BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1841 (putP-2) DE:proline permease (putP-2)
         (537 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||A75123 proline permease (putp-2) PAB1841 - Pyrococcus abyss...  1075  0.0
pir||C71008 probable proline permease - Pyrococcus horikoshii >g...  1008  0.0
pir||D75188 proline symporter (proline permease). PAB2354 - Pyro...   360  2e-98
pir||H82382 sodium/proline symporter VCA1071 [imported] - Vibrio...   323  4e-87
pir||T44298 proline transporter [imported] - Bacillus halodurans...   321  2e-86
sp|O06493|OPUE_BACSU OSMOREGULATED PROLINE TRANSPORTER (SODIUM/P...   304  1e-81
pir||B81297 sodium/proline symporter Cj1502c [imported] - Campyl...   303  2e-81
dbj|BAB06425.1| (AP001516) proline transporter [Bacillus halodur...   300  4e-80
pir||G64526 sodium/proline symporter - Helicobacter pylori (stra...   299  6e-80
pir||A71980 sodium/proline symporter - Helicobacter pylori (stra...   298  1e-79
pir||T48676 proline uptake protein [validated] - Staphylococcus ...   292  6e-78
gb|AAA79365.1| (U06451) proline permease homolog [Staphylococcus...   292  8e-78
pir||F83547 sodium/proline symporter PutP PA0783 [imported] - Ps...   291  2e-77
gb|AAA99282.1| (L01140) proline permease [Salmonella sp.] >gi|15...   290  3e-77
gb|AAA24465.1| (L01152) proline permease [Escherichia coli]           289  7e-77
gb|AAA24461.1| (L01132) proline permease [Escherichia coli] >gi|...   288  1e-76
gb|AAA99281.1| (L01139) proline permease [Salmonella sp.]             287  2e-76
gb|AAA99284.1| (L01142) proline permease [Salmonella sp.] >gi|15...   287  2e-76
gb|AAA99286.1| (L01144) proline permease [Salmonella sp.] >gi|15...   287  2e-76
sp|P10502|PUTP_SALTY SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)...   287  2e-76
gb|AAA27199.1| (L01135) proline permease [Salmonella typhimurium]     287  2e-76
gb|AAA26389.1| (L01134) proline permease [Rickettsia typhi]           287  2e-76
gb|AAA24466.1| (L01153) proline permease [Escherichia coli] >gi|...   287  2e-76
sp|P07117|PUTP_ECOLI SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)...   287  3e-76
gb|AAA24463.1| (L01150) proline permease [Escherichia coli] >gi|...   287  3e-76
gb|AAA99278.1| (L01136) proline permease [Salmonella sp.]             287  3e-76
gb|AAA24462.1| (L01133) proline permease [Escherichia coli]           287  3e-76
gb|AAA99279.1| (L01137) proline permease [Salmonella sp.]             287  3e-76
gb|AAA99280.1| (L01138) proline permease [Salmonella sp.]             287  3e-76
gb|AAA24468.1| (L01155) proline permease [Escherichia coli]           286  3e-76
pir||JC2382 sodium/proline symporter - Pseudomonas fluorescens >...   286  5e-76
gb|AAA99288.1| (L01146) proline permease [Salmonella sp.] >gi|15...   286  5e-76
gb|AAA99291.1| (L01149) proline permease [Salmonella sp.]             286  6e-76
pir||S10220 sodium/proline symporter - Salmonella typhimurium         284  1e-75
gb|AAA99290.1| (L01148) proline permease [Salmonella sp.]             284  2e-75
pir||G81202 sodium/proline symporter NMB0402 [imported] - Neisse...   280  3e-74
gb|AAF25001.1|AF153207_2 (AF153207) proline permease [Pseudomona...   278  1e-73
pir||B69759 sodium/proline symporter ycgO - Bacillus subtilis >g...   277  2e-73
gb|AAG19342.1| (AE005029) proline permease; PutP [Halobacterium ...   277  3e-73
sp|P45174|PUTP_HAEIN SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)...   275  7e-73
emb|CAA70363.1| (Y09163) proline transport system [Corynebacteri...   266  4e-70
pir||E75138 osmoregulated proline transporter PAB0609 - Pyrococc...   255  1e-66
pir||C69115 sodium/proline symporter (proline permease) - Methan...   191  1e-47
pir||D65118 pantothenate permease [validated] - Escherichia coli...   184  2e-45
sp|P16256|PANF_ECOLI SODIUM/PANTOTHENATE SYMPORTER (PANTOTHENATE...   184  2e-45
sp|P44963|PANF_HAEIN SODIUM/PANTOTHENATE SYMPORTER (PANTOTHENATE...   180  4e-44
gb|AAF45263.1| (AF230602) proline permease [Escherichia coli] >g...   171  2e-41
gb|AAF45280.1| (AF230619) proline permease [Escherichia coli]         171  2e-41
gb|AAF45283.1| (AF230622) proline permease [Escherichia coli]         171  2e-41
gb|AAF45285.1| (AF230624) proline permease [Escherichia coli]         171  2e-41
gb|AAF45264.1| (AF230603) proline permease [Escherichia coli] >g...   170  4e-41
gb|AAF45286.1| (AF230625) proline permease [Escherichia coli]         168  1e-40
gi|11497636 proline permease (putP-1) [Archaeoglobus fulgidus] >...   163  4e-39
pir||JU0296 pantothenate permease - Escherichia coli >gi|147067|...   153  3e-36
pir||E70201 pantothenate permease (panF) homolog - Lyme disease ...   142  1e-32
dbj|BAB07462.1| (AP001519) Na+/solute symporter (Ssf family) [Ba...   141  1e-32
gi|11498674 pantothenate permease (panF-1) [Archaeoglobus fulgid...   139  7e-32
pir||F83241 probable sodium:solute symporter PA3234 [imported] -...   138  1e-31
gi|11498821 proline permease (putP-3) [Archaeoglobus fulgidus] >...   138  2e-31
gi|11498574 proline permease (putP-2) [Archaeoglobus fulgidus] >...   137  4e-31
pir||H71097 hypothetical protein PH1044 - Pyrococcus horikoshii ...   134  2e-30
sp|P32705|YJCG_ECOLI HYPOTHETICAL 59.2 KD PROTEIN IN SOXR-ACS IN...   134  2e-30
pir||E70480 probable sodium/proline symporter ssf [similarity] -...   134  2e-30
gb|AAG20007.1| (AE005081) pantothenate permease; PanF [Halobacte...   128  1e-28
pir||E82043 probable sodium/solute symporter VC2705 [imported] -...   124  2e-27
pir||S52839 dhlC protein - Xanthobacter autotrophicus >gi|763398...   124  3e-27
sp|P39599|YWCA_BACSU HYPOTHETICAL 55.0 KD PROTEIN IN EPR-GALK IN...   122  1e-26
gi|11497853 pantothenate permease (panF-3) [Archaeoglobus fulgid...   118  1e-25
pir||C82582 Na+-dependent symport homolog XF2251 [imported] - Xy...   116  5e-25
emb|CAA94864.1| (Z71176) phenylacetic acid permease [Pseudomonas...   113  4e-24
sp|P96169|SGLT_VIBPA SODIUM/GLUCOSE COTRANSPORTER (NA(+)/GLUCOSE...   109  8e-23
dbj|BAA11215.1| (D78137) Na+/glucose symporter [Vibrio parahaemo...   109  1e-22
pir||S75887 hypothetical protein - Synechocystis sp. (strain PCC...   108  1e-22
pir||E83468 probable sodium:solute symport protein PA1418 [impor...   106  5e-22
pir||B69833 metabolite permease homolog yhjB - Bacillus subtilis...   105  1e-21
pir||H75513 probable sodium/proline symporter DR0477 [similarity...   105  1e-21
gb|AAF54633.1| (AE003691) CG6723 gene product [Drosophila melano...   105  2e-21
emb|CAB59438.1| (AL132644) putative transmembrane transport prot...   104  2e-21
pir||T03475 transmembrane protein - Rhodobacter capsulatus >gi|3...   104  3e-21
dbj|BAB05941.1| (AP001514) Na+/myo-inositol cotransporter [Bacil...   101  2e-20
pir||C69903 proline permease homolog yodF - Bacillus subtilis >g...   100  4e-20
emb|CAC17810.1| (AJ276242) sodium iodide symporter [Sus scrofa]        99  9e-20
emb|CAC17816.1| (AJ276292) sodium iodide symporter [Sus scrofa]        99  9e-20
gb|AAB81169.1| (AF006665) YolC [Bacillus subtilis]                     99  1e-19
pir||T35201 probable transmembrane transport - Streptomyces coel...    99  1e-19
gb|AAG01741.1|AF251267_1 (AF251267) low affinity sodium-glucose ...    95  2e-18
pir||E72071 hypothetical proline permease - Chlamydophila pneumo...    95  2e-18
gb|AAF73651.1| (AE002186) sodium:solute symporter family protein...    95  2e-18
emb|CAB95932.1| (AL359989) putative sodium:solute symporter [Str...    94  5e-18
gi|6981552 solute carrier family 5, member alpha 1 (Na+/glucose ...    93  7e-18
dbj|BAA19172.1| (AB000729) Na/glucose cotransporter [Rattus norv...    93  7e-18
gi|4507035 solute carrier family 5 (sodium iodide symporter), me...    92  1e-17
dbj|BAA24835.1| (D87920) sodium iodide symporter [Homo sapiens]        92  1e-17
emb|CAC00574.1| (AL109659) dJ1024N4.1 (novel Sodium:solute sympo...    92  2e-17
pir||D72694 hypothetical protein APE0972 - Aeropyrum pernix (str...    90  6e-17
emb|CAB94614.1| (AL359214) putative permease [Streptomyces coeli...    90  8e-17
gi|11498804 pantothenate permease (panF-2) [Archaeoglobus fulgid...    89  1e-16
pir||S68513 thyroid iodide transport protein - rat >gi|1399954|g...    87  4e-16
pir||G83610 probable sodium:solute symporter PA0287 [imported] -...    87  4e-16
sp|P23723|PUTP_KLEPN SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)...    85  3e-15
prf||2204393A Na/I symporter [Rattus norvegicus]                       84  4e-15
emb|CAC16517.1| (AL450223) putative integral membrane transport ...    83  6e-15
gb|AAK42614.1| Metabolite permease, putative [Sulfolobus solfata...    82  1e-14
gb|AAA66065.1| (U08813) 597 aa protein related to Na/glucose cot...    82  2e-14
pir||A82432 sodium/solute symporter VCA0667 [imported] - Vibrio ...    81  3e-14
pir||T28017 hypothetical protein ZK822.5 - Caenorhabditis elegan...    80  8e-14
pir||T32478 hypothetical protein F52H2.4 - Caenorhabditis elegan...    78  2e-13
emb|CAB88444.1| (AL353815) putative sodium-coupled permease [Str...    76  1e-12
gb|AAB39701.1| (U72716) unknown [Drosophila melanogaster] >gi|73...    75  2e-12
gb|AAF57191.1| (AE003779) CG2196 gene product [Drosophila melano...    74  5e-12
gb|AAC12270.1| (AF026554) sodium-dependent multi-vitamin transpo...    72  2e-11
gb|AAF52616.1| (AE003620) CG8451 gene product [Drosophila melano...    72  2e-11
gb|AAK42292.1| Metabolite permease, putative [Sulfolobus solfata...    71  3e-11
pir||S74025 conserved hypothetical protein c0207 - Sulfolobus so...    71  3e-11
emb|CAC11445.1| (AL445063) conserved hypothetical membrane prote...    71  3e-11
gb|AAF46260.1| (AE003440) CG9657 gene product [Drosophila melano...    69  9e-11

>pir||A75123 proline permease (putp-2) PAB1841 - Pyrococcus abyssi  (strain
           Orsay) >gi|5458209|emb|CAB49698.1| (AJ248285) proline
           permease (putP-2) [Pyrococcus abyssi]
           Length = 537
           
 Score = 1075 bits (2749), Expect = 0.0
 Identities = 537/537 (100%), Positives = 537/537 (100%)

Query: 1   MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60
           MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML
Sbjct: 1   MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60

Query: 61  GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTK 120
           GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTK
Sbjct: 61  GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTK 120

Query: 121 LIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAV 180
           LIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAV
Sbjct: 121 LIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAV 180

Query: 181 VWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAI 240
           VWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAI
Sbjct: 181 VWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAI 240

Query: 241 GYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVAS 300
           GYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVAS
Sbjct: 241 GYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVAS 300

Query: 301 GSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVL 360
           GSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVL
Sbjct: 301 GSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVL 360

Query: 361 GQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWW 420
           GQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWW
Sbjct: 361 GQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWW 420

Query: 421 KRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTL 480
           KRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTL
Sbjct: 421 KRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTL 480

Query: 481 FIIIIVSLLTKPPEDVVKLHEELFKKVPIEKSEKIKTARMKSQAENVFDFAVSSGLL 537
           FIIIIVSLLTKPPEDVVKLHEELFKKVPIEKSEKIKTARMKSQAENVFDFAVSSGLL
Sbjct: 481 FIIIIVSLLTKPPEDVVKLHEELFKKVPIEKSEKIKTARMKSQAENVFDFAVSSGLL 537


>pir||C71008 probable proline permease - Pyrococcus horikoshii
           >gi|3257784|dbj|BAA30467.1| (AP000006) 537aa long
           hypothetical proline permease [Pyrococcus horikoshii]
           Length = 537
           
 Score = 1008 bits (2577), Expect = 0.0
 Identities = 490/537 (91%), Positives = 519/537 (96%)

Query: 1   MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60
           MN GIL GFLIYLV+LAYIGWWAN+YTKTE+QYF+GGRKVHVLAATLSDKASDFSGWLML
Sbjct: 1   MNLGILLGFLIYLVLLAYIGWWANRYTKTEEQYFIGGRKVHVLAATLSDKASDFSGWLML 60

Query: 61  GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTK 120
           GYPG+AFK GLGAFWA IGCLFGTLADYLLIGPRLRIYAGKFR+ITLPDYLEARLKDNTK
Sbjct: 61  GYPGTAFKTGLGAFWAAIGCLFGTLADYLLIGPRLRIYAGKFRSITLPDYLEARLKDNTK 120

Query: 121 LIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAV 180
           LIRILSAAIIL+FMTAYVAAQFAAGGKTF++AF VSVTTGILITVIILTAYVITGGFFAV
Sbjct: 121 LIRILSAAIILIFMTAYVAAQFAAGGKTFSEAFGVSVTTGILITVIILTAYVITGGFFAV 180

Query: 181 VWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAI 240
           VWTDVVQAMFMLLTLIIMPILAL EIGGLD+ATQII SV+P KLHPFGGATG AAIVFAI
Sbjct: 181 VWTDVVQAMFMLLTLIIMPILALAEIGGLDKATQIIGSVNPAKLHPFGGATGLAAIVFAI 240

Query: 241 GYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVAS 300
           GYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFAL  +
Sbjct: 241 GYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALAIN 300

Query: 301 GSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVL 360
           GSIK++DPE+IVPAMA+HFLP W+AGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVL
Sbjct: 301 GSIKIDDPEKIVPAMAVHFLPSWIAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVL 360

Query: 361 GQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWW 420
           GQELGKKQMVNISR+VVA V+L+AMWFAI+GPKVIYQMVATAWGGLAVGFGPILTLSLWW
Sbjct: 361 GQELGKKQMVNISRVVVAIVSLIAMWFAISGPKVIYQMVATAWGGLAVGFGPILTLSLWW 420

Query: 421 KRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTL 480
           KRVTKEAGI+GM YGLISEV+LEAKIYGWAFNP APGFFGTLG+WFNGVPVFFINFF+TL
Sbjct: 421 KRVTKEAGIIGMGYGLISEVLLEAKIYGWAFNPNAPGFFGTLGKWFNGVPVFFINFFITL 480

Query: 481 FIIIIVSLLTKPPEDVVKLHEELFKKVPIEKSEKIKTARMKSQAENVFDFAVSSGLL 537
            +IIIVSLLTKPPEDVVKLH+ELFKKVPIEKSEKIK AR KSQAENVFDFA++SGLL
Sbjct: 481 LVIIIVSLLTKPPEDVVKLHKELFKKVPIEKSEKIKVARAKSQAENVFDFAIASGLL 537


>pir||D75188 proline symporter (proline permease). PAB2354 - Pyrococcus abyssi
           (strain Orsay) >gi|5457464|emb|CAB48955.1| (AJ248283)
           PROLINE SYMPORTER (PROLINE PERMEASE). [Pyrococcus
           abyssi]
           Length = 492
           
 Score =  360 bits (914), Expect = 2e-98
 Identities = 186/503 (36%), Positives = 299/503 (58%), Gaps = 30/503 (5%)

Query: 6   LFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65
           L  FL  L++   +G++A K TK+E+ +FVGGR +  +   LS  +S  S WL+LG  G 
Sbjct: 14  LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73

Query: 66  AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRIL 125
           A+K G+ A WA +G +   +  ++ +G RLR ++ +F AIT+PDY EAR +D +K++RI 
Sbjct: 74  AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRIA 133

Query: 126 SAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDV 185
           ++ II++F+T+YV AQF AG KT + A  +S+ T ++I+V+++  Y+I GGF AV + DV
Sbjct: 134 ASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYNDV 193

Query: 186 VQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASW 245
           ++A+ M++ L+++P++A+ ++GG +   +++ ++DP  ++P+    G       IG+   
Sbjct: 194 IRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGVVIGFLGIGF--- 250

Query: 246 IVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVASGS-IK 304
             G  GQPHI+ RYMS++DP KLR   + +   W  ++ WGA F G  G A+V   S + 
Sbjct: 251 --GSPGQPHIIVRYMSIDDPNKLRVSTV-VGTFWNVVLAWGAIFVGLAGRAIVPDVSQLP 307

Query: 305 VEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVL--GQ 362
            ++ E I P ++  + P  + G +I GI +A++STADSQLLV +S + +D+Y +V+  G 
Sbjct: 308 GKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGT 367

Query: 363 ELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWKR 422
           ++ +K  + ISR+ V  V  +A   A     +I+  V  AWGGL   FGP L LSL+WK 
Sbjct: 368 KIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKG 427

Query: 423 VTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTLFI 482
            TK   + GM  G I+ ++       W        +   +   +  VP F  +   T   
Sbjct: 428 TTKWGVLAGMIVGTITTIV-------WKL------YLKPITGLYELVPAFIFSLIAT--- 471

Query: 483 IIIVSLLTKPPEDVVKLHEELFK 505
            IIVS++TKPPE+V    EEL K
Sbjct: 472 -IIVSMITKPPENV----EELMK 489


>pir||H82382 sodium/proline symporter VCA1071 [imported] - Vibrio cholerae
           (group O1 strain N16961) >gi|9658517|gb|AAF96965.1|
           (AE004432) sodium/proline symporter [Vibrio cholerae]
           Length = 496
           
 Score =  323 bits (818), Expect = 4e-87
 Identities = 184/514 (35%), Positives = 284/514 (54%), Gaps = 28/514 (5%)

Query: 2   NFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLG 61
           +F I   F++YL+++  IG +A + TK    YF+GGR +    A LS  ASD SGWL+LG
Sbjct: 4   SFAITTTFIVYLILMLAIGVYAYQRTKNSADYFLGGRSLGPWPAALSAGASDMSGWLLLG 63

Query: 62  YPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKL 121
            PG A+ AG+ +FW   G L GT A++L+   RLR Y+    ++TLP++L  R  DN+KL
Sbjct: 64  LPGYAYAAGIESFWLAGGLLVGTWANWLVNAKRLRTYSITTDSLTLPEFLSRRFNDNSKL 123

Query: 122 IRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVV 181
           I+ +SA  IL+F   Y ++   AGGK F   F +  +T ++I  + + +Y + GGF AV 
Sbjct: 124 IQTISAFFILLFFLFYTSSGLVAGGKLFETVFGLDYSTAVIIGTVCVVSYTLFGGFLAVS 183

Query: 182 WTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFA-I 240
           WTD+VQ + M   L+I+PI A+   GG  +    +A+++P  L  +  A G      A I
Sbjct: 184 WTDLVQGLLMAAALMIVPIAAM--NGGFTQLNHDLAAINPELLTLWNDAKGEPLSAIAII 241

Query: 241 GYASWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL 297
              +W +GY GQPHI+ R+ +    + L   RR    I+ +WT + + GA   G  G   
Sbjct: 242 SLVAWGLGYFGQPHILARFKASRSNKDLITARR----IAVVWTGLSMAGAILVGLTGLIF 297

Query: 298 VA-SGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIY 356
           V  SG+I ++D E+I   +        +AG ++A I++A+MSTADSQLLV+SSA+A D Y
Sbjct: 298 VTQSGTIGLDDGEKIFMLLVNSLFHPVIAGILLAAILAAIMSTADSQLLVSSSALAEDFY 357

Query: 357 HKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTL 416
            +V   +   + +V + RI V  ++L+A++ A+T    +  +V+ AW G    FGP L L
Sbjct: 358 KQVFKTDASSEDIVRVGRIAVILISLIALFLAMTPDSSVLGLVSYAWAGFGAAFGPALVL 417

Query: 417 SLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINF 476
           SL+W R+ +   + G+  G ++ V+ +    GW                +  VP      
Sbjct: 418 SLYWPRMNRHGALSGIIVGGVTIVVWKQLSGGWF-------------DVYEIVP----GI 460

Query: 477 FVTLFIIIIVSLLTKPPEDVVKLHEELFKKVPIE 510
            ++   I++VSLLT  P++ VK     FKK  IE
Sbjct: 461 ILSTLSIVVVSLLTGEPDEKVKAQHATFKKQLIE 494


>pir||T44298 proline transporter [imported] - Bacillus halodurans
           >gi|4512352|dbj|BAA75317.1| (AB011836) proline
           transporter [Bacillus halodurans]
           >gi|10173274|dbj|BAB04379.1| (AP001509) sodium/proline
           symporter [Bacillus halodurans]
           Length = 501
           
 Score =  321 bits (813), Expect = 2e-86
 Identities = 185/512 (36%), Positives = 280/512 (54%), Gaps = 17/512 (3%)

Query: 1   MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60
           M    L  F++YLV +  IG  A + T     Y +GGR++    A LS  ASD S WL+L
Sbjct: 1   MELATLITFIVYLVGMLVIGLIAYRMTNNLSDYVLGGRRLGGSVAALSAGASDMSSWLLL 60

Query: 61  GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFR-AITLPDYLEARLKDNT 119
           G PG+ +  G+G  W  +G   G   ++  +  RLR Y    + +ITLPD+LE R  D +
Sbjct: 61  GLPGALYVGGMGEIWIAVGLAIGAYLNWQFLAARLRNYTEIAKDSITLPDFLENRFHDKS 120

Query: 120 KLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFA 179
           K++RI+SA +ILVF T Y +A    G   F  +F ++    + I  I++ +Y   GGF A
Sbjct: 121 KILRIVSALVILVFFTFYTSAGLVGGALLFEASFGMTYIQALWIGAIVIISYTFLGGFLA 180

Query: 180 VVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFA 239
           V WTD  Q + M L LII+PI+A+ ++GG       + ++D   L  F GAT    ++  
Sbjct: 181 VSWTDFFQGILMFLALIIVPIVAINKMGGFSETLNAVGAIDTAYLDAFQGAT----VIGV 236

Query: 240 IGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVA 299
               +W +GY GQPHIVTR+M+V+  +++ +   FI   W  + L+GA F GF+G A  +
Sbjct: 237 ASLLAWGLGYFGQPHIVTRFMAVKSLKEIPKAR-FIGMTWMVLALFGAIFTGFVGIAYFS 295

Query: 300 SGS----IKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
           +      I  E  E +           WVAGF++A I+SA+MST DSQLLV+SSA+A D 
Sbjct: 296 ATGPGPEIAGEARETVFILFTQILFDPWVAGFLLAAILSAIMSTIDSQLLVSSSALAEDF 355

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y  +L +   +K++V + R  V  +ALVA+  A      +  +V  AW G    FGP+L 
Sbjct: 356 YKGMLRKNASQKELVWVGRFGVVLIALVAIVLAYNPDSTVLDLVGYAWAGFGAAFGPVLL 415

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFIN 475
           LSL+WKR+T+   + GM  G  + VI+ A++  W FN      +  LG  +  +P F + 
Sbjct: 416 LSLFWKRMTRNGALAGMVVG-GATVIIWAELTNW-FNLSVEQ-YPILG-LYEIIPGFIL- 470

Query: 476 FFVTLFIIIIVSLLTKPPEDVVKLHEELFKKV 507
              ++ II++  L  +PP+++    E+   KV
Sbjct: 471 --ASIAIIVVSRLDQEPPQEIQDEFEKAKTKV 500


>sp|O06493|OPUE_BACSU OSMOREGULATED PROLINE TRANSPORTER (SODIUM/PROLINE SYMPORTER)
           >gi|7442757|pir||H69670 sodium/proline symporter opuE -
           Bacillus subtilis >gi|2114423|gb|AAB66512.1| (U92466)
           osmoregulated proline transporter [Bacillus subtilis]
           >gi|2465556|gb|AAB72182.1| (AF011545) OpuE [Bacillus
           subtilis] >gi|2632980|emb|CAB12486.1| (Z99107) proline
           transporter [Bacillus subtilis]
           Length = 492
           
 Score =  304 bits (771), Expect = 1e-81
 Identities = 162/494 (32%), Positives = 261/494 (52%), Gaps = 22/494 (4%)

Query: 1   MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60
           M+  I+    IY + +  IGW+A K T   + Y +GGR +      LS  A+D SGW+++
Sbjct: 1   MSIEIIISLGIYFIAMLLIGWYAFKKTTDINDYMLGGRGLGPFVTALSAGAADMSGWMLM 60

Query: 61  GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYA-GKFRAITLPDYLEARLKDNT 119
           G PG+ F  GL   W  +G   G  ++YLL+ PRLR Y      AIT+PD+ + R + ++
Sbjct: 61  GVPGAMFATGLSTLWLALGLTIGAYSNYLLLAPRLRAYTEAADDAITIPDFFDKRFQHSS 120

Query: 120 KLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFA 179
            L++I+SA II++F T Y ++   +GG+ F  AF      G+ +T  ++  Y + GGF A
Sbjct: 121 SLLKIVSALIIMIFFTLYTSSGMVSGGRLFESAFGADYKLGLFLTTAVVVLYTLFGGFLA 180

Query: 180 VVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFA 239
           V  TD VQ   M   L+++PI+A   +GG+      I +V+P+ L  F G    A+++  
Sbjct: 181 VSLTDFVQGAIMFAALVLVPIVAFTHVGGVAPTFHEIDAVNPHLLDIFKG----ASVISI 236

Query: 240 IGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVA 299
           I Y +W +GY GQPHI+ R+M+++D + L +P   I   W  I + G+   G +G A   
Sbjct: 237 ISYLAWGLGYYGQPHIIVRFMAIKDIKDL-KPARRIGMSWMIITVLGSVLTGLIGVAYAH 295

Query: 300 SGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKV 359
              + V+DPE I    +       + GF+++ I++A+MS+  SQLLV +SA+  D+Y   
Sbjct: 296 KFGVAVKDPEMIFIIFSKILFHPLITGFLLSAILAAIMSSISSQLLVTASAVTEDLYRSF 355

Query: 360 LGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLW 419
             ++   K++V I R+ V  +A++A+  ++     I  +V  AW G    FGP + LSL+
Sbjct: 356 FRRKASDKELVMIGRLSVLVIAVIAVLLSLNPNSTILDLVGYAWAGFGSAFGPAILLSLY 415

Query: 420 WKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVT 479
           WKR+ +   +  M  G  + +I       W     A            GV      F ++
Sbjct: 416 WKRMNEWGALAAMIVGAATVLI-------WITTGLAKS---------TGVYEIIPGFILS 459

Query: 480 LFIIIIVSLLTKPP 493
           +   IIVS++TK P
Sbjct: 460 MIAGIIVSMITKRP 473


>pir||B81297 sodium/proline symporter Cj1502c [imported] - Campylobacter jejuni
           (strain NCTC 11168) >gi|6968927|emb|CAB73923.1|
           (AL139078) sodium/proline symporter [Campylobacter
           jejuni]
           Length = 495
           
 Score =  303 bits (769), Expect = 2e-81
 Identities = 164/507 (32%), Positives = 265/507 (51%), Gaps = 25/507 (4%)

Query: 1   MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60
           +N  I   F++Y +++ YIG++  K  K  + YF+GGR +  + + LS  ASD SGWL++
Sbjct: 12  INTPIAVMFVVYALLMLYIGFYFYKQNKNSEDYFLGGRTMGPVISALSAGASDMSGWLLM 71

Query: 61  GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKF-RAITLPDYLEARLKDNT 119
           G PG+ + +G    +  IG   G   +++ +  RLRIY      ++T+PDY E R  D+ 
Sbjct: 72  GLPGALYVSGFIDSYIAIGLTIGASLNWIFVAKRLRIYTSVIANSLTIPDYFETRFDDDK 131

Query: 120 KLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFA 179
            ++RI+ A +IL+F T YV++   +G K F   F +     +    II+ AY   GG+ A
Sbjct: 132 HILRIVCAVVILIFFTFYVSSGLVSGAKLFESTFGIRYDYALTTGTIIIVAYTFLGGYKA 191

Query: 180 VVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFA 239
           V WTD++Q + M++ LII+P++ L  +GG   A  I+  + P  L   G   G  +I+ A
Sbjct: 192 VCWTDMIQGLLMMMALIIVPLVMLYHLGGFGEAMNIVREIKPQALS-MGEGVGIVSIISA 250

Query: 240 IGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVA 299
           +   +W +GY GQPHI+ R+MS+   + +     FI   W  + L  A   G LG A V 
Sbjct: 251 L---AWGLGYFGQPHILVRFMSIRSTKDIPM-ATFIGIAWMAVCLLSACMIGILGIAYVH 306

Query: 300 SGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKV 359
              + ++DPE+I   M+      W+AG +++ I++A+MSTA SQLLV+SS IA D Y K+
Sbjct: 307 KFELSLQDPEKIFIVMSQLLFNPWIAGILLSAILAAIMSTASSQLLVSSSTIAEDFYKKI 366

Query: 360 LGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLW 419
             ++     ++N+ ++ V  VA++A   +      +  +V+ AW G    FG ++  SL+
Sbjct: 367 FREDAPSHIVLNLGKLGVLLVAVIAFLISTDKNSSVLSIVSYAWAGFGASFGSVMLFSLF 426

Query: 420 WKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVT 479
           W R+T+   I+GM  G  + V+L             PG                  F V 
Sbjct: 427 WSRMTRVGAILGMITG-AATVVLWKNFANSGLYEIVPG------------------FLVA 467

Query: 480 LFIIIIVSLLTKPPEDVVKLHEELFKK 506
             +III SL T         +E++ K+
Sbjct: 468 SVVIIIASLFTNVRSGTKAAYEKMLKE 494


>dbj|BAB06425.1| (AP001516) proline transporter [Bacillus halodurans]
           Length = 507
           
 Score =  300 bits (759), Expect = 4e-80
 Identities = 178/501 (35%), Positives = 282/501 (55%), Gaps = 17/501 (3%)

Query: 10  LIYLVILAYIGWWANKYTKTE-DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFK 68
           + YLV L  IG  ++K +      +F+ GR ++     LS  +S  S WL+LG  G+A+ 
Sbjct: 13  IAYLVALLLIGLLSSKKSSVGMTDFFIAGRNLNKWTVALSAVSSGRSAWLVLGVTGTAYA 72

Query: 69  AGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAA 128
            GL A WA  G +   +  +  +  R R Y+ +  +IT+PD LE R  D T ++R  SA 
Sbjct: 73  TGLDAVWAVAGYITVEVFLFFYVARRFRAYSEQTGSITIPDILETRFNDKTHILRGGSAF 132

Query: 129 IILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQA 188
           II+ FM AYVA+Q  AGG  FA +  VS +TG+ +T +IL AY + GGF AV  TDVVQA
Sbjct: 133 IIMFFMIAYVASQLVAGGGAFATSMGVSSSTGMWVTAVILLAYTMLGGFHAVSKTDVVQA 192

Query: 189 MFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIVG 248
            FM ++L+I+P++A++ +GG D   Q++ +       PF  A G+ A++  +G      G
Sbjct: 193 GFMFVSLVILPVVAIIGLGGFDPLLQVMHTEGGGFTSPF--AFGFGAVIGLLGIG---FG 247

Query: 249 YLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVASGSIKVE-D 307
             G PHI+ RYMS+++ +++R+  + IS +W  ++ WGA   G  G A     S+    D
Sbjct: 248 SPGNPHILVRYMSLKNVKEMRQAAL-ISSVWNVLMGWGAVMIGLAGRAYFPDVSLLPNGD 306

Query: 308 PERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVL--GQELG 365
            E++   +    L     GF++  +++A+MS+ADSQLLV SSA  RDIY K+    ++L 
Sbjct: 307 QEQVFLMLGSEILHPLFFGFLLVAVLAAIMSSADSQLLVGSSAFVRDIYQKMFRRNRKLS 366

Query: 366 KKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTK 425
           +K++V +SR+       +++  A T  + ++ MV  A+GGL   FGP L LS +WK VT+
Sbjct: 367 QKKLVRLSRLTTVVFMGLSLILAFTAQEFVFWMVLFAFGGLGACFGPALLLSFYWKGVTR 426

Query: 426 EAGIVGMAYGLISEVILEAK-IYGWAFNPKAPGFFGT--LGQWFNGVPVFFINFFVTLFI 482
           +  + GM  GL++ ++++ +  + +AF P       T   G  +  VP     F V   I
Sbjct: 427 QGVLWGMIAGLLTVILVKQQPQWTYAFLPDVKELLNTYFFGITYEAVP----GFIVATTI 482

Query: 483 IIIVSLLTKPPEDVVKLHEEL 503
            +++SL TK P+   ++ E L
Sbjct: 483 TVVISLFTKRPKHAKQIIERL 503


>pir||G64526 sodium/proline symporter - Helicobacter pylori (strain 26695)
           >gi|2313133|gb|AAD07125.1| (AE000527) proline permease
           (putP) [Helicobacter pylori 26695]
           Length = 496
           
 Score =  299 bits (757), Expect = 6e-80
 Identities = 166/501 (33%), Positives = 266/501 (52%), Gaps = 25/501 (4%)

Query: 9   FLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFK 68
           F++Y +++ YIG++  K  +T + YF+G R +  + + LS  ASD SGWL++G PG+ + 
Sbjct: 14  FIVYSLLMLYIGFYFYKQNETTEDYFLGDRSMGPVISALSAGASDMSGWLLMGLPGALYV 73

Query: 69  AGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKF-RAITLPDYLEARLKDNTKLIRILSA 127
            GL      IG   G L +++ +  RLRIY      +IT+ DY E R  D+  ++R++SA
Sbjct: 74  GGLINSHIAIGLSLGALINWVFVAKRLRIYTSVIANSITISDYFETRFSDDKHILRLISA 133

Query: 128 AIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQ 187
            +IL+F   Y+++   +G K F   F +  T  + I  +I+ +Y   GG+ AV WTD++Q
Sbjct: 134 FVILIFFIFYISSGLVSGAKLFEATFGIQYTYALSIGTLIIVSYTFLGGYKAVCWTDLIQ 193

Query: 188 AMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIV 247
            + M+  LI++PI+ ++ +GG+    +II  + P  L    G++    +V  I   +W +
Sbjct: 194 GLLMMSALIVVPIVMIIHLGGIGEGIKIIREIKPENLSFLQGSS----VVAIISSLAWGL 249

Query: 248 GYLGQPHIVTRYMSVEDPRKLRRPGIFISGI-WTTIVLWGAFFAGFLGFALVASGSIKVE 306
           GY GQPHI+ R+MS+   R +  P     GI W  I L GA   G LG A V    + +E
Sbjct: 250 GYFGQPHILVRFMSIRSIRDV--PKATTIGISWMVISLIGACVMGLLGVAYVHKFDLSLE 307

Query: 307 DPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGK 366
           DPE+I   M+      W+ G +++ I++AVMSTA SQLLV+SS IA D Y  +  ++  +
Sbjct: 308 DPEKIFIVMSQLLFNPWITGILLSAILAAVMSTASSQLLVSSSTIAEDFYATIFNKDAPQ 367

Query: 367 KQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTKE 426
           K ++ ISR+ V  VA +A + +      I  +V+ AW G    FG ++  SL+W R+T+ 
Sbjct: 368 KLVMAISRLSVLGVACIAFFISTDRNASILSIVSYAWAGFGASFGSVILFSLFWSRMTRI 427

Query: 427 AGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTLFIIIIV 486
             I GM  G  S VIL                +   G+ F  +      F V    I++ 
Sbjct: 428 GAIAGMLSG-ASTVIL----------------YDKFGKSFLDIYEIVPGFIVASVAIVVF 470

Query: 487 SLLTKPPEDVVKLHEELFKKV 507
           SL +       +  E + K++
Sbjct: 471 SLFSSVRTGTKEAFETMLKEI 491


>pir||A71980 sodium/proline symporter - Helicobacter pylori (strain J99)
           >gi|4154554|gb|AAD05631.1| (AE001444) sodium/proline
           symporter [Helicobacter pylori J99]
           Length = 496
           
 Score =  298 bits (754), Expect = 1e-79
 Identities = 160/445 (35%), Positives = 251/445 (55%), Gaps = 10/445 (2%)

Query: 9   FLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFK 68
           F++Y +++ YIG++  K  +T + YF+G R +  + + LS  ASD SGWL++G PG+ + 
Sbjct: 14  FVVYSLLMLYIGFYFYKQNETTEDYFLGDRSMGPVISALSAGASDMSGWLLMGLPGALYV 73

Query: 69  AGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKF-RAITLPDYLEARLKDNTKLIRILSA 127
            GL      IG   G L +++ +  RLRIY      +IT+ DY E R  D+  ++R++SA
Sbjct: 74  GGLINSHIAIGLSLGALINWVFVAKRLRIYTSVIANSITISDYFETRFSDDKHILRLISA 133

Query: 128 AIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQ 187
            +IL+F   Y+++   +G K F   F +  T  + I  +I+ +Y   GG+ AV WTD++Q
Sbjct: 134 FVILIFFIFYISSGLVSGAKLFEATFGIQYTYALSIGTLIIVSYTFLGGYKAVCWTDLIQ 193

