BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1838 (PAB1838) DE:URACIL/XANTHINE PERMEASE (427 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||F75123 uracil/xanthine permease PAB1838 - Pyrococcus abyssi... 816 0.0 pir||A83278 probable transporter PA2938 [imported] - Pseudomonas... 260 2e-68 emb|CAB61314.1| (AL132997) putative permease [Streptomyces coeli... 254 1e-66 emb|CAB61316.1| (AL132997) putative permease [Streptomyces coeli... 252 5e-66 sp|O32139|YUNJ_BACSU PUTATIVE PURINE PERMEASE YUNJ >gi|7446782|p... 251 1e-65 sp|O32140|YUNK_BACSU PUTATIVE PURINE PERMEASE YUNK >gi|7446783|p... 244 1e-63 sp|Q46821|YGFU_ECOLI PUTATIVE PURINE PERMEASE YGFU 235 6e-61 pir||H65072 hypothetical protein b2888 - Escherichia coli (strai... 235 6e-61 sp|P42086|PBUX_BACSU XANTHINE PERMEASE >gi|1075933|pir||S51310 x... 235 1e-60 pir||C75614 probable xanthine permease - Deinococcus radiodurans... 230 2e-59 pir||G83457 probable transporter PA1507 [imported] - Pseudomonas... 230 3e-59 pir||A82042 xanthine/uracil permease family protein VC2712 [impo... 219 4e-56 sp|Q46815|YGFO_ECOLI PUTATIVE PURINE PERMEASE YGFO >gi|7449235|p... 215 1e-54 pir||B83601 probable transporter PA0352 [imported] - Pseudomonas... 215 1e-54 pir||D83625 probable transporter PA0166 [imported] - Pseudomonas... 215 1e-54 sp|P27432|YICE_ECOLI PUTATIVE PURINE PERMEASE YICE >gi|7449234|p... 208 1e-52 pir||E81141 xanthine/uracil permease family protein NMB0930 [imp... 208 1e-52 gb|AAF22490.1|AF098277_1 (AF098277) Na+/L-ascorbic acid transpor... 203 4e-51 gi|6755542 solute carrier family 23, (nucleobase transporters) m... 202 6e-51 pir||D75293 uracil permease - Deinococcus radiodurans (strain R1... 201 1e-50 pir||JC7182 Na+-dependent vitamin C (L-ascorbic acid) transporte... 201 1e-50 gb|AAF24759.1|AF170911_1 (AF170911) sodium-dependent vitamin C t... 201 1e-50 gi|8394381 sodium-coupled ascorbic acid transporter 1 [Rattus n... 201 1e-50 gi|5032233 sodium-dependent vitamin C transporter-1; yolk sac pe... 195 9e-49 gi|11421164 solute carrier family 23 (nucleobase transporters), ... 192 5e-48 emb|CAB89870.1| (AJ132624) uracil transporter [Lactococcus lactis] 192 5e-48 gi|4827020 solute carrier family 23 (nucleobase transporters), m... 192 8e-48 gb|AAC78807.1| (AF058320) yolk sac permease-like molecule 2 [Sus... 191 1e-47 gi|9055344 solute carrier family 23, (nucleobase transporters) m... 191 1e-47 gi|8394384 sodium-coupled ascorbic acid transporter 2 [Rattus no... 190 2e-47 gb|AAD11783.1| (AF092511) nucleobase transporter-like 1 protein ... 189 5e-47 pir||F72329 uracil permease - Thermotoga maritima (strain MSB8) ... 189 7e-47 pir||T20137 hypothetical protein C51E3.6 - Caenorhabditis elegan... 187 2e-46 pir||D82111 uracil permease VC2171 [imported] - Vibrio cholerae ... 186 5e-46 pir||E83066 uracil permease PA4647 [imported] - Pseudomonas aeru... 185 1e-45 dbj|BAB06259.1| (AP001515) uracil transporter (permease) [Bacill... 179 5e-44 sp|P50487|YCPX_CLOPE HYPOTHETICAL PROTEIN IN CPE 5'REGION >gi|18... 177 2e-43 sp|P41006|PYRP_BACCL URACIL PERMEASE (URACIL TRANSPORTER) >gi|48... 177 2e-43 dbj|BAB10858.1| (AB009053) permease 1 [Arabidopsis thaliana] 176 3e-43 sp|P45117|URAA_HAEIN PROBABLE URACIL PERMEASE (URACIL TRANSPORTE... 176 4e-43 gb|AAC73019.1| (AC005824) putative membrane transporter [Arabido... 176 5e-43 emb|CAB65186.1| (AJ012720) uracil permease [Lactobacillus planta... 175 9e-43 sp|P39766|PYRP_BACSU URACIL PERMEASE (URACIL TRANSPORTER) >gi|21... 171 2e-41 dbj|BAA94190.1| (AP000422) uracil transport protein [Escherichia... 170 3e-41 sp|P75892|YCDG_ECOLI HYPOTHETICAL 48.1 KD PROTEIN IN WRBA-PUTA I... 170 3e-41 dbj|BAA35773.1| (D90737) Uracil transport protein [Escherichia c... 170 3e-41 sp|P33780|URAA_ECOLI URACIL PERMEASE (URACIL TRANSPORTER) >gi|10... 169 7e-41 gb|AAD14479.1| (AC005966) Strong similarity to gi|3337350 F13P17... 168 1e-40 dbj|BAB08803.1| (AB024032) permease [Arabidopsis thaliana] 163 4e-39 pir||T24671 hypothetical protein T07G12.5 - Caenorhabditis elega... 162 5e-39 gb|AAF76447.1|AC015445_14 (AC015445) Identical to permease homol... 162 9e-39 gb|AAD30433.1|AF118561_1 (AF118561) sodium-coupled ascorbic acid... 161 1e-38 gb|AAD26910.1|AC007233_2 (AC007233) putative membrane transporte... 161 2e-38 gb|AAC12928.1| (AF044978) putative uracil permease [Enterococcus... 161 2e-38 pir||T12309 permease 1 - common ice plant >gi|3202038|gb|AAC1940... 159 4e-38 gb|AAB17501.2| (U43034) permease 1 [Zea mays] 159 8e-38 pir||T33745 hypothetical protein R11E3.2 - Caenorhabditis elegan... 158 1e-37 pir||T12313 permease 1 - common ice plant >gi|3202040|gb|AAC1940... 155 7e-37 pir||D81844 uracil permease NMA1528 [imported] - Neisseria menin... 155 9e-37 pir||T00984 permease homolog T9J22.18 - Arabidopsis thaliana >gi... 155 1e-36 pir||T02307 permease homolog F13P17.3 - Arabidopsis thaliana >gi... 153 3e-36 pir||B81096 uracil permease NMB1315 [imported] - Neisseria menin... 152 7e-36 gb|AAF54519.1| (AE003686) CG6293 gene product [Drosophila melano... 148 9e-35 pir||T05632 hypothetical protein F20D10.170 - Arabidopsis thalia... 148 1e-34 gb|AAB60909.1| (AC001229) Similar to Zea mays permease 1 (gb|U43... 141 1e-32 sp|Q07307|UAPA_EMENI URIC ACID-XANTHINE PERMEASE (UAPA TRANSPORT... 140 2e-32 pir||T02719 permease 1 - maize 140 2e-32 dbj|BAA13244.1| (D87075) similar to Mouse yolk sac permease-like... 139 4e-32 emb|CAB76872.1| (AL159139) putative uracyl permease [Streptomyce... 139 6e-32 pir||T24675 hypothetical protein T07G12.2 - Caenorhabditis elega... 138 1e-31 sp|P48777|UAPC_EMENI PURINE PERMEASE >gi|1362518|pir||A56382 pur... 138 2e-31 gb|AAD39576.1|AC007067_16 (AC007067) T10O24.16 [Arabidopsis thal... 136 4e-31 pir||I40857 hypothetical protein 1 - Clostridium perfringens 132 9e-30 sp|P39618|YWDJ_BACSU PUTATIVE PURINE PERMEASE YWDJ >gi|2126970|p... 127 3e-28 gb|AAF60824.1| (AC024838) contains similarity to Pfam families P... 123 3e-27 pir||A48878 uric acid/xanthine transport protein - Emericella ni... 118 1e-25 pir||T24677 hypothetical protein T07G12.4 - Caenorhabditis elega... 108 1e-22 pir||H64782 probable membrane protein b0513 - Escherichia coli >... 103 3e-21 sp|P77328|YBBY_ECOLI PUTATIVE PURINE PERMEASE YBBY >gi|2735239|g... 103 3e-21 gb|AAA92292.1| (U25739) YSPL-1 form 1 [Mus musculus] 96 6e-19 gb|AAA92293.1| (U25739) YSPL-1 form 2 [Mus musculus] 83 7e-15 gb|AAF34271.1| (M14339) unknown [Streptococcus pneumoniae] 82 1e-14 gb|AAB41234.1| (U83501) permease homolog [Arabidopsis thaliana] 74 3e-12 >pir||F75123 uracil/xanthine permease PAB1838 - Pyrococcus abyssi (strain Orsay) >gi|5458214|emb|CAB49703.1| (AJ248285) URACIL/XANTHINE PERMEASE [Pyrococcus abyssi] Length = 427 Score = 816 bits (2085), Expect = 0.0 Identities = 427/427 (100%), Positives = 427/427 (100%) Query: 1 MGPGVLVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLL 60 MGPGVLVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLL Sbjct: 1 MGPGVLVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLL 60 Query: 61 AMGIATLLQTTIGSRYPIVQGSSFAFIPGLISIGKSLGMAATEGALIVGGIIEALIGGTG 120 AMGIATLLQTTIGSRYPIVQGSSFAFIPGLISIGKSLGMAATEGALIVGGIIEALIGGTG Sbjct: 61 AMGIATLLQTTIGSRYPIVQGSSFAFIPGLISIGKSLGMAATEGALIVGGIIEALIGGTG 120 Query: 121 IVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITTV 180 IVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITTV Sbjct: 121 IVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITTV 180 Query: 181 YVALKAKGPIRAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLTA 240 YVALKAKGPIRAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLTA Sbjct: 181 YVALKAKGPIRAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLTA 240 Query: 241 IVTLLFAFMVSIIESVGDYHAISAIAEAPITNKHINRGIMSEGIACSIAGILGACGTTSY 300 IVTLLFAFMVSIIESVGDYHAISAIAEAPITNKHINRGIMSEGIACSIAGILGACGTTSY Sbjct: 241 IVTLLFAFMVSIIESVGDYHAISAIAEAPITNKHINRGIMSEGIACSIAGILGACGTTSY 300 Query: 301 SENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVT 360 SENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVT Sbjct: 301 SENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVT 360 Query: 361 GLRLIKDKVELNDRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAITAI 420 GLRLIKDKVELNDRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAITAI Sbjct: 361 GLRLIKDKVELNDRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAITAI 420 Query: 421 VLDQLLR 427 VLDQLLR Sbjct: 421 VLDQLLR 427 >pir||A83278 probable transporter PA2938 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9949034|gb|AAG06326.1|AE004720_2 (AE004720) probable transporter [Pseudomonas aeruginosa] Length = 485 Score = 260 bits (657), Expect = 2e-68 Identities = 149/412 (36%), Positives = 244/412 (59%), Gaps = 16/412 (3%) Query: 22 GLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTT----IGSRYP 77 GLQHVL M+G V VPL++G A GL+ +I ++I A L A G+ATLLQT G + P Sbjct: 4 GLQHVLTMYGGIVAVPLILGQAAGLAPGDIGLLIAASLFAGGLATLLQTLGVPFFGCQLP 63 Query: 78 IVQGSSFAFIPGLISI---GKSLGMAATEGALIVGGIIEALIGGTGIVGKVKRLFTPLVT 134 +VQG SFA + +++I G S G+ A GA++ +I LI T I ++ + F PLVT Sbjct: 64 LVQGVSFAGVATMVAIIGSGGSGGIPAVLGAVMAASLIGLLI--TPIFSRITKFFPPLVT 121 Query: 135 GVTIMLIGFSLADVAVKYFF--NFYADPSGSSIPRATI-VALVTFITTVYVALKAKGPIR 191 G+ I IG +L VA ++ N +A GS A I +A +T + + ++ I Sbjct: 122 GIVITTIGLTLMPVAARWAMGGNSHAPDFGSM---ANIGLAAITLVIVLLLSKLGSASIS 178 Query: 192 AMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVS 251 + ++ ++G +++V LG+A+F V E PLV+ P PF +G+P F + AI+++ MV+ Sbjct: 179 RLSILLAMVIGTVIAVFLGMADFSKVTEGPLVAFPTPFHFGMPTFQVAAIISMCIVIMVT 238 Query: 252 IIESVGDYHAISAIAEAPITNKHINRGIMSEGIACSIAGILGACGTTSYSENIGLVALTK 311 ++E+ D A+ I + + ++ + G+ ++ + +A I G+ +++++N+GLVA+T Sbjct: 239 LVETSADILAVGEIIDTKVDSRRLGNGLRADMFSSMLAPIFGSFTQSAFAQNVGLVAVTG 298 Query: 312 VASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVEL 371 + SRYVV GG+ LV+L L P ++A++P VLGG I L+G ++ +G+R + Sbjct: 299 IKSRYVVATGGLFLVILGLLPVMGRVIAAVPTAVLGGAGIVLFGTVAASGIRTLSKVDYR 358 Query: 372 NDRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAITAIVLD 423 N+ N +I+ATS+ G+ P P F HFP A+I SG++ AI AI+L+ Sbjct: 359 NNMNLIIVATSIGFGM-IPIAAPTFYDHFPSWFATIFHSGISSSAIMAILLN 409 >emb|CAB61314.1| (AL132997) putative permease [Streptomyces coelicolor A3(2)] Length = 471 Score = 254 bits (642), Expect = 1e-66 Identities = 148/426 (34%), Positives = 240/426 (55%), Gaps = 16/426 (3%) Query: 9 VDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLL 68 VDEK+ P + + LQH+ AM+ VT PL++G A GL E + +I A LL G+ATLL Sbjct: 31 VDEKLHPSRLVPAALQHIAAMYAGVVTPPLIIGQACGLDIEGRTRLIAASLLIAGVATLL 90 Query: 69 QTT-----IGSRYPIVQGSSFAFIPGLISI----GKSLGMAATEGALIVGGIIEALIGGT 119 QT +G+R P V +S A I +++I K + A GA++V G+ +G Sbjct: 91 QTLGVKGFVGNRLPFVNAASSAGIAPILAIVETNAKGSQLPAVYGAVMVAGVFCLAVGP- 149 Query: 120 GIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITT 179 G++ R F PLVTGV I LIG +L V V + D + + +AL F Sbjct: 150 -FFGRLLRFFPPLVTGVVITLIGVTLMPVPVGWAQG--GDKTAADFGSMRNLALAAFTLA 206 Query: 180 VYVALK--AKGPIRAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFN 237 V + ++ KG ++ + ++ G L+G L ++P G+A+F ++ P+ +LP PF +G PEF Sbjct: 207 VILVIQRFGKGFVKQVALLFGLLIGTLAAIPFGMADFGALRSAPVAALPTPFAFGAPEFQ 266 Query: 238 LTAIVTLLFAFMVSIIESVGDYHAISAIAEAPITNKHINRGIMSEGIACSIAGILGACGT 297 AI++L +V + ES A+ I + + I RG+ ++G+A + + G T Sbjct: 267 PAAILSLCIVMLVLMTESSAGMLALGEICDRRADARVITRGLRTDGLATLVGPVFGGFPT 326 Query: 298 TSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMI 357 +++++N+G+V+LT+V SRYVV + G L+VL FP +++ +P PVLGG I L+G I Sbjct: 327 SAFAQNVGVVSLTRVRSRYVVAVAGATLLVLGAFPVLGAVVSLVPMPVLGGAGIVLFGSI 386 Query: 358 SVTGLRLIKDKVELNDRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAI 417 +V+G+R + + + N +++A +L G+ P P F A FP ++L SG++ GAI Sbjct: 387 AVSGIRTLSEAGLDDSSNIILVAVALGAGI-IPLAAPTFYAEFPAWAQTVLGSGISAGAI 445 Query: 418 TAIVLD 423 A+ L+ Sbjct: 446 VAVALN 451 >emb|CAB61316.1| (AL132997) putative permease [Streptomyces coelicolor A3(2)] Length = 462 Score = 252 bits (637), Expect = 5e-66 Identities = 147/426 (34%), Positives = 235/426 (54%), Gaps = 16/426 (3%) Query: 9 VDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLL 68 VDEK+ P K GLQHV AM+ V PL+VG A+GLS E++ + A L G+AT L Sbjct: 6 VDEKLPPLKMATTGLQHVAAMYAGVVAPPLIVGAAIGLSATELTFLTGACLFTAGLATFL 65 Query: 69 QTT----IGSRYPIVQGSSFAFIPGLISI-----GKSLGMAATEGALIVGGIIEALIGGT 119 QT IG+R P V G +FA + + ++ KS + GA+IV G++ + Sbjct: 66 QTLGIWKIGARLPFVNGVTFAGVAPMTAVVASTDDKSDALPIIFGAVIVAGLLGFV--AA 123 Query: 120 GIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVAL--VTFI 177 K R F P+VTG I LIG SL VA + P+ AT + L +T Sbjct: 124 PFFSKAIRFFPPVVTGTVITLIGISLLPVAFGWAQG--PSPTADDFGSATNLGLAGITLA 181 Query: 178 TTVYVALKAKGPIRAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFN 237 +++ +G ++ + V+ G + G LV++P G+ +F V + +V P PF +G P+F Sbjct: 182 IVLFLRRFTRGFVKQIAVLLGLVAGTLVAIPFGVTDFGPVADADVVGFPTPFHFGAPQFQ 241 Query: 238 LTAIVTLLFAFMVSIIESVGDYHAISAIAEAPITNKHINRGIMSEGIACSIAGILGACGT 297 + AI+++ +VS+ ES D A+ I + P K I G+ ++ + +++ + Sbjct: 242 IAAIISMCVVMVVSMTESTADMLALGEIVDRPADEKTIAAGLRADTLGSALSPVFNGFMC 301 Query: 298 TSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMI 357 +++++NIGLVA+TK+ SRYVV +GG LV++ L P A ++A +P PVLGG + L+G + Sbjct: 302 SAFAQNIGLVAMTKIRSRYVVAVGGGFLVLMGLCPMAASLIAVVPRPVLGGAGVVLFGSV 361 Query: 358 SVTGLRLIKDKVELNDRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAI 417 + +G++ + D N LI+A SL VG+ P P+F FP IL+SG++ G + Sbjct: 362 AASGIQTLVRASLDKDNNVLIVAVSLAVGI-IPIAAPEFYHSFPENARIILDSGISTGCV 420 Query: 418 TAIVLD 423 A++L+ Sbjct: 421 AAVLLN 426 >sp|O32139|YUNJ_BACSU PUTATIVE PURINE PERMEASE YUNJ >gi|7446782|pir||E70016 purine permease homolog yunJ - Bacillus subtilis >gi|2635740|emb|CAB15233.1| (Z99120) similar to purine permease [Bacillus subtilis] Length = 449 Score = 251 bits (634), Expect = 1e-65 Identities = 146/416 (35%), Positives = 231/416 (55%), Gaps = 13/416 (3%) Query: 17 KAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTT----I 72 K L LQHVLAM+ + VPL+VG A+ ++ E++S ++ LL G+ATLLQT I Sbjct: 7 KVFTLSLQHVLAMYAGAILVPLLVGRALNVTTEQLSYLLAIDLLTCGVATLLQTLRGTYI 66 Query: 73 GSRYPIVQGSSFAFIPGLISIGKSLGMAATEGALIVGGIIEALIGGTGIVGKVKRLFTPL 132 G P++ GSSF + +I+IG + G+ A G++I G+ L GK+ LF P+ Sbjct: 67 GIGLPVMLGSSFVAVTPMIAIGSNYGIHAIYGSIIAAGVFIFLFAR--FFGKLTVLFPPV 124 Query: 133 VTGVTIMLIGFSLADVAVKYF-----FNFYADPSGSSIPRATIVALVTFITTVYVALKAK 187 VTG + LIG SL VK N A+P S+ ++++ + + + K Sbjct: 125 VTGTVVTLIGLSLVPTGVKNMAGGEKINGSANPEYGSLENL-LLSVGVLVLILVLNRFLK 183 Query: 188 GPIRAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLTAIVTLLFA 247 G R + V+ G G + +G +F V E P +P+PF +G P F + I+T+L Sbjct: 184 GFARTLSVLIGIAAGTAAAAIMGKVSFSSVTEAPFFQIPKPFYFGAPAFEIGPILTMLIV 243 Query: 248 FMVSIIESVGDYHAISAIAEAPITNKHINRGIMSEGIACSIAGILGACGTTSYSENIGLV 307 +V I+ES G ++AI I P+T+K + +G +EGIA I G+ A ++++N GL+ Sbjct: 244 GIVIIVESTGVFYAIGKICGRPLTDKDLVKGYRAEGIAILIGGLFNAFPYNTFAQNAGLL 303 Query: 308 ALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKD 367 LTKV +R +V G ILV L L PK A + +++PA VLGG T+ ++GM+ +G++++ Sbjct: 304 QLTKVKTRNIVVTAGCILVCLGLIPKIAALASAVPAAVLGGATVVMFGMVIASGVKMLST 363 Query: 368 KVELNDRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAITAIVLD 423 N + L +A S+ +G+GA P F A FP + ++ G G++TAI L+ Sbjct: 364 ADLKNQYHLLTIACSIALGIGASTAPGIF-AEFPAPIRILVSDGTITGSLTAIFLN 418 >sp|O32140|YUNK_BACSU PUTATIVE PURINE PERMEASE YUNK >gi|7446783|pir||F70016 purine permease homolog yunK - Bacillus subtilis >gi|2635741|emb|CAB15234.1| (Z99120) similar to purine permease [Bacillus subtilis] Length = 430 Score = 244 bits (617), Expect = 1e-63 Identities = 149/412 (36%), Positives = 236/412 (57%), Gaps = 16/412 (3%) Query: 19 ILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTT----IGS 74 ++LGLQH+LAM+ + VPL+VG A+GL+ +++ +I L G ATLLQ G Sbjct: 11 MMLGLQHMLAMYAGAILVPLIVGAAIGLNAGQLTYLIAIDLFMCGAATLLQLWRNRYFGI 70 Query: 75 RYPIVQGSSFAFIPGLISIGKSLGMAATEGALIVGGIIEALIGGTGIVGKVKRLFTPLVT 134 P+V G +F + +ISIG + G+ A GA+I G+I L G GK+ R F P+VT Sbjct: 71 GLPVVLGCTFTAVGPMISIGSTYGVPAIYGAIIAAGLIVVL--AAGFFGKLVRFFPPVVT 128 Query: 135 GVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITTVYVALKA---KGPIR 191 G +M+IG SL A+ N A GS + L+ F T ++ L KG IR Sbjct: 129 GSVVMIIGISLIPTAM----NNLAGGEGSKEFGSLDNVLLGFGVTAFILLLFYFFKGFIR 184 Query: 192 AMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVS 251 ++ ++ G + G + +G +F V E + +P F +G P F L A+VT+L +VS Sbjct: 185 SIAILLGLIAGTAAAYFMGKVDFSEVLEASWLHVPSLFYFGPPTFELPAVVTMLLVAIVS 244 Query: 252 IIESVGDYHAISAIAEAPITNKHINRGIMSEGIACSIAGILGACGTTSYSENIGLVALTK 311 ++ES G Y A++ I ++ K + +G +EG+A + G+ A T++S+N+G+V L+K Sbjct: 245 LVESTGVYFALADITNRRLSEKDLEKGYRAEGLAILLGGLFNAFPYTAFSQNVGIVQLSK 304 Query: 312 VASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVEL 371 + S V+ I GIILV + L PK A + +P PVLGG I ++GM+ G++++ V+L Sbjct: 305 MKSVNVIAITGIILVAIGLVPKAAALTTVIPTPVLGGAMIVMFGMVISYGIKML-SSVDL 363 Query: 372 NDR-NTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAITAIVL 422 + + N LI+A+S+ +GLGA +P F + + + SG+ IG++TAI L Sbjct: 364 DSQGNLLIIASSVSLGLGATTVPALF-SSLSGAASVLAGSGIVIGSLTAIAL 414 >sp|Q46821|YGFU_ECOLI PUTATIVE PURINE PERMEASE YGFU Length = 482 Score = 235 bits (594), Expect = 6e-61 Identities = 142/425 (33%), Positives = 240/425 (56%), Gaps = 14/425 (3%) Query: 8 KVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATL 67 +VD + P K I+LGLQHVL M+ V VPL++G +GLSKE I+++I + L GI TL Sbjct: 20 EVDRILSPGKLIILGLQHVLVMYAGAVAVPLMIGDRLGLSKEAIAMLISSDLFCCGIVTL 79 Query: 68 LQTT-----IGSRYPIVQGSSFAFIPGLISIGKS--LGMAATEGALIVGGIIEALIGGTG 120 LQ +G R P++ +FA + +I+IG + +G+ GA I G I L+ Sbjct: 80 LQCIGIGRFMGIRLPVIMSVTFAAVTPMIAIGMNPDIGLLGIFGATIAAGFITTLLAP-- 137 Query: 121 IVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPS-GSSIPRATIVALVTFITT 179 ++G++ LF PLVTGV I IG S+ V + + +P G+ + A++ FI Sbjct: 138 LIGRLMPLFPPLVTGVVITSIGLSIIQVGIDWAAGGKGNPQYGNPVYLGISFAVLIFI-- 195 Query: 180 VYVALKAKGPIRAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLT 239 + + AKG + + V+ G + G+L+S + N + + ++ P +G+P F+ Sbjct: 196 LLITRYAKGFMSNVAVLLGIVFGFLLSWMMNEVNLSGLHDASWFAIVTPMSFGMPIFDPV 255 Query: 240 AIVTLLFAFMVSIIESVGDYHAISAIAEAPITNKHINRGIMSEGIACSIAGILGACGTTS 299 +I+T+ ++ IES+G + A+ I +++ I RG+ +G+ I G + TS Sbjct: 256 SILTMTAVLIIVFIESMGMFLALGEIVGRKLSSHDIIRGLRVDGVGTMIGGTFNSFPHTS 315 Query: 300 YSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISV 359 +S+N+GLV++T+V SR+V GIIL++ + PK A ++AS+P VLGG + ++GM+ Sbjct: 316 FSQNVGLVSVTRVHSRWVCISSGIILILFGMVPKMAVLVASIPQFVLGGAGLVMFGMVLA 375 Query: 360 TGLRLI-KDKVELNDRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAIT 418 TG+R++ + N N I+A SL VG+ P L F + P ++ +L SG+ + ++ Sbjct: 376 TGIRILSRCNYTTNRYNLYIVAISLGVGM-TPTLSHDFFSKLPAVLQPLLHSGIMLATLS 434 Query: 419 AIVLD 423 A+VL+ Sbjct: 435 AVVLN 439 >pir||H65072 hypothetical protein b2888 - Escherichia coli (strain K-12) >gi|887838|gb|AAA83069.1| (U28375) ORF_o505 [Escherichia coli] >gi|1789254|gb|AAC75926.1| (AE000372) putative permease [Escherichia coli K12] Length = 505 Score = 235 bits (594), Expect = 6e-61 Identities = 142/425 (33%), Positives = 240/425 (56%), Gaps = 14/425 (3%) Query: 8 KVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATL 67 +VD + P K I+LGLQHVL M+ V VPL++G +GLSKE I+++I + L GI TL Sbjct: 43 EVDRILSPGKLIILGLQHVLVMYAGAVAVPLMIGDRLGLSKEAIAMLISSDLFCCGIVTL 102 Query: 68 LQTT-----IGSRYPIVQGSSFAFIPGLISIGKS--LGMAATEGALIVGGIIEALIGGTG 120 LQ +G R P++ +FA + +I+IG + +G+ GA I G I L+ Sbjct: 103 LQCIGIGRFMGIRLPVIMSVTFAAVTPMIAIGMNPDIGLLGIFGATIAAGFITTLLAP-- 160 Query: 121 IVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPS-GSSIPRATIVALVTFITT 179 ++G++ LF PLVTGV I IG S+ V + + +P G+ + A++ FI Sbjct: 161 LIGRLMPLFPPLVTGVVITSIGLSIIQVGIDWAAGGKGNPQYGNPVYLGISFAVLIFI-- 218 Query: 180 VYVALKAKGPIRAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLT 239 + + AKG + + V+ G + G+L+S + N + + ++ P +G+P F+ Sbjct: 219 LLITRYAKGFMSNVAVLLGIVFGFLLSWMMNEVNLSGLHDASWFAIVTPMSFGMPIFDPV 278 Query: 240 AIVTLLFAFMVSIIESVGDYHAISAIAEAPITNKHINRGIMSEGIACSIAGILGACGTTS 299 +I+T+ ++ IES+G + A+ I +++ I RG+ +G+ I G + TS Sbjct: 279 SILTMTAVLIIVFIESMGMFLALGEIVGRKLSSHDIIRGLRVDGVGTMIGGTFNSFPHTS 338 Query: 300 YSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISV 359 +S+N+GLV++T+V SR+V GIIL++ + PK A ++AS+P VLGG + ++GM+ Sbjct: 339 FSQNVGLVSVTRVHSRWVCISSGIILILFGMVPKMAVLVASIPQFVLGGAGLVMFGMVLA 398 Query: 360 TGLRLI-KDKVELNDRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAIT 418 TG+R++ + N N I+A SL VG+ P L F + P ++ +L SG+ + ++ Sbjct: 399 TGIRILSRCNYTTNRYNLYIVAISLGVGM-TPTLSHDFFSKLPAVLQPLLHSGIMLATLS 457 Query: 419 AIVLD 423 A+VL+ Sbjct: 458 AVVLN 462 >sp|P42086|PBUX_BACSU XANTHINE PERMEASE >gi|1075933|pir||S51310 xanthine transport protein pbuX - Bacillus subtilis >gi|633170|emb|CAA58759.1| (X83878) xanthine permease [Bacillus subtilis] >gi|1256618|gb|AAA96612.1| (L77246) transport protein [Bacillus subtilis] >gi|2634625|emb|CAB14123.1| (Z99115) xanthine permease [Bacillus subtilis] Length = 438 Score = 235 bits (592), Expect = 1e-60 Identities = 131/413 (31%), Positives = 227/413 (54%), Gaps = 12/413 (2%) Query: 17 KAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTT----I 72 K + LG+QHVLAM+ + VPL+VG A+GL+ E+++ ++ + G+ATLLQ Sbjct: 7 KTLSLGIQHVLAMYAGAIVVPLIVGKAMGLTVEQLTYLVSIDIFMCGVATLLQVWSNRFF 66 Query: 73 GSRYPIVQGSSFAFIPGLISIGKSLGMAATEGALIVGGIIEALIGGTGIVGKVKRLFTPL 132 G P+V G +F + +I+IG G++ G++I GI+ LI + GK+ F P+ Sbjct: 67 GIGLPVVLGCTFTAVSPMIAIGSEYGVSTVYGSIIASGILVILI--SFFFGKLVSFFPPV 124 Query: 133 VTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITTVYVALK--AKGPI 190 VTG + +IG +L VA+ N + + +AL + ++ V L KG I Sbjct: 125 VTGSVVTIIGITLMPVAMN---NMAGGEGSADFGDLSNLALAFTVLSIIVLLYRFTKGFI 181 Query: 191 RAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMV 250 +++ ++ G L+G ++ +G F V + +V + +PF +G P F+ I+T+ +V Sbjct: 182 KSVSILIGILIGTFIAYFMGKVQFDNVSDAAVVQMIQPFYFGAPSFHAAPIITMSIVAIV 241 Query: 251 SIIESVGDYHAISAIAEAPITNKHINRGIMSEGIACSIAGILGACGTTSYSENIGLVALT 310 S++ES G Y A+ + +T +++G +EG+A + GI A T++S+N+GLV LT Sbjct: 242 SLVESTGVYFALGDLTNRRLTEIDLSKGYRAEGLAVLLGGIFNAFPYTAFSQNVGLVQLT 301 Query: 311 KVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVE 370 + V+ + G+IL+ LFPK A +P+ VLGG +A++GM+ G++++ Sbjct: 302 GIKKNAVIVVTGVILMAFGLFPKIAAFTTIIPSAVLGGAMVAMFGMVIAYGIKMLSRIDF 361 Query: 371 LNDRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAITAIVLD 423 N LI+A S+ +GLG +P F P + + +G+ G+ TA+VL+ Sbjct: 362 AKQENLLIVACSVGLGLGVTVVPDIF-KQLPSALTLLTTNGIVAGSFTAVVLN 413 >pir||C75614 probable xanthine permease - Deinococcus radiodurans (strain R1) >gi|6460489|gb|AAF12195.1|AE001862_21 (AE001862) xanthine permease, putative [Deinococcus radiodurans] Length = 480 Score = 230 bits (581), Expect = 2e-59 Identities = 129/422 (30%), Positives = 234/422 (54%), Gaps = 10/422 (2%) Query: 9 VDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLL 68 VDE + ++ GLQHV++M+ V VPL++ A+GL + ++ A G+ATL+ Sbjct: 34 VDEVPAAQNLLVFGLQHVMSMYAGIVAVPLILAGALGLDATTAARIVSASFFMCGLATLV 93 Query: 69 QTT----IGSRYPIVQGSSFAFIPGLISIGKSLGMAATEGALIVGGIIEALIGGTGIVGK 124 QT G++ PIVQG++FA + +I +GK G+ GA+I GG+ L+ + Sbjct: 94 QTLGVGPFGAKLPIVQGTTFAAVGTMILVGKEFGLPGIYGAVIAGGLFTILLAP--YFSR 151 Query: 125 VKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITTVYVAL 184 + R F P+V+G I +IG SL VA + +P+ S P +A +T + + ++ Sbjct: 152 LLRFFPPVVSGTVITMIGISLLPVAFNWAGGGVGNPNFGS-PGNLGLAAITLLIVLLISR 210 Query: 185 KAKGPIRAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLTAIVTL 244 +G + + V+ G ++G +++ G N + V P +G P ++L I+++ Sbjct: 211 FGRGYLGRIAVLLGLVIGSVIAALFGQVNGAPISSAAWVGFTPPLAFGAPTWHLVPILSM 270 Query: 245 LFAFMVSIIESVGDYHAISAIAEAPITNKHINRGIMSEGIACSIAGILGACGTTSYSENI 304 L +V ++E+ D AI I + + + G+ ++G++ ++ G+ + T++++N+ Sbjct: 271 LLVMLVVMVETTADLLAIGEITGKKVGPREVAAGLRADGLSTAVGGLFNSFPFTAFAQNV 330 Query: 305 GLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLRL 364 GLV T + SR+VV G+IL+++ FPK + ++AS+P PVLGG + L+ ++V+G++ Sbjct: 331 GLVRFTGIKSRFVVAAAGVILLLMGFFPKLSALVASIPLPVLGGAGLVLFASVAVSGIQT 390 Query: 365 IKDKVELND-RNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAITAIVLD 423 + KV+L+D RN +++ SL +GL P P AH P L SG+ ++ AI+L+ Sbjct: 391 LA-KVDLSDTRNLTVVSVSLALGL-IPSTVPGLYAHLPAQAQLFLGSGITAASLCAILLN 448 Query: 424 QL 425 L Sbjct: 449 IL 450 >pir||G83457 probable transporter PA1507 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9947463|gb|AAG04896.1|AE004579_8 (AE004579) probable transporter [Pseudomonas aeruginosa] Length = 455 Score = 230 bits (580), Expect = 3e-59 Identities = 143/423 (33%), Positives = 234/423 (54%), Gaps = 10/423 (2%) Query: 9 VDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLL 68 VD+++ + +L+G QHVL M+G V VPL+VG A GLS+EEI+ +I A LL GIATL+ Sbjct: 14 VDQRLPLTQLLLVGFQHVLLMYGGAVAVPLIVGQAAGLSREEIAFLINADLLVAGIATLV 73 Query: 69 QTT----IGSRYPIVQGSSFAFIPGLISIGKSLGMAATE--GALIVGGIIEALIGGTGIV 122 Q+ +G R P++ G+SFA + ++++ G+ T GA I G LI + Sbjct: 74 QSLGIGPMGIRMPVMMGASFAAVGSMVAMAGMPGVGITGIFGATIAAGFFGMLIAP--FM 131 Query: 123 GKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITTVYV 182 ++ R F PLVTG I IG L VA+ + S+ + +LV T + + Sbjct: 132 SRIVRFFPPLVTGTVITSIGMCLFPVAINWAGGGKGAEDFGSLHFLFLSSLV-LCTILLI 190 Query: 183 ALKAKGPIRAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLTAIV 242 +G + V+ G +GY ++ +G+ + + E P + P +G P F+L I+ Sbjct: 191 NRFMRGFWVNISVLMGMGLGYAIAGGMGMVDLGGLAERPWFDIVTPLHFGAPTFDLAPIL 250 Query: 243 TLLFAFMVSIIESVGDYHAISAIAEAPITNKHINRGIMSEGIACSIAGILGACGTTSYSE 302 ++ ++ +ES G + A+ I IT + RG++ + A AG L +S+++ Sbjct: 251 SMCLVVVIIFVESTGMFLALGKITGREITPTELRRGLLCDAGASFFAGFLNTFTHSSFAQ 310 Query: 303 NIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGL 362 NIGLV +T V SRYV L++LS+ PK A ++AS+P VLGG IA++GM++ +G+ Sbjct: 311 NIGLVQMTGVRSRYVTVAAAGFLILLSMLPKAAFLVASIPPAVLGGAGIAMFGMVAASGI 370 Query: 363 RLIKDKVELNDRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAITAIVL 422 +++ + + RN L++A S+ +G+ P + P F A P + I SG+A+ AI A+VL Sbjct: 371 QILHEANITDRRNQLLVAVSIGMGM-VPVVRPDFFARLPVWMEPITHSGIAMTAIWAVVL 429 Query: 423 DQL 425 + L Sbjct: 430 NLL 432 >pir||A82042 xanthine/uracil permease family protein VC2712 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9657309|gb|AAF95852.1| (AE004337) xanthine/uracil permease family protein [Vibrio cholerae] Length = 480 Score = 219 bits (553), Expect = 4e-56 Identities = 137/429 (31%), Positives = 239/429 (54%), Gaps = 24/429 (5%) Query: 17 KAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTT----I 72 + + LQH+LAMF A +T L++ ++G+ ++ + +I L A G+++ +Q I Sbjct: 35 QTLFAALQHLLAMFVAVITPSLIICQSLGVPADQTNTIISMSLFASGLSSFIQIRTFGPI 94 Query: 73 GSRYPIVQGSSFAFIPGLISIGKSLG---------MAATEGALIVGGIIEALIGGTGIVG 123 GS +QG+SF F+ +I G +L MAA G ++V E L+ + ++ Sbjct: 95 GSGLLSIQGTSFNFLGPIIGAGLALKAGGADIETMMAAIFGTILVASSAEILL--SRVLQ 152 Query: 124 KVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITTVYVA 183 +R+ TPLV+G+ + LIG +L V + YA + S +AL + + V Sbjct: 153 FAQRIITPLVSGIVVTLIGLTLVQVGLISMGGGYAAMADGSFGSLDKLALAGTVLAIIVL 212 Query: 184 L-KAKGP-IRAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLTAI 241 L +A P +R ++ LVGY+++ +G+ N + E ++LP P +G+ F+ + Sbjct: 213 LNRAHNPYVRVASIVIAMLVGYVMAYLMGMVNTDNLAETQFIALPIPMQYGLG-FDWSLF 271 Query: 242 VTLLFAFMVSIIESVGDYHAISAIA----EAPITNKHINRGIMSEGIACSIAGILGACGT 297 + L+ F+++ +E++GD A S ++ + P+ K I G++++G+ ++A + + Sbjct: 272 IPLVLIFLITALEAIGDITATSEVSGEPVKGPVYMKRIKGGVLADGLNSALAAVFNSFPN 331 Query: 298 TSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMI 357 +++S+N G++ LT VASRYV +LV+L LFP A + +P PVLGG TI ++G I Sbjct: 332 STFSQNNGVILLTGVASRYVGYFIAGMLVLLGLFPGVASFVQLIPEPVLGGATIVMFGTI 391 Query: 358 SVTGLRLIKDKVELNDRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAI 417 + G+R+I +V+L+ R LI+A S +GLG Q P+ L P + ++ SG+A G I Sbjct: 392 AAAGVRII-SRVDLDRRAILIMALSFSMGLGIAQ-KPEILQFMPEFIKNLFSSGVAAGGI 449 Query: 418 TAIVLDQLL 426 TAIVL+ LL Sbjct: 450 TAIVLNLLL 458 >sp|Q46815|YGFO_ECOLI PUTATIVE PURINE PERMEASE YGFO >gi|7449235|pir||B65072 hypothetical protein b2882 - Escherichia coli (strain K-12) >gi|887832|gb|AAA83063.1| (U28375) ORF_o485 [Escherichia coli] >gi|1789248|gb|AAC75920.1| (AE000372) putative transport protein [Escherichia coli K12] Length = 485 Score = 215 bits (541), Expect = 1e-54 Identities = 130/444 (29%), Positives = 246/444 (55%), Gaps = 24/444 (5%) Query: 2 GPGVLVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLA 61 G ++ +++++ +A++ + H+LA+F VT L+VG A+ LS E + ++ ++A Sbjct: 27 GSDLIFELEDRPPFHQALVGAITHLLAIFVPMVTPALIVGAALQLSAETTAYLVSMAMIA 86 Query: 62 MGIATLLQTT----IGSRYPIVQGSSFAFIPGLISIGKSLG---------MAATEGALIV 108 GI T LQ +GS +Q +F+F+ +I++G S+ M++ G V Sbjct: 87 SGIGTWLQVNRYGIVGSGLLSIQSVNFSFVTVMIALGSSMKSDGFHEELIMSSLLGVSFV 146 Query: 109 GGIIEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRA 168 G + ++G + I+ ++R+ TP V+G+ +++IG SL V + F +A S + Sbjct: 147 GAFL--VVGSSFILPYLRRVITPTVSGIVVLMIGLSLIKVGIIDFGGGFAAKSSGTFGNY 204 Query: 169 TIVALVTFITTVYVALKA-KGPIRAMPVIA-GALVGYLVSVPLGLANFQLVKELPLVSLP 226 + + + V + + P+ M IA G VGY+ S+ LG+ +F ++ LPL+++P Sbjct: 205 EHLGVGLLVLIVVIGFNCCRSPLLRMGGIAIGLCVGYIASLCLGMVDFSSMRNLPLITIP 264 Query: 227 RPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEAPITNKH----INRGIMSE 282 PF +G F+ + + +++S++E+VGD A + ++ PI + + G++++ Sbjct: 265 HPFKYGF-SFSFHQFLVVGTIYLLSVLEAVGDITATAMVSRRPIQGEEYQSRLKGGVLAD 323 Query: 283 GIACSIAGILGACGTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMP 342 G+ IA +G+ T++++N G++ +T VASRYV + ++LV+L LFP G ++P Sbjct: 324 GLVSVIASAVGSLPLTTFAQNNGVIQMTGVASRYVGRTIAVMLVILGLFPMIGGFFTTIP 383 Query: 343 APVLGGLTIALYGMISVTGLRLIKDKVELNDRNTLILATSLIVGLGAPQLPPKFLAHFPR 402 + VLGG ++ MI++ G+R+I L R TLI+ATSL +GLG P+ P Sbjct: 384 SAVLGGAMTLMFSMIAIAGIRIIITN-GLKRRETLIVATSLGLGLGV-SYDPEIFKILPA 441 Query: 403 IVASILESGMAIGAITAIVLDQLL 426 + ++E+ + G +TAI+L+ +L Sbjct: 442 SIYVLVENPICAGGLTAILLNIIL 465 >pir||B83601 probable transporter PA0352 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9946202|gb|AAG03741.1|AE004473_3 (AE004473) probable transporter [Pseudomonas aeruginosa] Length = 461 Score = 215 bits (541), Expect = 1e-54 Identities = 138/437 (31%), Positives = 242/437 (54%), Gaps = 24/437 (5%) Query: 9 VDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLL 68 +D++ A+L LQH+LA+ VT L++ A+G+S + ++++ L+ GIAT + Sbjct: 20 LDDRPSAPIALLAALQHLLAIIVPIVTPGLLICQALGVSPRDTNLIVSMSLVISGIATFV 79 Query: 69 QTT----IGSRYPIVQGSSFAFIPGLISIGKSLG---------MAATEGALIVGGIIEAL 115 Q G+ IVQG+SF F+ LI+ G + MAA G +I G +E Sbjct: 80 QCKRFGPFGAGLLIVQGTSFNFVGPLIAGGALMVKQGTPVESVMAAIFGVVIAGSFVE-- 137 Query: 116 IGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVT 175 +G + I+ VKRL TPLVTG+ +++IG +L V + ++ S + + L Sbjct: 138 MGISRILPFVKRLITPLVTGIVVLMIGLTLIKVGLISMGGGFSAMSNGTFANGENLLLSG 197 Query: 176 FITTVYVALKAKGPI--RAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGI 233 + + V L + R+ ++ VGY ++ LG +F + + L +P P +G+ Sbjct: 198 VVLGIIVVLNRIPVVWMRSCAIVIALAVGYALAGYLGRLDFTGMHQAELFQVPTPLHFGL 257 Query: 234 PEFNLTAIVTLLFAFMVSIIESVGDYHAISAIA----EAPITNKHINRGIMSEGIACSIA 289 +F+ + +L ++V+ +E++GD A S ++ E P+ + I G++ G +A Sbjct: 258 -DFSWPLFIPMLVIYLVTSLEAIGDVTATSKVSKQPVEGPLWMQRIKGGVLVNGANSFLA 316 Query: 290 GILGACGTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGL 349 GI ++ +++N G++ LT VASRYV +LV+L LFP AG++ ++P PVLGG Sbjct: 317 GIFNTFPSSVFAQNNGVIQLTGVASRYVGLWIAAMLVLLGLFPSVAGVIQAVPEPVLGGA 376 Query: 350 TIALYGMISVTGLRLIKDKVELNDRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILE 409 + ++G ++ +G+ ++ ++L+ R LI+A SL +GLG Q+ P+FLAH P + ++LE Sbjct: 377 AMVMFGAVAASGINILAG-IQLDRRALLIIAVSLALGLGVSQV-PEFLAHMPAALRNVLE 434 Query: 410 SGMAIGAITAIVLDQLL 426 SG+A G I A++L+ L Sbjct: 435 SGVATGGICALLLNWFL 451 >pir||D83625 probable transporter PA0166 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9945998|gb|AAG03556.1|AE004454_8 (AE004454) probable transporter [Pseudomonas aeruginosa] Length = 468 Score = 215 bits (541), Expect = 1e-54 Identities = 143/437 (32%), Positives = 239/437 (53%), Gaps = 28/437 (6%) Query: 9 VDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLL 68 +D++ P A L LQHVLA F VT PLV+G+ +GL E + +I L+ G TL+ Sbjct: 15 LDDRPRPLPAFLAALQHVLASFVGIVTPPLVIGSLLGLG-EHLPYLISMALMVSGAGTLI 73 Query: 69 QTT----IGSRYPIVQGSSFAFIPGLISIG---KSLG------MAATEGALIVGGIIEAL 115 Q IG+ +QG+SFAF+ +++ G K G +A G G ++ + Sbjct: 74 QARRPFGIGAGMICLQGTSFAFLGAVLAAGMLVKQRGGGPEEILAMIFGVCFFGAFVQIV 133 Query: 116 IGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVT 175 + + +G ++R+ TPLVTG+ I LIG SL V + + + ALV Sbjct: 134 L--SRFLGHLRRVITPLVTGIVITLIGVSLIKVGITDLGGGAGATDFGAPANLALGALV- 190 Query: 176 FITTVYVALKAKGP-IRAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIP 234 + ++ + +++ P +R ++ G +G L + GL + + ELPLVSLP+PF +G Sbjct: 191 -LLSIVLLNRSRLPWLRLAAIVIGLALGTLAAWATGLFVPRALPELPLVSLPQPFRFGFA 249 Query: 235 EFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEAPITN----KHINRGIMSEGIACSIAG 290 F+ A + + +++S IE+VGD A ++ P+ + + G++ +G++C +A Sbjct: 250 -FDWMAFLPVALIYLISSIETVGDLTANCMLSRQPLEGPAYLQRLRGGVLGDGVSCLLAA 308 Query: 291 ILGACGTTSYSENIGLVALTKVASRYV-VQIGGIILVVLSLFPKFAGILASMPAPVLGGL 349 A T++++N G++ LT VASR+V + IGG++L L LFP IL +P PVLGG Sbjct: 309 TFSAFPNTTFAQNNGVIQLTGVASRHVGIYIGGVLLA-LGLFPWVGAILQQIPKPVLGGA 367 Query: 350 TIALYGMISVTGLRLIKDKVELNDRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILE 409 T+ ++G ++ G+R++ + ++ R+ LI+A S VGLG P L P +V ++ + Sbjct: 368 TLVMFGSVAAAGIRIL-GQTAMDRRSVLIIAASFGVGLGV-AAQPTLLDQMPAVVKTLFD 425 Query: 410 SGMAIGAITAIVLDQLL 426 S + G ITAI+L+ LL Sbjct: 426 SAITSGGITAILLNLLL 442 >sp|P27432|YICE_ECOLI PUTATIVE PURINE PERMEASE YICE >gi|7449234|pir||H65166 hypothetical 48.9 kD protein in gltS 3'region - Escherichia coli (strain K-12) >gi|290504|gb|AAA62007.1| (L10328) o463 [Escherichia coli] >gi|1790087|gb|AAC76678.1| (AE000443) putative transport protein [Escherichia coli K12] Length = 463 Score = 208 bits (523), Expect = 1e-52 Identities = 136/441 (30%), Positives = 243/441 (54%), Gaps = 29/441 (6%) Query: 5 VLVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGI 64 ++ +++++ + + QH+LAMF A +T L++ A+GL ++ +I L A G+ Sbjct: 22 LIYRLEDRPPLPQTLFAACQHLLAMFVAVITPALLICQALGLPAQDTQHIISMSLFASGV 81 Query: 65 ATLLQTT----IGSRYPIVQGSSFAFIPGLISIGKSLG---------MAATEGALIVGGI 111 A+++Q +GS +QG+SF F+ LI G +L MAA G L++ Sbjct: 82 ASIIQIKAWGPVGSGLLSIQGTSFNFVAPLIMGGTALKTGGADVPTMMAALFGTLMLASC 141 Query: 112 IEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSI--PRAT 169 E +I + ++ +R+ TPLV+GV +M+IG SL V + YA S ++ P+ Sbjct: 142 TEMVI--SRVLHLARRIITPLVSGVVVMIIGLSLIQVGLTSIGGGYAAMSDNTFGAPKNL 199 Query: 170 IVALVTFITTVYVALKAKGPIRAMPVIAGALVGYLVSVPLGL---ANFQLVKELPLVSLP 226 ++A V + + + +R ++ GY ++ +G+ +N + +EL +V P Sbjct: 200 LLAGVVLALIILLNRQRNPYLRVASLVIAMAAGYALAWFMGMLPESNEPMTQELIMVPTP 259 Query: 227 RPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEAPITN----KHINRGIMSE 282 + GI E++L ++ L+ FM++ +E++GD A S ++E P++ K + G+++ Sbjct: 260 LYYGLGI-EWSL--LLPLMLVFMITSLETIGDITATSDVSEQPVSGPLYMKRLKGGVLAN 316 Query: 283 GIACSIAGILGACGTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMP 342 G+ ++ + + + +N G++ LT VASRYV + ++L+VL LFP +G + +P Sbjct: 317 GLNSFVSAVFNTFPNSCFGQNNGVIQLTGVASRYVGFVVALMLIVLGLFPAVSGFVQHIP 376 Query: 343 APVLGGLTIALYGMISVTGLRLIKDKVELNDRNTLILATSLIVGLGAPQLPPKFLAHFPR 402 PVLGG T+ ++G I+ +G+R++ + LN R LI+A SL VGLG Q P L P Sbjct: 377 EPVLGGATLVMFGTIAASGVRIV-SREPLNRRAILIIALSLAVGLGVSQ-QPLILQFAPE 434 Query: 403 IVASILESGMAIGAITAIVLD 423 + ++L SG+A G ITAIVL+ Sbjct: 435 WLKNLLSSGIAAGGITAIVLN 455 >pir||E81141 xanthine/uracil permease family protein NMB0930 [imported] - Neisseria meningitidis (group B strain MD58, group A strain Z2491) >gi|7226168|gb|AAF41337.1| (AE002444) xanthine/uracil permease family protein [Neisseria meningitidis MC58] >gi|7379819|emb|CAB84387.1| (AL162755) putative transmembrane transport protein [Neisseria meningitidis Z2491] Length = 463 Score = 208 bits (523), Expect = 1e-52 Identities = 135/447 (30%), Positives = 244/447 (54%), Gaps = 36/447 (8%) Query: 3 PGVLVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAM 62 P ++ ++++ A+L + H+LA+F +T L+VG A+ L E + ++ ++A Sbjct: 12 PDLVYGLEDRPPFGNALLSAVTHLLAIFVPMITPALIVGGALELPVEMTAYLVSMAMVAS 71 Query: 63 GIATLLQTT----IGSRYPIVQGSSFAFIPGLISIGKSLGMAATEGALIVGGIIEALIG- 117 G+ T LQ +GS +Q +F+F+ +I++G + EG L +I L+G Sbjct: 72 GVGTYLQVNRFGPVGSGMLSIQSVNFSFVTVMIALGAGM----KEGGLTKDAMISTLLGV 127 Query: 118 ----------GTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYF---FNFYADPSGSS 164 ++ +K++ TP V+GV +MLIG SL V + F F AD + S Sbjct: 128 SFVGAFLVCFSAWLLPYLKKVITPTVSGVVVMLIGLSLVHVGITDFGGGFGAKADGTFGS 187 Query: 165 IPRATIVALVTFITTVYVALKAKGPIRAMPVIA-GALVGYLVSVPLGLANFQLVKELPLV 223 + + +LV I V+ +K P+ M IA G + GY+V++ LG +F ++ LPLV Sbjct: 188 MENLGLASLVLLIVLVFNCMK--NPLLRMSGIAVGLIAGYIVALFLGKVDFSALQNLPLV 245 Query: 224 SLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEAPITN----KHINRGI 279 +LP PF +G F+ A + F++S+ E+VGD A + +++ PI K + G+ Sbjct: 246 TLPVPFKYGFA-FDWHAFIVAGAIFLLSVFEAVGDLTATAMVSDQPIEGEEYTKRLRGGV 304 Query: 280 MSEGIACSIAGILGACGTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILA 339 +++G+ IA LG+ T++++N G++ +T VASR+V + +ILV+L LFP Sbjct: 305 LADGLVSVIATALGSLPLTTFAQNNGVIQMTGVASRHVGKYIAVILVLLGLFPVVGRAFT 364 Query: 340 SMPAPVLGGLTIALYGMISVTGLRLIKDKVELNDRNTLILATSLIVGLGAPQLPPKFLAH 399 ++P+PVLGG + ++G+I++ G+R++ + R +I ATS+ +GLG P F Sbjct: 365 TIPSPVLGGAMVLMFGLIAIAGVRILVSH-GIRRREAVIAATSVGLGLGVAFEPEVF--- 420 Query: 400 FPRIVASILESGMAIGAITAIVLDQLL 426 + + + ++ ++ G ITA++L+ +L Sbjct: 421 --KNLPVLFQNSISAGGITAVLLNLVL 445 >gb|AAF22490.1|AF098277_1 (AF098277) Na+/L-ascorbic acid transporter 1; SVCT1 [Homo sapiens] Length = 598 Score = 203 bits (510), Expect = 4e-51 Identities = 150/490 (30%), Positives = 236/490 (47%), Gaps = 79/490 (16%) Query: 5 VLVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTA--VGLSKEEISIMIQAVLLAM 62 +L K+++ ILLG QH L F T+ VP ++ A VG + +S +I + + Sbjct: 31 MLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGHDQHMVSQLIGTIFTCV 90 Query: 63 GIATLLQTTIGSRYPIVQGSSFAFI---PGLISIGK-------------SLGMAAT---- 102 GI TL+QTT+G R P+ Q S+FAF+ ++++ + SL + + Sbjct: 91 GITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEIYGNWSLPLNTSHIWH 150 Query: 103 ------EGALIVGGIIEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNF 156 +GA++V ++E +IG G+ G + PL T+ LIG S+ A Sbjct: 151 