BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1929 (PAB1929) DE:ABC TRANSPORTER, ATP-BINDING PROTEIN
         (633 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||F75107 abc transporter, ATP-binding protein PAB1929 - Pyroc...  1281  0.0
pir||G71026 hypothetical protein PH1507 - Pyrococcus horikoshii ...  1244  0.0
gi|11498669 ABC transporter, ATP-binding protein, putative [Arch...   725  0.0
pir||D72453 hypothetical protein APE2272 - Aeropyrum pernix (str...   686  0.0
sp|O34900|YTMN_BACSU PROBABLE AMINO-ACID ABC TRANSPORTER ATP-BIN...    93  8e-18
emb|CAA11724.1| (AJ223978) putative ABC transporter, YvrO [Bacil...    88  3e-16
pir||C82957 probable ATP-binding component of ABC transporter PA...    87  4e-16
dbj|BAA76299.1| (AB003329) LAMDR1 [Leishmania amazonensis]             87  6e-16
pir||H82709 colicin V secretion ABC transporter ATP-binding prot...    86  1e-15
emb|CAB61549.1| (AL133171) putative ABC transporter [Streptomyce...    85  3e-15
pir||F71800 ABC transporter, ATP-binding protein - Helicobacter ...    84  4e-15
emb|CAB69672.1| (AL137165) probable ABC transporter protein, ATP...    84  4e-15
gb|AAC45666.1| (AF010307) AbcC [Helicobacter pylori]                   84  5e-15
sp|P44785|ABC_HAEIN ATP-BINDING PROTEIN ABC >gi|1073885|pir||C64...    84  5e-15
pir||D70020 ABC transporter (ATP-binding protein) homolog yusC -...    83  7e-15
pir||T22813 hypothetical protein F57A10.3 - Caenorhabditis elega...    83  7e-15
gb|AAA02976.1| (L06062) multi drug resistance P-glycoprotein [Le...    83  7e-15
gb|AAC31907.1| (AF075709) ABC transporter ATP-binding subunit [P...    83  9e-15
gb|AAA02977.1| (L01572) P-glycoprotein [Leishmania donovani]           83  9e-15
pir||G69192 ABC transporter (glutamine transport ATP-binding pro...    83  1e-14
emb|CAB01940.1| (Z79692) ExpD1 [Sinorhizobium meliloti]                82  1e-14
pir||G72255 ABC transporter, ATP-binding protein - Thermotoga ma...    82  1e-14
pir||A71243 probable maltose/maltodextrin transport ATP-binding ...    82  1e-14
dbj|BAB04005.1| (AP001508) ABC transporter (ATP-binding protein)...    82  1e-14
dbj|BAA77876.1| (D83536) ATP-binding protein ABC. [Escherichia c...    82  2e-14
sp|P54537|YQIZ_BACSU PROBABLE AMINO-ACID ABC TRANSPORTER ATP-BIN...    82  2e-14
pir||G81955 ABC-transport system ATP-binding protein NMA0393 [im...    82  3e-14
pir||E72757 probable phosphate transport ATP-binding protein pst...    81  3e-14
pir||G81012 spermidine/putrescine ABC transporter, ATP-binding p...    81  3e-14
dbj|BAB07610.1| (AP001520) ABC transporter (ATP-binding protein)...    81  3e-14
pir||T32865 hypothetical protein ZK484.2 - Caenorhabditis elegan...    80  6e-14
emb|CAB41455.1| (Y08703) ABC transporter [Sinorhizobium meliloti]      80  6e-14
pir||H64716 ABC transporter, ATP-binding protein - Helicobacter ...    80  6e-14
pir||G83214 probable ATP-binding component of ABC transporter PA...    80  6e-14
pir||F72510 probable multiple sugar-binding transport ATP-bindin...    80  6e-14
gi|10955699 ABC transporter [Yersinia pestis] >gi|7467316|pir||T...    80  7e-14
gi|10955870 putative ABC transporter [Yersinia pestis] >gi|74674...    80  7e-14
gb|AAB69130.1| (U63320) P-glycoprotein [Leishmania tropica]            80  7e-14
gi|11498288 glutamine ABC transporter, ATP-binding protein (glnQ...    80  7e-14
gi|9955963 ATP-binding cassette, sub-family B, member 6 [Homo sa...    80  7e-14
gb|AAC28653.1| (AF070598) ABC transporter [Homo sapiens]               80  7e-14
gb|AAG33617.1|AF308472_1 (AF308472) ATP-binding cassette half-tr...    80  7e-14
gb|AAA88774.1| (U47048) MtfB [Escherichia coli]                        80  1e-13
pir||H72704 probable iron (III) dicitrate transport ATP-binding ...    80  1e-13
pir||H70432 ABC transporter - Aquifex aeolicus >gi|2983897|gb|AA...    79  1e-13
pir||D75609 amino acid ABC transporter, ATP-binding protein - De...    79  1e-13
gb|AAF61810.1| (AF129811) unknown [Moraxella catarrhalis]              79  2e-13
sp|P73450|NRTC_SYNY3 NITRATE TRANSPORT ATP-BINDING PROTEIN NRTC ...    79  2e-13
pir||T37701 probable abc transporter - fission yeast (Schizosacc...    79  2e-13
pir||E71130 probable oligopeptide transport ATP-binding protein ...    79  2e-13
gb|AAF23272.1|AF101263_2 (AF121672) ABC transporter MreA [Staphy...    79  2e-13
emb|CAB65561.1| (AL136058) probable amino acid ABC transporter p...    79  2e-13
gb|AAF99566.1| (AF167161) unknown [Staphylococcus aureus]              79  2e-13
sp|O14286|YETI_SCHPO PUTATIVE ABC TRANSPORTER C8C9.18 IN CHROMOS...    79  2e-13
pir||E82539 ABC transporter ATP-binding protein XF2582 [imported...    78  2e-13
pir||D69180 ABC transporter - Methanobacterium thermoautotrophic...    78  2e-13
pir||H82381 toxin secretion ATP-binding protein VCA1084 [importe...    78  2e-13
emb|CAB65650.1| (AJ252160) putative ABC-transporter ATP-binding ...    78  2e-13
sp|P44531|AFUC_HAEIN PUTATIVE FERRIC TRANSPORT ATP-BINDING PROTE...    78  3e-13
pir||B64856 probable ABC-type transport protein ycfV - Escherich...    78  3e-13
pir||B70483 ABC transporter - Aquifex aeolicus >gi|2984332|gb|AA...    78  3e-13
sp|P75957|YCFV_ECOLI HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    78  3e-13
pir||C82266 ABC transporter, ATP-binding protein VC0907 [importe...    78  3e-13
dbj|BAA35937.1| (D90747) Heterocyst maturation protein (devA) ho...    78  3e-13
sp|Q02592|HMT1_SCHPO HEAVY METAL TOLERANCE PROTEIN PRECURSOR >gi...    78  4e-13
pir||T41582 heavy metal tolerance protein precursor - fission ye...    78  4e-13
pir||A82184 ABC transporter, ATP-binding protein VC1568 [importe...    78  4e-13
pir||S25198 vacuolar membrane protein HMT1 - fission yeast  (Sch...    78  4e-13
sp|Q06034|MDR1_LEIEN MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROT...    78  4e-13
sp|Q57293|AFUC_ACTPL FERRIC TRANSPORT ATP-BINDING PROTEIN AFUC >...    78  4e-13
sp|P75370|P29_MYCPN PROBABLE ABC TRANSPORTER ATP-BINDING PROTEIN...    77  5e-13
pir||D69068 methyl coenzyme M reductase system, component A2 hom...    77  5e-13
pir||T36053 probable ABC-type transport protein cydCD - Streptom...    77  5e-13
dbj|BAB03891.1| (AP001507) amino acid ABC transporter (ATP-bindi...    77  5e-13
dbj|BAB11402.1| (AP002543) ABC transporter-like protein [Arabido...    77  5e-13
sp|P34712|MDR1_CAEEL MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROT...    77  6e-13
pir||S25576 probable transport protein mt2 - rat >gi|407479|emb|...    77  6e-13
pir||S38402 probable transport protein mt2 - rat >gi|407481|emb|...    77  6e-13
sp|Q50294|Y179_MYCPN HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    77  6e-13
sp|Q9ZCM4|Y700_RICPR HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    77  6e-13
pir||T18940 multidrug resistance protein homolog - Caenorhabditi...    77  6e-13
pir||T23476 hypothetical protein K08E7.9 - Caenorhabditis elegan...    77  6e-13
sp|Q00449|MDR4_DROME MULTIDRUG RESISTANCE PROTEIN HOMOLOG 49 (P-...    76  9e-13
sp|P31134|POTG_ECOLI PUTRESCINE TRANSPORT ATP-BINDING PROTEIN PO...    76  9e-13
pir||S75960 nitrate transport protein D-1 - Synechocystis sp. (s...    76  9e-13
sp|Q47538|TAUB_ECOLI TAURINE TRANSPORT ATP-BINDING PROTEIN TAUB ...    76  9e-13
emb|CAB56736.1| (AL121600) ABC transport protein, ATP-binding su...    76  9e-13
gb|AAF58437.1| (AE003820) Mdr49 gene product [Drosophila melanog...    76  9e-13
pir||H82377 ABC transporter, ATP-binding protein VCA1101 [import...    76  9e-13
pir||G83607 polyamine transport protein PotG PA0302 [imported] -...    76  9e-13
dbj|BAB04534.1| (AP001509) ABC transporter (ATP-binding protein)...    76  9e-13
sp|P45022|YA78_HAEIN PROBABLE AMINO-ACID ABC TRANSPORTER ATP-BIN...    76  1e-12
pir||E69742 ABC transporter (ATP-binding protein) homolog ybaE -...    76  1e-12
pir||S77459 ABC-type transport protein slr1149 - Synechocystis s...    76  1e-12
gb|AAB58722.2| (AF001155) TAP2 [Mesocricetus auratus]                  76  1e-12
gb|AAB58724.2| (AF001157) TAP2 [Mesocricetus auratus]                  76  1e-12
dbj|BAB04930.1| (AP001511) ABC transporter (ATP-binding protein)...    76  1e-12
gb|AAG25076.1|AF273216_1 (AF273216) ABC transporter RzcB [Rhizob...    76  1e-12
gi|6323217 ATP-binding cassette (ABC) transporter family member;...    76  1e-12
dbj|BAA12015.1| (D83582) metalloprotease transporter [Serratia m...    76  1e-12
pir||T42842 bile salt transport protein, ATP-dependent - rat >gi...    76  1e-12
pir||T42228 P-glycoprotein sister - rat >gi|3273484|gb|AAC24753....    76  1e-12
gi|4502457 ATP-binding cassette, sub-family B (MDR/TAP), member ...    76  1e-12
pir||T31073 multidrug resistance p-glycoprotein - nematode (Haem...    76  1e-12
pir||B72097 dipeptide transporter ATPase - Chlamydophila pneumon...    76  1e-12
gb|AAD28285.1|AF136523_1 (AF136523) bile salt export pump [Homo ...    76  1e-12
emb|CAB88985.1| (AL353864) putative ABC-transport protein. [Stre...    76  1e-12
pir||H82440 ABC transporter, ATP-binding protein VCA0602 [import...    76  1e-12
pir||C83221 transport protein HasD PA3406 [imported] - Pseudomon...    76  1e-12
gi|11430459 ATP-binding cassette, sub-family B (MDR/TAP), member...    76  1e-12
pir||E82879 ABC transporter UU539 [imported] - Ureaplasma urealy...    76  1e-12
gb|AAK42548.1| ABC transporter, ATP binding protein [Sulfolobus ...    75  2e-12
sp|P23174|MDR3_CRIGR MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROT...    75  2e-12
pir||H70788 probable peptidetransport system ABC-transporter ATP...    75  2e-12
pir||JE0248 ATP-binding cassette half-transporter - rat >gi|2982...    75  2e-12
gb|AAD29692.1|AF135793_1 (AF135793) sister of P-glycoprotein [Fu...    75  2e-12
gb|AAD41366.1|AF151698_3 (AF151698) GlnP/GlnQ homolog [Agrobacte...    75  2e-12
pir||H81391 amino-acid ABC transporter ATP-binding protein Cj046...    75  2e-12
gb|AAG26952.1|AC069471_13 (AC069471) P-glycoprotein, putative [A...    75  2e-12
gb|AAG34709.1|AF320001_2 (AF320001) putative ATP binding protein...    75  3e-12
sp|P36372|TAP2_RAT ANTIGEN PEPTIDE TRANSPORTER 2 (APT2) >gi|1119...    75  3e-12
pir||B71077 probable ABC transporter ATP-binding protein - Pyroc...    75  3e-12
gb|AAF65552.1|AF249879_1 (AF249879) liver bile salt export pump ...    75  3e-12
sp|P77279|YBBL_ECOLI HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    75  3e-12
sp|P38053|SSUB_ECOLI PUTATIVE ALIPHATIC SULFONATES TRANSPORT ATP...    75  3e-12
gb|AAC18099.1| (AF058302) ATPase component of putative ABC trans...    75  3e-12
gb|AAC64256.1| (AF042861) putative OppF [Treponema denticola]          75  3e-12
emb|CAB69727.1| (AL137166) putative metal transport ABC transpor...    75  3e-12
gb|AAA93553.1| (L23922) P-glycoprotein 5 [Entamoeba histolytica]       74  4e-12
pir||A49933 proteinase SM transporter PrtD - Serratia marcescens...    74  4e-12
pir||T48672 ABC-type transport system ATP-binding protein hasD [...    74  4e-12
pir||E75120 hypothetical protein PAB1855 - Pyrococcus abyssi (st...    74  4e-12
emb|CAB76006.1| (AL157916) putative ABC transporter, ATP-binding...    74  4e-12
pir||S25577 mt2 protein - rat                                          74  6e-12
gb|AAA50516.1| (M77784) transport protein [Agrobacterium tumefac...    74  6e-12
pir||S38400 mt2 protein - rat >gi|407477|emb|CAA53053.1| (X75305...    74  6e-12
emb|CAA67415.1| (X98917) orf4 [Methanopyrus kandleri]                  74  6e-12
pir||T04251 P-glycoprotein 2 - Arabidopsis thaliana >gi|2108252|...    74  6e-12
pir||T31072 heterocyst differentiation protein HetC - Anabaena s...    74  6e-12
pir||A75083 ATP-binding transport protein PAB1668 - Pyrococcus a...    74  6e-12
pir||D81435 probable iron-uptake ABC transport system ATP-bindin...    74  6e-12
pir||G81168 amino acid ABC transporter, ATP-binding protein NMB0...    74  6e-12
gb|AAF71763.1|AF263912_2 (AF263912) NysG [Streptomyces noursei]        74  6e-12
gb|AAD43626.1|AF071411_1 (AF071411) multidrug resistance protein...    73  7e-12
pir||T46950 probable ATPase component of 2-aminoethylphosphonate...    73  7e-12
pir||T45311 cell division atp-binding protein [imported] - Mycob...    73  7e-12
pir||D69627 cell-division ATP-binding protein ftsE - Bacillus su...    73  7e-12
gb|AAB88659.1| (U62935) multidrug resistance protein 2 [Aspergil...    73  7e-12
pir||T40790 probable permease - fission yeast (Schizosaccharomyc...    73  7e-12
emb|CAB59828.1| (AJ012388) hypothetical protein [Lactococcus lac...    73  7e-12
gb|AAF51223.1| (AE003582) CG9892 gene product [Drosophila melano...    73  7e-12
dbj|BAB05182.1| (AP001512) ABC transporter (ATP-binding protein)...    73  7e-12
dbj|BAB07321.1| (AP001519) cell-division ATP-binding protein [Ba...    73  7e-12
gi|10955056 occP [Agrobacterium tumefaciens] >gi|464298|sp|P3511...    73  1e-11
pir||T30293 ABC transport protein homolog - Salmonella typhi >gi...    73  1e-11
sp|P75831|YBJZ_ECOLI HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    73  1e-11
gi|11038656 ATP-binding cassette, sub-family B, member 11; bile ...    73  1e-11
pir||E81105 ABC transporter, ATP-binding protein NMB1240 [import...    73  1e-11
pir||B81910 probable ABC-transporter ATP-binding protein NMA1409...    73  1e-11
gb|AAF69534.1|AC008007_9 (AC008007) F12M16.17 [Arabidopsis thali...    73  1e-11
prf||1901178A cystic fibrosis transmembrane conductance regulato...    73  1e-11
pir||I76773 ATP binding component of ABC-transporter - Escherich...    73  1e-11
dbj|BAA28332.1| (AB010293) ATP binding component of ABC-transpor...    73  1e-11
emb|CAC05880.1| (AL391754) putative ABC transporter ATP-binding ...    73  1e-11
gb|AAG26946.1|AC069471_7 (AC069471) P-glycoprotein, putative [Ar...    73  1e-11
pir||S30327 multidrug resistance protein 1 - Entamoeba histolyti...    72  2e-11
gb|AAA96713.1| (L42939) major histocompatibility complex class I...    72  2e-11
gi|11498626 ABC transporter, ATP-binding protein [Archaeoglobus ...    72  2e-11
gi|11498589 ABC transporter, ATP-binding protein [Archaeoglobus ...    72  2e-11
pir||T30882 multidrug resistance protein 1 - Aspergillus flavus ...    72  2e-11
pir||T35147 glutamate uptake system ATP-binding protein - Strept...    72  2e-11
pir||G72406 hypothetical protein TM0191 - Thermotoga maritima (s...    72  2e-11
gb|AAF47525.1| (AE003472) CG7955 gene product [alt 3] [Drosophil...    72  2e-11
dbj|BAB04000.1| (AP001508) ABC transporter (ATP-binding protein)...    72  2e-11
pir||D69858 ABC transporter (ATP-binding protein) homolog yknY -...    72  2e-11
pir||S45043 expZ protein - Bacillus subtilis (fragment) >gi|4949...    72  2e-11
pir||T28812 hypothetical protein C54D1.1 - Caenorhabditis elegan...    72  2e-11
sp|P39115|EXPZ_BACSU NUCLEOTIDE BINDING PROTEIN EXPZ >gi|7445764...    72  2e-11
gb|AAD15830.1| (AF062387) TAP2 protein [Xenopus laevis]                72  2e-11
gb|AAD49436.1|AF083642_1 (AF083642) P-glycoprotein [Onchocerca v...    72  2e-11
pir||G75548 ABC transporter, ATP-binding protein - Deinococcus r...    72  2e-11
gb|AAF48177.1| (AE003489) CG1824 gene product [Drosophila melano...    72  2e-11
sp|P36637|SAPF_ECOLI PEPTIDE TRANSPORT SYSTEM ATP-BINDING PROTEI...    71  3e-11
sp|Q60350|Y035_METJA HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    71  3e-11
pir||H71302 probable ABC transporter, ATP-binding protein - syph...    71  3e-11
gi|10956101 ABC transporter subunit PenL [Pediococcus pentosaceu...    71  3e-11
gb|AAF55241.1| (AE003710) CG4225 gene product [Drosophila melano...    71  3e-11
pir||E81936 probable amino acid permease ATP-binding protein NMA...    71  3e-11
dbj|BAB05744.1| (AP001514) ABC transporter (ATP-binding protein)...    71  3e-11
sp|Q00748|MDR5_DROME MULTIDRUG RESISTANCE PROTEIN HOMOLOG 65 (P-...    71  4e-11
sp|P36371|TAP2_MOUSE ANTIGEN PEPTIDE TRANSPORTER 2 (APT2) (HISTO...    71  4e-11
pir||T30855 multidrug resistance protein 2 - fluke (Schistosoma ...    71  4e-11
sp|Q61102|ABC7_MOUSE ATP-BINDING CASSETTE, SUB-FAMILY B, MEMBER ...    71  4e-11
gb|AAB41968.1| (U60091) TAP2 [Mus musculus castaneus]                  71  4e-11
gb|AAB41969.1| (U60092) TAP2 [Mus musculus castaneus]                  71  4e-11
gb|AAB41970.1| (U60087) TAP2 [Mus musculus]                            71  4e-11
gb|AAB41971.1| (U60088) TAP2 [Mus musculus]                            71  4e-11
gb|AAB41972.1| (U60089) TAP2 [Mus musculus]                            71  4e-11
gi|7549791 ATP-binding cassette, sub-family B, member 3; ATP dep...    71  4e-11
sp|P54718|YFIB_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    71  4e-11
pir||E69771 ABC transporter (ATP-binding protein) homolog ydbJ -...    71  4e-11
gb|AAF50669.1| (AE003563) Mdr65 gene product [Drosophila melanog...    71  4e-11
gb|AAG32538.1| (AY005472) SalT [Streptococcus salivarius]              71  4e-11
emb|CAA08835.1| (AJ009799) ABC transporter protein [Gallus gallus]     71  5e-11
emb|CAB37661.1| (AJ224479) cdd4-like protein [Bacillus sphaericus]     71  5e-11
dbj|BAA96370.1| (AB035331) ABC protein [Physarum polycephalum]         71  5e-11
pir||DVHY1C multidrug resistance protein 1 - Chinese hamster >gi...    70  6e-11
sp|P21448|MDR1_CRIGR MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROT...    70  6e-11
gb|AAA37005.1| (M59254) p-glycoprotein [Cricetulus sp.]                70  6e-11
sp|P75790|YBIT_ECOLI HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PR...    70  6e-11
gi|11497838 branched-chain amino acid ABC transporter, ATP-bindi...    70  6e-11
pir||B71676 probable ABC transporter msbA2 - Rickettsia prowazek...    70  6e-11
pir||T21266 hypothetical protein F22E10.1 - Caenorhabditis elega...    70  6e-11
pir||E75302 ABC transporter, ATP-binding protein - Deinococcus r...    70  6e-11
emb|CAA57938.1| (X82612) ATM1 [Saccharomyces cerevisiae]               70  8e-11
gi|6323959 mitochondrial ABC transporter protein; Atm1p [Sacchar...    70  8e-11
gb|AAB63643.1| (AC001645) ABC transporter (PDR5-like) isolog [Ar...    70  8e-11
gb|AAC98048.1| (AC005896) putative ABC transporter [Arabidopsis ...    70  8e-11
pir||G72598 probable ABC transporter ATP-binding protein APE1255...    70  8e-11
gb|AAD47141.1|AF078777_1 (AF078777) ABC transporter [Homo sapiens]     70  8e-11
pir||D83419 probable ATP-binding component of ABC transporter PA...    70  8e-11

>pir||F75107 abc transporter, ATP-binding protein PAB1929 - Pyrococcus abyssi
           (strain Orsay) >gi|5458086|emb|CAB49575.1| (AJ248285)
           ABC TRANSPORTER, ATP-BINDING PROTEIN [Pyrococcus abyssi]
           Length = 633
           
 Score = 1281 bits (3278), Expect = 0.0
 Identities = 633/633 (100%), Positives = 633/633 (100%)

Query: 1   MIIRGKVRESKIPKFKHRWFGVLEVESSEGEVYRLYMSGVAQWFIEGDEVEIKVINEPKE 60
           MIIRGKVRESKIPKFKHRWFGVLEVESSEGEVYRLYMSGVAQWFIEGDEVEIKVINEPKE
Sbjct: 1   MIIRGKVRESKIPKFKHRWFGVLEVESSEGEVYRLYMSGVAQWFIEGDEVEIKVINEPKE 60

Query: 61  KDGVKVLEFNDYELYKFYNGEKIKVWPLWEKIYKAKRYSPLTGDVLYEYEIRAREATYES 120
           KDGVKVLEFNDYELYKFYNGEKIKVWPLWEKIYKAKRYSPLTGDVLYEYEIRAREATYES
Sbjct: 61  KDGVKVLEFNDYELYKFYNGEKIKVWPLWEKIYKAKRYSPLTGDVLYEYEIRAREATYES 120

Query: 121 DFEFIAELEQYHYASQKEKVALWRCEKCGTIIEANTKPICPKCKTDKHVHILEIKGSTPA 180
           DFEFIAELEQYHYASQKEKVALWRCEKCGTIIEANTKPICPKCKTDKHVHILEIKGSTPA
Sbjct: 121 DFEFIAELEQYHYASQKEKVALWRCEKCGTIIEANTKPICPKCKTDKHVHILEIKGSTPA 180

Query: 181 SRFLILELVKREEYEPRILAYVRIDPPIPLMHRKLPNGEIERNIREKVFPEDWLKPSFWP 240
           SRFLILELVKREEYEPRILAYVRIDPPIPLMHRKLPNGEIERNIREKVFPEDWLKPSFWP
Sbjct: 181 SRFLILELVKREEYEPRILAYVRIDPPIPLMHRKLPNGEIERNIREKVFPEDWLKPSFWP 240

Query: 241 EKIMHELFMELRKKYSKKVARSLLWEKAKEKALRESNTAGARIARVVVHPDYRSDGLGQL 300
           EKIMHELFMELRKKYSKKVARSLLWEKAKEKALRESNTAGARIARVVVHPDYRSDGLGQL
Sbjct: 241 EKIMHELFMELRKKYSKKVARSLLWEKAKEKALRESNTAGARIARVVVHPDYRSDGLGQL 300

Query: 301 SVKAALEWVSERRIPEMRKKKHFVETIAQMARYNPFFEKVGFKFVWETASGRPVLIYPLT 360
           SVKAALEWVSERRIPEMRKKKHFVETIAQMARYNPFFEKVGFKFVWETASGRPVLIYPLT
Sbjct: 301 SVKAALEWVSERRIPEMRKKKHFVETIAQMARYNPFFEKVGFKFVWETASGRPVLIYPLT 360

Query: 361 QEAKEYLERYFKEDPYAPKEPLWKPSYGKVEMLEGPIVFKNVTKVFESELDIKGLPQEIQ 420
           QEAKEYLERYFKEDPYAPKEPLWKPSYGKVEMLEGPIVFKNVTKVFESELDIKGLPQEIQ
Sbjct: 361 QEAKEYLERYFKEDPYAPKEPLWKPSYGKVEMLEGPIVFKNVTKVFESELDIKGLPQEIQ 420

Query: 421 DLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKY 480
           DLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKY
Sbjct: 421 DLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKY 480

Query: 481 RPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLNRAGLSDAVL 540
           RPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLNRAGLSDAVL
Sbjct: 481 RPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLNRAGLSDAVL 540

Query: 541 YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGIT 600
           YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGIT
Sbjct: 541 YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGIT 600

Query: 601 AVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
           AVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL
Sbjct: 601 AVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633


>pir||G71026 hypothetical protein PH1507 - Pyrococcus horikoshii
           >gi|3257932|dbj|BAA30615.1| (AP000006) 633aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 633
           
 Score = 1244 bits (3183), Expect = 0.0
 Identities = 600/633 (94%), Positives = 627/633 (98%)

Query: 1   MIIRGKVRESKIPKFKHRWFGVLEVESSEGEVYRLYMSGVAQWFIEGDEVEIKVINEPKE 60
           MII+GKV+ESKIPKFKHRWFGVLEVE+SEGEVYRLYMSGVAQWFIEGDEVEI+VINEPKE
Sbjct: 1   MIIKGKVKESKIPKFKHRWFGVLEVETSEGEVYRLYMSGVAQWFIEGDEVEIRVINEPKE 60

Query: 61  KDGVKVLEFNDYELYKFYNGEKIKVWPLWEKIYKAKRYSPLTGDVLYEYEIRAREATYES 120
           KDGVK+LEFNDYELYKFYNGEKIKVWPLWEKIY+AKRYSPLTG+VLYEYEIRAREATYES
Sbjct: 61  KDGVKILEFNDYELYKFYNGEKIKVWPLWEKIYRAKRYSPLTGEVLYEYEIRAREATYES 120

Query: 121 DFEFIAELEQYHYASQKEKVALWRCEKCGTIIEANTKPICPKCKTDKHVHILEIKGSTPA 180
           DFEFIAELEQYHYASQKEKVALWRCEKCGTIIEANTKPICPKCKTDKHVHILEIKGSTPA
Sbjct: 121 DFEFIAELEQYHYASQKEKVALWRCEKCGTIIEANTKPICPKCKTDKHVHILEIKGSTPA 180

Query: 181 SRFLILELVKREEYEPRILAYVRIDPPIPLMHRKLPNGEIERNIREKVFPEDWLKPSFWP 240
           SRFLILELVKREEYEPRILAYVR+DPPIPLMHRKLPNGE+ERNIREKVFPEDWLKPSFWP
Sbjct: 181 SRFLILELVKREEYEPRILAYVRVDPPIPLMHRKLPNGEVERNIREKVFPEDWLKPSFWP 240

Query: 241 EKIMHELFMELRKKYSKKVARSLLWEKAKEKALRESNTAGARIARVVVHPDYRSDGLGQL 300
           EKIMHELFMELRKKY KK+ARSLLWE+AKE+ALRESNTAGARIARVVVHPDYRSDG+GQL
Sbjct: 241 EKIMHELFMELRKKYPKKIARSLLWEEAKERALRESNTAGARIARVVVHPDYRSDGIGQL 300

Query: 301 SVKAALEWVSERRIPEMRKKKHFVETIAQMARYNPFFEKVGFKFVWETASGRPVLIYPLT 360
           SVKAALEW++ERRIPEMRK+KHFVETIAQMARYNPFFEKVGFKFVWETASGRPVL+YPLT
Sbjct: 301 SVKAALEWIAERRIPEMRKRKHFVETIAQMARYNPFFEKVGFKFVWETASGRPVLMYPLT 360

Query: 361 QEAKEYLERYFKEDPYAPKEPLWKPSYGKVEMLEGPIVFKNVTKVFESELDIKGLPQEIQ 420
           QEAKEYL+RYF+EDPYAPKEPLWKPSYGKVE LEGPIVFKNVTKVFESELDIKGLP+EIQ
Sbjct: 361 QEAKEYLDRYFREDPYAPKEPLWKPSYGKVEKLEGPIVFKNVTKVFESELDIKGLPEEIQ 420

Query: 421 DLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKY 480
           DLLKAFGVRHRVIQRPVLRNLNF INPGE+VAVVGASGAGKTTLLRLILGAI+GYWEEKY
Sbjct: 421 DLLKAFGVRHRVIQRPVLRNLNFQINPGEIVAVVGASGAGKTTLLRLILGAIRGYWEEKY 480

Query: 481 RPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLNRAGLSDAVL 540
           RPTSGKIEVPKNAKVS LIPGE+EPEFGSETILEHVYRK+RDLNAAVE+LNR+GLSDAVL
Sbjct: 481 RPTSGKIEVPKNAKVSALIPGEMEPEFGSETILEHVYRKVRDLNAAVEILNRSGLSDAVL 540

Query: 541 YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGIT 600
           YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEI REAGIT
Sbjct: 541 YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIAREAGIT 600

Query: 601 AVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
           A+IITHRPEVVKALDPDKVLFVGYGTVIVR SL
Sbjct: 601 AIIITHRPEVVKALDPDKVLFVGYGTVIVRDSL 633


>gi|11498669 ABC transporter, ATP-binding protein, putative [Archaeoglobus
           fulgidus] >gi|7445782|pir||H69382 ABC transporter,
           ATP-binding protein homolog - Archaeoglobus fulgidus
           >gi|2649523|gb|AAB90175.1| (AE001029) ABC transporter,
           ATP-binding protein, putative [Archaeoglobus fulgidus]
           Length = 620
           
 Score =  725 bits (1852), Expect = 0.0
 Identities = 355/624 (56%), Positives = 482/624 (76%), Gaps = 13/624 (2%)

Query: 6   KVRESKIPKFKHRWFGVLEVESSEGEVYRLYMSGVAQWFIEGDEVEIKVINEPKEKDGVK 65
           KV   ++PK +HRWFG +E+++       LYMSG+A W  EGD VE+ + NEPKE  G K
Sbjct: 4   KVVSHELPKHRHRWFGAVELDNG----LTLYMSGIAAWLFEGDVVEVVIKNEPKEIYGRK 59

Query: 66  VLEFNDYELYKFYNGEKIKVWPLWEKIYKAKRYSPLTGDVLYEYEIRAREATYESDFEFI 125
           +L F DYELYKFY  E+IKVW ++ +  +  RYS   G  +Y Y IRAREA YE DFE I
Sbjct: 60  ILFFADYELYKFYGSERIKVWDVFSRNLELPRYS--FGKEVYRYRIRAREAVYEKDFERI 117

Query: 126 AELEQYHYASQKEKVALWRCEKCGTIIEANTKPICPKCKTDKHVHILEIKGSTPASRFLI 185
           AELEQYHYASQK KVALW+C  CG +IEANTKP+C +C + ++VHI+EIKGSTPASRFLI
Sbjct: 118 AELEQYHYASQKSKVALWKCYDCGNLIEANTKPVC-ECGS-RNVHIVEIKGSTPASRFLI 175

Query: 186 LELVKREEYEPRILAYVRIDPPIPLMHRKLPNGEIERNIREKVFPEDWLKPSFWPEKIMH 245
            ELV+R+ +EP ++AYVR+DPP+PLMHRKL +G+I  NIRE+VFP++W +  F PEK + 
Sbjct: 176 FELVERQPFEPEVVAYVRVDPPVPLMHRKL-DGKIVENIRERVFPKEWFENVFSPEKELS 234

Query: 246 ELFMELRKKYSKKVARSLLWEKAKEKALRESNTAGARIARVVVHPDYRSDGLGQLSVKAA 305
           ELF +LR ++S KVAR  LWE+A E+A+++ N+A +RIARVVVHPDYR+DGLG L+V+ A
Sbjct: 235 ELFRKLRSRFSLKVARHRLWEEASEEAMKKCNSAASRIARVVVHPDYRADGLGILAVRTA 294

Query: 306 LEWVSERRIPEMRKKKHFVETIAQMARYNPFFEKVGFKFVWETASGRPVLIYPLTQEAKE 365
           +EW+ ERR+PEMR +KH VETIAQMAR+NPFFEK GF ++W+TASG+PVL  PL++EA+ 
Sbjct: 295 VEWIEERRVPEMRMRKHLVETIAQMARFNPFFEKAGFYYLWDTASGKPVLYKPLSEEAER 354

Query: 366 YLERYFKEDPYAPKE--PLWKPSYGKVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLL 423
           Y+ ++ +ED  A      L    YG V+ LE  + F+NV+K+F S LD++ +  E++ +L
Sbjct: 355 YIRKFLEEDEVARGHGGKLCVSRYGSVKPLE-KLKFRNVSKLFASTLDLEKVSDEVRTVL 413

Query: 424 KAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPT 483
           ++FGVR RV++R VLR++N  I PGE+VAVVGASG+GKTT LRLI+G      ++ Y+P+
Sbjct: 414 ESFGVRQRVVERYVLRDVNLEIKPGEIVAVVGASGSGKTTFLRLIVGEALKLDDDVYKPS 473

Query: 484 SGKIEVPKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLNRAGLSDAVLYRA 543
           SG +EV  ++ ++ +IP E+EP+   ++ILE ++    D++ AVEVLNRAG+SDAVLYRA
Sbjct: 474 SGMVEVVVDS-IAAMIPSELEPQITEKSILEQIFDITGDIHLAVEVLNRAGISDAVLYRA 532

Query: 544 KFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVI 603
           +F+ELSTGQKER K+A+ LA++P+++L+DEFAAHLD +TA+RVARK+SE+ REA IT + 
Sbjct: 533 RFNELSTGQKERFKLAACLAKKPSLMLVDEFAAHLDEMTAVRVARKISELAREAKITLIA 592

Query: 604 ITHRPEVVKALDPDKVLFVGYGTV 627
           +THR EV+ AL PD++L+VGYG V
Sbjct: 593 VTHRKEVINALSPDRILYVGYGGV 616


>pir||D72453 hypothetical protein APE2272 - Aeropyrum pernix (strain K1)
           >gi|5105973|dbj|BAA81284.1| (AP000064) 660aa long
           hypothetical protein [Aeropyrum pernix]
           Length = 660
           
 Score =  686 bits (1752), Expect = 0.0
 Identities = 337/635 (53%), Positives = 450/635 (70%), Gaps = 15/635 (2%)

Query: 4   RGKVRESKIPKFKHRWFGVLEVESSEGEVYRLYMSGVAQWFIEGDEVEIKVINEPKEKDG 63
           + KV   +IP+   RW G L VE   G ++     G+A+WF  G+ VE+++  EP++ DG
Sbjct: 16  KAKVIGQRIPRVGWRWLGGLTVEHEGGRLHLFMTGGIARWFSPGETVELELHEEPEDIDG 75

Query: 64  VKVLEFNDYELYKFYNGEKIKVWPLWEKIYKAKRYSPLTGDVLYEYEIRAREATYESDFE 123
           V V     Y L++ Y GE++ VWP+W K+    R + +TG  +Y Y + AREA  E D++
Sbjct: 76  VMVAPRESYRLWRIYRGERVLVWPVWRKVVSIDRET-ITGRRVYSYRLLAREAQTEEDYK 134

Query: 124 FIAELEQYHYASQKEKVALWRCEKCGTIIEANTKPICPKCKTDKHVHILEIKGSTPASRF 183
            I  LEQYHYAS++E VA+WRC  CG  +E+N +P CP+      + + EI+GS P+SRF
Sbjct: 135 EIVGLEQYHYASKEEIVAIWRCPVCGVYLESNLQPECPRDGVP--MKLQEIRGSLPSSRF 192

Query: 184 LILELVKREEYEPRILAYVRIDPPIPLMHRKLPNGE----IERNIREKVFPEDWLKPSFW 239
           +++EL+ R+ YEPRI+ YVR+D PIPLMHR++P       +E+ IREKVFP+ W  P+FW
Sbjct: 193 MVVELLDRKPYEPRIVGYVRVDTPIPLMHRRVPKPGGGFGVEKMIREKVFPKYWFHPTFW 252

Query: 240 P-----EKIMHELFMELRKKY-SKKVARSLLWEKAKEKALRESNTAGARIARVVVHPDYR 293
           P      + +   F EL K Y S+++AR+ + E+  ++ALR +NTA ARIARVVVHPDYR
Sbjct: 253 PVEPRNRRSLLARFRELAKLYGSRRIARAAVGEEIADEALRRANTAAARIARVVVHPDYR 312

Query: 294 SDGLGQLSVKAALEWVSERRIPEMRKKKHFVETIAQMARYNPFFEKVGFKFVWETASGRP 353
            DGLG  SV  ALEW+ ERRIPEMR+ KH VETIAQMARYNPFFE+ GFK++W+TASGRP
Sbjct: 313 GDGLGVASVSLALEWIRERRIPEMRRAKHVVETIAQMARYNPFFERAGFKYMWDTASGRP 372

Query: 354 VLIYPLTQEAKEYLERYFKEDPYAPKEP--LWKPSYGKVEMLEGPIVFKNVTKVFESELD 411
           VL++PLT+EA+  +E++   DP A      L++P Y  VEML  P     VTK + S LD
Sbjct: 373 VLMHPLTEEARRIIEKFLSSDPVAKSHGGVLYRPRYSPVEMLSEPESLVGVTKSYRSVLD 432

Query: 412 IKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGA 471
           I+ LP+E+QD+L+AFG   RV++R VL+++N T+NPG V AVVGASGAGKTTLLR+ILG 
Sbjct: 433 IERLPRELQDVLRAFGAERRVVERYVLKDVNITVNPGSVAAVVGASGAGKTTLLRMILGK 492

Query: 472 IKGYWEEKYRPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLN 531
             G   E YRP SG +++P N K + L+PGE+EP FG ET+LEHV  K+ D  AAVEVL+
Sbjct: 493 ALGIGGEGYRPDSGVVKIPTNTKAAALLPGELEPSFGGETLLEHVASKLGDPGAAVEVLS 552

Query: 532 RAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVS 591
             GL DA+ +RA F ELSTGQKERAK+ASLLAERPN+L+IDEF AHLD LTA R+ARK+ 
Sbjct: 553 SVGLGDAIFFRASFGELSTGQKERAKLASLLAERPNLLVIDEFMAHLDPLTARRIARKLG 612

Query: 592 EIVREAGITAVIITHRPEVVKALDPDKVLFVGYGT 626
           ++ R  GIT ++ T+RPE++ AL PD V+ VGYG+
Sbjct: 613 KLARSKGITLIVSTNRPEILDALQPDTVILVGYGS 647


>sp|O34900|YTMN_BACSU PROBABLE AMINO-ACID ABC TRANSPORTER ATP-BINDING PROTEIN YTMN
           >gi|7442519|pir||F69641 histidine transport protein hisP
           - Bacillus subtilis >gi|2293251|gb|AAC00329.1|
           (AF008220) putative amino acid transporter [Bacillus
           subtilis] >gi|2635399|emb|CAB14894.1| (Z99118) histidine
           transport protein (ATP-binding protein) [Bacillus
           subtilis] >gi|2635418|emb|CAB14912.1| (Z99119) histidine
           transport protein (ATP-binding protein) [Bacillus
           subtilis]
           Length = 259
           
 Score = 93.2 bits (228), Expect = 8e-18
 Identities = 76/235 (32%), Positives = 115/235 (48%), Gaps = 43/235 (18%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           EI+++ K FG+ H      VL+ +N T+  GEVV ++G SG+GKTT LR +         
Sbjct: 3   EIKNIHKQFGIHH------VLKGINLTVRKGEVVTIIGPSGSGKTTFLRCL--------N 48

Query: 478 EKYRPTSGKIEVPKNAKVSVLIPGEIEPE---------------FGSETILEHVY----- 517
              RP  G I +  +  ++   P + E                 F  +T++E+V      
Sbjct: 49  LLERPDEGIISI-HDKVINCRFPSKKEVHWLRKQTAMVFQQYHLFAHKTVIENVMEGLTI 107

Query: 518 -RKIRDLNA---AVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDE 573
            RK+R  +A   A   L + GL D +   A  S+LS GQK+R  IA  LA  P+VLL DE
Sbjct: 108 ARKMRKQDAYAVAENELRKVGLQDKL--NAYPSQLSGGQKQRVGIARALAIHPDVLLFDE 165

Query: 574 FAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
             A LD      V   + EIV+  G T +++TH  E  + +  D+V+F+  G ++
Sbjct: 166 PTAALDPELVGEVLEVMLEIVK-TGATMIVVTHEMEFARRVS-DQVVFMDEGVIV 218


>emb|CAA11724.1| (AJ223978) putative ABC transporter, YvrO [Bacillus subtilis]
           Length = 229
           
 Score = 88.2 bits (215), Expect = 3e-16
 Identities = 70/218 (32%), Positives = 112/218 (51%), Gaps = 40/218 (18%)

Query: 436 PVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSG-----KIEVP 490
           P+L+++N T+  GE +A++G SG+GK+TL+ +I G +        RPTSG     +I++ 
Sbjct: 19  PILKHINLTVQAGEFLAIMGPSGSGKSTLMNII-GCLD-------RPTSGTYTLDQIDIL 70

Query: 491 KNAKVSVLIPGEIEPE---FGSETI-------------LEHVYRKIRDLNA---AVEVLN 531
           K    ++    EI  E   F  +T              L  +Y K++       A E L 
Sbjct: 71  KGKDGAL---AEIRNESIGFVFQTFHLLPRLTALQNVELPMIYNKVKKKERRQRAYEALE 127

Query: 532 RAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVS 591
           + GL D V Y+    +LS GQK+R  IA  L  +P  +L DE    LDT ++ ++    S
Sbjct: 128 KVGLKDRVSYKPP--KLSGGQKQRVAIARALVNQPRFILADEPTGALDTKSSEQILALFS 185

Query: 592 EIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIV 629
           E+ RE G T ++ITH P+V K    D+ +F+  G +++
Sbjct: 186 ELHRE-GKTIIMITHDPDVAK--KADRTVFIRDGELVL 220


>pir||C82957 probable ATP-binding component of ABC transporter PA5503 [imported]
           - Pseudomonas aeruginosa (strain PAO1)
           >gi|9951839|gb|AAG08888.1|AE004963_1 (AE004963) probable
           ATP-binding component of ABC transporter [Pseudomonas
           aeruginosa]
           Length = 335
           
 Score = 87.4 bits (213), Expect = 4e-16
 Identities = 77/233 (33%), Positives = 118/233 (50%), Gaps = 36/233 (15%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E  D+ K + V  R I  P L+     I  G++  ++G SGAGK+TLLRLI         
Sbjct: 3   EFHDVHKTYRVAGREI--PALQPTRLNIQAGQIFGLIGHSGAGKSTLLRLI--------N 52

Query: 478 EKYRPTSGKIEVPKNAKVSVLIP----------GEIEPEFG---SETILEHVYRKIR--- 521
               P+ G+I V +   V+ L            G I   F    S+T+ +++   +R   
Sbjct: 53  RLEEPSGGRILV-EGEDVTALDAEGLRRFRQRVGMIFQHFNLLSSKTVADNIAMPLRLAG 111

Query: 522 -----DLNAAV-EVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFA 575
                +++A V E+L R GLSD    R   ++LS GQK+R  IA  LA RP++LL DE  
Sbjct: 112 GFSRAEVDARVSELLARVGLSDHA--RKYPAQLSGGQKQRVGIARALACRPSILLCDEAT 169

Query: 576 AHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
           + LD  T   V + ++EI RE  +T V+ITH  +V++ +  D+V  +  G ++
Sbjct: 170 SALDPQTTASVLQLLAEINRELKLTIVLITHEMDVIRRV-CDQVAVMDGGAIV 221


>dbj|BAA76299.1| (AB003329) LAMDR1 [Leishmania amazonensis]
           Length = 1341
           
 Score = 87.0 bits (212), Expect = 6e-16
 Identities = 68/244 (27%), Positives = 121/244 (48%), Gaps = 37/244 (15%)

Query: 398 VFKNVTKVFESELDIKGLPQE-IQDLLKAFGVRHRVIQRP---VLRNLNFTINPGEVVAV 453
           +FK + +V   ++D  G+P    +  ++   VR     RP   + R+LN TI  G+ VA 
Sbjct: 426 IFKTIERVPPVDIDAGGVPVTGFRQSIEFHNVRFSYPTRPDMILFRDLNLTIKRGQKVAF 485

Query: 454 VGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVP---------KNAKVSVLIPGEIE 504
            G+SG GK++++ LI        +  Y P  G +             + +  + I  + E
Sbjct: 486 SGSSGCGKSSMIGLI--------QRFYDPVGGAVLCDGVDMRELCLYDWRDQIGIVSQ-E 536

Query: 505 PEFGSETILEHVYRKIRDLNA----AVEVLNRAGLSDAVL---------YRAKFSELSTG 551
           P   + T++E+V  ++   NA     +E   +A + D ++           A  S+LS G
Sbjct: 537 PNLFAGTMMENV--RVGKPNATEEEVIEACRQANVHDTIMSLPDQYNTPVGAVGSQLSGG 594

Query: 552 QKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVV 611
           QK+R  IA  L +RP +LL+DE  + LD  + M V R + +++++ G+T ++I HR E +
Sbjct: 595 QKQRIAIARALVKRPPILLLDEATSALDRKSEMEVQRSLDQLMQKGGMTVIVIAHRLETI 654

Query: 612 KALD 615
           + +D
Sbjct: 655 RNVD 658


>pir||H82709 colicin V secretion ABC transporter ATP-binding protein XF1220
           [imported] - Xylella fastidiosa (strain 9a5c)
           >gi|9106194|gb|AAF84030.1|AE003955_11 (AE003955) colicin
           V secretion ABC transporter ATP-binding protein [Xylella
           fastidiosa]
           Length = 707
           
 Score = 86.2 bits (210), Expect = 1e-15
 Identities = 71/245 (28%), Positives = 117/245 (46%), Gaps = 44/245 (17%)

Query: 409 ELDIKGLPQEIQDL-LKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRL 467
           EL    LP++  D+ ++    R+   +  VL++ +F +  GE VA++GASG GKTTL++L
Sbjct: 459 ELPEMQLPKKEPDIEVEGLSFRYGEDEPWVLKDCSFKVAAGESVAIIGASGCGKTTLMKL 518

Query: 468 ILGAIKGYWEEKYRPTSGKIEVP---------KNAKVSV--------LIPGEI------- 503
           +LG +K        PT+G I +          +N +  V        L  G +       
Sbjct: 519 LLGLLK--------PTAGTIRISGRDLHKFGTRNVRSIVGAVMQDDQLFAGSVADNISFF 570

Query: 504 EPEFGSETILEHVYRKIRDLNAAVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLA 563
           +P+F  E I          L A  E +    +    L     S LS GQK+R  +A  L 
Sbjct: 571 DPDFDLERI-----EAAAKLAAIHEDIAAMPMGYHALIGDMGSALSGGQKQRVILARALY 625

Query: 564 ERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVG 623
            +P +L +DE  +HLD +      R V++ V +  +T VI+ HRPE + +   D+V+ + 
Sbjct: 626 RQPKLLFLDEATSHLDVMR----ERLVNDAVHQLKLTKVIVAHRPETIAS--TDRVVILD 679

Query: 624 YGTVI 628
           +G ++
Sbjct: 680 HGRIV 684


>emb|CAB61549.1| (AL133171) putative ABC transporter [Streptomyces coelicolor A3(2)]
           Length = 740
           
 Score = 84.7 bits (206), Expect = 3e-15
 Identities = 68/226 (30%), Positives = 117/226 (51%), Gaps = 25/226 (11%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E+Q++  +FG  +  + +P+L   + T+ PG+ VA+VG SG+GK+T+ RLI G +   W+
Sbjct: 507 ELQNV--SFG--YNPLDKPLLSGFDLTVGPGQQVALVGGSGSGKSTVSRLISG-LYASWD 561

Query: 478 EKYRPTSGKI-EVPKNAKVSVLIPGEIEPEFGSETILEHVY---RKIRDLNAAVEVLNRA 533
              R    ++ ++P+ A  S +   + +      ++ ++V      I D +A VE L  A
Sbjct: 562 GVIRIDGQRLDDIPRGALASSVSFVDQDVFLFEGSVRDNVALWDPSIPD-DAVVEALKDA 620

Query: 534 GLSDAVLYR---------AKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAM 584
            L D V  R               S GQ++R +IA  L  RP++L++DE  + LD  T +
Sbjct: 621 ALYDVVTRRPGGLHSPVEQDGRNFSGGQRQRLEIARALVRRPSILVLDEVTSALDAETEL 680

Query: 585 RVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVR 630
                V + +R  G   V+I HR   V+  D D+++ + +GTV+ R
Sbjct: 681 ----VVMDNLRRRGCACVVIAHRLSTVR--DSDEIVVLDHGTVVER 720


>pir||F71800 ABC transporter, ATP-binding protein - Helicobacter pylori  (strain
           J99) >gi|4156118|gb|AAD07069.1| (AE001570) abc
           transporter, ATP-binding protein [Helicobacter pylori
           J99]
           Length = 327
           
 Score = 84.3 bits (205), Expect = 4e-15
 Identities = 68/216 (31%), Positives = 110/216 (50%), Gaps = 31/216 (14%)

Query: 438 LRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEV-------- 489
           L+ +N  +  G+++ V+G SGAGK+TL+RLI            RP+SG++ V        
Sbjct: 19  LKGVNLELKKGDILGVIGYSGAGKSTLIRLI--------NCLERPSSGEVLVNGVNLLNL 70

