BLASTP 2.0.10 [Aug-26-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= PAB1968 (mutT) DE:mutator protein MutT (mutT)
(173 letters)
Database: ./suso.pep; /banques/blast2/nr.pep
598,487 sequences; 189,106,746 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
pir||B75178 mutator protein mutt (mutt) PAB1968 - Pyrococcus aby... 346 1e-94
pir||C71036 hypothetical protein PH1579 - Pyrococcus horikoshii ... 280 6e-75
gi|11498833 mutator protein MutT (mutT) [Archaeoglobus fulgidus]... 148 4e-35
pir||G69041 mutator MutT protein - Methanobacterium thermoautotr... 139 2e-32
sp|Q58549|ADPP_METJA ADP-RIBOSE PYROPHOSPHATASE (ADP-RIBOSE DIPH... 138 4e-32
pir||A70426 8-OXO-dGTPase domain (mutT domain) - Aquifex aeolicu... 127 1e-28
pir||S75733 hypothetical protein slr0920 - Synechocystis sp. (st... 109 2e-23
gb|AAF73820.1| (AF154044) unknown [Streptococcus pneumoniae] >gi... 90 2e-17
pir||S77438 hypothetical protein slr1134 - Synechocystis sp. (st... 83 2e-15
pir||T36870 probable DNA hydrolase - Streptomyces coelicolor >gi... 80 1e-14
pir||T35191 probable DNA hydrolase - Streptomyces coelicolor >gi... 80 2e-14
emb|CAC12694.1| (AJ272115) hypothetical protein [Thauera aromatica] 78 6e-14
sp|Q55928|NADM_SYNY3 BIFUNCTIONAL NMN ADENYLYLTRANSFERASE/NUDIX ... 76 3e-13
gb|AAK42441.1| MutT-like protein [Sulfolobus solfataricus] 72 3e-12
>pir||B75178 mutator protein mutt (mutt) PAB1968 - Pyrococcus abyssi (strain
Orsay) >gi|5458015|emb|CAB49505.1| (AJ248284) mutator
protein MutT (mutT) [Pyrococcus abyssi]
Length = 173
Score = 346 bits (878), Expect = 1e-94
Identities = 173/173 (100%), Positives = 173/173 (100%)
Query: 1 MVKMDRYVLLIKAPKGYDVSEFREEVRKIAEGKRLRAELHRCIGLTVDLVIVYNNGIVFI 60
MVKMDRYVLLIKAPKGYDVSEFREEVRKIAEGKRLRAELHRCIGLTVDLVIVYNNGIVFI
Sbjct: 1 MVKMDRYVLLIKAPKGYDVSEFREEVRKIAEGKRLRAELHRCIGLTVDLVIVYNNGIVFI 60
Query: 61 RRKNEPYKGYLALPGGFVEYGERVEEAAVREAKEETGLDVKLLRIVGVYSDPNRDPRGHT 120
RRKNEPYKGYLALPGGFVEYGERVEEAAVREAKEETGLDVKLLRIVGVYSDPNRDPRGHT
Sbjct: 61 RRKNEPYKGYLALPGGFVEYGERVEEAAVREAKEETGLDVKLLRIVGVYSDPNRDPRGHT 120
Query: 121 VTIAFLAVGSGELKAGDDAKDVTVIPIEKIEEVKDKLAFDHAKIVEDALKLRC 173
VTIAFLAVGSGELKAGDDAKDVTVIPIEKIEEVKDKLAFDHAKIVEDALKLRC
