BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1841 (putP-2) DE:proline permease (putP-2) (537 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||A75123 proline permease (putp-2) PAB1841 - Pyrococcus abyss... 1075 0.0 pir||C71008 probable proline permease - Pyrococcus horikoshii >g... 1008 0.0 pir||D75188 proline symporter (proline permease). PAB2354 - Pyro... 360 2e-98 pir||H82382 sodium/proline symporter VCA1071 [imported] - Vibrio... 323 4e-87 pir||T44298 proline transporter [imported] - Bacillus halodurans... 321 2e-86 sp|O06493|OPUE_BACSU OSMOREGULATED PROLINE TRANSPORTER (SODIUM/P... 304 1e-81 pir||B81297 sodium/proline symporter Cj1502c [imported] - Campyl... 303 2e-81 dbj|BAB06425.1| (AP001516) proline transporter [Bacillus halodur... 300 4e-80 pir||G64526 sodium/proline symporter - Helicobacter pylori (stra... 299 6e-80 pir||A71980 sodium/proline symporter - Helicobacter pylori (stra... 298 1e-79 pir||T48676 proline uptake protein [validated] - Staphylococcus ... 292 6e-78 gb|AAA79365.1| (U06451) proline permease homolog [Staphylococcus... 292 8e-78 pir||F83547 sodium/proline symporter PutP PA0783 [imported] - Ps... 291 2e-77 gb|AAA99282.1| (L01140) proline permease [Salmonella sp.] >gi|15... 290 3e-77 gb|AAA24465.1| (L01152) proline permease [Escherichia coli] 289 7e-77 gb|AAA24461.1| (L01132) proline permease [Escherichia coli] >gi|... 288 1e-76 gb|AAA99281.1| (L01139) proline permease [Salmonella sp.] 287 2e-76 gb|AAA99284.1| (L01142) proline permease [Salmonella sp.] >gi|15... 287 2e-76 gb|AAA99286.1| (L01144) proline permease [Salmonella sp.] >gi|15... 287 2e-76 sp|P10502|PUTP_SALTY SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)... 287 2e-76 gb|AAA27199.1| (L01135) proline permease [Salmonella typhimurium] 287 2e-76 gb|AAA26389.1| (L01134) proline permease [Rickettsia typhi] 287 2e-76 gb|AAA24466.1| (L01153) proline permease [Escherichia coli] >gi|... 287 2e-76 sp|P07117|PUTP_ECOLI SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)... 287 3e-76 gb|AAA24463.1| (L01150) proline permease [Escherichia coli] >gi|... 287 3e-76 gb|AAA99278.1| (L01136) proline permease [Salmonella sp.] 287 3e-76 gb|AAA24462.1| (L01133) proline permease [Escherichia coli] 287 3e-76 gb|AAA99279.1| (L01137) proline permease [Salmonella sp.] 287 3e-76 gb|AAA99280.1| (L01138) proline permease [Salmonella sp.] 287 3e-76 gb|AAA24468.1| (L01155) proline permease [Escherichia coli] 286 3e-76 pir||JC2382 sodium/proline symporter - Pseudomonas fluorescens >... 286 5e-76 gb|AAA99288.1| (L01146) proline permease [Salmonella sp.] >gi|15... 286 5e-76 gb|AAA99291.1| (L01149) proline permease [Salmonella sp.] 286 6e-76 pir||S10220 sodium/proline symporter - Salmonella typhimurium 284 1e-75 gb|AAA99290.1| (L01148) proline permease [Salmonella sp.] 284 2e-75 pir||G81202 sodium/proline symporter NMB0402 [imported] - Neisse... 280 3e-74 gb|AAF25001.1|AF153207_2 (AF153207) proline permease [Pseudomona... 278 1e-73 pir||B69759 sodium/proline symporter ycgO - Bacillus subtilis >g... 277 2e-73 gb|AAG19342.1| (AE005029) proline permease; PutP [Halobacterium ... 277 3e-73 sp|P45174|PUTP_HAEIN SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)... 275 7e-73 emb|CAA70363.1| (Y09163) proline transport system [Corynebacteri... 266 4e-70 pir||E75138 osmoregulated proline transporter PAB0609 - Pyrococc... 255 1e-66 pir||C69115 sodium/proline symporter (proline permease) - Methan... 191 1e-47 pir||D65118 pantothenate permease [validated] - Escherichia coli... 184 2e-45 sp|P16256|PANF_ECOLI SODIUM/PANTOTHENATE SYMPORTER (PANTOTHENATE... 184 2e-45 sp|P44963|PANF_HAEIN SODIUM/PANTOTHENATE SYMPORTER (PANTOTHENATE... 180 4e-44 gb|AAF45263.1| (AF230602) proline permease [Escherichia coli] >g... 171 2e-41 gb|AAF45280.1| (AF230619) proline permease [Escherichia coli] 171 2e-41 gb|AAF45283.1| (AF230622) proline permease [Escherichia coli] 171 2e-41 gb|AAF45285.1| (AF230624) proline permease [Escherichia coli] 171 2e-41 gb|AAF45264.1| (AF230603) proline permease [Escherichia coli] >g... 170 4e-41 gb|AAF45286.1| (AF230625) proline permease [Escherichia coli] 168 1e-40 gi|11497636 proline permease (putP-1) [Archaeoglobus fulgidus] >... 163 4e-39 pir||JU0296 pantothenate permease - Escherichia coli >gi|147067|... 153 3e-36 pir||E70201 pantothenate permease (panF) homolog - Lyme disease ... 142 1e-32 dbj|BAB07462.1| (AP001519) Na+/solute symporter (Ssf family) [Ba... 141 1e-32 gi|11498674 pantothenate permease (panF-1) [Archaeoglobus fulgid... 139 7e-32 pir||F83241 probable sodium:solute symporter PA3234 [imported] -... 138 1e-31 gi|11498821 proline permease (putP-3) [Archaeoglobus fulgidus] >... 138 2e-31 gi|11498574 proline permease (putP-2) [Archaeoglobus fulgidus] >... 137 4e-31 pir||H71097 hypothetical protein PH1044 - Pyrococcus horikoshii ... 134 2e-30 sp|P32705|YJCG_ECOLI HYPOTHETICAL 59.2 KD PROTEIN IN SOXR-ACS IN... 134 2e-30 pir||E70480 probable sodium/proline symporter ssf [similarity] -... 134 2e-30 gb|AAG20007.1| (AE005081) pantothenate permease; PanF [Halobacte... 128 1e-28 pir||E82043 probable sodium/solute symporter VC2705 [imported] -... 124 2e-27 pir||S52839 dhlC protein - Xanthobacter autotrophicus >gi|763398... 124 3e-27 sp|P39599|YWCA_BACSU HYPOTHETICAL 55.0 KD PROTEIN IN EPR-GALK IN... 122 1e-26 gi|11497853 pantothenate permease (panF-3) [Archaeoglobus fulgid... 118 1e-25 pir||C82582 Na+-dependent symport homolog XF2251 [imported] - Xy... 116 5e-25 emb|CAA94864.1| (Z71176) phenylacetic acid permease [Pseudomonas... 113 4e-24 sp|P96169|SGLT_VIBPA SODIUM/GLUCOSE COTRANSPORTER (NA(+)/GLUCOSE... 109 8e-23 dbj|BAA11215.1| (D78137) Na+/glucose symporter [Vibrio parahaemo... 109 1e-22 pir||S75887 hypothetical protein - Synechocystis sp. (strain PCC... 108 1e-22 pir||E83468 probable sodium:solute symport protein PA1418 [impor... 106 5e-22 pir||B69833 metabolite permease homolog yhjB - Bacillus subtilis... 105 1e-21 pir||H75513 probable sodium/proline symporter DR0477 [similarity... 105 1e-21 gb|AAF54633.1| (AE003691) CG6723 gene product [Drosophila melano... 105 2e-21 emb|CAB59438.1| (AL132644) putative transmembrane transport prot... 104 2e-21 pir||T03475 transmembrane protein - Rhodobacter capsulatus >gi|3... 104 3e-21 dbj|BAB05941.1| (AP001514) Na+/myo-inositol cotransporter [Bacil... 101 2e-20 pir||C69903 proline permease homolog yodF - Bacillus subtilis >g... 100 4e-20 emb|CAC17810.1| (AJ276242) sodium iodide symporter [Sus scrofa] 99 9e-20 emb|CAC17816.1| (AJ276292) sodium iodide symporter [Sus scrofa] 99 9e-20 gb|AAB81169.1| (AF006665) YolC [Bacillus subtilis] 99 1e-19 pir||T35201 probable transmembrane transport - Streptomyces coel... 99 1e-19 gb|AAG01741.1|AF251267_1 (AF251267) low affinity sodium-glucose ... 95 2e-18 pir||E72071 hypothetical proline permease - Chlamydophila pneumo... 95 2e-18 gb|AAF73651.1| (AE002186) sodium:solute symporter family protein... 95 2e-18 emb|CAB95932.1| (AL359989) putative sodium:solute symporter [Str... 94 5e-18 gi|6981552 solute carrier family 5, member alpha 1 (Na+/glucose ... 93 7e-18 dbj|BAA19172.1| (AB000729) Na/glucose cotransporter [Rattus norv... 93 7e-18 gi|4507035 solute carrier family 5 (sodium iodide symporter), me... 92 1e-17 dbj|BAA24835.1| (D87920) sodium iodide symporter [Homo sapiens] 92 1e-17 emb|CAC00574.1| (AL109659) dJ1024N4.1 (novel Sodium:solute sympo... 92 2e-17 pir||D72694 hypothetical protein APE0972 - Aeropyrum pernix (str... 90 6e-17 emb|CAB94614.1| (AL359214) putative permease [Streptomyces coeli... 90 8e-17 gi|11498804 pantothenate permease (panF-2) [Archaeoglobus fulgid... 89 1e-16 pir||S68513 thyroid iodide transport protein - rat >gi|1399954|g... 87 4e-16 pir||G83610 probable sodium:solute symporter PA0287 [imported] -... 87 4e-16 sp|P23723|PUTP_KLEPN SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE)... 85 3e-15 prf||2204393A Na/I symporter [Rattus norvegicus] 84 4e-15 emb|CAC16517.1| (AL450223) putative integral membrane transport ... 83 6e-15 gb|AAK42614.1| Metabolite permease, putative [Sulfolobus solfata... 82 1e-14 gb|AAA66065.1| (U08813) 597 aa protein related to Na/glucose cot... 82 2e-14 pir||A82432 sodium/solute symporter VCA0667 [imported] - Vibrio ... 81 3e-14 pir||T28017 hypothetical protein ZK822.5 - Caenorhabditis elegan... 80 8e-14 pir||T32478 hypothetical protein F52H2.4 - Caenorhabditis elegan... 78 2e-13 emb|CAB88444.1| (AL353815) putative sodium-coupled permease [Str... 76 1e-12 gb|AAB39701.1| (U72716) unknown [Drosophila melanogaster] >gi|73... 75 2e-12 gb|AAF57191.1| (AE003779) CG2196 gene product [Drosophila melano... 74 5e-12 gb|AAC12270.1| (AF026554) sodium-dependent multi-vitamin transpo... 72 2e-11 gb|AAF52616.1| (AE003620) CG8451 gene product [Drosophila melano... 72 2e-11 gb|AAK42292.1| Metabolite permease, putative [Sulfolobus solfata... 71 3e-11 pir||S74025 conserved hypothetical protein c0207 - Sulfolobus so... 71 3e-11 emb|CAC11445.1| (AL445063) conserved hypothetical membrane prote... 71 3e-11 gb|AAF46260.1| (AE003440) CG9657 gene product [Drosophila melano... 69 9e-11 >pir||A75123 proline permease (putp-2) PAB1841 - Pyrococcus abyssi (strain Orsay) >gi|5458209|emb|CAB49698.1| (AJ248285) proline permease (putP-2) [Pyrococcus abyssi] Length = 537 Score = 1075 bits (2749), Expect = 0.0 Identities = 537/537 (100%), Positives = 537/537 (100%) Query: 1 MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60 MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML Sbjct: 1 MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60 Query: 61 GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTK 120 GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTK Sbjct: 61 GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTK 120 Query: 121 LIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAV 180 LIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAV Sbjct: 121 LIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAV 180 Query: 181 VWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAI 240 VWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAI Sbjct: 181 VWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAI 240 Query: 241 GYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVAS 300 GYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVAS Sbjct: 241 GYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVAS 300 Query: 301 GSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVL 360 GSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVL Sbjct: 301 GSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVL 360 Query: 361 GQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWW 420 GQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWW Sbjct: 361 GQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWW 420 Query: 421 KRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTL 480 KRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTL Sbjct: 421 KRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTL 480 Query: 481 FIIIIVSLLTKPPEDVVKLHEELFKKVPIEKSEKIKTARMKSQAENVFDFAVSSGLL 537 FIIIIVSLLTKPPEDVVKLHEELFKKVPIEKSEKIKTARMKSQAENVFDFAVSSGLL Sbjct: 481 FIIIIVSLLTKPPEDVVKLHEELFKKVPIEKSEKIKTARMKSQAENVFDFAVSSGLL 537 >pir||C71008 probable proline permease - Pyrococcus horikoshii >gi|3257784|dbj|BAA30467.1| (AP000006) 537aa long hypothetical proline permease [Pyrococcus horikoshii] Length = 537 Score = 1008 bits (2577), Expect = 0.0 Identities = 490/537 (91%), Positives = 519/537 (96%) Query: 1 MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60 MN GIL GFLIYLV+LAYIGWWAN+YTKTE+QYF+GGRKVHVLAATLSDKASDFSGWLML Sbjct: 1 MNLGILLGFLIYLVLLAYIGWWANRYTKTEEQYFIGGRKVHVLAATLSDKASDFSGWLML 60 Query: 61 GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTK 120 GYPG+AFK GLGAFWA IGCLFGTLADYLLIGPRLRIYAGKFR+ITLPDYLEARLKDNTK Sbjct: 61 GYPGTAFKTGLGAFWAAIGCLFGTLADYLLIGPRLRIYAGKFRSITLPDYLEARLKDNTK 120 Query: 121 LIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAV 180 LIRILSAAIIL+FMTAYVAAQFAAGGKTF++AF VSVTTGILITVIILTAYVITGGFFAV Sbjct: 121 LIRILSAAIILIFMTAYVAAQFAAGGKTFSEAFGVSVTTGILITVIILTAYVITGGFFAV 180 Query: 181 VWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAI 240 VWTDVVQAMFMLLTLIIMPILAL EIGGLD+ATQII SV+P KLHPFGGATG AAIVFAI Sbjct: 181 VWTDVVQAMFMLLTLIIMPILALAEIGGLDKATQIIGSVNPAKLHPFGGATGLAAIVFAI 240 Query: 241 GYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVAS 300 GYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFAL + Sbjct: 241 GYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALAIN 300 Query: 301 GSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVL 360 GSIK++DPE+IVPAMA+HFLP W+AGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVL Sbjct: 301 GSIKIDDPEKIVPAMAVHFLPSWIAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVL 360 Query: 361 GQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWW 420 GQELGKKQMVNISR+VVA V+L+AMWFAI+GPKVIYQMVATAWGGLAVGFGPILTLSLWW Sbjct: 361 GQELGKKQMVNISRVVVAIVSLIAMWFAISGPKVIYQMVATAWGGLAVGFGPILTLSLWW 420 Query: 421 KRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTL 480 KRVTKEAGI+GM YGLISEV+LEAKIYGWAFNP APGFFGTLG+WFNGVPVFFINFF+TL Sbjct: 421 KRVTKEAGIIGMGYGLISEVLLEAKIYGWAFNPNAPGFFGTLGKWFNGVPVFFINFFITL 480 Query: 481 FIIIIVSLLTKPPEDVVKLHEELFKKVPIEKSEKIKTARMKSQAENVFDFAVSSGLL 537 +IIIVSLLTKPPEDVVKLH+ELFKKVPIEKSEKIK AR KSQAENVFDFA++SGLL Sbjct: 481 LVIIIVSLLTKPPEDVVKLHKELFKKVPIEKSEKIKVARAKSQAENVFDFAIASGLL 537 >pir||D75188 proline symporter (proline permease). PAB2354 - Pyrococcus abyssi (strain Orsay) >gi|5457464|emb|CAB48955.1| (AJ248283) PROLINE SYMPORTER (PROLINE PERMEASE). [Pyrococcus abyssi] Length = 492 Score = 360 bits (914), Expect = 2e-98 Identities = 186/503 (36%), Positives = 299/503 (58%), Gaps = 30/503 (5%) Query: 6 LFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65 L FL L++ +G++A K TK+E+ +FVGGR + + LS +S S WL+LG G Sbjct: 14 LVAFLFTLILPILVGFYAMKRTKSEEDFFVGGRAMDKITVALSAVSSGRSSWLVLGLSGM 73 Query: 66 AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRIL 125 A+K G+ A WA +G + + ++ +G RLR ++ +F AIT+PDY EAR +D +K++RI Sbjct: 74 AYKMGVTAVWAAVGYIVAEMFQFVYMGIRLRKFSERFNAITVPDYFEARFRDTSKILRIA 133 Query: 126 SAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDV 185 ++ II++F+T+YV AQF AG KT + A +S+ T ++I+V+++ Y+I GGF AV + DV Sbjct: 134 ASIIIIIFLTSYVGAQFNAGAKTLSTALGISIFTALMISVLMIIVYMILGGFIAVAYNDV 193 Query: 186 VQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASW 245 ++A+ M++ L+++P++A+ ++GG + +++ ++DP ++P+ G IG+ Sbjct: 194 IRAVIMIIGLVVLPVIAVAKVGGTEEVLKVLHALDPKLINPWAFGAGVVIGFLGIGF--- 250 Query: 246 IVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVASGS-IK 304 G GQPHI+ RYMS++DP KLR + + W ++ WGA F G G A+V S + Sbjct: 251 --GSPGQPHIIVRYMSIDDPNKLRVSTV-VGTFWNVVLAWGAIFVGLAGRAIVPDVSQLP 307 Query: 305 VEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVL--GQ 362 ++ E I P ++ + P + G +I GI +A++STADSQLLV +S + +D+Y +V+ G Sbjct: 308 GKNAEMIYPYLSAQYFPPILYGILIGGIFAAILSTADSQLLVVASTVVKDLYQEVIKKGT 367 Query: 363 ELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWKR 422 ++ +K + ISR+ V V +A A +I+ V AWGGL FGP L LSL+WK Sbjct: 368 KIDEKTALTISRVTVLVVGFLAAILAYVAKDIIFWFVLFAWGGLGASFGPTLILSLYWKG 427 Query: 423 VTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTLFI 482 TK + GM G I+ ++ W + + + VP F + T Sbjct: 428 TTKWGVLAGMIVGTITTIV-------WKL------YLKPITGLYELVPAFIFSLIAT--- 471 Query: 483 IIIVSLLTKPPEDVVKLHEELFK 505 IIVS++TKPPE+V EEL K Sbjct: 472 -IIVSMITKPPENV----EELMK 489 >pir||H82382 sodium/proline symporter VCA1071 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9658517|gb|AAF96965.1| (AE004432) sodium/proline symporter [Vibrio cholerae] Length = 496 Score = 323 bits (818), Expect = 4e-87 Identities = 184/514 (35%), Positives = 284/514 (54%), Gaps = 28/514 (5%) Query: 2 NFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLG 61 +F I F++YL+++ IG +A + TK YF+GGR + A LS ASD SGWL+LG Sbjct: 4 SFAITTTFIVYLILMLAIGVYAYQRTKNSADYFLGGRSLGPWPAALSAGASDMSGWLLLG 63 Query: 62 YPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKL 121 PG A+ AG+ +FW G L GT A++L+ RLR Y+ ++TLP++L R DN+KL Sbjct: 64 LPGYAYAAGIESFWLAGGLLVGTWANWLVNAKRLRTYSITTDSLTLPEFLSRRFNDNSKL 123 Query: 122 IRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVV 181 I+ +SA IL+F Y ++ AGGK F F + +T ++I + + +Y + GGF AV Sbjct: 124 IQTISAFFILLFFLFYTSSGLVAGGKLFETVFGLDYSTAVIIGTVCVVSYTLFGGFLAVS 183 Query: 182 WTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFA-I 240 WTD+VQ + M L+I+PI A+ GG + +A+++P L + A G A I Sbjct: 184 WTDLVQGLLMAAALMIVPIAAM--NGGFTQLNHDLAAINPELLTLWNDAKGEPLSAIAII 241 Query: 241 GYASWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL 297 +W +GY GQPHI+ R+ + + L RR I+ +WT + + GA G G Sbjct: 242 SLVAWGLGYFGQPHILARFKASRSNKDLITARR----IAVVWTGLSMAGAILVGLTGLIF 297 Query: 298 VA-SGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIY 356 V SG+I ++D E+I + +AG ++A I++A+MSTADSQLLV+SSA+A D Y Sbjct: 298 VTQSGTIGLDDGEKIFMLLVNSLFHPVIAGILLAAILAAIMSTADSQLLVSSSALAEDFY 357 Query: 357 HKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTL 416 +V + + +V + RI V ++L+A++ A+T + +V+ AW G FGP L L Sbjct: 358 KQVFKTDASSEDIVRVGRIAVILISLIALFLAMTPDSSVLGLVSYAWAGFGAAFGPALVL 417 Query: 417 SLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINF 476 SL+W R+ + + G+ G ++ V+ + GW + VP Sbjct: 418 SLYWPRMNRHGALSGIIVGGVTIVVWKQLSGGWF-------------DVYEIVP----GI 460 Query: 477 FVTLFIIIIVSLLTKPPEDVVKLHEELFKKVPIE 510 ++ I++VSLLT P++ VK FKK IE Sbjct: 461 ILSTLSIVVVSLLTGEPDEKVKAQHATFKKQLIE 494 >pir||T44298 proline transporter [imported] - Bacillus halodurans >gi|4512352|dbj|BAA75317.1| (AB011836) proline transporter [Bacillus halodurans] >gi|10173274|dbj|BAB04379.1| (AP001509) sodium/proline symporter [Bacillus halodurans] Length = 501 Score = 321 bits (813), Expect = 2e-86 Identities = 185/512 (36%), Positives = 280/512 (54%), Gaps = 17/512 (3%) Query: 1 MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60 M L F++YLV + IG A + T Y +GGR++ A LS ASD S WL+L Sbjct: 1 MELATLITFIVYLVGMLVIGLIAYRMTNNLSDYVLGGRRLGGSVAALSAGASDMSSWLLL 60 Query: 61 GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFR-AITLPDYLEARLKDNT 119 G PG+ + G+G W +G G ++ + RLR Y + +ITLPD+LE R D + Sbjct: 61 GLPGALYVGGMGEIWIAVGLAIGAYLNWQFLAARLRNYTEIAKDSITLPDFLENRFHDKS 120 Query: 120 KLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFA 179 K++RI+SA +ILVF T Y +A G F +F ++ + I I++ +Y GGF A Sbjct: 121 KILRIVSALVILVFFTFYTSAGLVGGALLFEASFGMTYIQALWIGAIVIISYTFLGGFLA 180 Query: 180 VVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFA 239 V WTD Q + M L LII+PI+A+ ++GG + ++D L F GAT ++ Sbjct: 181 VSWTDFFQGILMFLALIIVPIVAINKMGGFSETLNAVGAIDTAYLDAFQGAT----VIGV 236 Query: 240 IGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVA 299 +W +GY GQPHIVTR+M+V+ +++ + FI W + L+GA F GF+G A + Sbjct: 237 ASLLAWGLGYFGQPHIVTRFMAVKSLKEIPKAR-FIGMTWMVLALFGAIFTGFVGIAYFS 295 Query: 300 SGS----IKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 + I E E + WVAGF++A I+SA+MST DSQLLV+SSA+A D Sbjct: 296 ATGPGPEIAGEARETVFILFTQILFDPWVAGFLLAAILSAIMSTIDSQLLVSSSALAEDF 355 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y +L + +K++V + R V +ALVA+ A + +V AW G FGP+L Sbjct: 356 YKGMLRKNASQKELVWVGRFGVVLIALVAIVLAYNPDSTVLDLVGYAWAGFGAAFGPVLL 415 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFIN 475 LSL+WKR+T+ + GM G + VI+ A++ W FN + LG + +P F + Sbjct: 416 LSLFWKRMTRNGALAGMVVG-GATVIIWAELTNW-FNLSVEQ-YPILG-LYEIIPGFIL- 470 Query: 476 FFVTLFIIIIVSLLTKPPEDVVKLHEELFKKV 507 ++ II++ L +PP+++ E+ KV Sbjct: 471 --ASIAIIVVSRLDQEPPQEIQDEFEKAKTKV 500 >sp|O06493|OPUE_BACSU OSMOREGULATED PROLINE TRANSPORTER (SODIUM/PROLINE SYMPORTER) >gi|7442757|pir||H69670 sodium/proline symporter opuE - Bacillus subtilis >gi|2114423|gb|AAB66512.1| (U92466) osmoregulated proline transporter [Bacillus subtilis] >gi|2465556|gb|AAB72182.1| (AF011545) OpuE [Bacillus subtilis] >gi|2632980|emb|CAB12486.1| (Z99107) proline transporter [Bacillus subtilis] Length = 492 Score = 304 bits (771), Expect = 1e-81 Identities = 162/494 (32%), Positives = 261/494 (52%), Gaps = 22/494 (4%) Query: 1 MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60 M+ I+ IY + + IGW+A K T + Y +GGR + LS A+D SGW+++ Sbjct: 1 MSIEIIISLGIYFIAMLLIGWYAFKKTTDINDYMLGGRGLGPFVTALSAGAADMSGWMLM 60 Query: 61 GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYA-GKFRAITLPDYLEARLKDNT 119 G PG+ F GL W +G G ++YLL+ PRLR Y AIT+PD+ + R + ++ Sbjct: 61 GVPGAMFATGLSTLWLALGLTIGAYSNYLLLAPRLRAYTEAADDAITIPDFFDKRFQHSS 120 Query: 120 KLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFA 179 L++I+SA II++F T Y ++ +GG+ F AF G+ +T ++ Y + GGF A Sbjct: 121 SLLKIVSALIIMIFFTLYTSSGMVSGGRLFESAFGADYKLGLFLTTAVVVLYTLFGGFLA 180 Query: 180 VVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFA 239 V TD VQ M L+++PI+A +GG+ I +V+P+ L F G A+++ Sbjct: 181 VSLTDFVQGAIMFAALVLVPIVAFTHVGGVAPTFHEIDAVNPHLLDIFKG----ASVISI 236 Query: 240 IGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVA 299 I Y +W +GY GQPHI+ R+M+++D + L +P I W I + G+ G +G A Sbjct: 237 ISYLAWGLGYYGQPHIIVRFMAIKDIKDL-KPARRIGMSWMIITVLGSVLTGLIGVAYAH 295 Query: 300 SGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKV 359 + V+DPE I + + GF+++ I++A+MS+ SQLLV +SA+ D+Y Sbjct: 296 KFGVAVKDPEMIFIIFSKILFHPLITGFLLSAILAAIMSSISSQLLVTASAVTEDLYRSF 355 Query: 360 LGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLW 419 ++ K++V I R+ V +A++A+ ++ I +V AW G FGP + LSL+ Sbjct: 356 FRRKASDKELVMIGRLSVLVIAVIAVLLSLNPNSTILDLVGYAWAGFGSAFGPAILLSLY 415 Query: 420 WKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVT 479 WKR+ + + M G + +I W A GV F ++ Sbjct: 416 WKRMNEWGALAAMIVGAATVLI-------WITTGLAKS---------TGVYEIIPGFILS 459 Query: 480 LFIIIIVSLLTKPP 493 + IIVS++TK P Sbjct: 460 MIAGIIVSMITKRP 473 >pir||B81297 sodium/proline symporter Cj1502c [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968927|emb|CAB73923.1| (AL139078) sodium/proline symporter [Campylobacter jejuni] Length = 495 Score = 303 bits (769), Expect = 2e-81 Identities = 164/507 (32%), Positives = 265/507 (51%), Gaps = 25/507 (4%) Query: 1 MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60 +N I F++Y +++ YIG++ K K + YF+GGR + + + LS ASD SGWL++ Sbjct: 12 INTPIAVMFVVYALLMLYIGFYFYKQNKNSEDYFLGGRTMGPVISALSAGASDMSGWLLM 71 Query: 61 GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKF-RAITLPDYLEARLKDNT 119 G PG+ + +G + IG G +++ + RLRIY ++T+PDY E R D+ Sbjct: 72 GLPGALYVSGFIDSYIAIGLTIGASLNWIFVAKRLRIYTSVIANSLTIPDYFETRFDDDK 131 Query: 120 KLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFA 179 ++RI+ A +IL+F T YV++ +G K F F + + II+ AY GG+ A Sbjct: 132 HILRIVCAVVILIFFTFYVSSGLVSGAKLFESTFGIRYDYALTTGTIIIVAYTFLGGYKA 191 Query: 180 VVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFA 239 V WTD++Q + M++ LII+P++ L +GG A I+ + P L G G +I+ A Sbjct: 192 VCWTDMIQGLLMMMALIIVPLVMLYHLGGFGEAMNIVREIKPQALS-MGEGVGIVSIISA 250 Query: 240 IGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVA 299 + +W +GY GQPHI+ R+MS+ + + FI W + L A G LG A V Sbjct: 251 L---AWGLGYFGQPHILVRFMSIRSTKDIPM-ATFIGIAWMAVCLLSACMIGILGIAYVH 306 Query: 300 SGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKV 359 + ++DPE+I M+ W+AG +++ I++A+MSTA SQLLV+SS IA D Y K+ Sbjct: 307 KFELSLQDPEKIFIVMSQLLFNPWIAGILLSAILAAIMSTASSQLLVSSSTIAEDFYKKI 366 Query: 360 LGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLW 419 ++ ++N+ ++ V VA++A + + +V+ AW G FG ++ SL+ Sbjct: 367 FREDAPSHIVLNLGKLGVLLVAVIAFLISTDKNSSVLSIVSYAWAGFGASFGSVMLFSLF 426 Query: 420 WKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVT 479 W R+T+ I+GM G + V+L PG F V Sbjct: 427 WSRMTRVGAILGMITG-AATVVLWKNFANSGLYEIVPG------------------FLVA 467 Query: 480 LFIIIIVSLLTKPPEDVVKLHEELFKK 506 +III SL T +E++ K+ Sbjct: 468 SVVIIIASLFTNVRSGTKAAYEKMLKE 494 >dbj|BAB06425.1| (AP001516) proline transporter [Bacillus halodurans] Length = 507 Score = 300 bits (759), Expect = 4e-80 Identities = 178/501 (35%), Positives = 282/501 (55%), Gaps = 17/501 (3%) Query: 10 LIYLVILAYIGWWANKYTKTE-DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFK 68 + YLV L IG ++K + +F+ GR ++ LS +S S WL+LG G+A+ Sbjct: 13 IAYLVALLLIGLLSSKKSSVGMTDFFIAGRNLNKWTVALSAVSSGRSAWLVLGVTGTAYA 72 Query: 69 AGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAA 128 GL A WA G + + + + R R Y+ + +IT+PD LE R D T ++R SA Sbjct: 73 TGLDAVWAVAGYITVEVFLFFYVARRFRAYSEQTGSITIPDILETRFNDKTHILRGGSAF 132 Query: 129 IILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQA 188 II+ FM AYVA+Q AGG FA + VS +TG+ +T +IL AY + GGF AV TDVVQA Sbjct: 133 IIMFFMIAYVASQLVAGGGAFATSMGVSSSTGMWVTAVILLAYTMLGGFHAVSKTDVVQA 192 Query: 189 MFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIVG 248 FM ++L+I+P++A++ +GG D Q++ + PF A G+ A++ +G G Sbjct: 193 GFMFVSLVILPVVAIIGLGGFDPLLQVMHTEGGGFTSPF--AFGFGAVIGLLGIG---FG 247 Query: 249 YLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVASGSIKVE-D 307 G PHI+ RYMS+++ +++R+ + IS +W ++ WGA G G A S+ D Sbjct: 248 SPGNPHILVRYMSLKNVKEMRQAAL-ISSVWNVLMGWGAVMIGLAGRAYFPDVSLLPNGD 306 Query: 308 PERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVL--GQELG 365 E++ + L GF++ +++A+MS+ADSQLLV SSA RDIY K+ ++L Sbjct: 307 QEQVFLMLGSEILHPLFFGFLLVAVLAAIMSSADSQLLVGSSAFVRDIYQKMFRRNRKLS 366 Query: 366 KKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTK 425 +K++V +SR+ +++ A T + ++ MV A+GGL FGP L LS +WK VT+ Sbjct: 367 QKKLVRLSRLTTVVFMGLSLILAFTAQEFVFWMVLFAFGGLGACFGPALLLSFYWKGVTR 426 Query: 426 EAGIVGMAYGLISEVILEAK-IYGWAFNPKAPGFFGT--LGQWFNGVPVFFINFFVTLFI 482 + + GM GL++ ++++ + + +AF P T G + VP F V I Sbjct: 427 QGVLWGMIAGLLTVILVKQQPQWTYAFLPDVKELLNTYFFGITYEAVP----GFIVATTI 482 Query: 483 IIIVSLLTKPPEDVVKLHEEL 503 +++SL TK P+ ++ E L Sbjct: 483 TVVISLFTKRPKHAKQIIERL 503 >pir||G64526 sodium/proline symporter - Helicobacter pylori (strain 26695) >gi|2313133|gb|AAD07125.1| (AE000527) proline permease (putP) [Helicobacter pylori 26695] Length = 496 Score = 299 bits (757), Expect = 6e-80 Identities = 166/501 (33%), Positives = 266/501 (52%), Gaps = 25/501 (4%) Query: 9 FLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFK 68 F++Y +++ YIG++ K +T + YF+G R + + + LS ASD SGWL++G PG+ + Sbjct: 14 FIVYSLLMLYIGFYFYKQNETTEDYFLGDRSMGPVISALSAGASDMSGWLLMGLPGALYV 73 Query: 69 AGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKF-RAITLPDYLEARLKDNTKLIRILSA 127 GL IG G L +++ + RLRIY +IT+ DY E R D+ ++R++SA Sbjct: 74 GGLINSHIAIGLSLGALINWVFVAKRLRIYTSVIANSITISDYFETRFSDDKHILRLISA 133 Query: 128 AIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQ 187 +IL+F Y+++ +G K F F + T + I +I+ +Y GG+ AV WTD++Q Sbjct: 134 FVILIFFIFYISSGLVSGAKLFEATFGIQYTYALSIGTLIIVSYTFLGGYKAVCWTDLIQ 193 Query: 188 AMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIV 247 + M+ LI++PI+ ++ +GG+ +II + P L G++ +V I +W + Sbjct: 194 GLLMMSALIVVPIVMIIHLGGIGEGIKIIREIKPENLSFLQGSS----VVAIISSLAWGL 249 Query: 248 GYLGQPHIVTRYMSVEDPRKLRRPGIFISGI-WTTIVLWGAFFAGFLGFALVASGSIKVE 