BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1817 (lhr-1) DE:large helicase-related protein (lhr-1) (912 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||B75127 large helicase-related protein (lhr-1) PAB1817 - Pyr... 1805 0.0 pir||C71004 probable ATP-dependent helicase - Pyrococcus horikos... 1359 0.0 gi|11498749 large helicase-related protein (lhr-1) [Archaeoglobu... 610 e-173 gb|AAG19610.1| (AE005050) ATP-dependent helicase; HelA [Halobact... 551 e-155 gb|AAK40723.1| ATP-dependent helicase [Sulfolobus solfataricus] 485 e-135 emb|CAC11967.1| (AL445065) Large helicase related protein [Therm... 478 e-134 pir||G72526 hypothetical protein APE2188 - Aeropyrum pernix (str... 441 e-122 pir||D75091 large helicase-related protein (lhr-2) PAB0744 - Pyr... 348 1e-94 sp|Q57742|HELX_METJA PUTATIVE ATP-DEPENDENT HELICASE MJ0294 >gi|... 348 1e-94 pir||C72521 hypothetical protein APE2144 - Aeropyrum pernix (str... 344 3e-93 emb|CAC11727.1| (AL445064) hypothetical protein [Thermoplasma ac... 335 1e-90 sp|O27830|HELX_METTH PUTATIVE ATP-DEPENDENT HELICASE MTH1802 >gi... 329 1e-88 gi|11500031 large helicase-related protein (lhr-2) [Archaeoglobu... 319 8e-86 gb|AAK41239.1| ATP-dependent helicase [Sulfolobus solfataricus] 319 1e-85 gb|AAK40467.1| ATP-dependent helicase [Sulfolobus solfataricus] 315 1e-84 sp|P95949|HELX_SULSO PUTATIVE ATP-DEPENDENT HELICASE C04010 >gi|... 315 1e-84 pir||A69140 ATP-dependent helicase - Methanobacterium thermoauto... 262 1e-68 pir||F83237 probable ATP-dependent DNA helicase PA3272 [imported... 257 5e-67 sp|P30015|LHR_ECOLI PROBABLE ATP-DEPENDENT HELICASE LHR (LARGE H... 249 1e-64 pir||A70982 probable ATP-dependent helicase lhr - Mycobacterium ... 238 3e-61 pir||T35694 ATP dependent DNA helicase - Streptomyces coelicolor... 233 5e-60 pir||G71051 probable ATP-dependent helicase LHR - Pyrococcus hor... 194 5e-48 pir||T35049 probable ATP-dependent helicase - Streptomyces coeli... 187 4e-46 gb|AAK40384.1| ATP-dependent helicase [Sulfolobus solfataricus] 145 3e-33 gi|11499982 ATP-dependent RNA helicase, putative [Archaeoglobus ... 125 2e-27 pir||E71073 hypothetical protein PH1280 - Pyrococcus horikoshii ... 122 1e-26 pir||F69164 ATP-dependent RNA helicase homolog MTH492 - Methanob... 119 1e-25 pir||F71092 ATP-dependent RNA helicase homolog PH1003 - Pyrococc... 119 2e-25 pir||B75135 DNA helicase related protein PAB0592 - Pyrococcus ab... 117 6e-25 pir||T43854 helicase [imported] - Pyrococcus furiosus >gi|337450... 115 3e-24 sp|P50830|YPRA_BACSU HYPOTHETICAL HELICASE IN PONA-COTD INTERGEN... 114 5e-24 pir||E64496 ATP-dependent RNA helicase homolog MJ1574 - Methanoc... 113 1e-23 gi|11500032 SKI2-family helicase [Archaeoglobus fulgidus] 109 1e-22 pir||B75073 ATP-dependent RNA helicase homolog PAB1722 - Pyrococ... 109 1e-22 gb|AAK42601.1| DNA helicase related protein [Sulfolobus solfatar... 105 3e-21 pir||H82418 ATP-dependent RNA helicase, DEAD box family VCA0768 ... 101 5e-20 dbj|BAB05483.1| (AP001513) ATP-dependent RNA helicase [Bacillus ... 100 1e-19 dbj|BAA34994.1| (AB017003) DjVLGB [Dugesia japonica] 98 4e-19 sp|P34668|YO12_CAEEL PUTATIVE ATP-DEPENDENT RNA HELICASE ZK686.2... 98 6e-19 dbj|BAA91812.1| (AK001652) unnamed protein product [Homo sapiens] 96 2e-18 pir||S01676 ATP-dependent RNA helicase homolog - fruit fly (Dros... 94 5e-18 pir||A31922 ATP-dependent RNA helicase homolog - fruit fly (Dros... 94 5e-18 gb|AAF44917.1|AE003406_122 (AE003416) symbol=vas; synonym=BG:DS0... 94 5e-18 pir||E72775 probable helicase APE0191 - Aeropyrum pernix (strain... 94 5e-18 pir||T38420 probable dna helicases - fission yeast (Schizosaccha... 94 9e-18 pir||F70354 ATP-dependent RNA helicase DeaD - Aquifex aeolicus >... 92 2e-17 prf||1413329A gene vasa [Drosophila melanogaster] 91 4e-17 pir||T39188 probable U5 snRNP-specific 200kd protein - fission y... 91 4e-17 gb|AAF58994.1| (AE003834) Dbp45A gene product [Drosophila melano... 91 6e-17 emb|CAB90153.1| (AL355013) putative atp-dependent RNA helicase [... 90 1e-16 gi|6321020 putative ATP-dependent RNA helicase; Brr2p [Saccharom... 90 1e-16 pir||H64474 hypothetical protein MJ1401 - Methanococcus jannasch... 90 1e-16 pir||D82203 ATP-dependent RNA helicase RhlE VC1407 [imported] - ... 89 2e-16 gi|9755332 C4 zinc finger DNA-binding protein of low sequence sp... 89 3e-16 gi|6320497 Ydr291wp [Saccharomyces cerevisiae] >gi|2131417|pir||... 89 3e-16 pir||A82872 ATP-dependent RNA helicase UU582 [imported] - Ureapl... 88 5e-16 gi|6321360 ATP-dependent RNA helicase CA3 of the DEAD/DEAH box f... 87 8e-16 gb|AAF48446.1| (AE003498) CG6227 gene product [Drosophila melano... 87 1e-15 pir||T36671 probable helicase - Streptomyces coelicolor >gi|4539... 86 1e-15 gb|AAC00620.1| (AC002291) Similar ATP-dependent RNA Helicase [Ar... 86 2e-15 pir||D69772 ATP-dependent RNA helicase homolog ydbR - Bacillus s... 85 2e-15 gb|AAF60892.1| (AC024876) contains similarity to SW:RPB1_CRIGR [... 85 3e-15 pir||H70414 conserved hypothetical protein aq_1328 - Aquifex aeo... 85 4e-15 dbj|BAB05104.1| (AP001511) ATP-dependent RNA helicase [Bacillus ... 84 6e-15 sp|Q64060|DDX4_RAT DEAD BOX PROTEIN 4 (VASA HOMOLOG) (RVLG) >gi|... 84 7e-15 pir||F82295 ATP-dependent RNA helicase SrmB VC0660 [imported] - ... 83 1e-14 pir||T00936 ATP-dependent RNA helicase homolog T24P15.18 - Arabi... 83 1e-14 pir||E82488 ATP-dependent RNA helicase RhlE VCA0204 [imported] -... 83 1e-14 pir||T40504 atp-dependent, dead box, rna helicase - fission yeas... 83 2e-14 pir||T27149 hypothetical protein Y54E2A.6 - Caenorhabditis elega... 82 2e-14 pir||C64440 DNA repair protein RAD24 homolog (intein-containing)... 82 2e-14 pir||I51235 DEAD box protein - African clawed frog (fragment) >g... 82 2e-14 dbj|BAB14698.1| (AK023840) unnamed protein product [Homo sapiens] 82 3e-14 sp|Q40470|IF47_TOBAC EUKARYOTIC INITIATION FACTOR 4A-7 (EIF-4A-7... 82 4e-14 gb|AAB03337.1| (U60194) RNA helicase GLH-2 [Caenorhabditis elega... 82 4e-14 gb|AAF55204.1| (AE003709) CG5205 gene product [Drosophila melano... 81 5e-14 gb|AAB64289.1| (AF007580) translation initiation factor [Zea mays] 81 5e-14 gb|AAB67607.1| (U73459) translational initiation factor eIF-4A [... 81 5e-14 dbj|BAB14906.1| (AK024391) unnamed protein product [Homo sapiens] 81 6e-14 emb|CAA94089.1| (Z70200) U5 snRNP-specific 200kD protein [Homo s... 81 6e-14 sp|Q41741|IF4A_MAIZE EUKARYOTIC INITIATION FACTOR 4A (EIF-4A) (E... 81 6e-14 pir||S52019 translation initiation factor eIF-4A.7 - common tobacco 81 6e-14 gb|AAF39890.1| (AC006661) contains similarity to Pfam families P... 81 6e-14 gb|AAF53963.1| (AE003669) CG9253 gene product [Drosophila melano... 81 6e-14 gb|AAA34666.1| (L00683) ATP-dependent RNA helicase [Saccharomyce... 80 8e-14 gi|6323021 putative ATP dependent RNA helicase; Drs1p [Saccharom... 80 8e-14 pir||C69813 RNA helicase homolog yfmL - Bacillus subtilis >gi|24... 80 8e-14 pir||B75191 probable ATP-dependent RNA helicase PAB2313 - Pyroco... 80 8e-14 gb|AAK42222.1| ATP-dependent RNA helicase [Sulfolobus solfataricus] 80 1e-13 sp|P41382|IF4U_TOBAC EUKARYOTIC INITIATION FACTOR 4A-10 (EIF-4A-... 80 1e-13 sp|Q40467|IF4Y_TOBAC EUKARYOTIC INITIATION FACTOR 4A-14 (EIF-4A-... 80 1e-13 sp|Q09719|YA47_SCHPO PUTATIVE ATP-DEPENDENT RNA HELICASE C31A2.0... 80 1e-13 emb|CAA11679.1| (AJ223948) RNA helicase [Homo sapiens] 80 1e-13 pir||T39411 RNA helicase - fission yeast (Schizosaccharomyces po... 80 1e-13 sp|Q58083|Y669_METJA PUTATIVE ATP-DEPENDENT RNA HELICASE MJ0669 ... 79 2e-13 pir||S52023 translation initiation factor eIF-4A.14 - common tob... 79 2e-13 pir||T22942 hypothetical protein F58G11.2 - Caenorhabditis elega... 79 2e-13 gb|AAD20136.1| (AF091502) autoaggregation-mediating protein [Lac... 79 2e-13 sp|P41379|IF42_NICPL EUKARYOTIC INITIATION FACTOR 4A-2 (EIF-4A-2... 79 2e-13 gi|11497691 ATP-dependent RNA helicase, putative [Archaeoglobus ... 79 2e-13 pir||A71223 hypothetical protein PH0044 - Pyrococcus horikoshii ... 78 3e-13 gb|AAG20465.1| (AE005119) DNA repair protein; Rad24b [Halobacter... 78 3e-13 pir||S52020 translation initiation factor eIF-4A.15 - common tob... 78 4e-13 pir||C69187 conserved hypothetical protein MTH656 - Methanobacte... 78 4e-13 pir||S52018 translation initiation factor eIF-4A.11 - common tob... 78 6e-13 gb|AAG12945.1|AC073944_8 (AC073944) ethylene-responsive RNA heli... 78 6e-13 sp|Q40465|IF4V_TOBAC EUKARYOTIC INITIATION FACTOR 4A-11 (EIF-4A-... 77 7e-13 sp|P73421|RECQ_SYNY3 ATP-DEPENDENT DNA HELICASE RECQ >gi|7469265... 77 7e-13 emb|CAC11964.1| (AL445065) DNA helicase related protein [Thermop... 77 7e-13 gi|6320041 (putative) DEAD box RNA helicase; Dhh1p [Saccharomyce... 77 9e-13 sp|P41378|IF4A_WHEAT EUKARYOTIC INITIATION FACTOR 4A (EIF-4A) (E... 77 9e-13 pir||S52017 translation initiation factor eIF-4A.9 - common tobacco 77 9e-13 sp|Q40471|IF49_TOBAC EUKARYOTIC INITIATION FACTOR 4A-9 (EIF-4A-9... 76 1e-12 pir||S53814 DEAD box protein - slime mold (Dictyostelium discoid... 76 1e-12 sp|O01836|GLH3_CAEEL ATP-DEPENDENT RNA HELICASE GLH-3 (GERMLINE ... 76 1e-12 pir||H69124 translation initiation factor eIF-4A homolog - Metha... 76 1e-12 gb|AAK42080.1| ATP-dependent RNA helicase [Sulfolobus solfataricus] 76 2e-12 sp|Q40468|IF4Z_TOBAC EUKARYOTIC INITIATION FACTOR 4A-15 (EIF-4A-... 76 2e-12 gb|AAG22819.1|AF302423_1 (AF302423) RNA helicase II/Gu [Xenopus ... 75 4e-12 dbj|BAB06103.1| (AP001515) ATP-dependent RNA helicase [Bacillus ... 75 4e-12 gb|AAF49564.2| (AE003529) CG5931 gene product [Drosophila melano... 75 5e-12 sp|P41376|IF41_ARATH EUKARYOTIC INITIATION FACTOR 4A-1 (EIF-4A-1... 75 5e-12 sp|P54475|YQFR_BACSU PROBABLE RNA HELICASE IN CCCA-SODA INTERGEN... 75 5e-12 gi|11499835 ATP-dependent RNA helicase, DEAD-family (deaD) [Arch... 75 5e-12 pir||H82390 ATP-dependent RNA helicase, DEAD box family VCA0990 ... 75 5e-12 sp|P41377|IF42_ARATH EUKARYOTIC INITIATION FACTOR 4A-2 (EIF-4A-2... 74 6e-12 sp|Q10202|YBX6_SCHPO PUTATIVE ATP-DEPENDENT RNA HELICASE C17D1.0... 74 6e-12 dbj|BAB10456.1| (AB005234) RNA helicase [Arabidopsis thaliana] 74 6e-12 gb|AAF47376.1| (AE003468) CG6994 gene product [Drosophila melano... 74 6e-12 emb|CAA73167.1| (Y12590) translation initiation factor eIF4A I [... 74 8e-12 pir||S13269 translation initiation factor eIF-4A.I - rabbit (fra... 74 8e-12 emb|CAA26842.1| (X03039) put. eIF-4A (aa 1-390) [Mus musculus] >... 74 8e-12 emb|CAA26843.1| (X03039) put. altern. eIF-4A (aa 1-370) [Mus mus... 74 8e-12 pir||S00986 translation initiation factor eIF-4A I - mouse 74 8e-12 gi|4503529 eukaryotic translation initiation factor 4A, isoform ... 74 8e-12 sp|P29562|IF41_RABIT EUKARYOTIC INITIATION FACTOR 4A-I (EIF-4A-I... 74 8e-12 sp|P34640|YOQ2_CAEEL PUTATIVE ATP-DEPENDENT RNA HELICASE ZK512.2... 74 8e-12 gb|AAB39865.1| (U81597) ATP-dependent RNA helicase [Leishmania a... 73 1e-11 dbj|BAB01768.1| (AB022215) DEAD-Box RNA helicase-like protein [A... 73 1e-11 emb|CAA73168.1| (Y12591) translation initiation factor eIF4A II ... 73 1e-11 dbj|BAA28347.1| (AB010259) DRH1 [Arabidopsis thaliana] >gi|60167... 73 1e-11 gi|6320400 Mitochondrial DEAD box RNA helicase; Mss116p [Sacchar... 73 2e-11 pir||T51347 RNA helicase RH23 [imported] - Arabidopsis thaliana ... 73 2e-11 gb|AAF21155.1|AC010926_7 (AC010926) putative Eukaryotic initiati... 73 2e-11 gb|AAF54192.1| (AE003677) CG7878 gene product [Drosophila melano... 73 2e-11 pir||JS0039 translation initiation factor eIF-4A - mouse >gi|556... 72 2e-11 gi|6321267 RNA helicase involved in rRNA processing; Rok1p [Sacc... 72 2e-11 gb|AAF24007.1|AF083031_4 (AF083031) eukaryotic initiation factor... 72 2e-11 pir||S40763 hypothetical protein ZK512.2 - Caenorhabditis elegans 72 3e-11 gb|AAD55444.1|AF181659_1 (AF181659) BcDNA.GM05306 [Drosophila me... 72 3e-11 gb|AAF59119.1| (AE003838) BcDNA:GM05306 gene product [Drosophila... 72 3e-11 pir||T09159 RNA helicase prh75 - spinach >gi|1488647|emb|CAA6819... 71 4e-11 pir||E81090 ATP-dependent RNA helicase, probable NMB1368 [import... 71 5e-11 dbj|BAB10010.1| (AB006697) RNA helicase-like protein [Arabidopsi... 71 7e-11 dbj|BAB05326.1| (AP001512) ATP-dependent DNA helicase [Bacillus ... 71 7e-11 sp|P35683|IF4A_ORYSA EUKARYOTIC INITIATION FACTOR 4A (EIF-4A) (E... 70 9e-11 gb|AAF48747.1| (AE003506) CG5800 gene product [Drosophila melano... 70 9e-11 >pir||B75127 large helicase-related protein (lhr-1) PAB1817 - Pyrococcus abyssi (strain Orsay) >gi|5458242|emb|CAB49731.1| (AJ248285) large helicase-related protein (lhr-1) [Pyrococcus abyssi] Length = 912 Score = 1805 bits (4623), Expect = 0.0 Identities = 912/912 (100%), Positives = 912/912 (100%) Query: 1 MHILLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGL 60 MHILLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGL Sbjct: 1 MHILLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGL 60 Query: 61 PPISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTP 120 PPISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTP Sbjct: 61 PPISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTP 120 Query: 121 ETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSAT 180 ETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSAT Sbjct: 121 ETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSAT 180 Query: 181 VGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWE 240 VGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWE Sbjct: 181 VGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWE 240 Query: 241 IVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALI 300 IVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALI Sbjct: 241 IVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALI 300 Query: 301 CTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSL 360 CTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSL Sbjct: 301 CTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSL 360 Query: 361 IIAKRAIEGKLERIKPYENALDVLAHFIVGLLIEYQKLNVHEPYRMAKETYPYRNLKWEH 420 IIAKRAIEGKLERIKPYENALDVLAHFIVGLLIEYQKLNVHEPYRMAKETYPYRNLKWEH Sbjct: 361 IIAKRAIEGKLERIKPYENALDVLAHFIVGLLIEYQKLNVHEPYRMAKETYPYRNLKWEH 420 Query: 421 YLEVINVLEDAGIIRREEGILKLGRRAFKYYFDNLSTIPDEVSYKVVDIGSGKVIGRLDE 480 YLEVINVLEDAGIIRREEGILKLGRRAFKYYFDNLSTIPDEVSYKVVDIGSGKVIGRLDE Sbjct: 421 YLEVINVLEDAGIIRREEGILKLGRRAFKYYFDNLSTIPDEVSYKVVDIGSGKVIGRLDE 480 Query: 481 NFVMDLEEGMEFIMHGRSWLVLEIDGENLIIKVRESENIEGAIPSWEGELIPVPYEVARE 540 NFVMDLEEGMEFIMHGRSWLVLEIDGENLIIKVRESENIEGAIPSWEGELIPVPYEVARE Sbjct: 481 NFVMDLEEGMEFIMHGRSWLVLEIDGENLIIKVRESENIEGAIPSWEGELIPVPYEVARE 540 Query: 541 VGRLRRTLLYDPRKAPDLIKGVEFNGEELELALNSLKQNTLIPSDRDIIITVLPDTVIIH 600 VGRLRRTLLYDPRKAPDLIKGVEFNGEELELALNSLKQNTLIPSDRDIIITVLPDTVIIH Sbjct: 541 VGRLRRTLLYDPRKAPDLIKGVEFNGEELELALNSLKQNTLIPSDRDIIITVLPDTVIIH 600 Query: 601 SDLGNKVNEGISRYILGFLYSKYGRVFTAKSQAHSIIIHAPFKMNPNEVKEILLKDYDTK 660 SDLGNKVNEGISRYILGFLYSKYGRVFTAKSQAHSIIIHAPFKMNPNEVKEILLKDYDTK Sbjct: 601 SDLGNKVNEGISRYILGFLYSKYGRVFTAKSQAHSIIIHAPFKMNPNEVKEILLKDYDTK 660 Query: 661 TIISKTIRDSTVYRWKMINVAKRMGALSKRARIRNVQKLFEGTIIEVETLNEVFHDKVDV 720 TIISKTIRDSTVYRWKMINVAKRMGALSKRARIRNVQKLFEGTIIEVETLNEVFHDKVDV Sbjct: 661 TIISKTIRDSTVYRWKMINVAKRMGALSKRARIRNVQKLFEGTIIEVETLNEVFHDKVDV 720 Query: 721 QKVEEVLKLIAKGEIRITGRILNEPEEIDKEHGTISMEFMVSLHHTDEEIVELFKQRIMD 780 QKVEEVLKLIAKGEIRITGRILNEPEEIDKEHGTISMEFMVSLHHTDEEIVELFKQRIMD Sbjct: 721 QKVEEVLKLIAKGEIRITGRILNEPEEIDKEHGTISMEFMVSLHHTDEEIVELFKQRIMD 780 Query: 781 SSIVMVCTNCGFSWETKVGRVINRVRELECPKCGSIMLAPLHPKDAELFKVALKKLKHGE 840 SSIVMVCTNCGFSWETKVGRVINRVRELECPKCGSIMLAPLHPKDAELFKVALKKLKHGE Sbjct: 781 SSIVMVCTNCGFSWETKVGRVINRVRELECPKCGSIMLAPLHPKDAELFKVALKKLKHGE 840 Query: 841 KLSRNEERAYIKGLKAADLLKSYKDKALLALGTYGVGVETASRVLSKASEKELIKELIKL 900 KLSRNEERAYIKGLKAADLLKSYKDKALLALGTYGVGVETASRVLSKASEKELIKELIKL Sbjct: 841 KLSRNEERAYIKGLKAADLLKSYKDKALLALGTYGVGVETASRVLSKASEKELIKELIKL 900 Query: 901 ERQYIRTKKFWD 912 ERQYIRTKKFWD Sbjct: 901 ERQYIRTKKFWD 912 >pir||C71004 probable ATP-dependent helicase - Pyrococcus horikoshii >gi|3257752|dbj|BAA30435.1| (AP000006) 912aa long hypothetical ATP-dependent helicase [Pyrococcus horikoshii] Length = 912 Score = 1359 bits (3478), Expect = 0.0 Identities = 663/914 (72%), Positives = 797/914 (86%), Gaps = 4/914 (0%) Query: 1 MHILLKKAIKEKFRELNRLQIEAFKRI-SEGKSVLIIAPTGSGKTEAAILPVMNSILKDG 59 MHI+LKKAIKEKF +LN+LQI+AFK I EG+SVLIIAPTGSGKTEAAI+PV+NSILKD Sbjct: 1 MHIVLKKAIKEKFGKLNKLQIQAFKAIYGEGESVLIIAPTGSGKTEAAIIPVINSILKDN 60 Query: 60 LPPISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITT 119 L PISCLYIAPLKALNRDLLERLKWW KTGI+++VRHGDT Q RAKQV+NPPH+LITT Sbjct: 61 LRPISCLYIAPLKALNRDLLERLKWWGEKTGIKVEVRHGDTPQSMRAKQVKNPPHILITT 120 Query: 120 PETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSA 179 PE+LPA+LT KSLR YL+NV+FV+VDE+TEL+DNKRG QLILNLKRLSLIADFIRIGLSA Sbjct: 121 PESLPAILTTKSLRKYLENVKFVIVDEITELVDNKRGIQLILNLKRLSLIADFIRIGLSA 180 Query: 180 TVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLW 239 TVGNEEE++EW I+KP LKKRYKFKVL+P+P+PED+ELAE L+V +VA RLRTLW Sbjct: 181 TVGNEEEIREWFEAKRIIKPHLKKRYKFKVLYPQPKPEDQELAEKLKVPGDVATRLRTLW 240 Query: 240 EIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKAL 299 EIVEK+K+ L+FVNTRQFAE+L HRLKTWGKPVEVHHGSLSKEARIEAERKLKEGK+KAL Sbjct: 241 EIVEKYKKALIFVNTRQFAEILGHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKIKAL 300 Query: 300 ICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQS 359 ICTSSMELGIDIG+VD VIQYMSPRQVNRLIQRAGRS+HRL EVSEAYII TGVEDYLQ Sbjct: 301 ICTSSMELGIDIGDVDVVIQYMSPRQVNRLIQRAGRSRHRLWEVSEAYIITTGVEDYLQG 360 Query: 360 LIIAKRAIEGKLERIKPYENALDVLAHFIVGLLIEYQKLNVHEPYRMAKETYPYRNLKWE 419 L+IAKRA+EGKLE +KPYENALDVLAHFIVGLLIEY+ L ++EPYR+AK+TYPYR L+WE Sbjct: 361 LVIAKRALEGKLEGVKPYENALDVLAHFIVGLLIEYRDLKINEPYRLAKDTYPYRKLRWE 420 Query: 420 HYLEVINVLEDAGIIRREEGILKLGRRAFKYYFDNLSTIPDEVSYKVVDIGSGKVIGRLD 479 YL V+ +LE+AGII+R E L+LGR++FKYYF+NLSTIPDEVSYKV+D+ SGK+IGRLD Sbjct: 421 DYLRVLEILEEAGIIKRHEDRLRLGRKSFKYYFENLSTIPDEVSYKVIDVVSGKLIGRLD 480 Query: 480 ENFVMDLEEGMEFIMHGRSWLVLEIDGENLIIKVRESENIEGAIPSWEGELIPVPYEVAR 539 ENFV++LEEG+EFIMHG+SWLVLEI + +IKVRESENIEGAIPSWEGELIPVPYEVA Sbjct: 481 ENFVINLEEGIEFIMHGKSWLVLEIKDD--VIKVRESENIEGAIPSWEGELIPVPYEVAI 538 Query: 540 EVGRLRRTLLYDPRKAPDLIKGVEFNGEELELALNSLKQNTLIPSDRDIIITVLPDTVII 599 EVGRLRR L+ D +A LIKGVEF +EL++A LK+N LIPSDRDI+I+V P+ VI+ Sbjct: 539 EVGRLRRELVQDKERAIRLIKGVEFEEKELDIARERLKENDLIPSDRDILISVFPNLVIV 598 Query: 600 HSDLGNKVNEGISRYILGFLYSKYGRVFTAKSQAHSIIIHAPFKMNPNEVKEILLKDYDT 659 HSD GNK NEG++RYIL FL KYG++F+A++Q++ III PFKMNP+E+K+IL + Sbjct: 599 HSDFGNKTNEGLARYILAFLSLKYGKIFSARTQSNGIIITTPFKMNPDEIKDILRIKGNV 658 Query: 660 KTIISKTIRDSTVYRWKMINVAKRMGALSKRARIRNVQKLFEGTIIEVETLNEVFHDKVD 719 + IIS+ ++DS +YRWKM+NVAKRMGAL K ARI+ V++LFE TIIEVET NE+FHDKVD Sbjct: 659 REIISRALKDSPIYRWKMLNVAKRMGALRKDARIKKVERLFEDTIIEVETFNEIFHDKVD 718 Query: 720 VQKVEEVLKLIAKGEIRITGRILNEPEEIDKEHGTISMEFMVSLHHTDEEIVELFKQRIM 779 V++V VLK I GEIR+ GRIL EP ++ E+ + EF+++ ++EI LFK++++ Sbjct: 719 VERVNTVLKKIKDGEIRVKGRILEEPTSLELEYMRLRGEFLMTSPLDEKEIELLFKEKLL 778 Query: 780 DSSIVMVCTNCGFSWETKVGRVINRVRELECPKCGSIMLAPLHPKDAELFKVALKKLKHG 839 +SSI +VCTNCGFSWETKV R+I+R+ +++CPKCGS MLAPLHPKDAE FK++LKKLK G Sbjct: 779 ESSITLVCTNCGFSWETKVRRIIDRIGDIKCPKCGSRMLAPLHPKDAEAFKLSLKKLKSG 838 Query: 840 EKLSRNEERAYIKGLKAADLLKSYKDKALLALGTYGVGVETASRVLSKA-SEKELIKELI 898 EKL EE+AY+KGLKAADLL SY ALLAL TYGVGV+TA+R+LS++ SE+ LIKEL+ Sbjct: 839 EKLFEKEEKAYLKGLKAADLLNSYGKNALLALATYGVGVKTATRILSRSYSEEMLIKELM 898 Query: 899 KLERQYIRTKKFWD 912 +LE++YIRT+KFW+ Sbjct: 899 ELEKRYIRTRKFWE 912 >gi|11498749 large helicase-related protein (lhr-1) [Archaeoglobus fulgidus] >gi|7446074|pir||D69393 large helicase-related protein (lhr-1) homolog - Archaeoglobus fulgidus >gi|2649437|gb|AAB90094.1| (AE001024) large helicase-related protein (lhr-1) [Archaeoglobus fulgidus] Length = 892 Score = 610 bits (1555), Expect = e-173 Identities = 369/921 (40%), Positives = 546/921 (59%), Gaps = 68/921 (7%) Query: 15 ELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP-ISCLYIAPLKA 73 EL LQ+EAF++I GK VLIIAPTGSGKTEAAI+P+ ++LK P I +YI PL+A Sbjct: 17 ELTELQLEAFRKILSGKDVLIIAPTGSGKTEAAIIPIFEAMLKMEKPEGIVAIYITPLRA 76 Query: 74 LNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKSLR 133 LNRD+L R++ GIR+DVRHGDT +RA+Q R PPH+LITTPET L K+LR Sbjct: 77 LNRDMLRRIRGIAEFLGIRVDVRHGDTPDSQRARQSRKPPHLLITTPETFQILFLGKNLR 136 Query: 134 PYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGNEEEVKEWLGV 193 LKNVR+VVVDE+ ELID++RG QL + L+RL +A F IGLSATV + V ++G Sbjct: 137 KALKNVRYVVVDEIHELIDSERGVQLSVALERLREMARFQTIGLSATVSRPKLVSRFVGA 196 Query: 194 D-EIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEKHKRVLVFV 252 D E+++ +K Y+ +V+ P D++LA L VD E+A L+ + + V++H L+FV Sbjct: 197 DAEVLEWKAEKEYEIEVVKPEV---DEKLAAKLGVDAEIAGELKFIADAVKEHGSALIFV 253 Query: 253 NTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIG 312 NTRQ AE L +LK VEVHHGSLS+E R+EAE + +G++ ALICTSSMELGIDIG Sbjct: 254 NTRQTAEALGIKLKKL-IDVEVHHGSLSRETRVEAEERFAKGELDALICTSSMELGIDIG 312 Query: 313 EVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLE 372 V+ V+QY SPRQ RL+QR GRS H L VS+ Y++A+ +D L+S +I +RA EG LE Sbjct: 313 HVNLVVQYNSPRQAVRLVQRVGRSGHGLGRVSKGYVVASSFDDILESAVIVRRAKEGLLE 372 Query: 373 RIKPYENALDVLAHFIVGLLIEYQKLNVHEPYRMAKETYPYRNLKWEHYLEVINVLEDAG 432 + + + DVLA+ I L +EY +++ + +R+ K +PYRNL +E + EV N L G Sbjct: 373 DAEIHFKSFDVLANQICALALEYGRIDAEKAHRIVKRAFPYRNLTFEEFDEVCNFLARIG 432 Query: 433 IIRREEGILKLGRRAFKYYFDNLSTIPDEVSYKVVDIGSGKVIGRLDENFVMDLEEGMEF 492 I +EG + R +Y+++N+S IPDE Y+VVD+ SGK IG LDE+F+ G F Sbjct: 433 KIFYDEGEIGARRNTRRYFYENISMIPDEKHYRVVDVSSGKTIGSLDESFLSTF-SGEIF 491 Query: 493 IMHGRSWLVLEIDGENLIIKVRESENIEGAIPSWEGELIPVPYEVAREVGRLRRTL--LY 550 M G W VL +D +++V E + EG IPSW GE IPVP+EVA+EVG LR L L Sbjct: 492 AMKGELWRVLSVDE---VVRV-EPVSAEGEIPSWVGEEIPVPFEVAQEVGMLRNWLAGLI 547 Query: 551 DPRKAPDLIKGVEFNGE---ELELALNSLKQNTLIPSDRDIIITVLPDTVIIHSDLGNKV 607 + +K + G+ ++ +++ +P D I I + V++++ G+KV Sbjct: 548 KAKGEKAALKALGAKGDVSVVVKTLREQIEKGFAVPYDSHITIEGSENVVVVNACFGHKV 607 Query: 608 NEGISRYILGFLYSKYGRVFTAKSQAHSIIIHAPFKMNPNEVKEIL--LKDYDTKTIISK 665 NE + R + L ++ G + + I + +P K P EV+ IL ++ +++ + Sbjct: 608 NETLGRILALLLTARRGSSVAVEIDPYRIKL-SPAK--PEEVESILKSIQPEAVESLAER 664 Query: 666 TIRDSTVYRWKMINVAKRMGALSK-----RARIRNVQKLFEGTIIEVETLNEVFHDKVDV 720 + D+ + +WK++N A++ G LSK R +R++ + T I E L E+F +K+DV Sbjct: 665 AVFDTRLMQWKVVNAARKFGFLSKEDELSRINVRSLVVKLKDTPIYREALREIFVEKMDV 724 Query: 721 QKVEEVLKLIAKGEIRITGRILNEPEEIDKEHGTISMEFMVSLHHTDEEIVELFKQRIMD 780 ++ EV++ I+ GEI ++ + NE I +M+ + + E I+ F++R+ Sbjct: 725 ERTAEVVEKISSGEIEVS--VYNELSPISLAARQRAMDILAV--KSSEAILRAFRERLEK 780 Query: 781 SSIVMVCTNCGFSWETKVGRVINRVRELECPKCGSIMLA-------PLHPKDAELFKVAL 833 + + C NC + +V C KCGS M+A P ++ ELFK+A Sbjct: 781 EVVRVYCLNCRACYTERV----ESFERFTCIKCGSKMIAVFNSRRKPEEFRERELFKLAN 836 Query: 834 KKLKHGEKLSRNEERAYIKGLKAADLLKSYKDKALLALGTYGVGVETASRVLSK--ASEK 891 + HG+ +A+ AL T+G+G +TA+R+LS+ E Sbjct: 837 LVMAHGK-------------------------RAVYALSTFGIGADTAARLLSRYYLEED 871 Query: 892 ELIKELIKLERQYIRTKKFWD 912 + K LI+ ER YIRT++FWD Sbjct: 872 DFFKALIEAERNYIRTRRFWD 892 >gb|AAG19610.1| (AE005050) ATP-dependent helicase; HelA [Halobacterium sp. NRC-1] Length = 946 Score = 551 bits (1404), Expect = e-155 Identities = 334/940 (35%), Positives = 525/940 (55%), Gaps = 45/940 (4%) Query: 5 LKKAIKEK-FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP- 62 ++ A+ E+ F Q A +++G++ L++APTG+GKTE A+LPV ++++ DG PP Sbjct: 19 VRNALSERGFTTPTEPQRRAVPALADGRNGLVVAPTGTGKTETAMLPVFDALVSDGGPPD 78 Query: 63 -ISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPE 121 LY+ PL+ALNRD+ ERL WW G+ +DVRHGDTT Y+R +Q +PP VL+TTPE Sbjct: 79 GFGALYVTPLRALNRDMRERLDWWGETLGLEVDVRHGDTTDYQRRQQATDPPDVLVTTPE 138 Query: 122 TLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFI-RIGLSAT 180 TL A+LT +LR L +V VVVDEV EL KRGAQL + L+RL +A + RIGLSAT Sbjct: 139 TLQAMLTGSTLRDGLADVEHVVVDEVHELAGAKRGAQLAIGLERLVEVAGRVQRIGLSAT 198 Query: 181 VGNEEEVKEWLGVD---EIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRT 237 VG+ E+ +L EI++ + F+V P D+ LA L +A+ +R Sbjct: 199 VGDPHEIGAFLTGGRGCEIIEVDVTSNVSFEVREPAVTDADERLASELLTTPAMASHVRA 258 Query: 238 LWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVK 297 + EIV++H VL+FVNTRQ AE L R K + VHHGSLSK+ARI+ E + K G + Sbjct: 259 IREIVDRHDSVLIFVNTRQTAEALGSRFKELDANIGVHHGSLSKDARIDVEDRFKSGDLD 318 Query: 298 ALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYL 357 L+CTSSMELGID+G +D V+QY SPR+V RL+QR GR+ H VSE +I +D L Sbjct: 319 GLLCTSSMELGIDVGGIDHVVQYNSPREVKRLLQRVGRAGHSRDAVSEGTVITGSTDDTL 378 Query: 358 QSLIIAKRAIEGKLERIKPYENALDVLAHFIVGLLIEYQKLNVHEPYRMAKETYPYRNLK 417 ++L +A RA EG +E + + +LD +A+ IVG++++ + Y + YP++ L Sbjct: 379 EALAVADRANEGAVEDTQVHHGSLDTVANQIVGVVMDVGETEAWHAYNIITRAYPFKQLT 438 Query: 418 WEHYLEVINVLEDAGIIRREEG--ILKLGRRAFKYYFDNLSTIPDEVSYKVVDIGSGKVI 475 E + V L ++ +E + ++YY+ NLS IPDE +Y+V D+ G+ + Sbjct: 439 EETFRAVAMELHRNRVVYVDEDDDTISTSGGTWQYYYANLSMIPDEETYEVYDMAGGRQV 498 Query: 476 GRLDENFVMDLEE-GMEFIMHGRSWLVLEIDGENLIIKVRESENIEGAIPSWEGELIPVP 534 G LDE FV++ E G F+ G W + ID ++ ++V E+ G +PSW G+ IPVP Sbjct: 499 GTLDERFVVNFAEPGATFVQRGEMWRITNIDEDDQQVEVSPIEDPAGEVPSWTGQEIPVP 558 Query: 535 YEVAREVGRLRRTL-----LYDPRKAPDLIKGVEFN------GEELE-LALNSLKQNTLI 582 Y VA+ VG +R T P+ A + G L+ +A + +Q+ + Sbjct: 559 YAVAQAVGGMRATGGRQLGTGTPKDAVARDVAARYPTTHRTAGSALDRMARHVTEQDAPV 618 Query: 583 PSDRDIIITVLPDTVIIHSDLGNKVNEGISRYILGFLYSKYGRVFTAKSQAHSIIIHAPF 642 PS I++ TV++++ G++VNE + R + L + G + + I + P Sbjct: 619 PSAERIVVEQAGSTVVVNACFGHEVNETLGRLVSALLGQQTGSSVGLDAGPYRIELEVPS 678 Query: 643 KMNPNEVKEILLKDYD---TKTIISKTIRDSTVYRWKMINVAKRMGALSK-----RARIR 694 +++ +V + L+D D ++ +++ S ++ + VA + GAL + + Sbjct: 679 RVSATDVVAV-LRDTDPDHVAGLLELSLKQSETLKFTLAQVAAKFGALKRWKGRDGVGLS 737 Query: 695 NVQKLFEGTIIEVETLNEVFHDKVDVQKVEEVLKLIAKGEIRITGRILNEPEEIDKEHGT 754 + EGT + E + EVFH +DV + +VL + GE+ + I+ E + + Sbjct: 738 RLLGALEGTPVYEEAIREVFHTTLDVARASDVLARVQSGELGV--EIVGERTAVGAGGRS 795 Query: 755 ISMEFMVSLHHTDEEIVELFKQRIMDSSIVMVCTNCG-FSWETKVGRVINRVRELECPKC 813 E +++ H D +V+ K RI D + + C +C +S ET V RV + + ECP+C Sbjct: 796 AGTE-LLTPEHADASVVQTIKDRIQDDRVKLFCVHCADWSHETMVRRVTD---QPECPRC 851 Query: 814 GSIMLAPLHPKDAELFKVALKKLKHGEKLSRNEERAYIKGLKAADLLKSYKDKALLALGT 873 GS +A L P E+ K E+ R +RAY + A +++S+ +A++AL Sbjct: 852 GSTRIAALSPWADEVITAVRADDKDDEQDDRT-QRAY----RNASIVQSHGKRAVIALSA 906 Query: 874 YGVGVETASRVLS--KASEKELIKELIKLERQYIRTKKFW 911 GVG A+RV++ + +E E +++++ ER+Y RTK FW Sbjct: 907 RGVGPRNAARVINRHRETEAEFYRDILEREREYARTKAFW 946 >gb|AAK40723.1| ATP-dependent helicase [Sulfolobus solfataricus] Length = 913 Score = 485 bits (1234), Expect = e-135 Identities = 323/929 (34%), Positives = 506/929 (53%), Gaps = 63/929 (6%) Query: 13 FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLK 72 + +L +Q A ++ GK+VLIIAPTG GKTEAAILP+ +I KD IS LYI PL+ Sbjct: 17 YEDLTPIQKIAIPKVLSGKNVLIIAPTGYGKTEAAILPIFYTIFKDKPEKISTLYITPLR 76 Query: 73 ALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKSL 132 ALNRDL RL+ I ++VRHGD++Q R + + NPP VL+ TPETL L+ + Sbjct: 77 ALNRDLELRLRRLGEAFNISVNVRHGDSSQKERKEILDNPPDVLLVTPETLLYLVLNDTF 136 Query: 133 RPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIR---IGLSATVGNEEEVKE 189 R Y N++++++DE+ E++D KRG +L + ++R+ IA + IG+SAT+G+ E K Sbjct: 137 RKYFTNLKWIIIDELQEMLDEKRGIELSVLIQRIKKIATRNKIQLIGISATIGDVEIAKR 196 Query: 190 WL---GVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEKHK 246 +L G EI K K ++ P+ +D +LA L + + ARL L EI++ +K Sbjct: 197 YLDREGEVEIANINAIKDIKVDLILPKVEKKDADLAVKLGLRPDTIARLEKLNEIIKNNK 256 Query: 247 RVLVFVNTRQFAEVLAHRL-KTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSM 305 +++F NTR+ +E +A++L + + HHGSLS+E RI+ E K G + A++ TSS+ Sbjct: 257 PIIIFTNTRETSEFIANQLMSNYSLKIASHHGSLSREIRIKTENDFKNGNIDAIVATSSL 316 Query: 306 ELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYII-ATGVEDYLQSLIIAK 364 ELGIDIG ++ V+QYMSPRQV RLIQR GRS H++ S Y+I + + D L+ I + Sbjct: 317 ELGIDIGRINLVVQYMSPRQVIRLIQRVGRSGHKIGRTSIGYVIPSEDLFDILECRAIIE 376 Query: 365 RAIEGKLERIKPYENALDVLAHFIVGLLIEYQKLNVHEPYRMAKETYPYRNLKWEHYLEV 424 G LE+ EN LDV AH I G+++E K N E + + ++ + N E + V Sbjct: 377 ALYSGYLEKPLFEENPLDVAAHEIAGMVLEGYK-NPKEMMEILRNSFYFENFTDEMFENV 435 Query: 425 INVLEDAGII-RREEGILKLGRRAFKYYFDNLSTIPDEV-SYKVVDIGSGKVIGRLDENF 482 I +LE A I+ RRE+G L RR +KYY+ + IPD + SY V+D + IG LDE+F Sbjct: 436 IELLESAKIVKRREDGSLFPSRRIWKYYY-TTNMIPDSIRSYIVIDHATNMKIGTLDEDF 494 Query: 483 VMDLEEGMEFIMHGRSWLVLEIDGENLIIKVRESENIEGAIPSWEGELIPVPYEVAREVG 542 V+ L+E FI+ R W V+ I+ + + ++ E +N G +PSW GE IPV E+AR+V Sbjct: 495 VVTLDEDSVFILGSRLWKVVSIENDRIFVERAELKN--GILPSWFGESIPVEKEIARKVY 552 Query: 543 RLRRTLLYDPRKAPDLIKGVEFNGEELELALNSLKQN-TLIPSDRDIIITVLPDTVIIHS 601 + + R+ D E+ +K+ + D ++ V + +I+HS Sbjct: 553 EYIYAVEKEKRETED--------NSLAEVVREYMKRGYPELRPDLILVEIVKNNLIIVHS 604 Query: 602 DLGNKVNEGISRYILGFLYSKYGRVFTAKSQAHSIIIHAPFKMNPNEVKEILLKDYDTK- 660 G++ N + I L + T ++ + I I + + N++++I+ T Sbjct: 605 PFGSRGNNTLGAIISVMLDVEKQTKTTYRADPYHIAISSVLPITKNDMEKIVSTLNSTPI 664 Query: 661 ----TIISKTIRDSTVYRWKMINVAKRMGALSKRARI---RNVQKLFEGTIIEVETLNEV 713 I+ K I++S ++WK++ KR G + I ++ K + TII E + E+ Sbjct: 665 DRIIEILKKGIKESPQFKWKLLVEIKRFGMIDPEKEITLTSSIIKAYGDTIIGEEAVKEL 724 Query: 714 FHDKVDVQKVEEV----LKLIAKGEI-----RITGRILNEPEEIDKEHGTISMEFMVSLH 764 DV+ ++E+ K++ E + +ILN DKE + Sbjct: 725 LVKNYDVEIIKELKNYNWKIVEVYEASPLAKQFLDKILNY-TSFDKEEKPL--------- 774 Query: 765 HTDEEIVELFKQRIMDSSIVMVCTNCGFSWETKVGRVINRVRELECPKCGSIMLAPLHPK 824 ++E+FK+R+ + + ++C +CG WE K +IN +CPKC SI L +P Sbjct: 775 -----MIEIFKKRLENKELKLICLSCG--WEGKYS-IIN--SPSKCPKCSSIFLTATNPD 824 Query: 825 DAELFKVALKKLKHGEKLSRNEERAYIKGLKAADLLKSYKDKALLALGTYGVGVETASRV 884 D++ K+ K +K GEKL+ E R + A Y +L+AL T GVG +V Sbjct: 825 DSDSVKIVRKAIK-GEKLTSKERRQLEDLKRVASFFPDYGKYSLIALATNGVGPSNLGKV 883 Query: 885 LSKAS--EKELIKELIKLERQYIRTKKFW 911 LSK + E E LI E+++IRT+K+W Sbjct: 884 LSKLNEGENEFYMALIDEEKRFIRTRKYW 912 >emb|CAC11967.1| (AL445065) Large helicase related protein [Thermoplasma acidophilum] Length = 894 Score = 478 bits (1218), Expect = e-134 Identities = 310/906 (34%), Positives = 498/906 (54%), Gaps = 66/906 (7%) Query: 27 ISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLKALNRDLLERLKWWE 86 + EGK+VL+++PTGSGKTEAA+LPV IL++ + LYI PL+ALNRD+L RL + Sbjct: 35 VLEGKNVLLLSPTGSGKTEAAVLPVFQRILREKPKKVFALYITPLRALNRDILSRLVDYG 94 Query: 87 AKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKSLRPYLKNVRFVVVDE 146 + GI + VRH D + + + +PP +L+TTPE+L LL K+LR ++ NVR V+VDE Sbjct: 95 RELGIDVQVRHSDMSDADKRRMAESPPDILVTTPESLQILLNGKNLRRFIANVRVVIVDE 154 Query: 147 VTELIDNKRGAQLILNLKRL-SLIADFIRIGLSATVGNEEEVKEWL---GVDEIVKPPLK 202 + + +N+RG+QL L L+RL L +F RIGLSATVGN ++ +L G EI+ LK Sbjct: 155 LHDAAENERGSQLSLALERLRDLAGNFQRIGLSATVGNPGDLARFLVPNGTCEIISTTLK 214 Query: 203 KRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEKHKRVLVFVNTRQFAEVLA 262 K V+ P E+ AE++ D + A + +W+++ +H LVFVN R AE LA Sbjct: 215 KNMSIDVMVPDESSEED--AEVMGCDRQYAGAILKVWDLINRHAGSLVFVNRRFVAEDLA 272 Query: 263 HRLKT-WGK-PVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQY 320 RLK +G+ PV VHHGSLSKE R AER K G+VKALICTSS+ELGID+G +AVIQ+ Sbjct: 273 FRLKLKFGEIPVLVHHGSLSKETREFAERSFKNGEVKALICTSSLELGIDVGTANAVIQF 332 Query: 321 MSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIKPYENA 380 SPRQ+N++IQR GRS+H + + S+ Y++ T V + +++ I EGK+E ++ +N+ Sbjct: 333 NSPRQINKMIQRIGRSEHWIGKTSKGYVVCTDVIEMEEAIAIVDSIAEGKIENVQIMKNS 392 Query: 381 LDVLAHFIVGLLIEYQKLNVHEPYRMAKETYPYRNLKWEHYLEVINVLEDAGIIRREEGI 440 L LA+ I+ + K+NV + K +Y Y +L W+ Y V++ L + E+ + Sbjct: 393 LSTLANQILSEINAQGKVNVKNFFETVKRSYAYADLPWDEYYSVVSFLASTRKLWLEDEL 452 Query: 441 LKLGRRAFKYYFDNLSTIPDEVSYKVVDIGSGKVIGRLDENFV-MDLEEGMEFIMHGRSW 499 + R KYY +N+S IP E +YKV+D G GK IG LDE +V +++ G F+M G +W Sbjct: 453 MGRRRNTLKYYIENISMIPSEKNYKVIDTG-GKFIGTLDERYVASEIDAGSYFVMRGNTW 511 Query: 500 LVLEIDGENLIIKVRESENIEGAIPSWEGELIPVPYEVAREVGRLRRTLLYDPRKAPDLI 559 V+ ID + +++ ES P W GE IPV Y+V + V RK+ ++ Sbjct: 512 RVVRIDHDRILV---ESFFTPAIAPRWTGEDIPVLYDVVQRVSA--------NRKSRSIL 560 Query: 560 KGVEFNGEELELALNSLKQNTLIPSDRDIIITVLPDTVIIHSDLGNKVNEGISRYILGFL 619 ++ + L QN + DR +II D +II LG + N ++ + L Sbjct: 561 NYID---DASARKLEEWYQNDIATVDR-VIIESFNDEIIIQILLGTRGNFALAEILSNVL 616 Query: 620 YSKYGRVFTAKSQAHSIIIHAPFKMNPNEVKEIL--LKDYDTKTIISKTIRDSTVYRWKM 677 S G + I + K+ +V ++ + + + I + S ++ Sbjct: 617 TSITGESVEMDFSPYHIYLRTSRKIYAEDVMRMIKSINLENLNSYIRSSASRSRFFKSVF 676 Query: 678 INVAKRMGALS-----KRARIRNVQKLFEGTIIEVETLNEVFHDKVDVQKVEEVLKLIAK 732 + A++ G +S +R R+ + + +++ +++ ++ +D +D+ + + + Sbjct: 677 LYEARKFGIISEDADLERIRVDKIMDAYSESVVFEDSIRKLINDYMDIDAITSFIGSLDT 736 Query: 733 GEIRITGRILNEPEEIDKEHGTISMEFMVSLHHTDEEIVELFKQRIMDSSIVMVCTNCGF 792 + + +I ++ +I H + E + L T + I+E + RI++ + + C +CG Sbjct: 737 VQFVLKDKI-SKASDIFISHYS---ERVAPLRPT-KVILESVRNRILNERVTLYCVSCG- 790 Query: 793 SWETKVGRVINRVRELECPK---CGSIMLAPLHPKDAELFKVALKKLKHGEKLSRNEERA 849 RVR+++ PK CGS ++A L D E K+ ++ + Sbjct: 791 ------NVRTYRVRDIKVPKCDVCGSRLVAAL--SDFERAKI--------------DDPS 828 Query: 850 YIKG-LKAADLLKSYKDKALLALGTYGVGVETASRVL--SKASEKELIKELIKLERQYIR 906 Y K LK A L+K +A++ L GVG ETASR+L + A+E +LI+ ++ E Y R Sbjct: 829 YRKRILKNAHLVKEKGIQAVMVLSARGVGPETASRILEVTYANEDDLIRSILTAEMDYAR 888 Query: 907 TKKFWD 912 ++FWD Sbjct: 889 NRRFWD 894 >pir||G72526 hypothetical protein APE2188 - Aeropyrum pernix (strain K1) >gi|5105887|dbj|BAA81199.1| (AP000063) 977aa long hypothetical protein [Aeropyrum pernix] Length = 977 Score = 441 bits (1123), Expect = e-122 Identities = 323/952 (33%), Positives = 484/952 (49%), Gaps = 77/952 (8%) Query: 13 FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP---ISCLYIA 69 ++ L +Q +AF I G + L++APTGSGKTEAA+ P++ + + + +Y+ Sbjct: 48 YKSLLPIQEKAFPIIYRGLNALVVAPTGSGKTEAALAPLLARLRNGRVASGGGVKVVYVT 107 Query: 70 PLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTV 129 PL+ALNRDL R++ G + VRHGDT Q R + + PP ++ITTPE+L LLTV Sbjct: 108 PLRALNRDLEGRVERLAGLFGYTVQVRHGDTVQSSRRRFLERPPDIVITTPESLALLLTV 167 Query: 130 KSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIAD--FIRIGLSATVGNEE-- 185 K + LK R VVVDE+ EL+++KRG +L LNL++L L+A RIGLSATV Sbjct: 168 KRAKEVLKQARAVVVDEIHELMESKRGVELSLNLEKLELMAGRRLQRIGLSATVSRHSLY 227 Query: 186 EVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVE-K 244 LG R+ VL P+ D + + ++ + E+V+ + Sbjct: 228 RAASLLGAG---------RHVSMVLDTSPKEYDVRVVVVGDEGRFWENSVKAIAELVKGE 278 Query: 245 HKRVLVFVNTRQFAEVLAHRL-KTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTS 303 VL+F NTR E LA L + G+ V HHGSLS+ R ER KEG+VKA++ TS Sbjct: 279 GGSVLIFANTRSTVETLAFALSRELGEEVPAHHGSLSRHVRERVERDFKEGRVKAIVATS 338 Query: 304 SMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIA-TGVEDYLQSLII 362 S+ELGID+G V V+Q++SPRQV ++QRAGRS HR E S A I+ V + L+S +I Sbjct: 339 SLELGIDVGRVALVVQFLSPRQVTAMVQRAGRSGHRFGERSRAVIVTIDNVFEVLESHVI 398 Query: 363 AKRAIEGKLERIKPYENALDVLAHFIVGLLIEYQKLNVHEPYRMAKETYPYRNLKWEHYL 422 A RA++G LE I + D LAHF+ G I+ + + Y++A T PY +LK E Sbjct: 399 AFRAMKGDLEDISIPKKPYDALAHFMAGAAIDSEPPTLEGVYKLAVSTAPYEDLKMEEVE 458 Query: 423 EVINVLEDAGIIRREEGILKLGRRAFKY-YFDNLSTIPDEVSYKVVDIGSGKVIGRLDEN 481 E+ VL D +IR G KLGR + Y YF +S IPDE ++KV D+ SG+ +G + E Sbjct: 459 EIARVLSDVRVIRLGPG-GKLGRSSRTYSYFYRVSMIPDEKTFKVHDVVSGRDVGEVGER 517 Query: 482 FVM-------DLEEGMEFIMHGRSWLVLEIDGENLIIKVRESENIEGAIPSWEGELIPVP 534 F+ D ++ G+ W +LE+D + + V +EGAIP+WEGELIPV Sbjct: 518 FIQLRLMKASDPRSKPYIVLGGKVWKILEVDIDAGKVLVSPEGEVEGAIPAWEGELIPVD 577 Query: 535 YEVAREVGRLRRTLLYDPRKAPDLIKGVEFNGEELELALNSLKQN----TLIPSDRDIII 590 ++VAREV + + D L++ + + +E L+ L + + S R ++ Sbjct: 578 FKVAREVCSIMSLAMNDMEAGARLLRARRLDEKAMERVLDVLGETGRLWGTVLSWRRPVV 637 Query: 591 TVLPDTVIIHSDLGNKVNEGISRYI---------LGFLYSKYGRVFTAKSQ-------AH 634 I+++ LG++ N +S + + F Y Y VF + + AH Sbjct: 638 EEAEGLAILYACLGSRGNFALSLLLSKLMEGSVAVEFHYIPYAIVFKSPASRGLGRLVAH 697 Query: 635 SIIIHAPFKMNPNEVKEILLKDYDTKTIISKTIRDSTVYRWKMINVAKRMGALSKRAR-- 692 S+ A K+ P E +L YD +R S Y + VAKRMG + A Sbjct: 698 SLKTLA--KLEPAERLGML---YD-------AVRRSRAYLVRFYQVAKRMGVVDPDATLS 745 Query: 693 ---IRNVQKLFEGTIIEVETLNEVFHDKVDVQKVEEVLKLIAKGEIRITGRILNEPEEID 749 IR + +GT +++ET+ E+ H+K+D+ + L ++ + R+ E Sbjct: 746 LDIIRKMADAMQGTPVDIETVKELVHEKLDIDALNRFLDDVSDVAVVELQRLSPLARE-T 804 Query: 750 KEHGTISMEFMVSLHHTD-EEIVELFKQRIMDSSIVMVCTNCGFSWETKVGRVINRVREL 808 + + ++ VSL ++I+E K+R+ + IV +C +C E KV + R Sbjct: 805 LTNPYLRVDAAVSLKTLGLDKIIEAKKRRLSEKRIVFLCISCDKRHEKKVAE-LPRGTAY 