BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1801 (sgaA-like) DE:SERINE-GLYOXYLATE AMINOTRANSFERASE
related (EC 2.6.1.45) (SERINE--GLYOXYLATE AMINOTRANSFERASE)
         (383 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||H75129 probable transaminase (EC 2.6.1.-) PAB1801 [similari...   769  0.0
pir||E71001 probable transaminase (EC 2.6.1.-) PH1308 [similarit...   739  0.0
pir||G64419 probable transaminase (EC 2.6.1.-) MJ0959 [similarit...   225  6e-58
pir||F72472 probable transaminase (EC 2.6.1.-) APE2423 [similari...   217  2e-55
pir||A72257 probable transaminase (EC 2.6.1.-) TM1400 [similarit...   212  6e-54
pir||JC2256 aspartate transaminase (EC 2.6.1.1) - Methanobacteri...   210  2e-53
emb|CAB45025.1| (AL078635) putative aminotransferase [Amycolatop...   207  2e-52
pir||H69080 aspartate transaminase (EC 2.6.1.1) MTH1601 [similar...   205  6e-52
pir||S75916 probable soluble hydrogenase (EC 1.12.-.-) small cha...   184  1e-45
gi|11499012 aspartate aminotransferase (aspC) [Archaeoglobus ful...   182  8e-45
sp|P16421|DHSS_ANACY SOLUBLE HYDROGENASE 42 KD SUBUNIT (TRITIUM ...   179  4e-44
sp|P14776|DHSS_SYNP1 SOLUBLE HYDROGENASE, SMALL SUBUNIT (TRITIUM...   179  4e-44
pir||G82328 aminotransferase, class V VC0392 [imported] - Vibrio...   165  7e-40
pir||F70017 probable transaminase (EC 2.6.1.-) yurG [similarity]...   161  1e-38
dbj|BAB04481.1| (AP001509) aspartate transaminase [Bacillus halo...   159  5e-38
sp|O08374|SGAA_HYPME SERINE--GLYOXYLATE AMINOTRANSFERASE (SGAT) ...   156  3e-37
pir||G70437 soluble hydrogenase small subunit - Aquifex aeolicus...   153  3e-36
gb|AAK41188.1| Soluble hydrogenase, small subunit [Sulfolobus so...   149  4e-35
gb|AAG20505.1| (AE005122) aspartate aminotransferase; AspC1 [Hal...   145  1e-33
sp|P55819|SGAA_METEX SERINE--GLYOXYLATE AMINOTRANSFERASE (SGAT)       144  1e-33
emb|CAC17015.1| (AJ278065) putative alanine:glyoxylate aminotran...   143  2e-33
gb|AAB95218.1| (AF039000) putative serine-glyoxylate aminotransf...   142  6e-33
gb|AAK42719.1| Serine-pyruvate aminotransferase (agxT) [Sulfolob...   140  2e-32
gb|AAC26854.1| (AF063901) alanine:glyoxylate aminotransferase; t...   140  2e-32
emb|CAC12147.1| (AL445066) serine-glyoxylate aminotransferase re...   140  2e-32
sp|O25436|Y736_HELPY PUTATIVE AMINOTRANSFERASE HP0736 >gi|743410...   137  2e-31
sp|Q9ZLA7|Y736_HELPJ PUTATIVE AMINOTRANSFERASE HP0736 >gi|743410...   136  3e-31
pir||T24910 probable alanine--glyoxylate transaminase (EC 2.6.1....   136  3e-31
sp|P09139|SPYA_RAT SERINE--PYRUVATE AMINOTRANSFERASE, MITOCHONDR...   136  4e-31
gb|AAA42169.1| (M35270) mitochondrial serine:pyruvate aminotrans...   136  4e-31
pir||G75406 probable transaminase (EC 2.6.1.-) DR1350 [similarit...   136  5e-31
sp|P31030|SPYA_RABIT SERINE--PYRUVATE AMINOTRANSFERASE (SPT) (AL...   135  7e-31
sp|P31029|SPYA_CALJA SERINE--PYRUVATE AMINOTRANSFERASE, MITOCHON...   133  4e-30
gb|AAF46168.1| (AE003437) Spat gene product [Drosophila melanoga...   131  1e-29
gi|7709978 alanine-glyoxylate aminotransferase; alanine-glyoxyla...   130  2e-29
pir||A75451 probable soluble hydrogenase (EC 1.12.-.-) small cha...   129  5e-29
gb|AAG26467.1|AF285774_7 (AF285774) putative 2-aminoethylphospho...   125  8e-28
prf||1704252A Ala/glyoxylate aminotransferase [Homo sapiens]          124  2e-27
gi|4557289 alanine-glyoxylate aminotransferase; Alanine-glyoxyla...   123  2e-27
sp|P41689|SPYA_FELCA SERINE--PYRUVATE AMINOTRANSFERASE, MITOCHON...   123  3e-27
dbj|BAA02632.1| (D13368) alanine:glyoxylate aminotransferase [Ho...   122  5e-27
emb|CAA71715.1| (Y10727) alanine--glyoxylate aminotransferase [C...   122  7e-27
pir||H82437 2-aminoethylphosphonate--pyruvate aminotransferase (...   120  2e-26
pir||B83482 2-aminoethylphosphonate:pyruvate aminotransferase PA...   118  8e-26
pir||T46947 2-aminoethylphosphonate--pyruvate aminotransferase (...   110  2e-23
gb|AAF19555.1|AC005761_3 (AC005761) 2-aminoethylphosphonate:pyru...   110  2e-23
gb|AAF28367.1|AC005766_1 (AC005766) 2-aminoethylphosphonate:pyru...   110  2e-23
gb|AAF27941.1|AC005767_2 (AC005767) 2-aminoethylphosphonate:pyru...   109  4e-23
gi|6321079 Yfl030wp [Saccharomyces cerevisiae] >gi|1175939|sp|P4...   108  9e-23
gb|AAA03070.1| (L01470) aminotransferase and dihydrorhizobitoxin...   101  1e-20
pir||C47293 serine--pyruvate aminotransferase homolog RtxA - Bra...   101  1e-20
emb|CAA60241.1| (X86528) aspC [Clostridium perfringens]                93  6e-18
emb|CAA58024.1| (X82783) serine:pyruvate aminotransferase [Droso...    80  3e-14
emb|CAC08322.1| (AL392149) putative aminotransferase [Streptomyc...    76  5e-13
gb|AAG13347.1|AF266227_1 (AF266227) serine-pyruvate aminotransfe...    76  8e-13

>pir||H75129 probable transaminase (EC 2.6.1.-) PAB1801 [similarity] -
           Pyrococcus abyssi (strain Orsay)
           >gi|5458264|emb|CAB49753.1| (AJ248285) SERINE-GLYOXYLATE
           AMINOTRANSFERASE related (EC 2.6.1.45)
           (SERINE--GLYOXYLATE AMINOTRANSFERASE) [Pyrococcus
           abyssi]
           Length = 383
           
 Score =  769 bits (1965), Expect = 0.0
 Identities = 383/383 (100%), Positives = 383/383 (100%)

Query: 1   MEFEDAFKEVYEMVKPKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLR 60
           MEFEDAFKEVYEMVKPKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLR
Sbjct: 1   MEFEDAFKEVYEMVKPKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLR 60

Query: 61  DFLEVKKGEVLLVPSSGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVV 120
           DFLEVKKGEVLLVPSSGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVV
Sbjct: 61  DFLEVKKGEVLLVPSSGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVV 120

Query: 121 LEYEPGKAVKPEDLDEALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDA 180
           LEYEPGKAVKPEDLDEALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDA
Sbjct: 121 LEYEPGKAVKPEDLDEALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDA 180

Query: 181 VSAMGGADIKFDKWELDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPL 240
           VSAMGGADIKFDKWELDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPL
Sbjct: 181 VSAMGGADIKFDKWELDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPL 240

Query: 241 YIKYLKEKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLG 300
           YIKYLKEKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLG
Sbjct: 241 YIKYLKEKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLG 300

Query: 301 ILAEPGYESPTITAVLTPEGIKGDEVYEAMRKRGFELAKGYGSVREKTFRIGHMGYMKFE 360
           ILAEPGYESPTITAVLTPEGIKGDEVYEAMRKRGFELAKGYGSVREKTFRIGHMGYMKFE
Sbjct: 301 ILAEPGYESPTITAVLTPEGIKGDEVYEAMRKRGFELAKGYGSVREKTFRIGHMGYMKFE 360

Query: 361 DIQEMLDNLKEVIEELKKQKGIN 383
           DIQEMLDNLKEVIEELKKQKGIN
Sbjct: 361 DIQEMLDNLKEVIEELKKQKGIN 383


>pir||E71001 probable transaminase (EC 2.6.1.-) PH1308 [similarity] - Pyrococcus
           horikoshii >gi|3257730|dbj|BAA30413.1| (AP000006) 386aa
           long hypothetical serine aminotransferase [Pyrococcus
           horikoshii]
           Length = 386
           
 Score =  739 bits (1888), Expect = 0.0
 Identities = 363/383 (94%), Positives = 378/383 (97%)

Query: 1   MEFEDAFKEVYEMVKPKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLR 60
           MEFE+AFKEVYEMVKPKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVH+DTVERLR
Sbjct: 4   MEFEEAFKEVYEMVKPKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHMDTVERLR 63

Query: 61  DFLEVKKGEVLLVPSSGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVV 120
           +FLEV+KGEVLLVPSSGTGIMEASIRNGV+KGGKVLVTIIGAFGKRYKEVVE+NGRKAVV
Sbjct: 64  EFLEVEKGEVLLVPSSGTGIMEASIRNGVSKGGKVLVTIIGAFGKRYKEVVESNGRKAVV 123

Query: 121 LEYEPGKAVKPEDLDEALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDA 180
           LEYEPGKAVKPEDLD+AL+KNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDA
Sbjct: 124 LEYEPGKAVKPEDLDDALRKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDA 183

Query: 181 VSAMGGADIKFDKWELDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPL 240
           VSAMGGADIKFDKW LDVVFSSSQKAFGVPPGLAIGAFSERF+EIAEKMPERGWYFDIPL
Sbjct: 184 VSAMGGADIKFDKWGLDVVFSSSQKAFGVPPGLAIGAFSERFLEIAEKMPERGWYFDIPL 243

Query: 241 YIKYLKEKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLG 300
           Y+KYLKEKESTPSTPPMPQVFG+NV LRIIEKMGGKEKWLEMYEKRAKMVREGV+EIGL 
Sbjct: 244 YVKYLKEKESTPSTPPMPQVFGINVALRIIEKMGGKEKWLEMYEKRAKMVREGVREIGLD 303

Query: 301 ILAEPGYESPTITAVLTPEGIKGDEVYEAMRKRGFELAKGYGSVREKTFRIGHMGYMKFE 360
           ILAEPG+ESPTITAVLTP GIKGDEVYEAMRKRGFELAKGYGSV+EKTFRIGHMGYMKFE
Sbjct: 304 ILAEPGHESPTITAVLTPPGIKGDEVYEAMRKRGFELAKGYGSVKEKTFRIGHMGYMKFE 363

Query: 361 DIQEMLDNLKEVIEELKKQKGIN 383
           DIQEMLDNL+EVI ELKKQKGIN
Sbjct: 364 DIQEMLDNLREVINELKKQKGIN 386


>pir||G64419 probable transaminase (EC 2.6.1.-) MJ0959 [similarity] -
           Methanococcus jannaschii >gi|1591623|gb|AAB98961.1|
           (U67539) aspartate aminotransferase (aspC)
           [Methanococcus jannaschii]
           Length = 385
           
 Score =  225 bits (568), Expect = 6e-58
 Identities = 126/362 (34%), Positives = 206/362 (56%), Gaps = 4/362 (1%)

Query: 17  KYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPSS 76
           K  L   GP    PEVL  M + +  HR+K+Y  +  DT+E+L+    + + +  L+  S
Sbjct: 7   KKLLMIPGPTMVPPEVLNAMALPVIGHRTKDYSNLLEDTIEKLKKVF-ITENDTFLITGS 65

Query: 77  GTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLDE 136
           GT  M+ +I N + +G KVL  + G FG+R+  +V+    +A+ L+ E G   +PE + E
Sbjct: 66  GTAAMDMAISNIIKRGDKVLNIVTGNFGERFANIVKAYKGEAIRLDVEWGDMAEPEAVKE 125

Query: 137 ALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWEL 196
            L K  D++AVT+ +NETSTG  NP+ E+ +V K++D L  VD VS++GG  +  DK+ +
Sbjct: 126 ILDKYDDIKAVTVVHNETSTGARNPIKEIGEVVKDYDALYIVDTVSSLGGDYVNVDKFHI 185

Query: 197 DVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPER-GWYFDIPLYIKYLKEKESTPSTP 255
           D+  + SQK    PPGLA    SE+  E+ +K  ++ G+Y D+  Y KY +EK+ TP TP
Sbjct: 186 DICVTGSQKCLAAPPGLAAITVSEKAWEVIKKNDDKVGFYLDLLAYKKYYEEKKQTPYTP 245

Query: 256 PMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAEPGYESPTITAV 315
            +   + LNV L ++ +  G E  ++ +E+ AK  R G++ +G+ + A+    S T+T+ 
Sbjct: 246 SVNLTYALNVALDLVLE-EGIENRVKRHERLAKATRAGLEAMGIELFAKERARSVTVTSA 304

Query: 316 LTPEGIKGDEVYEAM-RKRGFELAKGYGSVREKTFRIGHMGYMKFEDIQEMLDNLKEVIE 374
             PEGI+  +    +  K    +A G   +  K FRIGHMG    +++   L  ++  ++
Sbjct: 305 KYPEGIEDSKFRGILSNKYNIVVAGGQKHLAGKIFRIGHMGICGEKEVLATLACVELALK 364

Query: 375 EL 376
           EL
Sbjct: 365 EL 366


>pir||F72472 probable transaminase (EC 2.6.1.-) APE2423 [similarity] - Aeropyrum
           pernix (strain K1) >gi|5106127|dbj|BAA81438.1|
           (AP000064) 382aa long hypothetical soluble hydrogenase
           subunit [Aeropyrum pernix]
           Length = 382
           
 Score =  217 bits (547), Expect = 2e-55
 Identities = 128/361 (35%), Positives = 199/361 (54%), Gaps = 10/361 (2%)

Query: 20  LFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPSSGTG 79
           L   GP    PEVL  M   + SH S ++ ++H +TV  L+       G+V L+P SG+ 
Sbjct: 5   LMIPGPTPVDPEVLLAMARPVISHTSPDFDEIHGETVSMLQKLFRTS-GKVFLLPGSGSL 63

Query: 80  IMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLDEALK 139
            ME ++R+   +G + LV   G FG  ++ ++ + G    V+E   G+     D++EAL 
Sbjct: 64  GMEFAVRSVAGRGSRALVLKAGYFGGYFERILRSLGASVTVVESPVGRGFTGADVEEALD 123

Query: 140 KNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWELDVV 199
           +  DV+ V + + ETST V NP+ E+A V K++   + VD ++++GG D++ D+W +DV 
Sbjct: 124 RAGDVDVVFVQHVETSTSVANPVREIAGVVKKNGARLVVDGIASVGGMDLRLDEWGVDVA 183

Query: 200 FSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPLYIKYLKEKESTPS---TPP 256
            + SQKA   PPGLAI AFS  +    EK    G YFD   ++   +E EST +   TP 
Sbjct: 184 LTGSQKALSTPPGLAIVAFSSEYSVELEKREPSGIYFD---FLSLSREMESTRNYHITPA 240

Query: 257 MPQVFGLNVVLRIIEKMG-GKEKWLEMYEKRAKMVREGVKEIGLGILAEPGYESPTITAV 315
           +  VF LN  L+ I  +G G E   E +   A+     ++ +GL ++AE  + + T+TAV
Sbjct: 241 VNLVFALNASLKRI--LGEGLENRFERHRVLARAFTRAMEALGLRLVAEEPFRAWTVTAV 298

Query: 316 LTPEGIKGDEVYEAMRKRGFELAKGYGSVREKTFRIGHMGYMKFEDIQEMLDNLKEVIEE 375
             P+GI     Y  MRKRG E+A G G ++ K FR+GHMG +   D+   +  ++  + E
Sbjct: 299 YLPQGIDWSRFYSVMRKRGVEVAGGLGGLKGKIFRVGHMGEVDANDLIATIAAIERSLVE 358

Query: 376 L 376
           L
Sbjct: 359 L 359


>pir||A72257 probable transaminase (EC 2.6.1.-) TM1400 [similarity] - Thermotoga
           maritima (strain MSB8)
           >gi|4981964|gb|AAD36471.1|AE001793_1 (AE001793)
           aspartate aminotransferase, putative [Thermotoga
           maritima]
           Length = 384
           
 Score =  212 bits (534), Expect = 6e-54
 Identities = 126/362 (34%), Positives = 200/362 (54%), Gaps = 10/362 (2%)

Query: 17  KYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPSS 76
           K+ +   GP     ++L     +   HR+ ++  +  +T+E  +   + K   V    S+
Sbjct: 7   KHYIMAPGPTPVPNDILTEGAKETIHHRTPQFVSIMEETLESAKYIFQTKHN-VYAFAST 65

Query: 77  GTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLDE 136
           GTG MEA++ N V+ G KV+V + G FG+R++E+ +  G   V +  E G AV PE ++E
Sbjct: 66  GTGAMEAAVANLVSPGDKVIVVVAGKFGERWRELCQAYGADIVEIALEWGDAVTPEQIEE 125

Query: 137 ALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWEL 196
           AL KNPD + V  TY+ETSTG +  L  +A+V KE D ++  DAVSA+G   +K D+W +
Sbjct: 126 ALNKNPDAKVVFTTYSETSTGTVIDLEGIARVTKEKDVVLVTDAVSALGAEPLKMDEWGV 185

