BLASTP 2.0.10 [Aug-26-1999] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= PAB1955 (tldD-like) DE:TLDD RELATED PROTEIN (458 letters) Database: ./suso.pep; /banques/blast2/nr.pep 598,487 sequences; 189,106,746 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value pir||C75180 tldd related protein PAB1955 - Pyrococcus abyssi (st... 923 0.0 pir||E71033 tldD-related protein PH1557 - Pyrococcus horikoshii ... 862 0.0 pir||G71248 tldD homolog PH0246 - Pyrococcus horikoshii >gi|3256... 307 2e-82 sp|Q58403|Y996_METJA HYPOTHETICAL PROTEIN MJ0996 >gi|2826357|gb|... 290 2e-77 pir||A75213 tldd protein PAB0154 - Pyrococcus abyssi (strain Ors... 290 2e-77 pir||D64424 tldD homolog MJ0996 - Methanococcus jannaschii 288 7e-77 emb|CAB57642.1| (Y18930) hypothetical protein [Sulfolobus solfat... 249 4e-65 gb|AAK40965.1| Zn-dependent protease, tldD protein homolog, puta... 249 4e-65 sp|O26944|Y856_METTH HYPOTHETICAL PROTEIN MTH856 >gi|7429832|pir... 239 6e-62 pir||G75033 hypothetical protein PAB1547 - Pyrococcus abyssi (st... 232 6e-60 pir||D71135 tldD-related protein PH0848 - Pyrococcus horikoshii ... 228 8e-59 pir||D72762 hypothetical protein APE0089 - Aeropyrum pernix (str... 194 2e-48 sp|P73754|Y863_SYNY3 HYPOTHETICAL 50.4 KD PROTEIN SLR0863 >gi|74... 192 9e-48 gi|11498263 conserved hypothetical protein [Archaeoglobus fulgid... 180 4e-44 sp|P46473|TLDD_ECOLI TLDD PROTEIN >gi|7429829|pir||F65116 tldD p... 159 5e-38 gb|AAK41402.1| Conserved hypothetical protein [Sulfolobus solfat... 158 1e-37 sp|P57478|TLDD_BUCAI TLDD PROTEIN HOMOLOG >gi|10039067|dbj|BAB13... 153 3e-36 pir||D72342 tldD protein - Thermotoga maritima (strain MSB8) >gi... 153 5e-36 pir||G82325 tldD protein VC0422 [imported] - Vibrio cholerae (gr... 151 2e-35 sp|P74002|YD22_SYNY3 HYPOTHETICAL 53.1 KD PROTEIN SLR1322 >gi|74... 148 9e-35 emb|CAC11942.1| (AL445065) conserved hypothetical protein [Therm... 145 8e-34 pir||F82718 TldD protein XF1127 [imported] - Xylella fastidiosa ... 143 4e-33 sp|P45297|TLDD_HAEIN TLDD PROTEIN HOMOLOG 141 1e-32 pir||D83086 conserved hypothetical protein PA4474 [imported] - P... 139 8e-32 gb|AAC43985.2| (U33883) TldD [Bradyrhizobium japonicum] 133 4e-30 pir||G70473 tldD homolog - Aquifex aeolicus >gi|2984257|gb|AAC07... 127 2e-28 pir||A82033 TLDD protein homolog NMA0367 [imported] - Neisseria ... 125 1e-27 pir||F81010 tldD protein NMB2066 [imported] - Neisseria meningit... 124 2e-27 pir||E72342 pmbA-related protein - Thermotoga maritima (strain M... 117 2e-25 dbj|BAB05755.1| (AP001514) suppressor of the inhibitory activity... 112 7e-24 pir||S70839 tldD homolog - Bradyrhizobium japonicum (fragment) 107 2e-22 pir||D70703 tldD homolog Rv2315c - Mycobacterium tuberculosis (s... 99 1e-19 gb|AAD53904.1|AF176314_14 (AF176314) PmbA [Zymomonas mobilis] 91 2e-17 pir||F71033 hypothetical protein PH1558 - Pyrococcus horikoshii ... 91 3e-17 pir||D82066 pmbA protein VC2535 [imported] - Vibrio cholerae (gr... 89 1e-16 pir||B75213 pmba protein (tlde protein) PAB0155 - Pyrococcus aby... 87 5e-16 pir||B75180 antibiotic/peptide maturation related protein PAB195... 84 3e-15 pir||B83330 hypothetical protein PA2529 [imported] - Pseudomonas... 83 6e-15 pir||T36780 hypothetical protein SCI28.10 - Streptomyces coelico... 83 8e-15 pir||E71135 hypothetical protein PH0849 - Pyrococcus horikoshii ... 80 4e-14 pir||F75033 hypothetical protein PAB1548 - Pyrococcus abyssi (st... 80 5e-14 pir||S77207 hypothetical protein slr1435 - Synechocystis sp. (st... 80 7e-14 sp|P45077|PMBA_HAEIN PMBA PROTEIN HOMOLOG >gi|1075002|pir||C6418... 79 1e-13 sp|P24231|PMBA_ECOLI PMBA PROTEIN (TLDE PROTEIN) >gi|96308|pir||... 75 2e-12 pir||B83086 PmbA protein PA4472 [imported] - Pseudomonas aerugin... 70 4e-11 pir||B69009 conserved hypothetical protein MTH1070 - Methanobact... 69 1e-10 >pir||C75180 tldd related protein PAB1955 - Pyrococcus abyssi (strain Orsay) >gi|5458032|emb|CAB49522.1| (AJ248284) TLDD RELATED PROTEIN [Pyrococcus abyssi] Length = 458 Score = 923 bits (2360), Expect = 0.0 Identities = 458/458 (100%), Positives = 458/458 (100%) Query: 1 MMNMESLEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLAN 60 MMNMESLEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLAN Sbjct: 1 MMNMESLEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLAN 60 Query: 61 GAWGFSSTSDLSKLEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVD 120 GAWGFSSTSDLSKLEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVD Sbjct: 61 GAWGFSSTSDLSKLEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVD 120 Query: 121 IEEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTG 180 IEEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTG Sbjct: 121 IEEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTG 180 Query: 181 KKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGP 240 KKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGP Sbjct: 181 KKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGP 240 Query: 241 IIVGLIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSERYVEGGFGNDKYDDEGVP 300 IIVGLIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSERYVEGGFGNDKYDDEGVP Sbjct: 241 IIVGLIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSERYVEGGFGNDKYDDEGVP 300 Query: 301 VKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEE 360 VKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEE Sbjct: 301 VKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEE 360 Query: 361 MIEDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKI 420 MIEDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKI Sbjct: 361 MIEDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKI 420 Query: 421 SAVGKDFAIETGFCGKGQIAFVSSGGPHMRFDGGIIIG 458 SAVGKDFAIETGFCGKGQIAFVSSGGPHMRFDGGIIIG Sbjct: 421 SAVGKDFAIETGFCGKGQIAFVSSGGPHMRFDGGIIIG 458 >pir||E71033 tldD-related protein PH1557 - Pyrococcus horikoshii >gi|3257986|dbj|BAA30669.1| (AP000006) 458aa long hypothetical protein [Pyrococcus horikoshii] Length = 458 Score = 862 bits (2202), Expect = 0.0 Identities = 417/458 (91%), Positives = 440/458 (96%) Query: 1 MMNMESLEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLAN 60 M+ ME+LEKAL+WAEENIKAEYIELRYED+KRT L LKDGVF +FTEKLNRGVAIRVL N Sbjct: 1 MVPMEALEKALRWAEENIKAEYIELRYEDIKRTALNLKDGVFVNFTEKLNRGVAIRVLVN 60 Query: 61 GAWGFSSTSDLSKLEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVD 120 GAWGFSSTS+L K+EEAIKEAYKLAK ASETKKEKI+LAEIKPVEDFVKSKMK+KPREVD Sbjct: 61 GAWGFSSTSELDKVEEAIKEAYKLAKVASETKKEKIKLAEIKPVEDFVKSKMKIKPREVD 120 Query: 121 IEEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTG 180 IEEK+ HL ELE LLKED+ VKSVNIRYEDGGGQKILLTNEGT+IEWDYNYLWQ VYVTG Sbjct: 121 IEEKINHLKELENLLKEDKAVKSVNIRYEDGGGQKILLTNEGTKIEWDYNYLWQGVYVTG 180 Query: 181 KKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGP 240 K++GKLAMARD+IGAVDYGWELMTEKEPNEKV+DR+LRKLHSQL G+ PKRGEFPVVAGP Sbjct: 181 KEDGKLAMARDTIGAVDYGWELMTEKEPNEKVRDRILRKLHSQLKGITPKRGEFPVVAGP 240 Query: 241 IIVGLIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSERYVEGGFGNDKYDDEGVP 300 IIVG+IAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSER+VEGGFGNDKYDDEGVP Sbjct: 241 IIVGIIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSERHVEGGFGNDKYDDEGVP 300 Query: 301 VKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEE 360 V+DIHIIENGILKEIMLNREYA KFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEE Sbjct: 301 VRDIHIIENGILKEIMLNREYATKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEE 360 Query: 361 MIEDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKI 420 MIEDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKI Sbjct: 361 MIEDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKI 420 Query: 421 SAVGKDFAIETGFCGKGQIAFVSSGGPHMRFDGGIIIG 458 +AVGKDF IE GFCGKGQ AFVSSGGPHMRF+GGIIIG Sbjct: 421 TAVGKDFGIEVGFCGKGQTAFVSSGGPHMRFEGGIIIG 458 >pir||G71248 tldD homolog PH0246 - Pyrococcus horikoshii >gi|3256635|dbj|BAA29318.1| (AP000001) 504aa long hypothetical tldd protein [Pyrococcus horikoshii] Length = 504 Score = 307 bits (777), Expect = 2e-82 Identities = 172/454 (37%), Positives = 271/454 (58%), Gaps = 13/454 (2%) Query: 1 MMNMESLEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLAN 60 ++ ++ + K L+ + + +++++R E ++ T LT+++G + RGV +RVL N Sbjct: 49 LIMIDEILKVLEKYSSSSEIKFMDIRMESIEYTELTIENGKVENLENNGERGVGVRVLIN 108 Query: 61 GAWGFSSTSDLSKLEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVD 120 G WGF+ST+DL+K+EE +K A K+AK + + P+ED V+ K +K +++D Sbjct: 109 G-WGFASTNDLTKIEEIVKTAIKMAK----VSRISTSVYTRDPIEDNVEVKQGIKLKDID 163 Query: 121 IEEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTG 180 +EEKVK E+ +LK E +K+ Y D +K+ L++EG+ IE ++ S+ Sbjct: 164 LEEKVKLGVEVNNMLKR-ENIKTRKFSYSDIIVKKLYLSSEGSIIESTVPRVYLSISSVA 222 Query: 181 KKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGP 240 K GK+ S G GWE++ EK E + + +K S L+ +P GE V+ P Sbjct: 223 KFSGKMQTYWKSFGGTG-GWEIV-EKIDFEHWANFVSKKAVSLLSARSPPSGEMQVIMDP 280 Query: 241 IIVGLIAHEALGHLAEADLTMN--SPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDE 297 + G+ HEALGH +EAD S +LGK+IA E +T+ + + G FG+ YDDE Sbjct: 281 ELAGVFIHEALGHASEADAVKQEESILAGMLGKRIAVEELTVVDDPTLPGKFGSYIYDDE 340 Query: 298 GVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWS 357 G+P K + II +G+L + +RE ++ N+EPNGH RAQ Y + P++RM NT EPGDW Sbjct: 341 GIPGKRVEIIRDGVLVNYLNDRETSSLLNLEPNGHGRAQSYSHVPLVRMSNTYIEPGDWR 400 Query: 358 FEEMIEDIKFGYYLVDFRGGQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEA 416 FEE+++++KFG Y++ +GGQ + S F +EGY++ NGEI +RD +++G + A Sbjct: 401 FEEILDEVKFGVYMIGDKGGQVDVASGNFMFAAKEGYLVENGEIKGHLRDVALSGNILSA 460 Query: 417 LKKISAVGKDFAIE-TGFCGKGQIAFVSSGGPHM 449 L++I A+G D IE GFCGKGQ V GGPH+ Sbjct: 461 LREIKAIGNDLKIEFPGFCGKGQWVPVDDGGPHV 494 >sp|Q58403|Y996_METJA HYPOTHETICAL PROTEIN MJ0996 >gi|2826357|gb|AAB99001.1| (U67542) conserved hypothetical protein [Methanococcus jannaschii] Length = 451 Score = 290 bits (735), Expect = 2e-77 Identities = 174/459 (37%), Positives = 267/459 (57%), Gaps = 23/459 (5%) Query: 1 MMNMESLEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLAN 60 M+N+E +EK L+ +Y ++R + T+TLKDG + GVA+RVL Sbjct: 1 MLNLEKIEKLLE------VGDYADIRINFGESNTITLKDGKIEEISSGFGNGVAVRVLYK 