BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1868 (PAB1868) DE:mRNA 3'-end processing factor, putative (651 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||F75118 probable mRNA 3'-end processing factor PAB1868 - Pyr... 1303 0.0 pir||F71013 hypothetical protein PH1404 - Pyrococcus horikoshii ... 1272 0.0 sp|Q58633|YC36_METJA HYPOTHETICAL PROTEIN MJ1236 >gi|2128070|pir... 769 0.0 pir||F69027 cleavage and polyadenylation specificity factor - Me... 743 0.0 gi|11498093 mRNA 3'-end processing factor, putative [Archaeoglob... 707 0.0 gb|AAG18954.1| (AE004996) mRNA 3'-end processing factor homolog;... 631 e-180 emb|CAB57542.1| (Y18930) mRNA 3'-end polyadenylation factor [Sul... 619 e-176 gb|AAK41056.1| mRNA 3'-end processing factor, putative [Sulfolob... 619 e-176 pir||C72749 probable cleavage and polyadenylation factor subunit... 542 e-153 emb|CAC11752.1| (AL445064) conserved hypothetical protein [Therm... 481 e-134 sp|Q57626|Y162_METJA HYPOTHETICAL PROTEIN MJ0162 >gi|2129218|pir... 267 2e-70 gb|AAK40713.1| mRNA 3'-end processing factor, putative [Sulfolob... 218 2e-55 pir||G64305 hypothetical protein YLR277c homolog - Methanococcus... 214 2e-54 sp|Q60355|Y047_METJA HYPOTHETICAL PROTEIN MJ0047 >gi|2826239|gb|... 214 2e-54 gb|AAF56931.1| (AE003771) CG1972 gene product [Drosophila melano... 213 6e-54 pir||T20694 hypothetical protein F10B5.8 - Caenorhabditis elegan... 210 5e-53 gi|11498143 mRNA 3'-end processing factor, putative [Archaeoglob... 209 9e-53 pir||T37848 probable cleavage and polyadenylation specifity fact... 204 3e-51 pir||C72774 probable cleavage and polyadenylation specificity fa... 203 5e-51 emb|CAA65151.1| (X95906) Cleavage and Polyadenylation Specifity ... 202 9e-51 gi|7706427 cleavage and polyadenylation specific factor 3, 73kD ... 202 9e-51 gi|9055194 cleavage and polyadenylation specificity factor 3; 73... 201 2e-50 gb|AAD12712.1| (AC006069) putative cleavage and polyadenylation ... 201 2e-50 gb|AAF55578.1| (AE003723) CG7698 gene product [Drosophila melano... 195 1e-48 dbj|BAA33615.1| (AB012956) unknown [Vibrio cholerae] 192 1e-47 pir||F82345 conserved hypothetical protein VC0264 [imported] - V... 190 4e-47 gb|AAF27682.1|AC018908_21 (AC018908) putative cleavage and polya... 187 3e-46 gi|6323307 Ysh1p [Saccharomyces cerevisiae] >gi|1077401|pir||S51... 186 6e-46 pir||C83195 hypothetical protein PA3614 [imported] - Pseudomonas... 182 1e-44 gb|AAG20574.1| (AE005128) mRNA 3'-end processing factor homolog;... 181 2e-44 pir||G75600 cleavage and polyadenylation specificity factor-rela... 170 4e-41 emb|CAC11477.1| (AL445064) conserved hypothetical protein [Therm... 164 2e-39 pir||T18488 hypothetical protein C0825c - malaria parasite (Plas... 156 8e-37 gb|AAB70268.1| (AF017269) 73 kDA subunit of cleavage and polyade... 152 9e-36 dbj|BAB13943.1| (AK021939) unnamed protein product [Homo sapiens] 151 3e-35 gb|AAD54657.1|AF090685_1 (AF090685) hypothetical protein [Vibrio... 149 8e-35 dbj|BAB14541.1| (AK023356) unnamed protein product [Homo sapiens] 123 4e-27 emb|CAB61133.1| (AL132951) predicted using Genefinder; prelimina... 112 1e-23 gb|AAF82809.1|AF283277_1 (AF283277) polyadenylation cleavage/spe... 105 2e-21 dbj|BAB10061.1| (AB005244) cleavage and polyadenylation specific... 104 2e-21 sp|Q10568|CPSB_BOVIN CLEAVAGE AND POLYADENYLATION SPECIFICITY FA... 85 2e-15 gi|8393762 cleavage and polyadenylation specific factor 2, 100kD... 84 5e-15 gb|AAD33061.1|AF139986_1 (AF139986) cleavage and polyadenylation... 83 9e-15 gi|11423200 hypothetical protein FLJ20542 [Homo sapiens] 81 3e-14 gb|AAD46873.1|AF160933_1 (AF160933) BcDNA.LD14168 [Drosophila me... 81 5e-14 gi|8923512 hypothetical protein FLJ20542 [Homo sapiens] >gi|7020... 81 5e-14 pir||T32487 hypothetical protein F09G2.4 - Caenorhabditis elegan... 79 2e-13 dbj|BAB01576.1| (AB045994) unnamed protein product [Macaca fasci... 73 8e-12 >pir||F75118 probable mRNA 3'-end processing factor PAB1868 - Pyrococcus abyssi (strain Orsay) >gi|5458174|emb|CAB49663.1| (AJ248285) mRNA 3'-end processing factor, putative [Pyrococcus abyssi] Length = 651 Score = 1303 bits (3336), Expect = 0.0 Identities = 651/651 (100%), Positives = 651/651 (100%) Query: 1 MSALIKRETQVDQILKDIRGIVNQMVPREAKITEIEFEGPELVIYVKNPEAIMKDGELIK 60 MSALIKRETQVDQILKDIRGIVNQMVPREAKITEIEFEGPELVIYVKNPEAIMKDGELIK Sbjct: 1 MSALIKRETQVDQILKDIRGIVNQMVPREAKITEIEFEGPELVIYVKNPEAIMKDGELIK 60 Query: 61 DLAKVLKKRISIRPDPDVLLPPEEAEKLIFEIVPKEAEITNIAFDPSVGEVLIEAKKPGL 120 DLAKVLKKRISIRPDPDVLLPPEEAEKLIFEIVPKEAEITNIAFDPSVGEVLIEAKKPGL Sbjct: 61 DLAKVLKKRISIRPDPDVLLPPEEAEKLIFEIVPKEAEITNIAFDPSVGEVLIEAKKPGL 120 Query: 121 VIGKNGETLRLITQKVKWAPKVVRTPPLQSQTIYSIRQILQSESKDRRKFLRQVGRNIYR 180 VIGKNGETLRLITQKVKWAPKVVRTPPLQSQTIYSIRQILQSESKDRRKFLRQVGRNIYR Sbjct: 121 VIGKNGETLRLITQKVKWAPKVVRTPPLQSQTIYSIRQILQSESKDRRKFLRQVGRNIYR 180 Query: 181 KPEYKSRWIRITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEF 240 KPEYKSRWIRITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEF Sbjct: 181 KPEYKSRWIRITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEF 240 Query: 241 QYVLKEGLLDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQ 300 QYVLKEGLLDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQ Sbjct: 241 QYVLKEGLLDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQ 300 Query: 301 SNGQDPLYRPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLH 360 SNGQDPLYRPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLH Sbjct: 301 SNGQDPLYRPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLH 360 Query: 361 NIAITGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTL 420 NIAITGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTL Sbjct: 361 NIAITGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTL 420 Query: 421 KRGGKVLIPAMAVGRAQEVMMVLEDYARIGAIDAPIYLDGMIWEATAIHTAYPEYLSRRL 480 KRGGKVLIPAMAVGRAQEVMMVLEDYARIGAIDAPIYLDGMIWEATAIHTAYPEYLSRRL Sbjct: 421 KRGGKVLIPAMAVGRAQEVMMVLEDYARIGAIDAPIYLDGMIWEATAIHTAYPEYLSRRL 480 Query: 481 REQIFKEGYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPD 540 REQIFKEGYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPD Sbjct: 481 REQIFKEGYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPD 540 Query: 541 PRNSIIFVSYQAEGTLGRQVQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRREL 600 PRNSIIFVSYQAEGTLGRQVQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRREL Sbjct: 541 PRNSIIFVSYQAEGTLGRQVQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRREL 600 Query: 601 MNYVAKVRPRPERVITVHGEPQKCLDLATSIHRKFGLSTRAPNNLDTIRLR 651 MNYVAKVRPRPERVITVHGEPQKCLDLATSIHRKFGLSTRAPNNLDTIRLR Sbjct: 601 MNYVAKVRPRPERVITVHGEPQKCLDLATSIHRKFGLSTRAPNNLDTIRLR 651 >pir||F71013 hypothetical protein PH1404 - Pyrococcus horikoshii >gi|3257827|dbj|BAA30510.1| (AP000006) 651aa long hypothetical protein [Pyrococcus horikoshii] Length = 651 Score = 1272 bits (3256), Expect = 0.0 Identities = 627/651 (96%), Positives = 644/651 (98%) Query: 1 MSALIKRETQVDQILKDIRGIVNQMVPREAKITEIEFEGPELVIYVKNPEAIMKDGELIK 60 M+ LIKRETQVDQIL+DIR +VNQMVP+EAKITEIEFEGPELVIYVKNPEAIMKDGELIK Sbjct: 1 MTFLIKRETQVDQILRDIRAVVNQMVPKEAKITEIEFEGPELVIYVKNPEAIMKDGELIK 60 Query: 61 DLAKVLKKRISIRPDPDVLLPPEEAEKLIFEIVPKEAEITNIAFDPSVGEVLIEAKKPGL 120 DLAKVLKKRIS+RPDP+VLLPPEEAEKLIFEIVPKEAEITNIAFDPSVGEVLIEAKKPGL Sbjct: 61 DLAKVLKKRISVRPDPEVLLPPEEAEKLIFEIVPKEAEITNIAFDPSVGEVLIEAKKPGL 120 Query: 121 VIGKNGETLRLITQKVKWAPKVVRTPPLQSQTIYSIRQILQSESKDRRKFLRQVGRNIYR 180 VIGKNGETLRLITQKVKWAPKVVRTPPLQSQTIYSIRQILQ+ESKDRRKFLRQVGRNIYR Sbjct: 121 VIGKNGETLRLITQKVKWAPKVVRTPPLQSQTIYSIRQILQTESKDRRKFLRQVGRNIYR 180 Query: 181 KPEYKSRWIRITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEF 240 KPEYKSRWIRITGLGGFREVGRSALLVQTDES+VLVDFGVNVA LNDPYKAFPHFDAPEF Sbjct: 181 KPEYKSRWIRITGLGGFREVGRSALLVQTDESFVLVDFGVNVAMLNDPYKAFPHFDAPEF 240 Query: 241 QYVLKEGLLDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQ 300 QYVL+EGLLDAIIITHAHLDH GMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQ Sbjct: 241 QYVLREGLLDAIIITHAHLDHCGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQ 300 Query: 301 SNGQDPLYRPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLH 360 SNGQDPLYRPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLH Sbjct: 301 SNGQDPLYRPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLH 360 Query: 361 NIAITGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTL 420 NIAITGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIH T+ Sbjct: 361 NIAITGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHNTI 420 Query: 421 KRGGKVLIPAMAVGRAQEVMMVLEDYARIGAIDAPIYLDGMIWEATAIHTAYPEYLSRRL 480 KRGGKVLIPAMAVGRAQEVMMVLE+YARIG I+ PIYLDGMIWEATAIHTAYPEYLSRRL Sbjct: 421 KRGGKVLIPAMAVGRAQEVMMVLEEYARIGGIEVPIYLDGMIWEATAIHTAYPEYLSRRL 480 Query: 481 REQIFKEGYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPD 540 REQIFKEGYNPFLSEIFHPVANS+ERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPD Sbjct: 481 REQIFKEGYNPFLSEIFHPVANSRERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPD 540 Query: 541 PRNSIIFVSYQAEGTLGRQVQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRREL 600 P+NSIIFVSYQAEGTLGRQVQSG+REIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRREL Sbjct: 541 PKNSIIFVSYQAEGTLGRQVQSGIREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRREL 600 Query: 601 MNYVAKVRPRPERVITVHGEPQKCLDLATSIHRKFGLSTRAPNNLDTIRLR 651 MNYVAKVRPRPER+ITVHGEPQKCLDLATSIHRKFG+STRAPNNLDTIRLR Sbjct: 601 MNYVAKVRPRPERIITVHGEPQKCLDLATSIHRKFGISTRAPNNLDTIRLR 651 >sp|Q58633|YC36_METJA HYPOTHETICAL PROTEIN MJ1236 >gi|2128070|pir||C64454 hypothetical protein L9328.4 homolog - Methanococcus jannaschii >gi|1591868|gb|AAB99240.1| (U67564) putative mRNA 3'-end processing factor 2 [Methanococcus jannaschii] Length = 634 Score = 769 bits (1964), Expect = 0.0 Identities = 374/641 (58%), Positives = 493/641 (76%), Gaps = 11/641 (1%) Query: 12 DQILKDIRGIVNQMVPREAKITEIEFEGPELVIYVKNPEAIMKDGELIKDLAKVLKKRIS 71 +++L++IR + + P+EAKI +++FEGPE+V+YVKNPE E+IK LAK L+KRIS Sbjct: 4 EEVLENIRKEIIKKSPKEAKIVDVQFEGPEVVVYVKNPEIFTN--EIIKSLAKDLRKRIS 61 Query: 72 IRPDPDVLLPPEEAEKLIFEIVPKEAEITNIAFDPSVGEVLIEAKKPGLVIGKNGETLRL 131 IRPDP VL+ PE A++ I EIVP+EAEITN FD + GEV+IE+KKPGLVIGK G+TL + Sbjct: 62 IRPDPSVLVEPEIAKQKILEIVPEEAEITNFVFDANTGEVIIESKKPGLVIGKEGKTLEM 121 Query: 132 ITQKVKWAPKVVRTPPLQSQTIYSIRQILQSESKDRRKFLRQVGRNIYRKPEYKSR-WIR 190 I + ++WAPK VRTPP+QS+TI +IR L E + ++ LR++GR I+R + WIR Sbjct: 122 IKKAIRWAPKPVRTPPIQSETIKAIRATLYRERHEVKEILRRIGRRIHRDIVVRGDYWIR 181 Query: 191 ITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGLLD 250 ++ LGG REVGRS L VQT ++ VL+D G+NVA + KAFPHFDAPEF +++ LD Sbjct: 182 VSFLGGAREVGRSCLYVQTPDTRVLIDCGINVACED---KAFPHFDAPEFS--IED--LD 234 Query: 251 AIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPLYRP 310 A+I+THAHLDH G +P LFRY +DGP+Y T PTRDLM LLQKD++EI + G++ Y Sbjct: 235 AVIVTHAHLDHCGFIPGLFRYG-YDGPVYCTRPTRDLMTLLQKDYLEIAKKEGKEVPYTS 293 Query: 311 RDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAITGDFKF 370 +DIK +KHTI +DYG DISP I+LTLHNAGH+LGSAI HLHIG GL+N+A TGD KF Sbjct: 294 KDIKTCVKHTIPIDYGVTTDISPTIKLTLHNAGHVLGSAIAHLHIGEGLYNLAYTGDIKF 353 Query: 371 IPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLIPA 430 +RLLEPA +FPRLETL++ESTYG +D+ REEAE+ L+ V+ +T RGGKVLIP Sbjct: 354 ETSRLLEPAVCQFPRLETLIIESTYGAYDDVLPEREEAERELLRVVSETTDRGGKVLIPV 413 Query: 431 MAVGRAQEVMMVLEDYARIGAIDAPIYLDGMIWEATAIHTAYPEYLSRRLREQIFKEGYN 490 VGRAQE+M+VLE+ G +AP+YLDGMIWEATAIHTAYPEYLS+ +R++IF EG N Sbjct: 414 FGVGRAQELMLVLEEGYNQGIFNAPVYLDGMIWEATAIHTAYPEYLSKEMRQKIFHEGDN 473 Query: 491 PFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSIIFVSY 550 PFLSE+F