BLASTP 2.0.10 [Aug-26-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= PAB1955 (tldD-like) DE:TLDD RELATED PROTEIN
         (458 letters)

Database: ./suso.pep; /banques/blast2/nr.pep
           598,487 sequences; 189,106,746 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

pir||C75180 tldd related protein PAB1955 - Pyrococcus abyssi (st...   923  0.0
pir||E71033 tldD-related protein PH1557 - Pyrococcus horikoshii ...   862  0.0
pir||G71248 tldD homolog PH0246 - Pyrococcus horikoshii >gi|3256...   307  2e-82
sp|Q58403|Y996_METJA HYPOTHETICAL PROTEIN MJ0996 >gi|2826357|gb|...   290  2e-77
pir||A75213 tldd protein PAB0154 - Pyrococcus abyssi (strain Ors...   290  2e-77
pir||D64424 tldD homolog MJ0996 - Methanococcus jannaschii            288  7e-77
emb|CAB57642.1| (Y18930) hypothetical protein [Sulfolobus solfat...   249  4e-65
gb|AAK40965.1| Zn-dependent protease, tldD protein homolog, puta...   249  4e-65
sp|O26944|Y856_METTH HYPOTHETICAL PROTEIN MTH856 >gi|7429832|pir...   239  6e-62
pir||G75033 hypothetical protein PAB1547 - Pyrococcus abyssi (st...   232  6e-60
pir||D71135 tldD-related protein PH0848 - Pyrococcus horikoshii ...   228  8e-59
pir||D72762 hypothetical protein APE0089 - Aeropyrum pernix (str...   194  2e-48
sp|P73754|Y863_SYNY3 HYPOTHETICAL 50.4 KD PROTEIN SLR0863 >gi|74...   192  9e-48
gi|11498263 conserved hypothetical protein [Archaeoglobus fulgid...   180  4e-44
sp|P46473|TLDD_ECOLI TLDD PROTEIN >gi|7429829|pir||F65116 tldD p...   159  5e-38
gb|AAK41402.1| Conserved hypothetical protein [Sulfolobus solfat...   158  1e-37
sp|P57478|TLDD_BUCAI TLDD PROTEIN HOMOLOG >gi|10039067|dbj|BAB13...   153  3e-36
pir||D72342 tldD protein - Thermotoga maritima (strain MSB8) >gi...   153  5e-36
pir||G82325 tldD protein VC0422 [imported] - Vibrio cholerae (gr...   151  2e-35
sp|P74002|YD22_SYNY3 HYPOTHETICAL 53.1 KD PROTEIN SLR1322 >gi|74...   148  9e-35
emb|CAC11942.1| (AL445065) conserved hypothetical protein [Therm...   145  8e-34
pir||F82718 TldD protein XF1127 [imported] - Xylella fastidiosa ...   143  4e-33
sp|P45297|TLDD_HAEIN TLDD PROTEIN HOMOLOG                             141  1e-32
pir||D83086 conserved hypothetical protein PA4474 [imported] - P...   139  8e-32
gb|AAC43985.2| (U33883) TldD [Bradyrhizobium japonicum]               133  4e-30
pir||G70473 tldD homolog - Aquifex aeolicus >gi|2984257|gb|AAC07...   127  2e-28
pir||A82033 TLDD protein homolog NMA0367 [imported] - Neisseria ...   125  1e-27
pir||F81010 tldD protein NMB2066 [imported] - Neisseria meningit...   124  2e-27
pir||E72342 pmbA-related protein - Thermotoga maritima (strain M...   117  2e-25
dbj|BAB05755.1| (AP001514) suppressor of the inhibitory activity...   112  7e-24
pir||S70839 tldD homolog - Bradyrhizobium japonicum (fragment)        107  2e-22
pir||D70703 tldD homolog Rv2315c - Mycobacterium tuberculosis (s...    99  1e-19
gb|AAD53904.1|AF176314_14 (AF176314) PmbA [Zymomonas mobilis]          91  2e-17
pir||F71033 hypothetical protein PH1558 - Pyrococcus horikoshii ...    91  3e-17
pir||D82066 pmbA protein VC2535 [imported] - Vibrio cholerae (gr...    89  1e-16
pir||B75213 pmba protein (tlde protein) PAB0155 - Pyrococcus aby...    87  5e-16
pir||B75180 antibiotic/peptide maturation related protein PAB195...    84  3e-15
pir||B83330 hypothetical protein PA2529 [imported] - Pseudomonas...    83  6e-15
pir||T36780 hypothetical protein SCI28.10 - Streptomyces coelico...    83  8e-15
pir||E71135 hypothetical protein PH0849 - Pyrococcus horikoshii ...    80  4e-14
pir||F75033 hypothetical protein PAB1548 - Pyrococcus abyssi (st...    80  5e-14
pir||S77207 hypothetical protein slr1435 - Synechocystis sp. (st...    80  7e-14
sp|P45077|PMBA_HAEIN PMBA PROTEIN HOMOLOG >gi|1075002|pir||C6418...    79  1e-13
sp|P24231|PMBA_ECOLI PMBA PROTEIN (TLDE PROTEIN) >gi|96308|pir||...    75  2e-12
pir||B83086 PmbA protein PA4472 [imported] - Pseudomonas aerugin...    70  4e-11
pir||B69009 conserved hypothetical protein MTH1070 - Methanobact...    69  1e-10

>pir||C75180 tldd related protein PAB1955 - Pyrococcus abyssi (strain Orsay)
           >gi|5458032|emb|CAB49522.1| (AJ248284) TLDD RELATED
           PROTEIN [Pyrococcus abyssi]
           Length = 458
           
 Score =  923 bits (2360), Expect = 0.0
 Identities = 458/458 (100%), Positives = 458/458 (100%)

Query: 1   MMNMESLEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLAN 60
           MMNMESLEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLAN
Sbjct: 1   MMNMESLEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLAN 60

Query: 61  GAWGFSSTSDLSKLEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVD 120
           GAWGFSSTSDLSKLEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVD
Sbjct: 61  GAWGFSSTSDLSKLEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVD 120

Query: 121 IEEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTG 180
           IEEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTG
Sbjct: 121 IEEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTG 180

Query: 181 KKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGP 240
           KKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGP
Sbjct: 181 KKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGP 240

Query: 241 IIVGLIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSERYVEGGFGNDKYDDEGVP 300
           IIVGLIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSERYVEGGFGNDKYDDEGVP
Sbjct: 241 IIVGLIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSERYVEGGFGNDKYDDEGVP 300

Query: 301 VKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEE 360
           VKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEE
Sbjct: 301 VKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEE 360

Query: 361 MIEDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKI 420
           MIEDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKI
Sbjct: 361 MIEDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKI 420

Query: 421 SAVGKDFAIETGFCGKGQIAFVSSGGPHMRFDGGIIIG 458
           SAVGKDFAIETGFCGKGQIAFVSSGGPHMRFDGGIIIG
Sbjct: 421 SAVGKDFAIETGFCGKGQIAFVSSGGPHMRFDGGIIIG 458


>pir||E71033 tldD-related protein PH1557 - Pyrococcus horikoshii
           >gi|3257986|dbj|BAA30669.1| (AP000006) 458aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 458
           
 Score =  862 bits (2202), Expect = 0.0
 Identities = 417/458 (91%), Positives = 440/458 (96%)

Query: 1   MMNMESLEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLAN 60
           M+ ME+LEKAL+WAEENIKAEYIELRYED+KRT L LKDGVF +FTEKLNRGVAIRVL N
Sbjct: 1   MVPMEALEKALRWAEENIKAEYIELRYEDIKRTALNLKDGVFVNFTEKLNRGVAIRVLVN 60

Query: 61  GAWGFSSTSDLSKLEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVD 120
           GAWGFSSTS+L K+EEAIKEAYKLAK ASETKKEKI+LAEIKPVEDFVKSKMK+KPREVD
Sbjct: 61  GAWGFSSTSELDKVEEAIKEAYKLAKVASETKKEKIKLAEIKPVEDFVKSKMKIKPREVD 120

Query: 121 IEEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTG 180
           IEEK+ HL ELE LLKED+ VKSVNIRYEDGGGQKILLTNEGT+IEWDYNYLWQ VYVTG
Sbjct: 121 IEEKINHLKELENLLKEDKAVKSVNIRYEDGGGQKILLTNEGTKIEWDYNYLWQGVYVTG 180

Query: 181 KKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGP 240
           K++GKLAMARD+IGAVDYGWELMTEKEPNEKV+DR+LRKLHSQL G+ PKRGEFPVVAGP
Sbjct: 181 KEDGKLAMARDTIGAVDYGWELMTEKEPNEKVRDRILRKLHSQLKGITPKRGEFPVVAGP 240

Query: 241 IIVGLIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSERYVEGGFGNDKYDDEGVP 300
           IIVG+IAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSER+VEGGFGNDKYDDEGVP
Sbjct: 241 IIVGIIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSERHVEGGFGNDKYDDEGVP 300

Query: 301 VKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEE 360
           V+DIHIIENGILKEIMLNREYA KFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEE
Sbjct: 301 VRDIHIIENGILKEIMLNREYATKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEE 360

Query: 361 MIEDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKI 420
           MIEDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKI
Sbjct: 361 MIEDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKI 420

Query: 421 SAVGKDFAIETGFCGKGQIAFVSSGGPHMRFDGGIIIG 458
           +AVGKDF IE GFCGKGQ AFVSSGGPHMRF+GGIIIG
Sbjct: 421 TAVGKDFGIEVGFCGKGQTAFVSSGGPHMRFEGGIIIG 458


>pir||G71248 tldD homolog PH0246 - Pyrococcus horikoshii
           >gi|3256635|dbj|BAA29318.1| (AP000001) 504aa long
           hypothetical tldd protein [Pyrococcus horikoshii]
           Length = 504
           
 Score =  307 bits (777), Expect = 2e-82
 Identities = 172/454 (37%), Positives = 271/454 (58%), Gaps = 13/454 (2%)

Query: 1   MMNMESLEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLAN 60
           ++ ++ + K L+    + + +++++R E ++ T LT+++G   +      RGV +RVL N
Sbjct: 49  LIMIDEILKVLEKYSSSSEIKFMDIRMESIEYTELTIENGKVENLENNGERGVGVRVLIN 108

Query: 61  GAWGFSSTSDLSKLEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVD 120
           G WGF+ST+DL+K+EE +K A K+AK      +    +    P+ED V+ K  +K +++D
Sbjct: 109 G-WGFASTNDLTKIEEIVKTAIKMAK----VSRISTSVYTRDPIEDNVEVKQGIKLKDID 163

Query: 121 IEEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTG 180
           +EEKVK   E+  +LK  E +K+    Y D   +K+ L++EG+ IE     ++ S+    
Sbjct: 164 LEEKVKLGVEVNNMLKR-ENIKTRKFSYSDIIVKKLYLSSEGSIIESTVPRVYLSISSVA 222

Query: 181 KKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGP 240
           K  GK+     S G    GWE++ EK   E   + + +K  S L+  +P  GE  V+  P
Sbjct: 223 KFSGKMQTYWKSFGGTG-GWEIV-EKIDFEHWANFVSKKAVSLLSARSPPSGEMQVIMDP 280

Query: 241 IIVGLIAHEALGHLAEADLTMN--SPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDE 297
            + G+  HEALGH +EAD      S    +LGK+IA E +T+  +  + G FG+  YDDE
Sbjct: 281 ELAGVFIHEALGHASEADAVKQEESILAGMLGKRIAVEELTVVDDPTLPGKFGSYIYDDE 340

Query: 298 GVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWS 357
           G+P K + II +G+L   + +RE ++  N+EPNGH RAQ Y + P++RM NT  EPGDW 
Sbjct: 341 GIPGKRVEIIRDGVLVNYLNDRETSSLLNLEPNGHGRAQSYSHVPLVRMSNTYIEPGDWR 400

Query: 358 FEEMIEDIKFGYYLVDFRGGQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEA 416
           FEE+++++KFG Y++  +GGQ  + S  F    +EGY++ NGEI   +RD +++G  + A
Sbjct: 401 FEEILDEVKFGVYMIGDKGGQVDVASGNFMFAAKEGYLVENGEIKGHLRDVALSGNILSA 460

Query: 417 LKKISAVGKDFAIE-TGFCGKGQIAFVSSGGPHM 449
           L++I A+G D  IE  GFCGKGQ   V  GGPH+
Sbjct: 461 LREIKAIGNDLKIEFPGFCGKGQWVPVDDGGPHV 494


>sp|Q58403|Y996_METJA HYPOTHETICAL PROTEIN MJ0996 >gi|2826357|gb|AAB99001.1| (U67542)
           conserved hypothetical protein [Methanococcus
           jannaschii]
           Length = 451
           
 Score =  290 bits (735), Expect = 2e-77
 Identities = 174/459 (37%), Positives = 267/459 (57%), Gaps = 23/459 (5%)

Query: 1   MMNMESLEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLAN 60
           M+N+E +EK L+        +Y ++R    +  T+TLKDG     +     GVA+RVL  
Sbjct: 1   MLNLEKIEKLLE------VGDYADIRINFGESNTITLKDGKIEEISSGFGNGVAVRVLYK 54

Query: 61  GAWGFSSTSDLSK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPRE 118
             WGF +++ +S+  +E+ I +AYK+AK ++E  +++I L + K + D  K   K+ P +
Sbjct: 55  NGWGFVTSNIVSEEEIEKLINKAYKMAKISNEYSEKEIILKDYKAIIDNYKMIGKINPTD 114

Query: 119 VDIEEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYV 178
           VDIEEK + + +  K +  DE +KS+++ Y D  G++I + +EG+RIE +       +  
Sbjct: 115 VDIEEKKEIIIDTYKNMT-DEKIKSISVSYSDVFGKRIFMISEGSRIEGEITRCIMYMNC 173

Query: 179 TGKKEGKLAMARDSIGAVDYGWELMTEKEPNE--KVKDRLLRKLHSQLNGVAPKRGEFPV 236
             K+ G L    +  G   +G+E + +   N   + K+R LR L ++     PK G+F V
Sbjct: 174 VAKENGNLQYGAERTGG--FGFEKIKDNYLNLALEAKNRALRLLKAK---PCPK-GKFKV 227

Query: 237 VAGPIIVGLIAHEALGHLAEADLTM--NSPFKDLLGKQIAPEYVTM-SERYVEGGFGNDK 293
           +  P + G+  HEA+GH +EADL +  +S FKD LG+++  EYVT+  +  +EG FG+ K
Sbjct: 228 ILDPELAGVFIHEAVGHASEADLVLQNDSVFKDKLGERVGSEYVTVIDDATIEGAFGSYK 287

Query: 294 YDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEP 353
           YDDEGV  K   IIENGILK  + +RE A + + E  G+ RA+     PI+RM NT  +P
Sbjct: 288 YDDEGVEGKKTVIIENGILKTYLHSRETAGRMDAELTGNGRAEGLN-KPIVRMSNTFIKP 346

Query: 354 GDWSFEEMIEDIKFGYYLVDFRGGQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGV 412
           GDWSFEE++ED K G +L   RGGQ       FQ    E Y+I NGE+ + ++D  ++G 
Sbjct: 347 GDWSFEELLEDTKEGIFLKGSRGGQVDTGKGLFQFSAVEAYLIENGELTQVLKDAGLSGE 406

Query: 413 AIEALKKISAVGKDFAIETGFCGK-GQIAFVSSGGPHMR 450
            ++ L K+ AV KDF +  G+CGK GQ   V  GG  +R
Sbjct: 407 ILDILFKVDAVTKDFELSVGYCGKDGQSVPVGDGGGCVR 445


>pir||A75213 tldd protein PAB0154 - Pyrococcus abyssi (strain Orsay)
           >gi|5457661|emb|CAB49152.1| (AJ248283) TLDD PROTEIN
           [Pyrococcus abyssi]
           Length = 452
           
 Score =  290 bits (735), Expect = 2e-77
 Identities = 167/436 (38%), Positives = 253/436 (57%), Gaps = 13/436 (2%)