Query: 188 AMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIV 247
            + M+  LI++PI+ ++ +GG+    +II  + P  L    G++    +V  I   +W +
Sbjct: 194 GLLMMSALIVVPIVMIIHLGGIGEGIKIIREIKPENLSFLQGSS----VVAIISSLAWGL 249

Query: 248 GYLGQPHIVTRYMSVEDPRKLRRPGIFISGI-WTTIVLWGAFFAGFLGFALVASGSIKVE 306
           GY GQPHI+ R+MS+   R +  P     GI W  I L GA   G LG A V    + +E
Sbjct: 250 GYFGQPHILVRFMSIRSIRDV--PKATTIGISWMVISLIGACVMGLLGVAYVHKFDLSLE 307

Query: 307 DPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGK 366
           DPE+I   M+      W+ G +++ I++AVMSTA SQLLV+SS IA D Y  +  +   +
Sbjct: 308 DPEKIFIVMSQLLFNPWITGILLSAILAAVMSTASSQLLVSSSTIAEDFYATIFNKNAPQ 367

Query: 367 KQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTKE 426
           K ++ ISR+ V  VA +A + +      I  +V+ AW G    FG ++  SL+W R+T+ 
Sbjct: 368 KLVMTISRLSVLGVACIAFFISTDKNASILSIVSYAWAGFGASFGSVILFSLFWSRMTRI 427

Query: 427 AGIVGMAYGLISEVILEAKIYGWAF 451
             I GM  G  S VIL  K +G +F
Sbjct: 428 GAIAGMLSG-ASTVILYDK-FGKSF 450


>pir||T48676 proline uptake protein [validated] - Staphylococcus aureus
           >gi|2565311|gb|AAC38087.1| (AF024571) high affinity
           proline permease [Staphylococcus aureus]
           Length = 497
           
 Score =  292 bits (740), Expect = 6e-78
 Identities = 170/492 (34%), Positives = 259/492 (52%), Gaps = 31/492 (6%)

Query: 11  IYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAG 70
           +Y +IL  + +   + T    +Y +GGR +      LS  ASD SGW+++G PGS +  G
Sbjct: 24  VYFLILMLLAFTYKQATGNLSEYMLGGRSIGPYITALSAGASDMSGWMIMGLPGSVYSTG 83

Query: 71  LGAFWAGIGCLFGTLADYLLIGPRLRIY---AGKFRAITLPDYLEARLKDNTKLIRILSA 127
           L A W  IG   G   +Y ++ PRLR+Y   AG   AITLPD+ + RL D   +++I+S 
Sbjct: 84  LSAMWITIGLTLGAYINYFVVAPRLRVYTELAGD--AITLPDFFKNRLNDKNNVLKIISG 141

Query: 128 AIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQ 187
            II+VF T Y  + F +GGK F  AF +    G+++   I+  Y   GG+ AV  TD  Q
Sbjct: 142 LIIIVFFTLYTHSGFVSGGKLFESAFGLDYHFGLILVAFIVIFYTFFGGYLAVSITDFFQ 201

Query: 188 AMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIV 247
            + ML+ ++++PI+A++ + G       +A++ P  L+ F G     + +  I   SW +
Sbjct: 202 GVIMLIAMVMVPIVAMMNLNGWG-TFHDVAAMKPTNLNLFKG----LSFIGIISLFSWGL 256

Query: 248 GYLGQPHIVTRYMSVEDPR---KLRRPGIFISGIWTTIVLWGAFFAGFLGFALVASGSIK 304
           GY GQPHI+ R+MS++  +   K RR GI     W  + L GA   G  G A V +  IK
Sbjct: 257 GYFGQPHIIVRFMSIKSHKMLPKARRLGI----SWMAVGLLGAVAVGLTGIAFVPAYHIK 312

Query: 305 VEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQEL 364
           +EDPE +   M+       V GF++A I++A+MST  SQLLV SS++  D Y  + G+E 
Sbjct: 313 LEDPETLFIVMSQVLFHPLVGGFLLAAILAAIMSTISSQLLVTSSSLTEDFYKLIRGEEK 372

Query: 365 GK---KQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWK 421
            K   K+ V I R+ V  VA+VA+  A      I  +V  AW G    F P++  +L+WK
Sbjct: 373 AKTHQKEFVMIGRLSVLVVAIVAIAIAWNPNDTILNLVGNAWAGFGASFSPLVLFALYWK 432

Query: 422 RVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTLF 481
            +T+   + GM  G +  ++  A I   A   +  G +  +             F V++ 
Sbjct: 433 GLTRAGAVSGMVSGALVVIVWIAWIKPLAHINEIFGLYEIIP-----------GFIVSVI 481

Query: 482 IIIIVSLLTKPP 493
           +  +VS LTK P
Sbjct: 482 VTYVVSKLTKKP 493


>gb|AAA79365.1| (U06451) proline permease homolog [Staphylococcus aureus]
           Length = 497
           
 Score =  292 bits (739), Expect = 8e-78
 Identities = 170/492 (34%), Positives = 259/492 (52%), Gaps = 31/492 (6%)

Query: 11  IYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAG 70
           +Y +IL  + +   + T    +Y +GGR +      LS  ASD SGW+++G PGS +  G
Sbjct: 24  VYFLILMLLAFTYKQATGNLSEYMLGGRSIGPYITALSAGASDMSGWMIMGLPGSVYSTG 83

Query: 71  LGAFWAGIGCLFGTLADYLLIGPRLRIY---AGKFRAITLPDYLEARLKDNTKLIRILSA 127
           L A W  IG   G   +Y ++ PRLR+Y   AG   AITLPD+ + RL D   +++I+S 
Sbjct: 84  LSAMWITIGLTLGAYINYFVVAPRLRVYTELAGD--AITLPDFFKNRLNDKNNVLKIISG 141

Query: 128 AIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQ 187
            II+VF T Y  + F +GGK F  AF +    G+++   I+  Y   GG+ AV  TD  Q
Sbjct: 142 LIIVVFFTLYTHSGFVSGGKLFESAFGLDYHFGLILVAFIVIFYTFFGGYLAVSITDFFQ 201

Query: 188 AMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIV 247
            + ML+ ++++PI+A++ + G       +A++ P  L+ F G     + +  I   SW +
Sbjct: 202 GVIMLIAMVMVPIVAMMNLNGWG-TFHDVAAMKPTNLNLFKG----LSFIGIISLFSWGL 256

Query: 248 GYLGQPHIVTRYMSVEDPR---KLRRPGIFISGIWTTIVLWGAFFAGFLGFALVASGSIK 304
           GY GQPHI+ R+MS++  +   K RR GI     W  + L GA   G  G A V +  IK
Sbjct: 257 GYFGQPHIIVRFMSIKSHKMLPKARRLGI----SWMAVGLLGAVAVGLTGIAFVPAYHIK 312

Query: 305 VEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQEL 364
           +EDPE +   M+       V GF++A I++A+MST  SQLLV SS++  D Y  + G+E 
Sbjct: 313 LEDPETLFIVMSQVLFHPLVGGFLLAAILAAIMSTISSQLLVTSSSLTEDFYKLIRGEEK 372

Query: 365 GK---KQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWK 421
            K   K+ V I R+ V  VA+VA+  A      I  +V  AW G    F P++  +L+WK
Sbjct: 373 AKTDQKEFVMIGRLSVLVVAIVAIAIAWNPNDTILNLVGNAWAGFGASFSPLVLFALYWK 432

Query: 422 RVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTLF 481
            +T+   + GM  G +  ++  A I   A   +  G +  +             F V++ 
Sbjct: 433 GLTRAGAVSGMVSGALVVIVWIAWIKPLAHINEIFGLYEIIP-----------GFIVSVI 481

Query: 482 IIIIVSLLTKPP 493
           +  +VS LTK P
Sbjct: 482 VTYVVSKLTKKP 493


>pir||F83547 sodium/proline symporter PutP PA0783 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9946673|gb|AAG04172.1|AE004513_4 (AE004513)
           sodium/proline symporter PutP [Pseudomonas aeruginosa]
           Length = 506
           
 Score =  291 bits (736), Expect = 2e-77
 Identities = 170/502 (33%), Positives = 251/502 (49%), Gaps = 36/502 (7%)

Query: 1   MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60
           +N   L  F+IY+  +  IG  A + T     Y +GGR +      LS  ASD SGWL++
Sbjct: 3   VNTPTLITFVIYIAAMVLIGLAAYRSTNNFSDYILGGRSLGSFVTALSAGASDMSGWLLM 62

Query: 61  GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNT 119
           G PG+ + +GL   W  IG + G   ++L +  RLR+       A+TLPDY   R +DN+
Sbjct: 63  GLPGAVYLSGLSESWIAIGLIVGAYLNWLFVAGRLRVQTEHNGNALTLPDYFTNRFEDNS 122

Query: 120 KLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFA 179
           +L+RI SA +ILVF T Y A+   AG + F   F +S  T +        AY   GGF A
Sbjct: 123 RLLRIFSALVILVFFTIYCASGIVAGARLFESTFGLSYETALWAGAAATIAYTFIGGFLA 182

Query: 180 VVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFA 239
           V WTD VQA  M+  LI+ P++ ++  GG++     I   D        GA+     +  
Sbjct: 183 VSWTDTVQASLMIFALILTPVIVMLATGGVEPTFTAIELKDATSFDMLKGAS----FIGV 238

Query: 240 IGYASWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFA 296
           I   +W +GY GQPHI+ R+M+ +  + +   RR    IS  W  + L GA   GF G A
Sbjct: 239 ISLMAWGLGYFGQPHILARFMAADSVKSIPAARR----ISMTWMILCLGGAVAVGFFGIA 294

Query: 297 LVAS-----GSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAI 351
              +     G++  E+PER+   +A      W+AG +++ I++AVMST   QLLV SSA+
Sbjct: 295 YFQAHPEQAGAVS-ENPERVFIELAKILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSAL 353

Query: 352 ARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFG 411
             D Y   L +   + ++V + R +V  VA++A+W A      +  +V+ AW G    FG
Sbjct: 354 TEDFYKAFLRKGASQLELVWVGRAMVLLVAVIAIWLASNPENRVLGLVSYAWAGFGAAFG 413

Query: 412 PILTLSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPV 471
           P++  SL WKR+T+   + GM  G  + VIL   + GW                  G+  
Sbjct: 414 PLVLFSLLWKRMTRNGALAGMIVG-AATVILWKNLLGW-----------------TGLYE 455

Query: 472 FFINFFVTLFIIIIVSLLTKPP 493
               F      I++ SLL K P
Sbjct: 456 IIPGFLFASVAIVVFSLLGKAP 477


>gb|AAA99282.1| (L01140) proline permease [Salmonella sp.]
           >gi|154302|gb|AAA99283.1| (L01141) proline permease
           [Salmonella sp.]
           Length = 489
           
 Score =  290 bits (734), Expect = 3e-77
 Identities = 169/500 (33%), Positives = 261/500 (51%), Gaps = 41/500 (8%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F +Y+  +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFCVYIFGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123
           + F +G+   W  IG   G   ++ L+  RLR++      A+TLPDY  +R +D ++++R
Sbjct: 67  AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTSRFEDKSRVLR 126

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           I+SA +IL+F T Y A+   AG + F   F +S  T +         Y   GGF AV WT
Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243
           D VQA  M+  LI+ P++ +V +GG   + ++I       +    G   + AI+  +G  
Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243

Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297
            W +GY GQPHI+ R+M+ +    +   RR    IS  W  + L GA   GF G A    
Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLTGAVAVGFFGIAFFNN 298

Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
               +G++  ++ ER+   +A      W+AG +++ I++AVMST   QLLV SSAI  D+
Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSAITEDL 357

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y   L +  G++++V + R++V  VAL+A+  A      +  +V+ AW G    FGP++ 
Sbjct: 358 YKAFLRKSAGQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLGQWFNGVPVFF 473
            S+ W R+T+   + GM  G ++ ++   K YGW       PGF FG++G          
Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSIG---------- 465

Query: 474 INFFVTLFIIIIVSLLTKPP 493
                    I+I SLL K P
Sbjct: 466 ---------IVIFSLLGKAP 476


>gb|AAA24465.1| (L01152) proline permease [Escherichia coli]
           Length = 489
           
 Score =  289 bits (731), Expect = 7e-77
 Identities = 162/470 (34%), Positives = 252/470 (53%), Gaps = 22/470 (4%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F +Y+  +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123
           + F +G+   W  IG   G   ++ L+  RLR++      A+TLPDY   R +D ++++R
Sbjct: 67  AVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILR 126

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           I+SA +IL+F T Y A+   AG + F   F +S  T +   V     Y   GGF AV WT
Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGVAATILYTFIGGFLAVSWT 186

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243
           D VQA  M+  LI+ P++ ++ +GG   + ++I       +    G   + AI+  +G  
Sbjct: 187 DTVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243

Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297
            W +GY GQPHI+ R+M+ +    +   RR    IS  W  + L GA   GF G A    
Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNE 298

Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
               +G++  ++ ER+   +A      W+AG +++ I++AVMST   QLLV SSAI  D+
Sbjct: 299 HPAVAGAVN-QNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y   L +   +K++V + R++V  VALVA+  A      +  +V+ AW G    FGP++ 
Sbjct: 358 YKAFLRKHASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVL 417

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGW-AFNPKAPGF-FGTLG 463
            S+ W R+T+   + GM  G ++ ++   K +GW       PGF FG++G
Sbjct: 418 FSVMWSRMTRNGALAGMIIGALTVIVW--KQFGWLGLYEIIPGFIFGSIG 465


>gb|AAA24461.1| (L01132) proline permease [Escherichia coli]
           >gi|147447|gb|AAA24467.1| (L01154) proline permease
           [Escherichia coli] >gi|147451|gb|AAA24469.1| (L01156)
           proline permease [Escherichia coli]
           Length = 489
           
 Score =  288 bits (729), Expect = 1e-76
 Identities = 161/470 (34%), Positives = 252/470 (53%), Gaps = 22/470 (4%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F +Y+  +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123
           + F +G+   W  IG   G   ++ L+  RLR++      A+TLPDY   R +D ++++R
Sbjct: 67  AVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILR 126

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           I+SA +IL+F T Y A+   AG + F   F +S  T +         Y   GGF AV WT
Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGFLAVSWT 186

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243
           D VQA  M+  LI+ P++ ++ +GG   + ++I       +    G   + AI+  +G  
Sbjct: 187 DTVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243

Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297
            W +GY GQPHI+ R+M+ +    +   RR    IS  W  + L GA   GF G A    
Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNE 298

Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
               +G++  ++ ER+   +A      W+AG +++ I++AVMST   QLLV SSAI  D+
Sbjct: 299 HPAVAGAVN-QNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y   L ++  +K++V + R++V  VALVA+  A      +  +V+ AW G    FGP++ 
Sbjct: 358 YKAFLRKQASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVL 417

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGW-AFNPKAPGF-FGTLG 463
            S+ W R+T+   + GM  G ++ ++   K +GW       PGF FG++G
Sbjct: 418 FSVMWSRMTRNGALAGMIIGALTVIVW--KQFGWLGLYEIIPGFIFGSIG 465


>gb|AAA99281.1| (L01139) proline permease [Salmonella sp.]
           Length = 489
           
 Score =  287 bits (728), Expect = 2e-76
 Identities = 167/505 (33%), Positives = 262/505 (51%), Gaps = 41/505 (8%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F +Y++ +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFCVYILGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123
           + F +G+   W  IG   G   ++ L+  RLR++      A+TLPDY   R +D ++++R
Sbjct: 67  AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           I+SA +IL+F T Y A+   AG + F   F +S  T +         Y   GGF AV WT
Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243
           D VQA  M+  LI+ P++ +V +GG   + ++I       +    G   + AI+  +G  
Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKG-LNFVAIISLMG-- 243

Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297
            W +GY GQPHI+ R+M+ +    +   RR    IS  W  + L GA   GF G A    
Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298

Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
               +G++  ++ ER+   +A      W+AG +++ I++AVMST   QLLV SSAI  D+
Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y   L +   ++++V + R++V  VAL+A+  A      +  +V+ AW G    FGP++ 
Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLGQWFNGVPVFF 473
            S+ W R+T+   + GM  G ++ ++   K YGW       PGF FG++G          
Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSMG---------- 465

Query: 474 INFFVTLFIIIIVSLLTKPPEDVVK 498
                    I++ SLL K P   ++
Sbjct: 466 ---------IVVFSLLGKAPTAAIQ 481


>gb|AAA99284.1| (L01142) proline permease [Salmonella sp.]
           >gi|154306|gb|AAA99285.1| (L01143) proline permease
           [Salmonella sp.]
           Length = 489
           
 Score =  287 bits (728), Expect = 2e-76
 Identities = 163/470 (34%), Positives = 252/470 (52%), Gaps = 22/470 (4%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F +Y++ +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFCVYILGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123
           + F +G+   W  IG   G   ++ L+  RLR++      A+TLPDY   R +D ++++R
Sbjct: 67  AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           I+SA +IL+F T Y A+   AG + F   F +S  T +         Y   GGF AV WT
Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243
           D VQA  M+  LI+ P++ +V +GG   + ++I       +    G   + AI+  +G  
Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243

Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297
            W +GY GQPHI+ R+M+ +    +   RR    IS  W  + L GA   GF G A    
Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298

Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
               +G++  ++ ER+   +A      WVAG +++ I++AVMST   QLLV SSAI  D+
Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWVAGVLLSAILAAVMSTLSCQLLVCSSAITEDL 357

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y   L +   ++++V + R++V  VALVA+  A      +  +V+ AW G    FGP++ 
Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALVAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLG 463
            S+ W R+T+   + GM  G ++ ++   K YGW       PGF FG++G
Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSMG 465


>gb|AAA99286.1| (L01144) proline permease [Salmonella sp.]
           >gi|154310|gb|AAA99287.1| (L01145) proline permease
           [Salmonella sp.]
           Length = 489
           
 Score =  287 bits (728), Expect = 2e-76
 Identities = 162/470 (34%), Positives = 252/470 (53%), Gaps = 22/470 (4%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F +Y++ +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFCVYILGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123
           + F +G+   W  IG   G   ++ L+  RLR++      A+TLPDY   R +D ++++R
Sbjct: 67  AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           I+SA +IL+F T Y A+   AG + F   F +S  T +         Y   GGF AV WT
Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243
           D VQA  M+  LI+ P++ +V +GG   + ++I       +    G   + AI+  +G  
Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243

Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297
            W +GY GQPHI+ R+M+ +    +   RR    IS  W  + L GA   GF G A    
Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298

Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
               +G++  ++ ER+   +A      W+AG +++ I++AVMST   QLLV SSAI  D+
Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y   L +   ++++V + R++V  VALVA+  A      +  +V+ AW G    FGP++ 
Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALVAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLG 463
            S+ W R+T+   + GM  G ++ ++   K YGW       PGF FG++G
Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSMG 465


>sp|P10502|PUTP_SALTY SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)
           >gi|47849|emb|CAA36802.1| (X52573) proline permease (AA
           1-502) [Salmonella typhimurium]
           Length = 502
           
 Score =  287 bits (727), Expect = 2e-76
 Identities = 169/500 (33%), Positives = 259/500 (51%), Gaps = 41/500 (8%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F +Y+  +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123
           + F +G+   W  IG   G   ++ L+  RLR++      A+TLPDY   R +D ++++R
Sbjct: 67  AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           I+SA +IL+F T Y A+   AG + F   F +S  T +         Y   GGF AV WT
Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243
           D VQA  M+  LI+ P++ +V +GG   + ++I       +    G   + AI+  +G  
Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKG-LNFVAIISLMG-- 243

Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297
            W +GY GQPHI+ R+M+ +    +   RR    IS  W  + L GA   GF G A    
Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298

Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
               +G++  ++ ER+   +A      W+AG +++ I++AVMST   QLLV SSAI  D+
Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSAITEDL 357

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y   L +   ++++V + R++V  VAL+A+  A      +  +V+ AW G    FGP++ 
Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLGQWFNGVPVFF 473
            S+ W R+T+   + GM  G ++ ++   K YGW       PGF FG+LG          
Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSLG---------- 465

Query: 474 INFFVTLFIIIIVSLLTKPP 493
                    I+I SLL K P
Sbjct: 466 ---------IVIFSLLGKAP 476


>gb|AAA27199.1| (L01135) proline permease [Salmonella typhimurium]
           Length = 489
           
 Score =  287 bits (727), Expect = 2e-76
 Identities = 169/500 (33%), Positives = 259/500 (51%), Gaps = 41/500 (8%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F +Y+  +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123
           + F +G+   W  IG   G   ++ L+  RLR++      A+TLPDY   R +D ++++R
Sbjct: 67  AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           I+SA +IL+F T Y A+   AG + F   F +S  T +         Y   GGF AV WT
Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243
           D VQA  M+  LI+ P++ +V +GG   + ++I       +    G   + AI+  +G  
Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKG-LNFVAIISLMG-- 243

Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297
            W +GY GQPHI+ R+M+ +    +   RR    IS  W  + L GA   GF G A    
Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298

Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
               +G++  ++ ER+   +A      W+AG +++ I++AVMST   QLLV SSAI  D+
Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSAITEDL 357

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y   L +   ++++V + R++V  VAL+A+  A      +  +V+ AW G    FGP++ 
Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLGQWFNGVPVFF 473
            S+ W R+T+   + GM  G ++ ++   K YGW       PGF FG+LG          
Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSLG---------- 465

Query: 474 INFFVTLFIIIIVSLLTKPP 493
                    I+I SLL K P
Sbjct: 466 ---------IVIFSLLGKAP 476


>gb|AAA26389.1| (L01134) proline permease [Rickettsia typhi]
           Length = 489
           
 Score =  287 bits (727), Expect = 2e-76
 Identities = 169/500 (33%), Positives = 259/500 (51%), Gaps = 41/500 (8%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F +Y+  +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123
           + F +G+   W  IG   G   ++ L+  RLR++      A+TLPDY   R +D ++++R
Sbjct: 67  AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           I+SA +IL+F T Y A+   AG + F   F +S  T +         Y   GGF AV WT
Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243
           D VQA  M+  LI+ P++ +V +GG   + ++I       +    G   + AI+  +G  
Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKG-LNFVAIISLMG-- 243

Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297
            W +GY GQPHI+ R+M+ +    +   RR    IS  W  + L GA   GF G A    
Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298

Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
               +G++  ++ ER+   +A      W+AG +++ I++AVMST   QLLV SSAI  D+
Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSAITEDL 357

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y   L +   ++++V + R++V  VAL+A+  A      +  +V+ AW G    FGP++ 
Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLGQWFNGVPVFF 473
            S+ W R+T+   + GM  G ++ ++   K YGW       PGF FG+LG          
Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSLG---------- 465

Query: 474 INFFVTLFIIIIVSLLTKPP 493
                    I+I SLL K P
Sbjct: 466 ---------IVIFSLLGKAP 476


>gb|AAA24466.1| (L01153) proline permease [Escherichia coli]
           >gi|147453|gb|AAA24470.1| (L01157) proline permease
           [Escherichia coli] >gi|147455|gb|AAA24471.1| (L01158)
           proline permease [Escherichia coli]
           >gi|147457|gb|AAA24472.1| (L01159) proline permease
           [Escherichia coli]
           Length = 489
           
 Score =  287 bits (727), Expect = 2e-76
 Identities = 161/470 (34%), Positives = 251/470 (53%), Gaps = 22/470 (4%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F +Y+  +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123
           + F +G+   W  IG   G   ++ L+  RLR++      A+TLPDY   R +D ++++R
Sbjct: 67  AVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILR 126

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           I+SA +IL+F T Y A+   AG + F   F +S  T +         Y   GGF AV WT
Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGFLAVSWT 186

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243
           D VQA  M+  LI+ P++ ++ +GG   + ++I       +    G   + AI+  +G  
Sbjct: 187 DTVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243

Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297
            W +GY GQPHI+ R+M+ +    +   RR    IS  W  + L GA   GF G A    
Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNE 298

Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
               +G++  ++ ER+   +A      W+AG +++ I++AVMST   QLLV SSAI  D+
Sbjct: 299 HPAVAGAVN-QNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y   L +   +K++V + R++V  VALVA+  A      +  +V+ AW G    FGP++ 
Sbjct: 358 YKAFLRKHASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVL 417

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGW-AFNPKAPGF-FGTLG 463
            S+ W R+T+   + GM  G ++ ++   K +GW       PGF FG++G
Sbjct: 418 FSVMWSRMTRNGALAGMIIGALTVIVW--KQFGWLGLYEIIPGFIFGSIG 465


>sp|P07117|PUTP_ECOLI SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE) >gi|72512|pir||JGECPP
           sodium/proline symporter - Escherichia coli
           >gi|42602|emb|CAA29143.1| (X05653) putP proline carrier
           (AA 1-502) [Escherichia coli]
           >gi|1651504|dbj|BAA35793.1| (D90738) Proline carrier
           protein [Escherichia coli] >gi|1787251|gb|AAC74100.1|
           (AE000203) major sodium/proline symporter [Escherichia
           coli K12] >gi|225963|prf||1404369A Pro carrier protein
           [Escherichia coli]
           Length = 502
           
 Score =  287 bits (726), Expect = 3e-76
 Identities = 161/470 (34%), Positives = 251/470 (53%), Gaps = 22/470 (4%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F +Y+  +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123
           + F +G+   W  IG   G   ++ L+  RLR++      A+TLPDY   R +D ++++R
Sbjct: 67  AVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILR 126

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           I+SA +IL+F T Y A+   AG + F   F +S  T +         Y   GGF AV WT
Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGFLAVSWT 186

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243
           D VQA  M+  LI+ P++ ++ +GG   + ++I       +    G   + AI+  +G  
Sbjct: 187 DTVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243

Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297
            W +GY GQPHI+ R+M+ +    +   RR    IS  W  + L GA   GF G A    
Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFND 298

Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
               +G++  ++ ER+   +A      W+AG +++ I++AVMST   QLLV SSAI  D+
Sbjct: 299 HPALAGAVN-QNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y   L +   +K++V + R++V  VALVA+  A      +  +V+ AW G    FGP++ 
Sbjct: 358 YKAFLRKHASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVL 417

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGW-AFNPKAPGF-FGTLG 463
            S+ W R+T+   + GM  G ++ ++   K +GW       PGF FG++G
Sbjct: 418 FSVMWSRMTRNGALAGMIIGALTVIVW--KQFGWLGLYEIIPGFIFGSIG 465


>gb|AAA24463.1| (L01150) proline permease [Escherichia coli]
           >gi|147441|gb|AAA24464.1| (L01151) proline permease
           [Escherichia coli]
           Length = 489
           
 Score =  287 bits (726), Expect = 3e-76
 Identities = 161/470 (34%), Positives = 251/470 (53%), Gaps = 22/470 (4%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F +Y+  +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123
           + F +G+   W  IG   G   ++ L+  RLR++      A+TLPDY   R +D ++++R
Sbjct: 67  AVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILR 126

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           I+SA +IL+F T Y A+   AG + F   F +S  T +         Y   GGF AV WT
Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGFLAVSWT 186

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243
           D VQA  M+  LI+ P++ ++ +GG   + ++I       +    G   + AI+  +G  
Sbjct: 187 DTVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243

Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297
            W +GY GQPHI+ R+M+ +    +   RR    IS  W  + L GA   GF G A    
Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFND 298

Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
               +G++  ++ ER+   +A      W+AG +++ I++AVMST   QLLV SSAI  D+
Sbjct: 299 HPALAGAVN-QNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y   L +   +K++V + R++V  VALVA+  A      +  +V+ AW G    FGP++ 
Sbjct: 358 YKAFLRKHASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVL 417

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGW-AFNPKAPGF-FGTLG 463
            S+ W R+T+   + GM  G ++ ++   K +GW       PGF FG++G
Sbjct: 418 FSVMWSRMTRNGALAGMIIGALTVIVW--KQFGWLGLYEIIPGFIFGSIG 465


>gb|AAA99278.1| (L01136) proline permease [Salmonella sp.]
           Length = 489
           
 Score =  287 bits (726), Expect = 3e-76
 Identities = 169/500 (33%), Positives = 259/500 (51%), Gaps = 41/500 (8%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F +Y+  +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFCVYIFGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123
           + F +G+   W  IG   G   ++ L+  RLR++      A+TLPDY   R +D ++++R
Sbjct: 67  AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           I+SA +IL+F T Y A+   AG + F   F +S  T +         Y   GGF AV WT
Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243
           D VQA  M+  LI+ P++ +V +GG   + ++I       +    G   + AI+  +G  
Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKG-LNFVAIISLMG-- 243

Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297
            W +GY GQPHI+ R+M+ +    +   RR    IS  W  + L GA   GF G A    
Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298

Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
               +G++  ++ ER+   +A      WVAG +++ I++AVMST   QLLV SSAI  D+
Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWVAGVLLSAILAAVMSTLSCQLLVCSSAITEDL 357

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y   L +   ++++V + R++V  VAL+A+  A      +  +V+ AW G    FGP++ 
Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLGQWFNGVPVFF 473
            S+ W R+T+   + GM  G ++ ++   K YGW       PGF FG++G          
Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSIG---------- 465

Query: 474 INFFVTLFIIIIVSLLTKPP 493
                    I+I SLL K P
Sbjct: 466 ---------IVIFSLLGKAP 476


>gb|AAA24462.1| (L01133) proline permease [Escherichia coli]
           Length = 489
           
 Score =  287 bits (726), Expect = 3e-76
 Identities = 161/470 (34%), Positives = 251/470 (53%), Gaps = 22/470 (4%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F +Y+  +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123
           + F +G+   W  IG   G   ++ L+  RLR++      A+TLPDY   R +D ++++R
Sbjct: 67  AVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILR 126

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           I+SA +IL+F T Y A+   AG + F   F +S  T +         Y   GGF AV WT
Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGFLAVSWT 186

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243
           D VQA  M+  LI+ P++ ++ +GG   + ++I       +    G   + AI+  +G  
Sbjct: 187 DTVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243

Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFALV-- 298
            W +GY GQPHI+ R+M+ +    +   RR    IS  W  + L GA   GF G A    
Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNE 298

Query: 299 ---ASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
               +G++  ++ ER+   +A      W+AG +++ I++AVMST   QLLV SSAI  D+
Sbjct: 299 HPSVAGAVN-QNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y   L +   +K++V + R++V  VALVA+  A      +  +V+ AW G    FGP++ 
Sbjct: 358 YKAFLRKHASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVL 417

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGW-AFNPKAPGF-FGTLG 463
            S+ W R+T+   + GM  G ++ ++   K +GW       PGF FG++G
Sbjct: 418 FSVMWSRMTRNGALAGMIIGALTVIVW--KQFGWLGLYEIIPGFIFGSIG 465


>gb|AAA99279.1| (L01137) proline permease [Salmonella sp.]
           Length = 489
           
 Score =  287 bits (726), Expect = 3e-76
 Identities = 169/500 (33%), Positives = 259/500 (51%), Gaps = 41/500 (8%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F +Y+  +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFCVYIFGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123
           + F +G+   W  IG   G   ++ L+  RLR++      A+TLPDY   R +D ++++R
Sbjct: 67  AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           I+SA +IL+F T Y A+   AG + F   F +S  T +         Y   GGF AV WT
Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243
           D VQA  M+  LI+ P++ +V +GG   + ++I       +    G   + AI+  +G  
Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKG-LNFVAIISLMG-- 243

Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297
            W +GY GQPHI+ R+M+ +    +   RR    IS  W  + L GA   GF G A    
Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298

Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
               +G++  ++ ER+   +A      WVAG +++ I++AVMST   QLLV SSAI  D+
Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWVAGVLLSAILAAVMSTLSCQLLVCSSAITEDL 357

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y   L +   ++++V + R++V  VAL+A+  A      +  +V+ AW G    FGP++ 
Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLGQWFNGVPVFF 473
            S+ W R+T+   + GM  G ++ ++   K YGW       PGF FG++G          
Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSIG---------- 465

Query: 474 INFFVTLFIIIIVSLLTKPP 493
                    I+I SLL K P
Sbjct: 466 ---------IVIFSLLGKAP 476


>gb|AAA99280.1| (L01138) proline permease [Salmonella sp.]
           Length = 489
           
 Score =  287 bits (726), Expect = 3e-76
 Identities = 167/505 (33%), Positives = 262/505 (51%), Gaps = 41/505 (8%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F +Y++ +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFCVYILGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123
           + F +G+   W  IG   G   ++ L+  RLR++      A+TLPDY   R +D ++++R
Sbjct: 67  AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           I+SA +IL+F T Y A+   AG + F   F +S  T +         Y   GGF AV WT
Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243
           D VQA  M+  LI+ P++ +V +GG   + ++I       +    G   + AI+  +G  
Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKG-LNFVAIISLMG-- 243

Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297
            W +GY GQPHI+ R+M+ +    +   RR    IS  W  + L GA   GF G A    
Sbjct: 244 -WGLGYFGQPHILARFMAADSHYSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298

Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
               +G++  ++ ER+   +A      W+AG +++ I++AVMST   QLLV SSAI  D+
Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y   L +   ++++V + R++V  VAL+A+  A      +  +V+ AW G    FGP++ 
Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLGQWFNGVPVFF 473
            S+ W R+T+   + GM  G ++ ++   K YGW       PGF FG++G          
Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSMG---------- 465

Query: 474 INFFVTLFIIIIVSLLTKPPEDVVK 498
                    I++ SLL K P   ++
Sbjct: 466 ---------IVVFSLLGKAPTAAIQ 481


>gb|AAA24468.1| (L01155) proline permease [Escherichia coli]
           Length = 489
           
 Score =  286 bits (725), Expect = 3e-76
 Identities = 160/470 (34%), Positives = 251/470 (53%), Gaps = 22/470 (4%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F +Y+  +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123
           + F +G+   W  IG   G   ++ L+  RLR++      A+TLPDY   R +D ++++R
Sbjct: 67  AVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILR 126

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           I+SA +IL+F T Y A+   AG + F   F +S  T +         Y   GGF AV WT
Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGFLAVSWT 186

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243
           D VQA  M+  LI+ P++ ++ +GG   + ++I       +    G   + AI+  +G  
Sbjct: 187 DTVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243

Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297
            W +GY GQPHI+ R+M+ +    +   RR    IS  W  + L GA   GF G A    
Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNE 298

Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
               +G++  ++ ER+   +A      W+AG +++ I++AVMST   QLLV SSAI  D+
Sbjct: 299 HPAVAGAVN-QNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y   + +   +K++V + R++V  VALVA+  A      +  +V+ AW G    FGP++ 
Sbjct: 358 YKAFMRKHASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVL 417

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGW-AFNPKAPGF-FGTLG 463
            S+ W R+T+   + GM  G ++ ++   K +GW       PGF FG++G
Sbjct: 418 FSVMWSRMTRNGALAGMIIGALTVIVW--KQFGWLGLYEIIPGFIFGSIG 465


>pir||JC2382 sodium/proline symporter - Pseudomonas fluorescens
           >gi|509694|dbj|BAA06838.1| (D32069) proline permease
           [Pseudomonas fluorescens] >gi|913690|gb|AAC60490.1|
           (S76070) proline permease [Pseudomonas fluorescens,
           Peptide, 494 aa] >gi|1092517|prf||2024229A Pro permease
           [Pseudomonas fluorescens]
           Length = 494
           
 Score =  286 bits (724), Expect = 5e-76
 Identities = 158/444 (35%), Positives = 233/444 (51%), Gaps = 16/444 (3%)

Query: 6   LFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65
           L  F+IY+  +  IG  A + T     Y +GGR +  +   LS  ASD SGWL++G PG+
Sbjct: 8   LITFVIYIAAMVLIGLMAYRSTNNLSDYILGGRSLGSVVTALSAGASDMSGWLLMGLPGA 67

Query: 66  AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIRI 124
            + +GL   W  IG + G   ++L +  RLR+       A+TLPDY  +R +D + L+RI
Sbjct: 68  IYMSGLSESWIAIGLIVGAYLNWLFVAGRLRVQTEHNGDALTLPDYFSSRFEDKSGLLRI 127

Query: 125 LSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTD 184
           +SA +ILVF T Y A+   AG + F   F +S  T +        AY   GGF AV WTD
Sbjct: 128 ISAVVILVFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIAYTFIGGFLAVSWTD 187

Query: 185 VVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYAS 244
            VQA  M+  LI+ PI+ L+  GG+D     I + DP         T     +  I    
Sbjct: 188 TVQATLMIFALILTPIIVLLATGGVDTTFLAIEAKDPTSFDMLKNTT----FIGIISLMG 243

Query: 245 WIVGYLGQPHIVTRYM---SVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVAS- 300
           W +GY GQPHI+ R+M   SV+   K RR    IS  W  + L G    GF G A  ++ 
Sbjct: 244 WGLGYFGQPHILARFMAADSVKSIAKARR----ISMTWMILCLGGTVAVGFFGIAYFSAH 299

Query: 301 ---GSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYH 357
                   E+PER+   +A      WVAG +++ I++AVMST   QLLV SSA+  D Y 
Sbjct: 300 PEVAGPVTENPERVFIELAKILFNPWVAGVLLSAILAAVMSTLSCQLLVCSSALTEDFYK 359

Query: 358 KVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLS 417
             L +   ++++V + R++V  VAL+A+  A      +  +V+ AW G    FGP++ +S
Sbjct: 360 AFLRKGASQRELVWVGRLMVLVVALIAIAMAANPENRVLGLVSYAWAGFGAAFGPVVLIS 419

Query: 418 LWWKRVTKEAGIVGMAYGLISEVI 441
           + WK +T+   + G+  G I+ ++
Sbjct: 420 VIWKHMTRNGALAGILVGAITVIV 443


>gb|AAA99288.1| (L01146) proline permease [Salmonella sp.]
           >gi|154314|gb|AAA99289.1| (L01147) proline permease
           [Salmonella sp.]
           Length = 489
           
 Score =  286 bits (724), Expect = 5e-76
 Identities = 161/470 (34%), Positives = 251/470 (53%), Gaps = 22/470 (4%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F +Y+  +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123
           + F +G+   W  IG   G   ++ L+  RLR++      A+TLPDY   R +D ++++R
Sbjct: 67  AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           I+SA +IL+F T Y A+   AG + F   F +S  T +         Y   GGF AV WT
Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243
           D VQA  M+  LI+ P++ +V +GG   + ++I       +    G   + AI+  +G  
Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKG-LNFVAIISLMG-- 243

Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297
            W +GY GQPHI+ R+M+ +    +   RR    IS  W  + L GA   GF G A    
Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298

Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
               +G++  ++ ER+   +A      W+AG +++ I++AVMST   QLLV SSAI  D+
Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y   L +   ++++V + R++V  VAL+A+  A      +  +V+ AW G    FGP++ 
Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPNNRVLGLVSYAWAGFGAAFGPVVL 417

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGW-AFNPKAPGF-FGTLG 463
            S+ W R+T+   + GM  G ++ ++   K YGW       PGF FG++G
Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLELYEIIPGFIFGSIG 465


>gb|AAA99291.1| (L01149) proline permease [Salmonella sp.]
           Length = 489
           
 Score =  286 bits (723), Expect = 6e-76
 Identities = 161/470 (34%), Positives = 250/470 (52%), Gaps = 22/470 (4%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F +Y+  +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123
           + F +G+   W  IG   G   ++ L+  RLR++      A+TLPDY   R +D ++++R
Sbjct: 67  AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           I+SA +IL+F T Y A+   AG + F   F +S  T +         Y   GGF AV WT
Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243
           D VQA  M+  LI+ P++ +V +GG   + ++I       +    G   + AI+  +G  
Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKG-LNFVAIISLMG-- 243

Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297
            W +GY GQPHI+ R+M+ +    +   RR    IS  W  + L GA   GF G A    
Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298

Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
               +G++  ++ ER+   +A      W+AG +++ I++AVMST   QLLV SSAI  D+
Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSAITEDL 357

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y   L +   ++++V + R++V  VAL+A+  A      +  +V  AW G    FGP++ 
Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVTYAWAGFGAAFGPVVL 417

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLG 463
            S+ W R+T+   + GM  G ++ ++   K YGW       PGF FG++G
Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSIG 465


>pir||S10220 sodium/proline symporter - Salmonella typhimurium
           Length = 502
           
 Score =  284 bits (720), Expect = 1e-75
 Identities = 160/470 (34%), Positives = 250/470 (53%), Gaps = 22/470 (4%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F +Y+  +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123
           + F +G+   W  IG   G   ++ L+  RLR++      A+TLPDY   R +D ++++R
Sbjct: 67  AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           I+SA +IL+F T Y  +   AG + F   F +S  T +         Y   GGF AV WT
Sbjct: 127 IISALVILLFFTIYCGSGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243
           D VQA  M+  LI+ P++ +V +GG   + ++I       +    G   + AI+  +G  
Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243

Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297
            W +GY GQPHI+ R+M+ +    +   RR    IS  W  + L GA   GF G A    
Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298

Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
               +G++  ++ ER+   +A      W+AG +++ I++AVMST   Q+LV SSAI  D+
Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQMLVCSSAITEDL 357

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y   L +   ++++V + R++V  VAL+A+  A      +  +V+ AW G    FGP++ 
Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLG 463
            S+ W R+T+   + GM  G ++ ++   K YGW       PGF FG+LG
Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSLG 465


>gb|AAA99290.1| (L01148) proline permease [Salmonella sp.]
           Length = 489
           
 Score =  284 bits (719), Expect = 2e-75
 Identities = 166/500 (33%), Positives = 258/500 (51%), Gaps = 41/500 (8%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F +Y+  +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123
           + F +G+   W  IG   G   ++ L+  RLR++      A+TLPDY   R +D ++++R
Sbjct: 67  AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           I+SA +IL+F T Y A+   AG + F   F +S  T +         Y   GGF AV WT
Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243
           D VQA  M+  LI+ P++ +V +GG   + ++I       +    G   + AI+  +G  
Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKG-LNFVAIISLMG-- 243

Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297
            W +GY GQPHI+ R+M+ +    +   RR    IS  W  + L GA   GF G A    
Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298

Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
               +G++  ++ ER+   +A      W+AG +++ I++AVMST   QLLV SSAI  D+
Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSAITEDL 357

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y   L +   ++++V + R++V  VAL+A+  A      +  +V  AW G    FGP++ 
Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVTYAWAGFGAAFGPVVL 417

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLGQWFNGVPVFF 473
            S+ W R+T+   + GM  G ++ ++   K YGW       PGF FG++           
Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSI----------- 464

Query: 474 INFFVTLFIIIIVSLLTKPP 493
                   +I++ SLL K P
Sbjct: 465 --------VIVLFSLLGKAP 476


>pir||G81202 sodium/proline symporter NMB0402 [imported] - Neisseria
           meningitidis (group B strain MD58, group A strain Z2491)
           >gi|7225624|gb|AAF40841.1| (AE002396) sodium/proline
           symporter [Neisseria meningitidis MC58]
           >gi|7380708|emb|CAB85299.1| (AL162758) sodium/proline
           symporter [Neisseria meningitidis Z2491]
           Length = 508
           
 Score =  280 bits (708), Expect = 3e-74
 Identities = 170/495 (34%), Positives = 254/495 (50%), Gaps = 23/495 (4%)

Query: 9   FLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFK 68
           F IYLV +  IG  A   T+  D Y +GGR +      +S  ASD SGWL++G PG+ + 
Sbjct: 8   FAIYLVAVLLIGLAAYFSTRNFDDYILGGRSLGPFVTAMSAGASDMSGWLLMGLPGAIYL 67

Query: 69  AGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFR-AITLPDYLEARLKDNTKLIRILSA 127
           +GL   W  IG L G   ++LL+  RLR++      A+TLPDY   R      L++++SA
Sbjct: 68  SGLNEAWIAIGLLVGAYFNWLLVAGRLRVHTEYANNALTLPDYFFHRFGAGGHLMKVVSA 127

Query: 128 AIILVFMTAYVAAQFAAGGKTFAQAFN-VSVTTGILITVIILTAYVITGGFFAVVWTDVV 186
            IIL F T Y A+   AG   F   F  ++    + +      AY   GGF AV WTD +
Sbjct: 128 LIILFFFTIYCASGIVAGATLFQSLFEGMTYNQAMWLGAGATIAYTFLGGFLAVSWTDTL 187

Query: 187 QAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWI 246
           QA  M+  LI+ P++  + +GG ++ +  I SV       +G       ++  I  A+W 
Sbjct: 188 QASLMIFALILTPVMVYLGLGGAEQMSAAIQSVAAGTGKEYGSLFAGTTVIGIISTAAWG 247

Query: 247 VGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFALVASGSI 303
           +GY GQPHI+ R+M+ E  + L   RR G+     W  + L GA   G+ G A   +   
Sbjct: 248 LGYFGQPHILARFMAAESAKSLVSARRIGM----TWMALCLAGAVAVGYFGIAYFGANPD 303

Query: 304 KVE----DPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKV 359
           KV     + ERI  A++      W+AG +++ I++AVMST   QLLV SSAI  D Y   
Sbjct: 304 KVSSMSGNHERIFIALSTLLFNPWIAGIILSAILAAVMSTLSCQLLVCSSAITEDFYKGF 363

Query: 360 LGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLW 419
           L +   + ++V + R++V A+A++++  A      +  +V+ AW G    FGPI+ LS+ 
Sbjct: 364 LRKNAQQSELVWVGRLMVLAIAVISILIASDPNSKVLGLVSYAWAGFGAAFGPIVILSVL 423

Query: 420 WKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNP-KAPGFFGTLGQWFNGVPVFFINFFV 478
           WKR+T    + GM  G ++ V+       W   P +A G  G L   +  VP     F V
Sbjct: 424 WKRITAYGALSGMVAGALTVVVWAE----WVKKPAQAAGESGLL-TMYEIVP----GFIV 474

Query: 479 TLFIIIIVSLLTKPP 493
            L + ++VSL  K P
Sbjct: 475 CLIVAVLVSLFNKEP 489


>gb|AAF25001.1|AF153207_2 (AF153207) proline permease [Pseudomonas putida]
           >gi|8132050|gb|AAF73192.1|AF151964_1 (AF151964) proline
           permease [Pseudomonas putida]
           Length = 492
           
 Score =  278 bits (703), Expect = 1e-73
 Identities = 169/502 (33%), Positives = 253/502 (49%), Gaps = 37/502 (7%)

Query: 9   FLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFK 68
           F+IY+  +  IG+ A + T     Y +GGR +  +   LS  ASD SGWL++G PG+ + 
Sbjct: 9   FVIYIAAMVLIGFAAYRATNNLSDYILGGRSLGSVVTALSAGASDMSGWLLMGLPGAIYF 68

Query: 69  AGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIRILSA 127
           AGL   W  IG   G   ++L +  RLR+       A+TLPDY  +R +DN+ L+RI+SA
Sbjct: 69  AGLSEAWIAIGLTVGAYLNWLFVAGRLRVQTEHNGDALTLPDYFSSRFEDNSGLLRIISA 128

Query: 128 AIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQ 187
            +ILVF T Y A+   AG + F   F +S  T +        AY   GGF AV WTD VQ
Sbjct: 129 IVILVFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIAYTFVGGFLAVSWTDTVQ 188

Query: 188 AMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIV 247
           A  M+  LI+ P++ L+  GG D+    I +V+        GAT     +  I    W +
Sbjct: 189 ASLMIFALILTPVIVLISTGGFDQTFAAIEAVNRRNFDMLKGAT----FIGIISLMGWGL 244

Query: 248 GYLGQPHIVTRYM---SVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVA----- 299
           GY   PHI+ R+M   SV    K RR    IS  W  + L G    GF G A  +     
Sbjct: 245 GYFRPPHILARFMAADSVNSIAKARR----ISMTWMILCLAGTCAVGFCGIAYFSAHPEL 300

Query: 300 SGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKV 359
           +G +  E+ +R+   +A      WVAG +++ I++AVM T   QLLV SSA+  + Y   
Sbjct: 301 AGPVS-ENHKRVFIELAKILFNPWVAGVLLSAILAAVMITLSCQLLVCSSALTENFYKAF 359

Query: 360 LGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLW 419
           L +   + ++V + R++V AVAL+A+  A      +  +VA AW G    FGP++ +S+ 
Sbjct: 360 LRKNASQVELVWVGRLMVLAVALIAIAMAANPENRVLGLVAYAWAGFGAAFGPVVLISVL 419

Query: 420 WKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVT 479
           WK +T+   + G+  G ++ ++ +               F TLG  +  +P     F   
Sbjct: 420 WKGMTRNGALAGIVVGALTVILWKN--------------FDTLG-LYEIIP----GFLFA 460

Query: 480 LFIIIIVSLLTKPPEDVVKLHE 501
              I++VS L  P + +VK  E
Sbjct: 461 SIAIVLVSKLGSPSQTMVKRFE 482


>pir||B69759 sodium/proline symporter ycgO - Bacillus subtilis
           >gi|1805394|dbj|BAA08956.1| (D50453) homologue of
           proline permease of E. coli [Bacillus subtilis]
           >gi|2632608|emb|CAB12116.1| (Z99105) similar to proline
           permease [Bacillus subtilis]
           Length = 449
           
 Score =  277 bits (702), Expect = 2e-73
 Identities = 159/452 (35%), Positives = 237/452 (52%), Gaps = 24/452 (5%)

Query: 47  LSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKF-RAI 105
           LS  A+D SGWL++G PG+ F  GL   W  IG   G  A++L + PRLR Y  K   +I
Sbjct: 8   LSAGAADMSGWLLMGLPGAMFSTGLSGAWIVIGLCLGAWANWLYVAPRLRTYTEKAGNSI 67

Query: 106 TLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITV 165
           T+P +LE R  D TKL+R+ S  +ILVF T YV++   +GG  F     +   TG+ I  
Sbjct: 68  TIPGFLENRFGDQTKLLRLFSGIVILVFFTFYVSSGMVSGGVLFNSILGMDYHTGLWIVT 127

Query: 166 IILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLH 225
            ++ AY + GGF AV WTD VQ + M   LI++PI+     GG       I SVDP+  +
Sbjct: 128 GVVVAYTLFGGFLAVSWTDFVQGIIMFAALILVPIVTFFHTGGAGDTVAEIRSVDPDMFN 187

Query: 226 PFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLW 285
            F G     +++  I   +W +GY GQPHI+ R+M++   ++++R      G W  +   
Sbjct: 188 IFKG----TSVLGIISLFAWGLGYFGQPHIIVRFMAITSVKEIKRARRIGMG-WMILSAV 242

Query: 286 GAFFAGFLGFALVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLL 345
           GA   G  G A      + ++DPE I   +        + GF+I+ I++A+MST  SQLL
Sbjct: 243 GAVLTGLGGIAYYHQRGMTLKDPETIFIQLGNILFHPIITGFLISAILAAIMSTISSQLL 302

Query: 346 VASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGG 405
           V SS++  D+Y  +  +    K++V + R+ V AV++VA+  A      I  +V+ AW G
Sbjct: 303 VTSSSLVEDLYKSMFRRSASDKELVFLGRLAVLAVSIVALVLAWEKNNTILGLVSYAWAG 362

Query: 406 LAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQW 465
               FGP++ LSL+WKR+TK   + GM  G  + +I       WA N     F       
Sbjct: 363 FGASFGPVVLLSLFWKRMTKWGALAGMIVGAATVII-------WA-NAGLSDFL------ 408

Query: 466 FNGVPVFFINFFVTLFIIIIVSLLTKPPEDVV 497
           +  +P     F  +L  +  VS+LT+ P   V
Sbjct: 409 YEMIP----GFAASLLSVFFVSILTQAPSQAV 436


>gb|AAG19342.1| (AE005029) proline permease; PutP [Halobacterium sp. NRC-1]
           Length = 522
           
 Score =  277 bits (700), Expect = 3e-73
 Identities = 162/470 (34%), Positives = 250/470 (52%), Gaps = 22/470 (4%)

Query: 33  YFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIG 92
           Y +GGR V  +    S++AS+ SGWL LG PG A+  G+ AF+ G+G +   LA +  + 
Sbjct: 7   YVIGGRDVGPVVTGFSERASEMSGWLTLGVPGDAYTTGIMAFYNGVGMIPADLAAWAGLA 66

Query: 93  PRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQA 152
            RLR Y+   RA+TLP +   RL D+T +++ +S+ +++VF  +YV AQ  A G      
Sbjct: 67  KRLRKYSEIVRAVTLPTFFATRLNDDTGVVKAVSSFVLIVFEGSYVGAQIVAAGTLLRVL 126

Query: 153 FNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRA 212
             V +  GI+   +I+  Y + GG+FAV W+D  Q   +L    I+PI+A     GL  A
Sbjct: 127 TGVDMWVGIVAGGVIVVGYTMLGGYFAVAWSDYFQGAIILAAFAILPIIAYA-TWGLPFA 185

Query: 213 TQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPG 272
                    +     GGATGWAA+   I YA+  +G  G PHI+ R+M ++  R +R   
Sbjct: 186 DLAAMDNGASLTSITGGATGWAALFGIISYAAVGLGIPGNPHIMVRFMGIDRVRNVRTAA 245

Query: 273 IFISGIWTTIVLWGAFFAGFLGFALVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGI 332
           + ++ ++  +   GA   G   +AL   G +  E+ +  +P + +  LP  VAG V+A  
Sbjct: 246 V-VAQLFMFVAYIGAALVGL--YALTQFGGL--ENTDNAMPLVTLELLPSAVAGVVLAAA 300

Query: 333 ISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGP 392
           ++A+MS+ADSQLLVA+SA+  D+YH  L ++  + Q+V  SR V  A+   ++ FA    
Sbjct: 301 LAAMMSSADSQLLVATSAVVEDVYHGFLNEQATEAQLVRYSRYVTLAIGFASIGFAYVAR 360

Query: 393 KV-IYQMVAT-AWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVILE--AKIYG 448
              IY++V   AWGGL    GP+L   LWW+RVT    +  M  G  + ++      I G
Sbjct: 361 NTPIYELVLNYAWGGLGAALGPLLIAVLWWRRVTAAGAVASMVTGTATMILWTQWPTILG 420

Query: 449 ----WAFNPKAPGFFGTLGQWFNGVPVFFINFFVTLFIIIIVSLLTKPPE 494
                +F+P   G     G         F  F V+  ++++VSLLT PP+
Sbjct: 421 PETVNSFHPAVSGMLTVYG--------LFPAFVVSAVVLVVVSLLTTPPD 462


>sp|P45174|PUTP_HAEIN SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE) >gi|1075316|pir||E64118
           sodium/proline symporter - Haemophilus influenzae
           (strain Rd KW20) >gi|1574814|gb|AAC22999.1| (U32814)
           sodium/proline symporter (proline permease) (putP)
           [Haemophilus influenzae Rd]
           Length = 504
           
 Score =  275 bits (697), Expect = 7e-73
 Identities = 159/505 (31%), Positives = 250/505 (49%), Gaps = 19/505 (3%)

Query: 6   LFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65
           L  F IY+  +  IG  A  YT     Y +GGR++      +S  ASD SGWL++G PG+
Sbjct: 8   LITFTIYIFGMLLIGVLAYYYTNNLSDYILGGRRLGSFVTAMSAGASDMSGWLLMGLPGA 67

Query: 66  AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIRI 124
            + +GL   W  IG   G   ++LL+  RLR+Y      A+TLP+Y   R   + KL+++
Sbjct: 68  VYLSGLVEGWIAIGLTIGAYFNWLLVAGRLRVYTELNNNALTLPEYFHNRFGSSHKLLKL 127

Query: 125 LSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTD 184
           +SA IILVF+T Y A+   AG K F   F+V  +T +        AY   GGF AV WTD
Sbjct: 128 VSATIILVFLTIYCASGVVAGAKLFQNIFSVEYSTALWYGAAATIAYTFIGGFLAVSWTD 187

Query: 185 VVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYAS 244
            +QA  M+  LI+ P+  L+      + + ++   +      F         +  +  A+
Sbjct: 188 TIQATLMIFALILTPVFVLLSFADTAQFSAVLEQAEAAVNKDFTDLFTSTTPLGLLSLAA 247

Query: 245 WIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLG----FALVAS 300
           W +GY GQPHI+ R+M+ +  + L +      G W  + L GA   G       FA  A 
Sbjct: 248 WGLGYFGQPHILARFMAADSVKSLIKARRISMG-WMVLCLAGAIGIGLFAIPYFFANPAI 306

Query: 301 GSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVL 360
                 +PE++   +A      W+AG +++ I++AVMST  +QLL++SS+I  D Y   +
Sbjct: 307 AGTVNREPEQVFIELAKLLFNPWIAGILLSAILAAVMSTLSAQLLISSSSITEDFYKGFI 366

Query: 361 GQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWW 420
                +K++V + RI+V  +A +A+W A      + ++V  AW G    FGP++  SL+W
Sbjct: 367 RPNASEKELVWLGRIMVLVIAALAIWIAQDENSKVLKLVEFAWAGFGSAFGPVVLFSLFW 426

Query: 421 KRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTL 480
           KR+T    + GM  G ++       ++ W     A         WF    +     F +L
Sbjct: 427 KRMTSSGAMAGMLVGAVT-------VFAWKEVVPAD------TDWFKVYEMIPGFAFASL 473

Query: 481 FIIIIVSLLTKPPEDVVKLHEELFK 505
            II+I  L  KP +D++   ++  K
Sbjct: 474 AIIVISLLSNKPEQDILNTFDKAEK 498


>emb|CAA70363.1| (Y09163) proline transport system [Corynebacterium glutamicum]
           Length = 524
           
 Score =  266 bits (673), Expect = 4e-70
 Identities = 163/533 (30%), Positives = 260/533 (48%), Gaps = 38/533 (7%)

Query: 2   NFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLG 61
           N   +   +IY++++  IG+W+ + T+  D Y + GR ++   A +S  ASD SGWL++G
Sbjct: 4   NTWFIIAIVIYMLVMVLIGYWSYRKTEKYDDYMLAGRGLNPFVAAMSAGASDMSGWLLMG 63

Query: 62  YPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTK 120
            PG+ F  G+   W  +G   G  A+++ + PRLR Y+     +ITLP + E RL+D ++
Sbjct: 64  LPGALFVTGMSELWIAVGLTIGAWANWMWVAPRLRSYSEISANSITLPSFFENRLRDKSR 123

Query: 121 LIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAV 180
            +RI++A II+VF T Y+++   AGG  +   F      G+ I   +   Y   GGF AV
Sbjct: 124 ALRIIAALIIIVFFTFYISSGMVAGGVYWESTFGGDYLLGMAIVAGVTVLYTFIGGFLAV 183

Query: 181 VWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHP----FGGATGWAAI 236
            +TD VQ   M  +LII+P++A      L     I +  + N   P     G  T ++ I
Sbjct: 184 SYTDAVQGTIMFFSLIIVPVMAYF---ALANPMDIWSFANSNDYGPHTDGIGNPTYFSMI 240

Query: 237 -----VFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAG 291
                   IG   W +GY GQPHIV R+M++  P + ++ G  I   W  I L GA F  
Sbjct: 241 SGISAAAIIGNLGWGLGYFGQPHIVVRFMALRTPAEAKQ-GRRIGISWMIICLIGATFTA 299

Query: 292 FLGFALVASG-SIKVEDP---ERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVA 347
            +     A      + D    E I   +A       +AG ++  +++A+MST  SQLLV 
Sbjct: 300 IISTVFFAQNPDANITDTRAYESIFLDLARMLFHPLIAGLILTAVLAAIMSTMSSQLLVT 359

Query: 348 SSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLA 407
           +S++  D+   V    L ++ ++ +SR  V  +A++A   AI     I  +V  AW G  
Sbjct: 360 ASSLIEDLLKVVKKDSLSERTLIMLSRATVIILAIIAAAMAINPSDSILGLVGFAWAGFG 419

Query: 408 VGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFN 467
             FGPI+  SL+WKR+     I GM  G I  +        W  +P +   +  +     
Sbjct: 420 SAFGPIILASLYWKRLNAAGAISGMITGAIVSI-------AWGMSPLSDTLYEIIP---- 468

Query: 468 GVPVFFINFFVTLFIIIIVSLLTKPPEDVVKLHEELFKKV--PIEKSEKIKTA 518
                   F +   ++++VSLLTK P + +    E  K +   +E +E +  A
Sbjct: 469 -------GFALATIVMVVVSLLTKEPSEEILNEFETAKDLAAAVESNEDVDFA 514


>pir||E75138 osmoregulated proline transporter PAB0609 - Pyrococcus abyssi
           (strain Orsay) >gi|5458333|emb|CAB49822.1| (AJ248285)
           OSMOREGULATED PROLINE TRANSPORTER [Pyrococcus abyssi]
           Length = 484
           
 Score =  255 bits (644), Expect = 1e-66
 Identities = 161/501 (32%), Positives = 254/501 (50%), Gaps = 39/501 (7%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           IL   + YL  L  +G +  +  K+   + + GR++    A LS++A+  S W +LG PG
Sbjct: 7   ILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRI 124
            AF AGL A W  IGC+ G +  + +   RLR  A K+ A+T  DY+  R  +  K IRI
Sbjct: 67  FAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRI 126

Query: 125 LSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTD 184
           L +A I  F   YV AQ+  GGK     F +    G+LIT +++  Y + GG  +V +TD
Sbjct: 127 LGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTD 186

Query: 185 VVQAMFMLLTLIIMPILALVEIGGLDR--ATQIIASVDPNKLH---PFGGATGWAAIVFA 239
            VQA+ M+LTLI+ PI+ ++ I       AT + A++    +      GG  G AAIVF 
Sbjct: 187 TVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFV 246

Query: 240 IGYASWIVGYL-GQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALV 298
           I   SW  GYL G P +  R+M+++D +  +       G WT I   GA   G++G A+ 
Sbjct: 247 IAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIG-WTIIAYIGALMIGWIGIAIF 305

Query: 299 ASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHK 358
               +K  DPE+++P++ +   P  +A   I G ++A++STADS L+++S+  + +I   
Sbjct: 306 GPNGLK--DPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENILKP 363

Query: 359 -VLGQELGKKQMVNISRIVVAAVALVAMWFAITGPK-VIYQMVATAWGGLAVGFGPILTL 416
            +   E   ++ + +SR+   ++ ++A+  A   P  +IY +V   W G+   F  I+ L
Sbjct: 364 YIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVIL 423

Query: 417 SLWWKRVTKEAGIVGMAYGLISEVI-----LEAKIYGWAFNPKAPGFFGTLGQWFNGVPV 471
           +L+WKR   +A    +  GL+  V      L+AK                       V V
Sbjct: 424 TLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAK-----------------------VSV 460

Query: 472 FFINFFVTLFIIIIVSLLTKP 492
             +NF VT  + II +   KP
Sbjct: 461 RLMNFIVTFIVAIIATYAIKP 481


>pir||C69115 sodium/proline symporter (proline permease) - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622992|gb|AAB86322.1| (AE000938) sodium/proline
           symporter (proline permease) [Methanobacterium
           thermoautotrophicum]
           Length = 526
           
 Score =  191 bits (481), Expect = 1e-47
 Identities = 134/521 (25%), Positives = 239/521 (45%), Gaps = 50/521 (9%)

Query: 10  LIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKA 69
           LIY +++ Y+G+ A + T+T + Y V GR+ H     +S  A+  S   ++G+ G A   
Sbjct: 11  LIYFLLVGYVGYVAWRRTETSEDYMVAGRRTHPYIMAMSYGATFISTAAIVGFGGMAGVF 70

Query: 70  GLGAFW-AGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAA 128
           G+G  W   +  L G    ++  G R         A+T P++L  R   N++ ++    A
Sbjct: 71  GMGILWLVFLNILVGIFIAFVFFGKRTMKMGHNMSALTFPEFLGRRF--NSRFLQYFGGA 128

Query: 129 IILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQA 188
           II + M  Y +       +       +  +  +++  +I+  YV+ GG   V++TD +Q 
Sbjct: 129 IIFLGMPLYASVVLIGAARFIETTLGLDFSIALILMAVIVAVYVVLGGIRGVMYTDALQG 188

Query: 189 MFMLLTLIIMPILALVEIGGLDRATQIIASVD---PNKLHPFGGATGW------------ 233
             M L +I + +     +GG+  A Q + ++    P K     GATGW            
Sbjct: 189 TIMFLGMIFLVVSTYYLLGGVVDAHQALTNISHLIPAKARAI-GATGWTSMPLYGSPYWW 247

Query: 234 ---AAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFA 290
              + I+  +G     VG L QP ++ R+M+V+  R+L R G+ I  ++  ++ W A+  
Sbjct: 248 TLLSTIILGVG-----VGVLAQPQLIVRFMTVKSNRELNR-GVLIGALFIFVMTWSAYVV 301

Query: 291 GFLG--FALVASGSIKVE----DPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQL 344
           G L   +     G I V+    + ++I+P      +P W +   +  ++SA MST  +Q 
Sbjct: 302 GALSNVYFFRKMGMIAVQAAGGNADKIIPFFIKSAMPEWFSYIFMLTLLSAAMSTLSAQF 361

Query: 345 LVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWG 404
            V  +AI RD+Y  V  ++  +  ++    I++A +  V + + + G  ++ Q  A  +G
Sbjct: 362 HVQGTAIGRDVYETVRRRKGDRSVLITRGGIIIAVLIAVVLGYLLPG-SIVAQGTALFFG 420

Query: 405 GLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQ 464
             A  F  +   +++WKR T++  I GM  G I  V L   ++ +    +A G    L  
Sbjct: 421 ICAASFLSVYVAAIFWKRATRQGAIAGMVSGAI--VSLFWLLFEYKKTAEALGIAKAL-- 476

Query: 465 WFNG----------VPVFFINFFVTLFIIIIVSLLTKPPED 495
            F G          V    +   V+   ++ VSLLT+PP D
Sbjct: 477 -FGGPVIASMPWPVVDPILVGVPVSAIFMVAVSLLTEPPSD 516


>pir||D65118 pantothenate permease [validated] - Escherichia coli
           >gi|606198|gb|AAA58061.1| (U18997) pantothenate permease
           [Escherichia coli] >gi|1789656|gb|AAC76290.1| (AE000404)
           sodium/pantothenate symporter [Escherichia coli K12]
           Length = 485
           
 Score =  184 bits (462), Expect = 2e-45
 Identities = 133/473 (28%), Positives = 234/473 (49%), Gaps = 24/473 (5%)

Query: 1   MNFGILFGFLIYLVILAYIGWWANKYTKTE---DQYFVGGRKVHVLAATLSDKASDFSGW 57
           M   ++   + YLV++  I  +A +   T    ++YF+G R +  +   ++  A+  S  
Sbjct: 3   MQLEVILPLVAYLVVVFGISVYAMRKRSTGTFLNEYFLGSRSMGGIVLAMTLTATYISAS 62

Query: 58  LMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKD 117
             +G PG+A+K GLG     +  L        ++G +  I A ++ A+TL D L AR + 
Sbjct: 63  SFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILARRYNAVTLNDMLFARYQ- 121

Query: 118 NTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGF 177
            ++L+  L++  +LV     +  QF  G +    A  +   TG+LI  I +  Y   GGF
Sbjct: 122 -SRLLVWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYETGLLIFGISIALYTAFGGF 180

Query: 178 FAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIV 237
            A V  D +Q + ML+  +++ I  +   GGL  A Q + ++DP  + P  GA    +  
Sbjct: 181 RASVLNDTMQGLVMLIGTVVLLIGVVHAAGGLSNAVQTLQTIDPQLVTP-QGADDILSPA 239

Query: 238 FAIGYASWIV---GYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLG 294
           F   +  W++   G +G PH   R +S +D + + R GI I  I   I+++G   AG LG
Sbjct: 240 FMTSF--WVLVCFGVIGLPHTAVRCISYKDSKAVHR-GIIIGTIVVAILMFGMHLAGALG 296

Query: 295 FALVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARD 354
            A++   ++    P+ ++P + +  LP + AG  +A  ++A+MST ++QLL +S+ I +D
Sbjct: 297 RAVIPDLTV----PDLVIPTLMVKVLPPFAAGIFLAAPMAAIMSTINAQLLQSSATIIKD 352

Query: 355 IYHKV----LGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGF 410
           +Y  +    +  E   K+M  +  +V+ A+ L+A W     P++I  +   A+GGL   F
Sbjct: 353 LYLNIRPDQMQNETRLKRMSAVITLVLGALLLLAAW---KPPEMIIWLNLLAFGGLEAVF 409

Query: 411 GPILTLSLWWKRVTKEAGIVGMAY-GLISEVILEAKIYGWAFNPKAPGFFGTL 462
              L L L+W+R   +  +  M   G++  V+    I    F+P  P    +L
Sbjct: 410 LWPLVLGLYWERANAKGALSAMIVGGVLYAVLATLNIQYLGFHPIVPSLLLSL 462


>sp|P16256|PANF_ECOLI SODIUM/PANTOTHENATE SYMPORTER (PANTOTHENATE PERMEASE)
           Length = 483
           
 Score =  184 bits (462), Expect = 2e-45
 Identities = 133/473 (28%), Positives = 234/473 (49%), Gaps = 24/473 (5%)

Query: 1   MNFGILFGFLIYLVILAYIGWWANKYTKTE---DQYFVGGRKVHVLAATLSDKASDFSGW 57
           M   ++   + YLV++  I  +A +   T    ++YF+G R +  +   ++  A+  S  
Sbjct: 1   MQLEVILPLVAYLVVVFGISVYAMRKRSTGTFLNEYFLGSRSMGGIVLAMTLTATYISAS 60

Query: 58  LMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKD 117
             +G PG+A+K GLG     +  L        ++G +  I A ++ A+TL D L AR + 
Sbjct: 61  SFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILARRYNAVTLNDMLFARYQ- 119

Query: 118 NTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGF 177
            ++L+  L++  +LV     +  QF  G +    A  +   TG+LI  I +  Y   GGF
Sbjct: 120 -SRLLVWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYETGLLIFGISIALYTAFGGF 178

Query: 178 FAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIV 237
            A V  D +Q + ML+  +++ I  +   GGL  A Q + ++DP  + P  GA    +  
Sbjct: 179 RASVLNDTMQGLVMLIGTVVLLIGVVHAAGGLSNAVQTLQTIDPQLVTP-QGADDILSPA 237

Query: 238 FAIGYASWIV---GYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLG 294
           F   +  W++   G +G PH   R +S +D + + R GI I  I   I+++G   AG LG
Sbjct: 238 FMTSF--WVLVCFGVIGLPHTAVRCISYKDSKAVHR-GIIIGTIVVAILMFGMHLAGALG 294

Query: 295 FALVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARD 354
            A++   ++    P+ ++P + +  LP + AG  +A  ++A+MST ++QLL +S+ I +D
Sbjct: 295 RAVIPDLTV----PDLVIPTLMVKVLPPFAAGIFLAAPMAAIMSTINAQLLQSSATIIKD 350

Query: 355 IYHKV----LGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGF 410
           +Y  +    +  E   K+M  +  +V+ A+ L+A W     P++I  +   A+GGL   F
Sbjct: 351 LYLNIRPDQMQNETRLKRMSAVITLVLGALLLLAAW---KPPEMIIWLNLLAFGGLEAVF 407

Query: 411 GPILTLSLWWKRVTKEAGIVGMAY-GLISEVILEAKIYGWAFNPKAPGFFGTL 462
              L L L+W+R   +  +  M   G++  V+    I    F+P  P    +L
Sbjct: 408 LWPLVLGLYWERANAKGALSAMIVGGVLYAVLATLNIQYLGFHPIVPSLLLSL 460


>sp|P44963|PANF_HAEIN SODIUM/PANTOTHENATE SYMPORTER (PANTOTHENATE PERMEASE)
           >gi|1075105|pir||H64105 pantothenate transport protein -
           Haemophilus influenzae  (strain Rd KW20)
           >gi|1574003|gb|AAC22634.1| (U32778) sodium/pantothenate
           symporter (panF) [Haemophilus influenzae Rd]
           Length = 484
           
 Score =  180 bits (452), Expect = 4e-44
 Identities = 130/464 (28%), Positives = 223/464 (48%), Gaps = 47/464 (10%)

Query: 1   MNFGILFGFLIYLV------ILAYIGWWANKYTKTE--DQYFVGGRKVHVLAATLSDKAS 52
           MN GI+   +IYL       I AY+     K TK +   +Y+VG R +      ++  ++
Sbjct: 1   MNLGIILPLIIYLTFVFGAAIFAYV-----KRTKGDFLTEYYVGNRSMTGFVLAMTTAST 55

Query: 53  DFSGWLMLGYPGSAFKAGLG----------AFWAGIGCLFGTLADYLLIGPRLRIYAGKF 102
             S    +G PG+A+K GLG            W  +G L          G +  + + + 
Sbjct: 56  YASASSFVGGPGAAYKYGLGWVLLAMIQVPVVWLALGAL----------GKKFALLSRET 105

Query: 103 RAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGIL 162
            A+T+ D    R K N  L+ + S A++L F  A +  QF  G +       +S T  +L
Sbjct: 106 NALTINDLFFYRYK-NKYLVWLSSLALLLAFFAA-MTVQFIGGARLLETTIGISYTQALL 163

Query: 163 ITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPN 222
           +  + +  Y   GGF AVV TD +Q   M+   II+ I  +  +GG++ A   +  +DP+
Sbjct: 164 LFALTVGIYTFIGGFRAVVLTDTIQGTVMIFGTIILLIGTIYALGGVESAVNKLTEIDPD 223

Query: 223 KLHPFGGATGWAAIVFAIGYASWIV---GYLGQPHIVTRYMSVEDPRKLRRPGIFISGIW 279
            + P+ G  G     F   +  WI+   G +G PH   R M+ +D + L R G+ I  I 
Sbjct: 224 LVTPY-GPNGMLDFQFMASF--WILVCFGVVGLPHTAVRCMAFKDSKALHR-GMLIGTIV 279

Query: 280 TTIVLWGAFFAGFLGFALVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMST 339
            +I++ G   AG LG A++ + ++     ++++P + I  LP  VAG  +A  +SA+MST
Sbjct: 280 LSIIMLGMHLAGALGRAVIPNLTVS----DQVIPTLMIKVLPPIVAGIFLAAPMSAIMST 335

Query: 340 ADSQLLVASSAIARDIYHKVLGQEL-GKKQMVNISRIVVAAVALVAMWFAITGPKVIYQM 398
            D+QL+ +SS   +D+Y     +    +K++   S I+   +  + ++ A+  P +I  +
Sbjct: 336 IDAQLIQSSSIFVKDLYLSAKPEAAKNEKKVSYFSSIITLILTALLIFAALNPPDMIIWL 395

Query: 399 VATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVIL 442
              A+GGL   F  ++ L ++W +      +  M  GL S ++L
Sbjct: 396 NLFAFGGLEAAFLWVIVLGIYWDKANAYGALSSMIIGLGSYILL 439


>gb|AAF45263.1| (AF230602) proline permease [Escherichia coli]
           >gi|7288753|gb|AAF45265.1| (AF230604) proline permease
           [Escherichia coli] >gi|7288757|gb|AAF45267.1| (AF230606)
           proline permease [Escherichia coli]
           >gi|7288765|gb|AAF45271.1| (AF230610) proline permease
           [Escherichia coli] >gi|7288769|gb|AAF45273.1| (AF230612)
           proline permease [Escherichia coli]
           >gi|7288771|gb|AAF45274.1| (AF230613) proline permease
           [Escherichia coli] >gi|7288773|gb|AAF45275.1| (AF230614)
           proline permease [Escherichia coli]
           >gi|7288775|gb|AAF45276.1| (AF230615) proline permease
           [Escherichia coli] >gi|7288777|gb|AAF45277.1| (AF230616)
           proline permease [Escherichia coli]
           >gi|7288779|gb|AAF45278.1| (AF230617) proline permease
           [Escherichia coli] >gi|7288781|gb|AAF45279.1| (AF230618)
           proline permease [Escherichia coli]
           >gi|7288785|gb|AAF45281.1| (AF230620) proline permease
           [Escherichia coli] >gi|7288787|gb|AAF45282.1| (AF230621)
           proline permease [Escherichia coli]
           >gi|7288791|gb|AAF45284.1| (AF230623) proline permease
           [Escherichia coli] >gi|7288797|gb|AAF45287.1| (AF230626)
           proline permease [Escherichia coli]
           >gi|7288799|gb|AAF45288.1| (AF230627) proline permease
           [Escherichia coli] >gi|7288801|gb|AAF45289.1| (AF230628)
           proline permease [Escherichia coli]
           >gi|7288803|gb|AAF45290.1| (AF230629) proline permease
           [Escherichia coli] >gi|7288805|gb|AAF45291.1| (AF230630)
           proline permease [Escherichia coli]
           >gi|7288807|gb|AAF45292.1| (AF230631) proline permease
           [Escherichia coli] >gi|7288809|gb|AAF45293.1| (AF230632)
           proline permease [Escherichia coli]
           >gi|7288811|gb|AAF45294.1| (AF230633) proline permease
           [Escherichia coli] >gi|7288813|gb|AAF45295.1| (AF230634)
           proline permease [Escherichia coli]
           >gi|7288815|gb|AAF45296.1| (AF230635) proline permease
           [Escherichia coli]
           Length = 232
           
