BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1930 (thiC) DE:thiamine biosynthesis protein THIC
(429 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||E75107 thiamin biosynthesis protein thic PAB1930 - Pyrococc... 864 0.0
gi|11499988 thiamine biosynthesis protein (thiC) [Archaeoglobus ... 504 e-142
sp|Q58432|THIC_METJA PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THIC... 495 e-139
sp|O27617|THC2_METTH PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THIC... 458 e-128
sp|Q9WZP5|THIC_THEMA THIAMINE BIOSYNTHESIS PROTEIN THIC >gi|7448... 434 e-120
sp|O27586|THC1_METTH PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THIC... 432 e-120
gb|AAK42135.1| Thiamine biosynthesis protein (thiC-2) [Sulfolobu... 405 e-112
gb|AAK41561.1| Thiamine biosynthesis protein (thiC-1) [Sulfolobu... 400 e-110
sp|Q55894|THIC_SYNY3 THIAMINE BIOSYNTHESIS PROTEIN THIC >gi|7448... 400 e-110
sp|O67259|THIC_AQUAE THIAMINE BIOSYNTHESIS PROTEIN THIC >gi|7448... 385 e-106
pir||H81389 thiamin biosynthesis protein ThiC Cj0453 [imported] ... 374 e-102
gb|AAG19196.1| (AE005016) thiamine biosynthesis protein; ThiC [H... 367 e-100
dbj|BAB05652.1| (AP001513) thiamin biosynthesis protein [Bacillu... 346 3e-94
sp|P45740|THIC_BACSU THIAMINE BIOSYNTHESIS PROTEIN THIC >gi|7448... 344 1e-93
sp|Q9X9U0|THIC_STRCO THIAMINE BIOSYNTHESIS PROTEIN THIC >gi|7481... 344 2e-93
sp|P96269|THIC_MYCTU THIAMINE BIOSYNTHESIS PROTEIN THIC >gi|7448... 343 3e-93
sp|Q9ZBL0|THIC_MYCLE THIAMINE BIOSYNTHESIS PROTEIN THIC >gi|1127... 336 3e-91
gb|AAA68243.1| (U26178) thiA gene product [Bacillus subtilis] 335 4e-91
gb|AAC35232.1| (AC005496) putative thiamin biosynthesis protein ... 335 4e-91
pir||C83024 thiamin biosynthesis protein ThiC PA4973 [imported] ... 326 2e-88
pir||B75614 thiamin biosynthesis protein thiC DRA0175 [similarit... 323 3e-87
pir||E82624 thiamin biosynthesis protein XF1888 [imported] - Xyl... 321 1e-86
pir||H82368 thiamin biosynthesis protein ThiC VC0061 [imported] ... 318 6e-86
pir||C81956 thiamin biosynthesis protein NMA0397 [imported] - Ne... 317 1e-85
pir||E81012 thiamin biosynthesis protein ThiC NMB2040 [imported]... 317 2e-85
gb|AAF33523.1| (AF170176) 93% identity over 631 amino acids with... 316 4e-85
sp|P30136|THIC_ECOLI THIAMINE BIOSYNTHESIS PROTEIN THIC >gi|7430... 315 6e-85
pir||S35117 thiC protein - Escherichia coli >gi|414232|gb|AAB956... 315 6e-85
sp|O34291|THIC_RHIET THIAMINE BIOSYNTHESIS PROTEIN THIC >gi|1127... 307 2e-82
>pir||E75107 thiamin biosynthesis protein thic PAB1930 - Pyrococcus abyssi
(strain Orsay) >gi|5458085|emb|CAB49574.1| (AJ248285)
thiamine biosynthesis protein THIC [Pyrococcus abyssi]
Length = 429
Score = 864 bits (2208), Expect = 0.0
Identities = 429/429 (100%), Positives = 429/429 (100%)
Query: 1 MTQMEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVR 60
MTQMEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVR
Sbjct: 1 MTQMEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVR 60
Query: 61 VKVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGT 120
VKVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGT
Sbjct: 61 VKVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGT 120
Query: 121 VPIYQAAEEMLAKGKAIIEMTEDDMWRAIEKHFKDGVDFATVHVGVTKEVVEKMKRIKRV 180
VPIYQAAEEMLAKGKAIIEMTEDDMWRAIEKHFKDGVDFATVHVGVTKEVVEKMKRIKRV
Sbjct: 121 VPIYQAAEEMLAKGKAIIEMTEDDMWRAIEKHFKDGVDFATVHVGVTKEVVEKMKRIKRV 180
Query: 181 VGMVSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDEL 240
VGMVSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDEL
Sbjct: 181 VGMVSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDEL 240
Query: 241 QIAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGPLVTD 300
QIAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGPLVTD
Sbjct: 241 QIAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGPLVTD 300
Query: 301 IFPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAVNLLR 360
IFPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAVNLLR
Sbjct: 301 IFPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAVNLLR 360
Query: 361 FEDEYRKDYEMSLARGNLNWARQFEIAFDKDKFIEIRKERPTKTEACSMCGDLCAIKIIQ 420
FEDEYRKDYEMSLARGNLNWARQFEIAFDKDKFIEIRKERPTKTEACSMCGDLCAIKIIQ
Sbjct: 361 FEDEYRKDYEMSLARGNLNWARQFEIAFDKDKFIEIRKERPTKTEACSMCGDLCAIKIIQ 420
Query: 421 EMLTKKQTS 429
EMLTKKQTS
Sbjct: 421 EMLTKKQTS 429
>gi|11499988 thiamine biosynthesis protein (thiC) [Archaeoglobus fulgidus]
>gi|7388298|sp|O30259|THIC_ARCFU PROBABLE THIAMINE
BIOSYNTHESIS PROTEIN THIC >gi|7448744|pir||E69551
thiamin biosynthesis protein thiC AF2412 - Archaeoglobus
fulgidus >gi|2650682|gb|AAB91254.1| (AE001109) thiamine
biosynthesis protein (thiC) [Archaeoglobus fulgidus]
Length = 425
Score = 504 bits (1284), Expect = e-142
Identities = 246/424 (58%), Positives = 316/424 (74%), Gaps = 7/424 (1%)
Query: 1 MTQMEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVR 60
MT +EDA+KGV+TD + A EGI +KL +L++ GY V+ +N + V+P A+G
Sbjct: 1 MTLIEDARKGVVTDFVKKAAEYEGIEAEKLIRLISHGYVVLPKNVRREEVQPRAIGMLTS 60
Query: 61 VKVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGT 120
KVNAN+GTS D INVEEE+EKA +A K GAD +MDLS+GGDLD IR++IM+ V+VP GT
Sbjct: 61 TKVNANVGTSADYINVEEEVEKAIIAQKAGADAVMDLSSGGDLDAIRKRIMEVVEVPFGT 120
Query: 121 VPIYQAAEEMLAKGKAIIEMTEDDMWRAIEKHFKDGVDFATVHVGVTKEVVEKMKRIKRV 180
VPIYQAA + +++M EDD +R +EKH KDGVDF T+H GV VE+++R KR+
Sbjct: 121 VPIYQAARDC----HRVVDMDEDDFFRVVEKHAKDGVDFMTIHAGVNWVSVERLRRSKRL 176
Query: 181 VGMVSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDEL 240
+G+VSRGG W+LH +ENP YKD+DYLLE+ KEYDV +SLGD RPG + DAGD
Sbjct: 177 LGVVSRGGAITIGWMLHNEKENPYYKDFDYLLEILKEYDVTISLGDAYRPGCIHDAGDRA 236
Query: 241 QIAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGPLVTD 300
+ E LG LV++ R+ GVQ MVEGPGHVP+DQI ++ MK TDNAP+Y+LGPLVTD
Sbjct: 237 KYTEFIMLGELVEKCREKGVQCMVEGPGHVPLDQIETSVRAMKSVTDNAPLYLLGPLVTD 296
Query: 301 IFPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAVNLLR 360
I GYDHIA AIG AIA + GADF+CYVTP+EHL LP VE VREGVIAAK+AAHA++L++
Sbjct: 297 IAAGYDHIAAAIGAAIAGMAGADFICYVTPSEHLALPTVEDVREGVIAAKIAAHAIDLIK 356
Query: 361 ---FEDEYRKDYEMSLARGNLNWARQFEIAFDKDKFIEIRKERPTKTEACSMCGDLCAIK 417
E ++DYEMSLAR NL+W RQFE++ D +K EI R +++EACSMCGDLCAIK
Sbjct: 357 EGQRERARQRDYEMSLARKNLDWERQFELSIDPEKAREIYSRRKSESEACSMCGDLCAIK 416
Query: 418 IIQE 421
+++E
Sbjct: 417 LVKE 420
>sp|Q58432|THIC_METJA PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THIC >gi|2129301|pir||A64428
thiamin biosynthesis protein thiC MJ1026 - Methanococcus
jannaschii >gi|1591682|gb|AAB99030.1| (U67545) thiamine
biosynthesis protein (thiC) [Methanococcus jannaschii]
Length = 438
Score = 495 bits (1261), Expect = e-139
Identities = 243/424 (57%), Positives = 319/424 (74%), Gaps = 3/424 (0%)
Query: 1 MTQMEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVR 60
MTQM+DAK G+IT+EM +A +E I +KLRKL+AKGY VI +N D PV +G +R
Sbjct: 13 MTQMDDAKNGIITEEMKIVAEKEKIDIEKLRKLIAKGYVVILKNVNRD-TNPVGIGQSLR 71
Query: 61 VKVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGT 120
KVNANIGTS D +++E EI+KAK+A KYGAD +MDLSTGG+L+EIR+ IM AV +PIGT
Sbjct: 72 TKVNANIGTSPDCVDIELEIKKAKIAEKYGADAVMDLSTGGNLEEIRKAIMDAVKIPIGT 131
Query: 121 VPIYQAAEEMLAKGKAIIEMTEDDMWRAIEKHFKDGVDFATVHVGVTKEVVEKMKRIKRV 180
VPIY+ + K +I+M ED M++ IEK K+GVDF T+H G+TK+ VE++KR R+
Sbjct: 132 VPIYEVGKLAREKYGRVIDMNEDLMFKVIEKQAKEGVDFMTLHCGITKQSVERLKRSGRI 191
Query: 181 VGMVSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDEL 240
+G+VSRGG FL A+IL+ N+ENPLYK++DYLL++ KE+DV +SLGDG+RPG L D D
Sbjct: 192 MGVVSRGGAFLTAYILYHNEENPLYKNFDYLLDILKEHDVTISLGDGMRPGCLADNTDRA 251
Query: 241 QIAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGPLVTD 300
QI EL TLG LV+R R+ GVQ MVEGPGH+PI+ I I+L K NAP YVLGP+VTD
