BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1943 (RTCA) DE:PROBABLE RNA 3'-TERMINAL PHOSPHATE CYCLASE
(EC 6.5.1.4) (RNA-3'- PHOSPHATE CYCLASE) (RNA CYCLASE).
         (342 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

sp|Q9V0Z6|RTCA_PYRAB PROBABLE RNA 3'-TERMINAL PHOSPHATE CYCLASE ...   686  0.0
pir||G71029 probable phosphate cyclase - Pyrococcus horikoshii >...   603  e-171
sp|O59198|RTCA_PYRHO PROBABLE RNA 3'-TERMINAL PHOSPHATE CYCLASE ...   603  e-171
gi|11499030 conserved hypothetical protein [Archaeoglobus fulgid...   310  2e-83
sp|Q60335|RTCA_METJA PROBABLE RNA 3'-TERMINAL PHOSPHATE CYCLASE ...   303  2e-81
gb|AAK42586.1| RNA 3' terminal phosphate cyclase (RNA 3' phospha...   287  9e-77
sp|O27937|RTCA_METTH PROBABLE RNA 3'-TERMINAL PHOSPHATE CYCLASE ...   275  5e-73
sp|O66884|RTCA_AQUAE PROBABLE RNA 3'-TERMINAL PHOSPHATE CYCLASE ...   256  4e-67
sp|Q9YES0|RTCA_AERPE PROBABLE RNA 3'-TERMINAL PHOSPHATE CYCLASE ...   255  6e-67
pir||T13745 hypothetical protein 22E5.3 - fruit fly (Drosophila ...   208  1e-52
gi|4506589 RNA 3'-terminal phosphate cyclase [Homo sapiens] >gi|...   207  1e-52
sp|P46849|RTCA_ECOLI RNA 3'-TERMINAL PHOSPHATE CYCLASE (RNA-3'-P...   201  1e-50
pdb|1QMH|B Chain B, Crystal Structure Of Rna 3'-Terminal Phospha...   201  1e-50
pdb|1QMI|A Chain A, Crystal Structure Of Rna 3'-Terminal Phospha...   197  1e-49
pir||E83072 RNA 3'-terminal phosphate cyclase PA4585 [imported] ...   181  9e-45
sp|O15746|RTC1_DICDI PROBABLE RNA 3'-TERMINAL PHOSPHATE CYCLASE ...   175  7e-43
gb|AAG19210.1| (AE005017) RNA 3'-terminal phosphate cyclase; Tpc...   173  2e-42
pir||G65137 hypothetical 15.4 kD protein in malT-glpR intergenic...   117  2e-25
emb|CAB89811.1| (AJ276894) RNA 3'-terminal phosphate cyclase-lik...    96  6e-19
gi|10946950 RNA cyclase homolog; RNA 3'-terminal phosphate cycla...    96  6e-19
gi|11429125 RNA cyclase homolog [Homo sapiens]                         95  1e-18
dbj|BAB14300.1| (AK022904) unnamed protein product [Homo sapiens]      94  3e-18
sp|Q23400|RTC2_CAEEL PROBABLE RNA 3'-TERMINAL PHOSPHATE CYCLASE ...    89  6e-17
sp|Q09870|RTC1_SCHPO PROBABLE RNA 3'-TERMINAL PHOSPHATE CYCLASE ...    87  3e-16
pir||F65137 hypothetical 21.7 kD protein in malT-glpR intergenic...    81  2e-14
gb|AAA83889.1| (M13585) ORFX; putative [Escherichia coli]              76  6e-13

>sp|Q9V0Z6|RTCA_PYRAB PROBABLE RNA 3'-TERMINAL PHOSPHATE CYCLASE (RNA-3'-PHOSPHATE
           CYCLASE) (RNA CYCLASE) >gi|7450875|pir||D75184 probable
           RNA-3'-phosphate cyclase (EC 6.5.1.4) PAB1943 -
           Pyrococcus abyssi (strain Orsay)
           >gi|5458065|emb|CAB49555.1| (AJ248284) PROBABLE RNA
           3'-TERMINAL PHOSPHATE CYCLASE (EC 6.5.1.4)
           (RNA-3'-PHOSPHATE CYCLASE) (RNA CYCLASE). [Pyrococcus
           abyssi]
           Length = 342
           
 Score =  686 bits (1750), Expect = 0.0
 Identities = 342/342 (100%), Positives = 342/342 (100%)

Query: 1   MITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLAN 60
           MITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLAN
Sbjct: 1   MITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLAN 60

Query: 61  ADVKGAHVGSRELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGG 120
           ADVKGAHVGSRELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGG
Sbjct: 61  ADVKGAHVGSRELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGG 120

Query: 121 TDVPWSPPVDYLANVTLFALEKLGIMAGIKIVRRGHYPKGGGIIEGYVEPWKERRELVAT 180
           TDVPWSPPVDYLANVTLFALEKLGIMAGIKIVRRGHYPKGGGIIEGYVEPWKERRELVAT
Sbjct: 121 TDVPWSPPVDYLANVTLFALEKLGIMAGIKIVRRGHYPKGGGIIEGYVEPWKERRELVAT 180

Query: 181 KYSSIAKVEGISHATNLPAHVAERQAKAAKEELSKLEVPVKIKTEVSKSLGPGSGIVVWA 240
           KYSSIAKVEGISHATNLPAHVAERQAKAAKEELSKLEVPVKIKTEVSKSLGPGSGIVVWA
Sbjct: 181 KYSSIAKVEGISHATNLPAHVAERQAKAAKEELSKLEVPVKIKTEVSKSLGPGSGIVVWA 240

Query: 241 ETDCLRLGGDALGKRGKPAEVVGKEAAQELLEQLKPGYCVDKFLGDQLIPFLAFSGGEIW 300
           ETDCLRLGGDALGKRGKPAEVVGKEAAQELLEQLKPGYCVDKFLGDQLIPFLAFSGGEIW
Sbjct: 241 ETDCLRLGGDALGKRGKPAEVVGKEAAQELLEQLKPGYCVDKFLGDQLIPFLAFSGGEIW 300

Query: 301 VSEVTNHLKTNIWVVENFLGKVFDLDGEVGKPGKVKVVRRVE 342
           VSEVTNHLKTNIWVVENFLGKVFDLDGEVGKPGKVKVVRRVE
Sbjct: 301 VSEVTNHLKTNIWVVENFLGKVFDLDGEVGKPGKVKVVRRVE 342


>pir||G71029 probable phosphate cyclase - Pyrococcus horikoshii
           >gi|3257956|dbj|BAA30639.1| (AP000006) 369aa long
           hypothetical phosphate cyclase [Pyrococcus horikoshii]
           Length = 369
           
 Score =  603 bits (1537), Expect = e-171
 Identities = 280/341 (82%), Positives = 325/341 (95%)

Query: 1   MITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLAN 60
           MITIDGSYGEGGGQILRTS+ALS ITGEPVRI+NIRANRPNPGLRPQHLH ILALKHLAN
Sbjct: 29  MITIDGSYGEGGGQILRTSVALSTITGEPVRIVNIRANRPNPGLRPQHLHAILALKHLAN 88

Query: 61  ADVKGAHVGSRELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGG 120
           A+VKGAHVGSRELVFIPK+LEAK++ ++IGTAGSITLVLQALLPAM FA+ +V+F+ITGG
Sbjct: 89  AEVKGAHVGSRELVFIPKKLEAKEISIDIGTAGSITLVLQALLPAMVFAREKVKFRITGG 148

Query: 121 TDVPWSPPVDYLANVTLFALEKLGIMAGIKIVRRGHYPKGGGIIEGYVEPWKERRELVAT 180
           TDV WSPPVDYL+NVTLFALEK+GI   I+++RRGHYPKGGGI+EGYVEPW E+RELVA 
Sbjct: 149 TDVSWSPPVDYLSNVTLFALEKIGIHGEIRVIRRGHYPKGGGIVEGYVEPWNEKRELVAK 208

Query: 181 KYSSIAKVEGISHATNLPAHVAERQAKAAKEELSKLEVPVKIKTEVSKSLGPGSGIVVWA 240
           +YS I K+EGISHATNLP+HVAERQA+AAK+EL +L+VP++I+TE+S+S+GPGSGIVVWA
Sbjct: 209 EYSRIIKIEGISHATNLPSHVAERQARAAKDELLQLKVPIEIRTEISRSIGPGSGIVVWA 268

Query: 241 ETDCLRLGGDALGKRGKPAEVVGKEAAQELLEQLKPGYCVDKFLGDQLIPFLAFSGGEIW 300
           ETDCLRLGGDALGK+GKPAE+VGKEAAQELL+QLKPG+CVDKFLGDQLIPFLAFSGG IW
Sbjct: 269 ETDCLRLGGDALGKKGKPAEIVGKEAAQELLDQLKPGHCVDKFLGDQLIPFLAFSGGVIW 328