54 Query: 61 GAWGFSSTSDLSK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPRE 118 WGF +++ +S+ +E+ I +AYK+AK ++E +++I L + K + D K K+ P + Sbjct: 55 NGWGFVTSNIVSEEEIEKLINKAYKMAKISNEYSEKEIILKDYKAIIDNYKMIGKINPTD 114 Query: 119 VDIEEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYV 178 VDIEEK + + + K + DE +KS+++ Y D G++I + +EG+RIE + + Sbjct: 115 VDIEEKKEIIIDTYKNMT-DEKIKSISVSYSDVFGKRIFMISEGSRIEGEITRCIMYMNC 173 Query: 179 TGKKEGKLAMARDSIGAVDYGWELMTEKEPNE--KVKDRLLRKLHSQLNGVAPKRGEFPV 236 K+ G L + G +G+E + + N + K+R LR L ++ PK G+F V Sbjct: 174 VAKENGNLQYGAERTGG--FGFEKIKDNYLNLALEAKNRALRLLKAK---PCPK-GKFKV 227 Query: 237 VAGPIIVGLIAHEALGHLAEADLTM--NSPFKDLLGKQIAPEYVTM-SERYVEGGFGNDK 293 + P + G+ HEA+GH +EADL + +S FKD LG+++ EYVT+ + +EG FG+ K Sbjct: 228 ILDPELAGVFIHEAVGHASEADLVLQNDSVFKDKLGERVGSEYVTVIDDATIEGAFGSYK 287 Query: 294 YDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEP 353 YDDEGV K IIENGILK + +RE A + + E G+ RA+ PI+RM NT +P Sbjct: 288 YDDEGVEGKKTVIIENGILKTYLHSRETAGRMDAELTGNGRAEGLN-KPIVRMSNTFIKP 346 Query: 354 GDWSFEEMIEDIKFGYYLVDFRGGQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGV 412 GDWSFEE++ED K G +L RGGQ FQ E Y+I NGE+ + ++D ++G Sbjct: 347 GDWSFEELLEDTKEGIFLKGSRGGQVDTGKGLFQFSAVEAYLIENGELTQVLKDAGLSGE 406 Query: 413 AIEALKKISAVGKDFAIETGFCGK-GQIAFVSSGGPHMR 450 ++ L K+ AV KDF + G+CGK GQ V GG +R Sbjct: 407 ILDILFKVDAVTKDFELSVGYCGKDGQSVPVGDGGGCVR 445 >pir||A75213 tldd protein PAB0154 - Pyrococcus abyssi (strain Orsay) >gi|5457661|emb|CAB49152.1| (AJ248283) TLDD PROTEIN [Pyrococcus abyssi] Length = 452 Score = 290 bits (735), Expect = 2e-77 Identities = 167/436 (38%), Positives = 253/436 (57%), Gaps = 13/436 (2%) Query: 19 KAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAI 78 + +++++R+E+ T T+++G G+ +RVL NG WGF+ST+DLSKLE+ I Sbjct: 15 EVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFASTNDLSKLEDTI 73 Query: 79 KEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLTELEKLLKED 138 K A KLAK ++ ++ L PVE K K +VD+EEK K E+EK+++ D Sbjct: 74 KMAIKLAKVSNA----EVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRD 129 Query: 139 ETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGAVDY 198 + +K+ Y D +KI L +EG+ IE ++ S+ + + S G Sbjct: 130 K-IKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGT-V 187 Query: 199 GWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAEAD 258 GWEL+ + N + + K S L+ +P GE P++ P + G+ HEALGH EAD Sbjct: 188 GWELVESVDFNYWA-NFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEAD 246 Query: 259 LTMN--SPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPVKDIHIIENGILKEI 315 S ++GK+I E +T+ + + G FG+ YDDEG+P K + II++G+L Sbjct: 247 SVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNY 306 Query: 316 MLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFR 375 + +RE + N+ PNGH RAQ Y + P++RM NT PG+W+ EEM E++KFG Y++ + Sbjct: 307 LNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDK 366 Query: 376 GGQAQL-NSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAIE-TGF 433 GGQ + N +F G +EGY+I+ GEI E +RD I+G ++ LK+I AVG+D IE GF Sbjct: 367 GGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFPGF 426 Query: 434 CGKGQIAFVSSGGPHM 449 CGKGQ V GGPH+ Sbjct: 427 CGKGQWVPVDDGGPHV 442 >pir||D64424 tldD homolog MJ0996 - Methanococcus jannaschii Length = 451 Score = 288 bits (730), Expect = 7e-77 Identities = 173/459 (37%), Positives = 266/459 (57%), Gaps = 23/459 (5%) Query: 1 MMNMESLEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLAN 60 M+N+E +EK L+ +Y ++R + T+TLKDG + GVA+RVL Sbjct: 1 MLNLEKIEKLLE------VGDYADIRINFGESNTITLKDGKIEEISSGFGNGVAVRVLYK 54 Query: 61 GAWGFSSTSDLSK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPRE 118 WGF +++ +S+ +E+ I +AYK+AK ++E +++ L + K + D K K+ P + Sbjct: 55 NGWGFVTSNIVSEEEIEKLINKAYKMAKISNEYSEKEXILKDYKAIIDNYKMIGKINPTD 114 Query: 119 VDIEEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYV 178 VDIEEK + + + K + DE +KS+++ Y D G++I + +EG+RIE + + Sbjct: 115 VDIEEKKEIIIDTYKNMT-DEKIKSISVSYSDVFGKRIFMISEGSRIEGEITRCIMYMNC 173 Query: 179 TGKKEGKLAMARDSIGAVDYGWELMTEKEPNE--KVKDRLLRKLHSQLNGVAPKRGEFPV 236 K+ G L + G +G+E + + N + K+R LR L ++ PK G+F V Sbjct: 174 VAKENGNLQYGAERTGG--FGFEKIKDNYLNLALEAKNRALRLLKAK---PCPK-GKFKV 227 Query: 237 VAGPIIVGLIAHEALGHLAEADLTM--NSPFKDLLGKQIAPEYVTM-SERYVEGGFGNDK 293 + P + G+ HEA+GH +EADL + +S FKD LG+++ EYVT+ + +EG FG+ K Sbjct: 228 ILDPELAGVFIHEAVGHASEADLVLQNDSVFKDKLGERVGSEYVTVIDDATIEGAFGSYK 287 Query: 294 YDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEP 353 YDDEGV K IIENGILK + +RE A + + E G+ RA+ PI+RM NT +P Sbjct: 288 YDDEGVEGKKTVIIENGILKTYLHSRETAGRMDAELTGNGRAEGLN-KPIVRMSNTFIKP 346 Query: 354 GDWSFEEMIEDIKFGYYLVDFRGGQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGV 412 GDWSFEE++ED K G +L RGGQ FQ E Y+I NGE+ + ++D ++G Sbjct: 347 GDWSFEELLEDTKEGIFLKGSRGGQVDTGKGLFQFSAVEAYLIENGELTQVLKDAGLSGE 406 Query: 413 AIEALKKISAVGKDFAIETGFCGK-GQIAFVSSGGPHMR 450 ++ L K+ AV KDF + G+CGK GQ V GG +R Sbjct: 407 ILDILFKVDAVTKDFELSVGYCGKDGQSVPVGDGGGCVR 445 >emb|CAB57642.1| (Y18930) hypothetical protein [Sulfolobus solfataricus] Length = 443 Score = 249 bits (630), Expect = 4e-65 Identities = 159/449 (35%), Positives = 243/449 (53%), Gaps = 25/449 (5%) Query: 9 KALKWAEENIKAEYIELRYEDLKRTTLTL-KDGVFTSFTEKLNRGVAIRVLANGAWGFSS 67 K +K AEE + A + ++RYE + +T+ +D + S ++ G +IRV+ N WGF + Sbjct: 3 KYIKKAEE-LGASFADIRYERVIANEVTITEDRKYVS--HGVDEGYSIRVIYNRNWGFKA 59 Query: 68 TSDLSK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKV 125 T +++ +E+ I Y E++ + + D +K + E EEK+ Sbjct: 60 TDKITENEIEDTINHIYG---------DERVNIVYLPSKHDTIKIGKDINKNE---EEKI 107 Query: 126 KHLTELEKLLKE-DETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEG 184 L ++ + ++KS +I+Y D K ++E I D + S+ V + EG Sbjct: 108 NDLHKVASQVNTLHPSIKSYSIKYYDEIFHKEYYSSEDREIIADGSSSSLSILVVAR-EG 166 Query: 185 KLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVG 244 + + I + G+ + + +V L +++ +QL G PK GE+PV+ P +VG Sbjct: 167 DVTVEVSEILSTQMGY--IFDVFDINQVLANLQKRIINQLKGSTPKAGEYPVILAPEVVG 224 Query: 245 LIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSERYVEGGFGNDK--YDDEGVPVK 302 + HEA+GHL+EAD+T+N L K+I E++ +S+ + YDDEGV + Sbjct: 225 IFTHEAIGHLSEADVTLNGSLYKLRNKRIGDEFLNISDLPAMDHPQSSLVYYDDEGVEGR 284 Query: 303 DIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMI 362 ++ IIENGILKE M +R Y+A P G+ARAQ YR +IRMRNT +PGD S E+ Sbjct: 285 EVKIIENGILKEFMTDRYYSAYLGQPPTGNARAQSYRNFSLIRMRNTYMKPGDASLNELF 344 Query: 363 EDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISA 422 E IK GYYLV GG+ N FQ IQEGY + N EI EP+R+ I+G I L I Sbjct: 345 EGIKEGYYLVSPIGGETSSNGTFQFAIQEGYRVENSEIKEPLRNIGISGNTISTLNAIEM 404 Query: 423 VGKDFAIETGFCGK-GQIAFVSSGGPHMR 450 + KDF + +GFC K GQ VS+GGPH++ Sbjct: 405 ISKDFGMSSGFCEKNGQTVQVSNGGPHIK 433 >gb|AAK40965.1| Zn-dependent protease, tldD protein homolog, putative (tldD) [Sulfolobus solfataricus] Length = 443 Score = 249 bits (630), Expect = 4e-65 Identities = 159/449 (35%), Positives = 243/449 (53%), Gaps = 25/449 (5%) Query: 9 KALKWAEENIKAEYIELRYEDLKRTTLTL-KDGVFTSFTEKLNRGVAIRVLANGAWGFSS 67 K +K AEE + A + ++RYE + +T+ +D + S ++ G +IRV+ N WGF + Sbjct: 3 KYIKKAEE-LGASFADIRYERVIANEVTITEDRKYVS--HGVDEGYSIRVIYNRNWGFKA 59 Query: 68 TSDLSK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKV 125 T +++ +E+ I Y E++ + + D +K + E EEK+ Sbjct: 60 TDKITENEIEDTINHIYG---------DERVNIVYLPSKHDTIKIGKDINKNE---EEKI 107 Query: 126 KHLTELEKLLKE-DETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEG 184 L ++ + ++KS +I+Y D K ++E I D + S+ V + EG Sbjct: 108 NDLHKVASQVNTLHPSIKSYSIKYYDEIFHKEYYSSEDREIIADGSSSSLSILVVAR-EG 166 Query: 185 KLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVG 244 + + I + G+ + + +V L +++ +QL G PK GE+PV+ P +VG Sbjct: 167 DVTVEVSEILSTQMGY--IFDVFDINQVLANLQKRIINQLKGSTPKAGEYPVILAPEVVG 224 Query: 245 LIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSERYVEGGFGNDK--YDDEGVPVK 302 + HEA+GHL+EAD+T+N L K+I E++ +S+ + YDDEGV + Sbjct: 225 IFTHEAIGHLSEADVTLNGSLYKLRNKRIGDEFLNISDLPAMDHPQSSLVYYDDEGVEGR 284 Query: 303 DIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMI 362 ++ IIENGILKE M +R Y+A P G+ARAQ YR +IRMRNT +PGD S E+ Sbjct: 285 EVKIIENGILKEFMTDRYYSAYLGQPPTGNARAQSYRNFSLIRMRNTYMKPGDASLNELF 344 Query: 363 EDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISA 422 E IK GYYLV GG+ N FQ IQEGY + N EI EP+R+ I+G I L I Sbjct: 345 EGIKEGYYLVSPIGGETSSNGTFQFAIQEGYRVENSEIKEPLRNIGISGNTISTLNAIEM 404 Query: 423 VGKDFAIETGFCGK-GQIAFVSSGGPHMR 450 + KDF + +GFC K GQ VS+GGPH++ Sbjct: 405 ISKDFGMSSGFCEKNGQTVQVSNGGPHIK 433 >sp|O26944|Y856_METTH HYPOTHETICAL PROTEIN MTH856 >gi|7429832|pir||C69214 zinc metalloproteinase - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621948|gb|AAB85354.1| (AE000862) zinc metalloproteinase [Methanobacterium thermoautotrophicum] Length = 454 Score = 239 bits (603), Expect = 6e-62 Identities = 152/444 (34%), Positives = 228/444 (51%), Gaps = 12/444 (2%) Query: 19 KAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAI 78 + EY ++R + +++ +KDG G IRVL NG+WGF+ T + S+L E Sbjct: 18 RVEYADIRAGTSRTSSILMKDGKLQEVKSGRASGFRIRVLRNGSWGFAFTDEPSRLGEMA 77 Query: 79 KEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLTELEKLLKED 138 +A K+ S + +++ P D + P +V EK + +++ D Sbjct: 78 LKAIKMTGSL----RGDVQVGSGAPSVDKTMVRSSRPPSDVPAAEKRELVSDAHHAASVD 133 Query: 139 ETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGAVDY 198 V S + Y D L +EG+ IE + + + S G Sbjct: 134 GVV-STTVSYVDMESSSAFLNSEGSLIEMAETRVALFLNAVASDGSGIQFGHKSCGGTG- 191 Query: 199 GWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAEAD 258 G+E++ E+E E++ R K L P G F +V P + G+ HEALGH AEAD Sbjct: 192 GFEIL-EREDIEELGRRTGEKAVRLLKASPPPSGRFDIVTDPELTGVFIHEALGHAAEAD 250 Query: 259 LTM--NSPFKDLLGKQIAPEYVTMSERYVEGGFGNDKYDDEGVPVKDIHIIENGILKEIM 316 L + +S + LG++IA E VT+ + GFG+ YD EGV + ++ENG+L ++ Sbjct: 251 LILQGDSILEGKLGEKIASEGVTIIDDPTIDGFGSYSYDAEGVRAAETVLVENGVLTSLL 310 Query: 317 LNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFRG 376 +RE A K +EP+G+AR+ PI+RM NT +PGD SF+E+IEDI+ G YL RG Sbjct: 311 NSRETAFKLGLEPSGNARSA-IGDQPIVRMSNTYLKPGDLSFDELIEDIRNGVYLRGSRG 369 Query: 377 GQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAIETGFCG 435 GQ FQ E + I++GEIAEP++D S++G +E LK + VG DF + GFCG