Query: 490 -PKNAKVSVLIPGEIEPEFG---SETILEHV--------YRKIRDLNAAVEVLNRAGLSD 537
            PK  + +    G I   F    ++ + E+V        + K +  +   E+L   GL D
Sbjct: 71  KPKELQKARQKIGMIFQHFNLLSAKNVFENVAFALEIARWEKTKIKSRVHELLELVGLED 130

Query: 538 AVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREA 597
            V +  K  +LS GQK+R  IA  LA  PN+LL DE  + LD+ T   +   +S I ++ 
Sbjct: 131 KVHFYPK--QLSGGQKQRVAIARSLANCPNLLLCDEATSALDSKTTHSILTLLSGIQKKF 188

Query: 598 GITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
            ++ V ITH+ EVVK L  +++  +  G ++ R S+
Sbjct: 189 DLSIVFITHQIEVVKEL-CNQMCVISSGEIVERGSV 223


>emb|CAB69672.1| (AL137165) probable ABC transporter protein, ATP-binding component.
           [Streptomyces coelicolor A3(2)]
           Length = 589
           
 Score = 84.3 bits (205), Expect = 4e-15
 Identities = 63/213 (29%), Positives = 106/213 (49%), Gaps = 33/213 (15%)

Query: 435 RPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKN-- 492
           RP + +   ++ PGE +A+VGASGAGK+T+L L++G +        RPTSG++ +  +  
Sbjct: 365 RPAVSDFTLSVEPGETIALVGASGAGKSTVLNLVIGFL--------RPTSGRLLLDGHDM 416

Query: 493 ---------------AKVSVLIPGEIEPE--FGSETILEHVYR-KIRDLNAAVEVLNRAG 534
                           + S+L  G I     +G +   E   R  +RD N A+E ++R  
Sbjct: 417 NTLDLRTYRRFVSVVPQESILFDGTIRENVAYGMDEADEETVRGALRDAN-ALEFVDRLP 475

Query: 535 LSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIV 594
                L     + LS GQ++R  IA  L   P VL++DE  + LDT +   V + ++ ++
Sbjct: 476 RGLDTLVGEHGARLSGGQRQRLAIARALIRDPRVLVLDEATSALDTRSEALVQQALARLL 535

Query: 595 REAGITAVIITHRPEVVKALDPDKVLFVGYGTV 627
           R  G T  ++ HR   V+    D+++ +G G +
Sbjct: 536 R--GRTTFVVAHRLSTVRG--ADRIVVMGEGRI 564


>gb|AAC45666.1| (AF010307) AbcC [Helicobacter pylori]
           Length = 327
           
 Score = 83.9 bits (204), Expect = 5e-15
 Identities = 68/216 (31%), Positives = 110/216 (50%), Gaps = 31/216 (14%)

Query: 438 LRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEV-------- 489
           L+ +N  +  G+++ V+G SGAGK+TL+RLI            RP+SG++ V        
Sbjct: 19  LKGVNLELKKGDILGVIGYSGAGKSTLIRLI--------NCLERPSSGEVLVNGVNLLKL 70

Query: 490 -PKNAKVSVLIPGEIEPEFG---SETILEHV--------YRKIRDLNAAVEVLNRAGLSD 537
            PK  + +    G I   F    ++ + E+V        + K +  +   E+L   GL D
Sbjct: 71  KPKELQKARQKIGMIFQHFNLLSAKDVFENVAFALEIARWEKTKIKSRVHELLELVGLED 130

Query: 538 AVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREA 597
            V +  K  +LS GQKER  IA  LA  P++LL DE  + LD+ T   +   +S I ++ 
Sbjct: 131 KVHFYPK--QLSGGQKERVAIARSLANCPDLLLCDEATSALDSKTTHSILTLLSGIQKKL 188

Query: 598 GITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
            ++ V ITH+ EVVK L  +++  +  G ++ R S+
Sbjct: 189 DLSVVFITHQIEVVKEL-CNQMCVISSGEIVERGSV 223


>sp|P44785|ABC_HAEIN ATP-BINDING PROTEIN ABC >gi|1073885|pir||C64082 ATP-binding protein
           homolog HI0621 - Haemophilus influenzae  (strain Rd
           KW20) >gi|1573615|gb|AAC22280.1| (U32744) ABC
           transporter, ATP-binding protein [Haemophilus influenzae
           Rd]
           Length = 345
           
 Score = 83.9 bits (204), Expect = 5e-15
 Identities = 70/211 (33%), Positives = 103/211 (48%), Gaps = 31/211 (14%)

Query: 438 LRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKI-----EVPKN 492
           L N++  I  G++  V+GASGAGK+TL+R +            +PTSG +     E+ K 
Sbjct: 21  LDNVSLNIEKGQICGVIGASGAGKSTLIRCV--------NLLEKPTSGSVIVDGVELTKL 72

Query: 493 AKVSVLIP----GEIEPEFG---SETILEHVY--------RKIRDLNAAVEVLNRAGLSD 537
           +   +++     G I   F    S T+ E+V          K +       +L+  GLS+
Sbjct: 73  SDRELVLARRQIGMIFQHFNLLSSRTVFENVALPLELESESKAKIQEKITALLDLVGLSE 132

Query: 538 AVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREA 597
                A  S LS GQK+R  IA  LA  P VLL DE  + LD  T   + + + EI R  
Sbjct: 133 K--RDAYPSNLSGGQKQRVAIARALASDPKVLLCDEATSALDPATTQSILKLLKEINRTL 190

Query: 598 GITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
           GIT ++ITH  EVVK +  D+V  +  G ++
Sbjct: 191 GITILLITHEMEVVKQI-CDQVAVIDQGRLV 220


>pir||D70020 ABC transporter (ATP-binding protein) homolog yusC - Bacillus
           subtilis >gi|2635771|emb|CAB15264.1| (Z99120) similar to
           ABC transporter (ATP-binding protein) [Bacillus
           subtilis]
           Length = 341
           
 Score = 83.5 bits (203), Expect = 7e-15
 Identities = 65/216 (30%), Positives = 102/216 (47%), Gaps = 32/216 (14%)

Query: 419 IQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEE 478
           +QD+ K +  +H  +    ++N++ +I  GE+  ++G SGAGK++L+RL+ G  K     
Sbjct: 4   LQDVSKVYKSKHGDVN--AVQNVSLSIKKGEIFGIIGYSGAGKSSLIRLLNGLEK----- 56

Query: 479 KYRPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEHVY----RKIRD------------ 522
              PTSG +EV       V   G  +       I +H      R +RD            
Sbjct: 57  ---PTSGTVEVAGTKINEVNGRGLRKARHEISMIFQHFNLLWSRTVRDNIMFPLEIAGVK 113

Query: 523 ----LNAAVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHL 578
               +  A E++   GL      ++  S+LS GQK+R  IA  LA  P VLL DE  + L
Sbjct: 114 KSERIKRANELIKLVGLEGKE--KSYPSQLSGGQKQRVGIARALANNPKVLLCDEATSAL 171

Query: 579 DTLTAMRVARKVSEIVREAGITAVIITHRPEVVKAL 614
           D  T   +   +S+I    G+T V+ITH   V++ +
Sbjct: 172 DPQTTDSILDLLSDINERLGLTIVLITHEMHVIRKI 207


>pir||T22813 hypothetical protein F57A10.3 - Caenorhabditis elegans
           >gi|3877814|emb|CAB09418.1| (Z96048) predicted using
           Genefinder~contains similarity to Pfam domain: PF00005
           (ABC transporter), Score=243.0, E-value=1.4e-69, N=1;
           PF00664 (ABC transporter transmembrane region.),
           Score=152.1, E-value=3.1e-42, N=1~cDNA EST EMBL:M75760
           comes from thi>
           Length = 733
           
 Score = 83.5 bits (203), Expect = 7e-15
 Identities = 69/226 (30%), Positives = 113/226 (49%), Gaps = 37/226 (16%)

Query: 425 AFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTS 484
           AFG   R    P+  N++F +  G++ AVVG+SG+GK+T+  L+L          Y PTS
Sbjct: 488 AFGYADR---DPLFHNISFDVPAGKITAVVGSSGSGKSTIASLLL--------RLYDPTS 536

Query: 485 GKIEV---------PKNAKVSVLIPGEIEPEFGSETILEHV-YRKIRDLNAA-VEVLNRA 533
           G+I V         P   +  +   G+ EP   S TI E++ Y  +   N    E+++ A
Sbjct: 537 GRILVDGTDLKDIDPSYWRRHIGTVGQ-EPVLFSTTIKENIIYGSLEPENVTDAEIVSAA 595

Query: 534 GLSDAVLYRAKF------------SELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTL 581
             S+A  + ++F            S LS GQK+R  IA  L  +PN+L++DE  + LD  
Sbjct: 596 DQSNADEFISRFPIKYDTKVGEHGSTLSGGQKQRIAIARALVNKPNILIMDEATSALDAS 655

Query: 582 TAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTV 627
           +   V   +++++  +  T +II HR   +K    D+++ V  G+V
Sbjct: 656 SEYLVRIALNKLLANSKQTVMIIAHRLSTIK--HADQIVVVDRGSV 699


>gb|AAA02976.1| (L06062) multi drug resistance P-glycoprotein [Leishmania donovani]
           Length = 518
           
 Score = 83.5 bits (203), Expect = 7e-15
 Identities = 68/243 (27%), Positives = 119/243 (47%), Gaps = 35/243 (14%)

Query: 398 VFKNVTKVFESELDIKGLPQE-IQDLLKAFGVRHRVIQRP---VLRNLNFTINPGEVVAV 453
           +FK + +V   ++D  G+P    +  ++   VR     RP   + R+LN TI  G+ VA 
Sbjct: 17  IFKAIDRVPPVDIDAGGVPVTGFKQSIEFRNVRFSYPTRPDMILFRDLNLTIKCGQKVAF 76

Query: 454 VGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKI--------EVPKNAKVSVLIPGEIEP 505
            G+SG GK++++ LI        +  Y P  G +        E+  +   + +     EP
Sbjct: 77  SGSSGCGKSSMIGLI--------QRFYDPVGGAVLCDGVDMRELCLHDWRNQIGIVSQEP 128

Query: 506 EFGSETILEHVYRKIRDLNAA----VEVLNRAGLSDAVL---------YRAKFSELSTGQ 552
              + T++E+V  ++   NA     +E   +A + D ++           A  S+LS GQ
Sbjct: 129 NLFAGTMMENV--RVGKPNATEEEVIEACRQANVHDTIMSLPDQYNTPVGAVGSQLSGGQ 186

Query: 553 KERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVK 612
           K+R  IA  L +RP VLL+DE  + LD  + M V R + ++++  G+T ++I HR   ++
Sbjct: 187 KQRIAIARALVKRPPVLLLDEATSALDRKSEMEVQRSLDQLMQRGGMTVIVIAHRLATIR 246

Query: 613 ALD 615
            +D
Sbjct: 247 NVD 249


>gb|AAC31907.1| (AF075709) ABC transporter ATP-binding subunit [Pseudomonas putida]
           Length = 270
           
 Score = 83.1 bits (202), Expect = 9e-15
 Identities = 67/226 (29%), Positives = 107/226 (46%), Gaps = 31/226 (13%)

Query: 412 IKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGA 471
           ++G+P     L K FG      QR VLR ++  I  G+ VA+VG SG GK+TLLRL+ G 
Sbjct: 12  LRGIPLASNGLRKTFG------QREVLRGIDLHIPAGQFVAIVGRSGCGKSTLLRLLAGL 65

Query: 472 IKGYWEEKYRPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEHVYRKIRD--------- 522
            +        PT+G++     A  + L     E     +      ++K+ D         
Sbjct: 66  DQ--------PTAGELL----AGAAPLAEAREETRLMFQDARLLPWKKVIDNVGLGLKGD 113

Query: 523 -LNAAVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTL 581
               A++ L   GL+D        + LS GQK+R  +A  L  +P +LL+DE    LD L
Sbjct: 114 WRQRALDALEAVGLADRA--NEWPAALSGGQKQRVALARALIHQPRLLLLDEPLGALDAL 171

Query: 582 TAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTV 627
           T + + + +  + R+ G T +++TH      A+  D+V+ +  G V
Sbjct: 172 TRIEMQQLIERLWRQHGFTVLLVTHDVNEAVAV-ADRVILIEDGEV 216


>gb|AAA02977.1| (L01572) P-glycoprotein [Leishmania donovani]
           Length = 1341
           
 Score = 83.1 bits (202), Expect = 9e-15
 Identities = 68/244 (27%), Positives = 119/244 (47%), Gaps = 37/244 (15%)

Query: 398 VFKNVTKVFESELDIKGLPQE-IQDLLKAFGVRHRVIQRP---VLRNLNFTINPGEVVAV 453
           +FK + +V   ++D  G+P    +  ++   VR     RP   + R+LN TI  G+ VA 
Sbjct: 426 IFKAIDRVPPVDIDAGGVPVTGFKQSIEFRNVRFSYPTRPDMILFRDLNLTIKCGQKVAF 485

Query: 454 VGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVP---------KNAKVSVLIPGEIE 504
            G+SG GK++++ LI        +  Y P  G +             + +  + I  + E
Sbjct: 486 SGSSGCGKSSMIGLI--------QRFYDPVGGAVLCDGVDLRELCLHDWRDQIGIVSQ-E 536

Query: 505 PEFGSETILEHVYRKIRDLNAA----VEVLNRAGLSDAVL---------YRAKFSELSTG 551
           P   + T++E+V  ++   NA     +E   +A + D ++           A  S+LS G
Sbjct: 537 PNLFAGTMMENV--RVGKPNATEEEVIEACRQANVHDTIMSLPDQYNTPVGAVGSQLSGG 594

Query: 552 QKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVV 611
           QK+R  IA  L +RP VLL+DE  + LD  + M V R + ++++  G+T ++I HR   +
Sbjct: 595 QKQRIAIARALVKRPPVLLLDEATSALDRKSEMEVQRSLDQLMQRGGMTVIVIAHRLATI 654

Query: 612 KALD 615
           + +D
Sbjct: 655 RNVD 658


>pir||G69192 ABC transporter (glutamine transport ATP-binding protein) -
           Methanobacterium thermoautotrophicum (strain Delta H)
           >gi|2621782|gb|AAB85201.1| (AE000849) ABC transporter
           (glutamine transport ATP-binding protein)
           [Methanobacterium thermoautotrophicum]
           Length = 220
           
 Score = 82.7 bits (201), Expect = 1e-14
 Identities = 67/210 (31%), Positives = 108/210 (50%), Gaps = 31/210 (14%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E++DL K+F       +   L  +N  ++ GE ++++G SG+GK+TLL +I GA+     
Sbjct: 5   EVRDLRKSFDSG----RIRALNGVNLEVDGGEFISIMGPSGSGKSTLLNMI-GALD---- 55

Query: 478 EKYRPTSGKI-----EVPKNAKVSVLIPGEIEPEF------GSETILEHV------YRKI 520
               P SG I     ++ +   +S L   EI   F       + T LE+V       +  
Sbjct: 56  ---VPDSGTICVAGRDLSRERDLSRLRAEEIGFVFQLHNLIPNLTALENVEIPMFAVKHE 112

Query: 521 RDLNAAVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDT 580
                A+E+L    L+D      K +ELS G+++R  IA  LA  P+++L DE    LD+
Sbjct: 113 NMEERAMELLEYVDLADKA--HRKPTELSGGERQRVAIARALANDPSIILADEPTGSLDS 170

Query: 581 LTAMRVARKVSEIVREAGITAVIITHRPEV 610
            T+ RV RK+ E+  + G+T V++TH P+V
Sbjct: 171 RTSQRVLRKLRELQEDEGVTLVVVTHEPDV 200


>emb|CAB01940.1| (Z79692) ExpD1 [Sinorhizobium meliloti]
           Length = 589
           
 Score = 82.3 bits (200), Expect = 1e-14
 Identities = 63/210 (30%), Positives = 105/210 (50%), Gaps = 35/210 (16%)

Query: 433 IQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKN 492
           I  P+++ +NF+++PGEV+ +VG S AGK+TL RL++G +K        PT+G + +  N
Sbjct: 363 IDVPIIKGINFSLSPGEVLGIVGPSAAGKSTLARLLVGILK--------PTAGGVFLDGN 414

Query: 493 ----------AKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLNRAGLSDA--VL 540
                      +++  +P  +    G  TI E++ R     +   +VL  A L+D   ++
Sbjct: 415 NVYLWERSSFGQIAGYLPQSVSLLEG--TIRENIARMAE--SDPYKVLEAARLADVHDMI 470

Query: 541 YRAKFS----------ELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKV 590
            R               LS GQ++R  +A  L  RP +L++DE  A+LD L    + R +
Sbjct: 471 GRLPLGYDTPVGDGHLTLSGGQRQRIAVARCLYGRPRLLVLDEPNANLDALGERALIRAI 530

Query: 591 SEIVREAGITAVIITHRPEVVKALDPDKVL 620
            E  R  G   ++I HRP +++  D   VL
Sbjct: 531 DE-ARSDGAIVILIAHRPAIMQVADKLLVL 559


>pir||G72255 ABC transporter, ATP-binding protein - Thermotoga maritima  (strain
           MSB8) >gi|4981982|gb|AAD36488.1|AE001794_4 (AE001794)
           ABC transporter, ATP-binding protein [Thermotoga
           maritima]
           Length = 245
           
 Score = 82.3 bits (200), Expect = 1e-14
 Identities = 60/222 (27%), Positives = 112/222 (50%), Gaps = 23/222 (10%)

Query: 421 DLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKY 480
           ++L+   V + V  + +L+ +N       V +++G +GAGK+TL  LI+G       E Y
Sbjct: 2   NVLELIDVWYEVEGKAILKGINARFEKQRVYSILGTNGAGKSTLAYLIMGL------EGY 55

Query: 481 RPTSGKI----------EVPKNAKVSVLIPGEIEPEFGSETILEHVY---RKIRDLNAAV 527
           RPT GKI           V + AK  + +  +    F    I +++    R+        
Sbjct: 56  RPTRGKILLDGEDITDLSVTERAKRGITLMWQEPARFTGIKIRDYLTLGGRRKVSKEELE 115

Query: 528 EVLNRAGLSDAVLYRAKFSE-LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRV 586
            VL   GL+ A+       E LS G+++R ++AS+L  +P   ++DE  + +D ++   +
Sbjct: 116 RVLELVGLNPALYLERNVDEKLSGGERKRVELASILLMKPRYTILDEPDSGIDIMSLEMI 175

Query: 587 ARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
            + +SE+V  AG + +++THR E+  AL+ D    + +G+++
Sbjct: 176 EKVLSELV-SAGGSVILVTHREEI--ALESDYAFLICHGSIL 214


>pir||A71243 probable maltose/maltodextrin transport ATP-binding protein -
           Pyrococcus horikoshii >gi|3256589|dbj|BAA29272.1|
           (AP000001) 362aa long hypothetical maltose/maltodextrin
           transport ATP-binding protein [Pyrococcus horikoshii]
           Length = 362
           
 Score = 82.3 bits (200), Expect = 1e-14
 Identities = 67/226 (29%), Positives = 113/226 (49%), Gaps = 32/226 (14%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           ++++++K FG          L N+N  I  GE +A++G SG+GK+TLL  I G       
Sbjct: 5   KLENIVKKFG------NFTALNNINLKIKDGEFMALLGPSGSGKSTLLYTIAGI------ 52

Query: 478 EKYRPTSGKIEVPKNAKVSVLIPGE--IEPEFGSETILEH--VYRKI-----------RD 522
             Y+PTSGKI   +   V+ L P +  +   F +  +  H  VY+ I            +
Sbjct: 53  --YKPTSGKIYFDEK-DVTELPPKDRNVGLVFQNWALYPHMTVYKNIAFPLELRKAPREE 109

Query: 523 LNAAVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLT 582
           ++  V  + +    D +L R  + +LS GQ++R  IA  L + P VLL+DE  ++LD L 
Sbjct: 110 IDKKVREVAKMLHIDKLLNRYPW-QLSGGQQQRVAIARALVKEPEVLLLDEPLSNLDALL 168

Query: 583 AMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
            + V  ++  + +E GIT V +TH      A+  D++  +  G ++
Sbjct: 169 RLEVRAELKRLQKELGITTVYVTHDQAEALAM-ADRIAVIREGEIL 213


>dbj|BAB04005.1| (AP001508) ABC transporter (ATP-binding protein) [Bacillus
           halodurans]
           Length = 259
           
 Score = 82.3 bits (200), Expect = 1e-14
 Identities = 71/229 (31%), Positives = 111/229 (48%), Gaps = 31/229 (13%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E+QDL K +G ++ + +   L+ +NF I PGE + ++G SG+GKTTLL  I   IK    
Sbjct: 9   EVQDLQKNYGKKNNLTK--ALKGVNFDILPGEFLGIMGPSGSGKTTLLNCIATIIK---- 62

Query: 478 EKYRPTSGKIEVP-KN---------AKVSVLIPGEIEPEF-------GSETILEHV-YRK 519
               PTSG++ +  KN         AK      G +  +F       G E IL  +    
Sbjct: 63  ----PTSGRVLLHGKNISAFDSKDLAKYRGSRIGYLFQDFELLDNLTGQENILLPLAIHG 118

Query: 520 IRDLNAAVEVLNRAGLSDAVLYRAKF-SELSTGQKERAKIASLLAERPNVLLIDEFAAHL 578
           +    A V++   A + D      KF S++S GQK+R   A  L   P+++L DE    L
Sbjct: 119 VDFTKARVKLDELASILDIADILHKFPSQMSGGQKQRVAAARCLISDPDIVLADEPTGAL 178

Query: 579 DTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTV 627
           DT +A  +  K+  I R +G T ++++H P         ++LF+  G +
Sbjct: 179 DTRSARTLMTKLESINRSSGRTILMVSHDPNAASFC--SRILFIQDGVI 225


>dbj|BAA77876.1| (D83536) ATP-binding protein ABC. [Escherichia coli]
           Length = 343
           
 Score = 81.9 bits (199), Expect = 2e-14
 Identities = 69/232 (29%), Positives = 107/232 (45%), Gaps = 35/232 (15%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           ++ ++ K F    R IQ   L N++  +  G++  V+GASGAGK+TL+R +         
Sbjct: 3   KLSNITKVFHQGTRTIQ--ALNNVSLHVPAGQIYGVIGASGAGKSTLIRCV--------N 52

Query: 478 EKYRPTSGKIEVPKNAKVSVLIPGEIEPE-------------FGSETILEHVYRKIRDLN 524
              RPT G + V    +++ L   E+                  S T+  +V  ++   N
Sbjct: 53  LLERPTEGSVLVD-GQELTTLSESELTKARRQIGMIFQHFNLLSSRTVFGNVALRLELDN 111

Query: 525 A--------AVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAA 576
                      E+L+  GL D   + +  S LS GQK+R  IA  LA  P VLL DE  +
Sbjct: 112 TPKDEVKRRVTELLSLVGLGDK--HDSYPSNLSGGQKQRVAIARALASNPKVLLCDEATS 169

Query: 577 HLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
            LD  T   +   + +I R  G+T ++ITH  +VVK +  D V  +  G +I
Sbjct: 170 ALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRI-CDCVAVISNGELI 220


>sp|P54537|YQIZ_BACSU PROBABLE AMINO-ACID ABC TRANSPORTER ATP-BINDING PROTEIN IN
           BMRU-ANSR INTERGENIC REGION >gi|7442518|pir||H69962
           ABC-type transport protein yqiZ - Bacillus subtilis
           >gi|1303951|dbj|BAA12606.1| (D84432) YqiZ [Bacillus
           subtilis] >gi|2634830|emb|CAB14327.1| (Z99116) similar
           to amino acid ABC transporter (ATP-binding protein)
           [Bacillus subtilis]
           Length = 240
           
 Score = 81.9 bits (199), Expect = 2e-14
 Identities = 71/228 (31%), Positives = 116/228 (50%), Gaps = 32/228 (14%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLIL-------G 470
           +++ L K+FG      +  VL+N++ TI  GEVVAV+G SG+GK+T LR +        G
Sbjct: 3   KVEKLSKSFG------KHEVLKNISTTIAEGEVVAVIGPSGSGKSTFLRCLNLLEKPNGG 56

Query: 471 AIKGYWEEKYRPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEHVY---------RKIR 521
            I     E  +P +  ++V +N    + +  +    F  +T+LE++           K  
Sbjct: 57  TITIKDTEITKPKTNTLKVREN----IGMVFQHFHLFPHKTVLENIMYAPVNVKKESKQA 112

Query: 522 DLNAAVEVLNRAGLSDAVLYRAKF-SELSTGQKERAKIASLLAERPNVLLIDEFAAHLDT 580
               A ++L + GL +    R  + + LS GQK+R  IA  LA  P+++L DE  + LD 
Sbjct: 113 AQEKAEDLLRKVGLFEK---RNDYPNRLSGGQKQRVAIARALAMNPDIMLFDEPTSALDP 169

Query: 581 LTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
                V + + E+V E G+T VI+TH     K +  D+VLF+  G ++
Sbjct: 170 EMVKEVLQVMKELV-ETGMTMVIVTHEMGFAKEV-ADRVLFMDQGMIV 215


>pir||G81955 ABC-transport system ATP-binding protein NMA0393 [imported] -
           Neisseria meningitidis (group A strain Z2491)
           >gi|7379146|emb|CAB83694.1| (AL162753) ABC-transport
           system ATP-binding protein [Neisseria meningitidis
           Z2491]
           Length = 312
           
 Score = 81.5 bits (198), Expect = 3e-14
 Identities = 62/205 (30%), Positives = 101/205 (49%), Gaps = 27/205 (13%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E+  L K FG       + V  ++  T+  G+++AV+G SG GK+TLL +I G +     
Sbjct: 3   ELNGLCKRFG------GKTVADDICLTVGRGKILAVLGRSGCGKSTLLNMIAGIV----- 51

Query: 478 EKYRPTSGKIEV---------PKNAKVSVLIPG-EIEPEFGSETILEHVYRKIRDLNAAV 527
              RP  G+I +         P+  ++S++     + P   +        +  +   A  
Sbjct: 52  ---RPDGGEIWLNGENITRMPPEKRRISLMFQDYALFPHMSALENAAFGLKMQKMPKAEA 108

Query: 528 EVLNRAGLSDAVL---YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAM 584
           E L  A L++  L      K  +LS G+K+R  +A  L  RP++LL+DE  + LDT    
Sbjct: 109 ESLAMAALAEVGLENEAHRKPEKLSGGEKQRLALARALVVRPSLLLLDESFSSLDTHLRD 168

Query: 585 RVARKVSEIVREAGITAVIITHRPE 609
           R+ R  +E +R+ GI AV++TH PE
Sbjct: 169 RLRRMTAERIRKGGIPAVLVTHSPE 193


>pir||E72757 probable phosphate transport ATP-binding protein pstB APE0050 -
           Aeropyrum pernix (strain K1) >gi|5103438|dbj|BAA78959.1|
           (AP000058) 253aa long hypothetical phosphate transport
           ATP-binding protein pstB [Aeropyrum pernix]
           Length = 253
           
 Score = 81.1 bits (197), Expect = 3e-14
 Identities = 63/224 (28%), Positives = 112/224 (49%), Gaps = 19/224 (8%)

Query: 423 LKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLI------LGAIKGYW 476
           ++  G+   +  + +L+ ++F   PG V A++G SG+GK+TL+R+I      +   +   
Sbjct: 6   VRVSGLNVWITDKHILKGISFKAQPGTVTAIMGPSGSGKSTLIRVINRLIDLIPGARVEG 65

Query: 477 EEKYRPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEHVY---------RKIRDLNAAV 527
           E      +   E P N +    +  +    F   TI E+V          +  ++L+  V
Sbjct: 66  EVWINNMNVMKEDPYNIRRYTGMVFQEPNPFPHMTIYENVAIGPKLHGLAKNKKELDEIV 125

Query: 528 E-VLNRAGLSDAVLYRAKF--SELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAM 584
           E  L  A L D V  R      +LS GQ++R  +A  LA +P VLL+DE  A++D ++ +
Sbjct: 126 EWALKMAHLWDEVKDRLSDYPHQLSGGQRQRLSLARALALKPRVLLLDEPTANIDPVSTV 185

Query: 585 RVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
           ++ + + E  +E   T +I+TH P+    +  D++LF+  G VI
Sbjct: 186 KIEQSIVEYAKEEMATVIIVTHTPQQAARIS-DQILFLYEGRVI 228


>pir||G81012 spermidine/putrescine ABC transporter, ATP-binding protein NMB2042
           [imported] - Neisseria meningitidis (group B strain
           MD58) >gi|7227304|gb|AAF42363.1| (AE002554)
           spermidine/putrescine ABC transporter, ATP-binding
           protein [Neisseria meningitidis MC58]
           Length = 312
           
 Score = 81.1 bits (197), Expect = 3e-14
 Identities = 62/205 (30%), Positives = 99/205 (48%), Gaps = 27/205 (13%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E+  L K FG       + V  N+  T+  G+++AV+G SG GK+TLL +I G +     
Sbjct: 3   ELNGLCKRFG------NKTVADNICLTVGRGKILAVLGRSGCGKSTLLNIIAGIV----- 51

Query: 478 EKYRPTSGKIEV---------PKNAKVSVLIPG-EIEPEFGSETILEHVYRKIRDLNAAV 527
              RP  G+I +         P+  ++S++     + P   +        +  +   A  
Sbjct: 52  ---RPDGGEIWLNGENITRMPPEKRRISLMFQDYALFPHMSALENAAFGLKMQKMPKAEA 108

Query: 528 EVLNRAGLSDAVL---YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAM 584
           E L  A L++  L      K  +LS G+K+R  +A  L  RP++LL+DE  + LDT    
Sbjct: 109 ERLAMAALAEVGLENEAHRKPEKLSGGEKQRLALARALVVRPSLLLLDESFSSLDTHLRG 168

Query: 585 RVARKVSEIVREAGITAVIITHRPE 609
            + R  +E +R  GI AV++TH PE
Sbjct: 169 TLRRMTAERIRNGGIPAVLVTHSPE 193


>dbj|BAB07610.1| (AP001520) ABC transporter (ATP-binding protein) [Bacillus
           halodurans]
           Length = 577
           
 Score = 81.1 bits (197), Expect = 3e-14
 Identities = 74/241 (30%), Positives = 117/241 (47%), Gaps = 34/241 (14%)

Query: 399 FKNVTKVFESELDIKGLPQ----EIQDLLKAFGVRHRVI-QRPVLRNLNFTINPGEVVAV 453
           FK  T++ ++E DI+  P      IQ  ++  GVR        VL+N++ TI  GE VA 
Sbjct: 304 FKRYTEILDTEPDIEDAPGAKEWNIQGNIQYEGVRFGYDGMEDVLKNIDLTIRAGETVAF 363

Query: 454 VGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVP----KNAKVSVLIP--GEIEPE- 506
           VG SGAGKTTL  L+           Y    G+I V     +  K+  L    G ++ + 
Sbjct: 364 VGPSGAGKTTLCSLL--------PRFYEVKDGRIVVDGLDIREMKLESLRNQIGIVQQDV 415

Query: 507 -FGSETILEHV-YRKIRDLNAAV-EVLNRAGLSDAVLYRAKFSE---------LSTGQKE 554
              S T+ E++ Y  ++  +  + E   +A L D +L +    E         LS GQK+
Sbjct: 416 FLFSGTVKENIAYGNLQATDEEIMEAARKAKLDDFILSQPDGLETVIGERGVKLSGGQKQ 475

Query: 555 RAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKAL 614
           R  IA +  + P +L++DE  + LDT T + + + +SE+ +  G T ++I HR   +K  
Sbjct: 476 RLSIARMFLKNPPILILDEATSALDTETELAIQQSLSELSK--GRTTLVIAHRLATIKNA 533

Query: 615 D 615
           D
Sbjct: 534 D 534


>pir||T32865 hypothetical protein ZK484.2 - Caenorhabditis elegans
           >gi|2746911|gb|AAB95060.1| (AF040659) similar to the
           ATP-binding transport protein family [Caenorhabditis
           elegans]
           Length = 811
           
 Score = 80.4 bits (195), Expect = 6e-14
 Identities = 62/213 (29%), Positives = 102/213 (47%), Gaps = 34/213 (15%)

Query: 436 PVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVP----- 490
           P++ +L FT+ PGEVVA+VG SG GK++ + ++        E  Y PTSG++ +      
Sbjct: 534 PIMEDLTFTVEPGEVVALVGPSGGGKSSCIAML--------EHFYEPTSGEVLIDGVPVR 585

Query: 491 ----KNAKVSVLIPGEIEPEFGSETILEH------------VYRKIRDLNAAVEVLNRAG 534
               K     V + G+ EP   + ++ E+            V    +  NA   ++N   
Sbjct: 586 EYDHKFLHTKVALVGQ-EPVLYARSVTENIGYGLDKYDDDMVQNSAKLANAHTFIMNDTT 644

Query: 535 LSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIV 594
                    K S++S GQK+R  IA  L  +P VLL+DE  + LD  +   V   +S+ +
Sbjct: 645 DGYNTNVGEKGSQMSGGQKQRIAIARALVRQPVVLLLDEATSALDAESEHTVQEAISKNL 704

Query: 595 REAGITAVIITHRPEVVKALDPDKVLFVGYGTV 627
           +  G T ++I HR   V+  + DK++ +  G V
Sbjct: 705 K--GKTVILIAHRLSTVE--NADKIVVINKGKV 733


>emb|CAB41455.1| (Y08703) ABC transporter [Sinorhizobium meliloti]
           Length = 589
           
 Score = 80.4 bits (195), Expect = 6e-14
 Identities = 62/207 (29%), Positives = 103/207 (48%), Gaps = 35/207 (16%)

Query: 436 PVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKN--- 492
           P+++ +NF+++PGEV+ +VG S AGK+TL RL+ G +K        PT+G + +  N   
Sbjct: 366 PIIKGINFSLSPGEVLGIVGPSAAGKSTLARLLTGILK--------PTAGGVFLDGNNVY 417

Query: 493 -------AKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLNRAGLSDA--VLYRA 543
                   +V+  +P  +    G  TI E++ R     +   +VL  A L+D   ++ R 
Sbjct: 418 LWERSSFGQVAGYLPQSVSLLEG--TIRENIARMAE--SDPYKVLEAARLADVHDMIGRL 473

Query: 544 KFS----------ELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEI 593
                         LS GQ++R  +A  L  RP +L++DE  A+LD +    + R + E 
Sbjct: 474 PLGYDTPVGDGHLTLSGGQRQRIALARCLYGRPRLLVLDEPNANLDAIGERALIRAIEE- 532

Query: 594 VREAGITAVIITHRPEVVKALDPDKVL 620
            R  G   ++I HRP +++  D   VL
Sbjct: 533 ARRDGAIVILIAHRPAIMQVADKLLVL 559


>pir||H64716 ABC transporter, ATP-binding protein - Helicobacter pylori  (strain
           26695) >gi|2314761|gb|AAD08616.1| (AE000655) ABC
           transporter, ATP-binding protein (abc) [Helicobacter
           pylori 26695]
           Length = 327
           
 Score = 80.4 bits (195), Expect = 6e-14
 Identities = 66/216 (30%), Positives = 109/216 (49%), Gaps = 31/216 (14%)

Query: 438 LRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEV-------- 489
           L+ +N  +  G+++ V+G SGAGK+TL+RLI            RP+SG++ V        
Sbjct: 19  LKGVNLELKKGDILGVIGYSGAGKSTLIRLI--------NCLERPSSGEVLVNGVNLLKL 70

Query: 490 -PKNAKVSVLIPGEIEPEFG---SETILEHV--------YRKIRDLNAAVEVLNRAGLSD 537
            PK  + +    G I   F    ++ + E+V        + K +  +   E+L   GL D
Sbjct: 71  KPKELQKARQKIGMIFQHFNLLSAKNVFENVAFALEIARWEKNKIKSRVHELLELVGLED 130

Query: 538 AVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREA 597
            + +  K  +LS GQK+R  IA  LA  P++LL DE  + LD+ T   +   +S I ++ 
Sbjct: 131 KMHFYPK--QLSGGQKQRVAIARSLANCPDLLLCDEATSALDSKTTHSILTLLSGIQKKL 188

Query: 598 GITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
            ++ V ITH  EVVK L  +++  +  G ++ R S+
Sbjct: 189 DLSIVFITHEIEVVKEL-CNQMCVISSGEIVERGSV 223


>pir||G83214 probable ATP-binding component of ABC transporter PA3442 [imported]
           - Pseudomonas aeruginosa (strain PAO1)
           >gi|9949583|gb|AAG06830.1|AE004765_3 (AE004765) probable
           ATP-binding component of ABC transporter [Pseudomonas
           aeruginosa]
           Length = 274
           
 Score = 80.4 bits (195), Expect = 6e-14
 Identities = 62/221 (28%), Positives = 114/221 (51%), Gaps = 23/221 (10%)

Query: 413 KGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAI 472
           +G+P  ++ + + FG      +R VL++++  +  G+ VA+VG SG GK+TLLRL+ G  
Sbjct: 17  RGIPLALRGVARRFG------EREVLKDIDLLVPAGQFVAIVGRSGCGKSTLLRLLAGLD 70

Query: 473 KGYWEEKYRPTSGKIEVPKNAKV----SVLIPGEIEPEFGSETILEHVYRKIR-DLNA-A 526
           +    E    ++   E  ++ ++    S L+P +         ++++V   +R D  A A
Sbjct: 71  QPSRGELLAGSAALAEAREDTRLMFQDSRLLPWK--------RVIDNVGLGLRGDWRAKA 122

Query: 527 VEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRV 586
           ++ L   GL++        + LS GQK+R  +A  L   P +LL+DE    LD LT + +
Sbjct: 123 LQALRAVGLAERA--NEWPAALSGGQKQRVALARALIHEPRLLLLDEPLGALDALTRIEM 180

Query: 587 ARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTV 627
            + +  + RE G T +++TH      A+  D+V+ +  G +
Sbjct: 181 QQLIEGLWREHGFTVLLVTHDVSEAVAV-ADRVILIEDGEI 220


>pir||F72510 probable multiple sugar-binding transport ATP-binding protein
           APE2060 - Aeropyrum pernix (strain K1)
           >gi|5105758|dbj|BAA81070.1| (AP000063) 388aa long
           hypothetical multiple sugar-binding transport
           ATP-binding protein [Aeropyrum pernix]
           Length = 388
           
 Score = 80.4 bits (195), Expect = 6e-14
 Identities = 58/204 (28%), Positives = 105/204 (51%), Gaps = 24/204 (11%)

Query: 438 LRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKI--------EV 489
           +R++N  I   E V+++G SG+GKTTLL LI G         Y+P+ G+I        ++
Sbjct: 16  VRDVNLYIEDKEFVSILGPSGSGKTTLLYLIAGI--------YKPSRGRIYFNDVDVTDL 67

Query: 490 PKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLNRAGLSDAVLYRAKF---- 545
           P N K ++ +  +    +   T+ E++   +R  N     +    LS A L   +     
Sbjct: 68  PPN-KRNIGLVFQNYALYPHMTVYENIAFPLRLRNFGEPAIKEKVLSVAKLLGIEGLLDR 126

Query: 546 --SELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVI 603
             ++LS GQ++R  +A  L + P VLL+DE  ++LD L  +++  ++ ++ +E GITA+ 
Sbjct: 127 YPAQLSGGQQQRVALARALVKEPEVLLLDEPLSNLDALLRIKIRSELKKLQKELGITAIY 186

Query: 604 ITHRPEVVKALDPDKVLFVGYGTV 627
           +TH      A+  D++  +  G +
Sbjct: 187 VTHDQSEALAM-ADRIAIIASGVI 209


>gi|10955699 ABC transporter [Yersinia pestis] >gi|7467316|pir||T14673 ABC
           transport protein - Yersinia pestis plasmid pMT1
           >gi|2996308|gb|AAC13188.1| (AF053947) ABC transporter
           [Yersinia pestis]
           Length = 212
           
 Score = 80.0 bits (194), Expect = 7e-14
 Identities = 60/199 (30%), Positives = 96/199 (48%), Gaps = 26/199 (13%)

Query: 421 DLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKY 480
           ++ ++FG+     +  +  NL   +  G+VV + G SG+GK+ +LR              
Sbjct: 22  EIAESFGLGLDEKEWTLYDNLELEVKQGDVVYITGQSGSGKSVVLR-------------- 67

Query: 481 RPTSGKIEVPKNAKVSVLIPGEIEP-EFGSET-ILEHVYRKIRDLNAAVEVLNRAGLSDA 538
                  E+ +  K   L    I+   F +E  +++ + +   D   A+ +L+ AGL+DA
Sbjct: 68  -------ELQRQMKDEGLSVASIDDFTFNNEVNVIDQLGKTTSD---ALGLLSMAGLNDA 117

Query: 539 VLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAG 598
            L+  K SE+S GQK R KIA L+     V   DEF A LD +TA  VA  +    R+ G
Sbjct: 118 YLFVRKPSEMSDGQKYRLKIAKLIESGAKVWAADEFGAVLDRVTAQVVASNLQRAARKVG 177

Query: 599 ITAVIITHRPEVVKALDPD 617
            T ++ T   ++  AL PD
Sbjct: 178 ATVMVATTHEDLKNALRPD 196


>gi|10955870 putative ABC transporter [Yersinia pestis] >gi|7467450|pir||T14941
           probable ABC transporter - Yersinia pestis plasmid pMT1
           >gi|3883026|gb|AAC82686.1| (AF074611) putative ABC
           transporter [Yersinia pestis]
           >gi|5834712|emb|CAB55209.1| (AL117211) putative ABC
           transporter ATP-binding protein [Yersinia pestis]
           Length = 232
           
 Score = 80.0 bits (194), Expect = 7e-14
 Identities = 60/199 (30%), Positives = 96/199 (48%), Gaps = 26/199 (13%)

Query: 421 DLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKY 480
           ++ ++FG+     +  +  NL   +  G+VV + G SG+GK+ +LR              
Sbjct: 42  EIAESFGLGLDEKEWTLYDNLELEVKQGDVVYITGQSGSGKSVVLR-------------- 87

Query: 481 RPTSGKIEVPKNAKVSVLIPGEIEP-EFGSET-ILEHVYRKIRDLNAAVEVLNRAGLSDA 538
                  E+ +  K   L    I+   F +E  +++ + +   D   A+ +L+ AGL+DA
Sbjct: 88  -------ELQRQMKDEGLSVASIDDFTFNNEVNVIDQLGKTTSD---ALGLLSMAGLNDA 137

Query: 539 VLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAG 598
            L+  K SE+S GQK R KIA L+     V   DEF A LD +TA  VA  +    R+ G
Sbjct: 138 YLFVRKPSEMSDGQKYRLKIAKLIESGAKVWAADEFGAVLDRVTAQVVASNLQRAARKVG 197

Query: 599 ITAVIITHRPEVVKALDPD 617
            T ++ T   ++  AL PD
Sbjct: 198 ATVMVATTHEDLKNALRPD 216


>gb|AAB69130.1| (U63320) P-glycoprotein [Leishmania tropica]
           Length = 1341
           
 Score = 80.0 bits (194), Expect = 7e-14
 Identities = 66/244 (27%), Positives = 117/244 (47%), Gaps = 37/244 (15%)

Query: 398 VFKNVTKVFESELDIKGLPQE-IQDLLKAFGVRHRVIQRP---VLRNLNFTINPGEVVAV 453
           +FK + +V   ++D  G+P    +  ++   VR     RP   + R+LN  I  G+ VA 
Sbjct: 426 IFKAIDRVPPVDIDADGVPVTGFKQSIEFRNVRFSYPTRPDMILFRDLNLKIKCGQKVAF 485

Query: 454 VGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVP---------KNAKVSVLIPGEIE 504
            G+SG GK++++ LI        +  Y P  G +             + +  + I  + E
Sbjct: 486 SGSSGCGKSSMIGLI--------QRFYDPAGGAVLCDGVDMRELCLHDWRDQIGIVSQ-E 536

Query: 505 PEFGSETILEHVYRKIRDLNAA----VEVLNRAGLSDAVL---------YRAKFSELSTG 551
           P   + T++E+V  ++   NA     +E   +A + D ++           A  S+LS G
Sbjct: 537 PILFAGTMMENV--RVGKPNATEEEVIEACRQANVHDTIMSLPDQYNTPVGAVGSQLSGG 594

Query: 552 QKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVV 611
           QK+R  IA  L +RP +LL+DE  + LD  + M V R + +++   G+T ++I HR   +
Sbjct: 595 QKQRIAIARALVKRPPILLLDEATSALDRKSEMEVQRSLDQLMERGGVTVIVIAHRLATI 654

Query: 612 KALD 615
           + +D
Sbjct: 655 RNVD 658


>gi|11498288 glutamine ABC transporter, ATP-binding protein (glnQ)
           [Archaeoglobus fulgidus] >gi|7442524|pir||H69334
           glutamine transport protein glnQ - Archaeoglobus
           fulgidus >gi|2649950|gb|AAB90561.1| (AE001058) glutamine
           ABC transporter, ATP-binding protein (glnQ)
           [Archaeoglobus fulgidus]
           Length = 242
           
 Score = 80.0 bits (194), Expect = 7e-14
 Identities = 68/231 (29%), Positives = 109/231 (46%), Gaps = 38/231 (16%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           EI DL K FG      +  VL+ +   +  GEVV ++G SG+GK+TLLR I         
Sbjct: 5   EIIDLHKRFG------ELEVLKGVTMKVEKGEVVVIIGPSGSGKSTLLRCI--------N 50

Query: 478 EKYRPTSGKIEVP----KNAKVSV-LIPGEIEPEFGSETILEHVYR---------KIRDL 523
               PTSGKI +      N+K+ +  +   I   F    +  H+           KI+ +
Sbjct: 51  RLEEPTSGKILLDGVDITNSKIDINKVRQRIGIVFQQFNLFPHLTALQNVTLAPIKIKKM 110

Query: 524 N------AAVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAH 577
           +        + +L + GL D   Y    ++LS GQ++R  IA  LA  P V+L DE  + 
Sbjct: 111 SKREAEELGMRLLEKVGLEDKADYYP--AQLSGGQQQRVAIARALAMNPEVMLFDEVTSA 168

Query: 578 LDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
           LD      V   + ++ R+ G+T V++TH     + +  D+V+F+  G ++
Sbjct: 169 LDPELVKEVLDVMKQLARD-GMTMVVVTHEMGFAREVG-DRVIFMDGGVIV 217


>gi|9955963 ATP-binding cassette, sub-family B, member 6 [Homo sapiens]
           >gi|8452823|gb|AAF75107.1|AF076775_1 (AF076775) MT-ABC
           transporter [Homo sapiens] >gi|8547018|dbj|BAA96733.1|
           (AB039371) mitochondrial ABC transporter 3 [Homo
           sapiens] >gi|9187501|emb|CAB95766.2| (AJ289233) ABC
           transporter umat [Homo sapiens]
           Length = 842
           
 Score = 80.0 bits (194), Expect = 7e-14
 Identities = 60/216 (27%), Positives = 110/216 (50%), Gaps = 33/216 (15%)

Query: 435 RPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAK 494
           R  L++++FT+ PG+ +A+VG SGAGK+T+LRL+           Y  +SG I +     
Sbjct: 603 RETLQDVSFTVMPGQTLALVGPSGAGKSTILRLLF--------RFYDISSGCIRI-DGQD 653

Query: 495 VSVLIPGEIEPEFG---------SETILEHV-YRKIRDLNAAVE-VLNRAGLSDAVL--- 540
           +S +    +    G         ++TI +++ Y ++   N  VE     AG+ DA++   
Sbjct: 654 ISQVTQASLRSHIGVVPQDTVLFNDTIADNIRYGRVTAGNDEVEAAAQAAGIHDAIMAFP 713

Query: 541 --YRAKFSE----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIV 594
             YR +  E    LS G+K+R  IA  + + P ++L+DE  + LDT     +   ++++ 
Sbjct: 714 EGYRTQVGERGLKLSGGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAKVC 773

Query: 595 REAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVR 630
             A  T +++ HR   V  ++ D++L +  G ++ R
Sbjct: 774 --ANRTTIVVAHRLSTV--VNADQILVIKDGCIVER 805


>gb|AAC28653.1| (AF070598) ABC transporter [Homo sapiens]
           Length = 511
           
 Score = 80.0 bits (194), Expect = 7e-14
 Identities = 60/216 (27%), Positives = 110/216 (50%), Gaps = 33/216 (15%)

Query: 435 RPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAK 494
           R  L++++FT+ PG+ +A+VG SGAGK+T+LRL+           Y  +SG I +     
Sbjct: 272 RETLQDVSFTVMPGQTLALVGPSGAGKSTILRLLF--------RFYDISSGCIRI-DGQD 322

Query: 495 VSVLIPGEIEPEFG---------SETILEHV-YRKIRDLNAAVE-VLNRAGLSDAVL--- 540
           +S +    +    G         ++TI +++ Y ++   N  VE     AG+ DA++   
Sbjct: 323 ISQVTQASLRSHIGVVPQDTVLFNDTIADNIRYGRVTAGNDEVEAAAQAAGIHDAIMAFP 382

Query: 541 --YRAKFSE----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIV 594
             YR +  E    LS G+K+R  IA  + + P ++L+DE  + LDT     +   ++++ 
Sbjct: 383 EGYRTQVGERGLKLSGGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAKVC 442

Query: 595 REAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVR 630
             A  T +++ HR   V  ++ D++L +  G ++ R
Sbjct: 443 --ANRTTIVVAHRLSTV--VNADQILVIKDGCIVER 474


>gb|AAG33617.1|AF308472_1 (AF308472) ATP-binding cassette half-transporter [Homo sapiens]
           Length = 896
           
 Score = 80.0 bits (194), Expect = 7e-14
 Identities = 60/216 (27%), Positives = 110/216 (50%), Gaps = 33/216 (15%)

Query: 435 RPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAK 494
           R  L++++FT+ PG+ +A+VG SGAGK+T+LRL+           Y  +SG I +     
Sbjct: 657 RETLQDVSFTVMPGQTLALVGPSGAGKSTILRLLF--------RFYDISSGCIRI-DGQD 707

Query: 495 VSVLIPGEIEPEFG---------SETILEHV-YRKIRDLNAAVE-VLNRAGLSDAVL--- 540
           +S +    +    G         ++TI +++ Y ++   N  VE     AG+ DA++   
Sbjct: 708 ISQVTQASLRSHIGVVPQDTVLFNDTIADNIRYGRVTAGNDEVEAAAQAAGIHDAIMAFP 767

Query: 541 --YRAKFSE----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIV 594
             YR +  E    LS G+K+R  IA  + + P ++L+DE  + LDT     +   ++++ 
Sbjct: 768 EGYRTQVGERGLKLSGGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAKVC 827

Query: 595 REAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVR 630
             A  T +++ HR   V  ++ D++L +  G ++ R
Sbjct: 828 --ANRTTIVVAHRLSTV--VNADQILVIKDGCIVER 859


>gb|AAA88774.1| (U47048) MtfB [Escherichia coli]
           Length = 707
           
 Score = 79.6 bits (193), Expect = 1e-13
 Identities = 67/224 (29%), Positives = 106/224 (46%), Gaps = 35/224 (15%)

