BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1899 (moaa-like) DE:MOLYBDENUM COFACTOR BIOSYNTHESIS MOAA
HOMOLOG.
         (1042 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||H75112 molybdenum cofactor biosynthesis moaa homolog. PAB18...  2149  0.0
pir||E71020 hypothetical protein PH1458 - Pyrococcus horikoshii ...   875  0.0
gi|11499897 conserved hypothetical protein [Archaeoglobus fulgid...   469  e-131
emb|CAC11808.1| (AL445065) conserved hypothetical protein [Therm...   453  e-126
gb|AAK40578.1| Conserved hypothetical protein [Sulfolobus solfat...   398  e-109
pir||G72494 hypothetical protein APE2598 - Aeropyrum pernix (str...   395  e-108
pir||H69210 conserved hypothetical protein MTH831 - Methanobacte...   340  4e-92
sp|Q58036|Y619_METJA HYPOTHETICAL PROTEIN MJ0619 >gi|2128410|pir...   336  9e-91
sp|Q58454|YA54_METJA HYPOTHETICAL PROTEIN MJ1054 >gi|2129344|pir...   152  2e-35
dbj|BAA06142.2| (D29671) DNA-dependent DNA polymerase [Pyrococcu...   116  9e-25
sp|O59610|DPOL_PYRHO DNA POLYMERASE >gi|7446920|pir||C71210 prob...   112  2e-23
pir||B70797 probable transferase - Mycobacterium tuberculosis (s...   104  5e-21
sp|Q51334|DPOL_PYRSD DNA POLYMERASE (DEEP VENT DNA POLYMERASE) [...    95  5e-18
sp|Q58242|Y832_METJA HYPOTHETICAL PROTEIN MJ0832 >gi|2129243|pir...    88  4e-16
emb|CAC18555.1| (AJ245819) DNA polymerase and endonucleases [The...    85  5e-15
pir||B72665 hypothetical protein APE0745 - Aeropyrum pernix (str...    84  7e-15
sp|Q58815|YE20_METJA HYPOTHETICAL PROTEIN MJ1420 >gi|2127939|pir...    77  1e-12
pir||C71110 hypothetical protein PH0650 - Pyrococcus horikoshii ...    77  1e-12
sp|Q58446|RPA2_METJA DNA-DIRECTED RNA POLYMERASE SUBUNIT A" >gi|...    77  1e-12

>pir||H75112 molybdenum cofactor biosynthesis moaa homolog. PAB1899 - Pyrococcus
            abyssi (strain Orsay) >gi|5458128|emb|CAB49617.1|
            (AJ248285) MOLYBDENUM COFACTOR BIOSYNTHESIS MOAA HOMOLOG.
            [Pyrococcus abyssi]
            Length = 1042
            
 Score = 2149 bits (5508), Expect = 0.0
 Identities = 1042/1042 (100%), Positives = 1042/1042 (100%)

Query: 1    MAETVGEIPSGEKEFEASTKRLREIIEFPELSEDEFHELLKSASRGYGSPLPHRTYSLCP 60
            MAETVGEIPSGEKEFEASTKRLREIIEFPELSEDEFHELLKSASRGYGSPLPHRTYSLCP
Sbjct: 1    MAETVGEIPSGEKEFEASTKRLREIIEFPELSEDEFHELLKSASRGYGSPLPHRTYSLCP 60

Query: 61   ETRRVVPAVVWEKDGKVWITKKCPEGMITDLYYEDVELYYRFSRWKFEEKKLFSVNVENT 120
            ETRRVVPAVVWEKDGKVWITKKCPEGMITDLYYEDVELYYRFSRWKFEEKKLFSVNVENT
Sbjct: 61   ETRRVVPAVVWEKDGKVWITKKCPEGMITDLYYEDVELYYRFSRWKFEEKKLFSVNVENT 120

Query: 121  GVNCPFDCGLCARHRSHTSLLNIVLTNRCNLNCWYCFPPTEEAVFKFGDKVKIATFEEVA 180
            GVNCPFDCGLCARHRSHTSLLNIVLTNRCNLNCWYCFPPTEEAVFKFGDKVKIATFEEVA
Sbjct: 121  GVNCPFDCGLCARHRSHTSLLNIVLTNRCNLNCWYCFPPTEEAVFKFGDKVKIATFEEVA 180

Query: 181  KNFKFEHKVEIDGFKGEYSIPNDLYVLTFNDGKAEWTRVTKFLRRKHEGKIRVIKTKTGR 240
            KNFKFEHKVEIDGFKGEYSIPNDLYVLTFNDGKAEWTRVTKFLRRKHEGKIRVIKTKTGR
Sbjct: 181  KNFKFEHKVEIDGFKGEYSIPNDLYVLTFNDGKAEWTRVTKFLRRKHEGKIRVIKTKTGR 240

Query: 241  TIRTTPEHKFFVYKDGELVKKRADELEPGDELVLLWRFESEETLTEINLLEAFKDLPQEE 300
            TIRTTPEHKFFVYKDGELVKKRADELEPGDELVLLWRFESEETLTEINLLEAFKDLPQEE
Sbjct: 241  TIRTTPEHKFFVYKDGELVKKRADELEPGDELVLLWRFESEETLTEINLLEAFKDLPQEE 300

Query: 301  KEKVYVRGIKDLDLTPLKEKYGDKVYYWARQDSMPLSVFYELNVDLDKEFRLGRDATTYE 360
            KEKVYVRGIKDLDLTPLKEKYGDKVYYWARQDSMPLSVFYELNVDLDKEFRLGRDATTYE
Sbjct: 301  KEKVYVRGIKDLDLTPLKEKYGDKVYYWARQDSMPLSVFYELNVDLDKEFRLGRDATTYE 360

Query: 361  LPSKLKITPSLAKLIGYFVSDGNYSDKDLRITVGHEDVEKEIVNILEELGLPYSFLEWEG 420
            LPSKLKITPSLAKLIGYFVSDGNYSDKDLRITVGHEDVEKEIVNILEELGLPYSFLEWEG
Sbjct: 361  LPSKLKITPSLAKLIGYFVSDGNYSDKDLRITVGHEDVEKEIVNILEELGLPYSFLEWEG 420

Query: 421  KTKQIVIGSRLLRLVFKHVFKIPEGAPNKRLPEGFLSFPFEAKVALLSGLFNGDGYVVRG 480
            KTKQIVIGSRLLRLVFKHVFKIPEGAPNKRLPEGFLSFPFEAKVALLSGLFNGDGYVVRG
Sbjct: 421  KTKQIVIGSRLLRLVFKHVFKIPEGAPNKRLPEGFLSFPFEAKVALLSGLFNGDGYVVRG 480

Query: 481  EHHLSIGYASTSKGLIRDILYLLASLGIFARVYRVPKEKMKGANHDLYKLYIAGTDLVRL 540
            EHHLSIGYASTSKGLIRDILYLLASLGIFARVYRVPKEKMKGANHDLYKLYIAGTDLVRL
Sbjct: 481  EHHLSIGYASTSKGLIRDILYLLASLGIFARVYRVPKEKMKGANHDLYKLYIAGTDLVRL 540

Query: 541  VELLELREGHREKLGEIGNRKPARVKKIADFYIDVVDEVSEEEYSGYVYDLEVENEGHSF 600
            VELLELREGHREKLGEIGNRKPARVKKIADFYIDVVDEVSEEEYSGYVYDLEVENEGHSF
Sbjct: 541  VELLELREGHREKLGEIGNRKPARVKKIADFYIDVVDEVSEEEYSGYVYDLEVENEGHSF 600

Query: 601  VAADGILVSNCFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDL 660
            VAADGILVSNCFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDL
Sbjct: 601  VAADGILVSNCFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDL 660

Query: 661  IEIIKIAKEEGYDHVQLNTDGIKLAFDPELVKKIRQAGVNTLYLSYDGMTPQTNWKNHWE 720
            IEIIKIAKEEGYDHVQLNTDGIKLAFDPELVKKIRQAGVNTLYLSYDGMTPQTNWKNHWE
Sbjct: 661  IEIIKIAKEEGYDHVQLNTDGIKLAFDPELVKKIRQAGVNTLYLSYDGMTPQTNWKNHWE 720

Query: 721  IPLIFENVRKAGGPGIVLVPTLIRNVNDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVP 780
            IPLIFENVRKAGGPGIVLVPTLIRNVNDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVP
Sbjct: 721  IPLIFENVRKAGGPGIVLVPTLIRNVNDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVP 780

Query: 781  KKERQRFRITIAGAIKKIEEQTNGVISKDDWYPIPIAGHIARFFEVFTGSKYYMTSHFAC 840
            KKERQRFRITIAGAIKKIEEQTNGVISKDDWYPIPIAGHIARFFEVFTGSKYYMTSHFAC
Sbjct: 781  KKERQRFRITIAGAIKKIEEQTNGVISKDDWYPIPIAGHIARFFEVFTGSKYYMTSHFAC 840

Query: 841  GAATYVFLDREEKKVIPIPRFLDVEGFVEFLLEKAEEIEKARFKGLAKLKAIGETVFIKF 900
            GAATYVFLDREEKKVIPIPRFLDVEGFVEFLLEKAEEIEKARFKGLAKLKAIGETVFIKF
Sbjct: 841  GAATYVFLDREEKKVIPIPRFLDVEGFVEFLLEKAEEIEKARFKGLAKLKAIGETVFIKF 900

Query: 901  KQFYDEKNAPKGLDVLGLIKNAFVHGNYDALGKFHMNTLFLGMMHFMDEYNYDVERVERC 960
            KQFYDEKNAPKGLDVLGLIKNAFVHGNYDALGKFHMNTLFLGMMHFMDEYNYDVERVERC
Sbjct: 901  KQFYDEKNAPKGLDVLGLIKNAFVHGNYDALGKFHMNTLFLGMMHFMDEYNYDVERVERC 960

Query: 961  VIHYAMPDGRIVPFCTFNVIPELYRDKVQRQFSYSWEEWKKLHPDWDYMKDKYVRTKEFV 1020
            VIHYAMPDGRIVPFCTFNVIPELYRDKVQRQFSYSWEEWKKLHPDWDYMKDKYVRTKEFV
Sbjct: 961  VIHYAMPDGRIVPFCTFNVIPELYRDKVQRQFSYSWEEWKKLHPDWDYMKDKYVRTKEFV 1020

Query: 1021 EKMKKSELYRKTYIDIVNYFER 1042
            EKMKKSELYRKTYIDIVNYFER
Sbjct: 1021 EKMKKSELYRKTYIDIVNYFER 1042


>pir||E71020 hypothetical protein PH1458 - Pyrococcus horikoshii
            >gi|3257882|dbj|BAA30565.1| (AP000006) 587aa long
            hypothetical protein [Pyrococcus horikoshii]
            Length = 587
            
 Score =  875 bits (2237), Expect = 0.0
 Identities = 410/432 (94%), Positives = 427/432 (97%)