Query: 19  KAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAI 78
           + +++++R+E+   T  T+++G           G+ +RVL NG WGF+ST+DLSKLE+ I
Sbjct: 15  EVKFMDIRFENTIYTEFTVENGKVEGVESNEEVGIGVRVLING-WGFASTNDLSKLEDTI 73

Query: 79  KEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLTELEKLLKED 138
           K A KLAK ++     ++ L    PVE     K K    +VD+EEK K   E+EK+++ D
Sbjct: 74  KMAIKLAKVSNA----EVPLYVGNPVEGKAIIKQKKDFLDVDLEEKTKLGLEVEKMIRRD 129

Query: 139 ETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGAVDY 198
           + +K+    Y D   +KI L +EG+ IE     ++ S+    +    +     S G    
Sbjct: 130 K-IKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSADIMQTYWKSFGGT-V 187

Query: 199 GWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAEAD 258
           GWEL+   + N    + +  K  S L+  +P  GE P++  P + G+  HEALGH  EAD
Sbjct: 188 GWELVESVDFNYWA-NFISSKALSLLSARSPPSGEMPIIMDPELAGVFIHEALGHAVEAD 246

Query: 259 LTMN--SPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPVKDIHIIENGILKEI 315
                 S    ++GK+I  E +T+  +  + G FG+  YDDEG+P K + II++G+L   
Sbjct: 247 SVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGKRVEIIKDGVLLNY 306

Query: 316 MLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFR 375
           + +RE +   N+ PNGH RAQ Y + P++RM NT   PG+W+ EEM E++KFG Y++  +
Sbjct: 307 LNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMFEEVKFGVYMIGDK 366

Query: 376 GGQAQL-NSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAIE-TGF 433
           GGQ  + N +F  G +EGY+I+ GEI E +RD  I+G  ++ LK+I AVG+D  IE  GF
Sbjct: 367 GGQVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEIKAVGRDLKIEFPGF 426

Query: 434 CGKGQIAFVSSGGPHM 449
           CGKGQ   V  GGPH+
Sbjct: 427 CGKGQWVPVDDGGPHV 442


>pir||D64424 tldD homolog MJ0996 - Methanococcus jannaschii
           Length = 451
           
 Score =  288 bits (730), Expect = 7e-77
 Identities = 173/459 (37%), Positives = 266/459 (57%), Gaps = 23/459 (5%)

Query: 1   MMNMESLEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLAN 60
           M+N+E +EK L+        +Y ++R    +  T+TLKDG     +     GVA+RVL  
Sbjct: 1   MLNLEKIEKLLE------VGDYADIRINFGESNTITLKDGKIEEISSGFGNGVAVRVLYK 54

Query: 61  GAWGFSSTSDLSK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPRE 118
             WGF +++ +S+  +E+ I +AYK+AK ++E  +++  L + K + D  K   K+ P +
Sbjct: 55  NGWGFVTSNIVSEEEIEKLINKAYKMAKISNEYSEKEXILKDYKAIIDNYKMIGKINPTD 114

Query: 119 VDIEEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYV 178
           VDIEEK + + +  K +  DE +KS+++ Y D  G++I + +EG+RIE +       +  
Sbjct: 115 VDIEEKKEIIIDTYKNMT-DEKIKSISVSYSDVFGKRIFMISEGSRIEGEITRCIMYMNC 173

Query: 179 TGKKEGKLAMARDSIGAVDYGWELMTEKEPNE--KVKDRLLRKLHSQLNGVAPKRGEFPV 236
             K+ G L    +  G   +G+E + +   N   + K+R LR L ++     PK G+F V
Sbjct: 174 VAKENGNLQYGAERTGG--FGFEKIKDNYLNLALEAKNRALRLLKAK---PCPK-GKFKV 227

Query: 237 VAGPIIVGLIAHEALGHLAEADLTM--NSPFKDLLGKQIAPEYVTM-SERYVEGGFGNDK 293
           +  P + G+  HEA+GH +EADL +  +S FKD LG+++  EYVT+  +  +EG FG+ K
Sbjct: 228 ILDPELAGVFIHEAVGHASEADLVLQNDSVFKDKLGERVGSEYVTVIDDATIEGAFGSYK 287

Query: 294 YDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEP 353
           YDDEGV  K   IIENGILK  + +RE A + + E  G+ RA+     PI+RM NT  +P
Sbjct: 288 YDDEGVEGKKTVIIENGILKTYLHSRETAGRMDAELTGNGRAEGLN-KPIVRMSNTFIKP 346

Query: 354 GDWSFEEMIEDIKFGYYLVDFRGGQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGV 412
           GDWSFEE++ED K G +L   RGGQ       FQ    E Y+I NGE+ + ++D  ++G 
Sbjct: 347 GDWSFEELLEDTKEGIFLKGSRGGQVDTGKGLFQFSAVEAYLIENGELTQVLKDAGLSGE 406

Query: 413 AIEALKKISAVGKDFAIETGFCGK-GQIAFVSSGGPHMR 450
            ++ L K+ AV KDF +  G+CGK GQ   V  GG  +R
Sbjct: 407 ILDILFKVDAVTKDFELSVGYCGKDGQSVPVGDGGGCVR 445


>emb|CAB57642.1| (Y18930) hypothetical protein [Sulfolobus solfataricus]
           Length = 443
           
 Score =  249 bits (630), Expect = 4e-65
 Identities = 159/449 (35%), Positives = 243/449 (53%), Gaps = 25/449 (5%)

Query: 9   KALKWAEENIKAEYIELRYEDLKRTTLTL-KDGVFTSFTEKLNRGVAIRVLANGAWGFSS 67
           K +K AEE + A + ++RYE +    +T+ +D  + S    ++ G +IRV+ N  WGF +
Sbjct: 3   KYIKKAEE-LGASFADIRYERVIANEVTITEDRKYVS--HGVDEGYSIRVIYNRNWGFKA 59

Query: 68  TSDLSK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKV 125
           T  +++  +E+ I   Y           E++ +  +    D +K    +   E   EEK+
Sbjct: 60  TDKITENEIEDTINHIYG---------DERVNIVYLPSKHDTIKIGKDINKNE---EEKI 107

Query: 126 KHLTELEKLLKE-DETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEG 184
             L ++   +     ++KS +I+Y D    K   ++E   I  D +    S+ V  + EG
Sbjct: 108 NDLHKVASQVNTLHPSIKSYSIKYYDEIFHKEYYSSEDREIIADGSSSSLSILVVAR-EG 166

Query: 185 KLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVG 244
            + +    I +   G+  + +     +V   L +++ +QL G  PK GE+PV+  P +VG
Sbjct: 167 DVTVEVSEILSTQMGY--IFDVFDINQVLANLQKRIINQLKGSTPKAGEYPVILAPEVVG 224

Query: 245 LIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSERYVEGGFGNDK--YDDEGVPVK 302
           +  HEA+GHL+EAD+T+N     L  K+I  E++ +S+        +    YDDEGV  +
Sbjct: 225 IFTHEAIGHLSEADVTLNGSLYKLRNKRIGDEFLNISDLPAMDHPQSSLVYYDDEGVEGR 284

Query: 303 DIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMI 362
           ++ IIENGILKE M +R Y+A     P G+ARAQ YR   +IRMRNT  +PGD S  E+ 
Sbjct: 285 EVKIIENGILKEFMTDRYYSAYLGQPPTGNARAQSYRNFSLIRMRNTYMKPGDASLNELF 344

Query: 363 EDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISA 422
           E IK GYYLV   GG+   N  FQ  IQEGY + N EI EP+R+  I+G  I  L  I  
Sbjct: 345 EGIKEGYYLVSPIGGETSSNGTFQFAIQEGYRVENSEIKEPLRNIGISGNTISTLNAIEM 404

Query: 423 VGKDFAIETGFCGK-GQIAFVSSGGPHMR 450
           + KDF + +GFC K GQ   VS+GGPH++
Sbjct: 405 ISKDFGMSSGFCEKNGQTVQVSNGGPHIK 433


>gb|AAK40965.1| Zn-dependent protease, tldD protein homolog, putative (tldD)
           [Sulfolobus solfataricus]
           Length = 443
           
 Score =  249 bits (630), Expect = 4e-65
 Identities = 159/449 (35%), Positives = 243/449 (53%), Gaps = 25/449 (5%)

Query: 9   KALKWAEENIKAEYIELRYEDLKRTTLTL-KDGVFTSFTEKLNRGVAIRVLANGAWGFSS 67
           K +K AEE + A + ++RYE +    +T+ +D  + S    ++ G +IRV+ N  WGF +
Sbjct: 3   KYIKKAEE-LGASFADIRYERVIANEVTITEDRKYVS--HGVDEGYSIRVIYNRNWGFKA 59

Query: 68  TSDLSK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKV 125
           T  +++  +E+ I   Y           E++ +  +    D +K    +   E   EEK+
Sbjct: 60  TDKITENEIEDTINHIYG---------DERVNIVYLPSKHDTIKIGKDINKNE---EEKI 107

Query: 126 KHLTELEKLLKE-DETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEG 184
             L ++   +     ++KS +I+Y D    K   ++E   I  D +    S+ V  + EG
Sbjct: 108 NDLHKVASQVNTLHPSIKSYSIKYYDEIFHKEYYSSEDREIIADGSSSSLSILVVAR-EG 166

Query: 185 KLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVG 244
            + +    I +   G+  + +     +V   L +++ +QL G  PK GE+PV+  P +VG
Sbjct: 167 DVTVEVSEILSTQMGY--IFDVFDINQVLANLQKRIINQLKGSTPKAGEYPVILAPEVVG 224

Query: 245 LIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSERYVEGGFGNDK--YDDEGVPVK 302
           +  HEA+GHL+EAD+T+N     L  K+I  E++ +S+        +    YDDEGV  +
Sbjct: 225 IFTHEAIGHLSEADVTLNGSLYKLRNKRIGDEFLNISDLPAMDHPQSSLVYYDDEGVEGR 284

Query: 303 DIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMI 362
           ++ IIENGILKE M +R Y+A     P G+ARAQ YR   +IRMRNT  +PGD S  E+ 
Sbjct: 285 EVKIIENGILKEFMTDRYYSAYLGQPPTGNARAQSYRNFSLIRMRNTYMKPGDASLNELF 344

Query: 363 EDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISA 422
           E IK GYYLV   GG+   N  FQ  IQEGY + N EI EP+R+  I+G  I  L  I  
Sbjct: 345 EGIKEGYYLVSPIGGETSSNGTFQFAIQEGYRVENSEIKEPLRNIGISGNTISTLNAIEM 404

Query: 423 VGKDFAIETGFCGK-GQIAFVSSGGPHMR 450
           + KDF + +GFC K GQ   VS+GGPH++
Sbjct: 405 ISKDFGMSSGFCEKNGQTVQVSNGGPHIK 433


>sp|O26944|Y856_METTH HYPOTHETICAL PROTEIN MTH856 >gi|7429832|pir||C69214 zinc
           metalloproteinase - Methanobacterium thermoautotrophicum
           (strain Delta H) >gi|2621948|gb|AAB85354.1| (AE000862)
           zinc metalloproteinase [Methanobacterium
           thermoautotrophicum]
           Length = 454
           
 Score =  239 bits (603), Expect = 6e-62
 Identities = 152/444 (34%), Positives = 228/444 (51%), Gaps = 12/444 (2%)

Query: 19  KAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAI 78
           + EY ++R    + +++ +KDG           G  IRVL NG+WGF+ T + S+L E  
Sbjct: 18  RVEYADIRAGTSRTSSILMKDGKLQEVKSGRASGFRIRVLRNGSWGFAFTDEPSRLGEMA 77

Query: 79  KEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLTELEKLLKED 138
            +A K+  S     +  +++    P  D    +    P +V   EK + +++       D
Sbjct: 78  LKAIKMTGSL----RGDVQVGSGAPSVDKTMVRSSRPPSDVPAAEKRELVSDAHHAASVD 133

Query: 139 ETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGAVDY 198
             V S  + Y D       L +EG+ IE     +   +         +     S G    
Sbjct: 134 GVV-STTVSYVDMESSSAFLNSEGSLIEMAETRVALFLNAVASDGSGIQFGHKSCGGTG- 191

Query: 199 GWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAEAD 258
           G+E++ E+E  E++  R   K    L    P  G F +V  P + G+  HEALGH AEAD
Sbjct: 192 GFEIL-EREDIEELGRRTGEKAVRLLKASPPPSGRFDIVTDPELTGVFIHEALGHAAEAD 250

Query: 259 LTM--NSPFKDLLGKQIAPEYVTMSERYVEGGFGNDKYDDEGVPVKDIHIIENGILKEIM 316
           L +  +S  +  LG++IA E VT+ +     GFG+  YD EGV   +  ++ENG+L  ++
Sbjct: 251 LILQGDSILEGKLGEKIASEGVTIIDDPTIDGFGSYSYDAEGVRAAETVLVENGVLTSLL 310

Query: 317 LNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFRG 376
            +RE A K  +EP+G+AR+      PI+RM NT  +PGD SF+E+IEDI+ G YL   RG
Sbjct: 311 NSRETAFKLGLEPSGNARSA-IGDQPIVRMSNTYLKPGDLSFDELIEDIRNGVYLRGSRG 369

Query: 377 GQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAIETGFCG 435
           GQ       FQ    E + I++GEIAEP++D S++G  +E LK +  VG DF +  GFCG
Sbjct: 370 GQVDTGKGIFQFNAAESFRIQDGEIAEPVKDVSLSGNVLETLKNVDGVGSDFRLGIGFCG 429

Query: 436 K-GQIAFVSSGGPHMRFDGGIIIG 458
           K GQ   V  GGPH+R    ++ G
Sbjct: 430 KSGQSVPVGDGGPHVRIRNAMVGG 453


>pir||G75033 hypothetical protein PAB1547 - Pyrococcus abyssi (strain Orsay)
           >gi|5458677|emb|CAB50164.1| (AJ248287) hypothetical
           protein [Pyrococcus abyssi]
           Length = 473
           
 Score =  232 bits (586), Expect = 6e-60
 Identities = 159/462 (34%), Positives = 239/462 (51%), Gaps = 22/462 (4%)

Query: 6   SLEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGF 65
           ++EKAL+     + A Y E R+E+ + T+L++K+GV        +RG+ IRVL +G  GF
Sbjct: 8   AVEKALE-----LGANYAEARFEEKQGTSLSMKNGVPQGMQLLSDRGIGIRVLVDGGMGF 62

Query: 66  SSTSDLSK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEE 123
           +ST+ L+K  + E ++ A KLAKSAS+ +KE I+ ++      + + KMK   R+V  EE
Sbjct: 63  ASTNILTKESIVETVQRAVKLAKSASKLRKEPIKFSDEYFHNVYYEVKMKKDFRDVPPEE 122

Query: 124 KVKHLTELEK-LLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKK 182
           K++ L ++E+ +L  +  V    + Y D    KI + +E   +E     +     +   +
Sbjct: 123 KLELLKKIEEEVLSTNVKVPMRYLAYSDHVWHKIFVNSENAVVESVIPRVSVMYNLVVYE 182

Query: 183 EGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPII 242
           EG++  A     A   G EL+ + EP E+ K  +         G  P  G+  +V  P +
Sbjct: 183 EGQMEQAPFVSRAFSGGLELIEKDEPWERAKKEVETLKRIITEGKKPPEGKVDLVISPEV 242

Query: 243 VGLIAHEALGHLAEADLTMNSPFK---------DLLGKQIAPEYVTM-SERYVEGGFGND 292
            G+  HE++GH  E D  M              D+LG++I  E VT+  +  +   +G  
Sbjct: 243 AGIAVHESVGHPYELDRIMGREAAQAGESFVKPDMLGERIGSEVVTVIDDPTIPNSWGFY 302

Query: 293 KYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFE 352
            YDDEGV  +  ++I NGI+ E ++NREYAAK  +  N  ARA +Y   PI+RM NT   
Sbjct: 303 LYDDEGVKARPRYLIRNGIITEFLMNREYAAKLGLRSNAAARAINYNREPIVRMANTYLA 362

