BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1899 (moaa-like) DE:MOLYBDENUM COFACTOR BIOSYNTHESIS MOAA HOMOLOG. (1042 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||H75112 molybdenum cofactor biosynthesis moaa homolog. PAB18... 2149 0.0 pir||E71020 hypothetical protein PH1458 - Pyrococcus horikoshii ... 875 0.0 gi|11499897 conserved hypothetical protein [Archaeoglobus fulgid... 469 e-131 emb|CAC11808.1| (AL445065) conserved hypothetical protein [Therm... 453 e-126 gb|AAK40578.1| Conserved hypothetical protein [Sulfolobus solfat... 398 e-109 pir||G72494 hypothetical protein APE2598 - Aeropyrum pernix (str... 395 e-108 pir||H69210 conserved hypothetical protein MTH831 - Methanobacte... 340 4e-92 sp|Q58036|Y619_METJA HYPOTHETICAL PROTEIN MJ0619 >gi|2128410|pir... 336 9e-91 sp|Q58454|YA54_METJA HYPOTHETICAL PROTEIN MJ1054 >gi|2129344|pir... 152 2e-35 dbj|BAA06142.2| (D29671) DNA-dependent DNA polymerase [Pyrococcu... 116 9e-25 sp|O59610|DPOL_PYRHO DNA POLYMERASE >gi|7446920|pir||C71210 prob... 112 2e-23 pir||B70797 probable transferase - Mycobacterium tuberculosis (s... 104 5e-21 sp|Q51334|DPOL_PYRSD DNA POLYMERASE (DEEP VENT DNA POLYMERASE) [... 95 5e-18 sp|Q58242|Y832_METJA HYPOTHETICAL PROTEIN MJ0832 >gi|2129243|pir... 88 4e-16 emb|CAC18555.1| (AJ245819) DNA polymerase and endonucleases [The... 85 5e-15 pir||B72665 hypothetical protein APE0745 - Aeropyrum pernix (str... 84 7e-15 sp|Q58815|YE20_METJA HYPOTHETICAL PROTEIN MJ1420 >gi|2127939|pir... 77 1e-12 pir||C71110 hypothetical protein PH0650 - Pyrococcus horikoshii ... 77 1e-12 sp|Q58446|RPA2_METJA DNA-DIRECTED RNA POLYMERASE SUBUNIT A" >gi|... 77 1e-12 >pir||H75112 molybdenum cofactor biosynthesis moaa homolog. PAB1899 - Pyrococcus abyssi (strain Orsay) >gi|5458128|emb|CAB49617.1| (AJ248285) MOLYBDENUM COFACTOR BIOSYNTHESIS MOAA HOMOLOG. [Pyrococcus abyssi] Length = 1042 Score = 2149 bits (5508), Expect = 0.0 Identities = 1042/1042 (100%), Positives = 1042/1042 (100%) Query: 1 MAETVGEIPSGEKEFEASTKRLREIIEFPELSEDEFHELLKSASRGYGSPLPHRTYSLCP 60 MAETVGEIPSGEKEFEASTKRLREIIEFPELSEDEFHELLKSASRGYGSPLPHRTYSLCP Sbjct: 1 MAETVGEIPSGEKEFEASTKRLREIIEFPELSEDEFHELLKSASRGYGSPLPHRTYSLCP 60 Query: 61 ETRRVVPAVVWEKDGKVWITKKCPEGMITDLYYEDVELYYRFSRWKFEEKKLFSVNVENT 120 ETRRVVPAVVWEKDGKVWITKKCPEGMITDLYYEDVELYYRFSRWKFEEKKLFSVNVENT Sbjct: 61 ETRRVVPAVVWEKDGKVWITKKCPEGMITDLYYEDVELYYRFSRWKFEEKKLFSVNVENT 120 Query: 121 GVNCPFDCGLCARHRSHTSLLNIVLTNRCNLNCWYCFPPTEEAVFKFGDKVKIATFEEVA 180 GVNCPFDCGLCARHRSHTSLLNIVLTNRCNLNCWYCFPPTEEAVFKFGDKVKIATFEEVA Sbjct: 121 GVNCPFDCGLCARHRSHTSLLNIVLTNRCNLNCWYCFPPTEEAVFKFGDKVKIATFEEVA 180 Query: 181 KNFKFEHKVEIDGFKGEYSIPNDLYVLTFNDGKAEWTRVTKFLRRKHEGKIRVIKTKTGR 240 KNFKFEHKVEIDGFKGEYSIPNDLYVLTFNDGKAEWTRVTKFLRRKHEGKIRVIKTKTGR Sbjct: 181 KNFKFEHKVEIDGFKGEYSIPNDLYVLTFNDGKAEWTRVTKFLRRKHEGKIRVIKTKTGR 240 Query: 241 TIRTTPEHKFFVYKDGELVKKRADELEPGDELVLLWRFESEETLTEINLLEAFKDLPQEE 300 TIRTTPEHKFFVYKDGELVKKRADELEPGDELVLLWRFESEETLTEINLLEAFKDLPQEE Sbjct: 241 TIRTTPEHKFFVYKDGELVKKRADELEPGDELVLLWRFESEETLTEINLLEAFKDLPQEE 300 Query: 301 KEKVYVRGIKDLDLTPLKEKYGDKVYYWARQDSMPLSVFYELNVDLDKEFRLGRDATTYE 360 KEKVYVRGIKDLDLTPLKEKYGDKVYYWARQDSMPLSVFYELNVDLDKEFRLGRDATTYE Sbjct: 301 KEKVYVRGIKDLDLTPLKEKYGDKVYYWARQDSMPLSVFYELNVDLDKEFRLGRDATTYE 360 Query: 361 LPSKLKITPSLAKLIGYFVSDGNYSDKDLRITVGHEDVEKEIVNILEELGLPYSFLEWEG 420 LPSKLKITPSLAKLIGYFVSDGNYSDKDLRITVGHEDVEKEIVNILEELGLPYSFLEWEG Sbjct: 361 LPSKLKITPSLAKLIGYFVSDGNYSDKDLRITVGHEDVEKEIVNILEELGLPYSFLEWEG 420 Query: 421 KTKQIVIGSRLLRLVFKHVFKIPEGAPNKRLPEGFLSFPFEAKVALLSGLFNGDGYVVRG 480 KTKQIVIGSRLLRLVFKHVFKIPEGAPNKRLPEGFLSFPFEAKVALLSGLFNGDGYVVRG Sbjct: 421 KTKQIVIGSRLLRLVFKHVFKIPEGAPNKRLPEGFLSFPFEAKVALLSGLFNGDGYVVRG 480 Query: 481 EHHLSIGYASTSKGLIRDILYLLASLGIFARVYRVPKEKMKGANHDLYKLYIAGTDLVRL 540 EHHLSIGYASTSKGLIRDILYLLASLGIFARVYRVPKEKMKGANHDLYKLYIAGTDLVRL Sbjct: 481 EHHLSIGYASTSKGLIRDILYLLASLGIFARVYRVPKEKMKGANHDLYKLYIAGTDLVRL 540 Query: 541 VELLELREGHREKLGEIGNRKPARVKKIADFYIDVVDEVSEEEYSGYVYDLEVENEGHSF 600 VELLELREGHREKLGEIGNRKPARVKKIADFYIDVVDEVSEEEYSGYVYDLEVENEGHSF Sbjct: 541 VELLELREGHREKLGEIGNRKPARVKKIADFYIDVVDEVSEEEYSGYVYDLEVENEGHSF 600 Query: 601 VAADGILVSNCFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDL 660 VAADGILVSNCFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDL Sbjct: 601 VAADGILVSNCFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDL 660 Query: 661 IEIIKIAKEEGYDHVQLNTDGIKLAFDPELVKKIRQAGVNTLYLSYDGMTPQTNWKNHWE 720 IEIIKIAKEEGYDHVQLNTDGIKLAFDPELVKKIRQAGVNTLYLSYDGMTPQTNWKNHWE Sbjct: 661 IEIIKIAKEEGYDHVQLNTDGIKLAFDPELVKKIRQAGVNTLYLSYDGMTPQTNWKNHWE 720 Query: 721 IPLIFENVRKAGGPGIVLVPTLIRNVNDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVP 780 IPLIFENVRKAGGPGIVLVPTLIRNVNDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVP Sbjct: 721 IPLIFENVRKAGGPGIVLVPTLIRNVNDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVP 780 Query: 781 KKERQRFRITIAGAIKKIEEQTNGVISKDDWYPIPIAGHIARFFEVFTGSKYYMTSHFAC 840 KKERQRFRITIAGAIKKIEEQTNGVISKDDWYPIPIAGHIARFFEVFTGSKYYMTSHFAC Sbjct: 781 KKERQRFRITIAGAIKKIEEQTNGVISKDDWYPIPIAGHIARFFEVFTGSKYYMTSHFAC 840 Query: 841 GAATYVFLDREEKKVIPIPRFLDVEGFVEFLLEKAEEIEKARFKGLAKLKAIGETVFIKF 900 GAATYVFLDREEKKVIPIPRFLDVEGFVEFLLEKAEEIEKARFKGLAKLKAIGETVFIKF Sbjct: 841 GAATYVFLDREEKKVIPIPRFLDVEGFVEFLLEKAEEIEKARFKGLAKLKAIGETVFIKF 900 Query: 901 KQFYDEKNAPKGLDVLGLIKNAFVHGNYDALGKFHMNTLFLGMMHFMDEYNYDVERVERC 960 KQFYDEKNAPKGLDVLGLIKNAFVHGNYDALGKFHMNTLFLGMMHFMDEYNYDVERVERC Sbjct: 901 KQFYDEKNAPKGLDVLGLIKNAFVHGNYDALGKFHMNTLFLGMMHFMDEYNYDVERVERC 960 Query: 961 VIHYAMPDGRIVPFCTFNVIPELYRDKVQRQFSYSWEEWKKLHPDWDYMKDKYVRTKEFV 1020 VIHYAMPDGRIVPFCTFNVIPELYRDKVQRQFSYSWEEWKKLHPDWDYMKDKYVRTKEFV Sbjct: 961 VIHYAMPDGRIVPFCTFNVIPELYRDKVQRQFSYSWEEWKKLHPDWDYMKDKYVRTKEFV 1020 Query: 