BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1897 (dfp) DE:DNA/pantothenate metabolism flavoprotein (dfp)
         (401 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||E75114 dna/pantothenate metabolism flavoprotein (dfp) PAB18...   777  0.0
pir||G71018 pantothenate metabolism flavoprotein dfp homolog PH1...   719  0.0
gi|11499235 pantothenate metabolism flavoprotein (dfp) [Archaeog...   328  9e-89
pir||D69029 pantothenate metabolism flavoprotein dfp homolog MTH...   321  1e-86
sp|Q58323|DFP_METJA DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOM...   269  3e-71
gb|AAK40553.1| DNA/pantothenate metabolism flavoprotein (dfp) [S...   269  4e-71
gb|AAG19087.1| (AE005007) pantothenate metabolism flavoprotein; ...   266  4e-70
pir||B70371 pantothenate metabolism flavoprotein dfp - Aquifex a...   237  2e-61
sp|O51752|DFP_BORBU DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOM...   226  4e-58
pir||A72498 probable DNA/pantothenate metabolism flavoprotein AP...   224  1e-57
pir||A82351 DNA/pantothenate metabolism flavoprotein VC0215 [imp...   217  2e-55
pir||A72223 pantothenate metabolism flavoprotein dfp homolog TM1...   211  1e-53
pir||D81819 hypothetical protein NMA1916 [imported] - Neisseria ...   208  7e-53
pir||A81058 DNA/pantothenate metabolism flavoprotein NMB1658 [im...   208  9e-53
dbj|BAB06229.1| (AP001515) flavoprotein [Bacillus halodurans]         205  1e-51
gb|AAF04763.1| (AF104227) pantothenate metabolism flavoprotein h...   201  1e-50
pir||B82982 DNA/pantothenate metabolism flavoprotein PA5320 [imp...   198  7e-50
pir||D69878 pantothenate metabolism flavoprotein dfp homolog ylo...   196  3e-49
emb|CAC12018.1| (AL445065) DNA/pantothenate metabolism flavoprot...   193  3e-48
sp|P44953|DFP_HAEIN DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOM...   190  2e-47
gb|AAD21550.1| (AF088896) pantothenate metabolism flavoprotein [...   184  2e-45
emb|CAB93357.1| (AL357523) putative flavoprotein homologue (part...   184  2e-45
sp|P71661|DFP_MYCTU DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOM...   173  4e-42
sp|P24285|DFP_ECOLI DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN >gi...   173  4e-42
gb|AAA61992.1| (L10328) dfp (CG Site No. 18430) [Escherichia coli]    172  5e-42
pir||H82842 DNA/pantothenate metabolism flavoprotein XF0149 [imp...   171  9e-42
pir||H75501 DNA/pantothenate metabolism flavoprotein - Deinococc...   167  2e-40
sp|P73881|DFP_SYNY3 DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOM...   166  5e-40
gb|AAB97414.1| (AF042096) panthotenate metabolism flavoprotein [...   143  4e-33
pir||E71889 pantothenate metabolism flavoprotein dfp homolog HP0...   134  2e-30
pir||A64625 pantothenate metabolism flavoprotein dfp homolog HP0...   133  3e-30
pir||F81354 DNA /pantothenate metabolism flavoprotein Cj0822 [im...   125  1e-27
sp|Q54433|DFP_STRMU DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOM...    94  3e-18
gi|9634784 ORF FPV114 HAL3 domain [Fowlpox virus] >gi|7271612|gb...    80  3e-14
pir||T37719 thymidylate synthase-like DNA metabolism protein - f...    71  3e-11

>pir||E75114 dna/pantothenate metabolism flavoprotein (dfp) PAB1897 - Pyrococcus
           abyssi (strain Orsay) >gi|5458141|emb|CAB49630.1|
           (AJ248285) DNA/pantothenate metabolism flavoprotein
           (dfp) [Pyrococcus abyssi]
           Length = 401
           
 Score =  777 bits (1985), Expect = 0.0
 Identities = 401/401 (100%), Positives = 401/401 (100%)

Query: 1   MLSHIKLIYATKSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKII 60
           MLSHIKLIYATKSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKII
Sbjct: 1   MLSHIKLIYATKSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKII 60

Query: 61  HPYAMEFATGNPVITEITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVT 120
           HPYAMEFATGNPVITEITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVT
Sbjct: 61  HPYAMEFATGNPVITEITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVT 120

Query: 121 TVVTTAFPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVATIDEI 180
           TVVTTAFPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVATIDEI
Sbjct: 121 TVVTTAFPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVATIDEI 180

Query: 181 VYRVIKKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTL 240
           VYRVIKKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTL
Sbjct: 181 VYRVIKKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTL 240

Query: 241 IRTRGSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKS 300
           IRTRGSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKS
Sbjct: 241 IRTRGSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKS 300

Query: 301 DKSITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGNTL 360
           DKSITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGNTL
Sbjct: 301 DKSITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGNTL 360

Query: 361 EAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEIEKKI 401
           EAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEIEKKI
Sbjct: 361 EAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEIEKKI 401


>pir||G71018 pantothenate metabolism flavoprotein dfp homolog PH1444 -
           Pyrococcus horikoshii >gi|3257868|dbj|BAA30551.1|
           (AP000006) 401aa long hypothetical protein DFP
           [Pyrococcus horikoshii]
           Length = 401
           
 Score =  719 bits (1835), Expect = 0.0
 Identities = 361/401 (90%), Positives = 389/401 (96%)

Query: 1   MLSHIKLIYATKSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKII 60
           ML+H+K IYA KSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVM+PSATKII
Sbjct: 1   MLNHVKRIYAKKSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMTPSATKII 60

Query: 61  HPYAMEFATGNPVITEITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVT 120
           HPYAMEFATGNPVITEITG IEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVT
Sbjct: 61  HPYAMEFATGNPVITEITGFIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVT 120

Query: 121 TVVTTAFPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVATIDEI 180
           TVVTTAFPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVA+IDEI
Sbjct: 121 TVVTTAFPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVASIDEI 180

Query: 181 VYRVIKKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTL 240
           VYRVI+KLHPKTL+GKRVL+TAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTL
Sbjct: 181 VYRVIRKLHPKTLKGKRVLVTAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTL 240

Query: 241 IRTRGSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKS 300
           I+T+GSV SFVENQI+VETVEEML AIE+ELT+KKYDVVIMAAAVSDFKPKIKA++KIKS
Sbjct: 241 IKTKGSVNSFVENQIQVETVEEMLAAIEKELTEKKYDVVIMAAAVSDFKPKIKAEDKIKS 300

Query: 301 DKSITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGNTL 360
           +KSIT+ELVPNPKII +IKE+Q DVFLVGFKAET+MEKLI EAKKQIE A SD+VIGNTL
Sbjct: 301 NKSITIELVPNPKIIDRIKELQPDVFLVGFKAETTMEKLIQEAKKQIERAKSDIVIGNTL 360

Query: 361 EAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEIEKKI 401
           EAFGS+ESKV+I+G++F KELP+M KRELAERIWDEIEK++
Sbjct: 361 EAFGSDESKVIIIGRNFEKELPKMNKRELAERIWDEIEKRL 401


>gi|11499235 pantothenate metabolism flavoprotein (dfp) [Archaeoglobus fulgidus]
           >gi|7449270|pir||D69455 pantothenate metabolism
           flavoprotein dfp homolog AF1645 - Archaeoglobus fulgidus
           >gi|2648905|gb|AAB89597.1| (AE000989) pantothenate
           metabolism flavoprotein (dfp) [Archaeoglobus fulgidus]
           Length = 404
           
 Score =  328 bits (831), Expect = 9e-89
 Identities = 197/403 (48%), Positives = 280/403 (68%), Gaps = 18/403 (4%)

Query: 1   MLS-HIKLIYATKSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKI 59
           MLS H++ I   +SRKL  KKIVL + GSIAAVE VKLAREL+R GA+V AVMS +A KI
Sbjct: 1   MLSVHLERIRGRRSRKLERKKIVLGVTGSIAAVETVKLARELVRRGADVTAVMSRAARKI 60

Query: 60  IHPYAMEFATGNPVITEITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPV 119
           IHPYA+EFATG  V+TEITGSIEHV L GE+ + ADL L+ P TANTISKIA GIDDTPV
Sbjct: 61  IHPYALEFATGKRVVTEITGSIEHVNLLGEYGD-ADLFLIAPCTANTISKIAQGIDDTPV 119

Query: 120 TTVVTTAFPH-IPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVATID 178
           TT  TTA     PI+I PAMHE+M ++  V ENI++L  +G+EF+ PRIEEGKAK  + +
Sbjct: 120 TTFATTALGSGKPIIIVPAMHEAMMRNKAVLENIQRLIDMGIEFVQPRIEEGKAKFPSTE 179

Query: 179 EIVYRVIKKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEV 238
            I   V ++L+PK ++GKRV++T+G T E IDPIRFI+N SSG+MG+ +A E   RGA+V
Sbjct: 180 TICLHVERELYPKEMKGKRVVVTSGPTYEQIDPIRFISNKSSGRMGLEIALEFWRRGADV 239

Query: 239 TLIRTRGSVKSFVE-NQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEK 297
             + ++ S  S     +I V +VE+M+ A+  E+  K  D+ + +AA +DF    +AK K
Sbjct: 240 VHVTSKPSGMSLPNYKEIRVWSVEDMMKAVLYEI-GKGCDLFVSSAAAADFIVDAEAK-K 297

Query: 298 IKSDKSITLELVPNPKIIRKIKEIQSDVFLVGFKAETSM--EKLISEAKKQIESAGSDLV 355
           IK+   + L+L  +PKII+++++I S   ++GFKAET M  ++L+  A +++     ++V
Sbjct: 298 IKTAPELVLKLKESPKIIKEVRKIYSG-HIIGFKAETGMSDDELLKVASEKMADDNLNMV 356

Query: 356 IGNTL--EAFGSEESKVVIV---GKDFVKELPRMKKRELAERI 393
           + N +     G+E+++V+I+    +++V+ L    K+ +AERI
Sbjct: 357 VANDVLERGMGTEDTRVLILTPKRQEWVEGL----KQHVAERI 395


>pir||D69029 pantothenate metabolism flavoprotein dfp homolog MTH1216 -
           Methanobacterium thermoautotrophicum (strain Delta H)
           >gi|2622326|gb|AAB85705.1| (AE000889) pantothenate
           metabolism flavoprotein [Methanobacterium
           thermoautotrophicum]
           Length = 386
           
 Score =  321 bits (813), Expect = 1e-86
 Identities = 187/390 (47%), Positives = 257/390 (64%), Gaps = 21/390 (5%)

Query: 20  KIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITEITG 79
           +I+L + GS+AA+E VKLAREL R GAEV   MS  A +IIHPYAMEFATG+  + E+TG
Sbjct: 2   EIILCVTGSVAAIEAVKLARELGRQGAEVKCFMSEDACRIIHPYAMEFATGSKPVLELTG 61

Query: 80  SIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPH-IPIMIAPAM 138
            IEHV+ AG     ADLILV PATAN I K+A  + D P+++++ TA     PI++ P+M
Sbjct: 62  EIEHVKYAG-----ADLILVAPATANIIGKLAYRLADNPISSLLLTASGMGTPIVMVPSM 116

Query: 139 HESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVATIDEIVYRVIKKLHPKTLEGKRV 198
           HE+MY      ENI +LK+ GV FI PR++EGKAK   ID IV   +++   + L+GKRV
Sbjct: 117 HEAMYA--AAAENIMRLKEEGVIFIEPRMDEGKAKFPDIDTIVLEAMRQTSSQRLQGKRV 174

