEIDALARHRSKNFG 75 Query: 66 MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125 +D + DGV+TGYGTI+GR V V++QD V GG+LGE++ KI ++M+LA++ G P+I Sbjct: 76 LDAKRPATDGVVTGYGTIDGRKVCVFSQDGAVFGGALGEVYGEKIVKVMDLAIKTGVPLI 135 Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185 G+N+ GARIQEGV SL Y +IF NT SGV+PQI+ IMG CAGG VYSPA+ DFI+M Sbjct: 136 GINEGAGARIQEGVVSLGLYSQIFYRNTQASGVIPQISLIMGACAGGHVYSPALTDFIVM 195 Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245 VD S MFITGP V+K VTG DVT +LGGA H SG +H D + + ++ L Sbjct: 196 VDQTSK-MFITGPDVIKTVTGEDVTQEELGGAHTHMATSGTSHYSASDDSDALDWVRELT 254 Query: 246 SYLPSNNMEKPPRVKPK------DEPFRRTP-ELYDIVPDDPNKAYDVRQVIYAIVDRDE 298 SYLPSNN + PR + E EL I+PD PN+ YD+++VI IVD Sbjct: 255 SYLPSNNRAETPRQEADIMIGSIQENINDVDLELDTIIPDSPNQPYDMKEVISRIVD--- 311 Query: 299 NGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDA 358 + +F E+Q +A N + GF R+ G++VGIVAN P AG LDI +S+K ARF+R CDA Sbjct: 312 --DAEFFEIQEDYAENILCGFARVEGRSVGIVANQPTQFAGCLDIKASEKAARFIRTCDA 369 Query: 359 FNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMG 418 FNIPI+ FVDVPG+LPG +QE GIIR GAK+LYAYAEATV +TVI RK+YGGAY MG Sbjct: 370 FNIPILEFVDVPGFLPGTNQEFDGIIRRGAKLLYAYAEATVGKITVITRKSYGGAYCVMG 429 Query: 419 SKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKA----ENPEEFRKQKIQEYREKFA 474 SK +GAD VFAWPTA+IAVMG GA I+RKE+ +A ++ E K QEY E Sbjct: 430 SKDMGADLVFAWPTAQIAVMGASGAVGFIYRKELKQAATEGKDVAEVMKGYEQEYEETLV 489 Query: 475 NPYVAASRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 NPYVAA RG +D VI P+ETR +I+ L L+ K V +P KKHGNIPL Sbjct: 490 NPYVAAERGLVDAVIPPSETRGQIIEGLRLLDRKVVNVPAKKHGNIPL 537 >pir||JC4991 detergent sensitivity rescuer - Corynebacterium glutamicum >gi|3767579|dbj|BAA33848.1| (AB018530) dtsR [Corynebacterium glutamicum] >gi|3767581|dbj|BAA33849.1| (AB018531) dtsR1 [Corynebacterium glutamicum] Length = 543 Score = 501 bits (1276), Expect = e-141 Identities = 267/529 (50%), Positives = 342/529 (64%), Gaps = 19/529 (3%) Query: 6 KVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFG 65 K+ DL RR + GE+A++K H G+LTARER++ LLD GSF+E +HR T FG Sbjct: 22 KIADLKARRAEAHFPMGEKAVEKVHAAGRLTARERLDYLLDEGSFIETDQLARHRTTAFG 81 Query: 66 MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125 + + DG++TG+GTI+GR V +++QD TV GG+LGE++ K+ +IMELA++ G P+I Sbjct: 82 LGAKRPATDGIVTGWGTIDGREVCIFSQDGTVFGGALGEVYGEKMIKIMELAIDTGRPLI 141 Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185 GL + GARIQ+G SL + F N SGV+PQI+ IMG CAGG Y PA+ DF++M Sbjct: 142 GLYEGAGARIQDGAVSLDFISQTFYQNIQASGVIPQISVIMGACAGGNAYGPALTDFVVM 201 Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245 VD S MF+TGP V+K VTG ++T +LGGA H +G +H +DEE + ++ L+ Sbjct: 202 VDKTSK-MFVTGPDVIKTVTGEEITQEELGGATTHMVTAGNSHYTAATDEEALDWVQDLV 260 Query: 246 SYLPSNNMEKPPRVKPKDEPFRRTPE--------LYDIVPDDPNKAYDVRQVIYAIVDRD 297 S+LPSNN P ++ DE E L +I+PD YDVR VI + D Sbjct: 261 SFLPSNNRSYTP-LEDFDEEEGGVEENITADDLKLDEIIPDSATVPYDVRDVIECLTDDG 319 Query: 298 ENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCD 357 E +LE+Q A N VI FGRI GQ+VG VAN P AG LDIDSS+K ARFVR CD Sbjct: 320 E-----YLEIQADRAENVVIAFGRIEGQSVGFVANQPTQFAGCLDIDSSEKAARFVRTCD 374 Query: 358 AFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAM 417 AFNIPIV VDVPG+LPG QE GI+R GAK+LYAY EATVP +TV +RKAYGGAY M Sbjct: 375 AFNIPIVMLVDVPGFLPGAGQEYGGILRRGAKLLYAYGEATVPKITVTMRKAYGGAYCVM 434 Query: 418 GSKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEI----AKAENPEEFRKQKIQEYREKF 473 GSK LG+D AWPTA+IAVMG GA I+RKE+ AK + K +EY + Sbjct: 435 GSKGLGSDINLAWPTAQIAVMGAAGAVGFIYRKELMAADAKGLDTVALAKSFEREYEDHM 494 Query: 474 ANPYVAASRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 NPY AA RG ID VI P+ETR +I L L++K V P +KHGN+PL Sbjct: 495 LNPYHAAERGLIDAVILPSETRGQISRNLRLLKHKNVTRPARKHGNMPL 543 >pir||A48665 methylmalonyl-CoA carboxyltransferase (EC 2.1.3.1) 12S chain - Propionibacterium freudenreichii subsp. shermanii >gi|150933|gb|AAA25676.1| (L04196) methylmalonyl-CoA carboxyltransferase subunit 12S monomer [Propionibacterium freudenreichii subsp. shermanii] Length = 605 Score = 450 bits (1146), Expect = e-125 Identities = 265/520 (50%), Positives = 331/520 (62%), Gaps = 14/520 (2%) Query: 3 MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRAT 62 M +VE L ++R+ I GGE ++KQH +GK TARER+ LLDP SF E+G F KHR T Sbjct: 13 MEGRVEQLAEQRQVIEAGGGERLVEKQHSQGKQTARERLNNLLDPHSFDEVGAFRKHRTT 72 Query: 63 EFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGA 122 FGMDK +PADGV+TG GTI GR V +QDFTVMGGS + +R AL G Sbjct: 73 LFGMDKAVVPADGVVTGRGTILGRPVHAASQDFTVMGGSAWRDAVHEGRRDDGTALLTGT 132 Query: 123 PVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDF 182 P + DSGG RIQEG+DSL GYG++F N LSGVVPQI I GPCA A YSPA+ DF Sbjct: 133 PFLFFYDSGG-RIQEGIDSLSGYGKMFFANVKLSGVVPQIAIIAGPCA-CASYSPALTDF 190 Query: 183 ILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIK 242 I+M MFITGPQV+K+VTG DVT +LGGA S + + + D+ + K Sbjct: 191 IIM--TKKAHMFITGPQVIKSVTGEDVTADELGGA-EPIWPSRAIYFVAEDDDAAELIAK 247 Query: 243 RLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNP 302 +LLS+LP NN E+ V P ++ T EL DIVP D K YDVR VI IVD Sbjct: 248 KLLSFLPQNNTEEASFVNPNNDVSPNT-ELRDIVPIDGKKGYDVRDVIAKIVDWG----- 301 Query: 303 DFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIP 362 D+LE++ +A N V F R+NG++VGIVAN P ++G LDI++SDK A FV FCD+FNIP Sbjct: 302 DYLEVKAGYATNLVTAFARVNGRSVGIVANQPSVMSGCLDINASDKAAEFVNFCDSFNIP 361 Query: 363 IVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHL 422 +V VDVPG+LP V QE GIIRHG K+LYAY+EATVP +T + + + L Sbjct: 362 LVQLVDVPGFLP-VQQEYGGIIRHGRKMLYAYSEATVPKITCLATPTAAPTW-PCATVTL 419 Query: 423 GADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASR 482 P+AEIAVMG EGAAN+IFRKEI A++P+ R +KI+EY + + +R Sbjct: 420 VPTPCTPVPSAEIAVMGAEGAANVIFRKEIKAADDPDAMRAEKIEEY-QNGSTRRTWRAR 478 Query: 483 GYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 G +DDVIDPA+TR KI ALE KR P KK +PL Sbjct: 479 GQVDDVIDPADTRRKIASALEMYATKRQTRPAKKPWKLPL 518 >pir||C70887 probable Propionyl-CoA carboxylase - Mycobacterium tuberculosis (strain H37RV) >gi|2950418|emb|CAA17863.1| (AL022076) accD4 [Mycobacterium tuberculosis] Length = 518 Score = 439 bits (1118), Expect = e-122 Identities = 234/509 (45%), Positives = 325/509 (62%), Gaps = 15/509 (2%) Query: 5 EKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEF 64 EK+ +L +R + + GGE+A K+ KG +AR RI L+DPGSF+EIG + Sbjct: 13 EKLAELRERLELAKEPGGEKAAAKRDKKGIPSARARIYELVDPGSFMEIGALCRTPG--- 69 Query: 65 GMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPV 124 D L DGV+TG+G INGR V V++ D TV GG++GEM K+ R+ME G P+ Sbjct: 70 --DPNALYGDGVVTGHGLINGRPVGVFSHDQTVFGGTVGEMFGRKVARLMEWCAMVGCPI 127 Query: 125 IGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFIL 184 +G+NDSGGARIQ+ V SL Y E+ + + +LSG+VPQI+ I+G CAGGAVYSP D ++ Sbjct: 128 VGINDSGGARIQDAVTSLAWYAELGRRHELLSGLVPQISIILGKCAGGAVYSPIQTDLVV 187 Query: 185 MVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRL 244 V + +MF+TGP V+K VTG DV+ +LGGA H G H + +S+ ++ Sbjct: 188 AVRDQG-YMFVTGPDVIKDVTGEDVSLDELGGA-DHQASYGNIHQVVESEAAAYQYVRDF 245 Query: 245 LSYLPSNNMEKPPRVKPKDEP--FRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNP 302 LS+LPSN +KPP V P EP EL IVPD N AYD+ +V+ I D + Sbjct: 246 LSFLPSNCFDKPPVVNPGLEPEITGHDLELDSIVPDSDNMAYDMHEVLLRIFD-----DG 300 Query: 303 DFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIP 362 DFL++ + G+ R++G+TVG+VAN P+H++G +D ++SDK ARF+RF DAF+IP Sbjct: 301 DFLDVAAQAGQAIITGYARVDGRTVGVVANQPMHMSGAIDNEASDKAARFIRFSDAFDIP 360 Query: 363 IVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHL 422 +V VD PG+LPGV+QE GII+ G + LYA EA VP VT+ +RK+YGGAY MGSK L Sbjct: 361 LVFVVDTPGFLPGVEQEKNGIIKRGGRFLYAVVEADVPKVTITIRKSYGGAYAVMGSKQL 420 Query: 423 GADFVFAWPTAEIAVMGPEGAANIIFRK-EIAKAENPEEFRKQKIQEYREKFANPYVAAS 481 AD FAWPTA IAV+G +GAA ++ ++ A + RK ++ Y A P++AA Sbjct: 421 TADLNFAWPTARIAVIGADGAAQLLMKRFPDPNAPEAQAIRKSFVENYNLNMAIPWIAAE 480 Query: 482 RGYIDDVIDPAETRAKIVMALEALENKRV 510 RG+ID VIDP ETR + ++ L +K++ Sbjct: 481 RGFIDAVIDPHETRLLLRKSMHLLRDKQL 509 >sp|Q10506|PCCB_MYCTU PROBABLE PROPIONYL-COA CARBOXYLASE BETA CHAIN (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) >gi|7438117|pir||C70779 probable accD6 protein - Mycobacterium tuberculosis (strain H37RV) >gi|3261571|emb|CAA94668.1| (Z70692) accD6 [Mycobacterium tuberculosis] Length = 473 Score = 351 bits (891), Expect = 1e-95 Identities = 196/491 (39%), Positives = 290/491 (58%), Gaps = 23/491 (4%) Query: 35 LTARERIELLLDPGS-FVEIGMFVKHRATEFGMDKRDLPADGVITGYGTINGRLVFVYAQ 93 + A E + LDP + + F + E + +RD GV+ GT+NG + Sbjct: 3 IMAPEAVGESLDPRDPLLRLSNFFDDGSVEL-LHERD--RSGVLAAAGTVNGVRTIAFCT 59 Query: 94 DFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNT 153 D TVMGG++G I + A+E +P++G+ SGGAR+ EGV +L G++F+ Sbjct: 60 DGTVMGGAMGVEGCTHIVNAYDTAIEDQSPIVGIWHSGGARLAEGVRALHAVGQVFEAMI 119 Query: 154 ILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQ 213 SG +PQI+ ++G AGGA Y PA+ D ++M P + +F+TGP VV++VTG DV Sbjct: 120 RASGYIPQISVVVGFAAGGAAYGPALTDVVVMA--PESRVFVTGPDVVRSVTGEDVDMAS 177 Query: 214 LGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELY 273 LGG H +KSG H++ + + +RL+ + + D +++ Sbjct: 178 LGGPETHHKKSGVCHIVADDELDAYDRGRRLVGLFCQQGHFDRSKAEAGDT------DIH 231 Query: 274 DIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANN 333 ++P+ +AYDVR ++ AI+D D F E Q +AP+ V+G GR++G+TVG++ANN Sbjct: 232 ALLPESSRRAYDVRPIVTAILDADT----PFDEFQANWAPSMVVGLGRLSGRTVGVLANN 287 Query: 334 PIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYA 393 P+ L G L+ +S++K ARFVR CDAF IP+V VDVPGYLPGVDQE G++R GAK+L+A Sbjct: 288 PLRLGGCLNSESAEKAARFVRLCDAFGIPLVVVVDVPGYLPGVDQEWGGVVRRGAKLLHA 347 Query: 394 YAEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIA 453 + E TVP VT++ RK YGGAY+AM S+ L A VFAWP AE+AVMG + A I+ +K++A Sbjct: 348 FGECTVPRVTLVTRKTYGGAYIAMNSRSLNATKVFAWPDAEVAVMGAKAAVGILHKKKLA 407 Query: 454 KA-ENPEEFRKQKIQEYREKFANPYVAA-SRGYIDDVIDPAETRAKIVMALEALENKRVK 511 A E+ E ++ E+ A +A G +D+ IDPA TR+K+ AL +R Sbjct: 408 AAPEHEREALHDQLAAEHERIAGGVDSALDIGVVDEKIDPAHTRSKLTEALAQAPARR-- 465 Query: 512 LPPKKHGNIPL 522 +H NIPL Sbjct: 466 ---GRHKNIPL 473 >pir||T44709 acetyl/propionyl CoA carboxylase [imported] - Mycobacterium leprae >gi|3150227|emb|CAA19199.1| (AL023635) Acetyl/Propionyl CoA Carboxylase [Mycobacterium leprae] Length = 473 Score = 344 bits (872), Expect = 2e-93 Identities = 186/450 (41%), Positives = 268/450 (59%), Gaps = 19/450 (4%) Query: 75 GVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGAR 134 GV GT+NG + D TVMGG++G I + A+E +P++G+ SGGAR Sbjct: 41 GVFAATGTVNGLRTIAFCTDGTVMGGAMGIEGCAHIVNAYDTAIEEQSPIVGIWHSGGAR 100 Query: 135 IQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFMF 194 + EGV +L G++F+ SG +PQI+ ++G AGGA Y PA+ D ++M P +F Sbjct: 101 LAEGVRALHAVGQVFEAMIRASGYIPQISVVVGFAAGGAAYGPALTDVVIMA--PEGRVF 158 Query: 195 ITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSNNME 254 +TGP VV++VTG DV LGG H +KSG H++ + + +RL+ Sbjct: 159 VTGPDVVRSVTGEDVDMASLGGPETHHKKSGVCHIVANDELDAYERGRRLVGLFCQQGHF 218 Query: 255 KPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYFAPN 314 + + D + ++P+ +AYDV V+ AI+D N F E Q +AP+ Sbjct: 219 DRSKAEAGDT------NIQALLPESSRRAYDVHPVVTAILDE----NTPFDEFQANWAPS 268 Query: 315 AVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPGYLP 374 V+G GR++G+TVG++ANNP+ L G L+ +S++K ARFVR CDAF IP+V VDVPGYLP Sbjct: 269 MVVGLGRLSGRTVGVLANNPLRLGGCLNSESAEKAARFVRLCDAFGIPLVVIVDVPGYLP 