 Score =  171 bits (428), Expect = 2e-41
 Identities = 84/234 (35%), Positives = 128/234 (53%), Gaps = 5/234 (2%)

Query: 31  DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLL 90
           D Y +GGR +      LS  ASD SGWL++G PG+ F +G+   W  IG   G   ++ L
Sbjct: 2   DDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKL 61

Query: 91  IGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTF 149
           +  RLR++      A+TLPDY   R +D ++++RI+SA +IL+F T Y A+   AG + F
Sbjct: 62  VAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLF 121

Query: 150 AQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGL 209
              F +S  T +         Y   GGF AV WTD VQA  M+  LI+ P++ ++ +GG 
Sbjct: 122 ESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGF 181

Query: 210 DRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVE 263
             + ++I       +    G   + AI+  +G   W +GY GQPHI+ R+M+ +
Sbjct: 182 GDSLEVIKQKSIENVDMLKG-LNFVAIISLMG---WGLGYFGQPHILARFMAAD 231


>gb|AAF45280.1| (AF230619) proline permease [Escherichia coli]
           Length = 232
           
 Score =  171 bits (428), Expect = 2e-41
 Identities = 84/234 (35%), Positives = 128/234 (53%), Gaps = 5/234 (2%)

Query: 31  DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLL 90
           D Y +GGR +      LS  ASD SGWL++G PG+ F +G+   W  IG   G   ++ L
Sbjct: 2   DDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKL 61

Query: 91  IGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTF 149
           +  RLR++      A+TLPDY   R +D ++++RI+SA +IL+F T Y A+   AG + F
Sbjct: 62  VAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLF 121

Query: 150 AQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGL 209
              F +S  T +         Y   GGF AV WTD VQA  M+  LI+ P++ ++ +GG 
Sbjct: 122 ESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGF 181

Query: 210 DRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVE 263
             + ++I       +    G   + AI+  +G   W +GY GQPHI+ R+M+ +
Sbjct: 182 GDSLEVIKQKSIENVDMLKG-LNFVAIISLMG---WGLGYFGQPHILARFMAAD 231


>gb|AAF45283.1| (AF230622) proline permease [Escherichia coli]
           Length = 232
           
 Score =  171 bits (428), Expect = 2e-41
 Identities = 84/234 (35%), Positives = 128/234 (53%), Gaps = 5/234 (2%)

Query: 31  DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLL 90
           D Y +GGR +      LS  ASD SGWL++G PG+ F +G+   W  IG   G   ++ L
Sbjct: 2   DDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKL 61

Query: 91  IGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTF 149
           +  RLR++      A+TLPDY   R +D ++++RI+SA +IL+F T Y A+   AG + F
Sbjct: 62  VAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLF 121

Query: 150 AQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGL 209
              F +S  T +         Y   GGF AV WTD VQA  M+  LI+ P++ ++ +GG 
Sbjct: 122 ESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGF 181

Query: 210 DRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVE 263
             + ++I       +    G   + AI+  +G   W +GY GQPHI+ R+M+ +
Sbjct: 182 GDSLEVIKQKSIENVDMLKG-LNFVAIISLMG---WGLGYFGQPHILARFMAAD 231


>gb|AAF45285.1| (AF230624) proline permease [Escherichia coli]
           Length = 232
           
 Score =  171 bits (428), Expect = 2e-41
 Identities = 84/234 (35%), Positives = 128/234 (53%), Gaps = 5/234 (2%)

Query: 31  DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLL 90
           D Y +GGR +      LS  ASD SGWL++G PG+ F +G+   W  IG   G   ++ L
Sbjct: 2   DDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKL 61

Query: 91  IGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTF 149
           +  RLR++      A+TLPDY   R +D ++++RI+SA +IL+F T Y A+   AG + F
Sbjct: 62  VAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLF 121

Query: 150 AQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGL 209
              F +S  T +         Y   GGF AV WTD VQA  M+  LI+ P++ ++ +GG 
Sbjct: 122 ESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGF 181

Query: 210 DRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVE 263
             + ++I       +    G   + AI+  +G   W +GY GQPHI+ R+M+ +
Sbjct: 182 GDSLEVIKQKSIENVDMLKG-LNFVAIISLMG---WGMGYFGQPHILARFMAAD 231


>gb|AAF45264.1| (AF230603) proline permease [Escherichia coli]
           >gi|7288755|gb|AAF45266.1| (AF230605) proline permease
           [Escherichia coli] >gi|7288759|gb|AAF45268.1| (AF230607)
           proline permease [Escherichia coli]
           >gi|7288761|gb|AAF45269.1| (AF230608) proline permease
           [Escherichia coli] >gi|7288763|gb|AAF45270.1| (AF230609)
           proline permease [Escherichia coli]
           >gi|7288767|gb|AAF45272.1| (AF230611) proline permease
           [Escherichia coli]
           Length = 232
           
 Score =  170 bits (426), Expect = 4e-41
 Identities = 84/232 (36%), Positives = 127/232 (54%), Gaps = 5/232 (2%)

Query: 31  DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLL 90
           D Y +GGR +      LS  ASD SGWL++G PG+ F +G+   W  IG   G   ++ L
Sbjct: 2   DDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKL 61

Query: 91  IGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTF 149
           +  RLR++      A+TLPDY   R +D ++++RI+SA +IL+F T Y A+   AG + F
Sbjct: 62  VAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLF 121

Query: 150 AQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGL 209
              F +S  T +         Y   GGF AV WTD VQA  M+  LI+ P++ ++ +GG 
Sbjct: 122 ESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGF 181

Query: 210 DRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMS 261
             + ++I       +    G   + AI+  +G   W +GY GQPHI+ R+M+
Sbjct: 182 GDSLEVIKQKSIENVDMLKG-LNFVAIISLMG---WGLGYFGQPHILARFMA 229


>gb|AAF45286.1| (AF230625) proline permease [Escherichia coli]
           Length = 232
           
 Score =  168 bits (422), Expect = 1e-40
 Identities = 83/234 (35%), Positives = 128/234 (54%), Gaps = 5/234 (2%)

Query: 31  DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLL 90
           D Y +GGR +      LS  ASD SGWL++G PG+ F +G+   W  IG   G   ++ L
Sbjct: 2   DDYILGGRSLGPFVTALSVGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKL 61

Query: 91  IGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTF 149
           +  RLR++      A+TLP+Y   R +D ++++RI+SA +IL+F T Y A+   AG + F
Sbjct: 62  VAGRLRVHTEYNNNALTLPNYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLF 121

Query: 150 AQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGL 209
              F +S  T +         Y   GGF AV WTD VQA  M+  LI+ P++ ++ +GG 
Sbjct: 122 ESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGF 181

Query: 210 DRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVE 263
             + ++I       +    G   + AI+  +G   W +GY GQPHI+ R+M+ +
Sbjct: 182 GDSLEVIKQKSIENVDMLKG-LNFVAIISLMG---WGLGYFGQPHILARFMAAD 231


>gi|11497636 proline permease (putP-1) [Archaeoglobus fulgidus]
           >gi|7442766|pir||G69251 proline permease (putP-1)
           homolog - Archaeoglobus fulgidus
           >gi|2650635|gb|AAB91210.1| (AE001105) proline permease
           (putP-1) [Archaeoglobus fulgidus]
           Length = 491
           
 Score =  163 bits (409), Expect = 4e-39
 Identities = 129/490 (26%), Positives = 217/490 (43%), Gaps = 34/490 (6%)

Query: 10  LIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDF-SGWLMLGYPGSAFK 68
           L Y V+   +G++A +  KT + Y+ G RK+  +  T     S   S +  +G PG  + 
Sbjct: 11  LAYFVVTLALGFFAARKIKTAEHYY-GARKLFGMFVTAVAVFSGIASAFTFIGGPGLVYP 69

Query: 69  AGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAA 128
            G    W     +      + L+G R+++        TLPD   AR K +   +R L+A 
Sbjct: 70  MGGTVNWVIWTPVISMPLIWYLLGKRIKLITEARPVATLPDLTAARFKSDA--VRFLTAV 127

Query: 129 IILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQA 188
            ++  +  Y+A      G          +   I I   I+  Y   GG  A + TD  Q 
Sbjct: 128 ALIFGIITYLAGNVMGAGLVLTDMLGTPLELSIAIVFGIIMLYTAFGGMVASILTDFFQG 187

Query: 189 MFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASW--- 245
           + M++  II  +  L+  GG++     IA  +P  + P G    W      +G   W   
Sbjct: 188 LVMMVAAIIFVVFILIMTGGVENLFATIAESNPRHIDPIGVGPIW------LGIMGWWWA 241

Query: 246 -IVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWT-TIVLWGAFFAGFLGFALVASGSI 303
             +G   QPH VT++ +++D R L+   +  +  WT   ++W  FF G+    +V  G  
Sbjct: 242 LNIGSSVQPHAVTKFFALKDYRDLKWGALVTTIAWTLACLMW--FFGGYASVWVVIKG-- 297

Query: 304 KVEDPERIVPAM--AIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLG 361
             E P R   A+   I  +P  +   + AG+++A+MST    + + ++A+ RDI    +G
Sbjct: 298 LAEAPARSDQAIFGVIAQMPVVLKAVIYAGVLAAIMSTVSGFISMGTAAVVRDI-PTAIG 356

Query: 362 QELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWK 421
           + L ++  +   R+V   + +VA  F   G  V+  +V    G  A    P+L + L WK
Sbjct: 357 KSLSQRGQILWGRVVTVILTVVAALFGYYGGYVVGILVTLGLGYFASMLFPLLVIGLNWK 416

Query: 422 RVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTLF 481
           R TKEA I+  A  L   + L   +Y    +   P           G+P + + F V + 
Sbjct: 417 RATKEAAIITTA--LTVAMNLGFLVYEKVLSMSLP----------YGLPGYGVTFAVGII 464

Query: 482 IIIIVSLLTK 491
            +++VSL+TK
Sbjct: 465 TMVLVSLITK 474


>pir||JU0296 pantothenate permease - Escherichia coli >gi|147067|gb|AAA24276.1|
           (M30953) pantothenate permease (panF) [Escherichia coli]
           Length = 482
           
 Score =  153 bits (384), Expect = 3e-36
 Identities = 127/476 (26%), Positives = 222/476 (45%), Gaps = 31/476 (6%)

Query: 1   MNFGILFGFLIYLVILAYIGWWANKYTKTE---DQYFVGGRKVHVLAATLSDKASDFSGW 57
           M   ++   + YLV++  I  +A +   T    ++YF+G R +  +   ++  A+  S  
Sbjct: 1   MQLEVILPLVAYLVVVFGISVYAMRKRSTGTFLNEYFLGSRSMGGIVLAMTLTATYISAS 60

Query: 58  LMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKD 117
             +G PG+A+K GLG     +  L        ++G +  I A ++ A+TL D L AR + 
Sbjct: 61  SFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILARRYNAVTLNDMLFARYQ- 119

Query: 118 NTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGF 177
            ++L+  L++  +LV     +  QF  G +    A  +   TG+LI  I +  Y   GGF
Sbjct: 120 -SRLLVWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYETGLLIFGISIALYTAFGGF 178

Query: 178 FAVVWTDVVQAM---FMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWA 234
                    +A    +           A    GGL  A Q + ++DP  + P  GA    
Sbjct: 179 APAAERHHARACDADWHRCAAYWRSTCA----GGLSNAVQTLQTIDPQLVTP-QGADDIL 233

Query: 235 AIVFAIGYASWIV---GYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAG 291
           +  F   +  W++   G +G  H   R +S +D + + R GI I  I   I+++G   AG
Sbjct: 234 SPAFMTSF--WVLVCFGVIGLAHTAVRCISYKDSKAVHR-GIIIGTIVVAILMFGMHLAG 290

Query: 292 FLGFALVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAI 351
            LG A++    +    P+ ++P + +  LP + AG  +A  ++A+MST ++QLL +S+ I
Sbjct: 291 ALGRAVIPDLHV----PDLVIPTLMVKVLPPFAAGIFLAAPMAAIMSTINAQLLQSSATI 346

Query: 352 ARDIYHKV----LGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLA 407
            +D+Y  +    +  E   K+M  +  +V+ A+ L+A W     P++I  +   A+GGL 
Sbjct: 347 IKDLYLNIRPDQMQNETRLKRMSAVITLVLGALLLLAAW---KPPEMIIWLNLLAFGGLE 403

Query: 408 VGFGPILTLSLWWKRVTKEAGIVGMAY-GLISEVILEAKIYGWAFNPKAPGFFGTL 462
             F   L L L+W+R   +  +  M   G++  V+    I    F+P  P    +L
Sbjct: 404 AVFLWPLVLGLYWERANAKGALSAMIVGGVLYAVLATLNIQYLGFHPIVPSLLLSL 459


>pir||E70201 pantothenate permease (panF) homolog - Lyme disease spirochete
           >gi|2688763|gb|AAC67168.1| (AE001180) pantothenate
           permease (panF) [Borrelia burgdorferi]
           Length = 444
           
 Score =  142 bits (354), Expect = 1e-32
 Identities = 113/438 (25%), Positives = 209/438 (46%), Gaps = 26/438 (5%)

Query: 31  DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLL 90
           ++YF+  R ++ +   L   +S  S    +  P + +K GL         +  TL  +++
Sbjct: 4   NKYFLANRNINFIVMALLFSSSYISASSFISGPSAVYKYGLSFILLATIQIPTTLIVFII 63

Query: 91  IGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTFA 150
           +G RL   + K  AI + DY+  R + +   + ++S  +++ F    ++AQ   G K   
Sbjct: 64  VGQRLNRESKKINAINIIDYIRHRYESD--FLALMSGFVLIFFSMFLISAQLIGGAKLIE 121

Query: 151 QAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLD 210
             + +    G+     ++  YV  GGF AV +TD++Q   ML++ +I+    L   GG++
Sbjct: 122 VFWGIDYVVGLTFFAFLVFIYVFFGGFKAVAYTDLIQGFLMLVSSVILFSKMLDLGGGIN 181

Query: 211 RATQ-IIASVDPNKLHPFGGATGWAAIVFAIGYASWI---VGYLGQPHIVTRYMSVEDPR 266
              +   +S+D + L P         I+     + WI   +G LGQP I+  +++ +D  
Sbjct: 182 NLFKTATSSLDKSLLLPSNADLKPQYII-----SFWILIGIGILGQPQIINNFIAFKDEN 236

Query: 267 KLRRPGIFISGIWTTIVLWGAFFAGFLG-FALVASGSIKVEDPERIVPAMAIHFLPGWVA 325
            ++    F   I T I+ +       +G FA++    +   D  ++V  +A+  L  +  
Sbjct: 237 AIK----FSLPISTFIISFLIVLMHLIGFFAIILFPDLSPND--KVVLNVALKVLNPFSC 290

Query: 326 GFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAA---VAL 382
                G++SA+MST DS LL+ +S + + I+  +  ++L  K+ V I RI++ +     L
Sbjct: 291 FMFFIGLLSAIMSTVDSNLLLITSVLIKSIF--IYKEDL--KEDVKIGRIIMISNIFFIL 346

Query: 383 VAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEV-I 441
           + + F++  P  ++ +   A+G L V F PI+   L+   V+K A    M  GLI  + I
Sbjct: 347 IILIFSLFPPNFLFFINIFAFGALEVSFFPIIVFGLYLNFVSKIAAFASMFLGLIFYLSI 406

Query: 442 LEAKIYGWAFNPKAPGFF 459
           L   +  W F+P  P FF
Sbjct: 407 LFFGLNIWFFHPVFPSFF 424


>dbj|BAB07462.1| (AP001519) Na+/solute symporter (Ssf family) [Bacillus halodurans]
           Length = 554
           
 Score =  141 bits (353), Expect = 1e-32
 Identities = 128/499 (25%), Positives = 215/499 (42%), Gaps = 89/499 (17%)

Query: 58  LMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKD 117
           ++LGY G A+  G    W G G LF T     L  P+LR Y G++   T+P+++  R   
Sbjct: 68  MILGYDGLAYIMG----WTG-GYLFLTF----LFAPQLRKY-GRY---TVPEFIGDRYGS 114

Query: 118 NTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGF 177
           NT   R+++A   ++    Y+  Q +  G    +  N+    G +I V+++  Y   GG 
Sbjct: 115 NTA--RLIAAIATIIISFTYIIGQLSGSGVVIGRILNIPAMYGTMIGVVVIAIYATLGGM 172

Query: 178 FAVVWTDVVQAMFMLLTLIIMPILALVEIGG--------------LDRATQIIASVDPNK 223
             + WT V Q + +++  II  +   +++ G              LD   Q +       
Sbjct: 173 KGITWTQVAQYIILIVAYIIPIVFMSLQLSGNPFPWLTYGNFISQLDGLDQELGL--SQI 230

Query: 224 LHPF--GGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPG----IFISG 277
           L PF     + + A++F +     +VG    PH++ R+ +V   +  R  G    IFI+ 
Sbjct: 231 LQPFMESDKSQFIALMFTL-----MVGTAALPHVIVRFYTVTTMKAARWSGAWALIFIAL 285

Query: 278 IWTTIVLWGAFFAGFL-------------------------------GFALVASGSIKVE 306
           ++ +   + AF    L                               G  ++    +++ 
Sbjct: 286 LYLSAPAYAAFSRFILMTQVANQPIDQLPAWTEAWINTGLLEMADANGDGILQWEELRIS 345

Query: 307 DPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGK 366
           +   ++    I  L  +V G V AG ++A +STA   L+  SS+ A DIY++++  +   
Sbjct: 346 NDIVVMATPEIANLGMFVIGLVAAGAMAAALSTAGGLLITISSSFAHDIYYRLMNPKASD 405

Query: 367 KQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTKE 426
           ++ +   RI +    +VA   A+  P VI Q+VA A+G     F P+L L +WWKR   +
Sbjct: 406 QKRLLAGRIAIVLATIVAGVVALDPPGVITQIVAWAFGLAGGAFFPVLLLGVWWKRANAK 465

Query: 427 AGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFG--TLGQWFNGVPVFFINFFVTLFIII 484
             I GM  GL   +     +Y +         FG    G    GVP       V LF+ I
Sbjct: 466 GAIAGMLSGLAVTL-----VYIFLARTGTFTLFGIQDTGAGLIGVP-------VNLFVTI 513

Query: 485 IVSLLTKPPEDVVKLHEEL 503
           +VSL+T  P    KL +E+
Sbjct: 514 VVSLMTAAPSQ--KLQDEV 530


>gi|11498674 pantothenate permease (panF-1) [Archaeoglobus fulgidus]
           >gi|7442768|pir||E69383 pantothenate permease (panF-1)
           homolog - Archaeoglobus fulgidus
           >gi|2649519|gb|AAB90171.1| (AE001029) pantothenate
           permease (panF-1) [Archaeoglobus fulgidus]
           Length = 491
           
 Score =  139 bits (347), Expect = 7e-32
 Identities = 112/468 (23%), Positives = 218/468 (45%), Gaps = 31/468 (6%)

Query: 12  YLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGL 71
           YL ++  IG +  + T+    Y++ G+K+  L  + S  A+ FS    LG  G+ F  G 
Sbjct: 10  YLAVVLLIGIYEYRKTRGLLDYYLAGKKLGTLVVSFSFFATYFSTAAFLGGGGTGFLLGF 69

Query: 72  --GAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAAI 129
              AF      LF  LA +++I P ++  A ++ A+T+P+    R        +I++A +
Sbjct: 70  QWSAFLTFFHVLFAILA-WMVIAPPMKRIADEYGALTIPELFRKRAG---VFSQIVAAVV 125

Query: 130 ILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAM 189
           I+ F   Y+ + +   G       ++  TTG++IT +I+  Y   GGF AVV TD++Q +
Sbjct: 126 IIFFFELYMVSIYKGAGNLLQVMLSMDYTTGLVITAVIVMVYTAIGGFRAVVMTDLIQGV 185

Query: 190 FMLLTLIIMPILALVEIGGLDRATQIIASV------------DPNKLHPFGGATGWAAIV 237
            +L+  + + +  +  +GG   A + +++             +  K+ P         + 
Sbjct: 186 IVLIGGVALFLTLIYSLGGFSSAIEALSNAKIFGEMVGKALFEIGKVGPPPIVKAGMIVP 245

Query: 238 FAIGYASWI-VGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFA 296
           F +     I V  L  P +V R+++  D R +   G+ ++ +   I     F  G  G+ 
Sbjct: 246 FVLSLTFAISVAQLASPQLVVRFVAARDSRVIAN-GMILTPLIIGIFAICVFSIGPFGWL 304

Query: 297 LVASGSIKV----EDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIA 352
           ++   +  V    +D + +VP +A+   P  +   ++  II+A MST +S + + ++A  
Sbjct: 305 VIPKYTDDVTQFLKDVDLVVPFIAMKLFPAGINALLLTAIIAAAMSTINSLIHLVATAFV 364

Query: 353 RDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGP 412
           RD+   V  +++ ++  +N++R  V   A + + FAI    VI ++V  ++  +   F  
Sbjct: 365 RDLVQNV--KKIEERTALNLTRFAVFIFATIPVIFAINPMGVIVEIVGVSFSVITSAFLV 422

Query: 413 ILTLSLWWKRVTKEAGIVGMAYGLISEVI---LEAKIYGWAFNPKAPG 457
            L   L+ ++    A    M   +++ V+      K+Y W + P  PG
Sbjct: 423 PLIACLYSEKPNSAAISASMVAAVLASVLWYFYYYKVY-WIY-PVVPG 468


>pir||F83241 probable sodium:solute symporter PA3234 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9949356|gb|AAG06622.1|AE004746_6 (AE004746) probable
           sodium:solute symporter [Pseudomonas aeruginosa]
           Length = 551
           
 Score =  138 bits (345), Expect = 1e-31
 Identities = 122/456 (26%), Positives = 201/456 (43%), Gaps = 28/456 (6%)

Query: 1   MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60
           +N   +  F+ ++     I +WA+K  ++   Y+  G ++      L+      S    L
Sbjct: 32  LNVSAIVMFVAFVGATLCITYWASKRNRSAADYYAAGGRITGFQNGLAIAGDYMSAASFL 91

Query: 61  GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTK 120
           G     F +G       IG L G      LI  RLR   GK+   T  D    RLK   K
Sbjct: 92  GISALVFTSGYDGLIYSIGFLVGWPIILFLIAERLR-NLGKY---TFADVASYRLKQ--K 145

Query: 121 LIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAV 180
            IR LSA   LV +  Y+ AQ    GK     F ++    +++  I++  YV+ GG  A 
Sbjct: 146 QIRTLSACGSLVVVAFYLIAQMVGAGKLIELLFGLNYHVAVVLVGILMVLYVLFGGMLAT 205

Query: 181 VWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPF-------GGATGW 233
            W  +++A+ +L     M I+ L  +   D +T    ++   K+HP        GG    
Sbjct: 206 TWVQIIKAVLLLSGASFMAIMVLKHV-NFDVSTLFSEAI---KVHPKGEAIMSPGGLVKD 261

Query: 234 AAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFL 293
               F++G+A  + G  G PHI+ R+ +V D ++ R+   + +G      +   F  GF 
Sbjct: 262 PISAFSLGFA-LMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYIL-TFIIGFG 319

Query: 294 GFALVASGSIKVEDPERIVPA--MAIHFLPGWVAGFVIAGIISAV-----MSTADSQLLV 346
              LV++     +    ++    MA   L   V G +  G ISAV     ++      L 
Sbjct: 320 AILLVSTNPDFKDATGALIGGNNMAAVHLADAVGGSLFLGFISAVAFATILAVVAGLTLA 379

Query: 347 ASSAIARDIYHKVL-GQELGKKQMVNISRIVVAAVALVAMWFAITGPKV-IYQMVATAWG 404
            +SA++ D+Y  V  G +  +K  + +S++   A+ +VA+   I   K  I  MV  A+ 
Sbjct: 380 GASAVSHDLYASVFKGGKANEKDELRVSKMTTVALGVVAIVLGILFEKQNIAFMVGLAFS 439

Query: 405 GLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEV 440
             A    P+L LS++WK++T    ++G   GLI+ V
Sbjct: 440 IAASCNFPVLLLSMYWKKLTTRGAMIGGWMGLITAV 475


>gi|11498821 proline permease (putP-3) [Archaeoglobus fulgidus]
           >gi|7483927|pir||E69402 proline permease (putP-3)
           homolog - Archaeoglobus fulgidus
           >gi|2649354|gb|AAB90016.1| (AE001019) proline permease
           (putP-3) [Archaeoglobus fulgidus]
           Length = 479
           
 Score =  138 bits (343), Expect = 2e-31
 Identities = 123/475 (25%), Positives = 210/475 (43%), Gaps = 54/475 (11%)

Query: 52  SDFSGWLMLGYPGSAFKAGLGAFWAGI-GCLFGTLADYLLIGPRLRIYAGKFRAITLPDY 110
           S FSG  ++G  G AF  G    W  I G  F      +LIG +L     K   +T+ DY
Sbjct: 23  SVFSGMTLIGVAGLAFTTGYANVWERIIGPPFAIAFGTILIGYKLFNLKDKNGILTIQDY 82

Query: 111 LEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTA 170
           L  R  D+ K+IRIL+  I  V    Y+  Q+ A G        +    G +I  +I+ A
Sbjct: 83  LAFRY-DDPKIIRILAGLISAVTCFVYLIGQYTAIGVVSYVVLGIPYWLGAVIAAVIVVA 141

Query: 171 YVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGA 230
           YV++GG F+  WT  +Q++ MLL + +     +  +GG +   Q +A++   +    G A
Sbjct: 142 YVMSGGMFSTAWTTFLQSILMLLGIYVTVPFIIAWVGGFEAMNQALAAMPEIQNATRGVA 201

Query: 231 TGWAAIVF--------AIGYASWI-----------VGYLGQPHIVTR---YMSVEDPR-- 266
             +    +        ++  A W+           +G +  PHIV     +  +E  R  
Sbjct: 202 ENFMFAKYLSKPFAPASVPLAGWVYNLTLFGITVPLGLMVAPHIVNNMLTFRKIEYTRWG 261

Query: 267 KLRRPGIFISGIWTT----IVLWGAFFAGFLGFALVASGSIKVEDPERIVPAMAIHFLPG 322
            L    I  S I+ T    +    A+  G +    +  GSI+V+  +   P +A   LP 
Sbjct: 262 PLVMYVIGFSAIFLTALAGMAARVAWAKGMIDIPSLTLGSIEVKWSDMAYPTIASKALPY 321

Query: 323 WVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVAL 382
           W+   ++  I++ VMST D  +L A++ I+ D+    LG+ L +  +  ++ +VV  +  
Sbjct: 322 WLFVLLLPTILAGVMSTTDRLILTAANNISYDVLRNALGKNLSENALKKVNMLVVPLIGF 381

Query: 383 VAMWFAITGPKVIYQMVATAWGGLAV----GFGPILTLSLWWKRVTKEAGIVGMAYGLIS 438
            ++  A+   +++   +   W  L++     F PI+ L L+W R+TK A  + M  G + 
Sbjct: 382 GSLLIALFPQQLLAWFI---WAALSLMTNCFFFPIM-LGLYWDRMTKNAARLSMIAGFVV 437

Query: 439 EVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFI--NFFVTLFIIIIVSLLTK 491
            +   A IYG                +  G+P + +   F  +  + + VSLL K
Sbjct: 438 TLATFA-IYGKTI-------------YIAGIPAYSVLPGFVASFVLAVGVSLLEK 478


>gi|11498574 proline permease (putP-2) [Archaeoglobus fulgidus]
           >gi|7442764|pir||A69371 proline permease (putP-2)
           homolog - Archaeoglobus fulgidus
           >gi|2649629|gb|AAB90273.1| (AE001037) proline permease
           (putP-2) [Archaeoglobus fulgidus]
           Length = 531
           
 Score =  137 bits (341), Expect = 4e-31
 Identities = 130/532 (24%), Positives = 218/532 (40%), Gaps = 47/532 (8%)

Query: 10  LIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKA 69
           ++Y + +  IG+++ +  K+   Y+V GR+V  +   L+ +++  S   MLG P   F  
Sbjct: 13  VLYFLAIIIIGYYSRQRLKSATDYYVAGRQVGAVVNGLALESTYLSPASMLGLPAYIFIL 72

Query: 70  GLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAAI 129
           G   +WA    + G     LL    LR YA      +  DY   R  D    +R L   +
Sbjct: 73  GYPFWWAMSAIIAGMPIATLLTASALRKYA----PTSFADYYADRYNDQR--LRWLVGIV 126

Query: 130 ILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAM 189
            ++    Y+                V    G+++  II+  YV+ GG  A  W    QA 
Sbjct: 127 TVIGAVLYITLSLVGMALFLLAVAKVPYIIGLIVGTIIVMLYVVWGGMIATSWNAAFQAF 186

Query: 190 FMLLTLIIMPILALVEIGGLDRATQIIAS---------VDPNKLHPFGGATGWAAIVFAI 240
            M +  +I   + ++++GGL    + + +          DP   H   G   W A++   
Sbjct: 187 LMTVAAVIAAAVIVIKLGGLGGFYEAVLANNPKFWNTPSDPEPPHLLSGT--WIAVIG-- 242

Query: 241 GYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVAS 300
            +  W  G+   P+ V R+ +  D +  RR  IF   +   I        G     ++ +
Sbjct: 243 WFFVWHYGFATMPYTVVRFFTTMDIKTARR-SIFWCTLAAGIFYMALEIIGAASKLMIET 301

Query: 301 GSIKVE--DPERIVPAMAIHFLPG-----------------WVAGFVIAGIISAVMSTAD 341
           G +  E  +  +I+ +    +  G                 WV G + AG ++  MSTA 
Sbjct: 302 GPMGGEGANAVKILQSYMAQYGVGGWTDYSMIAAVEALQNPWVLGILCAGGLAIAMSTAA 361

Query: 342 SQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVAT 401
             ++V ++ + RD    +L  +  K++ V ++RI+     +V    AI  P ++  +   
Sbjct: 362 GWVMVVNTLLTRDWGDMLLKSKFAKEKPVTLARIISVIFLIVGFLVAINPPGLVLDLSGW 421

Query: 402 AWGGLAVGFGPILTLSLWWKRVTKEA----GIVGMAYGLISEVILEAKIYGWAFNPKAPG 457
           A+  +    GP L L LWWKR T+ A     IV     L + +  +  +   AF      
Sbjct: 422 AFVVIISALGPGLVLGLWWKRATRAAMWTTAIVMTPLHLYAWLKAKLVLGHHAFFFLNDV 481

Query: 458 FFGTLGQWFNGVPVFFINFFVTLFIIIIVSLLTKPPED--VVKLHEELFKKV 507
            FG          V+ I   V   + IIVSL+TKP E+  V K   EL K+V
Sbjct: 482 LFGNAKALITPHQVWAIP--VGFLLFIIVSLITKPVEEEAVQKYCVELTKEV 531


>pir||H71097 hypothetical protein PH1044 - Pyrococcus horikoshii
           >gi|3257459|dbj|BAA30142.1| (AP000004) 491aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 491
           
 Score =  134 bits (335), Expect = 2e-30
 Identities = 134/506 (26%), Positives = 231/506 (45%), Gaps = 45/506 (8%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           I+ G++   +I+  +     K+T   + Y V GR + ++   +      +S +  LG  G
Sbjct: 19  IVLGWVFLSLIVGVMAGIKRKFTL--EGYLVSGRTLGLIFLYVLMAGEIYSAYAFLGTGG 76

Query: 65  SAFKAGLGAFWAGIGCLFGTLA-DYLLIGPRLRIYAGK-FRAITLPDYLEARLKDNTKLI 122
            A+  G+   +A IG  +G LA  +     R    AGK F  +T  DY + R   N+K +
Sbjct: 77  WAYSYGMPIMYA-IG--YGALAYSFGYFYARYVWKAGKAFGCVTQADYFQVRY--NSKAL 131

Query: 123 RILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVT--TGILITVIILTAYVITGGFFAV 180
            +L A I ++F   Y+  Q    G         S+T   GI+I +II+  YV T G   +
Sbjct: 132 AVLVALIGIIFNIPYLQLQLQGLGYIVHVGSLGSITPKAGIVIGMIIMMIYVYTSGLRGI 191

Query: 181 VWTDVVQAMFM-LLTLIIMPILALVEIGGLDRATQIIASVDPNK--LHPFGGATGWAAIV 237
            WT+++QA  M ++  +++  +   + GG+    + +A   P+   LHP  G + + + +
Sbjct: 192 SWTNLLQATLMFIVAWVVLFTIPFKQFGGIGELFKTLAQTKPDHLILHPPLGISWYVSTL 251

Query: 238 FAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFAL 297
              G     +G+   P +        D + L+R  + +     +I +     AGF     
Sbjct: 252 ILSG-----LGFFMYPQLYPSIYGARDLKTLKRNYVLLP--LYSIFMIPVILAGF----T 300

Query: 298 VASGSIKVEDP-ERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIY 356
           VA+  IK+  P E ++ A+ I + P WV G V A   +A  STA + LL  +  +++++Y
Sbjct: 301 VAALGIKLSAPDEAVLKAVEITY-PSWVLGVVGAAGFAAAASTASAILLSLAGLLSKNLY 359

Query: 357 HKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTL 416
             +       K++V +SRI V  + L+AM  A+  P  +  ++  A+ G+   F P    
Sbjct: 360 -AIAKPTASDKELVLVSRISVILLGLLAMGLALYSPGRLVSLLLLAYAGMTQMF-PGAVF 417

Query: 417 SLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINF 476
            L+WKR+ K A   G+  GLI+   L   +     NP    F    G W           
Sbjct: 418 GLFWKRMNKYATGTGIIAGLITVAYLRLVL---KKNPLGIHF----GLW---------GL 461

Query: 477 FVTLFIIIIVSLLTKPPEDVVKLHEE 502
            V + + +IV+ LTKP E++    +E
Sbjct: 462 LVNIIVTLIVAYLTKPEEELFTRFKE 487


>sp|P32705|YJCG_ECOLI HYPOTHETICAL 59.2 KD PROTEIN IN SOXR-ACS INTERGENIC REGION (F549)
           >gi|7442761|pir||B65215 hypothetical 59.2 kD protein in
           soxR-acs intergenic region - Escherichia coli (strain
           K-12) >gi|396402|gb|AAC43161.1| (U00006) similar to
           Salmonella proline permease [Escherichia coli]
           >gi|1790503|gb|AAC77037.1| (AE000480) putative transport
           protein [Escherichia coli K12]
           Length = 549
           
 Score =  134 bits (334), Expect = 2e-30
 Identities = 113/452 (25%), Positives = 195/452 (43%), Gaps = 19/452 (4%)

Query: 2   NFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLG 61
           N+  +  FLI++V    I +WA+K  ++   Y+  G  +      L+      S    LG
Sbjct: 32  NWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLG 91

Query: 62  YPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKL 121
                F +G       +G L G      LI  RLR   G++   T  D    RLK     
Sbjct: 92  ISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLR-NLGRY---TFADVASYRLKQGP-- 145

Query: 122 IRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVV 181
           IRILSA   LV +  Y+ AQ    GK     F ++    +++  +++  YV+ GG  A  
Sbjct: 146 IRILSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATT 205

Query: 182 WTDVVQAMFMLLTLIIMPILALVEIG-GLDRATQIIASVDPNKLHPF--GGATGWAAIVF 238
           W  +++A+ +L     M  + +  +G   +       +V P  +     GG         
Sbjct: 206 WVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISAL 265

Query: 239 AIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALV 298
           ++G    + G  G PHI+ R+ +V D R+ R+   + +G      +   F  GF    LV
Sbjct: 266 SLG-LGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYIL-TFIIGFGAIMLV 323

Query: 299 ASGSIKVEDPERIVPA--MAIHFLPGWVAGFVIAGIISAV-----MSTADSQLLVASSAI 351
            +     +    ++    MA   L   V G +  G ISAV     ++      L  +SA+
Sbjct: 324 GANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAV 383

Query: 352 ARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAIT-GPKVIYQMVATAWGGLAVGF 410
           + D+Y  V  +   +++ + +S+I V  + ++A+   +    + I  MV  A+   A   
Sbjct: 384 SHDLYANVFKKGATEREELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCN 443

Query: 411 GPILTLSLWWKRVTKEAGIVGMAYGLISEVIL 442
            PI+ LS++W ++T    ++G   GLI+ V+L
Sbjct: 444 FPIILLSMYWSKLTTRGAMMGGWLGLITAVVL 475


>pir||E70480 probable sodium/proline symporter ssf [similarity] - Aquifex
           aeolicus >gi|2984319|gb|AAC07841.1| (AE000773)
           Na(+):solute symporter (Ssf family) [Aquifex aeolicus]
           Length = 487
           
 Score =  134 bits (334), Expect = 2e-30
 Identities = 128/496 (25%), Positives = 217/496 (42%), Gaps = 76/496 (15%)

Query: 63  PGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLI 122
           P S +++ L      +  + G    Y+L+   +  Y  KF   T+PD++  R + N   +
Sbjct: 4   PSSVWRSTLRPRVRRLAYIMGWTGGYVLLALLIAPYLRKFGKFTVPDFIAERYESNFARL 63

Query: 123 RILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVW 182
             L  AII+ F   Y+  Q A  G    + F V    GI I +I++ A  + GG  ++ W
Sbjct: 64  VALIIAIIISF--TYMVGQVAGVGIIMGRLFGVPFEIGIAIGMIVIIATTVLGGMKSITW 121