Sbjct: 121 VTIAFLAVGSGELKAGDDAKDVTVIPIEKIEEVKDKLAFDHAKIVEDALKLRC 173
>pir||C71036 hypothetical protein PH1579 - Pyrococcus horikoshii
>gi|3258008|dbj|BAA30691.1| (AP000006) 173aa long
hypothetical protein [Pyrococcus horikoshii]
Length = 173
Score = 280 bits (709), Expect = 6e-75
Identities = 130/172 (75%), Positives = 156/172 (90%)
Query: 1 MVKMDRYVLLIKAPKGYDVSEFREEVRKIAEGKRLRAELHRCIGLTVDLVIVYNNGIVFI 60
M+KM RY LLIKAP YD+S F +++++ + + ++ E++RCIGLTVD+VI+YNNGIV I
Sbjct: 1 MIKMKRYALLIKAPDDYDISGFEKKIKETGKKEGIKVEMYRCIGLTVDIVIIYNNGIVLI 60
Query: 61 RRKNEPYKGYLALPGGFVEYGERVEEAAVREAKEETGLDVKLLRIVGVYSDPNRDPRGHT 120
RRKNEPYKG+LALPGGFVEYGE+VE+AA+REAKEETGLDVKLLRIVGVYSDP RDPRGHT
Sbjct: 61 RRKNEPYKGFLALPGGFVEYGEKVEDAAIREAKEETGLDVKLLRIVGVYSDPRRDPRGHT 120
Query: 121 VTIAFLAVGSGELKAGDDAKDVTVIPIEKIEEVKDKLAFDHAKIVEDALKLR 172
VT+AFLAVGSGELKAGDDAKDVTV+PI +IE +K+KLAFDHAKI+EDAL L+
Sbjct: 121 VTVAFLAVGSGELKAGDDAKDVTVVPINEIERIKEKLAFDHAKIIEDALTLK 172
>gi|11498833 mutator protein MutT (mutT) [Archaeoglobus fulgidus]
>gi|7451650|pir||A69404 mutator protein MutT (mutT)
homolog - Archaeoglobus fulgidus
>gi|2649348|gb|AAB90010.1| (AE001019) mutator protein
MutT (mutT) [Archaeoglobus fulgidus]
Length = 137
Score = 148 bits (370), Expect = 4e-35
Identities = 73/129 (56%), Positives = 96/129 (73%), Gaps = 5/129 (3%)
Query: 41 RCIGLTVDLVIVYNNGIVFIRRKNEPYKGYLALPGGFVEYGERVEEAAVREAKEETGLDV 100
+CI LTVD +I Y IV I+R NEP+KG+ ALPGG VEYGERVE+A +RE +EETGL
Sbjct: 2 KCITLTVDAIIPYQGKIVLIKRLNEPFKGHYALPGGIVEYGERVEDAVLREVEEETGLKG 61
Query: 101 KLLRIVGVYSDPNRDPRGHTVTIAFLAV-GSGELKAGDDAKDVTVIPIEKIEEVKDKLAF 159
++ +VGVYSDPNRDPRGH V++ F+ + GELKAG DAK+V + + ++ KLAF
Sbjct: 62 EIHSLVGVYSDPNRDPRGHFVSVCFVVLPKGGELKAGSDAKEVGLFSLNEL----PKLAF 117
Query: 160 DHAKIVEDA 168
DH K+++DA
Sbjct: 118 DHEKMIKDA 126
>pir||G69041 mutator MutT protein - Methanobacterium thermoautotrophicum
(strain Delta H) >gi|2622420|gb|AAB85793.1| (AE000895)
mutator MutT protein [Methanobacterium
thermoautotrophicum]
Length = 135
Score = 139 bits (347), Expect = 2e-32
Identities = 73/125 (58%), Positives = 95/125 (75%), Gaps = 4/125 (3%)
Query: 45 LTVDLVI-VYNNGIVFIRRKNEPYKGYLALPGGFVEYGERVEEAAVREAKEETGLDVKLL 103
LTVD++I + + I+ IRR PY+G A+PGGFVEYGE VE+AA REA EETGLDV++
