BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1956 (pmbA-like) DE:ANTIBIOTIC/PEPTIDE MATURATION related
protein
(448 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||B75180 antibiotic/peptide maturation related protein PAB195... 894 0.0
pir||F71033 hypothetical protein PH1558 - Pyrococcus horikoshii ... 746 0.0
sp|Q57684|Y231_METJA HYPOTHETICAL PROTEIN MJ0231 >gi|2128001|pir... 158 1e-37
pir||B69009 conserved hypothetical protein MTH1070 - Methanobact... 143 3e-33
pir||E70461 pmbA protein - Aquifex aeolicus >gi|2984159|gb|AAC07... 138 1e-31
gb|AAD53904.1|AF176314_14 (AF176314) PmbA [Zymomonas mobilis] 120 3e-26
pir||B75213 pmba protein (tlde protein) PAB0155 - Pyrococcus aby... 120 4e-26
gb|AAK40966.1| Zn-dependent protease, tldE protein homolog, puta... 117 2e-25
emb|CAB57641.1| (Y18930) hypothetical protein [Sulfolobus solfat... 117 2e-25
pir||B71249 hypothetical protein PH0249 - Pyrococcus horikoshii ... 113 5e-24
pir||E72342 pmbA-related protein - Thermotoga maritima (strain M... 106 4e-22
pir||S77207 hypothetical protein slr1435 - Synechocystis sp. (st... 106 7e-22
pir||F75033 hypothetical protein PAB1548 - Pyrococcus abyssi (st... 106 7e-22
gi|11498264 antibiotic maturation protein (pmbA) [Archaeoglobus ... 104 2e-21
pir||E71135 hypothetical protein PH0849 - Pyrococcus horikoshii ... 99 9e-20
pir||D64424 tldD homolog MJ0996 - Methanococcus jannaschii 91 2e-17
sp|Q58403|Y996_METJA HYPOTHETICAL PROTEIN MJ0996 >gi|2826357|gb|... 90 3e-17
pir||G71248 tldD homolog PH0246 - Pyrococcus horikoshii >gi|3256... 90 4e-17
pir||F81010 tldD protein NMB2066 [imported] - Neisseria meningit... 90 6e-17
sp|P46473|TLDD_ECOLI TLDD PROTEIN >gi|7429829|pir||F65116 tldD p... 89 1e-16
pir||A82033 TLDD protein homolog NMA0367 [imported] - Neisseria ... 88 2e-16
sp|P57478|TLDD_BUCAI TLDD PROTEIN HOMOLOG >gi|10039067|dbj|BAB13... 88 2e-16
pir||G70473 tldD homolog - Aquifex aeolicus >gi|2984257|gb|AAC07... 87 3e-16
sp|P45297|TLDD_HAEIN TLDD PROTEIN HOMOLOG 85 1e-15
pir||D72342 tldD protein - Thermotoga maritima (strain MSB8) >gi... 85 1e-15
sp|P45077|PMBA_HAEIN PMBA PROTEIN HOMOLOG >gi|1075002|pir||C6418... 84 3e-15
pir||C75180 tldd related protein PAB1955 - Pyrococcus abyssi (st... 84 3e-15
pir||S75708 hypothetical protein sll0887 - Synechocystis sp. (st... 81 3e-14
gb|AAC43985.2| (U33883) TldD [Bradyrhizobium japonicum] 81 3e-14
sp|P74002|YD22_SYNY3 HYPOTHETICAL 53.1 KD PROTEIN SLR1322 >gi|74... 80 5e-14
pir||F82718 TldD protein XF1127 [imported] - Xylella fastidiosa ... 80 7e-14
pir||G82325 tldD protein VC0422 [imported] - Vibrio cholerae (gr... 78 2e-13
sp|P24231|PMBA_ECOLI PMBA PROTEIN (TLDE PROTEIN) >gi|96308|pir||... 77 3e-13
pir||E71033 tldD-related protein PH1557 - Pyrococcus horikoshii ... 77 4e-13
pir||A75213 tldd protein PAB0154 - Pyrococcus abyssi (strain Ors... 77 4e-13
emb|CAC11943.1| (AL445065) conserved hypothetical protein [Therm... 76 6e-13
pir||D83086 conserved hypothetical protein PA4474 [imported] - P... 75 1e-12
pir||B82719 PmbA protein XF1131 [imported] - Xylella fastidiosa ... 72 1e-11
pir||D82066 pmbA protein VC2535 [imported] - Vibrio cholerae (gr... 71 2e-11
>pir||B75180 antibiotic/peptide maturation related protein PAB1956 - Pyrococcus
abyssi (strain Orsay) >gi|5458031|emb|CAB49521.1|
(AJ248284) ANTIBIOTIC/PEPTIDE MATURATION related protein
[Pyrococcus abyssi]
Length = 448
Score = 894 bits (2285), Expect = 0.0
Identities = 448/448 (100%), Positives = 448/448 (100%)
Query: 1 MDEVGEMEELIKYGEKFFDELEIVVRRSRGIEVNVELNEISMGATRIEKVTIIRGIKDKR 60
MDEVGEMEELIKYGEKFFDELEIVVRRSRGIEVNVELNEISMGATRIEKVTIIRGIKDKR
Sbjct: 1 MDEVGEMEELIKYGEKFFDELEIVVRRSRGIEVNVELNEISMGATRIEKVTIIRGIKDKR 60
Query: 61 VGIAIIDTDSKEEVKKAIEEAAKMAKLNTPDEKWSSLPSPGKYREKPKVSEDLKSVSTET 120
VGIAIIDTDSKEEVKKAIEEAAKMAKLNTPDEKWSSLPSPGKYREKPKVSEDLKSVSTET
Sbjct: 61 VGIAIIDTDSKEEVKKAIEEAAKMAKLNTPDEKWSSLPSPGKYREKPKVSEDLKSVSTET 120
Query: 121 LVEFVTRGIKLARESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKK 180
LVEFVTRGIKLARESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKK
Sbjct: 121 LVEFVTRGIKLARESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKK 180
Query: 181 EGVVTPGIFDFDAKDNLELDVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAISGLLS 240
EGVVTPGIFDFDAKDNLELDVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAISGLLS
Sbjct: 181 EGVVTPGIFDFDAKDNLELDVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAISGLLS 240
Query: 241 YALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVT 300
YALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVT
Sbjct: 241 YALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVT 300
Query: 301 LIEEGIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEIIGEI 360
LIEEGIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEIIGEI
Sbjct: 301 LIEEGIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEIIGEI 360
Query: 361 KHGYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVVGSTVFLIAGNVYELLKQATEVS 420
KHGYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVVGSTVFLIAGNVYELLKQATEVS
Sbjct: 361 KHGYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVVGSTVFLIAGNVYELLKQATEVS 420
Query: 421 KDQRALPFMTTAITPYIKFENVKIAGKK 448
KDQRALPFMTTAITPYIKFENVKIAGKK
Sbjct: 421 KDQRALPFMTTAITPYIKFENVKIAGKK 448
>pir||F71033 hypothetical protein PH1558 - Pyrococcus horikoshii
>gi|3257987|dbj|BAA30670.1| (AP000006) 445aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 445
Score = 746 bits (1904), Expect = 0.0
Identities = 352/443 (79%), Positives = 396/443 (88%)
Query: 6 EMEELIKYGEKFFDELEIVVRRSRGIEVNVELNEISMGATRIEKVTIIRGIKDKRVGIAI 65
+MEELIKYGE+FFDELEIV R+R I + VELNEISMG TR+ +TI+RGIKD R+GI+I
Sbjct: 3 KMEELIKYGERFFDELEIVTYRAREIGLEVELNEISMGTTRMSTITIVRGIKDNRIGISI 62
Query: 66 IDTDSKEEVKKAIEEAAKMAKLNTPDEKWSSLPSPGKYREKPKVSEDLKSVSTETLVEFV 125
+D DSKE+VKKAIEEAAKMA+LN PD+KW SLP PGKYREKPKV+E+LK STETL V
Sbjct: 63 VDNDSKEDVKKAIEEAAKMARLNNPDDKWKSLPEPGKYREKPKVNEELKEASTETLASMV 122
Query: 126 TRGIKLARESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKKEGVVT 185
+GI+LARESDPNVTVAGGSAG SW+E I NS G+NV+QE+G AH+FFEFVGKKEGVVT
Sbjct: 123 IKGIQLARESDPNVTVAGGSAGASWSEFSIANSHGVNVTQEYGHAHVFFEFVGKKEGVVT 182
Query: 186 PGIFDFDAKDNLELDVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAISGLLSYALFP 245
PGIF+FD KDNL LDVE +VNRG+ERVKWAY VKEAKNEE VIF PWAISGL YALFP
Sbjct: 183 PGIFEFDIKDNLNLDVESIVNRGIERVKWAYKVKEAKNEEAPVIFSPWAISGLFHYALFP 242
Query: 246 AFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVTLIEEG 305
AFSGERL+KKTTPLADKVGEK+ASDVITIYDDTFHELS+ KAIADGEGVPTRK LIE G
Sbjct: 243 AFSGERLIKKTTPLADKVGEKIASDVITIYDDTFHELSVVKAIADGEGVPTRKTMLIENG 302
Query: 306 IFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEIIGEIKHGYL 365
+FKGFIWDNYWAKVYGTESTGHGQRDWRGGGV+IGLNSAVIENGKR L E+I +IKHGYL
Sbjct: 303 VFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVTIGLNSAVIENGKRSLEEMIQDIKHGYL 362
Query: 366 VEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVVGSTVFLIAGNVYELLKQATEVSKDQRA 425
VEG+QGAHSSNPDNGNFA++ANPAYLIEDGE+ GSTVFL+A N+YELLKQA+EVSK+QRA
Sbjct: 363 VEGVQGAHSSNPDNGNFAISANPAYLIEDGEIAGSTVFLVASNIYELLKQASEVSKEQRA 422
Query: 426 LPFMTTAITPYIKFENVKIAGKK 448
+P M T + PYIKFENV+IAGK+
Sbjct: 423 MPAMFTVVAPYIKFENVRIAGKR 445
>sp|Q57684|Y231_METJA HYPOTHETICAL PROTEIN MJ0231 >gi|2128001|pir||H64328 hypothetical
protein MJ0231 - Methanococcus jannaschii
>gi|1590966|gb|AAB98219.1| (U67479) pmbA protein (pmbA)
[Methanococcus jannaschii]
Length = 416
Score = 158 bits (396), Expect = 1e-37
Identities = 116/416 (27%), Positives = 202/416 (47%), Gaps = 31/416 (7%)
Query: 6 EMEELIKYGEKFFDELEIVVRRSRGIEVNVELNEISMGATRIEKVTIIRGIKDKRVGIAI 65
++E+LIK GEK E E++ +S + V+++ + T I +R IKD +VG A
Sbjct: 2 DLEKLIKIGEKEGFETEVLFVKSYEVSVDLDGKSVDSFQTGISYGIGVRVIKDGKVGFAY 61
Query: 66 IDTDSKEEVKKAIEEAAKMAKLNTPDEKWSSLPSPGKYRE-KPKVSEDLKSVSTETLVE- 123
+ + V KA++ N ++K++ P KY+E K +++ + E L+E
Sbjct: 62 ANKFDENIVYKAMK--------NLVEDKYTEFAHPQKYKEPKGMFYKEILDLDEEKLLED 113
Query: 124 -FVTRGIKLARESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQE--FGSAHIFFEFVGKK 180
R I L D N V G + NS G++V ++ + SA I + G+
Sbjct: 114 LITMRDIAL----DNNAIVLSGGVSKEVGYARLINSNGVDVEEQDTYFSAAISIMYDGET 169
Query: 181 EGVVTPGIFDFDAKDNLELDVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAISGLLS 240