Sbjct: 370 GQVDTGKGIFQFNAAESFRIQDGEIAEPVKDVSLSGNVLETLKNVDGVGSDFRLGIGFCG 429 Query: 436 K-GQIAFVSSGGPHMRFDGGIIIG 458 K GQ V GGPH+R ++ G Sbjct: 430 KSGQSVPVGDGGPHVRIRNAMVGG 453 >pir||G75033 hypothetical protein PAB1547 - Pyrococcus abyssi (strain Orsay) >gi|5458677|emb|CAB50164.1| (AJ248287) hypothetical protein [Pyrococcus abyssi] Length = 473 Score = 232 bits (586), Expect = 6e-60 Identities = 159/462 (34%), Positives = 239/462 (51%), Gaps = 22/462 (4%) Query: 6 SLEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGF 65 ++EKAL+ + A Y E R+E+ + T+L++K+GV +RG+ IRVL +G GF Sbjct: 8 AVEKALE-----LGANYAEARFEEKQGTSLSMKNGVPQGMQLLSDRGIGIRVLVDGGMGF 62 Query: 66 SSTSDLSK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEE 123 +ST+ L+K + E ++ A KLAKSAS+ +KE I+ ++ + + KMK R+V EE Sbjct: 63 ASTNILTKESIVETVQRAVKLAKSASKLRKEPIKFSDEYFHNVYYEVKMKKDFRDVPPEE 122 Query: 124 KVKHLTELEK-LLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKK 182 K++ L ++E+ +L + V + Y D KI + +E +E + + + Sbjct: 123 KLELLKKIEEEVLSTNVKVPMRYLAYSDHVWHKIFVNSENAVVESVIPRVSVMYNLVVYE 182 Query: 183 EGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPII 242 EG++ A A G EL+ + EP E+ K + G P G+ +V P + Sbjct: 183 EGQMEQAPFVSRAFSGGLELIEKDEPWERAKKEVETLKRIITEGKKPPEGKVDLVISPEV 242 Query: 243 VGLIAHEALGHLAEADLTMNSPFK---------DLLGKQIAPEYVTM-SERYVEGGFGND 292 G+ HE++GH E D M D+LG++I E VT+ + + +G Sbjct: 243 AGIAVHESVGHPYELDRIMGREAAQAGESFVKPDMLGERIGSEVVTVIDDPTIPNSWGFY 302 Query: 293 KYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFE 352 YDDEGV + ++I NGI+ E ++NREYAAK + N ARA +Y PI+RM NT Sbjct: 303 LYDDEGVKARPRYLIRNGIITEFLMNREYAAKLGLRSNAAARAINYNREPIVRMANTYLA 362 Query: 353 PGDWSFEEMIEDIKFGYYLVDFRGGQAQLNSAFQVGI-QEGYVIRNGEIAEPIRDTSITG 411 PGD+SFEE+IEDIK G Y+V F Q I +E Y+I NGEI P++ + Sbjct: 363 PGDYSFEELIEDIKLGVYMVSFNEWNIDDRRYQQRYIGREAYLIENGEIKHPVKRPILEI 422 Query: 412 VAIEALKKISAVGKDFAIETGFCGK---GQIAFVSSGGPHMR 450 + AVGK+ G CGK GQ V GG H R Sbjct: 423 TTRGLWSSVDAVGKEVEFHPGTCGKGEPGQGVPVWMGGAHAR 464 >pir||D71135 tldD-related protein PH0848 - Pyrococcus horikoshii >gi|3257259|dbj|BAA29942.1| (AP000003) 481aa long hypothetical protein [Pyrococcus horikoshii] Length = 481 Score = 228 bits (576), Expect = 8e-59 Identities = 160/466 (34%), Positives = 241/466 (51%), Gaps = 32/466 (6%) Query: 11 LKWAEEN---IKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSS 67 L++A EN + A Y E R+E+ + +L +K+G+ ++G+ +RVL NG GF+S Sbjct: 13 LEFAIENALELGASYAEARFEEKQGISLAMKNGIPEGMEILSDKGIGVRVLVNGGMGFAS 72 Query: 68 TSDLSK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKV 125 T+ L+K + E +K A KLAK+AS+ +KE I +E + + KMK R+V EEK+ Sbjct: 73 TNVLTKESIAETVKRAVKLAKAASKLRKEPITFSEEDFHNVYYEVKMKKDFRDVSPEEKL 132 Query: 126 KHLTELEKLLKEDETVKSVN-----IRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTG 180 EL K ++E+ T +VN I Y D K+ + +E +IE + + Sbjct: 133 ----ELLKKIEEEVTSTNVNVPMRYIAYSDHVWHKVFMNSENAKIESLIPRVSVMYNLVV 188 Query: 181 KKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRL--LRKLHSQLNGVAPKRGEFPVVA 238 + G++ A A G EL+ + EP E+ K + LRK+ ++ G G+ V+ Sbjct: 189 FENGQMEQAPFIQRAFSGGLELIEKDEPWERAKREVETLRKIITE--GKRSPEGKVDVII 246 Query: 239 GPIIVGLIAHEALGHLAEADLTMNSPFK---------DLLGKQIAPEYVTM-SERYVEGG 288 P + G+ HE++GH E D M ++LG++I E VT+ + + Sbjct: 247 SPEVAGIAVHESVGHPYELDRIMGREAAQAGESFVKPEMLGERIGSEVVTVIDDPTIPNS 306 Query: 289 FGNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRN 348 +G YDDEGV + ++I NGI+ E ++NREYAAK + N ARA +Y PI+RM N Sbjct: 307 WGFYLYDDEGVKARPRYLIRNGIITEFLMNREYAAKLGLRSNAAARAINYNREPIVRMAN 366 Query: 349 TVFEPGDWSFEEMIEDIKFGYYLVDFRGGQAQLNSAFQVGI-QEGYVIRNGEIAEPIRDT 407 T PGD+SFEE+IED+K G Y+V F Q I +E Y+I NGEI P++ Sbjct: 367 TYLAPGDYSFEELIEDVKLGVYMVSFNEWNIDDRRYQQRYIGREAYLIENGEIKHPVKRP 426 Query: 408 SITGVAIEALKKISAVGKDFAIETGFCGK---GQIAFVSSGGPHMR 450 + + AVGK+ G CGK GQ V GG H R Sbjct: 427 ILEITTRGLWSSVDAVGKEVEFYAGTCGKGEPGQGVPVWMGGAHAR 472 >pir||D72762 hypothetical protein APE0089 - Aeropyrum pernix (strain K1) >gi|5103477|dbj|BAA78998.1| (AP000058) 489aa long hypothetical protein [Aeropyrum pernix] Length = 489 Score = 194 bits (487), Expect = 2e-48 Identities = 152/469 (32%), Positives = 237/469 (50%), Gaps = 37/469 (7%) Query: 7 LEKALKWAEENIKAEYIELRYED-LKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGF 65 LEK ++ A + A Y E R+ L + L + D V E + GVA RV+ +GA GF Sbjct: 26 LEKLVEKALDK-GASYAEARFHARLGDSVLVVNDRVVGGGFE-IEEGVAFRVIVDGALGF 83 Query: 66 SSTSDLSK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEE 123 +STS LS+ L+ + A +A+S+S ++K+ ++E + + K+K R +++E+ Sbjct: 84 ASTSLLSEESLDSVVDHAVSIARSSSRGFRKKVGMSEERLGQAQYSLKVKKDFRNLELED 143 Query: 124 KVKHLTELEKLLKEDET-VKSVNIRYEDGGGQKILLTNEGTRIEWD-------YNYLWQS 175 K + E K L+ +K+ Y D K+++T++G IE YN + Sbjct: 144 KASIVLEYSKSLESKSVDLKAKTFSYSDVLEAKLIITSDGGNIESIIPRVSIFYNIAAEH 203 Query: 176 VYVTGKKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFP 235 K G LA + G EL+ E +KD + + + +G Sbjct: 204 GDRRANKWGHLAGSG--------GLELVGELGLESMLKDDVNSLEVNLVKAEPSPKGVMD 255 Query: 236 VVAGPIIVGLIAHEALGHLAEADLTMNSP-------FKDLLGKQIAPEYVTMSER-YVEG 287 V+ P IVGL HE++GH +EAD M ++ L +I VT+++ V G Sbjct: 256 VIISPEIVGLALHESIGHPSEADRVMGREAAQAGLSYRMWLDGRIGSSKVTVADDPTVPG 315 Query: 288 GFGNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMR 347 +G YDDE VP ++ +I G L E++ +R A F ++ NG ARA +YR PI+RM Sbjct: 316 SYGFYLYDDEAVPARERILINKGELAELLHSRTTAYSFGVQSNGAARAMNYRSEPIVRMS 375 Query: 348 NTVFEPGDWSFEEMIEDIKFGYYL---VDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPI 404 NT +PGD FEE++ED+K G Y+ +++ + +L + + VG+ E Y+I+NG I +P+ Sbjct: 376 NTYLKPGDMRFEELLEDVKEGIYMKSYMEWNIDEFRLVARY-VGL-EAYLIKNGRIVKPV 433 Query: 405 RDTSITGVAIEALKKISAVGKDFAIETGFCGKG---QIAFVSSGGPHMR 450 RDT + KI VGKD G CGKG Q V GGPH+R Sbjct: 434 RDTVLEIPTESFYSKIDGVGKDLRFYAGICGKGEPPQPLPVWMGGPHVR 482 >sp|P73754|Y863_SYNY3 HYPOTHETICAL 50.4 KD PROTEIN SLR0863 >gi|7429837|pir||S74845 tldD homolog slr0863 - Synechocystis sp. (strain PCC 6803) >gi|1652888|dbj|BAA17806.1| (D90909) hypothetical protein [Synechocystis sp.] Length = 463 Score = 192 bits (482), Expect = 9e-48 Identities = 131/450 (29%), Positives = 226/450 (50%), Gaps = 19/450 (4%) Query: 19 KAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAI 78 +A++I +R E + T ++L+ + +E + G +RV G WGF+S + +L + + Sbjct: 20 QADFISIRLEQSEGTQISLRSDQVETLSEGIAMGGQVRVCHQGGWGFASFNRWEQLRQRL 79 Query: 79 KEAYKLAKSASETKKEKIELAEIKPVED-FVKSKMKVKPREVDIEEKVKHLTELEKLLK- 136 +EA A+ + ++ LA I PV+ F+ PR++ + +K LL+ Sbjct: 80 EEAIAAARLIGD---DETLLAPIDPVQQTFINPLTGKDPRQISLADKKALCDHYNDLLRG 136 Query: 137 EDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGAV 196 + + + ++RY D +L T+EGT +E + L T K + + R++ G+ Sbjct: 137 TSDKITTTHVRYSDSQQTVLLATSEGTLLEQCWWDLEMRFAATAKDGNGVQVGRETTGSR 196 Query: 197 -DYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLA 255 YG + E ++V ++ L + +PVV PI+ GL HEA GHL+ Sbjct: 197 RGYG-----DLENLDQVVQGAAQRAVKALTLPTVQGKTYPVVIDPILTGLFVHEAFGHLS 251 Query: 256 EADLTMNSP-FKDL--LGKQIAPEYVTMSERYVEGGF-GNDKYDDEGVPVKDIHIIENGI 311 EAD+ +P F ++ LG++ P + + + G G+ +DDEGVP +I++G Sbjct: 252 EADMLYENPDFLEVMSLGRRFGPPELQIFDGAAPPGHRGSYGFDDEGVPASTTQLIKDGE 311 Query: 312 LKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYL 371 L + +RE A K +P G+AR +Y YPPI+RM NT G+ +++ I+ G Y Sbjct: 312 LVGRLHSRETAGKLGEKPTGNARCLNYHYPPIVRMTNTWIGRGETPVANLLDGIEEGIYA 371 Query: 372 VDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFA-IE 430 ++ GG F E ++IR+G++AEP++D +++G + L I A+ DF E Sbjct: 372 QNWLGGMTN-GEMFTFSAGEAWMIRHGQLAEPVKDVTLSGNVFKTLANIEAIADDFYWDE 430 Query: 431 TGFCGKG--QIAFVSSGGPHMRFDGGIIIG 458 +G CGKG V GGP +R ++ G Sbjct: 431 SGGCGKGGQNGLAVGCGGPSLRIRDVVVGG 460 >gi|11498263 conserved hypothetical protein [Archaeoglobus fulgidus] >gi|3123065|sp|O29602|Y655_ARCFU HYPOTHETICAL PROTEIN AF0655 >gi|7429834|pir||G69331 conserved hypothetical protein AF0655 - Archaeoglobus fulgidus >gi|2649963|gb|AAB90585.1| (AE001059) conserved hypothetical protein [Archaeoglobus fulgidus] Length = 425 Score = 180 bits (451), Expect = 4e-44 Identities = 134/436 (30%), Positives = 223/436 (50%), Gaps = 35/436 (8%) Query: 25 LRYEDLKRT-----TLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAIK 79 +R+ D++R L L++G + RVL NG WG + +E ++ Sbjct: 1 MRFWDIRRVENVSLNLQLENGKLEKPRYNKSTSKGFRVLKNGFWGIFEGNVAD--DEGLR 58 Query: 80 EAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLTELEKLLKEDE 139 +A K A + + E+I + + ++K P+++ IEEKV+ L +LEK+++ D Sbjct: 59 QAEKNAFTQGDGDIEEIA------TKGRYRMRVKRDPQDMSIEEKVELLKDLEKIIR-DV 111 Query: 140 TVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGK----LAMARDSIGA 195 V + + +E+ +++L + E +Y L V + G +G+ L+ + +G Sbjct: 112 CVSTKLVYFEN---RRVLQYRDSCGSEVEYEVLRTGVSIMGVGKGRSLQFLSKRQMRVG- 167 Query: 196 VDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLA 255 G+E++ + +L KL +N +AP GE VV + G+ HEA GH Sbjct: 168 ---GYEVLDGVDEKAYEIVEVLPKL---VNALAPPSGEMSVVMDSSLAGVFVHEAFGHAV 221 Query: 256 EADLTMNSP--FKDLLGKQIAPEYVTMSERYVEGGFGNDKYDDEGVPVKDIHIIENGILK 313 EAD + K L +++A E VT+ + FG +DDEGV + I+E+G+LK Sbjct: 222 EADHVLQGATVLKGRLNEKVADESVTIIDDPTLPEFGFFPFDDEGVRAEKKVIVEDGVLK 281 Query: 314 EIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVD 373 + +RE A K G+AR+Q P I+RM NT + +SF+E++E+ + G YLV Sbjct: 282 SFLHSRETAKKLGGVA-GNARSQGVDVP-IVRMSNTYIDTHHYSFDELLEECRDGVYLVG 339 Query: 374 FRGGQAQ-LNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAIETG 432 RGG+ F Q GY+I+NGE+AE +RD S++G +E L+ + +G++ + G Sbjct: 340 SRGGETNPATGYFHFNAQYGYLIKNGELAEMVRDVSLSGNTLEILRNVK-IGREIEFDPG 398 Query: 433 FCGK-GQIAFVSSGGP 447 FCGK GQ+ VS G P Sbjct: 399 FCGKAGQLVPVSDGSP 414 >sp|P46473|TLDD_ECOLI TLDD PROTEIN >gi|7429829|pir||F65116 tldD protein - Escherichia coli (strain K-12) >gi|606183|gb|AAA58046.1| (U18997) ORF_f481 [Escherichia coli] >gi|1732437|dbj|BAA07913.1| (D44451) TldD protein [Escherichia coli] >gi|1789640|gb|AAC76276.1| (AE000403) suppresses inhibitory activity of CsrA [Escherichia coli K12] Length = 481 Score = 159 bits (399), Expect = 5e-38 Identities = 123/448 (27%), Positives = 210/448 (46%), Gaps = 20/448 (4%) Query: 19 KAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLS--KLEE 76 + +Y +L ++ + L+D + + +++GV +R ++ GF+ +S LE+ Sbjct: 32 RLDYGDLYFQSSYHESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYADQISLLALEQ 91 Query: 77 AIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLTELEKLLK 136 + + A + + + + K + + E P+ V + EEK+ L ++K+ + Sbjct: 92 SAQAARTIVRDSGDGKVQTLGAVEHSPLYTSVDPLQSMSR-----EEKLDILRRVDKVAR 146 Query: 137 E-DETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGA 195 E D+ V+ V ++ +GT + SV V +++GK G Sbjct: 147 EADKRVQEVTASLSGVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGASG-GG 205 Query: 196 VDYGWELMTEKEPNEKVKD----RLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEAL 251 +G+E E D +R L+ VA G PVV G G++ HEA+ Sbjct: 206 GRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSAVAAPAGTMPVVLGAGWPGVLLHEAV 265 Query: 252 GHLAEADLTMN--SPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPVKDIHIIE 308 GH E D S F +G+ +A E T+ + + G+ DDEG P + +IE Sbjct: 266 GHGLEGDFNRRGTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQYNVLIE 325 Query: 309 NGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFG 368 NGILK M ++ A M P G+ R + Y + P+ RM NT PG + +E+IE +++G Sbjct: 326 NGILKGYMQDKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYG 385 Query: 369 YYLVDFRGGQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDF 427 Y +F GGQ + S F E Y+I NG++ +P++ ++ G IE +++IS VG D Sbjct: 386 IYAPNFGGGQVDITSGKFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDL 445 Query: 428 AIE--TGFCGK-GQIAFVSSGGPHMRFD 452 ++ G CGK GQ V G P ++ D Sbjct: 446 KLDNGVGVCGKEGQSLPVGVGQPTLKVD 473 >gb|AAK41402.1| Conserved hypothetical protein [Sulfolobus solfataricus] Length = 458 Score = 158 bits (395), Expect = 1e-37 Identities = 123/454 (27%), Positives = 219/454 (48%), Gaps = 35/454 (7%) Query: 16 ENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSD----L 71 + + Y+E+R + ++ +G + G ++R +G F+S+++ L Sbjct: 9 DKFRYPYVEVRRHIVSTFGMSFLNGRLMGSFRFTDDGYSVRYYKDGVLYFASSNNPNDLL 68 Query: 72 SKLEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLTEL 131 S +E E ++ +E K+ E+ E KP + + ++EK+ L Sbjct: 69 SSNKEYKIEGWESGLDNTEPKEGSYEVKEGKPFD------------LMSVDEKISFFKNL 116 Query: 132 EKLLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARD 191 + +K+ +VKSV+ Y++ +K ++ N G+RI L+ + + + + A A Sbjct: 117 YEAVKDFRSVKSVSFFYDESIEEKEIIVN-GSRIVGRVPRLYVGMNLVLNENNRTATAFY 175 Query: 192 SIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEAL 251 +G G E++ NE V D++ G + VV ++ G++AHE++ Sbjct: 176 ELGGSG-GLEVLERMNLNEVVVDKVRSVTEVLAKGKSFGERTTDVVLSNMLTGIMAHESV 234 Query: 252 GHLAEADLTMNSPFK--------DLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPVK 302 GH EAD + F +L +I + VT+ + + G DDEGV + Sbjct: 235 GHPFEADRVLGREFAQAGLSYLAELKDNRIGSDVVTVIDDPTIPNSGGYYTTDDEGVEAR 294 Query: 303 DIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMI 362 ++I++G + E + NR ++KFN++ NG ARA ++ P+IRM NT F+PG+ +F+E++ Sbjct: 295 PKYLIKDGKVNEYLQNRFSSSKFNVKSNGSARAANFDREPLIRMSNTFFKPGNMTFDELL 354 Query: 363 EDIKFGYYL---VDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKK 419 ED+K G Y+ +++ +L + VG+ E Y I+NG+I +P+ G E LK Sbjct: 355 EDVKEGVYIKSYMEWNIDDMRLGQRY-VGL-EAYEIKNGKIGDPVLFPVFQGKTTELLKA 412 Query: 420 ISAVGKDFAIETGFCGKG---QIAFVSSGGPHMR 450 + AV G CGKG Q V GGP+MR Sbjct: 413 VDAVDNTLVFYPGTCGKGDPDQGIPVWLGGPNMR 446 >sp|P57478|TLDD_BUCAI TLDD PROTEIN HOMOLOG >gi|10039067|dbj|BAB13101.1| (AP001119) tldD protein [Buchnera sp. APS] Length = 483 Score = 153 bits (384), Expect = 3e-36 Identities = 123/454 (27%), Positives = 209/454 (45%), Gaps = 22/454 (4%) Query: 21 EYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLS--KLEEAI 78 +Y +L ++ + L++ + + G+ +R + + GF+ + +S L + Sbjct: 34 DYGDLYFQSHIHESWILENSIIKEGNYHSDAGIGVRAIRGESTGFAYSDQISLDSLRRST 93 Query: 79 KEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPRE-VDIEEKVKHLTELEKLLKE 137 K+A+ + + K + + I+P+ V P E +EK L + + Sbjct: 94 KKAHSIILTKGSGKTKTLSKKTIEPIYK------NVNPLEGFSSKEKTDLLYRANYIARS 147 Query: 138 -DETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGA- 195 D V VN Q ++ + +G + + S+ V + GK R G+ Sbjct: 148 LDHRVIEVNASLTGSYEQILVASTDGNLVSDIRPSIQFSISVLVEDHGKRERGRSGGGSR 207 Query: 196 VDYGWELMTEKEPNEKVKDR----LLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEAL 251 DY + L + E D +R L+ G FPVV G G++ HEA+ Sbjct: 208 TDYNFFLNQDDSSKEIRIDHWSKEAVRIALLNLSSKEALSGTFPVVLGSGWPGVLLHEAI 267 Query: 252 GHLAEADLTMN--SPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPVKDIHIIE 308 GH E D S F +++GK++A E T+ + ++ G+ DDEG P + +IE Sbjct: 268 GHGLEGDFNRKGTSIFTNMIGKKVASELCTIIDDGTIKNQRGSLSIDDEGTPGQKNILIE 327 Query: 309 NGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFG 368 NGILK+ M ++ A ++ G+ R + Y P+ RM NT G +++I+ + +G Sbjct: 328 NGILKKYMQDKLNARLMGVKSTGNGRRESYSCLPMPRMTNTYMLSGKSKLDDIIKSVDYG 387 Query: 369 YYLVDFRGGQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDF 427 Y V+F GGQ + S F E Y+I+NG+I PI++T++ G +E ++KIS VG D Sbjct: 388 IYAVNFSGGQVDITSGKFVFSTSEAYLIKNGKIVTPIKNTTLIGSGLEVMQKISMVGDDL 447 Query: 428 AIE--TGFCGK-GQIAFVSSGGPHMRFDGGIIIG 458 ++ G CGK GQ V G P M+ + I G Sbjct: 448 KMDEGMGICGKDGQNIPVGIGQPSMKLENLTIGG 481 >pir||D72342 tldD protein - Thermotoga maritima (strain MSB8) >gi|4981251|gb|AAD35808.1|AE001743_10 (AE001743) tldD protein [Thermotoga maritima] Length = 499 Score = 153 bits (382), Expect = 5e-36 Identities = 121/426 (28%), Positives = 190/426 (44%), Gaps = 21/426 (4%) Query: 21 EYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAIKE 80 ++ EL +E LKDG T GV IR ++ T+DLS+ E I Sbjct: 57 DFAELFFERKYENRYELKDGKIEQATSGEIVGVGIRGFLGTKAVYAYTNDLSR-ENLINV 115 Query: 81 AYKLAKSASETKKEKIELAEIKPVEDFVKSKMK------VKPREVDIEEKVKHLTELEKL 134 A K+ ++ ETK E + +F ++K K + P +V+ +KV + + Sbjct: 116 AKKVGEALGETKVEDLTF-------NFNRTKRKERHVVLIPPAQVEKTDKVSVMKKAYYA 168 Query: 135 LKE-DETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSI 193 K E +K V + Y D + ++ +EGT E + +K+G L Sbjct: 169 AKNYSELIKQVVVWYWDYDQEILVANSEGTWAEDRRVRTRLMINAVAEKDGVLERGFYGP 228 Query: 194 GAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGH 253 GA G+E + E K + R + G+ VV G+I HEA+GH Sbjct: 229 GA-GMGFEFFDRIDVEEAAK-KAARIAARMVEAEPAPAGKMTVVIANGFGGVIFHEAVGH 286 Query: 254 LAEADLTMN--SPFKDLLGKQIAPEYVT-MSERYVEGGFGNDKYDDEGVPVKDIHIIENG 310 EA S F LG+++A E V+ + + + G+G+ DDEG P + +I+ G Sbjct: 287 GLEATSVAKGASVFAGKLGQKVAAECVSAVDDATIPNGWGSANVDDEGTPTQRTLLIDKG 346 Query: 311 ILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYY 370 +L ++++ + M+ G R QDY +PP RM NT PGD+ EE+I ++G Y Sbjct: 347 VLVGYLVDKLGERRMGMKSTGSGRRQDYTFPPTSRMSNTFILPGDYHPEEIIAATEYGLY 406 Query: 371 LVDFRGGQAQ-LNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAI 429 GG F + E Y+I G I +P+R ++ G E ++KI VG D A Sbjct: 407 AKTMGGGSVNPATGEFNFAVSEAYLIEKGRITKPVRGATLIGKGHEIIQKIDMVGNDLAR 466 Query: 430 ETGFCG 435 + G CG Sbjct: 467 DQGMCG 472 >pir||G82325 tldD protein VC0422 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9654844|gb|AAF93595.1| (AE004129) tldD protein [Vibrio cholerae] Length = 481 Score = 151 bits (377), Expect = 2e-35 Identities = 119/444 (26%), Positives = 212/444 (46%), Gaps = 16/444 (3%) Query: 21 EYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAIKE 80 +Y ++ ++ +L L+D + + ++ GV +R ++ GF+ SD +LE + Sbjct: 34 DYADIYFQSSWHESLVLEDSIIKDGSFNIDCGVGVRAVSGEKTGFAY-SDQIQLEGLKQS 92 Query: 81 AYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLTELEKLLKEDET 140 A A + + ++ + F + ++ E ++K + L +L+ ++ E Sbjct: 93 AIAARGIAQQGQNLTVQAFKRAQHPAFYGAHNPLESWEK--QQKTELLKQLDAYIRTKEP 150 Query: 141 -VKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGAVDYG 199 + V++ Q ++ +GT + S+ V +K G + G +G Sbjct: 151 LITEVSVSLSGVHEQILVAATDGTYAGDIRPLVRLSISVLAQK-GDRRERGSAGGGGRFG 209 Query: 200 WELMTEKEPNEKVK----DRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLA 255 ++ ++E +K+ D +R+ L VA G PVV G G++ HEA+GH Sbjct: 210 YDYFLQEEAGQKIAFSFADEAIRQALVNLEAVAAPAGTMPVVLGSGWPGVLLHEAVGHGL 269 Query: 256 EADLTM--NSPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPVKDIHIIENGIL 312 E D +S F +GK++ + T+ + ++ G+ DDEGV + +IE GIL Sbjct: 270 EGDFNRKGSSVFAGKVGKKVTSDLCTIVDDGTLKDLRGSLNVDDEGVSGQYNVLIEKGIL 329 Query: 313 KEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLV 372 K + ++ A + P G+ R + Y + P+ RM NT PG+ + EE+I +K G Y Sbjct: 330 KGYIQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLPGEHTPEEIIASVKKGIYAP 389 Query: 373 DFRGGQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAIE- 430 +F GGQ + S F E Y+I NG+I PI+ ++ G IEA++++S VG D A++ Sbjct: 390 NFGGGQVDITSGKFVFSASEAYLIENGKITRPIKGATLIGSGIEAMQQVSMVGNDLALDR 449 Query: 431 -TGFCGK-GQIAFVSSGGPHMRFD 452 G CGK GQ V G P ++ D Sbjct: 450 GVGVCGKAGQSVPVGVGQPTLKLD 473 >sp|P74002|YD22_SYNY3 HYPOTHETICAL 53.1 KD PROTEIN SLR1322 >gi|7429840|pir||S75512 hypothetical protein slr1322 - Synechocystis sp. (strain PCC 6803) >gi|1653157|dbj|BAA18073.1| (D90911) hypothetical protein [Synechocystis sp.] Length = 489 Score = 148 bits (371), Expect = 9e-35 Identities = 111/448 (24%), Positives = 196/448 (42%), Gaps = 21/448 (4%) Query: 20 AEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLS--KLEEA 77 A+++E E + + +D TS T +L+ G +RV + ST+D+S L A Sbjct: 43 ADFVEFFLEKVNYVSCLAEDDAITSLTPRLSSGCGVRVYKGKGDCYVSTNDISFNGLRTA 102 Query: 78 IKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVK--PREVDIEEKVKHLTEL-EKL 134 +++ + + + ++ + D+ +K K + R ++E L +KL Sbjct: 103 LEKGLSILGLTLPAGQSFVPELNLEMLRDYAGAKEKDQWLHRCSPMQEMSDILLGANQKL 162 Query: 135 LKEDETVKSVNIRYEDGGGQKILLTNEGT---RIEWDYNYLWQSVYVTGKKEGKLAMARD 191 +S Y + ++ ++GT I + + G+ + Sbjct: 163 DHYASHAQSRRAAYFRDWQEVLVAASDGTFARDIRLTQSVGFSLFCADGEHRTSIGKRSG 222 Query: 192 SIGAVDY--GWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHE 249 DY W+ T + + ++L + + G +P++ G+I HE Sbjct: 223 DTSNPDYLRTWDAETSAQEVAESAGKMLYADYVE-------SGNYPIIMANQFGGVIFHE 275 Query: 250 ALGHLAEADLTMN--SPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPVKDIHI 306 A GHL E + +PF D G++IA E +T E + FG DDEG+P + + Sbjct: 276 ACGHLLETTQIEHKTTPFLDKKGEKIAHENLTAWDEGLTDNAFGTIDMDDEGMPTQRTLL 335 Query: 307 IENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIK 366 IENGILK + +R + + G R Q Y Y RMRNT PG++S +++ ++ Sbjct: 336 IENGILKNFIADRTGSIRTGHPRTGSGRRQSYAYAAASRMRNTYIAPGNYSVDDIFNSVE 395 Query: 367 FGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKD 426 G Y GG F + E Y++ NG++ +P++ ++ G A E + KIS +D Sbjct: 396 