PRIRDVQGAIMVSSVVEVVIGLLGLPGALLNYIGPLTVTPTVSLIGLSVFQAA------- 203 Query: 157 YADPSGS--SIPRATIVALV---------TFITTVY-----VALKAKGPIRAMPVIAGAL 200 D +GS I +I+ ++ TF+ VY + L + P++ + Sbjct: 204 -GDRAGSHWGISACSILLIILFSQYLRNLTFLLPVYRWGKGLTLLRIQIFKMFPIMLAIM 262 Query: 201 VGYLVSVPLGL------------------ANFQLVKELPLVSLPRPFPWGIPEFNLTAIV 242 +L+ L L A ++ P + +P P WG+P A++ Sbjct: 263 TVWLLCYVLTLTEVLPTDPKAYGFQARTDARGDIMAIAPWIRIPYPCQWGLPTVTAAAVL 322 Query: 243 TLLFAFMVSIIESVGDYHAISAIAEAPITNKH-INRGIMSEGIACSIAGILGAC-GTTSY 300 + A + IIES+GDY+A + +A AP H INRGI +EGI C IAG+LG G+TS Sbjct: 323 GMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSS 382 Query: 301 SENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVT 360 S NIG++ +TKV SR VVQ G I++VL KF + AS+P P+LGG+ L+GMI+ Sbjct: 383 SPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKFTALFASLPDPILGGMFCTLFGMITAV 442 Query: 361 GLRLIKDKVELNDRNTLILATSLIVGLGAPQ-LPPK------FLAHFPRIVASILESGMA 413 GL ++ + RN +L S+ GL P L P + +I+ +L + M Sbjct: 443 GLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLSPNPGAINTGILEVDQILIVLLTTEMF 502 Query: 414 IGAITAIVLD 423 +G A +LD Sbjct: 503 VGGCLAFILD 512 >gi|6755542 solute carrier family 23, (nucleobase transporters) member 2; solute carrier family 23, (nucleobase transporters) member 1; DNA segment, Chr 18, University of California at Los Angeles 2 [Mus musculus] >gi|3789787|gb|AAC78805.1| (AF058318) yolk sac permease-like molecule 3 [Mus musculus] Length = 605 Score = 202 bits (509), Expect = 6e-51 Identities = 152/490 (31%), Positives = 234/490 (47%), Gaps = 79/490 (16%) Query: 5 VLVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTA--VGLSKEEISIMIQAVLLAM 62 +L K+++ ILLG QH L F T+ VP ++ A VG + +S +I + + Sbjct: 38 MLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGRDQHMVSQLIGTIFTCV 97 Query: 63 GIATLLQTTIGSRYPIVQGSSFAFIPGLISI----------------GKSLGMAAT---- 102 GI TL+QTT+G R P+ Q S+FAF+ SI S+ + + Sbjct: 98 GITTLIQTTVGIRLPLFQASAFAFLVPAKSILALERWKCPSEEEIYGNWSMPLNTSHIWH 157 Query: 103 ------EGALIVGGIIEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNF 156 +GA++V ++E +IG G+ G + PL T+ LIG Y F Sbjct: 158 PRIREVQGAIMVSSMVEVVIGLMGLPGALLSYIGPLTVTPTVSLIGL--------YVFQA 209 Query: 157 YADPSGS--SIPRATIVALV---------TFITTVY-----VALKAKGPIRAMPVIAGAL 200 D +GS I +I+ +V TF+ VY + L + P++ + Sbjct: 210 AGDRAGSHWGISACSILLIVLFSQYLRNLTFLLPVYRWGKGLTLFRVQIFKMFPIVLAIM 269 Query: 201 VGYLVSVPLGLAN----------FQ--------LVKELPLVSLPRPFPWGIPEFNLTAIV 242 +L+ L L + FQ ++ P + +P P WG+P + A++ Sbjct: 270 TVWLLCYVLTLTDVLPADPTVYGFQARTDARGDIMAISPWIRIPYPCQWGLPTVTVAAVL 329 Query: 243 TLLFAFMVSIIESVGDYHAISAIAEAPITNKH-INRGIMSEGIACSIAGILGAC-GTTSY 300 + A + IIES+GDY+A + +A AP H INRGI +EGI C IAG+LG G+TS Sbjct: 330 GMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSS 389 Query: 301 SENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVT 360 S NIG++ +TKV SR VVQ G I+++L KF + AS+P P+LGG+ L+GMI+ Sbjct: 390 SPNIGVLGITKVGSRRVVQYGAGIMLILGAIGKFTALFASLPDPILGGMFCTLFGMITAV 449 Query: 361 GLRLIKDKVELNDRNTLILATSLIVGLGAPQL----PPKFLAHFP---RIVASILESGMA 413 GL ++ + RN +L S+ GL P P P +I+ +L + M Sbjct: 450 GLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLDSNPGAINTGIPEVDQILTVLLTTEMF 509 Query: 414 IGAITAIVLD 423 +G A +LD Sbjct: 510 VGGCLAFILD 519 >pir||D75293 uracil permease - Deinococcus radiodurans (strain R1) >gi|6460088|gb|AAF11827.1|AE002060_6 (AE002060) uracil permease [Deinococcus radiodurans] Length = 496 Score = 201 bits (506), Expect = 1e-50 Identities = 139/424 (32%), Positives = 229/424 (53%), Gaps = 46/424 (10%) Query: 15 PRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLL-QTTIG 73 P++ ++LGLQH +AMFG+TV VP++VG + ++ L G+ATL+ Sbjct: 88 PQRRVVLGLQHSIAMFGSTVLVPILVGLSPSVA-----------LFGAGVATLIFHLLTR 136 Query: 74 SRYPIVQGSSFAFIPGLISIGKSLGMAATEGALIVGGIIEALIGG-TGIVG--KVKRLFT 130 + PI GSSFAFI + K +G AA G LI G++ L G + G ++ R+F Sbjct: 137 GQVPIFLGSSFAFIAPTALVIKEMGPAAAAGGLIAAGLMYVLFSGLVKLFGTERLLRVFP 196 Query: 131 PLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITTVYVALKAKGPI 190 P+VTG I++IG L+ VAV + +ALVT + + ++ +G Sbjct: 197 PVVTGPVIIVIGLGLSSVAVDQAKTNWG------------LALVTLLAAIIASIYGRGLF 244 Query: 191 RAMPVIAGALVGYLVSVPLGLANFQLVKEL---PLVSLPRPFPWGIPEFNLTAIVTLLFA 247 R +P++ G + GYLV++ G + + ++ PL+ LP P+ P + A+ + Sbjct: 245 RMIPILIGVVTGYLVALATGQVGAKALADIAAAPLLGLP---PFHGPALDWRAVAIIAPV 301 Query: 248 FMVSIIESVGDYHAIS-AIAEAPITNKHINRGIMSEGIACSIAGILGACGTTSYSENIGL 306 +V+ IE VGD + + + N ++R ++++GIA + ++G T+Y+EN G+ Sbjct: 302 AIVTFIEHVGDVVVNGRVVGKNFLANPGLSRTLLADGIANMSSAVMGGPAATTYAENTGV 361 Query: 307 VALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLR-LI 365 +ALT+V V+QIG + ++ PK A +L +P VLGG++I L+GMI+ G+R L Sbjct: 362 LALTRVYDPRVIQIGAVFAILFGCSPKLAAVLQGLPQGVLGGVSILLFGMIASVGIRTLA 421 Query: 366 KDKVEL-NDRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASI-LE-SGMAIGAITAIVL 422 + +V+ + RN +I++ L++GLG A FP VA LE GMA+ A+ IV Sbjct: 422 EAQVDFAHSRNLIIVSLILVLGLGG--------ASFPLNVAGTKLELHGMALAALVGIVA 473 Query: 423 DQLL 426 + LL Sbjct: 474 NLLL 477 >pir||JC7182 Na+-dependent vitamin C (L-ascorbic acid) transporter SVCT1 - human >gi|6048255|emb|CAB58119.1| (AJ269477) sodium-dependent vitamin C transporter [Homo sapiens] >gi|11125153|emb|CAC15384.1| (AJ250807) sodium-dependent vitamin C transporter [Homo sapiens] Length = 598 Score = 201 bits (506), Expect = 1e-50 Identities = 149/490 (30%), Positives = 236/490 (47%), Gaps = 79/490 (16%) Query: 5 VLVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTA--VGLSKEEISIMIQAVLLAM 62 +L K+++ ILLG QH L F T+ VP ++ A VG + +S +I + + Sbjct: 31 MLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGHDQHMVSQLIGTIFTCV 90 Query: 63 GIATLLQTTIGSRYPIVQGSSFAFI---PGLISIGK-------------SLGMAAT---- 102 GI TL+QTT+G R P+ Q S+FAF+ ++++ + SL + + Sbjct: 91 GITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEIYGNWSLPLNTSHIWH 150 Query: 103 ------EGALIVGGIIEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNF 156 +GA++V ++E +IG G+ G + PL T+ LIG S+ A Sbjct: 151 PRIREVQGAIMVSSVVEVVIGLLGLPGALLNYIGPLTVTPTVSLIGLSVFQAA------- 203 Query: 157 YADPSGS--SIPRATIVALV---------TFITTVY-----VALKAKGPIRAMPVIAGAL 200 D +GS I +I+ ++ TF+ VY + L + P++ + Sbjct: 204 -GDRAGSHWGISACSILLIILFSQYLRNLTFLLPVYRWGKGLTLLRIQIFKMFPIMLAIM 262 Query: 201 VGYLVSVPLGLAN----------FQ--------LVKELPLVSLPRPFPWGIPEFNLTAIV 242 +L+ L L + FQ ++ P + +P P WG+P A++ Sbjct: 263 TVWLLCYVLTLTDVLPTDPKAYGFQARTDARGDIMAIAPWIRIPYPCQWGLPTVTAAAVL 322 Query: 243 TLLFAFMVSIIESVGDYHAISAIAEAPITNKH-INRGIMSEGIACSIAGILGAC-GTTSY 300 + A + IIES+GDY+A + +A AP H INRGI +EGI C IAG+LG G+TS Sbjct: 323 GMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSS 382 Query: 301 SENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVT 360 S NIG++ +TKV SR VVQ G I++VL KF + AS+P P+LGG+ L+GMI+ Sbjct: 383 SPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKFTALFASLPDPILGGMFCTLFGMITAV 442 Query: 361 GLRLIKDKVELNDRNTLILATSLIVGLGAPQLPPK-------FLAHFPRIVASILESGMA 413 GL ++ + RN +L S+ GL P + +I+ +L + M Sbjct: 443 GLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLESNPGAINTGILEVDQILIVLLTTEMF 502 Query: 414 IGAITAIVLD 423 +G A +LD Sbjct: 503 VGGCLAFILD 512 >gb|AAF24759.1|AF170911_1 (AF170911) sodium-dependent vitamin C transporter 1 [Homo sapiens] Length = 598 Score = 201 bits (506), Expect = 1e-50 Identities = 149/490 (30%), Positives = 236/490 (47%), Gaps = 79/490 (16%) Query: 5 VLVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTA--VGLSKEEISIMIQAVLLAM 62 +L K+++ ILLG QH L F T+ VP ++ A VG + +S +I + + Sbjct: 31 MLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGHDQHMVSQLIGTIFTCV 90 Query: 63 GIATLLQTTIGSRYPIVQGSSFAFI---PGLISIGK-------------SLGMAAT---- 102 GI TL+QTT+G R P+ Q S+FAF+ ++++ + SL + + Sbjct: 91 GITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEIYGNWSLPLNTSHIWH 150 Query: 103 ------EGALIVGGIIEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNF 156 +GA++V ++E +IG G+ G + PL T+ LIG S+ A Sbjct: 151 PRIREVQGAIMVSSVVEVVIGLLGLPGALLNYIGPLTVTPTVSLIGLSVFQAA------- 203 Query: 157 YADPSGS--SIPRATIVALV---------TFITTVY-----VALKAKGPIRAMPVIAGAL 200 D +GS I +I+ ++ TF+ VY + L + P++ + Sbjct: 204 -GDRAGSHWGISACSILLIILFSQYLRNLTFLLPVYRWGKGLTLLRIQIFKMFPIMLAIM 262 Query: 201 VGYLVSVPLGLAN----------FQ--------LVKELPLVSLPRPFPWGIPEFNLTAIV 242 +L+ L L + FQ ++ P + +P P WG+P A++ Sbjct: 263 TVWLLCYVLTLTDVLPTDPKAYGFQARTDARGDIMAIAPWIRIPYPCQWGLPTVTAAAVL 322 Query: 243 TLLFAFMVSIIESVGDYHAISAIAEAPITNKH-INRGIMSEGIACSIAGILGAC-GTTSY 300 + A + IIES+GDY+A + +A AP H INRGI +EGI C IAG+LG G+TS Sbjct: 323 GMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSS 382 Query: 301 SENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVT 360 S NIG++ +TKV SR VVQ G I++VL KF + AS+P P+LGG+ L+GMI+ Sbjct: 383 SPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKFTALFASLPDPILGGMFCTLFGMITAV 442 Query: 361 GLRLIKDKVELNDRNTLILATSLIVGLGAPQLPPK-------FLAHFPRIVASILESGMA 413 GL ++ + RN +L S+ GL P + +I+ +L + M Sbjct: 443 GLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLESNPGAINTGILEVDQILIVLLTTEMF 502 Query: 414 IGAITAIVLD 423 +G A +LD Sbjct: 503 VGGCLAFILD 512 >gi|8394381 sodium-coupled ascorbic acid transporter 1 [Rattus norvegicus] >gi|4836172|gb|AAD30367.1|AF080452_1 (AF080452) sodium-coupled ascorbic acid transporter SVCT1 [Rattus norvegicus] Length = 604 Score = 201 bits (506), Expect = 1e-50 Identities = 152/490 (31%), Positives = 233/490 (47%), Gaps = 79/490 (16%) Query: 5 VLVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTA--VGLSKEEISIMIQAVLLAM 62 +L K+++ ILLG QH L F T+ VP ++ A VG + IS +I + + Sbjct: 38 MLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGRDQHMISQLIGTIFTCV 97 Query: 63 GIATLLQTTIGSRYPIVQGSSFAFI--------------PGLISIGKSLGMAAT------ 102 GI TL+QTT+G R P+ Q S+FAF+ P I + M Sbjct: 98 GITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEIYGNWSMPLNTSHIWH 157 Query: 103 ------EGALIVGGIIEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNF 156 +GA++V ++E +IG G+ G + PL T+ LIG S+ A Sbjct: 158 PRIREVQGAIMVSSVVEVVIGLLGLPGALLSYIGPLTVTPTVSLIGLSVFQAA------- 210 Query: 157 YADPSGS--SIPRATIVALV---------TFITTVY-----VALKAKGPIRAMPVIAGAL 200 D +GS I +I+ +V TF+ VY + L + P++ + Sbjct: 211 -GDRAGSHWGISACSILLIVLFSQYLRNLTFLLPVYRWGKGLTLFRIQIFKMFPIVLAIM 269 Query: 201 VGYLVSVPLGLAN----------FQ--------LVKELPLVSLPRPFPWGIPEFNLTAIV 242 +L+ L L + FQ ++ P + +P P WG+P + A++ Sbjct: 270 TVWLLCYVLTLTDVLPADPTVYGFQARTDARGDIMAISPWIRIPYPCQWGLPTVTVAAVL 329 Query: 243 TLLFAFMVSIIESVGDYHAISAIAEAPITNKH-INRGIMSEGIACSIAGILGAC-GTTSY 300 + A + IIES+GDY+A + +A AP H INRGI +EG+ C IAG+LG G+TS Sbjct: 330 GMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGVCCIIAGLLGTGNGSTSS 389 Query: 301 SENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVT 360 S NIG++ +TKV SR VVQ G I+++L KF + AS+P P+LGG+ L+GMI+ Sbjct: 390 SPNIGVLGITKVGSRRVVQYGAGIMLILGAIGKFTALFASLPDPILGGMFCTLFGMITAV 449 Query: 361 GLRLIKDKVELNDRNTLILATSLIVGLGAPQL----PPKFLAHFP---RIVASILESGMA 413 GL ++ + RN +L S+ GL P P P +I+ +L + M Sbjct: 450 GLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLDSNPGAINTGVPEVDQILTVLLTTEMF 509 Query: 414 IGAITAIVLD 423 +G A +LD Sbjct: 510 VGGCLAFILD 519 >gi|5032233 sodium-dependent vitamin C transporter-1; yolk sac permease-like molecule 3 [Homo sapiens] >gi|3789785|gb|AAC78804.1| (AF058317) yolk sac permease-like molecule 3 [Homo sapiens] Length = 598 Score = 195 bits (490), Expect = 9e-49 Identities = 148/490 (30%), Positives = 232/490 (47%), Gaps = 79/490 (16%) Query: 5 VLVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTA--VGLSKEEISIMIQAVLLAM 62 +L K+++ ILLG QH+ T+ VP ++ A VG S+ +I + + Sbjct: 31 MLYKIEDVPPWYLCILLGFQHIHDCLRGTIAVPFLLAEALCVGHSQTLHCQLIGTIFTCV 90 Query: 63 GIATLLQTTIGSRYPIVQGSSFAFIPGLISI----------------GKSLGMAAT---- 102 GI TL+QTT+G R P+ Q S+FAF+ +I SL + + Sbjct: 91 GITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEIYGNSSLPLNTSHIWH 150 Query: 103 ------EGALIVGGIIEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNF 156 +GA++V ++E +IG G+ G + PL T+ LIG S+ A Sbjct: 151 PRNREVQGAIMVSSVVEVVIGLLGLPGALLNSLGPLTVTPTVSLIGLSVFQAA------- 203 Query: 157 YADPSGS--SIPRATIVALV---------TFITTVY-----VALKAKGPIRAMPVIAGAL 200 D GS I +I+ ++ TF+ VY + L + P++ + Sbjct: 204 -GDRPGSHWGISACSILLIILFSQYLRNLTFLLPVYRWGKGLTLLRIQIFKMFPIMLAIM 262 Query: 201 VGYLVSVPLGLAN----------FQ--------LVKELPLVSLPRPFPWGIPEFNLTAIV 242 +L+ + L L + FQ ++ P + +P P WG+P A++ Sbjct: 263 TVWLLCIVLTLTDVLPTDPKAIGFQARTDARGDIMAIAPWIRIPYPCQWGLPTVTAAAVL 322 Query: 243 TLLFAFMVSIIESVGDYHAISAIAEAPITNKH-INRGIMSEGIACSIAGILGAC-GTTSY 300 + A + IIES+GDY+A + +A AP H INRGI +EGI C IAG+LG G+TS Sbjct: 323 GMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSS 382 Query: 301 SENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVT 360 S NIG++ +TKV SR VVQ G I++VL KF + AS+P P+LGG+ +L+GMI+ Sbjct: 383 SPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKFTALFASLPDPILGGMFCSLFGMITAV 442 Query: 361 GLRLIKDKVELNDRNTLILATSLIVGLGAPQLPPK-------FLAHFPRIVASILESGMA 413 GL ++ + RN +L S+ GL P + +I+ +L + M Sbjct: 443 GLSNLQFVALNSSRNLFVLGFSMFFGLTLPNYLESNPGAINTGILEVDQILIVLLTTEMF 502 Query: 414 IGAITAIVLD 423 +G A +LD Sbjct: 503 VGGCLAFILD 512 >gi|11421164 solute carrier family 23 (nucleobase transporters), member 1 [Homo sapiens] >gi|7513342|pir||JC7095 sodium-dependent vitamin C (ascorbate) transporter 2 - human >gi|6048257|emb|CAB58120.1| (AJ269478) sodium-dependent vitamin C transporter 2, SVCT2 [Homo sapiens] >gi|8886524|gb|AAF80493.1|AF164142_1 (AF164142) sodium-dependent vitamin transporter 2 [Homo sapiens] Length = 650 Score = 192 bits (484), Expect = 5e-48 Identities = 148/484 (30%), Positives = 228/484 (46%), Gaps = 90/484 (18%) Query: 19 ILLGLQHVLAMFGATVTVPLVVGTA--VGLSKEEISIMIQAVLLAMGIATLLQTTIGSRY 76 I LGLQH L F T+ VP ++ A VG + S +I + +GI TLLQTT G R Sbjct: 103 IFLGLQHYLTCFSGTIAVPFLLADAMCVGYDQWATSQLIGTIFFCVGITTLLQTTFGCRL 162 Query: 77 PIVQGSSFAFIP---GLISIGK--------SLGMAATE----------------GALIVG 109 P+ Q S+FAF+ ++S+ K S+ E GA+I+ Sbjct: 163 PLFQASAFAFLAPARAILSLDKWKCNTTDVSVANGTAELLHTEHIWYPRIREIQGAIIMS 222 Query: 110 GIIEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRAT 169 +IE +IG G+ G + + PL T+ LIG S F + +G A Sbjct: 223 SLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLS--------GFQAAGERAGKHWGIAM 274 Query: 170 IVALVTFITTVYVALKAKGPI-----------------RAMPVIAGALVGYLV------- 205 + + + + Y A K P+ + P+I LV +L+ Sbjct: 275 LTIFLVLLFSQY-ARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSWLLCFIFTVT 333 Query: 206 ------SVPLGL-----ANFQLVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIE 254 S G A ++ P +P PF WG+P + ++ +L A + SIIE Sbjct: 334 DVFPPDSTKYGFYARTDARQGVLLVAPWFKVPYPFQWGLPTVSAAGVIGMLSAVVASIIE 393 Query: 255 SVGDYHAISAIAEAPITNKH-INRGIMSEGIACSIAGILGAC-GTTSYSENIGLVALTKV 312 S+GDY+A + ++ AP H INRGI EG++C + GI G G+TS S NIG++ +TKV Sbjct: 394 SIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKV 453 Query: 313 ASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVELN 372 SR V+Q G +++ L + KF+ + AS+P PVLG L L+GMI+ GL ++ ++LN Sbjct: 454 GSRRVIQCGAALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQ-FIDLN 512 Query: 373 -DRNTLILATSLIVGLGAPQLPPKFLAHFP---------RIVASILESGMAIGAITAIVL 422 RN +L S+ GL + P +L P +++ +L + M +G A +L Sbjct: 513 SSRNLFVLGFSIFFGL----VLPSYLRQNPLVTGITGIDQVLNVLLTTAMFVGGCVAFIL 568 Query: 423 DQLL 426 D + Sbjct: 569 DNTI 572 >emb|CAB89870.1| (AJ132624) uracil transporter [Lactococcus lactis] Length = 430 Score = 192 bits (484), Expect = 5e-48 Identities = 136/442 (30%), Positives = 238/442 (53%), Gaps = 44/442 (9%) Query: 5 VLVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGI 64 +++KVDEK + L QH+ AMFG+TV VP++VG ++ LL+ G+ Sbjct: 6 IILKVDEKPAASQWFGLSFQHLFAMFGSTVLVPILVGINPAIA-----------LLSSGL 54 Query: 65 ATLLQTTIGS-RYPIVQGSSFAFIPGLISIGKSLGMAATEGALIVGGI---IEALIGGTG 120 TL ++ + P GSSFA+I + + K+ GM A + GG+ I ALI Sbjct: 55 GTLAHMSVTKFKVPAYMGSSFAYIGAMTLLMKNGGMPAIAQGAMTGGLVYLIVALIVKFA 114 Query: 121 IVGKVKRLFTPLVTGVTIMLIGFSLADVAVK-YFFNFYADPSGSSIPRATIVALVTFITT 179 G + ++ P+V G +M+IG SLA A+ + A+ G S+ I+AL+T ++ Sbjct: 115 GKGWIDKVLPPIVVGPIVMVIGLSLAPTAINDAMYTDVANLKGYSLAYI-IIALITVLSI 173 Query: 180 VYVALKAKGPIRAMPVIAGALVGYLVSVPLG------LANFQLVKELPLVSLPRPFPWGI 233 V ++ KG + +P++ G + GY+ ++ +G + +F + + ++LP P I Sbjct: 174 VVYSIYGKGFLSVVPILLGIITGYVAAMIIGKITGMNIVSFTGISQAKWLTLP---PMEI 230 Query: 234 P------EFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEAPITNKH-INRGIMSEGIAC 286 P F +AI+T+ V++ E G ++++ + + + + + +G+A Sbjct: 231 PFASYKWAFYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKKDYFKEPGLEKTLTGDGLAQ 290 Query: 287 SIAGILGACGTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVL 346 IAG +GA TSY ENIG++A+TK+ S YV+ ++ +V+S K +L S+PAPV+ Sbjct: 291 IIAGFIGAPPVTSYGENIGVMAITKIHSIYVIAGAAVLAIVVSFVGKITALLQSIPAPVI 350 Query: 347 GGLTIALYGMISVTGLR-LIKDKVELN-DRNTLILATSLIVGLGAPQLPPKFLAHFPRIV 404 GG +IAL+G+I+ +GL+ L+++KV+ + RN LI + L++G+G + I Sbjct: 351 GGASIALFGVIAASGLKILVENKVDFDIKRNLLISSVVLVIGIGGMII---------NIT 401 Query: 405 ASILESGMAIGAITAIVLDQLL 426 ++ S +AI I IVL+ +L Sbjct: 402 QNLQISSVAIATILGIVLNLVL 423 >gi|4827020 solute carrier family 23 (nucleobase transporters), member 1; sodium-dependent vitamin C transporter-2 [Homo sapiens] >gi|3789789|gb|AAC78806.1| (AF058319) yolk sac permease-like molecule 2 [Homo sapiens] Length = 650 Score = 192 bits (482), Expect = 8e-48 Identities = 148/484 (30%), Positives = 228/484 (46%), Gaps = 90/484 (18%) Query: 19 ILLGLQHVLAMFGATVTVPLVVGTA--VGLSKEEISIMIQAVLLAMGIATLLQTTIGSRY 76 I LGLQH L F T+ VP ++ A VG + S +I + +GI TLLQTT G R Sbjct: 103 IFLGLQHYLTCFSGTIAVPFLLADAMCVGYDQWATSQLIGTIFFCVGITTLLQTTFGCRL 162 Query: 77 PIVQGSSFAFIP---GLISIGK--------SLGMAATE----------------GALIVG 109 P+ Q S+FAF+ ++S+ K S+ E GA+I+ Sbjct: 163 PLFQTSAFAFLAPARAILSLDKWKCNTTDVSVANGTAELLHTEHIWYPRIREIQGAIIMS 222 Query: 110 GIIEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRAT 169 +IE +IG G+ G + + PL T+ LIG S F + +G A Sbjct: 223 SLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLS--------GFQAAGERAGKHWGIAM 274 Query: 170 IVALVTFITTVYVALKAKGPI-----------------RAMPVIAGALVGYLV------- 205 + + + + Y A K P+ + P+I LV +L+ Sbjct: 275 LTIFLVLLFSQY-ARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSWLLCFIFTVT 333 Query: 206 ------SVPLGL-----ANFQLVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIE 254 S G A ++ P +P PF WG+P + ++ +L A + SIIE Sbjct: 334 DVFPPDSTKYGFYARTDARQGVLLVAPWFKVPYPFQWGLPTVSAAGVIGMLSAVVASIIE 393 Query: 255 SVGDYHAISAIAEAPITNKH-INRGIMSEGIACSIAGILGAC-GTTSYSENIGLVALTKV 312 S+GDY+A + ++ AP H INRGI EG++C + GI G G+TS S NIG++ +TKV Sbjct: 394 SIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKV 453 Query: 313 ASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVELN 372 SR V+Q G +++ L + KF+ + AS+P PVLG L L+GMI+ GL ++ ++LN Sbjct: 454 GSRRVIQCGAALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQ-FIDLN 512 Query: 373 -DRNTLILATSLIVGLGAPQLPPKFLAHFP---------RIVASILESGMAIGAITAIVL 422 RN +L S+ GL + P +L P +++ +L + M +G A +L Sbjct: 513 SSRNLFVLGFSIFFGL----VLPSYLRQNPLVTGITGIDQVLNVLLTTAMFVGGCVAFIL 568 Query: 423 DQLL 426 D + Sbjct: 569 DNTI 572 >gb|AAC78807.1| (AF058320) yolk sac permease-like molecule 2 [Sus