Query: 611  CFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDLIEIIKIAKEE 670
            CFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDLIEIIKIAKEE
Sbjct: 156  CFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDLIEIIKIAKEE 215

Query: 671  GYDHVQLNTDGIKLAFDPELVKKIRQAGVNTLYLSYDGMTPQTNWKNHWEIPLIFENVRK 730
            GYDH+QLNTDGIKLAFDPELVKK+R+AGVNTLYLSYDGMTPQTNWKNHWEIPLIFENVRK
Sbjct: 216  GYDHIQLNTDGIKLAFDPELVKKLREAGVNTLYLSYDGMTPQTNWKNHWEIPLIFENVRK 275

Query: 731  AGGPGIVLVPTLIRNVNDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVPKKERQRFRIT 790
            AGGPGIVLVPTLIRN+NDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVP+KERQRFRIT
Sbjct: 276  AGGPGIVLVPTLIRNINDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVPRKERQRFRIT 335

Query: 791  IAGAIKKIEEQTNGVISKDDWYPIPIAGHIARFFEVFTGSKYYMTSHFACGAATYVFLDR 850
            IAGAIKKIEEQTNGVI+K+DWYPIPIAGHIARFFE FTG KYYMTSHFACGAATYVFLDR
Sbjct: 336  IAGAIKKIEEQTNGVIAKEDWYPIPIAGHIARFFEAFTGRKYYMTSHFACGAATYVFLDR 395

Query: 851  EEKKVIPIPRFLDVEGFVEFLLEKAEEIEKARFKGLAKLKAIGETVFIKFKQFYDEKNAP 910
            EEKKVIPIPRF+DV+GFVEFL+EKAEEIEKARFK LAKLKAIGET+F+KFKQFYDEKNAP
Sbjct: 396  EEKKVIPIPRFIDVDGFVEFLVEKAEEIEKARFKSLAKLKAIGETIFVKFKQFYDEKNAP 455

Query: 911  KGLDVLGLIKNAFVHGNYDALGKFHMNTLFLGMMHFMDEYNYDVERVERCVIHYAMPDGR 970
            KGLDVLGLIKNAFVHG YDALGKFHMNTLF+GMMHFMDEYNYDVERVERCVIHYAMPDGR
Sbjct: 456  KGLDVLGLIKNAFVHGTYDALGKFHMNTLFIGMMHFMDEYNYDVERVERCVIHYAMPDGR 515

Query: 971  IVPFCTFNVIPELYRDKVQRQFSYSWEEWKKLHPDWDYMKDKYVRTKEFVEKMKKSELYR 1030
            IVPFCTFNVIPE+YRDKVQRQFSYSWEEWKKLHPDWDY KDKY+RTKEFVEKMKKSE+Y+
Sbjct: 516  IVPFCTFNVIPEIYRDKVQRQFSYSWEEWKKLHPDWDYKKDKYIRTKEFVEKMKKSEVYK 575

Query: 1031 KTYIDIVNYFER 1042
            KTYIDIVNYFER
Sbjct: 576  KTYIDIVNYFER 587


 Score =  319 bits (810), Expect = 8e-86
 Identities = 150/210 (71%), Positives = 176/210 (83%), Gaps = 11/210 (5%)

Query: 1   MAETVGEIPSGEKEFEASTKRLREIIEFPELSEDEFHELLKSASRGYGSPLPHRTYSLCP 60
           MAET+GE+PSGEKEFEASTK +REIIEFPE++E+EF++LLKSAS+GYGSPLPHRTYSLCP
Sbjct: 1   MAETLGEVPSGEKEFEASTKHVREIIEFPEMTEEEFNKLLKSASKGYGSPLPHRTYSLCP 60

Query: 61  ETRRVVPAVVWEKDGKVWITKKCPEGMITDLYYEDVELYYRFSRWKFEEKKLFSVNVENT 120
           E+RRVVPAVVWEKDGKVWITKKCPEGMITDLYYEDVELYYRFS+W+FEEKKLFS NV NT
Sbjct: 61  ESRRVVPAVVWEKDGKVWITKKCPEGMITDLYYEDVELYYRFSKWRFEEKKLFSANVSNT 120

Query: 121 GVNCPFDCGLCARHRSHTSLLNIVLTNRCNLNCWYCFPPTEEAVFKFGDKVKIATFEEV- 179
           G+NCPFDCGLC RHRSHTSL+NIVLTNRCNL+CWYCF    E     G+ +   T E++ 
Sbjct: 121 GINCPFDCGLCPRHRSHTSLINIVLTNRCNLSCWYCFFYARE-----GEPIYEPTLEQIR 175

Query: 180 --AKNFKFEHKVEIDGFK---GEYSIPNDL 204
              +N K EH +  +  +   GE ++ +DL
Sbjct: 176 MMLRNAKKEHPIGANAVQFTGGEPTLRDDL 205


>gi|11499897 conserved hypothetical protein [Archaeoglobus fulgidus]
            >gi|7451255|pir||D69539 conserved hypothetical protein
            AF2316 - Archaeoglobus fulgidus
            >gi|2648203|gb|AAB88940.1| (AE000944) conserved
            hypothetical protein [Archaeoglobus fulgidus]
            Length = 518
            
 Score =  469 bits (1194), Expect = e-131
 Identities = 226/392 (57%), Positives = 289/392 (73%), Gaps = 9/392 (2%)

Query: 611  CFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDLIEIIKIAKEE 670
            CFFYAR    +YEPT+EQIR M+R AK   PIG NAVQ TGGEPTLRDDLI+II++ KEE
Sbjct: 117  CFFYARRAGYVYEPTIEQIREMVRKAKNMKPIGCNAVQLTGGEPTLRDDLIDIIRMIKEE 176

Query: 671  GYDHVQLNTDGIKLAFDPELVKKIRQAGVNTLYLSYDGMTPQTNWKNHWEIPLIFENVRK 730
            GYDH+QLNT+GI+LA DP+   ++R AGVNT+YLS+DG+  +TN KNH EIP I EN R+
Sbjct: 177  GYDHIQLNTNGIRLAEDPDFALRVRVAGVNTVYLSFDGVDEKTNPKNHHEIPKILENCRR 236

Query: 731  AGGPGIVLVPTLIRNVNDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVPKKERQRFRIT 790
            A   G+VLVPT+I+ VNDH+ G II F   ++DIVRGVNFQP+SLVG +P+KER++FRIT
Sbjct: 237  A-QLGLVLVPTVIKGVNDHQLGDIIRFAAENIDIVRGVNFQPVSLVGSMPRKEREQFRIT 295

Query: 791  IAGAIKKIEEQTNGVISKDDWYPIPIAGHIARFFEVFTGS-KYYMTSHFACGAATYVFLD 849
            I   IK IEEQTNG I ++D+YP+P    I+RF E  TG  +Y +T+HFACG ATY+F  
Sbjct: 296  IPDCIKAIEEQTNGEIGREDFYPVPSVVPISRFVEALTGQPQYELTTHFACGMATYIF-- 353

Query: 850  REEKKVIPIPRFLDVEGFVEFLLEKAEEIEKARFKGLAKLKAIGETVFIKFKQFYDEKNA 909
            ++  ++IPI RF+DVEG  EFL EKAEEI K+R K +  +K I     I  ++F D   A
Sbjct: 354  KDNGRLIPITRFVDVEGLFEFLNEKAEEIAKSRMKTIRAIKDI-----IDLRKFVDTSKA 408

Query: 910  PKGLDVLGLIKNAFVHGNYDALGKFHMNTLFLGMMHFMDEYNYDVERVERCVIHYAMPDG 969
            PKG ++  ++    +  +Y  LG+FH+ +LF+GMMHF D YNYD+ RVERC IHY  PDG
Sbjct: 409  PKGFNIAKILYEVLIKHDYSTLGEFHVKSLFIGMMHFQDLYNYDIARVERCEIHYGSPDG 468

Query: 970  RIVPFCTFNVIPELYRDKVQRQFSYSWEEWKK 1001
            RI+PFCTFNVIPE YRD +  ++    EEW+K
Sbjct: 469  RIIPFCTFNVIPERYRDAIHEKYGIPIEEWEK 500


 Score =  117 bits (290), Expect = 7e-25
 Identities = 59/136 (43%), Positives = 85/136 (62%), Gaps = 4/136 (2%)

Query: 51  LPHRTYSLCPETRRVVPAVVWEKDGKVWITKKCPE-GMITDLYYEDVELYYRFSRWKFEE 109
           LP++T SLCPE  +++ A V+E++GKV I K C E G   D+Y+ D E++ + +R+  + 
Sbjct: 13  LPYKTKSLCPECLKILEAEVYEENGKVMIRKVCEEHGEFVDVYWGDAEMFKKAARFAADG 72

Query: 110 KKLFSVNVENTGVNCPFDCGLCARHRSHTSLLNIVLTNRCNLNCWYCFPPTEEAVFKFGD 169
             + +   +NT   CPF CGLC  H+SHT+LLNIVLTNRC+L CWYCF     A + +  
Sbjct: 73  HGISTPITQNT--TCPFSCGLCNNHKSHTALLNIVLTNRCDLACWYCFFYARRAGYVYEP 130

Query: 170 KV-KIATFEEVAKNFK 184
            + +I      AKN K
Sbjct: 131 TIEQIREMVRKAKNMK 146


>emb|CAC11808.1| (AL445065) conserved hypothetical protein [Thermoplasma acidophilum]
            Length = 571
            
 Score =  453 bits (1153), Expect = e-126
 Identities = 215/423 (50%), Positives = 299/423 (69%), Gaps = 6/423 (1%)

Query: 611  CFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDLIEIIKIAKEE 670
            CFFYA+E EPIYEPT +QIRMMLR  K E P+GANAVQ TGGEPT+RDD+I+I++IA+EE
Sbjct: 126  CFFYAKENEPIYEPTQDQIRMMLRRMKNEKPVGANAVQITGGEPTMRDDIIDIVRIAREE 185

Query: 671  GYDHVQLNTDGIKLAFDPELVKKIRQAGVNTLYLSYDGMTPQTNWKNHWEIPLIFENVRK 730
            GYDHVQLNT+ ++ AFDP+ V+++R+AG N +Y S+DG TP++N KN WEIP   EN +K
Sbjct: 186  GYDHVQLNTNSVRAAFDPDFVRRVREAGSNVIYTSFDGPTPRSNPKNFWEIPAALENYKK 245

Query: 731  AGGPGIVLVPTLIRNVNDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVPKKERQRFRIT 790
            A   G+VLVPT+I  VND   G II FGL+++D+VR VNFQP+SLVGR+P + R + RIT
Sbjct: 246  A-PLGVVLVPTVIGGVNDMYLGDIIRFGLSNIDVVRAVNFQPVSLVGRMPDRARAKQRIT 304