Query: 301 VSEVTNHLKTNIWVVENFLGKVFDLDGEVGKPGKVKVVRRV 341
           VSE+TNHLKTNIWVVE+FLG++FD+DG VG+PGK++V+RRV
Sbjct: 329 VSEITNHLKTNIWVVESFLGRIFDVDGNVGEPGKIRVIRRV 369


>sp|O59198|RTCA_PYRHO PROBABLE RNA 3'-TERMINAL PHOSPHATE CYCLASE (RNA-3'-PHOSPHATE
           CYCLASE) (RNA CYCLASE)
           Length = 341
           
 Score =  603 bits (1537), Expect = e-171
 Identities = 280/341 (82%), Positives = 325/341 (95%)

Query: 1   MITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLAN 60
           MITIDGSYGEGGGQILRTS+ALS ITGEPVRI+NIRANRPNPGLRPQHLH ILALKHLAN
Sbjct: 1   MITIDGSYGEGGGQILRTSVALSTITGEPVRIVNIRANRPNPGLRPQHLHAILALKHLAN 60

Query: 61  ADVKGAHVGSRELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGG 120
           A+VKGAHVGSRELVFIPK+LEAK++ ++IGTAGSITLVLQALLPAM FA+ +V+F+ITGG
Sbjct: 61  AEVKGAHVGSRELVFIPKKLEAKEISIDIGTAGSITLVLQALLPAMVFAREKVKFRITGG 120

Query: 121 TDVPWSPPVDYLANVTLFALEKLGIMAGIKIVRRGHYPKGGGIIEGYVEPWKERRELVAT 180
           TDV WSPPVDYL+NVTLFALEK+GI   I+++RRGHYPKGGGI+EGYVEPW E+RELVA 
Sbjct: 121 TDVSWSPPVDYLSNVTLFALEKIGIHGEIRVIRRGHYPKGGGIVEGYVEPWNEKRELVAK 180

Query: 181 KYSSIAKVEGISHATNLPAHVAERQAKAAKEELSKLEVPVKIKTEVSKSLGPGSGIVVWA 240
           +YS I K+EGISHATNLP+HVAERQA+AAK+EL +L+VP++I+TE+S+S+GPGSGIVVWA
Sbjct: 181 EYSRIIKIEGISHATNLPSHVAERQARAAKDELLQLKVPIEIRTEISRSIGPGSGIVVWA 240

Query: 241 ETDCLRLGGDALGKRGKPAEVVGKEAAQELLEQLKPGYCVDKFLGDQLIPFLAFSGGEIW 300
           ETDCLRLGGDALGK+GKPAE+VGKEAAQELL+QLKPG+CVDKFLGDQLIPFLAFSGG IW
Sbjct: 241 ETDCLRLGGDALGKKGKPAEIVGKEAAQELLDQLKPGHCVDKFLGDQLIPFLAFSGGVIW 300

Query: 301 VSEVTNHLKTNIWVVENFLGKVFDLDGEVGKPGKVKVVRRV 341
           VSE+TNHLKTNIWVVE+FLG++FD+DG VG+PGK++V+RRV
Sbjct: 301 VSEITNHLKTNIWVVESFLGRIFDVDGNVGEPGKIRVIRRV 341


>gi|11499030 conserved hypothetical protein [Archaeoglobus fulgidus]
           >gi|3914932|sp|O28837|RTCA_ARCFU PROBABLE RNA
           3'-TERMINAL PHOSPHATE CYCLASE (RNA-3'-PHOSPHATE CYCLASE)
           (RNA CYCLASE) >gi|7450873|pir||B69429 conserved
           hypothetical protein AF1435 - Archaeoglobus fulgidus
           >gi|2649133|gb|AAB89810.1| (AE001004) conserved
           hypothetical protein [Archaeoglobus fulgidus]
           Length = 328
           
 Score =  310 bits (785), Expect = 2e-83
 Identities = 165/329 (50%), Positives = 217/329 (65%), Gaps = 9/329 (2%)

Query: 1   MITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLAN 60
           MI IDGS+GEGGGQILRT++ALS +TG+ VRI NIRANRP PGL  QHL GI A K ++N
Sbjct: 1   MIEIDGSFGEGGGQILRTAVALSCVTGKAVRIRNIRANRPKPGLAAQHLKGIEAAKIISN 60

Query: 61  ADVKGAHVGSRELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGG 120
           A+V+G  +GS E+VF P  +      V+IGTAGS+TL+ Q +L  + FA       +TGG
Sbjct: 61  AEVEGLRIGSTEIVFNPGSVRGGNFRVDIGTAGSVTLIFQTVLLPLLFADRDSTLTVTGG 120

Query: 121 TDVPWSPPVDYLANVTLFALEKLGIMAGIKIVRRGHYPKGGGIIEGYVEPWKERRELVAT 180
           TDV W+PPVDY  NVTL AL ++G    +++++RG+YPKGGG++   V P  E + +V  
Sbjct: 121 TDVAWAPPVDYFKNVTLRALREMGAECELEVLKRGYYPKGGGMVRLTVRP-AEMKGVVYE 179

Query: 181 KYSSIAKVEGISHATNLPAHVAERQAKAAKEELSKLEVPVKIKTEVSKSLGPGSGIVVWA 240
           +   I  V G+SH  NLP HVAERQA +A+  L +  +  +I+TEV K L  GSGIV+W+
Sbjct: 180 RIDEI--VRGVSHCQNLPGHVAERQASSARNFLEERGIRAEIRTEVLKGLSTGSGIVLWS 237

Query: 241 ETDCLRLGGDALGKRGKPAEVVGKEAAQELLEQLKPGYCVDKFLGDQLIPFLAFSGG--E 298
                  GG ALG+RGK AEVVG+EAA+ L  +L      D  L DQ++PF A + G  E
Sbjct: 238 GYK----GGSALGERGKRAEVVGQEAAESLYRELMSDAAFDAHLADQVMPFAAMARGRTE 293

Query: 299 IWVSEVTNHLKTNIWVVENFLGKVFDLDG 327
              SEVT H K+N +V+  FLGKV   +G
Sbjct: 294 YTTSEVTMHQKSNAYVINTFLGKVVKFEG 322


>sp|Q60335|RTCA_METJA PROBABLE RNA 3'-TERMINAL PHOSPHATE CYCLASE (RNA-3'-PHOSPHATE
           CYCLASE) (RNA CYCLASE) >gi|2128089|pir||A64303 conserved
           hypothetical protein MJ0025 - Methanococcus jannaschii
           >gi|1498784|gb|AAB98006.1| (U67461) hypothetical protein
           [Methanococcus jannaschii]
           Length = 338
           
 Score =  303 bits (768), Expect = 2e-81
 Identities = 157/325 (48%), Positives = 221/325 (67%), Gaps = 7/325 (2%)

Query: 2   ITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLANA 61
           I IDGSY EGGGQI+RT+++LSA+T +PV+IINIR  R N GL PQH+  + A+K L NA
Sbjct: 4   IVIDGSYLEGGGQIIRTAVSLSALTQKPVKIINIRKKRKNKGLAPQHVSAVKAVKKLCNA 63

Query: 62  DVKGAHVGSRELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGGT 121
           +V G +VGS EL FIP +L  K   ++IGTAGSI+LV+Q LLP       +   KI GGT
Sbjct: 64  EVFGLNVGSEELTFIPSKLSPKDFTIDIGTAGSISLVIQTLLPLSLGINKKFTVKIKGGT 123

Query: 122 DVPWSPPVDYLANVTLFALEKLGIMAGIKIVRRGHYPKGGGIIEGYVEPWKERR-ELVAT 180
           DV  +PP+DY+ NVTL  L   G++  +K+++RG YP+GGG +   V+P K ++ +L+  
Sbjct: 124 DVKRAPPIDYVKNVTLKILRNFGVLTELKVLKRGFYPEGGGEVIFEVKPSKIKKFDLIEH 183

Query: 181 KYSSIAKVEGISHATNLPAHVAERQAKAAKEELSKLEVPVKIKTEVSKSLGPGSGIVVWA 240
             S++  VEGIS+  NL   +A R  K A + L+K ++   IK E SK +  G+GIV+W 
Sbjct: 184 SKSNL--VEGISYVQNLDESIARRMRKKAVDLLNKEKLLPNIKIECSKGISTGAGIVLWN 241

Query: 241 ETDCLRLGGDALGKRGKPAEVVGKEAAQELLEQLKPGYCVDKFLGDQLIPFLAFSGGEIW 300
           +T    LGG  LG++G  AE+V + A  ELL++ + G  +DK++GDQ+IPFLAF  G + 
Sbjct: 242 DT----LGGSCLGEKGLRAEIVAERAVNELLKERESGMALDKYMGDQIIPFLAFGKGIVG 297