scrofa] Length = 650 Score = 191 bits (480), Expect = 1e-47 Identities = 150/484 (30%), Positives = 227/484 (45%), Gaps = 90/484 (18%) Query: 19 ILLGLQHVLAMFGATVTVPLVVGTA--VGLSKEEISIMIQAVLLAMGIATLLQTTIGSRY 76 I LGLQH L F T+ VP ++ A VG + S +I +L +GI TLLQTT G R Sbjct: 102 IFLGLQHYLTCFSGTIAVPFLLADAMCVGYDQWATSQLIGTILFCVGITTLLQTTFGCRL 161 Query: 77 PIVQGSSFAFIP---GLISIGK--------SLGMAATE----------------GALIVG 109 P+ Q S+FAF+ ++S+ K S+ TE GA+I+ Sbjct: 162 PLFQASAFAFLAPARAILSLDKWKCNTTDVSVANGTTELLHTEHMWYPRIREIQGAIIMS 221 Query: 110 GIIEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRAT 169 +IE +IG G+ G + + PL T+ LIG S F + +G A Sbjct: 222 SLIEVVIGLLGLPGALLKYIGPLGITPTVALIGLS--------GFQAAGERAGKHWGIAM 273 Query: 170 IVALVTFITTVYVALKAKGPI-----------------RAMPVIAGALVGYLV------- 205 + + + + Y A K P+ + P+I LV +L+ Sbjct: 274 LTIFLLLLFSQY-ARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSWLLCFIFTVT 332 Query: 206 ------SVPLGL-----ANFQLVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIE 254 S G A ++ P +P PF WG+P + ++ +L A + SIIE Sbjct: 333 DVFPPDSTKYGFYARTDARQGVLLVAPWFKVPYPFQWGLPTVSAAGVIGMLSAVVASIIE 392 Query: 255 SVGDYHAISAIAEAPITNKH-INRGIMSEGIACSIAGILGAC-GTTSYSENIGLVALTKV 312 S+GDY+A + ++ AP H INRGI EG++C + GI G G+TS S NIG++ +TKV Sbjct: 393 SIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKV 452 Query: 313 ASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVELN 372 SR V+Q G L + KF+ + AS+P PVLG L L+GMI+ GL ++ ++LN Sbjct: 453 GSRRVIQYGAASCCALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQ-FIDLN 511 Query: 373 -DRNTLILATSLIVGLGAPQLPPKFLAHFP---------RIVASILESGMAIGAITAIVL 422 RN +L S+ GL + P +L P +++ +L + M +G A +L Sbjct: 512 SSRNLFVLGFSIFFGL----VLPSYLRQNPLVTGITGVDQVLNVLLTTAMFVGGCVAFIL 567 Query: 423 DQLL 426 D + Sbjct: 568 DNTI 571 >gi|9055344 solute carrier family 23, (nucleobase transporters) member 1; sodium-dependent vitamin C transporter [Mus musculus] >gi|6970492|dbj|BAA90751.1| (AB038145) sodium-dependent vitamin C transporter SVCT2 [Mus musculus] Length = 592 Score = 191 bits (480), Expect = 1e-47 Identities = 150/482 (31%), Positives = 229/482 (47%), Gaps = 88/482 (18%) Query: 19 ILLGLQHVLAMFGATVTVPLVVGTA--VGLSKEEISIMIQAVLLAMGIATLLQTTIGSRY 76 I LGLQH L F T+ VP ++ A VG + S +I + +GI TLLQTT G R Sbjct: 47 IFLGLQHYLTCFSGTIAVPFLLADAMCVGDDQWATSQLIGTIFFCVGITTLLQTTFGCRL 106 Query: 77 PIVQGSSFAFIP---GLISIGK----------SLGMAAT------------EGALIVGGI 111 P+ Q S+FAF+ ++S+ K + G A +GA+I+ + Sbjct: 107 PLFQASAFAFLAPARAILSLDKWKCNTTEITVANGTAELLEHIWHPRIQEIQGAIIMSSL 166 Query: 112 IEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIV 171 IE +IG G+ G + R PL T+ LIG S F + +G A + Sbjct: 167 IEVVIGLLGLPGALLRYIGPLTITPTVALIGLS--------GFQAAGERAGKHWGIAMLT 218 Query: 172 ALVTFITTVYVALKAKGPI-----------------RAMPVIAGALVGYLV--------- 205 + + + Y A K P+ + P+I LV +L+ Sbjct: 219 IFLVLLFSQY-ARNVKFPLPIYKSKKGWTAYKFQLFKMFPIILAILVSWLLCFIFTVTDV 277 Query: 206 ----SVPLGL-----ANFQLVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESV 256 S G A ++ P +P PF WG+P + ++ +L A + SIIES+ Sbjct: 278 FPSNSTDYGYYARTDARKGVLLVAPWFKVPYPFQWGMPTVSAAGVIGMLSAVVASIIESI 337 Query: 257 GDYHAISAIAEAPITNKH-INRGIMSEGIACSIAGILGAC-GTTSYSENIGLVALTKVAS 314 GDY+A + ++ AP H INRGI EG++C + GI G G+TS S NIG++ +TKV S Sbjct: 338 GDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKVGS 397 Query: 315 RYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVELN-D 373 R V+Q G +++ L + KF+ + AS+P PVLG L L+GMI+ GL ++ ++LN Sbjct: 398 RRVIQYGAALMLGLGMVGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQ-FIDLNSS 456 Query: 374 RNTLILATSLIVGLGAPQLPPKFLAHFP---------RIVASILESGMAIGAITAIVLDQ 424 RN +L S+ GL + P +L P +I+ +L + M +G A +LD Sbjct: 457 RNLFVLGFSIFFGL----VLPSYLRQNPLVTGITGIDQILNVLLTTAMFVGGCVAFILDN 512 Query: 425 LL 426 + Sbjct: 513 TI 514 >gi|8394384 sodium-coupled ascorbic acid transporter 2 [Rattus norvegicus] >gi|4836174|gb|AAD30368.1|AF080453_1 (AF080453) sodium-coupled ascorbic acid transporter SVCT2 [Rattus norvegicus] Length = 592 Score = 190 bits (479), Expect = 2e-47 Identities = 148/482 (30%), Positives = 229/482 (46%), Gaps = 88/482 (18%) Query: 19 ILLGLQHVLAMFGATVTVPLVVGTA--VGLSKEEISIMIQAVLLAMGIATLLQTTIGSRY 76 I LGLQH L F T+ VP ++ A VG + S +I + +GI TLLQTT G R Sbjct: 47 IFLGLQHYLTCFSGTIAVPFLLADAMCVGDDQWATSQLIGTIFFCVGITTLLQTTFGCRL 106 Query: 77 PIVQGSSFAFIP---GLISIGK----------SLGMAAT------------EGALIVGGI 111 P+ Q S+FAF+ ++S+ K + G A +GA+I+ + Sbjct: 107 PLFQASAFAFLAPARAILSLDKWKCNTTEITVANGTAELLEHIWHPRIQEIQGAIIMSSL 166 Query: 112 IEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIV 171 IE +IG G+ G + R PL T+ LIG S F + +G A + Sbjct: 167 IEVVIGLLGLPGALLRYIGPLTITPTVALIGLS--------GFQAAGERAGKHWGIAMLT 218 Query: 172 ALVTFITTVYVALKAKGPI-----------------RAMPVIAGALVGYLV--------- 205 + + + Y A K P+ + P+I LV +L+ Sbjct: 219 IFLVLLFSQY-ARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSWLLCFIFTVTDV 277 Query: 206 ----SVPLGL-----ANFQLVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESV 256 S G A ++ P +P PF WG+P + ++ +L A + SIIES+ Sbjct: 278 FPSNSTDYGYYARTDARKGVLLVAPWFKVPYPFQWGMPTVSAAGVIGMLSAVVASIIESI 337 Query: 257 GDYHAISAIAEAPITNKH-INRGIMSEGIACSIAGILGAC-GTTSYSENIGLVALTKVAS 314 GDY+A + ++ AP H INRGI EG++C + G+ G G+TS S NIG++ +TKV S Sbjct: 338 GDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGVFGTGNGSTSSSPNIGVLGITKVGS 397 Query: 315 RYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVELN-D 373 R V+Q G +++ L + KF+ + AS+P PVLG L L+GMI+ GL ++ ++LN Sbjct: 398 RRVIQYGAALMLGLGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQ-FIDLNSS 456 Query: 374 RNTLILATSLIVGLGAPQLPPKFLAHFP---------RIVASILESGMAIGAITAIVLDQ 424 RN +L S+ GL + P +L P +++ +L + M +G A +LD Sbjct: 457 RNLFVLGFSIFFGL----VLPSYLRQNPLVTGITGIDQVLNVLLTTAMFVGGCVAFILDN 512 Query: 425 LL 426 + Sbjct: 513 TI 514 >gb|AAD11783.1| (AF092511) nucleobase transporter-like 1 protein [Homo sapiens] Length = 650 Score = 189 bits (475), Expect = 5e-47 Identities = 144/484 (29%), Positives = 224/484 (45%), Gaps = 90/484 (18%) Query: 19 ILLGLQHVLAMFGATVTVPLVVGTA--VGLSKEEISIMIQAVLLAMGIATLLQTTIGSRY 76 I LGLQH L F T+ VP ++ A VG + S + + +GI TLLQTT G R Sbjct: 103 IFLGLQHYLTCFSGTIAVPFLLADAMCVGYDQWATSQLTGTIFFCVGITTLLQTTFGCRL 162 Query: 77 PIVQGSSFAFIPGL---------------ISIGKSLG------------MAATEGALIVG 109 P+ Q S+FAF+ +S+ + +GA+I+ Sbjct: 163 PLFQASAFAFLAPARAILSSDKWKCNTTDVSVANGTAELLHTEHIWYPRIREVQGAIIMS 222 Query: 110 GIIEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRAT 169 +IE +IG G+ G + + PL T+ LIG S F + +G A Sbjct: 223 SLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLS--------GFQAAGERAGKHWGIAM 274 Query: 170 IVALVTFITTVYVALKAKGPI-----------------RAMPVIAGALVGYLV------- 205 + + + + Y A K P+ + P+I LV +L+ Sbjct: 275 LTIFLVLLFSQY-ARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSWLLCFIFTVT 333 Query: 206 ------SVPLGL-----ANFQLVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIE 254 S G A ++ P +P PF WG+P + ++ +L A + SIIE Sbjct: 334 DVFPPDSTKYGFYARTDARQGVLLVAPWFKVPYPFQWGLPTVSAAGVIGMLSAVVASIIE 393 Query: 255 SVGDYHAISAIAEAPITNKH-INRGIMSEGIACSIAGILGAC-GTTSYSENIGLVALTKV 312 S+GDY+A + ++ AP H INRGI EG++C + GI G G+TS S NIG++ +TKV Sbjct: 394 SIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKV 453 Query: 313 ASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVELN 372 SR V+Q G +++ L + KF+ + AS+P PVLG L L+GMI+ GL ++ ++LN Sbjct: 454 GSRRVIQCGAALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQ-FIDLN 512 Query: 373 -DRNTLILATSLIVGLGAPQLPPKFLAHFP---------RIVASILESGMAIGAITAIVL 422 RN +L S+ GL + P +L P +++ +L + M +G A +L Sbjct: 513 SSRNLFVLGFSIFFGL----VLPSYLRQNPLVTGITGIDQVLNVLLTTAMFVGGCVAFIL 568 Query: 423 DQLL 426 D + Sbjct: 569 DNTI 572 >pir||F72329 uracil permease - Thermotoga maritima (strain MSB8) >gi|4981350|gb|AAD35901.1|AE001749_4 (AE001749) uracil permease [Thermotoga maritima] Length = 399 Score = 189 bits (474), Expect = 7e-47 Identities = 132/423 (31%), Positives = 223/423 (52%), Gaps = 44/423 (10%) Query: 12 KVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLL-QT 70 KV + LL LQH +AMFGATV VPL+ G + LL GI TL+ Sbjct: 9 KVSGWRWFLLALQHFVAMFGATVLVPLITG-----------LDPLVALLTAGIGTLIFHF 57 Query: 71 TIGSRYPIVQGSSFAFIPGLISIGKSLG-MAATEGALIVGG---IIEALIGGTGIVGKVK 126 G P+ GSSFAFI ++++ + G +A G + V G ++ ALI KVK Sbjct: 58 VTGGIVPVFLGSSFAFIAPILAVKEIYGDLAYATGGIFVAGLFYVLYALIVKAVGPEKVK 117 Query: 127 RLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITTVYVALKA 186 ++ P+VTG IM+IG +L+ VA++ + S P +AL+ T V+V+ Sbjct: 118 KILPPVVTGSMIMVIGLTLSPVAIQM--------ASSDWP----LALIVIATVVFVSTMT 165 Query: 187 KGPIRAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLTAIVTLLF 246 +G +PVI G +VGY+ + +G + ++ PL S+P+ +P+F+ AI ++ Sbjct: 166 RGFFSMVPVITGVVVGYVAGLFMGKIDTSVIVSTPLFSVPKVM---LPKFDYGAIFMIVP 222 Query: 247 AFMVSIIESVGDYHAISAIAEAPITNKH-INRGIMSEGIACSIAGILGACGTTSYSENIG 305 + + +E +GD A+ +K ++R ++ +G+A ++AG+LG T+YSEN G Sbjct: 223 VTLATFMEHLGDITTNGAVVGKNFFDKPGLHRTLLGDGLATAVAGLLGGPANTTYSENTG 282 Query: 306 LVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLR-L 364 ++ALT+V V++ ++ + + KF IL ++P V+GG+++ L+GMI+ G+R + Sbjct: 283 VLALTRVYDPSVLRGAALVAIFAAFVSKFGAILQTIPQAVMGGVSLILFGMITSVGVRTM 342 Query: 365 IKDKVELN-DRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAITAIVLD 423 + +V+ + RN +I A L VG+G L V + G+ + A+ I L+ Sbjct: 343 VNAEVDFSKPRNLMITALMLTVGIGGAVLK----------VGRVELKGIGLAALVGIFLN 392 Query: 424 QLL 426 +L Sbjct: 393 LIL 395 >pir||T20137 hypothetical protein C51E3.6 - Caenorhabditis elegans >gi|3875153|emb|CAB01641.1| (Z78410) Similarity to Mouse YSPL-1 protein (TR:G1002425), contains similarity to Pfam domain: PF00860 (Xanthine/uracil permeases family), Score=607.0, E-value=3.5e-179, N=1 [Caenorhabditis elegans] Length = 555 Score = 187 bits (470), Expect = 2e-46 Identities = 127/473 (26%), Positives = 230/473 (47%), Gaps = 84/473 (17%) Query: 18 AILLGLQHVLAMFGATVTVPLVV------GTAVGLSKEEISIMIQAVLLAMGIATLLQTT 71 A+L GLQ V+ A +TVPL++ G+++ + ++ + I + ++ GI+T++QT Sbjct: 32 ALLYGLQQVMVCVSALLTVPLIMADSMCPGSSIAVLRQTL---ISSTFVSSGISTIIQTL 88 Query: 72 IGSRYPIVQGSSFAFIP---GLISIGKSL----------------GMAATEGALIVGGII 112 G R ++QG++FA++P G +S+ ++ +A +G LI + Sbjct: 89 FGMRLALLQGTAFAYVPSVQGFMSLPENTCNATESDYVPEEVYYGKLALLQGCLIASSFV 148 Query: 113 EALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVA 172 LIG TG+VG + + PL ++L+ FS D+ V + + IV Sbjct: 149 PILIGATGLVGMLTKFIGPLTVSPLMLLLAFSQVDLMVTHISKHWV----------AIVQ 198 Query: 173 LVTFITTVYVALKAKGPIRAM----------------PVIAGALVGYLVSVPLGLANFQ- 215 VT T+ + K P+ + P + ++ V L + N Sbjct: 199 AVTLFATILYLAEVKVPVPGIKNGKFHWYRINLFGQYPYLIAICTSWIFCVALTIFNLTP 258 Query: 216 --------------LVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHA 261 +++E + +P P +G P+FN + L + M S+ ESVGDYHA Sbjct: 259 EGSAARVDKNISLAVIRESSWLEVPYPGKFGPPQFNTGLFLLFLLSAMTSVFESVGDYHA 318 Query: 262 ISAIAEA-PITNKHINRGIMSEGIACSIAGILG-ACGTTSYSENIGLVALTKVASRYVVQ 319 + ++E P + INRGI++EG+ I+G+LG G T+++ENIG++ +T+VASR+ + Sbjct: 319 AARVSEERPPPSHAINRGILAEGLGSLISGLLGPGVGMTTHTENIGVIGVTRVASRWTMV 378 Query: 320 IGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVELNDRNTLIL 379 + G+ L++L L K +L+++P P++GG+ + M+ + ++ RN I Sbjct: 379 MAGVFLIILGLITKIGALLSTIPDPLVGGVLASSMAMVVGVAVSNLQTVDMTLSRNMGIF 438 Query: 380 ATSLIVGLGAPQLPPKFLAHFP---------RIVASILESGMAIGAITAIVLD 423 S++ GL + PK+ FP +I+ +L+ M +GA+ A +LD Sbjct: 439 GFSMMFGL----IVPKYFKLFPVDTDWGWFNQILNVLLQMPMFVGALCACILD 487 >pir||D82111 uracil permease VC2171 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9656724|gb|AAF95316.1| (AE004288) uracil permease [Vibrio cholerae] Length = 417 Score = 186 bits (467), Expect = 5e-46 Identities = 135/419 (32%), Positives = 218/419 (51%), Gaps = 33/419 (7%) Query: 17 KAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTTIGSR- 75 K + G Q + FGA V VPL+ G ++ L G+ TLL I R Sbjct: 2 KNAIQGAQMLFVAFGALVLVPLLTGLDPNVA-----------LFGAGLGTLLFQLITRRS 50 Query: 76 YPIVQGSSFAFIPGLISIGKSLGMAATEGALIVGGIIEALIGG---TGIVGKVKRLFTPL 132 PI SSFAFI ++ ++ G+ AT G L+ G + ++GG V + +L P+ Sbjct: 51 VPIFLASSFAFIAPIMFGIQTWGIPATMGGLMAAGAVYIVLGGIIKVRGVAIIHKLLPPV 110 Query: 133 VTGVTIMLIGFSLADVAVKYFFNFYADPSGSSI-PRATI-VALVTFITTVYVALKAKGPI 190 V G IM+IG LA AV D S + P+A + ++ ++ + TV ++ AKG Sbjct: 111 VVGPVIMVIGLGLAPAAVNMALGKTGDGSVQLVDPQAALWISCISLLVTVVFSVFAKGFF 170 Query: 191 RAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMV 250 + +P++AG + GY VS+ +G+ +F V++ ++LP + PEFN+ AI+ ++ + Sbjct: 171 KLVPILAGIVSGYAVSLVMGVVSFAAVEQAAWLALPN---FTFPEFNINAILFMIPVAIA 227 Query: 251 SIIESVGDYHAISAIAEAPITNKH-INRGIMSEGIACSIAGILGACGTTSYSENIGLVAL 309 +E VGD AIS + K ++R I +G+A A +LGA T+YSE G V L Sbjct: 228 PAVEHVGDMLAISNVTNKDYLKKPGLHRTIAGDGVATMAATMLGAPPNTTYSEVTGAVML 287 Query: 310 TKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLR-LIKDK 368 T+ + ++ I +VL+L K +L ++P PV+GG+ I L+G I+ GL LIK++ Sbjct: 288 TRAFNPAIMTWAAITAIVLALVGKLGALLQTIPVPVMGGIMILLFGSIATVGLNTLIKNQ 347 Query: 369 VELN-DRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAITAIVLDQLL 426 V+L+ RN +I+A +L+ G+G V G+++ I AIVL+ +L Sbjct: 348 VDLHKSRNLVIVAVTLVFGIGGMAFG----------VGDFSLQGVSLCGIVAIVLNLVL 396 >pir||E83066 uracil permease PA4647 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9950900|gb|AAG08034.1|AE004878_12 (AE004878) uracil permease [Pseudomonas aeruginosa] Length = 427 Score = 185 bits (464), Expect = 1e-45 Identities = 133/421 (31%), Positives = 213/421 (50%), Gaps = 34/421 (8%) Query: 17 KAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLL-QTTIGSR 75 + +L G Q + FGA V +PL+ G ++ L G+ TLL Q G + Sbjct: 11 RQVLSGAQMLFVAFGALVLMPLITGLDPNVA-----------LFTAGLGTLLFQLVTGRQ 59 Query: 76 YPIVQGSSFAFIPGLISIGKSLGMAATEGALIVGGIIEALIG------GTGIVGKVKRLF 129 P+ SSFAFI +I G+AAT G ++ G + +G GTG + K L Sbjct: 60 VPVFLASSFAFITPIILAKGQFGLAATMGGVVAAGFVYTFMGLAVKIKGTGFIDK---LL 116 Query: 130 TPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPR-ATIVALVTFITTVYVALKAKG 188 P+V G I+ IG ++A +A D S R A ++++ +TT+ VA+ KG Sbjct: 117 PPVVIGPVIISIGLAMAPIAANMAMGKAGDGSELLPYRTAMMISMPALLTTLVVAVFGKG 176 Query: 189 PIRAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAF 248 R +P+IAG LVG+ +S G+ + + P + LP+ + PEFN AI+ ++ Sbjct: 177 IFRLVPIIAGVLVGFALSFVFGVVDTAAIVAAPWLELPK---FTAPEFNWQAILFIVPVA 233 Query: 249 MVSIIESVGDYHAISAIAEAPITNKH-INRGIMSEGIACSIAGILGACGTTSYSENIGLV 307 + IE +G A+ + K ++R ++ +G+A S AG+ G T+Y+E G V Sbjct: 234 LAPAIEHIGGVIAVGGVTGQDYLKKPGLHRTLLGDGLATSAAGLFGGPPNTTYAEVTGAV 293 Query: 308 ALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLR-LIK 366 LTK + ++ +I + L+ KF IL S+P PV+GG+ L+G I+ G+ LI+ Sbjct: 294 MLTKNYNPKIMTWAAVIAITLAFVGKFGAILQSIPVPVMGGILCLLFGTIASVGMNTLIR 353 Query: 367 DKVELND-RNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAITAIVLDQL 425 KV+L++ RN +I++ +L+ G+G L I G+A+ AI AIVL+ L Sbjct: 354 HKVDLSEARNLVIVSVTLVFGIGG------VLIGSGTGPDDIGLKGIALCAIVAIVLNLL 407 Query: 426 L 426 L Sbjct: 408 L 408 >dbj|BAB06259.1| (AP001515) uracil transporter (permease) [Bacillus halodurans] Length = 444 Score = 179 bits (450), Expect = 5e-44 Identities = 133/427 (31%), Positives = 225/427 (52%), Gaps = 39/427 (9%) Query: 15 PRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTTIGS 74 P K ++L LQH+ AMFGAT+ VPL+V + ++ L++ G+ TL I Sbjct: 16 PHKWLILSLQHLCAMFGATILVPLLVDLSPAVA-----------LISSGLGTLAYLLITK 64 Query: 75 -RYPIVQGSSFAFIPGLISIGKSLGM-AATEGALIVG---GIIEALIGGTGIVGK--VKR 127 + P GSSFAFI +I++ G AA G+ VG G+ LI +VG+ + Sbjct: 65 GQVPAYLGSSFAFITPIIAVTAFGGPEAAMVGSFFVGLVYGVAALLIK---VVGRKWLMT 121 Query: 128 LFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRAT--IVALVTFITTVYVALK 185 + P+V G IM+IG LA VA+ + G + T +VA++T + T+ A+ Sbjct: 122 VLPPIVVGPVIMVIGLGLAGVAIDMAMMETIE-QGVQVFNGTFMLVAMITLLITIVAAVF 180 Query: 186 AKGPIRAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPR---PFPWGIPEFNLTAIV 242 KG +P++ G GY+ ++ +GL +FQ V E + P PF P T + Sbjct: 181 FKGFFGLVPMMFGIAGGYVTALFVGLIDFQAVYEAKWLVAPDFIVPFVTYTPTVEWTVLA 240 Query: 243 TLLFAFMVSIIESVGDYHAISAIAEAPITNKH-INRGIMSEGIACSIAGILGACGTTSYS 301 ++ V++ E +GD +S +A K ++R + +G+A IA LG T+Y Sbjct: 241 IMVPIAAVTLAEHIGDQMVLSKVAGKNFLEKPGLHRSLAGDGVATMIASFLGGPPNTTYG 300 Query: 302 ENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTG 361 ENIG++A+T+V S +V+ ++ +V K + +++++P V+GG++I L+G+I+ +G Sbjct: 301 ENIGVIAITRVFSVFVIGGAALLAIVFGFSGKISALISTIPQAVMGGVSILLFGVIASSG 360 Query: 362 LR-LIKDKVELND-RNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAITA 419 LR LI ++++L + RN +I + L++G+G +P I ++ GMA+ I Sbjct: 361 LRMLIDNEIQLGEKRNLIISSVILVIGIGGAFVP---------INENVQIPGMALATIIG 411 Query: 420 IVLDQLL 426 IVL +L Sbjct: 412 IVLHLVL 418 >sp|P50487|YCPX_CLOPE HYPOTHETICAL PROTEIN IN CPE 5'REGION >gi|1850805|emb|CAA50688.1| (X71844) purine permease [Clostridium perfringens] Length = 311 Score = 177 bits (445), Expect = 2e-43 Identities = 97/291 (33%), Positives = 173/291 (59%), Gaps = 5/291 (1%) Query: 138 IMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITTVYVALKAKGPIRAMPVIA 197 + LIG +L V++ + + +S+ VA+ I T+ + KG I + ++ Sbjct: 6 VALIGLTLLPVSIDWAAGGAGSANYASLENLA-VAMFVLIITLLLNNYGKGMISSASILI 64 Query: 198 GALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESVG 257 G +VGY+V +PLGL +F VKE +S P+ +G+ F+ A++ + A+ V+ I +VG Sbjct: 65 GIVVGYIVCIPLGLVDFTSVKEASWLSFPKILEFGVT-FDAKAVMAFIPAYFVATIGTVG 123 Query: 258 DYHAI-SAIAEAPITNKHINRGIMSEGIACSIAGILGACGTTSYSENIGLVALTKVASRY 316 + I +K + G++S+G+ ++ G++G+C TS+S+NIG+++LTKVASR+ Sbjct: 124 MLKSYWRDILLLIFGDKRVAAGVLSDGVGSALGGLVGSCPNTSFSQNIGIISLTKVASRH 183 Query: 317 VVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVELNDRNT 376 V + GI+LV+L PK A I+ +P PVLGG+ I ++G ++ G+R + + ++L +RN Sbjct: 184 VAVMAGILLVILGFLPKVAAIITGIPNPVLGGVGIMMFGTVAAAGIRTLSN-IKLTERNL 242 Query: 377 LILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAITAIVLDQLLR 427 LI+A S+ +GLG P + + P + I SG++ G I A++L+ +L+ Sbjct: 243 LIIAISMGLGLGV-TFRPDVIHNLPEAIRMIFSSGISTGTIAALILNAVLK 292 >sp|P41006|PYRP_BACCL URACIL PERMEASE (URACIL TRANSPORTER) >gi|481579|pir||S38893 uracil transport protein - Bacillus caldolyticus >gi|431231|emb|CAA53697.1| (X76083) uracil permease [Bacillus caldolyticus] Length = 432 Score = 177 bits (444), Expect = 2e-43 Identities = 132/429 (30%), Positives = 215/429 (49%), Gaps = 55/429 (12%) Query: 19 ILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTTIGS-RYP 77 I L LQH+ AMFGAT+ VP +VG ++ LL G+ TL I + P Sbjct: 18 ITLSLQHLFAMFGATILVPYLVGLDPSIA-----------LLTSGLGTLAFLLITKWQVP 66 Query: 78 IVQGSSFAFIPGLISIGKSLGMAATEGALIVGGIIEALIGGTG--IVGK-----VKRLFT 130 GSSFA+I +I+ + G GA ++G + L+ G I+ K V +L Sbjct: 67 AYLGSSFAYIAPIIAAKTAGG----PGAAMIGSFLAGLVYGVVALIIKKAGYRWVMKLLP 122 Query: 131 PLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITTVYVALKAKGPI 190 P+V G I++IG LA AV N P G VALVT T+ ++ A+G + Sbjct: 123 PVVVGPVIIVIGLGLAGTAVGMAMN---GPDGKYSLLHFSVALVTLAATIVCSVLARGML 179 Query: 191 RAMPVIAGALVGYLVSVPLGLANFQLVKE----------LPLVSLPRPFPWGIPEFNLTA 240 +PV+ G +VGYL ++ +GL + V +P P W I Sbjct: 180 SLIPVLVGIVVGYLYALAVGLVDLSKVAAAKWFEWPDFLIPFADYPVRVTWEI------- 232 Query: 241 IVTLLFAFMVSIIESVGDYHAISAIAEAPITNKH-INRGIMSEGIACSIAGILGACGTTS 299 ++ ++ +V++ E +G +S + + K ++R I+ +G A I+ +LG T+ Sbjct: 233 VMLMVPVAIVTLSEHIGHQLVLSKVVGRDLIQKPGLHRSILGDGTATMISALLGGPPKTT 