Query: 353 PGDWSFEEMIEDIKFGYYLVDFRGGQAQLNSAFQVGI-QEGYVIRNGEIAEPIRDTSITG 411
           PGD+SFEE+IEDIK G Y+V F           Q  I +E Y+I NGEI  P++   +  
Sbjct: 363 PGDYSFEELIEDIKLGVYMVSFNEWNIDDRRYQQRYIGREAYLIENGEIKHPVKRPILEI 422

Query: 412 VAIEALKKISAVGKDFAIETGFCGK---GQIAFVSSGGPHMR 450
                   + AVGK+     G CGK   GQ   V  GG H R
Sbjct: 423 TTRGLWSSVDAVGKEVEFHPGTCGKGEPGQGVPVWMGGAHAR 464


>pir||D71135 tldD-related protein PH0848 - Pyrococcus horikoshii
           >gi|3257259|dbj|BAA29942.1| (AP000003) 481aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 481
           
 Score =  228 bits (576), Expect = 8e-59
 Identities = 160/466 (34%), Positives = 241/466 (51%), Gaps = 32/466 (6%)

Query: 11  LKWAEEN---IKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSS 67
           L++A EN   + A Y E R+E+ +  +L +K+G+        ++G+ +RVL NG  GF+S
Sbjct: 13  LEFAIENALELGASYAEARFEEKQGISLAMKNGIPEGMEILSDKGIGVRVLVNGGMGFAS 72

Query: 68  TSDLSK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKV 125
           T+ L+K  + E +K A KLAK+AS+ +KE I  +E      + + KMK   R+V  EEK+
Sbjct: 73  TNVLTKESIAETVKRAVKLAKAASKLRKEPITFSEEDFHNVYYEVKMKKDFRDVSPEEKL 132

Query: 126 KHLTELEKLLKEDETVKSVN-----IRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTG 180
               EL K ++E+ T  +VN     I Y D    K+ + +E  +IE     +     +  
Sbjct: 133 ----ELLKKIEEEVTSTNVNVPMRYIAYSDHVWHKVFMNSENAKIESLIPRVSVMYNLVV 188

Query: 181 KKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRL--LRKLHSQLNGVAPKRGEFPVVA 238
            + G++  A     A   G EL+ + EP E+ K  +  LRK+ ++  G     G+  V+ 
Sbjct: 189 FENGQMEQAPFIQRAFSGGLELIEKDEPWERAKREVETLRKIITE--GKRSPEGKVDVII 246

Query: 239 GPIIVGLIAHEALGHLAEADLTMNSPFK---------DLLGKQIAPEYVTM-SERYVEGG 288
            P + G+  HE++GH  E D  M              ++LG++I  E VT+  +  +   
Sbjct: 247 SPEVAGIAVHESVGHPYELDRIMGREAAQAGESFVKPEMLGERIGSEVVTVIDDPTIPNS 306

Query: 289 FGNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRN 348
           +G   YDDEGV  +  ++I NGI+ E ++NREYAAK  +  N  ARA +Y   PI+RM N
Sbjct: 307 WGFYLYDDEGVKARPRYLIRNGIITEFLMNREYAAKLGLRSNAAARAINYNREPIVRMAN 366

Query: 349 TVFEPGDWSFEEMIEDIKFGYYLVDFRGGQAQLNSAFQVGI-QEGYVIRNGEIAEPIRDT 407
           T   PGD+SFEE+IED+K G Y+V F           Q  I +E Y+I NGEI  P++  
Sbjct: 367 TYLAPGDYSFEELIEDVKLGVYMVSFNEWNIDDRRYQQRYIGREAYLIENGEIKHPVKRP 426

Query: 408 SITGVAIEALKKISAVGKDFAIETGFCGK---GQIAFVSSGGPHMR 450
            +          + AVGK+     G CGK   GQ   V  GG H R
Sbjct: 427 ILEITTRGLWSSVDAVGKEVEFYAGTCGKGEPGQGVPVWMGGAHAR 472


>pir||D72762 hypothetical protein APE0089 - Aeropyrum pernix (strain K1)
           >gi|5103477|dbj|BAA78998.1| (AP000058) 489aa long
           hypothetical protein [Aeropyrum pernix]
           Length = 489
           
 Score =  194 bits (487), Expect = 2e-48
 Identities = 152/469 (32%), Positives = 237/469 (50%), Gaps = 37/469 (7%)

Query: 7   LEKALKWAEENIKAEYIELRYED-LKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGF 65
           LEK ++ A +   A Y E R+   L  + L + D V     E +  GVA RV+ +GA GF
Sbjct: 26  LEKLVEKALDK-GASYAEARFHARLGDSVLVVNDRVVGGGFE-IEEGVAFRVIVDGALGF 83

Query: 66  SSTSDLSK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEE 123
           +STS LS+  L+  +  A  +A+S+S   ++K+ ++E +  +     K+K   R +++E+
Sbjct: 84  ASTSLLSEESLDSVVDHAVSIARSSSRGFRKKVGMSEERLGQAQYSLKVKKDFRNLELED 143

Query: 124 KVKHLTELEKLLKEDET-VKSVNIRYEDGGGQKILLTNEGTRIEWD-------YNYLWQS 175
           K   + E  K L+     +K+    Y D    K+++T++G  IE         YN   + 
Sbjct: 144 KASIVLEYSKSLESKSVDLKAKTFSYSDVLEAKLIITSDGGNIESIIPRVSIFYNIAAEH 203

Query: 176 VYVTGKKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFP 235
                 K G LA +         G EL+ E      +KD +     + +      +G   
Sbjct: 204 GDRRANKWGHLAGSG--------GLELVGELGLESMLKDDVNSLEVNLVKAEPSPKGVMD 255

Query: 236 VVAGPIIVGLIAHEALGHLAEADLTMNSP-------FKDLLGKQIAPEYVTMSER-YVEG 287
           V+  P IVGL  HE++GH +EAD  M          ++  L  +I    VT+++   V G
Sbjct: 256 VIISPEIVGLALHESIGHPSEADRVMGREAAQAGLSYRMWLDGRIGSSKVTVADDPTVPG 315

Query: 288 GFGNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMR 347
            +G   YDDE VP ++  +I  G L E++ +R  A  F ++ NG ARA +YR  PI+RM 
Sbjct: 316 SYGFYLYDDEAVPARERILINKGELAELLHSRTTAYSFGVQSNGAARAMNYRSEPIVRMS 375

Query: 348 NTVFEPGDWSFEEMIEDIKFGYYL---VDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPI 404
           NT  +PGD  FEE++ED+K G Y+   +++   + +L + + VG+ E Y+I+NG I +P+
Sbjct: 376 NTYLKPGDMRFEELLEDVKEGIYMKSYMEWNIDEFRLVARY-VGL-EAYLIKNGRIVKPV 433

Query: 405 RDTSITGVAIEALKKISAVGKDFAIETGFCGKG---QIAFVSSGGPHMR 450
           RDT +         KI  VGKD     G CGKG   Q   V  GGPH+R
Sbjct: 434 RDTVLEIPTESFYSKIDGVGKDLRFYAGICGKGEPPQPLPVWMGGPHVR 482


>sp|P73754|Y863_SYNY3 HYPOTHETICAL 50.4 KD PROTEIN SLR0863 >gi|7429837|pir||S74845 tldD
           homolog slr0863 - Synechocystis sp. (strain PCC 6803)
           >gi|1652888|dbj|BAA17806.1| (D90909) hypothetical
           protein [Synechocystis sp.]
           Length = 463
           
 Score =  192 bits (482), Expect = 9e-48
 Identities = 131/450 (29%), Positives = 226/450 (50%), Gaps = 19/450 (4%)

Query: 19  KAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAI 78
           +A++I +R E  + T ++L+     + +E +  G  +RV   G WGF+S +   +L + +
Sbjct: 20  QADFISIRLEQSEGTQISLRSDQVETLSEGIAMGGQVRVCHQGGWGFASFNRWEQLRQRL 79

Query: 79  KEAYKLAKSASETKKEKIELAEIKPVED-FVKSKMKVKPREVDIEEKVKHLTELEKLLK- 136
           +EA   A+   +   ++  LA I PV+  F+       PR++ + +K         LL+ 
Sbjct: 80  EEAIAAARLIGD---DETLLAPIDPVQQTFINPLTGKDPRQISLADKKALCDHYNDLLRG 136

Query: 137 EDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGAV 196
             + + + ++RY D     +L T+EGT +E  +  L      T K    + + R++ G+ 
Sbjct: 137 TSDKITTTHVRYSDSQQTVLLATSEGTLLEQCWWDLEMRFAATAKDGNGVQVGRETTGSR 196

Query: 197 -DYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLA 255
             YG     + E  ++V     ++    L     +   +PVV  PI+ GL  HEA GHL+
Sbjct: 197 RGYG-----DLENLDQVVQGAAQRAVKALTLPTVQGKTYPVVIDPILTGLFVHEAFGHLS 251

Query: 256 EADLTMNSP-FKDL--LGKQIAPEYVTMSERYVEGGF-GNDKYDDEGVPVKDIHIIENGI 311
           EAD+   +P F ++  LG++  P  + + +     G  G+  +DDEGVP     +I++G 
Sbjct: 252 EADMLYENPDFLEVMSLGRRFGPPELQIFDGAAPPGHRGSYGFDDEGVPASTTQLIKDGE 311

Query: 312 LKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYL 371
           L   + +RE A K   +P G+AR  +Y YPPI+RM NT    G+     +++ I+ G Y 
Sbjct: 312 LVGRLHSRETAGKLGEKPTGNARCLNYHYPPIVRMTNTWIGRGETPVANLLDGIEEGIYA 371

Query: 372 VDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFA-IE 430
            ++ GG       F     E ++IR+G++AEP++D +++G   + L  I A+  DF   E
Sbjct: 372 QNWLGGMTN-GEMFTFSAGEAWMIRHGQLAEPVKDVTLSGNVFKTLANIEAIADDFYWDE 430

Query: 431 TGFCGKG--QIAFVSSGGPHMRFDGGIIIG 458
           +G CGKG      V  GGP +R    ++ G
Sbjct: 431 SGGCGKGGQNGLAVGCGGPSLRIRDVVVGG 460


>gi|11498263 conserved hypothetical protein [Archaeoglobus fulgidus]
           >gi|3123065|sp|O29602|Y655_ARCFU HYPOTHETICAL PROTEIN
           AF0655 >gi|7429834|pir||G69331 conserved hypothetical
           protein AF0655 - Archaeoglobus fulgidus
           >gi|2649963|gb|AAB90585.1| (AE001059) conserved
           hypothetical protein [Archaeoglobus fulgidus]
           Length = 425
           
 Score =  180 bits (451), Expect = 4e-44
 Identities = 134/436 (30%), Positives = 223/436 (50%), Gaps = 35/436 (8%)

Query: 25  LRYEDLKRT-----TLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAIK 79
           +R+ D++R       L L++G         +     RVL NG WG    +     +E ++
Sbjct: 1   MRFWDIRRVENVSLNLQLENGKLEKPRYNKSTSKGFRVLKNGFWGIFEGNVAD--DEGLR 58

Query: 80  EAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLTELEKLLKEDE 139
           +A K A +  +   E+I        +   + ++K  P+++ IEEKV+ L +LEK+++ D 
Sbjct: 59  QAEKNAFTQGDGDIEEIA------TKGRYRMRVKRDPQDMSIEEKVELLKDLEKIIR-DV 111

Query: 140 TVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGK----LAMARDSIGA 195
            V +  + +E+   +++L   +    E +Y  L   V + G  +G+    L+  +  +G 
Sbjct: 112 CVSTKLVYFEN---RRVLQYRDSCGSEVEYEVLRTGVSIMGVGKGRSLQFLSKRQMRVG- 167

Query: 196 VDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLA 255
              G+E++   +        +L KL   +N +AP  GE  VV    + G+  HEA GH  
Sbjct: 168 ---GYEVLDGVDEKAYEIVEVLPKL---VNALAPPSGEMSVVMDSSLAGVFVHEAFGHAV 221

Query: 256 EADLTMNSP--FKDLLGKQIAPEYVTMSERYVEGGFGNDKYDDEGVPVKDIHIIENGILK 313
           EAD  +      K  L +++A E VT+ +      FG   +DDEGV  +   I+E+G+LK
Sbjct: 222 EADHVLQGATVLKGRLNEKVADESVTIIDDPTLPEFGFFPFDDEGVRAEKKVIVEDGVLK 281

Query: 314 EIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVD 373
             + +RE A K      G+AR+Q    P I+RM NT  +   +SF+E++E+ + G YLV 
Sbjct: 282 SFLHSRETAKKLGGVA-GNARSQGVDVP-IVRMSNTYIDTHHYSFDELLEECRDGVYLVG 339

Query: 374 FRGGQAQ-LNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAIETG 432
            RGG+       F    Q GY+I+NGE+AE +RD S++G  +E L+ +  +G++   + G
Sbjct: 340 SRGGETNPATGYFHFNAQYGYLIKNGELAEMVRDVSLSGNTLEILRNVK-IGREIEFDPG 398

Query: 433 FCGK-GQIAFVSSGGP 447
           FCGK GQ+  VS G P
Sbjct: 399 FCGKAGQLVPVSDGSP 414


>sp|P46473|TLDD_ECOLI TLDD PROTEIN >gi|7429829|pir||F65116 tldD protein - Escherichia
           coli (strain K-12) >gi|606183|gb|AAA58046.1| (U18997)
           ORF_f481 [Escherichia coli] >gi|1732437|dbj|BAA07913.1|
           (D44451) TldD protein [Escherichia coli]
           >gi|1789640|gb|AAC76276.1| (AE000403) suppresses
           inhibitory activity of CsrA [Escherichia coli K12]
           Length = 481
           
 Score =  159 bits (399), Expect = 5e-38
 Identities = 123/448 (27%), Positives = 210/448 (46%), Gaps = 20/448 (4%)

Query: 19  KAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLS--KLEE 76
           + +Y +L ++     +  L+D +    +  +++GV +R ++    GF+    +S   LE+
Sbjct: 32  RLDYGDLYFQSSYHESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYADQISLLALEQ 91

Query: 77  AIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLTELEKLLK 136
           + + A  + + + + K + +   E  P+   V     +       EEK+  L  ++K+ +
Sbjct: 92  SAQAARTIVRDSGDGKVQTLGAVEHSPLYTSVDPLQSMSR-----EEKLDILRRVDKVAR 146

Query: 137 E-DETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGA 195
           E D+ V+ V           ++   +GT        +  SV V  +++GK        G 
Sbjct: 147 EADKRVQEVTASLSGVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGASG-GG 205

Query: 196 VDYGWELMTEKEPNEKVKD----RLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEAL 251
             +G+E        E   D      +R     L+ VA   G  PVV G    G++ HEA+
Sbjct: 206 GRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSAVAAPAGTMPVVLGAGWPGVLLHEAV 265

Query: 252 GHLAEADLTMN--SPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPVKDIHIIE 308
           GH  E D      S F   +G+ +A E  T+  +  +    G+   DDEG P +   +IE
Sbjct: 266 GHGLEGDFNRRGTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQYNVLIE 325

Query: 309 NGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFG 368
           NGILK  M ++  A    M P G+ R + Y + P+ RM NT   PG  + +E+IE +++G
Sbjct: 326 NGILKGYMQDKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYG 385

Query: 369 YYLVDFRGGQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDF 427
            Y  +F GGQ  + S  F     E Y+I NG++ +P++  ++ G  IE +++IS VG D 
Sbjct: 386 IYAPNFGGGQVDITSGKFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDL 445

Query: 428 AIE--TGFCGK-GQIAFVSSGGPHMRFD 452
            ++   G CGK GQ   V  G P ++ D
Sbjct: 446 KLDNGVGVCGKEGQSLPVGVGQPTLKVD 473


>gb|AAK41402.1| Conserved hypothetical protein [Sulfolobus solfataricus]
           Length = 458
           
