BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1864 (slyD) DE:FKBP-type peptidyl-prolyl cis-trans isomerase
(slyD)
(266 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||B75119 fkbp-type peptidyl-prolyl cis-trans isomerase (slyd)... 529 e-149
pir||A71013 probable peptidyl-prolyl cis-trans isomerase - Pyroc... 445 e-124
pir||G69016 fkbp-type peptidyl-prolyl cis-trans isomerase - Meth... 217 1e-55
pir||A64403 peptidylprolyl isomerase (EC 5.2.1.8) - Methanococcu... 160 2e-38
sp|Q58235|FKB2_METJA PUTATIVE FKBP-TYPE PEPTIDYL-PROLYL CIS-TRAN... 160 2e-38
gi|11499571 peptidyl-prolyl cis-trans isomerase (slyD) [Archaeog... 157 1e-37
pir||T46954 peptidylprolyl isomerase (EC 5.2.1.8) [validated] - ... 143 2e-33
gb|AAK41054.1| Peptidyl-prolyl cis-trans isomerase, FKBP-type ro... 139 4e-32
emb|CAB57545.1| (Y18930) rotamase, peptidyl-prolyl cis-trans iso... 139 4e-32
pir||F72748 probable fkbp-type peptidyl-prolyl cis-trans isomera... 131 1e-29
emb|CAC12140.1| (AL445066) peptidyl-prolyl cis-trans isomerase r... 125 5e-28
sp|O52980|FKBP_METTL FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERA... 111 9e-24
sp|Q57726|FKB1_METJA PUTATIVE FKBP-TYPE PEPTIDYL-PROLYL CIS-TRAN... 105 5e-22
dbj|BAA97659.1| (AB028739) FK506 binding protein [Halobacterium ... 101 1e-20
pir||H83076 probable peptidyl-prolyl cis-trans isomerase, FkbP-t... 82 7e-15
sp|P21863|FKBX_PSEFL PROBABLE FKBP-TYPE 16 KD PEPTIDYL-PROLYL CI... 79 5e-14
sp|P22563|FKBX_ECOLI FKBP-TYPE 16 KD PEPTIDYL-PROLYL CIS-TRANS I... 77 2e-13
gb|AAF19641.1|AF201388_3 (AF201388) FkbB-type peptidyl-propyl ci... 73 3e-12
sp|O83369|SLYD_TREPA FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERA... 69 5e-11
>pir||B75119 fkbp-type peptidyl-prolyl cis-trans isomerase (slyd) PAB1864 -
Pyrococcus abyssi (strain Orsay)
>gi|5458178|emb|CAB49667.1| (AJ248285) FKBP-type
peptidyl-prolyl cis-trans isomerase (slyD) [Pyrococcus
abyssi]
Length = 266
Score = 529 bits (1349), Expect = e-149
Identities = 266/266 (100%), Positives = 266/266 (100%)
Query: 1 MKVNRGDVIRINYTGRVKETGEIFDTTYEDVAKEAGIYNPKGVYGPVPIAVGAGHVIPGL 60
MKVNRGDVIRINYTGRVKETGEIFDTTYEDVAKEAGIYNPKGVYGPVPIAVGAGHVIPGL
Sbjct: 1 MKVNRGDVIRINYTGRVKETGEIFDTTYEDVAKEAGIYNPKGVYGPVPIAVGAGHVIPGL 60
Query: 61 DKRLIGLEVGKKYTIEVPPEEGFGLRDPKLIKVFTIGQFKKQGIIPFPGLEVEVTTESGR 120
DKRLIGLEVGKKYTIEVPPEEGFGLRDPKLIKVFTIGQFKKQGIIPFPGLEVEVTTESGR
Sbjct: 61 DKRLIGLEVGKKYTIEVPPEEGFGLRDPKLIKVFTIGQFKKQGIIPFPGLEVEVTTESGR 120
Query: 121 KMKGRIITVSGGRVRVDFNHPLAGKTLVYEVEIVEKIEDPIEKIKALIELRLPMIDKDKL 180
KMKGRIITVSGGRVRVDFNHPLAGKTLVYEVEIVEKIEDPIEKIKALIELRLPMIDKDKL
Sbjct: 121 KMKGRIITVSGGRVRVDFNHPLAGKTLVYEVEIVEKIEDPIEKIKALIELRLPMIDKDKL 180
Query: 181 IIEVGEKEVRVEFNDQNIDSRTLILGEILLESDIKFLGYEKVEFKPSIEELLKPKQEQEE 240