292 Query: 300 YSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISV 359 Y ENIG++A+T+V S YV+ +I + K +++S+P PV+GG++I L+G+I+ Sbjct: 293 YGENIGVLAITRVYSVYVLAGAAVIAIAFGFVGKITALISSIPTPVMGGVSILLFGIIAS 352 Query: 360 TGLR-LIKDKVELND-RNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAI 417 +GLR LI +V+ RN +I + L++G+G L +I S +GMA+ AI Sbjct: 353 SGLRMLIDSRVDFGQTRNLVIASVILVIGIGGAVL---------KISDSFQITGMALSAI 403 Query: 418 TAIVLDQLL 426 ++L+ +L Sbjct: 404 VGVLLNLIL 412 >dbj|BAB10858.1| (AB009053) permease 1 [Arabidopsis thaliana] Length = 532 Score = 176 bits (443), Expect = 3e-43 Identities = 128/412 (31%), Positives = 194/412 (47%), Gaps = 46/412 (11%) Query: 17 KAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTTIGSRY 76 +AILLG QH L M G TV +P + +G EE + +IQ +L GI TLLQT G+R Sbjct: 38 EAILLGFQHYLVMLGTTVLIPTALVPQMGGGYEEKAKVIQTILFVAGINTLLQTLFGTRL 97 Query: 77 PIVQGSSFAFIPGLISIGKSLG--------------MAATEGALIVGGIIEALIGGTGIV 122 P V G+S+ F+P ISI S M AT+GALIV ++ ++G +G+ Sbjct: 98 PAVVGASYTFVPTTISIILSGRFSDTSNPIDRFERIMRATQGALIVASTLQMILGFSGLW 157 Query: 123 GKVKRLFTPLVTGVTIMLIGFSL----------------ADVAVKYFFNFYAD---PSGS 163 V R +P+ + L+GF L ++ + F + Y SG Sbjct: 158 RNVVRFLSPISAVPLVGLVGFGLYEFGFPGVAKCIEIGLPELLILVFVSQYLPHVIKSGK 217 Query: 164 SIPRATIVALVTFITTVYVALKAKGPIRAMPVIAGALVGYLVSVPLGLANFQ--LVKELP 221 ++ V I +Y L G GA G + + ++ P Sbjct: 218 NVFDRFAVIFAVVIVWIYAHLLTVG---------GAYNGAAPTTQTSCRTDRAGIIGAAP 268 Query: 222 LVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEAPITNKHI-NRGIM 280 + +P PF WG P F+ ++ A V+++ES G + A+S A A + I +RGI Sbjct: 269 WIRVPWPFQWGAPSFDAGEAFAMMMASFVALVESTGAFVAVSRYASATMLPPSILSRGIG 328 Query: 281 SEGIACSIAGILGACGTTSYS-ENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILA 339 +G+A I+G+ G +S S EN GL+ALT+V SR VVQI ++ S+ KF + A Sbjct: 329 WQGVAILISGLFGTGAGSSVSVENAGLLALTRVGSRRVVQIAAGFMIFFSILGKFGAVFA 388 Query: 340 SMPAPVLGGLTIALYGMISVTGLRLIKDKVELNDRNTLILATSLIVGLGAPQ 391 S+PAP++ L + + GL ++ + R IL S+ +GL PQ Sbjct: 389 SIPAPIIAALYCLFFAYVGAGGLSFLQFCNLNSFRTKFILGFSVFLGLSIPQ 440 >sp|P45117|URAA_HAEIN PROBABLE URACIL PERMEASE (URACIL TRANSPORTER) >gi|1075426|pir||D64111 uracil transport protein homolog - Haemophilus influenzae (strain Rd KW20) >gi|1574157|gb|AAC22880.1| (U32802) uracil permease (uraA) [Haemophilus influenzae Rd] Length = 414 Score = 176 bits (442), Expect = 4e-43 Identities = 131/418 (31%), Positives = 217/418 (51%), Gaps = 36/418 (8%) Query: 17 KAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLL-QTTIGSR 75 K +GLQ + FGA V VPL+ G + LL G+ TLL Q G + Sbjct: 17 KQSFVGLQMLFVAFGALVLVPLITG-----------LDSNTALLTAGVGTLLFQFCTGKQ 65 Query: 76 YPIVQGSSFAFIPGLISIGKSLGMAATEGALIVGGII----EALIGGTGIVGKVKRLFTP 131 PI SSFAFI + ++ G+A T G L G++ L+ G ++R F P Sbjct: 66 VPIFLASSFAFIAPIQYGVQTWGIATTMGGLAFTGLVYFALSTLVKLRGAEA-LQRFFPP 124 Query: 132 LVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITTVYVALKAKGPIR 191 +V G I++IG LA +AV S + A +V++VT +TT+ VA+ AKG ++ Sbjct: 125 VVVGPVIIIIGMGLAPIAVDMSLG---KNSAYAYNDAVLVSMVTLLTTLSVAVFAKGLMK 181 Query: 192 AMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVS 251 +P++ G GY++ + LGL NFQ V + P SLP+ PEFNL AI+ +L + Sbjct: 182 LIPIMFGITAGYILCLFLGLINFQPVIDAPWFSLPK---LTTPEFNLEAILYMLPIAIAP 238 Query: 252 IIESVGDYHAISAIAEAPITNK-HINRGIMSEGIACSIAGILGACGTTSYSENIGLVALT 310 +E VG AIS++ K ++R ++ +GIA + A ++G T+Y+E G V LT Sbjct: 239 AVEHVGGIMAISSVTGKDFLKKPGLHRTLLGDGIATAAASLVGGPPNTTYAEVTGAVMLT 298 Query: 311 KVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGL-RLIKDKV 369 + + ++ + + +S K L+++P V+GG+ + ++G I+V G+ LI+ KV Sbjct: 299 RNFNPNIMTWAAVWAIAISFCGKVGAFLSTIPTIVMGGIMMLVFGSIAVVGMSTLIRGKV 358 Query: 370 ELND-RNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAITAIVLDQLL 426 ++ + RN I++ + G+G + V ++ G+++ AI AI+L+ +L Sbjct: 359 DVTEARNLCIISVVMTFGIGNMFVD----------VGNVSLKGISLCAIVAIILNLVL 406 >gb|AAC73019.1| (AC005824) putative membrane transporter [Arabidopsis thaliana] Length = 721 Score = 176 bits (441), Expect = 5e-43 Identities = 120/416 (28%), Positives = 190/416 (44%), Gaps = 49/416 (11%) Query: 22 GLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTTIGSRYPIVQG 81 GLQH L+M G+ + VPLV+ A+G S EE++ ++ VL GI TLL T+ GSR P++QG Sbjct: 186 GLQHYLSMLGSLILVPLVIVPAMGGSHEEVANVVSTVLFVSGITTLLHTSFGSRLPLIQG 245 Query: 82 SSFAFIPGLISIGKSLG-------------MAATEGALIVGGIIEALIGGTGIVGKVKRL 128 SF F+ ++I S M +GA+I+G +A++G +G++ + RL Sbjct: 246 PSFVFLAPALAIINSPEFQGLNGNNNFKHIMRELQGAIIIGSAFQAVLGYSGLMSLILRL 305 Query: 129 FTPLVTGVTIMLIGFSL-------------------------------ADVAVKYFFNFY 157 P+V T+ +G S V F Y Sbjct: 306 VNPVVVAPTVAAVGLSFYSYGFPLVGKCLEIGVVQILLVIIFALYLRKISVLSHRIFLIY 365 Query: 158 ADPSGSSIPRATIVALVTFITTVYVALKAKGPIRAMPVIAGALVGYLVSVPL-GLANFQL 216 A P +I A L Y P+ V++ Y+ + + Sbjct: 366 AVPLSLAITWAAAFLLTETGAYTYKGCDPNVPVSN--VVSTHCRKYMTRMKYCRVDTSHA 423 Query: 217 VKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISA-IAEAPITNKHI 275 + P P P WG+P FN + +++ ++SVG YHA S +A P T + Sbjct: 424 LSSAPWFRFPYPLQWGVPLFNWKMAFVMCVVSVIASVDSVGSYHASSLLVASRPPTRGVV 483 Query: 276 NRGIMSEGIACSIAGILGA-CGTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKF 334 +R I EG +AG+ G G+T+ +EN+ +A+TK+ SR VV++G +LV+ SL K Sbjct: 484 SRAIGLEGFTSVLAGLWGTGTGSTTLTENVHTIAVTKMGSRRVVELGACVLVIFSLVGKV 543 Query: 335 AGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVELNDRNTLILATSLIVGLGAP 390 G LAS+P ++ L ++ M + GL ++ + RN +I+ SL L P Sbjct: 544 GGFLASIPQVMVASLLCFMWAMFTALGLSNLRYSEAGSSRNIIIVGLSLFFSLSVP 599 >emb|CAB65186.1| (AJ012720) uracil permease [Lactobacillus plantarum] Length = 426 Score = 175 bits (439), Expect = 9e-43 Identities = 129/433 (29%), Positives = 227/433 (51%), Gaps = 39/433 (9%) Query: 7 VKVDEKVEPRKAILLGL--QHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGI 64 V +D P+ LGL QH+ +MFG+TV VP++VG G++ L + G+ Sbjct: 12 VVLDIHDRPKLGSWLGLSVQHLFSMFGSTVLVPILVGLNPGIA-----------LFSSGV 60 Query: 65 ATLLQTTIG-SRYPIVQGSSFAFIPGLISIGKSLGMAA-TEGALIVGGIIEALIGGTGIV 122 TL+ I + P GSSF+FI + S+ K+ G A +G + VG + + ++ Sbjct: 61 GTLMYILITRGKIPAYMGSSFSFIVVMQSLMKTAGYPAIAQGTVAVGCVYLLVSLLVTLI 120 Query: 123 GK--VKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATI-VALVTFITT 179 G + + P+V G +M+IG SLA A K A +GSS VA+ T + T Sbjct: 121 GSDWIDKALPPIVVGPIVMVIGLSLAGTAAKD-----ATMNGSSYDIKYFGVAMATMLLT 175 Query: 180 VYVALKAKGPIRAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPR---PFPWGIPEF 236 V + +G + +P++ G + GY+++V +G+ +F V++ ++P PF P Sbjct: 176 VIFNMYLRGFMSLVPILLGIVCGYIIAVLVGIVDFSGVEKAQWFAMPAFQLPFISYHPGI 235 Query: 237 NLTAIVTLLFAFMVSIIESVGDYHAISAIAEAPI-TNKHINRGIMSEGIACSIAGILGAC 295 AI+++ V++ E +G ++ + + N +N + +G A IAG +G Sbjct: 236 YWGAILSMAPIAFVTMSEHMGHIMVLNKLTKRNFFKNPGLNHTLAGDGTASIIAGFVGGP 295 Query: 296 GTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYG 355 TSY ENIG++A+T+V S YV+ +V S K + ++ S+P+PV+GG++ L+G Sbjct: 296 PVTSYGENIGVLAITRVHSIYVLGGAAFFAIVFSFVGKLSALIESIPSPVIGGVSFLLFG 355 Query: 356 MISVTGLR-LIKDKVELNDRNTLILATS-LIVGLGAPQLPPKFLAHFPRIVASILESGMA 413 +I+ +G+R LI +KV+ N + L++A++ L++G+G L + S SG+A Sbjct: 356 VIASSGMRILIDNKVDFNQKRNLMIASAILVIGIGNAYLQ----------LGSFQFSGLA 405 Query: 414 IGAITAIVLDQLL 426 + + IV++ +L Sbjct: 406 VATVLGIVMNLVL 418 >sp|P39766|PYRP_BACSU URACIL PERMEASE (URACIL TRANSPORTER) >gi|2127139|pir||A57986 membrane-bound uracil permease pyrP - Bacillus subtilis >gi|387578|gb|AAA21266.1| (M59757) putative membrane-bound uracil permease [Bacillus subtilis] >gi|2633921|emb|CAB13422.1| (Z99112) uracil permease [Bacillus subtilis] Length = 434 Score = 171 bits (428), Expect = 2e-41 Identities = 132/426 (30%), Positives = 219/426 (50%), Gaps = 37/426 (8%) Query: 15 PRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTTIGS 74 P + LQH+ AMFG+T+ VP +VG + ++ L+ GI TL I Sbjct: 16 PFSWVSFSLQHLFAMFGSTILVPKLVGMSPAVA-----------LVTSGIGTLAYLLITK 64 Query: 75 -RYPIVQGSSFAFIPGLISIGKSLGM-AATEGALIVG---GIIEALIGGTGIVGKVKRLF 129 + P GSSFAFI +I + + G AA GA + G G+I LI G G + ++ Sbjct: 65 GQIPAYLGSSFAFISPIILVKATGGPGAAMVGAFLAGLVYGLIALLIRQLG-TGWLMKIL 123 Query: 130 TPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRAT---IVALVTFITTVYVALKA 186 P+V G I++IG LA AV YADP+ S + + VA VT T+ A+ Sbjct: 124 PPVVVGPVIIVIGLGLASTAVN--MAMYADPNASELVYSLKHFSVAGVTLAITIICAIFL 181 Query: 187 KGPIRAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPR---PFPWGIPEFNLTAIVT 243 +G + +PV+ G + GYL ++ G+ NFQ V + ++P PF + +A Sbjct: 182 RGFLSLIPVLIGIIGGYLFALTQGIVNFQPVLDAKWFAVPEFIIPFKDYHRQLR-SASQP 240 Query: 244 LLFAFMVSIIESVGDYH-AISAIAEAPITNKHINRGIMSEGIACSIAGILGACGTTSYSE 302 F +S +S+ + A S + ++R IM + +A +A ++G TT+Y E Sbjct: 241 QWFLSHLSQCQSISATNGAESKVVGQDFIKAGLHRSIMGDSVATILASLIGGPPTTTYGE 300 Query: 303 NIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGL 362 NIG++A+T+V S +V+ +I + K + +++S+P+ V+GG++ L+G+I+ +GL Sbjct: 301 NIGVLAITRVFSVFVIGGAAVIALCFGFIGKISALISSVPSAVMGGVSFLLFGIIASSGL 360 Query: 363 R-LIKDKVEL-NDRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAITAI 420 R LI +K++ N+RN +I + L++G+G A SGMA+ AI + Sbjct: 361 RMLIDNKIDYENNRNLIITSVILVIGVGG--------AFIQVSQGGFQVSGMALAAIVGV 412 Query: 421 VLDQLL 426 +L+ +L Sbjct: 413 ILNLIL 418 >dbj|BAA94190.1| (AP000422) uracil transport protein [Escherichia coli O157:H7] Length = 442 Score = 170 bits (426), Expect = 3e-41 Identities = 129/440 (29%), Positives = 232/440 (52%), Gaps = 53/440 (12%) Query: 6 LVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIA 65 +V DE++ + ++G+QH +AMFGATV +P+++G LS +L GI Sbjct: 20 VVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLS-----------ILMSGIG 68 Query: 66 TLLQTTI-GSRYPIVQGSSFAFIPGLISI------GKSLGMAATEGALIVGGIIEALIGG 118 TLL I G R P GSS AF+ +I+ G + ++ G +I G++ +IG Sbjct: 69 TLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGL 128 Query: 119 TGI-VGK--VKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVT 175 + +G ++RL P+VTG +M IG +LA +AVK S S+ + +A++T Sbjct: 129 VVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVK---------SVSASGFDSWMAVMT 179 Query: 176 FITTVYVALKAKGPIRAMPVIAGALVGYLV----SVPLGLA---NFQLVKELPLVSLPRP 228 + VA+ +G I+ + ++ G +V L+ + LGL +F LV LP Sbjct: 180 VLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPH- 238 Query: 229 FPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEAPITNKHINRGIMSEGIACSI 288 + P FN A++ + ++ + E++G A++ + + + ++ R + +G+A + Sbjct: 239 --FSTPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNM-DPYMGRAFVGDGLATML 295 Query: 289 AGILGACGTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGG 348 +G +G+ G T+Y+ENIG++A+TKV S V +I ++L PKF ++ ++PA V+GG Sbjct: 296 SGSVGSSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGG 355 Query: 349 LTIALYGMISVTGLRL-IKDKVELNDRNTLIL-ATSLIVGLGAPQLPPKFLAHFPRIVAS 406 +I ++G+I+V G R+ ++++V+L+ LI+ A +L++G G F + Sbjct: 356 ASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAG----------DFALTLGG 405 Query: 407 ILESGMAIGAITAIVLDQLL 426 G+ AI+L+ LL Sbjct: 406 FTLGGIGTATFGAILLNALL 425 >sp|P75892|YCDG_ECOLI HYPOTHETICAL 48.1 KD PROTEIN IN WRBA-PUTA INTERGENIC REGION >gi|7446794|pir||D64842 probable transport protein ycdG - Escherichia coli >gi|1787241|gb|AAC74091.1| (AE000202) putative transport protein [Escherichia coli K12] Length = 464 Score = 170 bits (426), Expect = 3e-41 Identities = 129/440 (29%), Positives = 231/440 (52%), Gaps = 53/440 (12%) Query: 6 LVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIA 65 +V DE++ + ++G+QH +AMFGATV +P+++G LS +L GI Sbjct: 42 VVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLS-----------ILMSGIG 90 Query: 66 TLLQTTI-GSRYPIVQGSSFAFIPGLISI------GKSLGMAATEGALIVGGIIEALIGG 118 TLL I G R P GSS AF+ +I+ G + ++ G +I G++ +IG Sbjct: 91 TLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGL 150 Query: 119 TGI-VGK--VKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVT 175 + +G ++RL P+VTG +M IG +LA +AVK S S+ + +A++T Sbjct: 151 VVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVK---------SVSASAFDSWMAVMT 201 Query: 176 FITTVYVALKAKGPIRAMPVIAGALVGYLV----SVPLGLA---NFQLVKELPLVSLPRP 228 + VA+ +G I+ + ++ G +V L+ + LGL +F LV LP Sbjct: 202 VLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPH- 260 Query: 229 FPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEAPITNKHINRGIMSEGIACSI 288 + P FN A++ + ++ + E++G A++ + + + ++ R + +G+A + Sbjct: 261 --FSTPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNM-DPYMGRAFVGDGLATML 317 Query: 289 AGILGACGTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGG 348 +G +G G T+Y+ENIG++A+TKV S V +I ++L PKF ++ ++PA V+GG Sbjct: 318 SGSVGGSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGG 377 Query: 349 LTIALYGMISVTGLRL-IKDKVELNDRNTLIL-ATSLIVGLGAPQLPPKFLAHFPRIVAS 406 +I ++G+I+V G R+ ++++V+L+ LI+ A +L++G G F + Sbjct: 378 ASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAG----------DFALTLGG 427 Query: 407 ILESGMAIGAITAIVLDQLL 426 G+ AI+L+ LL Sbjct: 428 FTLGGIGTATFGAILLNALL 447 >dbj|BAA35773.1| (D90737) Uracil transport protein [Escherichia coli] >gi|4062569|dbj|BAA35783.1| (D90738) Uracil transport protein [Escherichia coli] Length = 442 Score = 170 bits (426), Expect = 3e-41 Identities = 129/440 (29%), Positives = 231/440 (52%), Gaps = 53/440 (12%) Query: 6 LVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIA 65 +V DE++ + ++G+QH +AMFGATV +P+++G LS +L GI Sbjct: 20 VVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLS-----------ILMSGIG 68 Query: 66 TLLQTTI-GSRYPIVQGSSFAFIPGLISI------GKSLGMAATEGALIVGGIIEALIGG 118 TLL I G R P GSS AF+ +I+ G + ++ G +I G++ +IG Sbjct: 69 TLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGL 128 Query: 119 TGI-VGK--VKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVT 175 + +G ++RL P+VTG +M IG +LA +AVK S S+ + +A++T Sbjct: 129 VVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVK---------SVSASAFDSWMAVMT 179 Query: 176 FITTVYVALKAKGPIRAMPVIAGALVGYLV----SVPLGLA---NFQLVKELPLVSLPRP 228 + VA+ +G I+ + ++ G +V L+ + LGL +F LV LP Sbjct: 180 VLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPH- 238 Query: 229 FPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEAPITNKHINRGIMSEGIACSI 288 + P FN A++ + ++ + E++G A++ + + + ++ R + +G+A + Sbjct: 239 --FSTPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNM-DPYMGRAFVGDGLATML 295 Query: 289 AGILGACGTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGG 348 +G +G G T+Y+ENIG++A+TKV S V +I ++L PKF ++ ++PA V+GG Sbjct: 296 SGSVGGSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGG 355 Query: 349 LTIALYGMISVTGLRL-IKDKVELNDRNTLIL-ATSLIVGLGAPQLPPKFLAHFPRIVAS 406 +I ++G+I+V G R+ ++++V+L+ LI+ A +L++G G F + Sbjct: 356 ASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAG----------DFALTLGG 405 Query: 407 ILESGMAIGAITAIVLDQLL 426 G+ AI+L+ LL Sbjct: 406 FTLGGIGTATFGAILLNALL 425 >sp|P33780|URAA_ECOLI URACIL PERMEASE (URACIL TRANSPORTER) >gi|1084126|pir||A56265 uracil transport protein uraA - Escherichia coli >gi|313777|emb|CAA51992.1| (X73586) uracil permease [Escherichia coli] >gi|1788843|gb|AAC75550.1| (AE000336) uracil transport [Escherichia coli K12] >gi|1805557|dbj|BAA16385.1| (D90878) uracil transport protein uraA [Escherichia coli] Length = 429 Score = 169 bits (423), Expect = 7e-41 Identities = 133/434 (30%), Positives = 215/434 (48%), Gaps = 36/434 (8%) Query: 7 VKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIAT 66 + V E+ + I L LQH+ AMFGATV VP++ I VLL GI T Sbjct: 6 IGVSERPPLLQTIPLSLQHLFAMFGATVLVPVL-----------FHINPATVLLFNGIGT 54 Query: 67 LLQTTI-GSRYPIVQGSSFAFIPGLISIGKSLGMAATEGALIVGGIIEALIG------GT 119 LL I + P GSSFAFI ++ + LG G I+ G++ L+ GT Sbjct: 55 LLYLFICKGKIPAYLGSSFAFISPVLLL-LPLGYEVALGGFIMCGVLFCLVSFIVKKAGT 113 Query: 120 GIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITT 179 G + LF P G + +IG LA VA A+ + I+++ T T Sbjct: 114 GWLDV---LFPPAAMGAIVAVIGLELAGVAAGMAGLLPAEGQTPD-SKTIIISITTLAVT 169 Query: 180 VYVALKAKGPIRAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLT 239 V ++ +G + +P++ G LVGY +S +G+ + + +LP + P F Sbjct: 170 VLGSVLFRGFLAIIPILIGVLVGYALSFAMGIVDTTPIINAHWFALPTLYT---PRFEWF 226 Query: 240 AIVTLLFAFMVSIIESVGDYHAISAIAEAPIT-NKHINRGIMSEGIACSIAGILGACGTT 298 AI+T+L A +V I E VG + I + + + ++R + + G++ I+G G+ T Sbjct: 227 AILTILPAALVVIAEHVGHLVVTANIVKKDLLRDPGLHRSMFANGLSTVISGFFGSTPNT 286 Query: 299 SYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMIS 358 +Y ENIG++A+T+V S +V+ I ++LS K A + +P PV+GG+++ LYG+I Sbjct: 287 TYGENIGVMAITRVYSTWVIGGAAIFAILLSCVGKLAAAIQMIPLPVMGGVSLLLYGVIG 346 Query: 359 VTGLR-LIKDKVELNDRNTLILATSLI--------VGLGAPQLPPKFLAHFPRIVASILE 409 +G+R LI+ KV+ N LIL + ++ V +GA +L LA I S++ Sbjct: 347 ASGIRVLIESKVDYNKAQNLILTSVILIIGVSGAKVNIGAAELKGMALATIVGIGLSLIF 406 Query: 410 SGMAIGAITAIVLD 423 +++ +VLD Sbjct: 407 KLISVLRPEEVVLD 420 >gb|AAD14479.1| (AC005966) Strong similarity to gi|3337350 F13P17.3 putative permease from Arabidopsis thaliana BAC gb|AC004481 Length = 543 Score = 168 bits (421), Expect = 1e-40 Identities = 127/414 (30%), Positives = 196/414 (46%), Gaps = 45/414 (10%) Query: 17 KAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTTIGSRY 76 +AILLG QH L M G TV +P + +G EE + M+Q +L G+ TLLQ+ G+R Sbjct: 44 EAILLGFQHYLVMLGTTVLIPTYLVPQMGGGNEEKAKMVQTLLFVSGLNTLLQSFFGTRL 103 Query: 77 PIVQGSSFAFIPGLISI---GKSLG----------------MAATEGALIVGGIIEALIG 117 P V G S+ ++P +SI G+ M +GALIV I++ ++G Sbjct: 104 PAVIGGSYTYVPTTLSIILAGRYSDILDPQESENMQKFKRIMRGIQGALIVASILQIVVG 163 Query: 118 GTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFI 177 +G+ V RL +PL + L GF L + + F A +P I+ L+ F Sbjct: 164 FSGLWRNVVRLLSPLSAVPLVALAGFGLYE----HGFPLLAKCIEIGLPE--IILLLLFS 217 Query: 178 TTVYVALKAKGPI-RAMPVIAGALVGYLVSVPLGLA--------NFQ---------LVKE 219 + ++ + + VI ++ ++ + L + N Q L+ Sbjct: 218 QYIPHLIRGERQVFHRFAVIFSVVIVWIYAHLLTVGGAYKNTGVNTQTSCRTDRSGLISG 277 Query: 220 LPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEA-PITNKHINRG 278 P + +P PF WG P F+ ++ VS+IES G Y +S A A P ++RG Sbjct: 278 SPWIRVPYPFQWGPPTFHAGEAFAMMAVSFVSLIESTGTYIVVSRFASATPPPPSVLSRG 337 Query: 279 IMSEGIACSIAGILGACGTTSYS-ENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGI 337 + +G+ + G+ GA S S EN GL+ALT+V SR VVQI ++ S+ KF I Sbjct: 338 VGWQGVGVLLCGLFGAGNGASVSVENAGLLALTRVGSRRVVQISAGFMIFFSILGKFGAI 397 Query: 338 LASMPAPVLGGLTIALYGMISVTGLRLIKDKVELNDRNTLILATSLIVGLGAPQ 391 AS+PAPV+ L + + GL L++ + R IL S+ +GL PQ Sbjct: 398 FASIPAPVVAALHCLFFAYVGAGGLSLLQFCNLNSFRTKFILGFSVFMGLSIPQ 451 >dbj|BAB08803.1| (AB024032) permease [Arabidopsis thaliana] Length = 483 Score = 163 bits (408), Expect = 4e-39 Identities = 121/397 (30%), Positives = 191/397 (47%), Gaps = 40/397 (10%) Query: 29 MFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTTIGSRYPIVQGSSFAFIP 88 M G TV +P + +G EE + +IQ +L G+ TLLQT G+R P V G+S+ F+P Sbjct: 1 MLGTTVLIPSALVPQMGGRNEEKAKLIQTILFVAGLNTLLQTVFGTRLPAVIGASYTFVP 60 Query: 89 GLISI---GKSLGMA-----------ATEGALIVGGIIEALIGGTGIVGKVKRLFTPLVT 134 ISI G+ +A AT+GALIV ++ ++G +G+ V R +PL Sbjct: 61 VTISIMLSGRFNDVADPVERFKRIIRATQGALIVASTLQIILGFSGLWRNVVRFLSPLSA 120 Query: 135 GVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITTVYVALKAKGPIRAMP 194 + L+G+ L ++ F A +P I+ L++ +V K Sbjct: 121 APLVGLVGYGLYELG----FPGVAKCIEIGLPGLIILILISQYMP-HVIKGGKHVFARFA 175 Query: 195 VIAGALVGYLVSVPLGLANFQ-----------------LVKELPLVSLPRPFPWGIPEFN 237 VI + +L + L L L+ P + +P PF WG P F+ Sbjct: 176 VIFSVAIVWLYAFFLTLGGAYNGVGTDTQRSCRTDRAGLISAAPWIRVPWPFQWGAPLFD 235 Query: 238 LTAIVTLLFAFMVSIIESVGDYHAISAIAEAPITNKH-INRGIMSEGIACSIAGILGA-C 295 ++ A V+++ES G + A+S A A + I+RG+ +G+A I+G+ G Sbjct: 236 AGEAFAMMMASFVALVESTGAFIAVSRYASATMPPPSVISRGVGWQGVAILISGLFGTGI 295 Query: 296 GTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYG 355 G++ EN GL+ALTK+ SR VVQI ++ S+ KF + AS+P+P++ L + Sbjct: 296 GSSVSVENAGLLALTKIGSRRVVQISAGFMIFFSILGKFGAVFASIPSPIIAALYCLFFA 355 Query: 356 MISVTGLRLIKDKVELNDRNTL-ILATSLIVGLGAPQ 391 + GL L++ LN TL IL S+ +GL PQ Sbjct: 356 YVGAGGLSLLQ-FCNLNSFRTLFILGFSIFLGLSIPQ 391 >pir||T24671 hypothetical protein T07G12.5 - Caenorhabditis elegans >gi|3879626|emb|CAB05270.1| (Z82282) predicted using Genefinder~Similarity to Bacillus xanthine permease (SW:P42086), contains similarity to Pfam domain: PF00860 (Xanthine/uracil permeases family), Score=617.3, E-value=2.8e-182, N=1~cDNA EST yk239b5.3 comes from this gene~cDNA ES> Length = 555 Score = 162 bits (407), Expect = 5e-39 Identities = 127/492 (25%), Positives = 226/492 (45%), Gaps = 94/492 (19%) Query: 4 GVLVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQ---AVLL 60 G+ V+E P +L GLQ ++ + + +P VV + + + I +Q A + Sbjct: 3 GLHFHVNEIPSPPSIMLFGLQQMMICLSSLLVIPYVVSDMLCAGDQAMEIRVQLISATFV 62 Query: 61 AMGIATLLQTTIGSRYPIVQGSSFAFIPGLISIGKSLG-------------MAATEGALI 107 GIAT+LQTT G R I+ G SFAF+P L + + M G+ + Sbjct: 63 TSGIATILQTTFGMRLSILHGPSFAFLPALHTFQATFPCDANTDTSNWQEKMQMISGSCL 122 Query: 108 VGGIIEALIGGTGIVGKVKRLFTP--LVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSI 165 + +I ++G TG+VGK+ + P +V ++++ IG ++ D+ K ++ + Sbjct: 123 IAVLIMPILGFTGLVGKISKYIGPVTIVPIMSLLTIG-TVPDIESKMALHWIS------- 174 Query: 166 PRATIVALVTFITTVYVALKAKGPI------------------RAMPVIAGALVGYLVSV 207 IV +T I V + + + PI P + G + + + Sbjct: 175 ----IVEFLTLILFVVILERYEVPIPIFSLSEKKFKFTRQKIFSQFPYLLGISIVWFICF 230 Query: 208 PLGLANFQ---------------LVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVSI 252 + + N + + + P V +P P +G P+FNL + + ++ Sbjct: 231 IMTITNAEPRGGEARTDQNASITVFDQTPWVQMPMPLFFGPPKFNLALVCGFTASCFAAM 290 Query: 253 IESVGDYHAISAIAEA---PITNKHINRGIMSEGIACSIAGILGA-CGTTSYSENIGLVA 308 IES+GDY+ + I++ P +N NR + EGI C +A + G G T+Y+ENI +++ Sbjct: 291 IESIGDYNLCAKISKQSRPPPSNT--NRAFVVEGIGCILAALWGVGTGVTTYAENIAIMS 348 Query: 309 LTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLT---IALYGMISVTGLRLI 365 +TKV SR +Q+ G+ L++ + KFA L+ +P P++GGL + L +S++ L+ + Sbjct: 349 VTKVTSRITMQMAGVFLILAGVISKFAAFLSMIPEPIIGGLLAMGVCLINGVSLSNLQTV 408 Query: 366 KDKVELNDRNTLILATSLIVGLGAPQLPPKFLAHFPR------------IVASILESGMA 413 K+ RN I+ S+I+GL HF + + ++L M Sbjct: 409 DMKL---SRNLTIIGVSIIMGL-------TVATHFEKTPLNTGNQIVDDVFGTLLTIRML 458 Query: 414 IGAITAIVLDQL 425 IG + A VLD + Sbjct: 459 IGGVIAFVLDNI 470 >gb|AAF76447.1|AC015445_14 (AC015445) Identical to permease homolog (At PER-X) partial cds gb|U83501 and contains a Xanthine/Uracil Permease PF|00860 domain. EST gb|AA712474 comes from this gene. [Arabidopsis thaliana] Length = 529 Score = 162 bits (405), Expect = 9e-39 Identities = 133/474 (28%), Positives = 207/474 (43%), Gaps = 63/474 (13%) Query: 3 PGVLVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAM 62 PGV V P I+LG QH + M G TV +P ++ +G E + +I VL Sbjct: 18 PGVEFCVSSS--PNWRIVLGFQHYIVMLGTTVIIPSILVPLMGGGDVEKAEVINTVLFVS 75 Query: 63 GIATLLQTTIGSRYPIVQGSSFAFIPGLISIGKSLG--------------MAATEGALIV 108 GI TLLQ+ GSR P+V G+S+A++ + I S M A +GALI+ Sbjct: 76 GINTLLQSLFGSRLPVVMGASYAYLIPALYITFSYRFTYYLHPHLRFEETMRAIQGALII 135 Query: 109 GGIIEALIGGTGIVGKVKRLFTPL-------VTGVTIMLIGFS----------------- 144 I ++G G+ + R +PL +TGV ++ F Sbjct: 136 ASISHMIMGFFGLWRILVRFLSPLSAAPLVILTGVGLLAFAFPQLARCIEIGLPALIILI 195 Query: 145 -LADVAVKYFFNFYADPSGSSIPRATIVALVTFITTVYVALKAKGPIRAMPVIAGALVGY 203 L+ V+V ++ S + ++ + + L A G P Sbjct: 196 ILSQVSVNFYLPHLFKCKRSICEQFAVLFTIAIVWAYAEILTAAGAYDKRPDNT------ 249 Query: 204 LVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAIS 263 + L+ P V +P P WG P F+ + ++ A V+I+E+ G + A S Sbjct: 250 --QLSCRTDRSGLISASPWVRIPYPLQWGRPSFHGSDAFAMMAATYVAIVETTGSFIAAS 307 Query: 264 AIAEAP-ITNKHINRGIMSEGIACSIAGILG-ACGTTSYSENIGLVALTKVASRYVVQIG 321 A I ++RGI +GI + G+ G A G+T+ EN GL+ LTKV SR VVQI Sbjct: 308 RFGSATHIPPSVLSRGIGWQGIGVLLNGLFGTATGSTALVENTGLLGLTKVGSRRVVQIS 367 Query: 322 GIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVELNDRNTLILAT 381 ++ S+F KF +LAS+P P+ L L+ ++ GL L++ + RN IL Sbjct: 368 AGFMIFFSIFGKFGAVLASIPLPIFAALYCVLFAYVASAGLGLLQFCNLNSFRNKFILGF 427 Query: 382 SLIVGLGAPQLPPKFL------------AHFPRIVASILESGMAIGAITAIVLD 423 S+ +GL Q ++L + F I+ I S +G + A +LD Sbjct: 428 SIFIGLSVAQYFTEYLFISGRGPVHTRTSAFNVIMQVIFSSAATVGIMAAFLLD 481 >gb|AAD30433.1|AF118561_1 (AF118561) sodium-coupled ascorbic acid transporter SVCT2 [Oryctolagus cuniculus] Length = 412 Score = 161 bits (404), Expect = 1e-38 Identities = 126/403 (31%), Positives = 190/403 (46%), Gaps = 79/403 (19%) Query: 66 TLLQTTIGSRYPIVQGSSFAFIP---GLISIGK--------SLGMAATE----------- 103 TLLQTT G R P+ Q S+FAF+ ++S+ K S+ E Sbjct: 1 TLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTDVSIANGTAELLHTEHIWYPR 60 Query: 104 -----GALIVGGIIEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYA 158 GA+I+ +IE IG G+ G + R PL T+ LIG S F Sbjct: 61 IREIQGAIIMSSLIEVFIGLLGLPGALLRYIGPLTITPTVALIGLS--------GFQAAG 112 Query: 159 DPSGSSIPRATIVALVTFITTVYVALKAKGPI-----------------RAMPVIAGALV 201 + +G A + + + + Y A K P+ + P+I LV Sbjct: 113 ERAGKHWGIAMLTIFLVLLFSQY-ARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILV 171 Query: 202 GYLV-------------SVPLGL-----ANFQLVKELPLVSLPRPFPWGIPEFNLTAIVT 243 +L+ S G A ++ P +P PF WG+P + ++ Sbjct: 172 SWLLCFIFTVTDVFPPDSTKYGSYARTDARQGVLLVAPWFKVPYPFQWGLPTVSAAGVIG 231 Query: 244 LLFAFMVSIIESVGDYHAISAIAEAPITNKH-INRGIMSEGIACSIAGILGAC-GTTSYS 301 +L A + SIIES+GDY+A + ++ AP H INRGI EG++C + GI G G+TS S Sbjct: 232 MLSAVVASIIESIGDYYACAWLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSS 291 Query: 302 ENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTG 361 NIG++ +TKV SR V+Q G +++ L + KF+ + AS+P PVLG L L+GMI+ G Sbjct: 292 PNIGVLGITKVGSRRVIQYGAALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVG 351 Query: 362 LRLIKDKVELN-DRNTLILATSLIVGLGAPQLPPKFLAHFPRI 403 L ++ ++LN RN +L S+ GL +PP +L P + Sbjct: 352 LSNLQ-FIDLNSSRNLFVLGFSIFFGL----VPPSYLRQNPLV 389 >gb|AAD26910.1|AC007233_2 (AC007233) putative membrane transporter [Arabidopsis thaliana] Length = 520 Score = 161 bits (402), Expect = 2e-38 Identities = 126/459 (27%), Positives = 201/459 (43%), Gaps = 57/459 (12%) Query: 17 KAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTTIGSRY 76 + +LL Q+ + M G + +P ++ A+G S + + +IQ +L GI TLLQ G+R Sbjct: 27 ETVLLAFQNYILMLGTSAFIPALLVPAMGGSDGDRARVIQTLLFVAGIKTLLQALFGTRL 86 Query: 77 PIVQGSSFAFIPGLISIGKSLG--------------MAATEGALIVGGIIEALIGGTGIV 122 P V G S A++ + I M A +GALIV I+ ++G + + Sbjct: 87 PAVVGGSLAYVVPIAYIINDSSLQKISNDHERFIHTMRAIQGALIVASSIQIILGYSQVW 146 Query: 123 GKVKRLFTPLVTGVTIMLIGFSLADVA---------------------VKYFFNFYADPS 161 G R F+PL + L+G + +Y + Sbjct: 147 GLFSRFFSPLGMAPVVGLVGLGMFQRGFPQLGNCIEIGLPMLLLVIGLTQYLKHVRPFKD 206 Query: 162 GSSIPRATIVALVTFITTVYVALKAKGPIRAMPVIAGALVGYLVSVPLGLANFQLVKELP 221 R I+ VT + V L A G R P + S AN L+ P Sbjct: 207 VPIFERFPILICVTIVWIYAVILTASGAYRGKPSLTQH------SCRTDKAN--LISTAP 258 Query: 222 LVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEA-PITNKHINRGIM 280 P P WG P F++ ++ A +VS++ES G Y A S +A A P ++RGI Sbjct: 259 WFKFPYPLQWGPPTFSVGHSFAMMSAVLVSMVESTGAYIAASRLAIATPPPAYVLSRGIG 318 Query: 281 SEGIACSIAGILGA-CGTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILA 339 +GI + G+ G G+T EN+GL+ LT+V SR VVQ+ ++V S KF + A Sbjct: 319 WQGIGVLLDGLFGTGTGSTVLVENVGLLGLTRVGSRRVVQVSAGFMIVFSTLGKFGAVFA 378 Query: 340 SMPAPVLGGLTIALYGMISVTGLRLIKDKVELNDRNTLILATSLIVGLGAPQLPPKF--- 396 S+P P+ L L+G+++ GL ++ + RN +I SL +G+ PQ ++ Sbjct: 379 SIPVPIYAALHCILFGLVAAVGLSFLQFTNMNSMRNLMITGLSLFLGISIPQFFAQYWDA 438 Query: 397 ----LAH-----FPRIVASILESGMAIGAITAIVLDQLL 426 L H F + ++ S +G I A+ +D + Sbjct: 439 RHYGLVHTNAGWFNAFLNTLFMSPATVGLIIAVFMDNTM 477 >gb|AAC12928.1| (AF044978) putative uracil permease [Enterococcus faecalis] Length = 419 Score = 161 bits (402), Expect = 2e-38 Identities = 119/426 (27%), Positives = 210/426 (48%), Gaps = 55/426 (12%) Query: 21 LGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQT-TIGSRYPIV 79 L LQH+ MFGATV VP++VG G++ L++ G+ T++ T + P Sbjct: 20 LSLQHLFTMFGATVLVPILVGIDPGIA-----------LVSSGLGTMVYLITTKGKIPAY 68 Query: 80 QGSSFAFIPGLISIGKSLGMAATEGALIVGGIIEALIGGTGIVGKV-----KRLFTPLVT 134 GSSFAFI + + KS G A + G++ ++ + I+ K+ ++ P+V Sbjct: 69 LGSSFAFIAAMQMLMKSDGYPAIAQGAMTTGLVYLIV--SLIIKKIGSDWLDKILPPIVV 126 Query: 135 GVTIMLIGFSLADVAVK--------YFFNFYADPSGSSIPRATIVALVTFITTVYVALKA 186 G +M+IG LA A Y F + A VAL+T T++ + Sbjct: 127 GPVVMVIGLGLAANAANNAMYNNNVYDFKYIA------------VALITLGLTIFYNMFF 174 Query: 187 KGPIRAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPR---PFPWGIPEFNLTAIVT 243 KG + +P++ G + GYLV++ G+ + +KE +LP PF P+ L AI T Sbjct: 175 KGFLGLIPILLGIVSGYLVALTFGIIDLTPIKEAAWFALPNFEVPFVQYEPKLYLNAITT 234 Query: 244 LLFAFMVSIIESVGDYHAISAIAEAPI-TNKHINRGIMSEGIACSIAGILGACGTTSYSE 302 + V++ E +G ++ + + + +++ +M G++ + +G TSY E Sbjct: 235 MAPIAFVTMTEHIGHLMVLNKLTKRNFFQDPGLSKTLMGHGLSQIVPRFVGGPPVTSYGE 294 Query: 303 NIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGL 362 NIG++A+T+V S +V+ + V L K ++ S+P PV+ G++ L+G+I+ +GL Sbjct: 295 NIGVLAITRVHSVFVIGGPAVFAVALGFVGKLHALILSIPGPVISGISFVLFGVIAASGL 354 Query: 363 R-LIKDKVELN-DRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAITAI 420 + LI +K+ + +N LI + L++G+G V + S MA+ + I Sbjct: 355 KILIDNKINFDKKKNLLIASVILVIGIGGLVFK----------VGTFELSSMALATVLGI 404 Query: 421 VLDQLL 426 VL+ +L Sbjct: 405 VLNLIL 410 >pir||T12309 permease 1 - common ice plant >gi|3202038|gb|AAC19400.1| (AF069322) permease 1 [Mesembryanthemum crystallinum] Length = 528 Score = 159 bits (399), Expect = 4e-38 Identities = 129/468 (27%), Positives = 209/468 (44%), Gaps = 48/468 (10%) Query: 3 PGVLVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAM 62 PGV ++ +AI LG QH L M G T+ +P ++ +G EE +++IQ +L Sbjct: 20 PGVDFCLNSNPPWHEAIALGFQHFLVMLGTTIMIPTILVPQMGGGPEEKALVIQTLLFVS 79 Query: 63 GIATLLQTTIGSRYPIVQGSSFAFIPGLISIGKS--------------LGMAATEGALIV 108 G+ TLLQT IG R +V G S AFI ISI S + M A +GA++ Sbjct: 80 GLNTLLQTMIGCRSSVVIGGSHAFIIPAISIIFSDQYGRIVDPYERFRVTMRAIQGAIMF 139 Query: 109 GGIIEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRA 168 ++ L+G G+ V R +PL ++L G L ++ F A +P Sbjct: 140 ASMLPVLVGVLGLWRIVVRFLSPLAAIPLVILTGLGL----FQFGFPQLAKCVEVGLPAL 195 Query: 169 TIVALVT-FITTVYVALKAKGPIRAMPVIAGALVGY-LVSVPLGLANFQ----------- 215 ++ ++ + + + + G A+ +I G L + + G N Sbjct: 196 IVLVFISQYFSQLLKPFQVIGRRYAVILIVGLLWAFAAILTAAGAFNHSAPKTQFYCRTD 255 Query: 216 ---LVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEA-PIT 271 L+ + +P PF WG P N+ ++ A V+++ES G + + A P+ Sbjct: 256 RSGLISAAAWIRVPYPFQWGRPTLNVGNGFAMMAAAFVALVESTGTFITAARYGSATPLP 315 Query: 272 NKHINRGIMSEGIACSIAGILGA-CGTTSYSENIGLVALTKVASRYVVQIGGIILVVLSL 330 ++RG+ G+A I G+ GA G T+ EN GL+ L +V SR V Q+ + ++ S+ Sbjct: 316 PSVVSRGVSWLGVANFINGLFGAITGATASVENAGLLGLNQVGSRRVAQLSAVFMLFFSV 375 Query: 331 FPKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVELNDRNTLILATSLIVGLGAP 390 KF +LAS+P P+ L L+ + GL ++ + R+ IL SL +GL P Sbjct: 376 LGKFGALLASIPLPIFAALYCVLFAYAASAGLSFLQFCNLNSFRSKFILGFSLFMGLSIP 435 Query: 391 QLPPKFL------------AHFPRIVASILESGMAIGAITAIVLDQLL 426 Q +FL F ++ I S + I A+ LD L Sbjct: 436 QYFNEFLLVTGRTPVFTRSVAFNSMLQVIFSSPATVAGIIALFLDLTL 483 >gb|AAB17501.2| (U43034) permease 1 [Zea mays] Length = 527 Score = 159 bits (397), Expect = 8e-38 Identities = 123/410 (30%), Positives = 186/410 (45%), Gaps = 46/410 (11%) Query: 19 ILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTTIGSRYPI 78 +L+G QH L M G TV + ++ +G E +I+IQ +L GI TLLQ G+R P Sbjct: 35 VLVGFQHYLVMLGTTVLIATIIVPLMGGGHAEKAIVIQTILFLSGINTLLQVHFGTRLPA 94 Query: 79 VQGSSFAFIPGLISIGKS--------------LGMAATEGALIVGGIIEALIGGTGIVGK 124 V S+ +I ++I S M + +GALI+ G+ +A++G GI Sbjct: 95 VMSGSYTYIYPAVAIILSPRYALLIDPLERFVFTMRSLQGALIIAGVFQAVVGFFGIWRV 154 Query: 125 VKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITTVYVA- 183 R +PL + L G L +FF F + +V LV F Y + Sbjct: 155 FIRFLSPLAAVPFVTLTGLGL------FFFAFPGVTKCIEVGLPALVLLVIFAE--YASH 206 Query: 184 LKAKGPI---RAMPVIAGALVGYLVSVPLGLANFQ----------------LVKELPLVS 224 L AKG R ++ ++ + + +++ P V Sbjct: 207 LFAKGSFVFSRCAVLVTVVIIWIYAEILTAAGAYNERGPVTQFSCRADRSGIIQGSPWVR 266 Query: 225 LPRPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEAPITNKHI-NRGIMSEG 283 P PF WG P F +L A S+IES G A+S + A + +RGI EG Sbjct: 267 FPYPFQWGYPIFCFQDCFAMLAASFASLIESTGTLIAVSRYSGATFCPPSVFSRGIGWEG 326 Query: 284 IACSIAGILGAC-GTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMP 342 I+ + G+ G GT + EN GL+A+T+V SR V++I + ++ SLF KF +LAS+P Sbjct: 327 ISIILDGMCGTLTGTAASVENAGLLAVTRVGSRRVIKISALFMIFFSLFAKFGAVLASIP 386 Query: 343 APVLGGLTIALYGMISVTGLRLIKDKVELND-RNTLILATSLIVGLGAPQ 391 P+ L L+ + G L++ LN R IL+ SL +GL PQ Sbjct: 387 LPIFAALYCVLFAYSAGAGFSLLQ-YCNLNSLRTKFILSISLFLGLSIPQ 435 >pir||T33745 hypothetical protein R11E3.2 - Caenorhabditis elegans >gi|3800987|gb|AAC68987.1| (AF100669) contains similarity to xanthine/uracil permeases family [Caenorhabditis elegans] Length = 546 Score = 158 bits (395), Expect = 1e-37 Identities = 119/465 (25%), Positives = 214/465 (45%), Gaps = 70/465 (15%) Query: 19 ILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAV---LLAMGIATLLQTTIGSR 75 +L+G Q ++ + +P ++ V +E I +Q + + GIAT+LQTT G R Sbjct: 23 LLIGFQQMMICISMLLVIPYMMSDMVCPGDKETEIRVQLISASFVTAGIATILQTTFGMR 82 Query: 76 YPIVQGSSFAFIPGLISIGKSLG-------------MAATEGALIVGGIIEALIGGTGIV 122 I+ G SFA++P L + + M G+ +V ++ L G TG++ Sbjct: 83 LAILHGPSFAYLPVLNTFQSTYPCNEHTDTSLWQHKMQMISGSCLVAVLVMPLFGFTGLI 142 Query: 123 GKVKRLFTPL-VTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITTVY 181 G + + P+ + + +L +++DV K ++ SS+ +V + + Sbjct: 143 GFLSQFIGPITIVPIMTLLTISAVSDVEQKMALHWM-----SSVEFLMLVVFIVLLEHWE 197 Query: 182 VALKA------------KGPIRAMPVIAGALVGYLVSVPLGLAN---------------F 214 + L A + + P I G +G+L+ L + N Sbjct: 198 MPLPAYSLKRRHFYIARRKILSQFPYIIGIAIGWLICYILTVTNAIPANSPARTDQNSTM 257 Query: 215 QLVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIA-EAPITNK 273 +++K P V +P P +G P +++ + + + V++IES+GDY+ + ++ + I Sbjct: 258 EILKSTPWVHVPIPGQYGTPIIDISLLCGFIASSFVAMIESIGDYNLCAKLSKQGRIPTS 317 Query: 274 HINRGIMSEGIACSIAGILG-ACGTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFP 332 ++NRG + EGI C ++ G G T+Y+ENI ++++TKVASR +Q GI L++ +F Sbjct: 318 NLNRGFIVEGIGCMLSSSFGIGTGITTYAENIAIMSVTKVASRITMQTAGIFLLIAGIFS 377 Query: 333 KFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVELNDRNTLILATSLIVGLGAPQL 392 KFA +LA +P PV+GG+ M++ LR + RN I+ ++I+GL Sbjct: 378 KFAAVLAMIPEPVVGGVLAIGICMVNGVVLRNLMTVDLRLSRNLTIMGIAVIMGL----- 432 Query: 393 PPKFLAHF------------PRIVASILESGMAIGAITAIVLDQL 425 HF + ++L M IG I A LD + Sbjct: 433 --TVALHFENNPLKTGNQTVDNVFGTLLTIRMLIGGIIAFTLDNI 475 >pir||T12313 permease 1 - common ice plant >gi|3202040|gb|AAC19401.1| (AF069323) permease 1 [Mesembryanthemum crystallinum] Length = 526 Score = 155 bits (389), Expect = 7e-37 Identities = 127/467 (27%), Positives = 208/467 (44%), Gaps = 48/467 (10%) Query: 3 PGVLVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAM 62 PGV ++ +AI LG QH L M G T+ +P ++ +G EE +++IQ +L Sbjct: 20 PGVDFCLNSNPPWHEAIALGFQHFLVMLGTTIMIPTILVPQMGGGPEEKALVIQTLLFVS 79 Query: 63 GIATLLQTTIGSRYPIVQGSSFAFIPGLISIGKS--------------LGMAATEGALIV 108 G+ TLLQT IG R +V G S AFI ISI S + M A +GA++ Sbjct: 80 GLNTLLQTMIGCRSSVVIGGSHAFIIPAISIIFSDQYGRIVDPYERFRVTMRAIQGAIMF 139 Query: 109 GGIIEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRA 168 ++ L+G G+ V R +PL ++L G L ++ F A +P Sbjct: 140 ASMLPVLVGVLGLWRIVVRFLSPLAAIPLVILTGLGL----FQFGFPQLAKCVEVGLPAL 195 Query: 169 TIVALVT-FITTVYVALKAKGPIRAMPVIAGALVGY-LVSVPLGLANFQ----------- 215 ++ ++ + + + + G A+ +I G L + + G N Sbjct: 196 IVLVFISQYFSQLLKPFQVIGRRYAVILIVGLLWAFAAILTAAGAFNHSAPKTQFYCRTD 255 Query: 216 ---LVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEA-PIT 271 L+ + +P PF WG P N+ ++ A V+++ES G + + A P+ Sbjct: 256 RSGLISAAAWIRVPYPFQWGRPTLNVGNGFAMMAAAFVALVESTGTFITAARYGSATPLP 315 Query: 272 NKHINRGIMSEGIACSIAGILGACGTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLF 331 ++RG+ G+A I G+ GA T + + N GL+ L +V SR V Q+ + ++ S+ Sbjct: 316 PSVVSRGVSWLGVANFINGLFGAI-TGATASNAGLLGLNQVGSRRVAQLSAVFMLFFSVL 374 Query: 332 PKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVELNDRNTLILATSLIVGLGAPQ 391 KF +LAS+P P+ L L+ + GL ++ + R+ IL SL +GL PQ Sbjct: 375 GKFGALLASIPLPIFAALYCVLFAYAASAGLSFLQFCNLNSFRSKFILGFSLFMGLSIPQ 434 Query: 392 LPPKFL------------AHFPRIVASILESGMAIGAITAIVLDQLL 426 +FL F ++ I S + I A+ LD L Sbjct: 435 YFNEFLLVTGRTPVFTRSVAFNSMLQVIFSSPATVAGIIALFLDLTL 481 >pir||D81844 uracil permease NMA1528 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7380170|emb|CAB84756.1| (AL162756) uracil permease [Neisseria meningitidis Z2491] Length = 403 Score = 155 bits (388), Expect = 9e-37 Identities = 120/418 (28%), Positives = 202/418 (47%), Gaps = 33/418 (7%) Query: 17 KAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLL-QTTIGSR 75 K + G Q + FGA V VPL+ G L+ LL G+ TLL Q T + Sbjct: 5 KLAVSGAQILFVAFGAMVLVPLLTGLNPALA-----------LLGAGLGTLLFQITTKRK 53 Query: 76 YPIVQGSSFAFIPGLISIGKSLGMAATEGALIVGG----IIEALIGGTGIVGKVKRLFTP 131 PI GSSFAFI +I G+ +T L G + ALI G+ V +L P Sbjct: 54 VPIFLGSSFAFIAPIIYSVGEWGLPSTMFGLFAAGFMYFVFAALIRWRGLAA-VHKLLPP 112 Query: 132 LVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITTVYVALKAKGPIR 191 +V G IM+IG S+A A + I++ TF T V++ ++ Sbjct: 113 VVIGPVIMVIGLSVAVAASSMAMGQADGKQVIDYTDSLILSGFTFAVTAIVSVFGSRMMK 172 Query: 192 AMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVS 251 +P++ G GY++++ +GL + + P ++P + P+ N A + +L + Sbjct: 173 LIPILIGVASGYVLALLMGLVDTASIAHAPWFAVPH---FETPQINWQAALFMLPVAVAP 229 Query: 252 IIESVGDYHAISAIAEAPIT-NKHINRGIMSEGIACSIAGILGACGTTSYSENIGLVALT 310 IE +G AI + E T + +++ + +G+ +AG++G T+Y E G V +T Sbjct: 230 AIEHIGGIMAIGNVTEKDYTKDPGLDKTLAGDGLGVCVAGLIGGPPVTTYGEVTGAVMIT 289 Query: 311 KVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLR-LIKDKV 369 K ++ ++ + V ++ F KF LAS+P PV+GG+ + L+G I+ G++ LI KV Sbjct: 290 KNSNPVIMTWAAVFAVCMAFFGKFNAFLASIPMPVMGGIMLLLFGTIASLGIKTLIDAKV 349 Query: 370 ELN-DRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAITAIVLDQLL 426 +L +N +I+++ L G+G L + S +G+ + A+ AI+L+ LL Sbjct: 350 DLMLPKNLVIVSSVLTTGIGGMTLK----------LGSFSFAGVGLCAVLAIMLNSLL 397 >pir||T00984 permease homolog T9J22.18 - Arabidopsis thaliana >gi|2739376|gb|AAC14499.1| (AC002505) putative membrane transporter [Arabidopsis thaliana] Length = 551 Score = 155 bits (387), Expect = 1e-36 Identities = 121/457 (26%), Positives = 202/457 (43%), Gaps = 54/457 (11%) Query: 17 KAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTTIGSRY 76 + ++L QH + M G TV + + + +G + + +IQ +L GI TLLQT IG+R Sbjct: 56 ETVVLAFQHYIVMLGTTVLIANTLVSPMGGDPGDKARVIQTILFMSGINTLLQTLIGTRL 115 Query: 77 PIVQGSSFAFIPGLISIGKSLG--------------MAATEGALIVGGIIEALIGGTGIV 122 P V G SFA++ ++SI + M +G+LI+ + +IG Sbjct: 