1021 EKMKKSELYRKTYIDIVNYFER 1042 EKMKKSELYRKTYIDIVNYFER Sbjct: 1021 EKMKKSELYRKTYIDIVNYFER 1042 >pir||E71020 hypothetical protein PH1458 - Pyrococcus horikoshii >gi|3257882|dbj|BAA30565.1| (AP000006) 587aa long hypothetical protein [Pyrococcus horikoshii] Length = 587 Score = 875 bits (2237), Expect = 0.0 Identities = 410/432 (94%), Positives = 427/432 (97%) Query: 611 CFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDLIEIIKIAKEE 670 CFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDLIEIIKIAKEE Sbjct: 156 CFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDLIEIIKIAKEE 215 Query: 671 GYDHVQLNTDGIKLAFDPELVKKIRQAGVNTLYLSYDGMTPQTNWKNHWEIPLIFENVRK 730 GYDH+QLNTDGIKLAFDPELVKK+R+AGVNTLYLSYDGMTPQTNWKNHWEIPLIFENVRK Sbjct: 216 GYDHIQLNTDGIKLAFDPELVKKLREAGVNTLYLSYDGMTPQTNWKNHWEIPLIFENVRK 275 Query: 731 AGGPGIVLVPTLIRNVNDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVPKKERQRFRIT 790 AGGPGIVLVPTLIRN+NDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVP+KERQRFRIT Sbjct: 276 AGGPGIVLVPTLIRNINDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVPRKERQRFRIT 335 Query: 791 IAGAIKKIEEQTNGVISKDDWYPIPIAGHIARFFEVFTGSKYYMTSHFACGAATYVFLDR 850 IAGAIKKIEEQTNGVI+K+DWYPIPIAGHIARFFE FTG KYYMTSHFACGAATYVFLDR Sbjct: 336 IAGAIKKIEEQTNGVIAKEDWYPIPIAGHIARFFEAFTGRKYYMTSHFACGAATYVFLDR 395 Query: 851 EEKKVIPIPRFLDVEGFVEFLLEKAEEIEKARFKGLAKLKAIGETVFIKFKQFYDEKNAP 910 EEKKVIPIPRF+DV+GFVEFL+EKAEEIEKARFK LAKLKAIGET+F+KFKQFYDEKNAP Sbjct: 396 EEKKVIPIPRFIDVDGFVEFLVEKAEEIEKARFKSLAKLKAIGETIFVKFKQFYDEKNAP 455 Query: 911 KGLDVLGLIKNAFVHGNYDALGKFHMNTLFLGMMHFMDEYNYDVERVERCVIHYAMPDGR 970 KGLDVLGLIKNAFVHG YDALGKFHMNTLF+GMMHFMDEYNYDVERVERCVIHYAMPDGR Sbjct: 456 KGLDVLGLIKNAFVHGTYDALGKFHMNTLFIGMMHFMDEYNYDVERVERCVIHYAMPDGR 515 Query: 971 IVPFCTFNVIPELYRDKVQRQFSYSWEEWKKLHPDWDYMKDKYVRTKEFVEKMKKSELYR 1030 IVPFCTFNVIPE+YRDKVQRQFSYSWEEWKKLHPDWDY KDKY+RTKEFVEKMKKSE+Y+ Sbjct: 516 IVPFCTFNVIPEIYRDKVQRQFSYSWEEWKKLHPDWDYKKDKYIRTKEFVEKMKKSEVYK 575 Query: 1031 KTYIDIVNYFER 1042 KTYIDIVNYFER Sbjct: 576 KTYIDIVNYFER 587 Score = 319 bits (810), Expect = 8e-86 Identities = 150/210 (71%), Positives = 176/210 (83%), Gaps = 11/210 (5%) Query: 1 MAETVGEIPSGEKEFEASTKRLREIIEFPELSEDEFHELLKSASRGYGSPLPHRTYSLCP 60 MAET+GE+PSGEKEFEASTK +REIIEFPE++E+EF++LLKSAS+GYGSPLPHRTYSLCP Sbjct: 1 MAETLGEVPSGEKEFEASTKHVREIIEFPEMTEEEFNKLLKSASKGYGSPLPHRTYSLCP 60 Query: 61 ETRRVVPAVVWEKDGKVWITKKCPEGMITDLYYEDVELYYRFSRWKFEEKKLFSVNVENT 120 E+RRVVPAVVWEKDGKVWITKKCPEGMITDLYYEDVELYYRFS+W+FEEKKLFS NV NT Sbjct: 61 ESRRVVPAVVWEKDGKVWITKKCPEGMITDLYYEDVELYYRFSKWRFEEKKLFSANVSNT 120 Query: 121 GVNCPFDCGLCARHRSHTSLLNIVLTNRCNLNCWYCFPPTEEAVFKFGDKVKIATFEEV- 179 G+NCPFDCGLC RHRSHTSL+NIVLTNRCNL+CWYCF E G+ + T E++ Sbjct: 121 GINCPFDCGLCPRHRSHTSLINIVLTNRCNLSCWYCFFYARE-----GEPIYEPTLEQIR 175 Query: 180 --AKNFKFEHKVEIDGFK---GEYSIPNDL 204 +N K EH + + + GE ++ +DL Sbjct: 176 MMLRNAKKEHPIGANAVQFTGGEPTLRDDL 205 >gi|11499897 conserved hypothetical protein [Archaeoglobus fulgidus] >gi|7451255|pir||D69539 conserved hypothetical protein AF2316 - Archaeoglobus fulgidus >gi|2648203|gb|AAB88940.1| (AE000944) conserved hypothetical protein [Archaeoglobus fulgidus] Length = 518 Score = 469 bits (1194), Expect = e-131 Identities = 226/392 (57%), Positives = 289/392 (73%), Gaps = 9/392 (2%) Query: 611 CFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDLIEIIKIAKEE 670 CFFYAR +YEPT+EQIR M+R AK PIG NAVQ TGGEPTLRDDLI+II++ KEE Sbjct: 117 CFFYARRAGYVYEPTIEQIREMVRKAKNMKPIGCNAVQLTGGEPTLRDDLIDIIRMIKEE 176 Query: 671 GYDHVQLNTDGIKLAFDPELVKKIRQAGVNTLYLSYDGMTPQTNWKNHWEIPLIFENVRK 730 GYDH+QLNT+GI+LA DP+ ++R AGVNT+YLS+DG+ +TN KNH EIP I EN R+ Sbjct: 177 GYDHIQLNTNGIRLAEDPDFALRVRVAGVNTVYLSFDGVDEKTNPKNHHEIPKILENCRR 236 Query: 731 AGGPGIVLVPTLIRNVNDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVPKKERQRFRIT 790 A G+VLVPT+I+ VNDH+ G II F ++DIVRGVNFQP+SLVG +P+KER++FRIT Sbjct: 237 A-QLGLVLVPTVIKGVNDHQLGDIIRFAAENIDIVRGVNFQPVSLVGSMPRKEREQFRIT 295 Query: 791 IAGAIKKIEEQTNGVISKDDWYPIPIAGHIARFFEVFTGS-KYYMTSHFACGAATYVFLD 849 I IK IEEQTNG I ++D+YP+P I+RF E TG +Y +T+HFACG ATY+F Sbjct: 296 IPDCIKAIEEQTNGEIGREDFYPVPSVVPISRFVEALTGQPQYELTTHFACGMATYIF-- 353 Query: 850 REEKKVIPIPRFLDVEGFVEFLLEKAEEIEKARFKGLAKLKAIGETVFIKFKQFYDEKNA 909 ++ ++IPI RF+DVEG EFL EKAEEI K+R K + +K I I ++F D A Sbjct: 354 KDNGRLIPITRFVDVEGLFEFLNEKAEEIAKSRMKTIRAIKDI-----IDLRKFVDTSKA 408 Query: 910 PKGLDVLGLIKNAFVHGNYDALGKFHMNTLFLGMMHFMDEYNYDVERVERCVIHYAMPDG 969 PKG ++ ++ + +Y LG+FH+ +LF+GMMHF D YNYD+ RVERC IHY PDG Sbjct: 409 PKGFNIAKILYEVLIKHDYSTLGEFHVKSLFIGMMHFQDLYNYDIARVERCEIHYGSPDG 468 Query: 970 RIVPFCTFNVIPELYRDKVQRQFSYSWEEWKK 1001 RI+PFCTFNVIPE YRD + ++ EEW+K Sbjct: 469 RIIPFCTFNVIPERYRDAIHEKYGIPIEEWEK 500 Score = 117 bits (290), Expect = 7e-25 Identities = 59/136 (43%), Positives = 85/136 (62%), Gaps = 4/136 (2%) Query: 51 LPHRTYSLCPETRRVVPAVVWEKDGKVWITKKCPE-GMITDLYYEDVELYYRFSRWKFEE 109 LP++T SLCPE +++ A V+E++GKV I K C E G D+Y+ D E++ + +R+ + Sbjct: 13 LPYKTKSLCPECLKILEAEVYEENGKVMIRKVCEEHGEFVDVYWGDAEMFKKAARFAADG 72 Query: 110 KKLFSVNVENTGVNCPFDCGLCARHRSHTSLLNIVLTNRCNLNCWYCFPPTEEAVFKFGD 169 + + +NT CPF CGLC H+SHT+LLNIVLTNRC+L CWYCF A + + Sbjct: 73 HGISTPITQNT--TCPFSCGLCNNHKSHTALLNIVLTNRCDLACWYCFFYARRAGYVYEP 130 Query: 170 KV-KIATFEEVAKNFK 184 + +I AKN K Sbjct: 131 TIEQIREMVRKAKNMK 146 >emb|CAC11808.1| (AL445065) conserved hypothetical protein [Thermoplasma acidophilum] Length = 571 Score = 453 bits (1153), Expect = e-126 Identities = 215/423 (50%), Positives = 299/423 (69%), Gaps = 6/423 (1%) Query: 611 CFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDLIEIIKIAKEE 670 CFFYA+E EPIYEPT +QIRMMLR K E P+GANAVQ TGGEPT+RDD+I+I++IA+EE Sbjct: 126 CFFYAKENEPIYEPTQDQIRMMLRRMKNEKPVGANAVQITGGEPTMRDDIIDIVRIAREE 185 Query: 671 