IIEVGEKEVRVEFNDQNIDSRTLILGEILLESDIKFLGYEKVEFKPSIEELLKPKQEQEE
Sbjct: 181 IIEVGEKEVRVEFNDQNIDSRTLILGEILLESDIKFLGYEKVEFKPSIEELLKPKQEQEE 240
Query: 241 QTKETKETKEESAIEKSTEENKPNEE 266
QTKETKETKEESAIEKSTEENKPNEE
Sbjct: 241 QTKETKETKEESAIEKSTEENKPNEE 266
>pir||A71013 probable peptidyl-prolyl cis-trans isomerase - Pyrococcus
horikoshii >gi|3257822|dbj|BAA30505.1| (AP000006) 257aa
long hypothetical peptidyl-prolyl cis-trans isomerase
[Pyrococcus horikoshii]
Length = 257
Score = 445 bits (1132), Expect = e-124
Identities = 214/254 (84%), Positives = 242/254 (95%), Gaps = 2/254 (0%)
Query: 1 MKVNRGDVIRINYTGRVKETGEIFDTTYEDVAKEAGIYNPKGVYGPVPIAVGAGHVIPGL 60
MKV RGDVIR++YTGRVKETG+IFDTTYE+VAKEAGIYNPKG+YGPVPI VGAGHVI GL
Sbjct: 1 MKVERGDVIRLHYTGRVKETGQIFDTTYEEVAKEAGIYNPKGIYGPVPIIVGAGHVISGL 60
Query: 61 DKRLIGLEVGKKYTIEVPPEEGFGLRDPKLIKVFTIGQFKKQGIIPFPGLEVEVTTESGR 120
DKRL+GLEVGKKYT+EVPPEEGFGLRDPKLIKVFT+GQF+KQGI+PFPGLEVEVTT++GR
Sbjct: 61 DKRLVGLEVGKKYTLEVPPEEGFGLRDPKLIKVFTMGQFRKQGIVPFPGLEVEVTTDNGR 120
Query: 121 KMKGRIITVSGGRVRVDFNHPLAGKTLVYEVEIVEKIEDPIEKIKALIELRLPMIDKDKL 180
KMKGR+ITVSGGRVRVDFNHPLAGKTL+YEVEIVEKIEDPIEKIKALIELRLPMID+DK+
Sbjct: 121 KMKGRVITVSGGRVRVDFNHPLAGKTLIYEVEIVEKIEDPIEKIKALIELRLPMIDRDKV 180
Query: 181 IIEVGEKEVRVEFNDQNIDSRTLILGEILLESDIKFLGYEKVEFKPSIEELLKPKQEQ-- 238
IIEVGEK+V+V F +Q++D +TLILGEILLESDIKFLGYEKVEFKPS+EELL+PKQE+
Sbjct: 181 IIEVGEKDVKVNFGEQDVDPKTLILGEILLESDIKFLGYEKVEFKPSVEELLRPKQEEPV 240
Query: 239 EEQTKETKETKEES 252
EE+ KE +E EE+
Sbjct: 241 EEEKKEEQEESEEA 254
>pir||G69016 fkbp-type peptidyl-prolyl cis-trans isomerase - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622228|gb|AAB85614.1| (AE000882) fkbp-type
peptidyl-prolyl cis-trans isomerase [Methanobacterium
thermoautotrophicum]
Length = 250
Score = 217 bits (546), Expect = 1e-55
Identities = 113/255 (44%), Positives = 171/255 (66%), Gaps = 14/255 (5%)
Query: 1 MKVNRGDVIRINYTGRVKETGEIFDTTYEDVAKEAGIYNPKGVYGPVPIAVGAGHVIPGL 60
M VN+GD I+I +TG+VKETGE+FDTTYE+VA+EAG+ K ++GP+P+ VG GH+I GL
Sbjct: 1 MAVNKGDFIKIEFTGKVKETGEVFDTTYEEVAREAGL-GIKKIFGPIPVVVGGGHLIKGL 59
Query: 61 DKRLIGLEVGKKYTIEVPPEEGFGLRDPKLIKVFTIGQFKKQGIIPFPGLEVEVTTESGR 120
D+ +IG+E G++ +E+ PE+ FG RDPKL+++ +G+FK+QGI P+PG+ + V
Sbjct: 60 DEAVIGMEEGEEKHVEIEPEDAFGNRDPKLVQLIPMGEFKRQGIKPYPGMTLTVEGH--- 116
Query: 121 KMKGRIITVSGGRVRVDFNHPLAGKTLVYEVEIVEKIEDPIEKIKALIELRLPM----ID 176
+GR++ VSGGRVRVDFNH LAGKTL Y++++ E I D EK+K++I+L P ID
Sbjct: 117 --EGRVLNVSGGRVRVDFNHELAGKTLEYDLKVKEIITDDAEKVKSMIQLHYPSQNMDID 174
Query: 177 KDKLIIEVGEKEVRVE----FNDQNIDSRTLILGEILLESDIKFLGYEKVEFKPSIEELL 232
K ++ IE G+ + ++ F++++ TL I + G EKVEF E+
Sbjct: 175 KTEVKIEDGKVIIHMDEMTRFDNRSYMDVTLARFRIARDIWENIEGVEKVEFADVFEKRD 234
Query: 233 KPKQEQEEQTKETKE 247
+E+EE+ ++ E
Sbjct: 235 MEAEEKEEEVEDAGE 249