KGIYCKQMGGGSVGATGEFNFAVSEAYLVENGKLTKPLKGATLIGTATEIMNKISMSSQD 455 Query: 427 FAIETGFCGK-GQIAFVSSGGPHMRFDG 453 + GFCG +V+ G PH++ DG Sbjct: 456 LGLAAGFCGSVSGSVYVTVGQPHIKVDG 483 >emb|CAC11942.1| (AL445065) conserved hypothetical protein [Thermoplasma acidophilum] Length = 455 Score = 145 bits (363), Expect = 8e-34 Identities = 125/470 (26%), Positives = 210/470 (44%), Gaps = 49/470 (10%) Query: 7 LEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANG-AWGF 65 L++ L +A K+ + + R+ +++ +++G F + G AIRV+ + A + Sbjct: 2 LDRILDYAGS--KSAFADARFMEIEGRGAVIRNGEFDESLYSNDSGYAIRVVNDSIAMAY 59 Query: 66 SSTSDLSKLEEAIKEAYKLAKSASETK-----KEKIELAEIKPVEDFVKSKMKVKPREVD 120 + D K+ + +A ++ + + EK +EI D V+ Sbjct: 60 VDSEDWDKVRAVVDDAVLRSRRPGKNRIYRGRSEKASWSEIG--SDHVRDHS-------- 109 Query: 121 IEEKVKHLTELEKLLKE-DETVKSVNIRYE---DGGGQKILLTNEGTRIEWDYNYLWQSV 176 L ++ +LKE D + N+R D ++ +G+ +E Y+ ++ + Sbjct: 110 -------LGDMIAILKEADSVAEEANVRISALSDRFVHQVYENTDGSHVEGTYSRIFFNY 162 Query: 177 YVTGKKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPV 236 V + + + + G G++ K +E +K+ + L + + + G F V Sbjct: 163 LVGVSENDRYEQSSEEFGWTG-GYDAFDFKTISETMKNDV-SNLREIILAPSVEPGNFDV 220 Query: 237 VAGPIIVGLIAHEALGHLAEADLTMNSPF-----KDLLGK----QIAPEYVTM-SERYVE 286 + GP I G++AHE+ GH E D L GK +I E V++ + ++ Sbjct: 221 IVGPEISGIVAHESAGHPTEYDRIAGREAALAGESFLTGKTFPYRIGSEKVSVIDDPTLK 280 Query: 287 GGFGNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRM 346 G +G YDDEGV + ++ NG E ++NRE AA E NG R+ + P+ RM Sbjct: 281 GSYGYYLYDDEGVRARKRYLYRNGYTSEFLINRESAAWIGQESNGSGRSSSWDMEPLARM 340 Query: 347 RNTVFEPGDWSFEEMIEDIKFGYYLVDFRG---GQAQLNSAFQVGIQEGYVIRNGEIAEP 403 T EPGD+SFEE+ E + G Y+ F + N + VG +E Y I NG+I Sbjct: 341 STTYIEPGDYSFEELFEGVHRGIYIKSFTEWNIDDIRFNERY-VG-KEAYYIENGDIKGR 398 Query: 404 IRDTSITGVAIEALKKISAVGKDFAIETGFCGKG---QIAFVSSGGPHMR 450 +R + I+ + AVGKD G CGKG Q V GGPHMR Sbjct: 399 VRRPILETNTIKFYSAVDAVGKDLHFSAGICGKGDPEQGVEVWMGGPHMR 448 >pir||F82718 TldD protein XF1127 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9106089|gb|AAF83937.1|AE003949_1 (AE003949) TldD protein [Xylella fastidiosa] Length = 485 Score = 143 bits (357), Expect = 4e-33 Identities = 113/447 (25%), Positives = 212/447 (47%), Gaps = 20/447 (4%) Query: 21 EYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAIKE 80 ++ +L ++ +R + +++DG+ T + +GV +R ++ GF+ + D+++ +A+ E Sbjct: 37 DFGDLYFQHARRESWSIEDGIVKDGTHSIEQGVGVRAISGEKTGFAYSDDINR--DALLE 94 Query: 81 AYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPR-----EVDIEEKVKHLTELEKLL 135 A A++ S + + ++ + + ++ + P +D EK+ + +++LL Sbjct: 95 AAYAARAISRSPGDGVQGTHAVLLHQ--ERELCLYPALDPVGGMDNAEKIAVMRRVDQLL 152 Query: 136 KE-DETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIG 194 + D V V + G ++ ++G + +V V + G+ G Sbjct: 153 RAADPRVTQVMVNLSGGVDVVLIARSDGVLAADVRPLVRLNVQVIVEGHGRRESGYAG-G 211 Query: 195 AVDYGW-ELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGH 253 YG+ EL + P ++ L + L + L + G PVV G G++ HEA+GH Sbjct: 212 GGRYGYAELFADGRPEAFAREALRQALVN-LEAIPAPAGVMPVVLGAGWPGVLLHEAVGH 270 Query: 254 LAEADLTMN--SPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPVKDIHIIENG 310 E D S + +G+++A VT+ + ++G G+ DDEG P + +IE+G Sbjct: 271 GLEGDFNRKGTSVYAGRIGERVASPGVTIVDDGTLDGRRGSLNIDDEGTPTQCTTLIEDG 330 Query: 311 ILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYY 370 +L M + A + G+ R + + + + RM NT G S EEMI +K G Y Sbjct: 331 VLVGYMQDTLNARLMGVASTGNGRRESFAHLTMPRMTNTYMRAGVHSREEMIRSVKKGLY 390 Query: 371 LVDFRGGQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAI 429 V+F GGQ + S + E Y+I +G + PI+ ++ G E ++++ +G D A+ Sbjct: 391 AVNFGGGQVDITSGKYVFSATEAYLIEDGRVTAPIKGATLIGNGPETMQRVRMIGDDLAL 450 Query: 430 E--TGFCGK-GQIAFVSSGGPHMRFDG 453 + G CGK GQ V G P + DG Sbjct: 451 DAGVGVCGKDGQSVPVGVGQPSLLIDG 477 >sp|P45297|TLDD_HAEIN TLDD PROTEIN HOMOLOG Length = 482 Score = 141 bits (353), Expect = 1e-32 Identities = 119/456 (26%), Positives = 210/456 (45%), Gaps = 38/456 (8%) Query: 21 EYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFS-----STSDLSKLE 75 +Y +L ++ + + L+DG+ + ++RGV +R ++ GF+ + + L + Sbjct: 33 DYADLYFQLSQDESWVLEDGIIKEGSFHIDRGVGVRAVSGEKTGFAYADQINLASLQQCA 92 Query: 76 EAIK------EAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLT 129 EA+K + ++ SA A I P+E K E+K++ L Sbjct: 93 EAVKGIAQVKQGNLISPSAFNVVNPIARYAAINPLESLTK------------EKKIELLH 140 Query: 130 ELEKLLK-EDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAM 188 +++ + ED V V+ + +++ +GT + S+ V ++ GK Sbjct: 141 LVDRTARAEDHRVTKVSASLSSVYEEVLIMATDGTLAADIRPLVRLSISVLVEENGK--R 198 Query: 189 ARDSIGA-----VDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIV 243 R S G+ +D+ +E++ +R+ L+ VA G PVV G Sbjct: 199 ERGSCGSGGRFGLDWFFEVVDGDIRAVLFAKEAVRQALVNLSAVAAPAGLMPVVLGAGWP 258 Query: 244 GLIAHEALGHLAEADLTM--NSPFKDLLGKQI-APEYVTMSERYVEGGFGNDKYDDEGVP 300 G++ HEA+GH E D +S F +G+Q+ +P + + +E G+ DDEGVP Sbjct: 259 GVLLHEAVGHGLEGDFNRKESSLFTGKIGEQVTSPLCTIVDDGTIENRRGSLTIDDEGVP 318 Query: 301 VKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEE 360 + +I++GIL+ M ++ A + G+ R + Y + P+ RM NT G F++ Sbjct: 319 SQCNVLIKDGILQGYMQDKMNARLMGVSTTGNGRRESYAHLPMPRMTNTYMLAGQSQFDD 378 Query: 361 MIEDIKFGYYLVDFRGGQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKK 419 +I +K G Y F GGQ + S F E Y+I G+I +P++ ++ G IE ++K Sbjct: 379 LIASVKQGIYAPHFGGGQVDITSGKFVFSTSEAYLIEKGKITKPVKGATLIGSGIEVMQK 438 Query: 420 ISAVG--KDFAIETGFCGK-GQIAFVSSGGPHMRFD 452 IS V + + G CGK GQ V G P ++ D Sbjct: 439 ISMVADKSELDLGIGVCGKEGQSVPVGVGQPALKID 474 >pir||D83086 conserved hypothetical protein PA4474 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9950711|gb|AAG07862.1|AE004861_3 (AE004861) conserved hypothetical protein [Pseudomonas aeruginosa] Length = 480 Score = 139 bits (346), Expect = 8e-32 Identities = 112/441 (25%), Positives = 205/441 (46%), Gaps = 20/441 (4%) Query: 24 ELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAIKEAYK 83 +L ++ + L+DG+ + L++GV +R + GF+ ++ ++ EA+K+A Sbjct: 39 DLYFQSQVSESWMLEDGIVKEGSFNLDQGVGVRAQSGEKTGFAYSNAITA--EALKQAAV 96 Query: 84 LAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDI---EEKVKHLTELEKLLKE-DE 139 A+S S + ++ + V +++ +D+ EKV+ L +++ + D Sbjct: 97 AARSISRAGQN----GSVQAFKAVVPARLYAGENPLDVLSRAEKVELLKQIDAATRALDP 152 Query: 140 TVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMA-RDSIGAVDY 198 ++ V + Q ++ ++G+ + +V V ++ G+ G DY Sbjct: 153 RIQQVTVSMAGVWEQILVAASDGSLAADIRPLVRFNVSVIVEQNGRRERGGHGGGGRTDY 212 Query: 199 GWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAEAD 258 + L ++ LR+ L + G PVV G G++ HEA+GH E D Sbjct: 213 RYFLQEDRAMG--YAREALRQALVNLEAIPAPAGTLPVVMGAGWSGVLLHEAVGHGLEGD 270 Query: 259 LTM--NSPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPVKDIHIIENGILKEI 315 +S + +G+++A T+ + + G G+ DDEG P +IENG+LK Sbjct: 271 FNRKGSSAYSGRVGEKVASSLCTIVDDGTLAGRRGSLSVDDEGTPSNCNVLIENGVLKGY 330 Query: 316 MLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFR 375 M ++ A + G+ R + Y + P+ RM NT G+ +E+I ++ G Y + Sbjct: 331 MQDKLNARLMGVARTGNGRRESYAHLPMPRMTNTYMLAGESDPQEIIASVEKGIYCANLG 390 Query: 376 GGQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAIETGF- 433 GGQ + S F E Y+I NG I P++ ++ G EA+ ++S VG D A+++G Sbjct: 391 GGQVDITSGKFVFSTSEAYLIENGRITTPVKGATLIGNGPEAMSRVSMVGNDLALDSGVG 450 Query: 434 -CGK-GQIAFVSSGGPHMRFD 452 CGK GQ V G P ++ D Sbjct: 451 TCGKDGQSVPVGVGQPTLKID 471 >gb|AAC43985.2| (U33883) TldD [Bradyrhizobium japonicum] Length = 479 Score = 133 bits (331), Expect = 4e-30 Identities = 117/435 (26%), Positives = 188/435 (42%), Gaps = 15/435 (3%) Query: 24 ELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAIKEAYK 83 EL E + L +G T ++G +R + + A G++ +SD+S + + Sbjct: 39 ELFLEYSQTEALMFDNGRLKQATYDTSQGFGLRAVKDDAVGYAHSSDVS-----LPALIR 93 Query: 84 LAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVD-IEEKVKHLTELEKLLKE-DETV 141 A + + + P V+ P + E KVK L E++ L++ D V Sbjct: 94 AADAVAAVRGGYSGSFSAPPPHTNVRLYGDDNPLDAPGFETKVKLLAEIDAYLRDKDPRV 153 Query: 142 KSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGAVDYGWE 201 + V++ +L +G + ++ V + + G G+ Sbjct: 154 RQVSVTLGATWQVVEILRPDGESYRDIRPLVRVNISVVAGQGDRQESGSKGYGG-RAGYA 212 Query: 202 LMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAEADLTM 261 E + D LR+ L + GE VV G G++ HEA+GH E D Sbjct: 213 EFIESKNWRDAADGALREALVNLESIPAPAGEMDVVLGAGWPGVMLHEAVGHGLEGDFNR 272 Query: 262 N--SPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPVKDIHIIENGILKEIMLN 318 S F L+G+Q+A + VT+ + + G+ DDEG P +IE+GIL M + Sbjct: 273 KRTSAFAGLMGRQVAAKGVTVVDDGTIASRRGSLSIDDEGTPTNRTVLIEDGILVGYMQD 332 Query: 319 REYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFRGGQ 378 R+ A NM+P G+ R Q Y + P+ RM NT GD E++ +K G + +F GGQ Sbjct: 333 RQNARLMNMKPTGNGRRQGYAHVPMPRMTNTYMLAGDRDPAEILASVKNGVFAANFGGGQ 392 Query: 379 AQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAIETGF--CG 435 + S + E Y I NG+I P++ + G L +I +G D A++TG CG Sbjct: 393 VDITSGKYVFQCTEAYKIENGKIGAPLKGAMLIGNGPTDLHRIRMIGNDLALDTGIGTCG 452 Query: 436 K-GQIAFVSSGGPHM 449 K GQ V G P + Sbjct: 453 KNGQGVPVGVGQPSL 467 >pir||G70473 tldD homolog - Aquifex aeolicus >gi|2984257|gb|AAC07784.1| (AE000768) TldD protein [Aquifex aeolicus] Length = 404 Score = 127 bits (317), Expect = 2e-28 Identities = 109/399 (27%), Positives = 184/399 (45%), Gaps = 24/399 (6%) Query: 21 EYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGA--WGFSSTSDLSKLEEAI 78 EY E+ YE + T + L+D T + GV +R++ NG +G+++ L+E Sbjct: 19 EYGEIFYEKSRTTRMHLEDRKIDKVTHGYDEGVGLRLIKNGKTYYGYTTNPTFENLKE-- 76 Query: 79 KEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLTEL-EKLLKE 137 LAK + + + ++ + +++ + P + ++ + + L EK Sbjct: 77 -----LAKILARGEGHGPVAIGKRYIQGY--TEVLIDPDKESLKFRAEILRRADEKARSF 129 Query: 138 DETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGAVD 197 + +K V D + +++ G E + V V L +S+G Sbjct: 130 GDKIKQVLAVLMDKTREIMVINTLGETAEDTQKRVVFFVEVVASDGETLQRGYESLGG-R 188 Query: 198 YGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAEA 257 G+E+ E P E + ++ ++ L+ G F VV G + HEA+GH EA Sbjct: 189 RGFEIFNETPP-EVIAEKAAKRALLMLSAKPAPAGTFTVVMSSQAGGTMIHEAVGHGLEA 247 Query: 258 DLTMN--SPFKDLLGKQIAPEYVTMSER----YVEGGFGNDKYDDEGVPVKDIHIIENGI 311 DL S + LG+++A E VT+ + Y G F DDEGVP + +I++G+ Sbjct: 248 DLVQQGLSVYAGKLGEKVASELVTVIDDATLPYHNGSF---TVDDEGVPAQRKVLIKDGV 