 Score =  158 bits (395), Expect = 1e-37
 Identities = 123/454 (27%), Positives = 219/454 (48%), Gaps = 35/454 (7%)

Query: 16  ENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSD----L 71
           +  +  Y+E+R   +    ++  +G         + G ++R   +G   F+S+++    L
Sbjct: 9   DKFRYPYVEVRRHIVSTFGMSFLNGRLMGSFRFTDDGYSVRYYKDGVLYFASSNNPNDLL 68

Query: 72  SKLEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLTEL 131
           S  +E   E ++     +E K+   E+ E KP +             + ++EK+     L
Sbjct: 69  SSNKEYKIEGWESGLDNTEPKEGSYEVKEGKPFD------------LMSVDEKISFFKNL 116

Query: 132 EKLLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARD 191
            + +K+  +VKSV+  Y++   +K ++ N G+RI      L+  + +   +  + A A  
Sbjct: 117 YEAVKDFRSVKSVSFFYDESIEEKEIIVN-GSRIVGRVPRLYVGMNLVLNENNRTATAFY 175

Query: 192 SIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEAL 251
            +G    G E++     NE V D++         G +       VV   ++ G++AHE++
Sbjct: 176 ELGGSG-GLEVLERMNLNEVVVDKVRSVTEVLAKGKSFGERTTDVVLSNMLTGIMAHESV 234

Query: 252 GHLAEADLTMNSPFK--------DLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPVK 302
           GH  EAD  +   F         +L   +I  + VT+  +  +    G    DDEGV  +
Sbjct: 235 GHPFEADRVLGREFAQAGLSYLAELKDNRIGSDVVTVIDDPTIPNSGGYYTTDDEGVEAR 294

Query: 303 DIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMI 362
             ++I++G + E + NR  ++KFN++ NG ARA ++   P+IRM NT F+PG+ +F+E++
Sbjct: 295 PKYLIKDGKVNEYLQNRFSSSKFNVKSNGSARAANFDREPLIRMSNTFFKPGNMTFDELL 354

Query: 363 EDIKFGYYL---VDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKK 419
           ED+K G Y+   +++     +L   + VG+ E Y I+NG+I +P+      G   E LK 
Sbjct: 355 EDVKEGVYIKSYMEWNIDDMRLGQRY-VGL-EAYEIKNGKIGDPVLFPVFQGKTTELLKA 412

Query: 420 ISAVGKDFAIETGFCGKG---QIAFVSSGGPHMR 450
           + AV        G CGKG   Q   V  GGP+MR
Sbjct: 413 VDAVDNTLVFYPGTCGKGDPDQGIPVWLGGPNMR 446


>sp|P57478|TLDD_BUCAI TLDD PROTEIN HOMOLOG >gi|10039067|dbj|BAB13101.1| (AP001119) tldD
           protein [Buchnera sp. APS]
           Length = 483
           
 Score =  153 bits (384), Expect = 3e-36
 Identities = 123/454 (27%), Positives = 209/454 (45%), Gaps = 22/454 (4%)

Query: 21  EYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLS--KLEEAI 78
           +Y +L ++     +  L++ +        + G+ +R +   + GF+ +  +S   L  + 
Sbjct: 34  DYGDLYFQSHIHESWILENSIIKEGNYHSDAGIGVRAIRGESTGFAYSDQISLDSLRRST 93

Query: 79  KEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPRE-VDIEEKVKHLTELEKLLKE 137
           K+A+ +  +    K + +    I+P+         V P E    +EK   L     + + 
Sbjct: 94  KKAHSIILTKGSGKTKTLSKKTIEPIYK------NVNPLEGFSSKEKTDLLYRANYIARS 147

Query: 138 -DETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGA- 195
            D  V  VN        Q ++ + +G  +      +  S+ V  +  GK    R   G+ 
Sbjct: 148 LDHRVIEVNASLTGSYEQILVASTDGNLVSDIRPSIQFSISVLVEDHGKRERGRSGGGSR 207

Query: 196 VDYGWELMTEKEPNEKVKDR----LLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEAL 251
            DY + L  +    E   D      +R     L+      G FPVV G    G++ HEA+
Sbjct: 208 TDYNFFLNQDDSSKEIRIDHWSKEAVRIALLNLSSKEALSGTFPVVLGSGWPGVLLHEAI 267

Query: 252 GHLAEADLTMN--SPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPVKDIHIIE 308
           GH  E D      S F +++GK++A E  T+  +  ++   G+   DDEG P +   +IE
Sbjct: 268 GHGLEGDFNRKGTSIFTNMIGKKVASELCTIIDDGTIKNQRGSLSIDDEGTPGQKNILIE 327

Query: 309 NGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFG 368
           NGILK+ M ++  A    ++  G+ R + Y   P+ RM NT    G    +++I+ + +G
Sbjct: 328 NGILKKYMQDKLNARLMGVKSTGNGRRESYSCLPMPRMTNTYMLSGKSKLDDIIKSVDYG 387

Query: 369 YYLVDFRGGQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDF 427
            Y V+F GGQ  + S  F     E Y+I+NG+I  PI++T++ G  +E ++KIS VG D 
Sbjct: 388 IYAVNFSGGQVDITSGKFVFSTSEAYLIKNGKIVTPIKNTTLIGSGLEVMQKISMVGDDL 447

Query: 428 AIE--TGFCGK-GQIAFVSSGGPHMRFDGGIIIG 458
            ++   G CGK GQ   V  G P M+ +   I G
Sbjct: 448 KMDEGMGICGKDGQNIPVGIGQPSMKLENLTIGG 481


>pir||D72342 tldD protein - Thermotoga maritima (strain MSB8)
           >gi|4981251|gb|AAD35808.1|AE001743_10 (AE001743) tldD
           protein [Thermotoga maritima]
           Length = 499
           
 Score =  153 bits (382), Expect = 5e-36
 Identities = 121/426 (28%), Positives = 190/426 (44%), Gaps = 21/426 (4%)

Query: 21  EYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAIKE 80
           ++ EL +E        LKDG     T     GV IR        ++ T+DLS+ E  I  
Sbjct: 57  DFAELFFERKYENRYELKDGKIEQATSGEIVGVGIRGFLGTKAVYAYTNDLSR-ENLINV 115

Query: 81  AYKLAKSASETKKEKIELAEIKPVEDFVKSKMK------VKPREVDIEEKVKHLTELEKL 134
           A K+ ++  ETK E +         +F ++K K      + P +V+  +KV  + +    
Sbjct: 116 AKKVGEALGETKVEDLTF-------NFNRTKRKERHVVLIPPAQVEKTDKVSVMKKAYYA 168

Query: 135 LKE-DETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSI 193
            K   E +K V + Y D   + ++  +EGT  E         +    +K+G L       
Sbjct: 169 AKNYSELIKQVVVWYWDYDQEILVANSEGTWAEDRRVRTRLMINAVAEKDGVLERGFYGP 228

Query: 194 GAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGH 253
           GA   G+E     +  E  K +  R     +       G+  VV      G+I HEA+GH
Sbjct: 229 GA-GMGFEFFDRIDVEEAAK-KAARIAARMVEAEPAPAGKMTVVIANGFGGVIFHEAVGH 286

Query: 254 LAEADLTMN--SPFKDLLGKQIAPEYVT-MSERYVEGGFGNDKYDDEGVPVKDIHIIENG 310
             EA       S F   LG+++A E V+ + +  +  G+G+   DDEG P +   +I+ G
Sbjct: 287 GLEATSVAKGASVFAGKLGQKVAAECVSAVDDATIPNGWGSANVDDEGTPTQRTLLIDKG 346

Query: 311 ILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYY 370
           +L   ++++    +  M+  G  R QDY +PP  RM NT   PGD+  EE+I   ++G Y
Sbjct: 347 VLVGYLVDKLGERRMGMKSTGSGRRQDYTFPPTSRMSNTFILPGDYHPEEIIAATEYGLY 406

Query: 371 LVDFRGGQAQ-LNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAI 429
                GG        F   + E Y+I  G I +P+R  ++ G   E ++KI  VG D A 
Sbjct: 407 AKTMGGGSVNPATGEFNFAVSEAYLIEKGRITKPVRGATLIGKGHEIIQKIDMVGNDLAR 466

Query: 430 ETGFCG 435
           + G CG
Sbjct: 467 DQGMCG 472


>pir||G82325 tldD protein VC0422 [imported] - Vibrio cholerae (group O1 strain
           N16961) >gi|9654844|gb|AAF93595.1| (AE004129) tldD
           protein [Vibrio cholerae]
           Length = 481
           
 Score =  151 bits (377), Expect = 2e-35
 Identities = 119/444 (26%), Positives = 212/444 (46%), Gaps = 16/444 (3%)

Query: 21  EYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAIKE 80
           +Y ++ ++     +L L+D +    +  ++ GV +R ++    GF+  SD  +LE   + 
Sbjct: 34  DYADIYFQSSWHESLVLEDSIIKDGSFNIDCGVGVRAVSGEKTGFAY-SDQIQLEGLKQS 92

Query: 81  AYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLTELEKLLKEDET 140
           A      A + +   ++  +      F  +   ++  E   ++K + L +L+  ++  E 
Sbjct: 93  AIAARGIAQQGQNLTVQAFKRAQHPAFYGAHNPLESWEK--QQKTELLKQLDAYIRTKEP 150

Query: 141 -VKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGAVDYG 199
            +  V++       Q ++   +GT        +  S+ V  +K G       + G   +G
Sbjct: 151 LITEVSVSLSGVHEQILVAATDGTYAGDIRPLVRLSISVLAQK-GDRRERGSAGGGGRFG 209

Query: 200 WELMTEKEPNEKVK----DRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLA 255
           ++   ++E  +K+     D  +R+    L  VA   G  PVV G    G++ HEA+GH  
Sbjct: 210 YDYFLQEEAGQKIAFSFADEAIRQALVNLEAVAAPAGTMPVVLGSGWPGVLLHEAVGHGL 269

Query: 256 EADLTM--NSPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPVKDIHIIENGIL 312
           E D     +S F   +GK++  +  T+  +  ++   G+   DDEGV  +   +IE GIL
Sbjct: 270 EGDFNRKGSSVFAGKVGKKVTSDLCTIVDDGTLKDLRGSLNVDDEGVSGQYNVLIEKGIL 329

Query: 313 KEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLV 372
           K  + ++  A    + P G+ R + Y + P+ RM NT   PG+ + EE+I  +K G Y  
Sbjct: 330 KGYIQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLPGEHTPEEIIASVKKGIYAP 389

Query: 373 DFRGGQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAIE- 430
           +F GGQ  + S  F     E Y+I NG+I  PI+  ++ G  IEA++++S VG D A++ 
Sbjct: 390 NFGGGQVDITSGKFVFSASEAYLIENGKITRPIKGATLIGSGIEAMQQVSMVGNDLALDR 449

Query: 431 -TGFCGK-GQIAFVSSGGPHMRFD 452
             G CGK GQ   V  G P ++ D
Sbjct: 450 GVGVCGKAGQSVPVGVGQPTLKLD 473


>sp|P74002|YD22_SYNY3 HYPOTHETICAL 53.1 KD PROTEIN SLR1322 >gi|7429840|pir||S75512
           hypothetical protein slr1322 - Synechocystis sp. (strain
           PCC 6803) >gi|1653157|dbj|BAA18073.1| (D90911)
           hypothetical protein [Synechocystis sp.]
           Length = 489
           
 Score =  148 bits (371), Expect = 9e-35
 Identities = 111/448 (24%), Positives = 196/448 (42%), Gaps = 21/448 (4%)

Query: 20  AEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLS--KLEEA 77
           A+++E   E +   +   +D   TS T +L+ G  +RV       + ST+D+S   L  A
Sbjct: 43  ADFVEFFLEKVNYVSCLAEDDAITSLTPRLSSGCGVRVYKGKGDCYVSTNDISFNGLRTA 102

Query: 78  IKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVK--PREVDIEEKVKHLTEL-EKL 134
           +++   +        +  +    ++ + D+  +K K +   R   ++E    L    +KL
Sbjct: 103 LEKGLSILGLTLPAGQSFVPELNLEMLRDYAGAKEKDQWLHRCSPMQEMSDILLGANQKL 162

Query: 135 LKEDETVKSVNIRYEDGGGQKILLTNEGT---RIEWDYNYLWQSVYVTGKKEGKLAMARD 191
                  +S    Y     + ++  ++GT    I    +  +      G+    +     
Sbjct: 163 DHYASHAQSRRAAYFRDWQEVLVAASDGTFARDIRLTQSVGFSLFCADGEHRTSIGKRSG 222

Query: 192 SIGAVDY--GWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHE 249
                DY   W+  T  +   +   ++L   + +        G +P++      G+I HE
Sbjct: 223 DTSNPDYLRTWDAETSAQEVAESAGKMLYADYVE-------SGNYPIIMANQFGGVIFHE 275

Query: 250 ALGHLAEADLTMN--SPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPVKDIHI 306
           A GHL E     +  +PF D  G++IA E +T   E   +  FG    DDEG+P +   +
Sbjct: 276 ACGHLLETTQIEHKTTPFLDKKGEKIAHENLTAWDEGLTDNAFGTIDMDDEGMPTQRTLL 335

Query: 307 IENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIK 366
           IENGILK  + +R  + +      G  R Q Y Y    RMRNT   PG++S +++   ++
Sbjct: 336 IENGILKNFIADRTGSIRTGHPRTGSGRRQSYAYAAASRMRNTYIAPGNYSVDDIFNSVE 395

Query: 367 FGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKD 426
            G Y     GG       F   + E Y++ NG++ +P++  ++ G A E + KIS   +D
Sbjct: 396 KGIYCKQMGGGSVGATGEFNFAVSEAYLVENGKLTKPLKGATLIGTATEIMNKISMSSQD 455

Query: 427 FAIETGFCGK-GQIAFVSSGGPHMRFDG 453
             +  GFCG      +V+ G PH++ DG
Sbjct: 456 LGLAAGFCGSVSGSVYVTVGQPHIKVDG 483


>emb|CAC11942.1| (AL445065) conserved hypothetical protein [Thermoplasma
           acidophilum]
           Length = 455
           
 Score =  145 bits (363), Expect = 8e-34
 Identities = 125/470 (26%), Positives = 210/470 (44%), Gaps = 49/470 (10%)

Query: 7   LEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANG-AWGF 65
           L++ L +A    K+ + + R+ +++     +++G F       + G AIRV+ +  A  +
Sbjct: 2   LDRILDYAGS--KSAFADARFMEIEGRGAVIRNGEFDESLYSNDSGYAIRVVNDSIAMAY 59

Query: 66  SSTSDLSKLEEAIKEAYKLAKSASETK-----KEKIELAEIKPVEDFVKSKMKVKPREVD 120
             + D  K+   + +A   ++   + +      EK   +EI    D V+           
Sbjct: 60  VDSEDWDKVRAVVDDAVLRSRRPGKNRIYRGRSEKASWSEIG--SDHVRDHS-------- 109

Query: 121 IEEKVKHLTELEKLLKE-DETVKSVNIRYE---DGGGQKILLTNEGTRIEWDYNYLWQSV 176
                  L ++  +LKE D   +  N+R     D    ++    +G+ +E  Y+ ++ + 
Sbjct: 110 -------LGDMIAILKEADSVAEEANVRISALSDRFVHQVYENTDGSHVEGTYSRIFFNY 162

Query: 177 YVTGKKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPV 236
            V   +  +   + +  G    G++    K  +E +K+ +   L   +   + + G F V
Sbjct: 163 LVGVSENDRYEQSSEEFGWTG-GYDAFDFKTISETMKNDV-SNLREIILAPSVEPGNFDV 220

Query: 237 VAGPIIVGLIAHEALGHLAEADLTMNSPF-----KDLLGK----QIAPEYVTM-SERYVE 286
           + GP I G++AHE+ GH  E D              L GK    +I  E V++  +  ++
Sbjct: 221 IVGPEISGIVAHESAGHPTEYDRIAGREAALAGESFLTGKTFPYRIGSEKVSVIDDPTLK 280