GYDHVQLNTDGIKLAFDPELVKKIRQAGVNTLYLSYDGMTPQTNWKNHWEIPLIFENVRK 730 GYDHVQLNT+ ++ AFDP+ V+++R+AG N +Y S+DG TP++N KN WEIP EN +K Sbjct: 186 GYDHVQLNTNSVRAAFDPDFVRRVREAGSNVIYTSFDGPTPRSNPKNFWEIPAALENYKK 245 Query: 731 AGGPGIVLVPTLIRNVNDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVPKKERQRFRIT 790 A G+VLVPT+I VND G II FGL+++D+VR VNFQP+SLVGR+P + R + RIT Sbjct: 246 A-PLGVVLVPTVIGGVNDMYLGDIIRFGLSNIDVVRAVNFQPVSLVGRMPDRARAKQRIT 304 Query: 791 IAGAIKKIEEQTNGVISKDDWYPIPIAGHIARFFEVFTGSKYYMTS-HFACGAATYVFLD 849 I GAIKKIE+QT+G+I ++D++ +P ++ F G Y S H+ACG TY+F Sbjct: 305 IPGAIKKIEQQTDGLIGREDFFTVPSTASVSNFVAALKGRPTYKLSIHYACGMGTYLF-- 362 Query: 850 REEKKVIPIPRFLDVEGFVEFLLEKAEEIEKARFKGLAKLKAIGETVFIKFKQFYDEKNA 909 ++++KVIP+ RF+DV+G E++ A+EI + FK L K+++ + ++ K+F D + A Sbjct: 363 KDDEKVIPVTRFVDVKGMFEYIQNLADEIGDSTFKSLRKVESTAKLLY-NLKKFVDYEKA 421 Query: 910 PKGLDVLGLIKNAFVHGNYDALGKFHMNTLFLGMMHFMDEYNYDVERVERCVIHYAMPDG 969 PK + ++ NAF G+Y L FH ++F+G MHF D Y YDV+RVERC IHYAMPDG Sbjct: 422 PKDFKLKDMVYNAFTEGDYHGLKAFHYKSMFIGFMHFQDPYTYDVDRVERCDIHYAMPDG 481 Query: 970 RIVPFCTFNVIPELYRDKVQRQFSYSWEEWKKLHPDWDYMKDKYVRTKEFVEKMKKSELY 1029 R++PFC FNVIPELYRD QR++S + +++ K+KY R +K + Y Sbjct: 482 RVIPFCAFNVIPELYRDSTQRKYSIPAKVYEE-KTGRSLKKEKYFREYSLEDKKRIIAFY 540 Query: 1030 RKT 1032 ++ Sbjct: 541 ERS 543 Score = 101 bits (249), Expect = 5e-20 Identities = 48/113 (42%), Positives = 72/113 (63%), Gaps = 10/113 (8%) Query: 55 TYSLCPET-------RRVVPAVVWEKDGKVWITKKCPE-GMITDLYYEDVELYYRFSRWK 106 T SLCP + +PA+V+E+ G+V + K+CPE G+ + Y+ED E++ +W+ Sbjct: 15 TESLCPGCVDEEKFDQMRIPAIVYEEGGEVKLIKECPEHGVTVEKYWEDYEMFEEAKKWQ 74 Query: 107 FEEKKLFSVNVEN--TGVNCPFDCGLCARHRSHTSLLNIVLTNRCNLNCWYCF 157 K+ + NV + + CP CGLC +H+SHT L NIV+TNRC+L+CWYCF Sbjct: 75 DPGVKILNPNVAYYASKIVCPTHCGLCVKHKSHTGLGNIVVTNRCDLSCWYCF 127 >gb|AAK40578.1| Conserved hypothetical protein [Sulfolobus solfataricus] Length = 582 Score = 398 bits (1012), Expect = e-109 Identities = 201/434 (46%), Positives = 283/434 (64%), Gaps = 20/434 (4%) Query: 611 CFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDLIEIIKIAKEE 670 CFFYA + +YEPTLEQI+ M+ KK+ +Q TGGEPTLR+D+IEIIK+ +E Sbjct: 152 CFFYAEKAGYVYEPTLEQIKFMVDQLKKQDI--TLVIQVTGGEPTLREDIIEIIKMLREN 209 Query: 671 GYDHVQLNTDGIKLAF----DPELVKK----IRQAGVNTLYLSYDGMTPQTNWKNHWEIP 722 G H+QLN+ G A DP+ K +R+AGVNT+Y+S+DG T +TN KNHWEIP Sbjct: 210 GVKHIQLNSWGGTFAKLYLEDPDKAIKYARALREAGVNTVYMSFDGTTRKTNPKNHWEIP 269 Query: 723 LIFENVRKAGGPGIVLVPTLIRNVNDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVPKK 782 E R+AG +VLVPT+I+ VND++ G I+ F ++D+VR VNFQP+SL G + + Sbjct: 270 YTLEVFRRAGMTSVVLVPTVIKTVNDNDLGNIVKFAAYNMDVVRSVNFQPVSLTGMMKRN 329 Query: 783 ERQRFRITIAGAIKKIEEQTNGVISKDDWYPIPIAGHIARFFEVFTGSKYY-MTSHFACG 841 R +FRITI IK IEEQT+G I+KD WYPI + +R E TG + + M +H +CG Sbjct: 330 MRAKFRITIPEVIKNIEEQTDGEITKDSWYPIGTSVVFSRLVEALTGKEQFEMANHPSCG 389 Query: 842 AATYVFLD--REEKKVIPIPRFLDVEGFVEFLLEKAEEIEKARFKGLAKLKAIGETVFIK 899 A TYV+++ E IPI +F+D+EG +E+L EK EE+ + A + V Sbjct: 390 AGTYVYVEWRNHEPHFIPISKFIDLEGLLEYLKEKEEELREG-----ANKVWVASKVLYS 444 Query: 900 FKQFYDEKNAPKGLDVLGLIKNAFVHGNYDALGKFHMNTLFLGMMHFMDEYNYDVERVER 959 ++F D++ PK DV ++ N +H NY+ALG++H TLFLG MHFMD YNYDV+RV R Sbjct: 445 IRKFIDKEQGPKDFDVYKMLYNIIIHHNYEALGEWHYRTLFLGSMHFMDLYNYDVQRVMR 504 Query: 960 CVIHYAMPDGRIVPFCTFNVIPELYRDKVQRQFSYSWEEWKKLHPDWDYMKDKYVRTKEF 1019 C IHY +PDGR++PFCT+NV+ +LYRDKV R++ ++W K H + + + D ++ K Sbjct: 505 CDIHYVVPDGRVIPFCTYNVLNDLYRDKVLREYQIPLDKWTKEHGE-NSLGDA-IKYKRI 562 Query: 1020 VEKMKKSELYRKTY 1033 ++ SE+Y+ TY Sbjct: 563 ASTLENSEIYKNTY 576 Score = 123 bits (306), Expect = 9e-27 Identities = 59/132 (44%), Positives = 87/132 (65%), Gaps = 15/132 (11%) Query: 48 GSPLP---------HRTYSLCPETRRVVPAVVWEKDGKVWITKKCPE-GMITDLYYEDVE 97 G PLP T+SLCP R++PA ++EK+GK++I K CPE G DLYY D Sbjct: 35 GGPLPTLAKDEKLVRVTHSLCPACYRLLPATIFEKEGKLFIRKICPEHGEFEDLYYADSS 94 Query: 98 LYYRFSRWKFEEK--KLFSVNVENTGVNCPFDCGLCARHRSHTSLLNIVLTNRCNLNCWY 155 LYY+F W++E K K+ V++++ CP++CGLC H H++L+N+V+TNRC+L+CWY Sbjct: 95 LYYKFDYWEYEGKGPKVPYVDLKSP---CPYNCGLCPMHHQHSALVNLVITNRCDLSCWY 151 Query: 156 CFPPTEEAVFKF 167 CF E+A + + Sbjct: 152 CFFYAEKAGYVY 163 >pir||G72494 hypothetical protein APE2598 - Aeropyrum pernix (strain K1) >gi|5106304|dbj|BAA81615.1| (AP000064) 610aa long hypothetical protein [Aeropyrum pernix] Length = 610 Score = 395 bits (1004), Expect = e-108 Identities = 206/469 (43%), Positives = 307/469 (64%), Gaps = 35/469 (7%) Query: 595 NEGHSFVAADGILVSN--------CFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANA 646 +E HS A I+V+N CFFYA IYEP++EQI+ M+R ++ G++ Sbjct: 137 HENHS--ALVNIVVTNRCDLSCFYCFFYAERAGYIYEPSIEQIKFMVRQVARQRQ-GSDV 193 Query: 647 ---VQFTGGEPTLRDDLIEIIKIAKEEGYDHVQLNTDGIKLAF----DP----ELVKKIR 695 +Q TGGEPT+R+DL++++K +E G ++QLNT+GI +A +P + V+ +R Sbjct: 194 HVNIQITGGEPTVREDLVDVVKAIREAGAHYIQLNTNGINVARRYLDNPPGAIDYVRSLR 253 Query: 696 QAGVNTLYLSYDGMTPQTNWKNHWEIPLIFENVRKAGGPGIVLVPTLIRNVNDHEAGAII 755 +AGV+ +Y+S+DG+TP+ NWKNH+E P + ++ G +VLVPT+IR +NDHE G II Sbjct: 254 EAGVSVVYMSFDGVTPKVNWKNHYEAPFALKAFQEGGLDNVVLVPTVIRTINDHEVGDII 313 Query: 756 NFGLNHLDIVRGVNFQPISLVGRVPKKERQRFRITIAGAIKKIEEQTNGVISKDDWYPIP 815 F H+D+VRGVNFQP+SL G + K ER+R RITI IK+IEEQT+G I D WYP+P Sbjct: 314 RFAGKHIDVVRGVNFQPVSLTGMMRKHERERMRITIPDVIKRIEEQTDGQIPMDAWYPVP 373 Query: 816 IAGHIARFFEVFTGSKY-YMTSHFACGAATYVF-LDREE----KKVIPIPRFLDVEGFVE 869 + + + TG Y +++H ACG+ATYVF L+R+ ++ +PI +DVEGF+E Sbjct: 374 VVAKFVKAIDALTGKLYDTLSNHPACGSATYVFALERDRYGVPRRFLPITEVIDVEGFIE 433 Query: 870 FLLEKAEEIEKARFKGLAKLKAIGETVFIKFKQFYDEKNAPKGLDVLGLIKNAFVHGNYD 929 FL E+ ++E + L++LK E V+ + ++F D P+ LD+ LI + F+ NY+ Sbjct: 434 FLDEERIKLEHNSGR-LSRLKVAAEIVW-RARRFVDFDRMPRDLDIYKLIVSIFLRKNYE 491 Query: 930 ALGKFHMNTLFLGMMHFMDEYNYDVERVERCVIHYAMPDGRIVPFCTFNVIPELYRDKVQ 989 A+ FH TLFLGMMHFMD YNYD+ RV RC