BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1789 (cdc48-2) DE:CELL DIVISION CONTROL PROTEIN 48, AAA FAMILY (CDC48-2) (363 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||B75132 cell division control protein 48, aaa family (cdc48-... 708 0.0 pir||C71073 hypothetical protein PH1278 - Pyrococcus horikoshii ... 633 e-180 gi|11498895 cell division control protein 48, AAA family (cdc48-... 199 4e-50 gb|AAD53310.1|AF177942_1 (AF177942) katanin p60 [Xenopus laevis] 197 2e-49 gi|6754410 katanin p60 (ATPase-containing) subunit A1 [Mus muscu... 196 3e-49 gb|AAF12877.1|AF205377_1 (AF205377) p60 katanin [Chlamydomonas r... 196 3e-49 gi|5901990 katanin p60 subunit A 1 [Homo sapiens] >gi|3283072|gb... 196 3e-49 emb|CAB88114.1| (AL078581) dJ12G14.4 (katanin p60 (ATPase-contai... 196 3e-49 gi|11418569 katanin p60 (ATPase-containing) subunit A 1 [Homo sa... 196 3e-49 gb|AAF52059.1| (AE003603) katanin-60 gene product [Drosophila me... 196 4e-49 gb|AAF34687.1|AF223064_1 (AF223064) putative microtubule severin... 193 3e-48 gb|AAF21247.1|AF048706_1 (AF048706) CAD ATPase; AAA1 [Arabidopsi... 192 5e-48 gb|AAC15706.1| (AF052191) katanin p60 subunit [Strongylocentrotu... 190 1e-47 gb|AAF51955.1| (AE003601) CG1193 gene product [alt 1] [Drosophil... 187 2e-46 gb|AAF51954.1| (AE003601) CG1193 gene product [alt 2] [Drosophil... 187 2e-46 gi|6325431 AAA-type ATPase; Vps4p [Saccharomyces cerevisiae] >gi... 181 1e-44 emb|CAA63364.1| (X92680) allelic to VPS4 [Saccharomyces cerevisiae] 181 1e-44 gb|AAF21428.1|AF165422_1 (AF165422) suppressor of K+ transport g... 180 2e-44 sp|Q07590|SAV_SULAC SAV PROTEIN >gi|1076162|pir||S43859 ATPase -... 179 4e-44 pir||H72692 probable p60 katanin APE0960 - Aeropyrum pernix (str... 179 5e-44 dbj|BAB16447.1| (AP002483) putative AAA-type ATPase [Oryza sativa] 177 1e-43 gb|AAD38581.1|AF145606_1 (AF145606) BcDNA.GH02678 [Drosophila me... 177 1e-43 gb|AAF17203.1|AF112215_1 (AF112215) SKD1 protein [Homo sapiens] 177 2e-43 gi|7019569 vacuolar sorting protein 4 [Homo sapiens] >gi|5732691... 176 2e-43 gi|11430565 similar to vacuolar sorting protein 4 (H. sapiens) [... 176 2e-43 sp|Q09803|SKD1_SCHPO SUPRESSOR PROTEIN OF BEM1/BED5 DOUBLE MUTAN... 176 3e-43 gb|AAD42971.1|AF155740_1 (AF155740) vacuolar sorting protein 4 [... 175 6e-43 gb|AAC73040.1| (AC005824) putative AAA-type ATPase [Arabidopsis ... 175 7e-43 gb|AAK40746.1| AAA family ATPase [Sulfolobus solfataricus] 174 2e-42 gb|AAF76434.1|AC015445_1 (AC015445) Contains similarity to p60 k... 174 2e-42 gb|AAK40524.1| AAA family ATPase [Sulfolobus solfataricus] 173 2e-42 dbj|BAA87866.1| (AB018433) Pk-cdcA [Pyrococcus kodakaraensis] 173 2e-42 gi|6325183 Yta6p [Saccharomyces cerevisiae] >gi|2133218|pir||S61... 173 3e-42 dbj|BAB01094.1| (AB026649) gene_id:MOJ10.20~unknown protein [Ara... 173 4e-42 pir||D75046 transitional endoplasmic reticulum atpase PAB1478 - ... 172 5e-42 pir||D72613 probable transitional endoplasmic reticulum ATPase A... 172 5e-42 gi|6320887 member of the AAA ATPase family of proteins; Sap1p [S... 171 8e-42 emb|CAB60143.1| (AJ246002) spastin protein orthologue [Mus muscu... 171 1e-41 gi|7662478 spastin [Homo sapiens] >gi|5689503|dbj|BAA83035.1| (A... 170 2e-41 emb|CAB60141.1| (AJ246001) spastin protein [Homo sapiens] >gi|62... 170 2e-41 pir||F75154 cell division control protein 48, aaa family (cdc48-... 169 4e-41 gb|AAC26698.1| (AC004077) putative katanin [Arabidopsis thaliana] 169 4e-41 gb|AAD47570.1|AF134119_1 (AF134119) SKD1 [Mus musculus] 169 5e-41 gi|11425184 suppressor of K+ transport defect 1 [Homo sapiens] >... 168 9e-41 pir||B71196 probable transitional endoplasmic reticulum ATPase -... 168 9e-41 emb|CAC14616.1| (AL449144) probable AAA ATPase [Leishmania major... 168 9e-41 gb|AAF51127.1| (AE003580) CG3326 gene product [Drosophila melano... 168 1e-40 gi|4759108 suppressor of K+ transport defect 1; mouse SKD1 homol... 167 2e-40 gi|6677981 suppressor of K+ transport defect 1 [Mus musculus] >g... 167 2e-40 pir||T03922 hypothetical protein F32D1.1 - Caenorhabditis elegan... 166 5e-40 emb|CAB95999.1| (AL360054) AAA family ATPase with similarity to ... 166 5e-40 pir||H71114 probable cell division control protein (transitional... 164 1e-39 sp|Q58556|YB56_METJA CELL DIVISION CYCLE PROTEIN 48 HOMOLOG MJ11... 164 1e-39 pir||B72479 probable transitional endoplasmic reticulum ATPase A... 163 3e-39 gi|11499681 cell division control protein 48, AAA family (cdc48-... 163 3e-39 dbj|BAB02560.1| (AP000417) contains similarity to unknown protei... 162 4e-39 gb|AAK42565.1| AAA family ATPase [Sulfolobus solfataricus] 162 7e-39 gb|AAK41191.1| AAA family ATPase, p60 katanin [Sulfolobus solfat... 161 1e-38 pir||T01303 hypothetical protein T14P8.7 - Arabidopsis thaliana ... 161 1e-38 sp|P46464|CDCH_HALSA CDCH PROTEIN >gi|629399|pir||S47018 cdcH pr... 160 3e-38 gb|AAG19919.1| (AE005075) cell division cycle protein; Cdc48c [H... 160 3e-38 gb|AAF02877.1|AC009525_11 (AC009525) Unknown protein [Arabidopsi... 159 4e-38 pir||T40781 26S proteinase subunit - fission yeast (Schizosaccha... 158 1e-37 sp|P40328|TBP6_YEAST PROBABLE 26S PROTEASE SUBUNIT YTA6 (TAT-BIN... 157 2e-37 sp|Q58576|PRS1_METJA PROTEASOME-ACTIVATING NUCLEOTIDASE (PAN) (2... 157 2e-37 pir||T39584 hypothetical protein SPBC16E9.10c - fission yeast (... 156 3e-37 gi|11545833 fidgetin-like 1 [Homo sapiens] >gi|10434929|dbj|BAB1... 156 3e-37 sp|P54812|TER2_CAEEL TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE H... 156 4e-37 gi|6678559 valosin containing protein; homolog of yeast cdc48 (S... 155 5e-37 pir||VPPG transitional endoplasmic reticulum ATPase - pig >gi|22... 155 5e-37 sp|P46462|TERA_RAT TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE (TE... 155 5e-37 gi|6005942 valosin-containing protein [Homo sapiens] >gi|1142956... 155 5e-37 pir||T06669 hypothetical protein F6I7.60 - Arabidopsis thaliana ... 155 5e-37 pir||T46437 hypothetical protein DKFZp434K0126.1 - human (fragme... 155 5e-37 sp|P03974|TERA_PIG TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE (TE... 155 9e-37 dbj|BAB09730.1| (AB015476) 26S proteasome regulatory particle ch... 155 9e-37 pir||G71242 probable 26S proteinase regulatory subunit - Pyrococ... 154 1e-36 gb|AAB40928.2| (U83085) cell division cycle protein 48 [Dictyost... 154 1e-36 pir||H75207 26s proteinase regulatory chain 4 PAB2233 - Pyrococc... 153 2e-36 gi|6320077 microsomal ATPase; Cdc48p [Saccharomyces cerevisiae] ... 153 3e-36 sp|P23787|TERA_XENLA TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE (... 153 4e-36 pir||T02901 MSP1 protein homolog T13J8.110 - Arabidopsis thalian... 152 5e-36 gb|AAD20084.1| (AC006836) putative AAA-type ATPase [Arabidopsis ... 152 6e-36 sp|O05209|VAT_THEAC VCP-LIKE ATPASE >gi|7484232|pir||T37458 VCP-... 152 8e-36 gi|11230794 fidgetin-like 1 [Mus musculus] >gi|10442029|gb|AAG17... 152 8e-36 pir||T11652 probable transitional endoplasmic reticulum ATPase -... 151 1e-35 gi|10946660 spermatogenesis associated factor [Mus musculus] >gi... 150 2e-35 gb|AAK40609.1| AAA family ATPase [Sulfolobus solfataricus] 150 2e-35 sp|P34808|MEI1_CAEEL MEIOTIC SPINDLE FORMATION PROTEIN MEI-1 >gi... 150 3e-35 sp|P54609|CC48_ARATH CELL DIVISION CYCLE PROTEIN 48 HOMOLOG >gi|... 150 3e-35 pir||T48355 transitional endoplasmic reticulum ATPase - Arabidop... 150 3e-35 sp|O26824|PRS1_METTH PUTATIVE 26S PROTEASE REGULATORY SUBUNIT HO... 149 4e-35 sp|P54774|CC48_SOYBN CELL DIVISION CYCLE PROTEIN 48 HOMOLOG (VAL... 148 7e-35 sp|P54811|TER1_CAEEL TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE H... 148 7e-35 pir||A69086 cell division control protein Cdc48 - Methanobacteri... 148 7e-35 gb|AAC27447.1| (AF047037) transitional endoplasmic reticulum ATP... 148 7e-35 gi|6322994 Yll034cp [Saccharomyces cerevisiae] >gi|2492526|sp|Q0... 148 9e-35 sp|Q96372|CC48_CAPAN CELL DIVISION CYCLE PROTEIN 48 HOMOLOG >gi|... 148 9e-35 dbj|BAB14567.1| (AK023411) unnamed protein product [Homo sapiens] 148 9e-35 pir||S47861 mei-1 protein - Caenorhabditis elegans 148 1e-34 gb|AAD27852.1|AF132553_1 (AF132553) BcDNA.GM02885 [Drosophila me... 148 1e-34 pir||T46169 CDC48-like protein - Arabidopsis thaliana >gi|663074... 148 1e-34 pir||T05873 hypothetical protein T29A15.170 - Arabidopsis thalia... 147 2e-34 gb|AAC02215.1| (AF044488) valosin-containing protein homolog [Tr... 147 2e-34 gi|11499558 26S protease regulatory subunit 4 [Archaeoglobus ful... 146 3e-34 pir||F72504 probable 26S proteinase regulatory subunit APE2012 -... 146 3e-34 emb|CAC12300.1| (AL445066) VAT-2 protein [Thermoplasma acidophilum] 146 3e-34 gb|AAF17568.1|AF202034_1 (AF202034) endoplasmic reticulum membra... 146 5e-34 gb|AAF24564.1|AC007764_6 (AC007764) F22C12.12 [Arabidopsis thali... 145 6e-34 gb|AAG19767.1| (AE005062) cell division cycle protein; Cdc48a [H... 143 4e-33 gb|AAG19776.1| (AE005063) cell division cycle protein; Cdc48b [H... 143 4e-33 gb|AAF74998.1| (AF199367) cdc48-like protein [Entamoeba histolyt... 142 5e-33 gb|AAD31547.1|U53149_5 (U53149) Contains similarity to Pfam doma... 141 2e-32 dbj|BAA83371.1| (AP000391) Similar to Arabidopsis thaliana chrom... 141 2e-32 gb|AAG20864.1| (AE005154) cell division cycle protein; Cdc48d [H... 141 2e-32 sp|P71408|FTSH_HELPY CELL DIVISION PROTEIN FTSH HOMOLOG >gi|7446... 140 2e-32 sp|Q9ZM66|FTSH_HELPJ CELL DIVISION PROTEIN FTSH HOMOLOG >gi|7446... 140 3e-32 pir||T23322 hypothetical protein K04G2.3 - Caenorhabditis elegan... 139 3e-32 gb|AAF91246.1|AF227502_1 (AF227502) proteasome regulatory ATPase... 139 3e-32 emb|CAA67594.1| (X99207) smallminded [Drosophila melanogaster] 139 4e-32 gb|AAF50566.1| (AE003559) smid gene product [Drosophila melanoga... 139 4e-32 gb|AAB66377.1| (U97567) FtsH [Helicobacter pylori] 139 6e-32 gb|AAG10801.1|AC022284_6 (AC022284) L3377.6 [Leishmania major] 138 1e-31 pir||T50928 calmodulin-binding protein [imported] - Arabidopsis ... 137 2e-31 pir||T51257 calmodulin-binding protein - Arabidopsis thaliana >g... 137 2e-31 gb|AAF05624.1| (AF059715) cell survival CED-4-interacting protei... 137 2e-31 gb|AAG29874.1| (AF313486) valosin-containing protein [Homo sapiens] 136 3e-31 emb|CAB60418.1| (AL117203) contains similarity to Pfam domain: P... 136 3e-31 pir||T31590 hypothetical protein Y48C3A.h - Caenorhabditis elegans 136 3e-31 sp|O32617|FTSH_HELFE CELL DIVISION PROTEIN FTSH HOMOLOG >gi|1127... 136 4e-31 pir||T40537 AAA family ATPase - fission yeast (Schizosaccharomyc... 136 5e-31 gb|AAC44563.1| (U59452) HpFtsH [Helicobacter pylori] 135 7e-31 pir||S51042 tat-binding protein homolog - malaria parasite (Plas... 134 1e-30 gb|AAF27916.1|AF220199_1 (AF220199) 26S proteasome regulatory su... 134 1e-30 dbj|BAB17626.1| (AB033537) 26S proteasome regulatory particle tr... 134 1e-30 gb|AAB70457.1| (U68140) nuclear VCP-like protein NVLp.2 [Homo sa... 134 1e-30 gi|4505483 nuclear VCP-like; Nuclear valosin-containing protein-... 134 1e-30 gb|AAF22526.1|AF123395_1 (AF123395) 26S proteasome AAA-ATPase su... 134 1e-30 gi|6323429 homology to the CDC48 gene product; Afg2p [Saccharomy... 134 2e-30 pir||T49647 MSP1 related protein [imported] - Neurospora crassa ... 134 2e-30 gb|AAK42941.1| AAA family ATPase [Sulfolobus solfataricus] 133 3e-30 gb|AAF53216.1| (AE003637) CG5776 gene product [Drosophila melano... 133 3e-30 gb|AAF58864.1| (AE003831) TER94 gene product [alt 1] [Drosophila... 133 3e-30 sp|Q9ZEA2|FTSH_RICPR CELL DIVISION PROTEIN FTSH HOMOLOG >gi|7446... 132 4e-30 gi|8922407 fidgetin; fidgetin; hypothetical protein FLJ10405 [Ho... 132 4e-30 gb|AAF52903.1| (AE003628) CG5395 gene product [Drosophila melano... 132 4e-30 gi|11428694 fidgetin; hypothetical protein FLJ10405 [Homo sapiens] 132 4e-30 sp|O14126|PRSA_SCHPO 26S PROTEASE REGULATORY SUBUNIT 6A >gi|7435... 132 8e-30 gi|11181772 fidgetin; fidget [Mus musculus] >gi|10442027|gb|AAG1... 132 8e-30 emb|CAB62856.1| (AL035475) hypothetical protein MAL4P2.15 [Plasm... 131 1e-29 gb|AAF01545.1|AC009325_15 (AC009325) putative cell division cont... 130 2e-29 sp|P54777|PEX6_RAT PEROXISOME ASSEMBLY FACTOR-2 (PAF-2) (PEROXIS... 130 3e-29 dbj|BAA24931.1| (D89660) peroxisome assembly factor-2 [Rattus no... 130 3e-29 gb|AAG09749.1|AF233277_1 (AF233277) peroxin-6 [Penicillium chrys... 130 3e-29 gi|6324691 26S protease regulatory subunit; Rpt5p [Saccharomyces... 129 4e-29 sp|O23894|PRSA_BRACM 26S PROTEASE REGULATORY SUBUNIT 6A HOMOLOG ... 129 4e-29 sp|O67077|FTSH_AQUAE CELL DIVISION PROTEIN FTSH HOMOLOG >gi|7446... 129 4e-29 gb|AAD46145.1| (AF081573) 19S proteasome regulatory complex subu... 129 4e-29 gb|AAF22525.1|AF123394_1 (AF123394) 26S proteasome AAA-ATPase su... 129 4e-29 sp|P46465|PRSA_ORYSA 26S PROTEASE REGULATORY SUBUNIT 6A HOMOLOG ... 129 7e-29 sp|O13764|PEX6_SCHPO PROBABLE PEROXIN-6 >gi|7492793|pir||T37816 ... 129 7e-29 sp|O04019|PRSA_ARATH 26S PROTEASE REGULATORY SUBUNIT 6A HOMOLOG ... 128 9e-29 gi|6321465 40 kDa putative membrane-spanning ATPase; Msp1p [Sacc... 128 1e-28 sp|P54776|PRSA_LYCES 26S PROTEASE REGULATORY SUBUNIT 6A HOMOLOG ... 127 1e-28 dbj|BAA88165.1| (AB024399) FtsH (FtsHcp) [Cyanidioschyzon merolae] 127 2e-28 sp|P46468|CDAT_PLAFA PUTATIVE CELL DIVISION CYCLE ATPASE >gi|552... 127 3e-28 gb|AAF91248.1|AF227504_1 (AF227504) proteasome regulatory ATPase... 127 3e-28 sp|P47695|FTSH_MYCGE CELL DIVISION PROTEIN FTSH HOMOLOG >gi|1361... 126 3e-28 gb|AAB63647.1| (AC001645) cell division protein FtsH isolog [Ara... 125 7e-28 gb|AAF47769.1| (AE003478) CG12010 gene product [Drosophila melan... 125 7e-28 dbj|BAB01269.1| (AB023046) cell division protein FtsH-like [Arab... 125 7e-28 emb|CAA56963.1| (X81072) YTA7 [Saccharomyces cerevisiae] 125 1e-27 gi|6321709 26S proteasome ATPase; Yta7p [Saccharomyces cerevisia... 125 1e-27 emb|CAB58003.1| (AL121800) BACN5I9.i [Drosophila melanogaster] >... 125 1e-27 emb|CAB58013.1| (AL121800) BACN5I9.gs.8 [Drosophila melanogaster] 125 1e-27 sp|P75120|FTSH_MYCPN CELL DIVISION PROTEIN FTSH HOMOLOG >gi|2146... 124 1e-27 pir||T03904 hypothetical protein F39G3.7 - Caenorhabditis elegan... 124 1e-27 gi|11467752 hypothetical chloroplast RF25 [Guillardia theta] >gi... 124 2e-27 emb|CAA47023.1| (X66400) sug1 [Saccharomyces cerevisiae] >gi|119... 123 2e-27 gi|6321390 ATPase; Rpt6p [Saccharomyces cerevisiae] >gi|1709801|... 123 2e-27 prf||1813279A SUG1 gene [Saccharomyces cerevisiae] 123 2e-27 gb|AAB70882.1| (U77918) spermatogenic cell/sperm-associated Tat-... 123 2e-27 sp|P34124|PRS8_DICDI 26S PROTEASE REGULATORY SUBUNIT 8 (TAT-BIND... 123 3e-27 pir||A48667 peroxisomal assembly protein 5 - yeast (Pichia pasto... 123 4e-27 sp|Q25544|PRS8_NAEFO 26S PROTEASE REGULATORY SUBUNIT 8 HOMOLOG (... 123 4e-27 sp|O42586|PRSB_XENLA 26S PROTEASE REGULATORY SUBUNIT 6A (TAT-BIN... 123 4e-27 pir||D82934 ATP-dependent zinc metallopeptidase, cell division p... 123 4e-27 gi|4506211 proteasome (prosome, macropain) 26S subunit, ATPase, ... 122 5e-27 gb|AAB24840.1| Tat binding protein 1, TBP-1=transcriptional acti... 122 5e-27 sp|P33289|PEX6_PICPA PEROXISOME BIOSYNTHESIS PROTEIN PAS5 (PEROX... 122 5e-27 sp|P17980|PRSA_HUMAN 26S PROTEASE REGULATORY SUBUNIT 6A (TAT-BIN... 122 5e-27 sp|Q63569|PRSA_RAT 26S PROTEASE REGULATORY SUBUNIT 6A (TAT-BINDI... 122 5e-27 sp|P46470|PRS8_XENLA 26S PROTEASE REGULATORY SUBUNIT 8 (SUG1 HOM... 122 5e-27 sp|O42587|PRSA_XENLA 26S PROTEASE REGULATORY SUBUNIT 6A (TAT-BIN... 122 5e-27 gi|11437005 proteasome (prosome, macropain) 26S subunit, ATPase,... 122 5e-27 gi|11465515 unknown; cell division protein [Cyanidium caldarium]... 122 6e-27 gi|6679503 proteasome (prosome, macropain) 26S subunit, ATPase 3... 121 1e-26 emb|CAB51029.1| (AJ243808) metalloprotease FtsH [Bradyrhizobium ... 121 1e-26 sp|P71377|FTH1_HAEIN CELL DIVISION PROTEIN FTSH HOMOLOG 1 >gi|15... 120 2e-26 gb|AAB60775.1| (AC000375) Similar to Xenopus TER ATPase (gb|X542... 120 2e-26 pir||D75502 cell division protein FtsH - Deinococcus radiodurans... 120 2e-26 pir||T33155 hypothetical protein F56H1.4 - Caenorhabditis elegan... 120 3e-26 gb|AAD25809.1|AC006550_17 (AC006550) Belongs to PF|00004 ATPases... 119 6e-26 gb|AAD52812.1|AF129874_1 (AF129874) peroxin-6 [Pichia angusta] 118 7e-26 gi|11465793 hypothetical chloroplast ORF 25. [Porphyra purpurea]... 118 1e-25 pir||T44596 26S proteasome regulatory complex chain p50 [importe... 118 1e-25 sp|P73179|FTH2_SYNY3 CELL DIVISION PROTEIN FTSH HOMOLOG 2 >gi|74... 118 1e-25 sp|Q55700|FTH1_SYNY3 CELL DIVISION PROTEIN FTSH HOMOLOG 1 >gi|74... 116 3e-25 pir||T00863 hypothetical protein F17K2.3 - Arabidopsis thaliana ... 116 3e-25 pir||D75448 cell division protein FtsH - Deinococcus radiodurans... 116 3e-25 sp|P54816|TBP7_CAEEL TAT-BINDING HOMOLOG 7 >gi|7498868|pir||T207... 116 5e-25 gb|AAF58736.1| (AE003828) CG11919 gene product [Drosophila melan... 116 5e-25 sp|P94304|FTSH_BACFI CELL DIVISION PROTEIN FTSH HOMOLOG >gi|1813... 115 6e-25 sp|P36966|PEX6_YARLI PEROXISOME BIOSYNTHESIS PROTEIN PAY4 (PEROX... 115 1e-24 dbj|BAB00559.1| (AP001299) contains similarity to 26S proteasome... 114 1e-24 sp|P42811|PRS2_METTM PUTATIVE 26S PROTEASE REGULATORY SUBUNIT HO... 112 7e-24 pir||D70198 cell division protein (ftsH) homolog - Lyme disease ... 111 2e-23 emb|CAB51031.1| (AJ243811) l(3)70Da [Drosophila melanogaster] 111 2e-23 gb|AAF49760.1| (AE003536) l(3)70Da gene product [Drosophila mela... 111 2e-23 dbj|BAB03804.1| (AP001507) cell-division protein (ATP-dependent ... 110 3e-23 gi|11498088 AAA superfamily ATPase [Archaeoglobus fulgidus] >gi|... 105 9e-22 dbj|BAA85441.1| (AP000616) EST D15969(C1695) corresponds to a re... 104 1e-21 sp|P46509|YL15_MYCLE PUTATIVE AAA-FAMILY ATPASE MLCB2533.12/A212... 104 2e-21 gi|4507173 paraplegin [Homo sapiens] >gi|3273089|emb|CAA76314.1|... 102 8e-21 gb|AAD28099.1| (AF080525) paraplegin [Homo sapiens] 102 8e-21 pir||G01234 N-ethylmaleimide-sensitive factor - human (fragment)... 93 5e-18 gi|11079228 N-ethylmaleimide-sensitive factor [Homo sapiens] >gi... 93 5e-18 gb|AAF04745.2|AF102846_1 (AF102846) N-ethylmaleimide-sensitive f... 93 5e-18 pir||S04235 vesicular fusion protein NSF - Chinese hamster (frag... 92 7e-18 sp|P18708|NSF_CRIGR VESICULAR-FUSION PROTEIN NSF (N-ETHYLMALEIMI... 92 7e-18 gi|6679140 N-ethylmaleimide sensitive fusion protein [Mus muscul... 92 7e-18 gb|AAD39485.1|AF142097_1 (AF142097) N-ethylmaleimide sensitive f... 92 7e-18 gb|AAC46844.1| (U28836) N-ethylmaleimide sensitive fusion protei... 89 8e-17 sp|P54351|NSF2_DROME VESICULAR-FUSION PROTEIN NSF2 (N-ETHYLMALEI... 89 8e-17 gb|AAF54995.1| (AE003702) Nsf2 gene product [Drosophila melanoga... 89 8e-17 sp|P46461|NSF1_DROME VESICULAR-FUSION PROTEIN NSF1 (N-ETHYLMALEI... 88 2e-16 gb|AAF48244.1| (AE003492) comt gene product [Drosophila melanoga... 88 2e-16 gb|AAF18300.1|AF118384_1 (AF118384) N-ethylmaleimide sensitive f... 86 7e-16 pir||T18421 hypothetical protein C0140c - malaria parasite (Plas... 78 1e-13 gb|AAF26780.1|AC016829_4 (AC016829) unknown protein [Arabidopsis... 69 6e-11 pir||S74396 hypothetical protein slr0480 - Synechocystis sp. (st... 69 7e-11 >pir||B75132 cell division control protein 48, aaa family (cdc48-2) PAB1789 - Pyrococcus abyssi (strain Orsay) >gi|5458282|emb|CAB49771.1| (AJ248285) CELL DIVISION CONTROL PROTEIN 48, AAA FAMILY (CDC48-2) [Pyrococcus abyssi] Length = 363 Score = 708 bits (1807), Expect = 0.0 Identities = 363/363 (100%), Positives = 363/363 (100%) Query: 1 MYRLQLLQVQKCQEEFERALSLGHYDKARLIALRCAELLRKIASENLSLSHILLEEAKKW 60 MYRLQLLQVQKCQEEFERALSLGHYDKARLIALRCAELLRKIASENLSLSHILLEEAKKW Sbjct: 1 MYRLQLLQVQKCQEEFERALSLGHYDKARLIALRCAELLRKIASENLSLSHILLEEAKKW 60 Query: 61 EEKAKNVRKRREGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPIEP 120 EEKAKNVRKRREGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPIEP Sbjct: 61 EEKAKNVRKRREGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPIEP 120 Query: 121 PQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLS 180 PQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLS Sbjct: 121 PQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLS 180 Query: 181 PSVIFIDEVDSLTMKRVSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM 240 PSVIFIDEVDSLTMKRVSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM Sbjct: 181 PSVIFIDEVDSLTMKRVSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM 240 Query: 241 LSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLAT 300 LSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLAT Sbjct: 241 LSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLAT 300 Query: 301 MKMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKE 360 MKMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKE Sbjct: 301 MKMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKE 360 Query: 361 FAI 363 FAI Sbjct: 361 FAI 363 >pir||C71073 hypothetical protein PH1278 - Pyrococcus horikoshii >gi|3257698|dbj|BAA30381.1| (AP000005) 363aa long hypothetical protein [Pyrococcus horikoshii] Length = 363 Score = 633 bits (1614), Expect = e-180 Identities = 311/363 (85%), Positives = 348/363 (95%) Query: 1 MYRLQLLQVQKCQEEFERALSLGHYDKARLIALRCAELLRKIASENLSLSHILLEEAKKW 60 M+RLQ+LQVQKC EEFE+A++LG YDKARLIALRC+ELLR +ASENL LSHILLEEAKKW Sbjct: 1 MHRLQILQVQKCHEEFEKAMALGQYDKARLIALRCSELLRNLASENLDLSHILLEEAKKW 60 Query: 61 EEKAKNVRKRREGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPIEP 120 E+KA+N+RK++E +NEYFD+LK LIK+ST+TWNDIGGL+EAKKLIAQA+GLSIAKSPI+P Sbjct: 61 EDKARNIRKKKEARNEYFDRLKVLIKKSTVTWNDIGGLKEAKKLIAQAVGLSIAKSPIDP 120 Query: 121 PQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLS 180 PQGILLFGPPGTGKSLLASA ANSLNATFFSVKASDLLSKYFGESSKL+SALFSLARQLS Sbjct: 121 PQGILLFGPPGTGKSLLASATANSLNATFFSVKASDLLSKYFGESSKLVSALFSLARQLS 180 Query: 181 PSVIFIDEVDSLTMKRVSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM 240 PSVIFIDEVDSLTMKR SLDDAARRMIGTLLAE+DGFK+++ KVIVLTATN PWDLDEAM Sbjct: 181 PSVIFIDEVDSLTMKRSSLDDAARRMIGTLLAEIDGFKDKRRKVIVLTATNTPWDLDEAM 240 Query: 241 LSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLAT 300 LSRLPIRIYVPLPD+ SAVEIF+IHLRGI ++V L++LAKEAVK+LYSGREIANVVKLAT Sbjct: 241 LSRLPIRIYVPLPDIPSAVEIFRIHLRGIPHEVSLNKLAKEAVKKLYSGREIANVVKLAT 300 Query: 301 MKMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKE 360 MKMLEEMNPEL DPLRV+TLKG+DLTTRPLT+DDF+YAMA+IKSPITKSDVKKYE+WAKE Sbjct: 301 MKMLEEMNPELVDPLRVATLKGKDLTTRPLTMDDFRYAMAKIKSPITKSDVKKYEKWAKE 360 Query: 361 FAI 363 F I Sbjct: 361 FGI 363 >gi|11498895 cell division control protein 48, AAA family (cdc48-1) [Archaeoglobus fulgidus] >gi|7435749|pir||H69411 cell division control protein 48, AAA family (cdc48-1) homolog - Archaeoglobus fulgidus >gi|2649281|gb|AAB89948.1| (AE001014) cell division control protein 48, AAA family (cdc48-1) [Archaeoglobus fulgidus] Length = 733 Score = 199 bits (501), Expect = 4e-50 Identities = 129/332 (38%), Positives = 190/332 (56%), Gaps = 27/332 (8%) Query: 49 LSHILLEEAKKWEEKAKNVRKRREGKNEYFDKLK------ALIKRSTITWNDIGGLREAK 102 L I +E + E +N++ RE E ++ L++ + W DIGGL AK Sbjct: 405 LPEIDIEAEEIPAEVIENLKVTREDFMEALKNIEPSAMREVLVEVPNVKWEDIGGLEHAK 464 Query: 103 KLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASD 156 + + +A+ + + I+PP+GILLFGPPGTGK+LLA AVAN NA F SVK + Sbjct: 465 QELMEAVEWPLKYPEVFRAANIKPPRGILLFGPPGTGKTLLAKAVANESNANFISVKGPE 524 Query: 157 LLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDA--ARRMIGTLLAEM 214 LLSK+ GES K + +F ARQ++P VIF DE+DSL +R + D+ R++ LL E+ Sbjct: 525 LLSKWVGESEKHVREMFRKARQVAPCVIFFDEIDSLAPRRGGIGDSHVTERVVSQLLTEL 584 Query: 215 DGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRG--IH 270 DG +E KD V+V+ ATN P +D A+L RL IY+P PD + VEIFKIHLRG + Sbjct: 585 DGLEELKD-VVVIAATNRPDMIDPALLRPGRLERHIYIPPPDKKARVEIFKIHLRGKPLA 643 Query: 271 YDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEM-NPELSDPLRVSTLKGRDLTTRP 329 DV + LA++ YSG +I V + A M + E+ P ++ K +T + Sbjct: 644 DDVNIEELAEKT--EGYSGADIEAVCREAGMLAIRELIKPGMTREEAKEAAKKLKITKK- 700 Query: 330 LTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 F+ A+ +++ +TK DV+KYE+ ++F Sbjct: 701 ----HFEEALKKVRPSLTKEDVEKYEKLIEDF 728 Score = 155 bits (389), Expect = 5e-37 Identities = 99/273 (36%), Positives = 156/273 (56%), Gaps = 20/273 (7%) Query: 85 IKRST--ITWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFGPPGTGKS 135 +KR+ +T+ DIGGL+ +L+ + I L + K P IEPP+G+LL+GPPGTGK+ Sbjct: 172 VKRAVPDVTYEDIGGLKRELRLVREMIELPL-KHPELFQRLGIEPPKGVLLYGPPGTGKT 230 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 L+A AVAN ++A F + +++SKY+GES + + +F A++ +PS+IFIDE+DS+ K Sbjct: 231 LIAKAVANEVDAHFIPISGPEIMSKYYGESEQRLREIFEEAKENAPSIIFIDEIDSIAPK 290 Query: 196 RVSL-DDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPL 252 R + + RR++ LLA MDG + R D VIV+ ATN P +D A+ R I + + Sbjct: 291 REEVTGEVERRVVAQLLALMDGLEARGD-VIVIAATNRPDAIDPALRRPGRFDREIEIGV 349 Query: 253 PDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPE 310 PD EI +IH R + DV L LA+ + + G ++ + K A M L + PE Sbjct: 350 PDKEGRKEILEIHTRKMPLAEDVDLEELAE--LTNGFVGADLEALCKEAAMHALRRVLPE 407 Query: 311 LSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIK 343 + + + + +T +DF A+ I+ Sbjct: 408 ID--IEAEEIPAEVIENLKVTREDFMEALKNIE 438 >gb|AAD53310.1|AF177942_1 (AF177942) katanin p60 [Xenopus laevis] Length = 486 Score = 197 bits (495), Expect = 2e-49 Identities = 123/317 (38%), Positives = 182/317 (56%), Gaps = 32/317 (10%) Query: 69 KRREGKNEYFDKLKALIK-----RSTITWNDIGGLREAKKLIAQAIGLSI-----AKSPI 118 KR +G D ++AL + I W+DI L EAKKL+ +A+ L + K Sbjct: 177 KRFDGSGYDKDLIEALERDIISQNPNIRWDDIADLEEAKKLLKEAVVLPMWMPEFFKGIR 236 Query: 119 EPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQ 178 P +G+L+ GPPGTGK+LLA AVA TFF++ +S L SKY GES KL+ LF +AR Sbjct: 237 RPWKGVLMVGPPGTGKTLLAKAVATECKTTFFNISSSTLTSKYRGESEKLVRLLFEMARF 296 Query: 179 LSPSVIFIDEVDSLTMKRVSLD--DAARRMIGTLLAEMDGF---KERKD---KVIVLTAT 230 +P+ IFIDE+DS+ +R + + +A+RR+ LL +MDG E +D V+VL AT Sbjct: 297 YAPTTIFIDEIDSICSRRGTSEEHEASRRVKAELLVQMDGVGGASENEDPSKMVMVLAAT 356 Query: 231 NAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHY--DVPLSRLAKEAVKRLYS 288 N PWD+DEA+ RL RIY+PLP E+ +I+L+ + DV + +A+ YS Sbjct: 357 NFPWDIDEALRRRLEKRIYIPLPSAKGREELLRINLKELELADDVNIECIAENMDG--YS 414 Query: 289 GREIANVVK----LATMKMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKS 344 G +I NV + +A + +E + PE L RD P T++DF+ A+ ++ Sbjct: 415 GADITNVCRDASLMAMRRRIEGLTPEEIRNL------SRDDMHMPTTMEDFEMALKKVSK 468 Query: 345 PITKSDVKKYERWAKEF 361 ++ SD++KYE+W EF Sbjct: 469 SVSASDIEKYEKWIFEF 485 >gi|6754410 katanin p60 (ATPase-containing) subunit A1 [Mus musculus] >gi|5326894|gb|AAD42087.1|AF153197_1 (AF153197) lipotransin [Mus musculus] Length = 491 Score = 196 bits (494), Expect = 3e-49 Identities = 131/338 (38%), Positives = 187/338 (54%), Gaps = 39/338 (11%) Query: 55 EEAKKWEEKAKNVRKRREGKNEYFD------KLKALIKRSTIT------WNDIGGLREAK 102 E++K EEK K E + FD L ++R I+ W DI L EAK Sbjct: 159 EQSKGREEKNKLPAAVTEPEANKFDGTGYDKDLVEALERDIISQNPNVRWYDIADLVEAK 218 Query: 103 KLIAQAIGLSI-----AKSPIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDL 157 KL+ +A+ L + K P +G+L+ GPPGTGK+LLA AVA TFF+V +S L Sbjct: 219 KLLQEAVVLPMWMPEFFKGIRRPWKGVLMVGPPGTGKTLLAKAVATECKTTFFNVSSSTL 278 Query: 158 LSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD--DAARRMIGTLLAEMD 215 SKY GES KL+ LF +AR SP+ IFIDE+DS+ +R + + +A+RRM LL +MD Sbjct: 279 TSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRRGTSEEHEASRRMKAELLVQMD 338 Query: 216 GF---KERKD---KVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGI 269 G E D V+VL ATN PWD+DEA+ RL RIY+PLP E+ +I LR + Sbjct: 339 GVGGASENDDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPSAKGREELLRISLREL 398 Query: 270 HY--DVPLSRLAKEAVKRLYSGREIANVVK----LATMKMLEEMNPELSDPLRVSTLKGR 323 DV L+ +A+ YSG +I NV + +A + +E + PE L R Sbjct: 399 ELADDVNLASIAEN--MEGYSGADITNVCRDASLMAMRRRIEGLTPEEIRNL------SR 450 Query: 324 DLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 + P T++DF+ A+ +I ++ +D+++YE+W EF Sbjct: 451 EAMHMPTTMEDFEMALKKISKSVSAADIERYEKWIVEF 488 >gb|AAF12877.1|AF205377_1 (AF205377) p60 katanin [Chlamydomonas reinhardtii] Length = 558 Score = 196 bits (493), Expect = 3e-49 Identities = 121/329 (36%), Positives = 187/329 (56%), Gaps = 36/329 (10%) Query: 62 EKAKNVRKRREGKNEYFDKLKALIKR------STITWNDIGGLREAKKLIAQAIGLSIAK 115 EKAK K+ G ++ +L A+++R +++ W+DI GL EAK+++ +A+ L + Sbjct: 234 EKAK---KQYSGPDQ---ELAAMLERDIVDQGTSVKWDDIAGLEEAKRVLNEALVLPMIM 287 Query: 116 SPI-----EPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLIS 170 P +G+LLFGPPGTGK++LA A A + TFF+V ++ L SKY GES +++ Sbjct: 288 PDFFTGIRRPVKGVLLFGPPGTGKTMLAKAAATETSCTFFNVSSATLASKYRGESERMVR 347 Query: 171 ALFSLARQLSPSVIFIDEVDSLTMKRVSLD--DAARRMIGTLLAEMDGFK-ERKDK---- 223 LF +AR L+PS+IFIDEVDSL +R + + +A+RR+ LL ++DG KDK Sbjct: 348 ILFEMARDLAPSMIFIDEVDSLCSQRGTANEHEASRRVKTELLTQVDGVHGSEKDKEPGP 407 Query: 224 ---------VIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVP 274 V VL ATN PWD+DEA+ RL R+Y+PLP +++ KI+LR + Sbjct: 408 DGEPPAPKHVFVLAATNFPWDIDEALRRRLEKRVYIPLPGQAQRLQLLKINLRDVAVAPD 467 Query: 275 LSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVSTLKGRDLT--TRPLTL 332 ++ A YSG +I NV + A M + + P + L+ +T P+T Sbjct: 468 VNLEAVAGQMDGYSGDDITNVCRDAAMNGMRRLVAG-KTPAEIKALREAGMTGGQEPITS 526 Query: 333 DDFKYAMARIKSPITKSDVKKYERWAKEF 361 DDF+ A+ +I ++K D+K++E W F Sbjct: 527 DDFREALRKINPSVSKEDIKRHEEWLSVF 555 >gi|5901990 katanin p60 subunit A 1 [Homo sapiens] >gi|3283072|gb|AAC25114.1| (AF056022) p60 katanin [Homo sapiens] Length = 491 Score = 196 bits (493), Expect = 3e-49 Identities = 127/334 (38%), Positives = 188/334 (56%), Gaps = 31/334 (9%) Query: 55 EEAKKWEEKAKNVRKRREGKNEYFDK------LKALIKRSTIT------WNDIGGLREAK 102 E+ K EEK K+ E + FD L ++R I+ W+DI L EAK Sbjct: 159 EQNKGREEKNKSPAAVTEPETNKFDSTGYDKDLVEALERDIISQNPNVRWDDIADLVEAK 218 Query: 103 KLIAQAIGLSI-----AKSPIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDL 157 KL+ +A+ L + K P +G+L+ GPPGTGK+LLA AVA TFF+V +S L Sbjct: 219 KLLKEAVVLPMWMPEFFKGIRRPWKGVLMVGPPGTGKTLLAKAVATECKTTFFNVSSSTL 278 Query: 158 LSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD--DAARRMIGTLLAEMD 215 SKY GES KL+ LF +AR SP+ IFIDE+DS+ +R + + +A+RR+ LL +MD Sbjct: 279 TSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRRGTSEEHEASRRVKAELLVQMD 338 Query: 216 GF---KERKD---KVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGI 269 G E D V+VL ATN PWD+DEA+ RL RIY+PLP E+ +I LR + Sbjct: 339 GVGGTSENDDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPSAKGREELLRISLREL 398 Query: 270 HY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVSTLKGRDLTT 327 DV L+ +A+ YSG +I NV + A++ + L+ P + L ++ Sbjct: 399 ELADDVDLASIAEN--MEGYSGADITNVCRDASLMAMRRRIEGLT-PEEIRNLSKEEM-H 454 Query: 328 RPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 P T++DF+ A+ ++ ++ +D+++YE+W EF Sbjct: 455 MPTTMEDFEMALKKVSKSVSAADIERYEKWIFEF 488 >emb|CAB88114.1| (AL078581) dJ12G14.4 (katanin p60 (ATPase-containing) subunit A 1) [Homo sapiens] Length = 384 Score = 196 bits (493), Expect = 3e-49 Identities = 127/334 (38%), Positives = 188/334 (56%), Gaps = 31/334 (9%) Query: 55 EEAKKWEEKAKNVRKRREGKNEYFDK------LKALIKRSTIT------WNDIGGLREAK 102 E+ K EEK K+ E + FD L ++R I+ W+DI L EAK Sbjct: 52 EQNKGREEKNKSPAAVTEPETNKFDSTGYDKDLVEALERDIISQNPNVRWDDIADLVEAK 111 Query: 103 KLIAQAIGLSI-----AKSPIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDL 157 KL+ +A+ L + K P +G+L+ GPPGTGK+LLA AVA TFF+V +S L Sbjct: 112 KLLKEAVVLPMWMPEFFKGIRRPWKGVLMVGPPGTGKTLLAKAVATECKTTFFNVSSSTL 171 Query: 158 LSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD--DAARRMIGTLLAEMD 215 SKY GES KL+ LF +AR SP+ IFIDE+DS+ +R + + +A+RR+ LL +MD Sbjct: 172 TSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRRGTSEEHEASRRVKAELLVQMD 231 Query: 216 GF---KERKD---KVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGI 269 G E D V+VL ATN PWD+DEA+ RL RIY+PLP E+ +I LR + Sbjct: 232 GVGGTSENDDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPSAKGREELLRISLREL 291 Query: 270 HY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVSTLKGRDLTT 327 DV L+ +A+ YSG +I NV + A++ + L+ P + L ++ Sbjct: 292 ELADDVDLASIAEN--MEGYSGADITNVCRDASLMAMRRRIEGLT-PEEIRNLSKEEM-H 347 Query: 328 RPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 P T++DF+ A+ ++ ++ +D+++YE+W EF Sbjct: 348 MPTTMEDFEMALKKVSKSVSAADIERYEKWIFEF 381 >gi|11418569 katanin p60 (ATPase-containing) subunit A 1 [Homo sapiens] Length = 385 Score = 196 bits (493), Expect = 3e-49 Identities = 127/334 (38%), Positives = 188/334 (56%), Gaps = 31/334 (9%) Query: 55 EEAKKWEEKAKNVRKRREGKNEYFDK------LKALIKRSTIT------WNDIGGLREAK 102 E+ K EEK K+ E + FD L ++R I+ W+DI L EAK Sbjct: 54 EQNKGREEKNKSPAAVTEPETNKFDSTGYDKDLVEALERDIISQNPNVRWDDIADLVEAK 113 Query: 103 KLIAQAIGLSI-----AKSPIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDL 157 KL+ +A+ L + K P +G+L+ GPPGTGK+LLA AVA TFF+V +S L Sbjct: 114 KLLKEAVVLPMWMPEFFKGIRRPWKGVLMVGPPGTGKTLLAKAVATECKTTFFNVSSSTL 173 Query: 158 LSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD--DAARRMIGTLLAEMD 215 SKY GES KL+ LF +AR SP+ IFIDE+DS+ +R + + +A+RR+ LL +MD Sbjct: 174 TSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRRGTSEEHEASRRVKAELLVQMD 233 Query: 216 GF---KERKD---KVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGI 269 G E D V+VL ATN PWD+DEA+ RL RIY+PLP E+ +I LR + Sbjct: 234 GVGGTSENDDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPSAKGREELLRISLREL 293 Query: 270 HY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVSTLKGRDLTT 327 DV L+ +A+ YSG +I NV + A++ + L+ P + L ++ Sbjct: 294 ELADDVDLASIAEN--MEGYSGADITNVCRDASLMAMRRRIEGLT-PEEIRNLSKEEM-H 349 Query: 328 RPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 P T++DF+ A+ ++ ++ +D+++YE+W EF Sbjct: 350 MPTTMEDFEMALKKVSKSVSAADIERYEKWIFEF 383 >gb|AAF52059.1| (AE003603) katanin-60 gene product [Drosophila melanogaster] Length = 554 Score = 196 bits (492), Expect = 4e-49 Identities = 117/290 (40%), Positives = 174/290 (59%), Gaps = 16/290 (5%) Query: 84 LIKRSTITWNDIGGLREAKKLIAQAIGLSIA-----KSPIEPPQGILLFGPPGTGKSLLA 138 L K + W+DI L +AK+L+ +A+ L + K P +G+L+ GPPGTGK++LA Sbjct: 266 LQKDPKVRWSDIADLHDAKRLLEEAVVLPMLMPDYFKGIRRPWKGVLMVGPPGTGKTMLA 325 Query: 139 SAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR-- 196 AVA TFF+V ++ L SKY GES K++ LF +AR +PS IFIDE+DSL +R Sbjct: 326 KAVATECGTTFFNVSSATLTSKYRGESEKMVRLLFEMARFYAPSTIFIDEIDSLCSRRGS 385 Query: 197 VSLDDAARRMIGTLLAEMDGF---KERKDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLP 253 S +A+RR+ LL +MDG +E+ V+VL ATN PWD+DEA+ RL RIY+PLP Sbjct: 386 ESEHEASRRVKSELLVQMDGVGGGEEQAKVVMVLAATNFPWDIDEALRRRLEKRIYIPLP 445 Query: 254 DVNSAVEIFKIHLRGIHYD--VPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPEL 311 + KI+LR + D V L+ +A E + YSG +I NV + A+M + L Sbjct: 446 SDEGREALLKINLREVKVDDSVDLTYVANEL--KGYSGADITNVCREASMMSMRRKIAGL 503 Query: 312 SDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 + P ++ L ++ P++ DF AM+R ++++D+ KYE+W +EF Sbjct: 504 T-PEQIRQLATEEVDL-PVSNKDFNEAMSRCNKSVSRADLDKYEKWMREF 551 >gb|AAF34687.1|AF223064_1 (AF223064) putative microtubule severing protein katanin p60 subunit [Drosophila melanogaster] Length = 571 Score = 193 bits (485), Expect = 3e-48 Identities = 116/289 (40%), Positives = 173/289 (59%), Gaps = 15/289 (5%) Query: 84 LIKRSTITWNDIGGLREAKKLIAQAIGLSIA-----KSPIEPPQGILLFGPPGTGKSLLA 138 L K + W+DI L +AK+L+ +A+ L + K P +G+L+ GP GTGK++LA Sbjct: 284 LQKDPKVRWSDIADLHDAKRLLEEAVVLPMLMPDYFKGIRRPWKGVLMVGPSGTGKTMLA 343 Query: 139 SAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR-- 196 AVA TFF+V ++ L SKY GES K++ LF +AR +PS IFIDE+DSL +R Sbjct: 344 KAVATECGTTFFNVSSATLTSKYRGESEKMVRLLFEMARFYAPSTIFIDEIDSLCSRRGS 403 Query: 197 VSLDDAARRMIGTLLAEMDGF--KERKDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPD 254 S +A+RR+ LL +MDG +E+ V+VL ATN PWD+DEA+ RL RIY+PLP Sbjct: 404 ESEHEASRRVKSELLVQMDGVAREEQAKVVMVLAATNFPWDIDEALRRRLEKRIYIPLPS 463 Query: 255 VNSAVEIFKIHLRGIHYD--VPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELS 312 + KI+LR + D V L+ +A E + YSG +I NV + A+M + L+ Sbjct: 464 DEGREALLKINLREVKVDDSVDLTYVANEL--KGYSGADITNVCREASMMSMRRKIAGLT 521 Query: 313 DPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 P ++ L ++ P++ DF AM+R ++++D+ KYE+W +EF Sbjct: 522 -PEQIRQLATEEVDL-PVSNKDFNEAMSRCNKSVSRADLDKYEKWMREF 568 >gb|AAF21247.1|AF048706_1 (AF048706) CAD ATPase; AAA1 [Arabidopsis thaliana] >gi|6751710|gb|AAF27692.1|AC018848_9 (AC018848) CAD ATPase (AAA1); 35570-33019 [Arabidopsis thaliana] Length = 523 Score = 192 bits (483), Expect = 5e-48 Identities = 117/323 (36%), Positives = 184/323 (56%), Gaps = 30/323 (9%) Query: 62 EKAKNVRKRREGKNEYFDKLKALIKRST------ITWNDIGGLREAKKLIAQAIGLSIAK 115 E K+ R EG +E L A+++R + W+D+ GL EAK+L+ +A+ L + Sbjct: 205 EDGKSKRGLYEGPDE---DLAAMLERDVLDSTPGVRWDDVAGLSEAKRLLEEAVVLPLWM 261 Query: 116 SPI-----EPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLIS 170 P +G+L+FGPPGTGK+LLA AVA TFF+V ++ L SK+ GES +++ Sbjct: 262 PEYFQGIRRPWKGVLMFGPPGTGKTLLAKAVATECGTTFFNVSSATLASKWRGESERMVR 321 Query: 171 ALFSLARQLSPSVIFIDEVDSLTMKR--VSLDDAARRMIGTLLAEMDGFKE-------RK 221 LF LAR +PS IFIDE+DSL R +++RR+ LL ++DG + Sbjct: 322 CLFDLARAYAPSTIFIDEIDSLCNSRGGSGEHESSRRVKSELLVQVDGVSNTATNEDGSR 381 Query: 222 DKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHY--DVPLSRLA 279 V+VL ATN PWD+DEA+ RL RIY+PLPD S + I+LR + DV + +A Sbjct: 382 KIVMVLAATNFPWDIDEALRRRLEKRIYIPLPDFESRKALININLRTVEVASDVNIEDVA 441 Query: 280 KEAVKRLYSGREIANVVKLATMK-MLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYA 338 + YSG ++ NV + A+M M ++ + D + + D++ P+ + DF+ A Sbjct: 442 RRT--EGYSGDDLTNVCRDASMNGMRRKIAGKTRD--EIKNMSKDDISNDPVAMCDFEEA 497 Query: 339 MARIKSPITKSDVKKYERWAKEF 361 + +++ ++ SD++K+E+W EF Sbjct: 498 IRKVQPSVSSSDIEKHEKWLSEF 520 >gb|AAC15706.1| (AF052191) katanin p60 subunit [Strongylocentrotus purpuratus] Length = 516 Score = 190 bits (479), Expect = 1e-47 Identities = 120/327 (36%), Positives = 182/327 (54%), Gaps = 31/327 (9%) Query: 62 EKAKNVRKRREGKNEYFDKL-----------KALIKRS-TITWNDIGGLREAKKLIAQAI 109 +K K EG + FD + +++R+ + W DI GL EAK+L+ +A+ Sbjct: 191 DKDKKAPSGEEGDEKKFDPAGYDKDLVENLERDIVQRNPNVHWADIAGLTEAKRLLEEAV 250 Query: 110 GLSI-----AKSPIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGE 164 L + K P +G+L+ GPPGTGK++LA AVA TFF+V ++ L SKY GE Sbjct: 251 VLPLWMPDYFKGIRRPWKGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSASLTSKYHGE 310 Query: 165 SSKLISALFSLARQLSPSVIFIDEVDSLTMKR--VSLDDAARRMIGTLLAEMDGF----- 217 S KL+ LF +AR +PS IFIDE+DS+ KR S +A+RR+ LL +MDG Sbjct: 311 SEKLVRLLFEMARFYAPSTIFIDEIDSICSKRGTGSEHEASRRVKSELLIQMDGVSGPSA 370 Query: 218 -KERKDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHY--DVP 274 +E V+VL ATN PWD+DEA+ RL RIY+PLP+++ ++ +I+L+ + D+ Sbjct: 371 GEESSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPEIDGREQLLRINLKEVPLADDID 430 Query: 275 LSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDD 334 L +A++ YSG +I NV + A+M + L P + + +L +P T D Sbjct: 431 LKSIAEKMDG--YSGADITNVCRDASMMAMRRRIQGLR-PEEIRHIPKEEL-NQPSTPAD 486 Query: 335 FKYAMARIKSPITKSDVKKYERWAKEF 361 F A+ ++ + K D+ KY W +EF Sbjct: 487 FLLALQKVSKSVGKEDLVKYMAWMEEF 513 >gb|AAF51955.1| (AE003601) CG1193 gene product [alt 1] [Drosophila melanogaster] Length = 554 Score = 187 bits (469), Expect = 2e-46 Identities = 112/292 (38%), Positives = 167/292 (56%), Gaps = 20/292 (6%) Query: 84 LIKRSTITWNDIGGLREAKKLIAQAIGLSIA-----KSPIEPPQGILLFGPPGTGKSLLA 138 L + I W D+ GL EAK ++ +A+ L + K P +G+L+ GPPGTGK++LA Sbjct: 266 LQRHPCIKWTDVAGLNEAKTILQEAVVLPVIMPEFFKGIRRPWRGVLMVGPPGTGKTMLA 325 Query: 139 SAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR-- 196 AVA TFF+V +S L SKY GES KL+ LF +AR +PS IFIDE+D+L R Sbjct: 326 KAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPSTIFIDEIDALCASRGS 385 Query: 197 VSLDDAARRMIGTLLAEMDGFKE--RKDKVI-VLTATNAPWDLDEAMLSRLPIRIYVPLP 253 S +A+RR LL +MDG +++KVI VL ATN PWD+DEA R RIY+PLP Sbjct: 386 DSEHEASRRFKAELLIQMDGLNASMQEEKVIMVLAATNHPWDIDEAFRRRFEKRIYIPLP 445 Query: 254 DVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATM----KMLEEMNP 309 + + + K+ L+ + L+ + YSG +I+NV + A+M +++ P Sbjct: 446 NEGTRSALLKLCLKDVCLSPSLNTGIIGDELQGYSGSDISNVCRDASMMAMRRLISGRTP 505 Query: 310 ELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 + +R R+ +P+TL DF+ A R K ++ DV ++E+W +E+ Sbjct: 506 DQIKQIR------REEVDQPITLQDFQDARLRTKKSVSADDVARFEKWMEEY 551 >gb|AAF51954.1| (AE003601) CG1193 gene product [alt 2] [Drosophila melanogaster] Length = 669 Score = 187 bits (469), Expect = 2e-46 Identities = 112/292 (38%), Positives = 167/292 (56%), Gaps = 20/292 (6%) Query: 84 LIKRSTITWNDIGGLREAKKLIAQAIGLSIA-----KSPIEPPQGILLFGPPGTGKSLLA 138 L + I W D+ GL EAK ++ +A+ L + K P +G+L+ GPPGTGK++LA Sbjct: 381 LQRHPCIKWTDVAGLNEAKTILQEAVVLPVIMPEFFKGIRRPWRGVLMVGPPGTGKTMLA 440 Query: 139 SAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR-- 196 AVA TFF+V +S L SKY GES KL+ LF +AR +PS IFIDE+D+L R Sbjct: 441 KAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPSTIFIDEIDALCASRGS 500 Query: 197 VSLDDAARRMIGTLLAEMDGFKE--RKDKVI-VLTATNAPWDLDEAMLSRLPIRIYVPLP 253 S +A+RR LL +MDG +++KVI VL ATN PWD+DEA R RIY+PLP Sbjct: 501 DSEHEASRRFKAELLIQMDGLNASMQEEKVIMVLAATNHPWDIDEAFRRRFEKRIYIPLP 560 Query: 254 DVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATM----KMLEEMNP 309 + + + K+ L+ + L+ + YSG +I+NV + A+M +++ P Sbjct: 561 NEGTRSALLKLCLKDVCLSPSLNTGIIGDELQGYSGSDISNVCRDASMMAMRRLISGRTP 620 Query: 310 ELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 + +R R+ +P+TL DF+ A R K ++ DV ++E+W +E+ Sbjct: 621 DQIKQIR------REEVDQPITLQDFQDARLRTKKSVSADDVARFEKWMEEY 666 >gi|6325431 AAA-type ATPase; Vps4p [Saccharomyces cerevisiae] >gi|1706647|sp|P52917|VPS4_YEAST VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS4 (END13 PROTEIN) >gi|2131247|pir||S59831 END13 protein - yeast (Saccharomyces cerevisiae) >gi|786322|gb|AAB68107.1| (U25842) Similar to several members of the Cdc48/Pas1/Sec18 family of proteins (Swiss Prot. accession numbers P25694, P24004, P18759) [Saccharomyces cerevisiae] Length = 437 Score = 181 bits (455), Expect = 1e-44 Identities = 118/314 (37%), Positives = 170/314 (53%), Gaps = 41/314 (13%) Query: 84 LIKRSTITWNDIGGLREAKKLIAQAIGLSIA-----KSPIEPPQGILLFGPPGTGKSLLA 138 L ++ + W D+ GL AK+ + +A+ L + K +P GILL+GPPGTGKS LA Sbjct: 124 LSEKPNVKWEDVAGLEGAKEALKEAVILPVKFPHLFKGNRKPTSGILLYGPPGTGKSYLA 183 Query: 139 SAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVS 198 AVA N+TFFSV +SDL+SK+ GES KL+ LF++AR+ PS+IFIDEVD+LT R Sbjct: 184 KAVATEANSTFFSVSSSDLVSKWMGESEKLVKQLFAMARENKPSIIFIDEVDALTGTRGE 243 Query: 199 LDDAARRMIGT-LLAEMDGFKERKDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNS 257 + A R I T LL +M+G V+VL ATN PW LD A+ R RIY+PLPD+ + Sbjct: 244 GESEASRRIKTELLVQMNGVGNDSQGVLVLGATNIPWQLDSAIRRRFERRIYIPLPDLAA 303 Query: 258 AVEIFKIHLRGIHYDVPLSRLAKEAVKRL------YSGREIANVVKLATMKMLEEMNPEL 311 +F+I++ D P L KE + L YSG +IA VVK A M+ + ++ Sbjct: 304 RTTMFEINVG----DTPCV-LTKEDYRTLGAMTEGYSGSDIAVVVKDALMQPIRKIQSAT 358 Query: 312 --------SDPLRVST----------------LKGRDLTTRPLTLDDFKYAMARIKSPIT 347 D R T ++ +L LT+ DF A+ + + Sbjct: 359 HFKDVSTEDDETRKLTPCSPGDDGAIEMSWTDIEADELKEPDLTIKDFLKAIKSTRPTVN 418 Query: 348 KSDVKKYERWAKEF 361 + D+ K E++ ++F Sbjct: 419 EDDLLKQEQFTRDF 432 >emb|CAA63364.1| (X92680) allelic to VPS4 [Saccharomyces cerevisiae] Length = 437 Score = 181 bits (455), Expect = 1e-44 Identities = 118/314 (37%), Positives = 170/314 (53%), Gaps = 41/314 (13%) Query: 84 LIKRSTITWNDIGGLREAKKLIAQAIGLSIA-----KSPIEPPQGILLFGPPGTGKSLLA 138 L ++ + W D+ GL AK+ + +A+ L + K +P GILL+GPPGTGKS LA Sbjct: 124 LSEKPNVKWEDVAGLEGAKEALKEAVILPVKFPHLFKGNRKPTSGILLYGPPGTGKSYLA 183 Query: 139 SAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVS 198 AVA N+TFFSV +SDL+SK+ GES KL+ LF++AR+ PS+IFIDEVD+LT R Sbjct: 184 KAVATEANSTFFSVSSSDLVSKWMGESEKLVKQLFAMARENKPSIIFIDEVDALTGTRGE 243 Query: 199 LDDAARRMIGT-LLAEMDGFKERKDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNS 257 + A R I T LL +M+G V+VL ATN PW LD A+ R RIY+PLPD+ + Sbjct: 244 GESEASRRIKTELLVQMNGVGNDSQGVLVLGATNIPWQLDSAIRRRFERRIYIPLPDLAA 303 Query: 258 AVEIFKIHLRGIHYDVPLSRLAKEAVKRL------YSGREIANVVKLATMKMLEEMNPEL 311 +F+I++ D P L KE + L YSG +IA VVK A M+ + ++ Sbjct: 304 RTTMFEINVG----DTPCV-LTKEDYRTLGAMTEGYSGSDIAVVVKDALMQPIRKIQSAT 358 Query: 312 --------SDPLRVST----------------LKGRDLTTRPLTLDDFKYAMARIKSPIT 347 D R T ++ +L LT+ DF A+ + + Sbjct: 359 HFKDVSTEDDETRKLTPCSPGDDGAIEMSWTDIEADELKEPDLTIKDFLKAIKSTRPTVN 418 Query: 348 KSDVKKYERWAKEF 361 + D+ K E++ ++F Sbjct: 419 EDDLLKQEQFTRDF 432 >gb|AAF21428.1|AF165422_1 (AF165422) suppressor of K+ transport growth defect-like protein [Mesembryanthemum crystallinum] Length = 317 Score = 180 bits (453), Expect = 2e-44 Identities = 112/309 (36%), Positives = 177/309 (57%), Gaps = 35/309 (11%) Query: 86 KRSTITWNDIGGLREAKKLIAQAIGLSIAKSPI-----EPPQGILLFGPPGTGKSLLASA 140 ++ + WND+ GL AK+ + +A+ L + P + LL+GPPGTGKS LA A Sbjct: 7 EKPNVKWNDVAGLESAKQALQEAVILPVKFPQFFTGKRRPWRAFLLYGPPGTGKSYLAKA 66 Query: 141 VANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR--VS 198 VA ++TFFSV +SDL+SK+ GES KL+S LF +AR+ +PS+IF+DE+DSL +R + Sbjct: 67 VATEADSTFFSVSSSDLVSKWMGESEKLVSNLFQMARESAPSIIFVDEIDSLCGQRGEGN 126 Query: 199 LDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSA 258 +A+RR+ LL +M G +KV+VL ATN P+ LD+A+ R RIY+PLPD+ + Sbjct: 127 ESEASRRIKTELLVQMQGVGHNDEKVLVLAATNTPYALDQAIRRRFDKRIYIPLPDLKAR 186 Query: 259 VEIFKIHLRGIHYDVPLSR---LAKEAVKRLYSGREIANVVKLATMKMLEEMNPEL---- 311 +FK+HL +++ S LA++A +SG +IA VK + + + + Sbjct: 187 QHMFKVHLGDTPHNLTESDFEFLARKA--EGFSGSDIAVCVKDVLFEPVRKTQDAMFFYK 244 Query: 312 -SDPLRVS---------TLKGRDLTTR---------PLTLDDFKYAMARIKSPITKSDVK 352 SD + V + +DL + P+ DF+ +AR + ++KSD++ Sbjct: 245 TSDDVWVPCGPRQPGAVQITMQDLAAKGLAAKIVPPPIARTDFEKVLARQRPTVSKSDLE 304 Query: 353 KYERWAKEF 361 +ER+ +EF Sbjct: 305 VHERFTQEF 313 >sp|Q07590|SAV_SULAC SAV PROTEIN >gi|1076162|pir||S43859 ATPase - Sulfolobus acidocaldarius >gi|310600|gb|AAA72002.1| (L17042) ATPase [Sulfolobus acidocaldarius] Length = 780 Score = 179 bits (450), Expect = 4e-44 Identities = 113/330 (34%), Positives = 188/330 (56%), Gaps = 37/330 (11%) Query: 64 AKNVRKRREGKNEYFDKLKAL---------IKRSTITWNDIGGLREAKKLIAQAIGLSI- 113 A+ +++ + N++ + LK++ ++ + WNDIGGL K+ + +A+ + Sbjct: 449 AEIIKELKVSMNDFLNALKSIQPSLLREVYVEVPKVNWNDIGGLDNVKQQLREAVEWPLR 508 Query: 114 -----AKSPIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKL 168 KS + PP+GILLFGPPGTGK++LA AVA A F +V+ ++LSK+ GES K Sbjct: 509 FPELFTKSGVTPPKGILLFGPPGTGKTMLAKAVATESGANFIAVRGPEILSKWVGESEKA 568 Query: 169 ISALFSLARQLSPSVIFIDEVDSLT-MKRVSLDD-AARRMIGTLLAEMDGFKERKDKVIV 226 I +F ARQ +P+VIF DE+DS+ ++ +S D R++ LLAEMDG +KV++ Sbjct: 569 IREIFRKARQAAPTVIFFDEIDSIAPIRGLSTDSGVTERIVNQLLAEMDGIVP-LNKVVI 627 Query: 227 LTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHY--DVPLSRLAKEA 282 + ATN P LD A+L R IYVP PD + EI K+H + + DV L +A++A Sbjct: 628 IAATNRPDILDPALLRPGRFDRLIYVPPPDKTARFEILKVHTKNVPLAEDVSLEDIAEKA 687 Query: 283 VKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVSTLKGR------------DLTTRPL 330 Y+G ++ +V+ AT+ + + + D KG + T+ + Sbjct: 688 --EGYTGADLEALVREATINAMRSIY-SMCDKQSRDECKGNMECYQKHIKECMNKTSFKV 744 Query: 331 TLDDFKYAMARIKSPITKSDVKKYERWAKE 360 + +DF+ A+ +K+ +T++D+++YER++KE Sbjct: 745 SKEDFEKALNVVKASLTQADIQRYERFSKE 774 Score = 146 bits (364), Expect = 5e-34 Identities = 92/270 (34%), Positives = 149/270 (55%), Gaps = 14/270 (5%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKSLLASAVAN 143 ++W DIG L EAK+ I + + + + I+PP+GILL+GPPGTGK+LLA A+ N Sbjct: 209 VSWEDIGDLEEAKQKIREIVEWPMRHPELFQRLGIDPPKGILLYGPPGTGKTLLARALRN 268 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL-DDA 202 + A F +V +++SK++GES + I +F A + +PS+IFIDE+D++ KR + + Sbjct: 269 EIGAYFITVNGPEIMSKFYGESEQRIREIFKEAEENAPSIIFIDEIDAIAPKREDVTGEV 328 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVE 260 +R++ LL MDG K R +VIV+ ATN P +D A+ R I + PD + Sbjct: 329 EKRVVAQLLTLMDGIKGR-GRVIVIGATNRPDAIDPALRRPGRFDREIEIRPPDTKGRKD 387 Query: 261 IFKIHLRG--IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 I ++H R I DV L +LA+ Y+G ++A + K A + L E L Sbjct: 388 ILQVHTRNMPITDDVDLDKLAEMTYG--YTGADLAALAKEAAIYALRRFVDEKKLNLDQP 445 Query: 319 TLKGRDLTTRPLTLDDFKYAMARIKSPITK 348 T+ + ++++DF A+ I+ + + Sbjct: 446 TIPAEIIKELKVSMNDFLNALKSIQPSLLR 475 >pir||H72692 probable p60 katanin APE0960 - Aeropyrum pernix (strain K1) >gi|5104629|dbj|BAA79944.1| (AP000060) 384aa long hypothetical p60 katanin [Aeropyrum pernix] Length = 384 Score = 179 bits (449), Expect = 5e-44 Identities = 125/371 (33%), Positives = 193/371 (51%), Gaps = 44/371 (11%) Query: 23 GHYDKARLIALRCAELLRKIASE--NLSLSHILLEEAKKWEEKAKNVRKRRE-----GKN 75 G Y+ A + + E L +I + L+HI ++ K K++ K+ G Sbjct: 25 GDYEAAIVNLNKAIEYLTEIVRNYPDYPLAHIYRRLIAQYRRKVKDLEKKARMIPASGDE 84 Query: 76 EYFDKLK------------ALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPIEP--- 120 Y D + L ++ ++T++DI GL EAKK I +AI + + + P Sbjct: 85 VYVDTQEKDGGGEDEAPEFVLKEKPSVTFDDIAGLEEAKKAIREAIVFPVKRPDLFPLGW 144 Query: 121 PQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLS 180 