Query: 287 GGFGNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRM 346
           G +G   YDDEGV  +  ++  NG   E ++NRE AA    E NG  R+  +   P+ RM
Sbjct: 281 GSYGYYLYDDEGVRARKRYLYRNGYTSEFLINRESAAWIGQESNGSGRSSSWDMEPLARM 340

Query: 347 RNTVFEPGDWSFEEMIEDIKFGYYLVDFRG---GQAQLNSAFQVGIQEGYVIRNGEIAEP 403
             T  EPGD+SFEE+ E +  G Y+  F        + N  + VG +E Y I NG+I   
Sbjct: 341 STTYIEPGDYSFEELFEGVHRGIYIKSFTEWNIDDIRFNERY-VG-KEAYYIENGDIKGR 398

Query: 404 IRDTSITGVAIEALKKISAVGKDFAIETGFCGKG---QIAFVSSGGPHMR 450
           +R   +    I+    + AVGKD     G CGKG   Q   V  GGPHMR
Sbjct: 399 VRRPILETNTIKFYSAVDAVGKDLHFSAGICGKGDPEQGVEVWMGGPHMR 448


>pir||F82718 TldD protein XF1127 [imported] - Xylella fastidiosa (strain 9a5c)
           >gi|9106089|gb|AAF83937.1|AE003949_1 (AE003949) TldD
           protein [Xylella fastidiosa]
           Length = 485
           
 Score =  143 bits (357), Expect = 4e-33
 Identities = 113/447 (25%), Positives = 212/447 (47%), Gaps = 20/447 (4%)

Query: 21  EYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAIKE 80
           ++ +L ++  +R + +++DG+    T  + +GV +R ++    GF+ + D+++  +A+ E
Sbjct: 37  DFGDLYFQHARRESWSIEDGIVKDGTHSIEQGVGVRAISGEKTGFAYSDDINR--DALLE 94

Query: 81  AYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPR-----EVDIEEKVKHLTELEKLL 135
           A   A++ S +  + ++      +    + ++ + P       +D  EK+  +  +++LL
Sbjct: 95  AAYAARAISRSPGDGVQGTHAVLLHQ--ERELCLYPALDPVGGMDNAEKIAVMRRVDQLL 152

Query: 136 KE-DETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIG 194
           +  D  V  V +    G    ++  ++G         +  +V V  +  G+        G
Sbjct: 153 RAADPRVTQVMVNLSGGVDVVLIARSDGVLAADVRPLVRLNVQVIVEGHGRRESGYAG-G 211

Query: 195 AVDYGW-ELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGH 253
              YG+ EL  +  P    ++ L + L + L  +    G  PVV G    G++ HEA+GH
Sbjct: 212 GGRYGYAELFADGRPEAFAREALRQALVN-LEAIPAPAGVMPVVLGAGWPGVLLHEAVGH 270

Query: 254 LAEADLTMN--SPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPVKDIHIIENG 310
             E D      S +   +G+++A   VT+  +  ++G  G+   DDEG P +   +IE+G
Sbjct: 271 GLEGDFNRKGTSVYAGRIGERVASPGVTIVDDGTLDGRRGSLNIDDEGTPTQCTTLIEDG 330

Query: 311 ILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYY 370
           +L   M +   A    +   G+ R + + +  + RM NT    G  S EEMI  +K G Y
Sbjct: 331 VLVGYMQDTLNARLMGVASTGNGRRESFAHLTMPRMTNTYMRAGVHSREEMIRSVKKGLY 390

Query: 371 LVDFRGGQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAI 429
            V+F GGQ  + S  +     E Y+I +G +  PI+  ++ G   E ++++  +G D A+
Sbjct: 391 AVNFGGGQVDITSGKYVFSATEAYLIEDGRVTAPIKGATLIGNGPETMQRVRMIGDDLAL 450

Query: 430 E--TGFCGK-GQIAFVSSGGPHMRFDG 453
           +   G CGK GQ   V  G P +  DG
Sbjct: 451 DAGVGVCGKDGQSVPVGVGQPSLLIDG 477


>sp|P45297|TLDD_HAEIN TLDD PROTEIN HOMOLOG
           Length = 482
           
 Score =  141 bits (353), Expect = 1e-32
 Identities = 119/456 (26%), Positives = 210/456 (45%), Gaps = 38/456 (8%)

Query: 21  EYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFS-----STSDLSKLE 75
           +Y +L ++  +  +  L+DG+    +  ++RGV +R ++    GF+     + + L +  
Sbjct: 33  DYADLYFQLSQDESWVLEDGIIKEGSFHIDRGVGVRAVSGEKTGFAYADQINLASLQQCA 92

Query: 76  EAIK------EAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLT 129
           EA+K      +   ++ SA          A I P+E   K            E+K++ L 
Sbjct: 93  EAVKGIAQVKQGNLISPSAFNVVNPIARYAAINPLESLTK------------EKKIELLH 140

Query: 130 ELEKLLK-EDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAM 188
            +++  + ED  V  V+        + +++  +GT        +  S+ V  ++ GK   
Sbjct: 141 LVDRTARAEDHRVTKVSASLSSVYEEVLIMATDGTLAADIRPLVRLSISVLVEENGK--R 198

Query: 189 ARDSIGA-----VDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIV 243
            R S G+     +D+ +E++             +R+    L+ VA   G  PVV G    
Sbjct: 199 ERGSCGSGGRFGLDWFFEVVDGDIRAVLFAKEAVRQALVNLSAVAAPAGLMPVVLGAGWP 258

Query: 244 GLIAHEALGHLAEADLTM--NSPFKDLLGKQI-APEYVTMSERYVEGGFGNDKYDDEGVP 300
           G++ HEA+GH  E D     +S F   +G+Q+ +P    + +  +E   G+   DDEGVP
Sbjct: 259 GVLLHEAVGHGLEGDFNRKESSLFTGKIGEQVTSPLCTIVDDGTIENRRGSLTIDDEGVP 318

Query: 301 VKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEE 360
            +   +I++GIL+  M ++  A    +   G+ R + Y + P+ RM NT    G   F++
Sbjct: 319 SQCNVLIKDGILQGYMQDKMNARLMGVSTTGNGRRESYAHLPMPRMTNTYMLAGQSQFDD 378

Query: 361 MIEDIKFGYYLVDFRGGQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKK 419
           +I  +K G Y   F GGQ  + S  F     E Y+I  G+I +P++  ++ G  IE ++K
Sbjct: 379 LIASVKQGIYAPHFGGGQVDITSGKFVFSTSEAYLIEKGKITKPVKGATLIGSGIEVMQK 438

Query: 420 ISAVG--KDFAIETGFCGK-GQIAFVSSGGPHMRFD 452
           IS V    +  +  G CGK GQ   V  G P ++ D
Sbjct: 439 ISMVADKSELDLGIGVCGKEGQSVPVGVGQPALKID 474


>pir||D83086 conserved hypothetical protein PA4474 [imported] - Pseudomonas
           aeruginosa (strain PAO1)
           >gi|9950711|gb|AAG07862.1|AE004861_3 (AE004861)
           conserved hypothetical protein [Pseudomonas aeruginosa]
           Length = 480
           
 Score =  139 bits (346), Expect = 8e-32
 Identities = 112/441 (25%), Positives = 205/441 (46%), Gaps = 20/441 (4%)

Query: 24  ELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAIKEAYK 83
           +L ++     +  L+DG+    +  L++GV +R  +    GF+ ++ ++   EA+K+A  
Sbjct: 39  DLYFQSQVSESWMLEDGIVKEGSFNLDQGVGVRAQSGEKTGFAYSNAITA--EALKQAAV 96

Query: 84  LAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDI---EEKVKHLTELEKLLKE-DE 139
            A+S S   +       ++  +  V +++      +D+    EKV+ L +++   +  D 
Sbjct: 97  AARSISRAGQN----GSVQAFKAVVPARLYAGENPLDVLSRAEKVELLKQIDAATRALDP 152

Query: 140 TVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMA-RDSIGAVDY 198
            ++ V +       Q ++  ++G+        +  +V V  ++ G+         G  DY
Sbjct: 153 RIQQVTVSMAGVWEQILVAASDGSLAADIRPLVRFNVSVIVEQNGRRERGGHGGGGRTDY 212

Query: 199 GWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAEAD 258
            + L  ++          LR+    L  +    G  PVV G    G++ HEA+GH  E D
Sbjct: 213 RYFLQEDRAMG--YAREALRQALVNLEAIPAPAGTLPVVMGAGWSGVLLHEAVGHGLEGD 270

Query: 259 LTM--NSPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPVKDIHIIENGILKEI 315
                +S +   +G+++A    T+  +  + G  G+   DDEG P     +IENG+LK  
Sbjct: 271 FNRKGSSAYSGRVGEKVASSLCTIVDDGTLAGRRGSLSVDDEGTPSNCNVLIENGVLKGY 330

Query: 316 MLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFR 375
           M ++  A    +   G+ R + Y + P+ RM NT    G+   +E+I  ++ G Y  +  
Sbjct: 331 MQDKLNARLMGVARTGNGRRESYAHLPMPRMTNTYMLAGESDPQEIIASVEKGIYCANLG 390

Query: 376 GGQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAIETGF- 433
           GGQ  + S  F     E Y+I NG I  P++  ++ G   EA+ ++S VG D A+++G  
Sbjct: 391 GGQVDITSGKFVFSTSEAYLIENGRITTPVKGATLIGNGPEAMSRVSMVGNDLALDSGVG 450

Query: 434 -CGK-GQIAFVSSGGPHMRFD 452
            CGK GQ   V  G P ++ D
Sbjct: 451 TCGKDGQSVPVGVGQPTLKID 471


>gb|AAC43985.2| (U33883) TldD [Bradyrhizobium japonicum]
           Length = 479
           
 Score =  133 bits (331), Expect = 4e-30
 Identities = 117/435 (26%), Positives = 188/435 (42%), Gaps = 15/435 (3%)

Query: 24  ELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAIKEAYK 83
           EL  E  +   L   +G     T   ++G  +R + + A G++ +SD+S     +    +
Sbjct: 39  ELFLEYSQTEALMFDNGRLKQATYDTSQGFGLRAVKDDAVGYAHSSDVS-----LPALIR 93

Query: 84  LAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVD-IEEKVKHLTELEKLLKE-DETV 141
            A + +  +          P    V+      P +    E KVK L E++  L++ D  V
Sbjct: 94  AADAVAAVRGGYSGSFSAPPPHTNVRLYGDDNPLDAPGFETKVKLLAEIDAYLRDKDPRV 153

Query: 142 KSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGAVDYGWE 201
           + V++          +L  +G         +  ++ V   +  +        G    G+ 
Sbjct: 154 RQVSVTLGATWQVVEILRPDGESYRDIRPLVRVNISVVAGQGDRQESGSKGYGG-RAGYA 212

Query: 202 LMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAEADLTM 261
              E +      D  LR+    L  +    GE  VV G    G++ HEA+GH  E D   
Sbjct: 213 EFIESKNWRDAADGALREALVNLESIPAPAGEMDVVLGAGWPGVMLHEAVGHGLEGDFNR 272

Query: 262 N--SPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPVKDIHIIENGILKEIMLN 318
              S F  L+G+Q+A + VT+  +  +    G+   DDEG P     +IE+GIL   M +
Sbjct: 273 KRTSAFAGLMGRQVAAKGVTVVDDGTIASRRGSLSIDDEGTPTNRTVLIEDGILVGYMQD 332

Query: 319 REYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFRGGQ 378
           R+ A   NM+P G+ R Q Y + P+ RM NT    GD    E++  +K G +  +F GGQ
Sbjct: 333 RQNARLMNMKPTGNGRRQGYAHVPMPRMTNTYMLAGDRDPAEILASVKNGVFAANFGGGQ 392

Query: 379 AQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAIETGF--CG 435
             + S  +     E Y I NG+I  P++   + G     L +I  +G D A++TG   CG
Sbjct: 393 VDITSGKYVFQCTEAYKIENGKIGAPLKGAMLIGNGPTDLHRIRMIGNDLALDTGIGTCG 452

Query: 436 K-GQIAFVSSGGPHM 449
           K GQ   V  G P +
Sbjct: 453 KNGQGVPVGVGQPSL 467


>pir||G70473 tldD homolog - Aquifex aeolicus >gi|2984257|gb|AAC07784.1|
           (AE000768) TldD protein [Aquifex aeolicus]
           Length = 404
           
 Score =  127 bits (317), Expect = 2e-28
 Identities = 109/399 (27%), Positives = 184/399 (45%), Gaps = 24/399 (6%)

Query: 21  EYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGA--WGFSSTSDLSKLEEAI 78
           EY E+ YE  + T + L+D      T   + GV +R++ NG   +G+++      L+E  
Sbjct: 19  EYGEIFYEKSRTTRMHLEDRKIDKVTHGYDEGVGLRLIKNGKTYYGYTTNPTFENLKE-- 76

Query: 79  KEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLTEL-EKLLKE 137
                LAK  +  +         + ++ +  +++ + P +  ++ + + L    EK    
Sbjct: 77  -----LAKILARGEGHGPVAIGKRYIQGY--TEVLIDPDKESLKFRAEILRRADEKARSF 129

Query: 138 DETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGAVD 197
            + +K V     D   + +++   G   E     +   V V       L    +S+G   
Sbjct: 130 GDKIKQVLAVLMDKTREIMVINTLGETAEDTQKRVVFFVEVVASDGETLQRGYESLGG-R 188

Query: 198 YGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAEA 257
            G+E+  E  P E + ++  ++    L+      G F VV      G + HEA+GH  EA
Sbjct: 189 RGFEIFNETPP-EVIAEKAAKRALLMLSAKPAPAGTFTVVMSSQAGGTMIHEAVGHGLEA 247

Query: 258 DLTMN--SPFKDLLGKQIAPEYVTMSER----YVEGGFGNDKYDDEGVPVKDIHIIENGI 311
           DL     S +   LG+++A E VT+ +     Y  G F     DDEGVP +   +I++G+
Sbjct: 248 DLVQQGLSVYAGKLGEKVASELVTVIDDATLPYHNGSF---TVDDEGVPAQRKVLIKDGV 304

Query: 312 LKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYL 371
           L   M +R  A K  +E  G+ R Q Y + PI+RM NT  + G  + E++I+D K G  +
Sbjct: 305 LVGYMYDRLRAMKDGVESTGNGRRQSYAHIPIVRMTNTFIDKGQDNPEDIIKDTKKGVLV 364

Query: 372 VDFRGGQAQ-LNSAFQVGIQEGYVIRNGEIAEPIRDTSI 409
           V   GG+   +   F   + EGY+I NGEI  PIR  ++
Sbjct: 365 VKMGGGEVNTVTGDFVFEVMEGYMIENGEITYPIRGATL 403


>pir||A82033 TLDD protein homolog NMA0367 [imported] - Neisseria meningitidis
           (group A strain Z2491) >gi|7379119|emb|CAB83668.1|
           (AL162752) TLDD protein homolog [Neisseria meningitidis
           Z2491]
           Length = 480
           
 Score =  125 bits (310), Expect = 1e-27
 Identities = 113/448 (25%), Positives = 192/448 (42%), Gaps = 49/448 (10%)

Query: 37  LKDGVFTSFTEKLNRGVAIRVLANG--AWGFSSTSDLSKLEEAIKEAYKLAKSASETKKE 94
           L++G+  S + ++N+GV +R ++    A+ ++ +  +  +  + +    +  +  +   +
Sbjct: 52  LEEGIVKSGSFQINQGVGVRAVSGDKTAFAYADSLCIDSINRSARAVRAIGAAGGKVSAK 111

Query: 95  KIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQ 154
                  KPV              +D   KV  L ++E + K  +               
Sbjct: 112 MPSETRGKPV-----CSASDPIAGLDSAAKVALLNKVEAIAKAADP-------------- 152