Query: 411 DIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILG 470
           D+  +  E QDL      R+     PV  NLN +I PGE VA+ GASG+GKTTL++++ G
Sbjct: 489 DMYPVALETQDL----SFRYDSQSAPVFSNLNISIKPGESVAITGASGSGKTTLMKVLCG 544

Query: 471 AIKGYWEEKYRPTSGKIEVP--------KNAKVSVLIPGEIEPEFGSETILEHVYRKIRD 522
            +         P SG++ +          N    ++     +    S +I E++     +
Sbjct: 545 LLV--------PESGRVMIDGTDIRSLGVNNYHKIISCVMQDDRLFSGSIRENICGFTEN 596

Query: 523 LNAA--VEVLNRAGLSDAVL-----YRAKFSE----LSTGQKERAKIASLLAERPNVLLI 571
           ++ A  VE    + + D ++     Y     E    LS GQK+R  IA  L  RP +L +
Sbjct: 597 IDEAWMVECARASFIHDVIIKMPMGYDTLIGELGEGLSGGQKQRIFIARALYRRPGILFM 656

Query: 572 DEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALD 615
           DE  + LDT +       V++ +++  IT +II HR   VK+ D
Sbjct: 657 DEATSALDTESEY----YVNQAIKQLNITRIIIAHRETTVKSAD 696


>pir||H72704 probable iron (III) dicitrate transport ATP-binding protein APE1055
           - Aeropyrum pernix (strain K1)
           >gi|5104725|dbj|BAA80040.1| (AP000060) 250aa long
           hypothetical iron (III) dicitrate transport ATP-binding
           protein [Aeropyrum pernix]
           Length = 250
           
 Score = 79.6 bits (193), Expect = 1e-13
 Identities = 62/201 (30%), Positives = 96/201 (46%), Gaps = 39/201 (19%)

Query: 436 PVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKV 495
           PVLR ++F+++PG +VA++G +G+GKTTLLRL+ G IK        P+ G++EV  +   
Sbjct: 21  PVLRGVSFSLDPGSLVALLGPNGSGKTTLLRLLAGIIK--------PSRGRVEVCGSP-- 70

Query: 496 SVLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLNRAGLSDAV---------------- 539
               PG +    G       V  +++ +  A  +L R G+S+ V                
Sbjct: 71  ----PGRVRRMLGYAPASPEVDPRLKAVEVA--LLYRYGVSEGVAWGRRDWEEVLAALGE 124

Query: 540 -----LYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIV 594
                L   ++ ELS+GQ+    +A +LA RP + L+DE  + LD     RV   +  + 
Sbjct: 125 MGVGELAWRRWGELSSGQRRLVILAGVLARRPGLALLDEPHSFLDVSNMRRVTLVLRSLR 184

Query: 595 REAGITAVIITHRPEVVKALD 615
             A  T V  TH P    A D
Sbjct: 185 GRA--TIVYTTHDPLAAMAAD 203


>pir||H70432 ABC transporter - Aquifex aeolicus >gi|2983897|gb|AAC07448.1|
           (AE000744) ABC transporter [Aquifex aeolicus]
           Length = 247
           
 Score = 79.2 bits (192), Expect = 1e-13
 Identities = 64/214 (29%), Positives = 104/214 (47%), Gaps = 34/214 (15%)

Query: 437 VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEV----PKN 492
           V + ++F +   ++VA+VG SGAGKTTLLRLILG +K        P  G++ +     KN
Sbjct: 17  VHKGISFKVESSQIVAIVGGSGAGKTTLLRLILGLLK--------PLKGEVRLFGKSIKN 68

Query: 493 AKVSVL--------IPGEIEPEFGSETILEHVY----------RKIRDLNAAVEVLNRAG 534
                L        +  +    FGS T+LE+V           R I ++NA  + L+  G
Sbjct: 69  LSEEELQKLRDRMGVVFQFSALFGSMTVLENVMYPVIKKRKLDRSIVEMNACFK-LSVCG 127

Query: 535 LSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIV 594
           L     Y+    ELS G K++  +A  L+  P +L++DE  + LD ++A      +  + 
Sbjct: 128 LKPEDFYKYP-QELSGGMKKKTALARALSLDPELLILDEPTSGLDPISAEEFDNLIKTVR 186

Query: 595 REAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
              G T +++TH    ++    DKVL +  G ++
Sbjct: 187 DTFGTTVIMVTHDLPSLRIC--DKVLALREGKIV 218


>pir||D75609 amino acid ABC transporter, ATP-binding protein - Deinococcus
           radiodurans (strain R1)
           >gi|6460517|gb|AAF12223.1|AE001862_49 (AE001862) amino
           acid ABC transporter, ATP-binding protein [Deinococcus
           radiodurans]
           Length = 309
           
 Score = 79.2 bits (192), Expect = 1e-13
 Identities = 73/231 (31%), Positives = 108/231 (46%), Gaps = 40/231 (17%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E Q+++K+FG         VL++++ T+  GE+V ++G SG GK+TLLRL+         
Sbjct: 3   EFQNVIKSFG------GPAVLQDISLTVPTGELVILIGPSGCGKSTLLRLV--------N 48

Query: 478 EKYRPTSGKIEVPKNAKVSVLIPGEIEPE------------FGSETILEHVY-------- 517
               PTSG I V     VSVL    +               F   T+ E+V         
Sbjct: 49  RLLEPTSGDIRV---GGVSVLEQDPVALRRRLGYVIQSVGLFPHLTVQENVELVPSISGV 105

Query: 518 -RKIRDLNAAVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAA 576
            R+ R    A+E+L+  GL           +LS GQ++R  IA  LA  P  LL+DE  +
Sbjct: 106 GRETRAAR-ALELLSLMGLEPGQYAGRYPRQLSGGQQQRVGIARALAADPEYLLMDEPFS 164

Query: 577 HLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTV 627
            LD +T  R+  +   + RE G T V +TH  +    L  D++  +G GTV
Sbjct: 165 ALDPITRARLQEQFLTLKREIGKTIVFVTHDVDEAVRLG-DRICVLGNGTV 214


>gb|AAF61810.1| (AF129811) unknown [Moraxella catarrhalis]
           Length = 690
           
 Score = 78.8 bits (191), Expect = 2e-13
 Identities = 61/197 (30%), Positives = 99/197 (49%), Gaps = 31/197 (15%)

Query: 437 VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEV------- 489
           ++ NL+F I   E VA+VGA+G GK+TL+ L++G +         P SG I++       
Sbjct: 503 IIDNLSFHIKDKESVAIVGATGCGKSTLMSLLMGEL--------TPKSGDIKIAGKIHHS 554

Query: 490 --PKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAVE-VLNRAGLSDAVL-----Y 541
               NA+  +    + +  F    I    +   +  N  VE     AG+ D ++     Y
Sbjct: 555 MAELNARGIIASVNQDDTLFAGSLIENISFFDDKIDNEWVEQCAIMAGIHDEIMAMPMGY 614

Query: 542 RAKFSE----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREA 597
           +    +    LS GQK+R  IA  L  RP +L +DE  +HLD    ++   +++E+++  
Sbjct: 615 QTLVGDMGNVLSGGQKQRIFIARALYRRPKILFLDEATSHLD----VKKEYQINEMIKSL 670

Query: 598 GITAVIITHRPEVVKAL 614
           GIT V+I HRPE ++AL
Sbjct: 671 GITRVMIAHRPERLRAL 687


>sp|P73450|NRTC_SYNY3 NITRATE TRANSPORT ATP-BINDING PROTEIN NRTC >gi|7445984|pir||S77387
           nitrate transport protein C-2 - Synechocystis sp.
           (strain PCC 6803) >gi|1652569|dbj|BAA17490.1| (D90906)
           nitrate transport protein NrtC [Synechocystis sp.]
           Length = 670
           
 Score = 78.8 bits (191), Expect = 2e-13
 Identities = 61/199 (30%), Positives = 98/199 (48%), Gaps = 19/199 (9%)

Query: 438 LRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYW-------EEKYRPTSGKIEVP 490
           L+N+   I+ GE ++++G SG GK+TLL +I G  K  +       +E   P   ++ V 
Sbjct: 25  LKNIELKISQGEFISLIGHSGCGKSTLLNMISGLDKPTFGGVIMEGKEITEPGPERMVVF 84

Query: 491 KNAKVSVLIPGEIEPEFGSETILEHVYR----KIRDLNAAVEVLNRAGLSDAVLYRAKFS 546
           +N  +   +            +L  + +    KI D N A+  L RA          +  
Sbjct: 85  QNYSLLPWLTVRQNIALAVNRVLRDLPKPEQEKIIDDNIALVGLQRAA-------HKRPG 137

Query: 547 ELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITH 606
           ELS G K+R  IA  L+ RP VLL+DE    LD LT   +  ++ EIV+E+G+T +++TH
Sbjct: 138 ELSGGMKQRVAIARALSTRPKVLLLDEPFGALDALTRGNLQERLMEIVQESGVTCIMVTH 197

Query: 607 RPEVVKALDPDKVLFVGYG 625
             +    L  D+V+ +  G
Sbjct: 198 DVDEALLLS-DRVVMLTTG 215


>pir||T37701 probable abc transporter - fission yeast (Schizosaccharomyces
           pombe) (fragment) >gi|2239178|emb|CAB10098.1| (Z97208)
           putative abc transporter [Schizosaccharomyces pombe]
           Length = 467
           
 Score = 78.8 bits (191), Expect = 2e-13
 Identities = 64/218 (29%), Positives = 105/218 (47%), Gaps = 31/218 (14%)

Query: 435 RPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAK 494
           RP+L   +F I  G  VA VGASG GK+T+LRL+           Y   SGKI +  N +
Sbjct: 230 RPILNGCSFNIPAGAKVAFVGASGCGKSTILRLLF--------RFYDTDSGKILID-NQR 280

Query: 495 VSVLIPGEIEPEFG---------SETILEHV-YRKIRDLN-AAVEVLNRAGLSDAVL--- 540
           +  +    +    G         ++TIL ++ Y   +  N   VE   +A + D +    
Sbjct: 281 LDQITLNSLRKAIGVVPQDTPLFNDTILYNIGYGNPKASNDEIVEAAKKAKIHDIIESFP 340

Query: 541 --YRAKFSE----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIV 594
             Y+ K  E    +S G+K+R  ++ LL + P +L  DE  + LDT T   + R +++++
Sbjct: 341 EGYQTKVGERGLMISGGEKQRLAVSRLLLKNPEILFFDEATSALDTNTERALLRNINDLI 400

Query: 595 REAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKS 632
           + +  T+V I HR   +K  D D +  +  G V+ + S
Sbjct: 401 KGSHKTSVFIAHRLRTIK--DCDIIFVLEKGRVVEQGS 436


>pir||E71130 probable oligopeptide transport ATP-binding protein APPD -
           Pyrococcus horikoshii >gi|3257220|dbj|BAA29903.1|
           (AP000003) 327aa long hypothetical oligopeptide
           transport ATP-binding protein APPD [Pyrococcus
           horikoshii]
           Length = 327
           
 Score = 78.8 bits (191), Expect = 2e-13
 Identities = 67/233 (28%), Positives = 111/233 (46%), Gaps = 34/233 (14%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           EI+ L   +  R+  +    L N++F++  G +V ++G SG+GK+TL   IL  +     
Sbjct: 6   EIEGLTVKYKTRYGTVH--ALSNVSFSVKKGSIVGIIGESGSGKSTLGHTILRTLP---- 59

Query: 478 EKYRPTSGKI--------EVPKNA--------KVSVLIPGEIE---PEFGSETILEHVYR 518
           E  R  SGKI        E+ +          K+S++    +    P    +  L  V R
Sbjct: 60  ENARIESGKIMFEGSDLLEIDEEVFRREFRWKKISMIFQNSMNAFSPVHRIQDQLLDVAR 119

Query: 519 KI---RDLNAAVEVLNR----AGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLI 571
           K    +  N  +E++      A + ++VL +    ELS GQ++R  I   L   P +++ 
Sbjct: 120 KCFPNKSRNELLEIIKEKLRIANIDESVLKKYPH-ELSGGQRQRVAIGMALLADPEIVIA 178

Query: 572 DEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPD-KVLFVG 623
           DE    LD +T  ++  ++ EI ++ GIT ++ITH   VV AL  D  VL+ G
Sbjct: 179 DEPTTGLDVVTQYQILNRLKEIQKDLGITLLLITHDVSVVAALSTDVLVLYAG 231


>gb|AAF23272.1|AF101263_2 (AF121672) ABC transporter MreA [Staphylococcus aureus]
           Length = 261
           
 Score = 78.8 bits (191), Expect = 2e-13
 Identities = 62/190 (32%), Positives = 94/190 (48%), Gaps = 16/190 (8%)

Query: 435 RPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIK--------GYWEEKYRPTSGK 486
           + VL N+N  IN GE +A+VG +GAGK+TLL+LILG +         G  + K + TS K
Sbjct: 23  KKVLENINIKINKGEFLAIVGPNGAGKSTLLKLILGLLPLQSGEIFVGGIDFKNKKTSIK 82

Query: 487 ---IEVPKNAKVSVLIPGEIEPEFGSETILEHVYRKI--RDLNAAVEVLNRAGLSDAVLY 541
              +    NA  S       E      T  + +++    +D    ++VL R  +SD  L 
Sbjct: 83  LSYVSQKANAFNSGFPASVKEVVLSGLTKTKRLFQTFNSKDNEKVIKVLERLNISD--LI 140

Query: 542 RAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITA 601
               +ELS GQ++R  IA  L   P VL++DE    +D          + ++ +E GIT 
Sbjct: 141 HKNIAELSGGQQQRVMIARALISEPAVLVLDEPTNGIDAKHVSEFYNTLDQLKQE-GITI 199

Query: 602 VIITHRPEVV 611
           +++TH   VV
Sbjct: 200 ILVTHDIGVV 209


>emb|CAB65561.1| (AL136058) probable amino acid ABC transporter protein, ATP-binding
           component. [Streptomyces coelicolor A3(2)]
           Length = 261
           
 Score = 78.8 bits (191), Expect = 2e-13
 Identities = 69/221 (31%), Positives = 107/221 (48%), Gaps = 16/221 (7%)

Query: 421 DLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKY 480
           +L++   V  R     VL +L+F+++ G+ V ++G SG+GKTT+LRL++  +K   +E  
Sbjct: 19  ELIRLEQVTKRFGDNTVLDHLDFSVDAGKHVTLIGPSGSGKTTILRLLMTLLKP--DEGT 76

Query: 481 RPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEH--VYRKIRDLNAAV------EVLNR 532
               G+   P   K    +  +I   F    +  +  V R I +    V      E + R
Sbjct: 77  ITVDGQKLFPATEKERREVRKQIGMVFQQFNLFPNMSVLRNITEAPVTVLGMPKDEAVER 136

Query: 533 A-GLSDAVLYR----AKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVA 587
           A GL D V       A+ ++LS GQ++R  IA  LA RP VLL+DE  + LD      V 
Sbjct: 137 AKGLLDMVGLADKCDARPAQLSGGQQQRVAIARALAMRPKVLLLDEVTSALDPELVAGVL 196

Query: 588 RKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
             + +I R   IT + +TH     + +  D+VL    G VI
Sbjct: 197 DLLRDIARSTDITMLCVTHEMNFARDIS-DQVLMFDSGRVI 236


>gb|AAF99566.1| (AF167161) unknown [Staphylococcus aureus]
           Length = 309
           
 Score = 78.8 bits (191), Expect = 2e-13
 Identities = 63/218 (28%), Positives = 103/218 (46%), Gaps = 18/218 (8%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIK---- 473
           EI +L K +G +  V       NL+ T+  G++   +G +GAGKTT +R++LG IK    
Sbjct: 9   EINNLTKQYGSQIAV------NNLSITVESGQIYGFLGRNGAGKTTTIRMLLGLIKPTKG 62

Query: 474 --GYWEEKYRPTSGKIEVPKNAKVSVLIPGEIEPEFGSETI-LEHVYRKIRDLNAAVEVL 530
               +E+++   S K E+ KN    V  PG        E + +      I+  NA  EVL
Sbjct: 63  NIKIFEKEFE--SNKTEILKNIGAMVETPGFYSNLTAKENLTINAKILGIQKENAIEEVL 120

Query: 531 NRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKV 590
              GL+   +    F   S G K+R  IA  L   P +L++DE    LD +    + + +
Sbjct: 121 EIVGLASEKV--KLFKNYSLGMKQRLGIARALLHNPELLILDEPTNGLDPIGIKEIRKLI 178

Query: 591 SEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
            ++ +   IT +I +H    ++ L  DKV  +  G ++
Sbjct: 179 KDLAQSRNITILISSHILSEIEQL-VDKVGIIHNGVLL 215


>sp|O14286|YETI_SCHPO PUTATIVE ABC TRANSPORTER C8C9.18 IN CHROMOSOME I
           >gi|11359219|pir||T39154 probable ABC transporter -
           fission yeast  (Schizosaccharomyces pombe)
           Length = 693
           
 Score = 78.8 bits (191), Expect = 2e-13
 Identities = 64/218 (29%), Positives = 105/218 (47%), Gaps = 31/218 (14%)

Query: 435 RPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAK 494
           RP+L   +F I  G  VA VGASG GK+T+LRL+           Y   SGKI +  N +
Sbjct: 456 RPILNGCSFNIPAGAKVAFVGASGCGKSTILRLLF--------RFYDTDSGKILID-NQR 506

Query: 495 VSVLIPGEIEPEFG---------SETILEHV-YRKIRDLN-AAVEVLNRAGLSDAVL--- 540
           +  +    +    G         ++TIL ++ Y   +  N   VE   +A + D +    
Sbjct: 507 LDQITLNSLRKAIGVVPQDTPLFNDTILYNIGYGNPKASNDEIVEAAKKAKIHDIIESFP 566

Query: 541 --YRAKFSE----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIV 594
             Y+ K  E    +S G+K+R  ++ LL + P +L  DE  + LDT T   + R +++++
Sbjct: 567 EGYQTKVGERGLMISGGEKQRLAVSRLLLKNPEILFFDEATSALDTNTERALLRNINDLI 626

Query: 595 REAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKS 632
           + +  T+V I HR   +K  D D +  +  G V+ + S
Sbjct: 627 KGSHKTSVFIAHRLRTIK--DCDIIFVLEKGRVVEQGS 662


>pir||E82539 ABC transporter ATP-binding protein XF2582 [imported] - Xylella
           fastidiosa (strain 9a5c)
           >gi|9107799|gb|AAF85379.1|AE004065_4 (AE004065) ABC
           transporter ATP-binding protein [Xylella fastidiosa]
           Length = 564
           
 Score = 78.4 bits (190), Expect = 2e-13
 Identities = 66/239 (27%), Positives = 115/239 (47%), Gaps = 36/239 (15%)

Query: 415 LPQEIQDLLKAFGVRHRVIQRP---VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGA 471
           LPQ ++  ++   V     QRP    L +++  I PGE +A VG SGAGK+TLL L+L  
Sbjct: 316 LPQPLRGEIRFERVGFHYPQRPETPALDDIDLHIRPGETIAFVGPSGAGKSTLLSLLL-- 373

Query: 472 IKGYWEEKYRPTSGKIEV---------PKNAKVSVLIPGEIEPEFGSETILEHV-YRKIR 521
                   Y PT G+I +         PK  +  + +  + +P   + + +E++ Y ++ 
Sbjct: 374 ------RFYDPTHGRILIDGVDLRQTDPKVLRTHIALVQQ-QPTLFTASAMENIRYGRLD 426

Query: 522 DLNAAVEVLNRAGLSDAVL------YRAKFSE----LSTGQKERAKIASLLAERPNVLLI 571
              A +E+ +R+  +D  +      Y  +  E    LS GQ++R  IA  L +   +LL+
Sbjct: 427 ATTAEIEIASRSSEADGFIRALPQSYATELGEHGMSLSGGQQQRIAIARALLKEAPILLL 486

Query: 572 DEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVR 630
           DE    LD      V + +  ++   G T +II HR  +V  L  D+++ +  G ++ +
Sbjct: 487 DEATNALDAQNEQAVQQALERLM--TGRTTLIIAHR--LVTILKADRIVVMDQGRIVAQ 541


>pir||D69180 ABC transporter - Methanobacterium thermoautotrophicum  (strain
           Delta H) >gi|2621685|gb|AAB85111.1| (AE000842) ABC
           transporter [Methanobacterium thermoautotrophicum]
           Length = 250
           
 Score = 78.4 bits (190), Expect = 2e-13
 Identities = 63/188 (33%), Positives = 96/188 (50%), Gaps = 29/188 (15%)

Query: 435 RPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEV----P 490
           R +LRN+N  +  GE++AV+G +G GKTTLLRLI G IK        PT G + V    P
Sbjct: 18  REILRNINLKVPMGELLAVIGPNGGGKTTLLRLITGQIK--------PTRGTVRVLGMKP 69

Query: 491 KNAKVSV-LIP--GEIEPEFG---SETILEHVYRKIR-----DLNAAVEVLNRAGLSDAV 539
           ++++  +  +P     E +F     +T+L   YR+       D   A+  L   G+ +  
Sbjct: 70  EDSRSRIGYLPQRSHFETDFPINILQTVLIGTYRRFEAPTDDDRKKALRALKMVGMLE-- 127

Query: 540 LYR-AKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAG 598
            YR  K  ELS G+ +R  +A  L   P++LL+DE  A +D        R + E+  E  
Sbjct: 128 -YRDRKIGELSGGELQRVFLARALVREPDLLLLDEPTASVDPAFRGSFYRIIDELRDE-- 184

Query: 599 ITAVIITH 606
           +T VI++H
Sbjct: 185 MTIVIVSH 192


>pir||H82381 toxin secretion ATP-binding protein VCA1084 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9658530|gb|AAF96977.1| (AE004433) toxin secretion
           ATP-binding protein [Vibrio cholerae]
           Length = 704
           
 Score = 78.4 bits (190), Expect = 2e-13
 Identities = 61/211 (28%), Positives = 109/211 (50%), Gaps = 33/211 (15%)

Query: 438 LRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVSV 497
           +R+L+ TI+PGE VA++G  G+GKTTL RLI+G         Y+PT G + +  +  +S 
Sbjct: 486 VRDLSLTIHPGEKVAIIGRIGSGKTTLERLIMGL--------YKPTEGHVRI-DDTDISQ 536

Query: 498 LIPGEIEPEFG---SETILEH--------VYRKIRDLNAAVEVLNRAGLS-----DAVLY 541
           L   +I    G    +++L +        + R + D    ++  NRAG++     D    
Sbjct: 537 LHHIDIRRNIGCVPQDSVLFYGSIRDNITLGRPLSDDREVMDAANRAGVTVFTQQDPAGL 596

Query: 542 RAKFSE----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREA 597
             +  E    LS GQ++   IA     RP VLL+DE  + +D  + M + +++S++  + 
Sbjct: 597 ERQVGEGGMLLSGGQRQSVSIARAFLGRPPVLLMDEPTSAMDNRSEMHIKQQLSQL--KP 654

Query: 598 GITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
             T ++ITH+  ++  +  D+V+ +  G +I
Sbjct: 655 SETLILITHKTSMLDVV--DRVIVMEKGCII 683


>emb|CAB65650.1| (AJ252160) putative ABC-transporter ATP-binding protein
           [Alicyclobacillus acidocaldarius]
           Length = 393
           
 Score = 78.4 bits (190), Expect = 2e-13
 Identities = 69/207 (33%), Positives = 107/207 (51%), Gaps = 30/207 (14%)

Query: 438 LRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVSV 497
           +R ++F I  GE+V ++G SG+GKTT+LRLI G          RPT G + +    +V+ 
Sbjct: 19  VRGVSFQIREGEMVGLLGPSGSGKTTILRLIAGL--------ERPTKGDVWIG-GKRVTD 69

Query: 498 LIPGE--IEPEFGSETILEH--VYRKIR-----------DLNAAVEVLNRAGLSDAVLYR 542
           L P +  +   F +  + +H  VY  +            +++A V  L R    ++  Y 
Sbjct: 70  LPPQKRNVGLVFQNYALFQHMTVYDNVSFGLREKRVPKDEMDARVRELLRFMRLES--YA 127

Query: 543 AKFS-ELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITA 601
            +F  ELS GQ++R  +A  LA RP VLL DE  A +DT     +   V ++  E G+T+
Sbjct: 128 NRFPHELSGGQQQRVALARALAPRPQVLLFDEPFAAIDTQIRRELRTFVRQVHDEMGVTS 187

Query: 602 VIITHRPEVVKALD-PDKVLFVGYGTV 627
           V +TH  E  +AL+  D+VL +  G V
Sbjct: 188 VFVTHDQE--EALEVADRVLVLHEGNV 212


>sp|P44531|AFUC_HAEIN PUTATIVE FERRIC TRANSPORT ATP-BINDING PROTEIN AFUC
           >gi|1074273|pir||D64143 probable ABC-type transport
           protein HI0126 - Haemophilus influenzae (strain Rd KW20)
           >gi|1573081|gb|AAC21800.1| (U32698) ferric ABC
           transporter, ATP-binding protein (afuC) [Haemophilus
           influenzae Rd]
           Length = 328
           
 Score = 78.0 bits (189), Expect = 3e-13
 Identities = 62/228 (27%), Positives = 111/228 (48%), Gaps = 38/228 (16%)

Query: 419 IQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEE 478
           ++++ KAFG      +  V+ NL+ TI  G +V ++G SG GKTT+LRL+ G        
Sbjct: 9   LKNITKAFG------KAVVIDNLDLTIKRGTMVTLLGPSGCGKTTVLRLVAGL------- 55

Query: 479 KYRPTSGKIEVP-KNAKVSVLIPGEIEPEFGSETILEHVY-----------------RKI 520
              PTSG+I +  ++   S +   +I   F S  +  H+                   + 
Sbjct: 56  -ENPTSGQIFIDGEDVTKSSIQNRDICIVFQSYALFPHMSIGDNVGYGLKMQGIGKEERA 114

Query: 521 RDLNAAVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDT 580
           + +  A+E+++ AG  D  +      ++S GQ++R  +A  L  +P VLL DE  ++LD 
Sbjct: 115 QRVKEALELVDLAGFEDRFV-----DQISGGQQQRVALARALVLKPKVLLFDEPLSNLDA 169

Query: 581 LTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
                +  K+ E+ +  GIT++ +TH      A+  D+V+ +  G ++
Sbjct: 170 NLRRSMREKIRELQQRLGITSLYVTHDQTEAFAVS-DEVIVMNKGKIM 216


>pir||B64856 probable ABC-type transport protein ycfV - Escherichia coli
           >gi|1787361|gb|AAC74201.1| (AE000212) putative
           ATP-binding component of a transport system [Escherichia
           coli K12]
           Length = 228
           
 Score = 78.0 bits (189), Expect = 3e-13
 Identities = 62/206 (30%), Positives = 103/206 (49%), Gaps = 37/206 (17%)

Query: 433 IQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKI--EVP 490
           +Q  VL N++F++  GE++A+VG+SG+GK+TLL L+ G           PTSG +     
Sbjct: 15  VQTDVLHNVSFSVGEGEMMAIVGSSGSGKSTLLHLLGGL--------DTPTSGDVIFNGQ 66

Query: 491 KNAKVSVLIPGEIE--------------PEFGSETILEHV-------YRKIRDLNA-AVE 528
             +K+S     E+               P+F   T LE+V        +K  ++N+ A+E
Sbjct: 67  PMSKLSSAAKAELRNQKLGFIYQFHHLLPDF---TALENVAMPLLIGKKKPAEINSRALE 123

Query: 529 VLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVAR 588
           +L   GL     +R   SELS G+++R  IA  L   P ++L DE   +LD   A  + +
Sbjct: 124 MLKAVGLDHRANHRP--SELSGGERQRVAIARALVNNPRLVLADEPTGNLDARNADSIFQ 181

Query: 589 KVSEIVREAGITAVIITHRPEVVKAL 614
            + E+ R  G   +++TH  ++ K +
Sbjct: 182 LLGELNRLQGTAFLVVTHDLQLAKRM 207


>pir||B70483 ABC transporter - Aquifex aeolicus >gi|2984332|gb|AAC07853.1|
           (AE000774) ABC transporter [Aquifex aeolicus]
           Length = 253
           
 Score = 78.0 bits (189), Expect = 3e-13
 Identities = 61/216 (28%), Positives = 113/216 (52%), Gaps = 33/216 (15%)

Query: 435 RPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEV-PKNA 493
           R +L+++NF++  GE+ +++G SG+GKT++ +LI+G         ++PT GK+ V  KN 
Sbjct: 17  RVILKDVNFSVYKGEIFSIIGGSGSGKTSITKLIVGL--------WKPTKGKVLVFRKNV 68

Query: 494 -KVSVLIPGEIEPEFGS--------------ETI----LEHVYRKIRDLNA-AVEVLNRA 533
            ++S L   E+    G               E +    LEH      +L   A+E L   
Sbjct: 69  PELSGLELDELRKNIGYVFQEGALFDSYRVWENVVFYYLEHGKHNKEELRKMALENLKLV 128

Query: 534 GLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEI 593
            + ++VL     SEL  G ++R  IA  +A RP +++ DE  + LD +T+  + + + E+
Sbjct: 129 NVDESVLDLYP-SELFGGMRKRVAIARAIATRPQLIIYDEPTSGLDPITSRVIDKLILEL 187

Query: 594 VREAGITAVIITHRPEVVKALD-PDKVLFVGYGTVI 628
             + G T++++TH  +++ A    D+V+ +  G +I
Sbjct: 188 RNKTGTTSLVVTH--DMISAFTISDRVMVIKNGEII 221


>sp|P75957|YCFV_ECOLI HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN YCFV
           Length = 233
           
 Score = 78.0 bits (189), Expect = 3e-13
 Identities = 62/206 (30%), Positives = 103/206 (49%), Gaps = 37/206 (17%)

Query: 433 IQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKI--EVP 490
           +Q  VL N++F++  GE++A+VG+SG+GK+TLL L+ G           PTSG +     
Sbjct: 20  VQTDVLHNVSFSVGEGEMMAIVGSSGSGKSTLLHLLGGL--------DTPTSGDVIFNGQ 71

Query: 491 KNAKVSVLIPGEIE--------------PEFGSETILEHV-------YRKIRDLNA-AVE 528
             +K+S     E+               P+F   T LE+V        +K  ++N+ A+E
Sbjct: 72  PMSKLSSAAKAELRNQKLGFIYQFHHLLPDF---TALENVAMPLLIGKKKPAEINSRALE 128

Query: 529 VLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVAR 588
           +L   GL     +R   SELS G+++R  IA  L   P ++L DE   +LD   A  + +
Sbjct: 129 MLKAVGLDHRANHRP--SELSGGERQRVAIARALVNNPRLVLADEPTGNLDARNADSIFQ 186

Query: 589 KVSEIVREAGITAVIITHRPEVVKAL 614
            + E+ R  G   +++TH  ++ K +
Sbjct: 187 LLGELNRLQGTAFLVVTHDLQLAKRM 212


>pir||C82266 ABC transporter, ATP-binding protein VC0907 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9655363|gb|AAF94069.1| (AE004174) ABC transporter,
           ATP-binding protein [Vibrio cholerae]
           Length = 344
           
 Score = 78.0 bits (189), Expect = 3e-13
 Identities = 70/232 (30%), Positives = 110/232 (47%), Gaps = 35/232 (15%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           EI+ + K F    + I    L+++N  I  G +  V+G+SGAGK+TL+R +         
Sbjct: 3   EIKSVNKVFYQGDKQIH--ALKDINLFIPQGTIFGVIGSSGAGKSTLIRCV--------N 52

Query: 478 EKYRPTSGKIEVPKNAKVSVLIP---------GEIEPEF---GSETILEHVYRKIRDLNA 525
              +PTSG++ V      ++  P         G I   F    S T+ E+V   +     
Sbjct: 53  MLEKPTSGQVIVDGVDLTTLSNPQLCAARRNIGMIFQHFNLLSSRTVFENVALPLELAGQ 112

Query: 526 A--------VEVLNRAGLSDAVLYRAKF-SELSTGQKERAKIASLLAERPNVLLIDEFAA 576
           +         E+L   GLS+    R  + + LS GQK+R  IA  LA  P VLL DE  +
Sbjct: 113 SQQHIETKVTELLALVGLSEK---RESYPANLSGGQKQRVAIARALASDPKVLLCDEATS 169

Query: 577 HLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
            LD  T   +   + EI R+  +T ++ITH  +VVK++   +V  +G G ++
Sbjct: 170 ALDPATTQSILELLKEINRQLNLTILLITHEMDVVKSI-CHEVAIIGGGELV 220


>dbj|BAA35937.1| (D90747) Heterocyst maturation protein (devA) homolog [Escherichia
           coli]
           Length = 263
           
 Score = 78.0 bits (189), Expect = 3e-13
 Identities = 62/206 (30%), Positives = 103/206 (49%), Gaps = 37/206 (17%)

Query: 433 IQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKI--EVP 490
           +Q  VL N++F++  GE++A+VG+SG+GK+TLL L+ G           PTSG +     
Sbjct: 50  VQTDVLHNVSFSVGEGEMMAIVGSSGSGKSTLLHLLGGL--------DTPTSGDVIFNGQ 101

Query: 491 KNAKVSVLIPGEIE--------------PEFGSETILEHV-------YRKIRDLNA-AVE 528
             +K+S     E+               P+F   T LE+V        +K  ++N+ A+E
Sbjct: 102 PMSKLSSAAKAELRNQKLGFIYQFHHLLPDF---TALENVAMPLLIGKKKPAEINSRALE 158

Query: 529 VLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVAR 588
           +L   GL     +R   SELS G+++R  IA  L   P ++L DE   +LD   A  + +
Sbjct: 159 MLKAVGLDHRANHRP--SELSGGERQRVAIARALVNNPRLVLADEPTGNLDARNADSIFQ 216

Query: 589 KVSEIVREAGITAVIITHRPEVVKAL 614
            + E+ R  G   +++TH  ++ K +
Sbjct: 217 LLGELNRLQGTAFLVVTHDLQLAKRM 242


>sp|Q02592|HMT1_SCHPO HEAVY METAL TOLERANCE PROTEIN PRECURSOR >gi|2370465|emb|CAB11609.1|
           (Z98951) heavy metal tolerance protein precursor
           [Schizosaccharomyces pombe]
           Length = 830
           
 Score = 77.6 bits (188), Expect = 4e-13
 Identities = 69/285 (24%), Positives = 134/285 (46%), Gaps = 64/285 (22%)

Query: 365 EYLERYFKEDPYAPKEPLWKPSYGKVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLK 424
           E L   F+E P   +    KP+   +++ +G ++F +V+  ++                 
Sbjct: 556 ERLLEIFEEKPTVVE----KPNAPDLKVTQGKVIFSHVSFAYDP---------------- 595

Query: 425 AFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTS 484
                    ++PVL ++NF   PG+V+A+VG SG GK+T++R++L          +   S
Sbjct: 596 ---------RKPVLSDINFVAQPGKVIALVGESGGGKSTIMRILL--------RFFDVNS 638

Query: 485 GKIEVP----KNAKVSVL------IPGEIEPEFGSETILEHV-YRKIRDLNAAVEVLNRA 533
           G I +     +N  +S L      +P   +    ++TIL ++ Y K    N  +    +A
Sbjct: 639 GSITIDDQDIRNVTLSSLRSSIGVVPQ--DSTLFNDTILYNIKYAKPSATNEEIYAAAKA 696

Query: 534 G-LSDAVL-----YRAKFSE----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTA 583
             + D +L     Y ++  E    LS G+K+R  +A  + + P+++L+DE  + LDT T 
Sbjct: 697 AQIHDRILQFPDGYNSRVGERGLKLSGGEKQRVAVARAILKDPSIILLDEATSALDTNTE 756

Query: 584 MRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
            ++   ++ +   +G TA++I HR   +   + D +L +  G ++
Sbjct: 757 RQIQAALNRLA--SGRTAIVIAHRLSTI--TNADLILCISNGRIV 797


>pir||T41582 heavy metal tolerance protein precursor - fission yeast
           (Schizosaccharomyces pombe) (fragment)
           >gi|4239675|emb|CAA20865.1| (AL031546) heavy metal
           tolerance protein precursor [Schizosaccharomyces pombe]
           Length = 505
           
 Score = 77.6 bits (188), Expect = 4e-13
 Identities = 69/285 (24%), Positives = 134/285 (46%), Gaps = 64/285 (22%)

Query: 365 EYLERYFKEDPYAPKEPLWKPSYGKVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLK 424
           E L   F+E P   +    KP+   +++ +G ++F +V+  ++                 
Sbjct: 231 ERLLEIFEEKPTVVE----KPNAPDLKVTQGKVIFSHVSFAYDP---------------- 270

Query: 425 AFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTS 484
                    ++PVL ++NF   PG+V+A+VG SG GK+T++R++L          +   S
Sbjct: 271 ---------RKPVLSDINFVAQPGKVIALVGESGGGKSTIMRILL--------RFFDVNS 313

Query: 485 GKIEVP----KNAKVSVL------IPGEIEPEFGSETILEHV-YRKIRDLNAAVEVLNRA 533
           G I +     +N  +S L      +P   +    ++TIL ++ Y K    N  +    +A
Sbjct: 314 GSITIDDQDIRNVTLSSLRSSIGVVPQ--DSTLFNDTILYNIKYAKPSATNEEIYAAAKA 371

Query: 534 G-LSDAVL-----YRAKFSE----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTA 583
             + D +L     Y ++  E    LS G+K+R  +A  + + P+++L+DE  + LDT T 
Sbjct: 372 AQIHDRILQFPDGYNSRVGERGLKLSGGEKQRVAVARAILKDPSIILLDEATSALDTNTE 431

Query: 584 MRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
            ++   ++ +   +G TA++I HR   +   + D +L +  G ++
Sbjct: 432 RQIQAALNRLA--SGRTAIVIAHRLSTI--TNADLILCISNGRIV 472


>pir||A82184 ABC transporter, ATP-binding protein VC1568 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9656076|gb|AAF94722.1| (AE004234) ABC transporter,
           ATP-binding protein [Vibrio cholerae]
           Length = 233
           
 Score = 77.6 bits (188), Expect = 4e-13
 Identities = 59/209 (28%), Positives = 107/209 (50%), Gaps = 20/209 (9%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E+Q + K +     V++   L  ++ TI  GE +A++G SG+GK+TL+  +LG +     
Sbjct: 11  ELQQICKHYTSGQNVVK--ALDGVDLTIRHGEFLAILGPSGSGKSTLMN-VLGCLDKPTA 67

Query: 478 EKYRPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEH-----------VYRKIRDLNA- 525
            +Y+     ++     +++ +   +I   F S  +LE+           VY  ++  +  
Sbjct: 68  GRYQLDGHPVDSLSTQQLAAIRNQKIGFVFQSFNLLEYASALDNVALPLVYAGVKAKDRR 127

Query: 526 --AVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTA 583
             A E+L R GL+D + ++   ++LS GQK+R  IA  L  +P +LL DE    LD+ + 
Sbjct: 128 RRATELLTRVGLADRLDHKP--NQLSGGQKQRVAIARALINQPQILLADEPTGALDSKSG 185

Query: 584 MRVARKVSEIVREAGITAVIITHRPEVVK 612
             +    +E+ RE G T +++TH  E+ K
Sbjct: 186 AEIEALFNELHRE-GRTIIVVTHDNELAK 213


>pir||S25198 vacuolar membrane protein HMT1 - fission yeast
           (Schizosaccharomyces pombe) >gi|4972|emb|CAA78419.1|
           (Z14055) HMT1 [Schizosaccharomyces pombe]
           Length = 830
           
 Score = 77.6 bits (188), Expect = 4e-13
 Identities = 69/285 (24%), Positives = 134/285 (46%), Gaps = 64/285 (22%)

Query: 365 EYLERYFKEDPYAPKEPLWKPSYGKVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLK 424
           E L   F+E P   +    KP+   +++ +G ++F +V+  ++                 
Sbjct: 556 ERLLEIFEEKPTVVE----KPNAPDLKVTQGKVIFSHVSFAYDP---------------- 595

Query: 425 AFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTS 484
                    ++PVL ++NF   PG+V+A+VG SG GK+T++R++L          +   S
Sbjct: 596 ---------RKPVLSDINFVAQPGKVIALVGESGGGKSTIMRILL--------RFFDVNS 638

Query: 485 GKIEVP----KNAKVSVL------IPGEIEPEFGSETILEHV-YRKIRDLNAAVEVLNRA 533
           G I +     +N  +S L      +P   +    ++TIL ++ Y K    N  +    +A
Sbjct: 639 GSITIDDQDIRNVTLSSLRSSIGVVPQ--DSTLFNDTILYNIKYAKPSATNEEIYAAAKA 696

Query: 534 G-LSDAVL-----YRAKFSE----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTA 583
             + D +L     Y ++  E    LS G+K+R  +A  + + P+++L+DE  + LDT T 
Sbjct: 697 AQIHDRILQFPDGYNSRVGERGLKLSGGEKQRVAVARAILKDPSIILLDEATSALDTNTE 756

Query: 584 MRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
            ++   ++ +   +G TA++I HR   +   + D +L +  G ++
Sbjct: 757 RQIQAALNRLA--SGRTAIVIAHRLSTI--TNADLILCISNGRIV 797


>sp|Q06034|MDR1_LEIEN MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN 1)
           >gi|159370|gb|AAA16255.1| (L08091) multidrug resistance
           protein [Leishmania enriettii]
           Length = 1280
           
 Score = 77.6 bits (188), Expect = 4e-13
 Identities = 70/251 (27%), Positives = 121/251 (47%), Gaps = 39/251 (15%)

Query: 398 VFKNVTKVFESELDIKGLPQE-IQDLLKAFGVRHRVIQRP---VLRNLNFTINPGEVVAV 453
           +FK + +V   ++D  G+P    ++ ++   VR     RP   + R+L+  I  G+ VA 
Sbjct: 365 IFKAIDRVPPVDIDAGGVPVPGFKESIEFRNVRFAYPTRPGMILFRDLSLKIKCGQKVAF 424

Query: 454 VGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVP---------KNAKVSVLIPGEIE 504
            GASG GK++++ LI        +  Y P  G + V          +  +  + I  + E
Sbjct: 425 SGASGCGKSSVIGLI--------QRFYDPIGGAVLVDGVRMRELCLREWRDQIGIVSQ-E 475

Query: 505 PEFGSETILEHVYRKIRDLNAA----VEVLNRAGLSDAVL-----YRAKF----SELSTG 551
           P   + T++E+V  ++   NA     VE   +A + D ++     Y        S LS G
Sbjct: 476 PNLFAGTMMENV--RMGKPNATDEEVVEACRQANIHDTIMALPDRYDTPVGPVGSLLSGG 533

Query: 552 QKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVV 611
           QK+R  IA  L +RP +LL+DE  + LD  + M V   + ++++  G T V+I HR   +
Sbjct: 534 QKQRIAIARALVKRPPILLLDEATSALDRKSEMEVQAALDQLIQRGGTTVVVIAHRLATI 593

Query: 612 KALDPDKVLFV 622
           +  D D++ +V
Sbjct: 594 R--DMDRIYYV 602


>sp|Q57293|AFUC_ACTPL FERRIC TRANSPORT ATP-BINDING PROTEIN AFUC
           >gi|1469284|gb|AAB05030.1| (U05042) afuC gene product
           [Actinobacillus pleuropneumoniae]
           >gi|1477453|gb|AAB17216.1| (U04954) afuC [Actinobacillus
           pleuropneumoniae]
           Length = 348
           
 Score = 77.6 bits (188), Expect = 4e-13
 Identities = 63/229 (27%), Positives = 114/229 (49%), Gaps = 40/229 (17%)

Query: 419 IQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEE 478
           ++++ K+FG      +  V+ NL+  I  G +V ++G SG GKTT+LRL+ G        
Sbjct: 8   LKNITKSFG------KATVIDNLDLVIKRGTMVTLLGPSGCGKTTVLRLVAGL------- 54

Query: 479 KYRPTSGKIEVP-KNAKVSVLIPGEIEPEFGSETILEHVY------------------RK 519
              PTSG+I +  ++   S +   +I   F S  +  H+                   RK
Sbjct: 55  -ENPTSGQIFIDGEDVTKSSIQNRDICIVFQSYALFPHMSIGDNVGYGLRMQGVSNEERK 113

Query: 520 IRDLNAAVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLD 579
            R +  A+E+++ AG +D  +      ++S GQ++R  +A  L  +P VL++DE  ++LD
Sbjct: 114 QR-VKEALELVDLAGFADRFV-----DQISGGQQQRVALARALVLKPKVLILDEPLSNLD 167

Query: 580 TLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
                 +  K+ E+ +  GIT++ +TH      A+  D+V+ +  GT++
Sbjct: 168 ANLRRSMREKIRELQQRLGITSLYVTHDQTEAFAVS-DEVIVMNKGTIM 215


>sp|P75370|P29_MYCPN PROBABLE ABC TRANSPORTER ATP-BINDING PROTEIN P29
           >gi|2146075|pir||S73750 ATP-binding protein P29 -
           Mycoplasma pneumoniae (strain ATCC 29342)
           >gi|1674109|gb|AAB96072.1| (AE000041) ATP-binding
           protein P29 [Mycoplasma pneumoniae]
           Length = 244
           
 Score = 77.3 bits (187), Expect = 5e-13
 Identities = 53/191 (27%), Positives = 87/191 (44%), Gaps = 19/191 (9%)

Query: 436 PVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGA---IKG--YWEEKYRPTSGKIEVP 490
           P+L N+NFTI+PGE + ++G SG GKT+LL  I       KG  Y+           ++ 
Sbjct: 19  PLLENINFTISPGEHICLLGKSGVGKTSLLNCITNTKTISKGTIYFNGIASNNKDYKQLK 78

Query: 491 KNAKVSVLIPGEIEPEFGSETILEHVYRKIR------------DLNAAVEVLNRAGLSDA 538
           K       +P  I+ +F  + I       ++                 +++L    L + 
Sbjct: 79  KQFSFLDQVPNLIDTDFVYDAIWREAKNNLKWWQRLFLVEPQSLREQIIQILEEVNLKEY 138

Query: 539 VLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAG 598
           V Y  K  +LS GQK+R ++A L      VLL+DE    LD + A ++   + +  R+  
Sbjct: 139 VTYIIK--DLSGGQKQRVEVAKLFFANSQVLLVDEPTTGLDLINAHKIMELIIQFARQKA 196

Query: 599 ITAVIITHRPE 609
           +T + +TH  E
Sbjct: 197 MTLIFVTHDVE 207


>pir||D69068 methyl coenzyme M reductase system, component A2 homolog -
           Methanobacterium thermoautotrophicum (strain Delta H)
           >gi|2621192|gb|AAB84657.1| (AE000803) methyl coenzyme M
           reductase system, component A2 homolog [Methanobacterium
           thermoautotrophicum]
           Length = 590
           
 Score = 77.3 bits (187), Expect = 5e-13
 Identities = 62/215 (28%), Positives = 106/215 (48%), Gaps = 28/215 (13%)

Query: 438 LRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKN----A 493
           L ++N  +  GE++ ++G SG+GKTTLLR++ G ++ +   +       +E   +    +
Sbjct: 44  LSDVNLEVAEGEILGILGMSGSGKTTLLRILRG-VEPFDSGRITLDDVTVEADSSQYYFS 102

Query: 494 KVSVLIPGEIEPEFG--SETILEHVYRKIRDLNA------------------AVEVLNRA 533
           K+       ++  FG  +ET LE+V RK+                       A+E+L   
Sbjct: 103 KLKKKTAIHLQRSFGLWAETALENVIRKLYATRYGDESMTDFDYASDEFGEDAMELLRVV 162

Query: 534 GLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEI 593
           GL     + A    LS G+K+R  +A  LA++P VLL+DE A      T   +   +  I
Sbjct: 163 GLEHKADHFAPV--LSGGEKQRLIMARQLAKKPRVLLLDEPATMSCPRTKQEILDAIKNI 220

Query: 594 VREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
            RE G+T V+++H PEV + L  D+V+ +  G ++
Sbjct: 221 NRELGVTVVLVSHLPEVHEYL-ADRVVLMDGGRIV 254


>pir||T36053 probable ABC-type transport protein cydCD - Streptomyces coelicolor
           >gi|3928723|emb|CAA22219.1| (AL034355) putative ABC
           transporter [Streptomyces coelicolor A3(2)]
           Length = 1172
           
 Score = 77.3 bits (187), Expect = 5e-13
 Identities = 74/246 (30%), Positives = 113/246 (45%), Gaps = 36/246 (14%)

Query: 394 EGPIVFKNVTKVFESELDIKGL-PQEIQDLLKAFGVRHRVIQRP--VLRNLNFTINPGEV 450
           EG    +++  V E  +   G  P      L+  GV  R   R    + N++FT+ PGE 
Sbjct: 303 EGLAAAEDIFSVLERPVPASGTGPVPADHALRFEGVTVRYPGRAEAAVTNVDFTVEPGET 362

Query: 451 VAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVSVLIPG--------E 502
           VA+VG SGAGK+TLL  +LG +         PT G++ V      S+ +           
Sbjct: 363 VALVGPSGAGKSTLLNALLGFVP--------PTGGRVRVGGADLASLDVAQWHARVAWVP 414

Query: 503 IEPEFGSETILEH------------VYRKIRDLNAAVEVLNRAGLSDAVLYRAKFSELST 550
             P   + TI E+            V R +RD   A+E ++      A +     + LS 
Sbjct: 415 QHPHLYAGTIAENVRLARPDADDTAVRRALRDA-GALEFVDALPEGTATVLGEDGTGLSA 473

Query: 551 GQKERAKIA-SLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPE 609
           GQ++R  +A + LA+RP VLL+DE  A LD  T   V   V  + +  G T +++ HRP 
Sbjct: 474 GQRQRLALARAFLADRP-VLLLDEPTAALDGATEAEVVDAVRRLAQ--GRTVLLVVHRPA 530

Query: 610 VVKALD 615
           +++  D
Sbjct: 531 LLEVAD 536


>dbj|BAB03891.1| (AP001507) amino acid ABC transporter (ATP-binding protein)
           [Bacillus halodurans]
           Length = 247
           
 Score = 77.3 bits (187), Expect = 5e-13
 Identities = 71/237 (29%), Positives = 113/237 (46%), Gaps = 44/237 (18%)

Query: 419 IQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEE 478
           +Q L K FG      +  VL+ L+ T+  G+VV V+G SG+GKTTLLR +          
Sbjct: 4   VQSLYKKFG------EVEVLKGLDLTVERGKVVVVIGPSGSGKTTLLRCL--------NI 49

Query: 479 KYRPTSGKIEVPK-----NAKVSV-------LIPGEIEPE---FGSETILEHVYR----- 518
              PTSG +++       + KVS         + G +      F   T+L++V       
Sbjct: 50  LETPTSGSVQIENQTLDFSGKVSSKEIANFRRLTGMVFQSYNLFPHMTVLQNVMEGPMTV 109