Query: 197 DVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPLYIKYLKEKESTPSTPP 256
           D+V + SQK   +PPGLA+ + +++   + EK     +YFD+     Y K     P TP 
Sbjct: 186 DLVVTGSQKGLMLPPGLALISLNDKAWGLVEKSRSPRYYFDLR---AYRKSYPDNPYTPA 242

Query: 257 MPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAE-PGYESPTITAV 315
           +  ++ L   L++I++ G +  W E +       R  VK +GL +L++ PG     +TAV
Sbjct: 243 VNMIYMLRKALQMIKEEGIENVW-ERHRILGDATRAAVKALGLELLSKRPG---NVVTAV 298

Query: 316 LTPEGIKGDEVYEAMR-KRGFELAKGYGSVREKTFRIGHMGYMKFEDIQEMLDNLKEVIE 374
             PEGI G ++ + MR K G  +A G   ++ K FRI H+GYM   D    +  L+  ++
Sbjct: 299 KVPEGIDGKQIPKIMRDKYGVTIAGGQAKLKGKIFRIAHLGYMSPFDTITAISALELTLK 358

Query: 375 EL 376
           EL
Sbjct: 359 EL 360


>pir||JC2256 aspartate transaminase (EC 2.6.1.1) - Methanobacterium
           thermoformicicum >gi|704449|dbj|BAA05953.1| (D28763)
           aspartate aminotransferase [Methanobacterium
           thermoformicicum]
           Length = 385
           
 Score =  210 bits (530), Expect = 2e-53
 Identities = 121/360 (33%), Positives = 197/360 (54%), Gaps = 5/360 (1%)

Query: 20  LFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPSSGTG 79
           L   GP      VL+ M   + +HRS  + K+  +T E + D         LL   SGT 
Sbjct: 6   LMIPGPTRVAQRVLKAMSENIVNHRSALFGKILSETSEMMSDVFRTNNKSYLLT-GSGTA 64

Query: 80  IMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLDEALK 139
            MEA+I N +  G KVL  + G FG+R+ ++VE  G +++ ++ E GKAV P+++  AL+
Sbjct: 65  AMEAAIANIIEPGDKVLNVVGGKFGQRFSQIVEAFGGESIRIDVEWGKAVNPDEIGYALE 124

Query: 140 KNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWELDVV 199
           +N D++AVT+ +NETSTGV NP+ E+ K+  ++D L  VD VS++GG ++  D + +D+ 
Sbjct: 125 ENDDIKAVTVVHNETSTGVANPIKEIGKIMSDYDALYVVDTVSSLGGDEVDVDGYGIDIC 184

Query: 200 FSSSQKAFGVPPGLAIGAFSERFIEIAEKMP-ERGWYFDIPLYIKY-LKEKESTPSTPPM 257
            + SQK    PPG+A    S+      E +   R +Y ++  Y K    E   TP TP +
Sbjct: 185 VTGSQKCLAAPPGMAAITLSDDAWSAVEGVSNSRTYYLNLKKYRKSGDAEPPETPYTPAV 244

Query: 258 PQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAEPGYESPTITAVLT 317
             ++ ++  L++I + G   + ++ ++  A+  R  +K +GL +  +    S T+TAV  
Sbjct: 245 SLIYAMHEPLKVIMEEGLNNR-IKRHKLAAEATRNAIKALGLELFPDESVSSTTVTAVRL 303

Query: 318 PEGIKGDEVYEAMR-KRGFELAKGYGSVREKTFRIGHMGYMKFEDIQEMLDNLKEVIEEL 376
           PEG+   E+   MR K   ELA G   ++ K FRIGHMG +   ++   +  L+  + EL
Sbjct: 304 PEGVTDGELRGTMRNKYHVELAGGQDHLKGKIFRIGHMGNITHRELITTISGLEMTLREL 363


>emb|CAB45025.1| (AL078635) putative aminotransferase [Amycolatopsis orientalis]
           Length = 362
           
 Score =  207 bits (521), Expect = 2e-52
 Identities = 123/354 (34%), Positives = 187/354 (52%), Gaps = 5/354 (1%)

Query: 23  AGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPSSGTGIME 82
           +GP    P V   +   M SHRS  +R +  + +  L          +L    SGTG +E
Sbjct: 6   SGPTPLPPRVRAALSTDMISHRSTAFRDIVAEVLAGLTPVFG-DPATILPFTCSGTGGLE 64

Query: 83  ASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLDEALKKNP 142
           A++ N V  G +V+V  IG FG R  E+    G    V+E   G+A  P +L   L++  
Sbjct: 65  AAVVNTVRPGQRVVVVSIGYFGTRMAEIARMAGLDIEVIEVPWGQAADPGELQAVLRRLR 124

Query: 143 DVEAVTITYNETSTGVLNPLPELAKVAKE-HDKLVFVDAVSAMGGADIKFDKWELDVVFS 201
           DV AV +T+NETSTGVLNPLPEL +V +E  D L+ VD VS++G   ++   W +DV   
Sbjct: 125 DVAAVLVTHNETSTGVLNPLPELCRVVRESSDALLIVDVVSSVGATPVRMRDWGIDVAVG 184

Query: 202 SSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPLYIKYLKEKESTPSTPPMPQVF 261
            SQKA   PPGLA+   S R +  A   P R +YFD     + + E+ +T  TP +P   
Sbjct: 185 VSQKALMSPPGLALLGVSSRALTAAAANPARRYYFDFTAMARAV-EENTTTYTPAIPVFH 243

Query: 262 GLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAEPGYESPTITAVLTPEGI 321
            L   LR+I  + G ++ L  +++ ++  R G+ ++GL   A+  Y SPT+T+   P  +
Sbjct: 244 ALQTALRMI-SVEGWDRVLARHQRLSEQCRSGLADLGLAFAADQPYASPTVTSFFVPADM 302

Query: 322 KGDEVYEAMR-KRGFELAKGYGSVREKTFRIGHMGYMKFEDIQEMLDNLKEVIE 374
           +  +V E M  +   ++A G    ++   RIGHMGY+   D+  +L  L  V++
Sbjct: 303 RASDVRERMAVEHKVQVASGRAKWKDSVLRIGHMGYVNENDVAHVLAALGAVLD 356


>pir||H69080 aspartate transaminase (EC 2.6.1.1) MTH1601 [similarity] -
           Methanobacterium thermoautotrophicum (strain Delta H)
           >gi|2622725|gb|AAB86074.1| (AE000919) aspartate
           aminotransferase [Methanobacterium thermoautotrophicum]
           Length = 387
           
 Score =  205 bits (517), Expect = 6e-52
 Identities = 116/360 (32%), Positives = 194/360 (53%), Gaps = 5/360 (1%)

Query: 20  LFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPSSGTG 79
           L   GP      VL+ M   + +HRS  + ++  +T E + D         LL   SGT 
Sbjct: 8   LMIPGPTRVAQRVLKAMSENIVNHRSALFGRILTETTEMMSDVFRTSNKSYLLT-GSGTA 66

Query: 80  IMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLDEALK 139
            MEA++ N +  G K+L  + G FG+R+ ++VE  G +++ ++ E GKAV P+D+   L+
Sbjct: 67  AMEAAVANIIEPGDKILNVVGGKFGQRFAQIVEAFGGESITIDVEWGKAVNPDDIGYTLE 126

Query: 140 KNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWELDVV 199
           +N D++AVT+ +NETSTGV NP+ E+ K+  ++D L  VD VS++GG ++  + + +D+ 
Sbjct: 127 ENDDIKAVTVVHNETSTGVANPIREIGKIMDDYDALYIVDTVSSLGGDEVDVESYGIDIC 186

Query: 200 FSSSQKAFGVPPGLAIGAFSERFIEIAEKMPE-RGWYFDIPLYIKY-LKEKESTPSTPPM 257
            + SQK    PPG+A    S     + E +   R +Y ++  Y K    E   TP TP +
Sbjct: 187 VTGSQKCLAAPPGMAAITLSNDAWRVIEAVDNPRTYYLNLKKYRKSGDAEPPETPYTPAV 246

Query: 258 PQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAEPGYESPTITAVLT 317
             ++ ++  L++I + G   + ++ ++  A+  R  VK + L +  +    S T+TAV  
Sbjct: 247 SLIYAMHEALKVIMEEGLSNR-IKRHKIAAEATRNAVKALDLELFPDEAVSSTTVTAVNL 305

Query: 318 PEGIKGDEVYEAMR-KRGFELAKGYGSVREKTFRIGHMGYMKFEDIQEMLDNLKEVIEEL 376
           PEG+   E+   MR K   ELA G   ++ + FRIGHMG +   ++      L+  + EL
Sbjct: 306 PEGVTDGELRGTMRNKYHVELAGGQDHLKGRIFRIGHMGNITHRELITTFSALEMTLREL 365


>pir||S75916 probable soluble hydrogenase (EC 1.12.-.-) small chain [similarity]
           - Synechocystis sp. (strain PCC 6803)
           >gi|1653461|dbj|BAA18375.1| (D90913) soluble hydrogenase
           42 kD subunit [Synechocystis sp.]
           Length = 384
           
 Score =  184 bits (463), Expect = 1e-45
 Identities = 122/364 (33%), Positives = 195/364 (53%), Gaps = 8/364 (2%)

Query: 17  KYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPSS 76
           K  L   GP     +VL  M      HRS ++ K+  +    L+ +L   + +VL++ +S
Sbjct: 4   KQMLMIPGPTPVPEKVLLAMAKHPIGHRSGDFSKIIAELTANLK-WLHQTENDVLMLTTS 62

Query: 77  GTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLDE 136
           GTG MEASI N ++ G +VLV   G FG R+ +V +T G     ++ E GKA+ P D   
Sbjct: 63  GTGAMEASIINFLSPGDRVLVGNNGKFGDRWVKVAKTFGLAVEEIKAEWGKALDPNDFKT 122

Query: 137 ALKKNPD--VEAVTITYNETSTGVLNPLPELAKVAKEH-DKLVFVDAVSAMGGADIKFDK 193
            L+ + D  ++A+ IT++ETSTGVLN L  +   AK H   L+ VDAV+++G   +  D 
Sbjct: 123 LLEADSDKTIKALIITHSETSTGVLNDLAAINAAAKAHGGALMIVDAVTSLGATPVAIDD 182

Query: 194 WELDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPLYIKYLKEKESTPS 253
             LDVV S SQK + +PPGL   + S +  +  E      +Y D+  Y K   +++S+P 
Sbjct: 183 LGLDVVASGSQKGYMIPPGLGFVSVSAKAWQAYETATIPRFYLDLKKY-KKSTDEDSSPF 241

Query: 254 TPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAEPGYESPTIT 313
           TPP+  ++GL   L+++ K  G +     +++     R  +K + L + A     S  IT
Sbjct: 242 TPPINLMYGLQASLQMM-KAEGLDAIFTRHQRHTNATRGAMKALNLPLFAPDNAASNAIT 300

Query: 314 AVLTPEGIKGDEVYEAMRKR-GFELAKGYGSVREKTFRIGHMGYMKFEDIQEMLDNLKEV 372
           AV  P G++ +++   MRK+    +A G   ++ K FRIGH+G++   DI   +  L+  
Sbjct: 301 AV-APLGVEAEKIRSTMRKKFDIAMAGGQDHLKGKIFRIGHLGFVCDRDILSCIGALEAT 359

Query: 373 IEEL 376
           + EL
Sbjct: 360 LIEL 363


>gi|11499012 aspartate aminotransferase (aspC) [Archaeoglobus fulgidus]
           >gi|7434112|pir||H69426 probable transaminase (EC
           2.6.1.-) AF1417 [similarity] - Archaeoglobus fulgidus
           >gi|2649155|gb|AAB89830.1| (AE001006) aspartate
           aminotransferase (aspC) [Archaeoglobus fulgidus]
           Length = 372
           
 Score =  182 bits (456), Expect = 8e-45
 Identities = 124/352 (35%), Positives = 193/352 (54%), Gaps = 16/352 (4%)

Query: 20  LFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPSSGTG 79
           L   GPV     ++  M  QM  HR+ ++  +    VE+LR+    K G++ L+  SGT 
Sbjct: 3   LMIPGPVQLHERIIRAMARQMIGHRTADFSAIMEFCVEKLREIFGTK-GDICLISGSGTA 61

Query: 80  IMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLDEALK 139
            MEA+I +  ++  K+     G FG+R  ++ E   +   V +   G++ + + + EAL 
Sbjct: 62  GMEAAIAS-FSRVKKIATLENGKFGERLGDIAERYTQVERV-KVPWGESFELDAVKEALD 119

Query: 140 KNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWELDVV 199
                EAV   +NETSTG+LNP  E+AK+AKE+D LV +DA+++ GG  +K D+W +DV 
Sbjct: 120 NG--CEAVAFVHNETSTGILNPAKEIAKLAKEYDALVIMDAITSAGGDYVKMDEWGVDVA 177

Query: 200 FSSSQKAFGVPPGLAIGAFSERFIEIA-EKMPERGWYFDIPLYIKYLKEKESTPSTPPMP 258
              SQK  G PPGLA  A SE+  +   E+ P   +Y D+  Y K LK+ + TP TP +P
Sbjct: 178 IVGSQKCLGAPPGLAAVAVSEKAWDYYNERCP---YYLDLAAYRKKLKDMQ-TPYTPAVP 233

Query: 259 QVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGI---LAEPGYESPTITAV 315
             F L   L+II++ G  E  ++ +   +  VR+   E GL +   L +    S T+TA+
Sbjct: 234 LFFALAEALKIIDEEG-LENRIQRHRILSAAVRKWAVEAGLELFPNLNKYSSYSNTVTAI 292

Query: 316 LTPEGIKGDEVYEAMRKR-GFELAKGYGSVREKTFRIGHMGYM-KFEDIQEM 365
             PEG+   E+   ++K  G  ++ G G ++ K FRIG MG + KFE +  +
Sbjct: 293 KMPEGVSDSELRGTLKKEYGILVSGGQGELKGKIFRIGTMGNVGKFETVSTL 344


>sp|P16421|DHSS_ANACY SOLUBLE HYDROGENASE 42 KD SUBUNIT (TRITIUM EXCHANGE SUBUNIT)
           >gi|97676|pir||S07767 soluble hydrogenase (EC 1.12.-.-)
           small chain - Anabaena cylindrica
           >gi|38752|emb|CAA35518.1| (X17482) soluble hydrogenase
           subunit (AA 1-383) [Anabaena cylindrica]
           Length = 383
           
 Score =  179 bits (450), Expect = 4e-44
 Identities = 118/364 (32%), Positives = 193/364 (52%), Gaps = 8/364 (2%)

Query: 17  KYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPSS 76
           K  L   GP       L  +      HR+ E+  +  +  + L+ +L   + +VL++  S
Sbjct: 4   KLMLMIPGPTPVPEAALLALAKHPIGHRTSEFSNMMGEVTQNLK-WLHQTESDVLMLNVS 62

Query: 77  GTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLDE 136
           GTG +EA + N ++ G ++LV   G FG+R+ EV +  G     +  E G+ + P+   +
Sbjct: 63  GTGAVEAGMINFLSPGDRILVGSNGKFGERWVEVGQAFGLNVEAITAEWGQPLDPDKFAQ 122

Query: 137 ALK--KNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDK-LVFVDAVSAMGGADIKFDK 193
            L+   N +++AV IT++ETSTGV+N L  +    KEH + L+ VDAV+++G  ++  D 
Sbjct: 123 KLQADTNKEIKAVIITHSETSTGVINDLVAINSHVKEHGQALIIVDAVTSLGAYNVPVDA 182

Query: 194 WELDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPLYIKYLKEKESTPS 253
             LDVV S SQK + +PPGL   + S +  E  +      +Y D+  Y K    K +TP 
Sbjct: 183 LGLDVVASGSQKGYMIPPGLGFVSVSPKAWEAYKTAKLPKYYLDLGKYRK-ATAKNTTPF 241

Query: 254 TPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAEPGYESPTIT 313
           TPP+  +  L+  L +++K  G E     +E++    R  +K + L + A     SP IT
Sbjct: 242 TPPVNLMVALHTTLGMMKK-EGLESIFTRHERQKNATRAAMKALNLPLFAADECASPAIT 300

Query: 314 AVLTPEGIKGDEVYEAMRKR-GFELAKGYGSVREKTFRIGHMGYMKFEDIQEMLDNLKEV 372
           AV TP G++ D++   M+KR    LA G   +  K FR+GH+G++   DI   + +L+ V
Sbjct: 301 AVATP-GMEADKIRSLMKKRFDIALAGGQDHLSNKIFRVGHLGFVSDRDILSCIASLEVV 359

Query: 373 IEEL 376
           + EL
Sbjct: 360 LLEL 363


>sp|P14776|DHSS_SYNP1 SOLUBLE HYDROGENASE, SMALL SUBUNIT (TRITIUM EXCHANGE SUBUNIT)
           >gi|66656|pir||HQYCSS soluble hydrogenase (EC 1.12.-.-)
           small chain - Synechococcus sp. (strain PCC 6716)
           >gi|48054|emb|CAA34644.1| (X16658) small subunit of
           soluble hydrogenase (AA 1-384) [Synechococcus sp.]
           Length = 384
           
 Score =  179 bits (450), Expect = 4e-44
 Identities = 118/367 (32%), Positives = 191/367 (51%), Gaps = 8/367 (2%)

Query: 14  VKPKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLV 73
           ++ K  L   GP      VL  +      HRS E+ ++       ++ +L   + EVL++
Sbjct: 1   MQDKAMLMIPGPTPVPESVLLSLGKHPIGHRSGEFSQIMAAMTAGIK-WLHQTQNEVLIL 59

Query: 74  PSSGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPED 133
            +SGTG MEA I N ++ G +V+V   G FG R+ EV +  G     +    G+ + P+D
Sbjct: 60  AASGTGAMEAGIINFLSAGDRVVVGCNGKFGDRWGEVCDAYGLTTERISAPWGQPLNPDD 119