Query: 791  IAGAIKKIEEQTNGVISKDDWYPIPIAGHIARFFEVFTGSKYYMTS-HFACGAATYVFLD 849
            I GAIKKIE+QT+G+I ++D++ +P    ++ F     G   Y  S H+ACG  TY+F  
Sbjct: 305  IPGAIKKIEQQTDGLIGREDFFTVPSTASVSNFVAALKGRPTYKLSIHYACGMGTYLF-- 362

Query: 850  REEKKVIPIPRFLDVEGFVEFLLEKAEEIEKARFKGLAKLKAIGETVFIKFKQFYDEKNA 909
            ++++KVIP+ RF+DV+G  E++   A+EI  + FK L K+++  + ++   K+F D + A
Sbjct: 363  KDDEKVIPVTRFVDVKGMFEYIQNLADEIGDSTFKSLRKVESTAKLLY-NLKKFVDYEKA 421

Query: 910  PKGLDVLGLIKNAFVHGNYDALGKFHMNTLFLGMMHFMDEYNYDVERVERCVIHYAMPDG 969
            PK   +  ++ NAF  G+Y  L  FH  ++F+G MHF D Y YDV+RVERC IHYAMPDG
Sbjct: 422  PKDFKLKDMVYNAFTEGDYHGLKAFHYKSMFIGFMHFQDPYTYDVDRVERCDIHYAMPDG 481

Query: 970  RIVPFCTFNVIPELYRDKVQRQFSYSWEEWKKLHPDWDYMKDKYVRTKEFVEKMKKSELY 1029
            R++PFC FNVIPELYRD  QR++S   + +++        K+KY R     +K +    Y
Sbjct: 482  RVIPFCAFNVIPELYRDSTQRKYSIPAKVYEE-KTGRSLKKEKYFREYSLEDKKRIIAFY 540

Query: 1030 RKT 1032
             ++
Sbjct: 541  ERS 543


 Score =  101 bits (249), Expect = 5e-20
 Identities = 48/113 (42%), Positives = 72/113 (63%), Gaps = 10/113 (8%)

Query: 55  TYSLCPET-------RRVVPAVVWEKDGKVWITKKCPE-GMITDLYYEDVELYYRFSRWK 106
           T SLCP         +  +PA+V+E+ G+V + K+CPE G+  + Y+ED E++    +W+
Sbjct: 15  TESLCPGCVDEEKFDQMRIPAIVYEEGGEVKLIKECPEHGVTVEKYWEDYEMFEEAKKWQ 74

Query: 107 FEEKKLFSVNVEN--TGVNCPFDCGLCARHRSHTSLLNIVLTNRCNLNCWYCF 157
               K+ + NV    + + CP  CGLC +H+SHT L NIV+TNRC+L+CWYCF
Sbjct: 75  DPGVKILNPNVAYYASKIVCPTHCGLCVKHKSHTGLGNIVVTNRCDLSCWYCF 127


>gb|AAK40578.1| Conserved hypothetical protein [Sulfolobus solfataricus]
            Length = 582
            
 Score =  398 bits (1012), Expect = e-109
 Identities = 201/434 (46%), Positives = 283/434 (64%), Gaps = 20/434 (4%)

Query: 611  CFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDLIEIIKIAKEE 670
            CFFYA +   +YEPTLEQI+ M+   KK+       +Q TGGEPTLR+D+IEIIK+ +E 
Sbjct: 152  CFFYAEKAGYVYEPTLEQIKFMVDQLKKQDI--TLVIQVTGGEPTLREDIIEIIKMLREN 209

Query: 671  GYDHVQLNTDGIKLAF----DPELVKK----IRQAGVNTLYLSYDGMTPQTNWKNHWEIP 722
            G  H+QLN+ G   A     DP+   K    +R+AGVNT+Y+S+DG T +TN KNHWEIP
Sbjct: 210  GVKHIQLNSWGGTFAKLYLEDPDKAIKYARALREAGVNTVYMSFDGTTRKTNPKNHWEIP 269

Query: 723  LIFENVRKAGGPGIVLVPTLIRNVNDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVPKK 782
               E  R+AG   +VLVPT+I+ VND++ G I+ F   ++D+VR VNFQP+SL G + + 
Sbjct: 270  YTLEVFRRAGMTSVVLVPTVIKTVNDNDLGNIVKFAAYNMDVVRSVNFQPVSLTGMMKRN 329

Query: 783  ERQRFRITIAGAIKKIEEQTNGVISKDDWYPIPIAGHIARFFEVFTGSKYY-MTSHFACG 841
             R +FRITI   IK IEEQT+G I+KD WYPI  +   +R  E  TG + + M +H +CG
Sbjct: 330  MRAKFRITIPEVIKNIEEQTDGEITKDSWYPIGTSVVFSRLVEALTGKEQFEMANHPSCG 389

Query: 842  AATYVFLD--REEKKVIPIPRFLDVEGFVEFLLEKAEEIEKARFKGLAKLKAIGETVFIK 899
            A TYV+++    E   IPI +F+D+EG +E+L EK EE+ +      A    +   V   
Sbjct: 390  AGTYVYVEWRNHEPHFIPISKFIDLEGLLEYLKEKEEELREG-----ANKVWVASKVLYS 444

Query: 900  FKQFYDEKNAPKGLDVLGLIKNAFVHGNYDALGKFHMNTLFLGMMHFMDEYNYDVERVER 959
             ++F D++  PK  DV  ++ N  +H NY+ALG++H  TLFLG MHFMD YNYDV+RV R
Sbjct: 445  IRKFIDKEQGPKDFDVYKMLYNIIIHHNYEALGEWHYRTLFLGSMHFMDLYNYDVQRVMR 504

Query: 960  CVIHYAMPDGRIVPFCTFNVIPELYRDKVQRQFSYSWEEWKKLHPDWDYMKDKYVRTKEF 1019
            C IHY +PDGR++PFCT+NV+ +LYRDKV R++    ++W K H + + + D  ++ K  
Sbjct: 505  CDIHYVVPDGRVIPFCTYNVLNDLYRDKVLREYQIPLDKWTKEHGE-NSLGDA-IKYKRI 562

Query: 1020 VEKMKKSELYRKTY 1033
               ++ SE+Y+ TY
Sbjct: 563  ASTLENSEIYKNTY 576


 Score =  123 bits (306), Expect = 9e-27
 Identities = 59/132 (44%), Positives = 87/132 (65%), Gaps = 15/132 (11%)

Query: 48  GSPLP---------HRTYSLCPETRRVVPAVVWEKDGKVWITKKCPE-GMITDLYYEDVE 97
           G PLP           T+SLCP   R++PA ++EK+GK++I K CPE G   DLYY D  
Sbjct: 35  GGPLPTLAKDEKLVRVTHSLCPACYRLLPATIFEKEGKLFIRKICPEHGEFEDLYYADSS 94

Query: 98  LYYRFSRWKFEEK--KLFSVNVENTGVNCPFDCGLCARHRSHTSLLNIVLTNRCNLNCWY 155
           LYY+F  W++E K  K+  V++++    CP++CGLC  H  H++L+N+V+TNRC+L+CWY
Sbjct: 95  LYYKFDYWEYEGKGPKVPYVDLKSP---CPYNCGLCPMHHQHSALVNLVITNRCDLSCWY 151

Query: 156 CFPPTEEAVFKF 167
           CF   E+A + +
Sbjct: 152 CFFYAEKAGYVY 163


>pir||G72494 hypothetical protein APE2598 - Aeropyrum pernix (strain K1)
            >gi|5106304|dbj|BAA81615.1| (AP000064) 610aa long
            hypothetical protein [Aeropyrum pernix]
            Length = 610
            
 Score =  395 bits (1004), Expect = e-108
 Identities = 206/469 (43%), Positives = 307/469 (64%), Gaps = 35/469 (7%)

Query: 595  NEGHSFVAADGILVSN--------CFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANA 646
            +E HS  A   I+V+N        CFFYA     IYEP++EQI+ M+R   ++   G++ 
Sbjct: 137  HENHS--ALVNIVVTNRCDLSCFYCFFYAERAGYIYEPSIEQIKFMVRQVARQRQ-GSDV 193

Query: 647  ---VQFTGGEPTLRDDLIEIIKIAKEEGYDHVQLNTDGIKLAF----DP----ELVKKIR 695
               +Q TGGEPT+R+DL++++K  +E G  ++QLNT+GI +A     +P    + V+ +R
Sbjct: 194  HVNIQITGGEPTVREDLVDVVKAIREAGAHYIQLNTNGINVARRYLDNPPGAIDYVRSLR 253

Query: 696  QAGVNTLYLSYDGMTPQTNWKNHWEIPLIFENVRKAGGPGIVLVPTLIRNVNDHEAGAII 755
            +AGV+ +Y+S+DG+TP+ NWKNH+E P   +  ++ G   +VLVPT+IR +NDHE G II
Sbjct: 254  EAGVSVVYMSFDGVTPKVNWKNHYEAPFALKAFQEGGLDNVVLVPTVIRTINDHEVGDII 313

Query: 756  NFGLNHLDIVRGVNFQPISLVGRVPKKERQRFRITIAGAIKKIEEQTNGVISKDDWYPIP 815
             F   H+D+VRGVNFQP+SL G + K ER+R RITI   IK+IEEQT+G I  D WYP+P
Sbjct: 314  RFAGKHIDVVRGVNFQPVSLTGMMRKHERERMRITIPDVIKRIEEQTDGQIPMDAWYPVP 373

Query: 816  IAGHIARFFEVFTGSKY-YMTSHFACGAATYVF-LDREE----KKVIPIPRFLDVEGFVE 869
            +     +  +  TG  Y  +++H ACG+ATYVF L+R+     ++ +PI   +DVEGF+E
Sbjct: 374  VVAKFVKAIDALTGKLYDTLSNHPACGSATYVFALERDRYGVPRRFLPITEVIDVEGFIE 433

Query: 870  FLLEKAEEIEKARFKGLAKLKAIGETVFIKFKQFYDEKNAPKGLDVLGLIKNAFVHGNYD 929
            FL E+  ++E    + L++LK   E V+ + ++F D    P+ LD+  LI + F+  NY+
Sbjct: 434  FLDEERIKLEHNSGR-LSRLKVAAEIVW-RARRFVDFDRMPRDLDIYKLIVSIFLRKNYE 491

Query: 930  ALGKFHMNTLFLGMMHFMDEYNYDVERVERCVIHYAMPDGRIVPFCTFNVIPELYRDKVQ 989
            A+  FH  TLFLGMMHFMD YNYD+ RV RC IHYA+PDGR+VPFC FNV+ ++YRD VQ
Sbjct: 492  AIKTFHKKTLFLGMMHFMDRYNYDITRVRRCNIHYALPDGRLVPFCAFNVLEDIYRDNVQ 551

Query: 990  RQFSYSWEEWKKLHPDWDYMKDKYVRTKEFVEKMKKSELYRKTYIDIVN 1038
            ++F+ +    K L        +KY R + +++++ +S +YR+ Y  I++
Sbjct: 552  KRFAKA----KNLRIKGFNPGEKYDR-RRYIKRILESPIYREAYRGIID 595