Query: 519 ----KIRDLNAAVEVLNRAGLSD-AVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDE 573
               K +    A ++L + GL+D   +Y     +LS GQ++R  IA  LA  P V+L DE
Sbjct: 110 KKEAKAQVEEKAKQLLAKVGLADKETVYP---FQLSGGQQQRVGIARALAMEPKVMLFDE 166

Query: 574 FAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVR 630
             + LD      V R + E+  E G+T +++TH     + +  D+V+F+  G ++ R
Sbjct: 167 PTSALDPELVGEVLRVMKELAEE-GMTMIVVTHEMRFAQEV-ADEVIFMDDGKIVER 221


>dbj|BAB11402.1| (AP002543) ABC transporter-like protein [Arabidopsis thaliana]
           Length = 567
           
 Score = 77.3 bits (187), Expect = 5e-13
 Identities = 59/209 (28%), Positives = 107/209 (50%), Gaps = 14/209 (6%)

Query: 433 IQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIK-----GYWEEKYRPTSG-- 485
           +++ +L  ++ ++NPGEV+A++G SG+GKTTLL L+ G I      G      +P S   
Sbjct: 51  VEKEILTGISGSVNPGEVLALMGPSGSGKTTLLSLLAGRISQSSTGGSVTYNDKPYSKYL 110

Query: 486 KIEVPKNAKVSVLIPGEIEPE---FGSETILEHVYRKIRDLNAAVEVLNRAGL---SDAV 539
           K ++    +  VL P     E   + +   L     + +    A++V+   GL    D +
Sbjct: 111 KSKIGFVTQDDVLFPHLTVKETLTYAARLRLPKTLTREQKKQRALDVIQELGLERCQDTM 170

Query: 540 LYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGI 599
           +  A    +S G+++R  I + +   P++LL+DE  + LD+ TA+R    + +I  EAG 
Sbjct: 171 IGGAFVRGVSGGERKRVSIGNEIIINPSLLLLDEPTSGLDSTTALRTILMLHDIA-EAGK 229

Query: 600 TAVIITHRPEVVKALDPDKVLFVGYGTVI 628
           T +   H+P        DK++ +G G+++
Sbjct: 230 TVITTIHQPSSRLFHRFDKLILLGRGSLL 258


>sp|P34712|MDR1_CAEEL MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN A)
            >gi|283551|pir||S27337 multidrug resistance protein A -
            Caenorhabditis elegans >gi|6809|emb|CAA46190.1| (X65054)
            P-glycoprotein A [Caenorhabditis elegans]
            Length = 1321
            
 Score = 76.9 bits (186), Expect = 6e-13
 Identities = 73/270 (27%), Positives = 129/270 (47%), Gaps = 40/270 (14%)

Query: 385  PSYGKVEMLEGPIVFKNVTKVFESE-LDIKGLPQEIQDLLKAFGVRHRVIQRP---VLRN 440
            P Y K     G I+F  + K+ + + L + G  +++   +    VR    +RP   +L+ 
Sbjct: 1039 PEYAKATFAGG-IIFGMLRKISKIDSLSLAGEKKKLYGKVIFKNVRFAYPERPEIEILKG 1097

Query: 441  LNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEV---------PK 491
            L+F++ PG+ +A+VG SG GK+T++ L+        E  Y    G+I +         P+
Sbjct: 1098 LSFSVEPGQTLALVGPSGCGKSTVVALL--------ERFYDTLGGEIFIDGSEIKTLNPE 1149

Query: 492  NAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAV-EVLNRAGLSDAVLYRAKFSE--- 547
            + +  + I  + EP     +I E++   +   +  + +V   A L++   + A+  E   
Sbjct: 1150 HTRSQIAIVSQ-EPTLFDCSIAENIIYGLDPSSVTMAQVEEAARLANIHNFIAELPEGFE 1208

Query: 548  ---------LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAG 598
                     LS GQK+R  IA  L   P +LL+DE  + LDT  + +V ++  +  RE G
Sbjct: 1209 TRVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDT-ESEKVVQEALDRARE-G 1266

Query: 599  ITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
             T ++I HR   V  ++ D +  V  GT+I
Sbjct: 1267 RTCIVIAHRLNTV--MNADCIAVVSNGTII 1294


>pir||S25576 probable transport protein mt2 - rat >gi|407479|emb|CAA53054.1|
           (X75306) TAP2 [Rattus norvegicus]
           Length = 703
           
 Score = 76.9 bits (186), Expect = 6e-13
 Identities = 67/236 (28%), Positives = 115/236 (48%), Gaps = 38/236 (16%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E QD+  ++  R    ++PVL+ L FT++PG+V A+VG +G+GK+T+  L+        +
Sbjct: 469 EFQDVSFSYPSRP---EKPVLQGLTFTLHPGKVTALVGPNGSGKSTVAALL--------Q 517

Query: 478 EKYRPTSGKIEVPKNAKV---------SVLIPGEIEPEFGSETILEHVYRKIRDL-NAAV 527
             Y+PT GK+ +     V          V++ G+ EP   S ++ +++   +RD  +A V
Sbjct: 518 NLYQPTGGKVLLDGEPLVQYDHHYLHRQVVLVGQ-EPVLFSGSVKDNIAYGLRDCEDAQV 576

Query: 528 EVLNRAGLSDAVL----------YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAH 577
               +A  +D  +             K S+L+ GQK+R  IA  L   P VL++DE  + 
Sbjct: 577 MAAAQAACADDFIGEMTNGINTEIGEKGSQLAVGQKQRLAIARALVRNPRVLILDEATSA 636

Query: 578 LDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
           LD      +    S+  R    T ++I HR   V+  + D+VL +  G ++    L
Sbjct: 637 LDAECEQALQTWRSQEDR----TMLVIAHRLHTVQ--NADQVLVLKQGQLVEHDQL 686


>pir||S38402 probable transport protein mt2 - rat >gi|407481|emb|CAA53055.1|
           (X75307) TAP2 [Rattus norvegicus]
           Length = 703
           
 Score = 76.9 bits (186), Expect = 6e-13
 Identities = 67/236 (28%), Positives = 115/236 (48%), Gaps = 38/236 (16%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E QD+  ++  R    ++PVL+ L FT++PG+V A+VG +G+GK+T+  L+        +
Sbjct: 469 EFQDVSFSYPSRP---EKPVLQGLTFTLHPGKVTALVGPNGSGKSTVAALL--------Q 517

Query: 478 EKYRPTSGKIEVPKNAKV---------SVLIPGEIEPEFGSETILEHVYRKIRDL-NAAV 527
             Y+PT GK+ +     V          V++ G+ EP   S ++ +++   +RD  +A V
Sbjct: 518 NLYQPTGGKVLLDGEPLVQYDHHYLHRQVVLVGQ-EPVLFSGSVKDNIAYGLRDCEDAQV 576

Query: 528 EVLNRAGLSDAVL----------YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAH 577
               +A  +D  +             K S+L+ GQK+R  IA  L   P VL++DE  + 
Sbjct: 577 MAAAQAACADDFIGEMTNGINTEIGEKGSQLAVGQKQRLAIARALVRNPRVLILDEATSA 636

Query: 578 LDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
           LD      +    S+  R    T ++I HR   V+  + D+VL +  G ++    L
Sbjct: 637 LDAECEQALQTWRSQEDR----TMLVIAHRLHTVQ--NADQVLVLKQGQLVEHDQL 686


>sp|Q50294|Y179_MYCPN HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MG179 HOMOLOG
           (GT9_ORF274) >gi|2127637|pir||S62815 sulfate transport
           ATP-binding protein cysA - Mycoplasma pneumoniae (strain
           ATCC 29342) >gi|2146659|pir||S73964 sulfate transport
           ATP-binding protein cysA - Mycoplasma pneumoniae (SGC3)
           (ATCC 29342) >gi|1215695|gb|AAC43688.1| (U34795) peptide
           transport system protein SapF homolog; SapF homolog
           [Mycoplasma pneumoniae] >gi|1674343|gb|AAB96286.1|
           (AE000061) cobalt transport ATP-binding protein
           [Mycoplasma pneumoniae]
           Length = 274
           
 Score = 76.9 bits (186), Expect = 6e-13
 Identities = 66/226 (29%), Positives = 108/226 (47%), Gaps = 43/226 (19%)

Query: 427 GVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGK 486
           GV     + P++RNL+F +  GE V +VG +G+GK+T+ +L+ G +K        P +G 
Sbjct: 14  GVYFSYSELPLIRNLSFDVFEGEYVCIVGHNGSGKSTISKLLTGLLK--------PQAGT 65

Query: 487 IEV-----------------------PKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDL 523
           I++                       P N  + + +  +I   FG E      Y + +  
Sbjct: 66  IKIFGKTISSENVTYLRNHIGIIFQNPDNQFIGITVEDDI--AFGLE---NRRYTREKMK 120

Query: 524 NAAVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTA 583
           +   +V  +AG+++  L + +   LS GQK+R  IAS+LA  P +++ DE  + LD   A
Sbjct: 121 SIIEDVAQQAGITE--LLQKEPHNLSGGQKQRVAIASVLALNPAIIIFDESTSMLDP-KA 177

Query: 584 MRVARKVSEIVREAGITAVIITH-RPEVVKALDPDKVLFVGYGTVI 628
            R  ++    +R  G   + ITH   EV KA   DKVL +  G +I
Sbjct: 178 KRTIKQFMVELRNQGKCVISITHDMEEVTKA---DKVLVMNEGRLI 220


>sp|Q9ZCM4|Y700_RICPR HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN RP700
           >gi|7445755|pir||F71676 glutamine transport ATP-binding
           protein glnQ (glnQ1) RP700 - Rickettsia prowazekii
           >gi|3861236|emb|CAA15136.1| (AJ235272) GLUTAMINE
           TRANSPORT ATP-BINDING PROTEIN GLNQ (glnQ1) [Rickettsia
           prowazekii]
           Length = 221
           
 Score = 76.9 bits (186), Expect = 6e-13
 Identities = 62/195 (31%), Positives = 99/195 (49%), Gaps = 26/195 (13%)

Query: 437 VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVP-----K 491
           VL  LN T N GE++A++G+SG+GK+TLL  I G +        +PT+G++ +P     K
Sbjct: 24  VLDGLNLTANEGELIAIIGSSGSGKSTLLH-IAGLLD-------KPTNGQVIIPNIKYKK 75

Query: 492 NAKVSVLIPGEIEPE---FGSETILEHVY--RKIRDLNA------AVEVLNRAGLSDAVL 540
              + +   G I  +       T LE+V   R IR L+       A ++L+  GL +  L
Sbjct: 76  YHLIRLYYLGFIYQQHHLLKDFTALENVIIPRLIRGLDQKEAIKDATKILDDLGL-EKKL 134

Query: 541 YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGIT 600
           Y     ELS G+++R  IA  L  +P ++L DE   +LD  T   V     ++ R+   T
Sbjct: 135 YNMP-GELSGGEQQRVAIARSLINKPRIILADEPTGNLDPNTTNEVFNLFLKVARKQNTT 193

Query: 601 AVIITHRPEVVKALD 615
            +++TH  E+   +D
Sbjct: 194 VIMVTHNHELAHKMD 208


>pir||T18940 multidrug resistance protein homolog - Caenorhabditis elegans
           >gi|3874031|emb|CAA94203.1| (Z70265) Similarity to
           C.elegans p-glycoprotein (SW:MDR1_CAEEL), contains
           similarity to Pfam domain: PF00005 (ABC transporter),
           Score=418.0, E-value=2.8e-122, N=2; PF00664 (ABC
           transporter transmembrane region.), Score=177.0,
           E-value=9.8e-50, N=2~cDNA > >gi|3880013|emb|CAA94221.1|
           (Z70268) Similarity to C.elegans p-glycoprotein
           (SW:MDR1_CAEEL), contains similarity to Pfam domain:
           PF00005 (ABC transporter), Score=418.0,
           E-value=2.8e-122, N=2; PF00664 (ABC transporter
           transmembrane region.), Score=177.0, E-value=9.8e-50,
           N=2~cDNA >
           Length = 1238
           
 Score = 76.9 bits (186), Expect = 6e-13
 Identities = 71/237 (29%), Positives = 115/237 (47%), Gaps = 46/237 (19%)

Query: 419 IQDLLKAFGVRHRVIQRP---VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGY 475
           IQ +L    V+     RP   +LR ++F +  GE +A+VGASG+GK+T+++L+L      
Sbjct: 376 IQGMLSFNNVKFAYPSRPDVDILRGISFDVKQGECIALVGASGSGKSTIVQLLL------ 429

Query: 476 WEEKYRPTSGKIEVP---------KNAKVSVLIPGEIEPEFGSETILEH----------- 515
               Y   SG I++          K  + ++ +  + EP   + TI E+           
Sbjct: 430 --HFYNIQSGTIKIGDSHLHDINLKQLRNAIGVVSQ-EPVLFNTTIEENIRFGNPNATSS 486

Query: 516 -VYRKIRDLNAAVEVLN-RAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDE 573
            +Y  +R  NA   V N + GL   V  R   ++LS GQK+R  IA +L + P +LL+DE
Sbjct: 487 EIYEALRKANAYDFVCNIKDGLKTIVGERG--AQLSGGQKQRIAIARVLVKNPAILLLDE 544

Query: 574 FAAHLDTLTAMRV---ARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTV 627
             + LD+ +   V    +K SE     G T +II HR   ++    DK++ +  G +
Sbjct: 545 ATSALDSASERAVQLALKKASE-----GRTTIIIAHRLSTIRHC--DKIMVMSNGKI 594


>pir||T23476 hypothetical protein K08E7.9 - Caenorhabditis elegans
            >gi|3878418|emb|CAB01232.1| (Z77666) Similarity to
            C.elegans multidrug resistance protein (SW:MDR1_CAEEL),
            contains similarity to Pfam domain: PF00005 (ABC
            transporter), Score=440.3, E-value=5.6e-129, N=2; PF00664
            (ABC transporter transmembrane region.), Score=494.7,
            E-value=2.2e>
            Length = 1321
            
 Score = 76.9 bits (186), Expect = 6e-13
 Identities = 73/270 (27%), Positives = 129/270 (47%), Gaps = 40/270 (14%)

Query: 385  PSYGKVEMLEGPIVFKNVTKVFESE-LDIKGLPQEIQDLLKAFGVRHRVIQRP---VLRN 440
            P Y K     G I+F  + K+ + + L + G  +++   +    VR    +RP   +L+ 
Sbjct: 1039 PEYAKATFAGG-IIFGMLRKISKIDSLSLAGEKKKLYGKVIFKNVRFAYPERPEIEILKG 1097

Query: 441  LNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEV---------PK 491
            L+F++ PG+ +A+VG SG GK+T++ L+        E  Y    G+I +         P+
Sbjct: 1098 LSFSVEPGQTLALVGPSGCGKSTVVALL--------ERFYDTLGGEIFIDGSEIKTLNPE 1149

Query: 492  NAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAV-EVLNRAGLSDAVLYRAKFSE--- 547
            + +  + I  + EP     +I E++   +   +  + +V   A L++   + A+  E   
Sbjct: 1150 HTRSQIAIVSQ-EPTLFDCSIAENIIYGLDPSSVTMAQVEEAARLANIHNFIAELPEGFE 1208

Query: 548  ---------LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAG 598
                     LS GQK+R  IA  L   P +LL+DE  + LDT  + +V ++  +  RE G
Sbjct: 1209 TRVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDT-ESEKVVQEALDRARE-G 1266

Query: 599  ITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
             T ++I HR   V  ++ D +  V  GT+I
Sbjct: 1267 RTCIVIAHRLNTV--MNADCIAVVSNGTII 1294


>sp|Q00449|MDR4_DROME MULTIDRUG RESISTANCE PROTEIN HOMOLOG 49 (P-GLYCOPROTEIN 49)
           >gi|103251|pir||A41249 multidrug resistance protein
           homolog Mdr49 - fruit fly  (Drosophila melanogaster)
           >gi|157871|gb|AAA28679.1| (M59076) P glycoprotein
           [Drosophila melanogaster]
           Length = 1302
           
 Score = 76.5 bits (185), Expect = 9e-13
 Identities = 68/242 (28%), Positives = 114/242 (47%), Gaps = 37/242 (15%)

Query: 410 LDIKG-LPQEIQDLLKAFGVRHRVIQRP---VLRNLNFTINPGEVVAVVGASGAGKTTLL 465
           +D KG  P+     ++  G+R R   RP   +L+ L   + PG+ VA VGASG GK+TL+
Sbjct: 388 MDEKGNRPENTAGHIRFEGIRFRYPARPDVEILKGLTVDVLPGQTVAFVGASGCGKSTLI 447

Query: 466 RLILGAIKGYWEEKYRPTSGKIEVPKN---------AKVSVLIPGEIEPEFGSETILEHV 516
           +L+        +  Y P +G +++             +  + + G+ EP   + TI E++
Sbjct: 448 QLM--------QRFYDPEAGSVKLDGRDLRTLNVGWLRSQIGVVGQ-EPVLFATTIGENI 498

Query: 517 -YRKIRDLNAAVEVLNRAGLSDAVLYRA----------KFSELSTGQKERAKIASLLAER 565
            Y +     A +E   RA      + R           K +++S GQK+R  IA  L  +
Sbjct: 499 RYGRPSATQADIEKAARAANCHDFITRLPKGYDTQVGEKGAQISGGQKQRIAIARALVRQ 558

Query: 566 PNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYG 625
           P VLL+DE  + LD  +  RV   +   +   G T +++ HR   +   + DK++F+  G
Sbjct: 559 PQVLLLDEATSALDPTSEKRVQSALE--LASQGPTTLVVAHRLSTI--TNADKIVFLKDG 614

Query: 626 TV 627
            V
Sbjct: 615 VV 616


 Score = 74.9 bits (181), Expect = 3e-12
 Identities = 74/266 (27%), Positives = 113/266 (41%), Gaps = 56/266 (21%)

Query: 371  FKEDPYAPKEPLWKPSYGKVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRH 430
            FK     P  P  +  Y  VE  EG IV++NV   + +    KG                
Sbjct: 1035 FKRTSTQPNPP--QSPYNTVEKSEGDIVYENVGFEYPTR---KG---------------- 1073

Query: 431  RVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKI--- 487
                 P+L+ LN TI     VA+VG SG+GK+T ++L+L          Y P SG +   
Sbjct: 1074 ----TPILQGLNLTIKKSTTVALVGPSGSGKSTCVQLLL--------RYYDPVSGSVNLS 1121

Query: 488  -----EVPKNAKVSVLIPGEIEPEFGSETILEHV-----YRKIRDLNAAVEVLNRAGLSD 537
                 E P +   S L     EP     TI E++     +R    +   +E   ++ + +
Sbjct: 1122 GVPSTEFPLDTLRSKLGLVSQEPVLFDRTIAENIAYGNNFRDDVSMQEIIEAAKKSNIHN 1181

Query: 538  AV--------LYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARK 589
             +            K S+LS GQK+R  IA  L   P +L++DE  + LD L + +V ++
Sbjct: 1182 FISALPQGYDTRLGKTSQLSGGQKQRIAIARALVRNPKILILDEATSALD-LESEKVVQQ 1240

Query: 590  VSEIVREAGITAVIITHRPEVVKALD 615
              +  R +G T + I HR   V+  D
Sbjct: 1241 ALDEAR-SGRTCLTIAHRLTTVRNAD 1265


>sp|P31134|POTG_ECOLI PUTRESCINE TRANSPORT ATP-BINDING PROTEIN POTG
           >gi|321862|pir||B45313 putrescine transport protein potG
           - Escherichia coli >gi|147335|gb|AAA24410.1| (M93239)
           nucleotide binding protein [Escherichia coli]
           >gi|1651388|dbj|BAA35566.1| (D90723) Putrescine
           transport protein PotG. [Escherichia coli]
           >gi|1787079|gb|AAC73942.1| (AE000187) ATP-binding
           component of putrescine transport system [Escherichia
           coli K12]
           Length = 404
           
 Score = 76.5 bits (185), Expect = 9e-13
 Identities = 60/206 (29%), Positives = 106/206 (51%), Gaps = 29/206 (14%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           EI++L K++  +H V       +++ TI  GE+ A++GASG GK+TLLR++ G       
Sbjct: 48  EIRNLTKSYDGQHAV------DDVSLTIYKGEIFALLGASGCGKSTLLRMLAGF------ 95

Query: 478 EKYRPTSGKIEVPKNAKVSVLIP--GEIEPEFGSETILEHV-------YRKIRDLNAAVE 528
              +P++G+I +     +S + P    I   F S  +  H+       +   +D     E
Sbjct: 96  --EQPSAGQIMLD-GVDLSQVPPYLRPINMMFQSYALFPHMTVEQNIAFGLKQDKLPKAE 152

Query: 529 VLNRAGLSDAVLYRAKFS-----ELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTA 583
           + +R      +++  +F+     +LS GQ++R  +A  LA+RP +LL+DE    LD    
Sbjct: 153 IASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALDKKLR 212

Query: 584 MRVARKVSEIVREAGITAVIITHRPE 609
            R+  +V +I+   G+T V++TH  E
Sbjct: 213 DRMQLEVVDILERVGVTCVMVTHDQE 238


>pir||S75960 nitrate transport protein D-1 - Synechocystis sp. (strain PCC 6803)
           >gi|1001320|dbj|BAA10807.1| (D64006) nitrate transport
           protein NrtD [Synechocystis sp.]
           Length = 282
           
 Score = 76.5 bits (185), Expect = 9e-13
 Identities = 62/203 (30%), Positives = 98/203 (47%), Gaps = 38/203 (18%)

Query: 437 VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEV------- 489
           VL N+N T+N GE + V+G SG GK+TLL ++ G           PT G ++V       
Sbjct: 42  VLENVNLTVNEGEFICVIGHSGCGKSTLLNMVSGFAS--------PTDGSVQVGGKIITE 93

Query: 490 PKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNA----------AVEVLNRAGLSDAV 539
           P   ++ V     + P     T LE+VY  +  +++          A + L   GL+D++
Sbjct: 94  PGPDRMVVFQNYALLPWL---TALENVYIAVDAVHSQKTEAEKRAIAKDHLAMVGLTDSM 150

Query: 540 LYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGI 599
               K  ++S G K+R  IA  LA RP VL++DE    LD +T   +  ++ +I  +   
Sbjct: 151 --DKKPGQISGGMKQRVSIARALAIRPEVLILDEPFGALDAITKEELQEELLQIWNDHRC 208

Query: 600 TAVIITHRPEVVKALDPDKVLFV 622
           T ++ITH        D D+ LF+
Sbjct: 209 TVLMITH--------DIDEALFL 223


>sp|Q47538|TAUB_ECOLI TAURINE TRANSPORT ATP-BINDING PROTEIN TAUB >gi|7445736|pir||F64764
           taurine transport protein - Escherichia coli
           >gi|1384059|dbj|BAA12839.1| (D85613) ATP-binding protein
           [Escherichia coli] >gi|1657561|gb|AAB18089.1| (U73857)
           ATP-binding protein [Escherichia coli]
           >gi|1786563|gb|AAC73469.1| (AE000143) taurine
           ATP-binding component of a transport system [Escherichia
           coli K12]
           Length = 255
           
 Score = 76.5 bits (185), Expect = 9e-13
 Identities = 63/205 (30%), Positives = 100/205 (48%), Gaps = 9/205 (4%)

Query: 435 RPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAK 494
           +P L ++N T+  GE++ V+G SG GKTTLL LI G +  Y     +    +IE P   +
Sbjct: 14  KPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVP-YQHGSIQLAGKRIEGPGAER 72

Query: 495 VSV-----LIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLNRAGLSDAVLYRAKFSELS 549
             V     L+P     +  +  +      K++ L  A ++L + GL  A   +    +LS
Sbjct: 73  GVVFQNEGLLPWRNVQDNVAFGLQLAGIEKMQRLEIAHQMLKKVGLEGA--EKRYIWQLS 130

Query: 550 TGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPE 609
            GQ++R  IA  LA  P +LL+DE    LD  T  ++   + ++ +E G   ++ITH  E
Sbjct: 131 GGQRQRVGIARALAANPQLLLLDEPFGALDAFTRDQMQTLLLKLWQETGKQVLLITHDIE 190

Query: 610 VVKALDPDKVLF-VGYGTVIVRKSL 633
               +  + VL   G G V+ R  L
Sbjct: 191 EAVFMATELVLLSSGPGRVLERLPL 215


>emb|CAB56736.1| (AL121600) ABC transport protein, ATP-binding subunit [Streptomyces
           coelicolor A3(2)]
           Length = 252
           
 Score = 76.5 bits (185), Expect = 9e-13
 Identities = 63/201 (31%), Positives = 100/201 (49%), Gaps = 23/201 (11%)

Query: 435 RPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIE------ 488
           RPVLR L   I    V A+VG +G+GK+TLL ++ G I        RPTSG +       
Sbjct: 34  RPVLRQLTCEIPALAVTALVGPNGSGKSTLLGVLAGVI--------RPTSGDLHRDGERP 85

Query: 489 ---VPKNAKVSVLIPGEIEPEFGSETILEH-VYRKI--RDLNAAVEVLNRAGLSDAVLYR 542
              VP+   V+  +P  +          E   +R++  RD       L+R G++D  L  
Sbjct: 86  PAFVPQRGAVADALPLTVRQTVEMGRWAERGPWRRLNRRDRLIVDSALDRLGIAD--LAP 143

Query: 543 AKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAV 602
            +  ELS GQ++RA +A  LA++ ++LL+DE    LD     R+   ++++V + G+T V
Sbjct: 144 RQLGELSGGQRQRALVAQGLAQQSDLLLLDEPTTGLDPEARQRITALLTDLVAD-GVTVV 202

Query: 603 IITHRPEVVKALDPDKVLFVG 623
             TH  E  ++ +   +L  G
Sbjct: 203 HATHDLEAARSAEACLLLRAG 223


>gb|AAF58437.1| (AE003820) Mdr49 gene product [Drosophila melanogaster]
           Length = 1279
           
 Score = 76.5 bits (185), Expect = 9e-13
 Identities = 68/242 (28%), Positives = 114/242 (47%), Gaps = 37/242 (15%)

Query: 410 LDIKG-LPQEIQDLLKAFGVRHRVIQRP---VLRNLNFTINPGEVVAVVGASGAGKTTLL 465
           +D KG  P+     ++  G+R R   RP   +L+ L   + PG+ VA VGASG GK+TL+
Sbjct: 388 MDEKGNRPENTAGHIRFEGIRFRYPARPDVEILKGLTVDVLPGQTVAFVGASGCGKSTLI 447

Query: 466 RLILGAIKGYWEEKYRPTSGKIEVPKN---------AKVSVLIPGEIEPEFGSETILEHV 516
           +L+        +  Y P +G +++             +  + + G+ EP   + TI E++
Sbjct: 448 QLM--------QRFYDPEAGSVKLDGRDLRTLNVGWLRSQIGVVGQ-EPVLFATTIGENI 498

Query: 517 -YRKIRDLNAAVEVLNRAGLSDAVLYRA----------KFSELSTGQKERAKIASLLAER 565
            Y +     A +E   RA      + R           K +++S GQK+R  IA  L  +
Sbjct: 499 RYGRPSATQADIEKAARAANCHDFITRLPKGYDTQVGEKGAQISGGQKQRIAIARALVRQ 558

Query: 566 PNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYG 625
           P VLL+DE  + LD  +  RV   +   +   G T +++ HR   +   + DK++F+  G
Sbjct: 559 PQVLLLDEATSALDPTSEKRVQSALE--LASQGPTTLVVAHRLSTI--TNADKIVFLKDG 614

Query: 626 TV 627
            V
Sbjct: 615 VV 616


 Score = 74.9 bits (181), Expect = 3e-12
 Identities = 74/266 (27%), Positives = 113/266 (41%), Gaps = 56/266 (21%)

Query: 371  FKEDPYAPKEPLWKPSYGKVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRH 430
            FK     P  P  +  Y  VE  EG IV++NV   + +    KG                
Sbjct: 1012 FKRTSTQPNPP--QSPYNTVEKSEGDIVYENVGFEYPTR---KG---------------- 1050

Query: 431  RVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKI--- 487
                 P+L+ LN TI     VA+VG SG+GK+T ++L+L          Y P SG +   
Sbjct: 1051 ----TPILQGLNLTIKKSTTVALVGPSGSGKSTCVQLLL--------RYYDPVSGSVNLS 1098

Query: 488  -----EVPKNAKVSVLIPGEIEPEFGSETILEHV-----YRKIRDLNAAVEVLNRAGLSD 537
                 E P +   S L     EP     TI E++     +R    +   +E   ++ + +
Sbjct: 1099 GVPSTEFPLDTLRSKLGLVSQEPVLFDRTIAENIAYGNNFRDDVSMQEIIEAAKKSNIHN 1158

Query: 538  AV--------LYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARK 589
             +            K S+LS GQK+R  IA  L   P +L++DE  + LD L + +V ++
Sbjct: 1159 FISALPQGYDTRLGKTSQLSGGQKQRIAIARALVRNPKILILDEATSALD-LESEKVVQQ 1217

Query: 590  VSEIVREAGITAVIITHRPEVVKALD 615
              +  R +G T + I HR   V+  D
Sbjct: 1218 ALDEAR-SGRTCLTIAHRLTTVRNAD 1242


>pir||H82377 ABC transporter, ATP-binding protein VCA1101 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9658548|gb|AAF96993.1| (AE004435) ABC transporter,
           ATP-binding protein [Vibrio cholerae]
           Length = 486
           
 Score = 76.5 bits (185), Expect = 9e-13
 Identities = 54/174 (31%), Positives = 91/174 (52%), Gaps = 16/174 (9%)

Query: 440 NLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIE------VPKNA 493
           +L+FT++ GE++ + G SG GK+TL  L+LG +K        P+ G+I       + K  
Sbjct: 307 SLSFTLSAGEILGISGDSGCGKSTLADLLLGLLK--------PSQGRIHRLQAIPLGKAL 358

Query: 494 KVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAV-EVLNRAGLSDAVLYRAKFSELSTGQ 552
           K+    P  +      +T+LE V R+     + +  +L R  LS  +L R K +++S G+
Sbjct: 359 KLYQDPPSALAKSVTLQTLLEDVCRQHSVERSQIPRLLERLALSPNLLSR-KANQVSGGE 417

Query: 553 KERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITH 606
            +R  I   L  RP +L+ DE  + LD +TA    + + E+ +E G   V+I+H
Sbjct: 418 LQRFAILRALLTRPTLLVADEPTSRLDPITAASTLQLIIELTQEIGCALVLISH 471


>pir||G83607 polyamine transport protein PotG PA0302 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9946147|gb|AAG03691.1|AE004468_3 (AE004468)
           polyamine transport protein PotG [Pseudomonas
           aeruginosa]
           Length = 384
           
 Score = 76.5 bits (185), Expect = 9e-13
 Identities = 60/212 (28%), Positives = 106/212 (49%), Gaps = 23/212 (10%)

Query: 412 IKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGA 471
           ++G  Q  + L+K   V  +  +   +  ++ TIN GE+ A++G SG+GK+TLLR++ G 
Sbjct: 12  LEGNQQPKEVLVKIDRVTKQFDETLAVDTVSLTINKGEIFALLGGSGSGKSTLLRMLAGF 71

Query: 472 IKGYWEEKYRPTSGKIEVPKNAKVSVLIPGE--IEPEFGSETILEHV-------YRKIRD 522
                    RPT G+I +     ++ L P E  I   F S  +  H+       +   +D
Sbjct: 72  --------ERPTEGRIFLD-GQDITDLPPYERPINMMFQSYALFPHMSVAQNIAFGLKQD 122

Query: 523 LNAAVEVLNRAGLSDAVLYRAKFS-----ELSTGQKERAKIASLLAERPNVLLIDEFAAH 577
                E+  R      +++  +++     +LS GQ++R  +A  LA+RP +LL+DE    
Sbjct: 123 GLPKAEIDERVAEMLKLVHMTQYAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGA 182

Query: 578 LDTLTAMRVARKVSEIVREAGITAVIITHRPE 609
           LD     ++  ++ EI+   G+T V++TH  E
Sbjct: 183 LDKKLRSQMQLELVEIIERVGVTCVMVTHDQE 214


>dbj|BAB04534.1| (AP001509) ABC transporter (ATP-binding protein) [Bacillus
           halodurans]
           Length = 611
           
 Score = 76.5 bits (185), Expect = 9e-13
 Identities = 62/211 (29%), Positives = 106/211 (49%), Gaps = 17/211 (8%)

Query: 434 QRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLIL-------GAIKGYWEE--KYRPTS 484
           Q+  L NL+F +NPGE VA++G +GAGKTT++RL+        GAI    E+   +   S
Sbjct: 377 QKTTLNNLSFHVNPGETVALIGPTGAGKTTIIRLLSRFYEWDGGAIYVDGEDVTTWDRES 436

Query: 485 GKIEVPKNAKVSVLIPGEIEP--EFGS-ETILEHVYRKIRDLNAAVEVLNRAGLSDAVLY 541
            +  +    + S L  G I     +G  E   E V    +  NA   ++      D VL 
Sbjct: 437 YRRHLAFVLQESFLFQGTIRENIRYGRLEATDEEVEAAAKMANAHSFIMRLPDQYDTVL- 495

Query: 542 RAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITA 601
            +  S +S GQK+   IA  +   P++L++DE  +++DT+T + +   +  ++   G T+
Sbjct: 496 DSDGSGISQGQKQLLSIARAMIANPSILILDEATSNIDTITELNIQEALHRLMN--GRTS 553

Query: 602 VIITHRPEVVKALDPDKVLFVGYGTVIVRKS 632
            +I HR   ++    D +L +  GT++ + S
Sbjct: 554 FVIAHRLNTIQ--HADVILVLEKGTLVEQGS 582


>sp|P45022|YA78_HAEIN PROBABLE AMINO-ACID ABC TRANSPORTER ATP-BINDING PROTEIN HI1078
           >gi|1075335|pir||G64181 ABC-type transport protein
           HI1078 - Haemophilus influenzae
           >gi|1574632|gb|AAC22734.1| (U32788) amino acid ABC
           transporter, ATP-binding protein [Haemophilus influenzae
           Rd]
           Length = 257
           
 Score = 76.1 bits (184), Expect = 1e-12
 Identities = 64/227 (28%), Positives = 113/227 (49%), Gaps = 26/227 (11%)

Query: 422 LLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYR 481
           +LK   ++       VL+ ++F IN GEVVA++G SG+GKTT LR  L  ++   +    
Sbjct: 3   MLKVSNIQKNFNGNHVLKGIDFEINKGEVVAILGPSGSGKTTFLR-CLNLLERPEQGILE 61

Query: 482 PTSGKIEVPKNAKVSVLIPGEIEPE----------FGSETILEHVYR---------KIRD 522
            T G +++  + K+S     ++             F   + LE+V           K + 
Sbjct: 62  FTDGSLKIDFSQKISKADELKLRRRSSMVFQQYNLFPHRSALENVMEGMVVVQKQDKAQA 121

Query: 523 LNAAVEVLNRAGLSD-AVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTL 581
              A+ +L + GL + A L+    S+LS GQ++R  IA  LA +P+++L+DE  + LD  
Sbjct: 122 REKALSLLEKVGLKNKADLFP---SQLSGGQQQRVGIARALAVKPDIILLDEPTSALDPE 178

Query: 582 TAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
               V + +  + +E G T +I+TH  +  K +  D+V+ +  G ++
Sbjct: 179 LVGEVLQTLKMLAQE-GWTMIIVTHEMQFAKDV-ADRVILMADGHIV 223


>pir||E69742 ABC transporter (ATP-binding protein) homolog ybaE - Bacillus
           subtilis >gi|1644203|dbj|BAA10984.1| (D64126) unknown
           [Bacillus subtilis] >gi|2632413|emb|CAB11922.1| (Z99104)
           similar to ABC transporter (ATP-binding protein)
           [Bacillus subtilis]
           Length = 276
           
 Score = 76.1 bits (184), Expect = 1e-12
 Identities = 64/217 (29%), Positives = 103/217 (46%), Gaps = 34/217 (15%)

Query: 434 QRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNA 493
           +R  L ++N +I  G  VAV+G +G+GK+TLL+ + G +K        PT G+I +    
Sbjct: 6   ERLALYDINASIKEGSYVAVIGHTGSGKSTLLQHLNGLLK--------PTKGQISLGSTV 57

Query: 494 ---------------KVSVLIPGEIEPEFGSETILEHV--------YRKIRDLNAAVEVL 530
                          KV ++     E +   ET+L+ +         +K      A E+L
Sbjct: 58  IQAGKKNKDLKKLRKKVGIVFQFP-EHQLFEETVLKDISFGPMNFGVKKEDAEQKAREML 116

Query: 531 NRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKV 590
              GLS+ +L R+ F ELS GQ  R  IA +LA  P VL++DE  A LD      +    
Sbjct: 117 QLVGLSEELLDRSPF-ELSGGQMRRVAIAGVLAMDPEVLVLDEPTAGLDPRGRKEIMDMF 175

Query: 591 SEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTV 627
            E+ +   +T +++TH  E   A   D+++ +  GT+
Sbjct: 176 YELHQRGNLTTILVTHSMEDAAAY-ADEMIVMHKGTI 211


>pir||S77459 ABC-type transport protein slr1149 - Synechocystis sp.  (strain PCC
           6803) >gi|1652384|dbj|BAA17306.1| (D90905) ABC
           transporter [Synechocystis sp.]
           Length = 601
           
 Score = 76.1 bits (184), Expect = 1e-12
 Identities = 69/256 (26%), Positives = 121/256 (46%), Gaps = 31/256 (12%)

Query: 391 EMLEGPIVFKNVTKVFESELD--IKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPG 448
           E++E P+  K+   +   E++  ++G   EI      FG +       VL+NLNFTI PG
Sbjct: 333 ELMEEPVEIKDQAVITPIEINGALRGSHGEICFENVWFGYKP---DEYVLKNLNFTIKPG 389

Query: 449 EVVAVVGASGAGKTTLLRLILGA--------------IKGYWEEKYRPTSGKIEVPKNAK 494
           E VA+VG +GAGK++++RL+                 I+   +++ R   G I      +
Sbjct: 390 EKVALVGPTGAGKSSIIRLLCRLHDPSRGRILVDGIDIRELSQQQLRRFIGVI-----LQ 444

Query: 495 VSVLIPGEIEPE--FGSETILEHVYRKIRDLNAAVEVLNRAGLSDAVLYRAKFSELSTGQ 552
            S L  G+++     G E  LE V R  + L +   ++           R + S LS GQ
Sbjct: 445 DSFLFAGDVKRNITLGEEYSLEEVQRAAQ-LTSVDRLIEELPQGYHTQLRERGSNLSGGQ 503

Query: 553 KERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVK 612
           K+    A +    P VL++DE  A LD  T   +   +  ++++   T++II HR   ++
Sbjct: 504 KQLLAFARVAIREPYVLVMDEATASLDVRTEADIQAALLHLLQDR--TSIIIAHRLSTIR 561

Query: 613 ALDPDKVLFVGYGTVI 628
             + D++  + +G ++
Sbjct: 562 --NVDRIFVLKHGEIV 575


>gb|AAB58722.2| (AF001155) TAP2 [Mesocricetus auratus]
           Length = 729
           
 Score = 76.1 bits (184), Expect = 1e-12
 Identities = 66/236 (27%), Positives = 116/236 (48%), Gaps = 38/236 (16%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E QD+  ++  R    ++PVL+ L FT++PG+V A+VG +G+GK+T+  L+        +
Sbjct: 494 EFQDVTFSYPSRP---EKPVLKGLTFTLHPGKVTALVGPNGSGKSTVAALL--------Q 542

Query: 478 EKYRPTSGKIEVPKNAKV---------SVLIPGEIEPEFGSETILEHVYRKIRDL-NAAV 527
             Y+PT G++ +     V          V++ G+ EP   S ++ +++   ++D  +A V
Sbjct: 543 NLYQPTGGQLLLDGQPLVQYDHHYLHRQVVLVGQ-EPVLFSGSVKDNIAYGLKDCEDAQV 601

Query: 528 EVLNRAGLSDAVL----------YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAH 577
               RA  +D  +             K S+L+ GQK+R  IA  L   P VL++DE  + 
Sbjct: 602 MAAVRAACADDFIGEMPDGIHTEIGEKGSQLAVGQKQRLAIARALVRNPRVLILDEATSA 661

Query: 578 LDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
           LD+     +    S+  R    T ++I HR   V+  + D+VL +  G ++    L
Sbjct: 662 LDSQCEQALQAWRSKGDR----TVLVIAHRLHTVQ--NVDQVLVLKQGQLVEHSQL 711


>gb|AAB58724.2| (AF001157) TAP2 [Mesocricetus auratus]
           Length = 729
           
 Score = 76.1 bits (184), Expect = 1e-12
 Identities = 66/236 (27%), Positives = 116/236 (48%), Gaps = 38/236 (16%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E QD+  ++  R    ++PVL+ L FT++PG+V A+VG +G+GK+T+  L+        +
Sbjct: 494 EFQDVTFSYPSRP---EKPVLKGLTFTLHPGKVTALVGPNGSGKSTVAALL--------Q 542

Query: 478 EKYRPTSGKIEVPKNAKV---------SVLIPGEIEPEFGSETILEHVYRKIRDL-NAAV 527
             Y+PT G++ +     V          V++ G+ EP   S ++ +++   ++D  +A V
Sbjct: 543 NLYQPTGGQLLLDGQPLVQYDHHYLHRQVVLVGQ-EPVLFSGSVKDNIAYGLKDCEDAQV 601

Query: 528 EVLNRAGLSDAVL----------YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAH 577
               RA  +D  +             K S+L+ GQK+R  IA  L   P VL++DE  + 
Sbjct: 602 MAAVRAACADDFIGEMPDGIHTEIGEKGSQLAVGQKQRLAIARALVRNPRVLILDEATSA 661

Query: 578 LDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
           LD+     +    S+  R    T ++I HR   V+  + D+VL +  G ++    L
Sbjct: 662 LDSQCEQALQAWRSKGDR----TVLVIAHRLHTVQ--NVDQVLVLKQGQLVEHSQL 711


>dbj|BAB04930.1| (AP001511) ABC transporter (ATP-binding protein) [Bacillus
           halodurans]
           Length = 264
           
 Score = 76.1 bits (184), Expect = 1e-12
 Identities = 66/217 (30%), Positives = 102/217 (46%), Gaps = 24/217 (11%)

Query: 419 IQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEE 478
           I+D+ K F  +       V  N+N  I+ GE V+++G SG GK+TLL ++ G  K     
Sbjct: 6   IKDVGKTFEGKEEQSSYQVFENINLEIHSGEFVSLLGPSGCGKSTLLNIVAGLEKA---- 61

Query: 479 KYRPTSGKIEVPKNAKVSVLIPGEIEPEFGSE-------TILEHVYRKIRDLNAAVEVLN 531
               ++G + V +N    V+ PG        E       T+L++V   IR      E   
Sbjct: 62  ----SNGAVYVGQN---KVIEPGPDRGVVFQEAALMPWLTVLDNVVFAIRKQYNKEEAKK 114

Query: 532 RAGLSDAVLYRAKFS-----ELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRV 586
           RA     +++ +KF+     ELS G K+R  IA  LA  P+VLL+DE    LD  T   +
Sbjct: 115 RALEYLKLVHLSKFTHSYPHELSGGMKQRVAIARALALDPDVLLMDEPFGALDEQTRSML 174

Query: 587 ARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVG 623
            R++  I ++   T + +TH       L  DK+  +G
Sbjct: 175 HRELQAIWQQTKKTIIFVTHNIREAILLS-DKIFLMG 210


>gb|AAG25076.1|AF273216_1 (AF273216) ABC transporter RzcB [Rhizobium leguminosarum bv.
           viciae]
           Length = 735
           
 Score = 76.1 bits (184), Expect = 1e-12
 Identities = 63/210 (30%), Positives = 103/210 (49%), Gaps = 32/210 (15%)

Query: 424 KAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPT 483
           K+   R+    + VL+++NF+I PGEV+ +VG SG+GK+TL +L+        +  Y P 
Sbjct: 494 KSVNFRYSPDGQDVLKDINFSIRPGEVIGIVGPSGSGKSTLTKLV--------QRFYIPN 545

Query: 484 SGKIEVPKNAKVSVLIPGEIEPEFG---SETIL---EHVYRKIRDLNAAVE---VLNRAG 534
           +G++ V     ++ + P  +    G    E +L     ++  I  +N A+     +  A 
Sbjct: 546 NGQVFV-DGQDIAQVDPAWLRSNIGVVLQENMLLFNRTIHDNICMVNPAMSRAAAIQMAR 604

Query: 535 LSDAVLYRAKF------------SELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLT 582
           LS A  + AK             + LS GQ++R  IA  LA  P +L++DE  + LD  +
Sbjct: 605 LSGADQFIAKLPRGYDTLIEERGANLSGGQRQRLAIARALATNPPILILDEATSALDYES 664

Query: 583 AMRVARKVSEIVREAGITAVIITHRPEVVK 612
              +   + EIVR  G T +II HR   V+
Sbjct: 665 ERIILGNMREIVR--GRTVIIIAHRLATVR 692


>gi|6323217 ATP-binding cassette (ABC) transporter family member; Mdl1p
           [Saccharomyces cerevisiae]
           >gi|1346512|sp|P33310|MDL1_YEAST ATP-DEPENDENT PERMEASE
           MDL1 >gi|1078101|pir||S51433 MDL1 protein - yeast
           (Saccharomyces cerevisiae) >gi|577195|gb|AAB67455.1|
           (U17246) Mdl1p [Saccharomyces cerevisiae]
           Length = 695
           
 Score = 75.7 bits (183), Expect = 1e-12
 Identities = 77/271 (28%), Positives = 124/271 (45%), Gaps = 51/271 (18%)

Query: 379 KEPLWKPSYGK--VEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRP 436
           ++PL +P+ GK  V + + PIVFKNV+  + +                    +H++    
Sbjct: 412 RKPLIRPTIGKDPVSLAQKPIVFKNVSFTYPTR------------------PKHQIF--- 450

Query: 437 VLRNLNFTINPGEVVAVVGASGAGKTTLLRLIL--------------GAIKGYWEEKYRP 482
             ++LN TI PGE V  VG SG+GK+T+  L+L                I+ +   KYR 
Sbjct: 451 --KDLNITIKPGEHVCAVGPSGSGKSTIASLLLRYYDVNSGSIEFGDEDIRNFNLRKYRR 508

Query: 483 TSGKIEVPK---NAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLN-RAGLSDA 538
             G ++      N  +   I   I PE   +   + + R I   N    + N   GL   
Sbjct: 509 LIGYVQQEPLLFNGTILDNILYCIPPEIAEQD--DRIRRAIGKANCTKFLANFPDGLQTM 566

Query: 539 VLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAG 598
           V   A+ ++LS GQK+R  +A      P VL++DE  + LD+ +   VA+ +   V E G
Sbjct: 567 V--GARGAQLSGGQKQRIALARAFLLDPAVLILDEATSALDSQSEEIVAKNLQRRV-ERG 623

Query: 599 ITAVIITHRPEVVKALDPDKVLFVG-YGTVI 628
            T + I HR   +K     +V+ +G +G+V+
Sbjct: 624 FTTISIAHRLSTIK--HSTRVIVLGKHGSVV 652


>dbj|BAA12015.1| (D83582) metalloprotease transporter [Serratia marcescens]
           Length = 582
           
 Score = 75.7 bits (183), Expect = 1e-12
 Identities = 60/207 (28%), Positives = 101/207 (47%), Gaps = 29/207 (14%)

Query: 436 PVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKV 495
           PVL  ++F +  GEV+ V+GASG+GKT L+R ++GA+         P SG + +   A +
Sbjct: 335 PVLHGVSFRLEAGEVLGVIGASGSGKTLLMRQLVGAL--------TPLSGDVRL-DGADI 385

Query: 496 SVLIPGEIEPEFG---------SETILEHVYRKIR-DLNAAVEVLNRAGLSDAVLYRAKF 545
                 ++ P +G         + T+ E++ R  + D    V     AG+   +L+  K 
Sbjct: 386 RQWDKQQLGPLYGYLPQDIQLFAGTLTENIARFGQVDAEKVVAAAALAGVHQLILHLPKG 445

Query: 546 SE---------LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVRE 596
            E         LS GQ++R  +A  L   P ++++DE  A+LD      + R + E ++ 
Sbjct: 446 YETELGEGGSGLSGGQRQRVALARALYGSPALVVLDEPNANLDREGEEALLRAI-EALKA 504

Query: 597 AGITAVIITHRPEVVKALDPDKVLFVG 623
            G T V++TH+P ++   D   VL  G
Sbjct: 505 RGTTIVLVTHKPAILATTDKLLVLAAG 531


>pir||T42842 bile salt transport protein, ATP-dependent - rat
           >gi|3075422|gb|AAC40084.1| (U69487) bile salt export
           pump [Rattus norvegicus]
           Length = 1321
           
 Score = 75.7 bits (183), Expect = 1e-12
 Identities = 69/247 (27%), Positives = 109/247 (43%), Gaps = 54/247 (21%)

Query: 389 KVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPG 448
           K++ ++G I F NVT  + S  D+K                       +L NL+  I PG
Sbjct: 412 KLDRIKGEIEFHNVTFHYPSRPDVK-----------------------ILDNLSMVIKPG 448

Query: 449 EVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVSVLIP------GE 502
           E  A+VG+SGAGK+T L+LI        +  Y P  G + +  +   S+ I       G 
Sbjct: 449 ETTALVGSSGAGKSTALQLI--------QRFYDPCEGMVTLDGHDIRSLNIRWLRDQIGI 500

Query: 503 IEPE-------------FGSE-TILEHVYRKIRDLNAAVEVLNRAGLSDAVLYRAKFSEL 548
           +E E             FG E   +E + +  +D NA   ++      D ++      ++
Sbjct: 501 VEQEPVLFSTTIAENIRFGREDATMEDIVQAAKDANAYNFIMALPQQFDTLVGEGG-GQM 559

Query: 549 STGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRP 608
           S GQK+R  IA  L   P +LL+D   + LD  +  RV   +++I  + G T + + HR 
Sbjct: 560 SGGQKQRVAIARALIRNPKILLLDMATSALDNESEARVQEALNKI--QHGHTIISVAHRL 617

Query: 609 EVVKALD 615
             V+A D
Sbjct: 618 STVRAAD 624


 Score = 71.0 bits (171), Expect = 4e-11
 Identities = 82/322 (25%), Positives = 137/322 (42%), Gaps = 65/322 (20%)

Query: 337  FEKVGFKFVWE---------TASGRPVLIYPLTQEAKEYLERYFKEDPYAPKEPLWKPSY 387
            +E +GF  V+          TA GR     P   +AK    R+F+     P   ++  + 
Sbjct: 1009 YEGLGFSHVFRVVSSVALSATAVGRTFSYTPSYAKAKISAARFFQLLDRKPPINVYSEAG 1068

Query: 388  GKVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINP 447
             K +  +G I F +    + S  DI+                       VL  L+ ++NP
Sbjct: 1069 EKWDNFQGKIDFIDCKFTYPSRPDIQ-----------------------VLNGLSVSVNP 1105