306 GY GQPHI+ R+MS+ R + P GI W I L GA G LG A V + +E Sbjct: 250 GYFGQPHILVRFMSIRSIRDV--PKATTIGISWMVISLIGACVMGLLGVAYVHKFDLSLE 307 Query: 307 DPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGK 366 DPE+I M+ W+ G +++ I++AVMSTA SQLLV+SS IA D Y + ++ + Sbjct: 308 DPEKIFIVMSQLLFNPWITGILLSAILAAVMSTASSQLLVSSSTIAEDFYATIFNKDAPQ 367 Query: 367 KQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTKE 426 K ++ ISR+ V VA +A + + I +V+ AW G FG ++ SL+W R+T+ Sbjct: 368 KLVMAISRLSVLGVACIAFFISTDRNASILSIVSYAWAGFGASFGSVILFSLFWSRMTRI 427 Query: 427 AGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTLFIIIIV 486 I GM G S VIL + G+ F + F V I++ Sbjct: 428 GAIAGMLSG-ASTVIL----------------YDKFGKSFLDIYEIVPGFIVASVAIVVF 470 Query: 487 SLLTKPPEDVVKLHEELFKKV 507 SL + + E + K++ Sbjct: 471 SLFSSVRTGTKEAFETMLKEI 491 >pir||A71980 sodium/proline symporter - Helicobacter pylori (strain J99) >gi|4154554|gb|AAD05631.1| (AE001444) sodium/proline symporter [Helicobacter pylori J99] Length = 496 Score = 298 bits (754), Expect = 1e-79 Identities = 160/445 (35%), Positives = 251/445 (55%), Gaps = 10/445 (2%) Query: 9 FLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFK 68 F++Y +++ YIG++ K +T + YF+G R + + + LS ASD SGWL++G PG+ + Sbjct: 14 FVVYSLLMLYIGFYFYKQNETTEDYFLGDRSMGPVISALSAGASDMSGWLLMGLPGALYV 73 Query: 69 AGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKF-RAITLPDYLEARLKDNTKLIRILSA 127 GL IG G L +++ + RLRIY +IT+ DY E R D+ ++R++SA Sbjct: 74 GGLINSHIAIGLSLGALINWVFVAKRLRIYTSVIANSITISDYFETRFSDDKHILRLISA 133 Query: 128 AIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQ 187 +IL+F Y+++ +G K F F + T + I +I+ +Y GG+ AV WTD++Q Sbjct: 134 FVILIFFIFYISSGLVSGAKLFEATFGIQYTYALSIGTLIIVSYTFLGGYKAVCWTDLIQ 193 Query: 188 AMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIV 247 + M+ LI++PI+ ++ +GG+ +II + P L G++ +V I +W + Sbjct: 194 GLLMMSALIVVPIVMIIHLGGIGEGIKIIREIKPENLSFLQGSS----VVAIISSLAWGL 249 Query: 248 GYLGQPHIVTRYMSVEDPRKLRRPGIFISGI-WTTIVLWGAFFAGFLGFALVASGSIKVE 306 GY GQPHI+ R+MS+ R + P GI W I L GA G LG A V + +E Sbjct: 250 GYFGQPHILVRFMSIRSIRDV--PKATTIGISWMVISLIGACVMGLLGVAYVHKFDLSLE 307 Query: 307 DPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGK 366 DPE+I M+ W+ G +++ I++AVMSTA SQLLV+SS IA D Y + + + Sbjct: 308 DPEKIFIVMSQLLFNPWITGILLSAILAAVMSTASSQLLVSSSTIAEDFYATIFNKNAPQ 367 Query: 367 KQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTKE 426 K ++ ISR+ V VA +A + + I +V+ AW G FG ++ SL+W R+T+ Sbjct: 368 KLVMTISRLSVLGVACIAFFISTDKNASILSIVSYAWAGFGASFGSVILFSLFWSRMTRI 427 Query: 427 AGIVGMAYGLISEVILEAKIYGWAF 451 I GM G S VIL K +G +F Sbjct: 428 GAIAGMLSG-ASTVILYDK-FGKSF 450 >pir||T48676 proline uptake protein [validated] - Staphylococcus aureus >gi|2565311|gb|AAC38087.1| (AF024571) high affinity proline permease [Staphylococcus aureus] Length = 497 Score = 292 bits (740), Expect = 6e-78 Identities = 170/492 (34%), Positives = 259/492 (52%), Gaps = 31/492 (6%) Query: 11 IYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAG 70 +Y +IL + + + T +Y +GGR + LS ASD SGW+++G PGS + G Sbjct: 24 VYFLILMLLAFTYKQATGNLSEYMLGGRSIGPYITALSAGASDMSGWMIMGLPGSVYSTG 83 Query: 71 LGAFWAGIGCLFGTLADYLLIGPRLRIY---AGKFRAITLPDYLEARLKDNTKLIRILSA 127 L A W IG G +Y ++ PRLR+Y AG AITLPD+ + RL D +++I+S Sbjct: 84 LSAMWITIGLTLGAYINYFVVAPRLRVYTELAGD--AITLPDFFKNRLNDKNNVLKIISG 141 Query: 128 AIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQ 187 II+VF T Y + F +GGK F AF + G+++ I+ Y GG+ AV TD Q Sbjct: 142 LIIIVFFTLYTHSGFVSGGKLFESAFGLDYHFGLILVAFIVIFYTFFGGYLAVSITDFFQ 201 Query: 188 AMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIV 247 + ML+ ++++PI+A++ + G +A++ P L+ F G + + I SW + Sbjct: 202 GVIMLIAMVMVPIVAMMNLNGWG-TFHDVAAMKPTNLNLFKG----LSFIGIISLFSWGL 256 Query: 248 GYLGQPHIVTRYMSVEDPR---KLRRPGIFISGIWTTIVLWGAFFAGFLGFALVASGSIK 304 GY GQPHI+ R+MS++ + K RR GI W + L GA G G A V + IK Sbjct: 257 GYFGQPHIIVRFMSIKSHKMLPKARRLGI----SWMAVGLLGAVAVGLTGIAFVPAYHIK 312 Query: 305 VEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQEL 364 +EDPE + M+ V GF++A I++A+MST SQLLV SS++ D Y + G+E Sbjct: 313 LEDPETLFIVMSQVLFHPLVGGFLLAAILAAIMSTISSQLLVTSSSLTEDFYKLIRGEEK 372 Query: 365 GK---KQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWK 421 K K+ V I R+ V VA+VA+ A I +V AW G F P++ +L+WK Sbjct: 373 AKTHQKEFVMIGRLSVLVVAIVAIAIAWNPNDTILNLVGNAWAGFGASFSPLVLFALYWK 432 Query: 422 RVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTLF 481 +T+ + GM G + ++ A I A + G + + F V++ Sbjct: 433 GLTRAGAVSGMVSGALVVIVWIAWIKPLAHINEIFGLYEIIP-----------GFIVSVI 481 Query: 482 IIIIVSLLTKPP 493 + +VS LTK P Sbjct: 482 VTYVVSKLTKKP 493 >gb|AAA79365.1| (U06451) proline permease homolog [Staphylococcus aureus] Length = 497 Score = 292 bits (739), Expect = 8e-78 Identities = 170/492 (34%), Positives = 259/492 (52%), Gaps = 31/492 (6%) Query: 11 IYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAG 70 +Y +IL + + + T +Y +GGR + LS ASD SGW+++G PGS + G Sbjct: 24 VYFLILMLLAFTYKQATGNLSEYMLGGRSIGPYITALSAGASDMSGWMIMGLPGSVYSTG 83 Query: 71 LGAFWAGIGCLFGTLADYLLIGPRLRIY---AGKFRAITLPDYLEARLKDNTKLIRILSA 127 L A W IG G +Y ++ PRLR+Y AG AITLPD+ + RL D +++I+S Sbjct: 84 LSAMWITIGLTLGAYINYFVVAPRLRVYTELAGD--AITLPDFFKNRLNDKNNVLKIISG 141 Query: 128 AIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQ 187 II+VF T Y + F +GGK F AF + G+++ I+ Y GG+ AV TD Q Sbjct: 142 LIIVVFFTLYTHSGFVSGGKLFESAFGLDYHFGLILVAFIVIFYTFFGGYLAVSITDFFQ 201 Query: 188 AMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIV 247 + ML+ ++++PI+A++ + G +A++ P L+ F G + + I SW + Sbjct: 202 GVIMLIAMVMVPIVAMMNLNGWG-TFHDVAAMKPTNLNLFKG----LSFIGIISLFSWGL 256 Query: 248 GYLGQPHIVTRYMSVEDPR---KLRRPGIFISGIWTTIVLWGAFFAGFLGFALVASGSIK 304 GY GQPHI+ R+MS++ + K RR GI W + L GA G G A V + IK Sbjct: 257 GYFGQPHIIVRFMSIKSHKMLPKARRLGI----SWMAVGLLGAVAVGLTGIAFVPAYHIK 312 Query: 305 VEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQEL 364 +EDPE + M+ V GF++A I++A+MST SQLLV SS++ D Y + G+E Sbjct: 313 LEDPETLFIVMSQVLFHPLVGGFLLAAILAAIMSTISSQLLVTSSSLTEDFYKLIRGEEK 372 Query: 365 GK---KQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWK 421 K K+ V I R+ V VA+VA+ A I +V AW G F P++ +L+WK Sbjct: 373 AKTDQKEFVMIGRLSVLVVAIVAIAIAWNPNDTILNLVGNAWAGFGASFSPLVLFALYWK 432 Query: 422 RVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTLF 481 +T+ + GM G + ++ A I A + G + + F V++ Sbjct: 433 GLTRAGAVSGMVSGALVVIVWIAWIKPLAHINEIFGLYEIIP-----------GFIVSVI 481 Query: 482 IIIIVSLLTKPP 493 + +VS LTK P Sbjct: 482 VTYVVSKLTKKP 493 >pir||F83547 sodium/proline symporter PutP PA0783 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9946673|gb|AAG04172.1|AE004513_4 (AE004513) sodium/proline symporter PutP [Pseudomonas aeruginosa] Length = 506 Score = 291 bits (736), Expect = 2e-77 Identities = 170/502 (33%), Positives = 251/502 (49%), Gaps = 36/502 (7%) Query: 1 MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60 +N L F+IY+ + IG A + T Y +GGR + LS ASD SGWL++ Sbjct: 3 VNTPTLITFVIYIAAMVLIGLAAYRSTNNFSDYILGGRSLGSFVTALSAGASDMSGWLLM 62 Query: 61 GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNT 119 G PG+ + +GL W IG + G ++L + RLR+ A+TLPDY R +DN+ Sbjct: 63 GLPGAVYLSGLSESWIAIGLIVGAYLNWLFVAGRLRVQTEHNGNALTLPDYFTNRFEDNS 122 Query: 120 KLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFA 179 +L+RI SA +ILVF T Y A+ AG + F F +S T + AY GGF A Sbjct: 123 RLLRIFSALVILVFFTIYCASGIVAGARLFESTFGLSYETALWAGAAATIAYTFIGGFLA 182 Query: 180 VVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFA 239 V WTD VQA M+ LI+ P++ ++ GG++ I D GA+ + Sbjct: 183 VSWTDTVQASLMIFALILTPVIVMLATGGVEPTFTAIELKDATSFDMLKGAS----FIGV 238 Query: 240 IGYASWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFA 296 I +W +GY GQPHI+ R+M+ + + + RR IS W + L GA GF G A Sbjct: 239 ISLMAWGLGYFGQPHILARFMAADSVKSIPAARR----ISMTWMILCLGGAVAVGFFGIA 294 Query: 297 LVAS-----GSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAI 351 + G++ E+PER+ +A W+AG +++ I++AVMST QLLV SSA+ Sbjct: 295 YFQAHPEQAGAVS-ENPERVFIELAKILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSAL 353 Query: 352 ARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFG 411 D Y L + + ++V + R +V VA++A+W A + +V+ AW G FG Sbjct: 354 TEDFYKAFLRKGASQLELVWVGRAMVLLVAVIAIWLASNPENRVLGLVSYAWAGFGAAFG 413 Query: 412 PILTLSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPV 471 P++ SL WKR+T+ + GM G + VIL + GW G+ Sbjct: 414 PLVLFSLLWKRMTRNGALAGMIVG-AATVILWKNLLGW-----------------TGLYE 455 Query: 472 FFINFFVTLFIIIIVSLLTKPP 493 F I++ SLL K P Sbjct: 456 IIPGFLFASVAIVVFSLLGKAP 477 >gb|AAA99282.1| (L01140) proline permease [Salmonella sp.] >gi|154302|gb|AAA99283.1| (L01141) proline permease [Salmonella sp.] Length = 489 Score = 290 bits (734), Expect = 3e-77 Identities = 169/500 (33%), Positives = 261/500 (51%), Gaps = 41/500 (8%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F +Y+ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFCVYIFGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123 + F +G+ W IG G ++ L+ RLR++ A+TLPDY +R +D ++++R Sbjct: 67 AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTSRFEDKSRVLR 126 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 I+SA +IL+F T Y A+ AG + F F +S T + Y GGF AV WT Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243 D VQA M+ LI+ P++ +V +GG + ++I + G + AI+ +G Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243 Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297 W +GY GQPHI+ R+M+ + + RR IS W + L GA GF G A Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLTGAVAVGFFGIAFFNN 298 Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 +G++ ++ ER+ +A W+AG +++ I++AVMST QLLV SSAI D+ Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSAITEDL 357 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y L + G++++V + R++V VAL+A+ A + +V+ AW G FGP++ Sbjct: 358 YKAFLRKSAGQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLGQWFNGVPVFF 473 S+ W R+T+ + GM G ++ ++ K YGW PGF FG++G Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSIG---------- 465 Query: 474 INFFVTLFIIIIVSLLTKPP 493 I+I SLL K P Sbjct: 466 ---------IVIFSLLGKAP 476 >gb|AAA24465.1| (L01152) proline permease [Escherichia coli] Length = 489 Score = 289 bits (731), Expect = 7e-77 Identities = 162/470 (34%), Positives = 252/470 (53%), Gaps = 22/470 (4%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F +Y+ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123 + F +G+ W IG G ++ L+ RLR++ A+TLPDY R +D ++++R Sbjct: 67 AVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILR 126 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 I+SA +IL+F T Y A+ AG + F F +S T + V Y GGF AV WT Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGVAATILYTFIGGFLAVSWT 186 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243 D VQA M+ LI+ P++ ++ +GG + ++I + G + AI+ +G Sbjct: 187 DTVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243 Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297 W +GY GQPHI+ R+M+ + + RR IS W + L GA GF G A Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNE 298 Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 +G++ ++ ER+ +A W+AG +++ I++AVMST QLLV SSAI D+ Sbjct: 299 HPAVAGAVN-QNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y L + +K++V + R++V VALVA+ A + +V+ AW G FGP++ Sbjct: 358 YKAFLRKHASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVL 417 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGW-AFNPKAPGF-FGTLG 463 S+ W R+T+ + GM G ++ ++ K +GW PGF FG++G Sbjct: 418 FSVMWSRMTRNGALAGMIIGALTVIVW--KQFGWLGLYEIIPGFIFGSIG 465 >gb|AAA24461.1| (L01132) proline permease [Escherichia coli] >gi|147447|gb|AAA24467.1| (L01154) proline permease [Escherichia coli] >gi|147451|gb|AAA24469.1| (L01156) proline permease [Escherichia coli] Length = 489 Score = 288 bits (729), Expect = 1e-76 Identities = 161/470 (34%), Positives = 252/470 (53%), Gaps = 22/470 (4%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F +Y+ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123 + F +G+ W IG G ++ L+ RLR++ A+TLPDY R +D ++++R Sbjct: 67 AVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILR 126 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 I+SA +IL+F T Y A+ AG + F F +S T + Y GGF AV WT Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGFLAVSWT 186 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243 D VQA M+ LI+ P++ ++ +GG + ++I + G + AI+ +G Sbjct: 187 DTVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243 Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297 W +GY GQPHI+ R+M+ + + RR IS W + L GA GF G A Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNE 298 Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 +G++ ++ ER+ +A W+AG +++ I++AVMST QLLV SSAI D+ Sbjct: 299 HPAVAGAVN-QNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y L ++ +K++V + R++V VALVA+ A + +V+ AW G FGP++ Sbjct: 358 YKAFLRKQASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVL 417 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGW-AFNPKAPGF-FGTLG 463 S+ W R+T+ + GM G ++ ++ K +GW PGF FG++G Sbjct: 418 FSVMWSRMTRNGALAGMIIGALTVIVW--KQFGWLGLYEIIPGFIFGSIG 465 >gb|AAA99281.1| (L01139) proline permease [Salmonella sp.] Length = 489 Score = 287 bits (728), Expect = 2e-76 Identities = 167/505 (33%), Positives = 262/505 (51%), Gaps = 41/505 (8%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F +Y++ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFCVYILGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123 + F +G+ W IG G ++ L+ RLR++ A+TLPDY R +D ++++R Sbjct: 67 AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 I+SA +IL+F T Y A+ AG + F F +S T + Y GGF AV WT Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243 D VQA M+ LI+ P++ +V +GG + ++I + G + AI+ +G Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKG-LNFVAIISLMG-- 243 Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297 W +GY GQPHI+ R+M+ + + RR IS W + L GA GF G A Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298 Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 +G++ ++ ER+ +A W+AG +++ I++AVMST QLLV SSAI D+ Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y L + ++++V + R++V VAL+A+ A + +V+ AW G FGP++ Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLGQWFNGVPVFF 473 S+ W R+T+ + GM G ++ ++ K YGW PGF FG++G Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSMG---------- 465 Query: 474 INFFVTLFIIIIVSLLTKPPEDVVK 498 I++ SLL K P ++ Sbjct: 466 ---------IVVFSLLGKAPTAAIQ 481 >gb|AAA99284.1| (L01142) proline permease [Salmonella sp.] >gi|154306|gb|AAA99285.1| (L01143) proline permease [Salmonella sp.] Length = 489 Score = 287 bits (728), Expect = 2e-76 Identities = 163/470 (34%), Positives = 252/470 (52%), Gaps = 22/470 (4%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F +Y++ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFCVYILGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123 + F +G+ W IG G ++ L+ RLR++ A+TLPDY R +D ++++R Sbjct: 67 AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 I+SA +IL+F T Y A+ AG + F F +S T + Y GGF AV WT Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243 D VQA M+ LI+ P++ +V +GG + ++I + G + AI+ +G Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243 Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297 W +GY GQPHI+ R+M+ + + RR IS W + L GA GF G A Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298 Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 +G++ ++ ER+ +A WVAG +++ I++AVMST QLLV SSAI D+ Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWVAGVLLSAILAAVMSTLSCQLLVCSSAITEDL 357 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y L + ++++V + R++V VALVA+ A + +V+ AW G FGP++ Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALVAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLG 463 S+ W R+T+ + GM G ++ ++ K YGW PGF FG++G Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSMG 465 >gb|AAA99286.1| (L01144) proline permease [Salmonella sp.] >gi|154310|gb|AAA99287.1| (L01145) proline permease [Salmonella sp.] Length = 489 Score = 287 bits (728), Expect = 2e-76 Identities = 162/470 (34%), Positives = 252/470 (53%), Gaps = 22/470 (4%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F +Y++ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFCVYILGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123 + F +G+ W IG G ++ L+ RLR++ A+TLPDY R +D ++++R Sbjct: 67 AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 I+SA +IL+F T Y A+ AG + F F +S T + Y GGF AV WT Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243 D VQA M+ LI+ P++ +V +GG + ++I + G + AI+ +G Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243 Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297 W +GY GQPHI+ R+M+ + + RR IS W + L GA GF G A Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298 Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 +G++ ++ ER+ +A W+AG +++ I++AVMST QLLV SSAI D+ Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y L + ++++V + R++V VALVA+ A + +V+ AW G FGP++ Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALVAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLG 463 S+ W R+T+ + GM G ++ ++ K YGW PGF FG++G Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSMG 465 >sp|P10502|PUTP_SALTY SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE) >gi|47849|emb|CAA36802.1| (X52573) proline permease (AA 1-502) [Salmonella typhimurium] Length = 502 Score = 287 bits (727), Expect = 2e-76 Identities = 169/500 (33%), Positives = 259/500 (51%), Gaps = 41/500 (8%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F +Y+ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123 + F +G+ W IG G ++ L+ RLR++ A+TLPDY R +D ++++R Sbjct: 67 AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 I+SA +IL+F T Y A+ AG + F F +S T + Y GGF AV WT Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243 D VQA M+ LI+ P++ +V +GG + ++I + G + AI+ +G Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKG-LNFVAIISLMG-- 243 Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297 W +GY GQPHI+ R+M+ + + RR IS W + L GA GF G A Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298 Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 +G++ ++ ER+ +A W+AG +++ I++AVMST QLLV SSAI D+ Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSAITEDL 357 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y L + ++++V + R++V VAL+A+ A + +V+ AW G FGP++ Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLGQWFNGVPVFF 473 S+ W R+T+ + GM G ++ ++ K YGW PGF FG+LG Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSLG---------- 465 Query: 474 INFFVTLFIIIIVSLLTKPP 493 I+I SLL K P Sbjct: 466 ---------IVIFSLLGKAP 476 >gb|AAA27199.1| (L01135) proline permease [Salmonella typhimurium] Length = 489 Score = 287 bits (727), Expect = 2e-76 Identities = 169/500 (33%), Positives = 259/500 (51%), Gaps = 41/500 (8%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F +Y+ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123 + F +G+ W IG G ++ L+ RLR++ A+TLPDY R +D ++++R Sbjct: 67 AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 I+SA +IL+F T Y A+ AG + F F +S T + Y GGF AV WT Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243 D VQA M+ LI+ P++ +V +GG + ++I + G + AI+ +G Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKG-LNFVAIISLMG-- 243 Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297 W +GY GQPHI+ R+M+ + + RR IS W + L GA GF G A Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298 Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 +G++ ++ ER+ +A W+AG +++ I++AVMST QLLV SSAI D+ Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSAITEDL 357 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y L + ++++V + R++V VAL+A+ A + +V+ AW G FGP++ Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLGQWFNGVPVFF 473 S+ W R+T+ + GM G ++ ++ K YGW PGF FG+LG Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSLG---------- 465 Query: 474 INFFVTLFIIIIVSLLTKPP 493 I+I SLL K P Sbjct: 466 ---------IVIFSLLGKAP 476 >gb|AAA26389.1| (L01134) proline permease [Rickettsia typhi] Length = 489 Score = 287 bits (727), Expect = 2e-76 Identities = 169/500 (33%), Positives = 259/500 (51%), Gaps = 41/500 (8%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F +Y+ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123 + F +G+ W IG G ++ L+ RLR++ A+TLPDY R +D ++++R Sbjct: 67 AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 I+SA +IL+F T Y A+ AG + F F +S T + Y GGF AV WT Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243 D VQA M+ LI+ P++ +V +GG + ++I + G + AI+ +G Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKG-LNFVAIISLMG-- 243 Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297 W +GY GQPHI+ R+M+ + + RR IS W + L GA GF G A Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298 Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 +G++ ++ ER+ +A W+AG +++ I++AVMST QLLV SSAI D+ Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSAITEDL 357 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y L + ++++V + R++V VAL+A+ A + +V+ AW G FGP++ Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLGQWFNGVPVFF 473 S+ W R+T+ + GM G ++ ++ K YGW PGF FG+LG Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSLG---------- 465 Query: 474 INFFVTLFIIIIVSLLTKPP 493 I+I SLL K P Sbjct: 466 ---------IVIFSLLGKAP 476 >gb|AAA24466.1| (L01153) proline permease [Escherichia coli] >gi|147453|gb|AAA24470.1| (L01157) proline permease [Escherichia coli] >gi|147455|gb|AAA24471.1| (L01158) proline permease [Escherichia coli] >gi|147457|gb|AAA24472.1| (L01159) proline permease [Escherichia coli] Length = 489 Score = 287 bits (727), Expect = 2e-76 Identities = 161/470 (34%), Positives = 251/470 (53%), Gaps = 22/470 (4%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F +Y+ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123 + F +G+ W IG G ++ L+ RLR++ A+TLPDY R +D ++++R Sbjct: 67 AVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILR 126 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 I+SA +IL+F T Y A+ AG + F F +S T + Y GGF AV WT Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGFLAVSWT 186 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243 D VQA M+ LI+ P++ ++ +GG + ++I + G + AI+ +G Sbjct: 187 DTVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243 Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297 W +GY GQPHI+ R+M+ + + RR IS W + L GA GF G A Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNE 298 Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 +G++ ++ ER+ +A W+AG +++ I++AVMST QLLV SSAI D+ Sbjct: 299 HPAVAGAVN-QNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y L + +K++V + R++V VALVA+ A + +V+ AW G FGP++ Sbjct: 358 YKAFLRKHASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVL 417 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGW-AFNPKAPGF-FGTLG 463 S+ W R+T+ + GM G ++ ++ K +GW PGF FG++G Sbjct: 418 FSVMWSRMTRNGALAGMIIGALTVIVW--KQFGWLGLYEIIPGFIFGSIG 465 >sp|P07117|PUTP_ECOLI SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE) >gi|72512|pir||JGECPP sodium/proline symporter - Escherichia coli >gi|42602|emb|CAA29143.1| (X05653) putP proline carrier (AA 1-502) [Escherichia coli] >gi|1651504|dbj|BAA35793.1| (D90738) Proline carrier protein [Escherichia coli] >gi|1787251|gb|AAC74100.1| (AE000203) major sodium/proline symporter [Escherichia coli K12] >gi|225963|prf||1404369A Pro carrier protein [Escherichia coli] Length = 502 Score = 287 bits (726), Expect = 3e-76 Identities = 161/470 (34%), Positives = 251/470 (53%), Gaps = 22/470 (4%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F +Y+ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123 + F +G+ W IG G ++ L+ RLR++ A+TLPDY R +D ++++R Sbjct: 67 AVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILR 126 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 I+SA +IL+F T Y A+ AG + F F +S T + Y GGF AV WT Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGFLAVSWT 186 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243 D VQA M+ LI+ P++ ++ +GG + ++I + G + AI+ +G Sbjct: 187 DTVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243 Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297 W +GY GQPHI+ R+M+ + + RR IS W + L GA GF G A Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFND 298 Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 +G++ ++ ER+ +A W+AG +++ I++AVMST QLLV SSAI D+ Sbjct: 299 HPALAGAVN-QNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y L + +K++V + R++V VALVA+ A + +V+ AW G FGP++ Sbjct: 358 YKAFLRKHASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVL 417 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGW-AFNPKAPGF-FGTLG 463 S+ W R+T+ + GM G ++ ++ K +GW PGF FG++G Sbjct: 418 FSVMWSRMTRNGALAGMIIGALTVIVW--KQFGWLGLYEIIPGFIFGSIG 465 >gb|AAA24463.1| (L01150) proline permease [Escherichia coli] >gi|147441|gb|AAA24464.1| (L01151) proline permease [Escherichia coli] Length = 489 Score = 287 bits (726), Expect = 3e-76 Identities = 161/470 (34%), Positives = 251/470 (53%), Gaps = 22/470 (4%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F +Y+ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123 + F +G+ W IG G ++ L+ RLR++ A+TLPDY R +D ++++R Sbjct: 67 AVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILR 126 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 I+SA +IL+F T Y A+ AG + F F +S T + Y GGF AV WT Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGFLAVSWT 186 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243 D VQA M+ LI+ P++ ++ +GG + ++I + G + AI+ +G Sbjct: 187 DTVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243 Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297 W +GY GQPHI+ R+M+ + + RR IS W + L GA GF G A Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFND 298 Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 +G++ ++ ER+ +A W+AG +++ I++AVMST QLLV SSAI D+ Sbjct: 299 HPALAGAVN-QNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y L + +K++V + R++V VALVA+ A + +V+ AW G FGP++ Sbjct: 358 YKAFLRKHASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVL 417 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGW-AFNPKAPGF-FGTLG 463 S+ W R+T+ + GM G ++ ++ K +GW PGF FG++G Sbjct: 418 FSVMWSRMTRNGALAGMIIGALTVIVW--KQFGWLGLYEIIPGFIFGSIG 465 >gb|AAA99278.1| (L01136) proline permease [Salmonella sp.] Length = 489 Score = 287 bits (726), Expect = 3e-76 Identities = 169/500 (33%), Positives = 259/500 (51%), Gaps = 41/500 (8%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F +Y+ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFCVYIFGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123 + F +G+ W IG G ++ L+ RLR++ A+TLPDY R +D ++++R Sbjct: 67 AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 I+SA +IL+F T Y A+ AG + F F +S T + Y GGF AV WT Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243 D VQA M+ LI+ P++ +V +GG + ++I + G + AI+ +G Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKG-LNFVAIISLMG-- 243 Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297 