++ + N+ DVE + R L+ K + N K A + + ++ P A+ LLS
Sbjct: 170 S-------YECRTRHNI-FDVEEISYRALDLAKKSANGK-AISYKGNIVLSPRALYDLLS 220
Query: 241 YALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVT 300
Y L PAFS E + + + L K+GE++ + ITI DD + ++ + DGEG T+K
Sbjct: 221 YTLMPAFSAENVQRDRSVLKGKIGEQIFGENITIIDDGTLDYALYSSKCDGEGTATQKTV 280
Query: 301 LIEEGIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEIIGEI 360
L+E G+ K +++D A G STG+ R +R N + +E + +
Sbjct: 281 LVENGVLKNYLYDIKRANREGKTSTGNASRGYRSLPYVSPTNFII-----KETKNSLDDF 335
Query: 361 KHGYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVVGSTVFLIAGNVYELLKQA 416
+ G+ G+H+SNP G+FAV +Y ++G+++ + GN++E+ K+A
Sbjct: 336 DEYVYINGVIGSHTSNPITGDFAVEIQNSYYYKNGKIIPIKRGMFGGNIFEMFKEA 391
>pir||B69009 conserved hypothetical protein MTH1070 - Methanobacterium
thermoautotrophicum (strain Delta H)
>gi|2622168|gb|AAB85559.1| (AE000877) conserved protein
[Methanobacterium thermoautotrophicum]
Length = 430
Score = 143 bits (358), Expect = 3e-33
Identities = 113/442 (25%), Positives = 205/442 (45%), Gaps = 20/442 (4%)
Query: 8 EELIKYGEKFFDELEIVVRRSRGIEVNVELNEISMGATRIEKVTII--RGIKDKRVGIAI 65
EE +K ++ + E+ + R + +EV ++ + I G +IE +T I R +K+ R+G A
Sbjct: 6 EEAVKLALRYGEMAEVYIEREKTLEVEIQRDLIDFG--KIESMTGIGIRILKEGRMGFAY 63
Query: 66 IDTDSKEEVKKAIEEAAKMAKLNTPDEKWSSLPSPGKYREKPKVSE-DLKSVSTETLVEF 124
T + V A+ AA+ +L PDE + P Y + + + E VE
Sbjct: 64 --TSDPDGVDVAVRMAAQNLQLADPDENFG-FSEPSTYPSVKGIHDRSFDDLEVEDSVEM 120
Query: 125 VTRGIKLARESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKKEGVV 184
R I E T G +A S E I NS+G+ S + G+
Sbjct: 121 AGRMINRVLEEGCKPTSGGFTA--SRIETFILNSEGVEESSSSTGFSAHISVTAGENGMK 178
Query: 185 TPGIFDFDAKDNLELDVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAISGLLSYALF 244
T ++ D+ L+++ E V R + + + ++ + A +GLL
Sbjct: 179 TTA-YESDSSCKLDINPEWVAGRACRIARDSMGGRSIESGRIPAVLDYHAAAGLLG-TFA 236
Query: 245 PAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVTLIEE 304
AFS + + + + LAD++G +V + +++YDD E + A DGEG P+++ L+E+
Sbjct: 237 GAFSADNVQRGRSVLADRIGSQVTGEGLSVYDDGTLEGGLGSAPFDGEGTPSQRTALVED 296
Query: 305 GIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEIIGEIKHGY 364
GI +G++ + Y A +STG+G R + N + + L + G
Sbjct: 297 GILRGYMHNIYTASKGRADSTGNGLRGYMEVPAVSTTNFILEFDSTVPLDDF-----RGI 351
Query: 365 LVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVVGSTVFLIAGNVYELLKQATEVSKDQR 424
V + GAH++NP +G+F+V AN A++ + GE +++GN++EL+ + + ++R
Sbjct: 352 FVTDVLGAHTANPISGDFSVEANNAFMADSGEFTPVKKAMLSGNIFELMMKVSSTDLERR 411
Query: 425 ALPFMTTAITPYIKFENVKIAG 446
+ TA + E+V + G
Sbjct: 412 QVGGFVTA---PLMVEDVHVTG 430
>pir||E70461 pmbA protein - Aquifex aeolicus >gi|2984159|gb|AAC07693.1|
(AE000761) peptide maturation [Aquifex aeolicus]
Length = 441
Score = 138 bits (344), Expect = 1e-31
Identities = 129/460 (28%), Positives = 205/460 (44%), Gaps = 43/460 (9%)
Query: 7 MEELIKYGEKFFDELEIVVRRSRGIEVNVELNEISMGATRIEKVTIIRGIKDKRVGIAII 66
+E L+K K E E+ R + +++ V ++ ++ E+ IR +KDKR+G +
Sbjct: 4 LENLVKKYIKPGYEYEVFFERVKKLKIEVSNEQVENVSSSEERGIGIRVLKDKRLGFSYT 63
Query: 67 DTDSKEEVKKAIEEAAKMAKLNTPDEKWSSLPSPGKYREKPKVSEDLKSVSTETLVEFVT 126
+EE+K +E+A +M ++ PDE + + E+ S+ + +E
Sbjct: 64 SFLGEEEIKDTVEKAMEMCEIQEPDEANGFIEKLKPSKAVSVYDEESLSIPLQEKMEIPV 123
Query: 127 RGIKLARESDPNVTVAGGSAGTSWA-EVEIFNSQGINVSQEFGSAHIFFEFVGKKEGVVT 185
+ K A+E D + S T EV FNS G+ EFG + + T
Sbjct: 124 KMEKYAKELDKRIVGVRKSTLTEVEFEVRSFNSFGV----EFG-----YRGTSYTSMIAT 174
Query: 186 PGIFDFDAKDNLELDVEGVVNRGLERVK---WAYNVKEA-------------KNEETTVI 229
G + D+ + E RG R+K W V++A + V+
Sbjct: 175 LGTENDDSAISWEF-------RGARRLKNLNWKSMVEDAVFKTVNLLHPSPFETRSMPVV 227
Query: 230 FGPWAISGLLSYALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIA 289
F + + LL A P F G+ LVK T L DKV E VAS+ IT+ DD E +
Sbjct: 228 FFRESFAMLLD-AFSPMFLGDYLVKGKTLLKDKVNEIVASEKITLVDDGSMEEGFSTFPY 286
Query: 290 DGEGVPTRKVTLIEEGIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENG 349
D EGVPTRK LI++G+FKGF+ Y A+ E TG+ R S G + +E G
Sbjct: 287 DAEGVPTRKNLLIDKGVFKGFLHSLYTARKSSQEPTGNSVRGSYKELPSSGTTNFYLEKG 346
Query: 350 KRELSEIIGEIKHGYLVEGLQGAHSSNPDNGNFAVTANPAYL---IEDGEVVGSTVFLIA 406
E++ +LV + G H+ + +G+F++ + +D V G TV A
Sbjct: 347 NLSFEELLSYYDEVFLVLEVMGLHTVDTISGDFSLGCSGILYKKGKKDKTVRGITV---A 403
Query: 407 GNVYELLKQATEVSKDQRALPFMTTAITPYIKFENVKIAG 446
GN+ +LLK EV D L F + +P + + + + G
Sbjct: 404 GNILDLLKNVEEVGND---LTFYGSVGSPSVLVKKLTLGG 440
>gb|AAD53904.1|AF176314_14 (AF176314) PmbA [Zymomonas mobilis]
Length = 448
Score = 120 bits (298), Expect = 3e-26
Identities = 112/436 (25%), Positives = 200/436 (45%), Gaps = 18/436 (4%)
Query: 19 DELEIVVRRSRGIEVNVELNEIS-MGATRIEKVTIIRGIKDKRVGIAIIDTDSKEEVKKA 77
D ++V + + +++V L ++ +G + ++ + I + ++ D SKE +
Sbjct: 24 DAADVVFVQGQSQDISVRLGQLEDVGRSEGAEIGLRLFIGHRSASVSSSDF-SKEALDAL 82
Query: 78 IEEAAKMAKLNTPDEKWSSLPSPGKYRE--KPKV-SEDLKSVSTETLVEFVTRGIKLARE 134
+E A MA+ P+++W+ L + P++ S+D K ++ L E + AR
Sbjct: 83 VERAVAMAR-EAPEDRWAGLAPKELLMQGTAPEIESDDGKEIAPAVLRELALKAEDAARS 141
Query: 135 SDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKKEGVVTPGIFDFDAK 194
D G SA + S+G S++ V +GV +DF A
Sbjct: 142 VDGITNSEGASASAGRTIFALATSEGFTRGSS-SSSYGCSACVIAGQGVNMQRDYDFHAT 200
Query: 195 DNLE-LDVEGVVN-RGLERVKWAYNVKEAKNEETTVIFGPWAISGLLSYALFPAFSGERL 252
E LD ++ R ER N + + +IF P SG LSY L SG +
Sbjct: 201 RYFEDLDAAELIGTRAAERTIARLNPTRIDSGQMPIIFDPRVGSGFLSY-LIQGISGGAI 259
Query: 253 VKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVTLIEEGIFKGFIW 312
+KT+ L D +G+ V ++ ITI +D + + IA DGEG+PT+ +I++G G++
Sbjct: 260 TRKTSFLLDSLGKPVFNEGITIKEDPWRKRGIASRAFDGEGLPTKPNNIIDKGRLNGWLL 319
Query: 313 DNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEIIGEIKHGYLVEGLQGA 372
D+ A+ G TGH +R GG S G + +E GK E++ +IK G V + G+
Sbjct: 320 DSAAARQLGMTPTGHARRG-VGGPPSTGTANLYLEAGKVTPEELMSDIKLGIYVTEMIGS 378
Query: 373 HSSNPDNGNFAVTANPAYLIEDGEVVGSTV-FLIAGNVYELLKQATEVSKDQRALPFMTT 431
N G+++ A+ ++I DG++ +AGN+ ++ Q + L F
Sbjct: 379 -GVNMITGDYSRGAS-GFIIRDGQLAEPVAEITVAGNLKDIFMQMVPAND----LRFRRG 432
Query: 432 AITPYIKFENVKIAGK 447
P ++ + + +AG+
Sbjct: 433 TEVPTLRVDGLMVAGQ 448
>pir||B75213 pmba protein (tlde protein) PAB0155 - Pyrococcus abyssi (strain
Orsay) >gi|5457662|emb|CAB49153.1| (AJ248283) PMBA
PROTEIN (TLDE PROTEIN) [Pyrococcus abyssi]
Length = 427
Score = 120 bits (297), Expect = 4e-26
Identities = 101/387 (26%), Positives = 183/387 (47%), Gaps = 23/387 (5%)
Query: 39 EISMGATRIEKVTIIRGIKDKRVGIAIIDTDS--KEEVKKAIEEAAKMAKLNTPDEKWSS 96
E+ G+ + +R + ++G + I + +E++++ ++ A K+AK+ +
Sbjct: 42 EVERGSFEVSGGIGLRVLTQGKIGFSYISGSNFTREQLERLVKRAYKIAKV--AGSIYPG 99
Query: 97 LPSPGKYREKPKVSED-LKSVSTETLVEFVTRGIKLARESDPNVTVAGGSAGTSWAEVEI 155
P P K+ + +D ++++STE +VE+ T + + PN A S G S +E I
Sbjct: 100 FPVPKKFPNVRGLYDDKIRNLSTEEIVEYGTELVDVP----PN---AEASIGLSTSERGI 152
Query: 156 FNSQGINVSQEFGSAHIFFEFVGKKEGVVTPGIFDFDAKDNLELDVEGVVNRGLERVKWA 215
NS G +E + F +V +K F LE ++EGV + L + +
Sbjct: 153 MNSNGTEGREE-RTLLAFGLYVFEKSKGTGSYSKSFRRLPKLESEIEGVREKALWEFEMS 211
Query: 216 YNVKEAKNEETTVIFGPWAISGLLSYALFPAFSGERLVKKTTPLADKVGEKVASDVITIY 275
++ + +I P A++ +LS L P S + K + + +G +VAS +TI
Sbjct: 212 SKARKLEKYNGEIILEPKAVASILSIFL-PNVSARNVYLKRSRFTE-LGIEVASGGLTII 269
Query: 276 DDTFHELSIAKAIADGEGVPTRKVTLIEEGIFKGFIWDNYWAKVYGTESTGHGQRDWRGG 335
DD E I DGEG P + +I+EGI F+ D + + G STG+ R +
Sbjct: 270 DDPTVEGGINSYSFDGEGNPGVRKFIIKEGILSSFLADQKYGHLIGIGSTGNASRGY-SS 328
Query: 336 GVSIGLNSAVIENGKRELSEIIGEIKHGYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDG 395
SI ++ +I G E E G + G+ G H++N +G+F++ + Y++ G
Sbjct: 329 QPSISPSNIMISPGNDEQDE-------GIFIRGIYGEHTANSVSGDFSLNVDLGYVVRGG 381
Query: 396 EVVGSTVFLIAGNVYELLKQATEVSKD 422
E+ ++ GNV+E+LK T + K+
Sbjct: 382 EIRPFKGNMLVGNVFEMLKNVTNIGKE 408
>gb|AAK40966.1| Zn-dependent protease, tldE protein homolog, putative (tldE)
[Sulfolobus solfataricus]
Length = 419
Score = 117 bits (291), Expect = 2e-25
Identities = 118/420 (28%), Positives = 203/420 (48%), Gaps = 43/420 (10%)
Query: 22 EIVVRRSRGIEVNVELNEISMGATRIEK----VTIIRGIKDKRVGIAIIDTD-------S 70
E ++ R++ + +++E+ + M I K V II +++ GI +ID +
Sbjct: 3 ERLISRAKAMGISLEIFSVKMREYTIAKDKFYVPII--VEETGYGIRLIDEKYRIGYIYT 60
Query: 71 KEEVKKAIEEAAKMAKLNTPDEKWSSLPS--PGKYREKPKVSEDLKSVSTETLVEFVTRG 128
K+ +EEA K+AKL D K + LPS P K + +++ED+ + + L+E
Sbjct: 61 KKLNDNVLEEALKIAKLGESD-KANILPSKQPVKRINENQINEDVVQDTIKDLIEL---- 115