328 Query: 375 GVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAWPTAE 434 GVDQE G++R GAK+L+A+ E TVP VT++ RK YGGAY+AM S+ L A VFAWP AE Sbjct: 329 GVDQEWGGVVRRGAKLLHAFGECTVPRVTLVTRKTYGGAYIAMNSRSLNATKVFAWPDAE 388 Query: 435 IAVMGPEGAANIIFRKEIAKAENPE-EFRKQKIQEYREKFANPYVAA-SRGYIDDVIDPA 492 +AVMG + A I+ ++++A A N E E + E+ A +A G +D+ I+PA Sbjct: 389 VAVMGAKAAVGILHKRKLAAAPNDEREALHDDLAAEHERIAGGVDSAIDIGVVDEKINPA 448 Query: 493 ETRAKIVMALEALENKRVKLPPKKHGNIPL 522 TR+K+ AL +R +H NIPL Sbjct: 449 HTRSKLTEALAQSPVRR-----GRHKNIPL 473 >pir||B69893 propionyl-CoA carboxylase homolog yngE - Bacillus subtilis >gi|2634204|emb|CAB13704.1| (Z99113) similar to propionyl-CoA carboxylase [Bacillus subtilis] Length = 595 Score = 343 bits (871), Expect = 3e-93 Identities = 205/526 (38%), Positives = 294/526 (54%), Gaps = 22/526 (4%) Query: 3 MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRAT 62 +M+ ++ +R ++I + G E+ + +KGKL RER+ LL D +E F + + Sbjct: 86 LMDYEKERTERAERIRKGGAEKYHQSNREKGKLFVRERLSLLFDDDIELEDAFFAECMSD 145 Query: 63 EFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGA 122 LPADGV+T G I G+ V V A D TV GS G KI RI E+A + Sbjct: 146 -------GLPADGVVTAIGKIGGQTVCVMANDSTVKAGSWGAKTVEKIIRIQEIAEKLNC 198 Query: 123 PVIGLNDSGGARIQEGVDSL---KGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAI 179 P+I L DS GARI + ++ +G G IF LSG +PQI + GP A G Y PA Sbjct: 199 PLIYLVDSAGARITDQINVFPGRRGAGRIFYNQVKLSGRIPQICLLFGPSAAGGAYIPAF 258 Query: 180 GDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIG 239 D ++MVD ++ M++ P++ + V G V+ ++GGA +H SG ++ +++EE I Sbjct: 259 CDIVVMVDGNAS-MYLGSPRMAEMVIGEKVSLEEMGGARMHCSISGCGDILAETEEEAIQ 317 Query: 240 LIKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDEN 299 L++ LSY P+N EK P + + TP L D++P + N +D+ ++I ++D D Sbjct: 318 LVRAYLSYFPANFQEKAPIHEKRPPKHFETP-LADVIPQNQNAPFDMHELIERVIDEDS- 375 Query: 300 GNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAF 359 F E++ FAP + G RI+GQ VGIVAN P GVL DS+DK A+F+ CDAF Sbjct: 376 ----FFEIKALFAPELLTGLARIHGQPVGIVANQPKVKGGVLFHDSADKAAKFITLCDAF 431 Query: 360 NIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGS 419 +IP++ D+PG++ G E GIIRHGAK++ A +EATVP ++VI+RKAYG AM Sbjct: 432 HIPLLFLADIPGFMIGTKVEQAGIIRHGAKMISAMSEATVPKLSVIVRKAYGAGLYAMAG 491 Query: 420 KHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKF---ANP 476 D A PTA+IAVMGPE A N ++ K+I AE PEE R I RE++ N Sbjct: 492 PAFEPDCCLALPTAQIAVMGPEAAVNAVYAKKI--AELPEEERAAFISSKREEYKEDINI 549 Query: 477 YVAASRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 Y AS ID VI R ++ L+A K + +KH P+ Sbjct: 550 YRLASEMIIDAVIPANSLRDELAKRLKAYMTKEMTFTNRKHPVYPV 595 >dbj|BAB04855.1| (AP001511) propionyl-CoA carboxylase [Bacillus halodurans] Length = 504 Score = 341 bits (866), Expect = 1e-92 Identities = 200/514 (38%), Positives = 290/514 (55%), Gaps = 22/514 (4%) Query: 15 KKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGMDKRDLPAD 74 +K+ + G E+ + KGKL AR+R+ELL D G E G+F + LPAD Sbjct: 7 EKLKRGGSEKYHEANQQKGKLFARKRLELLFDDGLAAEDGLFANCQVD-------GLPAD 59 Query: 75 GVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGAR 134 GVITG G ING+ V V A D TV GS G KI RI E A + P++ L DS GAR Sbjct: 60 GVITGIGKINGQTVCVMANDSTVKAGSWGARTVEKIIRIQETAEKLNVPMLYLVDSAGAR 119 Query: 135 IQEGVDSL---KGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVDNPST 191 I + V+ +G G IF LSG VPQ+ + GP A G Y PA D ++MVD ++ Sbjct: 120 ITDQVEMFPGRRGAGRIFYNQVKLSGRVPQVCILFGPSAAGGAYIPAFCDVVIMVDGNAS 179 Query: 192 FMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSN 251 M++ P++ + V G V+ ++GGA +H SG ++ S+EE IGL + L Y PS+ Sbjct: 180 -MYLGSPRMAEMVIGEKVSLEEMGGAKMHCSVSGCGDILAPSEEEAIGLARDYLRYFPSS 238 Query: 252 NMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYF 311 ++PP ++ EP T + +I+P + N +++ +I ++D D F E++ F Sbjct: 239 YSKRPP-IEDGREPKSFTKTIEEILPKNQNAPFNMYDLIDRVIDEDS-----FFEIKKLF 292 Query: 312 APNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPG 371 AP + G RI+G+ +GI+AN P GVL DS+DK A+F+ CDA++IP++ D+PG Sbjct: 293 APELITGLARIDGKPIGIIANQPKMKGGVLFHDSADKAAKFITLCDAYHIPLLFLADIPG 352 Query: 372 YLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAWP 431 ++ G E GIIRHGAK++ A +EATVP +++I+RKAYG AM D A+P Sbjct: 353 FMIGTKVERAGIIRHGAKMISAMSEATVPKISIIVRKAYGAGLYAMAGPAFEPDVCLAFP 412 Query: 432 TAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKF---ANPYVAASRGYIDDV 488 A+IAVMGPE A N ++ +I AE PEE R I E RE++ + Y AS ID + Sbjct: 413 NAQIAVMGPEAAVNAVYANKI--AELPEEERAAFIAEKREEYKQDIDVYRLASELVIDGI 470 Query: 489 IDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 I + R ++ L A +K + +KH P+ Sbjct: 471 IQGNQLREELKTRLTAYASKELTFTTRKHPVYPV 504 >gb|AAG19127.1| (AE005010) propionyl-CoA carboxylase homolog; YngE [Halobacterium sp. NRC-1] Length = 591 Score = 332 bits (841), Expect = 8e-90 Identities = 195/539 (36%), Positives = 292/539 (53%), Gaps = 27/539 (5%) Query: 1 MGMMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERI------------ELLLDPG 48 +G E+ E L + IL G E+ ++ ++ KL R+R+ +LL + G Sbjct: 60 LGPTEREEVLREEIADILDGGPEKYKQRLPEQDKLFVRDRLALWFGDDDDGDDDLLFEDG 119 Query: 49 SFVEI-GMFVKHRATEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHA 107 F G + D +PADG+ITG +GR + A DFTV GS+ E Sbjct: 120 RFAHFDGWHPNSPDVDEADDGTRVPADGLITGAADFDGRDLHFMANDFTVKAGSMAERGV 179 Query: 108 MKIKRIMELALEAGAPVIGLNDSGGARIQEGVD---SLKGYGEIFKMNTILSGVVPQITA 164 K R+ + AL+ G PV+ L DS G RI + + +G G+ + ++ LSG VPQI Sbjct: 180 EKFLRMQQRALKTGKPVLYLMDSSGGRIDQQSGFFANREGIGKYYFNHSRLSGRVPQICV 239 Query: 165 IMGPCAGGAVYSPAIGDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKS 224 + GPC GA Y+P DF +MV+ S M I P++V+ VTG + LGG VHA++S Sbjct: 240 LYGPCIAGAAYTPVFADFTIMVEGMSA-MAIASPRMVEMVTGEQIEMQDLGGPQVHAEQS 298 Query: 225 GQAHLIGKSDEEVIGLIKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAY 284 G A L+ + ++ L+ L+ YLP N+ EKPP +P P + + ++P+ PN+AY Sbjct: 299 GSADLVARDEDHARELVADLVQYLPDNSDEKPPS-QPAKPPAKPPKGIDGLIPEAPNRAY 357 Query: 285 DVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDID 344 D+ +I +VD+D F EL+P + + G+ RI+G+TVGIVAN P AG + D Sbjct: 358 DMHDLIGRVVDQDS-----FFELRPEYGAEILTGYARIDGRTVGIVANQPAQRAGAIFPD 412 Query: 345 SSDKIARFVRFCDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTV 404 +++K A FV DA+NIP++ D PG++PG E I+ G K++YA +EATVP +V Sbjct: 413 AAEKAAEFVWKSDAYNIPLLYLCDTPGFMPGSSVEKDAILEKGKKMIYATSEATVPKQSV 472 Query: 405 ILRKAYGGAYLAMGSKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQ 464 ++RKAYG AM + A P+ EI +MGPE A N ++ ++ ++PEE RKQ Sbjct: 473 VVRKAYGAGIYAMSGPAYDPESTIALPSGEIGIMGPEAAINAVYANKLDAIDDPEE-RKQ 531 Query: 465 KIQEYREKFANPYVA---ASRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNI 520 + QE RE + A AS ID+++ P+E R ++ E+ P KKHG I Sbjct: 532 REQELREAYREDIDAHRMASETVIDEIVPPSELRTELSNRFSFYEDVEKDRPSKKHGTI 590 >gb|AAF32341.1|AF218939_9 (AF218939) b-propionyl-CoA carboxylase [Bacillus subtilis] Length = 509 Score = 329 bits (835), Expect = 4e-89 Identities = 200/525 (38%), Positives = 289/525 (54%), Gaps = 22/525 (4%) Query: 4 MEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATE 63 M+ ++ +R ++I + G E+ + +KGKL RER+ LL D +E F + + Sbjct: 1 MDYEKERTERAERIQKGGAEKYHRSNQEKGKLFVRERLALLFDDDIELEDAFFAECMSD- 59 Query: 64 FGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAP 123 LPADGV+T G I G+ V A D TV GS G KI RI E A + P Sbjct: 60 ------GLPADGVVTAIGKIGGQTVCAMANDSTVKAGSWGAKTVEKIIRIQETAEKLNCP 113 Query: 124 VIGLNDSGGARIQEGVDSL---KGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG 180 +I L DS GARI + V+ +G G IF LSG +PQI + GP A G Y PA Sbjct: 114 LIYLVDSAGARITDQVNVFPGRRGAGRIFYNQVKLSGRIPQICLLFGPSAAGGAYIPAFC 173 Query: 181 DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL 240 D ++MVD ++ M++ P++ + V G V+ ++GGA +H SG ++ ++++E I L Sbjct: 174 DIVVMVDGNAS-MYLGSPRMAEMVIGEKVSLEEMGGARMHCSVSGCGDILAETEQEAIHL 232 Query: 241 IKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENG 300 + LSY P+N E+ P V+ K P L D++P + N +++ ++I ++D Sbjct: 233 ARSYLSYFPANYKERAP-VQEKRPPKPFEIPLSDVIPQNQNAPFNMFELIDRVIDEGS-- 289 Query: 301 NPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN 360 F E++ FAP + G RI+GQ VGI+AN P GVL DS+DK A+F+ CDAF+ Sbjct: 290 ---FFEIKALFAPEIITGLARIHGQPVGIIANQPKVKGGVLFHDSADKAAKFITLCDAFH 346 Query: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSK 420 IP++ D+PG++ G E GIIRHGAK++ A +EATVP ++VI+RKAYG AM Sbjct: 347 IPLLFLADIPGFMIGTKVEQAGIIRHGAKMISAMSEATVPKLSVIVRKAYGAGLYAMAGP 406 Query: 421 HLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKF---ANPY 477 D A PTA+IAVMGPE A N ++ K+I +E P+E R Q I RE++ N Y Sbjct: 407 AFEPDCCIALPTAQIAVMGPEAAVNAVYAKKI--SELPKEERAQFISSKREEYKEDINIY 464 Query: 478 VAASRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 AS ID VI R ++ L A K + +KH P+ Sbjct: 465 RLASEMIIDAVIPANSLRGELHKRLMAYMTKEITFTNRKHPVYPV 509 >sp|Q06101|PCCB_RHOER PROPIONYL-COA CARBOXYLASE BETA CHAIN (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) >gi|484519|pir||JQ1943 propionyl-CoA carboxylase (EC 6.4.1.3) beta chain - Rhodococcus sp >gi|152059|gb|AAB80770.1| (M95713) propionyl-CoA carboxylase beta chain [Rhodococcus erythropolis] Length = 476 Score = 327 bits (830), Expect = 2e-88 Identities = 176/420 (41%), Positives = 255/420 (59%), Gaps = 25/420 (5%) Query: 40 RIELLLDPGSFVEIGMFVKHRATEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMG 99 R+E L DPG+ V + DK GV+ G I+G Y D TVMG Sbjct: 22 RLENLFDPGTTVPL----------HARDK-----SGVLAASGNIDGVRTIAYCSDATVMG 66 Query: 100 GSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVV 159 G++G + + ++ A+E +P++GL SGGAR+ EGV++L G +F+ SG++ Sbjct: 67 GAMGVDGCKHLVKAIDTAIEEESPIVGLWHSGGARLAEGVEALHAVGLVFEAMVRASGLI 126 Query: 160 PQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALV 219 PQI+ ++G AGGA Y PA+ D ++M P +F+TGP VV++VTG V V LGG Sbjct: 127 PQISVVLGFAAGGAAYGPALTDVVIMA--PEGRVFVTGPDVVRSVTGEQVDMVSLGGPDT 184 Query: 220 HAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDD 279 H +KSG AH+ + + + +RL+S + + D R ++P Sbjct: 185 HTKKSGVAHIAAHDEADALHRARRLVSMMCEQGEFDQRAAELGDSDLRA------MMPAS 238 Query: 280 PNKAYDVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAG 339 +AYDVR +++ ++D E G F ELQ +A + V GFGR+ G+TVG++ANNP+ L G Sbjct: 239 AKRAYDVRPIVHEMLDNVE-GESSFEELQGNYARSIVTGFGRMAGRTVGVIANNPLRL-G 296 Query: 340 VLDIDSSDKIARFVRFCDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATV 399 L+ +S++K ARFVR C+AF +P+V VDVPGYLPGV E G++R GAK+L+A+AEATV Sbjct: 297 CLNSESAEKAARFVRLCNAFGVPLVVVVDVPGYLPGVSMEWEGVVRRGAKLLHAFAEATV 356 Query: 400 PMVTVILRKAYGGAYLAMGSKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPE 459 P VTV+ RK YGGAY+AM S+ LGA VFAWP +E+AVMG + A I+ ++ +A A + E Sbjct: 357 PRVTVVTRKIYGGAYIAMNSRALGATAVFAWPNSEVAVMGAKAAVGILHKRALAAAPDDE 416 >sp|P34385|YLP5_CAEEL HYPOTHETICAL 66.5 KD PROTEIN F02A9.5 IN CHROMOSOME III >gi|280542|pir||S28313 hypothetical protein F02A9.5 - Caenorhabditis elegans >gi|3875448|emb|CAA79618.1| (Z19555) predicted using Genefinder~similar to Propionyl-CoA carboxylase beta chain, contains similarity to Pfam domain: PF01039 (Carboxyl transferase domain), Score=826.9, E-value=2.4e-245, N=1~cDNA EST EMBL:M89018 comes from this gene~cDNA EST yk9b2.