Query: 183 TDVVQAMFMLLTLIIMPI-LALVEIGGLDRATQIIASV-------------DPNKLHPFG 228
           T V Q + +L+T  ++P+ L  ++  G+     +  +V              P+ + P+ 
Sbjct: 122 TQVAQYI-VLITAYLLPVSLLAMQWFGIPLPQFLYGNVLQWIVDLEKQHGISPHYIEPYV 180

Query: 229 --GATGWAAIVFAIGYASWIVGYLGQPHIVTRYM---SVEDPRKLRRPGIFISGIWTTIV 283
                 + A++F +     + G    PH++ R+    SV+D R      +F   I   + 
Sbjct: 181 KFNMIQFLALMFVL-----MAGTAALPHVLMRFFTTPSVKDARWSAGWALFFIAI---LY 232

Query: 284 LWGAFFAGFLGFALVA-------------------SGSIKVEDPE-------------RI 311
           L    +A F  + ++                    +G  KV D               R 
Sbjct: 233 LTAPAYAAFARYVVLKDVVGKPIDQLPAWAQKWAETGLFKVIDQNGDGIIQWAELQLHRD 292

Query: 312 VPAMAIHFLPGW---VAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQ 368
           +  +A   + G    V  FV+AG ++A +STAD  LLV ++A++ D+Y K++     +K+
Sbjct: 293 IVVLATPEIAGLSLLVGYFVMAGGLAAALSTADGLLLVIAAAVSNDLYAKMINPNAPEKK 352

Query: 369 MVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAG 428
           +V + +I VA   ++  + A      I Q+VA A+      F P L L ++WKR+ KE  
Sbjct: 353 IVMLGKIAVAVAGVIGGFVAAMKIGFIVQIVAWAFSLATASFFPALVLGIFWKRLNKEGA 412

Query: 429 IVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTLFIIIIVSL 488
           I GM  GL+  +I       + +  K  G F  LG       VF     V L +  IV++
Sbjct: 413 IAGMVAGLLVTII-------YIYLNKTQG-FSILGIQHTASGVF--GLLVNLIVSYIVTM 462

Query: 489 LTKPP-EDVVKLHEEL 503
           +T PP E V KL E++
Sbjct: 463 MTPPPSERVQKLVEDI 478


>gb|AAG20007.1| (AE005081) pantothenate permease; PanF [Halobacterium sp. NRC-1]
           Length = 482
           
 Score =  128 bits (319), Expect = 1e-28
 Identities = 121/462 (26%), Positives = 201/462 (43%), Gaps = 44/462 (9%)

Query: 13  LVILAYIGWWANKYTKTE-DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGL 71
           +V+   +G  A + T  + + Y++ GR +       +  A+  S +     P  A+  G 
Sbjct: 1   MVVALAVGLVAYRVTDRDAEDYYLAGRGLGTGVLLFTTFATLLSAFTFFAGPNIAYANG- 59

Query: 72  GAFWAGI-----GCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILS 126
              W  +     G LFG L  + ++G R  +       +TL + L  R    ++ +R L 
Sbjct: 60  -PEWILVMGLMDGVLFGLL--WYVLGYRQWLLGKANGYVTLGEMLGDRF--GSRGLRGLV 114

Query: 127 AAIILVFMTAYVAAQFAAGGKTFAQAFNVSVT--TGILITVIILTAYVITGGFFAVVWTD 184
           A + + ++  YV  Q    G+        +V    G     + +  YV   G   V WTD
Sbjct: 115 AGVSIFWLFPYVMLQQIGAGEALVGLTGGAVPYWAGAGFITLFMVVYVAISGMRGVAWTD 174

Query: 185 VVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGAT---GWAAIVFAIG 241
            +Q +FML    +  +    EI G    T  +A   P +    GG      W  +  AIG
Sbjct: 175 TLQGVFMLGITWVAFVWVAAEIAG---TTGGLAGALPAEFRALGGGAYSPQWM-LSQAIG 230

Query: 242 YASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVASG 301
            A   VG    P +  R+   +  R L+R       IW  +V+   F   FL  A     
Sbjct: 231 IA---VGVSMFPQVNQRFFVADSKRTLKRT----FAIWPLLVVL-LFVPAFLMGAWANGV 282

Query: 302 SIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLG 361
            + + D E IVP +   + PGW A  V+AG ++A+MS++DS LL  SS   RDIY   + 
Sbjct: 283 GLPLPDGENIVPILLSEYTPGWFAALVVAGALAAMMSSSDSMLLSGSSYFTRDIYRPFVN 342

Query: 362 QELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWK 421
            +   ++   + R+ VAA A+ A   ++  P  + ++ +TA+GG A    P + L+++W+
Sbjct: 343 ADATARREDTLGRVGVAAFAVAAFGGSLLRPGSLLEVGSTAFGGFA-QLAPPVALAMYWR 401

Query: 422 RVTKE---AGIVGMAYGLISEV-----------ILEAKIYGW 449
           R TK    AG++G     ++ V           I+ +  +GW
Sbjct: 402 RTTKAGMFAGVLGTQAFYLATVFGPPVTLAGVPIIASSYFGW 443


>pir||E82043 probable sodium/solute symporter VC2705 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9657301|gb|AAF95845.1| (AE004336) sodium/solute
           symporter, putative [Vibrio cholerae]
           Length = 506
           
 Score =  124 bits (309), Expect = 2e-27
 Identities = 125/484 (25%), Positives = 197/484 (39%), Gaps = 81/484 (16%)

Query: 69  AGLGAF--WAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILS 126
           AG+ +F  + G   L G    Y+L+   L  Y  KF   T+PD++  R    T  +  + 
Sbjct: 2   AGIISFIGYDGTVYLMGWTGGYVLLALCLAPYLRKFGKFTVPDFIGDRYYSRTARMVAVF 61

Query: 127 AAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVV 186
            AI + F   YVA Q    G  FA+   V +  GI+I + I+  Y + GG   + +T V 
Sbjct: 62  CAIFISF--TYVAGQMRGVGVVFARFLEVDINVGIVIGMAIVFFYAVMGGMKGITYTQVA 119

Query: 187 QAMFMLLTLIIMPILALVEIGGLDRATQI-----IASVDP---NKLHPFGGATGWAAI-- 236
           Q   ++   ++  I   + + G +   QI     +   D    NKL       G+ A   
Sbjct: 120 QYCVLIFAFLVPAIFTSLMMTG-NPIPQIGFGSTLTGTDDYLLNKLDGLAVELGFTAYTD 178

Query: 237 -------VFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPG----IFISGIWTTIVLW 285
                  VF I  A+ +VG  G PH++ R+ +V      R       +FI+ ++TT    
Sbjct: 179 GSKSMVDVFFI-CAALMVGTAGLPHVIIRFFTVPKVSDARVSAGWALVFIAFLYTTAPAV 237

Query: 286 GAFFA-----------------------------------------GFLGFALVASGSIK 304
            AF                                           G + ++  A   + 
Sbjct: 238 AAFARVNMIDTINGPDMQGVTAAEAPTWYRNWESTGLVKWEDKNGDGRMFYSGDARNEMT 297

Query: 305 VEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQEL 364
           + +   ++ +  I  LP WV   + AG ++A +STA   LLV S+AI+ D+  K    ++
Sbjct: 298 INNDIIVLASPEIAKLPNWVVALLAAGGLAAALSTAAGLLLVISTAISHDLLKKGFKPDM 357

Query: 365 GKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVT 424
             KQ +  +RI  A   + A +  I  P  + Q+VA A+G  A  F P + L +++K++ 
Sbjct: 358 TDKQELLAARIAAALAIVGAGYLGINPPGFVAQVVAFAFGLAAASFFPAIILGIFYKKMN 417

Query: 425 KEAGIVGMAYGLISEVILEAKIYGWAFNPKA-----------PGFFGTLGQWFNGVPVFF 473
           KE  I+GM  G+         IY    NP A           P   GTLG   N V    
Sbjct: 418 KEGAIIGMLAGITFTAAY--IIYFKFINPAASVPANWWFGISPEGIGTLGMCLNFVVAIV 475

Query: 474 INFF 477
           +N F
Sbjct: 476 VNKF 479


>pir||S52839 dhlC protein - Xanthobacter autotrophicus
           >gi|763398|emb|CAA60038.1| (X86084) dhlC [Xanthobacter
           autotrophicus]
           Length = 516
           
 Score =  124 bits (308), Expect = 3e-27
 Identities = 125/491 (25%), Positives = 208/491 (41%), Gaps = 40/491 (8%)

Query: 6   LFGFLIYLVILAY---IGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGY 62
           L    I++ ILA    I WWA + T+T   ++     +  +    +      S    LG+
Sbjct: 3   LLALAIFVAILALTLAITWWAARRTRTASDFYTADGTLGPIQNGFALAGDWMSAAAFLGF 62

Query: 63  PGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARL-KDNTKL 121
            G A   G+       G L   LA  +L+   +R   G+F   TL D +  R+ +   +L
Sbjct: 63  SGLAALYGMDGSLYAAGALVAFLAILMLVAEPIR-NTGRF---TLGDVIAFRMQRPQARL 118

Query: 122 IRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVV 181
             +L   ++ +   AY+  Q A G         V     I++  + +  YV+ GG  A  
Sbjct: 119 AAVLGTVVVSL---AYLVPQMAGGAALIKLLLGVPYAISIVVVGLGMLVYVVFGGMIATT 175

Query: 182 WTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDP--NKLHPFGGATGWAAIVFA 239
           W  +++A+ +L    ++  L L    G D  +   A+ D    K+   G          +
Sbjct: 176 WVQIIKAVMLLSAAAVLVALLLAHF-GFDPFSVFAAAEDTYGAKILAPGNYLKHPLDQLS 234

Query: 240 IGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFF-----AGFLG 294
           +G  S+  G  G PH++TR+ +V D +  RR     S +W  + L G+FF      G   
Sbjct: 235 LG-LSFAFGTAGLPHVMTRFYTVPDAQTARR-----SAVW-LMFLAGSFFLVTTLIGLGS 287

Query: 295 FALVASGSIKVEDP--ERIVPAMAIHF--LPGWVAGFVIAGIISAV-----MSTADSQLL 345
             LV   +I+  D      +P +A H    P  + G V   ++ AV     ++   +  L
Sbjct: 288 AVLVGQDAIRAADKGGNLALPLLAQHLGGGPDSIGGQVFLAVVVAVAFATILAVVAALTL 347

Query: 346 VASSAIARDIYHKVL-GQELGKKQMVNISRIVVAAVALVAMWFAITGPKV-IYQMVATAW 403
             S AIA D+Y  VL G  + +++ V ++RI    V+  A+ F +    + +  +V  A 
Sbjct: 348 STSGAIAHDLYVNVLRGGHVSEQEQVKVARISTVIVSAFAILFGLLAQGINVAVLVILAI 407

Query: 404 GGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLG 463
              A    P++ LSL+W+R      + GM  GL+S V L   + G AF   A   F  + 
Sbjct: 408 SVAASANFPVIVLSLFWQRFNTAGVVTGMVAGLVSAVAL--ALTGPAF-MGADALFPVVN 464

Query: 464 QWFNGVPVFFI 474
                VP+ F+
Sbjct: 465 PAIASVPIGFL 475


>sp|P39599|YWCA_BACSU HYPOTHETICAL 55.0 KD PROTEIN IN EPR-GALK INTERGENIC REGION
           >gi|7442759|pir||S39686 Na+-dependent symport homolog
           ywcA - Bacillus subtilis >gi|580869|emb|CAA51587.1|
           (X73124) ipa-31r [Bacillus subtilis]
           >gi|2636359|emb|CAB15850.1| (Z99123) alternate gene
           name: ipa-31r~similar to Na+-dependent symport [Bacillus
           subtilis]
           Length = 516
           
 Score =  122 bits (302), Expect = 1e-26
 Identities = 108/435 (24%), Positives = 195/435 (44%), Gaps = 19/435 (4%)

Query: 17  AYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWA 76
           AY   +  K TKT  +++  G  +  +   L+      S    LG  G     G   F+ 
Sbjct: 20  AYYHVFCAKRTKTTSEFYTAGGGLTGVQNGLAIAGDYMSAASFLGIAGMIALYGFDGFFY 79

Query: 77  GIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTA 136
            IG L   L    ++   LR   GK+   T+ D + AR K+  K IR ++A   +   T 
Sbjct: 80  SIGFLVAYLVVLYIVAEPLR-NLGKY---TMADMIAARFKE--KKIRGVAALNTIAISTF 133

Query: 137 YVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLI 196
           Y+ AQ    G        +  T  +LI  +++T YV+ GG  A  W  +++A+ ++   +
Sbjct: 134 YMIAQLVGAGALIKLLLGLDYTAAVLIVGVLMTIYVVFGGMIATSWVQIIKAVLLMAGTL 193

Query: 197 IMPILALVEIG-GLDRATQIIASVDP---NKLHPFGGATGWAAIVFAIGYASWIVGYLGQ 252
           ++ I+   + G  L+   + + +  P   + L+P G          ++  A  ++G  G 
Sbjct: 194 VISIIVFSKFGFSLNTMFEQMKTATPLGADFLNP-GNKYKVPLETLSLNLA-LVLGTAGL 251

Query: 253 PHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLW-GAFFAGFLGFALVASGSIKVEDP--E 309
           PHI+ R+ +V+D +  R     +S  W   V +    F GF   A V   +I   D    
Sbjct: 252 PHILIRFYTVKDAKTARTS--VVSATWIIGVFYIMTVFLGFGAAAFVGFDAITAADQAGN 309

Query: 310 RIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQ-ELGKKQ 368
              P +A      ++  FV A   + +++     +L A+SA A DIY +++ + E  +K+
Sbjct: 310 MAAPLLAKALGGDFLFAFVSAIAFATILAVVTGLVLSAASAFAHDIYSQIIRKGEATEKE 369

Query: 369 MVNISRIVVAAVALVAMWFAITGPKV-IYQMVATAWGGLAVGFGPILTLSLWWKRVTKEA 427
            +  +R    AV+++++  AI    + +  +VA A+   A    P++  +++WKR     
Sbjct: 370 QMKAARWASVAVSVLSILLAIFAQSLNVAFLVALAFAVAASANLPLIVFTVFWKRFNASG 429

Query: 428 GIVGMAYGLISEVIL 442
            + G   GLIS ++L
Sbjct: 430 ALWGSLTGLISALVL 444


>gi|11497853 pantothenate permease (panF-3) [Archaeoglobus fulgidus]
           >gi|7442769|pir||E69279 pantothenate permease (panF-3)
           homolog - Archaeoglobus fulgidus
           >gi|2650404|gb|AAB90996.1| (AE001089) pantothenate
           permease (panF-3) [Archaeoglobus fulgidus]
           Length = 461
           
 Score =  118 bits (294), Expect = 1e-25
 Identities = 114/450 (25%), Positives = 197/450 (43%), Gaps = 43/450 (9%)

Query: 6   LFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65
           L+ F+ Y++I   I   A K  +T+++Y++ GRKV  + + L+  A+ +S ++M+G  G 
Sbjct: 8   LYAFIGYIIIGTAIAIMAMKGLRTQEEYYIAGRKVSGVISALTYAATTYSAFMMVGLVGL 67

Query: 66  AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRIL 125
           ++ +G+GA    +  L GTL       PR+   A +   +T  D +  R       +  L
Sbjct: 68  SYFSGVGALGFELFYLVGTLFLLSYYAPRVWEMAKERGYVTPGDMIAERYGSE---VAKL 124

Query: 126 SAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDV 185
            A I+ + +  Y++ Q        ++   +S   GI+ + I++  +   GG   V WTD 
Sbjct: 125 MAVIVSIALIPYISVQLIGVSLILSKTNAMSFEAGIVASAILIALWAFLGGLRGVAWTDA 184

Query: 186 VQAMFMLLTLIIMPILALVEIGGLDRATQIIAS------VDPNKLHPFGGATGWAAIVFA 239
           +Q +FMLL + I  IL + + G  ++      S      V PN +        W  + F 
Sbjct: 185 LQGVFMLL-MAIAAILWVHQYGFAEKDFFTEVSRLGELLVVPNSI--------WTPVKFI 235

Query: 240 IGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGI---FISGIWTTIVLWGAFFAGFLGFA 296
                W    L  P +  R    +D   LRR  I   F   I+T IV         +G  
Sbjct: 236 SLTLPWFFFALTNPQVFQRLYIPKDRSALRRMVILFGFFGLIYTVIVT-------LIGLE 288

Query: 297 LVASGSI----KVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIA 352
           L     +    KV D + + P M +  +P  +   +   I +A ++TA+S +L  SS I 
Sbjct: 289 LRTMTEMGVFPKVPDRDAVTPTM-LAMMPPLLGAAISLSIFAAAITTANSIVLTLSSMIT 347

Query: 353 RDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGP 412
           RD+    LG E      V   R+++  + +    FA + P  I ++   +   L     P
Sbjct: 348 RDL----LGSE-----KVGSGRVLIVILTVAVALFAYSRPGYIVELSVLSSTILLCQL-P 397

Query: 413 ILTLSLWWKRVTKEAGIVGMAYGLISEVIL 442
           ++       R  + AGI  ++ G I+ V+L
Sbjct: 398 LILGVFHLNRGGRLAGIATLSAGFITAVVL 427


>pir||C82582 Na+-dependent symport homolog XF2251 [imported] - Xylella
           fastidiosa (strain 9a5c)
           >gi|9107405|gb|AAF85050.1|AE004037_11 (AE004037)
           solute:Na+ symporter [Xylella fastidiosa]
           Length = 577
           
 Score =  116 bits (289), Expect = 5e-25
 Identities = 108/471 (22%), Positives = 200/471 (41%), Gaps = 35/471 (7%)

Query: 1   MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60
           +N+ ++  F+++++I  +I  WA K T++   ++  G  +      L+      S    L
Sbjct: 34  VNWVVISIFVVFVLITLWITKWAAKRTRSSADFYTAGGTITGFQNGLAMAGDYMSAAAFL 93

Query: 61  GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTK 120
           G   +   +G       IG L G      L+  RLR   GK+    +  Y  A +     
Sbjct: 94  GITSAVMISGYDGMLYAIGSLVGWPILVFLVAERLR-NLGKYTFADVVAYRFAAVP---- 148

Query: 121 LIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAV 180
            +R+ ++A  LV +   + AQ    G      F +     +++   ++  YV+ GG  A 
Sbjct: 149 -VRLFTSASTLVVVLCSLVAQMVGAGALIKLLFGLDYWVAVILVGGLMMVYVMFGGMAAT 207

Query: 181 VWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAI 240
            W  +++A+ +L  L  M ++ +   G         A     ++   GG +G  A    +
Sbjct: 208 TWVQIIKAVLLLTCLTFMAVMIMWRFGFNFEGLFASAVGVKTQIAMAGGKSGEEAKALGL 267

Query: 241 GY-----------------ASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIF-ISGIWTTI 282
                               + + G +G PHI+ R+ +V D R++R   ++ I+ I    
Sbjct: 268 SIMAPGSFIKDPISAISLGIALVFGNVGLPHILMRFFAVPDAREVRHSVLWAITWIGYCY 327

Query: 283 VLWGAFFAGFLGFAL-------VASGSIKVEDPERIVPAMAIHFLPGW--VAGFVIAGII 333
           +L      G + F L       +A+G+I+       + A+ +  + G     GFV A   
Sbjct: 328 ILMFIVGFGAIVFVLTNPQYADIATGTIRGGQGAANMAAVLVAKVVGGDVFMGFVSAVAF 387

Query: 334 SAVMSTADSQLLVASSAIARDIYHKVLGQ-ELGKKQMVNISRIVVAAVALVAMWFAITGP 392
           + +++ A    L  +SA++ D+Y  V+ Q +      + +SR+  A + +VA+   I   
Sbjct: 388 ATILAVAAGLALSGASAVSHDVYAMVIKQGKPSSDTELLVSRVTTAVLGVVAVLLGIVFQ 447

Query: 393 KV-IYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVIL 442
           K  +  MV+ A+   A    P+L LSL WK  T    ++G   GLIS ++L
Sbjct: 448 KQNVAFMVSLAFAIAASANFPVLILSLLWKNCTTWGAVIGGFLGLISSLVL 498


>emb|CAA94864.1| (Z71176) phenylacetic acid permease [Pseudomonas putida]
           >gi|3253206|gb|AAC24338.1| (AF029714) PhaJ [Pseudomonas
           putida]
           Length = 520
           
 Score =  113 bits (281), Expect = 4e-24
 Identities = 111/459 (24%), Positives = 190/459 (41%), Gaps = 30/459 (6%)

Query: 1   MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60
           MN+  +  F++++     +  WA   T++   ++  G  +  +   L+      S    L
Sbjct: 1   MNWTAISMFMVFVCFTLLVTRWAALRTRSASDFYTAGGGLTGMQNGLAIAGDMISAASFL 60

Query: 61  GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTK 120
           G     F  G       +G L G      LI  RLR   GK+   T  D +  RL     
Sbjct: 61  GISAMMFMNGYDGLLYALGVLAGWPIILFLIAERLR-NLGKY---TFADVVSYRLAQTP- 115

Query: 121 LIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAV 180
            +R+ SA   LV    Y+ AQ    GK     F +S    +++  +++ AYV  GG  A 
Sbjct: 116 -VRLTSAFGTLVVALMYLVAQMVGAGKLIELLFGISYLYAVMLVGVLMVAYVTFGGMLAT 174

Query: 181 VWTDVVQAMFMLLTLIIMPILALVEIGGLDR---ATQIIASVDPNKLHPFGGATGWAAIV 237
            W  +++A+ +L     M  + L   G       A+ +        +   GG        
Sbjct: 175 TWVQIIKAVMLLSGTSFMAFMVLKHFGFSTEAMFASAVAVHAKGQAIMAPGGLLSNPVDA 234

Query: 238 FAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFAL 297
            ++G    + G  G PHI+ R+ +V D ++ R+   + +G      L      GF    +
Sbjct: 235 ISLG-LGMMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYLL-LIVIGFGAIVM 292

Query: 298 VASGSIKVEDPERIVPA---MAIHFLPGWVAGFVIAGIISAV-----MSTADSQLLVASS 349
           V +     +    I+     +A+H L   V G +  G ISAV     ++      L  +S
Sbjct: 293 VGTEPSYRDATGAIIGGGNMIAVH-LAQAVGGNLFLGFISAVAFATILAVVAGLALSGAS 351

Query: 350 AIARDIYHKVLGQ-ELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWG---- 404
           A++ D+Y  V+ Q +  +++ + +SRI    + L+A+   + G     Q +A   G    
Sbjct: 352 AVSHDLYACVIRQGKATEQEEMRVSRIATLLIGLLAV---LLGLMFESQNIAFLSGLVLA 408

Query: 405 -GLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVIL 442
              +V F P+L LS++WK +T    + G   GL S V+L
Sbjct: 409 VAASVNF-PVLLLSMFWKGLTTRGAVCGSMAGLASAVLL 446


>sp|P96169|SGLT_VIBPA SODIUM/GLUCOSE COTRANSPORTER (NA(+)/GLUCOSE SYMPORTER)
           >gi|8886895|gb|AAF80602.1|AF255301_1 (AF255301)
           Na+/galactose cotransporter SGLT [Vibrio
           parahaemolyticus]
           Length = 543
           
 Score =  109 bits (270), Expect = 8e-23
 Identities = 107/471 (22%), Positives = 194/471 (40%), Gaps = 57/471 (12%)

Query: 1   MNFGILFGFLIYLVILAYIGWWANKYTK-----TEDQYFVGGRKVHVLAATLSDKASDFS 55
           ++F  +  F IY+ I+  +G W ++  K     TED YF+ G+ +   A   S  A++ S
Sbjct: 8   LSFIDIMVFAIYVAIIIGVGLWVSRDKKGTQKSTED-YFLAGKSLPWWAVGASLIAANIS 66

Query: 56  GWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKF--------RAITL 107
               +G  GS +  GL             +A Y  +     I  GK+           T+
Sbjct: 67  AEQFIGMSGSGYSIGLA------------IASYEWMSAITLIIVGKYFLPIFIEKGIYTI 114

Query: 108 PDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVII 167
           P+++E R   N KL  IL+   I +++   + +    GG        + +   IL   + 
Sbjct: 115 PEFVEKRF--NKKLKTILAVFWISLYIFVNLTSVLYLGGLALETILGIPLMYSILGLALF 172

Query: 168 LTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDR-ATQIIASVDPNKLH- 225
              Y I GG  AVVWTDV+Q  F++L   +   +A+  IGG D     +   VD    H 
Sbjct: 173 ALVYSIYGGLSAVVWTDVIQVFFLVLGGFMTTYMAVSFIGGTDGWFAGVSKMVDAAPGHF 232

Query: 226 ---------PFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFIS 276
                     +    G A ++  +  A+       Q +I+ R ++ +   + ++ GI  +
Sbjct: 233 EMILDQSNPQYMNLPGIAVLIGGLWVANLYYWGFNQ-YIIQRTLAAKSVSEAQK-GIVFA 290

Query: 277 GIWTTIVLWGAFFAGFLGFALVASGSI-------------KVEDPERIVPAMAIHFLPGW 323
                IV +     G   + + +   +                + ++  P +   FLP  
Sbjct: 291 AFLKLIVPFLVVLPGIAAYVITSDPQLMASLGDIAATNLPSAANADKAYPWLT-QFLPVG 349

Query: 324 VAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALV 383
           V G V A + +A++S+  S L   ++    DIY + +  + G  ++VN+ R       ++
Sbjct: 350 VKGVVFAALAAAIVSSLASMLNSTATIFTMDIYKEYISPDSGDHKLVNVGRTAAVVALII 409

Query: 384 AMWFA--ITGPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGM 432
           A   A  + G    +Q +    G ++ G   +  L L+WK+ T +  I+G+
Sbjct: 410 ACLIAPMLGGIGQAFQYIQEYTGLVSPGILAVFLLGLFWKKTTSKGAIIGV 460


>dbj|BAA11215.1| (D78137) Na+/glucose symporter [Vibrio parahaemolyticus]
           Length = 530
           
 Score =  109 bits (269), Expect = 1e-22
 Identities = 106/463 (22%), Positives = 190/463 (40%), Gaps = 57/463 (12%)

Query: 9   FLIYLVILAYIGWWANKYTK-----TEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYP 63
           F IY+ I+  +G W ++  K     TED YF+ G+ +   A   S  A++ S    +G  
Sbjct: 3   FAIYVAIIIGVGLWVSRDKKGTQKSTED-YFLAGKSLPWWAVGASLIAANISAEQFIGMS 61

Query: 64  GSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKF--------RAITLPDYLEARL 115
           GS +  GL             +A Y  +     I  GK+           T+P+++E R 
Sbjct: 62  GSGYSIGLA------------IASYEWMSAITLIIVGKYFLPIFIEKGIYTIPEFVEKRF 109

Query: 116 KDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITG 175
             N KL  IL+   I +++   + +    GG        + +   IL   +    Y I G
Sbjct: 110 --NKKLKTILAVFWISLYIFVNLTSVLYLGGLALETILGIPLMYSILGLALFALVYSIYG 167

Query: 176 GFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDR-ATQIIASVDPNKLH--------- 225
           G  AVVWTDV+Q  F++L   +   +A+  IGG D     +   VD    H         
Sbjct: 168 GLSAVVWTDVIQVFFLVLGGFMTTYMAVSFIGGTDGWFAGVSKMVDAAPGHFEMILDQSN 227

Query: 226 -PFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVL 284
             +    G A ++  +  A+       Q +I+ R ++ +   + ++ GI  +     IV 
Sbjct: 228 PQYMNLPGIAVLIGGLWVANLYYWGFNQ-YIIQRTLAAKSVSEAQK-GIVFAAFLKLIVP 285

Query: 285 WGAFFAGFLGFALVASGSI-------------KVEDPERIVPAMAIHFLPGWVAGFVIAG 331
           +     G   + + +   +                + ++  P +   FLP  V G V A 
Sbjct: 286 FLVVLPGIAAYVITSDPQLMASLGDIAATNLPSAANADKAYPWLT-QFLPVGVKGVVFAA 344

Query: 332 IISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFA--I 389
           + +A++S+  S L   ++    DIY + +  + G  ++VN+ R       ++A   A  +
Sbjct: 345 LAAAIVSSLASMLNSTATIFTMDIYKEYISPDSGDHKLVNVGRTAAVVALIIACLIAPML 404

Query: 390 TGPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGM 432
            G    +Q +    G ++ G   +  L L+WK+ T +  I+G+
Sbjct: 405 GGIGQAFQYIQEYTGLVSPGILAVFLLGLFWKKTTSKGAIIGV 447


>pir||S75887 hypothetical protein - Synechocystis sp. (strain PCC 6803)
           >gi|1653432|dbj|BAA18346.1| (D90913) sodium-coupled
           permease [Synechocystis sp.]
           Length = 512
           
 Score =  108 bits (268), Expect = 1e-22
 Identities = 117/460 (25%), Positives = 197/460 (42%), Gaps = 33/460 (7%)

Query: 10  LIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKA 69
           L+Y  I+  IG  A++     D+YF G +++   A   S  A+ FS   +LG PG  +  
Sbjct: 10  LVYSAIVIAIGAIASRKQDNTDEYFRGAKQIPWWALGFSIIATSFSAASLLGGPGEGYGH 69

Query: 70  GLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAAI 129
           G       +G L G    Y L+      +  +    T  +YLE R    T   R L +  
Sbjct: 70  GFLYLQLQLGDLIG----YGLVIAVFLPFFVRLNLTTAYEYLERRFDAKT---RSLGSLC 122

Query: 130 ILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQ-- 187
            L+F+ A +     A     +    +S  T IL+  ++   Y + GG  AVVWTDV+Q  
Sbjct: 123 FLLFVIARLGGLLYAAALVLSVLTGISTNTAILMVGVVSIIYTVAGGITAVVWTDVLQFG 182

Query: 188 AMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAI------VFAIG 241
            +F+ L   I   +  V  GG     +I    +  KL  F      A+I      + A G
Sbjct: 183 MIFVGLGAGIWAAVTAVP-GGFGELWRIAG--ENGKLVVFNFDWDPASIRSLPTALIAYG 239

Query: 242 YASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFIS------GIWTTIVLWGAFFAGFLGF 295
             ++ V    Q   V RY+S  D +  R+  IF+       G+  T++L G     F   
Sbjct: 240 ILAFAVAGTNQ-QSVQRYVSCADEQSARK-AIFLGWFSGVLGVGATLLL-GVLLFSFYQL 296

Query: 296 ALVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
                G+IK   P+ I+    ++ +P   +GF++A I +A MS+ DS L   ++ +  D 
Sbjct: 297 QGGLPGNIK---PDEILSYFIVNQVPPGASGFLVAAIFAAAMSSIDSALHSLATCMTVDF 353

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
           Y + +  +  + + V +++ ++    +VA++ AI        ++        +  GP+L 
Sbjct: 354 YDRYINIQASEMRSVRVAQGLIIVWGVVAIFSAIYAASTGQDLLEFLVSYTTMFLGPLLG 413

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILE--AKIYGWAFNP 453
           + L    +      +G  YG ++ V+L   A   GW   P
Sbjct: 414 IFLMGV-LFPRINALGAFYGTVAAVLLVIIASNAGWLTFP 452


>pir||E83468 probable sodium:solute symport protein PA1418 [imported] -
           Pseudomonas aeruginosa (strain PAO1)
           >gi|9947366|gb|AAG04807.1|AE004571_6 (AE004571) probable
           sodium:solute symport protein [Pseudomonas aeruginosa]
           Length = 463
           
 Score =  106 bits (263), Expect = 5e-22
 Identities = 121/454 (26%), Positives = 192/454 (41%), Gaps = 46/454 (10%)

Query: 6   LFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVH------VLAATLSDKASDFSGWLM 59
           +F  LIY   +  +GW+  +  KT D Y V GR +        +AAT+   AS   G + 
Sbjct: 5   IFVVLIYAAGMIALGWYGMRRAKTRDDYLVAGRNLGPGFYLGTMAATVLGGASTI-GTVR 63

Query: 60  LGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNT 119
           LGY       G+  FW       G +   L +   L     K +  T+   LE R     
Sbjct: 64  LGYVH-----GISGFWLCGAIGLGIVGLSLFLAKPLL----KLKIYTVTQVLERRYNPAA 114

Query: 120 KLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFA 179
              R  SA I+LV+     A    A G      F +     ILI   ++  Y   GG ++
Sbjct: 115 ---RHASALIMLVYALMIGATSTIAIGTVMQVLFGLPFWVSILIGGGVVVLYSTIGGMWS 171

Query: 180 VVWTDVVQAMFMLLTLI--IMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIV 237
           +  TD+VQ + M + L+  +MP L++ + GG D    ++A + P     F  A GW  IV
Sbjct: 172 LTLTDIVQFLIMTVGLVFLLMP-LSINDAGGWDA---LVAKL-PASYFDFT-AIGWDTIV 225

Query: 238 --FAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGF 295
             F I +    +G      I  R  +       +  G   +GI+  +        G  G 
Sbjct: 226 TYFLIYFFGIFIGQ----DIWQRVFTARSETVAKVAGS-AAGIYCVLY-------GMAGA 273

Query: 296 ALVASGSIKVEDPERIVPAMAI---HFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIA 352
            +  +  + + D E +  A A    H LP  + G VIA  ++A+MSTA + LL AS+ + 
Sbjct: 274 LIGMAAKVLLPDLENVNNAFASVVEHSLPNGIRGLVIAAALAALMSTASAGLLAASTTVT 333

Query: 353 RDIYHKV-LGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFG 411
           +D+  ++  G+       V+ +RI    + LV +  A+    VI   +  A+  L  G  
Sbjct: 334 QDLLPRLRRGRGQSDNGDVHENRIATLLLGLVVLGIALVVSDVI-SALTVAYNLLVGGML 392

Query: 412 PILTLSLWWKRVTKEAGIVGMAYGLISEVILEAK 445
             L  +++WKR T    I  M  G ++ ++   K
Sbjct: 393 IPLIGAIYWKRATTAGAITSMTLGFLTVLVFMIK 426


>pir||B69833 metabolite permease homolog yhjB - Bacillus subtilis
           >gi|2226174|emb|CAA74464.1| (Y14081) hypothetical
           protein [Bacillus subtilis] >gi|2633381|emb|CAB12885.1|
           (Z99109) similar to metabolite permease [Bacillus
           subtilis]
           Length = 489
           
 Score =  105 bits (260), Expect = 1e-21
 Identities = 111/498 (22%), Positives = 215/498 (42%), Gaps = 37/498 (7%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTE-DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYP 63
           I+FG L+  +   ++G  A K      +Q+ VGGR    +   L      ++ +  LG  
Sbjct: 7   IIFGVLLLSI---FLGIRAQKGKDMNLEQWTVGGRGFGTVFVFLLMAGEIYTTFTFLGGS 63

Query: 64  GSAFKAGLGAFWA-GIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLI 122
           G A+  G  AF+    GCL   L+ +LL  P +  YA + + ++  D+     K N+ L+
Sbjct: 64  GWAYGKGGPAFYIIAYGCLAYILSYWLL--PAVWTYAKQHKLMSQSDFFTK--KYNSPLL 119

Query: 123 RILSAAIILVFMTAYVAAQFAAGGKTFAQAF--NVSVTTGILITVIILTAYVITGGFFAV 180
            IL + + +  +  Y+  Q    G   ++     ++ T  I I  + +T YV+  G    
Sbjct: 120 GILVSLVGIAALIPYLVLQLKGLGLIVSETSYGKITPTAAIWIGAVSITVYVMVSGIHGS 179

Query: 181 VWTDVVQAMFMLLTLIIMPI-LALVEIGGLDRATQIIASVDPN--KLHPFGGATGW---A 234
            W  VV+ + +L+ ++ + + L +   GG     Q I +  P    L   G +  W    
Sbjct: 180 AWISVVKDIMILVVVLFLGVYLPIHYYGGFQDMFQQIETAKPGFLTLPESGQSVAWFSST 239

Query: 235 AIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLG 294
            ++ A+G+  W       PH  +   S E+P+  R+  I I  ++  ++L    F  F+G
Sbjct: 240 VLLTALGFYMW-------PHTFSASYSAENPKVFRKNAI-IMPLYQLVLL----FVLFVG 287

Query: 295 FALVAS-GSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIAR 353
           FA +     +   D +  +  +++     W  G + A  +   +      L+ AS+  A+
Sbjct: 288 FAAILQVPDLNGADGDLSLLRLSLQAFDPWFVGIIGAAGLLTALVPGSMILMSASTLFAK 347

Query: 354 DIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPI 413
           ++Y KV+     ++Q+  +++ +V  +AL++++F   G   I  ++   +  +   F  +
Sbjct: 348 NVY-KVIAPRTTEQQVSALAKFLVPVIALISVYFTFKGGNTIVTLLLMGYSLVTQLFPAL 406

Query: 414 LTLSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFF 473
           L   L    VTK+    G+  G      + A  Y           F  L Q    + V  
Sbjct: 407 LFSLLKHNMVTKQGAFAGIIAG------VGAVTYITMTETTIGTLFPALPQAAKDLNVGI 460

Query: 474 INFFVTLFIIIIVSLLTK 491
           +   + + +++ VSL+T+
Sbjct: 461 VALLLNITVMMAVSLMTR 478


>pir||H75513 probable sodium/proline symporter DR0477 [similarity] - Deinococcus
           radiodurans (strain R1)
           >gi|6458165|gb|AAF10057.1|AE001907_3 (AE001907)
           sodium:solute symporter protein [Deinococcus
           radiodurans]
           Length = 528
           
 Score =  105 bits (260), Expect = 1e-21
 Identities = 105/458 (22%), Positives = 188/458 (40%), Gaps = 33/458 (7%)

Query: 6   LFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65
           L   LI L+ L    W +++ T   D Y  GG K+      ++      S    LG  G 
Sbjct: 4   LLAALIVLITLGVTFWASSRNTSAGDFYVAGG-KISATQNGIAIAGDYMSAASFLGITGL 62

Query: 66  AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRIL 125
               G   F   +G     L    ++   LR   GK+   TL D L  RLKD    +R  
Sbjct: 63  IALNGYDGFMYSVGWFIAYLTVLFIVAEPLR-NLGKY---TLADMLVYRLKDQR--VRFY 116