>pir||A64403 peptidylprolyl isomerase (EC 5.2.1.8) - Methanococcus jannaschii
Length = 240
Score = 160 bits (400), Expect = 2e-38
Identities = 85/240 (35%), Positives = 145/240 (60%), Gaps = 13/240 (5%)
Query: 3 VNRGDVIRINYTGRVKETGEIFDTTYEDVAKEAGIYNPKGVYGPVPIAVGAGHVIPGLDK 62
V +G +++I+Y G V G++FDTT E++AK+ GIYNP +YGPV I G G V+PGLD+
Sbjct: 11 VEKGKMVKISYDGYVD--GKLFDTTNEELAKKEGIYNPAMIYGPVAIFAGEGQVLPGLDE 68
Query: 63 RLIGLEVGKKYTIEVPPEEGFGLRDPKLIKVFTIGQFKKQGIIPFPGLEVEVTTESGRKM 122
++ ++VG++ + +PPE+ FG RDP IK+ + +F K+GI P GL + + +
Sbjct: 69 AILEMDVGEEREVVLPPEKAFGKRDPSKIKLIPLSEFTKRGIKPIKGLTITID-----GI 123
Query: 123 KGRIITVSGGRVRVDFNHPLAGKTLVYEVEIVEKIEDPIEKIKALIELRLPMIDKDKLII 182
G+I++++ GRV VDFNH LAGK + Y ++I E ++D +K ++++ +P + K+ I
Sbjct: 124 PGKIVSINSGRVLVDFNHELAGKEVKYRIKIEEVVDDKKNIVKEIVKMYVPRLSDVKVTI 183
Query: 183 EVGEKEVRV-EFND--QNIDSRTLILGEILLESDIKFLGYEKVEFKPSIEELLKPKQEQE 239
G ++ + EF NI + + + +L+ + EKV F + E + K+E +
Sbjct: 184 RNGTVKIELPEFAPFIPNIQTAKMAIANEILK---RLEDAEKVSFVETFERKKETKEENK 240
>sp|Q58235|FKB2_METJA PUTATIVE FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE MJ0825
(PPIASE) (ROTAMASE) >gi|2826328|gb|AAB98824.1| (U67526)
peptidyl-prolyl cis-trans isomerase, FKBP-type rotamase
(slyD) [Methanococcus jannaschii]
Length = 231
Score = 160 bits (400), Expect = 2e-38
Identities = 85/240 (35%), Positives = 145/240 (60%), Gaps = 13/240 (5%)
Query: 3 VNRGDVIRINYTGRVKETGEIFDTTYEDVAKEAGIYNPKGVYGPVPIAVGAGHVIPGLDK 62
V +G +++I+Y G V G++FDTT E++AK+ GIYNP +YGPV I G G V+PGLD+
Sbjct: 2 VEKGKMVKISYDGYVD--GKLFDTTNEELAKKEGIYNPAMIYGPVAIFAGEGQVLPGLDE 59
Query: 63 RLIGLEVGKKYTIEVPPEEGFGLRDPKLIKVFTIGQFKKQGIIPFPGLEVEVTTESGRKM 122
++ ++VG++ + +PPE+ FG RDP IK+ + +F K+GI P GL + + +
Sbjct: 60 AILEMDVGEEREVVLPPEKAFGKRDPSKIKLIPLSEFTKRGIKPIKGLTITID-----GI 114
Query: 123 KGRIITVSGGRVRVDFNHPLAGKTLVYEVEIVEKIEDPIEKIKALIELRLPMIDKDKLII 182
G+I++++ GRV VDFNH LAGK + Y ++I E ++D +K ++++ +P + K+ I
Sbjct: 115 PGKIVSINSGRVLVDFNHELAGKEVKYRIKIEEVVDDKKNIVKEIVKMYVPRLSDVKVTI 174
Query: 183 EVGEKEVRV-EFND--QNIDSRTLILGEILLESDIKFLGYEKVEFKPSIEELLKPKQEQE 239
G ++ + EF NI + + + +L+ + EKV F + E + K+E +
Sbjct: 175 RNGTVKIELPEFAPFIPNIQTAKMAIANEILK---RLEDAEKVSFVETFERKKETKEENK 231
>gi|11499571 peptidyl-prolyl cis-trans isomerase (slyD) [Archaeoglobus fulgidus]
>gi|7450753|pir||D69498 peptidyl-prolyl cis-trans
isomerase (slyD) homolog - Archaeoglobus fulgidus
>gi|2648545|gb|AAB89261.1| (AE000965) peptidyl-prolyl
cis-trans isomerase (slyD) [Archaeoglobus fulgidus]
Length = 253
Score = 157 bits (394), Expect = 1e-37
Identities = 104/266 (39%), Positives = 155/266 (58%), Gaps = 23/266 (8%)
Query: 3 VNRGDVIRINYTGRVKETGEIFDTTYEDVAKEAGIYNPKGVYGPVPIAVGAGHVIPGLDK 62
++ GD IR++YT ++ E G I DTT E+VAKE GIYN YG + I VG GHV+PGL++