116 PTVMGVSFAYVLPVLSIIRDYNNGQFDSEKQRFRHTMRTVQGSLIISSFVNIIIGYGQAW 175 Query: 123 GKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVAL--------- 173 G + R+F+P++ + ++ L F A+ +P ++ + Sbjct: 176 GNLIRIFSPIIVVPVVSVVSLGL----FLRGFPLLANCVEIGLPMLILLIITQQYLKHAF 231 Query: 174 --VTFITTVYVALKAKGPIRAMPVI---AGALVGYLVSVPLGLANFQ--LVKELPLVSLP 226 ++ I Y L I A I +GA + + L+ P + +P Sbjct: 232 SRISMILERYALLVCLAIIWAFAAILTVSGAYNNVSTATKQSCRTDRAFLMSSAPWIRIP 291 Query: 227 RPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEAPITNKHI-NRGIMSEGIA 285 PF WG P F + + + A +V+ ES G + A S +A A H+ +R I +GI Sbjct: 292 YPFQWGTPIFKASHVFGMFGAAIVASAESTGVFFAASRLAGATAPPAHVVSRSIGLQGIG 351 Query: 286 CSIAGILGAC-GTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAP 344 + GI G+ G T+ EN+GL+ LT++ SR VVQ+ ++ S+F KF AS+P P Sbjct: 352 VLLEGIFGSITGNTASVENVGLLGLTRIGSRRVVQVSTFFMIFFSIFGKFGAFFASIPLP 411 Query: 345 VLGGLTIALYGMISVTGLRLIKDKVELNDRNTLILATSLIVGLGAPQLPPKFLAH----- 399 + G+ L G++ G+ I+ + RN ++ SL + L Q FLA+ Sbjct: 412 IFAGVYCILLGIVVAVGISFIQFTDTNSMRNMYVIGVSLFLSLSIAQY---FLANTSRAG 468 Query: 400 ----------FPRIVASILESGMAIGAITAIVLDQLL 426 F I+ +I S + I A +LD L Sbjct: 469 YGPVRTAGGWFNDILNTIFASAPLVATILATILDNTL 505 >pir||T02307 permease homolog F13P17.3 - Arabidopsis thaliana >gi|3337350|gb|AAC27395.1| (AC004481) putative membrane transporter [Arabidopsis thaliana] Length = 524 Score = 153 bits (383), Expect = 3e-36 Identities = 115/412 (27%), Positives = 187/412 (44%), Gaps = 46/412 (11%) Query: 17 KAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTTIGSRY 76 +AI LG +H + G V +P ++ +G + ++Q +L G+ TLLQT G+R Sbjct: 32 EAIALGFEHYILALGTAVMIPSILVPMMGGDDGDKVRVVQTLLFLQGVNTLLQTLFGTRL 91 Query: 77 PIVQGSSFAFIPGLISI--GKSLG------------MAATEGALIVGGIIEALIGGTGIV 122 P V G S+AF+ +ISI SL M A +GA+IV ++ ++G + + Sbjct: 92 PTVIGGSYAFMVPIISIIHDSSLTRIEDPQLRFLSTMRAVQGAIIVASSVQIILGFSQMW 151 Query: 123 GKVKRLFTPLVTGVTIMLIGFSLAD---------------------VAVKYFFNFYADPS 161 R F+P+ I L GF L + + +Y NF Sbjct: 152 AICSRFFSPIGMVPVIALTGFGLFNRGFPVVGNCVEIGLPMLILFVIFSQYLKNFQFRQF 211 Query: 162 GSSIPRATIVALVTFITTVYVALKAKGPIRAMPVIAGALVGYLVSVPLGLANFQLVKELP 221 A I+AL+ +V L A G + P + + L+ P Sbjct: 212 PVVERFALIIALIIVWAYAHV-LTASGAYKHRP--------HQTQLNCRTDMSNLISSAP 262 Query: 222 LVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEAPITNKHI-NRGIM 280 + +P P WG P F+ ++ A +VS+IES G + A + +A A H+ +RGI Sbjct: 263 WIKIPYPLQWGAPSFDAGHAFAMMAAVLVSLIESTGAFKAAARLASATPPPPHVLSRGIG 322 Query: 281 SEGIACSIAGILGACGTTSYS-ENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILA 339 +GI + G+ G +S S ENIGL+ T+V SR V+QI ++ S+ KF + A Sbjct: 323 WQGIGILLNGLFGTLSGSSVSVENIGLLGSTRVGSRRVIQISAGFMIFFSMLGKFGALFA 382 Query: 340 SMPAPVLGGLTIALYGMISVTGLRLIKDKVELNDRNTLILATSLIVGLGAPQ 391 S+P + + L+G+++ GL ++ + RN I+ SL +GL P+ Sbjct: 383 SIPFTIFAAVYCVLFGLVASVGLSFLQFTNMNSLRNLFIVGVSLFLGLSIPE 434 >pir||B81096 uracil permease NMB1315 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7226557|gb|AAF41690.1| (AE002480) uracil permease [Neisseria meningitidis MC58] Length = 403 Score = 152 bits (380), Expect = 7e-36 Identities = 119/418 (28%), Positives = 201/418 (47%), Gaps = 33/418 (7%) Query: 17 KAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLL-QTTIGSR 75 K + G Q + FGA V VPL+ G L+ LL G+ TLL Q T + Sbjct: 5 KLAVSGAQILFVAFGAMVLVPLLTGLNPALA-----------LLGAGLGTLLFQITTKRK 53 Query: 76 YPIVQGSSFAFIPGLISIGKSLGMAATEGALIVGG----IIEALIGGTGIVGKVKRLFTP 131 PI GSSFAFI +I G+ +T L G + ALI G+ V +L P Sbjct: 54 VPIFLGSSFAFIAPIIYSVGEWGLPSTMFGLFAAGFMYFVFAALIRWRGLAA-VHKLLPP 112 Query: 132 LVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITTVYVALKAKGPIR 191 +V G IM+IG S+A A + I++ TF T V++ ++ Sbjct: 113 VVIGPVIMVIGLSVAVAASSMAMGQADGKQVIDYTDSLILSGFTFAVTAIVSVFGSRMMK 172 Query: 192 AMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVS 251 +P++ G GY++++ +GL + + P ++P + P+ N A + +L + Sbjct: 173 LIPILIGVASGYVLALLMGLVDTASIAHAPWFAVPH---FETPQINWQAALFMLPVAVAP 229 Query: 252 IIESVGDYHAISAIAEAPIT-NKHINRGIMSEGIACSIAGILGACGTTSYSENIGLVALT 310 IE +G AI + T + +++ + +G+ +AG++G T+Y E G V +T Sbjct: 230 AIEHIGGIMAIGNVTGKDYTKDPGLDKTLAGDGLGVCVAGLIGGPPVTTYGEVTGAVMIT 289 Query: 311 KVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLR-LIKDKV 369 K ++ ++ + V ++ F KF LAS+P PV+GG+ + L+G I+ G++ LI KV Sbjct: 290 KNSNPVIMTWAAVFAVCMAFFGKFNAFLASIPMPVMGGIMLLLFGTIASLGVKTLIDAKV 349 Query: 370 ELN-DRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAITAIVLDQLL 426 +L +N +I+++ L G+G L + S +G+ + A+ AI+L+ LL Sbjct: 350 DLMLPKNLVIVSSVLTTGIGGMTLK----------LGSFSFAGVGLCAVLAIMLNSLL 397 >gb|AAF54519.1| (AE003686) CG6293 gene product [Drosophila melanogaster] Length = 573 Score = 148 bits (371), Expect = 9e-35 Identities = 114/431 (26%), Positives = 198/431 (45%), Gaps = 51/431 (11%) Query: 3 PGVLVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEIS--IMIQAVLL 60 P +L +++ +I L QH L M GA V++P ++ A+ +S E+ + I+I ++ Sbjct: 33 PQLLYAINDNPPWYLSIFLAFQHYLTMIGAIVSIPFILTPALCMSDEDANRGIIISTMIF 92 Query: 61 AMGIATLLQTTIGSRYPIVQGSSFAFIPGLISIGK------------------------S 96 GI T Q T G R PIVQG + +F+ ++I Sbjct: 93 VTGIVTYFQATWGVRLPIVQGGTISFLVPTLAILALPQWKCPEQAVMDAMDEAEREELWQ 152 Query: 97 LGMAATEGALIVGGIIEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNF 156 + M GA+ V +++ ++G TG+VGK+ + TPL T+ L+G +L + A + Sbjct: 153 VRMRELSGAIAVSAMVQVILGYTGLVGKILKYVTPLTIVPTVSLVGLTLFEHAAETASKH 212 Query: 157 YADPSGSSIPRATIVALVTFITTVYVALKAKG--------------PIRAMPVIAGALVG 202 + G++ T+ + + V + KG P+ +I L G Sbjct: 213 WGIAVGTT-GMLTLFSQIMSNVPVPILAYRKGHGLEIRQFQLFRLFPVLLTIMIMWGLCG 271 Query: 203 YLVSVPLGLANFQLVKELPLVSL--------PRPFPWGIPEFNLTAIVTLLFAFMVSIIE 254 L + + + ++ L L P P +G P L+ ++ +L + +E Sbjct: 272 ILTATDVFPPSHPSRTDVRLNVLTSAKWFYVPYPGQFGWPSVTLSGVLGMLAGVLACTVE 331 Query: 255 SVGDYHAISAIAEAPITNKH-INRGIMSEGIACSIAGILGAC-GTTSYSENIGLVALTKV 312 S+ Y +S ++ A H INRGI +EG +AG+ GA GT ++ EN+G + +TK+ Sbjct: 332 SLSYYPTVSQMSGAHSPPLHAINRGIGTEGFGTVLAGLWGAGNGTNTFGENVGAIGVTKI 391 Query: 313 ASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVELN 372 SR V+Q +I+V+ + KF I +P V+GG+ ++GMI GL ++ + Sbjct: 392 GSRRVIQWAALIMVLQGVIGKFGAIFILIPDSVVGGIFCVMFGMIIAFGLSTLQYVDLRS 451 Query: 373 DRNTLILATSL 383 RN IL S+ Sbjct: 452 ARNLYILGLSI 462 >pir||T05632 hypothetical protein F20D10.170 - Arabidopsis thaliana >gi|4467111|emb|CAB37545.1| (AL035538) putative protein [Arabidopsis thaliana] >gi|7270788|emb|CAB80470.1| (AL161592) putative protein [Arabidopsis thaliana] Length = 703 Score = 148 bits (369), Expect = 1e-34 Identities = 123/424 (29%), Positives = 200/424 (47%), Gaps = 66/424 (15%) Query: 19 ILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTTIGSRYPI 78 I GLQH L++ G+ V +PLV+ A+ S ++ + +I +LL G+ T+L G+R P+ Sbjct: 189 IYYGLQHYLSLVGSLVFIPLVIVPAMDGSDKDTASVISTMLLLTGVTTILHCYFGTRLPL 248 Query: 79 VQGSSFAFI-PGLISIGKSLGMAATE-----------GALIVGGIIEALIGGTGIVGKVK 126 VQGSSF ++ P L+ I TE GA+IVG + + ++G +G++ + Sbjct: 249 VQGSSFVYLAPVLVVINSEEFRNLTEHKFRDTMRELQGAIIVGSLFQCILGFSGLMSLLL 308 Query: 127 RLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITTVY---VA 183 R P+V T+ +G + FF++ +G+ + + + L+ I T+Y V+ Sbjct: 309 RFINPVVVAPTVAAVGLA--------FFSYGFPQAGTCVEISVPLILLLLIFTLYLRGVS 360 Query: 184 LKAKGPIR--AMPVIAGALVGYLVSVPLGLA------------NFQLVKELPL------- 222 L R A+P+ A + Y + +G A + L+ E Sbjct: 361 LFGHRLFRIYAVPLSALLIWTYAFFLTVGGAYDYRGCNADIPSSNILIDECKKHVYTMKH 420 Query: 223 --------------VSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEA 268 V +P PF WG + LFA V +++ VG YH+ S I A Sbjct: 421 CRTDASNAWRTASWVRIPYPFQWGG-----LGMYLFLFAIPVFLLK-VGTYHSASMIVNA 474 Query: 269 PITNKHI-NRGIMSEGIACSIAGILGA-CGTTSYSENIGLVALTKVASRYVVQIGGIILV 326 + I +RGI EG +AGI G+ G+T+ +ENI + +TKVASR + IG + L+ Sbjct: 475 KRPTRGIVSRGIALEGFCSLLAGIWGSGTGSTTLTENIHTINITKVASRRALVIGAMFLI 534 Query: 327 VLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVELNDRNTLILATSLIVG 386 VLS K ILAS+P + + ++ + GL ++ + RN I+ SL +G Sbjct: 535 VLSFLGKLGAILASIPQALAASVLCFIWALTVSLGLSNLRYTQTASFRNITIVGVSLFLG 594 Query: 387 LGAP 390 L P Sbjct: 595 LSIP 598 >gb|AAB60909.1| (AC001229) Similar to Zea mays permease 1 (gb|U43034). [Arabidopsis thaliana] Length = 535 Score = 141 bits (352), Expect = 1e-32 Identities = 109/406 (26%), Positives = 180/406 (43%), Gaps = 59/406 (14%) Query: 3 PGVLVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVG-----LSKEEISI---- 53 PG+ V+ +A++LG QH L G TV +P ++ T L++E I I Sbjct: 28 PGIQYCVNSPPPWLEAVVLGFQHYLLSLGITVLIPSMLETFFFFFFFFLNRESILIFYAE 87 Query: 54 ---MIQAVLLAMGIATLLQTTIGSRYPIVQGSSFAFIPGLISIGKSL------------- 97 +IQ +L G+ TL Q+ G+R P++ +S+A+I + SI S Sbjct: 88 KVKVIQTLLFVSGLTTLFQSFFGTRLPVIAVASYAYIIPITSIIYSTRFTYYTDPFERFV 147 Query: 98 -GMAATEGALIVGGIIEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNF 156 M + +GALI+ G + LI G+ + R +PL G L + +N Sbjct: 148 RTMRSIQGALIITGCFQVLICILGVWRNIVRFLSPLSIAPLATFTGLGLYHIGFPLIYNM 207 Query: 157 YADPSGSSIPRATIVALVTFITTVYVA------LKAKGPIRAMPVIAGALVGYLVSVPL- 209 + R V L I ++V LK K + + G ++ +PL Sbjct: 208 MQTSFIFQLARCVEVGLPGLILLIFVTQYLPRFLKMKKGVMILDGSRCDRYGMILCIPLV 267 Query: 210 ----------GLANFQ--------------LVKELPLVSLPRPFPWGIPEFNLTAIVTLL 245 G+ + + L+ P + +P PF WG P F++T ++ Sbjct: 268 WLFAQLLTSSGVYDHKSHTTQTSCRTDRTGLITNTPWIYIPYPFQWGSPTFDITDSFAMM 327 Query: 246 FAFMVSIIESVGDYHAISAIAEA-PITNKHINRGIMSEGIACSIAGILGA-CGTTSYSEN 303 A V++ ES G ++A + A PI ++RG G+ + G+LG G T+ +EN Sbjct: 328 AASFVTLFESTGLFYASARYGSATPIPPSVVSRGTCWLGVGVLLNGMLGGITGITTSTEN 387 Query: 304 IGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGL 349 +GL+A+TK+ SR V+QI ++ S+F KF AS+P P++ L Sbjct: 388 VGLLAMTKIGSRRVIQISAAFMIFFSIFGKFGAFFASIPLPIMASL 433 >sp|Q07307|UAPA_EMENI URIC ACID-XANTHINE PERMEASE (UAPA TRANSPORTER) >gi|3286685|emb|CAA50681.1| (X71807) uric acid-xanthine permease [Emericella nidulans] Length = 615 Score = 140 bits (350), Expect = 2e-32 Identities = 118/480 (24%), Positives = 212/480 (43%), Gaps = 69/480 (14%) Query: 9 VDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLL 68 ++EK+ A +LGLQH LAM VT PL++ +++ L + ++ L+ G+ +++ Sbjct: 111 LNEKIPVLLAFILGLQHALAMLAGVVTPPLIISSSLSLPSDLQQYLVSTSLIVCGLLSMV 170 Query: 69 QTT----------IGSRYPIVQGSSFAFIP---------------GLISIGKSLGMAATE 103 Q T IGS V G SF+ I L G L Sbjct: 171 QITRFHIYKTPYYIGSGVLSVMGVSFSIISVASGPFNQMYSNGFCQLDEAGNRLPCPEAY 230 Query: 104 GALI----VGGIIEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYA- 158 G LI ++E L+ ++++F P+VTG T+MLIG SL K + A Sbjct: 231 GRLIGTSACCALVEILLAFVP-PKVIQKIFPPIVTGPTVMLIGISLIGTGFKDWAGGSAC 289 Query: 159 DPSGSSIPRATI-------------VALVTFITTVYVALKAKGPIRAMPVIAGALVGYLV 205 G P AT + + F++ + +++ V+ G LVG +V Sbjct: 290 MDDGMLCPSATAPRPLPWGSPEFIGLGFLVFVSIILCERFGAPIMKSCSVVIGLLVGCIV 349 Query: 206 SVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLTA----IVTLLFAFMVSIIESVGDYHA 261 + G + + P S F W + F L+ ++ ++ F++ E +GD A Sbjct: 350 AAACGYFSHADIDAAPAAS----FIW-VKTFPLSVYGPMVLPIIAVFIICACECIGDVTA 404 Query: 262 ISAIAEAPIT----NKHINRGIMSEGIACSIAGILGACGTTSYSENIGLVALTKVASRYV 317 ++ + I ++++GI +A + T++++N G++ALT+ A+R+ Sbjct: 405 TCDVSRLEVRGGTFESRIQGAVLADGINSVVAALATMTPMTTFAQNNGVIALTRCANRWA 464 Query: 318 VQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVELNDRNTL 377 +IL+V +F KFA + ++P V+GG+ L+ + ++G ++ K RN Sbjct: 465 GYCCCLILIVAGIFAKFAAAIVAIPNSVMGGMKTFLFASVVISGQAIVA-KAPFTRRNRF 523 Query: 378 ILATSLIVGLGA-----------PQLPPKFLAHFPRIVASILESGMAIGAITAIVLDQLL 426 IL S+ +G GA PQ + L F + +LE+G A+ A A++L+ ++ Sbjct: 524 ILTASMALGYGATLVPTWFGNVFPQTENRDLEGFENAIELVLETGFAVTAFVAMLLNAIM 583 >pir||T02719 permease 1 - maize Length = 487 Score = 140 bits (350), Expect = 2e-32 Identities = 120/409 (29%), Positives = 182/409 (44%), Gaps = 45/409 (11%) Query: 19 ILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTTIGSRYPI 78 +L+G QH L M G TV + ++ +G E +I+IQ +L GI TLLQ G+R P Sbjct: 35 VLVGFQHYLVMLGTTVLIATIIVPLMGGGHAEKAIVIQTILFLSGINTLLQVHFGTRLPA 94 Query: 79 VQGSSFAFIPGLISIGKS--------------LGMAATEGALIVGGIIEALIGGTGIVGK 124 V S+ +I ++I S M + +GALI+ G+ +A++G GI Sbjct: 95 VMSGSYTYIYPAVAIILSPRYALLIDPLERFVFTMRSLQGALIIAGVFQAVVGFFGIWRV 154 Query: 125 VKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITTVYVA- 183 R +PL + L G L +FF F + +V LV F Y + Sbjct: 155 FIRFLSPLAAVPFVTLTGLGL------FFFAFPGVTKCIEVGLPALVLLVIFAE--YASH 206 Query: 184 LKAKGP-IRAMPVIAGALVGYL--VSVPLGLANFQLVKELPLVSLPR------------- 227 L AKG + + +AG +L P G Q V LPR Sbjct: 207 LFAKGSFVFSRCAVAGDRRDHLDLPRDPDGGRRLQREGPCDAVQLPRRPLRDHPGLTLGE 266 Query: 228 ---PFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEAPITNKHINRGIMSEGI 284 P GIP F L ++ +L ++ ++ + + +RGI EGI Sbjct: 267 VSLSVPVGIPHFLLPGLLAMLAGSFRRLLSLPHLNRSVKILRRDVLPTLVFSRGIGWEGI 326 Query: 285 ACSIAGILGAC-GTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPA 343 + + G+ G GT + EN GL+A+T+V SR V++I + ++ SLF KF +LAS+P Sbjct: 327 SIILDGMCGTLTGTAASVENAGLLAVTRVGSRRVIKISALFMIFFSLFAKFGAVLASIPL 386 Query: 344 PVLGGLTIALYGMISVTGLRLIKDKVELND-RNTLILATSLIVGLGAPQ 391 P+ L L+ + G L++ LN R IL+ SL +GL PQ Sbjct: 387 PIFAALYCVLFAYSAGAGFSLLQ-YCNLNSLRTKFILSISLFLGLSIPQ 434 >dbj|BAA13244.1| (D87075) similar to Mouse yolk sac permease-like molecule 1 (U25739) [Homo sapiens] Length = 330 Score = 139 bits (348), Expect = 4e-32 Identities = 81/218 (37%), Positives = 126/218 (57%), Gaps = 17/218 (7%) Query: 221 PLVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEAPITNKH-INRGI 279 P +P PF WG+P + ++ +L A + SIIES+GDY+A + ++ AP H INRGI Sbjct: 40 PWFKVPYPFQWGLPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGI 99 Query: 280 MSEGIACSIAGILGAC-GTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGIL 338 EG++C + GI G G+TS S NIG++ +TKV SR V+Q G +++ L + KF+ + Sbjct: 100 FVEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKVGSRRVIQCGAALMLALGMIGKFSALF 159 Query: 339 ASMPAPVLGGLTIALYGMISVTGLRLIKDKVELN-DRNTLILATSLIVGLGAPQLPPKFL 397 AS+P PVLG L L+GMI+ GL ++ ++LN RN +L S+ GL + P +L Sbjct: 160 ASLPDPVLGALFCTLFGMITAVGLSNLQ-FIDLNSSRNLFVLGFSIFFGL----VLPSYL 214 Query: 398 AHFP---------RIVASILESGMAIGAITAIVLDQLL 426 P +++ +L + M +G A +LD + Sbjct: 215 RQNPLVTGITGIDQVLNVLLTTAMFVGGCVAFILDNTI 252 >emb|CAB76872.1| (AL159139) putative uracyl permease [Streptomyces coelicolor A3(2)] Length = 478 Score = 139 bits (347), Expect = 6e-32 Identities = 125/455 (27%), Positives = 206/455 (44%), Gaps = 69/455 (15%) Query: 3 PGVLVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAM 62 PG +V+ DE++ + LG QHV+AMFGA+ P+++G L+ ++ Sbjct: 18 PGAVVRPDERLSWPRTAGLGAQHVVAMFGASFVAPVLMGLDPNLA-----------IMMS 66 Query: 63 GIATL--LQTTIGSRYPIVQGSSFAFIPGLISIGKSLGMAAT-EGALIVGGIIEALIG-- 117 G+AT+ L T G R P G S +F+ I G +AT GA++V G+ L+G Sbjct: 67 GVATVIFLLATRG-RVPSYLGCSLSFVGVAAVIRAQGGTSATVTGAVLVVGVALFLVGLA 125 Query: 118 ----GTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVAL 173 G I+ P+VTG +MLIGF+LA V ++ P+ AL Sbjct: 126 VQRFGARIIHAA---MPPVVTGAVVMLIGFNLAPVTASTYW-----------PQDQWTAL 171 Query: 174 VTFITTVYVALKAKGPIRAMPVIAGALVGYLVSVPLGLA-------------------NF 214 + T + +G + + G + GY++S L +F Sbjct: 172 FVMLFTGLAVVCLRGFWSRIAIFLGLVFGYVLSWALDRIFGKIHSVDGSGKPTDHWRLDF 231 Query: 215 QLVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEAPITNKH 274 V + + LP + P F +AI+ L + I E+ G A+ + + +K Sbjct: 232 SAVGQADWIGLPS---FHGPSFEWSAILVALPVVIALIAENAGHVKAVGEMTGDNLDDK- 287 Query: 275 INRGIMSEGIACSIAGILGACGTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKF 334 + I ++GI ++ +G T+YSENIG++A T+V S ++ L PKF Sbjct: 288 LGTAISADGIGSVLSTAVGGPPNTTYSENIGVMAATRVYSTAAYWAAAGFALLFGLCPKF 347 Query: 335 AGILASMPAPVLGGLTIALYGMISVTGLRL-IKDKVEL-NDRNTLILATSLIVGLGAPQL 392 ++A++P VLGG+T+ LYGMI + G ++ I KV++ N N + A +I+G+G + Sbjct: 348 GAVVAAIPGGVLGGITVILYGMIGLLGAQIWINAKVDMRNPLNLVPAAAGIIIGVGNVSM 407 Query: 393 PPKFLAHFPRIVASILESGMAIGAITAIVLDQLLR 427 + SG+A+G + I LR Sbjct: 408 ---------EFTDTFSLSGIALGTLVVITGYHALR 433 >pir||T24675 hypothetical protein T07G12.2 - Caenorhabditis elegans >gi|3879630|emb|CAB05274.1| (Z82282) Similarity to Bacillus xanthine permease (SW:P42086), contains similarity to Pfam domain: PF00860 (Xanthine/uracil permeases family), Score=600.2, E-value=4.1e-177, N=1 [Caenorhabditis elegans] Length = 540 Score = 138 bits (345), Expect = 1e-31 Identities = 117/470 (24%), Positives = 208/470 (43%), Gaps = 78/470 (16%) Query: 15 PRKAILL--GLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQ---AVLLAMGIATLLQ 69 P K+ + GLQ +L A + P V + E + +Q A ++ GIAT+LQ Sbjct: 16 PHKSAIFFFGLQQMLVCISALLVTPYFVSNLLCAGAETTEVRVQLIAATFISSGIATILQ 75 Query: 70 TTIGSRYPIVQGSSFAFIPGLISIGKSLG-------------MAATEGALIVGGIIEALI 116 TT+ I+ G SFAF P L + G + G+L V +I + Sbjct: 76 TTLA----ILHGPSFAFFPALHTFGDVYPCNSDTDTTQWKEKLQMISGSLFVAVLIMPFL 131 Query: 117 GGTGIVGKVKRLFTPLVTGVTIMLIGF-SLADVAVKYFFNFYADPSGSSIPRATIVALVT 175 G TG+VG++ + P+ +ML+ ++ D+ K ++ + IV ++ Sbjct: 132 GITGMVGRIAKHIGPITIVPMLMLLCIGTVQDIEQKVSHHWIS-----------IVEILL 180 Query: 176 FITTVYVALKAKGPIRAM------------------PVIAGALVGYLVSVPLGLANFQ-- 215 I V + + + P+ A P + G ++ + V L + + + Sbjct: 181 LIIFVVLLEEFEVPMPAFSMEKKAFYTAKMKIFSQFPYLLGIMIAWFVCWILTITDLEPY 240 Query: 216 -------------LVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAI 262 +++ P + + P +G+P+ + I+ + + + IES+G+Y Sbjct: 241 GCSARTDRNESLFVLENTPWIQIQYPLQYGLPKLSAPLIIAFSASMLAATIESIGNYGIC 300 Query: 263 SAIAE-APITNKHINRGIMSEGIACSIAGILGA-CGTTSYSENIGLVALTKVASRYVVQI 320 + I + + +NR + EG +A ++G G T+YSENI ++ +TKV SR +Q Sbjct: 301 ARICQQGSPPSSSMNRAFVVEGFGSMLAALMGVGTGVTTYSENIAIMQVTKVTSRITMQC 360 Query: 321 GGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLRLIK-DKVELN-DRNTLI 378 G+IL+++ +F KFA LA +P ++GG+ A GM + G+ V+L RN I Sbjct: 361 AGVILILMGIFSKFAAFLAMIPEAIIGGVLTA--GMSMICGVAFSNLQSVDLRLSRNLTI 418 Query: 379 LATSLIVGLGAPQLPPKFLAH-----FPRIVASILESGMAIGAITAIVLD 423 + S+I+G P K H I ++L+ M +G + A LD Sbjct: 419 IGLSIILGCTIPAHFEKSPLHSGNKTIDDIFGTLLKMRMLVGGLIAFCLD 468 >sp|P48777|UAPC_EMENI PURINE PERMEASE >gi|1362518|pir||A56382 purine permease, broad specificity - Emericella nidulans >gi|790973|emb|CAA56190.1| (X79796) purine permease [Emericella nidulans] Length = 580 Score = 138 bits (343), Expect = 2e-31 Identities = 128/486 (26%), Positives = 217/486 (44%), Gaps = 74/486 (15%) Query: 9 VDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLS--KEEISIMIQAVLLAMGIAT 66 +++K+ A+LLGLQH LAM +T P+++ + G + +E ++ L+ G+ + Sbjct: 63 LEDKIPLVLALLLGLQHALAMLAGVITPPILLAGSSGANFGADESQYLVSTSLIVSGLLS 122 Query: 67 LLQTT----------IGSRYPIVQGSSFAFIP---GLISIGKSLGMAATEG--------- 104 +Q +G+ V G+SF I G + S G +G Sbjct: 123 AVQMFRLHVYKTRYYVGTGLVSVVGTSFGTITVATGTFNQMYSTGYCPVDGSGNRLPCPK 182 Query: 105 ---ALIVGGIIEALIG-GTGIVGK--VKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYA 158 AL+ + +L+ G + +K LF P+VTG T+ LIG SL A+K + Sbjct: 183 GYGALLATSCLCSLLEIGLSFMSSRLLKALFPPIVTGPTVFLIGASLIGNAMKDWAGGSG 242 Query: 159 DPS-----GSSIPRATI-------------VALVTFITTVYVALKAKGPIRAMPVIAGAL 200 S G+ P A + + F T + +++ VI G L Sbjct: 243 TCSSNPGNGALCPSADAPHPLPWGSAEFIGLGFLVFATIILCERFGSPIMKSCAVIVGLL 302 Query: 201 VGYLVSVPLGLANFQLVKELPLVSLPRPFPWGIPEFNLTA----IVTLLFAFMVSIIESV 256 VG +V+ G + + P+ S F W + F LT I+ LL +MV ++ES+ Sbjct: 303 VGCIVAAACGYFDRSGIDAAPVAS----FIW-VKTFPLTIYAPLILPLLAVYMVIMMESI 357 Query: 257 GDYHAISAIA----EAPITNKHINRGIMSEGIACSIAGILGACGTTSYSENIGLVALTKV 312 