IHYA+PDGR+VPFC FNV+ ++YRD VQ Sbjct: 492 AIKTFHKKTLFLGMMHFMDRYNYDITRVRRCNIHYALPDGRLVPFCAFNVLEDIYRDNVQ 551 Query: 990 RQFSYSWEEWKKLHPDWDYMKDKYVRTKEFVEKMKKSELYRKTYIDIVN 1038 ++F+ + K L +KY R + +++++ +S +YR+ Y I++ Sbjct: 552 KRFAKA----KNLRIKGFNPGEKYDR-RRYIKRILESPIYREAYRGIID 595 Score = 108 bits (268), Expect = 3e-22 Identities = 64/173 (36%), Positives = 95/173 (53%), Gaps = 14/173 (8%) Query: 46 GYGSPLP---------HRTYSLCPETRRVVPAVVWEKDGKVWITKKCPE-GMITDLYYED 95 G G PLP T S+CP R++PAV+ + G+++I KKCPE G I DLYY D Sbjct: 38 GVGGPLPAVREGERLIRYTGSICPYCLRLLPAVIVARGGRLYIRKKCPEHGEIEDLYYGD 97 Query: 96 VELYYRFSRWKFEEKKLFSVNVENTGVN-CPFDCGLCARHRSHTSLLNIVLTNRCNLNCW 154 Y+R +W+ L T CP+ CGLC+ H +H++L+NIV+TNRC+L+C+ Sbjct: 98 ERFYWRQMKWEETGLGLSGAGPYTTATAPCPYACGLCSLHENHSALVNIVVTNRCDLSCF 157 Query: 155 YCFPPTEEAVFKFGDKVKIATF--EEVAKNFK-FEHKVEIDGFKGEYSIPNDL 204 YCF E A + + ++ F +VA+ + + V I GE ++ DL Sbjct: 158 YCFFYAERAGYIYEPSIEQIKFMVRQVARQRQGSDVHVNIQITGGEPTVREDL 210 >pir||H69210 conserved hypothetical protein MTH831 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621921|gb|AAB85329.1| (AE000860) molybdenum cofactor biosynthesis MoaA homolog [Methanobacterium thermoautotrophicum] Length = 497 Score = 340 bits (864), Expect = 4e-92 Identities = 179/396 (45%), Positives = 253/396 (63%), Gaps = 15/396 (3%) Query: 611 CFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDLIEIIKIAKEE 670 CF A IYEPT E+IR MLRN ++ P+ A+Q+ GGEPT+R D+++++K+A+EE Sbjct: 110 CFANAAVSNYIYEPTYEEIREMLRNLRRNRPVPTPAIQYAGGEPTVRKDIVDLVKLAREE 169 Query: 671 GYDHVQLNTDGIKLAFDPELVKKIRQAGVNTLYLSYDGMTPQ----TNWKNHWEIPL-IF 725 G+ HVQ+ T+G++LA PEL ++R+AG+NT+YL +DG+T + + KN I L Sbjct: 170 GFTHVQIATNGVRLARKPELAAELREAGLNTVYLQFDGVTEEPYITSRGKNLLPIKLQAI 229 Query: 726 ENVRKAGGPGIVLVPTLIRNVNDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVPKKERQ 785 EN RK G GIVLVPTL+R +ND++ G II F ++++DI+RGVNFQP+S GR P + Sbjct: 230 ENCRKV-GLGIVLVPTLVRGLNDNQVGDIIRFAIDNIDIIRGVNFQPVSFAGRTPADRVE 288 Query: 786 RFRITIAGAIKKIEEQTNGVISKDDWYPIPIAGHIARFFEVFTGS-KYYMTSHFACGAAT 844 RITI K +E QT IS DD+YP I+ F G + T H CG AT Sbjct: 289 EQRITIPDFQKLVEAQTGSEISMDDFYPASSVRPISDFVAAIEGEPQVTFTCHQHCGTAT 348 Query: 845 YVFLDREEKKVIPIPRFLDVEGFVEFLLEKAEEIEKARFKGLAKLKAIGETVFIKFKQFY 904 Y+FL E+ K+IPI RF+DV+ F E L + +EIE+ AK + I + I+ + Sbjct: 349 YIFL--EDDKIIPITRFIDVDRFFEVLEKGKDEIEEGGI--AAKARVIARSA-IELPKTL 403 Query: 905 DEKNAPKGLDVLGLIKNAFVHGNYDALGKFHMNTLFLGMMHFMDEYNYDVERVERCVIHY 964 D+ AP+ +D+ ++ + F +Y ALG+FH NTL + MHFMD +N+D++RV RCVIHY Sbjct: 404 DKSEAPESVDIKRILTSIFKERSYTALGEFHYNTLLISCMHFMDPWNFDIDRVRRCVIHY 463 Query: 965 AMPDGRIVPFCTFNVIPELYRDKVQRQFSYSWEEWK 1000 A+PDGRIVPFCT N ++R V+R F+ E K Sbjct: 464 ALPDGRIVPFCTMN---SIHRADVERHFAKPLNESK 496 Score = 88.9 bits (217), Expect = 3e-16 Identities = 45/105 (42%), Positives = 63/105 (59%), Gaps = 2/105 (1%) Query: 54 RTYSLCPETRRVVPAVVWEKDGKVWITKKCPE-GMITDLYYEDVELYYRFSRWKFEEKKL 112 +T SLCPE R V A V+E +G+V I K+CPE G ++Y+ + ++Y++ + E + L Sbjct: 8 KTRSLCPECLRPVDAEVFEDEGRVLIRKECPEHGKFENVYWSNSKIYHKAEEYDEEGEGL 67 Query: 113 FSVNVENTGVNCPFDCGLCARHRSHTSLLNIVLTNRCNLNCWYCF 157 + + CP DCGLC H SHT L I +TNRCNL C CF Sbjct: 68 LNPQTDPLK-GCPMDCGLCPEHESHTVLGLIDVTNRCNLKCPICF 111 >sp|Q58036|Y619_METJA HYPOTHETICAL PROTEIN MJ0619 >gi|2128410|pir||C64377 hypothetical protein MJ0619 - Methanococcus jannaschii >gi|1591330|gb|AAB98614.1| (U67510) conserved hypothetical protein [Methanococcus jannaschii] Length = 506 Score = 336 bits (852), Expect = 9e-91 Identities = 179/401 (44%), Positives = 261/401 (64%), Gaps = 18/401 (4%) Query: 611 CFFYAREGEPIYEPTLEQIRMMLRNAKKEHPIGANAVQFTGGEPTLRDDLIEIIKIAKEE 670 CF A + +YEP+ E I+ M+ N +KE P A+QF GGEPT+R DL E+IK+A++ Sbjct: 105 CFANANKSGKVYEPSFEDIKRMMENLRKEIP-PTPAIQFAGGEPTVRSDLPELIKLARDM 163 Query: 671 GYDHVQLNTDGIKLAFDPELVKKIRQAGVNTLYLSYDGMTPQ----TNWKNHWEIPL-IF 725 G+ HVQL T+GIKL + +KK+++AG++T+YL +DG++ + KN I + Sbjct: 164 GFLHVQLATNGIKLK-NINYLKKLKEAGLSTIYLQFDGISEKPYLVARGKNLLPIKQKVI 222 Query: 726 ENVRKAGGPGIVLVPTLIRNVNDHEAGAIINFGLNHLDIVRGVNFQPISLVGRVPKKERQ 785 EN +K G +VLVPTL+R VND+E G II + ++D+VRG+NFQP+S GRV +K Sbjct: 223 ENCKKVGFDSVVLVPTLVRGVNDNEVGGIIRYAAENVDVVRGINFQPVSFTGRVDEKTLL 282 Query: 786 RFRITIAGAIKKIEEQTNGVISKDDWYPIPIAGHIARFFEVFTGS-KYYMTSHFACGAAT 844 RITI IK +EEQT+G I+++D+YP+P I+ E T K ++SH CG +T Sbjct: 283 EGRITIPDFIKLVEEQTDGEITEEDFYPVPSVAPISVLVEKLTNDRKPTLSSHQHCGTST 342 Query: 845 YVFLDREEKKVIPIPRFLDVEGFVEFLLEKAEEIEKARFKGLAKLKAIGETVFIKFKQFY 904 YVF+D E+ K+IPI RF+DVEGF+E + EK EEI K++ + +K +GE + +K Sbjct: 343 YVFVD-EDGKLIPITRFIDVEGFLEIVKEKIEEIGKSK---MHDVKVLGE-IALKLPSLI 397 Query: 905 DEKNAPKGLDVLGLIK--NAFVHGNYDALGKFHMNTLFLGMMHFMDEYNYDVERVERCVI 962 D APK +++ +I + + +Y AL + H + L + MHFMD YN+DV+RV RC I Sbjct: 398 DLDKAPKSVNIKKIIDLILSVLKSDYSALAELHYHMLMISCMHFMDAYNFDVKRVMRCCI 457 Query: 963 HYAMPDGRIVPFCTFNVIPELYRDKVQRQFSYSWEEWKKLH 1003 HYA PD RI+PFCT+N L+R +V+ +FS EEWK++H Sbjct: 458 HYATPDDRIIPFCTYNT---LHRQEVEEKFSIPLEEWKRMH 495 Score = 108 bits (266), Expect = 5e-22 Identities = 57/131 (43%), Positives = 79/131 (59%), Gaps = 12/131 (9%) Query: 54 RTYSLCPETRRVVPAVVWEKDGKVWITKKCPE-GMITDLYYEDVELYYRFSRWKFEEKKL 112 +T SLCP + +PA + E+DGK+ I K CPE G D+Y+ D ELY +F +++F K Sbjct: 4 KTLSLCPICLKRIPATILEEDGKIIIKKTCPEHGEFKDIYWGDAELYKKFDKYEFIGK-- 61 Query: 113 FSVNVENTGVN--CPFDCGLCARHRSHTSLLNIVLTNRCNLNCWYCFPPTEEAVFKFGDK 170 + V NT V CP+DCGLC H+S T L NI +TNRCNLNC CF ++ K Sbjct: 62 --IEVTNTKVKNGCPYDCGLCPNHKSTTILANIDVTNRCNLNCPICFANANKS-----GK 114 Query: 171 VKIATFEEVAK 181 V +FE++ + Sbjct: 115 VYEPSFEDIKR 125 >sp|Q58454|YA54_METJA HYPOTHETICAL PROTEIN MJ1054 >gi|2129344|pir||E64431 UDPglucose 6-dehydrogenase (EC 1.1.1.22) (intein-containing) - Methanococcus jannaschii >gi|1591706|gb|AAB99056.1| (U67548) UDP-glucose dehydrogenase, putative [Methanococcus jannaschii] Length = 895 Score = 152 bits (381), Expect = 2e-35 Identities = 130/481 (27%), Positives = 225/481 (46%), Gaps = 49/481 (10%) Query: 156 CFPPTEEAVFKFGDKVKIATFEEVAKNFKFEHKVEIDGFKGEYSIPNDLYVLTFNDGKAE 215 CF P E G ++ TF+E+ F+ E K +++ +L+F+ K Sbjct: 261 CFHPDEVLFIDRGRGLECITFKEL---FELEDK-------------DNVKILSFDGEKLS 304 Query: 216 WTRVTKFLRRKHEGKIRVIKTKTGRTIRTTPEHKFFVYKDGELVKKRADELEPGDELVLL 275 ++ +R + + ++ GR I+ T +H + +DGEL K +++ GD+++L Sbjct: 305 LKKLKLASKRYYNDDLITLRFNLGREIKITKDHPVVILEDGELKIKLTSDVKEGDKVILP 364 Query: 276 WRFESEETLTEINLLEAFKDLPQEEKEKVYVRGIKDLDLTPLKEKYGDKVYYWAR----- 330 + EE EI++LE EK ++ + + + +K +K + + Sbjct: 365 YGNFGEEREIEIDILEELSKTDLIEKVWIHNKDLATNEFNIIKPYLSNKYPHDVKRNGTI 424 Query: 331 --QDSMPLSVFYELNVDLDKEFRLGRDATTYELPSKLKITPSLAKLIGYFVSDGNYSDKD 388 +D +P+ + ++ F +TT +P K+KI A+LIGY++S+G + KD Sbjct: 425 RAKDILPIKEILDKYGSKNRLFTAKSKSTT--IPYKIKIDKDFARLIGYYLSEG-WISKD 481 Query: 389 ------------LRITVGHEDVEKEIVNILEELGLPYSFLEWEGKTKQIVIGSRLLRLVF 436 L + E+ ++ NIL +LG+ Y +G + I+I S++L VF Sbjct: 482 YGRNGVVRKRIGLCFGIHEEEYINDVKNILNKLGIKYIEKIKDG-SHSILISSKILAYVF 540 Query: 437 KHVFKIPEGAPNKRLPEGFLSFPFEAKVALLSGLFNGDGYVVR--GEHHLSIGYASTSKG 494 +++ NK +P + E K L GLF GDG +VR +L+I +A+ SK Sbjct: 541 ENILNCGINCYNKNIPPQMFNAKEEIKWEFLKGLFRGDGGIVRLNNNKNLNIEFATVSKK 600 Query: 495 LIRDILYLLASLGIFARVYRVPKEKMKGANHDLYKLYIAGTDLVRLV-ELLELREGHREK 553 + +L LL LGI A V + K + Y + I G + V+ + EL + + + Sbjct: 601 MAHSLLILLQLLGIVASVKKCYNNK---STTMAYIIRINGLEQVKKIGELFGKKWENYKD 657 Query: 554 LGEIGNR--KPARVKKIADFYIDVVDEVSEEEYSGYVYDLEVENEGHSFVAADGILVSNC 611 + E R +P KK +F I V E+ +E YSGYVY +E EN + + GIL+ NC Sbjct: 658 IAESYKRNIEPLGYKKSDNFAILEVKEIIKEHYSGYVYSVETENS--LLITSYGILIHNC 715 Query: 612 F 612 F Sbjct: 716 F 716 >dbj|BAA06142.2| (D29671) DNA-dependent DNA polymerase [Pyrococcus sp.] Length = 1671 Score = 116 bits (289), Expect = 9e-25 Identities = 135/534 (25%), Positives = 227/534 (42%), Gaps = 111/534 (20%) Query: 177 EEVAKNFKFEHKVEIDGFKGEYSIPNDLYVLTFN--DGKAEWTRVTKFLRRKHEGKIRVI 234 EE A K E + E+ G L V +FN KAE RV +R + GK+ I Sbjct: 881 EENAGKVKREGETEVLEVSG-------LEVPSFNRRTNKAELKRVKALIRHDYSGKVYTI 933 Query: 235 KTKTGRTIRTTPEHKFFVYKDGELVKKRADELEPGDELVLLWRFESEETLTEINLLEAFK 294 + K+GR I+ T H F ++GELV+ DEL+PGD + + R E E +NL+E Sbjct: 934 RLKSGRRIKITSGHSLFSVRNGELVEVTGDELKPGDLVAVPRRLELPERNHVLNLVELLL 993 Query: 295 DLPQEEKEKV-----------------------------------YVRGIKDLDLTPLKE 319 P+EE + Y+R ++DL LK Sbjct: 994 GTPEEETLDIVMTIPVKGKKNFFKGMLRTLRWIFGEEKRPRTARRYLRHLEDLGYVRLK- 1052 Query: 320 KYGDKVYYW----------------ARQDSMPLSVFYELNVDLD----------KEFRLG 353 K G +V W R + E N D KE+++G Sbjct: 1053 KIGYEVLDWDSLKNYRRLYEALVENVRYNGNKREYLVEFNSIRDAVGIMPLKELKEWKIG 1112 Query: 354 RDATTYELPSKLKITPSLAKLIGYFVSDGNYSDKDLRITVGHE------DVEKEIVNILE 407 + + +++ SLAKL+GY+VS+G Y+ K G + + E+++ +E Sbjct: 1113 T-LNGFRMRKLIEVDESLAKLLGYYVSEG-YARKQRNPKNGWSYSVKLYNEDPEVLDDME 1170 Query: 408 ELGLPYSFLEWEGKTKQIVIGSRLLRLVFKHVFKIPEGAPNKRLPEGFLSFPFEAKVALL 467 L + G+ + I ++ L+F+++ + A NKR+PE + P ++A L Sbjct: 1171 RLASRFFGKVRRGRN-YVEIPKKIGYLLFENMCGVL--AENKRIPEFVFTSPKGVRLAFL 1227 Query: 468 SGLFNGDGYVVRGEHHLSIGYASTSKGLIRDILYLLASLGIFA----------RVY---- 513 G F GDG V + + ++ S+ L ++ LL S+G+ A RVY Sbjct: 1228 EGYFIGDGDVHPNKR---LRLSTKSELLANQLVLLLNSVGVSAVKLGHDSGVYRVYINEE 1284 Query: 514 ----RVPKEKMKGANHDLYKLYIAGTDLVRLVELLELREGHREKLGEIGNRKPARVKKIA 569 ++ K+K +H + K ++ ++ V + K+ E G P + ++++ Sbjct: 1285 LPFVKLDKKKNAYYSHVIPKEVLS--EVFGKVFQKNVSPQTFRKMVEDGRLDPEKAQRLS 1342 Query: 570 -----DFYIDVVDEVSEEEYSGYVYDLEVENEGHSFVAADGILVSNCFFYAREG 618 D +D V+ V E+Y GYVYDL VE + +F+ G++ ++ +Y G Sbjct: 1343 WLIEGDVVLDRVESVDVEDYDGYVYDLSVE-DNENFLVGFGLVYAHNSYYGYYG 1395 >sp|O59610|DPOL_PYRHO DNA POLYMERASE >gi|7446920|pir||C71210 probable DNA-directed DNA polymerase - Pyrococcus horikoshii >gi|3258391|dbj|BAA31074.1| (AP000007) 1235aa long hypothetical DNA-directed DNA polymerase [Pyrococcus horikoshii] Length = 1235 Score = 112 bits (277), Expect = 2e-23 Identities = 142/545 (26%), Positives = 228/545 (41%), Gaps = 127/545 (23%) Query: 133 RHRSHTSLLNIVLTNRCNLNCWYCFPPTEEAVF-KFGDKVKIATFEEVAKNFKFEHKVEI 191 R R+ L N +L + W E+ F K GD + EE A+ K + + EI Sbjct: 483 RQRAIKILANSILPDE-----WLPIVENEKVRFVKIGDFID-REIEENAERVKRDGETEI 536 Query: 192 DGFKGEYSIPNDLYVLTFN--DGKAEWTRVTKFLRRKHEGKIRVIKTKTGRTIRTTPEHK 249 K DL L+FN K+E +V +R ++ GK+ IK K+GR I+ T H Sbjct: 537 LEVK-------DLKALSFNRETKKSELKKVKALIRHRYSGKVYSIKLKSGRRIKITSGHS 589 Query: 250 FFVYKDGELVKKRADELEPGDELVLLWRFESEETLTEINLLEAFKDLPQEEKEKVY---- 305 F K+G+LVK R DEL+PGD +V+ R + E+ +NL+E LP+EE + Sbjct: 590 LFSVKNGKLVKVRGDELKPGDLVVVPGRLKLPESKQVLNLVELLLKLPEEETSNIVMMIP 649 Query: 306 VRGIKDLDLTPLKEKY-----GDKVYYWARQ--------------------DSMPLSVFY 340 V+G K+ LK Y G++ R D L + Sbjct: 650 VKGRKNFFKGMLKTLYWIFGEGERPRTAGRYLKHLERLGYVKLKRRGCEVLDWESLKRYR 709 Query: 341 ELNVDLDKEFRLGRDATTYELP-SKLKITPSLAKL---------------IGYFVSDGNY 384 +L L K + ++ Y + + L+ SL + IG F+ + Sbjct: 710 KLYETLIKNLKYNGNSRAYMVEFNSLRDVVSLMPIEELKEWIIGEPRGPKIGTFIDVDDS 769 Query: 385 SDKDLRITVGHEDVEKEIV-------NILEELGLPYSFLEWEGKTKQ----IVIGSRLLR 433 K L + DVEK+ V N+LE++ L GK ++ I + ++ Sbjct: 770 FAKLLGYYISSGDVEKDRVKFHSKDQNVLEDIAKLAEKL--FGKVRRGRGYIEVSGKISH 827 Query: 434 LVFKHVFKIPEGAPNKRLPEGFLSFPFEAKVALLSGLFNGDGYVVRGEHHLSIGYASTSK 493 +F+ + A KR+PE + P + KVA L GL NG+ + +++ S+ Sbjct: 828 AIFRVL------AEGKRIPEFIFTSPMDIKVAFLKGL-NGNAE--------ELTFSTKSE 872 Query: 494 GLIRDILYLLASLGIFARVYRVPKEKMKGANHDLYKLYIAGTDLVRLVELLELREGHREK 553 L+ ++ LL S+G V + E KG +Y++YI Sbjct: 873 LLVNQLILLLNSIG----VSDIKIEHEKG----VYRVYI--------------------- 903 Query: 554 LGEIGNRKPARVKKIADFYIDVVDEVSEEEYSGYVYDLEVENEGHSFVAADGILVSNCFF 613 N+K + D +D V+ + E+Y GYVYDL VE + +F+ G+L ++ + Sbjct: 904 -----NKKES---SNGDIVLDSVESIEVEKYEGYVYDLSVE-DNENFLVGFGLLYAHNSY 954 Query: 614 YAREG 618 Y G Sbjct: 955 YGYYG 959 >pir||B70797 probable transferase - Mycobacterium tuberculosis (strain H37RV) >gi|2960153|emb|CAA18051.1| (AL022121) hypothetical protein Rv3729 [Mycobacterium tuberculosis] Length = 776 Score = 104 bits (257), Expect = 5e-21 Identities = 89/359 (24%), Positives = 163/359 (44%), Gaps = 47/359 (13%) Query: 647 VQFTGGEPTLRDDLIEIIKIAKEEGYDHVQLNTDGIKLAFDPELVKKI----RQAGVNTL 702 V F+GGEPT+ L+E + A+ V +NT+GI+LA D V ++ R + Sbjct: 142 VMFSGGEPTIHKQLLEFVDAAQARPVKTVIINTNGIRLASDRRFVDQLATRNRPGHPVHI 201 Query: 703 YLSYDGMTPQTNWK----NHWEIPLIFENVRKAGGPGIVLVPTLIRNVNDHEAGAIINFG 758 YL +DG+ T+ + + ++ + A G + LV + R +N+HE GA+I G Sbjct: 202 YLQFDGLDEATHRRIRGHDLRDVKQRALDNCAAAGLTVSLVAAVERGLNEHELGAVIRHG 261 Query: 759 LNHLDIVRGVNFQPISLVGRVPKKERQRFRITIAGAIKKIEEQTNGVISKDDWYPIPIAG 818 + V+ V FQP++ GR + + R+T + I I Q D++P+P Sbjct: 262 MAQPG-VQPVVFQPVTHAGRHVQFD-PLTRLTNSDIIACITAQLPEWFRPGDFFPVPCC- 318 Query: 819 HIARFFEVFTGSKYYMTSHFACGAATYVFLDREEKKVIPIPRFLDVEGFVEFLLEKA--E 876 +C + TY+ D E V+PIPR L+VE +++++ + + Sbjct: 319 ------------------FPSCRSITYLLTDGEH--VVPIPRLLNVEDYLDYVSNRVIPD 358 Query: 877 EIEKARFKGLAKLKAI--GETVFIKFKQFYDEKNAPKGLDVLGLIKNAFVHGNYDALGKF 934 + + L A+ +T+ + ++ N +G + +AL Sbjct: 359 LAIREALENLWSASAVPGTDTMTAQLQRATAALNCAEGCGI----------NLPEALTHL 408 Query: 935 HMNTLFLGMMHFMDEYNYDVERVERCVIHYAMPDGRIVPFCTFNVIPELYRDKVQRQFS 993 + + F D Y +V+++ +C + PDGR++PFC +N + YR++V+ Q + Sbjct: 409 TDRVFAIVIQDFQDPYTLNVKQLMKCCVQQITPDGRLIPFCAYNSVG--YREQVREQLT 465 >sp|Q51334|DPOL_PYRSD DNA POLYMERASE (DEEP VENT DNA POLYMERASE) [CONTAINS: PI-PSP I ENDONUCLEASE] >gi|2129416|pir||S68593 DNA-directed DNA polymerase (EC 2.7.7.7) Vent, intein containing precursor - Pyrococcus sp >gi|825735|gb|AAA67130.1| (U00707) Deep Vent DNA polymerase and PI-PspI precursor [Pyrococcus sp.] Length = 1312 Score = 94.8 bits (232), Expect = 5e-18 Identities = 115/492 (23%), Positives = 206/492 (41%), Gaps = 94/492 (19%) Query: 213 KAEWTRVTKFLRRKHEGKIRVIKTKTGRTIRTTPEHKFFVYKDGELVKKRADELEPGDEL 272 KA V +R ++ G + I +GR I T H FVY++G+LV+ ++++ GD L Sbjct: 553 KARVMAVKAVIRHRYSGNVYRIVLNSGRKITITEGHSLFVYRNGDLVEATGEDVKIGDLL 612 Query: 273 VLLWRFESEETLTEINLLEAFKDLPQEEKEKV---------------------------- 304 + E +N++E +L EE E + Sbjct: 613 AVPRSVNLPEKRERLNIVELLLNLSPEETEDIILTIPVKGRKNFFKGMLRTLRWIFGEEK 672 Query: 305 -------YVRGIKDLDLTPLK------------EKYG---DKVYYWARQDSMPLSVFYEL 342 Y+R +++L L+ EKY +K+ R + E Sbjct: 673 RVRTASRYLRHLENLGYIRLRKIGYDIIDKEGLEKYRTLYEKLVDVVRYNGNKREYLVEF 732 Query: 343 NVDLD----------KEFRLGRDATTYELPSKLKITPSLAKLIGYFVSDGNY-----SDK 387 N D KE+R+G + + + + I AKL+GY+VS+G+ Sbjct: 733 NAVRDVISLMPEEELKEWRIGT-RNGFRMGTFVDIDEDFAKLLGYYVSEGSARKWKNQTG 791 Query: 388 DLRITVGHEDVEKEIVNILEELGLPYSFLEWEGKTKQIVIGSRLLRLVFKHVFKIPEGAP 447 TV + E+++ +E L + GK + I ++ ++F+ + A Sbjct: 792 GWSYTVRLYNENDEVLDDMEHLAKKFFGKVKRGKN-YVEIPKKMAYIIFESLCGTL--AE 848 Query: 448 NKRLPEGFLSFPFEAKVALLSGLFNGDGYVVRGEHHLSIGYASTSKGLIRDILYLLASLG 507 NKR+PE + + A L G F GDG V + + ++ S+ L+ ++ LL SLG Sbjct: 849 NKRVPEVIFTSSKGVRWAFLEGYFIGDGDVHPSKR---VRLSTKSELLVNGLVLLLNSLG 905 Query: 508 IFA-------RVYRV-PKEKMKGANH----DLYKLYIAGTDLVRLV--ELLELREGHRE- 552 + A VYRV E++K + ++Y +I D+++ ++ + +++ Sbjct: 906 VSAIKLGYDSGVYRVYVNEELKFTEYRKKKNVYHSHIVPKDILKETFGKVFQKNISYKKF 965 Query: 553 ----KLGEIGNRKPARVKKI--ADFYIDVVDEVSEEEYSGYVYDLEVENEGHSFVAADGI 606 + G++ K R++ + D +D V E+ E Y GYVYDL V+ E +F+A G Sbjct: 966 RELVENGKLDREKAKRIEWLLNGDIVLDRVVEIKREYYDGYVYDLSVD-EDENFLAGFGF 1024 Query: 607 LVSNCFFYAREG 618 L ++ +Y G Sbjct: 1025 LYAHNSYYGYYG 1036 >sp|Q58242|Y832_METJA HYPOTHETICAL PROTEIN MJ0832 >gi|2129243|pir||H64403 ribonucleoside-triphosphate reductase (EC 1.17.4.2), anaerobic (intein-containing) - Methanococcus jannaschii >gi|1591520|gb|AAB98834.1| (U67527) anaerobic ribonucleoside-triphosphate reductase (nrdD) [Methanococcus jannaschii] Length = 1750 Score = 88.2 bits (215), Expect = 4e-16 Identities = 110/455 (24%), Positives = 215/455 (47%), Gaps = 52/455 (11%) Query: 159 PTEEAVFKFGDK----VKIATFEEVAKNFKFEHKVEIDGFKGEYSIPND-LYVLTFN-DG 212 P +E + F + VKI F E N + + E I ++ +Y +F+ DG Sbjct: 1061 PYDEKILIFENNEYKLVKIGEFVEKYLNRYKDRAITYGDNNIEVYIKDENIYAPSFDKDG 1120 Query: 213 KAEWTRVTKFLRRKHEGK-IRVIKTKTGRTIRTTPEHKFFVYKDG-ELVKKRADELEPGD 270 K +T +R H GK I I+ ++G+ +R T +H F D ++V+ +A +L+ GD Sbjct: 1121 KIVLKPITHAIR--HRGKEIYEIELESGKKVRVTGDHSVFTINDNLDVVEVKASDLKVGD 1178 Query: 271 ELVLLWRFESEETLTEINLLEAFKDLPQEEKEKVYVRGIKDL------DLTPLKEKYGDK 324 ++ + + + I+ + + + K+K YV+ IKD LKE Y + Sbjct: 1179 FII------TPKIIPSISKDKIYLSEIVKNKDKYYVK-IKDHIKFIEEHEEILKESYKEY 1231 Query: 325 VYYWA-------RQDSMPLSVFYELNVDLDKEFRLGRDATTYELPSKLKITPSLAKLIGY 377 W ++++ L + +L VD +K ++ Y + +K+K+ LIG Sbjct: 1232 KTKWKDLKPVLKKKNAFRLDLIEDL-VDKEKIEKISYGHANY-INNKIKLDEKFGYLIGA 1289 Query: 378 FVSDGNYSDKDLRITVGHEDVEKEIVNILEE-LGLPYSFLEWEGKTKQ----IVIG-SRL 431 F+S+G+++DK + I+ +++ + +V I+EE LG ++ +G ++ VIG ++ Sbjct: 1290 FLSEGHWNDKCVEISSTNKEFIENLVEIIEEILGKDAYYITVKGDKRRYKDLYVIGLNKT 1349 Query: 432 LRLVFKHVFKIPEGAPNKRLPEGFLSFPFEAKVALLSGLFNGDG--YVVRGEHHLSIGYA 489 + ++F+ + + + + NK +P LS K L+ G +GDG YV + SI Sbjct: 1350 VAMIFESL-GLNKLSSNKEIPSILLSNETFLK-GLIKGYIDGDGSIYVDESKRDYSIRLY 1407 Query: 490 STSKGLIRDILYLLASLGIFARVYRVPKEKMKGANHDLYKLYIAGTDLVRLVELLELREG 549 +TS+ L + L LGI R+ K K+ D Y + I G + + + +E++ Sbjct: 1408 TTSETLRDTLCLALKILGINYRLSIDKKSKVNENWRDCYVIKITGKENIEKLLDVEIKNN 1467 Query: 550 HREKLGEIGNRKPARVKKIADFYIDVVDEVSEEEY 584 + + + KIA+ + +++++ S+ E+ Sbjct: 1468 GGKDV----------IPKIAEKFKEIINQYSQREW 1492 Score = 83.1 bits (202), Expect = 1e-14 Identities = 88/348 (25%), Positives = 147/348 (41%), Gaps = 84/348 (24%) Query: 338 VFYELNVDLDKEFRLG--------RDATTY-----ELPSKLKITPSLAKLIGYFVSDGNY 