Query: 448  GEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVP--KNAKVSV-LIPGEI- 503
            G+ +A VG+SG GK+T ++L+        E  Y P  G + +    + KV++  +   I 
Sbjct: 1106 GQTLAFVGSSGCGKSTSIQLL--------ERFYDPDQGTVMIDGHDSKKVNIQFLRSNIG 1157

Query: 504  ----EPEFGSETILEHV----YRKIRDLNAAVEVLNRAGLSDAVL-----YRAKF----S 546
                EP     +I++++      K   +  A+    +A L D V+     Y        S
Sbjct: 1158 IVSQEPVLFDCSIMDNIKYGDNTKEISVERAIAAAKQAQLHDFVMSLPEKYETNVGIQGS 1217

Query: 547  ELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITH 606
            +LS G+K+R  IA  +   P +LL+DE  + LDT +   V   + +  RE G T ++I H
Sbjct: 1218 QLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQTALDK-ARE-GRTCIVIAH 1275

Query: 607  RPEVVKALDPDKVLFVGYGTVI 628
            R   ++  + D +  V  G VI
Sbjct: 1276 RLSTIQ--NSDIIAVVSQGVVI 1295


>pir||T42228 P-glycoprotein sister - rat >gi|3273484|gb|AAC24753.1| (AF010597)
           P-glycoprotein sister [Rattus norvegicus]
           Length = 1321
           
 Score = 75.7 bits (183), Expect = 1e-12
 Identities = 69/247 (27%), Positives = 109/247 (43%), Gaps = 54/247 (21%)

Query: 389 KVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPG 448
           K++ ++G I F NVT  + S  D+K                       +L NL+  I PG
Sbjct: 412 KLDRIKGEIEFHNVTFHYPSRPDVK-----------------------ILDNLSMVIKPG 448

Query: 449 EVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVSVLIP------GE 502
           E  A+VG+SGAGK+T L+LI        +  Y P  G + +  +   S+ I       G 
Sbjct: 449 ETTALVGSSGAGKSTALQLI--------QRFYDPCEGMVTLDGHDIRSLNIRWLRDQIGI 500

Query: 503 IEPE-------------FGSE-TILEHVYRKIRDLNAAVEVLNRAGLSDAVLYRAKFSEL 548
           +E E             FG E   +E + +  +D NA   ++      D ++      ++
Sbjct: 501 VEQEPVLFSTTIAENIRFGREDATMEDIVQAAKDANAYNFIMALPQQFDTLVGEGG-GQM 559

Query: 549 STGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRP 608
           S GQK+R  IA  L   P +LL+D   + LD  +  RV   +++I  + G T + + HR 
Sbjct: 560 SGGQKQRVAIARALIRNPKILLLDMATSALDNESEARVQEALNKI--QHGHTIISVAHRL 617

Query: 609 EVVKALD 615
             V+A D
Sbjct: 618 STVRAAD 624


 Score = 71.0 bits (171), Expect = 4e-11
 Identities = 82/322 (25%), Positives = 137/322 (42%), Gaps = 65/322 (20%)

Query: 337  FEKVGFKFVWE---------TASGRPVLIYPLTQEAKEYLERYFKEDPYAPKEPLWKPSY 387
            +E +GF  V+          TA GR     P   +AK    R+F+     P   ++  + 
Sbjct: 1009 YEGLGFSHVFRVVSSVVLSATAVGRTFSYTPSYAKAKISAARFFQLLDRKPPINVYSEAG 1068

Query: 388  GKVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINP 447
             K +  +G I F +    + S  DI+                       VL  L+ ++NP
Sbjct: 1069 EKWDNFQGKIDFIDCKFTYPSRPDIQ-----------------------VLNGLSVSVNP 1105

Query: 448  GEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVP--KNAKVSV-LIPGEI- 503
            G+ +A VG+SG GK+T ++L+        E  Y P  G + +    + KV++  +   I 
Sbjct: 1106 GQTLAFVGSSGCGKSTSIQLL--------ERFYDPDQGTVMIDGHDSKKVNIQFLRSNIG 1157

Query: 504  ----EPEFGSETILEHV----YRKIRDLNAAVEVLNRAGLSDAVL-----YRAKF----S 546
                EP     +I++++      K   +  A+    +A L D V+     Y        S
Sbjct: 1158 IVSQEPVLFDCSIMDNIKYGDNTKEISVERAIAAAKQAQLHDFVMSLPEKYETNVGIQGS 1217

Query: 547  ELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITH 606
            +LS G+K+R  IA  +   P +LL+DE  + LDT +   V   + +  RE G T ++I H
Sbjct: 1218 QLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQTALDK-ARE-GRTCIVIAH 1275

Query: 607  RPEVVKALDPDKVLFVGYGTVI 628
            R   ++  + D +  V  G VI
Sbjct: 1276 RLSTIQ--NSDIIAVVSQGVVI 1295


>gi|4502457 ATP-binding cassette, sub-family B (MDR/TAP), member 11; ABC member
           16, MDR/TAP subfamily; bile salt export pump;
           progressive familial intrahepatic cholestasis 2 [Homo
           sapiens] >gi|3873243|gb|AAC77455.1| (AF091582) bile salt
           export pump [Homo sapiens]
           Length = 1321
           
 Score = 75.7 bits (183), Expect = 1e-12
 Identities = 71/262 (27%), Positives = 115/262 (43%), Gaps = 56/262 (21%)

Query: 389 KVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPG 448
           K++ ++G I F NVT  + S  ++K                       +L +LN  I PG
Sbjct: 412 KLDRIKGEIEFHNVTFHYPSRPEVK-----------------------ILNDLNMVIKPG 448

Query: 449 EVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVSVLIPG------- 501
           E+ A+VG SGAGK+T L+LI        +  Y P  G + V  +   S+ I         
Sbjct: 449 EMTALVGPSGAGKSTALQLI--------QRFYDPCEGMVTVDGHDIRSLNIQWLRDQIGI 500

Query: 502 -EIEPEFGSETI------------LEHVYRKIRDLNAAVEVLNRAGLSDAVLYRAKFSEL 548
            E EP   S TI            +E + +  ++ NA   +++     D ++      ++
Sbjct: 501 VEQEPVLFSTTIAENIRYGREDATMEDIVQAAKEANAYNFIMDLPQQFDTLVGEGG-GQM 559

Query: 549 STGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRP 608
           S GQK+R  IA  L   P +LL+D   + LD  +   V   +S+I  + G T + + HR 
Sbjct: 560 SGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEVLSKI--QHGHTIISVAHRL 617

Query: 609 EVVKALDPDKVLFVGYGTVIVR 630
             V+A   D ++   +GT + R
Sbjct: 618 STVRA--ADTIIGFEHGTAVER 637


>pir||T31073 multidrug resistance p-glycoprotein - nematode (Haemonchus contortus)
            >gi|3057042|gb|AAC38987.1| (AF003908) P-glycoprotein
            [Haemonchus contortus]
            Length = 1275
            
 Score = 75.7 bits (183), Expect = 1e-12
 Identities = 66/211 (31%), Positives = 100/211 (47%), Gaps = 35/211 (16%)

Query: 437  VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVP------ 490
            VLR LN  INPG  VA+VG SG GK+T++ L+        E  Y    G I V       
Sbjct: 1047 VLRGLNLEINPGTTVALVGQSGCGKSTVMALL--------ERFYNQNKGVITVDGENIRN 1098

Query: 491  ---KNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLNRA-----------GLS 536
               +N +  V I  + EP     TI+E++   + D   + E +  A           GL 
Sbjct: 1099 MNIRNLREQVCIVSQ-EPTLFDCTIMENICYGLDDPKPSYEQVVAAAKMANIHNFVLGLP 1157

Query: 537  DAVLYRA--KFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIV 594
            +    R   K ++LS GQK+R  IA  L   P +LL+DE  + LDT  + ++ +   E+ 
Sbjct: 1158 EGYDTRVGEKGTQLSGGQKQRIAIARALIRDPPILLLDEATSALDT-ESEKIVQDALEVA 1216

Query: 595  REAGITAVIITHRPEVVKALDPDKVLFVGYG 625
            R+ G T ++I HR   ++  D D ++ +  G
Sbjct: 1217 RQ-GRTCLVIAHRLSTIQ--DSDVIVMIQEG 1244


>pir||B72097 dipeptide transporter ATPase - Chlamydophila pneumoniae  (strain
           CWL029) >gi|4376554|gb|AAD18429.1| (AE001613) Dipeptide
           Transporter ATPase [Chlamydophila pneumoniae CWL029]
           >gi|8163441|gb|AAF73675.1| (AE002208) ABC transporter,
           ATP-binding protein [Chlamydophila pneumoniae AR39]
           >gi|8978654|dbj|BAA98490.1| (AP002546) dipeptide
           transporter ATPase [Chlamydophila pneumoniae J138]
           Length = 341
           
 Score = 75.7 bits (183), Expect = 1e-12
 Identities = 59/220 (26%), Positives = 103/220 (46%), Gaps = 41/220 (18%)

Query: 419 IQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEE 478
           +QD+ K  G         +L  ++F++ PGEV  +VG SG+GKTTLLR +        + 
Sbjct: 11  VQDVSKKLG------DHILLSKVSFSVYPGEVFGIVGHSGSGKTTLLRCL--------DF 56

Query: 479 KYRPTSGKIEVP-------------KNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNA 525
              PTSG I V              +N    V    +    F S+T+ E++   +R  ++
Sbjct: 57  LDMPTSGSISVAGFDNSLPTQKFSRRNFSKKVAYISQNYGLFSSKTVFENIAYPLRIHHS 116

Query: 526 AVEVLNRAGLSDAVLYRAKF-----------SELSTGQKERAKIASLLAERPNVLLIDEF 574
               ++++ + + V     F             LS GQK++  IA  +  +P V+L DE 
Sbjct: 117 E---MSKSEVEEQVYDTLNFLNLYHRHDAYPGNLSGGQKQKVAIARAIVCQPEVVLCDEI 173

Query: 575 AAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKAL 614
            + LD  +   +  ++ ++ +E GIT V+++H  +VVK +
Sbjct: 174 TSALDPKSTENIIERLLQLNQERGITLVLVSHEIDVVKKI 213


>gb|AAD28285.1|AF136523_1 (AF136523) bile salt export pump [Homo sapiens]
           Length = 1321
           
 Score = 75.7 bits (183), Expect = 1e-12
 Identities = 71/262 (27%), Positives = 115/262 (43%), Gaps = 56/262 (21%)

Query: 389 KVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPG 448
           K++ ++G I F NVT  + S  ++K                       +L +LN  I PG
Sbjct: 412 KLDRIKGEIEFHNVTFHYPSRPEVK-----------------------ILNDLNMAIKPG 448

Query: 449 EVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVSVLIPG------- 501
           E+ A+VG SGAGK+T L+LI        +  Y P  G + V  +   S+ I         
Sbjct: 449 EMTALVGPSGAGKSTALQLI--------QRFYDPCEGMVTVDGHDIRSLNIQWLRDQIGI 500

Query: 502 -EIEPEFGSETI------------LEHVYRKIRDLNAAVEVLNRAGLSDAVLYRAKFSEL 548
            E EP   S TI            +E + +  ++ NA   +++     D ++      ++
Sbjct: 501 VEQEPVLFSTTIAENIRYGREDATMEDIVQAAKEANAYNFIMDLPQQFDTLVGEGG-GQM 559

Query: 549 STGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRP 608
           S GQK+R  IA  L   P +LL+D   + LD  +   V   +S+I  + G T + + HR 
Sbjct: 560 SGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEVLSKI--QHGHTIISVAHRL 617

Query: 609 EVVKALDPDKVLFVGYGTVIVR 630
             V+A   D ++   +GT + R
Sbjct: 618 STVRA--ADTIIGFEHGTAVER 637


>emb|CAB88985.1| (AL353864) putative ABC-transport protein. [Streptomyces coelicolor
           A3(2)]
           Length = 624
           
 Score = 75.7 bits (183), Expect = 1e-12
 Identities = 63/212 (29%), Positives = 97/212 (45%), Gaps = 33/212 (15%)

Query: 437 VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVS 496
           VL  L+F   PG+ +A+VG+SGAGK+T+ +L+           Y    G + V     V 
Sbjct: 394 VLHGLSFRAEPGQTIALVGSSGAGKSTIAQLL--------PRLYDTDGGTVRV-GGVDVR 444

Query: 497 VLIPGEIEPEFGSETILEHVYRKIRDLNAAV-----------EVLNRAGLSDAV------ 539
            L    +    G  T   H++      N  +           E L RA L+D V      
Sbjct: 445 ELSARSLRDTVGMVTQDGHLFHDTVRANLLLARPDATEDDLWEALRRARLADLVRSLPDG 504

Query: 540 ---LYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVRE 596
              +   +   LS G+++R  IA LL  R  V+++DE  AHLD  +   V   ++E ++ 
Sbjct: 505 LDTVVGERGYRLSGGERQRMTIARLLLARQRVVILDEATAHLDNTSEAAVQEALTEALQ- 563

Query: 597 AGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
            G TAV+I HR   V+A   D++L V  G ++
Sbjct: 564 -GRTAVVIAHRLSTVRA--ADRILVVEAGRIV 592


>pir||H82440 ABC transporter, ATP-binding protein VCA0602 [imported] - Vibrio
           cholerae (group O1 strain N16961)
           >gi|9658013|gb|AAF96503.1| (AE004390) ABC transporter,
           ATP-binding protein [Vibrio cholerae]
           Length = 403
           
 Score = 75.7 bits (183), Expect = 1e-12
 Identities = 64/229 (27%), Positives = 112/229 (47%), Gaps = 40/229 (17%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           +I+ ++K FG          L+ ++ +I  GE V  +G SG GKTTLLR I G       
Sbjct: 36  DIRHVVKQFG------SFTALKEISLSIEKGEFVCFLGPSGCGKTTLLRAIAGLDL---- 85

Query: 478 EKYRPTSGKIEVPKNAKVSVLIPGEIEPEFG----------SETILEHVYRKIRDLNAAV 527
               PTSG I   +N +    +P E + +FG          + T+ E++   +R+   +V
Sbjct: 86  ----PTSGTIH--QNQQAITFLPPE-QRDFGIVFQSYALFPNLTVEENIAIGLRNQGMSV 138

Query: 528 --------EVLNRAGLSDAVLYRAKF-SELSTGQKERAKIASLLAERPNVLLIDEFAAHL 578
                   + L   GL+ +     K+ S+LS GQ++R  +A  LA  P +LL+DE  + L
Sbjct: 139 RDALEKVEQWLEMIGLATSA---QKYPSQLSGGQQQRVALARALALSPGLLLLDEPLSAL 195

Query: 579 DTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTV 627
           D      +  ++ ++ R+ GIT +++TH  E    +  D+++ + +G +
Sbjct: 196 DAKVRTHLREEICQLQRKLGITTIMVTHDQEEALTM-ADRIVVMNHGVI 243


>pir||C83221 transport protein HasD PA3406 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9949543|gb|AAG06794.1|AE004761_10
           (AE004761) transport protein HasD [Pseudomonas
           aeruginosa]
           Length = 600
           
 Score = 75.7 bits (183), Expect = 1e-12
 Identities = 58/201 (28%), Positives = 99/201 (48%), Gaps = 29/201 (14%)

Query: 434 QRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNA 493
           ++ +L++L F + PGE + V+G SG+GK+TL RL++GA        ++P SG + +   A
Sbjct: 345 EQALLQDLGFALEPGEALGVIGPSGSGKSTLARLLVGA--------WQPLSGAVRL-DGA 395

Query: 494 KVSVLIPGEIEPEFG---------SETILEHVYRKIR-DLNAAVEVLNRAGLSDAVL--- 540
            +       + P  G         + +I E++ R    D    V     AG+ D VL   
Sbjct: 396 DLRQWSAAALGPHIGYLAQDVQLFAGSIAENIARFAEVDAEKVVAAARLAGVHDLVLRLP 455

Query: 541 --YRAKFSE----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIV 594
             Y  +  +    LS GQ++R  +A  L  RP ++++DE  A LD      +A  ++  +
Sbjct: 456 QGYDTRLGDGGAGLSGGQRQRIGLARALYGRPALIVLDEPNASLDEAGEAALAEAIA-AM 514

Query: 595 REAGITAVIITHRPEVVKALD 615
           R  G + V++TH+P V+   D
Sbjct: 515 RRQGSSLVLVTHKPAVLALTD 535


>gi|11430459 ATP-binding cassette, sub-family B (MDR/TAP), member 11 [Homo
           sapiens]
           Length = 1321
           
 Score = 75.7 bits (183), Expect = 1e-12
 Identities = 71/262 (27%), Positives = 115/262 (43%), Gaps = 56/262 (21%)

Query: 389 KVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPG 448
           K++ ++G I F NVT  + S  ++K                       +L +LN  I PG
Sbjct: 412 KLDRIKGEIEFHNVTFHYPSRPEVK-----------------------ILNDLNMVIKPG 448

Query: 449 EVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVSVLIPG------- 501
           E+ A+VG SGAGK+T L+LI        +  Y P  G + V  +   S+ I         
Sbjct: 449 EMTALVGPSGAGKSTALQLI--------QRFYDPCEGMVTVDGHDIRSLNIQWLRDQIGI 500

Query: 502 -EIEPEFGSETI------------LEHVYRKIRDLNAAVEVLNRAGLSDAVLYRAKFSEL 548
            E EP   S TI            +E + +  ++ NA   +++     D ++      ++
Sbjct: 501 VEQEPVLFSTTIAENIRYGREDATMEDIVQAAKEANAYNFIMDLPQQFDTLVGEGG-GQM 559

Query: 549 STGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRP 608
           S GQK+R  IA  L   P +LL+D   + LD  +   V   +S+I  + G T + + HR 
Sbjct: 560 SGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEVLSKI--QHGHTIISVAHRL 617

Query: 609 EVVKALDPDKVLFVGYGTVIVR 630
             V+A   D ++   +GT + R
Sbjct: 618 STVRA--ADTIIGFEHGTAVER 637


>pir||E82879 ABC transporter UU539 [imported] - Ureaplasma urealyticum
           >gi|6899543|gb|AAF30952.1|AE002152_11 (AE002152) ABC
           transporter [Ureaplasma urealyticum]
           Length = 294
           
 Score = 75.7 bits (183), Expect = 1e-12
 Identities = 67/220 (30%), Positives = 105/220 (47%), Gaps = 46/220 (20%)

Query: 434 QRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEV---- 489
           +R +L+N++FTIN  E V V+G +G+GK+T+ +++ G +K        P SG I++    
Sbjct: 39  ERMILKNVSFTINDNEYVCVIGHNGSGKSTISKVLTGLLK--------PKSGVIKLFGIE 90

Query: 490 -------------------PKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVL 530
                              P N  V +    +I   FG E       RK+   N   +++
Sbjct: 91  ISAANLKYLRNNIGIVFQNPDNQFVGITAEDDI--AFGLEN------RKVPP-NKMWDII 141

Query: 531 NRAGLSDAV--LYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVAR 588
           N A ++  +  L + +  ELS GQK+R  IAS+LA  P V++ DE  + LD      +  
Sbjct: 142 NDAAVATGIEDLLKKESLELSGGQKQRVAIASVLAINPKVIIFDESTSMLDPKGKNELKE 201

Query: 589 KVSEIVREAGITAVIITH-RPEVVKALDPDKVLFVGYGTV 627
            +  +   A  T + ITH   EVVKA   DKV+ +  G V
Sbjct: 202 LMVSLRDVAKKTIISITHDMEEVVKA---DKVIVMSNGEV 238


>gb|AAK42548.1| ABC transporter, ATP binding protein [Sulfolobus solfataricus]
           Length = 248
           
 Score = 75.3 bits (182), Expect = 2e-12
 Identities = 59/221 (26%), Positives = 104/221 (46%), Gaps = 16/221 (7%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E Q  +    +R R+  + +L+ L+F +  GEV  +VG +GAGKTT LR++ G IK +  
Sbjct: 5   EKQFAVSVTNLRKRIGNKEILKGLSFDVESGEVFGIVGPNGAGKTTTLRILAGIIKNFNG 64

Query: 478 EKYRPTSGKIEVPKNAKVSVL----IPGEIEPEFGSETILEHVYR------KIRDLNAAV 527
           +        IE  +N  +S +     P E    + +      +Y       K + L   +
Sbjct: 65  DAKVFGLRPIEAKQNGYISYMPEDAFPYEKLTGYENLDFYAELYAKGDKELKEKYLKLGI 124

Query: 528 EVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVA 587
           E+ N   L + +    K +E S G K R  IA  L   P + ++DE  + LD  +A+R+ 
Sbjct: 125 EIAN---LGERIY--DKTAEYSRGMKRRLIIARTLMVMPKLSVLDEPTSALDVESAVRIR 179

Query: 588 RKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
             + E+ R   +T ++ +H    V+ L  D++  +  G ++
Sbjct: 180 NIILEMARRYNMTIILSSHNMLEVEYL-CDRITLINDGRIV 219


>sp|P23174|MDR3_CRIGR MULTIDRUG RESISTANCE PROTEIN 3 (P-GLYCOPROTEIN 3)
           >gi|2119778|pir||I48123 p-glycoprotein isoform III -
           Chinese hamster >gi|191169|gb|AAA68885.1| (M60042)
           p-glycoprotein isoform III [Cricetulus griseus]
           Length = 1281
           
 Score = 75.3 bits (182), Expect = 2e-12
 Identities = 63/199 (31%), Positives = 95/199 (47%), Gaps = 31/199 (15%)

Query: 437 VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVP----KN 492
           +L+ LN  +  G+ VA+VG SG GKTT L+L+        +  Y PT G I +     +N
Sbjct: 411 ILKGLNLKVQSGQTVALVGNSGCGKTTTLQLL--------QRLYDPTEGTISIDGQDIRN 462

Query: 493 AKVSVL--IPGEI--EPEFGSETI------------LEHVYRKIRDLNAAVEVLNRAGLS 536
             V  L  I G +  EP   S TI            +E + + +++ N A E + +    
Sbjct: 463 FNVRYLREIIGVVSQEPVLFSTTIAENIRYGRGNVTMEEIKKAVKEAN-AYEFIMKLPQK 521

Query: 537 DAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVRE 596
              L   + ++LS GQK+R  IA  L   P +LL+DE  + LDT +   V   + +  RE
Sbjct: 522 FDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDK-ARE 580

Query: 597 AGITAVIITHRPEVVKALD 615
            G T ++I HR   V+  D
Sbjct: 581 -GRTTIVIAHRLSTVRNAD 598


>pir||H70788 probable peptidetransport system ABC-transporter ATP-binding
           protein - Mycobacterium tuberculosis (strain H37RV)
           >gi|2960087|emb|CAA17985.1| (AL022121) dppD
           [Mycobacterium tuberculosis]
           Length = 548
           
 Score = 75.3 bits (182), Expect = 2e-12
 Identities = 60/230 (26%), Positives = 107/230 (46%), Gaps = 34/230 (14%)

Query: 427 GVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGK 486
           G   R ++   +  ++F +     +A+VG SG+GK+TL R++LG ++        PTSG 
Sbjct: 296 GAPWRRVESRAVDGVSFRLPRASTLAIVGESGSGKSTLARMVLGLLQ--------PTSGT 347

Query: 487 IEVPKNAKVSVLIPGEI------------------EPEFGSETILE------HVYRKIRD 522
           +       V  L   ++                  +P +     +E      HV  + + 
Sbjct: 348 VVFDGTYDVGALARDQVLAFRRRVQPVFQNPYSSLDPMYSVFRAIEEPLRVHHVGDRRQR 407

Query: 523 LNAAVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLT 582
             A  E++++  L  ++L R    ELS GQ++R  IA  LA RP VL+ DE  + LD L 
Sbjct: 408 QRAVRELVDQVALPSSILGRRP-RELSGGQRQRVAIARALALRPEVLVCDEAVSALDVLV 466

Query: 583 AMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKS 632
             ++   ++++  + G+T + I+H   V++ +  D VL +  G V+   S
Sbjct: 467 QAQILDLLADLQADLGLTYLFISHDLAVIRQI-ADDVLVMRAGRVVEHAS 515


>pir||JE0248 ATP-binding cassette half-transporter - rat
           >gi|2982567|emb|CAA05793.1| (AJ003004) ABC transporter
           [Rattus norvegicus]
           Length = 836
           
 Score = 75.3 bits (182), Expect = 2e-12
 Identities = 58/215 (26%), Positives = 113/215 (51%), Gaps = 31/215 (14%)

Query: 435 RPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKI-----EV 489
           R  L++++FT+ PG+ VA+VG SGAGK+T+LRL+           Y  +SG I     ++
Sbjct: 603 RETLQDVSFTVMPGQTVALVGPSGAGKSTILRLLF--------RFYDISSGCIRIDGQDI 654

Query: 490 PKNAKVSVLIPGEIEPE---FGSETILEHV-YRKIRDLNAAVE-VLNRAGLSDAVL---- 540
            +  ++S+     + P+     ++TI  ++ Y ++   ++ ++     AG+ DA+L    
Sbjct: 655 SQVTQISLRSHIGVVPQDTVLFNDTIANNIRYGRVTAGDSEIQAAAQAAGIHDAILSFPE 714

Query: 541 -YRAKFSE----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVR 595
            Y  +  E    LS G+K+R  IA  + + P+++L+DE  + LDT     +   ++++  
Sbjct: 715 GYETQVGERGLKLSGGEKQRVAIARTILKAPDIILLDEATSALDTSNERAIQASLAKVCT 774

Query: 596 EAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVR 630
               T +++ HR   V  ++ D++L +  G +I R
Sbjct: 775 NR--TTIVVAHRLSTV--VNADQILVIKDGCIIER 805


>gb|AAD29692.1|AF135793_1 (AF135793) sister of P-glycoprotein [Fundulus heteroclitus]
           Length = 765
           
 Score = 75.3 bits (182), Expect = 2e-12
 Identities = 63/210 (30%), Positives = 99/210 (47%), Gaps = 33/210 (15%)

Query: 437 VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVS 496
           VL  LN ++ PG+ +A VG+SG GK+T  +L+        E  Y P  GK+ +  +    
Sbjct: 539 VLNGLNVSVRPGQTLAFVGSSGCGKSTSAQLL--------ERFYDPDHGKVLIDGHESTR 590

Query: 497 VLIP------GEI--EPEFGSETILEHV-----YRKIRDLNAAVEVLNRAGLSDAVL--- 540
           V +P      G +  EP     +I E++      R+I  +N  +    +A L D V+   
Sbjct: 591 VSVPFLRSKIGIVSQEPVLFDCSIAENIKYGDNLREI-SMNEVISAAKKAQLHDFVMSLP 649

Query: 541 --YRAKF----SELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIV 594
             Y A      S+LS GQK+R  IA  +   P +LL+DE  + LDT +   V   + +  
Sbjct: 650 EKYDANVGSQGSQLSRGQKQRIAIARAIIRDPKILLLDEATSALDTESEKTVQEALDK-- 707

Query: 595 REAGITAVIITHRPEVVKALDPDKVLFVGY 624
           R  G T ++I HR   ++  D   V+  G+
Sbjct: 708 RREGRTCIVIAHRLSTIQNSDIIAVMSRGF 737


>gb|AAD41366.1|AF151698_3 (AF151698) GlnP/GlnQ homolog [Agrobacterium tumefaciens]
           Length = 502
           
 Score = 75.3 bits (182), Expect = 2e-12
 Identities = 70/237 (29%), Positives = 115/237 (47%), Gaps = 32/237 (13%)

Query: 408 SELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRL 467
           S +  KG   +++ L  A+G         VL+ ++ ++ PG V  ++G SG+GK+TLLR 
Sbjct: 257 SGVAFKGGSLDVRRLGMAYG------DLDVLKGVDLSVKPGSVTCIIGPSGSGKSTLLRG 310

Query: 468 ILGAIKGYWEEKYRPTSGKIEV---------PKNAKVSVLIPGEIEPEFGSETILEHV-- 516
           +   ++        P SG I +         P+  +  V +  +    F   T LE+V  
Sbjct: 311 LNRLVE--------PKSGDILIDGESILAMKPETLRRRVGMVFQHFNLFPDHTALENVML 362

Query: 517 -YRKIRDLNAA-VEVLNRAGLSDAVLYRAKFSE---LSTGQKERAKIASLLAERPNVLLI 571
             +KI+ L AA  E + +AGL+D  L   +      LS GQ++R  IA  LA  P V+L 
Sbjct: 363 SLKKIKGLPAAEAERIAKAGLADVGLASRQHHRPGGLSGGQQQRVAIARALAMEPEVILF 422

Query: 572 DEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
           DE  + LD      V   ++E+    G+T V++TH     + +  D+V+F+  G V+
Sbjct: 423 DEVTSALDPELVKGVLNLMAEL-GTRGMTMVVVTHEMGFARRV-ADQVVFMDEGRVV 477


>pir||H81391 amino-acid ABC transporter ATP-binding protein Cj0469 [imported] -
           Campylobacter jejuni (strain NCTC 11168)
           >gi|6967940|emb|CAB75107.1| (AL139075) amino-acid ABC
           transporter ATP-binding protein [Campylobacter jejuni]
           Length = 253
           
 Score = 75.3 bits (182), Expect = 2e-12
 Identities = 70/231 (30%), Positives = 106/231 (45%), Gaps = 38/231 (16%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           +I++L K +G  H       L+++N  +   EVV ++G SG GK+TLLR I G      E
Sbjct: 5   KIENLQKYYGSHH------ALKDINLEVKAKEVVVILGPSGCGKSTLLRCINGL-----E 53

Query: 478 EKYRPTSGKI-----EVPKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLNR 532
           E     SG I     ++ K+ K    +  ++   F S  + EH+  +   L   ++V  R
Sbjct: 54  E---IASGNIYIDNEKIDKDFKEWPRMRQKVGMVFQSYELFEHLSVEENILLGPMKVQKR 110

Query: 533 AGLSDAVLYRAKF---------------SELSTGQKERAKIASLLAERPNVLLIDEFAAH 577
               D VL  AK                 ELS GQK+R  I   L   P ++L DE  A 
Sbjct: 111 K--KDEVLKEAKIWLEKVGLLHKIHAYPRELSGGQKQRIAIVRSLCMNPELMLFDEVTAA 168

Query: 578 LDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
           LD      V   +  + +E G+T +I+TH     KA+  DK++F+  G +I
Sbjct: 169 LDPEIVREVLEVMLNLAKE-GMTMLIVTHEMGFAKAV-ADKIIFMDEGKII 217


>gb|AAG26952.1|AC069471_13 (AC069471) P-glycoprotein, putative [Arabidopsis thaliana]
            Length = 1245
            
 Score = 75.3 bits (182), Expect = 2e-12
 Identities = 70/261 (26%), Positives = 122/261 (45%), Gaps = 56/261 (21%)

Query: 384  KPSYGKVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNF 443
            +P+   V  ++G I F+NV+ V+ +  +I                        + +NLN 
Sbjct: 991  QPNSRMVSQVKGDIEFRNVSFVYPTRPEID-----------------------IFKNLNL 1027

Query: 444  TINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVP-KNAKV------- 495
             ++ G+ +AVVG SG+GK+T++ LI+          Y P++G + +  ++ K        
Sbjct: 1028 RVSAGKSLAVVGPSGSGKSTVIGLIM--------RFYDPSNGNLCIDGQDIKTLNLRSLR 1079

Query: 496  SVLIPGEIEPEFGSETILEHVYRKIRDLNAA-VEVLNRAGLSDAVLYRAKFSE------- 547
              L   + EP   S TI E++  K  + NA+  E++  A  ++A  +  K  E       
Sbjct: 1080 KKLALVQQEPALFSTTIYENI--KYGNENASEAEIMEAAKAANAHEFIIKMEEGYKTHAG 1137

Query: 548  -----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAV 602
                 LS GQK+R  IA  + + P+VLL+DE  + LDT +   V   + ++++  G T V
Sbjct: 1138 DKGVQLSGGQKQRVAIARAVLKDPSVLLLDEATSALDTSSEKLVQEALDKLMK--GRTTV 1195

Query: 603  IITHRPEVVKALDPDKVLFVG 623
            ++ HR   ++  D   VL  G
Sbjct: 1196 LVAHRLSTIRKADTVAVLHKG 1216


>gb|AAG34709.1|AF320001_2 (AF320001) putative ATP binding protein of ABC transporter
           [Acinetobacter sp. BD413]
           Length = 228
           
 Score = 74.9 bits (181), Expect = 3e-12
 Identities = 62/223 (27%), Positives = 108/223 (47%), Gaps = 40/223 (17%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E +D+ K F      ++  V++ L+  I  GE V++VGASG+GK+TLL  ILG +     
Sbjct: 7   EAKDVYKHFTDGKSTVE--VIKGLSLKIAAGEFVSIVGASGSGKSTLLH-ILGGLD---- 59

Query: 478 EKYRPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEHVYR------------------- 518
              +PT G++ + +    ++   GE E  F     L  VY+                   
Sbjct: 60  ---QPTQGQVFLNEQRFDNL---GEAERGFKRNQYLGFVYQFHHLLPEFSALENVAMPLM 113

Query: 519 -----KIRDLNAAVE-VLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLID 572
                  +++    E +L+R GLS  + ++    ELS G+++R  +A  L  RP V+L D
Sbjct: 114 LRADTNYKEVKQQAEHLLDRVGLSHRLTHKP--GELSGGERQRVALARALVARPAVMLAD 171

Query: 573 EFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALD 615
           E   +LD  TA  +   +S++ +E  +  +I+TH  ++ ++ D
Sbjct: 172 EPTGNLDRKTAFGIFELLSDLKQEFNMAMLIVTHDEQLAQSAD 214


>sp|P36372|TAP2_RAT ANTIGEN PEPTIDE TRANSPORTER 2 (APT2) >gi|111976|pir||S19603 mtp 2
           protein - rat >gi|56719|emb|CAA45339.1| (X63854) mtp2a
           [Rattus norvegicus] >gi|228306|prf||1802394A MHC-linked
           transporter [Rattus norvegicus] >gi|228757|prf||1810434A
           MHC-linked transporter mtp2 [Rattus sp.]
           Length = 703
           
 Score = 74.9 bits (181), Expect = 3e-12
 Identities = 66/236 (27%), Positives = 115/236 (47%), Gaps = 38/236 (16%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E QD+  ++  R    ++PVL+ L FT++PG+V A+VG +G+GK+T+  L+        +
Sbjct: 469 EFQDVSFSYPSRP---EKPVLQGLTFTLHPGKVTALVGPNGSGKSTVAALL--------Q 517

Query: 478 EKYRPTSGKIEVPKNAKV---------SVLIPGEIEPEFGSETILEHVYRKIRDL-NAAV 527
             Y+PT G++ +     V          V++ G+ EP   S ++ +++   +RD  +A V
Sbjct: 518 NLYQPTGGQLLLDGEPLVQYDHHYLHRQVVLVGQ-EPVLFSGSVKDNIAYGLRDCEDAQV 576

Query: 528 EVLNRAGLSDAVL----------YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAH 577
               +A  +D  +             K S+L+ GQK+R  IA  L   P VL++DE  + 
Sbjct: 577 MAAAQAACADDFIGEMTNGINTEIGEKGSQLAVGQKQRLAIARALVRNPRVLILDEATSA 636

Query: 578 LDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
           LD      +    S+  R    T ++I HR   V+  + D+VL +  G ++    L
Sbjct: 637 LDAECEQALQTWRSQEDR----TMLVIAHRLHTVQ--NADQVLVLKQGQLVEHDQL 686


>pir||B71077 probable ABC transporter ATP-binding protein - Pyrococcus
           horikoshii >gi|3257293|dbj|BAA29976.1| (AP000004) 237aa
           long hypothetical ABC transporter ATP-binding protein
           [Pyrococcus horikoshii]
           Length = 237
           
 Score = 74.9 bits (181), Expect = 3e-12
 Identities = 57/215 (26%), Positives = 105/215 (48%), Gaps = 25/215 (11%)

Query: 428 VRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKI 487
           V +RV  R ++  +N     G   +++G +GAGK+T+  +++G +K        P+ G++
Sbjct: 7   VTYRVDGRRIIERINMRFKEGMTYSILGPNGAGKSTIAYILMGVMK--------PSEGRV 58

Query: 488 ----------EVPKNAKVSVLIPGEIEPEFGSETILEHVY--RKIR-DLNAAVEVLNRAG 534
                      + + A++ + +  +    +   T+ +++    KI+ D N   E+L   G
Sbjct: 59  LLDGDDITNLSITERARLGITLLWQEPARYDGITVEKYLTLGGKIKVDKNEMREILELVG 118

Query: 535 LS-DAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEI 593
           L  +   +R     LS G+++R ++AS+L  RP   ++DE  + LD +TA  +   V E 
Sbjct: 119 LPYELYAHRFVDKSLSGGERKRIELASILMLRPRYAILDEPDSGLD-ITAGELIENVLEY 177

Query: 594 VREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
            R  G T ++ITH  E+  A   D   FV  G +I
Sbjct: 178 FRRVGTTVILITHHEEI--AAKTDFAYFVCAGRII 210


>gb|AAF65552.1|AF249879_1 (AF249879) liver bile salt export pump [Oryctolagus cuniculus]
           Length = 1321
           
 Score = 74.9 bits (181), Expect = 3e-12
 Identities = 68/247 (27%), Positives = 107/247 (42%), Gaps = 54/247 (21%)

Query: 389 KVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPG 448
           K+E ++G I F NVT  + S  ++K                       +L NL+  I PG
Sbjct: 412 KLERIKGEIEFHNVTFHYPSRPEVK-----------------------ILNNLSMVIKPG 448

Query: 449 EVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVSVLIP------GE 502
           E+ A+VG SGAGK+T L+LI           Y PT G + V  +   S  I       G 
Sbjct: 449 EMTALVGPSGAGKSTALQLI--------HRFYGPTEGMVTVESHDIRSSHIQWLRNQIGI 500

Query: 503 IEPE-------------FGSE-TILEHVYRKIRDLNAAVEVLNRAGLSDAVLYRAKFSEL 548
           +E E             +G E   +E + +  ++ NA   +++     D ++      ++
Sbjct: 501 VEQEPVLFFHTIAEKIRYGREDATMEDLIQAAKEANAYNFIMDLPQQFDTLVGEGG-GQM 559

Query: 549 STGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRP 608
           S GQK+R  IA  L   P +LL+D   + LD  +   V   +S+   + G T V + HRP
Sbjct: 560 SGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEALSK--TQHGHTIVSVAHRP 617

Query: 609 EVVKALD 615
             ++  D
Sbjct: 618 ATIRTAD 624


>sp|P77279|YBBL_ECOLI HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN YBBL
           >gi|7430366|pir||A64780 probable ABC ransport protein
           ybbL - Escherichia coli >gi|1773172|gb|AAB40244.1|
           (U82664) hypothetical protein [Escherichia coli]
           >gi|1786698|gb|AAC73592.1| (AE000155) putative
           ATP-binding component of a transport system [Escherichia
           coli K12]
           Length = 225
           
 Score = 74.5 bits (180), Expect = 3e-12
 Identities = 61/215 (28%), Positives = 97/215 (44%), Gaps = 27/215 (12%)

Query: 417 QEIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYW 476
           QE   LL+   V +      +L N+NF++  GE   + G SG GK+TLL+++   I    
Sbjct: 2   QENSPLLQLQNVGYLAGDAKILNNINFSLRAGEFKLITGPSGCGKSTLLKIVASLIS--- 58

Query: 477 EEKYRPTSGKIEVPKNAKVSVLIPGEI----------EPEFGSETILEH------VYRKI 520
                PTSG + + +   VS L P EI           P    +T+ ++      +  + 
Sbjct: 59  -----PTSGTL-LFEGEDVSTLKP-EIYRQQVSYCAQTPTLFGDTVYDNLIFPWQIRNRQ 111

Query: 521 RDLNAAVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDT 580
            D    ++ L R  L D++L +   +ELS G+K+R  +   L   P VLL+DE  + LD 
Sbjct: 112 PDPAIFLDFLERFALPDSILTK-NIAELSGGEKQRISLIRNLQFMPKVLLLDEITSALDE 170

Query: 581 LTAMRVARKVSEIVREAGITAVIITHRPEVVKALD 615
                V   +   VRE  I  + +TH  + +   D
Sbjct: 171 SNKHNVNEMIHRYVREQNIAVLWVTHDKDEINHAD 205


>sp|P38053|SSUB_ECOLI PUTATIVE ALIPHATIC SULFONATES TRANSPORT ATP-BINDING PROTEIN SSUB
           >gi|7445682|pir||D64833 probable ABC-type transport
           protein ycbE - Escherichia coli
           >gi|1787164|gb|AAC74019.1| (AE000195) putative
           ATP-binding component of a transport system [Escherichia
           coli K12] >gi|4062499|dbj|BAA35685.1| (D90731)
           Hypothetical abc transporter ATP-binding protein in pepN
           3'region . [Escherichia coli]
           >gi|4062501|dbj|BAA35688.1| (D90732) Hypothetical abc
           transporter ATP-binding protein in pepN 3'region .
           [Escherichia coli] >gi|4583570|emb|CAB40393.1|
           (AJ237695) putative aliphatic sulfonate transport
           ATP-binding protein [Escherichia coli]
           Length = 255
           
 Score = 74.5 bits (180), Expect = 3e-12
 Identities = 61/195 (31%), Positives = 93/195 (47%), Gaps = 13/195 (6%)

Query: 437 VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVS 496
           VL  L+  I  G+ VAVVG SG GK+TLLRL+ G       +    T+   E+ ++ ++ 
Sbjct: 26  VLNQLDLHIPAGQFVAVVGRSGGGKSTLLRLLAGLETPTAGDVLAGTTPLAEIQEDTRMM 85

Query: 497 V----LIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLNRAGLSDAVLYRAKFSELSTGQ 552
                L+P +   +     +        R   AAV + NRAG   A L        S GQ
Sbjct: 86  FQDARLLPWKSVIDNVGLGLKGQWRDAARRALAAVGLENRAGEWPAAL--------SGGQ 137

Query: 553 KERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVK 612
           K+R  +A  L  RP +LL+DE    LD LT + +   +  + +E G T +++TH      
Sbjct: 138 KQRVALARALIHRPGLLLLDEPLGALDALTRLEMQDLIVSLWQEHGFTVLLVTHDVSEAV 197

Query: 613 ALDPDKVLFVGYGTV 627
           A+  D+VL +  G +
Sbjct: 198 AM-ADRVLLIEEGKI 211


>gb|AAC18099.1| (AF058302) ATPase component of putative ABC transporter
           [Streptomyces roseofulvus]
           Length = 524
           
 Score = 74.5 bits (180), Expect = 3e-12
 Identities = 61/204 (29%), Positives = 96/204 (46%), Gaps = 20/204 (9%)

Query: 420 QDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEK 479
           +DL+K +    R ++   +  + FT+  GE  A+VG SG+GK+T  RL+ G         
Sbjct: 285 RDLVKEYRRDGRRVR--AVDGVGFTVREGEFFALVGESGSGKSTTARLVTGLTA------ 336

Query: 480 YRPTSGKIE---VPKNAKVSVLIP-GEIEPEFGSETILEHVYRK-----IRDLNAAVEVL 530
             PTSG +E    P   ++    P    +P +    I+E   R       R      E+L
Sbjct: 337 --PTSGAVEHAPAPVRPQLVQQSPYAAFDPRWTVRRIVEEPLRARHVPGARRRARLRELL 394

Query: 531 NRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKV 590
              GL + +L R    ELS GQ++R  +A  LA  P +L+  E  A LD +   RV   +
Sbjct: 395 ALVGLDEELLARRP-RELSGGQRQRVALARALAPEPRLLVCGEPVAALDPVARERVVHLL 453

Query: 591 SEIVREAGITAVIITHRPEVVKAL 614
             +  E G+T + ++H  +VV+ L
Sbjct: 454 ERLRAELGLTCLFVSHELDVVRRL 477


>gb|AAC64256.1| (AF042861) putative OppF [Treponema denticola]
           Length = 385
           
 Score = 74.5 bits (180), Expect = 3e-12
 Identities = 58/201 (28%), Positives = 96/201 (46%), Gaps = 19/201 (9%)

Query: 441 LNFTINPGEVVAVVGASGAGKTTLLRLILGAIK--------------GYWEEKYRPTSGK 486
           ++  I+ GE V +VG SG GK+TL R IL   K               Y   +  P   K
Sbjct: 91  IDLVIHEGETVGLVGESGCGKSTLGRTILKLYKPTAGEIFFEGENITNYTVTQMMPLRKK 150

Query: 487 IEVPKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDL---NAAVEVLNRAGLSDAVLYRA 543
           +++      S L P     +   E +LEH   K +D        E++N  GL+D ++YR 
Sbjct: 151 MQIIFQDPYSSLNPKMTVGQIIGEALLEHGMFKKKDPAYEKYVKEIMNTCGLADYMIYRY 210

Query: 544 KFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVI 603
              E S GQ++R  IA  LA +P  ++ DE  + LD     ++   ++++ +E  ++ + 
Sbjct: 211 PH-EFSGGQRQRIGIARALALKPKFIVCDEAVSALDVSIQSQIINLLNDLQKEFNLSYLF 269

Query: 604 ITHRPEVVKAL-DPDKVLFVG 623
           I+H   VVK + D   V+++G
Sbjct: 270 ISHDLSVVKHISDRIGVMYLG 290


>emb|CAB69727.1| (AL137166) putative metal transport ABC transporter [Streptomyces
           coelicolor A3(2)]
           Length = 256
           
 Score = 74.5 bits (180), Expect = 3e-12
 Identities = 59/200 (29%), Positives = 97/200 (48%), Gaps = 18/200 (9%)

Query: 420 QDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIK------ 473
           + ++   GVR  +  RPVLR ++ T+  G+VVA++GA+G+GK+T +R I+G +       
Sbjct: 4   ESVISLRGVRAELGSRPVLRGIDLTVRRGQVVALLGANGSGKSTAVRTIIGQVPVTAGEI 63

Query: 474 ---GYWEEKYRPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEHVYRKIR--DLNAAVE 528
              G    ++R  +    VP+    +  +P  +     S  +    +  +R  D  A   
Sbjct: 64  ELFGTPRRRFRDWARVGYVPQRTTAAGGVPATVTEVVSSGRLSRARFGVLRKADHEAVRR 123

Query: 529 VLNRAGLSDAVLYRAKFS--ELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRV 586
            L   G++D    RAK S   LS GQ +R  IA  LA  P +L++DE  A +D L +  V
Sbjct: 124 ALGLVGMAD----RAKDSVNALSGGQHQRVLIARALAAEPELLIMDEPMAGVD-LASQEV 178

Query: 587 ARKVSEIVREAGITAVIITH 606
             +       AG T +++ H
Sbjct: 179 LAETLRGQVAAGTTVLLVLH 198


>gb|AAA93553.1| (L23922) P-glycoprotein 5 [Entamoeba histolytica]
            Length = 1301
            
 Score = 74.1 bits (179), Expect = 4e-12
 Identities = 61/210 (29%), Positives = 105/210 (49%), Gaps = 34/210 (16%)

Query: 437  VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVP----KN 492
            VL+ ++F  + G+ +A+VGASG GK+T ++L+        E  Y PTSG++ +     K+
Sbjct: 1073 VLKGISFKADQGKTIALVGASGCGKSTTIQLV--------ERFYDPTSGEVLLDGYNIKD 1124

Query: 493  AKVSVL-----IPGEIEPEFGSETILEHVYRKIRD--------LNAAVEVLNRAGLSDAV 539
              V  L     + G+ EP   +E++++++ R + +        + AA ++ N      A+
Sbjct: 1125 LNVKFLRNQIGLVGQ-EPVLFAESVIDNIKRGVPEGVEVSNEQIYAAAKMANAHDFISAM 1183

Query: 540  ------LYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEI 593
                  +   + S+LS GQK+R  IA  L   P VLL+DE  + LDT +   V   + + 
Sbjct: 1184 PEGYNTMVGDRGSQLSGGQKQRIAIARALIRNPKVLLLDEATSALDTQSEKIVQDALDKA 1243

Query: 594  VREAGITAVIITHRPEVVKALDPDKVLFVG 623
             +  G T +II HR   ++  D   V+  G
Sbjct: 1244 SK--GRTTIIIAHRLSTIQNADQICVIMRG 1271


>pir||A49933 proteinase SM transporter PrtD - Serratia marcescens
           >gi|452928|gb|AAB28772.1| (S67013) protease SM
           transporter, PrtD SM transporter=inner membrane
           metalloprotease transporter [Serratia marcescens, 365,
           Peptide, 576 aa]
           Length = 576
           
 Score = 74.1 bits (179), Expect = 4e-12
 Identities = 59/198 (29%), Positives = 98/198 (48%), Gaps = 21/198 (10%)

Query: 436 PVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKV 495
           PVL  ++F +  GEV+ V+GASG+GKT L+R ++GA+         P SG     +    
Sbjct: 337 PVLHGVSFRLEAGEVLGVIGASGSGKTLLMRQLVGAL--------TPISGDGGAEQLGPH 388

Query: 496 SVLIPGEIEPEFGSETILEHVYRKIR-DLNAAVEVLNRAGLSDAVLYRAKFSE------- 547
              +P +I+   G  T+ +++ R  + D    V     AG+   +L+  K  E       
Sbjct: 389 IGYLPQDIQLFAG--TLTDNIARFGQVDAEKVVAAAALAGVHQLILHLPKGYETELGEGG 446

Query: 548 --LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIIT 605
             LS GQ++R  +A  L   P ++++DE  A+LD      + R + E ++  G T V++T
Sbjct: 447 SGLSGGQRQRVALARALYGSPALVVLDEPNANLDREGEEALQRAI-EALKARGNTIVLVT 505

Query: 606 HRPEVVKALDPDKVLFVG 623
           H+P ++   D   VL  G
Sbjct: 506 HKPAILATTDKLLVLTAG 523


>pir||T48672 ABC-type transport system ATP-binding protein hasD [validated] -
           Serratia marcescens >gi|1885340|emb|CAA57069.1| (X81195)
           hasD [Serratia marcescens]
           Length = 586
           
 Score = 74.1 bits (179), Expect = 4e-12
 Identities = 59/198 (29%), Positives = 98/198 (48%), Gaps = 21/198 (10%)

Query: 436 PVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKV 495
           PVL  ++F +  GEV+ V+GASG+GKT L+R ++GA+         P SG     +    
Sbjct: 347 PVLHGVSFRLEAGEVLGVIGASGSGKTLLMRQLVGAL--------TPISGDGGAEQLGPH 398

Query: 496 SVLIPGEIEPEFGSETILEHVYRKIR-DLNAAVEVLNRAGLSDAVLYRAKFSE------- 547
              +P +I+   G  T+ +++ R  + D    V     AG+   +L+  K  E       
Sbjct: 399 IGYLPQDIQLFAG--TLTDNIARFGQVDAEKVVAAAALAGVHQLILHLPKGYETELGEGG 456

Query: 548 --LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIIT 605
             LS GQ++R  +A  L   P ++++DE  A+LD      + R + E ++  G T V++T
Sbjct: 457 SGLSGGQRQRVALARALYGSPALVVLDEPNANLDREGEEALQRAI-EALKARGNTIVLVT 515