Sbjct: 6 LTVDVIIRLSGDRIILIRRGRSPYRGSWAIPGGFVEYGETVEDAARREALEETGLDVEIK 65
Query: 104 RIVGVYSDPNRDPRGHTVTIAFLA-VGSGELKAGDDAKDVTVIPIEKIEEVKDKLAFDHA 162
++GVYSDP RDPRGHTV++ F A V SGE +AG DA D+ + IE I+++ +LAFDH
Sbjct: 66 DLLGVYSDPRRDPRGHTVSVCFTARVVSGEPEAGSDAADIGIFHIEDIDDL--ELAFDHR 123
Query: 163 KIVED 167
KI+ED
Sbjct: 124 KILED 128
>sp|Q58549|ADPP_METJA ADP-RIBOSE PYROPHOSPHATASE (ADP-RIBOSE DIPHOSPHATASE) (ADENOSINE
DIPHOSPHORIBOSE PYROPHOSPHATASE) (ADPR-PPASE)
(ADP-RIBOSE PHOSPHOHYDROLASE) >gi|2129134|pir||D64443
mutator protein mutT - Methanococcus jannaschii
>gi|1500003|gb|AAB99149.1| (U67557) mutator MutT
protein, putative (mutT) [Methanococcus jannaschii]
Length = 169
Score = 138 bits (344), Expect = 4e-32
Identities = 75/150 (50%), Positives = 100/150 (66%), Gaps = 7/150 (4%)
Query: 22 FREEVRKIAEGKRLRAELHRCIGLTVDLVIVYNNGIVFIRRKNEPYKGYLALPGGFVEYG 81
+ +++ K + K+ R LH + VD +I +N I+ I+RKN P+KG ALPGGFVE G
Sbjct: 22 YSKKIIKKRDLKKYRLYLHPAVA--VDGIIEKDNKILLIKRKNNPFKGCFALPGGFVECG 79
Query: 82 ERVEEAAVREAKEETGLDVKLLRIVGVYSDPNRDPRGHTVTIAF-LAVGSGELKAGDDAK 140
E VEEA VRE KEETGL K+ ++GVYS P+RDPRGH ++I F L V GELKAGDDAK
Sbjct: 80 ETVEEAVVREIKEETGLIPKVKSLLGVYSSPDRDPRGHVISIVFILDVIGGELKAGDDAK 139
Query: 141 DVTVIPIEKIEEVKDKLAFDHAKIVEDALK 170
+ + + KLAFDH KI++D ++
Sbjct: 140 EAEFFDLNNL----PKLAFDHEKIIKDYMR 165
>pir||A70426 8-OXO-dGTPase domain (mutT domain) - Aquifex aeolicus
>gi|2983843|gb|AAC07397.1| (AE000741) 8-OXO-dGTPase
domain (mutT domain) [Aquifex aeolicus]
Length = 139
Score = 127 bits (315), Expect = 1e-28
Identities = 68/115 (59%), Positives = 81/115 (70%), Gaps = 4/115 (3%)
Query: 56 GIVFIRRKNEPYKGYLALPGGFVEYGERVEEAAVREAKEETGLDVKLLRIVGVYSDPNRD 115
GIV I RK P LALPGGFVE GERVEEAA RE +EETGL+V+L +++GVYSDP RD
Sbjct: 26 GIVLIERKYPPVG--LALPGGFVEVGERVEEAAAREMREETGLEVRLHKLMGVYSDPERD 83
Query: 116 PRGHTVTIAFLAVGSGELKAGDDAKDVTVIPIEKIEEVKDKLAFDHAKIVEDALK 170
PR H V++ ++ GE KAG DAK V V +E+I DKL FDH KI+ D LK
Sbjct: 84 PRAHVVSVVWIGDAQGEPKAGSDAKKVKVYRLEEIP--LDKLVFDHKKIILDFLK 136
>pir||S75733 hypothetical protein slr0920 - Synechocystis sp. (strain PCC 6803)
>gi|1001228|dbj|BAA10468.1| (D64003) hypothetical
protein [Synechocystis sp.]