Sbjct: 2 ISDGDFIRLSYTAKL-EDGTIVDTTDEEVAKEHGIYNENARYGDIYIVVGKGHVLPGLEE 60
Query: 63 RLIGLEVGKKYTIEVPPEEGFGLRDPKLIKVFTIGQFKKQGIIPFPGLEVEVTTESGRKM 122
+ G +VG K T+E+PPE+ FG +P L F++ +FK++ P G V + G ++
Sbjct: 61 DIKGKDVGYKGTVEIPPEKAFGEYNPDLKDTFSVNRFKER---PEIGQRVRI----GDRI 113
Query: 123 KGRIITVSGGRVRVDFNHPLAGKTLVYEVEIVEKIEDPIEKIKAL------IELRLPMID 176
G + + G RV VDFNHPLAGK ++++ EI EK+E P +KIKAL I+++ I+
Sbjct: 114 -GTVERIVGRRVIVDFNHPLAGKKIIFDYEIKEKLEKPEDKIKALFVIHTGIDVKDVKIE 172
Query: 177 KDKLIIEVGEKEVRVEFNDQNIDSRTLILGEILLESDIKFLGYEKVEFKPSIEELLKPKQ 236
K I+EV V N + R + +I +++K + E VE +ELLK +
Sbjct: 173 DGKAIVEVSSD---VYLNQVFLIGRYRAVKDIFENTEVKEI--EIVERFEREQELLKLGE 227
Query: 237 E---QEEQTKETKETKEESAIEKSTE 259
E +EE KE + +EE E+ E
Sbjct: 228 EIKAEEEAEKEGESGEEEEQTEEKEE 253
>pir||T46954 peptidylprolyl isomerase (EC 5.2.1.8) [validated] - Thermococcus
sp. (strain KS-1) >gi|4126414|dbj|BAA36560.1| (AB012209)
FKBP-type PPIase [Thermococcus sp. KS-1]
Length = 159
Score = 143 bits (358), Expect = 2e-33
Identities = 72/155 (46%), Positives = 105/155 (67%), Gaps = 6/155 (3%)
Query: 1 MKVNRGDVIRINYTGRVKETGEIFDTTYEDVAKEAGIYNPKGVYGPVPIAVGAGHVIPGL 60
MKV GD + +Y GR E GE+FDT+YE++A+E GI + YGP+ + +G G +IPGL
Sbjct: 1 MKVEAGDYVLFHYVGRF-EDGEVFDTSYEEIARENGILVEEREYGPMWVRIGVGEIIPGL 59
Query: 61 DKRLIGLEVGKKYTIEVPPEEGFGLRDPKLIKVFTIGQFKKQGIIPFPGLEVEVTTESGR 120
D+ +IG+E G+K T+ VPPE+ +G+ +P+L+ +F K G+ P GL V T+SG
Sbjct: 60 DEAIIGMEAGEKKTVTVPPEKAYGMPNPELVISVPREEFTKAGLEPQEGL--YVMTDSG- 116
Query: 121 KMKGRIITVSGGRVRVDFNHPLAGKTLVYEVEIVE 155
+I++V V +DFNHPLAGKTLV+EVE++E
Sbjct: 117 --IAKIVSVGESEVSLDFNHPLAGKTLVFEVEVIE 149
>gb|AAK41054.1| Peptidyl-prolyl cis-trans isomerase, FKBP-type rotamase [Sulfolobus
solfataricus]
Length = 235
Score = 139 bits (346), Expect = 4e-32
Identities = 76/187 (40%), Positives = 115/187 (60%), Gaps = 6/187 (3%)
Query: 7 DVIRINYTGRVKETGEIFDTTYEDVAKEAGIYNPKGVYGPVPIAVGAGHVIPGLDKRLIG 66
D I I YT ++K+TGEI DTT E+ AK+A IY+ YGP + +G +I GL++ L
Sbjct: 6 DFIYIEYTAKIKDTGEIVDTTNEEEAKKANIYDETRNYGPRLVILGENRLIKGLEEALYN 65
Query: 67 LEVGKKYTIEVPPEEGFGLRDPKLIKVFTIGQFKKQGIIPFPGLEVEVTTESGRKMKGRI 126
+ ++ TIE+PPE+ +G RD IK+ +G+ ++QGI P + ++ S I
Sbjct: 66 FNLNEEKTIEIPPEKAYGERDNSKIKIVPLGELRRQGITAVPNRVLRLSDGS----LAVI 121
Query: 127 ITVSGGRVRVDFNHPLAGKTLVYEVEIVEKIEDPIEKIKALIELRLPMIDKDKLIIEV-- 184
+VSGGRV +D NHPLAG+TLVY V++V+ + + +KI ALIE R + +E+
Sbjct: 122 RSVSGGRVVLDLNHPLAGRTLVYNVKVVKVLNNAKDKIMALIERRFSSKYANGFNVELDD 181
Query: 185 GEKEVRV 191
G+K VR+
Sbjct: 182 GKKSVRI 188
>emb|CAB57545.1| (Y18930) rotamase, peptidyl-prolyl cis-trans isomerase [Sulfolobus
solfataricus]
Length = 235
Score = 139 bits (346), Expect = 4e-32
Identities = 76/187 (40%), Positives = 115/187 (60%), Gaps = 6/187 (3%)