Query: 301 VSEVTNHLKTNIWVVENFLGKVFDL 325
           VSE+TNH KTN+WVV++FL   F++
Sbjct: 298 VSEITNHTKTNMWVVKHFLDVDFEI 322


>gb|AAK42586.1| RNA 3' terminal phosphate cyclase (RNA 3' phosphate cyclase) (RNA
           cyclase) (rtcA) [Sulfolobus solfataricus]
           Length = 345
           
 Score =  287 bits (728), Expect = 9e-77
 Identities = 152/332 (45%), Positives = 223/332 (66%), Gaps = 9/332 (2%)

Query: 1   MITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLAN 60
           MI IDGS+GEGGGQILRTS+ LS ITG+P RI NIRANRPNPGL+ QHL  + A+K ++N
Sbjct: 9   MIEIDGSFGEGGGQILRTSLTLSVITGKPFRIFNIRANRPNPGLQRQHLWAVRAMKMISN 68

Query: 61  ADVKGAHVGSRELVFIPKRLEAKK-VEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITG 119
           A+ KG  VGS+EL FIP  ++    ++++IGTAGS+TL++Q ++PA+     R+  KI G
Sbjct: 69  AETKGDEVGSKELTFIPHEIKGNSIIDIDIGTAGSVTLIMQTMIPAIINKNMRI--KIKG 126

Query: 120 GTDVPWSPPVDYLANVTLFALEKLGIMAGIKIVRRGHYPKGGG--IIEGYVEPWKERREL 177
           GTDVP SP +DY+  V L  L K+GI + + +++RGHYP+GGG  IIE          + 
Sbjct: 127 GTDVPKSPTIDYIRLVYLEILRKIGIESKVNLIKRGHYPEGGGEVIIENVN---GNPSDF 183

Query: 178 VATKYSSIAKVEGISHATNLPAHVAERQAKAAKEELSKLEVPVKIKTEVSK-SLGPGSGI 236
              +   +  ++GISH ++LP+H+AERQ  +AK  LSKL V ++I+T+V +  +  GSGI
Sbjct: 184 SLLELGKLIMIKGISHVSSLPSHIAERQKDSAKAILSKLGVQIEIETDVRQGEVSKGSGI 243

Query: 237 VVWAETDCLRLGGDALGKRGKPAEVVGKEAAQELLEQLKPGYCVDKFLGDQLIPFLAFSG 296
            + A  +   +G D+LG+RGK AE+VG+EAA++L++ L     VD  + D L+ F +  G
Sbjct: 244 ALAAIGEKSIIGADSLGERGKRAEIVGEEAARKLIDNLNTKAAVDVHMSDMLMIFTSLFG 303

Query: 297 GEIWVSEVTNHLKTNIWVVENFLGKVFDLDGE 328
           GE   +E+T+H  TN+ ++  FL    ++ G+
Sbjct: 304 GEYIGAELTSHAYTNMEIIRKFLDVKIEISGK 335


>sp|O27937|RTCA_METTH PROBABLE RNA 3'-TERMINAL PHOSPHATE CYCLASE (RNA-3'-PHOSPHATE
           CYCLASE) (RNA CYCLASE) >gi|7450872|pir||G69122 conserved
           hypothetical protein MTH1915 - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2623049|gb|AAB86375.1| (AE000942) conserved protein
           [Methanobacterium thermoautotrophicum]
           Length = 337
           
 Score =  275 bits (696), Expect = 5e-73
 Identities = 151/340 (44%), Positives = 216/340 (63%), Gaps = 5/340 (1%)

Query: 1   MITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLAN 60
           MI IDGS GEGGG ++R S AL+A+T   VR+ NIRA R   GL  QHL  + A+  ++N
Sbjct: 1   MIVIDGSEGEGGGAVVRVSTALAAVTSRSVRVYNIRARRSRSGLSHQHLTAVRAVARISN 60

Query: 61  ADVKGAHVGSRELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGG 120
             ++G  +GS EL F P R+       ++ TAGS  LVLQA++ A A ++  ++  ++GG
Sbjct: 61  GTLRGDELGSMELEFSPGRVTGGTFNFDVKTAGSTGLVLQAIMVAAAASEGEIDVTVSGG 120

Query: 121 TDVPWSPPVDYLANVTLFALEKLGIMAGIKIVRRGHYPKGGGIIEGYVEPWKERRELVAT 180
           TDV W+P  DYL  VT+  LE +G  A I+I+RRG+YP+GGG +   +EP + R   +  
Sbjct: 121 TDVLWAPTCDYLREVTIPVLEMMGYSARIEIIRRGYYPEGGGRVHAIIEPSELRP--ITL 178

Query: 181 KYSSIAKVEGISHATNLPAHVAERQAKAAKEELSKLEVPVKIKTE-VSKSLGPGSGIVVW 239
           + S I  V GISH+ NLP HVAERQA++A + L    + V I  E  S  +G GSGI +W
Sbjct: 179 EESEIHAVRGISHSRNLPVHVAERQAESAMKILRGAGLDVDIMVEDASGPVGRGSGITLW 238

Query: 240 AETDCLRLGGDALGKRGKPAEVVGKEAAQELLEQLKPGYCVDKFLGDQLIPFLAFSG-GE 298
           AE +  RLG  +LGK GK AE VG EAA+ELL  ++ G  +D+++GDQ+IP++A +G   
Sbjct: 239 AEGN-TRLGAVSLGKPGKRAEKVGSEAARELLGFIESGSPLDRYMGDQIIPYMALTGDSR 297

Query: 299 IWVSEVTNHLKTNIWVVENFLGKVFDLDGEVGKPGKVKVV 338
           +   E+T H +TNI + E   G+ F ++GE G P  ++V+
Sbjct: 298 VRTCELTLHAETNIILSEKITGRRFRVEGERGGPATIEVL 337


>sp|O66884|RTCA_AQUAE PROBABLE RNA 3'-TERMINAL PHOSPHATE CYCLASE (RNA-3'-PHOSPHATE
           CYCLASE) (RNA CYCLASE) >gi|7450877|pir||H70356 conserved
           hypothetical protein aq_642 - Aquifex aeolicus
           >gi|2983257|gb|AAC06852.1| (AE000700) hypothetical
           protein [Aquifex aeolicus]
           Length = 360
           
 Score =  256 bits (646), Expect = 4e-67
 Identities = 154/357 (43%), Positives = 205/357 (57%), Gaps = 25/357 (7%)

Query: 2   ITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLANA 61
           + +DGSYGEGGGQI+RT++ LS +   PVRI NIRA R  PGL+ QHL+ +  LK  A A
Sbjct: 5   LELDGSYGEGGGQIVRTALFLSTLLQVPVRIYNIRAKREKPGLKRQHLNIVKLLKRFAKA 64

Query: 62  DVKGAHVGSRELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGGT 121
            VKG  +GS EL + P++L+    EVN  TAGSI L LQ +LP   F    V  K+ GGT
Sbjct: 65  KVKGDELGSIELEYKPQKLKPGYYEVNFDTAGSIPLFLQTILPLSLFVPGEVVIKVIGGT 124

Query: 122 DVPWSPPVDYLANVTLFALEKLGIMAGIKIVRRGHYPKGGGIIEGYV------------- 168
           DVP SP +D++  V L  + K+     +++++RG YP GGGI++  V             
Sbjct: 125 DVPKSPTIDWVRFVFLHYIYKVPEFIRLEVLKRGFYPAGGGIVQLSVRNKLEKQPENLQE 184

Query: 169 --EPWKERRELVATKYSSIAKVE--GISHATNLPAHVAERQAKAAKEELSKLEVP-VKIK 223
             E  K++  L  T+   I K+    ++H       VAERQAK A E L  L  P  ++ 
Sbjct: 185 VKEYLKDKVNLYRTERGEIRKIHVFSVAHEELRERKVAERQAKGAIEALKNLGYPEPEVY 244

Query: 224 TEVSKSLGPGSGIVVWAE-TDCLRLGGDALGKRGKPAEVVGKEAAQELLEQLKPGYCVDK 282
            + + +   G+ I +W E T    LG D LGK+GK AEVVG EA ++L E    G  VD+
Sbjct: 245 RQYANANSIGTSITIWLEDTKGNVLGADNLGKKGKLAEVVGAEAVKKLHEDWSSGATVDR 304

Query: 283 FLGDQLIPFLAFSGGEIWVSEVTNHLKTNIWVVENFLGKVFDLDGEVGKPGKVKVVR 339
            L D LIP +A  GGEI V + T HL TNIWV E FLGK+F++D       K K+VR
Sbjct: 305 HLADHLIPLMALVGGEIRVPQFTGHLLTNIWVCEQFLGKIFEVD------EKEKIVR 355