Query: 126 SAAIILVFMTAYVAAQFAAGGKTFAQAFN--VSVTTGILITVIILTAYVITGGFFAVVWT 183
           +A   +   T Y+ AQ    G   +      +  T  I +  +++  YV+ GG  A  W 
Sbjct: 117 AAFSTITVSTFYMIAQVVGAGSLISLLSGGLLKPTLAIPLVGLLMIVYVVVGGMLATTWV 176

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNK---LHP---FGGATGWAAIV 237
            +++AM ++   I+M +L L    G   +  + A+ D N    L P   +       ++ 
Sbjct: 177 QIIKAMLLMFATIVMSVLILARF-GFSFSDLLGAATDKNGAAFLEPGLKYKNPLDLISLC 235

Query: 238 FAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFAL 297
            A+     ++G  G PHI+ R+ +V   +  R+  +   G+     +  A   G     L
Sbjct: 236 LAL-----VLGTAGLPHILVRFFTVPTAQDARKSVVVAMGLIGAFYIMTALM-GNAANVL 289

Query: 298 VASGSIKVEDPERIVPAMAIHFLPGWVAG---------FVIAGIISAVMSTADSQLLVAS 348
           V   +I   +P   + A  +    G  AG         FV A   + +++      + AS
Sbjct: 290 VGKDTIVAANPAGNMAAPLLAQALGGGAGTLGGEFGLAFVTAVAFATILAVVAGLTISAS 349

Query: 349 SAIARDIYHKVL-GQELGKKQMVNISRIVVAAVALVAMWFAITG-PKVIYQMVATAWGGL 406
           ++   DIY+ V+ G +  +++   ++R+   AV L+++   +    + +  +VA A+   
Sbjct: 350 TSFTHDIYNGVMKGGKANEQEQFKVARMATVAVGLLSIVLGLLAKDQNVAFLVALAFAIA 409

Query: 407 AVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVILEA 444
           A    P++  +L+W+       + G+  GL   ++L A
Sbjct: 410 ASANLPVILYTLFWRGFNANGAVWGIVGGLAVTLVLIA 447


>gb|AAF54633.1| (AE003691) CG6723 gene product [Drosophila melanogaster]
           Length = 587
           
 Score =  105 bits (259), Expect = 2e-21
 Identities = 120/458 (26%), Positives = 193/458 (41%), Gaps = 55/458 (12%)

Query: 9   FLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFK 68
           FL+ + I  Y G+  NK + +ED Y +GGRK+ V+    S  AS  SG  +LG P   + 
Sbjct: 26  FLLCIGIGIYFGFM-NK-SVSEDDYMLGGRKMLVIPIAFSLVASFVSGITLLGLPTEVYS 83

Query: 69  AGLGAFWA-----GIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIR 123
            G+   +      G+G + G    YL +   L I        +  +YLE R     + +R
Sbjct: 84  YGIQYLYVSCGVIGMGVVMGVF--YLPVFHDLNI-------TSTYEYLEVRFD---RRLR 131

Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
           +  + +  +   AY+          F Q   + V T   I  II   Y   GG  AVVWT
Sbjct: 132 LYGSVMFAIMNVAYLPIVIYVPALAFNQVTGIGVHTITPIVCIICVFYTSLGGLKAVVWT 191

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGL----------DRATQIIASVDPNKLHPFGGATGW 233
           DVVQA+ ML  L ++ I    +IGG           DR      S+DP   H F     W
Sbjct: 192 DVVQAISMLGALCLVAIKGTRDIGGAGVVLERAWSSDRLEAPDLSIDPTVRHTF-----W 246

Query: 234 AAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRP-GIFISGIWTTIVLWG----AF 288
              +F  G   W        +++ RY+S+      R+   IF  G+   + L G      
Sbjct: 247 C--LFFGGIVYWTQTNAVSQNMIQRYLSLPSLGDARKALCIFCVGVLILMALCGYNGLLI 304

Query: 289 FAGFLGFALVASGSIKVEDPERIVPAMAIHF---LPGWVAGFVIAGIISAVMSTADSQLL 345
           +A +     + +   K  D  +++P   +     LPG + G  IAG+ SA +S+  + L 
Sbjct: 305 YATYQNCDPLTTKLAKARD--QLLPLFVMKTLGELPG-MTGLFIAGVFSAALSSLSTCLN 361

Query: 346 VASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVAL--VAMWFAITGPKVIYQMVATAW 403
             S+ +  D     + + L    +  I R+VV  V +  V + + +     + Q+  +  
Sbjct: 362 SMSAVVLEDFVKPYVKKPLSSSAINWIMRLVVVGVGVLCVCLVYVVEHMGTVLQLTMSL- 420

Query: 404 GGLAVGFGP---ILTLSLWWKRVTKEAGIVGMAYGLIS 438
              A+  GP   I T+ L+   +   + +VG   G+I+
Sbjct: 421 --EAITNGPLFGIFTIGLFLPWINGNSALVGGVMGVIA 456


>emb|CAB59438.1| (AL132644) putative transmembrane transport protein [Streptomyces
           coelicolor A3(2)]
           Length = 544
           
 Score =  104 bits (258), Expect = 2e-21
 Identities = 112/458 (24%), Positives = 194/458 (41%), Gaps = 39/458 (8%)

Query: 9   FLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFK 68
           F ++++    I  WA + TK    ++ GGR+       L+      S    LG  G+   
Sbjct: 28  FAVFVLATLGITVWAGRQTKDAADFYAGGRQFSAFQNGLAVSGDYMSAASFLGIAGAIAL 87

Query: 69  AGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAA 128
            G   F   IG L   L   LL+   LR  +G++   T+ D L  R++   + +R  +  
Sbjct: 88  FGYDGFLYSIGFLVAWLVALLLVAEPLR-NSGRY---TMGDVLAYRMRQ--RPVRTAAGT 141

Query: 129 IILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITV----IILTAYVITGGFFAVVWTD 184
             +V    Y+ AQ A  G   +    ++   G ++ V    +++  YV  GG     W  
Sbjct: 142 STIVVSIFYLLAQMAGAGILVSLLLGITSDAGKILIVALVGVLMIVYVTIGGMKGTTWVQ 201

Query: 185 VVQAMFMLLTLIIMPILALVEIG---------GLDRATQIIASVDPNKLHPFGGATGWAA 235
           +V+A+ ++   I++  L L++             + +    A ++P   +   GA+G   
Sbjct: 202 MVKAVLLIGGTILITFLVLLKFDFNISDLLGKAAENSGAGSAFLEPGLQY---GASGTTK 258

Query: 236 IVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGF 295
           + F     + ++G  G PHI+ R+ +V + +  R+   +  GI     L      GF   
Sbjct: 259 LDFISLGIALVLGTAGLPHILIRFYTVPNAKAARKSVNWAIGIIGAFYLM-TIALGFGAA 317

Query: 296 ALVASGSIKVEDP--ERIVPAMAIHFLPGWVA---GFVIAGIISAV-----MSTADSQLL 345
           ALV    I   +P      P +A+H   G V    G ++   ISAV     ++      L
Sbjct: 318 ALVGKDEIIASNPSGNTAAPLLALHV--GGVDSTWGAILLATISAVAFATILAVVAGLTL 375

Query: 346 VASSAIARDIYHKVL--GQELGKKQMVNISRIVVAAVALVAMWF-AITGPKVIYQMVATA 402
            +SS+ A DIY  V+  GQ   K++M   +R     + +V++   A+     +  +VA A
Sbjct: 376 ASSSSFAHDIYANVIRKGQATEKEEM-RAARWATVFIGIVSIALGALARDLNVAGLVALA 434

Query: 403 WGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEV 440
           +   A    P +  SL+WKR T +  +  +  GLI  V
Sbjct: 435 FAVAASANLPTILYSLFWKRFTTQGALWSIYGGLIVAV 472


>pir||T03475 transmembrane protein - Rhodobacter capsulatus
           >gi|3128276|gb|AAC16128.1| (AF010496) transmembrane
           protein DhlC homolog [Rhodobacter capsulatus]
           Length = 578
           
 Score =  104 bits (257), Expect = 3e-21
 Identities = 109/467 (23%), Positives = 187/467 (39%), Gaps = 39/467 (8%)

Query: 6   LFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65
           +FGF  ++V   +I  WA   TK+   ++  G  +      L+      S    LG   +
Sbjct: 45  MFGF--FVVATLFITKWAAGRTKSAADFYTAGGGITGFQNGLAIAGDYMSAASFLGISAA 102

Query: 66  AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRIL 125
               G       IG L G      L+  RLR   GKF    +  +  A+       +R+ 
Sbjct: 103 VMLQGYDGLIYSIGFLVGWPILTFLMAERLR-NLGKFTFADVAAFPFAQTP-----VRVF 156

Query: 126 SAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDV 185
           +A   LV +  Y+ AQ    G+     F +     +++  I++  YV+ GG  A  W  +
Sbjct: 157 AAMSTLVVVAFYLIAQMVGAGQLIKLLFGLEYLYAVIVVGILMMVYVLFGGMTATTWVQI 216

Query: 186 VQAMFMLLTLIIMPILALVEIG-----------GLDRATQIIASVDPNK-----LHPFGG 229
           ++A  +L     M ++ +V  G            +     + A   P +     +   G 
Sbjct: 217 IKACLLLGGASFMALMVMVHYGFSLESLFADSVKVKTDLALAAGKTPEEAAAAGISIMGP 276

Query: 230 ATGWAAIVFAIGYASWIV-GYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAF 288
            T     + AI +   ++ G  G PHI+ R+ +V   ++ R+  +  + +W        F
Sbjct: 277 GTFVKDPISAISFGMALMFGTAGLPHILMRFFTVPSAKEARK-SVMWATVWIGYFYMLTF 335

Query: 289 FAGF--LGFALVASGSIKVEDPERIVPA----MAIHFLPGWVAGFVIAGIISAV-----M 337
             GF  + + L   G +  +    +       MA   L   V G +  G ISAV     +
Sbjct: 336 IIGFGAIVYVLTNPGLVSYDAKGALTLVGGNNMAAIHLAQAVGGNIFLGFISAVAFATIL 395

Query: 338 STADSQLLVASSAIARDIYHKVLGQ-ELGKKQMVNISRIVVAAVALVAMWFAITGPKV-I 395
           +      L  +SA++ D+Y  V    +      + +SRI    + +VA+   +   K  I
Sbjct: 396 AVVAGLTLSGASAVSHDLYSTVFKNGKADSASELRVSRITTICLGIVAVVLGLAFEKQNI 455

Query: 396 YQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVIL 442
             MV+ A+   A    P+L +SL WK +T    ++G + GLIS V L
Sbjct: 456 AFMVSLAFAIAASANFPVLFMSLLWKGMTTRGAVIGGSLGLISSVAL 502


>dbj|BAB05941.1| (AP001514) Na+/myo-inositol cotransporter [Bacillus halodurans]
           Length = 580
           
 Score =  101 bits (249), Expect = 2e-20
 Identities = 90/409 (22%), Positives = 184/409 (44%), Gaps = 31/409 (7%)

Query: 5   ILFGFLIYLVILAYIGWWANKYT--KTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGY 62
           IL  FL+Y + + +  W+  + T   + D YF+GGR +  +    S   ++ S   ++G 
Sbjct: 5   ILASFLMYSIFVMWFSWYKTRGTDLSSSDGYFLGGRSLTGIVIASSLILTNLSTEQVVGL 64

Query: 63  PGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLI 122
            G AF   +      +      +    +  PR      K    T+PD+LE R    T+  
Sbjct: 65  NGQAFGESMVVMAWEVTAPIALILMAFVFLPRYL----KLGITTIPDFLEQRFDLRTR-- 118

Query: 123 RILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILT----------AYV 172
           +I+S   +L + T ++     +G       F++S    I   +I+L            YV
Sbjct: 119 QIVSVLFLLGYATVFLPTVLYSGALVIDSIFSLSSVMDISPFMIVLCISIAIGIISCGYV 178

Query: 173 ITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQI--IASVDPNKLHPFGG- 229
           I GG  A   +D +  + +++  +++PILAL  +G  D A+ +  + S +P KL+  G  
Sbjct: 179 ILGGLKACAMSDTINGIGLIIGGLLIPILALFVLGRGDFASGVGELVSANPTKLNAIGND 238

Query: 230 --ATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGA 287
             +  WA ++  + + +       Q  I+ R ++ ++  + ++ G+  +G++    ++GA
Sbjct: 239 QASVPWAVLLTGLLFNNLFYWCTNQS-IIQRTLAAKNLAEGQK-GVLFAGMFK---IFGA 293

Query: 288 FFAGFLGFALVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVA 347
            F    G          + + +   P++ I  +P  ++GF+ A +  A++S+ ++ L  +
Sbjct: 294 AFLVLPGIIAYLLYGDVLANADMAYPSLVIDVMPVALSGFLAAVLFGAILSSFNNVLNSS 353

Query: 348 SSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIY 396
            +    DIY  +      + ++V   RI  A +A+ A+   +  P ++Y
Sbjct: 354 ITLFTLDIYKPIFKPNAKEPELVKAGRIFAACLAITAV---VIAPFILY 399


>pir||C69903 proline permease homolog yodF - Bacillus subtilis
           >gi|2415386|gb|AAB72054.1| (AF015775) permease [Bacillus
           subtilis] >gi|2634350|emb|CAB13849.1| (Z99114) similar
           to proline permease [Bacillus subtilis]
           Length = 496
           
 Score =  100 bits (247), Expect = 4e-20
 Identities = 106/443 (23%), Positives = 193/443 (42%), Gaps = 39/443 (8%)

Query: 11  IYLVILAYIGWWA--NKYTKTE-DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAF 67
           I ++ +  IG+ A  +K ++T  +++ VGGR+   L       A  ++ +  LG   +AF
Sbjct: 13  IIVLTVVCIGFLAGRDKSSRTSVEEWSVGGRRFGGLLVWFLVGADLYTAYTFLGLTSTAF 72

Query: 68  KAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSA 127
             G  AF+A    +      Y  + P+L   A   +  TL DY  AR + N+KL+  L A
Sbjct: 73  TGGSVAFFAIPYSVLAYFIAYFFL-PKLWKVAKIHKLTTLADY--ARERFNSKLLASLVA 129

Query: 128 AIILVFMTAYVAAQFAAGGKTFAQAFN--VSVTTGILITVIILTAYVITGGFFAVVWTDV 185
            + ++ +  Y+  Q +    T   A    ++V   ++I+ I++  Y    G     +T +
Sbjct: 130 IVGVLMLIPYICLQLSGIQDTLQVAGTGYINVKFVVIISFILVALYTFFSGIKGPTYTAI 189

Query: 186 VQAMFMLLTLIIMPI-LALVEIGGLDRATQIIASVDPNKLH-PFGGATG--W---AAIVF 238
           ++ + + + ++ M + L L+   G       +    P  L  P  G  G  W   A+IV 
Sbjct: 190 IKDILVWVIMLFMVVSLPLIHFNGWTPMIDTLVKEAPQMLTIPSEGPKGIPWFITASIVS 249

Query: 239 AIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALV 298
           A+    W        H  T   + +    +R+  +F+      IVL    F GF+ F ++
Sbjct: 250 ALALFMWA-------HAATGVFTAKSADAVRKNSMFLP--LYNIVLILVIFLGFIAFLVL 300

Query: 299 ASGSIKVEDPERIVPAMAIHFL-----PGWVAGFVIAGIISAVMSTADSQLLVASSAIAR 353
                    PE   P +A+  L      G   GF  A I  A +       + AS+  A 
Sbjct: 301 ---------PEDTNPRLALLHLIQTSYGGVAQGFAYATIALASLIPCSIMAIGASNLFAN 351

Query: 354 DIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPI 413
           ++Y  ++   + + ++  ++R +V  V  +A+ F +  P  +  +      G+   F P 
Sbjct: 352 NLYRDLIHPNVSQSKLTLVTRSMVFVVIGLALLFGMLFPTALVTLQLLGVSGMVQIF-PA 410

Query: 414 LTLSLWWKRVTKEAGIVGMAYGL 436
           + +SL+WK  TKEA ++G+  GL
Sbjct: 411 IAVSLFWKNQTKEATVIGLLAGL 433


>emb|CAC17810.1| (AJ276242) sodium iodide symporter [Sus scrofa]
           Length = 643
           
 Score = 99.5 bits (244), Expect = 9e-20
 Identities = 114/457 (24%), Positives = 190/457 (40%), Gaps = 52/457 (11%)

Query: 9   FLIYLVILAYIGWW---ANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65
           F + L++   IG W   A    ++ + +F GGR++  +   LS  AS  S   +LG P  
Sbjct: 20  FALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLTAVPVGLSLSASFMSAVQVLGVPAE 79

Query: 66  AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRIL 125
           A++ GL   W  +G L  +L   LL  P       +    +   YLE R    ++ +R+ 
Sbjct: 80  AYRYGLKFLWMCLGQLLNSLLTALLFLPVFY----RLGLTSTYQYLELRF---SRAVRLC 132

Query: 126 SAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDV 185
                LV    Y      A      Q   + +   +L T II T Y   GG  AV+WTDV
Sbjct: 133 GTLQYLVATMLYTGVVIYAPALILNQVTGLDIWASLLSTGIICTFYTTVGGMKAVIWTDV 192

Query: 186 VQAMFMLLTLIIMPILALVEIGGLDRATQIIAS----------VDPNKLHPFGGATGWAA 235
            Q + ML    ++     V +GG  R  ++  +          +DP + + F     W  
Sbjct: 193 FQVLVMLTGFWVVLARGTVLVGGPGRVLELAKNHSRINLMDFDLDPRRRYTF-----WTF 247

Query: 236 IVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGF 295
           +V   G   W+  Y      V RY++     K  +  + I+ +   +++  A   G + F
Sbjct: 248 VVG--GTLVWLSMYGVNQAQVQRYVACR-TEKQAKLALLINQVGLFLIVSSAAACGIVMF 304

Query: 296 AL------VASGSIKVEDPERIVPAMAIHF---LPGWVAGFVIAGIISAVMSTADSQLLV 346
           AL      + +G I    P++ +P + +     LPG V G  +A   S  +STA + +  
Sbjct: 305 ALYVDCDPLLAGHISA--PDQYMPLLVLDIFEDLPG-VPGLFLACAYSGTLSTASTSINA 361

Query: 347 ASSAIARDIYHKVLGQELGKKQMVNISR----IVVAAVALVAMWFAITGPKVIYQMVATA 402
            ++    D+    L   L  +++V IS+    I  +A   VA   ++ G  V+ Q   T 
Sbjct: 362 MAAVTVEDLIKPRL-PNLAPRRLVIISKGLSLIYGSACLTVAALSSLLGGGVL-QGSFTV 419

Query: 403 WGGLAVGFGPIL---TLSLWWKRVTKEAGIVGMAYGL 436
            G ++   GP+L    L ++         + G+A GL
Sbjct: 420 MGVIS---GPLLGAFVLGMFLPSCNTSGVLSGLAAGL 453


>emb|CAC17816.1| (AJ276292) sodium iodide symporter [Sus scrofa]
           Length = 636
           
 Score = 99.5 bits (244), Expect = 9e-20
 Identities = 114/457 (24%), Positives = 190/457 (40%), Gaps = 52/457 (11%)

Query: 9   FLIYLVILAYIGWW---ANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65
           F + L++   IG W   A    ++ + +F GGR++  +   LS  AS  S   +LG P  
Sbjct: 20  FALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLTAVPVGLSLSASFMSAVQVLGVPAE 79

Query: 66  AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRIL 125
           A++ GL   W  +G L  +L   LL  P       +    +   YLE R    ++ +R+ 
Sbjct: 80  AYRYGLKFLWMCLGQLLNSLLTALLFLPVFY----RLGLTSTYQYLELRF---SRAVRLC 132

Query: 126 SAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDV 185
                LV    Y      A      Q   + +   +L T II T Y   GG  AV+WTDV
Sbjct: 133 GTLQYLVATMLYTGVVIYAPALILNQVTGLDIWASLLSTGIICTFYTTVGGMKAVIWTDV 192

Query: 186 VQAMFMLLTLIIMPILALVEIGGLDRATQIIAS----------VDPNKLHPFGGATGWAA 235
            Q + ML    ++     V +GG  R  ++  +          +DP + + F     W  
Sbjct: 193 FQVLVMLTGFWVVLARGTVLVGGPGRVLELAKNHSRINLMDFDLDPRRRYTF-----WTF 247

Query: 236 IVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGF 295
           +V   G   W+  Y      V RY++     K  +  + I+ +   +++  A   G + F
Sbjct: 248 VVG--GTLVWLSMYGVNQAQVQRYVACR-TEKQAKLALLINQVGLFLIVSSAAACGIVMF 304

Query: 296 AL------VASGSIKVEDPERIVPAMAIHF---LPGWVAGFVIAGIISAVMSTADSQLLV 346
           AL      + +G I    P++ +P + +     LPG V G  +A   S  +STA + +  
Sbjct: 305 ALYVDCDPLLAGHISA--PDQYMPLLVLDIFEDLPG-VPGLFLACAYSGTLSTASTSINA 361

Query: 347 ASSAIARDIYHKVLGQELGKKQMVNISR----IVVAAVALVAMWFAITGPKVIYQMVATA 402
            ++    D+    L   L  +++V IS+    I  +A   VA   ++ G  V+ Q   T 
Sbjct: 362 MAAVTVEDLIKPRL-PNLAPRRLVIISKGLSLIYGSACLTVAALSSLLGGGVL-QGSFTV 419

Query: 403 WGGLAVGFGPIL---TLSLWWKRVTKEAGIVGMAYGL 436
            G ++   GP+L    L ++         + G+A GL
Sbjct: 420 MGVIS---GPLLGAFVLGMFLPSCNTSGVLSGLAAGL 453


>gb|AAB81169.1| (AF006665) YolC [Bacillus subtilis]
           Length = 496
           
 Score = 99.1 bits (243), Expect = 1e-19
 Identities = 105/443 (23%), Positives = 192/443 (42%), Gaps = 39/443 (8%)

Query: 11  IYLVILAYIGWWA--NKYTKTE-DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAF 67
           I ++ +  IG+ A  +K ++T  +++ VGGR+   L       A  ++ +  LG   + F
Sbjct: 13  IIVLTVVCIGFLAGRDKSSRTSVEEWSVGGRRFGGLLVWFLVGADLYTAYTFLGLTSTTF 72

Query: 68  KAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSA 127
             G  AF+A    +      Y  + P+L   A   +  TL DY  AR + N+KL+  L A
Sbjct: 73  TGGSVAFFAIPYSVLAYFIAYFFL-PKLWKVAKIHKLTTLADY--ARERFNSKLLASLVA 129

Query: 128 AIILVFMTAYVAAQFAAGGKTFAQAFN--VSVTTGILITVIILTAYVITGGFFAVVWTDV 185
            + ++ +  Y+  Q +    T   A    ++V   ++I+ I++  Y    G     +T +
Sbjct: 130 IVGVLMLIPYICLQLSGIQDTLQVAGTGYINVKFVVIISFILVALYTFFSGIKGPTYTAI 189

Query: 186 VQAMFMLLTLIIMPI-LALVEIGGLDRATQIIASVDPNKLH-PFGGATG--W---AAIVF 238
           ++ + + + ++ M + L L+   G       +    P  L  P  G  G  W   A+IV 
Sbjct: 190 IKDILVWVIMLFMVVSLPLIHFNGWTPMIDTLVKEAPQMLTIPSEGPKGIPWFITASIVS 249

Query: 239 AIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALV 298
           A+    W        H  T   + +    +R+  +F+      IVL    F GF+ F ++
Sbjct: 250 ALALFMWA-------HAATGVFTAKSADAVRKNSMFLP--LYNIVLILVIFLGFIAFLVL 300

Query: 299 ASGSIKVEDPERIVPAMAIHFL-----PGWVAGFVIAGIISAVMSTADSQLLVASSAIAR 353
                    PE   P +A+  L      G   GF  A I  A +       + AS+  A 
Sbjct: 301 ---------PEDTNPRLALLHLIQTSYGGVAQGFAYATIALASLIPCSIMAIGASNLFAN 351

Query: 354 DIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPI 413
           ++Y  ++   + + ++  ++R +V  V  +A+ F +  P  +  +      G+   F P 
Sbjct: 352 NLYRDLIHPNVSQSKLTLVTRSMVFVVIGLALLFGMLFPTALVTLQLLGVSGMVQIF-PA 410

Query: 414 LTLSLWWKRVTKEAGIVGMAYGL 436
           + +SL+WK  TKEA ++G+  GL
Sbjct: 411 IAVSLFWKNQTKEATVIGLLAGL 433


>pir||T35201 probable transmembrane transport - Streptomyces coelicolor
           >gi|3036892|emb|CAA18525.1| (AL022374) SC5B8.17,
           probable transmembrane transport protein, len: 530 aa;
           member of the sodium:solute symporter family, similar to
           many e.g. YJCG_ECOLI P32705 hypothetical protein , (549
           aa), fasta scores; opt: 935 z-score: 1534.8 E(): 0,
           43.6% ident>
           Length = 530
           
 Score = 99.1 bits (243), Expect = 1e-19
 Identities = 110/456 (24%), Positives = 187/456 (40%), Gaps = 41/456 (8%)

Query: 14  VILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGA 73
           V L    W   +   + ++++ GGR    +    +      S    LG  G     G   
Sbjct: 19  VTLGITTWVGRRRQGSAEEFYAGGRLFSPMENGFAISGDYMSAASFLGISGLIALNGYDG 78

Query: 74  FWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAAIILVF 133
               +G L   L    L+   +R   G+F   TL D + AR+++    +RI +    +  
Sbjct: 79  MLYSVGFLVAWLVVLFLVAELVR-NCGRF---TLADVVAARMRERP--VRIAAGTSSVTV 132

Query: 134 MTAYVAAQFAAGGKTFAQAFNVSVTTGILITVI----ILTAYVITGGFFAVVWTDVVQAM 189
              Y+ AQ    G   A     +       TVI    ++  YV  GG  A  W  +V+A+
Sbjct: 133 SVLYLVAQMVGAGSLVALLLGGTSEAARTWTVIGVGALMVIYVSLGGMRATTWIQIVKAV 192

Query: 190 FMLLTLIIMPILALVEI-GGLDRATQIIASVDPNK---LHP---FGGATGWAAIVFAIGY 242
            +L   + +  L LV   G +DR  +  A    +    L P   +GG   W A    I  
Sbjct: 193 LLLGGTVALTALVLVRFHGDVDRLLRTAAERSGHGEAFLAPGLAYGG--DWVARFDFISL 250

Query: 243 A-SWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFF-----AGFLGFA 296
             + ++G  G PHI++R+ +V   R  RR     S +W +I L G F+      GF   A
Sbjct: 251 GLALVLGTAGLPHILSRFYTVPTARAARR-----SVVW-SIGLIGGFYLMTIVLGFGAAA 304

Query: 297 LVASGSIKVEDP--ERIVPAMAI------HFLPGWVAGFVIAGIISAVMSTADSQLLVAS 348
           LV   +++  +      VP +A+      H   G V   V+A +  A +    + + +AS
Sbjct: 305 LVGPNAVRASNAAGNTAVPLLALDLGGGAHSTGGTVLFAVVAAVAFATILAVVAGITLAS 364

Query: 349 SA-IARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKV-IYQMVATAWGGL 406
           SA +A D+Y  +  +    +  V ++R+    +  VA+   +    + +  +V  A+   
Sbjct: 365 SASVAHDLYASLRRRHSKPRSEVAVARVAAVGIGAVAIGLGLLARDLNVAFLVGLAFAVA 424

Query: 407 AVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVIL 442
           A    P+L  SL+W+  T    +  +  GL+  V+L
Sbjct: 425 ASANLPVLLYSLFWRGFTTRGAVWAVYGGLVPSVVL 460


>gb|AAG01741.1|AF251267_1 (AF251267) low affinity sodium-glucose cotransporter [Mus musculus]
           Length = 656
           
 Score = 95.2 bits (233), Expect = 2e-18
 Identities = 118/536 (22%), Positives = 224/536 (41%), Gaps = 63/536 (11%)

Query: 10  LIYLVILAYIGWWANKYTK--TEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAF 67
           +IY V++  +G WA   T   T   +F+ GR +       S  AS+      +G  G+  
Sbjct: 33  VIYFVVVMAVGVWAMLKTNRSTVGGFFLAGRSMTWWPMGASLFASNIGSGHFVGLAGTGA 92

Query: 68  KAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSA 127
            +G+ A  A     F  L     I   + I AG    +T+P+YL+ R     +L   LS 
Sbjct: 93  ASGI-AVTAFESHSFALLLVLGWIFVPIYIKAG---VMTMPEYLKKRF-GGKRLQIYLSI 147

Query: 128 AIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQ 187
             + + +   ++A   +G      A  +++   ILI + I   + ITGG  +V++TD VQ
Sbjct: 148 LFLFICVILTISADIFSGAIFIKLALGLNLYLAILILLAITAIFTITGGLASVIYTDTVQ 207

Query: 188 AMFMLLTLIIMPILALVEIGGLDRATQ----IIASV---------------DPNKLH--- 225
           A+ ML+   I+ + A VE+GG +  T+     I SV                P+  H   
Sbjct: 208 AVIMLVGSFILMVFAFVEVGGYESFTEKFMNAIPSVVEGDNLTINSRCYTPQPDSFHIFR 267

Query: 226 -PFGGATGWAAIVFAIGYAS---WIV--------------GYLGQPHIVTRYMSVEDPRK 267
            P  G   W    F +   +   W +               ++    I+  Y+ +     
Sbjct: 268 DPVTGDIPWPGTAFGMPITALWYWCINQVIVQRCLCGKNLSHVKAACILCGYLKLLPLFF 327

Query: 268 LRRPGIFISGIWTTIVLWGAFFAGFLGFALVASGSIKVEDPERIVPAMAIHFLPGWVAGF 327
           +  PG+    ++T +V      A  +    V    + V       P + +  +P  + G 
Sbjct: 328 MVMPGMISRILYTDMV------ACVVPSECVKHCGVDVGCTNYAYPMLVLKLMPPGLRGL 381

Query: 328 VIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVA-MW 386
           +++ +++++MS+  S    AS+    D+Y K+  ++  +++++   R+ V+ + + + +W
Sbjct: 382 MLSVMLASLMSSLTSVFNSASTLFTIDLYTKI-RKKASERELLIAGRLFVSVLIVTSILW 440

Query: 387 FAIT-----GPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVI 441
             I      G  V Y    +++ G  +    +  ++++ KR  ++    G+  GL+  +I
Sbjct: 441 VPIVEVSQGGQLVHYTEAISSYLGPPI--AAVFLVAVFCKRANEQGAFWGLMVGLVMGLI 498

Query: 442 LEAKIYGWAFNP-KAPGFFGTLGQWFNGVPVFFINFFVTLFIIIIVSLLTKPPEDV 496
                + +      AP     +    + +    I FFV + +I+ VS LTKP  DV
Sbjct: 499 RMIAEFSYGTGSCLAPSSCPKIICGVHYLYFAIILFFVCILVILGVSYLTKPIPDV 554


>pir||E72071 hypothetical proline permease - Chlamydophila pneumoniae  (strain
           CWL029) >gi|4376772|gb|AAD18626.1| (AE001634)
           hypothetical proline permease [Chlamydophila pneumoniae
           CWL029] >gi|8978856|dbj|BAA98692.1| (AP002546)
           hypothetical proline permease [Chlamydophila pneumoniae
           J138]
           Length = 460
           
 Score = 95.2 bits (233), Expect = 2e-18
 Identities = 111/443 (25%), Positives = 198/443 (44%), Gaps = 58/443 (13%)

Query: 1   MNFGILFGFLIYLV-ILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLM 59
           MNF +   FLI +  I  Y+G   +K  +  + YF+ GR + +    ++  A+   G ++
Sbjct: 17  MNFSLFLFFLIAIQGICLYVGRRGSKKVEDRESYFLAGRSLKIFPLMMTFIATQIGGGVL 76

Query: 60  LGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNT 119
           LG    AF  G G     +G   G +  +L +GP  R+  G    +     +    K   
Sbjct: 77  LGAAEEAFCYGYGGILYPLGVALGLI--FLGMGPGKRLAEGSLTTVVSIFEVFYGSKKLR 134

Query: 120 KLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITV---IILTAYVITGG 176
           K+  +LSA  +   + A V A      + F+     S   G  +TV   I+L +Y  TGG
Sbjct: 135 KIAFLLSAGSLFFILVAQVIAL----DRLFS-----SFPFGKYVTVAFWIVLASYTSTGG 185

Query: 177 FFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAI 236
           F  VV TDV+QA F+L+ +++  +   + +       + ++ +DP +  P    + W  +
Sbjct: 186 FRGVVRTDVIQAGFLLIAVLVCGVSVWLSV------PKSLSVLDPFQSLPCAKLSNWIFM 239

Query: 237 VFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFA 296
                    ++  L +  +V R ++   P++L+   +   G    ++L+  F   FLG +
Sbjct: 240 P--------MLFMLVEQDMVQRCVAASSPKRLQWAAV---GAGLVLLLFN-FIPLFLG-S 286

Query: 297 LVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI- 355
           L A   +K   P  ++  +A +F    +A  + A I  A++STADS +   S  IA +  
Sbjct: 287 LGAKAGLKAGCP--LIDTIA-YFCNPSLAAVMAAAIGVAILSTADSLMNAVSQLIAEEYP 343

Query: 356 -----YHK--VLGQELGKKQM----VNISRIVVAAVAL------VAMWFAITGPKVIYQM 398
                Y++  VLG  +    +     NI  +++ + +L      V + F +  PK     
Sbjct: 344 TLKAPYYRYLVLGLAVAAPLVAIGFTNIVDVLILSYSLSVCCLSVPVGFYLLAPKGRRVS 403

Query: 399 VATAWGGL---AVGFGPILTLSL 418
            A AW G+   A+G+G +  +SL
Sbjct: 404 GAAAWAGVLVGALGYGWVQIVSL 426


>gb|AAF73651.1| (AE002186) sodium:solute symporter family protein [Chlamydophila
           pneumoniae AR39]
           Length = 444
           
 Score = 95.2 bits (233), Expect = 2e-18
 Identities = 111/443 (25%), Positives = 198/443 (44%), Gaps = 58/443 (13%)

Query: 1   MNFGILFGFLIYLV-ILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLM 59
           MNF +   FLI +  I  Y+G   +K  +  + YF+ GR + +    ++  A+   G ++
Sbjct: 1   MNFSLFLFFLIAIQGICLYVGRRGSKKVEDRESYFLAGRSLKIFPLMMTFIATQIGGGVL 60

Query: 60  LGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNT 119
           LG    AF  G G     +G   G +  +L +GP  R+  G    +     +    K   
Sbjct: 61  LGAAEEAFCYGYGGILYPLGVALGLI--FLGMGPGKRLAEGSLTTVVSIFEVFYGSKKLR 118

Query: 120 KLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITV---IILTAYVITGG 176
           K+  +LSA  +   + A V A      + F+     S   G  +TV   I+L +Y  TGG
Sbjct: 119 KIAFLLSAGSLFFILVAQVIAL----DRLFS-----SFPFGKYVTVAFWIVLASYTSTGG 169

Query: 177 FFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAI 236
           F  VV TDV+QA F+L+ +++  +   + +       + ++ +DP +  P    + W  +
Sbjct: 170 FRGVVRTDVIQAGFLLIAVLVCGVSVWLSV------PKSLSVLDPFQSLPCAKLSNWIFM 223

Query: 237 VFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFA 296
                    ++  L +  +V R ++   P++L+   +   G    ++L+  F   FLG +
Sbjct: 224 P--------MLFMLVEQDMVQRCVAASSPKRLQWAAV---GAGLVLLLFN-FIPLFLG-S 270

Query: 297 LVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI- 355
           L A   +K   P  ++  +A +F    +A  + A I  A++STADS +   S  IA +  
Sbjct: 271 LGAKAGLKAGCP--LIDTIA-YFCNPSLAAVMAAAIGVAILSTADSLMNAVSQLIAEEYP 327

Query: 356 -----YHK--VLGQELGKKQM----VNISRIVVAAVAL------VAMWFAITGPKVIYQM 398
                Y++  VLG  +    +     NI  +++ + +L      V + F +  PK     
Sbjct: 328 TLKAPYYRYLVLGLAVAAPLVAIGFTNIVDVLILSYSLSVCCLSVPVGFYLLAPKGRRVS 387

Query: 399 VATAWGGL---AVGFGPILTLSL 418
            A AW G+   A+G+G +  +SL
Sbjct: 388 GAAAWAGVLVGALGYGWVQIVSL 410


>emb|CAB95932.1| (AL359989) putative sodium:solute symporter [Streptomyces
           coelicolor A3(2)]
           Length = 562
           
 Score = 93.6 bits (229), Expect = 5e-18
 Identities = 97/458 (21%), Positives = 190/458 (41%), Gaps = 35/458 (7%)

Query: 11  IYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAG 70
           IY V++  IG+ A +  +T   +F+ GR +      L+  A++     +LG   ++ + G
Sbjct: 28  IYFVVVLGIGFAARRSVRTSLDFFLSGRSLPAWVTGLAFVAANLGATEILGMAANSAQYG 87

Query: 71  L-GAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAAI 129
           +    W  IG +   +   L++ P    Y  K R++  P++L  R     K   +LS+A+
Sbjct: 88  VYTTHWYWIGAIPAMVFLGLVMMPFY--YGSKVRSV--PEFLLLRFD---KASHLLSSAL 140

Query: 130 ILVFMTAYVAAQFAAGGKTFAQAFNVSVTTG------ILITVIILTAYVITGGFFAVVWT 183
             +      AA   AG   +A A  V    G      I++    + AY+  GG  + ++ 
Sbjct: 141 FAI------AAILIAGVNLYALAIVVEALLGWPEWVAIVVAGFFVLAYITLGGLSSAIYN 194

Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATG----------W 233
           +V+Q   +L  LI + IL L ++GG D  +  ++    +      G TG          W
Sbjct: 195 EVLQFFVILAGLIPITILGLKKVGGWDGLSDSLSKSHGSDFMTAWGGTGIGSENPLGANW 254

Query: 234 AAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFL 293
             IV  +G+      +      V R +S ++    +R  + I+      +++     G +
Sbjct: 255 LTIVLGLGFVLSFGYWTTNFAEVQRALSAKNLSAAQRTPL-IAAFPKIFIVFVVMIPGLV 313