Query: 129 IKLARESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKKEGVVTPGI 188
E N+T A SA EV IFN++G+ VS++ G + +G +P I
Sbjct: 116 -----EEKVNLTSASASAINY--EVSIFNTEGVEVSEKRGVLSVQ---ASANDGNNSPEI 165
Query: 189 FDFDAKDNLELDVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAISGLLSYALFPA-F 247
+++ K + ++ +E + +E+VK + + V F A+ L S +LFP+ F
Sbjct: 166 YEYLIKRDSKISLEKLKASIIEKVKIMKKKERIDPKGYDVTFTQKALDSLFS-SLFPSLF 224
Query: 248 SGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVTLIEEGIF 307
S K+T+P K+GE V ++ I D L +++ D EG P+R +IE G+
Sbjct: 225 SARNFYKETSPF--KLGELVNENLEIIDDPLNQSLPFSRSF-DDEGNPSRVSKVIESGLV 281
Query: 308 KGFIWDNYWAKVYGTESTGHGQR--DWRGGGVSIGLN---SAVIENGKRELSEIIGEIKH 362
K + + YWA E+T R DW I + S +I + K S I ++
Sbjct: 282 KRPLTNTYWATRMSVENTSSASRNLDWVVPSYFIPPHVDFSNIIFDYKNTESNIE---EN 338
Query: 363 GYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVVGSTVFLIAGNVYELLKQATEVSKD 422
+V+ L+G +++ +GNF++ AN ++L E +G LI GN+ +LLK SK+
Sbjct: 339 SVIVDQLEGIDTADLSSGNFSLVANVSWLNRKDEKIGLEELLITGNLKQLLKNIVSTSKN 398
>emb|CAB57641.1| (Y18930) hypothetical protein [Sulfolobus solfataricus]
Length = 419
Score = 117 bits (291), Expect = 2e-25
Identities = 118/420 (28%), Positives = 203/420 (48%), Gaps = 43/420 (10%)
Query: 22 EIVVRRSRGIEVNVELNEISMGATRIEK----VTIIRGIKDKRVGIAIIDTD-------S 70
E ++ R++ + +++E+ + M I K V II +++ GI +ID +
Sbjct: 3 ERLISRAKAMGISLEIFSVKMREYTIAKDKFYVPII--VEETGYGIRLIDEKYRIGYIYT 60
Query: 71 KEEVKKAIEEAAKMAKLNTPDEKWSSLPS--PGKYREKPKVSEDLKSVSTETLVEFVTRG 128
K+ +EEA K+AKL D K + LPS P K + +++ED+ + + L+E
Sbjct: 61 KKLNDNVLEEALKIAKLGESD-KANILPSKQPVKRINENQINEDVVQDTIKDLIEL---- 115
Query: 129 IKLARESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKKEGVVTPGI 188
E N+T A SA EV IFN++G+ VS++ G + +G +P I
Sbjct: 116 -----EEKVNLTSASASAINY--EVSIFNTEGVEVSEKRGVLSVQ---ASANDGNNSPEI 165
Query: 189 FDFDAKDNLELDVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAISGLLSYALFPA-F 247
+++ K + ++ +E + +E+VK + + V F A+ L S +LFP+ F
Sbjct: 166 YEYLIKRDSKISLEKLKASIIEKVKIMKKKERIDPKGYDVTFTQKALDSLFS-SLFPSLF 224
Query: 248 SGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVTLIEEGIF 307
S K+T+P K+GE V ++ I D L +++ D EG P+R +IE G+
Sbjct: 225 SARNFYKETSPF--KLGELVNENLEIIDDPLNQSLPFSRSF-DDEGNPSRVSKVIESGLV 281
Query: 308 KGFIWDNYWAKVYGTESTGHGQR--DWRGGGVSIGLN---SAVIENGKRELSEIIGEIKH 362
K + + YWA E+T R DW I + S +I + K S I ++
Sbjct: 282 KRPLTNTYWATRMSVENTSSASRNLDWVVPSYFIPPHVDFSNIIFDYKNTESNIE---EN 338
Query: 363 GYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVVGSTVFLIAGNVYELLKQATEVSKD 422
+V+ L+G +++ +GNF++ AN ++L E +G LI GN+ +LLK SK+
Sbjct: 339 SVIVDQLEGIDTADLSSGNFSLVANVSWLNRKDEKIGLEELLITGNLKQLLKNIVSTSKN 398
>pir||B71249 hypothetical protein PH0249 - Pyrococcus horikoshii
>gi|3256638|dbj|BAA29321.1| (AP000001) 426aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 426
Score = 113 bits (279), Expect = 5e-24
Identities = 102/440 (23%), Positives = 197/440 (44%), Gaps = 27/440 (6%)
Query: 4 VGEMEELIKYGEKFFDELEIVVRRSRGIEVN---VELNEISMGATRIEKVTIIRGIKDKR 60
V ++E+L+K + F E EI + + + + EI R+ +R + +
Sbjct: 3 VDDVEKLVKILKSFDVEWEIYWESASSLSLKFRKIRRAEIERSTYRVSSGIGLRILVGGK 62
Query: 61 VGIAIIDTD--SKEEVKKAIEEAAKMAKLNTPDEKWSSLPSPGKYREKPKVSEDLKSVST 118
+G + + SK+E++ ++ A K+AK++ + + + P PGKY ++ +
Sbjct: 63 IGFSYLSGSDFSKDELELLVKRALKIAKISGTE--YPAFPVPGKY-------PSIRGLYD 113
Query: 119 ETLVEFVTRGIKLARESDPNVTVAG-GSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFV 177
+ +V+ + N+ V G S GTS I NS G+ S+ +
Sbjct: 114 KRIVDLSIEDLSYYGTELVNIEVFGEASIGTSTGIRGIMNSNGVEGSENRSLLTLGLYAY 173
Query: 178 GKKEGVVTPGIFDFDAKDNLELDVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAISG 237
K +G + G F ++E VE + + K + K+ + E +I P A+
Sbjct: 174 EKGKGSGSYGK-SFRVLPDMEKVVEEIKETAMFEFKLSREAKKIEKYEGEIIIEPKALIS 232
Query: 238 LLSYALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTR 297
LS + P S + + K + +++G +V+S+ +I DD + + DGEG P
Sbjct: 233 FLSIFV-PNVSAKSVYMKRSRF-ERLGVEVSSESFSIIDDPTIDEGLGSYSFDGEGNPGM 290
Query: 298 KVTLIEEGIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEII 357
+ +I++G+ F+ D + + G STG+ R + + I ++ +I +G L E
Sbjct: 291 RKFIIKDGVLTSFLSDQKYGSLLGIGSTGNAIRSYSSQPI-IDSSNLLIPSGNETLDE-- 347
Query: 358 GEIKHGYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVVGSTVFLIAGNVYELLKQAT 417
G + + G H++NP G+F++ Y++ + V +I GN++E+LK T
Sbjct: 348 -----GIFIRSVYGEHTANPITGDFSLNIELGYIVNNRGVKPFKGNMIVGNIFEMLKNVT 402
Query: 418 EVSKDQRAL-PFMTTAITPY 436
+ K+ L F+ IT +
Sbjct: 403 SIDKNVEILDDFIAPKITTW 422
>pir||E72342 pmbA-related protein - Thermotoga maritima (strain MSB8)
>gi|4981252|gb|AAD35809.1|AE001743_11 (AE001743)
pmbA-related protein [Thermotoga maritima]
Length = 435
Score = 106 bits (263), Expect = 4e-22
Identities = 102/447 (22%), Positives = 197/447 (43%), Gaps = 29/447 (6%)
Query: 15 EKFFDELEIVVRRSRGIEVNVELNEISMGATRIEKVTI------------IRGIKDKRVG 62
E+F D L + +++ G+EV + E + R+ + I+ +KD + G
Sbjct: 4 EEFKDRLFALAKKN-GVEVQISFLETREFSLRLANGDLDQYTDAGKFNVEIKVLKDGKTG 62
Query: 63 IAIIDTDSKEEVKKAIEEAAKMAKLNTPDEKWSSLPSPGKYREKPKVSEDLKSVSTETLV 122
T E +K EEA ++ +EK +YRE + +S + +
Sbjct: 63 T--FRTQVLENPEKCFEEALSNLQVKDSEEKEYFFEGGKEYREMETYVGRFEKLSVKEKM 120
Query: 123 EFVTRGIKLARESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKKEG 182
+ + + A + + V V + I N+ G++V + +F + +
Sbjct: 121 DMAKKAHESAAKDERVVMVPTVMYKDMVIKKIITNTLGLDVESQMDGGFLFAMAIARDAN 180
Query: 183 VVTPGIFDFDAKDNLELDVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAISGLLSYA 242
+ ++ A+ +L+ E + R E K + + V+ A+ L+
Sbjct: 181 PRSGSWYEL-ARTPEDLNPEEIGKRAAEEAISLIGSKTIPSGKYPVLMRNTALLDLMEMF 239
Query: 243 LFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVTLI 302
+ P S E + K +PL K+GE+V + ++I D +H ++ D EGVPT + ++
Sbjct: 240 I-PMISAENVQKNLSPLKGKLGEQVGNPAVSIKDLPYHPKGLSSTPFDDEGVPTTEKFVL 298
Query: 303 EEGIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEIIGEIKH 362
E G+ K F+ + A+ G E TG+G + GG + L ++ G++ E++ E+
Sbjct: 299 ENGVLKTFLHNLKTARKEGVEPTGNG---FVGGIRPVNL---MLMPGEKSFEELLKEMDR 352
Query: 363 GYLVEGLQGAHS-SNPDNGNFAVTANPAYLIEDGEVV-GSTVFLIAGNVYELLKQATEVS 420
G ++ ++G H+ +N +G F++ A Y +E+GE+ G I+GN +LL++ V
Sbjct: 353 GVVITEVEGMHAGANSISGEFSLFAK-GYWVENGEIAHGVEDITISGNFLDLLRKIVLVG 411
Query: 421 KDQRALPFMTTAITPYIKFENVKIAGK 447
D + I P + E + +AGK
Sbjct: 412 NDVKV---SQHTIAPSVLVEVLDVAGK 435
>pir||S77207 hypothetical protein slr1435 - Synechocystis sp. (strain PCC 6803)
>gi|1652621|dbj|BAA17541.1| (D90907) PmbA protein
[Synechocystis sp.]
Length = 427
Score = 106 bits (261), Expect = 7e-22
Identities = 107/434 (24%), Positives = 200/434 (45%), Gaps = 34/434 (7%)
Query: 19 DELEIVVRRSRGIEVNVELNEISMGATRIEKVTIIRGIKDKRVGIAIIDTDSKEEVKKAI 78
+ E+ RS V E N + + + +R K+ + G+A+ + E+ +
Sbjct: 18 ESAEVYYSRSFSRPVFFEANRLKQLESSESEGVALRLWKNGQAGLAVAYGPVEPEI--LV 75
Query: 79 EEAAKMAKLNTPDEKWSSLPSPGKYREKPKVSEDLKSVSTETLVEFVTRGIKLARESDPN 138
E+A +A LN P+ + P YRE + ED VS E L+++ I R
Sbjct: 76 EKALALAALNPPNPPRFTAPRQD-YRES--LGED---VSVEQLIDWGQTAIASLRSEFAE 129
Query: 139 VTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFF--EFVGKKEGVVTPGIFDFDAKDN 196
V + G S + NS+G++ + S +F E++ ++ + I+D +
Sbjct: 130 V-LCSGELACSTDSTRLINSEGLDCTWTERSLSYYFGVEWIRGEDFLA---IYDGEQCRG 185
Query: 197 LELDVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAISGLLSYALFPAFSGERLVKKT 256
+ +V VV +R+ W ++ + + ++ A S LL + A G+R+ + +
Sbjct: 186 -QTNVGQVVENLRQRLLWVEVNQQIQGGKMPILLTSGAAS-LLWDTVGEALHGQRVAEDS 243
Query: 257 TPLADKVGEKVASDVITIYDDTFHELSIAKAIA-----DGEGVPTRKVTLIEEGIFKGFI 311
+P A+K+G+ VA + + I D AI D EG T+K+ LI+ G F
Sbjct: 244 SPWAEKLGQTVAIEELNISQDP-------TAIPFDCPFDDEGSRTQKLALIKNGKIAQFY 296
Query: 312 WDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEIIGEIKHGYLVEGLQG 371
D+ A+ GT +TG+G R G GL + +I G +++ ++ +G +V+ + G
Sbjct: 297 TDHETAEKLGTTTTGNGFRPSLGSAPQPGLVNMLITPGTASFDQLLKKLGNGLVVDQILG 356
Query: 372 AHSSNPDNGNFAVTANPAYLIEDGEVVGSTV-FLIAGNVYELLKQATEVSKDQRALPFMT 430
+ +G+F++ + Y +++GE+ G +++GN+YELL Q + D+R +
Sbjct: 357 GGAD--ISGDFSINVDLGYRVQNGEITGRVKDTMVSGNIYELLNQIIALGSDRR---WQG 411
Query: 431 TAITPYIKFENVKI 444
+ TP I + V I
Sbjct: 412 SCATPSIILDGVSI 425
>pir||F75033 hypothetical protein PAB1548 - Pyrococcus abyssi (strain Orsay)
>gi|5458676|emb|CAB50163.1| (AJ248287) hypothetical
protein [Pyrococcus abyssi]