 Score =  108 bits (268), Expect = 3e-22
 Identities = 64/173 (36%), Positives = 95/173 (53%), Gaps = 14/173 (8%)

Query: 46  GYGSPLP---------HRTYSLCPETRRVVPAVVWEKDGKVWITKKCPE-GMITDLYYED 95
           G G PLP           T S+CP   R++PAV+  + G+++I KKCPE G I DLYY D
Sbjct: 38  GVGGPLPAVREGERLIRYTGSICPYCLRLLPAVIVARGGRLYIRKKCPEHGEIEDLYYGD 97

Query: 96  VELYYRFSRWKFEEKKLFSVNVENTGVN-CPFDCGLCARHRSHTSLLNIVLTNRCNLNCW 154
              Y+R  +W+     L       T    CP+ CGLC+ H +H++L+NIV+TNRC+L+C+
Sbjct: 98  ERFYWRQMKWEETGLGLSGAGPYTTATAPCPYACGLCSLHENHSALVNIVVTNRCDLSCF 157

Query: 155 YCFPPTEEAVFKFGDKVKIATF--EEVAKNFK-FEHKVEIDGFKGEYSIPNDL 204
           YCF   E A + +   ++   F   +VA+  +  +  V I    GE ++  DL
Sbjct: 158 YCFFYAERAGYIYEPSIEQIKFMVRQVARQRQGSDVHVNIQITGGEPTVREDL 210


>pir||H69210 conserved hypothetical protein MTH831 - Methanobacterium
            thermoautotrophicum (strain Delta H)
            >gi|2621921|gb|AAB85329.1| (AE000860) molybdenum cofactor
            biosynthesis MoaA homolog [Methanobacterium
            thermoautotrophicum]
            Length = 497
            
 Score =  340 bits (864), Expect = 4e-92
 Identities = 179/396 (45%), Positives = 253/396 (63%), Gaps = 15/396 (3%)

Query: 611  CFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDLIEIIKIAKEE 670
            CF  A     IYEPT E+IR MLRN ++  P+   A+Q+ GGEPT+R D+++++K+A+EE
Sbjct: 110  CFANAAVSNYIYEPTYEEIREMLRNLRRNRPVPTPAIQYAGGEPTVRKDIVDLVKLAREE 169

Query: 671  GYDHVQLNTDGIKLAFDPELVKKIRQAGVNTLYLSYDGMTPQ----TNWKNHWEIPL-IF 725
            G+ HVQ+ T+G++LA  PEL  ++R+AG+NT+YL +DG+T +    +  KN   I L   
Sbjct: 170  GFTHVQIATNGVRLARKPELAAELREAGLNTVYLQFDGVTEEPYITSRGKNLLPIKLQAI 229

Query: 726  ENVRKAGGPGIVLVPTLIRNVNDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVPKKERQ 785
            EN RK  G GIVLVPTL+R +ND++ G II F ++++DI+RGVNFQP+S  GR P    +
Sbjct: 230  ENCRKV-GLGIVLVPTLVRGLNDNQVGDIIRFAIDNIDIIRGVNFQPVSFAGRTPADRVE 288

Query: 786  RFRITIAGAIKKIEEQTNGVISKDDWYPIPIAGHIARFFEVFTGS-KYYMTSHFACGAAT 844
              RITI    K +E QT   IS DD+YP      I+ F     G  +   T H  CG AT
Sbjct: 289  EQRITIPDFQKLVEAQTGSEISMDDFYPASSVRPISDFVAAIEGEPQVTFTCHQHCGTAT 348

Query: 845  YVFLDREEKKVIPIPRFLDVEGFVEFLLEKAEEIEKARFKGLAKLKAIGETVFIKFKQFY 904
            Y+FL  E+ K+IPI RF+DV+ F E L +  +EIE+      AK + I  +  I+  +  
Sbjct: 349  YIFL--EDDKIIPITRFIDVDRFFEVLEKGKDEIEEGGI--AAKARVIARSA-IELPKTL 403

Query: 905  DEKNAPKGLDVLGLIKNAFVHGNYDALGKFHMNTLFLGMMHFMDEYNYDVERVERCVIHY 964
            D+  AP+ +D+  ++ + F   +Y ALG+FH NTL +  MHFMD +N+D++RV RCVIHY
Sbjct: 404  DKSEAPESVDIKRILTSIFKERSYTALGEFHYNTLLISCMHFMDPWNFDIDRVRRCVIHY 463

Query: 965  AMPDGRIVPFCTFNVIPELYRDKVQRQFSYSWEEWK 1000
            A+PDGRIVPFCT N    ++R  V+R F+    E K
Sbjct: 464  ALPDGRIVPFCTMN---SIHRADVERHFAKPLNESK 496


 Score = 88.9 bits (217), Expect = 3e-16
 Identities = 45/105 (42%), Positives = 63/105 (59%), Gaps = 2/105 (1%)

Query: 54  RTYSLCPETRRVVPAVVWEKDGKVWITKKCPE-GMITDLYYEDVELYYRFSRWKFEEKKL 112
           +T SLCPE  R V A V+E +G+V I K+CPE G   ++Y+ + ++Y++   +  E + L
Sbjct: 8   KTRSLCPECLRPVDAEVFEDEGRVLIRKECPEHGKFENVYWSNSKIYHKAEEYDEEGEGL 67

Query: 113 FSVNVENTGVNCPFDCGLCARHRSHTSLLNIVLTNRCNLNCWYCF 157
            +   +     CP DCGLC  H SHT L  I +TNRCNL C  CF
Sbjct: 68  LNPQTDPLK-GCPMDCGLCPEHESHTVLGLIDVTNRCNLKCPICF 111


>sp|Q58036|Y619_METJA HYPOTHETICAL PROTEIN MJ0619 >gi|2128410|pir||C64377 hypothetical
            protein MJ0619 - Methanococcus jannaschii
            >gi|1591330|gb|AAB98614.1| (U67510) conserved
            hypothetical protein [Methanococcus jannaschii]
            Length = 506
            
 Score =  336 bits (852), Expect = 9e-91
 Identities = 179/401 (44%), Positives = 261/401 (64%), Gaps = 18/401 (4%)

Query: 611  CFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDLIEIIKIAKEE 670
            CF  A +   +YEP+ E I+ M+ N +KE P    A+QF GGEPT+R DL E+IK+A++ 
Sbjct: 105  CFANANKSGKVYEPSFEDIKRMMENLRKEIP-PTPAIQFAGGEPTVRSDLPELIKLARDM 163

Query: 671  GYDHVQLNTDGIKLAFDPELVKKIRQAGVNTLYLSYDGMTPQ----TNWKNHWEIPL-IF 725
            G+ HVQL T+GIKL  +   +KK+++AG++T+YL +DG++ +       KN   I   + 
Sbjct: 164  GFLHVQLATNGIKLK-NINYLKKLKEAGLSTIYLQFDGISEKPYLVARGKNLLPIKQKVI 222

Query: 726  ENVRKAGGPGIVLVPTLIRNVNDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVPKKERQ 785
            EN +K G   +VLVPTL+R VND+E G II +   ++D+VRG+NFQP+S  GRV +K   
Sbjct: 223  ENCKKVGFDSVVLVPTLVRGVNDNEVGGIIRYAAENVDVVRGINFQPVSFTGRVDEKTLL 282

Query: 786  RFRITIAGAIKKIEEQTNGVISKDDWYPIPIAGHIARFFEVFTGS-KYYMTSHFACGAAT 844
              RITI   IK +EEQT+G I+++D+YP+P    I+   E  T   K  ++SH  CG +T
Sbjct: 283  EGRITIPDFIKLVEEQTDGEITEEDFYPVPSVAPISVLVEKLTNDRKPTLSSHQHCGTST 342

Query: 845  YVFLDREEKKVIPIPRFLDVEGFVEFLLEKAEEIEKARFKGLAKLKAIGETVFIKFKQFY 904
            YVF+D E+ K+IPI RF+DVEGF+E + EK EEI K++   +  +K +GE + +K     
Sbjct: 343  YVFVD-EDGKLIPITRFIDVEGFLEIVKEKIEEIGKSK---MHDVKVLGE-IALKLPSLI 397

Query: 905  DEKNAPKGLDVLGLIK--NAFVHGNYDALGKFHMNTLFLGMMHFMDEYNYDVERVERCVI 962
            D   APK +++  +I    + +  +Y AL + H + L +  MHFMD YN+DV+RV RC I
Sbjct: 398  DLDKAPKSVNIKKIIDLILSVLKSDYSALAELHYHMLMISCMHFMDAYNFDVKRVMRCCI 457

Query: 963  HYAMPDGRIVPFCTFNVIPELYRDKVQRQFSYSWEEWKKLH 1003
            HYA PD RI+PFCT+N    L+R +V+ +FS   EEWK++H
Sbjct: 458  HYATPDDRIIPFCTYNT---LHRQEVEEKFSIPLEEWKRMH 495


 Score =  108 bits (266), Expect = 5e-22
 Identities = 57/131 (43%), Positives = 79/131 (59%), Gaps = 12/131 (9%)

Query: 54  RTYSLCPETRRVVPAVVWEKDGKVWITKKCPE-GMITDLYYEDVELYYRFSRWKFEEKKL 112
           +T SLCP   + +PA + E+DGK+ I K CPE G   D+Y+ D ELY +F +++F  K  
Sbjct: 4   KTLSLCPICLKRIPATILEEDGKIIIKKTCPEHGEFKDIYWGDAELYKKFDKYEFIGK-- 61

Query: 113 FSVNVENTGVN--CPFDCGLCARHRSHTSLLNIVLTNRCNLNCWYCFPPTEEAVFKFGDK 170
             + V NT V   CP+DCGLC  H+S T L NI +TNRCNLNC  CF    ++      K
Sbjct: 62  --IEVTNTKVKNGCPYDCGLCPNHKSTTILANIDVTNRCNLNCPICFANANKS-----GK 114

Query: 171 VKIATFEEVAK 181
           V   +FE++ +
Sbjct: 115 VYEPSFEDIKR 125


>sp|Q58454|YA54_METJA HYPOTHETICAL PROTEIN MJ1054 >gi|2129344|pir||E64431 UDPglucose
           6-dehydrogenase (EC 1.1.1.22) (intein-containing) -
           Methanococcus jannaschii >gi|1591706|gb|AAB99056.1|
           (U67548) UDP-glucose dehydrogenase, putative
           [Methanococcus jannaschii]
           Length = 895
           
 Score =  152 bits (381), Expect = 2e-35
 Identities = 130/481 (27%), Positives = 225/481 (46%), Gaps = 49/481 (10%)