Query: 294 GFALVASGSIKVEDPE--RIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAI 351
              LV        D +    +P +    LP  V G  + G+++A M+   + +   ++  
Sbjct: 314 AAVLVPKIGTPGSDLQYNDAIPYLMQQLLPNGVLGIAVTGLLAAFMAGMAANISSFNTVF 373

Query: 352 ARDIYHKVLGQELGKKQMVNISRI--VVAAVALVAMWFAITGPKVIYQMVATAWGGLAVG 409
             DI+ K + ++      V   R+  V+  +A +   F  +    I   + T +    V 
Sbjct: 374 TTDIWQKYVVKDREDGYYVRFGRLITVIGVLASIGTAFLASSFSNIMSYLQTLFSFFNVP 433

Query: 410 FGPILTLSLWWKRVTKEAGIVGMAYGLISEVILEAKIY 447
              +  + ++WKR + ++G  G+  G  + ++    IY
Sbjct: 434 MFVVFIIGMFWKRASMKSGFWGLIAGTTAAMVNYFVIY 471


>gi|6981552 solute carrier family 5, member alpha 1 (Na+/glucose cotransporter)
           [Rattus norvegicus] >gi|1709218|sp|P53790|SL51_RAT
           SODIUM/GLUCOSE COTRANSPORTER 1 (NA(+)/GLUCOSE
           COTRANSPORTER 1) (HIGH AFFINITY SODIUM-GLUCOSE
           COTRANSPORTER) >gi|1083725|pir||A53582 Na+/glucose
           cotransporter SGLT1 - rat >gi|286259|dbj|BAA03676.1|
           (D16101) Sodium/glucose cotransporter [Rattus
           norvegicus] >gi|414572|gb|AAA19015.1| (U03120)
           sodium-glucose cotransporter 1 [Rattus norvegicus]
           Length = 665
           
 Score = 93.2 bits (228), Expect = 7e-18
 Identities = 122/538 (22%), Positives = 220/538 (40%), Gaps = 67/538 (12%)

Query: 10  LIYLVILAYIGWWANKYTK--TEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAF 67
           +IY V++  +G WA   T   T   +F+ GR +       S  AS+      +G  G+  
Sbjct: 33  VIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGA 92

Query: 68  KAGL---GAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRI 124
            AG+   G  W  +  +F  +  +L +   + I AG    +T+P+YL  R     K I+I
Sbjct: 93  AAGIAMGGFEWNAL--VFVVVLGWLFVP--IYIKAG---VVTMPEYLRKRF--GGKRIQI 143

Query: 125 -LSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
            LS   +L+++   ++A   +G      A  + +   I I + I   Y ITGG  AV++T
Sbjct: 144 YLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLAAVIYT 203

Query: 184 DVVQAMFMLLTLIIMPILALVEIGG----LDRATQIIASV--DPN-------------KL 224
           D +Q   ML+   I+   A  E+GG    +D+  + I ++  D N               
Sbjct: 204 DTLQTAIMLVGSFILTGFAFREVGGYEAFMDKYMKAIPTLVSDGNITVKEECYTPRADSF 263

Query: 225 H----PFGGATGWAAIVFAIG-YASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIW 279
           H    P  G   W  ++F +   A W   +     IV R +S ++   + + G  + G  
Sbjct: 264 HIFRDPITGDMPWPGLIFGLSILALWY--WCTDQVIVQRCLSAKNMSHV-KAGCTLCGYL 320

Query: 280 TTIVLWGAFFAGFLG-------FALVASGSIK------VEDPERIVPAMAIHFLPGWVAG 326
             + ++     G +         A V     K      V       P + +  +P  + G
Sbjct: 321 KLLPMFLMVMPGMISRILYTDKIACVLPSECKKYCGTPVGCTNIAYPTLVVELMPNGLRG 380

Query: 327 FVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMW 386
            +++ +++++MS+  S    AS+    DIY K+      K+ M+     ++  + +   W
Sbjct: 381 LMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKGASEKELMIAGRLFILVLIGISIAW 440

Query: 387 FAITGPK---VIYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGL---ISEV 440
             I        ++  + +    L      +  L+++ KRV +     G+  G    IS +
Sbjct: 441 VPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPGAFWGLILGFLIGISRM 500

Query: 441 ILE-AKIYGWAFNP-KAPGFFGTLGQWFNGVPVFFINFFVTLFIIIIVSLLTKPPEDV 496
           I E A   G    P   P     +   +  +    I F +++  ++++SLLTKP  DV
Sbjct: 501 ITEFAYGTGSCMEPSNCPKIICGVHYLYFAI----ILFAISVVTVLVISLLTKPIPDV 554


>dbj|BAA19172.1| (AB000729) Na/glucose cotransporter [Rattus norvegicus]
           Length = 665
           
 Score = 93.2 bits (228), Expect = 7e-18
 Identities = 122/538 (22%), Positives = 220/538 (40%), Gaps = 67/538 (12%)

Query: 10  LIYLVILAYIGWWANKYTK--TEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAF 67
           +IY V++  +G WA   T   T   +F+ GR +       S  AS+      +G  G+  
Sbjct: 33  VIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGA 92

Query: 68  KAGL---GAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRI 124
            AG+   G  W  +  +F  +  +L +   + I AG    +T+P+YL  R     K I+I
Sbjct: 93  AAGIAMGGFEWNAL--VFVVVLGWLFVP--IYIKAG---VVTMPEYLRKRF--GGKRIQI 143

Query: 125 -LSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183
            LS   +L+++   ++A   +G      A  + +   I I + I   Y ITGG  AV++T
Sbjct: 144 YLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLAAVIYT 203

Query: 184 DVVQAMFMLLTLIIMPILALVEIGG----LDRATQIIASV--DPN-------------KL 224
           D +Q   ML+   I+   A  E+GG    +D+  + I ++  D N               
Sbjct: 204 DTLQTAIMLVGSFILTGFAFREVGGYEAFMDKYMKAIPTLVSDGNITVKEECYTPRADSF 263

Query: 225 H----PFGGATGWAAIVFAIG-YASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIW 279
           H    P  G   W  ++F +   A W   +     IV R +S ++   + + G  + G  
Sbjct: 264 HIFRDPITGDMPWPGLIFGLSILALWY--WCTDQVIVQRCLSAKNMSHV-KAGCTLCGYL 320

Query: 280 TTIVLWGAFFAGFLG-------FALVASGSIK------VEDPERIVPAMAIHFLPGWVAG 326
             + ++     G +         A V     K      V       P + +  +P  + G
Sbjct: 321 KLLPMFLMVMPGMISRILYTDKIACVLPSECKKHCGTPVGCTNIAYPTLVVELMPNGLRG 380

Query: 327 FVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMW 386
            +++ +++++MS+  S    AS+    DIY K+      K+ M+     ++  + +   W
Sbjct: 381 LMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKGASEKELMIAGRLFILVLIGISIAW 440

Query: 387 FAITGPK---VIYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGL---ISEV 440
             I        ++  + +    L      +  L+++ KRV +     G+  G    IS +
Sbjct: 441 VPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPGAFWGLILGFLIGISRM 500

Query: 441 ILE-AKIYGWAFNP-KAPGFFGTLGQWFNGVPVFFINFFVTLFIIIIVSLLTKPPEDV 496
           I E A   G    P   P     +   +  +    I F +++  ++++SLLTKP  DV
Sbjct: 501 ITEFAYGTGSCMEPSNCPKIICGVHYLYFAI----ILFAISVVTVLVISLLTKPIPDV 554


>gi|4507035 solute carrier family 5 (sodium iodide symporter), member 5 [Homo
           sapiens] >gi|11526040|ref|XP_009295.1| solute carrier
           family 5 (sodium iodide symporter), member 5 [Homo
           sapiens] >gi|2136179|pir||JC4974 sodium iodide symporter
           - human >gi|1628579|gb|AAB17378.1| (U66088) sodium
           iodide symporter [Homo sapiens]
           >gi|3702269|gb|AAC62827.1| (AC005796) sodium iodide
           symporter [Homo sapiens]
           Length = 643
           
 Score = 92.4 bits (226), Expect = 1e-17
 Identities = 111/452 (24%), Positives = 184/452 (40%), Gaps = 54/452 (11%)

Query: 9   FLIYLVILAYIGWW---ANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65
           F + L++   IG W   A    ++ + +F GGR++  L   LS  AS  S   +LG P  
Sbjct: 20  FALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLGVPSE 79

Query: 66  AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRIL 125
           A++ GL   W  +G L  ++   LL  P       +    +  +YLE R    ++ +R+ 
Sbjct: 80  AYRYGLKFLWMCLGQLLNSVLTALLFMPVFY----RLGLTSTYEYLEMRF---SRAVRLC 132

Query: 126 SAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDV 185
                +V    Y      A      Q   + +   +L T II T Y   GG  AVVWTDV
Sbjct: 133 GTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWTDV 192

Query: 186 VQAMFMLLTLIIMPILALVEIGG------LDRATQIIASVDPNKLHPFGGATGWAAIVFA 239
            Q + ML    ++    ++ +GG      L +    I  +D N   P    T W  +V  
Sbjct: 193 FQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNP-DPRSRYTFWTFVVG- 250

Query: 240 IGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVA 299
            G   W+  Y      V RY++     K  +  + I+ +   +++  A   G + F    
Sbjct: 251 -GTLVWLSMYGVNQAQVQRYVACR-TEKQAKLALLINQVGLFLIVSSAACCGIVMFVFYT 308

Query: 300 SGSI----KVEDPERIVPAMAIHF---LPGWVAGFVIAGIISAVMSTADSQLLVASSAIA 352
                   ++  P++ +P + +     LPG V G  +A   S  +STA + +   ++   
Sbjct: 309 DCDPLLLGRISAPDQYMPLLVLDIFEDLPG-VPGLFLACAYSGTLSTASTSINAMAAVTV 367

Query: 353 RDIYHKVLGQELGKKQMVNISR----------IVVAAVALV----------AMWFAITGP 392
            D+    L + L  +++V IS+          + VAA++ +           +   I+GP
Sbjct: 368 EDLIKPRL-RSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGP 426

Query: 393 KV---IYQMVATAWG--GLAVGFGPILTLSLW 419
            +   I  M   A    G+  G G  L LSLW
Sbjct: 427 LLGAFILGMFLPACNTPGVLAGLGAGLALSLW 458


>dbj|BAA24835.1| (D87920) sodium iodide symporter [Homo sapiens]
           Length = 643
           
 Score = 92.1 bits (225), Expect = 1e-17
 Identities = 111/452 (24%), Positives = 184/452 (40%), Gaps = 54/452 (11%)

Query: 9   FLIYLVILAYIGWW---ANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65
           F + L++   IG W   A    ++ + +F GGR++  L   LS  AS  S   +LG P  
Sbjct: 20  FALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLGVPSE 79

Query: 66  AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRIL 125
           A++ GL   W  +G L  ++   LL  P       +    +  +YLE R    ++ +R+ 
Sbjct: 80  AYRYGLKFLWMCLGQLLNSVLTPLLFMPVFY----RLGLTSTYEYLEMRF---SRAVRLC 132

Query: 126 SAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDV 185
                +V    Y      A      Q   + +   +L T II T Y   GG  AVVWTDV
Sbjct: 133 GTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWTDV 192

Query: 186 VQAMFMLLTLIIMPILALVEIGG------LDRATQIIASVDPNKLHPFGGATGWAAIVFA 239
            Q + ML    ++    ++ +GG      L +    I  +D N   P    T W  +V  
Sbjct: 193 FQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNP-DPRSRYTFWTFVVG- 250

Query: 240 IGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVA 299
            G   W+  Y      V RY++     K  +  + I+ +   +++  A   G + F    
Sbjct: 251 -GTLVWLSMYGVNQAQVQRYVACR-TEKQAKLALLINQVGLFLIVSSAACCGIVMFVFYT 308

Query: 300 SGSI----KVEDPERIVPAMAIHF---LPGWVAGFVIAGIISAVMSTADSQLLVASSAIA 352
                   ++  P++ +P + +     LPG V G  +A   S  +STA + +   ++   
Sbjct: 309 DCDPLLLGRISAPDQYMPLLVLDIFEDLPG-VPGLFLACAYSGTLSTASTSINAMAAVTV 367

Query: 353 RDIYHKVLGQELGKKQMVNISR----------IVVAAVALV----------AMWFAITGP 392
            D+    L + L  +++V IS+          + VAA++ +           +   I+GP
Sbjct: 368 EDLIKPRL-RSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGP 426

Query: 393 KV---IYQMVATAWG--GLAVGFGPILTLSLW 419
            +   I  M   A    G+  G G  L LSLW
Sbjct: 427 LLGAFILGMFLPACNTPGVLAGLGAGLALSLW 458


>emb|CAC00574.1| (AL109659) dJ1024N4.1 (novel Sodium:solute symporter family member
           similar to SLC5A1 (SGLT1)) [Homo sapiens]
           Length = 552
           
 Score = 91.7 bits (224), Expect = 2e-17
 Identities = 126/536 (23%), Positives = 225/536 (41%), Gaps = 69/536 (12%)

Query: 10  LIYLVILAYIGWWANKYTK--TEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAF 67
           +IY V +  +G W++      T   YF+ GR +       S  +S+    L +G  G+  
Sbjct: 35  VIYFVFVIAVGIWSSIRASRGTIGGYFLAGRSMSWWPIGASLMSSNVGSGLFIGLAGTGA 94

Query: 68  KAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSA 127
             GL          +  LA   +  P + I AG    +T+P YL+ R       + +   
Sbjct: 95  AGGLAVGGFEWNATWLLLALGWVFVP-VYIAAG---VVTMPQYLKKRFGGQRIQVYMSVL 150

Query: 128 AIILVFMTAYVAAQFAAGGKTFAQ---AFNVSVTTGILITVIILTAYVITGGFFAVVWTD 184
           ++IL   T      F+  G  F Q    +N+ ++TGIL+  ++   Y I GG  AV++TD
Sbjct: 151 SLILYIFTKISTDIFS--GALFIQMALGWNLYLSTGILL--VVTAVYTIAGGLMAVIYTD 206

Query: 185 VVQAMFMLLTLIIMPILALVEIG---GLD-RATQIIASVD----------PNKLH----P 226
            +Q + M+   +++  L   ++G   GL+ R  Q I +V           P+  H    P
Sbjct: 207 ALQTVIMVGGALVLMFLGFQDVGWYPGLEQRYRQAIPNVTVPNTTCHLPRPDAFHILRDP 266

Query: 227 FGGATGWAAIVFAIG-YASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLW 285
             G   W  ++F +   A+W   +     IV R +S +      + G  + G    + ++
Sbjct: 267 VSGDIPWPGLIFGLTVLATWC--WCTDQVIVQRSLSAKS-LSHAKGGSVLGGYLKILPMF 323

Query: 286 GAFFAGFLGFALVAS--GSIKVEDPERI-----------VPAMAIHFLPGWVAGFVIAGI 332
                G +  AL     G +  +  +RI            P + +  +P  + G +IA I
Sbjct: 324 FIVMPGMISRALFPDEVGCVDPDVCQRICGARVGCSNIAYPKLVMALMPVGLRGLMIAVI 383

Query: 333 ISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAI--- 389
           ++A+MS+  S    +S+    D++ +   +   ++ MV     VV  V +  +W  I   
Sbjct: 384 MAALMSSLTSIFNSSSTLFTIDVWQRFRRKSTEQELMVVGRVFVVFLVVISILWIPIIQS 443

Query: 390 TGPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGL---ISEVILEAKI 446
           +    ++  +      LA     +  L+++ KRVT+     G+ +GL   +  +ILE   
Sbjct: 444 SNSGQLFDYIQAVTSYLAPPITALFLLAIFCKRVTEPGAFWGLVFGLGVGLLRMILE--- 500

Query: 447 YGWAFNPKAPGFFGTLGQWFNGVPVFFINFF------VTLFIIIIVSLLTKP-PED 495
               F+  AP   G + +    +  F   +F      +T  +I+IVSL T P PE+
Sbjct: 501 ----FSYPAPA-CGEVDRRPAVLKDFHYLYFAILLCGLTAIVIVIVSLCTTPIPEE 551


>pir||D72694 hypothetical protein APE0972 - Aeropyrum pernix (strain K1)
           >gi|5104641|dbj|BAA79956.1| (AP000060) 460aa long
           hypothetical protein [Aeropyrum pernix]
           Length = 460
           
 Score = 90.1 bits (220), Expect = 6e-17
 Identities = 90/400 (22%), Positives = 182/400 (45%), Gaps = 25/400 (6%)

Query: 30  EDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYL 89
           E ++++ GR++    + ++  A+ +S ++++G  G A+  G+G+    +  L  T+    
Sbjct: 5   EGEFYLAGRRLTGFLSAMTYAATTYSSFMIVGLVGLAYFTGIGSLVFELAYLVATVILLS 64

Query: 90  LIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKT- 148
           L   R+   + + R    P  + A L   +  + + ++ + LV +  Y +AQ     +T 
Sbjct: 65  LFSRRVWRMSRE-RGWVSPGEMLADLL-GSPWVALTASLVFLVSLVPYASAQLKGIAETI 122

Query: 149 -----FAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILAL 203
                ++   N +    + + ++IL A+ +  G   VV TD  Q ++ML    ++ +   
Sbjct: 123 VAIAGYSPGDNTAYMVAVGVALLILLAWSLLAGVRGVVLTDAFQGLWMLTAGSLLFLWLA 182

Query: 204 VEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYAS-WIVGYLGQPHIVTRYMSV 262
             +     A++++++++   L     AT        IG+ + W+   +  P +V R    
Sbjct: 183 SRVFSKSGASEVLSAMESAGLFDMWSAT------LLIGFVTPWVFFAVTNPQVVQRLYMP 236

Query: 263 EDPRKLRRPGI--FISGIWTTIVLWGAFFAGFLGFALVASGSIKVEDPERI-VPAMAIHF 319
           +D   LRR  +  F+ G++ T+++      GFL  A V  G + +E   R  V    +  
Sbjct: 237 KDEESLRRMILYFFLFGLYYTVLVVAI---GFLARAGVELGILSIEPQGRDQVTPQLLSL 293

Query: 320 LPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAA 379
               +A  V   I++A +STADS +L  +S+ +RDI   VL   L +K  + +     A 
Sbjct: 294 AHPLLAALVFTSIVAASVSTADSIILALASSASRDIGLLVL--RLDEKGRLRLGYAAAAL 351

Query: 380 VALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLW 419
             ++   FA T    I Q+   +   + +G  P+ T++ W
Sbjct: 352 FTVLMAVFAATRIGYIVQLSVLS-SVMLLGLAPV-TIAAW 389


>emb|CAB94614.1| (AL359214) putative permease [Streptomyces coelicolor A3(2)]
           Length = 532
           
 Score = 89.7 bits (219), Expect = 8e-17
 Identities = 114/525 (21%), Positives = 214/525 (40%), Gaps = 59/525 (11%)

Query: 1   MNFGILFGFLIYLVILAYIGWWANKYTKTE-----DQYFVGGRKVHVLAATLSDKASDFS 55
           MN   L  F+ + V++  +G+ A ++ + E     D++ +GGR               ++
Sbjct: 1   MNGVALAVFIFFFVLVTAMGFLAARWRRAENEHSLDEWGLGGRSFGTWVTWFLLGGDLYT 60

Query: 56  GWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIG---PRLRIYAGKFRAITLPDYLE 112
            +  +  P + + AG   F+A    +  T+  Y LI    PRL   + K   +T  D++ 
Sbjct: 61  AYTFVAVPAAIYAAGASGFFA----VPYTILVYPLIFTFLPRLWSVSHKHGYVTTSDFVR 116

Query: 113 ARLKDNTKLIRILSAAIILVFMTAYVAAQFAA----------GGKTFAQAFNVSVTTGIL 162
            R    +K + +  A   ++    Y+A Q             GG      F   +   +L
Sbjct: 117 GRF--GSKGLSLAVAVTGILATMPYIALQLVGIQAVLDVMGVGGGEDTNWFVKDLP--LL 172

Query: 163 ITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLD----RATQIIAS 218
           I   +L AY  + G  A      V+   + + + +  I   +++GG D     A+    +
Sbjct: 173 IAFGVLAAYTYSSGLRAPALIAFVKDTLIYIVIAVAIIYIPIKLGGFDDIFASASDKFTA 232

Query: 219 VDPNKLHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGI 278
                + P  G   W     A+G A  +  Y   PH +T  +S      +RR        
Sbjct: 233 AGKGGVVPDAGGQ-WTYATLALGSALALFMY---PHSITATLSSRSREVIRRN------- 281

Query: 279 WTTIVLWGAFFAGFL---GFALVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISA 335
            TTI+   +   G L   GF  +A+G +KV++ +  +P +  +  P W AG   A I   
Sbjct: 282 -TTILPLYSLMLGLLALLGFMAIAAG-VKVDNGQLAIPQLFENMFPDWFAGVAFAAIGIG 339

Query: 336 VMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVI 395
            +  A    + A++   R+IY   +  +   +Q   +S++V   V + A+ F +   K +
Sbjct: 340 ALVPAAIMSIAAANLFTRNIYKDFIKPDATPQQETKVSKLVSLLVKVGALIFVLGMDKTV 399

Query: 396 ---YQMVATAWGGLAVGFGPIL--TLSLWWKRVTKEAG-IVGMAYGLISE--VILEAKIY 447
              +Q++   W  +   F  ++    + W+ R     G  VGM YG ++   V    + +
Sbjct: 400 AINFQLLGGIW--ILQTFPALVGGLFTRWFHRWALLGGWAVGMVYGTVAAYGVASPTQKH 457

Query: 448 GWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTLFIIIIVSLLTKP 492
               + + PG  G +G  + G+  F +N  VT+ +  ++  +  P
Sbjct: 458 FGGSSDEIPG-IGEIG--YIGLTAFVLNVLVTVVLTFVLRAVKAP 499


>gi|11498804 pantothenate permease (panF-2) [Archaeoglobus fulgidus]
           >gi|7442767|pir||D69400 pantothenate permease (panF-2)
           homolog - Archaeoglobus fulgidus
           >gi|2649380|gb|AAB90040.1| (AE001021) pantothenate
           permease (panF-2) [Archaeoglobus fulgidus]
           Length = 474
           
 Score = 88.9 bits (217), Expect = 1e-16
 Identities = 107/480 (22%), Positives = 196/480 (40%), Gaps = 37/480 (7%)

Query: 10  LIYLVILAYIGWWANK-YTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFK 68
           + +LV    +G++  K   K+E+ Y V  R +  +   ++   +      +LG   SA+ 
Sbjct: 1   MYFLVTTLGVGFYLMKRMEKSEEDYLVAKRGLGAVPVGVTLALTVLGTPHILGVMESAYD 60

Query: 69  AGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAA 128
            GL A W             L  G     +A K +  ++P++L+    +    +R++  A
Sbjct: 61  IGLPAVWFSFAHAIMLAIVCLFTGR----WARKLKVESVPEFLDVIFSNYW--LRLMVGA 114

Query: 129 IILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQA 188
           +I   +      +    G   +     S+  GI+I  +I   YV+  G   V W +V+ A
Sbjct: 115 VIAGAIFGICTLETQGLGVFVSILTGTSIEVGIVIGALIGILYVVLSGMKEVAWLNVLNA 174

Query: 189 MFMLLTLIIMP-ILALVEIGGLDRATQIIASVD-PNKLHPFGGATGWAAIV-FAIGYASW 245
           + + + +I    +L      G +   +   S D   KL+ FG    W   V FA+     
Sbjct: 175 VILYIGIIAATFVLGSGLQNGWEGVNEFYISNDLAGKLNIFGS---WEVFVGFALVNVLA 231

Query: 246 IVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAF--FAGFLGFALVASGSI 303
            V + G          +      + P +    +   + + G+F  FA  +G A  A+   
Sbjct: 232 TVFFQG-----ISQQGLHAALAAKSPDVLRKAMLIAVPVNGSFAVFAAVMGMAARATPEF 286

Query: 304 KVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQE 363
                +   PAM +  LP W +  ++A  + AV+S+    LL  ++    DIY  VL   
Sbjct: 287 AELGAKTATPAMIVSVLPTWASALLLATCLVAVLSSYAITLLAPTTIFVNDIYKAVLKPN 346

Query: 364 LGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMV-ATAWGGLAVGFGPILTLSLWWKR 422
              ++++ +SRI+   +A+ A+  A++ P ++  M+   +W    V     +   L+WKR
Sbjct: 347 ASHEELLRLSRILTVLLAVAALIPAVSLPPILAAMMWLFSW---LVPVFWFVIFGLFWKR 403

Query: 423 VTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTLFI 482
               A        +I+ +++   I  W   P  P   G  G W + V   ++   VTL I
Sbjct: 404 SAPAA--------IITCLLVWVTINAWTMTP-LPEVLGAPG-WLHQV---YLALIVTLVI 450


>pir||S68513 thyroid iodide transport protein - rat >gi|1399954|gb|AAB03338.1|
           (U60282) thyroid sodium/iodide symporter NIS [Rattus
           norvegicus]
           Length = 618
           
 Score = 87.4 bits (213), Expect = 4e-16
 Identities = 111/453 (24%), Positives = 182/453 (39%), Gaps = 44/453 (9%)

Query: 9   FLIYLVILAYIGWW---ANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65
           F   L++   IG W   A    ++ D +F GGR++  +   LS  AS  S   +LG P  
Sbjct: 20  FATMLLVSTGIGLWVGLARGGQRSADDFFTGGRQLAAVPVGLSLAASFMSAVQVLGVPAE 79

Query: 66  AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRIL 125
           A + GL   W   G L  +L    L  P       +    +   YLE R    ++ +R+ 
Sbjct: 80  AARYGLKFLWMCAGQLLNSLLTAFLFLPIFY----RLGLTSTYQYLELRF---SRAVRLC 132

Query: 126 SAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDV 185
                LV    Y      A      Q   + +   +L T II T Y   GG  AVVWTDV
Sbjct: 133 GTLQYLVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTLYTTVGGMKAVVWTDV 192

Query: 186 VQAMFMLLTLIIMPILALVEIGGLDRATQI--------IASVDPNKLHPFGGATGWAAIV 237
            Q + ML+   ++    ++ +GG      +        +   DP+   P    T W  IV
Sbjct: 193 FQVVVMLVGFWVILARGVILLGGPRNVLSLAQNHSRINLMDFDPD---PRSRYTFWTFIV 249

Query: 238 FAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFAL 297
              G   W+  Y      V RY++     K +   + ++ +   +++  A   G + F  
Sbjct: 250 G--GTLVWLSMYGVNQAQVQRYVACHTEGKAKL-ALLVNQLGLFLIVASAACCGIVMFVY 306

Query: 298 VASG----SIKVEDPERIVPAMAIHF---LPGWVAGFVIAGIISAVMSTADSQLLVASSA 350
                   + ++  P++ +P + +     LPG V G  +A   S  +STA + +   ++ 
Sbjct: 307 YKDCDPLLTGRISAPDQYMPLLVLDIFEDLPG-VPGLFLACAYSGTLSTASTSINAMAAV 365

Query: 351 IARDIYHKVLGQELGKKQMVNISR----IVVAAVALVAMWFAITGPKVIYQMVATAWGGL 406
              D+  K     L  +++V IS+    I  +A   VA   ++ G  V+ Q   T  G +
Sbjct: 366 TVEDLI-KPRMPGLAPRKLVFISKGLSFIYGSACLTVAALSSLLGGGVL-QGSFTVMGVI 423

Query: 407 AVGFGPIL---TLSLWWKRVTKEAGIVGMAYGL 436
           +   GP+L   TL +          + G+A GL
Sbjct: 424 S---GPLLGAFTLGMLLPACNTPGVLSGLAAGL 453


>pir||G83610 probable sodium:solute symporter PA0287 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9946130|gb|AAG03676.1|AE004466_10 (AE004466)
           probable sodium:solute symporter [Pseudomonas
           aeruginosa]
           Length = 461
           
 Score = 87.4 bits (213), Expect = 4e-16
 Identities = 106/463 (22%), Positives = 194/463 (41%), Gaps = 41/463 (8%)

Query: 10  LIYLVILAYIGWWANKYTKTEDQYFVGGRKVH------VLAATLSDKASDFSGWLMLGYP 63
           L+Y + +  +GW+  +  K++  + V GR++        +AA +   AS   G + LGY 
Sbjct: 9   LVYALAMLGLGWYGMRKAKSQSDFLVAGRRLGPGLYLGTMAAVVLGGASTI-GTVKLGY- 66

Query: 64  GSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIR 123
               + GL   W       G +   L+   ++     + R  T+   LE R + +++LI 
Sbjct: 67  ----QFGLSGLWLVFMLGLGIIVLSLVFSRQI----ARLRVFTVTQVLEQRYQASSRLIG 118

Query: 124 --ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVV 181
             ++ A  ++V +TA +A      G      F +     IL    I+  Y + GG +++ 
Sbjct: 119 GVVMVAYDLMVAVTATIAI-----GSVTEVVFGIPRIPAILCGGGIVIVYSVIGGMWSLT 173

Query: 182 WTDVVQAMFML--LTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFA 239
            TD++Q +     + L+++P L++   GGL R  +++    P      G       + + 
Sbjct: 174 LTDIIQFVIKTVGIFLVLLP-LSIDGAGGLARMQEVL----PAGFFDLGHIGLDTILTYF 228

Query: 240 IGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVA 299
           + Y     G L    I  R  +      +R  G+   G     +L+GA  A     A V 
Sbjct: 229 LLY---FFGALIGQDIWQRVFTARSETVVRYAGL---GAGVYCMLYGAACALIGAAARVL 282

Query: 300 SGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKV 359
              + V  PE     +    L   + G V+A  +SA+MSTA   LL A++ +  DIY + 
Sbjct: 283 LPDLAV--PENAYAEITREVLAPGLRGLVVAAALSAIMSTASGCLLAAATVLQEDIYARF 340

Query: 360 LGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLW 419
           L    G    + +SR +   + +  +  A     VI   ++ A+  L  G    +  +L 
Sbjct: 341 L--RPGTTSDIRLSRCITLLMGVAMLVLACLVNDVI-AALSIAYNLLVGGLLVPIVGALL 397

Query: 420 WKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTL 462
           W+R + +  I  +  G ++ +   A+    A +P   G   +L
Sbjct: 398 WRRASPQGAIASIVAGCLAVIACMARDGLLANSPIVYGLLASL 440


>sp|P23723|PUTP_KLEPN SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)
           >gi|443996|emb|CAA52889.1| (X74934) proline permease
           [Klebsiella pneumoniae]
           Length = 160
           
 Score = 84.7 bits (206), Expect = 3e-15
 Identities = 42/115 (36%), Positives = 64/115 (55%), Gaps = 1/115 (0%)

Query: 5   ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           +L  F++Y+  +  IG+ A + TK  D Y +GGR +      LS  ASD SGWL++G PG
Sbjct: 7   MLVTFIVYIFGMVLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66

Query: 65  SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDN 118
           + F +G+   W  IG   G   ++ L+  RLR++      A+T PDY   R +D+
Sbjct: 67  AIFISGISESWIAIGLTLGAWINWKLVAGRLRVHTEVNNNALTXPDYFTGRFEDH 121


>prf||2204393A Na/I symporter [Rattus norvegicus]
           Length = 618
           
 Score = 83.9 bits (204), Expect = 4e-15
 Identities = 106/457 (23%), Positives = 183/457 (39%), Gaps = 41/457 (8%)

Query: 2   NFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLG 61
           ++G+    L+    +  +   A    ++ D +F GGR++  +   LS  AS  S   +LG
Sbjct: 16  DYGVFATMLLVSTGIGLMVGLARGGQRSADDFFTGGRQLAAVPVGLSLAASFMSAVQVLG 75

Query: 62  YPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKL 121
            P  A + GL   W   G L  +L    L  P       +    +   YLE R    ++ 
Sbjct: 76  VPAEAARYGLKFLWMCAGQLLNSLLTAFLFLPIFY----RLGLTSTYQYLELRF---SRA 128

Query: 122 IRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVV 181
           +R+      LV    Y      A      Q   + +   +L T II T Y   GG  AVV
Sbjct: 129 VRLCGTLQYLVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTLYTTVGGMKAVV 188

Query: 182 WTDVVQAMFMLLTLIIMPILALVEIGGLDRATQI--------IASVDPNKLHPFGGATGW 233
           WTDV Q + ML+   ++    ++ +GG      +        +   DP+   P    T W
Sbjct: 189 WTDVFQVVVMLVGFWVILARGVILLGGPRNVLSLAQNHSRINLMDFDPD---PRSRYTFW 245

Query: 234 AAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFL 293
               +  G   W+  Y      V RY++     K +   + ++ +   +++  A   G +
Sbjct: 246 T--FYVGGTLVWLSMYGVNQAQVQRYVACHTEGKAKL-ALLVNQLGLFLIVASAACCGIV 302

Query: 294 GFALVASG----SIKVEDPERIVPAMAIHF---LPGWVAGFVIAGIISAVMSTADSQLLV 346
            F          + ++  P++ +P + +     LPG V G  +A  +S  +STA + +  
Sbjct: 303 MFVYYKDCDPLLTGRISAPDQYMPLLVLDIFEDLPG-VPGLFLACAVSGTLSTASTSINA 361

Query: 347 ASSAIARDIYHKVLGQELGKKQMVNISR----IVVAAVALVAMWFAITGPKVIYQMVATA 402
            ++    D+  K     L  +++V IS+    I  +A   VA   ++ G  V+ Q   T 
Sbjct: 362 MAAVTVEDLI-KPRMPGLAPRKLVFISKGLSFIYGSACLTVAALSSLLGGGVL-QGSFTV 419

Query: 403 WGGLAVGFGPIL---TLSLWWKRVTKEAGIVGMAYGL 436
            G ++   GP+L   TL +          + G+A GL
Sbjct: 420 MGVIS---GPLLGAFTLGMLLPACNTPGVLSGLAAGL 453


>emb|CAC16517.1| (AL450223) putative integral membrane transport protein
           [Streptomyces coelicolor]
           Length = 523
           
 Score = 83.5 bits (203), Expect = 6e-15
 Identities = 110/509 (21%), Positives = 201/509 (38%), Gaps = 26/509 (5%)

Query: 10  LIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKA 69
           ++YL+ +A+IG       K+   YFVG   +     + S  A++ S   ++  PG A+  
Sbjct: 10  VVYLIGIAWIGLRKAGRQKSAKDYFVGEGHMPWWTVSFSVVATETSVLTVISVPGGAYSG 69

Query: 70  -GLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAA 128
            G G     +G + G +    ++ P  +   G F  ++   YL  R     KL  + S  
Sbjct: 70  QGFGNVELALGYVVGRVVVATVLIPLYK--RGGF--VSAYQYLGDRF--GLKLQGLASVT 123

Query: 129 IILVFMTAYVAAQFAAGG--KTFAQAFNVSVTTGILITVIILTAYVIT--GGFFAVVWTD 184
            +   + A     FA+    K     F V  +   +I VI L   V T  GG  AV+WTD
Sbjct: 124 FVFTRLLAEGVRLFASAIPIKLLLDEFGVHASYRAIIIVITLITVVYTYLGGIKAVIWTD 183

Query: 185 VVQAMFMLLTLIIMPILALVEIGG------LDRATQIIASVDPNKLHPFGGATGWAAIVF 238
            +Q +  L   ++   +    +GG      LD     +   D N  H     + +A    
Sbjct: 184 AIQMVLYLGGAVLAVAVLSAHVGGDGYARALDAGKFQLFDTDFNLAHIL--TSPFALPTA 241

Query: 239 AIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALV 298
            IG A + +   G   ++ + +      +  +  +  SG++ T+        G L ++  
Sbjct: 242 IIGGAIFAMASHGSDQLIVQRVLATRTLREGQKAMIASGVFVTVQFAAFSLVGALLWSYN 301

Query: 299 ASGS---IKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355
              S   + +   + + P   +H LP  V+G ++AGI+ A M +  S L   S++   DI
Sbjct: 302 EGRSFAELGLSSSDNLYPEFILHGLPVVVSGLLVAGILGAAMGSLSSALNSMSNSTVADI 361

Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415
            H        ++ ++ ++R +    A +   FA         +  T        +G +L 
Sbjct: 362 IHSFFRSTPSEEALLRLARWMTLVWATLMAVFACAFSASTGNVYLTGLTIAGYTYGALLG 421

Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFIN 475
             L  + V +   +  +   L++  ++   + G   +    G   T+ Q      +  I 
Sbjct: 422 AFLLGRLVKRANEVDSVVAFLVTIGVMTYIVRGVKIDVTTGG--TTVSQAIAAQWLVPIG 479

Query: 476 FFVTLFIIIIVSLLTKPPED--VVKLHEE 502
             +TL +  ++SL  + PE   V  L EE
Sbjct: 480 VLITLLVGGVLSLFHRAPEPSAVTALDEE 508


>gb|AAK42614.1| Metabolite permease, putative [Sulfolobus solfataricus]
           Length = 505
           
 Score = 82.3 bits (200), Expect = 1e-14
 Identities = 103/492 (20%), Positives = 208/492 (41%), Gaps = 26/492 (5%)

Query: 9   FLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFK 68
           F++++ +  Y  +W         ++ + GR++  +       A  ++ +  +  P S + 
Sbjct: 14  FIVFIFLGFYGAFWRKGNLDLLHEWGLAGRRLGTVLVWFLMGADLYTAYTFIAVPSSLYA 73

Query: 69  AGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAA 128
            G   F+A +  +  T A  +L  P+L I +     +T  D+++ R   N+ ++  L A 
Sbjct: 74  KGAIYFFA-VPYVSLTFAIAMLTMPKLWIVSRNRGYVTAADFVKDRF--NSSILAALIAL 130

Query: 129 IILVFMTAYVAAQFAAGGKTFAQAFNVSVTTG-------ILITVIILTAYVITGGFFAVV 181
             +V    Y+A Q   G K+  Q   + +          ++++ IIL A+  T G     
Sbjct: 131 TGVVAELPYIALQIV-GMKSVLQMMLLGIGNATLVSEISLIVSFIILAAFTYTSGLRGAA 189