Length = 443
Score = 106 bits (261), Expect = 7e-22
Identities = 110/452 (24%), Positives = 197/452 (43%), Gaps = 22/452 (4%)
Query: 1 MDEVGEMEELI--KYGEKFFDELEIVVRRSRGIEVNVELNEISMGATRIEKVTIIRGIKD 58
M E+ ++ ELI K E F ++ ++ + ++ NE+++ E+ + +
Sbjct: 1 MVEMFDVNELILKKAKELGFGDVVVLSYETNRRQIRFANNEVTVAKHWNERKVELFVEWE 60
Query: 59 KRVGIAIIDTDSKEEVKKAIEEA-AKMAKLNTPDEKWSSLPSPGKYREKPKVSEDLKSVS 117
KR+ I ++E +++ ++ A + K+ ++ + P KY + P+ D V
Sbjct: 61 KRIAGTSITDLTEENIERTLKTLKANLEKMKPREDYYGIAEGPFKYEDIPETF-DKAIVE 119
Query: 118 TETLVEFVTRGIKLARESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFE-F 176
+ E+V R I A E G T ++ + S G+ E I F
Sbjct: 120 LDDPSEYVERAINAALEE--GAKRVAGVLYTDHDKIYLTTSNGVEAFDEGTGIEISVRAF 177
Query: 177 VGKKEGVVTPGIFDFDAKDNLELDVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAIS 236
+G E G + + D E + E K A N ++ + VIF P A +
Sbjct: 178 IGDLES----GHGTNSVRVLKKFDPESAGRKAGEIAKMARNPEQGPEGKFDVIFDPLAFA 233
Query: 237 GLLSYALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPT 296
LLSY + AFS + + A+K+ +KVAS+V+TI D D EGVPT
Sbjct: 234 NLLSYMGW-AFSAFAVEAGFSYFANKLDQKVASEVVTIKDIGNLPNGYGTRKFDDEGVPT 292
Query: 297 RKVTLIEEGIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEI 356
R+ LIE G K ++++ AK YG E+T + G +S + V+E G E+
Sbjct: 293 RETVLIERGTLKTYLFNTSLAKKYGKETTAN------AGLISPRAWNIVLEPGDYTKDEL 346
Query: 357 IGEIKHGYLVEGLQGAHSSNPDNGNFA-VTANPAYLIEDGEVVGSTVFLIAGNVYELLKQ 415
E+K G + + N G+F+ + + +LIE+GE+ ++ N+ +L+
Sbjct: 347 FQEVKRGIYITNVWYTRFQNYMTGDFSTIPRDGIFLIENGELKPIRNIRVSDNMLRILQN 406
Query: 416 ATEVSKDQRALPFMTTA---ITPYIKFENVKI 444
++K+ + + + TPY+ + V I
Sbjct: 407 IVGLTKESHHVHWWEVSRPVTTPYVLVKEVGI 438
>gi|11498264 antibiotic maturation protein (pmbA) [Archaeoglobus fulgidus]
>gi|7429843|pir||H69331 hypothetical protein AF0656 -
Archaeoglobus fulgidus >gi|2649962|gb|AAB90584.1|
(AE001059) antibiotic maturation protein (pmbA)
[Archaeoglobus fulgidus]
Length = 391
Score = 104 bits (257), Expect = 2e-21
Identities = 104/427 (24%), Positives = 190/427 (44%), Gaps = 40/427 (9%)
Query: 20 ELEIVVRRSRGIEVNVELNEISMGATRIEKVTIIRGIKDKRVGIAIIDTDSKEEVKKAIE 79
E E+ R++GI +E + + ++ ++K R I RVG A T + A+
Sbjct: 2 EWEVFEYRTKGIMAEIEAGRLKIVSSYVDKSFSARVILKGRVGFASASTRDE-----ALS 56
Query: 80 EAAKMAKLNTPDEKWSSLPSPGKYREKPKVSEDLKSVSTETLVEFVTRGIKLARESDPNV 139
A K+A+++ +++ P+ K + ++ +E ++E R R +
Sbjct: 57 LAEKIARIS--EDELEDFPNEKPASVKGIYDKRVEEADSELIMEEFER----LRSAVEKA 110
Query: 140 TVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKKEGVVTPGIFDFDAKDNLEL 199
+A + + EV I NS G++ ++ S+ + E V + ++ ++EL
Sbjct: 111 NIASATIEHAVEEVRITNSFGLDSREKSTSSSMIVEAVFEGGSA-----YEVCGSRSIEL 165
Query: 200 DVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAISGLLSYALFPAFSGERLVK--KTT 257
D+EG + E + + + VI P A+ LLS L+P+ S E + K
Sbjct: 166 DIEGAAKKAEELAVDSAKAIKIEGGTYDVILQPIAVHQLLSNTLYPSLSAENVEKGRSVI 225
Query: 258 PLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVTLIEEGIFKGFIWDNYWA 317
L D+ G IT+ DD E + D EGV RK LI+ G+ + + D +
Sbjct: 226 RLGDEFGR------ITVIDDPTVEGGLMSCGFDDEGVSARKTFLIDNGVVRSYYTDWKHS 279
Query: 318 KVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEIIGEIKHGYLVEGLQGAHSSNP 377
K YG TG+G R + +++ V+E + + + L G+H++NP
Sbjct: 280 KKYGV--TGNGFRLEESSFPAPMVSNVVLEVDDADDDNCL-------TIHSLIGSHTANP 330
Query: 378 DNGNFAVTANPAYLIEDGEVVGSTVFLIAGNVYELLKQATEVSKDQRALPFMTTAITPYI 437
+G+F++ N AY E V G+ ++ GNV+ELLK +V L + +T +
Sbjct: 331 VSGDFSLECNNAYFGEKA-VKGAMIY---GNVFELLK---KVEGGLGELRQIENTVTKSL 383
Query: 438 KFENVKI 444
+F +V++
Sbjct: 384 RFRSVRV 390
>pir||E71135 hypothetical protein PH0849 - Pyrococcus horikoshii
>gi|3257260|dbj|BAA29943.1| (AP000003) 443aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 443
Score = 99.1 bits (243), Expect = 9e-20
Identities = 110/453 (24%), Positives = 198/453 (43%), Gaps = 24/453 (5%)
Query: 1 MDEVGEMEELI--KYGEKFFDELEIVVRRSRGIEVNVELNEISMGATRIE-KVTIIRGIK 57
M E+ E+ ELI K E ++ ++ + +V NE+++ E KV + K
Sbjct: 1 MMEMFEVNELILKKAKELGLGDVVVLSYETDRRQVRFANNEVTVAKHWHERKVELFVEWK 60
Query: 58 DKRVGIAIIDTDSKEEVKKAIEEA-AKMAKLNTPDEKWSSLPSPGKYREKPKVSEDLKSV 116
+ G +I D S+E +++ ++ A + K+ ++ + P +Y++ P+ D +
Sbjct: 61 KRIAGTSITDL-SEENIERTLKTLKANLEKMKPKEDYYGIAEGPFEYKDIPETF-DKAII 118
Query: 117 STETLVEFVTRGIKLARESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFE- 175
+ E+V I A E G T ++ + S + E I
Sbjct: 119 ELDDPSEYVETAINAALEE--GAKRVAGVLYTDHDKIYLTTSNDVEAFDEGTGIEISVRA 176
Query: 176 FVGKKEGVVTPGIFDFDAKDNLELDVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAI 235
F+G E G + + D E + E K A N ++ VIF P A
Sbjct: 177 FIGDLES----GHGTNSVRVLKKFDPESAGRKAGEIAKLARNPEQGPEGRFDVIFDPLAF 232
Query: 236 SGLLSYALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVP 295
+ LLSY + AFS + + A+K+ +KVAS+++TI D A D EGVP
Sbjct: 233 ANLLSYMGW-AFSAFAVEAGFSYFANKLDQKVASEIVTIKDVGNLPNGYATRKFDDEGVP 291
Query: 296 TRKVTLIEEGIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSE 355
T++ LI +GI K ++++ AK YG E+T + G ++ + V+E G E
Sbjct: 292 TKETILIHKGILKTYLFNTSLAKKYGRETTAN------AGLIAPRAWNIVLEPGDYTKDE 345
Query: 356 IIGEIKHGYLVEGLQGAHSSNPDNGNFA-VTANPAYLIEDGEVVGSTVFLIAGNVYELLK 414
+ E+K G + + N G+F+ + + +LIE+GE+ ++ N+ +L+
Sbjct: 346 LFQEVKKGIYITNVWYTRFQNYMTGDFSTIPRDGIFLIENGELKPIRNIRVSDNMLRILQ 405
Query: 415 QATEVSKDQRALPFMTTA---ITPYIKFENVKI 444
+SK+ + + + TPY+ + V I
Sbjct: 406 NVVALSKESYHVHWWEVSRPVTTPYVLVKEVGI 438
>pir||D64424 tldD homolog MJ0996 - Methanococcus jannaschii
Length = 451
Score = 91.3 bits (223), Expect = 2e-17
Identities = 102/420 (24%), Positives = 179/420 (42%), Gaps = 57/420 (13%)
Query: 36 ELNEISMGATRIEKVT-------IIRGIKDKRVGIAIIDTDSKEEVKKAIEEAAKMAKLN 88
E N I++ +IE+++ +R + G + S+EE++K I +A KMAK++
Sbjct: 25 ESNTITLKDGKIEEISSGFGNGVAVRVLYKNGWGFVTSNIVSEEEIEKLINKAYKMAKIS 84
Query: 89 TPDEKWSSLPSPGKYREKPKVSEDLKS---------------VSTETLVEFVTRGIKLAR 133
+Y EK + +D K+ V E E + K
Sbjct: 85 N------------EYSEKEXILKDYKAIIDNYKMIGKINPTDVDIEEKKEIIIDTYK--N 130
Query: 134 ESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKKEGVVTPGI----- 188
+D + S + + S+G + E ++ V K+ G + G
Sbjct: 131 MTDEKIKSISVSYSDVFGKRIFMISEGSRIEGEITRCIMYMNCVAKENGNLQYGAERTGG 190
Query: 189 FDFDA-KDN-LELDVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAISGLLSYALFPA 246
F F+ KDN L L +E NR L +K K + VI P + A+ A
Sbjct: 191 FGFEKIKDNYLNLALEAK-NRALRLLK----AKPCPKGKFKVILDPELAGVFIHEAVGHA 245
Query: 247 FSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVTLIEEGI 306
+ +++ + DK+GE+V S+ +T+ DD E + D EGV +K +IE GI
Sbjct: 246 SEADLVLQNDSVFKDKLGERVGSEYVTVIDDATIEGAFGSYKYDDEGVEGKKTVIIENGI 305
Query: 307 FKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEIIGEIKHGYLV 366
K ++ A E TG+G+ + + + +++ I+ G E++ + K G +
Sbjct: 306 LKTYLHSRETAGRMDAELTGNGRAEGLNKPI-VRMSNTFIKPGDWSFEELLEDTKEGIFL 364
Query: 367 EGLQGAHSSNPDNGNFAVTANPAYLIEDGEVVGSTVFL----IAGNVYELLKQATEVSKD 422
+G +G + G F +A AYLIE+GE+ T L ++G + ++L + V+KD
Sbjct: 365 KGSRGG-QVDTGKGLFQFSAVEAYLIENGEL---TQVLKDAGLSGEILDILFKVDAVTKD 420
>sp|Q58403|Y996_METJA HYPOTHETICAL PROTEIN MJ0996 >gi|2826357|gb|AAB99001.1| (U67542)
conserved hypothetical protein [Methanococcus
jannaschii]
Length = 451
Score = 90.5 bits (221), Expect = 3e-17
Identities = 102/420 (24%), Positives = 179/420 (42%), Gaps = 57/420 (13%)
Query: 36 ELNEISMGATRIEKVT-------IIRGIKDKRVGIAIIDTDSKEEVKKAIEEAAKMAKLN 88
E N I++ +IE+++ +R + G + S+EE++K I +A KMAK++
Sbjct: 25 ESNTITLKDGKIEEISSGFGNGVAVRVLYKNGWGFVTSNIVSEEEIEKLINKAYKMAKIS 84
Query: 89 TPDEKWSSLPSPGKYREKPKVSEDLKS---------------VSTETLVEFVTRGIKLAR 133
+Y EK + +D K+ V E E + K
Sbjct: 85 N------------EYSEKEIILKDYKAIIDNYKMIGKINPTDVDIEEKKEIIIDTYK--N 130
Query: 134 ESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKKEGVVTPGI----- 188
+D + S + + S+G + E ++ V K+ G + G
Sbjct: 131 MTDEKIKSISVSYSDVFGKRIFMISEGSRIEGEITRCIMYMNCVAKENGNLQYGAERTGG 190
Query: 189 FDFDA-KDN-LELDVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAISGLLSYALFPA 246
F F+ KDN L L +E NR L +K K + VI P + A+ A
Sbjct: 191 FGFEKIKDNYLNLALEAK-NRALRLLK----AKPCPKGKFKVILDPELAGVFIHEAVGHA 245
Query: 247 FSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVTLIEEGI 306
+ +++ + DK+GE+V S+ +T+ DD E + D EGV +K +IE GI
Sbjct: 246 SEADLVLQNDSVFKDKLGERVGSEYVTVIDDATIEGAFGSYKYDDEGVEGKKTVIIENGI 305
Query: 307 FKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEIIGEIKHGYLV 366