Sbjct: 252 QIEELITLGELVERCREKGVQCMVEGPGHIPINYIETNIRLQKSLCKNAPFYVLGPIVTD 311
Query: 301 IFPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAVNLLR 360
I PGYDHI AIGGA+A GADFLCYVTP+EHL LP +E V+EGVIA K+AA A ++ +
Sbjct: 312 IAPGYDHITAAIGGALAGYYGADFLCYVTPSEHLRLPTIEDVKEGVIATKIAAQAADVAK 371
Query: 361 FED-EYRKDYEMSLARGNLNWARQFEIAFDKDKFIEIRKERPTKTE-ACSMCGDLCAIKI 418
+ K+ EM+ AR N +W +QFE+A DK+K ++R+E P+K E ACS+CGD CA+ +
Sbjct: 372 GNKLAWEKETEMAYARKNHDWEKQFELAIDKEKARKMREEIPSKEEKACSICGDYCALLM 431
Query: 419 IQEM 422
++E+
Sbjct: 432 VEEL 435
>sp|O27617|THC2_METTH PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THIC 2
>gi|7448743|pir||C69077 thiamin biosynthesis protein
thiC MTH1576 - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2622698|gb|AAB86049.1| (AE000917)
thiamine biosynthesis protein [Methanobacterium
thermoautotrophicum]
Length = 424
Score = 458 bits (1165), Expect = e-128
Identities = 229/423 (54%), Positives = 306/423 (72%), Gaps = 3/423 (0%)
Query: 1 MTQMEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVR 60
MTQME+A+KG IT EM +A +E + L + +A G VI N ++ P +G +
Sbjct: 1 MTQMEEARKGNITPEMEEVARKENLDIQMLIRGIANGRIVIPSN-INRESSPCGIGENLS 59
Query: 61 VKVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGT 120
K+NANIG+S + ++E E++KA AV+YGAD +MDLSTG L ++R+ +++AVDVP+GT
Sbjct: 60 TKINANIGSSSKMEDIELEVDKALAAVEYGADAVMDLSTGPMLRDVRKAVLEAVDVPVGT 119
Query: 121 VPIYQAAEEMLAKGKAIIEMTEDDMWRAIEKHFKDGVDFATVHVGVTKEVVEKMKRIKRV 180
VPIY+A E A+++M EDDM+RAIE +DGVDF TVH G+T E VE+ +R R+
Sbjct: 120 VPIYEAGVEAFMSDGAVVDMDEDDMFRAIENQARDGVDFMTVHSGITLETVERAQRSGRI 179
Query: 181 VGMVSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDEL 240
+G+VSRGG FLAAWI+ +ENPLY +Y+YLLE+A EYDV LSLGDGLRPG L DA D
Sbjct: 180 MGIVSRGGAFLAAWIMQNQEENPLYSNYEYLLEVAYEYDVTLSLGDGLRPGCLADASDIP 239
Query: 241 QIAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGPLVTD 300
QI+EL TL LV+RAR A VQ MVEGPGH+P+DQI A +K+ K D AP YVLGP+VTD
Sbjct: 240 QISELLTLAELVERARDADVQCMVEGPGHMPLDQIAANMKIQKEVCDGAPFYVLGPIVTD 299
Query: 301 IFPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAVNLLR 360
+ PGYDHI+ AIGGA+AA+NGADFLCYVTPAEHL +P V+ V EGVIA+++AA A + R
Sbjct: 300 MAPGYDHISAAIGGAVAAMNGADFLCYVTPAEHLAIPGVQDVIEGVIASRIAAQAADAAR 359
Query: 361 -FEDEYRKDYEMSLARGNLNWARQFEIAFDKDKFIEIRKERPTK-TEACSMCGDLCAIKI 418
+ + EM+ AR + +W +QF++AFD K E R + P + +E CSMCG+ CA++I
Sbjct: 360 KLPGAWDSELEMADARRSFDWDKQFKLAFDSKKPYEYRMQCPIEDSEMCSMCGEYCALRI 419
Query: 419 IQE 421
++E
Sbjct: 420 LRE 422
>sp|Q9WZP5|THIC_THEMA THIAMINE BIOSYNTHESIS PROTEIN THIC >gi|7448747|pir||E72333 thiamin
biosynthesis protein thiC TM0788 [similarity] -
Thermotoga maritima (strain MSB8)
>gi|4981317|gb|AAD35870.1|AE001747_13 (AE001747)
thiamine biosynthesis protein, putative [Thermotoga
maritima]
Length = 424
Score = 434 bits (1104), Expect = e-120
Identities = 210/422 (49%), Positives = 301/422 (70%), Gaps = 1/422 (0%)
Query: 1 MTQMEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVR 60
MTQME A+KGV++DEM +A EG+ + +R+ +A+G V+ +NK+H +P+ VG G
Sbjct: 1 MTQMEMARKGVVSDEMKKVAEYEGVDVEIVRQKLAEGRAVLPKNKLHRIERPMIVGEGFS 60
Query: 61 VKVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGT 120
VKVNANIGTS+ ++EEE EKA+VA++YGAD++M LST GDL EIRR I++ VP+G+
Sbjct: 61 VKVNANIGTSQGFSSLEEEKEKARVAIEYGADSLMVLSTWGDLREIRRAIVEMSPVPVGS 120
Query: 121 VPIYQAAEEMLAKGKAIIEMTEDDMWRAIEKHFKDGVDFATVHVGVTKEVVEKMKRIKRV 180
VPIY +A K +++ +E D + + H +DG+DF T+HVGVT+ V++++K +RV
Sbjct: 121 VPIYDSAVRSYQMKKNVVDFSEKDFFDMVIAHAEDGIDFMTIHVGVTRRVLDRIKSSRRV 180
Query: 181 VGMVSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDEL 240
+ +VSRGG +A W++ N+ENP Y+ +D LL++AK+YD+ LSLGDG+RPG + DA D
Sbjct: 181 LKIVSRGGAIIAGWMIKNNKENPFYEHFDELLDIAKDYDITLSLGDGMRPGAVVDASDAQ 240
Query: 241 QIAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGPLVTD 300
Q EL+ +G LV+RAR+ GVQ M+EGPGHVP++++ ++LMK AP+++LGPL TD
Sbjct: 241 QFEELFVMGELVERAREKGVQVMLEGPGHVPLNEVEMNVRLMKKIGKGAPIFLLGPLPTD 300
Query: 301 IFPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAVNLLR 360
GYDHIA AIGGA+A GADFLCYVTP+EH+ LP+VE VREGVIA+K+AA ++ R
Sbjct: 301 RAMGYDHIACAIGGALAGYYGADFLCYVTPSEHISLPDVEDVREGVIASKIAAIVADVAR 360
Query: 361 FEDE-YRKDYEMSLARGNLNWARQFEIAFDKDKFIEIRKERPTKTEACSMCGDLCAIKII 419
+ + + +M+LAR N +W F ++ KD + +ERP + CSMCG CAIKI
Sbjct: 361 GNKKAWELEKKMALARKNFDWETMFSLSLGKDVAKKKYEERPYPDKGCSMCGPFCAIKIA 420
Query: 420 QE 421
+E
Sbjct: 421 EE 422
>sp|O27586|THC1_METTH PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THIC 1
>gi|7448745|pir||H69072 thiamin biosynthesis protein
thiC MTH1543 - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2622663|gb|AAB86017.1| (AE000914)
thiamine biosynthesis protein [Methanobacterium
thermoautotrophicum]
Length = 433
Score = 432 bits (1100), Expect = e-120
Identities = 213/429 (49%), Positives = 297/429 (68%), Gaps = 1/429 (0%)
Query: 1 MTQMEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVR 60
MTQM++AKKGVITDEM +A E ++P+ +R+ VA G I N + V V +G+G+R
Sbjct: 1 MTQMDEAKKGVITDEMKAVAEAENVTPEFVRRGVASGKIAIPSNLNREEVAAVGIGAGLR 60
Query: 61 VKVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGT 120
KVNA IGTS DI++ + E EKA++A++ ADT+M+LS GGDLDEIRR+I+ +P+G+
Sbjct: 61 TKVNATIGTSTDIVDFDMEEEKARIAIENRADTLMELSVGGDLDEIRRRILDLSPIPVGS 120
Query: 121 VPIYQAAEEMLAKGKAIIEMTEDDMWRAIEKHFKDGVDFATVHVGVTKEVVEKMKRIKRV 180
VP+YQAA E + + A I M ED M+RAIEK KDG+DF +H V +E + ++KR R
Sbjct: 121 VPVYQAAIETIREKGASIYMDEDVMFRAIEKQAKDGIDFMAIHCSVNRETLRRLKRQGRE 180
Query: 181 VGMVSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDEL 240
G+VSRGG F++AW++ ENPLY+++DY+LE+AKE+D VLS+ + +R G + D+ D
Sbjct: 181 GGLVSRGGAFVSAWMVENGLENPLYENFDYILEIAKEHDFVLSMANAMRAGAIADSTDRA 240
Query: 241 QIAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGPLVTD 300
Q+ EL LG L+ RAR+AGVQT+VEGPGH+P+++I A + L K AP Y+LGP+VTD
Sbjct: 241 QVQELIVLGELIDRAREAGVQTIVEGPGHIPLNEIKANVILQKKLCRGAPFYMLGPIVTD 300
Query: 301 IFPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAVNLLR 360
I GYDHI +IG A +A GADF+CYVTPAEHL LP + V+EGVIA ++ A+ ++++
Sbjct: 301 IGAGYDHIVSSIGAAASAAAGADFICYVTPAEHLALPYPDDVKEGVIATRIGAYVGDMVK 360
Query: 361 FEDEYRKDYEMSLARGNLNWARQFEIAFDKDKFIEIRKERPTK-TEACSMCGDLCAIKII 419
KD EM+ AR LNW QF+ A + IR ERP + + C+MCG+ CA+KI+
Sbjct: 361 GIHNGEKDLEMANARKKLNWEAQFDAAMCPAEARRIRDERPPEDPDTCTMCGEYCAVKIV 420
Query: 420 QEMLTKKQT 428
E L T
Sbjct: 421 NEWLDSADT 429
>gb|AAK42135.1| Thiamine biosynthesis protein (thiC-2) [Sulfolobus solfataricus]
Length = 433
Score = 405 bits (1029), Expect = e-112
Identities = 203/424 (47%), Positives = 281/424 (65%), Gaps = 3/424 (0%)
Query: 4 MEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVRVKV 63
+++AK+G ITDEM I+ EGI +K+R +++G ++ RN + K V +G G+ KV
Sbjct: 4 IDEAKRGQITDEMRAISKLEGIPVEKVRNRISEGKIMLIRNAKYPSRKLVPIGKGLTTKV 63
Query: 64 NANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGTVPI 123
N NIGTS ++++++ E++K KVA K+G DT+MDLSTGGDLD IRR I+KA D+P+GTVP+
Sbjct: 64 NVNIGTSSEVVDLDMELQKVKVANKWG-DTLMDLSTGGDLDAIRRDIIKASDLPVGTVPV 122
Query: 124 YQAAEEMLAKGKAIIEMTEDDMWRAIEKHFKDGVDFATVHVGVTKEVVEKMKRIKRVVGM 183
YQ E K TED++ +EKH KDGV F T+H G+TK++ + + R++ +
Sbjct: 123 YQIFIESFKKKSGGAYFTEDELLNTVEKHLKDGVAFMTIHAGITKDLAIRALKSDRIIPI 182
Query: 184 VSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDELQIA 243
VSRGG +A W++H N ENP K++DY+LE+ KEYD V+SLGD LRPG DA DE QI
Sbjct: 183 VSRGGDMIAGWMIHNNSENPYRKNWDYVLEMFKEYDAVISLGDALRPGATGDAHDEFQIG 242
Query: 244 ELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGPLVTDIFP 303
EL RLVK A + GVQ MVEGPGHVP+++I +KLMK T P YVLGPL D+
Sbjct: 243 ELLETARLVKSALQKGVQVMVEGPGHVPLNEIAWDVKLMKKLTGGVPYYVLGPLPIDVGA 302
Query: 304 GYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAVNLLRFED 363
YDHIA AIG AI++ +G D LCY+TPAEHLGLP V+ V EG IA ++AAHA ++++