304 Query: 312 LKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYL 371 L M +R A K +E G+ R Q Y + PI+RM NT + G + E++I+D K G + Sbjct: 305 LVGYMYDRLRAMKDGVESTGNGRRQSYAHIPIVRMTNTFIDKGQDNPEDIIKDTKKGVLV 364 Query: 372 VDFRGGQAQ-LNSAFQVGIQEGYVIRNGEIAEPIRDTSI 409 V GG+ + F + EGY+I NGEI PIR ++ Sbjct: 365 VKMGGGEVNTVTGDFVFEVMEGYMIENGEITYPIRGATL 403 >pir||A82033 TLDD protein homolog NMA0367 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7379119|emb|CAB83668.1| (AL162752) TLDD protein homolog [Neisseria meningitidis Z2491] Length = 480 Score = 125 bits (310), Expect = 1e-27 Identities = 113/448 (25%), Positives = 192/448 (42%), Gaps = 49/448 (10%) Query: 37 LKDGVFTSFTEKLNRGVAIRVLANG--AWGFSSTSDLSKLEEAIKEAYKLAKSASETKKE 94 L++G+ S + ++N+GV +R ++ A+ ++ + + + + + + + + + Sbjct: 52 LEEGIVKSGSFQINQGVGVRAVSGDKTAFAYADSLCIDSINRSARAVRAIGAAGGKVSAK 111 Query: 95 KIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQ 154 KPV +D KV L ++E + K + Sbjct: 112 MPSETRGKPV-----CSASDPIAGLDSAAKVALLNKVEAIAKAADP-------------- 152 Query: 155 KILLTNEGTRIEWDYNYLWQSVYVTGK-----------------KEGKLAMARDSIGAVD 197 +I+ G E+D YL + + GK K+G+ + G Sbjct: 153 RIVQVMAGLTCEYDMVYLAR---LDGKHAADIRPMVRLNVTVIAKQGERREQGSAGGGGR 209 Query: 198 YGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAEA 257 Y E + V D +++ + L GE VV G G++ HEA+GH E Sbjct: 210 YDLAYFDENLVRQFV-DAAVKQALTNLESRPAPAGEMTVVLGNGWPGVLLHEAVGHGLEG 268 Query: 258 DLTMN--SPFKDLLGKQIAPEYVTMSERY-VEGGFGNDKYDDEGVPVKDIHIIENGILKE 314 D S F +G+++A + VT+ ++ + G G+ DDEG + +IE+GIL Sbjct: 269 DFNRKGTSVFSGRIGERVAAKGVTVVDQGDIAGRRGSLNIDDEGNETRRTVLIEDGILVG 328 Query: 315 IMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDF 374 M + A + G+ R + Y P+ RM NT E G + EE+I I G Y V+F Sbjct: 329 YMQDETNARLTGTQSTGNGRRESYASAPMPRMTNTFMENGSYEPEEIIASIDKGIYAVNF 388 Query: 375 RGGQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAIET-- 431 GGQ + S F E + + G + P++ +I G E LK +S +G D A+++ Sbjct: 389 GGGQVDITSGKFVFSASEAWWVEGGRLQYPVKGATIIGNGPEVLKHVSMIGNDTALDSGV 448 Query: 432 GFCGK-GQIAFVSSGGPHMRFDGGIIIG 458 G CGK GQ V G P +R D G+ +G Sbjct: 449 GVCGKEGQSVPVGVGQPTLRIDAGLTVG 476 >pir||F81010 tldD protein NMB2066 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7227328|gb|AAF42385.1| (AE002556) tldD protein [Neisseria meningitidis MC58] Length = 480 Score = 124 bits (309), Expect = 2e-27 Identities = 82/252 (32%), Positives = 125/252 (49%), Gaps = 7/252 (2%) Query: 214 DRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAEADLTMN--SPFKDLLGK 271 D +++ + L GE VV G G++ HEA+GH E D S F +G+ Sbjct: 225 DAAVKQALTNLESRPAPAGEMTVVLGNGWPGVLLHEAVGHGLEGDFNRKGTSVFSGRIGE 284 Query: 272 QIAPEYVTMSERY-VEGGFGNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPN 330 ++A + VT+ ++ + G G+ DDEG + +IE+GIL M + A + Sbjct: 285 RVAAKGVTVVDQGDIAGRRGSLNIDDEGNETRRTVLIEDGILVGYMQDETNARLTGTQST 344 Query: 331 GHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFRGGQAQLNSA-FQVGI 389 G+ R + Y P+ RM NT E G + EE+I I G Y V+F GGQ + S F Sbjct: 345 GNGRRESYASAPMPRMTNTFMENGSYEPEEIIASIDKGIYAVNFGGGQVDITSGKFVFSA 404 Query: 390 QEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAIET--GFCGK-GQIAFVSSGG 446 E + + G + P++ +I G E LK +S +G D A+++ G CGK GQ V G Sbjct: 405 SEAWWVEGGRLQYPVKGATIIGNGPEVLKHVSMIGNDTALDSGVGVCGKEGQSVPVGVGQ 464 Query: 447 PHMRFDGGIIIG 458 P +R D G+ +G Sbjct: 465 PTLRIDAGLTVG 476 >pir||E72342 pmbA-related protein - Thermotoga maritima (strain MSB8) >gi|4981252|gb|AAD35809.1|AE001743_11 (AE001743) pmbA-related protein [Thermotoga maritima] Length = 435 Score = 117 bits (291), Expect = 2e-25 Identities = 109/418 (26%), Positives = 191/418 (45%), Gaps = 33/418 (7%) Query: 23 IELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAIKEAY 82 +++ + + + +L L +G +T+ V I+VL +G G T L E+ +EA Sbjct: 21 VQISFLETREFSLRLANGDLDQYTDAGKFNVEIKVLKDGKTGTFRTQVLENPEKCFEEAL 80 Query: 83 K-LAKSASETKKEKIELA-EIKPVEDFVKSKMKVKPREVDIEEKVKHLTELEKLLKEDET 140 L SE K+ E E + +E +V K+ +E K H E K++ Sbjct: 81 SNLQVKDSEEKEYFFEGGKEYREMETYVGRFEKLSVKEKMDMAKKAH----ESAAKDERV 136 Query: 141 VKSVNIRYEDGGGQKILLTNEGTRIE--WDYNYLWQSVYVTGKKEGKLAMARDSIGAVDY 198 V + Y+D +KI+ G +E D +L+ +A+ARD+ Sbjct: 137 VMVPTVMYKDMVIKKIITNTLGLDVESQMDGGFLFA-----------MAIARDANPRSGS 185 Query: 199 GWELMTEKEP--NEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAE 256 +EL E E++ R + S + G++PV+ + + + ++ Sbjct: 186 WYELARTPEDLNPEEIGKRAAEEAISLIGSKTIPSGKYPVLMRNTALLDLMEMFIPMISA 245 Query: 257 ADLTMN-SPFKDLLGKQIAPEYVTMSER-YVEGGFGNDKYDDEGVPVKDIHIIENGILKE 314 ++ N SP K LG+Q+ V++ + Y G + +DDEGVP + ++ENG+LK Sbjct: 246 ENVQKNLSPLKGKLGEQVGNPAVSIKDLPYHPKGLSSTPFDDEGVPTTEKFVLENGVLKT 305 Query: 315 IMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDF 374 + N + A K +EP G+ + IR N + PG+ SFEE+++++ G + + Sbjct: 306 FLHNLKTARKEGVEPTGNG------FVGGIRPVNLMLMPGEKSFEELLKEMDRGVVITEV 359 Query: 375 RGGQAQLNS---AFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAI 429 G A NS F + +GY + NGEIA + D +I+G ++ L+KI VG D + Sbjct: 360 EGMHAGANSISGEFSL-FAKGYWVENGEIAHGVEDITISGNFLDLLRKIVLVGNDVKV 416 >dbj|BAB05755.1| (AP001514) suppressor of the inhibitory activity of the cabon storage regulator (CsrA) [Bacillus halodurans] Length = 432 Score = 112 bits (278), Expect = 7e-24 Identities = 76/228 (33%), Positives = 113/228 (49%), Gaps = 13/228 (5%) Query: 232 GEFPVVAGPIIVGLIAHEALGHLAEADLTM--NSPFKDLLGKQIAPEYVTMSERYVEGGF 289 G + ++ GP+ I HE +GH EAD+ S F LG + E VT+ + + G Sbjct: 198 GSYALILGPLAAPGIFHEVVGHGLEADIASIPQSAFHQRLGAMVGCEKVTIIDDPTKEGL 257 Query: 290 -GNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRN 348 G+ DDEG + +IE G + + + NGH R +Y++ P++RM N Sbjct: 258 PGSYSLDDEGTIAQQTTLIEKGRVVNYLSHLHTGHP----TNGHGRVINYQHLPLVRMSN 313 Query: 349 TVFEPGDWSFEEMIEDIKFGYYLVDFRGGQAQL-NSAFQVGIQEGYVIRNGEIAEPIRDT 407 T PG EEM+ D + G Y+ G + F++ + EGY+I G+I PI T Sbjct: 314 TFLLPGTDDPEEMVSDTEVGLYVKKAINGDVNMITGEFEIHVAEGYLIEKGQITSPILPT 373 Query: 408 SITGVAIEALKKISAVGKDFAIET---GFCGK-GQIAF-VSSGGPHMR 450 ++ G + L+ I VG DFAI + G CGK GQ VS+G P +R Sbjct: 374 TLKGDGQKLLQSIDRVGNDFAIHSEVRGGCGKLGQSPLPVSAGSPTVR 421 >pir||S70839 tldD homolog - Bradyrhizobium japonicum (fragment) Length = 313 Score = 107 bits (265), Expect = 2e-22 Identities = 80/241 (33%), Positives = 114/241 (47%), Gaps = 8/241 (3%) Query: 217 LRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAEADLTMN--SPFKDLLGKQIA 274 LR+ L + GE VV G G++ HEA+GH E D S F L+G+Q+A Sbjct: 61 LREALVNLESIPAPAGEMDVVLGAGWPGVMLHEAVGHGLEGDFNRKRTSAFSGLMGRQVA 120 Query: 275 PEYVTM-SERYVEGGFGNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHA 333 + VT+ + + G+ DDEG P +IE+GIL M +R+ A NM+P G+A Sbjct: 121 AKGVTVVDDGTIASRRGSLSIDDEGTPTNRTVLIEDGILVGYMQDRQNARLMNMKPTGNA 180 Query: 334 RAQDYRYPPIIRMRNTVFEPG-DWSFEEMIEDIKFGYYLVDFRGGQAQLNSAFQVG-IQE 391 A+ Y + P+ RM NT G S ++ +K +F GGQ + S V E Sbjct: 181 AARRYAHVPMPRMTNTYMLRGRSRSGRGVLASVKNAASRANFGGGQVDITSGKYVSQCTE 240 Query: 392 GYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAIETGF--CGK-GQIAFVSSGGPH 448 Y NG+ P + G L +I +G D A++TG CGK GQ V G P Sbjct: 241 AYKSENGKSGGPAEGRMLIGNGPTDLHRIRMIGNDLALDTGIGTCGKNGQGVPVGVGQPS 300 Query: 449 M 449 + Sbjct: 301 L 301 >pir||D70703 tldD homolog Rv2315c - Mycobacterium tuberculosis (strain H37RV) >gi|1524285|emb|CAB02052.1| (Z79702) hypothetical protein Rv2315c [Mycobacterium tuberculosis] Length = 505 Score = 98.7 bits (242), Expect = 1e-19 Identities = 115/479 (24%), Positives = 187/479 (39%), Gaps = 32/479 (6%) Query: 5 ESLEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWG 64 + L A A A + +LR + + L+DG + G+A+RV+ G WG Sbjct: 17 QQLADAALSAAATAGASHADLRVHRISTEIIQLRDGELETAVISRELGLAVRVIVAGTWG 76 Query: 65 FSSTSDLSK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVK--SKMKVKPREVD 120 F+S ++L+ + A +A + E++ LA +PV + S ++ P V Sbjct: 77 FASHAELAPDVAAATARHAVHVATVLAALNTERVRLAP-EPVYTDAEWVSNYRIDPFGVP 135 Query: 121 IEEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQ--SVYV 178 EK+ L + L + + + V+ Q G+ I L Sbjct: 136 ASEKIAVLRDYSGRLLDADGIDHVSASLNAVKEQTFYADTFGSSITQQRVRLLPCLDAVA 195 Query: 179 TGKKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKD--RLLRKLHSQLNGVAPKRGEFPV 236 G R GWE++ E + +L L ++ + G + Sbjct: 196 VDSAAGNFESMRTLAPPTARGWEVVAGDEIWNWTDELAQLPSLLAEKVRAPSVMPGPTDL 255 Query: 237 VAGPIIVGLIAHEALGHLAEADLTM---------NSPFKDLLG--KQIAPEYVTMSERYV 285 V P + L HE++GH E D + + D LG + +P ++R Sbjct: 256 VIDPTNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGTLRYGSPVMNVTADRTA 315 Query: 286 EGGFGNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEP--NGHARAQDYRYPPI 343 E G YDDEGV + ++ +G+ L+R +A + EP NG + A + PI Sbjct: 316 EFGLATVGYDDEGVAAQSWDLVRDGVFVGYQLDRAFAPRLG-EPRSNGCSYADSPHHVPI 374 Query: 344 IRMRNTVFEPG--DWSFEEMIEDIKFGYYLVDFRGGQAQLNS-AFQVGIQEGYVIRNGEI 400 RM N +PG D S ++I + G Y+V + + FQ Q + IR G++ Sbjct: 375 QRMANISLQPGIEDLSTADLIGRVDDGIYIVGDKSWSIDMQRYNFQFTGQRFFRIRGGQL 434 Query: 401 AEPIRDTSITGVAIEALKKISAVGKDFAIETG---FCGK---GQIAFVSSGGPHMRFDG 453 +RD + + + AVG G CGK GQ+A VS G P F G Sbjct: 435 YGQLRDVAYQSSTTDFWNAMEAVGGPSTWRMGGAINCGKAQPGQVAAVSHGCPSALFRG 493 >gb|AAD53904.1|AF176314_14 (AF176314) PmbA [Zymomonas mobilis] Length = 448 Score = 91.3 bits (223), Expect = 2e-17 Identities = 95/358 (26%), Positives = 163/358 (44%), Gaps = 28/358 (7%) Query: 67 STSDLSK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEK 124 S+SD SK L+ ++ A +A+ A E + A + P E ++ E D ++ Sbjct: 70 SSSDFSKEALDALVERAVAMAREAPEDR-----WAGLAPKELLMQGT--APEIESDDGKE 122 Query: 125 VKHLTELEKLLKEDETVKSVN-IRYEDGG----GQKI--LLTNEG-TRIEWDYNYLWQSV 176 + E LK ++ +SV+ I +G G+ I L T+EG TR +Y + Sbjct: 123 IAPAVLRELALKAEDAARSVDGITNSEGASASAGRTIFALATSEGFTRGSSSSSYGCSAC 182 Query: 177 YVTGKKEGKLAMARD-SIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFP 235 + G+ + M RD A Y +L + E + R + ++LN G+ P Sbjct: 183 VIAGQG---VNMQRDYDFHATRYFEDL----DAAELIGTRAAERTIARLNPTRIDSGQMP 235 Query: 236 VVAGPII-VGLIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSER-YVEGGFGNDK 293 ++ P + G +++ G A S D LGK + E +T+ E + + G + Sbjct: 236 IIFDPRVGSGFLSYLIQGISGGAITRKTSFLLDSLGKPVFNEGITIKEDPWRKRGIASRA 295 Query: 294 YDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEP 353 +D EG+P K +II+ G L +L+ A + M P GHAR + PP N E Sbjct: 296 FDGEGLPTKPNNIIDKGRLNGWLLDSAAARQLGMTPTGHAR-RGVGGPPSTGTANLYLEA 