Query: 199 LITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIRTRGSVKSFVENQI--- 255
           L++ G T E IDP+R ITN SSGKMG+A+A  A   GA+VT++   G+V   +  Q+   
Sbjct: 175 LVSLGGTYEPIDPVRGITNRSSGKMGLAIARRAYIEGADVTVV--AGTVSVEIPPQLRSF 232

Query: 256 EVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSDKSITLELVPNPKII 315
             ET EEM   + E +    +DV I AAAV+DFKP +  + KI S +  ++EL PNPK+I
Sbjct: 233 RAETAEEMAERVRELVA--DHDVFISAAAVADFKP-VYTERKISSSEEFSVELRPNPKVI 289

Query: 316 RKIKEIQSDVFLVGFKAETSM--EKLISEAKKQIESAGSDLVIGN--TLEAFGSEESKVV 371
              +EI  + F+VGFKAE  +  E L+  A+KQI  +G D+V+ N  ++E FGS+ ++ +
Sbjct: 290 GIAREINPEAFIVGFKAEYDVDNEALVESARKQIRESGVDMVVANDVSVEGFGSDRNRAI 349

Query: 372 IVGKDFVKELPRMKKRELAERIWDEIEKKI 401
           IV  D V ELP M+K ELA  I DE+ +K+
Sbjct: 350 IV-SDMVTELPLMEKEELASIIIDEVIRKV 378


>sp|Q58323|DFP_METJA DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOMOLOG
           >gi|2129175|pir||A64414 pantothenate metabolism
           flavoprotein MJ0913 - Methanococcus jannaschii
           >gi|1591587|gb|AAB98918.1| (U67535) pantothenate
           metabolism flavoprotein (dfp) [Methanococcus jannaschii]
           Length = 403
           
 Score =  269 bits (681), Expect = 3e-71
 Identities = 169/403 (41%), Positives = 250/403 (61%), Gaps = 18/403 (4%)

Query: 6   KLIYATKSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAM 65
           KL+  TKS+ L  KKI++A+  SIAA+E  KL RELIRHGAEV+ +++    KII   A+
Sbjct: 10  KLLKGTKSKLLENKKILVAVTSSIAAIETPKLMRELIRHGAEVYCIITEETKKIIGKEAL 69

Query: 66  EFATGNPVITEITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTT 125
           +F  GN V  EITG IEH+ L     N+ D +L+ PATAN ISKI  GI D  V T    
Sbjct: 70  KFGCGNEVYEEITGDIEHILL----YNECDCLLIYPATANIISKINLGIADNIVNTTALM 125

Query: 126 AFPHIPIMIAPAMHESMYKHPIVRENIEKLK-KLGVEFIGPRIEEGKAKVATIDEIVYRV 184
            F + PI I PAMHE+M+    ++ +I+KLK K  +  I P+ EEGKAKVA I+++V  V
Sbjct: 126 FFGNKPIFIVPAMHENMFN--AIKRHIDKLKEKDKIYIISPKFEEGKAKVANIEDVVKAV 183

Query: 185 IKKL-HPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIRT 243
           I+K+ +    EG RVLI  G T E+ID +R I+N SSGKMGVALAE     G  V +I  
Sbjct: 184 IEKIGNNLKKEGNRVLILNGGTVEFIDKVRVISNLSSGKMGVALAEAFCKEGFYVEVITA 243

Query: 244 RGSVKSFVENQIEVETVEEMLG-AIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSDK 302
            G    +     +V T +EML  AIE     K +D++I +AA+SDF  +   + K+ S++
Sbjct: 244 MGLEPPYYIKNHKVLTAKEMLNKAIE---LAKDFDIIISSAAISDFTVE-SFEGKLSSEE 299

Query: 303 SITLELVPNPKIIRKIKEIQSDVFLVGFKAETSME--KLISEAKKQIESAGSDLVIGNTL 360
            + L+L  NPK++ +++ I  D  ++GFKAE +++  +LI+ AK+++     +++I N L
Sbjct: 300 ELILKLKRNPKVLEELRRIYKDKVIIGFKAEYNLDEKELINRAKERLNKYNLNMIIANDL 359

Query: 361 EA--FGSEESKVVIVGKDFVKELPRMKKRELAERIWDEIEKKI 401
               FG +  +V I+ K  V+++   KK E++ERI ++++K +
Sbjct: 360 SKHYFGDDYIEVYIITKYEVEKISGSKK-EISERIVEKVKKLV 401


>gb|AAK40553.1| DNA/pantothenate metabolism flavoprotein (dfp) [Sulfolobus
           solfataricus]
           Length = 413
           
 Score =  269 bits (680), Expect = 4e-71
 Identities = 163/408 (39%), Positives = 254/408 (61%), Gaps = 18/408 (4%)

Query: 6   KLIYATKSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAM 65
           K I  + S +L  KKI+LA+ GS+A  + + LAR L+R+GAEV  ++S  A K+I P   
Sbjct: 10  KKIIGSISNELADKKILLAVTGSVAIYKSLDLARSLMRNGAEVSVIISKDAAKLISPEMF 69

Query: 66  EFATGNPVITEITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVT-TVVT 124
           ++ATGN V+T++TG +EHV LA ++    D+++V P+TANT+ KIA GI DTP+T T + 
Sbjct: 70  KWATGNNVVTKLTGDLEHVSLAEDN----DVMIVAPSTANTMVKIAYGIADTPITATALN 125

Query: 125 TAFPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVATIDEIVYRV 184
                 P++I P+MH  MY  P V +  ++LK++GVE I P I    A    ++ +  R+
Sbjct: 126 FVGMKKPLIIVPSMHLQMYISPQVADAADRLKRIGVEVIEPEIVGDLAHYPKLEYLTSRI 185

Query: 185 IK-KLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLI-- 241
               L  K L G  +L TAG TREY+D +RFI+N SSG MG+++A EA FRGA+V +I  
Sbjct: 186 TSYVLRGKDLSGFNILATAGPTREYLDSVRFISNPSSGTMGISIANEAYFRGAKVRVICG 245

Query: 242 RTRGSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSD 301
                ++ +V++ + VET EEML  + + +   K++VVI+A A +D+K K K+  KI S 
Sbjct: 246 PISSKIEPYVKDIVYVETTEEMLNEVVKSIENGKFNVVILAGAPADYKFKNKSDTKIDSH 305

Query: 302 KSI-TLELVPNPKIIRKIKEIQSDVFLVGFKAET--SMEKLISEAKKQIESAGSDLVIGN 358
             I  +EL   PKI   I++   +V LVGF AET  S E+LI +AK ++   G DL++ N
Sbjct: 306 TEIPKVELERTPKISEYIRKY--NVLLVGFSAETVNSDEELIEKAKIKMRRHGFDLIVAN 363

Query: 359 TLE----AFGSEESKVVIVGKD-FVKELPRMKKRELAERIWDEIEKKI 401
            +      F SE ++V+++ K+  V+++P+  K  +A +I D +++++
Sbjct: 364 NVRRKDIGFSSEYNEVIVIDKNGDVRKIPKNFKTVIARKILDIVKEQL 411


>gb|AAG19087.1| (AE005007) pantothenate metabolism flavoprotein; Dfp [Halobacterium
           sp. NRC-1]
           Length = 392
           
 Score =  266 bits (672), Expect = 4e-70
 Identities = 156/392 (39%), Positives = 233/392 (58%), Gaps = 19/392 (4%)

Query: 16  LVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVIT 75
           L G  + + + GSIAAV+ V+   EL R GA V AVM+ SA  IIHP+A+EFAT NPV+T
Sbjct: 2   LSGVNVAVGVTGSIAAVKVVEFVHELRRRGACVRAVMTESAQGIIHPWAVEFATENPVVT 61

Query: 76  EITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAF-PHIPIMI 134
           EITG++ HVEL G  +  AD+ +V PATANT+ KIA  +DD+PVTT VTTA    +P+++
Sbjct: 62  EITGTVPHVELCGR-DGWADVFVVAPATANTVGKIAAAVDDSPVTTCVTTAVGADVPVVV 120

Query: 135 APAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVATIDEIVYRVIKKLHPKTLE 194
            PAMHE MY HP VR+ I+++   GV  + PRIEEGKAK+     IV+   +    + L 
Sbjct: 121 VPAMHEPMYDHPGVRDAIDRVSSWGVSVVDPRIEEGKAKLPRESTIVHETARAAGEQPLA 180

Query: 195 GKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIR--TRGSVKSFVE 252
           G  V++T+GAT E IDP+R +TN +SG+ G A+A     RGA VTL+   + G    + +
Sbjct: 181 GTHVVVTSGATSEAIDPVRVLTNRASGRTGRAVAAACYVRGARVTLVHDASDGGAVPYAD 240

Query: 253 NQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSDK-SITLELVPN 311
            + +V +  EM  A          D ++ AAA+SD+  +  A EK++S +  + L L P 
Sbjct: 241 VR-DVSSAAEMTAATLTACADA--DALVSAAAISDYTVE-AADEKLRSGREDVALSLEPT 296

Query: 312 PKIIRKIKEIQSDVFLVGFKAETSM-------EKLISEAKKQIESAGSDLVIGNTLEAFG 364
            K++  +++   D+ +VGFKAET         + +++ A+  ++  G   V+ N     G
Sbjct: 297 RKLVGAVRDDNPDLPIVGFKAETPADDGTAGDDSMVAAARSLLQRDGLAFVVANDAGVMG 356

Query: 365 SEESKVVIVGKDFVKELPRMKK---RELAERI 393
           ++E++ + V  D V E    K+     +AER+
Sbjct: 357 NDETRALFVTADSVSEYAGHKRGLGARIAERL 388


>pir||B70371 pantothenate metabolism flavoprotein dfp - Aquifex aeolicus
           >gi|2983357|gb|AAC06944.1| (AE000708) pantothenate
           metabolism flavoprotein [Aquifex aeolicus]
           Length = 388
           
 Score =  237 bits (598), Expect = 2e-61
 Identities = 148/383 (38%), Positives = 221/383 (57%), Gaps = 20/383 (5%)

Query: 21  IVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITEITGS 80
           I++ + G IA+ +  +L REL R G  V  +++P A K + P   +  +GN   T+    
Sbjct: 3   ILIGVCGGIASYKVCELVRELKRKGHSVKTILTPFAEKFMSPLTFQTLSGNKAYTDKDWE 62

Query: 81  IE---HVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIPIMIAPA 137
            E   H+ LA      AD+ L+ PATANTI+KIA GI D  +TT +       P+++APA
Sbjct: 63  EEPLAHINLA----RWADVFLIAPATANTIAKIANGISDNLLTTTILAYGK--PLLVAPA 116

Query: 138 MHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEIVYRVIKKLHPK 191
           M+  MYK P  +EN++KLK+ G   I P        E G+ K+A+ID ++  +      K
Sbjct: 117 MNTVMYKSPSTQENLKKLKEWGHVIIEPEFGVLACKEVGEGKLASIDRLIDWIYYVSEEK 176

Query: 192 TLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIRTRGSVKSFV 251
            L+GK+VLIT GAT+E+IDP+RFI+N SSG+MG +LA    ++GAEV +I    + K   
Sbjct: 177 PLKGKKVLITCGATKEFIDPVRFISNYSSGEMGFSLARIFRWKGAEVKVIAGTTTAKEPP 236

Query: 252 ENQ-IEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSDKSITLELVP 310
           E + I V+T EEM   + E       D+V+M AAV+DFKP   +KEKIK    I LELV 
Sbjct: 237 EVEIIRVQTTEEMREKVLEHYDWA--DIVVMNAAVADFKPSKVSKEKIKKRDKILLELVK 294