Query: 134 LDEALK--KNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDK-LVFVDAVSAMGGADIK 190
               L   +    +AV +T++ETSTGV+N L  + +  K H + L+ VDAV+++G   + 
Sbjct: 120 FKAVLDGHRQKPSKAVIVTHSETSTGVINDLEAINRHVKAHGQALIIVDAVTSLGAVSVP 179

Query: 191 FDKWELDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPLYIKYLKEKES 250
            D+W LDVV S SQK + +PPGLA  + S +  E  +      +Y D+  Y K    K +
Sbjct: 180 IDEWGLDVVGSGSQKGYMIPPGLAFVSVSPKAWEAYKTATLPKFYLDLGKYRKD-AAKHT 238

Query: 251 TPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAEPGYESP 310
           TP TPP+   F L   L +++   G E   + +++  +  R  +K + L + A     SP
Sbjct: 239 TPFTPPVNLFFALKTALEMMQ-AEGLEAIFQRHQRLMQATRAAMKALNLPLYAADSCASP 297

Query: 311 TITAVLTPEGIKGDEVYEAMRKR-GFELAKGYGSVREKTFRIGHMGYMKFEDIQEMLDNL 369
            ITAV  P+G++ + +   M+KR    LA G   ++ + FRIGH+G++   DI   +  L
Sbjct: 298 AITAV-APQGVEAENIRSLMKKRFDIALAGGQDHLKGQIFRIGHLGFVGDRDILAAVSAL 356

Query: 370 KEVIEEL 376
           + V+ EL
Sbjct: 357 EAVLAEL 363


>pir||G82328 aminotransferase, class V VC0392 [imported] - Vibrio cholerae
           (group O1 strain N16961) >gi|9654812|gb|AAF93565.1|
           (AE004127) aminotransferase, class V [Vibrio cholerae]
           Length = 372
           
 Score =  165 bits (414), Expect = 7e-40
 Identities = 108/368 (29%), Positives = 183/368 (49%), Gaps = 7/368 (1%)

Query: 10  VYEMVKPKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGE 69
           +   + P   L   GP A  P+VL+ +      H    +  +  +  + L+   + +   
Sbjct: 3   IRSFIPPHRILMGPGPSAISPQVLQALSRPTVGHLDPLFIGMMDELKQLLKYAFQTENEF 62

Query: 70  VLLVPSSGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAV 129
            + V + G+  MEA   N V  G KV+V   G FG+R ++     G + VV++ E G  V
Sbjct: 63  TIAVSAPGSAGMEACFVNLVEPGDKVIVCRNGVFGERMRDNAVRCGAEVVVVDDEWGCPV 122

Query: 130 KPEDLDEALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADI 189
             E +   + ++PD + +     ETSTG L+    L  +AK+H  L  VDAV+++GG  +
Sbjct: 123 SVEKVQATIDEHPDAKILAFVQAETSTGALSDAQALGALAKQHGLLTIVDAVTSLGGVPL 182

Query: 190 KFDKWELDVVFSSSQKAFGVPPGLAIGAFSERFIE--IAEKMPERGWYFDIPLYIKYLK- 246
             D+W+LD V+S SQK     PGLA   FS R IE   + K P + W+ D  L + Y   
Sbjct: 183 LVDEWQLDAVYSGSQKCLSCVPGLAPLTFSPRAIEKIQSRKTPIQSWFLDQSLVLGYWSG 242

Query: 247 -EKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAEP 305
             K S   T P+  ++ L+  L ++++ G +  W + +    + +++G++++G   +   
Sbjct: 243 AGKRSYHHTAPVNSLYALHEALLLLQQEGLEHAW-QRHRLMHEKLKQGLEQLGFQFVVAE 301

Query: 306 GYESPTITAVLTPEGIKGDEV-YEAMRKRGFELAKGYGSVREKTFRIGHMGY-MKFEDIQ 363
            Y  P + A+  PEGI+  +V    + +   E+  G G++  K +RIG MGY  + E+I 
Sbjct: 302 PYRLPQLNAIYVPEGIEEAKVRSHLLNEYNLEIGAGLGALAGKAWRIGVMGYGARSENIA 361

Query: 364 EMLDNLKE 371
             L  L+E
Sbjct: 362 LCLRALEE 369


>pir||F70017 probable transaminase (EC 2.6.1.-) yurG [similarity] - Bacillus
           subtilis >gi|2635749|emb|CAB15242.1| (Z99120) similar to
           aspartate aminotransferase [Bacillus subtilis]
           Length = 416
           
 Score =  161 bits (403), Expect = 1e-38
 Identities = 110/394 (27%), Positives = 183/394 (45%), Gaps = 28/394 (7%)

Query: 12  EMVKPKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVL 71
           E+  P   + T GPV   P VL +M   +       +  +  +T+E LR+  + K     
Sbjct: 6   ELCTPLRTIMTPGPVEVDPRVLRVMSTPVVGQFDPAFTGIMNETMEMLRELFQTKNRWAY 65

Query: 72  LVPSSGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKP 131
            +  +    +EA + + +     VL+ I G FG    E+ E  G    +LE E G    P
Sbjct: 66  PIDGTSRAGIEAVLASVIEPEDDVLIPIYGRFGYLLTEIAERYGANVHMLECEWGTVFDP 125

Query: 132 EDLDEALKK-NPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIK 190
           ED+   +KK  P +  V + + ETSTG ++PL  + +  +  D L  VDAV+ +GG ++K
Sbjct: 126 EDIIREIKKVKPKI--VAMVHGETSTGRIHPLKAIGEACRTEDALFIVDAVATIGGCEVK 183

Query: 191 FDKWELDVVFSSSQKAFGVPPGLAIGAFSERFIEI--AEKMPERGW-------------- 234
            D+W++D     +QK   VP G+A   ++ER  ++  A K  ERG               
Sbjct: 184 VDEWKIDAAIGGTQKCLSVPSGMAPITYNERVADVIAARKKVERGIATQADRAALSGNRP 243

Query: 235 ----YFDIPLYIKYLKEKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMV 290
               YFD+     Y  E+     T     ++ L   +R++ +  G E   E +      +
Sbjct: 244 ITSNYFDLSQLEDYWSERRLNHHTEATTMLYALREGVRLVLE-EGLETRFERHRHHEAAL 302

Query: 291 REGVKEIGLGILAEPGYESPTITAVLTPEGIKGDEVYEAMRKR-GFELAKGYGSVREKTF 349
             G+K +GL +  +   + P +T V  P GI G+ V + +  + G E+A  +G +  K +
Sbjct: 303 AAGIKAMGLRLFGDDSCKMPVVTCVEIPGGIDGESVRDMLLAQFGIEIASSFGPLAGKIW 362

Query: 350 RIGHMGY-MKFEDIQEMLDNLKEVIEELKKQKGI 382
           RIG MGY  + E++  +L  L+ V+  L+   GI
Sbjct: 363 RIGTMGYSCRKENVLFVLAGLEAVL--LRHNAGI 394


>dbj|BAB04481.1| (AP001509) aspartate transaminase [Bacillus halodurans]
           Length = 416
           
 Score =  159 bits (398), Expect = 5e-38
 Identities = 110/384 (28%), Positives = 186/384 (47%), Gaps = 25/384 (6%)

Query: 16  PKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPS 75
           P   + T GPV   P VL+ M   +       +  +  DT+E LR  L+ +      +  
Sbjct: 10  PARTIMTPGPVEVDPRVLQAMSRSILGQFDPAFTAIMNDTMEGLRRVLQTQNQWAYPIDG 69

Query: 76  SGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLD 135
           +    +EA + + +  G +VL+   G FG    E+ E  G +  ++  E G    P+ + 
Sbjct: 70  TSRAGIEAMLCSIIEPGDRVLIPSFGRFGGLLAEITERCGGEVHMIHTEWGTVFAPDTII 129

Query: 136 EALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWE 195
            A+K+  + + V + + +TSTG + PL E+    +EHD L  VDAV+ +GG D+K D W 
Sbjct: 130 AAIKET-EPKVVAMVHGDTSTGRIQPLQEIGYACREHDCLFIVDAVATVGGTDVKTDDWM 188

Query: 196 LDVVFSSSQKAFGVPPGLAIGAFSERFIEI--AEKMPERGW-----------------YF 236
           +D + + +QK   VP G+A   ++ R  EI    K  E+G                  YF
Sbjct: 189 IDGLITGTQKCLSVPSGMAPLTYNHRIEEILMERKSIEQGLVTGEQEELNHQRRIRSNYF 248

Query: 237 DIPLYIKYLKEKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKE 296
           D+    +Y         T     ++GL   LR+I + G ++++ E +    + +  G++ 
Sbjct: 249 DLSQLQEYWSPARLNHHTEATAALYGLYEGLRLILEEGLEQRF-ERHRTNERALVAGIEA 307

Query: 297 IGLGILAEPGYESPTITAVLTPEGIKGDEVYEAMRKRGF--ELAKGYGSVREKTFRIGHM 354
           +GL +  +PG + PT+T V  PEGI G+ V  AM    F  E+A  +G +  K +RIG M
Sbjct: 308 MGLTLFGDPGCKLPTVTCVEIPEGINGETV-RAMLLEDFAIEVASSFGPLHGKIWRIGTM 366

Query: 355 GY-MKFEDIQEMLDNLKEVIEELK 377
           GY  + +++ + L  L+ V+  L+
Sbjct: 367 GYSCQKKNVLQTLAALEAVLLRLQ 390


>sp|O08374|SGAA_HYPME SERINE--GLYOXYLATE AMINOTRANSFERASE (SGAT)
           >gi|2081618|dbj|BAA19919.1| (D86125) serine-glyoxylate
           aminotransferase [Hyphomicrobium methylovorum]
           Length = 405
           
 Score =  156 bits (391), Expect = 3e-37
 Identities = 117/372 (31%), Positives = 181/372 (48%), Gaps = 14/372 (3%)

Query: 20  LFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPSSGTG 79
           LF  GP      V   M + M   RS E+ K  +   E L+   ++K G V + PSSGTG
Sbjct: 7   LFIPGPTNIPDAVRMAMNIPMEDMRSPEFPKFTLPLFEDLKKAFKMKDGRVFIFPSSGTG 66

Query: 80  IMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLDEAL- 138
             E+++ N +  G KVL++  G F   + ++ E  G K  V + E G  V  E   + L 
Sbjct: 67  AWESAVENTLATGDKVLMSRFGQFSLLWVDMCERLGLKVEVCDEEWGTGVPVEKYADILA 126

Query: 139 -KKNPDVEAVTITYNETSTGVLNPLPELAKV--AKEHDKLVFVDAVSAMGGADIKFDKWE 195
             KN +++AV +T+NET+TGV + +  + K   A +H  L+ VD VS++G  D++  +W 
Sbjct: 127 KDKNHEIKAVFVTHNETATGVSSDVAGVRKALDAAKHPALLMVDGVSSVGSLDMRMGEWG 186

Query: 196 LDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPER--GWYFDIPLYIKYLKEKESTPS 253
           +D   S SQK F +P GL I A S++ ++I +    R    +F     IK   ++   P 
Sbjct: 187 VDCCVSGSQKGFMLPTGLGILAVSQKALDINKSKNGRMNRCFFSFEDMIK-TNDQGFFPY 245

Query: 254 TPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILA-EPGYESPTI 312
           TP    + GL   L ++    G +     + + A  VR  V   GL + A EP + S T+
Sbjct: 246 TPATQLLRGLRTSLDLL-FAEGLDNVFARHTRLASGVRAAVDAWGLKLCAKEPKWYSDTV 304

Query: 313 TAVLTPEGIKGDEVYE-AMRKRGFELAKGYGSVREKTFRIGHMGYMKFEDIQEMLDNLKE 371
           +A+L PEGI  + + + A  +       G   V  K FRIGH+G +     + M+     
Sbjct: 305 SAILVPEGIDSNAITKTAYYRYNTSFGLGLNKVAGKVFRIGHLGMLD----EVMIGGALF 360

Query: 372 VIEELKKQKGIN 383
             E   K  G+N
Sbjct: 361 AAEMALKDNGVN 372


>pir||G70437 soluble hydrogenase small subunit - Aquifex aeolicus
           >gi|2983931|gb|AAC07480.1| (AE000746) soluble
           hydrogenase small subunit [Aquifex aeolicus]
           Length = 216
           
 Score =  153 bits (383), Expect = 3e-36
 Identities = 76/197 (38%), Positives = 124/197 (62%)

Query: 19  KLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPSSGT 78
           ++FT GPV     + E++  Q+  HR+KE+ +  ++T E  +  ++      +   SSGT
Sbjct: 10  RVFTPGPVEIPDRIREVLGRQIIHHRTKEFTEAFLETRELFKRLVDCTSENFVFFASSGT 69

Query: 79  GIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLDEAL 138
           G MEAS++N    G KVL  + G FG+R+ E+  T G + V L+ E GK+V P+ +++ L
Sbjct: 70  GAMEASVQNFFNPGEKVLAVVGGKFGERWAELGRTWGLEVVELQVEWGKSVDPDQVEDIL 129

Query: 139 KKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWELDV 198
            KNP+++ V +  +E+STG  + +  LAK+ K+ D L+ VDA++A+G  ++K  +W LDV
Sbjct: 130 NKNPEIKGVLVQMSESSTGAYHDVKTLAKITKDRDTLLVVDAITALGVYNMKPHEWGLDV 189

Query: 199 VFSSSQKAFGVPPGLAI 215
           V   SQKAF +PPGL++
Sbjct: 190 VVGGSQKAFMLPPGLSM 206


>gb|AAK41188.1| Soluble hydrogenase, small subunit [Sulfolobus solfataricus]
           Length = 373
           
 Score =  149 bits (373), Expect = 4e-35
 Identities = 101/357 (28%), Positives = 185/357 (51%), Gaps = 17/357 (4%)

Query: 24  GPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGE--VLLVPSSGTGIM 81
           GPV     VL+   + + +HRS+++R    +TV+ L   +    G   V L+  SGT  +
Sbjct: 6   GPVNVPYSVLQA-SLNLVNHRSEKFR----ETVKTLEFLMNKHFGSTRVALLSGSGTLAV 60

Query: 82  EASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLDEALKKN 141
           E+ + + V +  KV+    G FG R +E +   G K +  + + G++   E++ +A+++N
Sbjct: 61  ESMVYSLVKREEKVITFPYGEFGHRLEESLIRRGAKVISYQKKLGESFTVEEIKKAIEEN 120

Query: 142 PDVEAVTITYNETSTGV-LNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWELDVVF 200
            D   V + +NETSTG+    L ++A V K     + VD+VS      +  ++W++D V 
Sbjct: 121 KDATTVALVHNETSTGIAFRDLKKIADVVKGVGLKLLVDSVSGFAAYPLYVNQWKIDCVV 180

Query: 201 SSSQKAFGVPPGLAIGAFSERFIE--IAEKMPERGWYFDIPLYIKYLKEKESTPSTPPMP 258
           + SQKA    PG+   A SE  +   +   +P    Y D+  ++K+ ++K  TP TP + 
Sbjct: 181 TGSQKALASIPGVGFAALSEEGVNELVESDLPS---YLDLSFHLKF-QDKGETPFTPTVG 236

Query: 259 QVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAEPGYESPTITAVLTP 318
             F       +++K G + +W + +E  A+ +RE + E+G  +L      S T+ A   P
Sbjct: 237 AFFASRRAAELLDKEGIENRW-KRHEACARYLREVMLEMGFKLLGNDTNFSNTVVAAFPP 295

Query: 319 EGIKGDEVYEAMRKRGFELAKGYGSVREKTFRIGHMGYMKFEDIQEMLDNLKEVIEE 375
             I  D     ++KR  E++KG G +R+K  RIG +G +    I+ ++ ++ E++++
Sbjct: 296 --IPLDTFMSELKKRNIEISKGMGELRDKIVRIGILGVVDDRAIRRLVGSMGEILKK 350


>gb|AAG20505.1| (AE005122) aspartate aminotransferase; AspC1 [Halobacterium sp.
           NRC-1]
           Length = 391
           
 Score =  145 bits (361), Expect = 1e-33
 Identities = 106/380 (27%), Positives = 182/380 (47%), Gaps = 25/380 (6%)

Query: 14  VKPKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKK------ 67
           ++  + L   GPV    EV E M   M SHRS  +  V+    E +    E         
Sbjct: 1   MREDFLLLNPGPVPVAREVREAMSAPMVSHRSAAFEAVYERAQEHVEYVFEGSTPSGDTT 60

Query: 68  ---GEVLLVPSSGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYE 124
              G  LL+  + T  MEA++ N V  GG+V+  + G FG+R+  V E       V   +
Sbjct: 61  SAGGTALLLNGTATMGMEAAVGNLVGDGGEVVAVVNGKFGRRFARVAERYADVTRVTA-D 119

Query: 125 PGKAVKPEDLDEALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAM 184
            G  V  + + +A+    DV  VT+ +NETSTG+LNP+  +  +A + D    VD V+++
Sbjct: 120 WGAPVDLDAVADAVTTETDV--VTMVHNETSTGLLNPVDAVGDIAADADARYVVDGVTSI 177

Query: 185 GGADIKFDKWELDVVFSSSQKAFGVPPGLAIGAFSERFIEI--AEKMPERGWYFDIPLYI 242
           GG + + D W +D+  + +QKA   PPGL+    ++  +     E  P   +Y DI  ++
Sbjct: 178 GGDEFRIDDWGVDIAVTDAQKALAAPPGLSAVYVTDDVVPALDGEAAP---FYEDIEWHL 234

Query: 243 KYLKEKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGI- 301
           +   E   TP T  +P   GL      I + G  ++ +  + ++A   R+G  E+GL   
Sbjct: 235 R-KAESNQTPFTSAVPLFRGLAAAAARIREEGMADR-IARHRRQAAAFRDGFHEMGLASF 292

Query: 302 --LAEPGYESPTITAVLTPEGIKGDEV---YEAMRKRGFELAKGYGSVREKTFRIGHMGY 356
             L +    S T+TA+  P G +G +     +A+  RG  ++ G G +  + FR+ +MG 
Sbjct: 293 PELNDAAAYSNTLTAIRLPAGARGADAAAFMDAVTARGVSISGGQGHLGGEIFRVSNMGQ 352