354 Query: 354 GDWSFEEMIEDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITG 411 G + EE++ DIK G Y+ + G + + G++IR+G++AEP+ + ++ G Sbjct: 355 GKVTPEELMSDIKLGIYVTEMIGSGVNMITGDYSRGASGFIIRDGQLAEPVAEITVAG 412 >pir||F71033 hypothetical protein PH1558 - Pyrococcus horikoshii >gi|3257987|dbj|BAA30670.1| (AP000006) 445aa long hypothetical protein [Pyrococcus horikoshii] Length = 445 Score = 90.9 bits (222), Expect = 3e-17 Identities = 104/432 (24%), Positives = 188/432 (43%), Gaps = 22/432 (5%) Query: 4 MESLEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAW 63 M +E+ +K+ E + +E+ + L ++ + T +++ +R + + Sbjct: 1 MRKMEELIKYGERFF--DELEIVTYRAREIGLEVELNEISMGTTRMSTITIVRGIKDNRI 58 Query: 64 GFSSTSDLSK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDI 121 G S + SK +++AI+EA K+A+ + K K L E P + K K+ + +E Sbjct: 59 GISIVDNDSKEDVKKAIEEAAKMARLNNPDDKWK-SLPE--PGKYREKPKVNEELKEAST 115 Query: 122 EEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQKILLTNE-GTRIEWDYNYLWQSVYVTG 180 E + + +L +E + +V + + N G + +Y + G Sbjct: 116 ETLASMVIKGIQLARESDPNVTVAGGSAGASWSEFSIANSHGVNVTQEYGHAHVFFEFVG 175 Query: 181 KKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGP 240 KKEG + I D L + E + +R + ++ K E PV+ P Sbjct: 176 KKEG---VVTPGIFEFDIKDNLNLDVE---SIVNRGIERVKWAYKVKEAKNEEAPVIFSP 229 Query: 241 IIVGLIAHEAL--GHLAEADLTMNSPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDE 297 + + H AL E + +P D +G++IA + +T+ + + E D E Sbjct: 230 WAISGLFHYALFPAFSGERLIKKTTPLADKVGEKIASDVITIYDDTFHELSVVKAIADGE 289 Query: 298 GVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPI-IRMRNTVFEPGDW 356 GVP + +IENG+ K + + +A + E GH + +D+R + I + + V E G Sbjct: 290 GVPTRKTMLIENGVFKGFIWDNYWAKVYGTESTGHGQ-RDWRGGGVTIGLNSAVIENGKR 348 Query: 357 SFEEMIEDIKFGYYLVDFRGGQAQL--NSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAI 414 S EEMI+DIK GY + +G + N F + Y+I +GEIA + + Sbjct: 349 SLEEMIQDIKHGYLVEGVQGAHSSNPDNGNFAISANPAYLIEDGEIAGSTVFLVASNI-Y 407 Query: 415 EALKKISAVGKD 426 E LK+ S V K+ Sbjct: 408 ELLKQASEVSKE 419 >pir||D82066 pmbA protein VC2535 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9657118|gb|AAF95676.1| (AE004322) pmbA protein [Vibrio cholerae] Length = 447 Score = 88.9 bits (217), Expect = 1e-16 Identities = 65/213 (30%), Positives = 106/213 (49%), Gaps = 16/213 (7%) Query: 222 SQLNGVAPKRGEFPVV-AGPIIVGLIAHEALGHLAEADLTMNSPFK-DLLGKQIAPEYVT 279 S+L+ K G+FPV+ A + GLI H + ++ +L S F D LGK I P + Sbjct: 229 SRLDPQKLKTGQFPVMFAADVATGLIGHLVMA-ISGGNLYRKSSFLLDHLGKTILPTWFN 287 Query: 280 MSER-YVEGGFGNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDY 338 +SER +V G + +D EGV +D+ II +G+L +L A K NM P GHA Sbjct: 288 ISERPHVMRGLASSPFDSEGVRTQDLEIITDGVLATYLLTSYAARKMNMTPTGHAGG--- 344 Query: 339 RYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNG 398 + N + ++++M++++ G + + G + + G+ + NG Sbjct: 345 -------IHNWYVKSTGQNYQQMLKELGTGLLVTEVMGQGVNVVTGDYSRGAAGFWVENG 397 Query: 399 EIAEPIRDTSITGVAIEALKKISAVGKDFAIET 431 EI P+ + +I G + L++I AVG D IET Sbjct: 398 EIKYPVSEITIAGNLKQMLQQIVAVGSD--IET 428 >pir||B75213 pmba protein (tlde protein) PAB0155 - Pyrococcus abyssi (strain Orsay) >gi|5457662|emb|CAB49153.1| (AJ248283) PMBA PROTEIN (TLDE PROTEIN) [Pyrococcus abyssi] Length = 427 Score = 86.6 bits (211), Expect = 5e-16 Identities = 98/396 (24%), Positives = 169/396 (41%), Gaps = 39/396 (9%) Query: 48 KLNRGVAIRVLANGAWGFSSTSDLS----KLEEAIKEAYKLAKSASETKKEKIELAEIKP 103 +++ G+ +RVL G GFS S + +LE +K AYK+AK A + Sbjct: 49 EVSGGIGLRVLTQGKIGFSYISGSNFTREQLERLVKRAYKIAKVAGSIYPGFPVPKKFPN 108 Query: 104 VEDFVKSKMKVKPREVDIEEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQKILLTNEGT 163 V K+ R + EE V++ TEL + E S+ + + G ++ + GT Sbjct: 109 VRGLYDDKI----RNLSTEEIVEYGTELVDVPPNAEA--SIGLSTSERG----IMNSNGT 158 Query: 164 RIEWDYNYLWQSVYVTGKKEGKLAMARDSIGAVDYGWELMTEKEPN-EKVKDRLLRKLHS 222 + L +YV K +G G+ + + + E E V+++ L + Sbjct: 159 EGREERTLLAFGLYVFEKSKGT--------GSYSKSFRRLPKLESEIEGVREKALWEFEM 210 Query: 223 QLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTM-S 281 ++ ++ P V I L +++ ++ + LG ++A +T+ Sbjct: 211 SSKARKLEKYNGEIILEPKAVASILSIFLPNVSARNVYLKRSRFTELGIEVASGGLTIID 270 Query: 282 ERYVEGGFGNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYP 341 + VEGG + +D EG P II+ GIL + +++Y + G+A ++ Y Sbjct: 271 DPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNA-SRGYSSQ 329 Query: 342 PIIRMRNTVFEPGDWSFEEMIEDIKF-GYYLVDFRGGQAQLNSA---FQVGIQEGYVIRN 397 P I N + PG+ +E E I G Y G+ NS F + + GYV+R Sbjct: 330 PSISPSNIMISPGN---DEQDEGIFIRGIY------GEHTANSVSGDFSLNVDLGYVVRG 380 Query: 398 GEIAEPIRDTSITGVAIEALKKISAVGKDFAIETGF 433 GEI P + + G E LK ++ +GK+ I GF Sbjct: 381 GEI-RPFKGNMLVGNVFEMLKNVTNIGKEIEILDGF 415 >pir||B75180 antibiotic/peptide maturation related protein PAB1956 - Pyrococcus abyssi (strain Orsay) >gi|5458031|emb|CAB49521.1| (AJ248284) ANTIBIOTIC/PEPTIDE MATURATION related protein [Pyrococcus abyssi] Length = 448 Score = 83.9 bits (204), Expect = 3e-15 Identities = 93/368 (25%), Positives = 163/368 (44%), Gaps = 22/368 (5%) Query: 68 TSDLSKLEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKH 127 T ++++AI+EA K+AK + +K + K E K K+ + V E V+ Sbjct: 68 TDSKEEVKKAIEEAAKMAKLNTPDEKWSSLPSPGKYRE---KPKVSEDLKSVSTETLVEF 124 Query: 128 LTELEKLLKEDETVKSVNIRYEDGG---GQKILLTNEGTRIEWDYNYLWQSVYVTGKKEG 184 +T KL +E + +V + G + + ++G + ++ GKKEG Sbjct: 125 VTRGIKLARESDP--NVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKKEG 182 Query: 185 KLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGP-IIV 243 + G D+ + E + E V +R L ++ N K E V+ GP I Sbjct: 183 VVTP-----GIFDFDAKDNLELDV-EGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAIS 236 Query: 244 GLIAHEALGHLA-EADLTMNSPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPV 301 GL+++ + E + +P D +G+++A + +T+ + + E D EGVP Sbjct: 237 GLLSYALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPT 296 Query: 302 KDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPI-IRMRNTVFEPGDWSFEE 360 + + +IE GI K + + +A + E GH + +D+R + I + + V E G E Sbjct: 297 RKVTLIEEGIFKGFIWDNYWAKVYGTESTGHGQ-RDWRGGGVSIGLNSAVIENGKRELSE 355 Query: 361 MIEDIKFGYYLVDFRGGQAQL--NSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALK 418 +I +IK GY + +G + N F V Y+I +GE+ I G E LK Sbjct: 356 IIGEIKHGYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVVGS-TVFLIAGNVYELLK 414 Query: 419 KISAVGKD 426 + + V KD Sbjct: 415 QATEVSKD 422 >pir||B83330 hypothetical protein PA2529 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9948585|gb|AAG05917.1|AE004680_5 (AE004680) hypothetical protein [Pseudomonas aeruginosa] Length = 477 Score = 83.1 bits (202), Expect = 6e-15 Identities = 99/453 (21%), Positives = 187/453 (40%), Gaps = 35/453 (7%) Query: 12 KWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDL 71 ++A +AE+ LRY L+++ V +RG + V NG +++T+DL Sbjct: 8 RFAALRSRAEFHSLRYVQRSGEYLSVRRNVSEPPHFSQDRGAMLCVRLNGVEAYAATNDL 67 Query: 72 SK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLT 129 S L+ A+++A E + E+I + V + + + R + + L Sbjct: 68 SAAGLQAALEQA--------ERQAERIARHALFDVRGLPPASGRSQYRSPNQDAPFPSLA 119 Query: 130 ELEKLLKE-------DETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKK 182 E +LL E DE + + ++ E +++ L + G + +++ VT Sbjct: 120 ECYELLAEESAKVPRDERLVNWSVFLEVSRQEQLYLNSAGAEQYHEQRFVYPGASVTAY- 178 Query: 183 EGKLAMARDSIG--AVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGP 240 +G + R G A G + E+ R+ + L G ++ P Sbjct: 179 DGHDSQTRSFGGHHAGQQGGAEVIERLGLVGAAPRIADQALQLLAAPNTPSGRCDLLLMP 238 Query: 241 IIVGLIAHEALGHLAEADLTMNSP----------FKDLLGKQIAPEYVTMS-ERYVEGGF 289 + L HE++GH E D + +D Q + +S + + Sbjct: 239 DQMILQIHESIGHPLELDRILGDERNYAGTSFIKTEDFGRYQYGSSLLNVSFDPEIPEEL 298 Query: 290 GNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNT 349 + + DD+G P + ++I G L + + +E ++RA + PI RM N Sbjct: 299 ASYRQDDDGSPARKEYLIREGRLLRPLGGALSQHRSGLEGVANSRASSWNRAPIDRMANL 358 Query: 350 VFEPGDWSFEEMIEDIKFGYYLVDFRGGQAQ-LNSAFQVGIQEGYVIRNGEIAEPIRDTS 408 EPGD SF +++ I+ G + R + FQ G + G +I +GE+ +++ + Sbjct: 359 NLEPGDKSFAQLVAGIERGVLMSYNRSWSIDDARNKFQFGCEWGQLIEDGELKGVVKNPN 418 Query: 409 ITGVAIEALKKISAVGKDFAIE---TGFCGKGQ 438 G++ + + +SAVG E T +CGKG+ Sbjct: 419 YRGISAQFWRNLSAVGDAGTFEVLGTPYCGKGE 451 >pir||T36780 hypothetical protein SCI28.10 - Streptomyces coelicolor (fragment) >gi|5525068|emb|CAB50884.1| (AL096844) hypothetical protein [Streptomyces coelicolor A3(2)] Length = 435 Score = 82.7 bits (201), Expect = 8e-15 Identities = 101/406 (24%), Positives = 165/406 (39%), Gaps = 28/406 (6%) Query: 20 AEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAIK 79 AE+ + R E ++ + L+D ++ + G A+RV+ G WGF+S DL+ L+ A K Sbjct: 30 AEHADFRLERVRNASWRLRDARPAGSSDTTDLGYAVRVVHGGTWGFASGVDLT-LDAAAK 88 Query: 80 ---EAYKLAKSASETKK-----EKIEL-AEIKPVEDFVKSKMKVKPREVDIEEKVKHLTE 130 +A +AK +++ K E++EL AE + S ++ P V +K L + Sbjct: 89 VASQAVAMAKLSAQVIKAAGSDERVELAAEPVHADKSWISAYEIDPFSVPDADKAALLAD 148 Query: 131 LEKLLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQ--SVYVTGKKEGKLAM 188 L + V V+ K GT L + G+ Sbjct: 149 WSARLLAADGVDHVDASLLTVHENKFYADTAGTVTTQQRVRLHPVLTAVSVDDSSGEFDS 208 Query: 189 ARDSIGAVDYGWELMTEKEPN-EKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIA 247 R GWE +T + + + L ++ + + G + +V P + L Sbjct: 209 MRTLAPPAGRGWEYLTGTGWDWDSELAEIPELLAEKMRAPSVEAGLYDLVVDPSNLWLTI 268 Query: 248 HEALGHLAEADLTMNSPFK---------DLLGK-QIAPEYVTMS-ERYVEGGFGNDKYDD 296 HE++GH E D + D LGK + E + ++ +R E G YDD Sbjct: 269 HESIGHATELDRALGYEAAYAGTSFATFDQLGKLRYGSELMNVTGDRTAEHGLATVGYDD 328 Query: 297 EGVPVKDIHIIENGILKEIMLNREYAAKFNME-PNGHARAQDYRYPPIIRMRNTVF--EP 353 EGV + ++++G L L+R A E NG A A + P+ RM N +P Sbjct: 329 EGVEGQSWDLVKDGTLVGYQLDRRIARLTGFERSNGCAYADSPAHVPVQRMANVSLLPDP 388 Query: 354 GDWSFEEMIEDIKFGYYLVDFRGGQAQLNS-AFQVGIQEGYVIRNG 398 G S E++I + G Y+V R + FQ Q + I NG Sbjct: 389 GGLSTEDLIGGVDRGIYVVGDRSWSIDMQRYNFQFTGQRFFRIENG 434 >pir||E71135 hypothetical protein PH0849 - Pyrococcus horikoshii >gi|3257260|dbj|BAA29943.1| (AP000003) 443aa long hypothetical protein [Pyrococcus horikoshii] Length = 443 Score = 80.4 bits (195), Expect = 4e-14 Identities = 58/200 (29%), Positives = 102/200 (51%), Gaps = 12/200 (6%) Query: 232 GEFPVVAGPI-IVGLIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSE-RYVEGGF 289 G F V+ P+ L+++ A