GD A ++ E + I G++ GI C +AG+ + +++N G++ALT Sbjct: 358 GDITATCDVSRLQVEGATFDSRIQGGVLGNGITCLLAGLCTITPMSVFAQNNGVIALTPC 417 Query: 313 ASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVELN 372 A+R LVV+ +F KFA L ++P+ VLGG+T L+ ++++G+R I V+ Sbjct: 418 ANRKAGYCCCFFLVVMGIFAKFAAALVAIPSSVLGGMTTFLFSSVAISGVR-IMCSVDWT 476 Query: 373 DRNTLILATSLIVGLGAPQLPPKFLAHFP------------RIVASILESGMAIGAITAI 420 RN IL S VG+ A +P F F + V ++ +G A+ + Sbjct: 477 RRNRFILTASFAVGMAATLVPDWFSYFFTYSGDNHALEGLLQAVELVMANGFAVTGFLGL 536 Query: 421 VLDQLL 426 +L+ +L Sbjct: 537 LLNLIL 542 >gb|AAD39576.1|AC007067_16 (AC007067) T10O24.16 [Arabidopsis thaliana] Length = 600 Score = 136 bits (340), Expect = 4e-31 Identities = 110/409 (26%), Positives = 178/409 (42%), Gaps = 77/409 (18%) Query: 17 KAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTTIGSRY 76 + ILLG QH L M G TV +P ++ + + E+ +IQ +L GI TL Q+ G+R Sbjct: 42 ETILLGFQHYLVMLGTTVLIPTMLVSKIDARNEDKVKLIQTLLFVSGINTLFQSFFGTRL 101 Query: 77 PIVQGSSFAFIPGLISIGKSLG-----------------MAATEGALIVGGIIEALIGGT 119 P V G+S++++P +SI + M +GALI+ + L+G + Sbjct: 102 PAVIGASYSYVPTTMSIVLAARYNDIMDPQKKMQRFEQIMRGIQGALIIASFLHILVGFS 161 Query: 120 GIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITT 179 G+ V R +PL + GF L + F A +P I+ LV F + Sbjct: 162 GLWRNVTRFLSPLSAVPLVAFSGFGLYEQG----FPMLAKCIEIGLPE--IILLVIF--S 213 Query: 180 VYVALKAKGPIRA---------MPVIAGALVGYLVSVPLGLANFQ-------------LV 217 Y+ +G + V+ L Y++++ +N + ++ Sbjct: 214 QYIPHLMQGETCSNFFHRFAVIFSVVIVWLYAYILTIGGAYSNTEINTQISCRTDRAGII 273 Query: 218 KELPLVSLPRPFPW-GIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEA-PITNKHI 275 P + +P P W G P FN I ++ A VS++ES G Y A+S A A PI + Sbjct: 274 SASPWIRVPHPIQWGGAPTFNAGDIFAMMAASFVSLVESTGTYIAVSRYASATPIPPSVL 333 Query: 276 NRGI---------------------------MSEGIACSIAGILGACGTTSYSENIGLVA 308 +RGI + +G + G+ GA TS EN GL+A Sbjct: 334 SRGIGWQVNTQKRLKYFSMASSKLSLLMRFSVFKGFGILLCGLFGAGNATSV-ENAGLLA 392 Query: 309 LTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMI 357 +T+V SR V+Q+ ++ S+ KF I AS+PAP++ L + + Sbjct: 393 VTRVGSRRVIQVAAGFMIFFSILGKFGAIFASIPAPIVAALYCLFFSYV 441 >pir||I40857 hypothetical protein 1 - Clostridium perfringens Length = 188 Score = 132 bits (328), Expect = 9e-30 Identities = 60/156 (38%), Positives = 106/156 (67%), Gaps = 2/156 (1%) Query: 272 NKHINRGIMSEGIACSIAGILGACGTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLF 331 +K + G++S+G+ ++ G++G+C TS+S+NIG+++LTKVASR+V + GI+LV+L Sbjct: 16 DKRVAAGVLSDGVGSALGGLVGSCPNTSFSQNIGIISLTKVASRHVAVMAGILLVILGFL 75 Query: 332 PKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVELNDRNTLILATSLIVGLGAPQ 391 PK A I+ +P PVLGG+ I ++G ++ G+R + + ++L +RN LI+A S+ +GLG Sbjct: 76 PKVAAIITGIPNPVLGGVGIMMFGTVAAAGIRTLSN-IKLTERNLLIIAISMGLGLGV-T 133 Query: 392 LPPKFLAHFPRIVASILESGMAIGAITAIVLDQLLR 427 P + + P + I SG++ G I A++L+ +L+ Sbjct: 134 FRPDVIHNLPEAIRMIFSSGISTGTIAALILNAVLK 169 >sp|P39618|YWDJ_BACSU PUTATIVE PURINE PERMEASE YWDJ >gi|2126970|pir||S39715 conserved hypothetical protein ywdJ - Bacillus subtilis >gi|580876|emb|CAA51616.1| (X73124) ipa-60d [Bacillus subtilis] >gi|2636329|emb|CAB15820.1| (Z99123) alternate gene name: ipa-60d~similar to hypothetical proteins [Bacillus subtilis] Length = 460 Score = 127 bits (315), Expect = 3e-28 Identities = 105/429 (24%), Positives = 187/429 (43%), Gaps = 30/429 (6%) Query: 17 KAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTTIGSRY 76 K +L LQ + A + VP+ V + L + + +IQ+ +GIA ++Q G R Sbjct: 2 KLVLGALQWTAFIIAAAIVVPVAVAQSFHLDHSDSARLIQSTFFVLGIAAVIQCLKGHRL 61 Query: 77 PIVQGSS---------FAFIPGLISIGKSLGMAATEGALIVGGIIEALIGGTGIVGKVKR 127 PI + + +A + G + + +GAL+V + L+ ++ ++ + Sbjct: 62 PINESPAGLWWGVYTIYAGLTGTVFATYGDTLRGLQGALLVSAVCFFLLSVFKVIDRLAK 121 Query: 128 LFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSS---IPRATIVALVTFITTVYVAL 184 LFTP+VTGV ++L+ L+ +K G A +V FI T + Sbjct: 122 LFTPVVTGVYLLLLVMQLSQPIIKGILGIGYRQDGVDGLVFGLALVVIAAAFIMTNSNIM 181 Query: 185 KAKGPIRAMPVIAGALVGYLVSVPLGLANFQLVKELP--LVSLPRPFPWGIPEFNLTAIV 242 K ++ G+++ G A E+P L LP FP+G P FN I+ Sbjct: 182 FFK----QYSILLALFGGWVLFAAAGAAK---PIEMPDRLFQLPSLFPFGTPLFNSGLII 234 Query: 243 TLLFAFMVSIIESVGDYH----AISAIAEAPITNKHINRGIMSEGIACSIAGILGACGTT 298 T +F ++ I+ + A+ ++ P H + + ++G+ GA Sbjct: 235 TSIFITILLIVNMLASMKVVDIAMKKFSKQPDGKHHERHAGFAASFSHLLSGLTGAIAPV 294 Query: 299 SYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMIS 358 S G + TK+ S+ +G I+++V+S+ P F AS+P+PV G + + Sbjct: 295 PISGAAGFIETTKMPSKKPFMLGSILVIVISVIPFFMNTFASLPSPV--GFAVNFVVFSA 352 Query: 359 VTGLRLIK-DKVELND--RNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIG 415 + GL + D E + R I+ SL+ G+G +P L + S+L +G+ +G Sbjct: 353 MGGLAFAEFDSYEKEESKRVRSIIGISLLTGVGIMFVPETALKGLHPVFISLLSNGLVLG 412 Query: 416 AITAIVLDQ 424 + AI DQ Sbjct: 413 TLAAIAADQ 421 >gb|AAF60824.1| (AC024838) contains similarity to Pfam families PF00076 (RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain), score=22.0, E=0.014, N=1) and PF00860 (Xanthine/uracil permeases family, score=292.9, E=4e-84, N=1) [Caenorhabditis elegans] Length = 1100 Score = 123 bits (307), Expect = 3e-27 Identities = 127/526 (24%), Positives = 212/526 (40%), Gaps = 123/526 (23%) Query: 17 KAIL-LGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQ---AVLLAMGIATLLQTTI 72 K IL G Q + + P ++ + + +Q A ++ GIAT+ QTT Sbjct: 16 KGILGFGFQQAMLCMSGLLVYPFLISNCACAGAAAVQLRVQLISATFVSCGIATIFQTTF 75 Query: 73 GSRYPIVQGSSFAFIPGLISIGKSLGMAATE-----------------GALIVGGIIEAL 115 G R ++ G + AF+P L + TE G+L++ + L Sbjct: 76 GLRLSVLHGPAMAFLPPLFAYKTQNLCPYTEHDEVPPEFWMERMREIQGSLLLACFVFIL 135 Query: 116 IGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVT 175 +G TGI G + +L P+ ++L+ S+ + + S + +V + Sbjct: 136 VGMTGIAGHLSKLIGPITIVPLMLLLTTSIVPTIEEKLSLHWI----SMVMLLVVVMMAV 191 Query: 176 FITTVYVAL----KAKGPIRAMPVIAGALVGYLVSVPL-----------------GLAN- 213 ++ V K I + V YL+S+ G A Sbjct: 192 YLENTRVPFYYYNTEKKQIVSTKVRLFGQFPYLLSMLFVWFICFIMTITDLEPYNGAART 251 Query: 214 -----FQLVKELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEA 268 +++E P +P PFP+GIP+ + + + + SIIE++G Y ++ ++ Sbjct: 252 DNNVTMMVLRESPWFQVPLPFPFGIPKISAGIFFGYIASVLASIIENIGSYDLLARTSQQ 311 Query: 269 -PITNKHINRGIMSEG--------------------------------IACSIAGILG-A 294 P INR I EG + IA + G + Sbjct: 312 KPPPKDAINRAIAMEGGEFQFIISENFYNKNFLLFRKIMIINFFLHFCVGSLIAAVTGVS 371 Query: 295 CGTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLT---I 351 G T+Y+ENI L+ +TKVASR +Q G IL++L LF KFA ILAS+P ++GGL I Sbjct: 372 SGVTTYAENIALIHITKVASRATMQFAGFILIMLGLFSKFAAILASIPDALVGGLLTMGI 431 Query: 352 ALYGMISVTGLRLIKDK----------------------------VELN-DRNTLILATS 382 ++ G ++++ L++ + K ++LN RN I+ S Sbjct: 432 SMIGGVAMSNLQVSRRKLNSDFEALFLNMENWQLYFVRSVFNLKMIDLNLCRNLSIMGLS 491 Query: 383 LIVGLGAP---QLPPKFLAHF--PRIVASILESGMAIGAITAIVLD 423 L++GL P + P HF I+ +L M +G + A LD Sbjct: 492 LLLGLIVPLHFEKHPVNTGHFEIDHILNMLLNIKMLVGGVVATFLD 537 >pir||A48878 uric acid/xanthine transport protein - Emericella nidulans Length = 595 Score = 118 bits (293), Expect = 1e-25 Identities = 107/462 (23%), Positives = 197/462 (42%), Gaps = 69/462 (14%) Query: 27 LAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTT----------IGSRY 76 L + VT PL++ +++ L + ++ L+ G+ +++Q T IGS Sbjct: 109 LPCWAGVVTPPLIISSSLSLPSDLQQYLVSTSLIVCGLLSMVQITRFHIYKTPYYIGSGV 168 Query: 77 PIVQGSSFAFIP---------------GLISIGKSL----GMAATEGALIVGGIIEALIG 117 V G SF+ I L G L AA G ++E L+ Sbjct: 169 LSVMGVSFSIISVASGPFNQMYSNGFCQLDEAGNRLPCPEAYAALVGTSACCALVEILLA 228 Query: 118 GTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYAD-PSGSSIPRATI------ 170 ++++F P+VTG T+MLIG SL K + A G P AT Sbjct: 229 FVP-PKVIQKIFPPIVTGPTVMLIGISLIGTGFKDWAGGSACMDDGMLCPSATAPRPLPW 287 Query: 171 -------VALVTFITTVYVALKAKGPIRAMPVIAGALVGYLVSVPLGLANFQLVKELPLV 223 + + F++ + +++ V+ G LVG +V+ G + + P Sbjct: 288 GSPEFIGLGFLVFVSIILCERFGAPVMKSCSVVIGLLVGCIVAAACGYFSHADIDAAPAA 347 Query: 224 SLPRPFPWGIPEFNLTA----IVTLLFAFMVSIIESVGDYHAISAIAEAPITN----KHI 275 S F W + F L+ ++ ++ F++ E +GD A ++ + I Sbjct: 348 S----FIW-VKTFPLSVYGPMVLPIIAVFIICACECIGDVTATCDVSRLEVRGGTFESRI 402 Query: 276 NRGIMSEGIACSIAGILGACGTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFA 335 ++++G +A + T++++N G++ALT A+R+ +IL+V +F KFA Sbjct: 403 QGAVLADGTNSVVAALATMTPMTTFAQNNGVIALTPCANRWAGYCCCLILIVAGIFAKFA 462 Query: 336 GILASMPAPVLGGLTIALYGMISVTGLRLIKDKVELNDRNTLILATSLIVGLGA------ 389 + ++P V+GG+ L+ + ++G ++ K RN IL S+ +G GA Sbjct: 463 AAIVAIPNSVMGGMKTFLFASVVISGQAIVA-KAPFTRRNRFILTASMALGYGATLVPTW 521 Query: 390 -----PQLPPKFLAHFPRIVASILESGMAIGAITAIVLDQLL 426 PQ + L F + +LE+G A+ A A++L+ ++ Sbjct: 522 FGNVFPQTENRDLEGFENAIELVLETGFAVTAFVAMLLNAIM 563 >pir||T24677 hypothetical protein T07G12.4 - Caenorhabditis elegans >gi|3879632|emb|CAB05276.1| (Z82282) predicted using Genefinder~Similarity to Bacillus xanthine permease (SW:P42086), contains similarity to Pfam domain: PF00860 (Xanthine/uracil permeases family), Score=460.6, E-value=4.4e-135, N=1 [Caenorhabditis elegans] Length = 485 Score = 108 bits (268), Expect = 1e-22 Identities = 93/390 (23%), Positives = 172/390 (43%), Gaps = 46/390 (11%) Query: 73 GSRYPIVQGSSFAFIPGLISIGKSLGMAAT--EGALIVGGIIEALIGGTGIVGKVKRLFT 130 G + +V S+ P L+S G+ T G+L +I +G TG+VG++ + Sbjct: 28 GFQQMLVCISALLITPYLVSNLLCAGVETTAISGSLFAAVLIMPFLGLTGMVGRMAKHIG 87 Query: 131 PL-VTGVTIMLIGFSLADVAVKYFFNFYADPSGSSIPRATIVALVTFITTVYVALKAKGP 189 P+ + + I+L + D+ K ++ S I ++A V + V + A Sbjct: 88 PITIVPMLILLCIGVIPDIEHKVSLHWI-----SIIEILILIAFVVLLEEYEVPIPAFSM 142 Query: 190 ------------IRAMPVIAGALVGYLVSVPLGLANFQ---------------LVKELPL 222 P + G ++ + L +++ + +++ P Sbjct: 143 EQKKFNTMKIKLFSQFPYLLGIMIAWFACWILTISDLEPYGSSARTDRNDSLFVLENTPW 202 Query: 223 VSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAE-APITNKHINRGIMS 281 + + P +G P + ++ + + ++IES+G Y + I + + +NR + Sbjct: 203 IQIQYPLQFGFPRLSAPLVIAFTASMLAAMIESIGSYGICARICQQGSPPSSSMNRAFVV 262 Query: 282 EGIACSIAGILGA-CGTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILAS 340 EG +A ++G G T+YSENI ++ +TKV SR +Q G+IL+++ +F KFA LA Sbjct: 263 EGFGSMLAALMGVGTGVTTYSENIAIMQVTKVTSRITMQCAGVILILMGIFSKFAAFLAM 322 Query: 341 MPAPVLGGLTIALYGMISVTGLRLIK-DKVELN-DRNTLILATSLIVGLGAPQLPPKFLA 398 +P ++GG+ A GM + G+ V+L RN I+ S+I+G P K Sbjct: 323 IPEAIIGGVLTA--GMSMICGVAFSNLQSVDLRLSRNLTIIGLSIILGCTIPAHFEKSPL 380 Query: 399 H-----FPRIVASILESGMAIGAITAIVLD 423 H I ++L+ M +G + A LD Sbjct: 381 HSGNKTIDDIFGTLLKMRMLVGGLIAFCLD 410 >pir||H64782 probable membrane protein b0513 - Escherichia coli >gi|1773193|gb|AAB40265.1| (U82664) similar to B. subtilis ywdJ [Escherichia coli] >gi|1786723|gb|AAC73615.1| (AE000157) putative transport [Escherichia coli K12] Length = 435 Score = 103 bits (255), Expect = 3e-21 Identities = 101/427 (23%), Positives = 185/427 (42%), Gaps = 23/427 (5%) Query: 16 RKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTTIGSR 75 R+++L G Q +F TV VP + +A L + + + Q LA +A Q G R Sbjct: 10 RESLLSGFQWFFFIFCNTVVVPPTLLSAFQLPQSSLLTLTQYAFLATALACFAQAFCGHR 69 Query: 76 YPIVQGSSFAFIPGLISI-------GKSLGMAATEGA--LIVGGIIEALIGGTGIVGKVK 126 I++G + +++I G + AT A + + G++ LIG +G+ ++ Sbjct: 70 RAIMEGPGGLWWGTILTITLGEASRGTPINDIATSLAVGIALSGVLTMLIGFSGLGHRLA 129 Query: 127 RLFTPLVTGVTIMLIGFSLADVAVKYFFNF---YADPSGSSI--PRATIVALVTFITTVY 181 RLFTP V + ++++G L + K ADP+ P A VA++ + + Sbjct: 130 RLFTPSVMVLFMLMLGAQLTTIFFKGMLGLPFGIADPNFKIQLPPFALSVAVMCLVLAMI 189 Query: 182 VALKAKGPIRAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGI-PEFNLTA 240 + L + ++ G + G+L+ ++ L EL P + P LTA Sbjct: 190 IFLPQR--FARYGLLVGTITGWLLWYFCFPSSHSLSGELHWQWFPLGSGGALSPGIILTA 247 Query: 241 IVTLLFAFMVSIIESVGDYHAISAI-AEAPITNKHINRGIMSEGIACSIAGILGACGTTS 299 ++T L V+I + G + N R ++ G I L + Sbjct: 248 VITGL----VNISNTYGAIRGTDVFYPQQGAGNTRYRRSFVATGFMTLITVPLAVIPFSP 303 Query: 300 YSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISV 359 + +IGL+ T +R G +I ++++L P + S+P PV + + Y + Sbjct: 304 FVSSIGLLTQTGDYTRRSFIYGSVICLLVALVPALTRLFCSIPLPVSSAVMLVSYLPLLF 363 Query: 360 TGLRLIKDKVELNDRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAITA 419 + L + ++ RN LA L VG+ LPP +L P + +L +G+ +G + A Sbjct: 364 SAL-VFSQQITFTARNIYRLALPLFVGIFLMALPPVYLQDLPLTLRPLLSNGLLVGILLA 422 Query: 420 IVLDQLL 426 +++D L+ Sbjct: 423 VLMDNLI 429 >sp|P77328|YBBY_ECOLI PUTATIVE PURINE PERMEASE YBBY >gi|2735239|gb|AAB93854.1| (U89279) GlxB4 [Escherichia coli] Length = 433 Score = 103 bits (255), Expect = 3e-21 Identities = 101/427 (23%), Positives = 185/427 (42%), Gaps = 23/427 (5%) Query: 16 RKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAMGIATLLQTTIGSR 75 R+++L G Q +F TV VP + +A L + + + Q LA +A Q G R Sbjct: 8 RESLLSGFQWFFFIFCNTVVVPPTLLSAFQLPQSSLLTLTQYAFLATALACFAQAFCGHR 67 Query: 76 YPIVQGSSFAFIPGLISI-------GKSLGMAATEGA--LIVGGIIEALIGGTGIVGKVK 126 I++G + +++I G + AT A + + G++ LIG +G+ ++ Sbjct: 68 RAIMEGPGGLWWGTILTITLGEASRGTPINDIATSLAVGIALSGVLTMLIGFSGLGHRLA 127 Query: 127 RLFTPLVTGVTIMLIGFSLADVAVKYFFNF---YADPSGSSI--PRATIVALVTFITTVY 181 RLFTP V + ++++G L + K ADP+ P A VA++ + + Sbjct: 128 RLFTPSVMVLFMLMLGAQLTTIFFKGMLGLPFGIADPNFKIQLPPFALSVAVMCLVLAMI 187 Query: 182 VALKAKGPIRAMPVIAGALVGYLVSVPLGLANFQLVKELPLVSLPRPFPWGI-PEFNLTA 240 + L + ++ G + G+L+ ++ L EL P + P LTA Sbjct: 188 IFLPQR--FARYGLLVGTITGWLLWYFCFPSSHSLSGELHWQWFPLGSGGALSPGIILTA 245 Query: 241 IVTLLFAFMVSIIESVGDYHAISAI-AEAPITNKHINRGIMSEGIACSIAGILGACGTTS 299 ++T L V+I + G + N R ++ G I L + Sbjct: 246 VITGL----VNISNTYGAIRGTDVFYPQQGAGNTRYRRSFVATGFMTLITVPLAVIPFSP 301 Query: 300 YSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISV 359 + +IGL+ T +R G +I ++++L P + S+P PV + + Y + Sbjct: 302 FVSSIGLLTQTGDYTRRSFIYGSVICLLVALVPALTRLFCSIPLPVSSAVMLVSYLPLLF 361 Query: 360 TGLRLIKDKVELNDRNTLILATSLIVGLGAPQLPPKFLAHFPRIVASILESGMAIGAITA 419 + L + ++ RN LA L VG+ LPP +L P + +L +G+ +G + A Sbjct: 362 SAL-VFSQQITFTARNIYRLALPLFVGIFLMALPPVYLQDLPLTLRPLLSNGLLVGILLA 420 Query: 420 IVLDQLL 426 +++D L+ Sbjct: 421 VLMDNLI 427 >gb|AAA92292.1| (U25739) YSPL-1 form 1 [Mus musculus] Length = 611 Score = 96.3 bits (236), Expect = 6e-19 Identities = 102/434 (23%), Positives = 178/434 (40%), Gaps = 60/434 (13%) Query: 20 LLGLQHVLAMFGATVTVPLVV--GTAVGLSKEEISIMIQAVLLAMGIATLLQTTIGSRYP 77 LL LQH L + L++ G G + ++ + + G++T+LQT +GSR P Sbjct: 53 LLALQHFLVLASLLWASHLLLLHGLPPGGLSYPPAQLLASSFFSCGLSTVLQTWMGSRLP 112 Query: 78 IVQGSSFAF-IPGLISIGKSLGMAA-------------------------------TEGA 105 ++Q S F IP L+ + L + GA Sbjct: 113 LIQAPSLEFLIPALVLTNQKLPLTTKTPGNASLSLPLCSLTRSCHGLELWNTSLREVSGA 172 Query: 106 LIVGGIIEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYADPSGSSI 165 ++V G+++ IG G+ G+V PLV ++++ G S A K F + G ++ Sbjct: 173 VVVSGLLQGTIGLLGVPGRVFPYCGPLVLAPSLVVAGLS----AHKEVAQFCSAHWGLAL 228 Query: 166 PRATIVALVT-FITTVYVALKAKGP-----------IRAMPVIAGALVGYLVSVPLGLAN 213 ++ + + + + + L + P R + V+A + +S +G + Sbjct: 229 LLILLMVVCSQHLGSCQIPLCSWRPSSTSTHICIPVFRLLSVLAPVACVWFISAFVGTSV 288 Query: 214 FQLV----KELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAISAIAEAP 269 L + P LP P W P A+ + + + S+G Y + Sbjct: 289 IPLQLSEPSDAPWFWLPHPGEWEWPLLTPRALAAGISMALAASTSSLGCYALCGQLLRLS 348 Query: 270 ITNKHI-NRGIMSEGIACSIAGILGA-CGTTSYSENIGLVALTKVASRYVVQIGGIILVV 327 H +RG+ EG+ +AG+LG+ GT S N+G V+L + SR V + G+ + Sbjct: 349 PPPPHACSRGLSLEGLGSVLAGLLGSPLGTASSFPNVGTVSLFQTGSRRVAHLVGLFCMG 408 Query: 328 LSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVELNDRNTLILATSLIVGL 387 L L P+ A + S+P PVLGG+ ++ G + RN I+ S+ + L Sbjct: 409 LGLSPRLAQLFTSIPLPVLGGVLGVTQAVVLSAGFSSFHLADIDSGRNVFIVGFSIFMAL 468 Query: 388 GAPQLPPKFLAHFP 401 L P++L P Sbjct: 469 ----LLPRWLREAP 478 >gb|AAA92293.1| (U25739) YSPL-1 form 2 [Mus musculus] Length = 505 Score = 82.7 bits (201), Expect = 7e-15 Identities = 88/380 (23%), Positives = 153/380 (40%), Gaps = 58/380 (15%) Query: 72 IGSRYPIVQGSSFAF-IPGLISIGKSLGMAA----------------------------- 101 +GSR P++Q S F IP L+ + L + Sbjct: 1 MGSRLPLIQAPSLEFLIPALVLTNQKLPLTTKTPGNASLSLPLCSLTRSCHGLELWNTSL 60 Query: 102 --TEGALIVGGIIEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSLADVAVKYFFNFYAD 159 GA++V G+++ IG G+ G+V PLV ++++ G S A K F + Sbjct: 61 REVSGAVVVSGLLQGTIGLLGVPGRVFPYCGPLVLAPSLVVAGLS----AHKEVAQFCSA 116 Query: 160 PSGSSIPRATIVALVT-FITTVYVALKAKGP-----------IRAMPVIAGALVGYLVSV 207 G ++ ++ + + + + + L + P R + V+A + +S Sbjct: 117 HWGLALLLILLMVVCSQHLGSCQIPLCSWRPSSTSTHICIPVFRLLSVLAPVACVWFISA 176 Query: 208 PLGLANFQLV----KELPLVSLPRPFPWGIPEFNLTAIVTLLFAFMVSIIESVGDYHAIS 263 +G + L + P LP P W P A+ + + + S+G Y Sbjct: 177 FVGTSVIPLQLSEPSDAPWFWLPHPGEWEWPLLTPRALAAGISMALAASTSSLGCYALCG 236 Query: 264 AIAEAPITNKHI-NRGIMSEGIACSIAGILGA-CGTTSYSENIGLVALTKVASRYVVQIG 321 + H +RG+ EG+ +AG+LG+ GT S N+G V+L + SR V + Sbjct: 237 QLLRLSPPPPHACSRGLSLEGLGSVLAGLLGSPLGTASSFPNVGTVSLFQTGSRRVAHLV 296 Query: 322 GIILVVLSLFPKFAGILASMPAPVLGGLTIALYGMISVTGLRLIKDKVELNDRNTLILAT 381 G+ + L L P+ A + S+P PVLGG+ ++ G + RN I+ Sbjct: 297 GLFCMGLGLSPRLAQLFTSIPLPVLGGVLGVTQAVVLSAGFSSFHLADIDSGRNVFIVGF 356 Query: 382 SLIVGLGAPQLPPKFLAHFP 401 S+ + L L P++L P Sbjct: 357 SIFMAL----LLPRWLREAP 372 >gb|AAF34271.1| (M14339) unknown [Streptococcus pneumoniae] Length = 153 Score = 82.3 bits (200), Expect = 1e-14 Identities = 45/151 (29%), Positives = 79/151 (51%), Gaps = 5/151 (3%) Query: 278 GIMSEGIACSIAGILGACGTTSYSENIGLVALTKVASRYVVQIGGIILVVLSLFPKFAGI 337 G +EG+A + GI T +S+N+GLV L+ + R + LV+L L PKF + Sbjct: 1 GYRAEGLAVLLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGAL 60 Query: 338 LASMPAPVLGGLTIALYGMISVTGLRLIKDKVEL--NDRNTLILATSLIVGLGAPQLPPK 395 +P+ VLGG + ++G +S+ G++++ +V+ N+ N LI A S+ G+G Sbjct: 61 AQIIPSSVLGGAMLVMFGFVSIQGMQILA-RVDFANNEHNFLIAAVSIAAGVGLNN--SN 117 Query: 396 FLAHFPRIVASILESGMAIGAITAIVLDQLL 426 P +G+ + ++ AIVL+ +L Sbjct: 118 LFVSMPTAFQMFFSNGIVVASLLAIVLNAVL 148 >gb|AAB41234.1| (U83501) permease homolog [Arabidopsis thaliana] Length = 199 Score = 74.1 bits (179), Expect = 3e-12 Identities = 51/157 (32%), Positives = 75/157 (47%), Gaps = 16/157 (10%) Query: 3 PGVLVKVDEKVEPRKAILLGLQHVLAMFGATVTVPLVVGTAVGLSKEEISIMIQAVLLAM 62 PGV V P I+LG QH + M G TV +P ++ +G E + +I VL Sbjct: 18 PGVEFCVSSS--PNWRIVLGFQHYIVMLGTTVIIPSILVPLMGGGDVEKAEVINTVLFVS 75 Query: 63 GIATLLQTTIGSRYPIVQGSSFAFIPGLISIGKSL--------------GMAATEGALIV 108 GI TLLQ+ GSR P+V G+S+A++ + I S M A +GALI+ Sbjct: 76 GINTLLQSLFGSRLPVVMGASYAYLIPALYITFSYRFTYYLHPHLRFEETMRAIQGALII 135 Query: 109 GGIIEALIGGTGIVGKVKRLFTPLVTGVTIMLIGFSL 145 I ++G G+ + R +PL ++L G L Sbjct: 136 ASISHMIMGFFGLWRILVRFLSPLSAAPLVILTGVGL 172 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.325 0.143 0.401 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 142189527 Number of Sequences: 2977 Number of extensions: 5782558 Number of successful extensions: 20412 Number of sequences better than 1.0e-10: 83 Number of HSP's better than 0.0 without gapping: 45 Number of HSP's successfully gapped in prelim test: 38 Number of HSP's that attempted gapping in prelim test: 20004 Number of HSP's gapped (non-prelim): 132 length of query: 427 length of database: 189,106,746 effective HSP length: 56 effective length of query: 371 effective length of database: 155,591,474 effective search space: 57724436854 effective search space used: 57724436854 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 40 (21.5 bits) S2: 166 (69.1 bits)