BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1769 (mmdA) DE:methylmalonyl-CoA decarboxylase, subunit
alpha (mmdA)
         (522 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||H75135 methylmalonyl-coa decarboxylase, chain A lpha (mmda)...  1051  0.0
pir||D71074 probable methylmalonyl-CoA decarboxylase alpha chain...  1023  0.0
gi|11499799 methylmalonyl-CoA decarboxylase, subunit alpha (mmdA...   773  0.0
pir||C72344 propionyl-CoA carboxylase, beta subunit - Thermotoga...   698  0.0
dbj|BAB06676.1| (AP001517) methylmalonyl-CoA decarboxylase alpha...   651  0.0
pir||T44982 methylmalonyl-CoA decarboxylase (EC 4.1.1.41) alpha ...   639  0.0
gb|AAK42602.1| Propionyl-CoA carboxylase beta subunit (ppcB) [Su...   624  e-178
gb|AAG19817.1| (AE005066) methylmalonyl-CoA decarboxylase, subun...   621  e-177
pir||T43828 propionyl-CoA carboxylase (EC 6.4.1.3) [validated] -...   616  e-175
pir||T44289 probable methylmalonyl-CoA decarboxylase (EC 4.1.1.4...   612  e-174
pir||H75410 probable propionyl-CoA carboxylase, alpha subunit - ...   609  e-173
pir||A49094 methylmalonyl-CoA decarboxylase (EC 4.1.1.41) alpha ...   607  e-173
pir||D71667 propionyl-COA carboxylase beta chain precursor (pccB...   600  e-170
sp|P53003|PCCB_SACER PROPIONYL-COA CARBOXYLASE BETA CHAIN (PCCAS...   596  e-169
pir||T42208 propionyl-CoA carboxylase complex B chain - Streptom...   596  e-169
pir||T29065 probable methylmalonyl-CoA decarboxylase (EC 4.1.1.4...   583  e-165
sp|P79384|PCCB_PIG PROPIONYL-COA CARBOXYLASE BETA CHAIN, MITOCHO...   562  e-159
pir||T45009 propionyl-CoA carboxylase (EC 6.4.1.3) beta chain pr...   558  e-158
pir||T16428 propionyl-CoA carboxylase (EC 6.4.1.3) beta chain F5...   557  e-157
gi|4557044 propionyl Coenzyme A carboxylase, beta polypeptide [H...   555  e-157
gb|AAD13544.1| (AF080235) decarboxylase homolog [Streptomyces cy...   554  e-157
pir||A53020 propionyl-CoA carboxylase (EC 6.4.1.3) beta chain pr...   553  e-156
pir||A70980 probable accD5 protein - Mycobacterium tuberculosis ...   552  e-156
sp|P54541|PCCB_BACSU PUTATIVE PROPIONYL-COA CARBOXYLASE BETA CHA...   551  e-156
gi|8393913 propionyl Coenzyme A carboxylase, beta polypeptide [R...   550  e-155
sp|P53002|PCCB_MYCLE PROBABLE PROPIONYL-COA CARBOXYLASE BETA CHA...   550  e-155
dbj|BAA33850.1| (AB018531) dtsR2 [Corynebacterium glutamicum]         538  e-152
pir||JC4991 detergent sensitivity rescuer - Corynebacterium glut...   501  e-141
pir||A48665 methylmalonyl-CoA carboxyltransferase (EC 2.1.3.1) 1...   450  e-125
pir||C70887 probable Propionyl-CoA carboxylase - Mycobacterium t...   439  e-122
sp|Q10506|PCCB_MYCTU PROBABLE PROPIONYL-COA CARBOXYLASE BETA CHA...   351  1e-95
pir||T44709 acetyl/propionyl CoA carboxylase [imported] - Mycoba...   344  2e-93
pir||B69893 propionyl-CoA carboxylase homolog yngE - Bacillus su...   343  3e-93
dbj|BAB04855.1| (AP001511) propionyl-CoA carboxylase [Bacillus h...   341  1e-92
gb|AAG19127.1| (AE005010) propionyl-CoA carboxylase homolog; Yng...   332  8e-90
gb|AAF32341.1|AF218939_9 (AF218939) b-propionyl-CoA carboxylase ...   329  4e-89
sp|Q06101|PCCB_RHOER PROPIONYL-COA CARBOXYLASE BETA CHAIN (PCCAS...   327  2e-88
sp|P34385|YLP5_CAEEL HYPOTHETICAL 66.5 KD PROTEIN F02A9.5 IN CHR...   287  2e-76
emb|CAB87213.1| (AL163641) acetyl/propionyl CoA carboxylase, bet...   283  4e-75
gb|AAF35258.1|AF059510_1 (AF059510) 3-methylcrotonyl-CoA carboxy...   277  2e-73
gb|AAG17227.1|AF217984_1 (AF217984) unknown [Homo sapiens]            277  2e-73
pir||F70550 probable accD1 protein - Mycobacterium tuberculosis ...   276  4e-73
gi|11545863 non-biotin containing subunit of 3-methylcrotonyl-Co...   270  4e-71
gb|AAC38045.1| (U94697) propionyl-CoA carboxylase beta chain hom...   269  5e-71
gb|AAF57388.1| (AE003789) CG3267 gene product [Drosophila melano...   266  3e-70
pir||F75382 probable propionyl-CoA carboxylase, beta subunit - D...   264  2e-69
emb|CAA68941.1| (Y07660) B subunit of propionyl-CoA carboxylase ...   259  4e-68
pir||C83395 probable acyl-CoA carboxyltransferase beta chain PA2...   255  8e-67
pir||T05433 hypothetical protein F28A23.210 - Arabidopsis thalia...   253  3e-66
pir||D70719 probable propionyl-CoA carboxylase - Mycobacterium t...   238  9e-62
emb|CAB95891.1| (AL359988) putative acetyl/propionyl CoA carboxy...   238  2e-61
dbj|BAB16296.1| (AB039884) acetyl-CoA carboxylase carboxyltransf...   238  2e-61
pir||C83284 probable biotin-dependent carboxylase PA2888 [import...   235  1e-60
pir||B83471 probable pyruvate carboxylase PA1400 [imported] - Ps...   224  2e-57
pir||C75585 carboxylase - Deinococcus radiodurans (strain R1) >g...   215  1e-54
pir||T45098 probable propionyl-coA carboxylase beta chain [impor...   197  3e-49
gb|AAC69174.1| (AF030576) methylmalonyl-CoA decarboxylase alpha ...   194  2e-48
gb|AAA60036.1| (M13573) propionyl-CoA carboxylase beta chain (EC...   185  1e-45
emb|CAA74219.1| (Y13917) yngE [Bacillus subtilis]                     169  9e-41
sp|Q06700|GCDA_ACIFE GLUTACONYL-COA DECARBOXYLASE A SUBUNIT (CAR...   128  2e-28
emb|CAC00930.1| (AL390935) probable propionyl-coa carboxylase be...   108  1e-22
emb|CAA19885.1| (AL031032) putative protein (fragment) [Arabidop...    94  4e-18
pir||H81687 acetyl-coenzyme A carboxylase carboxyl transferase, ...    83  9e-15
gb|AAB97629.1| (AF121266) malonate decarboxylase beta subunit [A...    80  8e-14
pir||C72124 acetyl-coenzyme A carboxylase carboxyl transferase, ...    80  8e-14
emb|CAC00894.1| (AL390935) probable propionyl-coa carboxylase be...    79  1e-13
sp|P08193|ACCD_ECOLI ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRAN...    78  3e-13
pir||B71534 probable accoa carboxylase/transferase beta - Chlamy...    77  5e-13
pir||E71875 acetyl-coenzyme A carboxylase chain B - Helicobacter...    76  9e-13
pir||F64638 acetyl-CoA carboxylase beta subunit - Helicobacter p...    76  1e-12
gb|AAG24832.1| (AF294436) acetyl-CoA carboxylase beta subunit [B...    76  1e-12
pir||S41121 acetyl-CoA carboxylase (EC 6.4.1.2) - human >gi|4523...    75  3e-12
gi|4501855 acetyl-Coenzyme A carboxylase beta [Homo sapiens] >gi...    75  3e-12
pir||A75422 acetyl-CoA carboxylase carboxyl transferase, beta su...    74  3e-12
pir||C53376 hypothetical protein (iaaH 3' region) - Pseudomonas ...    74  5e-12
sp|P48937|ACCD_BRANA ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRAN...    74  5e-12
pir||G81429 acetyl-CoA carboxylase (EC 6.4.1.2) carboxyltransfer...    73  6e-12
gi|11497537 acetyl-coA carboxylase beta subunit [Spinacia olerac...    73  1e-11
pir||T07012 acetyl-CoA carboxylase (EC 6.4.1.2) - potato chlorop...    72  2e-11
gi|11465966 acetyl-CoA carboxylase beta subunit [Nicotiana tabac...    71  3e-11
gb|AAA23965.1| (M68935) acetyl-CoA carboxylase beta subunit [Esc...    71  3e-11
gi|11466711 ORF316 [Marchantia polymorpha] >gi|141629|sp|P12217|...    71  4e-11
pir||I41212 folC expression protein - Escherichia coli >gi|14600...    70  5e-11
gi|7525042 carboxytransferase beta subunit [Arabidopsis thaliana...    69  9e-11
pir||T32413 probable acetyl-CoA carboxylase (EC 6.4.1.2) W09B6.1...    69  9e-11

>pir||H75135 methylmalonyl-coa decarboxylase, chain A lpha (mmda) PAB1769 -
           Pyrococcus abyssi (strain Orsay)
           >gi|5458312|emb|CAB49801.1| (AJ248285) methylmalonyl-CoA
           decarboxylase, subunit a lpha (mmdA) [Pyrococcus abyssi]
           Length = 522
           
 Score = 1051 bits (2688), Expect = 0.0
 Identities = 522/522 (100%), Positives = 522/522 (100%)

Query: 1   MGMMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHR 60
           MGMMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHR
Sbjct: 1   MGMMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHR 60

Query: 61  ATEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA 120
           ATEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA
Sbjct: 61  ATEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA 120

Query: 121 GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG 180
           GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG
Sbjct: 121 GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG 180

Query: 181 DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL 240
           DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL
Sbjct: 181 DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL 240

Query: 241 IKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENG 300
           IKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENG
Sbjct: 241 IKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENG 300

Query: 301 NPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN 360
           NPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN
Sbjct: 301 NPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN 360

Query: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSK 420
           IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSK
Sbjct: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSK 420

Query: 421 HLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAA 480
           HLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAA
Sbjct: 421 HLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAA 480

Query: 481 SRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           SRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL
Sbjct: 481 SRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522


>pir||D71074 probable methylmalonyl-CoA decarboxylase alpha chain - Pyrococcus
           horikoshii >gi|3257707|dbj|BAA30390.1| (AP000005) 522aa
           long hypothetical methylmalonyl-CoA decarboxylase alpha
           chain [Pyrococcus horikoshii]
           Length = 522
           
 Score = 1023 bits (2617), Expect = 0.0
 Identities = 503/522 (96%), Positives = 518/522 (98%)

Query: 1   MGMMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHR 60
           MGM+EKVE+L++R+KKILQMGGEEAIKKQH+KGKLTARER+ELLLDPGSFVEIGMFVKHR
Sbjct: 1   MGMIEKVEELHERKKKILQMGGEEAIKKQHEKGKLTARERLELLLDPGSFVEIGMFVKHR 60

Query: 61  ATEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA 120
           ATEFGMDKR+LPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA
Sbjct: 61  ATEFGMDKRELPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA 120

Query: 121 GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG 180
           GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG
Sbjct: 121 GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG 180

Query: 181 DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL 240
           DFILMVDNPSTFMFITGPQVVKAVTGV+VTPVQLGGA+VHAQ+SGQAHLIGKSDEEVI L
Sbjct: 181 DFILMVDNPSTFMFITGPQVVKAVTGVEVTPVQLGGAMVHAQRSGQAHLIGKSDEEVIML 240

Query: 241 IKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENG 300
           IK+LLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNK YDVRQVIY IVDRDENG
Sbjct: 241 IKKLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKGYDVRQVIYTIVDRDENG 300

Query: 301 NPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN 360
           NPDFLELQPYFAPNAVIGFGRINGQ VGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN
Sbjct: 301 NPDFLELQPYFAPNAVIGFGRINGQPVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN 360

Query: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSK 420
           IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVT+ILRKAYGGAYLAMGSK
Sbjct: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTIILRKAYGGAYLAMGSK 420

Query: 421 HLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAA 480
           HLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFR+QKIQEYREKFANPYVAA
Sbjct: 421 HLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRRQKIQEYREKFANPYVAA 480

Query: 481 SRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           +RGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL
Sbjct: 481 ARGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522


>gi|11499799 methylmalonyl-CoA decarboxylase, subunit alpha (mmdA)
           [Archaeoglobus fulgidus] >gi|7438114|pir||A69527
           methylmalonyl-CoA decarboxylase, subunit alpha (mmdA)
           homolog - Archaeoglobus fulgidus
           >gi|2648306|gb|AAB89035.1| (AE000952) methylmalonyl-CoA
           decarboxylase, subunit alpha (mmdA) [Archaeoglobus
           fulgidus]
           Length = 516
           
 Score =  773 bits (1974), Expect = 0.0
 Identities = 370/518 (71%), Positives = 437/518 (83%), Gaps = 5/518 (0%)

Query: 5   EKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEF 64
           E VE+LY +++KI QMGG+E I++QH++GKLTARERIELLLDPGSFVEI  FV+ R T+F
Sbjct: 4   ELVEELYGKKEKIRQMGGKERIERQHEQGKLTARERIELLLDPGSFVEINPFVEKRNTDF 63

Query: 65  GMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPV 124
           G+DK DLPADGV+TGYGT++GR V V+AQDFTVMGGSLGEMH  KI  I++ A++ G PV
Sbjct: 64  GLDKMDLPADGVVTGYGTVDGRPVAVFAQDFTVMGGSLGEMHGFKIAYILDFAMKLGIPV 123

Query: 125 IGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFIL 184
           +GLNDSGGARIQEGVD+LKGYG+IF  NT+ SGV+PQI+ IMGPCAGGAVYSPAIGDFI+
Sbjct: 124 VGLNDSGGARIQEGVDALKGYGDIFYRNTLASGVIPQISVIMGPCAGGAVYSPAIGDFIV 183

Query: 185 MVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRL 244
           M  NP+ +MFITGPQV+K VTG +V+   LGG   HA KSG  HL+ + D + + L++RL
Sbjct: 184 MTKNPNCYMFITGPQVIKTVTGEEVSAFDLGGWQAHAMKSGNCHLVAEDDRDAMMLVRRL 243

Query: 245 LSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDF 304
           LSYLP NNME PP VK  D+P R TPE+YD++PDDP K YDVR VI A+VD     N + 
Sbjct: 244 LSYLPLNNMEDPPVVKTGDDPVRLTPEIYDVLPDDPQKPYDVRDVITAVVD-----NGEL 298

Query: 305 LELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIV 364
           LE+ PY+APNAV+GF RI+G++VGIVANNP H AG LD+DSSDKIARFVRFCDAFNIPI+
Sbjct: 299 LEIHPYYAPNAVVGFARIDGKSVGIVANNPRHFAGCLDVDSSDKIARFVRFCDAFNIPII 358

Query: 365 TFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGA 424
           TFVDVPGYLPGV QE  GIIRHGAKVLYAY+EATVP+VT+ILRKAYGGAYLAMGSKHLGA
Sbjct: 359 TFVDVPGYLPGVQQEYGGIIRHGAKVLYAYSEATVPLVTIILRKAYGGAYLAMGSKHLGA 418

Query: 425 DFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGY 484
           D V+A+PTAEIAVMGPEGAA I+FRKEI  AE+P+  R++KI+EYREKFANPY AA+RGY
Sbjct: 419 DIVYAYPTAEIAVMGPEGAAEIVFRKEIKAAEDPKAMREEKIREYREKFANPYRAAARGY 478

Query: 485 IDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           IDD+IDP  TR K+V AL  LE+KR KLPPKKHGNIPL
Sbjct: 479 IDDIIDPKYTRVKVVSALRILESKREKLPPKKHGNIPL 516


>pir||C72344 propionyl-CoA carboxylase, beta subunit - Thermotoga maritima
           (strain MSB8) >gi|4981240|gb|AAD35798.1|AE001742_13
           (AE001742) propionyl-CoA carboxylase, beta subunit
           [Thermotoga maritima]
           Length = 515
           
 Score =  698 bits (1781), Expect = 0.0
 Identities = 349/522 (66%), Positives = 413/522 (78%), Gaps = 7/522 (1%)

Query: 1   MGMMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHR 60
           M + +K+E+L +  K+I Q GG E ++KQH  GKLTA ER+ELLLDPG+FVEI  FV+HR
Sbjct: 1   MSLRDKIEELKKIEKEIEQGGGPEKVEKQHRAGKLTAWERLELLLDPGTFVEIDKFVEHR 60

Query: 61  ATEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA 120
            T FG+DK  LP DGVITG G INGR V V++QDFTVMGGSLGEMHA KI ++++LAL+ 
Sbjct: 61  NTYFGLDKVKLPRDGVITGVGEINGRKVAVFSQDFTVMGGSLGEMHAKKIVKLLDLALKM 120

Query: 121 GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG 180
           G PVIG+NDSGGARIQEGVD+L GYGEIF  NT+ SGVVPQIT I GPCAGGAVYSPA+ 
Sbjct: 121 GIPVIGINDSGGARIQEGVDALAGYGEIFLRNTLASGVVPQITVIAGPCAGGAVYSPALT 180

Query: 181 DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL 240
           DFI+MVD  +  MFITGP V+KAVTG +++   LGGA+VH QKSG AH +  +DE+ + L
Sbjct: 181 DFIVMVDQTAR-MFITGPNVIKAVTGEEISQEDLGGAMVHNQKSGNAHFLADNDEKAMSL 239

Query: 241 IKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENG 300
           ++ LLSYLPSNN E+PP V+  D       ++ DI+PD+PNK YDVR VI  +VD  E  
Sbjct: 240 VRTLLSYLPSNNAEEPP-VEDPDTSLETPEDILDILPDNPNKGYDVRDVIKRVVDHGE-- 296

Query: 301 NPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN 360
              F E+QPYFA N VIGF RI G+TVGIVAN P  LAGVLDIDSSDK ARF+RF DAFN
Sbjct: 297 ---FFEVQPYFAKNIVIGFARIQGKTVGIVANQPSVLAGVLDIDSSDKAARFIRFLDAFN 353

Query: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSK 420
           IPI+TFVD PGYLPGV QE  GIIRHGAK+LYAY+EATVP +TVILRKAYGGAY+AMGSK
Sbjct: 354 IPILTFVDTPGYLPGVAQEHGGIIRHGAKLLYAYSEATVPKITVILRKAYGGAYIAMGSK 413

Query: 421 HLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAA 480
           HLGAD V AWP+AEIAVMGPEGAANIIF++EI  + NPEE R++ I+EY+++FANPY+AA
Sbjct: 414 HLGADMVLAWPSAEIAVMGPEGAANIIFKREIEASSNPEETRRKLIEEYKQQFANPYIAA 473

Query: 481 SRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           SRGY+D VIDP ETR  I+ ALE  E K    P KKHGNIPL
Sbjct: 474 SRGYVDMVIDPRETRKYIMRALEVCETKVEYRPKKKHGNIPL 515


>dbj|BAB06676.1| (AP001517) methylmalonyl-CoA decarboxylase alpha subunit [Bacillus
           halodurans]
           Length = 516
           
 Score =  651 bits (1662), Expect = 0.0
 Identities = 325/527 (61%), Positives = 400/527 (75%), Gaps = 16/527 (3%)

Query: 1   MGMMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHR 60
           M M +++ ++  RR K+   GG + I  QHD+GKLTARERI+LLLD G+FVE+  F++HR
Sbjct: 1   MDMFDRIHEMEVRRDKVKLGGGSKRIDAQHDRGKLTARERIDLLLDEGTFVELNPFIEHR 60

Query: 61  ATEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA 120
             +FG    + P +GV+TGYG ++GRLVF++AQDFTV GG+LGEMHA KI ++M+LA E 
Sbjct: 61  GLDFGT--AEAPGEGVVTGYGKVDGRLVFLFAQDFTVFGGALGEMHARKITKVMDLAAEN 118

Query: 121 GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG 180
           GAP++GLNDSGGARIQEGV SL GYGEIF  N+I SGV+PQI+ I+GPCAGGAVYSPAI 
Sbjct: 119 GAPIVGLNDSGGARIQEGVRSLDGYGEIFYRNSIYSGVIPQISVILGPCAGGAVYSPAIT 178

Query: 181 DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL 240
           DF+ MV+  S  MFITGP+V+++VTG  +    LGGA VH+  SG AH    S+E V+  
Sbjct: 179 DFVFMVEKTSQ-MFITGPKVIESVTGAKINSEDLGGAKVHSTISGNAHFTAASEEGVLQQ 237

Query: 241 IKRLLSYLPSNNMEKPPRVK-----PKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVD 295
           ++ LLSYLPS+  EKPP  +     P DE   R  EL DIVP D  K YDVR VI  +VD
Sbjct: 238 VRNLLSYLPSSFEEKPPHQRAKHPVPLDE---RVQELLDIVPVDGTKVYDVRHVIEKVVD 294

Query: 296 RDENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRF 355
            ++     FLE+QP FA N V+GF RING TVGI+ANNP  +AG LDI+SSDK ARF+RF
Sbjct: 295 DEQ-----FLEVQPQFARNIVVGFARINGDTVGIIANNPKMMAGGLDINSSDKCARFIRF 349

Query: 356 CDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYL 415
           CD FNIP++TF DV G++PGV QE  GIIRHGAK+LYAY+EATVP +TVILRKAYGGAY+
Sbjct: 350 CDCFNIPLITFEDVSGFIPGVQQEHGGIIRHGAKILYAYSEATVPKITVILRKAYGGAYV 409

Query: 416 AMGSKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFAN 475
           A+ SK +GAD VFAWP AE+AVMGPEGAANIIF KEI ++ NP+  R+ KI EYRE+FAN
Sbjct: 410 ALNSKAIGADLVFAWPNAELAVMGPEGAANIIFAKEIKESANPDATRQAKISEYRERFAN 469

Query: 476 PYVAASRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           PYVAA+ G IDDVIDP +TR  +V AL  L+NK+  LP KKHGNIPL
Sbjct: 470 PYVAAANGMIDDVIDPRDTRKSLVSALAMLKNKKKTLPKKKHGNIPL 516


>pir||T44982 methylmalonyl-CoA decarboxylase (EC 4.1.1.41) alpha chain
           [validated] - Propionigenium modestum (fragment)
           >gi|2706398|emb|CAA05137.1| (AJ002015) methylmalonyl-CoA
           decarboxylase, alpha-subunit [Propionigenium modestum]
           Length = 512
           
 Score =  639 bits (1630), Expect = 0.0
 Identities = 316/518 (61%), Positives = 397/518 (76%), Gaps = 6/518 (1%)

Query: 5   EKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEF 64
           +K++DL ++++KI   GG + I+KQH  GK+TARER+  L D G+FVE+  FV+HR T F
Sbjct: 1   KKIQDLQKKKEKIALGGGIKRIEKQHASGKMTARERLAYLFDEGTFVEMDAFVQHRCTNF 60

Query: 65  GMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPV 124
           GMDK+DLP++ V+TGYG ++GR+V+ ++QDFTV GG+LGEMHA KI + M++A + GAPV
Sbjct: 61  GMDKQDLPSESVVTGYGMVDGRVVYAFSQDFTVTGGALGEMHAKKICKAMDMAGKVGAPV 120

Query: 125 IGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFIL 184
           +GLNDSGGARIQE VD+L GYG+IF  N+I SGVVPQI+AI+GPCAGGAVYSPA+ DFI 
Sbjct: 121 VGLNDSGGARIQEAVDALSGYGDIFYRNSIYSGVVPQISAILGPCAGGAVYSPALTDFIF 180

Query: 185 MVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRL 244
           MVD  S  MFITGPQV+K VTG +VT  QLGGA+ H   SG A  I + D+  I  I+RL
Sbjct: 181 MVDQTSQ-MFITGPQVIKTVTGEEVTAEQLGGAMTHNSTSGCAQFISQDDKACIDDIRRL 239

Query: 245 LSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDF 304
           +S+LPSNNMEK P    +D+   + PEL  ++PD+PNKAY++  VI  IVD     N D+
Sbjct: 240 ISFLPSNNMEKAPEFGCEDDLNIQFPELDALMPDNPNKAYNMFDVITKIVD-----NGDY 294

Query: 305 LELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIV 364
           +E QP+++ N +  F R+NG++VGI+AN P  +AG LDIDS DK A+F+R CDAFNIP++
Sbjct: 295 MEYQPHYSKNIITCFARVNGKSVGIIANQPQVMAGCLDIDSGDKCAKFIRTCDAFNIPLL 354

Query: 365 TFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGA 424
           T VDVPG+LPGV QE  GIIRHGAK+LYAY+EATVP VT+I RKAYGGAY+AM SK LGA
Sbjct: 355 TIVDVPGFLPGVTQEYGGIIRHGAKILYAYSEATVPKVTLITRKAYGGAYVAMCSKSLGA 414

Query: 425 DFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGY 484
           D V AWPTAEIAVMGP GA NIIFRK+I  A++P    KQK+ EY  +FANPY AA RG 
Sbjct: 415 DVVLAWPTAEIAVMGPAGAVNIIFRKDIKDAKDPAATTKQKLDEYTTEFANPYQAARRGL 474

Query: 485 IDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           +DDVI+P  +R +IV A   LE KR KLP KKHGNIPL
Sbjct: 475 VDDVIEPKTSRQRIVDAFNMLEGKREKLPAKKHGNIPL 512


>gb|AAK42602.1| Propionyl-CoA carboxylase beta subunit (ppcB) [Sulfolobus
           solfataricus]
           Length = 523
           
 Score =  624 bits (1592), Expect = e-178
 Identities = 305/520 (58%), Positives = 381/520 (72%), Gaps = 5/520 (0%)

Query: 3   MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRAT 62
           M + +EDL   ++K+ + GGEE I  QH KGKLTARER+  L D G F EI  F   RAT
Sbjct: 9   MDKLIEDLKILKEKVYKGGGEEKINFQHGKGKLTARERLNQLFDEGKFNEILTFATTRAT 68

Query: 63  EFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGA 122
           EFG+DK     DGVI G+G I+GR VF YAQDFT++GGSLGE HA KI R  ELAL+ GA
Sbjct: 69  EFGLDKNRFYGDGVIAGWGKIDGRQVFAYAQDFTILGGSLGETHANKIVRAYELALKVGA 128

Query: 123 PVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDF 182
           PVIG+NDSGGARIQEG  SL+GYG +FKMN + SGV+PQIT + GP AGGAVYSPA+ DF
Sbjct: 129 PVIGINDSGGARIQEGALSLEGYGAVFKMNVMASGVIPQITIMAGPAAGGAVYSPALTDF 188

Query: 183 ILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIK 242
           ++M+   + +MF+TGP++ K   G +V+   LGGA++HA KSG  H + +++++ I + K
Sbjct: 189 LIMIKGDAYYMFVTGPEITKVSIGEEVSYQDLGGAIIHATKSGVVHFVAENEQDAINITK 248

Query: 243 RLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNP 302
           RLLSYLPSNNME+PP V   D   R       IVP D  K +D+R +IY IVD     N 
Sbjct: 249 RLLSYLPSNNMEEPPYVDTGDPADRAVQSAESIVPTDSVKPFDIRDLIYNIVD-----NS 303

Query: 303 DFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIP 362
           +FLE+   +A N  +GFGRING  VGIVANN  +  G +DID++DK ARF+RFCDAFNIP
Sbjct: 304 EFLEVHKLWAQNITVGFGRINGNVVGIVANNSAYYGGAIDIDAADKAARFIRFCDAFNIP 363

Query: 363 IVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHL 422
           +++ VD PGY+PG DQE +GIIRHGAK+LYA+AEATVP +TVI+R++YGGA++AM  K L
Sbjct: 364 VISLVDTPGYVPGTDQEYKGIIRHGAKMLYAFAEATVPKITVIVRRSYGGAHIAMSIKSL 423

Query: 423 GADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASR 482
           GAD V+AWP+AEIAV GPEGA  I++R+EI  A+NPEE  KQKI EY++ FANPY AA +
Sbjct: 424 GADLVYAWPSAEIAVTGPEGAVRILYRREIQSAQNPEELLKQKITEYKKLFANPYWAAEK 483

Query: 483 GYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           G IDDVI+P +TR  I   LE L NKR    PKKHGNIPL
Sbjct: 484 GLIDDVIEPKDTRNVIARGLEMLRNKREFRYPKKHGNIPL 523


>gb|AAG19817.1| (AE005066) methylmalonyl-CoA decarboxylase, subunit alpha; MmdA
           [Halobacterium sp. NRC-1]
           Length = 516
           
 Score =  621 bits (1583), Expect = e-177
 Identities = 306/522 (58%), Positives = 388/522 (73%), Gaps = 6/522 (1%)