Query: 311 NPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGNTLEAFGSEESKV 370
           NP I+ ++   +    LVGF  E+  + L+  A++++E    DL++ N ++  G +E + 
Sbjct: 295 NPDILEELGRKKGYKILVGFALES--DNLLEYAREKLERKNLDLIVANPVKVMGKKEHEG 352

Query: 371 VIVGKDFVKELPRMKKRELAERI 393
            ++ KD + ELP+  K E A  I
Sbjct: 353 YLITKDQIVELPKGSKLENARFI 375


>sp|O51752|DFP_BORBU DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOMOLOG
           >gi|7449264|pir||C70201 pantothenate metabolism
           flavoprotein dfp homolog BB0812 - Lyme disease
           spirochete >gi|2688739|gb|AAC67145.1| (AE001179)
           pantothenate metabolism flavoprotein (dfp) [Borrelia
           burgdorferi]
           Length = 390
           
 Score =  226 bits (570), Expect = 4e-58
 Identities = 150/391 (38%), Positives = 232/391 (58%), Gaps = 26/391 (6%)

Query: 19  KKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITEIT 78
           K I++ I G IA+ + V +   L++ G +V  +M+ +ATK I P  +E  + N +IT + 
Sbjct: 5   KHILIGICGGIASYKSVYIVSSLVKLGYKVKVIMTQNATKFITPLTLETISKNKIITNLW 64

Query: 79  ----GSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIPIMI 134
                 +EH+++A      A LILV PAT NTISKIA GI D  +TT+++ +    P   
Sbjct: 65  DLDHNEVEHIKIA----KWAHLILVIPATYNTISKIASGIADDALTTIISASTA--PTYF 118

Query: 135 APAMHESMYKHPIVRENIEKLKKLGVEFIGPR------IEEGKAKVATIDEIVYRVIKKL 188
           A AM+  MY +PI++ENI+KLK    +FI P             ++   D+I+  ++ + 
Sbjct: 119 AIAMNNIMYSNPILKENIKKLKTYNYKFIEPDKGFLACSSNALGRLKNEDKIIKIILNEF 178

Query: 189 HPKT-LEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIRTRGSV 247
           + K  L+ K++LITA  T E IDPIR+ +N S+GKMG  LA+EA   GA+VT+I T  + 
Sbjct: 179 NQKDYLKNKKILITASRTEELIDPIRYFSNTSTGKMGFCLAQEAVKLGAQVTII-TGPTN 237

Query: 248 KSFVE--NQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSDK--S 303
           ++  E  N I+++T  EM    E      K++++I AAAV+DFKPK     KIK +K   
Sbjct: 238 ENDPEGVNIIKIKTAMEMYK--EALKIYNKFEIIIGAAAVADFKPKHIFNSKIKKNKINR 295

Query: 304 ITLELVPNPKIIRKIKEIQ-SDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGNTLEA 362
           + ++LV NP II+ I   +  +  ++GF AE S + LI +AK++++    D +I N L+ 
Sbjct: 296 LYIKLVKNPDIIQHIGHNKLKNQIVIGFCAENS-KNLIQKAKEKLKKKNLDFIIANELKY 354

Query: 363 FGSEESKVVIVGKDFVKELPRMKKRELAERI 393
           FGS+ +KV I+ K  +KELP M+K E+A+ I
Sbjct: 355 FGSKLNKVYIINKQSIKELPEMEKSEVAKEI 385


>pir||A72498 probable DNA/pantothenate metabolism flavoprotein APE1959 -
           Aeropyrum pernix (strain K1) >gi|5105657|dbj|BAA80969.1|
           (AP000063) 437aa long hypothetical DNA/pantothenate
           metabolism flavoprotein [Aeropyrum pernix]
           Length = 437
           
 Score =  224 bits (565), Expect = 1e-57
 Identities = 145/393 (36%), Positives = 219/393 (54%), Gaps = 17/393 (4%)

Query: 18  GKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITEI 77
           GK IVL +  S+A    + LAR L+R GA V  VM+P A K++ P    +A+G PV T  
Sbjct: 47  GKTIVLGVTASVALYRSLDLARWLLRRGARVITVMTPEAAKLVSPEMFHWASGGPVYTGF 106

Query: 78  TGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPH-IPIMIAP 136
           TG +EH+ +A      A  ++V PAT +T++KIA G+ D PV     +   +  P++  P
Sbjct: 107 TGGVEHISIA----RAASAMVVAPATLSTLAKIAHGVVDNPVALAAVSIMGYGKPVIAVP 162

Query: 137 AMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVATIDEI--VYRVIKKLHPKTLE 194
           AMH +MY+ P  RE +++L+  GV  + P+IE G AK      +  +     +   + LE
Sbjct: 163 AMHGNMYESPQAREVVDRLRSQGVLVVDPKIEGGVAKYPDTHAVGRITAAQARKGLRDLE 222

Query: 195 GKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIRTRGSVK-SFVEN 253
           G R L+T G+TRE+ID +RFI+N SSG MG+  A E   RGAEV ++    SV+   + N
Sbjct: 223 GIRALVTLGSTREWIDRVRFISNPSSGVMGLEAALELYARGAEVDVVAGYTSVEIPHLFN 282

Query: 254 QIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSDKSITLELVPNPK 313
            ++ ET E+M  A+EE  +K++YD V+ AAA  DF+P    + KI+S + + LEL P PK
Sbjct: 283 TVKTETTEDMAAAVEELTSKREYDAVVAAAAPVDFRPAGAFEGKIRSGQRLVLELEPTPK 342

Query: 314 IIRKIKEIQSDVFLVGFKAE--TSMEKLISEAKKQIESAGSDLVIGNTL----EAFGSEE 367
           ++  I   +    LV F AE   +++ L   A +++E   +DLV+ N +      F S  
Sbjct: 343 VLEGI--ARRPKVLVAFAAEYVDNLDSLRDPALEKMEKYDADLVVANRVGVEGVGFASPL 400

Query: 368 SKVVIVGKDFVKELPRMKKREL-AERIWDEIEK 399
             V+++ K     L     +E+ A  I DEI K
Sbjct: 401 LDVLMLDKSGEAVLKGSFHKEIVAAVIADEIAK 433


>pir||A82351 DNA/pantothenate metabolism flavoprotein VC0215 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9654622|gb|AAF93391.1| (AE004111) DNA/pantothenate
           metabolism flavoprotein [Vibrio cholerae]
           Length = 399
           
 Score =  217 bits (546), Expect = 2e-55
 Identities = 143/408 (35%), Positives = 230/408 (56%), Gaps = 30/408 (7%)

Query: 14  RKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPV 73
           + L GKKI+L I G IAA +C +L R L+  GA V  VM+ +A + I P  M+  +G PV
Sbjct: 2   QSLAGKKILLGISGGIAAYKCAELTRRLVERGATVQVVMTHAAKEFITPLTMQAVSGRPV 61

Query: 74  ITEIT-----GSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFP 128
              +       S+ H+ELA      ADL+L+ PATA+ I+++A G+ +  +TT++     
Sbjct: 62  SDSLLDPAAEASMGHIELA----KWADLVLLAPATADLIARMAAGMGNDLLTTLILAT-- 115

Query: 129 HIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEE------GKAKVATIDEIVY 182
             P+ IAPAM++ MY++   +EN++ L + G    GP   E      G  ++    E+V 
Sbjct: 116 SAPVAIAPAMNQQMYRNIATQENLQTLIRRGYLTWGPAAGEQACGDVGPGRMLEPMELVA 175

Query: 183 RVIKKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIR 242
                  PK L GKRVLITAG TRE +DP+R+ITN SSGKMG ALA+ A   GA+VTL+ 
Sbjct: 176 HCENFFAPKILVGKRVLITAGPTREALDPVRYITNHSSGKMGFALAKAAAQLGADVTLVS 235

Query: 243 TRGSVKSFV-ENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSD 301
               + + V  N+I+V++  EM  A+ +E T   + + I  AAV+D++P+  A++KIK  
Sbjct: 236 GPVHLPTPVGVNRIDVQSGLEMHSAVMKEAT--SHQIFIACAAVADYRPQTVAEQKIKKS 293

Query: 302 K---SITLELVPNPKIIRKIKEI-QSDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIG 357
           +   ++T+E+V NP I+  +  + ++  F VGF AET  + + + A+ ++     D++  
Sbjct: 294 RDNDTLTIEMVKNPDIVASVAALTENRPFTVGFAAET--QDVETYARSKLVRKNLDMICA 351

Query: 358 NTL----EAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEIEKKI 401
           N +    + F S ++ + +  K+    LP   K  LA  +   I +++
Sbjct: 352 NDVSIAGQGFNSNDNALTLFWKEGQHSLPLTSKDALASAVMHLIHEQM 399


>pir||A72223 pantothenate metabolism flavoprotein dfp homolog TM1687 -
           Thermotoga maritima (strain MSB8)
           >gi|4982263|gb|AAD36754.1|AE001809_6 (AE001809)
           DNA/pantothenate metabolism flavoprotein [Thermotoga
           maritima]
           Length = 394
           
 Score =  211 bits (532), Expect = 1e-53
 Identities = 153/396 (38%), Positives = 222/396 (55%), Gaps = 30/396 (7%)

Query: 20  KIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITEI-- 77
           +IVL +   IA  + V LA +L + G E+H VM+P AT++I P     A GN  +     
Sbjct: 2   RIVLGVSSGIAIYKAVDLASKLRKEGHELHVVMTPDATRMISPVVFS-AVGNCSVYHDWM 60

Query: 78  ---TGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIPIMI 134
               G I H E++      AD+++V PATANTISKIA GI D  + T+V  AF     ++
Sbjct: 61  DVRNGWIPHTEIS----RTADVLVVAPATANTISKIANGIADN-LLTLVALAFDKDAKIL 115

Query: 135 APAMHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEIVYRVIKKL 188
            P M+  MY + + +EN+EKLK  G   + P        E GK +    ++IV  V    
Sbjct: 116 VPTMNYRMYSNKLFQENLEKLKNNGWFVVEPEEGHLACGEVGKGRYPENEKIVEAVHLLT 175

Query: 189 HPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIRTRGSVK 248
            PK L GK+VLITAG TRE ID +RFITNASSGKMG ALA  A+  GA V+L+    S+K
Sbjct: 176 FPKKLAGKKVLITAGPTRERIDAVRFITNASSGKMGYALATVAKRMGARVSLVSGPTSLK 235

Query: 249 S--FVENQIEVETVEEMLGAIEEELTKK--KYDVVIMAAAVSDFKPKIKAKEKI-KSDKS 303
              +V+  ++VE+ EEM     EE+ K+    D+VIM AAV D++PK   + K+ K++  
Sbjct: 236 PPYYVDEFVKVESAEEMY----EEVMKRFEDTDIVIMNAAVGDYRPKKVFEGKLKKTEND 291

Query: 304 ITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSD-LVIGNTLEA 362
           + L L     I++++ + +S+  LVGF AE  +E     A K++     D LV+ +  +A
Sbjct: 292 LVLHLERTKDILKELGQRKSNQILVGFAAE--VENFEENAVKKLREKNLDLLVLNDARKA 349

Query: 363 FGSEESKVVIVGKD-FVKELPRMKKRELAERIWDEI 397
           F S+  +V I G+D F+K +    K  +A  I D +
Sbjct: 350 FSSDRVEVYIYGRDGFIKRIDEDDKIRVACGILDVV 385


>pir||D81819 hypothetical protein NMA1916 [imported] - Neisseria meningitidis
           (group A strain Z2491) >gi|7380550|emb|CAB85137.1|
           (AL162757) hypothetical protein [Neisseria meningitidis
           Z2491]
           Length = 394
           
 Score =  208 bits (525), Expect = 7e-53
 Identities = 140/398 (35%), Positives = 218/398 (54%), Gaps = 27/398 (6%)