Query: 156 CFPPTEEAVFKFGDKVKIATFEEVAKNFKFEHKVEIDGFKGEYSIPNDLYVLTFNDGKAE 215
           CF P E      G  ++  TF+E+   F+ E K             +++ +L+F+  K  
Sbjct: 261 CFHPDEVLFIDRGRGLECITFKEL---FELEDK-------------DNVKILSFDGEKLS 304

Query: 216 WTRVTKFLRRKHEGKIRVIKTKTGRTIRTTPEHKFFVYKDGELVKKRADELEPGDELVLL 275
             ++    +R +   +  ++   GR I+ T +H   + +DGEL  K   +++ GD+++L 
Sbjct: 305 LKKLKLASKRYYNDDLITLRFNLGREIKITKDHPVVILEDGELKIKLTSDVKEGDKVILP 364

Query: 276 WRFESEETLTEINLLEAFKDLPQEEKEKVYVRGIKDLDLTPLKEKYGDKVYYWAR----- 330
           +    EE   EI++LE        EK  ++ + +   +   +K    +K  +  +     
Sbjct: 365 YGNFGEEREIEIDILEELSKTDLIEKVWIHNKDLATNEFNIIKPYLSNKYPHDVKRNGTI 424

Query: 331 --QDSMPLSVFYELNVDLDKEFRLGRDATTYELPSKLKITPSLAKLIGYFVSDGNYSDKD 388
             +D +P+    +     ++ F     +TT  +P K+KI    A+LIGY++S+G +  KD
Sbjct: 425 RAKDILPIKEILDKYGSKNRLFTAKSKSTT--IPYKIKIDKDFARLIGYYLSEG-WISKD 481

Query: 389 ------------LRITVGHEDVEKEIVNILEELGLPYSFLEWEGKTKQIVIGSRLLRLVF 436
                       L   +  E+   ++ NIL +LG+ Y     +G +  I+I S++L  VF
Sbjct: 482 YGRNGVVRKRIGLCFGIHEEEYINDVKNILNKLGIKYIEKIKDG-SHSILISSKILAYVF 540

Query: 437 KHVFKIPEGAPNKRLPEGFLSFPFEAKVALLSGLFNGDGYVVR--GEHHLSIGYASTSKG 494
           +++        NK +P    +   E K   L GLF GDG +VR     +L+I +A+ SK 
Sbjct: 541 ENILNCGINCYNKNIPPQMFNAKEEIKWEFLKGLFRGDGGIVRLNNNKNLNIEFATVSKK 600

Query: 495 LIRDILYLLASLGIFARVYRVPKEKMKGANHDLYKLYIAGTDLVRLV-ELLELREGHREK 553
           +   +L LL  LGI A V +    K   +    Y + I G + V+ + EL   +  + + 
Sbjct: 601 MAHSLLILLQLLGIVASVKKCYNNK---STTMAYIIRINGLEQVKKIGELFGKKWENYKD 657

Query: 554 LGEIGNR--KPARVKKIADFYIDVVDEVSEEEYSGYVYDLEVENEGHSFVAADGILVSNC 611
           + E   R  +P   KK  +F I  V E+ +E YSGYVY +E EN     + + GIL+ NC
Sbjct: 658 IAESYKRNIEPLGYKKSDNFAILEVKEIIKEHYSGYVYSVETENS--LLITSYGILIHNC 715

Query: 612 F 612
           F
Sbjct: 716 F 716


>dbj|BAA06142.2| (D29671) DNA-dependent DNA polymerase [Pyrococcus sp.]
            Length = 1671
            
 Score =  116 bits (289), Expect = 9e-25
 Identities = 135/534 (25%), Positives = 227/534 (42%), Gaps = 111/534 (20%)

Query: 177  EEVAKNFKFEHKVEIDGFKGEYSIPNDLYVLTFN--DGKAEWTRVTKFLRRKHEGKIRVI 234
            EE A   K E + E+    G       L V +FN    KAE  RV   +R  + GK+  I
Sbjct: 881  EENAGKVKREGETEVLEVSG-------LEVPSFNRRTNKAELKRVKALIRHDYSGKVYTI 933

Query: 235  KTKTGRTIRTTPEHKFFVYKDGELVKKRADELEPGDELVLLWRFESEETLTEINLLEAFK 294
            + K+GR I+ T  H  F  ++GELV+   DEL+PGD + +  R E  E    +NL+E   
Sbjct: 934  RLKSGRRIKITSGHSLFSVRNGELVEVTGDELKPGDLVAVPRRLELPERNHVLNLVELLL 993

Query: 295  DLPQEEKEKV-----------------------------------YVRGIKDLDLTPLKE 319
              P+EE   +                                   Y+R ++DL    LK 
Sbjct: 994  GTPEEETLDIVMTIPVKGKKNFFKGMLRTLRWIFGEEKRPRTARRYLRHLEDLGYVRLK- 1052

Query: 320  KYGDKVYYW----------------ARQDSMPLSVFYELNVDLD----------KEFRLG 353
            K G +V  W                 R +        E N   D          KE+++G
Sbjct: 1053 KIGYEVLDWDSLKNYRRLYEALVENVRYNGNKREYLVEFNSIRDAVGIMPLKELKEWKIG 1112

Query: 354  RDATTYELPSKLKITPSLAKLIGYFVSDGNYSDKDLRITVGHE------DVEKEIVNILE 407
                 + +   +++  SLAKL+GY+VS+G Y+ K      G        + + E+++ +E
Sbjct: 1113 T-LNGFRMRKLIEVDESLAKLLGYYVSEG-YARKQRNPKNGWSYSVKLYNEDPEVLDDME 1170

Query: 408  ELGLPYSFLEWEGKTKQIVIGSRLLRLVFKHVFKIPEGAPNKRLPEGFLSFPFEAKVALL 467
             L   +      G+   + I  ++  L+F+++  +   A NKR+PE   + P   ++A L
Sbjct: 1171 RLASRFFGKVRRGRN-YVEIPKKIGYLLFENMCGVL--AENKRIPEFVFTSPKGVRLAFL 1227

Query: 468  SGLFNGDGYVVRGEHHLSIGYASTSKGLIRDILYLLASLGIFA----------RVY---- 513
             G F GDG V   +    +  ++ S+ L   ++ LL S+G+ A          RVY    
Sbjct: 1228 EGYFIGDGDVHPNKR---LRLSTKSELLANQLVLLLNSVGVSAVKLGHDSGVYRVYINEE 1284

Query: 514  ----RVPKEKMKGANHDLYKLYIAGTDLVRLVELLELREGHREKLGEIGNRKPARVKKIA 569
                ++ K+K    +H + K  ++  ++   V    +      K+ E G   P + ++++
Sbjct: 1285 LPFVKLDKKKNAYYSHVIPKEVLS--EVFGKVFQKNVSPQTFRKMVEDGRLDPEKAQRLS 1342

Query: 570  -----DFYIDVVDEVSEEEYSGYVYDLEVENEGHSFVAADGILVSNCFFYAREG 618
                 D  +D V+ V  E+Y GYVYDL VE +  +F+   G++ ++  +Y   G
Sbjct: 1343 WLIEGDVVLDRVESVDVEDYDGYVYDLSVE-DNENFLVGFGLVYAHNSYYGYYG 1395


>sp|O59610|DPOL_PYRHO DNA POLYMERASE >gi|7446920|pir||C71210 probable DNA-directed DNA
           polymerase - Pyrococcus horikoshii
           >gi|3258391|dbj|BAA31074.1| (AP000007) 1235aa long
           hypothetical DNA-directed DNA polymerase [Pyrococcus
           horikoshii]
           Length = 1235
           
 Score =  112 bits (277), Expect = 2e-23
 Identities = 142/545 (26%), Positives = 228/545 (41%), Gaps = 127/545 (23%)

Query: 133 RHRSHTSLLNIVLTNRCNLNCWYCFPPTEEAVF-KFGDKVKIATFEEVAKNFKFEHKVEI 191
           R R+   L N +L +      W      E+  F K GD +     EE A+  K + + EI
Sbjct: 483 RQRAIKILANSILPDE-----WLPIVENEKVRFVKIGDFID-REIEENAERVKRDGETEI 536

Query: 192 DGFKGEYSIPNDLYVLTFN--DGKAEWTRVTKFLRRKHEGKIRVIKTKTGRTIRTTPEHK 249
              K       DL  L+FN    K+E  +V   +R ++ GK+  IK K+GR I+ T  H 
Sbjct: 537 LEVK-------DLKALSFNRETKKSELKKVKALIRHRYSGKVYSIKLKSGRRIKITSGHS 589

Query: 250 FFVYKDGELVKKRADELEPGDELVLLWRFESEETLTEINLLEAFKDLPQEEKEKVY---- 305
            F  K+G+LVK R DEL+PGD +V+  R +  E+   +NL+E    LP+EE   +     
Sbjct: 590 LFSVKNGKLVKVRGDELKPGDLVVVPGRLKLPESKQVLNLVELLLKLPEEETSNIVMMIP 649

Query: 306 VRGIKDLDLTPLKEKY-----GDKVYYWARQ--------------------DSMPLSVFY 340
           V+G K+     LK  Y     G++     R                     D   L  + 
Sbjct: 650 VKGRKNFFKGMLKTLYWIFGEGERPRTAGRYLKHLERLGYVKLKRRGCEVLDWESLKRYR 709

Query: 341 ELNVDLDKEFRLGRDATTYELP-SKLKITPSLAKL---------------IGYFVSDGNY 384
           +L   L K  +   ++  Y +  + L+   SL  +               IG F+   + 
Sbjct: 710 KLYETLIKNLKYNGNSRAYMVEFNSLRDVVSLMPIEELKEWIIGEPRGPKIGTFIDVDDS 769

Query: 385 SDKDLRITVGHEDVEKEIV-------NILEELGLPYSFLEWEGKTKQ----IVIGSRLLR 433
             K L   +   DVEK+ V       N+LE++      L   GK ++    I +  ++  
Sbjct: 770 FAKLLGYYISSGDVEKDRVKFHSKDQNVLEDIAKLAEKL--FGKVRRGRGYIEVSGKISH 827

Query: 434 LVFKHVFKIPEGAPNKRLPEGFLSFPFEAKVALLSGLFNGDGYVVRGEHHLSIGYASTSK 493
            +F+ +      A  KR+PE   + P + KVA L GL NG+           + +++ S+
Sbjct: 828 AIFRVL------AEGKRIPEFIFTSPMDIKVAFLKGL-NGNAE--------ELTFSTKSE 872

Query: 494 GLIRDILYLLASLGIFARVYRVPKEKMKGANHDLYKLYIAGTDLVRLVELLELREGHREK 553
            L+  ++ LL S+G    V  +  E  KG    +Y++YI                     
Sbjct: 873 LLVNQLILLLNSIG----VSDIKIEHEKG----VYRVYI--------------------- 903