Length = 149
Score = 109 bits (270), Expect = 2e-23
Identities = 62/131 (47%), Positives = 84/131 (63%), Gaps = 9/131 (6%)
Query: 46 TVDLVIVY----NNGIVFIRRKNEPYKGYLALPGGFVEYGERVEEAAVREAKEETGLDVK 101
TVDL+I I+ I R+N P+ G+ ALPGGFV+YGE +E AA+REAKEE LDV+
Sbjct: 9 TVDLIIEMIDQPRRPILLIERQNPPH-GW-ALPGGFVDYGETLEAAALREAKEEISLDVQ 66
Query: 102 LLRIVGVYSDPNRDPRGHTVTIAFLAVGSGELKAGDDAKDVTVIPIEKIEEVKDKLAFDH 161
L+ + YSDP RDPR HT+++ FLA +G+ +A DDAK V + E D + FDH
Sbjct: 67 LIEMFYAYSDPRRDPRQHTLSVVFLAAATGKPQAADDAKTVGFF---DLWEFPDPVCFDH 123
Query: 162 AKIVEDALKLR 172
+I+ D + R
Sbjct: 124 GQILRDYRRYR 134
>gb|AAF73820.1| (AF154044) unknown [Streptococcus pneumoniae]
>gi|8163725|gb|AAF73827.1| (AF154045) unknown
[Streptococcus pneumoniae]
Length = 212
Score = 89.7 bits (219), Expect = 2e-17
Identities = 54/129 (41%), Positives = 73/129 (55%), Gaps = 15/129 (11%)
Query: 57 IVFIRRKNEPYKGYLALPGGFVEYGERVEEAAVREAKEETGLDVKLLRI--VGVYSDPNR 114
++ IRRK PY+ YLAL GGF++ GE A RE KEE LD+ L +I + S P R
Sbjct: 13 LLLIRRKAHPYQNYLALVGGFMDKGEDAAHACQREVKEEVNLDLPLEKIEQLMTVSTPGR 72
Query: 115 DPRGHTVTIAFLAVGSGE----LKAGDDAKDVTVIPI---------EKIEEVKDKLAFDH 161
DPRG TVTIA+L ++A DDAKDV + + E +E + LAFDH
Sbjct: 73 DPRGWTVTIAYLVYLPSRALELVQASDDAKDVVFVDVDFQTGKCYLEGVELDEQALAFDH 132
Query: 162 AKIVEDALK 170
I++ ++K
Sbjct: 133 YAIIQKSIK 141
>pir||S77438 hypothetical protein slr1134 - Synechocystis sp. (strain PCC 6803)
>gi|1652363|dbj|BAA17285.1| (D90905) hypothetical
protein [Synechocystis sp.]
Length = 148
Score = 82.7 bits (201), Expect = 2e-15
Identities = 46/134 (34%), Positives = 83/134 (61%), Gaps = 6/134 (4%)
Query: 39 LHRCIGLTVDLVIVYNNGIVFIRRKNEPYKGYLALPGGFVEYGERVEEAAVREAKEETGL 98
L R + + ++ ++ IV ++R++ G +LPGG +++GE V A RE +EETGL
Sbjct: 13 LRRPLSAVTVIPVLSDSSIVLVKRRDT---GQWSLPGGLIDWGETVAITAARELQEETGL 69
Query: 99 D-VKLLRIVGVYSDPNRDPRGHTVTIAFLAVGSGELKAGDDAKDVTVIPIEKIEEVK-DK 156
+K+ R++GVYS P+RDPR H+VTI+ + G+L G D ++++ + +E++
Sbjct: 70 RLIKIDRLLGVYSSPDRDPRMHSVTISLVVKAQGDLLIG-DRQEISEVKAFAVEDLPLGA 128
Query: 157 LAFDHAKIVEDALK 170
L+ DH + ++D L+
Sbjct: 129 LSHDHDQQLQDFLR 142
>pir||T36870 probable DNA hydrolase - Streptomyces coelicolor
>gi|5738483|emb|CAB52831.1| (AL109848) putative DNA
hydrolase [Streptomyces coelicolor A3(2)]
Length = 239
Score = 80.4 bits (195), Expect = 1e-14
Identities = 55/133 (41%), Positives = 73/133 (54%), Gaps = 13/133 (9%)
