BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1897 (dfp) DE:DNA/pantothenate metabolism flavoprotein (dfp) (401 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||E75114 dna/pantothenate metabolism flavoprotein (dfp) PAB18... 777 0.0 pir||G71018 pantothenate metabolism flavoprotein dfp homolog PH1... 719 0.0 gi|11499235 pantothenate metabolism flavoprotein (dfp) [Archaeog... 328 9e-89 pir||D69029 pantothenate metabolism flavoprotein dfp homolog MTH... 321 1e-86 sp|Q58323|DFP_METJA DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOM... 269 3e-71 gb|AAK40553.1| DNA/pantothenate metabolism flavoprotein (dfp) [S... 269 4e-71 gb|AAG19087.1| (AE005007) pantothenate metabolism flavoprotein; ... 266 4e-70 pir||B70371 pantothenate metabolism flavoprotein dfp - Aquifex a... 237 2e-61 sp|O51752|DFP_BORBU DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOM... 226 4e-58 pir||A72498 probable DNA/pantothenate metabolism flavoprotein AP... 224 1e-57 pir||A82351 DNA/pantothenate metabolism flavoprotein VC0215 [imp... 217 2e-55 pir||A72223 pantothenate metabolism flavoprotein dfp homolog TM1... 211 1e-53 pir||D81819 hypothetical protein NMA1916 [imported] - Neisseria ... 208 7e-53 pir||A81058 DNA/pantothenate metabolism flavoprotein NMB1658 [im... 208 9e-53 dbj|BAB06229.1| (AP001515) flavoprotein [Bacillus halodurans] 205 1e-51 gb|AAF04763.1| (AF104227) pantothenate metabolism flavoprotein h... 201 1e-50 pir||B82982 DNA/pantothenate metabolism flavoprotein PA5320 [imp... 198 7e-50 pir||D69878 pantothenate metabolism flavoprotein dfp homolog ylo... 196 3e-49 emb|CAC12018.1| (AL445065) DNA/pantothenate metabolism flavoprot... 193 3e-48 sp|P44953|DFP_HAEIN DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOM... 190 2e-47 gb|AAD21550.1| (AF088896) pantothenate metabolism flavoprotein [... 184 2e-45 emb|CAB93357.1| (AL357523) putative flavoprotein homologue (part... 184 2e-45 sp|P71661|DFP_MYCTU DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOM... 173 4e-42 sp|P24285|DFP_ECOLI DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN >gi... 173 4e-42 gb|AAA61992.1| (L10328) dfp (CG Site No. 18430) [Escherichia coli] 172 5e-42 pir||H82842 DNA/pantothenate metabolism flavoprotein XF0149 [imp... 171 9e-42 pir||H75501 DNA/pantothenate metabolism flavoprotein - Deinococc... 167 2e-40 sp|P73881|DFP_SYNY3 DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOM... 166 5e-40 gb|AAB97414.1| (AF042096) panthotenate metabolism flavoprotein [... 143 4e-33 pir||E71889 pantothenate metabolism flavoprotein dfp homolog HP0... 134 2e-30 pir||A64625 pantothenate metabolism flavoprotein dfp homolog HP0... 133 3e-30 pir||F81354 DNA /pantothenate metabolism flavoprotein Cj0822 [im... 125 1e-27 sp|Q54433|DFP_STRMU DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOM... 94 3e-18 gi|9634784 ORF FPV114 HAL3 domain [Fowlpox virus] >gi|7271612|gb... 80 3e-14 pir||T37719 thymidylate synthase-like DNA metabolism protein - f... 71 3e-11 >pir||E75114 dna/pantothenate metabolism flavoprotein (dfp) PAB1897 - Pyrococcus abyssi (strain Orsay) >gi|5458141|emb|CAB49630.1| (AJ248285) DNA/pantothenate metabolism flavoprotein (dfp) [Pyrococcus abyssi] Length = 401 Score = 777 bits (1985), Expect = 0.0 Identities = 401/401 (100%), Positives = 401/401 (100%) Query: 1 MLSHIKLIYATKSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKII 60 MLSHIKLIYATKSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKII Sbjct: 1 MLSHIKLIYATKSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKII 60 Query: 61 HPYAMEFATGNPVITEITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVT 120 HPYAMEFATGNPVITEITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVT Sbjct: 61 HPYAMEFATGNPVITEITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVT 120 Query: 121 TVVTTAFPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVATIDEI 180 TVVTTAFPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVATIDEI Sbjct: 121 TVVTTAFPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVATIDEI 180 Query: 181 VYRVIKKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTL 240 VYRVIKKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTL Sbjct: 181 VYRVIKKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTL 240 Query: 241 IRTRGSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKS 300 IRTRGSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKS Sbjct: 241 IRTRGSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKS 300 Query: 301 DKSITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGNTL 360 DKSITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGNTL Sbjct: 301 DKSITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGNTL 360 Query: 361 EAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEIEKKI 401 EAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEIEKKI Sbjct: 361 EAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEIEKKI 401 >pir||G71018 pantothenate metabolism flavoprotein dfp homolog PH1444 - Pyrococcus horikoshii >gi|3257868|dbj|BAA30551.1| (AP000006) 401aa long hypothetical protein DFP [Pyrococcus horikoshii] Length = 401 Score = 719 bits (1835), Expect = 0.0 Identities = 361/401 (90%), Positives = 389/401 (96%) Query: 1 MLSHIKLIYATKSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKII 60 ML+H+K IYA KSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVM+PSATKII Sbjct: 1 MLNHVKRIYAKKSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMTPSATKII 60 Query: 61 HPYAMEFATGNPVITEITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVT 120 HPYAMEFATGNPVITEITG IEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVT Sbjct: 61 HPYAMEFATGNPVITEITGFIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVT 120 Query: 121 TVVTTAFPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVATIDEI 180 TVVTTAFPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVA+IDEI Sbjct: 121 TVVTTAFPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVASIDEI 180 Query: 181 VYRVIKKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTL 240 VYRVI+KLHPKTL+GKRVL+TAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTL Sbjct: 181 VYRVIRKLHPKTLKGKRVLVTAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTL 240 Query: 241 IRTRGSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKS 300 I+T+GSV SFVENQI+VETVEEML AIE+ELT+KKYDVVIMAAAVSDFKPKIKA++KIKS Sbjct: 241 IKTKGSVNSFVENQIQVETVEEMLAAIEKELTEKKYDVVIMAAAVSDFKPKIKAEDKIKS 300 Query: 301 DKSITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGNTL 360 +KSIT+ELVPNPKII +IKE+Q DVFLVGFKAET+MEKLI EAKKQIE A SD+VIGNTL Sbjct: 301 NKSITIELVPNPKIIDRIKELQPDVFLVGFKAETTMEKLIQEAKKQIERAKSDIVIGNTL 360 Query: 361 EAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEIEKKI 401 EAFGS+ESKV+I+G++F KELP+M KRELAERIWDEIEK++ Sbjct: 361 EAFGSDESKVIIIGRNFEKELPKMNKRELAERIWDEIEKRL 401 >gi|11499235 pantothenate metabolism flavoprotein (dfp) [Archaeoglobus fulgidus] >gi|7449270|pir||D69455 pantothenate metabolism flavoprotein dfp homolog AF1645 - Archaeoglobus fulgidus >gi|2648905|gb|AAB89597.1| (AE000989) pantothenate metabolism flavoprotein (dfp) [Archaeoglobus fulgidus] Length = 404 Score = 328 bits (831), Expect = 9e-89 Identities = 197/403 (48%), Positives = 280/403 (68%), Gaps = 18/403 (4%) Query: 1 MLS-HIKLIYATKSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKI 59 MLS H++ I +SRKL KKIVL + GSIAAVE VKLAREL+R GA+V AVMS +A KI Sbjct: 1 MLSVHLERIRGRRSRKLERKKIVLGVTGSIAAVETVKLARELVRRGADVTAVMSRAARKI 60 Query: 60 IHPYAMEFATGNPVITEITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPV 119 IHPYA+EFATG V+TEITGSIEHV L GE+ + ADL L+ P TANTISKIA GIDDTPV Sbjct: 61 IHPYALEFATGKRVVTEITGSIEHVNLLGEYGD-ADLFLIAPCTANTISKIAQGIDDTPV 119 