K ++ A E TG+G+ + + + +++ I+ G E++ + K G +
Sbjct: 306 LKTYLHSRETAGRMDAELTGNGRAEGLNKPI-VRMSNTFIKPGDWSFEELLEDTKEGIFL 364
Query: 367 EGLQGAHSSNPDNGNFAVTANPAYLIEDGEVVGSTVFL----IAGNVYELLKQATEVSKD 422
+G +G + G F +A AYLIE+GE+ T L ++G + ++L + V+KD
Sbjct: 365 KGSRGG-QVDTGKGLFQFSAVEAYLIENGEL---TQVLKDAGLSGEILDILFKVDAVTKD 420
>pir||G71248 tldD homolog PH0246 - Pyrococcus horikoshii
>gi|3256635|dbj|BAA29318.1| (AP000001) 504aa long
hypothetical tldd protein [Pyrococcus horikoshii]
Length = 504
Score = 90.1 bits (220), Expect = 4e-17
Identities = 91/432 (21%), Positives = 184/432 (42%), Gaps = 29/432 (6%)
Query: 7 MEELIKYGEKFFDELEIVVRRSRGIEVNVELNEISMGATRIEKVTIIRGIKDKRVGIAII 66
++E++K EK+ EI + +++ +E E + KV + ++ VG+ ++
Sbjct: 52 IDEILKVLEKYSSSSEI-----KFMDIRMESIEYTELTIENGKVENLENNGERGVGVRVL 106
Query: 67 -------DTDSKEEVKKAIEEAAKMAKLNTPDEKWSSLPSPGKYREKPKVSEDLKSVSTE 119
T+ ++++ ++ A KMAK++ +S+ + + +V + +K +
Sbjct: 107 INGWGFASTNDLTKIEEIVKTAIKMAKVSRIS---TSVYTRDPIEDNVEVKQGIKLKDID 163
Query: 120 TLVEFVTRGIK----LARESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFE 175
L E V G++ L RE N+ S + +S+G + ++
Sbjct: 164 -LEEKVKLGVEVNNMLKRE---NIKTRKFSYSDIIVKKLYLSSEGSIIESTVPRVYLSIS 219
Query: 176 FVGKKEGVVTPGIFDFDAKDNLEL----DVEGVVNRGLERVKWAYNVKEAKNEETTVIFG 231
V K G + F E+ D E N ++ + + + E VI
Sbjct: 220 SVAKFSGKMQTYWKSFGGTGGWEIVEKIDFEHWANFVSKKAVSLLSARSPPSGEMQVIMD 279
Query: 232 PWAISGLLSYALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADG 291
P + AL A + + ++ + LA +G+++A + +T+ DD I D
Sbjct: 280 PELAGVFIHEALGHASEADAVKQEESILAGMLGKRIAVEELTVVDDPTLPGKFGSYIYDD 339
Query: 292 EGVPTRKVTLIEEGIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKR 351
EG+P ++V +I +G+ ++ D + + E GHG+ + +++ IE G
Sbjct: 340 EGIPGKRVEIIRDGVLVNYLNDRETSSLLNLEPNGHGRAQSYSHVPLVRMSNTYIEPGDW 399
Query: 352 ELSEIIGEIKHGYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVVGS-TVFLIAGNVY 410
EI+ E+K G + G +G + +GNF A YL+E+GE+ G ++GN+
Sbjct: 400 RFEEILDEVKFGVYMIGDKGG-QVDVASGNFMFAAKEGYLVENGEIKGHLRDVALSGNIL 458
Query: 411 ELLKQATEVSKD 422
L++ + D
Sbjct: 459 SALREIKAIGND 470
>pir||F81010 tldD protein NMB2066 [imported] - Neisseria meningitidis (group B
strain MD58) >gi|7227328|gb|AAF42385.1| (AE002556) tldD
protein [Neisseria meningitidis MC58]
Length = 480
Score = 89.7 bits (219), Expect = 6e-17
Identities = 96/419 (22%), Positives = 176/419 (41%), Gaps = 18/419 (4%)
Query: 14 GEKFFDELEIVVRRSRGIEVNVELNEISMGATRIEKVTIIRGIKDKRVGIAIIDTDSKEE 73
G D +I +R+ ++E + G+ +I + +R + + A D+ +
Sbjct: 31 GAHHVDYADIYCQRTAYESWHLEEGIVKSGSFQINQGVGVRAVSGDKTAFAYADSLCIDS 90
Query: 74 VKKAIEEAAKMAKLNTPDEKWSSLPSPGKYREKP--KVSEDLKSVSTETLVEFVTRGIKL 131
+ ++ A + + K S+ P + R KP S+ + + + V + + +
Sbjct: 91 INRS---ARAVRAIGAAGGKVSA-KMPSETRGKPVCSASDPIAGLDSAAKVALLNKVEAI 146
Query: 132 ARESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKKEGVVTPGIFDF 191
A+ +DP + + V + G + + + + K+ G
Sbjct: 147 AKAADPRIVQVMAGLTCEYDMVYLARLDGKHAADIRPMVRLNVTVIAKQGERREQGSAGG 206
Query: 192 DAKDNLELDVEGVVNRGLER-VKWAYNVKEAKNE---ETTVIFGPWAISGLLSYALFPAF 247
+ +L E +V+R ++ VK A E++ E TV+ G LL A+
Sbjct: 207 GGRYDLAYFDENLVHRFVDAAVKQALTNLESRPAPAGEMTVVLGNGWPGVLLHEAVGHGL 266
Query: 248 SGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVTLIEEGIF 307
G+ K T+ + ++GE+VA+ +T+ D D EG TR+ LIE+GI
Sbjct: 267 EGDFNRKGTSVFSGRIGERVAAKGVTVVDQGDIAGRRGSLNIDDEGNETRRTVLIEDGIL 326
Query: 308 KGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEIIGEIKHGYLVE 367
G++ D A++ GT+STG+G+R+ + + +ENG E EII I G
Sbjct: 327 VGYMQDETNARLTGTQSTGNGRRESYASAPMPRMTNTFMENGSYEPEEIIASIDKGIYAV 386
Query: 368 GLQGAHSSNPDNGNFAVTANPAYLIEDGE----VVGSTVFLIAGNVYELLKQATEVSKD 422
G + +G F +A+ A+ +E G V G+T I GN E+LK + + D
Sbjct: 387 NF-GGGQVDITSGKFVFSASEAWWVEGGRLQYPVKGAT---IIGNGPEVLKHVSMIGND 441
>sp|P46473|TLDD_ECOLI TLDD PROTEIN >gi|7429829|pir||F65116 tldD protein - Escherichia
coli (strain K-12) >gi|606183|gb|AAA58046.1| (U18997)
ORF_f481 [Escherichia coli] >gi|1732437|dbj|BAA07913.1|
(D44451) TldD protein [Escherichia coli]
>gi|1789640|gb|AAC76276.1| (AE000403) suppresses
inhibitory activity of CsrA [Escherichia coli K12]
Length = 481
Score = 88.9 bits (217), Expect = 1e-16
Identities = 101/399 (25%), Positives = 172/399 (42%), Gaps = 25/399 (6%)
Query: 40 ISMGATRIEKVTIIRGIKDKRVGIAIIDTDSKEEVKKAIEEAAKMAKLNTPDEKWSSLPS 99
I G+ I++ +R I ++ G A D S A+E++A+ A+ D + +
Sbjct: 55 IKDGSYNIDQGVGVRAISGEKTGFAYADQISL----LALEQSAQAARTIVRDSGDGKVQT 110
Query: 100 PGKYREKPKVS--EDLKSVSTETLVEFVTRGIKLARESDPNVTVAGGSAGTSWAEVEIFN 157
G P + + L+S+S E ++ + R K+ARE+D V S + + +
Sbjct: 111 LGAVEHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLSGVYELILVAA 170
Query: 158 SQGINVSQEFG----SAHIFFEFVGKKEGVVTPGIFDFDAKDNLELDVEGVVNRGL---E 210
+ G + S + E GK+E + G F + L D++G V E
Sbjct: 171 TDGTLAADVRPLVRLSVSVLVEEDGKRERGASGGGGRFGYEFFLA-DLDGEVRADAWAKE 229
Query: 211 RVKWAY---NVKEAKNEETTVIFGPWAISGLLSYALFPAFSGERLVKKTTPLADKVGEKV 267
V+ A + A V+ G LL A+ G+ + T+ + +VGE V
Sbjct: 230 AVRMALVNLSAVAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQVGELV 289
Query: 268 ASDVITIYDDTFHELSIAKAIADGEGVPTRKVTLIEEGIFKGFIWDNYWAKVYGTESTGH 327
AS++ T+ DD D EG P + LIE GI KG++ D A++ G TG+
Sbjct: 290 ASELCTVVDDGTMVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQDKLNARLMGMTPTGN 349
Query: 328 GQRDWRGGGVSIGLNSAVIENGKRELSEIIGEIKHGYLVEGLQGAHSSNPDNGNFAVTAN 387
G+R+ + + + GK EII +++G G + +G F + +
Sbjct: 350 GRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNF-GGGQVDITSGKFVFSTS 408
Query: 388 PAYLIEDGEVV----GSTVFLIAGNVYELLKQATEVSKD 422
AYLIE+G+V G+T + G+ E ++Q + V D
Sbjct: 409 EAYLIENGKVTKPVKGAT---LIGSGIETMQQISMVGND 444
>pir||A82033 TLDD protein homolog NMA0367 [imported] - Neisseria meningitidis
(group A strain Z2491) >gi|7379119|emb|CAB83668.1|
(AL162752) TLDD protein homolog [Neisseria meningitidis
Z2491]
Length = 480
Score = 87.8 bits (214), Expect = 2e-16
Identities = 95/419 (22%), Positives = 175/419 (41%), Gaps = 18/419 (4%)
Query: 14 GEKFFDELEIVVRRSRGIEVNVELNEISMGATRIEKVTIIRGIKDKRVGIAIIDTDSKEE 73
G D +I +R+ ++E + G+ +I + +R + + A D+ +
Sbjct: 31 GAHHVDYADIYCQRTAYESWHLEEGIVKSGSFQINQGVGVRAVSGDKTAFAYADSLCIDS 90
Query: 74 VKKAIEEAAKMAKLNTPDEKWSSLPSPGKYREKP--KVSEDLKSVSTETLVEFVTRGIKL 131
+ ++ A + + K S+ P + R KP S+ + + + V + + +
Sbjct: 91 INRS---ARAVRAIGAAGGKVSA-KMPSETRGKPVCSASDPIAGLDSAAKVALLNKVEAI 146
Query: 132 ARESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKKEGVVTPGIFDF 191
A+ +DP + + V + G + + + + K+ G
Sbjct: 147 AKAADPRIVQVMAGLTCEYDMVYLARLDGKHAADIRPMVRLNVTVIAKQGERREQGSAGG 206
Query: 192 DAKDNLELDVEGVVNRGLER-VKWAYNVKEAKNE---ETTVIFGPWAISGLLSYALFPAF 247
+ +L E +V + ++ VK A E++ E TV+ G LL A+
Sbjct: 207 GGRYDLAYFDENLVRQFVDAAVKQALTNLESRPAPAGEMTVVLGNGWPGVLLHEAVGHGL 266
Query: 248 SGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVTLIEEGIF 307
G+ K T+ + ++GE+VA+ +T+ D D EG TR+ LIE+GI
Sbjct: 267 EGDFNRKGTSVFSGRIGERVAAKGVTVVDQGDIAGRRGSLNIDDEGNETRRTVLIEDGIL 326
Query: 308 KGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEIIGEIKHGYLVE 367
G++ D A++ GT+STG+G+R+ + + +ENG E EII I G
Sbjct: 327 VGYMQDETNARLTGTQSTGNGRRESYASAPMPRMTNTFMENGSYEPEEIIASIDKGIYAV 386
Query: 368 GLQGAHSSNPDNGNFAVTANPAYLIEDGE----VVGSTVFLIAGNVYELLKQATEVSKD 422
G + +G F +A+ A+ +E G V G+T I GN E+LK + + D
Sbjct: 387 NF-GGGQVDITSGKFVFSASEAWWVEGGRLQYPVKGAT---IIGNGPEVLKHVSMIGND 441
>sp|P57478|TLDD_BUCAI TLDD PROTEIN HOMOLOG >gi|10039067|dbj|BAB13101.1| (AP001119) tldD
protein [Buchnera sp. APS]
Length = 483
Score = 87.8 bits (214), Expect = 2e-16
Identities = 90/360 (25%), Positives = 161/360 (44%), Gaps = 20/360 (5%)
Query: 53 IRGIKDKRVGIAIIDTDSKEEVKKAIEEAAKMAKLNTPDEKWSSLPSPGKYREKP--KVS 110
+R I+ + G A D S + ++++ ++A + L K +L K +P K
Sbjct: 68 VRAIRGESTGFAYSDQISLDSLRRSTKKAHSII-LTKGSGKTKTL---SKKTIEPIYKNV 123
Query: 111 EDLKSVSTETLVEFVTRGIKLARESDPNVTVAGGSAGTSWAEVEIFNSQG-----INVSQ 165
L+ S++ + + R +AR D V S S+ ++ + ++ G I S
Sbjct: 124 NPLEGFSSKEKTDLLYRANYIARSLDHRVIEVNASLTGSYEQILVASTDGNLVSDIRPSI 183
Query: 166 EFGSAHIFFEFVGKKE------GVVTPGIFDFDAKDNL-ELDVEGVVNRGLERVKWAYNV 218
+F S + E GK+E G T F + D+ E+ ++ + +
Sbjct: 184 QF-SISVLVEDHGKRERGRSGGGSRTDYNFFLNQDDSSKEIRIDHWSKEAVRIALLNLSS 242
Query: 219 KEAKNEETTVIFGPWAISGLLSYALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDT 278
KEA + V+ G LL A+ G+ K T+ + +G+KVAS++ TI DD