Query: 45 LTVDLVIVYNNG----IVFIRRKNEPYKGYLALPGGFVEYGERVEEAAVREAKEETGL-D 99
+TVDL ++ + + R EPY G ALPGGF+ E EEAA RE EETGL D
Sbjct: 14 VTVDLAVLTLRAGALHALLVERGQEPYAGRWALPGGFLLPAESAEEAARRELAEETGLAD 73
Query: 100 VKLLRI--VGVYSDPNRDPRGHTVTIAFLAV--GSGELKAGDDAKDVTVIPIEKIEEVKD 155
V L + + YS+P RDPR V++AF A+ E G DA + +P +K +
Sbjct: 74 VTGLHLEQLRTYSEPGRDPRMRVVSVAFAALLPDPPEPHGGGDAAEARWVPYDKAQ---- 129
Query: 156 KLAFDHAKIVEDA 168
LAFDH +I+ DA
Sbjct: 130 GLAFDHDRILADA 142
>pir||T35191 probable DNA hydrolase - Streptomyces coelicolor
>gi|3036882|emb|CAA18515.1| (AL022374) SC5B8.07,
possible DNA hydrolase with mutT domain, l en: 294 aa;
similar in part to many hypothetical proteins e .g
Synechocystis sp. TR:P74291 (EMBL:D90913) (261 aa), fast
a scores; opt: 241 z-score: 358.0 E(): 9.6e-13, 34.7%
ident ity in 2>
Length = 294
Score = 79.6 bits (193), Expect = 2e-14
Identities = 55/152 (36%), Positives = 79/152 (51%), Gaps = 26/152 (17%)
Query: 45 LTVDLVIV----YNNGIVFIRRKNEPYKGYLALPGGFVEYGERVEEAAVREAKEETGLDV 100
+TVDLV++ ++ + +RR P++G ALPGGFV GE + +AA RE EETGL V
Sbjct: 55 VTVDLVVLTVRRHSLCALAVRRGEPPFQGRWALPGGFVRDGEDLAQAAARELAEETGLCV 114
Query: 101 -----------KLLRIVGVYSDPNRDPRGHTVTIAFLAVGSG--ELKAGDDAKDVTVIPI 147
L + Y DP RDPR V++A LA+ +AG DA + P+
Sbjct: 115 HDPAAPSQDNGAHLEQLATYGDPERDPRMRVVSVAHLALAPDLPAPRAGGDASNARWAPV 174
Query: 148 EKI---------EEVKDKLAFDHAKIVEDALK 170
E++ E LAFDHA+I+ D ++
Sbjct: 175 EELLEQSGYGRAGEAVAPLAFDHAQILADGVE 206
>emb|CAC12694.1| (AJ272115) hypothetical protein [Thauera aromatica]
Length = 182
Score = 78.0 bits (189), Expect = 6e-14
Identities = 44/96 (45%), Positives = 62/96 (63%), Gaps = 3/96 (3%)
Query: 50 VIVYNNGIVFIRRKNEPYKGYLALPGGFVEYGERVEEAAVREAKEETGLDVKLLRIVGVY 109
VI + +V IRRK +P GY A PGG+VE GE +EEA VREA+EE+GL+V + ++GVY
Sbjct: 44 VIEHAGQLVLIRRKLDPLAGYWAPPGGYVERGESLEEAVVREAREESGLEVAVDELIGVY 103
Query: 110 SDPNRDPRGHTVTIAFLAVGSGELKAGDDAKDVTVI 145
S D R + ++G GE AGDDA ++ ++
Sbjct: 104 S--QADVRAVILAYRAHSIG-GEPVAGDDAGEICLV 136
>sp|Q55928|NADM_SYNY3 BIFUNCTIONAL NMN ADENYLYLTRANSFERASE/NUDIX HYDROLASE [CONTAINS:
NICOTINAMIDE-NUCLEOTIDE ADENYLYLTRANSFERASE (NAD(+)
PYROPHOSPHORYLASE) (NAD(+) DIPHOSPHORYLASE) (NMN
ADENYLYLTRANSFERASE); ADP COMPOUNDS HYDROLASE ]
>gi|7446147|pir||S77001 hypothetical protein slr0787 -
Synechocystis sp. (strain PCC 6803)
>gi|1001812|dbj|BAA10693.1| (D64005) hypothetical
protein [Synechocystis sp.]