P+GILL+GPPGTGK++LASAVAN ++ F V A++++SK+ GE K + LF+ AR + Sbjct: 145 PRGILLYGPPGTGKTMLASAVANEIDGEFLYVDAANIMSKWLGEGEKNVKKLFNYARNKA 204 Query: 181 ----PSVIFIDEVDSLTMKRVSLDDAARRMIGTLLAEMDGFKERKDK--VIVLTATNAPW 234 P VIFIDEVD+L S R+ L EMDG +++ + V V+ ATN PW Sbjct: 205 KEGKPVVIFIDEVDALLGVHGSEVGGEVRVRNQFLKEMDGIQDKGSRLHVYVIAATNKPW 264 Query: 235 DLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREI 292 LDE + R RIYVPLP + + +++ R + DV L RLA+ + Y+G +I Sbjct: 265 KLDEPFIRRFQKRIYVPLPSRETRKRMLEMYTRKLRLAGDVDLDRLAE--MLEGYTGSDI 322 Query: 293 ANVVKLATMKMLEEMNPELSDPLRVSTLKGR-DLTTRPLTLDDFKYAMARIKSPITKSDV 351 A++V+ A M + E+ KG+ D RP+T+ DF+ + R + + + Sbjct: 323 ADIVREAYMATVRELFE-----------KGKVDGEPRPITMSDFQEILRRRRPSVDHRLL 371 Query: 352 KKYERWAKEFA 362 K YE W + FA Sbjct: 372 KTYEEWTERFA 382 >dbj|BAB16447.1| (AP002483) putative AAA-type ATPase [Oryza sativa] Length = 411 Score = 177 bits (445), Expect = 1e-43 Identities = 114/310 (36%), Positives = 170/310 (54%), Gaps = 39/310 (12%) Query: 87 RSTITWNDIGGLREAKKLIAQAIGLSIA-----KSPIEPPQGILLFGPPGTGKSLLASAV 141 + ++ W+D+ GL AK+ + +A L I P + LL+GPPGTGKS LA AV Sbjct: 103 KPSVKWSDVAGLESAKEALQEAAILPIKFPHFFTGKRSPWKAFLLYGPPGTGKSYLAEAV 162 Query: 142 ANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR--VSL 199 A +++TFFS+ +SDL+SK+ GES KL++ LF +AR+ +PS+IFIDE+DSL +R + Sbjct: 163 ATEVDSTFFSISSSDLVSKWMGESEKLVANLFQMARENAPSIIFIDEIDSLCGQRGECNE 222 Query: 200 DDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAV 259 ++A+RR+ LL +M GF DKV+VL ATN P LD+AM R IY+PLPD+ + Sbjct: 223 NEASRRIKTELLVQMQGFDNSNDKVLVLAATNMPHVLDQAMRRRFDKCIYIPLPDLKARK 282 Query: 260 EIFKIHLRGIHYDVPLSRLAKEAVKRLY-----SGREIANVVKLATMKMLEEMN------ 308 + FKIH+ D P S + V Y SG +IA VK A + + + Sbjct: 283 DTFKIHIG----DTPHSLTEGDFVSLAYQTEGFSGSDIAVCVKDALFQPVRKTQDAKFFI 338 Query: 309 ---------PELSDPLRVST----LKGRDLTTR----PLTLDDFKYAMARIKSPITKSDV 351 E S P + T L + L + P++ DF + R + ++K D+ Sbjct: 339 KADDDTWTPSEQSQPGSIQTTMQELASKGLAAKILLPPISKIDFDEVLVRQRPTVSKKDL 398 Query: 352 KKYERWAKEF 361 YE++ +EF Sbjct: 399 VVYEKFTQEF 408 >gb|AAD38581.1|AF145606_1 (AF145606) BcDNA.GH02678 [Drosophila melanogaster] >gi|7293406|gb|AAF48783.1| (AE003507) BcDNA:GH02678 gene product [Drosophila melanogaster] Length = 442 Score = 177 bits (445), Expect = 1e-43 Identities = 121/351 (34%), Positives = 188/351 (53%), Gaps = 44/351 (12%) Query: 55 EEAKKWEEKAKNVRKRREGKNEYFDKLKA------LIKRSTITWNDIGGLREAKKLIAQA 108 E + K ++ K+ +G + KL++ +I++ + W+D+ GL AK+ + +A Sbjct: 88 ESSAKDDKDKKSDSDDEDGDDPEKKKLQSKLEDAIVIEKPKVQWSDVAGLDAAKEALKEA 147 Query: 109 IGLSIAKSPIE-----PPQGILLFGPPGTGKSLLASAVANSLN-ATFFSVKASDLLSKYF 162 + L I + P +GILLFGPPGTGKS LA AVA N +TFFSV +SDL+SK+ Sbjct: 148 VILPIKFPQLFTGKRIPWKGILLFGPPGTGKSYLAKAVATEANRSTFFSVSSSDLMSKWL 207 Query: 163 GESSKLISALFSLARQLSPSVIFIDEVDSLTMKRV-SLDDAARRMIGTLLAEMDGFKERK 221 GES KL+ LF LARQ PS+IFIDE+DS+ R + +D+ RR+ L +M G Sbjct: 208 GESEKLVKNLFELARQHKPSIIFIDEIDSMCSARSDNENDSVRRIKTEFLVQMQGVGNDT 267 Query: 222 DKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKE 281 D ++VL ATN PW LD A+ R RIY+PLP+ ++ + +FKIHL + + L + Sbjct: 268 DGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEAHARLVMFKIHLGNTTHVLTEQDLKEL 327 Query: 282 AVK-RLYSGREIANVVKLATMKMLEEM----------------NPELSDPLRVSTLKGRD 324 A K YSG +I+ VV+ A M+ + ++ + E+ + L V G Sbjct: 328 AGKTEGYSGADISIVVRDALMEPVRKVQTATHFKRVSGPSPTNHEEIVNDLLVPCSPGDQ 387 Query: 325 --------------LTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 L P+T+ D +++R K + + D+KK ++ ++F Sbjct: 388 GAVEMNWMDVPSDKLFEPPVTMRDMLKSLSRTKPTVNEDDLKKLRKFTEDF 438 >gb|AAF17203.1|AF112215_1 (AF112215) SKD1 protein [Homo sapiens] Length = 437 Score = 177 bits (444), Expect = 2e-43 Identities = 122/325 (37%), Positives = 177/325 (53%), Gaps = 19/325 (5%) Query: 2 YRLQLLQVQKCQEEFERALSL-GHYDKAR-LIALRCAELL---RKIASENLSLSHILLEE 56 Y L Q E F A+ H DKA+ I +C + L K+ S + Sbjct: 25 YEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRAKCVQYLDRAEKLKDYLRSKEEHGKKP 84 Query: 57 AKKWEEKAKNVRKRREGKNEYFDKLK------ALIKRSTITWNDIGGLREAKKLIAQAIG 110 K+ + + K EG N KL+ ++++ I WND+ GL AK+ + +A+ Sbjct: 85 VKENQSEGKGSDSDSEGDNPEKKKLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALKEAVI 144 Query: 111 LSIAKSPI-----EPPQGILLFGPPGTGKSLLASAVANSLN-ATFFSVKASDLLSKYFGE 164 L I + P +GILLFGPPGTGKS LA AVA N +TFFSV +SDL+SK+ GE Sbjct: 145 LPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGE 204 Query: 165 SSKLISALFSLARQLSPSVIFIDEVDSLTMKR-VSLDDAARRMIGTLLAEMDGFKERKDK 223 S KL+ LF LARQ PS+IFIDEVDSL R + +AARR+ L +M G D Sbjct: 205 SEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDG 264 Query: 224 VIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAV 283 +VL ATN PW LD A+ R RIY+PLP+ + ++F++HL +++ + + + A Sbjct: 265 TLVLGATNIPWVLDSAIRRRFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELAR 324 Query: 284 K-RLYSGREIANVVKLATMKMLEEM 307 K YSG +I+ +V+ + M+ + ++ Sbjct: 325 KTEGYSGADISIIVRDSLMQPVRKV 349 >gi|7019569 vacuolar sorting protein 4 [Homo sapiens] >gi|5732691|gb|AAD49227.1|AF159063_1 (AF159063) SKD1-homolog [Homo sapiens] >gi|9885648|gb|AAG01470.1|AF282903_1 (AF282903) vacuolar protein sorting factor 4A [Homo sapiens] Length = 437 Score = 176 bits (443), Expect = 2e-43 Identities = 122/325 (37%), Positives = 177/325 (53%), Gaps = 19/325 (5%) Query: 2 YRLQLLQVQKCQEEFERALSL-GHYDKAR-LIALRCAELL---RKIASENLSLSHILLEE 56 Y L Q E F A+ H DKA+ I +C + L K+ S + Sbjct: 25 YEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRAKCVQYLDRAEKLKDYLRSKEKHGKKP 84 Query: 57 AKKWEEKAKNVRKRREGKNEYFDKLK------ALIKRSTITWNDIGGLREAKKLIAQAIG 110 K+ + + K EG N KL+ ++++ I WND+ GL AK+ + +A+ Sbjct: 85 VKENQSEGKGSDSDSEGDNPEKKKLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALKEAVI 144 Query: 111 LSIAKSPI-----EPPQGILLFGPPGTGKSLLASAVANSLN-ATFFSVKASDLLSKYFGE 164 L I + P +GILLFGPPGTGKS LA AVA N +TFFSV +SDL+SK+ GE Sbjct: 145 LPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGE 204 Query: 165 SSKLISALFSLARQLSPSVIFIDEVDSLTMKR-VSLDDAARRMIGTLLAEMDGFKERKDK 223 S KL+ LF LARQ PS+IFIDEVDSL R + +AARR+ L +M G D Sbjct: 205 SEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDG 264 Query: 224 VIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAV 283 +VL ATN PW LD A+ R RIY+PLP+ + ++F++HL +++ + + + A Sbjct: 265 TLVLGATNIPWVLDSAIRRRFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELAR 324 Query: 284 K-RLYSGREIANVVKLATMKMLEEM 307 K YSG +I+ +V+ + M+ + ++ Sbjct: 325 KTEGYSGADISIIVRDSLMQPVRKV 349 >gi|11430565 similar to vacuolar sorting protein 4 (H. sapiens) [Homo sapiens] Length = 479 Score = 176 bits (443), Expect = 2e-43 Identities = 122/325 (37%), Positives = 177/325 (53%), Gaps = 19/325 (5%) Query: 2 YRLQLLQVQKCQEEFERALSL-GHYDKAR-LIALRCAELL---RKIASENLSLSHILLEE 56 Y L Q E F A+ H DKA+ I +C + L K+ S + Sbjct: 67 YEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRAKCVQYLDRAEKLKDYLRSKEKHGKKP 126 Query: 57 AKKWEEKAKNVRKRREGKNEYFDKLK------ALIKRSTITWNDIGGLREAKKLIAQAIG 110 K+ + + K EG N KL+ ++++ I WND+ GL AK+ + +A+ Sbjct: 127 VKENQSEGKGSDSDSEGDNPEKKKLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALKEAVI 186 Query: 111 LSIAKSPI-----EPPQGILLFGPPGTGKSLLASAVANSLN-ATFFSVKASDLLSKYFGE 164 L I + P +GILLFGPPGTGKS LA AVA N +TFFSV +SDL+SK+ GE Sbjct: 187 LPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGE 246 Query: 165 SSKLISALFSLARQLSPSVIFIDEVDSLTMKR-VSLDDAARRMIGTLLAEMDGFKERKDK 223 S KL+ LF LARQ PS+IFIDEVDSL R + +AARR+ L +M G D Sbjct: 247 SEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDG 306 Query: 224 VIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAV 283 +VL ATN PW LD A+ R RIY+PLP+ + ++F++HL +++ + + + A Sbjct: 307 TLVLGATNIPWVLDSAIRRRFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELAR 366 Query: 284 K-RLYSGREIANVVKLATMKMLEEM 307 K YSG +I+ +V+ + M+ + ++ Sbjct: 367 KTEGYSGADISIIVRDSLMQPVRKV 391 >sp|Q09803|SKD1_SCHPO SUPRESSOR PROTEIN OF BEM1/BED5 DOUBLE MUTANTS >gi|2130392|pir||S62461 probable AAA-family ATPase, supressor protein - fission yeast (Schizosaccharomyces pombe) >gi|7492345|pir||T38572 probable AAA-family ATPase - fission yeast (Schizosaccharomyces pombe) >gi|496311|gb|AAA35347.1| (L33456) supressor protein [Schizosaccharomyces pombe] >gi|1019404|emb|CAA91171.1| (Z54354) putative AAA-family ATPase [Schizosaccharomyces pombe] Length = 432 Score = 176 bits (442), Expect = 3e-43 Identities = 109/310 (35%), Positives = 172/310 (55%), Gaps = 33/310 (10%) Query: 84 LIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPI-----EPPQGILLFGPPGTGKSLLA 138 L+++ + W+DI GL AK+ + + + L I + +P GILL+GPPGTGKS LA Sbjct: 120 LVEKPNVRWDDIAGLENAKEALKETVLLPIKLPQLFSHGRKPWSGILLYGPPGTGKSYLA 179 Query: 139 SAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVS 198 AVA +TFFS+ +SDL+SK+ GES +L+ LF +AR+ PS+IFIDE+DSL R Sbjct: 180 KAVATEAGSTFFSISSSDLVSKWMGESERLVRQLFEMAREQKPSIIFIDEIDSLCGSRSE 239 Query: 199 LDDAARRMIGT-LLAEMDGFKERKDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNS 257 + + R I T L +M+G + + V+VL ATN PW LD A+ R RIY+PLP+ ++ Sbjct: 240 GESESSRRIKTEFLVQMNGVGKDESGVLVLGATNIPWTLDSAIRRRFEKRIYIPLPNAHA 299 Query: 258 AVEIFKIHLRGIHYDVPLSRLAKEAVKRL--YSGREIANVVKLATMK------------- 302 +F++++ I ++ S+ KE K YSG +I+ VV+ A M+ Sbjct: 300 RARMFELNVGKIPSEL-TSQDFKELAKMTDGYSGSDISIVVRDAIMEPVRRIHTATHFKE 358 Query: 303 ---------MLEEMNPELSDPLRVSTLK--GRDLTTRPLTLDDFKYAMARIKSPITKSDV 351 ++ +P D S L+ D+ LT+ DF A+ ++K + D+ Sbjct: 359 VYDNKSNRTLVTPCSPGDPDAFESSWLEVNPEDIMEPKLTVRDFYSAVRKVKPTLNAGDI 418 Query: 352 KKYERWAKEF 361 +K+ ++ K+F Sbjct: 419 EKHTQFTKDF 428 >gb|AAD42971.1|AF155740_1 (AF155740) vacuolar sorting protein 4 [Homo sapiens] Length = 432 Score = 175 bits (440), Expect = 6e-43 Identities = 121/325 (37%), Positives = 177/325 (54%), Gaps = 19/325 (5%) Query: 2 YRLQLLQVQKCQEEFERALSL-GHYDKAR-LIALRCAELL---RKIASENLSLSHILLEE 56 Y L Q E F A+ H DKA+ I +C + L K+ S + Sbjct: 20 YEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRAKCVQYLDRAEKLKDYLRSKEKHGKKP 79 Query: 57 AKKWEEKAKNVRKRREGKNEYFDKLK------ALIKRSTITWNDIGGLREAKKLIAQAIG 110 K+ + + K EG N KL+ ++++ I WND+ GL AK+ + +A+ Sbjct: 80 VKENQSEGKGSDSDSEGDNPEKKKLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALKEAVI 139 Query: 111 LSIAKSPI-----EPPQGILLFGPPGTGKSLLASAVANSLN-ATFFSVKASDLLSKYFGE 164 L I + P +GILLFGPPGTGKS LA AVA N +TFFSV +SDL+SK+ GE Sbjct: 140 LPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGE 199 Query: 165 SSKLISALFSLARQLSPSVIFIDEVDSLTMKR-VSLDDAARRMIGTLLAEMDGFKERKDK 223 S KL+ LF LARQ PS+IFIDEVDSL R + +AARR+ L +M G D Sbjct: 200 SEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDG 259 Query: 224 VIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAV 283 +VL ATN PW LD A+ + RIY+PLP+ + ++F++HL +++ + + + A Sbjct: 260 TLVLGATNIPWVLDSAIRRKFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELAR 319 Query: 284 K-RLYSGREIANVVKLATMKMLEEM 307 K YSG +I+ +V+ + M+ + ++ Sbjct: 320 KTEGYSGADISIIVRDSLMQPVRKV 344 >gb|AAC73040.1| (AC005824) putative AAA-type ATPase [Arabidopsis thaliana] Length = 435 Score = 175 bits (439), Expect = 7e-43 Identities = 111/329 (33%), Positives = 179/329 (53%), Gaps = 39/329 (11%) Query: 71 REGKNEYFDKLKALI------KRSTITWNDIGGLREAKKLIAQAIGLSIAKSPI-----E 119 ++G++ KL+A + ++ I W+D+ GL AK+ + +A+ L + Sbjct: 104 KDGEDPEQSKLRAGLNSAIVREKPNIKWSDVAGLESAKQALQEAVILPVKFPQFFTGKRR 163 Query: 120 PPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQL 179 P + LL+GPPGTGKS LA AVA ++TFFSV +SDL+SK+ GES KL+S LF +AR+ Sbjct: 164 PWRAFLLYGPPGTGKSYLAKAVATEADSTFFSVSSSDLVSKWMGESEKLVSNLFEMARES 223 Query: 180 SPSVIFIDEVDSL--TMKRVSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLD 237 +PS+IF+DE+DSL T + +A+RR+ LL +M G +KV+VL ATN P+ LD Sbjct: 224 APSIIFVDEIDSLCGTRGEGNESEASRRIKTELLVQMQGVGHNDEKVLVLAATNTPYALD 283 Query: 238 EAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVK-RLYSGREIANVV 296 +A+ R RIY+PLP+ + +FK+HL +++ K +SG +++ V Sbjct: 284 QAIRRRFDKRIYIPLPEAKARQHMFKVHLGDTPHNLTEPDFEYLGQKTEGFSGSDVSVCV 343 Query: 297 KLATMKMLEEMNPEL---------------SDPLRVSTLKGRDLTTR---------PLTL 332 K + + + + P + T +DL T+ P+T Sbjct: 344 KDVLFEPVRKTQDAMFFFKSPDGTWMPCGPRHPGAIQTTM-QDLATKGLAEKIIPPPITR 402 Query: 333 DDFKYAMARIKSPITKSDVKKYERWAKEF 361 DF+ +AR + ++KSD+ +ER+ +EF Sbjct: 403 TDFEKVLARQRPTVSKSDLDVHERFTQEF 431 >gb|AAK40746.1| AAA family ATPase [Sulfolobus solfataricus] Length = 769 Score = 174 bits (436), Expect = 2e-42 Identities = 111/296 (37%), Positives = 163/296 (54%), Gaps = 31/296 (10%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKSLLASAVAN 143 + W DIGGL EAK+ + +A+ + K I PP+GILLFGPPGTGK++LA AVA Sbjct: 473 VKWEDIGGLEEAKQQLREAVEWPLKFPEMFEKLGIRPPKGILLFGPPGTGKTMLAKAVAT 532 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDA- 202 A F +V+ ++LSK+ GES K + +F ARQ +P VIF DE+DS+ R D+ Sbjct: 533 ESGANFIAVRGPEILSKWVGESEKAVREIFRRARQTAPCVIFFDEIDSIAPMRGFTHDSG 592 Query: 203 -ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAV 259 R++ LL+EMDG + ++V+V+ ATN P LD A+L R IYVP PD + + Sbjct: 593 VTERIVNQLLSEMDGI-QSLNRVVVIAATNRPDILDPALLRPGRFDRLIYVPPPDEKARI 651 Query: 260 EIFKIHLRGIHYD--VPLSRLAKEAVKRLYSGREIANVVKLATMKMLEE----------- 306 EI KI+ R + D V L LAK+ Y+G +I + + TMK+L + Sbjct: 652 EILKIYTRTLPIDSSVNLEELAKKL--EGYTGADIEALARETTMKVLRQKYYDCLNKAKK 709 Query: 307 --MNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKE 360 + E +D S + ++ +T+ DF M + +TK+D+ +YE KE Sbjct: 710 ECKDQECTDKTIKSCMSNLEI---KITMQDFLDTMKIVTPSLTKADIMRYENMVKE 762 Score = 147 bits (367), Expect = 2e-34 Identities = 92/270 (34%), Positives = 148/270 (54%), Gaps = 14/270 (5%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 +TW DIG L + K+ I + + L + IEPP+G+LL+GPPG GK+LLA A+AN Sbjct: 198 VTWEDIGDLEDVKEKIREIVELPMRHPEVFQHLGIEPPKGVLLYGPPGVGKTLLARALAN 257 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL-DDA 202 + A F S+ +++SK++GES + + +F A + SP++IFIDE+D++ KR + + Sbjct: 258 EIGAYFTSINGPEIMSKFYGESEQRLREIFEEAEKNSPAIIFIDEIDAIAPKREEVTGEV 317 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVE 260 +R++ LL MDG K R KVIV+ ATN P +D A+ R I + PD + E Sbjct: 318 EKRVVAQLLTLMDGIKGR-GKVIVIGATNRPDAVDPALRRPGRFDREIEIRPPDAKARKE 376 Query: 261 IFKIHLRG--IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 I ++H R + DV L +++++ Y+G ++A + + A M L E L Sbjct: 377 ILQVHTRNMPLAEDVDLDKISEQT--HGYTGADLAALAREAAMNALRRFINERKINLEQE 434 Query: 319 TLKGRDLTTRPLTLDDFKYAMARIKSPITK 348 + L +T+ DF AM I+ + + Sbjct: 435 QIPVDVLKELKVTMQDFIDAMKFIQPTLLR 464 >gb|AAF76434.1|AC015445_1 (AC015445) Contains similarity to p60 katanin from Chlamydomonas reinhardtii gb|AF205377 and contains an AAA domain PF|00004. [Arabidopsis thaliana] Length = 627 Score = 174 bits (436), Expect = 2e-42 Identities = 111/323 (34%), Positives = 173/323 (53%), Gaps = 22/323 (6%) Query: 53 LLEEAKKWEEKAKNVRKRREGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLS 112 L + + K + KN+ K +N F + + DIG L + KK + + + L Sbjct: 300 LEDNSLKPSQNLKNIAKDEYERN--FVSAVVAPGEIGVKFEDIGALEDVKKALNELVILP 357 Query: 113 IAKSPI-------EPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGES 165 + + + P +GILLFGPPGTGK+LLA A+A A F S+ S L SK+FG++ Sbjct: 358 MRRPELFARGNLLRPCKGILLFGPPGTGKTLLAKALATEAGANFISITGSTLTSKWFGDA 417 Query: 166 SKLISALFSLARQLSPSVIFIDEVDSLTMKR--VSLDDAARRMIGTLLAEMDGFKER-KD 222 KL ALFS A +L+P +IF+DE+DSL R S +A RRM +A DG + + Sbjct: 418 EKLTKALFSFATKLAPVIIFVDEIDSLLGARGGSSEHEATRRMRNEFMAAWDGLRSKDSQ 477 Query: 223 KVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHL--RGIHYDVPLSRLAK 280 ++++L ATN P+DLD+A++ RLP RIYV LPD + ++I KI L + D +LAK Sbjct: 478 RILILGATNRPFDLDDAVIRRLPRRIYVDLPDAENRLKILKIFLTPENLESDFQFEKLAK 537 Query: 281 EAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMA 340 E YSG ++ N+ A + ++E+ E R G R L+LDDF + A Sbjct: 538 ET--EGYSGSDLKNLCIAAAYRPVQELLQEEQKGARAEASPG----LRSLSLDDFIQSKA 591 Query: 341 RIKSPIT--KSDVKKYERWAKEF 361 ++ + + + + +W +++ Sbjct: 592 KVSPSVAYDATTMNELRKWNEQY 614 >gb|AAK40524.1| AAA family ATPase [Sulfolobus solfataricus] Length = 769 Score = 173 bits (435), Expect = 2e-42 Identities = 107/295 (36%), Positives = 169/295 (57%), Gaps = 27/295 (9%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKSLLASAVAN 143 + W DIGGL E K+ + + + + S IEPP+GILLFGPPGTGK++LA AVA Sbjct: 462 VKWTDIGGLEEIKEELKEVVEYPLKYSELYQNSGIEPPKGILLFGPPGTGKTMLAKAVAT 521 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLT-MKRVSLDD- 201 A F +V+ ++LSK+ GES K + +F AR +P+VIF DE+DS+ ++ +S D Sbjct: 522 ESGANFIAVRGPEILSKWVGESEKAVREIFRKARMYAPAVIFFDEIDSIAPIRGISYDSG 581 Query: 202 AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAV 259 R++ LLAEMDG E+ + V+V+ ATN P LD A+L R IYVP PD + Sbjct: 582 VTERIVNQLLAEMDGI-EKLENVVVIAATNRPDILDPALLRPGRFEKLIYVPPPDKRART 640 Query: 260 EIFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMN----PELSD 313 EI K+H R I D+ L +A++ Y+G ++A +V+ ATM+ + E + ++ Sbjct: 641 EILKVHTRNIALGEDISLEDVAEKT--EGYTGADLAALVREATMRAIRESMKICIDKTNE 698 Query: 314 PLRVSTLKGRDLTTR--------PLTLDDFKYAMARIKSPITKSDVKKYERWAKE 360 + + + RD T + ++L F+ AM ++K +T+ ++ Y+ W ++ Sbjct: 699 NCKPTDAECRDKTMKECMKVNGVKVSLRHFEEAMRKVKPSVTQDMLQFYQNWVEK 753 Score = 149 bits (373), Expect = 4e-35 Identities = 90/264 (34%), Positives = 150/264 (56%), Gaps = 16/264 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKSLLASAVAN 143 +T+ DIGG++ + + + + L + + IEPP+GILL+GPPG GK+LLA A+AN Sbjct: 189 VTYEDIGGMKNIIEKVRELVELPLRHPELFKRLGIEPPKGILLYGPPGVGKTLLAKAIAN 248 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVS-LDDA 202 +A F S+ +++SK++GES + + +F A++ +P++IF+DE+D++ KR + + Sbjct: 249 ETDAYFTSINGPEIMSKFYGESEQRLREIFEDAKKHAPAIIFVDEIDAIAPKRDEVIGEV 308 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVE 260 RR++ LL MDG E + VIV+ ATN P +D A+ R I +PLPD +E Sbjct: 309 ERRVVAQLLTLMDGL-ENRGNVIVIAATNRPSAVDPALRRPGRFDREIEIPLPDKQGRLE 367 Query: 261 IFKIHLRG--IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 I +IH R + DV L +LA + Y+G +++ +V+ A M L P++ L Sbjct: 368 ILQIHTRNMPLSKDVDLEKLAD--MTHGYTGADLSALVREAAMNSLRRYLPKID--LNQD 423 Query: 319 TLKGRDLTTRPLTLDDFKYAMARI 342 + L + + ++DF A I Sbjct: 424 KIPPEILESMEVKMEDFINAFKEI 447 >dbj|BAA87866.1| (AB018433) Pk-cdcA [Pyrococcus kodakaraensis] Length = 835 Score = 173 bits (435), Expect = 2e-42 Identities = 123/350 (35%), Positives = 189/350 (53%), Gaps = 33/350 (9%) Query: 26 DKARLIALRCAELLRKIASENLSLSHILLEEAKKWEEKAKNVRKRREGKNEYFDKLK--- 82 D A L +LR++ E I E+ + E + +R RR+ ++++ LK Sbjct: 475 DLAALAREAAMVVLRRLIKEG----KISPEQERIPPEVLQELRVRRD---DFYEALKMVE 527 Query: 83 ------ALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPP 130 LI+ + W DIGGL + K+ + +A+ + + IEPP+GILL+GPP Sbjct: 528 PSALREVLIEVPNVRWEDIGGLEDVKQELREAVEWPLKYPKAFERLGIEPPKGILLYGPP 587 Query: 131 GTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVD 190 GTGK+LLA AVAN A F +++ ++LSK+ GE+ K I +F ARQ +P+V+FIDE+D Sbjct: 588 GTGKTLLAKAVANESQANFIAIRGPEVLSKWVGETEKRIREIFRKARQAAPTVVFIDEID 647 Query: 191 SLTMKRVSLDD-AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIR 247 ++ R S D R+I LL EMDG +E V+V+ ATN P +D A+L R Sbjct: 648 AIAPARGSEGDRVTDRLINQLLTEMDGIQENSG-VVVIGATNRPDIIDPALLRPGRFDRL 706 Query: 248 IYVPLPDVNSAVEIFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLE 305 I VP PD + +EIFK+H R + DV L LAK+ Y+G +IA +V+ A + + Sbjct: 707 ILVPAPDEKARLEIFKVHTRRVPLAGDVDLRELAKKT--EGYTGADIAALVREAALIAMR 764 Query: 306 EMNPELSDPLRVSTLKGRDLTTR-PLTLDDFKYAMARIKSPITKSDVKKY 354 + EL P V + + R ++ DF+ AM ++K +T ++ Y Sbjct: 765 RIMREL--PREVVESESEEFLERLKVSKKDFEMAMKKVKPSVTPYMMEYY 812 Score = 146 bits (364), Expect = 5e-34 Identities = 87/207 (42%), Positives = 126/207 (60%), Gaps = 15/207 (7%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFGPPGTGKSLLASAVA 142 +T+ DIGGL +A + I + + L + K P IEPP+G+LL+GPPGTGK+LLA AVA Sbjct: 206 VTYEDIGGLSDAIQKIREMVELPL-KHPELFERLGIEPPKGVLLYGPPGTGKTLLAKAVA 264 Query: 143 NSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVS-LDD 201 N NA F ++ +++SK++GES + + +F A + +PS+IFIDE+D++ KR + + Sbjct: 265 NEANAHFIAINGPEIMSKFYGESEERLREIFKEAEENAPSIIFIDEIDAIAPKREEVVGE 324 Query: 202 AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAV 259 +R++ LL MDG K R KVIV+ ATN P LD A+ R I V +PD Sbjct: 325 VEKRVVSQLLTLMDGLKSR-GKVIVIAATNRPDALDPALRRPGRFDREIEVGVPDKQGRK 383 Query: 260 EIFKIHLRGIHYDVPLSRLAKEAVKRL 286 EI +IH RG+ + KEAV R+ Sbjct: 384 EILQIHTRGMPLEPDYD---KEAVLRV 407 >gi|6325183 Yta6p [Saccharomyces cerevisiae] >gi|2133218|pir||S61113 YTA6 protein - yeast (Saccharomyces cerevisiae) >gi|1147619|gb|AAB68264.1| (U41849) Yta6p [Saccharomyces cerevisiae] Length = 754 Score = 173 bits (434), Expect = 3e-42 Identities = 106/300 (35%), Positives = 165/300 (54%), Gaps = 34/300 (11%) Query: 84 LIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPI-----EPPQGILLFGPPGTGKSLLA 138 L+ + W DI GLR AK + +A+ + + EP +G+LLFGPPGTGK+++A Sbjct: 462 LVTDEKVYWEDIAGLRNAKNSLKEAVVYPFLRPDLFKGLREPVRGMLLFGPPGTGKTMIA 521 Query: 139 SAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDS-LTMKRV 197 AVA N+TFFSV AS LLSKY GES KL+ ALF +A++LSPS+IFIDE+DS LT + Sbjct: 522 KAVATESNSTFFSVSASSLLSKYLGESEKLVRALFYMAKKLSPSIIFIDEIDSMLTARSD 581 Query: 198 SLDDAARRMIGTLLAEMDGFKER-----------KDKVIVLTATNAPWDLDEAMLSRLPI 246 + ++++RR+ LL + +V+VL ATN PW +D+A R Sbjct: 582 NENESSRRIKTELLIQWSSLSSATAQSEDRNNTLDSRVLVLGATNLPWAIDDAARRRFSR 641 Query: 247 RIYVPLPDVNSAVEIFKIHLRGI--HYDVPLSRLAKEAVKRL---YSGREIANVVKLATM 301 ++Y+PLPD + + HL+ + L L E + + +SG ++ ++ K A M Sbjct: 642 KLYIPLPDYETRL----YHLKRLMAKQKNSLQDLDYELITEMTEGFSGSDLTSLAKEAAM 697 Query: 302 KMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 + + +L D L + R + + DF+ A+ IK ++ ++KYE W+ +F Sbjct: 698 EPIR----DLGDKLMFADFD----KIRGIEIKDFQNALLTIKKSVSSESLQKYEEWSSKF 749 >dbj|BAB01094.1| (AB026649) gene_id:MOJ10.20~unknown protein [Arabidopsis thaliana] Length = 694 Score = 173 bits (433), Expect = 4e-42 Identities = 110/321 (34%), Positives = 172/321 (53%), Gaps = 42/321 (13%) Query: 62 EKAKNVRKR--REGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPI- 118 EK +N+ R NE D+ + W+DI GL AKK + + + + + I Sbjct: 390 EKLRNLEPRLIEHVSNEIMDR------DPNVRWDDIAGLEHAKKCVTEMVIWPLLRPDIF 443 Query: 119 ----EPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFS 174 P +G+LLFGPPGTGK+++ A+A ATFF + AS L SK+ GE KL+ ALF Sbjct: 444 KGCRSPGKGLLLFGPPGTGKTMIGKAIAGEAKATFFYISASSLTSKWIGEGEKLVRALFG 503 Query: 175 LARQLSPSVIFIDEVDSLTMKRVS--LDDAARRMIGTLLAEMDGFKERKDKVIVLTATNA 232 +A P+VIF+DE+DSL +R S +++RR+ L EM+GF ++++++ ATN Sbjct: 504 VASCRQPAVIFVDEIDSLLSQRKSDGEHESSRRLKTQFLIEMEGFDSGSEQILLIGATNR 563 Query: 233 PWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRL------ 286 P +LDEA RL R+Y+PLP + I + L+ L L+ + + + Sbjct: 564 PQELDEAARRRLTKRLYIPLPSSEARAWIIQNLLK----KDGLFTLSDDDMNIICNLTEG 619 Query: 287 YSGREIANVVKLATMKMLEEMNPELSDPLRVSTLKGRDLTT------RPLTLDDFKYAMA 340 YSG ++ N+VK ATM PLR + +G D+T R +TL DFK A+ Sbjct: 620 YSGSDMKNLVKDATM-----------GPLREALKRGIDITNLTKDDMRLVTLQDFKDALQ 668 Query: 341 RIKSPITKSDVKKYERWAKEF 361 ++ ++++++ YE W +F Sbjct: 669 EVRPSVSQNELGIYENWNNQF 689 >pir||D75046 transitional endoplasmic reticulum atpase PAB1478 - Pyrococcus abyssi (strain Orsay) >gi|5458778|emb|CAB50265.1| (AJ248287) TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE [Pyrococcus abyssi] Length = 840 Score = 172 bits (432), Expect = 5e-42 Identities = 109/288 (37%), Positives = 163/288 (55%), Gaps = 16/288 (5%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKS 135 + LI+ + W+DIGGL + K+ + +A+ + + I PP+G+LL+GPPGTGK+ Sbjct: 536 EVLIEVPNVHWDDIGGLEDVKQELREAVEWPLKYPKAFKRLGITPPKGVLLYGPPGTGKT 595 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 LLA AVA A F +++ ++LSK+ GES K I +F ARQ SP++IFIDE+D++ Sbjct: 596 LLAKAVATESQANFIAIRGPEVLSKWVGESEKRIREIFRKARQASPAIIFIDEIDAIAPA 655 Query: 196 RVSL--DDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVP 251 R + + R+I LL EMDG E V+V+ ATN P LD A+L R I VP Sbjct: 656 RGTAEGEKVTDRIINQLLTEMDGLVENSG-VVVIAATNRPDILDPALLRPGRFDRLILVP 714 Query: 252 LPDVNSAVEIFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNP 309 PD + EIFK+H RG+ DV L LA+ Y+G +IA V + A M L Sbjct: 715 APDEKARFEIFKVHTRGMPLADDVDLKELARRT--EGYTGADIAAVCREAAMNALRRAVA 772 Query: 310 ELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERW 357 +LS P + + L + +T DF+ A+ ++K +TK ++ Y ++ Sbjct: 773 KLS-PEELEEESEKFLKSLIVTRKDFEVALKKVKPSVTKYMMEYYRQF 819 Score = 148 bits (370), Expect = 9e-35 Identities = 93/243 (38%), Positives = 141/243 (57%), Gaps = 21/243 (8%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFGPPGTGKSLLASAVA 142 +T+ DIGGL+EA + I + + L + K P IEPP+G+LL+GPPGTGK+LLA AVA Sbjct: 209 VTYEDIGGLKEAIEKIREMVELPL-KHPELFERLGIEPPKGVLLYGPPGTGKTLLAKAVA 267 Query: 143 NSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVS-LDD 201 N NA F ++ +++SKY+GES + + +F A + +P++IFIDE+D++ KR + + Sbjct: 268 NEANAYFIAINGPEIMSKYYGESEERLREIFKEAEENAPAIIFIDEIDAIAPKREEVVGE 327 Query: 202 AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAV 259 +R++ LL MDG K R KVIV+ ATN P LD A+ R I V +PD Sbjct: 328 VEKRVVSQLLTLMDGLKSR-GKVIVIAATNRPDALDPALRRPGRFDREIEVGVPDKQGRK 386 Query: 260 EIFKIHLRGIHYDVPLSR-LAKEAVKRL-----YSGREIANVVKLATMKMLEEMNPELSD 313 EI +IH RG+ + + +A+K L + +I +++ + EE E+ D Sbjct: 387 EILQIHTRGMPIEPDFEKETVIKALKELEKDDRFDKEKIKKIIEKVSKAKSEE---EIKD 443 Query: 314 PLR 316 LR Sbjct: 444 ILR 446 >pir||D72613 probable transitional endoplasmic reticulum ATPase APE1367 - Aeropyrum pernix (strain K1) >gi|5105048|dbj|BAA80362.1| (AP000061) 726aa long hypothetical transitional endoplasmic reticulum ATPase [Aeropyrum pernix] Length = 726 Score = 172 bits (432), Expect = 5e-42 Identities = 109/284 (38%), Positives = 159/284 (55%), Gaps = 33/284 (11%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKSLLASAVAN 143 + W+DIGGL EAK+ + +A+ + K I PP+G+LLFGPPGTGK+LLA AVA Sbjct: 456 VRWSDIGGLEEAKQALREAVEWPLKHPEIFEKMGIRPPRGVLLFGPPGTGKTLLAKAVAT 515 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDAA 203 A F +V+ ++LSK+ GES + I +F ARQ +P+V+F DE+D++ R + D + Sbjct: 516 ESGANFIAVRGPEILSKWVGESERAIRKIFERARQAAPAVVFFDEIDAIAPARGARFDTS 575 Query: 204 ---RRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSA 258 R++ +LAEMDG + + V+V+ ATN P LD A+L R IYVP PD + Sbjct: 576 GVTDRIVNQMLAEMDGIQPLSN-VVVIGATNRPDILDPALLRPGRFDRLIYVPPPDKEAR 634 Query: 259 VEIFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLR 316 EIFKIH + + DV L +LA+ + Y+G +I VV+ A M L E Sbjct: 635 KEIFKIHTKKVPLGEDVDLEKLAE--MTEGYTGADIEAVVREAVMAKLRE---------- 682 Query: 317 VSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKE 360 L + + F A+ ++ +TK D+ +YER AKE Sbjct: 683 -------KLEVGKVEMRHFLEALKKVPPSLTKEDILRYERLAKE 719 Score = 167 bits (418), Expect = 2e-40 Identities = 108/298 (36%), Positives = 164/298 (54%), Gaps = 19/298 (6%) Query: 63 KAKNVRKRREGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP----- 117 +A V R + E ++L+ + K +TW DIG L EAK+ I + + L + K P Sbjct: 157 EATEVEIREKPVREEIERLRGVPK---VTWEDIGDLEEAKERIREIVELPM-KHPEIFKH 212 Query: 118 --IEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSL 175 IEPP+GILL+GPPGTGK+LLA A+AN + A F S+ +++SKY+GES + + +F Sbjct: 213 LGIEPPKGILLYGPPGTGKTLLAKALANEIGAYFISINGPEIMSKYYGESEQRLREIFKE 272 Query: 176 ARQLSPSVIFIDEVDSLTMKRVSL-DDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPW 234 A + +PS+IFIDE+D++ KR + + +R++ LL MDG KER +VIV+ ATN P Sbjct: 273 AEENAPSIIFIDEIDAIAPKREEVTGEVEKRVVAQLLTLMDGLKER-GRVIVIGATNRPD 331 Query: 235 DLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRG--IHYDVPLSRLAKEAVKRLYSGR 290 +D A+ R I + PD + EI K+H R + DV L +LA+ + Y+G Sbjct: 332 AIDPALRRPGRFDREIEIRPPDKRARAEILKVHTRNMPLAEDVDLDKLAE--MTHGYTGA 389 Query: 291 EIANVVKLATMKMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITK 348 ++A + K A M L E + L +T+ DF AM I+ + + Sbjct: 390 DLAALAKEAAMAALRRFIREGKINFEAKEIPATVLKELKVTMKDFMEAMKMIRPTLIR 447 >gi|6320887 member of the AAA ATPase family of proteins; Sap1p [Saccharomyces cerevisiae] >gi|731461|sp|P39955|SAP1_YEAST SAP1 PROTEIN >gi|1077655|pir||S50550 SIN1-associated protein SAP1 - yeast (Saccharomyces cerevisiae) >gi|603280|gb|AAB64582.1| (U18796) Yer047cp [Saccharomyces cerevisiae] Length = 897 Score = 171 bits (430), Expect = 8e-42 Identities = 108/320 (33%), Positives = 169/320 (52%), Gaps = 41/320 (12%) Query: 71 REGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPI-----EPPQGIL 125 R+ + F ++ ++ + W+DI GL AK + +A+ + + EP +G+L Sbjct: 585 RQAAKQIFAEI--VVHGDEVHWDDIAGLESAKYSLKEAVVYPFLRPDLFRGLREPVRGML 642 Query: 126 LFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIF 185 LFGPPGTGK++LA AVA ++TFFS+ AS L SKY GES KL+ ALF++A++LSPS+IF Sbjct: 643 LFGPPGTGKTMLARAVATESHSTFFSISASSLTSKYLGESEKLVRALFAIAKKLSPSIIF 702 Query: 186 IDEVDSLTMKR--VSLDDAARRMIGTLLAEMDGFK-------------------ERKDKV 224 +DE+DS+ R + ++++RR+ L + E +V Sbjct: 703 VDEIDSIMGSRNNENENESSRRIKNEFLVQWSSLSSAAAGSNKSNTNNSDTNGDEDDTRV 762 Query: 225 IVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFK---IHLRGIHYDVPLSRLAKE 281 +VL ATN PW +DEA R R Y+PLP+ + FK H + + L K Sbjct: 763 LVLAATNLPWSIDEAARRRFVRRQYIPLPEDQTRHVQFKKLLSHQKHTLTESDFDELVK- 821 Query: 282 AVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMAR 341 + YSG +I ++ K A M L ++ +L + R RP+ L DFK ++ Sbjct: 822 -ITEGYSGSDITSLAKDAAMGPLRDLGDKLLETERE--------MIRPIGLVDFKNSLVY 872 Query: 342 IKSPITKSDVKKYERWAKEF 361 IK +++ + KYE+WA +F Sbjct: 873 IKPSVSQDGLVKYEKWASQF 892 >emb|CAB60143.1| (AJ246002) spastin protein orthologue [Mus musculus] Length = 504 Score = 171 bits (429), Expect = 1e-41 Identities = 113/313 (36%), Positives = 173/313 (55%), Gaps = 27/313 (8%) Query: 67 VRKRREGKN--EYFDKLKALIKR------STITWNDIGGLREAKKLIAQAIGLSIAKSPI 118 VRK+++ KN L LI + + ++DI G AK+ + + + L + + Sbjct: 196 VRKKKDLKNFRNVDSNLANLIMNEIVDNGTAVKFDDIAGQELAKQALQEIVILPSLRPEL 255 Query: 119 -----EPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALF 173 P +G+LLFGPPG GK++LA AVA NATFF++ A+ L SKY GE KL+ ALF Sbjct: 256 FTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALF 315 Query: 174 SLARQLSPSVIFIDEVDSLTM-KRVSLDDAARRMIGTLLAEMDGFKER-KDKVIVLTATN 231 ++AR+L PS+IFIDEVDSL +R DA+RR+ L E DG + D+V+V+ ATN Sbjct: 316 AVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSAGDDRVLVMGATN 375 Query: 232 APWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRL---YS 288 P +LDEA+L R R+YV LP+ + + + K L PL++ + R+ YS Sbjct: 376 RPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLL--CKQGSPLTQKELAQLARMTDGYS 433 Query: 289 GREIANVVKLATMKMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITK 348 G ++ + K A + + E+ PE + S + R + L DF ++ +IK ++ Sbjct: 434 GSDLTALAKDAALGPIRELKPEQVKNMSASEM-------RNIRLSDFTESLKKIKRSVSP 486 Query: 349 SDVKKYERWAKEF 361 ++ Y RW K+F Sbjct: 487 QTLEAYIRWNKDF 499 >gi|7662478 spastin [Homo sapiens] >gi|5689503|dbj|BAA83035.1| (AB029006) KIAA1083 protein [Homo sapiens] Length = 584 Score = 170 bits (426), Expect = 2e-41 Identities = 105/284 (36%), Positives = 162/284 (56%), Gaps = 19/284 (6%) Query: 88 STITWNDIGGLREAKKLIAQAIGLSIAKSPI-----EPPQGILLFGPPGTGKSLLASAVA 142 + + ++DI G AK+ + + + L + + P +G+LLFGPPG GK++LA AVA Sbjct: 305 TAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVA 364 Query: 143 NSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTM-KRVSLDD 201 NATFF++ A+ L SKY GE KL+ ALF++AR+L PS+IFIDEVDSL +R D Sbjct: 365 AESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHD 424 Query: 202 AARRMIGTLLAEMDGFKER-KDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVE 260 A+RR+ L E DG + D+V+V+ ATN P +LDEA+L R R+YV LP+ + + Sbjct: 425 ASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLL 484 Query: 261 IFKIHLRGIHYDVPLSRLAKEAVKRL---YSGREIANVVKLATMKMLEEMNPELSDPLRV 317 + K L PL++ + R+ YSG ++ + K A + + E+ PE + Sbjct: 485 LLKNLL--CKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSA 542 Query: 318 STLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 S + R + L DF ++ +IK ++ ++ Y RW K+F Sbjct: 543 SEM-------RNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKDF 579 >emb|CAB60141.1| (AJ246001) spastin protein [Homo sapiens] >gi|6273493|emb|CAB60208.1| (AJ246003) spastin protein [Homo sapiens] Length = 616 Score = 170 bits (426), Expect = 2e-41 Identities = 105/284 (36%), Positives = 162/284 (56%), Gaps = 19/284 (6%) Query: 88 STITWNDIGGLREAKKLIAQAIGLSIAKSPI-----EPPQGILLFGPPGTGKSLLASAVA 142 + + ++DI G AK+ + + + L + + P +G+LLFGPPG GK++LA AVA Sbjct: 337 TAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVA 396 Query: 143 NSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTM-KRVSLDD 201 NATFF++ A+ L SKY GE KL+ ALF++AR+L PS+IFIDEVDSL +R D Sbjct: 397 AESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHD 456 Query: 202 AARRMIGTLLAEMDGFKER-KDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVE 260 A+RR+ L E DG + D+V+V+ ATN P +LDEA+L R R+YV LP+ + + Sbjct: 457 ASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLL 516 Query: 261 IFKIHLRGIHYDVPLSRLAKEAVKRL---YSGREIANVVKLATMKMLEEMNPELSDPLRV 317 + K L PL++ + R+ YSG ++ + K A + + E+ PE + Sbjct: 517 LLKNLL--CKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSA 574 Query: 318 STLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 S + R + L DF ++ +IK ++ ++ Y RW K+F Sbjct: 575 SEM-------RNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKDF 611 >pir||F75154 cell division control protein 48, aaa family (cdc48-1) PAB2086 - Pyrococcus abyssi (strain Orsay) >gi|5457827|emb|CAB49317.1| (AJ248284) CELL DIVISION CONTROL PROTEIN 48, AAA FAMILY (CDC48-1) [Pyrococcus abyssi] Length = 795 Score = 169 bits (424), Expect = 4e-41 Identities = 111/294 (37%), Positives = 168/294 (56%), Gaps = 22/294 (7%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFGPPGTGK 134 + LI+ + W+DIGGL + K+ + +A+ + K P I PP+GILL+GPPGTGK Sbjct: 505 EVLIEVPNVHWDDIGGLEDVKQELREAVEWPL-KYPEAFKAYGITPPKGILLYGPPGTGK 563 Query: 135 SLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTM 194 +LLA AVA A F +V+ ++LSK+ GES K I +F ARQ +P+VIFIDE+D++ Sbjct: 564 TLLAKAVATESQANFIAVRGPEILSKWVGESEKNIREIFRKARQAAPTVIFIDEIDAIAP 623 Query: 195 KR-VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVP 251 +R ++ R+I LL EMDG +E V+V+ ATN P LD A+L R I VP Sbjct: 624 RRGTDVNRVTDRIINQLLTEMDGIQENAG-VVVIAATNRPDILDPALLRPGRFDRLILVP 682 Query: 252 LPDVNSAVEIFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATM-KMLEEMN 308 PD + EIFK+H RG+ DV L LA+ Y+G +IA V + A M M + Sbjct: 683 APDEKARFEIFKVHTRGMPLADDVDLKELARRT--EGYTGADIAAVCREAAMIAMRRALE 740 Query: 309 PELSDP-LRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 + P ++ S ++ +T+ DF+ A+ +I ++K ++ Y + ++F Sbjct: 741 KGIIKPGMKASEIR----RLAKVTMKDFEEALRKIGPSVSKETMEYYRKIQEQF 790 Score = 147 bits (367), Expect = 2e-34 Identities = 92/239 (38%), Positives = 140/239 (58%), Gaps = 15/239 (6%) Query: 81 LKALIKRST--ITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGT 132 +K + KR T +T+ DIGGL++ + I + I L + K IEPP+G+LL+GPPGT Sbjct: 168 VKEVEKRMTTGVTYEDIGGLKDVIEKIREMIELPLKHPELFEKLGIEPPKGVLLYGPPGT 227 Query: 133 GKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSL 192 GK+LLA AVAN NA F ++ +++SKY+GES + + +F A + +P++IFIDE+D++ Sbjct: 228 GKTLLAKAVANEANAYFIAINGPEIMSKYYGESEERLREVFKEAEENAPAIIFIDEIDAI 287 Query: 193 TMKRVSL-DDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIY 249 KR + + +R++ LLA MDG K R KVIV+ ATN P +D A+ R I Sbjct: 288 APKRSEVTGEVEKRVVAQLLALMDGLKSR-GKVIVIGATNRPDAIDPALRRPGRFDREIE 346 Query: 250 VPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMN 308 V +PD EI +IH RG+ + + + +K L + K+ K +EE+N Sbjct: 347 VGVPDRQGRKEILQIHTRGMPIEPDFRK--DDVLKILEDFKREGKFTKIID-KAIEEVN 402 >gb|AAC26698.1| (AC004077) putative katanin [Arabidopsis thaliana] Length = 393 Score = 169 bits (424), Expect = 4e-41 Identities = 102/234 (43%), Positives = 138/234 (58%), Gaps = 11/234 (4%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 I W I GL AKKL+ +A+ + I K P + P +GILLFGPPGTGK++LA AVA Sbjct: 109 IKWESIKGLENAKKLLKEAVVMPI-KYPTYFNGLLTPWKGILLFGPPGTGKTMLAKAVAT 167 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR----VSL 199 N TFF++ AS ++SK+ G+S KLI LF LAR +PS IF+DE+D++ +R S Sbjct: 168 ECNTTFFNISASSVVSKWRGDSEKLIRVLFDLARHHAPSTIFLDEIDAIISQRGGEGRSE 227 Query: 200 DDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAV 259 +A+RR+ LL +MDG ++ + V VL ATN PW+LD AML RL RI VPLPD + Sbjct: 228 HEASRRLKTELLIQMDGLQKTNELVFVLAATNLPWELDAAMLRRLEKRILVPLPDPEARR 287 Query: 260 EIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSD 313 +F++ + D PL YSG +I + K A M+ L L D Sbjct: 288 GMFEMLIPSQPGDEPLPHDVLVEKSEGYSGSDIRILCKEAAMQPLRRTLAILED 341 >gb|AAD47570.1|AF134119_1 (AF134119) SKD1 [Mus musculus] Length = 444 Score = 169 bits (423), Expect = 5e-41 Identities = 112/311 (36%), Positives = 166/311 (53%), Gaps = 29/311 (9%) Query: 11 KCQEEFERALSLGHYDKARLIALRCAELLRKIASENLSLSHILLEEAKKWEEKAKNVRKR 70 KC E +RA L Y K + E + E++ +EK + Sbjct: 61 KCTEYLDRAEKLKEYLKKK---------------EKKPQKPVKEEQSGPVDEKGNDSDGE 105 Query: 71 REGKNEYFDKLK------ALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPI-----E 119 E + KL+ +I+R + W+D+ GL AK+ + +A+ L I + Sbjct: 106 AESDDPEKKKLQNQLQGAIVIERPNVKWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRT 165 Query: 120 PPQGILLFGPPGTGKSLLASAVANSLN-ATFFSVKASDLLSKYFGESSKLISALFSLARQ 178 P +GILLFGPPGTGKS LA AVA N +TFFS+ +SDL+SK+ GES KL+ LF LAR+ Sbjct: 166 PWRGILLFGPPGTGKSYLAKAVATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARE 225 Query: 179 LSPSVIFIDEVDSLTMKRVSLD-DAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLD 237 PS+IFIDE+DSL R + +AARR+ L +M G D ++VL ATN PW LD Sbjct: 226 NKPSIIFIDEIDSLCGSRSENESEAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLD 285 Query: 238 EAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKR-LYSGREIANVV 296 A+ R RIY+PLP+ ++ +F++HL + + + K YSG +I+ +V Sbjct: 286 SAIRRRFEKRIYIPLPEAHARAAMFRLHLGSTQNSLTEADFQELGRKTDGYSGADISIIV 345 Query: 297 KLATMKMLEEM 307 + A M+ + ++ Sbjct: 346 RDALMQPVRKV 356 >gi|11425184 suppressor of K+ transport defect 1 [Homo sapiens] >gi|9885650|gb|AAG01471.1|AF282904_1 (AF282904) vacuolar protein sorting factor 4B [Homo sapiens] >gi|11225485|gb|AAG33022.1|AF195514_1 (AF195514) VPS4-2 ATPase [Homo sapiens] Length = 444 Score = 168 bits (421), Expect = 9e-41 Identities = 122/388 (31%), Positives = 194/388 (49%), Gaps = 60/388 (15%) Query: 34 RCAELLRKIASENLSLSHILLEEAKKWEEKAKNVRKRR--------------EGKNEYFD 79 + + +R +E L + L E K E+KA+ K EG+++ + Sbjct: 53 KAKQSIRAKCTEYLDRAEKLKEYLKNKEKKAQKPVKEGQPSPADEKGNDSDGEGESDDPE 112 Query: 80 KLKA--------LIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPI-----EPPQGILL 126 K K +I+R + W+D+ GL AK+ + +A+ L I + P +GILL Sbjct: 113 KKKLQNQLQGAIVIERPNVKWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILL 172 Query: 127 FGPPGTGKSLLASAVANSLN-ATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIF 185 FGPPGTGKS LA AVA N +TFFS+ +SDL+SK+ GES KL+ LF LAR+ PS+IF Sbjct: 173 FGPPGTGKSYLAKAVATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSIIF 232 Query: 186 IDEVDSLTMKRVSLD-DAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAMLSRL 244 IDE+DSL R + +AARR+ L +M G D ++VL ATN PW LD A+ R Sbjct: 233 IDEIDSLCGSRSENESEAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRRRF 292 Query: 245 PIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKR-LYSGREIANVVKLATMKM 303 RIY+PLP+ ++ +FK+HL + + + K YSG +I+ +V+ A M+ Sbjct: 293 EKRIYIPLPEPHARAAMFKLHLGTTQNSLTEADFRELGRKTDGYSGADISIIVRDALMQP 352 Query: 304 LEEM----------NPELSDP--------------------LRVSTLKGRDLTTRPLTLD 333 + ++ P +DP + + G L +++ Sbjct: 353 VRKVQSATHFKKVRGPSRADPNHLVDDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVSMS 412 Query: 334 DFKYAMARIKSPITKSDVKKYERWAKEF 361 D +++ K + + D+ K +++ ++F Sbjct: 413 DMLRSLSNTKPTVNEHDLLKLKKFTEDF 440 >pir||B71196 probable transitional endoplasmic reticulum ATPase - Pyrococcus horikoshii >gi|3258278|dbj|BAA30961.1| (AP000007) 798aa long hypothetical transitional endoplasmic reticulum ATPase [Pyrococcus horikoshii] Length = 798 Score = 168 bits (421), Expect = 9e-41 Identities = 110/294 (37%), Positives = 168/294 (56%), Gaps = 22/294 (7%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFGPPGTGK 134 + LI+ + W+DIGGL E K+ + +A+ + K P I PP+G+LL+GPPGTGK Sbjct: 508 EVLIEVPNVHWDDIGGLEEVKQELREAVEWPL-KYPEAFRAYGITPPKGVLLYGPPGTGK 566 Query: 135 SLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTM 194 +LLA AVA A F +V+ ++LSK+ GES K I +F ARQ +P+VIFIDE+D++ Sbjct: 567 TLLAKAVATESEANFIAVRGPEVLSKWVGESEKNIREIFRKARQAAPTVIFIDEIDAIAP 626 Query: 195 KR-VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVP 251 +R ++ R+I LL EMDG +E V+V+ ATN P LD A+L R I VP Sbjct: 627 RRGTDVNRVTDRLINQLLTEMDGIQENTG-VVVIAATNRPDILDPALLRPGRFDRLILVP 685 Query: 252 LPDVNSAVEIFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATM-KMLEEMN 308 PD + EIFK+H R + DV L LA+ Y+G +IA V + A M M + + Sbjct: 686 APDEEARFEIFKVHTRSMPLADDVDLRELARRT--EGYTGADIAAVCREAAMIAMRKALE 743 Query: 309 PELSDP-LRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 + P ++ +K + +T+ DF+ A+ +I ++K ++ Y + ++F Sbjct: 744 KGIIKPGMKADEIKQK----AKVTMKDFEEALKKIGPSVSKETMEYYRKIQEQF 793 Score = 155 bits (387), Expect = 9e-37 Identities = 102/259 (39%), Positives = 150/259 (57%), Gaps = 24/259 (9%) Query: 81 LKALIKRST--ITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGT 132 +K + KR T +T+ DIGGL++ + I + I L + K IEPP+G+LL+GPPGT Sbjct: 171 VKEVEKRMTTGVTYEDIGGLKDVIEKIREMIELPLKHPELFEKLGIEPPKGVLLYGPPGT 230 Query: 133 GKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSL 192 GK+LLA AVAN NA F ++ +++SKY+GES + + +F A + +PS+IFIDE+D++ Sbjct: 231 GKTLLAKAVANEANAYFIAINGPEIMSKYYGESEERLREVFKEAEENAPSIIFIDEIDAI 290 Query: 193 TMKRVSL-DDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIY 249 KR + + +R++ LLA MDG K R KVIV+ ATN P LD A+ R I Sbjct: 291 APKRSEVTGEVEKRVVAQLLALMDGLKGR-GKVIVIGATNRPDALDPALRRPGRFDREIE 349 Query: 250 VPLPDVNSAVEIFKIHLRGIHYDVP---------LSRLAKEAVKRLYSGREIANVVKLA- 299 V +PD EI +IH RG+ + L L KE R + I V+K++ Sbjct: 350 VGVPDKQGRKEILQIHTRGMPIEPDFRKEDVLKILEGLKKEGKFRDVIDKAIDRVMKVSE 409 Query: 300 --TMKMLEEMNPELSDPLR 316 K+L+E+N EL + +R Sbjct: 410 DDIPKVLKELNGELYEEVR 428 >emb|CAC14616.1| (AL449144) probable AAA ATPase [Leishmania major] >gi|11071813|emb|CAC14315.2| (AL359776) probable katanin-like protein [Leishmania major] Length = 565 Score = 168 bits (421), Expect = 9e-41 Identities = 108/285 (37%), Positives = 159/285 (54%), Gaps = 14/285 (4%) Query: 89 TITWNDIGGLREAKKLIAQAIGLSIA-----KSPIEPPQGILLFGPPGTGKSLLASAVAN 143 ++ W DI L AK L+ +A+ + + + + P +GILLFGPPGTGK+LLA AVA Sbjct: 275 SVRWRDIADLENAKHLLREAVVMPVKYPGLFQGILRPWKGILLFGPPGTGKTLLAKAVAT 334 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVS--LDD 201 TFF++ AS ++SK+ G+S KL+ LF LA +PS IFIDE+DSL R S + Sbjct: 335 ECRTTFFNIAASSVVSKWRGDSEKLVRMLFDLAVHYAPSTIFIDEIDSLMSARSSDGEHE 394 Query: 202 AARRMIGTLLAEMDGFKERK--DKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAV 259 +RRM LL +MDG +R+ + V VL A+N PWDLD AML RL RI V LP ++ V Sbjct: 395 GSRRMKTELLTQMDGLSKRRGGEVVFVLAASNVPWDLDTAMLRRLEKRILVSLPTRDARV 454 Query: 260 EIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATM----KMLEEMNPELSDPL 315 +F+ L + A A+ SG +I V + A M K++ ++ +D Sbjct: 455 LMFR-RLLPNSFASDADYEACAALTEGMSGADIDVVCREAMMRPVRKLISQLEAAGNDRN 513 Query: 316 RVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKE 360 + L L TL+D + ++A +S + +D+ KY+ W +E Sbjct: 514 AHARLPSEPLRPPAATLEDVQASVACTRSSVRVADLDKYDVWTRE 558 >gb|AAF51127.1| (AE003580) CG3326 gene product [Drosophila melanogaster] Length = 477 Score = 168 bits (420), Expect = 1e-40 Identities = 93/280 (33%), Positives = 160/280 (56%), Gaps = 15/280 (5%) Query: 92 WNDIGGLREAKKLIAQAIGLSIAKSPIE-----PPQGILLFGPPGTGKSLLASAVANSLN 146 W DI GL AK +AI + + + + PP+G+LLFGPPGTGK+L+A ++A+ Sbjct: 203 WEDIAGLESAKSTFLEAIIMPLRRPDLFTGVRCPPRGVLLFGPPGTGKTLIAKSIASQAK 262 Query: 147 ATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR-VSLDDAARR 205 A FFS+ S L SK+ G++ KL+ LF++A P++IFIDEVDSL KR + +++ R Sbjct: 263 AKFFSINPSSLTSKWVGDAEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKRSANENESTLR 322 Query: 206 MIGTLLAEMDGFKERKD-KVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKI 264 + L +DG ++ +V+V+ ATN P +LDEA+ R R+YVPLP + +I + Sbjct: 323 LKNEFLIHLDGAASNEEIRVLVIGATNRPQELDEAVRRRFVRRLYVPLPTREARQKIIEK 382 Query: 265 HLRGIHYDVPLSRLAKEA-VKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVSTLKGR 323 + + +++ + ++ + A + YSG ++ + + A+M L + P+ + + L Sbjct: 383 LIHQVKHNLDVRQVIELAELTDGYSGADVDTLCRYASMAPLRSLTPDQMEVIETHQLPA- 441 Query: 324 DLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEFAI 363 +T+DDFK A+ I ++ D K++E W + + + Sbjct: 442 ------VTMDDFKQALRVISKSVSSEDCKQFEAWNEIYGV 475 >gi|4759108 suppressor of K+ transport defect 1; mouse SKD1 homolog [Homo sapiens] >gi|9087199|sp|O75351|SKD1_HUMAN SKD1 PROTEIN >gi|3329390|gb|AAC39874.1| (AF038960) SKD1 homolog [Homo sapiens] Length = 444 Score = 167 bits (418), Expect = 2e-40 Identities = 122/388 (31%), Positives = 192/388 (49%), Gaps = 60/388 (15%) Query: 34 RCAELLRKIASENLSLSHILLEEAKKWEEKAKNVRKRR--------------EGKNEYFD 79 + + +R +E L + L E K E+KA+ K EG+++ + Sbjct: 53 KAKQSIRAKCTEYLDRAEKLKEYLKNKEKKAQKPVKEGQPSPADEKGNDSDGEGESDDPE 112 Query: 80 KLKA--------LIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPI-----EPPQGILL 126 K K +I R + W+D+ GL AK+ + +A+ L I + P +GILL Sbjct: 113 KRKLQNQLQGAIVIDRPNVKWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILL 172 Query: 127 FGPPGTGKSLLASAVANSLN-ATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIF 185 FGPPGTGKS LA AVA N +TFFS+ +SDL+SK+ GES KL+ LF LAR+ PS+IF Sbjct: 173 FGPPGTGKSYLAKAVATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSIIF 232 Query: 186 IDEVDSLTMKRVSLD-DAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAMLSRL 244 IDE+DSL R + +AARR+ L +M G D ++VL ATN PW LD A+ R Sbjct: 233 IDEIDSLCGSRSENESEAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRRRF 292 Query: 245 PIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKR-LYSGREIANVVKLATMKM 303 RIY+PLP+ ++ +FK+HL + + + K YSG +I +V+ A M+ Sbjct: 293 EKRIYIPLPEPHARAAMFKLHLGTTQNSLTEADFRELGRKTDGYSGADIGIIVRDALMQP 352 Query: 304 LEEM----------NPELSDP--------------------LRVSTLKGRDLTTRPLTLD 333 + ++ P +DP + + G L +++ Sbjct: 353 VRKVQSATHFKKVRGPSRADPNHLVDDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVSMS 412 Query: 334 DFKYAMARIKSPITKSDVKKYERWAKEF 361 D +++ K + + D+ K +++ ++F Sbjct: 413 DMLRSLSNTKPTVNEHDLLKLKKFTEDF 440 >gi|6677981 suppressor of K+ transport defect 1 [Mus musculus] >gi|1173444|sp|P46467|SKD1_MOUSE SKD1 PROTEIN >gi|1083520|pir||S48696 suppressor protein SKD1 - mouse >gi|557876|gb|AAA50497.1| (U10119) SKD1 [Mus musculus] Length = 444 Score = 167 bits (418), Expect = 2e-40 Identities = 97/232 (41%), Positives = 142/232 (60%), Gaps = 8/232 (3%) Query: 84 LIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPI-----EPPQGILLFGPPGTGKSLLA 138 +I+R + W+D+ GL AK+ + +A+ L I + P +GILLFGPPGTGKS LA Sbjct: 125 VIERPNVKWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLA 184 Query: 139 SAVANSLN-ATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRV 197 AVA N +TFFS+ +SDL+SK+ GES KL+ LF LAR+ PS+IFIDE+DSL R Sbjct: 185 KAVATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSIIFIDEIDSLCGSRS 244 Query: 198 SLD-DAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVN 256 + +AARR+ L +M G D ++VL ATN PW LD A+ R RIY+PLP+ + Sbjct: 245 ENESEAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEAH 304 Query: 257 SAVEIFKIHLRGIHYDVPLSRLAKEAVKR-LYSGREIANVVKLATMKMLEEM 307 + +F++HL + + + K YSG +I+ +V+ A M+ + ++ Sbjct: 305 ARAAMFRLHLGSTQNSLTEADFQELGRKTDGYSGVDISIIVRDALMQPVRKV 356 >pir||T03922 hypothetical protein F32D1.1 - Caenorhabditis elegans >gi|2291232|gb|AAB65351.1| (AF016427) Contains similarity to Pfam domain: PF00004 (AAA), Score=268.1, E-value=3.7e-77, N=1 [Caenorhabditis elegans] Length = 594 Score = 166 bits (415), Expect = 5e-40 Identities = 102/282 (36%), Positives = 156/282 (55%), Gaps = 20/282 (7%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSPI-----EPPQGILLFGPPGTGKSLLASAVANS 144 I W D+ GL AKK + + + L + + PP+G+LLFGPPGTGK+++ VA+ Sbjct: 313 IGWADVAGLEGAKKALREIVVLPFKRPDVFTGIRAPPKGVLLFGPPGTGKTMIGRCVASQ 372 Query: 145 LNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR-VSLDDAA 203 ATFF++ AS L SK+ GE KL+ ALFS+AR PSVIFIDE+DSL R S +++ Sbjct: 373 CKATFFNISASSLTSKWVGEGEKLVRALFSVARLKLPSVIFIDEIDSLLSSRSESEHESS 432 Query: 204 RRMIGTLLAEMDGFKERKD-KVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIF 262 RR+ L ++DG D +++VL ATN P +LDEA R R+Y+ LP+ S +I Sbjct: 433 RRIKTEFLVQLDGVNTAPDERLLVLGATNRPQELDEAARRRFQKRLYIALPEPESRTQIV 492 Query: 263 KIHLRGIHYDVPLSRLAKEAVKRL---YSGREIANVVKLATMKMLEEMNPELSDPLRVST 319 + L G +D+ L E ++ L YSG ++ + A M + ++ + + T Sbjct: 493 QNLLVGTRHDITNHNL--ERIRELTDGYSGADMRQLCTEAAMGPIRDIGDD------IET 544 Query: 320 LKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 + D+ R +T+ DF A ++ + S + Y W K+F Sbjct: 545 IDKDDI--RAVTVMDFAEAARVVRPTVDDSQLDAYAAWDKKF 584 >emb|CAB95999.1| (AL360054) AAA family ATPase with similarity to katanin; putative microtubule severing protein by similarity [Schizosaccharomyces pombe] Length = 741 Score = 166 bits (415), Expect = 5e-40 Identities = 108/299 (36%), Positives = 160/299 (53%), Gaps = 33/299 (11%) Query: 84 LIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPI-----EPPQGILLFGPPGTGKSLLA 