Sbjct: 243 KEALSGTFPVVLGSGWPGVLLHEAIGHGLEGDFNRKGTSIFTNMIGKKVASELCTIIDDG 302
Query: 279 FHELSIAKAIADGEGVPTRKVTLIEEGIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVS 338
+ D EG P +K LIE GI K ++ D A++ G +STG+G+R+
Sbjct: 303 TIKNQRGSLSIDDEGTPGQKNILIENGILKKYMQDKLNARLMGVKSTGNGRRESYSCLPM 362
Query: 339 IGLNSAVIENGKRELSEIIGEIKHGYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVV 398
+ + + +GK +L +II + +G G + +G F + + AYLI++G++V
Sbjct: 363 PRMTNTYMLSGKSKLDDIIKSVDYGIYAVNFSGG-QVDITSGKFVFSTSEAYLIKNGKIV 421
>pir||G70473 tldD homolog - Aquifex aeolicus >gi|2984257|gb|AAC07784.1|
(AE000768) TldD protein [Aquifex aeolicus]
Length = 404
Score = 87.4 bits (213), Expect = 3e-16
Identities = 90/394 (22%), Positives = 158/394 (39%), Gaps = 26/394 (6%)
Query: 12 KYGEKFFDELEIVVRRSRGIEVNVELNEISMGATRIEKVTIIRGIKDKRVGIAIIDTDSK 71
+YGE F++ +SR +++E +I+KVT G D+ VG+ +I
Sbjct: 19 EYGEIFYE-------KSRTTRMHLE-------DRKIDKVT--HGY-DEGVGLRLIKNGKT 61
Query: 72 E---EVKKAIEEAAKMAKLNTPDEKWSSLPSPGKYREK-PKVSEDLKSVSTETLVEFVTR 127
E ++AK+ E + +Y + +V D S + E + R
Sbjct: 62 YYGYTTNPTFENLKELAKILARGEGHGPVAIGKRYIQGYTEVLIDPDKESLKFRAEILRR 121
Query: 128 GIKLARESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKKEGVVTPG 187
+ AR + E+ + N+ G F E V + G
Sbjct: 122 ADEKARSFGDKIKQVLAVLMDKTREIMVINTLGETAEDTQKRVVFFVEVVASDGETLQRG 181
Query: 188 IFDFDAKDNLEL----DVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAISGLLSYAL 243
+ E+ E + + +R + K A TV+ A ++ A+
Sbjct: 182 YESLGGRRGFEIFNETPPEVIAEKAAKRALLMLSAKPAPAGTFTVVMSSQAGGTMIHEAV 241
Query: 244 FPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVTLIE 303
+ + + + A K+GEKVAS+++T+ DD D EGVP ++ LI+
Sbjct: 242 GHGLEADLVQQGLSVYAGKLGEKVASELVTVIDDATLPYHNGSFTVDDEGVPAQRKVLIK 301
Query: 304 EGIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEIIGEIKHG 363
+G+ G+++D A G ESTG+G+R + + + I+ G+ +II + K G
Sbjct: 302 DGVLVGYMYDRLRAMKDGVESTGNGRRQSYAHIPIVRMTNTFIDKGQDNPEDIIKDTKKG 361
Query: 364 YLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEV 397
LV + G N G+F Y+IE+GE+
Sbjct: 362 VLVVKM-GGGEVNTVTGDFVFEVMEGYMIENGEI 394
>sp|P45297|TLDD_HAEIN TLDD PROTEIN HOMOLOG
Length = 482
Score = 85.4 bits (208), Expect = 1e-15
Identities = 85/376 (22%), Positives = 160/376 (41%), Gaps = 28/376 (7%)
Query: 40 ISMGATRIEKVTIIRGIKDKRVGIAIIDTDSKEEVKKAIEEAAKMAKLNTPDEKWSSLPS 99
I G+ I++ +R + ++ G A D + +++ E +A++ K +L S
Sbjct: 54 IKEGSFHIDRGVGVRAVSGEKTGFAYADQINLASLQQCAEAVKGIAQV-----KQGNLIS 108
Query: 100 PGKYREKPKVSE-----DLKSVSTETLVEFVTRGIKLARESDPNVTVAGGSAGTSWAEVE 154
P + ++ L+S++ E +E + + AR D VT S + + EV
Sbjct: 109 PSAFNVVNPIARYAAINPLESLTKEKKIELLHLVDRTARAEDHRVTKVSASLSSVYEEVL 168
Query: 155 IFNSQGINVSQEFGSAHIFFEFVGKKEGVVTPGIFDFDAKDNLELDVEGVVNRGLERVKW 214
I + G + + + ++ G G + L+ E VV+ + V +
Sbjct: 169 IMATDGTLAADIRPLVRLSISVLVEENGKRERGSCGSGGRFGLDWFFE-VVDGDIRAVLF 227
Query: 215 AYNVKEAKNEETTVIFGPWAISGLLSYALFPAFSGERLV-------------KKTTPLAD 261
A KEA + + A +GL+ L + G L K+++
Sbjct: 228 A---KEAVRQALVNLSAVAAPAGLMPVVLGAGWPGVLLHEAVGHGLEGDFNRKESSLFTG 284
Query: 262 KVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVTLIEEGIFKGFIWDNYWAKVYG 321
K+GE+V S + TI DD E D EGVP++ LI++GI +G++ D A++ G
Sbjct: 285 KIGEQVTSPLCTIVDDGTIENRRGSLTIDDEGVPSQCNVLIKDGILQGYMQDKMNARLMG 344
Query: 322 TESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEIIGEIKHGYLVEGLQGAHSSNPDNGN 381
+TG+G+R+ + + + G+ + ++I +K G G + +G
Sbjct: 345 VSTTGNGRRESYAHLPMPRMTNTYMLAGQSQFDDLIASVKQGIYAPHF-GGGQVDITSGK 403
Query: 382 FAVTANPAYLIEDGEV 397
F + + AYLIE G++
Sbjct: 404 FVFSTSEAYLIEKGKI 419
>pir||D72342 tldD protein - Thermotoga maritima (strain MSB8)
>gi|4981251|gb|AAD35808.1|AE001743_10 (AE001743) tldD
protein [Thermotoga maritima]
Length = 499
Score = 85.0 bits (207), Expect = 1e-15
Identities = 69/279 (24%), Positives = 117/279 (41%), Gaps = 12/279 (4%)
Query: 152 EVEIFNSQGINVSQEFGSAHIFFEFVGKKEGVVTPGIFDFDAKDNLE----LDVEGVVNR 207
E+ + NS+G + V +K+GV+ G + A E +DVE +
Sbjct: 189 EILVANSEGTWAEDRRVRTRLMINAVAEKDGVLERGFYGPGAGMGFEFFDRIDVEEAAKK 248
Query: 208 GLERVKWAYNVKEAKNEETTVIFGPWAISGLLSYALFPAFSGERLVKKTTPLADKVGEKV 267
+ A + TV+ + A+ + K + A K+G+KV
Sbjct: 249 AARIAARMVEAEPAPAGKMTVVIANGFGGVIFHEAVGHGLEATSVAKGASVFAGKLGQKV 308
Query: 268 ASDVITIYDDTFHELSIAKAIADGEGVPTRKVTLIEEGIFKGFIWDNYWAKVYGTESTGH 327
A++ ++ DD A D EG PT++ LI++G+ G++ D + G +STG
Sbjct: 309 AAECVSAVDDATIPNGWGSANVDDEGTPTQRTLLIDKGVLVGYLVDKLGERRMGMKSTGS 368
Query: 328 GQRDWRGGGVSIGLNSAVIENGKRELSEIIGEIKHGYLVEGLQGAHSSNPDNGNFAVTAN 387
G+R + +++ I G EII ++G L G S NP G F +
Sbjct: 369 GRRQDYTFPPTSRMSNTFILPGDYHPEEIIAATEYG-LYAKTMGGGSVNPATGEFNFAVS 427
Query: 388 PAYLIEDGEVV----GSTVFLIAGNVYELLKQATEVSKD 422
AYLIE G + G+T + G +E++++ V D
Sbjct: 428 EAYLIEKGRITKPVRGAT---LIGKGHEIIQKIDMVGND 463
>sp|P45077|PMBA_HAEIN PMBA PROTEIN HOMOLOG >gi|1075002|pir||C64186 pmbA protein -
Haemophilus influenzae (strain Rd KW20)
>gi|1574709|gb|AAC22807.1| (U32795) pmbA protein (pmbA)
[Haemophilus influenzae Rd]
Length = 451
Score = 83.9 bits (204), Expect = 3e-15
Identities = 101/442 (22%), Positives = 184/442 (40%), Gaps = 45/442 (10%)
Query: 22 EIVVRRSRGIEVNVELNEISMGATRIEKVTIIRGIKDKRVGIAIIDTDSKEEVKKAIEEA 81
E+ V + G+ V+ L EI + I ++ G A S+ +K A+E A
Sbjct: 37 EVAVTKVSGLSVSARLQEIENVEFTNDGALGISVYMGQQKGNASTSDLSESAIKNAVEAA 96
Query: 82 AKMAKLNTPDEKWSSLPSPGKYREKPKVS-EDLKSVSTETLVEFVTRGIKLARESDPNVT 140
+AK +PD+ + P + + + E + + A ++D +
Sbjct: 97 LAIAKYTSPDDCTGLADKDLMAFDAPDLELYHAADIDVDKATELALQAEQAALQADERII 156
Query: 141 VAGGSAGTSWAEVEIF-NSQGINVSQEFGSAHIFFEFVGKKEGVVTPGIFDFDAKDNLEL 199
+ G++ S V+++ NS G+ S + +G E D LE
Sbjct: 157 NSNGASFNSHTGVKVYGNSHGMLQSYLSSRYSLSCSVIGGVE-------------DALEN 203
Query: 200 DVEGVVNRGLERVK---WA-----------YNVKEAKNEETTVIFGPWAISGLLSYALFP 245
D E ++R ++++ W N ++ E VIF +G++S+
Sbjct: 204 DYEYTISREFDKLQSPIWVGENCAKKVVSRLNPQKLSTREVPVIFLNDVATGIISH-FAA 262
Query: 246 AFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVTLIEEG 305
A SG L +K++ L D +G++V D +I + +A D EGV T+ ++E G
Sbjct: 263 AISGGSLYRKSSFLLDHLGKQVLPDWFSISERPHLLRRLASTPFDSEGVRTQDREIVENG 322
Query: 306 IFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEIIGEIKHGYL 365
I + ++ +Y K G STGH GG+ N V N L+ ++ ++ G L
Sbjct: 323 ILQTYLVTSYSGKKLGMSSTGH------AGGIH---NWLVKPNLTGGLTALLRQMGTGLL 373
Query: 366 VEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVVGSTV-FLIAGNVYELLKQATEVSKDQR 424
V + G N G+++ A+ + +E+GE+ IAG + ++LK V+ D
Sbjct: 374 VTDVMG-QGVNIVTGDYSRGAS-GFWVENGEIQYPVAEITIAGQLQDMLKNMLAVADD-- 429
Query: 425 ALPFMTTAITPYIKFENVKIAG 446
+ + T I + +KI+G
Sbjct: 430 -IEHRSNIQTGSILLDKMKISG 450
>pir||C75180 tldd related protein PAB1955 - Pyrococcus abyssi (strain Orsay)
>gi|5458032|emb|CAB49522.1| (AJ248284) TLDD RELATED
PROTEIN [Pyrococcus abyssi]
Length = 458
Score = 83.9 bits (204), Expect = 3e-15
Identities = 93/368 (25%), Positives = 163/368 (44%), Gaps = 22/368 (5%)
Query: 68 TDSKEEVKKAIEEAAKMAKLNTPDEKWSSLPSPGKYRE---KPKVSEDLKSVSTETLVEF 124
T ++++AI+EA K+AK + +K + K E K K+ + V E V+
Sbjct: 68 TSDLSKLEEAIKEAYKLAKSASETKKEKIELAEIKPVEDFVKSKMKVKPREVDIEEKVKH 127
Query: 125 VTRGIKLARESDP--NVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKKEG 182
+T KL +E + +V + G + + ++G + ++ GKKEG
Sbjct: 128 LTELEKLLKEDETVKSVNIRYEDGG---GQKILLTNEGTRIEWDYNYLWQSVYVTGKKEG 184
Query: 183 VVTP-----GIFDFDAKDNLELDV-EGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAIS 236
+ G D+ + E + E V +R L ++ N K E V+ GP I
Sbjct: 185 KLAMARDSIGAVDYGWELMTEKEPNEKVKDRLLRKLHSQLNGVAPKRGEFPVVAGP-IIV 243
Query: 237 GLLSYALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPT 296
GL+++ + E + +P D +G+++A + +T+ + + E D EGVP
Sbjct: 244 GLIAHEALGHLA-EADLTMNSPFKDLLGKQIAPEYVTM-SERYVEGGFGNDKYDDEGVPV 301
Query: 297 RKVTLIEEGIFKGFIWDNYWAKVYGTESTGHGQ-RDWRGGGVSIGLNSAVIENGKRELSE 355
+ + +IE GI K + + +A + E GH + +D+R + I + + V E G E
Sbjct: 302 KDIHIIENGILKEIMLNREYAAKFNMEPNGHARAQDYRYPPI-IRMRNTVFEPGDWSFEE 360
Query: 356 IIGEIKHGYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVVGS-TVFLIAGNVYELLK 414
+I +IK GY + +G + N F V Y+I +GE+ I G E LK
Sbjct: 361 MIEDIKFGYYLVDFRGGQAQL--NSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALK 418
Query: 415 QATEVSKD 422
+ + V KD
Sbjct: 419 KISAVGKD 426
>pir||S75708 hypothetical protein sll0887 - Synechocystis sp. (strain PCC 6803)
>gi|1001203|dbj|BAA10443.1| (D64003) hypothetical
protein [Synechocystis sp.]