>sp|Q9YES0|RTCA_AERPE PROBABLE RNA 3'-TERMINAL PHOSPHATE CYCLASE (RNA-3'-PHOSPHATE
           CYCLASE) (RNA CYCLASE) >gi|7450874|pir||H72747 probable
           RNA 3'-terminal phosphate cyclase APE0511 - Aeropyrum
           pernix (strain K1) >gi|5104160|dbj|BAA79476.1|
           (AP000059) 353aa long hypothetical RNA 3'-terminal
           phosphate cyclase [Aeropyrum pernix]
           Length = 353
           
 Score =  255 bits (644), Expect = 6e-67
 Identities = 141/347 (40%), Positives = 215/347 (61%), Gaps = 15/347 (4%)

Query: 4   IDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLANADV 63
           +DGS GEGGGQILRT++AL+A+ G P+RI+NIRA R  PGLRPQHL  + A+  ++   +
Sbjct: 1   MDGSMGEGGGQILRTAVALAAVLGRPLRIVNIRAKRRPPGLRPQHLTAVRAVAAISGGRL 60

Query: 64  KGAHVGSRELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGGTDV 123
           +GA VGS  L F P R+   +   ++GTAGS+ L++QAL P +A++ + VE ++TGGTDV
Sbjct: 61  RGAEVGSTSLEFTPGRVRGGRYRFDVGTAGSVALIIQALAPLLAYSDSPVEVELTGGTDV 120

Query: 124 PWSPPVDYLANVTLFALEKLGIMAGIKIVRRGHYPKGGG-IIEGYVEPWKERRELVATKY 182
           P +P +DY+  V    L  LG    I+++RRGHYP+GGG ++    +P    R     + 
Sbjct: 121 PMAPTIDYMREVFASILAMLGYEIEIRVLRRGHYPRGGGRVVVRVPDPPGGFRARSFVER 180

Query: 183 SSIAKVEGISHATNLPAHVAERQAKAAKEEL-SKLEVPVKIKTEVSK-----SLGPGSGI 236
             +  V   SHA  LP  +AERQA++A   +  +L V   ++ E  K      LGPG+G+
Sbjct: 181 GPLKGVYVRSHAVKLPGSIAERQARSAASLVRERLGVDPIVEIEAYKPHRDPHLGPGTGV 240

Query: 237 VVWAETDCLRLGGDALGKRGKPAEVVGKEAAQELLEQLKPGYCVDKFLGDQLIPFLAFSG 296
           +VWA      +GGD++GK+GKPAEVVG+EAA+ LLE +  G  +D+ + D    +LA +G
Sbjct: 241 LVWAVFGETVMGGDSIGKKGKPAEVVGREAAESLLEDMATGAALDRHMSDMAPVYLALAG 300

Query: 297 G--EIWVSEVTNHLKTNI----WVVENFLGKVFDLDGEVGKPGKVKV 337
           G   ++ + +T H  T +     +V+ F  ++  L+G + +P K ++
Sbjct: 301 GVSTVFGARLTGHASTILELLRIMVDGFEYRI--LEGGLERPFKAEL 345


>pir||T13745 hypothetical protein 22E5.3 - fruit fly (Drosophila melanogaster)
           >gi|3676131|emb|CAA21129.1| (AL031765)
           /prediction=(method:""genefinder"", version:""084"",
           score:""51.07"")~/prediction=(method:""genscan"",
           version:""1.0"", score:""133.97"")~/match=(desc:""RNA
           3'-TERMINAL PHOSPHATE CYCLASE 1 (EC 6.5.1.4)
           (RNA-3'-PHOSPHATE CYCLASE 1) (RNA CYCLA>
           >gi|7290258|gb|AAF45719.1| (AE003423) EG:22E5.3 gene
           product [Drosophila melanogaster]
           Length = 361
           
 Score =  208 bits (523), Expect = 1e-52
 Identities = 124/339 (36%), Positives = 191/339 (55%), Gaps = 9/339 (2%)

Query: 1   MITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLAN 60
           M+ IDGSY EGGGQ LR +++LS I G+PVR++ IRA+RP+PGL  QHLHG+  L+ + N
Sbjct: 6   MLEIDGSYLEGGGQALRNALSLSCILGKPVRVVKIRASRPSPGLSHQHLHGLNLLRDITN 65

Query: 61  ADVKGAHVGSRELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGG 120
           ADV G ++ S  + F P+ +      V   TA SITL+ Q  LP + FA       ++GG
Sbjct: 66  ADVVGNYLLSSTVEFTPRTILDNTYRVETHTAASITLIYQMALPVLLFAGRPSRLIVSGG 125

Query: 121 TDVPWSPPVDYLANVTLFALEKLGIMAGIKIVRRGHYPKGGGIIEGYVEPWKERRELVAT 180
           T+V ++PPV+Y+  V L  L+  G+   +K+ R G YP+G G  +  V+P  +       
Sbjct: 126 TNVDFAPPVEYMQEVLLPNLKHFGVSFDLKVQRYGFYPRGQGRCQLDVQPVTKLNSGKLV 185

Query: 181 KYSSIAKVEGISH-ATNLPAHVAERQAKAAKEELSKLEVPVK-----IKTEVSKSLGPGS 234
            +  I  V G+++ A  LP ++A    + A+ E+ +L    +     IK    K+   G+
Sbjct: 186 AFGRIKSVSGVAYCAGRLPVNIAIDMQQTAQREIHRLWPSQQCSIEPIKHSRQKAFHNGA 245

Query: 235 GIVVWAETDC-LRLGGDALGKRGKPAEVVGKEAAQELLEQLKPGYCVDKFLGDQLIPFLA 293
           GI++   T   + LG  ALGK+     V+G EA+ +L + ++   CVD ++ DQLI ++A
Sbjct: 246 GILMTVNTTSDVVLGASALGKKRIDGHVLGSEASCQLGDYMRKQVCVDDYMQDQLIIYMA 305

Query: 294 FSGGE--IWVSEVTNHLKTNIWVVENFLGKVFDLDGEVG 330
            + G   +   ++TNH +T I V E   G  FD+  E G
Sbjct: 306 LAVGRSTMRTGKLTNHTRTAINVAEQMTGVKFDVAMEPG 344


>gi|4506589 RNA 3'-terminal phosphate cyclase [Homo sapiens]
           >gi|2500648|sp|O00442|RTC1_HUMAN RNA 3'-TERMINAL
           PHOSPHATE CYCLASE 1 (RNA-3'-PHOSPHATE CYCLASE 1) (RNA
           CYCLASE 1) >gi|11280306|pir||T48844 RNA-3'-phosphate
           cyclase (EC 6.5.1.4) 1 [validated] - human
           >gi|2125812|emb|CAA72364.1| (Y11651) phosphate cyclase
           [Homo sapiens]
           Length = 366
           
 Score =  207 bits (522), Expect = 1e-52
 Identities = 125/325 (38%), Positives = 186/325 (56%), Gaps = 11/325 (3%)

Query: 2   ITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLANA 61
           + +DGS  EGGGQILR S ALS + G P+R+  IRA R  PGLRPQHL G+  ++ L + 
Sbjct: 6   VEVDGSIMEGGGQILRVSTALSCLLGLPLRVQKIRAGRSTPGLRPQHLSGLEMIRDLCDG 65

Query: 62  DVKGAHVGSRELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGGT 121
            ++GA +GS E+ F P++++      +  TAGS+ L++Q  +P + FA +  E  + GGT
Sbjct: 66  QLEGAEIGSTEITFTPEKIKGGIHTADTKTAGSVCLLMQVSMPCVLFAASPSELHLKGGT 125

Query: 122 DVPWSPPVDYLANVTLFALEKLGIMAGIKIVRRGHYPKGGGIIEGYVEPWKERRELVATK 181
           +   +P +DY   V    +EK G +    I  RG+YPKGGG +   + P K+   +  T+
Sbjct: 126 NAEMAPQIDYTVMVFKPIVEKFGFIFNCDIKTRGYYPKGGGEVIVRMSPVKQLNPINLTE 185

Query: 182 YSSIAKVEGISHATN-LPAHVAERQAKAA----KEELSKLEVPVK-IKTEVSKSLGPGSG 235
              + K+ G +     LP  VA+  A AA    ++E+  L V ++ ++    ++ G G+G
Sbjct: 186 RGCVTKIYGRAFVAGVLPFKVAKDMAAAAVRCIRKEIRDLYVNIQPVQEPKDQAFGNGNG 245

Query: 236 IVVWAETD--CLRLGGDALGKRGKPAEVVGKEAAQELLEQLKPGYCVDKFLGDQLIPFLA 293
           I++ AET   CL   G +LGKRG  A+ VG EAA+ LL  L+ G  VD++L DQLI F+A
Sbjct: 246 IIIIAETSTGCL-FAGSSLGKRGVNADKVGIEAAEMLLANLRHGGTVDEYLQDQLIVFMA 304