Query: 7 DVIRINYTGRVKETGEIFDTTYEDVAKEAGIYNPKGVYGPVPIAVGAGHVIPGLDKRLIG 66
D I I YT ++K+TGEI DTT E+ AK+A IY+ YGP + +G +I GL++ L
Sbjct: 6 DFIYIEYTAKIKDTGEIVDTTNEEEAKKANIYDETRNYGPRLVILGENRLIKGLEEALYN 65
Query: 67 LEVGKKYTIEVPPEEGFGLRDPKLIKVFTIGQFKKQGIIPFPGLEVEVTTESGRKMKGRI 126
+ ++ TIE+PPE+ +G RD IK+ +G+ ++QGI P + ++ S I
Sbjct: 66 FNLNEEKTIEIPPEKAYGERDNSKIKIVPLGELRRQGITAVPNRVLRLSDGS----LAVI 121
Query: 127 ITVSGGRVRVDFNHPLAGKTLVYEVEIVEKIEDPIEKIKALIELRLPMIDKDKLIIEV-- 184
+VSGGRV +D NHPLAG+TLVY V++V+ + + +KI ALIE R + +E+
Sbjct: 122 RSVSGGRVVLDLNHPLAGRTLVYNVKVVKVLNNAKDKIMALIERRFSSKYANGFNVELDD 181
Query: 185 GEKEVRV 191
G+K VR+
Sbjct: 182 GKKSVRI 188
>pir||F72748 probable fkbp-type peptidyl-prolyl cis-trans isomerase APE0517 -
Aeropyrum pernix (strain K1) >gi|5104166|dbj|BAA79482.1|
(AP000059) 268aa long hypothetical fkbp-type
peptidyl-prolyl cis-trans isomerase [Aeropyrum pernix]
Length = 268
Score = 131 bits (325), Expect = 1e-29
Identities = 96/265 (36%), Positives = 144/265 (54%), Gaps = 16/265 (6%)
Query: 1 MKVNRGDVIRINYTGRVKETGE--IFDTTYEDVAKEAGIYNPKGVYGPVPIAVGAGHVIP 58
M + GD + INYT +V E G + DTT E+VAK++GIY+PK VY P+ VG ++
Sbjct: 2 MPLKDGDFVLINYTVKVVEDGSERVIDTTLEEVAKKSGIYDPKRVYKEFPVIVGKTSLLG 61
Query: 59 GLDKRLIGLEVGKKYTIEVPPEEGFGLRDPKLIKVFTIGQFKKQGIIPFPGLEVEVTTES 118
L+K L L+VG++ +EVPPEE FG +L+ + + ++ I G EVE
Sbjct: 62 PLEKVLKELDVGERREVEVPPEEAFGEYKKELVVRVPVKRLRRMNIPVRVGEEVEA---G 118
Query: 119 GRKMKGRIITVSGGRVRVDFNHPLAGKTLVYEVEIVEKIEDPIEKIKALIELRLPMIDKD 178
GR +G+II V+ +DFNHPLAGK L EVE+V K+ D +E ++ R +D D
Sbjct: 119 GR--RGKIIRVTERFAFIDFNHPLAGKKLKIEVEVVGKV-DSVEDKARILAARALGLDPD 175
Query: 179 KLIIEV--GEKEVRVEFNDQNIDSRTLILGEILLESDIK-FLGYEKVEFKPSIEELLKPK 235
K+ EV G KE+ ++ + + L SD++ +L KV+ SIE P+
Sbjct: 176 KIHAEVREGGKEITLKLPPEVLGLSDLDALLAKAVSDVREYLSPRKVDVVISIE---FPE 232
Query: 236 QEQEEQTKETKETKEESAIEKSTEE 260
+ +EE E +T E E +E+
Sbjct: 233 EAREE--AEASDTGEGGEAEGESEQ 255
>emb|CAC12140.1| (AL445066) peptidyl-prolyl cis-trans isomerase related protein
[Thermoplasma acidophilum]
Length = 261
Score = 125 bits (311), Expect = 5e-28
Identities = 90/275 (32%), Positives = 152/275 (54%), Gaps = 32/275 (11%)
Query: 2 KVNRGDVIRINYTGRVKETGEIFDTTYEDVAKEAGIYNPKGVYGPVPIAVGAGHVIPGLD 61
++N GD I+I + RV E ++ T+ D+AKE I++ YG + + VG + ++
Sbjct: 3 QLNDGDFIKIEFEMRVGEEKKLVSTSKADLAKENDIFDENARYGDIVVIVGQEGIFKEVN 62
Query: 62 KRLIGLEVGKKYTIEVPPEEGFGLRDPKLIKVFTIGQFKKQGIIPFPGLEVEVTTESGRK 121
+ E G++ +EVPPE+ FG R P IK+ T+ +F++ I P G EVE+ +
Sbjct: 63 EAFRKAEPGQEVEVEVPPEDAFGQRLPSNIKIHTMREFQRLNIDPQVGKEVEI-----NR 117
Query: 122 MKGRIITVSGGRVRVDFNHPLAGKTLVYEVEIVEKIEDPIEKIKALI------ELRLPMI 175
GRII+V+ GRV VD+NH AGKT+ Y+ +I I +P+EK++A+I E +
Sbjct: 118 RVGRIISVTPGRVLVDYNHRWAGKTVYYKFKINGVITEPVEKVRAIIANNYNPEGFNVTL 177