W +GY GQPHI+ R+M+ + + RR IS W + L GA GF G A Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298 Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 +G++ ++ ER+ +A WVAG +++ I++AVMST QLLV SSAI D+ Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWVAGVLLSAILAAVMSTLSCQLLVCSSAITEDL 357 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y L + ++++V + R++V VAL+A+ A + +V+ AW G FGP++ Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLGQWFNGVPVFF 473 S+ W R+T+ + GM G ++ ++ K YGW PGF FG++G Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSIG---------- 465 Query: 474 INFFVTLFIIIIVSLLTKPP 493 I+I SLL K P Sbjct: 466 ---------IVIFSLLGKAP 476 >gb|AAA24462.1| (L01133) proline permease [Escherichia coli] Length = 489 Score = 287 bits (726), Expect = 3e-76 Identities = 161/470 (34%), Positives = 251/470 (53%), Gaps = 22/470 (4%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F +Y+ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123 + F +G+ W IG G ++ L+ RLR++ A+TLPDY R +D ++++R Sbjct: 67 AVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILR 126 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 I+SA +IL+F T Y A+ AG + F F +S T + Y GGF AV WT Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGFLAVSWT 186 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243 D VQA M+ LI+ P++ ++ +GG + ++I + G + AI+ +G Sbjct: 187 DTVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243 Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFALV-- 298 W +GY GQPHI+ R+M+ + + RR IS W + L GA GF G A Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNE 298 Query: 299 ---ASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 +G++ ++ ER+ +A W+AG +++ I++AVMST QLLV SSAI D+ Sbjct: 299 HPSVAGAVN-QNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y L + +K++V + R++V VALVA+ A + +V+ AW G FGP++ Sbjct: 358 YKAFLRKHASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVL 417 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGW-AFNPKAPGF-FGTLG 463 S+ W R+T+ + GM G ++ ++ K +GW PGF FG++G Sbjct: 418 FSVMWSRMTRNGALAGMIIGALTVIVW--KQFGWLGLYEIIPGFIFGSIG 465 >gb|AAA99279.1| (L01137) proline permease [Salmonella sp.] Length = 489 Score = 287 bits (726), Expect = 3e-76 Identities = 169/500 (33%), Positives = 259/500 (51%), Gaps = 41/500 (8%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F +Y+ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFCVYIFGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123 + F +G+ W IG G ++ L+ RLR++ A+TLPDY R +D ++++R Sbjct: 67 AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 I+SA +IL+F T Y A+ AG + F F +S T + Y GGF AV WT Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243 D VQA M+ LI+ P++ +V +GG + ++I + G + AI+ +G Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKG-LNFVAIISLMG-- 243 Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297 W +GY GQPHI+ R+M+ + + RR IS W + L GA GF G A Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298 Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 +G++ ++ ER+ +A WVAG +++ I++AVMST QLLV SSAI D+ Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWVAGVLLSAILAAVMSTLSCQLLVCSSAITEDL 357 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y L + ++++V + R++V VAL+A+ A + +V+ AW G FGP++ Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLGQWFNGVPVFF 473 S+ W R+T+ + GM G ++ ++ K YGW PGF FG++G Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSIG---------- 465 Query: 474 INFFVTLFIIIIVSLLTKPP 493 I+I SLL K P Sbjct: 466 ---------IVIFSLLGKAP 476 >gb|AAA99280.1| (L01138) proline permease [Salmonella sp.] Length = 489 Score = 287 bits (726), Expect = 3e-76 Identities = 167/505 (33%), Positives = 262/505 (51%), Gaps = 41/505 (8%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F +Y++ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFCVYILGMLLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123 + F +G+ W IG G ++ L+ RLR++ A+TLPDY R +D ++++R Sbjct: 67 AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 I+SA +IL+F T Y A+ AG + F F +S T + Y GGF AV WT Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243 D VQA M+ LI+ P++ +V +GG + ++I + G + AI+ +G Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKG-LNFVAIISLMG-- 243 Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297 W +GY GQPHI+ R+M+ + + RR IS W + L GA GF G A Sbjct: 244 -WGLGYFGQPHILARFMAADSHYSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298 Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 +G++ ++ ER+ +A W+AG +++ I++AVMST QLLV SSAI D+ Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y L + ++++V + R++V VAL+A+ A + +V+ AW G FGP++ Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLGQWFNGVPVFF 473 S+ W R+T+ + GM G ++ ++ K YGW PGF FG++G Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSMG---------- 465 Query: 474 INFFVTLFIIIIVSLLTKPPEDVVK 498 I++ SLL K P ++ Sbjct: 466 ---------IVVFSLLGKAPTAAIQ 481 >gb|AAA24468.1| (L01155) proline permease [Escherichia coli] Length = 489 Score = 286 bits (725), Expect = 3e-76 Identities = 160/470 (34%), Positives = 251/470 (53%), Gaps = 22/470 (4%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F +Y+ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123 + F +G+ W IG G ++ L+ RLR++ A+TLPDY R +D ++++R Sbjct: 67 AVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILR 126 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 I+SA +IL+F T Y A+ AG + F F +S T + Y GGF AV WT Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGFLAVSWT 186 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243 D VQA M+ LI+ P++ ++ +GG + ++I + G + AI+ +G Sbjct: 187 DTVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243 Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297 W +GY GQPHI+ R+M+ + + RR IS W + L GA GF G A Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNE 298 Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 +G++ ++ ER+ +A W+AG +++ I++AVMST QLLV SSAI D+ Sbjct: 299 HPAVAGAVN-QNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y + + +K++V + R++V VALVA+ A + +V+ AW G FGP++ Sbjct: 358 YKAFMRKHASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVL 417 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGW-AFNPKAPGF-FGTLG 463 S+ W R+T+ + GM G ++ ++ K +GW PGF FG++G Sbjct: 418 FSVMWSRMTRNGALAGMIIGALTVIVW--KQFGWLGLYEIIPGFIFGSIG 465 >pir||JC2382 sodium/proline symporter - Pseudomonas fluorescens >gi|509694|dbj|BAA06838.1| (D32069) proline permease [Pseudomonas fluorescens] >gi|913690|gb|AAC60490.1| (S76070) proline permease [Pseudomonas fluorescens, Peptide, 494 aa] >gi|1092517|prf||2024229A Pro permease [Pseudomonas fluorescens] Length = 494 Score = 286 bits (724), Expect = 5e-76 Identities = 158/444 (35%), Positives = 233/444 (51%), Gaps = 16/444 (3%) Query: 6 LFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65 L F+IY+ + IG A + T Y +GGR + + LS ASD SGWL++G PG+ Sbjct: 8 LITFVIYIAAMVLIGLMAYRSTNNLSDYILGGRSLGSVVTALSAGASDMSGWLLMGLPGA 67 Query: 66 AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIRI 124 + +GL W IG + G ++L + RLR+ A+TLPDY +R +D + L+RI Sbjct: 68 IYMSGLSESWIAIGLIVGAYLNWLFVAGRLRVQTEHNGDALTLPDYFSSRFEDKSGLLRI 127 Query: 125 LSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTD 184 +SA +ILVF T Y A+ AG + F F +S T + AY GGF AV WTD Sbjct: 128 ISAVVILVFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIAYTFIGGFLAVSWTD 187 Query: 185 VVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYAS 244 VQA M+ LI+ PI+ L+ GG+D I + DP T + I Sbjct: 188 TVQATLMIFALILTPIIVLLATGGVDTTFLAIEAKDPTSFDMLKNTT----FIGIISLMG 243 Query: 245 WIVGYLGQPHIVTRYM---SVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVAS- 300 W +GY GQPHI+ R+M SV+ K RR IS W + L G GF G A ++ Sbjct: 244 WGLGYFGQPHILARFMAADSVKSIAKARR----ISMTWMILCLGGTVAVGFFGIAYFSAH 299 Query: 301 ---GSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYH 357 E+PER+ +A WVAG +++ I++AVMST QLLV SSA+ D Y Sbjct: 300 PEVAGPVTENPERVFIELAKILFNPWVAGVLLSAILAAVMSTLSCQLLVCSSALTEDFYK 359 Query: 358 KVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLS 417 L + ++++V + R++V VAL+A+ A + +V+ AW G FGP++ +S Sbjct: 360 AFLRKGASQRELVWVGRLMVLVVALIAIAMAANPENRVLGLVSYAWAGFGAAFGPVVLIS 419 Query: 418 LWWKRVTKEAGIVGMAYGLISEVI 441 + WK +T+ + G+ G I+ ++ Sbjct: 420 VIWKHMTRNGALAGILVGAITVIV 443 >gb|AAA99288.1| (L01146) proline permease [Salmonella sp.] >gi|154314|gb|AAA99289.1| (L01147) proline permease [Salmonella sp.] Length = 489 Score = 286 bits (724), Expect = 5e-76 Identities = 161/470 (34%), Positives = 251/470 (53%), Gaps = 22/470 (4%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F +Y+ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123 + F +G+ W IG G ++ L+ RLR++ A+TLPDY R +D ++++R Sbjct: 67 AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 I+SA +IL+F T Y A+ AG + F F +S T + Y GGF AV WT Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243 D VQA M+ LI+ P++ +V +GG + ++I + G + AI+ +G Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKG-LNFVAIISLMG-- 243 Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297 W +GY GQPHI+ R+M+ + + RR IS W + L GA GF G A Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298 Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 +G++ ++ ER+ +A W+AG +++ I++AVMST QLLV SSAI D+ Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDL 357 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y L + ++++V + R++V VAL+A+ A + +V+ AW G FGP++ Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPNNRVLGLVSYAWAGFGAAFGPVVL 417 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGW-AFNPKAPGF-FGTLG 463 S+ W R+T+ + GM G ++ ++ K YGW PGF FG++G Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLELYEIIPGFIFGSIG 465 >gb|AAA99291.1| (L01149) proline permease [Salmonella sp.] Length = 489 Score = 286 bits (723), Expect = 6e-76 Identities = 161/470 (34%), Positives = 250/470 (52%), Gaps = 22/470 (4%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F +Y+ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123 + F +G+ W IG G ++ L+ RLR++ A+TLPDY R +D ++++R Sbjct: 67 AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 I+SA +IL+F T Y A+ AG + F F +S T + Y GGF AV WT Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243 D VQA M+ LI+ P++ +V +GG + ++I + G + AI+ +G Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKG-LNFVAIISLMG-- 243 Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297 W +GY GQPHI+ R+M+ + + RR IS W + L GA GF G A Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298 Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 +G++ ++ ER+ +A W+AG +++ I++AVMST QLLV SSAI D+ Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSAITEDL 357 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y L + ++++V + R++V VAL+A+ A + +V AW G FGP++ Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVTYAWAGFGAAFGPVVL 417 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLG 463 S+ W R+T+ + GM G ++ ++ K YGW PGF FG++G Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSIG 465 >pir||S10220 sodium/proline symporter - Salmonella typhimurium Length = 502 Score = 284 bits (720), Expect = 1e-75 Identities = 160/470 (34%), Positives = 250/470 (53%), Gaps = 22/470 (4%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F +Y+ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123 + F +G+ W IG G ++ L+ RLR++ A+TLPDY R +D ++++R Sbjct: 67 AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 I+SA +IL+F T Y + AG + F F +S T + Y GGF AV WT Sbjct: 127 IISALVILLFFTIYCGSGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243 D VQA M+ LI+ P++ +V +GG + ++I + G + AI+ +G Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKGLN-FVAIISLMG-- 243 Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297 W +GY GQPHI+ R+M+ + + RR IS W + L GA GF G A Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298 Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 +G++ ++ ER+ +A W+AG +++ I++AVMST Q+LV SSAI D+ Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQMLVCSSAITEDL 357 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y L + ++++V + R++V VAL+A+ A + +V+ AW G FGP++ Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVSYAWAGFGAAFGPVVL 417 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLG 463 S+ W R+T+ + GM G ++ ++ K YGW PGF FG+LG Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSLG 465 >gb|AAA99290.1| (L01148) proline permease [Salmonella sp.] Length = 489 Score = 284 bits (719), Expect = 2e-75 Identities = 166/500 (33%), Positives = 258/500 (51%), Gaps = 41/500 (8%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F +Y+ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIR 123 + F +G+ W IG G ++ L+ RLR++ A+TLPDY R +D ++++R Sbjct: 67 AIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEFNNNALTLPDYFTGRFEDKSRVLR 126 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 I+SA +IL+F T Y A+ AG + F F +S T + Y GGF AV WT Sbjct: 127 IISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIIYTFIGGFLAVSWT 186 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYA 243 D VQA M+ LI+ P++ +V +GG + ++I + G + AI+ +G Sbjct: 187 DTVQASLMIFALILTPVMVIVGVGGFSESLEVIKQKSIENVDMLKG-LNFVAIISLMG-- 243 Query: 244 SWIVGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFAL--- 297 W +GY GQPHI+ R+M+ + + RR IS W + L GA GF G A Sbjct: 244 -WGLGYFGQPHILARFMAADSHHSIVHARR----ISMTWMILCLAGAVAVGFFGIAYFNN 298 Query: 298 --VASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 +G++ ++ ER+ +A W+AG +++ I++AVMST QLLV SSAI D+ Sbjct: 299 NPALAGAVN-QNSERVFIELAQILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSAITEDL 357 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y L + ++++V + R++V VAL+A+ A + +V AW G FGP++ Sbjct: 358 YKAFLRKSASQQELVWVGRVMVLVVALIAIALAANPDNRVLGLVTYAWAGFGAAFGPVVL 417 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWA-FNPKAPGF-FGTLGQWFNGVPVFF 473 S+ W R+T+ + GM G ++ ++ K YGW PGF FG++ Sbjct: 418 FSVMWSRMTRNGALAGMIIGAVTVIVW--KQYGWLDLYEIIPGFIFGSI----------- 464 Query: 474 INFFVTLFIIIIVSLLTKPP 493 +I++ SLL K P Sbjct: 465 --------VIVLFSLLGKAP 476 >pir||G81202 sodium/proline symporter NMB0402 [imported] - Neisseria meningitidis (group B strain MD58, group A strain Z2491) >gi|7225624|gb|AAF40841.1| (AE002396) sodium/proline symporter [Neisseria meningitidis MC58] >gi|7380708|emb|CAB85299.1| (AL162758) sodium/proline symporter [Neisseria meningitidis Z2491] Length = 508 Score = 280 bits (708), Expect = 3e-74 Identities = 170/495 (34%), Positives = 254/495 (50%), Gaps = 23/495 (4%) Query: 9 FLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFK 68 F IYLV + IG A T+ D Y +GGR + +S ASD SGWL++G PG+ + Sbjct: 8 FAIYLVAVLLIGLAAYFSTRNFDDYILGGRSLGPFVTAMSAGASDMSGWLLMGLPGAIYL 67 Query: 69 AGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFR-AITLPDYLEARLKDNTKLIRILSA 127 +GL W IG L G ++LL+ RLR++ A+TLPDY R L++++SA Sbjct: 68 SGLNEAWIAIGLLVGAYFNWLLVAGRLRVHTEYANNALTLPDYFFHRFGAGGHLMKVVSA 127 Query: 128 AIILVFMTAYVAAQFAAGGKTFAQAFN-VSVTTGILITVIILTAYVITGGFFAVVWTDVV 186 IIL F T Y A+ AG F F ++ + + AY GGF AV WTD + Sbjct: 128 LIILFFFTIYCASGIVAGATLFQSLFEGMTYNQAMWLGAGATIAYTFLGGFLAVSWTDTL 187 Query: 187 QAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWI 246 QA M+ LI+ P++ + +GG ++ + I SV +G ++ I A+W Sbjct: 188 QASLMIFALILTPVMVYLGLGGAEQMSAAIQSVAAGTGKEYGSLFAGTTVIGIISTAAWG 247 Query: 247 VGYLGQPHIVTRYMSVEDPRKL---RRPGIFISGIWTTIVLWGAFFAGFLGFALVASGSI 303 +GY GQPHI+ R+M+ E + L RR G+ W + L GA G+ G A + Sbjct: 248 LGYFGQPHILARFMAAESAKSLVSARRIGM----TWMALCLAGAVAVGYFGIAYFGANPD 303 Query: 304 KVE----DPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKV 359 KV + ERI A++ W+AG +++ I++AVMST QLLV SSAI D Y Sbjct: 304 KVSSMSGNHERIFIALSTLLFNPWIAGIILSAILAAVMSTLSCQLLVCSSAITEDFYKGF 363 Query: 360 LGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLW 419 L + + ++V + R++V A+A++++ A + +V+ AW G FGPI+ LS+ Sbjct: 364 LRKNAQQSELVWVGRLMVLAIAVISILIASDPNSKVLGLVSYAWAGFGAAFGPIVILSVL 423 Query: 420 WKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNP-KAPGFFGTLGQWFNGVPVFFINFFV 478 WKR+T + GM G ++ V+ W P +A G G L + VP F V Sbjct: 424 WKRITAYGALSGMVAGALTVVVWAE----WVKKPAQAAGESGLL-TMYEIVP----GFIV 474 Query: 479 TLFIIIIVSLLTKPP 493 L + ++VSL K P Sbjct: 475 CLIVAVLVSLFNKEP 489 >gb|AAF25001.1|AF153207_2 (AF153207) proline permease [Pseudomonas putida] >gi|8132050|gb|AAF73192.1|AF151964_1 (AF151964) proline permease [Pseudomonas putida] Length = 492 Score = 278 bits (703), Expect = 1e-73 Identities = 169/502 (33%), Positives = 253/502 (49%), Gaps = 37/502 (7%) Query: 9 FLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFK 68 F+IY+ + IG+ A + T Y +GGR + + LS ASD SGWL++G PG+ + Sbjct: 9 FVIYIAAMVLIGFAAYRATNNLSDYILGGRSLGSVVTALSAGASDMSGWLLMGLPGAIYF 68 Query: 69 AGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIRILSA 127 AGL W IG G ++L + RLR+ A+TLPDY +R +DN+ L+RI+SA Sbjct: 69 AGLSEAWIAIGLTVGAYLNWLFVAGRLRVQTEHNGDALTLPDYFSSRFEDNSGLLRIISA 128 Query: 128 AIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQ 187 +ILVF T Y A+ AG + F F +S T + AY GGF AV WTD VQ Sbjct: 129 IVILVFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATIAYTFVGGFLAVSWTDTVQ 188 Query: 188 AMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIV 247 A M+ LI+ P++ L+ GG D+ I +V+ GAT + I W + Sbjct: 189 ASLMIFALILTPVIVLISTGGFDQTFAAIEAVNRRNFDMLKGAT----FIGIISLMGWGL 244 Query: 248 GYLGQPHIVTRYM---SVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVA----- 299 GY PHI+ R+M SV K RR IS W + L G GF G A + Sbjct: 245 GYFRPPHILARFMAADSVNSIAKARR----ISMTWMILCLAGTCAVGFCGIAYFSAHPEL 300 Query: 300 SGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKV 359 +G + E+ +R+ +A WVAG +++ I++AVM T QLLV SSA+ + Y Sbjct: 301 AGPVS-ENHKRVFIELAKILFNPWVAGVLLSAILAAVMITLSCQLLVCSSALTENFYKAF 359 Query: 360 LGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLW 419 L + + ++V + R++V AVAL+A+ A + +VA AW G FGP++ +S+ Sbjct: 360 LRKNASQVELVWVGRLMVLAVALIAIAMAANPENRVLGLVAYAWAGFGAAFGPVVLISVL 419 Query: 420 WKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVT 479 WK +T+ + G+ G ++ ++ + F TLG + +P F Sbjct: 420 WKGMTRNGALAGIVVGALTVILWKN--------------FDTLG-LYEIIP----GFLFA 460 Query: 480 LFIIIIVSLLTKPPEDVVKLHE 501 I++VS L P + +VK E Sbjct: 461 SIAIVLVSKLGSPSQTMVKRFE 482 >pir||B69759 sodium/proline symporter ycgO - Bacillus subtilis >gi|1805394|dbj|BAA08956.1| (D50453) homologue of proline permease of E. coli [Bacillus subtilis] >gi|2632608|emb|CAB12116.1| (Z99105) similar to proline permease [Bacillus subtilis] Length = 449 Score = 277 bits (702), Expect = 2e-73 Identities = 159/452 (35%), Positives = 237/452 (52%), Gaps = 24/452 (5%) Query: 47 LSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKF-RAI 105 LS A+D SGWL++G PG+ F GL W IG G A++L + PRLR Y K +I Sbjct: 8 LSAGAADMSGWLLMGLPGAMFSTGLSGAWIVIGLCLGAWANWLYVAPRLRTYTEKAGNSI 67 Query: 106 TLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITV 165 T+P +LE R D TKL+R+ S +ILVF T YV++ +GG F + TG+ I Sbjct: 68 TIPGFLENRFGDQTKLLRLFSGIVILVFFTFYVSSGMVSGGVLFNSILGMDYHTGLWIVT 127 Query: 166 IILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLH 225 ++ AY + GGF AV WTD VQ + M LI++PI+ GG I SVDP+ + Sbjct: 128 GVVVAYTLFGGFLAVSWTDFVQGIIMFAALILVPIVTFFHTGGAGDTVAEIRSVDPDMFN 187 Query: 226 PFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLW 285 F G +++ I +W +GY GQPHI+ R+M++ ++++R G W + Sbjct: 188 IFKG----TSVLGIISLFAWGLGYFGQPHIIVRFMAITSVKEIKRARRIGMG-WMILSAV 242 Query: 286 GAFFAGFLGFALVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLL 345 GA G G A + ++DPE I + + GF+I+ I++A+MST SQLL Sbjct: 243 GAVLTGLGGIAYYHQRGMTLKDPETIFIQLGNILFHPIITGFLISAILAAIMSTISSQLL 302 Query: 346 VASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGG 405 V SS++ D+Y + + K++V + R+ V AV++VA+ A I +V+ AW G Sbjct: 303 VTSSSLVEDLYKSMFRRSASDKELVFLGRLAVLAVSIVALVLAWEKNNTILGLVSYAWAG 362 Query: 406 LAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQW 465 FGP++ LSL+WKR+TK + GM G + +I WA N F Sbjct: 363 FGASFGPVVLLSLFWKRMTKWGALAGMIVGAATVII-------WA-NAGLSDFL------ 408 Query: 466 FNGVPVFFINFFVTLFIIIIVSLLTKPPEDVV 497 + +P F +L + VS+LT+ P V Sbjct: 409 YEMIP----GFAASLLSVFFVSILTQAPSQAV 436 >gb|AAG19342.1| (AE005029) proline permease; PutP [Halobacterium sp. NRC-1] Length = 522 Score = 277 bits (700), Expect = 3e-73 Identities = 162/470 (34%), Positives = 250/470 (52%), Gaps = 22/470 (4%) Query: 33 YFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIG 92 Y +GGR V + S++AS+ SGWL LG PG A+ G+ AF+ G+G + LA + + Sbjct: 7 YVIGGRDVGPVVTGFSERASEMSGWLTLGVPGDAYTTGIMAFYNGVGMIPADLAAWAGLA 66 Query: 93 PRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQA 152 RLR Y+ RA+TLP + RL D+T +++ +S+ +++VF +YV AQ A G Sbjct: 67 KRLRKYSEIVRAVTLPTFFATRLNDDTGVVKAVSSFVLIVFEGSYVGAQIVAAGTLLRVL 126 Query: 153 FNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRA 212 V + GI+ +I+ Y + GG+FAV W+D Q +L I+PI+A GL A Sbjct: 127 TGVDMWVGIVAGGVIVVGYTMLGGYFAVAWSDYFQGAIILAAFAILPIIAYA-TWGLPFA 185 Query: 213 TQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPG 272 + GGATGWAA+ I YA+ +G G PHI+ R+M ++ R +R Sbjct: 186 DLAAMDNGASLTSITGGATGWAALFGIISYAAVGLGIPGNPHIMVRFMGIDRVRNVRTAA 245 Query: 273 IFISGIWTTIVLWGAFFAGFLGFALVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGI 332 + ++ ++ + GA G +AL G + E+ + +P + + LP VAG V+A Sbjct: 246 V-VAQLFMFVAYIGAALVGL--YALTQFGGL--ENTDNAMPLVTLELLPSAVAGVVLAAA 300 Query: 333 ISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGP 392 ++A+MS+ADSQLLVA+SA+ D+YH L ++ + Q+V SR V A+ ++ FA Sbjct: 301 LAAMMSSADSQLLVATSAVVEDVYHGFLNEQATEAQLVRYSRYVTLAIGFASIGFAYVAR 360 Query: 393 KV-IYQMVAT-AWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVILE--AKIYG 448 IY++V AWGGL GP+L LWW+RVT + M G + ++ I G Sbjct: 361 NTPIYELVLNYAWGGLGAALGPLLIAVLWWRRVTAAGAVASMVTGTATMILWTQWPTILG 420 Query: 449 ----WAFNPKAPGFFGTLGQWFNGVPVFFINFFVTLFIIIIVSLLTKPPE 494 +F+P G G F F V+ ++++VSLLT PP+ Sbjct: 421 PETVNSFHPAVSGMLTVYG--------LFPAFVVSAVVLVVVSLLTTPPD 462 >sp|P45174|PUTP_HAEIN SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE) >gi|1075316|pir||E64118 sodium/proline symporter - Haemophilus influenzae (strain Rd KW20) >gi|1574814|gb|AAC22999.1| (U32814) sodium/proline symporter (proline permease) (putP) [Haemophilus influenzae Rd] Length = 504 Score = 275 bits (697), Expect = 7e-73 Identities = 159/505 (31%), Positives = 250/505 (49%), Gaps = 19/505 (3%) Query: 6 LFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65 L F IY+ + IG A YT Y +GGR++ +S ASD SGWL++G PG+ Sbjct: 8 LITFTIYIFGMLLIGVLAYYYTNNLSDYILGGRRLGSFVTAMSAGASDMSGWLLMGLPGA 67 Query: 66 AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIRI 124 + +GL W IG G ++LL+ RLR+Y A+TLP+Y R + KL+++ Sbjct: 68 VYLSGLVEGWIAIGLTIGAYFNWLLVAGRLRVYTELNNNALTLPEYFHNRFGSSHKLLKL 127 Query: 125 LSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTD 184 +SA IILVF+T Y A+ AG K F F+V +T + AY GGF AV WTD Sbjct: 128 VSATIILVFLTIYCASGVVAGAKLFQNIFSVEYSTALWYGAAATIAYTFIGGFLAVSWTD 187 Query: 185 VVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYAS 244 +QA M+ LI+ P+ L+ + + ++ + F + + A+ Sbjct: 188 TIQATLMIFALILTPVFVLLSFADTAQFSAVLEQAEAAVNKDFTDLFTSTTPLGLLSLAA 247 Query: 245 WIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLG----FALVAS 300 W +GY GQPHI+ R+M+ + + L + G W + L GA G FA A Sbjct: 248 WGLGYFGQPHILARFMAADSVKSLIKARRISMG-WMVLCLAGAIGIGLFAIPYFFANPAI 306 Query: 301 GSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVL 360 +PE++ +A W+AG +++ I++AVMST +QLL++SS+I D Y + Sbjct: 307 AGTVNREPEQVFIELAKLLFNPWIAGILLSAILAAVMSTLSAQLLISSSSITEDFYKGFI 366 Query: 361 GQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWW 420 +K++V + RI+V +A +A+W A + ++V AW G FGP++ SL+W Sbjct: 367 RPNASEKELVWLGRIMVLVIAALAIWIAQDENSKVLKLVEFAWAGFGSAFGPVVLFSLFW 426 Query: 421 KRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTL 480 KR+T + GM G ++ ++ W A WF + F +L Sbjct: 427 KRMTSSGAMAGMLVGAVT-------VFAWKEVVPAD------TDWFKVYEMIPGFAFASL 473 Query: 481 FIIIIVSLLTKPPEDVVKLHEELFK 505 II+I L KP +D++ ++ K Sbjct: 474 AIIVISLLSNKPEQDILNTFDKAEK 498 >emb|CAA70363.1| (Y09163) proline transport system [Corynebacterium glutamicum] Length = 524 Score = 266 bits (673), Expect = 4e-70 Identities = 163/533 (30%), Positives = 260/533 (48%), Gaps = 38/533 (7%) Query: 2 NFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLG 61 N + +IY++++ IG+W+ + T+ D Y + GR ++ A +S ASD SGWL++G Sbjct: 4 NTWFIIAIVIYMLVMVLIGYWSYRKTEKYDDYMLAGRGLNPFVAAMSAGASDMSGWLLMG 63 Query: 62 YPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDNTK 120 PG+ F G+ W +G G A+++ + PRLR Y+ +ITLP + E RL+D ++ Sbjct: 64 LPGALFVTGMSELWIAVGLTIGAWANWMWVAPRLRSYSEISANSITLPSFFENRLRDKSR 123 Query: 121 LIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAV 180 +RI++A II+VF T Y+++ AGG + F G+ I + Y GGF AV Sbjct: 124 ALRIIAALIIIVFFTFYISSGMVAGGVYWESTFGGDYLLGMAIVAGVTVLYTFIGGFLAV 183 Query: 181 VWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHP----FGGATGWAAI 236 +TD VQ M +LII+P++A L I + + N P G T ++ I Sbjct: 184 SYTDAVQGTIMFFSLIIVPVMAYF---ALANPMDIWSFANSNDYGPHTDGIGNPTYFSMI 240 Query: 237 -----VFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAG 291 IG W +GY GQPHIV R+M++ P + ++ G I W I L GA F Sbjct: 241 SGISAAAIIGNLGWGLGYFGQPHIVVRFMALRTPAEAKQ-GRRIGISWMIICLIGATFTA 299 Query: 292 FLGFALVASG-SIKVEDP---ERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVA 347 + A + D E I +A +AG ++ +++A+MST SQLLV Sbjct: 300 IISTVFFAQNPDANITDTRAYESIFLDLARMLFHPLIAGLILTAVLAAIMSTMSSQLLVT 359 Query: 348 SSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLA 407 +S++ D+ V L ++ ++ +SR V +A++A AI I +V AW G Sbjct: 360 ASSLIEDLLKVVKKDSLSERTLIMLSRATVIILAIIAAAMAINPSDSILGLVGFAWAGFG 419 Query: 408 VGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFN 467 FGPI+ SL+WKR+ I GM G I + W +P + + + Sbjct: 420 SAFGPIILASLYWKRLNAAGAISGMITGAIVSI-------AWGMSPLSDTLYEIIP---- 468 Query: 468 GVPVFFINFFVTLFIIIIVSLLTKPPEDVVKLHEELFKKV--PIEKSEKIKTA 518 F + ++++VSLLTK P + + E K + +E +E + A Sbjct: 469 -------GFALATIVMVVVSLLTKEPSEEILNEFETAKDLAAAVESNEDVDFA 514 >pir||E75138 osmoregulated proline transporter PAB0609 - Pyrococcus abyssi (strain Orsay) >gi|5458333|emb|CAB49822.1| (AJ248285) OSMOREGULATED PROLINE TRANSPORTER [Pyrococcus abyssi] Length = 484 Score = 255 bits (644), Expect = 1e-66 Identities = 161/501 (32%), Positives = 254/501 (50%), Gaps = 39/501 (7%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 IL + YL L +G + + K+ + + GR++ A LS++A+ S W +LG PG Sbjct: 7 ILAVLVFYLGFLISVGIYQGRKAKSHKDFSIAGRQLPGWVAALSERATGESAWCLLGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRI 124 AF AGL A W IGC+ G + + + RLR A K+ A+T DY+ R + K IRI Sbjct: 67 FAFAAGLAAIWPAIGCVLGIIVAWAVFAGRLRKEAEKYDAVTFVDYIAKRHPEAEKWIRI 126 Query: 125 LSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTD 184 L +A I F YV AQ+ GGK F + G+LIT +++ Y + GG +V +TD Sbjct: 127 LGSATIAFFFFFYVGAQYLGGGKVLNTLFGLDPKLGMLITALVILPYTVMGGLKSVAYTD 186 Query: 185 VVQAMFMLLTLIIMPILALVEIGGLDR--ATQIIASVDPNKLH---PFGGATGWAAIVFA 239 VQA+ M+LTLI+ PI+ ++ I AT + A++ + GG G AAIVF Sbjct: 187 TVQAIVMILTLIVAPIVGVIYIANHPELYATSVTAALSKAGVKYSTILGGMAGAAAIVFV 