Query: 17  VGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITE 76
           +GK I+L + GSIAA +  +L R L + G  V  VMS SAT+ + P   +  +GNPV+T+
Sbjct: 1   MGKHILLGVTGSIAAYKSCELVRLLKKQGHSVTVVMSRSATEFVSPLTFQALSGNPVLTD 60

Query: 77  ITGS-----IEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIP 131
             GS     +EH+ L       AD+ L+ PA+ NT++KI  G+ D  +T +   A    P
Sbjct: 61  THGSNGSNGMEHINLT----RNADVFLIAPASMNTVAKICNGVADNLLTNLA--AARKCP 114

Query: 132 IMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEIVYRVI 185
           + IAPAM+  M+ +P  + NI +L   G+    P +      E G  ++    E++  + 
Sbjct: 115 LAIAPAMNVEMWLNPANQRNIAQLVSDGITVYMPGLGEQACGENGMGRMPEPAELLDLLP 174

Query: 186 KKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLI--RT 243
               PK L GK++LITAGAT E IDP+R ITN SSGKMGVALA      GAEV+LI  + 
Sbjct: 175 DLWTPKILRGKKILITAGATFEAIDPVRGITNTSSGKMGVALARACRAAGAEVSLIHGQL 234

Query: 244 RGSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSDKS 303
           +  +   + + ++  + E+M  A+   +  +K D  I  AAVSD+K K ++ +K K DK+
Sbjct: 235 QTELPFGISDTVQAVSAEDMHRAVHRLI--EKQDAFISVAAVSDYKVKNRSTQKFKKDKN 292

Query: 304 ---ITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAK-KQIESAGSDLVIGNT 359
              +++EL  NP I+  I  + +  F +GF AET  E +++ A+ K+I+     +V  + 
Sbjct: 293 AKPLSIELDENPDILASIASLPNPPFCIGFAAET--ENVMAYAREKRIKKKIPVIVANDV 350

Query: 360 LEAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEI 397
             A G   +++ I+G D     P   K E A +I + +
Sbjct: 351 SIAMGKPTNRITIIGDDGELSFPETSKDEAAMQIVERL 388


>pir||A81058 DNA/pantothenate metabolism flavoprotein NMB1658 [imported] -
           Neisseria meningitidis (group B strain MD58)
           >gi|7226910|gb|AAF42007.1| (AE002516) DNA/pantothenate
           metabolism flavoprotein [Neisseria meningitidis MC58]
           Length = 394
           
 Score =  208 bits (524), Expect = 9e-53
 Identities = 138/398 (34%), Positives = 219/398 (54%), Gaps = 27/398 (6%)

Query: 17  VGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITE 76
           +GK I+L + GSIAA +  +L R L + G  V  VMS SAT+ + P   +  +GNPV+T+
Sbjct: 1   MGKHILLGVTGSIAAYKSCELVRLLKKQGHSVTVVMSRSATEFVSPLTFQALSGNPVLTD 60

Query: 77  ITGS-----IEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIP 131
             G      +EH+ L       AD+ L+ PA+ NT++KI  G+ D  +T++   A    P
Sbjct: 61  THGGNGSNGMEHINLT----RNADVFLIAPASMNTVAKICNGVADNLLTSLA--AARKCP 114

Query: 132 IMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEIVYRVI 185
           + IAPAM+  M+ +P  + NI +L   G+    P +      E G  ++    E++  + 
Sbjct: 115 LAIAPAMNVEMWLNPANQRNIAQLVSDGITVYMPGLGEQACGENGMGRMPEPAELLDLLP 174

Query: 186 KKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLI--RT 243
               PK L+GK+VLITAGAT E IDP+R ITN SSGKMGVALA      GAEV+LI  + 
Sbjct: 175 DLWTPKILKGKKVLITAGATFEAIDPVRGITNISSGKMGVALARACRAAGAEVSLIHGQL 234

Query: 244 RGSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSDKS 303
           + ++   + + ++  + E M  A+   + K+  D  I  AAVSD++ K ++ +K K DK+
Sbjct: 235 QTALPFGISDTVQAVSAENMHRAVHRLIDKQ--DAFISVAAVSDYRVKNRSTQKFKKDKN 292

Query: 304 ---ITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGNTL 360
              +++EL  NP I+  I  + +  F +GF AET  E +++ A+++       +++ N +
Sbjct: 293 AKPLSIELDENPDILASIASLPNPPFCIGFAAET--ENVMTYAREKRIKKKLPMIVANDV 350

Query: 361 E-AFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEI 397
             A G   +++ I+G D     P   K E A RI + +
Sbjct: 351 SIAMGKPTNRITIIGDDGELSFPETSKDEAAMRIVERL 388


>dbj|BAB06229.1| (AP001515) flavoprotein [Bacillus halodurans]
           Length = 404
           
 Score =  205 bits (515), Expect = 1e-51
 Identities = 136/398 (34%), Positives = 225/398 (56%), Gaps = 30/398 (7%)

Query: 16  LVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVIT 75
           L GK++VL + G IAA +    A +L++ GAEV  VM+  A K + P   +  T +PV  
Sbjct: 2   LQGKRVVLGVSGGIAAFKSAAFASKLVQAGAEVKVVMTEGAKKFVTPLTFQALTRHPVYD 61

Query: 76  EI-----TGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHI 130
           +         I H++LA    + AD+I++ PATAN I K+A G+ D  ++T++       
Sbjct: 62  DTFSEPDPSEIAHIQLA----DWADVIIIAPATANLIGKLANGVADDMLSTMLLAT--KA 115

Query: 131 PIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEE------GKAKVATIDEIVYRV 184
           PI +APAM+ +MY+HP V+ N+++L K G   + P          GK ++   ++++  +
Sbjct: 116 PIYLAPAMNVNMYEHPAVQRNMQQLAKDGYRLLEPGAGYLACGWIGKGRMPEPEDLLKTI 175

Query: 185 IKKLHP--KTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIR 242
                P   +L GK+++ITAG T+E IDPIRF TN SSGKMG AL + A   G  VTLI 
Sbjct: 176 EVHFTPPSSSLAGKKIVITAGPTQETIDPIRFFTNRSSGKMGYALTKAARDFGGNVTLIS 235

Query: 243 TRGSV-KSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKI-KS 300
              S+ K    + + V++ ++M  A+  E +    DVVI  AAV+D++P++  ++K+ K 
Sbjct: 236 GPTSLEKPDGVSVVNVKSAQDMYEAVLAEFSDA--DVVIKTAAVADYRPRVVHEQKVKKK 293

Query: 301 DKSITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGNTL 360
           D    +EL     I++ + E +   FLVGF AE+  +++ + A+K+++   +D+++ N +
Sbjct: 294 DGDWVIELERTVDILKTLGEKKESQFLVGFAAES--QEVETYAQKKLKEKNADMIVANNV 351

Query: 361 ----EAFGSEESKVVIVGKD-FVKELPRMKKRELAERI 393
                 F ++ ++V +  K   VK LP M K E+A R+
Sbjct: 352 TEEGAGFQTDTNRVTVYFKQGDVKPLPLMTKDEVAHRL 389


>gb|AAF04763.1| (AF104227) pantothenate metabolism flavoprotein homolog [Listeria
           monocytogenes]
           Length = 399
           
 Score =  201 bits (506), Expect = 1e-50
 Identities = 146/403 (36%), Positives = 220/403 (54%), Gaps = 37/403 (9%)

Query: 18  GKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITEI 77
           GK I+LA+ G IA  + V L  +L + GA V  +M+  A + + P + +  + N V T+ 
Sbjct: 3   GKNILLAVSGGIAVYKAVALTSKLTQAGANVKVMMTAHAQEFVPPLSFQVLSKNDVYTDT 62

Query: 78  -----TGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIPI 132
                +  + H++LA    + ADL++V PATAN I K+A GI D  VTT +       P+
Sbjct: 63  FDEKKSSVVAHIDLA----DWADLVIVAPATANVIGKMANGIADDMVTTTILAT--EAPV 116

Query: 133 MIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEG--------KAKVATIDEIVYRV 184
            +APAM+  M +HP V  NI +L   GV FI P  EEG        + ++   ++IV R+
Sbjct: 117 WVAPAMNVHMIQHPAVIRNINRLYADGVRFIEP--EEGYLACGYVGRGRLEEPEKIVLRI 174

Query: 185 IKKLHP--KTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIR 242
            +        L+GK VL+TAGATRE +D IR+ TN S+GKMG ++AE A   GA VTLI 
Sbjct: 175 AEFFQEDKNLLQGKNVLVTAGATREKLDLIRYFTNHSTGKMGFSIAESAARHGANVTLIT 234

Query: 243 TRGS--VKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKS 300
           T  +  V   VE  I VE+ EEM  A+ E   K   D+ +M AAV+D+ P   + +KIK 
Sbjct: 235 TSKALPVPHGVE-AIYVESAEEMHQAVNER--KVSQDIFVMTAAVADYTPAQVSDQKIKK 291

Query: 301 DK-SITLELVPNPKIIRKIKEIQ-SDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGN 358
                T+ +     I+ +I + + S+  ++GF AET  E + + A+K++ S  +D+++ N
Sbjct: 292 QPGDFTIAMKRTKDILLEIGQHKTSEQVVIGFAAET--ENVEANARKKLTSKNADMIVAN 349

Query: 359 TLE----AFGSEESKVVIVGKDFVKE-LPRMKKRELAERIWDE 396
            +      F  + + V    KD   E LP + K+E+AE I  E
Sbjct: 350 NISEAGAGFSGDTNIVTFYRKDGSSEALPILDKKEVAEHIIKE 392


>pir||B82982 DNA/pantothenate metabolism flavoprotein PA5320 [imported] -
           Pseudomonas aeruginosa (strain PAO1)
           >gi|9951637|gb|AAG08705.1|AE004944_9 (AE004944)
           DNA/pantothenate metabolism flavoprotein [Pseudomonas
           aeruginosa]
           Length = 402
           
 Score =  198 bits (499), Expect = 7e-50
 Identities = 129/385 (33%), Positives = 213/385 (54%), Gaps = 35/385 (9%)

Query: 14  RKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPV 73
           ++L  K+IVL + G IAA +  +L R L   GAEV  VM+    + I P  ++  +G+PV
Sbjct: 2   QRLYRKRIVLGVGGGIAAYKSAELVRRLRDQGAEVRVVMTQGGREFITPLTLQALSGHPV 61

Query: 74  ITEIT-----GSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFP 128
            T++       ++ H+ELA      ADL+L+ PATA+ ++++  G+ +  +TT+V     
Sbjct: 62  HTDLLDPAAEAAMGHIELA----RWADLVLIAPATADLMARLVQGVANDLLTTLVLAT-- 115

Query: 129 HIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEIVY 182
              I +APAM+++M++    + N E L++ G    GP        + G  ++   +E+  
Sbjct: 116 DAQIALAPAMNQAMWRDTATQANAELLRQRGFHLFGPAAGSQACGDVGLGRMLEAEELAQ 175

Query: 183 RVIKKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIR 242
           R       + L G  VLITAG T+E IDP+R+ITN SSGKMG ALAE A   GA VTL+ 
Sbjct: 176 RAADCFQRQALTGVHVLITAGPTQENIDPVRYITNHSSGKMGFALAEAAVEAGARVTLV- 234

Query: 243 TRGSVKSFVEN---QIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIK 299
             G V     +   +++V +  +ML A E  +     D++I +AAV+D++P++ A  K+K
Sbjct: 235 -TGPVHLPTPDRVQRVDVVSARDMLAACEAAM---PCDLLIASAAVADYRPEVVAAHKLK 290