Query: 120 TTVVTTAFPH-IPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVATID 178 TT TTA PI+I PAMHE+M ++ V ENI++L +G+EF+ PRIEEGKAK + + Sbjct: 120 TTFATTALGSGKPIIIVPAMHEAMMRNKAVLENIQRLIDMGIEFVQPRIEEGKAKFPSTE 179 Query: 179 EIVYRVIKKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEV 238 I V ++L+PK ++GKRV++T+G T E IDPIRFI+N SSG+MG+ +A E RGA+V Sbjct: 180 TICLHVERELYPKEMKGKRVVVTSGPTYEQIDPIRFISNKSSGRMGLEIALEFWRRGADV 239 Query: 239 TLIRTRGSVKSFVE-NQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEK 297 + ++ S S +I V +VE+M+ A+ E+ K D+ + +AA +DF +AK K Sbjct: 240 VHVTSKPSGMSLPNYKEIRVWSVEDMMKAVLYEI-GKGCDLFVSSAAAADFIVDAEAK-K 297 Query: 298 IKSDKSITLELVPNPKIIRKIKEIQSDVFLVGFKAETSM--EKLISEAKKQIESAGSDLV 355 IK+ + L+L +PKII+++++I S ++GFKAET M ++L+ A +++ ++V Sbjct: 298 IKTAPELVLKLKESPKIIKEVRKIYSG-HIIGFKAETGMSDDELLKVASEKMADDNLNMV 356 Query: 356 IGNTL--EAFGSEESKVVIV---GKDFVKELPRMKKRELAERI 393 + N + G+E+++V+I+ +++V+ L K+ +AERI Sbjct: 357 VANDVLERGMGTEDTRVLILTPKRQEWVEGL----KQHVAERI 395 >pir||D69029 pantothenate metabolism flavoprotein dfp homolog MTH1216 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622326|gb|AAB85705.1| (AE000889) pantothenate metabolism flavoprotein [Methanobacterium thermoautotrophicum] Length = 386 Score = 321 bits (813), Expect = 1e-86 Identities = 187/390 (47%), Positives = 257/390 (64%), Gaps = 21/390 (5%) Query: 20 KIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITEITG 79 +I+L + GS+AA+E VKLAREL R GAEV MS A +IIHPYAMEFATG+ + E+TG Sbjct: 2 EIILCVTGSVAAIEAVKLARELGRQGAEVKCFMSEDACRIIHPYAMEFATGSKPVLELTG 61 Query: 80 SIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPH-IPIMIAPAM 138 IEHV+ AG ADLILV PATAN I K+A + D P+++++ TA PI++ P+M Sbjct: 62 EIEHVKYAG-----ADLILVAPATANIIGKLAYRLADNPISSLLLTASGMGTPIVMVPSM 116 Query: 139 HESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVATIDEIVYRVIKKLHPKTLEGKRV 198 HE+MY ENI +LK+ GV FI PR++EGKAK ID IV +++ + L+GKRV Sbjct: 117 HEAMYA--AAAENIMRLKEEGVIFIEPRMDEGKAKFPDIDTIVLEAMRQTSSQRLQGKRV 174 Query: 199 LITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIRTRGSVKSFVENQI--- 255 L++ G T E IDP+R ITN SSGKMG+A+A A GA+VT++ G+V + Q+ Sbjct: 175 LVSLGGTYEPIDPVRGITNRSSGKMGLAIARRAYIEGADVTVV--AGTVSVEIPPQLRSF 232 Query: 256 EVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSDKSITLELVPNPKII 315 ET EEM + E + +DV I AAAV+DFKP + + KI S + ++EL PNPK+I Sbjct: 233 RAETAEEMAERVRELVA--DHDVFISAAAVADFKP-VYTERKISSSEEFSVELRPNPKVI 289 Query: 316 RKIKEIQSDVFLVGFKAETSM--EKLISEAKKQIESAGSDLVIGN--TLEAFGSEESKVV 371 +EI + F+VGFKAE + E L+ A+KQI +G D+V+ N ++E FGS+ ++ + Sbjct: 290 GIAREINPEAFIVGFKAEYDVDNEALVESARKQIRESGVDMVVANDVSVEGFGSDRNRAI 349 Query: 372 IVGKDFVKELPRMKKRELAERIWDEIEKKI 401 IV D V ELP M+K ELA I DE+ +K+ Sbjct: 350 IV-SDMVTELPLMEKEELASIIIDEVIRKV 378 >sp|Q58323|DFP_METJA DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOMOLOG >gi|2129175|pir||A64414 pantothenate metabolism flavoprotein MJ0913 - Methanococcus jannaschii >gi|1591587|gb|AAB98918.1| (U67535) pantothenate metabolism flavoprotein (dfp) [Methanococcus jannaschii] Length = 403 Score = 269 bits (681), Expect = 3e-71 Identities = 169/403 (41%), Positives = 250/403 (61%), Gaps = 18/403 (4%) Query: 6 KLIYATKSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAM 65 KL+ TKS+ L KKI++A+ SIAA+E KL RELIRHGAEV+ +++ KII A+ Sbjct: 10 KLLKGTKSKLLENKKILVAVTSSIAAIETPKLMRELIRHGAEVYCIITEETKKIIGKEAL 69 Query: 66 EFATGNPVITEITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTT 125 +F GN V EITG IEH+ L N+ D +L+ PATAN ISKI GI D V T Sbjct: 70 KFGCGNEVYEEITGDIEHILL----YNECDCLLIYPATANIISKINLGIADNIVNTTALM 125 Query: 126 AFPHIPIMIAPAMHESMYKHPIVRENIEKLK-KLGVEFIGPRIEEGKAKVATIDEIVYRV 184 F + PI I PAMHE+M+ ++ +I+KLK K + I P+ EEGKAKVA I+++V V Sbjct: 126 FFGNKPIFIVPAMHENMFN--AIKRHIDKLKEKDKIYIISPKFEEGKAKVANIEDVVKAV 183 Query: 185 IKKL-HPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIRT 243 I+K+ + EG RVLI G T E+ID +R I+N SSGKMGVALAE G V +I Sbjct: 184 IEKIGNNLKKEGNRVLILNGGTVEFIDKVRVISNLSSGKMGVALAEAFCKEGFYVEVITA 243 Query: 244 RGSVKSFVENQIEVETVEEMLG-AIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSDK 302 G + +V T +EML AIE K +D++I +AA+SDF + + K+ S++ Sbjct: 244 MGLEPPYYIKNHKVLTAKEMLNKAIE---LAKDFDIIISSAAISDFTVE-SFEGKLSSEE 299 Query: 303 SITLELVPNPKIIRKIKEIQSDVFLVGFKAETSME--KLISEAKKQIESAGSDLVIGNTL 360 + L+L NPK++ +++ I D ++GFKAE +++ +LI+ AK+++ +++I N L Sbjct: 300 ELILKLKRNPKVLEELRRIYKDKVIIGFKAEYNLDEKELINRAKERLNKYNLNMIIANDL 359 Query: 361 EA--FGSEESKVVIVGKDFVKELPRMKKRELAERIWDEIEKKI 401 FG + +V I+ K V+++ KK E++ERI ++++K + Sbjct: 360 SKHYFGDDYIEVYIITKYEVEKISGSKK-EISERIVEKVKKLV 401 >gb|AAK40553.1| DNA/pantothenate metabolism flavoprotein (dfp) [Sulfolobus solfataricus] Length = 413 Score = 269 bits (680), Expect = 4e-71 Identities = 163/408 (39%), Positives = 254/408 (61%), Gaps = 18/408 (4%) Query: 6 KLIYATKSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAM 65 K I + S +L KKI+LA+ GS+A + + LAR L+R+GAEV ++S A K+I P Sbjct: 10 KKIIGSISNELADKKILLAVTGSVAIYKSLDLARSLMRNGAEVSVIISKDAAKLISPEMF 69 Query: 66 EFATGNPVITEITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVT-TVVT 124 ++ATGN V+T++TG +EHV LA ++ D+++V P+TANT+ KIA GI DTP+T T + Sbjct: 70 KWATGNNVVTKLTGDLEHVSLAEDN----DVMIVAPSTANTMVKIAYGIADTPITATALN 125 Query: 125 TAFPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVATIDEIVYRV 184 P++I P+MH MY P V + ++LK++GVE I P I A ++ + R+ Sbjct: 126 FVGMKKPLIIVPSMHLQMYISPQVADAADRLKRIGVEVIEPEIVGDLAHYPKLEYLTSRI 185 Query: 185 IK-KLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLI-- 241 L K L G +L TAG TREY+D +RFI+N SSG MG+++A EA FRGA+V +I Sbjct: 186 TSYVLRGKDLSGFNILATAGPTREYLDSVRFISNPSSGTMGISIANEAYFRGAKVRVICG 245 Query: 242 RTRGSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSD 301 ++ +V++ + VET EEML + + + K++VVI+A A +D+K K K+ KI S Sbjct: 246 PISSKIEPYVKDIVYVETTEEMLNEVVKSIENGKFNVVILAGAPADYKFKNKSDTKIDSH 305 Query: 302 KSI-TLELVPNPKIIRKIKEIQSDVFLVGFKAET--SMEKLISEAKKQIESAGSDLVIGN 358 I +EL PKI I++ +V LVGF AET S E+LI +AK ++ G DL++ N Sbjct: 306 TEIPKVELERTPKISEYIRKY--NVLLVGFSAETVNSDEELIEKAKIKMRRHGFDLIVAN 363 Query: 359 TLE----AFGSEESKVVIVGKD-FVKELPRMKKRELAERIWDEIEKKI 401 + F SE ++V+++ K+ V+++P+ K +A +I D +++++ Sbjct: 364 NVRRKDIGFSSEYNEVIVIDKNGDVRKIPKNFKTVIARKILDIVKEQL 411 >gb|AAG19087.1| (AE005007) pantothenate metabolism flavoprotein; Dfp [Halobacterium sp. NRC-1] Length = 392 Score = 266 bits (672), Expect = 4e-70 Identities = 156/392 (39%), Positives = 233/392 (58%), Gaps = 19/392 (4%) Query: 16 LVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVIT 75 L G + + + GSIAAV+ V+ EL R GA V AVM+ SA IIHP+A+EFAT NPV+T Sbjct: 2 LSGVNVAVGVTGSIAAVKVVEFVHELRRRGACVRAVMTESAQGIIHPWAVEFATENPVVT 61 Query: 76 EITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAF-PHIPIMI 134 EITG++ HVEL G + AD+ +V PATANT+ KIA +DD+PVTT VTTA +P+++ Sbjct: 62 EITGTVPHVELCGR-DGWADVFVVAPATANTVGKIAAAVDDSPVTTCVTTAVGADVPVVV 120 Query: 135 APAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVATIDEIVYRVIKKLHPKTLE 194 PAMHE MY HP VR+ I+++ GV + PRIEEGKAK+ IV+ + + L Sbjct: 121 VPAMHEPMYDHPGVRDAIDRVSSWGVSVVDPRIEEGKAKLPRESTIVHETARAAGEQPLA 180 Query: 195 GKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIR--TRGSVKSFVE 252 G V++T+GAT E IDP+R +TN +SG+ G A+A RGA VTL+ + G + + Sbjct: 181 GTHVVVTSGATSEAIDPVRVLTNRASGRTGRAVAAACYVRGARVTLVHDASDGGAVPYAD 240 Query: 253 NQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSDK-SITLELVPN 311 + +V + EM A D ++ AAA+SD+ + A EK++S + + L L P Sbjct: 241 VR-DVSSAAEMTAATLTACADA--DALVSAAAISDYTVE-AADEKLRSGREDVALSLEPT 296 Query: 312 PKIIRKIKEIQSDVFLVGFKAETSM-------EKLISEAKKQIESAGSDLVIGNTLEAFG 364 K++ +++ D+ +VGFKAET + +++ A+ ++ G V+ N G Sbjct: 297 RKLVGAVRDDNPDLPIVGFKAETPADDGTAGDDSMVAAARSLLQRDGLAFVVANDAGVMG 