Query: 1   MGMMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHR 60
           M M E++EDL ++ ++ L  GGE  I+ QH+KGKLTARERI+  LD G+F E+     HR
Sbjct: 1   MTMEERIEDLREQTERALLGGGEARIESQHEKGKLTARERIDYFLDDGTFNELDQLRTHR 60

Query: 61  ATEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA 120
           +T F MD+  LP DGV+TGYG +NGR  FV+A DFTV GGSLGE+ A K+ ++M+ A+E 
Sbjct: 61  STNFDMDETKLPGDGVVTGYGDVNGRTTFVFAHDFTVFGGSLGEVFAEKVTKVMDRAMEV 120

Query: 121 GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG 180
           GAPV+GLNDS GARIQEGVD+L G+ EIF  N   SGVVPQI+AIMGPCAGGAVYSPAI 
Sbjct: 121 GAPVVGLNDSAGARIQEGVDALGGFAEIFTRNEKASGVVPQISAIMGPCAGGAVYSPAIT 180

Query: 181 DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL 240
           DF +MV + S  MFITGP V++ VTG  V   +LGGA  HA +SG AH    S+E  +  
Sbjct: 181 DFTVMVKDTS-HMFITGPDVIETVTGEQVGFEELGGATTHAAESGVAHFACDSEEAALDN 239

Query: 241 IKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENG 300
           IKRLLSYLP NN+E PPRV+P D+P RR   L  IVPD+P K YD+  V+ ++VD     
Sbjct: 240 IKRLLSYLPQNNVEDPPRVEPYDDPERRDDALETIVPDEPRKPYDMTDVVDSVVDEQS-- 297

Query: 301 NPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN 360
              F E+Q  +A N V+GF R++G++VGIVAN P   AG LDID+S+K +RFVRFCD+FN
Sbjct: 298 ---FFEVQADYAKNIVVGFARLDGRSVGIVANQPRVNAGTLDIDASEKGSRFVRFCDSFN 354

Query: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSK 420
           +PI+T VDVPG+LPG DQE  GIIRHGAK+LYA++EA+VP++TVI RKAYGGAY  M SK
Sbjct: 355 VPILTLVDVPGFLPGTDQEHGGIIRHGAKLLYAFSEASVPLMTVITRKAYGGAYDVMASK 414

Query: 421 HLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAA 480
           H+GAD  +AWPTAEIAVMGP+GA N+++  E+  A++    R++ I EYRE+FANPY AA
Sbjct: 415 HIGADVNYAWPTAEIAVMGPKGAVNVLYSDELEAADDTAARRQELIDEYREEFANPYTAA 474

Query: 481 SRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
            RGY+D VI+P ETR +++  L+ L +KR + P KKHGNIPL
Sbjct: 475 DRGYLDAVIEPTETRPRLIDDLDMLASKREETPDKKHGNIPL 516


>pir||T43828 propionyl-CoA carboxylase (EC 6.4.1.3) [validated] - Myxococcus
           xanthus >gi|2627219|dbj|BAA23583.1| (AB007000)
           propionyl-CoA carboxylase [Myxococcus xanthus]
           Length = 524
           
 Score =  616 bits (1571), Expect = e-175
 Identities = 316/506 (62%), Positives = 380/506 (74%), Gaps = 10/506 (1%)

Query: 21  GGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGMDKRDLPADGVITGY 80
           GG + I KQH+ GKLTARERI+LLLDPGSF E+  FV HR++EFGM  + +P  GV+TGY
Sbjct: 25  GGADRIAKQHESGKLTARERIDLLLDPGSFCELDKFVTHRSSEFGMGDKKIPGHGVVTGY 84

Query: 81  GTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVD 140
           GT+ GR VFV+AQDFTV GGSL   +A KI +IM+LA   GAPVIGLNDSGGARIQEGV+
Sbjct: 85  GTVEGRKVFVFAQDFTVFGGSLSGAYAQKICKIMDLATRVGAPVIGLNDSGGARIQEGVE 144

Query: 141 SLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFMFITGPQV 200
           SL GY +IF  NT  SGVVPQI+ IMGPCAGGAVYSPAI DFI+MV + S +MFITGP V
Sbjct: 145 SLAGYADIFVRNTGCSGVVPQISLIMGPCAGGAVYSPAITDFIMMVKDTS-YMFITGPDV 203

Query: 201 VKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSNNMEKPPRVK 260
           +K VT  +V+   LGGA+ H QKSG AH   ++++  I + + LLS+LPSNN E+ P   
Sbjct: 204 IKTVTHEEVSKEALGGAVTHNQKSGVAHFAAENEQAAIVMTRELLSFLPSNNQEEAPVQP 263

Query: 261 PKDEPFR-RTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIGF 319
            +D+ FR R      IVP +PNK YD+++VI AIVD     +  F E+Q +FA N VIGF
Sbjct: 264 CEDDAFRGRRSRSRTIVPSNPNKPYDIKEVIKAIVD-----DKHFFEVQEHFAKNIVIGF 318

Query: 320 GRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPGYLPGVDQE 379
            R+NG+TVG+VAN P  LAGVLDID+S K ARFVRFCD FNIP+VT VDVPG+LPG DQE
Sbjct: 319 ARMNGRTVGVVANQPAVLAGVLDIDASIKAARFVRFCDCFNIPLVTLVDVPGFLPGTDQE 378

Query: 380 SRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADF---VFAWPTAEIA 436
             GII HGAK+LYAYAEATVP VTVI RKAYGGAY  M SKH+ AD     FAWPTAEIA
Sbjct: 379 WGGIITHGAKLLYAYAEATVPKVTVITRKAYGGAYDVMASKHIRADMNFANFAWPTAEIA 438

Query: 437 VMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYIDDVIDPAETRA 496
           VMGPEGA NIIFR E+AKA +    R +   +YR+KFA P+ AA  GYID++I P ETRA
Sbjct: 439 VMGPEGAVNIIFRNELAKAPDAAAERARLTADYRDKFATPFKAAELGYIDEIIRPEETRA 498

Query: 497 KIVMALEALENKRVKLPPKKHGNIPL 522
           K++ +LE L++KR +  P+KHGNIPL
Sbjct: 499 KLIRSLELLKDKRQENLPRKHGNIPL 524


>pir||T44289 probable methylmalonyl-CoA decarboxylase (EC 4.1.1.41) [imported] -
           Sulfolobus metallicus >gi|2792514|gb|AAB97083.1|
           (AF042099) putative carboxyl transferase [Sulfolobus
           metallicus]
           Length = 517
           
 Score =  612 bits (1561), Expect = e-174
 Identities = 293/514 (57%), Positives = 383/514 (74%), Gaps = 5/514 (0%)

Query: 3   MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRAT 62
           M + +E++   + K +  GGE+ IK QH+KGK+TARERI LL D G+F EI  F + ++T
Sbjct: 1   MDKLIEEMKSLKAKAMAGGGEDKIKAQHEKGKMTARERIALLFDEGTFSEIMTFARTQST 60

Query: 63  EFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGA 122
           EFG+DK DL  DGV+TG+G I+GR  FVY+QDFT +GG+LGEMHA KI ++ ELAL+ GA
Sbjct: 61  EFGLDKTDLYGDGVVTGWGKIDGRTAFVYSQDFTSLGGTLGEMHASKIGKVYELALKVGA 120

Query: 123 PVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDF 182
           PVIG+NDSGGARIQEG  SL+GYG +FK N + SGV+PQIT + GP AGGAVYSPA+ DF
Sbjct: 121 PVIGINDSGGARIQEGAASLEGYGLVFKNNVMASGVIPQITIMAGPAAGGAVYSPALTDF 180

Query: 183 ILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIK 242
           ++MV   + +MF+TGP++ K V G DV+   LGGA+VHA KSG  H +  S++E I   K
Sbjct: 181 LIMVKGDAYYMFVTGPEITKVVLGEDVSMQDLGGAVVHASKSGVVHFMVDSEQEAINTAK 240

Query: 243 RLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNP 302
           RLLSYLPSNNME+PP +   D   R   +   IVP D  K +D+R ++YA+VD     N 
Sbjct: 241 RLLSYLPSNNMEEPPYMDTGDTNDREVKDAESIVPTDSAKTFDIRDLVYAVVD-----NG 295

Query: 303 DFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIP 362
           +FLE+  ++A N  +GF R+ G  VGIVANN  + +G +DID++DK ARF+RFCDAFNIP
Sbjct: 296 EFLEVHKHWAQNITVGFARVAGNVVGIVANNSAYASGAIDIDAADKAARFIRFCDAFNIP 355

Query: 363 IVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHL 422
           +V+ VD PGY+PG DQE RGIIRHGAK+LYA+AEATVP +TV++R++YGGA++AM  K L
Sbjct: 356 LVSIVDTPGYIPGTDQEYRGIIRHGAKMLYAFAEATVPKITVVVRRSYGGAHIAMSIKSL 415

Query: 423 GADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASR 482
           GAD ++AWP+AEIAV GPEGA  I+++KE+  A NP+E  KQ+I EY++ FANPY AA +
Sbjct: 416 GADVIYAWPSAEIAVTGPEGAVRILYKKELQAASNPDELLKQRIAEYKKLFANPYWAAKK 475

Query: 483 GYIDDVIDPAETRAKIVMALEALENKRVKLPPKK 516
           G IDDVI+P +TR  I+ AL  L+NKR    PKK
Sbjct: 476 GLIDDVIEPKDTRKVIMSALSMLKNKREYRYPKK 509


>pir||H75410 probable propionyl-CoA carboxylase, alpha subunit - Deinococcus
           radiodurans (strain R1)
           >gi|6459066|gb|AAF10887.1|AE001978_7 (AE001978)
           propionyl-CoA carboxylase, alpha subunit, putative
           [Deinococcus radiodurans]
           Length = 520
           
 Score =  609 bits (1553), Expect = e-173
 Identities = 315/521 (60%), Positives = 388/521 (74%), Gaps = 9/521 (1%)

Query: 3   MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRAT 62
           + E +  + QRR+K+ + GG E  +KQ + GKLTARERIE LLDPGSF+E   FV+H   
Sbjct: 8   LQELIATMEQRRRKVEEGGGPERQQKQREGGKLTARERIERLLDPGSFLESSTFVEHGRN 67

Query: 63  EFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGA 122
              MD  + P +GV+TG GTI+GR VFV++QDFTV+GGSLG+M+A K+ +IM+LA + G 
Sbjct: 68  RL-MDGIEAPGEGVVTGSGTIDGRQVFVFSQDFTVLGGSLGKMNASKVTKIMDLAAKTGC 126

Query: 123 PVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDF 182
           PVIGLNDS GARIQEGVDSL GYGEIF  N + SG VPQI+AI+GPCAGGAVYSPAI DF
Sbjct: 127 PVIGLNDSAGARIQEGVDSLSGYGEIFYRNAVYSGSVPQISAILGPCAGGAVYSPAITDF 186

Query: 183 ILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIK 242
           ILM    S++MFITGP+V+K+VT  +VT  QLGGA VH +KSG AHL  + DE VI  IK
Sbjct: 187 ILM-SRGSSYMFITGPEVIKSVTREEVTFDQLGGADVHTRKSGVAHLAYEGDEAVIDGIK 245

Query: 243 RLLSYLPSNNMEKPPRVKPKDEPF-RRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGN 301
            LL YLP N  EK P VKP  +P  RR  +L DIV  D  + Y ++ VI  +VD     +
Sbjct: 246 DLLGYLPQNAREKAP-VKPTSDPADRRNEKLLDIVTPDQRRPYAMQDVIRELVD-----D 299

Query: 302 PDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNI 361
             FLE+QP +A N ++GF R+NGQ+VGIVANNP  L+G L+ID+SDK ARF+R CD +N+
Sbjct: 300 GTFLEIQPDWAKNIIVGFARLNGQSVGIVANNPKALSGSLNIDASDKAARFIRTCDCYNV 359

Query: 362 PIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKH 421
           PI+T VDV G+LPGV QE  GIIRHGAK+LYAYAEATVP VT+I RK+YGGAYLAM S+ 
Sbjct: 360 PILTLVDVSGFLPGVQQEYGGIIRHGAKMLYAYAEATVPKVTLITRKSYGGAYLAMNSRD 419

Query: 422 LGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAAS 481
           +GAD V+AWPTA +AVMG EGAANI++RK+I  +ENP   R +KI EY+E F NPYVAA+
Sbjct: 420 MGADVVYAWPTATVAVMGAEGAANIVYRKDIKDSENPAATRAEKIAEYKEAFDNPYVAAA 479

Query: 482 RGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           +GYIDDVI   ETR +++   E L NK    P KKHGNIPL
Sbjct: 480 KGYIDDVIPMEETRERLIRTFEMLANKEETRPFKKHGNIPL 520


>pir||A49094 methylmalonyl-CoA decarboxylase (EC 4.1.1.41) alpha chain -
           Veillonella parvula >gi|415593|gb|AAC36820.1| (L22208)
           methylmalonyl-CoA decarboxylase alpha-subunit
           [Veillonella parvula] >gi|415915|emb|CAA80872.1|
           (Z24754) alpha-subunit,methylmalonyl-CoA decarboxylase
           [Veillonella parvula]
           Length = 509
           
 Score =  607 bits (1549), Expect = e-173
 Identities = 300/520 (57%), Positives = 385/520 (73%), Gaps = 14/520 (2%)

Query: 3   MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRAT 62
           + EK+E L+++  K+   GGE+ ++KQH +GK+TARER+  L D  SFVE+  FVKHR  
Sbjct: 4   VQEKIELLHEKLAKVKAGGGEKRVEKQHAQGKMTARERLAKLFDDNSFVELDQFVKHRCV 63

Query: 63  EFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGA 122
            FG +K++LP +GV+TGYGTI+GRLV+ +AQDFTV GGSLGEMHA KI ++  LA++ GA
Sbjct: 64  NFGQEKKELPGEGVVTGYGTIDGRLVYAFAQDFTVEGGSLGEMHAAKIVKVQRLAMKMGA 123

Query: 123 PVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDF 182
           P++G+NDSGGARIQE VD+L GYG+IF  NT  SGV+PQI+ IMGPCAGGAVYSPA+ DF
Sbjct: 124 PIVGINDSGGARIQEAVDALAGYGKIFFENTNASGVIPQISVIMGPCAGGAVYSPALTDF 183

Query: 183 ILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIK 242
           I MV N S  MFITGP V+K+VTG +VT   LGGA+ H   SG AH   +++++ I  I+
Sbjct: 184 IYMVKNTSQ-MFITGPAVIKSVTGEEVTAEDLGGAMAHNSVSGVAHFAAENEDDCIAQIR 242

Query: 243 RLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNP 302
            LL +LPSNNME  P V   D+P R    L  ++PD+ N  YD++ VI A VD     N 
Sbjct: 243 YLLGFLPSNNMEDAPLVDTGDDPTREDESLNSLLPDNSNMPYDMKDVIAATVD-----NG 297

Query: 303 DFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIP 362
           ++ E+QP++A N +  F R +GQ+VGI+AN P  +AG LDI++SDK +RF+RFCDAFNIP
Sbjct: 298 EYYEVQPFYATNIITCFARFDGQSVGIIANQPKVMAGCLDINASDKSSRFIRFCDAFNIP 357

Query: 363 IVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHL 422
           IV FVDVPG+LPG +QE  GIIRHGAK+LYAY+EATVP +TVI RKAYGG+YLAM S+ L
Sbjct: 358 IVNFVDVPGFLPGTNQEWGGIIRHGAKMLYAYSEATVPKITVITRKAYGGSYLAMCSQDL 417

Query: 423 GADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASR 482
           GAD V+AWPT+EIAVMGP GAANIIF+K        +E +  K  +Y E+FA PY AA R
Sbjct: 418 GADQVYAWPTSEIAVMGPAGAANIIFKK--------DEDKDAKTAKYVEEFATPYKAAER 469

Query: 483 GYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           G++D VI+P +TR  ++ AL  L +KR    PKKHGNIPL
Sbjct: 470 GFVDVVIEPKQTRPAVINALAMLASKRENRAPKKHGNIPL 509


>pir||D71667 propionyl-COA carboxylase beta chain precursor (pccB) RP619 -
           Rickettsia prowazekii >gi|3861162|emb|CAA15062.1|
           (AJ235272) PROPIONYL-COA CARBOXYLASE BETA CHAIN
           PRECURSOR (pccB) [Rickettsia prowazekii]
           Length = 514
           
 Score =  600 bits (1530), Expect = e-170
 Identities = 307/516 (59%), Positives = 374/516 (71%), Gaps = 13/516 (2%)

Query: 9   DLYQRRKKILQMGGEEA-IKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGMD 67
           +L   RK I + GG EA I  QH KGKLTARERIE+LLDP SF E GMFV HR   FGM 
Sbjct: 10  ELLDERKNIARQGGGEARINAQHQKGKLTARERIEVLLDPNSFTETGMFVSHRCDNFGMQ 69

Query: 68  KRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGL 127
            +    DGV+TGYGTINGRLVF+Y+QDFTV+GGSLGE HA KI  I++ A+  GAPVIG+
Sbjct: 70  NKKFLGDGVVTGYGTINGRLVFIYSQDFTVLGGSLGEYHAKKICDIIDQAIATGAPVIGI 129

Query: 128 NDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVD 187
           NDSGGARIQEGVD+L GYGE+F+ N + SGV+PQIT IMGPCAGGAVYSPA+ DFI MV 
Sbjct: 130 NDSGGARIQEGVDALAGYGELFQRNVLASGVIPQITLIMGPCAGGAVYSPALTDFIFMVK 189

Query: 188 NPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSY 247
           N S++MF+TGP VVK VTG +VT  +LGGA +H  KSG A L   +D E +  I++  ++
Sbjct: 190 N-SSYMFVTGPDVVKTVTGEEVTQEKLGGARMHTTKSGVADLAFNNDIEALLEIRKFFNF 248

Query: 248 LPSNNMEKPPRVKPKDEPFRRTP-ELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLE 306
           LPS+N    P V+P  +P  R    L  ++P+ PNK YD+++++  IVD  E     F E
Sbjct: 249 LPSSNRSTLP-VRPTVDPADRVDMSLSTLIPNTPNKPYDMKELVERIVDEGE-----FFE 302

Query: 307 LQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTF 366
           LQP FA N +IGFG + G  VG +AN P+HLAG LDI++S K ARF+RFCDAFNI IV+ 
Sbjct: 303 LQPDFAKNIIIGFGYMEGYPVGFIANQPLHLAGCLDINASRKAARFIRFCDAFNISIVSL 362

Query: 367 VDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADF 426
           VDVPG+LPG  QE  GII+HGAK+LYAYAEATVP +TVI RKAYGGAY+ M SKHL  D 
Sbjct: 363 VDVPGFLPGTSQEHEGIIKHGAKLLYAYAEATVPKITVITRKAYGGAYIVMNSKHLRGDI 422

Query: 427 VFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYID 486
            +AW  +EIAVMG EGAA IIF++E        E +KQKI EYR+   +P+VAASRGY+D
Sbjct: 423 NYAWFNSEIAVMGAEGAAEIIFKEEC----KDNEAKKQKIDEYRKVVTSPFVAASRGYLD 478

Query: 487 DVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           D+I P  TR +I  AL  L  K+V LP KKH N+PL
Sbjct: 479 DIIRPQNTRWRICKALNFLRTKKVSLPWKKHDNLPL 514


>sp|P53003|PCCB_SACER PROPIONYL-COA CARBOXYLASE BETA CHAIN (PCCASE) (PROPANOYL-COA:CARBON
           DIOXIDE LIGASE) >gi|2127500|pir||S71008 propionyl-CoA
           carboxylase beta chain homolog - Saccharopolyspora
           erythraea >gi|1177652|emb|CAA63310.1| (X92557)
           propionyl-CoA carboxylase [Saccharopolyspora erythraea]
           Length = 546
           
 Score =  596 bits (1520), Expect = e-169
 Identities = 305/530 (57%), Positives = 379/530 (70%), Gaps = 20/530 (3%)

Query: 6   KVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFG 65
           K+ DLY+R  + +  G E A+ KQH KGK TARERI++LLD GSFVE+    +HR+T FG
Sbjct: 24  KLADLYRRNHEAVHAGSERAVAKQHAKGKRTARERIDMLLDEGSFVELDEHARHRSTNFG 83

Query: 66  MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125
           MD      DGV+TG+GT++GR V V++QDFTV GGSLGE+   KI ++M+LA++ G P++
Sbjct: 84  MDADRPYGDGVVTGWGTVDGRRVCVFSQDFTVFGGSLGEVFGEKIVKVMDLAMKTGCPLV 143

Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185
           G+NDSGGARIQEGV +L  Y EIFK NT  SGV+PQI+ IMGPCAGGAVYSPAI DF +M
Sbjct: 144 GINDSGGARIQEGVAALGLYAEIFKRNTHASGVIPQISLIMGPCAGGAVYSPAITDFTVM 203

Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245
           VD  S  MFITGP V+K VTG DV+   LGGA  H ++SG AH +   +++ I  +K LL
Sbjct: 204 VDQTS-HMFITGPDVIKTVTGEDVSFEDLGGARTHNERSGNAHYLATDEDDAISYVKELL 262

Query: 246 SYLPSNNMEKPPRVKPKDEPFRRTP---------ELYDIVPDDPNKAYDVRQVIYAIVDR 296
           S+LPSNN+   P V P  E    +          EL  +VPD PN+ YD+R+VI  +VD 
Sbjct: 263 SFLPSNNLSSSP-VFPGAEVEEGSVADGVGDADLELDALVPDSPNQPYDMREVITRLVDE 321

Query: 297 DENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFC 356
            E     FLE+   FAPN + GFGRI G +VG+VAN P+ LAG LDID+S+K ARFVRFC
Sbjct: 322 GE-----FLEVSALFAPNMLCGFGRIEGASVGVVANQPMQLAGTLDIDASEKAARFVRFC 376

Query: 357 DAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLA 416
           DAFNIP++T VDVPG+LPG  Q+   IIR GAK+LYAYAEATVP+VTVI RKAYGGAY  
Sbjct: 377 DAFNIPVLTLVDVPGFLPGTGQDWNAIIRRGAKLLYAYAEATVPLVTVITRKAYGGAYDV 436

Query: 417 MGSKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKA----ENPEEFRKQKIQEYREK 472
           MGSKHLGAD   AWPTA+IAVMG +GAANI++R+++A+A    E+ E  R +  QEY + 
Sbjct: 437 MGSKHLGADINLAWPTAQIAVMGAQGAANILYRRQLAEAAERGEDVEALRARLQQEYEDT 496

Query: 473 FANPYVAASRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
             NPYVAA RGY+D VI P+ TR  +  AL  L +KR  LP KKHGNIPL
Sbjct: 497 LCNPYVAAERGYVDSVIPPSHTRGHVARALRMLADKREALPAKKHGNIPL 546


>pir||T42208 propionyl-CoA carboxylase complex B chain - Streptomyces coelicolor
           >gi|4704652|gb|AAD28194.1|AF113605_1 (AF113605)
           propionyl-CoA carboxylase complex B subunit
           [Streptomyces coelicolor A3(2)]
           Length = 530
           
 Score =  596 bits (1520), Expect = e-169
 Identities = 301/521 (57%), Positives = 378/521 (71%), Gaps = 11/521 (2%)

Query: 6   KVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFG 65
           K+ DL +R ++    G   A++KQH KGKLTARERI+LLLD GSFVE+  F +HR+T FG
Sbjct: 17  KLADLRRRIEEATHAGSARAVEKQHAKGKLTARERIDLLLDEGSFVELDEFARHRSTNFG 76

Query: 66  MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125
           +D      DGV+TGYGT++GR V V++QDFTV GG+LGE++  KI ++M+ AL+ G PV+
Sbjct: 77  LDANRPYGDGVVTGYGTVDGRPVAVFSQDFTVFGGALGEVYGQKIVKVMDFALKTGCPVV 136

Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185
           G+NDSGGARIQEGV SL  YGEIF+ NT  SGV+PQI+ ++GPCAGGAVYSPAI DF +M
Sbjct: 137 GINDSGGARIQEGVASLGAYGEIFRRNTHASGVIPQISLVVGPCAGGAVYSPAITDFTVM 196

Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245
           VD  S  MFITGP V+K VTG DV   +LGGA  H   SG AH +   +++ +  +K+LL
Sbjct: 197 VDQTS-HMFITGPDVIKTVTGEDVGFEELGGARTHNSTSGVAHHMAGDEKDAVEYVKQLL 255

Query: 246 SYLPSNNMEKPPRVKPKDEPFRRT---PELYDIVPDDPNKAYDVRQVIYAIVDRDENGNP 302
           SYLPSNN+ +PP   P++     T    EL  IVPD  N+ YD+  VI  ++D     + 
Sbjct: 256 SYLPSNNLSEPPAF-PEEADLAVTDEDAELDTIVPDSANQPYDMHSVIEHVLD-----DA 309

Query: 303 DFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIP 362
           +F E QP FAPN + GFGR+ G+ VGIVAN P+  AG LDI +S+K ARFVR CDAFN+P
Sbjct: 310 EFFETQPLFAPNILTGFGRVEGRPVGIVANQPMQFAGCLDITASEKAARFVRTCDAFNVP 369

Query: 363 IVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHL 422
           ++TFVDVPG+LPGVDQE  GIIR GAK+++AYAEATVP++TVI RKA+GGAY  MGSKHL
Sbjct: 370 VLTFVDVPGFLPGVDQEHDGIIRRGAKLIFAYAEATVPLITVITRKAFGGAYDVMGSKHL 429

Query: 423 GADFVFAWPTAEIAVMGPEGAANIIFRKEIAKA-ENPEEFRKQKIQEYREKFANPYVAAS 481
           GAD   AWPTA+IAVMG +GA NI+ R+ IA A ++ E  R + IQEY +   NPY AA 
Sbjct: 430 GADLNLAWPTAQIAVMGAQGAVNILHRRTIADAGDDAEATRARLIQEYEDALLNPYTAAE 489

Query: 482 RGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           RGY+D VI P++TR  IV  L  L  KR  LPPKKHGNIPL
Sbjct: 490 RGYVDAVIMPSDTRRHIVRGLRQLRTKRESLPPKKHGNIPL 530


>pir||T29065 probable methylmalonyl-CoA decarboxylase (EC 4.1.1.41) -
           Streptomyces coelicolor >gi|3355683|emb|CAA19983.1|
           (AL031124) putative carboxyl transferase [Streptomyces
           coelicolor A3(2)]
           Length = 527
           
 Score =  583 bits (1486), Expect = e-165
 Identities = 290/516 (56%), Positives = 369/516 (71%), Gaps = 6/516 (1%)

Query: 6   KVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFG 65
           +V +L+  R   L    E+A   QH KGKLTARERIELLLDPGSF E+    +HRAT FG
Sbjct: 17  RVAELHGIRAAALAGPSEKATAAQHAKGKLTARERIELLLDPGSFREVEQLRRHRATGFG 76

Query: 66  MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125
           ++ +    DGVITG+GT+ GR VFVYA DF + GG+LGE HA KI +IM++A+ AGAP++
Sbjct: 77  LEAKKPYTDGVITGWGTVEGRTVFVYAHDFRIFGGALGEAHATKIHKIMDMAIAAGAPLV 136

Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185
            LND  GARIQEGV +L GYG IF+ NT  SGV+PQI+ ++GPCAGGA YSPA+ DF+ M
Sbjct: 137 SLNDGAGARIQEGVSALAGYGGIFQRNTKASGVIPQISVMLGPCAGGAAYSPALTDFVFM 196

Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245
           V + S  MFITGP VVKAVTG ++T   LGGA VHA+ SG  H     +E  +  ++ LL
Sbjct: 197 VRDTSQ-MFITGPDVVKAVTGEEITQNGLGGADVHAETSGVCHFAYDDEETCLAEVRYLL 255

Query: 246 SYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFL 305
           S LP NN E PPR +  D   RR+  L D+VP D N+ YD+ +VI  +VD  E     +L
Sbjct: 256 SLLPQNNRENPPRAESSDPVDRRSDTLLDLVPADGNRPYDMTKVIEELVDEGE-----YL 310

Query: 306 ELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVT 365
           E+   +A N +    R++G+ VGIVAN P  LAGVLDI++S+K ARFV+ CDAFNIPI+T
Sbjct: 311 EVHERWARNIICALARLDGRVVGIVANQPQALAGVLDIEASEKAARFVQMCDAFNIPIIT 370

Query: 366 FVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGAD 425
            +DVPG+LPGVDQE  GIIRHGAK+LYAY  ATVP +++ILRKAYGGAY+ M S+ +GAD
Sbjct: 371 LLDVPGFLPGVDQEHGGIIRHGAKLLYAYCNATVPRISLILRKAYGGAYIVMDSQSIGAD 430

Query: 426 FVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYI 485
             +AWPT EIAVMG EGAAN+IFR++IA AE+PE  R + ++EY+ +  +PY AA RG +
Sbjct: 431 LTYAWPTNEIAVMGAEGAANVIFRRQIADAEDPEAMRARMVKEYKSELMHPYYAAERGLV 490