384 + N D E+R+G R + Y ++P KLKIT L + +G FV++G+Y Sbjct: 458 IIRNFNNPYDVEYRIGDYIETNYQRTDSKYNSRQNDIPEKLKITKELCQFLGLFVAEGSY 517 Query: 385 SDKDLRITVGHEDVEKEIVN-ILEELGLPYSFLEWEGKTKQIVIGSRLLRLVFKHVFKIP 443 + IT +D+ K I + E++ + +E + + R + +H I Sbjct: 518 ITNGISITTKDDDIAKFIERFVKEQINENIAVKRYEDSVR--FVNKGFYRFLKEH---IN 572 Query: 444 EGAPNKRLPEGFLSFPFEAKVALLSGLFNGDGYVVRGEHHLSIGYASTSKGLIRDILYLL 503 A NK PE L E K+A L GL +GDGYV + + +TS+ L+ + LL Sbjct: 573 GKAINKNSPEFILKGDKEMKLAFLGGLISGDGYVSKDGR---VQIYTTSEQLLGQLHLLL 629 Query: 504 ASLGIFARVYRVPKEKMKGANHDL--------YKLYIA------------------GTDL 537 + LG+ +Y + K K +G ++ YKLY+ + Sbjct: 630 SDLGM---IYSITKIKEEGEKIEIKRNEIVRNYKLYVIEIAKNCTEDLKPYVIPKYKKER 686 Query: 538 VRLVELLELREGHR---EKLGEIGNRKPAR--------------------------VKKI 568 ++ +L +R E L +I ++KP ++I Sbjct: 687 IKPANYDQLPYDYRIIKEHLRKITDKKPYNDYAWKSNNRKLKLNTLEKIEQLNPHLREEI 746 Query: 569 ADFYIDV---VDEVSEEEYSGYVYDLEVENEGHSFVAADGILVSNCFF 613 F +++ + E+ E +Y+GYVYDL VE + +F+ A GIL N F Sbjct: 747 NKFKLNIPFEIKEIKEIDYNGYVYDLSVE-DNENFITATGILCHNTIF 793 >emb|CAC18555.1| (AJ245819) DNA polymerase and endonucleases [Thermococcus hydrothermalis] Length = 1668 Score = 84.7 bits (206), Expect = 5e-15 Identities = 122/493 (24%), Positives = 195/493 (38%), Gaps = 96/493 (19%) Query: 213 KAEWTRVTKFLRRKHEGKIRVIKTKTGRTIRTTPEHKFFVYKDGELVKKRADELEPGDEL 272 KA V +R ++ G + I +GR I T H F Y DGEL + E++ GD L Sbjct: 519 KARVMPVKAVIRHRYSGDVYEIVLGSGRRITVTEGHSLFAYGDGELREVTGGEIKAGDLL 578 Query: 273 V------------------LLWRFESEETLTEI-------------NLLEAFKDLPQEEK 301 LL R EET I +L + + EEK Sbjct: 579 AVPRRVNLPEKKERLNLVELLRRLPEEETGDIILTIPVKGRKNFFKGMLRTLRWISGEEK 638 Query: 302 E----KVYVRGIKDLDLTPLKE---------------KYGDKVYYWARQDSMPLSVFYEL 342 + Y+ ++ L LK+ K +++ R + E Sbjct: 639 RPRTARRYLEHLEGLGYVRLKKIGYEVTDREGLERYRKLYERLVEAVRYNGNKREYLVEF 698 Query: 343 NVDLD-------KEFR--LGRDATTYELPSKLKITPSLAKLIGYFVSDGNY-----SDKD 388 N D +E R L + + ++I AKL+GY+VS+GN Sbjct: 699 NAVRDVIALMPEEELRDWLVGTRNGFRMRPFVEIEEDFAKLLGYYVSEGNARKWRNQKNG 758 Query: 389 LRITVGHEDVEKEIVNILEELGLPYSFLEWEGKTKQIVIGSRLLRLVFKHVFKIPEGAPN 448 TV + + +++ +E L + GK I I ++ ++F+++ A N Sbjct: 759 WSYTVKLYNENQRVLDDMESLAERFFGRVKRGKN-YIEIPRKMAYIIFENLCGTL--AEN 815 Query: 449 KRLPEGFLSFPFEAKVALLSGLFNGDGYVVRGEHHLSIGYASTSKGLIRDILYLLASLGI 508 KR+PE + P + A + G F GDG V + + ++ S+ L+ ++ LL SLG+ Sbjct: 816 KRVPEAIFTSPESVRWAFIEGYFIGDGDVHPSKR---VRLSTKSELLVNGLVLLLNSLGV 872 Query: 509 FA-------RVYRV-----------PKEKMKGANHDLYKLYIA---GTDLVRLVELLELR 547 A VYRV K+K +H + K + G R V + R Sbjct: 873 SAIKIRHDSGVYRVYVNEELPFTDYRKKKNAYYSHVIPKEILEETFGKVFQRSVSYEKFR 932 Query: 548 EGHREKLGEIGNRKPARVKKI--ADFYIDVVDEVSEEEYSGYVYDLEVENEGHSFVAADG 605 E K ++ K R++ + D +D V EV + Y GYVYDL VE E +F+A G Sbjct: 933 E--LVKSEKLDGEKAKRIEWLLNGDVVLDKVLEVKKRPYEGYVYDLSVE-EDENFLAGFG 989 Query: 606 ILVSNCFFYAREG 618 +L ++ +Y G Sbjct: 990 LLYAHNSYYGYYG 1002 Score = 72.6 bits (175), Expect = 2e-11 Identities = 69/255 (27%), Positives = 114/255 (44%), Gaps = 16/255 (6%) Query: 367 ITPSLAKLIGYFVSDGNYSDKD--------LRITVGHEDVEKEIVNILEELGLPYSFLEW 418 I L +LIG V DGN+ + L + + E++E++I+ L+ G+ ++ + Sbjct: 1184 IAVKLWELIGLLVGDGNWGGQSNWAKYNVGLSLGLDKEEIEEKILKPLKNTGIISNYYDK 1243 Query: 419 EGKTKQIVIGSRLLRLVFKHVFKIPEGAPNKRLPEGFLSFPFEAKVALLSGLFNGDGYVV 478 K ++ L R + ++ FK G+ KR+PE + P E A L GLF+ DG V Sbjct: 1244 SKKGDVSILSKWLARFMVRY-FKDESGS--KRIPEFMFNLPREYIEAFLRGLFSADGTVS 1300 Query: 479 RGEHHLSIGYASTSKGLIRDILYLLASLGIFARVY-RVPKEKMKGANHDLYKLYIAGTDL 537 + + S + L + LL +G+ ++ + G + +++ D Sbjct: 1301 LRKGVPEVRLTSVNPELSSSVRKLLWLVGVSNSMFVETNPNRYLGKESGTHSVHVRIKDK 1360 Query: 538 VRLVELLE-LREGHREKLGE-IGNRKPARVKKIADFYIDVVDEVSEEEYSGYVYDLEVEN 595 R E + L + KL E +G + DF + +V E Y GYVYD+EVE Sbjct: 1361 HRFAERIGFLLDRKATKLSENLGGHTSKKRAYKYDFDLVYPKKVEEIAYDGYVYDIEVEG 1420 Query: 596 EGHSFVAADGILVSN 610 F A+GILV N Sbjct: 1421 THRFF--ANGILVHN 1433 >pir||B72665 hypothetical protein APE0745 - Aeropyrum pernix (strain K1) >gi|5104407|dbj|BAA79722.1| (AP000060) 726aa long hypothetical protein [Aeropyrum pernix] Length = 726 Score = 84.3 bits (205), Expect = 7e-15 Identities = 116/497 (23%), Positives = 193/497 (38%), Gaps = 69/497 (13%) Query: 158 PPTEEAVFKFGDKVKIATFEEVAKNF-KFEHKVEIDGFKGEYSIPNDLYVLTFNDGKAEW 216 PP E V + GD+V++ + E +F + E ++I G G Y++ D L K W Sbjct: 178 PPWEPIVVRRGDEVRVTSIGEFVDSFLEGEGGLDIGGL-GYYTLSLDTRTL-----KPVW 231 Query: 217 TRVTKFLRRKHEGKIRVIKTKTGRTIRTTPEHKFF-VYKDGELVKKRADELEPGDELVLL 275 R+ ++ + G++ +K GR+I T H + + + G L + +L PGD LV Sbjct: 232 RRIRGVIKHRIRGRLLRVKASKGRSIDLTGSHSIYRISRGGGLEVVGSSDLRPGDSLVTP 291 Query: 276 WRFESEETLTEINLLEAFKDLPQEEKEKVYVRGIKD-------------------LDLTP 316 E E+ + + A ++L E ++V G+ + L Sbjct: 292 ASVELPESAP--SSINAARELWSRGVEGIFVVGLPGEAAGYRGVERSRGYDGGHAIPLET 349 Query: 317 LKEKYGDKVYYWARQDSMPLSVFYELNVDLDKEFRLGRDATTYELPSKLKITPSLAKLIG 376 L E+YGD V W+ L+V A + +P+ + + L+G Sbjct: 350 LVERYGDSV--WSLVSGAKLAVSRGA-------------AGDHPVPATIPLDTGFYLLLG 394 Query: 377 YFVSDGNYSDKDLRITV----GHEDVEKEIVNILEELGLPYSFLEWEG-KTKQIVIGSRL 431 + VS G+ + +TV G E ++V + G + ++ I SR+ Sbjct: 395 FIVSAGSVDVEGGHVTVTLGPGREGYVGDVVEAVNSTAPGAGVRISSGARGMEVTIRSRV 454 Query: 432 LRLVFKHVFKIPEGAPNKRLPEGFLSFPFEAKVALLSGLFNGDGYVVRGEHHLSIGYAST 491 L + VF G PN+ +P P K L GL+ G G R S+ YA+ Sbjct: 455 LSELLARVFGAGPG-PNRDIPSIVFRAPKPMKRVFLKGLYAGGGVFDRSSG--SLIYATD 511 Query: 492 SKGLIRDILYLLASLGIFARVYRVPK--------------EKMKGANHDLYKL-YIAGTD 536 S+ L+ + LL ++G A YR+ ++ L L + G + Sbjct: 512 SRSLLNGLALLLLNVG--AGGYRIDSGDSGRALALIVENAGRLDAIGEVLEHLGFHGGRE 569 Query: 537 LVRLVELLELREGHREKLGEIGNRKPARVKKIADFYIDVVDEVSEEEYSGYVYDLEVENE 596 V+ V LE + ++PA V E + +VYDL VE + Sbjct: 570 AVQGVGALERATAGLAGQATVAVQRPATRGGPGVDVAGVTGLEHLEASTEFVYDLSVEGD 629 Query: 597 GHSFVAADGILVSNCFF 613 + F ILV N F Sbjct: 630 ENFFAGLGWILVHNSAF 