Query: 357 MKFEDIQEMLDNLKEVIEEL 376
           +  + +   +  + + ++E+
Sbjct: 353 LTAQQVVRGVRTVGDALDEV 372


>sp|P55819|SGAA_METEX SERINE--GLYOXYLATE AMINOTRANSFERASE (SGAT)
           Length = 379
           
 Score =  144 bits (360), Expect = 1e-33
 Identities = 105/347 (30%), Positives = 164/347 (47%), Gaps = 31/347 (8%)

Query: 20  LFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPSSGTG 79
           LF  GP      V+  M VQ   HRS ++  +     E  +      +G + L P+SGTG
Sbjct: 7   LFVPGPTNIPDRVMRAMMVQSEDHRSVDFPSLTKPLFEDTKKVFGSTEGTIFLFPASGTG 66

Query: 80  IMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLDEALK 139
           I E+++ N + +G KVL    G F   + ++ +  G   VV E E G   KPE ++EAL+
Sbjct: 67  IWESALSNTLARGDKVLAARFGQFSHLWIDMAQRLGLDVVVQEEEWGTGAKPEKIEEALR 126

Query: 140 --KNPDVEAVTITYNETSTGVLNPLPELAKV--AKEHDKLVFVDAVSAMGGADIKFDKWE 195
             KN +++AV + +NET+TGV + +  + K   A  H  L+FVD   A            
Sbjct: 127 ADKNHEIKAVMVVHNETATGVTSNIGAVRKAIDAAGHPALLFVDCAIA------------ 174

Query: 196 LDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPLYIKYLKEKESTPS-- 253
                  SQK   +P GL +   S++ ++ AE    R       +Y  +  +K+  P+  
Sbjct: 175 ------GSQKGLMLPAGLGVICVSQKALKAAEGQSGRNDRL-ARVYFDWEDQKKQNPTGY 227

Query: 254 ---TPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAE-PGYES 309
              TPP+P ++GL   L  + +  G E     +    +  R+ V   GL   A+ P + S
Sbjct: 228 FPYTPPLPLLYGLREALACLFE-EGLENVYHRHAVLGEATRQAVAAWGLKTCAKSPEWNS 286

Query: 310 PTITAVLTPEGIKGDEVYE-AMRKRGFELAKGYGSVREKTFRIGHMG 355
            T+TA+L PEG+   ++ + A  +    L  G   V  K FRIGH+G
Sbjct: 287 DTVTAILAPEGVDAAKIIKHAYVRYNLALGAGLSQVAGKVFRIGHVG 333


>emb|CAC17015.1| (AJ278065) putative alanine:glyoxylate aminotransferase [Xenopus
           laevis]
           Length = 415
           
 Score =  143 bits (358), Expect = 2e-33
 Identities = 100/373 (26%), Positives = 180/373 (47%), Gaps = 10/373 (2%)

Query: 16  PKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPS 75
           P+  +   GP    P +     +Q+  H   E  ++  D  + ++   + K      V  
Sbjct: 44  PQRLMLGPGPSNVPPRIQAAGGLQLIGHMHPEMFQIMDDIKQGIQYAFQTKNNLTFAVSG 103

Query: 76  SGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLD 135
           SG   ME +I N V KG  VLV + G +G+R  ++ E  G     +    G+A   +D++
Sbjct: 104 SGHCAMETAIFNVVEKGDVVLVAVKGIWGERAGDIAERIGADVRYVSKPVGEAFTLKDVE 163

Query: 136 EALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWE 195
           +AL ++       IT+ E+S+GV+ PL  L  +   ++ L+ VD+V+++GGA I  DK  
Sbjct: 164 KALAEHKP-SLFFITHGESSSGVVQPLDGLGDLCHRYNCLLLVDSVASLGGAPIYMDKQG 222

Query: 196 LDVVFSSSQKAFGVPPGLAIGAFSERFIE--IAEKMPERGWYFDIPLYIKYL---KEKES 250
           +D+++S SQK    PPG A  +FSE   +     K      Y DI     Y     +   
Sbjct: 223 IDILYSGSQKVLNAPPGTAPISFSEAASKKMFGRKTKPPSLYVDINWLANYWGCDGKPRI 282

Query: 251 TPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGI-LAEPGYES 309
              T P+   F L   L I+ ++G +  W  ++++ A  + +G++ +G+ + + +P    
Sbjct: 283 YHHTGPVTNFFTLREGLAILAELGLERSW-AVHQENALKLHKGLEALGIKLFVKDPALRL 341

Query: 310 PTITAVLTPEGIKGDEVYE-AMRKRGFELAKGYGSVREKTFRIGHMGYMKFE-DIQEMLD 367
           PT+T +  P G +  ++    M+    E+  G G    K  RIG MGY   + ++  +L+
Sbjct: 342 PTVTTISVPNGYEWKDITTFIMKNHAIEITGGLGPSTGKVLRIGLMGYNSTQLNVDRVLE 401

Query: 368 NLKEVIEELKKQK 380
            L++ +++  K+K
Sbjct: 402 ALRDALQQCPKKK 414


>gb|AAB95218.1| (AF039000) putative serine-glyoxylate aminotransferase [Fritillaria
           agrestis]
           Length = 401
           
 Score =  142 bits (355), Expect = 6e-33
 Identities = 98/363 (26%), Positives = 174/363 (46%), Gaps = 7/363 (1%)

Query: 20  LFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPSSGTG 79
           LF  GPV     V+  M      +R+     +    +E ++   +   G   ++P++GTG
Sbjct: 12  LFVPGPVNIPEPVIRAMNRNNEDYRAPAIPALTKTLLEDVKKLFKTTTGTPFIIPTTGTG 71

Query: 80  IMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLDEALK 139
             E+++ N ++ G  ++  +IG F   + +  +    K  V+E E G+    ++L   L 
Sbjct: 72  AWESALTNTLSPGDTIVSFLIGQFSLLWIDQQQRLKFKVDVIESEWGQGANLDELASKLA 131

Query: 140 --KNPDVEAVTITYNETSTGVLNPLPELAKVAKE--HDKLVFVDAVSAMGGADIKFDKWE 195
             +   ++AV I +NET+TGV N L  + K+  +  H  L+ VD VS++   D + D+W 
Sbjct: 132 ADRTHTIKAVCIVHNETATGVTNNLAAVRKLLDDYNHPALLLVDGVSSICALDFRMDEWG 191

Query: 196 LDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPLYIKYLKEKESTPSTP 255
           +DV  + SQKA  +P G+     S + +E ++       +FD   Y+K+ K     P TP
Sbjct: 192 IDVALTGSQKALSMPTGMGFICASPKALEASKTAQSARVFFDWNDYLKFYKIGTYWPYTP 251

Query: 256 PMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGL-GILAEPGYESPTITA 314
            +  ++GL   L +I +  G +  +  + +  K  R  V+  GL     +  + S T+TA
Sbjct: 252 SIQMLYGLRAALDLIFE-EGLDNVIARHSRLGKATRLAVEAWGLKNCTQKEEWHSDTVTA 310

Query: 315 VLTPEGIKGDE-VYEAMRKRGFELAKGYGSVREKTFRIGHMGYMKFEDIQEMLDNLKEVI 373
           V+ P  I   E V  A ++    L  G   V  K FRIGH+G +    +   L  ++ V+
Sbjct: 311 VVVPPYIDSSEIVRRAWKRYNLSLGLGLNKVAGKVFRIGHLGNLNELQLLGCLSGVEMVL 370

Query: 374 EEL 376
           +++
Sbjct: 371 KDV 373


>gb|AAK42719.1| Serine-pyruvate aminotransferase (agxT) [Sulfolobus solfataricus]
           Length = 384
           
 Score =  140 bits (350), Expect = 2e-32
 Identities = 105/368 (28%), Positives = 184/368 (49%), Gaps = 20/368 (5%)

Query: 20  LFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKG-EVLLVPSSGT 78
           L   GP     +VL           SKE+ +    +++ LR  +   K  + L++P  GT
Sbjct: 5   LLHVGPTTIKEDVLVAGLENNVGFTSKEFVEALAYSLKGLRYVMGASKNYQPLIIPGGGT 64

Query: 79  GIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLDEAL 138
             ME S+ + +    K+LV   G FG R++++ +       VL   PG  VKP +++E +
Sbjct: 65  SAME-SVTSLLKPNDKILVVSNGVFGDRWEQIFKRYPVNVKVLRPSPGDYVKPGEVEEEV 123

Query: 139 KKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWELDV 198
           +K+ + + V +T+ ETSTGV  P+ ++    +++ +L+ VD VS++G  ++K ++W +DV
Sbjct: 124 RKS-EYKLVALTHVETSTGVREPVKDVINKIRKYVELIVVDGVSSVGAEEVKAEEWNVDV 182

Query: 199 VFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPE-RGWYFDIPLYIKYLKEKESTP----S 253
             ++SQKA G   GL +   S + + I +      G+Y D+  ++  ++  E       +
Sbjct: 183 YLTASQKALGSAAGLGLLLLSPKALSILDSQNSIAGYYLDLRNWLPVMRGAEEGKAAYFA 242

Query: 254 TPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILA-EPGYESPTI 312
           TPP+  +  L    R+IEK  G E  ++ +   A  +R G++ +GL I+A  P   S T+
Sbjct: 243 TPPVHVILQLAEAFRLIEK-EGIENRIKRHTMVASAIRAGLEALGLEIVARRPESYSNTV 301

Query: 313 TAVL----TPEGIKGDEVYEAMRKRGFELAKGYGSVREKTFRIGHMGYMKFEDIQEMLDN 368
           T V+     P+ +    V E     G E A G      K FRIGHMG++   D    +  
Sbjct: 302 TGVILKVADPQKVLAGTVNE-----GVEFAPGVHPA-FKYFRIGHMGWVTPNDAIIAISV 355

Query: 369 LKEVIEEL 376
           ++  + +L
Sbjct: 356 IERTLRKL 363


>gb|AAC26854.1| (AF063901) alanine:glyoxylate aminotransferase; transaminase
           [Arabidopsis thaliana]
           >gi|4733989|gb|AAD28669.1|AC007209_5 (AC007209)
           alanine-glyoxylate aminotransferase [Arabidopsis
           thaliana]
           Length = 401
           
 Score =  140 bits (350), Expect = 2e-32
 Identities = 99/366 (27%), Positives = 175/366 (47%), Gaps = 7/366 (1%)

Query: 17  KYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPSS 76
           ++ LF  GPV     V+  M      +RS     +    +E ++   +   G   L P++
Sbjct: 9   RHHLFVPGPVNIPEPVIRAMNRNNEDYRSPAIPALTKTLLEDVKKIFKTTSGTPFLFPTT 68

Query: 77  GTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLDE 136
           GTG  E+++ N ++ G +++  +IG F   + +  +       V+E + G+    + L  
Sbjct: 69  GTGAWESALTNTLSPGDRIVSFLIGQFSLLWIDQQKRLNFNVDVVESDWGQGANLQVLAS 128

Query: 137 ALKK--NPDVEAVTITYNETSTGVLNPLPELAKVAK--EHDKLVFVDAVSAMGGADIKFD 192
            L +  N  ++A+ I +NET+TGV N +  +  +    +H  L+ VD VS++   D + D
Sbjct: 129 KLSQDENHTIKAICIVHNETATGVTNDISAVRTLLDHYKHPALLLVDGVSSICALDFRMD 188

Query: 193 KWELDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPLYIKYLKEKESTP 252
           +W +DV  + SQKA  +P GL I   S + +E  +       +FD   Y+K+ K     P
Sbjct: 189 EWGVDVALTGSQKALSLPTGLGIVCASPKALEATKTSKSLKVFFDWNDYLKFYKLGTYWP 248

Query: 253 STPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGL-GILAEPGYESPT 311
            TP +  ++GL   L +I +  G E  +  + +  K  R  V+  GL     +  + S T
Sbjct: 249 YTPSIQLLYGLRAALDLIFE-EGLENIIARHARLGKATRLAVEAWGLKNCTQKEEWISNT 307

Query: 312 ITAVLTPEGIKGDE-VYEAMRKRGFELAKGYGSVREKTFRIGHMGYMKFEDIQEMLDNLK 370
           +TAV+ P  I G E V  A ++    L  G   V  K FRIGH+G +    +   L  ++
Sbjct: 308 VTAVMVPPHIDGSEIVRRAWQRYNLSLGLGLNKVAGKVFRIGHLGNVNELQLLGCLAGVE 367

Query: 371 EVIEEL 376
            +++++
Sbjct: 368 MILKDV 373


>emb|CAC12147.1| (AL445066) serine-glyoxylate aminotransferase related protein
           [Thermoplasma acidophilum]
           Length = 382
           
 Score =  140 bits (350), Expect = 2e-32
 Identities = 100/315 (31%), Positives = 164/315 (51%), Gaps = 18/315 (5%)

Query: 72  LVPSSGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKP 131
           ++P SGT  ME ++ + + +G K L+   G FG R+  ++  +G +  VL  +PG AV  
Sbjct: 58  ILPGSGTVAME-TVTSLIPRGSKTLLLTNGVFGDRWIPILTAHGLQMDVLSADPGHAVSM 116

Query: 132 EDLDEALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKF 191
            D++E L+   D + + +T+ ETSTGV   +  ++K+A++H + + VD V+++G      
Sbjct: 117 ADIEEKLEGG-DYQNLIMTHVETSTGVRMDIEGVSKIARKHVERIIVDGVASLGAEREDI 175

Query: 192 DKWELDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPLYI----KYLKE 247
            +  +  + S+SQKA G PPG A+   S   +   E + E  ++F++  +I    +YL+ 
Sbjct: 176 ARLGITAIISASQKALGAPPGAALIVASRSAL---EDINEFSYFFNLKNWITPMERYLEG 232

Query: 248 KESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAEPGY 307
           K    ST P+  +  LN V   I +  G E  ++ + + +  + EG++  GL +LAE   
Sbjct: 233 KNGYLSTEPVGVILSLNRVFSDI-RTTGLEARIDDHRRLSLALNEGIEAAGLKVLAERDL 291

Query: 308 ESPTITAVLTPEGIKGDEVYEAMRKRGFELAKG-YGSVREKTFRIGHMGYMKFEDIQEML 366
            S T+TAVL+      DE+       G E A G +  +  K FRIGHMGY+   D    L
Sbjct: 292 WSNTVTAVLSDH---ADEIVRRSMDLGIEFATGVHPKLLGKYFRIGHMGYVNDFDALSAL 348

Query: 367 DNLKEVIEELKKQKG 381
                VIE    Q G
Sbjct: 349 ----SVIERAAAQSG 359


>sp|O25436|Y736_HELPY PUTATIVE AMINOTRANSFERASE HP0736 >gi|7434100|pir||H64611 probable
           transaminase (EC 2.6.1.-) HP0736 [similarity] -
           Helicobacter pylori (strain 26695)
           >gi|2313858|gb|AAD07782.1| (AE000586) phosphoserine
           aminotransferase (serC) [Helicobacter pylori 26695]
           Length = 369
           
 Score =  137 bits (341), Expect = 2e-31
 Identities = 104/359 (28%), Positives = 181/359 (49%), Gaps = 14/359 (3%)

Query: 20  LFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPSSGTG 79
           LFT GPVA   E+       M  HR+K++ K+     E L+    ++  EVLL+ SSGTG
Sbjct: 3   LFTPGPVAINEEMRTSFSQPMPHHRTKDFEKIFQSVRENLKKMTGLE--EVLLLSSSGTG 60

Query: 80  IMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLDEALK 139
            MEAS+ +   K  ++L    G FG+R+ ++ + +  KA  L YE     + +++   LK
Sbjct: 61  AMEASVISLCQK--ELLFVNAGKFGERFGKIAKAHSIKAHELVYEWDTPAQVDEILSVLK 118

Query: 140 KNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVF--VDAVSAMGGADIKFDKWELD 197
            NP+++A  I   E+S G+ +P+ ++A+  KE +  VF  VDA++A+G   ++     +D
Sbjct: 119 ANPNIDAFCIQACESSGGLRHPVEKIAQAIKETNPNVFVIVDAITALGVEPLEIT--HVD 176

Query: 198 VVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPLYIKYLKEKESTPSTPPM 257
            +   SQKAF +PP +++ A S+  IE  E+    G+YF++   +K  +   +T  T P+
Sbjct: 177 ALIGGSQKAFMLPPAMSLVALSQNAIERIEER-NVGFYFNLKSELKN-QRNNTTSYTAPI 234

Query: 258 PQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAEPGYESPTITAVLT 317
               GL     +++ +GG E      +K A   ++ V  +GL I   P   S ++T ++ 
Sbjct: 235 LHTLGLQRYFELVQNLGGFEALYRETKKAALATQKAVLALGLKIF--PKSPSLSMTTIVN 292

Query: 318 PEGIKGDEVYEAMRKRGFELAKGYGSVREKTFRIGHMGYMKFEDIQEMLDNLKEVIEEL 376
               +   + +   K   + A G    ++   RI HMG +        L+ L+  + +L
Sbjct: 293 EHAKELRNLLK--EKYQVQFAGGQEPYKDALIRINHMGIIPVYKSAYALNALELALNDL 349


>sp|Q9ZLA7|Y736_HELPJ PUTATIVE AMINOTRANSFERASE HP0736 >gi|7434101|pir||G71902 probable
           transaminase (EC 2.6.1.-) jhp0673 [similarity] -
           Helicobacter pylori (strain J99)
           >gi|4155235|gb|AAD06257.1| (AE001499) putative
           aminotransferase [Helicobacter pylori J99]
           Length = 369
           
 Score =  136 bits (340), Expect = 3e-31
 Identities = 104/359 (28%), Positives = 184/359 (50%), Gaps = 14/359 (3%)