Query: 486 DDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIP 521
           DDVIDPAETR  ++ +L  L  K   LP +KHGN P
Sbjct: 491 DDVIDPAETREVLITSLAMLHTKHADLPSRKHGNPP 526


>sp|P79384|PCCB_PIG PROPIONYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL PRECURSOR
           (PCCASE BETA SUBUNIT) (PROPANOYL-COA:CARBON DIOXIDE
           LIGASE BETA SUBUNIT) >gi|1840397|dbj|BAA19203.1|
           (AB000886) Propionyl-CoA carboxylase beta chain
           precursor [Sus scrofa]
           Length = 539
           
 Score =  562 bits (1433), Expect = e-159
 Identities = 293/517 (56%), Positives = 362/517 (69%), Gaps = 16/517 (3%)

Query: 8   EDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGM- 66
           E +  +R+  L  GG+  I  QH +GKLTARERI LLLDPGSF+E  MFV+HR  +FGM 
Sbjct: 37  ERIENKRQAALLGGGQRRIDSQHKRGKLTARERISLLLDPGSFIESDMFVEHRCADFGMA 96

Query: 67  -DKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125
            DK   P D V+TG G INGRLV+V++QDFTV GGSL   HA KI +IM+ A+  GAPVI
Sbjct: 97  ADKNKFPGDSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAMTVGAPVI 156

Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185
           GLNDSGGARIQEGV+SL GY +IF  N   SGV+PQI+ IMGPCAGGAVYSPA+ DF  M
Sbjct: 157 GLNDSGGARIQEGVESLAGYADIFLRNVSASGVIPQISLIMGPCAGGAVYSPALTDFTFM 216

Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245
           V + S ++FITGP VVK+VT  DVT  +LGGA  H   SG AH    +D + +  ++   
Sbjct: 217 VKDTS-YLFITGPDVVKSVTNEDVTQEELGGARTHTTMSGVAHRAFDNDVDALCNLREFF 275

Query: 246 SYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFL 305
           +YLP +N +  P  +  D   R  PEL  +VP +  +AYD+  +IY+IVD       DF 
Sbjct: 276 NYLPLSNQDPAPIRECHDPSDRLVPELDTVVPLESTRAYDMVDIIYSIVDER-----DFF 330

Query: 306 ELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVT 365
           E+ P +A N ++GF R+NG+TVGIV N P   +G LDI+SS K ARFVRFCDAFNIP++T
Sbjct: 331 EIMPNYAKNIIVGFARMNGRTVGIVGNQPKVASGCLDINSSVKGARFVRFCDAFNIPLIT 390

Query: 366 FVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGAD 425
           FVDVPG+LPG  QE  GIIRHGAK+LYA+AEATVP +TVI RKAYGGAY  M SKHL  D
Sbjct: 391 FVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKITVITRKAYGGAYDVMSSKHLCGD 450

Query: 426 FVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYI 485
             +AWPTAEIAVMG +GA  IIF+      EN E  +     EY EKFANP+ AA RG++
Sbjct: 451 TNYAWPTAEIAVMGAKGAVEIIFKGH----ENVEAAQ----AEYIEKFANPFPAAVRGFV 502

Query: 486 DDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           DD+I P+ TRA+I   L+ L +K+V+ P +KH NIPL
Sbjct: 503 DDIIQPSSTRARICCDLDVLASKKVQRPWRKHANIPL 539


>pir||T45009 propionyl-CoA carboxylase (EC 6.4.1.3) beta chain precursor
           [validated] - human >gi|4127990|emb|CAA07066.1|
           (AJ006487) propionyl-CoA carboxylase [Homo sapiens]
           Length = 539
           
 Score =  558 bits (1423), Expect = e-158
 Identities = 293/517 (56%), Positives = 363/517 (69%), Gaps = 16/517 (3%)

Query: 8   EDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGM- 66
           E +  +R+  L  GG+  I  QH +GKLTARERI LLLDPGSFVE  MFV+HR  +FGM 
Sbjct: 37  ERIENKRRTALLGGGQRRIDAQHKRGKLTARERISLLLDPGSFVESDMFVEHRCADFGMA 96

Query: 67  -DKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125
            DK   P D V+TG G INGRLV+V++QDFTV GGSL   HA KI +IM+ A+  GAPVI
Sbjct: 97  ADKNKFPGDSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVI 156

Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185
           GLNDSGGARIQEGV+SL GY +IF  N   SGV+PQI+ IMGPCAGGAVYSPA+ DF  M
Sbjct: 157 GLNDSGGARIQEGVESLAGYADIFLRNVTASGVIPQISLIMGPCAGGAVYSPALTDFTFM 216

Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245
           V + S ++FITGP VVK+VT  DVT  +LGGA  H   SG AH   ++D + +  ++   
Sbjct: 217 VKDTS-YLFITGPDVVKSVTNEDVTQEELGGAKTHTTMSGVAHRAFENDVDALCNLRDFF 275

Query: 246 SYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFL 305
           +YLP ++ +  P  +  D   R  PEL  IVP +  KAY++  +I+++VD  E     F 
Sbjct: 276 NYLPLSSQDPAPVRECHDPSDRLVPELDTIVPLESTKAYNMVDIIHSVVDERE-----FF 330

Query: 306 ELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVT 365
           E+ P +A N ++GF R+NG+TVGIV N P   +G LDI+SS K ARFVRFCDAFNIP++T
Sbjct: 331 EIMPNYAKNIIVGFARMNGRTVGIVGNQPKVASGCLDINSSVKGARFVRFCDAFNIPLIT 390

Query: 366 FVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGAD 425
           FVDVPG+LPG  QE  GIIRHGAK+LYA+AEATVP VTVI RKAYGGAY  M SKHL  D
Sbjct: 391 FVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKVTVITRKAYGGAYDVMSSKHLCGD 450

Query: 426 FVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYI 485
             +AWPTAEIAVMG +GA  IIF+      EN E  +     EY EKFANP+ AA RG++
Sbjct: 451 TNYAWPTAEIAVMGAKGAVEIIFKGH----ENVEAAQ----AEYIEKFANPFPAAVRGFV 502

Query: 486 DDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           DD+I P+ TRA+I   L+ L +K+V+ P +KH NIPL
Sbjct: 503 DDIIQPSSTRARICCDLDVLASKKVQRPWRKHANIPL 539


>pir||T16428 propionyl-CoA carboxylase (EC 6.4.1.3) beta chain F52E4.1
           [similarity] - Caenorhabditis elegans
           >gi|1293830|gb|AAB54030.1| (U56964) Similar to
           propionyl-CoA carboxylase beta; coded for by C. elegans
           cDNA yk74f9.5; coded for by C. elegans cDNA yk51d4.5;
           coded for by C. elegans cDNA yk90b1.5; coded for by C.
           elegans cDNA yk104d12.5; coded for by C. elegans cDNA
           yk82f4.5; cod>
           Length = 536
           
 Score =  557 bits (1420), Expect = e-157
 Identities = 287/511 (56%), Positives = 360/511 (70%), Gaps = 13/511 (2%)

Query: 12  QRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGMDKRDL 71
           + R+K L  GG++ +  QH +GKLTARERI+LLLD  +F E  MF +H   +FGM K   
Sbjct: 39  ETREKALLGGGKKRVDAQHARGKLTARERIDLLLDRNTFREYDMFAEHTCNDFGMQKEKY 98

Query: 72  PADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSG 131
           P D V+TG G INGR VFV++QDFTV GGSL  +HA KI +IM  A+  GAPVIGLNDSG
Sbjct: 99  PGDSVVTGRGEINGRTVFVFSQDFTVFGGSLSSIHAKKIVKIMREAMLVGAPVIGLNDSG 158

Query: 132 GARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVDNPST 191
           GARIQEGV+SL GY +IF+ N + SGVVPQI+ IMGPCAGGAVYSPA+ DF  MV + S 
Sbjct: 159 GARIQEGVESLAGYADIFQENVMASGVVPQISMIMGPCAGGAVYSPALTDFTFMVRDTS- 217

Query: 192 FMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSN 251
           ++FITGP VVKAVT  +VT  +LGGA  H   SG AH    +D + +  ++ L +YLP +
Sbjct: 218 YLFITGPDVVKAVTNEEVTQEELGGAKTHTVTSGVAHGAFDNDVDALMSLRELFNYLPLS 277

Query: 252 NMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYF 311
           N +  P    +D   R  P L  +VP +   AY+++ V++A+VD       DF E+ P +
Sbjct: 278 NTDAAPIRAAEDPWDRAVPSLDTVVPLESTAAYNMKDVVHALVDEG-----DFFEIMPDY 332

Query: 312 APNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPG 371
           A N VIGF R+NG+TVGIV NNP   AG LDI+SS K ARFVRFCDAFNIPI+T VDVPG
Sbjct: 333 AKNLVIGFARMNGRTVGIVGNNPKFAAGCLDINSSVKGARFVRFCDAFNIPIITLVDVPG 392

Query: 372 YLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAWP 431
           +LPG  QE  GIIRHGAK+LYA+AEATVP +T+I RKA+GGAY  M SKHL  D  +AWP
Sbjct: 393 FLPGTAQEYGGIIRHGAKLLYAFAEATVPKITIITRKAFGGAYDVMSSKHLRGDINYAWP 452

Query: 432 TAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYIDDVIDP 491
           TAE+AVMG +GA +I+FR       N +E   Q  +EY E F+NP+ AA RG++DD+I P
Sbjct: 453 TAEVAVMGAKGAVSILFR-------NDKEHAVQHEEEYTELFSNPFPAAVRGFVDDIIIP 505

Query: 492 AETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           +ETR K+   L  LE+K++K P KKHGNIPL
Sbjct: 506 SETRKKVCEDLNMLESKKLKNPWKKHGNIPL 536


>gi|4557044 propionyl Coenzyme A carboxylase, beta polypeptide [Homo sapiens]
           >gi|1709602|sp|P05166|PCCB_HUMAN PROPIONYL-COA
           CARBOXYLASE BETA CHAIN, MITOCHONDRIAL PRECURSOR (PCCASE
           BETA SUBUNIT) (PROPANOYL-COA:CARBON DIOXIDE LIGASE BETA
           SUBUNIT) >gi|312812|emb|CAA51825.1| (X73424)
           propionyl-CoA carboxylase [Homo sapiens]
           Length = 539
           
 Score =  555 bits (1415), Expect = e-157
 Identities = 292/517 (56%), Positives = 362/517 (69%), Gaps = 16/517 (3%)

Query: 8   EDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGM- 66
           E +  +R+  L  GG+  I  QH +GKLTARERI LLLDPGSFVE  MFV+HR  +FGM 
Sbjct: 37  ERIENKRRTALLGGGQRRIDAQHKRGKLTARERISLLLDPGSFVESDMFVEHRCADFGMA 96

Query: 67  -DKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125
            DK   P D V+TG G INGRLV+V++QDFTV GGSL   HA KI +IM+ A+  GAPVI
Sbjct: 97  ADKNKFPGDSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVI 156

Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185
           GLNDSGGARIQEGV+SL GY +IF  N   SGV+PQI+ IMGPCAGGAVYSPA+ DF  M
Sbjct: 157 GLNDSGGARIQEGVESLAGYADIFLRNVTASGVIPQISLIMGPCAGGAVYSPALTDFTFM 216

Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245
           V + S ++FITGP VVK+VT  DVT  +LGGA  H   SG AH   ++D + +  ++   
Sbjct: 217 VKDTS-YLFITGPDVVKSVTNEDVTQEELGGAKTHTTMSGVAHRAFENDVDALCNLRDFF 275

Query: 246 SYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFL 305
           +YLP ++ +     +  D   R  PEL  IVP +  KAY++  +I+++VD  E     F 
Sbjct: 276 NYLPLSSQDPASVRECHDPSDRLVPELDTIVPLESTKAYNMVDIIHSVVDERE-----FF 330

Query: 306 ELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVT 365
           E+ P +A N ++GF R+NG+TVGIV N P   +G LDI+SS K ARFVRFCDAFNIP++T
Sbjct: 331 EIMPNYAKNIIVGFARMNGRTVGIVGNQPKVASGCLDINSSVKGARFVRFCDAFNIPLIT 390

Query: 366 FVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGAD 425
           FVDVPG+LPG  QE  GIIRHGAK+LYA+AEATVP VTVI RKAYGGAY  M SKHL  D
Sbjct: 391 FVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKVTVITRKAYGGAYDVMSSKHLCGD 450

Query: 426 FVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYI 485
             +AWPTAEIAVMG +GA  IIF+      EN E  +     EY EKFANP+ AA RG++
Sbjct: 451 TNYAWPTAEIAVMGAKGAVEIIFKGH----ENVEAAQ----AEYIEKFANPFPAAVRGFV 502

Query: 486 DDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           DD+I P+ TRA+I   L+ L +K+V+ P +KH NIPL
Sbjct: 503 DDIIQPSSTRARICCDLDVLASKKVQRPWRKHANIPL 539


>gb|AAD13544.1| (AF080235) decarboxylase homolog [Streptomyces cyanogenus]
           Length = 524
           
 Score =  554 bits (1412), Expect = e-157
 Identities = 282/519 (54%), Positives = 361/519 (69%), Gaps = 6/519 (1%)

Query: 3   MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRAT 62
           + +++++L + +++  +     A ++QH KGKLTA ERIELLLD  SF E+    +HRA 
Sbjct: 11  IQDRLDELRELKRQAREGLDPSATERQHAKGKLTAYERIELLLDEDSFNEVEPLRRHRAQ 70

Query: 63  EFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGA 122
            FG++ +    DGVITG+GT+ GR VFVYA DF + GG+LGE HA KI +IM++AL AGA
Sbjct: 71  GFGLEAKKPYTDGVITGWGTVEGRTVFVYAHDFRIFGGALGEAHATKIHKIMDMALSAGA 130

Query: 123 PVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDF 182
           P++ LND  GARIQEGV +L GYG IF+ NT  SGV+PQI+ ++GPCAGGA YSPA+ DF
Sbjct: 131 PLVSLNDGAGARIQEGVTALAGYGGIFQRNTKASGVIPQISVMLGPCAGGAAYSPALTDF 190

Query: 183 ILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIK 242
           + MV   S  MFITGP VVKAVTG ++T   LGGA VHA  SG AH     +E  +  ++
Sbjct: 191 VFMVRETSQ-MFITGPDVVKAVTGEEITQNGLGGADVHAGTSGVAHFAYDDEESCLQEVR 249

Query: 243 RLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNP 302
            LLS LP+NN E  P     D   R T  L  +VP D  ++YD+R VI  IVD  E+   
Sbjct: 250 FLLSLLPANNRELAPVEDSGDPAERLTEALLTLVPADSGRSYDIRAVIEEIVDGGEH--- 306

Query: 303 DFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIP 362
              E+ P +  N V    R++G  VGIVAN P  +AGVLDI+SS+K ARFV+FCDAFNIP
Sbjct: 307 --FEVHPAWGANLVCALARLDGHVVGIVANQPTVMAGVLDIESSEKGARFVQFCDAFNIP 364

Query: 363 IVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHL 422
           +VT VDVPG+LPGVDQE  GIIR GAK+LYAY  ATVP V+++LRKAYGGAY+ M S+ +
Sbjct: 365 LVTLVDVPGFLPGVDQEHSGIIRRGAKLLYAYCNATVPRVSLVLRKAYGGAYIVMDSRSI 424

Query: 423 GADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASR 482
           GAD   AWPT EIAVMG EGAAN+IFR+EI  +++PE  R+Q+I+EYR +  +PY  A R
Sbjct: 425 GADLALAWPTNEIAVMGAEGAANVIFRREINASDDPESVRRQRIKEYRTELMHPYYGAER 484

Query: 483 GYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIP 521
           G IDDVIDP +TR  ++ +L  L  K   LP +KHGN P
Sbjct: 485 GLIDDVIDPRDTRRVLIRSLAMLRAKHADLPSRKHGNPP 523


>pir||A53020 propionyl-CoA carboxylase (EC 6.4.1.3) beta chain precursor - human
           >gi|455713|gb|AAB28900.1| (S67325) propionyl CoA
           carboxylase beta subunit, beta PCC {EC 6.4.1.3} [human,
           liver, placenta, HL 1008, Peptide, 539 aa] [Homo
           sapiens]
           Length = 539
           
 Score =  553 bits (1409), Expect = e-156
 Identities = 291/517 (56%), Positives = 361/517 (69%), Gaps = 16/517 (3%)

Query: 8   EDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGM- 66
           E +  +R+  L  GG+  I     +GKLTARERI LLLDPGSFVE  MFV+HR  +FGM 
Sbjct: 37  ERIENKRRTALLGGGQRRIDAHDKRGKLTARERISLLLDPGSFVESDMFVEHRCADFGMA 96

Query: 67  -DKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125
            DK   P D V+TG G INGRLV+V++QDFTV GGSL   HA KI +IM+ A+  GAPVI
Sbjct: 97  ADKNKFPGDSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVI 156

Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185
           GLNDSGGARIQEGV+SL GY +IF  N   SGV+PQI+ IMGPCAGGAVYSPA+ DF  M
Sbjct: 157 GLNDSGGARIQEGVESLAGYADIFLRNVTASGVIPQISLIMGPCAGGAVYSPALTDFTFM 216

Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245
           V + S ++FITGP VVK+VT  DVT  +LGGA  H   SG AH   ++D + +  ++   
Sbjct: 217 VKDTS-YLFITGPDVVKSVTNEDVTQEELGGAKTHTTMSGVAHRAFENDVDALCNLRDFF 275

Query: 246 SYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFL 305
           +YLP ++ +  P  +  D   R  PEL  IVP +  KAY++  +I+++VD  E     F 
Sbjct: 276 NYLPLSSQDPAPVRECHDPSDRLVPELDTIVPLESTKAYNMVDIIHSVVDERE-----FF 330

Query: 306 ELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVT 365
           E+ P +A N ++GF R+NG+TVGIV N P   +G LDI+SS K ARFVRFCDAFNIP++T
Sbjct: 331 EIMPNYAKNIIVGFARMNGRTVGIVGNQPKVASGCLDINSSVKGARFVRFCDAFNIPLIT 390

Query: 366 FVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGAD 425
           FVDVPG+LPG  QE  GIIRHGAK+LYA+AEATVP VTVI RKAYGGAY  M SKHL  D
Sbjct: 391 FVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKVTVITRKAYGGAYDVMSSKHLCGD 450

Query: 426 FVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYI 485
             +AWPTAEIAVMG +GA  IIF+      EN E  +     EY EKFANP+ AA RG++
Sbjct: 451 TNYAWPTAEIAVMGAKGAVEIIFKGH----ENVEAAQ----AEYIEKFANPFPAAVRGFV 502

Query: 486 DDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           DD+I P+ TRA+I   L+ L +K+V+ P +KH NIPL
Sbjct: 503 DDIIQPSSTRARICCDLDVLASKKVQRPWRKHANIPL 539


>pir||A70980 probable accD5 protein - Mycobacterium tuberculosis (strain H37RV)
           >gi|1877335|emb|CAB07063.1| (Z92771) accD5
           [Mycobacterium tuberculosis]
           Length = 548
           
 Score =  552 bits (1408), Expect = e-156
 Identities = 284/528 (53%), Positives = 364/528 (68%), Gaps = 18/528 (3%)

Query: 6   KVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFG 65
           K+ +L++RR++ L   GE+A++K H KGKLTARERI  LLD  SFVE+    KHR+T F 
Sbjct: 28  KLAELHKRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDSFVELDALAKHRSTNFN 87

Query: 66  MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125
           + ++    DGV+TGYGTI+GR V +++QD TV GGSLGE++  KI ++ ELA++ G P+I
Sbjct: 88  LGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLI 147

Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185
           G+ND  GARIQEGV SL  Y  IF+ N + SGV+PQI+ IMG  AGG VYSPA+ DF++M
Sbjct: 148 GINDGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPALTDFVIM 207

Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245
           VD  S  MFITGP V+K VTG +VT  +LGGA  H  KSG AH     +++    ++ LL
Sbjct: 208 VDQTSQ-MFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQDAFDYVRELL 266

Query: 246 SYLPSNNMEKPPRVK------PKDEPFRRTP-ELYDIVPDDPNKAYDVRQVIYAIVDRDE 298
           SYLP NN    PR +      P +E       EL  ++PD PN+ YD+ +VI  ++D   
Sbjct: 267 SYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQPYDMHEVITRLLD--- 323

Query: 299 NGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDA 358
               +FLE+Q  +A N V+GFGRI+G+ VGIVAN P H AG LDI++S+K ARFVR CD 
Sbjct: 324 ---DEFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFAGCLDINASEKAARFVRTCDC 380

Query: 359 FNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMG 418
           FNIPIV  VDVPG+LPG DQE  GIIR GAK+LYAY EATVP +TVI RKAYGGAY  MG
Sbjct: 381 FNIPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMG 440

Query: 419 SKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKA----ENPEEFRKQKIQEYREKFA 474
           SK +G D   AWPTA+IAVMG  GA   ++R+++A+A    E+ ++ R +  QEY +   
Sbjct: 441 SKDMGCDVNLAWPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEYEDTLV 500

Query: 475 NPYVAASRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           NPYVAA RGY+D VI P+ TR  I  AL  LE K  +LPPKKHGN+PL
Sbjct: 501 NPYVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPPKKHGNVPL 548


>sp|P54541|PCCB_BACSU PUTATIVE PROPIONYL-COA CARBOXYLASE BETA CHAIN (PCCASE)
           (PROPANOYL-COA:CARBON DIOXIDE LIGASE)
           >gi|7438115|pir||D69963 propionyl-CoA carboxylase
           homolog yqjD - Bacillus subtilis
           >gi|1303955|dbj|BAA12610.1| (D84432) YqjD [Bacillus
           subtilis] >gi|2634826|emb|CAB14323.1| (Z99116) similar
           to propionyl-CoA carboxylase [Bacillus subtilis]
           Length = 506
           
 Score =  551 bits (1404), Expect = e-156
 Identities = 281/511 (54%), Positives = 366/511 (70%), Gaps = 13/511 (2%)

Query: 12  QRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGMDKRDL 71
           + RK+  + GG E + +Q  KGKLTARERI  LLD  SF+E+  F++ +       ++ +
Sbjct: 9   RNRKQAEEGGGREKLAQQRQKGKLTARERIIFLLDQDSFIELHPFMESQVLT---REQRM 65

Query: 72  PADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSG 131
             DGV+TGYGTI+GR V+V+AQDFTV GG+LGE HA KI  +M+LA +  AP+IGLNDSG
Sbjct: 66  LGDGVVTGYGTIDGRSVYVFAQDFTVYGGALGETHARKICALMDLAAKNKAPIIGLNDSG 125

Query: 132 GARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVDNPST 191
           GARIQEGV SL GYG IF  N + SGV+PQI+ I+GPCAGGAVYSPA+ DFI M +    
Sbjct: 126 GARIQEGVLSLDGYGHIFYRNVLYSGVIPQISVILGPCAGGAVYSPALTDFIFMAEQTGR 185

Query: 192 FMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSN 251
            MFITGP+V++ VTG  V    LGGA +H   SG AH  G +++EV+  +++LLSYLP N
Sbjct: 186 -MFITGPKVIEKVTGEQVDAESLGGAGIHNAVSGNAHFSGHTEKEVLTGVRKLLSYLPLN 244

Query: 252 NMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYF 311
                P  KP+ E  R  P L  +VP D  K YDVR+VI  + D        F E+QP+F
Sbjct: 245 GRTTEP--KPEKEASR--PLLNRLVPADTTKPYDVRKVIRELADPQS-----FFEIQPFF 295

Query: 312 APNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPG 371
           A N VIGF R+  + +GIVA+ P HLAG L ID++DK ARF+RFCDAF+IP++T  DVPG
Sbjct: 296 AKNIVIGFARLGEKAIGIVASQPKHLAGSLTIDAADKAARFIRFCDAFDIPLLTVEDVPG 355

Query: 372 YLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAWP 431
           +LPG+ QE  GIIRHGAK+L+AYAEATVP VT+I+RKAYGGAY+AM SK +GAD VFAWP
Sbjct: 356 FLPGIQQEHNGIIRHGAKLLFAYAEATVPKVTLIIRKAYGGAYVAMNSKAIGADLVFAWP 415

Query: 432 TAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYIDDVIDP 491
            AEIAVMGPEGAA+I++ KEI  + +P++ +++K  EY+++ A PY AA+ G +DD+I P
Sbjct: 416 NAEIAVMGPEGAASILYEKEIKASADPQKTKREKTAEYKKQNAGPYKAAACGMVDDIILP 475

Query: 492 AETRAKIVMALEALENKRVKLPPKKHGNIPL 522
            E+R +++ A   L +K  + P KKHGNIPL
Sbjct: 476 EESRGRLIQAFHMLTHKTEERPKKKHGNIPL 506


>gi|8393913 propionyl Coenzyme A carboxylase, beta polypeptide [Rattus
           norvegicus] >gi|129686|sp|P07633|PCCB_RAT PROPIONYL-COA
           CARBOXYLASE BETA CHAIN, MITOCHONDRIAL PRECURSOR (PCCASE
           BETA SUBUNIT) (PROPANOYL-COA:CARBON DIOXIDE LIGASE BETA
           SUBUNIT) >gi|92655|pir||A25516 propionyl-CoA carboxylase
           (EC 6.4.1.3) beta chain precursor - rat
           >gi|206042|gb|AAA41818.1| (M14634) prepropionyl-CoA
           carboxylase (EC 6.4.1.3) [Rattus norvegicus]
           Length = 541
           
 Score =  550 bits (1403), Expect = e-155
 Identities = 288/519 (55%), Positives = 362/519 (69%), Gaps = 20/519 (3%)

Query: 8   EDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGM- 66
           E +  +R   L  GG+  I  QH +GKLTARERI LLLDPGSF+E  MFV+HR  +FGM 
Sbjct: 39  ERIENKRHAALLGGGQRRIDAQHKRGKLTARERISLLLDPGSFLESDMFVEHRCADFGMA 98

Query: 67  -DKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125
            +K   P D V+TG G INGRLV+V++QDFTV GGSL   HA KI +IM+ A+  GAPVI
Sbjct: 99  AEKNKFPGDSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVI 158

Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185
           GLNDSGGARIQEGV+SL GY +IF  N   SGV+PQI+ IMGPCAGGAVYSPA+ DF  M
Sbjct: 159 GLNDSGGARIQEGVESLAGYADIFLRNVTASGVIPQISLIMGPCAGGAVYSPALTDFTFM 218

Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245
           V + S ++FITGP+ VK+VT  DVT  QLGGA  H   SG AH    +D + +  ++  L
Sbjct: 219 VKDTS-YLFITGPEFVKSVTNEDVTQEQLGGAKTHTTVSGVAHRAFDNDVDALCNLREFL 277

Query: 246 SYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFL 305
           ++LP +N +     +  D   R  PEL  +VP + +KAY++  +I+A++D  E     F 
Sbjct: 278 NFLPLSNQDPASIRECHDPSDRLVPELDTVVPLESSKAYNMLDIIHAVIDERE-----FF 332

Query: 306 ELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVT 365
           E+ P +A N VIGF R+NG+TVGIV N P   +G LDI+SS K ARFVRFCDAF+IP++T
Sbjct: 333 EIMPNYAKNIVIGFARMNGRTVGIVGNQPNVASGCLDINSSVKGARFVRFCDAFSIPLIT 392

Query: 366 FVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGAD 425
           FVDVPG+LPG  QE  GIIRHGAK+LYA+AEATVP +TVI RKAYGGAY  M SKHL  D
Sbjct: 393 FVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKITVITRKAYGGAYDVMSSKHLLGD 452

Query: 426 FVFAWPTAEIAVMGPEGAANIIFR--KEIAKAENPEEFRKQKIQEYREKFANPYVAASRG 483
             +AWPTAEIAVMG +GA  IIF+  +++  A+           EY EKFANP+ AA RG
Sbjct: 453 TNYAWPTAEIAVMGAKGAVEIIFKGHEDVEAAQ----------AEYVEKFANPFPAAVRG 502

Query: 484 YIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           ++DD+I P+ TRA+I   LE L +K+V  P +KH N+PL
Sbjct: 503 FVDDIIQPSSTRARICCDLEVLASKKVHRPWRKHANVPL 541


>sp|P53002|PCCB_MYCLE PROBABLE PROPIONYL-COA CARBOXYLASE BETA CHAIN (PCCASE)
           (PROPANOYL-COA:CARBON DIOXIDE LIGASE)
           >gi|466841|gb|AAA85917.1| (U00012) pccB; B1308_C1_125
           [Mycobacterium leprae]
           Length = 549
           
 Score =  550 bits (1401), Expect = e-155
 Identities = 283/528 (53%), Positives = 360/528 (67%), Gaps = 17/528 (3%)

Query: 6   KVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFG 65
           K+ +L++R ++ L   G  A +K H KGK TARERI  LLD  SFVE+    +HR+T FG
Sbjct: 28  KLAELHKRTEEALHPVGAAAFEKVHAKGKFTARERIYALLDDDSFVELDALARHRSTNFG 87