V ++ ER+ +IDS+EP +I+A+SGML GGPSVEY K LAPD +N+IIFV Y Sbjct: 474 PFLSEVFKRVGSTNERRKVIDSDEPCVILATSGMLTGGPSVEYLKHLAPDEKNAIIFVGY 533 Query: 551 QAEGTLGRQVQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRRELMNYVAKVRPR 610 QAEGTLGR+VQSG +EIP++ G+T+ I +N++V+TI+GFSGH+DR++L+ Y+ +++P Sbjct: 534 QAEGTLGRKVQSGWKEIPIITRNGKTKSIPINLQVYTIEGFSGHSDRKQLIKYIRRLKPS 593 Query: 611 PERVITVHGEPQKCLDLATSIHRKFGLSTRAPNNLDTIRLR 651 PE++I VHGE KCLD A ++ R F T P NLD IR++ Sbjct: 594 PEKIIMVHGEESKCLDFADTVRRLFKKQTYVPMNLDAIRVK 634 >pir||F69027 cleavage and polyadenylation specificity factor - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622312|gb|AAB85692.1| (AE000888) cleavage and polyadenylation specificity factor [Methanobacterium thermoautotrophicum] Length = 636 Score = 743 bits (1898), Expect = 0.0 Identities = 359/642 (55%), Positives = 481/642 (74%), Gaps = 8/642 (1%) Query: 11 VDQILKDIRGIVNQMVPREAKITEIEFEGPELVIYVKNPEAIMKDGELIKDLAKVLKKRI 70 V ++L++I+ + Q +P ++ ++EFEGPE+VIY KNPE I ++G LI+D+AK ++KRI Sbjct: 2 VSEMLEEIKRTIMQRLPERVQVAKVEFEGPEVVIYTKNPEIITENGNLIRDIAKDIRKRI 61 Query: 71 SIRPDPDVLLPPEEAEKLIFEIVPKEAEITNIAFDPSVGEVLIEAKKPGLVIGKNGETLR 130 IR D VL+ PE+A + I EIVP+EA+ITNI+FD EV+IEA+KPGLVIGK G T R Sbjct: 62 IIRSDRSVLMDPEKAIRKIHEIVPEEAKITNISFDDVTCEVIIEARKPGLVIGKYGSTSR 121 Query: 131 LITQKVKWAPKVVRTPPLQSQTIYSIRQILQSESKDRRKFLRQVGRNIYRKPEYKSRWIR 190 I + WAPK++RTPP+ S+ I IR+ L+ SK+R+K L+Q+G I++KP+Y + W R Sbjct: 122 EIVKNTGWAPKILRTPPISSEIIERIRRTLRKNSKERKKILQQLGNRIHQKPKYDNDWAR 181 Query: 191 ITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGLLD 250 +T +GGFREVGRS L +QT S VL+D GVNVA D ++P+ + PEF LD Sbjct: 182 LTAMGGFREVGRSCLYLQTPNSRVLLDCGVNVAG-GDDKNSYPYLNVPEFTL----DSLD 236 Query: 251 AIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPLYRP 310 A+IITHAHLDHSG LPYL+ Y +DGP+Y T PTRDLM LLQ D I+I + + Sbjct: 237 AVIITHAHLDHSGFLPYLYHYG-YDGPVYCTAPTRDLMTLLQLDHIDIAHREDEPLPFNV 295 Query: 311 RDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAITGDFKF 370 + +K+ +KHTITLDYGEV DI+PDIRLTLHNAGHILGSA+ HLHIG+G HN+ TGDFK+ Sbjct: 296 KHVKKSVKHTITLDYGEVTDIAPDIRLTLHNAGHILGSAMAHLHIGDGQHNMVYTGDFKY 355 Query: 371 IPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLIPA 430 +RLLE A +FPR+ETLVMESTYGG D+Q R AEK L++ I+ TL+RGGK+LIP Sbjct: 356 EQSRLLEAAANRFPRIETLVMESTYGGHEDVQPSRNRAEKELVKTIYSTLRRGGKILIPV 415 Query: 431 MAVGRAQEVMMVLEDYARIGAID-APIYLDGMIWEATAIHTAYPEYLSRRLREQIFKEGY 489 AVGRAQE+M+VLE+Y R G ID P+Y+DGMIWEA AIHTA PEYLS+ LR+QIF G+ Sbjct: 416 FAVGRAQELMIVLEEYIRTGIIDEVPVYIDGMIWEANAIHTARPEYLSKDLRDQIFHMGH 475 Query: 490 NPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSIIFVS 549 NPF+S+IFH V ER++I++ EP+II+++SGML GG S+EYFK L DP NS++FV Sbjct: 476 NPFISDIFHKVNGMDERREIVE-GEPSIILSTSGMLTGGNSLEYFKWLCEDPDNSLVFVG 534 Query: 550 YQAEGTLGRQVQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRRELMNYVAKVRP 609 YQAEG+LGR++Q G +EIP+ E+ + V V M + TI+GFSGH+DRR+LM YV ++ P Sbjct: 535 YQAEGSLGRRIQKGWKEIPLKDEDDKMRVYNVRMNIKTIEGFSGHSDRRQLMEYVKRISP 594 Query: 610 RPERVITVHGEPQKCLDLATSIHRKFGLSTRAPNNLDTIRLR 651 +PE+++ HG+ K LDLA+SI+R + + T+ P NL+T+R++ Sbjct: 595 KPEKILLCHGDNYKTLDLASSIYRTYRIETKTPLNLETVRIQ 636 >gi|11498093 mRNA 3'-end processing factor, putative [Archaeoglobus fulgidus] >gi|7483885|pir||B69310 mRNA 3'-end processing factor homolog - Archaeoglobus fulgidus >gi|2650146|gb|AAB90756.1| (AE001071) mRNA 3'-end processing factor, putative [Archaeoglobus fulgidus] Length = 632 Score = 707 bits (1806), Expect = 0.0 Identities = 356/636 (55%), Positives = 472/636 (73%), Gaps = 11/636 (1%) Query: 15 LKDIRGIVNQMVPREAKITEIEFEGPELVIYVKNPEAIMKDGELIKDLAKVLKKRISIRP 74 L +IR V + +P + ++ IEFEGP+LVIYV+NP+ + + +++K LAK L+KRI IR Sbjct: 5 LDEIREKVKEYLPPKVRVKSIEFEGPQLVIYVENPQELA-EVDIVKKLAKDLRKRIIIRA 63 Query: 75 DPDVLLPPEEAEKLIFEIVPKEAEITNIAFDPSVGEVLIEAKKPGLVIGKNGETLRLITQ 134 DP L PPE+A ++I +IVP++A I+NI FD GEV+IEA+KPG+VIGK G T R I + Sbjct: 64 DPKSLKPPEKARQIIMQIVPEDARISNIFFDEENGEVIIEAEKPGVVIGKQGSTFREIMR 123 Query: 135 KVKWAPKVVRTPPLQSQTIYSIRQILQSESKDRRKFLRQVGRNIYRKPEYKSRWIRITGL 194 V W+P+VVRTPP++S+ I +IR L S ++R + L+++G I+R +W+R+T L Sbjct: 124 AVGWSPRVVRTPPIKSKIIDNIRNYLLSVREERSEILKRIGERIHRTSLIDEKWVRVTFL 183 Query: 195 GGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGLLDAIII 254 GG REVGRS L+QT ES +L+D GVNV+ L+ P+ PE Q + LDA++I Sbjct: 184 GGSREVGRSCYLLQTPESRILIDCGVNVSNLSST----PYLYVPEVQPL---DALDAVVI 236 Query: 255 THAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPLYRPRDIK 314 THAHLDH G++P L+++ + GPIY TPPTRDLMVLLQ DF+E+ G +P Y I+ Sbjct: 237 THAHLDHCGLVPLLYKFG-YRGPIYLTPPTRDLMVLLQLDFLEVAGREGTNPPYSSNLIR 295 Query: 315 EVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAITGDFKFIPTR 374 E +KHTITLDYG V DISPD+RLT +NAGHILGSAI H HIG G +NIA TGDFKF TR Sbjct: 296 EALKHTITLDYGVVTDISPDVRLTFYNAGHILGSAIAHFHIGEGHYNIAFTGDFKFEKTR 355 Query: 375 LLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLIPAMAVG 434 L + A FPRLE LVME+TYGG ND Q R+EAE+RLIEVI++TL RGGKVLIP AVG Sbjct: 356 LFDRAATNFPRLEALVMEATYGGPNDFQPSRKEAEERLIEVINRTLDRGGKVLIPTFAVG 415 Query: 435 RAQEVMMVLEDYARIGAI-DAPIYLDGMIWEATAIHTAYPEYLSRRLREQIFKEGYNPFL 493 R+QEVM+VLE+ R + + +YLDGMI+EATAIHTAYPEYL+ +LR+ IF G NPF+ Sbjct: 416 RSQEVMIVLEEAMREKRLRETYVYLDGMIYEATAIHTAYPEYLNAQLRDLIFYHGINPFI 475 Query: 494 SEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSIIFVSYQAE 553 SE F V +S +R+++I P+IIIA+SGML GGP +EYF+ LA D RN+I+FV YQAE Sbjct: 476 SENFVRVDSSSKREEVISDPSPSIIIATSGMLNGGPVMEYFRHLAEDERNTIVFVGYQAE 535 Query: 554 GTLGRQVQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRRELMNYVAKVRPRPER 613 GTLGR++Q G +E+P +GR EV++V MEV T+DGFSGH+DR++LMNY+ + +PE+ Sbjct: 536 GTLGRKIQKGWKEVPF-PVDGRREVVEVKMEVETVDGFSGHSDRKQLMNYIRYLNSKPEK 594 Query: 614 VITVHGEPQKCLDLATSIHRKFGLSTRAPNNLDTIR 649 V TVHG+ KC+DLA+SI++ + + TRAP NL+TIR Sbjct: 595 VATVHGDESKCIDLASSIYKTYRIETRAPMNLETIR 630 >gb|AAG18954.1| (AE004996) mRNA 3'-end processing factor homolog; Epf2 [Halobacterium sp. NRC-1] Length = 641 Score = 631 bits (1611), Expect = e-180 Identities = 307/645 (47%), Positives = 451/645 (69%), Gaps = 15/645 (2%) Query: 11 VDQILKDIRGIVNQMVPREAKITEIEFEGPELVIYVKNPEAIMKDGELIKDLAKVLKKRI 70 VD+ L++++ + +P + +T++++EGPELV+Y ++P+ +DG+L++ LA L+KRI Sbjct: 4 VDRQLEELQDEIVSEIPADISVTDVKYEGPELVVYTRDPKQFAQDGDLVRRLASKLRKRI 63 Query: 71 SIRPDPDVLLPPEEAEKLIFEIVPKEAEITNIAFDPSVGEVLIEAKKPGLVIGKNGETLR 130 ++RPDP VL P+ A + +++P+EA +TN+ F GEV+IEA+KPG+VIG++G TLR Sbjct: 64 TVRPDPAVLSSPKRARDRVLDVIPEEAGVTNLDFHEDTGEVVIEAEKPGMVIGRHGSTLR 123 Query: 131 LITQKVKWAPKVVRTPPLQSQTIYSIRQILQSESKDRRKFLRQVGRNIYRKPEYKSRWIR 190 ITQ+ W P+VVRTPP++S T+ ++R L+ E +RR L VGR I+R+ ++R Sbjct: 124 EITQEAGWTPEVVRTPPIESSTVSNVRNFLKQERDERRDILETVGRQIHREEMQDDEYVR 183 Query: 191 ITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALND-PYKAFPHFDAPEFQYVLKEGL- 248 +T LG REVGR++ ++ T E+ +LVD G + ++ PY + Q L G Sbjct: 184 VTTLGCCREVGRASFVLSTPETRILVDCGDKPGSEDEVPYL--------QVQEALAGGAN 235 Query: 249 -LDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPL 307 +DA+I+THAHLDHS +P LF+Y +DGPIY T PTRDLM LL D++++ G+ P Sbjct: 236 TIDAVILTHAHLDHSAFIPLLFKYG-YDGPIYCTEPTRDLMGLLTLDYLDVAAKEGRAPP 294 Query: 308 YRPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAITGD 367 Y ++E IKH I L+YG+V DI+PD++LT HNAGHILGSA+ H HIG+GL+N+A +GD Sbjct: 295 YDSEMVREAIKHCIPLEYGDVTDIAPDVKLTFHNAGHILGSAVSHFHIGDGLYNVAFSGD 354 Query: 368 FKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVL 427 + TRL A FPR+ETLVMESTYGG ND Q +E++E++L VI++T + GGKVL Sbjct: 355 IHYDDTRLFNGAVNDFPRVETLVMESTYGGRNDYQTDQEDSERKLKRVINETYEDGGKVL 414 Query: 428 IPAMAVGRAQEVMMVLEDYARIGAI-DAPIYLDGMIWEATAIHTAYPEYLSRRLREQIFK 486 IPA AVGR+QE+M+VLE+ R G I + PI+LDGMIWEATAIHT YPEYL LR++IF Sbjct: 415 IPAFAVGRSQEMMLVLEEAMREGEIPEMPIHLDGMIWEATAIHTTYPEYLRDDLRDRIFH 474 Query: 487 EGYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSII 546 NPFL+ F+ + +E + + ++ II+++SGM+ GGP + + + +APDP +++ Sbjct: 475 SDSNPFLAPQFNHIDGGEEERQAVADDDQCIILSTSGMVSGGPIMSWLEHIAPDPDSTLT 534 Query: 547 FVSYQAEGTLGRQVQSGVREIPMVGEE--GRTEVIKVNMEVHTIDGFSGHADRRELMNYV 604 FV YQA+GTLGR++QSG +IPM GRTE +++NM V T+DGFSGHADR+ L ++V Sbjct: 535 FVGYQAQGTLGRRIQSGRDKIPMPDSRSGGRTEHLQLNMGVETVDGFSGHADRQGLEDFV 594 Query: 605 AKVRPRPERVITVHGEPQKCLDLATSIHRKFGLSTRAPNNLDTIR 649 + PRPE+V+ VHG+ DL+++++ +F + T AP NL+T R Sbjct: 595 RTMNPRPEKVLCVHGDESSTQDLSSALYHEFNMRTFAPKNLETFR 639 >emb|CAB57542.1| (Y18930) mRNA 3'-end polyadenylation factor [Sulfolobus solfataricus] Length = 639 Score = 619 bits (1580), Expect = e-176 Identities = 309/627 (49%), Positives = 441/627 (70%), Gaps = 14/627 (2%) Query: 28 REAKITEIEFEGPELVIYVKNPEAIMKDGELIKDLAKVLKKRISIRPDPDVLLPPEEAEK 87 +E IT IE+EGP + +YVK P I + GE+IK +AK +KKRI I+ DP V +EA + Sbjct: 22 KELGITRIEYEGPTIAVYVKKPALITEKGEVIKKIAKDIKKRIVIKADPSVRKDKKEAVE 81 Query: 88 LIFEIVPKEAEITNIAFDPSVGEVLIEAKKPGLVIGKNGETLRLITQKVKWAPKVVRTPP 147 +I +VP EAEI +I FD +GEVLI+AKKPGLVIGK G + I + W ++VR PP Sbjct: 82 IIKNLVPAEAEIVDIKFDDDLGEVLIKAKKPGLVIGKGGSLQQRIFAETFWKAEIVREPP 141 Query: 148 LQSQTIYSIRQILQSESKDRRKFLRQVGRNIYRKPEYKSRWIRITGLGGFREVGRSALLV 207 ++S+T SI + + +E++ R K L+ G I+R+ ++ +++RIT LGGF EVGRSA+LV Sbjct: 142 IKSRTYDSILEHIYNETEYRAKILKVFGERIHRETIFQDKYVRITALGGFLEVGRSAVLV 201 Query: 208 QTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGLLDAIIITHAHLDHSGMLPY 267 +T ES VL+D G+N +A K FP D + LK LDA++ITHAHLDH GM+P+ Sbjct: 202 ETPESKVLLDVGLNPSANMFGEKLFPKLDIDQ----LKMEELDAVVITHAHLDHCGMVPF 257 Query: 268 LFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPLYRPRDIKEVIKHTITLDYGE 327 LF+Y ++GP+YTT PTRD+M L+Q D +++ + G+ Y +++++ + HTITLDYGE Sbjct: 258 LFKYG-YEGPVYTTVPTRDIMALMQLDSLDVAEKEGKPIPYSAKEVRKELLHTITLDYGE 316 Query: 328 VRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAITGDFKFIPTRLLEPANAKFPRLE 387 V DI+PDIRLT +NAGHILGS + HLHIG+G HNI TGDFK+ T+LL+ AN +FPR++ Sbjct: 317 VTDIAPDIRLTFYNAGHILGSGMAHLHIGDGKHNIVYTGDFKYAKTKLLDKANTEFPRVD 376 Query: 388 TLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLIPAMAVGRAQEVMMVLEDYA 447 TL+ME+TYG + Q REE+E L+E+I++TL +GGKVLIP +AVGR QE+M+++ D+ Sbjct: 377 TLIMETTYGAQD--QPNREESELELLEIINKTLNKGGKVLIPVLAVGRGQEIMLIINDFM 434 Query: 448 RIGAI-DAPIYLDGMIWEATAIHTAYPEYLSRRLREQIFKEGYNPFLSEIFHPVANSKER 506 + I + P+Y+ G++ E TAIH AYPE+L R +RE+I + NPF SE F + KE Sbjct: 435 KKKLIPEVPVYVTGLVDEVTAIHNAYPEWLGREVREEILYKDENPFTSEHFKRIEGYKED 494 Query: 507 QDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSIIFVSYQAEGTLGRQVQSGVRE 566 I EP+II+A+SGML GGP+VE+FK +APDP+N+IIFVSYQAEGTLGR+V+ G +E Sbjct: 495 ---IAKGEPSIILATSGMLNGGPAVEFFKTMAPDPKNAIIFVSYQAEGTLGRKVRDGAKE 551 Query: 567 IPMVGEEGRTEVIKVNMEVHTIDGFSGHADRRELMNYVAKVRPRPERVITVHGEPQKCLD 626 + ++ +GR E I++NMEV ++GFSGH+D+R+L+N++ + P+P+ VI HGE Sbjct: 552 VQILDRDGRVESIQINMEVEAVEGFSGHSDKRQLLNFLRNIEPKPKNVILNHGEASSIRA 611 Query: 627 LATSIHRK---FGLSTRAPNNLDTIRL 650 A I + + P LD++R+ Sbjct: 612 FANYIREDRLGYKPNIYTPAILDSLRV 638 >gb|AAK41056.1| mRNA 3'-end processing factor, putative [Sulfolobus solfataricus] Length = 639 Score = 619 bits (1580), Expect = e-176 Identities = 309/627 (49%), Positives = 441/627 (70%), Gaps = 14/627 (2%) Query: 28 REAKITEIEFEGPELVIYVKNPEAIMKDGELIKDLAKVLKKRISIRPDPDVLLPPEEAEK 87 +E IT IE+EGP + +YVK P I + GE+IK +AK +KKRI I+ DP V +EA + Sbjct: 22 KELGITRIEYEGPTIAVYVKKPALITEKGEVIKKIAKDIKKRIVIKADPSVRKDKKEAVE 81 Query: 88 LIFEIVPKEAEITNIAFDPSVGEVLIEAKKPGLVIGKNGETLRLITQKVKWAPKVVRTPP 147 +I +VP EAEI +I FD +GEVLI+AKKPGLVIGK G + I + W ++VR PP Sbjct: 82 IIKNLVPAEAEIVDIKFDDDLGEVLIKAKKPGLVIGKGGSLQQRIFAETFWKAEIVREPP 141 Query: 148 LQSQTIYSIRQILQSESKDRRKFLRQVGRNIYRKPEYKSRWIRITGLGGFREVGRSALLV 207 ++S+T SI + + +E++ R K L+ G I+R+ ++ +++RIT LGGF EVGRSA+LV Sbjct: 142 