Sbjct: 303 PYDHIASAIGAAISSASGVDLLCYLTPAEHLGLPTVKQVEEGAIAYRIAAHAGDVVKLGR 362
Query: 364 EYRK-DYEMSLARGNLNWARQFEIAFDKDKFIEIRKERPT-KTEACSMCGDLCAIKIIQE 421
+ RK D E+S RG L+W D + ++ + T K +AC+MCG C + +
Sbjct: 363 KARKWDDEVSYYRGKLDWENMISKLIDPQRAYQVYTQFGTPKVKACTMCGGYCPMMWAMD 422
Query: 422 MLTK 425
+ K
Sbjct: 423 QVRK 426
>gb|AAK41561.1| Thiamine biosynthesis protein (thiC-1) [Sulfolobus solfataricus]
Length = 433
Score = 400 bits (1018), Expect = e-110
Identities = 203/427 (47%), Positives = 277/427 (64%), Gaps = 3/427 (0%)
Query: 1 MTQMEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVR 60
M +E+A+ G ITDEM I+ EGI +K+R +++ ++ RN + K V +G G+
Sbjct: 1 MAIIEEARSGQITDEMKEISKLEGIPVEKVRNRISECKIILIRNAKYPSKKLVPIGKGLT 60
Query: 61 VKVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGT 120
KVN NIGTS +++N++ E+EK KVA ++G DT+MDLSTGGDLD+IRR+I++A ++P+GT
Sbjct: 61 TKVNINIGTSDEVVNLQMELEKVKVANRWG-DTLMDLSTGGDLDDIRREIIRASELPVGT 119
Query: 121 VPIYQAAEEMLAKGKAIIEMTEDDMWRAIEKHFKDGVDFATVHVGVTKEVVEKMKRIKRV 180
VP+YQ E K TED++ +EKH KDGV F T+H G+TKE+ + + R+
Sbjct: 120 VPVYQVFIESFKKKSGGAYFTEDELLSTVEKHLKDGVAFMTIHAGITKELAIRALKSNRI 179
Query: 181 VGMVSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDEL 240
+ +VSRGG +A W++H N ENP K + YLLE+ KEYD V+SLGD LRPG DA DE
Sbjct: 180 IPIVSRGGDMIAGWMIHNNSENPYRKHWGYLLEMFKEYDAVISLGDALRPGATGDAHDEF 239
Query: 241 QIAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGPLVTD 300
Q+ EL RLVK A K GVQ MVEGPGHVP+++I +KLMK T P YVLGPL D
Sbjct: 240 QVGELLETARLVKSALKEGVQVMVEGPGHVPLNEIAWDVKLMKKLTGGVPYYVLGPLPID 299
Query: 301 IFPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAVNLLR 360
+ YDHIA AIG AI++ GAD LCY+TPAEHLGLP V+ V EG IA ++AAHA ++++
Sbjct: 300 VGAPYDHIASAIGAAISSAAGADLLCYLTPAEHLGLPTVKQVEEGAIAYRIAAHAGDVVK 359
Query: 361 FEDEYRK-DYEMSLARGNLNWARQFEIAFDKDKFIEIRKE-RPTKTEACSMCGDLCAIKI 418
RK D E+S RG L W D + ++ + K +AC+MCG C +
Sbjct: 360 LGRRVRKWDDEVSYYRGKLEWDNMISRLIDPQRAYQVYTQFGIPKVKACTMCGGYCPMMW 419
Query: 419 IQEMLTK 425
+ + K
Sbjct: 420 AMDQVRK 426
>sp|Q55894|THIC_SYNY3 THIAMINE BIOSYNTHESIS PROTEIN THIC >gi|7448742|pir||S76712 thiamin
biosynthesis protein thiC slr0118 [similarity] -
Synechocystis sp. (strain PCC 6803)
>gi|1208488|dbj|BAA10656.1| (D64004) ThiC protein
[Synechocystis sp.]
Length = 459
Score = 400 bits (1016), Expect = e-110
Identities = 218/433 (50%), Positives = 284/433 (65%), Gaps = 15/433 (3%)
Query: 1 MTQMEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVR 60
++QM A+KGVIT+EM Y+A RE + + ++ VA+G +I N H ++P+A+G +
Sbjct: 15 VSQMHYARKGVITEEMDYVAKRENLPVELIKDEVARGRMIIPANINHTNLEPMAIGIASK 74
Query: 61 VKVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGG-DLDEIRRKIMKAVDVPIG 119
KVNANIG S + N++EE+EK ++VKYGADT+MDLSTGG DLD IR I+ A VPIG
Sbjct: 75 CKVNANIGASPNSSNIDEEVEKLLLSVKYGADTVMDLSTGGGDLDVIRTAIINASPVPIG 134
Query: 120 TVPIYQAAEEMLAKGKAIIEMTEDDMWRAIEKHFKDGVDFATVHVGVTKEVVEKMKRIKR 179
TVPIYQA E + +I +T DD IEKH + GVD+ T+H G+ E + +K R
Sbjct: 135 TVPIYQALESVHG---SIENLTPDDFLHIIEKHAQQGVDYMTIHAGLLIEYLPLVK--SR 189
Query: 180 VVGMVSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDE 239
+ G+VSRGG +A W+LH +++NPLY +D ++E+ K+YDV SLGD LRPG DA D+
Sbjct: 190 ITGIVSRGGGIIAKWMLHHHKQNPLYTHFDEIIEIFKKYDVSFSLGDSLRPGCTHDASDD 249
Query: 240 LQIAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGPLVT 299
Q++EL TLG+L +RA + VQ MVEGPGHVPIDQI +K AP YVLGPLVT
Sbjct: 250 AQLSELKTLGQLTRRAWEHDVQVMVEGPGHVPIDQIEFNVKKQMEECSEAPFYVLGPLVT 309
Query: 300 DIFPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAVNLL 359
DI PGYDHI AIG AIA +G LCYVTP EHLGLPN E VR G+IA K+AAHA ++
Sbjct: 310 DIAPGYDHITSAIGAAIAGWHGTAMLCYVTPKEHLGLPNAEDVRNGLIAYKIAAHAADIA 369
Query: 360 RFEDEYR-KDYEMSLARGNLNWARQFEIAFDKDKFIEIRKER-----PTKTEACSMCG-D 412
R R +D E+S AR N +W RQFE++ D ++ E E E CSMCG
Sbjct: 370 RHRPGARDRDDELSKARYNFDWNRQFELSLDPERAKEYHDETLPADIYKTAEFCSMCGPK 429
Query: 413 LCAI--KIIQEML 423
C + K+ EML
Sbjct: 430 FCPMQTKVDAEML 442
>sp|O67259|THIC_AQUAE THIAMINE BIOSYNTHESIS PROTEIN THIC >gi|7448746|pir||H70403 thiamin
biosynthesis protein thiC aq_1204 - Aquifex aeolicus
>gi|2983647|gb|AAC07214.1| (AE000728) thiamine
biosynthesis protein [Aquifex aeolicus]
Length = 457
Score = 385 bits (978), Expect = e-106
Identities = 208/431 (48%), Positives = 286/431 (66%), Gaps = 12/431 (2%)
Query: 2 TQMEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVRV 61
TQM A++G+IT+EM Y+A REG+ P+ +R+ VA+G +I N H ++P+ +G +V
Sbjct: 17 TQMHLARQGIITEEMEYVAKREGLHPEFVRQEVARGRMIIPANINHLHLEPMCIGINSKV 76
Query: 62 KVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGTV 121
KVNANIG S ++ E+EKAKVA+KYGADTIMDLSTG + E R I+ VP+GTV
Sbjct: 77 KVNANIGNSGLASDIPTEVEKAKVAIKYGADTIMDLSTGEAIKETREAIINVSTVPVGTV 136
Query: 122 PIYQAAEEMLAKGKAIIEMTEDDMWRAIEKHFKDGVDFATVHVGVTKEVVEKMKRIKRVV 181
PIY+A + +AKG + E+T D + IE+ + GV + T+H G+ +E + ++ RV+
Sbjct: 137 PIYEAWK--IAKGN-VKELTVDLILDVIEEQARQGVSYMTIHAGILREHLPLVQH--RVM 191
Query: 182 GMVSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDELQ 241
G+VSRGG LA W+ ++NPLY+ +D + E+ K+YDV SLGD LRPG + DA D+ Q
Sbjct: 192 GIVSRGGAILAQWMAEHGKQNPLYEHFDKICEIFKKYDVSFSLGDALRPGCIEDATDDAQ 251
Query: 242 IAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGPLVTDI 301
+AEL LG LV++A K VQ MVEGPGHVP+ Q+ +K+ + AP YVLGPLV D+
Sbjct: 252 LAELKVLGELVEKAWKHDVQAMVEGPGHVPLHQVEFNMKIQQEWCHEAPFYVLGPLVLDV 311
Query: 302 FPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAVNLLRF 361
PGYDHI AIGGA+A GA LCY+TP EHLGLPNVE V++GVIA K+AAHA ++ +
Sbjct: 312 APGYDHIGSAIGGALAGWAGAAMLCYITPKEHLGLPNVEDVKQGVIAYKIAAHAADIAKH 371
Query: 362 EDEYRK-DYEMSLARGNLNWARQFEIAFDKDK----FIEIRKERPTKT-EACSMCG-DLC 414
R D MS+AR N +W +QFE+A D + E + KT + CSMCG + C
Sbjct: 372 WPGARDWDLAMSIARYNFDWNKQFELAMDPETARAYHDETLPQEGYKTAKFCSMCGPEFC 431
Query: 415 AIKIIQEMLTK 425
+ KI Q++ K
Sbjct: 432 SYKISQKVQEK 442
>pir||H81389 thiamin biosynthesis protein ThiC Cj0453 [imported] - Campylobacter
jejuni (strain NCTC 11168) >gi|6967924|emb|CAB75091.1|
(AL139075) thiamin biosynthesis protein ThiC
[Campylobacter jejuni]
Length = 430
Score = 374 bits (949), Expect = e-102
Identities = 191/429 (44%), Positives = 269/429 (62%), Gaps = 4/429 (0%)
Query: 2 TQMEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVRV 61
TQM AK+G+ T EM +A +E +S D L + +A G +I N H + P +G G+R
Sbjct: 3 TQMNYAKEGIFTKEMQIVAQKENLSKDFLLENIACGKIIIPANINHKSLDPNGIGFGLRT 62
Query: 62 KVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGTV 121
KVN N+G S D ++ EE++K ++A K+G + IMDLS G R +++ IGTV
Sbjct: 63 KVNVNLGVSNDCVDYSEEMKKVELAHKFGIEAIMDLSNYGKTSRFRDELVNVSKAMIGTV 122
Query: 122 PIYQAAEEMLAKGKAIIEMTEDDMWRAIEKHFKDGVDFATVHVGVTKEVVEKMKRIKRVV 181
P+Y A + K + ++ D + H K GVDF T+H G+ K+ KR+
Sbjct: 123 PVYDAVGFL---EKDLKQINAKDFLDVVYHHAKSGVDFMTIHAGINSRAAHIFKQSKRLT 179
Query: 182 GMVSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDELQ 241
+VSRGG+ L AW++ + ENP ++ YD LL++ +YDV LSLGD LRPG DA D Q
Sbjct: 180 NIVSRGGSVLYAWMMMKDAENPFFEYYDDLLDICLKYDVTLSLGDALRPGSTHDASDGAQ 239
Query: 242 IAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGPLVTDI 301
I+EL L L +RA G+Q M+EGPGH+ I++I A ++L K AP YVLGPLVTDI
Sbjct: 240 ISELIELSLLTQRAWDVGIQVMIEGPGHMAINEIEANMQLEKRLCKGAPFYVLGPLVTDI 299
Query: 302 FPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAVNLLRF 361
GYDHI+GAIGGA+AA +GAD LCYVTPAEHL LPN+E VREG++A K+AAHA ++ +
Sbjct: 300 GAGYDHISGAIGGAVAAASGADMLCYVTPAEHLRLPNLEDVREGIVATKIAAHAGDIAKL 359
Query: 362 EDEYRKDYEMSLARGNLNWARQFEIAFDKDKFIEIRKE-RPTKTEACSMCGDLCAIKIIQ 420
E +D EMS AR ++W + F++A D +K ++ E RP +CSMCG +CA+ +
Sbjct: 360 PKERARDDEMSKARQEIDWEKMFKLAIDGEKAKKMFNERRPDDLNSCSMCGKMCAMNTMN 419
Query: 421 EMLTKKQTS 429
++L + S
Sbjct: 420 QILKGEDVS 428
>gb|AAG19196.1| (AE005016) thiamine biosynthesis protein; ThiC [Halobacterium sp.