646 >sp|Q58815|YE20_METJA HYPOTHETICAL PROTEIN MJ1420 >gi|2127939|pir||C64477 glutamine--fructose-6-phosphate transaminase (isomerizing) (EC 2.6.1.16) (intein-containing) - Methanococcus jannaschii >gi|1592069|gb|AAB99430.1| (U67582) glucosamine--fructose-6-phosphate aminotransferase (isomerizing) (glmS) [Methanococcus jannaschii] Length = 1102 Score = 76.9 bits (186), Expect = 1e-12 Identities = 108/419 (25%), Positives = 184/419 (43%), Gaps = 65/419 (15%) Query: 170 KVKIATFEEVAKNFKFEHKVEIDGFKG-EYSIPNDLYVL--------------------T 208 K + EEVAK +F ++IDG G + + D YV+ Sbjct: 48 KKNVGKVEEVAKKERF---LDIDGNIGIGHCLHPDTYVILPDGRMKKISEIDEDEVLSVN 104 Query: 209 FNDGKAEWTRVTKFLRRKHEGKIRVIKTKTGRT-IRTTPEHKFFVYKDGELVKKRADELE 267 F D K ++ KF KH+ + K KT + + TT EHK FV ++G++V+K +L Sbjct: 105 FEDLKLYNKKIKKF---KHKAPKILYKIKTAFSELITTGEHKLFVVENGKIVEKCVKDLN 161 Query: 268 PGDELV-----LLWRFESEETLTEINLLEAFKDLPQEEKEKV-YVRGIKDLDLTPLKEKY 321 G EL+ L + F ++ + +K L + + K+ VR L +++ Sbjct: 162 -GSELIGVVRKLNYSFNDNVEFKDVYVERHYK-LDETIRNKLRKVREKLGLTRKDVEKLC 219 Query: 322 GDKVYYWARQDSMPLSVFYELNV-------DLDKEFRLGRDATTYELPSKLKITPS--LA 372 G K Y + ++ L E + ++ E + RD Y P K TP+ L Sbjct: 220 GVKEIYIVKIETGKLESIEEERLKKLCSLYGINFEEIIYRDNLHYTNPVKFPKTPTPELM 279 Query: 373 KLIGYFVSDGNY-SDKDLRITVGHEDVEKEIVNILEEL-GLPYSFLEWEGKTKQIVIGSR 430 ++IGY + DG++ S++ LR+ ++V +E + + + L + + +G + I S+ Sbjct: 280 QIIGYIIGDGHFPSNRMLRLKDERKEVLEEYNQLFKTVFNLEGNIKKGDGNYYILEINSK 339 Query: 431 LLRLVFKHVFKIPE---GAPNKRLPEGFLSFPFEAKVALLSGLFNGDGYVVRGEHHLSIG 487 L F+ IPE N+R PE + + L G+F+ +GY +R E IG Sbjct: 340 YLIDWFRE--NIPELFNKTGNERTPEFVFRLNNDLVASYLRGIFDAEGY-IRAEAK-QIG 395 Query: 488 YASTSKGLIRDILYLLASLGIFARVYRVPKEKMKGAN-----------HDLYKLYIAGT 535 TSK I++I +LL GI A ++ +++ N +L+K YI T Sbjct: 396 IGMTSKCFIKEIQFLLLRFGILASYSKIKRKEENWNNTHKLLISDKKSFELFKKYIGFT 454 >pir||C71110 hypothetical protein PH0650 - Pyrococcus horikoshii >gi|3257058|dbj|BAA29741.1| (AP000003) 1136aa long hypothetical protein [Pyrococcus horikoshii] Length = 1136 Score = 76.9 bits (186), Expect = 1e-12 Identities = 87/365 (23%), Positives = 152/365 (40%), Gaps = 56/365 (15%) Query: 224 RRKHEG-KIRVIKTKTGRTIRTTPEHKFFVYKDGELVKKRADELEPGDELVLLWRFESEE 282 RR EG K+ IKT+TG + T H F + +G++V+K A L+ GD + ++ Sbjct: 523 RRVREGEKLIRIKTRTGNEVILTRSHPLFAFSNGDVVRKEAGNLKVGDRVAVMMNPPKPP 582 Query: 283 TLTEINLLEAFKDLPQEEKEKVYVRGIKDLDLTPLKEKYGDKVYYWARQDSMPLSVFYEL 342 + L + + + V K + P K +K Y +S P+ + E+ Sbjct: 583 QTKAVVDLSIYAKI----SDYYLVPNGKGMIKVPNKGLPPEKAQYLVSVNSHPVKLVREV 638 Query: 343 NVDLDKEFRLGRDATTYELPSKLKITPSLAKLIGYFVSDGNYSDKDLRITVGHEDVEKEI 402 + KL + GY S+G Y + T ED + Sbjct: 639 D-------------------EKLSYLAGVILGDGYISSNGYY----ISATFDDEDYMEAF 675 Query: 403 VNILEELGLPY-SFLEWEGKTKQIVIGSRLLRLVFKHVFKIPEGAPNK-RLPEGFLSFPF 460 V+++ + Y ++ GK + +GS++ + +F IP+G + +P+ LS Sbjct: 676 VSVISDFIPNYIPNVKENGKYMVVTVGSKIFAEMLSRIFGIPKGRKLEWDVPDIVLSND- 734 Query: 461 EAKVALLSGLFNGDGYVVRGEHHLSIGYASTSKGLIRDILYLLASLGIFARVYRVPKEKM 520 + ++GLF+ DGYV SI + S+ + R I Y L LGI + V RV + Sbjct: 735 DLMRYFIAGLFDADGYVDEN----SIILVTKSENVARKIWYALQRLGIISTVSRVKNKGF 790 Query: 521 KGANHDLYKLYIAGTD----------------LVRLVELLELREGHREKLGEIGNRKPAR 564 K +++++ I+G D +L+E+L+ ++ HR G R P Sbjct: 791 K--EGEIFRVIISGVDDLAKFARSIPLHHSRKRAKLMEVLKTKKTHR---GRRAYRVPIS 845 Query: 565 VKKIA 569 + IA Sbjct: 846 AEMIA 850 >sp|Q58446|RPA2_METJA DNA-DIRECTED RNA POLYMERASE SUBUNIT A" >gi|2127865|pir||B64430 DNA-directed RNA polymerase (EC 2.7.7.6) subunit A'' (intein-containing) - Methanococcus jannaschii >gi|1591697|gb|AAB99047.1| (U67547) DNA-directed RNA polymerase, subunit A'' (rpoA2) [Methanococcus jannaschii] Length = 859 Score = 76.9 bits (186), Expect = 1e-12 Identities = 88/363 (24%), Positives = 148/363 (40%), Gaps = 68/363 (18%) Query: 158 PPTEEAVFKFGDKVKIATF----EEVAKNFKFEHKVEIDGFKGEYSIPNDLYVLTFN-DG 212 P E+ + K G+ +K +E+ + F FE K+ G +P D+Y L+ + D Sbjct: 78 PYEEKIIIKEGEFIKPVEIGKLVDEMIERFGFE-KI---GNSEVCDLPIDIYALSLDQDE 133 Query: 213 KAEWTRVTKFLRRKHEGKIRVIKTKTGRTIRTTPEHKFFVYKDGELVKKRADELEPGDEL 272 K W R+ +R KH GK+ IKTK+GR I TP H F + KD +++ + EL+ GD + Sbjct: 134 KVHWKRIISCIRHKHNGKLIKIKTKSGREITATPYHSFVIRKDNKIIPVKGSELKIGDRI 193 Query: 273 VLLWRFESEETLTEINLLEAFKDLPQEEKEKVYVRGIKDLDLTPLKEKYGDKVYYWARQD 332 ++ + + IN+ + YV G +D + K K+ Sbjct: 194 PVVKHIPA-NCVEAINISD-------------YVSGNYVVD--NINNKIAPKI------- 230 Query: 333 SMPLSVFYELNVDLDKEFRLGRDATTYELPSKLKITPSLAKLIGYFVSDGNYSDKDLRIT 392 +P+ +K+ IG ++++G+ + + I+ Sbjct: 231 ------------------------NGKSIPNNIKLDYDFGYFIGIYLAEGSVTKYFVSIS 266 Query: 393 VGHEDVEKEIVNILEELGLPYSFLEWE-----GKTKQIVIGSRLLRLVFKHVFKIPEGAP 447 E + +I ++LGL Y E++ ++ I I S L + + + Sbjct: 267 NVDELILNKIRAFADKLGLNYG--EYDNNNGFAESHDIRIYSSTLA---EFLSNFGTSSN 321 Query: 448 NKRLPEGFLSFPFEAKVALLSGLFNGDGYVVRGEHHLSIGYASTSKGLIRDILYLLASLG 507 K++ E E L+ G F+GDG V I S SK LI I LLA Sbjct: 322 TKKIAEFVFGANKEFVRGLIRGYFDGDGNV--NADRKVIRVTSNSKELIDGIAILLARFN 379 Query: 508 IFA 510 IF+ Sbjct: 380 IFS 382 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.321 0.141 0.422 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 418879563 Number of Sequences: 2977 Number of extensions: 19690237 Number of successful extensions: 47695 Number of sequences better than 1.0e-10: 19 Number of HSP's better than 0.0 without gapping: 9 Number of HSP's successfully gapped in prelim test: 10 Number of HSP's that attempted gapping in prelim test: 47589 Number of HSP's gapped (non-prelim): 48 length of query: 1042 length of database: 189,106,746 effective HSP length: 56 effective length of query: 986 effective length of database: 155,591,474 effective search space: 153413193364 effective search space used: 153413193364 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 41 (21.8 bits) S2: 170 (70.6 bits)