> Length = 608 Score = 287 bits (727), Expect = 2e-76 Identities = 188/527 (35%), Positives = 281/527 (52%), Gaps = 35/527 (6%) Query: 7 VEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRATEFG 65 VEDL + KI Q GGE+A+K +GK+ ARERI+ ++D GS F+E + Sbjct: 98 VEDLKAKISKIEQAGGEKAVKLHRSRGKMLARERIDGIVDAGSPFIEFSQLAGYEM---- 153 Query: 66 MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125 K ++P+ G++TG G ++GR+ + A D TV GG+ + K R E+A E P I Sbjct: 154 YGKEEVPSGGILTGVGIVSGRVCVIVANDATVKGGTYYPITVKKHLRAQEIARENKLPCI 213 Query: 126 GLNDSGGARIQEGVDSL---KGYGEIF-KMNTILSGVVPQITAIMGPCAGGAVYSPAIGD 181 L DSGGA + D + +G IF T+ S +PQ+ +MG C G Y PA+ D Sbjct: 214 YLVDSGGANLPRQADIFADSQHFGRIFYNQATMSSEGIPQLAVVMGSCTAGGAYVPAMSD 273 Query: 182 FILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLI 241 ++V T +F+ GP +VKA TG +++ +LGGA +H +SG +D+ + L Sbjct: 274 QAIIVKGTGT-VFLGGPPLVKAATGEEISAEELGGADLHCGESGVTDYYAHNDKHALYLA 332 Query: 242 KRLLSYLPSNNMEKPPRVKPK-DEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENG 300 + ++ LP +E+ P DEP E+Y IV + K YDVR+VI IVD Sbjct: 333 RSCIAGLPP--VEEHMTFNPNADEPLYPAEEIYGIVGSNLKKTYDVREVIARIVDGSR-- 388 Query: 301 NPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN 360 F E + + V GF I GQ VGI+ANN GVL +S+ K + F+ C Sbjct: 389 ---FHEFKERYGETLVTGFATIYGQRVGILANN-----GVLFAESAMKGSHFIELCCQRK 440 Query: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSK 420 IP++ ++ G++ G D E+ GI +HGAK++ A A A VP +TV++ +YG M + Sbjct: 441 IPLLFLQNITGFMVGRDAEAGGIAKHGAKLVTAVACAKVPKITVLVGGSYGAGNYGMCGR 500 Query: 421 HLGADFVFAWPTAEIAVMGPEGAANII--FRKEIAKAENPE-------EFRKQKIQEYRE 471 +VF WP + I+VMG E AAN++ +KE K E + E RK ++E E Sbjct: 501 GYSPRYVFMWPNSRISVMGGEQAANVLSTVQKEKKKREGADWTDQQDLELRK-PVEEKFE 559 Query: 472 KFANPYVAASRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHG 518 K +PY A++R + D VIDP +TR + +A ++ K +P K G Sbjct: 560 KEGHPYFASARLWDDGVIDPKDTRKVLGLAFQSTLQK--PIPETKFG 604 >emb|CAB87213.1| (AL163641) acetyl/propionyl CoA carboxylase, beta subunit [Streptomyces coelicolor A3(2)] Length = 538 Score = 283 bits (716), Expect = 4e-75 Identities = 184/501 (36%), Positives = 266/501 (52%), Gaps = 32/501 (6%) Query: 21 GGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRATEFGMDKRDLPADGVITG 79 GGE A + +GKL R+R++ LLDPGS F+E+ G+ PA GVI G Sbjct: 43 GGERARARHTARGKLLPRDRVDTLLDPGSPFLELAPLAAD-----GLYDGAAPAAGVIAG 97 Query: 80 YGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARI---Q 136 G ++GR + A D TV GG+ M K R E+ALE P + L DSGGA + Sbjct: 98 IGRVSGRECVIVANDATVKGGTYYPMTVKKHLRAQEVALENRLPCLYLVDSGGAFLPMQD 157 Query: 137 EGVDSLKGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFMFI 195 E + +G IF +SG +PQI A++G C G Y PA+ D ++V N T +F+ Sbjct: 158 EVFPDREHFGRIFYNQARMSGAGIPQIAAVLGSCTAGGAYVPAMSDEAVIVRNQGT-IFL 216 Query: 196 TGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSNNMEK 255 GP +VKA TG VT +LGG VH++ SG + + D + ++++++S LP Sbjct: 217 GGPPLVKAATGEVVTAEELGGGEVHSRVSGVTDHLAEDDPHALRIVRQIVSTLPERGA-L 275 Query: 256 PPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYFAPNA 315 P V+ EP +LY +VP D YDVR+VI +VD F E + + Sbjct: 276 PWGVEAAAEPKADPQDLYGVVPVDSRTPYDVREVIARVVDGSR-----FAEFKSEYGQTL 330 Query: 316 VIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPGYLPG 375 V GF RI+G VGIVANN G+L +S+ K A F+ CD IP+V ++ G++ G Sbjct: 331 VTGFARIHGHPVGIVANN-----GILFSESAQKGAHFIELCDQRGIPLVFLQNISGFMVG 385 Query: 376 VDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAWPTAEI 435 D E+ GI +HGAK++ A A VP +TV++ +YG +M + F++ WP A+I Sbjct: 386 RDYEAGGIAKHGAKMVTAVACTRVPKLTVVVGGSYGAGNYSMCGRAYSPRFLWMWPNAKI 445 Query: 436 AVMGPEGAANIIF---------RKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYID 486 +VMG E AA+++ R E AE E F K ++ E+ N Y A +R + D Sbjct: 446 SVMGGEQAASVLATVKRDQLEGRGEEWPAEEEESF-KAPVRAQYERQGNAYYATARLWDD 504 Query: 487 DVIDPAETRAKIVMALEALEN 507 VI+PA+TR + +AL A N Sbjct: 505 GVIEPADTRQVLGLALTACAN 525 >gb|AAF35258.1|AF059510_1 (AF059510) 3-methylcrotonyl-CoA carboxylase non-biotinylated subunit [Arabidopsis thaliana] >gi|7021224|gb|AAF35259.1|AF059511_1 (AF059511) 3-methylcrotonyl-CoA carboxylase nonbiotinylated subunit [Arabidopsis thaliana] Length = 587 Score = 277 bits (701), Expect = 2e-73 Identities = 182/520 (35%), Positives = 265/520 (50%), Gaps = 34/520 (6%) Query: 7 VEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRATEFG 65 + +L KK+L GGEEA+K+ + KL RERI+ LLDPGS F+E+ H E Sbjct: 72 LSELRSHIKKVLAGGGEEAVKRNRSRNKLLPRERIDRLLDPGSSFLELSQLAGHELYE-- 129 Query: 66 MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125 LP+ G+ITG G I+GR+ A D TV GG+ + K R E+A P I Sbjct: 130 ---EPLPSGGIITGIGPIHGRICMFMANDPTVKGGTYYPITIKKHLRAQEIAARCRLPCI 186 Query: 126 GLNDSGGARIQEGVDSL---KGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSPAIGD 181 L DSGGA + + + + +G +F +++S +PQI ++G C G Y PA+ D Sbjct: 187 YLVDSGGAYLPKQAEVFPDKENFGRVFYNESVMSSDGIPQIAIVLGSCTAGGAYIPAMAD 246 Query: 182 FILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLI 241 +MV T +F+ GP +VKA TG +V+ LGGA VH SG + + + + + Sbjct: 247 ESVMVKGNGT-IFLAGPPLVKAATGEEVSAEDLGGATVHCTVSGVSDYFAQDELHGLAIG 305 Query: 242 KRLLSYL---PSNNMEKPPRVKPK--DEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDR 296 + ++ L ME K EP EL I P D + +DVR +I IVD Sbjct: 306 RNIVKNLHMAAKQGMEGTFGSKNLVYKEPLYDINELRSIAPVDHKQQFDVRSIIARIVDG 365 Query: 297 DENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFC 356 E F E + + V GF RI GQTVGI+ NN G+L +S+ K A F+ C Sbjct: 366 SE-----FDEFKKQYGTTLVTGFARIYGQTVGIIGNN-----GILFNESALKGAHFIELC 415 Query: 357 DAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLA 416 IP+V ++ G++ G E+ GI + GAK++ A + A VP +T+I ++G A Sbjct: 416 SQRKIPLVFLQNITGFMVGSRAEANGIAKAGAKMVMAVSCAKVPKITIITGASFGAGNYA 475 Query: 417 MGSKHLGADFVFAWPTAEIAVMGPEGAANIIF--------RKEIAKAENPEEFRKQKIQE 468 M + DF+F WP A I +MG AA ++ R+ I E EE K+K + Sbjct: 476 MCGRAYSPDFMFIWPNARIGIMGGAQAAGVLTQIERATKKRQGIKWTEEEEEAFKKKTVD 535 Query: 469 YREKFANPYVAASRGYIDDVIDPAETRAKIVMALEALENK 508 E+ ANPY + +R + D VIDP +TR + + L A N+ Sbjct: 536 AYEREANPYYSTARLWDDGVIDPCDTRKVLGLCLSAALNR 575 >gb|AAG17227.1|AF217984_1 (AF217984) unknown [Homo sapiens] Length = 302 Score = 277 bits (701), Expect = 2e-73 Identities = 142/262 (54%), Positives = 183/262 (69%), Gaps = 6/262 (2%) Query: 114 MELALEAGAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGA 173 M+ A+ GAPVIGLNDSGGARIQEGV+SL GY +IF N SGV+PQI+ IMGPCAGGA Sbjct: 1 MDQAITVGAPVIGLNDSGGARIQEGVESLAGYADIFLRNVTASGVIPQISLIMGPCAGGA 60 Query: 174 VYSPAIGDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKS 233 VYSPA+ DF MV + S ++FITGP VVK+VT DVT +LGGA H SG AH ++ Sbjct: 61 VYSPALTDFTFMVKDTS-YLFITGPDVVKSVTNEDVTQEELGGAKTHTTMSGVAHRAFEN 119 Query: 234 DEEVIGLIKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAI 293 D + + ++ +YLP ++ + P + D R PEL IVP + KAY++ +I+++ Sbjct: 120 DVDALCNLRDFFNYLPLSSQDPAPVRECHDPSDRLVPELDTIVPLESTKAYNMVDIIHSV 179 Query: 294 VDRDENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFV 353 VD E F E+ P +A N ++GF R+NG+TVGIV N P +G LDI+SS K ARFV Sbjct: 180 VDERE-----FFEIMPNYAKNIIVGFARMNGRTVGIVGNQPKVASGCLDINSSVKGARFV 234 Query: 354 RFCDAFNIPIVTFVDVPGYLPG 375 RFCDAFNIP++TFVDVPG+LPG Sbjct: 235 RFCDAFNIPLITFVDVPGFLPG 256 >pir||F70550 probable accD1 protein - Mycobacterium tuberculosis (strain H37RV) >gi|2113935|emb|CAB08920.1| (Z95556) accD1 [Mycobacterium tuberculosis] Length = 529 Score = 276 bits (699), Expect = 4e-73 Identities = 179/498 (35%), Positives = 268/498 (52%), Gaps = 33/498 (6%) Query: 20 MGGEEAIKKQH-DKGKLTARERIELLLDPGS-FVEIGMFVKHRATEFGMDKRDLPADGVI 77 +GG E +K+H +GKL RER++ LLDPGS F+E+ GM + P G+I Sbjct: 32 LGGNERARKRHVSRGKLLPRERVDRLLDPGSPFLELAPLAAG-----GMYGDESPGAGII 86 Query: 78 TGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGA---R 134 TG G ++GR + A D TV GG+ M K R E+AL+ P I L DSGGA R Sbjct: 87 TGIGRVSGRQCVIVANDATVKGGTYYPMTVKKHLRAQEVALQNMLPCIYLVDSGGAFLPR 146 Query: 135 IQEGVDSLKGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFM 193 E + +G IF +S +PQ+ A++G C G Y PA+ D ++V T + Sbjct: 147 QDEVFPDREHFGRIFYNQATMSAKGIPQVAAVLGSCTAGGAYVPAMSDEAVIVREQGT-I 205 Query: 194 FITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL-SYLPSNN 252 F+ GP +VKA TG V+ +LGG +H++ SG + DE+ + +++ + ++ P Sbjct: 206 FLGGPPLVKAATGEIVSAEELGGGDLHSRTSGVTDHLADDDEDALRIVRAIADTFGPCEP 265 Query: 253 MEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYFA 312 + V+ EP ELYD+VP DP YDV +V+ IVD E F E + + Sbjct: 266 AQWD--VRRSVEPKYPQAELYDVVPPDPRVPYDVHEVVVRIVDGSE-----FSEFKAKYG 318 Query: 313 PNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPGY 372 V F R++G VGIVANN GVL +S+ K A F+ CD IP++ ++ G+ Sbjct: 319 KTLVTAFARVHGHPVGIVANN-----GVLFSESALKGAHFIELCDKRKIPLLFLQNIAGF 373 Query: 373 LPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAWPT 432 + G D E+ GI +HGAK++ A A A VP +TV++ +YG +M + F++ WP Sbjct: 374 MVGRDYEAGGIAKHGAKMVTAVACARVPKLTVVIGGSYGAGNYSMCGRAYSPRFLWMWPN 433 Query: 433 AEIAVMGPEGAANIIFR---KEIAKAENP-----EEFRKQKIQEYREKFANPYVAASRGY 484 A I+VMG E AA+++ ++++ A P EE K I+ E NPY + +R + Sbjct: 434 ARISVMGGEQAASVLATVRGEQLSAAGTPWSPDEEEAFKAPIRAQYEDQGNPYYSTARLW 493 Query: 485 IDDVIDPAETRAKIVMAL 502 D +IDPA+TR + +AL Sbjct: 494 DDGIIDPADTRTVVGLAL 511 >gi|11545863 non-biotin containing subunit of 3-methylcrotonyl-CoA carboxylase [Homo sapiens] >gi|10934059|dbj|BAB16880.1| (AB050049) non-biotin containing subunit of 3-methylcrotonyl-CoA carboxylase [Homo sapiens] Length = 563 Score = 270 bits (682), Expect = 4e-71 Identities = 179/526 (34%), Positives = 275/526 (52%), Gaps = 37/526 (7%) Query: 3 MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRA 61 M V L++R + I GGE+A +GKL RERI+ L+DPGS F+E+ F ++ Sbjct: 49 MKALVNQLHERVEHIKLGGGEKARALHISRGKLLPRERIDNLIDPGSPFLELSQFAGYQL 108 Query: 62 TEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAG 121 D ++P G+ITG G ++G + A D TV GG+ + K R E+A++ Sbjct: 109 ----YDNEEVPGGGIITGIGRVSGVECMIIANDATVKGGAYYPVTVKKQLRAQEIAMQNR 164 Query: 122 APVIGLNDSGGARIQEGVDSLKG---YGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSP 177 P I L DSGGA + D +G F I+S + QI +MG C G Y P Sbjct: 165 LPCIYLVDSGGAYLPRQADVFPDRDHFGRTFYNQAIMSSKNIAQIAVVMGSCTAGGAYVP 224 Query: 178 AIGDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEV 237 A+ D ++V T +F+ GP +VKA TG +V+ LGGA +H +KSG + D Sbjct: 225 AMADENIIVRKQGT-IFLAGPPLVKAATGEEVSAEDLGGADLHCRKSGVSDHWALDDHHA 283 Query: 238 IGLIKRLLSYLPSNNMEKP--PRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVD 295 + L ++++ L N +K ++P +EP ELY IV + +++DVR+VI IVD Sbjct: 284 LHLTRKVVRNL---NYQKKLDVTIEPSEEPLFPADELYGIVGANLKRSFDVREVIARIVD 340 Query: 296 RDENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRF 355 F E + ++ V GF RI G VGIV NN GVL +S+ K FV+ Sbjct: 341 GSR-----FTEFKAFYGDTLVTGFARIFGYPVGIVGNN-----GVLFSESAKKGTHFVQL 390 Query: 356 CDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYL 415 C NIP++ ++ G++ G + E+ GI + GAK++ A A A VP +T+I+ +YG Sbjct: 391 CCQRNIPLLFLQNITGFMVGREYEAEGIAKDGAKMVAAVACAQVPKITLIIGGSYGAGNY 450 Query: 416 AMGSKHLGADFVFAWPTAEIAVMGPEGAANIIFR----------KEIAKAENPEEFRKQK 465 M + F++ WP A I+VMG E AAN++ K+ + A+ E K+ Sbjct: 451 GMCGRAYSPRFLYIWPNARISVMGGEQAANVLATITKDQRAREGKQFSSAD--EAALKEP 508 Query: 466 IQEYREKFANPYVAASRGYIDDVIDPAETRAKIVMALEALENKRVK 511 I + E+ NPY +++R + D +IDPA+TR + ++ A N ++ Sbjct: 509 IIKKFEEEGNPYYSSARVWDDGIIDPADTRLVLGLSFSAALNAPIE 554 >gb|AAC38045.1| (U94697) propionyl-CoA carboxylase beta chain homolog [Caulobacter crescentus] >gi|6502513|gb|AAF14341.1|U86303_2 (U86303) propionyl-CoA carboxylase beta chain [Caulobacter crescentus] Length = 211 Score = 269 bits (681), Expect = 5e-71 Identities = 136/212 (64%), Positives = 164/212 (77%), Gaps = 4/212 (1%) Query: 311 FAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVP 370 +A N + GF R++G+TVGIVAN P LAGVLDIDSS K ARFVRFCDAFNIPIVTFVDVP Sbjct: 4 WAKNIICGFARMDGETVGIVANQPQVLAGVLDIDSSRKAARFVRFCDAFNIPIVTFVDVP 63 Query: 371 GYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAW 430 G++PG QE G+I+HGAK+L+AY EATVP +TVI RKAYGGAY M SKHL D +AW Sbjct: 64 GFMPGTKQEYGGLIKHGAKLLFAYTEATVPKITVITRKAYGGAYDVMSSKHLRGDLNYAW 123 Query: 431 PTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYIDDVID 490 PTAEIAVMG +GA IIFR+E A++PE ++ EY+++FANP+VAA RGYIDDVI Sbjct: 124 PTAEIAVMGAKGAVEIIFRQE---AKDPEALAARE-AEYKDRFANPFVAAQRGYIDDVIM 179 Query: 491 PAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 P TR +IV L++L+ K + P KKH NIPL Sbjct: 180 PHGTRRRIVRGLKSLKGKELSNPWKKHDNIPL 211 >gb|AAF57388.1| (AE003789) CG3267 gene product [Drosophila melanogaster] Length = 578 Score = 266 bits (674), Expect = 3e-70 Identities = 185/533 (34%), Positives = 268/533 (49%), Gaps = 43/533 (8%) Query: 3 MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRA 61 M V DL ++L+ GG++AI++ +GKL ARERI LLLD GS F+E+ H Sbjct: 48 MASLVGDLRNFTSQVLKGGGQKAIERHTSRGKLLARERINLLLDKGSPFLELSALAGHEL 107 Query: 62 TEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAG 121 + + + G++TG G + G V A D TV GGS + K R E+A E Sbjct: 108 ----YGEEVVNSGGIVTGVGRVCGTECLVVANDATVKGGSYYPITVKKHLRAQEIAQENR 163 Query: 122 APVIGLNDSGGARIQEGVDSLKG---YGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSP 177 P I L DSGGA + D +G IF +S +PQI +MG C G Y P Sbjct: 164 LPCIYLVDSGGANLPRQADVFPDKLHFGRIFYNQANMSAQGIPQIAVVMGSCTAGGAYVP 223 Query: 178 AIGDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEV 237 A+ D ++V T +F+ GP +VKA TG +V+ LGGA +H + SG DE Sbjct: 224 AMADESIIVKKQGT-IFLAGPPLVKAATGEEVSAEDLGGADLHCKTSGVTDHYALDDEHA 282 Query: 238 IGLIKRLLSYLPSN---------------NMEKPPRVKPKDEPFRRTPELYDIVPDDPNK 282 + L ++++S L + N + +EP ELY IV + K Sbjct: 283 LYLARQIVSNLNLSATNSYNDQLMHSSQVNFQTATPPSAVEEPRYDAEELYGIVGPNLTK 342 Query: 283 AYDVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLD 342 ++DVR+VI IVD F E + + V GF ++ G TVGIV NN GVL Sbjct: 343 SFDVREVIARIVDGSR-----FTEFKKLYGETLVCGFAKLYGHTVGIVGNN-----GVLF 392 Query: 343 IDSSDKIARFVRFCDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMV 402 +S+ K A F++ C IP+V ++ G++ G D E+ GI ++GAK++ A A A VP Sbjct: 393 SESALKGAHFIQLCAQRKIPLVFLQNITGFMVGRDAEANGIAKNGAKMVTAVACANVPKF 452 Query: 403 TVILRKAYGGAYLAMGSKHLGADFVFAWPTAEIAVMGPEGAANIIF------RKEIAKAE 456 TVI+ +YG M + F++ WP + I+VMG AAN++ RK K Sbjct: 453 TVIIGGSYGAGNYGMCGRAYSPRFLYMWPNSRISVMGGTQAANVMAQITEDQRKRAGKEF 512 Query: 457 NPEEFRKQK--IQEYREKFANPYVAASRGYIDDVIDPAETRAKIVMALEALEN 507 + EE +K K I E E +PY + +R + D +IDPA TR + ++L+A N Sbjct: 513 SEEEAQKLKAPIVEMFEAEGSPYYSTARLWDDGIIDPANTRQILGLSLKAALN 565 >pir||F75382 probable propionyl-CoA carboxylase, beta subunit - Deinococcus radiodurans (strain R1) >gi|6459304|gb|AAF11105.1|AE001998_2 (AE001998) propionyl-CoA carboxylase, beta subunit, putative [Deinococcus radiodurans] Length = 558 Score = 264 bits (667), Expect = 2e-69 Identities = 177/517 (34%), Positives = 261/517 (50%), Gaps = 46/517 (8%) Query: 21 GGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRATEFGMDKRDLPADGVITG 79 GG +A ++QHDKG+LTARER+ L+DPG+ F E+ F + E D P+ G +TG Sbjct: 38 GGAKAQQRQHDKGRLTARERVSKLIDPGTPFDELMTFAGYGMYE---DVGGCPSGGTVTG 94 Query: 80 YGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARI---Q 136 G I GR + A D TV G+ + A K+ R +ALE P L DS G + Sbjct: 95 IGQIGGRPWMIIANDATVKAGAFFPITAKKVIRAQTIALENHLPTAYLVDSAGVYLPMQD 154 Query: 137 EGVDSLKGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFMFI 195 E +G +F +N +S +PQI AIMG C G Y P + D ++M + +++ Sbjct: 155 EIFPDQDDFGRVFYLNARMSAAGIPQIAAIMGNCVAGGAYLPVMCDTLIMTEGSG--LYL 212 Query: 196 TGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLS-YLPSNNME 254 GP +VKA G V LGGA +H+ +G K D+ I ++ L Y P+ Sbjct: 213 AGPALVKAAIGQVVDSEDLGGASMHSAIAGTVDYKEKDDDAAINRLRALAELYAPAEPAP 272 Query: 255 KPPRVKP-KDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYFAP 313 R K +D P R +L ++V D K YDVR +I ++ D E F E +P + Sbjct: 273 FAKRRKETQDAPAR---DLTELVGFDSAKTYDVRDLIKSLADGGE-----FHEFKPEYGE 324 Query: 314 NAVIGFGRINGQTVGIVANNP------------------IHLAGVLDIDSSDKIARFVRF 355 V GF R G V VAN I + GV+ DS+DK ARF+ Sbjct: 325 TIVCGFARAGGYPVAFVANQRTVIKKKLKSGGEPGLRTRIEVGGVIYGDSADKAARFILD 384 Query: 356 CDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYL 415 + +P+V DV G++ G D E GIIR GAK++ A + + VP +T+I ++G Sbjct: 385 ANQAGVPLVFLSDVTGFMVGRDSEQEGIIRRGAKLVNAVSNSVVPKITIITGGSFGAGNY 444 Query: 416 AMGSKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKA-----ENPEEFRKQKIQEYR 470 AM K G F+FAWP+A+ AVM AA + ++A E +E + E + Sbjct: 445 AMNGKAYGPRFIFAWPSAKYAVMSGNAAAKTLLDIQLAALKRSGHEPDDEELTRLYDEVK 504 Query: 471 EKF---ANPYVAASRGYIDDVIDPAETRAKIVMALEA 504 K+ +P AA+R ++D++I+P +TRA+++ ALEA Sbjct: 505 SKYDTELDPRYAAARLWVDEIIEPNDTRARLIRALEA 541 >emb|CAA68941.1| (Y07660) B subunit of propionyl-CoA carboxylase [Mycobacterium tuberculosis] Length = 522 Score = 259 bits (656), Expect = 4e-68 Identities = 173/492 (35%), Positives = 258/492 (52%), Gaps = 43/492 (8%) Query: 21 GGEEAIKKQH-DKGKLTARERIELLLDPGS-FVEIGMFVKHRATEFGMDKRDLPADGVIT 78 G E A K +H +GKL RER++ LLDPGS F+E+ + R +R+ P G+IT Sbjct: 15 GNERARKXRHVSRGKLLPRERVDRLLDPGSPFLELAPLGRWRHVR----RRNSPGAGIIT 70 Query: 79 GYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGA----R 134 G G ++GR + A D TV GG+ M K R E+AL+ P I L DSGGA R Sbjct: 71 GIGRVSGRQCVIVANDATVKGGTYYPMTVKKHLRAQEVALQNMLPCIYLVDSGGAXPDPR 130 Query: 135 IQEGVDSLKGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFM 193 E + +G IF +S +PQ+ A++G C G Y PA+ D ++V T + Sbjct: 131 QDEVFPDREHFGRIFYNQATMSAKGIPQVAAVLGSCTAGGAYVPAMSDEAVIVREQGT-I 189 Query: 194 FITGPQVVKAVTGVDVTPVQ-LGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSNN 252 F+ GP +VKA ++ + LGG +H++ SG + DE+ + +++ + Sbjct: 190 FLGGPPLVKAPARXEIVSAEELGGGDLHSRTSGVTDHLADDDEDALRIVRAIADTF---- 245 Query: 253 MEKPPRVKPKD-EPFRRTP-----ELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLE 306 +P R +P PF R P ELYD+VP DP YDV +V+ IVD E F E Sbjct: 246 --RPVRTRPMGCAPFGRWPKYPQAELYDVVPPDPRVPYDVHEVVVRIVDGSE-----FSE 298 Query: 307 LQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTF 366 + + V F R++G VGIVANN GVL +S+ K A F+ CD IP++ Sbjct: 299 FKAKYGKTLVTAFARVHGHPVGIVANN-----GVLFSESALKGAHFIELCDKRKIPLLFL 353 Query: 367 VDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADF 426 ++ G++ G D E+ GI +HGAK++ A A A VP +TV++ +YG +M + F Sbjct: 354 QNIAGFMVGRDYEAGGIAKHGAKMVTAVACARVPKLTVVIGGSYGAGNYSMCGRAYSPRF 413 Query: 427 VFAWPTAEIAVMGPEGAANIIFR---KEIAKAENP-----EEFRKQKIQEYREKFANPYV 478 ++ WP A I+VMG E AA+++ ++++ A P EE K I+ E NPY Sbjct: 414 LWMWPNARISVMGGEQAASVLATVRGEQLSAAGTPWSPDEEEAFKAPIRAQYEDQGNPYY 473 Query: 479 AASRGYIDDVID 490 + +R + D +ID Sbjct: 474 STARLWDDGIID 485 >pir||C83395 probable acyl-CoA carboxyltransferase beta chain PA2014 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9948017|gb|AAG05402.1|AE004627_10 (AE004627) probable acyl-CoA carboxyltransferase beta chain [Pseudomonas aeruginosa] Length = 535 Score = 255 bits (645), Expect = 8e-67 Identities = 174/522 (33%), Positives = 264/522 (50%), Gaps = 30/522 (5%) Query: 3 MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRA 61 M+E+V L +I + GG A + +GKL RERI LLDPGS F+E+ H Sbjct: 22 MLEQVNALRTLLGRIHEGGGSAAQARHSARGKLLVRERINRLLDPGSPFLELSALAAHEV 81 Query: 62 TEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAG 121 +G ++ A G++ G G + G + D TV GG+ + K R +ALE Sbjct: 82 --YG---EEVAAAGIVAGIGRVEGVECMIVGNDATVKGGTYYPLTVKKHLRAQAIALENR 136 Query: 122 APVIGLNDSGGARI---QEGVDSLKGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSP 177 P I L DSGGA + E + +G IF +S +PQI +MG C G Y P Sbjct: 137 LPCIYLVDSGGANLPRQDEVFPDREHFGRIFFNQANMSARGIPQIAVVMGSCTAGGAYVP 196 Query: 178 AIGDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEV 237 A+ D +MV +T +F+ GP +VKA TG V+ +LGGA VH + SG A + D+ Sbjct: 197 AMSDETVMVREQAT-IFLAGPPLVKAATGEVVSAEELGGADVHCKVSGVADHYAEDDDHA 255 Query: 238 IGLIKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRD 297 + + +R ++ L + P+ P ELY ++P D + YDVR+VI +VD Sbjct: 256 LAIARRCVANLNWRKQGQLQCRAPR-APLYPAEELYGVIPADSKQPYDVREVIARLVDGS 314 Query: 298 ENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCD 357 E F E + F V GF ++G + I+ANN G+L +++ K A F+ Sbjct: 315 E-----FDEFKALFGTTLVCGFAHLHGYPIAILANN-----GILFAEAAQKGAHFIELAC 364 Query: 358 AFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAM 417 IP++ ++ G++ G E+ GI +HGAK++ A A A VP TV++ ++G M Sbjct: 365 QRGIPLLFLQNITGFMVGQKYEAGGIAKHGAKLVTAVACARVPKFTVLIGGSFGAGNYGM 424 Query: 418 GSKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAEN-------PEEFR-KQKIQEY 469 + F++ WP A I VMG E AA ++ + + +AE EE + K I E Sbjct: 425 CGRAYDPRFLWMWPNARIGVMGGEQAAGVLAQVKREQAERAGQQLGVEEEAKIKAPILEQ 484 Query: 470 REKFANPYVAASRGYIDDVIDPAETRAKIVMALEALENKRVK 511 E +PY +++R + D VIDPA+TR + +AL A N ++ Sbjct: 485 YEHQGHPYYSSARLWDDGVIDPAQTREVLALALSAALNAPIE 526 >pir||T05433 hypothetical protein F28A23.210 - Arabidopsis thaliana >gi|2911059|emb|CAA17569.1| (AL021961) putative protein [Arabidopsis thaliana] >gi|7270352|emb|CAB80120.1| (AL161584) putative protein [Arabidopsis thaliana] Length = 630 Score = 253 bits (640), Expect = 3e-66 Identities = 182/563 (32%), Positives = 265/563 (46%), Gaps = 77/563 (13%) Query: 7 VEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRATEFG 65 + +L KK+L GGEEA+K+ + KL RERI+ LLDPGS F+E+ H E Sbjct: 72 LSELRSHIKKVLAGGGEEAVKRNRSRNKLLPRERIDRLLDPGSSFLELSQLAGHELYE-- 129 Query: 66 MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125 LP+ G+ITG G I+GR+ A D TV GG+ + K R E+A P I Sbjct: 130 ---EPLPSGGIITGIGPIHGRICMFMANDPTVKGGTYYPITIKKHLRAQEIAARCRLPCI 186 Query: 126 GLNDSGGARIQEGVDSL---KGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSPAIGD 181 L DSGGA + + + + +G +F +++S +PQI ++G C G Y PA+ D Sbjct: 187 YLVDSGGAYLPKQAEVFPDKENFGRVFYNESVMSSDGIPQIAIVLGSCTAGGAYIPAMAD 246 Query: 182 FILMVDNPSTFMFITGPQVVK--------------AVTGVDVTPVQLGGALVHAQKSGQA 227 +MV T +F+ GP +VK A TG +V+ LGGA VH SG + Sbjct: 247 ESVMVKGNGT-IFLAGPPLVKFLENLTLNEKAFEQAATGEEVSAEDLGGATVHCTVSGVS 305 Query: 228 HLIGKSDEEVIGLIKRLLSYL---PSNNMEKPPRVKPK--DEPFRRTPELYDIVPDDPNK 282 + + + + + ++ L ME K EP EL I P D + Sbjct: 306 DYFAQDELHGLAIGRNIVKNLHMAAKQGMEGTFGSKNLVYKEPLYDINELRSIAPVDHKQ 365 Query: 283 AYDVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLD 342 +DVR +I IVD E F E + + V GF RI GQTVGI+ NN G+L Sbjct: 366 QFDVRSIIARIVDGSE-----FDEFKKQYGTTLVTGFARIYGQTVGIIGNN-----GILF 415 Query: 343 IDSSDKIARFVRFCDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMV 402 +S+ K A F+ C IP+V ++ G++ G E+ GI + GAK++ A + A VP + Sbjct: 416 NESALKGAHFIELCSQRKIPLVFLQNITGFMVGSRAEANGIAKAGAKMVMAVSCAKVPKI 475 Query: 403 TVILRKAYGGAYLAMGSKHLGADFVFAWPTAEIAVMG----------------------- 439 T+I ++G AM + DF+F WP A I +MG Sbjct: 476 TIITGASFGAGNYAMCGRAYSPDFMFIWPNARIGIMGGAQVNQNAPKCLNRNQTESKCVY 535 Query: 440 ------PEGAANIIF--------RKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYI 485 AA ++ R+ I E EE K+K + E+ ANPY + +R + Sbjct: 536 NLSVAEQNSAAGVLTQIERATKKRQGIKWTEEEEEAFKKKTVDAYEREANPYYSTARLWD 595 Query: 486 DDVIDPAETRAKIVMALEALENK 508 D VIDP +TR + + L A N+ Sbjct: 596 DGVIDPCDTRKVLGLCLSAALNR 618 >pir||D70719 probable propionyl-CoA carboxylase - Mycobacterium tuberculosis (strain H37RV) >gi|3261632|emb|CAB02011.1| (Z79700) accD2 [Mycobacterium tuberculosis] Length = 529 Score = 238 bits (602), Expect = 9e-62 Identities = 163/520 (31%), Positives = 264/520 (50%), Gaps = 31/520 (5%) Query: 3 MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRA 61 M K++++ K L GG + + + H +G LT RERIELL+DP S F+E+ + + Sbjct: 20 MSGKLDEINAELAKALAGGGPKYVDRHHARGNLTPRERIELLVDPDSPFLELSPLAAYGS 79 Query: 62 T-EFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA 120 + G ++TG G + G + A D TV GG+ KI R ++A E Sbjct: 80 NFQIGAS--------LVTGIGAVCGVECMIVANDPTVKGGTSNPWTLRKILRANQIAFEN 131 Query: 121 GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSPAI 179 PVI L +SGGA + + G++F+ T LS +P I + G G Y P + Sbjct: 132 RLPVISLVESGGADLPTQKEIFIPGGQMFRDLTRLSAAGIPTIALVFGNSTAGGAYVPGM 191 Query: 180 GDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIG 239 D ++M+ S +F+ GP +VK TG + LGGA +HA+ SG A + + I Sbjct: 192 SDHVVMIKERSK-VFLAGPPLVKMATGEESDDESLGGAEMHARISGLADYFALDELDAIR 250 Query: 240 LIKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDEN 299 + +R+++ L N +++ P P EP EL IVP D +D R+VI IVD E Sbjct: 251 IGRRIVARL--NWIKQGPAPAPVTEPLFDAEELIGIVPPDLRIPFDPREVIARIVDGSE- 307 Query: 300 GNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAF 359 F E +P + + V G+ R++G +GI+AN GVL + S K +F++ + Sbjct: 308 ----FDEFKPLYGSSLVTGWARLHGYPLGILAN----ARGVLFSEESQKATQFIQLANRA 359 Query: 360 NIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGS 419 + P++ + GY+ G D E G+I+HG+ ++ A + +TVP +++++ +YG + M Sbjct: 360 DTPLLFLHNTTGYMVGKDYEEGGMIKHGSMMINAVSNSTVPHISLLIGASYGAGHYGMCG 419 Query: 420 KHLGADFVFAWPTAEIAVMGP---EGAANIIFRKEI-AKAENPEE----FRKQKIQEYRE 471 + F+FAWP+A+ AVMG G +I+ R A+ + +E + ++ E Sbjct: 420 RAYDPRFLFAWPSAKSAVMGGAQLSGVLSIVARAAAEARGQQVDEAADAAMRAAVEGQIE 479 Query: 472 KFANPYVAASRGYIDDVIDPAETRAKIVMALEALENKRVK 511 + P V + Y D VIDP +TR + M L A+ N +K Sbjct: 480 AESLPLVLSGMLYDDGVIDPRDTRTVLGMCLSAIANGPIK 519 >emb|CAB95891.1| (AL359988) putative acetyl/propionyl CoA carboxylase, beta subunit [Streptomyces coelicolor A3(2)] Length = 532 Score = 238 bits (600), Expect = 2e-61 Identities = 163/513 (31%), Positives = 254/513 (48%), Gaps = 29/513 (5%) Query: 3 MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRA 61 M+ K+ DL K L GGE+ + + +GKL ARERIELLLDP + F+E+ Sbjct: 22 MLAKLADLDAEHAKALAGGGEKYVARHRKRGKLLARERIELLLDPDTPFLELSPLAAW-G 80 Query: 62 TEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAG 121 +E+ + ++TG G + G + A D TV GG+ K R ++AL Sbjct: 81 SEYTVGA------SLVTGIGVVEGVECLITANDPTVRGGASNPWSLKKALRANDIALANR 134 Query: 122 APVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSPAIG 180 P I L +SGGA + + G IF+ T LS +P I + G G Y P + Sbjct: 135 LPCISLVESGGADLPSQKEIFIPGGAIFRDLTRLSAAGIPTIAVVFGNSTAGGAYIPGMS 194 Query: 181 DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL 240 D +MV + +F+ GP +VK TG + LGGA +HA+ SG A + + + Sbjct: 195 DHTIMVKERAK-VFLGGPPLVKMATGEESDDESLGGAEMHARTSGLADHFAVDEPDALRQ 253 Query: 241 IKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENG 300 +R+++ L P P + P EL IVP D +D R+VI IVD Sbjct: 254 ARRVVARLNHRKAYADP--PPAEPPMYDPEELLGIVPGDLRTPFDPREVIARIVDAS--- 308 Query: 301 NPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN 360 DF E +P + + G+ ++G VGI+AN GVL + S K A+F++ + + Sbjct: 309 --DFDEFKPLYGTSLTTGWAALHGYPVGILAN----ARGVLFSEESQKAAQFIQLANQRD 362 Query: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSK 420 IP++ + GY+ G + E GII+HGA ++ A + + VP ++V+L +YG + M + Sbjct: 363 IPLLFLHNTTGYMVGREYEQGGIIKHGAMMINAVSNSRVPHLSVLLGASYGAGHYGMCGR 422 Query: 421 HLGADFVFAWPTAEIAVMGPE---GAANIIFRKEIAKAENP-----EEFRKQKIQEYREK 472 F+FAWP+A+ AVMGP+ G +I+ R+ A P + + +++ E Sbjct: 423 AYDPRFLFAWPSAKSAVMGPQQLAGVLSIVARQSAAAKGQPYDDEGDAALRAMVEQQIES 482 Query: 473 FANPYVAASRGYIDDVIDPAETRAKIVMALEAL 505 + P + R Y D VIDP +TR + + L A+ Sbjct: 483 ESLPMFLSGRLYDDGVIDPRDTRTVLGLCLSAV 515 >dbj|BAB16296.1| (AB039884) acetyl-CoA carboxylase carboxyltransferase [Myxococcus xanthus] Length = 538 Score = 238 bits (600), Expect = 2e-61 Identities = 167/528 (31%), Positives = 262/528 (48%), Gaps = 27/528 (5%) Query: 3 MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRA 61 M+ +V +L K+ + A +K H +G+L RER+ LLLD GS F+E+ + Sbjct: 22 MLARVSELRAIEAKVRNTENQ-AKEKFHKRGQLLPRERLMLLLDRGSPFLELSTLCGYGY 80 Query: 62 TEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAG 121 + L I G G ++G V+ + + GG+ K R LALE Sbjct: 81 HDDS--DGSLAGGNSIIGIGYVSGVRCIVFVNNSAIKGGTASPWGVQKALRAQALALENK 138 Query: 122 APVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSPAIG 180 P++ L +SGGA + + GE F LS +PQ+T + G G Y P + Sbjct: 139 LPMVSLVESGGANLMYQQEIFIPGGETFYNQARLSAAGIPQVTVVHGSSTAGGAYLPGLS 198 Query: 181 DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL 240 D+++MV + +F+ GP ++KA TG T +LGGA +HA +G A + + D + I + Sbjct: 199 DYVVMVKKKAK-VFLAGPPLLKAATGEVATDEELGGAQMHATVAGTADYLAEDDADAIRM 257 Query: 241 IKRLLSYLPSNNMEKPPRVKPK-DEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDEN 299 + +++ L N + PP +P EP EL VP D K YD R+VI IVD E Sbjct: 258 AREIVAKL-GWNAQLPPTERPAYAEPVYSPDELCGAVPVDYRKPYDCREVIARIVDGSE- 315 Query: 300 GNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAF 359 F + + + V G+ + G +GI+ NN G + + K A+F++ C Sbjct: 316 ----FTGFKDEYDAHTVCGWANLYGHPLGIIGNN-----GPISPQGATKAAQFIQLCCQK 366 Query: 360 NIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGS 419 + PI+ + GYL G E GI++HGAK++ A A ATVP +TV++ A+G M Sbjct: 367 DTPILYLQNTTGYLVGTQPEQGGIVKHGAKMIQAVANATVPQLTVLIGGAFGAGNYGMCG 426 Query: 420 KHLGADFVFAWPTAEIAVMGPEGAA---NIIFRKEIAKAEN--PEEFRK---QKIQEYRE 471 + F+F WP + AVMG E AA +I+F +++A+ EE K Q I + + Sbjct: 427 RPFHPRFIFGWPNSRTAVMGGEQAAKVMSIVFGEKLARQGQVVDEEQLKAFCQPIIDQFD 486 Query: 472 KFANPYVAASRGYIDDVIDPAETRAKIVMALEAL-ENKRVKLPPKKHG 518 K ++P+ ++R + D +IDP +TR + AL E KR ++ P G Sbjct: 487 KESHPFNCSARMFDDGLIDPRDTRRVLGFALSVCREAKRRQVHPNTFG 534 >pir||C83284 probable biotin-dependent carboxylase PA2888 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9948979|gb|AAG06276.1|AE004715_2 (AE004715) probable biotin-dependent carboxylase [Pseudomonas aeruginosa] Length = 538 Score = 235 bits (592), Expect = 1e-60 Identities = 140/448 (31%), Positives = 229/448 (50%), Gaps = 18/448 (4%) Query: 3 MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRA 61 M+ V + +K+L E A K +G+L RER+ LLLDPG+ F+E+ ++ Sbjct: 22 MLAAVAGFRELEQKVLDKAAE-ARPKFEKRGQLLPRERLALLLDPGAPFLELSSLAGYKL 80 Query: 62 TEFGMDKRDLPADG-VITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA 120 + DK A G +I G G I G V A + + GG++ K R+ ++A+E Sbjct: 81 HD---DKDGTQAGGGIIAGIGYIAGVRCLVSASNSAIKGGTISPTGLKKTLRLQQIAMEN 137 Query: 121 GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSPAI 179 PV+ L +SGGA + + F +S + +PQ+T + G G Y P + Sbjct: 138 KLPVVTLTESGGANLNYAAEIFVEGARGFANQARISAMGIPQVTVVHGSSTAGGAYQPGL 197 Query: 180 GDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIG 239 D++++V + MF+ GP ++KA TG + +LGGA +HAQ +G A + ++D + + Sbjct: 198 SDYVVVVRGKAK-MFLAGPPLLKAATGEIASDEELGGAELHAQVAGTAEYLAENDADGVR 256 Query: 240 LIKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDEN 299 L + ++ LP N + EP EL +VP DP K YDVR+++ I D E Sbjct: 257 LAREIVGMLPWNAQLPARPARSWREPLYPVEELLGVVPADPKKPYDVREIVARIADGSE- 315 Query: 300 GNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAF 359 FL+ + F V G RI G G++ NN G + + K A+F++ C+ Sbjct: 316 ----FLDFKNEFDGQTVCGHLRIEGHACGLIGNN-----GPITPQGAAKAAQFIQLCEQS 366 Query: 360 NIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGS 419 N P++ + G++ G + E +G+I+HG+K++ A A A VP +T+++ +YG AM Sbjct: 367 NTPLLFLHNTTGFMVGTESERQGVIKHGSKMIQAVANARVPKLTLVVGGSYGAGNYAMCG 426 Query: 420 KHLGADFVFAWPTAEIAVMGPEGAANII 447 + L F+FAWP + AVMG A ++ Sbjct: 427 RGLDPRFIFAWPNSRTAVMGGAQAGKVL 454 >pir||B83471 probable pyruvate carboxylase PA1400 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9947346|gb|AAG04789.1|AE004569_7 (AE004569) probable pyruvate carboxylase [Pseudomonas aeruginosa] Length = 1095 Score = 224 bits (565), Expect = 2e-57 Identities = 172/524 (32%), Positives = 254/524 (47%), Gaps = 59/524 (11%) Query: 9 DLYQRRKKILQMGGE---EAIKKQHDKGKLTARERIELLLDPGSFVEIGMFV-----KHR 60 DL + ++ +G E +A+ ++ G+ TARE + LLD GSF E G F + R Sbjct: 581 DLAEVLERQAALGDERRPQALARRRKTGQRTARENVLDLLDEGSFSEYGGFALAAQRRRR 640 Query: 61 ATEFGMDKRDLPADGVITGYGTINGRLV-------FVYAQDFTVMGGSLGEMHAMKIKRI 113 + E ++ PADG++ G GT+ V A D+TV G+ G M+ K R+ Sbjct: 641 SAEELLELS--PADGLVAGTGTVGAASFGVQAARCLVLAYDYTVFAGTQGVMNHKKTDRL 698 Query: 114 MELALEAGAPVIGLNDSGGARIQE----GVDSLKGYGEIFKMNTILSGVVPQITAIMGPC 169 + LA + P++ + GG R + GV L + F LSG+VP + + G C Sbjct: 699 LGLAEQWRLPLVLFAEGGGGRPGDTDFVGVAGLDCH--TFVGMARLSGLVPLVGVVSGRC 756 Query: 170 AGGAVYSPAIGDFILMVDNPSTFMFITGPQVVKA-----VTGVDVTPVQLGGALVHAQKS 224 G D I+ + + M GP +++ +V P + G + Sbjct: 757 FAGNAALLGCCDVIIATRDATIGM--AGPAMIEGGGLGRFAAEEVGPTGVQGP------N 808 Query: 225 GQAHLIGKSDEEVIGLIKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAY 284 G ++ + + E + + +R L Y D EL +VP++ +AY Sbjct: 809 GVIDVLVEDEAEAVAVARRYLGYFQG---------PLPDWSCADQRELRHLVPENRLRAY 859 Query: 285 DVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDID 344 D+RQ I + DR LEL+ FAP V RI G+ G++ANNP HL G +D Sbjct: 860 DIRQAIEVLADRGS-----VLELRRQFAPGLVTALLRIEGRAFGLIANNPGHLGGAIDAA 914 Query: 345 SSDKIARFVRFCDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTV 404 + DK ARF++ CDAF+IPIV+ D PG++ G + E + +RH +++ + A TVP TV Sbjct: 915 AGDKAARFMQLCDAFDIPIVSLCDTPGFMVGPEAEKQATVRHVSRMFVSAASLTVPFFTV 974 Query: 405 ILRKAYG-GAY-LAMGSKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEE-- 460 +LRK YG GA +A GS H F AWP+ E MG EGA + F KE+A E+P+ Sbjct: 975 VLRKGYGLGAQAMAAGSFH-SPLFTVAWPSGEFGAMGLEGAVRLGFAKELAAEEDPQRRE 1033 Query: 461 --FRKQKIQEYREKFANPYVAASRGYIDDVIDPAETRAKIVMAL 502 FR + YR AS ID VIDPAETRA ++ L Sbjct: 1034 ALFRGMVDKAYRN--GKALNMASYLEIDAVIDPAETRAWLLRGL 1075 >pir||C75585 carboxylase - Deinococcus radiodurans (strain R1) >gi|6460763|gb|AAF12468.1|AE001863_93 (AE001863) carboxylase [Deinococcus radiodurans] Length = 1091 Score = 215 bits (542), Expect = 1e-54 Identities = 161/497 (32%), Positives = 245/497 (48%), Gaps = 41/497 (8%) Query: 25 AIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGMDKRD-----LPADGVITG 79 A++K+H GKLTARE + LLD GSF E G A + G + PADG+ITG Sbjct: 599 AVEKRHAAGKLTARENVAALLDAGSFNEHGALAL--AAQRGRRSEEELLALSPADGLITG 656 Query: 80 YGTING------RLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGA 133 GT+N V A D+TV+ G+ G + K+ R++ LA + P++ + GG Sbjct: 657 VGTVNAGQFPDTAACAVAAYDYTVLAGTQGYFNHHKLDRLIALAGQWKWPLVLFAEGGGG 716 Query: 134 RIQEGVDSLKG--YGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVDNPST 191 R + + F LSG VP + G C G D ++ + S Sbjct: 717 RPGDTDMPVAAALVTPTFLNFAALSGQVPLVGVAAGACFAGNAALLGCCDVVIATRDSS- 775 Query: 192 FMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSN 251 + + GP +++ V +G A V AQK G L+ ++D E L +R L+Y + Sbjct: 776 -IGLGGPAMIEGGGLGVVAAGDIGPAEVLAQK-GVVDLLAENDAEANELARRYLTYFQGD 833 Query: 252 NMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYF 311 V + +R EL ++P +AYDVR +++ + D LEL+ F Sbjct: 834 -------VTGWEAADQR--ELRWVIPQVRKRAYDVRALLHLLADTGS-----VLELRRAF 879 Query: 312 APNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPG 371 AP + RI G+ G++AN+P L G +D +DK ARF+ CD +P+++ VD PG Sbjct: 880 APGLLTALVRIGGKAFGVIANDPAVLGGAIDAAGADKAARFLNLCDTHRLPVLSLVDTPG 939 Query: 372 YLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYG-GAY-LAMGSKHLGADFVFA 429 ++ G E+ G +RH +++ A+ TVP V+ R+AYG GA +A GS H A + Sbjct: 940 