Query: 606 HRPEVVKALDPDKVLFVG 623
           H+P ++   D   VL  G
Sbjct: 516 HKPAILATTDKLLVLTAG 533


>pir||E75120 hypothetical protein PAB1855 - Pyrococcus abyssi (strain Orsay)
           >gi|5458189|emb|CAB49678.1| (AJ248285) hypothetical
           protein [Pyrococcus abyssi]
           Length = 247
           
 Score = 74.1 bits (179), Expect = 4e-12
 Identities = 56/217 (25%), Positives = 103/217 (46%), Gaps = 26/217 (11%)

Query: 422 LLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYR 481
           +LK   +   V  R +LR +N  +N GE   ++G +G+GK+TL   I G        KY+
Sbjct: 1   MLKIEDLHVEVEGREILRGINLAVNDGEFHVIMGPNGSGKSTLALTIAG------HPKYK 54

Query: 482 PTSGKI----------EVPKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDL------NA 525
            T GKI             + A+  +L+  ++ PE     IL+ + + + ++       A
Sbjct: 55  VTKGKIIFNGEDITSSSPDERARKGILLAFQVPPEIEGVRILDFLIQVLTEIKGMKPEEA 114

Query: 526 AVEVLNRA---GLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLT 582
              VLN+A      D  + R      S G+++R ++   L   P +LL+DE  + +D  +
Sbjct: 115 YDVVLNKAKELWFDDKDMRRFVNVGFSGGERKRLELLQALLLEPKLLLLDEPDSGVDVDS 174

Query: 583 AMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKV 619
              ++RK+ E+    G++ ++ITH   +   +D +K+
Sbjct: 175 LSVISRKIEEL-HNRGVSIILITHYGRIFGHIDKEKL 210


>emb|CAB76006.1| (AL157916) putative ABC transporter, ATP-binding subunit
           [Streptomyces coelicolor A3(2)]
           Length = 312
           
 Score = 74.1 bits (179), Expect = 4e-12
 Identities = 64/224 (28%), Positives = 106/224 (46%), Gaps = 35/224 (15%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E+ DL K++G       RPV+  ++F +  GE+  V+G +GAGKTT +  + G       
Sbjct: 17  EVTDLRKSYG------GRPVVDGVSFAVEEGEIFGVLGPNGAGKTTTVECVEGL------ 64

Query: 478 EKYRPTSGKIEVP---------KNAKV--SVLIPGEIEPEFGSETILE---HVYRKIRDL 523
               P +G++ V          + A+V  + L   E++P+      LE     Y K  D 
Sbjct: 65  --RVPDAGRVRVTGLDPVADHRRVAEVLGAQLQQSELQPKLTVREALELYAAFYPKPADW 122

Query: 524 NAAVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTA 583
               E L+   + D      +F++LS GQK+R  IA  L   P V+++DE    LD   A
Sbjct: 123 RPLAERLDLVPMLD-----TRFAKLSGGQKQRLFIALALVGDPRVVVLDELTTGLDP-RA 176

Query: 584 MRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTV 627
            R   ++ E +R  G+T +++TH  E  + L  D++  +  G +
Sbjct: 177 RRETWQLIEDIRAGGVTVLLVTHFMEEAQRL-CDRIAVIDRGRI 219


>pir||S25577 mt2 protein - rat
           Length = 703
           
 Score = 73.7 bits (178), Expect = 6e-12
 Identities = 65/236 (27%), Positives = 115/236 (48%), Gaps = 38/236 (16%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E QD+  ++  R    ++PVL+ L FT++PG+V A+VG +G+GK+T+  L+        +
Sbjct: 469 EFQDVSFSYPSRP---EKPVLQGLTFTLHPGKVTALVGPNGSGKSTVAALL--------Q 517

Query: 478 EKYRPTSGKIEVPKNAKV---------SVLIPGEIEPEFGSETILEHVYRKIRDL-NAAV 527
             Y+PT G++ +     V          V++ G+ EP   S ++ +++   +RD  +A V
Sbjct: 518 NLYQPTGGQLLLDGEPLVQYDHHYLHRQVVLVGQ-EPVLFSGSVKDNIAYGLRDCEDAQV 576

Query: 528 EVLNRAGLSDAVL----------YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAH 577
               +A  +D  +             + S+L+ GQK+R  IA  L   P VL++DE  + 
Sbjct: 577 MAAAQAACADDFIGEMTNGINTEIGERGSQLAVGQKQRLAIARALVRNPRVLILDEATSA 636

Query: 578 LDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
           LD      +    S+  R    T ++I HR   V+  + D+VL +  G ++    L
Sbjct: 637 LDAECEQALQTWRSQEDR----TMLVIAHRLHTVQ--NADQVLVLKQGQLVEHDQL 686


>gb|AAA50516.1| (M77784) transport protein [Agrobacterium tumefaciens]
           Length = 262
           
 Score = 73.7 bits (178), Expect = 6e-12
 Identities = 68/233 (29%), Positives = 116/233 (49%), Gaps = 33/233 (14%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLI-------LG 470
           +++D+ K FG         VL  ++ + N GEV++++G+SG+GK+TLLR +        G
Sbjct: 10  QLKDIRKNFG------NLEVLHGVSLSANEGEVISILGSSGSGKSTLLRCVNMLEVPNAG 63

Query: 471 AIKGYWEE-KYRPTSGKIEVPKNAKVSVLIPGEIEPEF------GSETILEH-----VYR 518
           ++    EE      +G++  PK+ K    +       F        +TIL++     V+ 
Sbjct: 64  SVAIMGEEIALEHRAGRLARPKDLKQVNRLRERAAMVFQGFNLWSHQTILQNVMEAPVHV 123

Query: 519 KIRDLNA----AVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEF 574
           + RD  A    A  +L R G++      A  SELS GQ++RA IA  LA RP+V+L DE 
Sbjct: 124 QGRDRKACRDEAEALLERVGIAPNA--NAYPSELSGGQQQRAAIARALAMRPDVMLFDEP 181

Query: 575 AAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTV 627
            + LD      V + + ++  E G T +I+TH  +  + +   + +F+  G +
Sbjct: 182 TSALDPELVGEVLKVMRDLAAE-GRTMLIVTHEMDFARDVS-SRTVFLHQGVI 232


>pir||S38400 mt2 protein - rat >gi|407477|emb|CAA53053.1| (X75305) TAP2 [Rattus
           norvegicus]
           Length = 703
           
 Score = 73.7 bits (178), Expect = 6e-12
 Identities = 65/236 (27%), Positives = 115/236 (48%), Gaps = 38/236 (16%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E QD+  ++  R    ++PVL+ L FT++PG+V A+VG +G+GK+T+  L+        +
Sbjct: 469 EFQDVSFSYPSRP---EKPVLQGLTFTLHPGKVTALVGPNGSGKSTVAALL--------Q 517

Query: 478 EKYRPTSGKIEVPKNAKV---------SVLIPGEIEPEFGSETILEHVYRKIRDL-NAAV 527
             Y+PT G++ +     V          V++ G+ EP   S ++ +++   +RD  +A V
Sbjct: 518 NLYQPTGGQLLLDGEPLVQYDHHYLHRQVVLVGQ-EPVLFSGSVKDNIAYGLRDCEDAQV 576

Query: 528 EVLNRAGLSDAVL----------YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAH 577
               +A  +D  +             + S+L+ GQK+R  IA  L   P VL++DE  + 
Sbjct: 577 MAAAQAACADDFIGEMTNGINTEIGERGSQLAVGQKQRLAIARALVRNPRVLILDEATSA 636

Query: 578 LDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
           LD      +    S+  R    T ++I HR   V+  + D+VL +  G ++    L
Sbjct: 637 LDAECEQALQTWRSQEDR----TMLVIAHRLHTVQ--NADQVLVLKQGQLVEHDQL 686


>emb|CAA67415.1| (X98917) orf4 [Methanopyrus kandleri]
           Length = 228
           
 Score = 73.7 bits (178), Expect = 6e-12
 Identities = 54/213 (25%), Positives = 101/213 (47%), Gaps = 21/213 (9%)

Query: 422 LLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYR 481
           +L+  GV+     R VLR ++  + PGEV  + G +G+GK+TLL+++ G +        R
Sbjct: 1   MLRVEGVKFSYGDREVLRGVDLEVEPGEVRVLFGPNGSGKSTLLKIVAGIL--------R 52

Query: 482 PTSGKI--------EVPKNAKVSVLIPGE--IEPEFGSETILEHVYRKIR-DLNAAVEVL 530
           P  G++        ++P   +    +P +  + P    E  + +  +  R D +   E++
Sbjct: 53  PDEGRVIIGEEDVTDLPPEERHVGYVPQQPALFPHMTVEDNITYSLQNGRGDPDRLDELV 112

Query: 531 NRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKV 590
              GL + +    K  ELS G + R  +A  L   P V+L+DE  + +D      +  + 
Sbjct: 113 ELLGLKEHL--DRKPDELSGGYQSRVSLARALFSDPKVMLLDEPLSDVDLAVKAGLVPRF 170

Query: 591 SEIVREAGITAVIITHRPEVVKALDPDKVLFVG 623
            E+++E GI A+ +TH P   + +     + +G
Sbjct: 171 REVLKETGIPALYVTHDPWEAERIGDSFTVLIG 203


>pir||T04251 P-glycoprotein 2 - Arabidopsis thaliana >gi|2108252|emb|CAA71277.1|
           (Y10228) P-glycoprotein-2 [Arabidopsis thaliana]
           >gi|2108254|emb|CAA71276.1| (Y10227) P-glycoprotein-2
           [Arabidopsis thaliana] >gi|4538925|emb|CAB39661.1|
           (AL049483) P-glycoprotein-2 (pgp2) [Arabidopsis
           thaliana] >gi|7269447|emb|CAB79451.1| (AL161564)
           P-glycoprotein-2 (pgp2) [Arabidopsis thaliana]
           Length = 1233
           
 Score = 73.7 bits (178), Expect = 6e-12
 Identities = 62/208 (29%), Positives = 99/208 (46%), Gaps = 33/208 (15%)

Query: 437 VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVS 496
           +   LN  I  G++VA+VG SG+GK+T++ LI        E  Y P SG + +  N  +S
Sbjct: 378 IFDRLNLAIPAGKIVALVGGSGSGKSTVISLI--------ERFYEPISGAVLLDGN-NIS 428

Query: 497 VL----IPGEI-----EPEFGSETILEHVYRKIRDLNAAVEVLNRAGLSDAVLYRAKFSE 547
            L    + G+I     EP   + TI E++    +D   A E+   A LS+A+ +     E
Sbjct: 429 ELDIKWLRGQIGLVNQEPALFATTIRENILYG-KDDATAEEITRAAKLSEAISFINNLPE 487

Query: 548 ------------LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVR 595
                       LS GQK+R  I+  + + P++LL+DE  + LD  +   V   +  ++ 
Sbjct: 488 GFETQVGERGIQLSGGQKQRIAISRAIVKNPSILLLDEATSALDAESEKSVQEALDRVM- 546

Query: 596 EAGITAVIITHRPEVVKALDPDKVLFVG 623
             G T V++ HR   V+  D   V+  G
Sbjct: 547 -VGRTTVVVAHRLSTVRNADIIAVVHEG 573


>pir||T31072 heterocyst differentiation protein HetC - Anabaena sp
            >gi|2828798|gb|AAC38130.1| (U55386) HetC [Anabaena
            PCC7120]
            Length = 1044
            
 Score = 73.7 bits (178), Expect = 6e-12
 Identities = 59/217 (27%), Positives = 104/217 (47%), Gaps = 35/217 (16%)

Query: 434  QRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNA 493
            +R  L+N++F I P + + ++G SG+GK+TL  L+ G         YRP +G+I +  + 
Sbjct: 820  ERNALQNISFGIKPQQTIGIIGQSGSGKSTLANLLAGL--------YRPDTGRILIDGHD 871

Query: 494  KVSVLIPGEIEPEFG---------SETILEHVYRKIRDLN--AAVEVLNRAGLSDAVL-- 540
               V  P  +  + G         S TILE++    ++L+   A+      G  D +   
Sbjct: 872  MAGV-SPQSLRSQVGLVAQDSFLFSGTILENITLHDQELSLIQAIAAAKLTGAHDFIQAL 930

Query: 541  ---YRAKFSE----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEI 593
               Y  +  E    LS GQ+++  IA  L   P +L++DE  + LD  +  R  + +++I
Sbjct: 931  PLGYDTQVGERGFMLSGGQRQKIAIARALVRNPKILILDEATSGLDAESERRFQQNLAQI 990

Query: 594  VREAGITAVIITHRPEVVKALDP----DKVLFVGYGT 626
             +E   T  I++HR   V+  D     D+ + + +GT
Sbjct: 991  SQER--TTFIVSHRLSTVRYADHIFVIDQGMVIEHGT 1025


>pir||A75083 ATP-binding transport protein PAB1668 - Pyrococcus abyssi  (strain
           Orsay) >gi|5458478|emb|CAB49966.1| (AJ248286)
           ATP-BINDING TRANSPORT PROTEIN [Pyrococcus abyssi]
           Length = 315
           
 Score = 73.7 bits (178), Expect = 6e-12
 Identities = 65/206 (31%), Positives = 102/206 (48%), Gaps = 35/206 (16%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E ++L K FG R+      V+ NLN  +  G V   +G +GAGKTT ++++ GA+K    
Sbjct: 7   ETKELTKFFGKRN------VVYNLNLKVPKGAVYGFLGPNGAGKTTTIKMLTGALK---- 56

Query: 478 EKYRPTSGKI-----EVPKNAKVSVLIPGEIEPE----FGSETILEH-VYR-------KI 520
               PT G+I     E+P+  +V ++      PE    +   TI E  VY        K 
Sbjct: 57  ----PTYGEIKIIGMEMPRE-RVKIMRNVGYMPERPLAYDDMTIFEFLVYMGRLLGLPKD 111

Query: 521 RDLNAAVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDT 580
           + +N A E++   G+        K  ELS+GQ++R   AS L   P +L++DE  ++LD 
Sbjct: 112 KAVNQARELMAYTGVGRLAFN--KIEELSSGQRQRVLFASALMGDPELLILDEPTSNLDP 169

Query: 581 LTAMRVARKVSEIVREAGITAVIITH 606
           L  M    K+ E+ + +G T  I +H
Sbjct: 170 LGRMEFIGKILELAK-SGKTVFISSH 194


>pir||D81435 probable iron-uptake ABC transport system ATP-binding protein
           Cj0173c [imported] - Campylobacter jejuni (strain NCTC
           11168) >gi|6967666|emb|CAB72656.1| (AL139074) putative
           iron-uptake ABC transport system ATP-binding protein
           [Campylobacter jejuni]
           Length = 302
           
 Score = 73.7 bits (178), Expect = 6e-12
 Identities = 63/211 (29%), Positives = 107/211 (49%), Gaps = 16/211 (7%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           EI++L K FG      +   L N+N  +  GE ++++G SG+GK+TLLR+I    K    
Sbjct: 4   EIKNLSKNFG------KIQALENINLHVKEGEFLSILGGSGSGKSTLLRIIA---KLEQA 54

Query: 478 EKYRPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLNRAGLSD 537
             Y   S K EV    +   L P  +  E   + IL  +Y K +D N  +  L +    +
Sbjct: 55  SSYDLFSCKGEVALMFQNYALFP-HLNVE---KNILFALYDK-KDKNQILNHLLKTFEIE 109

Query: 538 AVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREA 597
            + Y+ K  E+S GQ +R   A  +A    +LL+DE  ++LD      + R++ +++   
Sbjct: 110 DLRYK-KIDEISGGQAQRVAFARAMARGCKLLLLDEPFSNLDQNLKQDLRRELKKMIENQ 168

Query: 598 GITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
           GITA+++TH  E    +  D++ F+  G ++
Sbjct: 169 GITAIMVTHDIEDAYCMS-DQIAFLEKGKIL 198


>pir||G81168 amino acid ABC transporter, ATP-binding protein NMB0696 [imported]
           - Neisseria meningitidis (group B strain MD58)
           >gi|7225924|gb|AAF41113.1| (AE002424) amino acid ABC
           transporter, ATP-binding protein [Neisseria meningitidis
           MC58]
           Length = 242
           
 Score = 73.7 bits (178), Expect = 6e-12
 Identities = 68/207 (32%), Positives = 106/207 (50%), Gaps = 22/207 (10%)

Query: 437 VLRNLNFTINPGEVVAVVGASGAGKTTLLRLI--LGAIKG--YWEEKYRPTSGKIEVPK- 491
           V+  +N  I  GEVV V G SG+GK+TL+R +  L +I+    W +       K ++ K 
Sbjct: 16  VINGVNLEIKKGEVVVVCGPSGSGKSTLIRTVNQLESIESGEIWVDGVNVADPKTDLNKI 75

Query: 492 NAKVSVLIPG-EIEPEFGSETILEHVY---RKIRDLNA------AVEVLNRAGLSDAVLY 541
             +V  +  G  + P     T+LE++     K++  NA      A+E+L R GL  A   
Sbjct: 76  REEVGFVFQGFNLYPHL---TVLENITLAPMKVKGQNAEQAEKKAMELLERVGL--AHKK 130

Query: 542 RAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITA 601
            A  S+LS GQ++R  IA  LA  P V+L DE  + LD      V  KV + + E+G+T 
Sbjct: 131 DAFPSQLSGGQQQRVAIARGLAMEPRVMLFDEPTSALDPEMVGEVL-KVMKDLAESGMTM 189

Query: 602 VIITHRPEVVKALDPDKVLFVGYGTVI 628
           + +TH     + +  D+V+FV  G ++
Sbjct: 190 MCVTHEMGFAREV-ADRVIFVDKGQIL 215


>gb|AAF71763.1|AF263912_2 (AF263912) NysG [Streptomyces noursei]
           Length = 605
           
 Score = 73.7 bits (178), Expect = 6e-12
 Identities = 57/213 (26%), Positives = 99/213 (45%), Gaps = 33/213 (15%)

Query: 436 PVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKV 495
           P++ NL+ T+ PG  VA+VG +GAGKTTL  L++          Y P SG+I +      
Sbjct: 373 PLIENLSLTVEPGSTVAIVGPTGAGKTTLGNLLM--------RFYEPDSGRI-LLDGTDT 423

Query: 496 SVLIPGEIEPEFG---------SETILEHV-YRKIRDLNAAVEVLNRAGLSDAVLYRA-- 543
           + +   ++   FG           TI E++ Y       A +E   RA  +D  +     
Sbjct: 424 ATMTRDDLRSRFGLVLQDTWLFGGTIAENIAYGAPGACRADIEEAARATCADRFIRTLPQ 483

Query: 544 --------KFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVR 595
                   +   +S G+K+   +A     RP VL++DE  + +DT T + + R ++ +  
Sbjct: 484 GYDTVLDDESGTVSAGEKQLLTVARAFLARPAVLVLDEATSSVDTRTEVLIQRAMNSL-- 541

Query: 596 EAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
            AG T+ +I HR   ++  D D ++ +  G ++
Sbjct: 542 RAGRTSFVIAHRLSTIR--DADLIVVMDAGRIV 572


>gb|AAD43626.1|AF071411_1 (AF071411) multidrug resistance protein MDR [Aspergillus nidulans]
            >gi|6856159|gb|AAF29805.1|AF173826_1 (AF173826)
            ABC-transporter [Aspergillus nidulans]
            Length = 1348
            
 Score = 73.4 bits (177), Expect = 7e-12
 Identities = 77/282 (27%), Positives = 117/282 (41%), Gaps = 62/282 (21%)

Query: 378  PKEPLWKPSYGKVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRPV 437
            P+   W     K+E +EG I F+NV   + +  +                       +PV
Sbjct: 1084 PQIDNWSEEGEKLETVEGEIEFRNVHFRYPTRPE-----------------------QPV 1120

Query: 438  LRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPK------ 491
            LR L+ T+ PG+ VA+VG SG GK+T + L+        E  Y   +G I V        
Sbjct: 1121 LRGLDLTVKPGQYVALVGPSGCGKSTTIALL--------ERFYDAIAGSILVDGKDISKL 1172

Query: 492  --NAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLNRAGLSDAVLY-------- 541
              N+  S L     EP     TI E++   I + +   E L +A   DA +Y        
Sbjct: 1173 NINSYRSFLSLVSQEPTLYQGTIKENILLGIVEDDVPEEFLIKA-CKDANIYDFIMSLPE 1231

Query: 542  ------RAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVR 595
                   +K   LS GQK+R  IA  L   P +LL+DE  + LD+ +   V   +    R
Sbjct: 1232 GFNTVVGSKGGMLSGGQKQRVAIARALLRDPKILLLDEATSALDSESEKVVQAALDAAAR 1291

Query: 596  EAGITAVIITHR------PEVVKALDPDKVLFVGYGTVIVRK 631
              G T + + HR       +V+   D  K++  G  + +V+K
Sbjct: 1292 --GRTTIAVAHRLSTIQKADVIYVFDQGKIVESGTHSELVQK 1331


>pir||T46950 probable ATPase component of 2-aminoethylphosphonate transporter
           phnT [imported] - Salmonella typhimurium
           >gi|1763082|gb|AAB39645.1| (U69493) PhnT [Salmonella
           typhimurium]
           Length = 369
           
 Score = 73.4 bits (177), Expect = 7e-12
 Identities = 62/209 (29%), Positives = 101/209 (47%), Gaps = 29/209 (13%)

Query: 437 VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVP------ 490
           VL+ L+ TI PGEV+A++G SG+GKTT+LR + G +        +P  G+I +       
Sbjct: 33  VLKPLSLTIEPGEVLALIGPSGSGKTTVLRAVAGFV--------QPAGGRILIGDTDVTH 84

Query: 491 ----KNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAV-----EVLNRAGLSDAVLY 541
               K     V+    + P    E  +    R  +   A +     + L   G+SD   Y
Sbjct: 85  LPPYKRGLAMVVQNYALFPHLKVEDNVAFGLRAQKQPKALINERVTQALKTVGMSD---Y 141

Query: 542 RAKF-SELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVRE-AGI 599
            A++  +LS GQ++R  IA  +A RP VLL+DE  + LD      +  +++ + RE   +
Sbjct: 142 AARYPHQLSGGQQQRVAIARAIAVRPRVLLLDEPLSALDAQIRHNMVEEIARLHRELPEL 201

Query: 600 TAVIITHRPEVVKALDPDKVLFVGYGTVI 628
           T + +TH       L  DK+  +  G++I
Sbjct: 202 TILYVTHDQTEALTL-ADKIGIMKDGSLI 229


>pir||T45311 cell division atp-binding protein [imported] - Mycobacterium leprae
           >gi|2326691|emb|CAB11002.1| (Z98271) cell division
           atp-binding protein [Mycobacterium leprae]
           Length = 229
           
 Score = 73.4 bits (177), Expect = 7e-12
 Identities = 65/206 (31%), Positives = 99/206 (47%), Gaps = 31/206 (15%)

Query: 429 RHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIE 488
           +++ + RP L N+N  I+ GE V ++G SG+GK+T +RL+LGA          PTSG + 
Sbjct: 10  KYKSLARPALDNVNVKIDKGEFVFLIGPSGSGKSTFMRLLLGA--------ETPTSGDVR 61

Query: 489 VPK---NAKVSVLIP------GEIEPEF---GSETILEHVY-------RKIRDLNAAV-E 528
           V K   N      IP      G +  +F     +T+ E+V        R+   +N  V +
Sbjct: 62  VSKFHVNKLPGRHIPRLRQVIGCVFQDFRLLQQKTVYENVAFALEVIGRRSDAINQVVPD 121

Query: 529 VLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVAR 588
           VL   GLS          ELS G+++R  IA     RP VLL DE   +LD  T+  +  
Sbjct: 122 VLETVGLSGKA--NRLPDELSGGEQQRVAIARAFVNRPLVLLADEPTGNLDPDTSKDI-M 178

Query: 589 KVSEIVREAGITAVIITHRPEVVKAL 614
            + E +   G T ++ TH   +V ++
Sbjct: 179 DLLERINRTGTTVLMATHDHHIVDSM 204


>pir||D69627 cell-division ATP-binding protein ftsE - Bacillus subtilis
           >gi|2618833|gb|AAC67262.1| (AF017113) cell division
           ATP-binding protein [Bacillus subtilis]
           >gi|2636052|emb|CAB15543.1| (Z99122) cell-division
           ATP-binding protein [Bacillus subtilis]
           Length = 228
           
 Score = 73.4 bits (177), Expect = 7e-12
 Identities = 67/234 (28%), Positives = 114/234 (48%), Gaps = 43/234 (18%)

Query: 418 EIQDLLKAF--GVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGY 475
           E++++ KA+  GV+        L  ++ TI+PGE V VVG SGAGK+T +++I      Y
Sbjct: 3   EMKEVYKAYPNGVK-------ALNGISVTIHPGEFVYVVGPSGAGKSTFIKMI------Y 49

Query: 476 WEEKYRPTSGKI-------------EVP-KNAKVSVLIPG-EIEPEFGSETILEHVYRKI 520
            EEK  PT G+I             E+P    K+ V+    ++ P+    T+ E+V   +
Sbjct: 50  REEK--PTKGQILINHKDLATIKEKEIPFVRRKIGVVFQDFKLLPKL---TVFENVAFAL 104

Query: 521 RDLNAAVEVLNRAGLSDAVLYRAKF------SELSTGQKERAKIASLLAERPNVLLIDEF 574
             +     V+ +  L    L + K        +LS G+++R  IA  +   P+V++ DE 
Sbjct: 105 EVIGEQPSVIKKRVLEVLDLVQLKHKARQFPDQLSGGEQQRVSIARSIVNNPDVVIADEP 164

Query: 575 AAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
             +LD  T+  V + + EI    G T V+ TH  E+V  +   +V+ +  G ++
Sbjct: 165 TGNLDPDTSWEVMKTLEEI-NNRGTTVVMATHNKEIVNTM-KKRVIAIEDGIIV 216


>gb|AAB88659.1| (U62935) multidrug resistance protein 2 [Aspergillus fumigatus]
           >gi|2673957|gb|AAB88660.1| (U62936) multidrug resistance
           protein 2 [Aspergillus fumigatus]
           Length = 791
           
 Score = 73.4 bits (177), Expect = 7e-12
 Identities = 72/262 (27%), Positives = 115/262 (43%), Gaps = 53/262 (20%)

Query: 379 KEPLWKPSYG-KVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRPV 437
           ++P   P+ G KV    GPI F+NVT  + +   +                       P+
Sbjct: 485 RQPTISPTKGEKVASARGPIRFENVTFSYPTRPAV-----------------------PI 521

Query: 438 LRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEV-------- 489
            R+LNF I  G  VA+VG SG GK+T+  ++L          Y PT G++ +        
Sbjct: 522 FRDLNFEIPQGTNVAIVGPSGGGKSTIASILL--------RFYSPTEGRVLIGGKDITHM 573

Query: 490 -PKNAKVSVLIPGEIEPEFGSETILEHV-----YRKIRDLNAAVEVLNRAGLSD-----A 538
             K+ +  + I  + EP   S TI E++       K  ++ AA    N   +SD      
Sbjct: 574 NAKSLRRKIGIVSQ-EPVLFSGTIAENIAYGKPQAKRSEIVAAARKANCQFISDFPDGLD 632

Query: 539 VLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAG 598
                + ++LS GQK+R  IA  L + P++L++DE  + LD  +   V   ++ ++R   
Sbjct: 633 TQVGPRGAQLSGGQKQRIAIARALIKDPDILILDEATSALDAESETLVNSALTALLR-GN 691

Query: 599 ITAVIITHRPEVVKALDPDKVL 620
            T + I HR   +K  D   VL
Sbjct: 692 NTTISIAHRLSTIKRSDTIIVL 713


>pir||T40790 probable permease - fission yeast (Schizosaccharomyces pombe)
           >gi|4760347|emb|CAB42370.1| (AL049769) putative permease
           [Schizosaccharomyces pombe]
           Length = 726
           
 Score = 73.4 bits (177), Expect = 7e-12
 Identities = 62/215 (28%), Positives = 100/215 (45%), Gaps = 30/215 (13%)

Query: 437 VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVS 496
           +  NL+F I+PG  VA+V  SG GK+T+ +L+L          Y P+SGKI +     +S
Sbjct: 499 IFDNLSFDIHPGTNVAIVAPSGGGKSTISQLLL--------RFYAPSSGKI-LADGVDIS 549

Query: 497 VLIPGEIEPEFG---------SETILEHV-YRKIRDLNAAVE-VLNRAGLSDAVLYRAKF 545
                +    FG         S TI E++ Y K       +E    RA  S  + +  K+
Sbjct: 550 TYNVHQWRSHFGLVGQEPVLFSGTIGENIAYGKSNASQEEIEDAAKRANCSFVLSFPEKW 609

Query: 546 S--------ELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREA 597
           S        +LS GQK+R  IA  L   P  L++DE  + LD    + V + +  ++   
Sbjct: 610 STQVGTRGLQLSGGQKQRIAIARALLRNPAFLILDEATSALDGEAEVMVDKTIQSLMHNR 669

Query: 598 GITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKS 632
            +T + I H+   ++    D+++ VG G V+ + S
Sbjct: 670 SMTTITIAHKLATIRR--ADQIIVVGDGKVLEQGS 702


>emb|CAB59828.1| (AJ012388) hypothetical protein [Lactococcus lactis]
           Length = 368
           
 Score = 73.4 bits (177), Expect = 7e-12
 Identities = 68/250 (27%), Positives = 111/250 (44%), Gaps = 45/250 (18%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E+ +L   F  + R++    ++N    I  G++  V+G SGAGK+TL+R I         
Sbjct: 6   ELNNLSVQFHQKGRLVT--AVKNATLHIEKGDIYGVIGYSGAGKSTLVRTI--------N 55

Query: 478 EKYRPTSGKIEVPK----NAKVSVLIPGEIEPEF--------------GSETILEHV--- 516
              +PT G+I +      +++  V   G    EF                +T+  +V   
Sbjct: 56  LLQKPTEGQIVINGEKIFDSENPVKFTGAKLREFRQKIGMIFQHFNLLSEKTVFNNVAFA 115

Query: 517 --YRKIRDLNAAVEVLNRAGLSDAVLYRAKF-----------SELSTGQKERAKIASLLA 563
             + +I D N     L +   +D V    K            ++LS GQK+R  IA  LA
Sbjct: 116 LQHSQIEDKNGKKRYLTKKEKNDKVTELLKLVDLADLSDKYPAQLSGGQKQRVAIARALA 175

Query: 564 ERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVG 623
             P +L+ DE  + LD  T  ++   +  +  + GIT V+ITH  +VVK +  +KV  + 
Sbjct: 176 NDPEILISDEGTSALDPKTTNQILDLLKSLHEKLGITVVLITHEMQVVKEI-ANKVAVMQ 234

Query: 624 YGTVIVRKSL 633
            G +I + SL
Sbjct: 235 NGEIIEQNSL 244


>gb|AAF51223.1| (AE003582) CG9892 gene product [Drosophila melanogaster]
           Length = 615
           
 Score = 73.4 bits (177), Expect = 7e-12
 Identities = 62/209 (29%), Positives = 99/209 (46%), Gaps = 21/209 (10%)

Query: 411 DIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILG 470
           ++ G+    +DL+    V  +  ++ VL+ +  T   GE+ A++G SGAGK++L+ ++ G
Sbjct: 9   NVYGIDIHFEDLVYQVNVPKKPEKKSVLKGIKGTFKSGELTAIMGPSGAGKSSLMNILTG 68

Query: 471 AIKGYWEEKYRPTSGKIEVPKNAKVS--VLIPGEIEPEFG-SETILEHVYRKIRDLNAAV 527
             K          SGKIE+ K  K+   ++      P F   ET+L     KI   N  V
Sbjct: 69  LTKS-------GVSGKIEIGKARKLCGYIMQDDHFFPYFTVEETMLMAATLKIS--NQCV 119

Query: 528 EVLNRAGLSDAVL--------YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLD 579
            +  +  L D +L         + K S LS GQK+R  IA  L + P VL +DE    LD
Sbjct: 120 SLKEKRTLIDYLLNSLKLTKTRQTKCSNLSGGQKKRLSIALELIDNPAVLFLDEPTTGLD 179

Query: 580 TLTAMRVARKVSEIVREAGITAVIITHRP 608
           + ++    + +  +  E G T V   H+P
Sbjct: 180 SSSSFDTIQLLRGLANE-GRTIVCTIHQP 207


>dbj|BAB05182.1| (AP001512) ABC transporter (ATP-binding protein) [Bacillus
           halodurans]
           Length = 240
           
 Score = 73.4 bits (177), Expect = 7e-12
 Identities = 68/220 (30%), Positives = 102/220 (45%), Gaps = 18/220 (8%)

Query: 419 IQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLR---LILGAIKGY 475
           ++DL K+FG         VL+ +   I  G+VVAV+G SG+GK+T LR   L+     G+
Sbjct: 4   VKDLHKSFG------SLEVLKGITTEIQKGDVVAVIGPSGSGKSTFLRCLNLLEVPTSGH 57

Query: 476 -WEEKYRPTSGKIEVPK-NAKVSVLIPG-EIEPEFGSETILEHVYRKIRDLNAAVEVLNR 532
            W +    T  K  V K   K+ ++     + P       L     K++ ++ A  +   
Sbjct: 58  VWIDDEEITHPKTNVGKLRTKIGMVFQHFHLFPHMTVMENLTFAPMKVKGVSKAEAIAKG 117

Query: 533 AGLSDAVLYRAKFSE----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVAR 588
             L   V    K  E    LS GQK+R  IA  LA  P V+L DE  + LD      V  
Sbjct: 118 ESLLQKVGLLEKRDEYPSRLSGGQKQRVAIARALAMDPEVMLFDEPTSALDPEMVKEVLA 177

Query: 589 KVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
            + ++  E G+T VI+TH     K +  D+VLF+  G ++
Sbjct: 178 VMKDLA-ETGMTMVIVTHEMGFAKEV-ADRVLFLDQGILL 215


>dbj|BAB07321.1| (AP001519) cell-division ATP-binding protein [Bacillus halodurans]
           Length = 223
           
 Score = 73.4 bits (177), Expect = 7e-12
 Identities = 67/222 (30%), Positives = 111/222 (49%), Gaps = 31/222 (13%)

Query: 426 FGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSG 485
           FG   R + + ++ ++   I  GE V +VG SGAGK+T +++I      Y EE  RPT G
Sbjct: 2   FGRLIRTVLKRLMESI-LNIEKGEFVYIVGPSGAGKSTFIKMI------YREE--RPTKG 52

Query: 486 KIEVPKNAKVSVL----IP------GEIEPEFG---SETILEHVYRKIRDLNAAVEVLNR 532
           +I +  N  +S L    IP      G +  +F    S+++ E+V   +  +  + E + +
Sbjct: 53  EIVI-NNTNLSSLKERQIPYLRRNIGVVFQDFKLLTSQSVYENVAFALEVIEESPEAIKK 111

Query: 533 AGLSDAVLYRAKF------SELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRV 586
             +    + R K       SELS G+++R  IA  +  +P+VL+ DE   +LD  TA  +
Sbjct: 112 KVMDVLDIVRLKNKARFLPSELSGGEQQRVAIARAIVNQPDVLIADEPTGNLDPDTAWGI 171

Query: 587 ARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
              + EI R  G T V+ TH  E+V  +   +V+ +  G V+
Sbjct: 172 MDTLEEINR-LGTTVVMATHNKEIVNTI-KRRVIAIENGRVV 211


>gi|10955056 occP [Agrobacterium tumefaciens] >gi|464298|sp|P35117|OCCP_AGRTU
           OCTOPINE PERMEASE ATP-BINDING PROTEIN P
           >gi|95106|pir||C41044 octopine transport protein occP -
           Agrobacterium tumefaciens plasmid pTiA6 and pTiB6S3
           >gi|154771|gb|AAA98381.1| (AF242881) occP [Agrobacterium
           tumefaciens] >gi|496543|emb|CAA82985.1| (Z30328) OccP
           [Agrobacterium tumefaciens]
           Length = 262
           
 Score = 73.0 bits (176), Expect = 1e-11
 Identities = 69/233 (29%), Positives = 116/233 (49%), Gaps = 33/233 (14%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLI-------LG 470
           +++D+ K FG         VL  ++ + N GEV++++G+SG+GK+TLLR +        G
Sbjct: 10  QLKDIRKNFG------NLEVLHGVSLSANEGEVISILGSSGSGKSTLLRCVNMLEVPNAG 63

Query: 471 AIKGYWEE-KYRPTSGKIEVPKNAKVSVLIPGEIEPEF------GSETILEH-----VYR 518
           ++    EE      +G++  PK+ K    +       F        +TIL++     V+ 
Sbjct: 64  SVAIMGEEIALEHRAGRLARPKDLKQVNRLRERAAMVFQGFNLWSHQTILQNVMEAPVHV 123

Query: 519 KIRDLNA----AVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEF 574
           + RD  A    A  +L R G+  A    A  SELS GQ++RA IA  LA RP+V+L DE 
Sbjct: 124 QGRDRKACRDEAEALLERVGI--ASKRDAYPSELSGGQQQRAAIARALAMRPDVMLFDEP 181

Query: 575 AAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTV 627
            + LD      V + + ++  E G T +I+TH  +  + +   + +F+  G +
Sbjct: 182 TSALDPELVGEVLKVMRDLAAE-GRTMLIVTHEMDFARDVS-SRTVFLHQGVI 232


>pir||T30293 ABC transport protein homolog - Salmonella typhi
            >gi|1698599|gb|AAB37256.1| (U62129) ATP binding cassette
            (ABC) transporter homolog [Salmonella typhi]
            Length = 1218
            
 Score = 73.0 bits (176), Expect = 1e-11
 Identities = 66/228 (28%), Positives = 104/228 (44%), Gaps = 33/228 (14%)

Query: 423  LKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRP 482
            L+A   R+    +PVL NL+ TI PG VVAVVG SGAGK+TL++L+ G         Y P
Sbjct: 969  LEALTFRYPEKTQPVLDNLSLTIPPGTVVAVVGRSGAGKSTLIKLLAGL--------YSP 1020

Query: 483  TSGKIEVPKNAKVSVLIPGEIEPEFG---------SETILEHV-YRKIRDLNAAVEVLNR 532
             SG+I V +   +      +   + G         S  I E++ Y +    +  VE+  R
Sbjct: 1021 GSGQIRVGERL-IDAASLSDYRRQTGLVTQDVALFSGDIAENIRYSRPDSSDTEVEIAAR 1079

Query: 533  -AGLSDAVLY---------RAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLT 582
             AGL + V +             ++LS GQ++   +A     + ++LL+DE  A +D   
Sbjct: 1080 QAGLFETVQHLPLGFRTPVNNGGTDLSAGQRQLIALARAQLAQAHILLLDEATARIDRSA 1139

Query: 583  AMRVARKVSEIVREAGITAVIITHRPEVVKALDP----DKVLFVGYGT 626
              R+   ++ +       A+I+ HR    +  D     DK     YG+
Sbjct: 1140 EERLITSLTGVTHTEKRIALIVAHRLTTARRCDVIVVIDKGCIAEYGS 1187


>sp|P75831|YBJZ_ECOLI HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN YBJZ
           >gi|7430353|pir||G64826 probable ABC transporter ybjZ -
           Escherichia coli >gi|1787105|gb|AAC73966.1| (AE000189)
           putative ATP-binding component of a transport system
           [Escherichia coli K12] >gi|4062463|dbj|BAA35598.1|
           (D90725) ABC transporter probable ATP-binding subunit
           homolog [Escherichia coli]
           Length = 648
           
 Score = 73.0 bits (176), Expect = 1e-11
 Identities = 67/226 (29%), Positives = 109/226 (47%), Gaps = 24/226 (10%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E++D+ +++      ++  VL+ ++  I  GE+VA+VGASG+GK+TL+  ILG +     
Sbjct: 6   ELKDIRRSYPAGDEQVE--VLKGISLDIYAGEMVAIVGASGSGKSTLMN-ILGCLDKATS 62

Query: 478 EKYRPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEH-----------VY----RKIRD 522
             YR     +       ++ L        F    +L H           VY    RK R 
Sbjct: 63  GTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLTAEQNVEVPAVYAGLERKQRL 122

Query: 523 LNAAVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLT 582
           L A  E+L R GL D   Y    ++LS GQ++R  IA  L     V+L DE    LD+ +
Sbjct: 123 LRAQ-ELLQRLGLEDRTEYYP--AQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHS 179

Query: 583 AMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
              V   + ++ R+ G T +I+TH P+V  A   ++V+ +  G ++
Sbjct: 180 GEEVMAILHQL-RDRGHTVIIVTHDPQV--AAQAERVIEIRDGEIV 222


>gi|11038656 ATP-binding cassette, sub-family B, member 11; bile salt export
           pump [Mus musculus] >gi|6502606|gb|AAF14372.1|AF133903_1
           (AF133903) liver bile salt export pump;
           sister-of-p-glycoprotein [Mus musculus domesticus]
           Length = 1321
           
 Score = 73.0 bits (176), Expect = 1e-11
 Identities = 69/262 (26%), Positives = 115/262 (43%), Gaps = 56/262 (21%)

Query: 389 KVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPG 448
           K++ ++G I F NVT  + S  ++K                       +L NL+  I PG
Sbjct: 412 KLDRIKGEIEFHNVTFHYPSRPEVK-----------------------ILNNLSMVIKPG 448

Query: 449 EVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVSVLIPG------- 501
           E  A VG+SGAGK+T L+LI        +  Y P  G + +  +   S+ I         
Sbjct: 449 ETTAFVGSSGAGKSTALQLI--------QRFYDPCEGMVTLDGHDIRSLNIRWLRDQIGI 500

Query: 502 -EIEPEFGSETI------------LEHVYRKIRDLNAAVEVLNRAGLSDAVLYRAKFSEL 548
            E EP   S TI            +E + +  +D NA   ++      D ++      ++
Sbjct: 501 VEQEPVLFSTTIAENIRLGREEATMEDIVQAAKDANAYNFIMALPQQFDTLVGEGG-GQM 559

Query: 549 STGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRP 608
           S GQK+R  IA  L  +P +LL+D   + LD  +  +V   +++I  + G T + + HR 
Sbjct: 560 SGGQKQRVAIARALIRKPKILLLDMATSALDNESEAKVQGALNKI--QHGHTIISVAHRL 617

Query: 609 EVVKALDPDKVLFVGYGTVIVR 630
             V++   D ++   +GT + R
Sbjct: 618 STVRS--ADVIIGFEHGTAVER 637


>pir||E81105 ABC transporter, ATP-binding protein NMB1240 [imported] - Neisseria
           meningitidis (group B strain MD58)
           >gi|7226480|gb|AAF41621.1| (AE002472) ABC transporter,
           ATP-binding protein [Neisseria meningitidis MC58]
           Length = 542
           
 Score = 73.0 bits (176), Expect = 1e-11
 Identities = 74/276 (26%), Positives = 124/276 (44%), Gaps = 26/276 (9%)

Query: 361 QEAKEYLERYFKEDPYAPKEP--LWKPSYGKVEMLE-GPIVFKNVTKVFESELDIKGLPQ 417
           QE +E++ R+      A +    L +    K EM+E  P   +N    FE++   K   Q
Sbjct: 263 QELQEFVARFSANKSKARQATSRLKQADKIKSEMVEVKPSTRQNPYIRFEADEKAKLHRQ 322

Query: 418 --EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGY 475
             E++ L K F       +  + +NLNF +  G+ +A++G +GAGK+TLL+L+ GA    
Sbjct: 323 AVEVEKLAKRF-------ETQLFKNLNFILEAGQRLAIIGPNGAGKSTLLKLLAGAYNPE 375

Query: 476 WEEKYRPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLNRA-- 533
           + +   P  G I+  + A V    P + E +F  +  L    R+        +V+     
Sbjct: 376 YSDGLLPDEGTIKWAEKASVG-YYPQDHENDFDVDMDLSEWMRQWGQEGDDEQVIRGTLG 434

Query: 534 ----GLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARK 589
               G +D V    K   LS G+K R     LL  +PNVL++DE   H+D    M     
Sbjct: 435 RLLFGSNDVV---KKVKVLSGGEKGRMLYGKLLLLKPNVLVMDEPTNHMD----MESIES 487

Query: 590 VSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYG 625
           ++  + +   T + ++H  + V +L    +   G G
Sbjct: 488 LNMALEKYNGTLIFVSHDRQFVSSLATQIIELDGKG 523


>pir||B81910 probable ABC-transporter ATP-binding protein NMA1409 [imported] -
           Neisseria meningitidis (group A strain Z2491)
           >gi|7380068|emb|CAB84649.1| (AL162755) putative
           ABC-transporter ATP-binding protein [Neisseria
           meningitidis Z2491]
           Length = 542
           
 Score = 73.0 bits (176), Expect = 1e-11
 Identities = 74/276 (26%), Positives = 124/276 (44%), Gaps = 26/276 (9%)

Query: 361 QEAKEYLERYFKEDPYAPKEP--LWKPSYGKVEMLE-GPIVFKNVTKVFESELDIKGLPQ 417
           QE +E++ R+      A +    L +    K EM+E  P   +N    FE++   K   Q
Sbjct: 263 QELQEFVARFSANKSKARQATSRLKQADKIKSEMVEVKPSTRQNPYIRFEADEKAKLHRQ 322

Query: 418 --EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGY 475
             E++ L K F       +  + +NLNF +  G+ +A++G +GAGK+TLL+L+ GA    
Sbjct: 323 AVEVEKLAKRF-------ETQLFKNLNFILEAGQRLAIIGPNGAGKSTLLKLLAGAYNPE 375

Query: 476 WEEKYRPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLNRA-- 533
           + +   P  G I+  + A V    P + E +F  +  L    R+        +V+     
Sbjct: 376 YSDGLLPDEGSIKWAEKASVG-YYPQDHENDFDVDMDLSEWMRQWGQDGDDEQVIRGTLG 434

Query: 534 ----GLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARK 589
               G +D V    K   LS G+K R     LL  +PNVL++DE   H+D    M     
Sbjct: 435 RLLFGSNDVV---KKVKVLSGGEKGRMLYGKLLLLKPNVLVMDEPTNHMD----MESIES 487

Query: 590 VSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYG 625
           ++  + +   T + ++H  + V +L    +   G G
Sbjct: 488 LNMALEKYNGTLIFVSHDRQFVSSLATQIIELDGKG 523


>gb|AAF69534.1|AC008007_9 (AC008007) F12M16.17 [Arabidopsis thaliana]
           Length = 590
           
 Score = 73.0 bits (176), Expect = 1e-11
 Identities = 59/217 (27%), Positives = 106/217 (48%), Gaps = 22/217 (10%)

Query: 434 QRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIK-----GYWEEKYRPTSGKIE 488
           ++ +L++++      E+ A+ G SGAGKTTLL ++ G +      G      RP  G   
Sbjct: 47  EKVILKDVSCDARSAEITAIAGPSGAGKTTLLEILAGKVSHGKVSGQVLVNGRPMDG--- 103

Query: 489 VPKNAKVSVLIPGEIEPEFGSETILE--------HVYRKIRDLNAAVE-VLNRAGL---S 536
            P+  +VS  +P E +  F   T+ E         +  K +D  A V+ ++   GL   +
Sbjct: 104 -PEYRRVSGFVPQE-DALFPFLTVQETLTYSALLRLKTKRKDAAAKVKRLIQELGLEHVA 161

Query: 537 DAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVRE 596
           D+ + +   S +S G++ R  I   L   PNV+LIDE  + LD+ +A++V   + ++  +
Sbjct: 162 DSRIGQGSRSGISGGERRRVSIGVELVHDPNVILIDEPTSGLDSASALQVVTLLKDMTIK 221

Query: 597 AGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
            G T V+  H+P        D+++ +  G V+   S+
Sbjct: 222 QGKTIVLTIHQPGFRILEQIDRIVLLSNGMVVQNGSV 258


>prf||1901178A cystic fibrosis transmembrane conductance regulator [Rattus
           norvegicus]
           Length = 1478
           
 Score = 72.6 bits (175), Expect = 1e-11
 Identities = 60/209 (28%), Positives = 107/209 (50%), Gaps = 14/209 (6%)

Query: 432 VIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPK 491
           ++  PVL+N+N  I  GE++A+ G++GAGKT+LL LILG ++    E     SG++    
Sbjct: 435 LVGNPVLKNINLNIKKGEMLAITGSTGAGKTSLLMLILGELEA--SEGIIKHSGRVSF-- 490

Query: 492 NAKVSVLIPGEIEPE--FGSETILEHVYRKIRDLNAAVEVLNRAGLSDAVLYRAKFSELS 549
           ++ +S ++PG I+    FG  +  E+ Y+ +       E + +    D  +       LS
Sbjct: 491 SSLISWIMPGTIKENIIFG-VSYDEYRYKSVVKACQLQEDMTKFAEQDNTVLGEGGVTLS 549

Query: 550 TGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARK-VSEIVREAGITAVIITHRP 608
            GQ+ R  +A  + +  ++ L+D    +LD LT  ++    V +++  A  T +++T + 
Sbjct: 550 GGQRARISLARAVYKDADLYLLDSPFGYLDVLTEEQIFESCVCKLM--ASKTRILVTSKM 607

Query: 609 EVVKALDPDKVLFVG----YGTVIVRKSL 633
           E +K  D   +L  G    YGT    +SL
Sbjct: 608 EQLKKADKILILHEGSSYFYGTFSELQSL 636


>pir||I76773 ATP binding component of ABC-transporter - Escherichia coli
           >gi|598468|dbj|BAA07748.1| (D43637) putative ATP binding
           component of ABC-transporter [Escherichia coli]
           Length = 431
           
 Score = 72.6 bits (175), Expect = 1e-11
 Identities = 59/218 (27%), Positives = 107/218 (49%), Gaps = 27/218 (12%)

Query: 419 IQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEE 478
           I+ LL     RH   ++ VL+++NF+I PGE V +VG +GAGK+TLL+L+ G        
Sbjct: 23  IEKLLPGDKPRHS--KKWVLKDINFSIEPGEAVGIVGVNGAGKSTLLKLLTGTT------ 74

Query: 479 KYRPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLNR------ 532
             +PT G IE+       + +     P+F   T  ++VY     +    E + R      
Sbjct: 75  --QPTKGSIEIQGRVAALLELGMGFHPDF---TGRQNVYMSGLMMGLGREEIERLMPEIE 129

Query: 533 --AGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKV 590
             A + D +    +    S+G + R   A   A RP++L++DE  +  D+    +   ++
Sbjct: 130 AFADIGDYIEEPVRI--YSSGMQMRLAFAVATASRPDILIVDEALSVGDSRFQAKCYARI 187

Query: 591 SEIVREAGITAVIITHRP-EVVKALDPDKVLFVGYGTV 627
           ++  +E G T ++++H   ++VK    D+ +F+  G +
Sbjct: 188 ADF-KEQGTTLLLVSHSAGDIVKHC--DRAIFLKNGDI 222


>dbj|BAA28332.1| (AB010293) ATP binding component of ABC-transporter [Escherichia
           coli]
           Length = 431
           