Query: 155 KILLTNEGTRIEWDYNYLWQSVYVTGK-----------------KEGKLAMARDSIGAVD 197
           +I+    G   E+D  YL +   + GK                 K+G+      + G   
Sbjct: 153 RIVQVMAGLTCEYDMVYLAR---LDGKHAADIRPMVRLNVTVIAKQGERREQGSAGGGGR 209

Query: 198 YGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAEA 257
           Y      E    + V D  +++  + L       GE  VV G    G++ HEA+GH  E 
Sbjct: 210 YDLAYFDENLVRQFV-DAAVKQALTNLESRPAPAGEMTVVLGNGWPGVLLHEAVGHGLEG 268

Query: 258 DLTMN--SPFKDLLGKQIAPEYVTMSERY-VEGGFGNDKYDDEGVPVKDIHIIENGILKE 314
           D      S F   +G+++A + VT+ ++  + G  G+   DDEG   +   +IE+GIL  
Sbjct: 269 DFNRKGTSVFSGRIGERVAAKGVTVVDQGDIAGRRGSLNIDDEGNETRRTVLIEDGILVG 328

Query: 315 IMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDF 374
            M +   A     +  G+ R + Y   P+ RM NT  E G +  EE+I  I  G Y V+F
Sbjct: 329 YMQDETNARLTGTQSTGNGRRESYASAPMPRMTNTFMENGSYEPEEIIASIDKGIYAVNF 388

Query: 375 RGGQAQLNSA-FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAIET-- 431
            GGQ  + S  F     E + +  G +  P++  +I G   E LK +S +G D A+++  
Sbjct: 389 GGGQVDITSGKFVFSASEAWWVEGGRLQYPVKGATIIGNGPEVLKHVSMIGNDTALDSGV 448

Query: 432 GFCGK-GQIAFVSSGGPHMRFDGGIIIG 458
           G CGK GQ   V  G P +R D G+ +G
Sbjct: 449 GVCGKEGQSVPVGVGQPTLRIDAGLTVG 476


>pir||F81010 tldD protein NMB2066 [imported] - Neisseria meningitidis  (group B
           strain MD58) >gi|7227328|gb|AAF42385.1| (AE002556) tldD
           protein [Neisseria meningitidis MC58]
           Length = 480
           
 Score =  124 bits (309), Expect = 2e-27
 Identities = 82/252 (32%), Positives = 125/252 (49%), Gaps = 7/252 (2%)

Query: 214 DRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAEADLTMN--SPFKDLLGK 271
           D  +++  + L       GE  VV G    G++ HEA+GH  E D      S F   +G+
Sbjct: 225 DAAVKQALTNLESRPAPAGEMTVVLGNGWPGVLLHEAVGHGLEGDFNRKGTSVFSGRIGE 284

Query: 272 QIAPEYVTMSERY-VEGGFGNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPN 330
           ++A + VT+ ++  + G  G+   DDEG   +   +IE+GIL   M +   A     +  
Sbjct: 285 RVAAKGVTVVDQGDIAGRRGSLNIDDEGNETRRTVLIEDGILVGYMQDETNARLTGTQST 344

Query: 331 GHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFRGGQAQLNSA-FQVGI 389
           G+ R + Y   P+ RM NT  E G +  EE+I  I  G Y V+F GGQ  + S  F    
Sbjct: 345 GNGRRESYASAPMPRMTNTFMENGSYEPEEIIASIDKGIYAVNFGGGQVDITSGKFVFSA 404

Query: 390 QEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAIET--GFCGK-GQIAFVSSGG 446
            E + +  G +  P++  +I G   E LK +S +G D A+++  G CGK GQ   V  G 
Sbjct: 405 SEAWWVEGGRLQYPVKGATIIGNGPEVLKHVSMIGNDTALDSGVGVCGKEGQSVPVGVGQ 464

Query: 447 PHMRFDGGIIIG 458
           P +R D G+ +G
Sbjct: 465 PTLRIDAGLTVG 476


>pir||E72342 pmbA-related protein - Thermotoga maritima (strain MSB8)
           >gi|4981252|gb|AAD35809.1|AE001743_11 (AE001743)
           pmbA-related protein [Thermotoga maritima]
           Length = 435
           
 Score =  117 bits (291), Expect = 2e-25
 Identities = 109/418 (26%), Positives = 191/418 (45%), Gaps = 33/418 (7%)

Query: 23  IELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAIKEAY 82
           +++ + + +  +L L +G    +T+     V I+VL +G  G   T  L   E+  +EA 
Sbjct: 21  VQISFLETREFSLRLANGDLDQYTDAGKFNVEIKVLKDGKTGTFRTQVLENPEKCFEEAL 80

Query: 83  K-LAKSASETKKEKIELA-EIKPVEDFVKSKMKVKPREVDIEEKVKHLTELEKLLKEDET 140
             L    SE K+   E   E + +E +V    K+  +E     K  H    E   K++  
Sbjct: 81  SNLQVKDSEEKEYFFEGGKEYREMETYVGRFEKLSVKEKMDMAKKAH----ESAAKDERV 136

Query: 141 VKSVNIRYEDGGGQKILLTNEGTRIE--WDYNYLWQSVYVTGKKEGKLAMARDSIGAVDY 198
           V    + Y+D   +KI+    G  +E   D  +L+            +A+ARD+      
Sbjct: 137 VMVPTVMYKDMVIKKIITNTLGLDVESQMDGGFLFA-----------MAIARDANPRSGS 185

Query: 199 GWELMTEKEP--NEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAE 256
            +EL    E    E++  R   +  S +       G++PV+     +  +    +  ++ 
Sbjct: 186 WYELARTPEDLNPEEIGKRAAEEAISLIGSKTIPSGKYPVLMRNTALLDLMEMFIPMISA 245

Query: 257 ADLTMN-SPFKDLLGKQIAPEYVTMSER-YVEGGFGNDKYDDEGVPVKDIHIIENGILKE 314
            ++  N SP K  LG+Q+    V++ +  Y   G  +  +DDEGVP  +  ++ENG+LK 
Sbjct: 246 ENVQKNLSPLKGKLGEQVGNPAVSIKDLPYHPKGLSSTPFDDEGVPTTEKFVLENGVLKT 305

Query: 315 IMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDF 374
            + N + A K  +EP G+       +   IR  N +  PG+ SFEE+++++  G  + + 
Sbjct: 306 FLHNLKTARKEGVEPTGNG------FVGGIRPVNLMLMPGEKSFEELLKEMDRGVVITEV 359

Query: 375 RGGQAQLNS---AFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAI 429
            G  A  NS    F +   +GY + NGEIA  + D +I+G  ++ L+KI  VG D  +
Sbjct: 360 EGMHAGANSISGEFSL-FAKGYWVENGEIAHGVEDITISGNFLDLLRKIVLVGNDVKV 416


>dbj|BAB05755.1| (AP001514) suppressor of the inhibitory activity of the cabon
           storage regulator (CsrA) [Bacillus halodurans]
           Length = 432
           
 Score =  112 bits (278), Expect = 7e-24
 Identities = 76/228 (33%), Positives = 113/228 (49%), Gaps = 13/228 (5%)

Query: 232 GEFPVVAGPIIVGLIAHEALGHLAEADLTM--NSPFKDLLGKQIAPEYVTMSERYVEGGF 289
           G + ++ GP+    I HE +GH  EAD+     S F   LG  +  E VT+ +   + G 
Sbjct: 198 GSYALILGPLAAPGIFHEVVGHGLEADIASIPQSAFHQRLGAMVGCEKVTIIDDPTKEGL 257

Query: 290 -GNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRN 348
            G+   DDEG   +   +IE G +   + +           NGH R  +Y++ P++RM N
Sbjct: 258 PGSYSLDDEGTIAQQTTLIEKGRVVNYLSHLHTGHP----TNGHGRVINYQHLPLVRMSN 313

Query: 349 TVFEPGDWSFEEMIEDIKFGYYLVDFRGGQAQL-NSAFQVGIQEGYVIRNGEIAEPIRDT 407
           T   PG    EEM+ D + G Y+     G   +    F++ + EGY+I  G+I  PI  T
Sbjct: 314 TFLLPGTDDPEEMVSDTEVGLYVKKAINGDVNMITGEFEIHVAEGYLIEKGQITSPILPT 373

Query: 408 SITGVAIEALKKISAVGKDFAIET---GFCGK-GQIAF-VSSGGPHMR 450
           ++ G   + L+ I  VG DFAI +   G CGK GQ    VS+G P +R
Sbjct: 374 TLKGDGQKLLQSIDRVGNDFAIHSEVRGGCGKLGQSPLPVSAGSPTVR 421


>pir||S70839 tldD homolog - Bradyrhizobium japonicum (fragment)
           Length = 313
           
 Score =  107 bits (265), Expect = 2e-22
 Identities = 80/241 (33%), Positives = 114/241 (47%), Gaps = 8/241 (3%)

Query: 217 LRKLHSQLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAEADLTMN--SPFKDLLGKQIA 274
           LR+    L  +    GE  VV G    G++ HEA+GH  E D      S F  L+G+Q+A
Sbjct: 61  LREALVNLESIPAPAGEMDVVLGAGWPGVMLHEAVGHGLEGDFNRKRTSAFSGLMGRQVA 120

Query: 275 PEYVTM-SERYVEGGFGNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHA 333
            + VT+  +  +    G+   DDEG P     +IE+GIL   M +R+ A   NM+P G+A
Sbjct: 121 AKGVTVVDDGTIASRRGSLSIDDEGTPTNRTVLIEDGILVGYMQDRQNARLMNMKPTGNA 180

Query: 334 RAQDYRYPPIIRMRNTVFEPG-DWSFEEMIEDIKFGYYLVDFRGGQAQLNSAFQVG-IQE 391
            A+ Y + P+ RM NT    G   S   ++  +K      +F GGQ  + S   V    E
Sbjct: 181 AARRYAHVPMPRMTNTYMLRGRSRSGRGVLASVKNAASRANFGGGQVDITSGKYVSQCTE 240

Query: 392 GYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAIETGF--CGK-GQIAFVSSGGPH 448
            Y   NG+   P     + G     L +I  +G D A++TG   CGK GQ   V  G P 
Sbjct: 241 AYKSENGKSGGPAEGRMLIGNGPTDLHRIRMIGNDLALDTGIGTCGKNGQGVPVGVGQPS 300

Query: 449 M 449
           +
Sbjct: 301 L 301


>pir||D70703 tldD homolog Rv2315c - Mycobacterium tuberculosis (strain H37RV)
           >gi|1524285|emb|CAB02052.1| (Z79702) hypothetical
           protein Rv2315c [Mycobacterium tuberculosis]
           Length = 505
           
 Score = 98.7 bits (242), Expect = 1e-19
 Identities = 115/479 (24%), Positives = 187/479 (39%), Gaps = 32/479 (6%)

Query: 5   ESLEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWG 64
           + L  A   A     A + +LR   +    + L+DG   +       G+A+RV+  G WG
Sbjct: 17  QQLADAALSAAATAGASHADLRVHRISTEIIQLRDGELETAVISRELGLAVRVIVAGTWG 76

Query: 65  FSSTSDLSK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVK--SKMKVKPREVD 120
           F+S ++L+        + A  +A   +    E++ LA  +PV    +  S  ++ P  V 
Sbjct: 77  FASHAELAPDVAAATARHAVHVATVLAALNTERVRLAP-EPVYTDAEWVSNYRIDPFGVP 135

Query: 121 IEEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQ--SVYV 178
             EK+  L +    L + + +  V+        Q       G+ I      L        
Sbjct: 136 ASEKIAVLRDYSGRLLDADGIDHVSASLNAVKEQTFYADTFGSSITQQRVRLLPCLDAVA 195

Query: 179 TGKKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKD--RLLRKLHSQLNGVAPKRGEFPV 236
                G     R        GWE++   E      +  +L   L  ++   +   G   +
Sbjct: 196 VDSAAGNFESMRTLAPPTARGWEVVAGDEIWNWTDELAQLPSLLAEKVRAPSVMPGPTDL 255

Query: 237 VAGPIIVGLIAHEALGHLAEADLTM---------NSPFKDLLG--KQIAPEYVTMSERYV 285
           V  P  + L  HE++GH  E D  +         +    D LG  +  +P     ++R  
Sbjct: 256 VIDPTNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGTLRYGSPVMNVTADRTA 315

Query: 286 EGGFGNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEP--NGHARAQDYRYPPI 343
           E G     YDDEGV  +   ++ +G+     L+R +A +   EP  NG + A    + PI
Sbjct: 316 EFGLATVGYDDEGVAAQSWDLVRDGVFVGYQLDRAFAPRLG-EPRSNGCSYADSPHHVPI 374

Query: 344 IRMRNTVFEPG--DWSFEEMIEDIKFGYYLVDFRGGQAQLNS-AFQVGIQEGYVIRNGEI 400
            RM N   +PG  D S  ++I  +  G Y+V  +     +    FQ   Q  + IR G++
Sbjct: 375 QRMANISLQPGIEDLSTADLIGRVDDGIYIVGDKSWSIDMQRYNFQFTGQRFFRIRGGQL 434

Query: 401 AEPIRDTSITGVAIEALKKISAVGKDFAIETG---FCGK---GQIAFVSSGGPHMRFDG 453
              +RD +      +    + AVG       G    CGK   GQ+A VS G P   F G
Sbjct: 435 YGQLRDVAYQSSTTDFWNAMEAVGGPSTWRMGGAINCGKAQPGQVAAVSHGCPSALFRG 493


>gb|AAD53904.1|AF176314_14 (AF176314) PmbA [Zymomonas mobilis]
           Length = 448
           
 Score = 91.3 bits (223), Expect = 2e-17
 Identities = 95/358 (26%), Positives = 163/358 (44%), Gaps = 28/358 (7%)

Query: 67  STSDLSK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEK 124
           S+SD SK  L+  ++ A  +A+ A E +      A + P E  ++        E D  ++
Sbjct: 70  SSSDFSKEALDALVERAVAMAREAPEDR-----WAGLAPKELLMQGT--APEIESDDGKE 122

Query: 125 VKHLTELEKLLKEDETVKSVN-IRYEDGG----GQKI--LLTNEG-TRIEWDYNYLWQSV 176
           +      E  LK ++  +SV+ I   +G     G+ I  L T+EG TR     +Y   + 
Sbjct: 123 IAPAVLRELALKAEDAARSVDGITNSEGASASAGRTIFALATSEGFTRGSSSSSYGCSAC 182

Query: 177 YVTGKKEGKLAMARD-SIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFP 235
            + G+    + M RD    A  Y  +L    +  E +  R   +  ++LN      G+ P
Sbjct: 183 VIAGQG---VNMQRDYDFHATRYFEDL----DAAELIGTRAAERTIARLNPTRIDSGQMP 235

Query: 236 VVAGPII-VGLIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSER-YVEGGFGNDK 293
           ++  P +  G +++   G    A     S   D LGK +  E +T+ E  + + G  +  
Sbjct: 236 IIFDPRVGSGFLSYLIQGISGGAITRKTSFLLDSLGKPVFNEGITIKEDPWRKRGIASRA 295

Query: 294 YDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEP 353
           +D EG+P K  +II+ G L   +L+   A +  M P GHAR +    PP     N   E 
Sbjct: 296 FDGEGLPTKPNNIIDKGRLNGWLLDSAAARQLGMTPTGHAR-RGVGGPPSTGTANLYLEA 354

Query: 354 GDWSFEEMIEDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITG 411
           G  + EE++ DIK G Y+ +  G    + +        G++IR+G++AEP+ + ++ G
Sbjct: 355 GKVTPEELMSDIKLGIYVTEMIGSGVNMITGDYSRGASGFIIRDGQLAEPVAEITVAG 412


>pir||F71033 hypothetical protein PH1558 - Pyrococcus horikoshii
           >gi|3257987|dbj|BAA30670.1| (AP000006) 445aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 445
           
 Score = 90.9 bits (222), Expect = 3e-17
 Identities = 104/432 (24%), Positives = 188/432 (43%), Gaps = 22/432 (5%)