Query: 554 LGEIGNRKPARVKKIADFYIDVVDEVSEEEYSGYVYDLEVENEGHSFVAADGILVSNCFF 613
                N+K +      D  +D V+ +  E+Y GYVYDL VE +  +F+   G+L ++  +
Sbjct: 904 -----NKKES---SNGDIVLDSVESIEVEKYEGYVYDLSVE-DNENFLVGFGLLYAHNSY 954

Query: 614 YAREG 618
           Y   G
Sbjct: 955 YGYYG 959


>pir||B70797 probable transferase - Mycobacterium tuberculosis (strain H37RV)
           >gi|2960153|emb|CAA18051.1| (AL022121) hypothetical
           protein Rv3729 [Mycobacterium tuberculosis]
           Length = 776
           
 Score =  104 bits (257), Expect = 5e-21
 Identities = 89/359 (24%), Positives = 163/359 (44%), Gaps = 47/359 (13%)

Query: 647 VQFTGGEPTLRDDLIEIIKIAKEEGYDHVQLNTDGIKLAFDPELVKKI----RQAGVNTL 702
           V F+GGEPT+   L+E +  A+      V +NT+GI+LA D   V ++    R      +
Sbjct: 142 VMFSGGEPTIHKQLLEFVDAAQARPVKTVIINTNGIRLASDRRFVDQLATRNRPGHPVHI 201

Query: 703 YLSYDGMTPQTNWK----NHWEIPLIFENVRKAGGPGIVLVPTLIRNVNDHEAGAIINFG 758
           YL +DG+   T+ +    +  ++     +   A G  + LV  + R +N+HE GA+I  G
Sbjct: 202 YLQFDGLDEATHRRIRGHDLRDVKQRALDNCAAAGLTVSLVAAVERGLNEHELGAVIRHG 261

Query: 759 LNHLDIVRGVNFQPISLVGRVPKKERQRFRITIAGAIKKIEEQTNGVISKDDWYPIPIAG 818
           +     V+ V FQP++  GR  + +    R+T +  I  I  Q        D++P+P   
Sbjct: 262 MAQPG-VQPVVFQPVTHAGRHVQFD-PLTRLTNSDIIACITAQLPEWFRPGDFFPVPCC- 318

Query: 819 HIARFFEVFTGSKYYMTSHFACGAATYVFLDREEKKVIPIPRFLDVEGFVEFLLEKA--E 876
                               +C + TY+  D E   V+PIPR L+VE +++++  +   +
Sbjct: 319 ------------------FPSCRSITYLLTDGEH--VVPIPRLLNVEDYLDYVSNRVIPD 358

Query: 877 EIEKARFKGLAKLKAI--GETVFIKFKQFYDEKNAPKGLDVLGLIKNAFVHGNYDALGKF 934
              +   + L    A+   +T+  + ++     N  +G  +             +AL   
Sbjct: 359 LAIREALENLWSASAVPGTDTMTAQLQRATAALNCAEGCGI----------NLPEALTHL 408

Query: 935 HMNTLFLGMMHFMDEYNYDVERVERCVIHYAMPDGRIVPFCTFNVIPELYRDKVQRQFS 993
                 + +  F D Y  +V+++ +C +    PDGR++PFC +N +   YR++V+ Q +
Sbjct: 409 TDRVFAIVIQDFQDPYTLNVKQLMKCCVQQITPDGRLIPFCAYNSVG--YREQVREQLT 465


>sp|Q51334|DPOL_PYRSD DNA POLYMERASE (DEEP VENT DNA POLYMERASE) [CONTAINS: PI-PSP I
            ENDONUCLEASE] >gi|2129416|pir||S68593 DNA-directed DNA
            polymerase (EC 2.7.7.7) Vent, intein containing precursor
            - Pyrococcus sp >gi|825735|gb|AAA67130.1| (U00707) Deep
            Vent DNA polymerase and PI-PspI precursor [Pyrococcus
            sp.]
            Length = 1312
            
 Score = 94.8 bits (232), Expect = 5e-18
 Identities = 115/492 (23%), Positives = 206/492 (41%), Gaps = 94/492 (19%)

Query: 213  KAEWTRVTKFLRRKHEGKIRVIKTKTGRTIRTTPEHKFFVYKDGELVKKRADELEPGDEL 272
            KA    V   +R ++ G +  I   +GR I  T  H  FVY++G+LV+   ++++ GD L
Sbjct: 553  KARVMAVKAVIRHRYSGNVYRIVLNSGRKITITEGHSLFVYRNGDLVEATGEDVKIGDLL 612

Query: 273  VLLWRFESEETLTEINLLEAFKDLPQEEKEKV---------------------------- 304
             +       E    +N++E   +L  EE E +                            
Sbjct: 613  AVPRSVNLPEKRERLNIVELLLNLSPEETEDIILTIPVKGRKNFFKGMLRTLRWIFGEEK 672

Query: 305  -------YVRGIKDLDLTPLK------------EKYG---DKVYYWARQDSMPLSVFYEL 342
                   Y+R +++L    L+            EKY    +K+    R +        E 
Sbjct: 673  RVRTASRYLRHLENLGYIRLRKIGYDIIDKEGLEKYRTLYEKLVDVVRYNGNKREYLVEF 732

Query: 343  NVDLD----------KEFRLGRDATTYELPSKLKITPSLAKLIGYFVSDGNY-----SDK 387
            N   D          KE+R+G     + + + + I    AKL+GY+VS+G+         
Sbjct: 733  NAVRDVISLMPEEELKEWRIGT-RNGFRMGTFVDIDEDFAKLLGYYVSEGSARKWKNQTG 791

Query: 388  DLRITVGHEDVEKEIVNILEELGLPYSFLEWEGKTKQIVIGSRLLRLVFKHVFKIPEGAP 447
                TV   +   E+++ +E L   +      GK   + I  ++  ++F+ +      A 
Sbjct: 792  GWSYTVRLYNENDEVLDDMEHLAKKFFGKVKRGKN-YVEIPKKMAYIIFESLCGTL--AE 848

Query: 448  NKRLPEGFLSFPFEAKVALLSGLFNGDGYVVRGEHHLSIGYASTSKGLIRDILYLLASLG 507
            NKR+PE   +     + A L G F GDG V   +    +  ++ S+ L+  ++ LL SLG
Sbjct: 849  NKRVPEVIFTSSKGVRWAFLEGYFIGDGDVHPSKR---VRLSTKSELLVNGLVLLLNSLG 905

Query: 508  IFA-------RVYRV-PKEKMKGANH----DLYKLYIAGTDLVRLV--ELLELREGHRE- 552
            + A        VYRV   E++K   +    ++Y  +I   D+++    ++ +    +++ 
Sbjct: 906  VSAIKLGYDSGVYRVYVNEELKFTEYRKKKNVYHSHIVPKDILKETFGKVFQKNISYKKF 965

Query: 553  ----KLGEIGNRKPARVKKI--ADFYIDVVDEVSEEEYSGYVYDLEVENEGHSFVAADGI 606
                + G++   K  R++ +   D  +D V E+  E Y GYVYDL V+ E  +F+A  G 
Sbjct: 966  RELVENGKLDREKAKRIEWLLNGDIVLDRVVEIKREYYDGYVYDLSVD-EDENFLAGFGF 1024

Query: 607  LVSNCFFYAREG 618
            L ++  +Y   G
Sbjct: 1025 LYAHNSYYGYYG 1036


>sp|Q58242|Y832_METJA HYPOTHETICAL PROTEIN MJ0832 >gi|2129243|pir||H64403
            ribonucleoside-triphosphate reductase (EC 1.17.4.2),
            anaerobic (intein-containing) - Methanococcus jannaschii
            >gi|1591520|gb|AAB98834.1| (U67527) anaerobic
            ribonucleoside-triphosphate reductase (nrdD)
            [Methanococcus jannaschii]
            Length = 1750
            
 Score = 88.2 bits (215), Expect = 4e-16
 Identities = 110/455 (24%), Positives = 215/455 (47%), Gaps = 52/455 (11%)

Query: 159  PTEEAVFKFGDK----VKIATFEEVAKNFKFEHKVEIDGFKGEYSIPND-LYVLTFN-DG 212
            P +E +  F +     VKI  F E   N   +  +       E  I ++ +Y  +F+ DG
Sbjct: 1061 PYDEKILIFENNEYKLVKIGEFVEKYLNRYKDRAITYGDNNIEVYIKDENIYAPSFDKDG 1120

Query: 213  KAEWTRVTKFLRRKHEGK-IRVIKTKTGRTIRTTPEHKFFVYKDG-ELVKKRADELEPGD 270
            K     +T  +R  H GK I  I+ ++G+ +R T +H  F   D  ++V+ +A +L+ GD
Sbjct: 1121 KIVLKPITHAIR--HRGKEIYEIELESGKKVRVTGDHSVFTINDNLDVVEVKASDLKVGD 1178

Query: 271  ELVLLWRFESEETLTEINLLEAFKDLPQEEKEKVYVRGIKDL------DLTPLKEKYGDK 324
             ++      + + +  I+  + +     + K+K YV+ IKD           LKE Y + 
Sbjct: 1179 FII------TPKIIPSISKDKIYLSEIVKNKDKYYVK-IKDHIKFIEEHEEILKESYKEY 1231

Query: 325  VYYWA-------RQDSMPLSVFYELNVDLDKEFRLGRDATTYELPSKLKITPSLAKLIGY 377
               W        ++++  L +  +L VD +K  ++      Y + +K+K+      LIG 
Sbjct: 1232 KTKWKDLKPVLKKKNAFRLDLIEDL-VDKEKIEKISYGHANY-INNKIKLDEKFGYLIGA 1289

Query: 378  FVSDGNYSDKDLRITVGHEDVEKEIVNILEE-LGLPYSFLEWEGKTKQ----IVIG-SRL 431
            F+S+G+++DK + I+  +++  + +V I+EE LG    ++  +G  ++     VIG ++ 
Sbjct: 1290 FLSEGHWNDKCVEISSTNKEFIENLVEIIEEILGKDAYYITVKGDKRRYKDLYVIGLNKT 1349

Query: 432  LRLVFKHVFKIPEGAPNKRLPEGFLSFPFEAKVALLSGLFNGDG--YVVRGEHHLSIGYA 489
            + ++F+ +  + + + NK +P   LS     K  L+ G  +GDG  YV   +   SI   
Sbjct: 1350 VAMIFESL-GLNKLSSNKEIPSILLSNETFLK-GLIKGYIDGDGSIYVDESKRDYSIRLY 1407

Query: 490  STSKGLIRDILYLLASLGIFARVYRVPKEKMKGANHDLYKLYIAGTDLVRLVELLELREG 549
            +TS+ L   +   L  LGI  R+    K K+     D Y + I G + +  +  +E++  
Sbjct: 1408 TTSETLRDTLCLALKILGINYRLSIDKKSKVNENWRDCYVIKITGKENIEKLLDVEIKNN 1467

Query: 550  HREKLGEIGNRKPARVKKIADFYIDVVDEVSEEEY 584
              + +          + KIA+ + +++++ S+ E+
Sbjct: 1468 GGKDV----------IPKIAEKFKEIINQYSQREW 1492