Query: 66  MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125
           + +     DGV+TGYGTI+GR V +++QD TV GGSLGE++  KI ++ ELA++ G P+I
Sbjct: 88  LGENRPVGDGVVTGYGTIDGRDVCIFSQDVTVFGGSLGEVYGEKIVKVQELAIKTGRPLI 147

Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185
           G+ND  GARIQEGV SL  Y  IF+ N + SGV+PQI+ IMG  AGG VYSPA+ DF++M
Sbjct: 148 GINDGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPALTDFVVM 207

Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245
           VD  S  MFITGP V+K VTG DVT  +LGGA  H  KSG AH +   +++    ++ +L
Sbjct: 208 VDQTSQ-MFITGPDVIKTVTGEDVTMEELGGAHTHMAKSGTAHYVASGEQDAFDWVRDVL 266

Query: 246 SYLPSNNMEKPPRV-KP------KDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDE 298
           SYLPSNN    PR  KP      +D    +  EL  ++PD PN+ YD+ +V+  ++D +E
Sbjct: 267 SYLPSNNFTDAPRYSKPVPHGSIEDNLTAKDLELDTLIPDSPNQPYDMHEVVTRLLDEEE 326

Query: 299 NGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDA 358
                FLE+Q  +A N V+G GRI+ + VGIVAN PI  AG LDI++S+K ARFVR CD 
Sbjct: 327 -----FLEVQAGYATNIVVGLGRIDDRPVGIVANQPIQFAGCLDINASEKAARFVRVCDC 381

Query: 359 FNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMG 418
           FNIPIV  VDVPG+LPG +QE  GIIR GAK+L+AY EATVP +TVI RKAYGGAY  MG
Sbjct: 382 FNIPIVMLVDVPGFLPGTEQEYDGIIRRGAKLLFAYGEATVPKITVITRKAYGGAYCVMG 441

Query: 419 SKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKA----ENPEEFRKQKIQEYREKFA 474
           SK++G D   AWPTA+IAVMG  GA   ++RKE+A+A     N +E R Q  QEY +   
Sbjct: 442 SKNMGCDVNLAWPTAQIAVMGASGAVGFVYRKELAQAAKNGANVDELRLQLQQEYEDTLV 501

Query: 475 NPYVAASRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           NPY+AA RGY+D VI P+ TR  I  AL  LE K   LPPKKHGNIPL
Sbjct: 502 NPYIAAERGYVDAVIPPSHTRGYIATALHLLERKIAHLPPKKHGNIPL 549


>dbj|BAA33850.1| (AB018531) dtsR2 [Corynebacterium glutamicum]
           Length = 537
           
 Score =  538 bits (1371), Expect = e-152
 Identities = 282/528 (53%), Positives = 355/528 (66%), Gaps = 17/528 (3%)

Query: 6   KVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFG 65
           K+ DL  R  +     GE  ++K H  G+ TARERIE LLD GSFVEI    +HR+  FG
Sbjct: 16  KLSDLRSRLAEAQAPMGEATVEKVHAAGRKTARERIEYLLDEGSFVEIDALARHRSKNFG 75

Query: 66  MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125
           +D +    DGV+TGYGTI+GR V V++QD  V GG+LGE++  KI ++M+LA++ G P+I
Sbjct: 76  LDAKRPATDGVVTGYGTIDGRKVCVFSQDGAVFGGALGEVYGEKIVKVMDLAIKTGVPLI 135

Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185
           G+N+  GARIQEGV SL  Y +IF  NT  SGV+PQI+ IMG CAGG VYSPA+ DFI+M
Sbjct: 136 GINEGAGARIQEGVVSLGLYSQIFYRNTQASGVIPQISLIMGACAGGHVYSPALTDFIVM 195

Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245
           VD  S  MFITGP V+K VTG DVT  +LGGA  H   SG +H     D + +  ++ L 
Sbjct: 196 VDQTSK-MFITGPDVIKTVTGEDVTQEELGGAHTHMATSGTSHYSASDDSDALDWVRELT 254

Query: 246 SYLPSNNMEKPPRVKPK------DEPFRRTP-ELYDIVPDDPNKAYDVRQVIYAIVDRDE 298
           SYLPSNN  + PR +         E       EL  I+PD PN+ YD+++VI  IVD   
Sbjct: 255 SYLPSNNRAETPRQEADIMIGSIQENINDVDLELDTIIPDSPNQPYDMKEVISRIVD--- 311

Query: 299 NGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDA 358
             + +F E+Q  +A N + GF R+ G++VGIVAN P   AG LDI +S+K ARF+R CDA
Sbjct: 312 --DAEFFEIQEDYAENILCGFARVEGRSVGIVANQPTQFAGCLDIKASEKAARFIRTCDA 369

Query: 359 FNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMG 418
           FNIPI+ FVDVPG+LPG +QE  GIIR GAK+LYAYAEATV  +TVI RK+YGGAY  MG
Sbjct: 370 FNIPILEFVDVPGFLPGTNQEFDGIIRRGAKLLYAYAEATVGKITVITRKSYGGAYCVMG 429

Query: 419 SKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKA----ENPEEFRKQKIQEYREKFA 474
           SK +GAD VFAWPTA+IAVMG  GA   I+RKE+ +A    ++  E  K   QEY E   
Sbjct: 430 SKDMGADLVFAWPTAQIAVMGASGAVGFIYRKELKQAATEGKDVAEVMKGYEQEYEETLV 489

Query: 475 NPYVAASRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           NPYVAA RG +D VI P+ETR +I+  L  L+ K V +P KKHGNIPL
Sbjct: 490 NPYVAAERGLVDAVIPPSETRGQIIEGLRLLDRKVVNVPAKKHGNIPL 537


>pir||JC4991 detergent sensitivity rescuer - Corynebacterium glutamicum
           >gi|3767579|dbj|BAA33848.1| (AB018530) dtsR
           [Corynebacterium glutamicum] >gi|3767581|dbj|BAA33849.1|
           (AB018531) dtsR1 [Corynebacterium glutamicum]
           Length = 543
           
 Score =  501 bits (1276), Expect = e-141
 Identities = 267/529 (50%), Positives = 342/529 (64%), Gaps = 19/529 (3%)

Query: 6   KVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFG 65
           K+ DL  RR +     GE+A++K H  G+LTARER++ LLD GSF+E     +HR T FG
Sbjct: 22  KIADLKARRAEAHFPMGEKAVEKVHAAGRLTARERLDYLLDEGSFIETDQLARHRTTAFG 81

Query: 66  MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125
           +  +    DG++TG+GTI+GR V +++QD TV GG+LGE++  K+ +IMELA++ G P+I
Sbjct: 82  LGAKRPATDGIVTGWGTIDGREVCIFSQDGTVFGGALGEVYGEKMIKIMELAIDTGRPLI 141

Query: 126 GLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILM 185
           GL +  GARIQ+G  SL    + F  N   SGV+PQI+ IMG CAGG  Y PA+ DF++M
Sbjct: 142 GLYEGAGARIQDGAVSLDFISQTFYQNIQASGVIPQISVIMGACAGGNAYGPALTDFVVM 201

Query: 186 VDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL 245
           VD  S  MF+TGP V+K VTG ++T  +LGGA  H   +G +H    +DEE +  ++ L+
Sbjct: 202 VDKTSK-MFVTGPDVIKTVTGEEITQEELGGATTHMVTAGNSHYTAATDEEALDWVQDLV 260

Query: 246 SYLPSNNMEKPPRVKPKDEPFRRTPE--------LYDIVPDDPNKAYDVRQVIYAIVDRD 297
           S+LPSNN    P ++  DE      E        L +I+PD     YDVR VI  + D  
Sbjct: 261 SFLPSNNRSYTP-LEDFDEEEGGVEENITADDLKLDEIIPDSATVPYDVRDVIECLTDDG 319

Query: 298 ENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCD 357
           E     +LE+Q   A N VI FGRI GQ+VG VAN P   AG LDIDSS+K ARFVR CD
Sbjct: 320 E-----YLEIQADRAENVVIAFGRIEGQSVGFVANQPTQFAGCLDIDSSEKAARFVRTCD 374

Query: 358 AFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAM 417
           AFNIPIV  VDVPG+LPG  QE  GI+R GAK+LYAY EATVP +TV +RKAYGGAY  M
Sbjct: 375 AFNIPIVMLVDVPGFLPGAGQEYGGILRRGAKLLYAYGEATVPKITVTMRKAYGGAYCVM 434

Query: 418 GSKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEI----AKAENPEEFRKQKIQEYREKF 473
           GSK LG+D   AWPTA+IAVMG  GA   I+RKE+    AK  +     K   +EY +  
Sbjct: 435 GSKGLGSDINLAWPTAQIAVMGAAGAVGFIYRKELMAADAKGLDTVALAKSFEREYEDHM 494

Query: 474 ANPYVAASRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
            NPY AA RG ID VI P+ETR +I   L  L++K V  P +KHGN+PL
Sbjct: 495 LNPYHAAERGLIDAVILPSETRGQISRNLRLLKHKNVTRPARKHGNMPL 543


>pir||A48665 methylmalonyl-CoA carboxyltransferase (EC 2.1.3.1) 12S chain -
           Propionibacterium freudenreichii subsp. shermanii
           >gi|150933|gb|AAA25676.1| (L04196) methylmalonyl-CoA
           carboxyltransferase subunit 12S monomer
           [Propionibacterium freudenreichii subsp. shermanii]
           Length = 605
           
 Score =  450 bits (1146), Expect = e-125
 Identities = 265/520 (50%), Positives = 331/520 (62%), Gaps = 14/520 (2%)

Query: 3   MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRAT 62
           M  +VE L ++R+ I   GGE  ++KQH +GK TARER+  LLDP SF E+G F KHR T
Sbjct: 13  MEGRVEQLAEQRQVIEAGGGERLVEKQHSQGKQTARERLNNLLDPHSFDEVGAFRKHRTT 72

Query: 63  EFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGA 122
            FGMDK  +PADGV+TG GTI GR V   +QDFTVMGGS       + +R    AL  G 
Sbjct: 73  LFGMDKAVVPADGVVTGRGTILGRPVHAASQDFTVMGGSAWRDAVHEGRRDDGTALLTGT 132

Query: 123 PVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDF 182
           P +   DSGG RIQEG+DSL GYG++F  N  LSGVVPQI  I GPCA  A YSPA+ DF
Sbjct: 133 PFLFFYDSGG-RIQEGIDSLSGYGKMFFANVKLSGVVPQIAIIAGPCA-CASYSPALTDF 190

Query: 183 ILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIK 242
           I+M       MFITGPQV+K+VTG DVT  +LGGA      S   + + + D+    + K
Sbjct: 191 IIM--TKKAHMFITGPQVIKSVTGEDVTADELGGA-EPIWPSRAIYFVAEDDDAAELIAK 247

Query: 243 RLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNP 302
           +LLS+LP NN E+   V P ++    T EL DIVP D  K YDVR VI  IVD       
Sbjct: 248 KLLSFLPQNNTEEASFVNPNNDVSPNT-ELRDIVPIDGKKGYDVRDVIAKIVDWG----- 301

Query: 303 DFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIP 362
           D+LE++  +A N V  F R+NG++VGIVAN P  ++G LDI++SDK A FV FCD+FNIP
Sbjct: 302 DYLEVKAGYATNLVTAFARVNGRSVGIVANQPSVMSGCLDINASDKAAEFVNFCDSFNIP 361

Query: 363 IVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHL 422
           +V  VDVPG+LP V QE  GIIRHG K+LYAY+EATVP +T +        +    +  L
Sbjct: 362 LVQLVDVPGFLP-VQQEYGGIIRHGRKMLYAYSEATVPKITCLATPTAAPTW-PCATVTL 419

Query: 423 GADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASR 482
                   P+AEIAVMG EGAAN+IFRKEI  A++P+  R +KI+EY +  +      +R
Sbjct: 420 VPTPCTPVPSAEIAVMGAEGAANVIFRKEIKAADDPDAMRAEKIEEY-QNGSTRRTWRAR 478

Query: 483 GYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           G +DDVIDPA+TR KI  ALE    KR   P KK   +PL
Sbjct: 479 GQVDDVIDPADTRRKIASALEMYATKRQTRPAKKPWKLPL 518


>pir||C70887 probable Propionyl-CoA carboxylase - Mycobacterium tuberculosis
           (strain H37RV) >gi|2950418|emb|CAA17863.1| (AL022076)
           accD4 [Mycobacterium tuberculosis]
           Length = 518
           
 Score =  439 bits (1118), Expect = e-122
 Identities = 234/509 (45%), Positives = 325/509 (62%), Gaps = 15/509 (2%)

Query: 5   EKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEF 64
           EK+ +L +R +   + GGE+A  K+  KG  +AR RI  L+DPGSF+EIG   +      
Sbjct: 13  EKLAELRERLELAKEPGGEKAAAKRDKKGIPSARARIYELVDPGSFMEIGALCRTPG--- 69

Query: 65  GMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPV 124
             D   L  DGV+TG+G INGR V V++ D TV GG++GEM   K+ R+ME     G P+
Sbjct: 70  --DPNALYGDGVVTGHGLINGRPVGVFSHDQTVFGGTVGEMFGRKVARLMEWCAMVGCPI 127

Query: 125 IGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFIL 184
           +G+NDSGGARIQ+ V SL  Y E+ + + +LSG+VPQI+ I+G CAGGAVYSP   D ++
Sbjct: 128 VGINDSGGARIQDAVTSLAWYAELGRRHELLSGLVPQISIILGKCAGGAVYSPIQTDLVV 187

Query: 185 MVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRL 244
            V +   +MF+TGP V+K VTG DV+  +LGGA  H    G  H + +S+      ++  
Sbjct: 188 AVRDQG-YMFVTGPDVIKDVTGEDVSLDELGGA-DHQASYGNIHQVVESEAAAYQYVRDF 245

Query: 245 LSYLPSNNMEKPPRVKPKDEP--FRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNP 302
           LS+LPSN  +KPP V P  EP       EL  IVPD  N AYD+ +V+  I D     + 
Sbjct: 246 LSFLPSNCFDKPPVVNPGLEPEITGHDLELDSIVPDSDNMAYDMHEVLLRIFD-----DG 300

Query: 303 DFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIP 362
           DFL++        + G+ R++G+TVG+VAN P+H++G +D ++SDK ARF+RF DAF+IP
Sbjct: 301 DFLDVAAQAGQAIITGYARVDGRTVGVVANQPMHMSGAIDNEASDKAARFIRFSDAFDIP 360

Query: 363 IVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHL 422
           +V  VD PG+LPGV+QE  GII+ G + LYA  EA VP VT+ +RK+YGGAY  MGSK L
Sbjct: 361 LVFVVDTPGFLPGVEQEKNGIIKRGGRFLYAVVEADVPKVTITIRKSYGGAYAVMGSKQL 420

Query: 423 GADFVFAWPTAEIAVMGPEGAANIIFRK-EIAKAENPEEFRKQKIQEYREKFANPYVAAS 481
            AD  FAWPTA IAV+G +GAA ++ ++     A   +  RK  ++ Y    A P++AA 
Sbjct: 421 TADLNFAWPTARIAVIGADGAAQLLMKRFPDPNAPEAQAIRKSFVENYNLNMAIPWIAAE 480

Query: 482 RGYIDDVIDPAETRAKIVMALEALENKRV 510
           RG+ID VIDP ETR  +  ++  L +K++
Sbjct: 481 RGFIDAVIDPHETRLLLRKSMHLLRDKQL 509


>sp|Q10506|PCCB_MYCTU PROBABLE PROPIONYL-COA CARBOXYLASE BETA CHAIN (PCCASE)
           (PROPANOYL-COA:CARBON DIOXIDE LIGASE)
           >gi|7438117|pir||C70779 probable accD6 protein -
           Mycobacterium tuberculosis (strain H37RV)
           >gi|3261571|emb|CAA94668.1| (Z70692) accD6
           [Mycobacterium tuberculosis]
           Length = 473
           
 Score =  351 bits (891), Expect = 1e-95
 Identities = 196/491 (39%), Positives = 290/491 (58%), Gaps = 23/491 (4%)

Query: 35  LTARERIELLLDPGS-FVEIGMFVKHRATEFGMDKRDLPADGVITGYGTINGRLVFVYAQ 93
           + A E +   LDP    + +  F    + E  + +RD    GV+   GT+NG     +  
Sbjct: 3   IMAPEAVGESLDPRDPLLRLSNFFDDGSVEL-LHERD--RSGVLAAAGTVNGVRTIAFCT 59

Query: 94  DFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNT 153
           D TVMGG++G      I    + A+E  +P++G+  SGGAR+ EGV +L   G++F+   
Sbjct: 60  DGTVMGGAMGVEGCTHIVNAYDTAIEDQSPIVGIWHSGGARLAEGVRALHAVGQVFEAMI 119

Query: 154 ILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQ 213
             SG +PQI+ ++G  AGGA Y PA+ D ++M   P + +F+TGP VV++VTG DV    
Sbjct: 120 RASGYIPQISVVVGFAAGGAAYGPALTDVVVMA--PESRVFVTGPDVVRSVTGEDVDMAS 177

Query: 214 LGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELY 273
           LGG   H +KSG  H++   + +     +RL+            + +  D       +++
Sbjct: 178 LGGPETHHKKSGVCHIVADDELDAYDRGRRLVGLFCQQGHFDRSKAEAGDT------DIH 231

Query: 274 DIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANN 333
            ++P+   +AYDVR ++ AI+D D      F E Q  +AP+ V+G GR++G+TVG++ANN
Sbjct: 232 ALLPESSRRAYDVRPIVTAILDADT----PFDEFQANWAPSMVVGLGRLSGRTVGVLANN 287

Query: 334 PIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYA 393
           P+ L G L+ +S++K ARFVR CDAF IP+V  VDVPGYLPGVDQE  G++R GAK+L+A
Sbjct: 288 PLRLGGCLNSESAEKAARFVRLCDAFGIPLVVVVDVPGYLPGVDQEWGGVVRRGAKLLHA 347

Query: 394 YAEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIA 453
           + E TVP VT++ RK YGGAY+AM S+ L A  VFAWP AE+AVMG + A  I+ +K++A
Sbjct: 348 FGECTVPRVTLVTRKTYGGAYIAMNSRSLNATKVFAWPDAEVAVMGAKAAVGILHKKKLA 407

Query: 454 KA-ENPEEFRKQKIQEYREKFANPYVAA-SRGYIDDVIDPAETRAKIVMALEALENKRVK 511
            A E+  E    ++    E+ A    +A   G +D+ IDPA TR+K+  AL     +R  
Sbjct: 408 AAPEHEREALHDQLAAEHERIAGGVDSALDIGVVDEKIDPAHTRSKLTEALAQAPARR-- 465

Query: 512 LPPKKHGNIPL 522
               +H NIPL
Sbjct: 466 ---GRHKNIPL 473


>pir||T44709 acetyl/propionyl CoA carboxylase [imported] - Mycobacterium leprae
           >gi|3150227|emb|CAA19199.1| (AL023635) Acetyl/Propionyl
           CoA Carboxylase [Mycobacterium leprae]
           Length = 473
           
 Score =  344 bits (872), Expect = 2e-93
 Identities = 186/450 (41%), Positives = 268/450 (59%), Gaps = 19/450 (4%)

Query: 75  GVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGAR 134
           GV    GT+NG     +  D TVMGG++G      I    + A+E  +P++G+  SGGAR
Sbjct: 41  GVFAATGTVNGLRTIAFCTDGTVMGGAMGIEGCAHIVNAYDTAIEEQSPIVGIWHSGGAR 100

Query: 135 IQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFMF 194
           + EGV +L   G++F+     SG +PQI+ ++G  AGGA Y PA+ D ++M   P   +F
Sbjct: 101 LAEGVRALHAVGQVFEAMIRASGYIPQISVVVGFAAGGAAYGPALTDVVIMA--PEGRVF 158

Query: 195 ITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSNNME 254
           +TGP VV++VTG DV    LGG   H +KSG  H++   + +     +RL+         
Sbjct: 159 VTGPDVVRSVTGEDVDMASLGGPETHHKKSGVCHIVANDELDAYERGRRLVGLFCQQGHF 218

Query: 255 KPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYFAPN 314
              + +  D        +  ++P+   +AYDV  V+ AI+D     N  F E Q  +AP+
Sbjct: 219 DRSKAEAGDT------NIQALLPESSRRAYDVHPVVTAILDE----NTPFDEFQANWAPS 268

Query: 315 AVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPGYLP 374
            V+G GR++G+TVG++ANNP+ L G L+ +S++K ARFVR CDAF IP+V  VDVPGYLP
Sbjct: 269 MVVGLGRLSGRTVGVLANNPLRLGGCLNSESAEKAARFVRLCDAFGIPLVVIVDVPGYLP 328

Query: 375 GVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAWPTAE 434
           GVDQE  G++R GAK+L+A+ E TVP VT++ RK YGGAY+AM S+ L A  VFAWP AE
Sbjct: 329 GVDQEWGGVVRRGAKLLHAFGECTVPRVTLVTRKTYGGAYIAMNSRSLNATKVFAWPDAE 388

Query: 435 IAVMGPEGAANIIFRKEIAKAENPE-EFRKQKIQEYREKFANPYVAA-SRGYIDDVIDPA 492
           +AVMG + A  I+ ++++A A N E E     +    E+ A    +A   G +D+ I+PA
Sbjct: 389 VAVMGAKAAVGILHKRKLAAAPNDEREALHDDLAAEHERIAGGVDSAIDIGVVDEKINPA 448

Query: 493 ETRAKIVMALEALENKRVKLPPKKHGNIPL 522
            TR+K+  AL     +R      +H NIPL
Sbjct: 449 HTRSKLTEALAQSPVRR-----GRHKNIPL 473


>pir||B69893 propionyl-CoA carboxylase homolog yngE - Bacillus subtilis
           >gi|2634204|emb|CAB13704.1| (Z99113) similar to
           propionyl-CoA carboxylase [Bacillus subtilis]
           Length = 595
           
 Score =  343 bits (871), Expect = 3e-93
 Identities = 205/526 (38%), Positives = 294/526 (54%), Gaps = 22/526 (4%)

Query: 3   MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRAT 62
           +M+  ++  +R ++I + G E+  +   +KGKL  RER+ LL D    +E   F +  + 
Sbjct: 86  LMDYEKERTERAERIRKGGAEKYHQSNREKGKLFVRERLSLLFDDDIELEDAFFAECMSD 145

Query: 63  EFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGA 122
                   LPADGV+T  G I G+ V V A D TV  GS G     KI RI E+A +   
Sbjct: 146 -------GLPADGVVTAIGKIGGQTVCVMANDSTVKAGSWGAKTVEKIIRIQEIAEKLNC 198

Query: 123 PVIGLNDSGGARIQEGVDSL---KGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAI 179
           P+I L DS GARI + ++     +G G IF     LSG +PQI  + GP A G  Y PA 
Sbjct: 199 PLIYLVDSAGARITDQINVFPGRRGAGRIFYNQVKLSGRIPQICLLFGPSAAGGAYIPAF 258

Query: 180 GDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIG 239
            D ++MVD  ++ M++  P++ + V G  V+  ++GGA +H   SG   ++ +++EE I 
Sbjct: 259 CDIVVMVDGNAS-MYLGSPRMAEMVIGEKVSLEEMGGARMHCSISGCGDILAETEEEAIQ 317

Query: 240 LIKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDEN 299
           L++  LSY P+N  EK P  + +      TP L D++P + N  +D+ ++I  ++D D  
Sbjct: 318 LVRAYLSYFPANFQEKAPIHEKRPPKHFETP-LADVIPQNQNAPFDMHELIERVIDEDS- 375

Query: 300 GNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAF 359
               F E++  FAP  + G  RI+GQ VGIVAN P    GVL  DS+DK A+F+  CDAF
Sbjct: 376 ----FFEIKALFAPELLTGLARIHGQPVGIVANQPKVKGGVLFHDSADKAAKFITLCDAF 431

Query: 360 NIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGS 419
           +IP++   D+PG++ G   E  GIIRHGAK++ A +EATVP ++VI+RKAYG    AM  
Sbjct: 432 HIPLLFLADIPGFMIGTKVEQAGIIRHGAKMISAMSEATVPKLSVIVRKAYGAGLYAMAG 491

Query: 420 KHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKF---ANP 476
                D   A PTA+IAVMGPE A N ++ K+I  AE PEE R   I   RE++    N 
Sbjct: 492 PAFEPDCCLALPTAQIAVMGPEAAVNAVYAKKI--AELPEEERAAFISSKREEYKEDINI 549

Query: 477 YVAASRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           Y  AS   ID VI     R ++   L+A   K +    +KH   P+
Sbjct: 550 YRLASEMIIDAVIPANSLRDELAKRLKAYMTKEMTFTNRKHPVYPV 595


>dbj|BAB04855.1| (AP001511) propionyl-CoA carboxylase [Bacillus halodurans]
           Length = 504
           
 Score =  341 bits (866), Expect = 1e-92
 Identities = 200/514 (38%), Positives = 290/514 (55%), Gaps = 22/514 (4%)

Query: 15  KKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGMDKRDLPAD 74
           +K+ + G E+  +    KGKL AR+R+ELL D G   E G+F   +          LPAD
Sbjct: 7   EKLKRGGSEKYHEANQQKGKLFARKRLELLFDDGLAAEDGLFANCQVD-------GLPAD 59

Query: 75  GVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGAR 134
           GVITG G ING+ V V A D TV  GS G     KI RI E A +   P++ L DS GAR
Sbjct: 60  GVITGIGKINGQTVCVMANDSTVKAGSWGARTVEKIIRIQETAEKLNVPMLYLVDSAGAR 119

Query: 135 IQEGVDSL---KGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVDNPST 191
           I + V+     +G G IF     LSG VPQ+  + GP A G  Y PA  D ++MVD  ++
Sbjct: 120 ITDQVEMFPGRRGAGRIFYNQVKLSGRVPQVCILFGPSAAGGAYIPAFCDVVIMVDGNAS 179

Query: 192 FMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSN 251
            M++  P++ + V G  V+  ++GGA +H   SG   ++  S+EE IGL +  L Y PS+
Sbjct: 180 -MYLGSPRMAEMVIGEKVSLEEMGGAKMHCSVSGCGDILAPSEEEAIGLARDYLRYFPSS 238

Query: 252 NMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYF 311
             ++PP ++   EP   T  + +I+P + N  +++  +I  ++D D      F E++  F
Sbjct: 239 YSKRPP-IEDGREPKSFTKTIEEILPKNQNAPFNMYDLIDRVIDEDS-----FFEIKKLF 292

Query: 312 APNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPG 371
           AP  + G  RI+G+ +GI+AN P    GVL  DS+DK A+F+  CDA++IP++   D+PG
Sbjct: 293 APELITGLARIDGKPIGIIANQPKMKGGVLFHDSADKAAKFITLCDAYHIPLLFLADIPG 352

Query: 372 YLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAWP 431
           ++ G   E  GIIRHGAK++ A +EATVP +++I+RKAYG    AM       D   A+P
Sbjct: 353 FMIGTKVERAGIIRHGAKMISAMSEATVPKISIIVRKAYGAGLYAMAGPAFEPDVCLAFP 412

Query: 432 TAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKF---ANPYVAASRGYIDDV 488
            A+IAVMGPE A N ++  +I  AE PEE R   I E RE++    + Y  AS   ID +
Sbjct: 413 NAQIAVMGPEAAVNAVYANKI--AELPEEERAAFIAEKREEYKQDIDVYRLASELVIDGI 470

Query: 489 IDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           I   + R ++   L A  +K +    +KH   P+
Sbjct: 471 IQGNQLREELKTRLTAYASKELTFTTRKHPVYPV 504


>gb|AAG19127.1| (AE005010) propionyl-CoA carboxylase homolog; YngE [Halobacterium
           sp. NRC-1]
           Length = 591
           
 Score =  332 bits (841), Expect = 8e-90
 Identities = 195/539 (36%), Positives = 292/539 (53%), Gaps = 27/539 (5%)

Query: 1   MGMMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERI------------ELLLDPG 48
           +G  E+ E L +    IL  G E+  ++  ++ KL  R+R+            +LL + G
Sbjct: 60  LGPTEREEVLREEIADILDGGPEKYKQRLPEQDKLFVRDRLALWFGDDDDGDDDLLFEDG 119

Query: 49  SFVEI-GMFVKHRATEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHA 107
            F    G        +   D   +PADG+ITG    +GR +   A DFTV  GS+ E   
Sbjct: 120 RFAHFDGWHPNSPDVDEADDGTRVPADGLITGAADFDGRDLHFMANDFTVKAGSMAERGV 179

Query: 108 MKIKRIMELALEAGAPVIGLNDSGGARIQEGVD---SLKGYGEIFKMNTILSGVVPQITA 164
            K  R+ + AL+ G PV+ L DS G RI +      + +G G+ +  ++ LSG VPQI  
Sbjct: 180 EKFLRMQQRALKTGKPVLYLMDSSGGRIDQQSGFFANREGIGKYYFNHSRLSGRVPQICV 239

Query: 165 IMGPCAGGAVYSPAIGDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKS 224
           + GPC  GA Y+P   DF +MV+  S  M I  P++V+ VTG  +    LGG  VHA++S
Sbjct: 240 LYGPCIAGAAYTPVFADFTIMVEGMSA-MAIASPRMVEMVTGEQIEMQDLGGPQVHAEQS 298