Query: 20  LFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPSSGTG 79
           LFT GPVA   E+       M  HR+K++ K+     E L+    ++  EVLL+ SSGTG
Sbjct: 3   LFTPGPVAINEEMRSSFSQPMPHHRTKDFEKIFQSVRENLKKMTGLE--EVLLLSSSGTG 60

Query: 80  IMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLDEALK 139
            MEAS+ +   K  ++L    G FG+R+ ++ + +  KA  L YE     + + +  ALK
Sbjct: 61  AMEASVISLCQK--ELLFVNAGKFGERFGKIAKAHSIKAHELVYEWDTPAQVDGILNALK 118

Query: 140 KNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVF--VDAVSAMGGADIKFDKWELD 197
            NP+++A  I   E+S G+ +P+ ++A+  KE +  VF  VDA++A+G   ++     +D
Sbjct: 119 ANPNIDAFCIQACESSGGLRHPVEKIAQAIKETNPNVFVIVDAITALGVEPLEIT--HVD 176

Query: 198 VVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPLYIKYLKEKESTPSTPPM 257
            +   SQKAF +PP +++ A S++ I+  E+    G+YF++   +K  K   +T  T P+
Sbjct: 177 ALIGGSQKAFMLPPAMSLIALSQKAIDRIEER-NVGFYFNLKSELKNQK-NNTTSYTAPI 234

Query: 258 PQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAEPGYESPTITAVLT 317
               GL     +++ +GG E   +  ++ A   ++ V  +GL I   P   S ++T +++
Sbjct: 235 LHTLGLQRYFELVQNLGGFEALYQETKRVALASQKAVLALGLKIF--PKSPSLSMTTIVS 292

Query: 318 PEGIKGDEVYEAMRKRGFELAKGYGSVREKTFRIGHMGYMKFEDIQEMLDNLKEVIEEL 376
               +   + +   K   + A G    ++   RI HMG +        L+ L+  + +L
Sbjct: 293 EHAKELKNLLK--EKYQVQFAGGQEPYKDTLIRINHMGIIPVYKSAYALNALELALNDL 349


>pir||T24910 probable alanine--glyoxylate transaminase (EC 2.6.1.44) T14D7.1
           [similarity] - Caenorhabditis elegans
           >gi|5824614|emb|CAB03364.2| (Z81123) contains similarity
           to Pfam domain: PF00266 (Aminotransferases class-V),
           Score=126.2, E-value=2e-34, N=1~cDNA EST EMBL:Z14839
           comes from this gene~cDNA EST yk629b11.3 comes from this
           gene~cDNA EST yk629b11.5 comes from this gene
           [Caenorhabditi>
           Length = 405
           
 Score =  136 bits (340), Expect = 3e-31
 Identities = 104/366 (28%), Positives = 171/366 (46%), Gaps = 14/366 (3%)

Query: 12  EMVKPKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVL 71
           +MV P  +LF  GP      + E     +  H   E+ ++  D    L+   +       
Sbjct: 34  DMVVPPRQLFGPGPSNMADSIAETQSRNLLGHLHPEFVQIMADVRLGLQYVFKTDNKYTF 93

Query: 72  LVPSSGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKP 131
            V  +G   ME ++ N +  G K LV  IG +G+R  ++    G +   +    G+AV  
Sbjct: 94  AVSGTGHSGMECAMVNLLEPGDKFLVVEIGLWGQRAADLANRMGIEVKKITAPQGQAVPV 153

Query: 132 EDLDEALKK-NPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIK 190
           ED+ +A+    P++  V +   ++STGV  PL  +    +EH  L  VD V+++GG    
Sbjct: 154 EDIRKAIADYKPNL--VFVCQGDSSTGVAQPLETIGDACREHGALFLVDTVASLGGTPFA 211

Query: 191 FDKWELDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPER--GWYFD---IPLYIKYL 245
            D  ++D V+S++QK    PPGLA  +FS+R +E      +R   +YFD   +  Y    
Sbjct: 212 ADDLKVDCVYSATQKVLNAPPGLAPISFSDRAMEKIRNRKQRVASFYFDAIELGNYWGCD 271

Query: 246 KEKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGL-GILAE 304
            E +    T P+  V+ L   L  I K G  E  ++ ++  A+++   +K+ GL   + +
Sbjct: 272 GELKRYHHTAPISTVYALRAALSAIAKEGIDES-IQRHKDNAQVLYATLKKHGLEPFVVD 330

Query: 305 PGYESPTITAVLTPEGIKGDEVYEAMRKRGFELAKGYGSVREKTFRIGHMGY----MKFE 360
                P +T V  PEG+   +V   M   G E+A G G+   K +RIG  G      K E
Sbjct: 331 EKLRLPCLTTVKVPEGVDWKDVAGKMMTNGTEIAGGLGATVGKIWRIGTFGINSNSTKIE 390

Query: 361 DIQEML 366
           ++ E+L
Sbjct: 391 NVVELL 396


>sp|P09139|SPYA_RAT SERINE--PYRUVATE AMINOTRANSFERASE, MITOCHONDRIAL PRECURSOR (SPT)
           (ALANINE--GLYOXYLATE AMINOTRANSFERASE) (AGT)
           >gi|66655|pir||XNRTSP serine--pyruvate transaminase (EC
           2.6.1.51) precursor, mitochondrial - rat
           >gi|57747|emb|CAA29656.1| (X06357) serine pyruvate
           aminotransferase precursor (AA -22 to 392) [Rattus
           rattus] >gi|207033|gb|AAA42168.1| (M35270) peroxisomal
           serine:pyruvate aminotransferase precursor (EC 2.6.1.51;
           pSPT) [Rattus norvegicus]
           Length = 414
           
 Score =  136 bits (339), Expect = 4e-31
 Identities = 101/373 (27%), Positives = 178/373 (47%), Gaps = 10/373 (2%)

Query: 16  PKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPS 75
           PK  L   GP    P VL    ++M  H  KE  ++  +  + ++   + +    L+V  
Sbjct: 43  PKRLLLGPGPSNLAPRVLAAGSLRMIGHMQKEMFQIMDEIKQGIQYVFQTRNPLTLVVSG 102

Query: 76  SGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLD 135
           SG   ME ++ N +  G   LV   G +G R  E+ E  G +   +  +PG+    ++++
Sbjct: 103 SGHCAMETALFNLLEPGDSFLVGTNGIWGIRAAEIAERIGARVHQMIKKPGEHYTLQEVE 162

Query: 136 EALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWE 195
           E L ++  V  + +T+ E+STGVL PL    ++   +  L+ VD+V+++GG  I  D+  
Sbjct: 163 EGLAQHKPV-LLFLTHGESSTGVLQPLDGFGELCHRYQCLLLVDSVASLGGVPIYMDQQG 221

Query: 196 LDVVFSSSQKAFGVPPGLAIGAFSERFIE--IAEKMPERGWYFDIPLYIKYLKEKEST-- 251
           +D+++S SQK    PPG+++ +F+++      + K     +Y DI    K    +  T  
Sbjct: 222 IDILYSGSQKVLNAPPGISLISFNDKAKSKVYSRKTKPVSFYTDITYLSKLWGCEGKTRV 281

Query: 252 -PSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLG-ILAEPGYES 309
              T P+  ++ L   L +I + G +  W    E  A +  + ++E+GL   + +P    
Sbjct: 282 IHHTLPVISLYCLRESLALISEQGLENSWRRHREATAHL-HKCLRELGLKFFVKDPEIRL 340

Query: 310 PTITAVLTPEGIK-GDEVYEAMRKRGFELAKGYGSVREKTFRIGHMGY-MKFEDIQEMLD 367
           PTIT V  P G    D V   +     E++ G G   +K  RIG +GY    E+   + +
Sbjct: 341 PTITTVTVPAGYNWRDIVSYVLDHFNIEISGGLGPSEDKVLRIGLLGYNATTENADRVAE 400

Query: 368 NLKEVIEELKKQK 380
            L+E ++   K K
Sbjct: 401 ALREALQHCPKNK 413


>gb|AAA42169.1| (M35270) mitochondrial serine:pyruvate aminotransferase (mSPT)
           [Rattus norvegicus]
           Length = 392
           
 Score =  136 bits (339), Expect = 4e-31
 Identities = 101/373 (27%), Positives = 178/373 (47%), Gaps = 10/373 (2%)

Query: 16  PKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPS 75
           PK  L   GP    P VL    ++M  H  KE  ++  +  + ++   + +    L+V  
Sbjct: 21  PKRLLLGPGPSNLAPRVLAAGSLRMIGHMQKEMFQIMDEIKQGIQYVFQTRNPLTLVVSG 80

Query: 76  SGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLD 135
           SG   ME ++ N +  G   LV   G +G R  E+ E  G +   +  +PG+    ++++
Sbjct: 81  SGHCAMETALFNLLEPGDSFLVGTNGIWGIRAAEIAERIGARVHQMIKKPGEHYTLQEVE 140

Query: 136 EALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWE 195
           E L ++  V  + +T+ E+STGVL PL    ++   +  L+ VD+V+++GG  I  D+  
Sbjct: 141 EGLAQHKPV-LLFLTHGESSTGVLQPLDGFGELCHRYQCLLLVDSVASLGGVPIYMDQQG 199

Query: 196 LDVVFSSSQKAFGVPPGLAIGAFSERFIE--IAEKMPERGWYFDIPLYIKYLKEKEST-- 251
           +D+++S SQK    PPG+++ +F+++      + K     +Y DI    K    +  T  
Sbjct: 200 IDILYSGSQKVLNAPPGISLISFNDKAKSKVYSRKTKPVSFYTDITYLSKLWGCEGKTRV 259

Query: 252 -PSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLG-ILAEPGYES 309
              T P+  ++ L   L +I + G +  W    E  A +  + ++E+GL   + +P    
Sbjct: 260 IHHTLPVISLYCLRESLALISEQGLENSWRRHREATAHL-HKCLRELGLKFFVKDPEIRL 318

Query: 310 PTITAVLTPEGIK-GDEVYEAMRKRGFELAKGYGSVREKTFRIGHMGY-MKFEDIQEMLD 367
           PTIT V  P G    D V   +     E++ G G   +K  RIG +GY    E+   + +
Sbjct: 319 PTITTVTVPAGYNWRDIVSYVLDHFNIEISGGLGPSEDKVLRIGLLGYNATTENADRVAE 378

Query: 368 NLKEVIEELKKQK 380
            L+E ++   K K
Sbjct: 379 ALREALQHCPKNK 391


>pir||G75406 probable transaminase (EC 2.6.1.-) DR1350 [similarity] -
           Deinococcus radiodurans (strain R1)
           >gi|6459102|gb|AAF10920.1|AE001981_5 (AE001981)
           aminotransferase, class V [Deinococcus radiodurans]
           Length = 390
           
 Score =  136 bits (338), Expect = 5e-31
 Identities = 101/354 (28%), Positives = 163/354 (45%), Gaps = 16/354 (4%)

Query: 10  VYEMVKPKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVK-KG 68
           ++E    ++ L T GP    P   + +   M  H   E   ++ +    LR+    + +G
Sbjct: 2   MFEDTHDEHVLLTPGPTPIHPRAQKALIRSMLGHMDPEVFALNSEIQRDLREMYGTEPEG 61

Query: 69  EVLLVPSSGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKA 128
              L+  +G+  MEA   N V  G +VLV   G+FG+R  E+    G K  ++    G+A
Sbjct: 62  FTALLAGTGSLGMEAGFANLVEAGDEVLVCANGSFGRRMAEMAARYGAKVRLVTAPLGEA 121

Query: 129 VKPEDLDEALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGAD 188
           +KP D+  A   + D+  V + + ETSTGVLNP+PE+A++ +    L+ VDAV+  G   
Sbjct: 122 IKPADV--AAHLDDDISMVAVVHGETSTGVLNPVPEIAELVRGSGALLTVDAVTTAGMEP 179

Query: 189 IKFDKWELDVVFSSSQKAFGVPPGLAIGAFSER-FIEIAEKMPERG-WYFDIPLYIKYLK 246
               +W +D  ++ +QK    PPGLA  A SER F   A +  +   WY D      Y  
Sbjct: 180 FHMQQWGVDYAYTGAQKCLSAPPGLAPVAISERAFSRFAARRTQTPLWYCDFEGLRDYW- 238

Query: 247 EKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKM----VREGVKEIGLG-I 301
              +   T P+   F  +  LR        E+ LE  + R ++    +   +  +G    
Sbjct: 239 VNHTYHHTVPVNLHFAFHAALR-----AALEEGLEARQARVRLMGRVIERTLAPLGFSHY 293

Query: 302 LAEPGYESPTITAVLTPEGIKGDEVYEAMRKRGFELAKGYGSVREKTFRIGHMG 355
           +  P    PT+ A+  PEG     + +A+R+R   +  G G      +R+G MG
Sbjct: 294 VRRPEDRLPTVLALRLPEGFDDAGLRQALRQREISVTGGLGPTAGVIWRLGLMG 347


>sp|P31030|SPYA_RABIT SERINE--PYRUVATE AMINOTRANSFERASE (SPT) (ALANINE--GLYOXYLATE
           AMINOTRANSFERASE) (AGT) >gi|109149|pir||S24155
           alanine--glyoxylate transaminase (EC 2.6.1.44) 1 -
           rabbit >gi|164759|gb|AAA31158.1| (M84647)
           alanine:glyoxylate aminotransferase [Oryctolagus
           cuniculus]
           Length = 392
           
 Score =  135 bits (337), Expect = 7e-31
 Identities = 100/367 (27%), Positives = 178/367 (48%), Gaps = 10/367 (2%)

Query: 16  PKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPS 75
           P   L   GP    P VL    +QM  H  +E  +V  +  + ++   + +    L V  
Sbjct: 21  PHRLLLGPGPSNLPPRVLAAGGLQMIGHMHEEMYQVMDEIKQGIQYAFQTRNALTLAVSG 80

Query: 76  SGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLD 135
           SG   +E ++ N +  G   LV   G +G+R  EV E  G +   +  +PG     ++++
Sbjct: 81  SGHCALETALFNLLEPGDAFLVGANGIWGQRAAEVGERIGARVHPMIKDPGSHYTLQEVE 140

Query: 136 EALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWE 195
           E L ++  V  + +T+ E+STGVL PL    ++   +  L+ VD+V+++GGA I  D+  
Sbjct: 141 ECLAQHKPV-LLFLTHGESSTGVLQPLDGFGELCHRYKCLLLVDSVASLGGAPIYMDQQG 199

Query: 196 LDVVFSSSQKAFGVPPGLAIGAFSERFIE--IAEKMPERGWYFDIPLYIKYL---KEKES 250
           +DV++S SQKA   PPG ++ +FS++      A K     +Y D+ L         +   
Sbjct: 200 IDVLYSGSQKALNAPPGTSLISFSDKAKSKIYARKTKPFSFYMDVQLLANIWGCDGKPRM 259

Query: 251 TPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGI-LAEPGYES 309
              T P+  +F L   L ++ + G ++ W + + + A+ +   ++E+GL + + +P    
Sbjct: 260 YHHTTPVIGIFALRESLALLVEQGLEKSW-QRHREVAQHLYRRLQELGLQLFVKDPALRL 318

Query: 310 PTITAVLTPEGIK-GDEVYEAMRKRGFELAKGYGSVREKTFRIGHMG-YMKFEDIQEMLD 367
           PT+T V+ P   +  D V   M   G E+  G G   +K  RIG +G     E++  +  
Sbjct: 319 PTVTTVIVPASYRWRDIVSYVMHHFGIEITGGLGPSADKVLRIGLLGCNATRENVDRLAT 378

Query: 368 NLKEVIE 374
            L+E ++
Sbjct: 379 ALREALQ 385


>sp|P31029|SPYA_CALJA SERINE--PYRUVATE AMINOTRANSFERASE, MITOCHONDRIAL PRECURSOR (SPT)
           (ALANINE--GLYOXYLATE AMINOTRANSFERASE) (AGT)
           >gi|104970|pir||S24154 alanine--glyoxylate transaminase
           (EC 2.6.1.44) 1 precursor - common marmoset
           >gi|176612|gb|AAA35397.1| (M84414) alanine:glyoxylate
           aminotransferase [Callithrix sp.]
           Length = 414
           
 Score =  133 bits (331), Expect = 4e-30
 Identities = 94/374 (25%), Positives = 181/374 (48%), Gaps = 12/374 (3%)

Query: 16  PKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPS 75
           P   L   GP    P  +    +QM  H  KE  ++  +  E ++   + +    L++  
Sbjct: 43  PTRLLLGPGPSNLPPRTMAAGGLQMLGHMHKETYQIMDEIKEGIQYVFQTRNPLTLVISG 102

Query: 76  SGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLD 135
           SG   +EA++ N +  G   LV + G +G+R  ++ E  G +   +  +PG     ++++
Sbjct: 103 SGHCALEAALINVLEPGDSFLVGVNGIWGQRAADIGERLGARVHPMTKDPGGHYTLQEVE 162

Query: 136 EALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWE 195
           E L ++  V  + +T+ E+S+GVL PL    ++   +  L+ VD+V+++GGA +  D+  
Sbjct: 163 EGLAQHKPV-LLFLTHGESSSGVLQPLDGFGELCHRYKCLLLVDSVASLGGAPLYMDQQG 221

Query: 196 LDVVFSSSQKAFGVPPGLAIGAFSERFIE--IAEKMPERGWYFDIPLYIKYLKEKESTP- 252
           +D+++S SQK    PPG ++ +FS+       + K     +Y D+  Y+  L   +  P 
Sbjct: 222 IDILYSGSQKVLNAPPGTSLLSFSDTAKNKIYSRKTKPSSFYLDVK-YLANLWGCDGQPR 280

Query: 253 ---STPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGI-LAEPGYE 308
               T P+  ++ L   L ++ + G +  W   + + A  +   ++ +GL + + +P   
Sbjct: 281 MYHHTTPVVSLYSLREGLALLSEQGLENSW-RKHREAAAYLHGRLQALGLRLFVKDPALR 339