Query: 300 SD----KSITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLV 355
            D    + + L+LV NP I+  + + +   F VGF AET  E L+  A ++++    DL+
Sbjct: 291 KDPTSGEGLLLQLVRNPDILATLAQREDRPFSVGFAAET--ENLLDYAARKLKDKNLDLI 348

Query: 356 IGNTLE----AFGSEESKVVIVGKD 376
           + N +      F S+E+ + ++ +D
Sbjct: 349 VANDVANPSIGFNSDENAITVIDRD 373


>pir||D69878 pantothenate metabolism flavoprotein dfp homolog yloI - Bacillus
           subtilis >gi|2337799|emb|CAA74260.1| (Y13937) putative
           Dfp protein [Bacillus subtilis]
           >gi|2633942|emb|CAB13443.1| (Z99112) similar to
           pantothenate metabolism flavoprotein [Bacillus subtilis]
           Length = 406
           
 Score =  196 bits (494), Expect = 3e-49
 Identities = 147/408 (36%), Positives = 213/408 (52%), Gaps = 40/408 (9%)

Query: 16  LVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVIT 75
           L  + ++L + G IA  +   L  +L++ GA V  +M+ SA + + P   +  + + V T
Sbjct: 2   LNNRNVLLCVSGGIAVYKACALTSKLVQAGANVKVIMTESACRFVSPLTFQALSRHEVYT 61

Query: 76  EI-----TGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHI 130
           +         I H++ A    + ADLI+V PATAN I K+A GI D  +TT +  A    
Sbjct: 62  DTFKEQNPSVISHIDAA----DWADLIIVAPATANVIGKLANGIADDMLTTTLLAATA-- 115

Query: 131 PIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEE------GKAKVATIDEIVYRV 184
           P+ IAPAM+  MY HP V+ NI  L + G  FI P          GK ++   + IV   
Sbjct: 116 PVWIAPAMNVHMYDHPAVKRNISVLYQDGYCFIEPSEGYLACGYVGKGRLEEPENIVKLA 175

Query: 185 IKKLHPKT---LEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLI 241
            K    +T   LEGK V+ITAG TRE IDP+RF TN S+GKMG ALAE A   GA V LI
Sbjct: 176 EKHFAEETSAPLEGKHVVITAGPTREAIDPVRFFTNKSTGKMGYALAEAAVQLGARVILI 235

Query: 242 RTRGS------VKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAK 295
               S      +  F+  Q   +  E +L   +        D+VI  AAV+DF PK    
Sbjct: 236 SGPVSLDQPKGLAEFIPVQSAADMREAVLSVYDAS------DIVIKTAAVADFTPKTVFD 289

Query: 296 EKI-KSDKSITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDL 354
            K+ K D  +TLEL     I++++ E + +  LVGF AET  + +   A+K++ +   DL
Sbjct: 290 HKMKKQDGGMTLELKRTVDILKELGEKKKEQILVGFAAET--QDIEHYARKKLAAKNLDL 347

Query: 355 VIGNTLEA----FGSEESKVVIVGKD-FVKELPRMKKRELAERIWDEI 397
           ++ N ++A    FG++ + V I  KD   +ELP M K +++  I  EI
Sbjct: 348 IVANDVKANGAGFGADTNIVTIFFKDGHKRELPIMSKLDVSFEILQEI 395


>emb|CAC12018.1| (AL445065) DNA/pantothenate metabolism flavoprotein related protein
           [Thermoplasma acidophilum]
           Length = 394
           
 Score =  193 bits (485), Expect = 3e-48
 Identities = 121/310 (39%), Positives = 183/310 (59%), Gaps = 7/310 (2%)

Query: 13  SRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNP 72
           SR L G  +++A  GSI+      L R+L R GA+V   MS S+  ++ P  M +A+   
Sbjct: 10  SRMLEGYTVIVATSGSISIYRIPDLVRDLRREGADVIVGMSQSSAAMVSPEVMRWASERD 69

Query: 73  VITEITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPH-IP 131
           V+TEITG IEH+ L  E+  K  ++L+ PA+ NT+ K+A GI D+  +   + AF H + 
Sbjct: 70  VVTEITGRIEHISLFTENREK-KILLIAPASYNTLGKMANGITDSVPSLFFSFAFGHGVK 128

Query: 132 IMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRIEEGKAKVATIDEIVYRVIKKLHPK 191
            ++APAMH SM ++PI   NIEKL+ LGV F+ P  ++ KAK+     I+  V + +H K
Sbjct: 129 TVVAPAMHRSMMENPINLANIEKLRSLGVNFVDPIYDDEKAKLNGNGAILDGVCRSVH-K 187

Query: 192 TLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAE--VTLIRTRGSVKS 249
            L GK++LI +G   E IDP+R ITNA SG  GV LA  A   GA     L  T+  +  
Sbjct: 188 DLAGKKILIISGRGEEPIDPVRSITNAGSGFTGVWLARNAYRMGASSITYLGNTQFDLPG 247

Query: 250 FVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSDKSITLELV 309
           +V+  +E  T+++      +E+ ++ YD VI+ AA+ DFK   ++++K  SD+ + + L 
Sbjct: 248 YVK-YVEAHTIDDFEKKTMDEI-EEGYDAVIVNAALPDFKVAERSQKKYSSDQPLRITLN 305

Query: 310 PNPKIIRKIK 319
           P  KII KI+
Sbjct: 306 PREKIIYKIR 315


>sp|P44953|DFP_HAEIN DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOMOLOG
           >gi|1075104|pir||G64104 pantothenate metabolism
           flavoprotein dfp homolog HI0953 - Haemophilus influenzae
           (strain Rd KW20) >gi|1573978|gb|AAC22614.1| (U32776)
           DNA/pantothenate metabolism flavoprotein (dfp)
           [Haemophilus influenzae Rd]
           Length = 400
           
 Score =  190 bits (479), Expect = 2e-47
 Identities = 139/403 (34%), Positives = 223/403 (54%), Gaps = 32/403 (7%)

Query: 15  KLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVI 74
           KL GK IV+ I G IAA + ++L R L +  AEV  V++P+A + + P  ++  +GN V 
Sbjct: 2   KLNGKHIVVGITGGIAAYKTIELIRLLRKAEAEVRVVLTPAAAEFVTPLTLQAISGNAVS 61

Query: 75  TEITG-----SIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPH 129
             +       ++ H+ELA      AD I++ PA+A+ I+++  G+ +  ++T+      +
Sbjct: 62  QSLLDPQAELAMGHIELA----KWADAIIIAPASADFIARLTIGMANDLLSTICLAT--N 115

Query: 130 IPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEIVYR 183
            PI +APAM++ MY   I ++N+  L+  G+E IGP        + GK +++  +EI   
Sbjct: 116 APIFLAPAMNQQMYHQSITQQNLTTLQTRGIELIGPNSGFQACGDMGKGRMSEPEEIFTA 175

Query: 184 VIKKLHPKT-LEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIR 242
           +      K  L+G  V ITAG TRE IDP+R+I+N SSGKMG A+AE    RGA VTLI 
Sbjct: 176 LSDFFSQKQDLQGLNVSITAGPTREAIDPVRYISNHSSGKMGFAIAEAFAKRGANVTLI- 234

Query: 243 TRGSVKSFVE---NQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKI- 298
             G V        N+I V + +EM  A  E   K +  + I  AAV+D++    A++KI 
Sbjct: 235 -AGPVNLTTPKNVNRINVISAQEMWQASLESAVKNQ--IFIGCAAVADYRVTEVAEQKIK 291

Query: 299 KSDKSITLELVPNPKIIRKIKEIQSD-VFLVGFKAETSMEKLISEAKKQIESAGSDLVIG 357
           KS   I+++L+ NP II  +  +++   F VGF AET  + +   AK ++E    D++  
Sbjct: 292 KSGDEISIKLIKNPDIISDVGHLKTHRPFTVGFAAET--QNVDDYAKDKLERKNLDMICA 349

Query: 358 NTL---EAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEI 397
           N +   + F ++E+ + +  K+  K+L    K ELA  + +EI
Sbjct: 350 NDVSGGQVFNADENALQLFWKNGHKKLSLKSKVELAADLVNEI 392


>gb|AAD21550.1| (AF088896) pantothenate metabolism flavoprotein [Zymomonas mobilis]
           Length = 417
           
 Score =  184 bits (462), Expect = 2e-45
 Identities = 131/409 (32%), Positives = 214/409 (52%), Gaps = 40/409 (9%)

Query: 16  LVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVIT 75
           L GK+I+L I GSIAA++   + R   +  A++  +++      I P A+   +GNPV  
Sbjct: 5   LNGKRILLVISGSIAAIKAPDIIRLFRKKKADIRCLITKGGANFITPLALASLSGNPVAQ 64

Query: 76  EI-----TGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHI 130
           ++       SI H+ LA E    AD+I+V PA+A+ ISK+A G+ +   +TVV  A    
Sbjct: 65  DMWDESEEASIRHIRLARE----ADMIIVAPASADFISKMAHGLANDLASTVVLAA--DS 118

Query: 131 PIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEIVYRV 184
           PI++APAM+  M+ H   + NI +LK  G+ F+ P        E G  ++A  ++I+   
Sbjct: 119 PILVAPAMNHRMWHHSATQRNIHQLKSDGISFVDPEAGAMACGETGIGRLAAPEDILLSA 178

Query: 185 ----IKKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTL 240
                ++ + + L+ +  ++TAG T E IDP+R++ N SSGK G A+AE  +  GA+VTL
Sbjct: 179 ESLFAEEQNHQFLKNRHFIVTAGPTHEPIDPVRYLANRSSGKQGFAIAEALQKLGAKVTL 238

Query: 241 IRTRGSVKSFVENQIE---VETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEK 297
           +   G V     +++E   VET  EM  A+E  L     D  I  AAV+D++      + 
Sbjct: 239 V--TGPVYQNTPDRVERVNVETAIEMEKAVENALPA---DGAIFTAAVADWRFNYSPSKY 293

Query: 298 IKSDKSITLELVPNPKIIRKI--KEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLV 355
            K      L  +  P+I+  I  ++I     +VGF AE+  E L+  AK +++  G D +
Sbjct: 294 KKGRSEPELIPIEKPEILSNISKRKIDRPSLVVGFAAES--ENLLENAKVKLQQKGCDWI 351

Query: 356 IGNTL-------EAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEI 397
           I N +        A G + +K+ I     ++  P + K+E+A R+  +I
Sbjct: 352 IANPVIESEDAPSAMGGDYNKIFIASHAGIENWPLLSKKEVASRLASKI 400


>emb|CAB93357.1| (AL357523) putative flavoprotein homologue (partial) [Streptomyces
           coelicolor A3(2)]
           Length = 376
           
 Score =  184 bits (462), Expect = 2e-45
 Identities = 126/370 (34%), Positives = 198/370 (53%), Gaps = 29/370 (7%)

Query: 5   IKLIYATKSRKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYA 64
           ++  Y ++   +   K+VL + G IAA +  +L R L   G EV  V + SA   +    
Sbjct: 17  VRARYPSRGETVDKPKVVLGVSGGIAAYKACELLRRLTESGHEVRVVPTASALHFVGAAT 76

Query: 65  MEFATGNPVITEITGSIE---HVELAGEHENKADLILVCPATANTISKIACGIDDTPVTT 121
               +GNPV TE+   +    HV + G+H   ADL++V PATA+ ++K A G+ D  +T 
Sbjct: 77  WSALSGNPVSTEVWDDVHEVPHVRI-GQH---ADLVVVAPATADMLAKAAHGLADDLLTN 132