356 Query: 365 SEESKVVIVGKDFVKELPRMKK---RELAERI 393 ++E++ + V D V E K+ +AER+ Sbjct: 357 NDETRALFVTADSVSEYAGHKRGLGARIAERL 388 >pir||B70371 pantothenate metabolism flavoprotein dfp - Aquifex aeolicus >gi|2983357|gb|AAC06944.1| (AE000708) pantothenate metabolism flavoprotein [Aquifex aeolicus] Length = 388 Score = 237 bits (598), Expect = 2e-61 Identities = 148/383 (38%), Positives = 221/383 (57%), Gaps = 20/383 (5%) Query: 21 IVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITEITGS 80 I++ + G IA+ + +L REL R G V +++P A K + P + +GN T+ Sbjct: 3 ILIGVCGGIASYKVCELVRELKRKGHSVKTILTPFAEKFMSPLTFQTLSGNKAYTDKDWE 62 Query: 81 IE---HVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIPIMIAPA 137 E H+ LA AD+ L+ PATANTI+KIA GI D +TT + P+++APA Sbjct: 63 EEPLAHINLA----RWADVFLIAPATANTIAKIANGISDNLLTTTILAYGK--PLLVAPA 116 Query: 138 MHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEIVYRVIKKLHPK 191 M+ MYK P +EN++KLK+ G I P E G+ K+A+ID ++ + K Sbjct: 117 MNTVMYKSPSTQENLKKLKEWGHVIIEPEFGVLACKEVGEGKLASIDRLIDWIYYVSEEK 176 Query: 192 TLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIRTRGSVKSFV 251 L+GK+VLIT GAT+E+IDP+RFI+N SSG+MG +LA ++GAEV +I + K Sbjct: 177 PLKGKKVLITCGATKEFIDPVRFISNYSSGEMGFSLARIFRWKGAEVKVIAGTTTAKEPP 236 Query: 252 ENQ-IEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSDKSITLELVP 310 E + I V+T EEM + E D+V+M AAV+DFKP +KEKIK I LELV Sbjct: 237 EVEIIRVQTTEEMREKVLEHYDWA--DIVVMNAAVADFKPSKVSKEKIKKRDKILLELVK 294 Query: 311 NPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGNTLEAFGSEESKV 370 NP I+ ++ + LVGF E+ + L+ A++++E DL++ N ++ G +E + Sbjct: 295 NPDILEELGRKKGYKILVGFALES--DNLLEYAREKLERKNLDLIVANPVKVMGKKEHEG 352 Query: 371 VIVGKDFVKELPRMKKRELAERI 393 ++ KD + ELP+ K E A I Sbjct: 353 YLITKDQIVELPKGSKLENARFI 375 >sp|O51752|DFP_BORBU DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOMOLOG >gi|7449264|pir||C70201 pantothenate metabolism flavoprotein dfp homolog BB0812 - Lyme disease spirochete >gi|2688739|gb|AAC67145.1| (AE001179) pantothenate metabolism flavoprotein (dfp) [Borrelia burgdorferi] Length = 390 Score = 226 bits (570), Expect = 4e-58 Identities = 150/391 (38%), Positives = 232/391 (58%), Gaps = 26/391 (6%) Query: 19 KKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITEIT 78 K I++ I G IA+ + V + L++ G +V +M+ +ATK I P +E + N +IT + Sbjct: 5 KHILIGICGGIASYKSVYIVSSLVKLGYKVKVIMTQNATKFITPLTLETISKNKIITNLW 64 Query: 79 ----GSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIPIMI 134 +EH+++A A LILV PAT NTISKIA GI D +TT+++ + P Sbjct: 65 DLDHNEVEHIKIA----KWAHLILVIPATYNTISKIASGIADDALTTIISASTA--PTYF 118 Query: 135 APAMHESMYKHPIVRENIEKLKKLGVEFIGPR------IEEGKAKVATIDEIVYRVIKKL 188 A AM+ MY +PI++ENI+KLK +FI P ++ D+I+ ++ + Sbjct: 119 AIAMNNIMYSNPILKENIKKLKTYNYKFIEPDKGFLACSSNALGRLKNEDKIIKIILNEF 178 Query: 189 HPKT-LEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIRTRGSV 247 + K L+ K++LITA T E IDPIR+ +N S+GKMG LA+EA GA+VT+I T + Sbjct: 179 NQKDYLKNKKILITASRTEELIDPIRYFSNTSTGKMGFCLAQEAVKLGAQVTII-TGPTN 237 Query: 248 KSFVE--NQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSDK--S 303 ++ E N I+++T EM E K++++I AAAV+DFKPK KIK +K Sbjct: 238 ENDPEGVNIIKIKTAMEMYK--EALKIYNKFEIIIGAAAVADFKPKHIFNSKIKKNKINR 295 Query: 304 ITLELVPNPKIIRKIKEIQ-SDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGNTLEA 362 + ++LV NP II+ I + + ++GF AE S + LI +AK++++ D +I N L+ Sbjct: 296 LYIKLVKNPDIIQHIGHNKLKNQIVIGFCAENS-KNLIQKAKEKLKKKNLDFIIANELKY 354 Query: 363 FGSEESKVVIVGKDFVKELPRMKKRELAERI 393 FGS+ +KV I+ K +KELP M+K E+A+ I Sbjct: 355 FGSKLNKVYIINKQSIKELPEMEKSEVAKEI 385 >pir||A72498 probable DNA/pantothenate metabolism flavoprotein APE1959 - Aeropyrum pernix (strain K1) >gi|5105657|dbj|BAA80969.1| (AP000063) 437aa long hypothetical DNA/pantothenate metabolism flavoprotein [Aeropyrum pernix] Length = 437 Score = 224 bits (565), Expect = 1e-57 Identities = 145/393 (36%), Positives = 219/393 (54%), Gaps = 17/393 (4%) Query: 18 GKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITEI 77 GK IVL + S+A + LAR L+R GA V VM+P A K++ P +A+G PV T Sbjct: 47 GKTIVLGVTASVALYRSLDLARWLLRRGARVITVMTPEAAKLVSPEMFHWASGGPVYTGF 106 Query: 78 TGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPH-IPIMIAP 136 TG +EH+ +A A ++V PAT +T++KIA G+ D PV + + P++ P Sbjct: 107 TGGVEHISIA----RAASAMVVAPATLSTLAKIAHGVVDNPVALAAVSIMGYGKPVIAVP 162 Query: 137 AMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVATIDEI--VYRVIKKLHPKTLE 194 AMH +MY+ P RE +++L+ GV + P+IE G AK + + + + LE Sbjct: 163 AMHGNMYESPQAREVVDRLRSQGVLVVDPKIEGGVAKYPDTHAVGRITAAQARKGLRDLE 222 Query: 195 GKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIRTRGSVK-SFVEN 253 G R L+T G+TRE+ID +RFI+N SSG MG+ A E RGAEV ++ SV+ + N Sbjct: 223 GIRALVTLGSTREWIDRVRFISNPSSGVMGLEAALELYARGAEVDVVAGYTSVEIPHLFN 282 Query: 254 QIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSDKSITLELVPNPK 313 ++ ET E+M A+EE +K++YD V+ AAA DF+P + KI+S + + LEL P PK Sbjct: 283 TVKTETTEDMAAAVEELTSKREYDAVVAAAAPVDFRPAGAFEGKIRSGQRLVLELEPTPK 342 Query: 314 IIRKIKEIQSDVFLVGFKAE--TSMEKLISEAKKQIESAGSDLVIGNTL----EAFGSEE 367 ++ I + LV F AE +++ L A +++E +DLV+ N + F S Sbjct: 343 VLEGI--ARRPKVLVAFAAEYVDNLDSLRDPALEKMEKYDADLVVANRVGVEGVGFASPL 400 Query: 368 SKVVIVGKDFVKELPRMKKREL-AERIWDEIEK 399 V+++ K L +E+ A I DEI K Sbjct: 401 LDVLMLDKSGEAVLKGSFHKEIVAAVIADEIAK 433 >pir||A82351 DNA/pantothenate metabolism flavoprotein VC0215 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9654622|gb|AAF93391.1| (AE004111) DNA/pantothenate metabolism flavoprotein [Vibrio cholerae] Length = 399 Score = 217 bits (546), Expect = 2e-55 Identities = 143/408 (35%), Positives = 230/408 (56%), Gaps = 30/408 (7%) Query: 14 RKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPV 73 + L GKKI+L I G IAA +C +L R L+ GA V VM+ +A + I P M+ +G PV Sbjct: 2 QSLAGKKILLGISGGIAAYKCAELTRRLVERGATVQVVMTHAAKEFITPLTMQAVSGRPV 61 Query: 74 ITEIT-----GSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFP 128 + S+ H+ELA ADL+L+ PATA+ I+++A G+ + +TT++ Sbjct: 62 SDSLLDPAAEASMGHIELA----KWADLVLLAPATADLIARMAAGMGNDLLTTLILAT-- 115 Query: 129 HIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEE------GKAKVATIDEIVY 182 P+ IAPAM++ MY++ +EN++ L + G GP E G ++ E+V Sbjct: 116 SAPVAIAPAMNQQMYRNIATQENLQTLIRRGYLTWGPAAGEQACGDVGPGRMLEPMELVA 175 Query: 183 RVIKKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIR 242 PK L GKRVLITAG TRE +DP+R+ITN SSGKMG ALA+ A GA+VTL+ Sbjct: 176 HCENFFAPKILVGKRVLITAGPTREALDPVRYITNHSSGKMGFALAKAAAQLGADVTLVS 235 Query: 243 TRGSVKSFV-ENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSD 301 + + V N+I+V++ EM A+ +E T + + I AAV+D++P+ A++KIK Sbjct: 236 GPVHLPTPVGVNRIDVQSGLEMHSAVMKEAT--SHQIFIACAAVADYRPQTVAEQKIKKS 293 Query: 302 K---SITLELVPNPKIIRKIKEI-QSDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIG 357 + ++T+E+V NP I+ + + ++ F VGF AET + + + A+ ++ D++ Sbjct: 294 RDNDTLTIEMVKNPDIVASVAALTENRPFTVGFAAET--QDVETYARSKLVRKNLDMICA 351 Query: 358 NTL----EAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEIEKKI 401 N + + F S ++ + + K+ LP K LA + I +++ Sbjct: 352 NDVSIAGQGFNSNDNALTLFWKEGQHSLPLTSKDALASAVMHLIHEQM 399 >pir||A72223 pantothenate metabolism flavoprotein dfp homolog TM1687 - Thermotoga maritima (strain MSB8) >gi|4982263|gb|AAD36754.1|AE001809_6 (AE001809) DNA/pantothenate metabolism flavoprotein [Thermotoga maritima] Length = 394 Score = 211 bits (532), Expect = 1e-53 Identities = 153/396 (38%), Positives = 222/396 (55%), Gaps = 30/396 (7%) Query: 20 KIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITEI-- 77 +IVL + IA + V LA +L + G E+H VM+P AT++I P A GN + Sbjct: 2 RIVLGVSSGIAIYKAVDLASKLRKEGHELHVVMTPDATRMISPVVFS-AVGNCSVYHDWM 60 Query: 78 ---TGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIPIMI 134 G I H E++ AD+++V PATANTISKIA GI D + T+V AF ++ Sbjct: 61 DVRNGWIPHTEIS----RTADVLVVAPATANTISKIANGIADN-LLTLVALAFDKDAKIL 115 Query: 135 APAMHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEIVYRVIKKL 188 P M+ MY + + +EN+EKLK G + P E GK + ++IV V Sbjct: 116 VPTMNYRMYSNKLFQENLEKLKNNGWFVVEPEEGHLACGEVGKGRYPENEKIVEAVHLLT 175 Query: 189 HPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIRTRGSVK 248 PK L GK+VLITAG TRE ID +RFITNASSGKMG ALA A+ GA V+L+ S+K Sbjct: 176 FPKKLAGKKVLITAGPTRERIDAVRFITNASSGKMGYALATVAKRMGARVSLVSGPTSLK 235 Query: 249 S--FVENQIEVETVEEMLGAIEEELTKK--KYDVVIMAAAVSDFKPKIKAKEKI-KSDKS 303 +V+ ++VE+ EEM EE+ K+ D+VIM AAV D++PK + K+ K++ Sbjct: 236 PPYYVDEFVKVESAEEMY----EEVMKRFEDTDIVIMNAAVGDYRPKKVFEGKLKKTEND 291 Query: 304 ITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSD-LVIGNTLEA 362 + L L I++++ + +S+ LVGF AE +E A K++ D LV+ + +A Sbjct: 292 LVLHLERTKDILKELGQRKSNQILVGFAAE--VENFEENAVKKLREKNLDLLVLNDARKA 349 Query: 363 FGSEESKVVIVGKD-FVKELPRMKKRELAERIWDEI 397 F S+ +V I G+D F+K + K +A I D + Sbjct: 350 FSSDRVEVYIYGRDGFIKRIDEDDKIRVACGILDVV 385 >pir||D81819 hypothetical protein NMA1916 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7380550|emb|CAB85137.1| (AL162757) hypothetical protein [Neisseria meningitidis Z2491] Length = 394 Score = 208 bits (525), Expect = 7e-53 Identities = 140/398 (35%), Positives = 218/398 (54%), Gaps = 27/398 (6%) Query: 17 VGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITE 76 +GK I+L + GSIAA + +L R L + G V VMS SAT+ + P + +GNPV+T+ Sbjct: 1 MGKHILLGVTGSIAAYKSCELVRLLKKQGHSVTVVMSRSATEFVSPLTFQALSGNPVLTD 60 Query: 77 ITGS-----IEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIP 131 GS +EH+ L AD+ L+ PA+ NT++KI G+ D +T + A P Sbjct: 61 THGSNGSNGMEHINLT----RNADVFLIAPASMNTVAKICNGVADNLLTNLA--AARKCP 114 Query: 132 IMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEIVYRVI 185 + IAPAM+ M+ +P + NI +L G+ P + E G ++ E++ + Sbjct: 115 LAIAPAMNVEMWLNPANQRNIAQLVSDGITVYMPGLGEQACGENGMGRMPEPAELLDLLP 174 Query: 186 KKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLI--RT 243 PK L GK++LITAGAT E IDP+R ITN SSGKMGVALA GAEV+LI + Sbjct: 175 DLWTPKILRGKKILITAGATFEAIDPVRGITNTSSGKMGVALARACRAAGAEVSLIHGQL 234 Query: 244 RGSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSDKS 303 + + + + ++ + E+M A+ + +K D I AAVSD+K K ++ +K K DK+ Sbjct: 235 QTELPFGISDTVQAVSAEDMHRAVHRLI--EKQDAFISVAAVSDYKVKNRSTQKFKKDKN 292 Query: 304 ---ITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAK-KQIESAGSDLVIGNT 359 +++EL NP I+ I + + F +GF AET E +++ A+ K+I+ +V + Sbjct: 293 AKPLSIELDENPDILASIASLPNPPFCIGFAAET--ENVMAYAREKRIKKKIPVIVANDV 350 Query: 360 LEAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEI 397 A G +++ I+G D P K E A +I + + Sbjct: 351 SIAMGKPTNRITIIGDDGELSFPETSKDEAAMQIVERL 388 >pir||A81058 DNA/pantothenate metabolism flavoprotein NMB1658 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7226910|gb|AAF42007.1| (AE002516) DNA/pantothenate metabolism flavoprotein [Neisseria meningitidis MC58] Length = 394 Score = 208 bits (524), Expect = 9e-53 Identities = 138/398 (34%), Positives = 219/398 (54%), Gaps = 27/398 (6%) Query: 17 VGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITE 76 +GK I+L + GSIAA + +L R L + G V VMS SAT+ + P + +GNPV+T+ Sbjct: 1 MGKHILLGVTGSIAAYKSCELVRLLKKQGHSVTVVMSRSATEFVSPLTFQALSGNPVLTD 60 Query: 77 ITGS-----IEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIP 131 G +EH+ L AD+ L+ PA+ NT++KI G+ D +T++ A P Sbjct: 61 THGGNGSNGMEHINLT----RNADVFLIAPASMNTVAKICNGVADNLLTSLA--AARKCP 114 Query: 132 IMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEIVYRVI 185 + IAPAM+ M+ +P + NI +L G+ P + E G ++ E++ + Sbjct: 115 LAIAPAMNVEMWLNPANQRNIAQLVSDGITVYMPGLGEQACGENGMGRMPEPAELLDLLP 174 Query: 186 KKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLI--RT 243 PK L+GK+VLITAGAT E IDP+R ITN SSGKMGVALA GAEV+LI + Sbjct: 175 DLWTPKILKGKKVLITAGATFEAIDPVRGITNISSGKMGVALARACRAAGAEVSLIHGQL 234 Query: 244 RGSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSDKS 303 + ++ + + ++ + E M A+ + K+ D I AAVSD++ K ++ +K K DK+ Sbjct: 235 QTALPFGISDTVQAVSAENMHRAVHRLIDKQ--DAFISVAAVSDYRVKNRSTQKFKKDKN 292 Query: 304 ---ITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGNTL 360 +++EL NP I+ I + + F +GF AET E +++ A+++ +++ N + Sbjct: 293 AKPLSIELDENPDILASIASLPNPPFCIGFAAET--ENVMTYAREKRIKKKLPMIVANDV 350 Query: 361 E-AFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEI 397 A G +++ I+G D P K E A RI + + Sbjct: 351 SIAMGKPTNRITIIGDDGELSFPETSKDEAAMRIVERL 388 >dbj|BAB06229.1| (AP001515) flavoprotein [Bacillus halodurans] Length = 404 Score = 205 bits (515), Expect = 1e-51 Identities = 136/398 (34%), Positives = 225/398 (56%), Gaps = 30/398 (7%) Query: 16 LVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVIT 75 L GK++VL + G IAA + A +L++ GAEV VM+ A K + P + T +PV Sbjct: 2 LQGKRVVLGVSGGIAAFKSAAFASKLVQAGAEVKVVMTEGAKKFVTPLTFQALTRHPVYD 61 Query: 76 EI-----TGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHI 130 + I H++LA + AD+I++ PATAN I K+A G+ D ++T++ Sbjct: 62 DTFSEPDPSEIAHIQLA----DWADVIIIAPATANLIGKLANGVADDMLSTMLLAT--KA 115 Query: 131 PIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEE------GKAKVATIDEIVYRV 184 PI +APAM+ +MY+HP V+ N+++L K G + P GK ++ ++++ + Sbjct: 116 PIYLAPAMNVNMYEHPAVQRNMQQLAKDGYRLLEPGAGYLACGWIGKGRMPEPEDLLKTI 175 Query: 185 IKKLHP--KTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIR 242 P +L GK+++ITAG T+E IDPIRF TN SSGKMG AL + A G VTLI Sbjct: 176 EVHFTPPSSSLAGKKIVITAGPTQETIDPIRFFTNRSSGKMGYALTKAARDFGGNVTLIS 235 Query: 243 TRGSV-KSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKI-KS 300 S+ K + + V++ ++M A+ E + DVVI AAV+D++P++ ++K+ K Sbjct: 236 GPTSLEKPDGVSVVNVKSAQDMYEAVLAEFSDA--DVVIKTAAVADYRPRVVHEQKVKKK 293 Query: 301 DKSITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGNTL 360 D +EL I++ + E + FLVGF AE+ +++ + A+K+++ +D+++ N + Sbjct: 294 DGDWVIELERTVDILKTLGEKKESQFLVGFAAES--QEVETYAQKKLKEKNADMIVANNV 351 Query: 361 ----EAFGSEESKVVIVGKD-FVKELPRMKKRELAERI 393 F ++ ++V + K VK LP M K E+A R+ Sbjct: 352 TEEGAGFQTDTNRVTVYFKQGDVKPLPLMTKDEVAHRL 389 >gb|AAF04763.1| (AF104227) pantothenate metabolism flavoprotein homolog [Listeria monocytogenes] Length = 399 Score = 201 bits (506), Expect = 1e-50 Identities = 146/403 (36%), Positives = 220/403 (54%), Gaps = 37/403 (9%) Query: 18 GKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITEI 77 GK I+LA+ G IA + V L +L + GA V +M+ A + + P + + + N V T+ Sbjct: 3 GKNILLAVSGGIAVYKAVALTSKLTQAGANVKVMMTAHAQEFVPPLSFQVLSKNDVYTDT 62 Query: 78 -----TGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIPI 132 + + H++LA + ADL++V PATAN I K+A GI D VTT + P+ Sbjct: 63 FDEKKSSVVAHIDLA----DWADLVIVAPATANVIGKMANGIADDMVTTTILAT--EAPV 116 Query: 133 MIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEG--------KAKVATIDEIVYRV 184 +APAM+ M +HP V NI +L GV FI P EEG + ++ ++IV R+ Sbjct: 117 WVAPAMNVHMIQHPAVIRNINRLYADGVRFIEP--EEGYLACGYVGRGRLEEPEKIVLRI 174 Query: 185 IKKLHP--KTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIR 242 + L+GK VL+TAGATRE +D IR+ TN S+GKMG ++AE A GA VTLI Sbjct: 175 AEFFQEDKNLLQGKNVLVTAGATREKLDLIRYFTNHSTGKMGFSIAESAARHGANVTLIT 234 Query: 243 TRGS--VKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKS 300 T + V VE I VE+ EEM A+ E K D+ +M AAV+D+ P + +KIK Sbjct: 235 TSKALPVPHGVE-AIYVESAEEMHQAVNER--KVSQDIFVMTAAVADYTPAQVSDQKIKK 291 Query: 301 DK-SITLELVPNPKIIRKIKEIQ-SDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGN 358 T+ + I+ +I + + S+ ++GF AET E + + A+K++ S +D+++ N Sbjct: 292 QPGDFTIAMKRTKDILLEIGQHKTSEQVVIGFAAET--ENVEANARKKLTSKNADMIVAN 349 Query: 359 TLE----AFGSEESKVVIVGKDFVKE-LPRMKKRELAERIWDE 396 + F + + V KD E LP + K+E+AE I E Sbjct: 350 NISEAGAGFSGDTNIVTFYRKDGSSEALPILDKKEVAEHIIKE 392 >pir||B82982 