 Score = 72.6 bits (175), Expect = 1e-11
 Identities = 59/218 (27%), Positives = 107/218 (49%), Gaps = 27/218 (12%)

Query: 419 IQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEE 478
           I+ LL     RH   ++ VL+++NF+I PGE V +VG +GAGK+TLL+L+ G        
Sbjct: 23  IEKLLPGDKPRHS--KKWVLKDINFSIEPGEAVGIVGVNGAGKSTLLKLLTGTT------ 74

Query: 479 KYRPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLNR------ 532
             +PT G IE+       + +     P+F   T  ++VY     +    E + R      
Sbjct: 75  --QPTKGSIEIQGRVAALLELGMGFHPDF---TGRQNVYMSGLMMGLGREEIERLMPEIE 129

Query: 533 --AGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKV 590
             A + D +    +    S+G + R   A   A RP++L++DE  +  D+    +   ++
Sbjct: 130 AFADIGDYIEEPVRI--YSSGMQMRLAFAVATASRPDILIVDEALSVGDSRFQAKCYARI 187

Query: 591 SEIVREAGITAVIITHRP-EVVKALDPDKVLFVGYGTV 627
           ++  +E G T ++++H   ++VK    D+ +F+  G +
Sbjct: 188 ADF-KEQGTTLLLVSHSAGDIVKHC--DRAIFLKNGDI 222


>emb|CAC05880.1| (AL391754) putative ABC transporter ATP-binding protein
           [Streptomyces coelicolor]
           Length = 229
           
 Score = 72.6 bits (175), Expect = 1e-11
 Identities = 64/213 (30%), Positives = 95/213 (44%), Gaps = 17/213 (7%)

Query: 422 LLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAI---KGYWEE 478
           LL A  +R        L    F+I+PGEVVAV+G SG+GK+TLL  + G +    G    
Sbjct: 8   LLSADQLRKAYGPTLALDGAEFSIHPGEVVAVMGPSGSGKSTLLHCLAGIVPPDSGTITY 67

Query: 479 KYRPTSGKIEVPKNAKVS-----VLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVLNRA 533
             R  S   +  ++A        V   G++ PE    T +E+V   +R    + +   RA
Sbjct: 68  NGRELSAMSDAQRSALRRSDFGFVFQFGQLVPEL---TCVENVALPLRLNGTSRKEAERA 124

Query: 534 GLSDAV------LYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVA 587
            LS         L + +  E+S GQ +R  +A  L   P VL  DE    LD+L   RV 
Sbjct: 125 ALSWMERLEVDDLRKKRPGEVSGGQGQRVAVARSLVTNPRVLFADEPTGALDSLNGERVM 184

Query: 588 RKVSEIVREAGITAVIITHRPEVVKALDPDKVL 620
             +++  R      V++TH   V    D + V+
Sbjct: 185 ELLTDAARSTNAAVVLVTHEARVAAYSDREIVV 217


>gb|AAG26946.1|AC069471_7 (AC069471) P-glycoprotein, putative [Arabidopsis thaliana]
            Length = 1247
            
 Score = 72.6 bits (175), Expect = 1e-11
 Identities = 66/261 (25%), Positives = 122/261 (46%), Gaps = 56/261 (21%)

Query: 384  KPSYGKVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNF 443
            +P+   V  ++G I F+NV+  + +  +I                        + +NLN 
Sbjct: 993  QPNSRLVTHIKGDIEFRNVSFAYPTRPEIA-----------------------IFKNLNL 1029

Query: 444  TINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVSVLIPG-- 501
             ++ G+ +AVVG SG+GK+T++ LI+          Y P++G + +  +   SV +    
Sbjct: 1030 RVSAGKSLAVVGPSGSGKSTVIGLIM--------RFYDPSNGNLCIDGHDIKSVNLRSLR 1081

Query: 502  ------EIEPEFGSETILEHVYRKIRDLNAA-VEVLNRAGLSDAVLYRAKFSE------- 547
                  + EP   S +I E++  K  + NA+  E++  A  ++A  + ++  E       
Sbjct: 1082 KKLALVQQEPALFSTSIHENI--KYGNENASEAEIIEAAKAANAHEFISRMEEGYMTHVG 1139

Query: 548  -----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAV 602
                 LS GQK+R  IA  + + P+VLL+DE  + LDT    +V   + ++++  G T +
Sbjct: 1140 DKGVQLSGGQKQRVAIARAVLKDPSVLLLDEATSALDTSAEKQVQEALDKLMK--GRTTI 1197

Query: 603  IITHRPEVVKALDPDKVLFVG 623
            ++ HR   ++  D   VL  G
Sbjct: 1198 LVAHRLSTIRKADTIVVLHKG 1218


>pir||S30327 multidrug resistance protein 1 - Entamoeba histolytica
            >gi|158971|gb|AAA29112.1| (M88599) P-glycoprotein-1
            [Entamoeba histolytica]
            Length = 1302
            
 Score = 72.2 bits (174), Expect = 2e-11
 Identities = 59/215 (27%), Positives = 108/215 (49%), Gaps = 36/215 (16%)

Query: 437  VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVP----KN 492
            VL+ ++F    G+ +A+VGASG GK+T ++LI        E  Y PTSG++ +     K+
Sbjct: 1074 VLKGISFKAEQGKTIALVGASGCGKSTTIQLI--------ERFYDPTSGEVLLDGHNIKD 1125

Query: 493  AKVSVL-----IPGEIEPEFGSETILEHVYRKIRD--------LNAAVEVLNRAGLSDAV 539
              +  L     + G+ EP   +E++++++ R + +        + AA ++ N      A+
Sbjct: 1126 LNIHFLRNQIGLVGQ-EPVLFAESVIDNIKRGVPEGVEVSNEQIYAAAKMANAHDFISAM 1184

Query: 540  ------LYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEI 593
                  +   + S+LS GQK+R  IA  L   P VLL+DE  + LD+ +   V   + + 
Sbjct: 1185 PEGYNTMVGDRGSQLSGGQKQRIAIARALIRNPKVLLLDEATSALDSESEKIVQDALDKA 1244

Query: 594  VREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
             +  G T ++I HR   ++  + DK+  +  G ++
Sbjct: 1245 SK--GRTTIVIAHRLSTIQ--NADKIYVIMRGKIV 1275


>gb|AAA96713.1| (L42939) major histocompatibility complex class I [Mesocricetus
           auratus]
           Length = 703
           
 Score = 72.2 bits (174), Expect = 2e-11
 Identities = 65/236 (27%), Positives = 114/236 (47%), Gaps = 38/236 (16%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E QD+  ++  R     +PVL+ L FT++PG+V A+VG +G+GK+T+   +        +
Sbjct: 469 EFQDVTFSYPSRPX---KPVLKGLTFTLHPGKVTALVGPNGSGKSTVAAPL--------Q 517

Query: 478 EKYRPTSGKIEVPKNAKV---------SVLIPGEIEPEFGSETILEHVYRKIRDL-NAAV 527
             Y+PT G++ +     V          V++ G+ EP   S ++ +++   ++D  +A V
Sbjct: 518 NLYQPTGGQLLLDGQPLVQYDHHYLHRQVVLVGQ-EPVLFSGSVKDNIAYGLKDCEDAQV 576

Query: 528 EVLNRAGLSDAVL----------YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAH 577
               RA  +D  +             K S+L+ GQK+R  IA  L   P VL++DE  + 
Sbjct: 577 MAAVRAACADDFIGEMPDGIHTEIGEKGSQLAVGQKQRLAIARALVRNPRVLILDEATSA 636

Query: 578 LDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
           LD+     +    S+  R    T ++I HR   V+  + D+VL +  G ++    L
Sbjct: 637 LDSQCEQALQAWRSKGDR----TVLVIAHRLHTVQ--NVDQVLVLKQGQLVEHSQL 686


>gi|11498626 ABC transporter, ATP-binding protein [Archaeoglobus fulgidus]
           >gi|7445710|pir||E69377 ABC transporter, ATP-binding
           protein homolog - Archaeoglobus fulgidus
           >gi|2649574|gb|AAB90222.1| (AE001033) ABC transporter,
           ATP-binding protein [Archaeoglobus fulgidus]
           Length = 275
           
 Score = 72.2 bits (174), Expect = 2e-11
 Identities = 61/224 (27%), Positives = 109/224 (48%), Gaps = 29/224 (12%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E+++L K +G    V      + ++F++  GEV+ ++G +GAGK+T L+++ G I     
Sbjct: 3   EVRNLFKRYGSFEAV------KGISFSVRRGEVLGLIGENGAGKSTTLKILAGLI----- 51

Query: 478 EKYRPTSGKI-----EVPKNAKVSVLIPGEIEPEFGSETILEH--VYRKIRDLNAAVE-V 529
              RP  G++     +  +  K  +    EI+  + + T+ E+  ++  I D+ A ++ +
Sbjct: 52  ---RPDGGEVRYFGKDFDEEMKRIIGYLPEIDALYDNMTVSEYLNLFADIYDVRADIDGL 108

Query: 530 LNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARK 589
           L R  L D  +     S+LS G + +  IA  L   P VL+ DE    LD  T++ +A  
Sbjct: 109 LERLNLPDKYI-----SDLSKGMRRKVSIARTLLHDPEVLVYDEPTGGLDPTTSLSIAEL 163

Query: 590 VSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
           + E+  E G   V   H    V+ +  DKV+ +  G  +   SL
Sbjct: 164 LRELA-ERGKIIVFSAHNMYYVERI-ADKVVVMKGGKALYFGSL 205


>gi|11498589 ABC transporter, ATP-binding protein [Archaeoglobus fulgidus]
           >gi|7445781|pir||H69372 ABC transporter, ATP-binding
           protein homolog - Archaeoglobus fulgidus
           >gi|2649613|gb|AAB90258.1| (AE001036) ABC transporter,
           ATP-binding protein [Archaeoglobus fulgidus]
           Length = 217
           
 Score = 72.2 bits (174), Expect = 2e-11
 Identities = 63/211 (29%), Positives = 103/211 (47%), Gaps = 27/211 (12%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E+++L K FG      ++ VL+NLNF ++ G  VAV+G +GAGK+TL++++ G +     
Sbjct: 3   EVRNLSKRFG------RKLVLKNLNFEVDAGR-VAVLGQNGAGKSTLVKMVAGIL----- 50

Query: 478 EKYRPTSGKIEV-------PKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAVEVL 530
              RPT G+++V         + +  + I       +G  T+ E++       N+  ++ 
Sbjct: 51  ---RPTEGEVKVFGKDPSASPDVRERIGIATHNPMLYGELTVRENLEFYAGIYNSKPKLE 107

Query: 531 NRAGLSDAVLY-RAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARK 589
             A   D + Y   K SELS G  +R  +A  L   P++L++DE  + LD      V +K
Sbjct: 108 ELARKFDFLEYLDTKVSELSRGYLQRVSMAKALINDPDLLILDEVTSGLDA----TVRKK 163

Query: 590 VSEIVREAGITAVIITHRPEVVKALDPDKVL 620
           V EIV     T +  TH     K  +   VL
Sbjct: 164 VLEIVGTFQGTLLFTTHNLNEAKVCEAFIVL 194


>pir||T30882 multidrug resistance protein 1 - Aspergillus flavus
            >gi|2673947|gb|AAB88655.1| (U62931) multidrug resistance
            protein 1 [Aspergillus flavus] >gi|2673949|gb|AAB88656.1|
            (U62932) multidrug resistance protein 1 [Aspergillus
            flavus]
            Length = 1307
            
 Score = 72.2 bits (174), Expect = 2e-11
 Identities = 64/227 (28%), Positives = 102/227 (44%), Gaps = 39/227 (17%)

Query: 433  IQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKN 492
            +++P+LR+LN TI PG+ VA+VGASG+GK+T + L+        E  Y P  G + V   
Sbjct: 1073 LEQPILRHLNLTIKPGQFVALVGASGSGKSTTIALL--------ERFYDPLKGGVYVDGK 1124

Query: 493  AKVSVLIPG--------EIEPEFGSETILEHVYRKIRDLNAAVEVLNRAGLSDAVLY--- 541
              +++ +            EP     TI E++       +   + L +A   DA +Y   
Sbjct: 1125 NIITLEMSSYRSHLALISQEPTLFQGTIRENILLGSNTPHVTDDFLVKA-CKDANIYDFI 1183

Query: 542  -----------RAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKV 590
                         K   LS GQK+R  IA  L   P +LL+DE  + LD+ +   V   +
Sbjct: 1184 LSLPQGFNTIVGNKGGMLSGGQKQRIAIARALIRNPKILLLDEATSALDSESEKVVQAAL 1243

Query: 591  SEIVREAGITAVIITH------RPEVVKALDPDKVLFVGYGTVIVRK 631
                R  G T + + H      R +++  LD  +V+  G    ++RK
Sbjct: 1244 DAAAR--GRTTIAVAHRLSTIQRADLIYVLDQGEVVESGTHRELLRK 1288


>pir||T35147 glutamate uptake system ATP-binding protein - Streptomyces
           coelicolor >gi|2687342|emb|CAA15883.1| (AL020958)
           glutamate uptake system ATP-binding protein
           [Streptomyces coelicolor A3(2)]
           Length = 258
           
 Score = 72.2 bits (174), Expect = 2e-11
 Identities = 70/227 (30%), Positives = 115/227 (49%), Gaps = 32/227 (14%)

Query: 419 IQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLIL-------GA 471
           ++ + K FG  H      VL++++ TI  GEVV V+G SG+GK+TL R I        G+
Sbjct: 20  LKSVNKHFGALH------VLQDIDLTIQRGEVVVVIGPSGSGKSTLCRTINRLETVDDGS 73

Query: 472 IKGYWEEKYRPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEHV---YRKIRDLNA--- 525
           I    + K  P  GK      A V ++   +    F  +T+LE+V     K+R ++A   
Sbjct: 74  IT--IDGKPLPAEGKELARLRADVGMVF--QSFNLFAHKTVLENVTLGQVKVRKVDAKKA 129

Query: 526 ---AVEVLNRAGL-SDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTL 581
              A  +L+R G+ + A  Y A   +LS GQ++R  IA  LA  P V+L DE  + LD  
Sbjct: 130 EEKARALLDRVGVGAQADKYPA---QLSGGQQQRVAIARALAMDPKVMLFDEPTSALDPE 186

Query: 582 TAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
               V   + ++  E G+T +++TH     ++   ++V+F+  G ++
Sbjct: 187 MINEVLEVMKQLA-EDGMTMIVVTHEMGFARSA-ANRVVFMADGRIV 231


>pir||G72406 hypothetical protein TM0191 - Thermotoga maritima (strain MSB8)
           >gi|4980687|gb|AAD35283.1|AE001704_4 (AE001704)
           iron(III) ABC transporter, ATP-binding protein, putative
           [Thermotoga maritima]
           Length = 258
           
 Score = 72.2 bits (174), Expect = 2e-11
 Identities = 56/203 (27%), Positives = 99/203 (48%), Gaps = 14/203 (6%)

Query: 435 RPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAK 494
           + +L N+ F+   GE++A++G +GAGK+TLL+ I G +K    E +     +      A+
Sbjct: 14  KKILDNVTFSAQKGELIAILGPNGAGKSTLLKCIAGILKCQGVEIFSKPLEQYTRRDLAR 73

Query: 495 VSVLIPGEIEPEFGSETILEHVYRK--------IRDLNAAVEVLNRAGLSDAVLYRAKFS 546
           +   +P  I+P   +   L  + RK          D+     V+ R  L   V  RAK  
Sbjct: 74  IVGYVPQRIDPGMLNVYNLILLGRKPYVSVSPSKEDIEIVNRVVERLNLQHLVFQRAK-- 131

Query: 547 ELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITH 606
            LS G+ ++  IA  L + P +LL+DE   +LD    + +   V + V+   + A+++ H
Sbjct: 132 NLSGGELQKVSIARALVQEPEILLLDEPTNNLDPKNQIEIMEIVQDFVKSRKM-ALVVMH 190

Query: 607 RPEVVKALD-PDKVLFVGYGTVI 628
             E+  AL   D+ +F+  G ++
Sbjct: 191 --EINLALRFADRFIFMKDGKIV 211


>gb|AAF47525.1| (AE003472) CG7955 gene product [alt 3] [Drosophila melanogaster]
           >gi|7292114|gb|AAF47526.1| (AE003472) CG7955 gene
           product [alt 2] [Drosophila melanogaster]
           Length = 606
           
 Score = 72.2 bits (174), Expect = 2e-11
 Identities = 60/215 (27%), Positives = 106/215 (48%), Gaps = 37/215 (17%)

Query: 435 RPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGK-------- 486
           +P+ R+L+FTI  G+ VA+VG SG+GK++++RL+           + P SGK        
Sbjct: 361 KPIFRDLSFTIPAGKNVAIVGGSGSGKSSMVRLLF--------RFFEPNSGKVLIGGQDI 412

Query: 487 --IEVPKNAKVSVLIPGEIEPEFGSETILEH--VYRKIRDLNAAVEVLNR-AGLSDAVL- 540
             +++    KV  ++P   +        +EH   Y  +   +A V+   R A L D+++ 
Sbjct: 413 SAVDLESLRKVIAVVP---QDSVLFHNTIEHNIHYGNLSKSHAEVQNAARMADLHDSIMS 469

Query: 541 ----YRAKFSE----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSE 592
               Y  +  E    LS G+K+R  IA  + +   +L+ DE  + LD++T   + + ++ 
Sbjct: 470 WPGQYSTQVGERGLKLSGGEKQRVAIARAILKNTPILIFDEATSSLDSITEHNILQALTR 529

Query: 593 IVREAGITAVIITHRPEVVKALDPDKVLFVGYGTV 627
               +G T++ I HR   VK  D D++L +  G V
Sbjct: 530 AT--SGRTSICIAHRLSTVK--DADEILVLENGRV 560


>dbj|BAB04000.1| (AP001508) ABC transporter (ATP-binding protein) [Bacillus
           halodurans]
           Length = 213
           
 Score = 72.2 bits (174), Expect = 2e-11
 Identities = 61/213 (28%), Positives = 104/213 (48%), Gaps = 26/213 (12%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLI-------LG 470
           E+ D+ K+F          VLR+ N TI+ GE++A+ G SG+GKTT+L +I        G
Sbjct: 7   ELTDISKSFH------SETVLRDFNLTIDRGEMIAITGPSGSGKTTILNIIGLLEKEDRG 60

Query: 471 AIKGYWEEKYRPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAA---- 526
            ++ + + K    S +    + +K++ L       +   ET+ +++   +  +N +    
Sbjct: 61  TVRLFGKNKPAYHSKQALQFRKSKIAYLFQNFALMD--DETVSKNLDVPLELINGSRTVK 118

Query: 527 ----VEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLT 582
                EVL + GL + +    K   LS G+++R  IA LL    ++LL DE    LD   
Sbjct: 119 QQKKKEVLEKVGLFNKL--NKKVHSLSGGEQQRVAIARLLLRPCDLLLADEPTGSLDMAN 176

Query: 583 AMRVARKVSEIVREAGITAVIITHRPEVVKALD 615
              +   + ++ +E G+T VI+TH PEV    D
Sbjct: 177 RNVILDLLCQLNKE-GMTIVIVTHDPEVADRCD 208


>pir||D69858 ABC transporter (ATP-binding protein) homolog yknY - Bacillus
           subtilis >gi|2633807|emb|CAB13309.1| (Z99111) similar to
           ABC transporter (ATP-binding protein) [Bacillus
           subtilis] >gi|3282120|gb|AAC24910.1| (AF012285) YknY
           [Bacillus subtilis]
           Length = 230
           
 Score = 71.8 bits (173), Expect = 2e-11
 Identities = 59/218 (27%), Positives = 106/218 (48%), Gaps = 36/218 (16%)

Query: 437 VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVP------ 490
           VL +++  I+ GE V+++G SG+GK+T++ +I G +        RPTSG  ++       
Sbjct: 20  VLHSIDLDIHQGEYVSIMGPSGSGKSTIMNII-GCLD-------RPTSGTYQLDGEDISS 71

Query: 491 ---------KNAKVSVLIPG-EIEPEFGSETILE------HVYRKIRDLNAAVEVLNRAG 534
                    +N  +  +    ++ P   ++  +E       + +K R    A   L + G
Sbjct: 72  YKDKELAAVRNRSIGFVFQQFQLLPRLNAKKNVELPMIYSGIGKKERQ-ERAERALEKVG 130

Query: 535 LSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIV 594
           L+D +L+    +ELS GQK+R  IA  +   P ++L DE    LDT T+  +  + + + 
Sbjct: 131 LADRMLHMP--NELSGGQKQRVAIARAIVNEPKLILADEPTGALDTKTSEAIMDQFTALN 188

Query: 595 REAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKS 632
            E G T V++TH PEV      ++++ V  G ++   S
Sbjct: 189 AE-GTTIVLVTHEPEVADC--TNRIVMVRDGNIVPASS 223


>pir||S45043 expZ protein - Bacillus subtilis (fragment)
           >gi|494958|emb|CAA55930.1| (X79387) ExpZ [Bacillus
           subtilis]
           Length = 425
           
 Score = 71.8 bits (173), Expect = 2e-11
 Identities = 55/185 (29%), Positives = 88/185 (46%), Gaps = 36/185 (19%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E+Q++ KAFG      +R + +N NFTI  GE VA++G +G+GKTTLL +ILG       
Sbjct: 171 EVQNVTKAFG------ERTLFKNANFTIQHGEKVAIIGPNGSGKTTLLNIILG------- 217

Query: 478 EKYRPTSGKIEVPKNAKVSVL------IPGEIEPE--FGSETILE--HVYRKIRDLNAAV 527
                  G + V  +A +  L      +P E  PE  F +ET     HV   +R L    
Sbjct: 218 --QETAEGSVWVSPSANIGYLTQEVFDLPLEQTPEELFENETFKARGHVQNLMRHLGFT- 274

Query: 528 EVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVA 587
                     A  +      +S G++ + K+ + + E  +VL++DE   HLD  +  ++ 
Sbjct: 275 ----------AAQWTEPIKHMSMGERVKIKLMAYILEEKDVLILDEPTNHLDLPSREQLE 324

Query: 588 RKVSE 592
             +S+
Sbjct: 325 ETLSQ 329


>pir||T28812 hypothetical protein C54D1.1 - Caenorhabditis elegans
            >gi|1166606|gb|AAC48149.1| (U46673) Similar to
            multidrug-resistance protein; coded for by C. elegans
            cDNA yk13b2.3; coded for by C. elegans cDNA yk13b2.5;
            coded for by C. elegans cDNA yk23f10.3; coded for by C.
            elegans cDNA yk23f10.5 [Caenorhabditis elegans]
            Length = 1283
            
 Score = 71.8 bits (173), Expect = 2e-11
 Identities = 67/269 (24%), Positives = 120/269 (43%), Gaps = 42/269 (15%)

Query: 391  EMLEGPIVFKNVTKVFES------ELDIKGLPQEIQDLLKAFGVRHRVIQRP---VLRNL 441
            +  +  I  +NV +V          L  +GL  +++  L    V  R   RP   VL NL
Sbjct: 1002 DFTKAQIAAENVMRVIREPPVDMDNLSEEGLRPKLEGNLCLKDVSFRYPSRPIVPVLTNL 1061

Query: 442  NFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVSV---- 497
            N  +  GE +A+VG SG+GK++++ L        ++  Y  T G + + K    S+    
Sbjct: 1062 NLKVRGGESIALVGPSGSGKSSVISL--------FQRMYNATDGVVIIDKYNIKSINPAY 1113

Query: 498  ----LIPGEIEPEFGSETILEHVYRKIRDLNAAVE-VLNRAGLSDAVLYRAKF------- 545
                ++    EP+  S TI E++   + +  A ++ V+  A ++D   +           
Sbjct: 1114 LRRCIVQVGQEPDLFSFTIKENIAFGMMESEATIDKVIEAAKIADIHNFITSLPQGYDTE 1173

Query: 546  -----SELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVR--EAG 598
                 ++LS GQK+R  IA  +  +P VLL+DE  + LD+ +   V      + R  +  
Sbjct: 1174 VGEFGAQLSGGQKQRIAIARAIIRKPTVLLLDEATSALDSASEREVQNAFERVKRSTKTQ 1233

Query: 599  ITAVIITHRPEVVKALDPDKVLFVGYGTV 627
             T + I HR   ++  + DK+  + +G +
Sbjct: 1234 CTCIQIAHRLSTIR--NVDKIYVIVHGEI 1260


 Score = 69.9 bits (168), Expect = 8e-11
 Identities = 58/214 (27%), Positives = 100/214 (46%), Gaps = 37/214 (17%)

Query: 437 VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVS 496
           VLR ++F +  GE +A+VG+SG+GK+TL  L+L          Y PT G I +     + 
Sbjct: 367 VLRGISFKVEAGEKIAIVGSSGSGKSTLTALLL--------RFYDPTKGAI-LLDGENIK 417

Query: 497 VLIPGEI---------EPEFGSETILEHVYRKIRDLNAAVEVLNRA-----------GLS 536
            + P ++         EP     TI +++  +   L+A  + +N A            L 
Sbjct: 418 TMCPDDLRGQCSLVSQEPVLFDGTISDNI--RYGRLDATQQEINDAARKVGAWKFINSLP 475

Query: 537 DAVLYRA--KFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIV 594
           D +  R   +  +LS GQK+R  IA  +  +P VL+ DE  + LD +    V   +   +
Sbjct: 476 DGMQTRVGERGHQLSGGQKQRVAIARAVIRKPIVLIFDEATSALDNIHEEEVNAAID--L 533

Query: 595 REAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
              G+T + I HR   +K  + D+++ +  G ++
Sbjct: 534 ASEGLTTITIAHRLSTIK--NSDRIIVLHEGKIV 565


>sp|P39115|EXPZ_BACSU NUCLEOTIDE BINDING PROTEIN EXPZ >gi|7445764|pir||G69620 ATP-binding
           transport protein expZ - Bacillus subtilis
           >gi|1881367|dbj|BAA19394.1| (AB001488) PROBABLE
           ATP-BINDING TRANSPORT PROTEIN [Bacillus subtilis]
           >gi|2632861|emb|CAB12368.1| (Z99106) ATP-binding
           transport protein [Bacillus subtilis]
           >gi|2632874|emb|CAB12380.1| (Z99107) ATP-binding
           transport protein [Bacillus subtilis]
           Length = 547
           
 Score = 71.8 bits (173), Expect = 2e-11
 Identities = 55/185 (29%), Positives = 88/185 (46%), Gaps = 36/185 (19%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E+Q++ KAFG      +R + +N NFTI  GE VA++G +G+GKTTLL +ILG       
Sbjct: 293 EVQNVTKAFG------ERTLFKNANFTIQHGEKVAIIGPNGSGKTTLLNIILG------- 339

Query: 478 EKYRPTSGKIEVPKNAKVSVL------IPGEIEPE--FGSETILE--HVYRKIRDLNAAV 527
                  G + V  +A +  L      +P E  PE  F +ET     HV   +R L    
Sbjct: 340 --QETAEGSVWVSPSANIGYLTQEVFDLPLEQTPEELFENETFKARGHVQNLMRHLGFT- 396

Query: 528 EVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVA 587
                     A  +      +S G++ + K+ + + E  +VL++DE   HLD  +  ++ 
Sbjct: 397 ----------AAQWTEPIKHMSMGERVKIKLMAYILEEKDVLILDEPTNHLDLPSREQLE 446

Query: 588 RKVSE 592
             +S+
Sbjct: 447 ETLSQ 451


>gb|AAD15830.1| (AF062387) TAP2 protein [Xenopus laevis]
           Length = 720
           
 Score = 71.8 bits (173), Expect = 2e-11
 Identities = 69/247 (27%), Positives = 109/247 (43%), Gaps = 45/247 (18%)

Query: 393 LEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVA 452
           L G   FKNVT  + S  D                        P L+N++F + PG V A
Sbjct: 466 LRGQFEFKNVTFSYPSRPDA-----------------------PSLQNVSFKLPPGSVTA 502

Query: 453 VVGASGAGKTTLLRLI-------LGAI--KGYWEEKYRPTSGKIEVPKNAKVSVLIPGEI 503
           +VG SG GKTT + L+       +GAI   G    +Y+      +V   A+  VL  G I
Sbjct: 503 LVGPSGGGKTTCVSLLERFYEPQIGAILLDGIPLGEYKHQYLHSKVALVAQEPVLFAGTI 562

Query: 504 EPEFG------SETILEHVYRKIRDLNAAVEVLNRAGLSDAVLYRAKFSELSTGQKERAK 557
               G      SE  L+   RK +  +  +  + +   +D +      ++LS GQK+R  
Sbjct: 563 RENIGYGLKDISEKQLKEAARKAK-ADTFISEMEKLYDTDVL---DSGAQLSAGQKQRVA 618

Query: 558 IASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPD 617
           +A  LA +P +L++DE ++ LD  T   + + +  +     ++ +II HR   ++  D  
Sbjct: 619 LARALARKPKLLILDEASSCLDAETEHEIQQSLQTL---PDVSLLIIAHRLRTIQKADNI 675

Query: 618 KVLFVGY 624
            VL  GY
Sbjct: 676 LVLEGGY 682


>gb|AAD49436.1|AF083642_1 (AF083642) P-glycoprotein [Onchocerca volvulus]
            Length = 1278
            
 Score = 71.8 bits (173), Expect = 2e-11
 Identities = 64/215 (29%), Positives = 101/215 (46%), Gaps = 33/215 (15%)

Query: 434  QRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNA 493
            QR VL  LN     G+ VAV G SG+GK+T++ L+        E  YR  SG++ +  N+
Sbjct: 1051 QRNVLNGLNLAAYAGQTVAVTGPSGSGKSTVIALL--------ERFYRFNSGQLTLDDNS 1102

Query: 494  --KVS-------VLIPGEIEPEFGSETILEHVY-----RKIRDLNAAVEVLNRAGLSDAV 539
              K+S       + + G+ EP   S TILE++      + + D+  A ++ N     +  
Sbjct: 1103 ITKISLRYLREQIALVGQ-EPILFSGTILENILLGTTGKTLSDVREACKIANIIDFIETS 1161

Query: 540  L--YRAKFSE----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEI 593
               Y  +  E    LS GQK+R  IA  L   P +LL+DE  + LD      V + +   
Sbjct: 1162 PKGYDTEVGEHGVQLSGGQKQRIAIARALVRNPKILLLDEATSALDAECERTVQQALD-- 1219

Query: 594  VREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
               +G T + + HR   ++    D++ FV  G V+
Sbjct: 1220 AASSGRTCITVAHRLSSIQ--HADQIFFVENGKVV 1252


>pir||G75548 ABC transporter, ATP-binding protein - Deinococcus radiodurans
           (strain R1) >gi|6457873|gb|AAF09790.1|AE001882_8
           (AE001882) ABC transporter, ATP-binding protein
           [Deinococcus radiodurans]
           Length = 354
           
 Score = 71.8 bits (173), Expect = 2e-11
 Identities = 58/211 (27%), Positives = 98/211 (45%), Gaps = 43/211 (20%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E++ L K+F       ++P +++++F+I  GE+V  +G +GAGK+T ++++ G +     
Sbjct: 48  EVRHLCKSFA------RKPAVQDISFSIPAGEIVGYLGPNGAGKSTTIKVLTGLLV---- 97

Query: 478 EKYRPTSGKIEVP-----KNAKVSVLIPGEIEPEFGSET-------------ILEHVYRK 519
               P SG++ V      K  +  V   G +   FG  T             +L HVYR 
Sbjct: 98  ----PDSGEVRVGGLVPWKQRRQHVARLGAV---FGQRTTLWWDLPVRESLELLRHVYR- 149

Query: 520 IRDLNAAVEVLNRAGLSDAV----LYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFA 575
              + AA    N AG ++ +            LS GQ+ RA +A+ L   P +L +DE  
Sbjct: 150 ---VPAARFAENLAGFTELLELGPFLNTPARALSLGQRMRADLAAALLHDPELLFLDEPT 206

Query: 576 AHLDTLTAMRVARKVSEIVREAGITAVIITH 606
             LD +   R+   V  +  E G+T ++ TH
Sbjct: 207 VGLDVVAKERIREFVKAVNAERGVTVLLTTH 237


>gb|AAF48177.1| (AE003489) CG1824 gene product [Drosophila melanogaster]
           Length = 761
           
 Score = 71.8 bits (173), Expect = 2e-11
 Identities = 60/212 (28%), Positives = 106/212 (49%), Gaps = 32/212 (15%)

Query: 437 VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEV------- 489
           VL++ + T+ PG+ VA+VGASG+GK+T+  L+        E  Y P++G I++       
Sbjct: 479 VLKDFSLTLRPGQTVALVGASGSGKSTIASLV--------ERFYEPSAGNIKLDGYKLSD 530

Query: 490 --PKNAKVSVLIPGEIEPEFGSETILEHV-YRK----IRDLNAAVEVLNR----AGLSD- 537
             P   + +VL   E +P     +ILE++ Y K      D+ AA  +         L D 
Sbjct: 531 ISPYWLRSNVLGFIEQQPVLFGTSILENIRYGKPDAGEEDVYAAARLSQSHDFVTALPDG 590

Query: 538 -AVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVRE 596
            A     + ++LS GQ++R  IA  L + P +L++DE  + LD  +   V + +  +V+ 
Sbjct: 591 YATHVGERGTQLSGGQRQRIAIARALLKNPRILILDEATSALDATSEAEVQKALDTVVQN 650

Query: 597 AGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
              T ++I HR   ++  + D ++ +  G V+
Sbjct: 651 R--TTLVIAHRLSTIR--NADLIVVLDQGRVV 678


>sp|P36637|SAPF_ECOLI PEPTIDE TRANSPORT SYSTEM ATP-BINDING PROTEIN SAPF
           >gi|7445934|pir||E64877 peptide transport system
           ATP-binding protein sapF - Escherichia coli
           >gi|470683|gb|AAA17671.1| (U08190) Shows similarity with
           ATP-binding proteins from other ABC-transport operons,
           Swiss Prot Accession Numbers P24137, P08007, P04285,
           P24136 [Escherichia coli] >gi|1279404|emb|CAA65941.1|
           (X97282) SapF protein [Escherichia coli]
           >gi|1742103|dbj|BAA14843.1| (D90766) Peptide transport
           system ATP-binding protein SapF. [Escherichia coli]
           >gi|1742112|dbj|BAA14851.1| (D90767) Peptide transport
           system ATP-binding protein SapF. [Escherichia coli]
           >gi|1787547|gb|AAC74372.1| (AE000227) putative
           ATP-binding protein of peptide transport system
           [Escherichia coli K12]
           Length = 268
           
 Score = 71.4 bits (172), Expect = 3e-11
 Identities = 62/239 (25%), Positives = 113/239 (46%), Gaps = 35/239 (14%)

Query: 418 EIQDLLKAFGVRHRVIQRPVL---RNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKG 474
           E+++L K F  R    +R  +   + L+FT+  G+ +A++G +G+GK+TL +++ G I+ 
Sbjct: 7   EVRNLSKTFRYRTGWFRRQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIE- 65

Query: 475 YWEEKYRPTSGKIEVP-----------KNAKVSVLIPG---EIEPEFGSETILEHVYRKI 520
                  PTSG++ +            ++ ++ ++       + P      IL+   R  
Sbjct: 66  -------PTSGELLIDDHPLHFGDYSFRSQRIRMIFQDPSTSLNPRQRISQILDFPLRLN 118

Query: 521 RDLNAA------VEVLNRAGL-SDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDE 573
            DL         +E +   GL  D V Y      L+ GQK+R  +A  L  RP V++ DE
Sbjct: 119 TDLEPEQRRKQIIETMRMVGLLPDHVSYYPHM--LAPGQKQRLGLARALILRPKVIIADE 176

Query: 574 FAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKS 632
             A LD     ++   + E+  + GI+ + +T    ++K +  D+VL +  G V+ R S
Sbjct: 177 ALASLDMSMRSQLINLMLELQEKQGISYIYVTQHIGMMKHIS-DQVLVMHQGEVVERGS 234


>sp|Q60350|Y035_METJA HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MJ0035
           >gi|2127733|pir||C64304 ABC transporter subunit -
           Methanococcus jannaschii >gi|1590838|gb|AAB98016.1|
           (U67462) ABC transporter subunit [Methanococcus
           jannaschii]
           Length = 250
           
 Score = 71.4 bits (172), Expect = 3e-11
 Identities = 55/214 (25%), Positives = 109/214 (50%), Gaps = 29/214 (13%)

Query: 435 RPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKI------- 487
           R +L+ +N T+   E+ A++G +GAGK+TL   I+G I G     Y+PT G+I       
Sbjct: 19  REILKGVNLTVEENEIHAIIGPNGAGKSTLAYTIMG-ISG-----YKPTKGRIIFKGVDI 72

Query: 488 ---EVPKNAKVSVLIPGEIEPEFGSETILEHV-------YRKIRDL--NAAVEVLNRAGL 535
               + + A++ + +  +    F    +  ++       Y+K +++      E L    L
Sbjct: 73  IDKNITERARMGMTLAWQEPARFEGIKVKNYLMLGMNEKYKKDKEIAEEKIREALKLVNL 132

Query: 536 S-DAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIV 594
             D  L R     LS G+++R ++AS++   P++ ++DE  + +D ++   + ++V + +
Sbjct: 133 DPDKYLDRYVDETLSGGERKRIELASIICMEPDLAILDEPDSGIDIVSFDEI-KRVFDYL 191

Query: 595 REAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
           ++ G + ++ITHR E+  A   D+V  +  G VI
Sbjct: 192 KDKGCSLLVITHREEL--AEHADRVSLICAGEVI 223


>pir||H71302 probable ABC transporter, ATP-binding protein - syphilis spirochete
           >gi|3322909|gb|AAC65587.1| (AE001236) ABC transporter,
           ATP-binding protein [Treponema pallidum]
           Length = 259
           
 Score = 71.4 bits (172), Expect = 3e-11
 Identities = 60/212 (28%), Positives = 103/212 (48%), Gaps = 16/212 (7%)

Query: 432 VIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGK----I 487
           +  RP+L++LN T+N GEV AV+G +GAGK+TL   I+G      E       G+    +
Sbjct: 14  IADRPILKSLNLTLNTGEVHAVMGPNGAGKSTLAGTIVGNPHCTIERGEIYFQGQCINDV 73

Query: 488 EVPKNAKVSVLIPGEIEPEFGSETILEHV-YRKIRDLNAAVEVLN----------RAGLS 536
            V + A+  + +  +   E    ++ E +   K   L   V VL+          R  +S
Sbjct: 74  PVYERARRGIFLSFQTPEEVPGLSVEEFLRAAKEAVLGTKVSVLDFHTQLRAKLARLRIS 133

Query: 537 DAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVRE 596
           +A   R      S G+K++ +I  L    P + ++DE  + LD + A R+  +  + +R 
Sbjct: 134 EAYASRGLNVGFSGGEKKKNEILQLAVLEPKLAILDETDSGLD-VDATRIVFEGIDDIRT 192

Query: 597 AGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
             +  +IITH  EV++ + PD V  +  GT++
Sbjct: 193 PDMGFLIITHHREVLEYIKPDVVHILVDGTIV 224


>gi|10956101 ABC transporter subunit PenL [Pediococcus pentosaceus]
           >gi|10956124|ref|NP_037576.1| putative ABC transporter
           ATP-binding subunit [Pediococcus pentosaceus]
           >gi|4587880|gb|AAD25906.1|AF069302_15 (AF069302) ABC
           transporter subunit PenL [Pediococcus pentosaceus]
           >gi|5091682|gb|AAD39629.1|AF033858_12 (AF033858)
           putative ABC transporter ATP-binding subunit
           [Pediococcus pentosaceus]
           Length = 313
           
 Score = 71.4 bits (172), Expect = 3e-11
 Identities = 62/235 (26%), Positives = 112/235 (47%), Gaps = 42/235 (17%)

Query: 417 QEIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYW 476
           ++I  +L    V   + Q+ V+ +++F++  G+++A++G +GAGKTT++RLI   I+   
Sbjct: 2   EDIPLILTLSKVNKSISQKKVINDVSFSLEKGKILALLGPNGAGKTTIIRLITSLIE--- 58

Query: 477 EEKYRPTSGKIEV------PKNAK--VSVLIPGEIEPEFGSETILE-------------- 514
                  SG I V      P N +  +SV   G +   + + TI E              
Sbjct: 59  -----QDSGVISVFNGDINPSNIRQNISVQNDGNL---YENLTIFENLKIWGGFYEIPED 110

Query: 515 HVYRKIRDLNAAVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEF 574
           H+  KI +L +  E+  R          +K  ELS G K++  I   L   P +L++DE 
Sbjct: 111 HLEVKISELTSRFEISER--------LNSKVGELSKGMKQKVLIIRALLTNPKLLILDEP 162

Query: 575 AAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIV 629
            + LD      + + ++E V+    T ++ TH+   ++++  D VL +  G V+V
Sbjct: 163 TSGLDPYMIDLLTKILTEYVKRHETTIIMATHQLLGLESI-ADDVLILNKGEVVV 216


>gb|AAF55241.1| (AE003710) CG4225 gene product [Drosophila melanogaster]
           Length = 866
           
 Score = 71.4 bits (172), Expect = 3e-11
 Identities = 59/214 (27%), Positives = 105/214 (48%), Gaps = 27/214 (12%)

Query: 434 QRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLIL-------GAIKGYWEEKYRPTSGK 486
           ++ VLRN++FT+  G+ VA+VG SGAGK+T++RL+        GAI           + K
Sbjct: 588 EKIVLRNVSFTVPAGKTVAIVGPSGAGKSTIMRLLFRFYDVQTGAI------LIDGQNIK 641

Query: 487 IEVPKNAKVSVLIPGEIEPEFGSETILEHVYRKIRDLNAAV-EVLNRAGLSDAVL----- 540
           +   ++ + ++ +  +    F +       Y K+   + AV E    A + + +L     
Sbjct: 642 LVQQQSLRKAIGVVPQDTVLFNNTIFYNIEYAKLGASDEAVYEAARAADIHERILGFPEK 701

Query: 541 YRAKFSE----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVRE 596
           Y  K  E    LS G+K+R  IA  L + P ++L+DE  + LDT T   +   ++ +   
Sbjct: 702 YETKVGERGLRLSGGEKQRVAIARTLLKAPIIVLLDEATSALDTHTERNIQAALARVC-- 759

Query: 597 AGITAVIITHRPEVVKALDPDKVLFVGYGTVIVR 630
           A  T +I+ HR   +  +  D++L +  G++  R
Sbjct: 760 ANRTTIIVAHRLSTI--IHADEILVLQQGSIAER 791


>pir||E81936 probable amino acid permease ATP-binding protein NMA0900 [imported]
           - Neisseria meningitidis (group A strain Z2491)
           >gi|7379613|emb|CAB84178.1| (AL162754) putative amino
           acid permease ATP-binding protein [Neisseria
           meningitidis Z2491]
           Length = 242
           
 Score = 71.4 bits (172), Expect = 3e-11
 Identities = 67/207 (32%), Positives = 105/207 (50%), Gaps = 22/207 (10%)

Query: 437 VLRNLNFTINPGEVVAVVGASGAGKTTLLRLI--LGAIKG--YWEEKYRPTSGKIEVPK- 491
           V+  +N  I  GEVV V G SG+GK+TL+R +  L +I+    W +       K ++ K 
Sbjct: 16  VINGVNLEIKKGEVVVVCGPSGSGKSTLIRTVNQLESIESGEIWVDGVNVADPKTDLNKI 75

Query: 492 NAKVSVLIPG-EIEPEFGSETILEHVY---RKIRDLNA------AVEVLNRAGLSDAVLY 541
             +V  +     + P     T+LE++     K++  NA      A+E+L R GL  A   
Sbjct: 76  REEVGFVFQSFNLYPHL---TVLENITLAPMKVKGQNAEQAEKKAMELLERVGL--AHKK 130

Query: 542 RAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITA 601
            A  S+LS GQ++R  IA  LA  P V+L DE  + LD      V  KV + + E+G+T 
Sbjct: 131 DAFPSQLSGGQQQRVAIARGLAMEPRVMLFDEPTSALDPEMVGEVL-KVMKDLAESGMTM 189

Query: 602 VIITHRPEVVKALDPDKVLFVGYGTVI 628
           + +TH     + +  D+V+FV  G ++
Sbjct: 190 MCVTHEMGFAREV-ADRVIFVDKGQIL 215


>dbj|BAB05744.1| (AP001514) ABC transporter (ATP-binding protein) [Bacillus
           halodurans]
           Length = 539
           
 Score = 71.4 bits (172), Expect = 3e-11
 Identities = 62/237 (26%), Positives = 111/237 (46%), Gaps = 20/237 (8%)

Query: 389 KVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPG 448
           ++E+L+ PI+        + +LD     +   D++    V     +R +  ++   +   
Sbjct: 304 RIELLKKPILQHK-----KVDLDFHIQNRSGTDVIMMENVAKTYGERELFHDVQLHVRFQ 358

Query: 449 EVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVSVLIPGEIEPEFG 508
           E VA+VG +G+GK+TLL +ILG        K +P  G+I++  N  +  L     E + G
Sbjct: 359 ERVAIVGENGSGKSTLLNMILG--------KQQPEKGRIQIGSNVSIGYLSQHNEEMD-G 409

Query: 509 SETILEHVYRKIRDLNA-AVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPN 567
            +TILE    K+      A  +L R       ++R K  +LS G++ R ++A L+ +R N
Sbjct: 410 KKTILEEFRAKVTVTEGEARHILARYLFYGNTVFR-KVKDLSGGERMRLRLAQLVHQRHN 468

Query: 568 VLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGY 624
           +L++DE   HLD    +     + E + E   T + ++H    +  L P      G+
Sbjct: 469 LLILDEPTNHLD----IDSREVLEEALSEFQGTVIAVSHDRYFLDRLFPVTYWLAGH 521


>sp|Q00748|MDR5_DROME MULTIDRUG RESISTANCE PROTEIN HOMOLOG 65 (P-GLYCOPROTEIN 65)
           >gi|103252|pir||B41249 multidrug resistance protein
           homolog Mdr65 - fruit fly  (Drosophila melanogaster)
           >gi|157875|gb|AAA28680.1| (M59077) P-glycoprotein
           [Drosophila melanogaster]
           Length = 1302
           
 Score = 71.0 bits (171), Expect = 4e-11
 Identities = 65/231 (28%), Positives = 112/231 (48%), Gaps = 36/231 (15%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E QD+   +  R  VI   V R LN  I  G+ VA+VG+SG GK+T ++L+        +
Sbjct: 406 EFQDVFFRYPSRPEVI---VHRGLNIRIRAGQTVALVGSSGCGKSTCVQLL--------Q 454

Query: 478 EKYRPTSGKI-----EVPKN----AKVSVLIPGEIEPEFGSETILEHV-YRKIRDLNAAV 527
             Y P  G +     ++ K      + ++ + G+ EP     TI +++ Y K       +
Sbjct: 455 RFYDPVFGSVLLDDLDIRKYNIQWLRSNIAVVGQ-EPVLFLGTIAQNISYGKPGATQKEI 513

Query: 528 EVL-NRAGLSDAVL-----YRAKF----SELSTGQKERAKIASLLAERPNVLLIDEFAAH 577
           E    +AG  + +      YR+      S+LS GQK+R  IA  L + P +LL+DE  + 
Sbjct: 514 EAAATQAGAHEFITNLPESYRSMIGERGSQLSGGQKQRIAIARALIQNPKILLLDEATSA 573

Query: 578 LDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
           LD  +  +V + +   +   G T ++++HR   ++    DK++F+  G V+
Sbjct: 574 LDYQSEKQVQQALD--LASKGRTTIVVSHRLSAIRG--ADKIVFIHDGKVL 620


>sp|P36371|TAP2_MOUSE ANTIGEN PEPTIDE TRANSPORTER 2 (APT2) (HISTOCOMPATIBILITY ANTIGEN
           MODIFIER 2) >gi|346732|pir||A44135 histocompatibility
           antigen modifier 2 - mouse >gi|199434|gb|AAA39609.1|
           (M90459) HAM2 [Mus musculus] >gi|2555194|gb|AAB81533.1|
           (AF027865) antigen processing transporter TAP2 [Mus
           musculus]
           Length = 702
           
 Score = 71.0 bits (171), Expect = 4e-11
 Identities = 60/220 (27%), Positives = 105/220 (47%), Gaps = 35/220 (15%)

Query: 434 QRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNA 493
           ++PVL+ L FT++PG V A+VG +G+GK+T+  L+        +  Y+PT G++ +    
Sbjct: 481 EKPVLQGLTFTLHPGTVTALVGPNGSGKSTVAALL--------QNLYQPTGGQLLLDGEP 532

Query: 494 KV---------SVLIPGEIEPEFGSETILEHVYRKIRDL-NAAVEVLNRAGLSDAVL--- 540
                       V++ G+ EP   S ++ +++   +RD  +A V    +A  +D  +   
Sbjct: 533 LTEYDHHYLHRQVVLVGQ-EPVLFSGSVKDNIAYGLRDCEDAQVMAAAQAACADDFIGEM 591

Query: 541 -------YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEI 593
                     K  +L+ GQK+R  IA  L   P VL++DE  + LD      +    S+ 
Sbjct: 592 TNGINTEIGEKGGQLAVGQKQRLAIARALVRNPRVLILDEATSALDAQCEQALQNWRSQG 651

Query: 594 VREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
            R    T ++I HR   V+  + D+VL +  G ++    L
Sbjct: 652 DR----TMLVIAHRLHTVQ--NADQVLVLKQGRLVEHDQL 685


>pir||T30855 multidrug resistance protein 2 - fluke (Schistosoma mansoni)
           >gi|425476|gb|AAA66477.1| (L26287) SMDR2 [Schistosoma
           mansoni]
           Length = 1254
           
 Score = 71.0 bits (171), Expect = 4e-11
 Identities = 69/257 (26%), Positives = 114/257 (43%), Gaps = 43/257 (16%)

Query: 398 VFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRP------VLRNLNFTINPGEVV 451
           +F  +  V E E   +G  + + D   +   RH     P      +L N   T+  G+ +
Sbjct: 337 IFATIDHVCEIEKKDRG--KILSDFDGSITFRHVNFNYPSRPDVTILVNFCLTVKSGQTI 394

Query: 452 AVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVSVLIPG--------EI 503
           A+VG+SG+GK+TL+ ++        +  Y PT G+I +       + I          + 
Sbjct: 395 ALVGSSGSGKSTLIHML--------QRFYDPTQGEILIQGVDLRELNIHNYRNQIGCVQQ 446

Query: 504 EPEFGSETILEHVYRKIRDLNAAVEVLNRAGLSDAV-------------LYRAKFSELST 550
           EP     TI E++   +  LNA  E ++ A +                 L   K S LS 
Sbjct: 447 EPVLFDGTIRENI--GLGKLNATDEEIHEAAIKANAHQFIMRLPQGYDTLVGEKGSNLSG 504

Query: 551 GQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEV 610
           GQK+R  IA +L  +P +LL+DE  + LDT +   V   + +IV   G T +II HR   
Sbjct: 505 GQKQRIAIARVLIRKPKLLLLDEATSALDTQSERIVQGALDKIV--GGCTVIIIAHRLST 562