863 Query: 809 ECPKCGSIMLAPLHPKD-AELFKVALKKLKHGEKLSRN--------EERAYIKGLKAADL 859 CP CGS+ LAPL P + E A + + G KLSR EERA + A + Sbjct: 864 RCPYCGSLALAPLPPTETGERLAEAYTRKRKGAKLSREEAKLAREVEERARLYISLAVEG 923 Query: 860 LKSYKDKALLALGTYGVGVETASRVLSKASEKELIKELIKLERQYIRTKKFW 911 Y +AL A G + R L E LIK E Y+ +++W Sbjct: 924 KARYIAEALSAQGVGPRRARSLLRELQLYGENRFYLALIKAEEDYVSNRRYW 975 >pir||D75091 large helicase-related protein (lhr-2) PAB0744 - Pyrococcus abyssi (strain Orsay) >gi|5458545|emb|CAB50033.1| (AJ248286) large helicase-related protein (lhr-2) [Pyrococcus abyssi] Length = 867 Score = 348 bits (884), Expect = 1e-94 Identities = 252/809 (31%), Positives = 421/809 (51%), Gaps = 90/809 (11%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGL--- 60 ++++ K KF+ Q A I +G++VLI +PTGSGKT +A L +++ ++ G Sbjct: 24 IVREWFKRKFKSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRRGK 83 Query: 61 --PPISCLYIAPLKALNRDLLERLK------------WWEAKTGIRIDVRHGDTTQYRRA 106 I C+Y++PL+ALN D+ L+ E IR+ VR DT+ Y ++ Sbjct: 84 LEDKIYCVYVSPLRALNNDIRRNLEEPLQEIRELSQELNEEIPEIRVAVRTSDTSSYEKS 143 Query: 107 KQVRNPPHVLITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRL 166 K ++ PPH+LITTPE+L L R L++V++V+VDEV L +NKRG+ L L L+RL Sbjct: 144 KMLKMPPHILITTPESLAIALNAPRFREKLRDVKWVIVDEVHALAENKRGSHLALTLERL 203 Query: 167 SLIA--DFIRIGLSATVGNEEEVKEWL-GVDEIVKP--------PLKKRYKFKVLFPRPR 215 + DF+RIGLSAT+ EEV +++ G + KP K+ K V Sbjct: 204 RELTKRDFVRIGLSATIHPLEEVAKFVFGFSDDGKPRPGLIVDVSFAKKTKITV------ 257 Query: 216 PEDKELAELLRVDVEVA--ARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRLKT----WG 269 + + +L+ V A R + E+V K L+F NTR AE +A+ LK W Sbjct: 258 --ESVVEDLVYTPANVLNEALYRRIGELVRSRKTTLIFTNTRSGAERVAYHLKKMFPEWE 315 Query: 270 KPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRL 329 +E HH SLS+E R+E E +LK G++K ++ ++S+ELGIDIG +D VI SP+ VNR Sbjct: 316 DKIEAHHSSLSREVRLEVEERLKRGELKIIVSSTSLELGIDIGTIDLVILIGSPKSVNRA 375 Query: 330 IQRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIKPYENALDVLAHFIV 389 +QR GR+ HRL EVSE I+A +D ++ ++A A + KL+RIK +N LDVL ++ Sbjct: 376 LQRIGRAGHRLHEVSEGVILALDRDDLVEVTVLAHNARKRKLDRIKIPKNPLDVLVQHLL 435 Query: 390 GLLIEYQKLNVHEPYRMAKETYPYRNLKWEHYLEVINVL--EDAGIIRR--------EEG 439 G+ +E + V E Y++ + YPY +L +E ++ V+ L E +G+ R E G Sbjct: 436 GMALE-RVWEVEEAYKVVRRAYPYHDLPFEDFINVLKYLAGEFSGLEERKVYAKIWLENG 494 Query: 440 IL-KLGRRAFKYYFDNLSTIPDEVSYKVVDIGSGKVIGRLDENFVMDLEEGMEFIMHGRS 498 K G+ Y+ N TIPDE V + K IG ++E F L G F++ GR+ Sbjct: 495 KFGKRGKMTRAIYYMNTGTIPDEAKIDVFTMDK-KYIGTVEEEFAERLIPGDIFVLAGRT 553 Query: 499 WLVLEIDGENLIIKVRESENIEGAIPSWEGELIPVPYEVAREVGRLRR---TLLYDPRKA 555 + ++ G + + R E ++ IPSW E++P+ +++A ++ + RR +LL D Sbjct: 554 YEFVKSRGNKIYVIPR--EGVKPTIPSWFSEMLPLSFDLALDIQKFRREVKSLLNDEDAE 611 Query: 556 PDLIK--GV-EFNGEELELALNSLKQNTLIPSDRDIIITVLPDTVII----HSDLGNKVN 608 L++ G+ E + + ++IP D +++ ++ + ++ H+ +G + N Sbjct: 612 LKLMEKYGIDEITAKAIISYFREQANYSVIPDDETVLVEIVKEGNVVKYFFHTLIGRRAN 671 Query: 609 EGISRYILGFLYSKYGRV---FTAKSQAHSIIIHAPFKMNPNEVKEILLKDYDTKTIISK 665 + +SR +L SK R + + +++ EV E L + + + + + Sbjct: 672 DALSR-AFAYLISKRKRCNVGMAITDNGFMLKVPRDKELSQEEVLE-LFQVENLRETLKR 729 Query: 666 TIRDSTVYRWKMINVAKR--------MGALSKRARIR-NVQKLF--------EGTIIEVE 708 + ++ + + + +VA R MG +R + N Q L E +++ E Sbjct: 730 ALDNTELLKRRFRHVANRGLLVLRRYMGRKKSLSRQQMNAQTLLNFLKRNYPEFPLLK-E 788 Query: 709 TLNEVFHDKVDVQKVEEVLKLIAKGEIRI 737 E+ DK+D++ E LK I +G+++I Sbjct: 789 VYREILEDKMDIENAELFLKWIKEGKVKI 817 >sp|Q57742|HELX_METJA PUTATIVE ATP-DEPENDENT HELICASE MJ0294 >gi|2129094|pir||G64336 large helicase related protein LHR homolog - Methanococcus jannaschii >gi|1591016|gb|AAB98279.1| (U67484) large helicase-related protein (LHR), probably RNA helicase [Methanococcus jannaschii] Length = 841 Score = 348 bits (884), Expect = 1e-94 Identities = 251/783 (32%), Positives = 415/783 (52%), Gaps = 67/783 (8%) Query: 5 LKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP-- 62 +K+ K K++ Q A K I EGK+VLI +PTGSGKT +A L +N ++K + Sbjct: 24 VKEWFKRKYKTFTPPQRYAIKEIHEGKNVLICSPTGSGKTLSAFLAGINELIKLSMENKL 83 Query: 63 ---ISCLYIAPLKALNRDLLERLK------WWEAKT------GIRIDVRHGDTTQYRRAK 107 I LY++PL+ALN D+ LK + AK IR+ VR DTT ++ + Sbjct: 84 EDRIYILYVSPLRALNNDIERNLKEPLKEIYDVAKEIGIELDEIRVAVRTSDTTSSQKQR 143 Query: 108 QVRNPPHVLITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLS 167 ++ PPH+LITTPE+L L L +++V+VDE+ L NKRG L L+L+RL+ Sbjct: 144 MLKKPPHILITTPESLAIALNSPKFSQLLSGIKYVIVDEIHALT-NKRGVHLSLSLERLN 202 Query: 168 LIADFIRIGLSATVGNEEEVKEWL---GVD-EIVKPPLKKRYKFKVLFPRPRPEDKELAE 223 IA+FIRIGLSAT+ EV ++L G D IV KK + KV+ P +D Sbjct: 203 RIANFIRIGLSATIHPLTEVAKFLVGNGRDCYIVDVSYKKEIEIKVISP---VDDF---- 255 Query: 224 LLRVDVEVAARLRTLWE-IVEKHKRVLVFVNTRQFAEVLAHRLKTWG-KPVEVHHGSLSK 281 + E++ RL L + ++E+HK L+F NTR E +A LK G + VE HH SLS+ Sbjct: 256 IYTPSEEISKRLYNLLKKLIEEHKTTLIFTNTRSATERVAFYLKQLGVEKVETHHSSLSR 315 Query: 282 EARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLL 341 E R+E E KLK+G+++ I ++S+ELG+DIG +D VI SP+ V+R +QR GRS HRL Sbjct: 316 EHRLEVEEKLKKGEIRVCISSTSLELGVDIGSIDLVILLGSPKSVSRALQRIGRSGHRLH 375 Query: 342 EVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIKPYENALDVLAHFIVGLLIEYQKLNVH 401 E S+ II +D ++++++A A GK++RI +N LDVLA +VG+ +E + +V Sbjct: 376 EKSKGIIIPFDRDDLVENVVLAYDAKIGKIDRIHIPKNCLDVLAQHLVGMALE-KVWDVD 434 Query: 402 EPYRMAKETYPYRNLKWEHYLEVINVLED--------AGIIRREEGILKLGRRAFKYYFD 453 E Y + K+ YPY++L + +L+V+N L A I ++ K G+ Y+ Sbjct: 435 EAYNLIKKAYPYKDLSKKDFLDVLNYLAGGIEEKNVYAKIWLKDNKFGKRGKSVRAIYYM 494 Query: 454 NLSTIPDEVSYKVVDIGSGKVIGRLDENFVMDLEEGMEFIMHGRSWLVLEIDGENLIIKV 513 N+ TIPDE + V I GK +G ++E F L +G F++ G+++ L G I+V Sbjct: 495 NVGTIPDETAVDV--IADGKYVGEVEEEFAEKLMKGDIFVLGGKTYKYL--GGRGNKIRV 550 Query: 514 RESENIEGAIPSWEGELIPVPYEVAREVGRLRRTLL-YDPRKAPDLIKGVEFNGEELELA 572 +E + + IP+W E +P+ Y++A ++ + R+ +L D + + E + ++ Sbjct: 551 KEVFDEKPTIPAWFSEQLPLAYDLALDIEKFRKEVLSSDIEEIREKYDIDEKTAKAIKNY 610 Query: 573 LNSLKQNTLIPSDRDIIITVLPDT----VIIHSDLGNKVNEGISRYILGFL--YSKYGRV 626 ++ + ++P D ++I + I H G + NE ++R ++ K Sbjct: 611 MDEQNKFAIVPDDEKVLIENFDEEKRRYYIFHFVAGRRANEALARAFANYISKIKKCNVR 670 Query: 627 FTAKSQAHSIIIHAPFKMNPNEVKEILLKDYDTKTIISKTIRDSTVYRWKMINVAKRMGA 686 + ++I+ K+ ++ E+ + D + ++I S + + + +VA R Sbjct: 671 ISVNDYGFALILPKNRKIKRADITELF--NLDVVKNVKESIERSEILKRRFRHVATRGFM 728 Query: 687 LSKRARIRNV---QKLFEGTII-----EV------ETLNEVFHDKVDVQKVEEVLKLIAK 732 + +R R + ++ F ++ EV ETL E+ D +D+ + + I + Sbjct: 729 ILRRYMNRKISVDRQQFNAEMLLKYCKEVNHPLYRETLREILEDSLDIDNALDYFEKIKR 788 Query: 733 GEI 735 +I Sbjct: 789 RKI 791 >pir||C72521 hypothetical protein APE2144 - Aeropyrum pernix (strain K1) >gi|5105843|dbj|BAA81155.1| (AP000063) 880aa long hypothetical protein [Aeropyrum pernix] Length = 880 Score = 344 bits (873), Expect = 3e-93 Identities = 263/826 (31%), Positives = 423/826 (50%), Gaps = 106/826 (12%) Query: 4 LLKKAIKEKFRE----LNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSIL--- 56 +L+ + E FR Q +A + +GKSVLI +PTG+GKT AA L V++ IL Sbjct: 1 MLRPYVAEWFRSTYGSFTEPQRQAIPLVKQGKSVLITSPTGTGKTLAAFLGVIDEILFLM 60 Query: 57 --KDGLPPISCLYIAPLKALNRD----LLERLKWWEAKTG--------IRIDVRHGDTTQ 102 + I +Y++PL+ALN D L E L+ E K +++ VR DTT Sbjct: 61 ENRWEEKGILAVYVSPLRALNNDIRRNLEEPLRGIEEKAREMGLEPPRVKVAVRTSDTTP 120 Query: 103 YRRAKQVRNPPHVLITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILN 162 Y + K V++PPH+LITTPE+L A L R L V++VV+DE+ EL NKRGA L+++ Sbjct: 121 YEKQKMVKDPPHILITTPESLAAALAAPKFRERLSTVKWVVLDEIHELASNKRGAHLMVS 180 Query: 163 LKRLSLIA------DFIRIGLSATVGNEEEVKEWLGV--DE-------IVKPPLKKRYKF 207 ++RL + RIGLSAT+ + V +LG DE IV K Sbjct: 181 VERLEELVREAGGKPLRRIGLSATIAPLDVVANFLGGFDDEGRPREVHIVDARFAKPIDI 240 Query: 208 KVLFPRPRPEDKELAELLR--VDVEVAARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRL 265 KV+ P +LLR D A R + E+V++H+ L+F NTR E + H+L Sbjct: 241 KVITPD--------VDLLRDPPDKINEAIYRKIAELVKQHRTTLIFTNTRSATERVVHKL 292 Query: 266 K--------TWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAV 317 K +E HH SLS+ R++ E +LK G++K ++ ++S+ELGIDIG +D V Sbjct: 293 KQILVKEGIASEDQIEAHHSSLSRNLRLDVEERLKRGELKVVVSSTSLELGIDIGYIDLV 352 Query: 318 IQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIKPY 377 I SP+ V+RL+QR GR+ HR+ +VS+ +I +D ++ ++A A++ ++R++ Sbjct: 353 ILLSSPKSVSRLLQRVGRAGHRIRDVSKGRLIVVDRDDLVECSVLADCAMKKFIDRVRIP 412 Query: 378 ENALDVLAHFIVGLLIEYQKLNVHEPYRMAKETYPYRNLKWEHYLEVINV------LEDA 431 LDVLA IVG+ IE +K + + YR+ K Y +++L +E ++ V+ LE Sbjct: 413 MKPLDVLAQHIVGMSIE-KKWRLEDAYRVVKRAYNFKDLSFEEFMSVVRFLAGKHGLEGE 471 Query: 432 GI-----IRREEGILKLGRRAFKYYFDNLSTIPDEVSYKVVDIGSGKVIGRLDENFVMDL 486 G+ + EEG+ + A Y N+ IPDE +V GK +G L+E FV L Sbjct: 472 GVYSKIWLDEEEGLFGRKKSARMIYLLNVGVIPDETKIRVY-TRDGKYVGDLEEEFVEIL 530 Query: 487 EEGMEFIMHGRSWLVLEIDGENLIIKVRESENIEGAIPSWEGELIPVPYEVAREVGRLRR 546 G F++ GR++ L+ +G +I V +++ +PSW E++P+ ++ A +VG RR Sbjct: 531 VPGDVFVLGGRTYRFLKSEGLRVI--VERADDARPTVPSWFSEMLPLSFDSALKVGEFRR 588 Query: 547 TL----LYDPRKAPD-LIKGVEFNGEE------LELALNSLKQNTLIPSDRDIIITVLPD 595 +PR A + L+K E+ EE +E L L ++PSD+ ++I P Sbjct: 589 VFSALASSNPRAAVEKLVK--EYYLEERAAATIVEYILEQLGYIGVVPSDKLVLIEYFPY 646 Query: 596 T----VIIHSDLGNKVNEGISRYILGFLYSKYGRVFTAKSQAHSIIIHAPFKMNPN-EVK 650 ++ H+ G +VN+ +SR L + G + ++ P+ + Sbjct: 647 EDGWGIVFHTLFGRRVNDALSRAYAVALSRRIGLPVRVAVTDNGFMLTVSEAGKPDASLL 706 Query: 651 EILLKDY---DTKTIISKTIRDSTVYRWKMINVAKRMGALSKRARIR---------NVQK 698 E L++D + + I+ + I + + + + +VA RM + +R + + N QK Sbjct: 707 EKLIRDVTPENIRGILEEAISRTELMKRRFKHVAARMFIVLRRYKGKEVSPERLQLNSQK 766 Query: 699 LFEGTIIEV-------ETLNEVFHDKVDVQKVEEVLKLIAKGEIRI 737 L E + E+ ET E+ D +D+ +VL+ I KGEI I Sbjct: 767 LLEVFLEEMKDSPPIRETFREILEDYMDIGAAGKVLEWIRKGEIEI 812 >emb|CAC11727.1| (AL445064) hypothetical protein [Thermoplasma acidophilum] Length = 1690 Score = 335 bits (850), Expect = 1e-90 Identities = 244/791 (30%), Positives = 410/791 (50%), Gaps = 79/791 (9%) Query: 5 LKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMN---SILKDGL- 60 + K + L Q A I G++VL+ +PTG+GKT A L ++N S+ K+G Sbjct: 21 VSKWFNSNYSSLTEPQKYAIPLIHSGRNVLVSSPTGTGKTMTAFLTIINELVSLAKEGRL 80 Query: 61 -PPISCLYIAPLKALNRDLLERLKW------------WEAKTGIRIDVRHGDTTQYRRAK 107 + C+YI+PLKAL D+ + LK+ +RI VR GDTT+ R K Sbjct: 81 EDRVYCVYISPLKALANDINKNLKFPLDGIYSIMDSEGIKVPRVRISVRSGDTTESERQK 140 Query: 108 QVRNPPHVLITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLS 167 VR PPH+LITTPE+ L+ +R L+NVR+V++DE+ E+ KRG+ L NL+RL+ Sbjct: 141 MVRKPPHILITTPESFSLALSSPKMRENLRNVRYVIIDEIHEISSTKRGSLLSANLERLN 200 Query: 168 LIAD-FIRIGLSATVGNEEEVKEWL-GVD-------EIVKPPLKKRYKFKVLFPRPRPED 218 LI+ +RIGLSAT EE+ ++L G + EIV+ +K + + P P Sbjct: 201 LISPGMVRIGLSATQSPIEEIAKYLVGFEGEKARPCEIVEVRGEKHLDLRTITPVP---- 256 Query: 219 KELAELLRVDVEVA--ARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWG-KPVEVH 275 +L RV EVA + ++V++++ L+F NTR E +A RLK+ G + +E H Sbjct: 257 ----DLTRVSYEVANDRMYDIIADLVKQYRTTLIFTNTRSGTEHVAMRLKSRGIESLEAH 312 Query: 276 HGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGR 335 H S+ K+ R+E E KLK G+++ +I ++S+ELGIDIG +D VIQ SP+ V++ +QR GR Sbjct: 313 HSSMGKDQRLEVENKLKNGELRCVITSTSLELGIDIGFIDLVIQIGSPKSVSKGLQRIGR 372 Query: 336 SKHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIKPYENALDVLAHFIVGLLIEY 395 S H + E+S+ I ++D ++ ++ K A +++R+ +N LDVLA +VG+ +E Sbjct: 373 SGHGVDELSKGIFIVFTLDDLVECAVLTKAAYSRQIDRVDIPKNPLDVLAQILVGMSLE- 431 Query: 396 QKLNVHEPYRMAKETYPYRNLKWEHYLEVINV----LEDAGI-----IRREEGILKLGRR 446 + + E Y + + +Y + L E ++ ++ LE I + RE G R Sbjct: 432 RVWRIEEAYDLLRNSYTFHELSHEEFMMTMDYLSGELESLSIYPKVWLDREAGTFGKKRS 491 Query: 447 AFKYYFDNLSTIPDEVSYKVVDIGSGKVIGRLDENFVMDLEEGMEFIMHGRSWLVLEIDG 506 YF N+ TIPDE +YK ++ GK +G L + FV L+ G F++ R++ + E Sbjct: 492 TRMIYFMNVGTIPDEANYKAIN-EKGKNVGELSDKFVERLKTGDVFVLGARTY-IFEKTV 549 Query: 507 ENLIIKVRESENIEGAIPSWEGELIPVPYEVAREVGRLRRTLL------YDPRKAPDLIK 560 N + VR ++ +PSW GE++P Y++ +G+ R + DP + Sbjct: 550 RNRVY-VRSVTGMKPTVPSWTGEMLPRSYDLGVMIGQFRDRIASMIGSGEDPTEMLINEY 608 Query: 561 GVEFNGEELELALNSLKQNTLIPSDRDIIITVLPDT-----VIIHSDLGNKVNEGISRYI 615 V+ NG ++ + IP++ +I ++ +I H LG KVN+ +SR Sbjct: 609 HVDENGARSIISYIKAQIEYGIPTENRALIEGYQESDGVYGLIFHVPLGRKVNDALSRAY 668 Query: 616 LGFLYSKYGRVFTAKSQAHSIIIHAPFKMNPNEVKEILLKDYDTKTIISKTIRDSTVYRW 675 + +KYG II+ K+ P E + + + ++ ++I ++ +++ Sbjct: 669 ALAISNKYGSNTRITITDDGFIIYTERKI-PIEEAVKTVNSSNFRDLVRRSIANTELFKQ 727 Query: 676 KMINVAKRMGALSK----------RARIRN------VQKLFEGTIIEVETLNEVFHDKVD 719 + + A R + + R ++R+ +QK + +II ET E+ D +D Sbjct: 728 RFRHCAARSLMVLRSYKGYDISVARQQLRSDRLLNELQKHEDFSIIR-ETYREIMEDLMD 786 Query: 720 VQKVEEVLKLI 730 V + E+ +K + Sbjct: 787 VPRAEQYVKSV 797 >sp|O27830|HELX_METTH PUTATIVE ATP-DEPENDENT HELICASE MTH1802 >gi|7446115|pir||H69107 ATP-dependent helicase - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622934|gb|AAB86268.1| (AE000934) ATP-dependent helicase [Methanobacterium thermoautotrophicum] Length = 862 Score = 329 bits (834), Expect = 1e-88 Identities = 255/813 (31%), Positives = 403/813 (49%), Gaps = 90/813 (11%) Query: 1 MHILLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILK--- 57 +H + + + F + Q A I G++VL+ +PTGSGKT A L +++ + + Sbjct: 18 LHPWVSEWFRRTFDDFTEAQRYAIMDIHRGRNVLVSSPTGSGKTLTAFLSIISELTRLAD 77 Query: 58 DGL--PPISCLYIAPLKALNRDL-------LERLKWWEAKTG----IRIDVRHGDTTQYR 104 DG + C+YI+PLKAL+ D+ L ++ A G IR VR GDTT Y Sbjct: 78 DGELEDSVYCIYISPLKALDNDIERNLEEPLSAIRDIAAGEGRDLEIRKAVRTGDTTSYE 137 Query: 105 RAKQVRNPPHVLITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLK 164 R++ ++ PPH+LITTPETL LL R L VR+V+VDE+ L DNKRG L L+L+ Sbjct: 138 RSRMLKKPPHILITTPETLSILLVAPKFREKLSTVRYVIVDEIHSLADNKRGVHLSLSLE 197 Query: 165 RLS-LIADFIRIGLSATVGNEEEVKEWL-----GVDE---IVKPPLKKRYKFKVLFPRPR 215 RL L+ DF RIGLSATV E V +L G + IV K ++ P Sbjct: 198 RLQHLVGDFTRIGLSATVHPLERVARFLVGYSYGSERECLIVDVSYLKELDIDLICP--- 254 Query: 216 PEDKELAELLRVDVEVA--ARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTW----- 268 + +++ D E A L +++E H+ L+F NTR E + + LK+ Sbjct: 255 -----VDDIVAADPEEIGNALYDILHDLIEDHRTTLIFTNTRSGTESVVYNLKSRFPESY 309 Query: 269 -GKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVN 327 + HH SLS+E R+E E KLK G++KA++ ++S+ELGIDIG +D V+ SP+ V+ Sbjct: 310 SDSNIMAHHSSLSREIRLETEEKLKRGELKAVVSSTSLELGIDIGYIDLVVLLSSPKSVS 369 Query: 328 RLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIKPYENALDVLAHF 387 R +QR GRS H+L + S+ I+ +D ++ +I K A+EGK++ IK EN LDVLA Sbjct: 370 RALQRIGRSGHQLHQRSKGRIVVVDRDDLVECSLILKNALEGKIDSIKVPENCLDVLAQH 429 Query: 388 IVGLLIEYQKLNVHEPYRMAKETYPYRNLKWEHYLEVINVLEDAGIIRREEGIL------ 441 I G+ IE ++ + + +Y YRNL E YL V++ L + E + Sbjct: 430 IYGMAIE-NPWDIDHALAVIRNSYCYRNLSREDYLSVLSYLAGEYVELEERYVYAKIWVD 488 Query: 442 -------KLGRRAFKYYFDNLSTIPDEVSYKVVDIGSGKVIGRLDENFVMDLEEGMEFIM 494 K G+ A Y N+ TIPD S VV G GKV+GR++E+F+ L +G F++ Sbjct: 489 YDKNQFGKRGKLARMLYSTNIGTIPDR-SAAVVKCG-GKVVGRIEEDFMEKLRKGDTFVL 546 Query: 495 HGRSWLVLEIDGENLIIKVRESENIEGAIPSWEGELIPVPYEVAREVGRLRRTL---LYD 551 GR + G + + V + IPSW E +P+ +++A ++ R R + Sbjct: 547 GGRIYRFNYARG--MTVNVTPASG-PPTIPSWFSEQLPLSFDLALDIQRFRDIMDGKFQY 603 Query: 552 PRKAPDLIKGVEFNGEELELALNSL----KQNTL---IPSDRDIIITVLP-----DTVII 599 R ++++ + E A +S+ ++ L IPS R +++ ++ Sbjct: 604 GRSRDEIMEFIMSYLHVDERAASSIYEYFREQYLYAGIPSIRRMLVEYYTGFGGRKFIVF 663 Query: 600 HSDLGNKVNEGISRYILGFLYSKYGR---------VFTAKSQAHSIIIHAPFKMNPNEVK 650 HS G +VN+ ISR + + +Y R F S+ + A ++ P ++ Sbjct: 664 HSLFGRRVNDAISRAVAYVIARRYRRDVMISVSDNGFYLSSEGKMGGLEAFRELEPENLR 723 Query: 651 EILLKDYDTKTIISKTIRD----STVYRWKMINVAKRMGALSKRARI--RNVQKLFEGTI 704 +L K D ++ R + + + K +G R +I + V +L + Sbjct: 724 NVLKKALDRTETLASRFRHCAGRALMILRRYRGEEKSVGRQQVRGKILLKFVSELDDKFP 783 Query: 705 IEVETLNEVFHDKVDVQKVEEVLKLIAKGEIRI 737 I E EV D +D++ VL+ I G++ I Sbjct: 784 ILEEARREVMEDYMDIENAIRVLEWIRDGDMEI 816 >gi|11500031 large helicase-related protein (lhr-2) [Archaeoglobus fulgidus] Length = 862 Score = 319 bits (809), Expect = 8e-86 Identities = 222/669 (33%), Positives = 353/669 (52%), Gaps = 68/669 (10%) Query: 1 MHILLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGL 60 +H L+++ K+ E Q A +G++VLI +PTGSGKT AA L ++ +++ Sbjct: 17 LHPLVREWFLSKYSEFTPPQKYAIVEAFKGRNVLITSPTGSGKTLAAFLAAISMLVEKAE 76 Query: 61 PP-----ISCLYIAPLKALNRDL-------LERLKWWEAKTGIRID-----VRHGDTTQY 103 + +Y++PLKALN D+ LE + K GI++ VR GDT Sbjct: 77 KGELEDRVYVVYVSPLKALNNDIRKNLEEPLEEIYALAEKKGIKLQKIRAAVRTGDTDAA 136 Query: 104 RRAKQVRNPPHVLITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNL 163 + KQ R PPH+LITTPETL +L L NVRF++VDE+ + +NKRG L L++ Sbjct: 137 EKQKQARKPPHILITTPETLAIVLCSPKFSKSLTNVRFLIVDEIHAIAENKRGVHLTLSM 196 Query: 164 KRLSLI--ADFIRIGLSATVGNEEEVKEWL-----GVDE---IVKPPLKKRYKFKVLFPR 213 +RL I + +RIGLSAT+ EE+ +L G + I +K KV+ P Sbjct: 197 ERLQRIQEGEMVRIGLSATISPLEEIARFLVGYNYGEERDCVIADVTFEKPMDIKVVSP- 255 Query: 214 PRPEDKELAELLRVDVE-VAARLRTLW-EIVEKHKRVLVFVNTRQFAEVLAHRLKTWGK- 270 + + E ++ RL L E V+ K L+F NTR E + + LK K Sbjct: 256 -------INDFFSASAEEISDRLYDLLAEYVKSSKTTLIFTNTRSATERVVYHLKKRLKD 308 Query: 271 -PVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRL 329 P++ HH SLSKE R+E E +LK G+++ ++ ++S+ELGIDIG +D VI SP+ +NR Sbjct: 309 FPIKAHHSSLSKEVRLEVENELKNGELRCVVSSTSLELGIDIGYIDLVILLGSPKSINRA 368 Query: 330 IQRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIKPYENALDVLAHFIV 389 +QR GRS HRL EVS I+ +D ++ ++AK A E +L+R+K LDVL +V Sbjct: 369 LQRIGRSGHRLHEVSVGRIVVVDQDDLVECTVLAKEARERRLDRVKIPRKCLDVLCQHVV 428 Query: 390 GLLIEYQKLNVHEPYRMAKETYPYRNLKWEHYLEVI-------NVLEDAGIIRR-----E 437 G+ IE + +V E + + YPYR L E +L V+ + LE + + E Sbjct: 429 GMAIE-KVWSVDEALALIRNAYPYRELTREEFLSVLRYLSGNFSELEKKKVYAKIWFDEE 487 Query: 438 EGIL-KLGRRAFKYYFDNLSTIPDEVSYKVVDIGSGKVIGRLDENFVMDLEEGMEFIMHG 496 EG+ + G+ Y+ N TIPDEV+ KV+ GK +G+++E F +L G F++ G Sbjct: 488 EGVFGRRGKMIRPIYYLNTGTIPDEVAVKVI-TKDGKRVGKVEEEFAENLLPGDIFVLAG 546 Query: 497 RSWLVLEIDGENLIIKVRESENIEGAIPSWEGELIPVPYEVAREVGRLRRTL--LYDPRK 554 +++ L+ G ++I V E E + +PSW E +P+ Y++A + + R + + + + Sbjct: 547 KTFRFLKAKGMSII--VEEVEGEKPTVPSWFSEQLPLSYDLAERIRKFRGWMEEMLEKKS 604 Query: 555 APDLIKGVEFNGEELELALNSL-------KQNTLIPSDRDIIITVLP---DTVIIHSDLG 604 ++I + N E A N++ K + IP+D +++ + H+ +G Sbjct: 605 REEIIAILMENFEIERNAANAIYRYFMEQKLFSEIPTDSKLVVEKYEAERNYYFFHTLIG 664 Query: 605 NKVNEGISR 613 + N I+R Sbjct: 665 RRANSAIAR 673 >gb|AAK41239.1| ATP-dependent helicase [Sulfolobus solfataricus] Length = 933 Score = 319 bits (808), Expect = 1e-85 Identities = 242/770 (31%), Positives = 395/770 (50%), Gaps = 74/770 (9%) Query: 5 LKKAIKEK-FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 L+K I+EK + +L R+Q +F+ IS G + L+IAPTG GKTEAA+LP++N +LK+ + P+ Sbjct: 9 LRKLIEEKNWMKLTRVQEMSFEPISNGYNTLVIAPTGYGKTEAALLPILNRMLKEDVKPV 68 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 + +YI PLKAL DLL R+ WW ++ G ++ +HG+ Q + +++ PH+++TTPE L Sbjct: 69 TVIYITPLKALINDLLYRIDWWASRLGFLVNRKHGEVPQKEKNLRLKRIPHIIVTTPEGL 128 Query: 124 PALLTVKS-LRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIA--DFIRIGLSAT 180 L S R + KNV++VVVDE+ ELI++KRG QL + L+RL DF RIGLSAT Sbjct: 129 EIDLDWASRFREHYKNVKWVVVDEIHELINSKRGTQLSILLERLKYFIGYDFQRIGLSAT 188 Query: 181 VGNEEEVKEWL-GVDE----IVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARL 235 V +E++V ++L G E I++ + ++ K+ D A + A ++ Sbjct: 189 VSDEDKVAQFLFGSSERKMKIIRLNDTRNFEIKI---NKLGNDNSFA----LWKSAAEKI 241 Query: 236 RTLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWG-KPVEVHHGSLSKEARIEAERKLKEG 294 L E K LVF N+R E L L+ G K + VHH S+S++ + AE +L+ G Sbjct: 242 NQLIE-----KPTLVFTNSRFSTERLHEELEKLGNKEIYVHHSSVSRDLKNLAEGELRNG 296 Query: 295 KVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVE 354 KA++CT ++ELGI +G++ VI P V+ +QR GRS H + V + II Sbjct: 297 NAKAVVCTKTLELGIHVGDIKKVIMLRPPTSVSSFLQRLGRSGHIVHGVPKGEIICFYDF 356 Query: 355 DYLQSLIIAKRAIEGKLERIKPY-ENALDVLAHFIVGLLIEYQKLNVHEPYRMAKETYPY 413 D L+SL + A +GK+E KP+ ++ LDV+A IVG++++ QK+++ E + + + TY Y Sbjct: 357 DVLESLALYLSAKDGKME--KPFIDDGLDVVAREIVGMILQNQKMSIEEIFNIIRGTYIY 414 Query: 414 RNLKWEHYLEVINVLEDAGIIRREEGILKLGRRAFKYYFDN--------------LSTIP 459 RNL+ L+++N L II+ EE LKLG+ FK + N S I Sbjct: 415 RNLELSKLLDLVNYLVKNNIIKIEENYLKLGQGFFKIWRFNRDAKNSWGKDFSEFFSLIN 474 Query: 460 DEVSYKVVDIGSGKVIGRLDENFVMDLEEGMEFI-MHGRSWLVLEIDGENLIIKVRESEN 518 ++ ++ + +G +G +D +V + I + G+ W VL I+ I V + Sbjct: 475 NDETFSLKH--NGITVGEIDAVYVYKHVRANDIIRISGKFWKVLRINMHKNTIDVTPANE 532 Query: 519 IEGAIPSWEGELI---PVPYEVAREVGR------LRRTLLYDPRKAPDLIKGVEFNGEEL 569 EG IP W+GE + P+ R++ L + D +IK E Sbjct: 533 GEGEIPIWKGENMSKSPLIVNYIRKIMENFNEYYLTMNEIMDKNSKESIIKIFE------ 586 Query: 570 ELALNSLKQNTLIPSDRDIIITVLPDTVIIHSDLGNKVNEGISRYILGFLYSKYGRVFTA 629 N K IPS I++ D + + +++ +S +L + KY T Sbjct: 587 ----NYRKLGLKIPSRDVILVENKEDEWLYTVVIDERISNTLSHILLYLVTKKY----TL 638 Query: 630 KSQAHSIIIHAPFKMNPNEVKEILLKDYDTK--TIISKTIRDSTVYRWKMINVAKRMGAL 687 + + S I K P ++ + ++ D K II ++I S +Y + + G + Sbjct: 639 NASSRSSIYGFSIKGTPVDLFKDIINMNDRKIIKIILRSILRSPLYIATLKEIQPSFGKI 698 Query: 688 SKRARIRNVQKLFEGTIIEVETLNEVFHDKVDVQKVEEVLKLIAKGEIRI 737 SK E + E L + ++K E ++ + +G+I+I Sbjct: 699 SK-------INTKEDKFLIKEALRQTIKRYFTIKKTLEFIRRVREGKIKI 741 >gb|AAK40467.1| ATP-dependent helicase [Sulfolobus solfataricus] Length = 875 Score = 315 bits (799), Expect = 1e-84 Identities = 237/806 (29%), Positives = 405/806 (49%), Gaps = 86/806 (10%) Query: 7 KAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDG-----LP 61 K ++K+ Q A I + +VL+ +PTGSGKT AA L +++S+ + G Sbjct: 22 KWFRQKYTTFTPPQRAAIPLIKQNYNVLVSSPTGSGKTLAAFLGILDSLFELGDNNELED 81 Query: 62 PISCLYIAPLKALNRDL-------LERLKWWEAKT-GIRIDVRHGDTTQYRRAKQVRNPP 113 + +YI+PL+ALN D+ L L+ +K +R+ +R DTT Y + K ++ PP Sbjct: 82 KVYAIYISPLRALNNDMQRNLLEPLNELRQVNSKLPDVRVGIRTSDTTPYEKQKMLKKPP 141 Query: 114 HVLITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNL---KRLSLIA 170 H+LITTPE+ +T L +V++++VDE+ EL ++KRGA L L + L Sbjct: 142 HILITTPESFGISITSPKFSQKLTDVKWIIVDEIHELANSKRGAYLSAMLELFRNLITKK 201 Query: 171 DFIRIGLSATVGNEEEVKEWL-GVDE---IVKPPLKKRYKFKVLFPRPRPEDKELAELLR 226 +F+RIGLSATV EEV ++L G D IV K KV+ P K+L Sbjct: 202 EFVRIGLSATVSPLEEVAQFLVGKDREYRIVDARFVKPVDIKVISPV-----KDLVHSSE 256 Query: 227 VDVEVAARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGK--------PVEVHHGS 278 +V+ +T+ V+KH+ L+F NTR E +A++L+ + +E HH S Sbjct: 257 SEVDKGI-YKTILNEVKKHRTTLIFTNTRHATERVAYKLRKLAENEKVFDVDAIEAHHSS 315 Query: 279 LSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKH 338 LS++ R++ E KLK+G +K ++ ++S+ELGIDIG +D VI SP+ V+RL+QR GR+ H Sbjct: 316 LSRDVRLDVEEKLKKGILKVVVSSTSLELGIDIGYIDLVILLSSPKSVSRLLQRIGRAGH 375 Query: 339 RLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIKPYENALDVLAHFIVGLLIEYQKL 398 + +S+ +I +D ++ ++AK A + K++ I +N LDVL+ IV + + Sbjct: 376 HIRSISKGRVIVVDRDDLVECSVLAKLARDRKIDSIHIPKNPLDVLSQIIVSASL-ISPI 434 Query: 399 NVHEPYRMAKETYPYRNLKWEHYLEVINVLED-----------AGIIRREEGILKLGRRA 447 + + +++ + +Y + +L Y V+ L A I +EE I+ + + Sbjct: 435 DRDDLFKILRRSYNFSDLSESDYSLVLRYLSGDFFGVELKNVYAKIRIKEEKIIYPKKGS 494 Query: 448 FKYYFDNLSTIPDEVSYKVVDIGSGKVIGRLDENFVMDLEEGMEFIMHGRSWLVLEIDGE 507 ++ N TIPDE VV + + +G L+E FV L G F++ GR++ + G Sbjct: 495 RLIFYTNSGTIPDEAMISVV-TENNRYVGNLEEEFVEILSPGDIFVLSGRTYEFIGSKGS 553 Query: 508 NLIIKVRESENIEGAIPSWEGELIPVPYEVAREVGRLRRTLLYDPRKAPDLIKGVEFNGE 567 +I+K E+ +PSW E++P+ YE A E+G+ RR + +K + +E + Sbjct: 554 KVIVK--EAMGQRPTVPSWFSEMLPLAYESALEIGKFRREIAEMIKKGVTHNEIIESISK 611 Query: 568 ELELALNS------------LKQNTLIPSDRDIIITVLPD-----TVIIHSDLGNKVNEG 610 E E+ ++ L N +PSD I+I + D I H+ G + + Sbjct: 612 EYEIDKHASMSIYTYILEQYLFTNGKVPSDNLILIEIYDDEEGIRNYIFHALYGRRALDA 671 Query: 611 ISR---YILGFLYSKYGRV-FTAKSQAHSIIIHAPFKMNPNEVKEILLKDYDTKTIISKT 666 +SR Y++ RV T A S+ PF N + E + D + I+++ Sbjct: 672 LSRAFAYVVSEELDTDVRVSVTDNGFALSVKRDVPFDYNIKSLFEKITPD-NVYDIVTRA 730 Query: 667 IRDSTVYRWKMINVAKRMGALSKRARIRNV--------QKLFEGTIIEV-------ETLN 711 + + + + + + A+R + +R + R ++ I E+ ET+ Sbjct: 731 VMRTEMLKRRFRHCAERSFMILRRYKGRETNLERRELNSEILLKAIREIGNFPVMKETIR 790 Query: 712 EVFHDKVDVQKVEEVLKLIAKGEIRI 737 E+ D +D+ + +E+LK IA EI++ Sbjct: 791 EILEDHMDILRAKEILKKIASQEIKV 816 >sp|P95949|HELX_SULSO PUTATIVE ATP-DEPENDENT HELICASE C04010 >gi|7446117|pir||S75377 probable helicase LHR - Sulfolobus solfataricus >gi|1707782|emb|CAA69580.1| (Y08257) ATP-dependent helicase [Sulfolobus solfataricus] Length = 875 Score = 315 bits (799), Expect = 1e-84 Identities = 237/806 (29%), Positives = 405/806 (49%), Gaps = 86/806 (10%) Query: 7 KAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDG-----LP 61 K ++K+ Q A I + +VL+ +PTGSGKT AA L +++S+ + G Sbjct: 22 KWFRQKYTTFTPPQRAAIPLIKQNYNVLVSSPTGSGKTLAAFLGILDSLFELGDNNELED 81 Query: 62 PISCLYIAPLKALNRDL-------LERLKWWEAKT-GIRIDVRHGDTTQYRRAKQVRNPP 113 + +YI+PL+ALN D+ L L+ +K +R+ +R DTT Y + K ++ PP Sbjct: 82 KVYAIYISPLRALNNDMQRNLLEPLNELRQVNSKLPDVRVGIRTSDTTPYEKQKMLKKPP 141 Query: 114 HVLITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNL---KRLSLIA 170 H+LITTPE+ +T L +V++++VDE+ EL ++KRGA L L + L Sbjct: 142 HILITTPESFGISITSPKFSQKLTDVKWIIVDEIHELANSKRGAYLSAMLELFRNLITKK 201 Query: 171 DFIRIGLSATVGNEEEVKEWL-GVDE---IVKPPLKKRYKFKVLFPRPRPEDKELAELLR 226 +F+RIGLSATV EEV ++L G D IV K KV+ P K+L Sbjct: 202 EFVRIGLSATVSPLEEVAQFLVGKDREYRIVDARFVKPVDIKVISPV-----KDLVHSSE 256 Query: 227 VDVEVAARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGK--------PVEVHHGS 278 +V+ +T+ V+KH+ L+F NTR E +A++L+ + +E HH S Sbjct: 257 SEVDKGI-YKTILNEVKKHRTTLIFTNTRHATERVAYKLRKLAENEKVFDVDAIEAHHSS 315 Query: 279 LSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKH 338 LS++ R++ E KLK+G +K ++ ++S+ELGIDIG +D VI SP+ V+RL+QR GR+ H Sbjct: 316 LSRDVRLDVEEKLKKGILKVVVSSTSLELGIDIGYIDLVILLSSPKSVSRLLQRIGRAGH 375 Query: 339 RLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIKPYENALDVLAHFIVGLLIEYQKL 398 + +S+ +I +D ++ ++AK A + K++ I +N LDVL+ IV + + Sbjct: 376 HIRSISKGRVIVVDRDDLVECSVLAKLARDRKIDSIHIPKNPLDVLSQIIVSASL-ISPI 434 Query: 399 NVHEPYRMAKETYPYRNLKWEHYLEVINVLED-----------AGIIRREEGILKLGRRA 447 + + +++ + +Y + +L Y V+ L A I +EE I+ + + Sbjct: 435 DRDDLFKILRRSYNFSDLSESDYSLVLRYLSGDFFGVELKNVYAKIRIKEEKIIYPKKGS 494 Query: 448 FKYYFDNLSTIPDEVSYKVVDIGSGKVIGRLDENFVMDLEEGMEFIMHGRSWLVLEIDGE 507 ++ N TIPDE VV + + +G L+E FV L G F++ GR++ + G Sbjct: 495 RLIFYTNSGTIPDEAMISVV-TENNRYVGNLEEEFVEILSPGDIFVLSGRTYEFIGSKGS 553 Query: 508 NLIIKVRESENIEGAIPSWEGELIPVPYEVAREVGRLRRTLLYDPRKAPDLIKGVEFNGE 567 +I+K E+ +PSW E++P+ YE A E+G+ RR + +K + +E + Sbjct: 554 KVIVK--EAMGQRPTVPSWFSEMLPLAYESALEIGKFRREIAEMIKKGVTHNEIIESISK 611 Query: 568 ELELALNS------------LKQNTLIPSDRDIIITVLPD-----TVIIHSDLGNKVNEG 610 E E+ ++ L N +PSD I+I + D I H+ G + + Sbjct: 612 EYEIDKHASMSIYTYILEQYLFTNGKVPSDNLILIEIYDDEEGIRNYIFHALYGRRALDA 671 Query: 611 ISR---YILGFLYSKYGRV-FTAKSQAHSIIIHAPFKMNPNEVKEILLKDYDTKTIISKT 666 +SR Y++ RV T A S+ PF N + E + D + I+++ Sbjct: 672 LSRAFAYVVSEELDTDVRVSVTDNGFALSVKRDVPFDYNIKSLFEKITPD-NVYDIVTRA 730 Query: 667 IRDSTVYRWKMINVAKRMGALSKRARIRNV--------QKLFEGTIIEV-------ETLN 711 + + + + + + A+R + +R + R ++ I E+ ET+ Sbjct: 731 VMRTEMLKRRFRHCAERSFMILRRYKGRETNLERRELNSEILLKAIREIGNFPVMKETIR 790 Query: 712 EVFHDKVDVQKVEEVLKLIAKGEIRI 737 E+ D +D+ + +E+LK IA EI++ Sbjct: 791 EILEDHMDILRAKEILKKIASQEIKV 816 >pir||A69140 ATP-dependent helicase - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621366|gb|AAB84818.1| (AE000816) ATP-dependent helicase [Methanobacterium thermoautotrophicum] Length = 702 Score = 262 bits (662), Expect = 1e-68 Identities = 175/542 (32%), Positives = 279/542 (51%), Gaps = 38/542 (7%) Query: 13 FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLK 72 +R L +Q A + I G+ LI+APT SGKTEAA++PV NSIL +GLPP+S LY++PLK Sbjct: 20 WRSLRDVQKSALEAIGRGEDTLIVAPTASGKTEAALIPVFNSILSEGLPPVSMLYVSPLK 79 Query: 73 ALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKS- 131 AL D+ RL+ W + + HGD R+ + ++NP +L+ TPE+L ++ +S Sbjct: 80 ALINDMHSRLELWGNHFNLEVMKWHGDVPANRKRRFIKNPSDILLITPESLEVMMINRSR 139 Query: 132 --LRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADF--IRIGLSATVGNEEEV 187 L N+R+++VDE+ + I+ RG QL L RL RIGLSATVGN EEV Sbjct: 140 AEKERILGNLRYIIVDEIHQFIEADRGVQLNSLLARLERYTGVRPQRIGLSATVGNPEEV 199 Query: 188 KEWLGVD-EIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEKHK 246 W+ +V+ +++ ++++ +L E+LR K Sbjct: 200 LNWMSPSGAVVRDTAERKLQYRIF----ELNHHKLIEVLRRFT---------------GK 240 Query: 247 RVLVFVNTRQFAEVLAHRL-KTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSM 305 +VL+FV +R+ AE + + K V +HH S+++++R EAE + + ++ TS++ Sbjct: 241 KVLIFVPSRRDAEKYYNIIRKCLDVDVFIHHSSINRDSREEAEERFRSVSAAFMVNTSTL 300 Query: 306 ELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKR 365 ELGID+G++D VI SP VNR +QR GRS R I ++ L +L +A Sbjct: 301 ELGIDVGDIDVVIHIRSPTSVNRFLQRTGRSGRRR---GLQRTIIFQEKEALTALSVASL 357 Query: 366 AIEGKLERIKPYENALDVLAHFIVGLLIEYQKLNVHEPYRMAKETYPYRNLKWEHYLEVI 425 A+ G+LE ++ LD+ H I+ + E +K + YR + + +L + + ++ Sbjct: 358 ALSGRLEDLRIPVRPLDIYFHQILSSVFELEKPTPGDIYRGLGRAHVFSDLDADDFRHLV 417 Query: 426 NVLEDAGIIRREEGILKLGRRAFK-----YYFDNLSTIPDEVSYKVVDIGSGKVIGRLDE 480 + + +R + G K + + + P + V KVIG LD Sbjct: 418 EFMVENDFLRVHGPYIHHGFNFEKTFGKMNFLEFYTVFPPNYEFTVKH--RTKVIGSLDS 475 Query: 481 NFVMD-LEEGMEFIMHGRSWLVLEIDGENLIIKVRESENIEGAIPSWEGELIPVPYEVAR 539 FV+ L+ G FI+ G W+V +ID E I++V+ + IP W P +EVAR Sbjct: 476 FFVVTYLKVGRGFILGGEKWVVKDIDHERFIVRVKPCTR-DAEIPDWSSGGAPTTFEVAR 534 Query: 540 EV 541 V Sbjct: 535 HV 536 >pir||F83237 probable ATP-dependent DNA helicase PA3272 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9949397|gb|AAG06660.1|AE004749_9 (AE004749) probable ATP-dependent DNA helicase [Pseudomonas aeruginosa] Length = 1448 Score = 257 bits (649), Expect = 5e-67 Identities = 197/592 (33%), Positives = 303/592 (50%), Gaps = 56/592 (9%) Query: 2 HILLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLP 61 H ++++ + F Q+EA+ I EG S L+ APTGSGKT A L +++++ +GL Sbjct: 22 HPVVRQWFERHFAAPTPAQVEAWPAIREGLSTLVAAPTGSGKTLTAFLAAIDALVVEGLA 81 Query: 62 P-------ISCLYIAPLKALNRDL-------LERLKWWEAKTG-----IRIDVRHGDTTQ 102 +Y++PLKAL+ D+ L ++ A+ G IR VR GDT Q Sbjct: 82 AGGELADATQVVYVSPLKALSNDIRINLEQPLAGIREELARLGLPDVDIRSAVRTGDTPQ 141 Query: 103 YRRAKQVRNPPHVLITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILN 162 R + PPH+L+TTPE+L LL +S R L VR V+VDE+ L +KRG+ L L+ Sbjct: 142 VERGAMRKRPPHILVTTPESLYILLGSESGRQMLAGVRSVIVDEIHALAGSKRGSHLALS 201 Query: 163 LKRLSLIAD--FIRIGLSATVGNEEEVKEWL-GVDEIVKPPLKKRYKFKVLFPRPRPEDK 219 L+RL + +RIGLSAT E+V +L G + P + V + RPR Sbjct: 202 LERLQALCPRPLLRIGLSATQKPIEKVARFLVGASGNPRDPACRIVD--VGYTRPRDLGI 259 Query: 220 ELAELLRVDVEVAARLRTLWEIVE--------KHKRVLVFVNTRQFAE----VLAHRLKT 267 E+ V +E A WE+V +H+ LVFVNTR+ AE LA RL + Sbjct: 260 EVPP---VALE-AVMSNDTWELVYDRLAHLAGEHRTTLVFVNTRRMAERVTRFLAERLGS 315 Query: 268 WGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVN 327 + V HHGSL+KE R++AE++LK G++K L+ T+S+ELGIDIG+V+ V Q SPR + Sbjct: 316 --RQVAAHHGSLAKELRLDAEQRLKAGQLKVLVATASLELGIDIGDVELVCQLSSPRSIA 373 Query: 328 RLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIKPYENALDVLAHF 387 +QR GRS H + + + T +D ++ + G+L+ + LDVLA Sbjct: 374 AFLQRVGRSGHSVGGTPKGRLFPTSRDDLVECAALLDSVRRGELDSLVLPRQPLDVLAQQ 433 Query: 388 IVGLLIEYQKLNVHEPYRMAKETYPYRNLKWEHYLEVINVLED---------AGIIRRE- 437 IV + Q+ + YR+ PY L+ E + EV+ +L + + R+ Sbjct: 434 IVA-EVACQEWREDDLYRLVIRAEPYAGLERERFDEVLRMLAEGYHSRLGVRGAYLHRDA 492 Query: 438 -EGILKLGRRAFKYYFDNLSTIPDEVSYKVVDIGSGKVIGRLDENFVMDLEEGMEFIMHG 496 G+L+ R A + TIPD Y V+ G ++G ++E+F ++ G F + Sbjct: 493 LNGLLRGRRGARLTALTSGGTIPDTGDYSVLLEPQGLLVGTVNEDFAVESLAGDVFQLGN 552 Query: 497 RSWLVLEIDGENLIIKVRESENIEGAIPSWEGELIPVPYEVAREVGRLRRTL 548 S+ ++ I+ ++V +++ IP W GE E++ V RLR TL Sbjct: 553 TSYRIIRIEPGR--VRVEDAQGQPPNIPFWLGEAPGRSDELSASVARLRDTL 602 >sp|P30015|LHR_ECOLI PROBABLE ATP-DEPENDENT HELICASE LHR (LARGE HELICASE-RELATED PROTEIN) >gi|7466703|pir||G64922 probable ATP-dependent helicase lhr (EC 3.6.1.-) - Escherichia coli >gi|993028|gb|AAC37009.1| (L01622) RNA helicase-like protein [Escherichia coli] >gi|1742726|dbj|BAA15419.1| (D90809) Probable ATP-dependent helicase Lhr (EC 3.6.1.