Length = 446
Score = 80.8 bits (196), Expect = 3e-14
Identities = 61/258 (23%), Positives = 122/258 (46%), Gaps = 11/258 (4%)
Query: 193 AKDNLELDVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAISGLLSYALFPAFSGERL 252
++D LD++G + E+ + + + TV+F A LL A ++ + +
Sbjct: 197 SRDLASLDIDGCLQTVKEKTLSHLDYRPIPTGKYTVVFSARAFLSLLG-AFSNLYNAQSI 255
Query: 253 V-KKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVTLIEEGIFKGFI 311
+ K++ + +G +AS+++ + DD H +I+ DGEG PTR+V +I+ G+ G +
Sbjct: 256 LDKQSLATKETLGTAIASELLCVSDDALHPGNISAERFDGEGTPTRRVDIIKNGVLTGLL 315
Query: 312 WDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGK-RELSEIIGEIKHGYLVEGLQ 370
AK + T+ TGH G +++G + + + K E S + + ++ ++ LQ
Sbjct: 316 HSAGTAKRFDTQPTGHAN---IGSKITVGAHFYHVYSEKTAEKSYSLDQAENVVYIDKLQ 372
Query: 371 GAHSS-NPDNGNFAVTANPAYLIEDGEVVGSTVFLIAGNVYELLKQATEVSKDQRALPFM 429
H+ N G+F++ + +L+ GE +AG+ E+LK + + P
Sbjct: 373 ALHAGVNSLQGSFSLPFD-GWLVNKGEKQSIDAATVAGDFLEVLKTIVYLEPEAEVTP-- 429
Query: 430 TTAITPYIKFENVKIAGK 447
+ P + E + I G+
Sbjct: 430 -GGVCPLVWVEGLAITGE 446
>gb|AAC43985.2| (U33883) TldD [Bradyrhizobium japonicum]
Length = 479
Score = 80.8 bits (196), Expect = 3e-14
Identities = 82/356 (23%), Positives = 137/356 (38%), Gaps = 21/356 (5%)
Query: 53 IRGIKDKRVGIAIIDTDSKEEVKKAIEEAAKMAKLNTPDEKWSSLPSPGKYREKPKVSED 112
+R +KD VG A S + I A +A + S P P
Sbjct: 70 LRAVKDDAVGYA---HSSDVSLPALIRAADAVAAVRGGYSGSFSAPPPHTNVRLYGDDNP 126
Query: 113 LKSVSTETLVEFVTRGIKLARESDPNVTVAGGSAGTSWAEVEIFNSQG-----------I 161
L + ET V+ + R+ DP V + G +W VEI G +
Sbjct: 127 LDAPGFETKVKLLAEIDAYLRDKDPRVRQVSVTLGATWQVVEILRPDGESYRDIRPLVRV 186
Query: 162 NVSQEFGSAHIFFEFVGKKEGVVTPGIFDFDAKDNLELDVEGVVNRGLERVKWAYNVKEA 221
N+S G + G K G +F N +G + L ++ ++
Sbjct: 187 NISVVAGQGDR--QESGSKGYGGRAGYAEFIESKNWRDAADGALREALVNLE---SIPAP 241
Query: 222 KNEETTVIFGPWAISGLLSYALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHE 281
E V+ W +L A+ G+ K+T+ A +G +VA+ +T+ DD
Sbjct: 242 AGEMDVVLGAGWP-GVMLHEAVGHGLEGDFNRKRTSAFAGLMGRQVAAKGVTVVDDGTIA 300
Query: 282 LSIAKAIADGEGVPTRKVTLIEEGIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGL 341
D EG PT + LIE+GI G++ D A++ + TG+G+R +
Sbjct: 301 SRRGSLSIDDEGTPTNRTVLIEDGILVGYMQDRQNARLMNMKPTGNGRRQGYAHVPMPRM 360
Query: 342 NSAVIENGKRELSEIIGEIKHGYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEV 397
+ + G R+ +EI+ +K+G G + +G + AY IE+G++
Sbjct: 361 TNTYMLAGDRDPAEILASVKNGVFAANF-GGGQVDITSGKYVFQCTEAYKIENGKI 415
>sp|P74002|YD22_SYNY3 HYPOTHETICAL 53.1 KD PROTEIN SLR1322 >gi|7429840|pir||S75512
hypothetical protein slr1322 - Synechocystis sp. (strain
PCC 6803) >gi|1653157|dbj|BAA18073.1| (D90911)
hypothetical protein [Synechocystis sp.]
Length = 489
Score = 80.0 bits (194), Expect = 5e-14
Identities = 55/206 (26%), Positives = 96/206 (45%), Gaps = 18/206 (8%)
Query: 255 KTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVTLIEEGIFKGFIWDN 314
KTTP DK GEK+A + +T +D+ + + D EG+PT++ LIE GI K FI D
Sbjct: 289 KTTPFLDKKGEKIAHENLTAWDEGLTDNAFGTIDMDDEGMPTQRTLLIENGILKNFIADR 348
Query: 315 YWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEIIGEIKHGYLVEGLQGAHS 374
+ G TG G+R + + + I G + +I ++ G + + G
Sbjct: 349 TGSIRTGHPRTGSGRRQSYAYAAASRMRNTYIAPGNYSVDDIFNSVEKGIYCKQMGGGSV 408
Query: 375 SNPDNGNFAVTANPAYLIEDGEVV----GSTVFLIAGNVYELLKQATEVSKDQRALPFMT 430
NFAV + AYL+E+G++ G+T + G E++ + + S+D
Sbjct: 409 GATGEFNFAV--SEAYLVENGKLTKPLKGAT---LIGTATEIMNKISMSSQDLGLAAGFC 463
Query: 431 TAIT---------PYIKFENVKIAGK 447
+++ P+IK + + + G+
Sbjct: 464 GSVSGSVYVTVGQPHIKVDGITVGGR 489
>pir||F82718 TldD protein XF1127 [imported] - Xylella fastidiosa (strain 9a5c)
>gi|9106089|gb|AAF83937.1|AE003949_1 (AE003949) TldD
protein [Xylella fastidiosa]
Length = 485
Score = 79.6 bits (193), Expect = 7e-14
Identities = 59/199 (29%), Positives = 93/199 (46%), Gaps = 8/199 (4%)
Query: 228 VIFGPWAISGLLSYALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKA 287
V+ G LL A+ G+ K T+ A ++GE+VAS +TI DD +
Sbjct: 253 VVLGAGWPGVLLHEAVGHGLEGDFNRKGTSVYAGRIGERVASPGVTIVDDGTLDGRRGSL 312
Query: 288 IADGEGVPTRKVTLIEEGIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIE 347
D EG PT+ TLIE+G+ G++ D A++ G STG+G+R+ + + +
Sbjct: 313 NIDDEGTPTQCTTLIEDGVLVGYMQDTLNARLMGVASTGNGRRESFAHLTMPRMTNTYMR 372
Query: 348 NGKRELSEIIGEIKHGYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVV----GSTVF 403
G E+I +K G G + +G + +A AYLIEDG V G+T
Sbjct: 373 AGVHSREEMIRSVKKGLYAVNF-GGGQVDITSGKYVFSATEAYLIEDGRVTAPIKGAT-- 429
Query: 404 LIAGNVYELLKQATEVSKD 422
+ GN E +++ + D
Sbjct: 430 -LIGNGPETMQRVRMIGDD 447
>pir||G82325 tldD protein VC0422 [imported] - Vibrio cholerae (group O1 strain
N16961) >gi|9654844|gb|AAF93595.1| (AE004129) tldD
protein [Vibrio cholerae]
Length = 481
Score = 78.0 bits (189), Expect = 2e-13
Identities = 61/199 (30%), Positives = 95/199 (47%), Gaps = 8/199 (4%)
Query: 228 VIFGPWAISGLLSYALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKA 287
V+ G LL A+ G+ K ++ A KVG+KV SD+ TI DD +
Sbjct: 250 VVLGSGWPGVLLHEAVGHGLEGDFNRKGSSVFAGKVGKKVTSDLCTIVDDGTLKDLRGSL 309
Query: 288 IADGEGVPTRKVTLIEEGIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIE 347
D EGV + LIE+GI KG+I D A++ G TG+G+R+ + + +
Sbjct: 310 NVDDEGVSGQYNVLIEKGILKGYIQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYML 369
Query: 348 NGKRELSEIIGEIKHGYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVV----GSTVF 403
G+ EII +K G G + +G F +A+ AYLIE+G++ G+T
Sbjct: 370 PGEHTPEEIIASVKKGIYAPNF-GGGQVDITSGKFVFSASEAYLIENGKITRPIKGAT-- 426
Query: 404 LIAGNVYELLKQATEVSKD 422
+ G+ E ++Q + V D
Sbjct: 427 -LIGSGIEAMQQVSMVGND 444
>sp|P24231|PMBA_ECOLI PMBA PROTEIN (TLDE PROTEIN) >gi|96308|pir||S13730 pmbA protein -
Escherichia coli >gi|42440|emb|CAA38091.1| (X54152) pmbA
is involved in the production of antibiotic MccB17
[Escherichia coli] >gi|537077|gb|AAA97132.1| (U14003)
pmbA gene product [Escherichia coli]
>gi|1732440|dbj|BAA07915.1| (D44452) TldE protein
[Escherichia coli] >gi|1790682|gb|AAC77192.1| (AE000494)
maturation of antibiotic MccB17, see tld genes
[Escherichia coli K12]
Length = 450
Score = 77.3 bits (187), Expect = 3e-13
Identities = 95/425 (22%), Positives = 174/425 (40%), Gaps = 51/425 (12%)
Query: 19 DELEIVVRRSRGIEVNVELNEISMGATRIEKVTIIRGIKDKRVGIAIIDTDSKEEVKKAI 78
D E+ V ++ GI V+ E+ + I R G A S + + + +
Sbjct: 34 DGAEVAVSKTTGISVSTRYGEVENVEFNSDGALGITVYHQNRKGSASSTDLSPQAIARTV 93
Query: 79 EEAAKMAKLNTPDEKWSSLPSPGKYREKPKVSEDLKS--------VSTETLVEFVTRGIK 130
+ A +A+ +PD P G +K ++ D VS + +E R +
Sbjct: 94 QAALDIARYTSPD------PCAG-VADKELLAFDAPDLDLFHPAEVSPDEAIELAARAEQ 146
Query: 131 LARESDPNVTVAGGSAGTSWAEVEIFNS-----QGINVSQEFGSAHIFFEFVGKKEG--- 182
A ++D +T G + S V++F + QG ++ S+ + E G E
Sbjct: 147 AALQADKRITNTEGGSFNSHYGVKVFGNSHGMLQGYCSTRHSLSSCVIAEENGDMERDYA 206
Query: 183 -VVTPGIFDFDAKDNLELDVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAISGLLSY 241
+ + D + + D R L R+ + ++ + VIF +GL +
Sbjct: 207 YTIGRAMSDLQTPEWVGADC---ARRTLSRL----SPRKLSTMKAPVIFANEVATGLFGH 259
Query: 242 ALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVTL 301
L A +G + +K+T L D +G+++ D +TI + +A D EGV T + +
Sbjct: 260 -LVGAIAGGSVYRKSTFLLDSLGKQILPDWLTIEEHPHLLKGLASTPFDSEGVRTERRDI 318
Query: 302 IEEGIFKGFIWDNYWAKVYGTESTGH--GQRDWRGGGVSIGLNSAVIENGK-RELSEIIG 358
I++GI ++ +Y A+ G +STGH G +WR G + + E G ++E++G
Sbjct: 319 IKDGILTQWLLTSYSARKLGLKSTGHAGGIHNWRIAGQGLSFEQMLKEMGTGLVVTELMG 378
Query: 359 EIKHGYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEV-VGSTVFLIAGNVYELLKQAT 417
QG + D A + +E+GE+ + IAGN+ ++ +
Sbjct: 379 -----------QGVSAITGDYSRGAA----GFWVENGEIQYPVSEITIAGNLKDMWRNIV 423
Query: 418 EVSKD 422
V D
Sbjct: 424 TVGND 428
>pir||E71033 tldD-related protein PH1557 - Pyrococcus horikoshii
>gi|3257986|dbj|BAA30669.1| (AP000006) 458aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 458
Score = 76.9 bits (186), Expect = 4e-13
Identities = 90/366 (24%), Positives = 155/366 (41%), Gaps = 18/366 (4%)
Query: 68 TDSKEEVKKAIEEAAKMAKLNTPDEKWSSLPSPGKYRE---KPKVSEDLKSVSTETLVEF 124
T ++V++AI+EA K+AK+ + +K + K E K K+ + V E +
Sbjct: 68 TSELDKVEEAIKEAYKLAKVASETKKEKIKLAEIKPVEDFVKSKMKIKPREVDIEEKINH 127
Query: 125 VTRGIKLARESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKKEGVV 184
+ L +E D V + + ++G + ++ GK++G +
Sbjct: 128 LKELENLLKE-DKAVKSVNIRYEDGGGQKILLTNEGTKIEWDYNYLWQGVYVTGKEDGKL 186
Query: 185 -----TPGIFDFDAKDNLELDV-EGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAISGL 238
T G D+ + E + E V +R L ++ K E V+ GP + +
Sbjct: 187 AMARDTIGAVDYGWELMTEKEPNEKVRDRILRKLHSQLKGITPKRGEFPVVAGPIIVGII 246
Query: 239 LSYALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRK 298
AL E + +P D +G+++A + +T+ + E D EGVP R
Sbjct: 247 AHEAL--GHLAEADLTMNSPFKDLLGKQIAPEYVTM-SERHVEGGFGNDKYDDEGVPVRD 303
Query: 299 VTLIEEGIFKGFIWDNYWAKVYGTESTGHGQ-RDWRGGGVSIGLNSAVIENGKRELSEII 357
+ +IE GI K + + +A + E GH + +D+R + I + + V E G E+I
Sbjct: 304 IHIIENGILKEIMLNREYATKFNMEPNGHARAQDYRYPPI-IRMRNTVFEPGDWSFEEMI 362
Query: 358 GEIKHGYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVVGS-TVFLIAGNVYELLKQA 416
+IK GY + +G + N F V Y+I +GE+ I G E LK+
Sbjct: 363 EDIKFGYYLVDFRGGQAQL--NSAFQVGIQEGYVIRNGEIAEPIRDTSITGVAIEALKKI 420
Query: 417 TEVSKD 422
T V KD
Sbjct: 421 TAVGKD 426