Query: 182 WTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIG 241
            T V + + + +T+I + ++  ++ GG   A  +I S + +  +    +    A  +++ 
Sbjct: 190 LTGVFKDILIWITVISVIVIVPLQYGGFTHAFSVINSANLSARYTTLPSNLQIAY-WSLF 248

Query: 242 YASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIF--ISGIWTTIVLWGAFFAGFLGFALVA 299
             S +  YL  PH +   +S +D  +L        I GI   I+   A F G L +A+  
Sbjct: 249 LGSALALYL-YPHSINGSLSADDKNRLMYSTALLPIYGIGLAII---ALF-GILVYAVPN 303

Query: 300 SGSIKVE-DPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHK 358
           + S+  +     +VPA+    +P W AG ++ GI    +  A    + AS+ + R++  K
Sbjct: 304 ALSVVSKYGGALVVPALITSTMPDWAAGIMLLGIFVGGLVPAAIMAIAASNLLVRNVI-K 362

Query: 359 VLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSL 418
            +   +  K    +++ + A +  +A+ F    P      +    G L     P + L L
Sbjct: 363 EVNPSITPKGETTLAKWISAVIKFLALAFVFLVPSTYAINLQLLGGILITQTLPAVFLGL 422

Query: 419 WWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTL-GQWFNGVPVFFINFF 477
           + K     A   G   G+IS   +    + +   P+A   + TL G  +  V    +N  
Sbjct: 423 YTKWFNPWALTAGWTTGIISGTYM---FFTFGL-PRATSLYPTLFGLMYAAVIALVLNLV 478

Query: 478 VTLFIIIIVSLL 489
           V++   ++ + L
Sbjct: 479 VSVIGTLVANAL 490


>gb|AAA66065.1| (U08813) 597 aa protein related to Na/glucose cotransporters
           [Oryctolagus cuniculus] >gi|1092917|prf||2102228A
           Na/glucose transporter [Oryctolagus cuniculus]
           Length = 597
           
 Score = 81.5 bits (198), Expect = 2e-14
 Identities = 116/532 (21%), Positives = 215/532 (39%), Gaps = 68/532 (12%)

Query: 11  IYLVILAYIGWWAN--KYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFK 68
           +Y  +   +G W++      T   YF+ GR +       S   S     L +G  GS   
Sbjct: 27  VYFALNVAVGIWSSCRASRNTVSGYFLAGRDMTWWPIGASLFGSSEGSGLFIGLAGSGAA 86

Query: 69  AGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAA 128
            GL          +  LA   + G    IY      +TL +Y++ R     ++   LS  
Sbjct: 87  GGLAVAGFDWNATYVLLALAWVFGA---IYISS-EIVTLAEYIQKRF-GGQRIRMYLSVL 141

Query: 129 IILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQA 188
            +L+ +   ++    AG          +     ++T+ I   Y ITGG  AV++TD +Q 
Sbjct: 142 SLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLTITALYTITGGLVAVIYTDALQT 201

Query: 189 MFMLLTLIIMPILALVEIGGLDRATQIIASVDPNK--------------LH----PFGGA 230
           + M++  +I+ I A  +I G  +     A   P++              +H    P+ G 
Sbjct: 202 LIMVVGAVILAIKAFHQIDGYGQMEAAYARAIPSRTVANTTCHLPRADAMHMFRDPYTGD 261

Query: 231 TGWAAIVFAIG-YASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGI----WTTIVLW 285
             W  + F +   A+W   +     IV R +S  +    +   I  S +       +++ 
Sbjct: 262 LPWTGMTFGLTIMATWY--WCTDQVIVQRSLSARNLNHAKAGSILASYLKMLPMGLMIMP 319

Query: 286 G----AFFAGFLGFALVASGSIKVEDPE-----RIVPAMAIHFLPGWVAGFVIAGIISAV 336
           G    A F   +G  +V S  ++    E        P + +  +P  + G +IA ++ A+
Sbjct: 320 GMISRALFPDEVG-CVVPSECLRACGAEIGCSNIAYPKLVMELMPVGLRGLMIAVMMPAL 378

Query: 337 MSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAM-WFAIT----- 390
           MS+  S    +S+    DI+ + L     +++++ + R+V+  +  V++ W  +      
Sbjct: 379 MSSLSSIFNSSSTLFTMDIWRR-LRPCASERELLLVGRLVIVVLIGVSVAWIPVLQGSNG 437

Query: 391 GPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGL---ISEVILEAKIY 447
           G   IY    T+   LA     + TL ++W+R  ++    G+  GL    + ++LE    
Sbjct: 438 GQLFIYMQSVTS--SLAPPVTAVFTLGIFWQRANEQGAFWGLLAGLAVGATRLVLE---- 491

Query: 448 GWAFNPKAP-GFFGTLGQWFNGVPVFFINFFVTLFII-----IIVSLLTKPP 493
               +P  P G   T     +   + +++F V LF++     +  SLLT PP
Sbjct: 492 --FLHPAPPCGAADTRPAVLS--QLHYLHFAVALFVLTGAVAVGGSLLTPPP 539


>pir||A82432 sodium/solute symporter VCA0667 [imported] - Vibrio cholerae (group
           O1 strain N16961) >gi|9658084|gb|AAF96568.1| (AE004396)
           sodium/solute symporter [Vibrio cholerae]
           Length = 513
           
 Score = 81.1 bits (197), Expect = 3e-14
 Identities = 89/472 (18%), Positives = 192/472 (39%), Gaps = 36/472 (7%)

Query: 11  IYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAG 70
           IYL++   I W+ N+ +     +  GGR+     A +S  A+  S    +G PG  +++G
Sbjct: 12  IYLILTILISWFVNQRSIGNTDFSTGGRQFGWFTAGVSILATYISAMTFIGMPGWVYQSG 71

Query: 71  LGAFWAGIG---CLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSA 127
           + A    +     +F  +  ++ +  R+          ++ +YLE R     + I  +  
Sbjct: 72  MEALNIHLNYPIVIFFAVVFFIPVFYRMGF-------TSIYEYLEHRFGVYARTINSVVF 124

Query: 128 AIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQ 187
            ++    +  +    A       Q   +S+   I+   +    Y   GG   V+WTD++Q
Sbjct: 125 ILVQCISSGVILYAIAL---ILIQILPISIVEAIVYITLFTACYTYAGGISTVIWTDMLQ 181

Query: 188 AMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIV 247
           +  ++   + + +L L+++ G+   ++   ++   +       T WA +V A+ +    V
Sbjct: 182 SAVLIAGSVAIFVLLLLQVDGVHGVSREQLNIINLQFDLGVDTTLWAGVV-AVSFLHMSV 240

Query: 248 GYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVASGSIKVED 307
              G   ++ +        K  +  + + G       +GAFF  F    L    SI  ++
Sbjct: 241 --YGTNQLIIQRTLATRCEKTAQKSMLLCG-------YGAFFIYFFFALLGVLLSIFYQE 291

Query: 308 -----PERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQ 362
                   ++     H    WV G +I+ + +A MST DS     ++    D+Y + + +
Sbjct: 292 RHFTNSNEVILDFVFHHTNPWVIGLIISALAAAAMSTLDSTYNSMATVATFDLYQRFIRR 351

Query: 363 ELGKKQMVNISR---IVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLW 419
                    ++R   +V A + ++    A++   V+  + +     + +  G  + L L+
Sbjct: 352 NAPDHHYQAVARKMSLVAAGLVVIPALLAVSNESVLKTIASLTSIFVGIRLGSFV-LGLF 410

Query: 420 WKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPV 471
             +  ++  I G    + +  +L A++   A+   AP   GT+    +GV +
Sbjct: 411 SNQANEKGVIAGSIISIAA--VLGARLMDIAWPWFAP--IGTVFFLVSGVVI 458


>pir||T28017 hypothetical protein ZK822.5 - Caenorhabditis elegans
           >gi|3881819|emb|CAA98070.1| (Z73898) Similarity to
           Salmonella sodium/proline symporter (SW:PUTP_SALTY),
           contains similarity to Pfam domain: PF00474
           (Sodium:solute symporter family), Score=5.7,
           E-value=1.7e-08, N=1~cDNA EST yk398b5.3 comes from this
           gene~cDNA EST yk440a11.3 comes >
           Length = 577
           
 Score = 79.6 bits (193), Expect = 8e-14
 Identities = 90/368 (24%), Positives = 154/368 (41%), Gaps = 25/368 (6%)

Query: 30  EDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYL 89
           +++Y +GGR++  L   LS   +  SG LMLG P   F+ G    W  +  + G  +  +
Sbjct: 45  KEEYLMGGRQLPPLPVALSLLTTFLSGILMLGVPAEMFQRG-AQIW--LNFVIGVASSIV 101

Query: 90  LIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTF 149
                L ++  K ++  L +Y   R   N+ LIR L + + L+F   Y++    A     
Sbjct: 102 TCFVFLPVFH-KMKSTCLHEYFIHRY--NSILIRRLFSLLFLLFTIVYMSVVLYAPSVAL 158

Query: 150 AQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFML--LTLIIMPILALVEIG 207
           +    ++    +LI     T Y   GG  AVVWTD +QA+ M   +  +I   L+   +G
Sbjct: 159 SPVLQINKWYLVLIFGCTTTLYTCLGGLKAVVWTDSLQAVIMYTGVFTLIYKGLSHPRVG 218

Query: 208 GLDRATQIIASVDPNKLHPFGGATGWAA-------IVFAIGYASWIVGYLGQPHIVTRYM 260
           GL+R   I  + D  ++    G   W         I    G   W+  +      + RY 
Sbjct: 219 GLERVLSI--AWDSGRISEL-GRMDWRIDQYNSLWINLFSGTIVWLASFGVNQLAIQRYA 275

Query: 261 SVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFAL------VASGSIKVEDPERIVPA 314
           S+   +  +   I+    +T +    A F GF+  A       + +G +K  D   I  A
Sbjct: 276 SLPSLKVAQSIIIYTLAPFTVLCSIVA-FVGFIALAYFYNCNPLETGEVKESDHITISFA 334

Query: 315 MAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISR 374
             I      + G  ++ I+SA +ST  S +   ++AI  D     L  ++       +++
Sbjct: 335 RDILQPTPGLFGLYVSCIMSATLSTLSSGMNSMAAAIYEDFLKNSLDGKITDTGATRLNK 394

Query: 375 IVVAAVAL 382
           I+V    L
Sbjct: 395 IIVLICGL 402


>pir||T32478 hypothetical protein F52H2.4 - Caenorhabditis elegans
           >gi|2435612|gb|AAB71314.1| (AF026214) F52H2.4 gene
           product [Caenorhabditis elegans]
           Length = 466
           
 Score = 78.0 bits (189), Expect = 2e-13
 Identities = 90/397 (22%), Positives = 165/397 (40%), Gaps = 40/397 (10%)

Query: 101 KFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTG 160
           + +  T+ +Y E R        R ++ ++  V M  Y +    A     A   N+ +T  
Sbjct: 26  RLKLTTIYEYFERRFDYKC---RFVTTSLFCVQMILYNSVALYAPSLAIASITNIPITVS 82

Query: 161 ILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIAS-- 218
           ILIT ++   Y+  GG  A + T  +Q + + LT+  +  ++L E+   D  T ++    
Sbjct: 83  ILITAVLSAFYISVGGVKAGIHTSAIQMLLIFLTMTFIISISLREMSIHDVYTSVVHGKR 142

Query: 219 --VDPNKLHPFG----GATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPG 272
             ++P   H       G TG    +FA    S           + RYM++ D  K  +  
Sbjct: 143 FRINPTIRHSVWSLLIGGTGNILALFAANQLS-----------IQRYMAM-DTLKSAQKV 190

Query: 273 IFISGIWTTIVLWGAFFAGFLGFALVASGSIKVEDPERIVPAMAIHF---LPGWVAGFVI 329
           + ++ +  TI+L      GFL +A       ++ +   ++P   +      PG V G   
Sbjct: 191 VLLNIVCNTIILVSYVSVGFLIYAHYKDCHPQIGNANELLPRFVMDVTSKYPGSV-GLFA 249

Query: 330 AGIISAVMSTADSQLLVASSAIARDIYHKVLGQE-----LGKKQMVNISRIVVAAVALVA 384
           A + SA +ST  +     SS +  D++ KV  +      L   Q+ N  RI+   ++ ++
Sbjct: 250 AAVYSAGISTLSASFTAVSSIVINDVW-KVYRERRKMAPLRNDQVQNAMRILPIVLSFIS 308

Query: 385 MWFAITGPKVIYQMVATAWGGLAVGFGPIL---TLSLWWKRVTKEAGIVGMAYGLISEVI 441
           ++ A     +   ++  ++     G GP+L    + L+  RV ++A +V    GLI  +I
Sbjct: 309 IFVAFLCSMLQSIILQVSFIVFGAGGGPVLGSFVVGLFVPRVKEKAALV----GLIGSII 364

Query: 442 LEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFV 478
           +   I   +   K       LGQ  N    +F   F+
Sbjct: 365 VCFSISIGSVLVKVKPVALELGQCSNQTLTYFDESFI 401


>emb|CAB88444.1| (AL353815) putative sodium-coupled permease [Streptomyces
           coelicolor A3(2)]
           Length = 527
           
 Score = 76.1 bits (184), Expect = 1e-12
 Identities = 102/476 (21%), Positives = 188/476 (39%), Gaps = 42/476 (8%)

Query: 1   MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60
           +++ +L G   Y  ++  IG W++K       +F  G K+    + +S   S +S  +  
Sbjct: 4   LDWSVLIG---YFAVMVAIGVWSHKRVDDVSDFFTAGGKMPWWLSGISHHMSGYSAVMFT 60

Query: 61  GYPGSAFKAGLGAF--WAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDN 118
           GY G A+  G+ +F  W+      G      L  PR+     +    +  +YL+ R    
Sbjct: 61  GYAGIAYTYGVTSFVTWS-FPIALGVAIGSKLFAPRINRLRSRLHVASPLEYLKNRYNLP 119

Query: 119 TKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFF 178
           T+     S  ++ +     VAA++AA     +    +++  GILIT +I   Y   GG +
Sbjct: 120 TQQALAWSGMLLKI---VDVAAKWAAIATLLSVFTGITLNQGILITGVITGIYCTIGGLW 176

Query: 179 AVVWTDVVQAMFMLLTLIIMPILALVEIG------GLDRATQIIASVDPNKLHPFGGATG 232
           A   T++ Q +  LL  + M +  ++++G      G+     +     P  + P+G  T 
Sbjct: 177 ADALTELGQFIIQLLAGVAMFVAVVMKLGDHGGFFGVWDEPALQGHGKP-LVGPYG--TV 233

Query: 233 WAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGA--FFA 290
           +      I    +  G L Q     RYM+  + R+  R     + +W   ++W    FF 
Sbjct: 234 FLLAFLFIKLFEYNGGMLNQAQ---RYMATANAREATRGARLSAVLW---LVWPLVLFFP 287

Query: 291 GFLGFALVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSA 350
            ++   LV S      D   +   M    LP  + G VI G  S  M+   S     ++ 
Sbjct: 288 MWMSPLLVESQKADGSDSYAL---MTEQLLPHGLLGLVIVGFFSHTMAMCSSDANAIAAV 344

Query: 351 IARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGP----------KVIYQMVA 400
             RD+   +  +  G  Q   +    +  V  + +  A+              V+ + VA
Sbjct: 345 FTRDVAPVLSKRARGWGQRSGLLAARLTTVIFLGLSMAVATQVDSPTFKDIITVVIKWVA 404

Query: 401 TAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAP 456
              G +A+    +L L   ++R    A +     GL++  ++   I  W+ +   P
Sbjct: 405 GLMGPIAIPM--MLGLLRPFRRSGPTAALTSWGLGLVAFWLVNYPI-NWSVDGGVP 457


>gb|AAB39701.1| (U72716) unknown [Drosophila melanogaster]
           >gi|7302091|gb|AAF57192.1| (AE003779) CG2187 gene
           product [Drosophila melanogaster]
           Length = 623
           
 Score = 74.9 bits (181), Expect = 2e-12
 Identities = 96/383 (25%), Positives = 167/383 (43%), Gaps = 53/383 (13%)

Query: 1   MNFGIL--FGFLIYLVILAYIGWWANKYTK---TEDQYFVGGRKVHVLAATLSDKASDFS 55
           + FG+   F F+I L   A IG +   ++K   T ++Y  GG+K+  L   +S  AS  S
Sbjct: 22  LRFGLTDYFVFVIMLGASAGIGVYFGFFSKSKNTTEEYLRGGKKMQTLPIAISLVASQLS 81

Query: 56  GWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLP---DYLE 112
           G  ++  P  ++  G          +F  LA  ++I   + I    F    +    +YLE
Sbjct: 82  GIAIMSIPAESYTYGFNY-------IFVVLAMLVVIPILIYIIVPVFYENNVSNCYEYLE 134

Query: 113 ARLKDNTK-LIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAY 171
            R    T+ L+         + +  Y+     A    FAQ   +++    ++   I   Y
Sbjct: 135 MRFNKRTRQLVTFFFVTNSFLMLPVYMFIPSLA----FAQVTGMNIHLINVMVSSICIFY 190

Query: 172 VITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGG----LDRAT-----QIIASVDPN 222
            + GG  AVVWTDVVQ   MLL+++ + +L  +  GG    ++RA+          +DP 
Sbjct: 191 TMLGGIKAVVWTDVVQGAIMLLSVVAVGVLGTIRSGGMFTVMERASDGGRFNFDFGLDPR 250

Query: 223 KLHPFGGATGWAAIVFAIGYASWIVGYLG-QPHIVTRYMSVEDPRKLRRPGIFISGIWTT 281
               F GAT        +G      G++G     V R +S+      ++  + +SG+   
Sbjct: 251 IRMTFWGAT--------MGGIFMWTGHIGLNQSCVQRIVSLPSYSHAKK-SLIVSGLGFL 301

Query: 282 IVLWGAFFAGFLGFA-------LVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGI-I 333
           I+ +    +G + FA       ++A     V  P++++P   +  + G +AG  + G+ I
Sbjct: 302 IISFFNTISGIIMFARYYGCDPMLAG---LVSKPDKMMP-FFVQDIMGHLAG--MPGVFI 355

Query: 334 SAVMSTADSQLLVASSAIARDIY 356
           S V S A S L    +++A  +Y
Sbjct: 356 SCVFSAALSSLSATLNSLAGVVY 378


>gb|AAF57191.1| (AE003779) CG2196 gene product [Drosophila melanogaster]
           Length = 626
           
 Score = 73.7 bits (178), Expect = 5e-12
 Identities = 93/444 (20%), Positives = 188/444 (41%), Gaps = 45/444 (10%)

Query: 18  YIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAG 77
           Y G+++ K   T ++Y  GG+++  L   +S  +S  SG  M+  P   +  G       
Sbjct: 46  YFGFFS-KAKNTTEEYLQGGKRMPTLPVAISLVSSQLSGVAMMSVPAETYSFGFNM---- 100

Query: 78  IGCLFGTLADYLLIGPRLRIYAGKF---RAITLPDYLEARLKDNTK-LIRILSAAIILVF 133
              +F   A  L +   + I    F         +YLE R    T+ L+ I       + 
Sbjct: 101 ---IFVVWAMVLSVPVLIYIIVPVFYDNNVSNCYEYLELRFSKRTRQLVTITFILNQFLM 157

Query: 134 MTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLL 193
           +  Y+     A  +     +N+ +   ++ ++ +   Y + GG  AVVWTDVVQ   ML+
Sbjct: 158 LPVYMFVPSLAFSQV--TGYNIHLINTVVSSICVF--YTMLGGIKAVVWTDVVQGSVMLI 213

Query: 194 TLIIMPILALVEIGGLDRATQIIAS---VDPNKLHPFGGATGWAAIVFAIGYASWIVGYL 250
           +++++ IL     GG+    +  A     D  +++ F G      + F  G AS ++ + 
Sbjct: 214 SVVLVAILGTSNTGGITNVLENAAEGGRFDFRQVNGF-GIDPRLRLTFISGMASGLLMWT 272

Query: 251 GQ----PHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFAL------VAS 300
           G+       V R +S+      +R  + ++G+   +++    F G + FA       + +
Sbjct: 273 GKLGLDQSCVQRIVSLPSYGHAKR-CLLMAGVGFLLIMSFTCFTGIIMFAYYYGCDPIQA 331

Query: 301 GSIKVEDPERIVPAMAIHFLPGWVAGFVIAGI-ISAVMSTADSQLLVASSAIARDIYHKV 359
           G   V  P++++P   I  + G + G  + G+ IS V S + S L  + ++ A  +Y   
Sbjct: 332 G--LVSKPDKLMP-FFIQDIMGHMMG--MPGVFISCVFSASLSSLSASLNSFAGVVYFDY 386

Query: 360 LGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIY---QMVATAWGGLAVGFGPIL-- 414
           +   +   +    + + +  V + A  + I G  ++     ++ T W    +  G ++  
Sbjct: 387 IKPRINHSEAKANATMKLVIVVMGA--YCIVGGFIVQNFNSIIQTMWTITGINMGAVVGV 444

Query: 415 -TLSLWWKRVTKEAGIVGMAYGLI 437
             L ++  R   +  + G+A+  +
Sbjct: 445 FCLGMFVPRCNAKVAVSGIAFSCL 468


>gb|AAC12270.1| (AF026554) sodium-dependent multi-vitamin transporter [Rattus
           norvegicus] >gi|3746793|gb|AAC64060.1| (AF081204) sodium
           dependent multivitamin transporter [Rattus norvegicus]
           >gi|3746795|gb|AAC64061.1| (AF081205) sodium dependent
           multivitamin transporter [Rattus norvegicus]
           Length = 634
           
 Score = 71.8 bits (173), Expect = 2e-11
 Identities = 96/455 (21%), Positives = 170/455 (37%), Gaps = 43/455 (9%)

Query: 5   ILFGFLIYLVIL-----AYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLM 59
           ++FG L+ L ++     A  GW  +    T  +  +  RK+  L   LS  A+  S   +
Sbjct: 29  VVFGLLLVLSLVIGLYHACRGWGRH----TVGELLMADRKMGCLPVALSLLATFQSAVAI 84

Query: 60  LGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNT 119
           LG P   ++ G   ++ G     G L    +  P       +    +  +YLE R     
Sbjct: 85  LGGPAEIYRFGTQYWFLGCSYFLGLLIPAHIFIPVFY----RLHLTSAYEYLELRFN--- 137

Query: 120 KLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFA 179
           K +RI      +  M  Y+     A            +   +L   I+   Y   GG  A
Sbjct: 138 KAVRICGTVTFIFQMVVYMGVALYAPSLALNAVTGFDLWLSVLALGIVCNIYTALGGLKA 197

Query: 180 VVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIA--------SVDPNKLHPFGGAT 231
           V+WTDV Q + M L  +++ I+   ++GGL     + +         +DP+   PF   T
Sbjct: 198 VIWTDVFQTLIMFLGQLVVIIVGAAKVGGLGHVWAVASQHGLISGIELDPD---PFVRHT 254

Query: 232 GWAAIVFAIGYASWIVGYLGQPHI-VTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFA 290
            W     A G    ++   G     V RY+S     K      +       + L  +   
Sbjct: 255 FW---TLAFGGVFMMLSLYGVNQAQVQRYLS-SHSEKAAVLSCYAVFPCQQVALCMSCLI 310

Query: 291 GFLGFALVASGSIKVEDPERIVPAMAIHF-------LPGWVAGFVIAGIISAVMSTADSQ 343
           G + FA     S+  +  +     + ++F       +PG + G  +A + S  +ST  S 
Sbjct: 311 GLVMFAYYKKYSMSPQQEQAAPDQLVLYFVMDLLKDMPG-LPGLFVACLFSGSLSTISSA 369

Query: 344 LLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKV--IYQMVAT 401
               ++    D+      Q L + + + +SR +  A  LV +  A     +  + Q   +
Sbjct: 370 FNSLATVTMEDLIQPWFPQ-LTETRAIMLSRSLAFAYGLVCLGMAYVSSHLGSVLQAALS 428

Query: 402 AWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGL 436
            +G +      +  L +++        IVG+  GL
Sbjct: 429 IFGMVGGPLLGLFCLGMFFPCANPLGAIVGLLTGL 463


>gb|AAF52616.1| (AE003620) CG8451 gene product [Drosophila melanogaster]
           Length = 568
           
 Score = 71.8 bits (173), Expect = 2e-11
 Identities = 108/447 (24%), Positives = 186/447 (41%), Gaps = 63/447 (14%)

Query: 32  QYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLF-GTLADYLL 90
           +Y +G R + V    +S  AS  SG  +LG     +  G   ++  I  +  G    Y+ 
Sbjct: 64  EYLLGSRNLKVFPVAMSLIASYISGVTILGTTSEIYNYGTQYWFIAIAIMLQGIAVSYVY 123

Query: 91  IGPRLRIYAGKFRAITLPDYLEARLKDNTKLIR----ILSAAIILVFMTAYVAAQFAAGG 146
           I     +  G        +YLE R     + I     IL   + L F+  YV A      
Sbjct: 124 IPVFSALQVGSSY-----EYLEMRFHSVVRSIASFMFILDEILFLPFIV-YVPAI----- 172

Query: 147 KTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEI 206
               Q   +++    ++ V++   Y   GG  AVV TD  Q + M L+++ + ILA V  
Sbjct: 173 -ALNQVSGINLHVIAVVIVVVCVFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILATVYA 231

Query: 207 GGL----DRATQ----IIASVDPNKLHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTR 258
            GL    D A +    I  + +P+   P+   T W+ ++   G++ W         +V R
Sbjct: 232 NGLNVLFDDAAKGGRLIFNNTNPS---PYVRHTVWSVLIG--GFSYWTSFNAVNQTMVQR 286

Query: 259 YMSVEDPRKLRRP-GIFISGIWTTIVLWGAFFAGFLGFAL------VASGSIKVEDPERI 311
           YMS+   +K R    IF  G+   + +    + G L + +      +++G I  +D  ++
Sbjct: 287 YMSLPSLKKARASMAIFTIGVAAFVSV--CCYVGLLIYEMYKDCDPLSAGLITHDD--QL 342

Query: 312 VPAMAIHFLPG--WVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQM 369
           +P   +  +     ++G  IAGI  A +S+    L   S  I  DI       +  ++  
Sbjct: 343 LPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVRGCFKMQPSER-- 400

Query: 370 VNISRIVVAAVALVAMWFAITGPKVIYQM-----VATAWGGLAVG--FGPILTLSLWWKR 422
              S I+V +  +V  + A++   V+ Q+     + T+   +A G  FG + TL +    
Sbjct: 401 --ASTILVKSTVIVLGFVALSLVFVLEQLSGILSICTSMTAIAAGTTFG-LFTLGM---- 453

Query: 423 VTKEAGIVGMAYGLISEVILEAKIYGW 449
           +   A  VG A G I+  +L     GW
Sbjct: 454 LVPWANTVGTAVGGIASALLA----GW 476


>gb|AAK42292.1| Metabolite permease, putative [Sulfolobus solfataricus]
           Length = 526
           
 Score = 71.0 bits (171), Expect = 3e-11
 Identities = 113/507 (22%), Positives = 202/507 (39%), Gaps = 52/507 (10%)

Query: 9   FLIYLVILAYIGWWANKYTKTE----DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           F+I  VI  ++G++ +++ + +     ++ + GR++          A  ++ +  +  P 
Sbjct: 14  FIILFVIFVFLGFYGSRWRRGDLSKLHEWALAGRRLGPYLMWFLLTADLYTAYTFIAVPS 73

Query: 65  SAFKAGLGAFWAGIGCLFGTLADY--LLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLI 122
               +G   F+A     +  +  +  LL  PRL   A     +T  D+++ R   N++++
Sbjct: 74  LVLASGPVGFFAAF---YSAVTPFIALLFMPRLWTIAKNRGYVTAADFIKDRF--NSRIL 128

Query: 123 RILSAAIILVFMTAYVAAQFAA------------GGKTFAQAFNVSVTTGILITVIILTA 170
             L A   +V    Y+A Q               G      A ++S    +L+  IIL A
Sbjct: 129 AGLVAITGVVAELPYIALQIVGMQVALLILLLGLGVSNITLASDLS----LLVAFIILAA 184

Query: 171 YVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRA--------TQI-IASVDP 221
           +V T G      T V + + +L T+I + I   +  GG   A        +QI +A  + 
Sbjct: 185 FVFTSGLRGAALTAVYKDIIILGTIISIAIYVPLAFGGFSGAFHNAQTLSSQINLALNNV 244

Query: 222 NK-----LHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFIS 276
           NK       P   A   A I  AIG A  +  Y   PH V   +S  D +K  +  + + 
Sbjct: 245 NKPIFYNYLPNTLAARTAYISLAIGSAFALYLY---PHAVNASVS-SDSKKSLKLSLALQ 300

Query: 277 GIWTTIVLWGAFFAGFLGFA--LVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIIS 334
             ++ I+   A F G L +A   V +   K       VPA+  + +P W  G  + GI  
Sbjct: 301 PFYSIILAVIALF-GILVYANSKVVNFIAKTHSGAVAVPALIGYSMPDWFVGIALLGIFI 359

Query: 335 AVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKV 394
             +  A    + A++ + R+I  K     +       +++ +  A   +A+      P  
Sbjct: 360 GGLVPAAIMAIGAANLLTRNII-KEFKPNMSPSTESALAKWISTAFKFLALALVFATPST 418

Query: 395 IYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNP- 453
               +    G + +   P + L L+  ++   A + G A G+ S + L   +    F P 
Sbjct: 419 YAIQLQLLGGIIILQTLPSVFLGLYTSKLNGYALVGGWAGGMFSGIYL--TLLANHFGPL 476

Query: 454 KAPGFFGTLGQWFNGVPVFFINFFVTL 480
           K   F   LG  + GV    IN  + L
Sbjct: 477 KTSSFITPLGPMYIGVLSTLINLAIGL 503


>pir||S74025 conserved hypothetical protein c0207 - Sulfolobus solfataricus
           >gi|1707719|emb|CAA69485.1| (Y08256) orf c02007
           [Sulfolobus solfataricus]
           Length = 526
           
 Score = 71.0 bits (171), Expect = 3e-11
 Identities = 113/507 (22%), Positives = 202/507 (39%), Gaps = 52/507 (10%)

Query: 9   FLIYLVILAYIGWWANKYTKTE----DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64
           F+I  VI  ++G++ +++ + +     ++ + GR++          A  ++ +  +  P 
Sbjct: 14  FIILFVIFVFLGFYGSRWRRGDLSKLHEWALAGRRLGPYLMWFLLTADLYTAYTFIAVPS 73

Query: 65  SAFKAGLGAFWAGIGCLFGTLADY--LLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLI 122
               +G   F+A     +  +  +  LL  PRL   A     +T  D+++ R   N++++
Sbjct: 74  LVLASGPVGFFAAF---YSAVTPFIALLFMPRLWTIAKNRGYVTAADFIKDRF--NSRIL 128

Query: 123 RILSAAIILVFMTAYVAAQFAA------------GGKTFAQAFNVSVTTGILITVIILTA 170
             L A   +V    Y+A Q               G      A ++S    +L+  IIL A
Sbjct: 129 AGLVAITGVVAELPYIALQIVGMQVALLILLLGLGVSNITLASDLS----LLVAFIILAA 184

Query: 171 YVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRA--------TQI-IASVDP 221
           +V T G      T V + + +L T+I + I   +  GG   A        +QI +A  + 
Sbjct: 185 FVFTSGLRGAALTAVYKDIIILGTIISIAIYVPLAFGGFSGAFHNAQTLSSQINLALNNV 244

Query: 222 NK-----LHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFIS 276
           NK       P   A   A I  AIG A  +  Y   PH V   +S  D +K  +  + + 
Sbjct: 245 NKPIFYNYLPNTLAARTAYISLAIGSAFALYLY---PHAVNASVS-SDSKKSLKLSLALQ 300

Query: 277 GIWTTIVLWGAFFAGFLGFA--LVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIIS 334
             ++ I+   A F G L +A   V +   K       VPA+  + +P W  G  + GI  
Sbjct: 301 PFYSIILAVIALF-GILVYANSKVVNFIAKTHSGAVAVPALIGYSMPDWFVGIALLGIFI 359

Query: 335 AVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKV 394
             +  A    + A++ + R+I  K     +       +++ +  A   +A+      P  
Sbjct: 360 GGLVPAAIMAIGAANLLTRNII-KEFKPNMSPSTESALAKWISTAFKFLALALVFATPST 418

Query: 395 IYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNP- 453
               +    G + +   P + L L+  ++   A + G A G+ S + L   +    F P 
Sbjct: 419 YAIQLQLLGGIIILQTLPSVFLGLYTSKLNGYALVGGWAGGMFSGIYL--TLLANHFGPL 476

Query: 454 KAPGFFGTLGQWFNGVPVFFINFFVTL 480
           K   F   LG  + GV    IN  + L
Sbjct: 477 KTSSFITPLGPMYIGVLSTLINLAIGL 503


>emb|CAC11445.1| (AL445063) conserved hypothetical membrane protein [Thermoplasma
           acidophilum]
           Length = 495
           
 Score = 71.0 bits (171), Expect = 3e-11
 Identities = 97/505 (19%), Positives = 196/505 (38%), Gaps = 33/505 (6%)

Query: 11  IYLVILAYIGWWANKYTKTE----DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSA 66
           ++ V+   IG+ A  + +       ++ +GGR++          A  ++ +  +  P S 
Sbjct: 1   MFFVLFVLIGFLAKNFRRGNLNQLPEWALGGRRLGTFLVWFLVGADLYTAYTFIAVPSSM 60

Query: 67  FKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILS 126
           +  G   F+A +  +    A  ++  P+L   + K   +T  D++  R   N   + I  
Sbjct: 61  YAVGSIYFFA-VPYVSLAFAIAMITMPKLWTLSKKRGYVTAGDFVSDRFNSNALAMIIAL 119

Query: 127 AAII---------LVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGF 177
             I+         +V M A +       G     A N++    +++ +++L  +  T G 
Sbjct: 120 TGIVAELPYIALQIVGMRAILTGMLTPLGGNVDLASNIA----LVLAILVLIGFTYTSGL 175

Query: 178 FAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIV 237
                T V++   +  T+I++ +   V           +  V  +    F  A  W   +
Sbjct: 176 RGTSLTAVMKDAIIFTTVIVVIVTVFVAYHSALHEAFTVKPVYADLPPKFYNAY-WTLFL 234

Query: 238 FAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFAL 297
            +         YL  PH +   +S    +KLR     +  I+   + + A F   +    
Sbjct: 235 MSAAAL-----YL-YPHAINGSLSSMSAQKLRLSTALLP-IYGIGLAFLALFGVIIYGVP 287

Query: 298 VASGSIKV---EDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARD 354
            A   +K+    +   +VP +     P W  GF   GI    +  A    +  ++ + R+
Sbjct: 288 AAEHVLKITYANNGAMVVPTLIATVTPSWFTGFAFLGIFIGGLVPAAIMSMSQATLLTRN 347

Query: 355 IYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPIL 414
           +  K LG+EL +K+   I+++ +    L+A+ F    P+     +    G + +   P +
Sbjct: 348 VI-KYLGRELEEKRETFIAKVSMIFFQLLALAFVFIVPETYSISLQLIGGIIILQTLPAV 406

Query: 415 TLSLWWKRVTKEAGIVGMAYGLISEVILEAK---IYGWAFNPKAPGFFGTLGQWFNGVPV 471
            L ++ KR+ K A   G   G+++ +  E     +Y      K      +LG  F G   
Sbjct: 407 FLGMYVKRLEKYAVAAGWLAGIVAGIYFEVYSNFVYFKYSIIKTTLMPSSLGFIFVGFTA 466

Query: 472 FFINFFVTLFIIIIVSLLTKPPEDV 496
             IN  V   +  +V  L + P+++
Sbjct: 467 LVINLIVVGVVEAVVYALHRQPKNL 491


>gb|AAF46260.1| (AE003440) CG9657 gene product [Drosophila melanogaster]
           Length = 653
           
 Score = 69.5 bits (167), Expect = 9e-11
 Identities = 73/283 (25%), Positives = 121/283 (41%), Gaps = 31/283 (10%)

Query: 150 AQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGG- 208
           A   N+ + T I+  V I   Y   GG  AVVWTDV+Q + M   + ++ I   ++IGG 
Sbjct: 177 ATGVNIHIVTPIVCVVCIF--YTCIGGLKAVVWTDVIQTLIMFGAMALVLIKGTLDIGGP 234

Query: 209 ---LDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDP 265
                +A +      PN          + ++V   G A W+       +++ RY+S+   
Sbjct: 235 GVVWQKAQETARLEVPNFSADLSERYTFYSLVLG-GVAHWLKSNAISQNMIQRYLSLPTL 293

Query: 266 RKLRRPGIFISGIWTTI--VLWGAFFAGFLGFALVASGS-------IKVEDPERIVPAMA 316
           R  R        IWT I  VL      G+ G  + A+ S          +  ++++P + 
Sbjct: 294 RDAR------IAIWTFIAGVLAFLMICGYTGLLIYATYSQCDPLETKLAQRNDQLLPLLV 347

Query: 317 IHFL---PGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQEL--GKKQMVN 371
           +  L   PG + G  +AG+ SA +S+  + L   S+ +  D         L  G+   V 
Sbjct: 348 MDTLGSYPG-LPGVFVAGVFSAALSSLSTGLNSLSAVVLEDFVKTFRKSPLTEGQTAFVM 406

Query: 372 ISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPIL 414
            S +VV  +  VA+ FA+     + Q+  T     +V  GP+L
Sbjct: 407 RSVVVVFGIIFVALVFAVEKLGAVLQLTITL---SSVANGPLL 446


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.328    0.143    0.442 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 194141123
Number of Sequences: 2977
Number of extensions: 8097242
Number of successful extensions: 29718
Number of sequences better than 1.0e-10: 116
Number of HSP's better than  0.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 63
Number of HSP's that attempted gapping in prelim test: 29297
Number of HSP's gapped (non-prelim): 133
length of query: 537
length of database: 189,106,746
effective HSP length: 52
effective length of query: 485
effective length of database: 157,985,422
effective search space: 76622929670
effective search space used: 76622929670
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.7 bits)
S2: 167 (69.5 bits)