 Score = 83.1 bits (202), Expect = 1e-14
 Identities = 88/348 (25%), Positives = 147/348 (41%), Gaps = 84/348 (24%)

Query: 338 VFYELNVDLDKEFRLG--------RDATTY-----ELPSKLKITPSLAKLIGYFVSDGNY 384
           +    N   D E+R+G        R  + Y     ++P KLKIT  L + +G FV++G+Y
Sbjct: 458 IIRNFNNPYDVEYRIGDYIETNYQRTDSKYNSRQNDIPEKLKITKELCQFLGLFVAEGSY 517

Query: 385 SDKDLRITVGHEDVEKEIVN-ILEELGLPYSFLEWEGKTKQIVIGSRLLRLVFKHVFKIP 443
               + IT   +D+ K I   + E++    +   +E   +   +     R + +H   I 
Sbjct: 518 ITNGISITTKDDDIAKFIERFVKEQINENIAVKRYEDSVR--FVNKGFYRFLKEH---IN 572

Query: 444 EGAPNKRLPEGFLSFPFEAKVALLSGLFNGDGYVVRGEHHLSIGYASTSKGLIRDILYLL 503
             A NK  PE  L    E K+A L GL +GDGYV +      +   +TS+ L+  +  LL
Sbjct: 573 GKAINKNSPEFILKGDKEMKLAFLGGLISGDGYVSKDGR---VQIYTTSEQLLGQLHLLL 629

Query: 504 ASLGIFARVYRVPKEKMKGANHDL--------YKLYIA------------------GTDL 537
           + LG+   +Y + K K +G   ++        YKLY+                     + 
Sbjct: 630 SDLGM---IYSITKIKEEGEKIEIKRNEIVRNYKLYVIEIAKNCTEDLKPYVIPKYKKER 686

Query: 538 VRLVELLELREGHR---EKLGEIGNRKPAR--------------------------VKKI 568
           ++     +L   +R   E L +I ++KP                             ++I
Sbjct: 687 IKPANYDQLPYDYRIIKEHLRKITDKKPYNDYAWKSNNRKLKLNTLEKIEQLNPHLREEI 746

Query: 569 ADFYIDV---VDEVSEEEYSGYVYDLEVENEGHSFVAADGILVSNCFF 613
             F +++   + E+ E +Y+GYVYDL VE +  +F+ A GIL  N  F
Sbjct: 747 NKFKLNIPFEIKEIKEIDYNGYVYDLSVE-DNENFITATGILCHNTIF 793


>emb|CAC18555.1| (AJ245819) DNA polymerase and endonucleases [Thermococcus
            hydrothermalis]
            Length = 1668
            
 Score = 84.7 bits (206), Expect = 5e-15
 Identities = 122/493 (24%), Positives = 195/493 (38%), Gaps = 96/493 (19%)

Query: 213  KAEWTRVTKFLRRKHEGKIRVIKTKTGRTIRTTPEHKFFVYKDGELVKKRADELEPGDEL 272
            KA    V   +R ++ G +  I   +GR I  T  H  F Y DGEL +    E++ GD L
Sbjct: 519  KARVMPVKAVIRHRYSGDVYEIVLGSGRRITVTEGHSLFAYGDGELREVTGGEIKAGDLL 578

Query: 273  V------------------LLWRFESEETLTEI-------------NLLEAFKDLPQEEK 301
                               LL R   EET   I              +L   + +  EEK
Sbjct: 579  AVPRRVNLPEKKERLNLVELLRRLPEEETGDIILTIPVKGRKNFFKGMLRTLRWISGEEK 638

Query: 302  E----KVYVRGIKDLDLTPLKE---------------KYGDKVYYWARQDSMPLSVFYEL 342
                 + Y+  ++ L    LK+               K  +++    R +        E 
Sbjct: 639  RPRTARRYLEHLEGLGYVRLKKIGYEVTDREGLERYRKLYERLVEAVRYNGNKREYLVEF 698

Query: 343  NVDLD-------KEFR--LGRDATTYELPSKLKITPSLAKLIGYFVSDGNY-----SDKD 388
            N   D       +E R  L      + +   ++I    AKL+GY+VS+GN          
Sbjct: 699  NAVRDVIALMPEEELRDWLVGTRNGFRMRPFVEIEEDFAKLLGYYVSEGNARKWRNQKNG 758

Query: 389  LRITVGHEDVEKEIVNILEELGLPYSFLEWEGKTKQIVIGSRLLRLVFKHVFKIPEGAPN 448
               TV   +  + +++ +E L   +      GK   I I  ++  ++F+++      A N
Sbjct: 759  WSYTVKLYNENQRVLDDMESLAERFFGRVKRGKN-YIEIPRKMAYIIFENLCGTL--AEN 815

Query: 449  KRLPEGFLSFPFEAKVALLSGLFNGDGYVVRGEHHLSIGYASTSKGLIRDILYLLASLGI 508
            KR+PE   + P   + A + G F GDG V   +    +  ++ S+ L+  ++ LL SLG+
Sbjct: 816  KRVPEAIFTSPESVRWAFIEGYFIGDGDVHPSKR---VRLSTKSELLVNGLVLLLNSLGV 872

Query: 509  FA-------RVYRV-----------PKEKMKGANHDLYKLYIA---GTDLVRLVELLELR 547
             A        VYRV            K+K    +H + K  +    G    R V   + R
Sbjct: 873  SAIKIRHDSGVYRVYVNEELPFTDYRKKKNAYYSHVIPKEILEETFGKVFQRSVSYEKFR 932

Query: 548  EGHREKLGEIGNRKPARVKKI--ADFYIDVVDEVSEEEYSGYVYDLEVENEGHSFVAADG 605
            E    K  ++   K  R++ +   D  +D V EV +  Y GYVYDL VE E  +F+A  G
Sbjct: 933  E--LVKSEKLDGEKAKRIEWLLNGDVVLDKVLEVKKRPYEGYVYDLSVE-EDENFLAGFG 989

Query: 606  ILVSNCFFYAREG 618
            +L ++  +Y   G
Sbjct: 990  LLYAHNSYYGYYG 1002


 Score = 72.6 bits (175), Expect = 2e-11
 Identities = 69/255 (27%), Positives = 114/255 (44%), Gaps = 16/255 (6%)

Query: 367  ITPSLAKLIGYFVSDGNYSDKD--------LRITVGHEDVEKEIVNILEELGLPYSFLEW 418
            I   L +LIG  V DGN+  +         L + +  E++E++I+  L+  G+  ++ + 
Sbjct: 1184 IAVKLWELIGLLVGDGNWGGQSNWAKYNVGLSLGLDKEEIEEKILKPLKNTGIISNYYDK 1243

Query: 419  EGKTKQIVIGSRLLRLVFKHVFKIPEGAPNKRLPEGFLSFPFEAKVALLSGLFNGDGYVV 478
              K    ++   L R + ++ FK   G+  KR+PE   + P E   A L GLF+ DG V 
Sbjct: 1244 SKKGDVSILSKWLARFMVRY-FKDESGS--KRIPEFMFNLPREYIEAFLRGLFSADGTVS 1300

Query: 479  RGEHHLSIGYASTSKGLIRDILYLLASLGIFARVY-RVPKEKMKGANHDLYKLYIAGTDL 537
              +    +   S +  L   +  LL  +G+   ++      +  G     + +++   D 
Sbjct: 1301 LRKGVPEVRLTSVNPELSSSVRKLLWLVGVSNSMFVETNPNRYLGKESGTHSVHVRIKDK 1360

Query: 538  VRLVELLE-LREGHREKLGE-IGNRKPARVKKIADFYIDVVDEVSEEEYSGYVYDLEVEN 595
             R  E +  L +    KL E +G     +     DF +    +V E  Y GYVYD+EVE 
Sbjct: 1361 HRFAERIGFLLDRKATKLSENLGGHTSKKRAYKYDFDLVYPKKVEEIAYDGYVYDIEVEG 1420

Query: 596  EGHSFVAADGILVSN 610
                F  A+GILV N
Sbjct: 1421 THRFF--ANGILVHN 1433


>pir||B72665 hypothetical protein APE0745 - Aeropyrum pernix (strain K1)
           >gi|5104407|dbj|BAA79722.1| (AP000060) 726aa long
           hypothetical protein [Aeropyrum pernix]
           Length = 726
           
 Score = 84.3 bits (205), Expect = 7e-15
 Identities = 116/497 (23%), Positives = 193/497 (38%), Gaps = 69/497 (13%)

Query: 158 PPTEEAVFKFGDKVKIATFEEVAKNF-KFEHKVEIDGFKGEYSIPNDLYVLTFNDGKAEW 216
           PP E  V + GD+V++ +  E   +F + E  ++I G  G Y++  D   L     K  W
Sbjct: 178 PPWEPIVVRRGDEVRVTSIGEFVDSFLEGEGGLDIGGL-GYYTLSLDTRTL-----KPVW 231

Query: 217 TRVTKFLRRKHEGKIRVIKTKTGRTIRTTPEHKFF-VYKDGELVKKRADELEPGDELVLL 275
            R+   ++ +  G++  +K   GR+I  T  H  + + + G L    + +L PGD LV  
Sbjct: 232 RRIRGVIKHRIRGRLLRVKASKGRSIDLTGSHSIYRISRGGGLEVVGSSDLRPGDSLVTP 291

Query: 276 WRFESEETLTEINLLEAFKDLPQEEKEKVYVRGIKD-------------------LDLTP 316
              E  E+    + + A ++L     E ++V G+                     + L  
Sbjct: 292 ASVELPESAP--SSINAARELWSRGVEGIFVVGLPGEAAGYRGVERSRGYDGGHAIPLET 349

Query: 317 LKEKYGDKVYYWARQDSMPLSVFYELNVDLDKEFRLGRDATTYELPSKLKITPSLAKLIG 376
           L E+YGD V  W+      L+V                 A  + +P+ + +      L+G
Sbjct: 350 LVERYGDSV--WSLVSGAKLAVSRGA-------------AGDHPVPATIPLDTGFYLLLG 394

Query: 377 YFVSDGNYSDKDLRITV----GHEDVEKEIVNILEELGLPYSFLEWEG-KTKQIVIGSRL 431
           + VS G+   +   +TV    G E    ++V  +             G +  ++ I SR+
Sbjct: 395 FIVSAGSVDVEGGHVTVTLGPGREGYVGDVVEAVNSTAPGAGVRISSGARGMEVTIRSRV 454

Query: 432 LRLVFKHVFKIPEGAPNKRLPEGFLSFPFEAKVALLSGLFNGDGYVVRGEHHLSIGYAST 491
           L  +   VF    G PN+ +P      P   K   L GL+ G G   R     S+ YA+ 
Sbjct: 455 LSELLARVFGAGPG-PNRDIPSIVFRAPKPMKRVFLKGLYAGGGVFDRSSG--SLIYATD 511