Query: 176 DKDKLIIEVGEKEVRVEFNDQNIDSRTLILGEILLESDIKFL-GYEKVEFKPSIEELLKP 234
D D + IE+ E +F+ +D++ I+ + K++ GY+ V +L+
Sbjct: 178 DSD-IKIEIPE---GAKFSLPWLDAKYNIVNTVR-----KYVPGYDIV--------ILEV 220
Query: 235 KQEQEEQTKETKETKEESA---IEKSTEENKPNEE 266
++QEEQ E ++ KEESA + T E++P ++
Sbjct: 221 YKKQEEQKAEGEQKKEESAPAEAKTETSESQPEQK 255
>sp|O52980|FKBP_METTL FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE (PPIASE) (ROTAMASE)
(MTFK) >gi|2804282|dbj|BAA24446.1| (D89881) peptidyl
prolyl cis-trans isomerase [Methanococcus
thermolithotrophicus]
Length = 154
Score = 111 bits (275), Expect = 9e-24
Identities = 57/156 (36%), Positives = 95/156 (60%), Gaps = 6/156 (3%)
Query: 3 VNRGDVIRINYTGRVKETGEIFDTTYEDVAKEAGIYNPKGVYGPVPIAVGAGHVIPGLDK 62
V++G I+++Y G++ E+G++FDT+ E+VAKEAGIY P Y P+ VG G +I G ++
Sbjct: 5 VDKGVKIKVDYIGKL-ESGDVFDTSIEEVAKEAGIYAPDREYEPLEFVVGEGQLIQGFEE 63
Query: 63 RLIGLEVGKKYTIEVPPEEGFGLRDPKLIKVFTIGQFKKQGIIPFPGLEVEVTTESGRKM 122
++ +EVG + T+++P E+ +G R+ LI+ FK+ P G+ + +
Sbjct: 64 AVLDMEVGDEKTVKIPAEKAYGNRNEMLIQKIPRDAFKEADFEPEEGMVI-----LAEGI 118
Query: 123 KGRIITVSGGRVRVDFNHPLAGKTLVYEVEIVEKIE 158
I V+ V +DFNH LAGK LV+ ++I+E +E
Sbjct: 119 PATITEVTDNEVTLDFNHELAGKDLVFTIKIIEVVE 154
>sp|Q57726|FKB1_METJA PUTATIVE FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE MJ0278
(PPIASE) (ROTAMASE) >gi|2129179|pir||G64334
peptidylprolyl isomerase (EC 5.2.1.8) - Methanococcus
jannaschii >gi|1591004|gb|AAB98266.1| (U67483)
peptidyl-prolyl cis-trans isomerase, FKBP-type rotamase
(slyD) [Methanococcus jannaschii]
Length = 157
Score = 105 bits (260), Expect = 5e-22
Identities = 56/151 (37%), Positives = 91/151 (60%), Gaps = 7/151 (4%)
Query: 3 VNRGDVIRINYTGRVKETGEIFDTTYEDVAKEAGIYNPKGVYGPVPIAVGAGHVIPGLDK 62
+ +GD ++++Y V G++ DT+ E+VAKE IY P+ Y P+ VG G +I G ++
Sbjct: 5 IKKGDYVKVDYILEVD--GKVIDTSIEEVAKENKIYYPEREYEPIGFIVGNGELIEGFEE 62
Query: 63 RLIGLEVGKKYTIEVPPEEGFGLRDPKLIKVFTIGQFKKQGIIPFPGLEVEVTTESGRKM 122
+IG+EVG++ T+ +PPE+G+GLRD +LI+ F P G+ + SG +
Sbjct: 63 AVIGMEVGEEKTVTIPPEKGYGLRDERLIQEIPKEMFADADFEPQEGM---LILASG--I 117
Query: 123 KGRIITVSGGRVRVDFNHPLAGKTLVYEVEI 153
+II V+ V +DFNH LAGK L + +++
Sbjct: 118 PAKIIKVTDDTVTLDFNHELAGKELKFTIKV 148
>dbj|BAA97659.1| (AB028739) FK506 binding protein [Halobacterium cutirubrum]
>gi|10580813|gb|AAG19641.1| (AE005052) peptidyl-prolyl
cis-trans isomerase; SlyD [Halobacterium sp. NRC-1]
Length = 303
Score = 101 bits (249), Expect = 1e-20
Identities = 58/197 (29%), Positives = 102/197 (51%), Gaps = 9/197 (4%)
Query: 6 GDVIRINYTGRVKETGEIFDTTYEDVAKEAGIYNPKGVYGPVPIAVGAGHVIPGLDKRLI 65
GD + ++YT ++ E+ DTT E++A+ G+ + + P I +G H+ ++ ++
Sbjct: 23 GDFVELSYTAYTVDSEELVDTTDEEIAESEGVDTDEQEFSPRTIVLGEEHIFAAVEDDIV 82
Query: 66 GLEVGKKYTIEVPPEEGFGLRDPKLIKVFTIGQFKKQGIIPFPGLEVEVTTESGRKMKGR 125