IKSRTYDSILEHIYNETEYRAKILKVFGERIHRETIFQDKYVRITALGGFLEVGRSAVLV 201 Query: 208 QTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGLLDAIIITHAHLDHSGMLPY 267 +T ES VL+D G+N +A K FP D + LK LDA++ITHAHLDH GM+P+ Sbjct: 202 ETPESKVLLDVGLNPSANMFGEKLFPKLDIDQ----LKMEELDAVVITHAHLDHCGMVPF 257 Query: 268 LFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPLYRPRDIKEVIKHTITLDYGE 327 LF+Y ++GP+YTT PTRD+M L+Q D +++ + G+ Y +++++ + HTITLDYGE Sbjct: 258 LFKYG-YEGPVYTTVPTRDIMALMQLDSLDVAEKEGKPIPYSAKEVRKELLHTITLDYGE 316 Query: 328 VRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAITGDFKFIPTRLLEPANAKFPRLE 387 V DI+PDIRLT +NAGHILGS + HLHIG+G HNI TGDFK+ T+LL+ AN +FPR++ Sbjct: 317 VTDIAPDIRLTFYNAGHILGSGMAHLHIGDGKHNIVYTGDFKYAKTKLLDKANTEFPRVD 376 Query: 388 TLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLIPAMAVGRAQEVMMVLEDYA 447 TL+ME+TYG + Q REE+E L+E+I++TL +GGKVLIP +AVGR QE+M+++ D+ Sbjct: 377 TLIMETTYGAQD--QPNREESELELLEIINKTLNKGGKVLIPVLAVGRGQEIMLIINDFM 434 Query: 448 RIGAI-DAPIYLDGMIWEATAIHTAYPEYLSRRLREQIFKEGYNPFLSEIFHPVANSKER 506 + I + P+Y+ G++ E TAIH AYPE+L R +RE+I + NPF SE F + KE Sbjct: 435 KKKLIPEVPVYVTGLVDEVTAIHNAYPEWLGREVREEILYKDENPFTSEHFKRIEGYKED 494 Query: 507 QDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSIIFVSYQAEGTLGRQVQSGVRE 566 I EP+II+A+SGML GGP+VE+FK +APDP+N+IIFVSYQAEGTLGR+V+ G +E Sbjct: 495 ---IAKGEPSIILATSGMLNGGPAVEFFKTMAPDPKNAIIFVSYQAEGTLGRKVRDGAKE 551 Query: 567 IPMVGEEGRTEVIKVNMEVHTIDGFSGHADRRELMNYVAKVRPRPERVITVHGEPQKCLD 626 + ++ +GR E I++NMEV ++GFSGH+D+R+L+N++ + P+P+ VI HGE Sbjct: 552 VQILDRDGRVESIQINMEVEAVEGFSGHSDKRQLLNFLRNIEPKPKNVILNHGEASSIRA 611 Query: 627 LATSIHRK---FGLSTRAPNNLDTIRL 650 A I + + P LD++R+ Sbjct: 612 FANYIREDRLGYKPNIYTPAILDSLRV 638 >pir||C72749 probable cleavage and polyadenylation factor subunit APE0522 - Aeropyrum pernix (strain K1) >gi|5104171|dbj|BAA79487.1| (AP000059) 676aa long hypothetical cleavage and polyadenylation factor subunit [Aeropyrum pernix] Length = 676 Score = 542 bits (1381), Expect = e-153 Identities = 284/637 (44%), Positives = 417/637 (64%), Gaps = 24/637 (3%) Query: 28 REAKITEIEFEGPELVIYVKNPEAIMKDGELIKDLAKVLKKRISIRPDPDVLLPPEEAEK 87 R A I IEFEGPE+ +Y++NP+ I+++ ++KDLA+ L+KRI +R P E K Sbjct: 36 RSADIASIEFEGPEIAVYIRNPKFIVENENVVKDLARKLRKRIVVRTHPKSRKSMEYTIK 95 Query: 88 LIFEIVPKEAEITNIAFDPSVGEVLIEAKKPGLVIGKNGETLRLITQKVKWAPKVVRTPP 147 I E VP + I +I FD +GEV + A+KPG ++G+ L+ + W +V R P Sbjct: 96 FIRENVPPDVGIVDIQFDDVLGEVRVIAEKPGKLMGRGKVFRNLVLAETGWRLEVYRKPL 155 Query: 148 LQSQTIYSIRQILQSESKDRRKFLRQVGRNIYRKPEYKSRWIRITGLGGFREVGRSALLV 207 LQS + S+ + LQ +++RR+ LR +G I+R +R +R+ GLG F EVGRSA+LV Sbjct: 156 LQSGLLDSVLRHLQRHAEERRRALRDIGERIFRDTLIGTRHVRVVGLGSFGEVGRSAILV 215 Query: 208 QTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGLLDAIIITHAHLDHSGMLPY 267 T ES VL+D G++ + ++P++ +PEF + LDA++I+HAHLDH G LP Sbjct: 216 DTGESKVLLDAGLSPSGYGP--DSYPYYWSPEF----RVDELDAVVISHAHLDHVGTLPL 269 Query: 268 LFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPLYRPRDIKEVIKHTITLDYGE 327 LF+Y F GP+Y TPPTRD+M+++ +D I + + +P + PRD+++ + I ++Y Sbjct: 270 LFKYG-FRGPVYATPPTRDIMIIVLRDLINLMRKAQGEPPFEPRDVEKALTRLIPVNYNT 328 Query: 328 VRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAITGDFKFI------PTRLLEPANA 381 V D++PDI++T NAGHILGS++VHLHIG GL+NI T DFKF TRLL PA Sbjct: 329 VTDVAPDIKMTFINAGHILGSSMVHLHIGQGLYNILYTADFKFYRIKNDRSTRLLPPAEY 388 Query: 382 KFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLIPAMAVGRAQEVMM 441 F R+E L+ME+TYG PR EAE+ LI ++++ KRGGK+LIP MAVGR QE+++ Sbjct: 389 SFQRVEALIMEATYGSKE--TQPRAEAEEELINLVNKVYKRGGKLLIPVMAVGRGQEILV 446 Query: 442 VLEDYARIGAI-DAPIYLDGMIWEATAIHTAYPEYLSRRLREQIFKEGYNPFLSEIFHPV 500 VL + R G I + PIY+DGM++E TA++T YPE L + +R++I K+G NPF V Sbjct: 447 VLNEALRSGKIPEIPIYVDGMVYEVTAVYTNYPELLVKPIRDRILKQGENPFEGPTTVYV 506 Query: 501 ANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSIIFVSYQAEGTLGRQV 560 + +R + + S++PAII+++SGM+ GGP VEYFK LA DPRN++ FVSYQA GTLGR++ Sbjct: 507 TDHYKRDEAMYSDKPAIILSTSGMMNGGPIVEYFKYLADDPRNALAFVSYQAPGTLGRRL 566 Query: 561 QSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRRELMNYVAKVRPRPERVITVHGE 620 QSG REI + +G IKVNME+ +I+GF+GH+ R EL++++ ++ P+P ++ HGE Sbjct: 567 QSGEREIEL-EMDGGIRRIKVNMEIVSIEGFTGHSTRGELLSFLRRLNPKPRNIVLNHGE 625 Query: 621 PQKCLDLATSIH---RKFGLST----RAPNNLDTIRL 650 P LA ++ K G + AP NL+ +RL Sbjct: 626 PSAIAALAHTVKTGWSKLGFESPPIIEAPENLEGVRL 662 >emb|CAC11752.1| (AL445064) conserved hypothetical protein [Thermoplasma acidophilum] Length = 497 Score = 481 bits (1225), Expect = e-134 Identities = 240/488 (49%), Positives = 336/488 (68%), Gaps = 7/488 (1%) Query: 15 LKDIRGIVNQMVPREAKITEIEFEGPELVIYVKNPEAIMKDGELIKDLAKVLKKRISIRP 74 +++ + I N++ P + KIT+I++EGP +V+Y K+PE K +L++ +A+ +++RI+IR Sbjct: 7 IEETKNIFNRLYP-DNKITDIDYEGPTIVVYTKDPELFAKRDDLVRQIAQEIRRRIAIRS 65 Query: 75 DPDVLLPPEEAEKLIFEIVPKEAEITNIAFDPSVGEVLIEAKKPGLVIGKNGETLRLITQ 134 DP +LLP ++A + I +I+PKEA + +I F+P GEV+IE +P +V + + ++ I Sbjct: 66 DPSILLPEDQARESIEKIIPKEAGLEDIYFEPDTGEVIIELDEPSIVTARGTDYVQEIKS 125 Query: 135 KVKWAPKVVRTPPLQSQTIYSIRQILQSESKDRRKFLRQVGRNIYRKPEYKSRWIRITGL 194 + +W+P++VR PP+ S+T+ +R+ ++ ++RR+FL +G + P W+R+T L Sbjct: 126 RTQWSPRIVRAPPMYSRTVKEVREFMREVKQERREFLHNLGVKLSGPPMVGETWVRLTAL 185 Query: 195 GGFREVGRSALLVQTDESYVLVDFGV-NVAALNDPYKAFPHFDAPEFQYVLKEGLLDAII 253 GG EVGRSA LV T S VL+D G+ NV DP+ A P+ PE Q + +DA+I Sbjct: 186 GGHSEVGRSATLVSTKNSKVLIDCGMMNVGPDADPWDAAPYLYVPEVQPL---STIDAVI 242 Query: 254 ITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPLYRPRDI 313 +THAHLDHSG+LP LF+Y +DGP+Y TPPTRDL LLQ D+I++ + G Y + I Sbjct: 243 LTHAHLDHSGLLPLLFKYG-YDGPVYMTPPTRDLAALLQNDYIKVARMEGGKVPYESKYI 301 Query: 314 KEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAITGDFKFIPT 373 +E +KHTITL YGE DI+ D+RLT +NAGHILGSA HLHIG+GL+N+ ++GD KF T Sbjct: 302 REELKHTITLRYGETTDITRDMRLTFYNAGHILGSASGHLHIGDGLYNVVLSGDVKFEKT 361 Query: 374 RLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLIPAMAV 433 L PAN KFPR ET + ESTYGG +D REEA + LI+VI++T RGG VLIP AV Sbjct: 362 WLFNPANNKFPRAETFMTESTYGGRDDYSFTREEATQTLIDVINRTHDRGGSVLIPVFAV 421 Query: 434 GRAQEVMMVLEDYARIGAI-DAPIYLDGMIWEATAIHTAYPEYLSRRLREQIFKEGYNPF 492 GR+QEVM+VLED R G I +YLDGMI EA AIH AYPEYL++ LRE I + NPF Sbjct: 422 GRSQEVMIVLEDAMRNGRIPQMDVYLDGMIMEAPAIHAAYPEYLNKELREAIMVKKENPF 481 Query: 493 LSEIFHPV 500 LS IF V Sbjct: 482 LSPIFKKV 489 >sp|Q57626|Y162_METJA HYPOTHETICAL PROTEIN MJ0162 >gi|2129218|pir||C64320 probable membrane protein YLR277c homolog - Methanococcus jannaschii >gi|1590919|gb|AAB98146.1| (U67473) putative mRNA 3'-end processing factor 3 [Methanococcus jannaschii] Length = 421 Score = 267 bits (676), Expect = 2e-70 Identities = 158/451 (35%), Positives = 259/451 (57%), Gaps = 48/451 (10%) Query: 195 GGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGLLDAIII 254 GG +++G S + V+T + VL+D G++ D E V + +DA+I+ Sbjct: 8 GGCQQIGMSCVEVETQKGRVLLDCGMSP-------------DTGEIPKV-DDKAVDAVIV 53 Query: 255 THAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPLYRPRDIK 314 +HAHLDH G +P+ +++ IY T PT DLM + +D + + ++ Y+ DI+ Sbjct: 54 SHAHLDHCGAIPF-YKFK----KIYCTHPTADLMFITWRDTLNLTKA------YKEEDIQ 102 Query: 315 EVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAITGDFKFIPTR 374 +++ L+Y E R I+ +I+ +NAGHILGSA ++L + I TGD +R Sbjct: 103 HAMENIECLNYYEERQITENIKFKFYNAGHILGSASIYLEVDG--KKILYTGDINEGVSR 160 Query: 375 LLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLIPAMAVG 434 L PA+ ++ L++ESTYG DI+ R+ E++LIE I +T++ GGKV+IP A+G Sbjct: 161 TLLPADTDIDEIDVLIIESTYGSPLDIKPARKTLERQLIEEISETIENGGKVIIPVFAIG 220 Query: 435 RAQEVMMVLEDYARIGAI-DAPIYLDGMIWEATAIHTAYPEYLSRRLREQIFKEGYNPFL 493 RAQE+++++ +Y R G + D PIY DG + ATA++ +Y +L+ +++ + + NPF Sbjct: 221 RAQEILLIINNYIRSGKLRDVPIYTDGSLIHATAVYMSYINWLNPKIKNMV-ENRINPF- 278 Query: 494 SEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSIIFVSYQAE 553 EI K + ++ + EP II+++SGM+ GGP ++Y K L DP+N +I YQAE Sbjct: 279 GEI------KKADESLVFNKEPCIIVSTSGMVQGGPVLKYLK-LLKDPKNKLILTGYQAE 331 Query: 554 GTLGRQVQSGVREIPMVGEE--GRTEVIKVNMEVHTIDGFSGHADRRELMNYVAKVRPRP 611 GTLGR+++ G +EI + R +V+K+ FS H D L+ Y+ K+ P+P Sbjct: 332 GTLGRELEEGAKEIQPFKNKIPIRGKVVKIE--------FSAHGDYNSLVRYIKKI-PKP 382 Query: 612 ERVITVHGEPQKCLDLATSIHRKFGLSTRAP 642 E+ I +HGE + L A +I + + T P Sbjct: 383 EKAIVMHGERYQSLSFAMTIWKTLKIPTFVP 413 >gb|AAK40713.1| mRNA 3'-end processing factor, putative [Sulfolobus solfataricus] Length = 492 Score = 218 bits (549), Expect = 2e-55 Identities = 150/458 (32%), Positives = 243/458 (52%), Gaps = 44/458 (9%) Query: 194 LGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGLLDAII 253 LGG REVGRSA+ V + +++D+GVN F D P F G + + Sbjct: 78 LGGGREVGRSAIEVGNSDGSIILDYGVN----------FDEKDNPNFPLQEMPGKVKGFV 127 Query: 254 ITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPLYRPRDI 313 ++HAHLDH G LP +++ + +Y T TR + + KDF+++ +G Y ++ Sbjct: 128 VSHAHLDHIGALP-IYQIGSLNTKVYGTVATRIITETMLKDFLKL---SGAKIPYEWVEV 183 Query: 314 KEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAITGDFKFIPT 373 ++ + + + + YGE +I ++++L+NAGHI GS+I+ + G+ IA TGD T Sbjct: 184 RKTMDNFMAIGYGEEVEID-SLKVSLYNAGHIPGSSIIKVSSEKGV--IAFTGDINLTET 240 Query: 374 RLLEPANAK-FPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLIPAMA 432 +L++PA + LVMESTYG N R++ E + + + ++ GG VL+PA + Sbjct: 241 KLMKPAEIENIGDANVLVMESTYGKFNHPN--RKDVENDFYDKVMEVVESGGTVLVPAFS 298 Query: 433 VGRAQEVMMVLEDYARIGAIDAPIYLDGMIWEATAIHTAYPEYLSRRLREQIFKEGYNPF 492 + R+QEV+ VL + P+Y DGM E T I + E+L+R + K+ Y+ F Sbjct: 299 LARSQEVLSVLAERN----FPYPVYYDGMSREITEIMLGFKEFLNR---PDLLKKAYDNF 351 Query: 493 LSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSIIFVSYQA 552 + V ++R E +I+AS+GML GGP+V YFK+L+ + +N++ VSYQA Sbjct: 352 -----NYVKGWEDRHRAW--KEKGVIVASAGMLKGGPAVYYFKKLSENSKNAVFLVSYQA 404 Query: 553 EGTLGRQVQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRRELMNYVAKVRPRPE 612 T GR++ + M + + ++K +E+ FS HA RR+L+ V V+ E Sbjct: 405 INTPGRKL------LEMGKFDEYSGLLKARLEIF---DFSSHAGRRQLLEIVKSVKDL-E 454 Query: 613 RVITVHGEPQKCLDLATSIHRKFGLSTRAPNNLDTIRL 650 +V+ VHG P LA I ++ G+ P N I L Sbjct: 455 KVVLVHGSPDNESSLADLIKQEIGVEVITPENGQEISL 492 >pir||G64305 hypothetical protein YLR277c homolog - Methanococcus jannaschii Length = 435 Score = 214 bits (540), Expect = 2e-54 Identities = 157/434 (36%), Positives = 229/434 (52%), Gaps = 49/434 (11%) Query: 195 GGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGLL---DA 251 G EVGRS + ++TD+S +L+D GV + E +Y + + + D Sbjct: 14 GAALEVGRSCIEIKTDKSKILLDCGVKLGK--------------EIEYPILDNSIRDVDK 59 Query: 252 IIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPLYRPR 311 + I+HAHLDHSG LP LF + D P+ TT ++ L+ +L KD ++I ++ + Y Sbjct: 60 VFISHAHLDHSGALPVLFHRKM-DVPVITTELSKKLIKVLLKDMVKIAETENKKIPYNNH 118 Query: 312 DIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAITGDFKFI 371 D+KE I+HTI L+Y + + D L +AGHI GSA + L+ N I TGD K Sbjct: 119 DVKEAIRHTIPLNYND-KKYYKDFSYELFSAGHIPGSASILLNYQNN-KTILYTGDVKLR 176 Query: 372 PTRLLEPANAKFPR--LETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLIP 429 TRL + A+ + + ++ L++ESTYG N I R+ E IE I + L RGG LIP Sbjct: 177 DTRLTKGADLSYTKDDIDILIIESTYG--NSIHPDRKAVELSFIEKIKEILFRGGVALIP 234 Query: 430 AMAVGRAQEVMMVLEDYARIGAIDAPIYLDGMIWEATAIHTAYPEYLSRRLREQIFKEGY 489 AV RAQE++++L DY IDAPIYLDGM E T + Y L+ Q+ K Sbjct: 235 VFAVDRAQEILLILNDY----NIDAPIYLDGMAVEVTKLMLNYKHMLNE--SSQLEKALK 288 Query: 490 NPFLSEIFHPVANSKERQDIID--SNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSIIF 547 N + E S++R I+ S I++ ++GML GGP + Y K +P+N+++ Sbjct: 289 NVKIIE------KSEDRIKAIENLSKNGGIVVTTAGMLDGGPILYYLKLFMHNPKNALLL 342 Query: 548 VSYQAEGTLGRQ-VQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRRELMNYVAK 606 YQ + GR +++G I G+ E IK N+EV + FS HA EL + K Sbjct: 343 TGYQVRDSNGRHLIETGKIFI------GKDE-IKPNLEV-CMYNFSCHAGMDELHEIIKK 394 Query: 607 VRPRPERVITVHGE 620 V PE +I HGE Sbjct: 395 V--NPELLIIQHGE 406 >sp|Q60355|Y047_METJA HYPOTHETICAL PROTEIN MJ0047 >gi|2826239|gb|AAB98027.1| (U67462) putative mRNA 3'-end processing factor 1 [Methanococcus jannaschii] Length = 428 Score = 214 bits (540), Expect = 2e-54 Identities = 157/434 (36%), Positives = 229/434 (52%), Gaps = 49/434 (11%) Query: 195 GGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGLL---DA 251 G EVGRS + ++TD+S +L+D GV + E +Y + + + D Sbjct: 7 GAALEVGRSCIEIKTDKSKILLDCGVKLGK--------------EIEYPILDNSIRDVDK 52 Query: 252 IIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPLYRPR 311 + I+HAHLDHSG LP LF + D P+ TT ++ L+ +L KD ++I ++ + Y Sbjct: 53 VFISHAHLDHSGALPVLFHRKM-DVPVITTELSKKLIKVLLKDMVKIAETENKKIPYNNH 111 Query: 312 DIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAITGDFKFI 371 D+KE I+HTI L+Y + + D L +AGHI GSA + L+ N I TGD K Sbjct: 112 DVKEAIRHTIPLNYND-KKYYKDFSYELFSAGHIPGSASILLNYQNN-KTILYTGDVKLR 169 Query: 372 PTRLLEPANAKFPR--LETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLIP 429 TRL + A+ + + ++ L++ESTYG N I R+ E IE I + L RGG LIP Sbjct: 170 DTRLTKGADLSYTKDDIDILIIESTYG--NSIHPDRKAVELSFIEKIKEILFRGGVALIP 227 Query: 430 AMAVGRAQEVMMVLEDYARIGAIDAPIYLDGMIWEATAIHTAYPEYLSRRLREQIFKEGY 489 AV RAQE++++L DY IDAPIYLDGM E T + Y L+ Q+ K Sbjct: 228 VFAVDRAQEILLILNDY----NIDAPIYLDGMAVEVTKLMLNYKHMLNE--SSQLEKALK 281 Query: 490 NPFLSEIFHPVANSKERQDIID--SNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSIIF 547 N + E S++R I+ S I++ ++GML GGP + Y K +P+N+++ Sbjct: 282 NVKIIE------KSEDRIKAIENLSKNGGIVVTTAGMLDGGPILYYLKLFMHNPKNALLL 335 Query: 548 VSYQAEGTLGRQ-VQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRRELMNYVAK 606 YQ + GR +++G I G+ E IK N+EV + FS HA EL + K Sbjct: 336 TGYQVRDSNGRHLIETGKIFI------GKDE-IKPNLEV-CMYNFSCHAGMDELHEIIKK 387 Query: 607 VRPRPERVITVHGE 620 V PE +I HGE Sbjct: 388 V--NPELLIIQHGE 399 >gb|AAF56931.1| (AE003771) CG1972 gene product [Drosophila melanogaster] Length = 597 Score = 213 bits (536), Expect = 6e-54 Identities = 141/465 (30%), Positives = 243/465 (51%), Gaps = 31/465 (6%) Query: 189 IRITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGL 248 I+IT LG ++VGRS LL+ +++D G+++ ND + P+F Y++ EG Sbjct: 4 IKITPLGAGQDVGRSCLLLSMGGKNIMLDCGMHMG-YNDERRF------PDFSYIVPEGP 56 Query: 249 L----DAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQ-QSNG 303 + D +II+H HLDH G LPY+ + GPIY T PT+ + +L +D ++ + G Sbjct: 57 ITSHIDCVIISHFHLDHCGALPYMSEIVGYTGPIYMTHPTKAIAPILLEDMRKVAVERKG 116 Query: 304 QDPLYRPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIA 363 + + + IK+ +K I + + + D+ + + AGH+LG+A+ + +G+ ++ Sbjct: 117 ESNFFTTQMIKDCMKKVIPVTLHQSMMVDTDLEIKAYYAGHVLGAAMFWIKVGS--QSVV 174 Query: 364 ITGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRG 423 TGD+ P R L A R + L+ ESTY A I+ + E+ ++ +H+ + +G Sbjct: 175 YTGDYNMTPDRHLGAAWIDKCRPDLLISESTY--ATTIRDSKRCRERDFLKKVHECVAKG 232 Query: 424 GKVLIPAMAVGRAQEVMMVLEDYARIGAIDAPIYLD-GMIWEATAIHTAYPEYLSRRLRE 482 GKVLIP A+GRAQE+ ++LE Y + PIY G+ +A + + + ++++R+ Sbjct: 233 GKVLIPVFALGRAQELCILLETYWERMNLKYPIYFALGLTEKANTYYKMFITWTNQKIRK 292 Query: 483 QIFKEGYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPR 542 N F + P + ID+ ++ A+ GML G S++ FK+ AP+ Sbjct: 293 TFVHR--NMFDFKHIKPFDKA-----YIDNPGAMVVFATPGMLHAGLSLQIFKKWAPNEN 345 Query: 543 NSIIFVSYQAEGTLGRQVQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRRELMN 602 N +I Y +GT+G ++ G +++ E +V++V M V + FS HAD + +M Sbjct: 346 NMVIMPGYCVQGTVGNKILGGAKKV----EFENRQVVEVKMAVEYM-SFSAHADAKGIMQ 400 Query: 603 YVAKVRPRPERVITVHGEPQKCLDLATSIHRKFGLSTRAPNNLDT 647 + P+ V+ VHGE K L + I +F L T P N +T Sbjct: 401 LIQNCEPK--NVMLVHGEAGKMKFLRSKIKDEFNLETYMPANGET 443 >pir||T20694 hypothetical protein F10B5.8 - Caenorhabditis elegans >gi|5824432|emb|CAB54223.1| (Z48334) cDNA EST yk559f4.5 comes from this gene [Caenorhabditis elegans] Length = 474 Score = 210 bits (528), Expect = 5e-53 Identities = 138/467 (29%), Positives = 241/467 (51%), Gaps = 33/467 (7%) Query: 189 IRITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEG- 247 I+I LG ++VGRS +L+ ++VD G+++ +D + FP +F Y+ G Sbjct: 8 IKIVPLGAGQDVGRSCILITIGGKNIMVDCGMHMGYQDD--RRFP-----DFSYIGGGGR 60 Query: 248 ---LLDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQ-QSNG 303 LD +II+H HLDH G LP++ +DGPIY T PT+ + +L +D+ ++Q G Sbjct: 61 LTDYLDCVIISHFHLDHCGSLPHMSEIVGYDGPIYMTYPTKAICPVLLEDYRKVQCDIKG 120 Query: 304 QDPLYRPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIA 363 + + DIK +K + E+ + ++ + AGH+LG+A+ + +G+ H++ Sbjct: 121 ETNFFTSDDIKNCMKKVVGCALHEIIHVDNELSIRAFYAGHVLGAAMFEIRLGD--HSVL 178 Query: 364 ITGDFKFIPTRLLEPANA-KFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKR 422 TGD+ P R L A R L+ ESTY A I+ + E+ + +H+ + + Sbjct: 179 YTGDYNMTPDRHLGAARVLPGVRPTVLISESTY--ATTIRDSKRARERDFLRKVHECVMK 236 Query: 423 GGKVLIPAMAVGRAQEVMMVLEDYARIGAIDAPIYL-DGMIWEATAIHTAYPEYLSRRLR 481 GGKV+IP A+GRAQE+ ++LE Y A++ PIY G+ A + + + + ++ Sbjct: 237 GGKVIIPVFALGRAQELCILLESYWERMALNVPIYFSQGLAERANQYYRLFISWTNENIK 296 Query: 482 EQIFKEGYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDP 541 + + N F + P+ E D P ++ ++ GML GG S++ FK+ DP Sbjct: 297 KTFVER--NMFEFKHIKPMEKGCE-----DQPGPQVLFSTPGMLHGGQSLKVFKKWCSDP 349 Query: 542 RNSIIFVSYQAEGTLGRQVQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRRELM 601 N II Y GT+G +V +G ++I + + + I++ +E + FS HAD + +M Sbjct: 350 LNMIIMPGYCVAGTVGARVINGEKKIEI---DQKMHEIRLGVEYMS---FSAHADAKGIM 403 Query: 602 NYVAKVRPRPERVITVHGEPQKCLDLATSIHRKFGLSTRAPNNLDTI 648 + + P+ V+ VHGE K L + +++ + P N +T+ Sbjct: 404 QLIRQC--EPQHVMFVHGEASKMEFLKGKVEKEYKVPVHMPANGETV 448 >gi|11498143 mRNA 3'-end processing factor, putative [Archaeoglobus fulgidus] >gi|7483886|pir||D69316 mRNA 3'-end processing factor homolog - Archaeoglobus fulgidus >gi|2650088|gb|AAB90702.1| (AE001067) mRNA 3'-end processing factor, putative [Archaeoglobus fulgidus] Length = 407 Score = 209 bits (526), Expect = 9e-53 Identities = 154/457 (33%), Positives = 237/457 (51%), Gaps = 62/457 (13%) Query: 191 ITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGLLD 250 I LGG REVGRSA++V +++D+GV + D PEF GL Sbjct: 4 INFLGGCREVGRSAVMVDG----IMIDYGVKPS------------DPPEFPL---NGLSP 44 Query: 251 -AIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPLYR 309 A+I++H HLDH G+ P L Y D + TPP+ +L ++L +D ++I P + Sbjct: 45 RAVILSHGHLDHIGVAPNLMYY---DPEVILTPPSHELSMILLRDSMKIMHP----PPFT 97 Query: 310 PRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAITGDFK 369 R++++ + ++Y E + D + NAGHI GSA +H+ G NI +GD + Sbjct: 98 KRELRQFESNIREVEYEEPITVG-DYEVEFFNAGHIPGSASIHMR---GDVNILYSGDIR 153 Query: 370 FIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLIP 429 TRLLE AN +P + L++ESTY G R+E E+ +E + TL GG +IP Sbjct: 154 LEETRLLEGANTDYPETDILIVESTYFGTE--HPDRKELERAFVESVIDTLDMGGHAIIP 211 Query: 430 AMAVGRAQEVMMVLEDYARIGAIDAPIYLDGMIWEATAIHTAYPEYLSRRLREQIFKEGY 489 A AVGR QEV+M+LE Y Y+DGM E + +P+++ R +++ + Sbjct: 212 AFAVGRTQEVLMILERYG------ITPYVDGMGKEVAQVIQRHPDFI--RSPKELKRAVR 263 Query: 490 NPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSIIFVS 549 N PV ++R+ +++ EP+ ++ ++GML GGP++ Y +L D ++ I+ Sbjct: 264 NAI------PV-EWRQRERVLE--EPSAVVTTAGMLNGGPAMFYISRLYNDEKSKILLTG 314 Query: 550 YQAEGTLG-RQVQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRRELMNYVAKVR 608 YQ EGT G +++G+ + T V+K+ M V D FS HAD R+L YV +V Sbjct: 315 YQVEGTNGDMALKTGMLNL-------GTRVVKLKMGVEQYD-FSAHADDRQLKEYVKRVV 366 Query: 609 PR-PERVITVHGEPQKCLDLATSIHRKFGLSTRAPNN 644 R E V T+HGE + A I G+ AP N Sbjct: 367 DRGAEVVFTIHGEETEA--FAEWIKDNIGVEAYAPKN 401 >pir||T37848 probable cleavage and polyadenylation specifity factor - fission yeast (Schizosaccharomyces pombe) >gi|2408029|emb|CAB16227.1| (Z99162) putative cleavage and polyadenylation specifity factor [Schizosaccharomyces pombe] Length = 775 Score = 204 bits (513), Expect = 3e-51 Identities = 140/450 (31%), Positives = 226/450 (50%), Gaps = 29/450 (6%) Query: 189 IRITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGL 248 + LG EVGRS ++Q V++D GV+ A A P FD + V Sbjct: 37 LEFINLGAGNEVGRSCHVIQYKGKTVMLDAGVHPAYTG--LSALPFFDEFDLSTV----- 89 Query: 249 LDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPLY 308 D ++I+H HLDH LPY+ + F G ++ T PT+ + L D++++ +D LY Sbjct: 90 -DVLLISHFHLDHVASLPYVMQKTNFRGRVFMTHPTKAVCKWLLSDYVKVSNVGMEDQLY 148 Query: 309 RPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAITGDF 368 +D+ +DY ++ I+ T ++AGH+LG+ + + + NI TGD+ Sbjct: 149 DEKDLLAAFDRIEAVDYHSTIEVE-GIKFTPYHAGHVLGACMYFVEMAGV--NILFTGDY 205 Query: 369 KFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLI 428 R L A R + L+ ESTYG A+ PR E E RL+ +IH T++ GG+VL+ Sbjct: 206 SREEDRHLHVAEVPPKRPDVLITESTYGTAS--HQPRLEKEARLLNIIHSTIRNGGRVLM 263 Query: 429 PAMAVGRAQEVMMVLEDY--ARIGAIDAPI-YLDGMIWEATAIHTAYPEYLSRRLREQIF 485 P A+GRAQE++++L++Y + PI Y + + AI Y ++ +R +IF Sbjct: 264 PVFALGRAQELLLILDEYWNNHLDLRSVPIYYASSLARKCMAIFQTYVNMMNDNIR-KIF 322 Query: 486 KEGYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSI 545 E NPF+ + N ++ DI P++I+AS GML G S ++ APDPRN++ Sbjct: 323 AE-RNPFIFRFVKSLRNLEKFDDI----GPSVILASPGMLQNGVSRTLLERWAPDPRNTL 377 Query: 546 IFVSYQAEGTLGRQVQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRRELMNYVA 605 + Y EGT+ +Q+ + I +V G + I M V + F+ H D + ++ Sbjct: 378 LLTGYSVEGTMAKQITN--EPIEIVSLSG--QKIPRRMAVEEL-SFAAHVDYLQNSEFID 432 Query: 606 KVRPRPERVITVHGEPQKCLDLATSIHRKF 635 V + +I VHGE L +++ KF Sbjct: 433 LV--NADHIILVHGEQTNMGRLKSALASKF 460 >pir||C72774 probable cleavage and polyadenylation specificity factor subunit APE0181 - Aeropyrum pernix (strain K1) >gi|5103572|dbj|BAA79093.1| (AP000058) 420aa long hypothetical cleavage and polyadenylation specificity factor subunit [Aeropyrum pernix] Length = 420 Score = 203 bits (511), Expect = 5e-51 Identities = 150/465 (32%), Positives = 235/465 (50%), Gaps = 51/465 (10%) Query: 190 RITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGLL 249 RI LG REVGR+A+LV++ +L+D+GVN F D P F ++ L Sbjct: 3 RIRILGSGREVGRAAILVESGGRGLLLDYGVN----------FDENDRPVFPGDVRPRDL 52 Query: 250 DAIIITHAHLDHSGMLPYLFRYNLFDGP-IYTTPPTRDLMVLLQKDFIEIQQSNGQDPLY 308 D +++TH+HLDH G PYL+ + GP ++ T T + LL D I++ NG Y Sbjct: 53 DGLVLTHSHLDHIGAAPYLY---VSQGPKVFGTRVTLHVSRLLLYDMIKL---NGAYLPY 106 Query: 309 RPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAITGDF 368 R +++++ +DYG + T ++ GHI GS V + + I T D Sbjct: 107 DERSVEDMLGTAEYIDYGREYEAGRFAFKTFYS-GHIPGSTAVLVEVDG--RRILYTSDV 163 Query: 369 KFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLI 428 I T+L+ PA + + + +++ESTYG ++ PR +E+R + + +GG VL+ Sbjct: 164 NVIETKLVGPARLEGAKADVVIVESTYGDSD--HPPRSVSEERFYNAVMDVVSQGGTVLV 221 Query: 429 PAMAVGRAQEVMMVLEDYARIGAIDAPIYLDGMIWEATAIHTAYPEYLSRRLREQIFKEG 488 PA +V R QE+ M+L + + P++LDGMI + I+ A P + I G Sbjct: 222 PAFSVSRGQEIAMILAERG----FEYPVWLDGMIRQVAEIYAANPRF--------ILNPG 269 Query: 489 YNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSIIFV 548 + F V+ ++R+ +P +IIAS+GML GGPS+ Y +++A + +N I V Sbjct: 270 LLMKVMSEFRIVSGWQDRRRAF--KKPGVIIASAGMLKGGPSLYYARKMATNKKNGIFMV 327 Query: 549 SYQAEGTLGRQVQSGVREIPMVGEEG--RTEVIKVNMEVHTIDGFSGHADRRELMNYVAK 606 SYQA GT GR M+ EEG E I V V D FS H D+ ++ + Sbjct: 328 SYQAPGTPGR----------MILEEGVFGEERIPVLARVEWFD-FSSHIDQSGIIKLLRS 376 Query: 607 VRPRPERVITVHGEPQKCLDLATSIHRKFGL-STRAPNNLDTIRL 650 V E+V+ VHG+P+ L T I + G+ P N+D + + Sbjct: 377 VN-GVEKVVLVHGDPKAQEALKTRIREELGIREVETPGNMDVLEV 420 >emb|CAA65151.1| (X95906) Cleavage and Polyadenylation Specifity Factor protein [Bos taurus] Length = 684 Score = 202 bits (509), Expect = 9e-51 Identities = 