138 ++ + W+DI GL AK + +A+ + + EP +G+LLFGPPGTGK++LA Sbjct: 450 VVSGDEVHWDDISGLEFAKHSLKEAVVYPFLRPDLFQGLREPARGMLLFGPPGTGKTMLA 509 Query: 139 SAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVS 198 AVA + FFS+ AS L SK+ GES KL+ ALF+LA++LSPS+IF+DE+DSL R S Sbjct: 510 RAVATESRSVFFSISASSLTSKFLGESEKLVRALFTLAKKLSPSIIFVDEIDSLLSARSS 569 Query: 199 --LDDAARRMIGT-------LLAEMDGFKERKD--KVIVLTATNAPWDLDEAMLSRLPIR 247 + R I T LA ++ D +V+VL ATN PW +D+A R R Sbjct: 570 DGNEHETSRRIKTEFLIQWSSLARAAASRQTADHPRVLVLAATNLPWCIDDAARRRFVRR 629 Query: 248 IYVPLPDVNSAVEIFKIHLRGI--HYDVPLSRLAKEAVKR---LYSGREIANVVKLATMK 302 Y+PLPD + ++HL + + LS EA+ + YSG ++ + K A M Sbjct: 630 TYIPLPDETTR----RLHLNNLLKYQKHSLSLEDIEAIVKATEYYSGSDLTALAKDAAMG 685 Query: 303 MLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 L + L L + + RP+ LDDFK ++ I+ + +++Y W KEF Sbjct: 686 PLRSLGESL--------LFTKMESIRPINLDDFKTSIKVIRPSVNLQGLERYSEWDKEF 736 >pir||H71114 probable cell division control protein (transitional endoplasmic reticulum ATPase) - Pyrococcus horikoshii >gi|3257095|dbj|BAA29778.1| (AP000003) 840aa long hypothetical cell division control protein (transitional endoplasmic reticulum ATPase) [Pyrococcus horikoshii] Length = 840 Score = 164 bits (412), Expect = 1e-39 Identities = 121/352 (34%), Positives = 183/352 (51%), Gaps = 38/352 (10%) Query: 27 KARLIALRCAELLRKIASENLSLSHILLEEAKKWEEKAKNVRKRREGKNEYFDKLK---- 82 +A ++ LR KI E S+ +LEE K V KR ++++ LK Sbjct: 485 EAAMVVLRRLINEGKINPEAESIPREVLEELK--------VTKR-----DFYEALKMVEP 531 Query: 83 -----ALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPG 131 LI+ + W+DIGGL E K+ + +A+ + K I PP+G+LL+GPPG Sbjct: 532 SALREVLIEVPNVHWDDIGGLEEVKQELREAVEWPLKYPKAFKKLGITPPKGVLLYGPPG 591 Query: 132 TGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDS 191 TGK+LLA AVA A F +V+ ++LSK+ GES K I +F ARQ +P++IFIDE+D+ Sbjct: 592 TGKTLLAKAVATESEANFIAVRGPEVLSKWVGESEKRIREIFRKARQAAPAIIFIDEIDA 651 Query: 192 LTMKRVSL--DDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIR 247 + R + + R+I LL EMDG E V+V+ ATN P LD A+L R Sbjct: 652 IAPARGTSEGEKVTDRIINQLLTEMDGLVENSG-VVVIAATNRPDILDPALLRPGRFDRL 710 Query: 248 IYVPLPDVNSAVEIFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLE 305 I VP PD + EIFK+H R + DV L LA+ Y+G +IA V + A + L Sbjct: 711 ILVPAPDEEARFEIFKVHTRSMPLADDVDLRELARRT--EGYTGADIAAVCREAALNALR 768 Query: 306 EMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERW 357 + + ++ L +T DF+ A+ ++K ++K ++ Y ++ Sbjct: 769 RVVKSVPKE-KLEEESEEFLNKLVVTRKDFEEALKKVKPSVSKYMMEYYRQF 819 Score = 146 bits (364), Expect = 5e-34 Identities = 83/190 (43%), Positives = 120/190 (62%), Gaps = 12/190 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFGPPGTGKSLLASAVA 142 +T+ DIGGL+EA + I + + L + K P IEPP+G+LL+GPPGTGK+LLA AVA Sbjct: 209 VTYEDIGGLKEAIQKIREMVELPL-KHPELFERLGIEPPKGVLLYGPPGTGKTLLAKAVA 267 Query: 143 NSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVS-LDD 201 N NA F ++ +++SKY+GES + + +F A + +P++IFIDE+D++ KR + + Sbjct: 268 NEANAYFIAINGPEIMSKYYGESEERLREIFKEAEENAPAIIFIDEIDAIAPKREEVVGE 327 Query: 202 AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAV 259 +R++ LL MDG K R KVIV+ ATN P LD A+ R I V +PD Sbjct: 328 VEKRVVSQLLTLMDGLKGR-GKVIVIGATNRPDALDPALRRPGRFDREIEVGVPDKQGRK 386 Query: 260 EIFKIHLRGI 269 EI +IH RG+ Sbjct: 387 EILQIHTRGM 396 >sp|Q58556|YB56_METJA CELL DIVISION CYCLE PROTEIN 48 HOMOLOG MJ1156 >gi|2118117|pir||C64444 cell division control protein CDC48 homolog - Methanococcus jannaschii >gi|1591785|gb|AAB99153.1| (U67557) cell division control protein 48 (cdc48), AAA family [Methanococcus jannaschii] Length = 903 Score = 164 bits (411), Expect = 1e-39 Identities = 99/237 (41%), Positives = 142/237 (59%), Gaps = 15/237 (6%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKS 135 + L++ + W DIGGL E K+ + +A+ + K + PP+G+LLFGPPGTGK+ Sbjct: 441 EVLVEVPNVKWEDIGGLEEVKQELREAVEWPLKAKEVFEKIGVRPPKGVLLFGPPGTGKT 500 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 LLA AVAN A F SVK ++ SK+ GES K I +F ARQ +P +IF DE+D++ K Sbjct: 501 LLAKAVANESGANFISVKGPEIFSKWVGESEKAIREIFRKARQSAPCIIFFDEIDAIAPK 560 Query: 196 R-VSLDDAAR-RMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVP 251 R L A +++ LL E+DG +E KD V+V+ ATN P +D A+L RL I VP Sbjct: 561 RGRDLSSAVTDKVVNQLLTELDGMEEPKD-VVVIAATNRPDIIDPALLRPGRLDRVILVP 619 Query: 252 LPDVNSAVEIFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEE 306 +PD + ++IFKIH R ++ DV L LAK+ Y+G +I + + A M + E Sbjct: 620 VPDEKARLDIFKIHTRSMNLAEDVNLEELAKKT--EGYTGADIEALCREAAMLAVRE 674 Score = 155 bits (389), Expect = 5e-37 Identities = 104/283 (36%), Positives = 155/283 (54%), Gaps = 17/283 (6%) Query: 72 EGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGIL 125 E K E ++K K +T+ DIGGL+E K + + I L + K IEPP+G+L Sbjct: 159 ELKEEPVSEIKET-KVPDVTYEDIGGLKEEVKKVREMIELPMRHPELFEKLGIEPPKGVL 217 Query: 126 LFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIF 185 L GPPGTGK+LLA AVAN A F+ + +++SKY GE+ + + +F A + +PS+IF Sbjct: 218 LVGPPGTGKTLLAKAVANEAGANFYVINGPEIMSKYVGETEENLRKIFEEAEENAPSIIF 277 Query: 186 IDEVDSLTMKR-VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--S 242 IDE+D++ KR + + RR++ LL MDG K R +V+V+ ATN P LD A+ Sbjct: 278 IDEIDAIAPKRDEATGEVERRLVAQLLTLMDGLKGR-GQVVVIGATNRPNALDPALRRPG 336 Query: 243 RLPIRIYVPLPDVNSAVEIFKIHLRG--IHYDVPLSRLAKEAVKRLYSGREIANVVKLAT 300 R I + +PD EI +IH R + DV L LA V + G ++A + K A Sbjct: 337 RFDREIVIGVPDREGRKEILQIHTRNMPLAEDVDLDYLAD--VTHGFVGADLAALCKEAA 394 Query: 301 MKMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIK 343 M+ L + P + L + L +T+DDFK A+ ++ Sbjct: 395 MRALRRVLPSID--LEAEEIPKEVLDNLKVTMDDFKEALKDVE 435 >pir||B72479 probable transitional endoplasmic reticulum ATPase APE2474 - Aeropyrum pernix (strain K1) >gi|5106179|dbj|BAA81490.1| (AP000064) 699aa long hypothetical transitional endoplasmic reticulum ATPase [Aeropyrum pernix] Length = 699 Score = 163 bits (408), Expect = 3e-39 Identities = 99/281 (35%), Positives = 158/281 (55%), Gaps = 34/281 (12%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSI------AKSPIEPPQGILLFGPPGTGKSLLASAVAN 143 + W+DIGGL + K+ + + + + + I PP+G+LLFGPPGTGK+LLA AVA Sbjct: 420 VRWSDIGGLEDVKQELREVVEWPLKHPEAFTRMGIRPPRGVLLFGPPGTGKTLLAKAVAT 479 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDAA 203 A F +V+ ++LSK+ GES + I +F+ ARQ +P+V+F DE+D++ R D Sbjct: 480 ESGANFIAVRGPEILSKWVGESERAIREIFAKARQHAPAVVFFDEIDAIAPVR-GTDVGT 538 Query: 204 R---RMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSA 258 R R++ LL E+DG + D V+V+ ATN P +D A++ RL IYVP PD +S Sbjct: 539 RVTERIVSQLLTEIDGVSDLHD-VVVIAATNRPDMVDPALMRPGRLEKMIYVPPPDFSSR 597 Query: 259 VEIFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLR 316 +EI +IH R + DV L+ +A+ Y+G +I +V+ A++ L E Sbjct: 598 LEILRIHTRKVPLAEDVDLAEIARRT--EGYTGADIEALVREASLAALRE---------- 645 Query: 317 VSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERW 357 D+ +++ F+ A+ ++K +T V+ Y+RW Sbjct: 646 -------DINAAEVSMRHFEVALKKVKPSVTPQMVEYYKRW 679 Score = 161 bits (402), Expect = 2e-38 Identities = 99/264 (37%), Positives = 157/264 (58%), Gaps = 16/264 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKSLLASAVAN 143 +T+ DIGGL+E + + + + L + + IEPP+GILL+GPPGTGK+LLA AVAN Sbjct: 147 VTYEDIGGLKEVIEKVREMVELPLRHPEIFKRLGIEPPKGILLYGPPGTGKTLLAKAVAN 206 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVS-LDDA 202 +A F S+ +++SKY+GES + + +F A++ +PS+IFIDE+D++ KR + + Sbjct: 207 EADAYFISINGPEIMSKYYGESEQRLREIFEEAKKNAPSIIFIDEIDAIAPKRDEVVGEV 266 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVE 260 RR++ LLA MDG E + VIV+ ATN P +D A+ R I VPLPD + +E Sbjct: 267 ERRVVAQLLALMDGL-EARGNVIVIAATNRPNAIDPALRRPGRFDREIEVPLPDKHGRLE 325 Query: 261 IFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 I +IH R + D+ L +LA+ + + ++G ++A + + A M L PE+ L Sbjct: 326 ILQIHTRHMPLAEDMDLEKLAE--MTKGFTGADLAALAREAAMYALRRYLPEID--LDQE 381 Query: 319 TLKGRDLTTRPLTLDDFKYAMARI 342 ++ L +T++DF A+ I Sbjct: 382 SIPVEVLEKMVVTMEDFLKALREI 405 >gi|11499681 cell division control protein 48, AAA family (cdc48-2) [Archaeoglobus fulgidus] >gi|7435750|pir||B69512 cell division control protein 48, AAA family (cdc48-2) homolog - Archaeoglobus fulgidus >gi|2648442|gb|AAB89157.1| (AE000959) cell division control protein 48, AAA family (cdc48-2) [Archaeoglobus fulgidus] Length = 811 Score = 163 bits (408), Expect = 3e-39 Identities = 102/284 (35%), Positives = 156/284 (54%), Gaps = 34/284 (11%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKSLLASAVAN 143 +TWND+GGL + K+ I +A+ + K I+PP+G+LL+GPPGTGK+L+A AVAN Sbjct: 531 VTWNDVGGLEDVKREIIEAVEWPLKYPEKFKKFGIKPPKGVLLYGPPGTGKTLIAKAVAN 590 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDAA 203 A F S+K +LSK+ GES K + +F ARQ++P +IF DE+D++ R +D+ + Sbjct: 591 ESEANFISIKGGQILSKWLGESEKAVRKIFRKARQVAPCIIFFDEIDAIAQMR-GIDEGS 649 Query: 204 R---RMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSA 258 R R++ LL EMDG +E V+V+ ATN P LD A+L R +YV PD S Sbjct: 650 RAVERVLNQLLTEMDGLEELHG-VVVIGATNRPDILDPALLRPGRFDRMVYVRPPDKKSR 708 Query: 259 VEIFKIHLRG--IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLR 316 + IFKIH R + DV L LA + Y G +I + + A M + E Sbjct: 709 LAIFKIHTRDMPLSEDVDLEELAD--LTEGYVGADIEAICREAVMLAIRE---------- 756 Query: 317 VSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKE 360 ++ + + F A+ +IK + ++ + YER+ ++ Sbjct: 757 -------NINAEKVEMRHFLEALKKIKPSVNEAMLNFYERFEEK 793 Score = 146 bits (366), Expect = 3e-34 Identities = 86/240 (35%), Positives = 141/240 (57%), Gaps = 11/240 (4%) Query: 87 RSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKSLLASA 140 ++ IT+ DIGGL+E + + + I L + + IEPP+G+LL+GPPGTGK+L+A A Sbjct: 191 KAGITYEDIGGLKEELQKVREVIELPLRYPELFQRLGIEPPKGVLLYGPPGTGKTLIAKA 250 Query: 141 VANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL- 199 VAN + A+FF++ +++SK++GES + + +F A++ +PS+IFIDE+DS+ KR + Sbjct: 251 VANEIGASFFTINGPEIMSKFYGESEQRLREIFEEAKENAPSIIFIDEIDSIAPKREEVT 310 Query: 200 DDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNS 257 + RR++ LL MDG +ER +VIV+ ATN +D A+ R I + +PD Sbjct: 311 GEVERRVVAQLLTLMDGLEER-GQVIVIGATNRIDAVDPALRRPGRFDREIEIGVPDREG 369 Query: 258 AVEIFKIHLRGIHYDVPLSR-LAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLR 316 EIF+IH R + + SR +A++R + ++K E N E + ++ Sbjct: 370 RYEIFQIHTRNMPLEAKYSREFVLDAIERFKRQVDDPELIKNLDFLYDEIKNSETEEEVK 429 >dbj|BAB02560.1| (AP000417) contains similarity to unknown protein~gb|AAF02877.1~gene_id:MMB12.22 [Arabidopsis thaliana] Length = 270 Score = 162 bits (407), Expect = 4e-39 Identities = 95/251 (37%), Positives = 146/251 (57%), Gaps = 13/251 (5%) Query: 118 IEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLAR 177 + P +GILLFGPPGTGK+LLA A+A A F S+ S L SK+FG++ KL ALFS A Sbjct: 13 LRPCKGILLFGPPGTGKTLLAKALATEAGANFISITGSTLTSKWFGDAEKLTKALFSFAS 72 Query: 178 QLSPSVIFIDEVDSLTMKRVSL--DDAARRMIGTLLAEMDGFKER-KDKVIVLTATNAPW 234 +L+P +IF+DEVDSL R +A RRM +A DG + + ++++L ATN P+ Sbjct: 73 KLAPVIIFVDEVDSLLGARGGAFEHEATRRMRNEFMAAWDGLRSKDSQRILILGATNRPF 132 Query: 235 DLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHL--RGIHYDVPLSRLAKEAVKRLYSGREI 292 DLD+A++ RLP RIYV LPD + ++I KI L + +LAKE YSG ++ Sbjct: 133 DLDDAVIRRLPRRIYVDLPDAENRLKILKIFLTPENLETGFEFDKLAKET--EGYSGSDL 190 Query: 293 ANVVKLATMKMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPIT--KSD 350 N+ A + ++E+ E + ++ RPL+LDDF + A++ + + Sbjct: 191 KNLCIAAAYRPVQELLQEENK----DSVTNASPDLRPLSLDDFIQSKAKVSPSVAYDATT 246 Query: 351 VKKYERWAKEF 361 + + +W +++ Sbjct: 247 MNELRKWNEQY 257 >gb|AAK42565.1| AAA family ATPase [Sulfolobus solfataricus] Length = 607 Score = 162 bits (405), Expect = 7e-39 Identities = 104/294 (35%), Positives = 165/294 (55%), Gaps = 29/294 (9%) Query: 80 KLKALIKRSTITWNDIGGLREAKKLIAQAIGLSI------AKSPIEPPQGILLFGPPGTG 133 K K I+ ITW+DIGG +AKK I + I L + K ++PP+G+LLFGPPG G Sbjct: 48 KKKVEIEDKKITWDDIGGYEDAKKEIREYIELPLKNKDVATKYGLKPPKGMLLFGPPGCG 107 Query: 134 KSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLT 193 K+++ A+AN F V SD++SK++GES + LF+ AR+ +P ++F DE+D++ Sbjct: 108 KTMMMRALANESKLNFLYVNISDIMSKWYGESEARLRELFNNARKNAPCILFFDEIDTIG 167 Query: 194 MKRVSL--DDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIY 249 +KR S D R++ +L+E+DG +D VIV+ +TN P LD+A+L R IY Sbjct: 168 VKRESHTGDSVTPRLLSLMLSEIDGL-HSEDGVIVVGSTNVPQMLDKALLRAGRFDKLIY 226 Query: 250 VPLPDVNSAVEIFKIHLRG--IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEM 307 + P+ + +I +IH RG + DV +LA+ + YSG ++AN+ + A K+ E Sbjct: 227 IGPPNKEARKQILQIHCRGKPLAEDVDFDKLAE--ITERYSGADLANLCQEAARKVASE- 283 Query: 308 NPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 + KG D R +T+ DF + + K IT ++ YE++ +F Sbjct: 284 ----------AIEKGAD---RKITMADFIELIKKYKPSITLQMIEDYEKFRLDF 324 Score = 112 bits (278), Expect = 6e-24 Identities = 95/348 (27%), Positives = 174/348 (49%), Gaps = 39/348 (11%) Query: 12 CQEEFERALSLGHYDKARLIALRCAELLRKIASENLSLSHILLEEAKKWEEKAKNVRKRR 71 CQE + S +K + A+ + I S++ ++E+ +K+ + ++ Sbjct: 273 CQEAARKVASEA-IEKGADRKITMADFIELIKKYKPSITLQMIEDYEKFRLDFERRVRKG 331 Query: 72 EGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSI------AKSPIEPPQGIL 125 E +NE +KL T NDIGG E K + + + L + + + P +GIL Sbjct: 332 EEENELEEKL---------TLNDIGGYNEIKTELKELLELQLYHYKLLEQLRVPPIRGIL 382 Query: 126 LFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIF 185 L+GPPG GK+++A A+A +LN ++ ++++ K + + I +F+ AR+ P++I Sbjct: 383 LYGPPGVGKTMMAKALAKTLNVKLIALSGAEIMYKGYEGAIAAIKEVFNRARENKPAIIL 442 Query: 186 IDEVDSLTMKR--VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML-- 241 +DE+D++ KR S D++ +++ LL EMDG + K+ V+V+ TN +D A+L Sbjct: 443 LDELDAIASKRSYKSYGDSS-KIVNQLLTEMDGIRSLKE-VVVIGTTNRLKAIDPALLRP 500 Query: 242 SRLPIRIYVPLPDVNSAVEIFKIHLRGIHYD-VPLSRLAKEAVKRLYSGREIANVVKLAT 300 R I++PLP+ ++I ++ + V LA + YSG ++A + + A Sbjct: 501 GRFDKIIHMPLPNREERLDILMKYIGKEECEKVDCGILADQT--EGYSGADLAALAREAK 558 Query: 301 MKMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITK 348 MK+L+ S L+G + R LT +D A+ +I + K Sbjct: 559 MKVLK------------SILRGE--SNRTLTREDLIDALNKIHPSVKK 592 >gb|AAK41191.1| AAA family ATPase, p60 katanin [Sulfolobus solfataricus] Length = 372 Score = 161 bits (403), Expect = 1e-38 Identities = 103/323 (31%), Positives = 170/323 (51%), Gaps = 27/323 (8%) Query: 53 LLEEAKK---WEEKAKNVRKRREGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAI 109 ++ E KK + EK G N + + ++ +++ DI GL + K+ + +AI Sbjct: 60 MINEYKKRISYLEKVLPASSDGSGDNTSPPEEVVITEKPKVSFKDIVGLDDVKEALREAI 119 Query: 110 GLSIAKSPIEP---PQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESS 166 + + P P+GILL+GPPG GK+++A+AVAN +++ F + A+ ++SK+ GE+ Sbjct: 120 IYPTKRPDLFPLGWPRGILLYGPPGCGKTMIAAAVANEIDSIFMQLDAASVMSKWLGEAE 179 Query: 167 KLISALFSLARQLS-----PSVIFIDEVDSLTMKRVSLDDAARRMIGTLLAEMDGFKERK 221 K ++ +F +AR+ S P++IFIDE+D+L + R+ L EMDG ++ Sbjct: 180 KNVANVFKMAREESKKQNKPAIIFIDELDALLGVYSTEVGGEARVRNQFLKEMDGLLDKS 239 Query: 222 D--KVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLA 279 + KV V+ ATN PW LDEA L R RIYVPLPD + +FK + I D +S Sbjct: 240 ENYKVYVIGATNKPWRLDEAFLRRFQKRIYVPLPDYEQRLSLFKYYTSKIKLDTEVSLEE 299 Query: 280 KEAVKRLYSGREIANVVKLATMKMLEEM-NPELSDPLRVSTLKGRDLTTRPLTLDDFKYA 338 + Y+ +I ++V+ A +K+++EM L +P R +TL DFK Sbjct: 300 LAKLTEGYTASDIRDIVQAAHIKVVKEMFKNNLGEP-------------RTITLQDFKDI 346 Query: 339 MARIKSPITKSDVKKYERWAKEF 361 + + +K YE W ++F Sbjct: 347 LKVRMPSVNPELIKAYEAWTEKF 369 >pir||T01303 hypothetical protein T14P8.7 - Arabidopsis thaliana >gi|3193292|gb|AAC19276.1| (AF069298) similar to ATPases associated with various cellular activites (Pfam: AAA.hmm, score: 230.91) [Arabidopsis thaliana] >gi|7269007|emb|CAB80740.1| (AL161494) coded for by A. thaliana cDNA T88606, coded for by A. thaliana cDNA T75804~strong similarity to similar to ATPases associated with various cellular activites (Pfam: AAA.hmm, score: 230.91)~Contains ATP/GTP-binding site motif A (P-loop) AA111> Length = 371 Score = 161 bits (403), Expect = 1e-38 Identities = 110/340 (32%), Positives = 186/340 (54%), Gaps = 26/340 (7%) Query: 42 IASENLSLSHILLEEAKKWEEKAKNVRKRREGKNEYFDKLKA-LIKRSTI--TWNDIGGL 98 I++E++S L + + + K K +NE+ KL + +I S I +++DIG L Sbjct: 15 ISAESISYGLQTLHDIQNENKSLKKSLKDVVTENEFEKKLLSDVIPPSDIGVSFDDIGAL 74 Query: 99 REAKKLIAQAIGLSIAKSPI-------EPPQGILLFGPPGTGKSLLASAVANSLNATFFS 151 K+ + + + L + + + +P +GILLFGPPGTGK++LA AVA A F + Sbjct: 75 ENVKETLKELVMLPLQRPELFDKGQLTKPTKGILLFGPPGTGKTMLAKAVATEAGANFIN 134 Query: 152 VKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVS--LDDAARRMIGT 209 + S + SK+FGE K + A+FSLA +++PSVIF+DEVDS+ +R + +A R+M Sbjct: 135 ISMSSITSKWFGEGEKYVKAVFSLASKIAPSVIFVDEVDSMLGRRENPGEHEAMRKMKNE 194 Query: 210 LLAEMDGFKER-KDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHL-- 266 + DG + + +++V+VL ATN P+DLDEA++ RLP R+ V LPD + +I + L Sbjct: 195 FMVNWDGLRTKDRERVLVLAATNRPFDLDEAVIRRLPRRLMVNLPDATNRSKILSVILAK 254 Query: 267 RGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVSTLKGRD-- 324 I DV L +A + YSG ++ N+ A + E+ + + + R Sbjct: 255 EEIAPDVDLEAIAN--MTDGYSGSDLKNLCVTAAHFPIREILEKEKKEKTAAQAENRPTP 312 Query: 325 -----LTTRPLTLDDFKYAMARIKSPIT--KSDVKKYERW 357 R LT++DFK A ++ + ++ S++ + ++W Sbjct: 313 PLYSCTDVRSLTMNDFKAAHDQVCASVSSDSSNMNELQQW 352 >sp|P46464|CDCH_HALSA CDCH PROTEIN >gi|629399|pir||S47018 cdcH protein - Halobacterium salinarum >gi|517390|emb|CAA56097.1| (X79560) cdcH [Halobacterium salinarum] Length = 742 Score = 160 bits (400), Expect = 3e-38 Identities = 98/265 (36%), Positives = 152/265 (56%), Gaps = 17/265 (6%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSI------AKSPIEPPQGILLFGPPGTGKS 135 + L++ ITW+D+GGL EAK + +++ + + +EPP G+LL+GPPGTGK+ Sbjct: 451 EVLVELPKITWDDVGGLTEAKNNVKESVEWPLNQPEKFTRMGVEPPAGVLLYGPPGTGKT 510 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 L+A AVAN NA F SV+ LLSK+ GES K I F ARQ++P+VIF DE+DSL Sbjct: 511 LMAKAVANETNANFISVRGPQLLSKWVGESEKAIRQTFRKARQVAPTVIFFDELDSLAPG 570 Query: 196 R--VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVP 251 R ++ + R++ LL E+DG +E ++V+V+ ATN P +D A++ R + V Sbjct: 571 RGQTGGNNVSERVVNQLLTELDGLEE-MEEVMVIAATNRPDIIDPALIRSGRFDRLVQVG 629 Query: 252 LPDVNSAVEIFKIHLRG--IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNP 309 P + +I KIH + + DV L LA+ A Y G ++AN+ + A ++ L + Sbjct: 630 QPGIEGREQILKIHTQDTPLAADVSLRELAERADG--YVGSDLANIAREAAIEALRD--D 685 Query: 310 ELSDPLRVSTLKGRDLTTRPLTLDD 334 E +D + ++ + RP DD Sbjct: 686 EDADDVGMAHFRAAMENVRPTITDD 710 Score = 152 bits (380), Expect = 6e-36 Identities = 101/265 (38%), Positives = 150/265 (56%), Gaps = 16/265 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKSLLASAVAN 143 IT+ DIGGL + + + + L + K IEPPQG+LL GPPGTGK+LLA AVAN Sbjct: 186 ITYEDIGGLENEIQRVREMVELPMKHPQIFQKLGIEPPQGVLLHGPPGTGKTLLAKAVAN 245 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL-DDA 202 +A+FFS+ +++SKY+GES + + +F A+ SPS+IFIDE+DS+ KR + + Sbjct: 246 ETSASFFSIAGPEIISKYYGESEQQLREIFEDAKDDSPSIIFIDELDSIAPKREDVTGEV 305 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVE 260 RR++ LL MDG E + +VIV+ ATN +D A+ R I + +PD E Sbjct: 306 ERRVVAQLLTMMDGL-EGRGQVIVIAATNRVDAVDPALRRPGRFDREIEIGVPDEIGREE 364 Query: 261 IFKIHLRG--IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 I KIH RG + DV LS LA + + G +I ++ K A M+ L PE+ L Sbjct: 365 ILKIHTRGMPLSDDVNLSTLADDT--HGFVGADIESLSKEAAMRALRRYLPEID--LDEE 420 Query: 319 TLKGRDLTTRPLTLDDFKYAMARIK 343 + + + +DFK A++ ++ Sbjct: 421 DIPPSLIDRMIVKREDFKGALSEVE 445 >gb|AAG19919.1| (AE005075) cell division cycle protein; Cdc48c [Halobacterium sp. NRC-1] Length = 742 Score = 160 bits (400), Expect = 3e-38 Identities = 98/265 (36%), Positives = 152/265 (56%), Gaps = 17/265 (6%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSI------AKSPIEPPQGILLFGPPGTGKS 135 + L++ ITW+D+GGL EAK + +++ + + +EPP G+LL+GPPGTGK+ Sbjct: 451 EVLVELPKITWDDVGGLTEAKNNVKESVEWPLNQPEKFTRMGVEPPAGVLLYGPPGTGKT 510 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 L+A AVAN NA F SV+ LLSK+ GES K I F ARQ++P+VIF DE+DSL Sbjct: 511 LMAKAVANETNANFISVRGPQLLSKWVGESEKAIRQTFRKARQVAPTVIFFDELDSLAPG 570 Query: 196 R--VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVP 251 R ++ + R++ LL E+DG +E ++V+V+ ATN P +D A++ R + V Sbjct: 571 RGQTGGNNVSERVVNQLLTELDGLEE-MEEVMVIAATNRPDIIDPALIRSGRFDRLVQVG 629 Query: 252 LPDVNSAVEIFKIHLRG--IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNP 309 P + +I KIH + + DV L LA+ A Y G ++AN+ + A ++ L + Sbjct: 630 QPGIEGREQILKIHTQDTPLAADVSLRELAERADG--YVGSDLANIAREAAIEALRD--D 685 Query: 310 ELSDPLRVSTLKGRDLTTRPLTLDD 334 E +D + ++ + RP DD Sbjct: 686 EDADDVGMAHFRAAMENVRPTITDD 710 Score = 152 bits (380), Expect = 6e-36 Identities = 101/265 (38%), Positives = 150/265 (56%), Gaps = 16/265 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKSLLASAVAN 143 IT+ DIGGL + + + + L + K IEPPQG+LL GPPGTGK+LLA AVAN Sbjct: 186 ITYEDIGGLENEIQRVREMVELPMKHPQIFQKLGIEPPQGVLLHGPPGTGKTLLAKAVAN 245 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL-DDA 202 +A+FFS+ +++SKY+GES + + +F A+ SPS+IFIDE+DS+ KR + + Sbjct: 246 ETSASFFSIAGPEIISKYYGESEQQLREIFEDAKDDSPSIIFIDELDSIAPKREDVTGEV 305 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVE 260 RR++ LL MDG E + +VIV+ ATN +D A+ R I + +PD E Sbjct: 306 ERRVVAQLLTMMDGL-EGRGQVIVIAATNRVDAVDPALRRPGRFDREIEIGVPDEIGREE 364 Query: 261 IFKIHLRG--IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 I KIH RG + DV LS LA + + G +I ++ K A M+ L PE+ L Sbjct: 365 ILKIHTRGMPLSDDVNLSTLADDT--HGFVGADIESLSKEAAMRALRRYLPEID--LDEE 420 Query: 319 TLKGRDLTTRPLTLDDFKYAMARIK 343 + + + +DFK A++ ++ Sbjct: 421 DIPPSLIDRMIVKREDFKGALSEVE 445 >gb|AAF02877.1|AC009525_11 (AC009525) Unknown protein [Arabidopsis thaliana] Length = 1217 Score = 159 bits (399), Expect = 4e-38 Identities = 111/334 (33%), Positives = 183/334 (54%), Gaps = 26/334 (7%) Query: 48 SLSHILLEEAKKWEEKAKNVRKRREGKNEYFDKLKA-LIKRSTI--TWNDIGGLREAKKL 104 S S+ LL + ++ RK +NE+ KL + +I S I +++DIG L K Sbjct: 867 SPSYELLRTYSQGQQAYHLGRKDVVTENEFEKKLLSDVIPPSDIGVSFSDIGALENVKDT 926 Query: 105 IAQAIGLSIAKSPI-------EPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDL 157 + + + L + + + +P +GILLFGPPGTGK++LA AVA A F ++ S + Sbjct: 927 LKELVMLPLQRPELFGKGQLTKPTKGILLFGPPGTGKTMLAKAVATEAGANFINISMSSI 986 Query: 158 LSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVS--LDDAARRMIGTLLAEMD 215 SK+FGE K + A+FSLA +++PSVIF+DEVDS+ +R + +A R+M + D Sbjct: 987 TSKWFGEGEKYVKAVFSLASKIAPSVIFVDEVDSMLGRRENPGEHEAMRKMKNEFMINWD 1046 Query: 216 GFKER-KDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHL--RGIHYD 272 G + + K++V+VL ATN P+DLDEA++ RLP R+ V LPD + +I + L + D Sbjct: 1047 GLRTKDKERVLVLAATNRPFDLDEAVIRRLPRRLMVNLPDSANRSKILSVILAKEEMAED 1106 Query: 273 VPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVSTLKGRDL------- 325 V L +A + YSG ++ N+ A + E+ + V+ + R + Sbjct: 1107 VDLEAIAN--MTDGYSGSDLKNLCVTAAHLPIREILEKEKKERSVAQAENRAMPQLYSST 1164 Query: 326 TTRPLTLDDFKYAMARIKSPIT--KSDVKKYERW 357 RPL ++DFK A ++ + + S++ + ++W Sbjct: 1165 DVRPLNMNDFKTAHDQVCASVASDSSNMNELQQW 1198 >pir||T40781 26S proteinase subunit - fission yeast (Schizosaccharomyces pombe) >gi|2894288|emb|CAA17029.1| (AL021837) 26s protease subunit [Schizosaccharomyces pombe] Length = 660 Score = 158 bits (395), Expect = 1e-37 Identities = 105/308 (34%), Positives = 164/308 (53%), Gaps = 35/308 (11%) Query: 76 EYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPI-----EPPQGILLFGPP 130 EY + + + W+DI GL +AK + +A+ + + EP QG+LLFGPP Sbjct: 362 EYAIMNEIISNHEPVYWSDIAGLDDAKNSLKEAVIYPFLRPELFQGLREPVQGMLLFGPP 421 Query: 131 GTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVD 190 GTGK++LA AVA ATFFS+ AS L SKY G+S KL+ ALF +A++ + SVIF+DE+D Sbjct: 422 GTGKTMLARAVATEAKATFFSISASSLTSKYLGDSEKLVRALFEVAKRQTCSVIFVDEID 481 Query: 191 SLTMKR---VSLDDAARRMIGTLL--------AEMDGFKERKDKVIVLTATNAPWDLDEA 239 S+ R + +++RR+ L A D +V+VL ATN PW +DEA Sbjct: 482 SILSARNDSGNEHESSRRLKTEFLIQWSSLTNAAPDKQTGHSPRVLVLAATNLPWCIDEA 541 Query: 240 MLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRL------YSGREIA 293 R R Y+PLP+ + + HL + ++ + L +E ++ L YSG +I Sbjct: 542 ARRRFVKRTYIPLPEKETRYK----HLSHLLHN-QVHCLTEEDLEELVNLTEGYSGSDIT 596 Query: 294 NVVKLATMKMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKK 353 + K A M L L D L ++ + P++L+ FK ++ I+ +++ + + Sbjct: 597 ALAKDAAMGPLR----NLGDALLTTSAE----MIPPISLNHFKASLRTIRPSVSQEGIHR 648 Query: 354 YERWAKEF 361 YE W K+F Sbjct: 649 YEEWNKQF 656 >sp|P40328|TBP6_YEAST PROBABLE 26S PROTEASE SUBUNIT YTA6 (TAT-BINDING HOMOLOG 6) >gi|531761|emb|CAA56959.1| (X81071) probable regulatory subunit of 26S protease [Saccharomyces cerevisiae] Length = 446 Score = 157 bits (392), Expect = 2e-37 Identities = 93/250 (37%), Positives = 143/250 (57%), Gaps = 26/250 (10%) Query: 84 LIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPI-----EPPQGILLFGPPGTGKSLLA 138 L+ + W DI GLR AK + +A+ + + EP +G+LLFGPPGTGK+++A Sbjct: 166 LVTDEKVYWEDIAGLRNAKNSLKEAVVYPFLRPDLFKGLREPVRGMLLFGPPGTGKTMIA 225 Query: 139 SAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDS-LTMKRV 197 AVA N+TFFSV AS LLSKY GES KL+ ALF +A++LSPS+IFIDE+DS LT + Sbjct: 226 KAVATESNSTFFSVSASSLLSKYLGESEKLVRALFYMAKKLSPSIIFIDEIDSMLTARSD 285 Query: 198 SLDDAARRMIGTLLAEMDGFKER-----------KDKVIVLTATNAPWDLDEAMLSRLPI 246 + ++++RR+ LL + +V+VL ATN PW +D+A R Sbjct: 286 NENESSRRIKTELLIQWSSLSSATAQSEDRNNTLDSRVLVLGATNLPWAIDDAARRRFSR 345 Query: 247 RIYVPLPDVNSAVEIFKIHLRGI--HYDVPLSRLAKEAVKRL---YSGREIANVVKLATM 301 ++Y+PLPD + + HL+ + L L E + + +SG ++ ++ K A M Sbjct: 346 KLYIPLPDYETRL----YHLKRLMAKQKNSLQDLDYELITEMTEGFSGSDLTSLAKEAAM 401 Query: 302 KMLEEMNPEL 311 + + ++ +L Sbjct: 402 EPIRDLGDKL 411 >sp|Q58576|PRS1_METJA PROTEASOME-ACTIVATING NUCLEOTIDASE (PAN) (26S PROTEASE REGULATORY SUBUNIT HOMOLOG) >gi|2127779|pir||G64446 ATP-dependent 26S proteosome regulatory subunit 4 homolog - Methanococcus jannaschii >gi|1591803|gb|AAB99179.1| (U67559) proteasome regulatory AAA-ATPase [Methanococcus jannaschii] Length = 430 Score = 157 bits (392), Expect = 2e-37 Identities = 107/281 (38%), Positives = 152/281 (54%), Gaps = 36/281 (12%) Query: 76 EYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGP 129 +Y K + +R + + DIGGL + + I + + L + K IEPP+GILL+GP Sbjct: 153 DYRAKAMEVDERPNVRYEDIGGLEKQMQEIREVVELPLKHPELFEKVGIEPPKGILLYGP 212 Query: 130 PGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEV 189 PGTGK+LLA AVA NATF V S+L+ K+ GE + L+ +F LA++ +PS+IFIDE+ Sbjct: 213 PGTGKTLLAKAVATETNATFIRVVGSELVKKFIGEGASLVKDIFKLAKEKAPSIIFIDEI 272 Query: 190 DSLTMKRVSL----DDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SR 243 D++ KR D +R + LLAEMDGF R D V ++ ATN P LD A+L R Sbjct: 273 DAIAAKRTDALTGGDREVQRTLMQLLAEMDGFDARGD-VKIIGATNRPDILDPAILRPGR 331 Query: 244 LPIRIYVPLPDVNSAVEIFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATM 301 I VP PD +EI KIH R ++ DV L +AK + G E+ + A M Sbjct: 332 FDRIIEVPAPDEKGRLEILKIHTRKMNLAEDVNLEEIAK--MTEGCVGAELKAICTEAGM 389 Query: 302 KMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARI 342 + E+ RD +T+DDF+ A+ +I Sbjct: 390 NAIREL---------------RDY----VTMDDFRKAVEKI 411 >pir||T39584 hypothetical protein SPBC16E9.10c - fission yeast (Schizosaccharomyces pombe) >gi|2467272|emb|CAB16902.1| (Z99759) AAA ATPase [Schizosaccharomyces pombe] Length = 779 Score = 156 bits (391), Expect = 3e-37 Identities = 103/292 (35%), Positives = 158/292 (53%), Gaps = 28/292 (9%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 ++WN+IG L+ + + AI I + I P G+LL+GPPG GK+LLA AVAN Sbjct: 489 VSWNNIGALKSIRVELQMAIVQPIKRPELYQSVGISAPTGVLLWGPPGCGKTLLAKAVAN 548 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR-VSLDDA 202 A F S++ +LL+KY GES + + +F AR SP VIF DE+D++ +R SL +A Sbjct: 549 ESKANFISIRGPELLNKYVGESERAVRQVFLRARASSPCVIFFDELDAMVPRRDDSLSEA 608 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVE 260 + R++ TLL E+DG +R V V+ ATN P +D AML RL + V LPD + VE Sbjct: 609 SSRVVNTLLTELDGLSDRSG-VYVIAATNRPDIIDPAMLRPGRLDKTLLVDLPDAHERVE 667 Query: 261 IFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEM--------NPE 310 I K + +H +V L L ++ +SG ++A +V+ A + L PE Sbjct: 668 ILKTLTKQTPLHEEVNLDVLGRDERCSNFSGADLAALVREAAVTALRSAVFADIASNEPE 727 Query: 311 LSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEFA 362 ++ + ++ +T DF+ A IK ++ D +KY+R AK ++ Sbjct: 728 ITQHSALEPIR--------VTNADFELAFKNIKPSVSDRDRQKYQRLAKRWS 771 Score = 115 bits (286), Expect = 6e-25 Identities = 86/263 (32%), Positives = 138/263 (51%), Gaps = 21/263 (7%) Query: 68 RKRREGKNEYFDKLKALIKR---STITWNDIGGLREAKKLIAQAIGLSIAKSP------- 117 RK R K + KA R S I+ +DIGGL + + + + + I K P Sbjct: 146 RKDRRSKTNGSKRQKAEANREPPSDISLSDIGGLDDCINELLELVAMPI-KHPEVYQYTG 204 Query: 118 IEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLAR 177 I PP+G+LL GPPG GK++LA+A+AN L F S+ A ++S GES K + +F A+ Sbjct: 205 IHPPRGVLLHGPPGCGKTMLANALANELGVPFISISAPSIVSGMSGESEKKVREVFEEAK 264 Query: 178 QLSPSVIFIDEVDSLTMKRVSLD-DAARRMIGTLLAEMD--GFKERKDK-VIVLTATNAP 233 L+P ++FIDE+D++T KR S + RR++ L MD F++ K V+V+ ATN P Sbjct: 265 SLAPCLMFIDEIDAVTPKRESAQREMERRIVAQFLTCMDELSFEKTDGKPVLVIGATNRP 324 Query: 234 WDLDEAM--LSRLPIRIYVPLPDVNSAVEIFKIHLRGIHY--DVPLSRLAKEAVKRLYSG 289 LD A+ R I + +P ++ +I + +G+ D +LAK+ Y G Sbjct: 325 DSLDSALRRAGRFDREICLTVPSQDAREKILRTMAKGLKLSGDFDFRQLAKQTPG--YVG 382 Query: 290 REIANVVKLATMKMLEEMNPELS 312 ++ + A + ++ + E+S Sbjct: 383 ADLKALTAAAGIIAIKRIFNEIS 405 >gi|11545833 fidgetin-like 1 [Homo sapiens] >gi|10434929|dbj|BAB14426.1| (AK023142) unnamed protein product [Homo sapiens] Length = 674 Score = 156 bits (391), Expect = 3e-37 Identities = 97/287 (33%), Positives = 161/287 (55%), Gaps = 29/287 (10%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSPI-----EPPQGILLFGPPGTGKSLLASAVANS 144 + W DI G+ AK I + + + + I PP+GILLFGPPGTGK+L+ +A+ Sbjct: 398 VNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQ 457 Query: 145 LNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD-DAA 203 ATFFS+ AS L SK+ GE K++ ALF++AR P+VIFIDE+DSL +R + +++ Sbjct: 458 SGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHESS 517 Query: 204 RRMIGTLLAEMDG-FKERKDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIF 262 RR+ L ++DG +D+++V+ ATN P ++DEA RL R+Y+PLP+ ++ +I Sbjct: 518 RRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIV 577 Query: 263 KIHLRGIHYDVPLSRLAKEAVKR--LYSGREIANVVKLATMKMLEEMNPELSDPLRVSTL 320 I+L ++ V++ +SG ++ + + A++ P+R +L Sbjct: 578 -INLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCRGASL-----------GPIR--SL 623 Query: 321 KGRDLTT------RPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 + D+ T RP+ DF+ A ++ ++ D++ YE W K F Sbjct: 624 QTADIATITPDQVRPIAYIDFENAFRTVRPSVSPKDLELYENWNKTF 670 >sp|P54812|TER2_CAEEL TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE HOMOLOG 2 (P97/CDC48 HOMOLOG 2) >gi|7497271|pir||T19879 hypothetical protein C41C4.8 - Caenorhabditis elegans >gi|3874892|emb|CAA88105.1| (Z48045) contains similarity to Pfam domain: PF00004 (ATPases associated with various cellular activities (AAA)), Score=656.9, E-value=3.5e-194, N=2~cDNA EST EMBL:M89239 comes from this gene; cDNA EST yk9e6.3 comes from this gene~cDNA EST yk9e6.5 comes> >gi|3875715|emb|CAA88314.1| (Z48334) contains similarity to Pfam domain: PF00004 (ATPases associated with various cellular activities (AAA)), Score=656.9, E-value=3.5e-194, N=2~cDNA EST EMBL:M89239 comes from this gene; cDNA EST yk9e6.3 comes from this gene~cDNA EST yk9e6.5 comes> Length = 810 Score = 156 bits (390), Expect = 4e-37 Identities = 110/313 (35%), Positives = 172/313 (54%), Gaps = 31/313 (9%) Query: 73 GKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILL 126 GK+ +A+++ TW+DIGGL+ K+ + + + + K ++P +G+L Sbjct: 462 GKSSPSALREAVVETPNTTWSDIGGLQNVKRELQELVQYPVEHPEKYLKFGMQPSRGVLF 521 Query: 127 FGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFI 186 +GPPG GK+LLA A+AN A F S+K +LL+ +FGES + +F AR +P V+F Sbjct: 522 YGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDVFDKARAAAPCVLFF 581 Query: 187 DEVDSLTMKR-VSLDD---AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML- 241 DE+DS+ R S+ D AA R+I +L EMDG +K+ V ++ ATN P +D A+L Sbjct: 582 DELDSIAKARGGSVGDAGGAADRVINQVLTEMDGMNAKKN-VFIIGATNRPDIIDPAVLR 640 Query: 242 -SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANV--- 295 RL IY+PLPD S ++IFK LR + D+ L+ LAK V +SG ++ + Sbjct: 641 PGRLDQLIYIPLPDEASRLQIFKASLRKTPLSADLDLNFLAKNTVG--FSGADLTEICQR 698 Query: 296 -VKLATMKMLE-EMNPELSDPLRVSTLKGRDLTTRPL-------TLDDFKYAMARIKSPI 346 KLA + +E E+ E R + +G +L L T F+ AM + + Sbjct: 699 ACKLAIRESIEREIRQEKERQDR--SARGEELMEDELADPVPEITRAHFEEAMKFARRSV 756 Query: 347 TKSDVKKYERWAK 359 T +D++KYE +A+ Sbjct: 757 TDNDIRKYEMFAQ 769 Score = 139 bits (347), Expect = 4e-32 Identities = 87/263 (33%), Positives = 147/263 (55%), Gaps = 16/263 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 + ++D+GG+R+ I + + L + ++PP+GILLFGPPGTGK+L+A AVAN Sbjct: 206 VGYDDLGGVRKQLAQIKEMVELPLRHPQLFKAIGVKPPRGILLFGPPGTGKTLIARAVAN 265 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL-DDA 202 A FF + +++SK GES + F+ + SP+++FIDE+D++ KR + Sbjct: 266 ETGAFFFLINGPEIMSKMSGESESNLRKAFAECEKNSPAILFIDEIDAIAPKREKAHGEV 325 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSAVE 260 +R++ LL MDG K R V+V+ ATN P +D A+ R I + +PD +E Sbjct: 326 EKRIVSQLLTLMDGLKTRA-HVVVIAATNRPNSIDGALRRFGRFDREIDIGIPDAVGRLE 384 Query: 261 IFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 I +IH + + DV L ++A E + G ++A++ A ++ + E EL D L Sbjct: 385 ILRIHTKNMKLGEDVDLEQVANEC--HGFVGADLASLCSEAAIQQIRE-KMELID-LEDD 440 Query: 319 TLKGRDLTTRPLTLDDFKYAMAR 341 T+ L + +T+++F++AM + Sbjct: 441 TIDAEVLNSLAVTMENFRFAMGK 463 >gi|6678559 valosin containing protein; homolog of yeast cdc48 (S. cerevisiae) [Mus musculus] >gi|400712|sp|Q01853|TERA_MOUSE TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE (TER ATPASE) (15S MG(2+)-ATPASE P97 SUBUNIT) (VALOSIN CONTAINING PROTEIN) (VCP) [CONTAINS: VALOSIN] >gi|284979|pir||S25197 transitional endoplasmic reticulum ATPase - mouse >gi|55217|emb|CAA78412.1| (Z14044) murine valosin-containing protein [Mus musculus] Length = 806 Score = 155 bits (389), Expect = 5e-37 Identities = 104/298 (34%), Positives = 165/298 (54%), Gaps = 23/298 (7%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKS 135 + +++ +TW DIGGL + K+ + + + + K + P +G+L +GPPG GK+ Sbjct: 466 ETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKT 525 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 LLA A+AN A F S+K +LL+ +FGES + +F ARQ +P V+F DE+DS+ Sbjct: 526 LLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKA 585 Query: 196 R-VSLDD---AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIY 249 R ++ D AA R+I +L EMDG +K+ V ++ ATN P +D A+L RL IY Sbjct: 586 RGGNIGDGGGAADRVINQILTEMDGMSTKKN-VFIIGATNRPDIIDPAILRPGRLDQLIY 644 Query: 250 VPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANV----VKLATMKM 303 +PLPD S V I K +LR + DV L LAK + +SG ++ + KLA + Sbjct: 645 IPLPDEKSRVAILKANLRKSPVAKDVDLEFLAK--MTNGFSGADLTEICQRACKLAIRES 702 Query: 304 LE-EMNPELSDPLRVSTLKGRDLTTRP-LTLDDFKYAMARIKSPITKSDVKKYERWAK 359 +E E+ E S ++ + P + D F+ AM + ++ +D++KYE +A+ Sbjct: 703 IESEIRRERERQTNPSAMEVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQ 760 Score = 138 bits (344), Expect = 1e-31 Identities = 86/263 (32%), Positives = 147/263 (55%), Gaps = 16/263 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 + ++D+GG R+ I + + L + ++PP+GILL+GPPGTGK+L+A AVAN Sbjct: 201 VGYDDVGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVAN 260 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL-DDA 202 A FF + +++SK GES + F A + +P++IFIDE+D++ KR + Sbjct: 261 ETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEV 320 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSAVE 260 RR++ LL MDG K+R VIV+ ATN P +D A+ R + + +PD +E Sbjct: 321 ERRIVSQLLTLMDGLKQRA-HVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLE 379 Query: 261 IFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 I +IH + + DV L ++A E + G ++A + A ++ + + +L D L Sbjct: 380 ILQIHTKNMKLADDVDLEQVANET--HGHVGADLAALCSEAALQAIRK-KMDLID-LEDE 435 Query: 319 TLKGRDLTTRPLTLDDFKYAMAR 341 T+ + + +T+DDF++A+++ Sbjct: 436 TIDAEVMNSLAVTMDDFRWALSQ 458 >pir||VPPG transitional endoplasmic reticulum ATPase - pig >gi|225450|prf||1303334A valosin precursor [Sus scrofa domestica] Length = 806 Score = 155 bits (389), Expect = 5e-37 Identities = 104/298 (34%), Positives = 165/298 (54%), Gaps = 23/298 (7%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKS 135 + +++ +TW DIGGL + K+ + + + + K + P +G+L +GPPG GK+ Sbjct: 466 ETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKT 525 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 LLA A+AN A F S+K +LL+ +FGES + +F ARQ +P V+F DE+DS+ Sbjct: 526 LLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKA 585 Query: 196 R-VSLDD---AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIY 249 R ++ D AA R+I +L EMDG +K+ V ++ ATN P +D A+L RL IY Sbjct: 586 RGGNIGDGGGAADRVINQILTEMDGMSTKKN-VFIIGATNRPDIIDPAILRPGRLDQLIY 644 Query: 250 VPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANV----VKLATMKM 303 +PLPD S V I K +LR + DV L LAK + +SG ++ + KLA + Sbjct: 645 IPLPDEKSRVAILKANLRKSPVAKDVDLEFLAK--MTNGFSGADLTEICQRACKLAIRES 702 Query: 304 LE-EMNPELSDPLRVSTLKGRDLTTRP-LTLDDFKYAMARIKSPITKSDVKKYERWAK 359 +E E+ E S ++ + P + D F+ AM + ++ +D++KYE +A+ Sbjct: 703 IESEIRRERERQTNPSAMEVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQ 760 Score = 138 bits (345), Expect = 8e-32 Identities = 87/263 (33%), Positives = 147/263 (55%), Gaps = 16/263 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 + ++DIGG R+ I + + L + ++PP+GILL+GPPGTGK+L+A AVAN Sbjct: 201 VGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVAN 260 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL-DDA 202 A FF + +++SK GES + F A + +P++IFIDE+D++ KR + Sbjct: 261 ETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEV 320 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSAVE 260 RR++ LL MDG K+R VIV+ ATN P +D A+ R + + +PD +E Sbjct: 321 ERRIVSQLLTLMDGLKQRA-HVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLE 379 Query: 261 IFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 I +IH + + DV L ++A E + G ++A + A ++ + + +L D L Sbjct: 380 ILQIHTKNMKLADDVDLEQVANET--HGHVGADLAALCSEAALQAIRK-KMDLID-LEDE 435 Query: 319 TLKGRDLTTRPLTLDDFKYAMAR 341 T+ + + +T+DDF++A+++ Sbjct: 436 TIDAEVMNSLAVTMDDFRWALSQ 458 >sp|P46462|TERA_RAT TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE (TER ATPASE) (15S MG(2+)-ATPASE P97 SUBUNIT) (VALOSIN CONTAINING PROTEIN) (VCP) [CONTAINS: VALOSIN] >gi|1083817|pir||A55190 transitional endoplasmic reticulum ATPase (EC 3.6.1.-) [validated] - rat >gi|641973|gb|AAC52154.1| (U11760) transitional endoplasmic reticulum ATPase [Rattus norvegicus] >gi|1093322|prf||2103265A transitional endoplasmic reticulum ATPase [Rattus norvegicus] Length = 806 Score = 155 bits (389), Expect = 5e-37 Identities = 104/298 (34%), Positives = 165/298 (54%), Gaps = 23/298 (7%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKS 135 + +++ +TW DIGGL + K+ + + + + K + P +G+L +GPPG GK+ Sbjct: 466 ETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKT 525 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 LLA A+AN A F S+K +LL+ +FGES + +F ARQ +P V+F DE+DS+ Sbjct: 526 LLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKA 585 Query: 196 R-VSLDD---AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIY 249 R ++ D AA R+I +L EMDG +K+ V ++ ATN P +D A+L RL IY Sbjct: 586 RGGNIGDGGGAADRVINQILTEMDGMSTKKN-VFIIGATNRPDIIDPAILRPGRLDQLIY 644 Query: 250 VPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANV----VKLATMKM 303 +PLPD S V I K +LR + DV L LAK + +SG ++ + KLA + Sbjct: 645 IPLPDEKSRVAILKANLRKSPVAKDVDLEFLAK--MTNGFSGADLTEICQRACKLAIRES 702 Query: 304 LE-EMNPELSDPLRVSTLKGRDLTTRP-LTLDDFKYAMARIKSPITKSDVKKYERWAK 359 +E E+ E S ++ + P + D F+ AM + ++ +D++KYE +A+ Sbjct: 703 IESEIRRERERQTNPSAMEVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQ 760 Score = 138 bits (345), Expect = 8e-32 Identities = 87/263 (33%), Positives = 147/263 (55%), Gaps = 16/263 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 + ++DIGG R+ I + + L + ++PP+GILL+GPPGTGK+L+A AVAN Sbjct: 201 VGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVAN 260 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL-DDA 202 A FF + +++SK GES + F A + +P++IFIDE+D++ KR + Sbjct: 261 ETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEV 320 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSAVE 260 RR++ LL MDG K+R VIV+ ATN P +D A+ R + + +PD +E Sbjct: 321 ERRIVSQLLTLMDGLKQRA-HVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLE 379 Query: 261 IFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 I +IH + + DV L ++A E + G ++A + A ++ + + +L D L Sbjct: 380 ILQIHTKNMKLADDVDLEQVANET--HGHVGADLAALCSEAALQAIRK-KMDLID-LEDE 435 Query: 319 TLKGRDLTTRPLTLDDFKYAMAR 341 T+ + + +T+DDF++A+++ Sbjct: 436 TIDAEVMNSLAVTMDDFRWALSQ 458 >gi|6005942 valosin-containing protein [Homo sapiens] >gi|11429568|ref|XP_005631.1| valosin-containing protein [Homo sapiens] >gi|6094447|sp|P55072|TERA_HUMAN TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE (TER ATPASE) (15S MG(2+)-ATPASE P97 SUBUNIT) (VALOSIN CONTAINING PROTEIN) (VCP) [CONTAINS: VALOSIN] >gi|7435756|pir||T02243 probable transitional endoplasmic reticulum ATPase - human >gi|2984586|gb|AAC07984.1| (AC004472) TERA_HUMAN [Homo sapiens] >gi|5410290|gb|AAD43016.1| (AF100752) transitional endoplasmic reticulum ATPase [Homo sapiens] Length = 806 Score = 155 bits (389), Expect = 5e-37 Identities = 104/298 (34%), Positives = 165/298 (54%), Gaps = 23/298 (7%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKS 135 + +++ +TW DIGGL + K+ + + + + K + P +G+L +GPPG GK+ Sbjct: 466 ETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKT 525 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 LLA A+AN A F S+K +LL+ +FGES + +F ARQ +P V+F DE+DS+ Sbjct: 526 LLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKA 585 Query: 196 R-VSLDD---AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIY 249 R ++ D AA R+I +L EMDG +K+ V ++ ATN P +D A+L RL IY Sbjct: 586 RGGNIGDGGGAADRVINQILTEMDGMSTKKN-VFIIGATNRPDIIDPAILRPGRLDQLIY 644 Query: 250 VPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANV----VKLATMKM 303 +PLPD S V I K +LR + DV L LAK + +SG ++ + KLA + Sbjct: 645 IPLPDEKSRVAILKANLRKSPVAKDVDLEFLAK--MTNGFSGADLTEICQRACKLAIRES 702 Query: 304 LE-EMNPELSDPLRVSTLKGRDLTTRP-LTLDDFKYAMARIKSPITKSDVKKYERWAK 359 +E E+ E S ++ + P + D F+ AM + ++ +D++KYE +A+ Sbjct: 703 IESEIRRERERQTNPSAMEVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQ 760 Score = 138 bits (345), Expect = 8e-32 Identities = 87/263 (33%), Positives = 147/263 (55%), Gaps = 16/263 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 + ++DIGG R+ I + + L + ++PP+GILL+GPPGTGK+L+A AVAN Sbjct: 201 VGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVAN 260 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL-DDA 202 A FF + +++SK GES + F A + +P++IFIDE+D++ KR + Sbjct: 261 ETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEV 320 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSAVE 260 RR++ LL MDG K+R VIV+ ATN P +D A+ R + + +PD +E Sbjct: 321 ERRIVSQLLTLMDGLKQRA-HVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLE 379 Query: 261 IFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 I +IH + + DV L ++A E + G ++A + A ++ + + +L D L Sbjct: 380 ILQIHTKNMKLADDVDLEQVANET--HGHVGADLAALCSEAALQAIRK-KMDLID-LEDE 435 Query: 319 TLKGRDLTTRPLTLDDFKYAMAR 341 T+ + + +T+DDF++A+++ Sbjct: 436 TIDAEVMNSLAVTMDDFRWALSQ 458 >pir||T06669 hypothetical protein F6I7.60 - Arabidopsis thaliana >gi|4678264|emb|CAB41125.1| (AL049657) putative protein [Arabidopsis thaliana] >gi|7269336|emb|CAB79395.1| (AL161562) putative protein [Arabidopsis thaliana] Length = 442 Score = 155 bits (389), Expect = 5e-37 Identities = 94/291 (32%), Positives = 166/291 (56%), Gaps = 23/291 (7%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSPI-------EPPQGILLFGPPGTGKSLLASAVA 142 +T++DIG L + K ++ + + L + + + +P +GILLFGPPGTGK++LA AVA Sbjct: 137 VTFDDIGALEKVKDILKELVMLPLQRPELFCKGELTKPCKGILLFGPPGTGKTMLAKAVA 196 Query: 143 NSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR--VSLD 200 +A F ++ S + SK+FGE K + A+FSLA ++SPSVIF+DEVDS+ +R Sbjct: 197 KEADANFINISMSSITSKWFGEGEKYVKAVFSLASKMSPSVIFVDEVDSMLGRREHPREH 256 Query: 201 DAARRMIGTLLAEMDGF-KERKDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAV 259 +A+R++ + DG + +++V+VL ATN P+DLDEA++ RLP R+ V LPD ++ Sbjct: 257 EASRKIKNEFMMHWDGLTTQERERVLVLAATNRPFDLDEAVIRRLPRRLMVGLPDTSNRA 316 Query: 260 EIFKIHL--RGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRV 317 I K+ L + D+ + +A ++ YSG ++ N+ A + ++E+ + Sbjct: 317 FILKVILAKEDLSPDLDIGEIA--SMTNGYSGSDLKNLCVTAAHRPIKEILEKEKRERDA 374 Query: 318 STLKGR-------DLTTRPLTLDDFKYAMARIKSPIT--KSDVKKYERWAK 359 + +G+ R L ++DF+ A + + ++ + + ++W K Sbjct: 375 ALAQGKVPPPLSGSSDLRALNVEDFRDAHKWVSASVSSESATMTALQQWNK 425 >pir||T46437 hypothetical protein DKFZp434K0126.1 - human (fragment) >gi|6807907|emb|CAB70717.1| (AL137377) hypothetical protein [Homo sapiens] Length = 431 Score = 155 bits (389), Expect = 5e-37 Identities = 104/298 (34%), Positives = 165/298 (54%), Gaps = 23/298 (7%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKS 135 + +++ +TW DIGGL + K+ + + + + K + P +G+L +GPPG GK+ Sbjct: 91 ETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKT 150 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 LLA A+AN A F S+K +LL+ +FGES + +F ARQ +P V+F DE+DS+ Sbjct: 151 LLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKA 210 Query: 196 R-VSLDD---AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIY 249 R ++ D AA R+I +L EMDG +K+ V ++ ATN P +D A+L RL IY Sbjct: 211 RGGNIGDGGGAADRVINQILTEMDGMSTKKN-VFIIGATNRPDIIDPAILRPGRLDQLIY 269 Query: 250 VPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANV----VKLATMKM 303 +PLPD S V I K +LR + DV L LAK + +SG ++ + KLA + Sbjct: 270 IPLPDEKSRVAILKANLRKSPVAKDVDLEFLAK--MTNGFSGADLTEICQRACKLAIRES 327 Query: 304 LE-EMNPELSDPLRVSTLKGRDLTTRP-LTLDDFKYAMARIKSPITKSDVKKYERWAK 359 +E E+ E S ++ + P + D F+ AM + ++ +D++KYE +A+ Sbjct: 328 IESEIRRERERQTNPSAMEVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQ 385 >sp|P03974|TERA_PIG TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE (TER ATPASE) (15S MG(2+)-ATPASE P97 SUBUNIT) (VALOSIN CONTAINING PROTEIN) (VCP) [CONTAINS: VALOSIN (PEPTIDE VQY)] >gi|164726|gb|AAA31142.1| (M30143) valosin-containing protein [Sus scrofa] Length = 806 Score = 155 bits (387), Expect = 9e-37 Identities = 104/298 (34%), Positives = 164/298 (54%), Gaps = 23/298 (7%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKS 135 + +++ +TW DIGGL + K+ + + + K + P +G+L +GPPG GK+ Sbjct: 466 ETVVEVPQVTWEDIGGLEDVKRELQDLVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKT 525 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 LLA A+AN A F S+K +LL+ +FGES + +F ARQ +P V+F DE+DS+ Sbjct: 526 LLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKA 585 Query: 196 R-VSLDD---AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIY 249 R ++ D AA R+I +L EMDG +K+ V ++ ATN P +D A+L RL IY Sbjct: 586 RGGNIGDGGGAADRVINQILTEMDGMSTKKN-VFIIGATNRPDIIDPAILRPGRLDQLIY 644 Query: 250 VPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANV----VKLATMKM 303 +PLPD S V I K +LR + DV L LAK + +SG ++ + KLA + Sbjct: 645 IPLPDEKSRVAILKANLRKSPVAKDVDLEFLAK--MTNGFSGADLTEICQRACKLAIRES 702 Query: 304 LE-EMNPELSDPLRVSTLKGRDLTTRP-LTLDDFKYAMARIKSPITKSDVKKYERWAK 359 +E E+ E S ++ + P + D F+ AM + ++ +D++KYE +A+ Sbjct: 703 IESEIRRERERQTNPSAMEVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQ 760 Score = 138 bits (345), Expect = 8e-32 Identities = 87/263 (33%), Positives = 147/263 (55%), Gaps = 16/263 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 + ++DIGG R+ I + + L + ++PP+GILL+GPPGTGK+L+A AVAN Sbjct: 201 VGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVAN 260 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL-DDA 202 A FF + +++SK GES + F A + +P++IFIDE+D++ KR + Sbjct: 261 ETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEV 320 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSAVE 260 RR++ LL MDG K+R VIV+ ATN P +D A+ R + + +PD +E Sbjct: 321 ERRIVSQLLTLMDGLKQRA-HVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLE 379 Query: 261 IFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 I +IH + + DV L ++A E + G ++A + A ++ + + +L D L Sbjct: 380 ILQIHTKNMKLADDVDLEQVANET--HGHVGADLAALCSEAALQAIRK-KMDLID-LEDE 435 Query: 319 TLKGRDLTTRPLTLDDFKYAMAR 341 T+ + + +T+DDF++A+++ Sbjct: 436 TIDAEVMNSLAVTMDDFRWALSQ 458 >dbj|BAB09730.1| (AB015476) 26S proteasome regulatory particle chain RPT6-like protein [Arabidopsis thaliana] Length = 403 Score = 155 bits (387), Expect = 9e-37 Identities = 106/307 (34%), Positives = 166/307 (53%), Gaps = 27/307 (8%) Query: 55 EEAKKWEEKAKNVRKRREGK----NEYFDKLKALIKRST---ITWNDIGGLREAKKLIAQ 107 + AKK E + + KR N+Y D + + + + IGGL K+ + + Sbjct: 42 DAAKKSLEHKREIAKRLGRPLIQTNQYEDVIACDVINPLHIDVEFGSIGGLESIKQALYE 101 Query: 108 AIGLSIAKSPI-------EPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSK 160 + L + + + P +G+LL+GPPGTGK++LA A+A A F +VK S+L+SK Sbjct: 102 LVILPLKRPELFAYGKLLGPQKGVLLYGPPGTGKTMLAKAIARESEAVFINVKVSNLMSK 