NRC-1]
Length = 476
Score = 367 bits (931), Expect = e-100
Identities = 198/427 (46%), Positives = 266/427 (61%), Gaps = 13/427 (3%)
Query: 2 TQMEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVRV 61
TQ++ A+ G +TD M +A+REG P+ +R+ VA G+ VI N HD + P+ +G
Sbjct: 3 TQLQHARDGTVTDAMRRVADREGRDPEVVREAVADGHAVIPANHHHDALDPMIIGRDFAT 62
Query: 62 KVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGTV 121
KVNANIG S ++++E+EK AV YGADT+MDLSTG +LD IR + VP+GTV
Sbjct: 63 KVNANIGNSDTTGDIDDELEKLHTAVHYGADTVMDLSTGENLDGIRTANIDNSPVPVGTV 122
Query: 122 PIYQAAEEMLAKGKAIIEMTEDDMWRAIEKHFKDGVDFATVHVGVTKEVVEKMKRIKRVV 181
PIY+A + + + ++T D + +EK K GVD+ T+H GV E + R
Sbjct: 123 PIYEAVTRV----EDVTDITPDLLIDVVEKQAKQGVDYMTLHAGVLAEHLPLTD--DRTT 176
Query: 182 GMVSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDELQ 241
G+VSRGG+ L+ W+ ++NPLY YD L E+ + +DV +SLGDGLRPG + DA D+ Q
Sbjct: 177 GIVSRGGSILSQWMTEHGEQNPLYTHYDELCEILQAHDVTISLGDGLRPGSVADASDDAQ 236
Query: 242 IAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGPLVTDI 301
AEL TLG L +RA GVQ MVEGPGHVP+DQI A + + D AP YVLGPLVTDI
Sbjct: 237 FAELDTLGELTRRAWDHGVQAMVEGPGHVPMDQIRANVDRQQEVCDGAPFYVLGPLVTDI 296
Query: 302 FPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAVNLLRF 361
PGYDHI AIG AA GA LCYVTP EHLGLP+ E VR+G+ A ++AAHA ++
Sbjct: 297 APGYDHITSAIGATEAARAGAAMLCYVTPKEHLGLPDAEDVRDGMAAYRIAAHAGDVAAG 356
Query: 362 EDEYRK-DYEMSLARGNLNWARQFEIAFDKDKFIEIRK-----ERPTKTEACSMCG-DLC 414
+ R D +S AR N +W RQF++A D ++ + CSMCG D C
Sbjct: 357 KPGARDWDDALSEARYNFDWNRQFDLALDPERAQAFHDQTLPGDNYKDARFCSMCGVDFC 416
Query: 415 AIKIIQE 421
+++I Q+
Sbjct: 417 SMRIDQD 423
>dbj|BAB05652.1| (AP001513) thiamin biosynthesis protein [Bacillus halodurans]
Length = 595
Score = 346 bits (878), Expect = 3e-94
Identities = 192/435 (44%), Positives = 259/435 (59%), Gaps = 20/435 (4%)
Query: 1 MTQMEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVR 60
+TQM AKKG++T EM ++A RE +SP+ +R +A+G ++ N H +P+ +G
Sbjct: 137 VTQMHYAKKGIVTPEMEFVAIRENVSPEFVRDELARGRAILPSNINHPESEPMIIGRNFH 196
Query: 61 VKVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGT 120
VK+NANIG S ++ EE+EK A ++GADTIMDLSTG ++ R I++ VP+GT
Sbjct: 197 VKINANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRNSPVPVGT 256
Query: 121 VPIYQAAEEMLAKGKAIIEMTEDDMWRAIE----KHFKDGVDFATVHVGVTKEVVEKMKR 176
VPIYQA E++ + ED W + + GVD+ T+H GV +
Sbjct: 257 VPIYQALEKVNG-------VAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPLTA- 308
Query: 177 IKRVVGMVSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDA 236
KRV G+VSRGG+ +A W L+ ++EN LY ++ + E+ K YD+ SLGDGLRPG + DA
Sbjct: 309 -KRVTGIVSRGGSIMAQWCLYHHKENFLYTHFEEICEIMKTYDIAFSLGDGLRPGSIADA 367
Query: 237 GDELQIAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGP 296
DE Q AEL TLG L K A + VQ MVEGPGHVP+ QI + AP Y LGP
Sbjct: 368 NDEAQFAELETLGELTKIAWEHDVQVMVEGPGHVPMHQIKENMDKQLDICQEAPFYTLGP 427
Query: 297 LVTDIFPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAV 356
L TDI PGYDHI AIG A+ G LCYVTP EHLGLPN + VREGVI K+AAHA
Sbjct: 428 LTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNKDDVREGVITYKIAAHAA 487
Query: 357 NLLR-FEDEYRKDYEMSLARGNLNWARQFEIAFDKDKFIEIRKE----RPTKT-EACSMC 410
+L + ++D +S AR W QF ++ D ++ +E E KT CSMC
Sbjct: 488 DLAKGHPGAQKRDDALSKARFEFRWRDQFNLSLDPERAMEFHDETLPAEGAKTAHFCSMC 547
Query: 411 G-DLCAIKIIQEMLT 424
G C+++I Q++ T
Sbjct: 548 GPKFCSMRISQDIRT 562
>sp|P45740|THIC_BACSU THIAMINE BIOSYNTHESIS PROTEIN THIC >gi|7448740|pir||D69722 thiamin
biosynthesis protein thiA [accepted] - Bacillus subtilis
>gi|1673401|emb|CAB04805.1| (Z82044) 65.9 kd protein
[Bacillus subtilis] >gi|2633202|emb|CAB12707.1| (Z99108)
thiA [Bacillus subtilis]
Length = 590
Score = 344 bits (873), Expect = 1e-93
Identities = 194/433 (44%), Positives = 257/433 (58%), Gaps = 20/433 (4%)
Query: 1 MTQMEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVR 60
+TQM AKKG+IT EM +IA RE +SP+ +R VA G +I N H +P+ +G
Sbjct: 132 VTQMHYAKKGIITPEMEFIAIREHVSPEFVRDEVASGRAIIPSNINHPESEPMIIGRNFH 191
Query: 61 VKVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGT 120
VK+NANIG S ++EEE+EK A+++GADT+MDLSTG D+ R I++ VP+GT
Sbjct: 192 VKINANIGNSAVTSSIEEEVEKMTWAIRWGADTMMDLSTGKDIHTTREWIIRNCPVPVGT 251
Query: 121 VPIYQAAEEMLAKGKAIIEMTEDDMWR----AIEKHFKDGVDFATVHVGVTKEVVEKMKR 176
VPIYQA E++ + ED W + + + GVD+ T+H GV V
Sbjct: 252 VPIYQALEKVNG-------VAEDLTWEIYRDTLIEQAEQGVDYFTIHAGVLLRYVPLTA- 303
Query: 177 IKRVVGMVSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDA 236
KR G+VSRGG +A W L +QE+ LY ++ + E+ K YD+ SLGDGLRPG + DA
Sbjct: 304 -KRTTGIVSRGGAIMAQWCLAHHQESFLYTHFEEICEIMKMYDIAFSLGDGLRPGSIADA 362
Query: 237 GDELQIAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGP 296
DE Q AEL TLG L + A K VQ M+EGPGHVP+ +I + AP Y LGP
Sbjct: 363 NDEAQFAELETLGELTQIAWKHDVQVMIEGPGHVPMHKIKENVDKQMDICKEAPFYTLGP 422
Query: 297 LVTDIFPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAV 356
L TDI PGYDHI AIG A+ G LCYVTP EHLGLPN + VREGVI K+AAHA
Sbjct: 423 LTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNRDDVREGVITYKIAAHAA 482
Query: 357 NLLRFEDEYR-KDYEMSLARGNLNWARQFEIAFDKDKFIEIRKE----RPTKT-EACSMC 410
+L + + +D +S AR W QF ++ D ++ +E E KT CSMC
Sbjct: 483 DLAKGHPGAQIRDDALSKARFEFRWRDQFNLSLDPERALEYHDETLPAEGAKTAHFCSMC 542
Query: 411 G-DLCAIKIIQEM 422
G C+++I Q++
Sbjct: 543 GPKFCSMRISQDI 555
>sp|Q9X9U0|THIC_STRCO THIAMINE BIOSYNTHESIS PROTEIN THIC >gi|7481451|pir||T37181 thiamin
biosynthesis protein thiC SCQ11.11 [similarity] -
Streptomyces coelicolor >gi|5457278|emb|CAB46966.1|
(AL096823) putative thiamine biosynthesis protein
[Streptomyces coelicolor A3(2)]
Length = 612
Score = 344 bits (872), Expect = 2e-93
Identities = 191/429 (44%), Positives = 262/429 (60%), Gaps = 12/429 (2%)
Query: 1 MTQMEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVR 60
+TQ+ A++G IT EM Y+A RE +SP+ +R+ +A G V+ N H ++P+ +G
Sbjct: 148 VTQLAYARRGEITPEMEYVAVRENVSPEVVREEIAAGRAVLPANINHPEIEPMIIGKRFL 207
Query: 61 VKVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGT 120
VKVNANIG S ++EEE++K A ++GADT+MDLSTG ++ R +++ VPIGT
Sbjct: 208 VKVNANIGNSAVTSSIEEEVDKMTWATRWGADTVMDLSTGRNIHTTREWVLRNSPVPIGT 267
Query: 121 VPIYQAAEEMLAKGKAIIEMTEDDMWRAIEKHFKDGVDFATVHVGVTKEVVEKMKRIKRV 180
VP+YQA E++ + + E+T + + + + GVD+ TVH GV V R
Sbjct: 268 VPLYQALEKVDGRAE---ELTWEIYKDTVIEQAEQGVDYMTVHAGVRLPYVPLTAN--RK 322
Query: 181 VGMVSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDEL 240
G+VSRGG+ +AAW L ++E+ LY++++ L E+ YDV SLGDGLRPG + DA DE
Sbjct: 323 TGIVSRGGSIMAAWCLAHHKESFLYENFEELCEILAAYDVTYSLGDGLRPGSIADANDEA 382
Query: 241 QIAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGPLVTD 300
Q AEL TLG L + A++ VQTM+EGPGHVP+ +I I L + D AP Y LGPL TD
Sbjct: 383 QFAELRTLGELNRIAKRCSVQTMIEGPGHVPMHKIKENIDLQQEICDEAPFYTLGPLTTD 442
Query: 301 IFPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAVNLLR 360