-) (Large helicase- related protein). [Escherichia coli] >gi|1787942|gb|AAC74725.1| (AE000260) member of ATP-dependent helicase superfamily II [Escherichia coli K12] Length = 1538 Score = 249 bits (628), Expect = 1e-64 Identities = 226/844 (26%), Positives = 370/844 (43%), Gaps = 132/844 (15%) Query: 13 FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDG---------LPPI 63 F++ +Q + + + + L+IAPTGSGKT AA L ++ + ++G Sbjct: 27 FKQPTAVQPQTWHVAARSEHALVIAPTGSGKTLAAFLYALDRLFREGGEDTREAHKRKTS 86 Query: 64 SCLYIAPLKALNRDLL------------ERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRN 111 LYI+P+KAL D+ ER + E + +R+ +R GDT R+K RN Sbjct: 87 RILYISPIKALGTDVQRNLQIPLKGIADERRRRGETEVNLRVGIRTGDTPAQERSKLTRN 146 Query: 112 PPHVLITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLS--LI 169 PP +LITTPE+L +LT ++ R L+ V V++DEV + +KRGA L L+L+RL L Sbjct: 147 PPDILITTPESLYLMLTSRA-RETLRGVETVIIDEVHAVAGSKRGAHLALSLERLDALLH 205 Query: 170 ADFIRIGLSATVGNEEEVKEWLGVDE---IVKPPLKKRYKFKVLFPRPRPEDKELAELLR 226 RIGLSATV + +V +LG D +V PP + + +++ P +D Sbjct: 206 TSAQRIGLSATVRSASDVAAFLGGDRPVTVVNPPAMRHPQIRIVVPVANMDDVSSVASGT 265 Query: 227 VDVEVAARLRTLWEIVE--------KHKRVLVFVNTRQFAEVLAHRL------------- 265 + A R ++W +E +H+ +VF N+R AE L RL Sbjct: 266 GEDSHAGREGSIWPYIETGILDEVLRHRSTIVFTNSRGLAEKLTARLNELYAARLQRSPS 325 Query: 266 ---------KTWGKP-----------VEVHHGSLSKEARIEAERKLKEGKVKALICTSSM 305 T G HHGS+SKE R E+ LK G+++ ++ TSS+ Sbjct: 326 IAVDAAHFESTSGATSNRVQSSDVFIARSHHGSVSKEQRAITEQALKSGELRCVVATSSL 385 Query: 306 ELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKR 365 ELGID+G VD VIQ +P V +QR GR+ H++ VS+ D + S +I + Sbjct: 386 ELGIDMGAVDLVIQVATPLSVASGLQRIGRAGHQVGGVSKGLFFPRTRRDLVDSAVIVEC 445 Query: 366 AIEGKLERIKPYENALDVLAHFIVGLLIEYQKLNVHEPYRMAKETYPYRNLK---WEHYL 422 G+LE + P N LDVLA V L V E Y + P+++L ++ L Sbjct: 446 MFAGRLENLTPPHNPLDVLAQQTVA-AAAMDALQVDEWYSRVRRAAPWKDLPRRVFDATL 504 Query: 423 EVINVLEDAG---------IIRREEGILKLGRRAFKYYFDNLSTIPDEVSYKVV-----D 468 ++++ +G + RE GIL A + TIPD Y V+ + Sbjct: 505 DMLSGRYPSGDFSAFRPKLVWNRETGILTARPGAQLLAVTSGGTIPDRGMYSVLLPEGEE 564 Query: 469 IGSGKVIGRLDENFVMDLEEGMEFIMHGRSWLVLEIDGENLIIKVRESENIEGAIPSWEG 528 + +G LDE V + + SW + +I + +I V + +P W G Sbjct: 565 KAGSRRVGELDEEMVYESRVNDIITLGATSWRIQQITRDQVI--VTPAPGRSARLPFWRG 622 Query: 529 ELIPVPYEVAREVGRLRRTLLYDPRKAPDLIKGVEFNG-------EELELA----LNSLK 577 E P E+ +G L G F+G EE +A L + Sbjct: 623 EGNGRPAELGEMIGDFLHL----------LADGAFFSGTIPPWLAEENTIANIQGLIEEQ 672 Query: 578 QNT--LIPSDRDIIITVLPD-----TVIIHSDLGNKVNEGISRYILGFLYSKYGRVFTAK 630 +N ++P R +++ D +I+HS G +V+E + I G +++ +G + Sbjct: 673 RNATGIVPGSRHLVLERCRDEIGDWRIILHSPYGRRVHEPWAVAIAGRIHALWGADASVV 732 Query: 631 SQAHSIIIHAP-----------FKMNPNEVKEILLKDYDTKTIISKTIRDSTVYRWKM-- 677 + I+ P F P ++ +I+ + + + + R+ M Sbjct: 733 ASDDGIVARIPDTDGKLPDAAIFLFEPEKLLQIVREAVGSSALFAARFRECAARALLMPG 792 Query: 678 INVAKRMGALSKRARIRNVQKLFEG---TIIEVETLNEVFHDKVDVQKVEEVLKLIAKGE 734 R +R R + ++ +G + +ETL E D D+ +E +++ + GE Sbjct: 793 RTPGHRTPLWQQRLRASQLLEIAQGYPDFPVILETLRECLQDVYDLPALERLMRRLNGGE 852 Query: 735 IRIT 738 I+I+ Sbjct: 853 IQIS 856 >pir||A70982 probable ATP-dependent helicase lhr - Mycobacterium tuberculosis (strain H37RV) >gi|1877351|emb|CAB07060.1| (Z92771) lhr [Mycobacterium tuberculosis] Length = 1513 Score = 238 bits (600), Expect = 3e-61 Identities = 232/824 (28%), Positives = 370/824 (44%), Gaps = 121/824 (14%) Query: 20 QIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPIS-------CLYIAPLK 72 Q A+ I++G + L+IAPTGSGKT AA L ++S+ G P+S LY++PLK Sbjct: 31 QASAWAAIADGDNTLVIAPTGSGKTLAAFLWALDSLA--GSEPMSERPAATRVLYVSPLK 88 Query: 73 ALNRDLLERLKWWEA------------KTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTP 120 AL D+ L+ A IR+ VR GDT R + V PP VLITTP Sbjct: 89 ALAVDVERNLRTPLAGLTRLAERQGLPAPQIRVGVRSGDTPPALRRQLVSQPPDVLITTP 148 Query: 121 ETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIAD---FIRIGL 177 E+L +LT + R L V+ V++DE+ + KRGA L L+L+RL ++ RIGL Sbjct: 149 ESLFLMLT-SAARQTLTGVQTVIIDEIHAIAATKRGAHLALSLERLDDLSSRRRAQRIGL 207 Query: 178 SATVGNEEEVKEWLGVDE---IVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDV--EVA 232 SATV EE+ +L IV PP K + V P P ++A L + +V Sbjct: 208 SATVRPPEELARFLSGQSPTTIVAPPAAKTVELSVQVPVP-----DMANLTDNTIWPDVE 262 Query: 233 ARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRL--------------------------- 265 ARL +++E H +VF N+R+ AE L RL Sbjct: 263 ARLV---DLIESHNSTIVFANSRRLAERLTARLNEIHAARCGIELAPDTNQQVAGGAPAH 319 Query: 266 -----KTWGKP---VEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAV 317 +T+G P HHGS+SKE R E LK G++KA++ TSS+ELGID+G VD V Sbjct: 320 IMGSGQTFGAPPVLARAHHGSISKEQRAVVEEDLKRGQLKAVVATSSLELGIDMGAVDLV 379 Query: 318 IQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIKPY 377 IQ +P V +QR GR+ H++ E+S + D L + +R + G++E ++ Sbjct: 380 IQVQAPPSVASGLQRIGRAGHQVGEISRGVLFPKHRTDLLGCAVSVQRMLAGEIETMRVP 439 Query: 378 ENALDVLA-HFIVGLLIEYQKLNVHEPYRMAKETYPYRNLK---WEHYLEVIN------- 426 N LD+LA H + +E L+ + + P+ L +E L++++ Sbjct: 440 ANPLDILAQHTVAAAALE--PLDADAWFDTVRRAAPFATLPRSLFEATLDLLSGKYPSTE 497 Query: 427 --VLEDAGIIRREEGILKLGRRAFKYYFDNLSTIPDEVSYKV-VDIGSGKVIGRLDENFV 483 L + R+ G L A + + IPD + V + +G LDE V Sbjct: 498 FAELRPRLVYDRDTGTLTARPGAQRLAVTSGGAIPDRGLFAVYLATERPSRVGELDEEMV 557 Query: 484 MDLEEGMEFIMHGRSWLVLEIDGENLIIKVRESENIEGAIPSWEGELIPVPYEVAREVGR 543 + G + SW + EI + +++ + +P W G+ P E+ +G Sbjct: 558 YESRPGDVISLGATSWRITEITHDRVLVIPAPGQ--PARLPFWRGDDAGRPAELGAALGA 615 Query: 544 LRRTLLYDPRKA-PDLIKGVEFNG---EELELALNSLKQNT-LIPSDRDIIITVLPD--- 595 L L R A G+ F+ + L L+ + T ++P+D +++ D Sbjct: 616 LTGELAALDRTAFGTRCAGLGFDDYATDNLWRLLDDQRTATAVVPTDSTLLVERFRDELG 675 Query: 596 --TVIIHSDLGNKVNEGISRYILGFLYSKYGRVFTAKSQAHSIIIHAPFKMNPNEVK--- 650 VI+HS G +V+ ++ + L +YG + + I++ P ++ E Sbjct: 676 DWRVILHSPYGLRVHGPLALAVGRRLRDRYGIDEKPTASDNGIVVRLPDTVSAGEDSPPG 735 Query: 651 -EILLKDYD-TKTIISKTIRDSTVYRWKMINVAKRMGALSKR---------------ARI 693 E+ + D D I++ + S ++ + A R L +R AR+ Sbjct: 736 AELFVFDADEIDPIVTTEVAGSALFASRFRESAARALLLPRRHPGRRSPLWQQRQRAARL 795 Query: 694 RNVQKLFEGTIIEVETLNEVFHDKVDVQKVEEVLKLIAKGEIRI 737 V + + I +ET+ E D DV + E++ IA+ +R+ Sbjct: 796 LEVARKYPDFPIVLETVRECLQDVYDVPILVELMARIAQRRVRV 839 >pir||T35694 ATP dependent DNA helicase - Streptomyces coelicolor >gi|3294249|emb|CAA19862.1| (AL031031) ATP dependent DNA helicase [Streptomyces coelicolor A3(2)] Length = 1690 Score = 233 bits (589), Expect = 5e-60 Identities = 207/712 (29%), Positives = 323/712 (45%), Gaps = 99/712 (13%) Query: 20 QIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP-----ISCLYIAPLKAL 74 Q A++ IS+G VL++APTGSGKT AA L ++ + P LY++PLKAL Sbjct: 31 QAGAWQAISQGSDVLVVAPTGSGKTLAAFLAALDQLTSTPPPADPKKRCRVLYVSPLKAL 90 Query: 75 NRDLLERLKWWEAKTGIR--------------IDVRHGDTTQYRRAKQVRNPPHVLITTP 120 D+ L+ TGIR + +R GDT R PP +LITTP Sbjct: 91 AVDVERNLR--SPLTGIRQESVRLGLPEPEVKVGIRSGDTPAAERRALSTRPPDILITTP 148 Query: 121 ETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLS--LIADFIRIGLS 178 E+L +LT + R L + V++DEV + KRGA L L L+RL L RIGLS Sbjct: 149 ESLFLMLT-SATRDALTGIETVILDEVHAVAGTKRGAHLALTLERLDELLPKPARRIGLS 207 Query: 179 ATVGNEEEVKEWL---GVDEIVKPPLKKRYKFKVLFP---------RPRPEDKELAELLR 226 ATV +EV +L G EIV+P K + V+ P P E E AE Sbjct: 208 ATVRPVDEVARFLAPRGRVEIVQPESGKEFDLSVVVPVEDLGELGGSPVAEGNEGAERPS 267 Query: 227 VDVEVAARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRL------KTWGKPVE------- 273 + V R+ ++V+ H+ +VF N+R+ AE L +RL + G+P++ Sbjct: 268 IWPHVEERIT---DLVQSHRSTIVFANSRRLAERLCNRLNEIAYERATGEPLDEHHSPAE 324 Query: 274 -----------------VHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDA 316 HHGS+SKE R E LK G++ A++ TSS+ELGID+G VD Sbjct: 325 LMGGSGAAQGAPPVIARAHHGSVSKEQRALVEEDLKAGRLPAVVATSSLELGIDMGAVDL 384 Query: 317 VIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIKP 376 V+Q SP V +QR GR+ H++ VS + D +QS ++ +R G +E ++ Sbjct: 385 VVQVESPPSVASGLQRVGRAGHQVGAVSTGVVFPKYRGDLVQSAVVTERMRSGAIEALRI 444 Query: 377 YENALDVLAHFIVGLLIEYQKLNVHEPYRMAKETYPYRNLKWEHYLEVINVL-----EDA 431 N LDVLA +V + V + + P+ +L + V+++L DA Sbjct: 445 PANPLDVLAQQLVA-MTALDTWQVDDLLTTVRRAAPFASLPESAFTAVLDMLAGRYPSDA 503 Query: 432 -------GIIRREEGILKLGRRAFKYYFDNLSTIPDEVSYKVVDIGS-----GKVIGRLD 479 + R G + A + + TIPD + V G+ G +G LD Sbjct: 504 FAELRPRVVWDRVAGTVTGRPGAQRLAVTSGGTIPDRGLFGVFLAGADPKKGGGRVGELD 563 Query: 480 ENFVMDLEEGMEFIMHGRSWLVLEIDGENLIIKVRESENIEGAIPSWEGELIPVPYEVAR 539 E V + G F + SW + +I + ++ V + + G +P W+G+ + P E+ R Sbjct: 564 EEMVYESRVGDVFTLGTSSWRIEDITRDRVL--VSPAPGVPGRLPFWKGDQLGRPLELGR 621 Query: 540 EVGRLRR---TLLYDPRKAPDLIKGVEFNGEELELALNSLKQNTL--IPSDRDIIITVLP 594 +G R +L + + + G++ + L+ ++ +P DR I++ Sbjct: 622 ALGAFLREVGSLSKEDARLRLVTAGLDAWAADNVLSYLDEQREACGHVPDDRTIVVERFR 681 Query: 595 D-----TVIIHSDLGNKVNEGISRYILGFLYSKYGRVFTAKSQAHSIIIHAP 641 D V++HS G +V+ + + L +YG I++ P Sbjct: 682 DELGDWRVVVHSPFGAQVHAPWALALGARLSERYGMDAQVMHADDGIVLRLP 733 >pir||G71051 probable ATP-dependent helicase LHR - Pyrococcus horikoshii >gi|3257526|dbj|BAA30209.1| (AP000005) 1352aa long hypothetical ATP-dependent helicase LHR [Pyrococcus horikoshii] Length = 1352 Score = 194 bits (487), Expect = 5e-48 Identities = 127/334 (38%), Positives = 187/334 (55%), Gaps = 42/334 (12%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLP-- 61 L+++ K KF Q A I +G++VLI +PTGSGKT +A L +++ ++ G Sbjct: 24 LVREWFKRKFNSFTPPQRYAIVEIHKGENVLISSPTGSGKTLSAFLAIISELISLGRKGK 83 Query: 62 ---PISCLYIAPLKALNRDL-------LERLKWWEAKTG-----IRIDVRHGDTTQYRRA 106 I C+YI+PL+ALN D+ L +K + G IRI VR DT+ Y ++ Sbjct: 84 LEDKIYCVYISPLRALNNDIRRNLEEPLREIKELAQELGEEIPEIRIAVRTSDTSSYEKS 143 Query: 107 KQVRNPPHVLITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRL 166 K V+ PPH+LITTPE+L L R L++VR+V+VDEV L +NKRG+ L L L+RL Sbjct: 144 KMVKKPPHILITTPESLAIALNAPKFRERLRDVRWVIVDEVHALAENKRGSHLALTLERL 203 Query: 167 SLIA--DFIRIGLSATVGNEEEVKEWL-GVDE--------IVKPPLKKRYKFKVLFPRPR 215 + DF+RIGLSAT+ EEV +++ G ++ IV K+ + KV Sbjct: 204 RELVGRDFVRIGLSATIHPLEEVAKFVFGFNDDGTPRSGLIVDVSFAKQTEIKV------ 257 Query: 216 PEDKELAELLRVDVEVA--ARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRLK----TWG 269 + + +L+ D E A L E++ KHK L+F NTR AE +A LK + Sbjct: 258 --ESVVEDLIYTDAETLSNALYNRLAELIRKHKTTLIFTNTRSGAERVAFNLKKRFPEFK 315 Query: 270 KPVEVHHGSLSKEARIEAERKLKEGKVKALICTS 303 +E HH SLS+E R++ E KLK G+++A++C S Sbjct: 316 GLIETHHSSLSREVRLDVEEKLKRGELRAVVCVS 349 Score = 170 bits (427), Expect = 5e-41 Identities = 165/640 (25%), Positives = 296/640 (45%), Gaps = 74/640 (11%) Query: 188 KEWLGVDEIVKPPLKKRYK-------FKVLFPRPRPEDKELAELLRVDVEVAARLRTLWE 240 KEW E V P L+KR K + + R EL ++++ E AR R L + Sbjct: 715 KEW----EDVIPNLEKRLKEIEEKLGYPGTYNRREIRRSELKAIIKL-YEKVARERGLND 769 Query: 241 IVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPV--EVHHGSLSKEARIEAERKLKEGKVKA 298 ++++ L ++ ++ R+ T +PV +V +G ++ E + G V Sbjct: 770 VLKE----LSYLKELSEGDIFFDRI-TSIEPVYLDVAYGIINSETG----NYVVNGFVSK 820 Query: 299 LICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQ 358 TS +ELGIDIG +D V+ SP+ VNR +QR GR+ HRL EVS I+A +D ++ Sbjct: 821 NSSTS-LELGIDIGTIDLVVLVGSPKSVNRALQRIGRAGHRLHEVSRGIILALDRDDLVE 879 Query: 359 SLIIAKRAIEGKLERIKPYENALDVLAHFIVGLLIEYQKLNVHEPYRMAKETYPYRNLKW 418 ++A A KL+RIK +N LDVL I+G+ +E + + E YR+ + YPY L + Sbjct: 880 VTVLAHNARNRKLDRIKIPKNPLDVLVQHILGMALE-KVWEIEEAYRVVRRAYPYHELPF 938 Query: 419 EHYLEVINVL--EDAGI--------IRREEGILKLGRR---AFKYYFDNLSTIPDEVSYK 465 ++ V+ L E +G+ I E G K GRR Y+ N TIPDE Sbjct: 939 SDFMNVLKYLAGEYSGLEEKRVYAKIWLENG--KFGRRGKMTRAIYYMNTGTIPDEAKID 996 Query: 466 VVDIGSGKVIGRLDENFVMDLEEGMEFIMHGRSWLVLEIDGENLIIKVRESENIEGAIPS 525 V + K IG ++E F L G F++ GR++ ++ G + + R E + IPS Sbjct: 997 VFTLDK-KYIGTVEEEFAERLMPGDIFVLAGRTYEFVKSRGNKIYVIPR--EGAKPTIPS 1053 Query: 526 WEGELIPVPYEVAREVGRLR---RTLLYDPRKAPDLIKGVEFNGEELELALNSLKQN--- 579 W E++P+ +++A ++ R R + LL R L+K + + ++ ++ Sbjct: 1054 WFSEMLPLSFDLAIDIQRFRGEVKKLLTSKRAESLLMKKYGIDNVTAKAIISYFREQAKY 1113 Query: 580 TLIPSDRDIIITVLPD----TVIIHSDLGNKVNEGISRYILGFLYSKYGRV---FTAKSQ 632 ++IP D +++ ++ + H+ +G + N+ +SR ++ SK + Sbjct: 1114 SIIPDDETVLVEIVREGNVTKYFFHTLIGRRANDALSR-AFAYMISKKKKCNVGIAITDN 1172 Query: 633 AHSIIIHAPFKMNPNEVKEILLKDYDTKTIISKTIRDSTVYRWKMINVAKR----MGALS 688 + + ++ E+ E+ + + + I+ + + ++ + + + +VA R + Sbjct: 1173 GFMLKVPVDKELKEGEILELFYVE-NLREILKRALDNTELLKRRFRHVANRGLLILRRYM 1231 Query: 689 KRARIRNVQKLFEGTIIEV------------ETLNEVFHDKVDVQKVEEVLKLIAKGEIR 736 R + + Q++ T++ E E+ DK+D++ E LK I +G+I+ Sbjct: 1232 GREKSLSRQQMNAQTLLNFLKKNHPNFPLLKEVYREIMEDKMDIENAELFLKWIKEGKIK 1291 Query: 737 ITGRILNEPEEIDKEHGTISMEFMVSLHHTDEEIVELFKQ 776 +T R P I +V + E I EL K+ Sbjct: 1292 VTVREHPYPSPFAFNLEVIGASDVVLMEDRRELIKELHKK 1331 >pir||T35049 probable ATP-dependent helicase - Streptomyces coelicolor >gi|3483040|emb|CAA20551.1| (AL031371) putative ATP-dependent helicase [Streptomyces coelicolor A3(2)] Length = 731 Score = 187 bits (471), Expect = 4e-46 Identities = 162/550 (29%), Positives = 270/550 (48%), Gaps = 37/550 (6%) Query: 15 ELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLKAL 74 +L LQ A + EG+ +++APT GKTEAA P+++++ + S LY+ PLKAL Sbjct: 35 DLRPLQRAAITPLMEGEDAVLLAPTAGGKTEAACFPLLSAMAEQKWTGTSVLYLCPLKAL 94 Query: 75 NRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLT-VKSLR 133 +L+ R+ + G R + HGDT + +R + P VL+TTPE+L A+L VK+ Sbjct: 95 LNNLVSRVDTYTQWLGRRAALWHGDTKESQRQRIRTEAPDVLLTTPESLEAMLIGVKTDH 154 Query: 134 P-YLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIA--DFIRIGLSATVGNEEEVKEW 190 L +VR VVVDEV + RG L+ L+RL + RIGLSATVGN +++ +W Sbjct: 155 ARLLGSVRAVVVDEVHAFAGDDRGWHLLAVLERLEQVTGRPIQRIGLSATVGNPDQLLDW 214 Query: 191 L---GVD----EIVKPPLKKRYKFKVLFPRPRPEDKELAELL-RVDVEVAARLRTLWEIV 242 L GV+ +V P + F+ + +P +E+ V+++ L +++ Sbjct: 215 LQGAGVETRAGRVVAPGVTLP-AFEAVGSDRKPTAEEVPRPAGEVELDYVGSLDNAAKLI 273 Query: 243 ---EKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKAL 299 + ++ LVF ++R E L L+ V + H SLS + R +E+ E + + Sbjct: 274 ATLHRGEKRLVFCDSRAQVEQLGAALRAREVTVFLSHASLSVDERTRSEQAFAEARDCVI 333 Query: 300 ICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQS 359 + TS++ELGID+G++D VIQ SP V +QR GR+ R V + T + LQ+ Sbjct: 334 VSTSTLELGIDVGDLDRVIQIDSPATVASFLQRIGRTGRRAGTVRNCLFLTTRKDTLLQA 393 Query: 360 LIIAKRAIEGKLERIKPYENALDVLAHFIVGLLIEYQKLNVHEPYRMAKETYPYRNLKWE 419 + G +E +KP ++A ++ + ++ KL R P+ + Sbjct: 394 AGLLLLWSRGWVEPVKPPPEPRHLVAQQLLAVTLQQHKLGDQLWDRQWNGLAPFD----Q 449 Query: 420 HYLEVINVLEDAGIIRREEGILKLG----RRAFKYYFDNLS---TIPDEVSYKVVDIGSG 472 ++ L + G + + G+L +G RR K +F L+ T P + + + SG Sbjct: 450 SAAPILRHLTEEGFLDSDGGLLFVGPEAERRFGKRHFIELTASFTAPPQFT-----VLSG 504 Query: 473 KV-IGRLDENFVMDLEEG-MEFIMHGRSWLVLEIDGENLIIKVRESENIEGAIPSW-EGE 529 + IGR D + + + G ++ GRSW V ID + V +++ G I W G Sbjct: 505 RTEIGRTDPSVLTEERPGPRRLLLGGRSWQVTYIDWLRKRVFVEPADS--GGIAKWMNGG 562 Query: 530 LIPVPYEVAR 539 + + Y + R Sbjct: 563 IAGLTYALTR 572 >gb|AAK40384.1| ATP-dependent helicase [Sulfolobus solfataricus] Length = 739 Score = 145 bits (361), Expect = 3e-33 Identities = 106/341 (31%), Positives = 176/341 (51%), Gaps = 23/341 (6%) Query: 5 LKKAIKEK-FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LKK+I E L + Q +A+++I ++V+II+ TG+GKTEA ++P+++ LK Sbjct: 44 LKKSIIEYGIERLYKYQYDAYRKIKNKENVMIISGTGTGKTEAFLIPILDLALKGE---- 99 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 + + P KAL RD L R+ + G+ + + GDT + R + RNPPH+LIT P+ + Sbjct: 100 RSVLVYPTKALARDQLTRVYKLARELGLNVGIFDGDTPEKERERLYRNPPHILITNPDMI 159 Query: 124 PALLTVKS-LRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRI-GLSATV 181 L + + R L+ + DEV + + GA + R+ + I I SATV Sbjct: 160 HLGLALSTRFRFLLRTADHFIFDEV-HVYEGVLGAHIRNLADRIKEFKNDIHIVASSATV 218 Query: 182 GNEEEV-KEWLGVDEIVKPPLKKRYKFKV--LFPRPRPEDKELAELLRVDVEVAARLRTL 238 G + + +E GV+ + +++R + + LA L Sbjct: 219 GATKYLFEELFGVEGEIIEGIRRRKGIAIHSIIDSGNSSRWTLAAYLAA----------- 267 Query: 239 WEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKA 298 +V+ +VLVF +++Q AE++A + +EVH L E RI+ E KL+ G++ Sbjct: 268 -VLVKNGLKVLVFTDSQQMAELVAKIADRFRVNLEVHRAGLIAEERIKVEEKLRNGELDG 326 Query: 299 LICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHR 339 ++ T ++ELGIDIG +DAVI +P + +QRAGR+ R Sbjct: 327 VVATPTLELGIDIGTIDAVIMAENPPSYTKYVQRAGRAGRR 367 >gi|11499982 ATP-dependent RNA helicase, putative [Archaeoglobus fulgidus] >gi|7446072|pir||G69550 ATP-dependent RNA helicase homolog AF2406 - Archaeoglobus fulgidus >gi|2650686|gb|AAB91259.1| (AE001109) ATP-dependent RNA helicase, putative [Archaeoglobus fulgidus] Length = 766 Score = 125 bits (312), Expect = 2e-27 Identities = 98/328 (29%), Positives = 155/328 (46%), Gaps = 22/328 (6%) Query: 10 KEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIA 69 K L Q EA R+ EG+ V+I APTG GKTEA +P++ L G + Sbjct: 80 KRGIGRLYPFQKEAMIRLMEGRDVVITAPTGFGKTEAFAVPMLWRALHGG----KAMVFY 135 Query: 70 PLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPA-LLT 128 P KAL RD E++K++ + G+R GD+ + R + +++T P+ + L Sbjct: 136 PTKALARDQEEKIKFYTSSLGLRAVRFDGDSGREERRAVLSGKCDIILTNPDMVDYHLRN 195 Query: 129 VKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGNEEEVK 188 + R + + F+ VDE+ G+ + +KRLS A+F SAT+ N E Sbjct: 196 TPAFRRICRELSFIAVDEL-HTYTGVLGSNMHYLVKRLSRFAEFQIACASATLSNAAEFA 254 Query: 189 EWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEKHKRV 248 E L + V + R L R P L E+ LR ++++ Sbjct: 255 EELFDRDFVLVSGEHRKGTLHLIFRYTPS------LYSAVREIVTALR--------NRKI 300 Query: 249 LVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELG 308 +VF N+ + E + L+ G +H L KE R E E K K G++ ++ T ++ELG Sbjct: 301 IVFGNSYKSVETINLILRRHGLKSAIHKSGLPKEVREEVEAKFKRGEINIVVSTPTLELG 360 Query: 309 IDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 +DIG+VD V+ + P ++IQR GR+ Sbjct: 361 VDIGDVDVVVSELVP--YGQMIQRVGRA 386 >pir||E71073 hypothetical protein PH1280 - Pyrococcus horikoshii >gi|3257700|dbj|BAA30383.1| (AP000005) 715aa long hypothetical protein [Pyrococcus horikoshii] Length = 715 Score = 122 bits (304), Expect = 1e-26 Identities = 137/501 (27%), Positives = 227/501 (44%), Gaps = 66/501 (13%) Query: 5 LKKAIKEK-FRELNRLQIEAFKR-ISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP 62 +K+ +K++ EL Q EA I +G++ LI PT SGKT A + ++N +LK+G Sbjct: 12 IKEVLKKRGISELYPPQAEALTSGILKGENALIAIPTASGKTLIAEIAIVNRLLKEGGKA 71 Query: 63 ISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPET 122 + Y+ PLKAL + + K WE + G+++ + GD Y + ++I T E Sbjct: 72 V---YLVPLKALAEEKFKEFKDWE-ELGLKVAMATGD---YDSKDEWLGGYDIIIATAEK 124 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVG 182 +LL S +++NV+ +VVDE+ + RGA L + ++ A I GLSAT+G Sbjct: 125 FDSLLRHGS--SWIRNVKVLVVDEIHLIGSRDRGATLEFIITQMLNRAQII--GLSATIG 180 Query: 183 NEEEVKEWLGVDEIVKP--PLKKR----YKFKVLFPRPRPEDKELAELLRVD-------- 228 N EE+ EWL I P+K R Y+ V + + E E L D Sbjct: 181 NPEELAEWLNAKLIKSDWRPVKLRRGVFYQGFVFWEDGKTEKFNSWEELVYDAIKRSKGS 240 Query: 229 -VEVAARLRTLWEIVEKHKRVLVFVNTRQFAEV--LAHRL----------KTWGKPVEVH 275 V V R + +E K++ F+ ++ E+ LA L K V H Sbjct: 241 LVFVNMRRKAEKTALELSKKIRNFLTKKELRELKELAESLEENPTNEKLAKALQGGVAFH 300 Query: 276 HGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVI-----------QYMSPR 324 H L +E R+ E K+G +K ++ T ++ GI+ ++ + + Sbjct: 301 HAGLGREERVLVEENFKKGLIKVVVATPTLSAGINTPAFRVIVRDTWRYSEFGMERIPIL 360 Query: 325 QVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIKPYENALDVL 384 ++ +++ RAGR K+ EV EA I++T E + +R I+GK E++ + +L Sbjct: 361 EIQQMMGRAGRPKYD--EVGEAIIVSTTEE----PSTVMERYIKGKPEKLFSQLSNESIL 414 Query: 385 AHFIVGLLIEYQKLNVHEPYRMAKETYPYRNLKWEHYLE------VINVLEDAGI---IR 435 I+ L+ + + E Y + T+ K + LE V +LE+ I + Sbjct: 415 RGQILALIATFNFSSFREIYDFLERTFYAYQGKDPYTLEDRIRDIVYFLLENEFIEITLD 474 Query: 436 REEGILKLGRRAFKYYFDNLS 456 E L LG R K Y D ++ Sbjct: 475 DEIKALPLGIRTAKLYIDPMT 495 >pir||F69164 ATP-dependent RNA helicase homolog MTH492 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621563|gb|AAB84998.1| (AE000833) ATP-dependent RNA helicase, eIF-4A family [Methanobacterium thermoautotrophicum] Length = 822 Score = 119 bits (296), Expect = 1e-25 Identities = 142/530 (26%), Positives = 242/530 (44%), Gaps = 65/530 (12%) Query: 16 LNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLKALN 75 L R Q EA I EG ++LI PT SGKT A LP+M ++ + P + LYI P+KAL+ Sbjct: 53 LYRHQREALDAIREGMNILITTPTASGKTLAFNLPIMETLTLN--PDATALYIYPVKALS 110 Query: 76 RDLLERLKWWEAKTGIRID--VRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVK-SL 132 RD L L+ E++ G++++ GDT + RR +R V++T P L +L Sbjct: 111 RDQLGVLEELESELGLKLNPSTYDGDTPRERRP-WIRENSRVILTNPHQLHRILPWHHQW 169 Query: 133 RPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIR-----IGLSATVGNEEEV 187 R + N+R+VV+DE + G+ + L L+RL I + + SAT+ N E Sbjct: 170 RRFYSNLRYVVIDEAHQY-RGVFGSNVALLLRRLRRICRYYGSEPQFVLASATLANPAEF 228 Query: 188 KEWL-GVDEIVKPPLKKRYKFKVLFPRPRPEDKE---LAELLRVDVEVAARLRT---LWE 240 L G+D F+V+ P + L R + +A L T L Sbjct: 229 SRKLTGLD------------FRVISDDTSPSGPKHFILYNPYRKRGDPSAHLETSAILSY 276 Query: 241 IVEKHKRVLVFVNTRQFAEVLAH---------RLKTWGKPVEVHHGSLSKEARIEAERKL 291 +V + + L F +R+ AE++ K + G L+++ R E L Sbjct: 277 LVLRGVQTLCFTISRKMAELVTRWTREQLDRENRKLVDRVTSYRAGYLAEQRR-RIEADL 335 Query: 292 KEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIAT 351 KEG++ + T+++ELGIDIG +DAVI P + Q+AGR+ L ++ +I Sbjct: 336 KEGRLLGVTATNALELGIDIGSLDAVIISGYPGTMISTWQQAGRAGRNL---KDSMVILV 392 Query: 352 GVEDYLQSLIIAKRAIEGKLERIKPYENALDVLAHFIVGLLIEYQKLNVHEPYRMAKETY 411 E+ L I+ + + +P+ENA+ L + L++ Q + + + Sbjct: 393 AFENPLDQYIMKNPSFIFE----RPHENAIIDLQN---RLILRNQTACAASELPLILDDF 445 Query: 412 PYRNLKWEHYLEVI-NVLEDAGIIRREEGILKLGRRAFKYYFDNLSTIPDEVSYKVVDIG 470 L+++ + V +L D + +G+ G F+Y D++S V I Sbjct: 446 ----LEYDFSVGVAGEMLADGELELAPDGLTCSGDPQFRYGLDDVSQDTFTV------IC 495 Query: 471 SGKVIGRLDEN-FVMDLEEGMEFIMHGRSWLV--LEIDGENLIIKVRESE 517 G+V+ + + + EG + HG ++ V +++G +I+ R+ E Sbjct: 496 EGRVLETMSRSQAYREAHEGAVLMNHGNTYTVRDFDLEGRRIIVDRRDVE 545 >pir||F71092 ATP-dependent RNA helicase homolog PH1003 - Pyrococcus horikoshii >gi|3257417|dbj|BAA30100.1| (AP000004) 873aa long hypothetical helicase [Pyrococcus horikoshii] Length = 873 Score = 119 bits (295), Expect = 2e-25 Identities = 155/667 (23%), Positives = 294/667 (43%), Gaps = 125/667 (18%) Query: 10 KEKFRELNRL-----------QIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKD 58 K K RE+N L Q++A + GK+V++ PT SGK+E L + +S L++ Sbjct: 30 KFKNREVNELVKRLGFRLYSHQVKALNLLYSGKNVVVSTPTASGKSEIFRLFIFDSFLEN 89 Query: 59 GLPPISCLYIAPLKALNRDLLERL----KWWEAKTGIRI--DVRHGDTTQYRRAKQVRNP 112 P + L + P +AL + +E+ K + TG+++ + GD R K VRN Sbjct: 90 --PSSTFLLVYPTRALINNQMEKFDNENKVFAEITGMKVKASILTGDVDWSERKKIVRNK 147 Query: 113 PHVLITTPETL-----PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGA---------- 157 P+V+ TTP+ L P L K L LKN++ +VVDE + RG Sbjct: 148 PNVIFTTPDMLHHTILPRWLEYKWL---LKNLKLLVVDE----LHTYRGVFGSNVAYVFR 200 Query: 158 QLILNLKRLSLIADFIRIGLSATVGNEEEVKE---WLGVDEIVKPPLKKRYKFKVLFPRP 214 ++ L+RL+ + + + LSAT+ N +E E +E+ + ++ ++F Sbjct: 201 RVFFRLRRLN--SSPLILALSATLRNPKEFAESFFGFEFEEVTEAGNPSPRRYIIMFEPK 258 Query: 215 RPEDKELAELLRVDVEVAARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRL--KTWGKPV 272 R ++L + + + +++ + + LVF ++R+ E + + + Sbjct: 259 RFSGEQLIK------------QVIDKLIRNNVKTLVFFDSRKGTERIMRMFLFSEFFDKI 306 Query: 273 EVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQ-VNRLIQ 331 + G+L+K R + ER +EG +K L+ T+++ELGID+G++DAVI Y P + LIQ Sbjct: 307 TTYKGTLTKLERWKIERDFREGNLKVLLATNALELGIDVGDLDAVINYGIPSDGLFSLIQ 366 Query: 332 RAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIKPYENALDVLAHFIVGL 391 R GR+ V+ + +I+ K ++ Y+ D L I Sbjct: 367 RFGRAGRDPNRVA------------INGIILRKNGLD------YYYKEHFDELVEGIEKG 408 Query: 392 LIEYQKLNV--------HEPYRMAKETYPYRNLKWEHYLEVINVLEDAGIIRREEGIL-- 441 L++ +N+ H Y +++ ++ E++++V+ L+ GI+ + + Sbjct: 409 LVDKIPVNLGNEKIAKKHLHYLLSELGVVGKDEIPEYWVKVLEDLKHEGIVDEYKNPITG 468 Query: 442 KLGRRAFK-YYFDNLSTIPDEVSYKVVDIG-----------------------SGKVIGR 477 K R K + ++ T DE + V+D G G +I Sbjct: 469 KFEVRVRKPAVYSSIRTASDESFFLVIDEGWIRRTLRRKRGIELLRFINYLKARGLIIEE 528 Query: 478 LDE-NFVMDLEEGMEFIMHGRSWLV---LEIDGENLII--KVRESENIEGAIPSWEGELI 531 +DE F L GM + GR ++ L+++ N + ++ +E++E + E I Sbjct: 529 VDEVEFHRSLLPGMVYPSRGRLYMAVDRLKVEKFNFVFAREIPMNEDLETNVSKVESVEI 588 Query: 532 PVPYEVAREVGRLRRTLLYDPRKAPDLIKGVEFNGEELEL---ALNSLKQNTLIPSDRDI 588 YE + +G ++ + + + G G+++E L LK ++ + ++ Sbjct: 589 LNTYE-GKNIGPVK--VYFGRIRVKQEYNGYAVKGKDVEKHVDRLEKLKDEGILRGEVEV 645 Query: 589 IITVLPD 595 +T+ D Sbjct: 646 AVTMFED 652 >pir||B75135 DNA helicase related protein PAB0592 - Pyrococcus abyssi (strain Orsay) >gi|5458306|emb|CAB49795.1| (AJ248285) DNA HELICASE RELATED PROTEIN [Pyrococcus abyssi] Length = 715 Score = 117 bits (290), Expect = 6e-25 Identities = 135/513 (26%), Positives = 224/513 (43%), Gaps = 90/513 (17%) Query: 5 LKKAIKEK-FRELNRLQIEAFKR-ISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP 62 +K+ ++E+ EL Q EA + EG+++L+ PT SGKT A + + N +L++G Sbjct: 12 IKEILRERGIEELYPPQAEALTSGVLEGENLLVAIPTASGKTLIAEIAIANKLLEEG--- 68 Query: 63 ISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPET 122 +YI PLKAL + K WE + G+++ + GD Y + ++I T E Sbjct: 69 GKAVYIVPLKALAEEKFREFKDWE-RLGLKVAMATGD---YDSKDEWLGKYDIIIATAEK 124 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVG 182 +LL S ++++V+ +V+DE+ + RGA L + ++ A IGLSAT+G Sbjct: 125 FDSLLRHGS--SWIRDVKMLVIDEIHLIGSRDRGATLEFIITQMLGRAQI--IGLSATIG 180 Query: 183 NEEEVKEWLGVDEIVKP--PLKKR----YKFKVLFPRPRPEDKELAELLRVDVEVAARLR 236 N EE+ EWL I P+K R Y+ V + E E L Sbjct: 181 NPEELAEWLNAKLIRSDWRPVKLRKGVFYQGFVFWEDGGSERYNSWEEL----------- 229 Query: 237 TLWEIVEKHKRVLVFVNTRQFAEVLAHRL------------------------------- 265 +++ V+K K LVFVN R+ AE A L Sbjct: 230 -VYDAVKKGKGALVFVNMRRKAEKTALELAKKVKNYLDRKELRELRELAESLEENPTNEK 288 Query: 266 --KTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVI----- 318 K V HH L ++ R+ E ++G +K ++ T ++ GI+ +I Sbjct: 289 LAKALLSGVAFHHAGLGRDERVLVEDNFRKGLIKVVVATPTLSAGINTPAFRVIIRDTWR 348 Query: 319 ------QYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLE 372 + + +V +++ RAGR ++ EV EA I++T E L + I+GK E Sbjct: 349 YSEFGMERIPVLEVQQMMGRAGRPRYD--EVGEAIIVSTTEEPSL----VIDHYIKGKPE 402 Query: 373 RIKPYENALDVLAHFIVGLLIEYQKLNVHEPYRMAKETYPYRNLKWEHYLE------VIN 426 ++ + +L I+ L+ + E Y + T+ K + LE + Sbjct: 403 KLFSQLSNESILRSQILALIATFGYSEFKEIYDFLERTFYAHQGKDPYMLEEKIRRIIYF 462 Query: 427 VLEDAGI-IRREEGI--LKLGRRAFKYYFDNLS 456 +LE+ I + E+ I L LG R K Y D ++ Sbjct: 463 LLENEFIEVTLEDEIKPLPLGVRTTKLYIDPMT 495 >pir||T43854 helicase [imported] - Pyrococcus furiosus >gi|3374506|dbj|BAA32016.1| (AB016521) helicase [Pyrococcus furiosus] Length = 720 Score = 115 bits (284), Expect = 3e-24 Identities = 139/510 (27%), Positives = 222/510 (43%), Gaps = 90/510 (17%) Query: 5 LKKAIKEK-FRELNRLQIEAFKR-ISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP 62 +K +KE+ Q EA K I EGK+ LI PT SGKT A + +++ IL G Sbjct: 12 IKSTLKERGIESFYPPQAEALKSGILEGKNALISIPTASGKTLIAEIAMVHRILTQGGKA 71 Query: 63 ISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPET 122 + YI PLKAL + + + WE K G+R+ + GD Y + ++I T E Sbjct: 72 V---YIVPLKALAEEKFQEFQDWE-KIGLRVAMATGD---YDSKDEWLGKYDIIIATAEK 124 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVG 182 +LL S ++K+V+ +V DE+ + RGA L + L + A I GLSAT+G Sbjct: 125 FDSLLRHGS--SWIKDVKILVADEIHLIGSRDRGATLEVILAHMLGKAQII--GLSATIG 180 Query: 183 NEEEVKEWLGVDEIVKP--PLKKR----YKFKVLFPRPRPEDKELAELLRVDVEVAARLR 236 N EE+ EWL + IV P+K R Y+ V + ED + ++ Sbjct: 181 NPEELAEWLNAELIVSDWRPVKLRRGVFYQGFVTW-----EDGSIDRF-------SSWEE 228 Query: 237 TLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKP------------------------- 271 +++ + K K L+FVN R+ AE +A L K Sbjct: 229 LVYDAIRKKKGALIFVNMRRKAERVALELSKKVKSLLTKPEIRALNELADSLEENPTNEK 288 Query: 272 --------VEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVI----- 318 V HH L ++ R+ E ++G +KA++ T ++ GI+ +I Sbjct: 289 LAKAIRGGVAFHHAGLGRDERVLVEENFRKGIIKAVVATPTLSAGINTPAFRVIIRDIWR 348 Query: 319 ------QYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLE 372 + + +V++++ RAGR K+ EV E I++T +D + + I GK E Sbjct: 349 YSDFGMERIPIIEVHQMLGRAGRPKYD--EVGEGIIVSTS-DDPRE---VMNHYIFGKPE 402 Query: 373 RIKPYENALDVLAHFIVGLLIEYQKLNVHEPYRMAKETYPYRNLKWEHYLE------VIN 426 ++ + L ++ L+ + V E + T+ K + LE + Sbjct: 403 KLFSQLSNESNLRSQVLALIATFGYSTVEEILKFISNTFYAYQRKDTYSLEEKIRNILYF 462 Query: 427 VLEDAGI-IRREEGI--LKLGRRAFKYYFD 453 +LE+ I I E+ I L LG R K Y D Sbjct: 463 LLENEFIEISLEDKIRPLSLGIRTAKLYID 492 >sp|P50830|YPRA_BACSU HYPOTHETICAL HELICASE IN PONA-COTD INTERGENIC REGION >gi|7446091|pir||B69941 ATP-dependent RNA helicase homolog yprA - Bacillus subtilis >gi|1146178|gb|AAB38468.1| (L47838) helicase [Bacillus subtilis] >gi|2634641|emb|CAB14139.1| (Z99115) similar to ATP-dependent helicase [Bacillus subtilis] Length = 749 Score = 114 bits (282), Expect = 5e-24 Identities = 140/544 (25%), Positives = 241/544 (43%), Gaps = 77/544 (14%) Query: 10 KEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIA 69 K EL Q AF+ + +G+S++ + PT SGKT LPV+ SI +D LY+ Sbjct: 49 KRGIDELYTHQYSAFQYVQKGESIVTVTPTASGKTLCYNLPVLQSIAQDETN--RALYLF 106 Query: 70 PLKALNRDLLERLKWWEAKTGIRID--VRHGDTTQYRRAKQVRNPPHVLITTPETLPALL 127 P KAL +D L + GI I GDT+ R K VR H++IT P+ L + + Sbjct: 107 PTKALAQDQKSELNEIIDEMGIDIKSFTYDGDTSPAIRQK-VRKAGHIVITNPDMLHSAI 165 Query: 128 TVKSLR--PYLKNVRFVVVDEVTEL--IDNKRGAQLILNLKRLSLI--ADFIRIGLSATV 181 + +N++++V+DE+ + A +I LKR+ +D + I SAT+ Sbjct: 166 LPHHTKWVSLFENLKYIVIDELHTYRGVFGSHVANVIRRLKRICRFYGSDPVFICTSATI 225 Query: 182 GNEEEVKEWLG------VDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARL 235 N +E+ E L VD+ P +K + +F P +K L EV Sbjct: 226 ANPKELGEQLTGKPMRLVDDNGAPSGRKHF----VFYNPPIVNKPLNIRRSATAEVNELA 281 Query: 236 RTLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTW------GKPVEVHHGSLSKEARIEAER 289 + E ++ + +VF +R E++ ++ K + + G + R E ER Sbjct: 282 K---EFLKNKVQTIVFARSRVRVEIILSHIQELVKKEIGTKSIRGYRGGYLPKERREIER 338 Query: 290 KLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYII 349 L+EG + ++ T+++ELG+DIG++ + P V Q+AGR+ R E+ II Sbjct: 339 GLREGDILGVVSTNALELGVDIGQLQVCVMTGYPGSVASAWQQAGRAGRR---HGESLII 395 Query: 350 ----ATGVEDYL--QSLIIAKRAIEGKLERIKPYENALDVLAHFIVGLLIEYQKLNVHEP 403 +T ++ Y+ R+ E RI P EN + +L+++ K +E Sbjct: 396 MVANSTPIDQYIVRHPEYFFNRSPES--ARINP-ENLI---------ILVDHLKCAAYE- 442 Query: 404 YRMAKETYPYRNLKWEHYLEVINVLEDAGIIRREEGILKLGRRAFKYYFDNLSTIPDEVS 463 P+R + +EV ++LE +EE +L R +Y++ + S +S Sbjct: 443 -------LPFRADEEFGAMEVSDILE----YLQEEAVLH--RNGERYHWASESFPASNIS 489 Query: 464 YKVV-----------DIGSGKVIGRLDENFVMDLEEGMEFIMH-GRSWLVLEIDGENLII 511 + DI + ++IG +D M L +H G + V ++D ++ Sbjct: 490 LRSASQENVVIVDQSDIANVRIIGEMDRFSAMTLLHDEAIYLHEGVQYQVEKLDWDHKKA 549 Query: 512 KVRE 515 VR+ Sbjct: 550 YVRK 553 >pir||E64496 ATP-dependent RNA helicase homolog MJ1574 - Methanococcus jannaschii >gi|1592195|gb|AAB99590.1| (U67597) ATP-dependent RNA helicase, eIF-4A family, putative [Methanococcus jannaschii] Length = 684 Score = 113 bits (279), Expect = 1e-23 Identities = 131/505 (25%), Positives = 225/505 (43%), Gaps = 85/505 (16%) Query: 10 KEKFRELNRL-----------QIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKD 58 K K +E+N L Q++A K + K V++ T SGK+E L + ++ L + Sbjct: 29 KFKNKEINELIDALGFKLYLHQVKALKYLYNKKDVVVTTSTASGKSEIFRLAIFDNFLSN 88 Query: 59 GLPPISCLYIAPLKALNRDLLER------LKWWEAKTGIRIDVRHGDTTQYRRAKQVRNP 112 P L I P +AL + E+ L + ++ ++ GD +R + +++ Sbjct: 89 --PDDRYLLIYPTRALINNQYEKFSMENELFYKITNKRVKAEILTGDVGLEKRREILKDK 146 Query: 113 PHVLITTPETLPALLTVKSLRPYL---KNVRFVVVDEVTELIDNKRGAQLILNLKRLSLI 169 P+VL TTP+ L + +K+ YL KN++ +VVDE+ + G ++ KRL + Sbjct: 147 PNVLFTTPDMLHYQI-LKNHNNYLWLLKNLKLLVVDEL-HVYRGVFGTNMVYVFKRLLKL 204 Query: 170 ADFIR-----IGLSATVGNEEEV------KEWLGVDEIVKPPLKKRYKFKVLFPRPRPED 218 + + LSAT+ N +E +++ VD+ P +K P++ Sbjct: 205 LKRLNNNLQILCLSATLKNPKEFVKLLFNRDFEVVDKSYNPSSRKYLAIL------EPKN 258 Query: 219 KELAELLRVDVEVAARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRL---KTWGKPVEVH 275 + +LLR R + +V+ + + LVF +TR+ E L L K + K + + Sbjct: 259 LDNKQLLR---------RLIENLVDNNIKTLVFFDTRKETEKLMRFLLNSKVFYK-LSTY 308 Query: 276 HGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQY-MSPRQVNRLIQRAG 334 G+L K R E E K K G++ AL+ T+++ELGIDIG++DAVI Y + P + LIQR G Sbjct: 309 KGTLPKYVREEIEEKFKNGEILALLTTNALELGIDIGDLDAVINYGIPPDGIFSLIQRFG 368 Query: 335 RSKHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIKPYENALDVLAHFIVGLLIE 394 R+ R E ++ DY Y+ L+ L I +IE Sbjct: 369 RAGRRDKEALNIIVLRKDGLDYY-------------------YKEHLNELYERIRKGIIE 409 Query: 395 YQKLNVHEPYRMAKET-YPYRNLKWEHYLEVINVLEDAGIIRREEGILKLG--------- 444 Y +N+ + K Y LK + E+ + ++ EG +K+ Sbjct: 410 YMPVNIKNRFVTKKHLHYLISELKIVDFDELNDFEKEIVKELEREGKIKIYKNPITNKTE 469 Query: 445 -RRAFKYYFDNLSTIPDEVSYKVVD 468 R + + ++ T DE Y ++D Sbjct: 470 IRNVKQPIYSSIRTASDESYYLILD 494 >gi|11500032 SKI2-family helicase [Archaeoglobus fulgidus] Length = 691 Score = 109 bits (271), Expect = 1e-22 Identities = 127/496 (25%), Positives = 210/496 (41%), Gaps = 72/496 (14%) Query: 10 KEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIA 69 +E EL Q EA +++ GK++L+ PT +GKT A + ++ +K G LY+ Sbjct: 20 EEGIEELFPPQAEAVEKVFSGKNLLLAMPTAAGKTLLAEMAMVREAIKGG----KSLYVV 75 Query: 70 PLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTV 129 PL+AL + E K WE K G+RI + GD Y + +++TT E +L + Sbjct: 76 PLRALAGEKYESFKKWE-KIGLRIGISTGD---YESRDEHLGDCDIIVTTSEKADSL--I 129 Query: 130 KSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIR-IGLSATVGNEEEVK 188 ++ ++K V +VVDE+ L KRGA L + + ++ + +R IGLSAT N E+ Sbjct: 130 RNRASWIKAVSCLVVDEIHLLDSEKRGATLEILVTKMRRMNKALRVIGLSATAPNVTEIA 189 Query: 189 EWLGVDEIVKPPLKKRYKFKVLFPRPRPED---KELAELLRVDVEVAARLR---TLWEIV 242 EWL D Y P P E + EL + R++ + E V Sbjct: 190 EWLDAD----------YYVSDWRPVPLVEGVLCEGTLELFDGAFSTSRRVKFEELVEECV 239 Query: 243 EKHKRVLVFVNTRQFAEVLAHRLKT-WGKPVE---------------------------- 273 ++ VLVF +TR+ AE A +L K VE Sbjct: 240 AENGGVLVFESTRRGAEKTAVKLSAITAKYVENEGLEKAILEENEGEMSRKLAECVRKGA 299 Query: 274 -VHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQ-------YMSPRQ 325 HH L R E + G +K ++ T ++ G+++ +++ Y + Sbjct: 300 AFHHAGLLNGQRRVVEDAFRRGNIKVVVATPTLAAGVNLPARRVIVRSLYRFDGYSKRIK 359 Query: 326 VNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIKPYENALDVLA 385 V+ Q AGR+ ++ II G D I KR I G+ ERI L Sbjct: 360 VSEYKQMAGRAGRPGMDERGEAIIIVGKRD---REIAVKRYIFGEPERITSKLGVETHLR 416 Query: 386 HFIVGLLIEYQKLNVHEPYRMAKETYPYR--NLKWEHYLE-VINVLEDAGIIRREEGI-- 440 + ++ + + E +T+ ++ + + LE V+ LE+ G++ + + Sbjct: 417 FHSLSIICDGYAKTLEELEDFFADTFFFKQNEISLSYELERVVRQLENWGMVVEDHHLAP 476 Query: 441 LKLGRRAFKYYFDNLS 456 KLG + Y D L+ Sbjct: 477 TKLGSLVSRLYIDPLT 492 >pir||B75073 ATP-dependent RNA helicase homolog PAB1722 - Pyrococcus abyssi (strain Orsay) >gi|5458399|emb|CAB49887.1| (AJ248286) SIMILAR TO SEVERAL DNA HELICASES [Pyrococcus abyssi] Length = 872 Score = 109 bits (270), Expect = 1e-22 Identities = 104/358 (29%), Positives = 176/358 (49%), Gaps = 42/358 (11%) Query: 2 HILLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLP 61 H + K ++E +L Q+EA K + GK+V++ PT SGK+E L + + L+D Sbjct: 32 HEEVNKLVEELGFKLYSHQVEALKLLYSGKNVVVSTPTASGKSEIFRLFIFDEFLEDSSS 91 Query: 62 PISCLYIAPLKALNRDLLERLKW----WEAKTGIRI--DVRHGDTTQYRRAKQVRNPPHV 115 +Y P +AL + LE+ + + TG ++ + GD R + R P+V Sbjct: 92 TFLLIY--PTRALINNQLEKFERENEIFSKITGRKVGNSILTGDVELSERRRIRREKPNV 149 Query: 116 LITTPETL-----PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIA 170 + TTP+ L P L K L KN++ +VVDE+ + G+ + +RL L Sbjct: 150 IFTTPDMLHYNLLPRWLDYKWL---FKNLKLLVVDEL-HIYRGVFGSNVAYVFRRLFLRL 205 Query: 171 DFIRIG-----LSATVGNEEEVKE---WLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELA 222 +++ LSAT+ N ++ E +E+ + ++ ++F R ++L Sbjct: 206 RRLKVNPRILALSATLKNPKDFAEKFFGFEFEEVTEAGNPSPKRYIIMFEPTRFSGEQL- 264 Query: 223 ELLRVDVEVAARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKP---VEVHHGSL 279 +R VE +VE + LVF ++R+ E + R+ K + + G+L Sbjct: 265 --IRQIVE---------RLVENDVKTLVFFDSRKGTERIM-RMFLGSKVFNLITTYKGTL 312 Query: 280 SKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQ-VNRLIQRAGRS 336 +K R E +EGK+KAL+ T+++ELGID+G++DAVI Y P + LIQR GR+ Sbjct: 313 TKLERWRIESDFREGKLKALLTTNALELGIDVGDLDAVINYGIPSDGLFSLIQRFGRA 370 >gb|AAK42601.1| DNA helicase related protein [Sulfolobus solfataricus] Length = 715 Score = 105 bits (259), Expect = 3e-21 Identities = 120/507 (23%), Positives = 218/507 (42%), Gaps = 94/507 (18%) Query: 14 RELNRLQIEAFKR-ISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLK 72 ++LN Q EA K+ + +G +L+ +PTGSGKT A + +++ +LK+G +Y+ PL+ Sbjct: 29 KKLNPPQTEAVKKGLLDGNRLLLTSPTGSGKTLIAEMGIISFLLKNG---GKAIYVTPLR 85 Query: 73 ALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKSL 132 AL + K WE+ G ++ + GD Y ++ITT E L +L + Sbjct: 86 ALTNEKYLTFKDWES-IGFKVAMTSGD---YDTDDAWLKNYDIIITTYEKLDSLW--RHR 139 Query: 133 RPYLKNVRFVVVDEVTELIDNKRG---AQLILNLKRLSLIADFIRIGLSATVGNEEEVKE 189 +L + V+DE+ L D +RG + + KR +L+A LSAT+ N +++ + Sbjct: 140 PDWLNEANYFVLDELHYLNDPERGPVVESVTIRAKRRNLLA------LSATISNYKQIAK 193 Query: 190 WLGVDEI------------VKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRT 237 WLG + + V P +K+ ++ +LF D ++ D +A L + Sbjct: 194 WLGAEPVATNWRPVPLMEGVMYPERKKKEYTILF-----RDNTARKVHGDDAIIAYTLDS 248 Query: 238 LWEIVEKHKRVLVFVNTRQFAEVLAHRLKTW----------------------------- 268 L K+ +VLVF N+R+ AE A ++ + Sbjct: 249 L----SKNGQVLVFRNSRKMAESTALKIANYMNFVSLDEKAISEILKQLDDIEEGGSDEK 304 Query: 269 -------GKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGID-------IGEV 314 K V HH LSK R E ++ K+K ++ T ++ G++ IG++ Sbjct: 305 ELLKSLISKGVAYHHAGLSKALRDIIEESFRKRKIKVIVATPTLAAGVNLPARTVIIGDI 364 Query: 315 ----DAVIQYMSPRQVNRLIQRAGRS-KHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEG 369 ++ Y V Q +GR+ + ++ E+ I+ ED + + K+ I Sbjct: 365 YRFNRKIVGYYDEIPVMEYKQMSGRAGRPGFDQIGESIIVVRDKEDVDR---VFKKYILS 421 Query: 370 KLERIKPYENALDVLAHFIVGLLIEYQKLNVHEPYRMAKETYPYRNLKWEHYLEVINVLE 429 +E I+ + F++G+L L+ + A E+ +++ ++ I L Sbjct: 422 DVEPIESKLGSERAFYTFLLGILSAEGSLSEKQLEAFAYESLLAKSVVDVYFDRAIRWLS 481 Query: 430 DAGIIRREEGILKL---GRRAFKYYFD 453 + IR E L G+R Y + Sbjct: 482 EHSFIREENNTFTLTNFGKRVADLYIN 508 >pir||H82418 ATP-dependent RNA helicase, DEAD box family VCA0768 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9658191|gb|AAF96666.1| (AE004405) ATP-dependent RNA helicase, DEAD box family [Vibrio cholerae] Length = 422 Score = 101 bits (248), Expect = 5e-20 Identities = 89/326 (27%), Positives = 152/326 (46%), Gaps = 23/326 (7%) Query: 19 LQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKD------GLPPISCLYIAPLK 72 +Q +A + +GK VL A TG+GKT A LP++ ++ I L + P + Sbjct: 32 IQQQAIPHVLQGKDVLAGAQTGTGKTAAFGLPLIQRFIEQPWQREANSKEIRALVLVPTR 91 Query: 73 ALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKSL 132 L + +L+ L+ + T ++I +G T+ + +R +LI TP L VKSL Sbjct: 92 ELAQQVLDSLQAYAKGTELKIVAVYGGTSMKVQLNHLRGGVDILIATPGRLLDHAHVKSL 151 Query: 133 RPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGNEEEVKEWLG 192 +L V +V+DE ++D L L+RLS + + SAT ++ + + Sbjct: 152 --FLGKVEVLVLDEADRMLDMGFMPDLQRVLRRLSPLRQ--TLFFSATFDSKIKAVAY-- 205 Query: 193 VDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIV--EKHKRVLV 250 I++ P++ + P E + + V+ + L ++ + ++VLV Sbjct: 206 --RIMRDPIEVQVT-------PSNSTAETVQQMVYPVDKKRKRELLSYLIGSKNWQQVLV 256 Query: 251 FVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGID 310 F TRQ ++ LA LK G +G S+ AR +A K GKV+ALI T G+D Sbjct: 257 FTKTRQGSDALAEELKLDGIKAVSINGDKSQGARQKALDDFKAGKVRALIATDVAARGLD 316 Query: 311 IGEVDAVIQYMSPRQVNRLIQRAGRS 336 I +++ V+ Y P + + R GR+ Sbjct: 317 IAQLEQVVNYDMPFKAEDYVHRIGRT 342 >dbj|BAB05483.1| (AP001513) ATP-dependent RNA helicase [Bacillus halodurans] Length = 764 Score = 99.8 bits (245), Expect = 1e-19 Identities = 96/360 (26%), Positives = 169/360 (46%), Gaps = 31/360 (8%) Query: 1 MHILLKKAIKEK-FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDG 59 + I +++A++++ +L Q A++ +G+ V+ + PT SGKT LPV+ I +D Sbjct: 43 LDIRIREALEKRGIGQLYTHQNTAYECSEKGEHVVAVTPTASGKTLCYNLPVLQQIRRD- 101 Query: 60 LPPISCLYIAPLKALNRDLLERLKWWEAKTGIRID--VRHGDTTQYRRAKQVRNPPHVLI 117 LY+ P KAL +D L + GI + GDT R + VR HV+I Sbjct: 102 -ESSRALYLFPTKALAQDQKSELNEIIEEMGISVKCFTYDGDTAPNIR-QAVRKAGHVVI 159 Query: 118 TTPETLPALLTVKSLR--PYLKNVRFVVVDEVTEL--IDNKRGAQLILNLKRLSLI--AD 171 T P+ L + + + + +N+++VV+DE+ + A +I LKR++ ++ Sbjct: 160 TNPDMLHSAILPHHTKWVAFFENLKYVVIDELHTYRGVFGSHVANVIRRLKRIARYYGSE 219 Query: 172 FIRIGLSATVGNEEEVKEWLG------VDEIVKPPLKKRYKFKVLFPRPRPEDKELAELL 225 I SAT+ N +E+ L +D P KK + F P E + + Sbjct: 220 PTFICTSATIANPQELASQLTGHNVRLIDNNGAPSGKKHFVF--YNPPVVNEPLNIRKSA 277 Query: 226 RVDVEVAARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKP------VEVHHGSL 279 V+V A+ + +E + + +VF +R EV+ L+ K V + G Sbjct: 278 TVEVNRLAK-----KFLENNIQTIVFARSRVRVEVILSHLQELTKKKIGQQAVRGYRGGY 332 Query: 280 SKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHR 339 + R E ER L+ G + ++ T+++ELG+DIG++ I P + Q++GR+ R Sbjct: 333 LPKQRREIERGLRNGDIIGVVSTNALELGVDIGQLQVCIMTGYPGSIASAWQQSGRAGRR 392 >dbj|BAA34994.1| (AB017003) DjVLGB [Dugesia japonica] Length = 781 Score = 97.9 bits (240), Expect = 4e-19 Identities = 81/329 (24%), Positives = 149/329 (44%), Gaps = 22/329 (6%) Query: 19 LQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSIL----------KDGLPPISCLYI 68 +Q A I E + ++ A TGSGKT A ++P++N ++ K P CL + Sbjct: 210 IQKNAIPAILEHRDIMACAQTGSGKTAAFLIPIINHLVCQDLNQQRYSKTAYP--KCLIL 267 Query: 69 APLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLT 128 AP + L +L + + T +R V +G + + ++V+ H+L+ TP L + Sbjct: 268 APTRELAIQILSESQKFSLNTPLRSCVVYGGADTHSQIREVQMGCHLLVATPGRLVDFIE 327 Query: 129 VKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGNEEEVK 188 + L+ +++V+DE ++D Q+ ++ ++ + R L + +E++ Sbjct: 328 KNKIS--LEFCKYIVLDEADRMLDMGFEPQIRKIIEESNMPSGINRQTLMFSATFPKEIQ 385 Query: 189 EWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRV-DVEVAARLRTLWEIVEKHKR 247 + L D + Y F + D E++ + DVE L+ ++ + Sbjct: 386 K-LAADFLYN------YIFMTVGRVGSTSDSIKQEIIYMTDVEKLNYLKNIFNTTAPNTL 438 Query: 248 VLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMEL 307 +L+FV T++ A+ LA L + G PV HG S+ R A + G+ L+ T+ Sbjct: 439 ILIFVETKKGADSLARFLLSKGYPVSSIHGDRSQVEREAALSMFRNGQCPILVATAVAAR 498 Query: 308 GIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 G+DI V VI Y P + + R GR+ Sbjct: 499 GLDIPNVKHVINYDLPSDIEEYVHRIGRT 527 >sp|P34668|YO12_CAEEL PUTATIVE ATP-DEPENDENT RNA HELICASE ZK686.2 IN CHROMOSOME III >gi|630778|pir||S44912 hypothetical protein ZK686.2 - Caenorhabditis elegans >gi|304349|gb|AAA28223.1| (L17337) putative [Caenorhabditis elegans] Length = 696 Score = 97.5 bits (239), Expect = 6e-19 Identities = 94/354 (26%), Positives = 161/354 (44%), Gaps = 39/354 (11%) Query: 31 KSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLKALNRDLLERLKWWEAKTG 90 + V I APTGSGKT +LPV+ ++ + + + P++ L +++ K W ++G Sbjct: 260 RDVAIAAPTGSGKTICYVLPVLAAVGSKPSKILQAVILVPVQTLVAQIVDEFKRWNDESG 319 Query: 91 I-RIDVRHGDTTQYRRAKQV-RNPPHVLITTPETLPALLTVKSLRPY-LKNVRFVVVDEV 147 + ++ G + A+Q+ +PP+V++ TP L LT K P L +RF++VDE Sbjct: 320 VAKVVSLSGANDFEKEARQLASDPPNVIVATPARLVQHLTSKIPPPIDLSKLRFLIVDEA 379 Query: 148 TELIDNKRGAQLIL------NLKRLSLIADFIR-------IGLSATVGNE-EEVKEWLGV 193 + R L L ++R++ + D IR I LSAT+ + EE+ W Sbjct: 380 DRMGKLMREEWLDLVEFLCGGMERVACLKDIIRQRRAPQKIVLSATLSKDVEELHLW--- 436 Query: 194 DEIVKPPLKKRYKFKVL-FPRPRPEDKELAELLRVDVEVAARL---------RTLWEIVE 243 + KP L V P+ ++ L + ++ RL +++ + Sbjct: 437 -NLFKPRLFSATAVSVKDITSGIPQVDHVSGRLALPSSISHRLVVTDPKFHPLAVYQQIT 495 Query: 244 KHK--RVLVFVNTRQFAEVLAHRLKTWGK---PVEVHHGSLSKEARIEAERKLKEGKVKA 298 ++K R L+FVN + LAH LK K V+ L + R + K + + + Sbjct: 496 RNKFNRTLIFVNEVSSSNRLAHVLKELCKDQFEVDYFTAQLFGKRRYKMLEKFNKNENRV 555 Query: 299 LICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATG 352 LIC+ + G D+ +VD VI Y P + RAGR+ + Y+I+ G Sbjct: 556 LICSDVLARGTDLNKVDCVINYNLPADDKLFVHRAGRTGR---AGQDGYVISVG 606 >dbj|BAA91812.1| (AK001652) unnamed protein product [Homo sapiens] Length = 491 Score = 95.6 bits (234), Expect = 2e-18 Identities = 98/340 (28%), Positives = 155/340 (44%), Gaps = 19/340 (5%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ + F+ +Q++A + G+ +L APTGSGKT A +P++ + + Sbjct: 68 LLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGF 127 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRR-AKQVRNPPHVLITTPET 122 L I+P + L + L TG RI + H ++ + +L+TTP Sbjct: 128 RALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNR 187 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELI-DNKRGAQLILNLKRLSLIADFIRIGL-SAT 180 L LL L +V ++VVDE +L D K G + L L+ + +R + SAT Sbjct: 188 LIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSAT 247 Query: 181 VGNEEEVKEW--LGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTL 238 + V++W L +D ++ + R E E ELL V E +L + Sbjct: 248 FAYD--VEQWCKLNLDNVISVSIGAR--------NSAVETVE-QELLFVGSETG-KLLAV 295 Query: 239 WEIVEK--HKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKV 296 E+V+K + VLVFV + + A+ L H L G V+V H +++ R + GK+ Sbjct: 296 RELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKI 355 Query: 297 KALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 LICT+ + GID V+ VI Y P I R GR+ Sbjct: 356 WVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRT 395 >pir||S01676 ATP-dependent RNA helicase homolog - fruit fly (Drosophila melanogaster) Length = 660 Score = 94.4 bits (231), Expect = 5e-18 Identities = 85/340 (25%), Positives = 156/340 (45%), Gaps = 21/340 (6%) Query: 3 ILLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKD---- 58 I++ K F+ +Q + IS G+ ++ A TGSGKT A +LP+++ +L+D Sbjct: 255 IIIDNVNKSGFKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLEDPHEL 314 Query: 59 --GLPPISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVL 116 G P + + ++P + L + + + ++ ++I + +G T+ + + + HV+ Sbjct: 315 ELGRPQV--VIVSPTRELAIQIFNEARKFAFESYLKIGIVYGGTSFRHQNECITRGCHVV 372 Query: 117 ITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIG 176 I TP L L V ++ RFVV+DE ++D + + +++ + + Sbjct: 373 IATPGRL--LDFVDRTFITFEDTRFVVLDEADRMLDMGFSEDMRRIMTHVTMRPEHQTLM 430 Query: 177 LSATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLR 236 SAT EE++ G LK R+ V ++ + + + A R + Sbjct: 431 FSATF--PEEIQRMAGEF------LKLRF---VAIGIVGGRCSDVKQTIYEVNKYAKRSK 479 Query: 237 TLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKV 296 + + E+ +VFV T++ A+ LA L P HG + R +A R K G + Sbjct: 480 LIEILSEQADGTIVFVETKRGADFLASFLSEKEFPTTSIHGDRLQSQREQALRDFKNGSM 539 Query: 297 KALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 K LI TS G+DI + VI Y P +++ + R GR+ Sbjct: 540 KVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGRT 579 >pir||A31922 ATP-dependent RNA helicase homolog - fruit fly (Drosophila melanogaster) >gi|158796|gb|AAA29013.1| (M23560) Mab4611 antigen (vasa) [Drosophila melanogaster] Length = 648 Score = 94.4 bits (231), Expect = 5e-18 Identities = 85/340 (25%), Positives = 156/340 (45%), Gaps = 20/340 (5%) Query: 3 ILLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKD---- 58 I++ K ++ +Q + IS G+ ++ A TGSGKT A +LP+++ +L+D Sbjct: 242 IIIDNVNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLEDPHEL 301 Query: 59 --GLPPISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVL 116 G P + C+ ++P + L + + + ++ ++I + +G T+ + + + HV+ Sbjct: 302 ELGRPQV-CI-VSPTRELAIQIFNEARKFAFESYLKIGIVYGGTSFRHQNECITRGCHVV 359 Query: 117 ITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIG 176 I TP L L V ++ RFVV+DE ++D + + +++ + + Sbjct: 360 IATPGRL--LDFVDRTFITFEDTRFVVLDEADRMLDMGFSEDMRRIMTHVTMRPEHQTLM 417 Query: 177 LSATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLR 236 SAT EE++ G K Y F V ++ + + + A R + Sbjct: 418 FSATF--PEEIQRMAG-------EFLKNYVF-VAIGIVGGACSDVKQTIYEVNKYAKRSK 467 Query: 237 TLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKV 296 + + E+ +VFV T++ A+ LA L P HG + R +A R K G + Sbjct: 468 LIEILSEQADGTIVFVETKRGADFLASFLSEKEFPTTSIHGDRLQSQREQALRDFKNGSM 527 Query: 297 KALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 K LI TS G+DI + VI Y P +++ + R GR+ Sbjct: 528 KVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGRT 567 >gb|AAF44917.1|AE003406_122 (AE003416) symbol=vas; synonym=BG:DS00929.14; cDNA=method:''sim4'', score:''1000.0'', desc:''LD06084 LD Drosophila melanogaster embryo BlueScript Drosophila melanogaster cDNA clone LD06084 5prime, mRNA sequence:AA246989''; match=method:''sim4'', score:> >gi|7298204|gb|AAF53438.1| (AE003646) vas gene product [Drosophila melanogaster] Length = 661 Score = 94.4 bits (231), Expect = 5e-18 Identities = 84/340 (24%), Positives = 155/340 (44%), Gaps = 20/340 (5%) Query: 3 ILLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKD---- 58 I++ K ++ +Q + IS G+ ++ A TGSGKT A +LP+++ +L+D Sbjct: 255 IIIDNVNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLEDPHEL 314 Query: 59 --GLPPISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVL 116 G P + + ++P + L + + + ++ ++I + +G T+ + + + HV+ Sbjct: 315 ELGRPQV--VIVSPTRELAIQIFNEARKFAFESYLKIGIVYGGTSFRHQNECITRGCHVV 372 Query: 117 ITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIG 176 I TP L L V ++ RFVV+DE ++D + + +++ + + Sbjct: 373 IATPGRL--LDFVDRTFITFEDTRFVVLDEADRMLDMGFSEDMRRIMTHVTMRPEHQTLM 430 Query: 177 LSATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLR 236 SAT EE++ G K Y F V ++ + + + A R + Sbjct: 431 FSATF--PEEIQRMAG-------EFLKNYVF-VAIGIVGGACSDVKQTIYEVNKYAKRSK 480 Query: 237 TLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKV 296 + + E+ +VFV T++ A+ LA L P HG + R +A R K G + Sbjct: 481 LIEILSEQADGTIVFVETKRGADFLASFLSEKEFPTTSIHGDRLQSQREQALRDFKNGSM 540 Query: 297 KALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 K LI TS G+DI + VI Y P +++ + R GR+ Sbjct: 541 KVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGRT 580 >pir||E72775 probable helicase APE0191 - Aeropyrum pernix (strain K1) >gi|5103582|dbj|BAA79103.1| (AP000058) 702aa long hypothetical helicase [Aeropyrum pernix] Length = 702 Score = 94.4 bits (231), Expect = 5e-18 Identities = 112/420 (26%), Positives = 182/420 (42%), Gaps = 79/420 (18%) Query: 27 ISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLKALNRDLLERLKWWE 86 + +G+++++ APTGSGKT A++ ++NS+ + G Y+ PLK++ + Sbjct: 7 VEKGENLVVAAPTGSGKTFIALVAIVNSLARAG---GRAFYLVPLKSVAYEKYTSFSIL- 62 Query: 87 AKTGIRIDVRHGDTTQYRRAKQVRNPPH--VLITTPETLPALLTVKSLRPYLKNVRFVVV 144 ++ G+++ + GD + PP V+I T E +LL V +NV ++V Sbjct: 63 SRMGLKLKISVGDFRE--------GPPEAPVVIATYEKFDSLLRVSP--SLARNVSVLIV 112 Query: 145 DEVTELIDNKRGAQLILNLKR-LSLIADFIRIGLSATVGNEEEVKEWLG---VDEIVKPP 200 DE+ + D KRG L + R L+ + +GLSATV N E+ EW+G V+ +P Sbjct: 113 DEIHSVSDPKRGPILESIVSRMLASAGEAQLVGLSATVPNAGEIAEWIGGKIVESSWRPV 172 Query: 201 LKKRYKFKVLFPRPRPEDKELAELLRV----DVEVAARLRTLWEIVEKHKRVLVFVNTRQ 256 + Y FK + L E+ RV D+++AA E +E + LVF +R+ Sbjct: 173 PLREYVFKEY--KLYSPTGGLREVPRVYGLYDLDLAA------EAIEDGGQALVFTYSRR 224 Query: 257 FAEVLAHRL---------------------KTWGKP--------------VEVHHGSLSK 281 A LA R + G P + HH L Sbjct: 225 RAVTLAKRAAKRLGRRLSSREARVYSAEASRAEGAPRSVAEELASLIAAGIAYHHAGLPP 284 Query: 282 EARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQ--------YMSPRQVNRLIQRA 333 R E + G VK + T ++ G+++ VI + P +V Q A Sbjct: 285 SLRKTVEEAFRAGAVKVVYSTPTLAAGVNLPARRVVIDSYYRYEAGFREPIRVAEYKQMA 344 Query: 334 GRS-KHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIKPYENALDVLAHFIVGLL 392 GR+ + L E EA I+A + D + LI I ER++ L L HFI+G++ Sbjct: 345 GRAGRPGLDEFGEAIIVAERL-DRPEDLI--SGYIRAPPERVESRLAGLRGLRHFILGIV 401 >pir||T38420 probable dna helicases - fission yeast (Schizosaccharomyces pombe) (fragment) >gi|2656007|emb|CAB16187.1| (Z99126) DEAD/DEAH box helicase [Schizosaccharomyces pombe] Length = 643 Score = 93.6 bits (229), Expect = 9e-18 Identities = 86/327 (26%), Positives = 156/327 (47%), Gaps = 37/327 (11%) Query: 20 QIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLKALNRD-- 77 Q +A + G V++ T SGK+ +P++ S+L+D + ++ P K+L +D Sbjct: 316 QADAINHLWNGFHVIVSTSTSSGKSLIYQIPILQSLLEDNQS--TAFFVFPTKSLAQDQK 373 Query: 78 --LLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKSLRPY 135 L++ L + IR+D GDT R +R+ +++ T P+ L + + R Y Sbjct: 374 KSLIDILSYMPTLKNIRVDTFDGDTPLESRESIIRSA-NIIFTNPDMLHQTILPNANRWY 432 Query: 136 --LKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIR------IGLSATVGNE-EE 186 KN++ V+DE + + G + L+R+ IA++ + SAT+ + + Sbjct: 433 YFFKNLKLFVLDEA-HVYNGIFGVHVAFVLRRMRRIAEYFGNSQYRFVSCSATIEDPLQH 491 Query: 187 VKEWLGVDEIV------KPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWE 240 +K+ GVD I P K++ V++ P + K + + + A++L L + Sbjct: 492 MKKIFGVDNIKLINYTSSPSGSKKF---VMWNPPYVDPKHPDDGKKSAISEASKL--LIK 546 Query: 241 IVEKHKRVLVFVNTRQFAEVLAH----RLKTWGK-----PVEVHHGSLSKEARIEAERKL 291 EK R +VF R+ E L LKT K ++ + + + R + E ++ Sbjct: 547 FAEKRVRTIVFCRVRKTCESLMRLVRQELKTKQKGDLLSKIQSYRAGYTVQERRKIESEM 606 Query: 292 KEGKVKALICTSSMELGIDIGEVDAVI 318 GK+ +I T+++ELGIDIG +DAVI Sbjct: 607 FNGKLYGIIATNALELGIDIGSLDAVI 633 >pir||F70354 ATP-dependent RNA helicase DeaD - Aquifex aeolicus >gi|2983229|gb|AAC06826.1| (AE000698) ATP-dependent RNA helicase DeaD [Aquifex aeolicus] Length = 293 Score = 92.4 bits (226), Expect = 2e-17 Identities = 85/296 (28%), Positives = 138/296 (45%), Gaps = 20/296 (6%) Query: 29 EGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLKALNRDLLERLKWWEAK 88 +G+ LI A TG+GKT A LP++NS LK+G L +AP + L + + + + Sbjct: 8 QGRDCLIQAKTGTGKTAAFGLPILNS-LKEGE---KALILAPTRELALQIRDNFRDFARY 63 Query: 89 TGIRIDVRHGDTTQYRRAKQVRNPP-HVLITTPETLPALLTVKSLRPYLKNVRFVVVDEV 147 +R +G T + K +R V+I TP + L+ +L+ +VR+ V+DEV Sbjct: 64 LNVRTFAFYGGTKVFGDLKVLRGGKVDVVIGTPGRIKDLIERGALKT--DDVRYFVLDEV 121 Query: 148 TELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGNEEEVKEWLGVDEIVKPPLKKRYKF 207 ++D + +L + SAT E V E+ KK Sbjct: 122 DVMLDMNFKEDIDFIYSQLPEEKQVFFV--SATFPKE--------VRELSHRYTKKPEFI 171 Query: 208 KVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRLKT 267 KV P+ +E LLRV + ++ L +++ +V+VFVN ++ A+ L +L T Sbjct: 172 KVESRELEPQIEE--RLLRV-YSIREKIELLEDVLRDFNKVIVFVNRKRDAKFLGEKLST 228 Query: 268 WGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSP 323 G V HG L + R E +K + G + L+ T G+DI EV+AV+ + P Sbjct: 229 KGFRVGALHGDLPQRRREEILKKFRRGFINVLVATDVASRGLDISEVEAVVNFHLP 284 >prf||1413329A gene vasa [Drosophila melanogaster] Length = 660 Score = 91.3 bits (223), Expect = 4e-17 Identities = 84/340 (24%), Positives = 155/340 (44%), Gaps = 21/340 (6%) Query: 3 ILLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKD---- 58 I++ K F+ +Q + IS G+ ++ A TGSGKT A +LP+++ +L+D Sbjct: 255 IIIDNVNKSGFKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLEDPHEL 314 Query: 59 --GLPPISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVL 116 G P + + ++P + L + + + ++ ++I + +G T+ + + + HV+ Sbjct: 315 ELGRPQV--VIVSPTRELAIQIFNEARKFAFESYLKIGIVYGGTSFRHQNECITRGCHVV 372 Query: 117 ITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIG 176 I TP L L V ++ RFVV+DE ++D + + +++ + + Sbjct: 373 IATPGRL--LDFVDRTFITFEDTRFVVLDEADRMLDMGFSEDMRRIMTHVTMRPEHQTLM 430 Query: 177 LSATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLR 236 SAT EE++ G LK R+ V ++ + + + A R + Sbjct: 431 FSATF--PEEIQRMAGEF------LKLRF---VAIGIVGGRCSDVKQTIYEVNKYAKRSK 479 Query: 237 TLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKV 296 + + E+ +VFV T++ A+ LA L P G + R +A R K G + Sbjct: 480 LIEILSEQADGTIVFVETKRGADFLASFLSEKEFPTTSIRGDRLQSQREQALRDFKNGSM 539 Query: 297 KALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 K LI TS G+DI + VI Y P +++ + R GR+ Sbjct: 540 KVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGRT 579 >pir||T39188 probable U5 snRNP-specific 200kd protein - fission yeast (Schizosaccharomyces pombe) >gi|6014422|emb|CAB57421.1| (AL121764) putative U5 snRNP-specific 200kd protein [Schizosaccharomyces pombe] Length = 2176 Score = 91.3 bits (223), Expect = 4e-17 Identities = 105/431 (24%), Positives = 186/431 (42%), Gaps = 85/431 (19%) Query: 14 RELNRLQIEAFK-RISEGKSVLIIAPTGSGKTEAAILPVMNSILKD-------GLPPISC 65 + LNR+Q + +++L+ APTG+GKT A+L ++N + K L Sbjct: 518 QSLNRIQSHLYPIAFGTDENILLCAPTGAGKTNVAMLCILNELQKHLREDLSFNLQNFKI 577 Query: 66 LYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPA 125 +YIAPLKAL ++++ IR+ GD+ + KQ + +++TTPE Sbjct: 578 VYIAPLKALVQEMVNNFSKRLTPYNIRVAELTGDS---QLTKQQISETQIIVTTPEKWDI 634 Query: 126 LLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRL-----SLIADFIRIGLSAT 180 + + Y+ VR V++DEV L+ ++RG L + R+ + +GLSAT Sbjct: 635 ITRKANDLSYVNLVRLVIIDEV-HLLHDERGPVLESIVARIFRHQEETLEQVRLVGLSAT 693 Query: 181 VGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRT--- 237 + N +V +L VD P K + F + RP P +E + + R++T Sbjct: 694 LPNYTDVASFLHVD-----PKKGLFYFDSTY-RPCPLKQEFIGI--TEKTPFKRMQTTNE 745 Query: 238 -LWEIVEKH---KRVLVFVNTRQFA--------------EVLAHRLKTWGKPVE------ 273 +E V +H +VL+FV++R+ E + H L++ E Sbjct: 746 ACYEKVMQHAGKNQVLIFVHSRKETAKTARFIRDKALEEETIGHLLRSDAASREILRAEA 805 Query: 274 -----------------VHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDA 316 +HH + +E R +E +G ++ L+ T+++ G+++ Sbjct: 806 DSTSDENLKDLLPYGFAIHHAGMRREDRQTSEDLFADGTIQVLVSTATLAWGVNLPAHTV 865 Query: 317 VIQ-------------YMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVE-DYLQSLII 362 +I+ +SP+ V +++ RAGR + E II E Y SL+ Sbjct: 866 IIKGTQVYSPEKGIWTELSPQDVLQMLGRAGRPQFD--TYGEGIIITAHSELQYYLSLMN 923 Query: 363 AKRAIEGKLER 373 + IE + R Sbjct: 924 QQLPIESQFMR 934 >gb|AAF58994.1| (AE003834) Dbp45A gene product [Drosophila melanogaster] Length = 521 Score = 90.9 bits (222), Expect = 6e-17 Identities = 84/346 (24%), Positives = 151/346 (43%), Gaps = 34/346 (9%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 L+K+ K + +Q + I G+ + A TGSGKT A LP++ + ++ P+ Sbjct: 18 LVKQLTKLGLKGATPIQQKCIPAILAGQDCIGAAKTGSGKTFAFALPILERLSEE---PV 74 Query: 64 S--CLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPE 121 S L + P L + E+ G+R+ V G T Q ++++ PH+++ P Sbjct: 75 SHFALVLTPTHELAYQISEQFLVAGQAMGVRVCVVSGGTDQMVESQKLMQRPHIVVAMPG 134 Query: 122 TLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLIL----------NLKRLSLIAD 171 L LT + N++++VVDE +++ L + NL + + D Sbjct: 135 RLADHLTGCDTFSF-DNLKYLVVDEADRMLNGDFDESLSIIERCLPKTRQNLFFSATMKD 193 Query: 172 FIRIGLSATVGNEEEVKEWLGVDEIVK-PPLKKRYKFKVLFPRPRPEDKELAELLRVDVE 230 FI+ + ++ EW ++ L +RY + R D L E LR E Sbjct: 194 FIKESSIFPIASD--CFEWSQDSDVATVETLDQRYLLCADYDR----DMVLIEALRKYRE 247 Query: 231 VAARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERK 290 ++ V++F NT+++ ++L+ LK HG + ++ R+ A + Sbjct: 248 E-----------NENANVMIFTNTKKYCQLLSMTLKNMEIDNVCLHGFMRQKERVAALSR 296 Query: 291 LKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 K +++ LI T G+DI V+ V+ +M PR I R GR+ Sbjct: 297 FKSNQIRTLIATDVAARGLDIPSVELVMNHMLPRTPKEYIHRVGRT 342 >emb|CAB90153.1| (AL355013) putative atp-dependent RNA helicase [Schizosaccharomyces pombe] Length = 465 Score = 90.1 bits (220), Expect = 1e-16 Identities = 91/332 (27%), Positives = 144/332 (42%), Gaps = 29/332 (8%) Query: 13 FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLK 72 F+ +Q EA + + V+ +A TGSGKT A LPV+ L + P + +AP + Sbjct: 66 FKTPTPIQQEAIPVVLNKRDVIGLAQTGSGKTAAFALPVIQE-LWNNPSPFFAVVLAPTR 124 Query: 73 ALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTP-ETLPALLTVKS 131 L + E+ + G+R V G +A + PHVL+ TP + L K Sbjct: 125 ELAYQISEQFEAIGGSIGVRSVVIVGGMDMVTQAVALSKKPHVLVCTPGRLMDHLENTKG 184 Query: 132 LRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGL-SATVGNEEEVKEW 190 LKN++++++DE L+D G + K L +I R L SAT+ ++ E + Sbjct: 185 FS--LKNLKYLIMDEADRLLDMDFGPIID---KILKIIPHERRTLLFSATMTSKVEKLQR 239 Query: 191 LGVDEIVKPPLKKRYKF------KVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEK 244 + + V+ + ++ + LF + +D L L+ E+A Sbjct: 240 ASLHQPVRVAVSSKFSTVDTLIQRYLFFPFKHKDTYLVYLVN---ELAG----------- 285 Query: 245 HKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSS 304 +++F T + LA L+T G HG LS+ R+ A K K G L+ T Sbjct: 286 -NSIIIFARTVNDTQRLAILLRTLGFSAIPLHGQLSQSNRLGALNKFKSGARSTLVATDV 344 Query: 305 MELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 G+DI VD VI Y P I R GR+ Sbjct: 345 AARGLDIPLVDVVINYDIPTDSKAYIHRVGRT 376 >gi|6321020 putative ATP-dependent RNA helicase; Brr2p [Saccharomyces cerevisiae] >gi|731380|sp|P32639|BRR2_YEAST PRE-MRNA SPLICING HELICASE BRR2 >gi|1077724|pir||S50675 pre-mRNA splicing helicase BRR2 - yeast (Saccharomyces cerevisiae) >gi|603413|gb|AAB64699.1| (U18922) Brr2p: Putative ATP-dependent RNA helicase [Saccharomyces cerevisiae] >gi|1699380|gb|AAB37500.1| Rss1p=ATP-dependent RNA helicase homolog [Saccharomyces cerevisiae, Peptide Mutant, 2163 aa] Length = 2163 Score = 90.1 bits (220), Expect = 1e-16 Identities = 100/393 (25%), Positives = 175/393 (44%), Gaps = 81/393 (20%) Query: 16 LNRLQIEAFKRISEGKS-VLIIAPTGSGKTEAAILPVMNSI--------LKDGLPPISCL 66 LN +Q + F EG S +LI APTGSGKT A+L V+ ++ K L + Sbjct: 499 LNPIQSKVFHAAFEGDSNMLICAPTGSGKTNIALLTVLKALSHHYNPKTKKLNLSAFKIV 558 Query: 67 YIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPAL 126 YIAPLKAL ++ + + A GI++ GD+ R +++ + VL++TPE Sbjct: 559 YIAPLKALVQEQVREFQRRLAFLGIKVAELTGDS---RLSRKQIDETQVLVSTPEKWDIT 615 Query: 127 LTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIR-----IGLSATV 181 + ++ VR +++DE+ L+ + RG L + R + + + IGLSAT+ Sbjct: 616 TRNSNNLAIVELVRLLIIDEI-HLLHDDRGPVLESIVARTFWASKYGQEYPRIIGLSATL 674 Query: 182 GNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPED------KELAELLRVDVEVAARL 235 N E+V +L V P + + F F RP P KE L ++ A Sbjct: 675 PNYEDVGRFLRV------PKEGLFYFDSSF-RPCPLSQQFCGIKERNSLKKLKAMNDACY 727 Query: 236 RTLWEIVEKHKRVLVFVNTR------------QFAEV-LAHRL----------------- 265 + E + + +++VFV++R +FAE + H+L Sbjct: 728 EKVLESINEGNQIIVFVHSRKETSRTATWLKNKFAEENITHKLTKNDAGSKQILKTEAAN 787 Query: 266 -------KTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVI 318 K + HH L++ R +E +G ++ L+CT+++ G+++ +I Sbjct: 788 VLDPSLRKLIESGIGTHHAGLTRSDRSLSEDLFADGLLQVLVCTATLAWGVNLPAHTVII 847 Query: 319 -------------QYMSPRQVNRLIQRAGRSKH 338 + +SP+ V +++ RAGR ++ Sbjct: 848 KGTDVYSPEKGSWEQLSPQDVLQMLGRAGRPRY 880 >pir||H64474 hypothetical protein MJ1401 - Methanococcus jannaschii >gi|1592049|gb|AAB99409.1| (U67580) putative ATP dependent RNA helicase [Methanococcus jannaschii] Length = 808 Score = 89.7 bits (219), Expect = 1e-16 Identities = 92/364 (25%), Positives = 176/364 (48%), Gaps = 42/364 (11%) Query: 5 LKKAIKEK-FRELNRLQIEAFKR-ISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP 62 LK+ IK + EL +Q + K + G +LII+ T SGKT L + +++K G Sbjct: 200 LKEIIKSRGIEELLPVQTLSVKAGLLNGDDLLIISATSSGKTLIGELAGIKNLIKTGK-- 257 Query: 63 ISCLYIAPLKAL-NRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAK-QVRNPPHVLITTP 120 L++ PL AL N+ LE + +E K G ++ +R G ++ + +++ T Sbjct: 258 -KFLFLVPLVALANQKYLEFKERYE-KLGFKVSLRVGLGRIGKKVDVETSLDADIIVGTY 315 Query: 121 ETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLS-LIADFIRIGLSA 179 E + L+ K L K++ VV+DE+ L +RGA+L + RL L + +I LSA Sbjct: 316 EGIDYLIRTKRL----KDIGTVVIDEIHSLNLEERGARLDGLIGRLRFLFKEAQKIYLSA 371 Query: 180 TVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELA----ELLRVDVEVAARL 235 T+GN +E+ + L K + RP P ++ + + ++++ + + Sbjct: 372 TIGNPKELAKQLNA------------KLVLYNGRPVPLERHIIFCKNDFAKLNI-IKEIV 418 Query: 236 RTLWEIVEK---HKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLK 292 + W+ + K + L+F +R+ AE LA LK+ G E +HG + R + E Sbjct: 419 KREWQNISKFGYRGQCLIFTYSRKRAEYLAKALKSKGIKAEFYHGGMEYIKRRKVEDDFA 478 Query: 293 EGKVKALICTSSMELGIDIGEVDAVIQ-------YMSPRQVNRLIQRAGRSKHRLLEVSE 345 K++ ++ T+++ G+D +++ +++P + ++ RAGR + E+ + Sbjct: 479 NQKIQCVVTTAALSAGVDFPASTVILESLAMGADWLNPAEFQQMCGRAGRK--GMHEIGK 536 Query: 346 AYII 349 Y++ Sbjct: 537 VYLL 540 >pir||D82203 ATP-dependent RNA helicase RhlE VC1407 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9655903|gb|AAF94564.1| (AE004219) ATP-dependent RNA helicase RhlE [Vibrio cholerae] Length = 397 Score = 89.3 bits (218), Expect = 2e-16 Identities = 85/380 (22%), Positives = 172/380 (44%), Gaps = 30/380 (7%) Query: 3 ILLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP 62 +L++ + +++ +Q +A I +G+ ++ A TG+GKT + +LP++ L+ G Sbjct: 11 VLVQTVAQLGYQKPTHIQTQAIPVILQGRDLIAAAQTGTGKTASFVLPILEK-LRQGQTQ 69 Query: 63 ----ISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLIT 118 + L + P + L + E+++ + TG++ G + + +++ + VL+ Sbjct: 70 RKKRVRALILVPTRELAMQVAEKVEQYGKDTGLKSLAVFGGVDEQAQKQRLIDGVDVLVA 129 Query: 119 TPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLS 178 TP L L +++ Y + + VV+DE ++D G +N L ++ + S Sbjct: 130 TPGRLMDLYGQRAV--YFEEIEMVVLDEADRMLD--MGFIESINKIIDCLPSEVQFLLFS 185 Query: 179 ATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTL 238 AT+ + V E+ K ++ ++ + + + L+ VD + + L + Sbjct: 186 ATLSRK--------VRELAKTAVRDPHEISIAANQASKSNIS-QWLITVDKDTKSALLSH 236 Query: 239 WEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKA 298 ++ + L+F+ T+ A L +L+ G E H S+ R + K GK+K Sbjct: 237 LINEQQWDQALIFIETKHGAAKLVSQLEKRGIHAEAFHSGRSQAIRAQLLEDFKSGKIKY 296 Query: 299 LICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQ 358 L+ T GIDI ++ V+ Y P + + R GR+ R V EA I+ +D + Sbjct: 297 LVATGVAARGIDIDQLSRVVNYDLPFPADEYVHRIGRT-GRAEAVGEA--ISFVSKDNFK 353 Query: 359 SL---------IIAKRAIEG 369 +L +I +R +EG Sbjct: 354 NLCMIESRLGHLIERRVVEG 373 >gi|9755332 C4 zinc finger DNA-binding protein of low sequence specificity in vitro; Probable 119 kD DNA/RNA helicase family member; Hfm1p [Saccharomyces cerevisiae] Length = 1187 Score = 88.5 bits (216), Expect = 3e-16 Identities = 118/442 (26%), Positives = 186/442 (41%), Gaps = 88/442 (19%) Query: 12 KFRELNRLQIEAFKRISEG-KSVLIIAPTGSGKT---EAAILPVMNSILKDGLPPISCLY 67 KF E N++Q EAF I E ++ +I +PTGSGKT E AIL ++ D +Y Sbjct: 135 KFTEFNKMQSEAFPSIYESNENCIISSPTGSGKTVLFELAILRLIKETNSD-TNNTKIIY 193 Query: 68 IAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTT--QYRRAKQVRNPPHVLITTPETLPA 125 IAP K+L ++ + W+ + + + + DT+ + +AK+ +++ITTPE Sbjct: 194 IAPTKSLCYEMYKN--WFPSFVNLSVGMLTSDTSFLETEKAKKC----NIIITTPEKWDL 247 Query: 126 LLTVKSLRPYL-KNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIR-IGLSATVGN 183 L S L + V+ V+VDE+ I KRGA L + L R++ + IR + LSATV N Sbjct: 248 LTRRWSDYSRLFELVKLVLVDEI-HTIKEKRGASLEVILTRMNTMCQNIRFVALSATVPN 306 Query: 184 EEEVKEW-----------LGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVA 232 E++ W L DE + ++ + F K+ A Sbjct: 307 IEDLALWLKTNNELPANILSFDESYRQVQLTKFVYGYSFNCKNDFQKD-----------A 355 Query: 233 ARLRTLWEIVEKH---KRVLVFVNTRQFAEVLAHRL-----------------------K 266 L EI+EKH + VL+F TR A L + Sbjct: 356 IYNSKLIEIIEKHADNRPVLIFCPTRASTISTAKFLLNNHIFSKSKKRCNHNPSDKILNE 415 Query: 267 TWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEV-----------D 315 + + HH +S E R E++ G + L TS++ +G+++ Sbjct: 416 CMQQGIAFHHAGISLEDRTAVEKEFLAGSINILCSTSTLAVGVNLPAYLVIIKGTKSWNS 475 Query: 316 AVIQYMSPRQVNRLIQRAGR------------SKHRLLEVSEAYIIATGV-EDYLQSLII 362 + IQ S V ++I RAGR + ++ + E I T V E L +I Sbjct: 476 SEIQEYSDLDVLQMIGRAGRPQFETHGCAVIMTDSKMKQTYENLIHGTDVLESSLHLNLI 535 Query: 363 AKRAIEGKLERIKPYENALDVL 384 A E LE + E A++ L Sbjct: 536 EHLAAETSLETVYSIETAVNWL 557 >gi|6320497 Ydr291wp [Saccharomyces cerevisiae] >gi|2131417|pir||S70120 ATP-dependent RNA helicase homolog YDR291w - yeast (Saccharomyces cerevisiae) >gi|1230655|gb|AAB64466.1| (U51031) Ydr291wp [Saccharomyces cerevisiae] Length = 1077 Score = 88.5 bits (216), Expect = 3e-16 Identities = 96/361 (26%), Positives = 164/361 (44%), Gaps = 64/361 (17%) Query: 20 QIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLKALNRDLL 79 Q +A + +G++V+I T SGK+ L ++ +LKD P + +YI P KAL +D Sbjct: 295 QADAINSLHQGENVIITTSTSSGKSLIYQLAAIDLLLKD--PESTFMYIFPTKALAQDQK 352 Query: 80 ERLKWW-----EAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVK--SL 132 K E K + +D GDT RA +R V+ T P+ + + + Sbjct: 353 RAFKVILSKIPELKNAV-VDTYDGDTEPEERA-YIRKNARVIFTNPDMIHTSILPNHANW 410 Query: 133 RPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIR-------IGLSATVGNE- 184 R +L +++ VVVDE+ + G+ + L ++RL + I SAT+ + Sbjct: 411 RHFLYHLKLVVVDEL-HIYKGLFGSHVALVMRRLLRLCHCFYENSGLQFISCSATLKSPV 469 Query: 185 EEVKEWLGVDEIV-----------------KPPL-----KKRYKFKVLFPRPRPEDKELA 222 + +K+ G++E+ PP+ +KR F R K L Sbjct: 470 QHMKDMFGINEVTLIHEDGSPTGAKHLVVWNPPILPQHERKRENFI------RESAKILV 523 Query: 223 ELLRVDVEVAA--RLRTLWEIVEKHKRVLVFVNTRQ--FAEVLAHRLKTWGKPVEVHHGS 278 +L+ +V A +R + E++ K R + R+ EV+++R G Sbjct: 524 QLILNNVRTIAFCYVRRVCELLMKEVRNIFIETGREDLVTEVMSYR------------GG 571 Query: 279 LSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKH 338 S R + ER++ G +KA+I T+++ELGIDIG +DAV+ P + Q++GR+ Sbjct: 572 YSASDRRKIEREMFHGNLKAVISTNALELGIDIGGLDAVLMCGFPLSMANFHQQSGRAGR 631 Query: 339 R 339 R Sbjct: 632 R 632 >pir||A82872 ATP-dependent RNA helicase UU582 [imported] - Ureaplasma urealyticum >gi|6899592|gb|AAF30996.1|AE002157_1 (AE002157) ATP-dependent RNA helicase [Ureaplasma urealyticum] Length = 443 Score = 87.8 bits (214), Expect = 5e-16 Identities = 79/336 (23%), Positives = 155/336 (45%), Gaps = 21/336 (6%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 +L I +K E +Q++ I++ ++++ +APTG+GKT A +LP++N++ D + Sbjct: 11 ILDSLINQKIFEPTPIQLKTMPLIAKRENIIGVAPTGTGKTLAFVLPILNNL--DLSQKL 68 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGI-RIDVRHGDTTQYRRAKQVRNPPHVLITTPET 122 + I P + L R + ++ ++ + ++ + G + ++ N +LI TP Sbjct: 69 QVIIITPTRELARQIFSKIIVFKKHQPLLQVKMLIGGESIDQQINSQLNKSQLLIATPTR 128 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVG 182 L +LT + L L +V +V DE L+D L I+D I T Sbjct: 129 LKQILTRQILD--LHHVNALVFDEADMLMD-------------LGFISDLEFINSQFTNK 173 Query: 183 NEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRP--EDKELAELLRVDVEVAARLRTLWE 240 + +++ + E++ LKK +K + E+K++ + + + L + + Sbjct: 174 DVQKISFSATLHEMLSIQLKKYFKNTKIINISNSIYENKKITHYVIHNHDKWHSLSIIMK 233 Query: 241 IVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALI 300 ++ + ++F NT++ E + L K V + HGSL + R R +K K + ++ Sbjct: 234 TIKPYL-CIIFANTKKEVEAIYQYLIQQNKNVCILHGSLLQRERKNNYRDIKNNKFQYVV 292 Query: 301 CTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 + G+DI V +I + P + I RAGRS Sbjct: 293 ASDIASRGLDIDGVSHIINWNLPTENEWYIHRAGRS 328 >gi|6321360 ATP-dependent RNA helicase CA3 of the DEAD/DEAH box family; Dbp3p [Saccharomyces cerevisiae] >gi|1708151|sp|P20447|DBP3_YEAST PROBABLE ATP-DEPENDENT RNA HELICASE DBP3 (HELICASE CA3) >gi|320699|pir||S30805 probable RNA helicase CA3 - yeast (Saccharomyces cerevisiae) >gi|172582|gb|AAA73137.1| (M80437) [Saccharomyces cerevisiae gene, complete cds.], gene product >gi|1322595|emb|CAA96783.1| (Z72600) ORF YGL078c [Saccharomyces cerevisiae] Length = 523 Score = 87.0 bits (212), Expect = 8e-16 Identities = 91/354 (25%), Positives = 160/354 (44%), Gaps = 22/354 (6%) Query: 12 KFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP-ISCLYIAP 70 KF + +Q A+ + GK V+ +A TGSGKT A +P ++ ++ D I L I+P Sbjct: 131 KFPKPTPIQAVAWPYLLSGKDVVGVAETGSGKTFAFGVPAISHLMNDQKKRGIQVLVISP 190 Query: 71 LKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVK 130 + L + + L K G++ +G + + Q++ V++ TP L LL Sbjct: 191 TRELASQIYDNLIVLTDKVGMQCCCVYGGVPKDEQRIQLKKS-QVVVATPGRLLDLLQEG 249 Query: 131 SLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGNEEEVKEW 190 S+ L V ++V+DE +++ K + I N+ R + + + +AT E Sbjct: 250 SVD--LSQVNYLVLDEADRMLE-KGFEEDIKNIIRETDASKRQTLMFTATWPKE------ 300 Query: 191 LGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEKH----- 245 V E+ + K + +K + +++ V V+ + R L E+++K+ Sbjct: 301 --VRELASTFMNNPIKVSIGNTDQLTANKRITQIVEV-VDPRGKERKLLELLKKYHSGPK 357 Query: 246 --KRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTS 303 ++VL+F ++ A + LK G V HG LS++ R +A + K GK L+ T Sbjct: 358 KNEKVLIFALYKKEAARVERNLKYNGYNVAAIHGDLSQQQRTQALNEFKSGKSNLLLATD 417 Query: 304 SMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYL 357 G+DI V VI P V + R GR+ R + A+ + T E +L Sbjct: 418 VAARGLDIPNVKTVINLTFPLTVEDYVHRIGRT-GRAGQTGTAHTLFTEQEKHL 470 >gb|AAF48446.1| (AE003498) CG6227 gene product [Drosophila melanogaster] Length = 1224 Score = 86.6 bits (211), Expect = 1e-15 Identities = 90/365 (24%), Positives = 161/365 (43%), Gaps = 18/365 (4%) Query: 13 FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSIL-----KDGLPPISCLY 67 F + +Q +A I G+ ++ IA TGSGKT A ILP+ IL +DG I+ + Sbjct: 530 FEKPTPIQCQAIPAIMSGRDLIGIAKTGSGKTLAFILPMFRHILDQPSMEDGDGAIAII- 588 Query: 68 IAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALL 127 +AP + L + + ++ + G+R +G T + +++ +++ TP + +L Sbjct: 589 MAPTRELCMQIGKDIRKFSKSLGLRPVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDML 648 Query: 128 TVKSLR-PYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGNEEE 186 S R L+ V +VV+DE + D Q++ + + D + SAT + E Sbjct: 649 AANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIIDNVR--PDRQTVMFSATFPRQME 706 Query: 187 VKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEKHK 246 I+K P++ + + + E ++ +L D + +L L I ++ Sbjct: 707 AL----ARRILKKPIEVIVGGRSVVCK---EVEQHVVILNDDAKFF-KLLELLGIYQEAG 758 Query: 247 RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSME 306 ++VFV+ ++ A++L L P HG + + R K GKV+ LI TS Sbjct: 759 SIIVFVDKQENADILLRDLMKASYPCMSLHGGIDQFDRDSTIIDFKSGKVRLLIATSVAA 818 Query: 307 LGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKRA 366 G+D+ ++ V+ Y P + R GR+ R + AY T + II Sbjct: 819 RGLDVKDLILVVNYDVPNHYEDYVHRCGRT-GRAGKKGSAYTFITPEQSRYAGDIIRAMD 877 Query: 367 IEGKL 371 + G L Sbjct: 878 LSGTL 882 >pir||T36671 probable helicase - Streptomyces coelicolor >gi|4539568|emb|CAB38487.1| (AL035636) putative helicase [Streptomyces coelicolor A3(2)] Length = 815 Score = 86.2 bits (210), Expect = 1e-15 Identities = 132/530 (24%), Positives = 222/530 (40%), Gaps = 75/530 (14%) Query: 29 EGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP----ISCLYIAPLKALNRDLLERLKW 84 +G SV++ T SGK+ A ++PV+++++ P + LY+AP KAL D +K Sbjct: 104 DGDSVVVATGTASGKSLAYLVPVLSALVDGSEAPNGRGATTLYLAPTKALAADQCRSVKE 163 Query: 85 WEAKTG--IRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKSLR--PYLKNVR 140 G +R V GDT + + +R ++T P+ L + R +LK ++ Sbjct: 164 LSQPLGTSVRAAVYDGDTP-FEEREWIRQYGTYVLTNPDMLHRGILPSHPRWSSFLKALK 222 Query: 141 FVVVDEVTEL--IDNKRGAQLILNLKRLSLI--ADFIRIGLSATVGNEEEVKEWLGVDEI 196 +VV+DE + AQ++ L+RL A + + SAT L + Sbjct: 223 YVVIDECHTYRGVFGSHVAQVLRRLRRLCARYGASPVFLLASATAAEPSVAARRLTGLPV 282 Query: 197 VKPPLKKRYKFKVLFPRPRPEDKEL-----AELLRVDVEVAARLRTLWEIVEKHKRVLVF 251 ++ + +++F P EL A + R AA L T ++ + R + F Sbjct: 283 IEVADDASPRGELVFALWEPPLTELEGEKGAPVRRTATAEAADLLT--DLTVQGMRSITF 340 Query: 252 VNTRQFAEVLA----HRL----KTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTS 303 V +R+ AE+++ RL ++ V + G E R ER L G + L T+ Sbjct: 341 VRSRRGAELISVIAQERLAEVDRSLAGRVAAYRGGYLPEERRALERALHSGDLLGLAATN 400 Query: 304 SMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIA 363 ++ELG+DI +DAV+ P L Q+AGR A Sbjct: 401 ALELGLDISGLDAVVIAGYPGTRASLWQQAGR---------------------------A 433 Query: 364 KRAIEGKLERIKPYENALDV-LAHFIVGLL---IEYQKLNVHEPYRMAKE---------- 409 RA +G L + ++ LD L H L +E L+ PY +A Sbjct: 434 GRAGQGALAVLVARDDPLDTFLVHHPEALFDQPVESTVLDPDNPYVLAPHLCAAAAELPL 493 Query: 410 TYPYRNLKWEHYLEVINVLEDAGIIRREEGILKLGRRAFKYYFDNLSTIPDEVS--YKVV 467 T L E++ LE A ++RR RR +L+ I E +VV Sbjct: 494 TEEDLKLFGPACEELLPQLEAAKLLRRRTRAWHWTRRE---RAADLTDIRGEGGRPVQVV 550 Query: 468 DIGSGKVIGRLDENFV-MDLEEGMEFIMHGRSWLVLEIDGENLIIKVRES 516 + G+G+++G +D + EG + GR++LV +D E+ + V ++ Sbjct: 551 EEGTGRLLGTVDAGAAHTTVHEGAVHLHQGRTYLVRSLDLEDSVALVEQA 600 >gb|AAC00620.1| (AC002291) Similar ATP-dependent RNA Helicase [Arabidopsis thaliana] Length = 845 Score = 85.8 bits (209), Expect = 2e-15 Identities = 87/335 (25%), Positives = 148/335 (43%), Gaps = 20/335 (5%) Query: 8 AIKEK-FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP--IS 64 AIK+K ++ +Q + I G V+ +A TGSGKT A ++P++ LK +P + Sbjct: 42 AIKKKGYKVPTPIQRKTMPLILSGVDVVAMARTGSGKTAAFLIPMLEK-LKQHVPQGGVR 100 Query: 65 CLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLP 124 L ++P + L L+ K T +R+ + G + + +++ P V+I TP L Sbjct: 101 ALILSPTRDLAEQTLKFTKELGKFTDLRVSLLVGGDSMEDQFEELTKGPDVIIATPGRLM 160 Query: 125 ALLT-VKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 LL+ V + L+ V +VV DE L QL L +LS + + Sbjct: 161 HLLSEVDDMT--LRTVEYVVFDEADSLFGMGFAEQLHQILTQLSENRQTLLFSATLPSAL 218 Query: 184 EEEVKEWLGVDEIVKPPLKKRYK--FKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEI 241 E K L ++V+ ++ + K+ F RPE+K +A L + E Sbjct: 219 AEFAKAGLREPQLVRLDVENKISPDLKLSFLTVRPEEK-----------YSALLYLVREH 267 Query: 242 VEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALIC 301 + ++ L+FV+T+ E + K V +G + ++AR + + K LI Sbjct: 268 ISSDQQTLIFVSTKHHVEFVNSLFKLENIEPSVCYGDMDQDARKIHVSRFRARKTMLLIV 327 Query: 302 TSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 T GIDI +D VI + P + + R GR+ Sbjct: 328 TDIAARGIDIPLLDNVINWDFPPRPKIFVHRVGRA 362 >pir||D69772 ATP-dependent RNA helicase homolog ydbR - Bacillus subtilis >gi|1881268|dbj|BAA19295.1| (AB001488) ATP-DEPENDENT RNA HELICASE DEAD HOMOLOG. [Bacillus subtilis] >gi|2632758|emb|CAB12265.1| (Z99106) similar to ATP-dependent RNA helicase [Bacillus subtilis] Length = 511 Score = 85.4 bits (208), Expect = 2e-15 Identities = 80/340 (23%), Positives = 151/340 (43%), Gaps = 28/340 (8%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 L+K + F E +Q + K V+ A TG+GKT A +P++ I + P I Sbjct: 31 LMKAINRMGFEEATPIQAQTIPLGLSNKDVIGQAQTGTGKTAAFGIPLVEKINPES-PNI 89 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 + IAP + L + E L ++ +G R+ + ++ P++++ TP L Sbjct: 90 QAIVIAPTRELAIQVSEELYKIGQDKRAKVLPIYGGQDIGRQIRALKKNPNIIVGTPGRL 149 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 + +++R L NV VV+DE E+++ + I D + + + N Sbjct: 150 LDHINRRTIR--LNNVNTVVMDEADEMLN-------------MGFIDD-----IESILSN 189 Query: 184 EEEVKEWLGVDEIVKPPLKK---RYKFKVLFPRPRPEDKELAELLRVDVEVAARLR--TL 238 + L + P+K+ R+ + + + ++ ++ + + +EV R + TL Sbjct: 190 VPSEHQTLLFSATMPAPIKRIAERFMTEPEHVKVKAKEMTVSNIQQFYLEVQERKKFDTL 249 Query: 239 WEI--VEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKV 296 + ++ + +VF T++ + LA L G E HG L++ R+ A RK KEG + Sbjct: 250 TRLLDIQSPELAIVFGRTKRRVDELAEALNLRGYAAEGIHGDLTQAKRMVALRKFKEGAI 309 Query: 297 KALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 + L+ T G+DI V V + P+ + R GR+ Sbjct: 310 EVLVATDVAARGLDISGVTHVYNFDVPQDPESYVHRIGRT 349 >gb|AAF60892.1| (AC024876) contains similarity to SW:RPB1_CRIGR [Caenorhabditis elegans] Length = 875 Score = 85.0 bits (207), Expect = 3e-15 Identities = 92/392 (23%), Positives = 156/392 (39%), Gaps = 45/392 (11%) Query: 2 HILLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLP 61 H + K K+ F + +Q + I +GK V+ ++ TGSGKT A ++P++ + + Sbjct: 33 HSVYKAIEKKGFNQPTPIQRKTIPCIMDGKDVVAMSRTGSGKTAAFVIPMLQKLKRRDTT 92 Query: 62 PISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPE 121 I L ++P + L + +K TG+R G + + P +L+ TP Sbjct: 93 GIRALMVSPTRELALQTFKVVKELGRFTGLRCACLVGGDQIEEQFSTIHENPDILLATPG 152 Query: 122 TLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRL--------------S 167 L ++ LR L V++VV DE L + QL LKR+ Sbjct: 153 RLLHVIVEMDLR--LSYVQYVVFDEADRLFEMGFQDQLTETLKRIPESRQTLLFSATLPK 210 Query: 168 LIADFIRIGLSATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELA----- 222 ++ DF + GL+ + + L VDE V K ++F RP++K A Sbjct: 211 MLVDFAKAGLT------DPMLVRLDVDEKVSD------KLSMVFCMCRPDEKLFALLHLC 258 Query: 223 ------ELLRVDVEVAARLRTLWEIVEK------HKRVLVFVNTRQFAEVLAHRLKTWGK 270 +LL ++ + +++K +K+ +VF T + E + L G Sbjct: 259 RNFCFKKLLETSLKKCKISKKKVPLLKKVRMDRENKQTVVFCATMKHVEYVVGILHRAGI 318 Query: 271 PVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLI 330 + L AR +K E + L+ T G+DI +D VI P + + Sbjct: 319 DCSFVYSQLDATARKMNIQKFHEKQNNILVVTDVAARGVDIPLLDTVINLHFPPKAKLFV 378 Query: 331 QRAGRSKHRLLEVSEAYIIATGVEDYLQSLII 362 R GR + +IA YL L + Sbjct: 379 HRVGRVARAGRSGTAISLIANDELPYLTDLFM 410 >pir||H70414 conserved hypothetical protein aq_1328 - Aquifex aeolicus >gi|2983748|gb|AAC07309.1| (AE000734) hypothetical protein [Aquifex aeolicus] Length = 764 Score = 84.7 bits (206), Expect = 4e-15 Identities = 113/470 (24%), Positives = 219/470 (46%), Gaps = 86/470 (18%) Query: 16 LNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLKALN 75 LN +Q +K EG + L+ APT +GK+ A L + K+G+ ++ AP ++L Sbjct: 50 LNPIQTLFYKEY-EGGNALVSAPTSAGKSLTAFLFLRG---KEGIK----VFTAPTRSLV 101 Query: 76 RDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKSLRPY 135 + L+ K +++VR G+ + K++++ V++ T E+L L +++ + Sbjct: 102 YEKASELRELFRK---KVEVRTGEV--FELYKEIKS--EVVVATYESL--ALALRNRASW 152 Query: 136 LKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGNEEEVKEWLGVDE 195 ++ R VV+DE+ +L+ ++ ++ + L ++ +GLSAT+ E++ +W+ + Sbjct: 153 IEEARGVVIDEIHQLMGSR--GWILEEIITFLLDGNYEILGLSATLPGAEQLAKWIKAEL 210 Query: 196 IVKP-----PLKKR----YKFK--VLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEK 244 ++ PL+++ KF+ P+ +D+++A L L L+ + + Sbjct: 211 FIESRWRPVPLERKIIPLIKFEEFTKLPKGATQDEKIANKL---------LGALYTLKKP 261 Query: 245 HKRVLVFVNTRQF---AEVLAHRLKTW------------GKPVEV--HHGSLSKEARIEA 287 ++V++FV+ + +A+R K + VE+ H+ + KE R E Sbjct: 262 DEQVILFVHKKSVGWNVLEIANREKIGIMNETTPFEKEEREEVELAFHNADVPKEERDEI 321 Query: 288 ERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMS-----PRQ------VNRLIQRAGRS 336 E+ +EGK+ L+ TS++ G+++ +I S RQ V ++Q GR+ Sbjct: 322 EKAFREGKLPVLVATSTLAYGVNLPADTVIISVRSFYDRERRQRKFFPDVLDILQMEGRA 381 Query: 337 -KHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIKPY-------ENALDVLAHFI 388 + + E +YI+ G ++ +AK E E KPY E L VL+ FI Sbjct: 382 GRLGIKEKGYSYILPYGAKEE----NLAKALSEKLKEEFKPYLREVFLSEEKLKVLSLFI 437 Query: 389 -VGLLIEYQKLNVHEPYRMAKETYPYRNLKWEHYL-EVINVLEDAGIIRR 436 VG L E + + + TY + L + + EV L+D G I + Sbjct: 438 LVGFLYEGENFR-----KFLERTYSLKELAYSPQIDEVYEWLKDKGYIEK 482 >dbj|BAB05104.1| (AP001511) ATP-dependent RNA helicase [Bacillus halodurans] Length = 438 Score = 84.3 bits (205), Expect = 6e-15 Identities = 85/332 (25%), Positives = 147/332 (43%), Gaps = 38/332 (11%) Query: 19 LQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLKALNRDL 78 +Q I GK V+ + TG+GKT A +LP+++ I + + + AP + L + Sbjct: 30 IQERLIPAIRNGKDVIGQSQTGTGKTLAFLLPIVDRI-EGEREEVQAVITAPTRELAGQI 88 Query: 79 LERL----KWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKSLRP 134 E L + IR + G T + R +++R P +++ TP + L+ ++L Sbjct: 89 FEELQALLRHVPHDEEIRAKLIVGGTDRSRTLEKLRVQPQIVVGTPGRISDLVHEQALNV 148 Query: 135 YLKNVRFVVVDEVTELID-------NKRGAQLILNLKRLSLIADFIRIGLSATVGNEEEV 187 Y + +VVDE +++D +K A++ NL+ + SAT+ Sbjct: 149 YTATM--LVVDEADQMLDMGFIEDVDKVAARMAENLQMMVF---------SATI------ 191 Query: 188 KEWLGVDEIVKPPLKKRYKF-KVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEKHK 246 E +KP LKK + + +P+ L E V + +L E+ Sbjct: 192 ------PEKLKPFLKKYMNEPRHVHVQPKQATANLIEHRIVPLRHRDKLEITTEVASVLN 245 Query: 247 RVL--VFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSS 304 L VF NT++ A+ LA + G VE HG L R + +++K +V+ L+ T Sbjct: 246 PFLAIVFTNTKEQADELADAMLAAGLNVERLHGGLQPRQRKQVMKRVKNYEVQYLVATDL 305 Query: 305 MELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 GIDI V +I Y P+ ++ + R GR+ Sbjct: 306 AARGIDIKGVSHIINYSLPKDLDFYVHRVGRT 337 >sp|Q64060|DDX4_RAT DEAD BOX PROTEIN 4 (VASA HOMOLOG) (RVLG) >gi|1083795|pir||JC2534 RVLG protein - rat >gi|806464|gb|AAB33364.1| (S75275) vasa-like gene protein, RVLG protein=putative DEAD box protein [rats, Wistar-Imanishi, testis, Peptide, 713 aa] [Rattus sp.] Length = 713 Score = 83.9 bits (204), Expect = 7e-15 Identities = 81/337 (24%), Positives = 150/337 (44%), Gaps = 20/337 (5%) Query: 10 KEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDG--------LP 61 K + +L +Q + + G+ ++ A TGSGKT A +LP++ +++DG L Sbjct: 290 KAGYTKLTPVQKYSIPIVLAGRDLMACAQTGSGKTAAFLLPILAHMMRDGITASRFKELQ 349 Query: 62 PISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPE 121 C+ +AP + L + + + T +R V +G T +Q+ ++L TP Sbjct: 350 EPECIIVAPTRELINQIYLEARKFSFGTCVRAVVIYGGTQFGHSIRQIVQGCNILCATPG 409 Query: 122 TLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATV 181 L ++ + + LK V+++V+DE ++D G ++ + + + R L + Sbjct: 410 RLMDIIGKEKIG--LKQVKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLLFSA 467 Query: 182 GNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEI 241 EE++ G LK Y F V + +++ + + + V + R L EI Sbjct: 468 TFPEEIQRLAGEF------LKSNYLF-VAVGQVGGACRDVQQSI-LQVGPVFKKRKLVEI 519 Query: 242 VEK--HKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKAL 299 + +R +VFV T++ A+ +A L HG + R +A + GK L Sbjct: 520 LRNIGDERPMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRCGKCPVL 579 Query: 300 ICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 + TS G+DI V VI + P ++ + R GR+ Sbjct: 580 VATSVAARGLDIENVQHVINFNLPSTIDEYVHRIGRT 616 >pir||F82295 ATP-dependent RNA helicase SrmB VC0660 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9655098|gb|AAF93826.1| (AE004152) ATP-dependent RNA helicase SrmB [Vibrio cholerae] Length = 423 Score = 83.5 bits (203), Expect = 1e-14 Identities = 85/340 (25%), Positives = 153/340 (45%), Gaps = 22/340 (6%) Query: 4 LLKKAIKEK-FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSIL---KDG 59 +L +AI+E F ++Q EA + +G+ VL APTG+GKT A ++P + +L + Sbjct: 13 ILLEAIEEMGFSRPTQVQAEAIPQALDGRDVLASAPTGTGKTAAFVIPALQYLLDFPRRK 72 Query: 60 LPPISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITT 119 P L + P + L + E+ + T + I G A + +++ T Sbjct: 73 AGPARILILTPTRELAMQVAEQAQALAKNTRLNIFTITGGVQYQEHADILATTQDIVVAT 132 Query: 120 PETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGL-- 177 P L L + + R + + ++++DE ++D G + RLS + + L Sbjct: 133 PGRL--LEYIDAERFDCRAIEWLILDEADRMLDMGFGP----TVDRLSTECRWRKQTLLF 186 Query: 178 SATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRT 237 SAT+ E GV+ LK V PR E K++++ ++ ++ Sbjct: 187 SATL-------EGRGVEGFTADLLKD--PAHVDAEPPRRERKKISQWYHRADDMPHKVEL 237 Query: 238 LWEIV-EKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKV 296 L +I+ E+ +R +VF+ TR+ L L+ P G + ++ R A + +EG V Sbjct: 238 LKKILTEQAERSIVFLKTRERLADLRAELEKAQIPCAWIQGEMPQDRRNNAISRFREGDV 297 Query: 297 KALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 L+ T GID+ ++ VI + PR + + R GR+ Sbjct: 298 NILLATDVAARGIDVPDISHVINFDLPRSADVYLHRIGRT 337 >pir||T00936 ATP-dependent RNA helicase homolog T24P15.18 - Arabidopsis thaliana >gi|2673917|gb|AAB88651.1| (AC002561) putative U5 small nuclear ribonucleoprotein-specific protein [Arabidopsis thaliana] Length = 2172 Score = 83.5 bits (203), Expect = 1e-14 Identities = 94/398 (23%), Positives = 178/398 (44%), Gaps = 88/398 (22%) Query: 14 RELNRLQIEAF-KRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP-------ISC 65 ++LNR+Q + + + + ++L+ APTG+GKT A+L +++ + + P Sbjct: 504 QQLNRVQSKVYGTALFKADNILLCAPTGAGKTNVAVLTILHQLGLNMNPGGTFNHGNYKI 563 Query: 66 LYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPA 125 +Y+AP+KAL ++++ L G+ + GD Q ++++ +++TTPE Sbjct: 564 VYVAPMKALVAEVVDSLSQRLKDFGVTVKELSGD--QSLTGQEIKET-QIIVTTPEKWDI 620 Query: 126 LLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQL----ILNLKRLSLIADFIR-IGLSAT 180 + R Y + VR +++DE+ L+D+ RG L L+++ + IR +GLSAT Sbjct: 621 ITRKSGDRTYTQLVRLLIIDEI-HLLDDNRGPVLESIVARTLRQIESTKEHIRLVGLSAT 679 Query: 181 VGNEEEVKEWLGVD-----------------------EIVKPPLKK-------------- 203 + N ++V +L VD VK PL++ Sbjct: 680 LPNCDDVASFLRVDLKNGLFIFDRSYRPVPLGQQYIGINVKKPLRRFQLMNDICYQKVVA 739 Query: 204 -RYKFKVL-FPRPRPEDKELAELLRVDVEVAARLRTLWEIVEKHKRVLVFVNTRQFAEVL 261 K +VL F R E + A +R + A TL +++ + +R+ + L Sbjct: 740 VAGKHQVLIFVHSRKETAKTARAIR---DTAMANDTLSRFLKEDSQ------SREILKCL 790 Query: 262 AHRLKT--------WGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGE 313 A LK +G +HH L++ R E + + G ++ LI T+++ G+++ Sbjct: 791 AGLLKNNDLKELLPYG--FAIHHAGLTRTDREIVENQFRWGNLQVLISTATLAWGVNLPA 848 Query: 314 VDAVIQ-------------YMSPRQVNRLIQRAGRSKH 338 +I+ +SP V ++I RAGR ++ Sbjct: 849 HTVIIKGTQVYNPERGEWMELSPLDVMQMIGRAGRPQY 886 Score = 76.1 bits (184), Expect = 2e-12 Identities = 70/271 (25%), Positives = 130/271 (47%), Gaps = 28/271 (10%) Query: 7 KAIKEKFRELNRLQIEAFKRI-SEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISC 65 + + + F+ N +Q + F + + +V++ APTGSGKT A ++ + L+ + Sbjct: 1343 ETLYQDFKHFNPVQTQVFTVLYNTSDNVVVAAPTGSGKTICAEFAILRNHLEGPDSAMRV 1402 Query: 66 LYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTT-QYRRAKQVRNPPHVLITTPETLP 124 +YIAPL+A+ + E+ + WE K G + +R + T + ++ ++I+TPE Sbjct: 1403 VYIAPLEAIAK---EQFRDWEKKFGKGLGLRVVELTGETLLDLKLLEKGQIIISTPEKWD 1459 Query: 125 ALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRL----SLIADFIRI-GLSA 179 AL R Y++ V +VDE+ LI + G L + + R+ S + + IRI LS Sbjct: 1460 ALSRRWKQRKYIQQVSLFIVDEL-HLIGGQGGQVLEVIVSRMRYISSQVGNKIRIVALST 1518 Query: 180 TVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKEL----AELLRVDVEVAARL 235 ++ N +++ EW+G + F P RP E+ ++L + + A Sbjct: 1519 SLANAKDLGEWIGASSC------GVFNFP---PNVRPVPLEIHIHGVDILSFEARMQAMT 1569 Query: 236 RTLWEIVEKH----KRVLVFVNTRQFAEVLA 262 + + + +H K +VFV TR+ + A Sbjct: 1570 KPTYTAIVQHAKNKKPAIVFVPTRKHVRLTA 1600 >pir||E82488 ATP-dependent RNA helicase RhlE VCA0204 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9657596|gb|AAF96116.1| (AE004360) ATP-dependent RNA helicase RhlE [Vibrio cholerae] Length = 451 Score = 83.1 bits (202), Expect = 1e-14 Identities = 91/379 (24%), Positives = 161/379 (42%), Gaps = 34/379 (8%) Query: 7 KAIKEK-FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKD---GLPP 62 KAI+EK + + +Q++A + GK V+ A TG+GKT LP++ + K Sbjct: 14 KAIEEKGYNTPSPIQLQAIPAVLAGKDVMAAAQTGTGKTAGFTLPILELLAKGPKVRANQ 73 Query: 63 ISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPET 122 + L + P + L + + + + ++ V G + +++ +L+ TP Sbjct: 74 VRALILTPTRELAAQIQDNVMLYGRHLPLKSAVVFGGVKINPQMQRMCKGADILVATPGR 133 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNK--RGAQLILNL---KRLSLIADFIRIGL 177 L L +++ + +V+DE ++D R IL L KR +L+ Sbjct: 134 LMDLYNQNAVK--FDQLEILVLDEADRMLDMGFIRDIHKILKLLPEKRQNLL-------F 184 Query: 178 SATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRT 237 SAT E + E+ K + + V P E +V + Sbjct: 185 SATFSTE--------IRELAKGLVNNPVEISV---SPANSTARTVEQCIYPADVKKKPDM 233 Query: 238 LWEIVEK--HKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGK 295 L ++V++ ++VLVF+ T+ A LA L G HG+ S+ AR A K G+ Sbjct: 234 LVKLVKEGNWQQVLVFMRTKHGANRLATYLNEQGLTAAAIHGNKSQGARTRALADFKAGE 293 Query: 296 VKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVED 355 V+ L+ T GIDI ++ V+ + P+ + R GR+ R EV +A + + +E Sbjct: 294 VRILVATDIAARGIDIPQLPQVVNFELPKIAEDYVHRIGRT-GRAGEVGKAISLVSAIE- 351 Query: 356 YLQSLIIAKRAIEGKLERI 374 L +R + L R+ Sbjct: 352 -APELFAIERLTQALLPRV 369 >pir||T40504 atp-dependent, dead box, rna helicase - fission yeast (Schizosaccharomyces pombe) >gi|3560140|emb|CAA20727.1| (AL031534) atp-dependent, dead box, rna helicase [Schizosaccharomyces pombe] Length = 648 Score = 82.7 bits (201), Expect = 2e-14 Identities = 78/348 (22%), Positives = 147/348 (41%), Gaps = 15/348 (4%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKD-GLPP 62 +L K F + +Q S G ++ A TGSGKT A +P++ L++ Sbjct: 133 MLGSLSKAGFSKPMPIQSLVIPEASIGFDIIGKADTGSGKTLAFGIPILEHCLRNVDAKY 192 Query: 63 ISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPET 122 + L +AP + L + + + + IR+ G ++ + + PHV++ TP Sbjct: 193 VQALVVAPTRELAHQICQHFELIKPSPNIRVMSITGGLAVQKQQRLLNKHPHVVVATPGR 252 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQL--ILNLKRLSLIADFIRIGLSAT 180 L +++ +L K ++ +V+DE L+ +L +L + + SAT Sbjct: 253 LWSVINENNLTGNFKKIKCLVLDEADRLLQKSHFEELSKLLEILGNPMHTQRQTFIFSAT 312 Query: 181 V--GNEEEVKEWL--GVDEIVKPPLKKRYKFKVLFPRPR-----PEDKELAELLRVDVEV 231 G ++ +K+ + + E P++ K F +P+ P+ + +L +E Sbjct: 313 FDEGLQQRLKKNMKGNITEKYNSPMENMLKEVRFFGKPKFLDANPQSAVASRVLEGLIEC 372 Query: 232 AARLRTLWE---IVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAE 288 A + L+ I+ + +VF N + + + L P H L ++ R+++ Sbjct: 373 APAEKDLYLYYLIMRYPGKTMVFANGIEDIKRITPFLNELKVPSYPLHAQLDQKKRLQSL 432 Query: 289 RKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 K K L+CT GIDI V VI Y P + + R+GR+ Sbjct: 433 EKFKNNPKGVLVCTDVAARGIDIPSVTHVIHYHVPHTADMYVHRSGRT 480 >pir||T27149 hypothetical protein Y54E2A.6 - Caenorhabditis elegans >gi|3881104|emb|CAA21682.1| (AL032646) contains similarity to Pfam domain: PF00270 (DEAD/DEAH box helicase), Score=243.2, E-value=1.9e-76, N=2~cDNA EST CEMSC91F comes from this gene~cDNA EST yk36e11.3 comes from this gene~cDNA EST yk42a9.3 comes from this gene~cDNA EST yk42a9.5 c> Length = 1798 Score = 82.3 bits (200), Expect = 2e-14 Identities = 101/352 (28%), Positives = 150/352 (41%), Gaps = 72/352 (20%) Query: 13 FRELNRLQIEAFKRISE-GKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPL 71 F N +Q + F + + KS LI APTGSGKT A L M +L+D P + +YIAPL Sbjct: 958 FDYFNPIQAQVFFCLYKTDKSALIGAPTGSGKTLCAEL-AMFRLLQDH-PGMKVVYIAPL 1015 Query: 72 KALNRDLLERLKWWEAK----TGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALL 127 K+L R ER+ W+ K G R+ GD T + +LITTPE + Sbjct: 1016 KSLVR---ERVDDWKKKFEDGMGYRVVEVSGDVTPDPEELAASS---ILITTPEKWDGIS 1069 Query: 128 TVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIA-------DFIR-IGLSA 179 + R Y++ V +V+DEV L+ RGA L + RL +I + +R +GLS Sbjct: 1070 RSWATREYVRRVGLIVLDEV-HLLGVDRGAVLEAIVSRLKMITRRSHVTEEPVRLLGLST 1128 Query: 180 TVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLW 239 + N +V EWLG+ P + Y F+ P RP + R+ + Sbjct: 1129 ALANAGDVAEWLGI------PDEACYNFR---PSVRPVPISVHIQGFPGQHYCPRMGLMN 1179 Query: 240 EIVEK-------HKRVLVFVNTRQFAEVLA----------HRLKTWGK------------ 270 + K K VL+FV++R+ + A H K W Sbjct: 1180 KPAYKAILTYSPRKPVLIFVSSRRQTRLTALAFVNLLIADHNPKQWLNMDMLELEDLMAA 1239 Query: 271 ------------PVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGID 310 + +HH LS R E+ E K++ LI T+++ GI+ Sbjct: 1240 IKDENLKLTLPFGIGMHHAGLSAHERAIVEQLFIEKKIQVLIATATLAWGIN 1291 >pir||C64440 DNA repair protein RAD24 homolog (intein-containing) - Methanococcus jannaschii >gi|1499976|gb|AAB99126.1| (U67555) putative SKI2-family helicase [Methanococcus jannaschii] Length = 1195 Score = 82.3 bits (200), Expect = 2e-14 Identities = 82/257 (31%), Positives = 126/257 (48%), Gaps = 16/257 (6%) Query: 15 ELNRLQIEAFKR--ISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISC--LYIAP 70 EL Q +A +R + + K+ LI PT SGKT + ++N +L P + ++I P Sbjct: 15 ELRPPQKKALERGLLDKNKNFLISIPTASGKTLIGEMALINHLLDGNKNPTNKKGIFIVP 74 Query: 71 LKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVK 130 LKAL + E K + G+RI + GD + + H++ITT E L +L K Sbjct: 75 LKALASEKYEEFKSKYERYGLRIALSIGDYDEDEDLSKY----HLIITTAEKLDSLWRHK 130 Query: 131 SLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGNEEEVKEW 190 ++ +V VVVDE+ + D RG L + L +L I IGLSAT+GN +E+ EW Sbjct: 131 I--DWINDVSVVVVDEIHLINDETRGGTLEILLTKLKEFNVQI-IGLSATIGNPDELAEW 187 Query: 191 LGVDEIVKPPLKKRYKFKVLFPRPRPE--DKELAELLRVDVEVAARLRTLWEIVEKHKRV 248 L + IV K K ++ E + E+ E+ VD L + + V++ Sbjct: 188 LNAELIVDDWRPVELK-KGIYKNEAIEFINGEIREIKAVDNNDIYNL--VVDCVKEGGCC 244 Query: 249 LVFVNTRQFAEVLAHRL 265 LVF NT++ A A +L Sbjct: 245 LVFCNTKRNAVNEAKKL 261 >pir||I51235 DEAD box protein - African clawed frog (fragment) >gi|2896107|gb|AAC03114.1| (AF046043) DEAD box protein [Xenopus laevis] Length = 700 Score = 82.3 bits (200), Expect = 2e-14 Identities = 76/343 (22%), Positives = 154/343 (44%), Gaps = 20/343 (5%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDG---- 59 L + + + +L +Q + I G+ ++ A TGSGKT A +LP+++ ++ +G Sbjct: 285 LRRNVARAGYVKLTPVQKHSIPIIMAGRDLMACAQTGSGKTAAFLLPILSYMMNEGITAS 344 Query: 60 ----LPPISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHV 115 L + IAP + L + + + T +R V +G + V ++ Sbjct: 345 QYLQLQEPEAIIIAPTRELINQIYLDARKFSYGTCVRPVVVYGGIQPVHAMRDVEKGCNI 404 Query: 116 LITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRI 175 L TP L +++ + + L +R++V+DE ++D ++ + + + R Sbjct: 405 LCATPGRLLDIVSKEKIG--LSKLRYLVLDEADRMLDMGFAPEIEKLMTKPGMPTKEKRQ 462 Query: 176 GLSATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARL 235 L + EE++ + LK + F V+ ++A+ + +++ ++ Sbjct: 463 TLMFSATYPEEIRR------LASNYLKSEHLF-VVVGLVGGACSDVAQTV-LEMRENGKM 514 Query: 236 RTLWEIVE--KHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKE 293 L EI++ + +R ++FVNT++ A+ +A L HG + R A + Sbjct: 515 EKLLEILKSSEKERTMIFVNTKKKADFIAGYLCQEKFSSTSIHGDREQYQRESALWDFRT 574 Query: 294 GKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 GK ++CT+ G+DI V VI Y P++V+ + R GR+ Sbjct: 575 GKCTVIVCTAVAARGLDIENVQHVINYDVPKEVDEYVHRIGRT 617 >dbj|BAB14698.1| (AK023840) unnamed protein product [Homo sapiens] Length = 774 Score = 81.9 bits (199), Expect = 3e-14 Identities = 101/431 (23%), Positives = 195/431 (44%), Gaps = 83/431 (19%) Query: 11 EKFRELNRLQIEAFKRISE-GKSVLIIAPTGSGKTEAAILPVMNSILK----DG---LPP 62 E F+ LNR+Q + ++ E +++L+ APTG+GKT A++ ++ I K DG + Sbjct: 151 EGFKTLNRIQSKLYRAALETAENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDD 210 Query: 63 ISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPET 122 +YIAP+++L ++++ A GI + GD ++ +K+ + +++ TPE Sbjct: 211 FKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGD---HQLSKEEISATQIIVCTPEK 267 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRG----AQLILNLKRLSLIADFIR-IGL 177 + R Y + VR +++DE+ L+ + RG A + ++ + + + +R IGL Sbjct: 268 WDIITRKGGERTYTQLVRLIILDEI-HLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGL 326 Query: 178 SATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRT 237 SAT+ N E+V +L VD P K + F F RP P ++ + + + R + Sbjct: 327 SATLPNYEDVATFLRVD-----PAKGLFYFDNSF-RPVPLERTYVGI--TEKKAIKRFQI 378 Query: 238 LWEIVEK-------HKRVLVFVNTRQFAEVLAHRLK-------TWG-------------- 269 + EIV + +VLVFV++R+ A ++ T G Sbjct: 379 MNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLR 438 Query: 270 ------KPVE----------VHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGE 313 K +E +HH +++ R E + ++ L+ T+++ G+++ Sbjct: 439 TEAEQCKNLELKDLLLYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPA 498 Query: 314 VDAVI---QYMSPRQ----------VNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSL 360 +I Q SP + + +++ RAGR ++ + I + G Y SL Sbjct: 499 HTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYD-TKGEGILITSHGELQYYLSL 557 Query: 361 IIAKRAIEGKL 371 + + IE ++ Sbjct: 558 LNQQLPIESQM 568 >sp|Q40470|IF47_TOBAC EUKARYOTIC INITIATION FACTOR 4A-7 (EIF-4A-7) (EIF4A-7) >gi|485949|emb|CAA55738.1| (X79137) NeIF-4A7 [Nicotiana tabacum] Length = 413 Score = 81.5 bits (198), Expect = 4e-14 Identities = 80/338 (23%), Positives = 149/338 (43%), Gaps = 23/338 (6%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q +G V+ A +G+GKT V+ L L Sbjct: 51 LLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGVLQQ-LDYSLVEC 109 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L +AP + L + + + ++ G+++ G T+ + +++ HV++ TP + Sbjct: 110 QALVLAPTRELAQQIEKVMRALGDYLGVKVHACVGGTSVREDQRILQSGVHVVVGTPGRV 169 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 +L +SLRP +++ V+DE E++ Q+ L+ I++G+ + Sbjct: 170 FDMLRRQSLRP--DHIKMFVLDEADEMLSRGFKDQIY---DIFQLLPPKIQVGVFSATMP 224 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA---RLRTLWE 240 E + EI + + K + V + +D L + + V V +L TL + Sbjct: 225 PEAL-------EITRKFMNKPVRILV-----KRDDVTLEGIKQFYVNVDKEEWKLETLCD 272 Query: 241 IVEKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKA 298 + E + ++FVNTR+ + L +++T V HG + + R R+ + G + Sbjct: 273 LYETLAITQSVIFVNTRRKVDWLTDKMRTRDHTVSATHGDMDQNTRDIIMREFRSGSSRV 332 Query: 299 LICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 LI T + GID+ +V VI Y P Q + R GRS Sbjct: 333 LITTDLLARGIDVQQVSLVINYDLPTQPENYLHRIGRS 370 >gb|AAB03337.1| (U60194) RNA helicase GLH-2 [Caenorhabditis elegans] >gi|1405387|gb|AAB03510.1| (U60449) GLH-2 [Caenorhabditis elegans] Length = 974 Score = 81.5 bits (198), Expect = 4e-14 Identities = 84/331 (25%), Positives = 139/331 (41%), Gaps = 29/331 (8%) Query: 27 ISEGKSVLIIAPTGSGKTEAAILPVMNSILKD---------GLPPISCLYIAPLKALNRD 77 I +G ++ A TGSGKT A +LP+M ++ + G P C+ + P + L Sbjct: 586 IHQGHDIMACAQTGSGKTAAFLLPIMARLIDENDLNTAGEGGCYP-RCIILTPTRELTDQ 644 Query: 78 LLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKSLRPYLK 137 + + + +T + I +G Q+ +++ T + +++ L Sbjct: 645 IYNEGRKFAYQTMMEIRPVYGGLAVGYNKGQIEKGATIIVGTVGRIKHFCEEGTIK--LD 702 Query: 138 NVRFVVVDEVTELID------------NKRGAQLILNLKRLSLIADFIRIGLSATVGNEE 185 RF V+DE +ID N N + L A F A + + Sbjct: 703 KCRFFVLDEADRMIDAMGFGTDIDTIVNYESMPKKENRQTLMFSATFPDSVQEAARNHLK 762 Query: 186 EVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEKH 245 E L +D+I +F+ R +DK L E+L +D++ + E+ K Sbjct: 763 EGYIMLAIDKIGAANKCVLQEFEKC-DRSEKKDK-LLEILGIDIDSYTTEKNS-EVYTK- 818 Query: 246 KRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSM 305 + +VFV+ R A+ LA L + P HG+ + R EA R+ + G LI T+ Sbjct: 819 -KTIVFVSQRAMADTLASILSSAQVPAITIHGAREQRERSEALRQFRNGSKPVLIATAVA 877 Query: 306 ELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 E G+DI VD VI Y P ++ I R GR+ Sbjct: 878 ERGLDIKGVDHVINYDMPDNIDDYIHRIGRT 908 >gb|AAF55204.1| (AE003709) CG5205 gene product [Drosophila melanogaster] Length = 1809 Score = 81.1 bits (197), Expect = 5e-14 Identities = 88/353 (24%), Positives = 163/353 (45%), Gaps = 55/353 (15%) Query: 5 LKKAIKE---KFRELNRLQIEAFKRISE-GKSVLIIAPTGSGKTEAAILPVMNSILKDGL 60 LK + E KF N +Q + F + +VL+ APTGSGKT A + + ++ ++ Sbjct: 949 LKNVVYESLYKFTHFNPIQTQIFHCLYHTDNNVLLGAPTGSGKTIVAEIAIFRALNQN-- 1006 Query: 61 PPISCLYIAPLKALNRDLLERLKWWEAK-----TGIRIDVRHGDTTQYRRAKQVRNPPHV 115 P +YIAPLKAL + ER+ WE + G+++ GD T +A + + Sbjct: 1007 PKCKVVYIAPLKALVK---ERIADWEQRFQRSSLGLKVVELTGDVTPDIQAIR---ESQL 1060 Query: 116 LITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADF--- 172 ++TTPE + R Y+++V +V+DE+ L+ RG + + + R + I+ Sbjct: 1061 IVTTPEKWDGISRSWQTREYVQHVSLIVIDEI-HLLGEDRGPVIEVIVSRTNFISSHTGR 1119 Query: 173 -IRI-GLSATVGNEEEVKEWLGVDEI--------VKP-PLK---KRYKFKVLFPRPRPED 218 IRI GLS + N +++ WLG++++ V+P PL+ + K PR + Sbjct: 1120 AIRIVGLSTALANAQDLANWLGINKMGLYNFKPSVRPVPLQVHINGFPGKHYCPRMATMN 1179 Query: 219 KELAELLR-------VDVEVAARLRTLWEIVEKHKRVLVFVNTRQF-------AEVLAHR 264 + + +R V V++R +T ++ V N +QF E++ Sbjct: 1180 RPTFQAIRTYSPCEPTIVFVSSRRQTRLTALDLITFVAGESNPKQFLHIPEDEIELILQN 1239 Query: 265 LKTWGKP------VEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDI 311 ++ + +HH L ++ R E K++ L+ T+++ G+++ Sbjct: 1240 IREQNLKFCLAFGIGLHHAGLQEQDRKCVEELFLNRKIQILVATATLAWGVNL 1292 >gb|AAB64289.1| (AF007580) translation initiation factor [Zea mays] Length = 414 Score = 81.1 bits (197), Expect = 5e-14 Identities = 79/338 (23%), Positives = 150/338 (44%), Gaps = 23/338 (6%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ + F + + +Q +G V+ A +G+GKT ++ L GL Sbjct: 52 LLRGIYRYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGILQQ-LDYGLVEC 110 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L +AP + L + + + ++ G+++ G T+ + + + HV++ TP + Sbjct: 111 QALVLAPTRELAQQIEKVMRALGDYLGVKVHACVGGTSVREDQRILGSGVHVVVGTPGRV 170 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 +L +SLRP N++ V+DE E++ Q+ L+ I++G+ + Sbjct: 171 FDMLRRQSLRP--DNIKMFVLDEADEMLSRGFKDQIY---DIFQLLPAKIQVGVFSATMP 225 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA---RLRTLWE 240 E + EI + + K + V + ++ L + + V V +L TL + Sbjct: 226 PEAL-------EITRKFMNKPVRILV-----KRDELTLEGIKQFYVNVDKEDWKLDTLCD 273 Query: 241 IVEKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKA 298 + E + ++FVNTR+ + L ++++ V HG + + R R+ + G + Sbjct: 274 LYETLAITQSVIFVNTRRKVDWLTDKMRSRDHTVSATHGDMDQNTRDIIMREFRSGSSRV 333 Query: 299 LICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 LI T + GID+ +V VI Y P Q + R GRS Sbjct: 334 LITTDLLARGIDVQQVSLVINYDLPTQPENYLHRIGRS 371 >gb|AAB67607.1| (U73459) translational initiation factor eIF-4A [Zea mays] Length = 414 Score = 81.1 bits (197), Expect = 5e-14 Identities = 79/338 (23%), Positives = 149/338 (43%), Gaps = 23/338 (6%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q +G V+ A +G+GKT ++ L GL Sbjct: 52 LLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGILQQ-LDYGLVEC 110 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L +AP + L + + + ++ G+++ G T+ + + + HV++ TP + Sbjct: 111 QALVLAPTRELAQQIEKVMRALGDYLGVKVHACVGGTSVREDQRILASGVHVVVGTPGRV 170 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 +L +SLRP N++ V+DE E++ Q+ L+ I++G+ + Sbjct: 171 FDMLRRQSLRP--DNIKMFVLDEADEMLSRGFKDQIY---DIFQLLPSKIQVGVFSATMP 225 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA---RLRTLWE 240 E + EI + + K + V + ++ L + + V V +L TL + Sbjct: 226 PEAL-------EITRKFMNKPVRILV-----KRDELTLEGIKQFYVNVDKEDWKLDTLCD 273 Query: 241 IVEKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKA 298 + E + ++FVNTR+ + L ++++ V HG + + R R+ + G + Sbjct: 274 LYETLAITQSVIFVNTRRKVDWLTDKMRSRDHTVSATHGDMDQNTRDIIMREFRSGSSRV 333 Query: 299 LICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 LI T + GID+ +V VI Y P Q + R GRS Sbjct: 334 LITTDLLARGIDVQQVSLVINYDLPTQPENYLHRIGRS 371 >dbj|BAB14906.1| (AK024391) unnamed protein product [Homo sapiens] Length = 1811 Score = 80.8 bits (196), Expect = 6e-14 Identities = 101/431 (23%), Positives = 194/431 (44%), Gaps = 83/431 (19%) Query: 11 EKFRELNRLQIEAFKRISE-GKSVLIIAPTGSGKTEAAILPVMNSILK----DG---LPP 62 E F+ LNR+Q + ++ E +++L+ APTG+GKT A++ ++ I K DG + Sbjct: 151 EGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDD 210 Query: 63 ISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPET 122 +YIAP+++L ++++ A GI + GD ++ K+ + +++ TPE Sbjct: 211 FKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGD---HQLCKEEISATQIIVCTPEK 267 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRG----AQLILNLKRLSLIADFIR-IGL 177 + R Y + VR +++DE+ L+ + RG A + ++ + + + +R IGL Sbjct: 268 WDIITRKGGERTYTQLVRLIILDEI-HLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGL 326 Query: 178 SATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRT 237 SAT+ N E+V +L VD P K + F F RP P ++ + + + R + Sbjct: 327 SATLPNYEDVATFLRVD-----PAKGLFYFDNSF-RPVPLEQTYVGI--TEKKAIKRFQI 378 Query: 238 LWEIVEK-------HKRVLVFVNTRQFAEVLAHRLK-------TWG-------------- 269 + EIV + +VLVFV++R+ A ++ T G Sbjct: 379 MNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLR 438 Query: 270 ------KPVE----------VHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGE 313 K +E +HH +++ R E + ++ L+ T+++ G+++ Sbjct: 439 TEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPA 498 Query: 314 VDAVI---QYMSPRQ----------VNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSL 360 +I Q SP + + +++ RAGR ++ + I + G Y SL Sbjct: 499 HTVIIKGTQVYSPEKGHWTELGALDILQMLGRAGRPQYD-TKGEGILITSHGELQYYLSL 557 Query: 361 IIAKRAIEGKL 371 + + IE ++ Sbjct: 558 LNQQLPIESQM 568 >emb|CAA94089.1| (Z70200) U5 snRNP-specific 200kD protein [Homo sapiens] Length = 1701 Score = 80.8 bits (196), Expect = 6e-14 Identities = 102/431 (23%), Positives = 194/431 (44%), Gaps = 83/431 (19%) Query: 11 EKFRELNRLQIEAFKRISE-GKSVLIIAPTGSGKTEAAILPVMNSILK----DG---LPP 62 E F+ LNR+Q + ++ E +++L+ APTG+GKT A++ ++ I K DG + Sbjct: 41 EGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDD 100 Query: 63 ISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPET 122 +YIAP+++L ++++ A GI + GD ++ K+ + +++ TPE Sbjct: 101 FKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGD---HQLCKEEISATQIIVCTPEK 157 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRG----AQLILNLKRLSLIADFIR-IGL 177 + R Y + VR +V+DE+ L+ + RG A + ++ + + + +R IGL Sbjct: 158 WDIITRKGGERTYTQLVRLIVLDEI-HLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGL 216 Query: 178 SATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRT 237 SAT+ N E+V +L VD P K + F F RP P ++ + + + R + Sbjct: 217 SATLPNYEDVATFLRVD-----PAKGLFYFDNSF-RPVPLEQTYVGI--TEKKAIKRFQI 268 Query: 238 LWEIVEK-------HKRVLVFVNTRQFAEVLAHRLK-------TWG-------------- 269 + EIV + +VLVFV++R+ A ++ T G Sbjct: 269 MNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLR 328 Query: 270 ------KPVE----------VHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGE 313 K +E +HH +++ R E + ++ L+ T+++ G+++ Sbjct: 329 TEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFGDKHIQVLVSTATLAWGVNLPA 388 Query: 314 VDAVI---QYMSPRQ----------VNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSL 360 +I Q SP + + +++ RAGR ++ + I + G Y SL Sbjct: 389 HTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYD-TKGEGILITSHGELQYYLSL 447 Query: 361 IIAKRAIEGKL 371 + + IE ++ Sbjct: 448 LNQQLPIESQM 458 >sp|Q41741|IF4A_MAIZE EUKARYOTIC INITIATION FACTOR 4A (EIF-4A) (EIF4A) >gi|603190|gb|AAA82736.1| (U17979) translation initiation factor eIF-4A [Zea mays] Length = 410 Score = 80.8 bits (196), Expect = 6e-14 Identities = 78/338 (23%), Positives = 149/338 (44%), Gaps = 23/338 (6%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q +G V+ A +G+GKT ++ L GL Sbjct: 48 LLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGILQQ-LDYGLVEC 106 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L +AP + L + + + ++ G+++ G T+ + + + HV++ TP + Sbjct: 107 QALVLAPTRELAQQIEKVMRALGDYLGVKVHACVGGTSVREDQRILASGVHVVVGTPGRV 166 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 +L +SLRP N++ V+DE E++ Q+ L+ I++G+ + Sbjct: 167 FDMLRRQSLRP--DNIKMFVLDEADEMLSRGFKDQIY---DIFQLLPSKIQVGVFSATMP 221 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA---RLRTLWE 240 E + EI + + K + V + ++ L + + V + +L TL + Sbjct: 222 PEAL-------EITRKFMNKPVRILV-----KRDELTLEGIKQFYVNIDKEDWKLDTLCD 269 Query: 241 IVEKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKA 298 + E + ++FVNTR+ + L ++++ V HG + + R R+ + G + Sbjct: 270 LYETLAITQSVIFVNTRRKVDWLTDKMRSRDHTVSATHGDMDQNTRDIIMREFRSGSSRV 329 Query: 299 LICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 LI T + GID+ +V VI Y P Q + R GRS Sbjct: 330 LITTDLLARGIDVQQVSLVINYDLPTQPENYLHRIGRS 367 >pir||S52019 translation initiation factor eIF-4A.7 - common tobacco Length = 413 Score = 80.8 bits (196), Expect = 6e-14 Identities = 80/336 (23%), Positives = 150/336 (43%), Gaps = 19/336 (5%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q +G V+ A +G+GKT V+ L L Sbjct: 51 LLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGVLQQ-LDYSLVEC 109 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L +AP + L + + + ++ G+++ G T+ + +++ HV++ TP + Sbjct: 110 QALVLAPTRELAQQIEKVMRALGDYLGVKVHACVGGTSVREDQRILQSGVHVVVGTPGRV 169 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 +L +SLRP +++ V+DE E++ Q+ L+ I++G+ + Sbjct: 170 FDMLRRQSLRP--DHIKMFVLDEADEMLSRGFKDQIY---DIFQLLPPKIQVGVFSATMP 224 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAEL-LRVDVEVAARLRTLWEIV 242 E + EI + + K ++L R + + + + VD E +L TL ++ Sbjct: 225 PEAL-------EITRKFMNK--PVRILVKRDEVTLEGIKQFYVNVDKE-EWKLETLCDLY 274 Query: 243 EKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALI 300 E + ++FVNTR+ + L +++T V HG + + R R+ + G + LI Sbjct: 275 ETLAITQSVIFVNTRRKVDWLTDKMRTRDHTVSATHGDMDQNTRDIIMREFRSGSSRVLI 334 Query: 301 CTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 T + GID+ +V VI Y P Q + R GRS Sbjct: 335 TTDLLARGIDVQQVSLVINYDLPTQPENYLHRIGRS 370 >gb|AAF39890.1| (AC006661) contains similarity to Pfam families PF00270 (DEAD/DEAH box helicase, score=162.5, E=1.8e-50, N=2) and PF00271 (Helicases conserved C-terminal domain, score=104.4, E=2.2e-27, N=1) [Caenorhabditis elegans] Length = 696 Score = 80.8 bits (196), Expect = 6e-14 Identities = 95/414 (22%), Positives = 170/414 (40%), Gaps = 65/414 (15%) Query: 4 LLKKAIK-EKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP 62 +LK +K KF R K+ +E K A TG+GKT A +P++ + D Sbjct: 159 ILKFPLKINKFSRKIRFFYRKIKKTTEEKCC---ARTGTGKTLAFAIPILQKLSVDPYG- 214 Query: 63 ISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPET 122 I L + P + L + E+ ++ V G + +A+++ PHV++ TP Sbjct: 215 IYALILTPTRELAFQIAEQFTALGKPITLKCSVIVGGRSLIHQARELSERPHVVVATPGR 274 Query: 123 LPALLTVK--SLRPYLKNVRFVVVDEVTELIDNKRGAQL-----ILNLKRLSLIADFIRI 175 L L+ ++ K ++F V+DE +++ + QL ++ KR +L+ Sbjct: 275 LADLIESDPDTIAKVFKKIQFFVLDEADRMLEGQYNDQLKPIFESISEKRQTLL------ 328 Query: 176 GLSATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLR---VDVEVA 232 LSAT+ N ++ + + +K Y F +D+ + L V VA Sbjct: 329 -LSATITNN--------INMLHRVSTRKPY----FFEDKGKDDESTVDRLEQKYVVCPVA 375 Query: 233 ARLRTLWEIVEKHKR------VLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIE 286 + L +V+ + V++F T + + LA+ + G V H + ++ R+ Sbjct: 376 VKDAYLVYVVKNYSEKNPKSSVMIFAQTCRECQALAYMFEGLGFRVGSLHSQIPQKQRLA 435 Query: 287 AERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKH-------- 338 A + ++ +ICT G+DI VD V+ + P+ I R GRS Sbjct: 436 ALSAFRSKTLQVIICTDVASRGLDIPHVDLVVNHNVPQCPKTYIHRVGRSARAGRFGSAL 495 Query: 339 --------RLLE---------VSEAYIIATGVEDYLQSLIIAKRAIEGKLERIK 375 LL+ + E + V Y+ +++AK+ E KLE K Sbjct: 496 SFVTQYDVELLQAVEQVIGKKLDELKVSPKHVTKYVTQVLVAKKEAELKLENQK 549 >gb|AAF53963.1| (AE003669) CG9253 gene product [Drosophila melanogaster] Length = 507 Score = 80.8 bits (196), Expect = 6e-14 Identities = 82/332 (24%), Positives = 148/332 (43%), Gaps = 27/332 (8%) Query: 12 KFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPL 71 K++ +++Q EA +GK V+ +A TGSGKT A LP+++++L++ + L + P Sbjct: 80 KWKAPSKIQREAIPVALQGKDVIGLAETGSGKTGAFALPILHALLENPQRYFA-LVLTPT 138 Query: 72 KALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKS 131 + L + E+ + + GI+ V G + Q+ PH++I TP L L ++ Sbjct: 139 RELAFQIGEQFEALGSGIGIKCCVVVGGMDMVAQGLQLAKKPHIIIATPGRLVDHL--EN 196 Query: 132 LRPY-LKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGNEEEVKEW 190 ++ + LK ++++V+DE +++ +L LK L + SAT+ + + + Sbjct: 197 MKGFNLKAIKYLVMDEADRILNMDFEVELDKILKVLP--RERRTFLFSATMTKKVKKLQR 254 Query: 191 LGVDEIVKPPLKKRYKF------KVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEK 244 + + VK + +Y+ LF + +D L +L E+A Sbjct: 255 ASLKDPVKVEVSNKYQTVEQLQQSYLFIPVKYKDVYLVHILN---ELAGN---------- 301 Query: 245 HKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSS 304 ++F +T A L+ G HG +S+ R+ A K K LI T Sbjct: 302 --SFMIFCSTCNNTVKTALMLRALGLAAIPLHGQMSQNKRLAALNKFKAKNRSILISTDV 359 Query: 305 MELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 G+DI VD V+ + P I R GR+ Sbjct: 360 ASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRT 391 >gb|AAA34666.1| (L00683) ATP-dependent RNA helicase [Saccharomyces cerevisiae] Length = 722 Score = 80.4 bits (195), Expect = 8e-14 Identities = 78/315 (24%), Positives = 144/315 (44%), Gaps = 20/315 (6%) Query: 30 GKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISC--LYIAPLKALNRDLLERLKWWEA 87 GK ++ A TGSGKT A ++P++ +L S + + P + L + + K Sbjct: 238 GKDIIAGAVTGSGKTAAFMIPIIERLLYKPAKIASTRVIVLLPTRELAIQVADVGKQIAR 297 Query: 88 -KTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKSLRPYLKNVRFVVVDE 146 +GI + G ++ + +++ P ++I TP + S + +V +V+DE Sbjct: 298 FVSGITFGLAVGGLNLRQQEQMLKSRPDIVIATPGRFIDHIR-NSASFNVDSVEILVMDE 356 Query: 147 VTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGNEEEVKEWLGVDEIVKPPLKKRYK 206 +++ G Q LN L ++ + SAT+ ++ + +V LKK + Sbjct: 357 ADRMLEE--GFQDELNEIMGLLPSNRQNLLFSATMNSK--------IKSLVSLSLKKPVR 406 Query: 207 FKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEK-----HKRVLVFVNTRQFAEVL 261 ++ P + K E +R+ + L+ ++ K KR++VFV ++ A L Sbjct: 407 I-MIDPPKKAATKLTQEFVRIRKRDHLKPALLFNLIRKLDPTGQKRIVVFVARKETAHRL 465 Query: 262 AHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYM 321 + G V HGSL++E R+++ K K +V LICT G+DI +++ VI Y Sbjct: 466 RIIMGLLGMSVGELHGSLTQEQRLDSVNKFKNLEVPVLICTDLASRGLDIPKIEVVINYD 525 Query: 322 SPRQVNRLIQRAGRS 336 P+ + R GR+ Sbjct: 526 MPKSYEIYLHRVGRT 540 >gi|6323021 putative ATP dependent RNA helicase; Drs1p [Saccharomyces cerevisiae] >gi|1706521|sp|P32892|DRS1_YEAST PROBABLE ATP-DEPENDENT RNA HELICASE DRS1 >gi|2132405|pir||S64750 probable ATP-dependent RNA helicase DRS1 - yeast (Saccharomyces cerevisiae) >gi|1360171|emb|CAA97452.1| (Z73113) ORF YLL008w [Saccharomyces cerevisiae] >gi|1495215|emb|CAA62783.1| (X91488) L1345/DRS1 protein [Saccharomyces cerevisiae] Length = 752 Score = 80.4 bits (195), Expect = 8e-14 Identities = 78/315 (24%), Positives = 144/315 (44%), Gaps = 20/315 (6%) Query: 30 GKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISC--LYIAPLKALNRDLLERLKWWEA 87 GK ++ A TGSGKT A ++P++ +L S + + P + L + + K Sbjct: 268 GKDIIAGAVTGSGKTAAFMIPIIERLLYKPAKIASTRVIVLLPTRELAIQVADVGKQIAR 327 Query: 88 -KTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKSLRPYLKNVRFVVVDE 146 +GI + G ++ + +++ P ++I TP + S + +V +V+DE Sbjct: 328 FVSGITFGLAVGGLNLRQQEQMLKSRPDIVIATPGRFIDHIR-NSASFNVDSVEILVMDE 386 Query: 147 VTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGNEEEVKEWLGVDEIVKPPLKKRYK 206 +++ G Q LN L ++ + SAT+ ++ + +V LKK + Sbjct: 387 ADRMLEE--GFQDELNEIMGLLPSNRQNLLFSATMNSK--------IKSLVSLSLKKPVR 436 Query: 207 FKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEK-----HKRVLVFVNTRQFAEVL 261 ++ P + K E +R+ + L+ ++ K KR++VFV ++ A L Sbjct: 437 I-MIDPPKKAATKLTQEFVRIRKRDHLKPALLFNLIRKLDPTGQKRIVVFVARKETAHRL 495 Query: 262 AHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYM 321 + G V HGSL++E R+++ K K +V LICT G+DI +++ VI Y Sbjct: 496 RIIMGLLGMSVGELHGSLTQEQRLDSVNKFKNLEVPVLICTDLASRGLDIPKIEVVINYD 555 Query: 322 SPRQVNRLIQRAGRS 336 P+ + R GR+ Sbjct: 556 MPKSYEIYLHRVGRT 570 >pir||C69813 RNA helicase homolog yfmL - Bacillus subtilis >gi|2443255|dbj|BAA22326.1| (D86417) YfmL [Bacillus subtilis] >gi|2633067|emb|CAB12572.1| (Z99108) similar to RNA helicase [Bacillus subtilis] Length = 376 Score = 80.4 bits (195), Expect = 8e-14 Identities = 79/332 (23%), Positives = 152/332 (44%), Gaps = 32/332 (9%) Query: 13 FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLK 72 F++ +Q +A + I +GK V+ +PTG+GKT A LPV+ I + P + +AP + Sbjct: 24 FQKPTPVQEQAAQLIMDGKDVIAESPTGTGKTLAYALPVLERIKPEQKHP-QAVILAPSR 82 Query: 73 ALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKSL 132 L + + ++ W+A + +R G ++ ++++ PH+++ TP + L+ K L Sbjct: 83 ELVMQIFQVIQDWKAGSELRAASLIGGANVKKQVEKLKKHPHIIVGTPGRVFELIKAKKL 142 Query: 133 RPYLKNVRFVVVDEVTELI--DNKRGAQLILNLKRLSLIADFIRIGLSATVGNEEE--VK 188 + + V+ +V+DE +L+ +++ + I+ + + D + SAT+ E E ++ Sbjct: 143 K--MHEVKTIVLDETDQLVLPEHRETMKQIIK----TTLRDRQLLCFSATLKKETEDVLR 196 Query: 189 EWLGVDEIVKPPLKK----RYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEK 244 E E++K K + K + L R + K L +L R++ Sbjct: 197 ELAQEPEVLKVQRSKAEAGKVKHQYLICDQRDKVKLLQKLSRLE---------------- 240 Query: 245 HKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSS 304 + LVFV V A +L + V H K R + ++G+ L+ T Sbjct: 241 GMQALVFVRDIGNLSVYAEKLAYHHVELGVLHSEAKKMERAKIIATFEDGEFPLLLATDI 300 Query: 305 MELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 G+DI + VI P + + + R+GR+ Sbjct: 301 AARGLDIENLPYVIHADIPDE-DGYVHRSGRT 331 >pir||B75191 probable ATP-dependent RNA helicase PAB2313 - Pyrococcus abyssi (strain Orsay) >gi|5457486|emb|CAB48977.1| (AJ248283) ATP-dependent RNA helicase, putative [Pyrococcus abyssi] Length = 855 Score = 80.4 bits (195), Expect = 8e-14 Identities = 89/348 (25%), Positives = 156/348 (44%), Gaps = 46/348 (13%) Query: 11 EKFRELNRLQIEAFKR-ISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIA 69 E +EL +Q+ A K + EG+++L+++ T SGKT L + L L++ Sbjct: 212 EGIKELLPVQVLAIKSGLLEGENLLVVSATASGKTLIGELAGIPKALNGK----KMLFLV 267 Query: 70 PLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQV----RNPPHVLITTPETLPA 125 PL AL E + +K G+++ +R G + R + V +++ T E + Sbjct: 268 PLVALANQKYEDFRRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGIDY 327 Query: 126 LLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQL---ILNLKRLSLIADFIRIGLSATVG 182 LL + NV +V+DE+ L D +RG +L I L++L A FI GLSAT+G Sbjct: 328 LLRAGKK---IGNVGTIVIDEIHMLDDEERGPRLDGLIARLRKLYPGAQFI--GLSATIG 382 Query: 183 NEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIV 242 N EE+ + LG+ K++ RP D E ++ + RL V Sbjct: 383 NPEELAKALGM--------------KLVLYDERPVDLERHLVIARNESEKWRLIAKLCKV 428 Query: 243 EKHKR--------VLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEG 294 E +R +VF +R+ LA L G + +H L + R E + + Sbjct: 429 EAMRRSSKGFKGQTIVFTYSRRRCHELASFLTGKGLKAKPYHSGLPYKQRKITEMEFQAQ 488 Query: 295 KVKALICTSSMELGIDIGEVDAVIQ-------YMSPRQVNRLIQRAGR 335 + ++ T+++ G+D + + ++S R+ ++++ RAGR Sbjct: 489 MIDVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLGRAGR 536 >gb|AAK42222.1| ATP-dependent RNA helicase [Sulfolobus solfataricus] Length = 360 Score = 80.0 bits (194), Expect = 1e-13 Identities = 87/338 (25%), Positives = 151/338 (43%), Gaps = 39/338 (11%) Query: 5 LKKAIKEK-FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 L+KA+ E + + R+Q + GKSV++ A TGSGKT A ++P++ Sbjct: 26 LRKALNEAGYIKPTRVQEVVIPELMNGKSVIVQAKTGSGKTAAYVIPILER-------NS 78 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 + L ++P + L +L+ +K I + + G + Y +Q + +++ TP L Sbjct: 79 TALILSPTRELATQILDEIKKLGKYKQIDVSLIIGGMS-YDDQRQSK----IVVGTPGRL 133 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNK--RGAQLILNLKRLSLIADFIRIGLSATV 181 L + + FV+VDE ++D ++ILN + F SAT+ Sbjct: 134 LDLWSKGKID--FSGYDFVIVDEADRMLDMGFIDDIRMILNHCNAKIAGFF-----SATI 186 Query: 182 GNEEEVKEWLGVDEIVKPPLKKRYKF---KVLFPRPRPEDKELAELLRVDVEVAARLRTL 238 DEI+ L K + +++ +P ++ + ++V + ++ L Sbjct: 187 P-----------DEIMT--LAKEFSKDLREIVLDEYKPVEEVKQKFVKVRNDWNDKVSKL 233 Query: 239 WEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKA 298 E + K +LVF TR A L + LK G V + G + + R++ K+GK Sbjct: 234 LEEINGEK-ILVFARTRDRARKLYYLLKGKGVNVGLLSGDMPQSVRLKNFYGFKKGKYNV 292 Query: 299 LICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 L+ T GIDI +V+ VI + PR V I R GR+ Sbjct: 293 LVATDLASRGIDIIDVNKVINFDIPRDVETYIHRVGRT 330 >sp|P41382|IF4U_TOBAC EUKARYOTIC INITIATION FACTOR 4A-10 (EIF-4A-10) (EIF4A-10) >gi|1362118|pir||S55898 translation initiation factor eIF-4A.10 - common tobacco >gi|475213|emb|CAA55642.1| (X79009) translation initiation factor (eIF-4A) [Nicotiana tabacum] >gi|475216|emb|CAA55641.1| (X79008) translation initiation factor (eIF-4A) [Nicotiana tabacum] Length = 413 Score = 80.0 bits (194), Expect = 1e-13 Identities = 79/338 (23%), Positives = 149/338 (43%), Gaps = 23/338 (6%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q +G V+ A +G+GKT V+ L L Sbjct: 51 LLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGVLQQ-LDYSLVEC 109 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L +AP + L + + + ++ G+++ G T+ + +++ HV++ TP + Sbjct: 110 QALVLAPTRELAQQIEKVMRALGDYLGVKVHACVGGTSVREDQRILQSGVHVVVGTPGRV 169 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 +L +SLRP +++ V+DE E++ Q+ L+ I++G+ + Sbjct: 170 FDMLRRQSLRP--DHIKMFVLDEADEMLSRGFKDQIY---DIFQLLPPKIQVGVFSATMP 224 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA---RLRTLWE 240 E + EI + + K + V + +D L + + V V +L TL + Sbjct: 225 PEAL-------EITRKFMNKPVRILV-----KRDDVTLEGIKQFYVNVDKEEWKLETLCD 272 Query: 241 IVEKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKA 298 + E + ++FVNTR+ + L ++++ V HG + + R R+ + G + Sbjct: 273 LYETLAITQSVIFVNTRRKVDWLTDKMRSRDHTVSATHGDMDQNTRDIIMREFRSGSSRV 332 Query: 299 LICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 LI T + GID+ +V VI Y P Q + R GRS Sbjct: 333 LITTDLLARGIDVQQVSLVINYDLPTQPENYLHRIGRS 370 >sp|Q40467|IF4Y_TOBAC EUKARYOTIC INITIATION FACTOR 4A-14 (EIF-4A-14) (EIF4A-14) >gi|485943|emb|CAA55742.1| (X79141) NeIF-4A14 [Nicotiana tabacum] Length = 413 Score = 80.0 bits (194), Expect = 1e-13 Identities = 79/338 (23%), Positives = 149/338 (43%), Gaps = 23/338 (6%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q +G V+ A +G+GKT V+ L L Sbjct: 51 LLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGVLQQ-LDYSLVEC 109 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L +AP + L + + + ++ G+++ G T+ + +++ HV++ TP + Sbjct: 110 QALVLAPTRELAQQIEKVMRALGDYLGVKVHACVGGTSVREDQRILQSGVHVVVGTPGRV 169 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 +L +SLRP +++ V+DE E++ Q+ L+ I++G+ + Sbjct: 170 FDMLRRQSLRP--DHIKMFVLDEADEMLSRGFKDQIY---DIFQLLPPKIQVGVFSATMP 224 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA---RLRTLWE 240 E + EI + + K + V + +D L + + V V +L TL + Sbjct: 225 PEAL-------EITRKFMSKPVRILV-----KRDDVTLEGIKQFYVNVDKEEWKLETLCD 272 Query: 241 IVEKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKA 298 + E + ++FVNTR+ + L ++++ V HG + + R R+ + G + Sbjct: 273 LYETLAITQSVIFVNTRRKVDWLTDKMRSRDHTVSATHGDMDQNTRDIIMREFRSGSSRV 332 Query: 299 LICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 LI T + GID+ +V VI Y P Q + R GRS Sbjct: 333 LITTDLLARGIDVQQVSLVINYDLPTQPENYLHRIGRS 370 >sp|Q09719|YA47_SCHPO PUTATIVE ATP-DEPENDENT RNA HELICASE C31A2.07C >gi|2130418|pir||S59645 probable atp-dependent rna helicase - fission yeast (Schizosaccharomyces pombe) >gi|914885|emb|CAA90465.1| (Z50113) putative atp-dependent rna helicase [Schizosaccharomyces pombe] Length = 848 Score = 80.0 bits (194), Expect = 1e-13 Identities = 87/361 (24%), Positives = 146/361 (40%), Gaps = 31/361 (8%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ K+ F+ +Q + + EG+ V+ +A TGSGKT A ++P++ LK L Sbjct: 80 LLRAIFKKGFKAPTPIQRKTIPLLLEGRDVVGMARTGSGKTAAFVIPMIEH-LKSTLANS 138 Query: 64 S--CLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPE 121 + L ++P + L ++ +K + T +R G + + + P +++ TP Sbjct: 139 NTRALILSPNRELALQTVKVVKDFSKGTDLRSVAIVGGVSLEEQFSLLSGKPDIVVATPG 198 Query: 122 TLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLS--- 178 L L L ++ +VV DE L + AQL L L + + Sbjct: 199 RFLHLKVEMKLE--LSSIEYVVFDEADRLFEMGFAAQLTEILHALPTSRQTLLFSATLPR 256 Query: 179 -----ATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA 233 A G ++ V L V+ V L+ + R L +++++ ++ Sbjct: 257 TLVDFAKAGLQDPVLVRLDVESKVSADLQSAFFSVKTAEREAALLCILQDIIKLPLKDNV 316 Query: 234 RLRTLWEIVEKHKR------------------VLVFVNTRQFAEVLAHRLKTWGKPVEVH 275 R R + + KR LVFV T+ E ++ L G V Sbjct: 317 RPREIGNVNNPKKRKRALELALKGSESGSPDSTLVFVPTKHHVEYVSELLVQAGYSVSKI 376 Query: 276 HGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGR 335 +GSL +EAR+ + GK L+ T GIDI + VI Y P Q + R GR Sbjct: 377 YGSLDQEARLNEINNFRLGKTNLLVVTDVASRGIDIPLLANVINYDFPPQPKVFVHRVGR 436 Query: 336 S 336 + Sbjct: 437 T 437 >emb|CAA11679.1| (AJ223948) RNA helicase [Homo sapiens] Length = 1257 Score = 79.6 bits (193), Expect = 1e-13 Identities = 89/340 (26%), Positives = 154/340 (45%), Gaps = 51/340 (15%) Query: 13 FRELNRLQIEAFKRISEGKS-VLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPL 71 F N +Q + F + S VL+ APTGSGKT AA L + K P +YIAPL Sbjct: 388 FSHFNPVQTQIFHTLYHTDSNVLLGAPTGSGKTVAAELAIFRVFNK--YPTSKAVYIAPL 445 Query: 72 KALNRDLLERLKWW----EAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALL 127 KAL R ER+ W E K G ++ GD T ++ + +++TTPE + Sbjct: 446 KALVR---ERMDDWKVRIEEKLGKKVIELTGDVTPDMKSIAKAD---LIVTTPEKWDGVS 499 Query: 128 TVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIR-----IGLSATVG 182 R Y++ V +++DE+ L+ +RG L + + R + I+ +GLS + Sbjct: 500 RSWQNRNYVQQVTILIIDEI-HLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALA 558 Query: 183 NEEEVKEWLGVDEI--------VKP-PLK---KRYKFKVLFPRPRPEDKELAELLR---- 226 N ++ +WL + ++ V+P PL+ + + + PR +K + +R Sbjct: 559 NARDLADWLNIKQMGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSP 618 Query: 227 ---VDVEVAARLRT--------LWEIVEKHKRVLVFVNTRQFAEVLA----HRLK-TWGK 270 V + V++R +T + E+ + + ++ R+ ++A LK T Sbjct: 619 AKPVLIFVSSRRQTRLTALELIAFLATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAF 678 Query: 271 PVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGID 310 + +HH L + R E KV+ LI TS++ G++ Sbjct: 679 GIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVN 718 >pir||T39411 RNA helicase - fission yeast (Schizosaccharomyces pombe) >gi|3080535|emb|CAA18663.1| (AL022600) DEAD box helicase [Schizosaccharomyces pombe] Length = 1935 Score = 79.6 bits (193), Expect = 1e-13 Identities = 116/430 (26%), Positives = 193/430 (43%), Gaps = 94/430 (21%) Query: 1 MHILLKKAIKEKFRELNRLQIEAFK-RISEGKSVLIIAPTGSGKTEAAILPVMNSI---- 55 M IL +K ++ LNR+Q + +++LI APTG+GKT+ A+L ++ +I Sbjct: 264 MDILCRKTFLS-YQTLNRIQSLVYPIAYKTNENMLICAPTGAGKTDVALLAMLQTISNYV 322 Query: 56 ----LKDGLPPI-------SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYR 104 L D P+ +YIAP+KAL +++E++ A G++ GD + Sbjct: 323 ESMNLMDESEPLDVHRDDFKIVYIAPMKALAAEVVEKMGKRLAWLGLKTRELTGD---MQ 379 Query: 105 RAKQVRNPPHVLITTPETLPALLTVKSL--RPYLKNVRFVVVDEVTELIDNKRGA---QL 159 K +L+TTPE ++T KS+ + VR V++DEV ++ ++RGA L Sbjct: 380 LTKTEIAETQILVTTPEKWD-VVTRKSVGDTQLAEKVRLVIIDEV-HMLHDERGAVIESL 437 Query: 160 ILNLKRL-SLIADFIRI-GLSATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPE 217 + +RL IRI GLSAT+ N +V ++LGV+ K + F F RP P Sbjct: 438 VARTQRLVETSQQMIRIVGLSATLPNYLDVADFLGVNR-----YKGLFYFSSAF-RPCPI 491 Query: 218 D------KELAELLRVDVEVAARLRTLWEIVEKHKRVLVFVNTRQ-------------FA 258 + K +++ +++ A + L I E H +V++FV++R+ F Sbjct: 492 EQHFIGAKGSPKIVNSNIDEACFDKVLKLIQEGH-QVMIFVHSRKETINSAKKLREQFFH 550 Query: 259 E--------------VLAHRLKTWGKPVE----------VHHGSLSKEARIEAERKLKEG 294 E LA R + K E +H+ + + R ER G Sbjct: 551 EGEADLLDNSQHEKYSLAQRDVSKSKNKELKELFKYSMGIHNAGMLRSDRHLTERLFSMG 610 Query: 295 KVKALICTSSMELGIDIGEVDAVI---QYMSPRQ----------VNRLIQRAGRSKHRLL 341 +K L CT+++ G+++ +I Q P++ V ++ RAGR + Sbjct: 611 ILKILCCTATLAWGVNLPAYAVLIKGTQLYDPQKGSFVDLGVLDVLQIFGRAGRPQFESS 670 Query: 342 EVSEAYIIAT 351 V AYII T Sbjct: 671 AV--AYIITT 678 Score = 77.6 bits (188), Expect = 6e-13 Identities = 89/348 (25%), Positives = 159/348 (45%), Gaps = 50/348 (14%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISE-GKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP 62 +L+ ++F N +Q + F I ++ + APTGSGKT AA L ++ P Sbjct: 1123 VLEGICAKRFSFFNAVQTQFFHTIYHTDTNIFVGAPTGSGKTMAAELATWRAL--HNYPK 1180 Query: 63 ISCLYIAPLKALNRDLLERLKWWEAKT----GIRIDVRHGDTTQYRRAKQVRNPPHVLIT 118 +YIAP+KAL + ER+K W + GI + GDT K V N +++IT Sbjct: 1181 SKVVYIAPMKALVK---ERVKDWGHRLVEPMGISMIELTGDTNP--DVKAVTNA-NIIIT 1234 Query: 119 TPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIR---- 174 TPE + R Y+++V +++DE+ L+ + RG L + + R++ +A Sbjct: 1235 TPEKWDGITRSWKSRKYVQDVSLIILDEI-HLLGSDRGPVLEMIVSRMNYVASQTNKKVR 1293 Query: 175 -IGLSATVGNEEEVKEWLGVDE-------IVKP-PLK---KRYKFKVLFPRPRPEDKELA 222 +GLS V N ++ WL + + V+P PL+ + + PR +K Sbjct: 1294 VLGLSTAVANANDLANWLNIRDGLFNFRHSVRPVPLEIYIDGFPGRAYCPRMMSMNKPAF 1353 Query: 223 ELLR-------VDVEVAARLRTLWEI--------VEKHKRVLVFVNTRQF----AEVLAH 263 + ++ V + V++R +T +E + R ++++ + +EV Sbjct: 1354 QAIKTHSPTQPVLIFVSSRRQTRLTAKDLIAFCGLEDNPRRFLYMDEEELEMIVSEVEDK 1413 Query: 264 RLK-TWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGID 310 LK + +HH L++ R +E KV+ LI TS++ G++ Sbjct: 1414 SLKLALPFGIALHHAGLTENDRKISEELFVNNKVQILIATSTLAWGVN 1461 >sp|Q58083|Y669_METJA PUTATIVE ATP-DEPENDENT RNA HELICASE MJ0669 >gi|2127878|pir||E64383 translation initiation factor eIF-4A homolog - Methanococcus jannaschii >gi|1591383|gb|AAB98663.1| (U67514) ATP-dependent RNA helicase, DEAD-family (deaD) [Methanococcus jannaschii] Length = 367 Score = 79.2 bits (192), Expect = 2e-13 Identities = 82/357 (22%), Positives = 162/357 (44%), Gaps = 40/357 (11%) Query: 27 ISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLKALNRDLLERLKWWE 86 +++ +++ A TGSGKT + +P++ + ++ I + + P + L + + ++ + Sbjct: 41 LNDEYNIVAQARTGSGKTASFAIPLIELVNENN--GIEAIILTPTRELAIQVADEIESLK 98 Query: 87 AKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKSLRPYLKNVRFVVVDE 146 ++I +G Y + K ++N ++++ TP + + +L LKNV++ ++DE Sbjct: 99 GNKNLKIAKIYGGKAIYPQIKALKNA-NIVVGTPGRILDHINRGTLN--LKNVKYFILDE 155 Query: 147 VTELIDNK--RGAQLILNL----KRLSLIADFIRIGLSATVGNE--EEVKEWLGVDEIVK 198 E+++ + + ILN KR+ L SAT+ E K+++G +K Sbjct: 156 ADEMLNMGFIKDVEKILNACNKDKRILLF--------SATMPREILNLAKKYMGDYSFIK 207 Query: 199 PPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEKHKRVLVFVNTRQFA 258 + + + + L LL+ K LVF T++ Sbjct: 208 AKINANIEQSYVEVNENERFEALCRLLK----------------NKEFYGLVFCKTKRDT 251 Query: 259 EVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVI 318 + LA L+ G HG LS+ R + R K+ K++ LI T M GID+ +++ VI Sbjct: 252 KELASMLRDIGFKAGAIHGDLSQSQREKVIRLFKQKKIRILIATDVMSRGIDVNDLNCVI 311 Query: 319 QYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIK 375 Y P+ + R GR+ R + +A I E + L +RA++ K++++K Sbjct: 312 NYHLPQNPESYMHRIGRT-GRAGKKGKAISIINRRE--YKKLRYIERAMKLKIKKLK 365 >pir||S52023 translation initiation factor eIF-4A.14 - common tobacco Length = 413 Score = 79.2 bits (192), Expect = 2e-13 Identities = 79/336 (23%), Positives = 150/336 (44%), Gaps = 19/336 (5%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q +G V+ A +G+GKT V+ L L Sbjct: 51 LLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGVLQQ-LDYSLVEC 109 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L +AP + L + + + ++ G+++ G T+ + +++ HV++ TP + Sbjct: 110 QALVLAPTRELAQQIEKVMRALGDYLGVKVHACVGGTSVREDQRILQSGVHVVVGTPGRV 169 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 +L +SLRP +++ V+DE E++ Q+ L+ I++G+ + Sbjct: 170 FDMLRRQSLRP--DHIKMFVLDEADEMLSRGFKDQIY---DIFQLLPPKIQVGVFSATMP 224 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAEL-LRVDVEVAARLRTLWEIV 242 E + EI + + K ++L R + + + + VD E +L TL ++ Sbjct: 225 PEAL-------EITRKFMSK--PVRILVKRDEVTLEGIKQFYVNVDKE-EWKLETLCDLY 274 Query: 243 EKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALI 300 E + ++FVNTR+ + L ++++ V HG + + R R+ + G + LI Sbjct: 275 ETLAITQSVIFVNTRRKVDWLTDKMRSRDHTVSATHGDMDQNTRDIIMREFRSGSSRVLI 334 Query: 301 CTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 T + GID+ +V VI Y P Q + R GRS Sbjct: 335 TTDLLARGIDVQQVSLVINYDLPTQPENYLHRIGRS 370 >pir||T22942 hypothetical protein F58G11.2 - Caenorhabditis elegans >gi|3877945|emb|CAB03153.1| (Z81094) Similarity to Xenopus ATP-dependent RNA helicase (SW:AN3_XENLA), contains similarity to Pfam domain: PF00270 (DEAD/DEAH box helicase), Score=162.7, E-value=5.2e-51, N=1; PF00271 (Helicases conserved C-terminal domain), Score=85.1, E-value=4.7e> Length = 995 Score = 79.2 bits (192), Expect = 2e-13 Identities = 93/372 (25%), Positives = 163/372 (43%), Gaps = 53/372 (14%) Query: 1 MHILLKKAIKE-KFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILK-- 57 +H + + +K K+ + +Q ++ +G VL A T +GKT A LP+++ IL+ Sbjct: 388 LHPTILETLKRIKYNNVRTIQGAMIPQVLDGHDVLGQAETSAGKTAAFGLPIIDKILRMD 447 Query: 58 ----------DGLPPISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAK 107 DG P++ L +AP + L + E L+ + T I + + +G + + R Sbjct: 448 EETRNKARQDDG--PLA-LILAPTRELAAQIHEALRTYCQNTDIIVLLSYGQSDRARSLN 504 Query: 108 QVRNPPHVLITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQL------IL 161 ++RN +LI T + TVKS L ++RF+V DE L+ + + L I Sbjct: 505 EIRNGCDILIGTCGRIMDF-TVKS-HISLLHLRFLVFDEADRLLQDMKKDPLGHLGAIIK 562 Query: 162 NLKRLSLIADFIRIGLSATVGNE------EEVKEWLGVDEIVK-----PPLKKRYKFKVL 210 + + A I SAT E +K G DE++K L KR + Sbjct: 563 DAGFMESAATRQTIMTSATFNASVMTVANELMKRLPGQDEMIKIVLANGRLSKRVNLEFF 622 Query: 211 FPRPRPE-DKELAELLRVDVEVAARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWG 269 + E + +L E+L+ +V K + ++FV + + A +L + G Sbjct: 623 ECKGLAEKNAKLREILKQNVN------------GKTLKTIIFVQKKDQCDACAAKLTSGG 670 Query: 270 KPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSP-----R 324 + HG S++ R + K +V L+ T + GID+ ++D VI + P + Sbjct: 671 MLAQTLHGDRSQDMREKLINDFKSNRVNLLVTTDLLSRGIDVSDLDRVINFDLPDGDPDQ 730 Query: 325 QVNRLIQRAGRS 336 + I RAGR+ Sbjct: 731 GADTFIHRAGRT 742 >gb|AAD20136.1| (AF091502) autoaggregation-mediating protein [Lactobacillus reuteri] Length = 497 Score = 79.2 bits (192), Expect = 2e-13 Identities = 85/340 (25%), Positives = 146/340 (42%), Gaps = 29/340 (8%) Query: 5 LKKAIKEK-FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 L KAIK + E +Q + + EGK V+ A TG+GKT A LP++ ++ + P I Sbjct: 12 LLKAIKRSGYEEATPIQEQTIPMVLEGKDVIGQAQTGTGKTAAFGLPIIENVDTEN-PNI 70 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 + I+P + L E L +R+ V +G R+ K ++ P +L+ TP L Sbjct: 71 QAIIISPTRELAIQTQEELYRLGKDKHVRVQVVYGGADIRRQIKSLKQHPQILVGTPGRL 130 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 + +++ L +++ +V+DE E+ LN+ L I I+ Sbjct: 131 RDHINRHTVK--LDHIKTLVLDEADEM----------LNMGFLEDIESIIK--------E 170 Query: 184 EEEVKEWLGVDEIVKPPLKK-RYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEI- 241 + ++ L + P +K+ +F R + KEL L V AR ++I Sbjct: 171 TPDDRQTLLFSATMPPEIKRIGVQFMSDPETVRIKAKELTTDLVDQYYVRARDYEKFDIM 230 Query: 242 -----VEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKV 296 V+ +VF T++ + L+ L G HG L+++ R + K K ++ Sbjct: 231 TRLIDVQDPDLTIVFGRTKRRVDELSKGLIARGYNAAGIHGDLTQDKRSKIMWKFKNNEL 290 Query: 297 KALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 L+ T G+DI V V Y P + + R GR+ Sbjct: 291 DILVATDVAARGLDISGVTHVYNYDIPSDPDSYVHRIGRT 330 >sp|P41379|IF42_NICPL EUKARYOTIC INITIATION FACTOR 4A-2 (EIF-4A-2) (EIF4A-2) >gi|100275|pir||S22578 translation initiation factor eIF-4A - curled-leaved tobacco >gi|19697|emb|CAA43513.1| (X61205) nicotiana eukaryotic translation initiation factor 4A [Nicotiana plumbaginifolia] Length = 413 Score = 78.8 bits (191), Expect = 2e-13 Identities = 79/336 (23%), Positives = 150/336 (44%), Gaps = 19/336 (5%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q +G V+ A +G+GKT V+ L L Sbjct: 51 LLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGVLQQ-LDYSLVEC 109 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L +AP + L + + + ++ G+++ G T+ + +++ HV++ TP + Sbjct: 110 QALVLAPTRELAQQIEKVMRALGDYLGVKVHACVGGTSVREDQRILQSGVHVVVGTPGRV 169 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 +L +SLRP +++ V+DE E++ Q+ L+ I++G+ + Sbjct: 170 FDMLRRQSLRP--DHIKMFVLDEADEMLSRGFKDQIY---DIFQLLPPKIQVGVFSATMP 224 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAEL-LRVDVEVAARLRTLWEIV 242 E + EI + + K ++L R + + + + VD E +L TL ++ Sbjct: 225 PEAL-------EITRKFMNK--PVRILVKRDELTLEGIKQFYVNVDKE-EWKLETLCDLY 274 Query: 243 EKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALI 300 E + ++FVNTR+ + L ++++ V HG + + R R+ + G + LI Sbjct: 275 ETLAITQSVIFVNTRRKVDWLTDKMRSRDHTVSATHGDMDQNTRDIIMREFRSGSSRVLI 334 Query: 301 CTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 T + GID+ +V VI Y P Q + R GRS Sbjct: 335 TTDLLARGIDVQQVSLVINYDLPTQPENYLHRIGRS 370 >gi|11497691 ATP-dependent RNA helicase, putative [Archaeoglobus fulgidus] >gi|7446071|pir||G69258 ATP-dependent RNA helicase homolog - Archaeoglobus fulgidus >gi|2650581|gb|AAB91160.1| (AE001102) ATP-dependent RNA helicase, putative [Archaeoglobus fulgidus] Length = 759 Score = 78.8 bits (191), Expect = 2e-13 Identities = 102/343 (29%), Positives = 161/343 (46%), Gaps = 53/343 (15%) Query: 20 QIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLKALNRDLL 79 Q EA + EGKS++I APTG+GKTEA+++P + L D LPP +Y P + L + Sbjct: 18 QKEAMDNLLEGKSLIIRAPTGAGKTEASLIPFIYG-LNDYLPP-QLIYSLPTRTLVESIG 75 Query: 80 ERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITT-PETLPALLTVKSLRPYLKN 138 ER + + +R+ + HG ++A +++TT +T A L+V P Sbjct: 76 ERAIKYASFKKLRVAIHHG-----KKATSSLFEEDIIVTTIDQTAGAYLSVPLSMPKRWG 130 Query: 139 VRFV--------VVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGNE--EEVK 188 FV V DEV +D ++G Q + S I +SAT+ + E VK Sbjct: 131 NIFVGGIASALTVFDEV-HTLDPEKGLQTAAAIAMQSAKLGLPSIIMSATLPDVFIERVK 189 Query: 189 EWL----GVDEIV----KPPLKKRYKFKV-LFPRPRPEDKELAELLRVDVEVAARLRTLW 239 E + G EI+ + +K R KV L RP E+L D T+ Sbjct: 190 ERIEKNGGKVEIMDVKNESEIKSRRNRKVELINRP-------DEMLTAD--------TVL 234 Query: 240 EIVEKHKRVLVFVNTRQFAEVLAHRL-KTWGKPVEVHHGSLSKEARIEAERKL-----KE 293 + E ++++V VNT + A+ L L K P+ + H ++ R E E+ K Sbjct: 235 KEAENCRKLVVVVNTVERAQNLYLDLRKKIDYPIFLLHSRYLEKDRAEKEKSFEKVFGKN 294 Query: 294 GKVKAL-ICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGR 335 GK + + I T +E+G+DI ++ ++P ++ LIQRAGR Sbjct: 295 GKGECIFISTQVIEVGMDISS-PIILSEVAP--IDALIQRAGR 334 >pir||A71223 hypothetical protein PH0044 - Pyrococcus horikoshii >gi|3256429|dbj|BAA29112.1| (AP000001) 855aa long hypothetical protein [Pyrococcus horikoshii] Length = 855 Score = 78.4 bits (190), Expect = 3e-13 Identities = 89/367 (24%), Positives = 165/367 (44%), Gaps = 44/367 (11%) Query: 11 EKFRELNRLQIEAFKR-ISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIA 69 E EL +Q+ A K + +G+++L+++ T SGKT L + L+ L++ Sbjct: 212 EGITELLPVQVLAIKNGLLKGENLLVVSATASGKTLIGELAGIPKALEGK----KMLFLV 267 Query: 70 PLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQV----RNPPHVLITTPETLPA 125 PL AL E K +K G+++ +R G + R + V +++ T E + Sbjct: 268 PLVALANQKYEDFKRRYSKLGLKVAIRVGMSRIKTREEPVVVDTGIDADIIVGTYEGVDY 327 Query: 126 LLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQL---ILNLKRLSLIADFIRIGLSATVG 182 LL + NV VV+DE+ + D +RG +L I L++L A FI GLSATVG Sbjct: 328 LLRSGKK---IGNVGTVVIDEIHMIDDEERGPRLDGLIARLRKLYPKAQFI--GLSATVG 382 Query: 183 NEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPED-KELAELLRVDVEVAARLRTLWEI 241 N +E+ LG+ ++ + ++ R E + +A+L + E+ Sbjct: 383 NPQELARSLGMKLVLYDERPVDLERHLIIARNESEKWRIIAKLCKA------------EV 430 Query: 242 VEKHKR-----VLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKV 296 + K + +VF +R+ LA L G + +H L + R E + + + Sbjct: 431 MRKSSKGFKGQTIVFTYSRKRCHELASFLTGKGLKAKPYHSGLPYKQRKITEMEFQAQMI 490 Query: 297 KALICTSSMELGIDIGEVDAVIQ-------YMSPRQVNRLIQRAGRSKHRLLEVSEAYII 349 ++ T+++ G+D + + ++S R+ ++++ RAGR + E + Y+I Sbjct: 491 DVVVTTAALGAGVDFPASQVIFESLAMGNKWLSVREFHQMLGRAGRPLYH--EKGKVYLI 548 Query: 350 ATGVEDY 356 + Y Sbjct: 549 VEPGKKY 555 >gb|AAG20465.1| (AE005119) DNA repair protein; Rad24b [Halobacterium sp. NRC-1] Length = 783 Score = 78.4 bits (190), Expect = 3e-13 Identities = 98/403 (24%), Positives = 162/403 (39%), Gaps = 60/403 (14%) Query: 11 EKFRELNRLQIEAFKR-ISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI-----S 64 E EL Q EA +R ++EG +++ PT SGKT A L ++++I + G P + Sbjct: 20 EGVEELYPPQAEAVERGVTEGANLVASVPTASGKTLIAQLAMLSAIAEGGDSPTFSGDGT 79 Query: 65 CLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLP 124 LYI PL+AL + + + +E + G+ + V G+ Y R +++ T E + Sbjct: 80 ALYIVPLRALAGEKAQEFEAFE-RFGLSVGVSTGN---YERDGARLADNDIVVATSEKVD 135 Query: 125 ALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRL-SLIADFIRIGLSATVGN 183 +L V++ ++ ++ VV DEV + D+ RG L + L +L +AD + LSATVGN Sbjct: 136 SL--VRNGAGWIDDLSCVVADEVHLVDDDHRGPTLEVTLAKLRQQVADLQVVALSATVGN 193 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVE 243 E+ WL + + + V + + D L V + + + + Sbjct: 194 AGELAAWLDAELVDSDWRPIELRTGVHYGQSLHYDDGTQAELSVG-SGSQTAAVVADTLA 252 Query: 244 KHKRVLVFVNTRQFAEVLAHRL------------------------------------KT 267 LVFVN+R+ AE A RL Sbjct: 253 DDGSTLVFVNSRRNAEASARRLADVTGNALSSAERERLADIAAEIRGVSDTETSDELADA 312 Query: 268 WGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGI----------DIGEVDAV 317 HH L++E R E ++ VKA+ T ++ G+ D D Sbjct: 313 VASGAAFHHAGLAREHRELVEEAFRDRLVKAVSATPTLAAGVNTPARRVVVRDWQRYDGT 372 Query: 318 IQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSL 360 M P V + Q GR+ L+ ++ D L+ L Sbjct: 373 AGGMQPLDVLEVHQMFGRAGRPGLDPYGEAVLLANSHDELEEL 415 >pir||S52020 translation initiation factor eIF-4A.15 - common tobacco Length = 413 Score = 78.0 bits (189), Expect = 4e-13 Identities = 78/336 (23%), Positives = 150/336 (44%), Gaps = 19/336 (5%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q +G V+ A +G+GKT V+ + + L Sbjct: 51 LLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGVLQQLAYE-LLEC 109 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L +AP + L + + + ++ G+++ G T+ + + + HV++ TP + Sbjct: 110 QALVLAPTRELAQQIEKVMRALGDYLGVKVTACVGGTSVREDQRILSSGVHVVVGTPGRV 169 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 +L +SLRP +++ V+DE E++ Q+ L+ I++G+ + Sbjct: 170 FDMLRRQSLRP--DHIKMFVLDEADEMLSRGFKDQIY---DIFQLLPPKIQVGVFSATMP 224 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAEL-LRVDVEVAARLRTLWEIV 242 E + EI + + K ++L R + + + + VD E +L TL ++ Sbjct: 225 PEAL-------EITRKFMNK--PVRILVKRDELTLEGIKQFYVNVDKE-EWKLETLCDLY 274 Query: 243 EKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALI 300 E + ++FVNTR+ + L ++++ V HG + + R R+ + G + LI Sbjct: 275 ETLAITQSVIFVNTRRKVDWLTDKMRSRDHTVSATHGDMDQNTRDIIMREFRSGSSRVLI 334 Query: 301 CTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 T + GID+ +V VI Y P Q + R GRS Sbjct: 335 TTDLLARGIDVQQVSLVINYDLPTQPENYLHRIGRS 370 >pir||C69187 conserved hypothetical protein MTH656 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621738|gb|AAB85161.1| (AE000845) ATP-dependent RNA helicase related protein [Methanobacterium thermoautotrophicum] Length = 837 Score = 78.0 bits (189), Expect = 4e-13 Identities = 87/361 (24%), Positives = 156/361 (43%), Gaps = 44/361 (12%) Query: 6 KKAIKEKFRELNRLQIEAFKR----------ISEGKSVLIIAPTGSGKTEAAILPVMNSI 55 K A+ EKF+ + + + R + EG+ +++++ T SGKT A L + Sbjct: 204 KLAVPEKFKRMLKREGNTVLRPVQVLAVDAGLLEGEDLMVVSATASGKTLIAEL----AG 259 Query: 56 LKDGLPPISCLYIAPLKALN----RDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRN 111 + L +Y+ PL AL RD R + KT I++ + ++ R ++R Sbjct: 260 IPRALGGEKFIYLTPLVALANQKYRDFRRRYSPLKLKTAIKVGM-----SRIRARDELRI 314 Query: 112 PP------HVLITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKR 165 P +++ T E + +L L +V VV+DE+ L D +RG++L +KR Sbjct: 315 PETDVSKADIVVGTYEGMDYILRA-GRSGILGDVGVVVIDEIHTLEDEERGSRLKGMIKR 373 Query: 166 LS-LIADFIRIGLSATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAEL 224 + L D I LSATV N EV G+ + + ++F R + K L Sbjct: 374 IRRLFPDAQIIALSATVKNNLEVASEFGLRLVEYDRRPVPLERHLVFSRGEEDKKNLI-- 431 Query: 225 LRVDVEVAARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEAR 284 + +A R + + +VF N+R+ ++A L G +H LS R Sbjct: 432 ----LRLAEREFSTESEKGFRGQTIVFTNSRRKTRLIADYLTRRGVRAAAYHAGLSYRER 487 Query: 285 IEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQ-------YMSPRQVNRLIQRAGRSK 337 ER ++ A++ T+++ G+D V + ++ P + +++ RAGR Sbjct: 488 QRIERAFASQELAAIVTTAALAAGVDFPASQVVFETLLMGNRWLMPNEFAQMLGRAGRPS 547 Query: 338 H 338 + Sbjct: 548 Y 548 >pir||S52018 translation initiation factor eIF-4A.11 - common tobacco Length = 413 Score = 77.6 bits (188), Expect = 6e-13 Identities = 79/336 (23%), Positives = 148/336 (43%), Gaps = 19/336 (5%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q +G V+ A +G+GKT V+ L L Sbjct: 51 LLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGVLQQ-LDYSLVEC 109 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L +AP + L + + + ++ G+++ G T+ + +++ HV++ TP + Sbjct: 110 QALVLAPTRELAQQIEKVMRALGDYLGVKVHACVGGTSVREDQRILQSGVHVVVGTPGRV 169 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 +L +SLRP N++ V+DE E++ Q+ L+ I++G+ + Sbjct: 170 FDMLRRQSLRP--DNIKMFVLDEADEMLSRGFKDQIY---DIFQLLPPKIQVGVFSATMP 224 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAEL-LRVDVEVAARLRTLWEIV 242 E + EI + + K ++L R + + + + VD E +L TL ++ Sbjct: 225 PEAL-------EITRKFMNK--PVRILVKRDELTLEGIKQFYVNVDKE-EWKLETLCDLY 274 Query: 243 EKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALI 300 E + ++FVNTR+ + L +++ V HG + + R R+ + G + LI Sbjct: 275 ETLAITQSVIFVNTRRKVDWLTDKMRGRDHTVSATHGDMDQNTRDIIMREFRSGSSRVLI 334 Query: 301 CTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 T + GID+ +V VI Y P Q + R G S Sbjct: 335 TTDLLARGIDVQQVSLVINYDLPTQPENYLHRIGHS 370 >gb|AAG12945.1|AC073944_8 (AC073944) ethylene-responsive RNA helicase, putative [Arabidopsis thaliana] Length = 501 Score = 77.6 bits (188), Expect = 6e-13 Identities = 80/344 (23%), Positives = 150/344 (43%), Gaps = 29/344 (8%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVM-----NSILKD 58 +L++ K F E +Q + + +G+ ++ IA TGSGKT + +LP + +L Sbjct: 110 VLEEVKKAGFTEPTPIQSQGWPMAMKGRDLIGIAETGSGKTLSYLLPAIVHVNAQPMLAH 169 Query: 59 GLPPISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLIT 118 G PI L +AP + L + + + + + I+ +G + + + ++ ++I Sbjct: 170 GDGPI-VLVLAPTRELAVQIQQEASKFGSSSKIKTTCIYGGVPKGPQVRDLQKGVEIVIA 228 Query: 119 TPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLS 178 TP L ++ +S L+ V ++V+DE ++D Q+ I IR Sbjct: 229 TPGRLIDMM--ESNNTNLRRVTYLVLDEADRMLDMGFDPQI-------RKIVSHIRPDRQ 279 Query: 179 ATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA----- 233 + KE V+++ K L YK + D + +R V+V + Sbjct: 280 TLYWSATWPKE---VEQLSKKFLYNPYKVII-----GSSDLKANRAIRQIVDVISESQKY 331 Query: 234 -RLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLK 292 +L L E + R+LVF++T++ + + +L+ G P HG S+ R + + Sbjct: 332 NKLVKLLEDIMDGSRILVFLDTKKGCDQITRQLRMDGWPALSIHGDKSQAERDWVLSEFR 391 Query: 293 EGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 GK + T G+D+ +V VI Y P + + R GR+ Sbjct: 392 SGKSPIMTATDVAARGLDVKDVKYVINYDFPGSLEDYVHRIGRT 435 >sp|Q40465|IF4V_TOBAC EUKARYOTIC INITIATION FACTOR 4A-11 (EIF-4A-11) (EIF4A-11) >gi|485987|emb|CAA55737.1| (X79136) NeIF-4A11 [Nicotiana tabacum] Length = 413 Score = 77.3 bits (187), Expect = 7e-13 Identities = 78/336 (23%), Positives = 148/336 (43%), Gaps = 19/336 (5%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q +G V+ A +G+GKT ++ L L Sbjct: 51 LLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGILQQ-LDYSLVEC 109 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L +AP + L + + + ++ G+++ G T+ + +++ HV++ TP + Sbjct: 110 QALVLAPTRELAQQIEKVMRALGDYLGVKVHACVGGTSVREDQRILQSGVHVVVGTPGRV 169 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 +L +SLRP N++ V+DE E++ Q+ L+ I++G+ + Sbjct: 170 FDMLRRQSLRP--DNIKMFVLDEADEMLSRGFKDQIY---DIFQLLPPKIQVGVFSATMP 224 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAEL-LRVDVEVAARLRTLWEIV 242 E + EI + + K ++L R + + + + VD E +L TL ++ Sbjct: 225 PEAL-------EITRKFMNK--PVRILVKRDELTLEGIKQFYVNVDKE-EWKLETLCDLY 274 Query: 243 EKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALI 300 E + ++FVNTR+ + L +++ V HG + + R R+ + G + LI Sbjct: 275 ETLAITQSVIFVNTRRKVDWLTDKMRGRDHTVSATHGDMDQNTRDIIMREFRSGSSRVLI 334 Query: 301 CTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 T + GID+ +V VI Y P Q + R G S Sbjct: 335 TTDLLARGIDVQQVSLVINYDLPTQPENYLHRIGHS 370 >sp|P73421|RECQ_SYNY3 ATP-DEPENDENT DNA HELICASE RECQ >gi|7469265|pir||S77358 ATP-dependent DNA helicase recQ - Synechocystis sp. (strain PCC 6803) >gi|1652540|dbj|BAA17461.1| (D90906) ATP-dependent DNA helicase RecQ [Synechocystis sp.] Length = 478 Score = 77.3 bits (187), Expect = 7e-13 Identities = 89/339 (26%), Positives = 157/339 (46%), Gaps = 31/339 (9%) Query: 31 KSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLKALNRDLLERLKWWEAKTG 90 + L++ PTG GK+ LP ++L +GL L ++PL AL D ++ L+ + Sbjct: 35 RDCLVVLPTGGGKSICFQLP---ALLGEGLT----LVVSPLVALMEDQVQSLR----RQN 83 Query: 91 IRIDVRHGDTTQYRRAKQV-----RNPPHVLITTPETLPALLTVKSLRPYLKNVRFVVVD 145 + H ++ R KQV + +L +PETL + LR ++ +++D Sbjct: 84 LPAACLHSQLSRPER-KQVLYQLGQQQLKLLYLSPETLLSEPVWNLLRQPQVKLQGIMLD 142 Query: 146 EVTELI---DNKRGAQLILNLKRLSLIADFIRIGLSATVGNEEEVKEWLGVDEIVKPPLK 202 E L+ D+ R A L R L D +I L+A + ++ L V+ + L+ Sbjct: 143 EAHCLVQWGDSFRPAYRRLGALRRGLGRDKGQIPLAAFTATADRQQQNLIVEGL---NLR 199 Query: 203 KRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEKHKRV--LVFVNTRQFAEV 260 F+V RP+ K +++ + R + L + KH + L++V TR A Sbjct: 200 SPECFQVSPHRPQLHLK-----VKMVLSEYCRRQQLRRFLLKHLQESGLIYVRTRTMAIN 254 Query: 261 LAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQY 320 LA L+ G E +HG L R + E+K G++ +++CT++ LGID + V+ Y Sbjct: 255 LAQWLQERGFDSEAYHGGLGPHQRRQLEQKWLTGQISSVVCTNAFGLGIDKPDTRWVLHY 314 Query: 321 MSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQS 359 +P + +Q GR+ R L+ +E + + +L S Sbjct: 315 QAPLMLMDYLQEVGRA-GRDLQPAECLTLVSEPTGWLDS 352 >emb|CAC11964.1| (AL445065) DNA helicase related protein [Thermoplasma acidophilum] Length = 674 Score = 77.3 bits (187), Expect = 7e-13 Identities = 88/389 (22%), Positives = 164/389 (41%), Gaps = 80/389 (20%) Query: 23 AFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLKALNRDLLERL 82 A ++I +G++V++ PT +GKT A + + ++ + +YI PL++L + L Sbjct: 30 AIEQIRKGRNVVVSVPTAAGKTLIAYSAIYETFQRN----LKSIYIVPLRSLAMEKFSEL 85 Query: 83 KWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKSLRPYLKN-VRF 141 G+++ + GD Y + +I T E +LL PY+ N V Sbjct: 86 SRLR-DLGLKVKMSIGD---YDDSPDFIKRYDAVILTSEKADSLLHHD---PYILNDVGL 138 Query: 142 VVVDEVTELIDNKRGAQLILNLKRLSLIADFIR-----IGLSATVGNEEEVKEWLGVDEI 196 +V+DE+ + D RG L+ ++ IA ++ + LSATV N E+ WL I Sbjct: 139 LVLDEIHTIGDESRGP----TLETVASIARYVNPDVRILALSATVSNAMELASWLDASLI 194 Query: 197 VKP----PLKKR--YKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEKHKRVLV 250 PLK Y+ ++ R + +++R E VE + +VL+ Sbjct: 195 KSDFRPVPLKTGILYRDQLYLDGKRRSGVSINQIIR-------------ETVEDNGQVLM 241 Query: 251 FVNTRQFAEVLAHRL-------------------------KTWGKPVEVHHGSLSKEARI 285 FV++R+ AE A L + + V HH LS + R Sbjct: 242 FVSSRKKAEDTARDLAQIFGSDANIKISSDETNVYDDMLNEILPRGVAFHHAGLSNDQRA 301 Query: 286 EAERKLKEGKVKALICTSSMELGIDIGEVDAV-----------IQYMSPRQVNRLIQRAG 334 ER+ + ++K ++ T ++ G+++ + I Y++ ++ ++I RAG Sbjct: 302 FIEREFRARRIKVIVATPTLAAGVNLPARLVIVRDITRWGSDGISYLTNMEIKQMIGRAG 361 Query: 335 RSKHRLLEVSEAYIIA----TGVEDYLQS 359 R + + Y+ + +DYL + Sbjct: 362 RPGYDQYGIGLIYVSSQSSYEAAKDYLST 390 >gi|6320041 (putative) DEAD box RNA helicase; Dhh1p [Saccharomyces cerevisiae] >gi|729329|sp|P39517|DHH1_YEAST PUTATIVE ATP-DEPENDENT RNA HELICASE DHH1 >gi|320822|pir||S31229 probable RNA helicase (EC 3.6.1.