246 Query: 240 IGYASWIVGYL-GQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALV 298 I SW GYL G P + R+M+++D + + G WT I GA G++G A+ Sbjct: 247 IAEFSWFFGYLGGMPQLSIRFMAIKDDKNAKLARNIGIG-WTIIAYIGALMIGWIGIAIF 305 Query: 299 ASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHK 358 +K DPE+++P++ + P +A I G ++A++STADS L+++S+ + +I Sbjct: 306 GPNGLK--DPEQVMPSVMLKLFPPALAAVFITGAVAAMLSTADSLLILSSTEFSENILKP 363 Query: 359 -VLGQELGKKQMVNISRIVVAAVALVAMWFAITGPK-VIYQMVATAWGGLAVGFGPILTL 416 + E ++ + +SR+ ++ ++A+ A P +IY +V W G+ F I+ L Sbjct: 364 YIYKNEADPRKSLMVSRLTTVSLGIIALIMAYVVPSHLIYTIVGYTWAGIGDTFSVIVIL 423 Query: 417 SLWWKRVTKEAGIVGMAYGLISEVI-----LEAKIYGWAFNPKAPGFFGTLGQWFNGVPV 471 +L+WKR +A + GL+ V L+AK V V Sbjct: 424 TLFWKRFHGKAVPPTIIAGLLFTVFWISSGLDAK-----------------------VSV 460 Query: 472 FFINFFVTLFIIIIVSLLTKP 492 +NF VT + II + KP Sbjct: 461 RLMNFIVTFIVAIIATYAIKP 481 >pir||C69115 sodium/proline symporter (proline permease) - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622992|gb|AAB86322.1| (AE000938) sodium/proline symporter (proline permease) [Methanobacterium thermoautotrophicum] Length = 526 Score = 191 bits (481), Expect = 1e-47 Identities = 134/521 (25%), Positives = 239/521 (45%), Gaps = 50/521 (9%) Query: 10 LIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKA 69 LIY +++ Y+G+ A + T+T + Y V GR+ H +S A+ S ++G+ G A Sbjct: 11 LIYFLLVGYVGYVAWRRTETSEDYMVAGRRTHPYIMAMSYGATFISTAAIVGFGGMAGVF 70 Query: 70 GLGAFW-AGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAA 128 G+G W + L G ++ G R A+T P++L R N++ ++ A Sbjct: 71 GMGILWLVFLNILVGIFIAFVFFGKRTMKMGHNMSALTFPEFLGRRF--NSRFLQYFGGA 128 Query: 129 IILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQA 188 II + M Y + + + + +++ +I+ YV+ GG V++TD +Q Sbjct: 129 IIFLGMPLYASVVLIGAARFIETTLGLDFSIALILMAVIVAVYVVLGGIRGVMYTDALQG 188 Query: 189 MFMLLTLIIMPILALVEIGGLDRATQIIASVD---PNKLHPFGGATGW------------ 233 M L +I + + +GG+ A Q + ++ P K GATGW Sbjct: 189 TIMFLGMIFLVVSTYYLLGGVVDAHQALTNISHLIPAKARAI-GATGWTSMPLYGSPYWW 247 Query: 234 ---AAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFA 290 + I+ +G VG L QP ++ R+M+V+ R+L R G+ I ++ ++ W A+ Sbjct: 248 TLLSTIILGVG-----VGVLAQPQLIVRFMTVKSNRELNR-GVLIGALFIFVMTWSAYVV 301 Query: 291 GFLG--FALVASGSIKVE----DPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQL 344 G L + G I V+ + ++I+P +P W + + ++SA MST +Q Sbjct: 302 GALSNVYFFRKMGMIAVQAAGGNADKIIPFFIKSAMPEWFSYIFMLTLLSAAMSTLSAQF 361 Query: 345 LVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWG 404 V +AI RD+Y V ++ + ++ I++A + V + + + G ++ Q A +G Sbjct: 362 HVQGTAIGRDVYETVRRRKGDRSVLITRGGIIIAVLIAVVLGYLLPG-SIVAQGTALFFG 420 Query: 405 GLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQ 464 A F + +++WKR T++ I GM G I V L ++ + +A G L Sbjct: 421 ICAASFLSVYVAAIFWKRATRQGAIAGMVSGAI--VSLFWLLFEYKKTAEALGIAKAL-- 476 Query: 465 WFNG----------VPVFFINFFVTLFIIIIVSLLTKPPED 495 F G V + V+ ++ VSLLT+PP D Sbjct: 477 -FGGPVIASMPWPVVDPILVGVPVSAIFMVAVSLLTEPPSD 516 >pir||D65118 pantothenate permease [validated] - Escherichia coli >gi|606198|gb|AAA58061.1| (U18997) pantothenate permease [Escherichia coli] >gi|1789656|gb|AAC76290.1| (AE000404) sodium/pantothenate symporter [Escherichia coli K12] Length = 485 Score = 184 bits (462), Expect = 2e-45 Identities = 133/473 (28%), Positives = 234/473 (49%), Gaps = 24/473 (5%) Query: 1 MNFGILFGFLIYLVILAYIGWWANKYTKTE---DQYFVGGRKVHVLAATLSDKASDFSGW 57 M ++ + YLV++ I +A + T ++YF+G R + + ++ A+ S Sbjct: 3 MQLEVILPLVAYLVVVFGISVYAMRKRSTGTFLNEYFLGSRSMGGIVLAMTLTATYISAS 62 Query: 58 LMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKD 117 +G PG+A+K GLG + L ++G + I A ++ A+TL D L AR + Sbjct: 63 SFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILARRYNAVTLNDMLFARYQ- 121 Query: 118 NTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGF 177 ++L+ L++ +LV + QF G + A + TG+LI I + Y GGF Sbjct: 122 -SRLLVWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYETGLLIFGISIALYTAFGGF 180 Query: 178 FAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIV 237 A V D +Q + ML+ +++ I + GGL A Q + ++DP + P GA + Sbjct: 181 RASVLNDTMQGLVMLIGTVVLLIGVVHAAGGLSNAVQTLQTIDPQLVTP-QGADDILSPA 239 Query: 238 FAIGYASWIV---GYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLG 294 F + W++ G +G PH R +S +D + + R GI I I I+++G AG LG Sbjct: 240 FMTSF--WVLVCFGVIGLPHTAVRCISYKDSKAVHR-GIIIGTIVVAILMFGMHLAGALG 296 Query: 295 FALVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARD 354 A++ ++ P+ ++P + + LP + AG +A ++A+MST ++QLL +S+ I +D Sbjct: 297 RAVIPDLTV----PDLVIPTLMVKVLPPFAAGIFLAAPMAAIMSTINAQLLQSSATIIKD 352 Query: 355 IYHKV----LGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGF 410 +Y + + E K+M + +V+ A+ L+A W P++I + A+GGL F Sbjct: 353 LYLNIRPDQMQNETRLKRMSAVITLVLGALLLLAAW---KPPEMIIWLNLLAFGGLEAVF 409 Query: 411 GPILTLSLWWKRVTKEAGIVGMAY-GLISEVILEAKIYGWAFNPKAPGFFGTL 462 L L L+W+R + + M G++ V+ I F+P P +L Sbjct: 410 LWPLVLGLYWERANAKGALSAMIVGGVLYAVLATLNIQYLGFHPIVPSLLLSL 462 >sp|P16256|PANF_ECOLI SODIUM/PANTOTHENATE SYMPORTER (PANTOTHENATE PERMEASE) Length = 483 Score = 184 bits (462), Expect = 2e-45 Identities = 133/473 (28%), Positives = 234/473 (49%), Gaps = 24/473 (5%) Query: 1 MNFGILFGFLIYLVILAYIGWWANKYTKTE---DQYFVGGRKVHVLAATLSDKASDFSGW 57 M ++ + YLV++ I +A + T ++YF+G R + + ++ A+ S Sbjct: 1 MQLEVILPLVAYLVVVFGISVYAMRKRSTGTFLNEYFLGSRSMGGIVLAMTLTATYISAS 60 Query: 58 LMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKD 117 +G PG+A+K GLG + L ++G + I A ++ A+TL D L AR + Sbjct: 61 SFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILARRYNAVTLNDMLFARYQ- 119 Query: 118 NTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGF 177 ++L+ L++ +LV + QF G + A + TG+LI I + Y GGF Sbjct: 120 -SRLLVWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYETGLLIFGISIALYTAFGGF 178 Query: 178 FAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIV 237 A V D +Q + ML+ +++ I + GGL A Q + ++DP + P GA + Sbjct: 179 RASVLNDTMQGLVMLIGTVVLLIGVVHAAGGLSNAVQTLQTIDPQLVTP-QGADDILSPA 237 Query: 238 FAIGYASWIV---GYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLG 294 F + W++ G +G PH R +S +D + + R GI I I I+++G AG LG Sbjct: 238 FMTSF--WVLVCFGVIGLPHTAVRCISYKDSKAVHR-GIIIGTIVVAILMFGMHLAGALG 294 Query: 295 FALVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARD 354 A++ ++ P+ ++P + + LP + AG +A ++A+MST ++QLL +S+ I +D Sbjct: 295 RAVIPDLTV----PDLVIPTLMVKVLPPFAAGIFLAAPMAAIMSTINAQLLQSSATIIKD 350 Query: 355 IYHKV----LGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGF 410 +Y + + E K+M + +V+ A+ L+A W P++I + A+GGL F Sbjct: 351 LYLNIRPDQMQNETRLKRMSAVITLVLGALLLLAAW---KPPEMIIWLNLLAFGGLEAVF 407 Query: 411 GPILTLSLWWKRVTKEAGIVGMAY-GLISEVILEAKIYGWAFNPKAPGFFGTL 462 L L L+W+R + + M G++ V+ I F+P P +L Sbjct: 408 LWPLVLGLYWERANAKGALSAMIVGGVLYAVLATLNIQYLGFHPIVPSLLLSL 460 >sp|P44963|PANF_HAEIN SODIUM/PANTOTHENATE SYMPORTER (PANTOTHENATE PERMEASE) >gi|1075105|pir||H64105 pantothenate transport protein - Haemophilus influenzae (strain Rd KW20) >gi|1574003|gb|AAC22634.1| (U32778) sodium/pantothenate symporter (panF) [Haemophilus influenzae Rd] Length = 484 Score = 180 bits (452), Expect = 4e-44 Identities = 130/464 (28%), Positives = 223/464 (48%), Gaps = 47/464 (10%) Query: 1 MNFGILFGFLIYLV------ILAYIGWWANKYTKTE--DQYFVGGRKVHVLAATLSDKAS 52 MN GI+ +IYL I AY+ K TK + +Y+VG R + ++ ++ Sbjct: 1 MNLGIILPLIIYLTFVFGAAIFAYV-----KRTKGDFLTEYYVGNRSMTGFVLAMTTAST 55 Query: 53 DFSGWLMLGYPGSAFKAGLG----------AFWAGIGCLFGTLADYLLIGPRLRIYAGKF 102 S +G PG+A+K GLG W +G L G + + + + Sbjct: 56 YASASSFVGGPGAAYKYGLGWVLLAMIQVPVVWLALGAL----------GKKFALLSRET 105 Query: 103 RAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGIL 162 A+T+ D R K N L+ + S A++L F A + QF G + +S T +L Sbjct: 106 NALTINDLFFYRYK-NKYLVWLSSLALLLAFFAA-MTVQFIGGARLLETTIGISYTQALL 163 Query: 163 ITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPN 222 + + + Y GGF AVV TD +Q M+ II+ I + +GG++ A + +DP+ Sbjct: 164 LFALTVGIYTFIGGFRAVVLTDTIQGTVMIFGTIILLIGTIYALGGVESAVNKLTEIDPD 223 Query: 223 KLHPFGGATGWAAIVFAIGYASWIV---GYLGQPHIVTRYMSVEDPRKLRRPGIFISGIW 279 + P+ G G F + WI+ G +G PH R M+ +D + L R G+ I I Sbjct: 224 LVTPY-GPNGMLDFQFMASF--WILVCFGVVGLPHTAVRCMAFKDSKALHR-GMLIGTIV 279 Query: 280 TTIVLWGAFFAGFLGFALVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMST 339 +I++ G AG LG A++ + ++ ++++P + I LP VAG +A +SA+MST Sbjct: 280 LSIIMLGMHLAGALGRAVIPNLTVS----DQVIPTLMIKVLPPIVAGIFLAAPMSAIMST 335 Query: 340 ADSQLLVASSAIARDIYHKVLGQEL-GKKQMVNISRIVVAAVALVAMWFAITGPKVIYQM 398 D+QL+ +SS +D+Y + +K++ S I+ + + ++ A+ P +I + Sbjct: 336 IDAQLIQSSSIFVKDLYLSAKPEAAKNEKKVSYFSSIITLILTALLIFAALNPPDMIIWL 395 Query: 399 VATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVIL 442 A+GGL F ++ L ++W + + M GL S ++L Sbjct: 396 NLFAFGGLEAAFLWVIVLGIYWDKANAYGALSSMIIGLGSYILL 439 >gb|AAF45263.1| (AF230602) proline permease [Escherichia coli] >gi|7288753|gb|AAF45265.1| (AF230604) proline permease [Escherichia coli] >gi|7288757|gb|AAF45267.1| (AF230606) proline permease [Escherichia coli] >gi|7288765|gb|AAF45271.1| (AF230610) proline permease [Escherichia coli] >gi|7288769|gb|AAF45273.1| (AF230612) proline permease [Escherichia coli] >gi|7288771|gb|AAF45274.1| (AF230613) proline permease [Escherichia coli] >gi|7288773|gb|AAF45275.1| (AF230614) proline permease [Escherichia coli] >gi|7288775|gb|AAF45276.1| (AF230615) proline permease [Escherichia coli] >gi|7288777|gb|AAF45277.1| (AF230616) proline permease [Escherichia coli] >gi|7288779|gb|AAF45278.1| (AF230617) proline permease [Escherichia coli] >gi|7288781|gb|AAF45279.1| (AF230618) proline permease [Escherichia coli] >gi|7288785|gb|AAF45281.1| (AF230620) proline permease [Escherichia coli] >gi|7288787|gb|AAF45282.1| (AF230621) proline permease [Escherichia coli] >gi|7288791|gb|AAF45284.1| (AF230623) proline permease [Escherichia coli] >gi|7288797|gb|AAF45287.1| (AF230626) proline permease [Escherichia coli] >gi|7288799|gb|AAF45288.1| (AF230627) proline permease [Escherichia coli] >gi|7288801|gb|AAF45289.1| (AF230628) proline permease [Escherichia coli] >gi|7288803|gb|AAF45290.1| (AF230629) proline permease [Escherichia coli] >gi|7288805|gb|AAF45291.1| (AF230630) proline permease [Escherichia coli] >gi|7288807|gb|AAF45292.1| (AF230631) proline permease [Escherichia coli] >gi|7288809|gb|AAF45293.1| (AF230632) proline permease [Escherichia coli] >gi|7288811|gb|AAF45294.1| (AF230633) proline permease [Escherichia coli] >gi|7288813|gb|AAF45295.1| (AF230634) proline permease [Escherichia coli] >gi|7288815|gb|AAF45296.1| (AF230635) proline permease [Escherichia coli] Length = 232 Score = 171 bits (428), Expect = 2e-41 Identities = 84/234 (35%), Positives = 128/234 (53%), Gaps = 5/234 (2%) Query: 31 DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLL 90 D Y +GGR + LS ASD SGWL++G PG+ F +G+ W IG G ++ L Sbjct: 2 DDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKL 61 Query: 91 IGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTF 149 + RLR++ A+TLPDY R +D ++++RI+SA +IL+F T Y A+ AG + F Sbjct: 62 VAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLF 121 Query: 150 AQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGL 209 F +S T + Y GGF AV WTD VQA M+ LI+ P++ ++ +GG Sbjct: 122 ESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGF 181 Query: 210 DRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVE 263 + ++I + G + AI+ +G W +GY GQPHI+ R+M+ + Sbjct: 182 GDSLEVIKQKSIENVDMLKG-LNFVAIISLMG---WGLGYFGQPHILARFMAAD 231 >gb|AAF45280.1| (AF230619) proline permease [Escherichia coli] Length = 232 Score = 171 bits (428), Expect = 2e-41 Identities = 84/234 (35%), Positives = 128/234 (53%), Gaps = 5/234 (2%) Query: 31 DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLL 90 D Y +GGR + LS ASD SGWL++G PG+ F +G+ W IG G ++ L Sbjct: 2 DDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKL 61 Query: 91 IGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTF 149 + RLR++ A+TLPDY R +D ++++RI+SA +IL+F T Y A+ AG + F Sbjct: 62 VAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLF 121 Query: 150 AQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGL 209 F +S T + Y GGF AV WTD VQA M+ LI+ P++ ++ +GG Sbjct: 122 ESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGF 181 Query: 210 DRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVE 263 + ++I + G + AI+ +G W +GY GQPHI+ R+M+ + Sbjct: 182 GDSLEVIKQKSIENVDMLKG-LNFVAIISLMG---WGLGYFGQPHILARFMAAD 231 >gb|AAF45283.1| (AF230622) proline permease [Escherichia coli] Length = 232 Score = 171 bits (428), Expect = 2e-41 Identities = 84/234 (35%), Positives = 128/234 (53%), Gaps = 5/234 (2%) Query: 31 DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLL 90 D Y +GGR + LS ASD SGWL++G PG+ F +G+ W IG G ++ L Sbjct: 2 DDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKL 61 Query: 91 IGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTF 149 + RLR++ A+TLPDY R +D ++++RI+SA +IL+F T Y A+ AG + F Sbjct: 62 VAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLF 121 Query: 150 AQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGL 209 F +S T + Y GGF AV WTD VQA M+ LI+ P++ ++ +GG Sbjct: 122 ESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGF 181 Query: 210 DRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVE 263 + ++I + G + AI+ +G W +GY GQPHI+ R+M+ + Sbjct: 182 GDSLEVIKQKSIENVDMLKG-LNFVAIISLMG---WGLGYFGQPHILARFMAAD 231 >gb|AAF45285.1| (AF230624) proline permease [Escherichia coli] Length = 232 Score = 171 bits (428), Expect = 2e-41 Identities = 84/234 (35%), Positives = 128/234 (53%), Gaps = 5/234 (2%) Query: 31 DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLL 90 D Y +GGR + LS ASD SGWL++G PG+ F +G+ W IG G ++ L Sbjct: 2 DDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKL 61 Query: 91 IGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTF 149 + RLR++ A+TLPDY R +D ++++RI+SA +IL+F T Y A+ AG + F Sbjct: 62 VAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLF 121 Query: 150 AQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGL 209 F +S T + Y GGF AV WTD VQA M+ LI+ P++ ++ +GG Sbjct: 122 ESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGF 181 Query: 210 DRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVE 263 + ++I + G + AI+ +G W +GY GQPHI+ R+M+ + Sbjct: 182 GDSLEVIKQKSIENVDMLKG-LNFVAIISLMG---WGMGYFGQPHILARFMAAD 231 >gb|AAF45264.1| (AF230603) proline permease [Escherichia coli] >gi|7288755|gb|AAF45266.1| (AF230605) proline permease [Escherichia coli] >gi|7288759|gb|AAF45268.1| (AF230607) proline permease [Escherichia coli] >gi|7288761|gb|AAF45269.1| (AF230608) proline permease [Escherichia coli] >gi|7288763|gb|AAF45270.1| (AF230609) proline permease [Escherichia coli] >gi|7288767|gb|AAF45272.1| (AF230611) proline permease [Escherichia coli] Length = 232 Score = 170 bits (426), Expect = 4e-41 Identities = 84/232 (36%), Positives = 127/232 (54%), Gaps = 5/232 (2%) Query: 31 DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLL 90 D Y +GGR + LS ASD SGWL++G PG+ F +G+ W IG G ++ L Sbjct: 2 DDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKL 61 Query: 91 IGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTF 149 + RLR++ A+TLPDY R +D ++++RI+SA +IL+F T Y A+ AG + F Sbjct: 62 VAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLF 121 Query: 150 AQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGL 209 F +S T + Y GGF AV WTD VQA M+ LI+ P++ ++ +GG Sbjct: 122 ESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGF 181 Query: 210 DRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMS 261 + ++I + G + AI+ +G W +GY GQPHI+ R+M+ Sbjct: 182 GDSLEVIKQKSIENVDMLKG-LNFVAIISLMG---WGLGYFGQPHILARFMA 229 >gb|AAF45286.1| (AF230625) proline permease [Escherichia coli] Length = 232 Score = 168 bits (422), Expect = 1e-40 Identities = 83/234 (35%), Positives = 128/234 (54%), Gaps = 5/234 (2%) Query: 31 DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLL 90 D Y +GGR + LS ASD SGWL++G PG+ F +G+ W IG G ++ L Sbjct: 2 DDYILGGRSLGPFVTALSVGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKL 61 Query: 91 IGPRLRIYAG-KFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTF 149 + RLR++ A+TLP+Y R +D ++++RI+SA +IL+F T Y A+ AG + F Sbjct: 62 VAGRLRVHTEYNNNALTLPNYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLF 121 Query: 150 AQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGL 209 F +S T + Y GGF AV WTD VQA M+ LI+ P++ ++ +GG Sbjct: 122 ESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGF 181 Query: 210 DRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVE 263 + ++I + G + AI+ +G W +GY GQPHI+ R+M+ + Sbjct: 182 GDSLEVIKQKSIENVDMLKG-LNFVAIISLMG---WGLGYFGQPHILARFMAAD 231 >gi|11497636 proline permease (putP-1) [Archaeoglobus fulgidus] >gi|7442766|pir||G69251 proline permease (putP-1) homolog - Archaeoglobus fulgidus >gi|2650635|gb|AAB91210.1| (AE001105) proline permease (putP-1) [Archaeoglobus fulgidus] Length = 491 Score = 163 bits (409), Expect = 4e-39 Identities = 129/490 (26%), Positives = 217/490 (43%), Gaps = 34/490 (6%) Query: 10 LIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDF-SGWLMLGYPGSAFK 68 L Y V+ +G++A + KT + Y+ G RK+ + T S S + +G PG + Sbjct: 11 LAYFVVTLALGFFAARKIKTAEHYY-GARKLFGMFVTAVAVFSGIASAFTFIGGPGLVYP 69 Query: 69 AGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAA 128 G W + + L+G R+++ TLPD AR K + +R L+A Sbjct: 70 MGGTVNWVIWTPVISMPLIWYLLGKRIKLITEARPVATLPDLTAARFKSDA--VRFLTAV 127 Query: 129 IILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQA 188 ++ + Y+A G + I I I+ Y GG A + TD Q Sbjct: 128 ALIFGIITYLAGNVMGAGLVLTDMLGTPLELSIAIVFGIIMLYTAFGGMVASILTDFFQG 187 Query: 189 MFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASW--- 245 + M++ II + L+ GG++ IA +P + P G W +G W Sbjct: 188 LVMMVAAIIFVVFILIMTGGVENLFATIAESNPRHIDPIGVGPIW------LGIMGWWWA 241 Query: 246 -IVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWT-TIVLWGAFFAGFLGFALVASGSI 303 +G QPH VT++ +++D R L+ + + WT ++W FF G+ +V G Sbjct: 242 LNIGSSVQPHAVTKFFALKDYRDLKWGALVTTIAWTLACLMW--FFGGYASVWVVIKG-- 297 Query: 304 KVEDPERIVPAM--AIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLG 361 E P R A+ I +P + + AG+++A+MST + + ++A+ RDI +G Sbjct: 298 LAEAPARSDQAIFGVIAQMPVVLKAVIYAGVLAAIMSTVSGFISMGTAAVVRDI-PTAIG 356 Query: 362 QELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWK 421 + L ++ + R+V + +VA F G V+ +V G A P+L + L WK Sbjct: 357 KSLSQRGQILWGRVVTVILTVVAALFGYYGGYVVGILVTLGLGYFASMLFPLLVIGLNWK 416 Query: 422 RVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTLF 481 R TKEA I+ A L + L +Y + P G+P + + F V + Sbjct: 417 RATKEAAIITTA--LTVAMNLGFLVYEKVLSMSLP----------YGLPGYGVTFAVGII 464 Query: 482 IIIIVSLLTK 491 +++VSL+TK Sbjct: 465 TMVLVSLITK 474 >pir||JU0296 pantothenate permease - Escherichia coli >gi|147067|gb|AAA24276.1| (M30953) pantothenate permease (panF) [Escherichia coli] Length = 482 Score = 153 bits (384), Expect = 3e-36 Identities = 127/476 (26%), Positives = 222/476 (45%), Gaps = 31/476 (6%) Query: 1 MNFGILFGFLIYLVILAYIGWWANKYTKTE---DQYFVGGRKVHVLAATLSDKASDFSGW 57 M ++ + YLV++ I +A + T ++YF+G R + + ++ A+ S Sbjct: 1 MQLEVILPLVAYLVVVFGISVYAMRKRSTGTFLNEYFLGSRSMGGIVLAMTLTATYISAS 60 Query: 58 LMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKD 117 +G PG+A+K GLG + L ++G + I A ++ A+TL D L AR + Sbjct: 61 SFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILARRYNAVTLNDMLFARYQ- 119 Query: 118 NTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGF 177 ++L+ L++ +LV + QF G + A + TG+LI I + Y GGF Sbjct: 120 -SRLLVWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYETGLLIFGISIALYTAFGGF 178 Query: 178 FAVVWTDVVQAM---FMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWA 234 +A + A GGL A Q + ++DP + P GA Sbjct: 179 APAAERHHARACDADWHRCAAYWRSTCA----GGLSNAVQTLQTIDPQLVTP-QGADDIL 233 Query: 235 AIVFAIGYASWIV---GYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAG 291 + F + W++ G +G H R +S +D + + R GI I I I+++G AG Sbjct: 234 SPAFMTSF--WVLVCFGVIGLAHTAVRCISYKDSKAVHR-GIIIGTIVVAILMFGMHLAG 290 Query: 292 FLGFALVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAI 351 LG A++ + P+ ++P + + LP + AG +A ++A+MST ++QLL +S+ I Sbjct: 291 ALGRAVIPDLHV----PDLVIPTLMVKVLPPFAAGIFLAAPMAAIMSTINAQLLQSSATI 346 Query: 352 ARDIYHKV----LGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLA 407 +D+Y + + E K+M + +V+ A+ L+A W P++I + A+GGL Sbjct: 347 IKDLYLNIRPDQMQNETRLKRMSAVITLVLGALLLLAAW---KPPEMIIWLNLLAFGGLE 403 Query: 408 VGFGPILTLSLWWKRVTKEAGIVGMAY-GLISEVILEAKIYGWAFNPKAPGFFGTL 462 F L L L+W+R + + M G++ V+ I F+P P +L Sbjct: 404 AVFLWPLVLGLYWERANAKGALSAMIVGGVLYAVLATLNIQYLGFHPIVPSLLLSL 459 >pir||E70201 pantothenate permease (panF) homolog - Lyme disease spirochete >gi|2688763|gb|AAC67168.1| (AE001180) pantothenate permease (panF) [Borrelia burgdorferi] Length = 444 Score = 142 bits (354), Expect = 1e-32 Identities = 113/438 (25%), Positives = 209/438 (46%), Gaps = 26/438 (5%) Query: 31 DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLL 90 ++YF+ R ++ + L +S S + P + +K GL + TL +++ Sbjct: 4 NKYFLANRNINFIVMALLFSSSYISASSFISGPSAVYKYGLSFILLATIQIPTTLIVFII 63 Query: 91 IGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTFA 150 +G RL + K AI + DY+ R + + + ++S +++ F ++AQ G K Sbjct: 64 VGQRLNRESKKINAINIIDYIRHRYESD--FLALMSGFVLIFFSMFLISAQLIGGAKLIE 121 Query: 151 QAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLD 210 + + G+ ++ YV GGF AV +TD++Q ML++ +I+ L GG++ Sbjct: 122 VFWGIDYVVGLTFFAFLVFIYVFFGGFKAVAYTDLIQGFLMLVSSVILFSKMLDLGGGIN 181 Query: 211 RATQ-IIASVDPNKLHPFGGATGWAAIVFAIGYASWI---VGYLGQPHIVTRYMSVEDPR 266 + +S+D + L P I+ + WI +G LGQP I+ +++ +D Sbjct: 182 NLFKTATSSLDKSLLLPSNADLKPQYII-----SFWILIGIGILGQPQIINNFIAFKDEN 236 Query: 267 KLRRPGIFISGIWTTIVLWGAFFAGFLG-FALVASGSIKVEDPERIVPAMAIHFLPGWVA 325 ++ F I T I+ + +G FA++ + D ++V +A+ L + Sbjct: 237 AIK----FSLPISTFIISFLIVLMHLIGFFAIILFPDLSPND--KVVLNVALKVLNPFSC 290 Query: 326 GFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAA---VAL 382 G++SA+MST DS LL+ +S + + I+ + ++L K+ V I RI++ + L Sbjct: 291 FMFFIGLLSAIMSTVDSNLLLITSVLIKSIF--IYKEDL--KEDVKIGRIIMISNIFFIL 346 Query: 383 VAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEV-I 441 + + F++ P ++ + A+G L V F PI+ L+ V+K A M GLI + I Sbjct: 347 IILIFSLFPPNFLFFINIFAFGALEVSFFPIIVFGLYLNFVSKIAAFASMFLGLIFYLSI 406 Query: 442 LEAKIYGWAFNPKAPGFF 459 L + W F+P P FF Sbjct: 407 LFFGLNIWFFHPVFPSFF 424 >dbj|BAB07462.1| (AP001519) Na+/solute symporter (Ssf family) [Bacillus halodurans] Length = 554 Score = 141 bits (353), Expect = 1e-32 Identities = 128/499 (25%), Positives = 215/499 (42%), Gaps = 89/499 (17%) Query: 58 LMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKD 117 ++LGY G A+ G W G G LF T L P+LR Y G++ T+P+++ R Sbjct: 68 MILGYDGLAYIMG----WTG-GYLFLTF----LFAPQLRKY-GRY---TVPEFIGDRYGS 114 Query: 118 NTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGF 177 NT R+++A ++ Y+ Q + G + N+ G +I V+++ Y GG Sbjct: 115 NTA--RLIAAIATIIISFTYIIGQLSGSGVVIGRILNIPAMYGTMIGVVVIAIYATLGGM 172 Query: 178 FAVVWTDVVQAMFMLLTLIIMPILALVEIGG--------------LDRATQIIASVDPNK 223 + WT V Q + +++ II + +++ G LD Q + Sbjct: 173 KGITWTQVAQYIILIVAYIIPIVFMSLQLSGNPFPWLTYGNFISQLDGLDQELGL--SQI 230 Query: 224 LHPF--GGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPG----IFISG 277 L PF + + A++F + +VG PH++ R+ +V + R G IFI+ Sbjct: 231 LQPFMESDKSQFIALMFTL-----MVGTAALPHVIVRFYTVTTMKAARWSGAWALIFIAL 285 Query: 278 IWTTIVLWGAFFAGFL-------------------------------GFALVASGSIKVE 306 ++ + + AF L G ++ +++ Sbjct: 286 LYLSAPAYAAFSRFILMTQVANQPIDQLPAWTEAWINTGLLEMADANGDGILQWEELRIS 345 Query: 307 DPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGK 366 + ++ I L +V G V AG ++A +STA L+ SS+ A DIY++++ + Sbjct: 346 NDIVVMATPEIANLGMFVIGLVAAGAMAAALSTAGGLLITISSSFAHDIYYRLMNPKASD 405 Query: 367 KQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTKE 426 ++ + RI + +VA A+ P VI Q+VA A+G F P+L L +WWKR + Sbjct: 406 QKRLLAGRIAIVLATIVAGVVALDPPGVITQIVAWAFGLAGGAFFPVLLLGVWWKRANAK 465 Query: 427 AGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFG--TLGQWFNGVPVFFINFFVTLFIII 484 I GM GL + +Y + FG G GVP V LF+ I Sbjct: 466 GAIAGMLSGLAVTL-----VYIFLARTGTFTLFGIQDTGAGLIGVP-------VNLFVTI 513 Query: 485 IVSLLTKPPEDVVKLHEEL 503 +VSL+T P KL +E+ Sbjct: 514 VVSLMTAAPSQ--KLQDEV 530 >gi|11498674 pantothenate permease (panF-1) [Archaeoglobus fulgidus] >gi|7442768|pir||E69383 pantothenate permease (panF-1) homolog - Archaeoglobus fulgidus >gi|2649519|gb|AAB90171.1| (AE001029) pantothenate permease (panF-1) [Archaeoglobus fulgidus] Length = 491 Score = 139 bits (347), Expect = 7e-32 Identities = 112/468 (23%), Positives = 218/468 (45%), Gaps = 31/468 (6%) Query: 12 YLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGL 71 YL ++ IG + + T+ Y++ G+K+ L + S A+ FS LG G+ F G Sbjct: 10 YLAVVLLIGIYEYRKTRGLLDYYLAGKKLGTLVVSFSFFATYFSTAAFLGGGGTGFLLGF 69 Query: 72 --GAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAAI 129 AF LF LA +++I P ++ A ++ A+T+P+ R +I++A + Sbjct: 70 QWSAFLTFFHVLFAILA-WMVIAPPMKRIADEYGALTIPELFRKRAG---VFSQIVAAVV 125 Query: 130 ILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAM 189 I+ F Y+ + + G ++ TTG++IT +I+ Y GGF AVV TD++Q + Sbjct: 126 IIFFFELYMVSIYKGAGNLLQVMLSMDYTTGLVITAVIVMVYTAIGGFRAVVMTDLIQGV 185 Query: 190 FMLLTLIIMPILALVEIGGLDRATQIIASV------------DPNKLHPFGGATGWAAIV 237 +L+ + + + + +GG A + +++ + K+ P + Sbjct: 186 IVLIGGVALFLTLIYSLGGFSSAIEALSNAKIFGEMVGKALFEIGKVGPPPIVKAGMIVP 245 Query: 238 FAIGYASWI-VGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFA 296 F + I V L P +V R+++ D R + G+ ++ + I F G G+ Sbjct: 246 FVLSLTFAISVAQLASPQLVVRFVAARDSRVIAN-GMILTPLIIGIFAICVFSIGPFGWL 304 Query: 297 LVASGSIKV----EDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIA 352 ++ + V +D + +VP +A+ P + ++ II+A MST +S + + ++A Sbjct: 305 VIPKYTDDVTQFLKDVDLVVPFIAMKLFPAGINALLLTAIIAAAMSTINSLIHLVATAFV 364 Query: 353 RDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGP 412 RD+ V +++ ++ +N++R V A + + FAI VI ++V ++ + F Sbjct: 365 RDLVQNV--KKIEERTALNLTRFAVFIFATIPVIFAINPMGVIVEIVGVSFSVITSAFLV 422 Query: 413 ILTLSLWWKRVTKEAGIVGMAYGLISEVI---LEAKIYGWAFNPKAPG 457 L L+ ++ A M +++ V+ K+Y W + P PG Sbjct: 423 PLIACLYSEKPNSAAISASMVAAVLASVLWYFYYYKVY-WIY-PVVPG 468 >pir||F83241 probable sodium:solute symporter PA3234 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9949356|gb|AAG06622.1|AE004746_6 (AE004746) probable sodium:solute symporter [Pseudomonas aeruginosa] Length = 551 Score = 138 bits (345), Expect = 1e-31 Identities = 122/456 (26%), Positives = 201/456 (43%), Gaps = 28/456 (6%) Query: 1 MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60 +N + F+ ++ I +WA+K ++ Y+ G ++ L+ S L Sbjct: 32 LNVSAIVMFVAFVGATLCITYWASKRNRSAADYYAAGGRITGFQNGLAIAGDYMSAASFL 91 Query: 61 GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTK 120 G F +G IG L G LI RLR GK+ T D RLK K Sbjct: 92 GISALVFTSGYDGLIYSIGFLVGWPIILFLIAERLR-NLGKY---TFADVASYRLKQ--K 145 Query: 121 LIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAV 180 IR