Length = 339
Score = 75.7 bits (183), Expect = 3e-13
Identities = 46/132 (34%), Positives = 74/132 (55%), Gaps = 10/132 (7%)
Query: 45 LTVDLVIVYNNGIVFIRRKNEPYKGYLALPGGFVEYGERVEEAAVREAKEETGLDVKLLR 104
+T D V+V ++ +RR+ +P G +ALPGGF++ E + E +RE KEET L V L
Sbjct: 202 ITTDAVVVQAGHVLMVRRQAKPGLGLIALPGGFIKQNETLVEGMLRELKEETRLKVPLPV 261
Query: 105 IVG------VYSDPNRDPRGHTVTIA-FLAVGSGEL---KAGDDAKDVTVIPIEKIEEVK 154
+ G V+ P R RG T+T A F+ + GEL K GDDA+ + + + +
Sbjct: 262 LRGSIVDSHVFDAPGRSLRGRTITHAYFIQLPGGELPAVKGGDDAQKAWWMSLADLYAQE 321
Query: 155 DKLAFDHAKIVE 166
+++ DH +I++
Sbjct: 322 EQIYEDHFQIIQ 333
>gb|AAK42441.1| MutT-like protein [Sulfolobus solfataricus]
Length = 164
Score = 72.2 bits (174), Expect = 3e-12
Identities = 42/111 (37%), Positives = 62/111 (55%), Gaps = 3/111 (2%)
Query: 45 LTVDLVIVYNNGIVFIRRKNEPYKGYLALPGGFVEYGERVEEAAVREAKEETGLDVKLLR 104
+ V +IV N ++ ++RKN P G A+PGG VEYGE +EEA RE +EETGL+V +
Sbjct: 29 VAVGCLIVEENKVLLVQRKNPPNAGLWAIPGGKVEYGETLEEALKREMREETGLEVAVGN 88
Query: 105 IVGVYSDPNRDPRGHTVTIAFLAVG-SGELKAGDDAKDVTVIPIEKIEEVK 154
I+ + N H V + F G L+A DA V +P +K+ ++
Sbjct: 89 IISIVQVINEG--FHYVILDFECKPIGGNLRASTDAVKVEYVPFDKLNIIQ 137
Database: ./suso.pep
Posted date: Jul 6, 2001 5:57 PM
Number of letters in database: 840,471
Number of sequences in database: 2977
Database: /banques/blast2/nr.pep
Posted date: Dec 14, 2000 12:46 PM
Number of letters in database: 188,266,275
Number of sequences in database: 595,510
Lambda K H
0.320 0.142 0.399
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64120863
Number of Sequences: 2977
Number of extensions: 2666263
Number of successful extensions: 6013
Number of sequences better than 1.0e-10: 14
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 5988
Number of HSP's gapped (non-prelim): 14
length of query: 173
length of database: 189,106,746
effective HSP length: 54
effective length of query: 119
effective length of database: 156,788,448
effective search space: 18657825312
effective search space used: 18657825312
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 162 (67.5 bits)