+ P YDHI IG A+ A G LCYVTP EHLGLPN + V+ GVI K+AAHA +L +
Sbjct: 443 VAPAYDHITSGIGAAMIAWWGTAMLCYVTPKEHLGLPNRDDVKTGVITYKIAAHAADLAK 502
Query: 361 FEDEYRK-DYEMSLARGNLNWARQFEIAFDKDKFIEIRKE----RPTKT-EACSMCG-DL 413
++ D +S AR W QF +A D D E E P KT CSMCG
Sbjct: 503 GHPGAQEWDDALSDARFEFRWEDQFNLALDPDTAREFHDETLPAEPAKTAHFCSMCGPKF 562
Query: 414 CAIKIIQEM 422
C++KI Q +
Sbjct: 563 CSMKISQSI 571
>sp|P96269|THIC_MYCTU THIAMINE BIOSYNTHESIS PROTEIN THIC >gi|7448741|pir||E70630 thiamin
biosynthesis protein thiC - Mycobacterium tuberculosis
(strain H37RV) >gi|1817689|emb|CAB06563.1| (Z84724) thiC
[Mycobacterium tuberculosis]
Length = 547
Score = 343 bits (870), Expect = 3e-93
Identities = 194/428 (45%), Positives = 261/428 (60%), Gaps = 12/428 (2%)
Query: 2 TQMEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVRV 61
TQ++ A+ G IT EM +IA RE +S + +R VA+G VI N H +P+ +G V
Sbjct: 82 TQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVIPANHHHPESEPMIIGKAFAV 141
Query: 62 KVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGTV 121
KVNANIG S ++ EE++K A ++GADTIMDLSTG ++ E R I++ VP+GTV
Sbjct: 142 KVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTV 201
Query: 122 PIYQAAEEMLAKGKAIIEMTEDDMWRAIEKHFKDGVDFATVHVGVTKEVVEKMKRIKRVV 181
PIYQA E++ KG E+T + + + + GVD+ TVH GV V KRV
Sbjct: 202 PIYQALEKV--KGDPT-ELTWEIYRDTVIEQCEQGVDYMTVHAGVLLRYVPLTA--KRVT 256
Query: 182 GMVSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDELQ 241
G+VSRGG+ +AAW L ++E+ LY +++ L ++ YDV SLGDGLRPG + DA D Q
Sbjct: 257 GIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDGLRPGSIADANDAAQ 316
Query: 242 IAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGPLVTDI 301
AEL TLG L K A+ G Q M+EGPGH+P+ +I ++L + + AP Y LGPL TDI
Sbjct: 317 FAELRTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCEEAPFYTLGPLATDI 376
Query: 302 FPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAVNLLRF 361
P YDHI AIG AI A G LCYVTP EHLGLP+ + V++GVIA K+AAHA +L +
Sbjct: 377 APAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIAAHAADLAKG 436
Query: 362 EDE-YRKDYEMSLARGNLNWARQFEIAFDKDKFIEIRKE----RPTKT-EACSMCG-DLC 414
+D +S AR W QF ++ D D E E P KT CSMCG C
Sbjct: 437 HPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAEPAKTAHFCSMCGPKFC 496
Query: 415 AIKIIQEM 422
+++I Q++
Sbjct: 497 SMRITQDV 504
>sp|Q9ZBL0|THIC_MYCLE THIAMINE BIOSYNTHESIS PROTEIN THIC >gi|11279601|pir||T44743
probable thiamin biosythesis protein thiC [imported] -
Mycobacterium leprae >gi|4154058|emb|CAA22712.1|
(AL035159) putative thiamine biosythesis protein ThiC
[Mycobacterium leprae]
Length = 547
Score = 336 bits (852), Expect = 3e-91
Identities = 190/428 (44%), Positives = 261/428 (60%), Gaps = 12/428 (2%)
Query: 2 TQMEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVRV 61
TQ++ A+ G IT EM +IA+REG+ + +R VA G VI N H ++P+ +G V
Sbjct: 86 TQLQRARAGEITAEMAFIADREGMPAELVRVEVALGRAVIPANHNHPEIEPMIIGKAFAV 145
Query: 62 KVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGTV 121
KVNANIG S ++ EEI+K A ++GADTIMDLSTG ++ E R I++ VP+GTV
Sbjct: 146 KVNANIGNSAVTSSIAEEIDKMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTV 205
Query: 122 PIYQAAEEMLAKGKAIIEMTEDDMWRAIEKHFKDGVDFATVHVGVTKEVVEKMKRIKRVV 181
PIYQA E++ KG ++T + + + + GVD+ TVH GV V + KRV
Sbjct: 206 PIYQALEKV--KGDPT-KLTWEIYRDTVIEQCEQGVDYMTVHAGVLLRYV--LLTAKRVT 260
Query: 182 GMVSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDELQ 241
G+VSRGG+ +A+W L ++E+ LY ++ L ++ YDV SLGDGLRPG + DA D Q
Sbjct: 261 GIVSRGGSIMASWCLANHRESFLYTNFAELCDIFARYDVTFSLGDGLRPGSIADANDTAQ 320
Query: 242 IAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGPLVTDI 301
AEL TLG L K A+ G Q M+EGPGH+P+ +I ++L + + AP Y LGPL TDI
Sbjct: 321 FAELRTLGELSKIAKVHGAQVMIEGPGHIPMHKIVENVRLEEELCEEAPFYTLGPLATDI 380
Query: 302 FPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAVNLLR- 360
P YDHI AIG A+ A G LCYVTP EHLGLP+ + V++GVIA K+AAHA +L +
Sbjct: 381 APAYDHITSAIGAAVIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIAAHAADLAKG 440
Query: 361 FEDEYRKDYEMSLARGNLNWARQFEIAFDKDKFIEIRKE----RPTKT-EACSMCG-DLC 414
+ +D +S AR W QF ++ D E E P KT CSMCG C
Sbjct: 441 YPRAQERDDALSTARFEFRWNDQFALSLDPPTAREFHDETLPAEPAKTAHFCSMCGPKFC 500
Query: 415 AIKIIQEM 422
+++I ++
Sbjct: 501 SMRITADI 508
>gb|AAA68243.1| (U26178) thiA gene product [Bacillus subtilis]
Length = 590
Score = 335 bits (851), Expect = 4e-91
Identities = 189/421 (44%), Positives = 247/421 (57%), Gaps = 19/421 (4%)
Query: 1 MTQMEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVR 60
+TQM AK+G+IT EM +IA RE +SP+ +R VA G + N H +P+ +G
Sbjct: 132 VTQMHYAKQGIITPEMEFIAIREHVSPEFVRDEVASGRRLFLPNINHPESEPMIIGRNFH 191
Query: 61 VKVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGT 120
VK+NANIG S ++EEE+EK A+++GADT+MDLSTG D+ R I++ VP+GT
Sbjct: 192 VKINANIGNSAVTSSIEEEVEKMTWAIRWGADTMMDLSTGKDIHTTREWIIRNCPVPVGT 251
Query: 121 VPIYQAAEEMLAKGKAIIEMTEDDMWR----AIEKHFKDGVDFATVHVGVTKEVVEKMKR 176
VPIYQA E++ + ED W + + + GVD+ T+H GV V
Sbjct: 252 VPIYQALEKVNG-------VAEDLTWEIYRDTLIEQAEQGVDYFTIHAGVLLRYVPLTA- 303
Query: 177 IKRVVGMVSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDA 236
KR G+VSRGG +A W L +QE+ LY + + E+ K YD+ SLGDGLRPG + DA
Sbjct: 304 -KRTTGIVSRGGAIMAQWCLAHHQESFLYTHLEEICEIMKMYDIAFSLGDGLRPGSIADA 362
Query: 237 GDELQIAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGP 296
DE Q AEL TLG L + A K VQ M+EGPGHVP+ +I + AP Y LGP
Sbjct: 363 NDEAQFAELETLGELTQIAWKHDVQVMIEGPGHVPMHKIKENVDKQMDICKEAPFYTLGP 422
Query: 297 LVTDIFPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAV 356
L TDI PGYDHI AIG A+ G LCYVTP EHLGLPN + VREGVI K+AAHA
Sbjct: 423 LTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNRDDVREGVITYKIAAHAA 482
Query: 357 NLLRFEDEYR-KDYEMSLARGNLNWARQFEIAFDKDKFIEIRKE----RPTKT-EACSMC 410
+L + + +D +S AR W QF ++ D ++ +E E KT CSMC
Sbjct: 483 DLAKGHPGAQIRDDALSKARFEFRWRDQFNLSLDPERALEYHDETLPAEGAKTAHFCSMC 542
Query: 411 G 411
G
Sbjct: 543 G 543
>gb|AAC35232.1| (AC005496) putative thiamin biosynthesis protein [Arabidopsis
thaliana]
Length = 644
Score = 335 bits (851), Expect = 4e-91
Identities = 191/429 (44%), Positives = 258/429 (59%), Gaps = 14/429 (3%)
Query: 2 TQMEDAKKGVITDEMLYIANREGISPDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVRV 61
TQM AK+G+IT+EMLY A RE + P+ +R VA+G +I NK H ++P+ VG V
Sbjct: 164 TQMYYAKQGIITEEMLYCATREKLDPEFVRSEVARGRAIIPSNKKHLELEPMIVGRKFLV 223
Query: 62 KVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGTV 121
KVNANIG S ++EEE+ K + A +GADTIMDLSTG + E R I++ VP+GTV
Sbjct: 224 KVNANIGNSAVASSIEEEVYKVQWATMWGADTIMDLSTGRHIHETREWILRNSAVPVGTV 283
Query: 122 PIYQAAEEMLAKGKAIIEMTEDDMWR-AIEKHFKDGVDFATVHVGVTKEVVEKMKRIKRV 180
PIYQA E++ I E +++R + + + GVD+ T+H GV + KR+
Sbjct: 284 PIYQALEKV----DGIAENLNWEVFRETLIEQAEQGVDYFTIHAGVLLRYIPLTA--KRL 337
Query: 181 VGMVSRGGTFLAAWILHWNQENPLYKDYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDEL 240