Query: 225 GQAHLIGKSDEEVIGLIKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAY 284
           G A L+ + ++    L+  L+ YLP N+ EKPP  +P   P +    +  ++P+ PN+AY
Sbjct: 299 GSADLVARDEDHARELVADLVQYLPDNSDEKPPS-QPAKPPAKPPKGIDGLIPEAPNRAY 357

Query: 285 DVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDID 344
           D+  +I  +VD+D      F EL+P +    + G+ RI+G+TVGIVAN P   AG +  D
Sbjct: 358 DMHDLIGRVVDQDS-----FFELRPEYGAEILTGYARIDGRTVGIVANQPAQRAGAIFPD 412

Query: 345 SSDKIARFVRFCDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTV 404
           +++K A FV   DA+NIP++   D PG++PG   E   I+  G K++YA +EATVP  +V
Sbjct: 413 AAEKAAEFVWKSDAYNIPLLYLCDTPGFMPGSSVEKDAILEKGKKMIYATSEATVPKQSV 472

Query: 405 ILRKAYGGAYLAMGSKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQ 464
           ++RKAYG    AM       +   A P+ EI +MGPE A N ++  ++   ++PEE RKQ
Sbjct: 473 VVRKAYGAGIYAMSGPAYDPESTIALPSGEIGIMGPEAAINAVYANKLDAIDDPEE-RKQ 531

Query: 465 KIQEYREKFANPYVA---ASRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNI 520
           + QE RE +     A   AS   ID+++ P+E R ++       E+     P KKHG I
Sbjct: 532 REQELREAYREDIDAHRMASETVIDEIVPPSELRTELSNRFSFYEDVEKDRPSKKHGTI 590


>gb|AAF32341.1|AF218939_9 (AF218939) b-propionyl-CoA carboxylase [Bacillus subtilis]
           Length = 509
           
 Score =  329 bits (835), Expect = 4e-89
 Identities = 200/525 (38%), Positives = 289/525 (54%), Gaps = 22/525 (4%)

Query: 4   MEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATE 63
           M+  ++  +R ++I + G E+  +   +KGKL  RER+ LL D    +E   F +  +  
Sbjct: 1   MDYEKERTERAERIQKGGAEKYHRSNQEKGKLFVRERLALLFDDDIELEDAFFAECMSD- 59

Query: 64  FGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAP 123
                  LPADGV+T  G I G+ V   A D TV  GS G     KI RI E A +   P
Sbjct: 60  ------GLPADGVVTAIGKIGGQTVCAMANDSTVKAGSWGAKTVEKIIRIQETAEKLNCP 113

Query: 124 VIGLNDSGGARIQEGVDSL---KGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG 180
           +I L DS GARI + V+     +G G IF     LSG +PQI  + GP A G  Y PA  
Sbjct: 114 LIYLVDSAGARITDQVNVFPGRRGAGRIFYNQVKLSGRIPQICLLFGPSAAGGAYIPAFC 173

Query: 181 DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL 240
           D ++MVD  ++ M++  P++ + V G  V+  ++GGA +H   SG   ++ ++++E I L
Sbjct: 174 DIVVMVDGNAS-MYLGSPRMAEMVIGEKVSLEEMGGARMHCSVSGCGDILAETEQEAIHL 232

Query: 241 IKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENG 300
            +  LSY P+N  E+ P V+ K  P      L D++P + N  +++ ++I  ++D     
Sbjct: 233 ARSYLSYFPANYKERAP-VQEKRPPKPFEIPLSDVIPQNQNAPFNMFELIDRVIDEGS-- 289

Query: 301 NPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN 360
              F E++  FAP  + G  RI+GQ VGI+AN P    GVL  DS+DK A+F+  CDAF+
Sbjct: 290 ---FFEIKALFAPEIITGLARIHGQPVGIIANQPKVKGGVLFHDSADKAAKFITLCDAFH 346

Query: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSK 420
           IP++   D+PG++ G   E  GIIRHGAK++ A +EATVP ++VI+RKAYG    AM   
Sbjct: 347 IPLLFLADIPGFMIGTKVEQAGIIRHGAKMISAMSEATVPKLSVIVRKAYGAGLYAMAGP 406

Query: 421 HLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKF---ANPY 477
               D   A PTA+IAVMGPE A N ++ K+I  +E P+E R Q I   RE++    N Y
Sbjct: 407 AFEPDCCIALPTAQIAVMGPEAAVNAVYAKKI--SELPKEERAQFISSKREEYKEDINIY 464

Query: 478 VAASRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
             AS   ID VI     R ++   L A   K +    +KH   P+
Sbjct: 465 RLASEMIIDAVIPANSLRGELHKRLMAYMTKEITFTNRKHPVYPV 509


>sp|Q06101|PCCB_RHOER PROPIONYL-COA CARBOXYLASE BETA CHAIN (PCCASE) (PROPANOYL-COA:CARBON
           DIOXIDE LIGASE) >gi|484519|pir||JQ1943 propionyl-CoA
           carboxylase (EC 6.4.1.3) beta chain - Rhodococcus sp
           >gi|152059|gb|AAB80770.1| (M95713) propionyl-CoA
           carboxylase beta chain [Rhodococcus erythropolis]
           Length = 476
           
 Score =  327 bits (830), Expect = 2e-88
 Identities = 176/420 (41%), Positives = 255/420 (59%), Gaps = 25/420 (5%)

Query: 40  RIELLLDPGSFVEIGMFVKHRATEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMG 99
           R+E L DPG+ V +             DK      GV+   G I+G     Y  D TVMG
Sbjct: 22  RLENLFDPGTTVPL----------HARDK-----SGVLAASGNIDGVRTIAYCSDATVMG 66

Query: 100 GSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVV 159
           G++G      + + ++ A+E  +P++GL  SGGAR+ EGV++L   G +F+     SG++
Sbjct: 67  GAMGVDGCKHLVKAIDTAIEEESPIVGLWHSGGARLAEGVEALHAVGLVFEAMVRASGLI 126

Query: 160 PQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALV 219
           PQI+ ++G  AGGA Y PA+ D ++M   P   +F+TGP VV++VTG  V  V LGG   
Sbjct: 127 PQISVVLGFAAGGAAYGPALTDVVIMA--PEGRVFVTGPDVVRSVTGEQVDMVSLGGPDT 184

Query: 220 HAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDD 279
           H +KSG AH+    + + +   +RL+S +           +  D   R       ++P  
Sbjct: 185 HTKKSGVAHIAAHDEADALHRARRLVSMMCEQGEFDQRAAELGDSDLRA------MMPAS 238

Query: 280 PNKAYDVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAG 339
             +AYDVR +++ ++D  E G   F ELQ  +A + V GFGR+ G+TVG++ANNP+ L G
Sbjct: 239 AKRAYDVRPIVHEMLDNVE-GESSFEELQGNYARSIVTGFGRMAGRTVGVIANNPLRL-G 296

Query: 340 VLDIDSSDKIARFVRFCDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATV 399
            L+ +S++K ARFVR C+AF +P+V  VDVPGYLPGV  E  G++R GAK+L+A+AEATV
Sbjct: 297 CLNSESAEKAARFVRLCNAFGVPLVVVVDVPGYLPGVSMEWEGVVRRGAKLLHAFAEATV 356

Query: 400 PMVTVILRKAYGGAYLAMGSKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPE 459
           P VTV+ RK YGGAY+AM S+ LGA  VFAWP +E+AVMG + A  I+ ++ +A A + E
Sbjct: 357 PRVTVVTRKIYGGAYIAMNSRALGATAVFAWPNSEVAVMGAKAAVGILHKRALAAAPDDE 416


>sp|P34385|YLP5_CAEEL HYPOTHETICAL 66.5 KD PROTEIN F02A9.5 IN CHROMOSOME III
           >gi|280542|pir||S28313 hypothetical protein F02A9.5 -
           Caenorhabditis elegans >gi|3875448|emb|CAA79618.1|
           (Z19555) predicted using Genefinder~similar to
           Propionyl-CoA carboxylase beta chain, contains
           similarity to Pfam domain: PF01039 (Carboxyl transferase
           domain), Score=826.9, E-value=2.4e-245, N=1~cDNA EST
           EMBL:M89018 comes from this gene~cDNA EST yk9b2.>
           Length = 608
           
 Score =  287 bits (727), Expect = 2e-76
 Identities = 188/527 (35%), Positives = 281/527 (52%), Gaps = 35/527 (6%)

Query: 7   VEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRATEFG 65
           VEDL  +  KI Q GGE+A+K    +GK+ ARERI+ ++D GS F+E      +      
Sbjct: 98  VEDLKAKISKIEQAGGEKAVKLHRSRGKMLARERIDGIVDAGSPFIEFSQLAGYEM---- 153

Query: 66  MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125
             K ++P+ G++TG G ++GR+  + A D TV GG+   +   K  R  E+A E   P I
Sbjct: 154 YGKEEVPSGGILTGVGIVSGRVCVIVANDATVKGGTYYPITVKKHLRAQEIARENKLPCI 213

Query: 126 GLNDSGGARIQEGVDSL---KGYGEIF-KMNTILSGVVPQITAIMGPCAGGAVYSPAIGD 181
            L DSGGA +    D     + +G IF    T+ S  +PQ+  +MG C  G  Y PA+ D
Sbjct: 214 YLVDSGGANLPRQADIFADSQHFGRIFYNQATMSSEGIPQLAVVMGSCTAGGAYVPAMSD 273

Query: 182 FILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLI 241
             ++V    T +F+ GP +VKA TG +++  +LGGA +H  +SG       +D+  + L 
Sbjct: 274 QAIIVKGTGT-VFLGGPPLVKAATGEEISAEELGGADLHCGESGVTDYYAHNDKHALYLA 332

Query: 242 KRLLSYLPSNNMEKPPRVKPK-DEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENG 300
           +  ++ LP   +E+     P  DEP     E+Y IV  +  K YDVR+VI  IVD     
Sbjct: 333 RSCIAGLPP--VEEHMTFNPNADEPLYPAEEIYGIVGSNLKKTYDVREVIARIVDGSR-- 388

Query: 301 NPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN 360
              F E +  +    V GF  I GQ VGI+ANN     GVL  +S+ K + F+  C    
Sbjct: 389 ---FHEFKERYGETLVTGFATIYGQRVGILANN-----GVLFAESAMKGSHFIELCCQRK 440

Query: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSK 420
           IP++   ++ G++ G D E+ GI +HGAK++ A A A VP +TV++  +YG     M  +
Sbjct: 441 IPLLFLQNITGFMVGRDAEAGGIAKHGAKLVTAVACAKVPKITVLVGGSYGAGNYGMCGR 500

Query: 421 HLGADFVFAWPTAEIAVMGPEGAANII--FRKEIAKAENPE-------EFRKQKIQEYRE 471
                +VF WP + I+VMG E AAN++   +KE  K E  +       E RK  ++E  E
Sbjct: 501 GYSPRYVFMWPNSRISVMGGEQAANVLSTVQKEKKKREGADWTDQQDLELRK-PVEEKFE 559

Query: 472 KFANPYVAASRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHG 518
           K  +PY A++R + D VIDP +TR  + +A ++   K   +P  K G
Sbjct: 560 KEGHPYFASARLWDDGVIDPKDTRKVLGLAFQSTLQK--PIPETKFG 604


>emb|CAB87213.1| (AL163641) acetyl/propionyl CoA carboxylase, beta subunit
           [Streptomyces coelicolor A3(2)]
           Length = 538
           
 Score =  283 bits (716), Expect = 4e-75
 Identities = 184/501 (36%), Positives = 266/501 (52%), Gaps = 32/501 (6%)

Query: 21  GGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRATEFGMDKRDLPADGVITG 79
           GGE A  +   +GKL  R+R++ LLDPGS F+E+           G+     PA GVI G
Sbjct: 43  GGERARARHTARGKLLPRDRVDTLLDPGSPFLELAPLAAD-----GLYDGAAPAAGVIAG 97

Query: 80  YGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARI---Q 136
            G ++GR   + A D TV GG+   M   K  R  E+ALE   P + L DSGGA +    
Sbjct: 98  IGRVSGRECVIVANDATVKGGTYYPMTVKKHLRAQEVALENRLPCLYLVDSGGAFLPMQD 157

Query: 137 EGVDSLKGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFMFI 195
           E     + +G IF     +SG  +PQI A++G C  G  Y PA+ D  ++V N  T +F+
Sbjct: 158 EVFPDREHFGRIFYNQARMSGAGIPQIAAVLGSCTAGGAYVPAMSDEAVIVRNQGT-IFL 216

Query: 196 TGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSNNMEK 255
            GP +VKA TG  VT  +LGG  VH++ SG    + + D   + ++++++S LP      
Sbjct: 217 GGPPLVKAATGEVVTAEELGGGEVHSRVSGVTDHLAEDDPHALRIVRQIVSTLPERGA-L 275

Query: 256 PPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYFAPNA 315
           P  V+   EP     +LY +VP D    YDVR+VI  +VD        F E +  +    
Sbjct: 276 PWGVEAAAEPKADPQDLYGVVPVDSRTPYDVREVIARVVDGSR-----FAEFKSEYGQTL 330

Query: 316 VIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPGYLPG 375
           V GF RI+G  VGIVANN     G+L  +S+ K A F+  CD   IP+V   ++ G++ G
Sbjct: 331 VTGFARIHGHPVGIVANN-----GILFSESAQKGAHFIELCDQRGIPLVFLQNISGFMVG 385

Query: 376 VDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAWPTAEI 435
            D E+ GI +HGAK++ A A   VP +TV++  +YG    +M  +     F++ WP A+I
Sbjct: 386 RDYEAGGIAKHGAKMVTAVACTRVPKLTVVVGGSYGAGNYSMCGRAYSPRFLWMWPNAKI 445

Query: 436 AVMGPEGAANIIF---------RKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYID 486
           +VMG E AA+++          R E   AE  E F K  ++   E+  N Y A +R + D
Sbjct: 446 SVMGGEQAASVLATVKRDQLEGRGEEWPAEEEESF-KAPVRAQYERQGNAYYATARLWDD 504

Query: 487 DVIDPAETRAKIVMALEALEN 507
            VI+PA+TR  + +AL A  N
Sbjct: 505 GVIEPADTRQVLGLALTACAN 525


>gb|AAF35258.1|AF059510_1 (AF059510) 3-methylcrotonyl-CoA carboxylase non-biotinylated
           subunit [Arabidopsis thaliana]
           >gi|7021224|gb|AAF35259.1|AF059511_1 (AF059511)
           3-methylcrotonyl-CoA carboxylase nonbiotinylated subunit
           [Arabidopsis thaliana]
           Length = 587
           
 Score =  277 bits (701), Expect = 2e-73
 Identities = 182/520 (35%), Positives = 265/520 (50%), Gaps = 34/520 (6%)

Query: 7   VEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRATEFG 65
           + +L    KK+L  GGEEA+K+   + KL  RERI+ LLDPGS F+E+     H   E  
Sbjct: 72  LSELRSHIKKVLAGGGEEAVKRNRSRNKLLPRERIDRLLDPGSSFLELSQLAGHELYE-- 129

Query: 66  MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125
                LP+ G+ITG G I+GR+    A D TV GG+   +   K  R  E+A     P I
Sbjct: 130 ---EPLPSGGIITGIGPIHGRICMFMANDPTVKGGTYYPITIKKHLRAQEIAARCRLPCI 186

Query: 126 GLNDSGGARIQEGVDSL---KGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSPAIGD 181
            L DSGGA + +  +     + +G +F   +++S   +PQI  ++G C  G  Y PA+ D
Sbjct: 187 YLVDSGGAYLPKQAEVFPDKENFGRVFYNESVMSSDGIPQIAIVLGSCTAGGAYIPAMAD 246

Query: 182 FILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLI 241
             +MV    T +F+ GP +VKA TG +V+   LGGA VH   SG +    + +   + + 
Sbjct: 247 ESVMVKGNGT-IFLAGPPLVKAATGEEVSAEDLGGATVHCTVSGVSDYFAQDELHGLAIG 305

Query: 242 KRLLSYL---PSNNMEKPPRVKPK--DEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDR 296
           + ++  L       ME     K     EP     EL  I P D  + +DVR +I  IVD 
Sbjct: 306 RNIVKNLHMAAKQGMEGTFGSKNLVYKEPLYDINELRSIAPVDHKQQFDVRSIIARIVDG 365

Query: 297 DENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFC 356
            E     F E +  +    V GF RI GQTVGI+ NN     G+L  +S+ K A F+  C
Sbjct: 366 SE-----FDEFKKQYGTTLVTGFARIYGQTVGIIGNN-----GILFNESALKGAHFIELC 415

Query: 357 DAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLA 416
               IP+V   ++ G++ G   E+ GI + GAK++ A + A VP +T+I   ++G    A
Sbjct: 416 SQRKIPLVFLQNITGFMVGSRAEANGIAKAGAKMVMAVSCAKVPKITIITGASFGAGNYA 475

Query: 417 MGSKHLGADFVFAWPTAEIAVMGPEGAANIIF--------RKEIAKAENPEEFRKQKIQE 468
           M  +    DF+F WP A I +MG   AA ++         R+ I   E  EE  K+K  +
Sbjct: 476 MCGRAYSPDFMFIWPNARIGIMGGAQAAGVLTQIERATKKRQGIKWTEEEEEAFKKKTVD 535

Query: 469 YREKFANPYVAASRGYIDDVIDPAETRAKIVMALEALENK 508
             E+ ANPY + +R + D VIDP +TR  + + L A  N+
Sbjct: 536 AYEREANPYYSTARLWDDGVIDPCDTRKVLGLCLSAALNR 575


>gb|AAG17227.1|AF217984_1 (AF217984) unknown [Homo sapiens]
           Length = 302
           
 Score =  277 bits (701), Expect = 2e-73
 Identities = 142/262 (54%), Positives = 183/262 (69%), Gaps = 6/262 (2%)

Query: 114 MELALEAGAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGA 173
           M+ A+  GAPVIGLNDSGGARIQEGV+SL GY +IF  N   SGV+PQI+ IMGPCAGGA
Sbjct: 1   MDQAITVGAPVIGLNDSGGARIQEGVESLAGYADIFLRNVTASGVIPQISLIMGPCAGGA 60

Query: 174 VYSPAIGDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKS 233
           VYSPA+ DF  MV + S ++FITGP VVK+VT  DVT  +LGGA  H   SG AH   ++
Sbjct: 61  VYSPALTDFTFMVKDTS-YLFITGPDVVKSVTNEDVTQEELGGAKTHTTMSGVAHRAFEN 119

Query: 234 DEEVIGLIKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAI 293
           D + +  ++   +YLP ++ +  P  +  D   R  PEL  IVP +  KAY++  +I+++
Sbjct: 120 DVDALCNLRDFFNYLPLSSQDPAPVRECHDPSDRLVPELDTIVPLESTKAYNMVDIIHSV 179

Query: 294 VDRDENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFV 353
           VD  E     F E+ P +A N ++GF R+NG+TVGIV N P   +G LDI+SS K ARFV
Sbjct: 180 VDERE-----FFEIMPNYAKNIIVGFARMNGRTVGIVGNQPKVASGCLDINSSVKGARFV 234

Query: 354 RFCDAFNIPIVTFVDVPGYLPG 375
           RFCDAFNIP++TFVDVPG+LPG
Sbjct: 235 RFCDAFNIPLITFVDVPGFLPG 256


>pir||F70550 probable accD1 protein - Mycobacterium tuberculosis (strain H37RV)
           >gi|2113935|emb|CAB08920.1| (Z95556) accD1
           [Mycobacterium tuberculosis]
           Length = 529
           
 Score =  276 bits (699), Expect = 4e-73
 Identities = 179/498 (35%), Positives = 268/498 (52%), Gaps = 33/498 (6%)

Query: 20  MGGEEAIKKQH-DKGKLTARERIELLLDPGS-FVEIGMFVKHRATEFGMDKRDLPADGVI 77
           +GG E  +K+H  +GKL  RER++ LLDPGS F+E+           GM   + P  G+I
Sbjct: 32  LGGNERARKRHVSRGKLLPRERVDRLLDPGSPFLELAPLAAG-----GMYGDESPGAGII 86

Query: 78  TGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGA---R 134
           TG G ++GR   + A D TV GG+   M   K  R  E+AL+   P I L DSGGA   R
Sbjct: 87  TGIGRVSGRQCVIVANDATVKGGTYYPMTVKKHLRAQEVALQNMLPCIYLVDSGGAFLPR 146

Query: 135 IQEGVDSLKGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFM 193
             E     + +G IF     +S   +PQ+ A++G C  G  Y PA+ D  ++V    T +
Sbjct: 147 QDEVFPDREHFGRIFYNQATMSAKGIPQVAAVLGSCTAGGAYVPAMSDEAVIVREQGT-I 205

Query: 194 FITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLL-SYLPSNN 252
           F+ GP +VKA TG  V+  +LGG  +H++ SG    +   DE+ + +++ +  ++ P   
Sbjct: 206 FLGGPPLVKAATGEIVSAEELGGGDLHSRTSGVTDHLADDDEDALRIVRAIADTFGPCEP 265

Query: 253 MEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYFA 312
            +    V+   EP     ELYD+VP DP   YDV +V+  IVD  E     F E +  + 
Sbjct: 266 AQWD--VRRSVEPKYPQAELYDVVPPDPRVPYDVHEVVVRIVDGSE-----FSEFKAKYG 318

Query: 313 PNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPGY 372
              V  F R++G  VGIVANN     GVL  +S+ K A F+  CD   IP++   ++ G+
Sbjct: 319 KTLVTAFARVHGHPVGIVANN-----GVLFSESALKGAHFIELCDKRKIPLLFLQNIAGF 373

Query: 373 LPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAWPT 432
           + G D E+ GI +HGAK++ A A A VP +TV++  +YG    +M  +     F++ WP 
Sbjct: 374 MVGRDYEAGGIAKHGAKMVTAVACARVPKLTVVIGGSYGAGNYSMCGRAYSPRFLWMWPN 433

Query: 433 AEIAVMGPEGAANIIFR---KEIAKAENP-----EEFRKQKIQEYREKFANPYVAASRGY 484
           A I+VMG E AA+++     ++++ A  P     EE  K  I+   E   NPY + +R +
Sbjct: 434 ARISVMGGEQAASVLATVRGEQLSAAGTPWSPDEEEAFKAPIRAQYEDQGNPYYSTARLW 493

Query: 485 IDDVIDPAETRAKIVMAL 502
            D +IDPA+TR  + +AL
Sbjct: 494 DDGIIDPADTRTVVGLAL 511


>gi|11545863 non-biotin containing subunit of 3-methylcrotonyl-CoA carboxylase
           [Homo sapiens] >gi|10934059|dbj|BAB16880.1| (AB050049)
           non-biotin containing subunit of 3-methylcrotonyl-CoA
           carboxylase [Homo sapiens]
           Length = 563
           
 Score =  270 bits (682), Expect = 4e-71
 Identities = 179/526 (34%), Positives = 275/526 (52%), Gaps = 37/526 (7%)

Query: 3   MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRA 61
           M   V  L++R + I   GGE+A      +GKL  RERI+ L+DPGS F+E+  F  ++ 
Sbjct: 49  MKALVNQLHERVEHIKLGGGEKARALHISRGKLLPRERIDNLIDPGSPFLELSQFAGYQL 108

Query: 62  TEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAG 121
                D  ++P  G+ITG G ++G    + A D TV GG+   +   K  R  E+A++  
Sbjct: 109 ----YDNEEVPGGGIITGIGRVSGVECMIIANDATVKGGAYYPVTVKKQLRAQEIAMQNR 164

Query: 122 APVIGLNDSGGARIQEGVDSLKG---YGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSP 177
            P I L DSGGA +    D       +G  F    I+S   + QI  +MG C  G  Y P
Sbjct: 165 LPCIYLVDSGGAYLPRQADVFPDRDHFGRTFYNQAIMSSKNIAQIAVVMGSCTAGGAYVP 224

Query: 178 AIGDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEV 237
           A+ D  ++V    T +F+ GP +VKA TG +V+   LGGA +H +KSG +      D   
Sbjct: 225 AMADENIIVRKQGT-IFLAGPPLVKAATGEEVSAEDLGGADLHCRKSGVSDHWALDDHHA 283

Query: 238 IGLIKRLLSYLPSNNMEKP--PRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVD 295
           + L ++++  L   N +K     ++P +EP     ELY IV  +  +++DVR+VI  IVD
Sbjct: 284 LHLTRKVVRNL---NYQKKLDVTIEPSEEPLFPADELYGIVGANLKRSFDVREVIARIVD 340

Query: 296 RDENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRF 355
                   F E + ++    V GF RI G  VGIV NN     GVL  +S+ K   FV+ 
Sbjct: 341 GSR-----FTEFKAFYGDTLVTGFARIFGYPVGIVGNN-----GVLFSESAKKGTHFVQL 390

Query: 356 CDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYL 415
           C   NIP++   ++ G++ G + E+ GI + GAK++ A A A VP +T+I+  +YG    
Sbjct: 391 CCQRNIPLLFLQNITGFMVGREYEAEGIAKDGAKMVAAVACAQVPKITLIIGGSYGAGNY 450

Query: 416 AMGSKHLGADFVFAWPTAEIAVMGPEGAANIIFR----------KEIAKAENPEEFRKQK 465
            M  +     F++ WP A I+VMG E AAN++            K+ + A+  E   K+ 
Sbjct: 451 GMCGRAYSPRFLYIWPNARISVMGGEQAANVLATITKDQRAREGKQFSSAD--EAALKEP 508

Query: 466 IQEYREKFANPYVAASRGYIDDVIDPAETRAKIVMALEALENKRVK 511
           I +  E+  NPY +++R + D +IDPA+TR  + ++  A  N  ++
Sbjct: 509 IIKKFEEEGNPYYSSARVWDDGIIDPADTRLVLGLSFSAALNAPIE 554


>gb|AAC38045.1| (U94697) propionyl-CoA carboxylase beta chain homolog [Caulobacter
           crescentus] >gi|6502513|gb|AAF14341.1|U86303_2 (U86303)
           propionyl-CoA carboxylase beta chain [Caulobacter
           crescentus]
           Length = 211
           
 Score =  269 bits (681), Expect = 5e-71
 Identities = 136/212 (64%), Positives = 164/212 (77%), Gaps = 4/212 (1%)

Query: 311 FAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVP 370
           +A N + GF R++G+TVGIVAN P  LAGVLDIDSS K ARFVRFCDAFNIPIVTFVDVP
Sbjct: 4   WAKNIICGFARMDGETVGIVANQPQVLAGVLDIDSSRKAARFVRFCDAFNIPIVTFVDVP 63

Query: 371 GYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAW 430
           G++PG  QE  G+I+HGAK+L+AY EATVP +TVI RKAYGGAY  M SKHL  D  +AW
Sbjct: 64  GFMPGTKQEYGGLIKHGAKLLFAYTEATVPKITVITRKAYGGAYDVMSSKHLRGDLNYAW 123

Query: 431 PTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYIDDVID 490
           PTAEIAVMG +GA  IIFR+E   A++PE    ++  EY+++FANP+VAA RGYIDDVI 
Sbjct: 124 PTAEIAVMGAKGAVEIIFRQE---AKDPEALAARE-AEYKDRFANPFVAAQRGYIDDVIM 179

Query: 491 PAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
           P  TR +IV  L++L+ K +  P KKH NIPL
Sbjct: 180 PHGTRRRIVRGLKSLKGKELSNPWKKHDNIPL 211


>gb|AAF57388.1| (AE003789) CG3267 gene product [Drosophila melanogaster]
           Length = 578
           
 Score =  266 bits (674), Expect = 3e-70
 Identities = 185/533 (34%), Positives = 268/533 (49%), Gaps = 43/533 (8%)

Query: 3   MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRA 61
           M   V DL     ++L+ GG++AI++   +GKL ARERI LLLD GS F+E+     H  
Sbjct: 48  MASLVGDLRNFTSQVLKGGGQKAIERHTSRGKLLARERINLLLDKGSPFLELSALAGHEL 107

Query: 62  TEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAG 121
                 +  + + G++TG G + G    V A D TV GGS   +   K  R  E+A E  
Sbjct: 108 ----YGEEVVNSGGIVTGVGRVCGTECLVVANDATVKGGSYYPITVKKHLRAQEIAQENR 163

Query: 122 APVIGLNDSGGARIQEGVDSLKG---YGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSP 177
            P I L DSGGA +    D       +G IF     +S   +PQI  +MG C  G  Y P
Sbjct: 164 LPCIYLVDSGGANLPRQADVFPDKLHFGRIFYNQANMSAQGIPQIAVVMGSCTAGGAYVP 223

Query: 178 AIGDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEV 237
           A+ D  ++V    T +F+ GP +VKA TG +V+   LGGA +H + SG        DE  
Sbjct: 224 AMADESIIVKKQGT-IFLAGPPLVKAATGEEVSAEDLGGADLHCKTSGVTDHYALDDEHA 282