Query: 122 VVTTAFPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKV- 174
            + TA    P++ APAMH  M++HP  +EN+  L++ G   I P +      + GK ++ 
Sbjct: 133 TLLTA--RCPVVFAPAMHTEMWEHPATQENVAALRRRGAVVIEPAVGRLTGVDTGKGRLP 190

Query: 175 --ATIDEIVYRVIKK-LHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEA 231
               I E+  RV+ + +    L G+ V+++AG TRE +DP+RF+ N SSGK G ALA  A
Sbjct: 191 DPGEIFEVCRRVLARGVREPDLAGRHVVVSAGGTREPLDPVRFLGNRSSGKQGYALARTA 250

Query: 232 EFRGAEVTLIRTRGSVKSFV-ENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKP 290
             RGA VTL+    S+      + + V T  E+  A+         D V+MAAAV+DF+P
Sbjct: 251 AARGARVTLVAANASMPDPAGVDVVPVGTAVELREAVLRAAADA--DAVVMAAAVADFRP 308

Query: 291 KIKAKEKIK---SDKSITLELVPNPKIIRKIKE--IQSDVFLVGFKAETSMEKLISEAKK 345
              A  KIK     +   + LV NP I+ +I +   +S   +VGF AET  + +++  + 
Sbjct: 309 ATYATGKIKKKDDQEPAPITLVRNPDILAEISQTRARSGQVVVGFAAET--DDVLANGRV 366

Query: 346 QIESAGSDLV 355
           +++  G DL+
Sbjct: 367 KLKRKGCDLL 376


>sp|P71661|DFP_MYCTU DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOMOLOG
           >gi|7449274|pir||E70899 pantothenate metabolism
           flavoprotein dfp - Mycobacterium tuberculosis (strain
           H37RV) >gi|1542899|emb|CAB02174.1| (Z80108) dfp
           [Mycobacterium tuberculosis]
           Length = 418
           
 Score =  173 bits (433), Expect = 4e-42
 Identities = 127/413 (30%), Positives = 213/413 (50%), Gaps = 38/413 (9%)

Query: 15  KLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVI 74
           K + K++++ + G IAA +   + R+L      V  + + SA + +     E  +G PV 
Sbjct: 5   KRIPKQVIVGVSGGIAAYKACTVVRQLTEASHRVRVIPTESALRFVGAATFEALSGEPVC 64

Query: 75  TEITG---SIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIP 131
           T++     ++ HV L      +ADL++V PATA+ +++ A G  D  +T  + TA    P
Sbjct: 65  TDVFADVPAVPHVHLG----QQADLVVVAPATADLLARAAAGRADDLLTATLLTA--RCP 118

Query: 132 IMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEI--VYR 183
           ++ APAMH  M+ HP   +N+  L++ G   + P        + G  ++   +EI  + +
Sbjct: 119 VLFAPAMHTEMWLHPATVDNVATLRRRGAVVLEPATGRLTGADSGAGRLPEAEEITTLAQ 178

Query: 184 VIKKLH---PKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTL 240
           ++ + H   P  L G+++L+TAG TRE IDP+RFI N SSGK G A+A  A  RGA+VTL
Sbjct: 179 LLLERHDALPYDLAGRKLLVTAGGTREPIDPVRFIGNRSSGKQGYAVARVAAQRGADVTL 238

Query: 241 I--RTRGSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKI 298
           I   T G V       + V + +++  A+ +       DV++MAAAV+DF+P   A  KI
Sbjct: 239 IAGHTAGLVDPAGVEVVHVSSAQQLADAVSKHAPTA--DVLVMAAAVADFRPAQVATAKI 296

Query: 299 KS--DKSITLELVPNPKII------RKIKEIQSDVFLVGFKAET--SMEKLISEAKKQIE 348
           K   +   T+EL+ N  ++      R   ++ +   +VGF AET  +   ++  A+ ++ 
Sbjct: 297 KKGVEGPPTIELLRNDDVLAGVVRARAHGQLPNMRAIVGFAAETGDANGDVLFHARAKLR 356

Query: 349 SAGSDLVIGNTL---EAFGSEESKVVIVGKDFVKE-LPRMKKRELAERIWDEI 397
             G DL++ N +    AF  + +   ++  D  +  L    K  +A RI D I
Sbjct: 357 RKGCDLLVVNAVGEGRAFEVDSNDGWLLASDGTESALQHGSKTLMASRIVDAI 409


>sp|P24285|DFP_ECOLI DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN >gi|7430385|pir||A65165
           pantothenate metabolism flavoprotein dfp - Escherichia
           coli  (strain K-12) >gi|1790070|gb|AAC76663.1|
           (AE000441) flavoprotein affecting synthesis of DNA and
           pantothenate metabolism [Escherichia coli K12]
           Length = 430
           
 Score =  173 bits (433), Expect = 4e-42
 Identities = 127/405 (31%), Positives = 216/405 (52%), Gaps = 34/405 (8%)

Query: 16  LVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVIT 75
           L GKKIVL + G IAA +  +L R L   GA+V   M+ +A   I P +++  +G PV  
Sbjct: 27  LAGKKIVLGVSGGIAAYKTPELVRRLRDRGADVRVAMTEAAKAFITPLSLQAVSGYPVSD 86

Query: 76  EIT-----GSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHI 130
            +       ++ H+EL       ADL+++ PATA+ I+++A G+ +  V+T+        
Sbjct: 87  SLLDPAAEAAMGHIELG----KWADLVILAPATADLIARVAAGMANDLVSTICLAT--PA 140

Query: 131 PIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEIVYRV 184
           P+ + PAM++ MY+    + N+E L   G+   GP        + G  ++     IV   
Sbjct: 141 PVAVLPAMNQQMYRAAATQHNLEVLASRGLLIWGPDSGSQACGDIGPGRMLDPLTIVDMA 200

Query: 185 IKKLHP-KTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIRT 243
           +    P   L+   ++ITAG TRE +DP+R+I+N SSGKMG A+A  A  RGA VTL+  
Sbjct: 201 VAHFSPVNDLKHLNIMITAGPTREPLDPVRYISNHSSGKMGFAIAAAAARRGANVTLVSG 260

Query: 244 RGSVKS--FVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSD 301
             S+ +  FV+ +++V T  EM  A+   +  ++ ++ I  AAV+D++    A EKIK  
Sbjct: 261 PVSLPTPPFVK-RVDVMTALEMEAAVNASV--QQQNIFIGCAAVADYRAATVAPEKIKKQ 317

Query: 302 KS----ITLELVPNPKIIRKIKEIQSD-VFLVGFKAETSMEKLISEAKKQIESAGSDLVI 356
            +    +T+++V NP I+  +  ++    ++VGF AET+  +  +  K+  ++   DL+ 
Sbjct: 318 ATQGDELTIKMVKNPDIVAGVAALKDHRPYVVGFAAETNNVEEYARQKRIRKNL--DLIC 375

Query: 357 GNTL----EAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEI 397
            N +    + F S+ + + +  +D  K LP  +K  L + + DEI
Sbjct: 376 ANDVSQPTQGFNSDNNALHLFWQDGDKVLPLERKELLGQLLLDEI 420


>gb|AAA61992.1| (L10328) dfp (CG Site No. 18430) [Escherichia coli]
           Length = 430
           
 Score =  172 bits (432), Expect = 5e-42
 Identities = 127/405 (31%), Positives = 215/405 (52%), Gaps = 34/405 (8%)

Query: 16  LVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVIT 75
           L GKKIVL + G IAA +  +L R L   GA+V   M+ +A   I P +++  +G PV  
Sbjct: 27  LAGKKIVLGVSGGIAAYKTPELVRRLRDRGADVRVAMTEAAKAFITPLSLQAVSGYPVSD 86

Query: 76  EIT-----GSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHI 130
            +       ++ H+EL       ADL+++ PATA+ I+++A G+ +  V+T+        
Sbjct: 87  SLLDPAAEAAMGHIELG----KWADLVILAPATADLIARVAAGMANDLVSTICLAT--PA 140

Query: 131 PIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEIVYRV 184
           P+ + PAM++ MY+    + N+E L   G+   GP        + G  +      IV   
Sbjct: 141 PVAVLPAMNQQMYRAAATQHNLEVLASRGLLIWGPDSGSQACGDIGPGRXXDPLTIVDMA 200

Query: 185 IKKLHP-KTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIRT 243
           +    P   L+   ++ITAG TRE +DP+R+I+N SSGKMG A+A  A  RGA VTL+  
Sbjct: 201 VAHFSPVNDLKHLNIMITAGPTREPLDPVRYISNHSSGKMGFAIAAAAARRGANVTLVSG 260

Query: 244 RGSVKS--FVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSD 301
             S+ +  FV+ +++V T  EM  A+   +  ++ ++ I  AAV+D++    A EKIK  
Sbjct: 261 PVSLPTPPFVK-RVDVMTALEMEAAVNASV--QQQNIFIGCAAVADYRAATVAPEKIKKQ 317

Query: 302 KS----ITLELVPNPKIIRKIKEIQSD-VFLVGFKAETSMEKLISEAKKQIESAGSDLVI 356
            +    +T+++V NP I+  +  ++    ++VGF AET+  +  +  K+  ++   DL+ 
Sbjct: 318 ATQGDELTIKMVKNPDIVAGVAALKDHRPYVVGFAAETNNVEEYARQKRIRKNL--DLIC 375

Query: 357 GNTL----EAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEI 397
            N +    + F S+ + + +  +D  K LP  +K  L + + DEI
Sbjct: 376 ANDVSQPTQGFNSDNNALHLFWQDGDKVLPLERKELLGQLLLDEI 420


>pir||H82842 DNA/pantothenate metabolism flavoprotein XF0149 [imported] -
           Xylella fastidiosa (strain 9a5c)
           >gi|9104938|gb|AAF82962.1|AE003868_8 (AE003868)
           DNA/pantothenate metabolism flavoprotein [Xylella
           fastidiosa]
           Length = 409
           
 Score =  171 bits (430), Expect = 9e-42
 Identities = 133/407 (32%), Positives = 221/407 (53%), Gaps = 42/407 (10%)

Query: 14  RKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPV 73
           R L G++++L + G IAA + ++L R L   G +V   M+ SA + + P + +  +G   
Sbjct: 8   RSLNGQRLLLCVSGGIAAYKSLELVRRLCGAGVQVQVAMTASAQQFVTPLSFQALSGQST 67

Query: 74  ITEI-TGSIE----HVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTV--VTTA 126
            T +  G+ E    H+ELA      A+ +L+ PA+A+ I+++A G+ D  VTT+   TTA
Sbjct: 68  RTTLWDGNAEQAMGHIELA----RWAECVLIAPASADVIARLAHGLADDLVTTLCLATTA 123

Query: 127 FPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPR---IEEGKAKVATIDE---I 180
                ++I PAM+ +M+ HP  + N+  L   GV+ IGP    + EG + +  + E   I
Sbjct: 124 L----LIICPAMNHNMWLHPATQANVAMLVGRGVQVIGPEDGPLAEGVSGLGRMSEPEAI 179

Query: 181 VYRVIKKLHPKTLEG-----KRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRG 235
           V  +++ + P  + G     +R++I+AG T E +DP+R++ N SSGKMG ALA  A   G
Sbjct: 180 VAALVQGVSPAPVHGGLFHGQRIVISAGPTFEDLDPVRYLGNRSSGKMGFALASAAVSHG 239

Query: 236 AEVTLIRTRGSVKSFVE---NQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKI 292
           AEV L+   G V         +++V +  +M  A+   L+    DV I AAAV+D+ PK 
Sbjct: 240 AEVVLV--AGPVYQPTPPGVTRVDVRSAAQMRDAV---LSAFPADVYIGAAAVADYAPKS 294