G+VSRGG+ A W L +++EN Y+ +D +L++ +YDV LS+GDGLRPG + DA D
Sbjct: 338 TGIVSRGGSIHAKWCLAYHKENFAYEHWDDILDICNQYDVALSIGDGLRPGSIYDANDTA 397
Query: 241 QIAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQIPAQIKLMKVATDNAPVYVLGPLVTD 300
Q AEL T G L +RA + VQ M EGPGHVP+ +IP ++ + AP Y LGPL TD
Sbjct: 398 QFAELLTQGELTRRAWEKDVQVMNEGPGHVPMHKIPENMQKQLEWCNEAPFYTLGPLTTD 457
Query: 301 IFPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLGLPNVEHVREGVIAAKLAAHAVNLLR 360
I PGYDHI AIG A G LCYVTP EHLGLPN + V+ GVIA K+AAHA +L +
Sbjct: 458 IAPGYDHITSAIGAANIGALGTALLCYVTPKEHLGLPNRDDVKAGVIAYKIAAHAADLAK 517
Query: 361 FEDEYRK-DYEMSLARGNLNWARQFEIAFDKDKFIEIRKERPTKTEA-----CSMCG-DL 413
+ D +S AR W QF ++ D + E A CSMCG
Sbjct: 518 QHPHAQAWDDALSKARFEFRWMDQFALSLDPMTAMSFHDETLPADGAKVAHFCSMCGPKF 577
Query: 414 CAIKIIQEM 422
C++KI +++
Sbjct: 578 CSMKITEDI 586
>pir||C83024 thiamin biosynthesis protein ThiC PA4973 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9951256|gb|AAG08358.1|AE004910_5 (AE004910) thiamin
biosynthesis protein ThiC [Pseudomonas aeruginosa]
Length = 627
Score = 326 bits (828), Expect = 2e-88
Identities = 192/457 (42%), Positives = 253/457 (55%), Gaps = 40/457 (8%)
Query: 1 MTQMEDAKKGVITDEMLYIANREG----------------------------ISPDKLRK 32
++QM AKKG+IT EM YIA RE I+P+ +R+
Sbjct: 138 VSQMHYAKKGIITPEMEYIAIRENMKLQEARAAGLLDQQHPGHSFGANIPKEITPEFVRE 197
Query: 33 LVAKGYTVIFRNKVHDWVKPVAVGSGVRVKVNANIGTSRDIINVEEEIEKAKVAVKYGAD 92
VA+G +I N H ++P+ +G VK+N NIG S ++EEE+EK +++GAD
Sbjct: 198 EVARGRAIIPANINHTELEPMIIGRNFLVKINGNIGNSALGSSIEEEVEKLTWGIRWGAD 257
Query: 93 TIMDLSTGGDLDEIRRKIMKAVDVPIGTVPIYQAAEEMLAKGKAIIEMTEDDMWRAIEKH 152
T+MDLSTG + E R I++ VPIGTVPIYQA E++ + ++T + + +
Sbjct: 258 TVMDLSTGKHIHETREWILRNSPVPIGTVPIYQALEKVNGVAE---DLTWEIFRDTLIEQ 314
Query: 153 FKDGVDFATVHVGVTKEVVEKMKRIKRVVGMVSRGGTFLAAWILHWNQENPLYKDYDYLL 212
+ GVD+ T+H GV V KRV G+VSRGG+ +A W L +QEN LY ++ +
Sbjct: 315 AEQGVDYFTIHAGVLLRYVPLTA--KRVTGIVSRGGSIMAKWCLAHHQENFLYTHFEEIC 372
Query: 213 ELAKEYDVVLSLGDGLRPGGLPDAGDELQIAELYTLGRLVKRARKAGVQTMVEGPGHVPI 272
E+ K YDV SLGDGLRPG + DA D Q EL TLG L K A K VQ M+EGPGHVP+
Sbjct: 373 EIMKAYDVSFSLGDGLRPGSVADANDAAQFGELETLGELTKIAWKHDVQVMIEGPGHVPM 432
Query: 273 DQIPAQIKLMKVATDNAPVYVLGPLVTDIFPGYDHIAGAIGGAIAALNGADFLCYVTPAE 332
I + D AP Y LGPL TDI PGYDHI IG A+ G LCYVTP E
Sbjct: 433 QLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKE 492
Query: 333 HLGLPNVEHVREGVIAAKLAAHAVNLLRFEDEYR-KDYEMSLARGNLNWARQFEIAFDKD 391
HLGLPN + V+ G+I K+AAHA +L + + +D +S AR W QF + D D
Sbjct: 493 HLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPD 552
Query: 392 KFIEIRKERPTKTEA-----CSMCG-DLCAIKIIQEM 422
E K A CSMCG C++KI QE+
Sbjct: 553 TARAFHDETLPKDSAKVAHFCSMCGPKFCSMKITQEV 589
>pir||B75614 thiamin biosynthesis protein thiC DRA0175 [similarity] -
Deinococcus radiodurans (strain R1)
>gi|6460490|gb|AAF12196.1|AE001862_22 (AE001862) thiamin
biosynthesis ThiC [Deinococcus radiodurans]
Length = 607
Score = 323 bits (818), Expect = 3e-87
Identities = 192/454 (42%), Positives = 255/454 (55%), Gaps = 37/454 (8%)
Query: 1 MTQMEDAKKGVITDEMLYIANREGI-------------------------SPDKLRKLVA 35
+TQM+ A++G IT EM ++A RE + +P+ +R VA
Sbjct: 129 ITQMQAARRGEITPEMEFVALRENLRQQEQAELAHQHPGESFGASLPRLYTPEFVRDEVA 188
Query: 36 KGYTVIFRNKVHDWVKPVAVGSGVRVKVNANIGTSRDIINVEEEIEKAKVAVKYGADTIM 95
+G VI N H ++P +G RVK+NAN+GTS ++EEE+EK A ++GADT+M
Sbjct: 189 RGRAVIPANVNHPELEPTIIGRNFRVKINANLGTSIVTSSIEEEVEKMVWATRWGADTVM 248
Query: 96 DLSTGGDLDEIRRKIMKAVDVPIGTVPIYQAAEEMLAKGKAIIEMTEDDMWRAIEKHFKD 155
DLSTG + + R I++ VPIGTVPIYQA E++ K + E+T + + + +
Sbjct: 249 DLSTGRHIHQTREWIVRNSPVPIGTVPIYQALEKVDGKAE---ELTWEVYRDTLIEQAEQ 305
Query: 156 GVDFATVHVGVTKEVVEKMKRIKRVVGMVSRGGTFLAAWILHWNQENPLYKDYDYLLELA 215
GVD+ T+H GV V R R G+VSRGG+ LA W L +QEN LY + + E+
Sbjct: 306 GVDYFTIHAGVRLAHVPLTAR--RRTGIVSRGGSILAKWCLAHHQENFLYTRFAEICEIM 363
Query: 216 KEYDVVLSLGDGLRPGGLPDAGDELQIAELYTLGRLVKRARKAGVQTMVEGPGHVPIDQI 275
YDV SLGDGLRPG + DA D Q AEL TLG L + A GVQTM+EGPGHVP+ I
Sbjct: 364 AAYDVTFSLGDGLRPGSIEDANDAAQFAELGTLGELTRVAWDHGVQTMIEGPGHVPMQLI 423
Query: 276 PAQIKLMKVATDNAPVYVLGPLVTDIFPGYDHIAGAIGGAIAALNGADFLCYVTPAEHLG 335
+ AP Y LGPL TDI PGYDHI AIG A A G LCYVTP EHLG
Sbjct: 424 RENMTRQLDVCQEAPFYTLGPLTTDIAPGYDHITSAIGAAQIAWYGTAMLCYVTPKEHLG 483
Query: 336 LPNVEHVREGVIAAKLAAHAVNLLR-FEDEYRKDYEMSLARGNLNWARQFEIAFDKDKFI 394
LP+ + VR+GVI K+AAHA +L + +D +S AR W QF +A D +K
Sbjct: 484 LPDKQDVRDGVITYKIAAHAADLAKGHPGAQARDNAISKARFEFRWQDQFNLALDPEKAR 543
Query: 395 EIRKERPTKTEA-----CSMCGD-LCAIKIIQEM 422
+ E A CSMCG C++K+ ++
Sbjct: 544 ALHDETLPADAAKTAHFCSMCGPAFCSMKLSHDI 577
>pir||E82624 thiamin biosynthesis protein XF1888 [imported] - Xylella fastidiosa
(strain 9a5c) >gi|9106981|gb|AAF84694.1|AE004009_1
(AE004009) thiamine biosynthesis protein [Xylella
fastidiosa]
Length = 629
Score = 321 bits (813), Expect = 1e-86
Identities = 185/456 (40%), Positives = 256/456 (55%), Gaps = 39/456 (8%)
Query: 1 MTQMEDAKKGVITDEMLYIANREG---------------------------ISPDKLRKL 33
+TQ+E A++G++T EM ++A RE I+P+ +R
Sbjct: 160 VTQLEYARRGLVTPEMEFVAIREQQRREQTVENLRGQRHAGDAWGALVGTPITPEFVRDE 219
Query: 34 VAKGYTVIFRNKVHDWVKPVAVGSGVRVKVNANIGTSRDIINVEEEIEKAKVAVKYGADT 93
+A+G ++ N H +P+ +G K+NANIGTS ++ EE+EK A+++GADT
Sbjct: 220 IARGRAILPNNINHPESEPMIIGRNFLTKINANIGTSALSSSIAEEVEKLVWAIRWGADT 279
Query: 94 IMDLSTGGDLDEIRRKIMKAVDVPIGTVPIYQAAEEMLAKGKAIIEMTEDDMWRAIEKHF 153
IMDLSTG D+ R I++ VP+GTVPIYQA E++ +A+ D + +
Sbjct: 280 IMDLSTGRDIHATREWILRNSPVPVGTVPIYQALEKVGGHVEALSWAVFRD---TLIEQA 336
Query: 154 KDGVDFATVHVGVTKEVVEKMKRIKRVVGMVSRGGTFLAAWILHWNQENPLYKDYDYLLE 213
+ GVD+ TVH GV ++ + R+ G+VSRGG+ +A W EN LY ++ L E
Sbjct: 337 EQGVDYVTVHAGVLRDFIPLTA--SRLTGIVSRGGSIMARWCQAHRSENFLYTHFEELCE 394
Query: 214 LAKEYDVVLSLGDGLRPGGLPDAGDELQIAELYTLGRLVKRARKAGVQTMVEGPGHVPID 273
+ + YDV SLGDGLRPG + DA D Q AEL LG L A VQ MVEGPGHVP+
Sbjct: 395 IMRAYDVAFSLGDGLRPGCIADANDAAQFAELEILGELTHIAWNHQVQVMVEGPGHVPMH 454
Query: 274 QIPAQIKLMKVATDNAPVYVLGPLVTDIFPGYDHIAGAIGGAIAALNGADFLCYVTPAEH 333
I A + A AP Y LGPL TDI PGYDHI AIG A+ G LCYVTP EH
Sbjct: 455 LIKANMDKQLAACGEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEH 514
Query: 334 LGLPNVEHVREGVIAAKLAAHAVNLLRFEDEYR-KDYEMSLARGNLNWARQFEIAFDKDK 392
LGLPN++ V +G+IA K+AAHA +L + + +D +S AR W QF ++ D +K
Sbjct: 515 LGLPNLQDVHDGIIAYKIAAHAADLAKGHPAAQARDDALSKARFEFRWQDQFHLSLDPEK 574
Query: 393 FIEIR-----KERPTKTEACSMCG-DLCAIKIIQEM 422
+ + KE + CSMCG C++KI QE+
Sbjct: 575 ALALHDESLPKEAHKRAAFCSMCGPQFCSMKISQEV 610
>pir||H82368 thiamin biosynthesis protein ThiC VC0061 [imported] - Vibrio
cholerae (group O1 strain N16961)
>gi|9654456|gb|AAF93239.1| (AE004097) thiamin
biosynthesis protein ThiC [Vibrio cholerae]
Length = 645
Score = 318 bits (807), Expect = 6e-86
Identities = 190/458 (41%), Positives = 258/458 (55%), Gaps = 43/458 (9%)
Query: 1 MTQMEDAKKGVITDEMLYIANREG---------------------------ISPDKLRKL 33