Query: 238 IGLIKRLLSYLPSN---------------NMEKPPRVKPKDEPFRRTPELYDIVPDDPNK 282
           + L ++++S L  +               N +        +EP     ELY IV  +  K
Sbjct: 283 LYLARQIVSNLNLSATNSYNDQLMHSSQVNFQTATPPSAVEEPRYDAEELYGIVGPNLTK 342

Query: 283 AYDVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLD 342
           ++DVR+VI  IVD        F E +  +    V GF ++ G TVGIV NN     GVL 
Sbjct: 343 SFDVREVIARIVDGSR-----FTEFKKLYGETLVCGFAKLYGHTVGIVGNN-----GVLF 392

Query: 343 IDSSDKIARFVRFCDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMV 402
            +S+ K A F++ C    IP+V   ++ G++ G D E+ GI ++GAK++ A A A VP  
Sbjct: 393 SESALKGAHFIQLCAQRKIPLVFLQNITGFMVGRDAEANGIAKNGAKMVTAVACANVPKF 452

Query: 403 TVILRKAYGGAYLAMGSKHLGADFVFAWPTAEIAVMGPEGAANIIF------RKEIAKAE 456
           TVI+  +YG     M  +     F++ WP + I+VMG   AAN++       RK   K  
Sbjct: 453 TVIIGGSYGAGNYGMCGRAYSPRFLYMWPNSRISVMGGTQAANVMAQITEDQRKRAGKEF 512

Query: 457 NPEEFRKQK--IQEYREKFANPYVAASRGYIDDVIDPAETRAKIVMALEALEN 507
           + EE +K K  I E  E   +PY + +R + D +IDPA TR  + ++L+A  N
Sbjct: 513 SEEEAQKLKAPIVEMFEAEGSPYYSTARLWDDGIIDPANTRQILGLSLKAALN 565


>pir||F75382 probable propionyl-CoA carboxylase, beta subunit - Deinococcus
           radiodurans (strain R1)
           >gi|6459304|gb|AAF11105.1|AE001998_2 (AE001998)
           propionyl-CoA carboxylase, beta subunit, putative
           [Deinococcus radiodurans]
           Length = 558
           
 Score =  264 bits (667), Expect = 2e-69
 Identities = 177/517 (34%), Positives = 261/517 (50%), Gaps = 46/517 (8%)

Query: 21  GGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRATEFGMDKRDLPADGVITG 79
           GG +A ++QHDKG+LTARER+  L+DPG+ F E+  F  +   E   D    P+ G +TG
Sbjct: 38  GGAKAQQRQHDKGRLTARERVSKLIDPGTPFDELMTFAGYGMYE---DVGGCPSGGTVTG 94

Query: 80  YGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARI---Q 136
            G I GR   + A D TV  G+   + A K+ R   +ALE   P   L DS G  +    
Sbjct: 95  IGQIGGRPWMIIANDATVKAGAFFPITAKKVIRAQTIALENHLPTAYLVDSAGVYLPMQD 154

Query: 137 EGVDSLKGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFMFI 195
           E       +G +F +N  +S   +PQI AIMG C  G  Y P + D ++M +     +++
Sbjct: 155 EIFPDQDDFGRVFYLNARMSAAGIPQIAAIMGNCVAGGAYLPVMCDTLIMTEGSG--LYL 212

Query: 196 TGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLS-YLPSNNME 254
            GP +VKA  G  V    LGGA +H+  +G      K D+  I  ++ L   Y P+    
Sbjct: 213 AGPALVKAAIGQVVDSEDLGGASMHSAIAGTVDYKEKDDDAAINRLRALAELYAPAEPAP 272

Query: 255 KPPRVKP-KDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYFAP 313
              R K  +D P R   +L ++V  D  K YDVR +I ++ D  E     F E +P +  
Sbjct: 273 FAKRRKETQDAPAR---DLTELVGFDSAKTYDVRDLIKSLADGGE-----FHEFKPEYGE 324

Query: 314 NAVIGFGRINGQTVGIVANNP------------------IHLAGVLDIDSSDKIARFVRF 355
             V GF R  G  V  VAN                    I + GV+  DS+DK ARF+  
Sbjct: 325 TIVCGFARAGGYPVAFVANQRTVIKKKLKSGGEPGLRTRIEVGGVIYGDSADKAARFILD 384

Query: 356 CDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYL 415
            +   +P+V   DV G++ G D E  GIIR GAK++ A + + VP +T+I   ++G    
Sbjct: 385 ANQAGVPLVFLSDVTGFMVGRDSEQEGIIRRGAKLVNAVSNSVVPKITIITGGSFGAGNY 444

Query: 416 AMGSKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKA-----ENPEEFRKQKIQEYR 470
           AM  K  G  F+FAWP+A+ AVM    AA  +   ++A       E  +E   +   E +
Sbjct: 445 AMNGKAYGPRFIFAWPSAKYAVMSGNAAAKTLLDIQLAALKRSGHEPDDEELTRLYDEVK 504

Query: 471 EKF---ANPYVAASRGYIDDVIDPAETRAKIVMALEA 504
            K+    +P  AA+R ++D++I+P +TRA+++ ALEA
Sbjct: 505 SKYDTELDPRYAAARLWVDEIIEPNDTRARLIRALEA 541


>emb|CAA68941.1| (Y07660) B subunit of propionyl-CoA carboxylase [Mycobacterium
           tuberculosis]
           Length = 522
           
 Score =  259 bits (656), Expect = 4e-68
 Identities = 173/492 (35%), Positives = 258/492 (52%), Gaps = 43/492 (8%)

Query: 21  GGEEAIKKQH-DKGKLTARERIELLLDPGS-FVEIGMFVKHRATEFGMDKRDLPADGVIT 78
           G E A K +H  +GKL  RER++ LLDPGS F+E+    + R       +R+ P  G+IT
Sbjct: 15  GNERARKXRHVSRGKLLPRERVDRLLDPGSPFLELAPLGRWRHVR----RRNSPGAGIIT 70

Query: 79  GYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGA----R 134
           G G ++GR   + A D TV GG+   M   K  R  E+AL+   P I L DSGGA    R
Sbjct: 71  GIGRVSGRQCVIVANDATVKGGTYYPMTVKKHLRAQEVALQNMLPCIYLVDSGGAXPDPR 130

Query: 135 IQEGVDSLKGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFM 193
             E     + +G IF     +S   +PQ+ A++G C  G  Y PA+ D  ++V    T +
Sbjct: 131 QDEVFPDREHFGRIFYNQATMSAKGIPQVAAVLGSCTAGGAYVPAMSDEAVIVREQGT-I 189

Query: 194 FITGPQVVKAVTGVDVTPVQ-LGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSNN 252
           F+ GP +VKA    ++   + LGG  +H++ SG    +   DE+ + +++ +        
Sbjct: 190 FLGGPPLVKAPARXEIVSAEELGGGDLHSRTSGVTDHLADDDEDALRIVRAIADTF---- 245

Query: 253 MEKPPRVKPKD-EPFRRTP-----ELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLE 306
             +P R +P    PF R P     ELYD+VP DP   YDV +V+  IVD  E     F E
Sbjct: 246 --RPVRTRPMGCAPFGRWPKYPQAELYDVVPPDPRVPYDVHEVVVRIVDGSE-----FSE 298

Query: 307 LQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTF 366
            +  +    V  F R++G  VGIVANN     GVL  +S+ K A F+  CD   IP++  
Sbjct: 299 FKAKYGKTLVTAFARVHGHPVGIVANN-----GVLFSESALKGAHFIELCDKRKIPLLFL 353

Query: 367 VDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADF 426
            ++ G++ G D E+ GI +HGAK++ A A A VP +TV++  +YG    +M  +     F
Sbjct: 354 QNIAGFMVGRDYEAGGIAKHGAKMVTAVACARVPKLTVVIGGSYGAGNYSMCGRAYSPRF 413

Query: 427 VFAWPTAEIAVMGPEGAANIIFR---KEIAKAENP-----EEFRKQKIQEYREKFANPYV 478
           ++ WP A I+VMG E AA+++     ++++ A  P     EE  K  I+   E   NPY 
Sbjct: 414 LWMWPNARISVMGGEQAASVLATVRGEQLSAAGTPWSPDEEEAFKAPIRAQYEDQGNPYY 473

Query: 479 AASRGYIDDVID 490
           + +R + D +ID
Sbjct: 474 STARLWDDGIID 485


>pir||C83395 probable acyl-CoA carboxyltransferase beta chain PA2014 [imported]
           - Pseudomonas aeruginosa (strain PAO1)
           >gi|9948017|gb|AAG05402.1|AE004627_10 (AE004627)
           probable acyl-CoA carboxyltransferase beta chain
           [Pseudomonas aeruginosa]
           Length = 535
           
 Score =  255 bits (645), Expect = 8e-67
 Identities = 174/522 (33%), Positives = 264/522 (50%), Gaps = 30/522 (5%)

Query: 3   MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRA 61
           M+E+V  L     +I + GG  A  +   +GKL  RERI  LLDPGS F+E+     H  
Sbjct: 22  MLEQVNALRTLLGRIHEGGGSAAQARHSARGKLLVRERINRLLDPGSPFLELSALAAHEV 81

Query: 62  TEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAG 121
             +G    ++ A G++ G G + G    +   D TV GG+   +   K  R   +ALE  
Sbjct: 82  --YG---EEVAAAGIVAGIGRVEGVECMIVGNDATVKGGTYYPLTVKKHLRAQAIALENR 136

Query: 122 APVIGLNDSGGARI---QEGVDSLKGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSP 177
            P I L DSGGA +    E     + +G IF     +S   +PQI  +MG C  G  Y P
Sbjct: 137 LPCIYLVDSGGANLPRQDEVFPDREHFGRIFFNQANMSARGIPQIAVVMGSCTAGGAYVP 196

Query: 178 AIGDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEV 237
           A+ D  +MV   +T +F+ GP +VKA TG  V+  +LGGA VH + SG A    + D+  
Sbjct: 197 AMSDETVMVREQAT-IFLAGPPLVKAATGEVVSAEELGGADVHCKVSGVADHYAEDDDHA 255

Query: 238 IGLIKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRD 297
           + + +R ++ L      +     P+  P     ELY ++P D  + YDVR+VI  +VD  
Sbjct: 256 LAIARRCVANLNWRKQGQLQCRAPR-APLYPAEELYGVIPADSKQPYDVREVIARLVDGS 314

Query: 298 ENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCD 357
           E     F E +  F    V GF  ++G  + I+ANN     G+L  +++ K A F+    
Sbjct: 315 E-----FDEFKALFGTTLVCGFAHLHGYPIAILANN-----GILFAEAAQKGAHFIELAC 364

Query: 358 AFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAM 417
              IP++   ++ G++ G   E+ GI +HGAK++ A A A VP  TV++  ++G     M
Sbjct: 365 QRGIPLLFLQNITGFMVGQKYEAGGIAKHGAKLVTAVACARVPKFTVLIGGSFGAGNYGM 424

Query: 418 GSKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAEN-------PEEFR-KQKIQEY 469
             +     F++ WP A I VMG E AA ++ + +  +AE         EE + K  I E 
Sbjct: 425 CGRAYDPRFLWMWPNARIGVMGGEQAAGVLAQVKREQAERAGQQLGVEEEAKIKAPILEQ 484

Query: 470 REKFANPYVAASRGYIDDVIDPAETRAKIVMALEALENKRVK 511
            E   +PY +++R + D VIDPA+TR  + +AL A  N  ++
Sbjct: 485 YEHQGHPYYSSARLWDDGVIDPAQTREVLALALSAALNAPIE 526


>pir||T05433 hypothetical protein F28A23.210 - Arabidopsis thaliana
           >gi|2911059|emb|CAA17569.1| (AL021961) putative protein
           [Arabidopsis thaliana] >gi|7270352|emb|CAB80120.1|
           (AL161584) putative protein [Arabidopsis thaliana]
           Length = 630
           
 Score =  253 bits (640), Expect = 3e-66
 Identities = 182/563 (32%), Positives = 265/563 (46%), Gaps = 77/563 (13%)

Query: 7   VEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRATEFG 65
           + +L    KK+L  GGEEA+K+   + KL  RERI+ LLDPGS F+E+     H   E  
Sbjct: 72  LSELRSHIKKVLAGGGEEAVKRNRSRNKLLPRERIDRLLDPGSSFLELSQLAGHELYE-- 129

Query: 66  MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125
                LP+ G+ITG G I+GR+    A D TV GG+   +   K  R  E+A     P I
Sbjct: 130 ---EPLPSGGIITGIGPIHGRICMFMANDPTVKGGTYYPITIKKHLRAQEIAARCRLPCI 186

Query: 126 GLNDSGGARIQEGVDSL---KGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSPAIGD 181
            L DSGGA + +  +     + +G +F   +++S   +PQI  ++G C  G  Y PA+ D
Sbjct: 187 YLVDSGGAYLPKQAEVFPDKENFGRVFYNESVMSSDGIPQIAIVLGSCTAGGAYIPAMAD 246

Query: 182 FILMVDNPSTFMFITGPQVVK--------------AVTGVDVTPVQLGGALVHAQKSGQA 227
             +MV    T +F+ GP +VK              A TG +V+   LGGA VH   SG +
Sbjct: 247 ESVMVKGNGT-IFLAGPPLVKFLENLTLNEKAFEQAATGEEVSAEDLGGATVHCTVSGVS 305

Query: 228 HLIGKSDEEVIGLIKRLLSYL---PSNNMEKPPRVKPK--DEPFRRTPELYDIVPDDPNK 282
               + +   + + + ++  L       ME     K     EP     EL  I P D  +
Sbjct: 306 DYFAQDELHGLAIGRNIVKNLHMAAKQGMEGTFGSKNLVYKEPLYDINELRSIAPVDHKQ 365

Query: 283 AYDVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLD 342
            +DVR +I  IVD  E     F E +  +    V GF RI GQTVGI+ NN     G+L 
Sbjct: 366 QFDVRSIIARIVDGSE-----FDEFKKQYGTTLVTGFARIYGQTVGIIGNN-----GILF 415

Query: 343 IDSSDKIARFVRFCDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMV 402
            +S+ K A F+  C    IP+V   ++ G++ G   E+ GI + GAK++ A + A VP +
Sbjct: 416 NESALKGAHFIELCSQRKIPLVFLQNITGFMVGSRAEANGIAKAGAKMVMAVSCAKVPKI 475

Query: 403 TVILRKAYGGAYLAMGSKHLGADFVFAWPTAEIAVMG----------------------- 439
           T+I   ++G    AM  +    DF+F WP A I +MG                       
Sbjct: 476 TIITGASFGAGNYAMCGRAYSPDFMFIWPNARIGIMGGAQVNQNAPKCLNRNQTESKCVY 535

Query: 440 ------PEGAANIIF--------RKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYI 485
                    AA ++         R+ I   E  EE  K+K  +  E+ ANPY + +R + 
Sbjct: 536 NLSVAEQNSAAGVLTQIERATKKRQGIKWTEEEEEAFKKKTVDAYEREANPYYSTARLWD 595

Query: 486 DDVIDPAETRAKIVMALEALENK 508
           D VIDP +TR  + + L A  N+
Sbjct: 596 DGVIDPCDTRKVLGLCLSAALNR 618


>pir||D70719 probable propionyl-CoA carboxylase - Mycobacterium tuberculosis
           (strain H37RV) >gi|3261632|emb|CAB02011.1| (Z79700)
           accD2 [Mycobacterium tuberculosis]
           Length = 529
           
 Score =  238 bits (602), Expect = 9e-62
 Identities = 163/520 (31%), Positives = 264/520 (50%), Gaps = 31/520 (5%)

Query: 3   MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRA 61
           M  K++++     K L  GG + + + H +G LT RERIELL+DP S F+E+     + +
Sbjct: 20  MSGKLDEINAELAKALAGGGPKYVDRHHARGNLTPRERIELLVDPDSPFLELSPLAAYGS 79

Query: 62  T-EFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA 120
             + G          ++TG G + G    + A D TV GG+       KI R  ++A E 
Sbjct: 80  NFQIGAS--------LVTGIGAVCGVECMIVANDPTVKGGTSNPWTLRKILRANQIAFEN 131

Query: 121 GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSPAI 179
             PVI L +SGGA +    +     G++F+  T LS   +P I  + G    G  Y P +
Sbjct: 132 RLPVISLVESGGADLPTQKEIFIPGGQMFRDLTRLSAAGIPTIALVFGNSTAGGAYVPGM 191

Query: 180 GDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIG 239
            D ++M+   S  +F+ GP +VK  TG +     LGGA +HA+ SG A      + + I 
Sbjct: 192 SDHVVMIKERSK-VFLAGPPLVKMATGEESDDESLGGAEMHARISGLADYFALDELDAIR 250

Query: 240 LIKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDEN 299
           + +R+++ L  N +++ P   P  EP     EL  IVP D    +D R+VI  IVD  E 
Sbjct: 251 IGRRIVARL--NWIKQGPAPAPVTEPLFDAEELIGIVPPDLRIPFDPREVIARIVDGSE- 307

Query: 300 GNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAF 359
               F E +P +  + V G+ R++G  +GI+AN      GVL  + S K  +F++  +  
Sbjct: 308 ----FDEFKPLYGSSLVTGWARLHGYPLGILAN----ARGVLFSEESQKATQFIQLANRA 359

Query: 360 NIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGS 419
           + P++   +  GY+ G D E  G+I+HG+ ++ A + +TVP +++++  +YG  +  M  
Sbjct: 360 DTPLLFLHNTTGYMVGKDYEEGGMIKHGSMMINAVSNSTVPHISLLIGASYGAGHYGMCG 419

Query: 420 KHLGADFVFAWPTAEIAVMGP---EGAANIIFRKEI-AKAENPEE----FRKQKIQEYRE 471
           +     F+FAWP+A+ AVMG     G  +I+ R    A+ +  +E      +  ++   E
Sbjct: 420 RAYDPRFLFAWPSAKSAVMGGAQLSGVLSIVARAAAEARGQQVDEAADAAMRAAVEGQIE 479

Query: 472 KFANPYVAASRGYIDDVIDPAETRAKIVMALEALENKRVK 511
             + P V +   Y D VIDP +TR  + M L A+ N  +K
Sbjct: 480 AESLPLVLSGMLYDDGVIDPRDTRTVLGMCLSAIANGPIK 519


>emb|CAB95891.1| (AL359988) putative acetyl/propionyl CoA carboxylase, beta subunit
           [Streptomyces coelicolor A3(2)]
           Length = 532
           
 Score =  238 bits (600), Expect = 2e-61
 Identities = 163/513 (31%), Positives = 254/513 (48%), Gaps = 29/513 (5%)

Query: 3   MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRA 61
           M+ K+ DL     K L  GGE+ + +   +GKL ARERIELLLDP + F+E+        
Sbjct: 22  MLAKLADLDAEHAKALAGGGEKYVARHRKRGKLLARERIELLLDPDTPFLELSPLAAW-G 80

Query: 62  TEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAG 121
           +E+ +         ++TG G + G    + A D TV GG+       K  R  ++AL   
Sbjct: 81  SEYTVGA------SLVTGIGVVEGVECLITANDPTVRGGASNPWSLKKALRANDIALANR 134

Query: 122 APVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSPAIG 180
            P I L +SGGA +    +     G IF+  T LS   +P I  + G    G  Y P + 
Sbjct: 135 LPCISLVESGGADLPSQKEIFIPGGAIFRDLTRLSAAGIPTIAVVFGNSTAGGAYIPGMS 194

Query: 181 DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL 240
           D  +MV   +  +F+ GP +VK  TG +     LGGA +HA+ SG A      + + +  
Sbjct: 195 DHTIMVKERAK-VFLGGPPLVKMATGEESDDESLGGAEMHARTSGLADHFAVDEPDALRQ 253

Query: 241 IKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENG 300
            +R+++ L        P   P + P     EL  IVP D    +D R+VI  IVD     
Sbjct: 254 ARRVVARLNHRKAYADP--PPAEPPMYDPEELLGIVPGDLRTPFDPREVIARIVDAS--- 308

Query: 301 NPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFN 360
             DF E +P +  +   G+  ++G  VGI+AN      GVL  + S K A+F++  +  +
Sbjct: 309 --DFDEFKPLYGTSLTTGWAALHGYPVGILAN----ARGVLFSEESQKAAQFIQLANQRD 362

Query: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSK 420
           IP++   +  GY+ G + E  GII+HGA ++ A + + VP ++V+L  +YG  +  M  +
Sbjct: 363 IPLLFLHNTTGYMVGREYEQGGIIKHGAMMINAVSNSRVPHLSVLLGASYGAGHYGMCGR 422

Query: 421 HLGADFVFAWPTAEIAVMGPE---GAANIIFRKEIAKAENP-----EEFRKQKIQEYREK 472
                F+FAWP+A+ AVMGP+   G  +I+ R+  A    P     +   +  +++  E 
Sbjct: 423 AYDPRFLFAWPSAKSAVMGPQQLAGVLSIVARQSAAAKGQPYDDEGDAALRAMVEQQIES 482

Query: 473 FANPYVAASRGYIDDVIDPAETRAKIVMALEAL 505
            + P   + R Y D VIDP +TR  + + L A+
Sbjct: 483 ESLPMFLSGRLYDDGVIDPRDTRTVLGLCLSAV 515


>dbj|BAB16296.1| (AB039884) acetyl-CoA carboxylase carboxyltransferase [Myxococcus
           xanthus]
           Length = 538
           
 Score =  238 bits (600), Expect = 2e-61
 Identities = 167/528 (31%), Positives = 262/528 (48%), Gaps = 27/528 (5%)

Query: 3   MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRA 61
           M+ +V +L     K+     + A +K H +G+L  RER+ LLLD GS F+E+     +  
Sbjct: 22  MLARVSELRAIEAKVRNTENQ-AKEKFHKRGQLLPRERLMLLLDRGSPFLELSTLCGYGY 80

Query: 62  TEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAG 121
            +       L     I G G ++G    V+  +  + GG+       K  R   LALE  
Sbjct: 81  HDDS--DGSLAGGNSIIGIGYVSGVRCIVFVNNSAIKGGTASPWGVQKALRAQALALENK 138

Query: 122 APVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSPAIG 180
            P++ L +SGGA +    +     GE F     LS   +PQ+T + G    G  Y P + 
Sbjct: 139 LPMVSLVESGGANLMYQQEIFIPGGETFYNQARLSAAGIPQVTVVHGSSTAGGAYLPGLS 198

Query: 181 DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL 240
           D+++MV   +  +F+ GP ++KA TG   T  +LGGA +HA  +G A  + + D + I +
Sbjct: 199 DYVVMVKKKAK-VFLAGPPLLKAATGEVATDEELGGAQMHATVAGTADYLAEDDADAIRM 257

Query: 241 IKRLLSYLPSNNMEKPPRVKPK-DEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDEN 299
            + +++ L   N + PP  +P   EP     EL   VP D  K YD R+VI  IVD  E 
Sbjct: 258 AREIVAKL-GWNAQLPPTERPAYAEPVYSPDELCGAVPVDYRKPYDCREVIARIVDGSE- 315

Query: 300 GNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAF 359
               F   +  +  + V G+  + G  +GI+ NN     G +    + K A+F++ C   
Sbjct: 316 ----FTGFKDEYDAHTVCGWANLYGHPLGIIGNN-----GPISPQGATKAAQFIQLCCQK 366

Query: 360 NIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGS 419
           + PI+   +  GYL G   E  GI++HGAK++ A A ATVP +TV++  A+G     M  
Sbjct: 367 DTPILYLQNTTGYLVGTQPEQGGIVKHGAKMIQAVANATVPQLTVLIGGAFGAGNYGMCG 426

Query: 420 KHLGADFVFAWPTAEIAVMGPEGAA---NIIFRKEIAKAEN--PEEFRK---QKIQEYRE 471
           +     F+F WP +  AVMG E AA   +I+F +++A+      EE  K   Q I +  +
Sbjct: 427 RPFHPRFIFGWPNSRTAVMGGEQAAKVMSIVFGEKLARQGQVVDEEQLKAFCQPIIDQFD 486

Query: 472 KFANPYVAASRGYIDDVIDPAETRAKIVMALEAL-ENKRVKLPPKKHG 518
           K ++P+  ++R + D +IDP +TR  +  AL    E KR ++ P   G
Sbjct: 487 KESHPFNCSARMFDDGLIDPRDTRRVLGFALSVCREAKRRQVHPNTFG 534


>pir||C83284 probable biotin-dependent carboxylase PA2888 [imported] -
           Pseudomonas aeruginosa (strain PAO1)
           >gi|9948979|gb|AAG06276.1|AE004715_2 (AE004715) probable
           biotin-dependent carboxylase [Pseudomonas aeruginosa]
           Length = 538
           
 Score =  235 bits (592), Expect = 1e-60
 Identities = 140/448 (31%), Positives = 229/448 (50%), Gaps = 18/448 (4%)

Query: 3   MMEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRA 61
           M+  V    +  +K+L    E A  K   +G+L  RER+ LLLDPG+ F+E+     ++ 
Sbjct: 22  MLAAVAGFRELEQKVLDKAAE-ARPKFEKRGQLLPRERLALLLDPGAPFLELSSLAGYKL 80

Query: 62  TEFGMDKRDLPADG-VITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEA 120
            +   DK    A G +I G G I G    V A +  + GG++      K  R+ ++A+E 
Sbjct: 81  HD---DKDGTQAGGGIIAGIGYIAGVRCLVSASNSAIKGGTISPTGLKKTLRLQQIAMEN 137

Query: 121 GAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVYSPAI 179
             PV+ L +SGGA +    +        F     +S + +PQ+T + G    G  Y P +
Sbjct: 138 KLPVVTLTESGGANLNYAAEIFVEGARGFANQARISAMGIPQVTVVHGSSTAGGAYQPGL 197

Query: 180 GDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIG 239
            D++++V   +  MF+ GP ++KA TG   +  +LGGA +HAQ +G A  + ++D + + 
Sbjct: 198 SDYVVVVRGKAK-MFLAGPPLLKAATGEIASDEELGGAELHAQVAGTAEYLAENDADGVR 256

Query: 240 LIKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDEN 299
           L + ++  LP N        +   EP     EL  +VP DP K YDVR+++  I D  E 
Sbjct: 257 LAREIVGMLPWNAQLPARPARSWREPLYPVEELLGVVPADPKKPYDVREIVARIADGSE- 315

Query: 300 GNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAF 359
               FL+ +  F    V G  RI G   G++ NN     G +    + K A+F++ C+  
Sbjct: 316 ----FLDFKNEFDGQTVCGHLRIEGHACGLIGNN-----GPITPQGAAKAAQFIQLCEQS 366

Query: 360 NIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGS 419
           N P++   +  G++ G + E +G+I+HG+K++ A A A VP +T+++  +YG    AM  
Sbjct: 367 NTPLLFLHNTTGFMVGTESERQGVIKHGSKMIQAVANARVPKLTLVVGGSYGAGNYAMCG 426

Query: 420 KHLGADFVFAWPTAEIAVMGPEGAANII 447
           + L   F+FAWP +  AVMG   A  ++
Sbjct: 427 RGLDPRFIFAWPNSRTAVMGGAQAGKVL 454


>pir||B83471 probable pyruvate carboxylase PA1400 [imported] - Pseudomonas
            aeruginosa (strain PAO1)
            >gi|9947346|gb|AAG04789.1|AE004569_7 (AE004569) probable
            pyruvate carboxylase [Pseudomonas aeruginosa]
            Length = 1095
            
 Score =  224 bits (565), Expect = 2e-57
 Identities = 172/524 (32%), Positives = 254/524 (47%), Gaps = 59/524 (11%)

Query: 9    DLYQRRKKILQMGGE---EAIKKQHDKGKLTARERIELLLDPGSFVEIGMFV-----KHR 60
            DL +  ++   +G E   +A+ ++   G+ TARE +  LLD GSF E G F      + R
Sbjct: 581  DLAEVLERQAALGDERRPQALARRRKTGQRTARENVLDLLDEGSFSEYGGFALAAQRRRR 640

Query: 61   ATEFGMDKRDLPADGVITGYGTINGRLV-------FVYAQDFTVMGGSLGEMHAMKIKRI 113
            + E  ++    PADG++ G GT+             V A D+TV  G+ G M+  K  R+
Sbjct: 641  SAEELLELS--PADGLVAGTGTVGAASFGVQAARCLVLAYDYTVFAGTQGVMNHKKTDRL 698

Query: 114  MELALEAGAPVIGLNDSGGARIQE----GVDSLKGYGEIFKMNTILSGVVPQITAIMGPC 169
            + LA +   P++   + GG R  +    GV  L  +   F     LSG+VP +  + G C
Sbjct: 699  LGLAEQWRLPLVLFAEGGGGRPGDTDFVGVAGLDCH--TFVGMARLSGLVPLVGVVSGRC 756

Query: 170  AGGAVYSPAIGDFILMVDNPSTFMFITGPQVVKA-----VTGVDVTPVQLGGALVHAQKS 224
              G        D I+   + +  M   GP +++          +V P  + G       +
Sbjct: 757  FAGNAALLGCCDVIIATRDATIGM--AGPAMIEGGGLGRFAAEEVGPTGVQGP------N 808