G VG T+ V EE FG D ++ + + + +PG V+V E G
Sbjct: 83 GQSVGDDGTVLV--EEAFGEYDEDEVRTVSANKIPEDD--RYPGAHVDVDGEHGH----- 133
Query: 126 IITVSGGRVRVDFNHPLAGKTLVYEVEIVEKIEDPIEKIKALIELRLPMIDKDKLIIEVG 185
+ + GGR RVDFNHPLAG+ + YE E++++I D ++ +E+ + L+ E
Sbjct: 134 VEAIIGGRARVDFNHPLAGEDIEYEYEVLDEITDREQQAVGFLEMMFDVELDVDLVTETV 193
Query: 186 EKEVRVEFNDQNIDSRT 202
E+EV E D + ++ T
Sbjct: 194 EEEVTEETEDGDAETTT 210
>pir||H83076 probable peptidyl-prolyl cis-trans isomerase, FkbP-type PA4558
[imported] - Pseudomonas aeruginosa (strain PAO1)
>gi|9950803|gb|AAG07946.1|AE004869_10 (AE004869)
probable peptidyl-prolyl cis-trans isomerase, FkbP-type
[Pseudomonas aeruginosa]
Length = 146
Score = 81.9 bits (199), Expect = 7e-15
Identities = 45/137 (32%), Positives = 73/137 (52%), Gaps = 16/137 (11%)
Query: 19 ETGEIFDTTYEDVAKEAGIYNPKGVYGPVPIAVGAGHVIPGLDKRLIGLEVGKKYTIEVP 78
E G + D+T++ P VG G+++PG ++ L GL+ G K T+ +
Sbjct: 22 EDGNVVDSTFDKQ--------------PASFKVGDGNLLPGFEQALFGLKAGDKRTLSIL 67
Query: 79 PEEGFGLRDPKLIKVFTIGQFKKQGIIPFPGLEVEVTTESGRKMKGRIITVSGGRVRVDF 138
PE+GFG +P+ +++ QF+ + GL V + ++ G + +V VDF
Sbjct: 68 PEQGFGQPNPQNVQIMPRDQFQDMELA--EGLLVIFNDAAKTELPGVVKAFDEQQVTVDF 125
Query: 139 NHPLAGKTLVYEVEIVE 155
NHPLAGKTL +EVEI++
Sbjct: 126 NHPLAGKTLAFEVEIID 142
>sp|P21863|FKBX_PSEFL PROBABLE FKBP-TYPE 16 KD PEPTIDYL-PROLYL CIS-TRANS ISOMERASE
(PPIASE) (ROTAMASE) >gi|94843|pir||C37152 hypothetical
protein 149 - Pseudomonas fluorescens
>gi|151349|gb|AAA25885.1| (M35366) ORF149 [Pseudomonas
fluorescens]
Length = 150
Score = 79.2 bits (192), Expect = 5e-14
Identities = 42/154 (27%), Positives = 79/154 (51%), Gaps = 17/154 (11%)
Query: 2 KVNRGDVIRINYTGRVKETGEIFDTTYEDVAKEAGIYNPKGVYGPVPIAVGAGHVIPGLD 61
++ + + +++ R+ E G+ D+T++ P VG G+++PG +
Sbjct: 10 RIGQNTEVTLHFALRL-ENGDTVDSTFDKA--------------PATFKVGDGNLLPGFE 54
Query: 62 KRLIGLEVGKKYTIEVPPEEGFGLRDPKLIKVFTIGQFKKQGIIPFPGLEVEVTTESGRK 121
L G + G K T+++ PE FG +P+ +++ QF+ + GL V + +
Sbjct: 55 AALFGFKAGDKRTLQILPENAFGQPNPQNVQIIPRSQFQNMDL--SEGLLVIFNDAANTE 112
Query: 122 MKGRIITVSGGRVRVDFNHPLAGKTLVYEVEIVE 155
+ G + +V +DFNHPLAGKTL ++VEI++
Sbjct: 113 LPGVVKAFDDAQVTIDFNHPLAGKTLTFDVEIID 146
>sp|P22563|FKBX_ECOLI FKBP-TYPE 16 KD PEPTIDYL-PROLYL CIS-TRANS ISOMERASE (PPIASE)
(ROTAMASE) >gi|95954|pir||JE0402 probable peptidylprolyl
isomerase (EC 5.2.1.8) 16K fkbP-type - Escherichia coli
>gi|41932|emb|CAA38706.1| (X54945) ORF 1 [Escherichia
coli] >gi|216455|dbj|BAA01306.1| (D10483) hypothetical
16.4K protein(PIR:JE0402) [Escherichia coli]
>gi|1786211|gb|AAC73139.1| (AE000113) probable FKBX-type
16KD peptidyl-prolyl cis-trans isomerase (a rotamase)
[Escherichia coli K12]
Length = 149
Score = 76.9 bits (186), Expect = 2e-13
Identities = 40/110 (36%), Positives = 64/110 (57%), Gaps = 1/110 (0%)