LSA LV + Y+ AQ GK F ++ +++ I++ YV+ GG A Sbjct: 146 QIRTLSACGSLVVVAFYLIAQMVGAGKLIELLFGLNYHVAVVLVGILMVLYVLFGGMLAT 205 Query: 181 VWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPF-------GGATGW 233 W +++A+ +L M I+ L + D +T ++ K+HP GG Sbjct: 206 TWVQIIKAVLLLSGASFMAIMVLKHV-NFDVSTLFSEAI---KVHPKGEAIMSPGGLVKD 261 Query: 234 AAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFL 293 F++G+A + G G PHI+ R+ +V D ++ R+ + +G + F GF Sbjct: 262 PISAFSLGFA-LMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYIL-TFIIGFG 319 Query: 294 GFALVASGSIKVEDPERIVPA--MAIHFLPGWVAGFVIAGIISAV-----MSTADSQLLV 346 LV++ + ++ MA L V G + G ISAV ++ L Sbjct: 320 AILLVSTNPDFKDATGALIGGNNMAAVHLADAVGGSLFLGFISAVAFATILAVVAGLTLA 379 Query: 347 ASSAIARDIYHKVL-GQELGKKQMVNISRIVVAAVALVAMWFAITGPKV-IYQMVATAWG 404 +SA++ D+Y V G + +K + +S++ A+ +VA+ I K I MV A+ Sbjct: 380 GASAVSHDLYASVFKGGKANEKDELRVSKMTTVALGVVAIVLGILFEKQNIAFMVGLAFS 439 Query: 405 GLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEV 440 A P+L LS++WK++T ++G GLI+ V Sbjct: 440 IAASCNFPVLLLSMYWKKLTTRGAMIGGWMGLITAV 475 >gi|11498821 proline permease (putP-3) [Archaeoglobus fulgidus] >gi|7483927|pir||E69402 proline permease (putP-3) homolog - Archaeoglobus fulgidus >gi|2649354|gb|AAB90016.1| (AE001019) proline permease (putP-3) [Archaeoglobus fulgidus] Length = 479 Score = 138 bits (343), Expect = 2e-31 Identities = 123/475 (25%), Positives = 210/475 (43%), Gaps = 54/475 (11%) Query: 52 SDFSGWLMLGYPGSAFKAGLGAFWAGI-GCLFGTLADYLLIGPRLRIYAGKFRAITLPDY 110 S FSG ++G G AF G W I G F +LIG +L K +T+ DY Sbjct: 23 SVFSGMTLIGVAGLAFTTGYANVWERIIGPPFAIAFGTILIGYKLFNLKDKNGILTIQDY 82 Query: 111 LEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTA 170 L R D+ K+IRIL+ I V Y+ Q+ A G + G +I +I+ A Sbjct: 83 LAFRY-DDPKIIRILAGLISAVTCFVYLIGQYTAIGVVSYVVLGIPYWLGAVIAAVIVVA 141 Query: 171 YVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGA 230 YV++GG F+ WT +Q++ MLL + + + +GG + Q +A++ + G A Sbjct: 142 YVMSGGMFSTAWTTFLQSILMLLGIYVTVPFIIAWVGGFEAMNQALAAMPEIQNATRGVA 201 Query: 231 TGWAAIVF--------AIGYASWI-----------VGYLGQPHIVTR---YMSVEDPR-- 266 + + ++ A W+ +G + PHIV + +E R Sbjct: 202 ENFMFAKYLSKPFAPASVPLAGWVYNLTLFGITVPLGLMVAPHIVNNMLTFRKIEYTRWG 261 Query: 267 KLRRPGIFISGIWTT----IVLWGAFFAGFLGFALVASGSIKVEDPERIVPAMAIHFLPG 322 L I S I+ T + A+ G + + GSI+V+ + P +A LP Sbjct: 262 PLVMYVIGFSAIFLTALAGMAARVAWAKGMIDIPSLTLGSIEVKWSDMAYPTIASKALPY 321 Query: 323 WVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVAL 382 W+ ++ I++ VMST D +L A++ I+ D+ LG+ L + + ++ +VV + Sbjct: 322 WLFVLLLPTILAGVMSTTDRLILTAANNISYDVLRNALGKNLSENALKKVNMLVVPLIGF 381 Query: 383 VAMWFAITGPKVIYQMVATAWGGLAV----GFGPILTLSLWWKRVTKEAGIVGMAYGLIS 438 ++ A+ +++ + W L++ F PI+ L L+W R+TK A + M G + Sbjct: 382 GSLLIALFPQQLLAWFI---WAALSLMTNCFFFPIM-LGLYWDRMTKNAARLSMIAGFVV 437 Query: 439 EVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFI--NFFVTLFIIIIVSLLTK 491 + A IYG + G+P + + F + + + VSLL K Sbjct: 438 TLATFA-IYGKTI-------------YIAGIPAYSVLPGFVASFVLAVGVSLLEK 478 >gi|11498574 proline permease (putP-2) [Archaeoglobus fulgidus] >gi|7442764|pir||A69371 proline permease (putP-2) homolog - Archaeoglobus fulgidus >gi|2649629|gb|AAB90273.1| (AE001037) proline permease (putP-2) [Archaeoglobus fulgidus] Length = 531 Score = 137 bits (341), Expect = 4e-31 Identities = 130/532 (24%), Positives = 218/532 (40%), Gaps = 47/532 (8%) Query: 10 LIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKA 69 ++Y + + IG+++ + K+ Y+V GR+V + L+ +++ S MLG P F Sbjct: 13 VLYFLAIIIIGYYSRQRLKSATDYYVAGRQVGAVVNGLALESTYLSPASMLGLPAYIFIL 72 Query: 70 GLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAAI 129 G +WA + G LL LR YA + DY R D +R L + Sbjct: 73 GYPFWWAMSAIIAGMPIATLLTASALRKYA----PTSFADYYADRYNDQR--LRWLVGIV 126 Query: 130 ILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAM 189 ++ Y+ V G+++ II+ YV+ GG A W QA Sbjct: 127 TVIGAVLYITLSLVGMALFLLAVAKVPYIIGLIVGTIIVMLYVVWGGMIATSWNAAFQAF 186 Query: 190 FMLLTLIIMPILALVEIGGLDRATQIIAS---------VDPNKLHPFGGATGWAAIVFAI 240 M + +I + ++++GGL + + + DP H G W A++ Sbjct: 187 LMTVAAVIAAAVIVIKLGGLGGFYEAVLANNPKFWNTPSDPEPPHLLSGT--WIAVIG-- 242 Query: 241 GYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVAS 300 + W G+ P+ V R+ + D + RR IF + I G ++ + Sbjct: 243 WFFVWHYGFATMPYTVVRFFTTMDIKTARR-SIFWCTLAAGIFYMALEIIGAASKLMIET 301 Query: 301 GSIKVE--DPERIVPAMAIHFLPG-----------------WVAGFVIAGIISAVMSTAD 341 G + E + +I+ + + G WV G + AG ++ MSTA Sbjct: 302 GPMGGEGANAVKILQSYMAQYGVGGWTDYSMIAAVEALQNPWVLGILCAGGLAIAMSTAA 361 Query: 342 SQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVAT 401 ++V ++ + RD +L + K++ V ++RI+ +V AI P ++ + Sbjct: 362 GWVMVVNTLLTRDWGDMLLKSKFAKEKPVTLARIISVIFLIVGFLVAINPPGLVLDLSGW 421 Query: 402 AWGGLAVGFGPILTLSLWWKRVTKEA----GIVGMAYGLISEVILEAKIYGWAFNPKAPG 457 A+ + GP L L LWWKR T+ A IV L + + + + AF Sbjct: 422 AFVVIISALGPGLVLGLWWKRATRAAMWTTAIVMTPLHLYAWLKAKLVLGHHAFFFLNDV 481 Query: 458 FFGTLGQWFNGVPVFFINFFVTLFIIIIVSLLTKPPED--VVKLHEELFKKV 507 FG V+ I V + IIVSL+TKP E+ V K EL K+V Sbjct: 482 LFGNAKALITPHQVWAIP--VGFLLFIIVSLITKPVEEEAVQKYCVELTKEV 531 >pir||H71097 hypothetical protein PH1044 - Pyrococcus horikoshii >gi|3257459|dbj|BAA30142.1| (AP000004) 491aa long hypothetical protein [Pyrococcus horikoshii] Length = 491 Score = 134 bits (335), Expect = 2e-30 Identities = 134/506 (26%), Positives = 231/506 (45%), Gaps = 45/506 (8%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 I+ G++ +I+ + K+T + Y V GR + ++ + +S + LG G Sbjct: 19 IVLGWVFLSLIVGVMAGIKRKFTL--EGYLVSGRTLGLIFLYVLMAGEIYSAYAFLGTGG 76 Query: 65 SAFKAGLGAFWAGIGCLFGTLA-DYLLIGPRLRIYAGK-FRAITLPDYLEARLKDNTKLI 122 A+ G+ +A IG +G LA + R AGK F +T DY + R N+K + Sbjct: 77 WAYSYGMPIMYA-IG--YGALAYSFGYFYARYVWKAGKAFGCVTQADYFQVRY--NSKAL 131 Query: 123 RILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVT--TGILITVIILTAYVITGGFFAV 180 +L A I ++F Y+ Q G S+T GI+I +II+ YV T G + Sbjct: 132 AVLVALIGIIFNIPYLQLQLQGLGYIVHVGSLGSITPKAGIVIGMIIMMIYVYTSGLRGI 191 Query: 181 VWTDVVQAMFM-LLTLIIMPILALVEIGGLDRATQIIASVDPNK--LHPFGGATGWAAIV 237 WT+++QA M ++ +++ + + GG+ + +A P+ LHP G + + + + Sbjct: 192 SWTNLLQATLMFIVAWVVLFTIPFKQFGGIGELFKTLAQTKPDHLILHPPLGISWYVSTL 251 Query: 238 FAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFAL 297 G +G+ P + D + L+R + + +I + AGF Sbjct: 252 ILSG-----LGFFMYPQLYPSIYGARDLKTLKRNYVLLP--LYSIFMIPVILAGF----T 300 Query: 298 VASGSIKVEDP-ERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIY 356 VA+ IK+ P E ++ A+ I + P WV G V A +A STA + LL + +++++Y Sbjct: 301 VAALGIKLSAPDEAVLKAVEITY-PSWVLGVVGAAGFAAAASTASAILLSLAGLLSKNLY 359 Query: 357 HKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTL 416 + K++V +SRI V + L+AM A+ P + ++ A+ G+ F P Sbjct: 360 -AIAKPTASDKELVLVSRISVILLGLLAMGLALYSPGRLVSLLLLAYAGMTQMF-PGAVF 417 Query: 417 SLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINF 476 L+WKR+ K A G+ GLI+ L + NP F G W Sbjct: 418 GLFWKRMNKYATGTGIIAGLITVAYLRLVL---KKNPLGIHF----GLW---------GL 461 Query: 477 FVTLFIIIIVSLLTKPPEDVVKLHEE 502 V + + +IV+ LTKP E++ +E Sbjct: 462 LVNIIVTLIVAYLTKPEEELFTRFKE 487 >sp|P32705|YJCG_ECOLI HYPOTHETICAL 59.2 KD PROTEIN IN SOXR-ACS INTERGENIC REGION (F549) >gi|7442761|pir||B65215 hypothetical 59.2 kD protein in soxR-acs intergenic region - Escherichia coli (strain K-12) >gi|396402|gb|AAC43161.1| (U00006) similar to Salmonella proline permease [Escherichia coli] >gi|1790503|gb|AAC77037.1| (AE000480) putative transport protein [Escherichia coli K12] Length = 549 Score = 134 bits (334), Expect = 2e-30 Identities = 113/452 (25%), Positives = 195/452 (43%), Gaps = 19/452 (4%) Query: 2 NFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLG 61 N+ + FLI++V I +WA+K ++ Y+ G + L+ S LG Sbjct: 32 NWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLG 91 Query: 62 YPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKL 121 F +G +G L G LI RLR G++ T D RLK Sbjct: 92 ISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLR-NLGRY---TFADVASYRLKQGP-- 145 Query: 122 IRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVV 181 IRILSA LV + Y+ AQ GK F ++ +++ +++ YV+ GG A Sbjct: 146 IRILSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATT 205 Query: 182 WTDVVQAMFMLLTLIIMPILALVEIG-GLDRATQIIASVDPNKLHPF--GGATGWAAIVF 238 W +++A+ +L M + + +G + +V P + GG Sbjct: 206 WVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISAL 265 Query: 239 AIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALV 298 ++G + G G PHI+ R+ +V D R+ R+ + +G + F GF LV Sbjct: 266 SLG-LGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYIL-TFIIGFGAIMLV 323 Query: 299 ASGSIKVEDPERIVPA--MAIHFLPGWVAGFVIAGIISAV-----MSTADSQLLVASSAI 351 + + ++ MA L V G + G ISAV ++ L +SA+ Sbjct: 324 GANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAV 383 Query: 352 ARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAIT-GPKVIYQMVATAWGGLAVGF 410 + D+Y V + +++ + +S+I V + ++A+ + + I MV A+ A Sbjct: 384 SHDLYANVFKKGATEREELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCN 443 Query: 411 GPILTLSLWWKRVTKEAGIVGMAYGLISEVIL 442 PI+ LS++W ++T ++G GLI+ V+L Sbjct: 444 FPIILLSMYWSKLTTRGAMMGGWLGLITAVVL 475 >pir||E70480 probable sodium/proline symporter ssf [similarity] - Aquifex aeolicus >gi|2984319|gb|AAC07841.1| (AE000773) Na(+):solute symporter (Ssf family) [Aquifex aeolicus] Length = 487 Score = 134 bits (334), Expect = 2e-30 Identities = 128/496 (25%), Positives = 217/496 (42%), Gaps = 76/496 (15%) Query: 63 PGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLI 122 P S +++ L + + G Y+L+ + Y KF T+PD++ R + N + Sbjct: 4 PSSVWRSTLRPRVRRLAYIMGWTGGYVLLALLIAPYLRKFGKFTVPDFIAERYESNFARL 63 Query: 123 RILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVW 182 L AII+ F Y+ Q A G + F V GI I +I++ A + GG ++ W Sbjct: 64 VALIIAIIISF--TYMVGQVAGVGIIMGRLFGVPFEIGIAIGMIVIIATTVLGGMKSITW 121 Query: 183 TDVVQAMFMLLTLIIMPI-LALVEIGGLDRATQIIASV-------------DPNKLHPFG 228 T V Q + +L+T ++P+ L ++ G+ + +V P+ + P+ Sbjct: 122 TQVAQYI-VLITAYLLPVSLLAMQWFGIPLPQFLYGNVLQWIVDLEKQHGISPHYIEPYV 180 Query: 229 --GATGWAAIVFAIGYASWIVGYLGQPHIVTRYM---SVEDPRKLRRPGIFISGIWTTIV 283 + A++F + + G PH++ R+ SV+D R +F I + Sbjct: 181 KFNMIQFLALMFVL-----MAGTAALPHVLMRFFTTPSVKDARWSAGWALFFIAI---LY 232 Query: 284 LWGAFFAGFLGFALVA-------------------SGSIKVEDPE-------------RI 311 L +A F + ++ +G KV D R Sbjct: 233 LTAPAYAAFARYVVLKDVVGKPIDQLPAWAQKWAETGLFKVIDQNGDGIIQWAELQLHRD 292 Query: 312 VPAMAIHFLPGW---VAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQ 368 + +A + G V FV+AG ++A +STAD LLV ++A++ D+Y K++ +K+ Sbjct: 293 IVVLATPEIAGLSLLVGYFVMAGGLAAALSTADGLLLVIAAAVSNDLYAKMINPNAPEKK 352 Query: 369 MVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAG 428 +V + +I VA ++ + A I Q+VA A+ F P L L ++WKR+ KE Sbjct: 353 IVMLGKIAVAVAGVIGGFVAAMKIGFIVQIVAWAFSLATASFFPALVLGIFWKRLNKEGA 412 Query: 429 IVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTLFIIIIVSL 488 I GM GL+ +I + + K G F LG VF V L + IV++ Sbjct: 413 IAGMVAGLLVTII-------YIYLNKTQG-FSILGIQHTASGVF--GLLVNLIVSYIVTM 462 Query: 489 LTKPP-EDVVKLHEEL 503 +T PP E V KL E++ Sbjct: 463 MTPPPSERVQKLVEDI 478 >gb|AAG20007.1| (AE005081) pantothenate permease; PanF [Halobacterium sp. NRC-1] Length = 482 Score = 128 bits (319), Expect = 1e-28 Identities = 121/462 (26%), Positives = 201/462 (43%), Gaps = 44/462 (9%) Query: 13 LVILAYIGWWANKYTKTE-DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGL 71 +V+ +G A + T + + Y++ GR + + A+ S + P A+ G Sbjct: 1 MVVALAVGLVAYRVTDRDAEDYYLAGRGLGTGVLLFTTFATLLSAFTFFAGPNIAYANG- 59 Query: 72 GAFWAGI-----GCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILS 126 W + G LFG L + ++G R + +TL + L R ++ +R L Sbjct: 60 -PEWILVMGLMDGVLFGLL--WYVLGYRQWLLGKANGYVTLGEMLGDRF--GSRGLRGLV 114 Query: 127 AAIILVFMTAYVAAQFAAGGKTFAQAFNVSVT--TGILITVIILTAYVITGGFFAVVWTD 184 A + + ++ YV Q G+ +V G + + YV G V WTD Sbjct: 115 AGVSIFWLFPYVMLQQIGAGEALVGLTGGAVPYWAGAGFITLFMVVYVAISGMRGVAWTD 174 Query: 185 VVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGAT---GWAAIVFAIG 241 +Q +FML + + EI G T +A P + GG W + AIG Sbjct: 175 TLQGVFMLGITWVAFVWVAAEIAG---TTGGLAGALPAEFRALGGGAYSPQWM-LSQAIG 230 Query: 242 YASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVASG 301 A VG P + R+ + R L+R IW +V+ F FL A Sbjct: 231 IA---VGVSMFPQVNQRFFVADSKRTLKRT----FAIWPLLVVL-LFVPAFLMGAWANGV 282 Query: 302 SIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLG 361 + + D E IVP + + PGW A V+AG ++A+MS++DS LL SS RDIY + Sbjct: 283 GLPLPDGENIVPILLSEYTPGWFAALVVAGALAAMMSSSDSMLLSGSSYFTRDIYRPFVN 342 Query: 362 QELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWK 421 + ++ + R+ VAA A+ A ++ P + ++ +TA+GG A P + L+++W+ Sbjct: 343 ADATARREDTLGRVGVAAFAVAAFGGSLLRPGSLLEVGSTAFGGFA-QLAPPVALAMYWR 401 Query: 422 RVTKE---AGIVGMAYGLISEV-----------ILEAKIYGW 449 R TK AG++G ++ V I+ + +GW Sbjct: 402 RTTKAGMFAGVLGTQAFYLATVFGPPVTLAGVPIIASSYFGW 443 >pir||E82043 probable sodium/solute symporter VC2705 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9657301|gb|AAF95845.1| (AE004336) sodium/solute symporter, putative [Vibrio cholerae] Length = 506 Score = 124 bits (309), Expect = 2e-27 Identities = 125/484 (25%), Positives = 197/484 (39%), Gaps = 81/484 (16%) Query: 69 AGLGAF--WAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILS 126 AG+ +F + G L G Y+L+ L Y KF T+PD++ R T + + Sbjct: 2 AGIISFIGYDGTVYLMGWTGGYVLLALCLAPYLRKFGKFTVPDFIGDRYYSRTARMVAVF 61 Query: 127 AAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVV 186 AI + F YVA Q G FA+ V + GI+I + I+ Y + GG + +T V Sbjct: 62 CAIFISF--TYVAGQMRGVGVVFARFLEVDINVGIVIGMAIVFFYAVMGGMKGITYTQVA 119 Query: 187 QAMFMLLTLIIMPILALVEIGGLDRATQI-----IASVDP---NKLHPFGGATGWAAI-- 236 Q ++ ++ I + + G + QI + D NKL G+ A Sbjct: 120 QYCVLIFAFLVPAIFTSLMMTG-NPIPQIGFGSTLTGTDDYLLNKLDGLAVELGFTAYTD 178 Query: 237 -------VFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPG----IFISGIWTTIVLW 285 VF I A+ +VG G PH++ R+ +V R +FI+ ++TT Sbjct: 179 GSKSMVDVFFI-CAALMVGTAGLPHVIIRFFTVPKVSDARVSAGWALVFIAFLYTTAPAV 237 Query: 286 GAFFA-----------------------------------------GFLGFALVASGSIK 304 AF G + ++ A + Sbjct: 238 AAFARVNMIDTINGPDMQGVTAAEAPTWYRNWESTGLVKWEDKNGDGRMFYSGDARNEMT 297 Query: 305 VEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQEL 364 + + ++ + I LP WV + AG ++A +STA LLV S+AI+ D+ K ++ Sbjct: 298 INNDIIVLASPEIAKLPNWVVALLAAGGLAAALSTAAGLLLVISTAISHDLLKKGFKPDM 357 Query: 365 GKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVT 424 KQ + +RI A + A + I P + Q+VA A+G A F P + L +++K++ Sbjct: 358 TDKQELLAARIAAALAIVGAGYLGINPPGFVAQVVAFAFGLAAASFFPAIILGIFYKKMN 417 Query: 425 KEAGIVGMAYGLISEVILEAKIYGWAFNPKA-----------PGFFGTLGQWFNGVPVFF 473 KE I+GM G+ IY NP A P GTLG N V Sbjct: 418 KEGAIIGMLAGITFTAAY--IIYFKFINPAASVPANWWFGISPEGIGTLGMCLNFVVAIV 475 Query: 474 INFF 477 +N F Sbjct: 476 VNKF 479 >pir||S52839 dhlC protein - Xanthobacter autotrophicus >gi|763398|emb|CAA60038.1| (X86084) dhlC [Xanthobacter autotrophicus] Length = 516 Score = 124 bits (308), Expect = 3e-27 Identities = 125/491 (25%), Positives = 208/491 (41%), Gaps = 40/491 (8%) Query: 6 LFGFLIYLVILAY---IGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGY 62 L I++ ILA I WWA + T+T ++ + + + S LG+ Sbjct: 3 LLALAIFVAILALTLAITWWAARRTRTASDFYTADGTLGPIQNGFALAGDWMSAAAFLGF 62 Query: 63 PGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARL-KDNTKL 121 G A G+ G L LA +L+ +R G+F TL D + R+ + +L Sbjct: 63 SGLAALYGMDGSLYAAGALVAFLAILMLVAEPIR-NTGRF---TLGDVIAFRMQRPQARL 118 Query: 122 IRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVV 181 +L ++ + AY+ Q A G V I++ + + YV+ GG A Sbjct: 119 AAVLGTVVVSL---AYLVPQMAGGAALIKLLLGVPYAISIVVVGLGMLVYVVFGGMIATT 175 Query: 182 WTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDP--NKLHPFGGATGWAAIVFA 239 W +++A+ +L ++ L L G D + A+ D K+ G + Sbjct: 176 WVQIIKAVMLLSAAAVLVALLLAHF-GFDPFSVFAAAEDTYGAKILAPGNYLKHPLDQLS 234 Query: 240 IGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFF-----AGFLG 294 +G S+ G G PH++TR+ +V D + RR S +W + L G+FF G Sbjct: 235 LG-LSFAFGTAGLPHVMTRFYTVPDAQTARR-----SAVW-LMFLAGSFFLVTTLIGLGS 287 Query: 295 FALVASGSIKVEDP--ERIVPAMAIHF--LPGWVAGFVIAGIISAV-----MSTADSQLL 345 LV +I+ D +P +A H P + G V ++ AV ++ + L Sbjct: 288 AVLVGQDAIRAADKGGNLALPLLAQHLGGGPDSIGGQVFLAVVVAVAFATILAVVAALTL 347 Query: 346 VASSAIARDIYHKVL-GQELGKKQMVNISRIVVAAVALVAMWFAITGPKV-IYQMVATAW 403 S AIA D+Y VL G + +++ V ++RI V+ A+ F + + + +V A Sbjct: 348 STSGAIAHDLYVNVLRGGHVSEQEQVKVARISTVIVSAFAILFGLLAQGINVAVLVILAI 407 Query: 404 GGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLG 463 A P++ LSL+W+R + GM GL+S V L + G AF A F + Sbjct: 408 SVAASANFPVIVLSLFWQRFNTAGVVTGMVAGLVSAVAL--ALTGPAF-MGADALFPVVN 464 Query: 464 QWFNGVPVFFI 474 VP+ F+ Sbjct: 465 PAIASVPIGFL 475 >sp|P39599|YWCA_BACSU HYPOTHETICAL 55.0 KD PROTEIN IN EPR-GALK INTERGENIC REGION >gi|7442759|pir||S39686 Na+-dependent symport homolog ywcA - Bacillus subtilis >gi|580869|emb|CAA51587.1| (X73124) ipa-31r [Bacillus subtilis] >gi|2636359|emb|CAB15850.1| (Z99123) alternate gene name: ipa-31r~similar to Na+-dependent symport [Bacillus subtilis] Length = 516 Score = 122 bits (302), Expect = 1e-26 Identities = 108/435 (24%), Positives = 195/435 (44%), Gaps = 19/435 (4%) Query: 17 AYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWA 76 AY + K TKT +++ G + + L+ S LG G G F+ Sbjct: 20 AYYHVFCAKRTKTTSEFYTAGGGLTGVQNGLAIAGDYMSAASFLGIAGMIALYGFDGFFY 79 Query: 77 GIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTA 136 IG L L ++ LR GK+ T+ D + AR K+ K IR ++A + T Sbjct: 80 SIGFLVAYLVVLYIVAEPLR-NLGKY---TMADMIAARFKE--KKIRGVAALNTIAISTF 133 Query: 137 YVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLI 196 Y+ AQ G + T +LI +++T YV+ GG A W +++A+ ++ + Sbjct: 134 YMIAQLVGAGALIKLLLGLDYTAAVLIVGVLMTIYVVFGGMIATSWVQIIKAVLLMAGTL 193 Query: 197 IMPILALVEIG-GLDRATQIIASVDP---NKLHPFGGATGWAAIVFAIGYASWIVGYLGQ 252 ++ I+ + G L+ + + + P + L+P G ++ A ++G G Sbjct: 194 VISIIVFSKFGFSLNTMFEQMKTATPLGADFLNP-GNKYKVPLETLSLNLA-LVLGTAGL 251 Query: 253 PHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLW-GAFFAGFLGFALVASGSIKVEDP--E 309 PHI+ R+ +V+D + R +S W V + F GF A V +I D Sbjct: 252 PHILIRFYTVKDAKTARTS--VVSATWIIGVFYIMTVFLGFGAAAFVGFDAITAADQAGN 309 Query: 310 RIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQ-ELGKKQ 368 P +A ++ FV A + +++ +L A+SA A DIY +++ + E +K+ Sbjct: 310 MAAPLLAKALGGDFLFAFVSAIAFATILAVVTGLVLSAASAFAHDIYSQIIRKGEATEKE 369 Query: 369 MVNISRIVVAAVALVAMWFAITGPKV-IYQMVATAWGGLAVGFGPILTLSLWWKRVTKEA 427 + +R AV+++++ AI + + +VA A+ A P++ +++WKR Sbjct: 370 QMKAARWASVAVSVLSILLAIFAQSLNVAFLVALAFAVAASANLPLIVFTVFWKRFNASG 429 Query: 428 GIVGMAYGLISEVIL 442 + G GLIS ++L Sbjct: 430 ALWGSLTGLISALVL 444 >gi|11497853 pantothenate permease (panF-3) [Archaeoglobus fulgidus] >gi|7442769|pir||E69279 pantothenate permease (panF-3) homolog - Archaeoglobus fulgidus >gi|2650404|gb|AAB90996.1| (AE001089) pantothenate permease (panF-3) [Archaeoglobus fulgidus] Length = 461 Score = 118 bits (294), Expect = 1e-25 Identities = 114/450 (25%), Positives = 197/450 (43%), Gaps = 43/450 (9%) Query: 6 LFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65 L+ F+ Y++I I A K +T+++Y++ GRKV + + L+ A+ +S ++M+G G Sbjct: 8 LYAFIGYIIIGTAIAIMAMKGLRTQEEYYIAGRKVSGVISALTYAATTYSAFMMVGLVGL 67 Query: 66 AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRIL 125 ++ +G+GA + L GTL PR+ A + +T D + R + L Sbjct: 68 SYFSGVGALGFELFYLVGTLFLLSYYAPRVWEMAKERGYVTPGDMIAERYGSE---VAKL 124 Query: 126 SAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDV 185 A I+ + + Y++ Q ++ +S GI+ + I++ + GG V WTD Sbjct: 125 MAVIVSIALIPYISVQLIGVSLILSKTNAMSFEAGIVASAILIALWAFLGGLRGVAWTDA 184 Query: 186 VQAMFMLLTLIIMPILALVEIGGLDRATQIIAS------VDPNKLHPFGGATGWAAIVFA 239 +Q +FMLL + I IL + + G ++ S V PN + W + F Sbjct: 185 LQGVFMLL-MAIAAILWVHQYGFAEKDFFTEVSRLGELLVVPNSI--------WTPVKFI 235 Query: 240 IGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGI---FISGIWTTIVLWGAFFAGFLGFA 296 W L P + R +D LRR I F I+T IV +G Sbjct: 236 SLTLPWFFFALTNPQVFQRLYIPKDRSALRRMVILFGFFGLIYTVIVT-------LIGLE 288 Query: 297 LVASGSI----KVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIA 352 L + KV D + + P M + +P + + I +A ++TA+S +L SS I Sbjct: 289 LRTMTEMGVFPKVPDRDAVTPTM-LAMMPPLLGAAISLSIFAAAITTANSIVLTLSSMIT 347 Query: 353 RDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGP 412 RD+ LG E V R+++ + + FA + P I ++ + L P Sbjct: 348 RDL----LGSE-----KVGSGRVLIVILTVAVALFAYSRPGYIVELSVLSSTILLCQL-P 397 Query: 413 ILTLSLWWKRVTKEAGIVGMAYGLISEVIL 442 ++ R + AGI ++ G I+ V+L Sbjct: 398 LILGVFHLNRGGRLAGIATLSAGFITAVVL 427 >pir||C82582 Na+-dependent symport homolog XF2251 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9107405|gb|AAF85050.1|AE004037_11 (AE004037) solute:Na+ symporter [Xylella fastidiosa] Length = 577 Score = 116 bits (289), Expect = 5e-25 Identities = 108/471 (22%), Positives = 200/471 (41%), Gaps = 35/471 (7%) Query: 1 MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60 +N+ ++ F+++++I +I WA K T++ ++ G + L+ S L Sbjct: 34 VNWVVISIFVVFVLITLWITKWAAKRTRSSADFYTAGGTITGFQNGLAMAGDYMSAAAFL 93 Query: 61 GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTK 120 G + +G IG L G L+ RLR GK+ + Y A + Sbjct: 94 GITSAVMISGYDGMLYAIGSLVGWPILVFLVAERLR-NLGKYTFADVVAYRFAAVP---- 148 Query: 121 LIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAV 180 +R+ ++A LV + + AQ G F + +++ ++ YV+ GG A Sbjct: 149 -VRLFTSASTLVVVLCSLVAQMVGAGALIKLLFGLDYWVAVILVGGLMMVYVMFGGMAAT 207 Query: 181 VWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAI 240 W +++A+ +L L M ++ + G A ++ GG +G A + Sbjct: 208 TWVQIIKAVLLLTCLTFMAVMIMWRFGFNFEGLFASAVGVKTQIAMAGGKSGEEAKALGL 267 Query: 241 GY-----------------ASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIF-ISGIWTTI 282 + + G +G PHI+ R+ +V D R++R ++ I+ I Sbjct: 268 SIMAPGSFIKDPISAISLGIALVFGNVGLPHILMRFFAVPDAREVRHSVLWAITWIGYCY 327 Query: 283 VLWGAFFAGFLGFAL-------VASGSIKVEDPERIVPAMAIHFLPGW--VAGFVIAGII 333 +L G + F L +A+G+I+ + A+ + + G GFV A Sbjct: 328 ILMFIVGFGAIVFVLTNPQYADIATGTIRGGQGAANMAAVLVAKVVGGDVFMGFVSAVAF 387 Query: 334 SAVMSTADSQLLVASSAIARDIYHKVLGQ-ELGKKQMVNISRIVVAAVALVAMWFAITGP 392 + +++ A L +SA++ D+Y V+ Q + + +SR+ A + +VA+ I Sbjct: 388 ATILAVAAGLALSGASAVSHDVYAMVIKQGKPSSDTELLVSRVTTAVLGVVAVLLGIVFQ 447 Query: 393 KV-IYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVIL 442 K + MV+ A+ A P+L LSL WK T ++G GLIS ++L Sbjct: 448 KQNVAFMVSLAFAIAASANFPVLILSLLWKNCTTWGAVIGGFLGLISSLVL 498 >emb|CAA94864.1| (Z71176) phenylacetic acid permease [Pseudomonas putida] >gi|3253206|gb|AAC24338.1| (AF029714) PhaJ [Pseudomonas putida] Length = 520 Score = 113 bits (281), Expect = 4e-24 Identities = 111/459 (24%), Positives = 190/459 (41%), Gaps = 30/459 (6%) Query: 1 MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60 MN+ + F++++ + WA T++ ++ G + + L+ S L Sbjct: 1 MNWTAISMFMVFVCFTLLVTRWAALRTRSASDFYTAGGGLTGMQNGLAIAGDMISAASFL 60 Query: 61 GYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTK 120 G F G +G L G LI RLR GK+ T D + RL Sbjct: 61 GISAMMFMNGYDGLLYALGVLAGWPIILFLIAERLR-NLGKY---TFADVVSYRLAQTP- 115 Query: 121 LIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAV 180 +R+ SA LV Y+ AQ GK F +S +++ +++ AYV GG A Sbjct: 116 -VRLTSAFGTLVVALMYLVAQMVGAGKLIELLFGISYLYAVMLVGVLMVAYVTFGGMLAT 174 Query: 181 VWTDVVQAMFMLLTLIIMPILALVEIGGLDR---ATQIIASVDPNKLHPFGGATGWAAIV 237 W +++A+ +L M + L G A+ + + GG Sbjct: 175 TWVQIIKAVMLLSGTSFMAFMVLKHFGFSTEAMFASAVAVHAKGQAIMAPGGLLSNPVDA 234 Query: 238 FAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFAL 297 ++G + G G PHI+ R+ +V D ++ R+ + +G L GF + Sbjct: 235 ISLG-LGMMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYLL-LIVIGFGAIVM 292 Query: 298 VASGSIKVEDPERIVPA---MAIHFLPGWVAGFVIAGIISAV-----MSTADSQLLVASS 349 V + + I+ +A+H L V G + G ISAV ++ L +S Sbjct: 293 VGTEPSYRDATGAIIGGGNMIAVH-LAQAVGGNLFLGFISAVAFATILAVVAGLALSGAS 351 Query: 350 AIARDIYHKVLGQ-ELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWG---- 404 A++ D+Y V+ Q + +++ + +SRI + L+A+ + G Q +A G Sbjct: 352 AVSHDLYACVIRQGKATEQEEMRVSRIATLLIGLLAV---LLGLMFESQNIAFLSGLVLA 408 Query: 405 -GLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVIL 442 +V F P+L LS++WK +T + G GL S V+L Sbjct: 409 VAASVNF-PVLLLSMFWKGLTTRGAVCGSMAGLASAVLL 446 >sp|P96169|SGLT_VIBPA SODIUM/GLUCOSE COTRANSPORTER (NA(+)/GLUCOSE SYMPORTER) >gi|8886895|gb|AAF80602.1|AF255301_1 (AF255301) Na+/galactose cotransporter SGLT [Vibrio parahaemolyticus] Length = 543 Score = 109 bits (270), Expect = 8e-23 Identities = 107/471 (22%), Positives = 194/471 (40%), Gaps = 57/471 (12%) Query: 1 MNFGILFGFLIYLVILAYIGWWANKYTK-----TEDQYFVGGRKVHVLAATLSDKASDFS 55 ++F + F IY+ I+ +G W ++ K TED YF+ G+ + A S A++ S Sbjct: 8 LSFIDIMVFAIYVAIIIGVGLWVSRDKKGTQKSTED-YFLAGKSLPWWAVGASLIAANIS 66 Query: 56 GWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKF--------RAITL 107 +G GS + GL +A Y + I GK+ T+ Sbjct: 67 AEQFIGMSGSGYSIGLA------------IASYEWMSAITLIIVGKYFLPIFIEKGIYTI 114 Query: 108 PDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVII 167 P+++E R N KL IL+ I +++ + + GG + + IL + Sbjct: 115 PEFVEKRF--NKKLKTILAVFWISLYIFVNLTSVLYLGGLALETILGIPLMYSILGLALF 172 Query: 168 LTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDR-ATQIIASVDPNKLH- 225 Y I GG AVVWTDV+Q F++L + +A+ IGG D + VD H Sbjct: 173 ALVYSIYGGLSAVVWTDVIQVFFLVLGGFMTTYMAVSFIGGTDGWFAGVSKMVDAAPGHF 232 Query: 226 ---------PFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFIS 276 + G A ++ + A+ Q +I+ R ++ + + ++ GI + Sbjct: 233 EMILDQSNPQYMNLPGIAVLIGGLWVANLYYWGFNQ-YIIQRTLAAKSVSEAQK-GIVFA 290 Query: 277 GIWTTIVLWGAFFAGFLGFALVASGSI-------------KVEDPERIVPAMAIHFLPGW 323 IV + G + + + + + ++ P + FLP Sbjct: 291 AFLKLIVPFLVVLPGIAAYVITSDPQLMASLGDIAATNLPSAANADKAYPWLT-QFLPVG 349 Query: 324 VAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALV 383 V G V A + +A++S+ S L ++ DIY + + + G ++VN+ R ++ Sbjct: 350 VKGVVFAALAAAIVSSLASMLNSTATIFTMDIYKEYISPDSGDHKLVNVGRTAAVVALII 409 Query: 384 AMWFA--ITGPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGM 432 A A + G +Q + G ++ G + L L+WK+ T + I+G+ Sbjct: 410 ACLIAPMLGGIGQAFQYIQEYTGLVSPGILAVFLLGLFWKKTTSKGAIIGV 460 >dbj|BAA11215.1| (D78137) Na+/glucose symporter [Vibrio parahaemolyticus] Length = 530 Score = 109 bits (269), Expect = 1e-22 Identities = 106/463 (22%), Positives = 190/463 (40%), Gaps = 57/463 (12%) Query: 9 FLIYLVILAYIGWWANKYTK-----TEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYP 63 F IY+ I+ +G W ++ K TED YF+ G+ + A S A++ S +G Sbjct: 3 FAIYVAIIIGVGLWVSRDKKGTQKSTED-YFLAGKSLPWWAVGASLIAANISAEQFIGMS 61 Query: 64 GSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKF--------RAITLPDYLEARL 115 GS + GL +A Y + I GK+ T+P+++E R Sbjct: 62 GSGYSIGLA------------IASYEWMSAITLIIVGKYFLPIFIEKGIYTIPEFVEKRF 109 Query: 116 KDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITG 175 N KL IL+ I +++ + + GG + + IL + Y I G Sbjct: 110 --NKKLKTILAVFWISLYIFVNLTSVLYLGGLALETILGIPLMYSILGLALFALVYSIYG 167 Query: 176 GFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDR-ATQIIASVDPNKLH--------- 225 G AVVWTDV+Q F++L + +A+ IGG D + VD H Sbjct: 168 