Query: 294 FSGG--EIWVSEVTNHLKTNIWVVE 316
            + G   I    VT H +T I   E
Sbjct: 305 LANGVSRIKTGPVTLHTQTAIHFAE 329


>sp|P46849|RTCA_ECOLI RNA 3'-TERMINAL PHOSPHATE CYCLASE (RNA-3'-PHOSPHATE CYCLASE) (RNA
           CYCLASE)
           Length = 339
           
 Score =  201 bits (505), Expect = 1e-50
 Identities = 121/326 (37%), Positives = 178/326 (54%), Gaps = 4/326 (1%)

Query: 1   MITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLAN 60
           MI +DG+ GEGGGQILR++++LS ITG+P  I +IRA R  PGL  QHL  + A   +  
Sbjct: 5   MIALDGAQGEGGGQILRSALSLSMITGQPFTITSIRAGRAKPGLLRQHLTAVKAATEICG 64

Query: 61  ADVKGAHVGSRELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGG 120
           A V+GA +GS+ L+F P  +        IG+AGS TLVLQ +LPA+ FA      +++GG
Sbjct: 65  ATVEGAELGSQRLLFRPGTVRGGDYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSGG 124

Query: 121 TDVPWSPPVDYLANVTLFALEKLGIMAGIKIVRRGHYPKGGGIIEGYVEPWKERRELVAT 180
           TD P +PP D++  V    L K+GI     ++R G YP GGG++   V P      L   
Sbjct: 125 TDNPSAPPADFIRRVLEPLLAKIGIHQQTTLLRHGFYPAGGGVVATEVSPVASFNTLQLG 184

Query: 181 KYSSIAKVEGISHATNLPAHVAERQAKAAKEELSKLEVPVKIKTEVSKSLGPGSGIVVWA 240
           +  +I ++ G      +P HVAER+        S  E  +     + +  GPG+ + +  
Sbjct: 185 ERGNIVQMRGEVLLAGVPRHVAEREIATLAGSFSLHEQNIH---NLPRDQGPGNTVSLEV 241

Query: 241 ETDCLRLGGDALGKRGKPAEVVGKEAAQELLEQLKPGYCVDKFLGDQLIPFLAFSG-GEI 299
           E++ +      +G++   AEVV  +  +E+   L     V ++L DQL+  +A +G GE 
Sbjct: 242 ESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLASTAAVGEYLADQLVLPMALAGAGEF 301

Query: 300 WVSEVTNHLKTNIWVVENFLGKVFDL 325
            V+  + HL TNI VVE FL   F L
Sbjct: 302 TVAHPSCHLLTNIAVVERFLPVRFSL 327


>pdb|1QMH|B Chain B, Crystal Structure Of Rna 3'-Terminal Phosphate Cyclase, An
           Ubiquitous Enzyme With Unusual Topology
           >gi|6980697|pdb|1QMH|A Chain A, Crystal Structure Of Rna
           3'-Terminal Phosphate Cyclase, An Ubiquitous Enzyme With
           Unusual Topology
           Length = 347
           
 Score =  201 bits (505), Expect = 1e-50
 Identities = 121/326 (37%), Positives = 178/326 (54%), Gaps = 4/326 (1%)

Query: 1   MITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLAN 60
           MI +DG+ GEGGGQILR++++LS ITG+P  I +IRA R  PGL  QHL  + A   +  
Sbjct: 5   MIALDGAQGEGGGQILRSALSLSMITGQPFTITSIRAGRAKPGLLRQHLTAVKAATEICG 64

Query: 61  ADVKGAHVGSRELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGG 120
           A V+GA +GS+ L+F P  +        IG+AGS TLVLQ +LPA+ FA      +++GG
Sbjct: 65  ATVEGAELGSQRLLFRPGTVRGGDYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSGG 124

Query: 121 TDVPWSPPVDYLANVTLFALEKLGIMAGIKIVRRGHYPKGGGIIEGYVEPWKERRELVAT 180
           TD P +PP D++  V    L K+GI     ++R G YP GGG++   V P      L   
Sbjct: 125 TDNPSAPPADFIRRVLEPLLAKIGIHQQTTLLRHGFYPAGGGVVATEVSPVASFNTLQLG 184

Query: 181 KYSSIAKVEGISHATNLPAHVAERQAKAAKEELSKLEVPVKIKTEVSKSLGPGSGIVVWA 240
           +  +I ++ G      +P HVAER+        S  E  +     + +  GPG+ + +  
Sbjct: 185 ERGNIVQMRGEVLLAGVPRHVAEREIATLAGSFSLHEQNIH---NLPRDQGPGNTVSLEV 241

Query: 241 ETDCLRLGGDALGKRGKPAEVVGKEAAQELLEQLKPGYCVDKFLGDQLIPFLAFSG-GEI 299
           E++ +      +G++   AEVV  +  +E+   L     V ++L DQL+  +A +G GE 
Sbjct: 242 ESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLASTAAVGEYLADQLVLPMALAGAGEF 301

Query: 300 WVSEVTNHLKTNIWVVENFLGKVFDL 325
            V+  + HL TNI VVE FL   F L
Sbjct: 302 TVAHPSCHLLTNIAVVERFLPVRFSL 327


>pdb|1QMI|A Chain A, Crystal Structure Of Rna 3'-Terminal Phosphate Cyclase, An
           Ubiquitous Enzyme With Unusual Topology
           >gi|6980700|pdb|1QMI|B Chain B, Crystal Structure Of Rna
           3'-Terminal Phosphate Cyclase, An Ubiquitous Enzyme With
           Unusual Topology >gi|6980701|pdb|1QMI|C Chain C, Crystal
           Structure Of Rna 3'-Terminal Phosphate Cyclase, An
           Ubiquitous Enzyme With Unusual Topology
           >gi|6980702|pdb|1QMI|D Chain D, Crystal Structure Of Rna
           3'-Terminal Phosphate Cyclase, An Ubiquitous Enzyme With
           Unusual Topology
           Length = 347
           
 Score =  197 bits (496), Expect = 1e-49
 Identities = 120/325 (36%), Positives = 175/325 (52%), Gaps = 4/325 (1%)

Query: 2   ITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLANA 61
           I +DG+ GEGGGQILR++++LS ITG+P  I +IRA R  PGL  QHL  + A   +  A
Sbjct: 6   IALDGAQGEGGGQILRSALSLSXITGQPFTITSIRAGRAKPGLLRQHLTAVKAATEICGA 65

Query: 62  DVKGAHVGSRELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGGT 121
            V+GA +GS+ L+F P  +        IG+AGS TLVLQ +LPA+ FA      +++GGT
Sbjct: 66  TVEGAELGSQRLLFRPGTVRGGDYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSGGT 125

Query: 122 DVPWSPPVDYLANVTLFALEKLGIMAGIKIVRRGHYPKGGGIIEGYVEPWKERRELVATK 181
           D P +PP D++  V    L K+GI     ++R G YP GGG++   V P      L   +
Sbjct: 126 DNPSAPPADFIRRVLEPLLAKIGIHQQTTLLRHGFYPAGGGVVATEVSPVASFNTLQLGE 185

Query: 182 YSSIAKVEGISHATNLPAHVAERQAKAAKEELSKLEVPVKIKTEVSKSLGPGSGIVVWAE 241
             +I +  G      +P HVAER+        S  E  +     + +  GPG+ + +  E
Sbjct: 186 RGNIVQXRGEVLLAGVPRHVAEREIATLAGSFSLHEQNIH---NLPRDQGPGNTVSLEVE 242

Query: 242 TDCLRLGGDALGKRGKPAEVVGKEAAQELLEQLKPGYCVDKFLGDQLIPFLAFSG-GEIW 300
           ++ +      +G++   AEVV  +  +E+   L     V ++L DQL+   A +G GE  
Sbjct: 243 SENITERFFVVGEKRVSAEVVAAQLVKEVKRYLASTAAVGEYLADQLVLPXALAGAGEFT 302

Query: 301 VSEVTNHLKTNIWVVENFLGKVFDL 325
           V+  + HL TNI VVE FL   F L
Sbjct: 303 VAHPSCHLLTNIAVVERFLPVRFSL 327


>pir||E83072 RNA 3'-terminal phosphate cyclase PA4585 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9950833|gb|AAG07973.1|AE004872_4 (AE004872) RNA
           3'-terminal phosphate cyclase [Pseudomonas aeruginosa]
           Length = 341
           
 Score =  181 bits (455), Expect = 9e-45
 Identities = 109/320 (34%), Positives = 179/320 (55%), Gaps = 5/320 (1%)

Query: 1   MITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLAN 60
           +I +DGS  EGGGQILR++++LS  +G+P+RI NIR  R  PGL  QHL  + A   +  
Sbjct: 5   LIELDGS--EGGGQILRSALSLSMTSGQPLRIRNIRGRRSRPGLLRQHLTAVRAAAEICA 62