140/479 (29%), Positives = 241/479 (50%), Gaps = 37/479 (7%) Query: 182 PEYKSRWIRITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQ 241 P +S + I LG +EVGRS ++++ +++D G++ + A P+ D Sbjct: 5 PAEESDQLLIRPLGAGQEVGRSCIILEFKGRKIMLDCGIHPGL--EGMDALPYID----- 57 Query: 242 YVLKEGLLDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQS 301 ++ +D ++I+H HLDH G LP+ + F G + T T+ + L D++++ Sbjct: 58 -LIDPAEIDLLLISHFHLDHCGALPWFLQKTSFKGRTFMTHATKAIYRWLLSDYVKVSNI 116 Query: 302 NGQDPLYRPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHN 361 + D LY D++E + T+++ EV++++ I+ ++AGH+LG+A+ + I Sbjct: 117 SADDMLYTETDLEESMDKIETINFHEVKEVA-GIKFWCYHAGHVLGAAMFMIEIAG--VK 173 Query: 362 IAITGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLK 421 + TGDF R L A + + L++ESTYG I REE E R +H + Sbjct: 174 LLYTGDFSRQEDRHLMAAEIPNIKPDILIIESTYG--THIHEKREEREARFCNTVHDIVN 231 Query: 422 RGGKVLIPAMAVGRAQEVMMVLEDY--ARIGAIDAPI-YLDGMIWEATAIHTAYPEYLSR 478 RGG+ LIP A+GRAQE++++L++Y D PI Y + + A++ Y ++ Sbjct: 232 RGGRGLIPVFALGRAQELLLILDEYWQNHPELHDIPIYYASSLAKKCMAVYQTYVNAMND 291 Query: 479 RLREQIFKEGYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLA 538 ++R+QI NPF +F ++N K D D P++++AS GM+ G S E F+ Sbjct: 292 KIRKQI--NINNPF---VFKHISNLKS-MDHFDDIGPSVVMASPGMMQSGLSRELFESWC 345 Query: 539 PDPRNSIIFVSYQAEGTLGRQVQSGVREI-PMVGEEGRTEVIKVNMEVHTIDGFSGHADR 597 D RN +I Y EGTL + + S EI M G++ + + M V I FS H D Sbjct: 346 TDKRNGVIIAGYCVEGTLAKHIMSEPEEITTMSGQK-----LPLKMSVDYI-SFSAHTDY 399 Query: 598 RELMNYVAKVRPRPERVITVHGEPQKCLDLATSIHRKF------GLSTRAPNNLDTIRL 650 ++ ++ + +P VI VHGE + L ++ R++ + P N + + L Sbjct: 400 QQTSEFIRAL--KPPHVILVHGEQNEMARLKAALIREYEDNDEVHIEVHNPRNTEAVTL 456 >gi|7706427 cleavage and polyadenylation specific factor 3, 73kD subunit; cleavage and polyadenylation specificity factor73 kDa subunit; cleavage and polyadenylation specificity factor 73 kDa subunit; cleavage and polyadenylation specificity factor 3, 73kD subunit> >gi|6002955|gb|AAF00224.1|AF171877_1 (AF171877) cleavage and polyadenylation specificity factor 73 kDa subunit [Homo sapiens] Length = 684 Score = 202 bits (509), Expect = 9e-51 Identities = 140/479 (29%), Positives = 241/479 (50%), Gaps = 37/479 (7%) Query: 182 PEYKSRWIRITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQ 241 P +S + I LG +EVGRS ++++ +++D G++ + A P+ D Sbjct: 5 PAEESDQLLIRPLGAGQEVGRSCIILEFKGRKIMLDCGIHPGL--EGMDALPYID----- 57 Query: 242 YVLKEGLLDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQS 301 ++ +D ++I+H HLDH G LP+ + F G + T T+ + L D++++ Sbjct: 58 -LIDPAEIDLLLISHFHLDHCGALPWFLQKTSFKGRTFMTHATKAIYRWLLSDYVKVSNI 116 Query: 302 NGQDPLYRPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHN 361 + D LY D++E + T+++ EV++++ I+ ++AGH+LG+A+ + I Sbjct: 117 SADDMLYTETDLEESMDKIETINFHEVKEVA-GIKFWCYHAGHVLGAAMFMIEIAG--VK 173 Query: 362 IAITGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLK 421 + TGDF R L A + + L++ESTYG I REE E R +H + Sbjct: 174 LLYTGDFSRQEDRHLMAAEIPNIKPDILIIESTYG--THIHEKREEREARFCNTVHDIVN 231 Query: 422 RGGKVLIPAMAVGRAQEVMMVLEDY--ARIGAIDAPI-YLDGMIWEATAIHTAYPEYLSR 478 RGG+ LIP A+GRAQE++++L++Y D PI Y + + A++ Y ++ Sbjct: 232 RGGRGLIPVFALGRAQELLLILDEYWQNHPELHDIPIYYASSLAKKCMAVYQTYVNAMND 291 Query: 479 RLREQIFKEGYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLA 538 ++R+QI NPF +F ++N K D D P++++AS GM+ G S E F+ Sbjct: 292 KIRKQI--NINNPF---VFKHISNLKS-MDHFDDIGPSVVMASPGMMQSGLSRELFESWC 345 Query: 539 PDPRNSIIFVSYQAEGTLGRQVQSGVREI-PMVGEEGRTEVIKVNMEVHTIDGFSGHADR 597 D RN +I Y EGTL + + S EI M G++ + + M V I FS H D Sbjct: 346 TDKRNGVIIAGYCVEGTLAKHIMSEPEEITTMSGQK-----LPLKMSVDYI-SFSAHTDY 399 Query: 598 RELMNYVAKVRPRPERVITVHGEPQKCLDLATSIHRKF------GLSTRAPNNLDTIRL 650 ++ ++ + +P VI VHGE + L ++ R++ + P N + + L Sbjct: 400 QQTSEFIRAL--KPPHVILVHGEQNEMARLKAALIREYEDNDEVHIEVHNPRNTEAVTL 456 >gi|9055194 cleavage and polyadenylation specificity factor 3; 73 kDa [Mus musculus] >gi|6625904|gb|AAF19420.1|AF203969_1 (AF203969) cleavage and polyadenylation specificity factor 73 kDa subunit [Mus musculus] Length = 684 Score = 201 bits (507), Expect = 2e-50 Identities = 140/479 (29%), Positives = 241/479 (50%), Gaps = 37/479 (7%) Query: 182 PEYKSRWIRITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQ 241 P +S + I LG +EVGRS ++++ +++D G++ + A P+ D Sbjct: 5 PAEESDQLLIRPLGAGQEVGRSCIILEFKGRKIMLDCGIHPGL--EGMDALPYID----- 57 Query: 242 YVLKEGLLDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQS 301 ++ +D ++I+H HLDH G LP+ + F G + T T+ + L D++++ Sbjct: 58 -LIDPAEIDLLLISHFHLDHCGALPWFLQKTSFKGRTFMTHATKAIYRWLLSDYVKVSNI 116 Query: 302 NGQDPLYRPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHN 361 + D LY D++E + T+++ EV++++ I+ ++AGH+LG+A+ + I Sbjct: 117 SADDMLYTETDLEESMDKIETINFHEVKEVA-GIKFWCYHAGHVLGAAMFMIEIAG--VK 173 Query: 362 IAITGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLK 421 + TGDF R L A + + L++ESTYG I REE E R +H + Sbjct: 174 LLYTGDFSRQEDRHLMAAEIPNIKPDILIIESTYG--THIHEKREEREARFWHTVHDIVN 231 Query: 422 RGGKVLIPAMAVGRAQEVMMVLEDY--ARIGAIDAPI-YLDGMIWEATAIHTAYPEYLSR 478 RGG+ LIP A+GRAQE++++L++Y D PI Y + + A++ Y ++ Sbjct: 232 RGGRGLIPVFALGRAQELLLILDEYWQNHPELHDIPIYYASSLAKKCMAVYQTYVNAMND 291 Query: 479 RLREQIFKEGYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLA 538 ++R+QI NPF +F ++N K D D P++++AS GM+ G S E F+ Sbjct: 292 KIRKQI--NINNPF---VFKHISNLKS-MDHFDDIGPSVVMASPGMIQNGLSRELFESWC 345 Query: 539 PDPRNSIIFVSYQAEGTLGRQVQSGVREI-PMVGEEGRTEVIKVNMEVHTIDGFSGHADR 597 D RN +I Y EGTL + + S EI M G++ + + M V I FS H D Sbjct: 346 TDKRNGVIIAGYCVEGTLAKHIMSEPEEITTMSGQK-----LPLKMSVDYI-SFSAHTDY 399 Query: 598 RELMNYVAKVRPRPERVITVHGEPQKCLDLATSIHRKF------GLSTRAPNNLDTIRL 650 ++ ++ + +P VI VHGE + L ++ R++ + P N + + L Sbjct: 400 QQTSEFIRAL--KPPHVILVHGEQNEMARLKAALIREYEDNDEVHIEVHNPRNTEAVTL 456 >gb|AAD12712.1| (AC006069) putative cleavage and polyadenylation specifity factor [Arabidopsis thaliana] Length = 837 Score = 201 bits (506), Expect = 2e-50 Identities = 135/462 (29%), Positives = 230/462 (49%), Gaps = 32/462 (6%) Query: 194 LGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGLLD--- 250 LG +E+G+S ++V + ++ D G+++ D + +P+F + K G D Sbjct: 8 LGAGQEIGKSCVVVTINGKKIMFDCGMHMGC--DDHNRYPNFSL-----ISKSGDFDNAI 60 Query: 251 -AIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQ-QSNGQDPLY 308 IIITH H+DH G LPY ++GPIY + PT+ L L+ +D+ + G++ L+ Sbjct: 61 SCIIITHFHMDHVGALPYFTEVCGYNGPIYMSYPTKALSPLMLEDYRRVMVDRRGEEELF 120 Query: 309 RPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAITGDF 368 I +K I +D + + D+++ + AGH+LG+ +V+ +G+ I TGD+ Sbjct: 121 TTTHIANCMKKVIAIDLKQTIQVDEDLQIRAYYAGHVLGAVMVYAKMGDAA--IVYTGDY 178 Query: 369 KFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLI 428 R L A +L+ L+ ESTY A I+ + E+ ++ +H+ + GGK LI Sbjct: 179 NMTTDRHLGAAKIDRLQLDLLISESTY--ATTIRGSKYPREREFLQAVHKCVAGGGKALI 236 Query: 429 PAMAVGRAQEVMMVLEDYARIGAIDAPIYL-DGMIWEATAIHTAYPEYLSRRLREQIFKE 487 P+ A+GRAQE+ M+L+DY I PIY G+ +A + + S+ ++E+ Sbjct: 237 PSFALGRAQELCMLLDDYWERMNIKVPIYFSSGLTIQANMYYKMLISWTSQNVKEK--HN 294 Query: 488 GYNPFLSEIFHPVANSKE-RQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSII 546 +NPF N K+ + +I + P ++ A+ GML G S+E FK AP P N + Sbjct: 295 THNPF------DFKNVKDFDRSLIHAPGPCVLFATPGMLCAGFSLEVFKHWAPSPLNLVA 348 Query: 547 FVSYQAEGTLGRQVQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRRELMNYVAK 606 Y GT+G ++ +G P + + V +VH + FS H D + +M+ Sbjct: 349 LPGYSVAGTVGHKLMAGK---PTTVDLYNGTKVDVRCKVHQV-AFSPHTDAKGIMDLTKF 404 Query: 607 VRPRPERVITVHGEPQKCLDLATSIHRKFGLSTRAPNNLDTI 648 + P+ V+ VHGE + L I + + P N +T+ Sbjct: 405 LSPK--NVVLVHGEKPSMMILKEKITSELDIPCFVPANGETV 444 >gb|AAF55578.1| (AE003723) CG7698 gene product [Drosophila melanogaster] Length = 705 Score = 195 bits (491), Expect = 1e-48 Identities = 133/459 (28%), Positives = 231/459 (49%), Gaps = 29/459 (6%) Query: 180 RKPEYKSRWIRITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPE 239 R P+ +S ++I LG +EVGRS ++++ +++D G+ + DA Sbjct: 9 RMPDEESDLLQIKPLGAGQEVGRSCIMLEFKGKKIMLDCGI--------HPGLSGMDALP 60 Query: 240 FQYVLKEGLLDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQ 299 + +++ +D + I+H HLDH G LP+ F G + T T+ + + D+I+I Sbjct: 61 YVDLIEADEIDLLFISHFHLDHCGALPWFLMKTSFKGRCFMTHATKAIYRWMLSDYIKIS 120 Query: 300 QSNGQDPLYRPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGL 359 + + LY D++ ++ T+++ E RD+ +R + AGH+LG+A+ + I Sbjct: 121 NISTEQMLYTEADLEASMEKIETINFHEERDVM-GVRFCAYIAGHVLGAAMFMIEIAG-- 177 Query: 360 HNIAITGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQT 419 I TGDF R L A + + L+ ESTYG I RE+ E R ++ + Sbjct: 178 IKILYTGDFSRQEDRHLMAAEVPPMKPDVLITESTYG--THIHEKREDRENRFTSLVQKI 235 Query: 420 LKRGGKVLIPAMAVGRAQEVMMVLEDY--ARIGAIDAPI-YLDGMIWEATAIHTAYPEYL 476 +++GG+ LIP A+GRAQE++++L+++ + PI Y + + A++ Y + Sbjct: 236 VQQGGRCLIPVFALGRAQELLLILDEFWSQNPDLHEIPIYYASSLAKKCMAVYQTYINAM 295 Query: 477 SRRLREQIFKEGYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQ 536 + R+R QI NPF +F ++N K D + P +I+AS GM+ G S E F+ Sbjct: 296 NDRIRRQIAVN--NPF---VFRHISNLK-GIDHFEDIGPCVIMASPGMMQSGLSRELFES 349 Query: 537 LAPDPRNSIIFVSYQAEGTLGRQVQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHAD 596 DP+N +I Y EGTL + V S EI + + + +NM V I FS H D Sbjct: 350 WCTDPKNGVIIAGYCVEGTLAKAVLSEPEEITTLS----GQKLPLNMSVDYI-SFSAHTD 404 Query: 597 RRELMNYVAKVRPRPERVITVHGEPQKCLDLATSIHRKF 635 ++ ++ + +P V+ VHGE + L ++ R++ Sbjct: 405 YQQTSEFIRLL--KPTHVVLVHGEQNEMSRLKLALQREY 441 >dbj|BAA33615.1| (AB012956) unknown [Vibrio cholerae] Length = 446 Score = 192 bits (482), Expect = 1e-47 Identities = 142/437 (32%), Positives = 221/437 (50%), Gaps = 35/437 (8%) Query: 195 GGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGLLDAIII 254 GG V S ++ D +L+D G+ A P A EF G +DA+I+ Sbjct: 15 GGKASVTGSCHELRADGQALLIDCGLFQGADERPL-------AVEFAL----GHVDALIL 63 Query: 255 THAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPLYRPRDIK 314 THAH+DH G LP+L F PIY T T +L+ L+ +D +++Q G P R + Sbjct: 64 THAHIDHIGRLPWLLAAG-FKQPIYCTAATAELVPLMLEDGLKLQL--GMSPKQSERVLT 120 Query: 315 EVIKHTITLDYGEVRDISP----DIRLTLHNAGHILGSAIVHLHIGNGLHNIAITGDFKF 370 EV + DY + + P + + AGHILGSA V + NG + +GD Sbjct: 121 EVRRLLRVQDYQKWFAVQPKCADSLWVRFQPAGHILGSAYVEIRRPNG-EVVVFSGDLGP 179 Query: 371 IPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLIPA 430 T LL P R + L +E+TYG + + +RL +I ++L GG +LIPA Sbjct: 180 SHTPLL-PDPQSPERADYLFIETTYGDKQHEDV--QSRGQRLRAMIERSLTDGGAILIPA 236 Query: 431 MAVGRAQEVMMVLEDYARIGAIDA--PIYLDG-MIWEATAIHTAYPEYLSRRLREQIFKE 487 +VGR QE++ +E IDA PI LD M T + + + R + ++ Sbjct: 237 FSVGRTQELLFDIEQLIFSQQIDANLPIILDSPMAQRVTRSYRRFKQLWGREAKARLQMH 296 Query: 488 GYNPFLSEIFHPVANSKERQDIID----SNEPAIIIASSGMLVGGPSVEYFKQLAPDPRN 543 + P E V + + + +++ + E AI++A+SGM GG ++Y K L PD R Sbjct: 297 RH-PLAFEQCITVEDHRTHERLVNRLASTGEAAIVVAASGMCQGGRIMDYLKALLPDKRT 355 Query: 544 SIIFVSYQAEGTLGRQVQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRRELMNY 603 +I +QAEGTLGR +QSG + + G E ++VN +HT+ G+S HAD+ +L+ + Sbjct: 356 DLILAGFQAEGTLGRSIQSGQPSVWIEGTE-----VEVNAHIHTMSGYSAHADKADLLRF 410 Query: 604 VAKVRPRPERVITVHGE 620 +A + +P++V +HGE Sbjct: 411 IAGIPEKPKQVHLIHGE 427 >pir||F82345 conserved hypothetical protein VC0264 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9654673|gb|AAF93439.1| (AE004114) conserved hypothetical protein [Vibrio cholerae] Length = 455 Score = 190 bits (478), Expect = 4e-47 Identities = 141/437 (32%), Positives = 221/437 (50%), Gaps = 35/437 (8%) Query: 195 GGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGLLDAIII 254 GG V S ++ D +L+D G+ A P A EF G +DA+I+ Sbjct: 24 GGKASVTGSCHELRADGQALLIDCGLFQGADERPL-------AVEFAL----GHVDALIL 72 Query: 255 THAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPLYRPRDIK 314 