>pir||A75213 tldd protein PAB0154 - Pyrococcus abyssi (strain Orsay)
>gi|5457661|emb|CAB49152.1| (AJ248283) TLDD PROTEIN
[Pyrococcus abyssi]
Length = 452
Score = 76.9 bits (186), Expect = 4e-13
Identities = 92/426 (21%), Positives = 175/426 (40%), Gaps = 19/426 (4%)
Query: 7 MEELIKYGEKFFDELEIVVRRSRGI---EVNVELNEISMGATRIEKVTIIRGIKDKRVGI 63
++EL EK+ +E++ + R E VE ++ G E+V I G++ G
Sbjct: 2 IDELRNLIEKYSNEVKFMDIRFENTIYTEFTVENGKVE-GVESNEEVGI--GVRVLINGW 58
Query: 64 AIIDTDSKEEVKKAIEEAAKMAKLNTPDEK-WSSLPSPGKYREKPKVSEDLKSVSTETLV 122
T+ +++ I+ A K+AK++ + + P GK K K +D V E
Sbjct: 59 GFASTNDLSKLEDTIKMAIKLAKVSNAEVPLYVGNPVEGKAIIKQK--KDFLDVDLEEKT 116
Query: 123 EFVTRGIKLARESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKKEG 182
+ K+ R + + S NS+G + + V +
Sbjct: 117 KLGLEVEKMIRRD--KIKTSRFSYSDFVTRKIYLNSEGSVIETVVPRIYFSLSAVARSAD 174
Query: 183 VVTPGIFDFDAKDNLELDVEGV-----VNRGLERVKWAYNVKEAKNEETTVIFGPWAISG 237
++ F EL VE V N + + + + E +I P
Sbjct: 175 IMQTYWKSFGGTVGWEL-VESVDFNYWANFISSKALSLLSARSPPSGEMPIIMDPELAGV 233
Query: 238 LLSYALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTR 297
+ AL A + + + + L+ +G+K+ S+ +T+ DD + D EG+P +
Sbjct: 234 FIHEALGHAVEADSVRQGESILSGMIGKKIGSEELTVIDDPTLPGKFGSYVYDDEGLPGK 293
Query: 298 KVTLIEEGIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEII 357
+V +I++G+ ++ D +K GHG+ + +++ I G+ L E+
Sbjct: 294 RVEIIKDGVLLNYLNDRETSKALNLVPNGHGRAQSYAHVPLVRMSNTYIAPGEWTLEEMF 353
Query: 358 GEIKHGYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVVGSTVFL-IAGNVYELLKQA 416
E+K G + G +G + NG+F A Y+I++GE+ + I+GN+ + LK+
Sbjct: 354 EEVKFGVYMIGDKGG-QVDIANGSFMFGAKEGYIIKEGEIKEQVRDVGISGNILDTLKEI 412
Query: 417 TEVSKD 422
V +D
Sbjct: 413 KAVGRD 418
>emb|CAC11943.1| (AL445065) conserved hypothetical protein [Thermoplasma
acidophilum]
Length = 430
Score = 76.5 bits (185), Expect = 6e-13
Identities = 92/441 (20%), Positives = 179/441 (39%), Gaps = 33/441 (7%)
Query: 6 EMEELIKYGEKFFDELEIVVRRSRGIEVNVELNEISMGATRIEKVTIIRGIKDKRVGIAI 65
+M+ + + EK FDE I + +R +V + E V ++ + KR +
Sbjct: 5 DMDRISESFEKRFDEYAIEMHVNRDDQVRFSNGSRDLHNIWEESVLLVFVARGKRTLMTT 64
Query: 66 IDTDSKEEVKKAIEEAAKMAKLNTPDEKWSSLPSPGK-YREKPKVSEDLKSVSTETLVEF 124
I + +++++IE+ ++ + +S + + YR K+ + + L +
Sbjct: 65 IKEGA--DLERSIEDLSRRIDQTPENPLFSGINDRKQVYR---KLDLPPREFDADELADM 119
Query: 125 VTRGIKLARESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKKEGVV 184
G + D G + + VEI G+ + F G + G
Sbjct: 120 AMAGSR-----DAGSERMAGLVYSMRSRVEIATRYNRGSYDSIGAEVVVRSFRGDRSGQE 174
Query: 185 T--PGIFDFDAKDNLELDVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAISGLLSYA 242
GI N LD + R E + A E + VI P A +++
Sbjct: 175 CGHTGI-------NGYLDAYAIGKRSAESIVNAER-HEGREGHYDVILAPMAAGNIITSG 226
Query: 243 LFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVTLI 302
+ AFS ++ + L D +G ++A+ ++ +YDD +A + D EG T +V +I
Sbjct: 227 SY-AFSAHTVISGLSFLQDSMGRQIAAPMVNLYDDPTDTAGMAYRVFDEEGTATSRVPII 285
Query: 303 EEGIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEIIGEIKH 362
E G+ ++ A+ TE+TG+ G +S ++ G E+I + +
Sbjct: 286 EHGVLNTYLHSTSTARYMNTETTGN------AGIISPEAWQLEMDGGDASAEELISDTRE 339
Query: 363 GYLVEGLQGAHSSNPDNGNFA-VTANPAYLIEDGEVVGS-TVFLIAGNVYELLKQATEVS 420
G + + NG F+ V + Y I +GE+ + I+ ++ E+LK+ + +S
Sbjct: 340 GVFIRNSWYLRFQDYRNGVFSTVPRDGVYYIRNGEIAEAWDGIRISDSIPEILKKISALS 399
Query: 421 KDQRALPFMTTAI---TPYIK 438
K+ + + + + PYIK
Sbjct: 400 KETQYVKWWNEVMPSRLPYIK 420
>pir||D83086 conserved hypothetical protein PA4474 [imported] - Pseudomonas
aeruginosa (strain PAO1)
>gi|9950711|gb|AAG07862.1|AE004861_3 (AE004861)
conserved hypothetical protein [Pseudomonas aeruginosa]
Length = 480
Score = 75.3 bits (182), Expect = 1e-12
Identities = 92/396 (23%), Positives = 160/396 (40%), Gaps = 23/396 (5%)
Query: 40 ISMGATRIEKVTIIRGIKDKRVGIAIIDTDSKEEVKKAIEEAAKMAKL--NTPDEKWSSL 97
+ G+ +++ +R ++ G A + + E +K+A A +++ N + + ++
Sbjct: 57 VKEGSFNLDQGVGVRAQSGEKTGFAYSNAITAEALKQAAVAARSISRAGQNGSVQAFKAV 116
Query: 98 PSPGKYR-EKPKVSEDLKSVSTETLVEFVTRGIKLARESDPNVTVAGGSAGTSWAEVEIF 156
Y E P L +S VE + + R DP + S W ++ +
Sbjct: 117 VPARLYAGENP-----LDVLSRAEKVELLKQIDAATRALDPRIQQVTVSMAGVWEQILVA 171
Query: 157 NSQG-----INVSQEFGSAHIFFEFVGKKEGVVTPGIFDFDAKDNLELD-VEGVVNRGLE 210
S G I F + + E G++E G D + L+ D G L
Sbjct: 172 ASDGSLAADIRPLVRF-NVSVIVEQNGRRERGGHGGGGRTDYRYFLQEDRAMGYAREALR 230
Query: 211 RVKWAYNVKEAKNEETTVIFGPWAISGLLSYALFPAFSGERLVKKTTPLADKVGEKVASD 270
+ A V+ G LL A+ G+ K ++ + +VGEKVAS
Sbjct: 231 QALVNLEAIPAPAGTLPVVMGAGWSGVLLHEAVGHGLEGDFNRKGSSAYSGRVGEKVASS 290
Query: 271 VITIYDDTFHELSIAKAIADGEGVPTRKVTLIEEGIFKGFIWDNYWAKVYGTESTGHGQR 330
+ TI DD D EG P+ LIE G+ KG++ D A++ G TG+G+R
Sbjct: 291 LCTIVDDGTLAGRRGSLSVDDEGTPSNCNVLIENGVLKGYMQDKLNARLMGVARTGNGRR 350
Query: 331 DWRGGGVSIGLNSAVIENGKRELSEIIGEIKHGYLVEGLQGAHSSNPDNGNFAVTANPAY 390
+ + + + G+ + EII ++ G L G + +G F + + AY
Sbjct: 351 ESYAHLPMPRMTNTYMLAGESDPQEIIASVEKGIYCANL-GGGQVDITSGKFVFSTSEAY 409
Query: 391 LIEDGEVV----GSTVFLIAGNVYELLKQATEVSKD 422
LIE+G + G+T + GN E + + + V D
Sbjct: 410 LIENGRITTPVKGAT---LIGNGPEAMSRVSMVGND 442
>pir||B82719 PmbA protein XF1131 [imported] - Xylella fastidiosa (strain 9a5c)
>gi|9106093|gb|AAF83941.1|AE003949_5 (AE003949) PmbA
protein [Xylella fastidiosa]
Length = 428
Score = 71.8 bits (173), Expect = 1e-11
Identities = 102/423 (24%), Positives = 170/423 (40%), Gaps = 49/423 (11%)
Query: 20 ELEIVVRRSRGIEVNVELNEISMGATRIEKVTIIRGIKDKRVGIAIIDTDSKEEVKKAIE 79
+ E+ RG++VNV + ++ + ++ + R G A + ++ +
Sbjct: 12 QAEVGCSEERGLDVNVRMGDVETVESTCDRSIGVTLYFGHRKGCASTADLQEASLEATVA 71
Query: 80 EAAKMAKLNTPDEKWSSLPSPGKYREKPKVSEDLKSVSTETLVEFVTRGIKLARESDPNV 139
+A +A+ T D+ + L P + V DL TL + LA E
Sbjct: 72 QACAIARY-TEDDPANGLADPVRMAT---VFPDLDCWHPWTLEAGAAVDLALACE----- 122
Query: 140 TVAGGSAGTSWAEVEIFNSQGINVSQEFG-----SAHIFFE-------------FVGKKE 181
A G A A+ I NS G +VS F ++H F G +
Sbjct: 123 --AAGRA----ADARIVNSDGASVSTRFALSVYANSHGFVGRERMTQHSMSCALIAGHGD 176
Query: 182 GVVTPGIF-DFDAKDNLELDVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAISGLLS 240
G+ G + + A+++LEL V V + ER + + V+F P L+
Sbjct: 177 GMQRDGWYTNALAREDLELPV-AVGRKAAERTVARLQPRSLATTQLPVLFVPEVARSLIG 235
Query: 241 YALFPAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVT 300
+ L A SG L ++ + L D VG ++ + I + + A D EGV T
Sbjct: 236 H-LLNAVSGGALYRRASFLLDSVGTRLFPEWFAINERPHLRRGLRSATFDAEGVVTCDAP 294
Query: 301 LIEEGIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEIIGEI 360
L+ G+ + ++ +Y A+ G +ST + GGV N VI N L ++ +
Sbjct: 295 LVAGGVLQRYVLSSYSARKLGLQSTAN------AGGVH---NLEVIANA-AGLDALVAGL 344
Query: 361 KHGYLVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEVVGSTVFL-IAGNVYELLKQATEV 419
G LV L G+ NP G+++ A + IE+G + L IAGN+ E+ V
Sbjct: 345 PRGLLVTELMGS-GVNPVTGDYSRGA-AGFWIENGAIAYPVDGLTIAGNLREMFSAIEAV 402
Query: 420 SKD 422
D
Sbjct: 403 GAD 405
>pir||D82066 pmbA protein VC2535 [imported] - Vibrio cholerae (group O1 strain
N16961) >gi|9657118|gb|AAF95676.1| (AE004322) pmbA
protein [Vibrio cholerae]
Length = 447
Score = 71.4 bits (172), Expect = 2e-11
Identities = 92/444 (20%), Positives = 186/444 (41%), Gaps = 41/444 (9%)
Query: 19 DELEIVVRRSRGIEVNV---ELNEISMGATRIEKVTIIRGIKDKRVGIAIIDTDSKEEVK 75
D E+ + +S G+ V+ E+ + + +T+ RG +R G A S++ ++
Sbjct: 30 DAAEVAITKSTGLSVSTRMCEVENVEFNSDGALGITVYRG---QRKGSASTSDLSEKAIR 86
Query: 76 KAIEEAAKMAKLNTPDEKWSSLPSPGKYREKPKVS-----EDLKSVSTETLVEFVTRGI- 129
+ + A +A+ + D P +E P + E V+ + + +
Sbjct: 87 QTVLAALDIAQYTSADPYAGPAPKELMVQEIPDLDLFHPDEPNPDVAAQIAIAAERAALG 146
Query: 130 --KLARESDPNVTVAGGSAGTSWAEVEIFNSQGINVSQEFGSAHIFFEFVGKKEGVVTPG 187
K ++SD GGS + + NS G+ S I +G+
Sbjct: 147 YSKKIKQSD------GGSYDSHYGVRVYGNSHGLLASYASSRHSISCSVIGEGRNGEMER 200
Query: 188 IFDFDA---KDNLELDVEGVVNRGLERVKWAYNVKEAKNEETTVIFGPWAISGLLSYALF 244
+ + +D+L E V + E + ++ K + V+F +GL+ + L
Sbjct: 201 DYSYTVARHRDDLWTP-ESVGLQAAENTVSRLDPQKLKTGQFPVMFAADVATGLIGH-LV 258
Query: 245 PAFSGERLVKKTTPLADKVGEKVASDVITIYDDTFHELSIAKAIADGEGVPTRKVTLIEE 304
A SG L +K++ L D +G+ + I + +A + D EGV T+ + +I +
Sbjct: 259 MAISGGNLYRKSSFLLDHLGKTILPTWFNISERPHVMRGLASSPFDSEGVRTQDLEIITD 318
Query: 305 GIFKGFIWDNYWAKVYGTESTGHGQRDWRGGGVSIGLNSAVIENGKRELSEIIGEIKHGY 364
G+ ++ +Y A+ TGH G+++ +++ + +++ E+ G
Sbjct: 319 GVLATYLLTSYAARKMNMTPTGHAG----------GIHNWYVKSTGQNYQQMLKELGTGL 368
Query: 365 LVEGLQGAHSSNPDNGNFAVTANPAYLIEDGEV-VGSTVFLIAGNVYELLKQATEVSKDQ 423
LV + G N G+++ A + +E+GE+ + IAGN+ ++L+Q V D
Sbjct: 369 LVTEVMG-QGVNVVTGDYSRGA-AGFWVENGEIKYPVSEITIAGNLKQMLQQIVAVGSD- 425
Query: 424 RALPFMTTAITPYIKFENVKIAGK 447
+ + T I E++K+AG+
Sbjct: 426 --IETRSQIQTGSILIESMKVAGE 447
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.314 0.135 0.380
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 168650863
Number of Sequences: 2977
Number of extensions: 7400631
Number of successful extensions: 15131
Number of sequences better than 1.0e-10: 39
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 15072
Number of HSP's gapped (non-prelim): 39
length of query: 448
length of database: 189,106,746
effective HSP length: 60
effective length of query: 388
effective length of database: 153,197,526
effective search space: 59440640088
effective search space used: 59440640088
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 42 (21.9 bits)
S2: 166 (69.1 bits)