Query: 46 PVPIAVGAGHVIPGLDKRLIGLEVGKKYTIEVPPEEGFGLRDPKLIKVFTIGQFKKQGII 105
P +G + GL++ L+GL+VG K T + P+ FG+ P LI+ F+ +F G
Sbjct: 34 PALFRLGDASLSEGLEQHLLGLKVGDKTTFSLEPDAAFGVPSPDLIQYFSRREFMDAGE- 92
Query: 106 PFPGLEVEVTTESGRKMKGRIITVSGGRVRVDFNHPLAGKTLVYEVEIVE 155
P G + T G +M G I ++G + VDFNHPLAG+T+ +++E++E
Sbjct: 93 PEIGAIMLFTAMDGSEMPGVIREINGDSITVDFNHPLAGQTVHFDIEVLE 142
>gb|AAF19641.1|AF201388_3 (AF201388) FkbB-type peptidyl-propyl cis-trans isomerase
[Klebsiella pneumoniae]
Length = 149
Score = 73.0 bits (176), Expect = 3e-12
Identities = 39/110 (35%), Positives = 64/110 (57%), Gaps = 1/110 (0%)
Query: 46 PVPIAVGAGHVIPGLDKRLIGLEVGKKYTIEVPPEEGFGLRDPKLIKVFTIGQFKKQGII 105
P +G + GL+++L+GL+ G+K + P+ FG+ P LI+ F+ +F G
Sbjct: 34 PALFRLGDTSLSEGLEQQLLGLKEGEKKAFSLEPDAAFGVPSPDLIQYFSRREFIDAGE- 92
Query: 106 PFPGLEVEVTTESGRKMKGRIITVSGGRVRVDFNHPLAGKTLVYEVEIVE 155
P G + T G +M G I V+G + VDFNHPLAG+T+ +++E++E
Sbjct: 93 PEIGAIMLFTAMDGSEMPGVIREVNGDSITVDFNHPLAGRTVHFDIEVLE 142
>sp|O83369|SLYD_TREPA FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD (PPIASE)
(ROTAMASE) >gi|7521292|pir||D71336 probable
peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) -
syphilis spirochete >gi|3322625|gb|AAC65334.1|
(AE001214) peptidyl-prolyl cis-trans isomerase,
FKBP-type (slyD) [Treponema pallidum]
Length = 176
Score = 69.1 bits (166), Expect = 5e-11
Identities = 54/171 (31%), Positives = 85/171 (49%), Gaps = 23/171 (13%)
Query: 1 MKVNRGDVIRINYTGRVKETGEIFDTTYEDVAKEAGIYNPKGVYGPVPIAVGAGHVIPGL 60
MK+ V+ I YT R +TGEI D++ V G + G G +IPGL
Sbjct: 1 MKIANECVVNIEYTLR-DDTGEIIDSS--------------DVMGALEYVQGHGMIIPGL 45
Query: 61 DKRLIGLEVGKKYTIEVPPEEGFGLRDPKLIKVFTIGQFKKQGIIPFPGLEVEVTTESGR 120
+ LI E G+++++ +PP +G L T+G+ + +P +EV + ++G
Sbjct: 46 ETALINREEGEEFSVTIPPVGAYGEVQEDL--RMTVGRDQFPPNVP---IEVGMRFDAGS 100
Query: 121 KMKGRIITVS---GGRVRVDFNHPLAGKTLVYEVEIVEKIEDPIEKIKALI 168
R +TV+ G + VD NHPLAGKTL +EV + E + + AL+
Sbjct: 101 GGDSRPVTVTDVQGETIIVDGNHPLAGKTLHFEVAVRSVREATDDDLAALL 151
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.313 0.139 0.379
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 101837094
Number of Sequences: 2977
Number of extensions: 4771335
Number of successful extensions: 28945
Number of sequences better than 1.0e-10: 19
Number of HSP's better than 0.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 28904
Number of HSP's gapped (non-prelim): 21
length of query: 266
length of database: 189,106,746
effective HSP length: 58
effective length of query: 208
effective length of database: 154,394,500
effective search space: 32114056000
effective search space used: 32114056000
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 42 (21.8 bits)
S2: 164 (68.3 bits)