Query: 225  GQAHLIGKSDEEVIGLIKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAY 284
            G   ++ + + E + + +R L Y               D       EL  +VP++  +AY
Sbjct: 809  GVIDVLVEDEAEAVAVARRYLGYFQG---------PLPDWSCADQRELRHLVPENRLRAY 859

Query: 285  DVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVANNPIHLAGVLDID 344
            D+RQ I  + DR        LEL+  FAP  V    RI G+  G++ANNP HL G +D  
Sbjct: 860  DIRQAIEVLADRGS-----VLELRRQFAPGLVTALLRIEGRAFGLIANNPGHLGGAIDAA 914

Query: 345  SSDKIARFVRFCDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTV 404
            + DK ARF++ CDAF+IPIV+  D PG++ G + E +  +RH +++  + A  TVP  TV
Sbjct: 915  AGDKAARFMQLCDAFDIPIVSLCDTPGFMVGPEAEKQATVRHVSRMFVSAASLTVPFFTV 974

Query: 405  ILRKAYG-GAY-LAMGSKHLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEE-- 460
            +LRK YG GA  +A GS H    F  AWP+ E   MG EGA  + F KE+A  E+P+   
Sbjct: 975  VLRKGYGLGAQAMAAGSFH-SPLFTVAWPSGEFGAMGLEGAVRLGFAKELAAEEDPQRRE 1033

Query: 461  --FRKQKIQEYREKFANPYVAASRGYIDDVIDPAETRAKIVMAL 502
              FR    + YR         AS   ID VIDPAETRA ++  L
Sbjct: 1034 ALFRGMVDKAYRN--GKALNMASYLEIDAVIDPAETRAWLLRGL 1075


>pir||C75585 carboxylase - Deinococcus radiodurans (strain R1)
            >gi|6460763|gb|AAF12468.1|AE001863_93 (AE001863)
            carboxylase [Deinococcus radiodurans]
            Length = 1091
            
 Score =  215 bits (542), Expect = 1e-54
 Identities = 161/497 (32%), Positives = 245/497 (48%), Gaps = 41/497 (8%)

Query: 25   AIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGMDKRD-----LPADGVITG 79
            A++K+H  GKLTARE +  LLD GSF E G      A + G    +      PADG+ITG
Sbjct: 599  AVEKRHAAGKLTARENVAALLDAGSFNEHGALAL--AAQRGRRSEEELLALSPADGLITG 656

Query: 80   YGTING------RLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGA 133
             GT+N           V A D+TV+ G+ G  +  K+ R++ LA +   P++   + GG 
Sbjct: 657  VGTVNAGQFPDTAACAVAAYDYTVLAGTQGYFNHHKLDRLIALAGQWKWPLVLFAEGGGG 716

Query: 134  RIQEGVDSLKG--YGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVDNPST 191
            R  +    +        F     LSG VP +    G C  G        D ++   + S 
Sbjct: 717  RPGDTDMPVAAALVTPTFLNFAALSGQVPLVGVAAGACFAGNAALLGCCDVVIATRDSS- 775

Query: 192  FMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSN 251
             + + GP +++      V    +G A V AQK G   L+ ++D E   L +R L+Y   +
Sbjct: 776  -IGLGGPAMIEGGGLGVVAAGDIGPAEVLAQK-GVVDLLAENDAEANELARRYLTYFQGD 833

Query: 252  NMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYF 311
                   V   +   +R  EL  ++P    +AYDVR +++ + D         LEL+  F
Sbjct: 834  -------VTGWEAADQR--ELRWVIPQVRKRAYDVRALLHLLADTGS-----VLELRRAF 879

Query: 312  APNAVIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPG 371
            AP  +    RI G+  G++AN+P  L G +D   +DK ARF+  CD   +P+++ VD PG
Sbjct: 880  APGLLTALVRIGGKAFGVIANDPAVLGGAIDAAGADKAARFLNLCDTHRLPVLSLVDTPG 939

Query: 372  YLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYG-GAY-LAMGSKHLGADFVFA 429
            ++ G   E+ G +RH +++    A+ TVP   V+ R+AYG GA  +A GS H  A    +
Sbjct: 940  FMVGPASEAEGAVRHVSRLFVRAAKLTVPFFAVVTRRAYGLGAQAMAAGSLHAPA-LTVS 998

Query: 430  WPTAEIAVMGPEGAANIIFRKEIAKAENPEE----FRKQKIQEYREKFANPYVAASRGYI 485
            WP  E   MG EGA  + +R+E+A   +P+E    ++K   Q Y +        A+   +
Sbjct: 999  WPGGEFGPMGLEGAVRLGYRRELAAVSDPQEREALYQKLVAQAYAQ--GEAVNVAAHLEV 1056

Query: 486  DDVIDPAETRAKIVMAL 502
            D VIDPAETR  ++ AL
Sbjct: 1057 DAVIDPAETRNWLLRAL 1073


>pir||T45098 probable propionyl-coA carboxylase beta chain [imported] -
           Mycobacterium smegmatis (fragment)
           >gi|2073536|gb|AAC45278.1| (U46844) putative
           propionyl-coA carboxylase beta chain [Mycobacterium
           smegmatis]
           Length = 210
           
 Score =  197 bits (495), Expect = 3e-49
 Identities = 99/209 (47%), Positives = 135/209 (64%), Gaps = 2/209 (0%)

Query: 316 VIGFGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPGYLPG 375
           +  F R++G  VG++AN P+ L+G +D ++SDK A F+RFCD++N+P+V  VD PG +PG
Sbjct: 2   ITAFARVDGHPVGVIANQPMVLSGAIDNEASDKAASFIRFCDSYNLPLVFVVDTPGAMPG 61

Query: 376 VDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAWPTAEI 435
           V +E  GII+ G +   A  EA VP VTVI+RKAYGG Y  MGSK L AD  FAWPTA I
Sbjct: 62  VAEEKGGIIKRGGRFFNAIVEADVPKVTVIIRKAYGGGYAVMGSKQLSADLNFAWPTARI 121

Query: 436 AVMGPEGAANIIFRK-EIAKAENPEEFRKQKIQEYREKFANPYVAASRGYIDDVIDPAET 494
           AV+G EGAA ++ ++     A   ++ R   I+ Y    A P++AA RGYID VI P ET
Sbjct: 122 AVIGAEGAAQLLVKRFPDPNAPEVQKIRDDFIEGYNLNMATPWIAAERGYIDAVIQPHET 181

Query: 495 RAKIVMALEALENKR-VKLPPKKHGNIPL 522
           R  +  +L  L +K+      +KHG +PL
Sbjct: 182 RLLLRKSLRLLRDKQNGPKVQRKHGLLPL 210


>gb|AAC69174.1| (AF030576) methylmalonyl-CoA decarboxylase alpha subunit
           [Acidaminococcus fermentans]
           Length = 154
           
 Score =  194 bits (489), Expect = 2e-48
 Identities = 98/162 (60%), Positives = 119/162 (72%), Gaps = 8/162 (4%)

Query: 361 IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSK 420
           IP++  VDVPG+LPG DQE  GIIRHGAK+LYAY EATVP +T++ RKAYGGAYLAM ++
Sbjct: 1   IPLINIVDVPGFLPGTDQEYGGIIRHGAKMLYAYCEATVPKITLVTRKAYGGAYLAMCAQ 60

Query: 421 HLGADFVFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAA 480
            LGAD V AWPTAEIAVMGP+GAA IIFRK+      P+   +QK QEY   FA PY AA
Sbjct: 61  DLGADHVIAWPTAEIAVMGPQGAAKIIFRKD------PDV--EQKTQEYITNFATPYYAA 112

Query: 481 SRGYIDDVIDPAETRAKIVMALEALENKRVKLPPKKHGNIPL 522
             G ++ VI+P  TR  ++ AL  L++K+   P KKHGNIPL
Sbjct: 113 KHGMVEMVIEPKTTRPILIKALRMLKSKQEDRPTKKHGNIPL 154


>gb|AAA60036.1| (M13573) propionyl-CoA carboxylase beta chain (EC 6.4.1.3) [Homo
           sapiens]
           Length = 155
           
 Score =  185 bits (464), Expect = 1e-45
 Identities = 94/155 (60%), Positives = 114/155 (72%), Gaps = 5/155 (3%)

Query: 263 DEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIGFGRI 322
           D   R  PEL  IVP +  KAY++  +I+++VD  E     F E+ P +A N ++GF R+
Sbjct: 5   DPSDRLVPELDTIVPLESTKAYNMVDIIHSVVDERE-----FFEIMPNYAKNIIVGFARM 59

Query: 323 NGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPGYLPGVDQESRG 382
           NG+TVGIV N P   +G LDI+SS K ARFVRFCDAFNIP++TFVDVPG+LPG  QE  G
Sbjct: 60  NGRTVGIVGNQPKVASGCLDINSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGG 119

Query: 383 IIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAM 417
           IIRHGAK+LYA+AEATVP VTVI RKAYGGAY  M
Sbjct: 120 IIRHGAKLLYAFAEATVPKVTVITRKAYGGAYDVM 154


>emb|CAA74219.1| (Y13917) yngE [Bacillus subtilis]
           Length = 280
           
 Score =  169 bits (423), Expect = 9e-41
 Identities = 102/289 (35%), Positives = 156/289 (53%), Gaps = 12/289 (4%)

Query: 4   MEKVEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATE 63
           M+  ++  +R ++I + G E+  +   +KGKL  RER+ LL D    +E   F +  +  
Sbjct: 1   MDYEKERTERAERIRKGGAEKYHQSNREKGKLFVRERLSLLFDDDIELEDAFFAECMSD- 59

Query: 64  FGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAP 123
                  LPADGV+T  G I G+ V V A D TV  GS G     KI RI E+A +   P
Sbjct: 60  ------GLPADGVVTAIGKIGGQTVCVMANDSTVKAGSWGAKTVEKIIRIQEIAEKLNCP 113

Query: 124 VIGLNDSGGARIQEGVD---SLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIG 180
           +I L DS GARI + ++     +G G IF     LSG +PQI  + GP A G  Y PA  
Sbjct: 114 LIYLVDSAGARITDQINVFPGRRGAGRIFYNQVKLSGRIPQICLLFGPSAAGGAYIPAFC 173

Query: 181 DFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAHLIGKSDEEVIGL 240
           D ++MVD  ++ M++  P++ + V G  V+  ++GGA +H   SG   ++ +++EE I L
Sbjct: 174 DIVVMVDGNAS-MYLGSPRMAEMVIGEKVSLEEMGGARMHCSISGCGDILAETEEEAIQL 232

Query: 241 IKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQV 289
           ++  LSY P+N  EK P +  K  P      L D++P + N  +D+ ++
Sbjct: 233 VRAYLSYFPANFQEKAP-IHEKRPPKHFETPLADVIPQNQNAPFDMHEL 280


>sp|Q06700|GCDA_ACIFE GLUTACONYL-COA DECARBOXYLASE A SUBUNIT (CARBOXYLTRANSFERASE)
           >gi|321991|pir||S29787 UDPgalacturonate decarboxylase
           (EC 4.1.1.67) alpha chain - Acidaminococcus fermentans
           >gi|49182|emb|CAA49210.1| (X69435) Glutaconyl-CoA
           decarboxylase [Acidaminococcus fermentans]
           Length = 587
           
 Score =  128 bits (318), Expect = 2e-28
 Identities = 129/538 (23%), Positives = 220/538 (39%), Gaps = 56/538 (10%)

Query: 8   EDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGSFVEIGMFVKHRATEFGMD 67
           E+++Q  K+  + G  +A    + +G+LTA +RIE L++PGS+  +      +  + G  
Sbjct: 36  EEIHQLIKEAQEAGKADA--DVNKRGELTALQRIEKLVEPGSWRPLNTLFNPQGNKNG-- 91

Query: 68  KRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGL 127
                +  ++ G G +NG+   V A D   + G+     A  + R  + A     P++ +
Sbjct: 92  -----SVAIVKGLGRVNGKWCVVVASDNKKLAGAWVPGQAECLLRASDTAKTLHVPLVYV 146

Query: 128 NDSGGARIQEG---VDSLKGYGEIFKMNTILSGV-VPQITAIMGPCAGGAVY---SPAI- 179
            +  G +  E      + +G G  F  N  L+ + +P I  I G    G  Y   SP + 
Sbjct: 147 LNCSGVKFDEQEKVYPNRRGGGTPFFRNAELNQLGIPVIVGIYGTNPAGGGYHSISPTVI 206

Query: 180 -----------GDFILMVDNPSTFMFITGPQVVKAVTGVDVTPVQLGGALVHAQKSGQAH 228
                      G  I+   NP   + +     +  +          G   +H  ++G   
Sbjct: 207 IAHEKANMAVGGAGIMGGMNPKGHVDLEYANEIADMVDRTGKTEPPGAVDIHYTETGFMR 266

Query: 229 LIGKSDEEVIGLIKRLLSYLPSNNMEKPPRVKPKDEPFRRTPELYDIVPDDPNKAYDVRQ 288
            +  S+E V+  IK+ +  LP  + E   RV     P     +LY +VP +  +AYD+  
Sbjct: 267 EVYASEEGVLEGIKKYVGMLPKYDPEFF-RVDDPKAPAFPADDLYSMVPLNDKRAYDIYN 325

Query: 289 VIYAIVDRDENGNPDFLELQPYFAPNAVIGFGRINGQTVGIVAN--------------NP 334
           VI  + D     N +  E +  + P  V G  ++NG  VG+VAN                
Sbjct: 326 VIARLFD-----NSELHEYKKGYGPEMVTGLAKVNGLLVGVVANVQGLLMNYPEYKAAGS 380

Query: 335 IHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAY 394
           + + G L      K+  FV  C    +PIV   D  G   G D E   ++  G  ++Y+ 
Sbjct: 381 VGIGGKLYRQGLVKMNEFVTLCARDRLPIVWIQDTTGIDVGNDAEKAELLGLGQSLIYSI 440

Query: 395 AEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAWPTA--EIAVMGPEGAANIIFRKEI 452
             + +P   + LRK    A+  +G         F+  TA  EIAVM  E AA  ++ + +
Sbjct: 441 QTSHIPQFEITLRKGTAAAHYVLGGPQGNDTNAFSIGTAATEIAVMNGETAATAMYSRRL 500

Query: 453 AKAENPEEFRKQKIQEYREKF------ANPYVAASRGYIDDVIDPAETRAKIVMALEA 504
           AK     +  +  I +           + P V A  G +D+++D  + R  +    EA
Sbjct: 501 AKDRKAGKDLQPTIDKMNNLIQAFYTKSRPKVCAELGLVDEIVDMNKIRGYVEAFTEA 558


>emb|CAC00930.1| (AL390935) probable propionyl-coa carboxylase beta chain,
           mitochondrial precursor(ec 6.4.1.3) [Leishmania major]
           Length = 106
           
 Score =  108 bits (268), Expect = 1e-22
 Identities = 55/110 (50%), Positives = 71/110 (64%), Gaps = 5/110 (4%)

Query: 259 VKPKDEPFRRTPELYDIVPDDPNKAYDVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIG 318
           V   D  +R    L  +VP +  +AYD+R  I+ ++D+D      F E+QP FA N + G
Sbjct: 2   VPTADNRYRDVSSLNTVVPVEVKEAYDMRDAIFPVIDQDS-----FFEIQPQFAKNIICG 56

Query: 319 FGRINGQTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTFVD 368
           F R+ G++V I+AN P   AGVLDIDSS K AR VRF DAFNIPI+TFVD
Sbjct: 57  FARVEGRSVCIIANQPKVQAGVLDIDSSVKAARMVRFADAFNIPIITFVD 106


>emb|CAA19885.1| (AL031032) putative protein (fragment) [Arabidopsis thaliana]
           Length = 224
           
 Score = 94.0 bits (230), Expect = 4e-18
 Identities = 57/154 (37%), Positives = 82/154 (53%), Gaps = 9/154 (5%)

Query: 7   VEDLYQRRKKILQMGGEEAIKKQHDKGKLTARERIELLLDPGS-FVEIGMFVKHRATEFG 65
           + +L    KK+L  GGEEA+K+   + KL  RERI+ LLDPGS F+E+     H   E  
Sbjct: 72  LSELRSHIKKVLAGGGEEAVKRNRSRNKLLPRERIDRLLDPGSSFLELSQLAGHELYE-- 129

Query: 66  MDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVI 125
                LP+ G+ITG G I+GR+    A D TV GG+   +   K  R  E+A     P I
Sbjct: 130 ---EPLPSGGIITGIGPIHGRICMFMANDPTVKGGTYYPITIKKHLRAQEIAARCRLPCI 186

Query: 126 GLNDSGGARIQEGVD---SLKGYGEIFKMNTILS 156
            L DSGGA + +  +     + +G +F   +++S
Sbjct: 187 YLVDSGGAYLPKQAEVFPDKENFGRVFYNESVMS 220


>pir||H81687 acetyl-coenzyme A carboxylase carboxyl transferase, beta chain
           TC0566 [imported] - Chlamydia muridarum (strain Nigg)
           >gi|7190606|gb|AAF39403.1| (AE002324) acetyl-coenzyme A
           carboxylase carboxyl transferase, beta subunit
           [Chlamydia muridarum]
           Length = 283
           
 Score = 82.7 bits (201), Expect = 9e-15
 Identities = 61/193 (31%), Positives = 101/193 (51%), Gaps = 22/193 (11%)

Query: 34  KLTARERIELLLDPGSFVEIGMFVKHRATEFGMD------------KRDLPADGVITGYG 81
           +++A ERI LL D GS+  +   +K +     +D            K +  ++GV+ G  
Sbjct: 54  RISASERIALLADEGSWNPLFSELKSQDPLHFVDTDTYSNRLEKARKNNPDSEGVLVGNC 113

Query: 82  TINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDS 141
           TI G  V +   DF+ M GS+G +   K+ R++E A+++  PVI ++ SGGAR+QE V S
Sbjct: 114 TIGGHSVALAVMDFSFMAGSMGAVVGEKLTRLIEKAIDSRWPVIIVSASGGARMQESVFS 173

Query: 142 LKGYGEIFKMNTILSGV----VPQITAIMGPCAGGAVYS-PAIGDFILMVDNPSTFMFIT 196
           L    ++ K +  L+ +    +P I+ +  P +GG   S  ++GD I  +  P   +   
Sbjct: 174 LM---QMAKTSAALAKLHEAKLPYISVLTNPTSGGVTASFASLGDVI--IAEPKALICFA 228

Query: 197 GPQVVKAVTGVDV 209
           GP+VV  V G D+
Sbjct: 229 GPRVVSQVIGEDL 241


>gb|AAB97629.1| (AF121266) malonate decarboxylase beta subunit [Acinetobacter
           calcoaceticus]
           Length = 295
           
 Score = 79.6 bits (193), Expect = 8e-14
 Identities = 60/182 (32%), Positives = 91/182 (49%), Gaps = 14/182 (7%)

Query: 36  TARERIELLLDPGSFVEIGMFVKHRATEFG--MDKRDLPA---DGVITGYGTINGRLVFV 90
           TAR RI+ ++D  SF EI   +K    E    +   D+P    DGVI G   IN   + +
Sbjct: 14  TARARIQAVVDENSFKEI---LKPTEIEVSPHLSALDIPGSFDDGVIIGTAAINQTPIHI 70

Query: 91  YAQDFTVMGGSLGEMHAMKIKRIMELAL-EAGAPVIGLNDSGGARIQEGVDSLKGYGEIF 149
            AQ+   MGG++GE+H  KI  ++  A+ +    V+   DSGG R+ E    L    EI 
Sbjct: 71  IAQEGQFMGGAVGEIHGAKIVGLLHKAIQDQSQAVVFFVDSGGVRLHEANAGLIAISEIM 130

Query: 150 K-MNTILSGVVPQITAIMGPCA--GGAVYSPAIGDFILMVDNPSTFMFITGPQVVKAVTG 206
           + M  +    +P IT I G C   GG   S  +   I+M +     + ++GP+V++ V G
Sbjct: 131 RAMLQVRHAGIPIITVIGGTCGAFGGMGISACLSSTIIMTEEGR--LALSGPEVIETVKG 188

Query: 207 VD 208
           V+
Sbjct: 189 VE 190


>pir||C72124 acetyl-coenzyme A carboxylase carboxyl transferase, beta chain
           CP0717 [imported] - Chlamydophila pneumoniae (strains
           CWL029 and AR39) >gi|4376314|gb|AAD18211.1| (AE001591)
           AcCoA Carboxylase/Transferase Beta [Chlamydophila
           pneumoniae CWL029] >gi|7189631|gb|AAF38523.1| (AE002230)
           acetyl-coenzyme A carboxylase carboxyl transferase, beta
           subunit [Chlamydophila pneumoniae AR39]
           >gi|8978432|dbj|BAA98269.1| (AP002545) AcCoA
           carboxylase/transferase beta [Chlamydophila pneumoniae
           J138]
           Length = 308
           
 Score = 79.6 bits (193), Expect = 8e-14
 Identities = 62/193 (32%), Positives = 97/193 (50%), Gaps = 22/193 (11%)

Query: 34  KLTARERIELLLDPGSFVEIGMFVKHRATEFGMD------------KRDLPADGVITGYG 81
           ++TA ER++LL D  S+  +   +K +     +D            K    ++GVI G  
Sbjct: 54  RITAIERVKLLADKDSWRPLYTDLKSQDPLEFIDTDTYANRLEKARKNTTESEGVIVGIC 113

Query: 82  TINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDS 141
           TI    V +   DF  M GS+G +   K+ R++E A+E   PVI ++ SGGAR+QE V S
Sbjct: 114 TIGLHPVALAVMDFNFMAGSMGAVVGEKLTRLIEEAIETRLPVIIVSASGGARMQESVFS 173

Query: 142 LKGYGEIFKMNTILSGV----VPQITAIMGPCAGGAVYS-PAIGDFILMVDNPSTFMFIT 196
           L    ++ K +  L+ +    +P I+ +  P +GG   S  A+GD I  +  P   +   
Sbjct: 174 LM---QMVKTSAALAKLHEAGLPYISVLTNPTSGGVTASFAALGDII--IAEPKALICFA 228

Query: 197 GPQVVKAVTGVDV 209
           GP+VV  V G D+
Sbjct: 229 GPRVVAQVIGEDL 241


>emb|CAC00894.1| (AL390935) probable propionyl-coa carboxylase beta chain homolog
           [Leishmania major]
           Length = 54
           
 Score = 79.2 bits (192), Expect = 1e-13
 Identities = 39/54 (72%), Positives = 42/54 (77%)

Query: 386 HGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADFVFAWPTAEIAVMG 439
           HGAK+LYAYAEATVP VT+I R AYGGAY  M SKHL  D  +A P AEIAVMG
Sbjct: 1   HGAKLLYAYAEATVPXVTIITRXAYGGAYDVMSSKHLRGDGXYAXPRAEIAVMG 54


>sp|P08193|ACCD_ECOLI ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA
           (ACCASE BETA CHAIN) >gi|7428518|pir||XMECBD acetyl-CoA
           carboxylase (EC 6.4.1.2), carboxyltransferase beta chain
           [validated] - Escherichia coli
           >gi|1788655|gb|AAC75376.1| (AE000320) acetylCoA
           carboxylase, carboxytransferase component, beta subunit
           [Escherichia coli K12] >gi|1799709|dbj|BAA16173.1|
           (D90863) acetyl-CoA carboxylase (EC 6.4.1.2),
           carboxyltransferase beta chain [Escherichia coli]
           Length = 304
           
 Score = 77.6 bits (188), Expect = 3e-13
 Identities = 72/243 (29%), Positives = 112/243 (45%), Gaps = 28/243 (11%)

Query: 34  KLTARERIELLLDPGSFVEIGMFV------------KHRATEFGMDKRDLPADGVITGYG 81
           ++TAR R+  LLD GS VE+G  +            K++       K     D ++   G
Sbjct: 54  RMTARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKETGEKDALVVMKG 113

Query: 82  TINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDS 141
           T+ G  V   A +F  MGGS+G +   +  R +E ALE   P+I  + SGGAR+QE + S
Sbjct: 114 TLYGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLICFSASGGARMQEALMS 173

Query: 142 LKGYGEIFKMNTILSGV----VPQITAIMGPCAGGAVYSPA-IGDFILMVDNPSTFMFIT 196
           L    ++ K +  L+ +    +P I+ +  P  GG   S A +GD  L +  P   +   
Sbjct: 174 LM---QMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGD--LNIAEPKALIGFA 228

Query: 197 GPQVVKAVTGVDVTP-VQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRL--LSYLPSNNM 253
           GP+V++      + P  Q    L+   + G   +I +  E  + L   L  L  LP+ N 
Sbjct: 229 GPRVIEQTVREKLPPGFQRSEFLI---EKGAIDMIVRRPEMRLKLASILAKLMNLPAPNP 285

Query: 254 EKP 256
           E P
Sbjct: 286 EAP 288


>pir||B71534 probable accoa carboxylase/transferase beta - Chlamydia trachomatis
           (serotype D, strain UW3/Cx) >gi|3328707|gb|AAC67886.1|
           (AE001301) AcCoA Carboxylase/Transferase Beta [Chlamydia
           trachomatis]
           Length = 308
           
 Score = 76.9 bits (186), Expect = 5e-13
 Identities = 55/169 (32%), Positives = 91/169 (53%), Gaps = 13/169 (7%)

Query: 46  DPGSFVEIGMFVKHRATEFGMDKRDLPADGVITGYGTINGRLVFVYAQDFTVMGGSLGEM 105
           DP +FV+   +  +R  +   D  D  ++GV+ G  TI    V +   DF+ M GS+G +
Sbjct: 81  DPLNFVDTDTY-PNRLEKARKDNPD--SEGVLVGVCTIGSHPVALAVMDFSFMAGSMGAV 137

Query: 106 HAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDSLKGYGEIFKMNTILSGV----VPQ 161
              K+ R++E A+++  PVI ++ SGGAR+QE V SL    ++ K +  L+ +    +P 
Sbjct: 138 VGEKLTRLIEKAIDSRLPVIIVSASGGARMQESVFSLM---QMAKTSAALAKLHEAKLPY 194

Query: 162 ITAIMGPCAGGAVYS-PAIGDFILMVDNPSTFMFITGPQVVKAVTGVDV 209
           I+ +  P +GG   S  ++GD I  +  P   +   GP+VV  V G D+
Sbjct: 195 ISVLTNPTSGGVTASFASLGDVI--IAEPKALICFAGPRVVSQVIGEDL 241


>pir||E71875 acetyl-coenzyme A carboxylase chain B - Helicobacter pylori
           (strain J99) >gi|4155465|gb|AAD06468.1| (AE001518)
           ACETYL-COENZYME A CARBOXYLASE SUBUNIT B [Helicobacter
           pylori J99]
           Length = 289
           
 Score = 76.1 bits (184), Expect = 9e-13
 Identities = 61/198 (30%), Positives = 92/198 (45%), Gaps = 20/198 (10%)

Query: 28  KQHDKGKLTARERIELLLDPGSFVEIGMFV--------------KHRATEFGMDKRDLPA 73
           K H   ++ A ERIE L D GSF E    +              K R  ++  +KR    
Sbjct: 52  KCHYHFRMNATERIEFLCDVGSFEEFDKHLRPNDPLNFVDKESYKQRIKKY--EKRTNRP 109

Query: 74  DGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGA 133
             VI+G   IN   + +   DF+ MGGSLG +   KI R +  A+     ++ ++ SGGA
Sbjct: 110 SSVISGEAKINRMPLQIVVFDFSFMGGSLGSVEGEKIVRAINRAVAKKEALLIVSASGGA 169

Query: 134 RIQEGVDSLKGYGEI-FKMNTILSGVVPQITAIMGPCAGGAVYSPA-IGDFILMVDNPST 191
           R+QE   SL    +    +N +    +P I+ +  P  GG   S A +GD  L++  P  
Sbjct: 170 RMQESTYSLMQMAKTSAALNRLSEAKLPFISLLSDPTYGGVSASFAFLGD--LIIAEPGA 227

Query: 192 FMFITGPQVVKAVTGVDV 209
            +   GP+V+K   G D+
Sbjct: 228 MIGFAGPRVIKQTIGADL 245


>pir||F64638 acetyl-CoA carboxylase beta subunit - Helicobacter pylori  (strain
           26695) >gi|2314089|gb|AAD07995.1| (AE000604) acetyl-CoA
           carboxylase beta subunit (accD) [Helicobacter pylori
           26695]
           Length = 289
           
 Score = 75.7 bits (183), Expect = 1e-12
 Identities = 61/198 (30%), Positives = 92/198 (45%), Gaps = 20/198 (10%)

Query: 28  KQHDKGKLTARERIELLLDPGSFVEIGMFV--------------KHRATEFGMDKRDLPA 73
           K H   ++ A ERIE L D GSF E    +              K R  ++  +KR    
Sbjct: 52  KCHYHFRMKAAERIEFLCDVGSFEEFDKHLRPNDPLNFVDKESYKQRIKKY--EKRTNRP 109