Query: 4   MESLEKALKWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAW 63
           M  +E+ +K+ E     + +E+     +   L ++    +  T +++    +R + +   
Sbjct: 1   MRKMEELIKYGERFF--DELEIVTYRAREIGLEVELNEISMGTTRMSTITIVRGIKDNRI 58

Query: 64  GFSSTSDLSK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDI 121
           G S   + SK  +++AI+EA K+A+  +   K K  L E  P +   K K+  + +E   
Sbjct: 59  GISIVDNDSKEDVKKAIEEAAKMARLNNPDDKWK-SLPE--PGKYREKPKVNEELKEAST 115

Query: 122 EEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQKILLTNE-GTRIEWDYNYLWQSVYVTG 180
           E     + +  +L +E +   +V          +  + N  G  +  +Y +        G
Sbjct: 116 ETLASMVIKGIQLARESDPNVTVAGGSAGASWSEFSIANSHGVNVTQEYGHAHVFFEFVG 175

Query: 181 KKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGP 240
           KKEG   +    I   D    L  + E    + +R + ++         K  E PV+  P
Sbjct: 176 KKEG---VVTPGIFEFDIKDNLNLDVE---SIVNRGIERVKWAYKVKEAKNEEAPVIFSP 229

Query: 241 IIVGLIAHEAL--GHLAEADLTMNSPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDE 297
             +  + H AL      E  +   +P  D +G++IA + +T+  + + E        D E
Sbjct: 230 WAISGLFHYALFPAFSGERLIKKTTPLADKVGEKIASDVITIYDDTFHELSVVKAIADGE 289

Query: 298 GVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPI-IRMRNTVFEPGDW 356
           GVP +   +IENG+ K  + +  +A  +  E  GH + +D+R   + I + + V E G  
Sbjct: 290 GVPTRKTMLIENGVFKGFIWDNYWAKVYGTESTGHGQ-RDWRGGGVTIGLNSAVIENGKR 348

Query: 357 SFEEMIEDIKFGYYLVDFRGGQAQL--NSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAI 414
           S EEMI+DIK GY +   +G  +    N  F +     Y+I +GEIA        + +  
Sbjct: 349 SLEEMIQDIKHGYLVEGVQGAHSSNPDNGNFAISANPAYLIEDGEIAGSTVFLVASNI-Y 407

Query: 415 EALKKISAVGKD 426
           E LK+ S V K+
Sbjct: 408 ELLKQASEVSKE 419


>pir||D82066 pmbA protein VC2535 [imported] - Vibrio cholerae (group O1 strain
           N16961) >gi|9657118|gb|AAF95676.1| (AE004322) pmbA
           protein [Vibrio cholerae]
           Length = 447
           
 Score = 88.9 bits (217), Expect = 1e-16
 Identities = 65/213 (30%), Positives = 106/213 (49%), Gaps = 16/213 (7%)

Query: 222 SQLNGVAPKRGEFPVV-AGPIIVGLIAHEALGHLAEADLTMNSPFK-DLLGKQIAPEYVT 279
           S+L+    K G+FPV+ A  +  GLI H  +  ++  +L   S F  D LGK I P +  
Sbjct: 229 SRLDPQKLKTGQFPVMFAADVATGLIGHLVMA-ISGGNLYRKSSFLLDHLGKTILPTWFN 287

Query: 280 MSER-YVEGGFGNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDY 338
           +SER +V  G  +  +D EGV  +D+ II +G+L   +L    A K NM P GHA     
Sbjct: 288 ISERPHVMRGLASSPFDSEGVRTQDLEIITDGVLATYLLTSYAARKMNMTPTGHAGG--- 344

Query: 339 RYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNG 398
                  + N   +    ++++M++++  G  + +  G    + +        G+ + NG
Sbjct: 345 -------IHNWYVKSTGQNYQQMLKELGTGLLVTEVMGQGVNVVTGDYSRGAAGFWVENG 397

Query: 399 EIAEPIRDTSITGVAIEALKKISAVGKDFAIET 431
           EI  P+ + +I G   + L++I AVG D  IET
Sbjct: 398 EIKYPVSEITIAGNLKQMLQQIVAVGSD--IET 428


>pir||B75213 pmba protein (tlde protein) PAB0155 - Pyrococcus abyssi  (strain
           Orsay) >gi|5457662|emb|CAB49153.1| (AJ248283) PMBA
           PROTEIN (TLDE PROTEIN) [Pyrococcus abyssi]
           Length = 427
           
 Score = 86.6 bits (211), Expect = 5e-16
 Identities = 98/396 (24%), Positives = 169/396 (41%), Gaps = 39/396 (9%)

Query: 48  KLNRGVAIRVLANGAWGFSSTSDLS----KLEEAIKEAYKLAKSASETKKEKIELAEIKP 103
           +++ G+ +RVL  G  GFS  S  +    +LE  +K AYK+AK A           +   
Sbjct: 49  EVSGGIGLRVLTQGKIGFSYISGSNFTREQLERLVKRAYKIAKVAGSIYPGFPVPKKFPN 108

Query: 104 VEDFVKSKMKVKPREVDIEEKVKHLTELEKLLKEDETVKSVNIRYEDGGGQKILLTNEGT 163
           V      K+    R +  EE V++ TEL  +    E   S+ +   + G    ++ + GT
Sbjct: 109 VRGLYDDKI----RNLSTEEIVEYGTELVDVPPNAEA--SIGLSTSERG----IMNSNGT 158

Query: 164 RIEWDYNYLWQSVYVTGKKEGKLAMARDSIGAVDYGWELMTEKEPN-EKVKDRLLRKLHS 222
               +   L   +YV  K +G         G+    +  + + E   E V+++ L +   
Sbjct: 159 EGREERTLLAFGLYVFEKSKGT--------GSYSKSFRRLPKLESEIEGVREKALWEFEM 210

Query: 223 QLNGVAPKRGEFPVVAGPIIVGLIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTM-S 281
                  ++    ++  P  V  I    L +++  ++ +       LG ++A   +T+  
Sbjct: 211 SSKARKLEKYNGEIILEPKAVASILSIFLPNVSARNVYLKRSRFTELGIEVASGGLTIID 270

Query: 282 ERYVEGGFGNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYP 341
           +  VEGG  +  +D EG P     II+ GIL   + +++Y     +   G+A ++ Y   
Sbjct: 271 DPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNA-SRGYSSQ 329

Query: 342 PIIRMRNTVFEPGDWSFEEMIEDIKF-GYYLVDFRGGQAQLNSA---FQVGIQEGYVIRN 397
           P I   N +  PG+   +E  E I   G Y      G+   NS    F + +  GYV+R 
Sbjct: 330 PSISPSNIMISPGN---DEQDEGIFIRGIY------GEHTANSVSGDFSLNVDLGYVVRG 380

Query: 398 GEIAEPIRDTSITGVAIEALKKISAVGKDFAIETGF 433
           GEI  P +   + G   E LK ++ +GK+  I  GF
Sbjct: 381 GEI-RPFKGNMLVGNVFEMLKNVTNIGKEIEILDGF 415


>pir||B75180 antibiotic/peptide maturation related protein PAB1956 - Pyrococcus
           abyssi (strain Orsay) >gi|5458031|emb|CAB49521.1|
           (AJ248284) ANTIBIOTIC/PEPTIDE MATURATION related protein
           [Pyrococcus abyssi]
           Length = 448
           
 Score = 83.9 bits (204), Expect = 3e-15
 Identities = 93/368 (25%), Positives = 163/368 (44%), Gaps = 22/368 (5%)

Query: 68  TSDLSKLEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKH 127
           T    ++++AI+EA K+AK  +  +K     +  K  E   K K+    + V  E  V+ 
Sbjct: 68  TDSKEEVKKAIEEAAKMAKLNTPDEKWSSLPSPGKYRE---KPKVSEDLKSVSTETLVEF 124

Query: 128 LTELEKLLKEDETVKSVNIRYEDGG---GQKILLTNEGTRIEWDYNYLWQSVYVTGKKEG 184
           +T   KL +E +   +V +     G    +  +  ++G  +  ++          GKKEG
Sbjct: 125 VTRGIKLARESDP--NVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKKEG 182

Query: 185 KLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGP-IIV 243
            +       G  D+  +   E +  E V +R L ++    N    K  E  V+ GP  I 
Sbjct: 183 VVTP-----GIFDFDAKDNLELDV-EGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAIS 236

Query: 244 GLIAHEALGHLA-EADLTMNSPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPV 301
           GL+++      + E  +   +P  D +G+++A + +T+  + + E        D EGVP 
Sbjct: 237 GLLSYALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPT 296

Query: 302 KDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPI-IRMRNTVFEPGDWSFEE 360
           + + +IE GI K  + +  +A  +  E  GH + +D+R   + I + + V E G     E
Sbjct: 297 RKVTLIEEGIFKGFIWDNYWAKVYGTESTGHGQ-RDWRGGGVSIGLNSAVIENGKRELSE 355

Query: 361 MIEDIKFGYYLVDFRGGQAQL--NSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALK 418
           +I +IK GY +   +G  +    N  F V     Y+I +GE+        I G   E LK
Sbjct: 356 IIGEIKHGYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVVGS-TVFLIAGNVYELLK 414

Query: 419 KISAVGKD 426
           + + V KD
Sbjct: 415 QATEVSKD 422


>pir||B83330 hypothetical protein PA2529 [imported] - Pseudomonas aeruginosa
           (strain PAO1) >gi|9948585|gb|AAG05917.1|AE004680_5
           (AE004680) hypothetical protein [Pseudomonas aeruginosa]
           Length = 477
           
 Score = 83.1 bits (202), Expect = 6e-15
 Identities = 99/453 (21%), Positives = 187/453 (40%), Gaps = 35/453 (7%)

Query: 12  KWAEENIKAEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDL 71
           ++A    +AE+  LRY       L+++  V        +RG  + V  NG   +++T+DL
Sbjct: 8   RFAALRSRAEFHSLRYVQRSGEYLSVRRNVSEPPHFSQDRGAMLCVRLNGVEAYAATNDL 67

Query: 72  SK--LEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLT 129
           S   L+ A+++A        E + E+I    +  V     +  + + R  + +     L 
Sbjct: 68  SAAGLQAALEQA--------ERQAERIARHALFDVRGLPPASGRSQYRSPNQDAPFPSLA 119

Query: 130 ELEKLLKE-------DETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKK 182
           E  +LL E       DE + + ++  E    +++ L + G     +  +++    VT   
Sbjct: 120 ECYELLAEESAKVPRDERLVNWSVFLEVSRQEQLYLNSAGAEQYHEQRFVYPGASVTAY- 178

Query: 183 EGKLAMARDSIG--AVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGP 240
           +G  +  R   G  A   G   + E+        R+  +    L       G   ++  P
Sbjct: 179 DGHDSQTRSFGGHHAGQQGGAEVIERLGLVGAAPRIADQALQLLAAPNTPSGRCDLLLMP 238

Query: 241 IIVGLIAHEALGHLAEADLTMNSP----------FKDLLGKQIAPEYVTMS-ERYVEGGF 289
             + L  HE++GH  E D  +              +D    Q     + +S +  +    
Sbjct: 239 DQMILQIHESIGHPLELDRILGDERNYAGTSFIKTEDFGRYQYGSSLLNVSFDPEIPEEL 298

Query: 290 GNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNT 349
            + + DD+G P +  ++I  G L   +       +  +E   ++RA  +   PI RM N 
Sbjct: 299 ASYRQDDDGSPARKEYLIREGRLLRPLGGALSQHRSGLEGVANSRASSWNRAPIDRMANL 358

Query: 350 VFEPGDWSFEEMIEDIKFGYYLVDFRGGQAQ-LNSAFQVGIQEGYVIRNGEIAEPIRDTS 408
             EPGD SF +++  I+ G  +   R        + FQ G + G +I +GE+   +++ +
Sbjct: 359 NLEPGDKSFAQLVAGIERGVLMSYNRSWSIDDARNKFQFGCEWGQLIEDGELKGVVKNPN 418

Query: 409 ITGVAIEALKKISAVGKDFAIE---TGFCGKGQ 438
             G++ +  + +SAVG     E   T +CGKG+
Sbjct: 419 YRGISAQFWRNLSAVGDAGTFEVLGTPYCGKGE 451


>pir||T36780 hypothetical protein SCI28.10 - Streptomyces coelicolor  (fragment)
           >gi|5525068|emb|CAB50884.1| (AL096844) hypothetical
           protein [Streptomyces coelicolor A3(2)]
           Length = 435
           
 Score = 82.7 bits (201), Expect = 8e-15
 Identities = 101/406 (24%), Positives = 165/406 (39%), Gaps = 28/406 (6%)

Query: 20  AEYIELRYEDLKRTTLTLKDGVFTSFTEKLNRGVAIRVLANGAWGFSSTSDLSKLEEAIK 79
           AE+ + R E ++  +  L+D      ++  + G A+RV+  G WGF+S  DL+ L+ A K
Sbjct: 30  AEHADFRLERVRNASWRLRDARPAGSSDTTDLGYAVRVVHGGTWGFASGVDLT-LDAAAK 88

Query: 80  ---EAYKLAKSASETKK-----EKIEL-AEIKPVEDFVKSKMKVKPREVDIEEKVKHLTE 130
              +A  +AK +++  K     E++EL AE    +    S  ++ P  V   +K   L +
Sbjct: 89  VASQAVAMAKLSAQVIKAAGSDERVELAAEPVHADKSWISAYEIDPFSVPDADKAALLAD 148

Query: 131 LEKLLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQ--SVYVTGKKEGKLAM 188
               L   + V  V+         K      GT        L    +        G+   
Sbjct: 149 WSARLLAADGVDHVDASLLTVHENKFYADTAGTVTTQQRVRLHPVLTAVSVDDSSGEFDS 208

Query: 189 ARDSIGAVDYGWELMTEKEPN-EKVKDRLLRKLHSQLNGVAPKRGEFPVVAGPIIVGLIA 247
            R        GWE +T    + +     +   L  ++   + + G + +V  P  + L  
Sbjct: 209 MRTLAPPAGRGWEYLTGTGWDWDSELAEIPELLAEKMRAPSVEAGLYDLVVDPSNLWLTI 268

Query: 248 HEALGHLAEADLTMNSPFK---------DLLGK-QIAPEYVTMS-ERYVEGGFGNDKYDD 296
           HE++GH  E D  +              D LGK +   E + ++ +R  E G     YDD
Sbjct: 269 HESIGHATELDRALGYEAAYAGTSFATFDQLGKLRYGSELMNVTGDRTAEHGLATVGYDD 328

Query: 297 EGVPVKDIHIIENGILKEIMLNREYAAKFNME-PNGHARAQDYRYPPIIRMRNTVF--EP 353
           EGV  +   ++++G L    L+R  A     E  NG A A    + P+ RM N     +P
Sbjct: 329 EGVEGQSWDLVKDGTLVGYQLDRRIARLTGFERSNGCAYADSPAHVPVQRMANVSLLPDP 388

Query: 354 GDWSFEEMIEDIKFGYYLVDFRGGQAQLNS-AFQVGIQEGYVIRNG 398
           G  S E++I  +  G Y+V  R     +    FQ   Q  + I NG
Sbjct: 389 GGLSTEDLIGGVDRGIYVVGDRSWSIDMQRYNFQFTGQRFFRIENG 434


>pir||E71135 hypothetical protein PH0849 - Pyrococcus horikoshii
           >gi|3257260|dbj|BAA29943.1| (AP000003) 443aa long
           hypothetical protein [Pyrococcus horikoshii]
           Length = 443
           
 Score = 80.4 bits (195), Expect = 4e-14
 Identities = 58/200 (29%), Positives = 102/200 (51%), Gaps = 12/200 (6%)

Query: 232 GEFPVVAGPI-IVGLIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSE-RYVEGGF 289
           G F V+  P+    L+++      A A     S F + L +++A E VT+ +   +  G+
Sbjct: 221 GRFDVIFDPLAFANLLSYMGWAFSAFAVEAGFSYFANKLDQKVASEIVTIKDVGNLPNGY 280