DNA/pantothenate metabolism flavoprotein PA5320 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9951637|gb|AAG08705.1|AE004944_9 (AE004944) DNA/pantothenate metabolism flavoprotein [Pseudomonas aeruginosa] Length = 402 Score = 198 bits (499), Expect = 7e-50 Identities = 129/385 (33%), Positives = 213/385 (54%), Gaps = 35/385 (9%) Query: 14 RKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPV 73 ++L K+IVL + G IAA + +L R L GAEV VM+ + I P ++ +G+PV Sbjct: 2 QRLYRKRIVLGVGGGIAAYKSAELVRRLRDQGAEVRVVMTQGGREFITPLTLQALSGHPV 61 Query: 74 ITEIT-----GSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFP 128 T++ ++ H+ELA ADL+L+ PATA+ ++++ G+ + +TT+V Sbjct: 62 HTDLLDPAAEAAMGHIELA----RWADLVLIAPATADLMARLVQGVANDLLTTLVLAT-- 115 Query: 129 HIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEIVY 182 I +APAM+++M++ + N E L++ G GP + G ++ +E+ Sbjct: 116 DAQIALAPAMNQAMWRDTATQANAELLRQRGFHLFGPAAGSQACGDVGLGRMLEAEELAQ 175 Query: 183 RVIKKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIR 242 R + L G VLITAG T+E IDP+R+ITN SSGKMG ALAE A GA VTL+ Sbjct: 176 RAADCFQRQALTGVHVLITAGPTQENIDPVRYITNHSSGKMGFALAEAAVEAGARVTLV- 234 Query: 243 TRGSVKSFVEN---QIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIK 299 G V + +++V + +ML A E + D++I +AAV+D++P++ A K+K Sbjct: 235 -TGPVHLPTPDRVQRVDVVSARDMLAACEAAM---PCDLLIASAAVADYRPEVVAAHKLK 290 Query: 300 SD----KSITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLV 355 D + + L+LV NP I+ + + + F VGF AET E L+ A ++++ DL+ Sbjct: 291 KDPTSGEGLLLQLVRNPDILATLAQREDRPFSVGFAAET--ENLLDYAARKLKDKNLDLI 348 Query: 356 IGNTLE----AFGSEESKVVIVGKD 376 + N + F S+E+ + ++ +D Sbjct: 349 VANDVANPSIGFNSDENAITVIDRD 373 >pir||D69878 pantothenate metabolism flavoprotein dfp homolog yloI - Bacillus subtilis >gi|2337799|emb|CAA74260.1| (Y13937) putative Dfp protein [Bacillus subtilis] >gi|2633942|emb|CAB13443.1| (Z99112) similar to pantothenate metabolism flavoprotein [Bacillus subtilis] Length = 406 Score = 196 bits (494), Expect = 3e-49 Identities = 147/408 (36%), Positives = 213/408 (52%), Gaps = 40/408 (9%) Query: 16 LVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVIT 75 L + ++L + G IA + L +L++ GA V +M+ SA + + P + + + V T Sbjct: 2 LNNRNVLLCVSGGIAVYKACALTSKLVQAGANVKVIMTESACRFVSPLTFQALSRHEVYT 61 Query: 76 EI-----TGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHI 130 + I H++ A + ADLI+V PATAN I K+A GI D +TT + A Sbjct: 62 DTFKEQNPSVISHIDAA----DWADLIIVAPATANVIGKLANGIADDMLTTTLLAATA-- 115 Query: 131 PIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEE------GKAKVATIDEIVYRV 184 P+ IAPAM+ MY HP V+ NI L + G FI P GK ++ + IV Sbjct: 116 PVWIAPAMNVHMYDHPAVKRNISVLYQDGYCFIEPSEGYLACGYVGKGRLEEPENIVKLA 175 Query: 185 IKKLHPKT---LEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLI 241 K +T LEGK V+ITAG TRE IDP+RF TN S+GKMG ALAE A GA V LI Sbjct: 176 EKHFAEETSAPLEGKHVVITAGPTREAIDPVRFFTNKSTGKMGYALAEAAVQLGARVILI 235 Query: 242 RTRGS------VKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAK 295 S + F+ Q + E +L + D+VI AAV+DF PK Sbjct: 236 SGPVSLDQPKGLAEFIPVQSAADMREAVLSVYDAS------DIVIKTAAVADFTPKTVFD 289 Query: 296 EKI-KSDKSITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDL 354 K+ K D +TLEL I++++ E + + LVGF AET + + A+K++ + DL Sbjct: 290 HKMKKQDGGMTLELKRTVDILKELGEKKKEQILVGFAAET--QDIEHYARKKLAAKNLDL 347 Query: 355 VIGNTLEA----FGSEESKVVIVGKD-FVKELPRMKKRELAERIWDEI 397 ++ N ++A FG++ + V I KD +ELP M K +++ I EI Sbjct: 348 IVANDVKANGAGFGADTNIVTIFFKDGHKRELPIMSKLDVSFEILQEI 395 >emb|CAC12018.1| (AL445065) DNA/pantothenate metabolism flavoprotein related protein [Thermoplasma acidophilum] Length = 394 Score = 193 bits (485), Expect = 3e-48 Identities = 121/310 (39%), Positives = 183/310 (59%), Gaps = 7/310 (2%) Query: 13 SRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNP 72 SR L G +++A GSI+ L R+L R GA+V MS S+ ++ P M +A+ Sbjct: 10 SRMLEGYTVIVATSGSISIYRIPDLVRDLRREGADVIVGMSQSSAAMVSPEVMRWASERD 69 Query: 73 VITEITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPH-IP 131 V+TEITG IEH+ L E+ K ++L+ PA+ NT+ K+A GI D+ + + AF H + Sbjct: 70 VVTEITGRIEHISLFTENREK-KILLIAPASYNTLGKMANGITDSVPSLFFSFAFGHGVK 128 Query: 132 IMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVATIDEIVYRVIKKLHPK 191 ++APAMH SM ++PI NIEKL+ LGV F+ P ++ KAK+ I+ V + +H K Sbjct: 129 TVVAPAMHRSMMENPINLANIEKLRSLGVNFVDPIYDDEKAKLNGNGAILDGVCRSVH-K 187 Query: 192 TLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAE--VTLIRTRGSVKS 249 L GK++LI +G E IDP+R ITNA SG GV LA A GA L T+ + Sbjct: 188 DLAGKKILIISGRGEEPIDPVRSITNAGSGFTGVWLARNAYRMGASSITYLGNTQFDLPG 247 Query: 250 FVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSDKSITLELV 309 +V+ +E T+++ +E+ ++ YD VI+ AA+ DFK ++++K SD+ + + L Sbjct: 248 YVK-YVEAHTIDDFEKKTMDEI-EEGYDAVIVNAALPDFKVAERSQKKYSSDQPLRITLN 305 Query: 310 PNPKIIRKIK 319 P KII KI+ Sbjct: 306 PREKIIYKIR 315 >sp|P44953|DFP_HAEIN DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOMOLOG >gi|1075104|pir||G64104 pantothenate metabolism flavoprotein dfp homolog HI0953 - Haemophilus influenzae (strain Rd KW20) >gi|1573978|gb|AAC22614.1| (U32776) DNA/pantothenate metabolism flavoprotein (dfp) [Haemophilus influenzae Rd] Length = 400 Score = 190 bits (479), Expect = 2e-47 Identities = 139/403 (34%), Positives = 223/403 (54%), Gaps = 32/403 (7%) Query: 15 KLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVI 74 KL GK IV+ I G IAA + ++L R L + AEV V++P+A + + P ++ +GN V Sbjct: 2 KLNGKHIVVGITGGIAAYKTIELIRLLRKAEAEVRVVLTPAAAEFVTPLTLQAISGNAVS 61 Query: 75 TEITG-----SIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPH 129 + ++ H+ELA AD I++ PA+A+ I+++ G+ + ++T+ + Sbjct: 62 QSLLDPQAELAMGHIELA----KWADAIIIAPASADFIARLTIGMANDLLSTICLAT--N 115 Query: 130 IPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEIVYR 183 PI +APAM++ MY I ++N+ L+ G+E IGP + GK +++ +EI Sbjct: 116 APIFLAPAMNQQMYHQSITQQNLTTLQTRGIELIGPNSGFQACGDMGKGRMSEPEEIFTA 175 Query: 184 VIKKLHPKT-LEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIR 242 + K L+G V ITAG TRE IDP+R+I+N SSGKMG A+AE RGA VTLI Sbjct: 176 LSDFFSQKQDLQGLNVSITAGPTREAIDPVRYISNHSSGKMGFAIAEAFAKRGANVTLI- 234 Query: 243 TRGSVKSFVE---NQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKI- 298 G V N+I V + +EM A E K + + I AAV+D++ A++KI Sbjct: 235 -AGPVNLTTPKNVNRINVISAQEMWQASLESAVKNQ--IFIGCAAVADYRVTEVAEQKIK 291 Query: 299 KSDKSITLELVPNPKIIRKIKEIQSD-VFLVGFKAETSMEKLISEAKKQIESAGSDLVIG 357 KS I+++L+ NP II + +++ F VGF AET + + AK ++E D++ Sbjct: 292 KSGDEISIKLIKNPDIISDVGHLKTHRPFTVGFAAET--QNVDDYAKDKLERKNLDMICA 349 Query: 358 NTL---EAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEI 397 N + + F ++E+ + + K+ K+L K ELA + +EI Sbjct: 350 NDVSGGQVFNADENALQLFWKNGHKKLSLKSKVELAADLVNEI 392 >gb|AAD21550.1| (AF088896) pantothenate metabolism flavoprotein [Zymomonas mobilis] Length = 417 Score = 184 bits (462), Expect = 2e-45 Identities = 131/409 (32%), Positives = 214/409 (52%), Gaps = 40/409 (9%) Query: 16 LVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVIT 75 L GK+I+L I GSIAA++ + R + A++ +++ I P A+ +GNPV Sbjct: 5 LNGKRILLVISGSIAAIKAPDIIRLFRKKKADIRCLITKGGANFITPLALASLSGNPVAQ 64 Query: 76 EI-----TGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHI 130 ++ SI H+ LA E AD+I+V PA+A+ ISK+A G+ + +TVV A Sbjct: 65 DMWDESEEASIRHIRLARE----ADMIIVAPASADFISKMAHGLANDLASTVVLAA--DS 118 Query: 131 PIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEIVYRV 184 PI++APAM+ M+ H + NI +LK G+ F+ P E G ++A ++I+ Sbjct: 119 PILVAPAMNHRMWHHSATQRNIHQLKSDGISFVDPEAGAMACGETGIGRLAAPEDILLSA 178 Query: 185 ----IKKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTL 240 ++ + + L+ + ++TAG T E IDP+R++ N SSGK G A+AE + GA+VTL Sbjct: 179 ESLFAEEQNHQFLKNRHFIVTAGPTHEPIDPVRYLANRSSGKQGFAIAEALQKLGAKVTL 238 Query: 241 