Query: 61  ADVKGAHVGSRELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGG 120
           A+V+GA +GSREL F P  + A      IG+AGS +LVLQ LLPA+  A      +I+GG
Sbjct: 63  AEVEGAELGSRELAFRPGAIRAGDYAFAIGSAGSCSLVLQTLLPALLAANGESRVRISGG 122

Query: 121 TDVPWSPPVDYLANVTLFALEKLGIMAGIKIVRRGHYPKGGGIIEGYVEPWKERRELVAT 180
           T  P +PP D+L +  L  L+++G    ++++R G  P GGG +   V P    R L   
Sbjct: 123 THNPLAPPADFLRDSWLPLLQRMGAEVDLELLRHGFVPAGGGELLARVRP-ARWRPLQLE 181

Query: 181 KYSSIAKVEGISHATNLPAHVAERQAKAAKEELSKLEVPVKIKTEVSKSLGPGSGIVVWA 240
              +  + +  +    +P HV ER+ +  ++ L   +   +++  +++  GPG+ +++  
Sbjct: 182 HPGAALRRQARALLAGIPGHVGERELERVRQRLGWSDEERQLEF-LAEDQGPGNALLLRI 240

Query: 241 ETDCLRLGGDALGKRGKPAEVVGKEAAQELLEQLKPGYCVDKFLGDQLIPFLAFSG-GEI 299
           + + +     A G+ G  AE V ++ A + +  ++ G   D+ L DQL+  +A +G G  
Sbjct: 241 DCEHICATFCAFGQAGVSAERVAEQVATQAIGWMESGCAADEHLADQLLLPMALAGAGSF 300

Query: 300 WVSEVTNHLKTNIWVVENFL 319
               ++ HL++N  V+E FL
Sbjct: 301 TTPRLSAHLQSNRRVIERFL 320


>sp|O15746|RTC1_DICDI PROBABLE RNA 3'-TERMINAL PHOSPHATE CYCLASE 1 (RNA-3'-PHOSPHATE
           CYCLASE 1) (RNA CYCLASE 1) >gi|2425127|gb|AAB70847.1|
           (AF020279) similar to H. sapiens phosphate cyclase
           encoded by GenBank Accession Number Y11651
           [Dictyostelium discoideum]
           Length = 433
           
 Score =  175 bits (439), Expect = 7e-43
 Identities = 119/336 (35%), Positives = 181/336 (53%), Gaps = 15/336 (4%)

Query: 4   IDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLANADV 63
           IDGS  EGGGQILR S+AL+++  + + I  IR NR  PGL+ QH  GI  +  L  A +
Sbjct: 38  IDGSILEGGGQILRNSVALASLFNKAISIEKIRYNRDQPGLKNQHKAGIDLMSRLFKAHL 97

Query: 64  KGAHVGSRELVFIPKRLEAKK---VEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGG 120
            G  VGS +L + P +   +    +E +  TAGSI L++Q  LP + FA +  +  + GG
Sbjct: 98  TGCSVGSCKLYYQPTQKTIQDDGVIEADTKTAGSICLMIQVSLPCLIFAPHSTKMVLGGG 157

Query: 121 TDVPWSPPVDYLANVTLFALEKLGIMAGIKIVRRGHYPKGGGIIEGYVEPWKE-RRELVA 179
           T+  ++P  DY+ NV L     +G    + I +RG YPKGGG +    +P  +    +  
Sbjct: 158 TNCDFAPAADYIQNVFLPIATTMGFKCEMSIDKRGFYPKGGGAVTLTTQPLTQPLSPITI 217

Query: 180 TKYSSIAKVEGISHATN--LPAHVAERQAKAAKEELSKLEVPVKIKTE---VSK-SLGPG 233
                + ++   S+ T+  +   VAER    AK+ + K    V ++TE   VSK S G G
Sbjct: 218 VNKGEVNRIVIKSYFTSPRISPLVAERMNNTAKKLIKKDFKKVDVETELIDVSKFSFGDG 277

Query: 234 SGIVVWAETD--CLRLGGDALGKRGKPAEVVGKEAAQELLEQLKPGYCVDKFLGDQLIPF 291
           + I + A TD  C+  G    G  G PAE V ++AA  LL+ L+ G C+D++L DQLI F
Sbjct: 278 TFIEIRAYTDQGCI-FGATGNGAIGVPAEKVAEDAANSLLKDLQDGGCMDEYLQDQLIIF 336

Query: 292 LAFSGG--EIWVSEVTNHLKTNIWVVENFLGKVFDL 325
           +A + G  +I    ++ H +T+I +     G +F +
Sbjct: 337 MALAKGKSQIKTGPISLHTQTSIHITSLMTGAIFTI 372


>gb|AAG19210.1| (AE005017) RNA 3'-terminal phosphate cyclase; Tpc [Halobacterium
           sp. NRC-1]
           Length = 378
           
 Score =  173 bits (435), Expect = 2e-42
 Identities = 123/355 (34%), Positives = 182/355 (50%), Gaps = 40/355 (11%)

Query: 1   MITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLAN 60
           M  +DGS   GGGQ++RT++  +A++GE  R+  +R  R NPGL+ QH   + A+  + +
Sbjct: 40  MHVLDGS--SGGGQLVRTALTCAAVSGESFRMRYVRRARSNPGLQAQHCAAVNAVADICD 97

Query: 61  ADVKGAHVGSRELVFIPKRLEAKKVE------------VNIGTAGSITLVLQALLPAMAF 108
           A   G  VGS    F P+ + A++ +            V +GTAGSI LV  +LLP    
Sbjct: 98  AATDGVEVGSEAFSFEPE-VAAEEADDDEEPTLGGTTSVEVGTAGSIPLVFDSLLPLAGA 156

Query: 109 AKNRVEFKITGGTDVPWSPPVDYLANVTLFALEKLGIMAGIKIVRRGHYPKGGGIIEGYV 168
               +   +TGGTD  W+PP+DY  +V L  L + GI A + + RRG YP+GGG     V
Sbjct: 157 LDEPITATLTGGTDAKWAPPMDYFQHVKLPLLREHGIDATVSVDRRGFYPRGGGEATLTV 216

Query: 169 EP-------WKERRELVA-TKYSSIAKVEGISHATNLPAHVAERQAKAAKEELSKLEVPV 220
           EP         ER +  A T YS       ++ ++     VAE+QA AA  + +      
Sbjct: 217 EPSTPTPITLTERGDREALTAYS-------VAESSLADDEVAEQQATAAAPDAAH----- 264

Query: 221 KIKTEVSKSLGPGSGIVVWAETDCLRLGGDALGKRGKPAEVVGKEAAQELLEQLKPGYCV 280
             +   + +   GS +V+ AE +  R G  ALG+RG  A+ VG+ AA  L         V
Sbjct: 265 --EIAYTDADSAGSAVVLAAEYEHSRAGFAALGERGVSADAVGENAADALAAFESGPGAV 322

Query: 281 DKFLGDQLIPFLAFSGGEIWVSEVTNHLKTNIWVVENFLGKVFDLDGEVGKPGKV 335
           D  L DQL+P +A +GGE+   EVT H++T + ++  F    +D+D E    G V
Sbjct: 323 DSHLADQLVPVVAVAGGEVRAPEVTTHIETCVDLLAEF---DYDIDIEHTDDGAV 374


>pir||G65137 hypothetical 15.4 kD protein in malT-glpR intergenic region -
           Escherichia coli (strain K-12) >gi|606355|gb|AAA58218.1|
           (U18997) ORF_f146 [Escherichia coli]
           >gi|1789826|gb|AAC76445.1| (AE000418) RNA 3'-terminal
           phosphate cyclase [Escherichia coli K12]
           Length = 146
           
 Score =  117 bits (291), Expect = 2e-25
 Identities = 60/128 (46%), Positives = 82/128 (63%)

Query: 1   MITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLAN 60
           MI +DG+ GEGGGQILR++++LS ITG+P  I +IRA R  PGL  QHL  + A   +  
Sbjct: 5   MIALDGAQGEGGGQILRSALSLSMITGQPFTITSIRAGRAKPGLLRQHLTAVKAATEICG 64

Query: 61  ADVKGAHVGSRELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGG 120
           A V+GA +GS+ L+F P  +        IG+AGS TLVLQ +LPA+ FA      +++  
Sbjct: 65  ATVEGAELGSQRLLFRPGTVRGGDYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSAA 124

Query: 121 TDVPWSPP 128
           TD P +PP
Sbjct: 125 TDNPSAPP 132


>emb|CAB89811.1| (AJ276894) RNA 3'-terminal phosphate cyclase-like protein [Homo
           sapiens]
           Length = 373
           
 Score = 96.0 bits (235), Expect = 6e-19
 Identities = 92/317 (29%), Positives = 142/317 (44%), Gaps = 15/317 (4%)

Query: 1   MITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLAN 60
           M T   S    G   LR  + LS ++G PV+I  IRA   NPGLR      I  L  + N
Sbjct: 1   MATQAHSLSYAGCNFLRQRLVLSTLSGRPVKIRKIRARDDNPGLRDFEASFIRLLDKITN 60