Query: 293 KAKEKI-KSDKSITLELVPNPKIIRKIKEIQSDV-FLVGFKAETSMEKLISEAKKQIESA 350
              +KI KS +++TLELV    I+ ++    +++ F+VGF AET    +   A+ ++ + 
Sbjct: 295 VLPQKIKKSGQTLTLELVRTQDILSEVAAQTANLKFVVGFAAET--HDVERYARGKLAAK 352

Query: 351 GSDLVIGNTL----EAFGSEESKVVIVGKDFVKELPRMKKRELAERI 393
             DL+I N +      F S+++ V +  +   +      K ELAER+
Sbjct: 353 HLDLIIANQVGIVGNGFESDDNAVTVYWQGGERVFASCSKVELAERL 399


>pir||H75501 DNA/pantothenate metabolism flavoprotein - Deinococcus radiodurans
           (strain R1) >gi|6458275|gb|AAF10158.1|AE001916_4
           (AE001916) DNA/pantothenate metabolism flavoprotein
           [Deinococcus radiodurans]
           Length = 422
           
 Score =  167 bits (419), Expect = 2e-40
 Identities = 132/405 (32%), Positives = 209/405 (51%), Gaps = 39/405 (9%)

Query: 22  VLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITEITGSI 81
           ++ + GS+AAV+     R L   GA    + + +A   I P ++  A    V T+ T   
Sbjct: 19  LVIVGGSMAAVKAPTALRRLREGGASTAVIATRAALAFITPLSLATAGNCEVATDETWFA 78

Query: 82  -----EHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIPIMIAP 136
                +H+ LA     +A + +V  A+A  ++  A G  DT  T  + +A   +  +  P
Sbjct: 79  PQPIAQHLSLA-----RARVTVVLGASAELLAAAAHGHADTLATATLLSAEGQV--LWVP 131

Query: 137 AMHESMYKHPIVRENIEKLKKLGVEFIGPRIE--------EGKAKVATIDEIVYRVIKKL 188
           AM+E M+ HP V+ N E+L+  G  F+GP            G  ++A  + I  R +  L
Sbjct: 132 AMNERMWLHPAVQANAERLRGWGHLFLGPETGAFGTPGEGSGTGRMAEPEAIAARALALL 191

Query: 189 H---------PKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVT 239
           +         P+ L G +V+++AG TREY+DP+RFI+N SSGKMG A+AEEA  RGAEV 
Sbjct: 192 NEQDAEAEAAPQDLAGLKVVVSAGPTREYLDPVRFISNPSSGKMGFAVAEEARTRGAEVV 251

Query: 240 LIRTRGSVKSFVENQ-IEVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKI-KAKEK 297
           L+    ++      Q + +ET  EM  AI E       D+V+M AA++D++    K++++
Sbjct: 252 LVTGPVNLPDLSGVQTVRIETALEMQAAIME--AAGDADMVVMTAAIADYRAAAPKSEKE 309

Query: 298 IKSDKSITLELVPNPKIIRKIKEIQS---DVFLVGFKAETSMEKLISEAKKQIESAGSDL 354
            K+   +T+ L PNP I+  +   Q+      LVGF  ET      +  K Q ++A   L
Sbjct: 310 AKTPGDVTIHLTPNPDILAGLGAEQAAHPGRVLVGFAMETHAGVERAALKAQRKNADFIL 369

Query: 355 VIGNTLE--AFGSEESKVVIVGKDFV-KELPRMKKRELAERIWDE 396
           +   T E  AFG ++++V +V  D    + PR+ KRE+A R+ DE
Sbjct: 370 LNYPTREGTAFGGDDNQVTLVRADGTHADWPRISKREVARRLLDE 414


>sp|P73881|DFP_SYNY3 DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOMOLOG
           >gi|7449262|pir||S75082 pantothenate metabolism
           flavoprotein dfp homolog sll0250 - Synechocystis sp.
           (strain PCC 6803) >gi|1653027|dbj|BAA17944.1| (D90910)
           pantothenate metabolism flavoprotein [Synechocystis sp.]
           Length = 402
           
 Score =  166 bits (415), Expect = 5e-40
 Identities = 124/407 (30%), Positives = 212/407 (51%), Gaps = 31/407 (7%)

Query: 18  GKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVI--T 75
           GK+I++ + G IAA +  ++  +L + GAEV  +++  A K + P        +P     
Sbjct: 4   GKRILIGVGGGIAAYKICEVVSQLFQQGAEVRVILTAEAEKFVTPLTFTTLARHPAYGDA 63

Query: 76  EITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIPIMIA 135
           +    I H  L  +    AD+ L+ P TA+T++K+  G  D  ++  V  +    PI++A
Sbjct: 64  DFWQPIHHRPLHIDLGEWADIFLIAPLTAHTLAKLGHGFADDLLSNTVLAS--SCPILLA 121

Query: 136 PAMHESMYKHPIVRENIEKLKKLG---VEFIGPR------IEEGKAKVATIDEIVYRVIK 186
           PAM+  M++   V+ N+++L  LG      + P          G  ++A   +I++R+  
Sbjct: 122 PAMNTDMWEQEAVQRNLQQL--LGDRRYHLLAPNGGLLACDRRGVGRLAEPAQIMHRLQA 179

Query: 187 KLHP---KTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIRT 243
            L     + L GKR+LITAG T+EY+D +RFI N S+GKMG+ALA+ A  RGA VTLI  
Sbjct: 180 LLFTGGQEDLRGKRILITAGGTQEYLDAVRFIGNPSTGKMGLALAQSAGDRGARVTLIHG 239

Query: 244 RGSVKSFVENQIEVETV--EEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKI-KS 300
                      I +  V  E+M  A+ ++      D ++MAAAV+D KP      KI K 
Sbjct: 240 PIGDLPIPMGVISMAVVNAEQMEQALAQQAPLA--DWIVMAAAVADVKPAQTWTGKIAKQ 297

Query: 301 DKSITLELVPNPKIIRKI-KEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGNT 359
           D   +L L P P +I ++ K+ +    LVGF A+     +++ AK++++    D+++ N 
Sbjct: 298 DLPDSLPLAPVPDLIAQVSKQKRPHQLLVGFAAQAG--DIVTPAKEKLQRKNLDVIVANP 355

Query: 360 LE----AFGSEESKVVIVGKDFVK-ELPRMKKRELAERIWDEIEKKI 401
           ++     FG++ ++ VI+ +   +  +    K  +A RIW  + ++I
Sbjct: 356 IDQPQSGFGTDSNQAVIIDRHGSQTAIAPCSKLAMAHRIWQYLLERI 402


>gb|AAB97414.1| (AF042096) panthotenate metabolism flavoprotein [Bradyrhizobium
           japonicum]
           Length = 444
           
 Score =  143 bits (356), Expect = 4e-33
 Identities = 125/420 (29%), Positives = 199/420 (46%), Gaps = 44/420 (10%)

Query: 16  LVGKKIVLAIPGSIAAVECVKLARELIR--HGAEVHAVM---SPSATKII--HPYAMEFA 68
           L    + L I G IA ++ + L R L    H   +       S S T ++   P+ M  +
Sbjct: 26  LAEASVTLIIGGGIARLKSLDLIRRLKERCHRGPLRTDQTRPSSSVTPLVGQRPFRMSAS 85

Query: 69  TGNPVITEITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFP 128
                I        H+ LA +     DLI+V PATA+ +SK+A G  D   + ++     
Sbjct: 86  IPTCPIPRSEFDAGHIRLARD----CDLIVVAPATADLMSKMANGHADDLASAILLAT-- 139

Query: 129 HIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPR----IEEGKAKVATIDEIVY-- 182
           +  +++APAM+  M+ +   R N+ +L++ GV  IGP      E G+A +  + E +   
Sbjct: 140 NRKVLLAPAMNPLMWNNAATRRNVAQLQRDGVVLIGPNSGEMAEAGEAGIGRMSEALEIA 199

Query: 183 ----RVIKKLHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEV 238
               R+++   P+ L GKRVLITAG T E IDP+R+I N SSGK G A+A  A+  GAEV
Sbjct: 200 AAAERLLRPPVPRPLAGKRVLITAGPTHEPIDPVRYIANRSSGKQGFAIAAAAQAAGAEV 259

Query: 239 TLIRTRGSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIMAAAVS-DFKPKIKAKEK 297
            L+   G V       + V+ VE     +E+       D+ I     S D++   + ++K
Sbjct: 260 ILV--SGPVDLGDPQGVTVKHVESARQMLEQVQAALPADIAIFQPPRSPDWRVANEGEQK 317

Query: 298 IKSDKS--ITLELVPNPKIIRKIKEI--QSDVFLVGFKAETSMEKLISEAKKQIESAGSD 353
           +K   +    L+LV NP I+  I ++  +    L+GF AET  E LI  AK ++   G D
Sbjct: 318 LKKTSAGMPPLQLVENPDILATIAKLTDKRPPLLIGFAAET--EHLIDNAKTKLARKGCD 375

Query: 354 LVIGNTLE----AFGSEESKVVIV--------GKDFVKELPRMKKRELAERIWDEIEKKI 401
            ++ N +       G + + V ++        G+  V   P M K ++A  +   I K +
Sbjct: 376 WIVANDVSPATGVMGGDRNTVHLISRKNGEKNGEIAVDSWPAMTKEQVATELIAHIVKSV 435


>pir||E71889 pantothenate metabolism flavoprotein dfp homolog HP0841 -
           Helicobacter pylori (strain J99)
           >gi|4155346|gb|AAD06359.1| (AE001508) PANTOTHENATE
           METABOLISM FLAVOPROTEIN [Helicobacter pylori J99]
           Length = 425
           
 Score =  134 bits (334), Expect = 2e-30
 Identities = 115/417 (27%), Positives = 198/417 (46%), Gaps = 39/417 (9%)

Query: 14  RKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPV 73
           R L  K+++L + GSIAA + ++L R L + GA +  VMS  A K I P + E  + + V
Sbjct: 12  RLLENKRVLLLVSGSIAAYKSLELVRLLFKSGASIQVVMSKGAQKFIKPLSFEALSHHKV 71

Query: 74  ITEITGSIEHVELAGEHEN------KADLILVCPATANTISKIACGI-DDTPVTTVVTTA 126
           + +      +      H N       ADL++  P +AN++SKIA  + D+T   T +  A
Sbjct: 72  LHDRNEKWYYNHQNKLHHNHIACAASADLLIFAPLSANSLSKIAHALADNTISATFLACA 131

Query: 127 FPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPR------IEEGKAKVATIDEI 180
            P I   +AP+M+ +M   PI++ N+++LK      +  +        +G   +A   EI
Sbjct: 132 SPKI---LAPSMNTNMLNSPIIQSNLKRLKDSNHIILDTQNALLACNTKGDGAMAEPLEI 188

Query: 181 VYRVIKK-LHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVT 239
           +++  +  L     E + V++  GA+ E ID +R I+N SSG    ALA    F+GA+VT
Sbjct: 189 LFKATQTLLKDAYFENREVIVMGGASVEKIDSVRVISNLSSGIQASALALALYFKGAKVT 248

Query: 240 LIRTR------GSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIM-AAAVSDFKPKI 292
           LI +         + S + +  +  + E  L    + L K     ++   AA+SD+ PK 
Sbjct: 249 LIASNFPTPLPKEIASVLVS--DTASYENALNEAAKNLQKHALKPLLFNLAAISDYLPKT 306

Query: 293 KAKEKIKSD---KSITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAK---KQ 346
               K+K     +++ +E V N  ++  +   Q     +GFKAE   +  I  A+   K 
Sbjct: 307 SFNHKLKKSELGETLNVECVQNKDLLASVNPNQ--FVKIGFKAEDDQQNAIKNAQNLLKP 364