Query: 309 SPTITAVLTPEGIKGDEVYEAMRKR-GFELAKGYGSVREKTFRIGHMG-YMKFEDIQEML 366
            PT+T V  P G    ++   + +R G E+  G G    K  RIG MG     E++  + 
Sbjct: 340 LPTVTTVAVPTGYDWRDIVSYLIERFGIEITGGLGPSTGKVLRIGLMGCNATRENVDLVT 399

Query: 367 DNLKEVIEELKKQK 380
           + L+E ++   K+K
Sbjct: 400 EALREALQHCPKKK 413


>gb|AAF46168.1| (AE003437) Spat gene product [Drosophila melanogaster]
           Length = 394
           
 Score =  131 bits (327), Expect = 1e-29
 Identities = 103/372 (27%), Positives = 179/372 (47%), Gaps = 13/372 (3%)

Query: 16  PKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPS 75
           P   L   GP  C   VLE M   +  H   E  ++  +  E ++   +      + +  
Sbjct: 16  PSKTLMGPGPSNCSHRVLEAMSNPVLGHMHPECLQIMDEVKEGIKYIFQTLNDATMCISG 75

Query: 76  SGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLD 135
           +G   MEA++ N +  G  VL+ I G +G R  ++    G +   +E   G+A+  E++ 
Sbjct: 76  AGHSGMEAALCNLIEDGDVVLMGITGVWGHRAGDMARRYGAEVHYVEASFGRALSHEEIT 135

Query: 136 EALKKNPDVEAVTITYNETSTGVLNP-LPELAKVAKEHDKLVFVDAVSAMGGADIKFDKW 194
            A + +   +   I   ++STG++   + EL ++ +++D  + VD V+++GG +   D+W
Sbjct: 136 FAFEAHRP-KVFFIAQGDSSTGIIQQNIRELGELCRKYDCFLIVDTVASLGGTEFLMDEW 194

Query: 195 ELDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERG--WYFDIPLYIKYLKEKESTP 252
           ++DV ++ SQK+ G P GL   +FS+R +    K   +   +YFDI L  +Y      TP
Sbjct: 195 KVDVAYTGSQKSLGGPAGLTPISFSKRALTRIRKRKTKPKVYYFDILLIGQYW-GCYGTP 253

Query: 253 ----STPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAEPGYE 308
                T     ++GL   L     +G K   +  +++ +K ++ G++E+GL +      E
Sbjct: 254 RIYHHTISSTLLYGLREALAHFCAVGLKAV-VRRHQECSKRLQLGIEELGLEMFVSREEE 312

Query: 309 S-PTITAVLTPEGIKGDEVYE-AMRKRGFELAKGYGSVREKTFRIGHMG-YMKFEDIQEM 365
             PT+  +  P G+   +V E AMRK   E++ G G   E  FRIG MG     E +  +
Sbjct: 313 RLPTVNTIKVPFGVDWKKVAEYAMRKYSVEISGGLGPTVEHVFRIGLMGENATVERVDMV 372

Query: 366 LDNLKEVIEELK 377
           L  L E I+  K
Sbjct: 373 LSILNEAIQSSK 384


>gi|7709978 alanine-glyoxylate aminotransferase; alanine-glyoxylate
           aminotransferase 1 [Mus musculus]
           >gi|10720292|sp|O35423|SPYA_MOUSE SERINE--PYRUVATE
           AMINOTRANSFERASE, MITOCHONDRIAL PRECURSOR (SPT)
           (ALANINE--GLYOXYLATE AMINOTRANSFERASE) (AGT)
           >gi|6180226|gb|AAB82001.2| (AF027730) alanine:glyoxylate
           aminotransferase [Mus musculus]
           Length = 413
           
 Score =  130 bits (324), Expect = 2e-29
 Identities = 95/372 (25%), Positives = 175/372 (46%), Gaps = 9/372 (2%)

Query: 16  PKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPS 75
           P   L   GP    P VL    ++M  H  KE  ++  +  + ++   + +    L+V  
Sbjct: 43  PTRLLLGPGPSNLAPRVLAAGSLRMIGHMQKEMLQIMEEIKQGIQYVFQTRNPLTLVVSG 102

Query: 76  SGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLD 135
           SG   ME ++ N +  G   L    G +G R  E+ +  G +   +  +PG+    ++++
Sbjct: 103 SGHCAMETALFNLLEPGDSFLTGTNGIWGMRAAEIADRIGARVHQMIKKPGEHYTLQEVE 162

Query: 136 EALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWE 195
           E L ++  V  + + + E+STGV+ PL    ++   +  L+ VD+V+++GG  I  D+  
Sbjct: 163 EGLAQHKPV-LLFLVHGESSTGVVQPLDGFGELCHRYQCLLLVDSVASLGGVPIYMDQQG 221

Query: 196 LDVVFSSSQKAFGVPPGLAIGAFSE--RFIEIAEKMPERGWYFDIPLYIKYL---KEKES 250
           +D+++SSSQK    PPG+++ +F++  ++   + K     +Y DI    K      E   
Sbjct: 222 IDIMYSSSQKVLNAPPGISLISFNDKAKYKVYSRKTKPVSFYTDITYLAKLWGCEGETRV 281

Query: 251 TPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLG-ILAEPGYES 309
              T P+  ++ L   L +I + G +  W    E  A +  + ++E+GL   + +P    
Sbjct: 282 IHHTTPVTSLYCLRESLALIAERGLENCWRRHREATAHL-HKHLQEMGLKFFVKDPEIRL 340

Query: 310 PTITAVLTPEGIKGDEVYEAMRKRGFELAKGYGSVREKTFRIGHMGY-MKFEDIQEMLDN 368
           PTIT V        D V   +     E++ G G   E+  RIG +GY    E++  + + 
Sbjct: 341 PTITTVTAAGYNWRDIVSYVLDHFSIEISGGLGPTEERVLRIGLLGYNATTENVDRVAEA 400

Query: 369 LKEVIEELKKQK 380
           L+E ++   K K
Sbjct: 401 LREALQHCPKNK 412


>pir||A75451 probable soluble hydrogenase (EC 1.12.-.-) small chain DR0991
           [similarity] - Deinococcus radiodurans (strain R1)
           >gi|6458719|gb|AAF10567.1|AE001951_7 (AE001951)
           aminotransferase, class V [Deinococcus radiodurans]
           Length = 391
           
 Score =  129 bits (321), Expect = 5e-29
 Identities = 96/363 (26%), Positives = 162/363 (44%), Gaps = 10/363 (2%)

Query: 19  KLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPSSGT 78
           +L   GPV   P+VL  +      HR+ +     ++  E+L   L     + ++  SSGT
Sbjct: 22  RLIAPGPVEVAPDVLLALAQPQMHHRAPQGVAKLMEAREKLTRLLG-DPYDAVITTSSGT 80

Query: 79  GIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLDEAL 138
           G  E ++ +    G KV+    G F +R+ ++ +       ++    G+ + P+++ +A 
Sbjct: 81  GAFEGALVSTTPTGAKVVNAQAGKFSERWGDMAKRFSYDTQIVAKPWGEMLDPDEVADAC 140

Query: 139 KKNPDVEAVTITYNETSTGVLNPLPELAKVAKEH--DKLVFVDAVSAMGGADIKFDKWEL 196
           +       +TIT++ETSTG L+ L  +A  AK    D ++  D +++ G A+++   W +
Sbjct: 141 R---GAHTLTITHSETSTGALHDLEAIAGAAKAQNPDLIIIADCITSYGNAELRPAAWGV 197

Query: 197 DVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPLYIKYLKEKESTPSTPP 256
           DVV S SQK    PPGL    FS        K    G+Y D+   +   K   STP TP 
Sbjct: 198 DVVVSGSQKGTATPPGLGFVLFSPEVQGRMIKNTPHGFYLDMTRELAGQK-AGSTPQTPA 256

Query: 257 MPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAEPGYESPTITAVL 316
           +  ++ L+V L  + ++  +  W E   K   ++  G     LG  A     S  +  + 
Sbjct: 257 INLIYALSVALDHLLRVPLEVLWAEQRRKTDALIAAGT---ALGAPAWAARPSAAVAVLR 313

Query: 317 TPEGIKGDEVYEAMRKRGFELAKGYGSVREKTFRIGHMGYMKFEDIQEMLDNLKEVIEEL 376
            PEGI G +V   + + G     G     +  FR+  MGY    D   +   L++    L
Sbjct: 314 PPEGIGGKQVAARLAEMGQRALPGQAPHEDTVFRVSTMGYADRYDTLGIAGMLEDCFASL 373

Query: 377 KKQ 379
             Q
Sbjct: 374 GVQ 376


>gb|AAG26467.1|AF285774_7 (AF285774) putative 2-aminoethylphosphonate pyruvate
           aminotransferase [Bacteroides fragilis]
           Length = 366
           
 Score =  125 bits (311), Expect = 8e-28
 Identities = 94/362 (25%), Positives = 169/362 (45%), Gaps = 14/362 (3%)

Query: 20  LFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFL------EVKKGEVLLV 73
           L   GP      V     V     R KE+  +    +++LRD L      ++ K   +L 
Sbjct: 8   LLNPGPATTTDTVKLAQVVPDICPREKEFAGM----MKQLRDDLVRVAHGDLSKHTAVLF 63

Query: 74  PSSGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPED 133
             SGT  ++  + + +    KVLV   GA+  R  EV E  G   + L++   +      
Sbjct: 64  CGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSV 123

Query: 134 LDEALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDK 193
           +++ L  NPD+  V  T++ET TG+LNP+ E+ K+A  H  +  VD  S++G       K
Sbjct: 124 IEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGK 183

Query: 194 WELDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPLYIKYLKEKESTPS 253
             +D   +S+QK      GL+     E  I  +   P+R +Y ++ L   Y ++      
Sbjct: 184 DNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHF 243

Query: 254 TPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAEPGYESPTIT 313
           TPP+  V+     L     +G + K+   +++  + + +G++E+GL    +  ++S  + 
Sbjct: 244 TPPVQTVYAARQALDEYFAVGEEAKFAR-HKRVFEAIHKGLQELGLQYAIKREWQSGLVV 302

Query: 314 AVLTPEG--IKGDEVYEAMRKRGFELAKGYGSVREKTFRIGHMGYMKFEDIQEMLDNLKE 371
           +VL P+      D+V++   +RGF +  G  S    TFR+  +G +  EDI+   + ++E
Sbjct: 303 SVLYPDDPLWDFDKVHDYCYERGFTIYPGKIST-TNTFRLCALGEIDVEDIERFFEVMRE 361

Query: 372 VI 373
            +
Sbjct: 362 AV 363


>prf||1704252A Ala/glyoxylate aminotransferase [Homo sapiens]
           Length = 392
           
 Score =  124 bits (308), Expect = 2e-27
 Identities = 92/373 (24%), Positives = 176/373 (46%), Gaps = 10/373 (2%)

Query: 16  PKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPS 75
           P   L   GP    P ++    +QM    SK+  ++  +  E ++   + +    L++  
Sbjct: 21  PNQLLLGPGPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEIKEGIQYVFQTRNPLTLVISG 80

Query: 76  SGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLD 135
           SG   +EA++ N +  G   LV   G +G+R  ++ E  G +   +  +PG     ++++
Sbjct: 81  SGHCALEAALVNVLEPGDSFLVGANGIWGQRAVDIGERIGARVHPMTKDPGGHYTLQEVE 140

Query: 136 EALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWE 195
           E L ++  V  + +T+ E+STGVL PL    ++   +  L+ VD+V+++GG  +  D+  
Sbjct: 141 EGLAQHKPV-LLFLTHGESSTGVLQPLDGFRELCHRYKCLLLVDSVASLGGTPLYMDRQG 199

Query: 196 LDVVFSSSQKAFGVPPGLAIGAFSERFIE--IAEKMPERGWYFDIPLYIKYL---KEKES 250
           +D+++S SQKA   PPG ++ +FS++  +   + K     +Y DI     +     +   
Sbjct: 200 IDILYSGSQKALNAPPGTSLISFSDKAKKKMYSRKTKPFSFYLDIKWLANFWGCDDQPRM 259

Query: 251 TPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGI-LAEPGYES 309
              T P+  ++ L   L +I + G +  W   + + A  +   ++ +GL + + +P    
Sbjct: 260 YHHTIPVISLYSLRESLALIAEQGLENSW-RQHREAAAYLHGRLQALGLQLFVKDPTLRL 318

Query: 310 PTITAVLTPEGIK-GDEVYEAMRKRGFELAKGYGSVREKTFRIGHMG-YMKFEDIQEMLD 367
           PT+T V  P G    D V   M     E+  G G    K  RIG +G     E++  + +
Sbjct: 319 PTVTTVAVPAGYDWRDIVSYVMDHFDIEIMGGLGPSTGKVLRIGLLGCNATRENVDRVTE 378

Query: 368 NLKEVIEELKKQK 380
            L+  ++   K+K
Sbjct: 379 ALRAALQHCPKKK 391


>gi|4557289 alanine-glyoxylate aminotransferase; Alanine-glyoxylate
           aminotransferase, liver-specific peroxisomal [Homo
           sapiens] >gi|134855|sp|P21549|SPYA_HUMAN
           SERINE--PYRUVATE AMINOTRANSFERASE (SPT)
           (ALANINE--GLYOXYLATE AMINOTRANSFERASE) (AGT)
           >gi|66654|pir||XNHUSP serine--pyruvate transaminase (EC
           2.6.1.51), peroxisomal - human >gi|28561|emb|CAA37493.1|
           (X53414) L- alanine:glyoxylate aminotransferase [Homo
           sapiens] >gi|36582|emb|CAA39572.1| (X56092)
           serine--pyruvate  aminotransferase [Homo sapiens]
           >gi|178273|gb|AAA51680.1| (M61763) alanine:glyoxylate
           aminotransferase [Homo sapiens]
           Length = 392
           
 Score =  123 bits (307), Expect = 2e-27
 Identities = 91/373 (24%), Positives = 176/373 (46%), Gaps = 10/373 (2%)

Query: 16  PKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPS 75
           P   L   GP    P ++    +QM    SK+  ++  +  E ++   + +    L++  
Sbjct: 21  PNQLLLGPGPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEIKEGIQYVFQTRNPLTLVISG 80

Query: 76  SGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLD 135
           SG   +EA++ N +  G   LV   G +G+R  ++ E  G +   +  +PG     ++++
Sbjct: 81  SGHCALEAALVNVLEPGDSFLVGANGIWGQRAVDIGERIGARVHPMTKDPGGHYTLQEVE 140

Query: 136 EALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWE 195
           E L ++  V  + +T+ E+STGVL PL    ++   +  L+ VD+V+++GG  +  D+  
Sbjct: 141 EGLAQHKPV-LLFLTHGESSTGVLQPLDGFGELCHRYKCLLLVDSVASLGGTPLYMDRQG 199

Query: 196 LDVVFSSSQKAFGVPPGLAIGAFSERFIE--IAEKMPERGWYFDIPLYIKYL---KEKES 250
           +D+++S SQKA   PPG ++ +FS++  +   + K     +Y DI     +     +   
Sbjct: 200 IDILYSGSQKALNAPPGTSLISFSDKAKKKMYSRKTKPFSFYLDIKWLANFWGCDDQPRM 259

Query: 251 TPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGI-LAEPGYES 309
              T P+  ++ L   L +I + G +  W   + + A  +   ++ +GL + + +P    
Sbjct: 260 YHHTIPVISLYSLRESLALIAEQGLENSW-RQHREAAAYLHGRLQALGLQLFVKDPALRL 318

Query: 310 PTITAVLTPEGIK-GDEVYEAMRKRGFELAKGYGSVREKTFRIGHMG-YMKFEDIQEMLD 367
           PT+T V  P G    D V   +     E+  G G    K  RIG +G     E++  + +
Sbjct: 319 PTVTTVAVPAGYDWRDIVSYVIDHFDIEIMGGLGPSTGKVLRIGLLGCNATRENVDRVTE 378

Query: 368 NLKEVIEELKKQK 380
            L+  ++   K+K
Sbjct: 379 ALRAALQHCPKKK 391


>sp|P41689|SPYA_FELCA SERINE--PYRUVATE AMINOTRANSFERASE, MITOCHONDRIAL PRECURSOR (SPT)
           (ALANINE--GLYOXYLATE AMINOTRANSFERASE) (AGT)
           >gi|631910|pir||S43253 alanine--glyoxylate transaminase
           (EC 2.6.1.44) 1 precursor - cat
           >gi|475171|emb|CAA53527.1| (X75923) alanine--glyoxylate
           aminotransferase [Felis catus]
           Length = 414
           
 Score =  123 bits (306), Expect = 3e-27
 Identities = 98/374 (26%), Positives = 175/374 (46%), Gaps = 12/374 (3%)

Query: 16  PKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPS 75
           P   L   GP    P VL     QM  H  KE  ++  D  + ++   + K    L +  
Sbjct: 43  PNRLLLGPGPSNLAPRVLVAGGKQMIGHMHKEMFQIMDDIKQGIQYVFQTKNPLTLAISG 102

Query: 76  SGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLD 135
           SG   +EA++ N +  G   LV + G +G+R  ++ E  G +   +  +PG     ++L+
Sbjct: 103 SGHCALEAALFNILEPGDPFLVGVNGIWGQRAADIGERIGARVHPMIKDPGNHYTLQELE 162

Query: 136 EALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWE 195
           EAL ++  V  + +T  E+S+GVL PL    ++   ++ L+ VD+V+++ G  I  D+  
Sbjct: 163 EALAQHKPV-LLFLTQGESSSGVLQPLDGYGELCHRYNCLLLVDSVASLCGTPIYMDQQG 221

Query: 196 LDVVFSSSQKAFGVPPGLAIGAFSERFIE--IAEKMPERGWYFDIPLYIKYLKEKESTP- 252
           +DV++S SQK    PPG ++ +FS++        K     +Y D+  ++  +   +  P 
Sbjct: 222 IDVLYSGSQKVLNSPPGTSLISFSDKAKNKIYTRKTKPVSFYLDMK-WLANIWGCDGKPR 280