FMVGPASEAEGAVRHVSRLFVRAAKLTVPFFAVVTRRAYGLGAQAMAAGSLHAPA-LTVS 998 Query: 430 WPTAEIAVMGPEGAANIIFRKEIAKAENPEE----FRKQKIQEYREKFANPYVAASRGYI 485 WP E MG EGA + +R+E+A +P+E ++K Q Y + A+ + Sbjct: 999 WPGGEFGPMGLEGAVRLGYRRELAAVSDPQEREALYQKLVAQAYAQ--GEAVNVAAHLEV 1056 Query: 486 DDVIDPAETRAKIVMAL 502 D VIDPAETR ++ AL Sbjct: 1057 DAVIDPAETRNWLLRAL 1073 >pir||T45098 probable propionyl-coA carboxylase beta chain [imported] - Mycobacterium smegmatis (fragment) >gi|2073536|gb|AAC45278.1| (U46844) putative propionyl-coA carboxylase beta chain [Mycobacterium smegmatis] Length = 210 Score = 197 bits (495), Expect = 3e-49 Identities = 99/209 (47%), Positives = 135/209 (64%), Gaps = 2/209 (0%) Query: 316 VIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPGYLPG 375 + F R++G VG++AN P+ L+G +D ++SDK A F+RFCD++N+P+V VD PG +PG Sbjct: 2 ITAFARVDGHPVGVIANQPMVLSGAIDNEASDKAASFIRFCDSYNLPLVFVVDTPGAMPG 61 Query: 376 VDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAWPTAEI 435 V +E GII+ G + A EA VP VTVI+RKAYGG Y MGSK L AD FAWPTA I Sbjct: 62 VAEEKGGIIKRGGRFFNAIVEADVPKVTVIIRKAYGGGYAVMGSKQLSADLNFAWPTARI 121 Query: 436 AVMGPEGAANIIFRK-EIAKAENPEEFRKQKIQEYREKFANPYVAASRGYIDDVIDPAET 494 AV+G EGAA ++ ++ A ++ R I+ Y A P++AA RGYID VI P ET Sbjct: 122 AVIGAEGAAQLLVKRFPDPNAPEVQKIRDDFIEGYNLNMATPWIAAERGYIDAVIQPHET 181 Query: 495 RAKIVMALEALENKR-VKLPPKKHGNIPL 522 R + +L L +K+ +KHG +PL Sbjct: 182 RLLLRKSLRLLRDKQNGPKVQRKHGLLPL 210 >gb|AAC69174.1| (AF030576) methylmalonyl-CoA decarboxylase alpha subunit [Acidaminococcus fermentans] Length = 154 Score = 194 bits (489), Expect = 2e-48 Identities = 98/162 (60%), Positives = 119/162 (72%), Gaps = 8/162 (4%) Query: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSK 420 IP++ VDVPG+LPG DQE GIIRHGAK+LYAY EATVP +T++ RKAYGGAYLAM ++ Sbjct: 1 IPLINIVDVPGFLPGTDQEYGGIIRHGAKMLYAYCEATVPKITLVTRKAYGGAYLAMCAQ 60 Query: 421 HLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAA 480 LGAD V AWPTAEIAVMGP+GAA IIFRK+ P+ +QK QEY FA PY AA Sbjct: 61 DLGADHVIAWPTAEIAVMGPQGAAKIIFRKD------PDV--EQKTQEYITNFATPYYAA 112 Query: 481 SRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522 G ++ VI+P TR ++ AL L++K+ P KKHGNIPL Sbjct: 113 KHGMVEMVIEPKTTRPILIKALRMLKSKQEDRPTKKHGNIPL 154 >gb|AAA60036.1| (M13573) propionyl-CoA carboxylase beta chain (EC 6.4.1.3) [Homo sapiens] Length = 155 Score = 185 bits (464), Expect = 1e-45 Identities = 94/155 (60%), Positives = 114/155 (72%), Gaps = 5/155 (3%) Query: 263 DEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIGFGRI 322 D R PEL IVP + KAY++ +I+++VD E F E+ P +A N ++GF R+ Sbjct: 5 DPSDRLVPELDTIVPLESTKAYNMVDIIHSVVDERE-----FFEIMPNYAKNIIVGFARM 59 Query: 323 NGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPGYLPGVDQESRG 382 NG+TVGIV N P +G LDI+SS K ARFVRFCDAFNIP++TFVDVPG+LPG QE G Sbjct: 60 NGRTVGIVGNQPKVASGCLDINSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGG 119 Query: 383 IIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAM 417 IIRHGAK+LYA+AEATVP VTVI RKAYGGAY M Sbjct: 120 IIRHGAKLLYAFAEATVPKVTVITRKAYGGAYDVM 154 >emb|CAA74219.1| (Y13917) yngE [Bacillus subtilis] Length = 280 Score = 169 bits (423), Expect = 9e-41 Identities = 102/289 (35%), Positives = 156/289 (53%), Gaps = 12/289 (4%) Query: 4 MEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATE 63 M+ ++ +R ++I + G E+ + +KGKL RER+ LL D +E F + + Sbjct: 1 MDYEKERTERAERIRKGGAEKYHQSNREKGKLFVRERLSLLFDDDIELEDAFFAECMSD- 59 Query: 64 FGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAP 123 LPADGV+T G I G+ V V A D TV GS G KI RI E+A + P Sbjct: 60 ------GLPADGVVTAIGKIGGQTVCVMANDSTVKAGSWGAKTVEKIIRIQEIAEKLNCP 113 Query: 124 VIGLNDSGGARIQEGVD---SLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG 180 +I L DS GARI + ++ +G G IF LSG +PQI + GP A G Y PA Sbjct: 114 LIYLVDSAGARITDQINVFPGRRGAGRIFYNQVKLSGRIPQICLLFGPSAAGGAYIPAFC 173 Query: 181 DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL 240 D ++MVD ++ M++ P++ + V G V+ ++GGA +H SG ++ +++EE I L Sbjct: 174 DIVVMVDGNAS-MYLGSPRMAEMVIGEKVSLEEMGGARMHCSISGCGDILAETEEEAIQL 232 Query: 241 IKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQV 289 ++ LSY P+N EK P + K P L D++P + N +D+ ++ Sbjct: 233 VRAYLSYFPANFQEKAP-IHEKRPPKHFETPLADVIPQNQNAPFDMHEL 280 >sp|Q06700|GCDA_ACIFE GLUTACONYL-COA DECARBOXYLASE A SUBUNIT (CARBOXYLTRANSFERASE) >gi|321991|pir||S29787 UDPgalacturonate decarboxylase (EC 4.1.1.67) alpha chain - Acidaminococcus fermentans >gi|49182|emb|CAA49210.1| (X69435) Glutaconyl-CoA decarboxylase [Acidaminococcus fermentans] Length = 587 Score = 128 bits (318), Expect = 2e-28 Identities = 129/538 (23%), Positives = 220/538 (39%), Gaps = 56/538 (10%) Query: 8 EDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGMD 67 E+++Q K+ + G +A + +G+LTA +RIE L++PGS+ + + + G Sbjct: 36 EEIHQLIKEAQEAGKADA--DVNKRGELTALQRIEKLVEPGSWRPLNTLFNPQGNKNG-- 91 Query: 68 KRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGL 127 + ++ G G +NG+ V A D + G+ A + R + A P++ + Sbjct: 92 -----SVAIVKGLGRVNGKWCVVVASDNKKLAGAWVPGQAECLLRASDTAKTLHVPLVYV 146 Query: 128 NDSGGARIQEG---VDSLKGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVY---SPAI- 179 + G + E + +G G F N L+ + +P I I G G Y SP + Sbjct: 147 LNCSGVKFDEQEKVYPNRRGGGTPFFRNAELNQLGIPVIVGIYGTNPAGGGYHSISPTVI 206 Query: 180 -----------GDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAH 228 G I+ NP + + + + G +H ++G Sbjct: 207 IAHEKANMAVGGAGIMGGMNPKGHVDLEYANEIADMVDRTGKTEPPGAVDIHYTETGFMR 266 Query: 229 LIGKSDEEVIGLIKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQ 288 + S+E V+ IK+ + LP + E RV P +LY +VP + +AYD+ Sbjct: 267 EVYASEEGVLEGIKKYVGMLPKYDPEFF-RVDDPKAPAFPADDLYSMVPLNDKRAYDIYN 325 Query: 289 VIYAIVDRDENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVAN--------------NP 334 VI + D N + E + + P V G ++NG VG+VAN Sbjct: 326 VIARLFD-----NSELHEYKKGYGPEMVTGLAKVNGLLVGVVANVQGLLMNYPEYKAAGS 380 Query: 335 IHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAY 394 + + G L K+ FV C +PIV D G G D E ++ G ++Y+ Sbjct: 381 VGIGGKLYRQGLVKMNEFVTLCARDRLPIVWIQDTTGIDVGNDAEKAELLGLGQSLIYSI 440 Query: 395 AEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAWPTA--EIAVMGPEGAANIIFRKEI 452 + +P + LRK A+ +G F+ TA EIAVM E AA ++ + + Sbjct: 441 QTSHIPQFEITLRKGTAAAHYVLGGPQGNDTNAFSIGTAATEIAVMNGETAATAMYSRRL 500 Query: 453 AKAENPEEFRKQKIQEYREKF------ANPYVAASRGYIDDVIDPAETRAKIVMALEA 504 AK + + I + + P V A G +D+++D + R + EA Sbjct: 501 AKDRKAGKDLQPTIDKMNNLIQAFYTKSRPKVCAELGLVDEIVDMNKIRGYVEAFTEA 558 >emb|CAC00930.1| (AL390935) probable propionyl-coa carboxylase beta chain, mitochondrial precursor(ec 6.4.1.3) [Leishmania major] Length = 106 Score = 108 bits (268), Expect = 1e-22 Identities = 55/110 (50%), Positives = 71/110 (64%), Gaps = 5/110 (4%) Query: 259 VKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIG 318 V D +R L +VP + +AYD+R I+ ++D+D F E+QP FA N + G Sbjct: 2 VPTADNRYRDVSSLNTVVPVEVKEAYDMRDAIFPVIDQDS-----FFEIQPQFAKNIICG 56 Query: 319 FGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVD 368 F R+ G++V I+AN P AGVLDIDSS K AR VRF DAFNIPI+TFVD Sbjct: 57 FARVEGRSVCIIANQPKVQAGVLDIDSSVKAARMVRFADAFNIPIITFVD 106 >emb|CAA19885.1| (AL031032) putative protein (fragment) [Arabidopsis thaliana] Length = 224 Score = 94.0 bits (230), Expect = 4e-18 Identities = 57/154 (37%), Positives = 82/154 (53%), Gaps = 9/154 (5%) Query: 7 VEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRATEFG 65 + +L KK+L GGEEA+K+ + KL RERI+ LLDPGS F+E+ H E Sbjct: 72 LSELRSHIKKVLAGGGEEAVKRNRSRNKLLPRERIDRLLDPGSSFLELSQLAGHELYE-- 129 Query: 66 MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125 LP+ G+ITG G I+GR+ A D TV GG+ + K R E+A P I Sbjct: 130 ---EPLPSGGIITGIGPIHGRICMFMANDPTVKGGTYYPITIKKHLRAQEIAARCRLPCI 186 Query: 126 GLNDSGGARIQEGVD---SLKGYGEIFKMNTILS 156 L DSGGA + + + + +G +F +++S Sbjct: 187 YLVDSGGAYLPKQAEVFPDKENFGRVFYNESVMS 220 >pir||H81687 acetyl-coenzyme A carboxylase carboxyl transferase, beta chain TC0566 [imported] - Chlamydia muridarum (strain Nigg) >gi|7190606|gb|AAF39403.1| (AE002324) acetyl-coenzyme A carboxylase carboxyl transferase, beta subunit [Chlamydia muridarum] Length = 283 Score = 82.7 bits (201), Expect = 9e-15 Identities = 61/193 (31%), Positives = 101/193 (51%), Gaps = 22/193 (11%) Query: 34 KLTARERIELLLDPGSFVEIGMFVKHRATEFGMD------------KRDLPADGVITGYG 81 +++A ERI LL D GS+ + +K + +D K + ++GV+ G Sbjct: 54 RISASERIALLADEGSWNPLFSELKSQDPLHFVDTDTYSNRLEKARKNNPDSEGVLVGNC 113 Query: 82 TINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDS 141 TI G V + DF+ M GS+G + K+ R++E A+++ PVI ++ SGGAR+QE V S Sbjct: 114 TIGGHSVALAVMDFSFMAGSMGAVVGEKLTRLIEKAIDSRWPVIIVSASGGARMQESVFS 173 Query: 142 LKGYGEIFKMNTILSGV----VPQITAIMGPCAGGAVYS-PAIGDFILMVDNPSTFMFIT 196 L ++ K + L+ + +P I+ + P +GG S ++GD I + P + Sbjct: 174 LM---QMAKTSAALAKLHEAKLPYISVLTNPTSGGVTASFASLGDVI--IAEPKALICFA 228 Query: 197 GPQVVKAVTGVDV 209 GP+VV V G D+ Sbjct: 229 GPRVVSQVIGEDL 241 >gb|AAB97629.1| (AF121266) malonate decarboxylase beta subunit [Acinetobacter calcoaceticus] Length = 295 Score = 79.6 bits (193), Expect = 8e-14 Identities = 60/182 (32%), Positives = 91/182 (49%), Gaps = 14/182 (7%) Query: 36 TARERIELLLDPGSFVEIGMFVKHRATEFG--MDKRDLPA---DGVITGYGTINGRLVFV 90 TAR RI+ ++D SF EI +K E + D+P DGVI G IN + + Sbjct: 14 TARARIQAVVDENSFKEI---LKPTEIEVSPHLSALDIPGSFDDGVIIGTAAINQTPIHI 70 Query: 91 YAQDFTVMGGSLGEMHAMKIKRIMELAL-EAGAPVIGLNDSGGARIQEGVDSLKGYGEIF 149 AQ+ MGG++GE+H KI ++ A+ + V+ DSGG R+ E L EI Sbjct: 71 IAQEGQFMGGAVGEIHGAKIVGLLHKAIQDQSQAVVFFVDSGGVRLHEANAGLIAISEIM 130 Query: 150 K-MNTILSGVVPQITAIMGPCA--GGAVYSPAIGDFILMVDNPSTFMFITGPQVVKAVTG 206 + M + +P IT I G C GG S + I+M + + ++GP+V++ V G Sbjct: 131 RAMLQVRHAGIPIITVIGGTCGAFGGMGISACLSSTIIMTEEGR--LALSGPEVIETVKG 188 Query: 207 VD 208 V+ Sbjct: 189 VE 190 >pir||C72124 acetyl-coenzyme A carboxylase carboxyl transferase, beta chain CP0717 [imported] - Chlamydophila pneumoniae (strains CWL029 and AR39) >gi|4376314|gb|AAD18211.1| (AE001591) AcCoA Carboxylase/Transferase Beta [Chlamydophila pneumoniae CWL029] >gi|7189631|gb|AAF38523.1| (AE002230) acetyl-coenzyme A carboxylase carboxyl transferase, beta subunit [Chlamydophila pneumoniae AR39] >gi|8978432|dbj|BAA98269.1| (AP002545) AcCoA carboxylase/transferase beta [Chlamydophila pneumoniae J138] Length = 308 Score = 79.6 bits (193), Expect = 8e-14 Identities = 62/193 (32%), Positives = 97/193 (50%), Gaps = 22/193 (11%) Query: 34 KLTARERIELLLDPGSFVEIGMFVKHRATEFGMD------------KRDLPADGVITGYG 81 ++TA ER++LL D S+ + +K + +D K ++GVI G Sbjct: 54 RITAIERVKLLADKDSWRPLYTDLKSQDPLEFIDTDTYANRLEKARKNTTESEGVIVGIC 113 Query: 82 TINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDS 141 TI V + DF M GS+G + K+ R++E A+E PVI ++ SGGAR+QE V S Sbjct: 114 TIGLHPVALAVMDFNFMAGSMGAVVGEKLTRLIEEAIETRLPVIIVSASGGARMQESVFS 173 Query: 142 LKGYGEIFKMNTILSGV----VPQITAIMGPCAGGAVYS-PAIGDFILMVDNPSTFMFIT 196 L ++ K + L+ + +P I+ + P +GG S A+GD I + P + Sbjct: 174 LM---QMVKTSAALAKLHEAGLPYISVLTNPTSGGVTASFAALGDII--IAEPKALICFA 228 Query: 197 GPQVVKAVTGVDV 209 GP+VV V G D+ Sbjct: 229 GPRVVAQVIGEDL 241 >emb|CAC00894.1| (AL390935) probable propionyl-coa carboxylase beta chain homolog [Leishmania major] Length = 54 Score = 79.2 bits (192), Expect = 1e-13 Identities = 39/54 (72%), Positives = 42/54 (77%) Query: 386 HGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAWPTAEIAVMG 439 HGAK+LYAYAEATVP VT+I R AYGGAY M SKHL D +A P AEIAVMG Sbjct: 1 