Query: 611 VKALDPDKVLFVGYGTV 627
           +  ++ D ++ +  G +
Sbjct: 563 I--INADYIIVLDQGCI 577


>sp|Q61102|ABC7_MOUSE ATP-BINDING CASSETTE, SUB-FAMILY B, MEMBER 7, MITOCHONDRIAL
           (ATP-BINDING CASSETTE TRANSPORTER 7) (ABC TRANSPORTER 7
           PROTEIN) >gi|1167982|gb|AAC53152.1| (U43892) ABC
           transporter-7 [Mus musculus]
           Length = 694
           
 Score = 71.0 bits (171), Expect = 4e-11
 Identities = 62/214 (28%), Positives = 104/214 (47%), Gaps = 33/214 (15%)

Query: 437 VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVS 496
           VL  ++F +  G+ VA+VG SG+GK+T++RL+           Y P  G I +       
Sbjct: 429 VLNGVSFEVPAGKKVAIVGGSGSGKSTIVRLLF--------RFYEPQKGSIYLAGQNLQD 480

Query: 497 VLIPGEIEPEFG---SETILEH--VYRKI--RDLNAAVE----VLNRAGLSDAVL----- 540
           V +   +    G    + +L H  +Y  +   ++NA+ E    V   AGL DA+L     
Sbjct: 481 VSLE-SLRRAVGVVPQDAVLFHNTIYYNLLYGNINASPEEVYAVAKLAGLHDAILRMPHG 539

Query: 541 YRAKFSE----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVRE 596
           Y  +  E    LS G+K+R  IA  + + P V+L DE  + LD++T   +   + ++V+ 
Sbjct: 540 YDTQVGERGLKLSGGEKQRVAIARAILKNPPVILYDEATSSLDSITEETILGAMRDVVKH 599

Query: 597 AGITAVIITHRPEVVKALDPDKVLFVGYGTVIVR 630
              T++ I HR   V  +D D+++ +  G V  R
Sbjct: 600 R--TSIFIAHRLSTV--VDADEIIVLSQGKVAER 629


>gb|AAB41968.1| (U60091) TAP2 [Mus musculus castaneus]
           Length = 703
           
 Score = 71.0 bits (171), Expect = 4e-11
 Identities = 60/220 (27%), Positives = 105/220 (47%), Gaps = 35/220 (15%)

Query: 434 QRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNA 493
           ++PVL+ L FT++PG V A+VG +G+GK+T+  L+        +  Y+PT G++ +    
Sbjct: 482 EKPVLQGLTFTLHPGTVTALVGPNGSGKSTVAALL--------QNLYQPTGGQLLLDGEP 533

Query: 494 KV---------SVLIPGEIEPEFGSETILEHVYRKIRDL-NAAVEVLNRAGLSDAVL--- 540
                       V++ G+ EP   S ++ +++   +RD  +A V    +A  +D  +   
Sbjct: 534 LTEYDHHYLHRQVVLVGQ-EPVLFSGSVKDNIAYGLRDCEDAQVMAAAQAACADDFIGEM 592

Query: 541 -------YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEI 593
                     K  +L+ GQK+R  IA  L   P VL++DE  + LD      +    S+ 
Sbjct: 593 TNGINTEIGEKGGQLAVGQKQRLAIARALVRNPRVLILDEATSALDAQCEQALQNWRSQG 652

Query: 594 VREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
            R    T ++I HR   V+  + D+VL +  G ++    L
Sbjct: 653 DR----TMLVIAHRLHTVQ--NADQVLVLKQGRLVEHDQL 686


>gb|AAB41969.1| (U60092) TAP2 [Mus musculus castaneus]
           Length = 702
           
 Score = 71.0 bits (171), Expect = 4e-11
 Identities = 60/220 (27%), Positives = 105/220 (47%), Gaps = 35/220 (15%)

Query: 434 QRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNA 493
           ++PVL+ L FT++PG V A+VG +G+GK+T+  L+        +  Y+PT G++ +    
Sbjct: 481 EKPVLQGLTFTLHPGTVTALVGPNGSGKSTVAALL--------QNLYQPTGGQLLLDGEP 532

Query: 494 KV---------SVLIPGEIEPEFGSETILEHVYRKIRDL-NAAVEVLNRAGLSDAVL--- 540
                       V++ G+ EP   S ++ +++   +RD  +A V    +A  +D  +   
Sbjct: 533 LTEYDHHYLHRQVVLVGQ-EPVLFSGSVKDNIAYGLRDCEDAQVMAAAQAACADDFIGEM 591

Query: 541 -------YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEI 593
                     K  +L+ GQK+R  IA  L   P VL++DE  + LD      +    S+ 
Sbjct: 592 TNGINTEIGEKGGQLAVGQKQRLAIARALVRNPRVLILDEATSALDAQCEQALQNWRSQG 651

Query: 594 VREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
            R    T ++I HR   V+  + D+VL +  G ++    L
Sbjct: 652 DR----TMLVIAHRLHTVQ--NADQVLVLKQGRLVEHDQL 685


>gb|AAB41970.1| (U60087) TAP2 [Mus musculus]
           Length = 703
           
 Score = 71.0 bits (171), Expect = 4e-11
 Identities = 60/220 (27%), Positives = 105/220 (47%), Gaps = 35/220 (15%)

Query: 434 QRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNA 493
           ++PVL+ L FT++PG V A+VG +G+GK+T+  L+        +  Y+PT G++ +    
Sbjct: 482 EKPVLQGLTFTLHPGTVTALVGPNGSGKSTVAALL--------QNLYQPTGGQLLLDGEP 533

Query: 494 KV---------SVLIPGEIEPEFGSETILEHVYRKIRDL-NAAVEVLNRAGLSDAVL--- 540
                       V++ G+ EP   S ++ +++   +RD  +A V    +A  +D  +   
Sbjct: 534 LTEYDHHYLHRQVVLVGQ-EPVLFSGSVKDNIAYGLRDCEDAQVMAAAQAACADDFIGEM 592

Query: 541 -------YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEI 593
                     K  +L+ GQK+R  IA  L   P VL++DE  + LD      +    S+ 
Sbjct: 593 TNGINTEIGEKGGQLAVGQKQRLAIARALVRNPRVLILDEATSALDAQCEQALQNWRSQG 652

Query: 594 VREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
            R    T ++I HR   V+  + D+VL +  G ++    L
Sbjct: 653 DR----TMLVIAHRLHTVQ--NADQVLVLKQGRLVEHDQL 686


>gb|AAB41971.1| (U60088) TAP2 [Mus musculus]
           Length = 703
           
 Score = 71.0 bits (171), Expect = 4e-11
 Identities = 60/220 (27%), Positives = 105/220 (47%), Gaps = 35/220 (15%)

Query: 434 QRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNA 493
           ++PVL+ L FT++PG V A+VG +G+GK+T+  L+        +  Y+PT G++ +    
Sbjct: 482 EKPVLQGLTFTLHPGTVTALVGPNGSGKSTVAALL--------QNLYQPTGGQLLLDGEP 533

Query: 494 KV---------SVLIPGEIEPEFGSETILEHVYRKIRDL-NAAVEVLNRAGLSDAVL--- 540
                       V++ G+ EP   S ++ +++   +RD  +A V    +A  +D  +   
Sbjct: 534 LTEYDHHYLHRQVVLVGQ-EPVLFSGSVKDNIAYGLRDCEDAQVMAAAQAACADDFIGEM 592

Query: 541 -------YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEI 593
                     K  +L+ GQK+R  IA  L   P VL++DE  + LD      +    S+ 
Sbjct: 593 TNGINTEIGEKGGQLAVGQKQRLAIARALVRNPRVLILDEATSALDAQCEQALQNWRSQG 652

Query: 594 VREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
            R    T ++I HR   V+  + D+VL +  G ++    L
Sbjct: 653 DR----TMLVIAHRLHTVQ--NADQVLVLKQGRLVEHDQL 686


>gb|AAB41972.1| (U60089) TAP2 [Mus musculus]
           Length = 703
           
 Score = 71.0 bits (171), Expect = 4e-11
 Identities = 60/220 (27%), Positives = 105/220 (47%), Gaps = 35/220 (15%)

Query: 434 QRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNA 493
           ++PVL+ L FT++PG V A+VG +G+GK+T+  L+        +  Y+PT G++ +    
Sbjct: 482 EKPVLQGLTFTLHPGTVTALVGPNGSGKSTVAALL--------QNLYQPTGGQLLLDGEP 533

Query: 494 KV---------SVLIPGEIEPEFGSETILEHVYRKIRDL-NAAVEVLNRAGLSDAVL--- 540
                       V++ G+ EP   S ++ +++   +RD  +A V    +A  +D  +   
Sbjct: 534 LTEYDHHYLHRQVVLVGQ-EPVLFSGSVKDNIAYGLRDCEDAQVMAAAQAACADDFIGEM 592

Query: 541 -------YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEI 593
                     K  +L+ GQK+R  IA  L   P VL++DE  + LD      +    S+ 
Sbjct: 593 TNGINTEIGEKGGQLAVGQKQRLAIARALVRNPRVLILDEATSALDAQCEQALQNWRSQG 652

Query: 594 VREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
            R    T ++I HR   V+  + D+VL +  G ++    L
Sbjct: 653 DR----TMLVIAHRLHTVQ--NADQVLVLKQGRLVEHDQL 686


>gi|7549791 ATP-binding cassette, sub-family B, member 3; ATP dependent
           transport protein family member; peptide supply factor
           2; histocompatibility antigen modifier 2 [Mus musculus]
           >gi|1399929|gb|AAB41973.1| (U60090) TAP2 [Mus musculus]
           Length = 703
           
 Score = 71.0 bits (171), Expect = 4e-11
 Identities = 60/220 (27%), Positives = 105/220 (47%), Gaps = 35/220 (15%)

Query: 434 QRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNA 493
           ++PVL+ L FT++PG V A+VG +G+GK+T+  L+        +  Y+PT G++ +    
Sbjct: 482 EKPVLQGLTFTLHPGTVTALVGPNGSGKSTVAALL--------QNLYQPTGGQLLLDGEP 533

Query: 494 KV---------SVLIPGEIEPEFGSETILEHVYRKIRDL-NAAVEVLNRAGLSDAVL--- 540
                       V++ G+ EP   S ++ +++   +RD  +A V    +A  +D  +   
Sbjct: 534 LTEYDHHYLHRQVVLVGQ-EPVLFSGSVKDNIAYGLRDCEDAQVMAAAQAACADDFIGEM 592

Query: 541 -------YRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEI 593
                     K  +L+ GQK+R  IA  L   P VL++DE  + LD      +    S+ 
Sbjct: 593 TNGINTEIGEKGGQLAVGQKQRLAIARALVRNPRVLILDEATSALDAQCEQALQNWRSQG 652

Query: 594 VREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
            R    T ++I HR   V+  + D+VL +  G ++    L
Sbjct: 653 DR----TMLVIAHRLHTVQ--NADQVLVLKQGRLVEHDQL 686


>sp|P54718|YFIB_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN 1 IN GLVBC
           3'REGION >gi|7445716|pir||E69802 ABC transporter
           (ATP-binding protein) homolog yfiB - Bacillus subtilis
           >gi|1486244|dbj|BAA09106.1| (D50543) unknown [Bacillus
           subtilis] >gi|2633145|emb|CAB12650.1| (Z99108) similar
           to ABC transporter (ATP-binding protein) [Bacillus
           subtilis]
           Length = 573
           
 Score = 71.0 bits (171), Expect = 4e-11
 Identities = 59/220 (26%), Positives = 107/220 (47%), Gaps = 35/220 (15%)

Query: 429 RHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIE 488
           R+  + R  LRN++F+  P E +A++GA+G+GK+TL +LI           Y+P SG+I 
Sbjct: 338 RYPEMDREALRNVSFSAKPRETIAILGATGSGKSTLFQLI--------PRLYQPDSGRIY 389

Query: 489 VPKNAKVSVLIPGEIEPEFG---------SETILEHVY--RKIRDLNAAVEVLNRAGLSD 537
           + +     +   G +  + G         S TI E++   ++   L+  ++    A + +
Sbjct: 390 IDEKPVQDIPAEG-LRRQIGYVPQEVLLFSGTIKENIAWGKENASLDEIMDAAKLAQIHE 448

Query: 538 AVL-----YRAKFSE----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVAR 588
            +L     Y     +    LS GQK+R  IA  L  +P +LL+D+  + LD    ++   
Sbjct: 449 TILKLPNGYDTVLGQRGVNLSGGQKQRISIARALIRKPAILLLDDSTSALD----LQTEA 504

Query: 589 KVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
           K+ E +     T +IIT +  +  A+  D++L +  G +I
Sbjct: 505 KLLEAISTYHCTTLIITQK--ITTAMKADQILLLEDGELI 542


>pir||E69771 ABC transporter (ATP-binding protein) homolog ydbJ - Bacillus
           subtilis >gi|1881259|dbj|BAA19286.1| (AB001488) PROBABLE
           TRANSPORT ATP BINDING PROTEIN. [Bacillus subtilis]
           >gi|2632749|emb|CAB12256.1| (Z99106) similar to ABC
           transporter (ATP-binding protein) [Bacillus subtilis]
           Length = 308
           
 Score = 71.0 bits (171), Expect = 4e-11
 Identities = 56/220 (25%), Positives = 102/220 (45%), Gaps = 10/220 (4%)

Query: 420 QDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIK---GYW 476
           + +L   G+  ++  + +L+ ++  +  GE++ ++G +G+GKTTL+R+I+G +K   G  
Sbjct: 3   EPILHIEGLDKKIGSKQILKQISMDVMEGEIIGLLGPNGSGKTTLIRIIVGLLKQNSGSV 62

Query: 477 EEKYRPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEH---VYRKIRDLNAAVEVLNRA 533
                    + E    A  +++   E  P       L+H   +++KI D     EV+ R 
Sbjct: 63  TISGFQHDTEFEKAMEAVGAIVENPEFYPYLTGWENLKHFANMHKKIAD-ERLDEVVERV 121

Query: 534 GLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEI 593
           GL+ A+    K    S G ++R  IA  +  RP +L++DE    LD          + E+
Sbjct: 122 GLTSAI--HDKVKTYSLGMRQRLGIAQAILHRPKLLILDEPTNGLDPAGMKDFRDHIKEL 179

Query: 594 VREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
               G   +  TH    V+ L  D+V+ +  G +    SL
Sbjct: 180 AEMEGTAVLFATHLLREVEDL-CDRVIIIQKGEIKAEVSL 218


>gb|AAF50669.1| (AE003563) Mdr65 gene product [Drosophila melanogaster]
           >gi|7767568|gb|AAF69146.1|AF251286_1 (AF251286)
           P-glycoprotein [Drosophila melanogaster]
           >gi|7767570|gb|AAF69147.1|AF251287_1 (AF251287)
           P-glycoprotein [Drosophila melanogaster]
           Length = 1302
           
 Score = 71.0 bits (171), Expect = 4e-11
 Identities = 65/231 (28%), Positives = 112/231 (48%), Gaps = 36/231 (15%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           E QD+   +  R  VI   V R LN  I  G+ VA+VG+SG GK+T ++L+        +
Sbjct: 406 EFQDVFFRYPSRPEVI---VHRGLNIRIRAGQTVALVGSSGCGKSTCVQLL--------Q 454

Query: 478 EKYRPTSGKI-----EVPKN----AKVSVLIPGEIEPEFGSETILEHV-YRKIRDLNAAV 527
             Y P  G +     ++ K      + ++ + G+ EP     TI +++ Y K       +
Sbjct: 455 RFYDPVFGSVLLDDLDIRKYNIQWLRSNIAVVGQ-EPVLFLGTIAQNISYGKPGATQKEI 513

Query: 528 EVL-NRAGLSDAVL-----YRAKF----SELSTGQKERAKIASLLAERPNVLLIDEFAAH 577
           E    +AG  + +      YR+      S+LS GQK+R  IA  L + P +LL+DE  + 
Sbjct: 514 EAAATQAGAHEFITNLPESYRSMIGERGSQLSGGQKQRIAIARALIQNPKILLLDEATSA 573

Query: 578 LDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVI 628
           LD  +  +V + +   +   G T ++++HR   ++    DK++F+  G V+
Sbjct: 574 LDYQSEKQVQQALD--LASKGRTTIVVSHRLSAIRG--ADKIVFIHDGKVL 620


>gb|AAG32538.1| (AY005472) SalT [Streptococcus salivarius]
           Length = 722
           
 Score = 71.0 bits (171), Expect = 4e-11
 Identities = 66/250 (26%), Positives = 111/250 (44%), Gaps = 33/250 (13%)

Query: 404 KVFESELDIKGLPQEIQDL------------LKAFGVRHRVIQRPVLRNLNFTINPGEVV 451
           K +E  L+I  L  E  D             LK    ++ +    VL  +N  ++ GE V
Sbjct: 449 KHYERVLEISTLDNETNDTYKLSEDTDIEINLKNINYQYELNGAKVLNGINLKVHSGEFV 508

Query: 452 AVVGASGAGKTTLLRLILGAIK-GYWEEKYRPTS-GKIEVPKNAKVSVLIPGEIEPEFGS 509
           A++G SG+GKTTL +++LG +     +  Y   S  KI+      +S  +  +  P F  
Sbjct: 509 AIIGKSGSGKTTLAKMLLGYVSPSSGDITYNNISYSKIDKKDFRNISAFV-SQDSPMFDG 567

Query: 510 ETILE-HVYRKIRDLNAAVEVLNRAGLSD----------AVLYRAKFSELSTGQKERAKI 558
           + +    + R+       +E   R  + D           +L+R   S +S GQK+R  +
Sbjct: 568 DVMYNISLGRESVSGEQVIETCKRVSIYDDIRSMPMKFHTLLFRDNPS-ISGGQKQRISL 626

Query: 559 ASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDK 618
           A  L   P +L++DE  + LD    ++  R + + V     T V++THR   V+    DK
Sbjct: 627 ARELVTTPRILVLDEPTSALD----VKTERIIQKNVEALHCTRVLVTHRLNTVE--KADK 680

Query: 619 VLFVGYGTVI 628
           +L +  G +I
Sbjct: 681 ILIMDNGKII 690


>emb|CAA08835.1| (AJ009799) ABC transporter protein [Gallus gallus]
           Length = 1288
           
 Score = 70.6 bits (170), Expect = 5e-11
 Identities = 67/232 (28%), Positives = 106/232 (44%), Gaps = 34/232 (14%)

Query: 407 ESELDIKGLPQEIQDLLKAFGVRHRVIQRP---VLRNLNFTINPGEVVAVVGASGAGKTT 463
           +S  D    P  I+  L+   V      RP   +L+ LN  +N G+ VA+VG SG GK+T
Sbjct: 384 DSYSDAGHKPDHIKGNLEFQNVFFNYPSRPDVEILKGLNLKVNCGQTVALVGGSGCGKST 443

Query: 464 LLRLILGAIKGYWEEKYRPTSGKIEVP----KNAKVSVL--IPGEIEPE----------- 506
            ++LI        +  Y P  G I +     K+  V  L  I G +  E           
Sbjct: 444 TVQLI--------QRFYDPKEGTITIDGQDLKSLNVRYLREIIGVVNQEPVLFATTIAEN 495

Query: 507 --FGSETI-LEHVYRKIRDLNAAVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLA 563
             +G E + +E + R  ++ NA   ++      + V+   + +++S GQK+R  IA  L 
Sbjct: 496 IRYGREDVTMEEIERATKEANAYDFIMKLPKKFETVV-GERGAQMSGGQKQRIAIARALV 554

Query: 564 ERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALD 615
             P +LL+DE  + LDT  +  V +   +  RE G T V++ HR   V+  D
Sbjct: 555 HNPKILLLDEATSALDT-ESESVVQAALDKARE-GRTTVVVAHRLSTVRNAD 604


>emb|CAB37661.1| (AJ224479) cdd4-like protein [Bacillus sphaericus]
           Length = 311
           
 Score = 70.6 bits (170), Expect = 5e-11
 Identities = 61/228 (26%), Positives = 102/228 (43%), Gaps = 29/228 (12%)

Query: 418 EIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWE 477
           + Q+L K FG    V       N+N  I  GE+   +G +GAGKTT +R++LG +K    
Sbjct: 14  QTQNLSKNFGKEQAV------SNINLQIRKGEIYGFLGPNGAGKTTTIRMLLGLMK---- 63

Query: 478 EKYRPTSGKIEVPKN--AKVSVLIPGEIEPEFGSETILEHV--YRKIRDLNAAV------ 527
               P+SG I++ +    K  + I   +     + +   H+  Y  +  L   +      
Sbjct: 64  ----PSSGTIKIFQKDIVKDRIQILANVGSLVENPSYYPHLTAYENLEALRKILGVPKTR 119

Query: 528 --EVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMR 585
             EVL    L +A     K    S G K+R  IA+ L   P +L++DE    LD    + 
Sbjct: 120 IDEVLQTVRLKEAA--NKKVKGFSLGMKQRLGIAAALLHNPELLILDEPTNGLDPSGIIE 177

Query: 586 VARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKSL 633
           +   +  + +E G+T +I +H    +  +   +V  V  GT+I + S+
Sbjct: 178 IRNLIKRLPKEYGMTIIISSHLLSEIDQM-ATQVGIVSKGTLIFQDSI 224


>dbj|BAA96370.1| (AB035331) ABC protein [Physarum polycephalum]
           Length = 325
           
 Score = 70.6 bits (170), Expect = 5e-11
 Identities = 66/243 (27%), Positives = 112/243 (45%), Gaps = 39/243 (16%)

Query: 407 ESELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLR 466
           ++ L  KGL +  +++  A+  R  VI   VL+ ++    PG+VVA+VG SG GK+T++ 
Sbjct: 72  DTPLQFKGLIR-YENVFFAYPSRPDVI---VLKGVDLECKPGQVVALVGPSGGGKSTMVA 127

Query: 467 LILGAIKGYWEEKYRPTSGKIEVPKNAKVSVLIPGEIEPEFG-------------SETIL 513
           L+        E  Y P SG + +     +  L P  +  + G             S+ I 
Sbjct: 128 LL--------EAFYYPVSGHLTI-DGVDIRDLDPEFLHDKVGLVSQEPTLFAASISDNIA 178

Query: 514 EHVYRKIRDLNAAVEVLNRAGLSDAV---------LYRAKFSELSTGQKERAKIASLLAE 564
             +  K   +++ +E    A   D +         L   +   LS GQK+R  IA  + +
Sbjct: 179 YGIKGKKVSIDSIIEAAKHANAHDFITSLPQGYDTLVGERGVRLSGGQKQRVAIARAVLK 238

Query: 565 RPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGY 624
            P +LL+DE  + LD  +   V + + E+++    T ++I HR   VK  +  KV+ V  
Sbjct: 239 DPTILLLDEATSALDAESEYLVKKALDELMQHR--TTLVIAHRLSTVK--NAHKVVVVES 294

Query: 625 GTV 627
           GT+
Sbjct: 295 GTI 297


>pir||DVHY1C multidrug resistance protein 1 - Chinese hamster
           >gi|191155|gb|AAA37004.1| (M59253) p-glycoprotein
           [Cricetulus sp.]
           Length = 1276
           
 Score = 70.2 bits (169), Expect = 6e-11
 Identities = 67/264 (25%), Positives = 116/264 (43%), Gaps = 59/264 (22%)

Query: 389 KVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPG 448
           K + ++G + FKN+   + S  D++                       +L+ LN  +  G
Sbjct: 381 KPDNIKGNLEFKNIHFSYPSRKDVQ-----------------------ILKGLNLKVQSG 417

Query: 449 EVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPK------NAKVSVLIPGE 502
           + VA+VG SG GK+T ++L+        +  Y PT G + +        N +    I G 
Sbjct: 418 QTVALVGNSGCGKSTTVQLL--------QRLYDPTEGVVSIDGQDIRTINVRYLREIIGV 469

Query: 503 IEPE-------------FGSETI-LEHVYRKIRDLNAAVEVLNRAGLSDAVLYRAKFSEL 548
           +  E             +G E + ++ + + +++ NA   ++      D  L   + ++L
Sbjct: 470 VSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDT-LVGERGAQL 528

Query: 549 STGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRP 608
           S GQK+R  IA  L   P +LL+DE  + LDT  +  V +   +  RE G T ++I HR 
Sbjct: 529 SGGQKQRIAIARALVRNPKILLLDEATSALDT-ESEAVVQAALDKARE-GRTTIVIAHRL 586

Query: 609 EVVKALDPDKVLFVGY-GTVIVRK 631
             V+  D    +  G+ G VIV +
Sbjct: 587 STVRNAD----IIAGFDGGVIVEQ 606


>sp|P21448|MDR1_CRIGR MULTIDRUG RESISTANCE PROTEIN 1 (P-GLYCOPROTEIN 1)
           >gi|191165|gb|AAA68883.1| (M60040) p-glycoprotein
           isoform I [Cricetulus griseus]
           Length = 1276
           
 Score = 70.2 bits (169), Expect = 6e-11
 Identities = 67/264 (25%), Positives = 116/264 (43%), Gaps = 59/264 (22%)

Query: 389 KVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPG 448
           K + ++G + FKN+   + S  D++                       +L+ LN  +  G
Sbjct: 381 KPDNIKGNLEFKNIHFSYPSRKDVQ-----------------------ILKGLNLKVQSG 417

Query: 449 EVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPK------NAKVSVLIPGE 502
           + VA+VG SG GK+T ++L+        +  Y PT G + +        N +    I G 
Sbjct: 418 QTVALVGNSGCGKSTTVQLL--------QRLYDPTEGVVSIDGQDIRTINVRYLREIIGV 469

Query: 503 IEPE-------------FGSETI-LEHVYRKIRDLNAAVEVLNRAGLSDAVLYRAKFSEL 548
           +  E             +G E + ++ + + +++ NA   ++      D  L   + ++L
Sbjct: 470 VSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDT-LVGERGAQL 528

Query: 549 STGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRP 608
           S GQK+R  IA  L   P +LL+DE  + LDT  +  V +   +  RE G T ++I HR 
Sbjct: 529 SGGQKQRIAIARALVRNPKILLLDEATSALDT-ESEAVVQAALDKARE-GRTTIVIAHRL 586

Query: 609 EVVKALDPDKVLFVGY-GTVIVRK 631
             V+  D    +  G+ G VIV +
Sbjct: 587 STVRNAD----IIAGFDGGVIVEQ 606


>gb|AAA37005.1| (M59254) p-glycoprotein [Cricetulus sp.]
           Length = 1169
           
 Score = 70.2 bits (169), Expect = 6e-11
 Identities = 67/264 (25%), Positives = 116/264 (43%), Gaps = 59/264 (22%)

Query: 389 KVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPG 448
           K + ++G + FKN+   + S  D++                       +L+ LN  +  G
Sbjct: 274 KPDNIKGNLEFKNIHFSYPSRKDVQ-----------------------ILKGLNLKVQSG 310

Query: 449 EVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPK------NAKVSVLIPGE 502
           + VA+VG SG GK+T ++L+        +  Y PT G + +        N +    I G 
Sbjct: 311 QTVALVGNSGCGKSTTVQLL--------QRLYDPTEGVVSIDGQDIRTINVRYLREIIGV 362

Query: 503 IEPE-------------FGSETI-LEHVYRKIRDLNAAVEVLNRAGLSDAVLYRAKFSEL 548
           +  E             +G E + ++ + + +++ NA   ++      D  L   + ++L
Sbjct: 363 VSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDT-LVGERGAQL 421

Query: 549 STGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRP 608
           S GQK+R  IA  L   P +LL+DE  + LDT  +  V +   +  RE G T ++I HR 
Sbjct: 422 SGGQKQRIAIARALVRNPKILLLDEATSALDT-ESEAVVQAALDKARE-GRTTIVIAHRL 479

Query: 609 EVVKALDPDKVLFVGY-GTVIVRK 631
             V+  D    +  G+ G VIV +
Sbjct: 480 STVRNAD----IIAGFDGGVIVEQ 499


>sp|P75790|YBIT_ECOLI HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN YBIT
           >gi|7445681|pir||D64819 probable ABC-type transport
           protein ybiT - Escherichia coli
           >gi|1787041|gb|AAC73907.1| (AE000184) putative
           ATP-binding component of a transport system [Escherichia
           coli K12] >gi|4062387|dbj|BAA35501.1| (D90719)
           Hypothetical protein HI0658 [Escherichia coli]
           >gi|4062394|dbj|BAA35508.1| (D90720) Hypothetical
           protein HI0658 [Escherichia coli]
           Length = 530
           
 Score = 70.2 bits (169), Expect = 6e-11
 Identities = 62/232 (26%), Positives = 112/232 (47%), Gaps = 34/232 (14%)

Query: 389 KVEMLEGPIV-FKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINP 447
           K    + P + F+   K+F + L+++GL +   +              P+ +NLN  +  
Sbjct: 298 KASSRQNPFIRFEQDKKLFRNALEVEGLTKGFDN-------------GPLFKNLNLLLEV 344

Query: 448 GEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVSVLIPGEIEPEF 507
           GE +AV+G +G GK+TLL+ ++G +        +P SG ++  +NA++      + E EF
Sbjct: 345 GEKLAVLGTNGVGKSTLLKTLVGDL--------QPDSGTVKWSENARIGYYAQ-DHEYEF 395

Query: 508 GSE-TILEHV---YRKIRDLNAAVEVLNRAGLS-DAVLYRAKFSELSTGQKERAKIASLL 562
            ++ T+ E +    ++  D  A   +L R   S D +   AK   LS G+K R     L+
Sbjct: 396 ENDLTVFEWMSQWKQEGDDEQAVRSILGRLLFSQDDIKKPAKV--LSGGEKGRMLFGKLM 453

Query: 563 AERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKAL 614
            ++PN+L++DE   HLD    M     ++  +     T + ++H  E V +L
Sbjct: 454 MQKPNILIMDEPTNHLD----MESIESLNMALELYQGTLIFVSHDREFVSSL 501


>gi|11497838 branched-chain amino acid ABC transporter, ATP-binding protein
           (braF-1) [Archaeoglobus fulgidus]
           >gi|7445740|pir||F69277 branched-chain amino acid ABC
           transporter, ATP-binding protein (braF-1) homolog -
           Archaeoglobus fulgidus >gi|2650419|gb|AAB91010.1|
           (AE001090) branched-chain amino acid ABC transporter,
           ATP-binding protein (braF-1) [Archaeoglobus fulgidus]
           Length = 281
           
 Score = 70.2 bits (169), Expect = 6e-11
 Identities = 66/237 (27%), Positives = 113/237 (46%), Gaps = 18/237 (7%)

Query: 405 VFESELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTL 464
           V+ S+     L + ++ +LK   V  R  +  VL  +N  I+  E V ++G +GAGKTTL
Sbjct: 38  VWISKAKYLNLAETVKSMLKVRNVHKRFGECSVLEGVNLEIDKSERVGIIGPNGAGKTTL 97

Query: 465 LRLILGAIK---GYWEEKYRPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEHVYRKIR 521
             +I G +K   G    + R  +G ++  + AK+ ++   +I   F + T+ +++     
Sbjct: 98  FNIITGFLKPDRGEIRFRSRDITG-LKPNQLAKMGIVRTFQIVKVFSNMTVEQNMLTVSD 156

Query: 522 DLNAAVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTL 581
           DL    + L   GL +     A  + LS G+  +  IA  LA  P +LL+DE  + L   
Sbjct: 157 DL----DYLREFGLWEKRHELA--ANLSYGELRKLSIALALAPNPKLLLLDEPFSGLSPK 210

Query: 582 TAMRVARKVSEIVREAGITAVIITHR-------PEVVKALDPDKVLFVGYGTVIVRK 631
            A  +A  + E +   G +  II HR        E V  L+  +++F G+   +VR+
Sbjct: 211 EARDLA-GIIESINHNGQSIAIIEHRLKDLFNVAERVVVLNSGRIIFEGHPEEVVRE 266


>pir||B71676 probable ABC transporter msbA2 - Rickettsia prowazekii
           >gi|3861232|emb|CAA15132.1| (AJ235272) PROBABLE
           TRANSPORT ATP-BINDING PROTEIN MSBA (msbA2) [Rickettsia
           prowazekii]
           Length = 576
           
 Score = 70.2 bits (169), Expect = 6e-11
 Identities = 61/216 (28%), Positives = 104/216 (47%), Gaps = 33/216 (15%)

Query: 437 VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVS 496
           V+ N++  IN  + V +VG SGAGK+TL++L+L          YR  +G I +  N  +S
Sbjct: 353 VINNMSLKINSNKFVGIVGRSGAGKSTLIQLLL--------RFYRQENGTILI-NNQDIS 403

Query: 497 VLIPGEI---------EPEFGSETILEHVY---RKIRD--LNAAVEVLN----RAGLSDA 538
            + P +I         E    S+TI  ++     K  D  +N  +++         L D 
Sbjct: 404 FVKPTDIRKFIAYVPQEASIFSDTIKSNIIFGNNKASDYEINEIIKITGIEEFSTKLHDG 463

Query: 539 VLYRA--KFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVRE 596
           +  +   K   LS GQK+R  IA  L  +P +LL+DE  + LDT++  ++   + +I++ 
Sbjct: 464 INTKIGEKGVRLSGGQKQRIAIARALLRKPKILLLDEAMSALDTMSEQKLLNAIKKIMK- 522

Query: 597 AGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKS 632
            G   + I HR   +++   D +L +  G V+   S
Sbjct: 523 -GNIIISIAHRISSIES--ADYILVIDKGGVVTEGS 555


>pir||T21266 hypothetical protein F22E10.1 - Caenorhabditis elegans
            >gi|3876291|emb|CAA91799.1| (Z67882) contains similarity
            to Pfam domain: PF00005 (ABC transporter), Score=427.5,
            E-value=3.8e-125, N=2; PF00664 (ABC transporter
            transmembrane region.), Score=255.6, E-value=2.1e-73,
            N=2~cDNA EST yk10e8.3 comes from this gene~cDNA EST
            yk10e8.5 come>
            Length = 1318
            
 Score = 70.2 bits (169), Expect = 6e-11
 Identities = 70/268 (26%), Positives = 130/268 (48%), Gaps = 41/268 (15%)

Query: 385  PSYGKVEMLEGPIVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRP---VLRNL 441
            P + K +   G ++FK + +  ++   ++G   EI+  +    V+    QRP   V+ +L
Sbjct: 1040 PEFVKAKTAAG-MLFKLIYRKSKTGDVMEGNNTEIRGNVLFESVKFSYPQRPMQPVMTDL 1098

Query: 442  NFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEVP---------KN 492
            +F+ + G+ VA+VG SG GK+T + ++        E  Y  + G + +           +
Sbjct: 1099 HFSAHSGQTVALVGPSGTGKSTCIAML--------ERFYDVSGGALRIDGQNIKSLSLHH 1150

Query: 493  AKVSVLIPGEIEPEFGSETILEHVYRKIRDLNA-----AVEVLNR--------AGLSDAV 539
             +  + + G+ EP   + TI E+V   ++D++      A+E+ N         AG+   V
Sbjct: 1151 LRTQMALVGQ-EPRLFAGTIKENVCFGLKDVSVEKVHQALELANASRFLANLPAGIDTEV 1209

Query: 540  LYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGI 599
                K  +LS GQK+R  IA  L   P +LL+DE  + LD+  + R  ++  +  RE G 
Sbjct: 1210 --GEKGGQLSGGQKQRIAIARALVRDPKILLLDEATSALDS-ESERAVQEALDRARE-GR 1265

Query: 600  TAVIITHRPEVVKALDPDKVLFVGYGTV 627
            T + I HR   ++  + D ++++ +G V
Sbjct: 1266 TCITIAHRLSSIQ--NSDLIVYIDHGMV 1291


>pir||E75302 ABC transporter, ATP-binding protein - Deinococcus radiodurans
           (strain R1) >gi|6460001|gb|AAF11747.1|AE002053_2
           (AE002053) ABC transporter, ATP-binding protein
           [Deinococcus radiodurans]
           Length = 248
           
 Score = 70.2 bits (169), Expect = 6e-11
 Identities = 64/200 (32%), Positives = 95/200 (47%), Gaps = 28/200 (14%)

Query: 441 LNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKIEV---PKNAKVSV 497
           LN  + PGE + VVG SG+GK+TLL L+ G +        RP  G+I +   P N     
Sbjct: 43  LNLHVEPGEFLCVVGPSGSGKSTLLSLLAGFL--------RPQQGEIRLGGDPVNGPHPA 94

Query: 498 LIPGEIEPE-FGSETILEHVYRKIRDLNAA------VEVLNRAGLSDAVLYRAKFSELST 550
           L   + E   F   T+  +V   ++ ++ A       + L   GLS     R    ELS 
Sbjct: 95  LTLVQQEAALFPWLTVGGNVAFGLKGVSGAEKAARVADALRLVGLSGYEARRPH--ELSG 152

Query: 551 GQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEV 610
           GQ++R  IA  LA RP +LL+DE  + LD  T   +A ++  I  +  +T V +TH+   
Sbjct: 153 GQRQRVSIARALAVRPGLLLLDEPFSALDHATRTTLADELLAIWWQQKVTVVFVTHQ--- 209

Query: 611 VKALDPDKVLFVGYGTVIVR 630
                 D+ L +G   V +R
Sbjct: 210 -----LDEALHLGQRVVALR 224


>emb|CAA57938.1| (X82612) ATM1 [Saccharomyces cerevisiae]
           Length = 694
           
 Score = 69.9 bits (168), Expect = 8e-11
 Identities = 68/254 (26%), Positives = 118/254 (45%), Gaps = 43/254 (16%)

Query: 400 KNVTKVFESELDI---KGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGA 456
           KN  K+  +E  +   + +P +I      FG       R +L+N +FTI  G   A+VG+
Sbjct: 418 KNEVKIKNAERPLMLPENVPYDITFENVTFGYHP---DRKILKNASFTIPAGWKTAIVGS 474

Query: 457 SGAGKTTLLRLILGAIKGYWEEKYRPTSGKI----------EVPKNAKVSVLIPGEIEPE 506
           SG+GK+T+L+L+           Y P SG+I          ++    KV  ++P +  P 
Sbjct: 475 SGSGKSTILKLVF--------RFYDPESGRILINGRDIKEYDIDALRKVIGVVPQD-TPL 525

Query: 507 FGSETILEHVYRKIRDLNA----AVEVLNRAGLSDAV---------LYRAKFSELSTGQK 553
           F ++TI E+V  K   ++A     + V+ +A L+  +         +   +   +S G+K
Sbjct: 526 F-NDTIWENV--KFGRIDATDEEVITVVEKAQLAPLIKKLPQGFDTIVGERGLMISGGEK 582

Query: 554 ERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKA 613
           +R  IA +L +   ++  DE  + LDT T   + R + +       T+V I HR   +  
Sbjct: 583 QRLAIARVLLKNARIMFFDEATSALDTHTEQALLRTIRDNFTSGSRTSVYIAHRLRTI-- 640

Query: 614 LDPDKVLFVGYGTV 627
            D DK++ +  G V
Sbjct: 641 ADADKIIVLDNGRV 654


>gi|6323959 mitochondrial ABC transporter protein; Atm1p [Saccharomyces
           cerevisiae] >gi|1352002|sp|P40416|ATM1_YEAST
           MITOCHONDRIAL TRANSPORTER ATM1 PRECURSOR
           >gi|1078103|pir||S54211 ATM1 protein precursor - yeast
           (Saccharomyces cerevisiae) >gi|793877|emb|CAA57359.1|
           (X81715) MDYp [Saccharomyces cerevisiae]
           >gi|798943|emb|CAA89134.1| (Z49212) Atm1p [Saccharomyces
           cerevisiae]
           Length = 690
           
 Score = 69.9 bits (168), Expect = 8e-11
 Identities = 68/254 (26%), Positives = 118/254 (45%), Gaps = 43/254 (16%)

Query: 400 KNVTKVFESELDI---KGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGA 456
           KN  K+  +E  +   + +P +I      FG       R +L+N +FTI  G   A+VG+
Sbjct: 414 KNEVKIKNAERPLMLPENVPYDITFENVTFGYHP---DRKILKNASFTIPAGWKTAIVGS 470

Query: 457 SGAGKTTLLRLILGAIKGYWEEKYRPTSGKI----------EVPKNAKVSVLIPGEIEPE 506
           SG+GK+T+L+L+           Y P SG+I          ++    KV  ++P +  P 
Sbjct: 471 SGSGKSTILKLVF--------RFYDPESGRILINGRDIKEYDIDALRKVIGVVPQD-TPL 521

Query: 507 FGSETILEHVYRKIRDLNA----AVEVLNRAGLSDAV---------LYRAKFSELSTGQK 553
           F ++TI E+V  K   ++A     + V+ +A L+  +         +   +   +S G+K
Sbjct: 522 F-NDTIWENV--KFGRIDATDEEVITVVEKAQLAPLIKKLPQGFDTIVGERGLMISGGEK 578

Query: 554 ERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEVVKA 613
           +R  IA +L +   ++  DE  + LDT T   + R + +       T+V I HR   +  
Sbjct: 579 QRLAIARVLLKNARIMFFDEATSALDTHTEQALLRTIRDNFTSGSRTSVYIAHRLRTI-- 636

Query: 614 LDPDKVLFVGYGTV 627
            D DK++ +  G V
Sbjct: 637 ADADKIIVLDNGRV 650


>gb|AAB63643.1| (AC001645) ABC transporter (PDR5-like) isolog [Arabidopsis thaliana]
            >gi|9279716|dbj|BAB01273.1| (AB023046) ABC transporter
            [Arabidopsis thaliana]
            Length = 1416
            
 Score = 69.9 bits (168), Expect = 8e-11
 Identities = 65/229 (28%), Positives = 103/229 (44%), Gaps = 27/229 (11%)

Query: 399  FKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASG 458
            F  +T  F++      +P+E    +K  GV    +Q  +L+ +     PG + A++G SG
Sbjct: 809  FTPLTMSFDNVNYYVDMPKE----MKEQGVSKDKLQ--LLKEVTGVFRPGVLTALMGVSG 862

Query: 459  AGKTTLLRLILGAIKGYWEEKYRPTSGKIEVPKNAKVSVLIPGEIEPE---FGSETILEH 515
            AGKTTL+ ++ G   G + E     SG    PK  +    I G  E         T+ E 
Sbjct: 863  AGKTTLMDVLAGRKTGGYIEGDIRISG---FPKRQETFARISGYCEQNDIHSPQVTVKES 919

Query: 516  V--------------YRKIRDLNAAVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASL 561
            +              Y K+R ++  +E++    L DAV+     + LST Q++R  IA  
Sbjct: 920  LIYSAFLRLPKEVTKYEKMRFVDEVMELVELESLKDAVVGLPGITGLSTEQRKRLTIAVE 979

Query: 562  LAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITHRPEV 610
            L   P+++ +DE  + LD   A  V R V   V + G T V   H+P +
Sbjct: 980  LVANPSIIFMDEPTSGLDARAAAIVMRTVRNTV-DTGRTVVCTIHQPSI 1027


>gb|AAC98048.1| (AC005896) putative ABC transporter [Arabidopsis thaliana]
            Length = 1413
            
 Score = 69.9 bits (168), Expect = 8e-11
 Identities = 81/304 (26%), Positives = 129/304 (41%), Gaps = 51/304 (16%)

Query: 333  YNPFFEKVGFKFVWETASGRPVLIYPLTQEAKEYLERYFKEDPYAPKEPLWKPSYGKVEM 392
            +N  F  +   F+    S RP++      E +   +   K++         KP    ++ 
Sbjct: 748  FNTIFT-LALSFLKSPTSSRPMISQDKLSELQGTKDSSVKKN---------KPLDSSIKT 797

Query: 393  LEGP----IVFKNVTKVFESELDIKGLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPG 448
             E P    + FK +T  F+       +P E    +K  G   + +Q  +L  +     PG
Sbjct: 798  NEDPGKMILPFKPLTITFQDLNYYVDVPVE----MKGQGYNEKKLQ--LLSEITGAFRPG 851

Query: 449  EVVAVVGASGAGKTTLLRLILGA-IKGYWEEKYRPTSGKIEVPKN-AKVS-------VLI 499
             + A++G SGAGKTTLL ++ G    GY E + R  SG ++V +  A+VS       +  
Sbjct: 852  VLTALMGISGAGKTTLLDVLAGRKTSGYIEGEIR-ISGFLKVQETFARVSGYCEQTDIHS 910

Query: 500  PG-------------EIEPEFGSETILEHVYRKIRDLNAAVEVLNRAGLSDAVLYRAKFS 546
            P               + PE   +T       KIR +   +E +    + DA++  A  S
Sbjct: 911  PSITVEESLIYSAWLRLVPEINPQT-------KIRFVKQVLETIELEEIKDALVGVAGVS 963

Query: 547  ELSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIVREAGITAVIITH 606
             LST Q++R  +A  L   P+++ +DE    LD   A  V R V   V E G T V   H
Sbjct: 964  GLSTEQRKRLTVAVELVANPSIIFMDEPTTGLDARAAAIVMRAVKN-VAETGRTIVCTIH 1022

Query: 607  RPEV 610
            +P +
Sbjct: 1023 QPSI 1026


>pir||G72598 probable ABC transporter ATP-binding protein APE1255 - Aeropyrum
           pernix (strain K1) >gi|5104931|dbj|BAA80245.1|
           (AP000061) 253aa long hypothetical ABC transporter
           ATP-binding protein [Aeropyrum pernix]
           Length = 253
           
 Score = 69.9 bits (168), Expect = 8e-11
 Identities = 61/215 (28%), Positives = 105/215 (48%), Gaps = 24/215 (11%)

Query: 414 GLPQEIQDLLKAFGVRHRVIQRPVLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIK 473
           GL    Q  ++A GV  R+  R VL++++ T+  G V  VVG +GAGKTTL R +LG   
Sbjct: 4   GLGGAGQPAVEAEGVWKRLGGRWVLKDVSLTVPRGSVYGVVGPNGAGKTTLFRTLLGL-- 61

Query: 474 GYWEEKYRPTSGKI----EVPKNAKVSVLIPGEIEPEFGS--ETILEHVYRK-------I 520
                 YR   G++    E  + A  S+       PE G     +  H + +       +
Sbjct: 62  ------YRADRGRVALLGEPVERAGGSLFRRVAYLPEDGEPYRNMTGHEFLRLYASIYGV 115

Query: 521 RDLNAAVEVLNR-AGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLD 579
            DL   +E  +R +GL   +  R +    S G + R  +A++LA +P++ ++DE  A LD
Sbjct: 116 EDLEGYLEEASRLSGLGGRLGERVR--SYSKGMRRRLLVAAMLALKPSLAVLDEPTAGLD 173

Query: 580 TLTAMRVARKVSEIVREAGITAVIITHRPEVVKAL 614
            + ++ + R + E     G+T ++ +H    V+++
Sbjct: 174 PVYSVGIRRLLKEYSERHGVTVLLSSHNMYEVESV 208


>gb|AAD47141.1|AF078777_1 (AF078777) ABC transporter [Homo sapiens]
           Length = 748
           
 Score = 69.9 bits (168), Expect = 8e-11
 Identities = 62/216 (28%), Positives = 107/216 (48%), Gaps = 37/216 (17%)

Query: 437 VLRNLNFTINPGEVVAVVGASGAGKTTLLRLILGAIKGYWEEKYRPTSGKI-----EVPK 491
           VL  ++F +  G+ VA+VG SG+GK+T++RL+           Y P  G I      +  
Sbjct: 483 VLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLF--------RFYEPQKGSIYLAGQNIQD 534

Query: 492 NAKVSVLIPGEIEPEFGSETILEH--VYRKI--RDLNAAVE----VLNRAGLSDAVL--- 540
            + VS+     + P+   + +L H  +Y  +   +++A+ E    V   AGL DA+L   
Sbjct: 535 VSLVSLRRAVGVVPQ---DAVLFHNTIYYNLLYGNISASPEEVYAVAKLAGLHDAILRMP 591

Query: 541 --YRAKFSE----LSTGQKERAKIASLLAERPNVLLIDEFAAHLDTLTAMRVARKVSEIV 594
             Y  +  E    LS G+K+R  IA  + + P V+L DE  + LD++T   +   + ++V
Sbjct: 592 HGYDTQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDVV 651

Query: 595 REAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVR 630
           +    T++ I HR   V  +D D+++ +  G V  R
Sbjct: 652 KHR--TSIFIAHRLSTV--VDADEIIVLDQGKVAER 683


>pir||D83419 probable ATP-binding component of ABC transporter PA1807 [imported]
           - Pseudomonas aeruginosa (strain PAO1)
           >gi|9947791|gb|AAG05196.1|AE004607_2 (AE004607) probable
           ATP-binding component of ABC transporter [Pseudomonas
           aeruginosa]
           Length = 536
           
 Score = 69.9 bits (168), Expect = 8e-11
 Identities = 65/233 (27%), Positives = 108/233 (45%), Gaps = 21/233 (9%)

Query: 419 IQDLLKAFGVRHRVIQRPV-----LRNLNFTINPGEVVAVVGASGAGKTTL----LRLI- 468
           + DL   F +R  V +R V     +  +NF +  G+ + +VG SG+GK+TL    LRL+ 
Sbjct: 277 VDDLRVWFPIRKGVFRRTVDHVKAVDGVNFELPRGQTLGIVGESGSGKSTLGLAILRLLE 336

Query: 469 -LGAIK-------GYWEEKYRPTSGKIEVPKNAKVSVLIPGEIEPEFGSETILEH-VYRK 519
             G I+       G  +   RP   +++V        L P     E   E +  H +  +
Sbjct: 337 SQGGIRFEGTRLDGLAQHDVRPLRREMQVVFQDPYGSLSPRMCVGEIVGEGLRIHRIGSE 396

Query: 520 IRDLNAAVEVLNRAGLSDAVLYRAKFSELSTGQKERAKIASLLAERPNVLLIDEFAAHLD 579
                A ++ L   GL     YR    E S GQ++R  IA  L  +P ++L+DE  + LD
Sbjct: 397 AEQEQAIIDALVEVGLDPQTRYRYPH-EFSGGQRQRIAIARALVLKPALILLDEPTSALD 455

Query: 580 TLTAMRVARKVSEIVREAGITAVIITHRPEVVKALDPDKVLFVGYGTVIVRKS 632
                +V   + ++  +  +T + I+H   VVKAL   +++ V +G V+ + S
Sbjct: 456 RTVQRQVVELLRQLQGKYNLTYLFISHDLAVVKALS-HQLMVVRHGKVVEQGS 507


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.319    0.138    0.405 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 236841823
Number of Sequences: 2977
Number of extensions: 10347079
Number of successful extensions: 42123
Number of sequences better than 1.0e-10: 287
Number of HSP's better than  0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 284
Number of HSP's that attempted gapping in prelim test: 41660
Number of HSP's gapped (non-prelim): 434
length of query: 633
length of database: 189,106,746
effective HSP length: 57
effective length of query: 576
effective length of database: 154,992,987
effective search space: 89275960512
effective search space used: 89275960512
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 168 (69.9 bits)