GLSAVVWTDVIQVFFLVLGGFMTTYMAVSFIGGTDGWFAGVSKMVDAAPGHFEMILDQSN 227 Query: 226 -PFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVL 284 + G A ++ + A+ Q +I+ R ++ + + ++ GI + IV Sbjct: 228 PQYMNLPGIAVLIGGLWVANLYYWGFNQ-YIIQRTLAAKSVSEAQK-GIVFAAFLKLIVP 285 Query: 285 WGAFFAGFLGFALVASGSI-------------KVEDPERIVPAMAIHFLPGWVAGFVIAG 331 + G + + + + + ++ P + FLP V G V A Sbjct: 286 FLVVLPGIAAYVITSDPQLMASLGDIAATNLPSAANADKAYPWLT-QFLPVGVKGVVFAA 344 Query: 332 IISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFA--I 389 + +A++S+ S L ++ DIY + + + G ++VN+ R ++A A + Sbjct: 345 LAAAIVSSLASMLNSTATIFTMDIYKEYISPDSGDHKLVNVGRTAAVVALIIACLIAPML 404 Query: 390 TGPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGM 432 G +Q + G ++ G + L L+WK+ T + I+G+ Sbjct: 405 GGIGQAFQYIQEYTGLVSPGILAVFLLGLFWKKTTSKGAIIGV 447 >pir||S75887 hypothetical protein - Synechocystis sp. (strain PCC 6803) >gi|1653432|dbj|BAA18346.1| (D90913) sodium-coupled permease [Synechocystis sp.] Length = 512 Score = 108 bits (268), Expect = 1e-22 Identities = 117/460 (25%), Positives = 197/460 (42%), Gaps = 33/460 (7%) Query: 10 LIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKA 69 L+Y I+ IG A++ D+YF G +++ A S A+ FS +LG PG + Sbjct: 10 LVYSAIVIAIGAIASRKQDNTDEYFRGAKQIPWWALGFSIIATSFSAASLLGGPGEGYGH 69 Query: 70 GLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAAI 129 G +G L G Y L+ + + T +YLE R T R L + Sbjct: 70 GFLYLQLQLGDLIG----YGLVIAVFLPFFVRLNLTTAYEYLERRFDAKT---RSLGSLC 122 Query: 130 ILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQ-- 187 L+F+ A + A + +S T IL+ ++ Y + GG AVVWTDV+Q Sbjct: 123 FLLFVIARLGGLLYAAALVLSVLTGISTNTAILMVGVVSIIYTVAGGITAVVWTDVLQFG 182 Query: 188 AMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAI------VFAIG 241 +F+ L I + V GG +I + KL F A+I + A G Sbjct: 183 MIFVGLGAGIWAAVTAVP-GGFGELWRIAG--ENGKLVVFNFDWDPASIRSLPTALIAYG 239 Query: 242 YASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFIS------GIWTTIVLWGAFFAGFLGF 295 ++ V Q V RY+S D + R+ IF+ G+ T++L G F Sbjct: 240 ILAFAVAGTNQ-QSVQRYVSCADEQSARK-AIFLGWFSGVLGVGATLLL-GVLLFSFYQL 296 Query: 296 ALVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 G+IK P+ I+ ++ +P +GF++A I +A MS+ DS L ++ + D Sbjct: 297 QGGLPGNIK---PDEILSYFIVNQVPPGASGFLVAAIFAAAMSSIDSALHSLATCMTVDF 353 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 Y + + + + + V +++ ++ +VA++ AI ++ + GP+L Sbjct: 354 YDRYINIQASEMRSVRVAQGLIIVWGVVAIFSAIYAASTGQDLLEFLVSYTTMFLGPLLG 413 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILE--AKIYGWAFNP 453 + L + +G YG ++ V+L A GW P Sbjct: 414 IFLMGV-LFPRINALGAFYGTVAAVLLVIIASNAGWLTFP 452 >pir||E83468 probable sodium:solute symport protein PA1418 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9947366|gb|AAG04807.1|AE004571_6 (AE004571) probable sodium:solute symport protein [Pseudomonas aeruginosa] Length = 463 Score = 106 bits (263), Expect = 5e-22 Identities = 121/454 (26%), Positives = 192/454 (41%), Gaps = 46/454 (10%) Query: 6 LFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVH------VLAATLSDKASDFSGWLM 59 +F LIY + +GW+ + KT D Y V GR + +AAT+ AS G + Sbjct: 5 IFVVLIYAAGMIALGWYGMRRAKTRDDYLVAGRNLGPGFYLGTMAATVLGGASTI-GTVR 63 Query: 60 LGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNT 119 LGY G+ FW G + L + L K + T+ LE R Sbjct: 64 LGYVH-----GISGFWLCGAIGLGIVGLSLFLAKPLL----KLKIYTVTQVLERRYNPAA 114 Query: 120 KLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFA 179 R SA I+LV+ A A G F + ILI ++ Y GG ++ Sbjct: 115 ---RHASALIMLVYALMIGATSTIAIGTVMQVLFGLPFWVSILIGGGVVVLYSTIGGMWS 171 Query: 180 VVWTDVVQAMFMLLTLI--IMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIV 237 + TD+VQ + M + L+ +MP L++ + GG D ++A + P F A GW IV Sbjct: 172 LTLTDIVQFLIMTVGLVFLLMP-LSINDAGGWDA---LVAKL-PASYFDFT-AIGWDTIV 225 Query: 238 --FAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGF 295 F I + +G I R + + G +GI+ + G G Sbjct: 226 TYFLIYFFGIFIGQ----DIWQRVFTARSETVAKVAGS-AAGIYCVLY-------GMAGA 273 Query: 296 ALVASGSIKVEDPERIVPAMAI---HFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIA 352 + + + + D E + A A H LP + G VIA ++A+MSTA + LL AS+ + Sbjct: 274 LIGMAAKVLLPDLENVNNAFASVVEHSLPNGIRGLVIAAALAALMSTASAGLLAASTTVT 333 Query: 353 RDIYHKV-LGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFG 411 +D+ ++ G+ V+ +RI + LV + A+ VI + A+ L G Sbjct: 334 QDLLPRLRRGRGQSDNGDVHENRIATLLLGLVVLGIALVVSDVI-SALTVAYNLLVGGML 392 Query: 412 PILTLSLWWKRVTKEAGIVGMAYGLISEVILEAK 445 L +++WKR T I M G ++ ++ K Sbjct: 393 IPLIGAIYWKRATTAGAITSMTLGFLTVLVFMIK 426 >pir||B69833 metabolite permease homolog yhjB - Bacillus subtilis >gi|2226174|emb|CAA74464.1| (Y14081) hypothetical protein [Bacillus subtilis] >gi|2633381|emb|CAB12885.1| (Z99109) similar to metabolite permease [Bacillus subtilis] Length = 489 Score = 105 bits (260), Expect = 1e-21 Identities = 111/498 (22%), Positives = 215/498 (42%), Gaps = 37/498 (7%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTE-DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYP 63 I+FG L+ + ++G A K +Q+ VGGR + L ++ + LG Sbjct: 7 IIFGVLLLSI---FLGIRAQKGKDMNLEQWTVGGRGFGTVFVFLLMAGEIYTTFTFLGGS 63 Query: 64 GSAFKAGLGAFWA-GIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLI 122 G A+ G AF+ GCL L+ +LL P + YA + + ++ D+ K N+ L+ Sbjct: 64 GWAYGKGGPAFYIIAYGCLAYILSYWLL--PAVWTYAKQHKLMSQSDFFTK--KYNSPLL 119 Query: 123 RILSAAIILVFMTAYVAAQFAAGGKTFAQAF--NVSVTTGILITVIILTAYVITGGFFAV 180 IL + + + + Y+ Q G ++ ++ T I I + +T YV+ G Sbjct: 120 GILVSLVGIAALIPYLVLQLKGLGLIVSETSYGKITPTAAIWIGAVSITVYVMVSGIHGS 179 Query: 181 VWTDVVQAMFMLLTLIIMPI-LALVEIGGLDRATQIIASVDPN--KLHPFGGATGW---A 234 W VV+ + +L+ ++ + + L + GG Q I + P L G + W Sbjct: 180 AWISVVKDIMILVVVLFLGVYLPIHYYGGFQDMFQQIETAKPGFLTLPESGQSVAWFSST 239 Query: 235 AIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLG 294 ++ A+G+ W PH + S E+P+ R+ I I ++ ++L F F+G Sbjct: 240 VLLTALGFYMW-------PHTFSASYSAENPKVFRKNAI-IMPLYQLVLL----FVLFVG 287 Query: 295 FALVAS-GSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIAR 353 FA + + D + + +++ W G + A + + L+ AS+ A+ Sbjct: 288 FAAILQVPDLNGADGDLSLLRLSLQAFDPWFVGIIGAAGLLTALVPGSMILMSASTLFAK 347 Query: 354 DIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPI 413 ++Y KV+ ++Q+ +++ +V +AL++++F G I ++ + + F + Sbjct: 348 NVY-KVIAPRTTEQQVSALAKFLVPVIALISVYFTFKGGNTIVTLLLMGYSLVTQLFPAL 406 Query: 414 LTLSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFF 473 L L VTK+ G+ G + A Y F L Q + V Sbjct: 407 LFSLLKHNMVTKQGAFAGIIAG------VGAVTYITMTETTIGTLFPALPQAAKDLNVGI 460 Query: 474 INFFVTLFIIIIVSLLTK 491 + + + +++ VSL+T+ Sbjct: 461 VALLLNITVMMAVSLMTR 478 >pir||H75513 probable sodium/proline symporter DR0477 [similarity] - Deinococcus radiodurans (strain R1) >gi|6458165|gb|AAF10057.1|AE001907_3 (AE001907) sodium:solute symporter protein [Deinococcus radiodurans] Length = 528 Score = 105 bits (260), Expect = 1e-21 Identities = 105/458 (22%), Positives = 188/458 (40%), Gaps = 33/458 (7%) Query: 6 LFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65 L LI L+ L W +++ T D Y GG K+ ++ S LG G Sbjct: 4 LLAALIVLITLGVTFWASSRNTSAGDFYVAGG-KISATQNGIAIAGDYMSAASFLGITGL 62 Query: 66 AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRIL 125 G F +G L ++ LR GK+ TL D L RLKD +R Sbjct: 63 IALNGYDGFMYSVGWFIAYLTVLFIVAEPLR-NLGKY---TLADMLVYRLKDQR--VRFY 116 Query: 126 SAAIILVFMTAYVAAQFAAGGKTFAQAFN--VSVTTGILITVIILTAYVITGGFFAVVWT 183 +A + T Y+ AQ G + + T I + +++ YV+ GG A W Sbjct: 117 AAFSTITVSTFYMIAQVVGAGSLISLLSGGLLKPTLAIPLVGLLMIVYVVVGGMLATTWV 176 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNK---LHP---FGGATGWAAIV 237 +++AM ++ I+M +L L G + + A+ D N L P + ++ Sbjct: 177 QIIKAMLLMFATIVMSVLILARF-GFSFSDLLGAATDKNGAAFLEPGLKYKNPLDLISLC 235 Query: 238 FAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFAL 297 A+ ++G G PHI+ R+ +V + R+ + G+ + A G L Sbjct: 236 LAL-----VLGTAGLPHILVRFFTVPTAQDARKSVVVAMGLIGAFYIMTALM-GNAANVL 289 Query: 298 VASGSIKVEDPERIVPAMAIHFLPGWVAG---------FVIAGIISAVMSTADSQLLVAS 348 V +I +P + A + G AG FV A + +++ + AS Sbjct: 290 VGKDTIVAANPAGNMAAPLLAQALGGGAGTLGGEFGLAFVTAVAFATILAVVAGLTISAS 349 Query: 349 SAIARDIYHKVL-GQELGKKQMVNISRIVVAAVALVAMWFAITG-PKVIYQMVATAWGGL 406 ++ DIY+ V+ G + +++ ++R+ AV L+++ + + + +VA A+ Sbjct: 350 TSFTHDIYNGVMKGGKANEQEQFKVARMATVAVGLLSIVLGLLAKDQNVAFLVALAFAIA 409 Query: 407 AVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVILEA 444 A P++ +L+W+ + G+ GL ++L A Sbjct: 410 ASANLPVILYTLFWRGFNANGAVWGIVGGLAVTLVLIA 447 >gb|AAF54633.1| (AE003691) CG6723 gene product [Drosophila melanogaster] Length = 587 Score = 105 bits (259), Expect = 2e-21 Identities = 120/458 (26%), Positives = 193/458 (41%), Gaps = 55/458 (12%) Query: 9 FLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFK 68 FL+ + I Y G+ NK + +ED Y +GGRK+ V+ S AS SG +LG P + Sbjct: 26 FLLCIGIGIYFGFM-NK-SVSEDDYMLGGRKMLVIPIAFSLVASFVSGITLLGLPTEVYS 83 Query: 69 AGLGAFWA-----GIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIR 123 G+ + G+G + G YL + L I + +YLE R + +R Sbjct: 84 YGIQYLYVSCGVIGMGVVMGVF--YLPVFHDLNI-------TSTYEYLEVRFD---RRLR 131 Query: 124 ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 + + + + AY+ F Q + V T I II Y GG AVVWT Sbjct: 132 LYGSVMFAIMNVAYLPIVIYVPALAFNQVTGIGVHTITPIVCIICVFYTSLGGLKAVVWT 191 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGL----------DRATQIIASVDPNKLHPFGGATGW 233 DVVQA+ ML L ++ I +IGG DR S+DP H F W Sbjct: 192 DVVQAISMLGALCLVAIKGTRDIGGAGVVLERAWSSDRLEAPDLSIDPTVRHTF-----W 246 Query: 234 AAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRP-GIFISGIWTTIVLWG----AF 288 +F G W +++ RY+S+ R+ IF G+ + L G Sbjct: 247 C--LFFGGIVYWTQTNAVSQNMIQRYLSLPSLGDARKALCIFCVGVLILMALCGYNGLLI 304 Query: 289 FAGFLGFALVASGSIKVEDPERIVPAMAIHF---LPGWVAGFVIAGIISAVMSTADSQLL 345 +A + + + K D +++P + LPG + G IAG+ SA +S+ + L Sbjct: 305 YATYQNCDPLTTKLAKARD--QLLPLFVMKTLGELPG-MTGLFIAGVFSAALSSLSTCLN 361 Query: 346 VASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVAL--VAMWFAITGPKVIYQMVATAW 403 S+ + D + + L + I R+VV V + V + + + + Q+ + Sbjct: 362 SMSAVVLEDFVKPYVKKPLSSSAINWIMRLVVVGVGVLCVCLVYVVEHMGTVLQLTMSL- 420 Query: 404 GGLAVGFGP---ILTLSLWWKRVTKEAGIVGMAYGLIS 438 A+ GP I T+ L+ + + +VG G+I+ Sbjct: 421 --EAITNGPLFGIFTIGLFLPWINGNSALVGGVMGVIA 456 >emb|CAB59438.1| (AL132644) putative transmembrane transport protein [Streptomyces coelicolor A3(2)] Length = 544 Score = 104 bits (258), Expect = 2e-21 Identities = 112/458 (24%), Positives = 194/458 (41%), Gaps = 39/458 (8%) Query: 9 FLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFK 68 F ++++ I WA + TK ++ GGR+ L+ S LG G+ Sbjct: 28 FAVFVLATLGITVWAGRQTKDAADFYAGGRQFSAFQNGLAVSGDYMSAASFLGIAGAIAL 87 Query: 69 AGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAA 128 G F IG L L LL+ LR +G++ T+ D L R++ + +R + Sbjct: 88 FGYDGFLYSIGFLVAWLVALLLVAEPLR-NSGRY---TMGDVLAYRMRQ--RPVRTAAGT 141 Query: 129 IILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITV----IILTAYVITGGFFAVVWTD 184 +V Y+ AQ A G + ++ G ++ V +++ YV GG W Sbjct: 142 STIVVSIFYLLAQMAGAGILVSLLLGITSDAGKILIVALVGVLMIVYVTIGGMKGTTWVQ 201 Query: 185 VVQAMFMLLTLIIMPILALVEIG---------GLDRATQIIASVDPNKLHPFGGATGWAA 235 +V+A+ ++ I++ L L++ + + A ++P + GA+G Sbjct: 202 MVKAVLLIGGTILITFLVLLKFDFNISDLLGKAAENSGAGSAFLEPGLQY---GASGTTK 258 Query: 236 IVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGF 295 + F + ++G G PHI+ R+ +V + + R+ + GI L GF Sbjct: 259 LDFISLGIALVLGTAGLPHILIRFYTVPNAKAARKSVNWAIGIIGAFYLM-TIALGFGAA 317 Query: 296 ALVASGSIKVEDP--ERIVPAMAIHFLPGWVA---GFVIAGIISAV-----MSTADSQLL 345 ALV I +P P +A+H G V G ++ ISAV ++ L Sbjct: 318 ALVGKDEIIASNPSGNTAAPLLALHV--GGVDSTWGAILLATISAVAFATILAVVAGLTL 375 Query: 346 VASSAIARDIYHKVL--GQELGKKQMVNISRIVVAAVALVAMWF-AITGPKVIYQMVATA 402 +SS+ A DIY V+ GQ K++M +R + +V++ A+ + +VA A Sbjct: 376 ASSSSFAHDIYANVIRKGQATEKEEM-RAARWATVFIGIVSIALGALARDLNVAGLVALA 434 Query: 403 WGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEV 440 + A P + SL+WKR T + + + GLI V Sbjct: 435 FAVAASANLPTILYSLFWKRFTTQGALWSIYGGLIVAV 472 >pir||T03475 transmembrane protein - Rhodobacter capsulatus >gi|3128276|gb|AAC16128.1| (AF010496) transmembrane protein DhlC homolog [Rhodobacter capsulatus] Length = 578 Score = 104 bits (257), Expect = 3e-21 Identities = 109/467 (23%), Positives = 187/467 (39%), Gaps = 39/467 (8%) Query: 6 LFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65 +FGF ++V +I WA TK+ ++ G + L+ S LG + Sbjct: 45 MFGF--FVVATLFITKWAAGRTKSAADFYTAGGGITGFQNGLAIAGDYMSAASFLGISAA 102 Query: 66 AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRIL 125 G IG L G L+ RLR GKF + + A+ +R+ Sbjct: 103 VMLQGYDGLIYSIGFLVGWPILTFLMAERLR-NLGKFTFADVAAFPFAQTP-----VRVF 156 Query: 126 SAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDV 185 +A LV + Y+ AQ G+ F + +++ I++ YV+ GG A W + Sbjct: 157 AAMSTLVVVAFYLIAQMVGAGQLIKLLFGLEYLYAVIVVGILMMVYVLFGGMTATTWVQI 216 Query: 186 VQAMFMLLTLIIMPILALVEIG-----------GLDRATQIIASVDPNK-----LHPFGG 229 ++A +L M ++ +V G + + A P + + G Sbjct: 217 IKACLLLGGASFMALMVMVHYGFSLESLFADSVKVKTDLALAAGKTPEEAAAAGISIMGP 276 Query: 230 ATGWAAIVFAIGYASWIV-GYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAF 288 T + AI + ++ G G PHI+ R+ +V ++ R+ + + +W F Sbjct: 277 GTFVKDPISAISFGMALMFGTAGLPHILMRFFTVPSAKEARK-SVMWATVWIGYFYMLTF 335 Query: 289 FAGF--LGFALVASGSIKVEDPERIVPA----MAIHFLPGWVAGFVIAGIISAV-----M 337 GF + + L G + + + MA L V G + G ISAV + Sbjct: 336 IIGFGAIVYVLTNPGLVSYDAKGALTLVGGNNMAAIHLAQAVGGNIFLGFISAVAFATIL 395 Query: 338 STADSQLLVASSAIARDIYHKVLGQ-ELGKKQMVNISRIVVAAVALVAMWFAITGPKV-I 395 + L +SA++ D+Y V + + +SRI + +VA+ + K I Sbjct: 396 AVVAGLTLSGASAVSHDLYSTVFKNGKADSASELRVSRITTICLGIVAVVLGLAFEKQNI 455 Query: 396 YQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVIL 442 MV+ A+ A P+L +SL WK +T ++G + GLIS V L Sbjct: 456 AFMVSLAFAIAASANFPVLFMSLLWKGMTTRGAVIGGSLGLISSVAL 502 >dbj|BAB05941.1| (AP001514) Na+/myo-inositol cotransporter [Bacillus halodurans] Length = 580 Score = 101 bits (249), Expect = 2e-20 Identities = 90/409 (22%), Positives = 184/409 (44%), Gaps = 31/409 (7%) Query: 5 ILFGFLIYLVILAYIGWWANKYT--KTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGY 62 IL FL+Y + + + W+ + T + D YF+GGR + + S ++ S ++G Sbjct: 5 ILASFLMYSIFVMWFSWYKTRGTDLSSSDGYFLGGRSLTGIVIASSLILTNLSTEQVVGL 64 Query: 63 PGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLI 122 G AF + + + + PR K T+PD+LE R T+ Sbjct: 65 NGQAFGESMVVMAWEVTAPIALILMAFVFLPRYL----KLGITTIPDFLEQRFDLRTR-- 118 Query: 123 RILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILT----------AYV 172 +I+S +L + T ++ +G F++S I +I+L YV Sbjct: 119 QIVSVLFLLGYATVFLPTVLYSGALVIDSIFSLSSVMDISPFMIVLCISIAIGIISCGYV 178 Query: 173 ITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQI--IASVDPNKLHPFGG- 229 I GG A +D + + +++ +++PILAL +G D A+ + + S +P KL+ G Sbjct: 179 ILGGLKACAMSDTINGIGLIIGGLLIPILALFVLGRGDFASGVGELVSANPTKLNAIGND 238 Query: 230 --ATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGA 287 + WA ++ + + + Q I+ R ++ ++ + ++ G+ +G++ ++GA Sbjct: 239 QASVPWAVLLTGLLFNNLFYWCTNQS-IIQRTLAAKNLAEGQK-GVLFAGMFK---IFGA 293 Query: 288 FFAGFLGFALVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVA 347 F G + + + P++ I +P ++GF+ A + A++S+ ++ L + Sbjct: 294 AFLVLPGIIAYLLYGDVLANADMAYPSLVIDVMPVALSGFLAAVLFGAILSSFNNVLNSS 353 Query: 348 SSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIY 396 + DIY + + ++V RI A +A+ A+ + P ++Y Sbjct: 354 ITLFTLDIYKPIFKPNAKEPELVKAGRIFAACLAITAV---VIAPFILY 399 >pir||C69903 proline permease homolog yodF - Bacillus subtilis >gi|2415386|gb|AAB72054.1| (AF015775) permease [Bacillus subtilis] >gi|2634350|emb|CAB13849.1| (Z99114) similar to proline permease [Bacillus subtilis] Length = 496 Score = 100 bits (247), Expect = 4e-20 Identities = 106/443 (23%), Positives = 193/443 (42%), Gaps = 39/443 (8%) Query: 11 IYLVILAYIGWWA--NKYTKTE-DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAF 67 I ++ + IG+ A +K ++T +++ VGGR+ L A ++ + LG +AF Sbjct: 13 IIVLTVVCIGFLAGRDKSSRTSVEEWSVGGRRFGGLLVWFLVGADLYTAYTFLGLTSTAF 72 Query: 68 KAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSA 127 G AF+A + Y + P+L A + TL DY AR + N+KL+ L A Sbjct: 73 TGGSVAFFAIPYSVLAYFIAYFFL-PKLWKVAKIHKLTTLADY--ARERFNSKLLASLVA 129 Query: 128 AIILVFMTAYVAAQFAAGGKTFAQAFN--VSVTTGILITVIILTAYVITGGFFAVVWTDV 185 + ++ + Y+ Q + T A ++V ++I+ I++ Y G +T + Sbjct: 130 IVGVLMLIPYICLQLSGIQDTLQVAGTGYINVKFVVIISFILVALYTFFSGIKGPTYTAI 189 Query: 186 VQAMFMLLTLIIMPI-LALVEIGGLDRATQIIASVDPNKLH-PFGGATG--W---AAIVF 238 ++ + + + ++ M + L L+ G + P L P G G W A+IV Sbjct: 190 IKDILVWVIMLFMVVSLPLIHFNGWTPMIDTLVKEAPQMLTIPSEGPKGIPWFITASIVS 249 Query: 239 AIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALV 298 A+ W H T + + +R+ +F+ IVL F GF+ F ++ Sbjct: 250 ALALFMWA-------HAATGVFTAKSADAVRKNSMFLP--LYNIVLILVIFLGFIAFLVL 300 Query: 299 ASGSIKVEDPERIVPAMAIHFL-----PGWVAGFVIAGIISAVMSTADSQLLVASSAIAR 353 PE P +A+ L G GF A I A + + AS+ A Sbjct: 301 ---------PEDTNPRLALLHLIQTSYGGVAQGFAYATIALASLIPCSIMAIGASNLFAN 351 Query: 354 DIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPI 413 ++Y ++ + + ++ ++R +V V +A+ F + P + + G+ F P Sbjct: 352 NLYRDLIHPNVSQSKLTLVTRSMVFVVIGLALLFGMLFPTALVTLQLLGVSGMVQIF-PA 410 Query: 414 LTLSLWWKRVTKEAGIVGMAYGL 436 + +SL+WK TKEA ++G+ GL Sbjct: 411 IAVSLFWKNQTKEATVIGLLAGL 433 >emb|CAC17810.1| (AJ276242) sodium iodide symporter [Sus scrofa] Length = 643 Score = 99.5 bits (244), Expect = 9e-20 Identities = 114/457 (24%), Positives = 190/457 (40%), Gaps = 52/457 (11%) Query: 9 FLIYLVILAYIGWW---ANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65 F + L++ IG W A ++ + +F GGR++ + LS AS S +LG P Sbjct: 20 FALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLTAVPVGLSLSASFMSAVQVLGVPAE 79 Query: 66 AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRIL 125 A++ GL W +G L +L LL P + + YLE R ++ +R+ Sbjct: 80 AYRYGLKFLWMCLGQLLNSLLTALLFLPVFY----RLGLTSTYQYLELRF---SRAVRLC 132 Query: 126 SAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDV 185 LV Y A Q + + +L T II T Y GG AV+WTDV Sbjct: 133 GTLQYLVATMLYTGVVIYAPALILNQVTGLDIWASLLSTGIICTFYTTVGGMKAVIWTDV 192 Query: 186 VQAMFMLLTLIIMPILALVEIGGLDRATQIIAS----------VDPNKLHPFGGATGWAA 235 Q + ML ++ V +GG R ++ + +DP + + F W Sbjct: 193 FQVLVMLTGFWVVLARGTVLVGGPGRVLELAKNHSRINLMDFDLDPRRRYTF-----WTF 247 Query: 236 IVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGF 295 +V G W+ Y V RY++ K + + I+ + +++ A G + F Sbjct: 248 VVG--GTLVWLSMYGVNQAQVQRYVACR-TEKQAKLALLINQVGLFLIVSSAAACGIVMF 304 Query: 296 AL------VASGSIKVEDPERIVPAMAIHF---LPGWVAGFVIAGIISAVMSTADSQLLV 346 AL + +G I P++ +P + + LPG V G +A S +STA + + Sbjct: 305 ALYVDCDPLLAGHISA--PDQYMPLLVLDIFEDLPG-VPGLFLACAYSGTLSTASTSINA 361 Query: 347 ASSAIARDIYHKVLGQELGKKQMVNISR----IVVAAVALVAMWFAITGPKVIYQMVATA 402 ++ D+ L L +++V IS+ I +A VA ++ G V+ Q T Sbjct: 362 MAAVTVEDLIKPRL-PNLAPRRLVIISKGLSLIYGSACLTVAALSSLLGGGVL-QGSFTV 419 Query: 403 WGGLAVGFGPIL---TLSLWWKRVTKEAGIVGMAYGL 436 G ++ GP+L L ++ + G+A GL Sbjct: 420 MGVIS---GPLLGAFVLGMFLPSCNTSGVLSGLAAGL 453 >emb|CAC17816.1| (AJ276292) sodium iodide symporter [Sus scrofa] Length = 636 Score = 99.5 bits (244), Expect = 9e-20 Identities = 114/457 (24%), Positives = 190/457 (40%), Gaps = 52/457 (11%) Query: 9 FLIYLVILAYIGWW---ANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65 F + L++ IG W A ++ + +F GGR++ + LS AS S +LG P Sbjct: 20 FALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLTAVPVGLSLSASFMSAVQVLGVPAE 79 Query: 66 AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRIL 125 A++ GL W +G L +L LL P + + YLE R ++ +R+ Sbjct: 80 AYRYGLKFLWMCLGQLLNSLLTALLFLPVFY----RLGLTSTYQYLELRF---SRAVRLC 132 Query: 126 SAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDV 185 LV Y A Q + + +L T II T Y GG AV+WTDV Sbjct: 133 GTLQYLVATMLYTGVVIYAPALILNQVTGLDIWASLLSTGIICTFYTTVGGMKAVIWTDV 192 Query: 186 VQAMFMLLTLIIMPILALVEIGGLDRATQIIAS----------VDPNKLHPFGGATGWAA 235 Q + ML ++ V +GG R ++ + +DP + + F W Sbjct: 193 FQVLVMLTGFWVVLARGTVLVGGPGRVLELAKNHSRINLMDFDLDPRRRYTF-----WTF 247 Query: 236 IVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGF 295 +V G W+ Y V RY++ K + + I+ + +++ A G + F Sbjct: 248 VVG--GTLVWLSMYGVNQAQVQRYVACR-TEKQAKLALLINQVGLFLIVSSAAACGIVMF 304 Query: 296 AL------VASGSIKVEDPERIVPAMAIHF---LPGWVAGFVIAGIISAVMSTADSQLLV 346 AL + +G I P++ +P + + LPG V G +A S +STA + + Sbjct: 305 ALYVDCDPLLAGHISA--PDQYMPLLVLDIFEDLPG-VPGLFLACAYSGTLSTASTSINA 361 Query: 347 ASSAIARDIYHKVLGQELGKKQMVNISR----IVVAAVALVAMWFAITGPKVIYQMVATA 402 ++ D+ L L +++V IS+ I +A VA ++ G V+ Q T Sbjct: 362 MAAVTVEDLIKPRL-PNLAPRRLVIISKGLSLIYGSACLTVAALSSLLGGGVL-QGSFTV 419 Query: 403 WGGLAVGFGPIL---TLSLWWKRVTKEAGIVGMAYGL 436 G ++ GP+L L ++ + G+A GL Sbjct: 420 MGVIS---GPLLGAFVLGMFLPSCNTSGVLSGLAAGL 453 >gb|AAB81169.1| (AF006665) YolC [Bacillus subtilis] Length = 496 Score = 99.1 bits (243), Expect = 1e-19 Identities = 105/443 (23%), Positives = 192/443 (42%), Gaps = 39/443 (8%) Query: 11 IYLVILAYIGWWA--NKYTKTE-DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAF 67 I ++ + IG+ A +K ++T +++ VGGR+ L A ++ + LG + F Sbjct: 13 IIVLTVVCIGFLAGRDKSSRTSVEEWSVGGRRFGGLLVWFLVGADLYTAYTFLGLTSTTF 72 Query: 68 KAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSA 127 G AF+A + Y + P+L A + TL DY AR + N+KL+ L A Sbjct: 73 TGGSVAFFAIPYSVLAYFIAYFFL-PKLWKVAKIHKLTTLADY--ARERFNSKLLASLVA 129 Query: 128 AIILVFMTAYVAAQFAAGGKTFAQAFN--VSVTTGILITVIILTAYVITGGFFAVVWTDV 185 + ++ + Y+ Q + T A ++V ++I+ I++ Y G +T + Sbjct: 130 IVGVLMLIPYICLQLSGIQDTLQVAGTGYINVKFVVIISFILVALYTFFSGIKGPTYTAI 189 Query: 186 VQAMFMLLTLIIMPI-LALVEIGGLDRATQIIASVDPNKLH-PFGGATG--W---AAIVF 238 ++ + + + ++ M + L L+ G + P L P G G W A+IV Sbjct: 190 IKDILVWVIMLFMVVSLPLIHFNGWTPMIDTLVKEAPQMLTIPSEGPKGIPWFITASIVS 249 Query: 239 AIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALV 298 A+ W H T + + +R+ +F+ IVL F GF+ F ++ Sbjct: 250 ALALFMWA-------HAATGVFTAKSADAVRKNSMFLP--LYNIVLILVIFLGFIAFLVL 300 Query: 299 ASGSIKVEDPERIVPAMAIHFL-----PGWVAGFVIAGIISAVMSTADSQLLVASSAIAR 353 PE P +A+ L G GF A I A + + AS+ A Sbjct: 301 ---------PEDTNPRLALLHLIQTSYGGVAQGFAYATIALASLIPCSIMAIGASNLFAN 351 Query: 354 DIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPI 413 ++Y ++ + + ++ ++R +V V +A+ F + P + + G+ F P Sbjct: 352 NLYRDLIHPNVSQSKLTLVTRSMVFVVIGLALLFGMLFPTALVTLQLLGVSGMVQIF-PA 410 Query: 414 LTLSLWWKRVTKEAGIVGMAYGL 436 + +SL+WK TKEA ++G+ GL Sbjct: 411 IAVSLFWKNQTKEATVIGLLAGL 433 >pir||T35201 probable transmembrane transport - Streptomyces coelicolor >gi|3036892|emb|CAA18525.1| (AL022374) SC5B8.17, probable transmembrane transport protein, len: 530 aa; member of the sodium:solute symporter family, similar to many e.g. YJCG_ECOLI P32705 hypothetical protein , (549 aa), fasta scores; opt: 935 z-score: 1534.8 E(): 0, 43.6% ident> Length = 530 Score = 99.1 bits (243), Expect = 1e-19 Identities = 110/456 (24%), Positives = 187/456 (40%), Gaps = 41/456 (8%) Query: 14 VILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGA 73 V L W + + ++++ GGR + + S LG G G Sbjct: 19 VTLGITTWVGRRRQGSAEEFYAGGRLFSPMENGFAISGDYMSAASFLGISGLIALNGYDG 78 Query: 74 FWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAAIILVF 133 +G L L L+ +R G+F TL D + AR+++ +RI + + Sbjct: 79 MLYSVGFLVAWLVVLFLVAELVR-NCGRF---TLADVVAARMRERP--VRIAAGTSSVTV 132 Query: 134 MTAYVAAQFAAGGKTFAQAFNVSVTTGILITVI----ILTAYVITGGFFAVVWTDVVQAM 189 Y+ AQ G A + TVI ++ YV GG A W +V+A+ Sbjct: 133 SVLYLVAQMVGAGSLVALLLGGTSEAARTWTVIGVGALMVIYVSLGGMRATTWIQIVKAV 192 Query: 190 FMLLTLIIMPILALVEI-GGLDRATQIIASVDPNK---LHP---FGGATGWAAIVFAIGY 242 +L + + L LV G +DR + A + L P +GG W A I Sbjct: 193 LLLGGTVALTALVLVRFHGDVDRLLRTAAERSGHGEAFLAPGLAYGG--DWVARFDFISL 250 Query: 243 A-SWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFF-----AGFLGFA 296 + ++G G PHI++R+ +V R RR S +W +I L G F+ GF A Sbjct: 251 GLALVLGTAGLPHILSRFYTVPTARAARR-----SVVW-SIGLIGGFYLMTIVLGFGAAA 304 Query: 297 LVASGSIKVEDP--ERIVPAMAI------HFLPGWVAGFVIAGIISAVMSTADSQLLVAS 348 LV +++ + VP +A+ H G V V+A + A + + + +AS Sbjct: 305 LVGPNAVRASNAAGNTAVPLLALDLGGGAHSTGGTVLFAVVAAVAFATILAVVAGITLAS 364 Query: 349 SA-IARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKV-IYQMVATAWGGL 406 SA +A D+Y + + + V ++R+ + VA+ + + + +V A+ Sbjct: 365 SASVAHDLYASLRRRHSKPRSEVAVARVAAVGIGAVAIGLGLLARDLNVAFLVGLAFAVA 424 Query: 407 AVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVIL 442 A P+L SL+W+ T + + GL+ V+L Sbjct: 425 ASANLPVLLYSLFWRGFTTRGAVWAVYGGLVPSVVL 460 >gb|AAG01741.1|AF251267_1 (AF251267) low affinity sodium-glucose cotransporter [Mus musculus] Length = 656 Score = 95.2 bits (233), Expect = 2e-18 Identities = 118/536 (22%), Positives = 224/536 (41%), Gaps = 63/536 (11%) Query: 10 LIYLVILAYIGWWANKYTK--TEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAF 67 +IY V++ +G WA T T +F+ GR + S AS+ +G G+ Sbjct: 33 VIYFVVVMAVGVWAMLKTNRSTVGGFFLAGRSMTWWPMGASLFASNIGSGHFVGLAGTGA 92 Query: 68 KAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSA 127 +G+ A A F L I + I AG +T+P+YL+ R +L LS Sbjct: 93 ASGI-AVTAFESHSFALLLVLGWIFVPIYIKAG---VMTMPEYLKKRF-GGKRLQIYLSI 147 Query: 128 AIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQ 187 + + + ++A +G A +++ ILI + I + ITGG +V++TD VQ Sbjct: 148 LFLFICVILTISADIFSGAIFIKLALGLNLYLAILILLAITAIFTITGGLASVIYTDTVQ 207 Query: 188 AMFMLLTLIIMPILALVEIGGLDRATQ----IIASV---------------DPNKLH--- 225 A+ ML+ I+ + A VE+GG + T+ I SV P+ H Sbjct: 208 AVIMLVGSFILMVFAFVEVGGYESFTEKFMNAIPSVVEGDNLTINSRCYTPQPDSFHIFR 267 Query: 226 -PFGGATGWAAIVFAIGYAS---WIV--------------GYLGQPHIVTRYMSVEDPRK 267 P G W F + + W + ++ I+ Y+ + Sbjct: 268 DPVTGDIPWPGTAFGMPITALWYWCINQVIVQRCLCGKNLSHVKAACILCGYLKLLPLFF 327 Query: 268 LRRPGIFISGIWTTIVLWGAFFAGFLGFALVASGSIKVEDPERIVPAMAIHFLPGWVAGF 327 + PG+ ++T +V A + V + V P + + +P + G Sbjct: 328 MVMPGMISRILYTDMV------ACVVPSECVKHCGVDVGCTNYAYPMLVLKLMPPGLRGL 381 Query: 328 VIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVA-MW 386 +++ +++++MS+ S AS+ D+Y K+ ++ +++++ R+ V+ + + + +W Sbjct: 382 MLSVMLASLMSSLTSVFNSASTLFTIDLYTKI-RKKASERELLIAGRLFVSVLIVTSILW 440 Query: 387 FAIT-----GPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVI 441 I G V Y +++ G + + ++++ KR ++ G+ GL+ +I Sbjct: 441 VPIVEVSQGGQLVHYTEAISSYLGPPI--AAVFLVAVFCKRANEQGAFWGLMVGLVMGLI 498 Query: 442 LEAKIYGWAFNP-KAPGFFGTLGQWFNGVPVFFINFFVTLFIIIIVSLLTKPPEDV 496 + + AP + + + I FFV + +I+ VS LTKP DV Sbjct: 499 RMIAEFSYGTGSCLAPSSCPKIICGVHYLYFAIILFFVCILVILGVSYLTKPIPDV 554 >pir||E72071 hypothetical proline permease - Chlamydophila pneumoniae (strain CWL029) >gi|4376772|gb|AAD18626.1| (AE001634) hypothetical proline permease [Chlamydophila pneumoniae CWL029] >gi|8978856|dbj|BAA98692.1| (AP002546) hypothetical proline permease [Chlamydophila pneumoniae J138] Length = 460 Score = 95.2 bits (233), Expect = 2e-18 Identities = 111/443 (25%), Positives = 198/443 (44%), Gaps = 58/443 (13%) Query: 1 MNFGILFGFLIYLV-ILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLM 59 MNF + FLI + I Y+G +K + + YF+ GR + + ++ A+ G ++ Sbjct: 17 MNFSLFLFFLIAIQGICLYVGRRGSKKVEDRESYFLAGRSLKIFPLMMTFIATQIGGGVL 76 Query: 60 LGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNT 119 LG AF G G +G G + +L +GP R+ G + + K Sbjct: 77 