Query: 61  ADVKGAHVGSRELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGG 120
                 +     L + P  L    VE +      I   L++LL    F K+ ++  + G 
Sbjct: 61  GSRIEINQTGTTLYYQPGLLYGGSVEHDCSVLRGIGYYLESLLCLAPFMKHPLKIVLRGV 120

Query: 121 TDVPWSPPVDYLANVTLFALEKLGI---MAGIKIVRRGHYPKGGGIIEGYVEPWKERREL 177
           T+    P VD L    L  L++ GI      +KIVRRG  P GGG +       K  + +
Sbjct: 121 TNDQVDPSVDVLKATALPLLKQFGIDGESFELKIVRRGMPPGGGGEVVFSCPVRKVLKPI 180

Query: 178 VATKYSSIAKVEGISHATNLPAHVAERQAKAAKEELSKLEVPVKIKTE----VSKSLGPG 233
             T    I ++ G++++  +   +A R   +A+  L+K    + I T+    V+    PG
Sbjct: 181 QLTDPGKIKRIRGMAYSVRVSPQMANRIVDSARSILNKFIPDIYIYTDHMKGVNSGKSPG 240

Query: 234 SGIVVWAETDC-LRLGGD-ALGKRGKPAEV----VGKEAAQELLEQLKPGYCVDKFLGDQ 287
            G+ + AET     L  + A   +G+ A V    +G+  A+ LLE++  G CVD    +Q
Sbjct: 241 FGLSLVAETTSGTFLSAELASNPQGQGAAVLPEDLGRNCARLLLEEIYRGGCVDS--TNQ 298

Query: 288 LIPFLAFSGGEIWVSEV 304
            +  L  + G+  VS+V
Sbjct: 299 SLALLLMTLGQRDVSKV 315


>gi|10946950 RNA cyclase homolog; RNA 3'-terminal phosphate cyclase-like protein
           [Mus musculus] >gi|7688275|emb|CAB89817.1| (AJ276895)
           RNA 3'-terminal phosphate cyclase-like protein [Mus
           musculus]
           Length = 373
           
 Score = 96.0 bits (235), Expect = 6e-19
 Identities = 93/317 (29%), Positives = 143/317 (44%), Gaps = 15/317 (4%)

Query: 1   MITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLAN 60
           M T   S    G   LR  + LS ++G PV+I  IRA   NPGLR      I  L  + N
Sbjct: 1   MATQAHSLSYAGCNFLRQRLVLSTLSGRPVKIRRIRARDDNPGLRDFEASFIRLLDKITN 60

Query: 61  ADVKGAHVGSRELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGG 120
                 +     L + P  L    VE +      I   L+ALL    F K+ ++  + G 
Sbjct: 61  GSRIEINQTGTTLYYQPGLLYGGSVEHDCSVLRGIGYYLEALLCLAPFMKHPLKIVLRGV 120

Query: 121 TDVPWSPPVDYLANVTLFALEKLGI---MAGIKIVRRGHYPKGGGIIEGYVEPWKERREL 177
           T+    P VD L    L  L++ GI      +KI+RRG  P GGG +       K  + +
Sbjct: 121 TNDQVDPSVDVLKATALPLLKQFGIDGESFELKILRRGMPPGGGGEVLFSCPVRKVLKPV 180

Query: 178 VATKYSSIAKVEGISHATNLPAHVAERQAKAAKEELSKLEVPVKIKTE----VSKSLGPG 233
             T    I ++ G++++  +   +A R   +A+  L+K    + I T+    VS    PG
Sbjct: 181 QLTDPGKIKRIRGMAYSVRVSPQMANRIVDSARSILNKFIPDIYIYTDHMKGVSSGKSPG 240

Query: 234 SGIVVWAE-TDCLRLGGD-ALGKRGKPAEV----VGKEAAQELLEQLKPGYCVDKFLGDQ 287
            G+ + AE T+   L  + A   +G+ A V    +G+  A+ LLE++  G CVD    +Q
Sbjct: 241 FGLSLVAETTNGTFLSAELASNPQGQGAAVLPEDLGRNCAKLLLEEIYRGGCVDS--TNQ 298

Query: 288 LIPFLAFSGGEIWVSEV 304
            +  L  + G+  VS+V
Sbjct: 299 SLVLLLMTLGQQDVSKV 315


>gi|11429125 RNA cyclase homolog [Homo sapiens]
           Length = 366
           
 Score = 94.8 bits (232), Expect = 1e-18
 Identities = 89/306 (29%), Positives = 139/306 (45%), Gaps = 15/306 (4%)

Query: 12  GGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLANADVKGAHVGSR 71
           G   LR  + LS ++G PV+I  IRA   NPGLR      I  L  + N      +    
Sbjct: 5   GCNFLRQRLVLSTLSGRPVKIRKIRARDDNPGLRDFEASFIRLLDKITNGSRIEINQTGT 64

Query: 72  ELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGGTDVPWSPPVDY 131
            L + P  L    VE +      I   L++LL    F K+ ++  + G T+    P VD 
Sbjct: 65  TLYYQPGLLYGGSVEHDCSVLRGIGYYLESLLCLAPFMKHPLKIVLRGVTNDQVDPSVDV 124

Query: 132 LANVTLFALEKLGI---MAGIKIVRRGHYPKGGGIIEGYVEPWKERRELVATKYSSIAKV 188
           L    L  L++ GI      +KIVRRG  P GGG +       K  + +  T    I ++
Sbjct: 125 LKATALPLLKQFGIDGESFELKIVRRGMPPGGGGEVVFSCPVRKVLKPIQLTDPGKIKRI 184

Query: 189 EGISHATNLPAHVAERQAKAAKEELSKLEVPVKIKTE----VSKSLGPGSGIVVWAETDC 244
            G++++  +   +A R   +A+  L+K    + I T+    V+    PG G+ + AET  
Sbjct: 185 RGMAYSVRVSPQMANRIVDSARSILNKFIPDIYIYTDHMKGVNSGKSPGFGLSLVAETTS 244

Query: 245 -LRLGGD-ALGKRGKPAEV----VGKEAAQELLEQLKPGYCVDKFLGDQLIPFLAFSGGE 298
              L  + A   +G+ A V    +G+  A+ LLE++  G CVD    +Q +  L  + G+
Sbjct: 245 GTFLSAELASNPQGQGAAVLPEDLGRNCARLLLEEIYRGGCVDS--TNQSLALLLMTLGQ 302

Query: 299 IWVSEV 304
             VS+V
Sbjct: 303 QDVSKV 308


>dbj|BAB14300.1| (AK022904) unnamed protein product [Homo sapiens]
           Length = 373
           
 Score = 93.6 bits (229), Expect = 3e-18
 Identities = 91/317 (28%), Positives = 141/317 (43%), Gaps = 15/317 (4%)

Query: 1   MITIDGSYGEGGGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLAN 60
           M T   S    G   LR  + LS ++G PV+I  IRA   NPGLR      I  L  + N
Sbjct: 1   MATQAYSLSYAGCNFLRQRLVLSTLSGRPVKIRKIRARDDNPGLRDFEASFIRLLDKITN 60

Query: 61  ADVKGAHVGSRELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGG 120
                 +     L + P  L    VE +      I   L++LL    F K+ ++  + G 
Sbjct: 61  GSRIEINQTGTTLYYQPGLLYGGSVEHDCSVLRGIGYYLESLLCLAPFMKHPLKIVLRGV 120

Query: 121 TDVPWSPPVDYLANVTLFALEKLGI---MAGIKIVRRGHYPKGGGIIEGYVEPWKERREL 177
           T+    P VD L    L  L++ GI      + IVRRG  P GGG +       K  + +
Sbjct: 121 TNDQVDPSVDVLKATALPLLKQFGIDGESFELNIVRRGMPPGGGGEVVFSCPVRKVLKPI 180

Query: 178 VATKYSSIAKVEGISHATNLPAHVAERQAKAAKEELSKLEVPVKIKTE----VSKSLGPG 233
             T    I ++ G++++  +   +A R   +A+  L+K    + I T+    V+    PG
Sbjct: 181 QLTDPGKIKRIRGMAYSVRVSPQMANRIVDSARSILNKFIPDIYIYTDHMKGVNSGKSPG 240

Query: 234 SGIVVWAETDC-LRLGGD-ALGKRGKPAEV----VGKEAAQELLEQLKPGYCVDKFLGDQ 287
            G+ + AET     L  + A   +G+ A V    +G+  A+ LLE++  G CVD    +Q
Sbjct: 241 FGLSLVAETTSGTFLSAELASNPQGQGAAVLPEDLGRNCARLLLEEIYRGGCVDS--TNQ 298