161 Query: 161 YFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDAARRMIGT-LLAEMDGF-K 218 +FG++ KL+SA+FSLA +L P++IFIDEVDS +R S D+ A + T +A DGF Sbjct: 162 WFGDAQKLVSAVFSLAYKLQPAIIFIDEVDSFLGQRRSTDNEAMSNMKTEFMALWDGFTT 221 Query: 219 ERKDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRG--IHYDVPLS 276 ++ +V+VL ATN P +LDEA+L R P + +PD +I K+ L+G + D+ Sbjct: 222 DQNARVMVLAATNRPSELDEAILRRFPQSFEIGMPDCQERAQILKVVLKGESVESDINYD 281 Query: 277 RLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFK 336 R+A+ + Y+G +I + K A + E+ + RVS RPLT D + Sbjct: 282 RIAR--LCEDYTGSDIFELCKKAAYFPIREILEAEKEGKRVS-------VPRPLTQLDLE 332 Query: 337 YAMARIK 343 +A K Sbjct: 333 KVLATSK 339 >pir||G71242 probable 26S proteinase regulatory subunit - Pyrococcus horikoshii >gi|3256587|dbj|BAA29270.1| (AP000001) 399aa long hypothetical 26S protease regulatory subunit [Pyrococcus horikoshii] Length = 399 Score = 154 bits (386), Expect = 1e-36 Identities = 93/230 (40%), Positives = 138/230 (59%), Gaps = 19/230 (8%) Query: 84 LIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFGPPGTGKSL 136 +I+R +T+NDIGGL++ + + +AI L + K P I+PP+G+LL+GPPG GK+L Sbjct: 131 VIERPNVTYNDIGGLKKQLQELREAIELPL-KHPELFEEVGIDPPKGVLLYGPPGCGKTL 189 Query: 137 LASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR 196 +A A+A+ +NATF V S+L+ KY GE ++L+ LF LA++ +P++IFIDE+D++ KR Sbjct: 190 MAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKR 249 Query: 197 VSLDDAARRMIG----TLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYV 250 + R + LLAEMDGF R V V+ ATN P LD A+L R I V Sbjct: 250 MDETTGGEREVNRTLMQLLAEMDGFDPR-GNVKVIAATNRPDILDPALLRPGRFDRLIEV 308 Query: 251 PLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLAT 300 PLPD +EI K+H R + L + A+ + G A++ +AT Sbjct: 309 PLPDFEGRLEILKVHTR----RMKLKGVDLRAIAEMTEGASGADLKAIAT 354 >gb|AAB40928.2| (U83085) cell division cycle protein 48 [Dictyostelium discoideum] Length = 793 Score = 154 bits (386), Expect = 1e-36 Identities = 101/299 (33%), Positives = 160/299 (52%), Gaps = 24/299 (8%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKS 135 + +++ T TW DIGGL K+ + + + + K ++P +G+L +GPPG GK+ Sbjct: 464 ETVVEVPTTTWEDIGGLEGVKRELRETVQYPVEHPEKFRKFGMQPSKGVLFYGPPGCGKT 523 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 LLA A+AN A F S+K +LL+ +FGES + LF ARQ +P V+F DE+DS+ Sbjct: 524 LLAKAIANECQANFISIKGPELLTMWFGESEANVRELFDKARQAAPCVLFFDELDSIARS 583 Query: 196 RVS----LDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIY 249 R S A R+I +L EMDG +K+ V ++ ATN P +D A+L RL IY Sbjct: 584 RGSSQGDAGGAGDRVINQILTEMDGMNAKKN-VFIIGATNRPDIIDPAILRPGRLDQLIY 642 Query: 250 VPLPDVNSAVEIFK--IHLRGIHYDVPLSRLAKEAVKRLYSGREIANV----VKLATMKM 303 +PLPD+ S V I K ++ + DV L L ++ + +SG ++ + KLA + Sbjct: 643 IPLPDLPSRVAILKACLNKSPVAKDVDLEFLGQKT--QGFSGADLTEICQRACKLAIRES 700 Query: 304 LEEMNPELSDPLRVSTLKGRDLTTRP---LTLDDFKYAMARIKSPITKSDVKKYERWAK 359 +E+ K D + P +T D F+ AM + ++ +D++KYE +A+ Sbjct: 701 IEKDIESTKARQESGDTKMEDDSVDPVPEITRDHFQEAMRSARRSVSDNDIRKYESFAQ 759 Score = 134 bits (334), Expect = 1e-30 Identities = 87/261 (33%), Positives = 138/261 (52%), Gaps = 16/261 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 + ++DIGG+R+ I + + L + ++PP+GILL+GPPG GK+++A AVAN Sbjct: 199 VGYDDIGGVRKQLGQIRELVELPLRHPQLFKNIGVKPPKGILLYGPPGCGKTMIARAVAN 258 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD-DA 202 A FF + +++SK GES + F A + +PS+IFIDE+DS+ KR + Sbjct: 259 ETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTQGEV 318 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSAVE 260 RR++ LL MDG K R VIV+ ATN P +D A+ R I + +PD +E Sbjct: 319 ERRIVSQLLTLMDGLKSRA-HVIVMGATNRPNSIDPALRRFGRFDREIDITIPDATGRLE 377 Query: 261 IFKIHLRGIHYD--VPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 I +IH + + D V L +A E Y G ++A + + ++ + E + L Sbjct: 378 IMRIHTKNMKLDETVDLEAVANET--HGYVGADLAALCTESALQCIREKMDVID--LEDE 433 Query: 319 TLKGRDLTTRPLTLDDFKYAM 339 T+ L + +T D F+ A+ Sbjct: 434 TISAEILESMSVTQDHFRTAL 454 >pir||H75207 26s proteinase regulatory chain 4 PAB2233 - Pyrococcus abyssi (strain Orsay) >gi|5457620|emb|CAB49111.1| (AJ248283) 26S protease regulatory subunit 4 [Pyrococcus abyssi] Length = 399 Score = 153 bits (384), Expect = 2e-36 Identities = 92/230 (40%), Positives = 137/230 (59%), Gaps = 19/230 (8%) Query: 84 LIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFGPPGTGKSL 136 +I+R +T+NDIGGL++ + + +AI L + K P I+PP+G+LL+GPPG GK+L Sbjct: 131 VIERPNVTYNDIGGLKKQLQELREAIELPL-KHPELFEEVGIDPPKGVLLYGPPGCGKTL 189 Query: 137 LASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR 196 +A A+A+ +NATF V S+L+ KY GE ++L+ LF LA++ +P++IFIDE+D++ KR Sbjct: 190 MAKALAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKR 249 Query: 197 VSLDDAARRMIG----TLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYV 250 + R + LLAEMDGF R V V+ ATN P LD A+L R I V Sbjct: 250 MDETTGGEREVNRTLMQLLAEMDGFDPR-GNVKVIAATNRPDILDPALLRPGRFDRLIEV 308 Query: 251 PLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLAT 300 PLPD +EI K+H R + L + + + G A++ +AT Sbjct: 309 PLPDFEGRLEILKVHTR----RMKLKNVDLRVIAEITEGASGADLKAIAT 354 >gi|6320077 microsomal ATPase; Cdc48p [Saccharomyces cerevisiae] >gi|1705679|sp|P25694|CC48_YEAST CELL DIVISION CONTROL PROTEIN 48 >gi|2118116|pir||S67669 transitional endoplasmic reticulum ATPase [validated] - yeast (Saccharomyces cerevisiae) >gi|1431189|emb|CAA98694.1| (Z74174) ORF YDL126c [Saccharomyces cerevisiae] >gi|1449400|emb|CAA40276.1| (X56956) CDC48p [Saccharomyces cerevisiae] Length = 835 Score = 153 bits (383), Expect = 3e-36 Identities = 100/309 (32%), Positives = 165/309 (53%), Gaps = 31/309 (10%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSI------AKSPIEPPQGILLFGPPGTGKS 135 + +++ +TW+D+GGL E K+ + + + + K + P +G+L +GPPGTGK+ Sbjct: 476 ETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKT 535 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 LLA AVA ++A F SVK +LLS ++GES I +F AR +P+V+F+DE+DS+ Sbjct: 536 LLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKA 595 Query: 196 R-VSLDD---AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIY 249 R SL D A+ R++ LL EMDG +K+ V V+ ATN P +D A+L RL IY Sbjct: 596 RGGSLGDAGGASDRVVNQLLTEMDGMNAKKN-VFVIGATNRPDQIDPAILRPGRLDQLIY 654 Query: 250 VPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEE--- 306 VPLPD N+ + I LR + L A + +SG ++ +V+ A +++ Sbjct: 655 VPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIE 714 Query: 307 --MNPELSDPLRVS------TLKGRDLTTRP-------LTLDDFKYAMARIKSPITKSDV 351 E ++V T +G P +T + F AM K ++ +++ Sbjct: 715 AHRQHEAEKEVKVEGEDVEMTDEGAKAEQEPEVDPVPYITKEHFAEAMKTAKRSVSDAEL 774 Query: 352 KKYERWAKE 360 ++YE ++++ Sbjct: 775 RRYEAYSQQ 783 Score = 141 bits (353), Expect = 9e-33 Identities = 89/261 (34%), Positives = 145/261 (55%), Gaps = 16/261 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 + ++DIGG R+ I + + L + I+PP+G+L++GPPGTGK+L+A AVAN Sbjct: 211 VGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVAN 270 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD-DA 202 A FF + +++SK GES + F A + +P++IFIDE+DS+ KR + + Sbjct: 271 ETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEV 330 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSAVE 260 RR++ LL MDG K R + V+V+ ATN P +D A+ R + + +PD +E Sbjct: 331 ERRVVSQLLTLMDGMKARSN-VVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLE 389 Query: 261 IFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 + +IH + + DV L LA E Y G +IA++ A M+ + E +L D L Sbjct: 390 VLRIHTKNMKLADDVDLEALAAET--HGYVGADIASLCSEAAMQQIRE-KMDLID-LDED 445 Query: 319 TLKGRDLTTRPLTLDDFKYAM 339 + L + +T+D+F++A+ Sbjct: 446 EIDAEVLDSLGVTMDNFRFAL 466 >sp|P23787|TERA_XENLA TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE (TER ATPASE) (15S MG(2+)-ATPASE P97 SUBUNIT) >gi|104084|pir||S19738 transitional endoplasmic reticulum ATPase (EC 3.6.1.-) 97K chain - African clawed frog >gi|64966|emb|CAA38146.1| (X54240) p97 subunit of 15S Mg(2+)- ATPase [Xenopus laevis] Length = 805 Score = 153 bits (382), Expect = 4e-36 Identities = 102/298 (34%), Positives = 165/298 (55%), Gaps = 23/298 (7%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKS 135 + +++ +TW DIGGL + K+ + + + + K + P +G+L +GPPG GK+ Sbjct: 466 ETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKT 525 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 LLA A+AN A F S+K +LL+ +FGES + +F ARQ +P V+F DE+DS+ Sbjct: 526 LLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKA 585 Query: 196 R-VSLDD---AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIY 249 R ++ D AA R+I +L EMDG +K+ V ++ ATN P +D A+L RL IY Sbjct: 586 RGGNIGDGGGAADRVINQILTEMDGMSIKKN-VFIIGATNRPDIIDPAILRPGRLDQLIY 644 Query: 250 VPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANV----VKLATMKM 303 +PLPD S + I K +LR + DV + LAK + +SG ++ + KLA + Sbjct: 645 IPLPDEKSRMAILKANLRKSPVAKDVDVDFLAK--MTNGFSGADLTEICQRACKLAIRES 702 Query: 304 LE-EMNPELSDPLRVSTLKGRDLTTRP-LTLDDFKYAMARIKSPITKSDVKKYERWAK 359 +E E+ E S ++ + P + D F+ AM + ++ +D++KYE +A+ Sbjct: 703 IENEIRRERDRQTNPSAMEVEEDDPVPEIRRDHFEEAMRLARRSVSDNDIRKYEMFAQ 760 Score = 136 bits (339), Expect = 4e-31 Identities = 86/263 (32%), Positives = 146/263 (54%), Gaps = 16/263 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 + ++DIGG R+ I + + L + ++PP+GILL+GPPGTGK+L+A AVAN Sbjct: 201 VGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVAN 260 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL-DDA 202 A FF + +++SK GES + F A + +P++IFIDE+D++ KR + Sbjct: 261 ETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEV 320 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSAVE 260 RR++ LL MDG K+R VIV+ ATN P +D A+ R + + +PD +E Sbjct: 321 ERRIVSQLLTLMDGLKQRA-HVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDSTGRLE 379 Query: 261 IFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 I +IH + + DV L ++A E + G ++A + A ++ + + +L D L Sbjct: 380 ILQIHTKNMKLSDDVDLEQVANET--HGHVGADLAALCSEAALQAIRK-KMDLID-LEDE 435 Query: 319 TLKGRDLTTRPLTLDDFKYAMAR 341 T+ + + +T+DDF++ +++ Sbjct: 436 TIDAEVMNSLAVTMDDFRWGLSQ 458 >pir||T02901 MSP1 protein homolog T13J8.110 - Arabidopsis thaliana >gi|4455359|emb|CAB36769.1| (AL035524) putative protein [Arabidopsis thaliana] >gi|7269654|emb|CAB79602.1| (AL161572) putative protein [Arabidopsis thaliana] Length = 726 Score = 152 bits (381), Expect = 5e-36 Identities = 106/348 (30%), Positives = 176/348 (50%), Gaps = 59/348 (16%) Query: 42 IASENLSLSHILLEEAKKWEEKAKNVRKRREGK-----NEYFDKLKALIKRST---ITWN 93 I+S +LS +L+E + E + + + K NE+ +++ + + +T+ Sbjct: 355 ISSNSLSHGLNILQEGQGCFEDSLKLDTNIDSKEVAPDNEFEKRIRPEVIPANEIGVTFA 414 Query: 94 DIGGLREAKKLIAQAIGLSIAKSPI------EPPQGILLFGPPGTGKSLLASAVANSLNA 147 DIG L E K+ + + + L + + + +P +GILLFGPPGTGK+++A A+AN A Sbjct: 415 DIGSLDETKESLQELVMLPLRRPDLFKGGLLKPCRGILLFGPPGTGKTMMAKAIANEAGA 474 Query: 148 TFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSL--TMKRVSLDDAARR 205 +F +V S + SK+FGE K + ALF+LA ++SP++IF+DEVDS+ RV +A R+ Sbjct: 475 SFINVSMSTITSKWFGEDEKNVRALFTLAAKVSPTIIFVDEVDSMLGQRTRVGEHEAMRK 534 Query: 206 MIGTLLAEMDGFKERK-DKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKI 264 + + DG D+++VL ATN P+DLDEA++ R RI V LP V S +I + Sbjct: 535 IKNEFMTHWDGLMSNAGDRILVLAATNRPFDLDEAIIRRFERRIMVGLPSVESREKILR- 593 Query: 265 HLRGIHYDVPLSRLAKEAVKRL-----------YSGREIANVVKLATMKMLEEM------ 307 + L+KE + L YSG ++ N A + + E+ Sbjct: 594 -----------TLLSKEKTENLDFQELAQMTDGYSGSDLKNFCTTAAYRPVRELIKQECL 642 Query: 308 -------------NPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARI 342 N E + + R +T RPL+++D K A +++ Sbjct: 643 KDQERRKREEAEKNSEEGSEAKEEVSEERGITLRPLSMEDMKVAKSQV 690 >gb|AAD20084.1| (AC006836) putative AAA-type ATPase [Arabidopsis thaliana] Length = 603 Score = 152 bits (380), Expect = 6e-36 Identities = 96/285 (33%), Positives = 150/285 (51%), Gaps = 35/285 (12%) Query: 90 ITWNDIGGLREAKKLIAQAI------GLSIAKSPIEPPQGILLFGPPGTGKSLLASAVAN 143 +TW+D+GGL++ KK + QA+ + K I P +GILL GPPG K+ LA A AN Sbjct: 283 VTWDDVGGLKDLKKKLQQAVEWPIKHSAAFVKMGISPMRGILLHGPPGCSKTTLAKAAAN 342 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR-----VS 198 + A+FFS+ ++L S Y GE L+ F AR SPS+IF DE D + KR + Sbjct: 343 AAQASFFSLSCAELFSMYVGEGEALLRNTFQRARLASPSIIFFDEADVVACKRGDESSSN 402 Query: 199 LDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVN 256 R++ TLL EMDG +E K ++VL ATN P+ +D A++ R + +YVP PD+ Sbjct: 403 SSTVGERLLSTLLTEMDGLEEAKG-ILVLAATNRPYAIDAALMRPGRFDLVLYVPPPDLE 461 Query: 257 SAVEIFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDP 314 + EI ++H R + DV L ++A+E L++G E+ + + E L + Sbjct: 462 ARFEILQVHTRNMTLGDDVDLRKIAEET--DLFTGAELEGLCR-------ESGTVSLREN 512 Query: 315 LRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAK 359 + + + R F+ A + +K +T +V+ Y + K Sbjct: 513 IAATAVFNR----------HFQTAKSSLKPALTIEEVETYSSFRK 547 Score = 75.3 bits (182), Expect = 1e-12 Identities = 61/233 (26%), Positives = 108/233 (46%), Gaps = 16/233 (6%) Query: 94 DIGGLREAKKLIAQAIGLSIAKSPIEP-------PQGILLFGPPGTGKSLLASAVANSLN 146 +IGG A + + + I + P+E P+G+LL+GPPGTGK+ L AV + Sbjct: 23 EIGGNERALQALRELIIFPF-RYPLEARTLGLKWPRGLLLYGPPGTGKTSLVRAVVQECD 81 Query: 147 ATFFSVKASDLLSKYFGESSKLISALFSLARQLS----PSVIFIDEVDSLTMKRVSLDDA 202 A + + + GES K++ F+ A + PSVIFIDE+D L +R + + Sbjct: 82 AHLIVLSPHSVHRAHAGESEKVLREAFAEASSHAVSDKPSVIFIDEIDVLCPRRDARREQ 141 Query: 203 ARRMIGTLLAEMDGFKERKD--KVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSA 258 R+ L MD K +V+V+ +TN +D A+ R + V P+ Sbjct: 142 DVRIASQLFTLMDSNKPSSSAPRVVVVASTNRVDAIDPALRRAGRFDALVEVSTPNEEDR 201 Query: 259 VEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPEL 311 ++I +++ + ++ D + A Y G ++ + + AT+ + + L Sbjct: 202 LKILQLYTKKVNLDPSVDLQAIAISCNGYVGADLEALCREATISASKRSSDSL 254 >sp|O05209|VAT_THEAC VCP-LIKE ATPASE >gi|7484232|pir||T37458 VCP-like ATPase - Thermoplasma acidophilum >gi|1916752|gb|AAC45089.1| (U78072) VCP-like ATPase [Thermoplasma acidophilum] >gi|10640117|emb|CAC11969.1| (AL445065) VAT ATPase (VCP-like ATPase) [Thermoplasma acidophilum] Length = 745 Score = 152 bits (379), Expect = 8e-36 Identities = 94/270 (34%), Positives = 151/270 (55%), Gaps = 20/270 (7%) Query: 53 LLEEAKKWEEKAKNVRKRREGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLS 112 +LE+ E+ KN K E + + +++ + W+DIGGL + K+ I + + L Sbjct: 431 ILEKMVVTEDDFKNALKSIEPSS----LREVMVEVPNVHWDDIGGLEDVKREIKETVELP 486 Query: 113 IAKSP------IEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESS 166 + K I P +G LL+GPPG GK+LLA AVA NA F S+K ++LSK+ GES Sbjct: 487 LLKPDVFKRLGIRPSKGFLLYGPPGVGKTLLAKAVATESNANFISIKGPEVLSKWVGESE 546 Query: 167 KLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDA--ARRMIGTLLAEMDGFKERKDKV 224 K I +F A+Q++P+++F+DE+DS+ +R + D+ R++ LL +DG E + V Sbjct: 547 KAIREIFKKAKQVAPAIVFLDEIDSIAPRRGTTSDSGVTERIVNQLLTSLDGI-EVMNGV 605 Query: 225 IVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHY--DVPLSRLAK 280 +V+ ATN P +D A+L R IY+P PD + + I K+H + + DV L+ +A+ Sbjct: 606 VVIGATNRPDIMDPALLRAGRFDKLIYIPPPDKEARLSILKVHTKNMPLAPDVDLNDIAQ 665 Query: 281 EAVKRLYSGREIANVVKLATMKMLEEMNPE 310 Y G ++ N+ + A M E NP+ Sbjct: 666 RT--EGYVGADLENLCREAGMNAYRE-NPD 692 Score = 148 bits (370), Expect = 9e-35 Identities = 102/275 (37%), Positives = 149/275 (54%), Gaps = 28/275 (10%) Query: 88 STITWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFGPPGTGKSLLASA 140 S I++ DIGGL E I + I L + K P I PP+G++L+GPPGTGK+L+A A Sbjct: 185 SRISYEDIGGLSEQLGKIREMIELPL-KHPELFERLGITPPKGVILYGPPGTGKTLIARA 243 Query: 141 VANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD 200 VAN A F S+ +++SKY+G+S + + +FS A + +PS+IFIDE+DS+ KR + Sbjct: 244 VANESGANFLSINGPEIMSKYYGQSEQKLREIFSKAEETAPSIIFIDEIDSIAPKREEVQ 303 Query: 201 -DAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNS 257 + RR++ LL MDG KER VIV+ ATN +D A+ R I + +PD N Sbjct: 304 GEVERRVVAQLLTLMDGMKER-GHVIVIGATNRIDAIDPALRRPGRFDREIEIGVPDRNG 362 Query: 258 AVEIFKIHLRGIHYDVPLSRLAKEAVKRL---------YSGREIANVVKLATMKMLEEMN 308 EI IH R ++PL +E K L + G ++A +V+ + M L Sbjct: 363 RKEILMIHTR----NMPLGMSEEEKNKFLEEMADYTYGFVGADLAALVRESAMNALRRYL 418 Query: 309 PELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIK 343 PE+ + T L +T DDFK A+ I+ Sbjct: 419 PEIDLDKPIPT---EILEKMVVTEDDFKNALKSIE 450 >gi|11230794 fidgetin-like 1 [Mus musculus] >gi|10442029|gb|AAG17290.1|AF263914_1 (AF263914) fidgetin-like 1 [Mus musculus] Length = 683 Score = 152 bits (379), Expect = 8e-36 Identities = 97/285 (34%), Positives = 156/285 (54%), Gaps = 25/285 (8%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSPI-----EPPQGILLFGPPGTGKSLLASAVANS 144 + W+DI G+ AK I + + + + I PP+GILLFGPPGTGK+L+ +A+ Sbjct: 407 VHWDDIAGVEFAKATIKEIVVWPMMRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQ 466 Query: 145 LNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD-DAA 203 ATFFS+ AS L SK+ GE K++ ALF++AR P+VIFIDE+DSL +R + +++ Sbjct: 467 SGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHESS 526 Query: 204 RRMIGTLLAEMDG-FKERKDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIF 262 RR+ L ++DG +D+++V+ ATN P ++DEA RL R+Y+PLP+ ++ +I Sbjct: 527 RRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIV 586 Query: 263 KIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVSTLKG 322 + LS + V + G A++ +L L P+R +L Sbjct: 587 GNLMS--KEQCCLSDEETDLVVQQSDGFSGADMTQLCREASL--------GPIR--SLHA 634 Query: 323 RDLTT------RPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 D+ T RP+ DF+ A ++ ++ D++ YE W + F Sbjct: 635 ADIATISPDQVRPIAYIDFENAFKTVRPTVSPKDLELYENWNETF 679 >pir||T11652 probable transitional endoplasmic reticulum ATPase - fission yeast (Schizosaccharomyces pombe) (fragment) >gi|2330848|emb|CAB11085.1| (Z98533) transitional endoplasmic reticulum atpase [Schizosaccharomyces pombe] Length = 432 Score = 151 bits (378), Expect = 1e-35 Identities = 99/299 (33%), Positives = 157/299 (52%), Gaps = 23/299 (7%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKS 135 + +++ + W DIGGL E K+ + + + + + + + P +G+L FGPPGTGK+ Sbjct: 103 ETVVEVPNVRWEDIGGLEEVKRELRETVQMPVMYAEKFLRFGVTPSKGVLFFGPPGTGKT 162 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 LLA A+AN +A F SVK +LLS +FGES + +F AR +P V+F+DE+DS+ Sbjct: 163 LLAKAIANECSANFISVKGPELLSMWFGESESNVRDIFDKARAAAPCVVFLDELDSIAKA 222 Query: 196 R-VSLDDA--ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYV 250 R S D+ R++ LL EMDG +K+ V V+ ATN P +D A++ RL IYV Sbjct: 223 RGASAGDSGGGDRVVNQLLTEMDGVNSKKN-VFVIGATNRPDQIDPALMRPGRLDQLIYV 281 Query: 251 PLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGRE----IANVVKLATMKML 304 PLPD + I + LR + DV L +AK +SG + + VKLA + Sbjct: 282 PLPDEEARFSILQTQLRHTPVAEDVDLRAVAK--ATHGFSGADLEFVVQRAVKLAIKDSI 339 Query: 305 EE---MNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKE 360 EE E + + D + + + AM + ++ ++V++YE +A + Sbjct: 340 EEDIKRENETGEAPADDVVMDEDASVSQVQRHHVEEAMKMARRSVSDAEVRRYEAYAHQ 398 >gi|10946660 spermatogenesis associated factor [Mus musculus] >gi|4105619|gb|AAD02481.1| (AF049099) SPAF [Mus musculus] Length = 892 Score = 150 bits (376), Expect = 2e-35 Identities = 91/230 (39%), Positives = 135/230 (58%), Gaps = 16/230 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGL------SIAKSPIEPPQGILLFGPPGTGKSLLASAVAN 143 ++W+DIGGL K + QA+ S + I+PP+G+LL+GPPG K+++A A+AN Sbjct: 623 VSWSDIGGLENIKLKLKQAVEWPLKHPKSFNRMGIQPPKGVLLYGPPGCSKTMIAKALAN 682 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDA- 202 F ++K +L++KY GES + + +F AR ++PS+IF DE+D+L ++R S A Sbjct: 683 ESGLNFLAIKGPELMNKYVGESERAVREIFRKARAVAPSIIFFDELDALAVERGSSSGAG 742 Query: 203 --ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSA 258 A R++ LL EMDG ++ K+ V VL ATN P +D+A++ R+ IYVPLPD + Sbjct: 743 NVADRVLAQLLTEMDGIEQLKN-VTVLAATNRPDRIDKALMRPGRIDRIIYVPLPDAATR 801 Query: 259 VEIFKI--HLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEE 306 EI + H I +V L L + YSG EI V K A + LEE Sbjct: 802 REILNLQFHSMPISNEVDLDELVLQT--DTYSGAEIIAVCKEAALLALEE 849 Score = 115 bits (286), Expect = 6e-25 Identities = 87/272 (31%), Positives = 140/272 (50%), Gaps = 29/272 (10%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFGPPGTGKSLLASAVA 142 +T++ IGGL K I + I L + K P I P+G+LL+GPPGTGK+++A AVA Sbjct: 349 VTYDMIGGLNSQLKAIREIIELPL-KQPELFKSYGIPAPRGLLLYGPPGTGKTMIARAVA 407 Query: 143 NSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRV-SLDD 201 N + A + +++SK++GE+ + +F+ A PS+IFIDE+D+L KR + + Sbjct: 408 NEVGAYVSVINGPEIISKFYGETEARLRQIFAEATLRHPSIIFIDELDALCPKREGAQSE 467 Query: 202 AARRMIGTLLAEMDGF--KERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNS 257 +R++ +LL MDG + + +V+VL ATN P LD A+ R I + +P+ Sbjct: 468 VEKRVVASLLTLMDGIGSEGSEGRVLVLGATNRPQALDAALRRPGRFDKEIEIGIPNAQD 527 Query: 258 AVEIFKIHLRGIHY---DVPLSRLAKEAVKRLYSG---REIANVVKLATMKMLEEMNPEL 311 ++I + LR + + L RLA A Y G + + N L ++ + P L Sbjct: 528 RLDILQKLLRRVPHLLTKAELLRLANNA--HGYVGADLKALCNEAGLHALRRVLRKQPNL 585 Query: 312 SDPLRVSTLKGRDLTTRPLTLDDFKYAMARIK 343 D +K +TL+DF M I+ Sbjct: 586 PDSKVAGMVK--------ITLNDFLQGMNDIR 609 >gb|AAK40609.1| AAA family ATPase [Sulfolobus solfataricus] Length = 393 Score = 150 bits (375), Expect = 2e-35 Identities = 92/249 (36%), Positives = 145/249 (57%), Gaps = 16/249 (6%) Query: 74 KNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILL 126 K + K +I+R +T+++IGGL E + + + + L + K+P +EPP+G+LL Sbjct: 115 KEDPIVKTMEIIERPNVTYSEIGGLEEQIRELREVVELPL-KNPEIFREIGVEPPKGVLL 173 Query: 127 FGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFI 186 +GPPGTGK++LA AVA NA F V AS+ K+ GE ++++ LF +A++ +PS+IFI Sbjct: 174 YGPPGTGKTMLAKAVATESNAVFIHVVASEFAQKFVGEGARIVRELFEMAKRKAPSIIFI 233 Query: 187 DEVDSLTMKRVSLDDAARRMIG----TLLAEMDGFKERKDKVIVLTATNAPWDLDEAML- 241 DE+D++ KR+ + + R I LLAE+DGF + D V ++ ATN LD A+L Sbjct: 234 DEIDAIGAKRIDIGTSGEREIQRTLMQLLAELDGF-DPLDNVKIIAATNRIDILDPALLR 292 Query: 242 -SRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANV-VKLA 299 R I VPLPD EIF I+L+ + + ++ + +SG +I NV V+ A Sbjct: 293 PGRFDRIIEVPLPDFKGRTEIFNIYLKKMKIEDNINLELLSQLTEGFSGADIKNVCVEAA 352 Query: 300 TMKMLEEMN 308 M + + N Sbjct: 353 YMAIRDGRN 361 >sp|P34808|MEI1_CAEEL MEIOTIC SPINDLE FORMATION PROTEIN MEI-1 >gi|7506899|pir||T24316 hypothetical protein T01G9.5 - Caenorhabditis elegans >gi|409131|gb|AAA28109.1| (L25423) mei-1 [Caenorhabditis elegans] >gi|3879272|emb|CAB00052.1| (Z75713) contains similarity to Pfam domain: PF00004 (ATPases associated with various cellular activities (AAA)), Score=287.9, E-value=4.2e-83, N=1~cDNA EST EMBL:M88967 comes from this gene~cDNA EST yk257a12.3 comes from this gene~cDNA EST yk257a12.5 c> Length = 472 Score = 150 bits (374), Expect = 3e-35 Identities = 90/290 (31%), Positives = 162/290 (55%), Gaps = 24/290 (8%) Query: 88 STITWNDIGGLREAKKLIAQAIGLSIAKSPI-----EPPQGILLFGPPGTGKSLLASAVA 142 +T++ +DI G+ + K+++ +A+ L + P + ++L GPPGTGK+L+A A+A Sbjct: 188 NTMSLDDIIGMHDVKQVLHEAVTLPLLVPEFFQGLRSPWKAMVLAGPPGTGKTLIARAIA 247 Query: 143 NSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL--D 200 + ++TFF+V ++DL SK+ G+S K++ LF LAR +PS+IFIDE+D+L +R + Sbjct: 248 SESSSTFFTVSSTDLSSKWRGDSEKIVRLLFELARFYAPSIIFIDEIDTLGGQRGNSGEH 307 Query: 201 DAARRMIGTLLAEMDGFKERKD--KVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSA 258 +A+RR+ L +MDG + + D +V VL ATN PW+LDEA+ R RI++PLPD+++ Sbjct: 308 EASRRVKSEFLVQMDGSQNKFDSRRVFVLAATNIPWELDEALRRRFEKRIFIPLPDIDAR 367 Query: 259 VEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 ++ + + G ++ A +SG ++ ++ + A + +L + Sbjct: 368 KKLIEKSMEGTPKSDEINYDDLAARTEGFSGADVVSLCRTAAINVLRRYD--------TK 419 Query: 319 TLKGRDLTTRPLTLD-------DFKYAMARIKSPITKSDVKKYERWAKEF 361 +L+G +LT +L DF+ A+ + + K + W F Sbjct: 420 SLRGGELTAAMESLKAELVRNIDFEAALQAVSPSAGPDTMLKCKEWCDSF 469 >sp|P54609|CC48_ARATH CELL DIVISION CYCLE PROTEIN 48 HOMOLOG >gi|2118115|pir||S60112 transitional endoplasmic reticulum ATPase - Arabidopsis thaliana >gi|1019904|gb|AAC49120.1| (U37587) cell division cycle protein [Arabidopsis thaliana] >gi|6681343|gb|AAF23260.1|AC015985_18 (AC015985) putative transitional endoplasmic reticulum ATPase [Arabidopsis thaliana] Length = 809 Score = 150 bits (374), Expect = 3e-35 Identities = 100/306 (32%), Positives = 158/306 (50%), Gaps = 38/306 (12%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKS 135 + +++ ++WNDIGGL K+ + + + + K + P +G+L +GPPG GK+ Sbjct: 469 ETVVEVPNVSWNDIGGLENVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKT 528 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 LLA A+AN A F SVK +LL+ +FGES + +F ARQ +P V+F DE+DS+ + Sbjct: 529 LLAKAIANECQANFISVKGPELLTMWFGESEANVREIFDKARQSAPCVLFFDELDSIATQ 588 Query: 196 RVSLD-----DAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRI 248 R AA R++ LL EMDG +K V ++ ATN P +D A+L RL I Sbjct: 589 RGGGSGGDGGGAADRVLNQLLTEMDGMNAKK-TVFIIGATNRPDIIDSALLRPGRLDQLI 647 Query: 249 YVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEE 306 Y+PLPD +S + IFK LR I DV + LAK + +SG +I + + A + E Sbjct: 648 YIPLPDEDSRLNIFKAALRKSPIAKDVDIGALAK--YTQGFSGADITEICQRACKYAIRE 705 Query: 307 -------------MNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKK 353 NPE + V + + F+ +M + ++ +D++K Sbjct: 706 NIEKDIEKEKRRSENPEAMEEDGVDEVS-------EIKAAHFEESMKYARRSVSDADIRK 758 Query: 354 YERWAK 359 Y+ +A+ Sbjct: 759 YQAFAQ 764 Score = 133 bits (331), Expect = 3e-30 Identities = 80/228 (35%), Positives = 129/228 (56%), Gaps = 14/228 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 + ++D+GG+R+ I + + L + ++PP+GILL+GPPG+GK+L+A AVAN Sbjct: 204 VGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVAN 263 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD-DA 202 A FF + +++SK GES + F A + +PS+IFIDE+DS+ KR + + Sbjct: 264 ETGAFFFCINGPEIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTNGEV 323 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSAVE 260 RR++ LL MDG K R VIV+ ATN P +D A+ R I + +PD +E Sbjct: 324 ERRIVSQLLTLMDGLKSRA-HVIVMGATNRPNSIDPALRRFGRFDREIDIGVPDEIGRLE 382 Query: 261 IFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEE 306 + +IH + + DV L R++K+ Y G ++A + A ++ + E Sbjct: 383 VLRIHTKNMKLAEDVDLERISKDT--HGYVGADLAALCTEAALQCIRE 428 >pir||T48355 transitional endoplasmic reticulum ATPase - Arabidopsis thaliana >gi|7378614|emb|CAB83290.1| (AL162751) transitional endoplasmic reticulum ATPase [Arabidopsis thaliana] Length = 843 Score = 150 bits (374), Expect = 3e-35 Identities = 99/305 (32%), Positives = 159/305 (51%), Gaps = 36/305 (11%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKS 135 + +++ ++W DIGGL K+ + + + + K + P +G+L +GPPG GK+ Sbjct: 502 ETVVEVPNVSWEDIGGLENVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKT 561 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 LLA A+AN A F SVK +LL+ +FGES + +F ARQ +P V+F DE+DS+ + Sbjct: 562 LLAKAIANECQANFISVKGPELLTMWFGESEANVREIFDKARQSAPCVLFFDELDSIATQ 621 Query: 196 RVS----LDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIY 249 R + AA R++ LL EMDG +K V ++ ATN P +D A+L RL IY Sbjct: 622 RGNSAGDAGGAADRVLNQLLTEMDGMNAKK-TVFIIGATNRPDIIDSALLRPGRLDQLIY 680 Query: 250 VPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEE- 306 +PLPD +S + IFK LR + DV ++ LAK + +SG +I + + A + E Sbjct: 681 IPLPDEDSRLNIFKACLRKSPVAKDVDVTALAK--YTQGFSGADITEICQRACKYAIREN 738 Query: 307 ------------MNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKY 354 NPE + V D + F+ +M + ++ +D++KY Sbjct: 739 IEKDIENERRRSQNPEAMEEDMV------DDEVSEIRAAHFEESMKYARRSVSDADIRKY 792 Query: 355 ERWAK 359 + +A+ Sbjct: 793 QAFAQ 797 Score = 133 bits (331), Expect = 3e-30 Identities = 80/228 (35%), Positives = 129/228 (56%), Gaps = 14/228 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 + ++D+GG+R+ I + + L + ++PP+GILL+GPPG+GK+L+A AVAN Sbjct: 237 VGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVAN 296 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD-DA 202 A FF + +++SK GES + F A + +PS+IFIDE+DS+ KR + + Sbjct: 297 ETGAFFFCINGPEIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTNGEV 356 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSAVE 260 RR++ LL MDG K R VIV+ ATN P +D A+ R I + +PD +E Sbjct: 357 ERRIVSQLLTLMDGLKSRA-HVIVMGATNRPNSIDPALRRFGRFDREIDIGVPDEIGRLE 415 Query: 261 IFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEE 306 + +IH + + DV L R++K+ Y G ++A + A ++ + E Sbjct: 416 VLRIHTKNMKLAEDVDLERISKDT--HGYVGADLAALCTEAALQCIRE 461 >sp|O26824|PRS1_METTH PUTATIVE 26S PROTEASE REGULATORY SUBUNIT HOMOLOG MTH728 >gi|7435737|pir||C69197 ATP-dependent 26S proteinase regulatory subunit 4 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621817|gb|AAB85233.1| (AE000852) ATP-dependent 26S protease regulatory subunit 4 [Methanobacterium thermoautotrophicum] Length = 410 Score = 149 bits (373), Expect = 4e-35 Identities = 84/196 (42%), Positives = 123/196 (61%), Gaps = 13/196 (6%) Query: 86 KRSTITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLAS 139 ++ +++ IGGL E + + + + L + K IEPP+G+LL+GPPGTGK+LLA Sbjct: 144 EKPDVSYEQIGGLEEQVREVKETVELPLKKPELFEKIGIEPPKGVLLYGPPGTGKTLLAK 203 Query: 140 AVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRV-- 197 AVA+ NATF + AS+ + KY GE ++L+ +F LA++ SPS+IFIDE+D++ KR+ Sbjct: 204 AVAHETNATFIKIVASEFVRKYIGEGARLVRGVFELAKEKSPSIIFIDEIDAVAAKRLKS 263 Query: 198 --SLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLP 253 S D +R + LLAE+DGF E + V ++ ATN P LD A+L R I VPLP Sbjct: 264 STSGDREVQRTLMQLLAELDGF-ESRGNVGIVAATNRPDILDPALLRPGRFDRFIEVPLP 322 Query: 254 DVNSAVEIFKIHLRGI 269 + + EI KIH G+ Sbjct: 323 NEDGRREILKIHTSGM 338 >sp|P54774|CC48_SOYBN CELL DIVISION CYCLE PROTEIN 48 HOMOLOG (VALOSIN CONTAINING PROTEIN HOMOLOG) (VCP) >gi|7435757|pir||T06409 valosin-containing protein - soybean >gi|862480|gb|AAA80587.1| (U20213) valosin-containing protein [Glycine max] Length = 807 Score = 148 bits (371), Expect = 7e-35 Identities = 101/305 (33%), Positives = 158/305 (51%), Gaps = 36/305 (11%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKS 135 + +++ ++W DIGGL K+ + + + + K + P +G+L +GPPG GK+ Sbjct: 470 ETVVEVPNVSWEDIGGLENVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKT 529 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 LLA A+AN A F SVK +LL+ +FGES + +F ARQ +P V+F DE+DS+ + Sbjct: 530 LLAKAIANECQANFISVKGPELLTMWFGESEANVREIFDKARQSAPCVLFFDELDSIATQ 589 Query: 196 RVS----LDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIY 249 R S AA R++ LL EMDG +K V ++ ATN P +D A+L RL IY Sbjct: 590 RGSSVGDAGGAADRVLNQLLTEMDGMSAKK-TVFIIGATNRPDIIDPALLRPGRLDQLIY 648 Query: 250 VPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEE- 306 +PLPD +S +IFK LR I +V L LA+ + +SG +I + + A + E Sbjct: 649 IPLPDEDSRHQIFKACLRKSPIAKNVDLRALARHT--QGFSGADITEICQRACKYAIREN 706 Query: 307 ------------MNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKY 354 NPE D V D + F+ +M + ++ +D++KY Sbjct: 707 IEKDIERERKSRENPEAMDEDTV------DDEVAEIKAAHFEESMKFARRSVSDADIRKY 760 Query: 355 ERWAK 359 + +A+ Sbjct: 761 QAFAQ 765 Score = 135 bits (337), Expect = 7e-31 Identities = 87/261 (33%), Positives = 141/261 (53%), Gaps = 16/261 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 + ++D+GG+R+ I + + L + ++PP+GILL+GPPG+GK+L+A AVAN Sbjct: 205 VGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVAN 264 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL-DDA 202 A FF + +++SK GES + F A + +PS+IFIDE+DS+ KR + Sbjct: 265 ETGAFFFCINGPEIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEV 324 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSAVE 260 RR++ LL MDG K R VIV+ ATN P +D A+ R I + +PD +E Sbjct: 325 ERRIVSQLLTLMDGLKSRA-HVIVIGATNRPNSIDPALRRFGRFDREIDIGVPDEVGRLE 383 Query: 261 IFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 + +IH + + DV L R+AK+ Y G ++A + A ++ + E + L Sbjct: 384 VLRIHTKNMKLSDDVDLERIAKDT--HGYVGADLAALCTEAALQCIREKMDVID--LEDE 439 Query: 319 TLKGRDLTTRPLTLDDFKYAM 339 T+ L + +T + F+ A+ Sbjct: 440 TIDAEVLNSMAVTNEHFQTAL 460 >sp|P54811|TER1_CAEEL TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE HOMOLOG 1 (P97/CDC48 HOMOLOG 1) >gi|7495467|pir||T18970 hypothetical protein C06A1.1 - Caenorhabditis elegans >gi|3874005|emb|CAA90050.1| (Z49886) contains similarity to Pfam domain: PF00004 (ATPases associated with various cellular activities (AAA)), Score=658.1, E-value=1.5e-194, N=2~cDNA EST yk76f10.5 comes from this gene; cDNA EST yk3h5.5 comes from this gene~cDNA EST yk6d7.5 comes f> Length = 809 Score = 148 bits (371), Expect = 7e-35 Identities = 104/313 (33%), Positives = 165/313 (52%), Gaps = 28/313 (8%) Query: 72 EGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGIL 125 +GK+ +A+++ TW+DIGGL+ K+ + + + + K ++P +G+L Sbjct: 462 QGKSSPSALREAVVETPNTTWSDIGGLQNVKRELQELVQYPVEHPEKYLKFGMQPSRGVL 521 Query: 126 LFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIF 185 +GPPG GK+LLA A+AN A F S+K +LL+ +FGES + +F AR +P V+F Sbjct: 522 FYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDVFDKARAAAPCVLF 581 Query: 186 IDEVDSLTMKR-----VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM 240 DE+DS+ R A+ R+I +L EMDG +K+ V ++ ATN P +D A+ Sbjct: 582 FDELDSIAKARGGGAGGDGGGASDRVINQVLTEMDGMNAKKN-VFIIGATNRPDIIDPAV 640 Query: 241 L--SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANV- 295 L RL IY+PLPD S +I K LR + D+ L+ LAK V +SG ++ + Sbjct: 641 LRPGRLDQLIYIPLPDEASRHQILKASLRKTPLSKDLDLTFLAKNTVG--FSGADLTEIC 698 Query: 296 ---VKLATMKMLEE---MNPELSDPLRVSTLKGRDLTTRP---LTLDDFKYAMARIKSPI 346 KLA + +E+ + E D D P +T F+ AM + + Sbjct: 699 QRACKLAIRESIEKEIRIEKERQDRQARGEELMEDDAVDPVPEITRAHFEEAMKFARRSV 758 Query: 347 TKSDVKKYERWAK 359 T +D++KYE +A+ Sbjct: 759 TDNDIRKYEMFAQ 771 Score = 134 bits (334), Expect = 1e-30 Identities = 85/263 (32%), Positives = 145/263 (54%), Gaps = 16/263 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 I ++D+GG+R+ I + + L + I+PP+GILLFGPPGTGK+L+A AVAN Sbjct: 207 IGYDDLGGVRKQLAQIKEMVELPLRHPQLFKAIGIKPPRGILLFGPPGTGKTLIARAVAN 266 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD-DA 202 + FF + +++SK GES + F + P+++FIDE+D++ KR + + Sbjct: 267 ETGSFFFLINGPEVMSKMSGESESNLRKAFEECEKNQPAILFIDEIDAIAPKREKTNGEV 326 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSAVE 260 RR++ LL MDG K R + ++V+ ATN P +D A+ R I + +PD +E Sbjct: 327 ERRIVSQLLTLMDGVKGRSN-LVVIAATNRPNSIDGALRRFGRFDREIDIGIPDAVGRLE 385 Query: 261 IFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 I +IH + + DV L ++A E + G ++A++ A ++ + E EL D L Sbjct: 386 ILRIHTKNMKLADDVDLEQIANEC--HGFVGADLASLCSEAALQQIRE-KMELID-LEDD 441 Query: 319 TLKGRDLTTRPLTLDDFKYAMAR 341 + L + +T+++F++A + Sbjct: 442 QIDAEVLNSLAVTMENFRFAQGK 464 >pir||A69086 cell division control protein Cdc48 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622767|gb|AAB86112.1| (AE000923) cell division control protein Cdc48 [Methanobacterium thermoautotrophicum] Length = 732 Score = 148 bits (371), Expect = 7e-35 Identities = 104/277 (37%), Positives = 152/277 (54%), Gaps = 26/277 (9%) Query: 53 LLEEAKKWEEKAKNVRKRRE-GKNEYFDKLK---------ALIKRSTITWNDIGGLREAK 102 +L E K EE K V K+ + ++ D LK L++ ++W+DIGGL AK Sbjct: 427 VLPEIKADEEIPKEVLKKMVVTRADFKDALKEIQPSALREVLVQVPNVSWDDIGGLEGAK 486 Query: 103 KLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASD 156 + + +A+ + K I PP+GILL G PGTGK+LLA AVAN A F +VK + Sbjct: 487 QELREAVEWPLKYPDRFKKFGIRPPKGILLHGSPGTGKTLLAKAVANESQANFIAVKGPE 546 Query: 157 LLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR---VSLDDAARRMIGTLLAE 213 LLSK+ GES K + +F ARQ +P+VIF DE+DS+ R + +R++ LL E Sbjct: 547 LLSKWVGESEKGVREVFRKARQTAPTVIFFDEIDSIASVRSGSTADSGVTQRVVNQLLTE 606 Query: 214 MDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHY 271 +DG +E +D V V+ ATN P LD A+L R + V PD + + IF++H + + Sbjct: 607 IDGLEELQD-VAVIAATNRPDILDPALLRPGRFDRHVKVEDPDKEARLAIFRVHTKDMPL 665 Query: 272 --DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEE 306 DV L +LA++ Y G +I V + A M L + Sbjct: 666 ADDVDLEKLAEKT--EGYVGADIEAVCREAAMLTLRD 700 Score = 147 bits (368), Expect = 2e-34 Identities = 95/275 (34%), Positives = 151/275 (54%), Gaps = 17/275 (6%) Query: 80 KLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTG 133 KL+ + +T+ DIGGL+E K + + I + + + I PP+G+L+ GPPGTG Sbjct: 192 KLEGVKNLVDVTYEDIGGLKEEVKKVREMIEIPLKRPELFERLGITPPKGVLMHGPPGTG 251 Query: 134 KSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLT 193 K+LLA AVAN +A F ++ +++SKY G S + + F A + +PS+IFIDE+D++ Sbjct: 252 KTLLAKAVANESDAHFIAINGPEIMSKYVGGSEERLREFFEEAEENAPSIIFIDEIDAIA 311 Query: 194 MKRVSLD-DAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYV 250 KR + + RR++ LL MDG K R +V+V+ ATN P LD A+ R I + Sbjct: 312 PKREDVSGEVERRIVAQLLTLMDGLKSR-GQVVVIGATNRPDALDPALRRPGRFDREIEI 370 Query: 251 PLPDVNSAVEIFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMN 308 +PD EI +IH RG+ DV L LA+ + + G ++ ++ K + M++L + Sbjct: 371 GVPDREERKEILQIHTRGMPLADDVDLDELAE--ITHGFVGADLESLCKESAMRVLRRVL 428 Query: 309 PELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIK 343 PE+ + L +T DFK A+ I+ Sbjct: 429 PEIKAD---EEIPKEVLKKMVVTRADFKDALKEIQ 460 >gb|AAC27447.1| (AF047037) transitional endoplasmic reticulum ATPase TER94 [Drosophila melanogaster] Length = 801 Score = 148 bits (371), Expect = 7e-35 Identities = 116/372 (31%), Positives = 181/372 (48%), Gaps = 32/372 (8%) Query: 15 EFERALSLGHYDKARLIALRCAELLRKIASENLSLSHILLEEAKKWEEKAKNVRKRREGK 74 + E+ + H +A C+E + E + L I LE+ K E ++ E Sbjct: 392 DLEQIAAESHGHVGADLASLCSEAALQQIREKMDL--IDLEDDKIDAEVLASLAVTMENF 449 Query: 75 NEYFDKLKALIKRSTI------TWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQ 122 K R T+ TW DIGGL KK + + + + K ++P + Sbjct: 450 RYAMTKSSPSALRETVVEVPNTTWTDIGGLESVKKELQELVQYPVEHPDKFLKFGMQPSR 509 Query: 123 GILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPS 182 G+L +GPPG GK+LLA A+AN A F SVK +LL+ +FGES + +F AR +P Sbjct: 510 GVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDKARSAAPC 569 Query: 183 VIFIDEVDSLTMKR----VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDE 238 V+F DE+DS+ R AA R+I +L EMDG +K+ V ++ ATN P +D Sbjct: 570 VLFFDELDSIAKARGGNVGDAGGAADRVINQILTEMDGMGAKKN-VFIIGATNRPDIIDP 628 Query: 239 AML--SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIAN 294 A+L RL IY+PLPD S I K +LR + +V L+ +AK V + +SG ++ Sbjct: 629 AILRPGRLDQLIYIPLPDDKSREAILKANLRKSALAKEVDLTYIAK--VTQGFSGADLTE 686 Query: 295 V----VKLATMKMLE---EMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPIT 347 + KLA + +E E ++ + D +T F+ AM + ++ Sbjct: 687 ICQRACKLAIRQAIEAEIRREKERAENQNSAMDMDEDDPVPEITSAHFQEAMKFARRSVS 746 Query: 348 KSDVKKYERWAK 359 +D++KYE +A+ Sbjct: 747 DNDIRKYEMFAQ 758 Score = 142 bits (354), Expect = 7e-33 Identities = 87/265 (32%), Positives = 149/265 (55%), Gaps = 16/265 (6%) Query: 88 STITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAV 141 + + ++DIGG R+ I + + L + ++PP+GIL++GPPGTGK+L+A AV Sbjct: 196 NAVGYDDIGGCRKQLAQIKEMVELPLRHPSLFKAIGVKPPRGILMYGPPGTGKTLIARAV 255 Query: 142 ANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR-VSLD 200 AN A FF + +++SK GES + F A + SP++IFIDE+D++ KR + Sbjct: 256 ANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNSPAIIFIDEIDAIAPKRDKTHG 315 Query: 201 DAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSA 258 + RR++ LL MDG K + +IV+ ATN P +D A+ R I + +PD Sbjct: 316 EVERRIVSQLLTLMDGMK-KSSHLIVMAATNRPNSIDPALRRFGRFDREIDIGIPDATGR 374 Query: 259 VEIFKIHLRG--IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLR 316 +E+ +IH + +H DV L ++A E+ + G ++A++ A ++ + E +L D L Sbjct: 375 LEVLRIHTKNMKLHDDVDLEQIAAES--HGHVGADLASLCSEAALQQIRE-KMDLID-LE 430 Query: 317 VSTLKGRDLTTRPLTLDDFKYAMAR 341 + L + +T+++F+YAM + Sbjct: 431 DDKIDAEVLASLAVTMENFRYAMTK 455 >gi|6322994 Yll034cp [Saccharomyces cerevisiae] >gi|2492526|sp|Q07844|YL34_YEAST HYPOTHETICAL 93.1 KD PROTEIN YLL034C >gi|2131732|pir||S64785 hypothetical protein YLL034c - yeast (Saccharomyces cerevisiae) >gi|1360222|emb|CAA97483.1| (Z73139) ORF YLL034c [Saccharomyces cerevisiae] Length = 837 Score = 148 bits (370), Expect = 9e-35 Identities = 99/300 (33%), Positives = 160/300 (53%), Gaps = 30/300 (10%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKSLLASAVAN 143 +TW ++G L+ + + AI I K I P G+LL+GPPG GK+LLA AVAN Sbjct: 530 VTWANVGALQRVRLELNMAIVQPIKRPELYEKVGISAPGGVLLWGPPGCGKTLLAKAVAN 589 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR-VSLDDA 202 A F S+K +LL+KY GES + I +F+ AR P VIF DE+D+L +R SL ++ Sbjct: 590 ESRANFISIKGPELLNKYVGESERSIRQVFTRARASVPCVIFFDELDALVPRRDTSLSES 649 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVE 260 + R++ TLL E+DG +R+ + V+ ATN P +D AML RL +++ LP+ ++ Sbjct: 650 SSRVVNTLLTELDGLNDRRG-IFVIGATNRPDMIDPAMLRPGRLDKSLFIELPNTEEKLD 708 Query: 261 IFKI----HLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKML-------EEMNP 309 I K H + DV + + +SG ++A +V+ +++ L EE+ Sbjct: 709 IIKTLTKSHGTPLSSDVDFEEIIRNEKCNNFSGADLAALVRESSVLALKRKFFQSEEIQS 768 Query: 310 ELSDPLRVS------TLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEFAI 363 L + L + G ++ +T+ DF+ A+ +IK ++ D KY+R K+ + Sbjct: 769 VLDNDLDKEFEDLSVGVSGEEII---VTMSDFRSALRKIKPSVSDKDRLKYDRLNKKMGL 825 Score = 110 bits (272), Expect = 3e-23 Identities = 82/254 (32%), Positives = 131/254 (51%), Gaps = 17/254 (6%) Query: 44 SENLSLSHILLE-EAKKWEEKAKNVRKRREGKNEYF-DKLKALIKRSTITWNDIGGLREA 101 S++ S+S + E + K EE K+ ++ +EG + K+K + +GG+ + Sbjct: 154 SKSGSVSESITETDDPKTEEVKKSKKRSKEGTCKVKRQKIKEDRSPPNSSLKSLGGMDDV 213 Query: 102 KKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKAS 155 + + IGL I + +EPP+G+LL GPPG GK+ +A+A+A L F S+ A Sbjct: 214 VAQLMELIGLPILHPEIFLSTGVEPPRGVLLHGPPGCGKTSIANALAGELQVPFISISAP 273 Query: 156 DLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR--VSLDDAARRMIGTLLAE 213 ++S GES K I LF AR L+P ++F DE+D++T KR + + RR++ LL Sbjct: 274 SVVSGMSGESEKKIRDLFDEARSLAPCLVFFDEIDAITPKRDGGAQREMERRIVAQLLTS 333 Query: 214 MDGFKERKDK---VIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSAVEIFKIHLRG 268 MD K VI++ ATN P LD A+ R I + +P+ S + I K Sbjct: 334 MDELTMEKTNGKPVIIIGATNRPDSLDAALRRAGRFDREICLNVPNEVSRLHILKKMSDN 393 Query: 269 IHYD--VPLSRLAK 280 + D + ++LAK Sbjct: 394 LKIDGAIDFAKLAK 407 >sp|Q96372|CC48_CAPAN CELL DIVISION CYCLE PROTEIN 48 HOMOLOG >gi|1669660|emb|CAA70565.1| (Y09396) protein of AAA family [Capsicum annuum] Length = 805 Score = 148 bits (370), Expect = 9e-35 Identities = 101/311 (32%), Positives = 161/311 (51%), Gaps = 50/311 (16%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPIEPPQ-----------GILLFGPP 130 + +++ ++W DIGGL K+ + + + + P+EPP+ G+L +GPP Sbjct: 470 ETVVEVPNVSWEDIGGLENVKRELQETV-----QYPVEPPEKFEKFGMSPSKGVLFYGPP 524 Query: 131 GTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVD 190 G GK+LLA A+AN A F SVK +LL+ +FGES + +F ARQ +P V+F DE+D Sbjct: 525 GCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVREIFDKARQSAPCVLFFDELD 584 Query: 191 SLTMKRVS----LDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRL 244 S+ +R S AA R++ LL EMDG +K V ++ ATN P +D A+L RL Sbjct: 585 SIATQRGSSSGDAGGAADRVLNQLLTEMDGMNAKK-TVFIIGATNRPDIIDPALLRPGRL 643 Query: 245 PIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMK 302 IY+PLPD +S +IFK LR + D+ L LAK + +SG ++ + + A Sbjct: 644 DQLIYIPLPDEDSRHQIFKACLRKSPLSKDIDLRALAKHT--QGFSGADVTEICQRACKY 701 Query: 303 MLEE-------------MNPELSDPLRVSTLKGRDLTTRP-LTLDDFKYAMARIKSPITK 348 + E NP+ D D+ P + F+ +M + ++ Sbjct: 702 AIRENIEKDIEREKRRQENPDSMD---------EDVDEVPEIKPAHFEESMKYARRSVSD 752 Query: 349 SDVKKYERWAK 359 +D++KY+ +A+ Sbjct: 753 ADIRKYQAFAQ 763 Score = 132 bits (328), Expect = 8e-30 Identities = 86/261 (32%), Positives = 140/261 (52%), Gaps = 16/261 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 + ++D+GG+R+ I + + L + ++PP+GILL+GPPG+GK+L+A AVAN Sbjct: 205 VGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVAN 264 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL-DDA 202 A FF + +++SK GES + F A + +PS+IFIDE+DS+ KR + Sbjct: 265 ETGAFFFCINGPEIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEV 324 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSAVE 260 RR++ LL MDG K R VIV+ ATN P +D A+ R I + +PD +E Sbjct: 325 ERRIVSQLLTLMDGLKSRA-HVIVMGATNRPNSIDPALRRFGRFDREIDIGVPDEVGRLE 383 Query: 261 IFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 + IH + + +V L R++K+ Y G ++A + A ++ + E L L Sbjct: 384 VLGIHTKNMKLAEEVDLERISKDT--HGYVGADLAALCTEAALQCIREKMDVLD--LEDD 439 Query: 319 TLKGRDLTTRPLTLDDFKYAM 339 T+ L + +T + F+ A+ Sbjct: 440 TIDAEVLNSMAVTNEHFQTAL 460 >dbj|BAB14567.1| (AK023411) unnamed protein product [Homo sapiens] Length = 254 Score = 148 bits (370), Expect = 9e-35 Identities = 89/252 (35%), Positives = 147/252 (58%), Gaps = 24/252 (9%) Query: 120 PPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQL 179 PP+GILLFGPPGTGK+L+ +A+ ATFFS+ AS L SK+ GE K++ ALF++AR Sbjct: 13 PPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQ 72 Query: 180 SPSVIFIDEVDSLTMKRVSLD-DAARRMIGTLLAEMDG-FKERKDKVIVLTATNAPWDLD 237 P+VIFIDE+DSL +R + +++RR+ L ++DG +D+++V+ ATN P ++D Sbjct: 73 QPAVIFIDEIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEID 132 Query: 238 EAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKR--LYSGREIANV 295 EA RL R+Y+PLP+ ++ +I I+L ++ V++ +SG ++ + Sbjct: 133 EAARRRLVKRLYIPLPEASARKQIV-INLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQL 191 Query: 296 VKLATMKMLEEMNPELSDPLRVSTLKGRDLTT------RPLTLDDFKYAMARIKSPITKS 349 + A++ P+R +L+ D+ T RP+ DF+ A ++ ++ Sbjct: 192 CREASL-----------GPIR--SLQTADIATITPDQVRPIAYIDFENAFRTVRPSVSPK 238 Query: 350 DVKKYERWAKEF 361 D++ YE W K F Sbjct: 239 DLELYENWNKTF 250 >pir||S47861 mei-1 protein - Caenorhabditis elegans Length = 475 Score = 148 bits (369), Expect = 1e-34 Identities = 92/292 (31%), Positives = 162/292 (54%), Gaps = 25/292 (8%) Query: 88 STITWNDIGGLREAKKLIAQAIGLSIAKSPI-----EPPQGILLFGPPGTGKSLLASAVA 142 +T++ +DI G+ + K+++ +A+ L + P + ++L GPPGTGK+L+A A+A Sbjct: 188 NTMSLDDIIGMHDVKQVLHEAVTLPLLVPEFFQGLRSPWKAMVLAGPPGTGKTLIARAIA 247 Query: 143 NSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL--D 200 + ++TFF+V ++DL SK+ G+S K++ LF LAR +PS+IFIDE+D+L +R + Sbjct: 248 SESSSTFFTVSSTDLSSKWRGDSEKIVRLLFELARFYAPSIIFIDEIDTLGGQRGNSGEH 307 Query: 201 DAARRMIGTLLAEMDGFKERKD--KVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSA 258 +A+RR+ L +MDG + + D +V VL ATN PW+LDEA+ R RI++PLPD+++ Sbjct: 308 EASRRVKSEFLVQMDGSQNKFDSRRVFVLAATNIPWELDEALRRRFEKRIFIPLPDIDAR 367 Query: 259 VEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 ++ + + G ++ A +SG ++ ++ + A + +L R Sbjct: 368 KKLIEKSMEGTPKSDEINYDDLAARTEGFSGADVVSLCRTAAINVLRRY-------FRYD 420 Query: 319 T--LKGRDLTTRPLTLD-------DFKYAMARIKSPITKSDVKKYERWAKEF 361 T L+G +LT +L DF+ A+ + + K + W F Sbjct: 421 TKSLRGGELTAAMESLKAELVRNIDFEAALQAVSPSAGPDTMLKCKEWCDSF 472 >gb|AAD27852.1|AF132553_1 (AF132553) BcDNA.GM02885 [Drosophila melanogaster] >gi|7303816|gb|AAF58863.1| (AE003831) TER94 gene product [alt 2] [Drosophila melanogaster] Length = 801 Score = 148 bits (369), Expect = 1e-34 Identities = 116/372 (31%), Positives = 181/372 (48%), Gaps = 32/372 (8%) Query: 15 EFERALSLGHYDKARLIALRCAELLRKIASENLSLSHILLEEAKKWEEKAKNVRKRREGK 74 + E+ + H +A C+E + E + L I LE+ K E ++ E Sbjct: 392 DLEQIAAESHGHVGADLASLCSEAALQQIREKMDL--IDLEDDKIDAEVLASLAVTMENF 449 Query: 75 NEYFDKLKALIKRSTI------TWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQ 122 K R T+ TW DIGGL KK + + + + K ++P + Sbjct: 450 RYAMTKSSPSALRETVVEVPNTTWTDIGGLESVKKELQELVQYPVEHPDKFLKFGMQPSR 509 Query: 123 GILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPS 182 G+L +GPPG GK+LLA A+AN A F SVK +LL+ +FGES + +F AR +P Sbjct: 510 GVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDKARSAAPC 569 Query: 183 VIFIDEVDSLTMKR----VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDE 238 V+F DE+DS+ R AA R+I +L EMDG +K+ V ++ ATN P +D Sbjct: 570 VLFFDELDSIAKARGGNVGDAGGAADRVINQILTEMDGMGAKKN-VFIIGATNRPDIIDP 628 Query: 239 AML--SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIAN 294 A+L RL IY+PLPD S I K +LR + +V L+ +AK V + +SG ++ Sbjct: 629 AILRPGRLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAK--VTQGFSGADLTE 686 Query: 295 V----VKLATMKMLE---EMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPIT 347 + KLA + +E E ++ + D +T F+ AM + ++ Sbjct: 687 ICQRACKLAIRQAIEAEIRREKERAENQNSAMDMDEDDPVPEITSAHFEEAMKFARRSVS 746 Query: 348 KSDVKKYERWAK 359 +D++KYE +A+ Sbjct: 747 DNDIRKYEMFAQ 758 Score = 142 bits (354), Expect = 7e-33 Identities = 87/265 (32%), Positives = 149/265 (55%), Gaps = 16/265 (6%) Query: 88 STITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAV 141 + + ++DIGG R+ I + + L + ++PP+GIL++GPPGTGK+L+A AV Sbjct: 196 NAVGYDDIGGCRKQLAQIKEMVELPLRHPSLFKAIGVKPPRGILMYGPPGTGKTLIARAV 255 Query: 142 ANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR-VSLD 200 AN A FF + +++SK GES + F A + SP++IFIDE+D++ KR + Sbjct: 256 ANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNSPAIIFIDEIDAIAPKRDKTHG 315 Query: 201 DAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSA 258 + RR++ LL MDG K + +IV+ ATN P +D A+ R I + +PD Sbjct: 316 EVERRIVSQLLTLMDGMK-KSSHLIVMAATNRPNSIDPALRRFGRFDREIDIGIPDATGR 374 Query: 259 VEIFKIHLRG--IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLR 316 +E+ +IH + +H DV L ++A E+ + G ++A++ A ++ + E +L D L Sbjct: 375 LEVLRIHTKNMKLHDDVDLEQIAAES--HGHVGADLASLCSEAALQQIRE-KMDLID-LE 430 Query: 317 VSTLKGRDLTTRPLTLDDFKYAMAR 341 + L + +T+++F+YAM + Sbjct: 431 DDKIDAEVLASLAVTMENFRYAMTK 455 >pir||T46169 CDC48-like protein - Arabidopsis thaliana >gi|6630743|emb|CAB64226.1| (AL132958) CDC48-like protein [Arabidopsis thaliana] Length = 815 Score = 148 bits (369), Expect = 1e-34 Identities = 98/297 (32%), Positives = 160/297 (52%), Gaps = 22/297 (7%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKS 135 + +++ ++W DIGGL K+ + + + + K + P +G+L +GPPG GK+ Sbjct: 470 ETVVEVPNVSWEDIGGLENVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKT 529 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSL-TM 194 LLA A+AN A F S+K +LL+ +FGES + +F ARQ +P V+F DE+DS+ T Sbjct: 530 LLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQSAPCVLFFDELDSIATQ 589 Query: 195 KRVSLDD---AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIY 249 + S+ D AA R++ LL EMDG +K V ++ ATN P +D A+L RL IY Sbjct: 590 RGNSVGDAGGAADRVLNQLLTEMDGMNAKK-TVFIIGATNRPDIIDPALLRPGRLDQLIY 648 Query: 250 VPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANV----VKLATMKM 303 +PLPD S +IFK LR + DV L LAK + +SG +I + K A + Sbjct: 649 IPLPDEESRYQIFKSCLRKSPVAKDVDLRALAK--YTQGFSGADITEICQRSCKYAIREN 706 Query: 304 LE-EMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAK 359 +E ++ E ++ + + F+ +M + ++ +D++KY+ +A+ Sbjct: 707 IEKDIEKERKRAESPEAMEEDEEEIAEIKAGHFEESMKYARRSVSDADIRKYQAFAQ 763 Score = 132 bits (328), Expect = 8e-30 Identities = 80/228 (35%), Positives = 128/228 (56%), Gaps = 14/228 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 + ++D+GG+R+ I + + L + ++PP+GILL+GPPG+GK+L+A AVAN Sbjct: 205 VGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVAN 264 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL-DDA 202 A FF + +++SK GES + F A + +PS+IFIDE+DS+ KR + Sbjct: 265 ETGAFFFCINGPEIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEV 324 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSAVE 260 RR++ LL MDG K R VIV+ ATN P +D A+ R I + +PD +E Sbjct: 325 ERRIVSQLLTLMDGLKSRA-HVIVMGATNRPNSIDPALRRFGRFDREIDIGVPDEIGRLE 383 Query: 261 IFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEE 306 + +IH + + DV L R++K+ Y G ++A + A ++ + E Sbjct: 384 VLRIHTKNMKLAEDVDLERVSKDT--HGYVGADLAALCTEAALQCIRE 429 >pir||T05873 hypothetical protein T29A15.170 - Arabidopsis thaliana >gi|4469019|emb|CAB38280.1| (AL035602) putative protein [Arabidopsis thaliana] >gi|7269622|emb|CAB81418.1| (AL161571) putative protein [Arabidopsis thaliana] Length = 398 Score = 147 bits (368), Expect = 2e-34 Identities = 107/308 (34%), Positives = 165/308 (52%), Gaps = 29/308 (9%) Query: 55 EEAKKWEEKAKNVRKRREGK----NEYFDKLKALI---KRSTITWNDIGGLREAKKLIAQ 107 E +KK E K + KR N Y D + + + + IGGL K+ + + Sbjct: 39 EASKKALEHKKEISKRLGRPLVQTNPYEDVIACDVINPDHIDVEFGSIGGLETIKQALYE 98 Query: 108 AIGLSIAKSPI-------EPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSK 160 + L + + + P +G+LL+GPPGTGK++LA A+A A F +V+ S+L+SK Sbjct: 99 LVILPLKRPELFAYGKLLGPQKGVLLYGPPGTGKTMLAKAIAKESGAVFINVRVSNLMSK 158 Query: 161 YFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD-DAARRMIGTLLAEMDGFK- 218 +FG++ KL+SA+FSLA +L P++IFIDEV+S +R S D +A M +A DGF Sbjct: 159 WFGDAQKLVSAVFSLAYKLQPAIIFIDEVESFLGQRRSTDHEAMANMKTEFMALWDGFST 218 Query: 219 ERKDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRG--IHYDVPLS 276 + +V+VL ATN P +LDEA+L RLP + +PD EI K+ L+G + D+ Sbjct: 219 DPHARVMVLAATNRPSELDEAILRRLPQAFEIGIPDRRERAEILKVTLKGERVEPDIDFD 278 Query: 277 RLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVSTLKGRD-LTTRPLTLDDF 335 +A+ + Y+G +I + K A + E+ D R KG+ L RPL+ D Sbjct: 279 HIAR--LCEGYTGSDIFELCKKAAYFPIR----EILDAER----KGKPCLDPRPLSQLDL 328 Query: 336 KYAMARIK 343 + +A K Sbjct: 329 EKVLATSK 336 >gb|AAC02215.1| (AF044488) valosin-containing protein homolog [Trypanosoma brucei] Length = 780 Score = 147 bits (367), Expect = 2e-34 Identities = 98/291 (33%), Positives = 157/291 (53%), Gaps = 20/291 (6%) Query: 85 IKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKSLLA 138 ++ +TW+D+GGL + K+ + + + + K I P+G+L +GPPG GK+LLA Sbjct: 458 VETPNVTWSDVGGLLDVKRELQELVQYPVEFPWKFEKYGISAPKGVLFYGPPGCGKTLLA 517 Query: 139 SAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVS 198 A+A A F S+K +LL+ +FGES + +F AR +P V+F DE+DS+ R Sbjct: 518 KAIATECQANFISIKGPELLTMWFGESEANVRDVFDKARAAAPCVLFFDELDSVARSRGH 577 Query: 199 LDD--AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPD 254 D A+ R+I +L EMDG +K+ V ++ ATN P LD A++ RL IY+PLPD Sbjct: 578 SGDGGASDRVINQILTEMDGMNSKKN-VFIIGATNRPDVLDPAVMRPGRLDQLIYIPLPD 636 Query: 255 VNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANVVKLA-TMKMLEEMNPEL 311 S V I K R + DV L +LA A +SG ++A + + A + + E + E+ Sbjct: 637 KASRVAILKASFRKSPLAPDVDLDQLA--AATHGFSGADLAGICQRACKLAIRESIAKEI 694 Query: 312 S-DPLRVSTLKGRDLTTRP---LTLDDFKYAMARIKSPITKSDVKKYERWA 358 + R + + D P +T + AM + ++ +D++KYE +A Sbjct: 695 QLEEARANGVLNEDQDIDPVPQITRLHVEEAMRGARRSVSDADIRKYELFA 745 Score = 127 bits (316), Expect = 2e-28 Identities = 80/228 (35%), Positives = 128/228 (56%), Gaps = 14/228 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 + ++DIGG R I + + L I I+PP+GIL++GPPG+GK+L+A AVAN Sbjct: 190 VGYDDIGGCRRQLVQIREMVELPIRHPELFKSIGIKPPRGILMYGPPGSGKTLIARAVAN 249 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD-DA 202 A FF + +++SK GES + F + + +P++IFIDE+DS+ KR + Sbjct: 250 ETGAFFFLINGPEIMSKMAGESEGNLRNAFVESEKNAPAIIFIDEIDSIAPKREKAQGEV 309 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSAVE 260 +R++ LL MDG K R +VIV+ ATN P +D A+ R I + +PD +E Sbjct: 310 EKRIVSQLLTLMDGLKGR-SQVIVMAATNRPNAIDPALRRFGRFDREIDIGVPDEIGRLE 368 Query: 261 IFKIHLRGIHYD--VPLSRLAKEAVKRLYSGREIANVVKLATMKMLEE 306 I +IH + + D V + ++AK++ Y G ++A + A M+ + E Sbjct: 369 ILRIHTKNMKLDPNVDVEKIAKDS--HGYVGADLAQLCTEAAMQCVRE 414 >gi|11499558 26S protease regulatory subunit 4 [Archaeoglobus fulgidus] >gi|3122632|sp|O28303|PRS1_ARCFU PUTATIVE 26S PROTEASE REGULATORY SUBUNIT HOMOLOG AF1976 >gi|7435736|pir||G69496 ATP-dependent 26S proteinase regulatory subunit 4 homolog - Archaeoglobus fulgidus >gi|2648566|gb|AAB89280.1| (AE000967) 26S protease regulatory subunit 4 [Archaeoglobus fulgidus] Length = 398 Score = 146 bits (365), Expect = 3e-34 Identities = 94/235 (40%), Positives = 136/235 (57%), Gaps = 17/235 (7%) Query: 86 KRSTITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLAS 139 ++ +++ DIGGL + I +A+ L + K IEPP+G+LL+GPPGTGK+LLA Sbjct: 134 EKPEVSYEDIGGLDVQIEEIREAVELPLLKPELFAEVGIEPPKGVLLYGPPGTGKTLLAK 193 Query: 140 AVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL 199 AVAN ATF V S+ + KY GE ++L+ +F LA++ +PS+IFIDE+D++ +R + Sbjct: 194 AVANQTRATFIRVVGSEFVQKYIGEGARLVREVFQLAKEKAPSIIFIDELDAIAARRTNS 253 Query: 200 DDA----ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLP 253 D + +R + LLAE+DGF R D V V+ ATN LD A+L R I VPLP Sbjct: 254 DTSGDREVQRTMMQLLAELDGFDPRGD-VKVIGATNRIDILDPAILRPGRFDRIIEVPLP 312 Query: 254 DVNSAVEIFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEE 306 ++IFKIH R + DV LA+ + SG +I + A M + E Sbjct: 313 TFEGRIQIFKIHTRKMKLAEDVDFKELAR--ITEGASGADIKAICTEAGMFAIRE 365 >pir||F72504 probable 26S proteinase regulatory subunit APE2012 - Aeropyrum pernix (strain K1) >gi|5105710|dbj|BAA81022.1| (AP000063) 409aa long hypothetical 26S protease regulatory subunit [Aeropyrum pernix] Length = 409 Score = 146 bits (365), Expect = 3e-34 Identities = 103/291 (35%), Positives = 157/291 (53%), Gaps = 38/291 (13%) Query: 73 GKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGIL 125 G+ + K + +R + + D+GGL E + I +A+ L I K+P I+PP+G+L Sbjct: 119 GRYDPLVKAMEVEERPKVFFKDVGGLEEQIREIYEAVVLPI-KNPHLFRELGIDPPKGVL 177 Query: 126 LFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIF 185 L GPPGTGK+LLA AVA ATF V S+L++K+ GE ++L+ +F LAR+ +PS++F Sbjct: 178 LHGPPGTGKTLLAKAVAGETEATFIRVVGSELVNKFIGEGARLVREIFRLAREKAPSILF 237 Query: 186 IDEVDSLTMKRVSL----DDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML 241 IDE+D++ KRV + D +R + LLAE+DGF + D V V+ ATN +D A+L Sbjct: 238 IDEIDAIASKRVDIGTSGDREVQRTMLQLLAELDGF-DPLDNVKVIAATNRLDLIDPAVL 296 Query: 242 --SRLPIRIYVPLPDVNSAVEIFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVK 297 R I VPLP + +EI IH R DV L +AK + +SG ++ VV Sbjct: 297 RPGRFDRIIEVPLPSLRGRLEILGIHTRKAKMAPDVDLEAIAK--LTEGFSGADLKAVVV 354 Query: 298 LATMKMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITK 348 A + +R +T+DD A+ ++K+ + K Sbjct: 355 EAGYNAIRR-------------------GSRVITMDDMIKAVEKVKAALDK 386 >emb|CAC12300.1| (AL445066) VAT-2 protein [Thermoplasma acidophilum] Length = 375 Score = 146 bits (365), Expect = 3e-34 Identities = 115/366 (31%), Positives = 182/366 (49%), Gaps = 46/366 (12%) Query: 21 SLGHYDKARLIALRCAELLRKIAS--------ENLSLSHILLEEAKKWEEKAKNVRKRRE 72 SLGH DKA+ L+ + A+ + L +I+L ++ E E Sbjct: 26 SLGHKDKAKEYYFAAYRLMLEAANASPPDLKKKRLDQCNIILSAYQRVNEN--RTAPAEE 83 Query: 73 GKNEYFDKLKALIKR--------STITWNDIGGLREAKKLIAQAIGLSIAKSPIEPPQ-- 122 ++ + +AL++ +T+ D+ GL + K I I + + Sbjct: 84 KTSDRISEGEALLEEIGLEKPEIPKVTFEDVAGLDDVKNEILGKIVYPMKFKELSQEYNI 143 Query: 123 ----GILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQ 178 G+LL+GPPGTGK+ + A+AN + A F +V + L S++FG K IS LF A Sbjct: 144 QFGGGMLLYGPPGTGKTFIVKAIANEVRARFINVNPASLYSQWFGMFEKNISKLFRAAAL 203 Query: 179 LSPSVIFIDEVDSLTMKR-VSLDDAARRMIGTLLAEMDGFKERKDK-VIVLTATNAPWDL 236 LSPS+IF DE+D+L KR S DAA+R + LL E+ G +K+K + ++ ATN PW++ Sbjct: 204 LSPSIIFFDEIDALVPKRDTSNSDAAKRGVAQLLNEVGGINSQKNKNLFIIAATNNPWEI 263 Query: 237 DEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREI 292 DEAML R I+IYVP PD+ + +IF++++ + ++ + LA++ YSG +I Sbjct: 264 DEAMLRPGRFDIKIYVPPPDIIARKKIFELNMAKVKQAGNIDYNLLAQQT--EGYSGADI 321 Query: 293 ANVVKLATMKMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVK 352 + K A+ + E V + K R + TR L LD + IK I + Sbjct: 322 EFICKKASQNVFME---------AVKSGKQRQVETRDL-LD----VIGSIKPSIDADLLS 367 Query: 353 KYERWA 358 KY +A Sbjct: 368 KYREFA 373 >gb|AAF17568.1|AF202034_1 (AF202034) endoplasmic reticulum membrane fusion protein [Drosophila melanogaster] Length = 799 Score = 146 bits (364), Expect = 5e-34 Identities = 117/372 (31%), Positives = 182/372 (48%), Gaps = 30/372 (8%) Query: 15 EFERALSLGHYDKARLIALRCAELLRKIASENLSLSHILLEEAKKWEEKAKNVRKRREGK 74 + E+ + H +A C+E + E + L I LE+ K E ++ E Sbjct: 392 DLEQIAAESHGHVGADLASLCSEAALQQIREKMDL--IDLEDDKIDAEVLASLAVTMENF 449 Query: 75 NEYFDKLKALIKRSTI------TWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQ 122 K R T+ TW DIGGL KK + + + + K ++P + Sbjct: 450 RYAMTKSSPSALRETVVEVPNTTWTDIGGLESVKKELQELVQYPVEHPDKFLKFGMQPSR 509 Query: 123 GILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPS 182 G+L +GPPG GK+L A A+AN A F SVK +LL+ +FGES + +F +P Sbjct: 510 GVLFYGPPGCGKTLPAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDKGPSAAPC 569 Query: 183 VIFIDEVDSLTMKR---VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEA 239 V+F DE+DS+ R V AA R+I +L EMDG +K+ V ++ ATN P +D A Sbjct: 570 VLFFDELDSIAKSRCGNVGDCGAADRVINQILTEMDGMGAKKN-VFIIGATNRPDIIDPA 628 Query: 240 ML--SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANV 295 +L RL IY+PLPD S I K +LR + +V L+ +AK V + +SG ++ + Sbjct: 629 ILRPGRLDQLIYIPLPDDKSREAILKANLRKFALAKEVDLTYIAK--VTQGFSGADLTEI 686 Query: 296 ----VKLATMKMLE-EMNPELS-DPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKS 349 KLA + +E E+ E + S + D +T F+ AM + ++ + Sbjct: 687 CQRACKLAIRQAIEAEIRREKERAENQNSAMDDEDDPVPEITSAHFEEAMKFARRSVSDN 746 Query: 350 DVKKYERWAKEF 361 D++KYE +A +F Sbjct: 747 DIRKYEMFAPDF 758 Score = 142 bits (354), Expect = 7e-33 Identities = 87/265 (32%), Positives = 149/265 (55%), Gaps = 16/265 (6%) Query: 88 STITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAV 141 + + ++DIGG R+ I + + L + ++PP+GIL++GPPGTGK+L+A AV Sbjct: 196 NAVGYDDIGGCRKQLAQIKEMVELPLRHPSLFKAIGVKPPRGILMYGPPGTGKTLIARAV 255 Query: 142 ANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR-VSLD 200 AN A FF + +++SK GES + F A + SP++IFIDE+D++ KR + Sbjct: 256 ANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNSPAIIFIDEIDAIAPKRDKTHG 315 Query: 201 DAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSA 258 + RR++ LL MDG K + +IV+ ATN P +D A+ R I + +PD Sbjct: 316 EVERRIVSQLLTLMDGMK-KSSHLIVMAATNRPNSIDPALRRFGRFDREIDIGIPDATGR 374 Query: 259 VEIFKIHLRG--IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLR 316 +E+ +IH + +H DV L ++A E+ + G ++A++ A ++ + E +L D L Sbjct: 375 LEVLRIHTKNMKLHDDVDLEQIAAES--HGHVGADLASLCSEAALQQIRE-KMDLID-LE 430 Query: 317 VSTLKGRDLTTRPLTLDDFKYAMAR 341 + L + +T+++F+YAM + Sbjct: 431 DDKIDAEVLASLAVTMENFRYAMTK 455 >gb|AAF24564.1|AC007764_6 (AC007764) F22C12.12 [Arabidopsis thaliana] Length = 825 Score = 145 bits (363), Expect = 6e-34 Identities = 90/275 (32%), Positives = 153/275 (54%), Gaps = 15/275 (5%) Query: 48 SLSHILLEEAKKWEEKAKNVRKRREG---KNEYFDKLKALI---KRSTITWNDIGGLREA 101 S++ + +E + E KA+ V + NE+ +++ + + +T+ DIG L E Sbjct: 443 SVTTVSSKEEPEKEAKAEKVTPKAPEVAPDNEFEKRIRPEVIPAEEINVTFKDIGALDEI 502 Query: 102 KKLIAQAIGLSIAKSPI------EPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKAS 155 K+ + + + L + + + +P +GILLFGPPGTGK++LA A+A A+F +V S Sbjct: 503 KESLQELVMLPLRRPDLFTGGLLKPCRGILLFGPPGTGKTMLAKAIAKEAGASFINVSMS 562 Query: 156 DLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSL--TMKRVSLDDAARRMIGTLLAE 213 + SK+FGE K + ALF+LA ++SP++IF+DEVDS+ RV +A R++ ++ Sbjct: 563 TITSKWFGEDEKNVRALFTLASKVSPTIIFVDEVDSMLGQRTRVGEHEAMRKIKNEFMSH 622 Query: 214 MDGFKERK-DKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYD 272 DG + ++++VL ATN P+DLDEA++ R RI V LP V + +I + L D Sbjct: 623 WDGLMTKPGERILVLAATNRPFDLDEAIIRRFERRIMVGLPAVENREKILRTLLAKEKVD 682 Query: 273 VPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEM 307 L + Y+G ++ N+ A + + E+ Sbjct: 683 ENLDYKELAMMTEGYTGSDLKNLCTTAAYRPVREL 717 >gb|AAG19767.1| (AE005062) cell division cycle protein; Cdc48a [Halobacterium sp. NRC-1] Length = 691 Score = 143 bits (356), Expect = 4e-33 Identities = 87/233 (37%), Positives = 132/233 (56%), Gaps = 11/233 (4%) Query: 83 ALIKRSTITWNDIGGLREAKKLIAQAIGLS------IAKSPIEPPQGILLFGPPGTGKSL 136 A ++ T T+ DIGGL AK+ + + + + P G+LL GPPGTGK++ Sbjct: 424 ASVQTPTTTYQDIGGLDRAKREVVRTVEWPQRYPALFERLDAAAPTGVLLHGPPGTGKTM 483 Query: 137 LASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR 196 LA AVA S +A F SV +L+++Y GES + + LF AR+L+P+V+F+DEVDSL R Sbjct: 484 LAKAVAASTDANFLSVDGPELMNRYVGESERGVRDLFERARRLAPAVVFLDEVDSLAPAR 543 Query: 197 VSLD-DAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLP 253 D A+ R++ LL E+DG R V VL ATN +D A+L R+ ++ VP+P Sbjct: 544 HDTDTGASERVVSQLLTELDGLSPR-GSVAVLAATNRRESVDPALLRPGRIETQVAVPIP 602 Query: 254 DVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEE 306 D ++ IF++ L G+ + A A Y+G +IA VV+ + +E+ Sbjct: 603 DQDARAAIFEVQLDGVATG-RIDTTALAAATTGYTGSDIAGVVREGALLAMED 654 >gb|AAG19776.1| (AE005063) cell division cycle protein; Cdc48b [Halobacterium sp. NRC-1] Length = 759 Score = 143 bits (356), Expect = 4e-33 Identities = 94/284 (33%), Positives = 153/284 (53%), Gaps = 21/284 (7%) Query: 91 TWNDIGGLREAKKLIAQAIGLSI------AKSPIEPPQGILLFGPPGTGKSLLASAVANS 144 TW D+GGL + K+ + + I + ++ ++ +G+LL+GPPGTGK+LLA AVAN Sbjct: 467 TWADVGGLTDTKERLRETIQWPLDYPDVFSEMDLQSAKGVLLYGPPGTGKTLLAKAVANE 526 Query: 145 LNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR---VSLDD 201 N+ F SVK +LL+KY GES K + +F AR +P+V+F DE+D++ +R S Sbjct: 527 ANSNFISVKGPELLNKYVGESEKGVREVFEKARSNAPTVVFFDEIDAIAGQRGRATSDSG 586 Query: 202 AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAV 259 R++ LL E+DG + +D V+V T +N P +D+A+L RL I+VP+PD ++ Sbjct: 587 VGERVVSQLLTELDGIEALEDVVVVAT-SNRPDLIDDALLRPGRLDRHIHVPVPDADARR 645 Query: 260 EIFKIHLRG--IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRV 317 I +H R + DV L +A+ + G ++ +V+ ATM E + DP Sbjct: 646 AILDVHTRDKPLADDVDLDVVAQRMDG--FVGADVEALVREATMNATREFINSV-DPADA 702 Query: 318 STLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 S G +T+ F+ A+ + + + + YE + F Sbjct: 703 SDSVG----NVRVTMAHFEAALGEVTASVDADVKENYEEIEQRF 742 Score = 140 bits (350), Expect = 2e-32 Identities = 89/265 (33%), Positives = 148/265 (55%), Gaps = 16/265 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 +T+ DIGGL + + + I L + I+PP+G+LL GPPGTGK+L+A AVAN Sbjct: 193 VTYEDIGGLDGELEQVREMIELPMRHPELFQQLGIDPPKGVLLHGPPGTGKTLIAKAVAN 252 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR-VSLDDA 202 ++A F ++ +++SKY+GES + + +F A + +P+++F+DE+DS+ KR + D Sbjct: 253 EIDAHFETISGPEIMSKYYGESEEKLREVFDEAEENAPAIVFVDELDSIAPKRGETQGDV 312 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVE 260 RR++ LL+ MDG ++R D V V+ ATN +D A+ R I + +PD + E Sbjct: 313 ERRVVAQLLSLMDGLEDRGD-VTVIAATNRVDAIDPALRRGGRFDREIEIGVPDQDGRKE 371 Query: 261 IFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 I ++H RG+ D+ L A+ + G +I ++ K A M L + P++ L Sbjct: 372 ILQVHTRGMPLVEDIDLDDYAEST--HGFVGADIESLAKEAAMNALRRVRPDID--LESD 427 Query: 319 TLKGRDLTTRPLTLDDFKYAMARIK 343 + L + +T DFK A+ I+ Sbjct: 428 EIDAELLESISITEADFKRALNGIE 452 >gb|AAF74998.1| (AF199367) cdc48-like protein [Entamoeba histolytica] Length = 772 Score = 142 bits (355), Expect = 5e-33 Identities = 91/297 (30%), Positives = 159/297 (52%), Gaps = 22/297 (7%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSI------AKSPIEPPQGILLFGPPGTGKS 135 + +++ + W DIGGL + K+ + + + + K +EP +G+L FGPPG GK+ Sbjct: 465 ETVVEIPNVKWEDIGGLEDVKRELKEVVQYPVEFPDKFTKFGMEPSKGVLFFGPPGCGKT 524 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 LLA AVA+ A F S+K +LL+ ++GES + +F ARQ +P V+F DE+DS+ Sbjct: 525 LLAKAVASQCKANFISIKGPELLTMWYGESEANVRDVFDKARQAAPCVLFFDELDSIGRA 584 Query: 196 R----VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIY 249 R +A R++ LL EMDG ++K +V ++ ATN P LD A+L RL ++ Sbjct: 585 RGGGAGDAGGSADRILNQLLTEMDGVGKKK-QVFIIGATNRPDILDPALLRPGRLDQLLF 643 Query: 250 VPLPDVNSAVEIFKIHLRG--IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEM 307 +PLPD S + I + LR + DV L +A+ +SG ++A +V+ A + + + Sbjct: 644 IPLPDKASRISILQAKLRNSPVAPDVDLDWIAEHTEN--FSGADLAEIVQRACKEAIRDT 701 Query: 308 NPELSDPLRVSTLKGRD----LTTRP-LTLDDFKYAMARIKSPITKSDVKKYERWAK 359 EL+ + D + +P + + F A+ + ++ ++++Y +A+ Sbjct: 702 INELAVAEAEKAAQPEDQKMEIEVKPMIKVKHFNAALRDARRSVSDIEIQRYNMYAE 758 Score = 124 bits (309), Expect = 1e-27 Identities = 85/249 (34%), Positives = 131/249 (52%), Gaps = 17/249 (6%) Query: 92 WNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVANSL 145 ++DIGG R I + + L + I+PP+G+LL+GPPG GK+++A AVAN Sbjct: 202 YDDIGGCRRQLGQIREMVELPLRHPQLFQAIGIKPPKGVLLYGPPGCGKTMIARAVANET 261 Query: 146 NATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR-VSLDDAAR 204 + +++SK GES + F+ A + +P++IFIDE+DS+ KR + + R Sbjct: 262 GVFLILINGPEIMSKMAGESEGNLREAFAEAEKNAPALIFIDEIDSIAPKRDKAQGEVER 321 Query: 205 RMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSAVEIF 262 R++ LL MDG K R + VIV+ ATN P +D A+ R I + +PD +EI Sbjct: 322 RVVAQLLTLMDGMKSRSN-VIVMAATNRPNAIDSALRRFGRFDREIDIGVPDETGRLEIL 380 Query: 263 KIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPEL---SDPLRV 317 IH + I DV L ++AKE Y G ++A + A M + E + +D + V Sbjct: 381 NIHTKKMKIADDVDLLQIAKET--HGYVGADLAQLCTEAAMLCIRENMAHVDVEADSIPV 438 Query: 318 STLKGRDLT 326 L G +T Sbjct: 439 EVLNGMKVT 447 >gb|AAD31547.1|U53149_5 (U53149) Contains similarity to Pfam domain: PF00004 (AAA), Score=233.7, E-value=8.6e-67, N=1 [Caenorhabditis elegans] Length = 512 Score = 141 bits (351), Expect = 2e-32 Identities = 93/294 (31%), Positives = 153/294 (51%), Gaps = 23/294 (7%) Query: 81 LKALIKRSTITWNDIGGLREAKKLIAQAIGL-----SIAKSPIEPPQGILLFGPPGTGKS 135 L ++ + + +D+ G AK + +A+ L ++ K +P +GILLFGPPG GK+ Sbjct: 227 LDEVLDNTGVRMDDVAGCHSAKAALEEAVILPALNPNLFKGLRQPVKGILLFGPPGNGKT 286 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 LLA AVA FF++ AS L SK+ G+S K I LF +AR PS+IFIDE+DS+ + Sbjct: 287 LLAKAVAGESKQMFFNISASSLTSKWVGDSEKTIRGLFQIARNAQPSIIFIDEIDSILCE 346 Query: 196 RVSLD-DAARRMIGTLLAEMDG-FKERKDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLP 253 R D + +RRM L + DG D+++V+ ATN P +LD+A+L R P RI + LP Sbjct: 347 RSEKDAEVSRRMKTEFLVQFDGATSSADDRILVIGATNRPHELDDAVLRRFPKRIMLNLP 406 Query: 254 DVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRL------YSGREIANVVKLATMKMLEEM 307 D + E+ L+ + + L ++ + +S ++ + K A M + E+ Sbjct: 407 DEEARKELITKTLKKHNM---MDGLISSDIRYIASNTSGFSNSDLVALCKEAAMVPIREI 463 Query: 308 NPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 D ++S G + R + DF A+ I+ ++ + K +++ F Sbjct: 464 -----DRSKLSMTDGEKI--RKIRASDFDTALRTIRPSTSQKIMSKLSDFSRSF 510 >dbj|BAA83371.1| (AP000391) Similar to Arabidopsis thaliana chromosome II BAC F17K2 genomic sequence; hypothetical protein (AC003680) [Oryza sativa] Length = 427 Score = 141 bits (351), Expect = 2e-32 Identities = 104/311 (33%), Positives = 155/311 (49%), Gaps = 62/311 (19%) Query: 70 RREGKNEYFDKLKALIKRS------TITWNDIGGLREAKKLIAQAIGLSIAKSPI----- 118 +R G N Y DKL +I + + W D+ GL +AK+ + + + L + + Sbjct: 157 QRAGAN-YDDKLVEMINTTIVDRSPAVKWEDVAGLDKAKQALMEMVILPTKRRDLFTGLR 215 Query: 119 EPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQ 178 P +G+LLFGPPG GK++LA AVA+ ATFF+V AS L SK+ Sbjct: 216 RPARGLLLFGPPGNGKTMLAKAVASESEATFFNVSASSLTSKW----------------- 258 Query: 179 LSPSVIFIDEVDSLTMKRVSLDDAARRMIGTLLAEMDGFKERKDK-VIVLTATNAPWDLD 237 ID V ++ + + +DA+RR+ L + DG D VIV+ ATN P +LD Sbjct: 259 -------IDSV--MSARLANENDASRRLKSEFLIQFDGVTSNPDDLVIVIGATNKPQELD 309 Query: 238 EAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVK 297 +A+L RL RIYVPLPD N + K L+G + LSR YSG ++ + + Sbjct: 310 DAVLRRLVKRIYVPLPDPNVRRLLLKTQLKGQSF--KLSR---------YSGSDLRALCE 358 Query: 298 LATMKMLEEMNPELSDPLRVSTLKGRDL-------TTRPLTLDDFKYAMARIKSPITKSD 350 A M + E+ P+ + T+K + + RPL +DFK AM I+ + KS Sbjct: 359 EAAMMPIRELGPQ-----NILTIKANQVFRVTSSYSLRPLKYEDFKKAMTVIRPSLQKSK 413 Query: 351 VKKYERWAKEF 361 + E+W +EF Sbjct: 414 WDELEKWNEEF 424 >gb|AAG20864.1| (AE005154) cell division cycle protein; Cdc48d [Halobacterium sp. NRC-1] Length = 737 Score = 141 bits (351), Expect = 2e-32 Identities = 91/265 (34%), Positives = 151/265 (56%), Gaps = 16/265 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 +T+ DIGGL + + + + I L + IEPP+G+LL GPPGTGK+L+A AVAN Sbjct: 190 LTYEDIGGLDDELEQVREMIELPMRHPELFGTLGIEPPKGVLLHGPPGTGKTLIAKAVAN 249 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD-DA 202 ++A F ++ +++SKY+GES + + +F A + +P+++FIDE+DS+ KR + D Sbjct: 250 EIDAHFQTISGPEIMSKYYGESEEQLRDVFEEAEENAPAIVFIDELDSIAPKREDVSGDV 309 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVE 260 RR++ LL+ MDG +ER ++ V+ TN +D A+ R I + +PD + + Sbjct: 310 ERRVVAQLLSLMDGLEER-GQLTVIGTTNRVDAVDPALRRPGRFDREIEIGVPDHDGREK 368 Query: 261 IFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 I +IH RG+ V L R A+ + + G ++ N+VK + M L + P+L L Sbjct: 369 ILQIHTRGMPLGDGVDLDRYAENT--QGFVGADLENLVKESAMHALRRIRPDLD--LDEE 424 Query: 319 TLKGRDLTTRPLTLDDFKYAMARIK 343 + L + +T +DFK A+ I+ Sbjct: 425 EIPADILDSIEVTENDFKEALRGIE 449 Score = 141 bits (351), Expect = 2e-32 Identities = 85/232 (36%), Positives = 135/232 (57%), Gaps = 20/232 (8%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 +TW+ +GGL +AK+ + + + + + +EP +G+LL+GPPGTGK+LLA AVAN Sbjct: 463 VTWDHVGGLDDAKERLQETVQWPLEHADAYEQVALEPAKGVLLYGPPGTGKTLLAKAVAN 522 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR---VSLD 200 N+ F S+K +L +KY GES + + +FS AR+ +P+V+F DE+D++ +R V Sbjct: 523 EANSNFISIKGPELFNKYVGESERGVREVFSKARENAPTVVFFDEIDAIASERGQGVGDS 582 Query: 201 DAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSA 258 + R++ LL E+DG +E +D ++V+ TN P +D+A+L RL + V PD + Sbjct: 583 NVGERVVSQLLTELDGLEELED-IVVIATTNRPDLIDDALLRPGRLDRHVAVDEPDEAAR 641 Query: 259 VEIFKIHLRGIHYDVPLSR--LAKEAVKRL--YSGREIANVVKLATMKMLEE 306 EIF+IH D PL+ E V+R Y G +I V + A + E Sbjct: 642 REIFEIHTE----DKPLAEDVDVDELVERTDGYVGADIEAVCREAATVAVRE 689 >sp|P71408|FTSH_HELPY CELL DIVISION PROTEIN FTSH HOMOLOG >gi|7446580|pir||E64653 cell division protein - Helicobacter pylori (strain 26695) >gi|2314219|gb|AAD08115.1| (AE000614) cell division protein (ftsH) [Helicobacter pylori 26695] Length = 632 Score = 140 bits (350), Expect = 2e-32 Identities = 90/258 (34%), Positives = 137/258 (52%), Gaps = 18/258 (6%) Query: 60 WEEKAKNVRKRREGKNEYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGL-----S 112 W A ++K G K LI ++ + +ND+ G EAK+ + + + Sbjct: 135 WMFMANRMQKNMGGGIFGMGSAKKLINAEKPNVRFNDMAGNEEAKEEVVEIVDFLKYPER 194 Query: 113 IAKSPIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISAL 172 A + P+G+LL GPPGTGK+LLA AVA + FFS+ S + + G + + L Sbjct: 195 YANLGAKIPKGVLLVGPPGTGKTLLAKAVAGEAHVPFFSMGGSSFIEMFVGLGASRVRDL 254 Query: 173 FSLARQLSPSVIFIDEVDSLTMKR-----VSLDDAARRMIGTLLAEMDGFKERKDKVIVL 227 F A++ +PS+IFIDE+D++ R VS +D + + LLAEMDGF VIVL Sbjct: 255 FETAKKQAPSIIFIDEIDAIGKSRAAGGVVSGNDEREQTLNQLLAEMDGFGSENAPVIVL 314 Query: 228 TATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHY--DVPLSRLAKEAV 283 ATN P LD A++ R ++ V PD N VEI K+H++G+ DV L +AK + Sbjct: 315 AATNRPEILDPALMRPGRFDRQVLVDKPDFNGRVEILKVHIKGVKLANDVNLQEVAK--L 372 Query: 284 KRLYSGREIANVVKLATM 301 +G ++AN++ A + Sbjct: 373 TAGLAGADLANIINEAAL 390 >sp|Q9ZM66|FTSH_HELPJ CELL DIVISION PROTEIN FTSH HOMOLOG >gi|7446579|pir||D71941 ATP-dependent zinc metallopeptidase - Helicobacter pylori (strain J99) >gi|4154882|gb|AAD05932.1| (AE001471) ATP-DEPENDENT ZINC METALLOPEPTIDASE [Helicobacter pylori J99] Length = 632 Score = 140 bits (349), Expect = 3e-32 Identities = 89/258 (34%), Positives = 137/258 (52%), Gaps = 18/258 (6%) Query: 60 WEEKAKNVRKRREGKNEYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGL-----S 112 W A ++K G K LI ++ + +ND+ G EAK+ + + + Sbjct: 135 WMFMANRMQKNMGGGIFGMGSAKKLINAEKPNVRFNDMAGNEEAKEEVVEIVDFLKYPER 194 Query: 113 IAKSPIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISAL 172 A + P+G+LL GPPGTGK+LLA AVA + FFS+ S + + G + + L Sbjct: 195 YANLGAKIPKGVLLVGPPGTGKTLLAKAVAGEAHVPFFSMGGSSFIEMFVGLGASRVRDL 254 Query: 173 FSLARQLSPSVIFIDEVDSLTMKR-----VSLDDAARRMIGTLLAEMDGFKERKDKVIVL 227 F A++ +PS+IFIDE+D++ R +S +D + + LLAEMDGF VIVL Sbjct: 255 FETAKKQAPSIIFIDEIDAIGKSRAAGGMISGNDEREQTLNQLLAEMDGFGSENAPVIVL 314 Query: 228 TATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHY--DVPLSRLAKEAV 283 ATN P LD A++ R ++ V PD N VEI K+H++G+ DV L +AK + Sbjct: 315 AATNRPEILDPALMRPGRFDRQVLVDKPDFNGRVEILKVHIKGVKLANDVNLQEVAK--L 372 Query: 284 KRLYSGREIANVVKLATM 301 +G ++AN++ A + Sbjct: 373 TAGLAGADLANIINEAAL 390 >pir||T23322 hypothetical protein K04G2.3 - Caenorhabditis elegans >gi|3878262|emb|CAB00040.1| (Z75712) contains similarity to Pfam domain: PF00004 (ATPases associated with various cellular activities (AAA)), Score=305.8, E-value=1.6e-88, N=1~cDNA EST yk353e8.5 comes from this gene [Caenorhabditis elegans] Length = 724 Score = 139 bits (348), Expect = 3e-32 Identities = 89/235 (37%), Positives = 133/235 (55%), Gaps = 14/235 (5%) Query: 84 LIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFGPPGTGKSL 136 +++ ++WNDIGG E K I QA+ + K P I+PP GILL+GPPG K+L Sbjct: 450 ILEVPNVSWNDIGGNEELKLEIQQAV-IWPQKHPEAFERFGIDPPAGILLYGPPGCSKTL 508 Query: 137 LASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR 196 +A A+A+ F +VK +L SK+ G+S K I LFS ARQ++P+++F DE+D++ R Sbjct: 509 IARALASEAKMNFLAVKGPELFSKWVGDSEKAIRDLFSRARQVAPTIVFFDEIDAVGSSR 568 Query: 197 VS--LDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPL 252 S + R++ LL E+DG E+ +VI+L ATN P LD A+L RL IYV L Sbjct: 569 GSEKSSGVSDRVLAQLLTELDGL-EKSSRVILLAATNRPDQLDSALLRPGRLDRAIYVGL 627 Query: 253 PDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRL-YSGREIANVVKLATMKMLEE 306 P + I ++ + + +D + + K K YSG E+ V + A M + E Sbjct: 628 PCEVTRRAILEMRTKKMKFDDTVRTIDKLVEKTSGYSGAELVAVCRTAAMFAMRE 682 >gb|AAF91246.1|AF227502_1 (AF227502) proteasome regulatory ATPase subunit 4 [Trypanosoma brucei] Length = 399 Score = 139 bits (348), Expect = 3e-32 Identities = 83/234 (35%), Positives = 137/234 (58%), Gaps = 16/234 (6%) Query: 81 LKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGK 134 ++ + I++ +IGGL+E + + + + L + I PP+G+LL+GPPGTGK Sbjct: 131 MQVMENEKNISFQEIGGLQEQMRQMREVVELPLTNPELFVRVGISPPKGVLLYGPPGTGK 190 Query: 135 SLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTM 194 +LLA A+A++++A F + AS ++ KY GES++++ +F+ AR P +IFIDEVD++ Sbjct: 191 TLLAKAIASNVDAAFLKIVASSIVDKYIGESARVLREMFAFARDHEPCIIFIDEVDAIGG 250 Query: 195 KRV---SLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIY 249 KR+ S D +R + LL +MDGF E+ KV V+ ATN P LD A++ RL +I Sbjct: 251 KRIEGSSSDREVQRTLMELLHQMDGF-EKLGKVKVIMATNRPDTLDPALMRPGRLDRKIE 309 Query: 250 VPLPDVNSAVEIFKIHLRGI--HYDVPLSRLAKEAVKRLYSGREIANVVKLATM 301 + LP+ +++ KIH I D+ + K + ++G ++ NV A M Sbjct: 310 IGLPNEAGRLDVLKIHASKITKQGDIDYDSIVK--LSEGFNGADLRNVCTEAGM 361 >emb|CAA67594.1| (X99207) smallminded [Drosophila melanogaster] Length = 943 Score = 139 bits (347), Expect = 4e-32 Identities = 103/300 (34%), Positives = 151/300 (50%), Gaps = 31/300 (10%) Query: 80 KLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFGPPGT 132 K + I TW+DIG L + ++ + A+ L+ K P + P G+LL GPPG Sbjct: 648 KREGFITVPDTTWDDIGALEKIREELKLAV-LAPVKYPEMLERLGLTAPSGVLLCGPPGC 706 Query: 133 GKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSL 192 GK+LLA A+AN F SVK +L++ Y GES + + A F AR +P VIF DE DSL Sbjct: 707 GKTLLAKAIANEAGINFISVKGPELMNMYVGESERAVRACFQRARNSAPCVIFFDEFDSL 766 Query: 193 TMKRVSLDD---AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIR 247 KR D + R++ LL EMDG +ERK V +L ATN P +D A+L RL Sbjct: 767 CPKRSDGGDGNNSGTRIVNQLLTEMDGVEERKG-VYILAATNRPDIIDPAILRPGRLDTI 825 Query: 248 IYVPLPDVNSAVEIFKIHLRG-----IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMK 302 +YV P+ + EI K + + DV L +A A Y+G ++A +VK A+M Sbjct: 826 LYVGFPEQSERTEILKATTKNGKRPVLADDVDLDEIA--AQTEGYTGADLAGLVKQASMF 883 Query: 303 MLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEFA 362 L + L DL R F+ A+ +++ + + D K Y++ ++A Sbjct: 884 SLRQ-------SLNNGDTNLDDLCVRS---QHFQEALQQLRPSVNEQDRKIYDKLRLKYA 933 Score = 99.5 bits (244), Expect = 5e-20 Identities = 96/371 (25%), Positives = 172/371 (45%), Gaps = 28/371 (7%) Query: 9 VQKCQEEFERALSLGHYDKARLIALRCAELLRKIASENLSLSHILLEEAKKWEEKAKNVR 68 +++ EE K I + +E ++K+ + + L E+A + +NV Sbjct: 159 LKRLMEEVPEIAVAAKKAKPNTIHVSSSEAIQKLHQVVGNRAKNLSEDAVPRSKDHRNVP 218 Query: 69 K--RREGKNEYFDKLKAL-----IKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP---- 117 ++ +N+ D+L+ ++ T ++ DIGG+ K + + L KSP Sbjct: 219 GLYQQLHQNQSRDRLRKFKRDLEVQHPTESFRDIGGMDSTLKELCEM--LIHIKSPEFYF 276 Query: 118 ---IEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFS 174 + P +G+LL GPPG GK+ LA A++ L + A++L+ GES + I +F Sbjct: 277 QLGLLPSRGLLLHGPPGCGKTFLARAISGQLKMPLMEIPATELIGGISGESEERIREVFD 336 Query: 175 LARQLSPSVIFIDEVDSLTMKRV-SLDDAARRMIGTLLAEMDGFK--ERKDKVIVLTATN 231 A SP V+FIDE+D++ R + D RR++ L++ +D K E V+V+ AT Sbjct: 337 QAIGYSPCVLFIDEIDAIGGNRQWASKDMERRIVSQLISSLDNLKANEFGQSVVVIAATT 396 Query: 232 APWDLDEAM--LSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSG 289 P LD + + R I + +P EI +I G+ D L+ + Y G Sbjct: 397 RPDVLDPGLRRIGRFDHEIAIHIPSRKERREILRIQCEGLSVDPKLNYDKIAELTPGYVG 456 Query: 290 REIANVVKLATMKMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKS 349 ++ +V A ++ + + L ++ K ++TT +TLDD + + ++P+ S Sbjct: 457 ADLMALVSRAASVAVKRRSMKKFRELHAASEK--NMTT--VTLDDDEPSEDAGETPVPDS 512 Query: 350 DVKKYERWAKE 360 K E AK+ Sbjct: 513 ---KGEETAKD 520 >gb|AAF50566.1| (AE003559) smid gene product [Drosophila melanogaster] Length = 944 Score = 139 bits (347), Expect = 4e-32 Identities = 103/300 (34%), Positives = 151/300 (50%), Gaps = 31/300 (10%) Query: 80 KLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFGPPGT 132 K + I TW+DIG L + ++ + A+ L+ K P + P G+LL GPPG Sbjct: 649 KREGFITVPDTTWDDIGALEKIREELKLAV-LAPVKYPEMLERLGLTAPSGVLLCGPPGC 707 Query: 133 GKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSL 192 GK+LLA A+AN F SVK +L++ Y GES + + A F AR +P VIF DE DSL Sbjct: 708 GKTLLAKAIANEAGINFISVKGPELMNMYVGESERAVRACFQRARNSAPCVIFFDEFDSL 767 Query: 193 TMKRVSLDD---AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIR 247 KR D + R++ LL EMDG +ERK V +L ATN P +D A+L RL Sbjct: 768 CPKRSDGGDGNNSGTRIVNQLLTEMDGVEERKG-VYILAATNRPDIIDPAILRPGRLDTI 826 Query: 248 IYVPLPDVNSAVEIFKIHLRG-----IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMK 302 +YV P+ + EI K + + DV L +A A Y+G ++A +VK A+M Sbjct: 827 LYVGFPEQSERTEILKATTKNGKRPVLADDVDLDEIA--AQTEGYTGADLAGLVKQASMF 884 Query: 303 MLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEFA 362 L + L DL R F+ A+ +++ + + D K Y++ ++A Sbjct: 885 SLRQ-------SLNNGDTNLDDLCVRS---QHFQEALQQLRPSVNEQDRKIYDKLRLKYA 934 Score = 99.8 bits (245), Expect = 4e-20 Identities = 97/367 (26%), Positives = 173/367 (46%), Gaps = 28/367 (7%) Query: 13 QEEFERALSLGHYDKARLIALRCAELLRKIASENLSLSHILLEEAKKWEEKAKNVRK--R 70 +E E A++ K I + +E ++K+ + + L E+A + +NV + Sbjct: 164 EEVPEIAVAAKKVAKPNTIHVSSSEAIQKLHQVVGNRAKNLSEDAVPRSKDHRNVPGLYQ 223 Query: 71 REGKNEYFDKLKAL-----IKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP-------I 118 + +N+ D+L+ ++ T ++ DIGG+ K + + L KSP + Sbjct: 224 QLHQNQSRDRLRKFKRDLEVQHPTESFRDIGGMDSTLKELCEM--LIHIKSPEFYFQLGL 281 Query: 119 EPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQ 178 P +G+LL GPPG GK+ LA A++ L + A++L+ GES + I +F A Sbjct: 282 LPSRGLLLHGPPGCGKTFLARAISGQLKMPLMEIPATELIGGISGESEERIREVFDQAIG 341 Query: 179 LSPSVIFIDEVDSLTMKRV-SLDDAARRMIGTLLAEMDGFK--ERKDKVIVLTATNAPWD 235 SP V+FIDE+D++ R + D RR++ L++ +D K E V+V+ AT P Sbjct: 342 YSPCVLFIDEIDAIGGNRQWASKDMERRIVSQLISSLDNLKANEFGQSVVVIAATTRPDV 401 Query: 236 LDEAM--LSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIA 293 LD + + R I + +P EI +I G+ D L+ + Y G ++ Sbjct: 402 LDPGLRRIGRFDHEIAIHIPSRKERREILRIQCEGLSVDPKLNYDKIAELTPGYVGADLM 461 Query: 294 NVVKLATMKMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKK 353 +V A ++ + + L ++ K ++TT +TLDD + + ++P+ S K Sbjct: 462 ALVSRAASVAVKRRSMKKFRELHAASEK--NMTT--VTLDDDEPSEDAGETPVPDS---K 514 Query: 354 YERWAKE 360 E AK+ Sbjct: 515 GEETAKD 521 >gb|AAB66377.1| (U97567) FtsH [Helicobacter pylori] Length = 632 Score = 139 bits (346), Expect = 6e-32 Identities = 89/258 (34%), Positives = 136/258 (52%), Gaps = 18/258 (6%) Query: 60 WEEKAKNVRKRREGKNEYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGL-----S 112 W A ++K G K LI ++ + +ND+ G EAK+ + + + Sbjct: 135 WMFMANRMQKNMGGGIFGMGSAKKLINAEKPNVRFNDMAGNEEAKEEVVEIVDFLKYPER 194 Query: 113 IAKSPIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISAL 172 A + P+G+LL GPPGTGK+LLA AVA + FFS+ S + + G + + L Sbjct: 195 YANLGAKIPKGVLLVGPPGTGKTLLAKAVAGEAHVPFFSMGGSSFIEMFVGLGASRVRDL 254 Query: 173 FSLARQLSPSVIFIDEVDSLTMKR-----VSLDDAARRMIGTLLAEMDGFKERKDKVIVL 227 F A++ +PS+IFIDE+D++ R VS +D + + LAEMDGF VIVL Sbjct: 255 FETAKKQAPSIIFIDEIDAIGKSRAAGGVVSGNDEREQTLNQFLAEMDGFGSENAPVIVL 314 Query: 228 TATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHY--DVPLSRLAKEAV 283 ATN P LD A++ R ++ V PD N VEI K+H++G+ DV L +AK + Sbjct: 315 AATNRPEILDPALMRPGRFDRQVLVDKPDFNGRVEILKVHIKGVKLANDVNLQEVAK--L 372 Query: 284 KRLYSGREIANVVKLATM 301 +G ++AN++ A + Sbjct: 373 TAGLAGADLANIINEAAL 390 >gb|AAG10801.1|AC022284_6 (AC022284) L3377.6 [Leishmania major] Length = 361 Score = 138 bits (344), Expect = 1e-31 Identities = 86/272 (31%), Positives = 145/272 (52%), Gaps = 16/272 (5%) Query: 85 IKRSTITWNDIGGLREAKKLIAQAIG-------LSIAKSPIEPPQGILLFGPPGTGKSLL 137 I + + ++D+GGL + K + + I L K+ P+G+LL+GPPGTGK+LL Sbjct: 92 IDKIDVDFSDVGGLEDVKDALTEHIKWPFQHQELFSGKTVRSHPKGVLLYGPPGTGKTLL 151 Query: 138 ASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRV 197 A A+A L +F +V + SK+ G++ + +A+F+LA ++SP VIF+DE+DSL R Sbjct: 152 ARALAKELGCSFINVNTESIFSKWVGDTERNAAAVFTLAAKISPCVIFVDEIDSLLSSRS 211 Query: 198 SLDDAARRMIGTL-LAEMDGFKERKD-KVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDV 255 ++D T+ + DG ++ D ++IV+ ATN + +D+A+ RLP+++ VP PD Sbjct: 212 AMDATPHMHAKTIFMTHWDGLEKDSDARIIVVGATNRRFTIDDAIRRRLPLQLEVPPPDA 271 Query: 256 NSAVEIFKIHL-RGIHYDVPLSRLAKEAVKRL--YSGREIANVVKLATMKMLEEMNPELS 312 + +I I L + Y+ L + + Y+G +++ + K A + L EM + Sbjct: 272 KAREKILSILLAHDLEYNPKKDGLIRYVALKTAEYTGSDLSELCKAAALMPLREMESMKA 331 Query: 313 DPLRVSTLKGRDLTTRPLTLDDFKYAMARIKS 344 T PLT F AM R+K+ Sbjct: 332 G----GASSAAPETVPPLTQQHFDKAMERVKA 359 >pir||T50928 calmodulin-binding protein [imported] - Arabidopsis thaliana >gi|6760428|gb|AAF28347.1| (AF217546) calmodulin-binding protein [Arabidopsis thaliana] >gi|6760430|gb|AAF28348.1| (AF217547) calmodulin-binding protein [Arabidopsis thaliana] Length = 1022 Score = 137 bits (342), Expect = 2e-31 Identities = 86/238 (36%), Positives = 131/238 (54%), Gaps = 16/238 (6%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGL------SIAKSPIEPPQGILLFGPPGTGKS 135 + +++ + W D+GG E K + +A+ + + PP GIL+FGPPG K+ Sbjct: 713 EVILEVPKVNWEDVGGQNEVKNQLMEAVEWPQKHQDAFKRIGTRPPSGILMFGPPGCSKT 772 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 L+A AVA+ F +VK +L SK+ GES K + +LF+ AR +PS+IF DE+DSL Sbjct: 773 LMARAVASEAKLNFLAVKGPELFSKWVGESEKAVRSLFAKARANAPSIIFFDEIDSLASI 832 Query: 196 RVSLDD---AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYV 250 R +D + R++ LL E+DG +R V V+ ATN P +D A+L R +YV Sbjct: 833 RGKENDGVSVSDRVMSQLLVELDGLHQRVG-VTVIAATNRPDKIDSALLRPGRFDRLLYV 891 Query: 251 PLPDVNSAVEIFKIHLRGI--HYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEE 306 P+ I KIHLR I D+ L LA ++ + Y+G +I+ + + A + LEE Sbjct: 892 GPPNETDREAILKIHLRKIPCSSDICLKELA--SITKGYTGADISLICREAAIAALEE 947 Score = 103 bits (254), Expect = 4e-21 Identities = 60/187 (32%), Positives = 101/187 (53%), Gaps = 9/187 (4%) Query: 95 IGGLREAKKLIAQAIGLSIAKSPIE-----PPQGILLFGPPGTGKSLLASAVANSLNATF 149 +GGL + ++ I S K+ + P +G+L+ GPPGTGK+ LA A F Sbjct: 387 LGGLSKEYAILRDIIDSSSIKNSLSGLGLRPTKGVLIHGPPGTGKTSLARTFARHSGVNF 446 Query: 150 FSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLT-MKRVSLDDAARRMIG 208 FSV +++S+Y GES K + +F A +P+ +FID++D++ ++ ++ ++RM+ Sbjct: 447 FSVNGPEIISQYLGESEKALDEVFRSASNATPAAVFIDDLDAIAPARKEGGEELSQRMVA 506 Query: 209 TLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHL 266 TLL MDG R D V+V+ ATN P ++ A+ RL I + P +I + L Sbjct: 507 TLLNLMDGI-SRTDGVVVIAATNRPDSIEPALRRPGRLDREIEIGAPSSTQRSDILHVIL 565 Query: 267 RGIHYDV 273 G+ + + Sbjct: 566 CGMRHSL 572 >pir||T51257 calmodulin-binding protein - Arabidopsis thaliana >gi|9662988|emb|CAC00732.1| (AL390921) calmodulin-binding protein [Arabidopsis thaliana] Length = 1022 Score = 137 bits (342), Expect = 2e-31 Identities = 86/238 (36%), Positives = 131/238 (54%), Gaps = 16/238 (6%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGL------SIAKSPIEPPQGILLFGPPGTGKS 135 + +++ + W D+GG E K + +A+ + + PP GIL+FGPPG K+ Sbjct: 713 EVILEVPKVNWEDVGGQNEVKNQLMEAVEWPQKHQDAFKRIGTRPPSGILMFGPPGCSKT 772 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 L+A AVA+ F +VK +L SK+ GES K + +LF+ AR +PS+IF DE+DSL Sbjct: 773 LMARAVASEAKLNFLAVKGPELFSKWVGESEKAVRSLFAKARANAPSIIFFDEIDSLASI 832 Query: 196 RVSLDD---AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYV 250 R +D + R++ LL E+DG +R V V+ ATN P +D A+L R +YV Sbjct: 833 RGKENDGVSVSDRVMSQLLVELDGLHQRVG-VTVIAATNRPDKIDSALLRPGRFDRLLYV 891 Query: 251 PLPDVNSAVEIFKIHLRGI--HYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEE 306 P+ I KIHLR I D+ L LA ++ + Y+G +I+ + + A + LEE Sbjct: 892 GPPNETDREAILKIHLRKIPCSSDICLKELA--SITKGYTGADISLICREAAIAALEE 947 Score = 109 bits (269), Expect = 6e-23 Identities = 63/187 (33%), Positives = 104/187 (54%), Gaps = 9/187 (4%) Query: 95 IGGLREAKKLIAQAIGLSIAKSPIE-----PPQGILLFGPPGTGKSLLASAVANSLNATF 149 +GGL + ++ I S K+ + P +G+L+ GPPGTGK+ LA A F Sbjct: 387 LGGLSKEYAILRDIIDSSSIKNSLSSLGLRPTKGVLIHGPPGTGKTSLARTFARHSGVNF 446 Query: 150 FSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLT-MKRVSLDDAARRMIG 208 FSV +++S+Y GES K + +F A +P+V+FID++D++ ++ ++ ++RM+ Sbjct: 447 FSVNGPEIISQYLGESEKALDEVFRSASNATPAVVFIDDLDAIAPARKEGGEELSQRMVA 506 Query: 209 TLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHL 266 TLL MDG R D V+V+ ATN P ++ A+ RL I + +P +I I L Sbjct: 507 TLLNLMDGI-SRTDGVVVIAATNRPDSIEPALRRPGRLDREIEIGVPSSTQRSDILHIIL 565 Query: 267 RGIHYDV 273 RG+ + + Sbjct: 566 RGMRHSL 572 >gb|AAF05624.1| (AF059715) cell survival CED-4-interacting protein MAC-1 [Caenorhabditis elegans] Length = 813 Score = 137 bits (341), Expect = 2e-31 Identities = 93/289 (32%), Positives = 149/289 (51%), Gaps = 28/289 (9%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSPIEP-------PQGILLFGPPGTGKSLLASAVA 142 ++W+DIG L E +K + +I I ++ PQGILL GPPG GK+LLA AVA Sbjct: 530 VSWDDIGALVEVRKQLEWSILYPIKRADDFAALGIDCRPQGILLCGPPGCGKTLLAKAVA 589 Query: 143 NSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDA 202 N FFSVK +LL+ Y GES + + +F AR P VIF DE+D+L KR + + Sbjct: 590 NETGMNFFSVKGPELLNMYVGESERAVRTVFQRARDSQPCVIFFDEIDALVPKRSHGESS 649 Query: 203 -ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAV 259 R++ LL EMDG E + KV ++ ATN P +D A+L RL ++V P V V Sbjct: 650 GGARLVNQLLTEMDGV-EGRQKVFLIGATNRPDIVDAAILRPGRLDKILFVDFPSVEDRV 708 Query: 260 EIFKIHLRG-----IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDP 314 +I + + + D+ +A+ ++G ++A + ++ L+ Sbjct: 709 DILRKSTKNGTRPMLGEDIDFHEIAQLPELAGFTGADLAVFIHELSLLALQ--------- 759 Query: 315 LRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEFAI 363 + + D + + + + F+ A +RI+ +T++D KKYE K + + Sbjct: 760 ---ARVLENDESVKGVGMRHFREAASRIRPSVTEADRKKYEHMKKIYGL 805 Score = 74.9 bits (181), Expect = 1e-12 Identities = 62/235 (26%), Positives = 112/235 (47%), Gaps = 43/235 (18%) Query: 86 KRSTITWNDIGGL-REAKKLIAQAIGLSIAKS----PIEPPQGILLFGPPGTGKSLLASA 140 + S + + IGG R+ ++ A+ L K+ ++PP+G ++ GPPG GK++ A A Sbjct: 199 RESHVKFEHIGGADRQFLEVCRLAMHLKRPKTFATLGVDPPRGFIVHGPPGCGKTMFAQA 258 Query: 141 VANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD 200 VA L + A++L+S GE+ + I LF A+Q SP ++ +D++D++ +R + Sbjct: 259 VAGELAIPMLQLAATELVSGVSGETEEKIRRLFDTAKQNSPCILILDDIDAIAPRRETAQ 318 Query: 201 -DAARRMIGTLLAEMDGF------KERKDK----------------------VIVLTATN 231 + RR++ L + +D K KD+ V+V+ T+ Sbjct: 319 REMERRVVSQLCSSLDELVLPPREKPLKDQLTFGDDGSVAIIGDSPTAAGAGVLVIGTTS 378 Query: 232 APWDLDEAM--LSRLPIRIYVPLPDVNSAVEIF----KIHLRGIHYDVPLSRLAK 280 P +D + R I + +PD + +I K++L G DV L ++AK Sbjct: 379 RPDAVDGRLRRTGRFQNEISLGIPDETAREKILEKICKVNLAG---DVTLKQIAK 430 >gb|AAG29874.1| (AF313486) valosin-containing protein [Homo sapiens] Length = 305 Score = 136 bits (340), Expect = 3e-31 Identities = 78/198 (39%), Positives = 117/198 (58%), Gaps = 13/198 (6%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKS 135 + +++ +TW DIGGL + K+ + + + + K + P +G+L +GPPG GK+ Sbjct: 94 ETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKT 153 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 LLA A+AN A F S+K +LL+ +FGES + +F ARQ +P V+F DE+DS+ Sbjct: 154 LLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKA 213 Query: 196 R-VSLDD---AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIY 249 R ++ D AA R+I +L EMDG +K+ V ++ ATN P +D A+L R IY Sbjct: 214 RGGNIGDGGGAADRVINQILTEMDGMSTKKN-VFIIGATNRPDIIDPAILRPGRPDQLIY 272 Query: 250 VPLPDVNSAVEIFKIHLR 267 +PLPD S V I K +LR Sbjct: 273 IPLPDEKSRVAILKANLR 290 >emb|CAB60418.1| (AL117203) contains similarity to Pfam domain: PF00004 (ATPases associated with various cellular activities (AAA)), Score=524.3, E-value=2.9e-154, N=2~cDNA EST yk185f2.3 comes from this gene~cDNA EST yk185f2.5 comes from this gene~cDNA EST yk269c8.3 co> Length = 757 Score = 136 bits (340), Expect = 3e-31 Identities = 92/289 (31%), Positives = 150/289 (51%), Gaps = 28/289 (9%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSPIEP-------PQGILLFGPPGTGKSLLASAVA 142 ++W+DIG L E +K + +I I ++ PQGILL GPPG GK+LLA AVA Sbjct: 474 VSWDDIGALVEVRKQLEWSILYPIKRADDFAALGIDCRPQGILLCGPPGCGKTLLAKAVA 533 Query: 143 NSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDA 202 N F SVK +LL+ Y GES + + +F AR P VIF DE+D+L KR + + Sbjct: 534 NETGMNFISVKGPELLNMYVGESERAVRTVFQRARDSQPCVIFFDEIDALVPKRSHGESS 593 Query: 203 -ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAV 259 R++ LL EMDG E + KV ++ ATN P +D A+L RL ++V P V V Sbjct: 594 GGARLVNQLLTEMDGV-EGRQKVFLIGATNRPDIVDAAILRPGRLDKILFVDFPSVEDRV 652 Query: 260 EIFKIHLRG-----IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDP 314 +I + + + D+ +A+ ++G ++A ++ +++ L+ Sbjct: 653 DILRKSTKNGTRPMLGEDIDFHEIAQLPELAGFTGADLAALIHESSLLALQ--------- 703 Query: 315 LRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEFAI 363 + + D + + + + F+ A +RI+ +T++D KKYE K + + Sbjct: 704 ---ARVLENDESVKGVGMRHFREAASRIRPSVTEADRKKYEHMKKIYGL 749 Score = 75.3 bits (182), Expect = 1e-12 Identities = 62/235 (26%), Positives = 112/235 (47%), Gaps = 43/235 (18%) Query: 86 KRSTITWNDIGGL-REAKKLIAQAIGLSIAKS----PIEPPQGILLFGPPGTGKSLLASA 140 + S + + IGG R+ ++ A+ L K+ ++PP+G ++ GPPG GK++ A A Sbjct: 143 RESHVKFEHIGGADRQFLEVCRLAMHLKRPKTFATLGVDPPRGFIVHGPPGCGKTMFAQA 202 Query: 141 VANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD 200 VA L + A++L+S GE+ + I LF A+Q SP ++ +D++D++ +R + Sbjct: 203 VAGELAIPMLQLAATELVSGVSGETEEKIRRLFDTAKQNSPCILILDDIDAIAPRRETAQ 262 Query: 201 -DAARRMIGTLLAEMDGF------KERKDK----------------------VIVLTATN 231 + RR++ L + +D K KD+ V+V+ T+ Sbjct: 263 REMERRVVSQLCSSLDELVLPPREKPLKDQLTFGDDGSVAIIGDSPTAAGAGVLVIGTTS 322 Query: 232 APWDLDEAM--LSRLPIRIYVPLPDVNSAVEIF----KIHLRGIHYDVPLSRLAK 280 P +D + R I + +PD + +I K++L G DV L ++AK Sbjct: 323 RPDAVDGGLRRAGRFENEISLGIPDETAREKILEKICKVNLAG---DVTLKQIAK 374 >pir||T31590 hypothetical protein Y48C3A.h - Caenorhabditis elegans Length = 856 Score = 136 bits (340), Expect = 3e-31 Identities = 92/289 (31%), Positives = 150/289 (51%), Gaps = 28/289 (9%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSPIEP-------PQGILLFGPPGTGKSLLASAVA 142 ++W+DIG L E +K + +I I ++ PQGILL GPPG GK+LLA AVA Sbjct: 573 VSWDDIGALVEVRKQLEWSILYPIKRADDFAALGIDCRPQGILLCGPPGCGKTLLAKAVA 632 Query: 143 NSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDA 202 N F SVK +LL+ Y GES + + +F AR P VIF DE+D+L KR + + Sbjct: 633 NETGMNFISVKGPELLNMYVGESERAVRTVFQRARDSQPCVIFFDEIDALVPKRSHGESS 692 Query: 203 -ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAV 259 R++ LL EMDG E + KV ++ ATN P +D A+L RL ++V P V V Sbjct: 693 GGARLVNQLLTEMDGV-EGRQKVFLIGATNRPDIVDAAILRPGRLDKILFVDFPSVEDRV 751 Query: 260 EIFKIHLRG-----IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDP 314 +I + + + D+ +A+ ++G ++A ++ +++ L+ Sbjct: 752 DILRKSTKNGTRPMLGEDIDFHEIAQLPELAGFTGADLAALIHESSLLALQ--------- 802 Query: 315 LRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEFAI 363 + + D + + + + F+ A +RI+ +T++D KKYE K + + Sbjct: 803 ---ARVLENDESVKGVGMRHFREAASRIRPSVTEADRKKYEHMKKIYGL 848 Score = 75.3 bits (182), Expect = 1e-12 Identities = 62/235 (26%), Positives = 112/235 (47%), Gaps = 43/235 (18%) Query: 86 KRSTITWNDIGGL-REAKKLIAQAIGLSIAKS----PIEPPQGILLFGPPGTGKSLLASA 140 + S + + IGG R+ ++ A+ L K+ ++PP+G ++ GPPG GK++ A A Sbjct: 242 RESHVKFEHIGGADRQFLEVCRLAMHLKRPKTFATLGVDPPRGFIVHGPPGCGKTMFAQA 301 Query: 141 VANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD 200 VA L + A++L+S GE+ + I LF A+Q SP ++ +D++D++ +R + Sbjct: 302 VAGELAIPMLQLAATELVSGVSGETEEKIRRLFDTAKQNSPCILILDDIDAIAPRRETAQ 361 Query: 201 -DAARRMIGTLLAEMDGF------KERKDK----------------------VIVLTATN 231 + RR++ L + +D K KD+ V+V+ T+ Sbjct: 362 REMERRVVSQLCSSLDELVLPPREKPLKDQLTFGDDGSVAIIGDSPTAAGAGVLVIGTTS 421 Query: 232 APWDLDEAM--LSRLPIRIYVPLPDVNSAVEIF----KIHLRGIHYDVPLSRLAK 280 P +D + R I + +PD + +I K++L G DV L ++AK Sbjct: 422 RPDAVDGGLRRAGRFENEISLGIPDETAREKILEKICKVNLAG---DVTLKQIAK 473 >sp|O32617|FTSH_HELFE CELL DIVISION PROTEIN FTSH HOMOLOG >gi|11278958|pir||T47267 cell cycle protein [imported] - Helicobacter felis >gi|2660540|emb|CAA05102.1| (AJ001932) cell cycle protein [Helicobacter felis] Length = 638 Score = 136 bits (339), Expect = 4e-31 Identities = 88/258 (34%), Positives = 136/258 (52%), Gaps = 18/258 (6%) Query: 60 WEEKAKNVRKRREGKNEYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGL-----S 112 W A ++K G K LI ++ + +ND+ G EAK+ + + + Sbjct: 141 WMFMASRMQKNMGGGIFGMGSSKKLINAEKPKVRFNDMAGNEEAKEEVVEIVDFLKYPDR 200 Query: 113 IAKSPIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISAL 172 A + P+G+LL GPPGTGK+LLA AVA + FFS+ S + + G + + L Sbjct: 201 YASLGAKIPKGVLLVGPPGTGKTLLAKAVAGEASVPFFSMGGSSFIEMFVGLGASRVRDL 260 Query: 173 FSLARQLSPSVIFIDEVDSLTMKR-----VSLDDAARRMIGTLLAEMDGFKERKDKVIVL 227 F +A++ +PS+IFIDE+D++ R +S +D + + LLAEMDGF VIVL Sbjct: 261 FDIAKKEAPSIIFIDEIDAIGKSRAAGGMISGNDEREQTLNQLLAEMDGFGSENAPVIVL 320 Query: 228 TATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHY--DVPLSRLAKEAV 283 ATN P LD A+L R ++ V PD VEI K+H++ + DV L +AK + Sbjct: 321 AATNRPEILDPALLRPGRFDRQVLVDKPDFKGRVEILKVHIKPVKLANDVDLQEIAK--L 378 Query: 284 KRLYSGREIANVVKLATM 301 +G ++AN++ A + Sbjct: 379 TAGLAGADLANIINEAAL 396 >pir||T40537 AAA family ATPase - fission yeast (Schizosaccharomyces pombe) >gi|3116137|emb|CAA18886.1| (AL023288) AAA family ATPase [Schizosaccharomyces pombe] Length = 809 Score = 136 bits (338), Expect = 5e-31 Identities = 86/286 (30%), Positives = 152/286 (53%), Gaps = 31/286 (10%) Query: 84 LIKRSTITWNDIGGLREAKKLIAQAI------GLSIAKSPIEPPQGILLFGPPGTGKSLL 137 +++ + W+DIGG E K+ + +++ G + ++ + PP+G+LL+GPPG K++ Sbjct: 539 MMESPNVHWSDIGGQEEVKQKLKESVEWPLTHGETFSRLGVRPPKGVLLYGPPGCSKTIT 598 Query: 138 ASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRV 197 A A+A F +VK +L K+ GES + + +F ARQ SPSVIF DE+D+LT R Sbjct: 599 AKAIATETGLNFIAVKGPELFDKFVGESERAVRQVFQKARQASPSVIFFDEIDALTANR- 657 Query: 198 SLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDV 255 