LGAAEEAFCYGYGGILYPLGVALGLI--FLGMGPGKRLAEGSLTTVVSIFEVFYGSKKLR 134 Query: 120 KLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITV---IILTAYVITGG 176 K+ +LSA + + A V A + F+ S G +TV I+L +Y TGG Sbjct: 135 KIAFLLSAGSLFFILVAQVIAL----DRLFS-----SFPFGKYVTVAFWIVLASYTSTGG 185 Query: 177 FFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAI 236 F VV TDV+QA F+L+ +++ + + + + ++ +DP + P + W + Sbjct: 186 FRGVVRTDVIQAGFLLIAVLVCGVSVWLSV------PKSLSVLDPFQSLPCAKLSNWIFM 239 Query: 237 VFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFA 296 ++ L + +V R ++ P++L+ + G ++L+ F FLG + Sbjct: 240 P--------MLFMLVEQDMVQRCVAASSPKRLQWAAV---GAGLVLLLFN-FIPLFLG-S 286 Query: 297 LVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI- 355 L A +K P ++ +A +F +A + A I A++STADS + S IA + Sbjct: 287 LGAKAGLKAGCP--LIDTIA-YFCNPSLAAVMAAAIGVAILSTADSLMNAVSQLIAEEYP 343 Query: 356 -----YHK--VLGQELGKKQM----VNISRIVVAAVAL------VAMWFAITGPKVIYQM 398 Y++ VLG + + NI +++ + +L V + F + PK Sbjct: 344 TLKAPYYRYLVLGLAVAAPLVAIGFTNIVDVLILSYSLSVCCLSVPVGFYLLAPKGRRVS 403 Query: 399 VATAWGGL---AVGFGPILTLSL 418 A AW G+ A+G+G + +SL Sbjct: 404 GAAAWAGVLVGALGYGWVQIVSL 426 >gb|AAF73651.1| (AE002186) sodium:solute symporter family protein [Chlamydophila pneumoniae AR39] Length = 444 Score = 95.2 bits (233), Expect = 2e-18 Identities = 111/443 (25%), Positives = 198/443 (44%), Gaps = 58/443 (13%) Query: 1 MNFGILFGFLIYLV-ILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLM 59 MNF + FLI + I Y+G +K + + YF+ GR + + ++ A+ G ++ Sbjct: 1 MNFSLFLFFLIAIQGICLYVGRRGSKKVEDRESYFLAGRSLKIFPLMMTFIATQIGGGVL 60 Query: 60 LGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNT 119 LG AF G G +G G + +L +GP R+ G + + K Sbjct: 61 LGAAEEAFCYGYGGILYPLGVALGLI--FLGMGPGKRLAEGSLTTVVSIFEVFYGSKKLR 118 Query: 120 KLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITV---IILTAYVITGG 176 K+ +LSA + + A V A + F+ S G +TV I+L +Y TGG Sbjct: 119 KIAFLLSAGSLFFILVAQVIAL----DRLFS-----SFPFGKYVTVAFWIVLASYTSTGG 169 Query: 177 FFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAI 236 F VV TDV+QA F+L+ +++ + + + + ++ +DP + P + W + Sbjct: 170 FRGVVRTDVIQAGFLLIAVLVCGVSVWLSV------PKSLSVLDPFQSLPCAKLSNWIFM 223 Query: 237 VFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFA 296 ++ L + +V R ++ P++L+ + G ++L+ F FLG + Sbjct: 224 P--------MLFMLVEQDMVQRCVAASSPKRLQWAAV---GAGLVLLLFN-FIPLFLG-S 270 Query: 297 LVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI- 355 L A +K P ++ +A +F +A + A I A++STADS + S IA + Sbjct: 271 LGAKAGLKAGCP--LIDTIA-YFCNPSLAAVMAAAIGVAILSTADSLMNAVSQLIAEEYP 327 Query: 356 -----YHK--VLGQELGKKQM----VNISRIVVAAVAL------VAMWFAITGPKVIYQM 398 Y++ VLG + + NI +++ + +L V + F + PK Sbjct: 328 TLKAPYYRYLVLGLAVAAPLVAIGFTNIVDVLILSYSLSVCCLSVPVGFYLLAPKGRRVS 387 Query: 399 VATAWGGL---AVGFGPILTLSL 418 A AW G+ A+G+G + +SL Sbjct: 388 GAAAWAGVLVGALGYGWVQIVSL 410 >emb|CAB95932.1| (AL359989) putative sodium:solute symporter [Streptomyces coelicolor A3(2)] Length = 562 Score = 93.6 bits (229), Expect = 5e-18 Identities = 97/458 (21%), Positives = 190/458 (41%), Gaps = 35/458 (7%) Query: 11 IYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAG 70 IY V++ IG+ A + +T +F+ GR + L+ A++ +LG ++ + G Sbjct: 28 IYFVVVLGIGFAARRSVRTSLDFFLSGRSLPAWVTGLAFVAANLGATEILGMAANSAQYG 87 Query: 71 L-GAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAAI 129 + W IG + + L++ P Y K R++ P++L R K +LS+A+ Sbjct: 88 VYTTHWYWIGAIPAMVFLGLVMMPFY--YGSKVRSV--PEFLLLRFD---KASHLLSSAL 140 Query: 130 ILVFMTAYVAAQFAAGGKTFAQAFNVSVTTG------ILITVIILTAYVITGGFFAVVWT 183 + AA AG +A A V G I++ + AY+ GG + ++ Sbjct: 141 FAI------AAILIAGVNLYALAIVVEALLGWPEWVAIVVAGFFVLAYITLGGLSSAIYN 194 Query: 184 DVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATG----------W 233 +V+Q +L LI + IL L ++GG D + ++ + G TG W Sbjct: 195 EVLQFFVILAGLIPITILGLKKVGGWDGLSDSLSKSHGSDFMTAWGGTGIGSENPLGANW 254 Query: 234 AAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFL 293 IV +G+ + V R +S ++ +R + I+ +++ G + Sbjct: 255 LTIVLGLGFVLSFGYWTTNFAEVQRALSAKNLSAAQRTPL-IAAFPKIFIVFVVMIPGLV 313 Query: 294 GFALVASGSIKVEDPE--RIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAI 351 LV D + +P + LP V G + G+++A M+ + + ++ Sbjct: 314 AAVLVPKIGTPGSDLQYNDAIPYLMQQLLPNGVLGIAVTGLLAAFMAGMAANISSFNTVF 373 Query: 352 ARDIYHKVLGQELGKKQMVNISRI--VVAAVALVAMWFAITGPKVIYQMVATAWGGLAVG 409 DI+ K + ++ V R+ V+ +A + F + I + T + V Sbjct: 374 TTDIWQKYVVKDREDGYYVRFGRLITVIGVLASIGTAFLASSFSNIMSYLQTLFSFFNVP 433 Query: 410 FGPILTLSLWWKRVTKEAGIVGMAYGLISEVILEAKIY 447 + + ++WKR + ++G G+ G + ++ IY Sbjct: 434 MFVVFIIGMFWKRASMKSGFWGLIAGTTAAMVNYFVIY 471 >gi|6981552 solute carrier family 5, member alpha 1 (Na+/glucose cotransporter) [Rattus norvegicus] >gi|1709218|sp|P53790|SL51_RAT SODIUM/GLUCOSE COTRANSPORTER 1 (NA(+)/GLUCOSE COTRANSPORTER 1) (HIGH AFFINITY SODIUM-GLUCOSE COTRANSPORTER) >gi|1083725|pir||A53582 Na+/glucose cotransporter SGLT1 - rat >gi|286259|dbj|BAA03676.1| (D16101) Sodium/glucose cotransporter [Rattus norvegicus] >gi|414572|gb|AAA19015.1| (U03120) sodium-glucose cotransporter 1 [Rattus norvegicus] Length = 665 Score = 93.2 bits (228), Expect = 7e-18 Identities = 122/538 (22%), Positives = 220/538 (40%), Gaps = 67/538 (12%) Query: 10 LIYLVILAYIGWWANKYTK--TEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAF 67 +IY V++ +G WA T T +F+ GR + S AS+ +G G+ Sbjct: 33 VIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGA 92 Query: 68 KAGL---GAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRI 124 AG+ G W + +F + +L + + I AG +T+P+YL R K I+I Sbjct: 93 AAGIAMGGFEWNAL--VFVVVLGWLFVP--IYIKAG---VVTMPEYLRKRF--GGKRIQI 143 Query: 125 -LSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 LS +L+++ ++A +G A + + I I + I Y ITGG AV++T Sbjct: 144 YLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLAAVIYT 203 Query: 184 DVVQAMFMLLTLIIMPILALVEIGG----LDRATQIIASV--DPN-------------KL 224 D +Q ML+ I+ A E+GG +D+ + I ++ D N Sbjct: 204 DTLQTAIMLVGSFILTGFAFREVGGYEAFMDKYMKAIPTLVSDGNITVKEECYTPRADSF 263 Query: 225 H----PFGGATGWAAIVFAIG-YASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIW 279 H P G W ++F + A W + IV R +S ++ + + G + G Sbjct: 264 HIFRDPITGDMPWPGLIFGLSILALWY--WCTDQVIVQRCLSAKNMSHV-KAGCTLCGYL 320 Query: 280 TTIVLWGAFFAGFLG-------FALVASGSIK------VEDPERIVPAMAIHFLPGWVAG 326 + ++ G + A V K V P + + +P + G Sbjct: 321 KLLPMFLMVMPGMISRILYTDKIACVLPSECKKYCGTPVGCTNIAYPTLVVELMPNGLRG 380 Query: 327 FVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMW 386 +++ +++++MS+ S AS+ DIY K+ K+ M+ ++ + + W Sbjct: 381 LMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKGASEKELMIAGRLFILVLIGISIAW 440 Query: 387 FAITGPK---VIYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGL---ISEV 440 I ++ + + L + L+++ KRV + G+ G IS + Sbjct: 441 VPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPGAFWGLILGFLIGISRM 500 Query: 441 ILE-AKIYGWAFNP-KAPGFFGTLGQWFNGVPVFFINFFVTLFIIIIVSLLTKPPEDV 496 I E A G P P + + + I F +++ ++++SLLTKP DV Sbjct: 501 ITEFAYGTGSCMEPSNCPKIICGVHYLYFAI----ILFAISVVTVLVISLLTKPIPDV 554 >dbj|BAA19172.1| (AB000729) Na/glucose cotransporter [Rattus norvegicus] Length = 665 Score = 93.2 bits (228), Expect = 7e-18 Identities = 122/538 (22%), Positives = 220/538 (40%), Gaps = 67/538 (12%) Query: 10 LIYLVILAYIGWWANKYTK--TEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAF 67 +IY V++ +G WA T T +F+ GR + S AS+ +G G+ Sbjct: 33 VIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGA 92 Query: 68 KAGL---GAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRI 124 AG+ G W + +F + +L + + I AG +T+P+YL R K I+I Sbjct: 93 AAGIAMGGFEWNAL--VFVVVLGWLFVP--IYIKAG---VVTMPEYLRKRF--GGKRIQI 143 Query: 125 -LSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWT 183 LS +L+++ ++A +G A + + I I + I Y ITGG AV++T Sbjct: 144 YLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLAAVIYT 203 Query: 184 DVVQAMFMLLTLIIMPILALVEIGG----LDRATQIIASV--DPN-------------KL 224 D +Q ML+ I+ A E+GG +D+ + I ++ D N Sbjct: 204 DTLQTAIMLVGSFILTGFAFREVGGYEAFMDKYMKAIPTLVSDGNITVKEECYTPRADSF 263 Query: 225 H----PFGGATGWAAIVFAIG-YASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIW 279 H P G W ++F + A W + IV R +S ++ + + G + G Sbjct: 264 HIFRDPITGDMPWPGLIFGLSILALWY--WCTDQVIVQRCLSAKNMSHV-KAGCTLCGYL 320 Query: 280 TTIVLWGAFFAGFLG-------FALVASGSIK------VEDPERIVPAMAIHFLPGWVAG 326 + ++ G + A V K V P + + +P + G Sbjct: 321 KLLPMFLMVMPGMISRILYTDKIACVLPSECKKHCGTPVGCTNIAYPTLVVELMPNGLRG 380 Query: 327 FVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMW 386 +++ +++++MS+ S AS+ DIY K+ K+ M+ ++ + + W Sbjct: 381 LMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKGASEKELMIAGRLFILVLIGISIAW 440 Query: 387 FAITGPK---VIYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGL---ISEV 440 I ++ + + L + L+++ KRV + G+ G IS + Sbjct: 441 VPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPGAFWGLILGFLIGISRM 500 Query: 441 ILE-AKIYGWAFNP-KAPGFFGTLGQWFNGVPVFFINFFVTLFIIIIVSLLTKPPEDV 496 I E A G P P + + + I F +++ ++++SLLTKP DV Sbjct: 501 ITEFAYGTGSCMEPSNCPKIICGVHYLYFAI----ILFAISVVTVLVISLLTKPIPDV 554 >gi|4507035 solute carrier family 5 (sodium iodide symporter), member 5 [Homo sapiens] >gi|11526040|ref|XP_009295.1| solute carrier family 5 (sodium iodide symporter), member 5 [Homo sapiens] >gi|2136179|pir||JC4974 sodium iodide symporter - human >gi|1628579|gb|AAB17378.1| (U66088) sodium iodide symporter [Homo sapiens] >gi|3702269|gb|AAC62827.1| (AC005796) sodium iodide symporter [Homo sapiens] Length = 643 Score = 92.4 bits (226), Expect = 1e-17 Identities = 111/452 (24%), Positives = 184/452 (40%), Gaps = 54/452 (11%) Query: 9 FLIYLVILAYIGWW---ANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65 F + L++ IG W A ++ + +F GGR++ L LS AS S +LG P Sbjct: 20 FALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLGVPSE 79 Query: 66 AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRIL 125 A++ GL W +G L ++ LL P + + +YLE R ++ +R+ Sbjct: 80 AYRYGLKFLWMCLGQLLNSVLTALLFMPVFY----RLGLTSTYEYLEMRF---SRAVRLC 132 Query: 126 SAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDV 185 +V Y A Q + + +L T II T Y GG AVVWTDV Sbjct: 133 GTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWTDV 192 Query: 186 VQAMFMLLTLIIMPILALVEIGG------LDRATQIIASVDPNKLHPFGGATGWAAIVFA 239 Q + ML ++ ++ +GG L + I +D N P T W +V Sbjct: 193 FQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNP-DPRSRYTFWTFVVG- 250 Query: 240 IGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVA 299 G W+ Y V RY++ K + + I+ + +++ A G + F Sbjct: 251 -GTLVWLSMYGVNQAQVQRYVACR-TEKQAKLALLINQVGLFLIVSSAACCGIVMFVFYT 308 Query: 300 SGSI----KVEDPERIVPAMAIHF---LPGWVAGFVIAGIISAVMSTADSQLLVASSAIA 352 ++ P++ +P + + LPG V G +A S +STA + + ++ Sbjct: 309 DCDPLLLGRISAPDQYMPLLVLDIFEDLPG-VPGLFLACAYSGTLSTASTSINAMAAVTV 367 Query: 353 RDIYHKVLGQELGKKQMVNISR----------IVVAAVALV----------AMWFAITGP 392 D+ L + L +++V IS+ + VAA++ + + I+GP Sbjct: 368 EDLIKPRL-RSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGP 426 Query: 393 KV---IYQMVATAWG--GLAVGFGPILTLSLW 419 + I M A G+ G G L LSLW Sbjct: 427 LLGAFILGMFLPACNTPGVLAGLGAGLALSLW 458 >dbj|BAA24835.1| (D87920) sodium iodide symporter [Homo sapiens] Length = 643 Score = 92.1 bits (225), Expect = 1e-17 Identities = 111/452 (24%), Positives = 184/452 (40%), Gaps = 54/452 (11%) Query: 9 FLIYLVILAYIGWW---ANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65 F + L++ IG W A ++ + +F GGR++ L LS AS S +LG P Sbjct: 20 FALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLGVPSE 79 Query: 66 AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRIL 125 A++ GL W +G L ++ LL P + + +YLE R ++ +R+ Sbjct: 80 AYRYGLKFLWMCLGQLLNSVLTPLLFMPVFY----RLGLTSTYEYLEMRF---SRAVRLC 132 Query: 126 SAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDV 185 +V Y A Q + + +L T II T Y GG AVVWTDV Sbjct: 133 GTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWTDV 192 Query: 186 VQAMFMLLTLIIMPILALVEIGG------LDRATQIIASVDPNKLHPFGGATGWAAIVFA 239 Q + ML ++ ++ +GG L + I +D N P T W +V Sbjct: 193 FQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNP-DPRSRYTFWTFVVG- 250 Query: 240 IGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVA 299 G W+ Y V RY++ K + + I+ + +++ A G + F Sbjct: 251 -GTLVWLSMYGVNQAQVQRYVACR-TEKQAKLALLINQVGLFLIVSSAACCGIVMFVFYT 308 Query: 300 SGSI----KVEDPERIVPAMAIHF---LPGWVAGFVIAGIISAVMSTADSQLLVASSAIA 352 ++ P++ +P + + LPG V G +A S +STA + + ++ Sbjct: 309 DCDPLLLGRISAPDQYMPLLVLDIFEDLPG-VPGLFLACAYSGTLSTASTSINAMAAVTV 367 Query: 353 RDIYHKVLGQELGKKQMVNISR----------IVVAAVALV----------AMWFAITGP 392 D+ L + L +++V IS+ + VAA++ + + I+GP Sbjct: 368 EDLIKPRL-RSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGP 426 Query: 393 KV---IYQMVATAWG--GLAVGFGPILTLSLW 419 + I M A G+ G G L LSLW Sbjct: 427 LLGAFILGMFLPACNTPGVLAGLGAGLALSLW 458 >emb|CAC00574.1| (AL109659) dJ1024N4.1 (novel Sodium:solute symporter family member similar to SLC5A1 (SGLT1)) [Homo sapiens] Length = 552 Score = 91.7 bits (224), Expect = 2e-17 Identities = 126/536 (23%), Positives = 225/536 (41%), Gaps = 69/536 (12%) Query: 10 LIYLVILAYIGWWANKYTK--TEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAF 67 +IY V + +G W++ T YF+ GR + S +S+ L +G G+ Sbjct: 35 VIYFVFVIAVGIWSSIRASRGTIGGYFLAGRSMSWWPIGASLMSSNVGSGLFIGLAGTGA 94 Query: 68 KAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSA 127 GL + LA + P + I AG +T+P YL+ R + + Sbjct: 95 AGGLAVGGFEWNATWLLLALGWVFVP-VYIAAG---VVTMPQYLKKRFGGQRIQVYMSVL 150 Query: 128 AIILVFMTAYVAAQFAAGGKTFAQ---AFNVSVTTGILITVIILTAYVITGGFFAVVWTD 184 ++IL T F+ G F Q +N+ ++TGIL+ ++ Y I GG AV++TD Sbjct: 151 SLILYIFTKISTDIFS--GALFIQMALGWNLYLSTGILL--VVTAVYTIAGGLMAVIYTD 206 Query: 185 VVQAMFMLLTLIIMPILALVEIG---GLD-RATQIIASVD----------PNKLH----P 226 +Q + M+ +++ L ++G GL+ R Q I +V P+ H P Sbjct: 207 ALQTVIMVGGALVLMFLGFQDVGWYPGLEQRYRQAIPNVTVPNTTCHLPRPDAFHILRDP 266 Query: 227 FGGATGWAAIVFAIG-YASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLW 285 G W ++F + A+W + IV R +S + + G + G + ++ Sbjct: 267 VSGDIPWPGLIFGLTVLATWC--WCTDQVIVQRSLSAKS-LSHAKGGSVLGGYLKILPMF 323 Query: 286 GAFFAGFLGFALVAS--GSIKVEDPERI-----------VPAMAIHFLPGWVAGFVIAGI 332 G + AL G + + +RI P + + +P + G +IA I Sbjct: 324 FIVMPGMISRALFPDEVGCVDPDVCQRICGARVGCSNIAYPKLVMALMPVGLRGLMIAVI 383 Query: 333 ISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAI--- 389 ++A+MS+ S +S+ D++ + + ++ MV VV V + +W I Sbjct: 384 MAALMSSLTSIFNSSSTLFTIDVWQRFRRKSTEQELMVVGRVFVVFLVVISILWIPIIQS 443 Query: 390 TGPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGL---ISEVILEAKI 446 + ++ + LA + L+++ KRVT+ G+ +GL + +ILE Sbjct: 444 SNSGQLFDYIQAVTSYLAPPITALFLLAIFCKRVTEPGAFWGLVFGLGVGLLRMILE--- 500 Query: 447 YGWAFNPKAPGFFGTLGQWFNGVPVFFINFF------VTLFIIIIVSLLTKP-PED 495 F+ AP G + + + F +F +T +I+IVSL T P PE+ Sbjct: 501 ----FSYPAPA-CGEVDRRPAVLKDFHYLYFAILLCGLTAIVIVIVSLCTTPIPEE 551 >pir||D72694 hypothetical protein APE0972 - Aeropyrum pernix (strain K1) >gi|5104641|dbj|BAA79956.1| (AP000060) 460aa long hypothetical protein [Aeropyrum pernix] Length = 460 Score = 90.1 bits (220), Expect = 6e-17 Identities = 90/400 (22%), Positives = 182/400 (45%), Gaps = 25/400 (6%) Query: 30 EDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYL 89 E ++++ GR++ + ++ A+ +S ++++G G A+ G+G+ + L T+ Sbjct: 5 EGEFYLAGRRLTGFLSAMTYAATTYSSFMIVGLVGLAYFTGIGSLVFELAYLVATVILLS 64 Query: 90 LIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKT- 148 L R+ + + R P + A L + + + ++ + LV + Y +AQ +T Sbjct: 65 LFSRRVWRMSRE-RGWVSPGEMLADLL-GSPWVALTASLVFLVSLVPYASAQLKGIAETI 122 Query: 149 -----FAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILAL 203 ++ N + + + ++IL A+ + G VV TD Q ++ML ++ + Sbjct: 123 VAIAGYSPGDNTAYMVAVGVALLILLAWSLLAGVRGVVLTDAFQGLWMLTAGSLLFLWLA 182 Query: 204 VEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYAS-WIVGYLGQPHIVTRYMSV 262 + A++++++++ L AT IG+ + W+ + P +V R Sbjct: 183 SRVFSKSGASEVLSAMESAGLFDMWSAT------LLIGFVTPWVFFAVTNPQVVQRLYMP 236 Query: 263 EDPRKLRRPGI--FISGIWTTIVLWGAFFAGFLGFALVASGSIKVEDPERI-VPAMAIHF 319 +D LRR + F+ G++ T+++ GFL A V G + +E R V + Sbjct: 237 KDEESLRRMILYFFLFGLYYTVLVVAI---GFLARAGVELGILSIEPQGRDQVTPQLLSL 293 Query: 320 LPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAA 379 +A V I++A +STADS +L +S+ +RDI VL L +K + + A Sbjct: 294 AHPLLAALVFTSIVAASVSTADSIILALASSASRDIGLLVL--RLDEKGRLRLGYAAAAL 351 Query: 380 VALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLW 419 ++ FA T I Q+ + + +G P+ T++ W Sbjct: 352 FTVLMAVFAATRIGYIVQLSVLS-SVMLLGLAPV-TIAAW 389 >emb|CAB94614.1| (AL359214) putative permease [Streptomyces coelicolor A3(2)] Length = 532 Score = 89.7 bits (219), Expect = 8e-17 Identities = 114/525 (21%), Positives = 214/525 (40%), Gaps = 59/525 (11%) Query: 1 MNFGILFGFLIYLVILAYIGWWANKYTKTE-----DQYFVGGRKVHVLAATLSDKASDFS 55 MN L F+ + V++ +G+ A ++ + E D++ +GGR ++ Sbjct: 1 MNGVALAVFIFFFVLVTAMGFLAARWRRAENEHSLDEWGLGGRSFGTWVTWFLLGGDLYT 60 Query: 56 GWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIG---PRLRIYAGKFRAITLPDYLE 112 + + P + + AG F+A + T+ Y LI PRL + K +T D++ Sbjct: 61 AYTFVAVPAAIYAAGASGFFA----VPYTILVYPLIFTFLPRLWSVSHKHGYVTTSDFVR 116 Query: 113 ARLKDNTKLIRILSAAIILVFMTAYVAAQFAA----------GGKTFAQAFNVSVTTGIL 162 R +K + + A ++ Y+A Q GG F + +L Sbjct: 117 GRF--GSKGLSLAVAVTGILATMPYIALQLVGIQAVLDVMGVGGGEDTNWFVKDLP--LL 172 Query: 163 ITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLD----RATQIIAS 218 I +L AY + G A V+ + + + + I +++GG D A+ + Sbjct: 173 IAFGVLAAYTYSSGLRAPALIAFVKDTLIYIVIAVAIIYIPIKLGGFDDIFASASDKFTA 232 Query: 219 VDPNKLHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGI 278 + P G W A+G A + Y PH +T +S +RR Sbjct: 233 AGKGGVVPDAGGQ-WTYATLALGSALALFMY---PHSITATLSSRSREVIRRN------- 281 Query: 279 WTTIVLWGAFFAGFL---GFALVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISA 335 TTI+ + G L GF +A+G +KV++ + +P + + P W AG A I Sbjct: 282 -TTILPLYSLMLGLLALLGFMAIAAG-VKVDNGQLAIPQLFENMFPDWFAGVAFAAIGIG 339 Query: 336 VMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVI 395 + A + A++ R+IY + + +Q +S++V V + A+ F + K + Sbjct: 340 ALVPAAIMSIAAANLFTRNIYKDFIKPDATPQQETKVSKLVSLLVKVGALIFVLGMDKTV 399 Query: 396 ---YQMVATAWGGLAVGFGPIL--TLSLWWKRVTKEAG-IVGMAYGLISE--VILEAKIY 447 +Q++ W + F ++ + W+ R G VGM YG ++ V + + Sbjct: 400 AINFQLLGGIW--ILQTFPALVGGLFTRWFHRWALLGGWAVGMVYGTVAAYGVASPTQKH 457 Query: 448 GWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTLFIIIIVSLLTKP 492 + + PG G +G + G+ F +N VT+ + ++ + P Sbjct: 458 FGGSSDEIPG-IGEIG--YIGLTAFVLNVLVTVVLTFVLRAVKAP 499 >gi|11498804 pantothenate permease (panF-2) [Archaeoglobus fulgidus] >gi|7442767|pir||D69400 pantothenate permease (panF-2) homolog - Archaeoglobus fulgidus >gi|2649380|gb|AAB90040.1| (AE001021) pantothenate permease (panF-2) [Archaeoglobus fulgidus] Length = 474 Score = 88.9 bits (217), Expect = 1e-16 Identities = 107/480 (22%), Positives = 196/480 (40%), Gaps = 37/480 (7%) Query: 10 LIYLVILAYIGWWANK-YTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFK 68 + +LV +G++ K K+E+ Y V R + + ++ + +LG SA+ Sbjct: 1 MYFLVTTLGVGFYLMKRMEKSEEDYLVAKRGLGAVPVGVTLALTVLGTPHILGVMESAYD 60 Query: 69 AGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAA 128 GL A W L G +A K + ++P++L+ + +R++ A Sbjct: 61 IGLPAVWFSFAHAIMLAIVCLFTGR----WARKLKVESVPEFLDVIFSNYW--LRLMVGA 114 Query: 129 IILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQA 188 +I + + G + S+ GI+I +I YV+ G V W +V+ A Sbjct: 115 VIAGAIFGICTLETQGLGVFVSILTGTSIEVGIVIGALIGILYVVLSGMKEVAWLNVLNA 174 Query: 189 MFMLLTLIIMP-ILALVEIGGLDRATQIIASVD-PNKLHPFGGATGWAAIV-FAIGYASW 245 + + + +I +L G + + S D KL+ FG W V FA+ Sbjct: 175 VILYIGIIAATFVLGSGLQNGWEGVNEFYISNDLAGKLNIFGS---WEVFVGFALVNVLA 231 Query: 246 IVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAF--FAGFLGFALVASGSI 303 V + G + + P + + + + G+F FA +G A A+ Sbjct: 232 TVFFQG-----ISQQGLHAALAAKSPDVLRKAMLIAVPVNGSFAVFAAVMGMAARATPEF 286 Query: 304 KVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQE 363 + PAM + LP W + ++A + AV+S+ LL ++ DIY VL Sbjct: 287 AELGAKTATPAMIVSVLPTWASALLLATCLVAVLSSYAITLLAPTTIFVNDIYKAVLKPN 346 Query: 364 LGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMV-ATAWGGLAVGFGPILTLSLWWKR 422 ++++ +SRI+ +A+ A+ A++ P ++ M+ +W V + L+WKR Sbjct: 347 ASHEELLRLSRILTVLLAVAALIPAVSLPPILAAMMWLFSW---LVPVFWFVIFGLFWKR 403 Query: 423 VTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFVTLFI 482 A +I+ +++ I W P P G G W + V ++ VTL I Sbjct: 404 SAPAA--------IITCLLVWVTINAWTMTP-LPEVLGAPG-WLHQV---YLALIVTLVI 450 >pir||S68513 thyroid iodide transport protein - rat >gi|1399954|gb|AAB03338.1| (U60282) thyroid sodium/iodide symporter NIS [Rattus norvegicus] Length = 618 Score = 87.4 bits (213), Expect = 4e-16 Identities = 111/453 (24%), Positives = 182/453 (39%), Gaps = 44/453 (9%) Query: 9 FLIYLVILAYIGWW---ANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGS 65 F L++ IG W A ++ D +F GGR++ + LS AS S +LG P Sbjct: 20 FATMLLVSTGIGLWVGLARGGQRSADDFFTGGRQLAAVPVGLSLAASFMSAVQVLGVPAE 79 Query: 66 AFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRIL 125 A + GL W G L +L L P + + YLE R ++ +R+ Sbjct: 80 AARYGLKFLWMCAGQLLNSLLTAFLFLPIFY----RLGLTSTYQYLELRF---SRAVRLC 132 Query: 126 SAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDV 185 LV Y A Q + + +L T II T Y GG AVVWTDV Sbjct: 133 GTLQYLVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTLYTTVGGMKAVVWTDV 192 Query: 186 VQAMFMLLTLIIMPILALVEIGGLDRATQI--------IASVDPNKLHPFGGATGWAAIV 237 Q + ML+ ++ ++ +GG + + DP+ P T W IV Sbjct: 193 FQVVVMLVGFWVILARGVILLGGPRNVLSLAQNHSRINLMDFDPD---PRSRYTFWTFIV 249 Query: 238 FAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFAL 297 G W+ Y V RY++ K + + ++ + +++ A G + F Sbjct: 250 G--GTLVWLSMYGVNQAQVQRYVACHTEGKAKL-ALLVNQLGLFLIVASAACCGIVMFVY 306 Query: 298 VASG----SIKVEDPERIVPAMAIHF---LPGWVAGFVIAGIISAVMSTADSQLLVASSA 350 + ++ P++ +P + + LPG V G +A S +STA + + ++ Sbjct: 307 YKDCDPLLTGRISAPDQYMPLLVLDIFEDLPG-VPGLFLACAYSGTLSTASTSINAMAAV 365 Query: 351 IARDIYHKVLGQELGKKQMVNISR----IVVAAVALVAMWFAITGPKVIYQMVATAWGGL 406 D+ K L +++V IS+ I +A VA ++ G V+ Q T G + Sbjct: 366 TVEDLI-KPRMPGLAPRKLVFISKGLSFIYGSACLTVAALSSLLGGGVL-QGSFTVMGVI 423 Query: 407 AVGFGPIL---TLSLWWKRVTKEAGIVGMAYGL 436 + GP+L TL + + G+A GL Sbjct: 424 S---GPLLGAFTLGMLLPACNTPGVLSGLAAGL 453 >pir||G83610 probable sodium:solute symporter PA0287 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9946130|gb|AAG03676.1|AE004466_10 (AE004466) probable sodium:solute symporter [Pseudomonas aeruginosa] Length = 461 Score = 87.4 bits (213), Expect = 4e-16 Identities = 106/463 (22%), Positives = 194/463 (41%), Gaps = 41/463 (8%) Query: 10 LIYLVILAYIGWWANKYTKTEDQYFVGGRKVH------VLAATLSDKASDFSGWLMLGYP 63 L+Y + + +GW+ + K++ + V GR++ +AA + AS G + LGY Sbjct: 9 LVYALAMLGLGWYGMRKAKSQSDFLVAGRRLGPGLYLGTMAAVVLGGASTI-GTVKLGY- 66 Query: 64 GSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIR 123 + GL W G + L+ ++ + R T+ LE R + +++LI Sbjct: 67 ----QFGLSGLWLVFMLGLGIIVLSLVFSRQI----ARLRVFTVTQVLEQRYQASSRLIG 118 Query: 124 --ILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVV 181 ++ A ++V +TA +A G F + IL I+ Y + GG +++ Sbjct: 119 GVVMVAYDLMVAVTATIAI-----GSVTEVVFGIPRIPAILCGGGIVIVYSVIGGMWSLT 173 Query: 182 WTDVVQAMFML--LTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFA 239 TD++Q + + L+++P L++ GGL R +++ P G + + Sbjct: 174 LTDIIQFVIKTVGIFLVLLP-LSIDGAGGLARMQEVL----PAGFFDLGHIGLDTILTYF 228 Query: 240 IGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVA 299 + Y G L I R + +R G+ G +L+GA A A V Sbjct: 229 LLY---FFGALIGQDIWQRVFTARSETVVRYAGL---GAGVYCMLYGAACALIGAAARVL 282 Query: 300 SGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKV 359 + V PE + L + G V+A +SA+MSTA LL A++ + DIY + Sbjct: 283 LPDLAV--PENAYAEITREVLAPGLRGLVVAAALSAIMSTASGCLLAAATVLQEDIYARF 340 Query: 360 LGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLW 419 L G + +SR + + + + A VI ++ A+ L G + +L Sbjct: 341 L--RPGTTSDIRLSRCITLLMGVAMLVLACLVNDVI-AALSIAYNLLVGGLLVPIVGALL 397 Query: 420 WKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTL 462 W+R + + I + G ++ + A+ A +P G +L Sbjct: 398 WRRASPQGAIASIVAGCLAVIACMARDGLLANSPIVYGLLASL 440 >sp|P23723|PUTP_KLEPN SODIUM/PROLINE SYMPORTER (PROLINE PERMEASE) >gi|443996|emb|CAA52889.1| (X74934) proline permease [Klebsiella pneumoniae] Length = 160 Score = 84.7 bits (206), Expect = 3e-15 Identities = 42/115 (36%), Positives = 64/115 (55%), Gaps = 1/115 (0%) Query: 5 ILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 +L F++Y+ + IG+ A + TK D Y +GGR + LS ASD SGWL++G PG Sbjct: 7 MLVTFIVYIFGMVLIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPG 66 Query: 65 SAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAG-KFRAITLPDYLEARLKDN 118 + F +G+ W IG G ++ L+ RLR++ A+T PDY R +D+ Sbjct: 67 AIFISGISESWIAIGLTLGAWINWKLVAGRLRVHTEVNNNALTXPDYFTGRFEDH 121 >prf||2204393A Na/I symporter [Rattus norvegicus] Length = 618 Score = 83.9 bits (204), Expect = 4e-15 Identities = 106/457 (23%), Positives = 183/457 (39%), Gaps = 41/457 (8%) Query: 2 NFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLG 61 ++G+ L+ + + A ++ D +F GGR++ + LS AS S +LG Sbjct: 16 DYGVFATMLLVSTGIGLMVGLARGGQRSADDFFTGGRQLAAVPVGLSLAASFMSAVQVLG 75 Query: 62 YPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKL 121 P A + GL W G L +L L P + + YLE R ++ Sbjct: 76 VPAEAARYGLKFLWMCAGQLLNSLLTAFLFLPIFY----RLGLTSTYQYLELRF---SRA 128 Query: 122 IRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVV 181 +R+ LV Y A Q + + +L T II T Y GG AVV Sbjct: 129 VRLCGTLQYLVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTLYTTVGGMKAVV 188 Query: 182 WTDVVQAMFMLLTLIIMPILALVEIGGLDRATQI--------IASVDPNKLHPFGGATGW 233 WTDV Q + ML+ ++ ++ +GG + + DP+ P T W Sbjct: 189 WTDVFQVVVMLVGFWVILARGVILLGGPRNVLSLAQNHSRINLMDFDPD---PRSRYTFW 245 Query: 234 AAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFL 293 + G W+ Y V RY++ K + + ++ + +++ A G + Sbjct: 246 T--FYVGGTLVWLSMYGVNQAQVQRYVACHTEGKAKL-ALLVNQLGLFLIVASAACCGIV 302 Query: 294 GFALVASG----SIKVEDPERIVPAMAIHF---LPGWVAGFVIAGIISAVMSTADSQLLV 346 F + ++ P++ +P + + LPG V G +A +S +STA + + Sbjct: 303 MFVYYKDCDPLLTGRISAPDQYMPLLVLDIFEDLPG-VPGLFLACAVSGTLSTASTSINA 361 Query: 347 ASSAIARDIYHKVLGQELGKKQMVNISR----IVVAAVALVAMWFAITGPKVIYQMVATA 402 ++ D+ K L +++V IS+ I +A VA ++ G V+ Q T Sbjct: 362 MAAVTVEDLI-KPRMPGLAPRKLVFISKGLSFIYGSACLTVAALSSLLGGGVL-QGSFTV 419 Query: 403 WGGLAVGFGPIL---TLSLWWKRVTKEAGIVGMAYGL 436 G ++ GP+L TL + + G+A GL Sbjct: 420 MGVIS---GPLLGAFTLGMLLPACNTPGVLSGLAAGL 453 >emb|CAC16517.1| (AL450223) putative integral membrane transport protein [Streptomyces coelicolor] Length = 523 Score = 83.5 bits (203), Expect = 6e-15 Identities = 110/509 (21%), Positives = 201/509 (38%), Gaps = 26/509 (5%) Query: 10 LIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKA 69 ++YL+ +A+IG K+ YFVG + + S A++ S ++ PG A+ Sbjct: 10 VVYLIGIAWIGLRKAGRQKSAKDYFVGEGHMPWWTVSFSVVATETSVLTVISVPGGAYSG 69 Query: 70 -GLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAA 128 G G +G + G + ++ P + G F ++ YL R KL + S Sbjct: 70 QGFGNVELALGYVVGRVVVATVLIPLYK--RGGF--VSAYQYLGDRF--GLKLQGLASVT 123 Query: 129 IILVFMTAYVAAQFAAGG--KTFAQAFNVSVTTGILITVIILTAYVIT--GGFFAVVWTD 