Query: 290 GNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNT 349
              K+DDEGVP K+  +I  GILK  + N   A K+  E   +A        P  R  N 
Sbjct: 281 ATRKFDDEGVPTKETILIHKGILKTYLFNTSLAKKYGRETTANAGL----IAP--RAWNI 334

Query: 350 VFEPGDWSFEEMIEDIKFGYYLVD--FRGGQAQLNSAFQVGIQEG-YVIRNGEIAEPIRD 406
           V EPGD++ +E+ +++K G Y+ +  +   Q  +   F    ++G ++I NGE+ +PIR+
Sbjct: 335 VLEPGDYTKDELFQEVKKGIYITNVWYTRFQNYMTGDFSTIPRDGIFLIENGEL-KPIRN 393

Query: 407 TSITGVAIEALKKISAVGKD 426
             ++   +  L+ + A+ K+
Sbjct: 394 IRVSDNMLRILQNVVALSKE 413


>pir||F75033 hypothetical protein PAB1548 - Pyrococcus abyssi (strain Orsay)
           >gi|5458676|emb|CAB50163.1| (AJ248287) hypothetical
           protein [Pyrococcus abyssi]
           Length = 443
           
 Score = 80.0 bits (194), Expect = 5e-14
 Identities = 57/200 (28%), Positives = 102/200 (50%), Gaps = 12/200 (6%)

Query: 232 GEFPVVAGPI-IVGLIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSE-RYVEGGF 289
           G+F V+  P+    L+++      A A     S F + L +++A E VT+ +   +  G+
Sbjct: 221 GKFDVIFDPLAFANLLSYMGWAFSAFAVEAGFSYFANKLDQKVASEVVTIKDIGNLPNGY 280

Query: 290 GNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNT 349
           G  K+DDEGVP ++  +IE G LK  + N   A K+  E   +A           R  N 
Sbjct: 281 GTRKFDDEGVPTRETVLIERGTLKTYLFNTSLAKKYGKETTANAGLIS------PRAWNI 334

Query: 350 VFEPGDWSFEEMIEDIKFGYYLVD--FRGGQAQLNSAFQVGIQEG-YVIRNGEIAEPIRD 406
           V EPGD++ +E+ +++K G Y+ +  +   Q  +   F    ++G ++I NGE+ +PIR+
Sbjct: 335 VLEPGDYTKDELFQEVKRGIYITNVWYTRFQNYMTGDFSTIPRDGIFLIENGEL-KPIRN 393

Query: 407 TSITGVAIEALKKISAVGKD 426
             ++   +  L+ I  + K+
Sbjct: 394 IRVSDNMLRILQNIVGLTKE 413


>pir||S77207 hypothetical protein slr1435 - Synechocystis sp. (strain PCC 6803)
           >gi|1652621|dbj|BAA17541.1| (D90907) PmbA protein
           [Synechocystis sp.]
           Length = 427
           
 Score = 79.6 bits (193), Expect = 7e-14
 Identities = 56/222 (25%), Positives = 107/222 (47%), Gaps = 14/222 (6%)

Query: 210 EKVKDRLLR-KLHSQLNGVAPKRGEFPVV----AGPIIVGLIAHEALGHLAEADLTMNSP 264
           E ++ RLL  +++ Q+ G     G+ P++    A  ++   +     G     D   +SP
Sbjct: 194 ENLRQRLLWVEVNQQIQG-----GKMPILLTSGAASLLWDTVGEALHGQRVAED---SSP 245

Query: 265 FKDLLGKQIAPEYVTMSERYVEGGFGNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAK 324
           + + LG+ +A E + +S+      F +  +DDEG   + + +I+NG + +   + E A K
Sbjct: 246 WAEKLGQTVAIEELNISQDPTAIPF-DCPFDDEGSRTQKLALIKNGKIAQFYTDHETAEK 304

Query: 325 FNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFRGGQAQLNSA 384
                 G+         P   + N +  PG  SF+++++ +  G  +    GG A ++  
Sbjct: 305 LGTTTTGNGFRPSLGSAPQPGLVNMLITPGTASFDQLLKKLGNGLVVDQILGGGADISGD 364

Query: 385 FQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKD 426
           F + +  GY ++NGEI   ++DT ++G   E L +I A+G D
Sbjct: 365 FSINVDLGYRVQNGEITGRVKDTMVSGNIYELLNQIIALGSD 406


>sp|P45077|PMBA_HAEIN PMBA PROTEIN HOMOLOG >gi|1075002|pir||C64186 pmbA protein -
           Haemophilus influenzae (strain Rd KW20)
           >gi|1574709|gb|AAC22807.1| (U32795) pmbA protein (pmbA)
           [Haemophilus influenzae Rd]
           Length = 451
           
 Score = 78.8 bits (191), Expect = 1e-13
 Identities = 91/383 (23%), Positives = 160/383 (41%), Gaps = 34/383 (8%)

Query: 64  GFSSTSDLSKLEEAIKEAYKLAKS-ASETKKEKIELAEIKPVEDFVKSKMKV-KPREVDI 121
           G +STSDLS  E AIK A + A + A  T  +       K +  F    +++    ++D+
Sbjct: 77  GNASTSDLS--ESAIKNAVEAALAIAKYTSPDDCTGLADKDLMAFDAPDLELYHAADIDV 134

Query: 122 EEKVKHLTELEK--LLKEDETVKSVNIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVT 179
           ++  +   + E+  L  ++  + S    +    G K+   + G    +  +    S  V 
Sbjct: 135 DKATELALQAEQAALQADERIINSNGASFNSHTGVKVYGNSHGMLQSYLSSRYSLSCSVI 194

Query: 180 GKKEGKLAMARDSIGAVDYGWELMTEKEPNEK---VKDRLLRKLHSQLNGVAPKRGEFPV 236
           G  E  L          DY + +  E +  +    V +   +K+ S+LN       E PV
Sbjct: 195 GGVEDALEN--------DYEYTISREFDKLQSPIWVGENCAKKVVSRLNPQKLSTREVPV 246

Query: 237 V-AGPIIVGLIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVTMSER-YVEGGFGNDKY 294
           +    +  G+I+H A      +    +S   D LGKQ+ P++ ++SER ++     +  +
Sbjct: 247 IFLNDVATGIISHFAAAISGGSLYRKSSFLLDHLGKQVLPDWFSISERPHLLRRLASTPF 306

Query: 295 DDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPG 354
           D EGV  +D  I+ENGIL+  ++      K  M   GHA            + N + +P 
Sbjct: 307 DSEGVRTQDREIVENGILQTYLVTSYSGKKLGMSSTGHAGG----------IHNWLVKPN 356

Query: 355 -DWSFEEMIEDIKFGYYLVDFRGGQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVA 413
                  ++  +  G  + D  G    + +        G+ + NGEI  P+ + +I G  
Sbjct: 357 LTGGLTALLRQMGTGLLVTDVMGQGVNIVTGDYSRGASGFWVENGEIQYPVAEITIAGQL 416

Query: 414 IEALKKISAVGKDFA----IETG 432
            + LK + AV  D      I+TG
Sbjct: 417 QDMLKNMLAVADDIEHRSNIQTG 439


>sp|P24231|PMBA_ECOLI PMBA PROTEIN (TLDE PROTEIN) >gi|96308|pir||S13730 pmbA protein -
           Escherichia coli >gi|42440|emb|CAA38091.1| (X54152) pmbA
           is involved in the  production of antibiotic MccB17
           [Escherichia coli] >gi|537077|gb|AAA97132.1| (U14003)
           pmbA gene product [Escherichia coli]
           >gi|1732440|dbj|BAA07915.1| (D44452) TldE protein
           [Escherichia coli] >gi|1790682|gb|AAC77192.1| (AE000494)
           maturation of antibiotic MccB17, see tld genes
           [Escherichia coli K12]
           Length = 450
           
 Score = 74.5 bits (180), Expect = 2e-12
 Identities = 66/247 (26%), Positives = 114/247 (45%), Gaps = 20/247 (8%)

Query: 197 DYGWEL---MTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVV-AGPIIVGLIAHEALG 252
           DY + +   M++ +  E V     R+  S+L+       + PV+ A  +  GL  H  +G
Sbjct: 204 DYAYTIGRAMSDLQTPEWVGADCARRTLSRLSPRKLSTMKAPVIFANEVATGLFGH-LVG 262

Query: 253 HLAEADLTMNSPFK-DLLGKQIAPEYVTMSER-YVEGGFGNDKYDDEGVPVKDIHIIENG 310
            +A   +   S F  D LGKQI P+++T+ E  ++  G  +  +D EGV  +   II++G
Sbjct: 263 AIAGGSVYRKSTFLLDSLGKQILPDWLTIEEHPHLLKGLASTPFDSEGVRTERRDIIKDG 322

Query: 311 ILKEIMLNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYY 370
           IL + +L    A K  ++  GHA            + N        SFE+M++++  G  
Sbjct: 323 ILTQWLLTSYSARKLGLKSTGHAGG----------IHNWRIAGQGLSFEQMLKEMGTGLV 372

Query: 371 LVDFRG-GQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKDFAI 429
           + +  G G + +   +  G   G+ + NGEI  P+ + +I G   +  + I  VG D   
Sbjct: 373 VTELMGQGVSAITGDYSRG-AAGFWVENGEIQYPVSEITIAGNLKDMWRNIVTVGNDIET 431

Query: 430 ETGF-CG 435
            +   CG
Sbjct: 432 RSNIQCG 438


>pir||B83086 PmbA protein PA4472 [imported] - Pseudomonas aeruginosa  (strain
           PAO1) >gi|9950709|gb|AAG07860.1|AE004861_1 (AE004861)
           PmbA protein [Pseudomonas aeruginosa]
           Length = 449
           
 Score = 70.2 bits (169), Expect = 4e-11
 Identities = 95/410 (23%), Positives = 170/410 (41%), Gaps = 39/410 (9%)

Query: 35  LTLKDGVFTSF------TEKLNR--GVAIRVLANGAWGFSSTSDLSK--LEEAIKEAYKL 84
           ++L+ G+ TS       T + NR  G  I + A    G +STS   +  + E +  A  +
Sbjct: 39  VSLEQGLSTSVRQGEVETVEFNRDQGFGITLYAGQRKGSASTSATGEAAIRETVAAALAI 98

Query: 85  AKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKHLTELEKLLKEDETVKSV 144
           A+  SE   E   LA+   +   +       P  +  E+ V      E+ L  +    + 
Sbjct: 99  ARHTSED--ECAGLADAALMARELPELDLYHPWSLSPEQAV------ERALACEAAAFAA 150

Query: 145 NIRYEDGGGQKILLTNEGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGAV--DYGWEL 202
           + R     G   L T++G R+ +  ++ +   Y + +      M  +  G +  DY +++
Sbjct: 151 DKRVTKADGTT-LNTHQGCRV-YGNSHGFIGGYASTRHSLSCVMIAEGEGQMQRDYWYDV 208

Query: 203 MTEKEP---NEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGP-IIVGLIAHEALGHLAEAD 258
               E     E +  R   +  S+L     +  E PV+  P I VGL  H  LG ++   
Sbjct: 209 NRRGEALASAESIGRRAAERAASRLGARPVQTAEVPVLFAPEIAVGLFGH-FLGAISGGS 267

Query: 259 LTMNSPFKD-LLGKQIAPEYVTMSER-YVEGGFGNDKYDDEGVPVKDIHIIENGILKEIM 316
           L   S F +  LG+++ PE++++ ER ++ G  G+  +D +G+       +ENG L   +
Sbjct: 268 LYRKSSFLEGALGQRLFPEWLSIDERPHLVGALGSASFDSDGLATYAKPFVENGELVSYV 327

Query: 317 LNREYAAKFNMEPNGHARAQDYRYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFRG 376
           L      K  +    +A            + N     GD     +I  ++ G  + +  G
Sbjct: 328 LGTYSGRKLGLPSTANAGG----------VHNLFVSHGDEDQAALIRRMERGLLVTELMG 377

Query: 377 GQAQLNSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKISAVGKD 426
               L +        GY + NGEI  P+++ +I     +  ++I AVGKD
Sbjct: 378 QGVNLVTGDYSRGAAGYWVENGEIQFPVQEVTIAANLRDLFRRIVAVGKD 427


>pir||B69009 conserved hypothetical protein MTH1070 - Methanobacterium
           thermoautotrophicum (strain Delta H)
           >gi|2622168|gb|AAB85559.1| (AE000877) conserved protein
           [Methanobacterium thermoautotrophicum]
           Length = 430
           
 Score = 69.1 bits (166), Expect = 1e-10
 Identities = 88/386 (22%), Positives = 159/386 (40%), Gaps = 43/386 (11%)

Query: 52  GVAIRVLANGAWGFSSTSDLSKLEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSK 111
           G+ IR+L  G  GF+ TSD   ++ A++ A            + ++LA+  P E+F  S+
Sbjct: 48  GIGIRILKEGRMGFAYTSDPDGVDVAVRMA-----------AQNLQLAD--PDENFGFSE 94

Query: 112 MKVKPREVDIEEKVKHLTELEKLLKEDETVKSVNIRYEDG-----GG------QKILLTN 160
               P    I ++     E+E  +  +   + +N   E+G     GG      +  +L +
Sbjct: 95  PSTYPSVKGIHDRSFDDLEVEDSV--EMAGRMINRVLEEGCKPTSGGFTASRIETFILNS 152

Query: 161 EGTRIEWDYNYLWQSVYVTGKKEGKLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKL 220
           EG             + VT  + G    A +S    D   +L    E    V  R  R  
Sbjct: 153 EGVEESSSSTGFSAHISVTAGENGMKTTAYES----DSSCKLDINPE---WVAGRACRIA 205

Query: 221 HSQLNGVAPKRGEFPVVAG-PIIVGLIAHEALGHLAEADLTMNSPFKDLLGKQIAPEYVT 279
              + G + + G  P V       GL+   A    A+      S   D +G Q+  E ++
Sbjct: 206 RDSMGGRSIESGRIPAVLDYHAAAGLLGTFAGAFSADNVQRGRSVLADRIGSQVTGEGLS 265

Query: 280 M-SERYVEGGFGNDKYDDEGVPVKDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDY 338
           +  +  +EGG G+  +D EG P +   ++E+GIL+  M N   A+K   +  G+   + Y
Sbjct: 266 VYDDGTLEGGLGSAPFDGEGTPSQRTALVEDGILRGYMHNIYTASKGRADSTGNG-LRGY 324

Query: 339 RYPPIIRMRNTVFEPGDWSFEEMIEDIKFGYYLVDFRGGQA--QLNSAFQVGIQEGYVIR 396
              P +   N + E   +     ++D + G ++ D  G      ++  F V     ++  
Sbjct: 325 MEVPAVSTTNFILE---FDSTVPLDDFR-GIFVTDVLGAHTANPISGDFSVEANNAFMAD 380

Query: 397 NGEIAEPIRDTSITGVAIEALKKISA 422
           +GE   P++   ++G   E + K+S+
Sbjct: 381 SGEFT-PVKKAMLSGNIFELMMKVSS 405


  Database: ./suso.pep
    Posted date:  Jul 6, 2001  5:57 PM
  Number of letters in database: 840,471
  Number of sequences in database:  2977
  
  Database: /banques/blast2/nr.pep
    Posted date:  Dec 14, 2000 12:46 PM
  Number of letters in database: 188,266,275
  Number of sequences in database:  595,510
  
Lambda     K      H
   0.315    0.136    0.388 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 174263123
Number of Sequences: 2977
Number of extensions: 7730745
Number of successful extensions: 24565
Number of sequences better than 1.0e-10: 46
Number of HSP's better than  0.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 24418
Number of HSP's gapped (non-prelim): 51
length of query: 458
length of database: 189,106,746
effective HSP length: 58
effective length of query: 400
effective length of database: 154,394,500
effective search space: 61757800000
effective search space used: 61757800000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 42 (22.0 bits)
S2: 166 (69.1 bits)