IRTRGSVKSFVENQIE---VETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEK 297 + G V +++E VET EM A+E L D I AAV+D++ + Sbjct: 239 V--TGPVYQNTPDRVERVNVETAIEMEKAVENALPA---DGAIFTAAVADWRFNYSPSKY 293 Query: 298 IKSDKSITLELVPNPKIIRKI--KEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLV 355 K L + P+I+ I ++I +VGF AE+ E L+ AK +++ G D + Sbjct: 294 KKGRSEPELIPIEKPEILSNISKRKIDRPSLVVGFAAES--ENLLENAKVKLQQKGCDWI 351 Query: 356 IGNTL-------EAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEI 397 I N + A G + +K+ I ++ P + K+E+A R+ +I Sbjct: 352 IANPVIESEDAPSAMGGDYNKIFIASHAGIENWPLLSKKEVASRLASKI 400 >emb|CAB93357.1| (AL357523) putative flavoprotein homologue (partial) [Streptomyces coelicolor A3(2)] Length = 376 Score = 184 bits (462), Expect = 2e-45 Identities = 126/370 (34%), Positives = 198/370 (53%), Gaps = 29/370 (7%) Query: 5 IKLIYATKSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYA 64 ++ Y ++ + K+VL + G IAA + +L R L G EV V + SA + Sbjct: 17 VRARYPSRGETVDKPKVVLGVSGGIAAYKACELLRRLTESGHEVRVVPTASALHFVGAAT 76 Query: 65 MEFATGNPVITEITGSIE---HVELAGEHENKADLILVCPATANTISKIACGIDDTPVTT 121 +GNPV TE+ + HV + G+H ADL++V PATA+ ++K A G+ D +T Sbjct: 77 WSALSGNPVSTEVWDDVHEVPHVRI-GQH---ADLVVVAPATADMLAKAAHGLADDLLTN 132 Query: 122 VVTTAFPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKV- 174 + TA P++ APAMH M++HP +EN+ L++ G I P + + GK ++ Sbjct: 133 TLLTA--RCPVVFAPAMHTEMWEHPATQENVAALRRRGAVVIEPAVGRLTGVDTGKGRLP 190 Query: 175 --ATIDEIVYRVIKK-LHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEA 231 I E+ RV+ + + L G+ V+++AG TRE +DP+RF+ N SSGK G ALA A Sbjct: 191 DPGEIFEVCRRVLARGVREPDLAGRHVVVSAGGTREPLDPVRFLGNRSSGKQGYALARTA 250 Query: 232 EFRGAEVTLIRTRGSVKSFV-ENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKP 290 RGA VTL+ S+ + + V T E+ A+ D V+MAAAV+DF+P Sbjct: 251 AARGARVTLVAANASMPDPAGVDVVPVGTAVELREAVLRAAADA--DAVVMAAAVADFRP 308 Query: 291 KIKAKEKIK---SDKSITLELVPNPKIIRKIKE--IQSDVFLVGFKAETSMEKLISEAKK 345 A KIK + + LV NP I+ +I + +S +VGF AET + +++ + Sbjct: 309 ATYATGKIKKKDDQEPAPITLVRNPDILAEISQTRARSGQVVVGFAAET--DDVLANGRV 366 Query: 346 QIESAGSDLV 355 +++ G DL+ Sbjct: 367 KLKRKGCDLL 376 >sp|P71661|DFP_MYCTU DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOMOLOG >gi|7449274|pir||E70899 pantothenate metabolism flavoprotein dfp - Mycobacterium tuberculosis (strain H37RV) >gi|1542899|emb|CAB02174.1| (Z80108) dfp [Mycobacterium tuberculosis] Length = 418 Score = 173 bits (433), Expect = 4e-42 Identities = 127/413 (30%), Positives = 213/413 (50%), Gaps = 38/413 (9%) Query: 15 KLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVI 74 K + K++++ + G IAA + + R+L V + + SA + + E +G PV Sbjct: 5 KRIPKQVIVGVSGGIAAYKACTVVRQLTEASHRVRVIPTESALRFVGAATFEALSGEPVC 64 Query: 75 TEITG---SIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIP 131 T++ ++ HV L +ADL++V PATA+ +++ A G D +T + TA P Sbjct: 65 TDVFADVPAVPHVHLG----QQADLVVVAPATADLLARAAAGRADDLLTATLLTA--RCP 118 Query: 132 IMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEI--VYR 183 ++ APAMH M+ HP +N+ L++ G + P + G ++ +EI + + Sbjct: 119 VLFAPAMHTEMWLHPATVDNVATLRRRGAVVLEPATGRLTGADSGAGRLPEAEEITTLAQ 178 Query: 184 VIKKLH---PKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTL 240 ++ + H P L G+++L+TAG TRE IDP+RFI N SSGK G A+A A RGA+VTL Sbjct: 179 LLLERHDALPYDLAGRKLLVTAGGTREPIDPVRFIGNRSSGKQGYAVARVAAQRGADVTL 238 Query: 241 I--RTRGSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKI 298 I T G V + V + +++ A+ + DV++MAAAV+DF+P A KI Sbjct: 239 IAGHTAGLVDPAGVEVVHVSSAQQLADAVSKHAPTA--DVLVMAAAVADFRPAQVATAKI 296 Query: 299 KS--DKSITLELVPNPKII------RKIKEIQSDVFLVGFKAET--SMEKLISEAKKQIE 348 K + T+EL+ N ++ R ++ + +VGF AET + ++ A+ ++ Sbjct: 297 KKGVEGPPTIELLRNDDVLAGVVRARAHGQLPNMRAIVGFAAETGDANGDVLFHARAKLR 356 Query: 349 SAGSDLVIGNTL---EAFGSEESKVVIVGKDFVKE-LPRMKKRELAERIWDEI 397 G DL++ N + AF + + ++ D + L K +A RI D I Sbjct: 357 RKGCDLLVVNAVGEGRAFEVDSNDGWLLASDGTESALQHGSKTLMASRIVDAI 409 >sp|P24285|DFP_ECOLI DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN >gi|7430385|pir||A65165 pantothenate metabolism flavoprotein dfp - Escherichia coli (strain K-12) >gi|1790070|gb|AAC76663.1| (AE000441) flavoprotein affecting synthesis of DNA and pantothenate metabolism [Escherichia coli K12] Length = 430 Score = 173 bits (433), Expect = 4e-42 Identities = 127/405 (31%), Positives = 216/405 (52%), Gaps = 34/405 (8%) Query: 16 LVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVIT 75 L GKKIVL + G IAA + +L R L GA+V M+ +A I P +++ +G PV Sbjct: 27 LAGKKIVLGVSGGIAAYKTPELVRRLRDRGADVRVAMTEAAKAFITPLSLQAVSGYPVSD 86 Query: 76 EIT-----GSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHI 130 + ++ H+EL ADL+++ PATA+ I+++A G+ + V+T+ Sbjct: 87 SLLDPAAEAAMGHIELG----KWADLVILAPATADLIARVAAGMANDLVSTICLAT--PA 140 Query: 131 PIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEIVYRV 184 P+ + PAM++ MY+ + N+E L G+ GP + G ++ IV Sbjct: 141 PVAVLPAMNQQMYRAAATQHNLEVLASRGLLIWGPDSGSQACGDIGPGRMLDPLTIVDMA 200 Query: 185 IKKLHP-KTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIRT 243 + P L+ ++ITAG TRE +DP+R+I+N SSGKMG A+A A RGA VTL+ Sbjct: 201 VAHFSPVNDLKHLNIMITAGPTREPLDPVRYISNHSSGKMGFAIAAAAARRGANVTLVSG 260 Query: 244 RGSVKS--FVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSD 301 S+ + FV+ +++V T EM A+ + ++ ++ I AAV+D++ A EKIK Sbjct: 261 PVSLPTPPFVK-RVDVMTALEMEAAVNASV--QQQNIFIGCAAVADYRAATVAPEKIKKQ 317 Query: 302 KS----ITLELVPNPKIIRKIKEIQSD-VFLVGFKAETSMEKLISEAKKQIESAGSDLVI 356 + +T+++V NP I+ + ++ ++VGF AET+ + + K+ ++ DL+ Sbjct: 318 ATQGDELTIKMVKNPDIVAGVAALKDHRPYVVGFAAETNNVEEYARQKRIRKNL--DLIC 375 Query: 357 GNTL----EAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEI 397 N + + F S+ + + + +D K LP +K L + + DEI Sbjct: 376 ANDVSQPTQGFNSDNNALHLFWQDGDKVLPLERKELLGQLLLDEI 420 >gb|AAA61992.1| (L10328) dfp (CG Site No. 18430) [Escherichia coli] Length = 430 Score = 172 bits (432), Expect = 5e-42 Identities = 127/405 (31%), Positives = 215/405 (52%), Gaps = 34/405 (8%) Query: 16 LVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVIT 75 L GKKIVL + G IAA + +L R L GA+V M+ +A I P +++ +G PV Sbjct: 27 LAGKKIVLGVSGGIAAYKTPELVRRLRDRGADVRVAMTEAAKAFITPLSLQAVSGYPVSD 86 Query: 76 EIT-----GSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHI 130 + ++ H+EL ADL+++ PATA+ I+++A G+ + V+T+ Sbjct: 87 SLLDPAAEAAMGHIELG----KWADLVILAPATADLIARVAAGMANDLVSTICLAT--PA 140 Query: 131 PIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEIVYRV 184 P+ + PAM++ MY+ + N+E L G+ GP + G + IV Sbjct: 141 PVAVLPAMNQQMYRAAATQHNLEVLASRGLLIWGPDSGSQACGDIGPGRXXDPLTIVDMA 200 Query: 185 IKKLHP-KTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIRT 243 + P L+ ++ITAG TRE +DP+R+I+N SSGKMG A+A A RGA VTL+ Sbjct: 201 VAHFSPVNDLKHLNIMITAGPTREPLDPVRYISNHSSGKMGFAIAAAAARRGANVTLVSG 260 Query: 244 RGSVKS--FVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSD 301 S+ + FV+ +++V T EM A+ + ++ ++ I AAV+D++ A EKIK Sbjct: 261 PVSLPTPPFVK-RVDVMTALEMEAAVNASV--QQQNIFIGCAAVADYRAATVAPEKIKKQ 317 Query: 302 KS----ITLELVPNPKIIRKIKEIQSD-VFLVGFKAETSMEKLISEAKKQIESAGSDLVI 356 + +T+++V NP I+ + ++ ++VGF AET+ + + K+ ++ DL+ Sbjct: 318 ATQGDELTIKMVKNPDIVAGVAALKDHRPYVVGFAAETNNVEEYARQKRIRKNL--DLIC 375 Query: 357 GNTL----EAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEI 397 N + + F S+ + + + +D K LP +K L + + DEI Sbjct: 376 ANDVSQPTQGFNSDNNALHLFWQDGDKVLPLERKELLGQLLLDEI 420 >pir||H82842 DNA/pantothenate metabolism flavoprotein XF0149 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9104938|gb|AAF82962.1|AE003868_8 (AE003868) DNA/pantothenate metabolism flavoprotein [Xylella fastidiosa] Length = 409 Score = 171 bits (430), Expect = 9e-42 Identities = 133/407 (32%), Positives = 221/407 (53%), Gaps = 42/407 (10%) Query: 14 RKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPV 73 