Query: 253 ---STPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGI-LAEPGYE 308
               T P+  ++ L   L +I + G +  W +  E  A  +   ++ +GL + + +P   
Sbjct: 281 IYHHTTPVVSLYSLRESLALIAEQGLENSWRQHREVTA-YLHGRLQGLGLQLFVKDPALR 339

Query: 309 SPTITAVLTPEGIK-GDEVYEAMRKRGFELAKGYGSVREKTFRIGHMG-YMKFEDIQEML 366
            PT+T V  P G    D V   M     E+  G G    K  RIG +G     E++  ++
Sbjct: 340 LPTVTTVAVPAGYDWRDIVNYVMDHFDIEITGGLGPSMGKVLRIGLLGCNATRENVDRVI 399

Query: 367 DNLKEVIEELKKQK 380
             L+E ++   + K
Sbjct: 400 QALQEALQRCSRNK 413


>dbj|BAA02632.1| (D13368) alanine:glyoxylate aminotransferase [Homo sapiens]
           Length = 392
           
 Score =  122 bits (304), Expect = 5e-27
 Identities = 91/373 (24%), Positives = 175/373 (46%), Gaps = 10/373 (2%)

Query: 16  PKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPS 75
           P   L   GP    P ++    +QM    SK+  ++  +  E ++   + +    L++  
Sbjct: 21  PNQLLLGPGPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEIKEGIQYVFQTRNPLTLVISG 80

Query: 76  SGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLD 135
           SG   +EA++ N +  G   LV   G +G+R  ++ E  G +   +  +PG     ++++
Sbjct: 81  SGHCALEAALVNVLEPGDSFLVGANGIWGQRAVDIGERIGARVHPMTKDPGGHYTLQEVE 140

Query: 136 EALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWE 195
           E L ++  V  + +T+ E+STGVL PL    ++   +  L+ VD+V+ +GG  +  D+  
Sbjct: 141 EGLAQHKPV-LLFLTHGESSTGVLQPLDGFGELCHRYKCLLLVDSVAFLGGTPLYMDRQG 199

Query: 196 LDVVFSSSQKAFGVPPGLAIGAFSERFIE--IAEKMPERGWYFDIPLYIKYL---KEKES 250
           +D+++S SQKA   PPG ++ +FS++  +   + K     +Y DI     +     +   
Sbjct: 200 IDILYSGSQKALNAPPGTSLISFSDKAKKKMYSRKTKPFSFYLDIKWLANFWGCDDQPRM 259

Query: 251 TPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGI-LAEPGYES 309
              T P+  ++ L   L +I + G +  W   + + A  +   ++ +GL + + +P    
Sbjct: 260 YHHTIPVISLYSLRESLALIAEQGLENSW-RQHREAAAYLHGRLQALGLQLFVKDPALRL 318

Query: 310 PTITAVLTPEGIK-GDEVYEAMRKRGFELAKGYGSVREKTFRIGHMG-YMKFEDIQEMLD 367
           PT+T V  P G    D V   +     E+  G G    K  RIG +G     E++  + +
Sbjct: 319 PTVTTVAVPAGYDWRDIVSYVIDHFDIEIMGGLGPSTGKVLRIGLLGCNATRENVDRVTE 378

Query: 368 NLKEVIEELKKQK 380
            L+  ++   K+K
Sbjct: 379 ALRAALQHCPKKK 391


>emb|CAA71715.1| (Y10727) alanine--glyoxylate aminotransferase [Cavia porcellus]
           Length = 392
           
 Score =  122 bits (303), Expect = 7e-27
 Identities = 98/374 (26%), Positives = 170/374 (45%), Gaps = 12/374 (3%)

Query: 16  PKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPS 75
           P   L   GP    P V     +QM  H  KE  +V  +  + ++   + +    L +  
Sbjct: 21  PNRLLLGPGPSNLAPRVQAAGGLQMIGHMHKETFQVMDEIKKGIQYVFQTRNPLTLAISG 80

Query: 76  SGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLD 135
           SG   +E ++ N +  G   LV   G +G+R  E+ E  G     +  EPG     ++++
Sbjct: 81  SGHCALEVALFNLLEPGDSFLVGANGEWGRRAAEIGERIGAHVHAMIKEPGSYYTLQEVE 140

Query: 136 EALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWE 195
           E L ++  V  + +T  E+STGVL PL    ++   +  L+ VDAV+++GG  I  D   
Sbjct: 141 EGLAQHKPV-LLFLTQGESSTGVLQPLDGYGELCHRYQCLLLVDAVASLGGVPIFMDHQG 199

Query: 196 LDVVFSSSQKAFGVPPGLAIGAFSERFIE--IAEKMPERGWYFDIPLYIKYLKEKESTP- 252
           +D ++S SQK    PPG ++ +FS+R      + K     +  DI L +  L   +  P 
Sbjct: 200 IDALYSGSQKVLNGPPGTSLLSFSDRAKHKVYSRKTKPFSFLMDITL-LANLWGCDDKPR 258

Query: 253 ---STPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGI-LAEPGYE 308
               T P+  +F L   L +I + G +  W   + +  + +   ++ +GL + + +P   
Sbjct: 259 MYHHTTPIIGLFTLRESLALISEQGLESSW-RQHREAMEHLHSRLQGLGLQLFVRDPASR 317

Query: 309 SPTITAVLTPEGIKGDEVYE-AMRKRGFELAKGYGSVREKTFRIGHMG-YMKFEDIQEML 366
            PT+T V  P G    ++ +  M     E++ G G    K  RIG MG     E++  + 
Sbjct: 318 LPTVTTVAVPAGYNWRDIVDYVMDSFSIEISGGLGPSLGKVLRIGLMGCNASRENVDRLA 377

Query: 367 DNLKEVIEELKKQK 380
             LKE ++   + +
Sbjct: 378 QALKEALQRCPRHR 391


>pir||H82437 2-aminoethylphosphonate--pyruvate aminotransferase (EC 2.6.1.-)
           VCA0604 [imported] - Vibrio cholerae (group O1 strain
           N16961) >gi|9658016|gb|AAF96505.1| (AE004391)
           2-aminoethylphosphonate:pyruvate aminotransferase
           [Vibrio cholerae]
           Length = 367
           
 Score =  120 bits (299), Expect = 2e-26
 Identities = 104/371 (28%), Positives = 178/371 (47%), Gaps = 20/371 (5%)

Query: 14  VKPKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVER-LRDFLEVKKGEV-L 71
           +K  Y L T GP++    V E M ++ +     +Y    V+ + R L      + G   +
Sbjct: 1   MKNAYLLLTPGPLSTSESVREAM-LKDWCTWDDDYNLEIVEVIRRKLVTLATTQSGYTSV 59

Query: 72  LVPSSGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKP 131
           L+  SGT  +EA+I + +    K+LV   GA+G R  ++ +       V+   PG+  +P
Sbjct: 60  LMQGSGTASVEATIGSVMLPTDKLLVIDNGAYGARIAQIAQYLNIACRVIA--PGETAQP 117

Query: 132 --EDLDEALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADI 189
             +++ + L  +P +  V I + ET+TG+LNP+ E+AK+AK+H K V +DA+S+ GG  +
Sbjct: 118 NLDEIADVLTHDPAITHVAIVHCETTTGMLNPIAEVAKIAKQHGKRVILDAMSSFGGIPM 177

Query: 190 KFDKWELDVVFSSSQKAF-GVPP-GLAIGAFSERFIEIAEKMPERGWYFDIPLYIKYL-- 245
                 +D + SS+ K   GVP  G  I   SE      E+   R     + L+ ++   
Sbjct: 178 DIGALGIDFMISSANKCIQGVPGFGFVIAKRSE-----LEQCQGRARSLTLDLFDQWQCM 232

Query: 246 -KEKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAE 304
            K       T P   V      L  +E  GG     + Y+     + +G++E+G   L  
Sbjct: 233 EKNHGKWRFTSPTHTVRAFYQALLELESEGGIAARYQRYQTNQTQLVKGMRELGFAPLLP 292

Query: 305 PGYESPTITAVLTPE--GIKGDEVYEAMRKRGFELAKGYGSVREKTFRIGHMGYMKFEDI 362
               SP IT+  +PE    +  E Y+ ++++GF +  G  S     FRIG++G +  +DI
Sbjct: 293 EKLHSPIITSFYSPEHSDYQFAEFYQRLKQQGFVIYPGKVS-HADCFRIGNIGEVYPQDI 351

Query: 363 QEMLDNLKEVI 373
           + +L  ++  I
Sbjct: 352 ERLLSAMQHAI 362


>pir||B83482 2-aminoethylphosphonate:pyruvate aminotransferase PA1310 [imported]
           - Pseudomonas aeruginosa (strain PAO1)
           >gi|9947247|gb|AAG04699.1|AE004560_7 (AE004560)
           2-aminoethylphosphonate:pyruvate aminotransferase
           [Pseudomonas aeruginosa]
           Length = 371
           
 Score =  118 bits (294), Expect = 8e-26
 Identities = 98/364 (26%), Positives = 163/364 (43%), Gaps = 12/364 (3%)

Query: 20  LFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGE----VLLVPS 75
           L T GP+         M V   S  S ++ ++     +RL   L++  GE     + +  
Sbjct: 10  LLTPGPLTTSYRTRRAMMVDWGSWDS-DFNELTASVCQRL---LKIVGGEGSHTCVPLQG 65

Query: 76  SGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLD 135
           SGT  +EA+I   V + GKVLV I GA+GKR  ++ E   R    LE E        D++
Sbjct: 66  SGTFAVEAAIGTLVPRDGKVLVLINGAYGKRLAKICEVLQRPFSTLETEENVPTTAADVE 125

Query: 136 EALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWE 195
             L  +P +  V + + ETSTG+LNPL  +AKV + H K + VDA+S+ G   I   K  
Sbjct: 126 RLLAADPAISHVALIHCETSTGILNPLEAIAKVVERHGKRLIVDAMSSFGAIGIDARKVP 185

Query: 196 LDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPLYIKYLKEKESTPSTP 255
            D + ++S K     PG+    F+      A          D+     Y+++      TP
Sbjct: 186 FDALIAASGKCLEGVPGMGF-VFARSAALEASAGNCHSLAMDLQDQHAYMRKTGQWRFTP 244

Query: 256 PMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILAEPGYESPTITAV 315
           P   V  L+  L   E+ GG       Y    + +   +  +G         ++P I   
Sbjct: 245 PTHVVAALHEALSQYEEEGGLPARQRRYASNCETLLGEMARLGFRSFLPAEIQAPIIVTF 304

Query: 316 LTPEG--IKGDEVYEAMRKRGFELAKGYGSVREKTFRIGHMGYMKFEDIQEMLDNLKEVI 373
             P     +  + Y+ +R++GF L  G    + +TFR+G +G++   ++++ +  + E +
Sbjct: 305 HAPRDPRYRFADFYQRVREKGFILYPG-KLTQVETFRVGCIGHVDAAEMRQAVAAIGEAL 363

Query: 374 EELK 377
            EL+
Sbjct: 364 RELE 367


>pir||T46947 2-aminoethylphosphonate--pyruvate aminotransferase (EC 2.6.1.-)
           phnW [imported] - Salmonella typhimurium
           >gi|1763079|gb|AAB39642.1| (U69493) PhnW [Salmonella
           typhimurium]
           Length = 367
           
 Score =  110 bits (273), Expect = 2e-23
 Identities = 96/369 (26%), Positives = 170/369 (46%), Gaps = 20/369 (5%)

Query: 13  MVKPKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEV----KKG 68
           M    Y L T GP+     V E M     +    +Y   ++  VE++R  L       +G
Sbjct: 1   MTSRNYLLLTPGPLTTSRTVKEAMLFDSCTW-DDDY---NIGVVEQIRQQLTALATASEG 56

Query: 69  EV-LLVPSSGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLE-YEPG 126
              +L+  SG+  +EA + + +    KVL+   GA+G R   +VE  G   +    Y+ G
Sbjct: 57  YTSVLLQGSGSYAVEAVLGSALGPQDKVLIVSNGAYGAR---MVEMAGLMGIAHHAYDCG 113

Query: 127 KAVKPE--DLDEALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAM 184
           +  +P+   +D  L  +P +  + + ++ET+TG+LNP+ E+  +A  + K   VDA+S+ 
Sbjct: 114 EVARPDVQAIDAILNADPTISHIAMVHSETTTGMLNPIDEVGALAHRYGKTYIVDAMSSF 173

Query: 185 GGADIKFDKWELDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPLYIKY 244
           GG  +      +D + SS+ K     PG A     E+ +  A K   R    D+    + 
Sbjct: 174 GGIPMDIAALHIDYLISSANKCIQGVPGFAFVIAREQKL-AACKGHSRSLSLDLYAQWRC 232

Query: 245 LKEKEST-PSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGILA 303
           +++       T P   V      L+ + K GG     + Y++  + +  G++ +G   L 
Sbjct: 233 MEDNHGKWRFTSPTHTVLAFAQALKELAKEGGVAARHQRYQQNQRSLVAGMRALGFNTLL 292

Query: 304 EPGYESPTITAVLTPEG--IKGDEVYEAMRKRGFELAKGYGSVREKTFRIGHMGYMKFED 361
           +    SP ITA  +PE    +  E Y  ++++GF +  G  S +   FRIG++G +   D
Sbjct: 293 DDELHSPIITAFYSPEDPQYRFSEFYRRLKEQGFVIYPGKVS-QSDCFRIGNIGEVYAAD 351

Query: 362 IQEMLDNLK 370
           I  +L  ++
Sbjct: 352 ITALLTAIR 360


>gb|AAF19555.1|AC005761_3 (AC005761) 2-aminoethylphosphonate:pyruvate aminotransferase
           [Leishmania major]
           Length = 435
           
 Score =  110 bits (273), Expect = 2e-23
 Identities = 100/387 (25%), Positives = 178/387 (45%), Gaps = 27/387 (6%)

Query: 7   FKEVYEMVKPKYK--LFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFL- 63
           F E   ++ P  K  LFT GP+     V E M   +  + S++ R   V  V+ +R+ L 
Sbjct: 48  FLESLSVMLPTQKPVLFTPGPLMTSDTVKEAM---LTDYASRDIR--FVQAVKFIREELI 102

Query: 64  -----EVKKGEVLLVPSSGTGIMEASIRNGVTK-GGKVLVTIIGAFGKRYKEVVETNGRK 117
                + +K   +L   SG+  +EA+I     + GGK L+   G + ++   VV+     
Sbjct: 103 SVAGLDPQKWACILQQGSGSMGIEAAISTIFPRTGGKFLLINSGKYSEKQACVVKRLQFP 162

Query: 118 AVVLEYEPGKAVKPEDLDEALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEH--DKL 175
            V+L+   G+ +K   L+  ++ NPD+  V   ++ETSTG+L P  ++A+V +       
Sbjct: 163 MVMLKMGEGEELKMSALESIIRANPDITTVGFVHHETSTGMLYPAEQIAEVVRRELPKAK 222

Query: 176 VFVDAVSAMGGADIKFDKWELDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWY 235
           + +D +SA GG    ++K   DV+ ++  K     PG++I   + R +  A K   R   
Sbjct: 223 IIIDGISAFGGIPCDYEK-ACDVLVAAPNKCLHSVPGISI-ILARRLLIEAAKGCARSAT 280

Query: 236 FDIPLYIKYLKEKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVK 295
            D+ + +    +      TPP+  V  L   L   ++ GG     + Y+ +A++VRE VK
Sbjct: 281 LDLSMQLMSFDKSGQFAVTPPVHVVMALQQALVEYKRDGGLSGRQKTYQAKAQLVREAVK 340

Query: 296 EIGLGILAEPGYESPTITAVLTPEGIKGD------EVYEAMRKRGFELAKGYGSVREKTF 349
            +G  +    G   P+   V+    +  D        Y  + +RG  +  G  S  E TF
Sbjct: 341 AMGFTLFL--GESKPSCANVVVCVNMPRDPRWNFKRFYTYLNERGLIIYPGKASHAE-TF 397

Query: 350 RIGHMGYMKFEDIQEMLDNLKEVIEEL 376
           R G +G+    + + ++   KE ++ +
Sbjct: 398 RFGIIGHTSLANCERLMKCAKEALKSM 424


>gb|AAF28367.1|AC005766_1 (AC005766) 2-aminoethylphosphonate:pyruvate aminotransferase
           [Leishmania major]
           Length = 432
           
 Score =  110 bits (273), Expect = 2e-23
 Identities = 100/387 (25%), Positives = 178/387 (45%), Gaps = 27/387 (6%)

Query: 7   FKEVYEMVKPKYK--LFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFL- 63
           F E   ++ P  K  LFT GP+     V E M   +  + S++ R   V  V+ +R+ L 
Sbjct: 45  FLESLSVMLPTQKPVLFTPGPLMTSDTVKEAM---LTDYASRDIR--FVQAVKFIREELI 99

Query: 64  -----EVKKGEVLLVPSSGTGIMEASIRNGVTK-GGKVLVTIIGAFGKRYKEVVETNGRK 117
                + +K   +L   SG+  +EA+I     + GGK L+   G + ++   VV+     
Sbjct: 100 SVAGLDPQKWACILQQGSGSMGIEAAISTIFPRTGGKFLLINSGKYSEKQACVVKRLQFP 159

Query: 118 AVVLEYEPGKAVKPEDLDEALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEH--DKL 175
            V+L+   G+ +K   L+  ++ NPD+  V   ++ETSTG+L P  ++A+V +       
Sbjct: 160 MVMLKMGEGEELKMSALESIIRANPDITTVGFVHHETSTGMLYPAEQIAEVVRRELPKAK 219

Query: 176 VFVDAVSAMGGADIKFDKWELDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWY 235
           + +D +SA GG    ++K   DV+ ++  K     PG++I   + R +  A K   R   
Sbjct: 220 IIIDGISAFGGIPCDYEK-ACDVLVAAPNKCLHSVPGISI-ILARRLLIEAAKGCARSAT 277

Query: 236 FDIPLYIKYLKEKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVK 295
            D+ + +    +      TPP+  V  L   L   ++ GG     + Y+ +A++VRE VK
Sbjct: 278 LDLSMQLMSFDKSGQFAVTPPVHVVMALQQALVEYKRDGGLSGRQKTYQAKAQLVREAVK 337

Query: 296 EIGLGILAEPGYESPTITAVLTPEGIKGD------EVYEAMRKRGFELAKGYGSVREKTF 349
            +G  +    G   P+   V+    +  D        Y  + +RG  +  G  S  E TF
Sbjct: 338 AMGFTLFL--GESKPSCANVVVCVNMPRDPRWNFKRFYTHLNERGLIIYPGKASHAE-TF 394

Query: 350 RIGHMGYMKFEDIQEMLDNLKEVIEEL 376
           R G +G+    + + ++   KE ++ +
Sbjct: 395 RFGIIGHTSLANCERLMKCAKEALKSM 421


>gb|AAF27941.1|AC005767_2 (AC005767) 2-aminoethylphosphonate:pyruvate aminotransferase
           [Leishmania major]
           Length = 435
           
 Score =  109 bits (271), Expect = 4e-23
 Identities = 100/387 (25%), Positives = 178/387 (45%), Gaps = 27/387 (6%)

Query: 7   FKEVYEMVKPKYK--LFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFL- 63
           F E   ++ P  K  LFT GP+     V E M   +  + S++ R   V  V+ +R+ L 
Sbjct: 48  FLESLSVMLPTQKPVLFTPGPLMTSDTVKEAM---LTDYASRDIR--FVQAVKFIREELI 102

Query: 64  -----EVKKGEVLLVPSSGTGIMEASIRNGVTK-GGKVLVTIIGAFGKRYKEVVETNGRK 117
                + +K   +L   SG+  +EA+I     + GGK L+   G + ++   VV+     
Sbjct: 103 SVAGLDPQKWACILQQGSGSMGIEAAIFTIFPRTGGKFLLINSGKYSEKQACVVKRLQFP 162

Query: 118 AVVLEYEPGKAVKPEDLDEALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEH--DKL 175
            V+L+   G+ +K   L+  ++ NPD+  V   ++ETSTG+L P  ++A+V +       
Sbjct: 163 MVMLKMGEGEELKMSALESIIRANPDITTVGFVHHETSTGMLYPAEQIAEVVRRELPKAK 222

Query: 176 VFVDAVSAMGGADIKFDKWELDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWY 235
           + +D +SA GG    ++K   DV+ ++  K     PG++I   + R +  A K   R   
Sbjct: 223 IIIDGISAFGGIPCDYEK-ACDVLVAAPNKCLHSVPGISI-ILARRLLIEAAKGCARSAT 280

Query: 236 FDIPLYIKYLKEKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVK 295
            D+ + +    +      TPP+  V  L   L   ++ GG     + Y+ +A++VRE VK
Sbjct: 281 LDLSMQLMSFDKSGQFAVTPPVHVVMALQQALVEYKRDGGLSGRQKTYQAKAQLVREAVK 340

Query: 296 EIGLGILAEPGYESPTITAVLTPEGIKGD------EVYEAMRKRGFELAKGYGSVREKTF 349
            +G  +    G   P+   V+    +  D        Y  + +RG  +  G  S  E TF
Sbjct: 341 AMGFTLFL--GESKPSCANVVVCVNMPRDPRWNFKRFYTYLNERGLIIYPGKASHAE-TF 397

Query: 350 RIGHMGYMKFEDIQEMLDNLKEVIEEL 376
           R G +G+    + + ++   KE ++ +
Sbjct: 398 RFGIIGHTSLANCERLMKCAKEALKSM 424


>gi|6321079 Yfl030wp [Saccharomyces cerevisiae]
           >gi|1175939|sp|P43567|YFD0_YEAST HYPOTHETICAL 41.9 KD
           PROTEIN IN HAC1-CAK1 INTERGENIC REGION
           >gi|1084694|pir||S56224 hypothetical protein YFL030w -
           yeast (Saccharomyces cerevisiae)
           >gi|836724|dbj|BAA09208.1| (D50617) YFL030W
           [Saccharomyces cerevisiae]
           Length = 385
           
 Score =  108 bits (268), Expect = 9e-23
 Identities = 97/362 (26%), Positives = 167/362 (45%), Gaps = 22/362 (6%)

Query: 13  MVKPKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLE---VKKGE 69
           M K    L   GP+     V + + V    H S E+  +    ++  R   +     K +
Sbjct: 1   MTKSVDTLLIPGPIILSGAVQKALDVPSLGHTSPEFVSIFQRVLKNTRAVFKSAAASKSQ 60

Query: 70  VLLVPSSGT---GIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKA-VVLEYEP 125
             ++  SGT    I  ++          VLV   G F  R+ + + + G +  VV   + 
Sbjct: 61  PFVLAGSGTLGWDIFASNFILSKAPNKNVLVVSTGTFSDRFADCLRSYGAQVDVVRPLKI 120

Query: 126 GKAVKPEDLDEALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVF--VDAVSA 183
           G++V  E + E L +N    AVT+T+ +TST VL+ L  +++  K+     F  VDAV +
Sbjct: 121 GESVPLELITEKLSQN-SYGAVTVTHVDTSTAVLSDLKAISQAIKQTSPETFFVVDAVCS 179

Query: 184 MGGADIKFDKWELDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERG---WYFD--- 237
           +G  + +FD+W +D   ++SQKA G P GL+I   S RF++ A    + G    YF    
Sbjct: 180 IGCEEFEFDEWGVDFALTASQKAIGAPAGLSISLCSSRFMDYALNDSKNGHVHGYFSSLR 239

Query: 238 --IPLYIKYLKEKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVK 295
              P+   Y   K +  +TPP+  +  L+V L+ I + G  ++W +++ + +   ++ + 
Sbjct: 240 RWTPIMENYEAGKGAYFATPPVQLINSLDVALKEILEEGLHKRW-DLHREMSDWFKDSLV 298

Query: 296 EIGLGILAEPGYESPTITAVLTPEGIKG-DEVYEAMRKRGFELAKG-YGSVREKTFRIGH 353
             GL + +   Y S      LT   +    +V   ++  G  +A G +  +  K  RIGH
Sbjct: 299 N-GLQLTSVSRYPSNMSAHGLTAVYVADPPDVIAFLKSHGVVIAGGIHKDIGPKYIRIGH 357

Query: 354 MG 355
           MG
Sbjct: 358 MG 359


>gb|AAA03070.1| (L01470) aminotransferase and dihydrorhizobitoxine synthase
           [Bradyrhizobium japonicum]
           Length = 806
           
 Score =  101 bits (250), Expect = 1e-20
 Identities = 81/307 (26%), Positives = 143/307 (46%), Gaps = 14/307 (4%)

Query: 66  KKGEVLLVPSSGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEP 125
           K   V+ +   G+  MEA+  + V++  K LV I G +G+R  +++   G +A+ L    
Sbjct: 31  KDYSVVPIQGGGSFAMEAARSSFVSRNDKPLVCINGIYGERIFKILRLWGVEALKLVKRA 90

Query: 126 GKAVKPEDLDEALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMG 185
            + + P+++ E L +NP V  + + + ET+TG++NPL  + + A+       VD +S+ G
Sbjct: 91  TEPLDPQEVAEQLSRNPGVTHLCLVHCETTTGIVNPLDAIIEEARRRGVKTIVDGMSSFG 150

Query: 186 GADIKFDKWELDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPLYIKYL 245
             DI   +   DV+ +SS K    PPGLA    S   +E A + P R +  D+      L
Sbjct: 151 AIDIDLSRGGPDVLVTSSNKCIEGPPGLAFVIASRELLEKAVQEP-RSFVLDVTHQWLSL 209

Query: 246 KEKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGI---L 302
           +      STPP   V      L I+E  G     ++   +R + VR+ + +   G+   L
Sbjct: 210 ERTGEWRSTPPTHIVQATTKALEILEGEG-----IDARRRRYEKVRDDLVQELEGVVSPL 264

Query: 303 AEPGYESPTITAVLTPEGIKG----DEVYEAMRKRGFELAKGYGSVREKTFRIGHMGYMK 358
                +SP   A   P GI      D +Y  +      +      +  ++FR+G +G ++
Sbjct: 265 LSAELQSPVCVAFSAPSGIADQAGFDGLYRHLAAHNLYIYSKL-HLATRSFRVGCIGEIQ 323

Query: 359 FEDIQEM 365
              I+++
Sbjct: 324 PSWIEQL 330


>pir||C47293 serine--pyruvate aminotransferase homolog RtxA - Bradyrhizobium
           japonicum (fragment)
           Length = 352
           
 Score =  101 bits (250), Expect = 1e-20
 Identities = 81/307 (26%), Positives = 143/307 (46%), Gaps = 14/307 (4%)

Query: 66  KKGEVLLVPSSGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEP 125
           K   V+ +   G+  MEA+  + V++  K LV I G +G+R  +++   G +A+ L    
Sbjct: 26  KDYSVVPIQGGGSFAMEAARSSFVSRNDKPLVCINGIYGERIFKILRLWGVEALKLVKRA 85

Query: 126 GKAVKPEDLDEALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMG 185
            + + P+++ E L +NP V  + + + ET+TG++NPL  + + A+       VD +S+ G
Sbjct: 86  TEPLDPQEVAEQLSRNPGVTHLCLVHCETTTGIVNPLDAIIEEARRRGVKTIVDGMSSFG 145

Query: 186 GADIKFDKWELDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERGWYFDIPLYIKYL 245
             DI   +   DV+ +SS K    PPGLA    S   +E A + P R +  D+      L
Sbjct: 146 AIDIDLSRGGPDVLVTSSNKCIEGPPGLAFVIASRELLEKAVQEP-RSFVLDVTHQWLSL 204

Query: 246 KEKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKEIGLGI---L 302
           +      STPP   V      L I+E  G     ++   +R + VR+ + +   G+   L
Sbjct: 205 ERTGEWRSTPPTHIVQATTKALEILEGEG-----IDARRRRYEKVRDDLVQELEGVVSPL 259

Query: 303 AEPGYESPTITAVLTPEGIKG----DEVYEAMRKRGFELAKGYGSVREKTFRIGHMGYMK 358
                +SP   A   P GI      D +Y  +      +      +  ++FR+G +G ++
Sbjct: 260 LSAELQSPVCVAFSAPSGIADQAGFDGLYRHLAAHNLYIYSKL-HLATRSFRVGCIGEIQ 318

Query: 359 FEDIQEM 365
              I+++
Sbjct: 319 PSWIEQL 325


>emb|CAA60241.1| (X86528) aspC [Clostridium perfringens]
           Length = 160
           
 Score = 92.8 bits (227), Expect = 6e-18
 Identities = 52/140 (37%), Positives = 77/140 (54%), Gaps = 2/140 (1%)

Query: 76  SGTGIM--EASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPED 133
           SG GI+  EA+  +   KG KVLV   G +G+ +   V   G +      +  K +  E 
Sbjct: 17  SGEGILGLEAACASLTEKGDKVLVLDNGLYGRWFDGFVTMYGGEVTYFSGDYTKEIDVEA 76

Query: 134 LDEALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDK 193
           L + L+KN D +  T+ + +T TGVLNP+ ++  + K +  L  VD+VSAM G + K DK
Sbjct: 77  LSKFLEKNNDFKYATVVHCDTPTGVLNPIDKICPLLKSYGILTVVDSVSAMVGEEFKVDK 136

Query: 194 WELDVVFSSSQKAFGVPPGL 213
           W++D+    SQKAF    GL
Sbjct: 137 WQIDIALGGSQKAFSADQGL 156


>emb|CAA58024.1| (X82783) serine:pyruvate aminotransferase [Drosophila melanogaster]
           Length = 173
           
 Score = 80.4 bits (195), Expect = 3e-14
 Identities = 45/166 (27%), Positives = 90/166 (54%), Gaps = 2/166 (1%)

Query: 57  ERLRDFLEVKKGEVLLVPSSGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGR 116
           E ++   +      + +  +G   MEA++ N +  G  VL+ I G +G R  ++    G 
Sbjct: 8   EGIKYIFQTLNDATMCISGAGHSGMEAALCNLIEDGDVVLMGITGVWGHRAGDMARRYGA 67

Query: 117 KAVVLEYEPGKAVKPEDLDEALKKNPDVEAVTITYNETSTGVLNP-LPELAKVAKEHDKL 175
           +   +E   G+A+  E++  A + +   +   I   ++STG++   + EL ++ +++D  
Sbjct: 68  EVHYVEASFGRALSHEEITFAFEGHRP-KVFFIAQGDSSTGIIQQNIRELGELCRKYDCF 126

Query: 176 VFVDAVSAMGGADIKFDKWELDVVFSSSQKAFGVPPGLAIGAFSER 221
           + VD V+++GG +   D+W++DV ++ SQK+ G P GL   +FS+R
Sbjct: 127 LIVDTVASLGGTEFLMDEWKVDVAYTGSQKSLGGPAGLTPISFSKR 172


>emb|CAC08322.1| (AL392149) putative aminotransferase [Streptomyces coelicolor
           A3(2)]
           Length = 363
           
 Score = 76.5 bits (185), Expect = 5e-13
 Identities = 93/377 (24%), Positives = 151/377 (39%), Gaps = 28/377 (7%)

Query: 14  VKPKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTV-----ERLRDFLEVKKG 68
           +KP    F AGP     E L+ +     S     +R+  V  +     E +R+   +  G
Sbjct: 1   MKPADGRFGAGPSKVRVEALDALAATGTSLLGTSHRQAPVKNLVGKVREGIRELFRLPDG 60

Query: 69  -EVLLVPSSGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKA--VVLEYEP 125
            EV+L     T   + +    +    + L    G F  ++ +  +     A   V+  +P
Sbjct: 61  YEVILGNGGSTAFWDVATHGLIENKSQHLS--FGEFSSKFAKAAKLAPWLAEPTVVAADP 118

Query: 126 GKAVKPEDLDEALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMG 185
           G    PE   EA      V+   +T+NETSTGV  P+  +A    +   LV VDA S  G
Sbjct: 119 G--THPEARAEA-----GVDVYGLTHNETSTGVAMPIRRVA--GADEGALVLVDATSGAG 169

Query: 186 GADIKFDKWELDVVFSSSQKAFGVPPGLAIGAFSERFIEIAEKMPERG----WYFDIPLY 241
           G  +  D  E DV + + QK+F    GL IG FS   IE AE++   G     +F +P  
Sbjct: 170 GLPV--DISETDVYYFAPQKSFASDGGLWIGVFSPAAIERAERVHASGRHVPEFFSLPTA 227

Query: 242 IKYLKEKESTPSTPPMPQVFGLNVVLRIIEKMGGKEKWLEMYEKRAKMVREGVKE--IGL 299
           I     K  T +TP +  +F L   L  +   GG +      +  +  +     E     
Sbjct: 228 IDN-SRKNQTYNTPALATLFLLGEQLDWMNGQGGLDFTTARTKDSSSRLYTWADESKYAT 286

Query: 300 GILAEPGYESPTITAVLTPEGIKGDEVYEAMRKRGFELAKGYGSVREKTFRIGHMGYMKF 359
             +++P   S  I  +   + I    V + +R  G    + Y  +     R+     +  
Sbjct: 287 PFVSDPTKRSQVIGTIDFSDDIDAAAVAKVLRANGIVDTEPYRKLGRNQLRVAMFPAIDP 346

Query: 360 EDIQEMLDNLKEVIEEL 376
            D++ +   +  VIE+L
Sbjct: 347 ADVEALTKCVDHVIEKL 363


>gb|AAG13347.1|AF266227_1 (AF266227) serine-pyruvate aminotransferase [Gillichthys mirabilis]
           Length = 202
           
 Score = 75.7 bits (183), Expect = 8e-13
 Identities = 44/185 (23%), Positives = 89/185 (47%), Gaps = 1/185 (0%)

Query: 16  PKYKLFTAGPVACFPEVLEIMKVQMFSHRSKEYRKVHVDTVERLRDFLEVKKGEVLLVPS 75
           P   LF  GP    P++L      +  H   E  ++  D  + ++   + K    + +  
Sbjct: 19  PLRHLFGPGPSNVPPKILAAGGRPIIGHLHPEMFEIMNDIKKGIQYAFQQKNNMTIAMNG 78

Query: 76  SGTGIMEASIRNGVTKGGKVLVTIIGAFGKRYKEVVETNGRKAVVLEYEPGKAVKPEDLD 135
           SG   ME ++ N V  G   L+ + G +G+R  E+ E        +   PG     ++++
Sbjct: 79  SGHAAMECAVFNTVEPGENFLLPLTGIWGERVAEIAERMDANVHRMVKSPGGYFSNKEIE 138

Query: 136 EALKKNPDVEAVTITYNETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMGGADIKFDKWE 195
           + ++K+  V    +T+ E+S G+ +P+  +  + ++HD L  VD V+++G A I  D+  
Sbjct: 139 QVIEKHKPV-LFFLTHGESSAGLCHPVDGIGDICRKHDCLFLVDTVASLGAAPIFMDQQN 197

Query: 196 LDVVF 200
           +D+++
Sbjct: 198 IDILY 202


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.316    0.137    0.389 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 148192964
Number of Sequences: 2977
Number of extensions: 6570573
Number of successful extensions: 20257
Number of sequences better than 1.0e-10: 55
Number of HSP's better than  0.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 35
Number of HSP's that attempted gapping in prelim test: 20090
Number of HSP's gapped (non-prelim): 58
length of query: 383
length of database: 189,106,746
effective HSP length: 58
effective length of query: 325
effective length of database: 154,394,500
effective search space: 50178212500
effective search space used: 50178212500
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 166 (69.1 bits)