THAH+DH G LP+L L PIY+T T +L+ L+ +D +++Q G P R + Sbjct: 73 THAHIDHIGRLPWLLAAGLKQ-PIYSTAATAELVPLMLEDGLKLQL--GMSPKQSERVLT 129 Query: 315 EVIKHTITLDYGEVRDISP----DIRLTLHNAGHILGSAIVHLHIGNGLHNIAITGDFKF 370 EV + DY + + P + + AGHILGSA V + NG + +GD Sbjct: 130 EVRRLLRVQDYQKWFAVQPKRADSLWVRFQPAGHILGSAYVEIRRPNG-EVVVFSGDLGP 188 Query: 371 IPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLIPA 430 T LL P R + L +E+TYG + + +RL +I ++L GG +LIPA Sbjct: 189 SHTPLL-PDPQSPERADYLFIETTYGDKQHEDV--QSRGQRLRAMIERSLTDGGAILIPA 245 Query: 431 MAVGRAQEVMMVLEDYARIGAIDA--PIYLDG-MIWEATAIHTAYPEYLSRRLREQIFKE 487 +VGR QE++ +E IDA PI LD M T + + + R + ++ Sbjct: 246 FSVGRTQELLFDIEQLIFSQQIDANLPIILDSPMAQRVTRSYRRFKQLWGREAKARLQMH 305 Query: 488 GYNPFLSEIFHPVANSKERQDIID----SNEPAIIIASSGMLVGGPSVEYFKQLAPDPRN 543 + P E V + + + +++ + E AI++A+SGM GG ++Y K L PD R Sbjct: 306 RH-PLAFEQCITVEDHRTHERLVNRLASTGEAAIVVAASGMCQGGRIMDYLKALLPDKRT 364 Query: 544 SIIFVSYQAEGTLGRQVQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRRELMNY 603 +I +QAEGTLGR +QSG + + G E ++VN +HT+ G+S HAD+ +L+ + Sbjct: 365 DLILAGFQAEGTLGRSIQSGQPSVWIEGTE-----VEVNAHIHTMSGYSAHADKADLLRF 419 Query: 604 VAKVRPRPERVITVHGE 620 + + +P++V +HGE Sbjct: 420 ITGIPEKPKQVHLIHGE 436 >gb|AAF27682.1|AC018908_21 (AC018908) putative cleavage and polyadenylation specificity factor; 72745-70039 [Arabidopsis thaliana] Length = 693 Score = 187 bits (470), Expect = 3e-46 Identities = 131/466 (28%), Positives = 233/466 (49%), Gaps = 32/466 (6%) Query: 191 ITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGLLD 250 +T LG EVGRS + + +L D G++ A A P+FD + +D Sbjct: 24 VTPLGAGSEVGRSCVYMSFRGKNILFDCGIHPAYSG--MAALPYFDE------IDPSSID 75 Query: 251 AIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPLYRP 310 ++ITH H+DH+ LPY F+G ++ T T+ + LL D++++ + + +D L+ Sbjct: 76 VLLITHFHIDHAASLPYFLEKTTFNGRVFMTHATKAIYKLLLTDYVKVSKVSVEDMLFDE 135 Query: 311 RDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAITGDFKF 370 +DI + + +D+ + +++ I+ + AGH+LG+A+ + I I TGD+ Sbjct: 136 QDINKSMDKIEVIDFHQTVEVN-GIKFWCYTAGHVLGAAMFMVDIAG--VRILYTGDYSR 192 Query: 371 IPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLIPA 430 R L A + ++EST G + R EKR +VIH T+ +GG+VLIPA Sbjct: 193 EEDRHLRAAELPQFSPDICIIESTSG--VQLHQSRHIREKRFTDVIHSTVAQGGRVLIPA 250 Query: 431 MAVGRAQEVMMVLEDY--ARIGAIDAPI-YLDGMIWEATAIHTAYPEYLSRRLREQIFKE 487 A+GRAQE++++L++Y + PI Y + + A++ Y ++ R+R Q Sbjct: 251 FALGRAQELLLILDEYWANHPDLHNIPIYYASPLAKKCMAVYQTYILSMNDRIRNQFANS 310 Query: 488 GYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSIIF 547 NPF+ + P+ + + D+ P++++A+ G L G S + F D +N+ I Sbjct: 311 --NPFVFKHISPLNSIDDFNDV----GPSVVMATPGGLQSGLSRQLFDSWCSDKKNACII 364 Query: 548 VSYQAEGTLGRQVQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRRELMNYVAKV 607 Y EGTL + + + +E+ ++ G T +NM+VH I FS HAD + ++ ++ Sbjct: 365 PGYMVEGTLAKTIINEPKEVTLM--NGLT--APLNMQVHYI-SFSAHADYAQTSTFLKEL 419 Query: 608 RPRPERVITVHGEPQKCLDLATSIHRKF---GLSTRAPNNLDTIRL 650 P +I VHGE + + L + +F P N +++ + Sbjct: 420 --MPPNIILVHGEANEMMRLKQKLLTEFPDGNTKIMTPKNCESVEM 463 >gi|6323307 Ysh1p [Saccharomyces cerevisiae] >gi|1077401|pir||S51413 probable membrane protein YLR277c - yeast (Saccharomyces cerevisiae) >gi|577190|gb|AAB67367.1| (U17245) Ysh1p: subunit of polyadenylation factor I (PF I) [Saccharomyces cerevisiae] Length = 779 Score = 186 bits (468), Expect = 6e-46 Identities = 127/441 (28%), Positives = 218/441 (48%), Gaps = 36/441 (8%) Query: 194 LGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGLLDAII 253 LGG EVGRS ++Q V++D G++ A + P +D + V D ++ Sbjct: 14 LGGSNEVGRSCHILQYKGKTVMLDAGIHPAYQG--LASLPFYDEFDLSKV------DILL 65 Query: 254 ITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEI--------QQSNGQD 305 I+H HLDH+ LPY+ + F G ++ T PT+ + L +DF+ + + Sbjct: 66 ISHFHLDHAASLPYVMQRTNFQGRVFMTHPTKAIYRWLLRDFVRVTSIGSSSSSMGTKDE 125 Query: 306 PLYRPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAIT 365 L+ D+ + T+DY D++ I+ T +AGH+LG+A+ + I GL + T Sbjct: 126 GLFSDEDLVDSFDKIETVDYHSTVDVN-GIKFTAFHAGHVLGAAMFQIEIA-GLR-VLFT 182 Query: 366 GDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGK 425 GD+ R L A L++EST+G A PR E++L ++IH T+ RGG+ Sbjct: 183 GDYSREVDRHLNSAEVPPLSSNVLIVESTFGTAT--HEPRLNRERKLTQLIHSTVMRGGR 240 Query: 426 VLIPAMAVGRAQEVMMVLEDY-----ARIGAIDAPI-YLDGMIWEATAIHTAYPEYLSRR 479 VL+P A+GRAQE+M++L++Y +G PI Y + + ++ Y ++ Sbjct: 241 VLLPVFALGRAQEIMLILDEYWSQHADELGGGQVPIFYASNLAKKCMSVFQTYVNMMNDD 300 Query: 480 LREQIFKEGYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAP 539 +R++ NPF+ + + N ++ QD P++++AS GML G S + ++ P Sbjct: 301 IRKKFRDSQTNPFIFKNISYLRNLEDFQDF----GPSVMLASPGMLQSGLSRDLLERWCP 356 Query: 540 DPRNSIIFVSYQAEGTLGRQVQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRRE 599 + +N ++ Y EGT+ + + IP + T I +V I F+ H D +E Sbjct: 357 EDKNLVLITGYSIEGTMAKFIMLEPDTIPSINNPEIT--IPRRCQVEEI-SFAAHVDFQE 413 Query: 600 LMNYVAKVRPRPERVITVHGE 620 + ++ K+ +I VHGE Sbjct: 414 NLEFIEKI--SAPNIILVHGE 432 >pir||C83195 hypothetical protein PA3614 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9949771|gb|AAG07002.1|AE004781_10 (AE004781) hypothetical protein [Pseudomonas aeruginosa] Length = 467 Score = 182 bits (456), Expect = 1e-44 Identities = 142/484 (29%), Positives = 226/484 (46%), Gaps = 44/484 (9%) Query: 191 ITGLGGFREVGRSALLVQT-DESYVLVDFGVNVA---ALNDPYKAFPHFDAPEFQYVLKE 246 +T LG +EV S L++T D VL++ G+ A N FP FD Sbjct: 4 LTFLGAAQEVTGSCYLLETLDGVKVLLECGMRQGRREADNGNRAPFP-FDPAS------- 55 Query: 247 GLLDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQ-- 304 +DA++I+HAHLDHSG+LP L F GPI+ T T +L+ L+ D IQ+ + + Sbjct: 56 --IDAVVISHAHLDHSGLLPRLAAEG-FKGPIFATEATCELLELMLLDSAHIQEKDAEWE 112 Query: 305 ------------DPLYRPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVH 352 PLY D + +K + G ++ +R+T HNAGHILGS+IV Sbjct: 113 NRWRNRIGKPSIKPLYTQADTERALKLRRPISLGSTVAVARGVRVTFHNAGHILGSSIVE 172 Query: 353 LHIGNGLH--NIAITGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEK 410 + + + + +GD + L+ A + R + +++ESTYG + + + Sbjct: 173 VQFHDQVQPRRLVFSGDLGNTCSPLMR-APSPLSRADVVMLESTYGDRD--HRDSNDTLE 229 Query: 411 RLIEVIHQTLKRGGKVLIPAMAVGRAQEVMMVLEDYARIGAI-DAPIYLDG-MIWEATAI 468 L ++ Q + GG VLIP+ AVGR Q+++ L + + G + ++LD M A I Sbjct: 230 ELAAILDQAHRDGGNVLIPSFAVGRTQDLLYYLGRFYQEGRLPQQAVFLDSPMAARANGI 289 Query: 469 HTAYPEYLSRRLREQIFKEGYNPFLS--EIFHPVANSKERQDIIDSNEPAIIIASSGMLV 526 + + R RE I G + ++ E I A+IIA SGM Sbjct: 290 YLRHSNEFDDRDREYIRGTGTTRLEEWLPVLRVTRSADESMAINRIKSGAVIIAGSGMCT 349 Query: 527 GGPSVEYFKQLAPDPRNSIIFVSYQAEGTLGRQVQSGVREIPMVGEEGRTEVIKVNMEVH 586 GG V +FK P ++F +QA GTLGR + G + + + I V ++H Sbjct: 350 GGRIVHHFKHNLWRPECHVVFPGFQARGTLGRNIVDGASAVRVFHQR-----IAVKAQIH 404 Query: 587 TIDGFSGHADRRELMNYVAKVRPRPERVITVHGEPQKCLDLATSIHRKFGLSTRAPNNLD 646 T+ GFS HA + +L+++V RP + +HGE +K L ++I + P + Sbjct: 405 TLGGFSAHAGQSQLLDWVGHFAHRP-ALYLIHGEREKMEALQSAIRERLDWDAEIPEPGE 463 Query: 647 TIRL 650 I + Sbjct: 464 RIEI 467 >gb|AAG20574.1| (AE005128) mRNA 3'-end processing factor homolog; Epf1 [Halobacterium sp. NRC-1] Length = 410 Score = 181 bits (455), Expect = 2e-44 Identities = 150/455 (32%), Positives = 215/455 (46%), Gaps = 54/455 (11%) Query: 194 LGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGLLDAII 253 LGG REVGRSALLV +L+DFG D P Q+ + DA++ Sbjct: 6 LGGAREVGRSALLVGES---LLLDFGTKA-------------DTPP-QFPVSTPTPDAVV 48 Query: 254 ITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPLYRPRDI 313 +H HLDH G +P L PI+ TPPT +L + L +D +++ P DI Sbjct: 49 ASHGHLDHVGTIPALLS-GTHRPPIHWTPPTYELALTLARDTLKLHGGTYHCPFIE-NDI 106 Query: 314 KEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAITGDFKFIPT 373 K V + + T YG D + +T +NAGH+ GSA H+ + +G + TGDF Sbjct: 107 KRVTEVSRTHGYGVPFDAA-GYEVTFYNAGHVPGSA--HVLVDDGDTRLLYTGDFHTTDQ 163 Query: 374 RLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLIPAMAV 433 RL+ A+ P + +V ESTY R+ E R E + TL GG V++PA A+ Sbjct: 164 RLVSGTTAR-PEADVVVCESTYSDVTHDD--RDSVEARFAESVKTTLWEGGTVVVPAFAI 220 Query: 434 GRAQEVMMVLEDYARIGAIDAPIYLDGMIWEATAIHTAYPEYLSRRLREQIFKEGYNPFL 493 GR QE+++V + A D P Y+DGM T + YP ++ + Sbjct: 221 GRTQELLLVCD------AHDIPCYVDGMGKRVTEMLLRYPGFVRDG-------DALRRAK 267 Query: 494 SEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSIIFVSYQAE 553 S +R+ I D + A I+ +SGML GGP++ Y ++ +P N I YQ Sbjct: 268 SHARFVTGRDGQRKRIAD--QQAAIVTTSGMLSGGPAMTYIPEIRSNPVNKIAMTGYQVA 325 Query: 554 GTLGRQ-VQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRRELMNYVAKVRPRPE 612 GT GR + SG EI +GR V+ V+ +V D FS HAD L ++ R Sbjct: 326 GTPGRSLIDSGRAEI-----DGR--VLPVSAQVEQYD-FSAHADHAGLRAFLDDY--RDA 375 Query: 613 RVITVHGEPQKCLDLATSIHRKFGLSTRAPNNLDT 647 V+ HG+ C A ++ R G + RAP DT Sbjct: 376 TVLVNHGD--DCAAFADAL-RDAGFTARAPERDDT 407 >pir||G75600 cleavage and polyadenylation specificity factor-related protein - Deinococcus radiodurans (strain R1) >gi|6460540|gb|AAF12246.1|AE001862_72 (AE001862) cleavage and polyadenylation specificity factor-related protein [Deinococcus radiodurans] Length = 499 Score = 170 bits (427), Expect = 4e-41 Identities = 126/391 (32%), Positives = 202/391 (51%), Gaps = 34/391 (8%) Query: 249 LDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLM--VLLQKDFIEIQ------- 299 LDA+++THAHLDH G LP L R + GP+Y TPPT L VLL ++++ Sbjct: 67 LDAVLLTHAHLDHVGRLPLLVRLG-YRGPVYCTPPTAALAETVLLDSARLQVEGYRQDLR 125 Query: 300 --QSNGQD-----PLYRPRDIKEVIKHTIT-LDYGEVRDISPDIRLTLHNAGHILGSAIV 351 + G++ PLY D+ + L++GE ++ +R+T AGHILGSA + Sbjct: 126 RARRQGREDEVPPPLYDEEDVHRTLALLRPQLEFGETVTVA-GVRVTPQRAGHILGSAYL 184 Query: 352 HLHIGNGLHNIAITGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKR 411 L G + ++GD + L P ++ +V+E+TY AN E Sbjct: 185 LLEAPEG--RLLMSGDLGNRESGLQLDFTPP-PAVDAVVIETTY--ANRTHRGWVETRAE 239 Query: 412 LIEVIHQTLKRGGKVLIPAMAVGRAQEVMMVLEDYARIGAIDA-PIYLDG-MIWEATAIH 469 + + ++++ GK+LIP+ A+ RAQ ++ L++ G + P++LD M AT + Sbjct: 240 FAQALRDSVRQNGKILIPSFAIERAQTILHTLKEMMDSGEVPRIPVFLDSPMAARATNEY 299 Query: 470 TAYPEYLSRRLREQIFKEGYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGP 529 Y + L +RE + + G +PF H V S E Q + + PAII+A +GM+ GG Sbjct: 300 FEYGDELIPPVREAL-RNGEDPFRPSTLHTVTTSAESQRLNRYDGPAIIMAGNGMMTGGR 358 Query: 530 SVEYFKQLAPDPRNSIIFVSYQAEGTLGRQVQSGVREIPMVGEEGRTEVIKVNMEVHTID 589 + K P S+I VSYQ+ +LG ++ +G + ++GE+ + V +VHTI Sbjct: 359 IQHHLKHHLWKPSTSLIIVSYQSPSSLGGRIVAGQGTVHLMGED-----VAVRAQVHTIG 413 Query: 590 GFSGHADRRELMNYVAKVRPRPERVITVHGE 620 GFS HAD+ +L+ ++ +P V VHGE Sbjct: 414 GFSAHADQDDLLAFL-DTAGKP-HVWLVHGE 442 >emb|CAC11477.1| (AL445064) conserved hypothetical protein [Thermoplasma acidophilum] Length = 407 Score = 164 bits (412), Expect = 2e-39 Identities = 131/440 (29%), Positives = 218/440 (48%), Gaps = 56/440 (12%) Query: 189 IRITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEF--QYVLKE 246 +++ LGG EVGR + + ++ V+VD+GV PE QY L Sbjct: 1 MKLKFLGGAEEVGRLGVKITDKDTSVIVDYGV----------------IPEKPPQYPLPP 44 Query: 247 GLLDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDP 306 +DA+ ITH+HLDH G +P Y+ + +Y T T + M L +D +++ G Sbjct: 45 EPVDAMFITHSHLDHIGAVPVY--YHKGEPDLYATQMTLNTMKPLLRDALKVTNIEGYPA 102 Query: 307 LYRPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAITG 366 ++ DI + + Y E ++ ++ T + AGHI GS + G ++ +TG Sbjct: 103 MFNEDDINSALANMRPARYFESIEVG-NMVATPYPAGHIPGSTMWKFEDGI---SVTVTG 158 Query: 367 DFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKV 426 D I T L+ AK + + L++ESTY G N RE+ KR + + + + GGKV Sbjct: 159 DVNTIDTYLIN--GAKPIKTDVLIIESTYAGKN--HESREDVRKRFRDSVKEVIDSGGKV 214 Query: 427 LIPAMAVGRAQEVMMVLEDYARIGAIDAPIYLDGMIWEATAIHTAYPEYLSRRLREQIFK 486 ++PA AVGR QE++M + D + + +DGM + + I+ P +L K Sbjct: 215 IMPAFAVGRTQELIMTIAD------MGYDVAVDGMGNDISTIYLNTPGFLRS-------K 261 Query: 487 EGYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSII 546 + + LS++ + R++ I S+ III++SGML GGP + Y ++L D +++I Sbjct: 262 KEFLRALSKV-RIIKGRNMRENAIRSD---IIISTSGMLDGGPVLGYIQKLLEDEKSAIF 317 Query: 547 FVSYQAEGTLGRQ-VQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADRRELMNYVA 605 YQ EGT GR +++G I V +K M V D S HA EL+N++ Sbjct: 318 VTGYQVEGTNGRSLLETGTLTIAGV-------TVKPKMRVEFFD-MSAHAGHDELVNFIK 369 Query: 606 KVRPRPERVITVHGEPQKCL 625 + P+ +++ HG+ ++ L Sbjct: 370 AIDPK--KIVLCHGDHRENL 387 >pir||T18488 hypothetical protein C0825c - malaria parasite (Plasmodium falciparum) >gi|3758842|emb|CAB11127.1| (Z98551) putative cleavage and polyadenylation specificity factor protein [Plasmodium falciparum] Length = 1017 Score = 156 bits (390), Expect = 8e-37 Identities = 121/431 (28%), Positives = 200/431 (46%), Gaps = 60/431 (13%) Query: 248 LLDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQ--- 304 ++D +II+H H+DH G LP+ + G I + PT+ L +L D + + Sbjct: 169 IIDCVIISHFHMDHIGALPFFTEILKYRGIILMSYPTKALSPILLLDSCRVTDMKWEKKN 228 Query: 305 -------------------------DPLYRPRD-IKEVIKHTITLDYGEVRDISPDIRLT 338 DP D I I I L E ++ D+ +T Sbjct: 229 FERQIKMLNEKSDELLNYNINCIKKDPWNINEDNIYNCIDKVIGLQINETFELG-DMSIT 287 Query: 339 LHNAGHILGSAIVHLHIGNGLHNIAITGDFKFIPTRLLEPANAKFPRLETLVMESTYGGA 398 + AGH+LG+ I + + N ++ TGD+ IP + L AN E + ESTY A Sbjct: 288 PYYAGHVLGACIYKIEVRN--FSVIYTGDYNTIPDKHLGSANIPSLNPEIFISESTY--A 343 Query: 399 NDIQMPREEAEKRLIEVIHQTLKRGGKVLIPAMAVGRAQEVMMVLEDYARIGAIDAPIYL 458 ++ ++ +E L ++H+ + +GGKVLIP A+GRAQE+ ++L+DY + I PIY Sbjct: 344 TYVRPTKKASELELCNLVHECVHKGGKVLIPVFAIGRAQELSILLDDYWKKMKIHYPIYF 403 Query: 459 D-GMIWEATAIHTAYPEYLSRRL----REQIFK-EGYNPFLSEIFHPVANSKERQDIIDS 512 G+ A + Y +++ +E +F +PFL+ + ++ Sbjct: 404 GCGLTENANKYYKIYSSWINSSCMSNEKENLFDFANISPFLN-------------NYLNE 450 Query: 513 NEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSIIFVSYQAEGTLGRQVQSGVREIPMVGE 572 P ++ A+ GML G S++ FK A +P+N I+ Y +GT+G ++ G ++I + G Sbjct: 451 KRPMVLFATPGMLHTGLSLKAFKAWAGNPQNLIVLPGYCVQGTVGHKLIMGEKQISLDG- 509 Query: 573 EGRTEVIKVNMEVHTIDGFSGHADRRELMNYVAKVRPRPERVITVHGEPQKCLDLATSIH 632 T IKV ++ + FS HAD + + V P+ VI VHGE LA I Sbjct: 510 ---TTYIKVLCKIIYL-SFSAHADSNGIQQLIKHVSPK--NVIFVHGEKNGMQKLAKYIS 563 Query: 633 RKFGLSTRAPN 643 K +++ P+ Sbjct: 564 NKHMINSMCPS 574 >gb|AAB70268.1| (AF017269) 73 kDA subunit of cleavage and polyadenylation specificity factor [Homo sapiens] Length = 379 Score = 152 bits (381), Expect = 9e-36 Identities = 109/356 (30%), Positives = 180/356 (49%), Gaps = 29/356 (8%) Query: 305 DPLYRPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAI 364 D LY D++E + T+++ EV++++ I+ ++AGH+LG+A+ + I + Sbjct: 1 DMLYTETDLEESMDKIETINFHEVKEVA-GIKFWCYHAGHVLGAAMFMIEIAGV--KLLY 57 Query: 365 TGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGG 424 TGDF R L A + + L++ESTYG I REE E R +H + RGG Sbjct: 58 TGDFSRQEDRHLMAAEIPNIKPDILIIESTYG--THIHEKREEREARFCNTVHDIVNRGG 115 Query: 425 KVLIPAMAVGRAQEVMMVLEDY--ARIGAIDAPI-YLDGMIWEATAIHTAYPEYLSRRLR 481 + LIP A+GRAQE++++L++Y D PI Y + + A++ Y ++ ++R Sbjct: 116 RGLIPVFALGRAQELLLILDEYWQNHPELXDXPIYYASSLAKKCMAVYQTYVNAMNDKIR 175 Query: 482 EQIFKEGYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDP 541 +QI NPF +F ++N K D D P++++AS GM+ G S E F+ D Sbjct: 176 KQI--NINNPF---VFKHISNLKS-MDHFDDIGPSVVMASPGMMQSGLSRELFESWCTDK 229 Query: 542 RNSIIFVSYQAEGTLGRQVQSGVREI-PMVGEEGRTEVIKVNMEVHTIDGFSGHADRREL 600 RN +I Y EGTL + + S EI M G++ + + M V I FS H D ++ Sbjct: 230 RNGVIIAGYCVEGTLAKHIMSEPEEITTMSGQK-----LPLKMSVDYI-SFSAHTDYQQT 283 Query: 601 MNYVAKVRPRPERVITVHGEPQKCLDLATSIHRKF------GLSTRAPNNLDTIRL 650 ++ + +P VI VHGE + L ++ R++ + P N + + L Sbjct: 284 SEFIRAL--KPPHVILVHGEQNEMARLKAALIREYEDNDEVHIEVHNPRNTEAVTL 337 >dbj|BAB13943.1| (AK021939) unnamed protein product [Homo sapiens] Length = 499 Score = 151 bits (377), Expect = 3e-35 Identities = 98/322 (30%), Positives = 175/322 (53%), Gaps = 19/322 (5%) Query: 330 DISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAITGDFKFIPTRLLEPANAKFPRLETL 389 D+ ++ + + AGH+LG+A+ + +G+ ++ TGD+ P R L A R L Sbjct: 42 DVDDELEIKAYYAGHVLGAAMFQIKVGS--ESVVYTGDYNMTPDRHLGAAWIDKCRPNLL 99 Query: 390 VMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLIPAMAVGRAQEVMMVLEDYARI 449 + ESTY A I+ + E+ ++ +H+T++RGGKVLIP A+GRAQE+ ++L+ + Sbjct: 100 ITESTY--ATTIRDSKRCRERDFLKKVHETVERGGKVLIPVFALGRAQELCILLKTFWER 157 Query: 450 GAIDAPIYLD-GMIWEATAIHTAYPEYLSRRLREQIFKEGYNPFLSEIFHPVANSKERQD 508 + PIY G+ +A + + + ++++R+ + + E H A + Sbjct: 158 MNLKVPIYFSTGLTEKANHYYKLFIPWTNQKIRKTFVQRN----MFEFKHIKAFDRA--- 210 Query: 509 IIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSIIFVSYQAEGTLGRQVQSGVREIP 568 D+ P ++ A+ GML G S++ F++ A + +N +I Y +GT+G ++ SG R++ Sbjct: 211 FADNPGPMVVFATPGMLHAGQSLQIFRKWAGNEKNMVIMPGYCVQGTVGHKILSGQRKLE 270 Query: 569 MVGEEGRTEVIKVNMEVHTIDGFSGHADRRELMNYVAKVRPRPERVITVHGEPQKCLDLA 628 M EGR +V++V M+V + FS HAD + +M V + PE V+ VHGE +K L Sbjct: 271 M---EGR-QVLEVKMQVEYM-SFSAHADAKGIMQLVGQA--EPESVLLVHGEAKKMEFLK 323 Query: 629 TSIHRKFGLSTRAPNNLDTIRL 650 I ++ ++ P N +T+ L Sbjct: 324 QKIEQELRVNCYMPANGETVTL 345 >gb|AAD54657.1|AF090685_1 (AF090685) hypothetical protein [Vibrio cholerae] Length = 339 Score = 149 bits (373), Expect = 8e-35 Identities = 105/329 (31%), Positives = 167/329 (49%), Gaps = 21/329 (6%) Query: 303 GQDPLYRPRDIKEVIKHTITLDYGEVRDISP----DIRLTLHNAGHILGSAIVHLHIGNG 358 G P R + EV + DY + + P + + AGHILGSA V + NG Sbjct: 2 GMSPKQSERVLTEVRRLLRVQDYQKWFAVQPKCADSLWVRFQPAGHILGSAYVEIRRPNG 61 Query: 359 LHNIAITGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQ 418 + +GD T LL P R + L +E+TYG + + +RL +I + Sbjct: 62 -EVVVFSGDLGPSHTPLL-PDPQSPERADYLFIETTYGDKQHEDV--QSRGQRLRAMIER 117 Query: 419 TLKRGGKVLIPAMAVGRAQEVMMVLEDYARIGAIDA--PIYLDG-MIWEATAIHTAYPEY 475 +L GG +LIPA +VGR QE++ +E IDA PI LD M T + + + Sbjct: 118 SLTDGGAILIPAFSVGRTQELLFDIEQLIFSQQIDANLPIILDSPMAQRVTRSYRRFKQL 177 Query: 476 LSRRLREQIFKEGYNPFLSEIFHPVANSKERQDIID----SNEPAIIIASSGMLVGGPSV 531 R + ++ + P E V + + + +++ + E AI++A+SGM GG + Sbjct: 178 WGREAKARLQMHRH-PLAFEQCITVEDHRTHERLVNRLASTGEAAIVVAASGMCQGGRIM 236 Query: 532 EYFKQLAPDPRNSIIFVSYQAEGTLGRQVQSGVREIPMVGEEGRTEVIKVNMEVHTIDGF 591 +Y K L PD R +I +QAEGTLGR +QSG + + G E ++VN +HT+ G+ Sbjct: 237 DYLKALLPDKRTDLILAGFQAEGTLGRSIQSGQPSVWIEGTE-----VEVNAHIHTMSGY 291 Query: 592 SGHADRRELMNYVAKVRPRPERVITVHGE 620 S HAD+ +L+ ++A + +P++V +HGE Sbjct: 292 SAHADKADLLRFIAGIPEKPKQVHLIHGE 320 >dbj|BAB14541.1| (AK023356) unnamed protein product [Homo sapiens] Length = 278 Score = 123 bits (307), Expect = 4e-27 Identities = 86/259 (33%), Positives = 129/259 (49%), Gaps = 46/259 (17%) Query: 189 IRITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEG- 247 IR+T LG ++VGRS +LV V++D G+++ +D + FP +F Y+ + G Sbjct: 4 IRVTPLGAGQDVGRSCILVSIAGKNVMLDCGMHMGFNDD--RRFP-----DFSYITQNGR 56 Query: 248 ---LLDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQ-QSNG 303 LD +II+H HLDH G LPY +DGPIY T PT+ + +L +D+ +I G Sbjct: 57 LTDFLDCVIISHFHLDHCGALPYFSEMVGYDGPIYMTHPTQAICPILLEDYRKIAVDKKG 116 Query: 304 QDPLYRPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLH----IGNGL 359 + + + IK+ +K + VHLH I G Sbjct: 117 EANFFTSQMIKDCMKKVVA----------------------------VHLHQTVQIKVGS 148 Query: 360 HNIAITGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQT 419 ++ TGD+ P R L A R L+ ESTY A I+ + E+ ++ +H+T Sbjct: 149 ESVVYTGDYNMTPDRHLGAAWIDKCRPNLLITESTY--ATTIRDSKRCRERDFLKKVHET 206 Query: 420 LKRGGKVLIPAMAVGRAQE 438 ++RGGKVLIP A+GRAQE Sbjct: 207 VERGGKVLIPVFALGRAQE 225 >emb|CAB61133.1| (AL132951) predicted using Genefinder; preliminary prediction [Caenorhabditis elegans] Length = 1252 Score = 112 bits (278), Expect = 1e-23 Identities = 79/267 (29%), Positives = 134/267 (49%), Gaps = 23/267 (8%) Query: 393 STYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLIPAMAVGRAQEVMMVLEDY--ARIG 450 STYG R EKR +++H + RGG+ LIPA A+G AQE+M++L++Y + Sbjct: 1 STYG--TQTHEDRAVREKRFTQMVHDIVTRGGRCLIPAFAIGPAQELMLILDEYWESHQE 58 Query: 451 AIDAPI-YLDGMIWEATAIHTAYPEYLSRRLREQIFKEGYNPFLSEIFHPVANSKERQDI 509 D P+ Y + + +++ + ++ R+++QI + NPF IF V+ + Sbjct: 59 LHDIPVYYASSLAKKCMSVYQTFVNGMNSRIQKQIAVK--NPF---IFKHVSTLRGMDQF 113 Query: 510 IDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSIIFVSYQAEGTLGRQVQSGVREIPM 569 D+ P +++A+ GML G S E F+ PD +N I Y EGTL + + S EI Sbjct: 114 EDAG-PCVVLATPGMLQSGFSRELFESWCPDTKNGCIIAGYCVEGTLAKHILSEPEEIVS 172 Query: 570 VGEEGRTEVIKVNMEVHTIDGFSGHADRRELMNYVAKVRPRPERVITVHGEPQKCLDLAT 629 + E + + M+V + FS H D + N+V + +P ++ VHGE + L + Sbjct: 173 LS----GEKLPMRMQVGYV-SFSAHTDYHQTSNFVKAL--KPPHLVLVHGELHEMSRLKS 225 Query: 630 SIHRKF-----GLSTRAPNNLDTIRLR 651 I R+F + P N + ++L+ Sbjct: 226 GIERQFQDDNIPIEVHNPRNTERLQLQ 252 >gb|AAF82809.1|AF283277_1 (AF283277) polyadenylation cleavage/specificity factor 100 kDa subunit [Arabidopsis thaliana] Length = 739 Score = 105 bits (259), Expect = 2e-21 Identities = 97/400 (24%), Positives = 166/400 (41%), Gaps = 30/400 (7%) Query: 189 IRITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGL 248 +++T L G + LV D L+D G N + P + Sbjct: 5 VQVTPLCGVYNENPLSYLVSIDGFNFLIDCGWNDLFDTSLLEPLPRVAST---------- 54 Query: 249 LDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKD-FIEIQQSNGQDPL 307 +DA++++H H G LPY + P+Y T P L +L D F+ +Q + D L Sbjct: 55 IDAVLLSHPDTLHIGALPYAMKQLGLSAPVYATEPVHRLGLLTMYDQFLSRKQVSDFD-L 113 Query: 308 YRPRDIKEVIKHTITLDYGEVRDIS---PDIRLTLHNAGHILGSAIVHLHIGNGLHNIAI 364 + DI ++ I L Y + +S I + H AGH+LG +I I ++ Sbjct: 114 FTLDDIDSAFQNVIRLTYSQNYHLSGKGEGIVIAPHVAGHMLGGSI--WRITKDGEDVIY 171 Query: 365 TGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGG 424 D+ R L + +++ Y Q R++ +K ++ I + L+ GG Sbjct: 172 AVDYNHRKERHLNGTVLQSFVRPAVLITDAYHALYTNQTARQQRDKEFLDTISKHLEVGG 231 Query: 425 KVLIPAMAVGRAQEVMMVLEDYARIGAIDAPIYLDGMIWEATAIHT-AYPEYLSRRLREQ 483 VL+P GR E++++LE + PIY + +T + ++ E++S + + Sbjct: 232 NVLLPVDTAGRVLELLLILEQHWSQRGFSFPIYFLTYVSSSTIDYVKSFLEWMSDSISKS 291 Query: 484 IFKEGYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRN 543 N FL + N + + P +++AS L G + E F + A DPRN Sbjct: 292 FETSRDNAFLLRHVTLLINKTDLDNAPPG--PKVVLASMASLEAGFAREIFVEWANDPRN 349 Query: 544 SIIFVSYQAEGTLGRQVQSG----------VREIPMVGEE 573 ++F GTL R +QS + +P+ GEE Sbjct: 350 LVLFTETGQFGTLARMLQSAPPPKFVKVTMSKRVPLAGEE 389 >dbj|BAB10061.1| (AB005244) cleavage and polyadenylation specificity factor [Arabidopsis thaliana] Length = 739 Score = 104 bits (258), Expect = 2e-21 Identities = 98/401 (24%), Positives = 168/401 (41%), Gaps = 32/401 (7%) Query: 189 IRITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLK-EG 247 +++T L G + LV D L+D G N FD + + + Sbjct: 5 VQVTPLCGVYNENPLSYLVSIDGFNFLIDCGWNDL-----------FDTSLLEPLSRVAS 53 Query: 248 LLDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKD-FIEIQQSNGQDP 306 +DA++++H H G LPY + P+Y T P L +L D F+ +Q + D Sbjct: 54 TIDAVLLSHPDTLHIGALPYAMKQLGLSAPVYATEPVHRLGLLTMYDQFLSRKQVSDFD- 112 Query: 307 LYRPRDIKEVIKHTITLDYGEVRDIS---PDIRLTLHNAGHILGSAIVHLHIGNGLHNIA 363 L+ DI ++ I L Y + +S I + H AGH+LG +I I ++ Sbjct: 113 LFTLDDIDSAFQNVIRLTYSQNYHLSGKGEGIVIAPHVAGHMLGGSI--WRITKDGEDVI 170 Query: 364 ITGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRG 423 D+ R L + +++ Y Q R++ +K ++ I + L+ G Sbjct: 171 YAVDYNHRKERHLNGTVLQSFVRPAVLITDAYHALYTNQTARQQRDKEFLDTISKHLEVG 230 Query: 424 GKVLIPAMAVGRAQEVMMVLEDYARIGAIDAPIYLDGMIWEATAIHT-AYPEYLSRRLRE 482 G VL+P GR E++++LE + PIY + +T + ++ E++S + + Sbjct: 231 GNVLLPVDTAGRVLELLLILEQHWSQRGFSFPIYFLTYVSSSTIDYVKSFLEWMSDSISK 290 Query: 483 QIFKEGYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPR 542 N FL + N + + P +++AS L G + E F + A DPR Sbjct: 291 SFETSRDNAFLLRHVTLLINKTDLDNAPPG--PKVVLASMASLEAGFAREIFVEWANDPR 348 Query: 