-) DHH1 - yeast (Saccharomyces cerevisiae) >gi|4353|emb|CAA46853.1| (X66057) RNA-helicase of the DEAD-BOX family [Saccharomyces cerevisiae] >gi|1061279|emb|CAA91586.1| (Z67750) putative RNA helicase [Saccharomyces cerevisiae] >gi|1431254|emb|CAA98734.1| (Z74208) ORF YDL160c [Saccharomyces cerevisiae] Length = 506 Score = 76.9 bits (186), Expect = 9e-13 Identities = 79/338 (23%), Positives = 143/338 (41%), Gaps = 25/338 (7%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL + F + + +Q EA G+ +L A G+GKT A ++P + + K L I Sbjct: 57 LLMGIFEAGFEKPSPIQEEAIPVAITGRDILARAKNGTGKTAAFVIPTLEKV-KPKLNKI 115 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L + P + L + ++ GI V G T ++ H+L+ TP + Sbjct: 116 QALIMVPTRELALQTSQVVRTLGKHCGISCMVTTGGTNLRDDILRLNETVHILVGTPGRV 175 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 L + K L + ++DE +++ R + I+ L + SAT Sbjct: 176 LDLASRKVAD--LSDCSLFIMDEADKMLS--RDFKTIIEQILSFLPPTHQSLLFSATFP- 230 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAAR-----LRTL 238 L V E + L K Y+ ++ E+ L + + V R L TL Sbjct: 231 -------LTVKEFMVKHLHKPYEINLM------EELTLKGITQYYAFVEERQKLHCLNTL 277 Query: 239 WEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKA 298 + ++ ++ + +F N+ E+LA ++ G H + ++ R + + ++GKV+ Sbjct: 278 FSKLQINQAI-IFCNSTNRVELLAKKITDLGYSCYYSHARMKQQERNKVFHEFRQGKVRT 336 Query: 299 LICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 L+C+ + GIDI V+ VI + P+ + R GRS Sbjct: 337 LVCSDLLTRGIDIQAVNVVINFDFPKTAETYLHRIGRS 374 >sp|P41378|IF4A_WHEAT EUKARYOTIC INITIATION FACTOR 4A (EIF-4A) (EIF4A) >gi|478306|pir||JN0839 translation initiation factor eIF-4A - wheat Length = 414 Score = 76.9 bits (186), Expect = 9e-13 Identities = 78/338 (23%), Positives = 147/338 (43%), Gaps = 23/338 (6%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q +G V+ A +G+GKT ++ L GL Sbjct: 52 LLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGILQQ-LDYGLVEC 110 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L +AP + L + + + ++ G+++ G T+ + + + HV++ TP + Sbjct: 111 QALVLAPTRELAQQIEKVMRALGDYLGVKVHACVGGTSVREDQRILASGVHVVVGTPGRV 170 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 ++ +SLRP N++ V+DE E++ Q+ L+ I++G+ + Sbjct: 171 FDIVRRQSLRP--DNIKMFVLDEADEMLSRGFKDQIY---DIFQLLPGKIQVGVFSATMP 225 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA---RLRTLWE 240 E + EI + + K + V + ++ L + + V V +L TL + Sbjct: 226 PEAL-------EITRKFMNKPVRILV-----KRDELTLEGIKQFYVNVEKEEWKLDTLCD 273 Query: 241 IVEKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKA 298 + E + ++FVNTR+ + L +++ V HG + + R R+ + G + Sbjct: 274 LYETLAITQSVIFVNTRRKVDWLTDKMRGRDHTVSATHGDMDQNTRDIIMREFRSGSSRV 333 Query: 299 LICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 LI T + GID+ +V VI Y P Q R GRS Sbjct: 334 LITTDLLARGIDVQQVSLVINYDLPTQPENYQHRIGRS 371 >pir||S52017 translation initiation factor eIF-4A.9 - common tobacco Length = 413 Score = 76.9 bits (186), Expect = 9e-13 Identities = 78/336 (23%), Positives = 150/336 (44%), Gaps = 19/336 (5%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q +G V+ A +G+GKT V+ + + L Sbjct: 51 LLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGVLQQLDYE-LLEC 109 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L +AP + L + + + ++ G+++ G T+ + + + HV++ TP + Sbjct: 110 QALVLAPTRELAQQIEKVMRALGDYLGVKVHACVGGTSVREDQRILSSGVHVVVGTPGRV 169 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 +L +SLRP +++ V+DE E++ Q+ L+ I++G+ + Sbjct: 170 FDMLRRQSLRP--DHIKMFVLDEADEMLSRGFKDQIY---DIFQLLPPKIQVGVFSATMP 224 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAEL-LRVDVEVAARLRTLWEIV 242 E + EI + + K ++L R + + + + VD E +L TL ++ Sbjct: 225 PEAL-------EITRKFMNK--PVRILVKRDELTLEGIKQFYVNVDKE-EWKLETLCDLY 274 Query: 243 EKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALI 300 E + ++FVNTR+ + L ++++ V HG + + R R+ + G + LI Sbjct: 275 ETLAITQSVIFVNTRRKVDWLTDKMRSRDHTVSATHGDMDQNTRDIIMREFRSGSSRVLI 334 Query: 301 CTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 T + GID+ +V VI Y P Q + R GRS Sbjct: 335 TTDLLARGIDVQQVSLVINYDLPTQPENYLHRIGRS 370 >sp|Q40471|IF49_TOBAC EUKARYOTIC INITIATION FACTOR 4A-9 (EIF-4A-9) (EIF4A-9) >gi|485951|emb|CAA55736.1| (X79135) NeIF-4A9 [Nicotiana tabacum] Length = 413 Score = 76.5 bits (185), Expect = 1e-12 Identities = 77/336 (22%), Positives = 150/336 (43%), Gaps = 19/336 (5%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q +G V+ A +G+GKT ++ + + L Sbjct: 51 LLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGILQQLDYE-LLDC 109 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L +AP + L + + + ++ G+++ G T+ + + + HV++ TP + Sbjct: 110 QALVLAPTRELAQQIEKVMRALGDYLGVKVHACVGGTSVREDQRILSSGVHVVVGTPGRV 169 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 +L +SLRP +++ V+DE E++ Q+ L+ I++G+ + Sbjct: 170 FDMLRRQSLRP--DHIKMFVLDEADEMLSRGFKDQIY---DIFQLLPPKIQVGVFSATMP 224 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAEL-LRVDVEVAARLRTLWEIV 242 E + EI + + K ++L R + + + + VD E +L TL ++ Sbjct: 225 PEAL-------EITRKFMNK--PVRILVKRDELTLEGIKQFYVNVDKE-EWKLETLCDLY 274 Query: 243 EKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALI 300 E + ++FVNTR+ + L ++++ V HG + + R R+ + G + LI Sbjct: 275 ETLAITQSVIFVNTRRKVDWLTDKMRSRDHTVSATHGDMDQNTRDIIMREFRSGSSRVLI 334 Query: 301 CTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 T + GID+ +V VI Y P Q + R GRS Sbjct: 335 TTDLLARGIDVQQVSLVINYDLPTQPENYLHRIGRS 370 >pir||S53814 DEAD box protein - slime mold (Dictyostelium discoideum) (fragment) >gi|550329|emb|CAA57417.1| (X81823) putative RNA helicase [Dictyostelium discoideum] Length = 582 Score = 76.5 bits (185), Expect = 1e-12 Identities = 91/370 (24%), Positives = 155/370 (41%), Gaps = 25/370 (6%) Query: 1 MHILLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGL 60 +H+LLKK EK +Q + I G+ ++ IA TGSGKT A +LP+ IL Sbjct: 33 VHLLLKKFQYEK---PTSIQAQTIPAIMNGRDLIGIARTGSGKTLAFLLPMFRHILAQPK 89 Query: 61 PP----ISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVL 116 + L ++P + L + K + G+R +G + + +++ ++ Sbjct: 90 SAPGEGMIALIMSPTRELALQIHVECKKFSKVLGLRTACVYGGASISEQIAELKRGADIV 149 Query: 117 ITTPETLPALLTVKSLR-PYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRI 175 + TP + +L + R L+ V F+V+DE + D G Q +N S+ D I Sbjct: 150 VCTPGRMIDILCANNRRITNLRRVTFLVLDEADRMFDMGFGPQ--INCIVDSIRPDRQTI 207 Query: 176 GLSATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARL 235 SAT + V+ + K L K +++ ++ + + V R Sbjct: 208 MFSATFPPK--------VENVAKKILNK--PLEIIAGGRSIVSSDIEQFVEVR-PTETRF 256 Query: 236 RTLWEIVE--KHK-RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLK 292 R L E++ HK ++L+F N ++ + L +L HGS + R E K Sbjct: 257 RRLIELLSIWYHKGQILIFTNRQETTDNLYRQLSNSQYQCLSLHGSKDQTDRDETISDFK 316 Query: 293 EGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATG 352 LI T G+DI +++ V+ + P + + R GR+ R AY T Sbjct: 317 NKVKTILIATPLASRGLDIKDLNLVVNFDCPDHLEDYVHRVGRT-GRAGNRGTAYTFITP 375 Query: 353 VEDYLQSLII 362 E+ S II Sbjct: 376 DEERFSSSII 385 >sp|O01836|GLH3_CAEEL ATP-DEPENDENT RNA HELICASE GLH-3 (GERMLINE HELICASE-3) >gi|7446042|pir||T15231 germline RNA helicase-3 - Caenorhabditis elegans >gi|2088766|gb|AAB57719.1| (AF003145) Contains similarity to Pfam domain: PF00098 (zf-CCHC), Score=24.0, E-value=0.00099, N=2 [Caenorhabditis elegans] >gi|3386542|gb|AAC28388.1| (AF079509) germline RNA helicase-3 [Caenorhabditis elegans] Length = 720 Score = 76.5 bits (185), Expect = 1e-12 Identities = 80/331 (24%), Positives = 146/331 (43%), Gaps = 29/331 (8%) Query: 27 ISEGKSVLIIAPTGSGKTEAAILPVMNSIL---------KDGLPPISCLYIAPLKALNRD 77 +++GK +L A TGSGKT A +LP+M+ ++ + G P C+ + P + L Sbjct: 332 VADGKDILACAQTGSGKTAAFLLPIMSRLILEKDLNYGAEGGCYP-RCIILTPTRELADQ 390 Query: 78 LLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKSLRPYLK 137 + + + ++ + I +G Q+ +++ T + +++ L Sbjct: 391 IYNEGRKFSYQSVMEIKPVYGGINVGYNKSQIMKGCTIIVGTIGRVKHFCEDGAIK--LD 448 Query: 138 NVRFVVVDEVTELIDNKR-GAQL--ILNLKRLSLIADFIRIGLSATVGNE---------E 185 R++V+DE +ID+ G ++ I+N K + + SAT + Sbjct: 449 KCRYLVLDEADRMIDSMGFGPEIEQIINYKNMPKNDKRQTMMFSATFPSSVQEAARKLLR 508 Query: 186 EVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEKH 245 E + +D+I +F+ L R DK L +LL +D++ + V Sbjct: 509 EDYTMITIDKIGAANKCVIQEFE-LCDRTSKVDK-LLKLLGIDIDTYTTEKNSDVFV--- 563 Query: 246 KRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSM 305 K+ +VFV ++ A+ LA + P HG+ ++ R A + + G LI T+ + Sbjct: 564 KKTIVFVAQQKMADTLASIMSAAQVPAITIHGAREQKERSAALKLFRSGAKPVLIATAVV 623 Query: 306 ELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 E G+DI VD VI Y P ++ I R GR+ Sbjct: 624 ERGLDIKGVDHVINYDMPNNIDDYIHRIGRT 654 >pir||H69124 translation initiation factor eIF-4A homolog - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621248|gb|AAB84709.1| (AE000807) ATP-dependent RNA helicase, eIF-4A family [Methanobacterium thermoautotrophicum] Length = 425 Score = 76.5 bits (185), Expect = 1e-12 Identities = 77/313 (24%), Positives = 142/313 (44%), Gaps = 27/313 (8%) Query: 29 EGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLKALNRDLLERLKWWEAK 88 +G V+ A TG+GKT A +PV+ ++ + +P L I P + L + E +K Sbjct: 40 DGMDVVGEAQTGTGKTAAFAIPVLENLEAERVP--QALIICPTRELCLQVSEEIKRIGKY 97 Query: 89 TGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKSLRPYLKNVRFVVVDEVT 148 +++ +G + + Q+R HV++ TP L + ++ L + VV+DE Sbjct: 98 MKVKVLAVYGGQSIGNQIAQLRRGVHVIVATPGRL--IDHIERGTVDLGGISTVVLDEAD 155 Query: 149 ELIDNKRGAQLILNLKR-LSLIADFIRIGL-SATVGNE--EEVKEWLGVDEIVKPPLKKR 204 E+++ I +++R LS + + + L SATV ++++ ++++ K Sbjct: 156 EMLN----MGFIDDIERILSHVPERRQTMLFSATVSKPILRIARKYMRNPQVMRVEKKHS 211 Query: 205 YKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEKHKRV-LVFVNTRQFAEVLAH 263 K + + R EDK ELL W + + R+ L+F NT++ + L Sbjct: 212 PKIDEFYFKTREEDK--VELLD------------WILSSNNIRMGLIFCNTKRRVQRLRR 257 Query: 264 RLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSP 323 +L G + HG LS+ R + + G L+ T GI + +V+AV+ Y P Sbjct: 258 QLNRMGYSADEIHGDLSQSKRERVMERFRRGDFSLLVATDVAARGIHVPDVEAVVNYDLP 317 Query: 324 RQVNRLIQRAGRS 336 + + R GR+ Sbjct: 318 FENEYYVHRIGRT 330 >gb|AAK42080.1| ATP-dependent RNA helicase [Sulfolobus solfataricus] Length = 343 Score = 76.1 bits (184), Expect = 2e-12 Identities = 85/338 (25%), Positives = 146/338 (43%), Gaps = 39/338 (11%) Query: 5 LKKAIKEK-FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 L+KA+ E + + ++Q + GKSV+ A TGSGKT A ++P++ Sbjct: 9 LRKALSEAGYIKPTKVQEVVIPELLNGKSVIAQAKTGSGKTAAYVIPILER-------NS 61 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 + L ++P + L +L+ ++ I + + G + Y +Q R +++ TP L Sbjct: 62 TALILSPTRELATQILDEIRKLGKYKQIDVSLIIGGMS-YDGQRQSR----IVVGTPGRL 116 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNK--RGAQLILNLKRLSLIADFIRIGLSATV 181 L + + ++VDE ++D ++ILN + F SAT+ Sbjct: 117 LDLWSKGKID--FSGYDVIIVDEADRMLDMGFIDDIRMILNHSNAKITGFF-----SATI 169 Query: 182 GNE--EEVKEWL-GVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTL 238 +E KE+ + EIV K + K +F + R + + L ++ Sbjct: 170 PDEIMTLAKEFSKDLREIVLDEYKPVEEVKQIFVKVRNDWSDKVSKLLEEIS-------- 221 Query: 239 WEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKA 298 +++LVF TR A L L+ G V + G + + R++ K+GK Sbjct: 222 ------GEKILVFARTRDRARKLYFLLRGKGVNVGLLSGDMPQSVRLKNFYGFKKGKYNV 275 Query: 299 LICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 L+ T GIDI +VD VI + PR V I R GR+ Sbjct: 276 LVATDLASRGIDIVDVDKVINFDIPRDVETYIHRVGRT 313 >sp|Q40468|IF4Z_TOBAC EUKARYOTIC INITIATION FACTOR 4A-15 (EIF-4A-15) (EIF4A-15) >gi|485945|emb|CAA55739.1| (X79138) NeIF-4A15 [Nicotiana tabacum] Length = 413 Score = 76.1 bits (184), Expect = 2e-12 Identities = 76/336 (22%), Positives = 150/336 (44%), Gaps = 19/336 (5%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q +G V+ A +G+GKT ++ + + L Sbjct: 51 LLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGILQQLAYE-LLEC 109 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L +AP + L + + + ++ G+++ G T+ + + + HV++ TP + Sbjct: 110 QALVLAPTRELAQQIEKVMRALGDYLGVKVTACVGGTSVREDQRILSSGVHVVVGTPGRV 169 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 +L +SLRP +++ V+DE E++ Q+ L+ I++G+ + Sbjct: 170 FDMLRRQSLRP--DHIKMFVLDEADEMLSRGFKDQIY---DIFQLLPPKIQVGVFSATMP 224 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAEL-LRVDVEVAARLRTLWEIV 242 E + EI + + K ++L R + + + + VD E +L TL ++ Sbjct: 225 PEAL-------EITRKFMNK--PVRILVKRDELTLEGIKQFYVNVDKE-EWKLETLCDLY 274 Query: 243 EKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALI 300 E + ++FVNTR+ + L ++++ V HG + + R R+ + G + LI Sbjct: 275 ETLAITQSVIFVNTRRKVDWLTDKMRSRDHTVSATHGDMDQNTRDIIMREFRSGSSRVLI 334 Query: 301 CTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 T + GID+ +V VI + P Q + R GRS Sbjct: 335 TTDLLARGIDVQQVSLVINFDLPTQPENYLHRIGRS 370 >gb|AAG22819.1|AF302423_1 (AF302423) RNA helicase II/Gu [Xenopus laevis] Length = 759 Score = 74.9 bits (181), Expect = 4e-12 Identities = 72/330 (21%), Positives = 154/330 (45%), Gaps = 24/330 (7%) Query: 19 LQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPIS-----CLYIAPLKA 73 +Q + F GK V++ A TG+GKT + +P++ + +D P + + P + Sbjct: 205 IQSKTFHTAYSGKDVVVQARTGTGKTFSFAIPLVEKLNEDQQPLARGRAPRVIILTPTRE 264 Query: 74 LNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKSLR 133 L + ++ K +++ +G T ++ +++ L+ TP + L V++ R Sbjct: 265 LAIQITNEIRSITKK--LKVSCFYGGTPYQQQVFAIKDGIDFLVGTPGRVRDL--VQNYR 320 Query: 134 PYLKNVRFVVVDEVTELIDNKRGAQL--ILNLKRLSLIADFIRIGL-SATVGNEEEVKEW 190 L ++ VV+DEV + D Q+ IL+++ + + + L SAT +W Sbjct: 321 LDLTTLKHVVLDEVDMMFDMGFSEQVEEILSVRYKADPEENPQTLLFSATC------PDW 374 Query: 191 LGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVE----KHK 246 + + K ++K+++ L + E L ++ + + L ++V+ H Sbjct: 375 MY--NMAKKYMRKQFEKIDLIGHRSQKAATTVEHLAIECTRSQKAAVLGDLVQVYSGSHG 432 Query: 247 RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSME 306 + ++F +++ A LA + + + HG L ++ R + ++G + LI T+ Sbjct: 433 KTIIFCDSKLEAHTLATSCGSLKQSAKSLHGDLQQKEREVVLKGFRQGTFEVLIATNVAA 492 Query: 307 LGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 G+DI EVD V+ Y +P++ + + R+GR+ Sbjct: 493 RGLDIPEVDLVVLYSAPKEADAYVHRSGRT 522 >dbj|BAB06103.1| (AP001515) ATP-dependent RNA helicase [Bacillus halodurans] Length = 539 Score = 74.9 bits (181), Expect = 4e-12 Identities = 85/347 (24%), Positives = 145/347 (41%), Gaps = 44/347 (12%) Query: 5 LKKAIKEK-FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 +KKAI E F E + +Q +A I G V+ A TG+GKT A +PV+ + + Sbjct: 17 IKKAIIEMGFEEPSPIQAKAIPAILAGGDVIGQAQTGTGKTAAFGIPVVEKVSTGR--HV 74 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L + P + L + ++ IR +G + + K ++ V+I TP + Sbjct: 75 QALILTPTRELAIQVSGEIQKLSKHKKIRTLPIYGGQSIVHQIKALKQGVQVVIGTPGRI 134 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 L K+L L +V V++DE E++D + I D I V N Sbjct: 135 IDHLRRKTL--ILDHVNTVILDEADEMLD-------------MGFIDDIESI--LRQVKN 177 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVE 243 E + L + P +KK R D + + R +V + + ++++E Sbjct: 178 ERQT---LLFSATMPPAIKK-------LSRKYMNDPQTVSINRREVTAPSIDQFYYKVLE 227 Query: 244 KHK-----RVL---------VFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAER 289 ++K R++ +F T++ L L+ G + HG L++ R R Sbjct: 228 RNKLDSLCRIIDSEQIDLGILFCRTKKGVAELTEALQARGYIADGLHGDLTQSQRDAVMR 287 Query: 290 KLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 K ++ ++ LI T GID+G V VI Y P+ + R GR+ Sbjct: 288 KFRDSSIEFLIATDVAARGIDVGNVSHVINYDIPQDPESYVHRIGRT 334 >gb|AAF49564.2| (AE003529) CG5931 gene product [Drosophila melanogaster] Length = 2149 Score = 74.5 bits (180), Expect = 5e-12 Identities = 89/398 (22%), Positives = 171/398 (42%), Gaps = 82/398 (20%) Query: 11 EKFRELNRLQIEAFKR-ISEGKSVLIIAPTGSGKTEAAILPVMNSILK----DG---LPP 62 E F+ LNR+Q +K + +++L+ APTG+GKT A+L +M I K DG Sbjct: 495 EGFKTLNRIQSRLYKAALDSDENMLLCAPTGAGKTNVALLTMMREIGKHINEDGTINAQD 554 Query: 63 ISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPET 122 +Y+AP+K+L ++++ A + + GD ++ ++ V++ TPE Sbjct: 555 FKIIYVAPMKSLVQEMVGNFGRRLACYNLTVSELTGD---HQLTREQIAATQVIVCTPEK 611 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRG----AQLILNLKRLSLIADFIR-IGL 177 + R ++ VR V++DE+ L+ ++RG A + ++ + + +R +GL Sbjct: 612 WDIITRKGGERTFVSLVRLVIIDEI-HLLHDERGPVLEALVARTIRNIETTQEEVRLVGL 670 Query: 178 SATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRT 237 SAT+ N ++V +L V P K + F + RP E + + + R + Sbjct: 671 SATLPNYQDVATFLRV-----KPDKGLFYFDNSY---RPVSLEQQYIGVTEKKALKRFQV 722 Query: 238 LWEIVEK-------HKRVLVFVNTRQFA--------------EVLAHRLKTWGKPVEV-- 274 + EIV + +VLVFV++R+ + L LK +EV Sbjct: 723 MNEIVYEKTMEHAGRNQVLVFVHSRKETGKTARAVRDMCLEQDTLGSFLKEGSASMEVLR 782 Query: 275 ---------------------HHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGE 313 HH +++ R E + ++ L+ T+++ G+++ Sbjct: 783 TEAEQVKNTELKELLPYGFAIHHAGMTRVDRTLVEDLFADRHIQVLVSTATLAWGVNLPA 842 Query: 314 VDAVIQ-------------YMSPRQVNRLIQRAGRSKH 338 +I+ +S V +++ RAGR ++ Sbjct: 843 HTVIIKGTQVYNPEKGRWVELSALDVLQMLGRAGRPQY 880 >sp|P41376|IF41_ARATH EUKARYOTIC INITIATION FACTOR 4A-1 (EIF-4A-1) (EIF4A-1) >gi|322503|pir||JC1452 translation initiation factor eIF-4A1 - Arabidopsis thaliana >gi|16554|emb|CAA46188.1| (X65052) eukaryotic translation initiation factor 4A-1 [Arabidopsis thaliana] >gi|9229290|dbj|BAA99593.1| (AB019229) eukaryotic translation initiation factor; RNA helicase [Arabidopsis thaliana] Length = 412 Score = 74.5 bits (180), Expect = 5e-12 Identities = 77/338 (22%), Positives = 147/338 (42%), Gaps = 23/338 (6%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q +G V+ A +G+GKT V+ L L Sbjct: 50 LLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGVLQQ-LDFSLIQC 108 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L +AP + L + + + ++ G+++ G T+ + ++ HV++ TP + Sbjct: 109 QALVLAPTRELAQQIEKVMRALGDYLGVKVHACVGGTSVREDQRILQAGVHVVVGTPGRV 168 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 +L +SLR N++ V+DE E++ Q+ L+ I++G+ + Sbjct: 169 FDMLKRQSLRA--DNIKMFVLDEADEMLSRGFKDQIY---DIFQLLPPKIQVGVFSATMP 223 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA---RLRTLWE 240 E + EI + + K + V + ++ L + + V V +L TL + Sbjct: 224 PEAL-------EITRKFMSKPVRILV-----KRDELTLEGIKQFYVNVEKEEWKLETLCD 271 Query: 241 IVEKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKA 298 + E + ++FVNTR+ + L ++++ V HG + + R R+ + G + Sbjct: 272 LYETLAITQSVIFVNTRRKVDWLTDKMRSRDHTVSATHGDMDQNTRDIIMREFRSGSSRV 331 Query: 299 LICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 LI T + GID+ +V VI + P Q + R GRS Sbjct: 332 LITTDLLARGIDVQQVSLVINFDLPTQPENYLHRIGRS 369 >sp|P54475|YQFR_BACSU PROBABLE RNA HELICASE IN CCCA-SODA INTERGENIC REGION >gi|7446094|pir||D69954 ATP-dependent RNA helicase homolog yqfR - Bacillus subtilis >gi|1303839|dbj|BAA12495.1| (D84432) YqfR [Bacillus subtilis] >gi|2634947|emb|CAB14444.1| (Z99116) similar to ATP-dependent RNA helicase [Bacillus subtilis] Length = 438 Score = 74.5 bits (180), Expect = 5e-12 Identities = 81/331 (24%), Positives = 148/331 (44%), Gaps = 25/331 (7%) Query: 13 FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLK 72 F E +Q + + +SV+ + TG+GKT A +LP++N I + + AP + Sbjct: 24 FYEPTDIQKRLIPAVLKKESVIGQSQTGTGKTHAYLLPLLNKI-DPAKDVVQVVITAPTR 82 Query: 73 AL-NRDLLERLKWWEAKTG--IRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTV 129 L N+ E LK + + G IR G T + + +++ PH+++ TP + L+ Sbjct: 83 ELANQIYQEALKITQGEEGSQIRSKCFIGGTDKQKSIDKLKIQPHLVVGTPGRIADLIKE 142 Query: 130 KSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGNEEEVKE 189 ++L + +V+DE ++D + +AD IG S + + + Sbjct: 143 QALSVH--KAESLVIDEADLMLD-------------MGFLADVDYIG-SRMPEDLQMLVF 186 Query: 190 WLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRT--LWEIVEKHKR 247 + E +KP LKK Y + P+ A++ + + R + L++I+ Sbjct: 187 SATIPEKLKPFLKK-YMENPKYAHVEPKQVTAAKIEHILIPSKHRDKDKLLFDIMSHLNP 245 Query: 248 VL--VFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSM 305 L VF NT+ A+ +A L G + + HG L+ R + +++ + + +I T Sbjct: 246 YLGIVFANTKNTADHIAQYLTGKGMKIGLLHGGLTPRERKKVMKQINDLEFTYIIATDLA 305 Query: 306 ELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 GIDI V VI Y P ++ + R GR+ Sbjct: 306 ARGIDIKGVSHVINYELPDDLDFYVHRVGRT 336 >gi|11499835 ATP-dependent RNA helicase, DEAD-family (deaD) [Archaeoglobus fulgidus] >gi|7446036|pir||F69531 ATP-dependent RNA helicase, DEAD-family (deaD) homolog - Archaeoglobus fulgidus >gi|2648271|gb|AAB89003.1| (AE000949) ATP-dependent RNA helicase, DEAD-family (deaD) [Archaeoglobus fulgidus] Length = 368 Score = 74.5 bits (180), Expect = 5e-12 Identities = 79/336 (23%), Positives = 149/336 (43%), Gaps = 28/336 (8%) Query: 8 AIKEK-FRELNRLQIEAFKRISEGKSVLI-IAPTGSGKTEAAILPVMNSILKDGLPPISC 65 A++ K F + +Q E R EG+ ++ A TGSGKT A LP+++ ++ + + Sbjct: 21 AVRRKGFEKPTEIQREIIPRFFEGEKDMVGQAQTGSGKTAAFALPILD-LVDERSKDVQA 79 Query: 66 LYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPA 125 + I P + L + + ++ + + +G + + +++R +++ TP + Sbjct: 80 IVITPTRELALQVKDEIESLRGGKKVHVLAVYGGQPIFPQIERLRKGVQIVVGTPGRVID 139 Query: 126 LLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGNEE 185 L ++L L+ VRF V+DE ++D + I D RI A G E Sbjct: 140 HLERRTLS--LEKVRFFVLDEADRMLD-------------MGFIDDIERILRHA--GAER 182 Query: 186 EVKEWLGVDEIVKPPLKKRYK--FKVLFPRPR--PEDKELAELLRVDVEVAARLRTLWEI 241 V + L +RY ++V+ + PE+ E L+V+ E R L I Sbjct: 183 RVLMFSATMPPEVLRLARRYMRDYEVVRVHSKITPENVE-HRCLKVNPE--KRFEHLCRI 239 Query: 242 VEKHKRV-LVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALI 300 ++++ +VF T++ L RL+ G + +G + + R R ++G + L+ Sbjct: 240 LDENNFYGIVFCQTKKETRELGRRLRARGYKADALNGDIPQHKRESILRNFRKGYTRVLV 299 Query: 301 CTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 T GID+ ++ V+ Y P+ I R GR+ Sbjct: 300 ATDVAARGIDVKDLTHVVNYSIPQDPEAYIHRTGRT 335 >pir||H82390 ATP-dependent RNA helicase, DEAD box family VCA0990 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9658432|gb|AAF96886.1| (AE004426) ATP-dependent RNA helicase, DEAD box family [Vibrio cholerae] Length = 428 Score = 74.5 bits (180), Expect = 5e-12 Identities = 78/334 (23%), Positives = 140/334 (41%), Gaps = 20/334 (5%) Query: 5 LKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPIS 64 L +A+ + E + +Q + GK V +A TGSGKT A LP++ + P Sbjct: 34 LIQALPKAITEPSAIQTLVIPAMLTGKDVFALANTGSGKTLAYGLPLLERLKTS--PEQQ 91 Query: 65 CLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLP 124 L + P + L + E L G+ G + + + P++L+ T L Sbjct: 92 ALVLVPTRELAMQVSEVLTHVGTALGLNTLCLCGGVDKTEQQNALAENPNILVATTGRLF 151 Query: 125 ALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGNE 184 L T LR L V +V+DE L+D Q+ + + + + SAT ++ Sbjct: 152 DL-TQSGLR--LNRVTTLVLDEADRLLDMGFWPQVQALASQTAGVRQTVMC--SATFSDD 206 Query: 185 EEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEK 244 ++K ++++ P + + P + + V ++ + L ++++ Sbjct: 207 LKLK----AQQLMRAPTQ-------VSANPENSINQAVQETLYLVNKGSKTQALVALLKQ 255 Query: 245 HK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICT 302 H+ +VLVF+ ++ A+ L +L G V HG S+ R A + K G + LI T Sbjct: 256 HQWPQVLVFIGAKENADSLTKKLNKAGIVATVLHGDKSQSEREAALAEFKNGTTQVLIAT 315 Query: 303 SSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 + GI I + VI + P + R GR+ Sbjct: 316 DLLARGIHIELLPVVINFELPMHAETYVHRVGRT 349 >sp|P41377|IF42_ARATH EUKARYOTIC INITIATION FACTOR 4A-2 (EIF-4A-2) (EIF4A-2) >gi|322504|pir||JC1453 translation initiation factor eIF-4A2 - Arabidopsis thaliana >gi|16556|emb|CAA46189.1| (X65053) eukaryotic translation initiation factor 4A-2 [Arabidopsis thaliana] >gi|4585969|gb|AAD25605.1|AC005287_7 (AC005287) Eukaryotic Initiation Factor 4A-2 [Arabidopsis thaliana] Length = 412 Score = 74.1 bits (179), Expect = 6e-12 Identities = 77/338 (22%), Positives = 147/338 (42%), Gaps = 23/338 (6%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q +G V+ A +G+GKT V+ L L Sbjct: 50 LLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGVLQQ-LDYALLQC 108 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L +AP + L + + + ++ G+++ G T+ + ++ HV++ TP + Sbjct: 109 QALVLAPTRELAQQIEKVMRALGDYQGVKVHACVGGTSVREDQRILQAGVHVVVGTPGRV 168 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 +L +SLRP ++ V+DE E++ Q+ L+ I++G+ + Sbjct: 169 FDMLRRQSLRPDC--IKMFVLDEADEMLSRGFKDQIY---DIFQLLPPKIQVGVFSATMP 223 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA---RLRTLWE 240 E + EI + + K + V + ++ L + + V V +L TL + Sbjct: 224 PEAL-------EITRKFMSKPVRILV-----KRDELTLEGIKQFYVNVEKEDWKLETLCD 271 Query: 241 IVEKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKA 298 + E + ++FVNTR+ + L ++++ V HG + + R R+ + G + Sbjct: 272 LYETLAITQSVIFVNTRRKVDWLTDKMRSRDHTVSATHGDMDQNTRDIIMREFRSGSSRV 331 Query: 299 LICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 LI T + GID+ +V VI + P Q + R GRS Sbjct: 332 LITTDLLARGIDVQQVSLVINFDLPTQPENYLHRIGRS 369 >sp|Q10202|YBX6_SCHPO PUTATIVE ATP-DEPENDENT RNA HELICASE C17D1.06 >gi|2130219|pir||S67386 probable ATP-dependent RNA helicase - fission yeast (Schizosaccharomyces pombe) >gi|7492421|pir||T39709 probable atp-dependent rna helicase - fission yeast (Schizosaccharomyces pombe) >gi|3451298|emb|CAA20430.1| (AL031322) putative atp-dependent rna helicase [Schizosaccharomyces pombe] Length = 578 Score = 74.1 bits (179), Expect = 6e-12 Identities = 88/350 (25%), Positives = 149/350 (42%), Gaps = 38/350 (10%) Query: 5 LKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSI--LKDGLPP 62 L++ +K ++E +Q + + G+ V+ IA TGSGKT A +P + + L D Sbjct: 178 LREGLKN-YKEPTPIQAATWPYLLAGRDVVGIAETGSGKTVAFGIPALQYLNGLSDNKSV 236 Query: 63 ISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPET 122 L ++P + L E L T ++ V +G + +A+ +N V+I TP Sbjct: 237 PRVLVVSPTRELAIQTYENLNSLIQGTNLKAVVVYGGAPKSEQARAAKN-ASVIIGTPGR 295 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATV- 181 L L+ S+ V ++V+DE ++D Q I N+ +S D R G TV Sbjct: 296 LLDLINDGSID--CSQVGYLVLDEADRMLDT-GFEQDIRNI--ISHTPDPTRNGSRQTVF 350 Query: 182 ---------------GNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLR 226 ++ VK +G DE+ + + + PR +++ L LLR Sbjct: 351 FSATWPESVRALAATFLKDPVKITIGSDELAAS--QNITQIVEILDDPRSKERMLDNLLR 408 Query: 227 VDVEVAARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIE 286 + K ++L+FV ++ A + L V + HG +S+ AR++ Sbjct: 409 KHLSSGG----------KDDKILIFVLYKKEAARVEGTLARKYNVVGI-HGDMSQGARLQ 457 Query: 287 AERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 A K GK L+ T G+DI +V VI P + + R GR+ Sbjct: 458 ALNDFKSGKCPVLVATDVAARGLDIPKVQLVINVTFPLTIEDYVHRIGRT 507 >dbj|BAB10456.1| (AB005234) RNA helicase [Arabidopsis thaliana] Length = 522 Score = 74.1 bits (179), Expect = 6e-12 Identities = 89/376 (23%), Positives = 156/376 (40%), Gaps = 37/376 (9%) Query: 7 KAIKEK-FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILK-------D 58 KAIK+ + + +Q I +GK VL A TG+GKT A +LP + ++K + Sbjct: 67 KAIKDAGYETMTVVQEATLPIILKGKDVLAKAKTGTGKTVAFLLPSIEVVVKSPPTSPDN 126 Query: 59 GLPPISCLYIAPLKAL-NRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVR-NPPHVL 116 PPI L I P + L N+ E + I + V G T K+++ NP +L Sbjct: 127 KRPPILALVICPTRELANQAATEANTLLKYHPSIGVQVVIGGTRLGLEQKRMQTNPCQIL 186 Query: 117 ITTPETLPALL-TVKSLRPYLKNVRFVVVDEVTELIDN--KRGAQLILNL---KRLSLIA 170 + TP L + LK V+ +V+DE L+D ++ + I++ +R + + Sbjct: 187 VATPGRLKDHIENTPGFATRLKGVKVLVLDEADHLLDMGFRKDIERIISAVPKERQTFL- 245 Query: 171 DFIRIGLSATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVE 230 SATV E V +I L++ ++F E + + + Sbjct: 246 ------FSATVPEE--------VRQICLVALRRDHEFVNCVHEGTIETHQQVRQMHMIAS 291 Query: 231 VAARLRTLWEIVEKH------KRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEAR 284 + L+ ++ +H +V+VF T +++A L V H + R Sbjct: 292 LDRHFSLLYTLLREHIMGNVDYKVIVFCTTAMVTKLVADLLGELNLNVREIHSRKPQSYR 351 Query: 285 IEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVS 344 + ++ K L+ + G+D +V V+Q P+ + I R GR+ + E Sbjct: 352 TRVSNEFRKSKGLILVTSDVSARGVDYPDVTLVLQVGLPKDREQYIHRLGRTGRKGKEGE 411 Query: 345 EAYIIATGVEDYLQSL 360 ++A E +L SL Sbjct: 412 GILLLAPWEEYFLSSL 427 >gb|AAF47376.1| (AE003468) CG6994 gene product [Drosophila melanogaster] Length = 1390 Score = 74.1 bits (179), Expect = 6e-12 Identities = 108/481 (22%), Positives = 178/481 (36%), Gaps = 77/481 (16%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILK-DGLPP 62 L+K K ++ +Q + I EG+ V+ +A TGSGKT ++P+ + + + Sbjct: 613 LIKGITKRGYKVPTPIQRKTIPLILEGRDVVAMAKTGSGKTACFLIPLFEKLQRREPTKG 672 Query: 63 ISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPET 122 L ++P + L + +K ++ + G + + + P V++ TP Sbjct: 673 ARALILSPTRELAVQTYKFIKELGRFMELKSILVLGGDSMDSQFSAIHTCPDVIVATPGR 732 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRL--------------SL 168 L L+ L ++ +VV DE L + G QL L RL L Sbjct: 733 FLHLCVEMDLK--LNSIEYVVFDEADRLFEMGFGEQLNETLHRLPSSRQTVMFSATLPKL 790 Query: 169 IADFIRIGLSATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVD 228 + +F R GL+ V + +D V+ L K L+ RP L LL+ Sbjct: 791 LVEFARAGLNDPV--------LIRLD--VESKLPDALALKFLYCRPDDRYTALVVLLKYV 840 Query: 229 VEVAARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAE 288 + V ++ +VF T+ E++++ L G + SL AR Sbjct: 841 IPVQSQ-------------TVVFAGTQHHVELISYILTEAGISNASVYSSLDPAARKINT 887 Query: 289 RKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYI 348 K KV LI T GIDI +D V+ P + + R GR R AY Sbjct: 888 AKFVNKKVSVLIVTDVAARGIDIPSLDFVVNLHFPGKPKLFVHRVGRCA-RAGRTGTAYS 946 Query: 349 IATGVEDYLQSLIIAKRAIEGKLERIKPYENALDVLAHFIVGLLIEYQKLNVHEPYRMAK 408 I + D AH + L + N+H+ A Sbjct: 947 IV-----------------------------STDDTAHLLDLHLFLNRPFNIHD--SSAL 975 Query: 409 ETYPYRNLKWEHYLEVINVLEDAGIIRREEGILKLGRRAFKYYFDNLSTIPDEVSYKVVD 468 T P L+ EH L V ++ + I G+L+ A+K Y + + + +V Sbjct: 976 GTIPQDLLEEEH-LTVTDIKKSHHI----AGVLRTSENAYKKYLSSRPVASTDANARVKK 1030 Query: 469 I 469 I Sbjct: 1031 I 1031 >emb|CAA73167.1| (Y12590) translation initiation factor eIF4A I [Xenopus laevis] Length = 406 Score = 73.7 bits (178), Expect = 8e-12 Identities = 78/338 (23%), Positives = 147/338 (43%), Gaps = 24/338 (7%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q A +G V+ A +G+GKT + ++ I D + Sbjct: 43 LLRGIYAYGFEKPSAIQQRAIMPCIKGYDVIAQAQSGTGKTATFAISILQQIELD-MKAT 101 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNP-PHVLITTPET 122 L +AP + L + + + + G G T +++++ PH+++ TP Sbjct: 102 QALVLAPTRELAQQIQKVVMALGDYMGAGCHACIGGTDVRAEVQKLQSEAPHIVVGTPGR 161 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVG 182 + +L + L P K ++ V+DE E++ Q+ ++LS A + LSAT+ Sbjct: 162 VFDMLNRRYLSP--KYIKMFVLDEADEMLSRGFKDQIYDIFQKLSSNAQVVL--LSATMP 217 Query: 183 NEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA---RLRTLW 239 + V E+ K ++ + V + E+ L + + + V +L TL Sbjct: 218 AD--------VLEVTKKFMRDPIRILV-----KKEELTLEGIRQFYINVEREEWKLDTLC 264 Query: 240 EIVEKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVK 297 ++ E + ++F+NTR+ + L ++ V HG + ++ R R+ + G + Sbjct: 265 DLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSR 324 Query: 298 ALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGR 335 LI T + GID+ +V VI Y P I R GR Sbjct: 325 VLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGR 362 >pir||S13269 translation initiation factor eIF-4A.I - rabbit (fragment) Length = 398 Score = 73.7 bits (178), Expect = 8e-12 Identities = 77/338 (22%), Positives = 146/338 (42%), Gaps = 24/338 (7%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q A +G V+ A +G+GKT + ++ I D L Sbjct: 35 LLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELD-LKAT 93 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVR-NPPHVLITTPET 122 L +AP + L + + + + G G T ++++ PH+++ TP Sbjct: 94 QALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGR 153 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVG 182 + +L + L P K ++ V+DE E++ Q+ ++L+ + LSAT+ Sbjct: 154 VFDMLNRRYLSP--KYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVL--LSATMP 209 Query: 183 NEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA---RLRTLW 239 ++ V E+ K ++ + V + E+ L + + + V +L TL Sbjct: 210 SD--------VLEVTKKFMRDPIRILV-----KKEELTLEGIRQFYINVEREEWKLDTLC 256 Query: 240 EIVEKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVK 297 ++ E + ++F+NTR+ + L ++ V HG + ++ R R+ + G + Sbjct: 257 DLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSR 316 Query: 298 ALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGR 335 LI T + GID+ +V VI Y P I R GR Sbjct: 317 VLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGR 354 >emb|CAA26842.1| (X03039) put. eIF-4A (aa 1-390) [Mus musculus] >gi|50819|emb|CAA26845.1| (X03040) put. eIF-4A (aa 1-390) [Mus musculus] Length = 390 Score = 73.7 bits (178), Expect = 8e-12 Identities = 77/338 (22%), Positives = 146/338 (42%), Gaps = 24/338 (7%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q A +G V+ A +G+GKT + ++ I D L Sbjct: 27 LLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELD-LKAT 85 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVR-NPPHVLITTPET 122 L +AP + L + + + + G G T ++++ PH+++ TP Sbjct: 86 QALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGR 145 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVG 182 + +L + L P K ++ V+DE E++ Q+ ++L+ + LSAT+ Sbjct: 146 VFDMLNRRYLSP--KYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVL--LSATMP 201 Query: 183 NEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA---RLRTLW 239 ++ V E+ K ++ + V + E+ L + + + V +L TL Sbjct: 202 SD--------VLEVTKKFMRDPIRILV-----KKEELTLEGIRQFYINVEREEWKLDTLC 248 Query: 240 EIVEKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVK 297 ++ E + ++F+NTR+ + L ++ V HG + ++ R R+ + G + Sbjct: 249 DLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSR 308 Query: 298 ALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGR 335 LI T + GID+ +V VI Y P I R GR Sbjct: 309 VLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGR 346 >emb|CAA26843.1| (X03039) put. altern. eIF-4A (aa 1-370) [Mus musculus] >gi|50820|emb|CAA26846.1| (X03040) put. altern. eIF-4A (aa 1-370) [Mus musculus] Length = 370 Score = 73.7 bits (178), Expect = 8e-12 Identities = 77/338 (22%), Positives = 146/338 (42%), Gaps = 24/338 (7%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q A +G V+ A +G+GKT + ++ I D L Sbjct: 7 LLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELD-LKAT 65 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVR-NPPHVLITTPET 122 L +AP + L + + + + G G T ++++ PH+++ TP Sbjct: 66 QALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGR 125 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVG 182 + +L + L P K ++ V+DE E++ Q+ ++L+ + LSAT+ Sbjct: 126 VFDMLNRRYLSP--KYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVL--LSATMP 181 Query: 183 NEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA---RLRTLW 239 ++ V E+ K ++ + V + E+ L + + + V +L TL Sbjct: 182 SD--------VLEVTKKFMRDPIRILV-----KKEELTLEGIRQFYINVEREEWKLDTLC 228 Query: 240 EIVEKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVK 297 ++ E + ++F+NTR+ + L ++ V HG + ++ R R+ + G + Sbjct: 229 DLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSR 288 Query: 298 ALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGR 335 LI T + GID+ +V VI Y P I R GR Sbjct: 289 VLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGR 326 >pir||S00986 translation initiation factor eIF-4A I - mouse Length = 407 Score = 73.7 bits (178), Expect = 8e-12 Identities = 78/338 (23%), Positives = 146/338 (43%), Gaps = 24/338 (7%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q A +G V+ A +G+GKT + ++ I D L Sbjct: 44 LLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELD-LKAT 102 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVR-NPPHVLITTPET 122 L +AP + L + + + + G G T ++++ PH++I TP Sbjct: 103 QALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIVIGTPGR 162 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVG 182 + +L + L P K ++ V+DE E++ Q+ ++L+ + LSAT+ Sbjct: 163 VFDMLNRRYLSP--KYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVL--LSATMP 218 Query: 183 NEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA---RLRTLW 239 ++ V E+ K ++ + V + E+ L + + + V +L TL Sbjct: 219 SD--------VLEVTKKFMRDPIRILV-----KKEELTLEGIRQFYINVEREEWKLDTLC 265 Query: 240 EIVEKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVK 297 ++ E + ++F+NTR+ + L ++ V HG + ++ R R+ + G + Sbjct: 266 DLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSR 325 Query: 298 ALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGR 335 LI T + GID+ +V VI Y P I R GR Sbjct: 326 VLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGR 363 >gi|4503529 eukaryotic translation initiation factor 4A, isoform 1 [Homo sapiens] >gi|417180|sp|P04765|IF41_HUMAN EUKARYOTIC INITIATION FACTOR 4A-I (EIF-4A-I) >gi|422959|pir||S33681 translation initiation factor eIF-4A.I - human >gi|7428973|pir||FIMS4A translation initiation factor eIF-4A I - mouse >gi|219403|dbj|BAA02897.1| (D13748) eukaryotic initiation factor 4AI [Homo sapiens] >gi|2943740|dbj|BAA25075.1| (AB011595) eIF4A [Mus musculus] >gi|227238|prf||1617105B initiation factor 4AI [Oryctolagus cuniculus] Length = 406 Score = 73.7 bits (178), Expect = 8e-12 Identities = 77/338 (22%), Positives = 146/338 (42%), Gaps = 24/338 (7%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q A +G V+ A +G+GKT + ++ I D L Sbjct: 43 LLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELD-LKAT 101 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVR-NPPHVLITTPET 122 L +AP + L + + + + G G T ++++ PH+++ TP Sbjct: 102 QALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGR 161 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVG 182 + +L + L P K ++ V+DE E++ Q+ ++L+ + LSAT+ Sbjct: 162 VFDMLNRRYLSP--KYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVL--LSATMP 217 Query: 183 NEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA---RLRTLW 239 ++ V E+ K ++ + V + E+ L + + + V +L TL Sbjct: 218 SD--------VLEVTKKFMRDPIRILV-----KKEELTLEGIRQFYINVEREEWKLDTLC 264 Query: 240 EIVEKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVK 297 ++ E + ++F+NTR+ + L ++ V HG + ++ R R+ + G + Sbjct: 265 DLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSR 324 Query: 298 ALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGR 335 LI T + GID+ +V VI Y P I R GR Sbjct: 325 VLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGR 362 >sp|P29562|IF41_RABIT EUKARYOTIC INITIATION FACTOR 4A-I (EIF-4A-I) (EIF4A-I) Length = 394 Score = 73.7 bits (178), Expect = 8e-12 Identities = 77/338 (22%), Positives = 146/338 (42%), Gaps = 24/338 (7%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q A +G V+ A +G+GKT + ++ I D L Sbjct: 31 LLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELD-LKAT 89 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVR-NPPHVLITTPET 122 L +AP + L + + + + G G T ++++ PH+++ TP Sbjct: 90 QALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGR 149 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVG 182 + +L + L P K ++ V+DE E++ Q+ ++L+ + LSAT+ Sbjct: 150 VFDMLNRRYLSP--KYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVL--LSATMP 205 Query: 183 NEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA---RLRTLW 239 ++ V E+ K ++ + V + E+ L + + + V +L TL Sbjct: 206 SD--------VLEVTKKFMRDPIRILV-----KKEELTLEGIRQFYINVEREEWKLDTLC 252 Query: 240 EIVEKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVK 297 ++ E + ++F+NTR+ + L ++ V HG + ++ R R+ + G + Sbjct: 253 DLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSR 312 Query: 298 ALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGR 335 LI T + GID+ +V VI Y P I R GR Sbjct: 313 VLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGR 350 >sp|P34640|YOQ2_CAEEL PUTATIVE ATP-DEPENDENT RNA HELICASE ZK512.2 IN CHROMOSOME III >gi|3881691|emb|CAA80151.1| (Z22177) similar to RNA binding proteins (helicase etc.), contains similarity to Pfam domain: PF00270 (DEAD/DEAH box helicase), Score=160.4, E-value=2.8e-50, N=1; PF00271 (Helicases conserved C-terminal domain), Score=101.9, E-value=4e-27, N=1~cDNA EST> Length = 578 Score = 73.7 bits (178), Expect = 8e-12 Identities = 86/383 (22%), Positives = 164/383 (42%), Gaps = 29/383 (7%) Query: 5 LKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP-- 62 L + + ++ +Q+ + + V++ +PTGSGKT A +LP+M I L P Sbjct: 21 LLEVFDKSYKSFTDVQVLSGTHLLNLSDVVVESPTGSGKTLAFVLPMMRMIQNAKLQPAD 80 Query: 63 ISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPP-HVLITTPE 121 I L ++P + L ++ ++ + K + ++ G + K +N ++L+ TP Sbjct: 81 IGALILSPSRELCSQIVSVIQPFAEKLNLTVETVTGGQKVDKNIKMFKNKNVNILVATPG 140 Query: 122 TLPALLTVKS--LRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKR-LSLIADFIRIGLS 178 L ++ + + ++ ++ +V+DE D Q +++ LS I R GL Sbjct: 141 RLFQIIQHEKTLIARKMRTLQLLVIDEA----DRFNEIQFEDHMREILSCIPKQRRTGLF 196 Query: 179 ATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRTL 238 + +EE D+++ L+ + KV R L V+ + Sbjct: 197 SATQVKEE-------DDLMVFGLRNAKQVKVAQERNSAAPSTLKNYY-VECRADEKTSVC 248 Query: 239 WEIVEKH--KRVLVFV----NTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLK 292 E + + K++L+F + R F ++ L +P+ HG S R + Sbjct: 249 LEFIRQRTDKKILIFFPSCNSVRYFYKIFERCLGK--RPLFAVHGKCSNPHRASQIKAFS 306 Query: 293 EGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATG 352 + +I T M GIDI ++D VIQ+ P+ + + RAGR+ E + +IA+ Sbjct: 307 DSTNGVMISTDVMARGIDISDIDWVIQFDLPKHSSWFVHRAGRTARCGREGNALILIASE 366 Query: 353 VEDYLQSLIIAKRAIEGKLERIK 375 Y+ L ++ KL+ IK Sbjct: 367 QLAYVNFLDNHEKV---KLDEIK 386 >gb|AAB39865.1| (U81597) ATP-dependent RNA helicase [Leishmania amazonensis] Length = 855 Score = 73.4 bits (177), Expect = 1e-11 Identities = 75/341 (21%), Positives = 148/341 (42%), Gaps = 21/341 (6%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSI-LKDGLPP 62 LL +K+ F +Q +A + +G V+ +A TGSGKT A ++P++N++ + Sbjct: 35 LLDAILKQGFSVPTPIQRKAIPPMLQGNDVVAMARTGSGKTAAFLIPMLNTLKAHSKIVG 94 Query: 63 ISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPET 122 I L ++P + L+ +L +R G + ++ + + + P +++ TP Sbjct: 95 IRGLVLSPTRELSLQILRNGFALNKFLDLRFAALVGGDSMDQQFELLASNPDIVVATPGR 154 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVG 182 L ++ SL +L +VR +V+DE L + Q+ +++L + Sbjct: 155 LLHIMEEASL--HLTSVRCLVLDEADRLFELGLQPQIGAIMQKLPESCQRALFSATMPTV 212 Query: 183 NEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA------RLR 236 E WL +++ + + ++ K+ A L+R D +VAA R+ Sbjct: 213 LAEFTSAWLHNPVVIRLDSEMKLSDQL---------KQSAFLVRNDEKVAALIVLLKRVL 263 Query: 237 TLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKL--KEG 294 + E + + L+FV ++ E L L + HG + +EAR A R +E Sbjct: 264 HVGEAAANNAQALIFVESKFHVEFLLMILTAYSISTSAVHGQMDQEARRLAVRSFAKRES 323 Query: 295 KVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGR 335 V + ++ G+D+ +D ++ + P + R GR Sbjct: 324 SVMVVTDVAARGYGLDL-LLDNIVYFSFPFNPKLFVHRVGR 363 >dbj|BAB01768.1| (AB022215) DEAD-Box RNA helicase-like protein [Arabidopsis thaliana] Length = 610 Score = 73.4 bits (177), Expect = 1e-11 Identities = 82/343 (23%), Positives = 152/343 (43%), Gaps = 33/343 (9%) Query: 7 KAIKEK-FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILK------DG 59 KA+K + +L +Q + EG+ ++ A TG+GKT A +P+++ I+K G Sbjct: 129 KALKGRGIEKLFPIQKAVLEPAMEGRDMIGRARTGTGKTLAFGIPIIDKIIKFNAKHGRG 188 Query: 60 LPPISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITT 119 P CL +AP + L R + + + E+ + +G T ++ +++ V + T Sbjct: 189 KNP-QCLVLAPTRELARQVEKEFR--ESAPSLDTICLYGGTPIGQQMRELNYGIDVAVGT 245 Query: 120 PETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSA 179 P + L+ +L L V+FVV+DE +++ + + L++L A + SA Sbjct: 246 PGRIIDLMKRGALN--LSEVQFVVLDEADQMLQVGFAEDVEIILQKLP--AKRQSMMFSA 301 Query: 180 TVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAE---LLRVDVEVAARLR 236 T+ + W ++ KK + D++LA+ + + + R Sbjct: 302 TMPS------W------IRSLTKKYLNNPLTIDLVGDSDQKLADGITMYSIAADSYGRAS 349 Query: 237 TLWEIVEKHKR---VLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKE 293 + +V++H + +VF T++ A+ LA L K E HG +S+ R ++ Sbjct: 350 IIGPLVKEHGKGGKCIVFTQTKRDADRLAFGLAKSYK-CEALHGDISQAQRERTLAGFRD 408 Query: 294 GKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 G L+ T G+D+ VD VI Y P + R GR+ Sbjct: 409 GNFSILVATDVAARGLDVPNVDLVIHYELPNNTETFVHRTGRT 451 >emb|CAA73168.1| (Y12591) translation initiation factor eIF4A II [Xenopus laevis] Length = 413 Score = 73.0 bits (176), Expect = 1e-11 Identities = 79/339 (23%), Positives = 148/339 (43%), Gaps = 25/339 (7%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q A +G V+ A +G+GKT + ++ I D + Sbjct: 49 LLRGIYAYGFEKPSAIQQRAIMPCIKGYDVIAQAQSGTGKTATFAISILQQIELD-MKAT 107 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNP-PHVLITTPET 122 L +AP + L + + + + G G T +++++ PH+++ TP Sbjct: 108 QALMLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQSEAPHIIVGTPGR 167 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLI-LNLKRLSLIADFIRIGLSATV 181 + +L + L P K ++ V+DE E++ Q+ + K LS+ A + LSAT+ Sbjct: 168 VFDMLNRRYLSP--KYIKMFVLDEADEMLSRGFKDQIYDIFQKVLSMNAQVVL--LSATM 223 Query: 182 GNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA---RLRTL 238 + V E+ K ++ + V + E+ L + + + V +L TL Sbjct: 224 PAD--------VLEVTKKFMRDPIRILV-----KKEELTLEGIRQFYINVEREEWKLDTL 270 Query: 239 WEIVEKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKV 296 ++ E + ++F+NTR+ + L ++ V HG + ++ R R+ + G Sbjct: 271 CDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSS 330 Query: 297 KALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGR 335 + LI T + GID+ +V VI Y P I R GR Sbjct: 331 RVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGR 369 >dbj|BAA28347.1| (AB010259) DRH1 [Arabidopsis thaliana] >gi|6016713|gb|AAF01539.1|AC009325_9 (AC009325) RNA helicase, DRH1 [Arabidopsis thaliana] Length = 619 Score = 73.0 bits (176), Expect = 1e-11 Identities = 78/378 (20%), Positives = 159/378 (41%), Gaps = 21/378 (5%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILP---VMNSILKDGL 60 LL++ + F +Q +++ +G+ ++ IA TGSGKT ++P + I D Sbjct: 169 LLREVLSAGFSAPTPIQAQSWPIAMQGRDIVAIAKTGSGKTLGYLIPGFLHLQRIRNDSR 228 Query: 61 PPISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTP 120 + L ++P + L + E + + I +G + + + + +++ TP Sbjct: 229 MGPTILVLSPTRELATQIQEEAVKFGRSSRISCTCLYGGAPKGPQLRDLERGADIVVATP 288 Query: 121 ETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSAT 180 L +L ++ R L+ + ++V+DE ++D Q+ +K + R L T Sbjct: 289 GRLNDILEMR--RISLRQISYLVLDEADRMLDMGFEPQIRKIVKEIPT----KRQTLMYT 342 Query: 181 VGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRV--DVEVAARLRTL 238 + V++ + D +V P L +K + + + V +E RL + Sbjct: 343 ATWPKGVRK-IAADLLVNPAQVNIGNVDELV-----ANKSITQHIEVVAPMEKQRRLEQI 396 Query: 239 WEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKA 298 E +V++F +T++ + L L + HG S+ R + + G+ Sbjct: 397 LRSQEPGSKVIIFCSTKRMCDQLTRNLTRQFGAAAI-HGDKSQPERDNVLNQFRSGRTPV 455 Query: 299 LICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQ 358 L+ T G+D+ ++ AV+ Y P V + R GR+ R +A+ + Sbjct: 456 LVATDVAARGLDVKDIRAVVNYDFPNGVEDYVHRIGRT-GRAGATGQAFTFFGDQDSKHA 514 Query: 359 SLIIAKRAIEGKLERIKP 376 S +I + +EG +R+ P Sbjct: 515 SDLI--KILEGANQRVPP 530 >gi|6320400 Mitochondrial DEAD box RNA helicase; Mss116p [Saccharomyces cerevisiae] >gi|127324|sp|P15424|MS16_YEAST ATP-DEPENDENT RNA HELICASE MSS116 PRECURSOR >gi|83510|pir||S02116 RNA helicase MSS116 - yeast (Saccharomyces cerevisiae) >gi|755787|emb|CAA88707.1| (Z48784) Mss116p [Saccharomyces cerevisiae] Length = 664 Score = 72.6 bits (175), Expect = 2e-11 Identities = 96/408 (23%), Positives = 168/408 (40%), Gaps = 52/408 (12%) Query: 6 KKAIKEKFRELNRLQIEAFKRI--SEGKSVLIIAPTGSGKTEAAILPVMNSILK---DGL 60 K + +F L +Q + K I SE V+ A TG+GKT A ++P+ ++ D Sbjct: 119 KAITRMEFPGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTFAFLIPIFQHLINTKFDSQ 178 Query: 61 PPISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHG----------DTTQYRRAKQVR 110 + + +AP RDL ++ EA+ D+ +G T +R A Sbjct: 179 YMVKAVIVAP----TRDLALQI---EAEVKKIHDMNYGLKKYACVSLVGGTDFRAAMNKM 231 Query: 111 NP--PHVLITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELI-----DNKRGAQLILNL 163 N P+++I TP L +L K + + V + V+DE L+ D+ ILN Sbjct: 232 NKLRPNIVIATPGRLIDVLE-KYSNKFFRFVDYKVLDEADRLLEIGFRDDLETISGILNE 290 Query: 164 KRLSLIADFIRIGLSATVGNEEEV--------KEWLGVDEIVK--PPLKKRYKFKVLFPR 213 K + + SAT+ ++ + KE L +D + K P +R V+ Sbjct: 291 KNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHERIDQSVVISE 350 Query: 214 PRPEDKELAELLRVDVEVAARLRTLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGK--- 270 + + A + + ++ R + + + ++F T +F L LK K Sbjct: 351 -KFANSIFAAVEHIKKQIKER--------DSNYKAIIFAPTVKFTSFLCSILKNEFKKDL 401 Query: 271 PVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLI 330 P+ HG +++ R ++ K+ + L+CT G+D V V+Q P ++ I Sbjct: 402 PILEFHGKITQNKRTSLVKRFKKDESGILVCTDVGARGMDFPNVHEVLQIGVPSELANYI 461 Query: 331 QRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIKPYE 378 R GR+ E S I +++ L AK + K E+ +P E Sbjct: 462 HRIGRTARSGKEGSSVLFICKDELPFVRELEDAKNIVIAKQEKYEPSE 509 >pir||T51347 RNA helicase RH23 [imported] - Arabidopsis thaliana (fragment) >gi|3776021|emb|CAA09211.1| (AJ010472) RNA helicase [Arabidopsis thaliana] Length = 441 Score = 72.6 bits (175), Expect = 2e-11 Identities = 77/336 (22%), Positives = 147/336 (42%), Gaps = 19/336 (5%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q +G V+ A +G+GKT V+ L L Sbjct: 79 LLRGIYAYGFEKPSAIQQRGIIPFCKGLDVIQQAQSGTGKTATFCSGVLQQ-LDISLVQC 137 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L +AP + L + + + ++ G++ G T+ + +++ HV++ TP + Sbjct: 138 QALVLAPTRELAQQIEKVMRALGDYLGVKAQACVGGTSVREDQRVLQSGVHVVVGTPGRV 197 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 LL +SLR ++ V+DE E++ Q+ L+ +++G+ + Sbjct: 198 FDLLRRQSLRA--DAIKMFVLDEADEMLSRGFKDQIY---DIFQLLPSKVQVGVFSATMP 252 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAEL-LRVDVEVAARLRTLWEIV 242 E + EI + + K ++L R + + + + VD E +L TL ++ Sbjct: 253 PEAL-------EITRKFMNK--PVRILVKRDELTLEGIKQFYVNVDKE-EWKLETLCDLY 302 Query: 243 EKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALI 300 E + ++FVNTR+ + L ++++ V HG + + R R+ + G + LI Sbjct: 303 ETLAITQSVIFVNTRRKVDWLTDKMRSRDHTVSATHGDMDQNTRDIIMREFRSGSSRVLI 362 Query: 301 CTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 T + GID+ +V VI + P Q + R GRS Sbjct: 363 TTDLLARGIDVQQVSLVINFDLPTQPENYLHRIGRS 398 >gb|AAF21155.1|AC010926_7 (AC010926) putative Eukaryotic initiation factor 4A; 30924-32477 [Arabidopsis thaliana] Length = 414 Score = 72.6 bits (175), Expect = 2e-11 Identities = 77/336 (22%), Positives = 147/336 (42%), Gaps = 19/336 (5%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q +G V+ A +G+GKT V+ L L Sbjct: 52 LLRGIYAYGFEKPSAIQQRGIIPFCKGLDVIQQAQSGTGKTATFCSGVLQQ-LDISLVQC 110 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L +AP + L + + + ++ G++ G T+ + +++ HV++ TP + Sbjct: 111 QALVLAPTRELAQQIEKVMRALGDYLGVKAQACVGGTSVREDQRVLQSGVHVVVGTPGRV 170 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 LL +SLR ++ V+DE E++ Q+ L+ +++G+ + Sbjct: 171 FDLLRRQSLRA--DAIKMFVLDEADEMLSRGFKDQIY---DIFQLLPSKVQVGVFSATMP 225 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAEL-LRVDVEVAARLRTLWEIV 242 E + EI + + K ++L R + + + + VD E +L TL ++ Sbjct: 226 PEAL-------EITRKFMNK--PVRILVKRDELTLEGIKQFYVNVDKE-EWKLETLCDLY 275 Query: 243 EKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALI 300 E + ++FVNTR+ + L ++++ V HG + + R R+ + G + LI Sbjct: 276 ETLAITQSVIFVNTRRKVDWLTDKMRSRDHTVSATHGDMDQNTRDIIMREFRSGSSRVLI 335 Query: 301 CTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 T + GID+ +V VI + P Q + R GRS Sbjct: 336 TTDLLARGIDVQQVSLVINFDLPTQPENYLHRIGRS 371 >gb|AAF54192.1| (AE003677) CG7878 gene product [Drosophila melanogaster] Length = 703 Score = 72.6 bits (175), Expect = 2e-11 Identities = 74/341 (21%), Positives = 149/341 (42%), Gaps = 22/341 (6%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP- 62 +L++ K F + + +Q +A+ + +G ++ IA TG+GKT A +LP M P Sbjct: 294 MLEEITKMGFSKPSPIQSQAWPILLQGHDMIGIAQTGTGKTLAFLLPGMIHTEYQSTPRG 353 Query: 63 ----ISCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLIT 118 + L +AP + L + +K + + G++ +G + + + ++I Sbjct: 354 TRGGANVLVLAPTRELALQIEMEVKKYSFR-GMKAVCVYGGGNRNMQISDLERGAEIIIC 412 Query: 119 TPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLS 178 TP L L+ + + + ++V+DE ++D G + + L + D I S Sbjct: 413 TPGRLNDLIMANVID--VSTITYLVLDEADRMLD--MGFEPQIRKVMLDIRPDRQTIMTS 468 Query: 179 ATVGNEEEVKEWL-GVDEIVKPPLKKRYKFKV--LFPRPRPEDKELAELLRVDVEVAARL 235 AT W GV + + +K + V L K++ +L+ D++ + Sbjct: 469 AT---------WPPGVRRLAQSYMKNPIQVCVGSLDLAATHSVKQIIKLMEDDMDKFNTI 519 Query: 236 RTLWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGK 295 + + + ++++F + A+ L+ L G + HG+ + R +A +K G Sbjct: 520 TSFVKNMSSTDKIIIFCGRKVRADDLSSELTLDGFMTQCIHGNRDQMDREQAIADIKSGV 579 Query: 296 VKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 V+ L+ T G+DI ++ VI Y P + + R GR+ Sbjct: 580 VRILVATDVASRGLDIEDITHVINYDFPHNIEEYVHRVGRT 620 >pir||JS0039 translation initiation factor eIF-4A - mouse >gi|556308|gb|AAA50407.1| (L36611) protein synthesis initiation factor 4A [Mus musculus] Length = 406 Score = 72.2 bits (174), Expect = 2e-11 Identities = 77/338 (22%), Positives = 146/338 (42%), Gaps = 24/338 (7%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q A +G V+ A +G+GKT + ++ I D L Sbjct: 43 LLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELD-LKAT 101 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVR-NPPHVLITTPET 122 L +AP + L + + + + G G T ++++ PH+++ TP Sbjct: 102 QALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGR 161 Query: 123 LPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVG 182 + +L + L P K ++ V+DE E++ Q+ ++L+ + LSAT+ Sbjct: 162 VFDMLNRRYLSP--KYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVL--LSATMP 217 Query: 183 NEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA---RLRTLW 239 ++ V E+ K ++ + V + E+ L + + + V +L TL Sbjct: 218 SD--------VLEVTKKFMRDPIRILV-----KKEELTLEGIRQFYINVEREEWKLDTLC 264 Query: 240 EIVEKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVK 297 ++ E + ++F+NTR+ + L ++ V HG + ++ R R+ + G + Sbjct: 265 DLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVCAMHGDMDQKERDVIMREFRSGSSR 324 Query: 298 ALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGR 335 LI T + GID+ +V VI Y P I R GR Sbjct: 325 VLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGR 362 >gi|6321267 RNA helicase involved in rRNA processing; Rok1p [Saccharomyces cerevisiae] >gi|1173121|sp|P45818|ROK1_YEAST ATP-DEPENDENT RNA HELICASE ROK1 >gi|2131186|pir||S59649 ATP-dependent RNA helicase ROK1 - yeast (Saccharomyces cerevisiae) >gi|607182|emb|CAA84384.1| (Z34901) ATP-dependent RNA helicase [Saccharomyces cerevisiae] >gi|971382|emb|CAA59758.1| (X85757) putative ATP dependent RNA helicase [Saccharomyces cerevisiae] >gi|1322774|emb|CAA96883.1| (Z72693) ORF YGL171w [Saccharomyces cerevisiae] Length = 564 Score = 72.2 bits (174), Expect = 2e-11 Identities = 83/348 (23%), Positives = 151/348 (42%), Gaps = 32/348 (9%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP- 62 LL I+ F E +Q E + VL PTGSGKT A ++P++ I+ D Sbjct: 133 LLNNLIENGFTEPTPIQCECIPVALNNRDVLACGPTGSGKTLAFLIPLVQQIIDDKQTAG 192 Query: 63 ISCLYIAPLKAL-NRDLLERLK-----WWEAKTGIRIDVRHGDTTQYRRAKQVRNPPH-V 115 + L I+P K L N+ +E K + E K +++ + + K V + + + Sbjct: 193 LKGLIISPTKELANQIFIECFKLSYKIFLEKKRPLQVALLSKSLGAKLKNKVVSDKKYDI 252 Query: 116 LITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDN---KRGAQLILNLKRLSLIADF 172 +I+TP L + VK+ L V+ ++ DE +L D ++ ++ + SL Sbjct: 253 IISTP--LRLIDVVKNEALDLSKVKHLIFDEADKLFDKTFVEQSDDILSACREPSLR--- 307 Query: 173 IRIGLSATV-GNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEV 231 + SAT+ N EE+ + + +D + +V+ + + + L Sbjct: 308 -KAMFSATIPSNVEEIAQSIMMDPV-----------RVIIGHKEAANTNIEQKLIFCGNE 355 Query: 232 AARLRTLWEIVEKHK---RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAE 288 +L + ++V++ + +++F+ + A+ L H L V+V H + R Sbjct: 356 EGKLIAIRQLVQEGEFKPPIIIFLESITRAKALYHELMYDRINVDVIHAERTALQRDRII 415 Query: 289 RKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 + K G++ LICT + GID V+ VI Y P + R GR+ Sbjct: 416 ERFKTGELWCLICTDVLARGIDFKGVNLVINYDVPGSSQAYVHRIGRT 463 >gb|AAF24007.1|AF083031_4 (AF083031) eukaryotic initiation factor 4a [Guillardia theta] Length = 385 Score = 72.2 bits (174), Expect = 2e-11 Identities = 81/339 (23%), Positives = 147/339 (42%), Gaps = 25/339 (7%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LLK F + +Q I + V+ + +G+GKT ++ + + L + I Sbjct: 23 LLKGIYGYGFERPSFIQQRGILPIINKEDVVAQSQSGTGKTATFVIGTLQN-LSNIENKI 81 Query: 64 SCLYIAPLKALNRDLLERLK----WWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITT 119 L + P + L + + K + + KT + + GD Q +Q + P ++I T Sbjct: 82 KNLVLVPTRELATQVEQVFKSIGFFMKIKTQL---LTGGDRIQITNKEQYKKP-QIVIGT 137 Query: 120 PETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSA 179 P + L+ K+ Y++N+ ++VVDE E+ Q++ +K L L A + Sbjct: 138 PGKVLDSLSKKTY--YIENLEYLVVDEADEMFSRGFKIQVLKIIKYLPLEAKIALFSATM 195 Query: 180 TVGNEEEVKEWLG--VDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAARLRT 237 + E V+ ++ V +VK K + E+ +L ++ + ++ Sbjct: 196 PIETLEIVELFMTNPVKILVKKDELTLEGIKQFYIAIEKEEWKLDSVIEIYSKI------ 249 Query: 238 LWEIVEKHKRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVK 297 K + +++VNTR+ E LA+ +K +G V HG + + R + + G + Sbjct: 250 ------KITQSIIYVNTRRKTEWLANIMKKYGFDVGYLHGEMLQIDRSSVMKDFRSGLFR 303 Query: 298 ALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 LI T + GIDI +V VI Y P+ I R GRS Sbjct: 304 ILISTDLVSRGIDIQQVCLVINYDLPKLKEVYIHRIGRS 342 >pir||S40763 hypothetical protein ZK512.2 - Caenorhabditis elegans Length = 578 Score = 71.8 bits (173), Expect = 3e-11 Identities = 84/355 (23%), Positives = 154/355 (42%), Gaps = 29/355 (8%) Query: 33 VLIIAPTGSGKTEAAILPVMNSILKDGLPP--ISCLYIAPLKALNRDLLERLKWWEAKTG 90 V++ +PTGSGKT A +LP+M I L P I L ++P + L ++ ++ + K Sbjct: 23 VVVESPTGSGKTLAFVLPMMRMIQNAKLQPADIGALILSPSRELCSQIVSVIQPFAEKLN 82 Query: 91 IRIDVRHGDTTQYRRAKQVRNPP-HVLITTPETLPALLTVKS--LRPYLKNVRFVVVDEV 147 + ++ G + K +N ++L+ TP L ++ + + ++ ++ +V+DE Sbjct: 83 LTVETVTGGQKVDKNIKMFKNKNVNILVATPGRLFQIIQHEKTLIARKMRTLQLLVIDEA 142 Query: 148 TELIDNKRGAQLILNLKR-LSLIADFIRIGLSATVGNEEEVKEWLGVDEIVKPPLKKRYK 206 D Q +++ LS I R GL + +EE D+++ L+ + Sbjct: 143 ----DRFNEIQFEDHMREILSCIPKQRRTGLFSATQVKEE-------DDLMVFGLRNAKQ 191 Query: 207 FKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEKH--KRVLVFV----NTRQFAEV 260 KV R L V+ + E + + K++L+F + R F ++ Sbjct: 192 VKVAQERNSAAPSTLKNYY-VECRADEKTSVCLEFIRQRTDKKILIFFPSCNSVRYFYKI 250 Query: 261 LAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQY 320 L +P+ HG S R + + +I T M GIDI ++D VIQ+ Sbjct: 251 FERCLGK--RPLFAVHGKCSNPHRASQIKAFSDSTNGVMISTDVMARGIDISDIDWVIQF 308 Query: 321 MSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIK 375 P+ + + RAGR+ E + +IA+ Y+ L ++ KL+ IK Sbjct: 309 DLPKHSSWFVHRAGRTARCGREGNALILIASEQLAYVNFLDNHEKV---KLDEIK 360 >gb|AAD55444.1|AF181659_1 (AF181659) BcDNA.GM05306 [Drosophila melanogaster] Length = 641 Score = 71.8 bits (173), Expect = 3e-11 Identities = 97/382 (25%), Positives = 165/382 (42%), Gaps = 32/382 (8%) Query: 30 GKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISC---LYIAPLKALNRDLLERLKWWE 86 G+ + A TG+GKT A +LP + +L L + L + P + L + + K Sbjct: 194 GRDICGCAATGTGKTAAYMLPTLERLLYRPLNNKAITRVLVLVPTRELGAQVYQVTKQLC 253 Query: 87 AKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKSLRPY-LKNVRFVVVD 145 T I + + G + +R P ++I TP L + +K+ + L ++ +++D Sbjct: 254 QFTTIDVGLAIGGLDVKAQEAVLRQNPDIVIATPGRL--IDHIKNTPSFTLDSIEVLILD 311 Query: 146 EVTELIDNKRGAQL--ILNLKRLSLIADFIRIGLSATVGNEEEVKEWLGVDEIVKPPLKK 203 E ++D Q+ I+N S + SAT+ + + + +D+ +K + Sbjct: 312 EADRMLDEYFAEQMKEIIN----SCCKTRQTMLFSATMSEQVKDLAAVSLDKPIKVFVNN 367 Query: 204 R----YKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEKHKRVLVFVNTRQFAE 259 + + F R R EDKE R + + RT H +VFV T++ A Sbjct: 368 NQQVAFNLRQEFIRIR-EDKEGD---REPILASLICRTF------HDHCMVFVQTKKQAH 417 Query: 260 VLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQ 319 L L G HG+L+++ R+E+ +K KE ++ LI T G+DI V VI Sbjct: 418 RLHILLGLLGVRAGELHGNLTQQQRLESLKKFKEEQIDVLIATDVAARGLDIVGVKTVIN 477 Query: 320 YMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSLII--AKRAIEGKL---ERI 374 ++ P I R GR+ R + +A E + II A+ I+ ++ E I Sbjct: 478 FVMPITTEHYIHRVGRTA-RAGRAGISVSLAGEKERKIVKDIIKNAESTIKNRIIPPEII 536 Query: 375 KPYENALDVLAHFIVGLLIEYQ 396 + Y N L L I +L E Q Sbjct: 537 EKYRNKLTSLEPEIQNILDEEQ 558 >gb|AAF59119.1| (AE003838) BcDNA:GM05306 gene product [Drosophila melanogaster] Length = 782 Score = 71.8 bits (173), Expect = 3e-11 Identities = 97/382 (25%), Positives = 165/382 (42%), Gaps = 32/382 (8%) Query: 30 GKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISC---LYIAPLKALNRDLLERLKWWE 86 G+ + A TG+GKT A +LP + +L L + L + P + L + + K Sbjct: 194 GRDICGCAATGTGKTAAYMLPTLERLLYRPLNNKAITRVLVLVPTRELGAQVYQVTKQLC 253 Query: 87 AKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKSLRPY-LKNVRFVVVD 145 T I + + G + +R P ++I TP L + +K+ + L ++ +++D Sbjct: 254 QFTTIDVGLAIGGLDVKAQEAVLRQNPDIVIATPGRL--IDHIKNTPSFTLDSIEVLILD 311 Query: 146 EVTELIDNKRGAQL--ILNLKRLSLIADFIRIGLSATVGNEEEVKEWLGVDEIVKPPLKK 203 E ++D Q+ I+N S + SAT+ + + + +D+ +K + Sbjct: 312 EADRMLDEYFAEQMKEIIN----SCCKTRQTMLFSATMSEQVKDLAAVSLDKPIKVFVNN 367 Query: 204 R----YKFKVLFPRPRPEDKELAELLRVDVEVAARLRTLWEIVEKHKRVLVFVNTRQFAE 259 + + F R R EDKE R + + RT H +VFV T++ A Sbjct: 368 NQQVAFNLRQEFIRIR-EDKEGD---REPILASLICRTF------HDHCMVFVQTKKQAH 417 Query: 260 VLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQ 319 L L G HG+L+++ R+E+ +K KE ++ LI T G+DI V VI Sbjct: 418 RLHILLGLLGVRAGELHGNLTQQQRLESLKKFKEEQIDVLIATDVAARGLDIVGVKTVIN 477 Query: 320 YMSPRQVNRLIQRAGRSKHRLLEVSEAYIIATGVEDYLQSLII--AKRAIEGKL---ERI 374 ++ P I R GR+ R + +A E + II A+ I+ ++ E I Sbjct: 478 FVMPITTEHYIHRVGRTA-RAGRAGISVSLAGEKERKIVKDIIKNAESTIKNRIIPPEII 536 Query: 375 KPYENALDVLAHFIVGLLIEYQ 396 + Y N L L I +L E Q Sbjct: 537 EKYRNKLTSLEPEIQNILDEEQ 558 >pir||T09159 RNA helicase prh75 - spinach >gi|1488647|emb|CAA68193.1| (X99937) RNA helicase [Spinacia oleracea] Length = 685 Score = 71.4 bits (172), Expect = 4e-11 Identities = 80/346 (23%), Positives = 148/346 (42%), Gaps = 30/346 (8%) Query: 3 ILLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP 62 +L+ K IK F +Q F + +G ++ A TG GKT A +LP++ S++ Sbjct: 121 VLISKGIKALFP----IQAMTFDNVIDGCDLVGRARTGQGKTLAFVLPIVESLVNGRTKD 176 Query: 63 I---------SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPP 113 + S L + P + L +L + + G+ +G + + + Sbjct: 177 LRRSGHGRLPSVLVLLPTRELATQVLADFQVYGGAVGLTACSVYGGAPFHSQISSLTRGV 236 Query: 114 HVLITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFI 173 +++ TP + LL L+ L ++ F V+DE E++ + L L ++ ++ Sbjct: 237 DIVVGTPGRVKDLLEKGVLK--LGSLLFRVLDEADEMLKMGFVDDVELILGKVDHVSKVQ 294 Query: 174 RIGLSATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA 233 + SAT+ + W V +I LK K L + + + + +A Sbjct: 295 TLLFSATLPS------W--VKQISTRFLKSAKKTVDLVSDQKMKASISVRHIVIPCSASA 346 Query: 234 RLRTLWEIVEKHK---RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERK 290 R + +I+ + R ++F T++ A LA L T +P+ HG + + R + Sbjct: 347 RPDLIPDIIRCYGSGGRSIIFTETKESASQLAGLL-TGARPL---HGDIQQTQREVTLKG 402 Query: 291 LKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 + GK L+ T+ G+DI +V +IQ PR V I R+GR+ Sbjct: 403 FRTGKFMTLVATNVAARGLDINDVQLIIQCEPPRDVEDYIHRSGRT 448 >pir||E81090 ATP-dependent RNA helicase, probable NMB1368 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7226614|gb|AAF41742.1| (AE002485) ATP-dependent RNA helicase, putative [Neisseria meningitidis MC58] Length = 462 Score = 71.0 bits (171), Expect = 5e-11 Identities = 75/346 (21%), Positives = 143/346 (40%), Gaps = 35/346 (10%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPP- 62 +L E + +Q +A EG+ ++ A TGSGKT A +LP + + K P Sbjct: 14 ILSAVSSEGYESPTPIQAQAIPFALEGRDIMASAQTGSGKTAAFLLPTLQKLTKRSEKPG 73 Query: 63 --ISCLYIAPLKALNRDL-------LERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPP 113 L + P + L + + ++W+ + + G + Y + + + P Sbjct: 74 KGPRALVLTPTRELAAQVEKNALAYAKNMRWFRT-----VSIVGGASFGY-QTRALSKPV 127 Query: 114 HVLITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFI 173 +++ TP L L+ +S + + + +++DE ++D + I D Sbjct: 128 DLIVATPGRLMDLM--QSGKVDFERLEVLILDEADRMLD-------------MGFIDDIE 172 Query: 174 RIGLSATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDK-ELAELLRVDVEVA 232 I + AT + + + D V +K K + R +D+ ++ E L ++ Sbjct: 173 TI-VEATPSDRQTLLFSATWDGAVGKLARKLTKDPEIIEVERVDDQGKIEEQLLYCDDMR 231 Query: 233 ARLRTLWEIVEKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERK 290 + R L I+ + ++F +T+ EV+A L G HG + + R Sbjct: 232 HKNRLLDHILRDANIDQCVIFTSTKAMTEVIADELYEKGFAANCLHGDMPQGWRNRTLMD 291 Query: 291 LKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 L++G+ K L+ T GID+ + VI Y P+Q + R GR+ Sbjct: 292 LRKGRCKILVATDVAARGIDVPTITHVINYDLPKQAEDYVHRIGRT 337 >dbj|BAB10010.1| (AB006697) RNA helicase-like protein [Arabidopsis thaliana] Length = 827 Score = 70.6 bits (170), Expect = 7e-11 Identities = 88/378 (23%), Positives = 153/378 (40%), Gaps = 41/378 (10%) Query: 7 KAIKEK-FRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDG------ 59 KAIK+ F + +Q I +GK VL A TG+GKT A +LP + +++K Sbjct: 372 KAIKDAGFETMTVVQEATLPIILQGKDVLAKAKTGTGKTVAFLLPAIEAVIKSPPASRDS 431 Query: 60 -LPPISCLYIAPLKAL-NRDLLERLKWWEAKTGIRIDVRHGDT---TQYRRAKQVRNPPH 114 PPI L + P + L ++ E + I + V G T T+ RR + NP Sbjct: 432 RQPPIIVLVVCPTRELASQAAAEANTLLKYHPSIGVQVVIGGTKLPTEQRRMQT--NPCQ 489 Query: 115 VLITTPETLPALL-TVKSLRPYLKNVRFVVVDEVTELIDN--KRGAQLILNL---KRLSL 168 +L+ TP L + L V+ +V+DE L+D +R + I+ +R + Sbjct: 490 ILVATPGRLKDHIENTSGFATRLMGVKVLVLDEADHLLDMGFRRDIERIIAAVPKQRQTF 549 Query: 169 IADFIRIGLSATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVD 228 + SATV E V +I LK+ ++F E + + + Sbjct: 550 L-------FSATVPEE--------VRQICHVALKRDHEFINCVQEGSGETHQKVTQMYMI 594 Query: 229 VEVAARLRTLWEIVEKH------KRVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKE 282 + L ++++H +V++F T ++A L V H + Sbjct: 595 ASLDRHFSLLHVLLKEHIADNVDYKVIIFCTTAMVTRLVADLLSQLSLNVREIHSRKPQS 654 Query: 283 ARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLE 342 R + ++ K L+ + G+D +V V+Q P + I R GR+ + E Sbjct: 655 YRTRVSDEFRKSKAIILVTSDVSARGVDYPDVSLVVQMGLPSDREQYIHRLGRTGRKGKE 714 Query: 343 VSEAYIIATGVEDYLQSL 360 ++A E ++ S+ Sbjct: 715 GEGVLLLAPWEEYFMSSV 732 >dbj|BAB05326.1| (AP001512) ATP-dependent DNA helicase [Bacillus halodurans] Length = 491 Score = 70.6 bits (170), Expect = 7e-11 Identities = 84/344 (24%), Positives = 157/344 (45%), Gaps = 46/344 (13%) Query: 20 QIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPISCLYIAPLKALNRDLL 79 Q E + + EG V + PTG+GK+ LP + +G+ L I+PL +L D + Sbjct: 20 QKEVIEALVEGNDVFAMLPTGTGKSICYQLPAR---ITEGVT----LVISPLLSLMEDQV 72 Query: 80 ERLK--WWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETLPALLTVKSLRPYLK 137 ++LK W+ + + G + R KQ+ + +L +PE + + K L+ Sbjct: 73 QQLKSNGWKDVAALSSFLSKG--AKERIIKQL-HLYKLLFLSPEMVQHPVVFKRLKQV-- 127 Query: 138 NVRFVVVDEVTELIDNKRGAQLILNLKRLSLIAD------FIRIGLSATVGNEEEVKEWL 191 V + VVDE + ++ G + RLS + + + +AT ++++ L Sbjct: 128 KVSYFVVDEAHCI--SQWGHDFRPDFLRLSDVKHQLGNPPCLALTATATPAVQQDILTQL 185 Query: 192 GVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVE----VAARLRTLWEIVEKHKR 247 +DE V ++ RP + + VE V +L + I+E+H Sbjct: 186 SIDEAVT----------IVHSVDRPN-------ISISVEQTPTVKDKLEVIRGIIERHSG 228 Query: 248 V-LVFVNTRQFAEVLAHRLK-TWGKPVEVHHGSLSKEARIEAERKLKEGKVKALICTSSM 305 +++ ++R ++E +A L K V +HG +S E RI +++ G++ + TS+ Sbjct: 229 AGIIYFSSRLWSEQIARELMLNVKKRVAFYHGGMSNEDRILIQQQFMAGELDLICSTSAF 288 Query: 306 ELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKHRLLEVSEAYII 349 +GI+ ++ VI Y P+Q+ +Q GR+ L S AY++ Sbjct: 289 GMGINKQDIRFVIHYHYPQQIASYVQEIGRAGRDGL-ASSAYVL 331 >sp|P35683|IF4A_ORYSA EUKARYOTIC INITIATION FACTOR 4A (EIF-4A) (EIF4A) >gi|542153|pir||S38358 translation initiation factor eIF-4A - rice >gi|303844|dbj|BAA02152.1| (D12627) eukaryotic initiation factor 4A [Oryza sativa] Length = 413 Score = 70.2 bits (169), Expect = 9e-11 Identities = 76/338 (22%), Positives = 146/338 (42%), Gaps = 24/338 (7%) Query: 4 LLKKAIKEKFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDGLPPI 63 LL+ F + + +Q +G V+ A +G+GKT ++ L + Sbjct: 52 LLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGILQQ-LDYAVVEC 110 Query: 64 SCLYIAPLKALNRDLLERLKWWEAKTGIRIDVRHGDTTQYRRAKQVRNPPHVLITTPETL 123 L +AP + L + + + ++ G+++ G T+ + + + HV++ TP + Sbjct: 111 QALVLAPTRELAQQIEKVMRALGDYLGVKVHACVGGTSVREDQRILASGVHVVVGTPGRV 170 Query: 124 PALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADFIRIGLSATVGN 183 +L +SLRP ++ V+DE E++ Q+ L+ I++G+ + Sbjct: 171 FDMLRRQSLRP--DYIKMFVLDEADEMLSRGFKDQIY---DIFQLLPSKIQVGVFSATMP 225 Query: 184 EEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKELAELLRVDVEVAA---RLRTLWE 240 E + EI + + K + V + ++ L + + V V +L TL + Sbjct: 226 PEAL-------EITRKFMNKPVRILV-----KRDELTLEGIKQFYVNVEKEEWKLDTLCD 273 Query: 241 IVEKHK--RVLVFVNTRQFAEVLAHRLKTWGKPVEVHHGSLSKEARIEAERKLKEGKVKA 298 + E + ++FVNTR+ + L +++ V HG + + R R+ + G + Sbjct: 274 LYETLAITQSVIFVNTRK-VDWLTDKMRGRDHTVSATHGDMDQNTRDIIMREFRSGSSRV 332 Query: 299 LICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRS 336 LI T + GID+ +V VI Y P Q + R GRS Sbjct: 333 LITTDLLARGIDVQQVSLVINYDLPTQPENYLHRIGRS 370 >gb|AAF48747.1| (AE003506) CG5800 gene product [Drosophila melanogaster] Length = 805 Score = 70.2 bits (169), Expect = 9e-11 Identities = 95/398 (23%), Positives = 172/398 (42%), Gaps = 43/398 (10%) Query: 6 KKAIKE-KFRELNRLQIEAFKRISEGKSVLIIAPTGSGKTEAAILPVMNSILKDG---LP 61 +KA+ E KF ++Q ++ +GK VL A TGSGKT A ++PV+ + + Sbjct: 84 QKALAESKFVHPTQVQRDSIGPALQGKDVLGAAITGSGKTLAFLIPVLEHLFMNKWSRTD 143 Query: 62 PISCLYIAPLKALNRDLLERLKWWEAKTGIRID-----VRHGDTTQYRRAKQVRNPPHVL 116 + + I+P + L + E LK K G D + G ++ R + + ++L Sbjct: 144 GVGAIIISPTRELAYQIFETLK----KVGKHHDFSAGLIIGGKNLKFERTRM--DQCNIL 197 Query: 117 ITTPETLPALLTVKSLRPYLKNVRFVVVDEVTELIDNKRGAQLILNLKRLSLIADF--IR 174 I TP L + L + +V+DE +D G Q LN S+I +F +R Sbjct: 198 ICTPGRLLQHMDENPLFN-TSTMEMLVLDEADRCLD--MGFQKTLN----SIIENFPPVR 250 Query: 175 IGLSATVGNEEEVKEWLGVDEIVKPPLKKRYKFKVLFPRPRPEDKE--------LAELLR 226 L + V++ ++ +K P+ Y P K+ + ELL+ Sbjct: 251 QTLLFSATQTNTVQDLARLN--LKDPVYVGYGGATPREEPSASTKKTPNTAVLAVPELLQ 308 Query: 227 ---VDVEVAARLRTLWEIVEKH--KRVLVFVNTRQFAEVLAH---RLKTWGKPVEVHHGS 278 V + + ++ LW ++ H ++++VFV + + A+ L +L+ G P+ +G+ Sbjct: 309 QSYVVLNLEDKITMLWSFIKNHLKQKIIVFVASCKQAKYLYEIFCKLRP-GSPLLALYGT 367 Query: 279 LSKEARIEAERKLKEGKVKALICTSSMELGIDIGEVDAVIQYMSPRQVNRLIQRAGRSKH 338 L ++ RI + T G+D V+ V+Q P V++ I RAGRS Sbjct: 368 LHQDRRIAIYEDFLRKSHVVMFSTDVASRGLDFPAVNWVVQLDCPEDVSQYIHRAGRSAR 427 Query: 339 RLLEVSEAYIIATGVEDYLQSLIIAKRAIEGKLERIKP 376 ++ E+Y+ S + + I+ + +I P Sbjct: 428 NKTRGECLLVLTPSEEEYMISALKEQLNIDIRCVQIDP 465 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.320 0.139 0.393 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 320657744 Number of Sequences: 2977 Number of extensions: 13653282 Number of successful extensions: 43983 Number of sequences better than 1.0e-10: 170 Number of HSP's better than 0.0 without gapping: 24 Number of HSP's successfully gapped in prelim test: 146 Number of HSP's that attempted gapping in prelim test: 43475 Number of HSP's gapped (non-prelim): 236 length of query: 912 length of database: 189,106,746 effective HSP length: 60 effective length of query: 852 effective length of database: 153,197,526 effective search space: 130524292152 effective search space used: 130524292152 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.8 bits) S2: 169 (70.2 bits)