Query: 74  DGVITGYGTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGA 133
             VI+G   IN   + +   DF+ MGGSLG +   KI R +  A+     ++ ++ SGGA
Sbjct: 110 SSVISGEAKINRMPLQIVVFDFSFMGGSLGSVEGEKIVRAINRAVAKREALLIVSASGGA 169

Query: 134 RIQEGVDSLKGYGEI-FKMNTILSGVVPQITAIMGPCAGGAVYSPA-IGDFILMVDNPST 191
           R+QE   SL    +    +N +    +P I+ +  P  GG   S A +GD  L++  P  
Sbjct: 170 RMQESTYSLMQMAKTSAALNRLSEAKLPFISLLSDPTYGGVSASFAFLGD--LIIAEPGA 227

Query: 192 FMFITGPQVVKAVTGVDV 209
            +   GP+V+K   G D+
Sbjct: 228 MIGFAGPRVIKQTIGADL 245


>gb|AAG24832.1| (AF294436) acetyl-CoA carboxylase beta subunit [Bacillus pumilus]
           Length = 196
           
 Score = 75.7 bits (183), Expect = 1e-12
 Identities = 59/194 (30%), Positives = 92/194 (47%), Gaps = 22/194 (11%)

Query: 35  LTARERIELLLDPGSFVEIGMFV------------KHRATEFGMDKRDLPADGVITGYGT 82
           +TAR R+  LLD GS VE+G  +            K++       K     D ++   GT
Sbjct: 1   MTARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKETGEKDALVVMKGT 60

Query: 83  INGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDSL 142
           + G  V   A +F  MGGS+G +   +  R +E ALE   P+I  + SGGAR+QE + SL
Sbjct: 61  LYGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLICFSASGGARMQEALMSL 120

Query: 143 KGYGEIFKMNTILSGV----VPQITAIMGPCAGGAVYSPA-IGDFILMVDNPSTFMFITG 197
               ++ K +  L+ +    +P I+ +  P  GG   S A +GD  L +  P   +   G
Sbjct: 121 M---QMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGD--LNIAEPKALIGFAG 175

Query: 198 PQVVKAVTGVDVTP 211
           P+V++      + P
Sbjct: 176 PRVIEQTVREKLPP 189


>pir||S41121 acetyl-CoA carboxylase (EC 6.4.1.2) - human
            >gi|452316|emb|CAA48770.1| (X68968) acetyl-CoA
            carboxylase [Homo sapiens] >gi|740964|prf||2006242A
            Ac-CoA carboxylase [Homo sapiens]
            Length = 2339
            
 Score = 74.5 bits (180), Expect = 3e-12
 Identities = 89/394 (22%), Positives = 165/394 (41%), Gaps = 39/394 (9%)

Query: 86   RLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDSLKGY 145
            + +++  QD+T +  SL  +H   I+       E G     + D  G     GV++L+G 
Sbjct: 1741 KYLYLTPQDYTRIS-SLNSVHCKHIE-------EGGESRYMITDIIGKDDGLGVENLRGS 1792

Query: 146  GEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFMFITGPQVVKAVT 205
            G I   +++    +  I+ +     G   Y   +G  ++ V+N  + + +TG   +  V 
Sbjct: 1793 GMIAGESSLAYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVEN--SHIILTGASALNKVL 1850

Query: 206  GVDV--TPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSNNMEKPPRVKPKD 263
            G +V  +  QLGG  +    +G +H+    D E +  I   LSY+P +N    P + P D
Sbjct: 1851 GREVYTSNNQLGGVQI-MHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTD 1909

Query: 264  EPFRRTPELYDIVPDDPN--KAYDVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIGFGR 321
               R    L    P DP    A      +          +  F E+   +A   V G  R
Sbjct: 1910 PIDREIEFLPSRAPYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRAR 1969

Query: 322  INGQTVGIVA-----------NNPIHLAGVLDI----------DSSDKIARFVRFCDAFN 360
            + G  VG++A            +P +L     I          DS+ K A+ ++  +   
Sbjct: 1970 LGGIPVGVIAVETRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAIKDFNREK 2029

Query: 361  IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVI--LRKAYGGAYLAMG 418
            +P++ F +  G+  G+      +++ GA ++    +   P++  I  +R+  GG+++ + 
Sbjct: 2030 LPLMIFANWRGFSGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIRPMRELRGGSWVVID 2089

Query: 419  SK-HLGADFVFAWPTAEIAVMGPEGAANIIFRKE 451
            +  +     ++A   +   V+ PEG   I FRKE
Sbjct: 2090 ATINPLCIEMYADKESRGGVLEPEGTVEIKFRKE 2123


>gi|4501855 acetyl-Coenzyme A carboxylase beta [Homo sapiens]
            >gi|2493312|sp|O00763|COA2_HUMAN ACETYL-COA CARBOXYLASE 2
            (ACC-BETA) [INCLUDES: BIOTIN CARBOXYLASE ]
            >gi|2138330|gb|AAB58382.1| (U89344) acetyl-CoA
            carboxylase [Homo sapiens]
            Length = 2483
            
 Score = 74.5 bits (180), Expect = 3e-12
 Identities = 89/394 (22%), Positives = 165/394 (41%), Gaps = 39/394 (9%)

Query: 86   RLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDSLKGY 145
            + +++  QD+T +  SL  +H   I+       E G     + D  G     GV++L+G 
Sbjct: 1885 KYLYLTPQDYTRIS-SLNSVHCKHIE-------EGGESRYMITDIIGKDDGLGVENLRGS 1936

Query: 146  GEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFMFITGPQVVKAVT 205
            G I   +++    +  I+ +     G   Y   +G  ++ V+N  + + +TG   +  V 
Sbjct: 1937 GMIAGESSLAYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVEN--SHIILTGASALNKVL 1994

Query: 206  GVDV--TPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSNNMEKPPRVKPKD 263
            G +V  +  QLGG  +    +G +H+    D E +  I   LSY+P +N    P + P D
Sbjct: 1995 GREVYTSNNQLGGVQI-MHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTD 2053

Query: 264  EPFRRTPELYDIVPDDPN--KAYDVRQVIYAIVDRDENGNPDFLELQPYFAPNAVIGFGR 321
               R    L    P DP    A      +          +  F E+   +A   V G  R
Sbjct: 2054 PIDREIEFLPSRAPYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRAR 2113

Query: 322  INGQTVGIVA-----------NNPIHLAGVLDI----------DSSDKIARFVRFCDAFN 360
            + G  VG++A            +P +L     I          DS+ K A+ ++  +   
Sbjct: 2114 LGGIPVGVIAVETRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAIKDFNREK 2173

Query: 361  IPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVI--LRKAYGGAYLAMG 418
            +P++ F +  G+  G+      +++ GA ++    +   P++  I  +R+  GG+++ + 
Sbjct: 2174 LPLMIFANWRGFSGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIRPMRELRGGSWVVID 2233

Query: 419  SK-HLGADFVFAWPTAEIAVMGPEGAANIIFRKE 451
            +  +     ++A   +   V+ PEG   I FRKE
Sbjct: 2234 ATINPLCIEMYADKESRGGVLEPEGTVEIKFRKE 2267


>pir||A75422 acetyl-CoA carboxylase carboxyl transferase, beta subunit -
           Deinococcus radiodurans (strain R1)
           >gi|6458959|gb|AAF10788.1|AE001970_3 (AE001970)
           acetyl-CoA carboxylase carboxyl transferase, beta
           subunit [Deinococcus radiodurans]
           Length = 284
           
 Score = 74.1 bits (179), Expect = 3e-12
 Identities = 57/183 (31%), Positives = 85/183 (46%), Gaps = 16/183 (8%)

Query: 34  KLTARERIELLLDPGSFVEIGMFVKHRATEFGMDKRDLPA------------DGVITGYG 81
           +L+A  R+E+L DPGSF ++   V         D    P             D ++TG  
Sbjct: 54  RLSAERRVEVLADPGSFRQLSGQVHPVDPLHFTDTEPYPERLRRAQAKTGRPDAILTGTA 113

Query: 82  TINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDS 141
           T++G  V +   DF   GGS+G +   +I R  E A E+  P++ +  SGGAR+QE   S
Sbjct: 114 TLHGLPVTLAVMDFAFSGGSMGSVVGEEIARAAEYAAESRTPLLLVAASGGARMQESALS 173

Query: 142 LKGYGEIFKMNTILSG-VVPQITAIMGPCAGGAVYSPA-IGDFILMVDNPSTFMFITGPQ 199
           L    +       LSG  VP ++ +  P  GG   S A I D I  +  P   +   GP+
Sbjct: 174 LMQMAKTTVALEALSGRGVPYLSLLTDPTTGGVTASFATIADVI--IAEPGALIGFAGPR 231

Query: 200 VVK 202
           V++
Sbjct: 232 VIQ 234


>pir||C53376 hypothetical protein (iaaH 3' region) - Pseudomonas syringae pv.
           syringae >gi|472562|gb|AAA17680.1| (U04358) ORF3, which
           has sequence similarity to a number of
           carboxylase/decarboxylase subunits of CoA-requiring
           enzymes from prokaryotes and eukaryotes [Pseudomonas
           syringae]
           Length = 220
           
 Score = 73.7 bits (178), Expect = 5e-12
 Identities = 49/192 (25%), Positives = 85/192 (43%), Gaps = 15/192 (7%)

Query: 316 VIGFGRING---------QTVGIVANNPIHLAGVLDIDSSDKIARFVRFCDAFNIPIVTF 366
           + G G I+G         Q   +VANN  H  GV+   ++ K+   +      ++PI+  
Sbjct: 29  ICGAGTIHGFSRDGQPARQVFAVVANNSAHGGGVMYKRTARKMIHVIGLAGKMSLPILFI 88

Query: 367 VDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVILRKAYGGAYLAMGSKHLGADF 426
            D+PG + G + E  GI    A +  A+    V  + ++ RKAY G   AM         
Sbjct: 89  ADIPGIMIGEEAERDGIFAAVADLFRAHTRCKVKKLLLVARKAYTGGVYAMSGPGFEPVA 148

Query: 427 VFAWPTAEIAVMGPEGAANIIFRKEIAKAENPEEFRKQKIQEYREKFANPYVAASRGYID 486
           V A+P A I      G  + +  ++I K+ +  + ++  +    E+  +P +   +G I 
Sbjct: 149 VLAYPDANI------GVFSTLTMEKIIKSSSMTDAQRAVVSALDEEIRSPLLLKDKGLIT 202

Query: 487 DVIDPAETRAKI 498
           DVI   +TR  +
Sbjct: 203 DVISVRDTRQAV 214


>sp|P48937|ACCD_BRANA ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA
           (ACCASE BETA CHAIN) >gi|2144155|pir||S66564 acetyl CoA
           carboxylase type II beta-carboxyltransferase chain -
           rape chloroplast >gi|1069998|emb|CAA90747.1| (Z50868)
           acetyl CoA carboxylase carboxyltransferase (beta
           subunit) [Brassica napus] >gi|1589046|prf||2210244G
           Ac-CoA carboxylase:SUBUNIT=beta [Brassica napus]
           Length = 489
           
 Score = 73.7 bits (178), Expect = 5e-12
 Identities = 62/188 (32%), Positives = 96/188 (50%), Gaps = 24/188 (12%)

Query: 34  KLTARERIELLLDPGSF--VEIGMF----VKHRATEFGMDKRDLPA-------DGVITGY 80
           K+T+ ERIEL +DPGS+  ++  M     +K  + E    KR   A       D + TG 
Sbjct: 253 KMTSSERIELSIDPGSWNGMDEDMVSADPIKFHSREEPYKKRIASAQKKTGLTDAIQTGT 312

Query: 81  GTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVD 140
           G +NG  V +   DF  MGGS+G +   KI R++E A     P+I +  SGGAR+QEG  
Sbjct: 313 GQLNGIPVALGVMDFQFMGGSMGSVVGDKITRLIEYATNQCLPLILVCSSGGARMQEGSL 372

Query: 141 SLKGYGEIFKMNTIL-----SGVVPQITAIMGPCAGGAVYS-PAIGDFILMVDNPSTFMF 194
           SL    ++ K++++L     S  +  I+ +  P  GG   S   +GD I  +  P  ++ 
Sbjct: 373 SLM---QMAKISSVLCDYQSSKKLFYISILTSPTTGGVTASLGMLGDII--IAEPYAYIA 427

Query: 195 ITGPQVVK 202
             G +V++
Sbjct: 428 FAGKRVIE 435


>pir||G81429 acetyl-CoA carboxylase (EC 6.4.1.2) carboxyltransferase beta chain
           Cj0127c [similarity] - Campylobacter jejuni (strain NCTC
           11168) >gi|6967621|emb|CAB72611.1| (AL139074)
           acetyl-coenzyme A carboxylase carboxyl transferase
           subunit beta [Campylobacter jejuni]
           Length = 280
           
 Score = 73.4 bits (177), Expect = 6e-12
 Identities = 58/190 (30%), Positives = 94/190 (48%), Gaps = 16/190 (8%)

Query: 34  KLTARERIELLLDPGSFVEIGM---------FVKHRATEFGMDKRDLPA---DGVITGYG 81
           +++A ERI+LL D GSF+E            FV  ++ +  + + +        VI+G  
Sbjct: 54  RISADERIKLLSDEGSFIEYDANLEAIDPLKFVDSKSYKKRLSEGESKTGRKSSVISGEC 113

Query: 82  TINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDS 141
            ING    +   DF+ MGGSLG +   KI R ++ A+ +   ++ ++ SGGAR+QE   S
Sbjct: 114 EINGLKTQLVVFDFSFMGGSLGSVEGEKIVRAIQRAITSKTSLVIVSASGGARMQESTYS 173

Query: 142 LKGYGEIFKMNTILS-GVVPQITAIMGPCAGGAVYSPA-IGDFILMVDNPSTFMFITGPQ 199
           L    +      +LS   +P I+ +  P  GG   S A +GD  L++  P   +   G +
Sbjct: 174 LMQMSKTSAALKLLSKEKLPYISILTDPTMGGVSASFAWLGD--LIIAEPEALVGFAGAR 231

Query: 200 VVKAVTGVDV 209
           V+K   G D+
Sbjct: 232 VIKQTIGADL 241


>gi|11497537 acetyl-coA carboxylase beta subunit [Spinacia oleracea]
           >gi|7636118|emb|CAB88738.1| (AJ400848) acetyl-coA
           carboxylase beta subunit [Spinacia oleracea]
           Length = 522
           
 Score = 72.6 bits (175), Expect = 1e-11
 Identities = 57/188 (30%), Positives = 95/188 (50%), Gaps = 24/188 (12%)

Query: 34  KLTARERIELLLDPG----------SFVEIGMFVKHRATEFGMDKRDLPA---DGVITGY 80
           K+++ +RIELL+DPG          S   IG   +  A +  +D   +     + V TG 
Sbjct: 285 KISSSDRIELLIDPGTWNPMDDDMVSMDPIGFHSEEEAYKDRIDSYQIKTGLTEAVQTGI 344

Query: 81  GTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVD 140
           G +NG  V +   DF  MGGS+G +   KI R++E A     P+I +  SGGAR+QEG  
Sbjct: 345 GQLNGIPVAIGVMDFQFMGGSMGSVVGEKITRLIEYASNKFIPLIIVCASGGARMQEGSL 404

Query: 141 SLKGYGEIFKMNTIL-----SGVVPQITAIMGPCAGGAVYS-PAIGDFILMVDNPSTFMF 194
           SL    ++ K++++L     +  +  ++ +  P  GG   S   +GD I  +  P+ ++ 
Sbjct: 405 SLM---QMAKISSVLYDYQSNKKLFYVSILTSPTTGGVTASFGMLGDII--IAEPNAYIA 459

Query: 195 ITGPQVVK 202
             G +V++
Sbjct: 460 FAGKRVIE 467


>pir||T07012 acetyl-CoA carboxylase (EC 6.4.1.2) - potato chloroplast
           >gi|3243216|gb|AAC23997.1| (AF069288) acetyl-coenzyme A
           carboxylase carboxyl transferase [Solanum tuberosum]
           Length = 507
           
 Score = 71.8 bits (173), Expect = 2e-11
 Identities = 57/185 (30%), Positives = 91/185 (48%), Gaps = 18/185 (9%)

Query: 34  KLTARERIELLLDPGSF-------VEIGMFVKHRATEFGMDKRDLP------ADGVITGY 80
           K+++ +RIELL+DPG++       V +     H   E   D+ D         + V TG 
Sbjct: 269 KMSSSDRIELLIDPGTWDPMDEDMVSLDPIEFHSEEEPYKDRIDSYQRKTGLTEAVQTGI 328

Query: 81  GTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVD 140
           G +NG  V +   DF  MGGS+G +   KI R++E A     P+I +  SGGAR+QEG  
Sbjct: 329 GQLNGIPVAIGVMDFQFMGGSMGSVVGEKITRLIEHAANQNLPLIIVCASGGARMQEGSL 388

Query: 141 SLKGYGEIFK--MNTILSGVVPQITAIMGPCAGGAVYS-PAIGDFILMVDNPSTFMFITG 197
           SL    +I     +  L+  +  ++ +  P  GG   S   +GD I  +  P+ ++   G
Sbjct: 389 SLMQMAKISSALYDYQLNKKLFYVSILTSPTTGGVTASFGMLGDII--IAEPNAYIAFAG 446

Query: 198 PQVVK 202
            +V++
Sbjct: 447 KRVIE 451


>gi|11465966 acetyl-CoA carboxylase beta subunit [Nicotiana tabacum]
           >gi|141631|sp|P12219|ACCD_TOBAC ACETYL-COENZYME A
           CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (ACCASE
           BETA CHAIN) >gi|82218|pir||A05196 hypothetical protein
           512 - common tobacco chloroplast
           >gi|11842|emb|CAA77362.1| (Z00044) acetyl-CoA
           carboxylase beta subunit [Nicotiana tabacum]
           >gi|225210|prf||1211235AQ ORF 512 [Nicotiana tabacum]
           Length = 512
           
 Score = 71.0 bits (171), Expect = 3e-11
 Identities = 57/185 (30%), Positives = 91/185 (48%), Gaps = 18/185 (9%)

Query: 34  KLTARERIELLLDPGSF-------VEIGMFVKHRATEFGMDKRDLP------ADGVITGY 80
           K+++ +RIELL+DPG++       V +     H   E   D+ D         + V TG 
Sbjct: 274 KMSSSDRIELLIDPGTWDPMDEDMVSLDPIEFHSEEEPYKDRIDSYQRKTGLTEAVQTGI 333

Query: 81  GTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVD 140
           G +NG  V +   DF  MGGS+G +   KI R++E A     P+I +  SGGAR+QEG  
Sbjct: 334 GQLNGIPVAIGVMDFQFMGGSMGSVVGEKITRLIEYAANQILPLIIVCASGGARMQEGSL 393

Query: 141 SLKGYGEIFK--MNTILSGVVPQITAIMGPCAGGAVYS-PAIGDFILMVDNPSTFMFITG 197
           SL    +I     +  L+  +  ++ +  P  GG   S   +GD I  +  P+ ++   G
Sbjct: 394 SLMQMAKISSALYDYQLNKKLFYVSILTSPTTGGVTASFGMLGDII--IAEPNAYIAFAG 451

Query: 198 PQVVK 202
            +V++
Sbjct: 452 KRVIE 456


>gb|AAA23965.1| (M68935) acetyl-CoA carboxylase beta subunit [Escherichia coli]
           Length = 304
           
 Score = 71.0 bits (171), Expect = 3e-11
 Identities = 54/165 (32%), Positives = 81/165 (48%), Gaps = 20/165 (12%)

Query: 34  KLTARERIELLLDPGSFVEIGMFV------------KHRATEFGMDKRDLPADGVITGYG 81
           ++TAR R+  LLD GS VE+G  V            K++       K     D ++   G
Sbjct: 54  RMTARNRLHSLLDEGSLVELGSSVEPKDVLKFRDSKKYKDRLASAQKETGEKDALVVMKG 113

Query: 82  TINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDS 141
           T+ G  V   A +F  MGGS+G +   +  R +E ALE   P+I  + SGGAR+QE + S
Sbjct: 114 TLYGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLICFSASGGARMQEALMS 173

Query: 142 LKGYGEIFKMNTILSGV----VPQITAIMGPCAGGAVYSPA-IGD 181
           L    ++ K +  L+ +    +P I+ +  P  GG   S A +GD
Sbjct: 174 LM---QMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGD 215


>gi|11466711 ORF316 [Marchantia polymorpha] >gi|141629|sp|P12217|ACCD_MARPO
           ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE
           SUBUNIT BETA (ACCASE BETA CHAIN) >gi|81350|pir||A05043
           finger protein zfpA - liverwort (Marchantia polymorpha)
           chloroplast >gi|11681|emb|CAA28093.1| (X04465) ORF316
           [Marchantia polymorpha]
           Length = 316
           
 Score = 70.6 bits (170), Expect = 4e-11
 Identities = 57/187 (30%), Positives = 91/187 (48%), Gaps = 23/187 (12%)

Query: 34  KLTARERIELLLDPGSFVEIGMFVKHRATEFGMD------------KRDLPADGVITGYG 81
           ++++ ERIELL+D G++  +   +  R      D            KR    D + TG G
Sbjct: 78  QMSSTERIELLIDRGTWYPMDEDMTARDVLKFSDEDSYKNRIAFYQKRTGLTDAIQTGIG 137

Query: 82  TINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDS 141
            +NG  + +   DF  MGGS+G +   KI R++E A  A  P+I +  SGGAR+QEG  S
Sbjct: 138 QLNGIPIALGVMDFQFMGGSMGSVVGEKITRLIEYATRASMPLIIVCSSGGARMQEGTLS 197

Query: 142 LKGYGEIFKMNTILSGVVPQ-----ITAIMGPCAGGAVYS-PAIGDFILMVDNPSTFMFI 195
           L    ++ K++++L     Q     I  +  P  GG   S   +GD I  +  P  ++  
Sbjct: 198 LM---QMAKISSVLQIHQAQKRLLYIAILTYPTTGGVTASFGMLGDII--IAEPKAYIAF 252

Query: 196 TGPQVVK 202
            G +V++
Sbjct: 253 AGKRVIE 259


>pir||I41212 folC expression protein - Escherichia coli
           >gi|146008|gb|AAA23801.1| (J02808) protein required for
           folC expression [Escherichia coli]
           >gi|146019|gb|AAA23807.1| (M32445) protein of unknown
           function [Escherichia coli]
           Length = 304
           
 Score = 70.2 bits (169), Expect = 5e-11
 Identities = 56/177 (31%), Positives = 85/177 (47%), Gaps = 22/177 (12%)

Query: 34  KLTARERIELLLDPGSFVEIGMFV------------KHRATEFGMDKRDLPADGVITGYG 81
           ++TAR R+  LLD GS VE+G  +            K++       K     D ++   G
Sbjct: 54  RMTARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKETGEKDALVVMKG 113

Query: 82  TINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVDS 141
           T+ G  V   A +F  MGGS+G +   +  R +E ALE   P+I  + SGGAR+QE + S
Sbjct: 114 TLYGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLICFSASGGARMQEALMS 173

Query: 142 LKGYGEIFKMNTILSGV----VPQITAIMGPCAGGAVYSPA-IGDFILMVDNPSTFM 193
           L    ++ K +  L+ +    +P I+ +  P  GG   S A +GD  L +  P   M
Sbjct: 174 LM---QMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGD--LNIAEPKALM 225


>gi|7525042 carboxytransferase beta subunit [Arabidopsis thaliana]
           >gi|6685210|sp|P56765|ACCD_ARATH ACETYL-COENZYME A
           CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (ACCASE
           BETA CHAIN) >gi|5881703|dbj|BAA84394.1| (AP000423)
           carboxytransferase beta subunit [Arabidopsis thaliana]
           >gi|7021219|gb|AAF35256.1|AF056971_1 (AF056971)
           carboxyltransferase beta subunit [Arabidopsis thaliana]
           Length = 488
           
 Score = 69.5 bits (167), Expect = 9e-11
 Identities = 59/188 (31%), Positives = 92/188 (48%), Gaps = 24/188 (12%)

Query: 34  KLTARERIELLLDPGSF-------VEIGMFVKHRATEFGMDKRDLP------ADGVITGY 80
           K+++ ERIEL +DPG++       V       H   E   ++ D         D V TG 
Sbjct: 255 KMSSSERIELSIDPGTWNPMDEDMVSADPIKFHSKEEPYKNRIDSAQKTTGLTDAVQTGT 314

Query: 81  GTINGRLVFVYAQDFTVMGGSLGEMHAMKIKRIMELALEAGAPVIGLNDSGGARIQEGVD 140
           G +NG  V +   DF  MGGS+G +   KI R++E A     P+I +  SGGAR+QEG  
Sbjct: 315 GQLNGIPVALGVMDFRFMGGSMGSVVGEKITRLIEYATNQCLPLILVCSSGGARMQEGSL 374

Query: 141 SLKGYGEIFKMNTIL-----SGVVPQITAIMGPCAGGAVYS-PAIGDFILMVDNPSTFMF 194
           SL    ++ K++++L     S  +  I+ +  P  GG   S   +GD I  +  P  ++ 
Sbjct: 375 SLM---QMAKISSVLCDYQSSKKLFYISILTSPTTGGVTASFGMLGDII--IAEPYAYIA 429

Query: 195 ITGPQVVK 202
             G +V++
Sbjct: 430 FAGKRVIE 437


>pir||T32413 probable acetyl-CoA carboxylase (EC 6.4.1.2) W09B6.1 [similarity] -
            Caenorhabditis elegans >gi|9803022|gb|AAG00029.1|
            (AF025469) Contains similarity to Pfam domain: PF00364
            (biotin_req_enzy), Score=14.2, E-value=0.00077, N=1
            [Caenorhabditis elegans]
            Length = 2054
            
 Score = 69.5 bits (167), Expect = 9e-11
 Identities = 92/397 (23%), Positives = 166/397 (41%), Gaps = 60/397 (15%)

Query: 138  GVDSLKGYGEIFKMNTILSGVVPQITAIMGPCAGGAVYSPAIGDFILMVDNPSTFMFITG 197
            GV++L+G G I          VP    + G   G   Y+  +   I  V +  + + +TG
Sbjct: 1548 GVENLQGSGLIAGETARAYAEVPTYCYVTGRSVGIGAYTARLAHRI--VQHKQSHLILTG 1605

Query: 198  PQVVKAVTGVDV--TPVQLGGALVHAQKSGQAHLIGKSDEEVIGLIKRLLSYLPSNNMEK 255
             + +  + G  V  +  QLGG  V   ++G  H +  +D E I  + R +S+LP+   E 
Sbjct: 1606 YEALNTLLGKKVYTSNNQLGGPEVMF-RNGVTHAVVDNDLEGIAKVIRWMSFLPTPTEEF 1664

Query: 256  PPRVKPKDEPFRRTPELYDIVPDDPNK-AYDVRQVIYAIVDRDENGNPD---FLELQPYF 311
            P   K  D+   R      ++P D  +  YDVR +I +    ++ G  D   F E+   +
Sbjct: 1665 PFFSKHGDDCSARDV----VIPSDSEQNTYDVRDLIDSKNLSNQTGICDTMSFDEICGDW 1720

Query: 312  APNAVIGFGRINGQTVGIVANNPIHLAGVLDID---------------------SSDKIA 350
            A + V G  R+ G  +G+V++   + + ++  D                     S+ K A
Sbjct: 1721 AKSIVAGRARLCGIPIGVVSSEFRNFSTIVPADPAIDGSQVQNTQRAGQVWYPDSAFKTA 1780

Query: 351  RFVRFCDAFNIPIVTFVDVPGYLPGVDQESRGIIRHGAKVLYAYAEATVPMVTVI--LRK 408
              +   +  N+P++    + G+  G       +++ GA+++ A A    P++  I    +
Sbjct: 1781 EAINDLNKENLPLMIIASLRGFSGGQKDMYDMVLKFGAQIVDALAVYNRPVIVYIPEAGE 1840

Query: 409  AYGGAYLAMGSK------HLGADFVFAWPTAEIAVMGPEGAANIIFRK----EIAKAENP 458
              GGA+  + SK      HL AD       +   ++ P     I FRK    E+ K  +P
Sbjct: 1841 LRGGAWAVLDSKIRPEFIHLVAD-----EKSRGGILEPNAVVGIKFRKPMMMEMMKRSDP 1895

Query: 459  ---------EEFRKQKIQEYREKFANPYVAASRGYID 486
                     E   +++++E  E+ +  Y  AS  + D
Sbjct: 1896 TYSKLSSSTEPEAREQLEERYEELSKTYRNASVEFAD 1932


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.320    0.140    0.407 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 202250123
Number of Sequences: 2977
Number of extensions: 9157225
Number of successful extensions: 26128
Number of sequences better than 1.0e-10: 85
Number of HSP's better than  0.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 25708
Number of HSP's gapped (non-prelim): 99
length of query: 522
length of database: 189,106,746
effective HSP length: 56
effective length of query: 466
effective length of database: 155,591,474
effective search space: 72505626884
effective search space used: 72505626884
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 167 (69.5 bits)