R L G++++L + G IAA + ++L R L G +V M+ SA + + P + + +G Sbjct: 8 RSLNGQRLLLCVSGGIAAYKSLELVRRLCGAGVQVQVAMTASAQQFVTPLSFQALSGQST 67 Query: 74 ITEI-TGSIE----HVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTV--VTTA 126 T + G+ E H+ELA A+ +L+ PA+A+ I+++A G+ D VTT+ TTA Sbjct: 68 RTTLWDGNAEQAMGHIELA----RWAECVLIAPASADVIARLAHGLADDLVTTLCLATTA 123 Query: 127 FPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPR---IEEGKAKVATIDE---I 180 ++I PAM+ +M+ HP + N+ L GV+ IGP + EG + + + E I Sbjct: 124 L----LIICPAMNHNMWLHPATQANVAMLVGRGVQVIGPEDGPLAEGVSGLGRMSEPEAI 179 Query: 181 VYRVIKKLHPKTLEG-----KRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRG 235 V +++ + P + G +R++I+AG T E +DP+R++ N SSGKMG ALA A G Sbjct: 180 VAALVQGVSPAPVHGGLFHGQRIVISAGPTFEDLDPVRYLGNRSSGKMGFALASAAVSHG 239 Query: 236 AEVTLIRTRGSVKSFVE---NQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKI 292 AEV L+ G V +++V + +M A+ L+ DV I AAAV+D+ PK Sbjct: 240 AEVVLV--AGPVYQPTPPGVTRVDVRSAAQMRDAV---LSAFPADVYIGAAAVADYAPKS 294 Query: 293 KAKEKI-KSDKSITLELVPNPKIIRKIKEIQSDV-FLVGFKAETSMEKLISEAKKQIESA 350 +KI KS +++TLELV I+ ++ +++ F+VGF AET + A+ ++ + Sbjct: 295 VLPQKIKKSGQTLTLELVRTQDILSEVAAQTANLKFVVGFAAET--HDVERYARGKLAAK 352 Query: 351 GSDLVIGNTL----EAFGSEESKVVIVGKDFVKELPRMKKRELAERI 393 DL+I N + F S+++ V + + + K ELAER+ Sbjct: 353 HLDLIIANQVGIVGNGFESDDNAVTVYWQGGERVFASCSKVELAERL 399 >pir||H75501 DNA/pantothenate metabolism flavoprotein - Deinococcus radiodurans (strain R1) >gi|6458275|gb|AAF10158.1|AE001916_4 (AE001916) DNA/pantothenate metabolism flavoprotein [Deinococcus radiodurans] Length = 422 Score = 167 bits (419), Expect = 2e-40 Identities = 132/405 (32%), Positives = 209/405 (51%), Gaps = 39/405 (9%) Query: 22 VLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITEITGSI 81 ++ + GS+AAV+ R L GA + + +A I P ++ A V T+ T Sbjct: 19 LVIVGGSMAAVKAPTALRRLREGGASTAVIATRAALAFITPLSLATAGNCEVATDETWFA 78 Query: 82 -----EHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIPIMIAP 136 +H+ LA +A + +V A+A ++ A G DT T + +A + + P Sbjct: 79 PQPIAQHLSLA-----RARVTVVLGASAELLAAAAHGHADTLATATLLSAEGQV--LWVP 131 Query: 137 AMHESMYKHPIVRENIEKLKKLGVEFIGPRIE--------EGKAKVATIDEIVYRVIKKL 188 AM+E M+ HP V+ N E+L+ G F+GP G ++A + I R + L Sbjct: 132 AMNERMWLHPAVQANAERLRGWGHLFLGPETGAFGTPGEGSGTGRMAEPEAIAARALALL 191 Query: 189 H---------PKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVT 239 + P+ L G +V+++AG TREY+DP+RFI+N SSGKMG A+AEEA RGAEV Sbjct: 192 NEQDAEAEAAPQDLAGLKVVVSAGPTREYLDPVRFISNPSSGKMGFAVAEEARTRGAEVV 251 Query: 240 LIRTRGSVKSFVENQ-IEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKI-KAKEK 297 L+ ++ Q + +ET EM AI E D+V+M AA++D++ K++++ Sbjct: 252 LVTGPVNLPDLSGVQTVRIETALEMQAAIME--AAGDADMVVMTAAIADYRAAAPKSEKE 309 Query: 298 IKSDKSITLELVPNPKIIRKIKEIQS---DVFLVGFKAETSMEKLISEAKKQIESAGSDL 354 K+ +T+ L PNP I+ + Q+ LVGF ET + K Q ++A L Sbjct: 310 AKTPGDVTIHLTPNPDILAGLGAEQAAHPGRVLVGFAMETHAGVERAALKAQRKNADFIL 369 Query: 355 VIGNTLE--AFGSEESKVVIVGKDFV-KELPRMKKRELAERIWDE 396 + T E AFG ++++V +V D + PR+ KRE+A R+ DE Sbjct: 370 LNYPTREGTAFGGDDNQVTLVRADGTHADWPRISKREVARRLLDE 414 >sp|P73881|DFP_SYNY3 DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOMOLOG >gi|7449262|pir||S75082 pantothenate metabolism flavoprotein dfp homolog sll0250 - Synechocystis sp. (strain PCC 6803) >gi|1653027|dbj|BAA17944.1| (D90910) pantothenate metabolism flavoprotein [Synechocystis sp.] Length = 402 Score = 166 bits (415), Expect = 5e-40 Identities = 124/407 (30%), Positives = 212/407 (51%), Gaps = 31/407 (7%) Query: 18 GKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVI--T 75 GK+I++ + G IAA + ++ +L + GAEV +++ A K + P +P Sbjct: 4 GKRILIGVGGGIAAYKICEVVSQLFQQGAEVRVILTAEAEKFVTPLTFTTLARHPAYGDA 63 Query: 76 EITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIPIMIA 135 + I H L + AD+ L+ P TA+T++K+ G D ++ V + PI++A Sbjct: 64 DFWQPIHHRPLHIDLGEWADIFLIAPLTAHTLAKLGHGFADDLLSNTVLAS--SCPILLA 121 Query: 136 PAMHESMYKHPIVRENIEKLKKLG---VEFIGPR------IEEGKAKVATIDEIVYRVIK 186 PAM+ M++ V+ N+++L LG + P G ++A +I++R+ Sbjct: 122 PAMNTDMWEQEAVQRNLQQL--LGDRRYHLLAPNGGLLACDRRGVGRLAEPAQIMHRLQA 179 Query: 187 KLHP---KTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIRT 243 L + L GKR+LITAG T+EY+D +RFI N S+GKMG+ALA+ A RGA VTLI Sbjct: 180 LLFTGGQEDLRGKRILITAGGTQEYLDAVRFIGNPSTGKMGLALAQSAGDRGARVTLIHG 239 Query: 244 RGSVKSFVENQIEVETV--EEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKI-KS 300 I + V E+M A+ ++ D ++MAAAV+D KP KI K Sbjct: 240 PIGDLPIPMGVISMAVVNAEQMEQALAQQAPLA--DWIVMAAAVADVKPAQTWTGKIAKQ 297 Query: 301 DKSITLELVPNPKIIRKI-KEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGNT 359 D +L L P P +I ++ K+ + LVGF A+ +++ AK++++ D+++ N Sbjct: 298 DLPDSLPLAPVPDLIAQVSKQKRPHQLLVGFAAQAG--DIVTPAKEKLQRKNLDVIVANP 355 Query: 360 LE----AFGSEESKVVIVGKDFVK-ELPRMKKRELAERIWDEIEKKI 401 ++ FG++ ++ VI+ + + + K +A RIW + ++I Sbjct: 356 IDQPQSGFGTDSNQAVIIDRHGSQTAIAPCSKLAMAHRIWQYLLERI 402 >gb|AAB97414.1| (AF042096) panthotenate metabolism flavoprotein [Bradyrhizobium japonicum] Length = 444 Score = 143 bits (356), Expect = 4e-33 Identities = 125/420 (29%), Positives = 199/420 (46%), Gaps = 44/420 (10%) Query: 16 LVGKKIVLAIPGSIAAVECVKLARELIR--HGAEVHAVM---SPSATKII--HPYAMEFA 68 L + L I G IA ++ + L R L H + S S T ++ P+ M + Sbjct: 26 LAEASVTLIIGGGIARLKSLDLIRRLKERCHRGPLRTDQTRPSSSVTPLVGQRPFRMSAS 85 Query: 69 TGNPVITEITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFP 128 I H+ LA + DLI+V PATA+ +SK+A G D + ++ Sbjct: 86 IPTCPIPRSEFDAGHIRLARD----CDLIVVAPATADLMSKMANGHADDLASAILLAT-- 139 Query: 129 HIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPR----IEEGKAKVATIDEIVY-- 182 + +++APAM+ M+ + R N+ +L++ GV IGP E G+A + + E + Sbjct: 140 NRKVLLAPAMNPLMWNNAATRRNVAQLQRDGVVLIGPNSGEMAEAGEAGIGRMSEALEIA 199 Query: 183 ----RVIKKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEV 238 R+++ P+ L GKRVLITAG T E IDP+R+I N SSGK G A+A A+ GAEV Sbjct: 200 AAAERLLRPPVPRPLAGKRVLITAGPTHEPIDPVRYIANRSSGKQGFAIAAAAQAAGAEV 259 Query: 239 TLIRTRGSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVS-DFKPKIKAKEK 297 L+ G V + V+ VE +E+ D+ I S D++ + ++K Sbjct: 260 ILV--SGPVDLGDPQGVTVKHVESARQMLEQVQAALPADIAIFQPPRSPDWRVANEGEQK 317 Query: 298 IKSDKS--ITLELVPNPKIIRKIKEI--QSDVFLVGFKAETSMEKLISEAKKQIESAGSD 353 +K + L+LV NP I+ I ++ + L+GF AET E LI AK ++ G D Sbjct: 318 LKKTSAGMPPLQLVENPDILATIAKLTDKRPPLLIGFAAET--EHLIDNAKTKLARKGCD 375 Query: 354 LVIGNTLE----AFGSEESKVVIV--------GKDFVKELPRMKKRELAERIWDEIEKKI 401 ++ N + G + + V ++ G+ V P M K ++A + I K + Sbjct: 376 WIVANDVSPATGVMGGDRNTVHLISRKNGEKNGEIAVDSWPAMTKEQVATELIAHIVKSV 435 >pir||E71889 pantothenate metabolism flavoprotein dfp homolog HP0841 - Helicobacter pylori (strain J99) >gi|4155346|gb|AAD06359.1| (AE001508) PANTOTHENATE METABOLISM FLAVOPROTEIN [Helicobacter pylori J99] Length = 425 Score = 134 bits (334), Expect = 2e-30 Identities = 115/417 (27%), Positives = 198/417 (46%), Gaps = 39/417 (9%) Query: 14 RKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPV 73 R L K+++L + GSIAA + ++L R L + GA + VMS A K I P + E + + V Sbjct: 12 RLLENKRVLLLVSGSIAAYKSLELVRLLFKSGASIQVVMSKGAQKFIKPLSFEALSHHKV 71 Query: 74 ITEITGSIEHVELAGEHEN------KADLILVCPATANTISKIACGI-DDTPVTTVVTTA 126 + + + H N ADL++ P +AN++SKIA + D+T T + A Sbjct: 72 LHDRNEKWYYNHQNKLHHNHIACAASADLLIFAPLSANSLSKIAHALADNTISATFLACA 131 Query: 127 FPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPR------IEEGKAKVATIDEI 180 P I +AP+M+ +M PI++ N+++LK + + +G +A EI Sbjct: 132 SPKI---LAPSMNTNMLNSPIIQSNLKRLKDSNHIILDTQNALLACNTKGDGAMAEPLEI 188 Query: 181 VYRVIKK-LHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVT 239 +++ + L E + V++ GA+ E ID +R I+N SSG ALA F+GA+VT Sbjct: 189 LFKATQTLLKDAYFENREVIVMGGASVEKIDSVRVISNLSSGIQASALALALYFKGAKVT 248 Query: 240 