HGAKLLYAYAEATVPXVTIITRXAYGGAYDVMSSKHLRGDGXYAXPRAEIAVMG 54 >sp|P08193|ACCD_ECOLI ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (ACCASE BETA CHAIN) >gi|7428518|pir||XMECBD acetyl-CoA carboxylase (EC 6.4.1.2), carboxyltransferase beta chain [validated] - Escherichia coli >gi|1788655|gb|AAC75376.1| (AE000320) acetylCoA carboxylase, carboxytransferase component, beta subunit [Escherichia coli K12] >gi|1799709|dbj|BAA16173.1| (D90863) acetyl-CoA carboxylase (EC 6.4.1.2), carboxyltransferase beta chain [Escherichia coli] Length = 304 Score = 77.6 bits (188), Expect = 3e-13 Identities = 72/243 (29%), Positives = 112/243 (45%), Gaps = 28/243 (11%) Query: 34 KLTARERIELLLDPGSFVEIGMFV------------KHRATEFGMDKRDLPADGVITGYG 81 ++TAR R+ LLD GS VE+G + K++ K D ++ G Sbjct: 54 RMTARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKETGEKDALVVMKG 113 Query: 82 TINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDS 141 T+ G V A +F MGGS+G + + R +E ALE P+I + SGGAR+QE + S Sbjct: 114 TLYGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLICFSASGGARMQEALMS 173 Query: 142 LKGYGEIFKMNTILSGV----VPQITAIMGPCAGGAVYSPA-IGDFILMVDNPSTFMFIT 196 L ++ K + L+ + +P I+ + P GG S A +GD L + P + Sbjct: 174 LM---QMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGD--LNIAEPKALIGFA 228 Query: 197 GPQVVKAVTGVDVTP-VQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRL--LSYLPSNNM 253 GP+V++ + P Q L+ + G +I + E + L L L LP+ N Sbjct: 229 GPRVIEQTVREKLPPGFQRSEFLI---EKGAIDMIVRRPEMRLKLASILAKLMNLPAPNP 285 Query: 254 EKP 256 E P Sbjct: 286 EAP 288 >pir||B71534 probable accoa carboxylase/transferase beta - Chlamydia trachomatis (serotype D, strain UW3/Cx) >gi|3328707|gb|AAC67886.1| (AE001301) AcCoA Carboxylase/Transferase Beta [Chlamydia trachomatis] Length = 308 Score = 76.9 bits (186), Expect = 5e-13 Identities = 55/169 (32%), Positives = 91/169 (53%), Gaps = 13/169 (7%) Query: 46 DPGSFVEIGMFVKHRATEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEM 105 DP +FV+ + +R + D D ++GV+ G TI V + DF+ M GS+G + Sbjct: 81 DPLNFVDTDTY-PNRLEKARKDNPD--SEGVLVGVCTIGSHPVALAVMDFSFMAGSMGAV 137 Query: 106 HAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGV----VPQ 161 K+ R++E A+++ PVI ++ SGGAR+QE V SL ++ K + L+ + +P Sbjct: 138 VGEKLTRLIEKAIDSRLPVIIVSASGGARMQESVFSLM---QMAKTSAALAKLHEAKLPY 194 Query: 162 ITAIMGPCAGGAVYS-PAIGDFILMVDNPSTFMFITGPQVVKAVTGVDV 209 I+ + P +GG S ++GD I + P + GP+VV V G D+ Sbjct: 195 ISVLTNPTSGGVTASFASLGDVI--IAEPKALICFAGPRVVSQVIGEDL 241 >pir||E71875 acetyl-coenzyme A carboxylase chain B - Helicobacter pylori (strain J99) >gi|4155465|gb|AAD06468.1| (AE001518) ACETYL-COENZYME A CARBOXYLASE SUBUNIT B [Helicobacter pylori J99] Length = 289 Score = 76.1 bits (184), Expect = 9e-13 Identities = 61/198 (30%), Positives = 92/198 (45%), Gaps = 20/198 (10%) Query: 28 KQHDKGKLTARERIELLLDPGSFVEIGMFV--------------KHRATEFGMDKRDLPA 73 K H ++ A ERIE L D GSF E + K R ++ +KR Sbjct: 52 KCHYHFRMNATERIEFLCDVGSFEEFDKHLRPNDPLNFVDKESYKQRIKKY--EKRTNRP 109 Query: 74 DGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGA 133 VI+G IN + + DF+ MGGSLG + KI R + A+ ++ ++ SGGA Sbjct: 110 SSVISGEAKINRMPLQIVVFDFSFMGGSLGSVEGEKIVRAINRAVAKKEALLIVSASGGA 169 Query: 134 RIQEGVDSLKGYGEI-FKMNTILSGVVPQITAIMGPCAGGAVYSPA-IGDFILMVDNPST 191 R+QE SL + +N + +P I+ + P GG S A +GD L++ P Sbjct: 170 RMQESTYSLMQMAKTSAALNRLSEAKLPFISLLSDPTYGGVSASFAFLGD--LIIAEPGA 227 Query: 192 FMFITGPQVVKAVTGVDV 209 + GP+V+K G D+ Sbjct: 228 MIGFAGPRVIKQTIGADL 245 >pir||F64638 acetyl-CoA carboxylase beta subunit - Helicobacter pylori (strain 26695) >gi|2314089|gb|AAD07995.1| (AE000604) acetyl-CoA carboxylase beta subunit (accD) [Helicobacter pylori 26695] Length = 289 Score = 75.7 bits (183), Expect = 1e-12 Identities = 61/198 (30%), Positives = 92/198 (45%), Gaps = 20/198 (10%) Query: 28 KQHDKGKLTARERIELLLDPGSFVEIGMFV--------------KHRATEFGMDKRDLPA 73 K H ++ A ERIE L D GSF E + K R ++ +KR Sbjct: 52 KCHYHFRMKAAERIEFLCDVGSFEEFDKHLRPNDPLNFVDKESYKQRIKKY--EKRTNRP 109 Query: 74 DGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGA 133 VI+G IN + + DF+ MGGSLG + KI R + A+ ++ ++ SGGA Sbjct: 110 SSVISGEAKINRMPLQIVVFDFSFMGGSLGSVEGEKIVRAINRAVAKREALLIVSASGGA 169 Query: 134 RIQEGVDSLKGYGEI-FKMNTILSGVVPQITAIMGPCAGGAVYSPA-IGDFILMVDNPST 191 R+QE SL + +N + +P I+ + P GG S A +GD L++ P Sbjct: 170 RMQESTYSLMQMAKTSAALNRLSEAKLPFISLLSDPTYGGVSASFAFLGD--LIIAEPGA 227 Query: 192 FMFITGPQVVKAVTGVDV 209 + GP+V+K G D+ Sbjct: 228 MIGFAGPRVIKQTIGADL 245 >gb|AAG24832.1| (AF294436) acetyl-CoA carboxylase beta subunit [Bacillus pumilus] Length = 196 Score = 75.7 bits (183), Expect = 1e-12 Identities = 59/194 (30%), Positives = 92/194 (47%), Gaps = 22/194 (11%) Query: 35 LTARERIELLLDPGSFVEIGMFV------------KHRATEFGMDKRDLPADGVITGYGT 82 +TAR R+ LLD GS VE+G + K++ K D ++ GT Sbjct: 1 MTARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKETGEKDALVVMKGT 60 Query: 83 INGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDSL 142 + G V A +F MGGS+G + + R +E ALE P+I + SGGAR+QE + SL Sbjct: 61 LYGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLICFSASGGARMQEALMSL 120 Query: 143 KGYGEIFKMNTILSGV----VPQITAIMGPCAGGAVYSPA-IGDFILMVDNPSTFMFITG 197 ++ K + L+ + +P I+ + P GG S A +GD L + P + G Sbjct: 121 M---QMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGD--LNIAEPKALIGFAG 175 Query: 198 PQVVKAVTGVDVTP 211 P+V++ + P Sbjct: 176 PRVIEQTVREKLPP 189 >pir||S41121 acetyl-CoA carboxylase (EC 6.4.1.2) - human >gi|452316|emb|CAA48770.1| (X68968) acetyl-CoA carboxylase [Homo sapiens] >gi|740964|prf||2006242A Ac-CoA carboxylase [Homo sapiens] Length = 2339 Score = 74.5 bits (180), Expect = 3e-12 Identities = 89/394 (22%), Positives = 165/394 (41%), Gaps = 39/394 (9%) Query: 86 RLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDSLKGY 145 + +++ QD+T + SL +H I+ E G + D G GV++L+G Sbjct: 1741 KYLYLTPQDYTRIS-SLNSVHCKHIE-------EGGESRYMITDIIGKDDGLGVENLRGS 1792 Query: 146 GEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFMFITGPQVVKAVT 205 G I +++ + I+ + G Y +G ++ V+N + + +TG + V Sbjct: 1793 GMIAGESSLAYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVEN--SHIILTGASALNKVL 1850 Query: 206 GVDV--TPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSNNMEKPPRVKPKD 263 G +V + QLGG + +G +H+ D E + I LSY+P +N P + P D Sbjct: 1851 GREVYTSNNQLGGVQI-MHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTD 1909 Query: 264 EPFRRTPELYDIVPDDPN--KAYDVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIGFGR 321 R L P DP A + + F E+ +A V G R Sbjct: 1910 PIDREIEFLPSRAPYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRAR 1969 Query: 322 INGQTVGIVA-----------NNPIHLAGVLDI----------DSSDKIARFVRFCDAFN 360 + G VG++A +P +L I DS+ K A+ ++ + Sbjct: 1970 LGGIPVGVIAVETRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAIKDFNREK 2029 Query: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVI--LRKAYGGAYLAMG 418 +P++ F + G+ G+ +++ GA ++ + P++ I +R+ GG+++ + Sbjct: 2030 LPLMIFANWRGFSGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIRPMRELRGGSWVVID 2089 Query: 419 SK-HLGADFVFAWPTAEIAVMGPEGAANIIFRKE 451 + + ++A + V+ PEG I FRKE Sbjct: 2090 ATINPLCIEMYADKESRGGVLEPEGTVEIKFRKE 2123 >gi|4501855 acetyl-Coenzyme A carboxylase beta [Homo sapiens] >gi|2493312|sp|O00763|COA2_HUMAN ACETYL-COA CARBOXYLASE 2 (ACC-BETA) [INCLUDES: BIOTIN CARBOXYLASE ] >gi|2138330|gb|AAB58382.1| (U89344) acetyl-CoA carboxylase [Homo sapiens] Length = 2483 Score = 74.5 bits (180), Expect = 3e-12 Identities = 89/394 (22%), Positives = 165/394 (41%), Gaps = 39/394 (9%) Query: 86 RLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDSLKGY 145 + +++ QD+T + SL +H I+ E G + D G GV++L+G Sbjct: 1885 KYLYLTPQDYTRIS-SLNSVHCKHIE-------EGGESRYMITDIIGKDDGLGVENLRGS 1936 Query: 146 GEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFMFITGPQVVKAVT 205 G I +++ + I+ + G Y +G ++ V+N + + +TG + V Sbjct: 1937 GMIAGESSLAYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVEN--SHIILTGASALNKVL 1994 Query: 206 GVDV--TPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSNNMEKPPRVKPKD 263 G +V + QLGG + +G +H+ D E + I LSY+P +N P + P D Sbjct: 1995 GREVYTSNNQLGGVQI-MHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTD 2053 Query: 264 EPFRRTPELYDIVPDDPN--KAYDVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIGFGR 321 R L P DP A + + F E+ +A V G R Sbjct: 2054 PIDREIEFLPSRAPYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRAR 2113 Query: 322 INGQTVGIVA-----------NNPIHLAGVLDI----------DSSDKIARFVRFCDAFN 360 + G VG++A +P +L I DS+ K A+ ++ + Sbjct: 2114 LGGIPVGVIAVETRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAIKDFNREK 2173 Query: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVI--LRKAYGGAYLAMG 418 +P++ F + G+ G+ +++ GA ++ + P++ I +R+ GG+++ + Sbjct: 2174 LPLMIFANWRGFSGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIRPMRELRGGSWVVID 2233 Query: 419 SK-HLGADFVFAWPTAEIAVMGPEGAANIIFRKE 451 + + ++A + V+ PEG I FRKE Sbjct: 2234 ATINPLCIEMYADKESRGGVLEPEGTVEIKFRKE 2267 >pir||A75422 acetyl-CoA carboxylase carboxyl transferase, beta subunit - Deinococcus radiodurans (strain R1) >gi|6458959|gb|AAF10788.1|AE001970_3 (AE001970) acetyl-CoA carboxylase carboxyl transferase, beta subunit [Deinococcus radiodurans] Length = 284 Score = 74.1 bits (179), Expect = 3e-12 Identities = 57/183 (31%), Positives = 85/183 (46%), Gaps = 16/183 (8%) Query: 34 KLTARERIELLLDPGSFVEIGMFVKHRATEFGMDKRDLPA------------DGVITGYG 81 +L+A R+E+L DPGSF ++ V D P D ++TG Sbjct: 54 RLSAERRVEVLADPGSFRQLSGQVHPVDPLHFTDTEPYPERLRRAQAKTGRPDAILTGTA 113 Query: 82 TINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDS 141 T++G V + DF GGS+G + +I R E A E+ P++ + SGGAR+QE S Sbjct: 114 TLHGLPVTLAVMDFAFSGGSMGSVVGEEIARAAEYAAESRTPLLLVAASGGARMQESALS 173 Query: 142 LKGYGEIFKMNTILSG-VVPQITAIMGPCAGGAVYSPA-IGDFILMVDNPSTFMFITGPQ 199 L + LSG VP ++ + P GG S A I D I + P + GP+ Sbjct: 174 LMQMAKTTVALEALSGRGVPYLSLLTDPTTGGVTASFATIADVI--IAEPGALIGFAGPR 231 Query: 200 VVK 202 V++ Sbjct: 232 VIQ 234 >pir||C53376 hypothetical protein (iaaH 3' region) - Pseudomonas syringae pv. syringae >gi|472562|gb|AAA17680.1| (U04358) ORF3, which has sequence similarity to a number of carboxylase/decarboxylase subunits of CoA-requiring enzymes from prokaryotes and eukaryotes [Pseudomonas syringae] Length = 220 Score = 73.7 bits (178), Expect = 5e-12 Identities = 49/192 (25%), Positives = 85/192 (43%), Gaps = 15/192 (7%) Query: 316 VIGFGRING---------QTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTF 366 + G G I+G Q +VANN H GV+ ++ K+ + ++PI+ Sbjct: 29 ICGAGTIHGFSRDGQPARQVFAVVANNSAHGGGVMYKRTARKMIHVIGLAGKMSLPILFI 88 Query: 367 VDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADF 426 D+PG + G + E GI A + A+ V + ++ RKAY G AM Sbjct: 89 ADIPGIMIGEEAERDGIFAAVADLFRAHTRCKVKKLLLVARKAYTGGVYAMSGPGFEPVA 148 Query: 427 VFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYID 486 V A+P A I G + + ++I K+ + + ++ + E+ +P + +G I Sbjct: 149 VLAYPDANI------GVFSTLTMEKIIKSSSMTDAQRAVVSALDEEIRSPLLLKDKGLIT 202 Query: 487 DVIDPAETRAKI 498 DVI +TR + Sbjct: 203 DVISVRDTRQAV 214 >sp|P48937|ACCD_BRANA ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (ACCASE BETA CHAIN) >gi|2144155|pir||S66564 acetyl CoA carboxylase type II beta-carboxyltransferase chain - rape chloroplast >gi|1069998|emb|CAA90747.1| (Z50868) acetyl CoA carboxylase carboxyltransferase (beta subunit) [Brassica napus] >gi|1589046|prf||2210244G Ac-CoA