A S F + L +++A E VT+ + + G+ Sbjct: 221 GRFDVIFDPLAFANLLSYMGWAFSAFAVEAGFSYFANKLDQKVASEIVTIKDVGNLPNGY 280 Query: 290 GNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNT 349 K+DDEGVP K+ +I GILK + N A K+ E +A P R N Sbjct: 281 ATRKFDDEGVPTKETILIHKGILKTYLFNTSLAKKYGRETTANAGL----IAP--RAWNI 334 Query: 350 VFEPGDWSFEEMIEDIKFGYYLVD--FRGGQAQLNSAFQVGIQEG-YVIRNGEIAEPIRD 406 V EPGD++ +E+ +++K G Y+ + + Q + F ++G ++I NGE+ +PIR+ Sbjct: 335 VLEPGDYTKDELFQEVKKGIYITNVWYTRFQNYMTGDFSTIPRDGIFLIENGEL-KPIRN 393 Query: 407 TSITGVAIEALKKISAVGKD 426 ++ + L+ + A+ K+ Sbjct: 394 IRVSDNMLRILQNVVALSKE 413 >pir||F75033 hypothetical protein PAB1548 - Pyrococcus abyssi (strain Orsay) >gi|5458676|emb|CAB50163.1| (AJ248287) hypothetical protein [Pyrococcus abyssi] Length = 443 Score = 80.0 bits (194), Expect = 5e-14 Identities = 57/200 (28%), Positives = 102/200 (50%), Gaps = 12/200 (6%) Query: 232 GEFPVVAGPI-IVGLIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSE-RYVEGGF 289 G+F V+ P+ L+++ A A S F + L +++A E VT+ + + G+ Sbjct: 221 GKFDVIFDPLAFANLLSYMGWAFSAFAVEAGFSYFANKLDQKVASEVVTIKDIGNLPNGY 280 Query: 290 GNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNT 349 G K+DDEGVP ++ +IE G LK + N A K+ E +A R N Sbjct: 281 GTRKFDDEGVPTRETVLIERGTLKTYLFNTSLAKKYGKETTANAGLIS------PRAWNI 334 Query: 350 VFEPGDWSFEEMIEDIKFGYYLVD--FRGGQAQLNSAFQVGIQEG-YVIRNGEIAEPIRD 406 V EPGD++ +E+ +++K G Y+ + + Q + F ++G ++I NGE+ +PIR+ Sbjct: 335 VLEPGDYTKDELFQEVKRGIYITNVWYTRFQNYMTGDFSTIPRDGIFLIENGEL-KPIRN 393 Query: 407 TSITGVAIEALKKISAVGKD 426 ++ + L+ I + K+ Sbjct: 394 IRVSDNMLRILQNIVGLTKE 413 >pir||S77207 hypothetical protein slr1435 - Synechocystis sp. (strain PCC 6803) >gi|1652621|dbj|BAA17541.1| (D90907) PmbA protein [Synechocystis sp.] Length = 427 Score = 79.6 bits (193), Expect = 7e-14 Identities = 56/222 (25%), Positives = 107/222 (47%), Gaps = 14/222 (6%) Query: 210 EKVKDRLLR-KLHSQLNGVAPKRGEFPVV----AGPIIVGLIAHEALGHLAEADLTMNSP 264 E ++ RLL +++ Q+ G G+ P++ A ++ + G D +SP Sbjct: 194 ENLRQRLLWVEVNQQIQG-----GKMPILLTSGAASLLWDTVGEALHGQRVAED---SSP 245 Query: 265 FKDLLGKQIAPEYVTMSERYVEGGFGNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAK 324 + + LG+ +A E + +S+ F + +DDEG + + +I+NG + + + E A K Sbjct: 246 WAEKLGQTVAIEELNISQDPTAIPF-DCPFDDEGSRTQKLALIKNGKIAQFYTDHETAEK 304 Query: 325 FNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFRGGQAQLNSA 384 G+ P + N + PG SF+++++ + G + GG A ++ Sbjct: 305 LGTTTTGNGFRPSLGSAPQPGLVNMLITPGTASFDQLLKKLGNGLVVDQILGGGADISGD 364 Query: 385 FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKD 426 F + + GY ++NGEI ++DT ++G E L +I A+G D Sbjct: 365 FSINVDLGYRVQNGEITGRVKDTMVSGNIYELLNQIIALGSD 406 >sp|P45077|PMBA_HAEIN PMBA PROTEIN HOMOLOG >gi|1075002|pir||C64186 pmbA protein - Haemophilus influenzae (strain Rd KW20) >gi|1574709|gb|AAC22807.1| (U32795) pmbA protein (pmbA) [Haemophilus influenzae Rd] Length = 451 Score = 78.8 bits (191), Expect = 1e-13 Identities = 91/383 (23%), Positives = 160/383 (41%), Gaps = 34/383 (8%) Query: 64 GFSSTSDLSKLEEAIKEAYKLAKS-ASETKKEKIELAEIKPVEDFVKSKMKV-KPREVDI 121 G +STSDLS E AIK A + A + A T + K + F +++ ++D+ Sbjct: 77 GNASTSDLS--ESAIKNAVEAALAIAKYTSPDDCTGLADKDLMAFDAPDLELYHAADIDV 134 Query: 122 EEKVKHLTELEK--LLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVT 179 ++ + + E+ L ++ + S + G K+ + G + + S V Sbjct: 135 DKATELALQAEQAALQADERIINSNGASFNSHTGVKVYGNSHGMLQSYLSSRYSLSCSVI 194 Query: 180 GKKEGKLAMARDSIGAVDYGWELMTEKEPNEK---VKDRLLRKLHSQLNGVAPKRGEFPV 236 G E L DY + + E + + V + +K+ S+LN E PV Sbjct: 195 GGVEDALEN--------DYEYTISREFDKLQSPIWVGENCAKKVVSRLNPQKLSTREVPV 246 Query: 237 V-AGPIIVGLIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSER-YVEGGFGNDKY 294 + + G+I+H A + +S D LGKQ+ P++ ++SER ++ + + Sbjct: 247 IFLNDVATGIISHFAAAISGGSLYRKSSFLLDHLGKQVLPDWFSISERPHLLRRLASTPF 306 Query: 295 DDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPG 354 D EGV +D I+ENGIL+ ++ K M GHA + N + +P Sbjct: 307 DSEGVRTQDREIVENGILQTYLVTSYSGKKLGMSSTGHAGG----------IHNWLVKPN 356 Query: 355 -DWSFEEMIEDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVA 413 ++ + G + D G + + G+ + NGEI P+ + +I G Sbjct: 357 LTGGLTALLRQMGTGLLVTDVMGQGVNIVTGDYSRGASGFWVENGEIQYPVAEITIAGQL 416 Query: 414 IEALKKISAVGKDFA----IETG 432 + LK + AV D I+TG Sbjct: 417 QDMLKNMLAVADDIEHRSNIQTG 439 >sp|P24231|PMBA_ECOLI PMBA PROTEIN (TLDE PROTEIN) >gi|96308|pir||S13730 pmbA protein - Escherichia coli >gi|42440|emb|CAA38091.1| (X54152) pmbA is involved in the production of antibiotic MccB17 [Escherichia coli] >gi|537077|gb|AAA97132.1| (U14003) pmbA gene product [Escherichia coli] >gi|1732440|dbj|BAA07915.1| (D44452) TldE protein [Escherichia coli] >gi|1790682|gb|AAC77192.1| (AE000494) maturation of antibiotic MccB17, see tld genes [Escherichia coli K12] Length = 450 Score = 74.5 bits (180), Expect = 2e-12 Identities = 66/247 (26%), Positives = 114/247 (45%), Gaps = 20/247 (8%) Query: 197 DYGWEL---MTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVV-AGPIIVGLIAHEALG 252 DY + + M++ + E V R+ S+L+ + PV+ A + GL H +G Sbjct: 204 DYAYTIGRAMSDLQTPEWVGADCARRTLSRLSPRKLSTMKAPVIFANEVATGLFGH-LVG 262 Query: 253 HLAEADLTMNSPFK-DLLGKQIAPEYVTMSER-YVEGGFGNDKYDDEGVPVKDIHIIENG 310 +A + S F D LGKQI P+++T+ E ++ G + +D EGV + II++G Sbjct: 263 AIAGGSVYRKSTFLLDSLGKQILPDWLTIEEHPHLLKGLASTPFDSEGVRTERRDIIKDG 322 Query: 311 ILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYY 370 IL + +L A K ++ GHA + N SFE+M++++ G Sbjct: 323 ILTQWLLTSYSARKLGLKSTGHAGG----------IHNWRIAGQGLSFEQMLKEMGTGLV 372 Query: 371 LVDFRG-GQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAI 429 + + G G + + + G G+ + NGEI P+ + +I G + + I VG D Sbjct: 373 VTELMGQGVSAITGDYSRG-AAGFWVENGEIQYPVSEITIAGNLKDMWRNIVTVGNDIET 431 Query: 430 ETGF-CG 435 + CG Sbjct: 432 RSNIQCG 438 >pir||B83086 PmbA protein PA4472 [imported] - Pseudomonas aeruginosa (strain PAO1) >gi|9950709|gb|AAG07860.1|AE004861_1 (AE004861) PmbA protein [Pseudomonas aeruginosa] Length = 449 Score = 70.2 bits (169), Expect = 4e-11 Identities = 95/410 (23%), Positives = 170/410 (41%), Gaps = 39/410 (9%) Query: 35 LTLKDGVFTSF------TEKLNR--GVAIRVLANGAWGFSSTSDLSK--LEEAIKEAYKL 84 ++L+ G+ TS T + NR G I + A G +STS + + E + A + Sbjct: 39 VSLEQGLSTSVRQGEVETVEFNRDQGFGITLYAGQRKGSASTSATGEAAIRETVAAALAI 98 Query: 85 AKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLTELEKLLKEDETVKSV 144 A+ SE E LA+ + + P + E+ V E+ L + + Sbjct: 99 ARHTSED--ECAGLADAALMARELPELDLYHPWSLSPEQAV------ERALACEAAAFAA 150 Query: 145 NIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGAV--DYGWEL 202 + R G L T++G R+ + ++ + Y + + M + G + DY +++ Sbjct: 151 DKRVTKADGTT-LNTHQGCRV-YGNSHGFIGGYASTRHSLSCVMIAEGEGQMQRDYWYDV 208 Query: 203 MTEKEP---NEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGP-IIVGLIAHEALGHLAEAD 258 E E + R + S+L + E PV+ P I VGL H LG ++ Sbjct: 209 NRRGEALASAESIGRRAAERAASRLGARPVQTAEVPVLFAPEIAVGLFGH-FLGAISGGS 267 Query: 259 LTMNSPFKD-LLGKQIAPEYVTMSER-YVEGGFGNDKYDDEGVPVKDIHIIENGILKEIM 316 L S F + LG+++ PE++++ ER ++ G G+ +D +G+ +ENG L + Sbjct: 268 LYRKSSFLEGALGQRLFPEWLSIDERPHLVGALGSASFDSDGLATYAKPFVENGELVSYV 327 Query: 317 LNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFRG 376 L K + +A + N GD +I ++ G + + G Sbjct: 328 LGTYSGRKLGLPSTANAGG----------VHNLFVSHGDEDQAALIRRMERGLLVTELMG 377 Query: 377 GQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKD 426 L + GY + NGEI P+++ +I + ++I AVGKD Sbjct: 378 QGVNLVTGDYSRGAAGYWVENGEIQFPVQEVTIAANLRDLFRRIVAVGKD 427 >pir||B69009 conserved hypothetical protein MTH1070 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622168|gb|AAB85559.1| (AE000877) conserved protein [Methanobacterium thermoautotrophicum] Length = 430 Score = 69.1 bits (166), Expect = 1e-10 Identities = 88/386 (22%), Positives = 159/386 (40%), Gaps = 43/386 (11%) Query: 52 GVAIRVLANGAWGFSSTSDLSKLEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSK 111 G+ IR+L G GF+ TSD ++ A++ A + ++LA+ P E+F S+ Sbjct: 48 GIGIRILKEGRMGFAYTSDPDGVDVAVRMA-----------AQNLQLAD--PDENFGFSE 94 Query: 112 MKVKPREVDIEEKVKHLTELEKLLKEDETVKSVNIRYEDG-----GG------QKILLTN 160 P I ++ E+E + + + +N E+G GG + +L + Sbjct: 95 PSTYPSVKGIHDRSFDDLEVEDSV--EMAGRMINRVLEEGCKPTSGGFTASRIETFILNS 152 Query: 161 EGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKL 220 EG + VT + G A +S D +L E V R R Sbjct: 153 EGVEESSSSTGFSAHISVTAGENGMKTTAYES----DSSCKLDINPE---WVAGRACRIA 205 Query: 221 HSQLNGVAPKRGEFPVVAG-PIIVGLIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVT 279 + G + + G P V GL+ A A+ S D +G Q+ E ++ Sbjct: 206 RDSMGGRSIESGRIPAVLDYHAAAGLLGTFAGAFSADNVQRGRSVLADRIGSQVTGEGLS 265 Query: 280 M-SERYVEGGFGNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDY 338 + + +EGG G+ +D EG P + ++E+GIL+ M N A+K + G+ + Y Sbjct: 266 VYDDGTLEGGLGSAPFDGEGTPSQRTALVEDGILRGYMHNIYTASKGRADSTGNG-LRGY 324 Query: 339 RYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFRGGQA--QLNSAFQVGIQEGYVIR 396 P + N + E + ++D + G ++ D G ++ F V ++ Sbjct: 325 MEVPAVSTTNFILE---FDSTVPLDDFR-GIFVTDVLGAHTANPISGDFSVEANNAFMAD 380 Query: 397 NGEIAEPIRDTSITGVAIEALKKISA 422 +GE P++ ++G E + K+S+ Sbjct: 381 SGEFT-PVKKAMLSGNIFELMMKVSS 405 Database: ./suso.pep Posted date: Jul 6, 2001 5:57 PM Number of letters in database: 840,471 Number of sequences in database: 2977 Database: /banques/blast2/nr.pep Posted date: Dec 14, 2000 12:46 PM Number of letters in database: 188,266,275 Number of sequences in database: 595,510 Lambda K H 0.315 0.136 0.388 Gapped Lambda K H 0.270 0.0470 0.230 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 174263123 Number of Sequences: 2977 Number of extensions: 7730745 Number of successful extensions: 24565 Number of sequences better than 1.0e-10: 46 Number of HSP's better than 0.0 without gapping: 15 Number of HSP's successfully gapped in prelim test: 31 Number of HSP's that attempted gapping in prelim test: 24418 Number of HSP's gapped (non-prelim): 51 length of query: 458 length of database: 189,106,746 effective HSP length: 58 effective length of query: 400 effective length of database: 154,394,500 effective search space: 61757800000 effective search space used: 61757800000 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.8 bits) X3: 64 (24.9 bits) S1: 42 (22.0 bits) S2: 166 (69.1 bits)