Query: 492 SKGLIRDILYLLASLGIFARVYRVPK--------------EKMKGANHDLYKL-YIAGTD 536
           S+ L+  +  LL ++G  A  YR+                 ++      L  L +  G +
Sbjct: 512 SRSLLNGLALLLLNVG--AGGYRIDSGDSGRALALIVENAGRLDAIGEVLEHLGFHGGRE 569

Query: 537 LVRLVELLELREGHREKLGEIGNRKPARVKKIADFYIDVVDEVSEEEYSGYVYDLEVENE 596
            V+ V  LE           +  ++PA           V      E  + +VYDL VE +
Sbjct: 570 AVQGVGALERATAGLAGQATVAVQRPATRGGPGVDVAGVTGLEHLEASTEFVYDLSVEGD 629

Query: 597 GHSFVAADGILVSNCFF 613
            + F     ILV N  F
Sbjct: 630 ENFFAGLGWILVHNSAF 646


>sp|Q58815|YE20_METJA HYPOTHETICAL PROTEIN MJ1420 >gi|2127939|pir||C64477
           glutamine--fructose-6-phosphate transaminase
           (isomerizing)  (EC 2.6.1.16) (intein-containing) -
           Methanococcus jannaschii >gi|1592069|gb|AAB99430.1|
           (U67582) glucosamine--fructose-6-phosphate
           aminotransferase (isomerizing) (glmS) [Methanococcus
           jannaschii]
           Length = 1102
           
 Score = 76.9 bits (186), Expect = 1e-12
 Identities = 108/419 (25%), Positives = 184/419 (43%), Gaps = 65/419 (15%)

Query: 170 KVKIATFEEVAKNFKFEHKVEIDGFKG-EYSIPNDLYVL--------------------T 208
           K  +   EEVAK  +F   ++IDG  G  + +  D YV+                     
Sbjct: 48  KKNVGKVEEVAKKERF---LDIDGNIGIGHCLHPDTYVILPDGRMKKISEIDEDEVLSVN 104

Query: 209 FNDGKAEWTRVTKFLRRKHEGKIRVIKTKTGRT-IRTTPEHKFFVYKDGELVKKRADELE 267
           F D K    ++ KF   KH+    + K KT  + + TT EHK FV ++G++V+K   +L 
Sbjct: 105 FEDLKLYNKKIKKF---KHKAPKILYKIKTAFSELITTGEHKLFVVENGKIVEKCVKDLN 161

Query: 268 PGDELV-----LLWRFESEETLTEINLLEAFKDLPQEEKEKV-YVRGIKDLDLTPLKEKY 321
            G EL+     L + F       ++ +   +K L +  + K+  VR    L    +++  
Sbjct: 162 -GSELIGVVRKLNYSFNDNVEFKDVYVERHYK-LDETIRNKLRKVREKLGLTRKDVEKLC 219

Query: 322 GDKVYYWARQDSMPLSVFYELNV-------DLDKEFRLGRDATTYELPSKLKITPS--LA 372
           G K  Y  + ++  L    E  +        ++ E  + RD   Y  P K   TP+  L 
Sbjct: 220 GVKEIYIVKIETGKLESIEEERLKKLCSLYGINFEEIIYRDNLHYTNPVKFPKTPTPELM 279

Query: 373 KLIGYFVSDGNY-SDKDLRITVGHEDVEKEIVNILEEL-GLPYSFLEWEGKTKQIVIGSR 430
           ++IGY + DG++ S++ LR+    ++V +E   + + +  L  +  + +G    + I S+
Sbjct: 280 QIIGYIIGDGHFPSNRMLRLKDERKEVLEEYNQLFKTVFNLEGNIKKGDGNYYILEINSK 339

Query: 431 LLRLVFKHVFKIPE---GAPNKRLPEGFLSFPFEAKVALLSGLFNGDGYVVRGEHHLSIG 487
            L   F+    IPE      N+R PE       +   + L G+F+ +GY +R E    IG
Sbjct: 340 YLIDWFRE--NIPELFNKTGNERTPEFVFRLNNDLVASYLRGIFDAEGY-IRAEAK-QIG 395

Query: 488 YASTSKGLIRDILYLLASLGIFARVYRVPKEKMKGAN-----------HDLYKLYIAGT 535
              TSK  I++I +LL   GI A   ++ +++    N            +L+K YI  T
Sbjct: 396 IGMTSKCFIKEIQFLLLRFGILASYSKIKRKEENWNNTHKLLISDKKSFELFKKYIGFT 454


>pir||C71110 hypothetical protein PH0650 - Pyrococcus horikoshii
           >gi|3257058|dbj|BAA29741.1| (AP000003) 1136aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 1136
           
 Score = 76.9 bits (186), Expect = 1e-12
 Identities = 87/365 (23%), Positives = 152/365 (40%), Gaps = 56/365 (15%)

Query: 224 RRKHEG-KIRVIKTKTGRTIRTTPEHKFFVYKDGELVKKRADELEPGDELVLLWRFESEE 282
           RR  EG K+  IKT+TG  +  T  H  F + +G++V+K A  L+ GD + ++       
Sbjct: 523 RRVREGEKLIRIKTRTGNEVILTRSHPLFAFSNGDVVRKEAGNLKVGDRVAVMMNPPKPP 582

Query: 283 TLTEINLLEAFKDLPQEEKEKVYVRGIKDLDLTPLKEKYGDKVYYWARQDSMPLSVFYEL 342
               +  L  +  +     +   V   K +   P K    +K  Y    +S P+ +  E+
Sbjct: 583 QTKAVVDLSIYAKI----SDYYLVPNGKGMIKVPNKGLPPEKAQYLVSVNSHPVKLVREV 638

Query: 343 NVDLDKEFRLGRDATTYELPSKLKITPSLAKLIGYFVSDGNYSDKDLRITVGHEDVEKEI 402
           +                    KL     +    GY  S+G Y    +  T   ED  +  
Sbjct: 639 D-------------------EKLSYLAGVILGDGYISSNGYY----ISATFDDEDYMEAF 675

Query: 403 VNILEELGLPY-SFLEWEGKTKQIVIGSRLLRLVFKHVFKIPEGAPNK-RLPEGFLSFPF 460
           V+++ +    Y   ++  GK   + +GS++   +   +F IP+G   +  +P+  LS   
Sbjct: 676 VSVISDFIPNYIPNVKENGKYMVVTVGSKIFAEMLSRIFGIPKGRKLEWDVPDIVLSND- 734

Query: 461 EAKVALLSGLFNGDGYVVRGEHHLSIGYASTSKGLIRDILYLLASLGIFARVYRVPKEKM 520
           +     ++GLF+ DGYV       SI   + S+ + R I Y L  LGI + V RV  +  
Sbjct: 735 DLMRYFIAGLFDADGYVDEN----SIILVTKSENVARKIWYALQRLGIISTVSRVKNKGF 790

Query: 521 KGANHDLYKLYIAGTD----------------LVRLVELLELREGHREKLGEIGNRKPAR 564
           K    +++++ I+G D                  +L+E+L+ ++ HR   G    R P  
Sbjct: 791 K--EGEIFRVIISGVDDLAKFARSIPLHHSRKRAKLMEVLKTKKTHR---GRRAYRVPIS 845

Query: 565 VKKIA 569
            + IA
Sbjct: 846 AEMIA 850


>sp|Q58446|RPA2_METJA DNA-DIRECTED RNA POLYMERASE SUBUNIT A" >gi|2127865|pir||B64430
           DNA-directed RNA polymerase (EC 2.7.7.6) subunit A''
           (intein-containing) - Methanococcus jannaschii
           >gi|1591697|gb|AAB99047.1| (U67547) DNA-directed RNA
           polymerase, subunit A'' (rpoA2) [Methanococcus
           jannaschii]
           Length = 859
           
 Score = 76.9 bits (186), Expect = 1e-12
 Identities = 88/363 (24%), Positives = 148/363 (40%), Gaps = 68/363 (18%)

Query: 158 PPTEEAVFKFGDKVKIATF----EEVAKNFKFEHKVEIDGFKGEYSIPNDLYVLTFN-DG 212
           P  E+ + K G+ +K        +E+ + F FE K+   G      +P D+Y L+ + D 
Sbjct: 78  PYEEKIIIKEGEFIKPVEIGKLVDEMIERFGFE-KI---GNSEVCDLPIDIYALSLDQDE 133

Query: 213 KAEWTRVTKFLRRKHEGKIRVIKTKTGRTIRTTPEHKFFVYKDGELVKKRADELEPGDEL 272
           K  W R+   +R KH GK+  IKTK+GR I  TP H F + KD +++  +  EL+ GD +
Sbjct: 134 KVHWKRIISCIRHKHNGKLIKIKTKSGREITATPYHSFVIRKDNKIIPVKGSELKIGDRI 193

Query: 273 VLLWRFESEETLTEINLLEAFKDLPQEEKEKVYVRGIKDLDLTPLKEKYGDKVYYWARQD 332
            ++    +   +  IN+ +             YV G   +D   +  K   K+       
Sbjct: 194 PVVKHIPA-NCVEAINISD-------------YVSGNYVVD--NINNKIAPKI------- 230

Query: 333 SMPLSVFYELNVDLDKEFRLGRDATTYELPSKLKITPSLAKLIGYFVSDGNYSDKDLRIT 392
                                       +P+ +K+       IG ++++G+ +   + I+
Sbjct: 231 ------------------------NGKSIPNNIKLDYDFGYFIGIYLAEGSVTKYFVSIS 266

Query: 393 VGHEDVEKEIVNILEELGLPYSFLEWE-----GKTKQIVIGSRLLRLVFKHVFKIPEGAP 447
              E +  +I    ++LGL Y   E++      ++  I I S  L    + +      + 
Sbjct: 267 NVDELILNKIRAFADKLGLNYG--EYDNNNGFAESHDIRIYSSTLA---EFLSNFGTSSN 321

Query: 448 NKRLPEGFLSFPFEAKVALLSGLFNGDGYVVRGEHHLSIGYASTSKGLIRDILYLLASLG 507
            K++ E       E    L+ G F+GDG V        I   S SK LI  I  LLA   
Sbjct: 322 TKKIAEFVFGANKEFVRGLIRGYFDGDGNV--NADRKVIRVTSNSKELIDGIAILLARFN 379

Query: 508 IFA 510
           IF+
Sbjct: 380 IFS 382


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.321    0.141    0.422 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 418879563
Number of Sequences: 2977
Number of extensions: 19690237
Number of successful extensions: 47695
Number of sequences better than 1.0e-10: 19
Number of HSP's better than  0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 47589
Number of HSP's gapped (non-prelim): 48
length of query: 1042
length of database: 189,106,746
effective HSP length: 56
effective length of query: 986
effective length of database: 155,591,474
effective search space: 153413193364
effective search space used: 153413193364
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 170 (70.6 bits)