LIRTR------GSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIM-AAAVSDFKPKI 292 LI + + S + + + + E L + L K ++ AA+SD+ PK Sbjct: 249 LIASNFPTPLPKEIASVLVS--DTASYENALNEAAKNLQKHALKPLLFNLAAISDYLPKT 306 Query: 293 KAKEKIKSD---KSITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAK---KQ 346 K+K +++ +E V N ++ + Q +GFKAE + I A+ K Sbjct: 307 SFNHKLKKSELGETLNVECVQNKDLLASVNPNQ--FVKIGFKAEDDQQNAIKNAQNLLKP 364 Query: 347 IESAGSDLVIG-----NTLEAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEIE 398 + G D + FGS ++++ + +++P M K E + +I D I+ Sbjct: 365 SQDNGKDCSVAALNLIKDSRPFGSLDNELWLFSHKKTQKIPSMNKLEASFKILDFIK 421 >pir||A64625 pantothenate metabolism flavoprotein dfp homolog HP0841 - Helicobacter pylori (strain 26695) >gi|2313973|gb|AAD07888.1| (AE000595) pantothenate metabolism flavoprotein (dfp) [Helicobacter pylori 26695] Length = 425 Score = 133 bits (332), Expect = 3e-30 Identities = 118/417 (28%), Positives = 201/417 (47%), Gaps = 39/417 (9%) Query: 14 RKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPV 73 R L K+++L + GSIAA + ++L R L + GA + VMS A K I P + E + + V Sbjct: 12 RLLENKRVLLLVSGSIAAYKSLELVRLLFKSGASIQVVMSKGAKKFIKPLSFEALSHHKV 71 Query: 74 ITEITGSIEHVELAGEHEN------KADLILVCPATANTISKIACGIDDTPVT-TVVTTA 126 + + + H N ADL++ P + N++SKIA + D V+ T + A Sbjct: 72 LHDRNEKWYYNHQNALHHNHIACAANADLLIFAPLSTNSLSKIAHALADNIVSATFLACA 131 Query: 127 FPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPR------IEEGKAKVATIDEI 180 P I +AP+M+ +M PI + N+++LK + + +G +A EI Sbjct: 132 SPKI---LAPSMNTNMLNSPITQSNLKRLKDSNHIILDTKNALLACDTKGDGAMAEPLEI 188 Query: 181 VYRVIKK-LHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVT 239 +++ + L E + V++ GA+ E ID +R I+N SSG ALA F+GA+VT Sbjct: 189 LFKAAQTLLKDAYFENREVIVMGGASIEKIDSVRTISNLSSGIQASALALALYFKGAKVT 248 Query: 240 LIRTR------GSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIM-AAAVSDFKPKI 292 LI + + S + + + + E L + L K ++ AA+SD+ PK Sbjct: 249 LIASNFPTPLPKEITSVLVS--DTASYENALNSAANNLQKHALKPLLFNLAAISDYVPKT 306 Query: 293 KAKEKIKSD---KSITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAK---KQ 346 K+K +++ +E V N ++ I Q +GFKAE + + I A+ K Sbjct: 307 SFNYKLKKSEIGETLNIECVQNKDLLVSINPNQ--FVKIGFKAEDNQQNAIKNAQNLLKP 364 Query: 347 IESAGSD--LVIGNTLE---AFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEIE 398 + G D +V N ++ FGS E+++ + +++P M K E + +I D I+ Sbjct: 365 FKDNGKDCSVVALNLIKDSRPFGSLENELWLFSHHKTQKIPSMNKLEASFKILDFIK 421 >pir||F81354 DNA /pantothenate metabolism flavoprotein Cj0822 [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968268|emb|CAB73087.1| (AL139076) DNA /pantothenate metabolism flavoprotein [Campylobacter jejuni] Length = 384 Score = 125 bits (310), Expect = 1e-27 Identities = 115/396 (29%), Positives = 196/396 (49%), Gaps = 29/396 (7%) Query: 19 KKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITEIT 78 K I+LAI GSIA + +L + G V ++S K + E A + V+ E Sbjct: 2 KTILLAISGSIAFYKSYELISLFKKEGFRVKVLLSNGLLKFASKMSFE-ALVDEVLCEEN 60 Query: 79 GSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIPIMIAPAM 138 S ++ DL+L PA+ N+I+K+A GI D + A + P++IAPA Sbjct: 61 ESWQNSNNHIAFSKDVDLVLFTPASVNSINKLAFGIADNLFIQTLIAA--NKPLIIAPAA 118 Query: 139 HESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEIVYRVIKK--LHP 190 + +M+ H + +++ LK+ I P +EG +A + +I + + K+ L Sbjct: 119 NTNMFHHFSTQNSLKILKENKALIIEPICKVLACKDEGVGALAEVKDI-FNITKRELLKE 177 Query: 191 KTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIRTRGSVKSF 250 K K V+IT G TRE ID +R ++N SSGKM A+A+ F GA V L+ SV+ Sbjct: 178 KFWCNKSVVITGGGTRERIDDVRCVSNFSSGKMAKAIADAFYFLGARVKLL---SSVEFD 234 Query: 251 VENQI-EVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSD---KSITL 306 ++ + E+ +++ +++ L+ +D +IM AAVSDF P+ K KIK + + + L Sbjct: 235 TPYELCKFESSKDLKELLDKNLS---HDFLIMTAAVSDFIPQ-SVKGKIKKNEHLQGLNL 290 Query: 307 ELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGNTLEA---F 363 L N +++ K Q +GFK E + + AKK ++ D+V N ++ F Sbjct: 291 HLSLNEDLLKTCK-FQGK--KIGFKMEFDSQNALENAKKSLKDKQLDMVCLNIIDQKNYF 347 Query: 364 GSEESKVVIVGKDFVKELPRMKKRELAERIWDEIEK 399 GS+++++ + + + K +LA + EK Sbjct: 348 GSDQNELYFITLNNENKSTLQSKEKLAFELVKWCEK 383 >sp|Q54433|DFP_STRMU DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOMOLOG >gi|1216490|gb|AAC44502.1| (U48885) DNA/pantothenate metabolism flavoprotein [Streptococcus mutans] Length = 145 Score = 94.0 bits (230), Expect = 3e-18 Identities = 55/146 (37%), Positives = 83/146 (56%), Gaps = 9/146 (6%) Query: 19 KKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITEIT 78 KKI+LA+ GSIAA + L+ +L + G V+ M+ +A + I P ++ + NPV + + Sbjct: 3 KKILLAVSGSIAAYKAADLSHQLTKLGYHVNVFMTNAAKQFIPPLTLQVLSKNPVYSNVM 62 Query: 79 GS-----IEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIPIM 133 I H+ LA +ADL L+ PA+ANT++ +A G D VT+V +P Sbjct: 63 KEDDPQVINHIALA----KQADLFLLPPASANTLAHLAHGFADNIVTSVALALPLEVPKF 118 Query: 134 IAPAMHESMYKHPIVRENIEKLKKLG 159 APAM+ MY++PI + NI LKK G Sbjct: 119 FAPAMNTKMYENPITQSNITLLKKFG 144 >gi|9634784 ORF FPV114 HAL3 domain [Fowlpox virus] >gi|7271612|gb|AAF44458.1|AF198100_105 (AF198100) ORF FPV114 HAL3 domain [Fowlpox virus] Length = 183 Score = 80.4 bits (195), Expect = 3e-14 Identities = 58/185 (31%), Positives = 100/185 (53%), Gaps = 25/185 (13%) Query: 20 KIVLAIPGSIAAVECVKLARELIR-HGAEVHAVMSPSATKIIHPYAMEFATGNPVITE-- 76 KI++ I GS+AAV+ L +EL R E+ V + ++ K + + G P+ T+ Sbjct: 5 KILIGITGSVAAVKLPDLIKELTRLENIELRIVATENSMK----FTDQKTIGIPIYTDKD 60 Query: 77 -------ITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPH 129 I + H+EL AD+ ++ P TANT++KIA GI D +T++V + Sbjct: 61 EWTTWKKIPDPVLHIEL----RRWADVFIIAPLTANTLAKIANGICDNLLTSIVRAWDTN 116 Query: 130 IPIMIAPAMHESMYKHPIVRENIEKLKKLG---VEFIGPRI---EEGKAKVATIDEIVYR 183 P++ PAM+ M++HPI ++I+ LK +G +E I ++ + G +A + EI YR Sbjct: 117 KPLIFCPAMNTLMWEHPITEKHIDTLKYMGFIEIECIEKKLACGDVGNGAMAEVAEI-YR 175 Query: 184 VIKKL 188 V++ + Sbjct: 176 VVRDI 180 >pir||T37719 thymidylate synthase-like DNA metabolism protein - fission yeast (Schizosaccharomyces pombe) >gi|5725409|emb|CAB52423.1| (AL109770) thymidylate synthase-like DNA metabolism protein [Schizosaccharomyces pombe] Length = 625 Score = 70.6 bits (170), Expect = 3e-11 Identities = 65/212 (30%), Positives = 106/212 (49%), Gaps = 30/212 (14%) Query: 12 KSRKLVGKK--IVLAIPGSIAAVECVKLARELIRH-GAEVHAVMSPSATKIIHPYAMEFA 68 K R+L K I++A GS+AA++ + + L+ + G +V V++ A + + A Sbjct: 22 KERQLTDSKYHILVAATGSVAAIKLTLIVKSLLTYKGVDVQVVLTDPARNFVEKEDLT-A 80 Query: 69 TGNPVITE---------ITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPV 119 G V + I H+EL A L+L+ P +ANT++K+A G+ D + Sbjct: 81 LGVNVYNNADDWKNWDGLECPITHIEL----RRWAHLLLIAPLSANTMAKMANGLCDNLL 136 Query: 120 TTVVTTAFPHIPIMIAPAMHESMYKHPIVRENIEKLKKL--GVEFIGPRIEE-------G 170 T+++ P PI++APAM+ M+ +PI +E++ + ++ EFI P IE+ G Sbjct: 137 TSLIRAWAPLKPILLAPAMNTLMWTNPITQEHLSAISRIYKNSEFIMP-IEKVLACGDIG 195 Query: 171 KAKVATIDEIVYRVIKKLHPKTLEGKRVLITA 202 +A IV RV KL LE K VL A Sbjct: 196 MGGMAEWRNIVGRVADKLQ---LEQKSVLPNA 224 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.316 0.134 0.361 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 132070022 Number of Sequences: 2977 Number of extensions: 5215924 Number of successful extensions: 19023 Number of sequences better than 1.0e-10: 35 Number of HSP's better than 0.0 without gapping: 13 Number of HSP's successfully gapped in prelim test: 22 Number of HSP's that attempted gapping in prelim test: 18875 Number of HSP's gapped (non-prelim): 36 length of query: 401 length of database: 189,106,746 effective HSP length: 62 effective length of query: 339 effective length of database: 152,000,552 effective search space: 51528187128 effective search space used: 51528187128 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.6 bits) S2: 166 (69.1 bits)