Query: 288 LIPFLAFSGGEIWVSEV 304
            +  L  + G+  VS+V
Sbjct: 299 SLALLLMTLGQQDVSKV 315


>sp|Q23400|RTC2_CAEEL PROBABLE RNA 3'-TERMINAL PHOSPHATE CYCLASE (RNA-3'-PHOSPHATE
           CYCLASE) (RNA CYCLASE)
           Length = 379
           
 Score = 89.3 bits (218), Expect = 6e-17
 Identities = 78/284 (27%), Positives = 126/284 (43%), Gaps = 14/284 (4%)

Query: 12  GGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLANADVKGAHVGSR 71
           G    R  +A S ++G P+RIINIR N   PG+R      I  L+ + N           
Sbjct: 10  GCNFFRIRLAYSILSGRPIRIINIRKNDDRPGIRDFESKLIGLLEKVTNGTKVEISRTGT 69

Query: 72  ELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGGTDVPWSPPVDY 131
           +++F P  +    V ++ GT   I+  L+ LL    F K  +  K+ G T+ P    VD 
Sbjct: 70  QVIFRPGMITGGVVNLDCGTERCISYFLEPLLLLSPFCKVPMVIKLKGVTNAPGEISVDG 129

Query: 132 LANVTLFALEKLGI---MAGIKIVRRGHYPKGGGIIEGYVEPWKERRELVATKYSSIAKV 188
           +    L    K  +      IKI  RG  P+GGG++       K  R +   +   + K+
Sbjct: 130 MKASWLKVYNKFVLNDEKLDIKIQARGLKPEGGGVVVFTAPIVKTLRPVKRQQVGKVCKI 189

Query: 189 EGISHATNLPAHVAERQAKAAKEE----LSKLEVPVKIKTEVSKSLGPGSGIVVWAE-TD 243
            G ++ T +   +A R   AAK+     +S + + V  +   +    PG G+ + AE T+
Sbjct: 190 RGQAYVTKVTPSLAYRMIDAAKKAMHGYISDVYITVDQRKGDAGGASPGYGLFLTAETTE 249

Query: 244 CLRLGGDAL----GKRGKP--AEVVGKEAAQELLEQLKPGYCVD 281
            +    +A+    G+ G P   E +G EA   LL+Q+  G  +D
Sbjct: 250 GVIYQAEAISRPKGESGVPILPEDIGIEAGHALLQQIYMGGALD 293


>sp|Q09870|RTC1_SCHPO PROBABLE RNA 3'-TERMINAL PHOSPHATE CYCLASE (RNA-3'-PHOSPHATE
           CYCLASE) (RNA CYCLASE) >gi|2130253|pir||S62537 probable
           RNA 3'-terminal phosphate cyclase - fission yeast
           (Schizosaccharomyces pombe) >gi|1052524|emb|CAA91501.1|
           (Z66568) probable RNA 3'-terminal phosphate cyclase
           [Schizosaccharomyces pombe]
           Length = 363
           
 Score = 87.0 bits (212), Expect = 3e-16
 Identities = 72/297 (24%), Positives = 132/297 (44%), Gaps = 9/297 (3%)

Query: 12  GGQILRTSIALSAITGEPVRIINIRANRPNPGLRPQHLHGILALKHLANADVKGAHVGSR 71
           G + L   + L+ ++G P+R+  I  +  +PG++   +  +  L+ L N  V        
Sbjct: 11  GCEYLTHRLVLATLSGTPIRVEGIYPDEADPGVKDYQVSFLRLLEKLTNGSVIEISYTGT 70

Query: 72  ELVFIPKRLEAKKVEVNIGTAGSITLVLQALLPAMAFAKNRVEFKITGGTDVPWSPPVDY 131
             ++ P  +   +V  +  T   I   L+ +L    FAK      +TG T       VD 
Sbjct: 71  SFIYRPGNIIGGRVVHDCPTTKGIGYFLEPILILCLFAKTPTSLTLTGVTSSNEDIGVDV 130

Query: 132 LANVTLFALEK---LGIMAGIKIVRRGHYPKGGGIIEGYVEPWKERRELV-ATKYSSIAK 187
           L    L +L+K   +G    ++I++RG  P GGG +       KE    +  +++  + +
Sbjct: 131 LRTSVLPSLQKRFQVGDELELRILKRGSAPGGGGEVNFLCPVIKESLPPIRLSEFGRVFR 190

Query: 188 VEGISHATNLPAHVAERQAKAAKEELSKLEVPVKIKTEVSK----SLGPGSGIVVWAETD 243
           + GI+ +T +    A R  ++A+  L+     V I T+V +       PG  I + AET+
Sbjct: 191 IRGIASSTRVSPAFANRLVESARGVLNPFIPDVFIYTDVRRGDECGNSPGYSITLVAETN 250

Query: 244 -CLRLGGDALGKRGKPAEVVGKEAAQELLEQLKPGYCVDKFLGDQLIPFLAFSGGEI 299
                  +  G+ G+  E VG   A++LLE ++ G CVD +     +  +  S  ++
Sbjct: 251 KGCSYAAEHCGEAGETPEDVGSFCAKKLLEVIESGGCVDPYTQPSTLTGMLLSSEDV 307


>pir||F65137 hypothetical 21.7 kD protein in malT-glpR intergenic region -
           Escherichia coli (strain K-12) >gi|606354|gb|AAA58217.1|
           (U18997) ORF_f201 [Escherichia coli]
           >gi|1789825|gb|AAC76444.1| (AE000418) orf, hypothetical
           protein [Escherichia coli K12]
           Length = 201
           
 Score = 81.1 bits (197), Expect = 2e-14
 Identities = 57/187 (30%), Positives = 90/187 (47%), Gaps = 4/187 (2%)

Query: 140 LEKLGIMAGIKIVRRGHYPKGGGIIEGYVEPWKERRELVATKYSSIAKVEGISHATNLPA 199
           L K+GI     ++R G YP GGG++   V P      L   +  +I ++ G      +P 
Sbjct: 6   LAKIGIHQQTTLLRHGFYPAGGGVVATEVSPVASFNTLQLGERGNIVQMRGEVLLAGVPR 65

Query: 200 HVAERQAKAAKEELSKLEVPVKIKTEVSKSLGPGSGIVVWAETDCLRLGGDALGKRGKPA 259
           HVAER+        S  E  +     + +  GPG+ + +  E++ +      +G++   A
Sbjct: 66  HVAEREIATLAGSFSLHEQNIH---NLPRDQGPGNTVSLEVESENITERFFVVGEKRVSA 122

Query: 260 EVVGKEAAQELLEQLKPGYCVDKFLGDQLIPFLAFSG-GEIWVSEVTNHLKTNIWVVENF 318
           EVV  +  +E+   L     V ++L DQL+  +A +G GE  V+  + HL TNI VVE F
Sbjct: 123 EVVAAQLVKEVKRYLASTAAVGEYLADQLVLPMALAGAGEFTVAHPSCHLLTNIAVVERF 182

Query: 319 LGKVFDL 325
           L   F L
Sbjct: 183 LPVRFSL 189


>gb|AAA83889.1| (M13585) ORFX; putative [Escherichia coli]
           Length = 191
           
 Score = 76.1 bits (184), Expect = 6e-13
 Identities = 53/176 (30%), Positives = 85/176 (48%), Gaps = 4/176 (2%)

Query: 151 IVRRGHYPKGGGIIEGYVEPWKERRELVATKYSSIAKVEGISHATNLPAHVAERQAKAAK 210
           ++R G YP GGG++   V P      L   +  +I ++ G      +P HVAER+     
Sbjct: 7   LLRHGFYPAGGGVVATEVSPVASFNTLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLA 66

Query: 211 EELSKLEVPVKIKTEVSKSLGPGSGIVVWAETDCLRLGGDALGKRGKPAEVVGKEAAQEL 270
              S  E  +     + +  GPG+ + +  E++ +      +G++   AEVV  +  +E+
Sbjct: 67  GSFSLHEQNIH---NLPRDQGPGNTVSLEVESENITERFFVVGEKRVSAEVVAAQLVKEV 123

Query: 271 LEQLKPGYCVDKFLGDQLIPFLAFSG-GEIWVSEVTNHLKTNIWVVENFLGKVFDL 325
              L     V ++L DQL+  +A +G GE  V+  + HL TNI VVE FL   F L
Sbjct: 124 KRYLASTAAVGEYLADQLVLPMALAGAGEFTVAHPSCHLLTNIAVVERFLPVRFSL 179


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.317    0.138    0.403 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 130736172
Number of Sequences: 2977
Number of extensions: 5475968
Number of successful extensions: 12191
Number of sequences better than 1.0e-10: 26
Number of HSP's better than  0.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 12127
Number of HSP's gapped (non-prelim): 26
length of query: 342
length of database: 189,106,746
effective HSP length: 55
effective length of query: 287
effective length of database: 156,189,961
effective search space: 44826518807
effective search space used: 44826518807
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 165 (68.7 bits)