+TQ+ A++G+IT EM ++A RE I+P+ +R+
Sbjct: 143 VTQLHYARQGIITPEMEFVAIRENSRRLAHQDPSLLQQHAGQNFGAHLPDLITPEFVRRE 202
Query: 34 VAKGYTVIFRNKVHDWVKPVAVGSGVRVKVNANIGTSRDIINVEEEIEKAKVAVKYGADT 93
+A+G +I N H +P+ +G VKVNANIG S ++EEE+EK A ++GADT
Sbjct: 203 IAEGRAIIPCNINHPESEPMIIGRNFLVKVNANIGNSSVSSSIEEEVEKLVWATRWGADT 262
Query: 94 IMDLSTGGDLDEIRRKIMKAVDVPIGTVPIYQAAEEMLAKGKAIIEMTEDDMWRAIEKHF 153
+MDLSTG ++ E R I++ VPIGTVP+YQA E++ + +T + M + +
Sbjct: 263 VMDLSTGRNIHETREWILRNSPVPIGTVPMYQALEKVNGVAE---NLTWEVMRDTLLEQA 319
Query: 154 KDGVDFATVHVGVTKEVVEKMKRIKRVVGMVSRGGTFLAAWILHWNQENPLYKDYDYLLE 213
+ GVD+ T+H G+ V KRV G+VSRGG+ +A W L +QEN LY + + E
Sbjct: 320 EQGVDYFTIHAGLLLRYVPMTA--KRVTGIVSRGGSIIAKWCLSHHQENFLYTHFREICE 377
Query: 214 LAKEYDVVLSLGDGLRPGGLPDAGDELQIAELYTLGRLVKRARKAGVQTMVEGPGHVPID 273
+ +YDV LSLGDGLRPG + DA DE Q AEL TLG L + A + VQ M+EGPGHVP+
Sbjct: 378 ICAQYDVALSLGDGLRPGSIADANDEAQFAELRTLGELTQIAWEYDVQVMIEGPGHVPMH 437
Query: 274 QIPAQIKLMKVATDNAPVYVLGPLVTDIFPGYDHIAGAIGGAIAALNGADFLCYVTPAEH 333
I A + AP Y LGPL TDI PGYDHI IG A+ G LCYVTP EH
Sbjct: 438 LIKANMDEQLKHCHEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEH 497
Query: 334 LGLPNVEHVREGVIAAKLAAHAVNLLRFEDEYR-KDYEMSLARGNLNWARQFEIAFD--- 389
LGLPN E V+ G+I KLAAHA +L + + +D +S AR W QF +A D
Sbjct: 498 LGLPNKEDVKTGLITYKLAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLALDPVT 557
Query: 390 ----KDKFIEIRKERPTKTEACSMCG-DLCAIKIIQEM 422
D+ + +E CSMCG C++KI QE+
Sbjct: 558 ARAFHDE--TLPQESGKVAHFCSMCGPKFCSMKISQEV 593
>pir||C81956 thiamin biosynthesis protein NMA0397 [imported] - Neisseria
meningitidis (group A strain Z2491)
>gi|7379150|emb|CAB83698.1| (AL162753) thiamin
biosynthesis protein [Neisseria meningitidis Z2491]
Length = 633
Score = 317 bits (804), Expect = 1e-85
Identities = 187/463 (40%), Positives = 255/463 (54%), Gaps = 46/463 (9%)
Query: 1 MTQMEDAKKGVITDEMLYIANREG----------------------------------IS 26
+TQ+ A++G+IT EM ++A RE I+
Sbjct: 146 VTQLHYARQGIITPEMEFVAIRERLKLDELSQKPEYAKLLKQHAGQSFGANIPTHPDQIT 205
Query: 27 PDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVRVKVNANIGTSRDIINVEEEIEKAKVA 86
P+ +R+ +A G +I N H ++P+ +G RVK+N N+G S ++ EE+EK +
Sbjct: 206 PEFVRREIAAGRAIIPANINHPELEPMIIGRNFRVKINGNLGNSAVTSSLTEEVEKMVWS 265
Query: 87 VKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGTVPIYQAAEEMLAKGKAIIEMTEDDMW 146
+++GADTIMDLSTG + E R I++ VPIGTVPIYQA E+ G ++T D
Sbjct: 266 LRWGADTIMDLSTGAHIHETREWIIRNAPVPIGTVPIYQALEKT---GGIAEDLTWDLFR 322
Query: 147 RAIEKHFKDGVDFATVHVGVTKEVVEKMKRIKRVVGMVSRGGTFLAAWILHWNQENPLYK 206
+ + + GVD+ T+H GV V R+ G+VSRGG+ +A W L ++EN LY
Sbjct: 323 DTLIEQAEQGVDYFTIHAGVLLRYVPMTAN--RLTGIVSRGGSIMAKWCLAHHRENFLYT 380
Query: 207 DYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDELQIAELYTLGRLVKRARKAGVQTMVEG 266
+D + E+ K YDV SLGDGLRPG + DA DE Q AEL+TLG L +A K VQ M+EG
Sbjct: 381 HFDEICEIMKAYDVSFSLGDGLRPGCIADANDESQFAELHTLGELTDKAWKHDVQVMIEG 440
Query: 267 PGHVPIDQIPAQIKLMKVATDNAPVYVLGPLVTDIFPGYDHIAGAIGGAIAALNGADFLC 326
PGHVP+ ++ + AP Y LGPLVTDI PGYDHI IG A G LC
Sbjct: 441 PGHVPLQRVKENMTEELQHCFEAPFYTLGPLVTDIAPGYDHITSGIGAANIGWYGTAMLC 500
Query: 327 YVTPAEHLGLPNVEHVREGVIAAKLAAHAVNLLR-FEDEYRKDYEMSLARGNLNWARQFE 385
YVTP EHLGLP+ E VR G+I KLAAHA +L + + +D +S AR W QF
Sbjct: 501 YVTPKEHLGLPDKEDVRTGIITYKLAAHAADLAKGWPGAQLRDNALSKARFEFRWRDQFR 560
Query: 386 IAFDKDKFIEIRKERPTKTEA-----CSMCG-DLCAIKIIQEM 422
++ D ++ E A CSMCG C++KI QE+
Sbjct: 561 LSLDPERAESFHDETLPAEGAKIAHFCSMCGPKFCSMKITQEV 603
>pir||E81012 thiamin biosynthesis protein ThiC NMB2040 [imported] - Neisseria
meningitidis (group B strain MD58)
>gi|7227302|gb|AAF42361.1| (AE002554) thiamine
biosynthesis protein ThiC [Neisseria meningitidis MC58]
Length = 633
Score = 317 bits (803), Expect = 2e-85
Identities = 187/463 (40%), Positives = 255/463 (54%), Gaps = 46/463 (9%)
Query: 1 MTQMEDAKKGVITDEMLYIANREG----------------------------------IS 26
+TQ+ A++G+IT EM ++A RE I+
Sbjct: 146 VTQLHYARQGIITPEMEFVAIRERLKLDELSQKPEYAKLLEQHAGQSFGANIPTHPDQIT 205
Query: 27 PDKLRKLVAKGYTVIFRNKVHDWVKPVAVGSGVRVKVNANIGTSRDIINVEEEIEKAKVA 86
P+ +R+ +A G +I N H ++P+ +G RVK+N N+G S ++ EE+EK +
Sbjct: 206 PEFVRQEIAAGRAIIPANINHPELEPMIIGRNFRVKINGNLGNSAVTSSLTEEVEKMVWS 265
Query: 87 VKYGADTIMDLSTGGDLDEIRRKIMKAVDVPIGTVPIYQAAEEMLAKGKAIIEMTEDDMW 146
+++GADTIMDLSTG + E R I++ VPIGTVPIYQA E+ G ++T D
Sbjct: 266 LRWGADTIMDLSTGAHIHETREWIIRNAPVPIGTVPIYQALEKT---GGIAEDLTWDLFR 322
Query: 147 RAIEKHFKDGVDFATVHVGVTKEVVEKMKRIKRVVGMVSRGGTFLAAWILHWNQENPLYK 206
+ + + GVD+ T+H GV V R+ G+VSRGG+ +A W L ++EN LY
Sbjct: 323 DTLIEQAEQGVDYFTIHAGVLLRYVPMTAN--RLTGIVSRGGSIMAKWCLAHHRENFLYT 380
Query: 207 DYDYLLELAKEYDVVLSLGDGLRPGGLPDAGDELQIAELYTLGRLVKRARKAGVQTMVEG 266
+D + E+ K YDV SLGDGLRPG + DA DE Q AEL+TLG L +A K VQ M+EG
Sbjct: 381 HFDEICEIMKAYDVSFSLGDGLRPGCIADANDESQFAELHTLGELTDKAWKHDVQVMIEG 440
Query: 267 PGHVPIDQIPAQIKLMKVATDNAPVYVLGPLVTDIFPGYDHIAGAIGGAIAALNGADFLC 326
PGHVP+ ++ + AP Y LGPLVTDI PGYDHI IG A G LC
Sbjct: 441 PGHVPLQRVKENMTEELQHCFEAPFYTLGPLVTDIAPGYDHITSGIGAANIGWYGTAMLC 500
Query: 327 YVTPAEHLGLPNVEHVREGVIAAKLAAHAVNLLR-FEDEYRKDYEMSLARGNLNWARQFE 385
YVTP EHLGLP+ E VR G+I KLAAHA +L + + +D +S AR W QF
Sbjct: 501 YVTPKEHLGLPDKEDVRTGIITYKLAAHAADLAKGWPGAQLRDNALSKARFEFRWRDQFR 560
Query: 386 IAFDKDKFIEIRKERPTKTEA-----CSMCG-DLCAIKIIQEM 422
++ D ++ E A CSMCG C++KI QE+
Sbjct: 561 LSLDPERAESFHDETLPAEGAKIAHFCSMCGPKFCSMKITQEV 603
>gb|AAF33523.1| (AF170176) 93% identity over 631 amino acids with E. coli thiamine
biosynthesis protein (THIC) (SW:P30136) [Salmonella
typhimurium LT2]
Length = 631
Score = 316 bits (800), Expect = 4e-85
Identities = 190/462 (41%), Positives = 255/462 (55%), Gaps = 51/462 (11%)
Query: 1 MTQMEDAKKGVITDEMLYIANREG---------------------------ISPDKLRKL 33
+TQ+ A+KG++T EM +IA RE I+P+ +R
Sbjct: 147 VTQLHYARKGIVTPEMEFIAIRENMGRERIRSEVLRHQHPGMNFGARLPENITPEFVRDE 206
Query: 34 VAKGYTVIFRNKVHDWVKPVAVGSGVRVKVNANIGTSRDIINVEEEIEKAKVAVKYGADT 93
VA G +I N H +P+ +G VKVNANIG S ++EEE+EK + ++GADT
Sbjct: 207 VAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADT 266
Query: 94 IMDLSTGGDLDEIRRKIMKAVDVPIGTVPIYQAAEEMLAKGKAIIEMTEDDMWRAIE--- 150
+MDLSTG + E R I++ VPIGTVPIYQA E++ + ED W A
Sbjct: 267 VMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNG-------IAEDLTWEAFRDTL 319
Query: 151 -KHFKDGVDFATVHVGVTKEVVEKMKRIKRVVGMVSRGGTFLAAWILHWNQENPLYKDYD 209
+ + GVD+ T+H GV V KR+ G+VSRGG+ +A W L ++EN L++ +
Sbjct: 320 LEQAEQGVDYFTIHAGVLLRYVPMTA--KRLTGIVSRGGSIMAKWCLSHHKENFLFEHFR 377
Query: 210 YLLELAKEYDVVLSLGDGLRPGGLPDAGDELQIAELYTLGRLVKRARKAGVQTMVEGPGH 269
+ E+ YDV LSLGDGLRPG + DA DE Q +EL+TLG L K A + VQ M+EGPGH
Sbjct: 378 EICEICAAYDVSLSLGDGLRPGSIQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGH 437
Query: 270 VPIDQIPAQIKLMKVATDNAPVYVLGPLVTDIFPGYDHIAGAIGGAIAALNGADFLCYVT 329
VP+ I + + AP Y LGPL TDI PGYDH IG A+ G LCYVT