carboxylase:SUBUNIT=beta [Brassica napus] Length = 489 Score = 73.7 bits (178), Expect = 5e-12 Identities = 62/188 (32%), Positives = 96/188 (50%), Gaps = 24/188 (12%) Query: 34 KLTARERIELLLDPGSF--VEIGMF----VKHRATEFGMDKRDLPA-------DGVITGY 80 K+T+ ERIEL +DPGS+ ++ M +K + E KR A D + TG Sbjct: 253 KMTSSERIELSIDPGSWNGMDEDMVSADPIKFHSREEPYKKRIASAQKKTGLTDAIQTGT 312 Query: 81 GTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVD 140 G +NG V + DF MGGS+G + KI R++E A P+I + SGGAR+QEG Sbjct: 313 GQLNGIPVALGVMDFQFMGGSMGSVVGDKITRLIEYATNQCLPLILVCSSGGARMQEGSL 372 Query: 141 SLKGYGEIFKMNTIL-----SGVVPQITAIMGPCAGGAVYS-PAIGDFILMVDNPSTFMF 194 SL ++ K++++L S + I+ + P GG S +GD I + P ++ Sbjct: 373 SLM---QMAKISSVLCDYQSSKKLFYISILTSPTTGGVTASLGMLGDII--IAEPYAYIA 427 Query: 195 ITGPQVVK 202 G +V++ Sbjct: 428 FAGKRVIE 435 >pir||G81429 acetyl-CoA carboxylase (EC 6.4.1.2) carboxyltransferase beta chain Cj0127c [similarity] - Campylobacter jejuni (strain NCTC 11168) >gi|6967621|emb|CAB72611.1| (AL139074) acetyl-coenzyme A carboxylase carboxyl transferase subunit beta [Campylobacter jejuni] Length = 280 Score = 73.4 bits (177), Expect = 6e-12 Identities = 58/190 (30%), Positives = 94/190 (48%), Gaps = 16/190 (8%) Query: 34 KLTARERIELLLDPGSFVEIGM---------FVKHRATEFGMDKRDLPA---DGVITGYG 81 +++A ERI+LL D GSF+E FV ++ + + + + VI+G Sbjct: 54 RISADERIKLLSDEGSFIEYDANLEAIDPLKFVDSKSYKKRLSEGESKTGRKSSVISGEC 113 Query: 82 TINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDS 141 ING + DF+ MGGSLG + KI R ++ A+ + ++ ++ SGGAR+QE S Sbjct: 114 EINGLKTQLVVFDFSFMGGSLGSVEGEKIVRAIQRAITSKTSLVIVSASGGARMQESTYS 173 Query: 142 LKGYGEIFKMNTILS-GVVPQITAIMGPCAGGAVYSPA-IGDFILMVDNPSTFMFITGPQ 199 L + +LS +P I+ + P GG S A +GD L++ P + G + Sbjct: 174 LMQMSKTSAALKLLSKEKLPYISILTDPTMGGVSASFAWLGD--LIIAEPEALVGFAGAR 231 Query: 200 VVKAVTGVDV 209 V+K G D+ Sbjct: 232 VIKQTIGADL 241 >gi|11497537 acetyl-coA carboxylase beta subunit [Spinacia oleracea] >gi|7636118|emb|CAB88738.1| (AJ400848) acetyl-coA carboxylase beta subunit [Spinacia oleracea] Length = 522 Score = 72.6 bits (175), Expect = 1e-11 Identities = 57/188 (30%), Positives = 95/188 (50%), Gaps = 24/188 (12%) Query: 34 KLTARERIELLLDPG----------SFVEIGMFVKHRATEFGMDKRDLPA---DGVITGY 80 K+++ +RIELL+DPG S IG + A + +D + + V TG Sbjct: 285 KISSSDRIELLIDPGTWNPMDDDMVSMDPIGFHSEEEAYKDRIDSYQIKTGLTEAVQTGI 344 Query: 81 GTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVD 140 G +NG V + DF MGGS+G + KI R++E A P+I + SGGAR+QEG Sbjct: 345 GQLNGIPVAIGVMDFQFMGGSMGSVVGEKITRLIEYASNKFIPLIIVCASGGARMQEGSL 404 Query: 141 SLKGYGEIFKMNTIL-----SGVVPQITAIMGPCAGGAVYS-PAIGDFILMVDNPSTFMF 194 SL ++ K++++L + + ++ + P GG S +GD I + P+ ++ Sbjct: 405 SLM---QMAKISSVLYDYQSNKKLFYVSILTSPTTGGVTASFGMLGDII--IAEPNAYIA 459 Query: 195 ITGPQVVK 202 G +V++ Sbjct: 460 FAGKRVIE 467 >pir||T07012 acetyl-CoA carboxylase (EC 6.4.1.2) - potato chloroplast >gi|3243216|gb|AAC23997.1| (AF069288) acetyl-coenzyme A carboxylase carboxyl transferase [Solanum tuberosum] Length = 507 Score = 71.8 bits (173), Expect = 2e-11 Identities = 57/185 (30%), Positives = 91/185 (48%), Gaps = 18/185 (9%) Query: 34 KLTARERIELLLDPGSF-------VEIGMFVKHRATEFGMDKRDLP------ADGVITGY 80 K+++ +RIELL+DPG++ V + H E D+ D + V TG Sbjct: 269 KMSSSDRIELLIDPGTWDPMDEDMVSLDPIEFHSEEEPYKDRIDSYQRKTGLTEAVQTGI 328 Query: 81 GTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVD 140 G +NG V + DF MGGS+G + KI R++E A P+I + SGGAR+QEG Sbjct: 329 GQLNGIPVAIGVMDFQFMGGSMGSVVGEKITRLIEHAANQNLPLIIVCASGGARMQEGSL 388 Query: 141 SLKGYGEIFK--MNTILSGVVPQITAIMGPCAGGAVYS-PAIGDFILMVDNPSTFMFITG 197 SL +I + L+ + ++ + P GG S +GD I + P+ ++ G Sbjct: 389 SLMQMAKISSALYDYQLNKKLFYVSILTSPTTGGVTASFGMLGDII--IAEPNAYIAFAG 446 Query: 198 PQVVK 202 +V++ Sbjct: 447 KRVIE 451 >gi|11465966 acetyl-CoA carboxylase beta subunit [Nicotiana tabacum] >gi|141631|sp|P12219|ACCD_TOBAC ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (ACCASE BETA CHAIN) >gi|82218|pir||A05196 hypothetical protein 512 - common tobacco chloroplast >gi|11842|emb|CAA77362.1| (Z00044) acetyl-CoA carboxylase beta subunit [Nicotiana tabacum] >gi|225210|prf||1211235AQ ORF 512 [Nicotiana tabacum] Length = 512 Score = 71.0 bits (171), Expect = 3e-11 Identities = 57/185 (30%), Positives = 91/185 (48%), Gaps = 18/185 (9%) Query: 34 KLTARERIELLLDPGSF-------VEIGMFVKHRATEFGMDKRDLP------ADGVITGY 80 K+++ +RIELL+DPG++ V + H E D+ D + V TG Sbjct: 274 KMSSSDRIELLIDPGTWDPMDEDMVSLDPIEFHSEEEPYKDRIDSYQRKTGLTEAVQTGI 333 Query: 81 GTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVD 140 G +NG V + DF MGGS+G + KI R++E A P+I + SGGAR+QEG Sbjct: 334 GQLNGIPVAIGVMDFQFMGGSMGSVVGEKITRLIEYAANQILPLIIVCASGGARMQEGSL 393 Query: 141 SLKGYGEIFK--MNTILSGVVPQITAIMGPCAGGAVYS-PAIGDFILMVDNPSTFMFITG 197 SL +I + L+ + ++ + P GG S +GD I + P+ ++ G Sbjct: 394 SLMQMAKISSALYDYQLNKKLFYVSILTSPTTGGVTASFGMLGDII--IAEPNAYIAFAG 451 Query: 198 PQVVK 202 +V++ Sbjct: 452 KRVIE 456 >gb|AAA23965.1| (M68935) acetyl-CoA carboxylase beta subunit [Escherichia coli] Length = 304 Score = 71.0 bits (171), Expect = 3e-11 Identities = 54/165 (32%), Positives = 81/165 (48%), Gaps = 20/165 (12%) Query: 34 KLTARERIELLLDPGSFVEIGMFV------------KHRATEFGMDKRDLPADGVITGYG 81 ++TAR R+ LLD GS VE+G V K++ K D ++ G Sbjct: 54 RMTARNRLHSLLDEGSLVELGSSVEPKDVLKFRDSKKYKDRLASAQKETGEKDALVVMKG 113 Query: 82 TINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDS 141 T+ G V A +F MGGS+G + + R +E ALE P+I + SGGAR+QE + S Sbjct: 114 TLYGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLICFSASGGARMQEALMS 173 Query: 142 LKGYGEIFKMNTILSGV----VPQITAIMGPCAGGAVYSPA-IGD 181 L ++ K + L+ + +P I+ + P GG S A +GD Sbjct: 174 LM---QMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGD 215 >gi|11466711 ORF316 [Marchantia polymorpha] >gi|141629|sp|P12217|ACCD_MARPO ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (ACCASE BETA CHAIN) >gi|81350|pir||A05043 finger protein zfpA - liverwort (Marchantia polymorpha) chloroplast >gi|11681|emb|CAA28093.1| (X04465) ORF316 [Marchantia polymorpha] Length = 316 Score = 70.6 bits (170), Expect = 4e-11 Identities = 57/187 (30%), Positives = 91/187 (48%), Gaps = 23/187 (12%) Query: 34 KLTARERIELLLDPGSFVEIGMFVKHRATEFGMD------------KRDLPADGVITGYG 81 ++++ ERIELL+D G++ + + R D KR D + TG G Sbjct: 78 QMSSTERIELLIDRGTWYPMDEDMTARDVLKFSDEDSYKNRIAFYQKRTGLTDAIQTGIG 137 Query: 82 TINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDS 141 +NG + + DF MGGS+G + KI R++E A A P+I + SGGAR+QEG S Sbjct: 138 QLNGIPIALGVMDFQFMGGSMGSVVGEKITRLIEYATRASMPLIIVCSSGGARMQEGTLS 197 Query: 142 LKGYGEIFKMNTILSGVVPQ-----ITAIMGPCAGGAVYS-PAIGDFILMVDNPSTFMFI 195 L ++ K++++L Q I + P GG S +GD I + P ++ Sbjct: 198 LM---QMAKISSVLQIHQAQKRLLYIAILTYPTTGGVTASFGMLGDII--IAEPKAYIAF 252 Query: 196 TGPQVVK 202 G +V++ Sbjct: 253 AGKRVIE 259 >pir||I41212 folC expression protein - Escherichia coli >gi|146008|gb|AAA23801.1| (J02808) protein required for folC expression [Escherichia coli] >gi|146019|gb|AAA23807.1| (M32445) protein of unknown function [Escherichia coli] Length = 304 Score = 70.2 bits (169), Expect = 5e-11 Identities = 56/177 (31%), Positives = 85/177 (47%), Gaps = 22/177 (12%) Query: 34 KLTARERIELLLDPGSFVEIGMFV------------KHRATEFGMDKRDLPADGVITGYG 81 ++TAR R+ LLD GS VE+G + K++ K D ++ G Sbjct: 54 RMTARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKETGEKDALVVMKG 113 Query: 82 TINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDS 141 T+ G V A +F MGGS+G + + R +E ALE P+I + SGGAR+QE + S Sbjct: 114 TLYGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLICFSASGGARMQEALMS 173 Query: 142 LKGYGEIFKMNTILSGV----VPQITAIMGPCAGGAVYSPA-IGDFILMVDNPSTFM 193 L ++ K + L+ + +P I+ + P GG S A +GD L + P M Sbjct: 174 LM---QMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGD--LNIAEPKALM 225 >gi|7525042 carboxytransferase beta subunit [Arabidopsis thaliana] >gi|6685210|sp|P56765|ACCD_ARATH ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (ACCASE BETA CHAIN) >gi|5881703|dbj|BAA84394.1| (AP000423) carboxytransferase beta subunit [Arabidopsis thaliana] >gi|7021219|gb|AAF35256.1|AF056971_1 (AF056971) carboxyltransferase beta subunit [Arabidopsis thaliana] Length = 488 Score = 69.5 bits (167), Expect = 9e-11 Identities = 59/188 (31%), Positives = 92/188 (48%), Gaps = 24/188 (12%) Query: 34 KLTARERIELLLDPGSF-------VEIGMFVKHRATEFGMDKRDLP------ADGVITGY 80 K+++ ERIEL +DPG++ V H E ++ D D V TG Sbjct: 255 KMSSSERIELSIDPGTWNPMDEDMVSADPIKFHSKEEPYKNRIDSAQKTTGLTDAVQTGT 314 Query: 81 GTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVD 140 G +NG V + DF MGGS+G + KI R++E A P+I + SGGAR+QEG Sbjct: 315 GQLNGIPVALGVMDFRFMGGSMGSVVGEKITRLIEYATNQCLPLILVCSSGGARMQEGSL 374 Query: 141 SLKGYGEIFKMNTIL-----SGVVPQITAIMGPCAGGAVYS-PAIGDFILMVDNPSTFMF 194 SL ++ K++++L S + I+ + P GG S +GD I + P ++ Sbjct: 375 SLM---QMAKISSVLCDYQSSKKLFYISILTSPTTGGVTASFGMLGDII--IAEPYAYIA 429 Query: 195 ITGPQVVK 202 G +V++ Sbjct: 430 FAGKRVIE 437 >pir||T32413 probable acetyl-CoA carboxylase (EC 6.4.1.2) W09B6.1 [similarity] - Caenorhabditis elegans >gi|9803022|gb|AAG00029.1| (AF025469) Contains similarity to Pfam domain: PF00364 (biotin_req_enzy), Score=14.2, E-value=0.00077, N=1 [Caenorhabditis elegans] Length = 2054 Score = 69.5 bits (167), Expect = 9e-11 Identities = 92/397 (23%), Positives = 166/397 (41%), Gaps = 60/397 (15%) Query: 138 GVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFMFITG 197 GV++L+G G I VP + G G Y+ + I V + + + +TG Sbjct: 1548 GVENLQGSGLIAGETARAYAEVPTYCYVTGRSVGIGAYTARLAHRI--VQHKQSHLILTG 1605 Query: 198 PQVVKAVTGVDV--TPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSNNMEK 255 + + + G V + QLGG V ++G H + +D E I + R +S+LP+ E Sbjct: 1606 YEALNTLLGKKVYTSNNQLGGPEVMF-RNGVTHAVVDNDLEGIAKVIRWMSFLPTPTEEF 1664 Query: 256 PPRVKPKDEPFRRTPELYDIVPDDPNK-AYDVRQVIYAIVDRDENGNPD---FLELQPYF 311 P K D+ R ++P D + YDVR +I + ++ G D F E+ + Sbjct: 1665 PFFSKHGDDCSARDV----VIPSDSEQNTYDVRDLIDSKNLSNQTGICDTMSFDEICGDW 1720 Query: 312 APNAVIGFGRINGQTVGIVANNPIHLAGVLDID---------------------SSDKIA 350 A + V G R+ G +G+V++ + + ++ D S+ K A Sbjct: 1721 AKSIVAGRARLCGIPIGVVSSEFRNFSTIVPADPAIDGSQVQNTQRAGQVWYPDSAFKTA 1780 Query: 351 RFVRFCDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVI--LRK 408 + + N+P++ + G+ G +++ GA+++ A A P++ I + Sbjct: 1781 EAINDLNKENLPLMIIASLRGFSGGQKDMYDMVLKFGAQIVDALAVYNRPVIVYIPEAGE 1840 Query: 409 AYGGAYLAMGSK------HLGADFVFAWPTAEIAVMGPEGAANIIFRK----EIAKAENP 458 GGA+ + SK HL AD + ++ P I FRK E+ K +P Sbjct: 1841 LRGGAWAVLDSKIRPEFIHLVAD-----EKSRGGILEPNAVVGIKFRKPMMMEMMKRSDP 1895 Query: 459 ---------EEFRKQKIQEYREKFANPYVAASRGYID 486 E +++++E E+ + Y AS + D Sbjct: 1896 TYSKLSSSTEPEAREQLEERYEELSKTYRNASVEFAD 1932 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.320 0.140 0.407 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 202250123 Number of Sequences: 2977 Number of extensions: 9157225 Number of successful extensions: 26128 Number of sequences better than 1.0e-10: 85 Number of HSP's better than 0.0 without gapping: 60 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 25708 Number of HSP's gapped (non-prelim): 99 length of query: 522 length of database: 189,106,746 effective HSP length: 56 effective length of query: 466 effective length of database: 155,591,474 effective search space: 72505626884 effective search space used: 72505626884 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.8 bits) S2: 167 (69.5 bits)