Query: 347 IESAGSDLVIG-----NTLEAFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEIE 398
            +  G D  +           FGS ++++ +      +++P M K E + +I D I+
Sbjct: 365 SQDNGKDCSVAALNLIKDSRPFGSLDNELWLFSHKKTQKIPSMNKLEASFKILDFIK 421


>pir||A64625 pantothenate metabolism flavoprotein dfp homolog HP0841 -
           Helicobacter pylori (strain 26695)
           >gi|2313973|gb|AAD07888.1| (AE000595) pantothenate
           metabolism flavoprotein (dfp) [Helicobacter pylori
           26695]
           Length = 425
           
 Score =  133 bits (332), Expect = 3e-30
 Identities = 118/417 (28%), Positives = 201/417 (47%), Gaps = 39/417 (9%)

Query: 14  RKLVGKKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPV 73
           R L  K+++L + GSIAA + ++L R L + GA +  VMS  A K I P + E  + + V
Sbjct: 12  RLLENKRVLLLVSGSIAAYKSLELVRLLFKSGASIQVVMSKGAKKFIKPLSFEALSHHKV 71

Query: 74  ITEITGSIEHVELAGEHEN------KADLILVCPATANTISKIACGIDDTPVT-TVVTTA 126
           + +      +      H N       ADL++  P + N++SKIA  + D  V+ T +  A
Sbjct: 72  LHDRNEKWYYNHQNALHHNHIACAANADLLIFAPLSTNSLSKIAHALADNIVSATFLACA 131

Query: 127 FPHIPIMIAPAMHESMYKHPIVRENIEKLKKLGVEFIGPR------IEEGKAKVATIDEI 180
            P I   +AP+M+ +M   PI + N+++LK      +  +        +G   +A   EI
Sbjct: 132 SPKI---LAPSMNTNMLNSPITQSNLKRLKDSNHIILDTKNALLACDTKGDGAMAEPLEI 188

Query: 181 VYRVIKK-LHPKTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVT 239
           +++  +  L     E + V++  GA+ E ID +R I+N SSG    ALA    F+GA+VT
Sbjct: 189 LFKAAQTLLKDAYFENREVIVMGGASIEKIDSVRTISNLSSGIQASALALALYFKGAKVT 248

Query: 240 LIRTR------GSVKSFVENQIEVETVEEMLGAIEEELTKKKYDVVIM-AAAVSDFKPKI 292
           LI +         + S + +  +  + E  L +    L K     ++   AA+SD+ PK 
Sbjct: 249 LIASNFPTPLPKEITSVLVS--DTASYENALNSAANNLQKHALKPLLFNLAAISDYVPKT 306

Query: 293 KAKEKIKSD---KSITLELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAK---KQ 346
               K+K     +++ +E V N  ++  I   Q     +GFKAE + +  I  A+   K 
Sbjct: 307 SFNYKLKKSEIGETLNIECVQNKDLLVSINPNQ--FVKIGFKAEDNQQNAIKNAQNLLKP 364

Query: 347 IESAGSD--LVIGNTLE---AFGSEESKVVIVGKDFVKELPRMKKRELAERIWDEIE 398
            +  G D  +V  N ++    FGS E+++ +      +++P M K E + +I D I+
Sbjct: 365 FKDNGKDCSVVALNLIKDSRPFGSLENELWLFSHHKTQKIPSMNKLEASFKILDFIK 421


>pir||F81354 DNA /pantothenate metabolism flavoprotein Cj0822 [imported] -
           Campylobacter jejuni (strain NCTC 11168)
           >gi|6968268|emb|CAB73087.1| (AL139076) DNA /pantothenate
           metabolism flavoprotein [Campylobacter jejuni]
           Length = 384
           
 Score =  125 bits (310), Expect = 1e-27
 Identities = 115/396 (29%), Positives = 196/396 (49%), Gaps = 29/396 (7%)

Query: 19  KKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITEIT 78
           K I+LAI GSIA  +  +L     + G  V  ++S    K     + E A  + V+ E  
Sbjct: 2   KTILLAISGSIAFYKSYELISLFKKEGFRVKVLLSNGLLKFASKMSFE-ALVDEVLCEEN 60

Query: 79  GSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIPIMIAPAM 138
            S ++           DL+L  PA+ N+I+K+A GI D      +  A  + P++IAPA 
Sbjct: 61  ESWQNSNNHIAFSKDVDLVLFTPASVNSINKLAFGIADNLFIQTLIAA--NKPLIIAPAA 118

Query: 139 HESMYKHPIVRENIEKLKKLGVEFIGPRI------EEGKAKVATIDEIVYRVIKK--LHP 190
           + +M+ H   + +++ LK+     I P        +EG   +A + +I + + K+  L  
Sbjct: 119 NTNMFHHFSTQNSLKILKENKALIIEPICKVLACKDEGVGALAEVKDI-FNITKRELLKE 177

Query: 191 KTLEGKRVLITAGATREYIDPIRFITNASSGKMGVALAEEAEFRGAEVTLIRTRGSVKSF 250
           K    K V+IT G TRE ID +R ++N SSGKM  A+A+   F GA V L+    SV+  
Sbjct: 178 KFWCNKSVVITGGGTRERIDDVRCVSNFSSGKMAKAIADAFYFLGARVKLL---SSVEFD 234

Query: 251 VENQI-EVETVEEMLGAIEEELTKKKYDVVIMAAAVSDFKPKIKAKEKIKSD---KSITL 306
              ++ + E+ +++   +++ L+   +D +IM AAVSDF P+   K KIK +   + + L
Sbjct: 235 TPYELCKFESSKDLKELLDKNLS---HDFLIMTAAVSDFIPQ-SVKGKIKKNEHLQGLNL 290

Query: 307 ELVPNPKIIRKIKEIQSDVFLVGFKAETSMEKLISEAKKQIESAGSDLVIGNTLEA---F 363
            L  N  +++  K  Q     +GFK E   +  +  AKK ++    D+V  N ++    F
Sbjct: 291 HLSLNEDLLKTCK-FQGK--KIGFKMEFDSQNALENAKKSLKDKQLDMVCLNIIDQKNYF 347

Query: 364 GSEESKVVIVGKDFVKELPRMKKRELAERIWDEIEK 399
           GS+++++  +  +   +     K +LA  +    EK
Sbjct: 348 GSDQNELYFITLNNENKSTLQSKEKLAFELVKWCEK 383


>sp|Q54433|DFP_STRMU DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOMOLOG
           >gi|1216490|gb|AAC44502.1| (U48885) DNA/pantothenate
           metabolism flavoprotein [Streptococcus mutans]
           Length = 145
           
 Score = 94.0 bits (230), Expect = 3e-18
 Identities = 55/146 (37%), Positives = 83/146 (56%), Gaps = 9/146 (6%)

Query: 19  KKIVLAIPGSIAAVECVKLARELIRHGAEVHAVMSPSATKIIHPYAMEFATGNPVITEIT 78
           KKI+LA+ GSIAA +   L+ +L + G  V+  M+ +A + I P  ++  + NPV + + 
Sbjct: 3   KKILLAVSGSIAAYKAADLSHQLTKLGYHVNVFMTNAAKQFIPPLTLQVLSKNPVYSNVM 62

Query: 79  GS-----IEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPHIPIM 133
                  I H+ LA     +ADL L+ PA+ANT++ +A G  D  VT+V       +P  
Sbjct: 63  KEDDPQVINHIALA----KQADLFLLPPASANTLAHLAHGFADNIVTSVALALPLEVPKF 118

Query: 134 IAPAMHESMYKHPIVRENIEKLKKLG 159
            APAM+  MY++PI + NI  LKK G
Sbjct: 119 FAPAMNTKMYENPITQSNITLLKKFG 144


>gi|9634784 ORF FPV114 HAL3 domain [Fowlpox virus]
           >gi|7271612|gb|AAF44458.1|AF198100_105 (AF198100) ORF
           FPV114 HAL3 domain [Fowlpox virus]
           Length = 183
           
 Score = 80.4 bits (195), Expect = 3e-14
 Identities = 58/185 (31%), Positives = 100/185 (53%), Gaps = 25/185 (13%)

Query: 20  KIVLAIPGSIAAVECVKLARELIR-HGAEVHAVMSPSATKIIHPYAMEFATGNPVITE-- 76
           KI++ I GS+AAV+   L +EL R    E+  V + ++ K    +  +   G P+ T+  
Sbjct: 5   KILIGITGSVAAVKLPDLIKELTRLENIELRIVATENSMK----FTDQKTIGIPIYTDKD 60

Query: 77  -------ITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPVTTVVTTAFPH 129
                  I   + H+EL       AD+ ++ P TANT++KIA GI D  +T++V     +
Sbjct: 61  EWTTWKKIPDPVLHIEL----RRWADVFIIAPLTANTLAKIANGICDNLLTSIVRAWDTN 116

Query: 130 IPIMIAPAMHESMYKHPIVRENIEKLKKLG---VEFIGPRI---EEGKAKVATIDEIVYR 183
            P++  PAM+  M++HPI  ++I+ LK +G   +E I  ++   + G   +A + EI YR
Sbjct: 117 KPLIFCPAMNTLMWEHPITEKHIDTLKYMGFIEIECIEKKLACGDVGNGAMAEVAEI-YR 175

Query: 184 VIKKL 188
           V++ +
Sbjct: 176 VVRDI 180


>pir||T37719 thymidylate synthase-like DNA metabolism protein - fission yeast
           (Schizosaccharomyces pombe) >gi|5725409|emb|CAB52423.1|
           (AL109770) thymidylate synthase-like DNA metabolism
           protein [Schizosaccharomyces pombe]
           Length = 625
           
 Score = 70.6 bits (170), Expect = 3e-11
 Identities = 65/212 (30%), Positives = 106/212 (49%), Gaps = 30/212 (14%)

Query: 12  KSRKLVGKK--IVLAIPGSIAAVECVKLARELIRH-GAEVHAVMSPSATKIIHPYAMEFA 68
           K R+L   K  I++A  GS+AA++   + + L+ + G +V  V++  A   +    +  A
Sbjct: 22  KERQLTDSKYHILVAATGSVAAIKLTLIVKSLLTYKGVDVQVVLTDPARNFVEKEDLT-A 80

Query: 69  TGNPVITE---------ITGSIEHVELAGEHENKADLILVCPATANTISKIACGIDDTPV 119
            G  V            +   I H+EL       A L+L+ P +ANT++K+A G+ D  +
Sbjct: 81  LGVNVYNNADDWKNWDGLECPITHIEL----RRWAHLLLIAPLSANTMAKMANGLCDNLL 136

Query: 120 TTVVTTAFPHIPIMIAPAMHESMYKHPIVRENIEKLKKL--GVEFIGPRIEE-------G 170
           T+++    P  PI++APAM+  M+ +PI +E++  + ++    EFI P IE+       G
Sbjct: 137 TSLIRAWAPLKPILLAPAMNTLMWTNPITQEHLSAISRIYKNSEFIMP-IEKVLACGDIG 195

Query: 171 KAKVATIDEIVYRVIKKLHPKTLEGKRVLITA 202
              +A    IV RV  KL    LE K VL  A
Sbjct: 196 MGGMAEWRNIVGRVADKLQ---LEQKSVLPNA 224


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.316    0.134    0.361 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 132070022
Number of Sequences: 2977
Number of extensions: 5215924
Number of successful extensions: 19023
Number of sequences better than 1.0e-10: 35
Number of HSP's better than  0.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 18875
Number of HSP's gapped (non-prelim): 36
length of query: 401
length of database: 189,106,746
effective HSP length: 62
effective length of query: 339
effective length of database: 152,000,552
effective search space: 51528187128
effective search space used: 51528187128
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 166 (69.1 bits)