Sbjct: 438 VPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVT 497
Query: 330 PAEHLGLPNVEHVREGVIAAKLAAHAVNLLRFEDEYR-KDYEMSLARGNLNWARQFEIAF 388
P EHLGLPN E V++G+I K+AAHA +L + + +D MS AR W QF +A
Sbjct: 498 PKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLAL 557
Query: 389 D-------KDKFIEIRKERPTKTEACSMCG-DLCAIKIIQEM 422
D D+ + +E CSMCG C++KI QE+
Sbjct: 558 DPFTARAYHDE--TLPQESGKVAHFCSMCGPKFCSMKISQEV 597
>sp|P30136|THIC_ECOLI THIAMINE BIOSYNTHESIS PROTEIN THIC >gi|7430378|pir||E65206 thiamin
biosynthesis protein thiC - Escherichia coli
>gi|396333|gb|AAC43092.1| (U00006) CG Site No. 115
[Escherichia coli] >gi|1790427|gb|AAC76968.1| (AE000473)
thiamin biosynthesis, pyrimidine moiety [Escherichia
coli K12]
Length = 631
Score = 315 bits (799), Expect = 6e-85
Identities = 191/462 (41%), Positives = 253/462 (54%), Gaps = 51/462 (11%)
Query: 1 MTQMEDAKKGVITDEMLYIANREGISPDKLRKLV-------------------------- 34
+TQ+ A++G+IT EM +IA RE + +++R V
Sbjct: 147 VTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGAHLPENITAEFVRDE 206
Query: 35 -AKGYTVIFRNKVHDWVKPVAVGSGVRVKVNANIGTSRDIINVEEEIEKAKVAVKYGADT 93
A G +I N H +P+ +G VKVNANIG S ++EEE+EK + ++GADT
Sbjct: 207 VAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADT 266
Query: 94 IMDLSTGGDLDEIRRKIMKAVDVPIGTVPIYQAAEEMLAKGKAIIEMTEDDMWRAIE--- 150
+MDLSTG + E R I++ VPIGTVPIYQA E++ + ED W A
Sbjct: 267 VMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNG-------IAEDLTWEAFRDTL 319
Query: 151 -KHFKDGVDFATVHVGVTKEVVEKMKRIKRVVGMVSRGGTFLAAWILHWNQENPLYKDYD 209
+ + GVD+ T+H GV V KR+ G+VSRGG+ +A W L +QEN LY+ +
Sbjct: 320 LEQAEQGVDYFTIHAGVLLRYVPMTA--KRLTGIVSRGGSIMAKWCLSHHQENFLYQHFR 377
Query: 210 YLLELAKEYDVVLSLGDGLRPGGLPDAGDELQIAELYTLGRLVKRARKAGVQTMVEGPGH 269
+ E+ YDV LSLGDGLRPG + DA DE Q AEL+TLG L K A + VQ M+EGPGH
Sbjct: 378 EICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGH 437
Query: 270 VPIDQIPAQIKLMKVATDNAPVYVLGPLVTDIFPGYDHIAGAIGGAIAALNGADFLCYVT 329
VP+ I + AP Y LGPL TDI PGYDH IG A+ G LCYVT
Sbjct: 438 VPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVT 497
Query: 330 PAEHLGLPNVEHVREGVIAAKLAAHAVNLLRFEDEYR-KDYEMSLARGNLNWARQFEIAF 388
P EHLGLPN E V++G+I K+AAHA +L + + +D MS AR W QF +A
Sbjct: 498 PKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLAL 557
Query: 389 D-------KDKFIEIRKERPTKTEACSMCG-DLCAIKIIQEM 422
D D+ + +E CSMCG C++KI QE+
Sbjct: 558 DPFTARAYHDE--TLPQESGKVAHFCSMCGPKFCSMKISQEV 597
>pir||S35117 thiC protein - Escherichia coli >gi|414232|gb|AAB95616.1| (M88701)
thiC [Escherichia coli]
Length = 627
Score = 315 bits (799), Expect = 6e-85
Identities = 191/462 (41%), Positives = 253/462 (54%), Gaps = 51/462 (11%)
Query: 1 MTQMEDAKKGVITDEMLYIANREGISPDKLRKLV-------------------------- 34
+TQ+ A++G+IT EM +IA RE + +++R V
Sbjct: 147 VTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGAHLPENITAEFVRDE 206
Query: 35 -AKGYTVIFRNKVHDWVKPVAVGSGVRVKVNANIGTSRDIINVEEEIEKAKVAVKYGADT 93
A G +I N H +P+ +G VKVNANIG S ++EEE+EK + ++GADT
Sbjct: 207 VAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADT 266
Query: 94 IMDLSTGGDLDEIRRKIMKAVDVPIGTVPIYQAAEEMLAKGKAIIEMTEDDMWRAIE--- 150
+MDLSTG + E R I++ VPIGTVPIYQA E++ + ED W A
Sbjct: 267 VMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNG-------IAEDLTWEAFRDTL 319
Query: 151 -KHFKDGVDFATVHVGVTKEVVEKMKRIKRVVGMVSRGGTFLAAWILHWNQENPLYKDYD 209
+ + GVD+ T+H GV V KR+ G+VSRGG+ +A W L +QEN LY+ +
Sbjct: 320 LEQAEQGVDYFTIHAGVLLRYVPMTA--KRLTGIVSRGGSIMAKWCLSHHQENFLYQHFR 377
Query: 210 YLLELAKEYDVVLSLGDGLRPGGLPDAGDELQIAELYTLGRLVKRARKAGVQTMVEGPGH 269
+ E+ YDV LSLGDGLRPG + DA DE Q AEL+TLG L K A + VQ M+EGPGH
Sbjct: 378 EICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGH 437
Query: 270 VPIDQIPAQIKLMKVATDNAPVYVLGPLVTDIFPGYDHIAGAIGGAIAALNGADFLCYVT 329
VP+ I + AP Y LGPL TDI PGYDH IG A+ G LCYVT
Sbjct: 438 VPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVT 497
Query: 330 PAEHLGLPNVEHVREGVIAAKLAAHAVNLLRFEDEYR-KDYEMSLARGNLNWARQFEIAF 388
P EHLGLPN E V++G+I K+AAHA +L + + +D MS AR W QF +A
Sbjct: 498 PKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLAL 557
Query: 389 D-------KDKFIEIRKERPTKTEACSMCG-DLCAIKIIQEM 422
D D+ + +E CSMCG C++KI QE+
Sbjct: 558 DPFTARAYHDE--TLPQESGKVAHFCSMCGPKFCSMKISQEV 597
>sp|O34291|THIC_RHIET THIAMINE BIOSYNTHESIS PROTEIN THIC >gi|11279600|pir||T44254 thiamin
biosynthesis protein thiC [imported] - Rhizobium etli
plasmid b >gi|2627326|gb|AAC45972.1| (AF004408) ThiC
[Rhizobium etli]
Length = 610
Score = 307 bits (778), Expect = 2e-82
Identities = 178/462 (38%), Positives = 251/462 (53%), Gaps = 44/462 (9%)
Query: 1 MTQMEDAKKGVITDEMLYIANREG------------------------ISPDKLRKLVAK 36
+TQ+ A+ G++T EM +IA RE ++P+ +R+ VA+
Sbjct: 127 VTQLAYARAGIVTPEMEFIAIRENLGRQAAKEALARDGESFGAHVPDFVTPEFVRREVAE 186
Query: 37 GYTVIFRNKVHDWVKPVAVGSGVRVKVNANIGTSRDIINVEEEIEKAKVAVKYGADTIMD 96
G +I N H +P+ +G VK+NANIG S ++ EE+EK A+++GADT+MD
Sbjct: 187 GRAIIPANINHPESEPMIIGRNFLVKINANIGNSAVTSSMAEEVEKMVWAIRWGADTVMD 246
Query: 97 LSTGGDLDEIRRKIMKAVDVPIGTVPIYQAAEEMLAKGKAIIEMTEDDMWRAIE----KH 152
LSTG ++ IR I++ VPIGTVP+YQA E++ + ED W +
Sbjct: 247 LSTGRNIHNIREWIIRNSPVPIGTVPLYQALEKVNG-------IAEDLTWEVYRDTLIEQ 299
Query: 153 FKDGVDFATVHVGVTKEVVEKMKRIKRVVGMVSRGGTFLAAWILHWNQENPLYKDYDYLL 212
+ GVD+ T+H GV + + RV G+VSRGG+ + W LH ++E+ LY+ ++ +
Sbjct: 300 AEQGVDYFTIHAGVRLAYIPLT--VNRVTGIVSRGGSIMPTWCLHHHKESFLYEHFEEIC 357
Query: 213 ELAKEYDVVLSLGDGLRPGGLPDAGDELQIAELYTLGRLVKRARKAGVQTMVEGPGHVPI 272
++ + YDV SLGDGLRPG + DA D Q AEL TLG L K A Q M+EGPGHVP+
Sbjct: 358 DICRAYDVSFSLGDGLRPGSIADANDAAQFAELETLGELTKIAWAKDCQVMIEGPGHVPM 417
Query: 273 DQIPAQIKLMKVATDNAPVYVLGPLVTDIFPGYDHIAGAIGGAIAALNGADFLCYVTPAE 332
+I + P Y LGPL TDI PGYDHI IG A+ G LCYVTP E
Sbjct: 418 HKIKENMDKQLEVCGEGPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKE 477
Query: 333 HLGLPNVEHVREGVIAAKLAAHAVNLLRFEDEYR-KDYEMSLARGNLNWARQFEIAFDKD 391
HLGLP+ V+ GVI K+AAHA +L + R +D +S AR W QF ++ D D
Sbjct: 478 HLGLPDRSDVKTGVITYKIAAHAADLAKGHPAARIRDDALSRARFEFRWEDQFNLSLDPD 537
Query: 392 KFIE-----IRKERPTKTEACSMCG-DLCAIKIIQEMLTKKQ 427
+ KE CSMCG C+++I ++ + Q
Sbjct: 538 TARSFHDETLPKEAHKVAHFCSMCGPKFCSMRISHDIRAEAQ 579
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.319 0.138 0.400
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 161417660
Number of Sequences: 2977
Number of extensions: 7018985
Number of successful extensions: 18372
Number of sequences better than 1.0e-10: 29
Number of HSP's better than 0.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 18254
Number of HSP's gapped (non-prelim): 32
length of query: 429
length of database: 189,106,746
effective HSP length: 56
effective length of query: 373
effective length of database: 155,591,474
effective search space: 58035619802
effective search space used: 58035619802
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 166 (69.1 bits)