543 NSIIFVSYQAEGTLGRQVQSG----------VREIPMVGEE 573 N ++F GTL R +QS + +P+ GEE Sbjct: 349 NLVLFTETGQFGTLARMLQSAPPPKFVKVTMSKRVPLAGEE 389 >sp|Q10568|CPSB_BOVIN CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR, 100 KD SUBUNIT (CPSF 100 KD SUBUNIT) >gi|1363022|pir||A56351 cleavage and polyadenylation specificity factor 100K chain - bovine >gi|599683|emb|CAA53535.1| (X75931) Cleavage and Polyadenylation specificity factor (CPSF) 100kD subunit [Bos taurus] Length = 782 Score = 85.0 bits (207), Expect = 2e-15 Identities = 86/378 (22%), Positives = 155/378 (40%), Gaps = 24/378 (6%) Query: 189 IRITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKE-G 247 I++T L G +E L+Q DE L+D G + HF + K Sbjct: 5 IKLTTLSGVQEESALCYLLQVDEFRFLLDCGWD-----------EHFSMDIIDSLRKHVH 53 Query: 248 LLDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPL 307 +DA++++H H G LPY + IY T P + + D + + + L Sbjct: 54 QIDAVLLSHPDPLHLGALPYAVGKLGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDFTL 113 Query: 308 YRPRDIKEVIKHTITLDYGEVRDISPD---IRLTLHNAGHILGSAIVHLHIGNGLHNIAI 364 + D+ L + ++ ++ + +T AGH++G I + + +G I Sbjct: 114 FTLDDVDAAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIGGTIWKI-VKDGEEEIVY 172 Query: 365 TGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGG 424 DF L + + +L++ ++ A +Q R++ +++L+ + +TL+ G Sbjct: 173 AVDFNHKREIHLNGCSLEMLSRPSLLITDSFN-ATYVQPRRKQRDEQLLTNVLETLRGDG 231 Query: 425 KVLIPAMAVGRAQEVMMVLEDYARIGAIDAPIY----LDGMIWEATAIHTAYPEYLSRRL 480 VLI GR E+ +L+ R +Y L+ + + + E++S +L Sbjct: 232 NVLIAVDTAGRVLELAQLLDQIWRTKDAGLGVYSLALLNNVSYNVVEFSKSQVEWMSDKL 291 Query: 481 REQIFKEGYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPD 540 + NPF F ++ D+ P +++AS L G S + F Q D Sbjct: 292 MRCFEDKRNNPFQ---FRHLSLCHGLSDLARVPSPKVVLASQPDLECGFSRDLFIQWCQD 348 Query: 541 PRNSIIFVSYQAEGTLGR 558 P+NSII GTL R Sbjct: 349 PKNSIILTYRTTPGTLAR 366 >gi|8393762 cleavage and polyadenylation specific factor 2, 100kD subunit; cleavage and polyadenylation specificity factor [Mus musculus] >gi|2331036|gb|AAB66830.1| (AF012822) cleavage and polyadenylation specificity factor [Mus musculus] Length = 782 Score = 83.9 bits (204), Expect = 5e-15 Identities = 85/378 (22%), Positives = 155/378 (40%), Gaps = 24/378 (6%) Query: 189 IRITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKE-G 247 I++T L G +E L+Q DE L+D G + HF + K Sbjct: 5 IKLTTLSGVQEESALCYLLQVDEFRFLLDCGWD-----------EHFSVDIIDSLRKHVH 53 Query: 248 LLDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPL 307 +DA++++H H G LP+ + IY T P + + D + + + L Sbjct: 54 QIDAVLLSHPDPLHLGALPFAVGKLGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDFTL 113 Query: 308 YRPRDIKEVIKHTITLDYGEVRDISPD---IRLTLHNAGHILGSAIVHLHIGNGLHNIAI 364 + D+ L + ++ ++ + +T AGH++G I + + +G I Sbjct: 114 FTLDDVDAAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIGGTIWKI-VKDGEEEIVY 172 Query: 365 TGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGG 424 DF L + + +L++ ++ A +Q R++ +++L+ + +TL+ G Sbjct: 173 AVDFNHKREIHLNGCSLEMLSRPSLLITDSFN-ATYVQPRRKQRDEQLLTNVLETLRGDG 231 Query: 425 KVLIPAMAVGRAQEVMMVLEDYARIGAIDAPIY----LDGMIWEATAIHTAYPEYLSRRL 480 VLI GR E+ +L+ R +Y L+ + + + E++S +L Sbjct: 232 NVLIAVDTAGRVLELAQLLDQIWRTKDAGLGVYSLALLNNVSYNVVEFSKSQVEWMSDKL 291 Query: 481 REQIFKEGYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPD 540 + NPF F ++ D+ P +++AS L G S + F Q D Sbjct: 292 MRCFEDKRNNPFQ---FRHLSLCHGLSDLARVPSPKVVLASQPDLECGFSRDLFIQWCQD 348 Query: 541 PRNSIIFVSYQAEGTLGR 558 P+NSII GTL R Sbjct: 349 PKNSIILTYRTTPGTLAR 366 >gb|AAD33061.1|AF139986_1 (AF139986) cleavage and polyadenylation specificity factor 100 kDa subunit [Xenopus laevis] Length = 783 Score = 83.1 bits (202), Expect = 9e-15 Identities = 87/380 (22%), Positives = 154/380 (39%), Gaps = 28/380 (7%) Query: 189 IRITGLGGFREVGRSALLVQTDESYVLVDFGVNV---AALNDPYKAFPHFDAPEFQYVLK 245 I++T L G +E L+Q DE L+D G + + D K + H Sbjct: 5 IKLTTLVGAQEESAVCYLLQVDEFRFLLDCGWDENFSMDIIDSVKKYVH----------- 53 Query: 246 EGLLDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQD 305 +DA++++H H G LPY + IY T P + + D + + + Sbjct: 54 --QVDAVLLSHPDPLHLGALPYAVGKLGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDF 111 Query: 306 PLYRPRDIKEVIKHTITLDYGEVRDISPD---IRLTLHNAGHILGSAIVHLHIGNGLHNI 362 L+ D+ L Y ++ + + +T AGH++G I + + +G I Sbjct: 112 SLFSLDDVDCAFDKIQQLKYNQIVHLKGKGHGLSITPLPAGHMIGGTIWKI-VKDGEEEI 170 Query: 363 AITGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKR 422 DF L + + +L++ ++ A +Q R++ +++L+ + +TL+ Sbjct: 171 VYAVDFNHKREIHLNGCSLEMINRPSLLITDSFN-ATYVQPRRKQRDEQLLTNVLETLRG 229 Query: 423 GGKVLIPAMAVGRAQEVMMVLEDYARIGAIDAPIY----LDGMIWEATAIHTAYPEYLSR 478 G VLI GR E+ +L+ R +Y L+ + + + E++S Sbjct: 230 DGNVLIAVDTAGRVLELAQLLDQIWRTKDAGLGVYSLALLNNVSYNVVEFSKSQVEWMSD 289 Query: 479 RLREQIFKEGYNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLA 538 +L + NPF F + D+ P +++AS L G S E F Q Sbjct: 290 KLMRCFEDKRNNPFQ---FRHLTLCHGYSDLARVPSPKVVLASQPDLECGFSRELFIQWC 346 Query: 539 PDPRNSIIFVSYQAEGTLGR 558 DP+NS+I GTL R Sbjct: 347 QDPKNSVILTYRTTPGTLAR 366 >gi|11423200 hypothetical protein FLJ20542 [Homo sapiens] Length = 341 Score = 81.1 bits (197), Expect = 3e-14 Identities = 57/200 (28%), Positives = 104/200 (51%), Gaps = 15/200 (7%) Query: 452 IDAPIYLD-GMIWEATAIHTAYPEYLSRRLREQIFKEGYNPFLSEIFHPVANSKERQDII 510 + PIY G+ +A + + + ++++R+ + + E H A + Sbjct: 2 LKVPIYFSTGLTEKANHYYKLFIPWTNQKIRKTFVQRN----MFEFKHIKAFDRA---FA 54 Query: 511 DSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSIIFVSYQAEGTLGRQVQSGVREIPMV 570 D+ P ++ A+ GML G S++ F++ A + +N +I Y +GT+G ++ SG R++ M Sbjct: 55 DNPGPMVVFATPGMLHAGQSLQIFRKWAGNEKNMVIMPGYCVQGTVGHKILSGQRKLEM- 113 Query: 571 GEEGRTEVIKVNMEVHTIDGFSGHADRRELMNYVAKVRPRPERVITVHGEPQKCLDLATS 630 EGR +V++V M+V + FS HAD + +M V + PE V+ VHGE +K L Sbjct: 114 --EGR-QVLEVKMQVEYM-SFSAHADAKGIMQLVGQA--EPESVLLVHGEAKKMEFLKQK 167 Query: 631 IHRKFGLSTRAPNNLDTIRL 650 I ++ ++ P N +T+ L Sbjct: 168 IEQELRVNCYMPANGETVTL 187 >gb|AAD46873.1|AF160933_1 (AF160933) BcDNA.LD14168 [Drosophila melanogaster] >gi|7301732|gb|AAF56844.1| (AE003768) BcDNA:LD14168 gene product [Drosophila melanogaster] Length = 756 Score = 80.8 bits (196), Expect = 5e-14 Identities = 92/398 (23%), Positives = 165/398 (41%), Gaps = 39/398 (9%) Query: 189 IRITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKE-G 247 I++ + G + ++Q D+ +L+D G + FDA + + ++ Sbjct: 5 IKLHTISGAMDESPPCYILQIDDVRILLDCGWD-----------EKFDANFIKELKRQVH 53 Query: 248 LLDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPL 307 LDA++++H H G LPYL + PIY T P + + D + G L Sbjct: 54 TLDAVLLSHPDAYHLGALPYLVGKLGLNCPIYATIPVFKMGQMFMYDLYMSHFNMGDFDL 113 Query: 308 YRPRDIKEVIKHTITLDYGE---VRDISPDIRLTLHNAGHILGSAIVHLHIGNGLHNIAI 364 + D+ + L Y + ++D I +T NAGH++G I + + G +I Sbjct: 114 FSLDDVDTAFEKITQLKYNQTVSLKDKGYGISITPLNAGHMIGGTIWKI-VKVGEEDIVY 172 Query: 365 TGDFKFIPTRLLEPANAKFPRLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGG 424 DF R L + +L++ Y A Q R +++L+ I QT++ G Sbjct: 173 ATDFNHKKERHLSGCELDRLQRPSLLITDAY-NAQYQQARRRARDEKLMTNILQTVRNNG 231 Query: 425 KVLIPAMAVGRAQEVMMVLEDYARIGAIDAPIY----LDGMIWEATAIHTAYPEYLSRRL 480 VLI GR E+ +L+ + Y L+ + + + E++S +L Sbjct: 232 NVLIAVDTAGRVLELAHMLDQLWKNKESGLMAYSLALLNNVSYNVIEFAKSQIEWMSDKL 291 Query: 481 REQIFKEGYNPFL---SEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQL 537 + NPF ++ H +A+ + P +++AS+ L G + + F Q Sbjct: 292 TKAFEGARNNPFQFKHIQLCHSLADVYKL-----PAGPKVVLASTPDLESGFTRDLFVQW 346 Query: 538 APDPRNSIIFVSYQAEGTL----------GRQVQSGVR 565 A + NSII + + GTL G+Q++ VR Sbjct: 347 ASNANNSIILTTRTSPGTLAMELVENCAPGKQIELDVR 384 >gi|8923512 hypothetical protein FLJ20542 [Homo sapiens] >gi|7020719|dbj|BAA91246.1| (AK000549) unnamed protein product [Homo sapiens] Length = 292 Score = 80.8 bits (196), Expect = 5e-14 Identities = 48/140 (34%), Positives = 81/140 (57%), Gaps = 7/140 (5%) Query: 511 DSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSIIFVSYQAEGTLGRQVQSGVREIPMV 570 D+ P ++ A+ GML G S++ F++ A + +N +I Y +GT+G ++ SG R++ M Sbjct: 16 DNPGPMVVFATPGMLHAGQSLQIFRKWAGNEKNMVIMPGYCVQGTVGHKILSGQRKLEM- 74 Query: 571 GEEGRTEVIKVNMEVHTIDGFSGHADRRELMNYVAKVRPRPERVITVHGEPQKCLDLATS 630 EGR +V++V M+V + FS HAD + +M V + PE V+ VHGE +K L Sbjct: 75 --EGR-QVLEVKMQVEYM-SFSAHADAKGIMQLVGQA--EPESVLLVHGEAKKMEFLKQK 128 Query: 631 IHRKFGLSTRAPNNLDTIRL 650 I ++ ++ P N +T+ L Sbjct: 129 IEQELRVNCYMPANGETVTL 148 >pir||T32487 hypothetical protein F09G2.4 - Caenorhabditis elegans >gi|2435621|gb|AAB71322.1| (AF026215) F09G2.4 gene product [Caenorhabditis elegans] Length = 843 Score = 78.8 bits (191), Expect = 2e-13 Identities = 99/431 (22%), Positives = 169/431 (38%), Gaps = 52/431 (12%) Query: 189 IRITGLGGFREVGRSALLVQTDESYVLVDFGVNVAALNDPYKAFPHFDAPEFQYVLKEGL 248 I++ G ++ G L+Q D Y+L+D G D +F+ + ++ K Sbjct: 5 IKLKVFSGAKDEGPLCYLLQVDGDYILLDCGW------DERFGLQYFEELK-PFIPK--- 54 Query: 249 LDAIIITHAHLDHSGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKDFIEIQQSNGQDPLY 308 + A++I+H H G LPYL P+Y T P + + D + + Y Sbjct: 55 ISAVLISHPDPLHLGGLPYLVSKCGLTAPVYATVPVYKMGQMFIYDMVYSHLDVEEFEHY 114 Query: 309 RPRDIKEVIKHTITLDYGEVRDISPD--IRLTLHNAGHILGSAIVHLHIGNGLHNIAITG 366 D+ + + Y + + D + T AGH+LG +I + G +I Sbjct: 115 TLDDVDTAFEKVEQVKYNQTVVLKGDSGVHFTALPAGHMLGGSIWRICRVTG-EDIVYCV 173 Query: 367 DFKFIPTRLLEPANA-KFPRLETLVMESTYGGANDIQMP---REEAEKRLIEVIHQTLKR 422 DF R L + F R L+ GA+ I +P R++ +++L+ I +T+++ Sbjct: 174 DFNHKKERHLNGCSFDNFNRPHLLIT-----GAHHISLPQMRRKDRDEQLVTKILRTVRQ 228 Query: 423 GGKVLIPAMAVGRAQEVMMVLEDYARIGAIDAPIYLDGMIWEATAIHTAYPEYLSRRLRE 482 G +I GR E+ +L+ Y M+ + + + + E Sbjct: 229 KGDCMIVIDTAGRVLELAHLLDQLWSNADAGLSTYNLVMMSHVASSVVQFAKSQLEWMNE 288 Query: 483 QIFKEG-----YNPFLSEIFHPVANSKERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQL 537 ++FK YNPF + V Q+++ P +++ SS + G S E F Sbjct: 289 KLFKYDSSSARYNPFTLK---HVTLCHSHQELMRVRSPKVVLCSSQDMESGFSRELFLDW 345 Query: 538 APDPRNSIIFVSYQAEGTLGRQVQSGVREIPMVGEEGRTEVIKVNMEVHTIDGFSGHADR 597 DPRN +I + A TL ++ VNM DG H DR Sbjct: 346 CSDPRNGVILTARPASFTLAAKL--------------------VNMAERANDGVLKHEDR 385 Query: 598 RELMNYVAKVR 608 L++ V K R Sbjct: 386 --LISLVVKKR 394 >dbj|BAB01576.1| (AB045994) unnamed protein product [Macaca fascicularis] Length = 328 Score = 73.4 bits (177), Expect = 8e-12 Identities = 47/162 (29%), Positives = 87/162 (53%), Gaps = 10/162 (6%) Query: 385 RLETLVMESTYGGANDIQMPREEAEKRLIEVIHQTLKRGGKVLIPAMAVGRAQEVMMVLE 444 R L+ ESTY A I+ + E+ ++ +H+T++RGGKVLIP A+GRAQE+ ++LE Sbjct: 132 RPNLLITESTY--ATTIRDSKRCRERDFLKKVHETVERGGKVLIPVFALGRAQELCILLE 189 Query: 445 DYARIGAIDAPIYLD-GMIWEATAIHTAYPEYLSRRLREQIFKEGYNPFLSEIFHPVANS 503 + + PIY G+ +A + + + ++++R+ + + E H A Sbjct: 190 TFWERMNLKVPIYFSTGLTEKANHYYKLFIPWTNQKIRKTFVQRN----MFEFKHIKAFD 245 Query: 504 KERQDIIDSNEPAIIIASSGMLVGGPSVEYFKQLAPDPRNSI 545 + D+ P ++ A+ GML G S++ F++ A + +N + Sbjct: 246 RA---FADNPGPMVVFATPGMLHAGQSLQIFRKWAGNEKNMV 284 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.320 0.140 0.402 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 243916695 Number of Sequences: 2977 Number of extensions: 10812766 Number of successful extensions: 25887 Number of sequences better than 1.0e-10: 48 Number of HSP's better than 0.0 without gapping: 11 Number of HSP's successfully gapped in prelim test: 37 Number of HSP's that attempted gapping in prelim test: 25658 Number of HSP's gapped (non-prelim): 59 length of query: 651 length of database: 189,106,746 effective HSP length: 57 effective length of query: 594 effective length of database: 154,992,987 effective search space: 92065834278 effective search space used: 92065834278 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.8 bits) S2: 168 (69.9 bits)