D+++ R++ LL E+DG + ++ V+VL ATN P +D A++ RL +YV P+ Sbjct: 658 GEDNSSDRVVAALLNELDGIEALRN-VLVLAATNRPDMIDPALMRPGRLDRLLYVGPPNF 716 Query: 256 NSAVEIFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSD 313 + +I KI + + DV L +A++ SG E+ + + A + + E Sbjct: 717 EARKQIVKIQAEKMKFAEDVDLDLIAEKT--EGCSGAEVVALCQEAGLIAMHE------- 767 Query: 314 PLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAK 359 DL + + FK A+ ++ IT+ ++ Y +++ Sbjct: 768 ----------DLEAKEICQAHFKTALLALRKAITRDMLEYYASFSE 803 Score = 132 bits (329), Expect = 6e-30 Identities = 98/352 (27%), Positives = 174/352 (48%), Gaps = 33/352 (9%) Query: 2 YRLQLLQVQKCQEEFERALSLGHYDKARLIALRCAELLRKIASENLSLSHILLEEAKKWE 61 Y+++ + ++ E A+S D+ R+ A + + L L H E Sbjct: 203 YKVKEIHIRSPSNLIE-AISDMSLDEPRIYKFTAASSMEIETPDLLKLPH---------E 252 Query: 62 EKAKNVRKRREGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP---- 117 ++ ++ + + + FD S +T++ IGGL+ I + L Sbjct: 253 DRTQSAYNQGSEETQNFDG-----PPSAVTFSSIGGLQAQIAQIRDIVELPFQNPELFKF 307 Query: 118 --IEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSL 175 I PP+G+LL+GPPGTGK+++ AVA NA F++ ++ KY GE+ + +F Sbjct: 308 FNIMPPRGVLLYGPPGTGKTMVMRAVAAEANAQVFTIDGPSVVGKYLGETESRLRKIFED 367 Query: 176 ARQLSPSVIFIDEVDSLTMKRV-SLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPW 234 AR PS+IFIDE+D+L KR + +A R + TLL +DG KV+V+ ATN P Sbjct: 368 ARAHQPSIIFIDEIDALAPKRTEDVSEAESRAVATLLTLLDGM-ANAGKVVVIAATNRPN 426 Query: 235 DLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVK-RLYSGRE 291 +DEA+ RL I + +PD ++ ++I K+ L G+ ++ ++L A + Y G + Sbjct: 427 SIDEALRRPGRLEKEIEIGIPDKSARLDIIKLLLSGVPNEINDAQLEDLASRTHAYVGAD 486 Query: 292 IANVVKLATMKMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIK 343 +A VV+ A ++ ++ D G D+ + +DD ++A++ ++ Sbjct: 487 LAAVVREAALRAIKRTISLQKD------TSGLDI-FGAVQMDDLEFALSSVR 531 >gb|AAC44563.1| (U59452) HpFtsH [Helicobacter pylori] Length = 632 Score = 135 bits (337), Expect = 7e-31 Identities = 87/258 (33%), Positives = 135/258 (51%), Gaps = 18/258 (6%) Query: 60 WEEKAKNVRKRREGKNEYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGL-----S 112 W A ++K G K LI ++ + +ND+ G EAK+ + + + Sbjct: 135 WMFMANRMQKNMGGGIFGMGSAKKLINAEKPNVRFNDMAGNEEAKEEVVEIVDFLKYPER 194 Query: 113 IAKSPIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISAL 172 A + P+G+LL GPPGTGK+LLA AVA + FFS+ S + + G + + L Sbjct: 195 YANLGAKIPKGVLLVGPPGTGKTLLAKAVAGEAHVPFFSMGGSSFIEMFVGLGASRVRDL 254 Query: 173 FSLARQLSPSVIFIDEVDSLTMKR-----VSLDDAARRMIGTLLAEMDGFKERKDKVIVL 227 F A++ +PS+IFIDE+D++ R +S +D + + LLAEMDGF VIVL Sbjct: 255 FETAKKQAPSIIFIDEIDAIPKSRAAGGMISGNDEREQTLNQLLAEMDGFGSENAPVIVL 314 Query: 228 TATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHY--DVPLSRLAKEAV 283 ATN P LD A++ R ++ V PD N VEI K+ ++G+ DV +AK + Sbjct: 315 AATNRPEILDPALMRPGRFDRQVLVDKPDFNGRVEILKVDIKGVKLANDVNFEEVAK--L 372 Query: 284 KRLYSGREIANVVKLATM 301 +G ++AN++ A + Sbjct: 373 TAGLAGADLANIINEAAL 390 >pir||S51042 tat-binding protein homolog - malaria parasite (Plasmodium falciparum) Length = 435 Score = 134 bits (335), Expect = 1e-30 Identities = 91/243 (37%), Positives = 135/243 (55%), Gaps = 17/243 (6%) Query: 79 DKLKALIKRSTI---TWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFG 128 D L +L+K + T+ +GGL + K + + I L + K P I P+G+LL+G Sbjct: 162 DPLVSLMKVEKVPDSTYEMVGGLDQQVKEVKEVIELPV-KHPEIFESLGISQPKGVLLYG 220 Query: 129 PPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDE 188 PPGTGK+LLA AVA+ + TF V S+L+ KY GE S+++ LF +AR+ +PS+IF+DE Sbjct: 221 PPGTGKTLLARAVAHHTDCTFIRVSGSELVQKYIGEGSRMVRELFVMAREHAPSIIFMDE 280 Query: 189 VDSLTMKRVS---LDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SR 243 +DS+ +R+ D +R + LL ++DGF E + V+ TN LDEA+L R Sbjct: 281 IDSIGSQRIEGEHGDSEVQRTMMELLNQLDGF-ESTQNIKVIMCTNRIDILDEALLRPGR 339 Query: 244 LPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKM 303 + +I P P+V + +EI KIH R I+ + L SG E+ V A M Sbjct: 340 IDRKIEFPNPNVEARMEILKIHSRKINLMRGIDMLKIATHMNNCSGAEVKAVCTEAGMFA 399 Query: 304 LEE 306 L E Sbjct: 400 LRE 402 >gb|AAF27916.1|AF220199_1 (AF220199) 26S proteasome regulatory subunit 8 [Pinus taeda] Length = 433 Score = 134 bits (335), Expect = 1e-30 Identities = 98/283 (34%), Positives = 151/283 (52%), Gaps = 39/283 (13%) Query: 91 TWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFGPPGTGKSLLASAVAN 143 T++ IGGL + K I + I L I K P I P+G+LL+GPPGTGK+LLA AVA+ Sbjct: 173 TYDMIGGLDQQIKEIKEVIELPI-KHPELFESLGIAQPKGVLLYGPPGTGKTLLARAVAH 231 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL---- 199 + TF V S+L+ KY GE S+++ LF +AR+ +PS+IF+DE+DS+ R+ Sbjct: 232 HTDCTFIRVSGSELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSARMESGTGN 291 Query: 200 -DDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVN 256 D +R + LL ++DGF E +K+ VL ATN LD+A+L R+ +I P P+ Sbjct: 292 GDSEVQRTMLELLNQLDGF-EASNKIKVLMATNRIDILDQALLRPGRIDRKIEFPNPNEE 350 Query: 257 SAVEIFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDP 314 S +I KIH R ++ + L ++A++ SG E+ V A M L E Sbjct: 351 SRFDILKIHSRKMNLMRGIDLKKIAEKMSGA--SGAELKAVCTEAGMFALRERRVH---- 404 Query: 315 LRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERW 357 +T +DF+ A+A++ T+ ++ + W Sbjct: 405 ---------------VTQEDFEMAVAKVMKKETEKNMSLRKLW 432 >dbj|BAB17626.1| (AB033537) 26S proteasome regulatory particle triple-A ATPase subunit6 [Oryza sativa] Length = 424 Score = 134 bits (335), Expect = 1e-30 Identities = 98/283 (34%), Positives = 152/283 (53%), Gaps = 39/283 (13%) Query: 91 TWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFGPPGTGKSLLASAVAN 143 T++ IGGL + K I + I L I K P I P+G+LL+GPPGTGK+LLA AVA+ Sbjct: 164 TYDMIGGLDQQIKEIKEVIELPI-KHPELFESLGIAQPKGVLLYGPPGTGKTLLARAVAH 222 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL---- 199 + TF V S+L+ KY GE S+++ LF +AR+ +PS+IF+DE+DS+ R+ Sbjct: 223 HTDCTFIRVSGSELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSARMESGTGN 282 Query: 200 -DDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVN 256 D +R + LL ++DGF E +K+ VL ATN LD+A+L R+ +I P P+ + Sbjct: 283 GDSEVQRTMLELLNQLDGF-EASNKIKVLMATNRIDILDQALLRPGRIDRKIEFPNPNED 341 Query: 257 SAVEIFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDP 314 S +I KIH R ++ + L ++A++ SG E+ V A M L E Sbjct: 342 SRFDILKIHSRKMNLMRGIDLKKIAEK--MNGASGAELKAVCTEAGMFALRERRVH---- 395 Query: 315 LRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERW 357 +T +DF+ A+A++ T+ ++ + W Sbjct: 396 ---------------VTQEDFEMAVAKVMKKDTEKNMSLRKLW 423 >gb|AAB70457.1| (U68140) nuclear VCP-like protein NVLp.2 [Homo sapiens] Length = 856 Score = 134 bits (334), Expect = 1e-30 Identities = 96/293 (32%), Positives = 152/293 (51%), Gaps = 27/293 (9%) Query: 80 KLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFGPPGT 132 K + + +TW DIG L + ++ + AI L+ ++P + P G+LL GPPG Sbjct: 568 KREGFVTVPNVTWADIGALEDIREELTMAI-LAPVRNPDQFKALGLVTPAGVLLAGPPGC 626 Query: 133 GKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSL 192 GK+LLA AVAN F SVK +LL+ Y GES + + +F A+ +P VIF DEVD+L Sbjct: 627 GKTLLAKAVANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDAL 686 Query: 193 TMKRVSLDDAAR-RMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIY 249 +R + A R++ LL EMDG E + +V ++ ATN P +D A+L RL ++ Sbjct: 687 CPRRSDRETGASVRVVNQLLTEMDGL-EARQQVFIMAATNRPDIIDPAILRPGRLDKTLF 745 Query: 250 VPLPDVNSAVEIFKIHLRG-----IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKML 304 V LP + I K + + DV L +A + Y+G +++ +V+ A++ L Sbjct: 746 VGLPPPADRLAILKTITKNGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICAL 805 Query: 305 -EEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYER 356 +EM + S G + ++ F+ A +++S I+K D YER Sbjct: 806 RQEMARQKS---------GNEKGELKVSHKHFEEAFKKVRSSISKKDQIMYER 849 Score = 103 bits (255), Expect = 3e-21 Identities = 76/234 (32%), Positives = 121/234 (51%), Gaps = 23/234 (9%) Query: 53 LLEEAKKWEEKAKNV--RKRREGKNEYFDKLKALIKR-----------STITWNDIGG-- 97 LLE K + K KN ++++E E +++A++++ S + + D+GG Sbjct: 212 LLESDMKRKGKLKNKGSKRKKEDLQEVDGEIEAVLQKKAKARGLEFQISNVKFEDVGGND 271 Query: 98 --LREAKKLIAQAIGLSIAKS-PIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKA 154 L+E K++ + + PP+G+LL GPPG GK+LLA A+A L+ V A Sbjct: 272 MTLKEVCKMLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAGELDLPILKVAA 331 Query: 155 SDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR-VSLDDAARRMIGTLLAE 213 +++S GES + + LF A +P +IFIDE+D++T KR V+ D RR++ LL Sbjct: 332 PEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVASKDMERRIVAQLLTC 391 Query: 214 MDGFKE--RKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSAVEIFK 263 MD +V+V+ ATN P LD A+ R I + +PD S I + Sbjct: 392 MDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEASRERILQ 445 >gi|4505483 nuclear VCP-like; Nuclear valosin-containing protein-like [Homo sapiens] >gi|11448052|ref|XP_001975.1| nuclear VCP-like [Homo sapiens] >gi|2406580|gb|AAB70460.1| (U78772) nuclear VCP-like protein NVLp.1 [Homo sapiens] Length = 750 Score = 134 bits (334), Expect = 1e-30 Identities = 96/293 (32%), Positives = 152/293 (51%), Gaps = 27/293 (9%) Query: 80 KLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFGPPGT 132 K + + +TW DIG L + ++ + AI L+ ++P + P G+LL GPPG Sbjct: 462 KREGFVTVPNVTWADIGALEDIREELTMAI-LAPVRNPDQFKALGLVTPAGVLLAGPPGC 520 Query: 133 GKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSL 192 GK+LLA AVAN F SVK +LL+ Y GES + + +F A+ +P VIF DEVD+L Sbjct: 521 GKTLLAKAVANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDAL 580 Query: 193 TMKRVSLDDAAR-RMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIY 249 +R + A R++ LL EMDG E + +V ++ ATN P +D A+L RL ++ Sbjct: 581 CPRRSDRETGASVRVVNQLLTEMDGL-EARQQVFIMAATNRPDIIDPAILRPGRLDKTLF 639 Query: 250 VPLPDVNSAVEIFKIHLRG-----IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKML 304 V LP + I K + + DV L +A + Y+G +++ +V+ A++ L Sbjct: 640 VGLPPPADRLAILKTITKNGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICAL 699 Query: 305 -EEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYER 356 +EM + S G + ++ F+ A +++S I+K D YER Sbjct: 700 RQEMARQKS---------GNEKGELKVSHKHFEEAFKKVRSSISKKDQIMYER 743 Score = 103 bits (255), Expect = 3e-21 Identities = 76/234 (32%), Positives = 121/234 (51%), Gaps = 23/234 (9%) Query: 53 LLEEAKKWEEKAKNV--RKRREGKNEYFDKLKALIKR-----------STITWNDIGG-- 97 LLE K + K KN ++++E E +++A++++ S + + D+GG Sbjct: 106 LLESDMKRKGKLKNKGSKRKKEDLQEVDGEIEAVLQKKAKARGLEFQISNVKFEDVGGND 165 Query: 98 --LREAKKLIAQAIGLSIAKS-PIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKA 154 L+E K++ + + PP+G+LL GPPG GK+LLA A+A L+ V A Sbjct: 166 MTLKEVCKMLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAGELDLPILKVAA 225 Query: 155 SDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR-VSLDDAARRMIGTLLAE 213 +++S GES + + LF A +P +IFIDE+D++T KR V+ D RR++ LL Sbjct: 226 PEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVASKDMERRIVAQLLTC 285 Query: 214 MDGFKE--RKDKVIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSAVEIFK 263 MD +V+V+ ATN P LD A+ R I + +PD S I + Sbjct: 286 MDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEASRERILQ 339 >gb|AAF22526.1|AF123395_1 (AF123395) 26S proteasome AAA-ATPase subunit RPT6a [Arabidopsis thaliana] Length = 405 Score = 134 bits (334), Expect = 1e-30 Identities = 98/283 (34%), Positives = 151/283 (52%), Gaps = 39/283 (13%) Query: 91 TWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFGPPGTGKSLLASAVAN 143 T++ IGGL + K I + I L I K P I P+G+LL+GPPGTGK+LLA AVA+ Sbjct: 145 TYDMIGGLDQQIKEIKEVIELPI-KHPELFESLGIAQPKGVLLYGPPGTGKTLLARAVAH 203 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL---- 199 + TF V S+L+ KY GE S+++ LF +AR+ +PS+IF+DE+DS+ R+ Sbjct: 204 HTDCTFIRVSGSELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSARMESGSGN 263 Query: 200 -DDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVN 256 D +R + LL ++DGF E +K+ VL ATN LD+A+L R+ +I P P+ Sbjct: 264 GDSEVQRTMLELLNQLDGF-EASNKIKVLMATNRIDILDQALLRPGRIDRKIEFPNPNEE 322 Query: 257 SAVEIFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDP 314 S +I KIH R ++ + L ++A++ SG E+ V A M L E Sbjct: 323 SRFDILKIHSRKMNLMRGIDLKKIAEK--MNGASGAELKAVCTEAGMFALRERRVH---- 376 Query: 315 LRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERW 357 +T +DF+ A+A++ T+ ++ + W Sbjct: 377 ---------------VTQEDFEMAVAKVMKKDTEKNMSLRKLW 404 >gi|6323429 homology to the CDC48 gene product; Afg2p [Saccharomyces cerevisiae] >gi|416590|sp|P32794|AFG2_YEAST AFG2 PROTEIN >gi|481664|pir||S39110 valosin-containing protein homolog AFG2 - yeast (Saccharomyces cerevisiae) >gi|295573|gb|AAC37367.1| (L14615) AFG2 [Saccharomyces cerevisiae] >gi|625113|gb|AAB82355.1| (U19729) Afg2p [Saccharomyces cerevisiae] Length = 780 Score = 134 bits (333), Expect = 2e-30 Identities = 96/281 (34%), Positives = 143/281 (50%), Gaps = 32/281 (11%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSI------AKSPIEPPQGILLFGPPGTGKSLLASAVAN 143 + W+DIGG E K + + I L + A+ I P+G+LL+GPPG K+L A A+A Sbjct: 513 VYWSDIGGQEELKTKMKEMIQLPLEASETFARLGISAPKGVLLYGPPGCSKTLTAKALAT 572 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR-VSLDDA 202 F +VK ++ +KY GES + I +F AR +PS+IF DE+D+L+ R S A Sbjct: 573 ESGINFLAVKGPEIFNKYVGESERAIREIFRKARSAAPSIIFFDEIDALSPDRDGSSTSA 632 Query: 203 ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVE 260 A ++ +LL E+DG +E K V+++ ATN P ++D A+L RL IYV PDVN+ +E Sbjct: 633 ANHVLTSLLNEIDGVEELKG-VVIVAATNRPDEIDAALLRPGRLDRHIYVGPPDVNARLE 691 Query: 261 IFKIHLRGIHYD---VPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRV 317 I K + + + V L LA YSG E+ + + A + + E Sbjct: 692 ILKKCTKKFNTEESGVDLHELADRT--EGYSGAEVVLLCQEAGLAAIME----------- 738 Query: 318 STLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWA 358 DL + L F+ A I IT + YE +A Sbjct: 739 ------DLDVAKVELRHFEKAFKGIARGITPEMLSYYEEFA 773 Score = 116 bits (287), Expect = 5e-25 Identities = 81/270 (30%), Positives = 138/270 (51%), Gaps = 28/270 (10%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVAN 143 +++ +GGL + + + AI + + + + PP+GILL GPPGTGK++L VAN Sbjct: 242 LSYAAVGGLDKEIESLKSAIEIPLHQPTLFSSFGVSPPRGILLHGPPGTGKTMLLRVVAN 301 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD--D 201 + NA ++ ++SKY GE+ + +F+ AR+ PS+IFIDE+DS+ R + D + Sbjct: 302 TSNAHVLTINGPSIVSKYLGETEAALRDIFNEARKYQPSIIFIDEIDSIAPNRANDDSGE 361 Query: 202 AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAV 259 R++ TLL MDG KV+V+ ATN P +D A+ R + + +PDV++ Sbjct: 362 VESRVVATLLTLMDGM-GAAGKVVVIAATNRPNSVDPALRRPGRFDQEVEIGIPDVDARF 420 Query: 260 EIFKIHLRGIHYDVPLSRLAKEAVKRL------YSGREIANVVKLATMKMLEEMNPELSD 313 +I + D + L EA+K + Y G ++ + + + MK ++ Sbjct: 421 DILTKQFSRMSSDRHV--LDSEAIKYIASKTHGYVGADLTALCRESVMKTIQR------- 471 Query: 314 PLRVSTLKGRDLTTRPLTLDDFKYAMARIK 343 + T D + +TL D + AM I+ Sbjct: 472 --GLGTDANIDKFSLKVTLKDVESAMVDIR 499 >pir||T49647 MSP1 related protein [imported] - Neurospora crassa >gi|7801053|emb|CAB91448.1| (AL355933) MSP1 related protein [Neurospora crassa] Length = 1104 Score = 134 bits (333), Expect = 2e-30 Identities = 98/265 (36%), Positives = 136/265 (50%), Gaps = 19/265 (7%) Query: 57 AKKWEEKAKNVRKRREGKNEYFDKLKA-LIKRSTI--TWNDIGGLREAKKLIAQAIGLSI 113 + W + +++ KL A L+ I T++DI E K+ + LS+ Sbjct: 722 SSSWASSQSQTASDNKDYDQHEKKLLAGLVNAKDIHTTFDDIIVPAETKESLIGLTSLSL 781 Query: 114 AKSPI--------EPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGES 165 + E G LL+GPPGTGK+LLA AVA A V A+ + + G+S Sbjct: 782 QRPDAFAYGVLKTERIPGCLLYGPPGTGKTLLAKAVAKESGANMLEVSAASINDMWLGQS 841 Query: 166 SKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD--DAARRMIGTLLAEMDGFKERKDK 223 K + ALFSLAR+LSP VIF+DE D+L R + A R I L E DG + + Sbjct: 842 EKNVRALFSLARKLSPMVIFLDEADALLGARHNNPGRTAHRETITQFLREWDGLSDM--R 899 Query: 224 VIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKE 281 ++ ATN P+DLDEA+L RLP +I V LP V +I K+ LR + DV L LAKE Sbjct: 900 AFIMVATNRPFDLDEAVLRRLPRKILVDLPLVAERAKILKVMLREEQLAPDVDLDALAKE 959 Query: 282 AVKRLYSGREIANVVKLATMKMLEE 306 LYSG ++ N+ A M+ + E Sbjct: 960 T--DLYSGSDLKNLCVSAAMEAVRE 982 >gb|AAK42941.1| AAA family ATPase [Sulfolobus solfataricus] Length = 585 Score = 133 bits (332), Expect = 3e-30 Identities = 92/294 (31%), Positives = 157/294 (53%), Gaps = 28/294 (9%) Query: 78 FDKLKALIKR---STITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFG 128 +++ K +IK I+WND+G L E K++I ++I L I K I P +GILL+G Sbjct: 307 YERSKLIIKTYGIPNISWNDLGDLEEVKRIIRESIVLPITNKEFAEKLGIYPVKGILLYG 366 Query: 129 PPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDE 188 PPGTGK+ +A A+AN L F + ++ ++ K+I+ F +A +P++IFIDE Sbjct: 367 PPGTGKTSIAKALANDLRFNFIELSGEEVSGAGPLDAPKIIAEKFYIALDNAPAIIFIDE 426 Query: 189 VDSLTMKRVSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPI 246 +D + R++ + R + LL +MDG +E + VIV+ ATN PWDLD A+L R Sbjct: 427 IDMIARNRMT--NEWRNALTELLRQMDGLREIHN-VIVVGATNRPWDLDPAILRAGRFDK 483 Query: 247 RIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEE 306 IYVP PD + +I ++ ++ + + + E + Y+ ++ VV+ +L+E Sbjct: 484 IIYVPPPDKDGREKILQVLIKDLIINRNIISKVAELTEN-YTPADLKLVVEEVKRNLLKE 542 Query: 307 MNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKE 360 + +S LR + L+DF + R+K+ + + + YE++ E Sbjct: 543 AS--ISGNLRTE-----------VKLEDFMDVLKRVKASLDRQTLIMYEKFGFE 583 Score = 129 bits (322), Expect = 4e-29 Identities = 91/284 (32%), Positives = 147/284 (51%), Gaps = 37/284 (13%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPIEP-PQGILLFGPPGTGKSLLASA 140 K I I W+++ L++ K + + IAK E G++LFGPPGTGK+ +A A Sbjct: 57 KPKIHIPNIRWDEVYDLKDVKMRLEE-----IAKIVQEGRAYGVILFGPPGTGKTTIAKA 111 Query: 141 VANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVS-L 199 +AN L +F ++ S +LSK++GES L+ + F +P+V+FIDE+DSL M R S L Sbjct: 112 LANKLGWAYFELRPSKILSKWYGESELLLDSFFDQVEINTPAVVFIDELDSLAMSRQSDL 171 Query: 200 DDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNS 257 + R++ +L + ++ +VI++ ATN P ++DEA L R IYV LPD S Sbjct: 172 HEVTHRLVNIMLMRLQDLHDKNLRVIIIGATNVPQEIDEAFLRPGRFDEVIYVALPDEKS 231 Query: 258 AVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRV 317 EI+K +++ D+ S LAK++ + +S +I NV K++ + N Sbjct: 232 REEIWKGYIK--REDIDYSLLAKKSER--FSPADIKNVAD----KVISKNN--------- 274 Query: 318 STLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 L +DF + K I S + K+E A+++ Sbjct: 275 -----------SLKTEDFLREIENYKPSIQLSTIIKFENIARKY 307 >gb|AAF53216.1| (AE003637) CG5776 gene product [Drosophila melanogaster] Length = 799 Score = 133 bits (332), Expect = 3e-30 Identities = 84/241 (34%), Positives = 134/241 (54%), Gaps = 19/241 (7%) Query: 82 KALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKS 135 + LI+ + W+DIGG E + + QAI + + I+PP+GIL+FGPPG K+ Sbjct: 524 EVLIECPNVQWSDIGGQSELRLAMQQAIEWPLLHADKFQRLGIKPPRGILMFGPPGCSKT 583 Query: 136 LLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK 195 ++A A+A F S+K +L S + GES + + +F ARQ++P+++F DE+D++ + Sbjct: 584 MIAKALATESKLNFLSIKGPELFSMWVGESERAVREVFRKARQVAPAIVFFDEIDAIGGE 643 Query: 196 RVSLDDAA------RRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIR 247 R D ++ R++ LL E+DG E V ++ ATN P +D+A+L R+ Sbjct: 644 RSEGDGSSSGSSVKERVLTQLLTELDGV-EALQNVTIVAATNRPDMIDKALLRPGRIDRI 702 Query: 248 IYVPLPDVNSAVEIFKIHLRG--IHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLE 305 +YV LP + EI KI LR I DV + +L + + YSG EI V A ++ LE Sbjct: 703 LYVGLPQCEARREILKIKLRAMPISNDVDMEKLVQ--LTEGYSGAEIQAVCHEAALRALE 760 Query: 306 E 306 + Sbjct: 761 Q 761 >gb|AAF58864.1| (AE003831) TER94 gene product [alt 1] [Drosophila melanogaster] Length = 297 Score = 133 bits (331), Expect = 3e-30 Identities = 90/257 (35%), Positives = 140/257 (54%), Gaps = 18/257 (7%) Query: 118 IEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLAR 177 ++P +G+L +GPPG GK+LLA A+AN A F SVK +LL+ +FGES + +F AR Sbjct: 1 MQPSRGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDKAR 60 Query: 178 QLSPSVIFIDEVDSLTMKR----VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAP 233 +P V+F DE+DS+ R AA R+I +L EMDG +K+ V ++ ATN P Sbjct: 61 SAAPCVLFFDELDSIAKARGGNVGDAGGAADRVINQILTEMDGMGAKKN-VFIIGATNRP 119 Query: 234 WDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSG 289 +D A+L RL IY+PLPD S I K +LR + +V L+ +AK V + +SG Sbjct: 120 DIIDPAILRPGRLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAK--VTQGFSG 177 Query: 290 REIANV----VKLATMKMLE---EMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARI 342 ++ + KLA + +E E ++ + D +T F+ AM Sbjct: 178 ADLTEICQRACKLAIRQAIEAEIRREKERAENQNSAMDMDEDDPVPEITSAHFEEAMKFA 237 Query: 343 KSPITKSDVKKYERWAK 359 + ++ +D++KYE +A+ Sbjct: 238 RRSVSDNDIRKYEMFAQ 254 >sp|Q9ZEA2|FTSH_RICPR CELL DIVISION PROTEIN FTSH HOMOLOG >gi|7446570|pir||C71712 cell division protein ftsH (ftsH) RP043 - Rickettsia prowazekii >gi|3860613|emb|CAA14514.1| (AJ235270) CELL DIVISION PROTEIN FTSH (ftsH) [Rickettsia prowazekii] Length = 637 Score = 132 bits (330), Expect = 4e-30 Identities = 85/244 (34%), Positives = 133/244 (53%), Gaps = 17/244 (6%) Query: 73 GKNEYFDKLKALI---KRSTITWNDIGGLREAKKLIAQAIGLSIAKSPIEP-----PQGI 124 GK F K KA + K IT+ D+ G+ EAK+ + + + S + P+G Sbjct: 132 GKAMGFGKSKARLLSDKGPKITFKDVAGIDEAKEELTEIVDFLRDPSKFQKLGGKIPKGC 191 Query: 125 LLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVI 184 LL GPPGTGK+LLA A+A N FFS+ SD + + G + + +F ++ +P +I Sbjct: 192 LLIGPPGTGKTLLAKAIAGEANVPFFSISGSDFVEMFVGVGASRVRDMFEQGKRNAPCII 251 Query: 185 FIDEVDSLTMKR-VSL---DDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM 240 FIDE+D++ R + + +D + + +L EMDGF E + V+++ ATN P LD A+ Sbjct: 252 FIDEIDAVGRHRGIGMGGGNDEREQTLNQMLVEMDGF-EANEGVVIIAATNRPDVLDRAL 310 Query: 241 L--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHYD-VPLSRLAKEAVKRLYSGREIANVVK 297 L R +I V PD+N +I K+HL+ I Y+ L+R+ +SG E+AN+V Sbjct: 311 LRPGRFDRQIAVANPDINGREQILKVHLKKIKYNSTVLARIIARGTPG-FSGAELANLVN 369 Query: 298 LATM 301 A + Sbjct: 370 EAAL 373 >gi|8922407 fidgetin; fidgetin; hypothetical protein FLJ10405 [Homo sapiens] >gi|7022415|dbj|BAA91590.1| (AK001267) unnamed protein product [Homo sapiens] Length = 639 Score = 132 bits (330), Expect = 4e-30 Identities = 89/281 (31%), Positives = 148/281 (51%), Gaps = 17/281 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSPIEP-----PQGILLFGPPGTGKSLLASAVANS 144 + WNDI GL K +I + + + +S P+ ILLFGP GTGK+LL +A+ Sbjct: 363 VDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQ 422 Query: 145 LNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDA-A 203 L ATFF + S L++K+ GE+ K+I A F +AR PSVIF+ ++D L +V+ + + Sbjct: 423 LGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHSPV 482 Query: 204 RRMIGTLLAEMDG-FKERKDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIF 262 RM L ++D +D+++V+ AT+ P ++DE++ R+ +PLPD + +I Sbjct: 483 SRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQII 542 Query: 263 KIHLRGIHYDVPLSRLAKEAVKRL--YSGREIANVVKLATMKMLEEMNPELSDPLRVSTL 320 L +Y + A V+R +SG ++A++ + A + L M + S L Sbjct: 543 VQLLSQHNYCLNDKEFAL-LVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQL 601 Query: 321 KGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 RP+T DF+ A +I+ I++ ++ Y W K F Sbjct: 602 -------RPVTYQDFENAFCKIQPSISQKELDMYVEWNKMF 635 >gb|AAF52903.1| (AE003628) CG5395 gene product [Drosophila melanogaster] Length = 369 Score = 132 bits (330), Expect = 4e-30 Identities = 93/314 (29%), Positives = 161/314 (50%), Gaps = 21/314 (6%) Query: 44 SENLSLSHILLEEAKKWEEKAKNVRKRREGKNEYFDKLKALI---KRSTITWNDIGGLRE 100 S+N + +L EE K + + + R + ++Y + + + T++W DI GL Sbjct: 45 SKNKKKAKVLAEEQLKRLAEQEGFKLRGQEFSDYELMIASHLVVPADITVSWADIAGLDS 104 Query: 101 AKKLIAQAIGLSIAKSPI-------EPPQGILLFGPPGTGKSLLASAVANSLNATFFSVK 153 + + +++ L I + + P+G+LL GPPG GK+L+A A A F ++ Sbjct: 105 VIQELRESVVLPIQHKDLFKHSKLWQAPKGVLLHGPPGCGKTLIAKATAKEAGMRFINLD 164 Query: 154 ASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDAARRMIGT-LLA 212 + L K++GES KL SA+FSLA ++ P +IFIDE+DS R D A M+ T + Sbjct: 165 VAILTDKWYGESQKLTSAVFSLASRIEPCIIFIDEIDSFLRSRNMNDHEATAMMKTQFMM 224 Query: 213 EMDGFKERKDK-VIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRG--I 269 DG + VIV+ ATN P DLD+A++ R+P + ++ LP +I K+ L+ + Sbjct: 225 LWDGLSTNANSTVIVMGATNRPQDLDKAIVRRMPAQFHIGLPSETQRKDILKLILQSEEV 284 Query: 270 HYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVSTLKGRDLTTRP 329 DV L+RL+K + +SG ++ + + A++ + ++ R + D Sbjct: 285 SQDVDLNRLSK--LTNGFSGSDLREMCRNASVYRMRQLITS-----RDPSATALDRNNVR 337 Query: 330 LTLDDFKYAMARIK 343 +T+DD + +IK Sbjct: 338 ITMDDLLGSHLKIK 351 >gi|11428694 fidgetin; hypothetical protein FLJ10405 [Homo sapiens] Length = 693 Score = 132 bits (330), Expect = 4e-30 Identities = 89/281 (31%), Positives = 148/281 (51%), Gaps = 17/281 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSPIEP-----PQGILLFGPPGTGKSLLASAVANS 144 + WNDI GL K +I + + + +S P+ ILLFGP GTGK+LL +A+ Sbjct: 417 VDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQ 476 Query: 145 LNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDA-A 203 L ATFF + S L++K+ GE+ K+I A F +AR PSVIF+ ++D L +V+ + + Sbjct: 477 LGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHSPV 536 Query: 204 RRMIGTLLAEMDG-FKERKDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIF 262 RM L ++D +D+++V+ AT+ P ++DE++ R+ +PLPD + +I Sbjct: 537 SRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQII 596 Query: 263 KIHLRGIHYDVPLSRLAKEAVKRL--YSGREIANVVKLATMKMLEEMNPELSDPLRVSTL 320 L +Y + A V+R +SG ++A++ + A + L M + S L Sbjct: 597 VQLLSQHNYCLNDKEFAL-LVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQL 655 Query: 321 KGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 RP+T DF+ A +I+ I++ ++ Y W K F Sbjct: 656 -------RPVTYQDFENAFCKIQPSISQKELDMYVEWNKMF 689 >sp|O14126|PRSA_SCHPO 26S PROTEASE REGULATORY SUBUNIT 6A >gi|7435746|pir||T11634 26S proteasome regulatory particle chain RPT5 - fission yeast (Schizosaccharomyces pombe) >gi|2414640|emb|CAB16387.1| (Z99260) probable 26s protease regulatory subunit 6a. [Schizosaccharomyces pombe] >gi|6681372|dbj|BAA88693.1| (AB012136) regulatory subunit of 26S proteasome [Schizosaccharomyces pombe] Length = 438 Score = 132 bits (328), Expect = 8e-30 Identities = 89/254 (35%), Positives = 147/254 (57%), Gaps = 19/254 (7%) Query: 75 NEYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILL 126 +EY ++KA+ ++ T ++DIGGL + + + +AI L + ++ ++PP+G L+ Sbjct: 165 SEYDSRVKAMEVDEKPTERYSDIGGLSKQIEELFEAIVLPMQQADKFRKLGVKPPKGCLM 224 Query: 127 FGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFI 186 FGPPGTGK+LLA A A NATF + A L+ + G+ +KL+ F+LA++ SP++IFI Sbjct: 225 FGPPGTGKTLLARACAAQSNATFLKLAAPQLVQMFIGDGAKLVRDAFALAKEKSPAIIFI 284 Query: 187 DEVDSLTMKRVSLDDA----ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML- 241 DE+D++ KR + A +R + LL ++DGF D+V V+ ATN LD A+L Sbjct: 285 DELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFSS-DDRVKVIAATNRVDTLDPALLR 343 Query: 242 -SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANVVKL 298 RL ++ PLP+ + V I +IH R I D+ LA+ + Y+G + +V Sbjct: 344 SGRLDRKLEFPLPNEEARVGILRIHSRKMAIDDDINWEELARSTDE--YNGAMLKSVCVE 401 Query: 299 ATMKMLEEMNPELS 312 A M L + + +++ Sbjct: 402 AGMIALRQGDTKIN 415 >gi|11181772 fidgetin; fidget [Mus musculus] >gi|10442027|gb|AAG17289.1|AF263913_1 (AF263913) fidgetin [Mus musculus] Length = 759 Score = 132 bits (328), Expect = 8e-30 Identities = 89/281 (31%), Positives = 148/281 (51%), Gaps = 17/281 (6%) Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSPIEP-----PQGILLFGPPGTGKSLLASAVANS 144 + W+DI GL K +I + + + +S P+ ILLFGP GTGK+LL +A+ Sbjct: 483 VDWSDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQ 542 Query: 145 LNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDA-A 203 L ATFF + S L++K+ GE+ K+I A F +AR PSVIF+ ++D L +VS + + Sbjct: 543 LGATFFKIAGSGLVAKWIGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVSEEHSPV 602 Query: 204 RRMIGTLLAEMDG-FKERKDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIF 262 RM L ++D +D+++V+ AT+ P ++DE++ R+ +PLPD + +I Sbjct: 603 SRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQII 662 Query: 263 KIHLRGIHYDVPLSRLAKEAVKRL--YSGREIANVVKLATMKMLEEMNPELSDPLRVSTL 320 L +Y + A V+R +SG ++A++ + A + L M + S L Sbjct: 663 VQLLTQHNYCLNDKEFAL-LVQRTEGFSGLDVAHLCQEAAVGPLHAMPATDLSAIMPSQL 721 Query: 321 KGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 RP+T DF+ A +I+ I++ ++ Y W K F Sbjct: 722 -------RPVTYQDFENAFCKIQPSISQKELDMYVEWNKMF 755 >emb|CAB62856.1| (AL035475) hypothetical protein MAL4P2.15 [Plasmodium falciparum] Length = 667 Score = 131 bits (326), Expect = 1e-29 Identities = 90/278 (32%), Positives = 147/278 (52%), Gaps = 17/278 (6%) Query: 93 NDIGGLREAKKLIAQAIGLSIAKSPI-----EPPQGILLFGPPGTGKSLLASAVANSLNA 147 +DI GL + KK+I I I + + +GILLFGPPGTGK+++A VA+S Sbjct: 391 SDIIGLYDIKKIIKDKIVNVILRPDLFTGLNRAAKGILLFGPPGTGKTMVAKWVASSCKC 450 Query: 148 TFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLT-MKRVSLDDAARRM 206 +F++V S L SKY GE+ K+++ALF A +PS++F DE+DSL ++ DD R+ Sbjct: 451 SFYNVNTSSLFSKYIGETEKIVTALFKCAEVDNPSILFFDEIDSLLGTRKKDEDDTTIRI 510 Query: 207 IGTLLAEMDGFKERKDKVIVLT-ATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVE-IFKI 264 LL +DG +KD +IV+ ATN P +D+A L R R+Y+PLPD N+ E I I Sbjct: 511 KNQLLQMIDGINTKKDIIIVIIGATNRPDMIDDAALRRFNKRVYIPLPDFNARKEQIRYI 570 Query: 265 HLRGIHYDVPLSRLAKEAVK---RLYSGREIANVVKLATMKMLEEMNPELSDPLRVSTLK 321 + H L+ +A+ ++G +I ++ + ++ + + + Sbjct: 571 ISKHTHSGFQLTEEELDAISVKLENWNGSDIYHLCSKCYEYVYDDAVEQYNGIQNIPNAS 630 Query: 322 GRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAK 359 R + +DF AM ++ + + +V Y+ W+K Sbjct: 631 ----IFRAIQFNDFIKAMTQVNT--SYKNVFDYDEWSK 662 >gb|AAF01545.1|AC009325_15 (AC009325) putative cell division control protein [Arabidopsis thaliana] Length = 703 Score = 130 bits (324), Expect = 2e-29 Identities = 103/326 (31%), Positives = 157/326 (47%), Gaps = 34/326 (10%) Query: 55 EEAKKW------EEKAKNVRKRREGKNEYFDKLKALIKRS------TITWNDIGGLREAK 102 E+ K W EE+ + + + E + ++A + R + W+D+GGL + Sbjct: 361 EDDKSWLRMPWPEEELEKLFVKMSDFEEAVNLVQASLTREGFSIVPDVKWDDVGGLDHLR 420 Query: 103 KLIAQAIGLSIAKSPI------EPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASD 156 + I I K I + G LL+GPPG GK+L+A A AN A F +K ++ Sbjct: 421 LQFNRYIVRPIKKPDIYKAFGVDLETGFLLYGPPGCGKTLIAKAAANEAGANFMHIKGAE 480 Query: 157 LLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDD-AARRMIGTLLAEMD 215 LL+KY GES I LF AR +P VIF DEVD+LT R R++ L E+D Sbjct: 481 LLNKYVGESELAIRTLFQRARTCAPCVIFFDEVDALTTSRGKEGAWVVERLLNQFLVELD 540 Query: 216 GFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHY 271 G + R V V+ ATN P +D A L R +YVPLP+ + I K R I Sbjct: 541 GGERR--NVYVIGATNRPDVVDPAFLRPGRFGNLLYVPLPNADERASILKAIARKKPIDP 598 Query: 272 DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEM--NPELSDPLRVSTLKGRDLTTRP 329 V L +AK + +SG ++A++V+ AT + +EEM + E S+ D+T Sbjct: 599 SVDLDGIAKNNCEG-FSGADLAHLVQKATFQAVEEMIGSSESSED------DVTDITQCT 651 Query: 330 LTLDDFKYAMARIKSPITKSDVKKYE 355 + F+ A++ + + K + Y+ Sbjct: 652 IKTRHFEQALSLVSPSVNKQQRRHYD 677 Score = 107 bits (265), Expect = 2e-22 Identities = 70/235 (29%), Positives = 120/235 (50%), Gaps = 18/235 (7%) Query: 91 TWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKSLLASAVANS 144 T+ D GG+++ + + I K ++PP GIL GPPG GK+ LA+A+AN Sbjct: 114 TFKDFGGIKKILDELEMNVLFPILNPEPFKKIGVKPPSGILFHGPPGCGKTKLANAIANE 173 Query: 145 LNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD-DAA 203 F+ + A++++S G S + I LFS A + +PS++FIDE+D++ KR + + Sbjct: 174 AGVPFYKISATEVISGVSGASEENIRELFSKAYRTAPSIVFIDEIDAIGSKRENQQREME 233 Query: 204 RRMIGTLLAEMDGFKERKDK---------VIVLTATNAPWDLDEAM--LSRLPIRIYVPL 252 +R++ LL MDG + DK V+V+ ATN P LD A+ R I + Sbjct: 234 KRIVTQLLTCMDGPGNKGDKNAPDSSAGFVLVIGATNRPDALDPALRRSGRFETEIALTA 293 Query: 253 PDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEM 307 PD ++ EI + + + + P + + + G ++ +V LA K ++ + Sbjct: 294 PDEDARAEILSVVAQKLRLEGPFDKKRIARLTPGFVGADLESVAYLAGRKAIKRI 348 >sp|P54777|PEX6_RAT PEROXISOME ASSEMBLY FACTOR-2 (PAF-2) (PEROXISOMAL-TYPE ATPASE 1) (PEROXIN-6) >gi|1127034|dbj|BAA09824.1| (D63673) peroxisome assembly factor-2 [Rattus norvegicus] >gi|1586820|prf||2204387A peroxisome assembly factor 2 [Rattus norvegicus] Length = 978 Score = 130 bits (323), Expect = 3e-29 Identities = 92/293 (31%), Positives = 154/293 (52%), Gaps = 28/293 (9%) Query: 86 KRSTITWNDIGGLREAKKLIAQAIGLSIAKSPIEPPQ---------GILLFGPPGTGKSL 136 K +++W+D+GGL++ KK I + I L P+E P+ G+LL GPPGTGK+L Sbjct: 696 KIPSVSWHDVGGLQDVKKEILETIQL-----PLEHPELLSLGLRRSGLLLHGPPGTGKTL 750 Query: 137 LASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR 196 LA AVA + TF SVK +L++ Y G+S + + +F+ AR +P +IF DE+DSL R Sbjct: 751 LAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSR 810 Query: 197 VSLDDAA---RRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYV- 250 D+ R++ LLAE+DG +D V V+ ATN P LD A+L R ++V Sbjct: 811 GRSGDSGGVMDRVVSQLLAELDGLHSTQD-VFVIGATNRPDLLDPALLRPGRFDKLVFVG 869 Query: 251 PLPDVNSAVEIFKIHLRGIHYDVPLSRL-AKEAVKRLYSGREIANVVKLATMKMLEEMNP 309 D S + + R + +S + + +G ++ ++ A M L+ Sbjct: 870 ASEDRASQLRVLSAITRKFKLEASVSLMNVLDCCPPQLTGADLYSLCSDAMMTALKRRVR 929 Query: 310 ELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEFA 362 +L + L + + LT++D A AR++ +++ ++ +Y+R ++FA Sbjct: 930 DLEEGLEPRS------SALLLTMEDLLQAAARLQPSVSEQELLRYKRIQRKFA 976 >dbj|BAA24931.1| (D89660) peroxisome assembly factor-2 [Rattus norvegicus] Length = 978 Score = 130 bits (323), Expect = 3e-29 Identities = 92/293 (31%), Positives = 154/293 (52%), Gaps = 28/293 (9%) Query: 86 KRSTITWNDIGGLREAKKLIAQAIGLSIAKSPIEPPQ---------GILLFGPPGTGKSL 136 K +++W+D+GGL++ KK I + I L P+E P+ G+LL GPPGTGK+L Sbjct: 696 KIPSVSWHDVGGLQDVKKEILETIQL-----PLEHPELLSLGLRRSGLLLHGPPGTGKTL 750 Query: 137 LASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKR 196 LA AVA + TF SVK +L++ Y G+S + + +F+ AR +P +IF DE+DSL R Sbjct: 751 LAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSR 810 Query: 197 VSLDDAA---RRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYV- 250 D+ R++ LLAE+DG +D V V+ ATN P LD A+L R ++V Sbjct: 811 GRSGDSGGVMDRVVSQLLAELDGLHSTQD-VFVIGATNRPDLLDPALLRPGRFDKLVFVG 869 Query: 251 PLPDVNSAVEIFKIHLRGIHYDVPLSRL-AKEAVKRLYSGREIANVVKLATMKMLEEMNP 309 D S + + R + +S + + +G ++ ++ A M L+ Sbjct: 870 ASEDRASQLRVLSAITRKFKLEASVSLMNVLDCCPPQLTGADLYSLCSDAMMTALKRRVR 929 Query: 310 ELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEFA 362 +L + L + + LT++D A AR++ +++ ++ +Y+R ++FA Sbjct: 930 DLEEGLEPRS------SALLLTMEDLLQAAARLQPSVSEQELLRYKRIQRKFA 976 >gb|AAG09749.1|AF233277_1 (AF233277) peroxin-6 [Penicillium chrysogenum] Length = 1459 Score = 130 bits (323), Expect = 3e-29 Identities = 107/364 (29%), Positives = 177/364 (48%), Gaps = 34/364 (9%) Query: 28 ARLIALRCAELLRKIASENLSLSHILLE--EAKKWEEKAKNVRKRREGKNEYFDKLKALI 85 ARL +L AE +KI+ + + +LL + + KA + + D + A Sbjct: 966 ARLESL--AEASKKISGSEVFVRDVLLAGGDGARGVTKADFDAAVEAARKNFADSIGAP- 1022 Query: 86 KRSTITWNDIGGLREAKKLIAQAIGLSIAKSPI-----EPPQGILLFGPPGTGKSLLASA 140 K + W+D+GGL K + + I L + + + + GIL +GPPGTGK+LLA A Sbjct: 1023 KIPNVGWDDVGGLTNVKDALVETIQLPLERPELFAKGMKKRSGILFYGPPGTGKTLLAKA 1082 Query: 141 VANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD 200 +A + FFSVK +LL+ Y GES + +F AR P V+F DE+DS+ KR + Sbjct: 1083 IATEFSLNFFSVKGPELLNMYIGESEANVRRVFQRARDARPCVVFFDELDSVAPKRGNQG 1142 Query: 201 DAA---RRMIGTLLAEMDGF---KERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPL 252 D+ R++ LLAE+DG +E V V+ ATN P LD A+L R +Y+ + Sbjct: 1143 DSGGVMDRIVSQLLAELDGMNGGEENSGGVFVIGATNRPDLLDTALLRPGRFDKMLYLGV 1202 Query: 253 PDVN-SAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKML----- 304 D + I + R +H DV L R+A E + Y+G ++ + A +K + Sbjct: 1203 SDTHRKQATILEALTRKFALHPDVSLDRVA-EQLPLTYTGADLYALCSDAMLKAITRKAT 1261 Query: 305 ---EEMNPELSDPLRVS----TLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERW 357 E++N + P+ + L ++ +T +DF A + ++ +++ +ER Sbjct: 1262 AVDEKINALPNGPVSTAWFFDHLATKEDVNVMVTEEDFLSAQGELVPSVSAKELEHFERI 1321 Query: 358 AKEF 361 + F Sbjct: 1322 RQTF 1325 >gi|6324691 26S protease regulatory subunit; Rpt5p [Saccharomyces cerevisiae] >gi|464859|sp|P33297|PRSA_YEAST 26S PROTEASE REGULATORY SUBUNIT 6A (TAT-BINDING PROTEIN HOMOLOG 1) (TBP-1) >gi|626983|pir||S46605 26S proteasome regulatory particle chain RPT5 - yeast (Saccharomyces cerevisiae) >gi|313878|emb|CAA51971.1| (X73569) yeast tat-binding analog [Saccharomyces cerevisiae] >gi|1050819|emb|CAA62114.1| (X90518) ORF O3258 [Saccharomyces cerevisiae] >gi|1164962|emb|CAA64037.1| (X94335) YOR3258w [Saccharomyces cerevisiae] >gi|1420311|emb|CAA99315.1| (Z75025) ORF YOR117w [Saccharomyces cerevisiae] Length = 434 Score = 129 bits (322), Expect = 4e-29 Identities = 82/212 (38%), Positives = 127/212 (59%), Gaps = 15/212 (7%) Query: 75 NEYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILL 126 +E+ ++KA+ ++ T T++D+GGL + + + +AI L + ++ I P+G L+ Sbjct: 161 SEFDSRVKAMEVDEKPTETYSDVGGLDKQIEELVEAIVLPMKRADKFKDMGIRAPKGALM 220 Query: 127 FGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFI 186 +GPPGTGK+LLA A A NATF + A L+ Y GE +KL+ F+LA++ +P++IFI Sbjct: 221 YGPPGTGKTLLARACAAQTNATFLKLAAPQLVQMYIGEGAKLVRDAFALAKEKAPTIIFI 280 Query: 187 DEVDSLTMKRV----SLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML- 241 DE+D++ KR S D +R + LL ++DGF D+V VL ATN LD A+L Sbjct: 281 DELDAIGTKRFDSEKSGDREVQRTMLELLNQLDGFSS-DDRVKVLAATNRVDVLDPALLR 339 Query: 242 -SRLPIRIYVPLPDVNSAVEIFKIHLRGIHYD 272 RL +I PLP +S +I +IH R + D Sbjct: 340 SGRLDRKIEFPLPSEDSRAQILQIHSRKMTTD 371 >sp|O23894|PRSA_BRACM 26S PROTEASE REGULATORY SUBUNIT 6A HOMOLOG (TAT-BINDING PROTEIN HOMOLOG 1) (TBP-1) >gi|2564337|dbj|BAA22951.1| (D88663) Tat binding protein 1 [Brassica rapa] Length = 424 Score = 129 bits (322), Expect = 4e-29 Identities = 81/222 (36%), Positives = 127/222 (56%), Gaps = 17/222 (7%) Query: 75 NEYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILL 126 +EY ++KA+ ++ T +NDIGGL + + + +AI L + K + PP+G+LL Sbjct: 151 SEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMTHKERFEKLGVRPPKGVLL 210 Query: 127 FGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFI 186 +GPPGTGK+L+A A A NATF + L+ + G+ +KL+ F LA++ +P +IFI Sbjct: 211 YGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKLVRDAFQLAKEKAPCIIFI 270 Query: 187 DEVDSLTMKR----VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML- 241 DE+D++ KR VS D +R + LL ++DGF +++ V+ ATN LD A++ Sbjct: 271 DEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSS-DERIKVIAATNRADILDPALMR 329 Query: 242 -SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAK 280 RL +I P P + I +IH R +H DV LA+ Sbjct: 330 SGRLDRKIEFPHPTEEARARILQIHSRKMNVHPDVNFEELAR 371 >sp|O67077|FTSH_AQUAE CELL DIVISION PROTEIN FTSH HOMOLOG >gi|7446574|pir||B70381 cell division protein FtsH - Aquifex aeolicus >gi|2983448|gb|AAC07029.1| (AE000714) cell division protein FtsH [Aquifex aeolicus] Length = 634 Score = 129 bits (322), Expect = 4e-29 Identities = 85/256 (33%), Positives = 137/256 (53%), Gaps = 28/256 (10%) Query: 78 FDKLKALI---KRSTITWNDIGGLREAKKLIAQAIGLSIAKSPIE-------PPQGILLF 127 F K +A + ++ +T+ D+ G+ E K+ + + I K P++ PP+G+LL+ Sbjct: 137 FGKSRAKVYIEEKPKVTFKDVAGIEEVKEEVKEII--EYLKDPVKFQKLGGRPPKGVLLY 194 Query: 128 GPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFID 187 G PG GK+LLA A+A + F SV SD + + G + + LF A++ +P +IFID Sbjct: 195 GEPGVGKTLLAKAIAGEAHVPFISVSGSDFVEMFVGVGAARVRDLFETAKKHAPCIIFID 254 Query: 188 EVDSLTMKRVSL-----DDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML- 241 E+D++ R ++ D + + LL EMDGF + D +IV+ ATN P LD A+L Sbjct: 255 EIDAVGRARGAIPVGGGHDEREQTLNQLLVEMDGF-DTSDGIIVIAATNRPDILDPALLR 313 Query: 242 -SRLPIRIYVPLPDVNSAVEIFKIHLRG--IHYDVPLSRLAKEAVKRLYSGREIANVVK- 297 R +I++P PDV EI K+H R + DV L +A+ ++G ++ N++ Sbjct: 314 PGRFDRQIFIPKPDVRGRYEILKVHARNKKLAKDVDLEFVARATPG--FTGADLENLLNE 371 Query: 298 ---LATMKMLEEMNPE 310 LA K EE+ E Sbjct: 372 AALLAARKGKEEITME 387 >gb|AAD46145.1| (AF081573) 19S proteasome regulatory complex subunit S6A [Arabidopsis thaliana] Length = 424 Score = 129 bits (322), Expect = 4e-29 Identities = 81/222 (36%), Positives = 127/222 (56%), Gaps = 17/222 (7%) Query: 75 NEYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILL 126 +EY ++KA+ ++ T +NDIGGL + + + +AI L + K + PP+G+LL Sbjct: 151 SEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMTHKERFEKLGVRPPKGVLL 210 Query: 127 FGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFI 186 +GPPGTGK+L+A A A NATF + L+ + G+ +KL+ F LA++ +P +IFI Sbjct: 211 YGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKLVRDAFQLAKEKAPCIIFI 270 Query: 187 DEVDSLTMKR----VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML- 241 DE+D++ KR VS D +R + LL ++DGF +++ V+ ATN LD A++ Sbjct: 271 DEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSS-DERIKVIAATNRADILDPALMR 329 Query: 242 -SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAK 280 RL +I P P + I +IH R +H DV LA+ Sbjct: 330 SGRLDRKIEFPHPTEEARARILQIHSRKMNVHPDVHFEELAR 371 >gb|AAF22525.1|AF123394_1 (AF123394) 26S proteasome AAA-ATPase subunit RPT5a [Arabidopsis thaliana] >gi|7596759|gb|AAF64530.1| (AC009606) 26S proteasome AAA-ATPase subunit RPT5a [Arabidopsis thaliana] Length = 424 Score = 129 bits (322), Expect = 4e-29 Identities = 81/222 (36%), Positives = 127/222 (56%), Gaps = 17/222 (7%) Query: 75 NEYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILL 126 +EY ++KA+ ++ T +NDIGGL + + + +AI L + K + PP+G+LL Sbjct: 151 SEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMTHKERFEKLGVRPPKGVLL 210 Query: 127 FGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFI 186 +GPPGTGK+L+A A A NATF + L+ + G+ +KL+ F LA++ +P +IFI Sbjct: 211 YGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKLVRDAFQLAKEKAPCIIFI 270 Query: 187 DEVDSLTMKR----VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML- 241 DE+D++ KR VS D +R + LL ++DGF +++ V+ ATN LD A++ Sbjct: 271 DEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSS-DERIKVIAATNRADILDPALMR 329 Query: 242 -SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAK 280 RL +I P P + I +IH R +H DV LA+ Sbjct: 330 SGRLDRKIEFPHPTEEARARILQIHSRKMNVHPDVNFEELAR 371 >sp|P46465|PRSA_ORYSA 26S PROTEASE REGULATORY SUBUNIT 6A HOMOLOG (TAT-BINDING PROTEIN HOMOLOG 1) (TBP-1) >gi|556560|dbj|BAA04614.1| (D17788) rice homologue of Tat binding protein [Oryza sativa] Length = 429 Score = 129 bits (320), Expect = 7e-29 Identities = 82/222 (36%), Positives = 127/222 (56%), Gaps = 17/222 (7%) Query: 75 NEYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILL 126 +EY ++KA+ ++ T +NDIGGL + + + +AI L + K I PP+G+LL Sbjct: 156 SEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMTHKDRFQKLGIRPPKGVLL 215 Query: 127 FGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFI 186 +GPPGTGK+L+A A A NATF + L+ + G+ +KL+ F LA++ SP +IFI Sbjct: 216 YGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKLVRDAFQLAKEKSPCIIFI 275 Query: 187 DEVDSLTMKR----VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML- 241 DE+D++ KR VS D +R + LL ++DGF +++ V+ ATN LD A++ Sbjct: 276 DEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSS-DERIKVIAATNRADILDPALMR 334 Query: 242 -SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAK 280 RL +I P P + I +IH R ++ DV LA+ Sbjct: 335 SGRLDRKIEFPHPSEEARARILQIHSRKMNVNPDVNFEELAR 376 >sp|O13764|PEX6_SCHPO PROBABLE PEROXIN-6 >gi|7492793|pir||T37816 probable peroxin-6, AAA family atpase - fission yeast (Schizosaccharomyces pombe) >gi|2370473|emb|CAB11501.1| (Z98849) putative peroxin-6, AAA family atpase [Schizosaccharomyces pombe] Length = 948 Score = 129 bits (320), Expect = 7e-29 Identities = 97/326 (29%), Positives = 161/326 (48%), Gaps = 45/326 (13%) Query: 68 RKRREGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIA-----KSPIEPPQ 122 R R+E N F K + W+DIGGL EAK ++ + L + ++P Sbjct: 637 RIRKEKSNTIFTVPK-------VNWDDIGGLEEAKTVLRDTLQLPLQFPELFSQGLKPRS 689 Query: 123 GILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPS 182 G+LL+GPPGTGK+LLA AVA L+ F S+K +LL+ Y GES + +F AR SP Sbjct: 690 GVLLYGPPGTGKTLLAKAVATELSLEFVSIKGPELLNMYVGESEANVRNVFEKARNSSPC 749 Query: 183 VIFIDEVDSLTMKRVSLDDAAR---RMIGTLLAEMDGFKERKDK-VIVLTATNAPWDLDE 238 VIF DE+DS+ R + D+ R++ LLAE+D + +K V V+ ATN P LD Sbjct: 750 VIFFDELDSIAPHRGNSSDSGNVMDRVVSQLLAELDSISKDNNKYVFVIGATNRPDLLDP 809 Query: 239 AML--SRLPIRIYVPLPDVNSAVEIFKIHLRG------IHYDVPLSRLAKEAVKRLYSGR 290 ++L R +Y+ +N + E LR + + L+ +AK ++G Sbjct: 810 SLLRPGRFDKLVYL---GINKSEESKASMLRALTKTFKLDETIDLNEIAKNCHPN-FTGA 865 Query: 291 EIANVVKLATMKMLEEMNPELSDPLRVSTLKGRDLTTRP--------------LTLDDFK 336 ++ + A + ++ E+ ++ S G DL+T +T +DF Sbjct: 866 DMYALCSDAVLSAIKRKTNEIDLLIQAS---GTDLSTEEFFKRNENQDSLELRITKEDFL 922 Query: 337 YAMARIKSPITKSDVKKYERWAKEFA 362 ++ +++ I++ ++ +YE +F+ Sbjct: 923 TSLKKLRPSISEQELHRYEMVRHQFS 948 >sp|O04019|PRSA_ARATH 26S PROTEASE REGULATORY SUBUNIT 6A HOMOLOG (TAT-BINDING PROTEIN HOMOLOG 1) (TBP-1) >gi|2342675|gb|AAB70397.1| (AC000106) Similar to probable Mg-dependent ATPase (pir|S56671). ESTs gb|T46782,gb|AA04798 come from this gene. [Arabidopsis thaliana] Length = 419 Score = 128 bits (319), Expect = 9e-29 Identities = 83/222 (37%), Positives = 127/222 (56%), Gaps = 17/222 (7%) Query: 75 NEYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILL 126 +EY ++KA+ ++ T +NDIGGL + + + +AI L + K I PP+G+LL Sbjct: 146 SEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMTHKEQFEKLGIRPPKGVLL 205 Query: 127 FGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFI 186 +GPPGTGK+L+A A A NATF + L+ + G+ +KL+ F LA++ SP +IFI Sbjct: 206 YGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKLVRDAFLLAKEKSPCIIFI 265 Query: 187 DEVDSLTMKR----VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML- 241 DE+D++ KR VS D +R + LL ++DGF D++ V+ ATN LD A++ Sbjct: 266 DEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSS-DDRIKVIAATNRADILDPALMR 324 Query: 242 -SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAK 280 RL +I P P + I +IH R ++ DV LA+ Sbjct: 325 SGRLDRKIEFPHPTEEARGRILQIHSRKMNVNADVNFEELAR 366 >gi|6321465 40 kDa putative membrane-spanning ATPase; Msp1p [Saccharomyces cerevisiae] >gi|462627|sp|P28737|MSP1_YEAST MSP1 PROTEIN (TAT-BINDING HOMOLOG 4) >gi|1362427|pir||A49506 MSP1 protein - yeast (Saccharomyces cerevisiae) >gi|404217|emb|CAA48191.1| (X68055) MSP1 protein [Saccharomyces cerevisiae] >gi|531756|emb|CAA56956.1| (X81069) probable regulatory subunit of 26S protease [Saccharomyces cerevisiae] >gi|1323004|emb|CAA97015.1| (Z72813) ORF YGR028w [Saccharomyces cerevisiae] Length = 362 Score = 128 bits (318), Expect = 1e-28 Identities = 92/302 (30%), Positives = 154/302 (50%), Gaps = 27/302 (8%) Query: 55 EEAKKWEEKAKNVRKRREGKNEYFDK--LKALIKRS--TITWNDIGGLREAKKLIAQAIG 110 +++ +WE+ K E + +++ L +++ IT+ DIGGL + +++ Sbjct: 49 KQSLQWEKLVKRSPALAEVTLDAYERTILSSIVTPDEINITFQDIGGLDPLISDLHESVI 108 Query: 111 LSI------AKSPI-EPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFG 163 + + SP+ + P G+LL+GPPG GK++LA A+A A F S++ S ++ K++G Sbjct: 109 YPLMMPEVYSNSPLLQAPSGVLLYGPPGCGKTMLAKALAKESGANFISIRMSSIMDKWYG 168 Query: 164 ESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDAARRMIGTLLAEM----DGFKE 219 ES+K++ A+FSLA +L P +IFIDE+DS +R S D + TL AE DG Sbjct: 169 ESNKIVDAMFSLANKLQPCIIFIDEIDSFLRERSSTD---HEVTATLKAEFMTLWDGLL- 224 Query: 220 RKDKVIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYD---VPLS 276 +V+++ ATN D+D+A L RLP R V LP + +I + L+ D L Sbjct: 225 NNGRVMIIGATNRINDIDDAFLRRLPKRFLVSLPGSDQRYKILSVLLKDTKLDEDEFDLQ 284 Query: 277 RLAKEAVKRLYSGREIANVVKLATMKMLEE---MNPELSDPLRVSTLKGRDLTTRPLTLD 333 +A + +SG ++ + + A + +E +L D + L RPL Sbjct: 285 LIADNT--KGFSGSDLKELCREAALDAAKEYIKQKRQLIDSGTIDVNDTSSLKIRPLKTK 342 Query: 334 DF 335 DF Sbjct: 343 DF 344 >sp|P54776|PRSA_LYCES 26S PROTEASE REGULATORY SUBUNIT 6A HOMOLOG (TAT-BINDING PROTEIN HOMOLOG 1) (TBP-1) (MG(2+)-DEPENDENT ATPASE 1) (LEMA-1) >gi|1362099|pir||S56672 probable 26S proteinase chain MA-1 - tomato >gi|732815|emb|CAA52445.1| (X74426) Mg-dependent ATPase 1 [Lycopersicon esculentum] Length = 423 Score = 127 bits (317), Expect = 1e-28 Identities = 81/222 (36%), Positives = 127/222 (56%), Gaps = 17/222 (7%) Query: 75 NEYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILL 126 +EY ++KA+ ++ T ++DIGGL + + + +AI L + K + PP+G+LL Sbjct: 150 SEYDSRVKAMEVDEKPTEDYHDIGGLEKQIQELVEAIVLPMTHQERFQKLGVRPPKGVLL 209 Query: 127 FGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFI 186 +GPPGTGK+L+A A A NATF + L+ + G+ +KL+ F LA++ SP +IFI Sbjct: 210 YGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKLVRDAFQLAKEKSPCIIFI 269 Query: 187 DEVDSLTMKR----VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML- 241 DE+D++ KR VS D +R + LL ++DGF D++ V+ ATN LD A++ Sbjct: 270 DEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSS-DDRIKVIAATNRADILDPALMR 328 Query: 242 -SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAK 280 RL +I P P + I +IH R ++ DV LA+ Sbjct: 329 SGRLDRKIEFPHPTEEARARILQIHSRKMNVNPDVNFEELAR 370 >dbj|BAA88165.1| (AB024399) FtsH (FtsHcp) [Cyanidioschyzon merolae] Length = 603 Score = 127 bits (316), Expect = 2e-28 Identities = 82/242 (33%), Positives = 137/242 (55%), Gaps = 23/242 (9%) Query: 78 FDKLKA---LIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPIE-------PPQGILLF 127 F K KA ++ ++ I ++D+ G+ EAK+ +A+ + + K+P + P+G+LL Sbjct: 136 FGKSKARFQMVAKTGIMFDDVAGIEEAKEELAEVV--AFLKNPSKFLAVGASIPKGVLLV 193 Query: 128 GPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFID 187 GPPGTGK+LLA A+A + FFS+ S+ + + G + + LF A+Q +P ++FID Sbjct: 194 GPPGTGKTLLAKAIAGEASVPFFSISGSEFVEMFVGVGASRVRDLFKKAKQNAPCLVFID 253 Query: 188 EVDSLTMKRVS----LDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML-- 241 E+D++ +R + +D + + LL EMDGF E VIV+ ATN LD A+L Sbjct: 254 EIDAVGRQRGAGIGGGNDEREQTLNQLLTEMDGF-EGNTGVIVIAATNRVDVLDAALLRP 312 Query: 242 SRLPIRIYVPLPDVNSAVEIFKIHL--RGIHYDVPLSRLAKEAVKRLYSGREIANVVKLA 299 R +I V +PDV S + I K+H + +H V L +A+ ++G ++AN++ A Sbjct: 313 GRFDRQIMVSMPDVKSRIAILKVHANQKKLHPQVSLEAVARRTAG--FAGADLANLLNEA 370 Query: 300 TM 301 + Sbjct: 371 AI 372 >sp|P46468|CDAT_PLAFA PUTATIVE CELL DIVISION CYCLE ATPASE >gi|552189|gb|AAA29520.1| (M96757) cell division cycle ATPase [Plasmodium falciparum] Length = 709 Score = 127 bits (315), Expect = 3e-28 Identities = 71/159 (44%), Positives = 98/159 (60%), Gaps = 9/159 (5%) Query: 89 TITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKSLLASAVA 142 T+TWNDIGG+ E K+ + + I + K +GILL+GPPG GK+LLA A+A Sbjct: 552 TVTWNDIGGMNEVKEQLKETILYPLEYKHLYNKFNSNYNKGILLYGPPGCGKTLLAKAIA 611 Query: 143 NSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVS--LD 200 N A F SVK +LL+ +FGES + LF AR SP +IF DE+DSL +R S + Sbjct: 612 NECKANFISVKGPELLTMWFGESEANVRDLFDKARAASPCIIFFDEIDSLAKERNSNTNN 671 Query: 201 DAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEA 239 DA+ R+I +L E+DG E+K + ++ ATN P LD+A Sbjct: 672 DASDRVINQILTEIDGINEKK-TIFIIAATNRPDILDKA 709 Score = 123 bits (306), Expect = 3e-27 Identities = 85/267 (31%), Positives = 139/267 (51%), Gaps = 16/267 (5%) Query: 52 ILLEEAKKWEEKAKNVRKRREGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGL 111 I+ EE++ E + EY + IT+ D+GG+++ I + I L Sbjct: 108 IISEESENEEFGCIGEHSQLTLAEEYLKREDYEENNDDITYEDLGGMKKQLNKIRELIEL 167 Query: 112 SIAKSP-------IEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGE 164 + K P I P+G+L+ G PGTGK+ +A A+AN NA + + +++SK+ GE Sbjct: 168 PL-KYPEIFMSIGISAPKGVLMHGIPGTGKTSIAKAIANESNAYCYIINGPEIMSKHIGE 226 Query: 165 SSKLISALFSLARQLSPSVIFIDEVDSLTMKR-VSLDDAARRMIGTLLAEMDGFKERKDK 223 S + + +F A + +P +IFIDE+DS+ KR S ++ +R++ LL MDG K + + Sbjct: 227 SEQKLRKIFKKASEKTPCIIFIDEIDSIANKRSKSNNELEKRVVSQLLTLMDGLK-KNNN 285 Query: 224 VIVLTATNAPWDLDEAM--LSRLPIRIYVPLPDVNSAVEIF--KIHLRGIHYDVPLSRLA 279 V+VL ATN P +D A+ R I +P+PD EI K + DV L ++A Sbjct: 286 VLVLAATNRPNSIDPALRRFGRFDREIEIPVPDEQGRYEILLTKTKKMKLDPDVNLRKIA 345 Query: 280 KEAVKRLYSGREIANVVKLATMKMLEE 306 KE Y G ++A + A ++ ++E Sbjct: 346 KEC--HGYVGADLAQLCFEAAIQCIKE 370 >gb|AAF91248.1|AF227504_1 (AF227504) proteasome regulatory ATPase subunit 6 [Trypanosoma brucei] Length = 408 Score = 127 bits (315), Expect = 3e-28 Identities = 84/207 (40%), Positives = 121/207 (57%), Gaps = 20/207 (9%) Query: 79 DKLKALIK----RSTITWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLF 127 D L +L+K S T+++IGGL K I + I LS+ K P I P+G+LL+ Sbjct: 132 DPLVSLMKVENAGSESTYDEIGGLSRQVKEIKEVIELSV-KHPELFEALGIAQPKGVLLY 190 Query: 128 GPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFID 187 GPPGTGK+LLA AVA+ + TF V ++L+ KY GE ++L+ LF +AR+ SPS+IF+D Sbjct: 191 GPPGTGKTLLARAVAHHTDCTFIRVSGAELVQKYIGEGARLVRELFVMAREHSPSIIFMD 250 Query: 188 EVDSLTMKRVSL-----DDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML- 241 E+DS+ R+ D +R + LL ++DGF E + V+ ATN LDEA+L Sbjct: 251 EIDSIGSTRLENTGRGGDSEVQRTMLELLNQLDGF-ESTQSIKVIMATNRVDILDEALLR 309 Query: 242 -SRLPIRIYVPLPDVNSAVEIFKIHLR 267 R+ +I PD + EI KI+ R Sbjct: 310 PGRIDRKIEFSAPDEPARFEILKINSR 336 >sp|P47695|FTSH_MYCGE CELL DIVISION PROTEIN FTSH HOMOLOG >gi|1361466|pir||E64250 cell division protein ftsH - Mycoplasma genitalium >gi|3845051|gb|AAC72477.1| (U39727) cell division protein (ftsH) [Mycoplasma genitalium] Length = 702 Score = 126 bits (314), Expect = 3e-28 Identities = 82/235 (34%), Positives = 125/235 (52%), Gaps = 16/235 (6%) Query: 80 KLKALIKRSTITWNDIGGLREAKKLIAQAIG-----LSIAKSPIEPPQGILLFGPPGTGK 134 K +A + +ST+ + +I GL+E K + + + L A+ P+G++L+GPPGTGK Sbjct: 218 KTQAKLAKSTVKFTNIAGLQEEKHELLEIVDYLKNPLKYAQMGARSPRGVILYGPPGTGK 277 Query: 135 SLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTM 194 +LLA AVA FF S G +K + LF+ A++ +P +IFIDE+DS+ Sbjct: 278 TLLAKAVAGEAGVPFFQSTGSGFEDMLVGVGAKRVRDLFNKAKKAAPCIIFIDEIDSVGS 337 Query: 195 KR----VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRI 248 KR +S + + LLAEMDGF R V+V+ ATN LD+A+L R I Sbjct: 338 KRGRVELSSYSVVEQTLNQLLAEMDGFTSRTG-VVVMAATNRLDVLDDALLRPGRFDRHI 396 Query: 249 YVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRL--YSGREIANVVKLATM 301 + LPD+ I K+H + +S L + KR +SG ++ NV+ AT+ Sbjct: 397 QINLPDIKEREGILKVHAENKNLSSKISLL--DVAKRTPGFSGAQLENVINEATL 449 >gb|AAB63647.1| (AC001645) cell division protein FtsH isolog [Arabidopsis thaliana] Length = 983 Score = 125 bits (311), Expect = 7e-28 Identities = 97/359 (27%), Positives = 173/359 (48%), Gaps = 50/359 (13%) Query: 2 YRLQLLQVQKCQEEFERALSLGHYDKARLIALRCAELLRKIASENLSLSHILLEEAKKWE 61 YR+ +L +K ++++E L + K ++ L E + E Sbjct: 479 YRVVVLNYRKQKKDYEDRLKI-----------------EKAEADERKKMRELEREMEGIE 521 Query: 62 EKAKNVRKRREGKNEY------FDKLKALIKRST-------------ITWNDIGGLREAK 102 E+ + V + KN Y F K A ++R++ + + D+ GL + + Sbjct: 522 EEDEEVEEGTGEKNPYLQMAMQFMKSGARVRRASNKRLPEYLERGVDVKFTDVAGLGKIR 581 Query: 103 KLIAQAI-----GLSIAKSPIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDL 157 + + + G + ++ P GILL GPPG GK+LLA AVA FFS+ AS Sbjct: 582 LELEEIVKFFTHGEMYRRRGVKIPGGILLCGPPGVGKTLLAKAVAGEAGVNFFSISASQF 641 Query: 158 LSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDAARR----MIGTLLAE 213 + Y G + + AL+ AR+ +PSV+FIDE+D++ +R + + + + LL Sbjct: 642 VEIYVGVGASRVRALYQEARENAPSVVFIDELDAVGRERGLIKGSGGQERDATLNQLLVS 701 Query: 214 MDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHY 271 +DGF E + +VI + +TN P LD A++ R +I++P P + +EI ++H R Sbjct: 702 LDGF-EGRGEVITIASTNRPDILDPALVRPGRFDRKIFIPKPGLIGRMEILQVHARKKPM 760 Query: 272 DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELS--DPLRVSTLKGRDLTTR 328 L +A ++ G E+AN+V++A + M+ + EL+ D L+ + ++ R + R Sbjct: 761 AEDLDYMAVASMTDGMVGAELANIVEIAAINMMRDGRTELTTDDLLQAAQIEERGMLDR 819 >gb|AAF47769.1| (AE003478) CG12010 gene product [Drosophila melanogaster] Length = 736 Score = 125 bits (311), Expect = 7e-28 Identities = 88/337 (26%), Positives = 159/337 (47%), Gaps = 49/337 (14%) Query: 42 IASENLSLSHILLEEAKKWEEKAKNVRKRREGKNEYFDKLKALIKRSTITWNDIGGLREA 101 + ++ + HI L+ + + A R + + T + IGG+ Sbjct: 431 LTKDDFDIEHIFLKSLSQTQPSASRSTDVR-------------VSKMTAGFEVIGGMEAL 477 Query: 102 KKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKAS 155 K+ + ++ I +S + P+G+LL+GPPG K+ +A +A + TF + A+ Sbjct: 478 KRTLQVSVLAGIRQSAAFARFGLSLPKGVLLYGPPGCAKTTVAKCLAKEADMTFIATSAA 537 Query: 156 DLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD-----DAARRMIGTL 210 ++ S Y G + + IS +F AR+ +P +IF+DE+DSL +R R++ TL Sbjct: 538 EVYSPYVGCAERFISRIFDTARKNAPCLIFLDEIDSLVGRRTVSSGGGGGQVQLRILSTL 597 Query: 211 LAEMDGF--KERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHL 266 L EM+G + ++V+ ATN P +D+A+L R I+VP PD S + + K+H Sbjct: 598 LTEMNGIVGGGSQQHILVVAATNRPDMIDDALLRPGRFDKLIHVPAPDEKSRLALLKLHS 657 Query: 267 RGI--HYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVSTLKGRD 324 + + H +V L +A + YSG ++ N+ A ++ + RD Sbjct: 658 QRMPFHENVFLQEIAARTDR--YSGADLCNLCNEAAIEAFQ-----------------RD 698 Query: 325 LTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEF 361 + L DF+ + + KS +T+S + Y ++A F Sbjct: 699 FKATEIELQDFEKVLTKQKSSLTQSQIDGYYKFAYRF 735 >dbj|BAB01269.1| (AB023046) cell division protein FtsH-like [Arabidopsis thaliana] Length = 976 Score = 125 bits (311), Expect = 7e-28 Identities = 97/359 (27%), Positives = 173/359 (48%), Gaps = 50/359 (13%) Query: 2 YRLQLLQVQKCQEEFERALSLGHYDKARLIALRCAELLRKIASENLSLSHILLEEAKKWE 61 YR+ +L +K ++++E L + K ++ L E + E Sbjct: 417 YRVVVLNYRKQKKDYEDRLKI-----------------EKAEADERKKMRELEREMEGIE 459 Query: 62 EKAKNVRKRREGKNEY------FDKLKALIKRST-------------ITWNDIGGLREAK 102 E+ + V + KN Y F K A ++R++ + + D+ GL + + Sbjct: 460 EEDEEVEEGTGEKNPYLQMAMQFMKSGARVRRASNKRLPEYLERGVDVKFTDVAGLGKIR 519 Query: 103 KLIAQAI-----GLSIAKSPIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDL 157 + + + G + ++ P GILL GPPG GK+LLA AVA FFS+ AS Sbjct: 520 LELEEIVKFFTHGEMYRRRGVKIPGGILLCGPPGVGKTLLAKAVAGEAGVNFFSISASQF 579 Query: 158 LSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDAARR----MIGTLLAE 213 + Y G + + AL+ AR+ +PSV+FIDE+D++ +R + + + + LL Sbjct: 580 VEIYVGVGASRVRALYQEARENAPSVVFIDELDAVGRERGLIKGSGGQERDATLNQLLVS 639 Query: 214 MDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHY 271 +DGF E + +VI + +TN P LD A++ R +I++P P + +EI ++H R Sbjct: 640 LDGF-EGRGEVITIASTNRPDILDPALVRPGRFDRKIFIPKPGLIGRMEILQVHARKKPM 698 Query: 272 DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELS--DPLRVSTLKGRDLTTR 328 L +A ++ G E+AN+V++A + M+ + EL+ D L+ + ++ R + R Sbjct: 699 AEDLDYMAVASMTDGMVGAELANIVEIAAINMMRDGRTELTTDDLLQAAQIEERGMLDR 757 >emb|CAA56963.1| (X81072) YTA7 [Saccharomyces cerevisiae] Length = 1379 Score = 125 bits (310), Expect = 1e-27 Identities = 94/298 (31%), Positives = 155/298 (51%), Gaps = 26/298 (8%) Query: 63 KAKNVRKRREGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP----- 117 K +N +K+++ K E D L L + ++DIGGL + + + L + Sbjct: 384 KKENTQKKKKKKPEIAD-LDPLGVDMNVNFDDIGGLDNYIDQLKEMVALPLLYPELYQNF 442 Query: 118 -IEPPQGILLFGPPGTGKSLLASAVANSLNA-----TFFSVKASDLLSKYFGESSKLISA 171 I PP+G+L GPPGTGK+L+A A+A S ++ TFF K +D+LSK+ GE+ + + Sbjct: 443 NITPPRGVLFHGPPGTGKTLMARALAASCSSDERKITFFMRKGADILSKWVGEAERQLRL 502 Query: 172 LFSLARQLSPSVIFIDEVDSLTMKRVSLDDAAR-RMIGTLLAEMDGFKERKDKVIVLTAT 230 LF A++ PS+IF DE+D L R S + ++ TLLA MDG + + +VIV+ AT Sbjct: 503 LFEEAKKHQPSIIFFDEIDGLAPVRSSKQEQIHASIVSTLLALMDGM-DNRGQVIVIGAT 561 Query: 231 NAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEA-VKRLY 287 N P +D A+ R Y PLPDV + +I +I R + + + K A + + Y Sbjct: 562 NRPDAVDPALRRPGRFDREFYFPLPDVKARFKILQIQTRKWSSPLSTNFIDKLAFLTKGY 621 Query: 288 SGREIANVVKLATMKMLEEMNPEL---SDPLRVSTLKGRDLTTRPLTLDDFKYAMARI 342 G ++ ++ A + ++ P++ +D L V K + + + DF A+ +I Sbjct: 622 GGADLRSLCTEAALISIQRSFPQIYRSNDKLLVDPSKIK------VKVSDFMLALKKI 673 >gi|6321709 26S proteasome ATPase; Yta7p [Saccharomyces cerevisiae] >gi|1729862|sp|P40340|TBP7_YEAST TAT-BINDING HOMOLOG 7 >gi|2133219|pir||S64603 YTA7 protein - yeast (Saccharomyces cerevisiae) >gi|1323491|emb|CAA97300.1| (Z73055) ORF YGR270w [Saccharomyces cerevisiae] >gi|1556439|emb|CAA69201.1| (Y07893) yta7 [Saccharomyces cerevisiae] Length = 1379 Score = 125 bits (310), Expect = 1e-27 Identities = 94/298 (31%), Positives = 155/298 (51%), Gaps = 26/298 (8%) Query: 63 KAKNVRKRREGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP----- 117 K +N +K+++ K E D L L + ++DIGGL + + + L + Sbjct: 384 KKENTQKKKKKKPEIAD-LDPLGVDMNVNFDDIGGLDNYIDQLKEMVALPLLYPELYQNF 442 Query: 118 -IEPPQGILLFGPPGTGKSLLASAVANSLNA-----TFFSVKASDLLSKYFGESSKLISA 171 I PP+G+L GPPGTGK+L+A A+A S ++ TFF K +D+LSK+ GE+ + + Sbjct: 443 NITPPRGVLFHGPPGTGKTLMARALAASCSSDERKITFFMRKGADILSKWVGEAERQLRL 502 Query: 172 LFSLARQLSPSVIFIDEVDSLTMKRVSLDDAAR-RMIGTLLAEMDGFKERKDKVIVLTAT 230 LF A++ PS+IF DE+D L R S + ++ TLLA MDG + + +VIV+ AT Sbjct: 503 LFEEAKKHQPSIIFFDEIDGLAPVRSSKQEQIHASIVSTLLALMDGM-DNRGQVIVIGAT 561 Query: 231 NAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEA-VKRLY 287 N P +D A+ R Y PLPDV + +I +I R + + + K A + + Y Sbjct: 562 NRPDAVDPALRRPGRFDREFYFPLPDVKARFKILQIQTRKWSSPLSTNFIDKLAFLTKGY 621 Query: 288 SGREIANVVKLATMKMLEEMNPEL---SDPLRVSTLKGRDLTTRPLTLDDFKYAMARI 342 G ++ ++ A + ++ P++ +D L V K + + + DF A+ +I Sbjct: 622 GGADLRSLCTEAALISIQRSFPQIYRSNDKLLVDPSKIK------VKVSDFMLALKKI 673 >emb|CAB58003.1| (AL121800) BACN5I9.i [Drosophila melanogaster] >gi|7290407|gb|AAF45864.1| (AE003427) CG10793 gene product [Drosophila melanogaster] Length = 479 Score = 125 bits (310), Expect = 1e-27 Identities = 75/189 (39%), Positives = 111/189 (58%), Gaps = 19/189 (10%) Query: 80 KLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPIEPPQ----------GILLFGP 129 K L + I W+D+ G + A +LI +A+ +PIE PQ +LL GP Sbjct: 193 KTSILQENIKIKWSDVCGNQRAIELIKEAV-----LTPIEFPQLFAHGLKPWRSLLLHGP 247 Query: 130 PGTGKSLLASAVANSLNA--TFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFID 187 PG+GK+LLA A+ + TFF++ AS ++SK+ GES K++ LF +A + +PSVIF D Sbjct: 248 PGSGKTLLAKALYSETQGQVTFFNITASIMVSKWRGESEKILRVLFHMAAKRAPSVIFFD 307 Query: 188 EVDSLTMKRVSLDD--AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAMLSRLP 245 E++SLT KR D +++R LL +DG + + V VL +TN PWD+DEA L R Sbjct: 308 EIESLTSKRDRATDHESSKRFKNELLQLLDGMEHSLNGVFVLASTNLPWDIDEAFLRRFE 367 Query: 246 IRIYVPLPD 254 ++ V LP+ Sbjct: 368 KKLLVQLPN 376 >emb|CAB58013.1| (AL121800) BACN5I9.gs.8 [Drosophila melanogaster] Length = 545 Score = 125 bits (310), Expect = 1e-27 Identities = 75/189 (39%), Positives = 111/189 (58%), Gaps = 19/189 (10%) Query: 80 KLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPIEPPQ----------GILLFGP 129 K L + I W+D+ G + A +LI +A+ +PIE PQ +LL GP Sbjct: 259 KTSILQENIKIKWSDVCGNQRAIELIKEAV-----LTPIEFPQLFAHGLKPWRSLLLHGP 313 Query: 130 PGTGKSLLASAVANSLNA--TFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFID 187 PG+GK+LLA A+ + TFF++ AS ++SK+ GES K++ LF +A + +PSVIF D Sbjct: 314 PGSGKTLLAKALYSETQGQVTFFNITASIMVSKWRGESEKILRVLFHMAAKRAPSVIFFD 373 Query: 188 EVDSLTMKRVSLDD--AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAMLSRLP 245 E++SLT KR D +++R LL +DG + + V VL +TN PWD+DEA L R Sbjct: 374 EIESLTSKRDRATDHESSKRFKNELLQLLDGMEHSLNGVFVLASTNLPWDIDEAFLRRFE 433 Query: 246 IRIYVPLPD 254 ++ V LP+ Sbjct: 434 KKLLVQLPN 442 >sp|P75120|FTSH_MYCPN CELL DIVISION PROTEIN FTSH HOMOLOG >gi|2146083|pir||S73497 cell division protein ftsH - Mycoplasma pneumoniae (strain ATCC 29342) >gi|1673833|gb|AAB95819.1| (AE000018) cell division protein FtsH [Mycoplasma pneumoniae] Length = 709 Score = 124 bits (309), Expect = 1e-27 Identities = 80/235 (34%), Positives = 127/235 (54%), Gaps = 16/235 (6%) Query: 80 KLKALIKRSTITWNDIGGLREAKKLIAQAIG-----LSIAKSPIEPPQGILLFGPPGTGK 134 K +A + +S++ +++I GL+E K + + + L A+ P+G++L+GPPGTGK Sbjct: 215 KTQAKLAKSSVRFDNIAGLQEEKHELLEIVDYLKNPLKYAQMGARSPRGVILYGPPGTGK 274 Query: 135 SLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTM 194 +LLA AVA FF S G +K + LF+ A++ +P +IFIDE+DS+ Sbjct: 275 TLLAKAVAGEAGVPFFQSTGSGFEDMLVGVGAKRVRDLFNKAKKAAPCIIFIDEIDSVGS 334 Query: 195 KR----VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRI 248 KR +S + + LLAEMDGF R V+V+ ATN LD+A+L R I Sbjct: 335 KRGRVELSSYSVVEQTLNQLLAEMDGFTSRTG-VVVMAATNRLDVLDDALLRPGRFDRHI 393 Query: 249 YVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRL--YSGREIANVVKLATM 301 + LPD+ I ++H + + +S L + KR +SG ++ NV+ AT+ Sbjct: 394 QINLPDIKEREGILQVHAKNKNLSSKISLL--DVAKRTPGFSGAQLENVINEATL 446 >pir||T03904 hypothetical protein F39G3.7 - Caenorhabditis elegans >gi|7511608|pir||T37276 protein PEX6 homolog - Caenorhabditis elegans >gi|7511609|pir||T37307 protein Pex6p homolog - Caenorhabditis elegans >gi|2291210|gb|AAB65332.1| (AF016424) contains similarity to the AAA family of ATPases [Caenorhabditis elegans] >gi|3721554|dbj|BAA33544.1| (AB010968) PEX6 [Caenorhabditis elegans] >gi|4586630|dbj|BAA76440.1| (AB012224) Pex6p homolog [Caenorhabditis elegans] Length = 720 Score = 124 bits (309), Expect = 1e-27 Identities = 91/293 (31%), Positives = 146/293 (49%), Gaps = 17/293 (5%) Query: 37 ELLRKIASENLSLSHILLEEAKKWEEKAKNVRKRREGKNEYFDKLKALI-------KRST 89 +L +A + + LE+ K +K K K + + DK + K Sbjct: 402 KLANHVAKKTSGFTLAELEKLVKNGKKVKIEEKEEKVYEDLIDKRNSNFADAIGAPKIPN 461 Query: 90 ITWNDIGGLREAKKLIAQAIGLSIAKSPIEPPQGILLFGPPGTGKSLLASAVANSLNATF 149 + W D+GGL E K+ + ++I ++ S GI+L+G PG GK+L+A AVA F Sbjct: 462 VRWEDVGGLEETKQTVLESIRTNLFGSRALKRSGIILYGSPGCGKTLIAKAVATEFKIAF 521 Query: 150 FSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDAA---RRM 206 SVK +LL+KY G+S + + +F A+Q SP VIF DE+DSL R D+ R+ Sbjct: 522 LSVKGPELLNKYVGQSEENLRKVFERAKQASPCVIFFDEIDSLAPNRGRNGDSGGVIDRI 581 Query: 207 IGTLLAEMDGFKERK-DKVIVLTATNAPWDLDEAMLS--RLPIRIYV-PLPDVNSAVEIF 262 + LLAE+D KV V+ ATN P LD ++++ R + V P DV S +I Sbjct: 582 VSQLLAELDKLHNSPLTKVFVMGATNRPDLLDNSLMTPGRFDKLVEVKPGEDVESKTKIL 641 Query: 263 KIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSD 313 + R + + DV L +A + +++ SG ++ +++ A M + E + D Sbjct: 642 EAVSRKMRFEEDVDLREIASKVDEKM-SGAQLFSIISNAGMAAIVETIQSIED 693 >gi|11467752 hypothetical chloroplast RF25 [Guillardia theta] >gi|6016057|sp|O78516|FTSH_GUITH CELL DIVISION PROTEIN FTSH HOMOLOG >gi|3603077|gb|AAC35738.1| (AF041468) hypothetical chloroplast RF25 [Guillardia theta] Length = 631 Score = 124 bits (308), Expect = 2e-27 Identities = 80/245 (32%), Positives = 131/245 (52%), Gaps = 19/245 (7%) Query: 73 GKNEYFDKLKALIK---RSTITWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQ 122 G+ F K KA + ++ +T+ND+ G+ EAK+ + + S K P + P+ Sbjct: 150 GQAMNFGKSKARFQMEAKTGVTFNDVAGVDEAKEEFEEVV--SFLKKPERFTAVGAKIPK 207 Query: 123 GILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPS 182 G+LL GPPGTGK+LLA A+A FFS+ S+ + + G + + LF A++ SP Sbjct: 208 GVLLVGPPGTGKTLLAKAIAGEAGVPFFSISGSEFVEMFVGVGASRVRDLFKKAKENSPC 267 Query: 183 VIFIDEVDSLTMKRVS----LDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDE 238 ++FIDE+D++ +R + +D + + LL EMDGF E +I++ ATN LD Sbjct: 268 IVFIDEIDAVGRQRGTGIGGGNDEREQTLNQLLTEMDGF-EGNTGIIIIAATNRVDVLDA 326 Query: 239 AML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVV 296 A+L R ++ V +PDV +EI +H R D+ +S +SG ++AN++ Sbjct: 327 ALLRPGRFDRQVTVDVPDVKGRLEILNVHARNKKLDLSISLELIAKRTPGFSGADLANLL 386 Query: 297 KLATM 301 A + Sbjct: 387 NEAAI 391 >emb|CAA47023.1| (X66400) sug1 [Saccharomyces cerevisiae] >gi|1195528|gb|AAB35417.1| 26S protease subunit S8=SUG1 homolog [human, erythrocytes, Peptide, 405 aa] Length = 405 Score = 123 bits (307), Expect = 2e-27 Identities = 90/254 (35%), Positives = 139/254 (54%), Gaps = 17/254 (6%) Query: 67 VRKRREGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP-------IE 119 + K E K + L + K T++ +GGL + K I + I L + K P I Sbjct: 122 LHKVLENKADPLVSLMMVEKVPDSTYDMVGGLTKQIKEIKEVIELPV-KHPELFESLGIA 180 Query: 120 PPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQL 179 P+G++L+GPPGTGK+LLA AVA+ + F V ++L+ KY GE S+++ LF +AR+ Sbjct: 181 QPKGVILYGPPGTGKTLLARAVAHHTDCKFIRVSGAELVQKYIGEGSRMVRELFVMAREH 240 Query: 180 SPSVIFIDEVDSLTMKRV----SLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWD 235 +PS+IF+DE+DS+ RV D +R + LL ++DGF+ K+ + ++ ATN Sbjct: 241 APSIIFMDEIDSIGSTRVEGSGGGDSEVQRTMLELLNQLDGFETSKN-IKIIMATNRLDI 299 Query: 236 LDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVK-RLYSGREI 292 LD A+L R+ +I P P V + EI +IH R ++ ++ L K A K SG ++ Sbjct: 300 LDPALLRPGRIDRKIEFPPPSVAARAEILRIHSRKMNLTRGIN-LRKVAEKMNGCSGADV 358 Query: 293 ANVVKLATMKMLEE 306 V A M L E Sbjct: 359 KGVCTEAGMYALRE 372 >gi|6321390 ATPase; Rpt6p [Saccharomyces cerevisiae] >gi|1709801|sp|Q01939|PRS8_YEAST 26S PROTEASE REGULATORY SUBUNIT 8 HOMOLOG (SUG1 PROTEIN) (CIM3 PROTEIN) (TAT-BINDING PROTEIN TBY1) >gi|2133183|pir||S64052 26S proteasome regulatory particle chain RPT6 - yeast (Saccharomyces cerevisiae) >gi|172878|gb|AAA35138.1| (L01626) Tat-binding protein [Saccharomyces cerevisiae] >gi|1322539|emb|CAA96750.1| (Z72570) ORF YGL048c [Saccharomyces cerevisiae] Length = 405 Score = 123 bits (307), Expect = 2e-27 Identities = 90/254 (35%), Positives = 139/254 (54%), Gaps = 17/254 (6%) Query: 67 VRKRREGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP-------IE 119 + K E K + L + K T++ +GGL + K I + I L + K P I Sbjct: 122 LHKVLENKADPLVSLMMVEKVPDSTYDMVGGLTKQIKEIKEVIELPV-KHPELFESLGIA 180 Query: 120 PPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQL 179 P+G++L+GPPGTGK+LLA AVA+ + F V ++L+ KY GE S+++ LF +AR+ Sbjct: 181 QPKGVILYGPPGTGKTLLARAVAHHTDCKFIRVSGAELVQKYIGEGSRMVRELFVMAREH 240 Query: 180 SPSVIFIDEVDSLTMKRV----SLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWD 235 +PS+IF+DE+DS+ RV D +R + LL ++DGF+ K+ + ++ ATN Sbjct: 241 APSIIFMDEIDSIGSTRVEGSGGGDSEVQRTMLELLNQLDGFETSKN-IKIIMATNRLDI 299 Query: 236 LDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVK-RLYSGREI 292 LD A+L R+ +I P P V + EI +IH R ++ ++ L K A K SG ++ Sbjct: 300 LDPALLRPGRIDRKIEFPPPSVAARAEILRIHSRKMNLTRGIN-LRKVAEKMNGCSGADV 358 Query: 293 ANVVKLATMKMLEE 306 V A M L E Sbjct: 359 KGVCTEAGMYALRE 372 >prf||1813279A SUG1 gene [Saccharomyces cerevisiae] Length = 400 Score = 123 bits (307), Expect = 2e-27 Identities = 90/254 (35%), Positives = 139/254 (54%), Gaps = 17/254 (6%) Query: 67 VRKRREGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP-------IE 119 + K E K + L + K T++ +GGL + K I + I L + K P I Sbjct: 122 LHKVLENKADPLVSLMMVEKVPDSTYDMVGGLTKQIKEIKEVIELPV-KHPELFESLGIA 180 Query: 120 PPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQL 179 P+G++L+GPPGTGK+LLA AVA+ + F V ++L+ KY GE S+++ LF +AR+ Sbjct: 181 QPKGVILYGPPGTGKTLLARAVAHHTDCKFIRVSGAELVQKYIGEGSRMVRELFVMAREH 240 Query: 180 SPSVIFIDEVDSLTMKRV----SLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWD 235 +PS+IF+DE+DS+ RV D +R + LL ++DGF+ K+ + ++ ATN Sbjct: 241 APSIIFMDEIDSIGSTRVEGSGGGDSEVQRTMLELLNQLDGFETSKN-IKIIMATNRLDI 299 Query: 236 LDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVK-RLYSGREI 292 LD A+L R+ +I P P V + EI +IH R ++ ++ L K A K SG ++ Sbjct: 300 LDPALLRPGRIDRKIEFPPPSVAARAEILRIHSRKMNLTRGIN-LRKVAEKMNGCSGADV 358 Query: 293 ANVVKLATMKMLEE 306 V A M L E Sbjct: 359 KGVCTEAGMYALRE 372 >gb|AAB70882.1| (U77918) spermatogenic cell/sperm-associated Tat-binding protein homolog Sata [Rattus norvegicus] Length = 442 Score = 123 bits (307), Expect = 2e-27 Identities = 81/221 (36%), Positives = 127/221 (56%), Gaps = 17/221 (7%) Query: 76 EYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLF 127 EY ++KA+ +R T ++DIGGL + + + +AI L + I+PP+G+L++ Sbjct: 170 EYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMY 229 Query: 128 GPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFID 187 GPPGTGK+LLA A A ATF + L+ + G+ +KL+ F+LA++ +PS+IFID Sbjct: 230 GPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFID 289 Query: 188 EVDSLTMKRVSLDDA----ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML-- 241 E+D++ KR + A +R + LL +MDGF + +V V+ ATN LD A+L Sbjct: 290 ELDAIGTKRFDSEKAGDREVQRTMLELLNQMDGF-QPNTQVKVIAATNRVDILDPALLRS 348 Query: 242 SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAK 280 RL +I P+P+ + I +IH R + DV LA+ Sbjct: 349 GRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELAR 389 >sp|P34124|PRS8_DICDI 26S PROTEASE REGULATORY SUBUNIT 8 (TAT-BINDING PROTEIN HOMOLOG 10) >gi|422297|pir||JN0610 probable transcription factor DdTBP10 - slime mold (Dictyostelium discoideum) (fragment) >gi|290057|gb|AAA33254.1| (L16579) HIV1 TAT-binding protein [Dictyostelium discoideum] Length = 389 Score = 123 bits (306), Expect = 3e-27 Identities = 91/251 (36%), Positives = 134/251 (53%), Gaps = 19/251 (7%) Query: 79 DKLKALIKRSTI---TWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFG 128 D L +L+K I T++ +GGL + K I + I L I K P I P+G+LL+G Sbjct: 114 DPLVSLMKVEKIPDSTYDMVGGLDKQIKEIKEVIELPI-KHPELFESLGIAQPKGVLLYG 172 Query: 129 PPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDE 188 PPGTGK+LLA AVA+ + TF V S+L+ KY GE S+++ LF +AR+ +PS+IF+DE Sbjct: 173 PPGTGKTLLARAVAHHTDCTFIRVSGSELVQKYIGEGSRMVRELFIMAREHAPSIIFMDE 232 Query: 189 VDSLTMKRVSL-----DDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML-- 241 +DS+ R D +R + LL ++DGF+ K+ + VL TN LD A+L Sbjct: 233 IDSIGSSRGESGSGGGDSEVQRTMLELLNQLDGFESTKN-IKVLMCTNRIDILDPALLRP 291 Query: 242 SRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATM 301 R+ +I P P ++I KIH R ++ ++ SG E+ V A M Sbjct: 292 GRIDRKIEFPNPGDAGRLDILKIHSRKMNLTRGINLKKISDKMNGASGAELKAVCTEAGM 351 Query: 302 KMLEEMNPELS 312 L E +S Sbjct: 352 YALRERRVHVS 362 >pir||A48667 peroxisomal assembly protein 5 - yeast (Pichia pastoris) Length = 1165 Score = 123 bits (305), Expect = 4e-27 Identities = 110/376 (29%), Positives = 177/376 (46%), Gaps = 51/376 (13%) Query: 26 DKARLIALRCAELLRKIASENLSLSHILLEEAKKWEEKAKNVRKR-REGKNEYFDKLKAL 84 + A+ +A+ E L K N+S +++ + ++V K +N++ D + A Sbjct: 754 ENAKTLAVDRVESLAK--HHNVSFENMVYSSGGYIKFTPEDVEKSINTARNKFSDSIGAP 811 Query: 85 IKRSTITWNDIGGLREAKKLIAQAIGL-----SIAKSPIEPPQGILLFGPPGTGKSLLAS 139 + + W D+GGL K I I + + + I+ GIL +GPPGTGK+LLA Sbjct: 812 -RIPNVKWEDVGGLDVVKDEILDTIDMPMKHPELFSNGIKKRSGILFYGPPGTGKTLLAK 870 Query: 140 AVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL 199 A+A + FFSVK +LL+ Y GES + +F AR P V+F DE+DS+ KR + Sbjct: 871 AIATNFALNFFSVKGPELLNMYIGESEANVRKVFQRARDAKPCVVFFDELDSVAPKRGNQ 930 Query: 200 DDAA---RRMIGTLLAEMDGFK--ERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPL 252 D+ R++ LLAE+DG + D V V+ ATN P LDEA+L R +Y+ + Sbjct: 931 GDSGGVMDRIVSQLLAELDGMSGGDGGDGVFVVGATNRPDLLDEALLRPGRFDKMLYLGV 990 Query: 253 PDVNSAVEIF------KIHLRGIHYDVPLSRLAKEAVKRLYSGRE--------------- 291 D + K HL H V L ++A E+ ++G + Sbjct: 991 SDTHEKQSKIMEALSRKFHL---HPSVDLDKVA-ESCPFTFTGADFYALCSDAMLNAMTR 1046 Query: 292 IANVVKLATMKMLEEMNPELSDPLRVSTLKGRD-LTTRP-----LTLDDFKYAMARIKSP 345 IAN V + ++ N EL + +VST D + T+ +TL+DF + + Sbjct: 1047 IANTVD----EKIKRYNEELPEKSQVSTRWWFDNVATKEDIDVLVTLEDFDKSRKELVPS 1102 Query: 346 ITKSDVKKYERWAKEF 361 ++ ++ Y R + F Sbjct: 1103 VSAEELDHYLRVRQNF 1118 >sp|Q25544|PRS8_NAEFO 26S PROTEASE REGULATORY SUBUNIT 8 HOMOLOG (TAT-BINDING PROTEIN HOMOLOG) >gi|1353667|gb|AAB01762.1| (U41812) Tat-binding protein homolog [Naegleria fowleri] Length = 414 Score = 123 bits (305), Expect = 4e-27 Identities = 88/245 (35%), Positives = 133/245 (53%), Gaps = 19/245 (7%) Query: 79 DKLKALIKRSTI---TWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFG 128 D L +L+K + T+ +GGL E K I + I L I K P I P+G++++G Sbjct: 139 DPLVSLMKVEKVPDATYEMVGGLDEQIKEIKEVIELPI-KHPELFESLGIAQPKGVIMYG 197 Query: 129 PPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDE 188 PPGTGK+LLA AVA+ + TF V S+L+ KY GE SK++ LF +AR+ +PS+IF+DE Sbjct: 198 PPGTGKTLLARAVAHHTDCTFIRVSGSELVQKYIGEGSKMVRELFVMAREHAPSIIFMDE 257 Query: 189 VDSLTMKRV-----SLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML-- 241 +DS+ R D +R + LL ++DGF E + ++ ATN LD A+L Sbjct: 258 IDSIGSTRTEGGKGGGDSEVQRTMLELLNQLDGF-ESTQNIKIIMATNRIDILDPALLRP 316 Query: 242 SRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATM 301 R+ +I P P+ + ++I KIH R ++ ++ ++ SG EI A M Sbjct: 317 GRIDRKIEFPNPNELARLDILKIHSRRMNLTRGINLRKIASMLGGASGAEIKATCTEAGM 376 Query: 302 KMLEE 306 L E Sbjct: 377 FALRE 381 >sp|O42586|PRSB_XENLA 26S PROTEASE REGULATORY SUBUNIT 6A (TAT-BINDING PROTEIN 10) (TBP-10) >gi|2648045|emb|CAA71486.1| (Y10460) TBP10 protein [Xenopus laevis] Length = 404 Score = 123 bits (305), Expect = 4e-27 Identities = 81/221 (36%), Positives = 127/221 (56%), Gaps = 17/221 (7%) Query: 76 EYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLF 127 EY ++KA+ +R T ++DIGGL + + + +AI L + I+PP+G+L++ Sbjct: 132 EYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMY 191 Query: 128 GPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFID 187 GPPGTGK+LLA A A ATF + L+ + G+ +KL+ FSLA++ +PS+IFID Sbjct: 192 GPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFSLAKEKAPSIIFID 251 Query: 188 EVDSLTMKRVSLDDA----ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML-- 241 E+D++ KR + A +R + LL ++DGF + +V V+ ATN LD A+L Sbjct: 252 ELDAIGNKRFDSEKAGDREVQRTMLELLNQLDGF-QPTTQVKVIAATNRVDILDPALLRS 310 Query: 242 SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAK 280 RL +I P+P+ + I +IH R + DV LA+ Sbjct: 311 GRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELAR 351 >pir||D82934 ATP-dependent zinc metallopeptidase, cell division protein UU105 [imported] - Ureaplasma urealyticum >gi|6899060|gb|AAF30511.1|AE002110_9 (AE002110) ATP-dependent zinc metallopeptidase - cell division protein [Ureaplasma urealyticum] Length = 721 Score = 123 bits (305), Expect = 4e-27 Identities = 78/233 (33%), Positives = 126/233 (53%), Gaps = 13/233 (5%) Query: 79 DKLKALIKRSTITWNDIGGLREAKKLIAQAIGL-----SIAKSPIEPPQGILLFGPPGTG 133 +K A + +S + ++D+ G+ E K+ + + + + P+G++L+GPPGTG Sbjct: 225 NKANAKLTKSGVRFSDVAGIAEVKEELIEIVDFLKEPKKYVAAGARIPKGVMLYGPPGTG 284 Query: 134 KSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLT 193 K+L+A AVA N FF S + G ++ + LF AR+ +P++IFIDE+DS+ Sbjct: 285 KTLIAKAVAGEANVPFFQTTGSSFEDTFVGVGARRVRELFEKARKSAPAIIFIDEIDSVA 344 Query: 194 MKR-VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYV 250 KR SL + I LL+E+DGF + VIV+ ATN LD+A+L R +I V Sbjct: 345 KKRGNSLTAVQDQTINQLLSELDGF-DTSSGVIVMAATNRLDTLDDAILRPGRFDRQISV 403 Query: 251 PLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANVVKLATM 301 LPD+ +I +IH R + V L +A+ +SG ++ NV+ A + Sbjct: 404 NLPDILEREQILRIHSRNKNLSAKVSLEDIARRTAG--FSGAQLENVLNEAAL 454 >gi|4506211 proteasome (prosome, macropain) 26S subunit, ATPase, 3 [Homo sapiens] >gi|107855|pir||A34832 Tat-binding protein-1 - human >gi|338700|gb|AAA36666.1| (M34079) tat binding protein-1 (tbp-1) [Homo sapiens] Length = 404 Score = 122 bits (304), Expect = 5e-27 Identities = 80/221 (36%), Positives = 127/221 (57%), Gaps = 17/221 (7%) Query: 76 EYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLF 127 EY ++KA+ +R T ++DIGGL + + + +AI L + I+PP+G+L++ Sbjct: 132 EYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMY 191 Query: 128 GPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFID 187 GPPGTGK+LLA A A ATF + L+ + G+ +KL+ F+LA++ +PS+IFID Sbjct: 192 GPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFID 251 Query: 188 EVDSLTMKRVSLDDA----ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML-- 241 E+D++ KR + A +R + LL ++DGF + +V V+ ATN LD A+L Sbjct: 252 ELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGF-QPNTQVKVIAATNRVDILDPALLRS 310 Query: 242 SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAK 280 RL +I P+P+ + I +IH R + DV LA+ Sbjct: 311 GRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELAR 351 >gb|AAB24840.1| Tat binding protein 1, TBP-1=transcriptional activator [human, Peptide, 439 aa] Length = 439 Score = 122 bits (304), Expect = 5e-27 Identities = 80/221 (36%), Positives = 127/221 (57%), Gaps = 17/221 (7%) Query: 76 EYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLF 127 EY ++KA+ +R T ++DIGGL + + + +AI L + I+PP+G+L++ Sbjct: 167 EYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMY 226 Query: 128 GPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFID 187 GPPGTGK+LLA A A ATF + L+ + G+ +KL+ F+LA++ +PS+IFID Sbjct: 227 GPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFID 286 Query: 188 EVDSLTMKRVSLDDA----ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML-- 241 E+D++ KR + A +R + LL ++DGF + +V V+ ATN LD A+L Sbjct: 287 ELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGF-QPNTQVKVIAATNRVDILDPALLRS 345 Query: 242 SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAK 280 RL +I P+P+ + I +IH R + DV LA+ Sbjct: 346 GRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELAR 386 >sp|P33289|PEX6_PICPA PEROXISOME BIOSYNTHESIS PROTEIN PAS5 (PEROXIN-6) >gi|396147|emb|CAA80278.1| (Z22556) PAS5 [Pichia pastoris] Length = 1165 Score = 122 bits (304), Expect = 5e-27 Identities = 110/376 (29%), Positives = 177/376 (46%), Gaps = 51/376 (13%) Query: 26 DKARLIALRCAELLRKIASENLSLSHILLEEAKKWEEKAKNVRKR-REGKNEYFDKLKAL 84 + A+ +A+ E L K N+S +++ + ++V K +N++ D + A Sbjct: 754 ENAKTLAVDRVESLAK--HHNVSFENMVYSSGGYIKFTPEDVEKSINTARNKFSDSIGAP 811 Query: 85 IKRSTITWNDIGGLREAKKLIAQAIGL-----SIAKSPIEPPQGILLFGPPGTGKSLLAS 139 + + W D+GGL K I I + + + I+ GIL +GPPGTGK+LLA Sbjct: 812 -RIPNVKWEDVGGLDVVKDEILDTIDMPMKHPELFSNGIKKRSGILFYGPPGTGKTLLAK 870 Query: 140 AVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL 199 A+A + FFSVK +LL+ Y GES + +F AR P V+F DE+DS+ KR + Sbjct: 871 AIATNFALNFFSVKGPELLNMYIGESEANVRKVFQRARDAKPCVVFFDELDSVAPKRGNQ 930 Query: 200 DDA---ARRMIGTLLAEMDGFK--ERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPL 252 D+ R++ LLAE+DG + D V V+ ATN P LDEA+L R +Y+ + Sbjct: 931 GDSEGVMDRIVSQLLAELDGMSGGDGGDGVFVVGATNRPDLLDEALLRPGRFDKMLYLGV 990 Query: 253 PDVNSAVEIF------KIHLRGIHYDVPLSRLAKEAVKRLYSGRE--------------- 291 D + K HL H V L ++A E+ ++G + Sbjct: 991 SDTHEKQSKIMEALSRKFHL---HPSVDLDKVA-ESCPFTFTGADFYALCSDAMLNAMTR 1046 Query: 292 IANVVKLATMKMLEEMNPELSDPLRVSTLKGRD-LTTRP-----LTLDDFKYAMARIKSP 345 IAN V + ++ N EL + +VST D + T+ +TL+DF + + Sbjct: 1047 IANTVD----EKIKRYNEELPEKSQVSTRWWFDNVATKEDIDVLVTLEDFDKSRKELVPS 1102 Query: 346 ITKSDVKKYERWAKEF 361 ++ ++ Y R + F Sbjct: 1103 VSAEELDHYLRVRQNF 1118 >sp|P17980|PRSA_HUMAN 26S PROTEASE REGULATORY SUBUNIT 6A (TAT-BINDING PROTEIN 1) (TBP-1) (PROTEASOME SUBUNIT P50) Length = 439 Score = 122 bits (304), Expect = 5e-27 Identities = 80/221 (36%), Positives = 127/221 (57%), Gaps = 17/221 (7%) Query: 76 EYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLF 127 EY ++KA+ +R T ++DIGGL + + + +AI L + I+PP+G+L++ Sbjct: 167 EYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMY 226 Query: 128 GPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFID 187 GPPGTGK+LLA A A ATF + L+ + G+ +KL+ F+LA++ +PS+IFID Sbjct: 227 GPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFID 286 Query: 188 EVDSLTMKRVSLDDA----ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML-- 241 E+D++ KR + A +R + LL ++DGF + +V V+ ATN LD A+L Sbjct: 287 ELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGF-QPNTQVKVIAATNRVDILDPALLRS 345 Query: 242 SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAK 280 RL +I P+P+ + I +IH R + DV LA+ Sbjct: 346 GRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELAR 386 >sp|Q63569|PRSA_RAT 26S PROTEASE REGULATORY SUBUNIT 6A (TAT-BINDING PROTEIN 1) (TBP-1) (SPERMATOGENIC CELL/SPERM-ASSOCIATED TAT-BINDING PROTEIN HOMOLOG SATA) >gi|1395184|dbj|BAA11939.1| (D83522) proteasomal ATPase (rat TBP1) [Rattus norvegicus] Length = 439 Score = 122 bits (304), Expect = 5e-27 Identities = 80/221 (36%), Positives = 127/221 (57%), Gaps = 17/221 (7%) Query: 76 EYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLF 127 EY ++KA+ +R T ++DIGGL + + + +AI L + I+PP+G+L++ Sbjct: 167 EYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMY 226 Query: 128 GPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFID 187 GPPGTGK+LLA A A ATF + L+ + G+ +KL+ F+LA++ +PS+IFID Sbjct: 227 GPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFID 286 Query: 188 EVDSLTMKRVSLDDA----ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML-- 241 E+D++ KR + A +R + LL ++DGF + +V V+ ATN LD A+L Sbjct: 287 ELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGF-QPNTQVKVIAATNRVDILDPALLRS 345 Query: 242 SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAK 280 RL +I P+P+ + I +IH R + DV LA+ Sbjct: 346 GRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELAR 386 >sp|P46470|PRS8_XENLA 26S PROTEASE REGULATORY SUBUNIT 8 (SUG1 HOMOLOG) (XSUG1) >gi|1877414|emb|CAA57512.1| (X81986) XSUG1 [Xenopus laevis] Length = 461 Score = 122 bits (304), Expect = 5e-27 Identities = 89/285 (31%), Positives = 147/285 (51%), Gaps = 33/285 (11%) Query: 91 TWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQGILLFGPPGTGKSLLASAVAN 143 T+ IGGL + K I + I L + K P I P+G+LL+GPPGTGK+LLA AVA+ Sbjct: 142 TYEMIGGLDKQIKEIKEVIELPV-KHPEHFEALGIAQPKGVLLYGPPGTGKTLLARAVAH 200 Query: 144 SLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMK---RVSLD 200 + TF V S+L+ K+ GE ++++ LF +AR+ +PS+IF+DE+DS+ + D Sbjct: 201 HTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSRLEGGSGGD 260 Query: 201 DAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSA 258 +R + LL ++DGF+ K+ + V+ ATN LD A+L R+ +I P P+ + Sbjct: 261 SEVQRTMLELLNQLDGFEATKN-IKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEAR 319 Query: 259 VEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELSDPLRVS 318 ++I KIH R ++ ++ + SG E+ V A M L E Sbjct: 320 LDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVH-------- 371 Query: 319 TLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEFAI 363 +T +DF+ A+A++ ++ ++ + W F + Sbjct: 372 -----------VTQEDFEMAVAKVMQKDSEKNMSIKKLWKCFFLV 405 >sp|O42587|PRSA_XENLA 26S PROTEASE REGULATORY SUBUNIT 6A (TAT-BINDING PROTEIN 6) (TBP-6) >gi|2648047|emb|CAA71487.1| (Y10461) TBP6 protein [Xenopus laevis] Length = 405 Score = 122 bits (304), Expect = 5e-27 Identities = 80/221 (36%), Positives = 127/221 (57%), Gaps = 17/221 (7%) Query: 76 EYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLF 127 EY ++KA+ +R T ++DIGGL + + + +AI L + I+PP+G+L++ Sbjct: 151 EYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMY 210 Query: 128 GPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFID 187 GPPGTGK+LLA A A ATF + L+ + G+ +KL+ F+LA++ +PS+IFID Sbjct: 211 GPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFID 270 Query: 188 EVDSLTMKRVSLDDA----ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML-- 241 E+D++ KR + A +R + LL ++DGF+ +V V+ ATN LD A+L Sbjct: 271 ELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNM-QVKVIAATNRVDILDPALLRS 329 Query: 242 SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAK 280 RL +I P+P+ + I +IH R + DV LA+ Sbjct: 330 GRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELAR 370 >gi|11437005 proteasome (prosome, macropain) 26S subunit, ATPase, 3 [Homo sapiens] Length = 423 Score = 122 bits (304), Expect = 5e-27 Identities = 80/221 (36%), Positives = 127/221 (57%), Gaps = 17/221 (7%) Query: 76 EYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLF 127 EY ++KA+ +R T ++DIGGL + + + +AI L + I+PP+G+L++ Sbjct: 151 EYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMY 210 Query: 128 GPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFID 187 GPPGTGK+LLA A A ATF + L+ + G+ +KL+ F+LA++ +PS+IFID Sbjct: 211 GPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFID 270 Query: 188 EVDSLTMKRVSLDDA----ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML-- 241 E+D++ KR + A +R + LL ++DGF + +V V+ ATN LD A+L Sbjct: 271 ELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGF-QPNTQVKVIAATNRVDILDPALLRS 329 Query: 242 SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAK 280 RL +I P+P+ + I +IH R + DV LA+ Sbjct: 330 GRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELAR 370 >gi|11465515 unknown; cell division protein [Cyanidium caldarium] >gi|7446582|pir||T11990 cell division protein - red alga (Cyanidium caldarium) chloroplast >gi|2465738|gb|AAB82667.1| (AF022186) unknown; cell division protein [Cyanidium caldarium] Length = 614 Score = 122 bits (303), Expect = 6e-27 Identities = 82/251 (32%), Positives = 135/251 (53%), Gaps = 19/251 (7%) Query: 78 FDKLKA---LIKRSTITWNDIGGLREAKKLIAQAIGL-----SIAKSPIEPPQGILLFGP 129 F K KA + ++ I + D+ G+ EAK+ + + + P+G+LL GP Sbjct: 153 FGKAKARFHMEAKTGIVFEDVAGIEEAKEELQEIVAFLKDSRKFTNVGATIPKGVLLVGP 212 Query: 130 PGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEV 189 PGTGK+LLA A+A +A FFS+ S+ + + G + + LF A++ +P ++FIDE+ Sbjct: 213 PGTGKTLLAKAIAGEASAPFFSISGSEFVEMFVGVGASRVRDLFKKAKEKAPCIVFIDEI 272 Query: 190 DSLTMKR-VSL---DDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SR 243 D++ +R V + +D + + LL EMDGF VIV+ ATN LD A+L R Sbjct: 273 DAVGRQRGVGIGGGNDEREQTLNQLLTEMDGF-SGDTGVIVVAATNRIDVLDSALLRPGR 331 Query: 244 LPIRIYVPLPDVNSAVEIFKIH--LRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATM 301 +I V LP++N + I K+H + IH DV L +A+ +SG ++AN++ A + Sbjct: 332 FDRQIMVSLPNINGRLAILKVHSKKKKIHKDVLLEVIARRTPG--FSGADLANLLNEAAI 389 Query: 302 KMLEEMNPELS 312 + E++ Sbjct: 390 LTVRRGKVEIT 400 >gi|6679503 proteasome (prosome, macropain) 26S subunit, ATPase 3; Tat binding protein 1 [Mus musculus] >gi|3510277|dbj|BAA32559.1| (D49686) Tat binding protein-1 [Mus musculus] >gi|10697242|dbj|BAB16347.1| (AB040858) proteasomal ATPase [Mus musculus] Length = 442 Score = 121 bits (301), Expect = 1e-26 Identities = 79/221 (35%), Positives = 127/221 (56%), Gaps = 17/221 (7%) Query: 76 EYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLF 127 +Y ++KA+ +R T ++DIGGL + + + +AI L + I+PP+G+L++ Sbjct: 170 DYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMY 229 Query: 128 GPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFID 187 GPPGTGK+LLA A A ATF + L+ + G+ +KL+ F+LA++ +PS+IFID Sbjct: 230 GPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFID 289 Query: 188 EVDSLTMKRVSLDDA----ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML-- 241 E+D++ KR + A +R + LL ++DGF + +V V+ ATN LD A+L Sbjct: 290 ELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGF-QPNTQVKVIAATNRVDILDPALLRS 348 Query: 242 SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAK 280 RL +I P+P+ + I +IH R + DV LA+ Sbjct: 349 GRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELAR 389 >emb|CAB51029.1| (AJ243808) metalloprotease FtsH [Bradyrhizobium japonicum] Length = 640 Score = 121 bits (301), Expect = 1e-26 Identities = 80/245 (32%), Positives = 131/245 (52%), Gaps = 19/245 (7%) Query: 73 GKNEYFDKLKALI---KRSTITWNDIGGLREAKKLIAQAIGLSIAKSPIEP-----PQGI 124 GK F K +A + +T+ D+ G+ EAK+ + + + + P+G+ Sbjct: 133 GKAMGFGKSRAKMLTEAHGRVTFEDVAGVDEAKQDLQEIVEFLRDPGKFQRLGGRIPRGV 192 Query: 125 LLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVI 184 LL GPPGTGK+L+A AVA N FF++ SD + + G + + +F A++ +P +I Sbjct: 193 LLVGPPGTGKTLIARAVAGEANVPFFTISGSDFVEMFVGVGASRVRDMFEQAKKNAPCII 252 Query: 185 FIDEVDSLTMKRVS----LDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM 240 FIDE+D++ R + +D + + LL EMDGF E + VI++ ATN P LD A+ Sbjct: 253 FIDEIDAVGRHRGAGLGGGNDEREQTLNQLLVEMDGF-EANEGVILIAATNRPDVLDPAL 311 Query: 241 L--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHY--DVPLSRLAKEAVKRLYSGREIANVV 296 L R ++ VP PDV +I K+H+R + D+ L +A+ +SG ++ N+V Sbjct: 312 LRPGRFDRQVVVPNPDVVGREQILKVHVRKVPLAPDINLKTIARGTPG--FSGADLMNLV 369 Query: 297 KLATM 301 A + Sbjct: 370 NEAAL 374 >sp|P71377|FTH1_HAEIN CELL DIVISION PROTEIN FTSH HOMOLOG 1 >gi|1574793|gb|AAC22979.1| (U32812) cell division protein (ftsH) [Haemophilus influenzae Rd] Length = 635 Score = 120 bits (299), Expect = 2e-26 Identities = 81/245 (33%), Positives = 128/245 (52%), Gaps = 19/245 (7%) Query: 73 GKNEYFDKLKALIKRST---ITWNDIGGLREAKKLIAQAIGLSIAKSPIEP-----PQGI 124 GK F K +A + +T+ D+ G EAK+ + + + + + P+GI Sbjct: 128 GKAMSFGKSRAKMLNQDQIKVTFADVAGCDEAKEEVGEIVDFLRDPNKFQNLGGKIPKGI 187 Query: 125 LLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVI 184 L+ GPPGTGK+LLA A+A FF++ SD + + G + + +F A++ +P +I Sbjct: 188 LMVGPPGTGKTLLARAIAGEAKVPFFTISGSDFVEMFVGVGASRVRDMFEQAKKNAPCLI 247 Query: 185 FIDEVDSLTMKRVS----LDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM 240 FIDE+D++ +R + D + + +L EMDGF D VIV+ ATN P LD A+ Sbjct: 248 FIDEIDAVGRQRGAGLGGGHDEREQTLNQMLVEMDGF-SGNDGVIVIAATNRPDVLDPAL 306 Query: 241 L--SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANVV 296 R ++ V LPDV +I K+H+R + DV LA+ YSG ++AN+V Sbjct: 307 TRPGRFDRQVVVGLPDVKGREQILKVHMRKVSVAQDVDAMTLARGTPG--YSGADLANLV 364 Query: 297 KLATM 301 A + Sbjct: 365 NEAAL 369 >gb|AAB60775.1| (AC000375) Similar to Xenopus TER ATPase (gb|X54240). [Arabidopsis thaliana] Length = 330 Score = 120 bits (299), Expect = 2e-26 Identities = 81/246 (32%), Positives = 132/246 (52%), Gaps = 26/246 (10%) Query: 119 EPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQ 178 +P GILLFGP GTGK++LA AVA A ++ +S++F E K + A+FSLA + Sbjct: 93 QPCNGILLFGPSGTGKTMLAKAVATEAGANLINMS----MSRWFSEGEKYVKAVFSLASK 148 Query: 179 LSPSVIFIDEVDSLTMKRVSLDDAARRMIGTLLAEMDGFK-ERKDKVIVLTATNAPWDLD 237 +SPS+IF+DEV+S+ + R L + + DG + K++V+VL ATN P+DLD Sbjct: 149 ISPSIIFLDEVESM-LHRYRL-----KTKNEFIINWDGLRTNEKERVLVLAATNRPFDLD 202 Query: 238 EAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVK 297 EA++ RLP R+ V LPD S +I K+ L+KE + + E+A++ Sbjct: 203 EAVIRRLPHRLMVGLPDARSRSKILKV------------ILSKEDLSPDFDIDEVASMTN 250 Query: 298 LATMKMLEEMNPELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVK--KYE 355 + L+E + +++ RV R L ++DF+ A+ + I+ V Sbjct: 251 GYSGNDLKERDAAVAEG-RVPPAGSGGSDLRVLKMEDFRNALELVSMSISSKSVNMTALR 309 Query: 356 RWAKEF 361 +W +++ Sbjct: 310 QWNEDY 315 >pir||D75502 cell division protein FtsH - Deinococcus radiodurans (strain R1) >gi|6458277|gb|AAF10160.1|AE001916_6 (AE001916) cell division protein FtsH [Deinococcus radiodurans] Length = 618 Score = 120 bits (299), Expect = 2e-26 Identities = 82/226 (36%), Positives = 118/226 (51%), Gaps = 22/226 (9%) Query: 67 VRKRREGKNEY---FDKLKALI---KRSTITWNDIGGLREAKKLIAQAIGLSIAKSP--- 117 VR R G N+ F K KA I + +T+ D+ G EAK+ + + + + P Sbjct: 122 VRSRNGGNNDAASSFGKSKAAIISEGQIKLTFADVAGCDEAKQDLQEVV--EFLRQPEKY 179 Query: 118 ----IEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALF 173 P+G+LL GPPG+GK+LLA AVA +FS+ SD + + G + + LF Sbjct: 180 HQLGARIPRGVLLVGPPGSGKTLLAKAVAGEAKVPYFSISGSDFVEMFVGVGAARVRDLF 239 Query: 174 SLARQLSPSVIFIDEVDSLTMKR----VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTA 229 AR+ SP ++FIDE+D++ KR +D + + LL EMDGF +D VI+L A Sbjct: 240 EQARKASPCIVFIDEIDAVGRKRGMNIQGGNDEREQTLNQLLVEMDGFGSGQD-VIILAA 298 Query: 230 TNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDV 273 TN P LD A+L R ++ V PDV +I +IH R DV Sbjct: 299 TNRPDVLDAALLRPGRFDRQVVVDAPDVRGREQILRIHSRKKPLDV 344 >pir||T33155 hypothetical protein F56H1.4 - Caenorhabditis elegans >gi|3193161|gb|AAC19196.1| (AF067618) contains similarity to the AAA family of ATPases (Pfam; AAA, score; 259.07); most similar to human probable 26S protease subunit TBP-1 (SW:P17980) [Caenorhabditis elegans] Length = 430 Score = 120 bits (297), Expect = 3e-26 Identities = 75/221 (33%), Positives = 128/221 (56%), Gaps = 17/221 (7%) Query: 76 EYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLF 127 EY ++KA+ +R T ++DIGG + + + +A+ L + I PP+G+L++ Sbjct: 158 EYDSRVKAMEVDERPTEQYSDIGGCDKQIQELIEAVVLPMTHKDRFVNLGIHPPKGVLMY 217 Query: 128 GPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFID 187 GPPGTGK+++A AVA +TF + L+ + G+ +KL+ F+LA++ +P++IFID Sbjct: 218 GPPGTGKTMMARAVAAQTKSTFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPAIIFID 277 Query: 188 EVDSLTMKRVSLDDA----ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML-- 241 E+D++ KR + A +R + LL ++DGF + D + V+ ATN LD A+L Sbjct: 278 ELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGF-QPNDDIKVIAATNRIDVLDPALLRS 336 Query: 242 SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAK 280 RL +I +P P+ ++ I +IH R ++ DV LA+ Sbjct: 337 GRLDRKIELPHPNEDARARIMQIHSRKMNVNKDVNFEELAR 377 >gb|AAD25809.1|AC006550_17 (AC006550) Belongs to PF|00004 ATPases associated with various cellular activities. [Arabidopsis thaliana] Length = 983 Score = 119 bits (295), Expect = 6e-26 Identities = 89/296 (30%), Positives = 143/296 (48%), Gaps = 30/296 (10%) Query: 86 KRSTITWNDIGGLREAKKLIAQAIGLSIA-----KSPIEPPQGILLFGPPGTGKSLLASA 140 K + W+D+GGL + K I + L + S + G+LL+GPPGTGK+LLA A Sbjct: 693 KVPNVKWDDVGGLEDVKTSILDTVQLPLLHKDLFSSGLRKRSGVLLYGPPGTGKTLLAKA 752 Query: 141 VANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD 200 VA + F SVK +L++ Y GES K + +F AR P VIF DE+DSL R + Sbjct: 753 VATECSLNFLSVKGPELINMYIGESEKNVRDIFEKARSARPCVIFFDELDSLAPARGASG 812 Query: 201 DAA---RRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPL-PD 254 D+ R++ +LAE+DG + + ++ A+N P +D A+L R +YV + D Sbjct: 813 DSGGVMDRVVSQMLAEIDGLSDSSQDLFIIGASNRPDLIDPALLRPGRFDKLLYVGVNAD 872 Query: 255 VNSAVEIFKIHLR--GIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELS 312 + + K R + DV L +AK+ ++G ++ + A + + Sbjct: 873 ASYRERVLKALTRKFKLSEDVSLYSVAKKC-PSTFTGADMYALCADAWFQAAKR------ 925 Query: 313 DPLRVSTLKGRDLTTRPLTLD-------DFKYAMARIKSPITKSDVKKYERWAKEF 361 +VS D+ T D DF AM ++ ++ +++KKYE +F Sbjct: 926 ---KVSKSDSGDMPTEEDDPDSVVVEYVDFIKAMDQLSPSLSITELKKYEMLRDQF 978 >gb|AAD52812.1|AF129874_1 (AF129874) peroxin-6 [Pichia angusta] Length = 1135 Score = 118 bits (294), Expect = 7e-26 Identities = 91/252 (36%), Positives = 130/252 (51%), Gaps = 22/252 (8%) Query: 72 EGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGIL 125 + +N++ D + A + + W D+GGL K I I + + K P ++ GIL Sbjct: 793 DARNKFSDMIGAP-RIPDVKWEDVGGLDVVKDEILDTIEMPL-KHPELFSKGMKKRSGIL 850 Query: 126 LFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIF 185 +GPPGTGK+LLA A+A + FFSVK +LL+ Y GES + +F AR P VIF Sbjct: 851 FYGPPGTGKTLLAKAIATNFALNFFSVKGPELLNMYIGESEANVRRVFQKARDAKPCVIF 910 Query: 186 IDEVDSLTMKRVSLDDAA---RRMIGTLLAEMDGFK--ERKDKVIVLTATNAPWDLDEAM 240 DE+DS+ KR + D+ R++ LLAE+DG E D V V+ ATN P LDEA+ Sbjct: 911 FDELDSVAPKRGNQGDSGGVMDRIVSQLLAELDGMSGAEGGDGVFVVGATNRPDLLDEAL 970 Query: 241 L--SRLPIRIYVPLPDVN-SAVEIFKIHLRGIHYD--VPLSRLAKEAVKRLYSGREIANV 295 L R +Y+ + D + +I + R D V L R+A E Y+G A+ Sbjct: 971 LRPGRFDKMLYLGIADTHEKQAKIIQALTRKFQLDPSVDLGRIA-ETCPFTYTG---ADF 1026 Query: 296 VKLATMKMLEEM 307 L + ML M Sbjct: 1027 YALCSDAMLNAM 1038 >gi|11465793 hypothetical chloroplast ORF 25. [Porphyra purpurea] >gi|1706926|sp|P51327|FTSH_PORPU CELL DIVISION PROTEIN FTSH HOMOLOG >gi|2147534|pir||S73248 hypothetical protein 25 - red alga (Porphyra purpurea) chloroplast >gi|1276793|gb|AAC08213.1| (U38804) hypothetical chloroplast ORF 25. [Porphyra purpurea] Length = 628 Score = 118 bits (293), Expect = 1e-25 Identities = 77/246 (31%), Positives = 131/246 (52%), Gaps = 21/246 (8%) Query: 73 GKNEYFDKLKALIK---RSTITWNDIGGLREAKKLIAQAIGL-----SIAKSPIEPPQGI 124 G+ F K KAL + ++ + +ND+ G+ EAK+ + + S + P+G+ Sbjct: 150 GQAMSFGKSKALFQMEAKTGVVFNDVAGVEEAKEEFQEVVTFLKQPESFTAVGAKIPKGV 209 Query: 125 LLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVI 184 LL GPPGTGK+LLA A+A FFS+ S+ + + G + + LF A+ +P ++ Sbjct: 210 LLVGPPGTGKTLLAKAIAGEAGVPFFSISGSEFVEMFVGVGASRVRDLFKKAKDNAPCIV 269 Query: 185 FIDEVDSLTMKRVS----LDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAM 240 FIDE+D++ +R + +D + + LL EMDGF E VIV+ ATN LD A+ Sbjct: 270 FIDEIDAVGRQRGTGVGGGNDEREQTLNQLLTEMDGF-EGNTGVIVIAATNRADILDSAL 328 Query: 241 L--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRL---YSGREIANV 295 L R ++ V +PD + I ++H + + S+++ E + R +SG ++AN+ Sbjct: 329 LRPGRFDRQVSVDVPDFRGRLAILEVHAKNKKME---SKVSLETIARRTPGFSGADLANL 385 Query: 296 VKLATM 301 + A + Sbjct: 386 LNEAAI 391 >pir||T44596 26S proteasome regulatory complex chain p50 [imported] - fruit fly (Drosophila melanogaster) >gi|5679018|gb|AAD46823.1|AF160882_1 (AF160882) BcDNA.GH12068 [Drosophila melanogaster] >gi|6434948|gb|AAF08386.1|AF145305_1 (AF145305) 26S proteasome regulatory complex subunit p50 [Drosophila melanogaster] >gi|7301041|gb|AAF56177.1| (AE003744) Rpt5 gene product [Drosophila melanogaster] Length = 428 Score = 118 bits (293), Expect = 1e-25 Identities = 77/221 (34%), Positives = 124/221 (55%), Gaps = 17/221 (7%) Query: 76 EYFDKLKALI--KRSTITWNDIGGLREAKKLIAQAIGLSIAKSP------IEPPQGILLF 127 EY ++KA+ +R T ++DIGGL + + + +A+ L + I PP+G+LL+ Sbjct: 156 EYDARVKAMEVDERPTEQYSDIGGLDKQIQELIEAVVLPMTHKEKFKNLGIHPPKGVLLY 215 Query: 128 GPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFID 187 GPPGTGK+LLA A A +TF + L+ + G+ +KL+ F+LA++ +P++IFID Sbjct: 216 GPPGTGKTLLARACAAQTKSTFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPAIIFID 275 Query: 188 EVDSLTMKRVSLDDA----ARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML-- 241 E+D++ KR + A +R + LL ++DGF D + V+ ATN LD A+L Sbjct: 276 ELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFSSTAD-IKVIAATNRVDILDPALLRS 334 Query: 242 SRLPIRIYVPLPDVNSAVEIFKIHLR--GIHYDVPLSRLAK 280 RL +I P P+ + I +IH R + DV L++ Sbjct: 335 GRLDRKIEFPHPNEEARARIMQIHSRKMNVSNDVNFEELSR 375 >sp|P73179|FTH2_SYNY3 CELL DIVISION PROTEIN FTSH HOMOLOG 2 >gi|7446575|pir||S75291 cell division protein ftsH-3 - Synechocystis sp. (strain PCC 6803) >gi|1652282|dbj|BAA17205.1| (D90904) cell division protein FtsH [Synechocystis sp.] Length = 665 Score = 118 bits (292), Expect = 1e-25 Identities = 79/247 (31%), Positives = 133/247 (52%), Gaps = 23/247 (9%) Query: 73 GKNEYFDKLKALIK---RSTITWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQ 122 G+ F K KA + ++ + ++D+ G+ EAK+ + + + + K P + P+ Sbjct: 188 GQAMSFGKSKARFQMEAKTGVGFDDVAGIDEAKEELQEVV--TFLKQPEKFTAIGAKIPR 245 Query: 123 GILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPS 182 G+LL GPPGTGK+LLA A+A FFS+ S+ + + G + + LF A++ +P Sbjct: 246 GVLLIGPPGTGKTLLAKAIAGEAGVPFFSISGSEFVEMFVGVGASRVRDLFKKAKENAPC 305 Query: 183 VIFIDEVDSLTMKR----VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDE 238 ++FIDE+D++ +R +D + + LL EMDGF E +IV+ ATN P LD Sbjct: 306 LVFIDEIDAVGRQRGVGYGGGNDEREQTLNQLLTEMDGF-EGNSGIIVIAATNRPDVLDL 364 Query: 239 AML--SRLPIRIYVPLPDVNSAVEIFKIHLRG--IHYDVPLSRLAKEAVKRLYSGREIAN 294 A+L R ++ V PDV I IH + +H +V L+ +A+ ++G ++AN Sbjct: 365 ALLRPGRFDRQVTVDYPDVQGRELILAIHAQNKKLHEEVQLAAIARRTPG--FTGADLAN 422 Query: 295 VVKLATM 301 V+ A + Sbjct: 423 VLNEAAI 429 >sp|Q55700|FTH1_SYNY3 CELL DIVISION PROTEIN FTSH HOMOLOG 1 >gi|7446577|pir||S76378 cell division protein ftsH-1 - Synechocystis sp. (strain PCC 6803) >gi|1001602|dbj|BAA10230.1| (D64000) cell division protein FtsH [Synechocystis sp.] Length = 627 Score = 116 bits (289), Expect = 3e-25 Identities = 76/247 (30%), Positives = 134/247 (53%), Gaps = 23/247 (9%) Query: 73 GKNEYFDKLKALIK---RSTITWNDIGGLREAKKLIAQAIGLSIAKSP-------IEPPQ 122 G+ F K KA + ++ + ++D+ G+ EAK+ + + + + K P + P+ Sbjct: 149 GQAMNFGKSKARFQMDAKTGVMFDDVAGIDEAKEELQEVV--TFLKQPERFTAVGAKIPK 206 Query: 123 GILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPS 182 G+LL GPPGTGK+LLA A+A FFS+ S+ + + G + + LF A++ +P Sbjct: 207 GVLLVGPPGTGKTLLAKAIAGEAGVPFFSISGSEFVEMFVGVGASRVRDLFKKAKENAPC 266 Query: 183 VIFIDEVDSLTMKRVS----LDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDE 238 +IFIDE+D++ +R + +D + + LL EMDGF E +I++ ATN P LD Sbjct: 267 LIFIDEIDAVGRQRGAGIGGGNDEREQTLNQLLTEMDGF-EGNTGIIIIAATNRPDVLDS 325 Query: 239 AML--SRLPIRIYVPLPDVNSAVEIFKIHLRG--IHYDVPLSRLAKEAVKRLYSGREIAN 294 A++ R ++ V PD + EI ++H R + +V + +A+ +SG ++AN Sbjct: 326 ALMRPGRFDRQVMVDAPDYSGRKEILEVHARNKKLAPEVSIDSIARRTPG--FSGADLAN 383 Query: 295 VVKLATM 301 ++ A + Sbjct: 384 LLNEAAI 390 >pir||T00863 hypothetical protein F17K2.3 - Arabidopsis thaliana >gi|2979543|gb|AAC06152.1| (AC003680) hypothetical protein [Arabidopsis thaliana] Length = 481 Score = 116 bits (289), Expect = 3e-25 Identities = 93/313 (29%), Positives = 149/313 (46%), Gaps = 53/313 (16%) Query: 2 YRLQLLQVQKCQEEFERALSLGHYDKARLIAL-------RCAELLRKIASENLSLSHILL 54 YR ++ Q E +AL +G + R +A A RK S+ ++ + Sbjct: 112 YREKISNWQNQVSERLQALGVGMSENKRTVAYPSSASVSSTASRYRKTLSQKTPVARGGV 171 Query: 55 EEAKKWEEKAKNVRKRREGKNEYFDKLKALIKRS------TITWNDIGGLREAKKLIAQA 108 + ++ A + + +E N Y DKL +I + ++ W+D+ GL AK+ + + Sbjct: 172 ATPRNPKDAAASPKPVKESGNVYDDKLVEMINTTIVDRSPSVKWDDVAGLNGAKQALLEM 231 Query: 109 IGLSIAKSPI-----EPPQ-----GILLFGPPGTGKSLLASAVANSLNATFFSVKASDLL 158 + L + + P + G+LLFGPPG GK++LA AVA+ ATFF+V AS L Sbjct: 232 VILPAKRRDLFTGLRRPARVTSLLGLLLFGPPGNGKTMLAKAVASESQATFFNVSASSLT 291 Query: 159 SKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDAARRMIGTLLAEMDGFK 218 SK+ ID + ++ + S ++A+RR+ L + DG Sbjct: 292 SKW------------------------IDSI--MSTRSTSENEASRRLKSEFLIQFDGVT 325 Query: 219 ERKDK-VIVLTATNAPWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHY---DVP 274 D VI++ ATN P +LD+A+L RL RIYVPLPD N +FK L+ + D Sbjct: 326 SNPDDLVIIIGATNKPQELDDAVLRRLVKRIYVPLPDSNVRKLLFKTKLKCQPHSLSDGD 385 Query: 275 LSRLAKEAVKRLY 287 + ++ KE +LY Sbjct: 386 IDKIVKETEGKLY 398 >pir||D75448 cell division protein FtsH - Deinococcus radiodurans (strain R1) >gi|6458747|gb|AAF10593.1|AE001953_7 (AE001953) cell division protein FtsH [Deinococcus radiodurans] Length = 655 Score = 116 bits (289), Expect = 3e-25 Identities = 78/223 (34%), Positives = 114/223 (50%), Gaps = 15/223 (6%) Query: 65 KNVRKRREGKNEYFDKLKALI---KRSTITWNDIGGLREAKKLIAQAIGLSIAKSPIEP- 120 +++R G F K KA I + +T+ D+ G EAK+ + + + Sbjct: 169 RSLRGNGGGGASSFAKSKAAIISEGQIKLTFADVAGCDEAKQDLQEVVDFLRQPEKYHQL 228 Query: 121 ----PQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLA 176 P G+LL GPPG+GK+LLA AVA +FS+ SD + + G + + LF A Sbjct: 229 GARIPHGVLLVGPPGSGKTLLAKAVAGEAKVPYFSISGSDFVEMFVGVGAARVRDLFEQA 288 Query: 177 RQLSPSVIFIDEVDSLTMKR----VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNA 232 R+ SP ++FIDE+D++ KR +D + + LL EMDGF +D VI+L ATN Sbjct: 289 RKSSPCIVFIDEIDAVGRKRGMNIQGGNDEREQTLNQLLVEMDGFGSGQD-VIILAATNR 347 Query: 233 PWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDV 273 P LD A+L R ++ V PDV +I +IH R DV Sbjct: 348 PDVLDAALLRPGRFDRQVVVDAPDVRGREQILRIHSRKKPLDV 390 >sp|P54816|TBP7_CAEEL TAT-BINDING HOMOLOG 7 >gi|7498868|pir||T20739 hypothetical protein F11A10.1 - Caenorhabditis elegans >gi|4008355|emb|CAA92596.1| (Z68297) Similarity to Yeast TAT-binding homolog 7 (SW:TBP7_YEAST), contains similarity to Pfam domain: PF00004 (ATPases associated with various cellular activities (AAA)), Score=294.7, E-value=3.7e-85, N=1; PF00439 (Bromodomain), Score=99.1, E-value=7> >gi|4008373|emb|CAA92684.1| (Z68316) Similarity to Yeast TAT-binding homolog 7 (SW:TBP7_YEAST), contains similarity to Pfam domain: PF00004 (ATPases associated with various cellular activities (AAA)), Score=294.7, E-value=3.7e-85, N=1; PF00439 (Bromodomain), Score=99.1, E-value=7> Length = 1242 Score = 116 bits (287), Expect = 5e-25 Identities = 97/343 (28%), Positives = 159/343 (46%), Gaps = 35/343 (10%) Query: 23 GHYDKARLIALRCAELLRKIASENLSLSHILLEEAKKWEEKAKNVRKRREGKNEYFDKLK 82 G ++ R + + E E S HIL++ R R+ + + Sbjct: 339 GERERGRFMPINMTE------KELQSAQHILMD------------RMRKTDAGQGASDID 380 Query: 83 ALIKRSTITWNDIGGLREAKKLIAQAIGLSIA------KSPIEPPQGILLFGPPGTGKSL 136 + S++ ++ +GGL + + + + + K I PP+G++ +GPPGTGK+L Sbjct: 381 PMSVDSSVGFDQVGGLGHHIQSLKEVVLFPMLYPEVFEKFRINPPKGVVFYGPPGTGKTL 440 Query: 137 LASAVANSLN-----ATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDS 191 +A A+AN FF K +D LSK+ GES + + LF A + PS+IF DE+D Sbjct: 441 VARALANECRRGANKVAFFMRKGADCLSKWVGESERQLRLLFDQAYAMRPSIIFFDEIDG 500 Query: 192 LTMKRVSLDDAAR-RMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRI 248 L R S D ++ TLLA MDG + + +V+V+ ATN LD A+ R + Sbjct: 501 LAPVRSSKQDQIHASIVSTLLALMDGL-DGRGEVVVIGATNRLDTLDPALRRPGRFDREL 559 Query: 249 YVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMN 308 LPD+N+ +I IH + P+ +A+ SG A++ L T +L + Sbjct: 560 RFSLPDLNARRQILDIHTSKWEENKPIPE-TLDAIAERTSGYCGADLKFLCTEAVLIGLR 618 Query: 309 PELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDV 351 S D+ T +T + F +AM RI +P ++ D+ Sbjct: 619 SRYPHIYMCSERLKLDVATIKITSEHFGHAMRRI-TPASRRDL 660 >gb|AAF58736.1| (AE003828) CG11919 gene product [Drosophila melanogaster] Length = 897 Score = 116 bits (287), Expect = 5e-25 Identities = 99/354 (27%), Positives = 167/354 (46%), Gaps = 39/354 (11%) Query: 25 YDKARLIALRCAELLRKIASENLSLSHILLEEAKKWEEKAKNVRKRREGKNEYFDKLKAL 84 YD A + +R ++ L +SH AKN+ + ++ + D L A Sbjct: 568 YDNAVRMKIR-----NRLGRTTLDMSHF-----------AKNLT---DMQSSFADSLGAP 608 Query: 85 IKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPIEPPQ----GILLFGPPGTGKSLLASA 140 K + W+DIGGL + K I +IGL + + GILL+GPPGTGK+L+A A Sbjct: 609 -KVPKVYWSDIGGLAKLKDEIQSSIGLPLKHVHLMGKNLRRSGILLYGPPGTGKTLVAKA 667 Query: 141 VANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD 200 VA N +F SV+ +LL+ Y G+S + + +FS AR +P V+F+DE+DSL R Sbjct: 668 VATECNLSFLSVQGPELLNMYVGQSEQNVREVFSRARSAAPCVLFLDELDSLAPNRGVAG 727 Query: 201 DAA---RRMIGTLLAEMDGFK--ERKDKVIVLTATNAPWDLDEAML--SRLPIRIYV-PL 252 D+ R++ LLAEMDG + + +L ATN P +D A+L R YV P Sbjct: 728 DSGGVMDRVVSQLLAEMDGMSDGDTSKPIFILAATNRPDLIDPALLRPGRFDKLFYVGPC 787 Query: 253 PDVNSAVEIFKIHLRGIHYD--VPLSRLAKEAVKRLYSGREIANVVKLATMKMLEE-MNP 309 + + + D V + ++A E +K SG ++ ++ A + + ++ Sbjct: 788 STAEDKAAVLRAQTQRFALDAGVDMEQIA-ERLKSEMSGADLYSICSNAWLSAVRRTIDG 846 Query: 310 ELSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKKYERWAKEFAI 363 LS + L ++ + +DF + + I+ D++ + +++ Sbjct: 847 HLSGTISEKELVPENVIVQE---EDFTKSFNKFVPSISAKDLEYFNNLKASYSV 897 >sp|P94304|FTSH_BACFI CELL DIVISION PROTEIN FTSH HOMOLOG >gi|1813473|gb|AAB41679.1| (U61844) cell division protein [Bacillus firmus] Length = 679 Score = 115 bits (286), Expect = 6e-25 Identities = 87/268 (32%), Positives = 132/268 (48%), Gaps = 28/268 (10%) Query: 49 LSHILLEEAKKWEEKAKNVRKRREGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQA 108 L LL +A+ + N K + K DK KA K D+ G E K+ + + Sbjct: 130 LFFFLLSQAQGGGSRVMNFGKSK-AKMVNEDKKKAKFK-------DVAGADEEKQELVEV 181 Query: 109 IGLSIAKSP-------IEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKY 161 + K P P+G+LL GPPGTGK+LLA AVA FFS+ SD + + Sbjct: 182 V--EFLKDPRKFSAIGARIPKGVLLVGPPGTGKTLLARAVAGEAGVPFFSISGSDFVEMF 239 Query: 162 FGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVS----LDDAARRMIGTLLAEMDGF 217 G + + LF A++ +P +IFIDE+D++ +R + D + + LL EMDGF Sbjct: 240 VGVGASRVRDLFENAKKNAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF 299 Query: 218 KERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRG--IHYDV 273 + +I++ ATN LD A+L R +I V PDVN E+ K+H R ++ DV Sbjct: 300 -SANEGIIIIAATNRADILDPALLRPGRFDRQIQVNRPDVNGREEVLKVHARNKPLNDDV 358 Query: 274 PLSRLAKEAVKRLYSGREIANVVKLATM 301 L +A +SG ++ N++ A + Sbjct: 359 NLKTIATRTPG--FSGADLENLLNEAAL 384 >sp|P36966|PEX6_YARLI PEROXISOME BIOSYNTHESIS PROTEIN PAY4 (PEROXIN-6) >gi|1078611|pir||A53121 peroxisome assembly protein PAY4 - yeast (Yarrowia lipolytica) >gi|393291|gb|AAA16622.1| (L23858) ATPase [Yarrowia lipolytica] Length = 1025 Score = 115 bits (284), Expect = 1e-24 Identities = 81/243 (33%), Positives = 123/243 (50%), Gaps = 25/243 (10%) Query: 33 LRCAELLRKIASEN--------LSLSHILLEEAKKWEEKAKNVRKRREGKNEYFDKLKAL 84 LR + L K+ E L+LSH L+ + A + + +Y D + A Sbjct: 658 LRAIDRLNKLTKERPIATLDDLLTLSHGTLQLTPSDFDDAI-----ADARQKYSDSIGAP 712 Query: 85 IKRSTITWNDIGGLREAKKLIAQAIGLSIA-----KSPIEPPQGILLFGPPGTGKSLLAS 139 + + W+D+GG+ KK I I + ++ GIL +GPPGTGK+LLA Sbjct: 713 -RIPNVGWDDVGGMEGVKKDILDTIETPLKYPHWFSDGVKKRSGILFYGPPGTGKTLLAK 771 Query: 140 AVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL 199 A+A + + FFSVK +LL+ Y GES + +F AR P V+F DE+DS+ +R + Sbjct: 772 AIATTFSLNFFSVKGPELLNMYIGESEANVRRVFQKARDAKPCVVFFDELDSVAPQRRNQ 831 Query: 200 DDAA---RRMIGTLLAEMDGFKER-KDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLP 253 D+ R++ LLAE+DG + V V+ ATN P LDEA+L R +Y+ + Sbjct: 832 GDSGGVMDRIVSQLLAELDGMSTAGGEGVFVVGATNRPDLLDEALLRPGRFDKMLYLGIS 891 Query: 254 DVN 256 D + Sbjct: 892 DTH 894 >dbj|BAB00559.1| (AP001299) contains similarity to 26S proteasome subunit 4~gene_id:F4B12.4 [Arabidopsis thaliana] Length = 1964 Score = 114 bits (283), Expect = 1e-24 Identities = 83/281 (29%), Positives = 135/281 (47%), Gaps = 29/281 (10%) Query: 54 LEEAKKWEEKAKNVRK--RREGKNEYFDKLKALIK----------RSTITWNDIGGLREA 101 +E +KW EK + +RE K + D L+ + ++ W+ + GL Sbjct: 678 VEAEEKWFEKCGEDEEFLKRESKRLHRDLLRVAPEYIGGSDSESGKAFEGWDSVAGLEGV 737 Query: 102 KKLIAQAIGLSIAKSP------IEPPQGILLFGPPGTGKSLLASAVANSL-----NATFF 150 + + + + + + + PP+GILL G PGTGK+L+ A+ SL +F Sbjct: 738 TQCMKEVVLIPLLYPEFFDNLGLTPPRGILLHGHPGTGKTLVVRALIGSLARGNRRIAYF 797 Query: 151 SVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDAAR-RMIGT 209 + K +D L KY G++ + + LF +A + PS+IF DE+D L KR D ++ T Sbjct: 798 ARKGADCLGKYVGDAERQLRLLFQVAEKCQPSIIFFDEIDGLAPKRSRQQDQTHSSVVST 857 Query: 210 LLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLR 267 LLA +DG K R V+V+ ATN P +D A+ R IY PLP V+ I +H R Sbjct: 858 LLALLDGLKSR-GSVVVIGATNYPDAIDPALRRPGRFDREIYFPLPSVDDRAAIISLHTR 916 Query: 268 GIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMN 308 + P+S + + + +G A++ L T + +N Sbjct: 917 --KWPKPVSGYLLKWIAKETAGFAGADIQALCTQAAMIALN 955 >sp|P42811|PRS2_METTM PUTATIVE 26S PROTEASE REGULATORY SUBUNIT HOMOLOG MTH1011 >gi|1076133|pir||S51137 ATP-dependent 26S proteinase regulatory subunit 8 homolog - Methanobacterium thermoautotrophicum (strain Marburg) >gi|809719|emb|CAA58665.1| (X83691) gtg start point [Methanobacterium thermoautotrophicum] Length = 372 Score = 112 bits (277), Expect = 7e-24 Identities = 84/265 (31%), Positives = 135/265 (50%), Gaps = 15/265 (5%) Query: 72 EGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGLSIAKSPIE----PPQGILLF 127 E + E F ++K S IT +D+ G +AK I I + + P P+ +L Sbjct: 111 ENEREEFHEVK-----SDITMDDVIGQEDAK--IKCRIIMRYLEDPDRFRDWAPRNVLFH 163 Query: 128 GPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFID 187 G PGTGK++LA ++AN L + +KA+ L+ ++ G+ ++ I L+ LA + +PSVIFID Sbjct: 164 GSPGTGKTMLAKSLANELRVPLYLIKATSLIGEHVGDGARQIHELYELASKTAPSVIFID 223 Query: 188 EVDSLTMKR--VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAMLSRLP 245 E+D++ + R SL ++ LL EMDG + V+ + ATN P LD A+ SR Sbjct: 224 EMDAIGLDRRFQSLRGDVSEVVNALLTEMDGINQNWG-VVTIGATNNPELLDNAIRSRFE 282 Query: 246 IRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREI-ANVVKLATMKML 304 I LP + + + ++ + DV S + + SGR+I V+K A + L Sbjct: 283 EEIEFKLPGDDERRMMLEKYIETMPLDVDFSVDKLVKLTKGMSGRDIKERVLKTALHRAL 342 Query: 305 EEMNPELSDPLRVSTLKGRDLTTRP 329 + +P + LK RDL + P Sbjct: 343 ADESPRVEREHIEYALKERDLKSEP 367 >pir||D70198 cell division protein (ftsH) homolog - Lyme disease spirochete >gi|2688712|gb|AAC67120.1| (AE001177) cell division protein (ftsH) [Borrelia burgdorferi] Length = 639 Score = 111 bits (274), Expect = 2e-23 Identities = 80/244 (32%), Positives = 120/244 (48%), Gaps = 29/244 (11%) Query: 66 NVRKRREGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQAIGL-----SIAKSPIEP 120 N +K GKN+ IT+ D+ G E K+ + + + K + Sbjct: 158 NAQKYEAGKNK-------------ITFKDVAGQEEVKQELREVVEFLKNPKKFEKIGAKI 204 Query: 121 PQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLS 180 P+G+LL G PGTGK+LLA AVA +FF + SD + + G + + LF AR+ S Sbjct: 205 PKGVLLVGSPGTGKTLLAKAVAGEAGVSFFHMSGSDFVEMFVGVGASRVRDLFDNARKNS 264 Query: 181 PSVIFIDEVDSLTMKRVS----LDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDL 236 P +IFIDE+D++ R + D + + LL EMDGF + VIV+ ATN P L Sbjct: 265 PCIIFIDELDAVGRSRGAGLGGGHDEREQTLNQLLVEMDGFGTHTN-VIVMAATNRPDVL 323 Query: 237 DEAML--SRLPIRIYVPLPDVNSAVEIFKIH--LRGIHYDVPLSRLAKEAVKRLYSGREI 292 D A+L R ++ V LPD+ I IH + D+ L +A+ SG ++ Sbjct: 324 DSALLRPGRFDRQVTVSLPDIKEREAILNIHSLKTKLSKDINLQVIARATPGA--SGADL 381 Query: 293 ANVV 296 AN++ Sbjct: 382 ANLI 385 >emb|CAB51031.1| (AJ243811) l(3)70Da [Drosophila melanogaster] Length = 1006 Score = 111 bits (274), Expect = 2e-23 Identities = 87/258 (33%), Positives = 124/258 (47%), Gaps = 30/258 (11%) Query: 116 SPIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSL 175 SP+ G+LL+GPPGTGK+ L S +A S N SVK +LL+KY G+S + + LF+ Sbjct: 749 SPLRNQAGVLLYGPPGTGKTYLVSQLATSWNLRIISVKGPELLAKYIGQSEENVRNLFNR 808 Query: 176 ARQLSPSVIFIDEVDSLTMKR-VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPW 234 AR P V+F DE DSL KR R++ LL E+DG E V V+ AT+ P Sbjct: 809 ARSARPCVLFFDEFDSLAPKRGHDSTGVTDRVVNQLLTELDGV-EGLQGVTVIAATSRPE 867 Query: 235 DLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHYD--VPLSRLAKEAVKRLYSGR 290 LD A+L R+ + PLPD + V IF+ + D V A + Y+G Sbjct: 868 LLDPALLRSGRIDRLVECPLPDAPARVRIFEALSSTLSLDECVDFDWFAGKTAN--YTGA 925 Query: 291 EIANVVKLATMKMLEEMNPELSDP--LRVSTLKGRDL-----TTRPLTLDDFKYAMARIK 343 +I +++ A M ++E + + +LK + L TTRP Sbjct: 926 DIQSILTSANMAAVKEALAQFGHEKLAKKISLKQKHLIESFQTTRP-------------- 971 Query: 344 SPITKSDVKKYERWAKEF 361 ++ SDV KY R F Sbjct: 972 -SLSASDVAKYHRTYARF 988 >gb|AAF49760.1| (AE003536) l(3)70Da gene product [Drosophila melanogaster] Length = 1006 Score = 111 bits (274), Expect = 2e-23 Identities = 87/258 (33%), Positives = 124/258 (47%), Gaps = 30/258 (11%) Query: 116 SPIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSL 175 SP+ G+LL+GPPGTGK+ L S +A S N SVK +LL+KY G+S + + LF+ Sbjct: 749 SPLRNQAGVLLYGPPGTGKTYLVSQLATSWNLRIISVKGPELLAKYIGQSEENVRNLFNR 808 Query: 176 ARQLSPSVIFIDEVDSLTMKR-VSLDDAARRMIGTLLAEMDGFKERKDKVIVLTATNAPW 234 AR P V+F DE DSL KR R++ LL E+DG E V V+ AT+ P Sbjct: 809 ARSARPCVLFFDEFDSLAPKRGHDSTGVTDRVVNQLLTELDGV-EGLQGVTVIAATSRPE 867 Query: 235 DLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHYD--VPLSRLAKEAVKRLYSGR 290 LD A+L R+ + PLPD + V IF+ + D V A + Y+G Sbjct: 868 LLDPALLRSGRIDRLVECPLPDAPARVRIFEALSSTLSLDECVDFDWFAGKTAN--YTGA 925 Query: 291 EIANVVKLATMKMLEEMNPELSDP--LRVSTLKGRDL-----TTRPLTLDDFKYAMARIK 343 +I +++ A M ++E + + +LK + L TTRP Sbjct: 926 DIQSILTSANMAAVKEALAQFGHEKLAKKISLKQKHLIESFQTTRP-------------- 971 Query: 344 SPITKSDVKKYERWAKEF 361 ++ SDV KY R F Sbjct: 972 -SLSASDVAKYHRTYARF 988 >dbj|BAB03804.1| (AP001507) cell-division protein (ATP-dependent Zn metallopeptidase) [Bacillus halodurans] Length = 657 Score = 110 bits (272), Expect = 3e-23 Identities = 86/279 (30%), Positives = 134/279 (47%), Gaps = 28/279 (10%) Query: 49 LSHILLEEAKKWEEKAKNVRKRREGKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQA 108 L LL +A+ + N K + K DK KA K D+ G E K+ + + Sbjct: 123 LFFFLLSQAQGGGSRVMNFGKSK-AKMVNEDKKKAKFK-------DVAGADEEKQELVEV 174 Query: 109 IGLSIAKSP-------IEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKY 161 + K P P+G+LL GPPGTGK+LLA AVA FFS+ SD + + Sbjct: 175 V--EFLKDPRKFSAIGARIPKGVLLVGPPGTGKTLLARAVAGEAGVPFFSISGSDFVEMF 232 Query: 162 FGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVS----LDDAARRMIGTLLAEMDGF 217 G + + LF A++ +P +IFIDE+D++ +R + D + + LL EMDGF Sbjct: 233 VGVGASRVRDLFENAKKNAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF 292 Query: 218 KERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHL--RGIHYDV 273 + +I++ ATN LD A+L R +I V PDV E+ K+H + + DV Sbjct: 293 -SANEGIIIIAATNRADILDPALLRPGRFDRQITVGRPDVKGREEVLKVHASNKPLADDV 351 Query: 274 PLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPELS 312 L +A +SG ++ N++ A + + ++S Sbjct: 352 NLKTIATRTPG--FSGADLENLLNEAALVAARQDEKKIS 388 >gi|11498088 AAA superfamily ATPase [Archaeoglobus fulgidus] >gi|7482915|pir||E69309 ATPase AAA homolog - Archaeoglobus fulgidus >gi|2650149|gb|AAB90760.1| (AE001071) AAA superfamily ATPase [Archaeoglobus fulgidus] Length = 409 Score = 105 bits (259), Expect = 9e-22 Identities = 97/320 (30%), Positives = 151/320 (46%), Gaps = 25/320 (7%) Query: 16 FERALSLGHYDKA-RLIALRCAELLRKIAS-----ENLSLSHILLEEAKKW-------EE 62 F R L +D A + A R EL++K + +N + EEAKK +E Sbjct: 71 FSRQYILTSFDLAVKWFASRGVELIKKNPALAYFYQNYDSLDVSYEEAKKANLPKHGDKE 130 Query: 63 KAKNVRKRREGKNEYFDKLKALIKRST----ITWNDIG----GLREAKKL-IAQAIGLSI 113 K + + E K+E + L + S + + ++ L E +K+ IA + Sbjct: 131 WLKGLIEELEKKDETREMLSLVRVLSPEEIPVDFREVALSEEQLEEVRKIEIALEERSFL 190 Query: 114 AKSPIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALF 173 K + +L GPPGTGK+ A A++ L VK S + S+Y GE+SK I +F Sbjct: 191 RKIGLSDIGKLLFIGPPGTGKTTTARALSKKLYLPLLEVKLSMITSQYLGETSKNIEKIF 250 Query: 174 SLARQLSPSVIFIDEVDSLTMKRVSLDDAA-RRMIGTLLAEMDGFKERKDKVIVLTATNA 232 +AR +SP ++FIDE D + R S + AA +R + TLL +D +D V+++ ATN Sbjct: 251 DIARMMSPCILFIDEFDYVAKMRTSDEHAAIKRAVNTLLKSIDDINLVEDGVLLIAATNH 310 Query: 233 PWDLDEAMLSRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREI 292 P LD A+ R I P P IF+I L I + + L +E ++G +I Sbjct: 311 PSLLDPAVWRRFDKVIEFPEPAEAIRKRIFEIFLARIDGNFNIDELVRETDG--FTGADI 368 Query: 293 ANVVKLATMKMLEEMNPELS 312 VV+ A + L + EL+ Sbjct: 369 KLVVREAVLDALLQGRRELT 388 >dbj|BAA85441.1| (AP000616) EST D15969(C1695) corresponds to a region of the predicted gene.; similar to valosin-containing protein (U20213) [Oryza sativa] Length = 781 Score = 104 bits (258), Expect = 1e-21 Identities = 92/279 (32%), Positives = 129/279 (45%), Gaps = 54/279 (19%) Query: 45 ENLSLSHILLEEAKKWEEKAKNVRKRREGKNEYFDKLKALIKRSTITWNDIGGLREAKKL 104 E LS++ EEA K + + RREG + D +TW+D+GGL +K Sbjct: 461 EGLSITMDDFEEATKMVQPSL----RREGFSSIPD----------VTWDDVGGLDSLRKE 506 Query: 105 IAQAIGLSIAKSPIE-------PPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDL 157 + I + K P E G LLFGPPG GK+L+A AVA+ A F +K +L Sbjct: 507 FDRYI-IRCIKQPEEYKTFGLNMQAGFLLFGPPGCGKTLIAKAVAHEAGANFIHIKGPEL 565 Query: 158 LSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLDDAARRMIGTLLAEMDGF 217 L+KY GES + +F A+ +P ++F DE LL E+DG Sbjct: 566 LNKYVGESESEVRKIFIRAQTNTPCILFFDE---------------------LLIELDGA 604 Query: 218 KERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRG--IHYDV 273 ERK V V+ ATN +D+A L R + YVPLP + V I + R I V Sbjct: 605 GERKG-VFVIGATNRIDVIDDAALRPGRFGKKHYVPLPGADERVSILRALARNKPISSSV 663 Query: 274 PLSRLAKEAVKRLYSGREIANV------VKLATMKMLEE 306 L LA+ + +G ++A++ V A M LEE Sbjct: 664 DLGALARREECKNLTGADLASMEPMGHFVNEAAMAALEE 702 Score = 92.8 bits (227), Expect = 5e-18 Identities = 63/234 (26%), Positives = 115/234 (48%), Gaps = 25/234 (10%) Query: 91 TWNDIGGLREAKKLIAQAIGLSIAKSPI------EPPQGILLFGPPGTGKSLLASAVANS 144 T++D+GG+ + + + + + + +P G+LL GPPG GK+ LA A+AN Sbjct: 189 TFSDLGGMESVIEQLMMEVVVPLCHPEVPRWLGVKPVAGLLLHGPPGCGKTTLAHAIANE 248 Query: 145 LNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSLD-DAA 203 F+ + A +++S G S + I +LF A + +PS++FIDE+D++ KR +L + Sbjct: 249 TGVPFYKISAPEVVSGVSGASEENIRSLFKKAYRTAPSIVFIDEIDAIASKRENLQREME 308 Query: 204 RRMIGTLLAEMDGF----------------KERKDKVIVLTATNAPWDLDEAML--SRLP 245 RR++ L+ MD + +++ VIV+ ATN P +D+A+ R Sbjct: 309 RRIVTQLMTCMDEYHQQIGSGSGDVGSESAEKKPGYVIVIGATNRPDAVDQALRRPGRFD 368 Query: 246 IRIYVPLPDVNSAVEIFKIHLRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLA 299 I + +PD + +I + R + + L L + G ++ +V A Sbjct: 369 REISLGVPDEYARKKILMMLTRNLRLEGQLDLLKIARATSSFVGADLKALVDKA 422 >sp|P46509|YL15_MYCLE PUTATIVE AAA-FAMILY ATPASE MLCB2533.12/A2126A >gi|2145850|pir||S72845 H+-transporting ATP synthase (EC 3.6.1.34) - Mycobacterium leprae >gi|467000|gb|AAA17185.1| (U00017) a2126a; B2126_C1_167 [Mycobacterium leprae] >gi|4200269|emb|CAA22926.1| (AL035310) putative ATPase MLCB2533.12 [Mycobacterium leprae] Length = 609 Score = 104 bits (257), Expect = 2e-21 Identities = 86/293 (29%), Positives = 141/293 (47%), Gaps = 56/293 (19%) Query: 18 RALSLGHYDKARLIALRCAELLRKIASENLSLSHILLEEAKKWEEKAKNVRKRREGKNEY 77 RAL +GH D+ R++ L + +ENL L+ RK R G + Sbjct: 173 RALVVGHADEERIVCLA-----EPLVAENL------LDGVPGALNDDSRPRKLRPGDSLL 221 Query: 78 FD-------------KLKALIKRST--ITWNDIGGLREAKKLIAQAIGLSIAKSPI---- 118 D +++ L+ +++ DIGGL + I A+ L + Sbjct: 222 VDPKAGYAFERVPKAEVEDLVLEEVPDVSYQDIGGLTRQIEQIRDAVELPFLHKELYREY 281 Query: 119 --EPPQGILLFGPPGTGKSLLASAVANSL---------------NATFFSVKASDLLSKY 161 PP+G+LL+GPPG GK+L+A AVANSL + F ++K +LL+K+ Sbjct: 282 ALRPPKGVLLYGPPGCGKTLIAKAVANSLAKKMAEVRGDDAREAKSYFLNIKGPELLNKF 341 Query: 162 FGESSKLISALFSLARQL----SPSVIFIDEVDSLTMKRVS--LDDAARRMIGTLLAEMD 215 GE+ + I +F AR+ +P ++F DE+DS+ R + D ++ LL+E+D Sbjct: 342 VGETERHIRLIFQRAREKASEGTPVIVFFDEMDSIFRTRGTGVSSDVETTVVPQLLSEID 401 Query: 216 GFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHL 266 G E + VIV+ A+N +D A+L RL ++I + PD +A +I+ +L Sbjct: 402 GV-EGLENVIVIGASNREDMIDPAILRPGRLDVKIKIERPDAEAAQDIYSKYL 453 >gi|4507173 paraplegin [Homo sapiens] >gi|3273089|emb|CAA76314.1| (Y16610) paraplegin [Homo sapiens] Length = 795 Score = 102 bits (251), Expect = 8e-21 Identities = 92/335 (27%), Positives = 153/335 (45%), Gaps = 39/335 (11%) Query: 1 MYRLQLLQVQKCQEEFERA---LSLGHYDKARLIALRCAELLRKIASENLSLSHILLEEA 57 MYR+Q+ + K +E+ A L++ D+ + R + S ++ + + Sbjct: 211 MYRMQVANIDKFEEKLRAAEDELNIEAKDRIPVSYKRTGFFGNALYSVGMTAVGLAI--- 267 Query: 58 KKWEEKAKNVRKRREGKNEYFDKLKALIKRSTI---------TWNDIGGLREAKKLIAQA 108 W REG F++LK + R TI ++ D+ G+ EAK + + Sbjct: 268 -LWYVFRLAGMTGREGGFSAFNQLK--MARFTIVDGKMGKGVSFKDVAGMHEAKLEVREF 324 Query: 109 IGLSIAKSP-------IEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKY 161 + KSP + P+G LL GPPG GK+LLA AVA F ++ + + Sbjct: 325 V--DYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVI 382 Query: 162 FGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL-----DDAARRMIGTLLAEMDG 216 G + + +LF AR +P +++IDE+D++ KR + + + + LL EMDG Sbjct: 383 GGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGFSNTEEEQTLNQLLVEMDG 442 Query: 217 FKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVP 274 D VIVL +TN LD A++ RL +++ LP + EIF+ HL+ + Sbjct: 443 M-GTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQERREIFEQHLKSLKL-TQ 500 Query: 275 LSRLAKEAVKRL---YSGREIANVVKLATMKMLEE 306 S + + L +SG +IAN+ A + E Sbjct: 501 SSTFYSQRLAELTPGFSGADIANICNEAALHAARE 535 >gb|AAD28099.1| (AF080525) paraplegin [Homo sapiens] Length = 795 Score = 102 bits (251), Expect = 8e-21 Identities = 92/335 (27%), Positives = 153/335 (45%), Gaps = 39/335 (11%) Query: 1 MYRLQLLQVQKCQEEFERA---LSLGHYDKARLIALRCAELLRKIASENLSLSHILLEEA 57 MYR+Q+ + K +E+ A L++ D+ + R + S ++ + + Sbjct: 211 MYRMQVANIDKFEEKLRAAEDELNIEAKDRIPVSYKRTGFFGNALYSVGMTAVGLAI--- 267 Query: 58 KKWEEKAKNVRKRREGKNEYFDKLKALIKRSTI---------TWNDIGGLREAKKLIAQA 108 W REG F++LK + R TI ++ D+ G+ EAK + + Sbjct: 268 -LWYVFRLAGMTGREGGFSAFNQLK--MARFTIVDGKMGKGVSFKDVAGMHEAKLEVREF 324 Query: 109 IGLSIAKSP-------IEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDLLSKY 161 + KSP + P+G LL GPPG GK+LLA AVA F ++ + + Sbjct: 325 V--DYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVI 382 Query: 162 FGESSKLISALFSLARQLSPSVIFIDEVDSLTMKRVSL-----DDAARRMIGTLLAEMDG 216 G + + +LF AR +P +++IDE+D++ KR + + + + LL EMDG Sbjct: 383 GGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGFSNTEEEQTLNQLLVEMDG 442 Query: 217 FKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLRGIHYDVP 274 D VIVL +TN LD A++ RL +++ LP + EIF+ HL+ + Sbjct: 443 M-GTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQERREIFEQHLKSLKL-TQ 500 Query: 275 LSRLAKEAVKRL---YSGREIANVVKLATMKMLEE 306 S + + L +SG +IAN+ A + E Sbjct: 501 SSTFYSQRLAELTPGFSGADIANICNEAALHAARE 535 >pir||G01234 N-ethylmaleimide-sensitive factor - human (fragment) >gi|467977|gb|AAA17411.1| (U03985) N-ethylmaleimide-sensitive factor [Homo sapiens] Length = 751 Score = 92.8 bits (227), Expect = 5e-18 Identities = 84/269 (31%), Positives = 137/269 (50%), Gaps = 37/269 (13%) Query: 62 EKAKNVRKRREGKNEYFDKLKALIKRSTITWN----DIGGL-REAKKLIAQAIGLSIAKS 116 EKA+N GK + + +++I WN IGGL +E + +A + Sbjct: 193 EKAENSSLNLIGKAKTKENRQSIINPD---WNFEKMGIGGLDKEFSDIFRRAFAFRVFPP 249 Query: 117 PIEPP------QGILLFGPPGTGKSLLASAVANSLNATFFS-VKASDLLSKYFGESSKLI 169 I +GILL+GPPG GK+LLA + LNA V ++L+KY GES I Sbjct: 250 EIVEQMGCIHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANI 309 Query: 170 SALFSLA----RQLSPS----VIFIDEVDSLTMKRVSLDDAA---RRMIGTLLAEMDGFK 218 LF+ A R+L + +I DE+D++ +R S+ + ++ LL+++DG Sbjct: 310 RKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGV- 368 Query: 219 ERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIH---LRG---IH 270 E+ + ++V+ TN P +DEA+L RL +++ + LPD ++I IH +RG + Sbjct: 369 EQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLS 428 Query: 271 YDVPLSRLAKEAVKRLYSGREIANVVKLA 299 DV + LA E + +SG E+ +V+ A Sbjct: 429 ADVDIKELAVET--KNFSGAELEGLVRAA 455 >gi|11079228 N-ethylmaleimide-sensitive factor [Homo sapiens] >gi|1171773|sp|P46459|NSF_HUMAN VESICULAR-FUSION PROTEIN NSF (N-ETHYLMALEIMIDE-SENSITIVE FUSION PROTEIN) (NEM-SENSITIVE FUSION PROTEIN) >gi|7920147|gb|AAF70545.1|AF135168_1 (AF135168) N-ethylmaleimide-sensitive factor [Homo sapiens] Length = 744 Score = 92.8 bits (227), Expect = 5e-18 Identities = 84/269 (31%), Positives = 137/269 (50%), Gaps = 37/269 (13%) Query: 62 EKAKNVRKRREGKNEYFDKLKALIKRSTITWN----DIGGL-REAKKLIAQAIGLSIAKS 116 EKA+N GK + + +++I WN IGGL +E + +A + Sbjct: 186 EKAENSSLNLIGKAKTKENRQSIINPD---WNFEKMGIGGLDKEFSDIFRRAFAFRVFPP 242 Query: 117 PIEPP------QGILLFGPPGTGKSLLASAVANSLNATFFS-VKASDLLSKYFGESSKLI 169 I +GILL+GPPG GK+LLA + LNA V ++L+KY GES I Sbjct: 243 EIVEQMGCIHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANI 302 Query: 170 SALFSLA----RQLSPS----VIFIDEVDSLTMKRVSLDDAA---RRMIGTLLAEMDGFK 218 LF+ A R+L + +I DE+D++ +R S+ + ++ LL+++DG Sbjct: 303 RKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGV- 361 Query: 219 ERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIH---LRG---IH 270 E+ + ++V+ TN P +DEA+L RL +++ + LPD ++I IH +RG + Sbjct: 362 EQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLS 421 Query: 271 YDVPLSRLAKEAVKRLYSGREIANVVKLA 299 DV + LA E + +SG E+ +V+ A Sbjct: 422 ADVDIKELAVET--KNFSGAELEGLVRAA 448 >gb|AAF04745.2|AF102846_1 (AF102846) N-ethylmaleimide-sensitive factor [Homo sapiens] Length = 744 Score = 92.8 bits (227), Expect = 5e-18 Identities = 84/269 (31%), Positives = 137/269 (50%), Gaps = 37/269 (13%) Query: 62 EKAKNVRKRREGKNEYFDKLKALIKRSTITWN----DIGGL-REAKKLIAQAIGLSIAKS 116 EKA+N GK + + +++I WN IGGL +E + +A + Sbjct: 186 EKAENSSLNLIGKAKTKENRQSIINPD---WNFEKMGIGGLDKEFSDIFRRAFAFRVFPP 242 Query: 117 PIEPP------QGILLFGPPGTGKSLLASAVANSLNATFFS-VKASDLLSKYFGESSKLI 169 I +GILL+GPPG GK+LLA + LNA V ++L+KY GES I Sbjct: 243 EIVEQMGCIHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANI 302 Query: 170 SALFSLA----RQLSPS----VIFIDEVDSLTMKRVSLDDAA---RRMIGTLLAEMDGFK 218 LF+ A R+L + +I DE+D++ +R S+ + ++ LL+++DG Sbjct: 303 RKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGV- 361 Query: 219 ERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIH---LRG---IH 270 E+ + ++V+ TN P +DEA+L RL +++ + LPD ++I IH +RG + Sbjct: 362 EQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLS 421 Query: 271 YDVPLSRLAKEAVKRLYSGREIANVVKLA 299 DV + LA E + +SG E+ +V+ A Sbjct: 422 ADVDIKELAVET--KNFSGAELEGLVRAA 448 >pir||S04235 vesicular fusion protein NSF - Chinese hamster (fragment) >gi|49518|emb|CAA33678.1| (X15652) N-ethylmaleimide sensitive fusion protein [Cricetulus longicaudatus] >gi|226383|prf||1509333A NEM sensitive fusion protein [Cricetulus griseus] Length = 752 Score = 92.4 bits (226), Expect = 7e-18 Identities = 84/269 (31%), Positives = 138/269 (51%), Gaps = 37/269 (13%) Query: 62 EKAKNVRKRREGKNEYFDKLKALIKRSTITWN----DIGGL-REAKKLIAQAIGLSIAKS 116 EKA+N GK + + +++I WN IGGL +E + +A + Sbjct: 194 EKAENSSLNLIGKAKTKENRQSIINPD---WNFEKMGIGGLDKEFSDIFRRAFASRVFPP 250 Query: 117 PI------EPPQGILLFGPPGTGKSLLASAVANSLNATFFS-VKASDLLSKYFGESSKLI 169 I + +GILL+GPPG GK+LLA + LNA V ++L+KY GES I Sbjct: 251 EIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANI 310 Query: 170 SALFSLA----RQLSPS----VIFIDEVDSLTMKRVSLDDAA---RRMIGTLLAEMDGFK 218 LF+ A R+L + +I DE+D++ +R S+ + ++ LL+++DG Sbjct: 311 RKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGV- 369 Query: 219 ERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIH---LRG---IH 270 E+ + ++V+ TN P +DEA+L RL +++ + LPD ++I IH +RG + Sbjct: 370 EQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLS 429 Query: 271 YDVPLSRLAKEAVKRLYSGREIANVVKLA 299 DV + LA E + +SG E+ +V+ A Sbjct: 430 ADVDIKELAVET--KNFSGAELEGLVRAA 456 >sp|P18708|NSF_CRIGR VESICULAR-FUSION PROTEIN NSF (N-ETHYLMALEIMIDE-SENSITIVE FUSION PROTEIN) (NEM-SENSITIVE FUSION PROTEIN) Length = 744 Score = 92.4 bits (226), Expect = 7e-18 Identities = 84/269 (31%), Positives = 138/269 (51%), Gaps = 37/269 (13%) Query: 62 EKAKNVRKRREGKNEYFDKLKALIKRSTITWN----DIGGL-REAKKLIAQAIGLSIAKS 116 EKA+N GK + + +++I WN IGGL +E + +A + Sbjct: 186 EKAENSSLNLIGKAKTKENRQSIINPD---WNFEKMGIGGLDKEFSDIFRRAFASRVFPP 242 Query: 117 PI------EPPQGILLFGPPGTGKSLLASAVANSLNATFFS-VKASDLLSKYFGESSKLI 169 I + +GILL+GPPG GK+LLA + LNA V ++L+KY GES I Sbjct: 243 EIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANI 302 Query: 170 SALFSLA----RQLSPS----VIFIDEVDSLTMKRVSLDDAA---RRMIGTLLAEMDGFK 218 LF+ A R+L + +I DE+D++ +R S+ + ++ LL+++DG Sbjct: 303 RKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGV- 361 Query: 219 ERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIH---LRG---IH 270 E+ + ++V+ TN P +DEA+L RL +++ + LPD ++I IH +RG + Sbjct: 362 EQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLS 421 Query: 271 YDVPLSRLAKEAVKRLYSGREIANVVKLA 299 DV + LA E + +SG E+ +V+ A Sbjct: 422 ADVDIKELAVET--KNFSGAELEGLVRAA 448 >gi|6679140 N-ethylmaleimide sensitive fusion protein [Mus musculus] >gi|1171774|sp|P46460|NSF_MOUSE VESICULAR-FUSION PROTEIN NSF (N-ETHYLMALEIMIDE-SENSITIVE FUSION PROTEIN) (NEM-SENSITIVE FUSION PROTEIN) (SKD2 PROTEIN) >gi|557878|gb|AAA50498.1| (U10120) SKD2 [Mus musculus] Length = 744 Score = 92.4 bits (226), Expect = 7e-18 Identities = 84/269 (31%), Positives = 138/269 (51%), Gaps = 37/269 (13%) Query: 62 EKAKNVRKRREGKNEYFDKLKALIKRSTITWN----DIGGL-REAKKLIAQAIGLSIAKS 116 EKA+N GK + + +++I WN IGGL +E + +A + Sbjct: 186 EKAENSSLNLIGKAKTKENRQSIINPD---WNFEKMGIGGLDKEFSDIFRRAFASRVFPP 242 Query: 117 PI------EPPQGILLFGPPGTGKSLLASAVANSLNATFFS-VKASDLLSKYFGESSKLI 169 I + +GILL+GPPG GK+LLA + LNA V ++L+KY GES I Sbjct: 243 EIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANI 302 Query: 170 SALFSLA----RQLSPS----VIFIDEVDSLTMKRVSLDDAA---RRMIGTLLAEMDGFK 218 LF+ A R+L + +I DE+D++ +R S+ + ++ LL+++DG Sbjct: 303 RKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGV- 361 Query: 219 ERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIH---LRG---IH 270 E+ + ++V+ TN P +DEA+L RL +++ + LPD ++I IH +RG + Sbjct: 362 EQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLS 421 Query: 271 YDVPLSRLAKEAVKRLYSGREIANVVKLA 299 DV + LA E + +SG E+ +V+ A Sbjct: 422 ADVDIKELAVET--KNFSGAELEGLVRAA 448 >gb|AAD39485.1|AF142097_1 (AF142097) N-ethylmaleimide sensitive factor [Rattus norvegicus] >gi|6007811|gb|AAF01051.1|AF189019_1 (AF189019) N-ethylmaleimide sensitive factor [Rattus norvegicus] Length = 744 Score = 92.4 bits (226), Expect = 7e-18 Identities = 84/269 (31%), Positives = 138/269 (51%), Gaps = 37/269 (13%) Query: 62 EKAKNVRKRREGKNEYFDKLKALIKRSTITWN----DIGGL-REAKKLIAQAIGLSIAKS 116 EKA+N GK + + +++I WN IGGL +E + +A + Sbjct: 186 EKAENSSLNLIGKAKTKENRQSIINPD---WNFEKMGIGGLDKEFSDIFRRAFASRVFPP 242 Query: 117 PI------EPPQGILLFGPPGTGKSLLASAVANSLNATFFS-VKASDLLSKYFGESSKLI 169 I + +GILL+GPPG GK+LLA + LNA V ++L+KY GES I Sbjct: 243 EIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANI 302 Query: 170 SALFSLA----RQLSPS----VIFIDEVDSLTMKRVSLDDAA---RRMIGTLLAEMDGFK 218 LF+ A R+L + +I DE+D++ +R S+ + ++ LL+++DG Sbjct: 303 RKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGV- 361 Query: 219 ERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIH---LRG---IH 270 E+ + ++V+ TN P +DEA+L RL +++ + LPD ++I IH +RG + Sbjct: 362 EQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLS 421 Query: 271 YDVPLSRLAKEAVKRLYSGREIANVVKLA 299 DV + LA E + +SG E+ +V+ A Sbjct: 422 ADVDIKELAVET--KNFSGAELEGLVRAA 448 >gb|AAC46844.1| (U28836) N-ethylmaleimide sensitive fusion protein-2 [Drosophila melanogaster] Length = 744 Score = 88.9 bits (217), Expect = 8e-17 Identities = 88/303 (29%), Positives = 145/303 (47%), Gaps = 54/303 (17%) Query: 58 KKWEEKAKNVRKRREGKNEYFDKLKALIKRSTIT--WN----DIGGLREAKKLIAQAIGL 111 +K E N++ R +GK ++++S I W+ IGGL + I + Sbjct: 183 EKAENSVLNLQGRSKGK---------IVRQSIINPDWDFGKMGIGGLDKEFNAIFRRAFA 233 Query: 112 SIAKSP-------IEPPQGILLFGPPGTGKSLLASAVANSLNATFFS-VKASDLLSKYFG 163 S P I+ +GILL+GPPGTGK+L+A + LNA V +L KY G Sbjct: 234 SRVFPPELVEQLGIKHVKGILLYGPPGTGKTLMARQIGTMLNAREPKIVNGPQILDKYVG 293 Query: 164 ESSKLISALFSLA----RQLSPS----VIFIDEVDSLTMKRVSL---DDAARRMIGTLLA 212 ES I LF+ A ++L P+ +I DE+D++ R S+ ++ LLA Sbjct: 294 ESEANIRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAICKARGSVAGNSGVHDTVVNQLLA 353 Query: 213 EMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLR--- 267 ++DG E+ + ++V+ TN +DEA+L RL +++ + LP+ V+I IH + Sbjct: 354 KIDGV-EQLNNILVIGMTNRRDMIDEALLRPGRLEVQMEISLPNEQGRVQILNIHTKRMR 412 Query: 268 ---GIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEM---------NPELSDPL 315 I DV + +A A + +SG E+ +V+ A + + +PE + L Sbjct: 413 DFNKIASDVDNNEIA--AKTKNFSGAELEGLVRAAQSTAMNRLIKADSKVHVDPEAMEKL 470 Query: 316 RVS 318 RV+ Sbjct: 471 RVT 473 >sp|P54351|NSF2_DROME VESICULAR-FUSION PROTEIN NSF2 (N-ETHYLMALEIMIDE-SENSITIVE FUSION PROTEIN 2) (NEM-SENSITIVE FUSION PROTEIN 2) (DNSF-2) >gi|973317|gb|AAA75044.1| (U30502) Drosophila N-ethylmaleimide-sensitive fusion protein 2 [Drosophila melanogaster] Length = 752 Score = 88.9 bits (217), Expect = 8e-17 Identities = 88/303 (29%), Positives = 145/303 (47%), Gaps = 54/303 (17%) Query: 58 KKWEEKAKNVRKRREGKNEYFDKLKALIKRSTIT--WN----DIGGLREAKKLIAQAIGL 111 +K E N++ R +GK ++++S I W+ IGGL + I + Sbjct: 191 EKAENSVLNLQGRSKGK---------IVRQSIINPDWDFGKMGIGGLDKEFNAIFRRAFA 241 Query: 112 SIAKSP-------IEPPQGILLFGPPGTGKSLLASAVANSLNATFFS-VKASDLLSKYFG 163 S P I+ +GILL+GPPGTGK+L+A + LNA V +L KY G Sbjct: 242 SRVFPPELVEQLGIKHVKGILLYGPPGTGKTLMARQIGTMLNAREPKIVNGPQILDKYVG 301 Query: 164 ESSKLISALFSLA----RQLSPS----VIFIDEVDSLTMKRVSL---DDAARRMIGTLLA 212 ES I LF+ A ++L P+ +I DE+D++ R S+ ++ LLA Sbjct: 302 ESEANIRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAICKARGSVAGNSGVHDTVVNQLLA 361 Query: 213 EMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLR--- 267 ++DG E+ + ++V+ TN +DEA+L RL +++ + LP+ V+I IH + Sbjct: 362 KIDGV-EQLNNILVIGMTNRRDMIDEALLRPGRLEVQMEISLPNEQGRVQILNIHTKRMR 420 Query: 268 ---GIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEM---------NPELSDPL 315 I DV + +A A + +SG E+ +V+ A + + +PE + L Sbjct: 421 DFNKIASDVDNNEIA--AKTKNFSGAELEGLVRAAQSTAMNRLIKADSKVHVDPEAMEKL 478 Query: 316 RVS 318 RV+ Sbjct: 479 RVT 481 >gb|AAF54995.1| (AE003702) Nsf2 gene product [Drosophila melanogaster] Length = 1113 Score = 88.9 bits (217), Expect = 8e-17 Identities = 88/303 (29%), Positives = 145/303 (47%), Gaps = 54/303 (17%) Query: 58 KKWEEKAKNVRKRREGKNEYFDKLKALIKRSTIT--WN----DIGGLREAKKLIAQAIGL 111 +K E N++ R +GK ++++S I W+ IGGL + I + Sbjct: 552 EKAENSVLNLQGRSKGK---------IVRQSIINPDWDFGKMGIGGLDKEFNAIFRRAFA 602 Query: 112 SIAKSP-------IEPPQGILLFGPPGTGKSLLASAVANSLNATFFS-VKASDLLSKYFG 163 S P I+ +GILL+GPPGTGK+L+A + LNA V +L KY G Sbjct: 603 SRVFPPELVEQLGIKHVKGILLYGPPGTGKTLMARQIGTMLNAREPKIVNGPQILDKYVG 662 Query: 164 ESSKLISALFSLA----RQLSPS----VIFIDEVDSLTMKRVSL---DDAARRMIGTLLA 212 ES I LF+ A ++L P+ +I DE+D++ R S+ ++ LLA Sbjct: 663 ESEANIRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAICKARGSVAGNSGVHDTVVNQLLA 722 Query: 213 EMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLR--- 267 ++DG E+ + ++V+ TN +DEA+L RL +++ + LP+ V+I IH + Sbjct: 723 KIDGV-EQLNNILVIGMTNRRDMIDEALLRPGRLEVQMEISLPNEQGRVQILNIHTKRMR 781 Query: 268 ---GIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEM---------NPELSDPL 315 I DV + +A A + +SG E+ +V+ A + + +PE + L Sbjct: 782 DFNKIASDVDNNEIA--AKTKNFSGAELEGLVRAAQSTAMNRLIKADSKVHVDPEAMEKL 839 Query: 316 RVS 318 RV+ Sbjct: 840 RVT 842 >sp|P46461|NSF1_DROME VESICULAR-FUSION PROTEIN NSF1 (N-ETHYLMALEIMIDE-SENSITIVE FUSION PROTEIN 1) (NEM-SENSITIVE FUSION PROTEIN 1) (DNSF-1) (COMATOSE PROTEIN) >gi|507752|gb|AAA83413.1| (U09373) N-ethylmaleimide-sensitive fusion protein [Drosophila melanogaster] Length = 745 Score = 87.8 bits (214), Expect = 2e-16 Identities = 85/304 (27%), Positives = 148/304 (47%), Gaps = 60/304 (19%) Query: 62 EKAKNVRKRREGKNEYFDKLKALIKRSTIT--WN----DIGGL-REAKKLIAQAIGLSIA 114 EKA+N +GK++ ++++S I W+ IGGL +E + +A Sbjct: 186 EKAENSSLNLQGKSK-----GKVVRQSIINPDWDFGKMGIGGLDKEFNSIFRRAFA---- 236 Query: 115 KSPIEPPQ-----------GILLFGPPGTGKSLLASAVANSLNATFFS-VKASDLLSKYF 162 S + PP+ GILL+GPPGTGK+L+A + LNA V +L KY Sbjct: 237 -SRVFPPELVEQLGCKHVKGILLYGPPGTGKTLMARQIGTMLNAREPKIVNGPQILDKYV 295 Query: 163 GESSKLISALFSLA----RQLSPS----VIFIDEVDSLTMKRVSL---DDAARRMIGTLL 211 GES + LF+ A ++L P+ +I DE+D++ +R S+ ++ LL Sbjct: 296 GESEANVRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAICKQRGSVAGNSGVHDTVVNQLL 355 Query: 212 AEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLR-- 267 ++DG ++ + ++V+ TN +DEA+L RL +++ + LP+ V+I IH + Sbjct: 356 TKIDGV-DQLNNILVIGMTNRRDMIDEALLRPGRLEVQMEISLPNEQGRVQILNIHTKRM 414 Query: 268 ----GIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEM---------NPELSDP 314 I+ DV +A A+ + +SG E+ +V+ A + + +PE + Sbjct: 415 REFNKINDDVDNKEIA--ALTKNFSGAELEGLVRAAQSSAMNRLIKADAKVTVDPEAMEK 472 Query: 315 LRVS 318 L+V+ Sbjct: 473 LKVN 476 >gb|AAF48244.1| (AE003492) comt gene product [Drosophila melanogaster] Length = 737 Score = 87.8 bits (214), Expect = 2e-16 Identities = 85/304 (27%), Positives = 148/304 (47%), Gaps = 60/304 (19%) Query: 62 EKAKNVRKRREGKNEYFDKLKALIKRSTIT--WN----DIGGL-REAKKLIAQAIGLSIA 114 EKA+N +GK++ ++++S I W+ IGGL +E + +A Sbjct: 178 EKAENSSLNLQGKSK-----GKVVRQSIINPDWDFGKMGIGGLDKEFNSIFRRAFA---- 228 Query: 115 KSPIEPPQ-----------GILLFGPPGTGKSLLASAVANSLNATFFS-VKASDLLSKYF 162 S + PP+ GILL+GPPGTGK+L+A + LNA V +L KY Sbjct: 229 -SRVFPPELVEQLGCKHVKGILLYGPPGTGKTLMARQIGTMLNAREPKIVNGPQILDKYV 287 Query: 163 GESSKLISALFSLA----RQLSPS----VIFIDEVDSLTMKRVSL---DDAARRMIGTLL 211 GES + LF+ A ++L P+ +I DE+D++ +R S+ ++ LL Sbjct: 288 GESEANVRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAICKQRGSVAGNSGVHDTVVNQLL 347 Query: 212 AEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIFKIHLR-- 267 ++DG ++ + ++V+ TN +DEA+L RL +++ + LP+ V+I IH + Sbjct: 348 TKIDGV-DQLNNILVIGMTNRRDMIDEALLRPGRLEVQMEISLPNEQGRVQILNIHTKRM 406 Query: 268 ----GIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEM---------NPELSDP 314 I+ DV +A A+ + +SG E+ +V+ A + + +PE + Sbjct: 407 REFNKINDDVDNKEIA--ALTKNFSGAELEGLVRAAQSSAMNRLIKADAKVTVDPEAMEK 464 Query: 315 LRVS 318 L+V+ Sbjct: 465 LKVN 468 >gb|AAF18300.1|AF118384_1 (AF118384) N-ethylmaleimide sensitive fusion protein [Manduca sexta] Length = 745 Score = 85.8 bits (209), Expect = 7e-16 Identities = 90/310 (29%), Positives = 145/310 (46%), Gaps = 56/310 (18%) Query: 53 LLEEAKKWEEKAKNVRKRREGKNEYFDKLKALIKRSTITWN----DIGGL-REAKKLIAQ 107 LL +A +KA+N GK + +++I W+ IGGL +E + + Sbjct: 177 LLPDASVQFDKAENSSLNLVGKAKGKQPRQSIINPD---WDFGKMGIGGLDKEFNAIFRR 233 Query: 108 AIGLSIAKSPIEPPQ-----------GILLFGPPGTGKSLLASAVANSLNATFFS-VKAS 155 A S + PP+ GILLFGPPGTGK+L+A + LNA V Sbjct: 234 AFA-----SRVFPPEVVEQLGCKHVKGILLFGPPGTGKTLMARQIGKMLNAREPKIVNGP 288 Query: 156 DLLSKYFGESSKLISALFSLA----RQLSPS----VIFIDEVDSLTMKRVSL---DDAAR 204 +L KY GES I LF+ A ++ P+ +I DE+D++ R S+ Sbjct: 289 QILDKYVGESEANIRPLFADAEEEEKRCGPNSGLHIIIFDEIDAICKARGSVGGNTGVHD 348 Query: 205 RMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVNSAVEIF 262 ++ LL+++DG ++ + ++V+ TN +DEA+L RL +++ + LPD V+I Sbjct: 349 TVVNQLLSKIDGV-DQLNNILVIGMTNRRDMIDEALLRPGRLEVQMEIGLPDEKGRVQIL 407 Query: 263 KIH------LRGIHYDVPLSRLAKEAVKRLYSGREIANVVKLATMKMLE---------EM 307 IH + I DV LA A+ + +SG E+ +V+ A + E+ Sbjct: 408 NIHTKRMREYKKIAEDVDSMELA--ALTKNFSGAELEGLVRAAQSTAMNRLIKASSKVEV 465 Query: 308 NPELSDPLRV 317 +PE + L V Sbjct: 466 DPEAMEKLMV 475 >pir||T18421 hypothetical protein C0140c - malaria parasite (Plasmodium falciparum) >gi|3647351|emb|CAB10575.1| (Z97348) PFC0140c (MAL3P1.10), N-ethylmaleimide-sensitive fusion protein, len: 783 aa; Similarity to a number of eukaryotic N-ethylmaleimide sensitive fusion proteins (NSFs). Human NSF (SW:NSF_MOUSE). BLAST score: 1577, sum P(2) = 2.4e-142, contains Pf> Length = 783 Score = 78.4 bits (190), Expect = 1e-13 Identities = 87/343 (25%), Positives = 152/343 (43%), Gaps = 66/343 (19%) Query: 40 RKIASENLSLSHILLEEAKKWEEKAKNVRKRREGKNEY-FDKLKALIKRSTITWNDIGGL 98 R I EN + + K ++K V K+ KN + F++L IG L Sbjct: 210 RGILFENTECIFTSISDGGKLCIESKKVLKQNIIKNNFNFEEL------------GIGAL 257 Query: 99 REAKKLIAQAIGLS-------IAKSPIEPPQGILLFGPPGTGKSLLASAVANSLNATFFS 151 E K I + S I + I+ +G++L+GPPGTGK+L+A + +LNA Sbjct: 258 DEEFKTIFRRTFASRIYPNYIIKQLSIKHVKGMILYGPPGTGKTLIARQIGKTLNAREPK 317 Query: 152 -VKASDLLSKYFGESSKLISALFSLARQLSPS--------VIFIDEVDSLTMKRVSLDDA 202 + ++L+KY G+S + I LF A +I +DE+D++ +R ++ + Sbjct: 318 IINGPEILNKYVGQSEENIRNLFKDAEMEYKQSGENSLLHIIILDEIDAICRQRGNVGSS 377 Query: 203 AR----RMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLPIRIYVPLPDVN 256 + ++ LL+++DG + ++++ TN +DEA+L R + I + LP+ Sbjct: 378 STGVNDSVVNQLLSKIDGVNS-LNNILLIGMTNRIDLIDEALLRPGRFELHIEISLPNKE 436 Query: 257 SAVEIFKIHLRGIHY------DVPLSRLAKEAVKRLYSGREIANVVKLATMKMLEEMNPE 310 ++I IH + + DV + LA+ +SG EI +V+ T+ E + Sbjct: 437 GRIQILNIHTKNMRMSNKLSSDVNILELAERTPN--FSGAEIEGLVR-NTVSYAFERHIN 493 Query: 311 LSDPLRVSTLKGRDLTTRPLTLDDFKYAMARIKSPITKSDVKK 353 +D T+P+ DD ITK+D K Sbjct: 494 FND------------LTKPINADDIM---------ITKNDFMK 515 >gb|AAF26780.1|AC016829_4 (AC016829) unknown protein [Arabidopsis thaliana] Length = 1293 Score = 69.5 bits (167), Expect = 6e-11 Identities = 51/191 (26%), Positives = 93/191 (47%), Gaps = 15/191 (7%) Query: 63 KAKNVRKRREGKNEY---FDKLKALIKRSTITWNDIGGLREAKKLIAQAIGL-----SIA 114 K + +KR+ G + FD++K +K I + + ++ I + + + Sbjct: 752 KRRIKQKRKAGIDPIKTAFDRMKR-VKNPPIPLKNFASIESMREEINEVVAFLQNPKAFQ 810 Query: 115 KSPIEPPQGILLFGPPGTGKSLLASAVANSLNATFFSVKASDL-LSKYFGESSKLISALF 173 + P+G+L+ G GTGK+ LA A+A +V+A +L + G+S+ + LF Sbjct: 811 EMGARAPRGVLIVGERGTGKTSLALAIAAEARVPVVNVEAQELEAGLWVGQSAANVRELF 870 Query: 174 SLARQLSPSVIFIDEVDSLTMKRVSLDDAARR----MIGTLLAEMDGFKERKDKVIVLTA 229 AR L+P +IF+++ D R ++ I LL E+DGF E++D V+++ Sbjct: 871 QTARDLAPVIIFVEDFDLFAGVRGKFVHTKQQDHESFINQLLVELDGF-EKQDGVVLMAT 929 Query: 230 TNAPWDLDEAM 240 T +DEA+ Sbjct: 930 TRNHKQIDEAL 940 >pir||S74396 hypothetical protein slr0480 - Synechocystis sp. (strain PCC 6803) >gi|1001171|dbj|BAA10314.1| (D64001) hypothetical protein [Synechocystis sp.] Length = 499 Score = 69.1 bits (166), Expect = 7e-11 Identities = 75/295 (25%), Positives = 122/295 (40%), Gaps = 35/295 (11%) Query: 13 QEEFERALSLGHYDKARLIALRCAELLRKIASENLSLSHILLEEAKKWEEKAKNVRKRRE 72 ++E+ RA ++ R + RC ++ ++++ L EEK +++R+ Sbjct: 167 RDEWSRAAQGLSMERIRRVLARCLADHGQLGADDVELM---------LEEKRQSIRQ--- 214 Query: 73 GKNEYFDKLKALIKRSTITWNDIGGLREAKKLIAQ---AIGLSIAKSPIEPPQGILLFGP 129 + D A + S DIGGL K + + A + + P+G+LL G Sbjct: 215 --TQILDFYPASERIS-----DIGGLDNLKDWLLRRGGAFSEQARRYGLPYPRGLLLAGI 267 Query: 130 PGTGKSLLASAVANSLNATFFSVKASDLLSKYFGESSKLISALFSLARQLSPSVIFIDEV 189 GTGKSL A A+A+ + + L GES + +LA L+P V +IDE+ Sbjct: 268 QGTGKSLTAKAIAHHWHLPLLRLDVGRLFGGLVGESEARTRQMINLAEALAPCVFWIDEI 327 Query: 190 DSLTMKRVSLDD--AARRMIGTLLAEMDGFKERKDKVIVLTATNAPWDLDEAML--SRLP 245 D S D R+ G + + E+ V V+ N L +L R Sbjct: 328 DKAFGSMDSHGDGGTTSRVFGAFITWL---AEKTSPVFVVATANNVQSLPPELLRKGRFD 384 Query: 246 IRIYVPLPDVNSAVEIFKIHLRGIH----YDVPLSRLAKEAVKRLYSGREIANVV 296 +V LP+ IF +HL + D + RLA E +SG EI ++ Sbjct: 385 EIFFVGLPNKTEREAIFSVHLNRLRPHKMADYDIHRLAYETPD--FSGAEIEQIL 437 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.319 0.135 0.374 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 119756089 Number of Sequences: 2977 Number of extensions: 4628545 Number of successful extensions: 20895 Number of sequences better than 1.0e-10: 495 Number of HSP's better than 0.0 without gapping: 412 Number of HSP's successfully gapped in prelim test: 83 Number of HSP's that attempted gapping in prelim test: 19265 Number of HSP's gapped (non-prelim): 665 length of query: 363 length of database: 189,106,746 effective HSP length: 60 effective length of query: 303 effective length of database: 153,197,526 effective search space: 46418850378 effective search space used: 46418850378 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.8 bits) S2: 165 (68.7 bits)