184 + + A FA+ K F V + +I VI L V T GG AV+WTD Sbjct: 124 FVFTRLLAEGVRLFASAIPIKLLLDEFGVHASYRAIIIVITLITVVYTYLGGIKAVIWTD 183 Query: 185 VVQAMFMLLTLIIMPILALVEIGG------LDRATQIIASVDPNKLHPFGGATGWAAIVF 238 +Q + L ++ + +GG LD + D N H + +A Sbjct: 184 AIQMVLYLGGAVLAVAVLSAHVGGDGYARALDAGKFQLFDTDFNLAHIL--TSPFALPTA 241 Query: 239 AIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALV 298 IG A + + G ++ + + + + + SG++ T+ G L ++ Sbjct: 242 IIGGAIFAMASHGSDQLIVQRVLATRTLREGQKAMIASGVFVTVQFAAFSLVGALLWSYN 301 Query: 299 ASGS---IKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDI 355 S + + + + P +H LP V+G ++AGI+ A M + S L S++ DI Sbjct: 302 EGRSFAELGLSSSDNLYPEFILHGLPVVVSGLLVAGILGAAMGSLSSALNSMSNSTVADI 361 Query: 356 YHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILT 415 H ++ ++ ++R + A + FA + T +G +L Sbjct: 362 IHSFFRSTPSEEALLRLARWMTLVWATLMAVFACAFSASTGNVYLTGLTIAGYTYGALLG 421 Query: 416 LSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFIN 475 L + V + + + L++ ++ + G + G T+ Q + I Sbjct: 422 AFLLGRLVKRANEVDSVVAFLVTIGVMTYIVRGVKIDVTTGG--TTVSQAIAAQWLVPIG 479 Query: 476 FFVTLFIIIIVSLLTKPPED--VVKLHEE 502 +TL + ++SL + PE V L EE Sbjct: 480 VLITLLVGGVLSLFHRAPEPSAVTALDEE 508 >gb|AAK42614.1| Metabolite permease, putative [Sulfolobus solfataricus] Length = 505 Score = 82.3 bits (200), Expect = 1e-14 Identities = 103/492 (20%), Positives = 208/492 (41%), Gaps = 26/492 (5%) Query: 9 FLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFK 68 F++++ + Y +W ++ + GR++ + A ++ + + P S + Sbjct: 14 FIVFIFLGFYGAFWRKGNLDLLHEWGLAGRRLGTVLVWFLMGADLYTAYTFIAVPSSLYA 73 Query: 69 AGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAA 128 G F+A + + T A +L P+L I + +T D+++ R N+ ++ L A Sbjct: 74 KGAIYFFA-VPYVSLTFAIAMLTMPKLWIVSRNRGYVTAADFVKDRF--NSSILAALIAL 130 Query: 129 IILVFMTAYVAAQFAAGGKTFAQAFNVSVTTG-------ILITVIILTAYVITGGFFAVV 181 +V Y+A Q G K+ Q + + ++++ IIL A+ T G Sbjct: 131 TGVVAELPYIALQIV-GMKSVLQMMLLGIGNATLVSEISLIVSFIILAAFTYTSGLRGAA 189 Query: 182 WTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIG 241 T V + + + +T+I + ++ ++ GG A +I S + + + + A +++ Sbjct: 190 LTGVFKDILIWITVISVIVIVPLQYGGFTHAFSVINSANLSARYTTLPSNLQIAY-WSLF 248 Query: 242 YASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIF--ISGIWTTIVLWGAFFAGFLGFALVA 299 S + YL PH + +S +D +L I GI I+ A F G L +A+ Sbjct: 249 LGSALALYL-YPHSINGSLSADDKNRLMYSTALLPIYGIGLAII---ALF-GILVYAVPN 303 Query: 300 SGSIKVE-DPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHK 358 + S+ + +VPA+ +P W AG ++ GI + A + AS+ + R++ K Sbjct: 304 ALSVVSKYGGALVVPALITSTMPDWAAGIMLLGIFVGGLVPAAIMAIAASNLLVRNVI-K 362 Query: 359 VLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSL 418 + + K +++ + A + +A+ F P + G L P + L L Sbjct: 363 EVNPSITPKGETTLAKWISAVIKFLALAFVFLVPSTYAINLQLLGGILITQTLPAVFLGL 422 Query: 419 WWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTL-GQWFNGVPVFFINFF 477 + K A G G+IS + + + P+A + TL G + V +N Sbjct: 423 YTKWFNPWALTAGWTTGIISGTYM---FFTFGL-PRATSLYPTLFGLMYAAVIALVLNLV 478 Query: 478 VTLFIIIIVSLL 489 V++ ++ + L Sbjct: 479 VSVIGTLVANAL 490 >gb|AAA66065.1| (U08813) 597 aa protein related to Na/glucose cotransporters [Oryctolagus cuniculus] >gi|1092917|prf||2102228A Na/glucose transporter [Oryctolagus cuniculus] Length = 597 Score = 81.5 bits (198), Expect = 2e-14 Identities = 116/532 (21%), Positives = 215/532 (39%), Gaps = 68/532 (12%) Query: 11 IYLVILAYIGWWAN--KYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFK 68 +Y + +G W++ T YF+ GR + S S L +G GS Sbjct: 27 VYFALNVAVGIWSSCRASRNTVSGYFLAGRDMTWWPIGASLFGSSEGSGLFIGLAGSGAA 86 Query: 69 AGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAA 128 GL + LA + G IY +TL +Y++ R ++ LS Sbjct: 87 GGLAVAGFDWNATYVLLALAWVFGA---IYISS-EIVTLAEYIQKRF-GGQRIRMYLSVL 141 Query: 129 IILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQA 188 +L+ + ++ AG + ++T+ I Y ITGG AV++TD +Q Sbjct: 142 SLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLTITALYTITGGLVAVIYTDALQT 201 Query: 189 MFMLLTLIIMPILALVEIGGLDRATQIIASVDPNK--------------LH----PFGGA 230 + M++ +I+ I A +I G + A P++ +H P+ G Sbjct: 202 LIMVVGAVILAIKAFHQIDGYGQMEAAYARAIPSRTVANTTCHLPRADAMHMFRDPYTGD 261 Query: 231 TGWAAIVFAIG-YASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGI----WTTIVLW 285 W + F + A+W + IV R +S + + I S + +++ Sbjct: 262 LPWTGMTFGLTIMATWY--WCTDQVIVQRSLSARNLNHAKAGSILASYLKMLPMGLMIMP 319 Query: 286 G----AFFAGFLGFALVASGSIKVEDPE-----RIVPAMAIHFLPGWVAGFVIAGIISAV 336 G A F +G +V S ++ E P + + +P + G +IA ++ A+ Sbjct: 320 GMISRALFPDEVG-CVVPSECLRACGAEIGCSNIAYPKLVMELMPVGLRGLMIAVMMPAL 378 Query: 337 MSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAM-WFAIT----- 390 MS+ S +S+ DI+ + L +++++ + R+V+ + V++ W + Sbjct: 379 MSSLSSIFNSSSTLFTMDIWRR-LRPCASERELLLVGRLVIVVLIGVSVAWIPVLQGSNG 437 Query: 391 GPKVIYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGL---ISEVILEAKIY 447 G IY T+ LA + TL ++W+R ++ G+ GL + ++LE Sbjct: 438 GQLFIYMQSVTS--SLAPPVTAVFTLGIFWQRANEQGAFWGLLAGLAVGATRLVLE---- 491 Query: 448 GWAFNPKAP-GFFGTLGQWFNGVPVFFINFFVTLFII-----IIVSLLTKPP 493 +P P G T + + +++F V LF++ + SLLT PP Sbjct: 492 --FLHPAPPCGAADTRPAVLS--QLHYLHFAVALFVLTGAVAVGGSLLTPPP 539 >pir||A82432 sodium/solute symporter VCA0667 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9658084|gb|AAF96568.1| (AE004396) sodium/solute symporter [Vibrio cholerae] Length = 513 Score = 81.1 bits (197), Expect = 3e-14 Identities = 89/472 (18%), Positives = 192/472 (39%), Gaps = 36/472 (7%) Query: 11 IYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAG 70 IYL++ I W+ N+ + + GGR+ A +S A+ S +G PG +++G Sbjct: 12 IYLILTILISWFVNQRSIGNTDFSTGGRQFGWFTAGVSILATYISAMTFIGMPGWVYQSG 71 Query: 71 LGAFWAGIG---CLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSA 127 + A + +F + ++ + R+ ++ +YLE R + I + Sbjct: 72 MEALNIHLNYPIVIFFAVVFFIPVFYRMGF-------TSIYEYLEHRFGVYARTINSVVF 124 Query: 128 AIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQ 187 ++ + + A Q +S+ I+ + Y GG V+WTD++Q Sbjct: 125 ILVQCISSGVILYAIAL---ILIQILPISIVEAIVYITLFTACYTYAGGISTVIWTDMLQ 181 Query: 188 AMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIV 247 + ++ + + +L L+++ G+ ++ ++ + T WA +V A+ + V Sbjct: 182 SAVLIAGSVAIFVLLLLQVDGVHGVSREQLNIINLQFDLGVDTTLWAGVV-AVSFLHMSV 240 Query: 248 GYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFALVASGSIKVED 307 G ++ + K + + + G +GAFF F L SI ++ Sbjct: 241 --YGTNQLIIQRTLATRCEKTAQKSMLLCG-------YGAFFIYFFFALLGVLLSIFYQE 291 Query: 308 -----PERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQ 362 ++ H WV G +I+ + +A MST DS ++ D+Y + + + Sbjct: 292 RHFTNSNEVILDFVFHHTNPWVIGLIISALAAAAMSTLDSTYNSMATVATFDLYQRFIRR 351 Query: 363 ELGKKQMVNISR---IVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPILTLSLW 419 ++R +V A + ++ A++ V+ + + + + G + L L+ Sbjct: 352 NAPDHHYQAVARKMSLVAAGLVVIPALLAVSNESVLKTIASLTSIFVGIRLGSFV-LGLF 410 Query: 420 WKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAPGFFGTLGQWFNGVPV 471 + ++ I G + + +L A++ A+ AP GT+ +GV + Sbjct: 411 SNQANEKGVIAGSIISIAA--VLGARLMDIAWPWFAP--IGTVFFLVSGVVI 458 >pir||T28017 hypothetical protein ZK822.5 - Caenorhabditis elegans >gi|3881819|emb|CAA98070.1| (Z73898) Similarity to Salmonella sodium/proline symporter (SW:PUTP_SALTY), contains similarity to Pfam domain: PF00474 (Sodium:solute symporter family), Score=5.7, E-value=1.7e-08, N=1~cDNA EST yk398b5.3 comes from this gene~cDNA EST yk440a11.3 comes > Length = 577 Score = 79.6 bits (193), Expect = 8e-14 Identities = 90/368 (24%), Positives = 154/368 (41%), Gaps = 25/368 (6%) Query: 30 EDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYL 89 +++Y +GGR++ L LS + SG LMLG P F+ G W + + G + + Sbjct: 45 KEEYLMGGRQLPPLPVALSLLTTFLSGILMLGVPAEMFQRG-AQIW--LNFVIGVASSIV 101 Query: 90 LIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTF 149 L ++ K ++ L +Y R N+ LIR L + + L+F Y++ A Sbjct: 102 TCFVFLPVFH-KMKSTCLHEYFIHRY--NSILIRRLFSLLFLLFTIVYMSVVLYAPSVAL 158 Query: 150 AQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFML--LTLIIMPILALVEIG 207 + ++ +LI T Y GG AVVWTD +QA+ M + +I L+ +G Sbjct: 159 SPVLQINKWYLVLIFGCTTTLYTCLGGLKAVVWTDSLQAVIMYTGVFTLIYKGLSHPRVG 218 Query: 208 GLDRATQIIASVDPNKLHPFGGATGWAA-------IVFAIGYASWIVGYLGQPHIVTRYM 260 GL+R I + D ++ G W I G W+ + + RY Sbjct: 219 GLERVLSI--AWDSGRISEL-GRMDWRIDQYNSLWINLFSGTIVWLASFGVNQLAIQRYA 275 Query: 261 SVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFAL------VASGSIKVEDPERIVPA 314 S+ + + I+ +T + A F GF+ A + +G +K D I A Sbjct: 276 SLPSLKVAQSIIIYTLAPFTVLCSIVA-FVGFIALAYFYNCNPLETGEVKESDHITISFA 334 Query: 315 MAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISR 374 I + G ++ I+SA +ST S + ++AI D L ++ +++ Sbjct: 335 RDILQPTPGLFGLYVSCIMSATLSTLSSGMNSMAAAIYEDFLKNSLDGKITDTGATRLNK 394 Query: 375 IVVAAVAL 382 I+V L Sbjct: 395 IIVLICGL 402 >pir||T32478 hypothetical protein F52H2.4 - Caenorhabditis elegans >gi|2435612|gb|AAB71314.1| (AF026214) F52H2.4 gene product [Caenorhabditis elegans] Length = 466 Score = 78.0 bits (189), Expect = 2e-13 Identities = 90/397 (22%), Positives = 165/397 (40%), Gaps = 40/397 (10%) Query: 101 KFRAITLPDYLEARLKDNTKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTG 160 + + T+ +Y E R R ++ ++ V M Y + A A N+ +T Sbjct: 26 RLKLTTIYEYFERRFDYKC---RFVTTSLFCVQMILYNSVALYAPSLAIASITNIPITVS 82 Query: 161 ILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIAS-- 218 ILIT ++ Y+ GG A + T +Q + + LT+ + ++L E+ D T ++ Sbjct: 83 ILITAVLSAFYISVGGVKAGIHTSAIQMLLIFLTMTFIISISLREMSIHDVYTSVVHGKR 142 Query: 219 --VDPNKLHPFG----GATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPG 272 ++P H G TG +FA S + RYM++ D K + Sbjct: 143 FRINPTIRHSVWSLLIGGTGNILALFAANQLS-----------IQRYMAM-DTLKSAQKV 190 Query: 273 IFISGIWTTIVLWGAFFAGFLGFALVASGSIKVEDPERIVPAMAIHF---LPGWVAGFVI 329 + ++ + TI+L GFL +A ++ + ++P + PG V G Sbjct: 191 VLLNIVCNTIILVSYVSVGFLIYAHYKDCHPQIGNANELLPRFVMDVTSKYPGSV-GLFA 249 Query: 330 AGIISAVMSTADSQLLVASSAIARDIYHKVLGQE-----LGKKQMVNISRIVVAAVALVA 384 A + SA +ST + SS + D++ KV + L Q+ N RI+ ++ ++ Sbjct: 250 AAVYSAGISTLSASFTAVSSIVINDVW-KVYRERRKMAPLRNDQVQNAMRILPIVLSFIS 308 Query: 385 MWFAITGPKVIYQMVATAWGGLAVGFGPIL---TLSLWWKRVTKEAGIVGMAYGLISEVI 441 ++ A + ++ ++ G GP+L + L+ RV ++A +V GLI +I Sbjct: 309 IFVAFLCSMLQSIILQVSFIVFGAGGGPVLGSFVVGLFVPRVKEKAALV----GLIGSII 364 Query: 442 LEAKIYGWAFNPKAPGFFGTLGQWFNGVPVFFINFFV 478 + I + K LGQ N +F F+ Sbjct: 365 VCFSISIGSVLVKVKPVALELGQCSNQTLTYFDESFI 401 >emb|CAB88444.1| (AL353815) putative sodium-coupled permease [Streptomyces coelicolor A3(2)] Length = 527 Score = 76.1 bits (184), Expect = 1e-12 Identities = 102/476 (21%), Positives = 188/476 (39%), Gaps = 42/476 (8%) Query: 1 MNFGILFGFLIYLVILAYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLML 60 +++ +L G Y ++ IG W++K +F G K+ + +S S +S + Sbjct: 4 LDWSVLIG---YFAVMVAIGVWSHKRVDDVSDFFTAGGKMPWWLSGISHHMSGYSAVMFT 60 Query: 61 GYPGSAFKAGLGAF--WAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDN 118 GY G A+ G+ +F W+ G L PR+ + + +YL+ R Sbjct: 61 GYAGIAYTYGVTSFVTWS-FPIALGVAIGSKLFAPRINRLRSRLHVASPLEYLKNRYNLP 119 Query: 119 TKLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFF 178 T+ S ++ + VAA++AA + +++ GILIT +I Y GG + Sbjct: 120 TQQALAWSGMLLKI---VDVAAKWAAIATLLSVFTGITLNQGILITGVITGIYCTIGGLW 176 Query: 179 AVVWTDVVQAMFMLLTLIIMPILALVEIG------GLDRATQIIASVDPNKLHPFGGATG 232 A T++ Q + LL + M + ++++G G+ + P + P+G T Sbjct: 177 ADALTELGQFIIQLLAGVAMFVAVVMKLGDHGGFFGVWDEPALQGHGKP-LVGPYG--TV 233 Query: 233 WAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGA--FFA 290 + I + G L Q RYM+ + R+ R + +W ++W FF Sbjct: 234 FLLAFLFIKLFEYNGGMLNQAQ---RYMATANAREATRGARLSAVLW---LVWPLVLFFP 287 Query: 291 GFLGFALVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSA 350 ++ LV S D + M LP + G VI G S M+ S ++ Sbjct: 288 MWMSPLLVESQKADGSDSYAL---MTEQLLPHGLLGLVIVGFFSHTMAMCSSDANAIAAV 344 Query: 351 IARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGP----------KVIYQMVA 400 RD+ + + G Q + + V + + A+ V+ + VA Sbjct: 345 FTRDVAPVLSKRARGWGQRSGLLAARLTTVIFLGLSMAVATQVDSPTFKDIITVVIKWVA 404 Query: 401 TAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNPKAP 456 G +A+ +L L ++R A + GL++ ++ I W+ + P Sbjct: 405 GLMGPIAIPM--MLGLLRPFRRSGPTAALTSWGLGLVAFWLVNYPI-NWSVDGGVP 457 >gb|AAB39701.1| (U72716) unknown [Drosophila melanogaster] >gi|7302091|gb|AAF57192.1| (AE003779) CG2187 gene product [Drosophila melanogaster] Length = 623 Score = 74.9 bits (181), Expect = 2e-12 Identities = 96/383 (25%), Positives = 167/383 (43%), Gaps = 53/383 (13%) Query: 1 MNFGIL--FGFLIYLVILAYIGWWANKYTK---TEDQYFVGGRKVHVLAATLSDKASDFS 55 + FG+ F F+I L A IG + ++K T ++Y GG+K+ L +S AS S Sbjct: 22 LRFGLTDYFVFVIMLGASAGIGVYFGFFSKSKNTTEEYLRGGKKMQTLPIAISLVASQLS 81 Query: 56 GWLMLGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLP---DYLE 112 G ++ P ++ G +F LA ++I + I F + +YLE Sbjct: 82 GIAIMSIPAESYTYGFNY-------IFVVLAMLVVIPILIYIIVPVFYENNVSNCYEYLE 134 Query: 113 ARLKDNTK-LIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAY 171 R T+ L+ + + Y+ A FAQ +++ ++ I Y Sbjct: 135 MRFNKRTRQLVTFFFVTNSFLMLPVYMFIPSLA----FAQVTGMNIHLINVMVSSICIFY 190 Query: 172 VITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGG----LDRAT-----QIIASVDPN 222 + GG AVVWTDVVQ MLL+++ + +L + GG ++RA+ +DP Sbjct: 191 TMLGGIKAVVWTDVVQGAIMLLSVVAVGVLGTIRSGGMFTVMERASDGGRFNFDFGLDPR 250 Query: 223 KLHPFGGATGWAAIVFAIGYASWIVGYLG-QPHIVTRYMSVEDPRKLRRPGIFISGIWTT 281 F GAT +G G++G V R +S+ ++ + +SG+ Sbjct: 251 IRMTFWGAT--------MGGIFMWTGHIGLNQSCVQRIVSLPSYSHAKK-SLIVSGLGFL 301 Query: 282 IVLWGAFFAGFLGFA-------LVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGI-I 333 I+ + +G + FA ++A V P++++P + + G +AG + G+ I Sbjct: 302 IISFFNTISGIIMFARYYGCDPMLAG---LVSKPDKMMP-FFVQDIMGHLAG--MPGVFI 355 Query: 334 SAVMSTADSQLLVASSAIARDIY 356 S V S A S L +++A +Y Sbjct: 356 SCVFSAALSSLSATLNSLAGVVY 378 >gb|AAF57191.1| (AE003779) CG2196 gene product [Drosophila melanogaster] Length = 626 Score = 73.7 bits (178), Expect = 5e-12 Identities = 93/444 (20%), Positives = 188/444 (41%), Gaps = 45/444 (10%) Query: 18 YIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAG 77 Y G+++ K T ++Y GG+++ L +S +S SG M+ P + G Sbjct: 46 YFGFFS-KAKNTTEEYLQGGKRMPTLPVAISLVSSQLSGVAMMSVPAETYSFGFNM---- 100 Query: 78 IGCLFGTLADYLLIGPRLRIYAGKF---RAITLPDYLEARLKDNTK-LIRILSAAIILVF 133 +F A L + + I F +YLE R T+ L+ I + Sbjct: 101 ---IFVVWAMVLSVPVLIYIIVPVFYDNNVSNCYEYLELRFSKRTRQLVTITFILNQFLM 157 Query: 134 MTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLL 193 + Y+ A + +N+ + ++ ++ + Y + GG AVVWTDVVQ ML+ Sbjct: 158 LPVYMFVPSLAFSQV--TGYNIHLINTVVSSICVF--YTMLGGIKAVVWTDVVQGSVMLI 213 Query: 194 TLIIMPILALVEIGGLDRATQIIAS---VDPNKLHPFGGATGWAAIVFAIGYASWIVGYL 250 +++++ IL GG+ + A D +++ F G + F G AS ++ + Sbjct: 214 SVVLVAILGTSNTGGITNVLENAAEGGRFDFRQVNGF-GIDPRLRLTFISGMASGLLMWT 272 Query: 251 GQ----PHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFAL------VAS 300 G+ V R +S+ +R + ++G+ +++ F G + FA + + Sbjct: 273 GKLGLDQSCVQRIVSLPSYGHAKR-CLLMAGVGFLLIMSFTCFTGIIMFAYYYGCDPIQA 331 Query: 301 GSIKVEDPERIVPAMAIHFLPGWVAGFVIAGI-ISAVMSTADSQLLVASSAIARDIYHKV 359 G V P++++P I + G + G + G+ IS V S + S L + ++ A +Y Sbjct: 332 G--LVSKPDKLMP-FFIQDIMGHMMG--MPGVFISCVFSASLSSLSASLNSFAGVVYFDY 386 Query: 360 LGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIY---QMVATAWGGLAVGFGPIL-- 414 + + + + + + V + A + I G ++ ++ T W + G ++ Sbjct: 387 IKPRINHSEAKANATMKLVIVVMGA--YCIVGGFIVQNFNSIIQTMWTITGINMGAVVGV 444 Query: 415 -TLSLWWKRVTKEAGIVGMAYGLI 437 L ++ R + + G+A+ + Sbjct: 445 FCLGMFVPRCNAKVAVSGIAFSCL 468 >gb|AAC12270.1| (AF026554) sodium-dependent multi-vitamin transporter [Rattus norvegicus] >gi|3746793|gb|AAC64060.1| (AF081204) sodium dependent multivitamin transporter [Rattus norvegicus] >gi|3746795|gb|AAC64061.1| (AF081205) sodium dependent multivitamin transporter [Rattus norvegicus] Length = 634 Score = 71.8 bits (173), Expect = 2e-11 Identities = 96/455 (21%), Positives = 170/455 (37%), Gaps = 43/455 (9%) Query: 5 ILFGFLIYLVIL-----AYIGWWANKYTKTEDQYFVGGRKVHVLAATLSDKASDFSGWLM 59 ++FG L+ L ++ A GW + T + + RK+ L LS A+ S + Sbjct: 29 VVFGLLLVLSLVIGLYHACRGWGRH----TVGELLMADRKMGCLPVALSLLATFQSAVAI 84 Query: 60 LGYPGSAFKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNT 119 LG P ++ G ++ G G L + P + + +YLE R Sbjct: 85 LGGPAEIYRFGTQYWFLGCSYFLGLLIPAHIFIPVFY----RLHLTSAYEYLELRFN--- 137 Query: 120 KLIRILSAAIILVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGFFA 179 K +RI + M Y+ A + +L I+ Y GG A Sbjct: 138 KAVRICGTVTFIFQMVVYMGVALYAPSLALNAVTGFDLWLSVLALGIVCNIYTALGGLKA 197 Query: 180 VVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIA--------SVDPNKLHPFGGAT 231 V+WTDV Q + M L +++ I+ ++GGL + + +DP+ PF T Sbjct: 198 VIWTDVFQTLIMFLGQLVVIIVGAAKVGGLGHVWAVASQHGLISGIELDPD---PFVRHT 254 Query: 232 GWAAIVFAIGYASWIVGYLGQPHI-VTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFA 290 W A G ++ G V RY+S K + + L + Sbjct: 255 FW---TLAFGGVFMMLSLYGVNQAQVQRYLS-SHSEKAAVLSCYAVFPCQQVALCMSCLI 310 Query: 291 GFLGFALVASGSIKVEDPERIVPAMAIHF-------LPGWVAGFVIAGIISAVMSTADSQ 343 G + FA S+ + + + ++F +PG + G +A + S +ST S Sbjct: 311 GLVMFAYYKKYSMSPQQEQAAPDQLVLYFVMDLLKDMPG-LPGLFVACLFSGSLSTISSA 369 Query: 344 LLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKV--IYQMVAT 401 ++ D+ Q L + + + +SR + A LV + A + + Q + Sbjct: 370 FNSLATVTMEDLIQPWFPQ-LTETRAIMLSRSLAFAYGLVCLGMAYVSSHLGSVLQAALS 428 Query: 402 AWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGL 436 +G + + L +++ IVG+ GL Sbjct: 429 IFGMVGGPLLGLFCLGMFFPCANPLGAIVGLLTGL 463 >gb|AAF52616.1| (AE003620) CG8451 gene product [Drosophila melanogaster] Length = 568 Score = 71.8 bits (173), Expect = 2e-11 Identities = 108/447 (24%), Positives = 186/447 (41%), Gaps = 63/447 (14%) Query: 32 QYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSAFKAGLGAFWAGIGCLF-GTLADYLL 90 +Y +G R + V +S AS SG +LG + G ++ I + G Y+ Sbjct: 64 EYLLGSRNLKVFPVAMSLIASYISGVTILGTTSEIYNYGTQYWFIAIAIMLQGIAVSYVY 123 Query: 91 IGPRLRIYAGKFRAITLPDYLEARLKDNTKLIR----ILSAAIILVFMTAYVAAQFAAGG 146 I + G +YLE R + I IL + L F+ YV A Sbjct: 124 IPVFSALQVGSSY-----EYLEMRFHSVVRSIASFMFILDEILFLPFIV-YVPAI----- 172 Query: 147 KTFAQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEI 206 Q +++ ++ V++ Y GG AVV TD Q + M L+++ + ILA V Sbjct: 173 -ALNQVSGINLHVIAVVIVVVCVFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILATVYA 231 Query: 207 GGL----DRATQ----IIASVDPNKLHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTR 258 GL D A + I + +P+ P+ T W+ ++ G++ W +V R Sbjct: 232 NGLNVLFDDAAKGGRLIFNNTNPS---PYVRHTVWSVLIG--GFSYWTSFNAVNQTMVQR 286 Query: 259 YMSVEDPRKLRRP-GIFISGIWTTIVLWGAFFAGFLGFAL------VASGSIKVEDPERI 311 YMS+ +K R IF G+ + + + G L + + +++G I +D ++ Sbjct: 287 YMSLPSLKKARASMAIFTIGVAAFVSV--CCYVGLLIYEMYKDCDPLSAGLITHDD--QL 342 Query: 312 VPAMAIHFLPG--WVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQELGKKQM 369 +P + + ++G IAGI A +S+ L S I DI + ++ Sbjct: 343 LPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVRGCFKMQPSER-- 400 Query: 370 VNISRIVVAAVALVAMWFAITGPKVIYQM-----VATAWGGLAVG--FGPILTLSLWWKR 422 S I+V + +V + A++ V+ Q+ + T+ +A G FG + TL + Sbjct: 401 --ASTILVKSTVIVLGFVALSLVFVLEQLSGILSICTSMTAIAAGTTFG-LFTLGM---- 453 Query: 423 VTKEAGIVGMAYGLISEVILEAKIYGW 449 + A VG A G I+ +L GW Sbjct: 454 LVPWANTVGTAVGGIASALLA----GW 476 >gb|AAK42292.1| Metabolite permease, putative [Sulfolobus solfataricus] Length = 526 Score = 71.0 bits (171), Expect = 3e-11 Identities = 113/507 (22%), Positives = 202/507 (39%), Gaps = 52/507 (10%) Query: 9 FLIYLVILAYIGWWANKYTKTE----DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 F+I VI ++G++ +++ + + ++ + GR++ A ++ + + P Sbjct: 14 FIILFVIFVFLGFYGSRWRRGDLSKLHEWALAGRRLGPYLMWFLLTADLYTAYTFIAVPS 73 Query: 65 SAFKAGLGAFWAGIGCLFGTLADY--LLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLI 122 +G F+A + + + LL PRL A +T D+++ R N++++ Sbjct: 74 LVLASGPVGFFAAF---YSAVTPFIALLFMPRLWTIAKNRGYVTAADFIKDRF--NSRIL 128 Query: 123 RILSAAIILVFMTAYVAAQFAA------------GGKTFAQAFNVSVTTGILITVIILTA 170 L A +V Y+A Q G A ++S +L+ IIL A Sbjct: 129 AGLVAITGVVAELPYIALQIVGMQVALLILLLGLGVSNITLASDLS----LLVAFIILAA 184 Query: 171 YVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRA--------TQI-IASVDP 221 +V T G T V + + +L T+I + I + GG A +QI +A + Sbjct: 185 FVFTSGLRGAALTAVYKDIIILGTIISIAIYVPLAFGGFSGAFHNAQTLSSQINLALNNV 244 Query: 222 NK-----LHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFIS 276 NK P A A I AIG A + Y PH V +S D +K + + + Sbjct: 245 NKPIFYNYLPNTLAARTAYISLAIGSAFALYLY---PHAVNASVS-SDSKKSLKLSLALQ 300 Query: 277 GIWTTIVLWGAFFAGFLGFA--LVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIIS 334 ++ I+ A F G L +A V + K VPA+ + +P W G + GI Sbjct: 301 PFYSIILAVIALF-GILVYANSKVVNFIAKTHSGAVAVPALIGYSMPDWFVGIALLGIFI 359 Query: 335 AVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKV 394 + A + A++ + R+I K + +++ + A +A+ P Sbjct: 360 GGLVPAAIMAIGAANLLTRNII-KEFKPNMSPSTESALAKWISTAFKFLALALVFATPST 418 Query: 395 IYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNP- 453 + G + + P + L L+ ++ A + G A G+ S + L + F P Sbjct: 419 YAIQLQLLGGIIILQTLPSVFLGLYTSKLNGYALVGGWAGGMFSGIYL--TLLANHFGPL 476 Query: 454 KAPGFFGTLGQWFNGVPVFFINFFVTL 480 K F LG + GV IN + L Sbjct: 477 KTSSFITPLGPMYIGVLSTLINLAIGL 503 >pir||S74025 conserved hypothetical protein c0207 - Sulfolobus solfataricus >gi|1707719|emb|CAA69485.1| (Y08256) orf c02007 [Sulfolobus solfataricus] Length = 526 Score = 71.0 bits (171), Expect = 3e-11 Identities = 113/507 (22%), Positives = 202/507 (39%), Gaps = 52/507 (10%) Query: 9 FLIYLVILAYIGWWANKYTKTE----DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPG 64 F+I VI ++G++ +++ + + ++ + GR++ A ++ + + P Sbjct: 14 FIILFVIFVFLGFYGSRWRRGDLSKLHEWALAGRRLGPYLMWFLLTADLYTAYTFIAVPS 73 Query: 65 SAFKAGLGAFWAGIGCLFGTLADY--LLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLI 122 +G F+A + + + LL PRL A +T D+++ R N++++ Sbjct: 74 LVLASGPVGFFAAF---YSAVTPFIALLFMPRLWTIAKNRGYVTAADFIKDRF--NSRIL 128 Query: 123 RILSAAIILVFMTAYVAAQFAA------------GGKTFAQAFNVSVTTGILITVIILTA 170 L A +V Y+A Q G A ++S +L+ IIL A Sbjct: 129 AGLVAITGVVAELPYIALQIVGMQVALLILLLGLGVSNITLASDLS----LLVAFIILAA 184 Query: 171 YVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRA--------TQI-IASVDP 221 +V T G T V + + +L T+I + I + GG A +QI +A + Sbjct: 185 FVFTSGLRGAALTAVYKDIIILGTIISIAIYVPLAFGGFSGAFHNAQTLSSQINLALNNV 244 Query: 222 NK-----LHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFIS 276 NK P A A I AIG A + Y PH V +S D +K + + + Sbjct: 245 NKPIFYNYLPNTLAARTAYISLAIGSAFALYLY---PHAVNASVS-SDSKKSLKLSLALQ 300 Query: 277 GIWTTIVLWGAFFAGFLGFA--LVASGSIKVEDPERIVPAMAIHFLPGWVAGFVIAGIIS 334 ++ I+ A F G L +A V + K VPA+ + +P W G + GI Sbjct: 301 PFYSIILAVIALF-GILVYANSKVVNFIAKTHSGAVAVPALIGYSMPDWFVGIALLGIFI 359 Query: 335 AVMSTADSQLLVASSAIARDIYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKV 394 + A + A++ + R+I K + +++ + A +A+ P Sbjct: 360 GGLVPAAIMAIGAANLLTRNII-KEFKPNMSPSTESALAKWISTAFKFLALALVFATPST 418 Query: 395 IYQMVATAWGGLAVGFGPILTLSLWWKRVTKEAGIVGMAYGLISEVILEAKIYGWAFNP- 453 + G + + P + L L+ ++ A + G A G+ S + L + F P Sbjct: 419 YAIQLQLLGGIIILQTLPSVFLGLYTSKLNGYALVGGWAGGMFSGIYL--TLLANHFGPL 476 Query: 454 KAPGFFGTLGQWFNGVPVFFINFFVTL 480 K F LG + GV IN + L Sbjct: 477 KTSSFITPLGPMYIGVLSTLINLAIGL 503 >emb|CAC11445.1| (AL445063) conserved hypothetical membrane protein [Thermoplasma acidophilum] Length = 495 Score = 71.0 bits (171), Expect = 3e-11 Identities = 97/505 (19%), Positives = 196/505 (38%), Gaps = 33/505 (6%) Query: 11 IYLVILAYIGWWANKYTKTE----DQYFVGGRKVHVLAATLSDKASDFSGWLMLGYPGSA 66 ++ V+ IG+ A + + ++ +GGR++ A ++ + + P S Sbjct: 1 MFFVLFVLIGFLAKNFRRGNLNQLPEWALGGRRLGTFLVWFLVGADLYTAYTFIAVPSSM 60 Query: 67 FKAGLGAFWAGIGCLFGTLADYLLIGPRLRIYAGKFRAITLPDYLEARLKDNTKLIRILS 126 + G F+A + + A ++ P+L + K +T D++ R N + I Sbjct: 61 YAVGSIYFFA-VPYVSLAFAIAMITMPKLWTLSKKRGYVTAGDFVSDRFNSNALAMIIAL 119 Query: 127 AAII---------LVFMTAYVAAQFAAGGKTFAQAFNVSVTTGILITVIILTAYVITGGF 177 I+ +V M A + G A N++ +++ +++L + T G Sbjct: 120 TGIVAELPYIALQIVGMRAILTGMLTPLGGNVDLASNIA----LVLAILVLIGFTYTSGL 175 Query: 178 FAVVWTDVVQAMFMLLTLIIMPILALVEIGGLDRATQIIASVDPNKLHPFGGATGWAAIV 237 T V++ + T+I++ + V + V + F A W + Sbjct: 176 RGTSLTAVMKDAIIFTTVIVVIVTVFVAYHSALHEAFTVKPVYADLPPKFYNAY-WTLFL 234 Query: 238 FAIGYASWIVGYLGQPHIVTRYMSVEDPRKLRRPGIFISGIWTTIVLWGAFFAGFLGFAL 297 + YL PH + +S +KLR + I+ + + A F + Sbjct: 235 MSAAAL-----YL-YPHAINGSLSSMSAQKLRLSTALLP-IYGIGLAFLALFGVIIYGVP 287 Query: 298 VASGSIKV---EDPERIVPAMAIHFLPGWVAGFVIAGIISAVMSTADSQLLVASSAIARD 354 A +K+ + +VP + P W GF GI + A + ++ + R+ Sbjct: 288 AAEHVLKITYANNGAMVVPTLIATVTPSWFTGFAFLGIFIGGLVPAAIMSMSQATLLTRN 347 Query: 355 IYHKVLGQELGKKQMVNISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPIL 414 + K LG+EL +K+ I+++ + L+A+ F P+ + G + + P + Sbjct: 348 VI-KYLGRELEEKRETFIAKVSMIFFQLLALAFVFIVPETYSISLQLIGGIIILQTLPAV 406 Query: 415 TLSLWWKRVTKEAGIVGMAYGLISEVILEAK---IYGWAFNPKAPGFFGTLGQWFNGVPV 471 L ++ KR+ K A G G+++ + E +Y K +LG F G Sbjct: 407 FLGMYVKRLEKYAVAAGWLAGIVAGIYFEVYSNFVYFKYSIIKTTLMPSSLGFIFVGFTA 466 Query: 472 FFINFFVTLFIIIIVSLLTKPPEDV 496 IN V + +V L + P+++ Sbjct: 467 LVINLIVVGVVEAVVYALHRQPKNL 491 >gb|AAF46260.1| (AE003440) CG9657 gene product [Drosophila melanogaster] Length = 653 Score = 69.5 bits (167), Expect = 9e-11 Identities = 73/283 (25%), Positives = 121/283 (41%), Gaps = 31/283 (10%) Query: 150 AQAFNVSVTTGILITVIILTAYVITGGFFAVVWTDVVQAMFMLLTLIIMPILALVEIGG- 208 A N+ + T I+ V I Y GG AVVWTDV+Q + M + ++ I ++IGG Sbjct: 177 ATGVNIHIVTPIVCVVCIF--YTCIGGLKAVVWTDVIQTLIMFGAMALVLIKGTLDIGGP 234 Query: 209 ---LDRATQIIASVDPNKLHPFGGATGWAAIVFAIGYASWIVGYLGQPHIVTRYMSVEDP 265 +A + PN + ++V G A W+ +++ RY+S+ Sbjct: 235 GVVWQKAQETARLEVPNFSADLSERYTFYSLVLG-GVAHWLKSNAISQNMIQRYLSLPTL 293 Query: 266 RKLRRPGIFISGIWTTI--VLWGAFFAGFLGFALVASGS-------IKVEDPERIVPAMA 316 R R IWT I VL G+ G + A+ S + ++++P + Sbjct: 294 RDAR------IAIWTFIAGVLAFLMICGYTGLLIYATYSQCDPLETKLAQRNDQLLPLLV 347 Query: 317 IHFL---PGWVAGFVIAGIISAVMSTADSQLLVASSAIARDIYHKVLGQEL--GKKQMVN 371 + L PG + G +AG+ SA +S+ + L S+ + D L G+ V Sbjct: 348 MDTLGSYPG-LPGVFVAGVFSAALSSLSTGLNSLSAVVLEDFVKTFRKSPLTEGQTAFVM 406 Query: 372 ISRIVVAAVALVAMWFAITGPKVIYQMVATAWGGLAVGFGPIL 414 S +VV + VA+ FA+ + Q+ T +V GP+L Sbjct: 407 RSVVVVFGIIFVALVFAVEKLGAVLQLTITL---SSVANGPLL 446 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.328 0.143 0.442 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 194141123 Number of Sequences: 2977 Number of extensions: 8097242 Number of successful extensions: 29718 Number of sequences better than 1.0e-10: 116 Number of HSP's better than 0.0 without gapping: 53 Number of HSP's successfully gapped in prelim test: 63 Number of HSP's that attempted gapping in prelim test: 29297 Number of HSP's gapped (non-prelim): 133 length of query: 537 length of database: 189,106,746 effective HSP length: 52 effective length of query: 485 effective length of database: 157,985,422 effective search space: 76622929670 effective search space used: 76622929670 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 40 (21.7 bits) S2: 167 (69.5 bits)